ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf69k12 |
|---|---|
| Clone Library Name | barley_pub |
>P50218:IDHC_TOBAC Isocitrate dehydrogenase [NADP] - Nicotiana tabacum (Common tobacco)| Length = 415 Score = 727 bits (1877), Expect = 0.0 Identities = 344/410 (83%), Positives = 383/410 (93%), Gaps = 2/410 (0%) Frame = +3 Query: 174 MAFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTI 353 M F+KI+V NPIVEMDGDEMTR+IWK IKDKLI PFL+LDIKYFDLGLP+RDAT DKVT+ Sbjct: 1 MTFDKIKVENPIVEMDGDEMTRVIWKSIKDKLICPFLELDIKYFDLGLPHRDATDDKVTV 60 Query: 354 ESAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVP 533 ESAEAT KYNVAIKCAT+TPDE RVKEFNLK+MWRSPNGTIRNILNGTVFREPI+CKN+P Sbjct: 61 ESAEATQKYNVAIKCATITPDEARVKEFNLKSMWRSPNGTIRNILNGTVFREPIMCKNIP 120 Query: 534 RLVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF--DGIEEQIELDVFNFSGAGGV 707 RLVPGWTKPICIGRHAFGDQYRATD +I+G GKLKL+F +G +E+ E +V+NF+GAGGV Sbjct: 121 RLVPGWTKPICIGRHAFGDQYRATDTVIQGAGKLKLVFVPEGTDEKTEFEVYNFTGAGGV 180 Query: 708 ALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCR 887 ALSMYNTDES+R+FAEASMNMAYQK+WPLYLSTKNTILKKYDGRFKDIFQ+ YE NW+ + Sbjct: 181 ALSMYNTDESVRSFAEASMNMAYQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSK 240 Query: 888 FEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCP 1067 +E+AGIWYEHRLIDDM AYALKSEGGYVWACKNYDGDVQSD +AQGFGSLGLMTSVLVCP Sbjct: 241 YEEAGIWYEHRLIDDMAAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCP 300 Query: 1068 DGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQK 1247 DG+T+EAEAAHGTVTRHYRVHQKGGETSTNSIASIFAW+ GLAHRA LD+N+RLLDFT+K Sbjct: 301 DGKTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEK 360 Query: 1248 LEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRL 1397 LEAAC+G VESGKMTKDLAL+IHG +SRD YLNT EFIDAVA+EL+ RL Sbjct: 361 LEAACIGAVESGKMTKDLALIIHGSKLSRDHYLNTEEFIDAVADELKARL 410
>P50217:IDHC_SOLTU Isocitrate dehydrogenase [NADP] - Solanum tuberosum (Potato)| Length = 416 Score = 720 bits (1859), Expect = 0.0 Identities = 343/411 (83%), Positives = 383/411 (93%), Gaps = 3/411 (0%) Frame = +3 Query: 174 MAFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTI 353 MAF+KI V NPIVEMDGDEMTR+IWK IKDKLI PFL+LDIKYF LGLP+RDAT DKVT+ Sbjct: 1 MAFQKITVQNPIVEMDGDEMTRVIWKSIKDKLILPFLELDIKYFSLGLPHRDATDDKVTV 60 Query: 354 ESAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVP 533 ESAEAT KYNVAIKCAT+TPDE RVKEFNLK+MWRSPNGTIRNILNGTVFREPI+CKN+P Sbjct: 61 ESAEATQKYNVAIKCATITPDEARVKEFNLKSMWRSPNGTIRNILNGTVFREPIMCKNIP 120 Query: 534 RLVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF--DGIEEQIELDVFNFSGAGGV 707 RLVPGWTKPICIGRHAFGDQYRATD +I+G GKLKL+F +G +E+ E +V+NF+GAGGV Sbjct: 121 RLVPGWTKPICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGSDEKTEFEVYNFTGAGGV 180 Query: 708 ALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCR 887 ALSMYNTDES+R+FAEASMNMA+QK+WPLYLSTKNTILKKYDGRFKDIFQ+ YE NW+ + Sbjct: 181 ALSMYNTDESVRSFAEASMNMAFQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSK 240 Query: 888 FEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCP 1067 +E+AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSD +AQGFGSLGLMTSVLVCP Sbjct: 241 YEEAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCP 300 Query: 1068 DGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQK 1247 DG+T+EAEAAHGTVTRHYRVHQKGGETSTNSIASIFAW+ GLAHRA LD+N+RLLDFT+K Sbjct: 301 DGKTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEK 360 Query: 1248 LEAACVGTVESGKMTKDLAL-LIHGPTVSRDKYLNTMEFIDAVAEELRTRL 1397 LEAAC+G VESGKMTKDLAL +IHG +SR+ YLNT EFIDAVA+EL+ RL Sbjct: 361 LEAACIGAVESGKMTKDLALIIIHGSKLSREHYLNTEEFIDAVADELKARL 411
