ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf67f22 |
|---|---|
| Clone Library Name | barley_pub |
>Q5U2Z7:RHG24_RAT Rho GTPase-activating protein 24 - Rattus norvegicus (Rat)| Length = 748 Score = 79.7 bits (195), Expect = 3e-14 Identities = 71/272 (26%), Positives = 118/272 (43%), Gaps = 15/272 (5%) Frame = +1 Query: 316 VFGVSTESMQCSYDSR-GNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRL 492 +FG E Y+ R GN + +L+ Q GL+ EG+FR+ + + + ++D Sbjct: 131 IFGQKLEDT-VRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAF 189 Query: 493 NSGIVPY---GIDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQCQ---SEEDCARV---- 642 + G P DVH ++ L+K + RELP V+ E + C S+E+ A V Sbjct: 190 DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYEDFLSCATLLSKEEEAGVKELT 249 Query: 643 --AKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM--TQMADPLTALMY 810 K LPV LL + + +V +NKM+A+N+A VF PN+ ++ DPLT + Sbjct: 250 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKVEDPLTIMEG 309 Query: 811 AVQVMNFLKMLIEKTLKDREESNLDDVSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSS 990 V V + ++I K + D K N ++N G + ++ ++ Sbjct: 310 TVVVQQLMSVMISK----HDRLFPKDTEPQSKPQEGPNSNNNDGHKKVTMGQLQNKENNN 365 Query: 991 FSEEPLLNSPAHSTEDKPNEANPAGGDSAPSG 1086 E P+ E + G +A SG Sbjct: 366 TKESPVRRCSWDKPESPQRSSMDNGSPTALSG 397
>Q8C4V1:RHG24_MOUSE Rho GTPase-activating protein 24 - Mus musculus (Mouse)| Length = 747 Score = 79.7 bits (195), Expect = 3e-14 Identities = 71/272 (26%), Positives = 118/272 (43%), Gaps = 15/272 (5%) Frame = +1 Query: 316 VFGVSTESMQCSYDSR-GNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRL 492 +FG E Y+ R GN + +L+ Q GL+ EG+FR+ + + + ++D Sbjct: 130 IFGQKLEDT-VRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAF 188 Query: 493 NSGIVPY---GIDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQCQ---SEEDCARV---- 642 + G P DVH ++ L+K + RELP V+ E + C S+E+ A V Sbjct: 189 DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYEDFLSCATLLSKEEEAGVKELM 248 Query: 643 --AKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM--TQMADPLTALMY 810 K LPV LL + + +V +NKM+A+N+A VF PN+ ++ DPLT + Sbjct: 249 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKVEDPLTIMEG 308 Query: 811 AVQVMNFLKMLIEKTLKDREESNLDDVSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSS 990 V V + ++I K + D K N ++N G + ++ ++ Sbjct: 309 TVVVQQLMSVMISK----HDRLFPKDTEPQSKPQDGPNSNNNDGHKKATMGQLQNKENNN 364 Query: 991 FSEEPLLNSPAHSTEDKPNEANPAGGDSAPSG 1086 E P+ E + G +A SG Sbjct: 365 TKESPVRRCSWDKPESPQRSSVDNGSPTALSG 396
>Q8N264:RHG24_HUMAN Rho GTPase-activating protein 24 - Homo sapiens (Human)| Length = 748 Score = 77.4 bits (189), Expect = 1e-13 Identities = 57/194 (29%), Positives = 94/194 (48%), Gaps = 15/194 (7%) Frame = +1 Query: 316 VFGVSTESMQCSYDSR-GNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRL 492 +FG E Y+ R GN + +L+ Q GL+ EG+FR+ + + + ++D Sbjct: 132 IFGQKLEDT-VRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAF 190 Query: 493 NSGIVPY---GIDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQC-----QSEE----DCA 636 + G P DVH ++ L+K + RELP V+ E + C + EE + A Sbjct: 191 DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELA 250 Query: 637 RVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM--TQMADPLTALMY 810 + K LPV LL + + +V +NKM+ +N+A VF PN+ ++ DPLT + Sbjct: 251 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG 310 Query: 811 AVQVMNFLKMLIEK 852 V V + ++I K Sbjct: 311 TVVVQQLMSVMISK 324
>Q10164:RGA2_SCHPO Probable Rho-type GTPase-activating protein 2 - Schizosaccharomyces| pombe (Fission yeast) Length = 1275 Score = 73.2 bits (178), Expect = 3e-12 Identities = 58/228 (25%), Positives = 108/228 (47%), Gaps = 16/228 (7%) Frame = +1 Query: 310 ASVFGVS-TESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRD 486 + +FG+ E++ S + +P ++ L + EGI+R++ S + +++ Sbjct: 1060 SGIFGLPLNEAVNISTQFNDSGLPIVVYRCIEYLESCRAEKEEGIYRLSGSASTIKHLKE 1119 Query: 487 RLNSGIVPYGI-------DVHCLSGLIKAWFRELPSGVLDP--------IPPEQVMQCQS 621 + N G V Y + DVH ++GL+K + R LP+ +LD +P Sbjct: 1120 QFNEG-VDYDLLSSDEEFDVHVIAGLLKLYLRNLPTNLLDTSMHKLFELLPNVPNDSAAL 1178 Query: 622 EEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMADPLTA 801 E C ++K LP ALLD ++ + ++ EK+NKMN RN+ +VF+P + +D Sbjct: 1179 GELCDVISK-LPPENFALLDSLLHHLRRIIAFEKVNKMNIRNVCIVFSPTLNIPSD---- 1233 Query: 802 LMYAVQVMNFLKMLIEKTLKDREESNLDDVSLSQKDPSDENGHHNPGF 945 ++ + ++N+ + + + + N D D SD+NG N F Sbjct: 1234 -IFMMLILNYDHIFTDISRQTNGAQNESD-----SDVSDDNGEDNEFF 1275
>Q9CXP4:RHG08_MOUSE Rho GTPase-activating protein 8 - Mus musculus (Mouse)| Length = 425 Score = 70.9 bits (172), Expect = 1e-11 Identities = 66/227 (29%), Positives = 103/227 (45%), Gaps = 16/227 (7%) Frame = +1 Query: 280 EVPRRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAE 459 + P P FGVS + ++ ++G +P +L L E+ GLR EG+FR +A Sbjct: 180 KTPPPRPPLPTQQFGVSLQYLRDK--NQGELIPPVLRWTVTYLREK-GLRTEGLFRRSAS 236 Query: 460 NSQEELVRDRLNSG----IVPYGIDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQCQSEE 627 V+ + G YG D+H + ++K + RELP +L EQ++ S E Sbjct: 237 AQTVRQVQRLYDQGKPVNFDDYG-DMHLPAVILKTFLRELPQPLLTFQAYEQILGITSVE 295 Query: 628 DCARVAKC------LPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMAD 789 RV C LP A+L + + + +V E NKMN+ N+A VF N+ + Sbjct: 296 SSLRVTHCRLILRSLPEHNYAVLRYLMGFLHEVSLESISNKMNSSNLACVFGLNLIWPSQ 355 Query: 790 PLTALMYAVQVMNFLKMLIE---KTLKDRE---ESNLDDVSLSQKDP 912 + +L V + F ++LIE K +E E D V + Q P Sbjct: 356 GVASLSALVPLNLFTELLIEYYDKVFSCQEAPGEHTRDTVEVQQAGP 402
>Q9NSG0:RHG08_HUMAN Rho GTPase-activating protein 8 - Homo sapiens (Human)| Length = 718 Score = 69.3 bits (168), Expect = 4e-11 Identities = 57/200 (28%), Positives = 93/200 (46%), Gaps = 10/200 (5%) Frame = +1 Query: 280 EVPRRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAE 459 + P P FGVS + ++ ++G +P +L L E+ GLR EG+FR +A Sbjct: 465 KTPPPRPPLPTQQFGVSLQYLKDK--NQGELIPPVLRFTVTYLREK-GLRTEGLFRRSAS 521 Query: 460 NSQEELVRDRLNSG----IVPYGIDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQCQSEE 627 ++ N G YG D+H + ++K + RELP +L EQ++ E Sbjct: 522 VQTVREIQRLYNQGKPVNFDDYG-DIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVE 580 Query: 628 DCARVAKC------LPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMAD 789 RV C LP +L + + + V +E NKMN+ N+A VF N+ + Sbjct: 581 SSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQ 640 Query: 790 PLTALMYAVQVMNFLKMLIE 849 +++L V + F ++LIE Sbjct: 641 GVSSLSALVPLNMFTELLIE 660
>Q8BL80:RHG22_MOUSE Rho GTPase-activating protein 22 - Mus musculus (Mouse)| Length = 702 Score = 66.6 bits (161), Expect = 2e-10 Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 21/170 (12%) Frame = +1 Query: 406 LYEQC-------GLRAEGIFRINAENSQEELVRDRLNSGIVPY---GIDVHCLSGLIKAW 555 L EQC GL EG+FR+ + + ++D + G P DVH ++ L+K + Sbjct: 181 LVEQCVDFIRERGLSEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLY 240 Query: 556 FRELPSGVLDPIPPEQVMQC---------QSEEDCARVAKCLPVAEAALLDWAVNLMADV 708 RELP V+ E + C + + A+ LP A LL + + +V Sbjct: 241 LRELPEPVIPFARYEDFLSCAQLLTKDEGEGTVELAKQVSNLPQANYNLLRYICKFLDEV 300 Query: 709 VQEEKINKMNARNIAMVFAPNM--TQMADPLTALMYAVQVMNFLKMLIEK 852 +NKM+ +N+A VF PN+ Q+ DP+T + V + + +LI K Sbjct: 301 QAHSDVNKMSVQNLATVFGPNILRPQIEDPVTIMEGTSLVQHLMTVLIRK 350
>P59281:K1688_MOUSE Protein KIAA1688 - Mus musculus (Mouse)| Length = 1107 Score = 65.9 bits (159), Expect = 4e-10 Identities = 54/192 (28%), Positives = 88/192 (45%), Gaps = 11/192 (5%) Frame = +1 Query: 307 SASVFGVSTESMQCSYDSR--GNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELV 480 S S+FG + + + R +P + + + G + EGIFR+ + + + Sbjct: 908 SPSMFGSALQEVMSMQKERYPDRQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNAL 967 Query: 481 RDRLNSGIVPYGI-DVHCLSGLIKAWFRELPSGVLDPIPPEQVMQC----QSEEDCARVA 645 + +++ VP G+ D H + L+K W+REL + IP E QC +S E V Sbjct: 968 KLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPL---IPHEFYEQCIAHYESPEAAVAVV 1024 Query: 646 KCLPVAEAALLDWAVNLMADVVQEEK--INKMNARNIAMVFAPN--MTQMADPLTALMYA 813 LP +L + + + VQ I KM+ N+AMV APN Q DP Sbjct: 1025 HALPRINRMVLCYLIRFLQVFVQPANVAITKMDVSNLAMVMAPNCLRCQSDDPRVIFENT 1084 Query: 814 VQVMNFLKMLIE 849 + M+FL++LI+ Sbjct: 1085 RKEMSFLRVLIQ 1096
>Q7Z5H3:RHG22_HUMAN Rho GTPase-activating protein 22 - Homo sapiens (Human)| Length = 698 Score = 65.5 bits (158), Expect = 6e-10 Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 21/170 (12%) Frame = +1 Query: 406 LYEQC-------GLRAEGIFRINAENSQEELVRDRLNSGIVPY---GIDVHCLSGLIKAW 555 L EQC GL EG+FR+ + + ++D + G P DVH ++ L+K + Sbjct: 175 LVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLY 234 Query: 556 FRELPSGVLDPIPPEQVMQC---------QSEEDCARVAKCLPVAEAALLDWAVNLMADV 708 RELP V+ E + C + + A+ LP A LL + + +V Sbjct: 235 LRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEV 294 Query: 709 VQEEKINKMNARNIAMVFAPNM--TQMADPLTALMYAVQVMNFLKMLIEK 852 +NKM+ +N+A VF PN+ Q+ DP+T + V + + +LI K Sbjct: 295 QAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRK 344
>Q9C0H5:K1688_HUMAN Protein KIAA1688 - Homo sapiens (Human)| Length = 1083 Score = 63.2 bits (152), Expect = 3e-09 Identities = 53/192 (27%), Positives = 87/192 (45%), Gaps = 11/192 (5%) Frame = +1 Query: 307 SASVFGVSTESMQCSYDSR--GNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELV 480 S S+FG + + + R +P + + + G + EGIFR+ + + + Sbjct: 884 SPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNAL 943 Query: 481 RDRLNSGIVPYGI-DVHCLSGLIKAWFRELPSGVLDPIPPEQVMQC----QSEEDCARVA 645 + +++ VP G+ D H + L+K W+REL + IP E QC S E V Sbjct: 944 KLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPL---IPHEFYEQCIAHYDSPEAAVAVV 1000 Query: 646 KCLPVAEAALLDWAVNLMADVVQEEKI--NKMNARNIAMVFAPN--MTQMADPLTALMYA 813 LP +L + + + VQ + KM+ N+AMV APN Q DP Sbjct: 1001 HALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVIFENT 1060 Query: 814 VQVMNFLKMLIE 849 + M+FL++LI+ Sbjct: 1061 RKEMSFLRVLIQ 1072
>Q8N103:TAGAP_HUMAN T-cell activation Rho GTPase-activating protein - Homo sapiens| (Human) Length = 731 Score = 61.2 bits (147), Expect = 1e-08 Identities = 60/234 (25%), Positives = 106/234 (45%), Gaps = 11/234 (4%) Frame = +1 Query: 421 GLRAEGIFRINAENSQEELVRDRLNSG--IVPYGIDVHCLSGLIKAWFRELPSGVLDPIP 594 G EGIFR A + +++ LNSG + + VH L+ + K + R +P +L Sbjct: 115 GPSTEGIFRRAANEKARKELKEELNSGDAVDLERLPVHLLAVVFKDFLRSIPRKLLSSDL 174 Query: 595 PEQVM---QCQSEED----CARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIA 753 E+ M + Q EED +VA LP LL V ++ + + ++N+M++ N+A Sbjct: 175 FEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLA 234 Query: 754 MVFAPNMTQMADPLTALMYAVQ--VMNFLKMLIEKTLKDREESNLDDVSLSQKDPSDENG 927 + PNM + + +L + Q + N +K L+E + + E +++ + SD++ Sbjct: 235 ICIGPNMLTLEND-QSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSL 293 Query: 928 HHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAHSTEDKPNEANPAGGDSAPSGQ 1089 H V + L N A+ + D E+N + G S+PS Q Sbjct: 294 EHTDSSDVST----------------LQNDSAYDSNDPDVESNSSSGISSPSRQ 331
>P42331:RHG25_HUMAN Rho GTPase-activating protein 25 - Homo sapiens (Human)| Length = 638 Score = 61.2 bits (147), Expect = 1e-08 Identities = 60/283 (21%), Positives = 111/283 (39%), Gaps = 19/283 (6%) Frame = +1 Query: 289 RRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQ 468 RR VFG + G + IL+ + G EGIFR+ +++ Sbjct: 140 RRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNL 199 Query: 469 EELVRDRLNSGIVP---YGIDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQC-------- 615 + +RD ++G P DVH ++ L+K + R+LP V+ E + C Sbjct: 200 VKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADE 259 Query: 616 -QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM--TQMA 786 +++++ + LP +LL + + ++ +NKM+ N+A V N+ +++ Sbjct: 260 AKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVE 319 Query: 787 DPLTALMYAVQVMNFLKMLIEKTLKDREESNLDDVSLSQKDPSDENGHHNPGFAVDSHRA 966 DP + Q+ + M+I +D E + P+ +N A S Sbjct: 320 DPAVIMRGTPQIQRVMTMMI----RDHEVLFPKSKDIPLSPPAQKNDPKKAPVARSSVGW 375 Query: 967 EGSR-----RPSSFSEEPLLNSPAHSTEDKPNEANPAGGDSAP 1080 + + R SFS + T +P++A P P Sbjct: 376 DATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVP 418
>Q7Z6I6:RHG30_HUMAN Rho GTPase-activating protein 30 - Homo sapiens (Human)| Length = 1101 Score = 60.5 bits (145), Expect = 2e-08 Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 13/180 (7%) Frame = +1 Query: 289 RRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQ 468 ++ SA VFG +Q G VP +L E+ G+ +GI+R++ +S Sbjct: 8 KKKGSAKERVFGCD---LQEHLQHSGQEVPQVLKSCAE-FVEEYGV-VDGIYRLSGVSSN 62 Query: 469 EELVRDRLNSGIVP------YGIDVHCLSGLIKAWFRELPSGVL-----DPIPPEQVMQC 615 + +R S P Y D+HC+S L KA+FRELP +L D +Q Sbjct: 63 IQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQL 122 Query: 616 QSEE--DCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMAD 789 + E V + LPV L++ + + + M+ARN+A+V+APN+ + D Sbjct: 123 EPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKD 182
>Q13459:MYO9B_HUMAN Myosin-IXb - Homo sapiens (Human)| Length = 2158 Score = 60.1 bits (144), Expect = 2e-08 Identities = 49/201 (24%), Positives = 98/201 (48%), Gaps = 13/201 (6%) Frame = +1 Query: 298 PSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEEL 477 P A FGV +S+ S SVP +L + + E GL EG++R + ++ Sbjct: 1691 PGAEPGHFGVCVDSLT----SDKASVPIVLEKLLEHV-EMHGLYTEGLYRKSGAANRTRE 1745 Query: 478 VRDRLNSGIVPYGID---VHCLSGLIKAWFRELPSGVLDPIPPEQVMQC----QSEEDCA 636 +R L + ++ +H ++G++K W RELP ++ ++ + +E A Sbjct: 1746 LRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLA 1805 Query: 637 ---RVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQM---ADPLT 798 V + LP A L+ + + V E +N+M+ +A++FAP + + +DPLT Sbjct: 1806 AIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLT 1865 Query: 799 ALMYAVQVMNFLKMLIEKTLK 861 ++ +++ ++MLI++ ++ Sbjct: 1866 SMKDVLKITTCVEMLIKEQMR 1886
>Q69ZH9:RHG23_MOUSE Rho GTPase-activating protein 23 - Mus musculus (Mouse)| Length = 1483 Score = 59.7 bits (143), Expect = 3e-08 Identities = 52/225 (23%), Positives = 100/225 (44%), Gaps = 14/225 (6%) Frame = +1 Query: 289 RRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQ 468 ++ A+ FG+ E +C + VP I+ R + E GL + GI+R+ N+ Sbjct: 889 KKNKKAAPRAFGIRLE--ECQPATENQRVPLIVAACCR-IVEARGLESTGIYRVPGNNAV 945 Query: 469 EELVRDRLNSGIVPYGI------DVHCLSGLIKAWFRELPSGVLDPIPPEQVMQCQSEED 630 ++++LN G + D++ +S L+KA+FR+LP + ++ ED Sbjct: 946 VSSLQEQLNRGPSDINLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIED 1005 Query: 631 CA-------RVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMA- 786 ++ + LP L + V + + + NKM RN+A+VF P + + + Sbjct: 1006 SRERMKTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSE 1065 Query: 787 DPLTALMYAVQVMNFLKMLIEKTLKDREESNLDDVSLSQKDPSDE 921 D +T + V M ++E ++ + DD ++ P D+ Sbjct: 1066 DNMTDM---VTHMPDRYKIVETLIQHSDWFFSDDEDKGERTPVDD 1107
>Q5SSM3:RICH2_MOUSE Rho GTPase-activating protein RICH2 - Mus musculus (Mouse)| Length = 814 Score = 58.5 bits (140), Expect = 7e-08 Identities = 49/222 (22%), Positives = 105/222 (47%), Gaps = 23/222 (10%) Frame = +1 Query: 415 QCGLRAEGIFRINAENSQEELVRDRLNSGIVP---YGIDVHCLSGLIKAWFRELPSGVLD 585 +CG++ EG+FR+ S+ + ++ L+ +V Y D H ++G +K++ RELP ++ Sbjct: 281 ECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMT 340 Query: 586 -PIPPEQVMQCQSEEDCARV------AKCLPVAEAALLDWAVNLMADVVQEEKINKMNAR 744 + E + +E R+ + LP A + + + ++ + + + +NKM Sbjct: 341 FELYDEWIQASNIQEQDKRLQALWNACEKLPKANHNNIKYLIKFLSKLSEYQDVNKMTPS 400 Query: 745 NIAMVFAPNM--TQMADPLTALMYAV--QVMNFLKMLIEKTLKDREESNLDDVSLSQKDP 912 N+A+V PN+ Q +T +M V Q++ ++ +I+ D + +L+ Sbjct: 401 NMAIVLGPNLLWPQSEGNITEMMTTVSLQIVGIIEPIIQHA--DWFFPGEIEFNLTGSYG 458 Query: 913 SDENGHHNPGFA---------VDSHRAEGSRRPSSFSEEPLL 1011 S + +HN ++ D + E +RRP S + + ++ Sbjct: 459 SPVHVNHNANYSSMPSPDMDPADRRQPEQARRPLSVATDNMM 500
>Q8BYW1:RHG25_MOUSE Rho GTPase-activating protein 25 - Mus musculus (Mouse)| Length = 648 Score = 58.5 bits (140), Expect = 7e-08 Identities = 46/200 (23%), Positives = 89/200 (44%), Gaps = 14/200 (7%) Frame = +1 Query: 289 RRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQ 468 R A + S +VFG + G + IL+ + G+ EGIFR+ +++ Sbjct: 148 RVAGTPSGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGVSEEGIFRLPGQDNL 207 Query: 469 EELVRDRLNSGIVP---YGIDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQC-------- 615 + +RD ++G P DVH ++ L+K + R+LP V+ E + C Sbjct: 208 VKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLMNADE 267 Query: 616 -QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM--TQMA 786 +++++ + LP LL + + ++ +NKM+ N+A V N+ +++ Sbjct: 268 AKAQQELVKQLSTLPRDNYNLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVE 327 Query: 787 DPLTALMYAVQVMNFLKMLI 846 DP + Q+ + M+I Sbjct: 328 DPAVIMRGTPQIQRVMTMMI 347
>O14014:RGA3_SCHPO Probable Rho-type GTPase-activating protein 3 - Schizosaccharomyces| pombe (Fission yeast) Length = 969 Score = 58.5 bits (140), Expect = 7e-08 Identities = 50/207 (24%), Positives = 96/207 (46%), Gaps = 12/207 (5%) Frame = +1 Query: 277 PEVPRRAP--SASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRI 450 PE+P R P S ++FG S E+ G+ +P ++ M + + GL EGI+RI Sbjct: 762 PEMPTRMPPPGPSPTMFGRSLENQ---LKIEGSVLPQVIAMCVSCV-DAHGLEVEGIYRI 817 Query: 451 NAENSQEELVRDRLNSGIVPYG---IDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQCQS 621 + SQ ++ D +G + D+ + ++K + LP V+ E++++ + Sbjct: 818 SGSASQVRVLVDEFENGSIRMEHLTSDLFACTSVLKTYLHRLPEPVIPGTQYEELLEAEK 877 Query: 622 ----EEDCARVA---KCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQ 780 EE RV K L A ++ + + + V + + N MN++N++ VFAP + + Sbjct: 878 IEKEEEKIERVVEVMKTLHPAHLSVFRFLIAHLGRVCKHAEKNLMNSKNVSTVFAPTLMR 937 Query: 781 MADPLTALMYAVQVMNFLKMLIEKTLK 861 L +A + L+ +++ K Sbjct: 938 DKVNRFDLQHATKKSTALQFMLDNVDK 964
>Q9P227:RHG23_HUMAN Rho GTPase-activating protein 23 - Homo sapiens (Human)| Length = 1491 Score = 58.2 bits (139), Expect = 9e-08 Identities = 51/226 (22%), Positives = 98/226 (43%), Gaps = 18/226 (7%) Frame = +1 Query: 289 RRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQ 468 ++ A+ FGV E +C + VP I+ R + E GL + GI+R+ N+ Sbjct: 893 KKNKKAAPRAFGVRLE--ECQPATENQRVPLIVAACCR-IVEARGLESTGIYRVPGNNAV 949 Query: 469 EELVRDRLNSGIVPYGI------DVHCLSGLIKAWFRELPSGVLDPIPPEQVMQCQSEED 630 ++++LN G + D++ +S L+K++FR+LP + ++ ED Sbjct: 950 VSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIED 1009 Query: 631 CA-------RVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQ--- 780 ++ + LP L + V + + + NKM RN+A+VF P + + Sbjct: 1010 ARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSE 1069 Query: 781 --MADPLTALMYAVQVMNFLKMLIEKTLKDREESNLDDVSLSQKDP 912 M D +T + +++ L + D E+ + + K+P Sbjct: 1070 DNMTDMVTHMPDRYKIVETLIQHSDWFFSDEEDKG-ERTPVGDKEP 1114
>Q68EM7:RHG17_HUMAN Rho GTPase-activating protein 17 - Homo sapiens (Human)| Length = 881 Score = 58.2 bits (139), Expect = 9e-08 Identities = 58/237 (24%), Positives = 106/237 (44%), Gaps = 19/237 (8%) Frame = +1 Query: 415 QCGLRAEGIFRINAENSQEELVRDRLN---SGIVPYGIDVHCLSGLIKAWFRELPSGVLD 585 + G++ EG+FRI A S+ + ++ L+ S + + D H ++G +K++ RELP ++ Sbjct: 278 ETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMT 337 Query: 586 PIPPEQVMQCQSEED-------CARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNAR 744 E+ Q S +D R + LP + + +A + Q +NKM Sbjct: 338 FNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPS 397 Query: 745 NIAMVFAPNMTQMADPLT----ALMYAVQVMNFLKMLIEKT---LKDREESNLDDVSLSQ 903 NIA+V PN+ + T A +V V+ ++ +I+ + E N+ + + Sbjct: 398 NIAIVLGPNLLWARNEGTLAEMAAATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPL 457 Query: 904 KDPSDENGHHNPGFAVDSHRAEGSRRPSSFS--EEPLLNSPAHSTEDKPNEANPAGG 1068 PS + H G DS E +RP+S + E L+ + + +A+ GG Sbjct: 458 TTPSSNHSFHT-GNDSDSGTLE-RKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGG 512
>Q9PT60:RBP1A_XENLA RalA-binding protein 1-A - Xenopus laevis (African clawed frog)| Length = 655 Score = 57.4 bits (137), Expect = 2e-07 Identities = 44/166 (26%), Positives = 83/166 (50%), Gaps = 9/166 (5%) Frame = +1 Query: 412 EQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYGIDV--HCLSGLIKAWFRELPSGVLD 585 EQ G++ EGI+R++ S+ + ++ + P D + ++ L+K + RELP VL Sbjct: 216 EQHGMKCEGIYRVSGIKSKVDELKAAYDREESPNLEDYEPYTVASLLKQYLRELPENVLT 275 Query: 586 P-IPPEQVMQC------QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNAR 744 + P C + ++C R+ K LP L W V M V+++E KMN + Sbjct: 276 KDLMPRFEEACGKTTEGERLQECQRLLKELPECNFCLTSWLVVHMDHVIEQELETKMNIQ 335 Query: 745 NIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDREESNL 882 NI++V +P + Q+++ + + + F + I++ +K SN+ Sbjct: 336 NISIVLSPTV-QISNRVLYVFFTHVQELFGGVQIKRVIKPLRWSNM 380
>Q63358:MYO9B_RAT Myosin-IXb - Rattus norvegicus (Rat)| Length = 1980 Score = 57.4 bits (137), Expect = 2e-07 Identities = 47/194 (24%), Positives = 95/194 (48%), Gaps = 13/194 (6%) Frame = +1 Query: 319 FGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLNS 498 FGV +S+ S SVP +L + + E GL EG++R + ++ +R L + Sbjct: 1658 FGVCVDSLT----SDKASVPIVLEKLLEHV-EMHGLYTEGLYRKSGAANRTRELRQALQT 1712 Query: 499 GIVPYGID---VHCLSGLIKAWFRELPSGVLDPIPPEQVMQC----QSEEDCA---RVAK 648 ++ +H ++G++K W RELP ++ ++ + +E A V Sbjct: 1713 DPATVKLEDFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLD 1772 Query: 649 CLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQM---ADPLTALMYAVQ 819 LP A L+ + + V E +N+M+ +A++FAP + + +DPLT++ ++ Sbjct: 1773 HLPEANHTSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLK 1832 Query: 820 VMNFLKMLIEKTLK 861 + ++MLI++ ++ Sbjct: 1833 ITTCVEMLIKEQMR 1846
>Q9QY06:MYO9B_MOUSE Myosin-IXb - Mus musculus (Mouse)| Length = 2114 Score = 57.4 bits (137), Expect = 2e-07 Identities = 47/194 (24%), Positives = 96/194 (49%), Gaps = 13/194 (6%) Frame = +1 Query: 319 FGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLNS 498 FGV +S+ S SVP +L + + E GL EG++R + ++ +R L + Sbjct: 1656 FGVCVDSLT----SDKASVPIVLEKLLEHV-EMHGLYTEGLYRKSGAANRTRELRQALQT 1710 Query: 499 GIVPYGID---VHCLSGLIKAWFRELPSGVL------DPIPPEQVMQCQSEEDCA-RVAK 648 ++ +H ++G++K W RELP ++ D + ++ + Q + V Sbjct: 1711 DPAAVKLEDFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLSAIYAVLD 1770 Query: 649 CLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQM---ADPLTALMYAVQ 819 LP A L+ + + V E +N+M+ +A++FAP + + +DPLT++ ++ Sbjct: 1771 HLPEANHTSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLK 1830 Query: 820 VMNFLKMLIEKTLK 861 + ++MLI++ ++ Sbjct: 1831 ITTCVEMLIKEQMR 1844
>Q80Y19:RHGBA_MOUSE Rho GTPase-activating protein 11A precursor - Mus musculus (Mouse)| Length = 987 Score = 57.0 bits (136), Expect = 2e-07 Identities = 44/172 (25%), Positives = 78/172 (45%), Gaps = 7/172 (4%) Frame = +1 Query: 295 APSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEE 474 A VFGV S+ S +P+ L+ L E + EG+FR + + + Sbjct: 39 ATEIKGKVFGVPFNSLPHSVVPEFGHIPSFLVDACASLKEH--IHTEGLFRKSGSVVRLK 96 Query: 475 LVRDRLNSGIVPYGIDVHC-LSGLIKAWFRELPSGVL-----DPIPPEQVMQCQSEEDCA 636 ++ +L+ G + C ++GL+K +FRELP VL + + Q + + Sbjct: 97 ALKSKLDQGEACLSSALPCDVAGLLKQFFRELPEPVLPADLHEALFKAQQLGAEERNKAT 156 Query: 637 RVAKCLPVAEAA-LLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMAD 789 + CL +L + N + V NKM++ N+A++FAPN+ Q ++ Sbjct: 157 LLLSCLMANPTVDILRYFFNFLKSVSLRASENKMDSSNLAVIFAPNLLQTSE 208
>Q640N3:RHG30_MOUSE Rho GTPase-activating protein 30 - Mus musculus (Mouse)| Length = 1101 Score = 57.0 bits (136), Expect = 2e-07 Identities = 50/181 (27%), Positives = 84/181 (46%), Gaps = 14/181 (7%) Frame = +1 Query: 289 RRAPSASASVFGVST-ESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENS 465 ++ S+ VFG E +Q S G VP +L + E G+ +GI+R++ +S Sbjct: 8 KKKGSSKERVFGCDLREHLQHS----GQEVPQVLRSCAEFVQEY-GV-VDGIYRLSGVSS 61 Query: 466 QEELVRDRLNSGIVP------YGIDVHCLSGLIKAWFRELPSGVL-----DPIPPEQVMQ 612 + +R + P Y D+HC+S L KA+FRELP +L D +Q Sbjct: 62 NIQKLRQEFETERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVAVQ 121 Query: 613 CQSEE--DCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMA 786 + E V + LP+ L++ + + + M+ARN+A+V+APN+ + Sbjct: 122 LEPERLVKILEVLQELPIQNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSK 181 Query: 787 D 789 D Sbjct: 182 D 182
>Q17R89:RICH2_HUMAN Rho GTPase-activating protein RICH2 - Homo sapiens (Human)| Length = 818 Score = 56.2 bits (134), Expect = 3e-07 Identities = 46/222 (20%), Positives = 106/222 (47%), Gaps = 23/222 (10%) Frame = +1 Query: 415 QCGLRAEGIFRINAENSQEELVRDRLNSGIVP---YGIDVHCLSGLIKAWFRELPSGVLD 585 +CG++ EG+FR+ S+ + ++ L+ +V Y D H ++G +K++ RELP ++ Sbjct: 281 ECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMT 340 Query: 586 PIPPEQVMQCQSEEDCARVAKCL-------PVAEAALLDWAVNLMADVVQEEKINKMNAR 744 ++ +Q + ++ + + L P A + + + ++ + + + +NKM Sbjct: 341 FELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPS 400 Query: 745 NIAMVFAPNM--TQMADPLTALMYAV--QVMNFLKMLIEKTLKDREESNLDDVSLSQKDP 912 N+A+V PN+ Q +T +M V Q++ ++ +I+ D + +++ Sbjct: 401 NMAIVLGPNLLWPQAEGNITEMMTTVSLQIVGIIEPIIQHA--DWFFPGEIEFNITGNYG 458 Query: 913 SDENGHHNPGFA---------VDSHRAEGSRRPSSFSEEPLL 1011 S + +HN ++ D + E +RRP S + + ++ Sbjct: 459 SPVHVNHNANYSSMPSPDMDPADRRQPEQARRPLSVATDNMM 500