>Q40345:IDHP_MEDSA Isocitrate dehydrogenase [NADP], chloroplast precursor - Medicago| sativa (Alfalfa) Length = 433 Score = 717 bits (1850), Expect = 0.0 Identities = 341/416 (81%), Positives = 382/416 (91%), Gaps = 2/416 (0%) Frame = +3 Query: 162 TAAPMAFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGD 341 T A M F+KI+VANPIVEMDGDEMTRIIWK+IKDKLIFPF++LDIKYFDLGLP RD T D Sbjct: 18 TTATMGFQKIKVANPIVEMDGDEMTRIIWKYIKDKLIFPFVELDIKYFDLGLPYRDETND 77 Query: 342 KVTIESAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIIC 521 KVT+ESAEATLKYNVAIKCAT+TPDE RVKEF LK+MWRSPNGTIRNILNGTVFREPIIC Sbjct: 78 KVTVESAEATLKYNVAIKCATITPDEARVKEFGLKSMWRSPNGTIRNILNGTVFREPIIC 137 Query: 522 KNVPRLVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF--DGIEEQIELDVFNFSG 695 KN+PRL+PGWTKPICIGRHAFGDQYRATD +I+G GKLKL+F +G E +L+V+NF+G Sbjct: 138 KNIPRLIPGWTKPICIGRHAFGDQYRATDSVIKGPGKLKLVFVPEGQGETTDLEVYNFTG 197 Query: 696 AGGVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETN 875 GGVAL+MYNTDESIR+FAEASM +A +K+WPLYLSTKNTILKKYDGRFKDIFQ+ YE Sbjct: 198 EGGVALAMYNTDESIRSFAEASMAVALEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEAG 257 Query: 876 WRCRFEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSV 1055 W+ ++E AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSD +AQGFGSLGLMTSV Sbjct: 258 WKSKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSV 317 Query: 1056 LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLD 1235 LVCPDG+T+EAEAAHGTVTRH+RVHQKGGETSTNSIASIFAW+ GLAHRAKLDDN LLD Sbjct: 318 LVCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNATLLD 377 Query: 1236 FTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRLSA 1403 FT+KLEAAC+G VESGKMTKDLAL++HG +SR+ YLNT EFIDAVA EL+T++SA Sbjct: 378 FTEKLEAACIGVVESGKMTKDLALILHGSKLSREHYLNTEEFIDAVAAELKTKISA 433
>Q06197:IDHC_SOYBN Isocitrate dehydrogenase [NADP] - Glycine max (Soybean)| Length = 413 Score = 705 bits (1820), Expect = 0.0 Identities = 337/411 (81%), Positives = 376/411 (91%), Gaps = 2/411 (0%) Frame = +3 Query: 177 AFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIE 356 AF+KI+VANPIVEMDGDEMTR+IWK IKDKLI PFL+LDIKY+DLGLP RD T DKVTIE Sbjct: 3 AFQKIKVANPIVEMDGDEMTRVIWKSIKDKLILPFLELDIKYYDLGLPYRDETDDKVTIE 62 Query: 357 SAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPR 536 SAEATLKYNVAIKCAT+TPDE RVKEF LK+MW+SPNGTIRNILNGTVFREPI+CKN+PR Sbjct: 63 SAEATLKYNVAIKCATITPDEARVKEFGLKSMWKSPNGTIRNILNGTVFREPILCKNIPR 122 Query: 537 LVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF--DGIEEQIELDVFNFSGAGGVA 710 LVPGWTK ICIGRHAFGDQYRATD +I+G GKLKL+F +G E+ E +VFNF+G GGV+ Sbjct: 123 LVPGWTKAICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGQGEETEFEVFNFTGEGGVS 182 Query: 711 LSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRF 890 L+MYNTDESIR+FAEASM A +K+WPLYLSTKNTILKKYDGRFKDIFQ+ YE +W+ +F Sbjct: 183 LAMYNTDESIRSFAEASMATALEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKF 242 Query: 891 EDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPD 1070 E AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSD +AQGFGSLGLMTSVLVCPD Sbjct: 243 EAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPD 302 Query: 1071 GRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKL 1250 G+T+EAEAAHGTVTRH+RVHQKGGETSTNSIASIFAW+ GLAHRAKLDDN +LLDFT+KL Sbjct: 303 GKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNAKLLDFTEKL 362 Query: 1251 EAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRLSA 1403 EAAC+G VE+GKMTKDLAL++HG +SR+ YLNT EFIDAVA EL RLSA Sbjct: 363 EAACIGVVEAGKMTKDLALILHGSKLSREHYLNTEEFIDAVAAELSARLSA 413
>P33198:IDHP_PIG Isocitrate dehydrogenase [NADP], mitochondrial precursor - Sus scrofa| (Pig) Length = 421 Score = 565 bits (1456), Expect = e-160 Identities = 275/408 (67%), Positives = 327/408 (80%), Gaps = 5/408 (1%) Frame = +3 Query: 177 AFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIE 356 A ++I+VA P+VEMDGDEMTRIIW++IK+KLI P +D+ +KYFDLGLPNRD T D+VTI+ Sbjct: 9 ADQRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTID 68 Query: 357 SAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPR 536 SA AT KY+VA+KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFREPIICKN+PR Sbjct: 69 SALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPR 128 Query: 537 LVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGV 707 LVPGWTKPI IGRHA GDQY+ATD ++ G K++F DG + + +V+NF AGGV Sbjct: 129 LVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKIVFTPKDGSSAK-QWEVYNFP-AGGV 186 Query: 708 ALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCR 887 + MYNTDESI FA + A QK+WPLY+STKNTILK YDGRFKDIFQ+ +E +++ Sbjct: 187 GMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTD 246 Query: 888 FEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCP 1067 F+ IWYEHRLIDDMVA LKS GG+VWACKNYDGDVQSD++AQGFGSLGLMTSVLVCP Sbjct: 247 FDKYKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 306 Query: 1068 DGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQK 1247 DG+T+EAEAAHGTVTRHYR HQKG TSTN IASIFAW+ GL HR KLD N+ L+ F Q Sbjct: 307 DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQT 366 Query: 1248 LEAACVGTVESGKMTKDLALLIHGPTVSR--DKYLNTMEFIDAVAEEL 1385 LE CV TVESG MTKDLA IHG + + + +LNT +F+D + L Sbjct: 367 LEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNL 414
>Q04467:IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitochondrial precursor - Bos taurus| (Bovine) Length = 452 Score = 564 bits (1454), Expect = e-160 Identities = 276/408 (67%), Positives = 326/408 (79%), Gaps = 5/408 (1%) Frame = +3 Query: 177 AFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIE 356 A ++I+VA P+VEMDGDEMTRIIW++IK+KLI P +D+ +KYFDLGLPNRD T D+VTI+ Sbjct: 40 ADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTID 99 Query: 357 SAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPR 536 SA AT KY+VA+KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFREPIICKN+PR Sbjct: 100 SALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPR 159 Query: 537 LVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGV 707 LVPGWTKPI IGRHA GDQY+ATD ++ G K++F DG + E +V+NF AGGV Sbjct: 160 LVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPK-EWEVYNFP-AGGV 217 Query: 708 ALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCR 887 + MYNTDESI FA + A QK+WPLY+STKNTILK YDGRFKDIFQ +E +++ Sbjct: 218 GMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTE 277 Query: 888 FEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCP 1067 F+ IWYEHRLIDDMVA LKS GG+VWACKNYDGDVQSD++AQGFGSLGLMTSVLVCP Sbjct: 278 FDKHKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 337 Query: 1068 DGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQK 1247 DG+T+EAEAAHGTVTRHYR HQKG TSTN IASIFAW+ GL HR KLD N+ L+ F Q Sbjct: 338 DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQT 397 Query: 1248 LEAACVGTVESGKMTKDLALLIHGPTVSR--DKYLNTMEFIDAVAEEL 1385 LE CV TVESG MTKDLA IHG + + + +LNT +F+D + L Sbjct: 398 LEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNL 445
>P54071:IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitochondrial precursor - Mus| musculus (Mouse) Length = 524 Score = 563 bits (1451), Expect = e-159 Identities = 275/408 (67%), Positives = 326/408 (79%), Gaps = 5/408 (1%) Frame = +3 Query: 177 AFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIE 356 A ++I+V P+VEMDGDEMTRIIW++IK+KLI P +D+ +KYFDLGLPNRD T D+VTI+ Sbjct: 112 AEKRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTID 171 Query: 357 SAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPR 536 SA AT KY+VA+KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFREPIICKN+PR