>Q99N37:RHG17_RAT Rho GTPase-activating protein 17 - Rattus norvegicus (Rat)| Length = 858 Score = 55.1 bits (131), Expect = 7e-07 Identities = 55/237 (23%), Positives = 102/237 (43%), Gaps = 19/237 (8%) Frame = +1 Query: 415 QCGLRAEGIFRINAENSQEELVRDRLN---SGIVPYGIDVHCLSGLIKAWFRELPSGVLD 585 + G++ EG+FRI A S+ + ++ L+ S + + D H ++G +K++ RELP ++ Sbjct: 278 ETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMT 337 Query: 586 PIPPEQVMQCQSEEDCAR-------VAKCLPVAEAALLDWAVNLMADVVQEEKINKMNAR 744 E+ Q S +D + + LP + + +A + Q +NKM Sbjct: 338 FSLYEEWTQVASVQDQDKKLQYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPS 397 Query: 745 NIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDRE-------ESNLDDVSLSQ 903 NIA+V PN+ T A + +IE ++ + E N+ + + Sbjct: 398 NIAIVLGPNLLWAKQEGTLAEIAAATSVHVVAVIEPIIQHADWFFPGEVEFNVSEAFVPL 457 Query: 904 KDPSDENGHHNPGFAVDSHRAEGSRRPSSFS--EEPLLNSPAHSTEDKPNEANPAGG 1068 P+ + H G DS E +RP+S + E L+ + + +A+ GG Sbjct: 458 ATPNSNHSSHT-GNDSDSGTLE-RKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGG 512
>Q3UIA2:RHG17_MOUSE Rho GTPase-activating protein 17 - Mus musculus (Mouse)| Length = 846 Score = 55.1 bits (131), Expect = 7e-07 Identities = 55/237 (23%), Positives = 102/237 (43%), Gaps = 19/237 (8%) Frame = +1 Query: 415 QCGLRAEGIFRINAENSQEELVRDRLN---SGIVPYGIDVHCLSGLIKAWFRELPSGVLD 585 + G++ EG+FRI A S+ + ++ L+ S + + D H ++G +K++ RELP ++ Sbjct: 278 ETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMT 337 Query: 586 PIPPEQVMQCQSEEDCAR-------VAKCLPVAEAALLDWAVNLMADVVQEEKINKMNAR 744 E+ Q S +D + + LP + + +A + Q +NKM Sbjct: 338 FSLYEEWTQVASVQDQDKKLQYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPS 397 Query: 745 NIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDRE-------ESNLDDVSLSQ 903 NIA+V PN+ T A + +IE ++ + E N+ + + Sbjct: 398 NIAIVLGPNLLWAKQEGTLAEIAAATSVHVVAVIEPIIQHADWFFPGEVEFNVSEAFVPL 457 Query: 904 KDPSDENGHHNPGFAVDSHRAEGSRRPSSFS--EEPLLNSPAHSTEDKPNEANPAGG 1068 P+ + H G DS E +RP+S + E L+ + + +A+ GG Sbjct: 458 ATPNSNHSSHT-GNDSDSGTLE-RKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGG 512
>P15882:CHIN_HUMAN N-chimaerin - Homo sapiens (Human)| Length = 459 Score = 54.3 bits (129), Expect = 1e-06 Identities = 48/178 (26%), Positives = 86/178 (48%), Gaps = 13/178 (7%) Frame = +1 Query: 376 PTILLMMQRRLYEQCGLRAEGIFRINA-----ENSQEELVRDRLNSGI-VPYGIDVHCLS 537 P ++ M R + E GL +EG++R++ E+ + RD + I V D++ ++ Sbjct: 282 PMVVDMCIREI-ESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIIT 340 Query: 538 GLIKAWFRELPSGVL--DPIPP----EQVMQCQSE-EDCARVAKCLPVAEAALLDWAVNL 696 G +K +FR+LP ++ D P ++M + E K LP A L + + Sbjct: 341 GALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAH 400 Query: 697 MADVVQEEKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDRE 870 + V EK N MNA N+ +VF P T M P M A+ + + ++++E +K+ + Sbjct: 401 LKRVTLHEKENLMNAENLGIVFGP--TLMRSPELDAMAALNDIRYQRLVVELLIKNED 456
>Q17QN0:CHIN_BOVIN N-chimaerin - Bos taurus (Bovine)| Length = 334 Score = 54.3 bits (129), Expect = 1e-06 Identities = 49/184 (26%), Positives = 88/184 (47%), Gaps = 13/184 (7%) Frame = +1 Query: 358 SRGNSVPTILLMMQRRLYEQCGLRAEGIFRINA-----ENSQEELVRDRLNSGI-VPYGI 519 +R P ++ M R + E GL +EG++R++ E+ + RD + I V Sbjct: 151 ARTTKRPMVVDMCIREI-EARGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYE 209 Query: 520 DVHCLSGLIKAWFRELPSGVL--DPIPP----EQVMQCQSE-EDCARVAKCLPVAEAALL 678 D++ ++G +K +FR+LP ++ D P ++M + E K LP A L Sbjct: 210 DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETL 269 Query: 679 DWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTL 858 + + + V EK N MNA N+ +VF P T M P M A+ + + ++++E + Sbjct: 270 RYLMAHLKRVTLHEKENLMNAENLGIVFGP--TLMRSPELDAMAALNDIRYQRLVVELLI 327 Query: 859 KDRE 870 K+ + Sbjct: 328 KNED 331
>Q07960:RHG01_HUMAN Rho GTPase-activating protein 1 - Homo sapiens (Human)| Length = 439 Score = 53.1 bits (126), Expect = 3e-06 Identities = 52/203 (25%), Positives = 84/203 (41%), Gaps = 11/203 (5%) Frame = +1 Query: 274 EPEVPRRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQC-GLRAEGIFRI 450 +P PR P FGVS + +Q + P +++ + Y Q L EGIFR Sbjct: 229 KPMPPR--PPLPNQQFGVSLQHLQ---EKNPEQEPIPIVLRETVAYLQAHALTTEGIFRR 283 Query: 451 NAENSQEELVRDRLNSGIVPYGID----VHCLSGLIKAWFRELPSGVL--DPIPPE---- 600 +A V+ + N G+ P D +H + ++K + RELP +L D P Sbjct: 284 SANTQVVREVQQKYNMGL-PVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFL 342 Query: 601 QVMQCQSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQ 780 + + Q +V + LP +L + + + NKM N+A+VF PN+ Sbjct: 343 NIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLW 402 Query: 781 MADPLTALMYAVQVMNFLKMLIE 849 D L + F K L++ Sbjct: 403 AKDAAITLKAINPINTFTKFLLD 425
>Q9Y3L3:3BP1_HUMAN SH3 domain-binding protein 1 - Homo sapiens (Human)| Length = 701 Score = 53.1 bits (126), Expect = 3e-06 Identities = 42/160 (26%), Positives = 80/160 (50%), Gaps = 17/160 (10%) Frame = +1 Query: 421 GLRAEGIFRINAENSQEELVRDRLNS---GIVPYGIDVHCLSGLIKAWFRELPSGVLDPI 591 G++ EG+FR+ A S + ++ + S + + D H ++G +K++ RELP ++ Sbjct: 304 GMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLMTFD 363 Query: 592 PPEQVMQCQS-EEDCAR------VAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNI 750 + M+ S +E AR V LP + L + + +A + +E+++NKM NI Sbjct: 364 LYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNI 423 Query: 751 AMVFAPNMT-------QMADPLTALMYAVQVMNFLKMLIE 849 A+V PN+ A A + ++QV+ ++ LI+ Sbjct: 424 AIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQ 463
>Q62796:RBP1_RAT RalA-binding protein 1 - Rattus norvegicus (Rat)| Length = 647 Score = 52.4 bits (124), Expect = 5e-06 Identities = 52/215 (24%), Positives = 103/215 (47%), Gaps = 12/215 (5%) Frame = +1 Query: 274 EPEVPRRAPSASASVFGVS-TESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRI 450 EPEVP+ + +FG ++++ + G +P + + E+ G++ EGI+R+ Sbjct: 175 EPEVPQTDAPSLRPIFGAPFADAVERTMMYDGIRLPAVFRECVDYM-EKHGMKCEGIYRV 233 Query: 451 NAENSQEELVR---DRLNS-GIVPYGIDVHCLSGLIKAWFRELPSGVLDP-IPPEQVMQC 615 + S+ + ++ DR S + Y + + ++ L+K + R+LP +L + P C Sbjct: 234 SGIKSKVDELKAAYDREESPNLEEY--EPNTVASLLKQYLRDLPENLLTKELMPRFEEAC 291 Query: 616 ------QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMT 777 + ++ R+ + LP LL W + M V+ +E KMN +NI++V +P + Sbjct: 292 GRTTEVEKVQEFQRLLRELPEYNHLLLSWLIVHMDHVIAKELETKMNIQNISIVLSPTVQ 351 Query: 778 QMADPLTALMYAVQVMNFLKMLIEKTLKDREESNL 882 L L VQ + F +L+++ + SN+ Sbjct: 352 ISNRVLYVLFTHVQEL-FGTVLLKQVTRPLRWSNM 385
>Q62172:RBP1_MOUSE RalA-binding protein 1 - Mus musculus (Mouse)| Length = 648 Score = 52.0 bits (123), Expect = 6e-06 Identities = 50/215 (23%), Positives = 104/215 (48%), Gaps = 12/215 (5%) Frame = +1 Query: 274 EPEVPRRAPSASASVFGVS-TESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRI 450 EPEVP+ + +FGV ++++ + G +P + + E+ G++ EG++R+ Sbjct: 175 EPEVPQMDAPSVKPIFGVPLVDAVERTMMYDGVRLPAVFRECVDYM-EKHGMKCEGVYRV 233 Query: 451 NAENSQEELVR---DRLNS-GIVPYGIDVHCLSGLIKAWFRELPSGVLDP-IPPEQVMQC 615 + S+ + ++ DR S + Y + + ++ L+K + R+LP +L + P C Sbjct: 234 SGIKSKVDELKAAYDREESPNLEEY--EPNTVASLLKQYLRDLPENLLTKELMPRFEEAC 291 Query: 616 ------QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMT 777 + ++ R+ + LP LL W + + V+ +E KMN +NI++V +P + Sbjct: 292 GKTTEMEKVQEFQRLLRELPECNHLLLSWLIVHLDHVIAKELETKMNIQNISIVLSPTVQ 351 Query: 778 QMADPLTALMYAVQVMNFLKMLIEKTLKDREESNL 882 L L VQ + F +++++ + SN+ Sbjct: 352 ISNRVLYVLFTHVQEL-FGTVVLKQVTRPLRWSNM 385
>Q15311:RBP1_HUMAN RalA-binding protein 1 - Homo sapiens (Human)| Length = 655 Score = 52.0 bits (123), Expect = 6e-06 Identities = 48/214 (22%), Positives = 105/214 (49%), Gaps = 11/214 (5%) Frame = +1 Query: 274 EPEVPRRAPSASASVFGVS-TESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRI 450 EPEVP+ +FG+ ++++ + G +P + + E+ G++ EGI+R+ Sbjct: 175 EPEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYV-EKYGMKCEGIYRV 233 Query: 451 NAENSQEELVR---DRLNSGIVPYGIDVHCLSGLIKAWFRELPSGVLDP-IPPEQVMQC- 615 + S+ + ++ DR S + + + ++ L+K + R+LP +L + P C Sbjct: 234 SGIKSKVDELKAAYDREESTNLE-DYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACG 292 Query: 616 -----QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQ 780 + ++ R+ K LP L+ W + M V+ +E KMN +NI++V +P + Q Sbjct: 293 RTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV-Q 351 Query: 781 MADPLTALMYAVQVMNFLKMLIEKTLKDREESNL 882 +++ + + + F +++++ +K SN+ Sbjct: 352 ISNRVLYVFFTHVQELFGNVVLKQVMKPLRWSNM 385
>Q80XD1:CHIO_MOUSE Beta-chimaerin - Mus musculus (Mouse)| Length = 332 Score = 52.0 bits (123), Expect = 6e-06 Identities = 42/172 (24%), Positives = 82/172 (47%), Gaps = 16/172 (9%) Frame = +1 Query: 403 RLYEQCGLRAEGIFRINAENSQEELVR---DR------LNSGIVPYGIDVHCLSGLIKAW 555 R E GL++EG++R++ E V+ DR +++ I P D++ ++G +K + Sbjct: 163 REIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANIYP---DINIITGALKLY 219 Query: 556 FRELPSGVLDPIPPEQVMQC-------QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQ 714 FR+LP ++ + ++ + E V LP A L + + + V Sbjct: 220 FRDLPIPIITYDTYSKFIEAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTM 279 Query: 715 EEKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDRE 870 EK N MNA N+ +VF P T M P + + + M + K++++ +++ + Sbjct: 280 NEKDNLMNAENLGIVFGP--TLMRPPEDSTLTTLHDMRYQKLIVQILIENED 329
>Q6P4F7:RHGBA_HUMAN Rho GTPase-activating protein 11A precursor - Homo sapiens (Human)| Length = 1023 Score = 51.6 bits (122), Expect = 8e-06 Identities = 40/172 (23%), Positives = 80/172 (46%), Gaps = 7/172 (4%) Frame = +1 Query: 295 APSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEE 474 A +FGV ++ S +P+ L+ L + + EG+FR + + + Sbjct: 39 ATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTSLEDH--IHTEGLFRKSGSVIRLK 96 Query: 475 LVRDRLNSGIVPYGIDVHC-LSGLIKAWFRELPSGVLDPIPPEQVMQCQS-----EEDCA 636 ++++++ G C ++GL+K +FRELP +L E +++ Q + Sbjct: 97 ALKNKVDHGEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAT 156 Query: 637 RVAKCLPVAEAA-LLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMAD 789 + CL +L + N + +V NKM++ N+A++FAPN+ Q ++ Sbjct: 157 LLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSE 208
>Q03070:CHIO_RAT Beta-chimaerin - Rattus norvegicus (Rat)| Length = 295 Score = 51.6 bits (122), Expect = 8e-06 Identities = 42/172 (24%), Positives = 82/172 (47%), Gaps = 16/172 (9%) Frame = +1 Query: 403 RLYEQCGLRAEGIFRINAENSQEELVR---DR------LNSGIVPYGIDVHCLSGLIKAW 555 R E GL++EG++R++ E V+ DR +++ I P D++ ++G +K + Sbjct: 126 REIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANIYP---DINIITGALKLY 182 Query: 556 FRELPSGVLDPIPPEQVMQC-------QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQ 714 FR+LP ++ + ++ + E V LP A L + + + V Sbjct: 183 FRDLPIPIITYDTYTKFIEAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTM 242 Query: 715 EEKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDRE 870 EK N MNA N+ +VF P T M P + + + M + K++++ +++ + Sbjct: 243 NEKDNLMNAENLGIVFGP--TLMRPPEDSTLTTLHDMRYQKLIVQILIENED 292
>P52757:CHIO_HUMAN Beta-chimaerin - Homo sapiens (Human)| Length = 468 Score = 51.2 bits (121), Expect = 1e-05 Identities = 43/172 (25%), Positives = 81/172 (47%), Gaps = 16/172 (9%) Frame = +1 Query: 403 RLYEQCGLRAEGIFRINAENSQEELVR---DR------LNSGIVPYGIDVHCLSGLIKAW 555 R E GL++EG++R++ E V+ DR +++ + P D++ ++G +K + Sbjct: 299 REIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYP---DINIITGALKLY 355 Query: 556 FRELPSGVLDP------IPPEQVMQCQSE-EDCARVAKCLPVAEAALLDWAVNLMADVVQ 714 FR+LP V+ I ++ E V LP A L + + + V Sbjct: 356 FRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTM 415 Query: 715 EEKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDRE 870 EK N MNA N+ +VF P T M P + + + M + K++++ +++ + Sbjct: 416 NEKDNFMNAENLGIVFGP--TLMRPPEDSTLTTLHDMRYQKLIVQILIENED 465
>P34288:GAP_CAEEL GTPase-activating protein GAP - Caenorhabditis elegans| Length = 1317 Score = 50.4 bits (119), Expect = 2e-05 Identities = 55/251 (21%), Positives = 105/251 (41%), Gaps = 21/251 (8%) Frame = +1 Query: 412 EQCGLRAEGIFRINAENSQEELVRDRLNS------------GIVPYGIDVHCLSGLIKAW 555 E G+ GI+RI + +++ L++ + P DV+ +S L+K + Sbjct: 686 ETYGMDTVGIYRIPGNTAAVNALKESLSNRGFDSVDLSKVESLDPRWRDVNVVSSLLKMF 745 Query: 556 FRELPSGVL-DPIPPEQVMQCQSEEDCARVAKC------LPVAEAALLDWAVNLMADVVQ 714 R+LP +L D + P + + R+ K LP L + + ++++ + Sbjct: 746 LRKLPEPLLTDKLYPFFIDANRISTHHNRLHKLRNLLRKLPRPHYDTLRFLIVHLSEITK 805 Query: 715 EEKINKMNARNIAMVFAPNMTQMADPLTALM--YAVQVMNFLKMLIEKTLKDREESNLDD 888 +NKM RN+A++F P++ + +D A M + ++ LI L +ES+ + Sbjct: 806 HSDVNKMECRNLALMFGPSIVRPSDDNMATMVTHMSDQCKIIETLIHYNLWMFDESSTTE 865 Query: 889 VSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAHSTEDKPNEANPAGG 1068 ++ ++ P+D PG G P+ S + H+ K NE A Sbjct: 866 DAVPEQHPADGQNPLEPG-------GYGVGVPTGVSAASF--NDMHNLIRKANEDQAAAM 916 Query: 1069 DSAPSGQTVMN 1101 + GQ + N Sbjct: 917 MNEGKGQKIKN 927
>Q91V57:CHIN_MOUSE N-chimaerin - Mus musculus (Mouse)| Length = 459 Score = 50.4 bits (119), Expect = 2e-05 Identities = 46/178 (25%), Positives = 86/178 (48%), Gaps = 13/178 (7%) Frame = +1 Query: 376 PTILLMMQRRLYEQCGLRAEGIFRINA-----ENSQEELVRDRLNSGI-VPYGIDVHCLS 537 P ++ M R + E GL +EG++R++ E+ + RD + I V D++ ++ Sbjct: 282 PMVVDMCIREI-ESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIIT 340 Query: 538 GLIKAWFRELPSGVL--DPIP----PEQVMQCQSE-EDCARVAKCLPVAEAALLDWAVNL 696 G +K +FR+LP ++ D P ++M + E + LP A L + + Sbjct: 341 GALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALRSLPPAHCETLRYLMAH 400 Query: 697 MADVVQEEKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDRE 870 + V EK N M+A N+ +VF P T M P M A+ + + ++++E +K+ + Sbjct: 401 LKRVTLHEKENLMSAENLGIVFGP--TLMRSPELDPMAALNDIRYQRLVVELLIKNED 456
>O94466:RGA7_SCHPO Probable Rho-GTPase-activating protein 7 - Schizosaccharomyces| pombe (Fission yeast) Length = 695 Score = 50.1 bits (118), Expect = 2e-05 Identities = 33/154 (21%), Positives = 74/154 (48%), Gaps = 14/154 (9%) Frame = +1 Query: 367 NSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLNSGIV-------PYGIDV 525 +++P I++ ++ E GL +GI+R+ + +++ ++R + + + Y DV Sbjct: 517 SNIPNIVMQCTSQV-ENFGLNLQGIYRVPSSSARVNMLRSQFENNPLLQLHTPEDYENDV 575 Query: 526 HCLSGLIKAWFRELPSGVLDPIPPEQVMQCQSEEDCAR-------VAKCLPVAEAALLDW 684 H ++ L+K +FREL ++ + + ED +R LP A + + Sbjct: 576 HAVADLLKIFFRELREPLIPDNHQRDFIDAGNVEDESRRRDAVHRAINDLPDANYSTIRH 635 Query: 685 AVNLMADVVQEEKINKMNARNIAMVFAPNMTQMA 786 +A + + +NKM+ N+A+++ P + + A Sbjct: 636 LTIHLAKIKENSDVNKMSTNNLAIIWGPTIIKQA 669
>Q80YF9:TCGAP_MOUSE TC10/CDC42 GTPase-activating protein - Mus musculus (Mouse)| Length = 1305 Score = 49.7 bits (117), Expect = 3e-05 Identities = 42/150 (28%), Positives = 74/150 (49%), Gaps = 13/150 (8%) Frame = +1 Query: 364 GNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLNSGIVP------YGIDV 525 G VP +L + E G+ +GI+R++ +S + +R +S +P + D+ Sbjct: 349 GQDVPQVLRCCSEFI-EAHGV-VDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDI 406 Query: 526 HCLSGLIKAWFRELPSGVLDPIPPEQVMQCQS----EEDCARV---AKCLPVAEAALLDW 684 H +S L K +FRELP+ +L + + S EE RV + LP L++ Sbjct: 407 HSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEY 466 Query: 685 AVNLMADVVQEEKINKMNARNIAMVFAPNM 774 + +A + + M+ARN+A+V+APN+ Sbjct: 467 LLRHLARMARHSANTSMHARNLAIVWAPNL 496
>O14559:TCGAP_HUMAN TC10/CDC42 GTPase-activating protein - Homo sapiens (Human)| Length = 1287 Score = 49.7 bits (117), Expect = 3e-05 Identities = 42/150 (28%), Positives = 74/150 (49%), Gaps = 13/150 (8%) Frame = +1 Query: 364 GNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLNSGIVP------YGIDV 525 G VP +L + E G+ +GI+R++ +S + +R +S +P + D+ Sbjct: 325 GQDVPQVLRCCSEFI-EAHGV-VDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDI 382 Query: 526 HCLSGLIKAWFRELPSGVLDPIPPEQVMQCQS----EEDCARV---AKCLPVAEAALLDW 684 H +S L K +FRELP+ +L + + S EE RV + LP L++ Sbjct: 383 HSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEY 442 Query: 685 AVNLMADVVQEEKINKMNARNIAMVFAPNM 774 + +A + + M+ARN+A+V+APN+ Sbjct: 443 LLRHLARMARHSANTSMHARNLAIVWAPNL 472
>P30337:CHIN_RAT N-chimaerin - Rattus norvegicus (Rat)| Length = 334 Score = 49.7 bits (117), Expect = 3e-05 Identities = 46/178 (25%), Positives = 85/178 (47%), Gaps = 13/178 (7%) Frame = +1 Query: 376 PTILLMMQRRLYEQCGLRAEGIFRINA-----ENSQEELVRDRLNSGI-VPYGIDVHCLS 537 P ++ M R + E GL +EG++R++ E+ + RD + I V D++ ++ Sbjct: 157 PMVVDMCIREI-ESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIIT 215 Query: 538 GLIKAWFRELPSGVL--DPIP-----PEQVMQCQSEEDCARVAKCLPVAEAALLDWAVNL 696 G +K +FR+LP ++ D P + V + E + LP A L + + Sbjct: 216 GALKLYFRDLPIPLITYDAYPKFIESAKIVDPDEQLETLHEALRSLPPAHCETLRYLMAH 275 Query: 697 MADVVQEEKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDRE 870 + V EK N M+A N+ +VF P T M P M A+ + + ++++E +K+ + Sbjct: 276 LKRVTLHEKENLMSAENLGIVFGP--TLMRSPELDPMAALNDIRYQRLVVELLIKNED 331
>P32873:BEM3_YEAST GTPase-activating protein BEM3 - Saccharomyces cerevisiae (Baker's| yeast) Length = 1128 Score = 48.9 bits (115), Expect = 5e-05 Identities = 45/193 (23%), Positives = 86/193 (44%), Gaps = 34/193 (17%) Frame = +1 Query: 298 PSASASVFGVSTES-MQCSYDSRGN--SVPTILLMMQRRLYEQCGLRAEGIFRINAENSQ 468 P S ++FG S E+ ++ S N +P+++ LY+ G++ EGIFR++ ++ Sbjct: 898 PHVSTAIFGSSLETCLRLSSHKYQNVYDLPSVVYRCLEYLYKNRGIQEEGIFRLSGSSTV 957 Query: 469 EELVRDRLNS----GIVPYG---------------IDVHCLSGLIKAWFRELP------- 570 + +++R + + Y I V+ +SGL+K + R+LP Sbjct: 958 IKTLQERFDKEYDVDLCRYNESIEAKDDEASPSLYIGVNTVSGLLKLYLRKLPHLLFGDE 1017 Query: 571 -----SGVLDPIPPEQVMQCQSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKM 735 V+D V ++ + +P A +L+ L+ + + K NKM Sbjct: 1018 QFLSFKRVVDENHNNPVQISLGFKELIE-SGLVPHANLSLMYALFELLVRINENSKFNKM 1076 Query: 736 NARNIAMVFAPNM 774 N RN+ +VF+P + Sbjct: 1077 NLRNLCIVFSPTL 1089
>Q74ZH7:BEM3_ASHGO GTPase-activating protein BEM3 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 1013 Score = 48.5 bits (114), Expect = 7e-05 Identities = 42/192 (21%), Positives = 87/192 (45%), Gaps = 38/192 (19%) Frame = +1 Query: 313 SVFGVSTES--MQCSYDSRGN-SVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVR 483 +VFG S S+ +G +P+++ LY+ G++ EGIFR++ +S + ++ Sbjct: 789 AVFGADLRSCLQLSSHPYQGKYEIPSVVFRTLEFLYKNRGIQEEGIFRLSGSSSLIKSLQ 848 Query: 484 DRLNS-------------GIVPYG-------IDVHCLSGLIKAWFRELPSGVLDP---IP 594 ++ + + P +DV+ +SGL+K + R+LP + + Sbjct: 849 EQFDKEYDVDLCNYNDKVSVTPGNENQGGLYVDVNTVSGLLKLYLRKLPHMIFGDAAYMD 908 Query: 595 PEQVMQCQSEE------------DCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMN 738 +++++ ++ + R+AK AL+ L+ + + K NKMN Sbjct: 909 FKRIVERNGDDSKLIALEFRALVNSGRIAK----EYVALMYALFELLVKITENSKYNKMN 964 Query: 739 ARNIAMVFAPNM 774 RN+ +VF+P + Sbjct: 965 LRNLCIVFSPTL 976
>P46941:TG325_CAEEL WW domain-containing protein tag-325 - Caenorhabditis elegans| Length = 837 Score = 48.1 bits (113), Expect = 9e-05 Identities = 47/172 (27%), Positives = 72/172 (41%), Gaps = 14/172 (8%) Frame = +1 Query: 316 VFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVR---D 486 VFG ST S C ++ NS+ + + + E GL +GI+R++ S + +R D Sbjct: 607 VFG-STLSAICQHE---NSLVPKFIRVITEVIESKGLETDGIYRVSGNLSAVQKIRCQAD 662 Query: 487 RLNSGIVPYGIDVHCLSGLIKAWFRELPSGVLDPIPP-----EQVMQCQSEEDCARVAKC 651 + N + D+H L+G +K +FREL DP+ P E Q R K Sbjct: 663 QDNYKALVSEEDIHVLTGALKLFFREL----TDPLFPISLHKEYTSAMQMPNATTRFKKF 718 Query: 652 ------LPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMAD 789 LP L + + V N+M N+A+VF P + D Sbjct: 719 EELLSRLPNENRETLKMLLRHLNRVASHSSQNRMQQHNLAIVFGPTLFHNGD 770
>O74360:RGA4_SCHPO Probable Rho-type GTPase-activating protein 4 - Schizosaccharomyces| pombe (Fission yeast) Length = 933 Score = 48.1 bits (113), Expect = 9e-05 Identities = 37/148 (25%), Positives = 70/148 (47%), Gaps = 9/148 (6%) Frame = +1 Query: 373 VPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLNSG--IVPYGIDVHCLSGLI 546 VPT+++ + E G+ EG++R + SQ + + L + ++ D+ ++ + Sbjct: 760 VPTLIVSCINFI-ESYGMDFEGLYRKSGATSQMKKIVALLRNEDTVLDPSEDISAVTSVF 818 Query: 547 KAWFRELPSGVL---DPIPPEQVMQCQSEED----CARVAKCLPVAEAALLDWAVNLMAD 705 K + R LP+ ++ P C S +D V K LP A A +L + +A Sbjct: 819 KQYLRNLPNPIITYDQYFPFITAANCASFQDKLDGFIMVIKSLPPAHAEILQLIIRHLAR 878 Query: 706 VVQEEKINKMNARNIAMVFAPNMTQMAD 789 V N+M ++N+A+VF+P + + D Sbjct: 879 VAAYSHANRMTSKNLAVVFSPTLIRDPD 906
>Q8K2L9:TAGAP_MOUSE T-cell activation Rho GTPase-activating protein - Mus musculus| (Mouse) Length = 714 Score = 47.8 bits (112), Expect = 1e-04 Identities = 55/233 (23%), Positives = 100/233 (42%), Gaps = 10/233 (4%) Frame = +1 Query: 421 GLRAEGIFRINAENSQEELVRDRLNSGIVPY--GIDVHCLSGLIKAWFRELPSGVLDPIP 594 G EGIFR A + +++ LN G+ + VH L+ + K + R +P +L Sbjct: 115 GPSTEGIFRKAASEKARKELKEGLNCGVSVNLKQLPVHLLAVVFKDFLRGIPLKLLSCDL 174 Query: 595 PEQVM---QCQSEED----CARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIA 753 E M + +EED +VA LP LL + ++ + + ++NKM++ N+A Sbjct: 175 FEDWMGALEKPTEEDRIEALKQVAGGLPRPNLLLLRHLLYVLHLISKNAEVNKMDSSNLA 234 Query: 754 MVFAPNM-TQMADPLTALMYAVQVMNFLKMLIEKTLKDREESNLDDVSLSQKDPSDENGH 930 + PNM T D + + N +K+L+E + + E +++ + SD++ Sbjct: 235 ICIGPNMLTLKNDQSLSFQAQKDLNNKVKILVEFLIDNCFEIFGENIRTRSRITSDDSLE 294 Query: 931 HNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAHSTEDKPNEANPAGGDSAPSGQ 1089 H V + L N A+ + D + P G ++P+ Q Sbjct: 295 HTDSSDVST----------------LQNDSAYDSNDP--DVEPTSGAASPNRQ 329
>Q12979:ABR_HUMAN Active breakpoint cluster region-related protein - Homo sapiens| (Human) Length = 859 Score = 47.8 bits (112), Expect = 1e-04 Identities = 50/197 (25%), Positives = 93/197 (47%), Gaps = 19/197 (9%) Frame = +1 Query: 256 GLPVEFEPEVP------RRAPSASAS-VFGVSTESMQCSYDSRGNSVPTILLMMQRRLYE 414 G+ VEF + +R PS + VFGV + S+ VP I+ + E Sbjct: 617 GIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSK---VPYIVRQCVEEV-E 672 Query: 415 QCGLRAEGIFRINAENSQEELVR---DRLNSGIVPY--GIDVHCLSGLIKAWFRELPSGV 579 + G+ GI+RI+ + + ++ D N I+ +D++ ++G +K +FRELP + Sbjct: 673 KRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPL 732 Query: 580 L-DPIPPE-----QVMQCQSEEDCA-RVAKCLPVAEAALLDWAVNLMADVVQEEKINKMN 738 L D + P + ++E+C + + LP + + + V ++E INKM+ Sbjct: 733 LTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMS 792 Query: 739 ARNIAMVFAPNMTQMAD 789 N+A VF P + + ++ Sbjct: 793 LHNLATVFGPTLLRPSE 809
>Q8BN58:RHG28_MOUSE Rho GTPase-activating protein 28 - Mus musculus (Mouse)| Length = 729 Score = 47.4 bits (111), Expect = 2e-04 Identities = 51/206 (24%), Positives = 96/206 (46%), Gaps = 16/206 (7%) Frame = +1 Query: 205 EVQHVAHVTFDRFHGFLGLPVEFEPEVPRRAPSASASVFGVSTESMQCSYDSRGNSVPTI 384 +++H++ + F G ++ + R +FGV ++ D + + + Sbjct: 346 KIRHLSLIELTAFFDAFG--IQLKRNKTERVRGRDNGIFGVPL-TVLLDNDRKKDPAVKV 402 Query: 385 LLMMQR--RLYEQCGLRAEGIFRINAENSQEELVRDRLNS--GIVPYGIDVHC---LSGL 543 L++Q+ + E+ GL +EGIFR++ ++ + R+ L++ + D C + + Sbjct: 403 PLVLQKFFQKVEESGLESEGIFRLSGCTAKVKQYREELDARFNADKFKWDKMCHREAAVM 462 Query: 544 IKAWFRELPSGVLDPIP--PEQVMQCQSEEDCARVAKCLPVAEAAL----LDWAVNLMA- 702 +KA+FRELP+ + P+ P + + D + L + AL D A LMA Sbjct: 463 LKAFFRELPTSLF-PVEYIPAFISLMERGPDIKVQFQALHLMVMALPDANRDTAQALMAF 521 Query: 703 --DVVQEEKINKMNARNIAMVFAPNM 774 V+ E N+MN NI+ V APN+ Sbjct: 522 FNKVIANESKNRMNLWNISTVMAPNL 547
>P55194:3BP1_MOUSE SH3 domain-binding protein 1 - Mus musculus (Mouse)| Length = 601 Score = 47.4 bits (111), Expect = 2e-04 Identities = 44/175 (25%), Positives = 84/175 (48%), Gaps = 19/175 (10%) Frame = +1 Query: 382 ILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYGIDVHC-----LSGLI 546 +LL++ + E+ EG+FR+ A S + ++ + S P+ ++ C ++G + Sbjct: 217 VLLLLSEGMQEE-----EGLFRLAAGASVLKRLKQTMASD--PHSLEEFCSGPHAVAGAL 269 Query: 547 KAWFRELPSGVLDPIPPEQVMQCQS-EEDCAR------VAKCLPVAEAALLDWAVNLMAD 705 K++ RELP ++ + M+ S +E AR V LP L + + +A Sbjct: 270 KSYLRELPEPLMTSDLYDDWMRAASLKEPGARLEALHDVCSRLPQENFNNLRYLMKFLAL 329 Query: 706 VVQEEKINKMNARNIAMVFAPNMT-------QMADPLTALMYAVQVMNFLKMLIE 849 + +E+ +NKM NIA+V PN+ A A + ++QV+ ++ LI+ Sbjct: 330 LAEEQDVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQ 384
>Q8BRH3:RHG19_MOUSE Rho GTPase-activating protein 19 - Mus musculus (Mouse)| Length = 494 Score = 46.6 bits (109), Expect = 3e-04 Identities = 39/150 (26%), Positives = 68/150 (45%), Gaps = 28/150 (18%) Frame = +1 Query: 409 YEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYGIDVHCLSG---------LIKAWFR 561 Y LR EG+FR+ + +++L+RD LN+ G D+ SG L+K + Sbjct: 131 YLHKNLRVEGLFRVPGNSVRQQLLRDALNN-----GTDIDLDSGEFHSNDVATLLKMFLG 185 Query: 562 ELPSGVLD------PIPPEQVMQCQSEEDCARVAK-------------CLPVAEAALLDW 684 ELP +L + +MQ + + + LP A LL Sbjct: 186 ELPEPLLTHKHFHVHLKIADLMQFDDKGNKTNIPDKERQIEALQLLFLILPPANRNLLKL 245 Query: 685 AVNLMADVVQEEKINKMNARNIAMVFAPNM 774 ++L+ +++ NKM+A N+A++FAP++ Sbjct: 246 LLDLLYQTAKKQDKNKMSAHNLALMFAPHV 275