Sbjct: 172 SALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPR 231 Query: 537 LVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGV 707 LVPGWTKPI IGRHA GDQY+ATD ++ G KL+F DG + E +V+NF AGGV Sbjct: 232 LVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAK-EWEVYNFP-AGGV 289 Query: 708 ALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCR 887 + MYNTDESI FA + + QK+WPLYLSTKNTILK YDGRFKDIFQ+ ++ +++ Sbjct: 290 GMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTD 349 Query: 888 FEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCP 1067 F+ IWYEHRLIDDMVA LKS GG+VWACKNYDGDVQSD++AQGFGSLGLMTSVLVCP Sbjct: 350 FDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 409 Query: 1068 DGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQK 1247 DG+T+EAEAAHGTVTRHYR HQKG TSTN IASIFAW+ GL HR KLD N+ L+ F Q Sbjct: 410 DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQT 469 Query: 1248 LEAACVGTVESGKMTKDLALLIHGPTVSR--DKYLNTMEFIDAVAEEL 1385 LE CV TVESG MTKDLA IHG + + + +LNT +F+D + L Sbjct: 470 LEKVCVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNL 517
>Q4R502:IDHP_MACFA Isocitrate dehydrogenase [NADP], mitochondrial precursor - Macaca| fascicularis (Crab eating macaque) (Cynomolgus monkey) Length = 452 Score = 562 bits (1448), Expect = e-159 Identities = 275/408 (67%), Positives = 326/408 (79%), Gaps = 5/408 (1%) Frame = +3 Query: 177 AFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIE 356 A ++I+VA P+VEMDGDEMTRIIW++IK+KLI P +D+ +KYFDLGLPNRD T D+VTI+ Sbjct: 40 ADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTID 99 Query: 357 SAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPR 536 SA AT KY+VA+KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFREPIICKN+PR Sbjct: 100 SALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPR 159 Query: 537 LVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGV 707 LVPGWTKPI IGRHA GDQY+ATD + G K++F DG + E +V+NF AGGV Sbjct: 160 LVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVK-EWEVYNFP-AGGV 217 Query: 708 ALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCR 887 + MYNTDESI FA + A QK+WPLY+STKNTILK YDGRFKDIFQ+ ++ +++ Sbjct: 218 GMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTD 277 Query: 888 FEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCP 1067 F+ IWYEHRLIDDMVA LKS GG+VWACKNYDGDVQSD++AQGFGSLGLMTSVLVCP Sbjct: 278 FDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 337 Query: 1068 DGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQK 1247 DG+T+EAEAAHGTVTRHYR HQKG TSTN IASIFAW+ GL HR KLD N+ L+ F Q Sbjct: 338 DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQT 397 Query: 1248 LEAACVGTVESGKMTKDLALLIHGPTVSR--DKYLNTMEFIDAVAEEL 1385 LE CV TVESG MTKDLA IHG + + + +LNT +F+D + L Sbjct: 398 LEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNL 445
>P48735:IDHP_HUMAN Isocitrate dehydrogenase [NADP], mitochondrial precursor - Homo| sapiens (Human) Length = 452 Score = 562 bits (1448), Expect = e-159 Identities = 275/408 (67%), Positives = 326/408 (79%), Gaps = 5/408 (1%) Frame = +3 Query: 177 AFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIE 356 A ++I+VA P+VEMDGDEMTRIIW++IK+KLI P +D+ +KYFDLGLPNRD T D+VTI+ Sbjct: 40 ADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTID 99 Query: 357 SAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPR 536 SA AT KY+VA+KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFREPIICKN+PR Sbjct: 100 SALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPR 159 Query: 537 LVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGV 707 LVPGWTKPI IGRHA GDQY+ATD + G K++F DG + E +V+NF AGGV Sbjct: 160 LVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVK-EWEVYNFP-AGGV 217 Query: 708 ALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCR 887 + MYNTDESI FA + A QK+WPLY+STKNTILK YDGRFKDIFQ+ ++ +++ Sbjct: 218 GMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTD 277 Query: 888 FEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCP 1067 F+ IWYEHRLIDDMVA LKS GG+VWACKNYDGDVQSD++AQGFGSLGLMTSVLVCP Sbjct: 278 FDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 337 Query: 1068 DGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQK 1247 DG+T+EAEAAHGTVTRHYR HQKG TSTN IASIFAW+ GL HR KLD N+ L+ F Q Sbjct: 338 DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQM 397 Query: 1248 LEAACVGTVESGKMTKDLALLIHGPTVSR--DKYLNTMEFIDAVAEEL 1385 LE CV TVESG MTKDLA IHG + + + +LNT +F+D + L Sbjct: 398 LEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNL 445
>P56574:IDHP_RAT Isocitrate dehydrogenase [NADP], mitochondrial precursor - Rattus| norvegicus (Rat) Length = 452 Score = 561 bits (1447), Expect = e-159 Identities = 274/408 (67%), Positives = 326/408 (79%), Gaps = 5/408 (1%) Frame = +3 Query: 177 AFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIE 356 A ++I+V P+VEMDGDEMTRIIW++IK+KLI P +D+ +KYFDLGLPNRD T D+VTI+ Sbjct: 40 AEKRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTID 99 Query: 357 SAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPR 536 SA AT KY+VA+KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFREPIICKN+PR Sbjct: 100 SALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPR 159 Query: 537 LVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGV 707 LVPGWTKPI IGRHA GDQY+ATD ++ G KL+F DG + E +V+NF AGGV Sbjct: 160 LVPGWTKPITIGRHAHGDQYKATDFVVDRAGMFKLVFTPKDGSGAK-EWEVYNFP-AGGV 217 Query: 708 ALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCR 887 + MYNTDESI FA + + QK+WPLYLSTKNTI+K YDGRFKDIFQ+ ++ +++ Sbjct: 218 GMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTIMKAYDGRFKDIFQEIFDKHYKTD 277 Query: 888 FEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCP 1067 F+ IWYEHRLIDDMVA LKS GG+VWACKNYDGDVQSD++AQGFGSLGLMTSVLVCP Sbjct: 278 FDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 337 Query: 1068 DGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQK 1247 DG+T+EAEAAHGTVTRHYR HQKG TSTN IASIFAW+ GL HR KLD N+ L+ F Q Sbjct: 338 DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQT 397 Query: 1248 LEAACVGTVESGKMTKDLALLIHGPTVSR--DKYLNTMEFIDAVAEEL 1385 LE CV TVESG MTKDLA IHG + + + +LNT +F+D + L Sbjct: 398 LEKVCVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNL 445
>Q6XUZ5:IDHC_SHEEP Isocitrate dehydrogenase [NADP] cytoplasmic - Ovis aries (Sheep)| Length = 414 Score = 561 bits (1445), Expect = e-159 Identities = 275/414 (66%), Positives = 332/414 (80%), Gaps = 4/414 (0%) Frame = +3 Query: 186 KIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAE 365 KIQ +VEM GDEMTRIIW+ IK+KLIFP++DLD+ +DL + NRDAT D+VT ++AE Sbjct: 4 KIQ-GGSVVEMQGDEMTRIIWELIKEKLIFPYVDLDLHSYDLSIENRDATNDQVTKDAAE 62 Query: 366 ATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVP 545 A KYNV +KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFRE IICKN+PRLV Sbjct: 63 AIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122 Query: 546 GWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGVALS 716 GW KPI IGRHA+GDQYRATD ++ G GK+++ + DG + + L V NF+ +GGVA+ Sbjct: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEICYTPSDGSPKTVYL-VHNFTESGGVAMG 181 Query: 717 MYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFED 896 M+N D+SI FA +S MA K WPLYLSTKNTILKKYDGRFKDIFQ+ Y+ ++ +FE Sbjct: 182 MFNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEA 241 Query: 897 AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGR 1076 IWYEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDG+ Sbjct: 242 QNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGK 301 Query: 1077 TVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEA 1256 TVEAEAAHGTVTRHYR++QKG ETSTN IASIFAW+ GLAHRAKLD+NK L F + LE Sbjct: 302 TVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALEE 361 Query: 1257 ACVGTVESGKMTKDLALLIHG-PTVSRDKYLNTMEFIDAVAEELRTRLSAKSKL 1415 C+ T+E+G MTKDLA I G P V R YLNT EF+D + E L+ +L A++KL Sbjct: 362 VCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKL-AQAKL 414