>Q5F3G0:RHG19_CHICK Rho GTPase-activating protein 19 - Gallus gallus (Chicken)| Length = 495 Score = 46.2 bits (108), Expect = 3e-04 Identities = 40/150 (26%), Positives = 69/150 (46%), Gaps = 28/150 (18%) Frame = +1 Query: 409 YEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYGIDVHCLSG---------LIKAWFR 561 Y LRAEG+FR+ + ++++++D LNS G D+ SG L+K + Sbjct: 127 YLHKNLRAEGLFRVPGNSIRQQILKDALNS-----GTDIDLDSGEFHSNDVATLLKMFLG 181 Query: 562 ELPSGVL------------DPIPPEQVMQCQSEEDCARVAKC-------LPVAEAALLDW 684 ELP +L D ++ S D R + LP +LL Sbjct: 182 ELPEPLLTHKHFHAHLKIADLTLFDEKGNKTSTPDKERQIEALQLLFLILPAPNRSLLKL 241 Query: 685 AVNLMADVVQEEKINKMNARNIAMVFAPNM 774 ++L+ +++ NKM+A N+A++FAP++ Sbjct: 242 LLDLLYQTAKKQDKNKMSAHNLALMFAPHI 271
>Q6PAJ1:BCR_MOUSE Breakpoint cluster region protein - Mus musculus (Mouse)| Length = 1270 Score = 45.4 bits (106), Expect = 6e-04 Identities = 42/180 (23%), Positives = 85/180 (47%), Gaps = 13/180 (7%) Frame = +1 Query: 289 RRAPSASAS-VFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENS 465 +R PS + VFGV + S+ VP I+ + E+ G+ GI+R++ + Sbjct: 1040 KRMPSRKQTGVFGVKIAVVTKRERSK---VPYIVRQCVEEI-ERRGMEEVGIYRVSGVAT 1095 Query: 466 QEELVR-----DRLNSGIVPYGIDVHCLSGLIKAWFRELPSGVL-DPIPPE-----QVMQ 612 + ++ + + ++ +DV+ ++G +K +FRELP + D P + Sbjct: 1096 DIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSD 1155 Query: 613 CQSEEDCA-RVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMAD 789 ++E C + LP A + ++ + V ++E +NKM+ N+A VF P + + ++ Sbjct: 1156 PVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKETVNKMSLHNLATVFGPTLLRSSE 1215
>Q9P2F6:RHG20_HUMAN Rho GTPase-activating protein 20 - Homo sapiens (Human)| Length = 1191 Score = 45.1 bits (105), Expect = 8e-04 Identities = 44/195 (22%), Positives = 91/195 (46%), Gaps = 13/195 (6%) Frame = +1 Query: 316 VFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLN 495 +FG+S ++ C D+ V +L + ++ G +GIFR +A ++++LN Sbjct: 362 LFGISLPNI-CENDNLPKPVLDMLFFLNQK-----GPLTKGIFRQSANVKSCRELKEKLN 415 Query: 496 SGIVPYGID---VHCLSGLIKAWFRELPSGVLDPIPPEQ---VMQCQSEED----CARVA 645 SG+ + +D + ++ ++K + R +P + + VM ++E+ R+ Sbjct: 416 SGVEVH-LDCESIFVIASVLKDFLRNIPGSIFSSDLYDHWVSVMDQGNDEEKINTVQRLL 474 Query: 646 KCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM---TQMADPLTALMYAV 816 LP A LL + ++ ++ Q N+M A N+A+ AP++ + P + Sbjct: 475 DQLPRANVVLLRYLFGVLHNIEQHSSSNQMTAFNLAVCVAPSILWPPASSSPELENEFTK 534 Query: 817 QVMNFLKMLIEKTLK 861 +V ++ LIE L+ Sbjct: 535 KVSLLIQFLIENCLR 549
>P11274:BCR_HUMAN Breakpoint cluster region protein - Homo sapiens (Human)| Length = 1271 Score = 45.1 bits (105), Expect = 8e-04 Identities = 42/180 (23%), Positives = 85/180 (47%), Gaps = 13/180 (7%) Frame = +1 Query: 289 RRAPSASAS-VFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENS 465 +R PS + VFGV + S+ VP I+ + E+ G+ GI+R++ + Sbjct: 1041 KRMPSRKQTGVFGVKIAVVTKRERSK---VPYIVRQCVEEI-ERRGMEEVGIYRVSGVAT 1096 Query: 466 QEELVR-----DRLNSGIVPYGIDVHCLSGLIKAWFRELPSGVL-DPIPPE-----QVMQ 612 + ++ + + ++ +DV+ ++G +K +FRELP + D P + Sbjct: 1097 DIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSD 1156 Query: 613 CQSEEDCA-RVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMAD 789 ++E C + LP A + ++ + V ++E +NKM+ N+A VF P + + ++ Sbjct: 1157 PVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSE 1216
>Q9VDG2:RLIP_DROME RalA-binding protein 1 - Drosophila melanogaster (Fruit fly)| Length = 625 Score = 44.7 bits (104), Expect = 0.001 Identities = 69/316 (21%), Positives = 127/316 (40%), Gaps = 36/316 (11%) Frame = +1 Query: 316 VFGVS----TESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQ----E 471 VFGVS TE +C + V L++ + Q L+ E I++I ++ + Sbjct: 186 VFGVSVSLATERSRCH-----DGVDIPLVVRDCIDFLQDHLKCEQIYKIEPIKTRLMHFK 240 Query: 472 ELVRDRLNSGIVPYGIDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQCQS-------EED 630 L +R + V +++ L+K + RELP +L + + S + + Sbjct: 241 RLYNNREHDSAVDE-LNLPTACSLLKLFLRELPEPLLTTDLVARFEEVASHPKVTTQQAE 299 Query: 631 CARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQMADPLTALM- 807 ++ + LP LL W + V+Q+E+ NK+NA+++AM+ +P + + AL+ Sbjct: 300 LQQLLEQLPKCNRTLLAWVLLHFDAVIQQERHNKLNAQSLAMLLSPTLQMSHRLMVALLC 359 Query: 808 ------YAVQVMNFLKMLIEKT--LKDREESNLDDVSLSQKDPSDENGHHNPGFAVDSHR 963 VQ++ ++ L + L D E ++ S + N GF Sbjct: 360 HCNNLFADVQLIKYVPPLTSTSPKLPDTPEDIQTELRKQDSLLSQIHSEMNAGFITKKRE 419 Query: 964 ----------AEGSRRPSSF--SEEPLLNSPAHSTEDKPNEANPAGGDSAPSGQTVMNTD 1107 + R+ +F +E +S+ P A+ DS P+G ++T+ Sbjct: 420 EQLWEVQRIITQLKRKLRTFEKKQEKTAEEVDNSSSAPPAVASEDTTDSKPAGTPAVSTN 479 Query: 1108 GSCRWSQSLPAASATT 1155 S SQ P T Sbjct: 480 NSI--SQEEPKTDTLT 493
>Q8N392:RHG18_HUMAN Rho GTPase-activating protein 18 - Homo sapiens (Human)| Length = 663 Score = 44.7 bits (104), Expect = 0.001 Identities = 47/202 (23%), Positives = 83/202 (41%), Gaps = 12/202 (5%) Frame = +1 Query: 205 EVQHVAHVTFDRFHGFLGLPVEFEPEVPRRAPSASASVFGVSTESMQCSYDSRGNSVPTI 384 +V H+A + + LG+ ++ + V + + ++ Q G +P I Sbjct: 286 KVCHLALIELTALYDVLGIELKQQKAVKIKTKDSGLFCVPLTALLEQDQRKVPGMRIPLI 345 Query: 385 LLMMQRRLYEQCGLRAEGIFRI-----NAENSQEELVRDRLNSGIVPYGIDVHCLSGLIK 549 + R+ E+ GL EG+ RI +N +EL + H + L+K Sbjct: 346 FQKLISRIEER-GLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHDAASLLK 404 Query: 550 AWFRELPSGVL--DPIPPEQVMQC-----QSEEDCARVAKCLPVAEAALLDWAVNLMADV 708 + RELP +L + + Q +Q Q + + LP A L + + V Sbjct: 405 LFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALLEFLQRV 464 Query: 709 VQEEKINKMNARNIAMVFAPNM 774 + ++ NKM N+AMV APN+ Sbjct: 465 IDNKEKNKMTVMNVAMVMAPNL 486
>Q8K0Q5:RHG18_MOUSE Rho GTPase-activating protein 18 - Mus musculus (Mouse)| Length = 663 Score = 44.3 bits (103), Expect = 0.001 Identities = 47/187 (25%), Positives = 80/187 (42%), Gaps = 15/187 (8%) Frame = +1 Query: 259 LPVEFEPEVPRRAPSASASVFGVSTESMQCSYDSR---GNSVPTILLMMQRRLYEQCGLR 429 L +EF+ + + + + +FG+ ++ D R G +P I + R+ E+ L Sbjct: 302 LGLEFKQQKAVKIKTRDSGLFGIPL-TILLEQDQRKVPGTRIPLIFQKLISRI-EEGSLE 359 Query: 430 AEGIFRI-----NAENSQEELVRDRLNSGIVPYGIDVHCLSGLIKAWFRELPSGVLD--- 585 EG+ RI +N +EL + H + L+K + RELP +L Sbjct: 360 TEGLLRIPGAAMRIKNLCQELEAKFYEGTFNWESVKQHDAASLLKLFLRELPQPLLSMEY 419 Query: 586 --PIPPEQVMQCQSEEDCAR--VAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIA 753 Q + + E+ A + LP A L + + V+ ++ NKM A N+A Sbjct: 420 LKAFQAVQNLPTRKEQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTAGNVA 479 Query: 754 MVFAPNM 774 MV APN+ Sbjct: 480 MVMAPNL 486
>P98171:RHG04_HUMAN Rho GTPase-activating protein 4 - Homo sapiens (Human)| Length = 946 Score = 43.9 bits (102), Expect = 0.002 Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 12/175 (6%) Frame = +1 Query: 286 PRRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENS 465 PR + + +FG E S G VP ++ R + GL+ EGIFR++ Sbjct: 494 PRPSSQYNQRLFGGDMEKF---IQSSGQPVPLVVESCIRFINLN-GLQHEGIFRVSGAQL 549 Query: 466 QEELVRDRLNSGIVPY-----GIDVHCLSGLIKAWFRELPSGVLDP-------IPPEQVM 609 + +RD G P D+ ++G++K +FR L + P E Sbjct: 550 RVSEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEA 609 Query: 610 QCQSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM 774 + E +R+ LP +L + + + Q N M+ N+A+ F P + Sbjct: 610 TAERVEHVSRLLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGPTL 664
>Q14CB8:RHG19_HUMAN Rho GTPase-activating protein 19 - Homo sapiens (Human)| Length = 494 Score = 43.5 bits (101), Expect = 0.002 Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 28/150 (18%) Frame = +1 Query: 409 YEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYGIDVHCLSG---------LIKAWFR 561 Y LR EG+FR+ + +++++RD LN+ G D+ SG L+K + Sbjct: 131 YLHKNLRVEGLFRVPGNSVRQQILRDALNN-----GTDIDLESGEFHSNDVATLLKMFLG 185 Query: 562 ELPSGVLD------PIPPEQVMQCQSEEDCARVAK-------------CLPVAEAALLDW 684 ELP +L + +MQ + + + LP LL Sbjct: 186 ELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKL 245 Query: 685 AVNLMADVVQEEKINKMNARNIAMVFAPNM 774 ++L+ +++ NKM+A N+A++FAP++ Sbjct: 246 LLDLLYQTAKKQDKNKMSAYNLALMFAPHV 275
>Q9P2N2:RHG28_HUMAN Rho GTPase-activating protein 28 - Homo sapiens (Human)| Length = 729 Score = 43.1 bits (100), Expect = 0.003 Identities = 47/208 (22%), Positives = 91/208 (43%), Gaps = 18/208 (8%) Frame = +1 Query: 205 EVQHVAHVTFDRFHGFLGLPVEFEPEVPRRAPSASASVFGVSTESMQCSYDSR--GNSVP 378 +++H++ + F G ++ + + +FGV + + G VP Sbjct: 342 KIRHLSLIELTAFFDAFG--IQLKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDPGVKVP 399 Query: 379 TILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLNS--GIVPYGIDVHC---LSGL 543 +L ++ E+ GL +EGIFR++ ++ + R+ L++ + D C + + Sbjct: 400 LVLQKFFEKV-EESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHREAAVM 458 Query: 544 IKAWFRELPSGV--LDPIP---------PEQVMQCQSEEDCARVAKCLPVAEAALLDWAV 690 +KA+FRELP+ + ++ IP P +Q Q+ + LP A + Sbjct: 459 LKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQA---LHLMVMALPDANRDAAQALM 515 Query: 691 NLMADVVQEEKINKMNARNIAMVFAPNM 774 V+ E N+M+ NI+ V APN+ Sbjct: 516 TFFNKVIANESKNRMSLWNISTVMAPNL 543
>Q6IFT4:RHG20_MOUSE Rho GTPase-activating protein 20 - Mus musculus (Mouse)| Length = 1182 Score = 41.6 bits (96), Expect = 0.009 Identities = 38/163 (23%), Positives = 77/163 (47%), Gaps = 10/163 (6%) Frame = +1 Query: 316 VFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLN 495 +FGVS + C D+ + +L + ++ G +GIFR +A ++++LN Sbjct: 362 LFGVSLPDL-CENDNLPKPILDMLSFLNQK-----GPLTKGIFRQSANMKSCRELKEKLN 415 Query: 496 SGIVPYGID---VHCLSGLIKAWFRELPSGVLDPIPPEQ---VMQCQSEED----CARVA 645 SGI + +D + ++ ++K + R +P + + VM ++E+ R+ Sbjct: 416 SGIEVH-LDCESIFVIASVLKDFLRNIPESIFSSDLYDHWVCVMDQGNDEEKINIIQRLL 474 Query: 646 KCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM 774 LP A L + ++ ++ Q N+M A N+A+ AP++ Sbjct: 475 DQLPRANVVFLRYLFGVLHNIEQHSLSNQMTAFNLAVCIAPSI 517
>Q6INE5:RHG19_XENLA Rho GTPase-activating protein 19 - Xenopus laevis (African clawed| frog) Length = 507 Score = 41.6 bits (96), Expect = 0.009 Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 30/152 (19%) Frame = +1 Query: 409 YEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYGIDVHC-------LSGLIKAWFREL 567 Y LR EG+FRI + +++ ++D LNSG+ IDV ++ L+K + EL Sbjct: 128 YLHKNLRTEGLFRIPGNSIRQQNLKDLLNSGM---DIDVESGEFHPNDVATLLKMFLGEL 184 Query: 568 PSGVL-----------------------DPIPPEQVMQCQSEEDCARVAKCLPVAEAALL 678 P +L +P ++ + E + LP LL Sbjct: 185 PEPLLTHRHYIAHLKIANLMLFDAKGNRTGVPDKE----RQIEALQLLFLLLPSPNRNLL 240 Query: 679 DWAVNLMADVVQEEKINKMNARNIAMVFAPNM 774 ++L+ +++ NKM+A N+A++FAP++ Sbjct: 241 KLLLDLLYQTARKQDRNKMSAHNLALMFAPHI 272
>Q9R0Z9:RHG07_MOUSE Rho GTPase-activating protein 7 - Mus musculus (Mouse)| Length = 1092 Score = 41.6 bits (96), Expect = 0.009 Identities = 42/164 (25%), Positives = 73/164 (44%), Gaps = 10/164 (6%) Frame = +1 Query: 313 SVFGVS-TESMQCSYDSRGNSVPTILLMMQRRLYEQCGL-RAEGI-FRINAENSQEELVR 483 SVFGV T ++Q S S+ + ++ +Q GL R G+ RI A E Sbjct: 638 SVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAE 697 Query: 484 DRLNSGIVPYGIDVHCLSGLIKAWFRELPSGVLDPIPPE---QVMQCQSEEDCARVAKC- 651 D +N G + ++ ++K +FR+LP ++ E Q+ Q ++ + K Sbjct: 698 DNVNYE----GQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAA 753 Query: 652 ---LPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM 774 LP +L + ++DV K N+M N+A+ AP++ Sbjct: 754 IMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 797
>Q96QB1:RHG07_HUMAN Rho GTPase-activating protein 7 - Homo sapiens (Human)| Length = 1091 Score = 41.6 bits (96), Expect = 0.009 Identities = 40/165 (24%), Positives = 74/165 (44%), Gaps = 11/165 (6%) Frame = +1 Query: 313 SVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRL 492 SVFGV + + G +P + R L C L G+FR + S+ + +R ++ Sbjct: 637 SVFGVP---LTVNVQRTGQPLPQSIQQAMRYLRNHC-LDQVGLFRKSGVKSRIQALR-QM 691 Query: 493 NSGIVPY----GIDVHCLSGLIKAWFRELPSGVLDPIPPE---QVMQCQSEEDCARVAKC 651 N G + G + ++ ++K +FR+LP ++ E Q+ Q ++ + K Sbjct: 692 NEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKA 751 Query: 652 ----LPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM 774 LP +L + ++DV K N+M N+A+ AP++ Sbjct: 752 AIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSL 796
>Q6REY9:RHG20_RAT Rho GTPase-activating protein 20 - Rattus norvegicus (Rat)| Length = 1182 Score = 41.2 bits (95), Expect = 0.011 Identities = 38/163 (23%), Positives = 77/163 (47%), Gaps = 10/163 (6%) Frame = +1 Query: 316 VFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLN 495 +FGVS + C D+ + +L + ++ G +GIFR +A ++++LN Sbjct: 362 LFGVSLPDI-CENDNLPKPILDMLSFLNQK-----GPLTKGIFRQSANMKSCRELKEKLN 415 Query: 496 SGIVPYGID---VHCLSGLIKAWFRELPSGVLDPIPPEQ---VMQCQSEED----CARVA 645 SGI + +D + ++ ++K + R +P + + VM ++E+ R+ Sbjct: 416 SGIEVH-LDCESIFVIASVLKDFLRNIPESIFSSDLYDHWVCVMDQGNDEEKINTIQRLL 474 Query: 646 KCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM 774 LP A L + ++ ++ Q N+M A N+A+ AP++ Sbjct: 475 DQLPRANVVFLRYLFGVLHNIEQHSLSNQMTAFNLAVCIAPSI 517
>Q8R5G7:CEND3_MOUSE Centaurin-delta 3 - Mus musculus (Mouse)| Length = 1538 Score = 41.2 bits (95), Expect = 0.011 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 12/134 (8%) Frame = +1 Query: 415 QCGLRAEGIFRINAENSQE-----ELVRDRLNSGIVPYGIDVHCLSGLIKAWFRELPSGV 579 Q GLR EG++R ++ E RD + + P V ++ +K +FREL V Sbjct: 928 QHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPREHFVEDVTDTLKRFFRELDDPV 987 Query: 580 LDP--IP-----PEQVMQCQSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMN 738 +P E + Q E V CLP L + + V + +N+M Sbjct: 988 TSARLLPRWREAAELSQKNQRLEKYKEVISCLPRVNRRTLATLIGHLYRVQKCASLNQMC 1047 Query: 739 ARNIAMVFAPNMTQ 780 RN+A++FAP++ Q Sbjct: 1048 TRNLALLFAPSVFQ 1061
>Q9BRR9:RHG09_HUMAN Rho GTPase-activating protein 9 - Homo sapiens (Human)| Length = 750 Score = 40.8 bits (94), Expect = 0.015 Identities = 45/208 (21%), Positives = 88/208 (42%), Gaps = 35/208 (16%) Frame = +1 Query: 316 VFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVR---- 483 VFG ES+ C + G++VP+ L + + ++ GL +GI+R++ + + +R Sbjct: 539 VFGCQLESL-CQRE--GDTVPSFLRLCIAAV-DKRGLDVDGIYRVSGNLAVVQKLRFLVD 594 Query: 484 --------------------DRLNSGIVPYGIDVHCLSGLIKAWFRELPSGVLDP--IPP 597 RL+ + D+H ++G +K + RELP ++ P +P Sbjct: 595 RERAVTSDGRYVFPEQPGQEGRLDLDSTEWD-DIHVVTGALKLFLRELPQPLVPPLLLPH 653 Query: 598 EQVMQCQSE-EDC----ARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVF 762 + SE E C + +P L + + + V+ N+M N+ +VF Sbjct: 654 FRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVF 713 Query: 763 APNM----TQMADPLTALMYAVQVMNFL 834 P + + +DP +Y Q++ + Sbjct: 714 GPTLFRPEQETSDPAAHALYPGQLVQLM 741
>O43295:SRGP2_HUMAN SLIT-ROBO Rho GTPase-activating protein 3 - Homo sapiens (Human)| Length = 1099 Score = 40.0 bits (92), Expect = 0.025 Identities = 38/207 (18%), Positives = 83/207 (40%), Gaps = 16/207 (7%) Frame = +1 Query: 274 EPEVPRRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRIN 453 +P+ RR S + SM+ G ++P ++ R + GL+ +GIFR+ Sbjct: 486 KPQKMRRPRPLSVYSHKLFNGSMEAFIKDSGQAIPLVVESCIRYI-NLYGLQQQGIFRVP 544 Query: 454 AENSQEELVRDRLNSGIVPY-----GIDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQ-- 612 + +++ G P D++ ++G++K +FR G+ +P+ P++ Q Sbjct: 545 GSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFR----GLENPLFPKERFQDL 600 Query: 613 ---------CQSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFA 765 + ++ LP ++ + + + Q N M+ N+A+ F Sbjct: 601 ISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFG 660 Query: 766 PNMTQMADPLTALMYAVQVMNFLKMLI 846 P + + D + + +K +I Sbjct: 661 PTLMHIPDGQDPVSCQAHINEVIKTII 687
>Q7YQL5:OPHN1_PONPY Oligophrenin 1 - Pongo pygmaeus (Orangutan)| Length = 802 Score = 39.3 bits (90), Expect = 0.042 Identities = 34/163 (20%), Positives = 69/163 (42%), Gaps = 15/163 (9%) Frame = +1 Query: 406 LYEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYGIDVH-------CLSGLIKAWFRE 564 + E G++ EG++R N Q + + + P +D H ++ +K + R Sbjct: 396 IIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRN 455 Query: 565 LPSGVLD-PIPPEQVMQCQSEEDCARVAKC------LPVAEAALLDWAVNLMADVVQEEK 723 L V+ + E V +S+ R+ LP +L+ + + +V + K Sbjct: 456 LSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSK 515 Query: 724 INKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNF-LKMLIE 849 N M N+ ++F P + + + A M ++ N +++LIE Sbjct: 516 ENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIE 558
>Q7YQL6:OPHN1_PANTR Oligophrenin 1 - Pan troglodytes (Chimpanzee)| Length = 802 Score = 39.3 bits (90), Expect = 0.042 Identities = 34/163 (20%), Positives = 69/163 (42%), Gaps = 15/163 (9%) Frame = +1 Query: 406 LYEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYGIDVH-------CLSGLIKAWFRE 564 + E G++ EG++R N Q + + + P +D H ++ +K + R Sbjct: 396 IIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRN 455 Query: 565 LPSGVLD-PIPPEQVMQCQSEEDCARVAKC------LPVAEAALLDWAVNLMADVVQEEK 723 L V+ + E V +S+ R+ LP +L+ + + +V + K Sbjct: 456 LSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSK 515 Query: 724 INKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNF-LKMLIE 849 N M N+ ++F P + + + A M ++ N +++LIE Sbjct: 516 ENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIE 558
>O60890:OPHN1_HUMAN Oligophrenin 1 - Homo sapiens (Human)| Length = 802 Score = 39.3 bits (90), Expect = 0.042 Identities = 34/163 (20%), Positives = 69/163 (42%), Gaps = 15/163 (9%) Frame = +1 Query: 406 LYEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYGIDVH-------CLSGLIKAWFRE 564 + E G++ EG++R N Q + + + P +D H ++ +K + R Sbjct: 396 IIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRN 455 Query: 565 LPSGVLD-PIPPEQVMQCQSEEDCARVAKC------LPVAEAALLDWAVNLMADVVQEEK 723 L V+ + E V +S+ R+ LP +L+ + + +V + K Sbjct: 456 LSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSK 515 Query: 724 INKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNF-LKMLIE 849 N M N+ ++F P + + + A M ++ N +++LIE Sbjct: 516 ENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIE 558
>Q96P48:CEND2_HUMAN Centaurin-delta 2 - Homo sapiens (Human)| Length = 1210 Score = 39.3 bits (90), Expect = 0.042 Identities = 35/134 (26%), Positives = 59/134 (44%), Gaps = 12/134 (8%) Frame = +1 Query: 415 QCGLRAEGIFRINAENSQ-----EELVRDRLNSGIVPYGIDVHCLSGLIKAWFRELPSGV 579 QCGL +EGI+R + S+ E L +D + + V +S +K + R+LP G+ Sbjct: 743 QCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGL 802 Query: 580 LDPIPPEQVMQCQS----EEDCARVAKCL---PVAEAALLDWAVNLMADVVQEEKINKMN 738 ++ EE +R + L P A + ++ + V N+MN Sbjct: 803 FTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMN 862 Query: 739 ARNIAMVFAPNMTQ 780 N+A+VF P + Q Sbjct: 863 VHNLAIVFGPTLFQ 876
>Q9BE31:RHG12_MACFA Rho GTPase-activating protein 12 - Macaca fascicularis (Crab eating| macaque) (Cynomolgus monkey) Length = 847 Score = 38.9 bits (89), Expect = 0.055 Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 11/132 (8%) Frame = +1 Query: 412 EQCGLRAEGIFRINAENSQEELVRDRLNSGIV-----PYGIDVHCLSGLIKAWFRELPSG 576 E+ GL +GI+R++ + + +R +N D+H ++G +K +FRELP Sbjct: 682 EEYGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEP 741 Query: 577 VLDPIPPEQVMQCQSEEDCARVA------KCLPVAEAALLDWAVNLMADVVQEEKINKMN 738 + + +E RVA + LP + + VV+ + N+M Sbjct: 742 LFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLKRVVENGEKNRMT 801 Query: 739 ARNIAMVFAPNM 774 ++IA+VF P + Sbjct: 802 YQSIAIVFGPTL 813
>O75044:FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating protein 2 - Homo sapiens (Human)| Length = 1071 Score = 38.9 bits (89), Expect = 0.055 Identities = 33/164 (20%), Positives = 71/164 (43%), Gaps = 16/164 (9%) Frame = +1 Query: 403 RLYEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYG-----IDVHCLSGLIKAWFREL 567 R + GL+ EGIFR++ + +++ G P D+ ++G++K +FR Sbjct: 513 RFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFR-- 570 Query: 568 PSGVLDPIPPEQV----MQCQSEED-------CARVAKCLPVAEAALLDWAVNLMADVVQ 714 G+ P+ P+ + M C + ++ +V LP ++ + + + Q Sbjct: 571 --GLEHPLFPKDIFHDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQ 628 Query: 715 EEKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLI 846 + N M+ N+A+ F P++ + + + V +K +I Sbjct: 629 FSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQAHVNELIKTII 672
>Q8WWN8:CEND3_HUMAN Centaurin-delta 3 - Homo sapiens (Human)| Length = 1544 Score = 38.9 bits (89), Expect = 0.055 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 12/134 (8%) Frame = +1 Query: 415 QCGLRAEGIFRINAENSQE-----ELVRDRLNSGIVPYGIDVHCLSGLIKAWFRELPSGV 579 Q GLR EG++R ++ E RD + + P V ++ +K +FREL V Sbjct: 932 QHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGEHFVEDVTDTLKRFFRELDDPV 991 Query: 580 LDP--IP-----PEQVMQCQSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMN 738 +P E + Q E V CLP L + + V + +N+M Sbjct: 992 TSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRRTLATLIGHLYRVQKCAALNQMC 1051 Query: 739 ARNIAMVFAPNMTQ 780 RN+A++FAP++ Q Sbjct: 1052 TRNLALLFAPSVFQ 1065
>Q812A2:SRGP2_MOUSE SLIT-ROBO Rho GTPase-activating protein 3 - Mus musculus (Mouse)| Length = 1099 Score = 38.5 bits (88), Expect = 0.072 Identities = 44/209 (21%), Positives = 84/209 (40%), Gaps = 18/209 (8%) Frame = +1 Query: 274 EPEVPRRAPSASASVFGVSTESMQCSYDSRGNSVPTILLMMQR--RLYEQCGLRAEGIFR 447 +P+ RR S + SM+ G ++P + R LY GL+ +GIFR Sbjct: 486 KPQKMRRPRPLSVYSHKLFNGSMEAFIKDSGQAIPLVAESCIRFINLY---GLQQQGIFR 542 Query: 448 INAENSQEELVRDRLNSGIVPY-----GIDVHCLSGLIKAWFRELPSGVLDPIPPEQVMQ 612 + + +++ G P D++ ++G++K +FR G+ +P+ P++ Q Sbjct: 543 VPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFR----GLENPLFPKERFQ 598 Query: 613 -----CQSEEDCARVAKC------LPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMV 759 + E RV LP ++ + + + Q N M+ N+A+ Sbjct: 599 DLISTIKLENPADRVHPIQQILITLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAIC 658 Query: 760 FAPNMTQMADPLTALMYAVQVMNFLKMLI 846 F P + + D + V +K +I Sbjct: 659 FGPTLMHIPDGQDPVSCQAHVNEVIKTII 687
>P26450:P85A_MOUSE Phosphatidylinositol 3-kinase regulatory subunit alpha - Mus| musculus (Mouse) Length = 724 Score = 38.5 bits (88), Expect = 0.072 Identities = 39/164 (23%), Positives = 73/164 (44%), Gaps = 17/164 (10%) Frame = +1 Query: 385 LLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYG---IDVHCLSGLIKAW 555 LL+ E+ GL ++R + ++ EL R L+ IDVH L+ K + Sbjct: 131 LLIKLLEAIEKKGLECSTLYRTQSSSNPAEL-RQLLDCDAASVDLEMIDVHVLADAFKRY 189 Query: 556 FRELPSGVLDPIPPEQVM----QCQSEEDCARVAKCL------PVAEAALLDWAVNLMAD 705 +LP+ V+ ++M + QS EDC ++ K L P L + + Sbjct: 190 LADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFK 249 Query: 706 VVQEEKINKMNARNIAMVFAPNMTQM----ADPLTALMYAVQVM 825 + Q N +NAR ++ +F+P + + +D L+ A++++ Sbjct: 250 LSQASSKNLLNARVLSEIFSPVLFRFPAASSDNTEHLIKAIEIL 293
>Q63744:RHG07_RAT Rho GTPase-activating protein 7 - Rattus norvegicus (Rat)| Length = 1091 Score = 38.1 bits (87), Expect = 0.094 Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 11/165 (6%) Frame = +1 Query: 313 SVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRL 492 SVFGV + + G +P + R L C L G+FR + S+ + +R ++ Sbjct: 637 SVFGVP---LTVNVQRSGQPLPQSIQQAMRYLRNHC-LDQVGLFRKSGVKSRIQALR-QM 691 Query: 493 NSGIVPY----GIDVHCLSGLIKAWFRELPSGVLDPIPPE---QVMQCQSEEDCARVAKC 651 N Y G + ++ ++K +FR+LP ++ E Q+ Q ++ + K Sbjct: 692 NESAEDYVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKA 751 Query: 652 ----LPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNM 774 LP +L + ++ V K N+M N+A+ AP++ Sbjct: 752 AIMLLPDENREVLQTLLYFLSHVTAAVKENQMTPTNLAVCLAPSL 796
>Q8IWW6:RHG12_HUMAN Rho GTPase-activating protein 12 - Homo sapiens (Human)| Length = 846 Score = 37.7 bits (86), Expect = 0.12 Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 11/132 (8%) Frame = +1 Query: 412 EQCGLRAEGIFRINAENSQEELVRDRLNSGIV-----PYGIDVHCLSGLIKAWFRELPSG 576 E+ GL +GI+R++ + + +R +N D+H ++G +K +FRELP Sbjct: 681 EEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEP 740 Query: 577 VLDPIPPEQVMQCQSEEDCARVA------KCLPVAEAALLDWAVNLMADVVQEEKINKMN 738 + + +E RVA + LP + + V++ + N+M Sbjct: 741 LFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMT 800 Query: 739 ARNIAMVFAPNM 774 ++IA+VF P + Sbjct: 801 YQSIAIVFGPTL 812
>P08855:ICAL_RABIT Calpastatin - Oryctolagus cuniculus (Rabbit)| Length = 718 Score = 37.7 bits (86), Expect = 0.12 Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 8/107 (7%) Frame = +1 Query: 850 KTLKDREESNLDDVSLSQKDPSDENGHHNPGFAVDSHRAEG------SRRPSSFSEEPLL 1011 KT ++ +S V +K + H + H ++G + + +S S+EP+ Sbjct: 32 KTEPEKSQSTKPPVDHEKKAQEGKPKEHTKPKSTHKHASDGEGKHGRNEKTASRSKEPVT 91 Query: 1012 NSPAHSTEDKPNEANPAGGDSAPSGQTVM--NTDGSCRWSQSLPAAS 1146 + E KP + PAGG S +G T + +SLPAA+ Sbjct: 92 PAKRTEPETKPQDTKPAGGKSVAAGTTAAPGKAGDPKKEKKSLPAAA 138