>Q9XSG3:IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytoplasmic - Bos taurus (Bovine)| Length = 414 Score = 561 bits (1445), Expect = e-159 Identities = 275/415 (66%), Positives = 332/415 (80%), Gaps = 4/415 (0%) Frame = +3 Query: 183 EKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESA 362 +KIQ +VEM GDEMTRIIW+ IK+KLIFP+++LD+ +DLG+ NRDAT D+VT ++A Sbjct: 3 QKIQ-GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAA 61 Query: 363 EATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLV 542 EA KYNV +KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFRE IICKN+PRLV Sbjct: 62 EAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLV 121 Query: 543 PGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGVAL 713 GW KPI IGRHA+GDQYRATD ++ G GK+++ + DG + + L V NF+ +GGVA+ Sbjct: 122 SGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYL-VHNFTESGGVAM 180 Query: 714 SMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFE 893 MYN D+SI FA +S MA K WPLYLSTKNTILKKYDGRFKDIFQ+ Y+ ++ FE Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240 Query: 894 DAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDG 1073 IWYEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDG Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300 Query: 1074 RTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLE 1253 +TVEAEAAHGTVTRHYR++QKG ET TN IASIFAW+ GLAHRAKLD+NK L F + LE Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETLTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360 Query: 1254 AACVGTVESGKMTKDLALLIHG-PTVSRDKYLNTMEFIDAVAEELRTRLSAKSKL 1415 C+ T+E+G MTKDLA I G P V R YLNT EF+D + E L+ +L A++KL Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKL-AQAKL 414
>Q5R9C5:IDHC_PONPY Isocitrate dehydrogenase [NADP] cytoplasmic - Pongo pygmaeus| (Orangutan) Length = 414 Score = 557 bits (1435), Expect = e-158 Identities = 273/407 (67%), Positives = 326/407 (80%), Gaps = 4/407 (0%) Frame = +3 Query: 207 IVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAEATLKYNV 386 +VEM GDEMTRIIW+ IK+KLIFP+++LD+ +DLG+ NRDAT D+VT ++AEA KYNV Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNV 69 Query: 387 AIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVPGWTKPIC 566 +KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFRE IICKN+PRLV GW KPI Sbjct: 70 GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPII 129 Query: 567 IGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGVALSMYNTDES 737 IGRHA+GDQYRATD ++ G GK+++ + DG ++ L V NF GGVA+ MYN D+S Sbjct: 130 IGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYL-VHNFEEGGGVAMGMYNQDKS 188 Query: 738 IRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEH 917 I FA +S MA K WPLYLSTKNTILKKYDGRFKDIFQ+ Y+ ++ +FE IWYEH Sbjct: 189 IEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEARKIWYEH 248 Query: 918 RLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAA 1097 RLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDG+TVEAEAA Sbjct: 249 RLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAA 308 Query: 1098 HGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVE 1277 HGTVTRHYR++QKG ETSTN IASIFAW+ GLAHRAKLD+NK L F LE V T+E Sbjct: 309 HGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSVETIE 368 Query: 1278 SGKMTKDLALLIHG-PTVSRDKYLNTMEFIDAVAEELRTRLSAKSKL 1415 +G MTKDLA I G P V R YLNT EF+D + E L+ +L A++KL Sbjct: 369 AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL-AQAKL 414
>Q9Z2K9:IDHC_MICME Isocitrate dehydrogenase [NADP] cytoplasmic - Microtus mexicanus| (Mexican vole) Length = 414 Score = 557 bits (1435), Expect = e-158 Identities = 271/407 (66%), Positives = 326/407 (80%), Gaps = 4/407 (0%) Frame = +3 Query: 207 IVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAEATLKYNV 386 +VEM GDEMTRIIW+ IK+KLI P+++LD+ +DLG+ NRDAT D+VT ++AEA KYNV Sbjct: 10 VVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNV 69 Query: 387 AIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVPGWTKPIC 566 +KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFRE IICKN+PRLV GW KPI Sbjct: 70 GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPII 129 Query: 567 IGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGVALSMYNTDES 737 IGRHA+GDQYRATD ++ G GK+++ F DG ++ L V +F GGVA+ MYN D+S Sbjct: 130 IGRHAYGDQYRATDFVVPGPGKVEITFTPKDGSQKVTYL-VHSFEEGGGVAMGMYNQDKS 188 Query: 738 IRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEH 917 I FA +S MA K WPLYLSTKNTILKKYDGRFKDIFQ+ Y+ ++ +FE IWYEH Sbjct: 189 IEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEH 248 Query: 918 RLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAA 1097 RLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDG+TVEAEAA Sbjct: 249 RLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAA 308 Query: 1098 HGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVE 1277 HGTVTRHYR+HQKG ETSTN IASIFAWS GLAHRA+LD+N L F + LE C+ T+E Sbjct: 309 HGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIE 368 Query: 1278 SGKMTKDLALLIHG-PTVSRDKYLNTMEFIDAVAEELRTRLSAKSKL 1415 +G MTKDLA I G P V R YLNT EF+D + E L+ +L A++KL Sbjct: 369 AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL-AQAKL 414
>Q9Z2K8:IDHC_MICOH Isocitrate dehydrogenase [NADP] cytoplasmic - Microtus ochrogaster| (Prairie vole) Length = 414 Score = 556 bits (1432), Expect = e-157 Identities = 270/407 (66%), Positives = 326/407 (80%), Gaps = 4/407 (0%) Frame = +3 Query: 207 IVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAEATLKYNV 386 +VEM GDEMTRIIW+ IK+KLI P+++LD+ +DLG+ NRDAT D+VT ++AEA KYNV Sbjct: 10 VVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNV 69 Query: 387 AIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVPGWTKPIC 566 +KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFRE IICKN+PRLV GW KPI Sbjct: 70 GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPII 129 Query: 567 IGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGVALSMYNTDES 737 IGRHA+GDQYRATD ++ G GK+++ + DG ++ L V +F GGVA+ MYN D+S Sbjct: 130 IGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYL-VHSFEEGGGVAMGMYNQDKS 188 Query: 738 IRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEH 917 I FA +S MA K WPLYLSTKNTILKKYDGRFKDIFQ+ Y+ ++ +FE IWYEH Sbjct: 189 IEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEH 248 Query: 918 RLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAA 1097 RLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDG+TVEAEAA Sbjct: 249 RLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAA 308 Query: 1098 HGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVE 1277 HGTVTRHYR+HQKG ETSTN IASIFAWS GLAHRA+LD+N L F + LE C+ T+E Sbjct: 309 HGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIE 368 Query: 1278 SGKMTKDLALLIHG-PTVSRDKYLNTMEFIDAVAEELRTRLSAKSKL 1415 +G MTKDLA I G P V R YLNT EF+D + E L+ +L A++KL Sbjct: 369 AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL-AQAKL 414