>Q91Z67:FNBP2_MOUSE SLIT-ROBO Rho GTPase-activating protein 2 - Mus musculus (Mouse)| Length = 1071 Score = 37.0 bits (84), Expect = 0.21 Identities = 32/164 (19%), Positives = 71/164 (43%), Gaps = 16/164 (9%) Frame = +1 Query: 403 RLYEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYG-----IDVHCLSGLIKAWFREL 567 R + GL+ EGIFR++ + +++ G P D+ ++G++K +FR Sbjct: 513 RFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFR-- 570 Query: 568 PSGVLDPIPPEQV----MQCQSEED-------CARVAKCLPVAEAALLDWAVNLMADVVQ 714 G+ P+ P+ + + C + ++ +V LP ++ + + + Q Sbjct: 571 --GLEHPLFPKDIFHDLIACVTMDNLQERAVHIRKVLLVLPKPTLIIMRYLFAFLNHLSQ 628 Query: 715 EEKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLI 846 + N M+ N+A+ F P++ + + + V +K +I Sbjct: 629 FSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQAHVNELIKTII 672
>Q8C0D4:RHG12_MOUSE Rho GTPase-activating protein 12 - Mus musculus (Mouse)| Length = 838 Score = 36.6 bits (83), Expect = 0.27 Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 11/132 (8%) Frame = +1 Query: 412 EQCGLRAEGIFRINAENSQEELVRDRLNSGIV-----PYGIDVHCLSGLIKAWFRELPSG 576 E+ GL +GI+R++ + + +R +N D+H ++G +K +FRELP Sbjct: 673 EEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEP 732 Query: 577 VLDPIPPEQVMQCQSEEDCARVA------KCLPVAEAALLDWAVNLMADVVQEEKINKMN 738 + + +E RV + LP + + V++ + N+M Sbjct: 733 LFTFNHFNDFVNAIKQEPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMT 792 Query: 739 ARNIAMVFAPNM 774 ++IA+VF P + Sbjct: 793 YQSIAIVFGPTL 804
>O43182:RHG06_HUMAN Rho GTPase-activating protein 6 - Homo sapiens (Human)| Length = 974 Score = 36.2 bits (82), Expect = 0.36 Identities = 35/142 (24%), Positives = 60/142 (42%), Gaps = 21/142 (14%) Frame = +1 Query: 412 EQCGLRAEGIFRINAENSQEELVRDRLNSGI---VPYGIDVHCLSGLIKAWFRELPSGVL 582 E+ GL+ GIFR+ + + +R+ + GI + VH ++ L+K + R++P +L Sbjct: 422 EKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLL 481 Query: 583 DPI------------PPEQVMQCQ------SEEDCARVAKCLPVAEAALLDWAVNLMADV 708 P EQ+ Q +C + + L N+ D Sbjct: 482 TRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDG 541 Query: 709 VQEEKINKMNARNIAMVFAPNM 774 QE NKM + N+A +F PN+ Sbjct: 542 -QEVTGNKMTSLNLATIFGPNL 562
>P18890:K1688_RAT Protein KIAA1688 homolog - Rattus norvegicus (Rat)| Length = 101 Score = 36.2 bits (82), Expect = 0.36 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 4/82 (4%) Frame = +1 Query: 616 QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEK--INKMNARNIAMVFAPN--MTQM 783 +S E V LP +L + + + VQ I KM+ N+AMV APN Q Sbjct: 9 ESPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAITKMDVSNLAMVMAPNCLRCQS 68 Query: 784 ADPLTALMYAVQVMNFLKMLIE 849 DP + M+FL++LI+ Sbjct: 69 DDPRVIFENTRKEMSFLRVLIQ 90
>O54834:RHG06_MOUSE Rho GTPase-activating protein 6 - Mus musculus (Mouse)| Length = 987 Score = 35.8 bits (81), Expect = 0.47 Identities = 33/145 (22%), Positives = 62/145 (42%), Gaps = 24/145 (16%) Frame = +1 Query: 412 EQCGLRAEGIFRINAENSQEELVRDRLNSGI---VPYGIDVHCLSGLIKAWFRELPSGVL 582 E+ GL+ GIFR+ + + +R+ + G+ + VH ++ L+K + R++P Sbjct: 424 EKHGLQTVGIFRVGSSKKRVRQLREEFDRGVDVCLEEEHSVHDVAALLKEFLRDMP---- 479 Query: 583 DPIPPEQV-------MQCQSEEDCARVAKC---LPVAEAALLDWAVNLMADVV------- 711 DP+ ++ + + EE + LP L + ++ V Sbjct: 480 DPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNV 539 Query: 712 ----QEEKINKMNARNIAMVFAPNM 774 QE NKM + N+A +F PN+ Sbjct: 540 SKDGQEVTGNKMTSLNLATIFGPNL 564
>Q9WVM1:RGAP1_MOUSE Rac GTPase-activating protein 1 - Mus musculus (Mouse)| Length = 628 Score = 35.8 bits (81), Expect = 0.47 Identities = 58/249 (23%), Positives = 101/249 (40%), Gaps = 15/249 (6%) Frame = +1 Query: 334 ESMQCSYDSRGNS-VPTILLMMQRRLYEQCGLRAEGIFRINA-ENSQEELVRDRLNSGIV 507 E M + S+ + +P I++ + EQ GL G++RI+ + + +EL L V Sbjct: 349 EGMLADFVSQASPMIPAIVVSCVNEI-EQRGLTEAGLYRISGCDRTVKELKEKFLKVKTV 407 Query: 508 PYGI---DVHCLSGLIKAWFRELPSGVLDPIPPEQVMQCQ--SEEDCARVAKCLPVAEA- 669 P D+H + L+K + R L +L + M+ ++ED + A V+E Sbjct: 408 PLLSKVDDIHVICSLLKDFLRNLKEPLLTFWLSKAFMEAAEITDEDNSTAAMYQAVSELP 467 Query: 670 -ALLDWAVNLMADV--VQEEKINKMNARNIAMVFAPNMTQMA----DPLTALMYAVQVMN 828 A D LM + V + KM+ N+A VF P + DP+T + + Sbjct: 468 QANRDTLAFLMIHLQRVSQSPDTKMDIANLAKVFGPTIVAHTVPNPDPVTMFQDIKRQLK 527 Query: 829 FLKMLIEKTLKDREESNLDDVSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPL 1008 ++ L+ L+ + + D EN +DS R G+ P + + Sbjct: 528 VVERLLSLPLEYWNQFMMVD---------QEN--------IDSQRGNGNSTPRTPDVKVS 570 Query: 1009 LNSPAHSTE 1035 L P + E Sbjct: 571 LLGPVTTPE 579
>P21138:SERA_ENTHI Serine-rich 25 kDa antigen protein - Entamoeba histolytica| Length = 233 Score = 35.4 bits (80), Expect = 0.61 Identities = 27/113 (23%), Positives = 49/113 (43%) Frame = +1 Query: 847 EKTLKDREESNLDDVSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAH 1026 E + D+ E++ D ++ + S + N A S + + +P + S + N P Sbjct: 92 EASSSDKPEASSSDKPDNKPEASSSDKPDNKPEASSSDKPDN--KPEASSSDKPDNKPEA 149 Query: 1027 STEDKPNEANPAGGDSAPSGQTVMNTDGSCRWSQSLPAASATTDISCATTLNS 1185 S+ DKP+ A + P + + S S + P AS+T ++T NS Sbjct: 150 SSSDKPDNKPEASSTNKPEASSTNKPEAS---STNKPEASSTNKPEASSTSNS 199
>Q9H0H5:RGAP1_HUMAN Rac GTPase-activating protein 1 - Homo sapiens (Human)| Length = 632 Score = 35.4 bits (80), Expect = 0.61 Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 14/158 (8%) Frame = +1 Query: 373 VPTILLMMQRRLYEQCGLRAEGIFRINA-ENSQEELVRDRLNSGIVPYGI---DVHCLSG 540 +P+I++ + EQ GL G++RI+ + + +EL L VP D+H + Sbjct: 362 IPSIVVHCVNEI-EQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420 Query: 541 LIKAWFRELPSGVLDPIPPEQVMQCQ--SEEDCARVAKCLPVAEA--ALLDWAVNLMADV 708 L+K + R L +L M+ ++ED + A V E A D LM + Sbjct: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480 Query: 709 --VQEEKINKMNARNIAMVFAPNMTQMA----DPLTAL 804 V + KM+ N+A VF P + A DP+T L Sbjct: 481 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTML 518
>O74335:RGA5_SCHPO Rho-GTPase-activating protein 5 - Schizosaccharomyces pombe| (Fission yeast) Length = 361 Score = 35.0 bits (79), Expect = 0.80 Identities = 29/142 (20%), Positives = 60/142 (42%), Gaps = 16/142 (11%) Frame = +1 Query: 412 EQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYG-------IDVHCLSGLIKAWFRELP 570 +Q + +GIFR+N + + ++++ ++G YG VH + + + + +P Sbjct: 79 KQNATQVKGIFRVNGSSKRIQILQKAFSTG-PDYGRSFDWEGYTVHDAANVFRRFINLMP 137 Query: 571 SGVL---------DPIPPEQVMQCQSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEK 723 V+ +P+ + + E R LP+ LL + ++L++ Sbjct: 138 EHVIPLEYYERFREPMTIPNLTDNERVEMYRRRIDELPIPNRQLLLYLLDLLSVFAMNSS 197 Query: 724 INKMNARNIAMVFAPNMTQMAD 789 N M A N+A +F P + D Sbjct: 198 KNLMTADNLAAIFQPGILSHPD 219
>Q9HF75:BEM2_ASHGO GTPase-activating protein BEM2 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 2071 Score = 35.0 bits (79), Expect = 0.80 Identities = 39/209 (18%), Positives = 84/209 (40%), Gaps = 21/209 (10%) Frame = +1 Query: 307 SASVFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRD 486 S +FGV E + + G +P I++ + + E GL G++R+ +++ Sbjct: 1866 SNKIFGVPVEDV---CEREGALIPNIIVKLLDEI-ELRGLDEVGLYRVPGSVGSINALKN 1921 Query: 487 RLNSGIVPYG---------IDVHCLSGLIKAWFRELPSG------------VLDPIPPEQ 603 + + +++ ++G K + RELP ++ + Sbjct: 1922 AFDDEGAVHNTFTLEDDRWFEINTIAGCFKLYLRELPESLFTNEKVDEFVNIMTAYKNHE 1981 Query: 604 VMQCQSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAPNMTQM 783 V Q + + LPV +L + V Q + N+M+A N+A+VF+ + Sbjct: 1982 VDLSQFQNGIKTLLSTLPVFNYHILKRLFLHLNRVHQHVENNRMDASNLAIVFSMSFINQ 2041 Query: 784 ADPLTALMYAVQVMNFLKMLIEKTLKDRE 870 D + + + L+ML++ +++ E Sbjct: 2042 DDLASTM---GPTLGLLQMLLQHLIRNPE 2067
>Q8ND99:CS016_HUMAN Uncharacterized protein C19orf16 - Homo sapiens (Human)| Length = 567 Score = 34.7 bits (78), Expect = 1.0 Identities = 19/49 (38%), Positives = 28/49 (57%) Frame = +2 Query: 227 SPLIGSMDSLGCPSSSSPRCLAALPAPVQVSLEFQQNQCSVPTIPEETV 373 +P I + +S+SPR +A+PAP Q + Q SVPTIP++ V Sbjct: 125 APAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAV 173
>P23253:TCNA_TRYCR Sialidase - Trypanosoma cruzi| Length = 1162 Score = 33.9 bits (76), Expect = 1.8 Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 4/84 (4%) Frame = +1 Query: 910 PSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSP----AHSTEDKPNEANPAGGDSA 1077 P+D + H P VDS P+ S ++P AHST P +++ G S Sbjct: 1047 PADSSAHSTPSTPVDSSAHSTPSTPADSSAHGTPSTPADSSAHSTPSTPADSSAHGTPST 1106 Query: 1078 PSGQTVMNTDGSCRWSQSLPAASA 1149 P+ D S + S PA S+ Sbjct: 1107 PA-------DSSAHSTPSTPAGSS 1123 Score = 33.5 bits (75), Expect = 2.3 Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 9/103 (8%) Frame = +1 Query: 910 PSDENGHHNPGFAVDS--HRAEGSRRPSSFSEEPL--LNSPAHSTEDKPNEANPAGGDSA 1077 P+D + H P VDS H + SS P +S AHST P +++ S Sbjct: 963 PADSSAHSTPSTPVDSSAHSTPSTPADSSAHSTPSTPADSSAHSTPSTPADSSAHSTPST 1022 Query: 1078 PSGQTVMNT-----DGSCRWSQSLPAASATTDISCATTLNSLH 1191 P + +T D S + S PA S+ +S H Sbjct: 1023 PVDSSAHSTPSTPADSSAHGTPSTPADSSAHSTPSTPVDSSAH 1065 Score = 32.7 bits (73), Expect = 4.0 Identities = 25/99 (25%), Positives = 38/99 (38%), Gaps = 5/99 (5%) Frame = +1 Query: 910 PSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAHSTEDKPNEANPAGGDSAPSGQ 1089 P+D + H P VDS P+ +S AH T P +++ G S P+ Sbjct: 891 PADSSAHSTPSTPVDSSAHSTPSTPA--------DSSAHGTPSTPVDSSAHGTPSTPADS 942 Query: 1090 TVMNT-----DGSCRWSQSLPAASATTDISCATTLNSLH 1191 + +T D S + S PA S+ +S H Sbjct: 943 SAHSTPSTPADSSAHSTPSTPADSSAHSTPSTPVDSSAH 981 Score = 32.3 bits (72), Expect = 5.2 Identities = 31/130 (23%), Positives = 48/130 (36%), Gaps = 9/130 (6%) Frame = +1 Query: 829 FLKMLIEKTLKDREESNLDDVSLSQKDPSDENGHHNPGFAVDS--HRAEGSRRPSSFSEE 1002 FL + T + S+ + P+D + H P VDS H + SS Sbjct: 576 FLSQDLIGTEAHMDSSSDSSAHSTPSTPADSSAHSTPSTPVDSSAHSTPSTPADSSAHGT 635 Query: 1003 PL--LNSPAHSTEDKPNEANPAGGDSAPSGQTVMNT-----DGSCRWSQSLPAASATTDI 1161 P ++S AH T P +++ G S P + +T D S + S P S+ Sbjct: 636 PSTPVDSSAHGTPSTPADSSAHGTPSTPVDSSAHSTPSTPVDSSAHSTPSTPVDSSAHGA 695 Query: 1162 SCATTLNSLH 1191 +S H Sbjct: 696 PSTPADSSAH 705 Score = 32.3 bits (72), Expect = 5.2 Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 9/103 (8%) Frame = +1 Query: 910 PSDENGHHNPGFAVDS--HRAEGSRRPSSFSEEPL--LNSPAHSTEDKPNEANPAGGDSA 1077 P+D + H P VDS H + SS P +S AHST P +++ S Sbjct: 915 PADSSAHGTPSTPVDSSAHGTPSTPADSSAHSTPSTPADSSAHSTPSTPADSSAHSTPST 974 Query: 1078 PSGQTVMNT-----DGSCRWSQSLPAASATTDISCATTLNSLH 1191 P + +T D S + S PA S+ +S H Sbjct: 975 PVDSSAHSTPSTPADSSAHSTPSTPADSSAHSTPSTPADSSAH 1017 Score = 32.3 bits (72), Expect = 5.2 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 5/85 (5%) Frame = +1 Query: 910 PSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAHSTEDKPNEANPAGGDSAPSGQ 1089 P+D + H P DS P ++S AHST P +++ G S P+ Sbjct: 1035 PADSSAHGTPSTPADSSAHSTPSTP--------VDSSAHSTPSTPADSSAHGTPSTPADS 1086 Query: 1090 TVMNT-----DGSCRWSQSLPAASA 1149 + +T D S + S PA S+ Sbjct: 1087 SAHSTPSTPADSSAHGTPSTPADSS 1111 Score = 32.0 bits (71), Expect = 6.8 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 5/99 (5%) Frame = +1 Query: 910 PSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAHSTEDKPNEANPAGGDSAPSGQ 1089 P+D + H P VDS A G+ PS+ ++ S AHST P +++ S P+ Sbjct: 699 PADSSAHGTPSTPVDS-SAHGT--PSTPAD-----SSAHSTPSTPADSSAHSTPSTPADS 750 Query: 1090 TVMNT-----DGSCRWSQSLPAASATTDISCATTLNSLH 1191 + +T D S + S PA S+ +S H Sbjct: 751 SAHSTPSTPVDSSAHGTPSTPADSSAHSTPSTPADSSAH 789 Score = 32.0 bits (71), Expect = 6.8 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 5/99 (5%) Frame = +1 Query: 910 PSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAHSTEDKPNEANPAGGDSAPSGQ 1089 P+D + H P VDS A G+ PS+ ++ S AHST P +++ G S P Sbjct: 747 PADSSAHSTPSTPVDS-SAHGT--PSTPAD-----SSAHSTPSTPADSSAHGTPSTPVDS 798 Query: 1090 TVMNT-----DGSCRWSQSLPAASATTDISCATTLNSLH 1191 + +T D S + S P S+ +S H Sbjct: 799 SAHSTPSTPVDSSAHGTPSTPVDSSAHSTPSTPVDSSAH 837 Score = 32.0 bits (71), Expect = 6.8 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 4/93 (4%) Frame = +1 Query: 910 PSDENGHHNPGFAVDS--HRAEGSRRPSSFSEEPL--LNSPAHSTEDKPNEANPAGGDSA 1077 P D + H P VDS H + SS P +S AHST P +++ G S Sbjct: 819 PVDSSAHSTPSTPVDSSAHGTPSTPVDSSAHSTPSTPADSSAHSTPSTPADSSAHGTPST 878 Query: 1078 PSGQTVMNTDGSCRWSQSLPAASATTDISCATT 1176 P + +T + S + S D S +T Sbjct: 879 PVDSSAHSTPSTPADSSAHSTPSTPVDSSAHST 911
>Q9NGB4:OSA_DROYA Trithorax group protein osa - Drosophila yakuba (Fruit fly)| Length = 324 Score = 33.9 bits (76), Expect = 1.8 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 7/89 (7%) Frame = +1 Query: 931 HNPGFAVDSHRAEGSRRPSSFSEEPL-------LNSPAHSTEDKPNEANPAGGDSAPSGQ 1089 H+ F + R + RP+S ++ + + A STE EA PA P+ Sbjct: 119 HSVEFRLLQQRQQQQLRPASAEKQAASAGGSAPVKAEAASTETSSTEAKPA-----PAAT 173 Query: 1090 TVMNTDGSCRWSQSLPAASATTDISCATT 1176 T + D + SQ LP A+ D+S ++T Sbjct: 174 TAVVNDENSNSSQQLPPAATFNDVSNSST 202
>Q6DID5:MUM1_MOUSE Mutated melanoma-associated antigen 1 - Mus musculus (Mouse)| Length = 682 Score = 33.9 bits (76), Expect = 1.8 Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 11/113 (9%) Frame = +1 Query: 718 EKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDREESNLDD-VS 894 E + K + NIA A A PL L Y + L +L E+T E ++D ++ Sbjct: 57 EALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERTSLSPESHPIEDGIT 116 Query: 895 LSQKDPSDE------NGHHNPGFAVDSHRAE----GSRRPSSFSEEPLLNSPA 1023 LSQK+ +D + +P + +A S+R S +S + LL S A Sbjct: 117 LSQKEKTDADVASQVSSAPSPSLLGEDGQAVVAQCASKRRSEYSSKSLLPSSA 169
>Q7Z6B7:SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating protein 1 - Homo sapiens (Human)| Length = 1085 Score = 33.1 bits (74), Expect = 3.0 Identities = 27/154 (17%), Positives = 64/154 (41%), Gaps = 12/154 (7%) Frame = +1 Query: 421 GLRAEGIFRINAENSQEELVRDRLNSGIVPY-----GIDVHCLSGLIKAWFRELPSGVLD 585 GL+ +GIFR++ + +++ G P D++ ++G++K +FR L + + Sbjct: 534 GLQHQGIFRVSGSQVEVNDIKNSFERGENPLADDQSNHDINSVAGVLKLYFRGLENPLFP 593 Query: 586 PIPPEQVMQC-------QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINKMNAR 744 ++ C + ++ LP + ++ + + + Q N M+ Sbjct: 594 KERFNDLISCIRIDNLYERALHIRKLLLTLPRSVLIVMRYLFAFLNHLSQYSDENMMDPY 653 Query: 745 NIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLI 846 N+A+ F P + + + + V +K +I Sbjct: 654 NLAICFGPTLMPVPEIQDQVSCQAHVNEIIKTII 687
>Q91Z69:SRGP1_MOUSE SLIT-ROBO Rho GTPase-activating protein 1 - Mus musculus (Mouse)| Length = 1062 Score = 32.7 bits (73), Expect = 4.0 Identities = 29/158 (18%), Positives = 69/158 (43%), Gaps = 16/158 (10%) Frame = +1 Query: 421 GLRAEGIFRINAENSQEELVRDRLNSGIVPY-----GIDVHCLSGLIKAWFRELPSGVLD 585 GL+ +GIFR++ + +++ G P D++ ++G++K +FR G+ + Sbjct: 511 GLQHQGIFRVSGSQVEVNDIKNSFERGENPLSDEQSNHDINSVAGVLKLYFR----GLEN 566 Query: 586 PIPPEQ----VMQC-------QSEEDCARVAKCLPVAEAALLDWAVNLMADVVQEEKINK 732 P+ P++ ++ C + ++ LP + ++ + + + Q N Sbjct: 567 PLFPKERFTDLISCIRIDNLYERALHIRKLLLTLPRSVLIVMRYLFAFLNHLSQYSDENM 626 Query: 733 MNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLI 846 M+ N+A+ F P + + + + V +K +I Sbjct: 627 MDPYNLAICFGPTLMPVPEIQDQVSCQAHVNEIVKTII 664
>O43052:RGA1_SCHPO Rho-type GTPase-activating protein 1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1150 Score = 32.7 bits (73), Expect = 4.0 Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 25/179 (13%) Frame = +1 Query: 436 GIFRINAENSQEELVRDRLNSGIVPYGIDVHC-----LSGLIKAWFRELPSGVLDPIPPE 600 G+FR N + + + D L+ + P ID L+ L+K + RELP DP+ Sbjct: 881 GVFRKNGNIRRLKELSDMLD--VSPDSIDYEQETPIQLAALLKKFLRELP----DPLLTF 934 Query: 601 QVM-------QCQSEEDCARVAKC----LPVAEAALLDWAVNLMADV-----VQEEKINK 732 ++ + +SEE+ RV LP ++ + V + +E +K Sbjct: 935 KLFGLFITSSKLESEEERMRVLHLTICLLPKGHRDTMEVIFGFLYWVASFSHIDDEVGSK 994 Query: 733 MNARNIAMVFAPNM--TQMADPLTALMYAVQVMNFLKMLIEKTLKDREESN--LDDVSL 897 M+ N+A V PN+ ++ DP+ A++ ++ L EK + E + LDD +L Sbjct: 995 MDIHNLATVITPNILYSKSNDPVDESFLAIEAVHLLIENFEKFCEVPREISLLLDDPTL 1053
>P40809:RG84C_DROME GTPase-activating protein RacGAP84C - Drosophila melanogaster| (Fruit fly) Length = 384 Score = 32.7 bits (73), Expect = 4.0 Identities = 40/154 (25%), Positives = 65/154 (42%), Gaps = 9/154 (5%) Frame = +1 Query: 412 EQCGLRAEGIFRINAENSQEELVRDRLNSG-IVPY--GIDVHCLSGLIKAWFRELPSGVL 582 E GL+ EG++R+++ + + +R +L G P+ D H L +K + R+L ++ Sbjct: 172 EARGLQQEGLYRVSSTREKCKRLRRKLLRGKSTPHLGNKDTHTLCCCVKDFLRQLVHPLI 231 Query: 583 DPIPPEQVMQCQSEED--CARVAKCLPVAEA--ALLDWAVNLMA--DVVQEEKINKMNAR 744 + ED +A L V E A D LM + E +M Sbjct: 232 PIYHRRDFEEATRHEDRLAVEMAVYLAVLELHQAHRDTLAYLMLHWQKIAESPAVRMTVN 291 Query: 745 NIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLI 846 N+A++FAP T D L V LK+L+ Sbjct: 292 NLAVIFAP--TLFGDLDLTLENVVTWQRVLKVLL 323
>P32784:GPT1_YEAST Glycerol-3-phosphate O-acyltransferase 1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 759 Score = 32.7 bits (73), Expect = 4.0 Identities = 27/90 (30%), Positives = 42/90 (46%) Frame = +1 Query: 823 MNFLKMLIEKTLKDREESNLDDVSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSSFSEE 1002 +N KML ++ +K R+E + +SQ+D D HHN DS +S S Sbjct: 621 LNRRKMLRKQKIK-RQEKDSSSPIISQRDNHDAYEHHNQ----DSDGVSLVNSDNSLSNI 675 Query: 1003 PLLNSPAHSTEDKPNEANPAGGDSAPSGQT 1092 PL +S H + +E++ A APS + Sbjct: 676 PLFSSTFH----RKSESSLASTSVAPSSSS 701
>Q16676:FOXD1_HUMAN Forkhead box protein D1 - Homo sapiens (Human)| Length = 465 Score = 32.7 bits (73), Expect = 4.0 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 6/79 (7%) Frame = +1 Query: 868 EESNLD------DVSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAHS 1029 EE+++D D +++ DE G P AV + R RR S E+ L + Sbjct: 15 EETDIDVVGEGEDEEDEEEEDDDEGGGGGPRLAVPAQRRR--RRRSYAGEDELEDLEEEE 72 Query: 1030 TEDKPNEANPAGGDSAPSG 1086 +D A PAGG AP G Sbjct: 73 DDDDILLAPPAGGSPAPPG 91
>Q811F1:ZBT41_MOUSE Zinc finger and BTB domain-containing protein 41 - Mus musculus| (Mouse) Length = 908 Score = 32.3 bits (72), Expect = 5.2 Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 5/84 (5%) Frame = +1 Query: 847 EKTLKDREES-----NLDDVSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLL 1011 E T D +ES NL S S+K+ SD N +PG + AE S+E Sbjct: 265 EDTSDDEQESGDGSDNLHQES-SEKERSDRNDSEDPG---SEYNAEDEELEEEVSDED-- 318 Query: 1012 NSPAHSTEDKPNEANPAGGDSAPS 1083 + S +D E P GDSA S Sbjct: 319 SDTEQSDKDNDAEEEPEAGDSAGS 342
>O43561:LAT_HUMAN Linker for activation of T-cells family member 1 - Homo sapiens| (Human) Length = 262 Score = 32.3 bits (72), Expect = 5.2 Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 8/105 (7%) Frame = +1 Query: 916 DENGHHNPGFAV---DSHRAEGSRRPSSFS-EEPLLNSPAHSTEDKPNEAN-PAGGDSAP 1080 DE+ +HNPG+ V DS A + PS+ + P + A S E + N P G+SA Sbjct: 152 DEDDYHNPGYLVVLPDSTPATSTAAPSAPALSTPGIRDSAFSMESIDDYVNVPESGESAE 211 Query: 1081 SGQTVMNTDGSCRW---SQSLPAASATTDISCATTLNSLHVHGKG 1206 + + DGS + SQ L +A T+ + ++ + V +G Sbjct: 212 A-----SLDGSREYVNVSQELHPGAAKTEPAALSSQEAEEVEEEG 251
>Q6DE96:IWS1A_XENLA IWS1 homolog A - Xenopus laevis (African clawed frog)| Length = 836 Score = 32.3 bits (72), Expect = 5.2 Identities = 18/65 (27%), Positives = 31/65 (47%) Frame = +1 Query: 847 EKTLKDREESNLDDVSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAH 1026 ++ + D ++ + DDV + + E H G A DS S++PS EE A+ Sbjct: 274 KRAIIDSDDDDDDDVPVKRAASDSEEETHPKGKASDSEDEAPSKQPSDSEEETPAKVAAN 333 Query: 1027 STEDK 1041 +ED+ Sbjct: 334 DSEDE 338
>P27986:P85A_HUMAN Phosphatidylinositol 3-kinase regulatory subunit alpha - Homo| sapiens (Human) Length = 724 Score = 32.0 bits (71), Expect = 6.8 Identities = 40/183 (21%), Positives = 78/183 (42%), Gaps = 18/183 (9%) Frame = +1 Query: 274 EPEVPRR---APSASASVFGVSTESMQCSYDSRGNSVPTI---LLMMQRRLYEQCGLRAE 435 +P PR AP +S + V +++ + + P I LL+ E+ GL Sbjct: 88 KPRPPRPLPVAPGSSKTEADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECS 147 Query: 436 GIFRINAENSQEEL--VRDRLNSGIVPYGIDVHCLSGLIKAWFRELPSGVLDPIPPEQVM 609 ++R + ++ EL + D + IDVH L+ K + +LP+ V+ +++ Sbjct: 148 TLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMI 207 Query: 610 ----QCQSEEDCARVAK------CLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMV 759 + QS E+ ++ K +P L + + + Q N +NAR ++ + Sbjct: 208 SLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEI 267 Query: 760 FAP 768 F+P Sbjct: 268 FSP 270
>P23727:P85A_BOVIN Phosphatidylinositol 3-kinase regulatory subunit alpha - Bos taurus| (Bovine) Length = 724 Score = 32.0 bits (71), Expect = 6.8 Identities = 35/178 (19%), Positives = 78/178 (43%), Gaps = 13/178 (7%) Frame = +1 Query: 376 PTILLMMQRRLYEQCGLRAEGIFRINAENSQEELVRDRLNSGIVPYGI---DVHCLSGLI 546 P +L+ + + E+ GL ++R + ++ EL R L+ + DVH L+ Sbjct: 129 PPLLIKLVEAI-EKKGLECSTLYRTQSSSNPAEL-RQLLDCDTASLDLEMFDVHVLADAF 186 Query: 547 KAWFRELPSGVLDPIPPEQVM----QCQSEEDCARVAK------CLPVAEAALLDWAVNL 696 K + +LP+ V+ +++ + QS E+ ++ K +P L + + Sbjct: 187 KRYLLDLPNPVIPVAVSSELISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKH 246 Query: 697 MADVVQEEKINKMNARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDRE 870 + Q N +NAR ++ +F+P + + P + ++ +++LI +R+ Sbjct: 247 FFKLSQTSSKNLLNARVLSELFSPLLFRF--PAASSENTEHLIKIIEILISTEWNERQ 302
>Q68DN1:CB016_HUMAN Uncharacterized protein C2orf16 - Homo sapiens (Human)| Length = 1984 Score = 32.0 bits (71), Expect = 6.8 Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 4/89 (4%) Frame = +1 Query: 835 KMLIEKTLKDREESNLDDVSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSSF----SEE 1002 + + E++ E+S+L + S+ PS+ GH + G S R PS + E Sbjct: 1839 RRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSE 1898 Query: 1003 PLLNSPAHSTEDKPNEANPAGGDSAPSGQ 1089 S T P+E P PSG+ Sbjct: 1899 RSHRSSCERTRHSPSEMRP----GRPSGR 1923
>Q60795:NF2L2_MOUSE Nuclear factor erythroid 2-related factor 2 - Mus musculus (Mouse)| Length = 597 Score = 31.6 bits (70), Expect = 8.8 Identities = 20/52 (38%), Positives = 23/52 (44%) Frame = +1 Query: 925 GHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAHSTEDKPNEANPAGGDSAP 1080 G PGF+ DS E P S + PAHS D +PA G SAP Sbjct: 358 GDPPPGFS-DSEMEELDSAPGSVKQNGPKAQPAHSPGDTVQPLSPAQGHSAP 408
>Q6P6Q6:MTER1_RAT mTERF domain-containing protein 1, mitochondrial precursor - Rattus| norvegicus (Rat) Length = 409 Score = 31.6 bits (70), Expect = 8.8 Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 2/105 (1%) Frame = +1 Query: 562 ELPSGVLDPIPPEQVMQCQSEEDCARVA--KCLPVAEAALLDWAVNLMADVVQEEKINKM 735 ELP LD +PP +Q SEE+ ++A LP++ + L D+ V E + K+ Sbjct: 99 ELPLEELDDLPPLSPLQPVSEEEAIQIAAYSPLPLSSSTLADY-------VDHSETLQKL 151 Query: 736 NARNIAMVFAPNMTQMADPLTALMYAVQVMNFLKMLIEKTLKDRE 870 + + +A+ L L + + L L + L+D + Sbjct: 152 VQLGVDLSKIEKHPDVANLLLRLNFEKDIKQILLFLKDLGLEDNQ 196
>P29362:LMP1_EBVC Latent membrane protein 1 - Epstein-Barr virus (strain Cao) (HHV-4)| (Human herpesvirus 4) Length = 404 Score = 31.6 bits (70), Expect = 8.8 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 6/82 (7%) Frame = +1 Query: 865 REESNLDDVSLSQKDPSDENGHHNPGFAVDSHRAEGSRRPSSFSEEPLLNSPAHSTED-- 1038 ++ N DD D +D+NG +P D+ + + +PL +SP+ S + Sbjct: 287 QDPDNTDDNGPQDPDNTDDNGPQDPDNTDDNGPQDPDNTDDNGPHDPLPHSPSDSAGNDG 346 Query: 1039 -KPN---EANPAGGDSAPSGQT 1092 PN E GGD P T Sbjct: 347 GPPNLTEEVANKGGDRGPPSMT 368
>P39960:BEM2_YEAST GTPase-activating protein BEM2/IPL2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 2167 Score = 31.6 bits (70), Expect = 8.8 Identities = 48/200 (24%), Positives = 84/200 (42%), Gaps = 26/200 (13%) Frame = +1 Query: 316 VFGVSTESMQCSYDSRGNSVPTILLMMQRRLYEQCGLRAEGIFRI-------NAENS--Q 468 +FGV E + + +PTI++ + + E GL G++RI NA + Sbjct: 1964 IFGVPLEDV---CERENTLIPTIVVKLLEEI-ELRGLDEVGLYRIPGSIGSINALKNAFD 2019 Query: 469 EELVRDRLNSGIVPYGIDVHCLSGLIKAWFRELPSGVLD--------PIPPEQVMQCQSE 624 EE D + +V+ ++G K + RELP + + + Sbjct: 2020 EEGATDNSFTLEDDRWFEVNAIAGCFKMYLRELPDSLFSHAMVNDFTDLAIKYKAHAMVN 2079 Query: 625 EDCARVA----KCLPVAEAALLDWAVNLMADVVQEEKINKMNARNIAMVFAP---NMTQM 783 E+ R+ + LP L V + V Q NKM+A N+A+VF+ N + Sbjct: 2080 EEYKRMMNELLQKLPTCYYQTLKRIVFHLNKVHQHVVNNKMDASNLAIVFSMSFINQEDL 2139 Query: 784 ADPLTALMYAVQ--VMNFLK 837 A+ + + + AVQ + +F+K Sbjct: 2140 ANSMGSRLGAVQTILQDFIK 2159 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.317 0.132 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 248,786,078 Number of extensions: 5583459 Number of successful extensions: 16775 Number of sequences better than 10.0: 114 Number of HSP's gapped: 16656 Number of HSP's successfully gapped: 127 Length of query: 487 Length of database: 100,686,439 Length adjustment: 117 Effective length of query: 370 Effective length of database: 68,593,924 Effective search space: 25379751880 Effective search space used: 25379751880 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