>P41562:IDHC_RAT Isocitrate dehydrogenase [NADP] cytoplasmic - Rattus norvegicus (Rat)| Length = 414 Score = 555 bits (1429), Expect = e-157 Identities = 270/407 (66%), Positives = 325/407 (79%), Gaps = 4/407 (0%) Frame = +3 Query: 207 IVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAEATLKYNV 386 +VEM GDEMTRIIW+ IK+KLI P+++LD+ +DLG+ NRDAT D+VT ++AEA KYNV Sbjct: 10 VVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNV 69 Query: 387 AIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVPGWTKPIC 566 +KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFRE IICKN+PRLV GW KPI Sbjct: 70 GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPII 129 Query: 567 IGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGVALSMYNTDES 737 IGRHA+GDQYRATD ++ G GK+++ + DG ++ L V +F GGVA+ MYN D+S Sbjct: 130 IGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYL-VHDFEEGGGVAMGMYNQDKS 188 Query: 738 IRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEH 917 I FA +S MA K WPLYLSTKNTILKKYDGRFKDIFQ+ Y+ ++ +FE IWYEH Sbjct: 189 IEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFEAQKIWYEH 248 Query: 918 RLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAA 1097 RLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDG+TVEAEAA Sbjct: 249 RLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAA 308 Query: 1098 HGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVE 1277 HGTVTRHYR++QKG ETSTN IASIFAWS GLAHRAKLD+N L F LE C+ T+E Sbjct: 309 HGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALEEVCIETIE 368 Query: 1278 SGKMTKDLALLIHG-PTVSRDKYLNTMEFIDAVAEELRTRLSAKSKL 1415 +G MTKDLA I G P V R YLNT EF+D + E L+ +L A++KL Sbjct: 369 AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL-AQAKL 414
>O75874:IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic - Homo sapiens (Human)| Length = 414 Score = 555 bits (1429), Expect = e-157 Identities = 271/407 (66%), Positives = 326/407 (80%), Gaps = 4/407 (0%) Frame = +3 Query: 207 IVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAEATLKYNV 386 +VEM GDEMTRIIW+ IK+KLIFP+++LD+ +DLG+ NRDAT D+VT ++AEA K+NV Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNV 69 Query: 387 AIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVPGWTKPIC 566 +KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFRE IICKN+PRLV GW KPI Sbjct: 70 GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPII 129 Query: 567 IGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGVALSMYNTDES 737 IGRHA+GDQYRATD ++ G GK+++ + DG ++ L V NF GGVA+ MYN D+S Sbjct: 130 IGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYL-VHNFEEGGGVAMGMYNQDKS 188 Query: 738 IRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEH 917 I FA +S MA K WPLYLSTKNTILKKYDGRFKDIFQ+ Y+ ++ +FE IWYEH Sbjct: 189 IEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEH 248 Query: 918 RLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAA 1097 RLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDG+TVEAEAA Sbjct: 249 RLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAA 308 Query: 1098 HGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVE 1277 HGTVTRHYR++QKG ETSTN IASIFAW+ GLAHRAKLD+NK L F LE + T+E Sbjct: 309 HGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIE 368 Query: 1278 SGKMTKDLALLIHG-PTVSRDKYLNTMEFIDAVAEELRTRLSAKSKL 1415 +G MTKDLA I G P V R YLNT EF+D + E L+ +L A++KL Sbjct: 369 AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL-AQAKL 414
>O88844:IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic - Mus musculus (Mouse)| Length = 414 Score = 550 bits (1418), Expect = e-156 Identities = 271/414 (65%), Positives = 328/414 (79%), Gaps = 4/414 (0%) Frame = +3 Query: 186 KIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAE 365 KIQ +VEM GDEMTRIIW+ IK+KLI P+++LD+ +DLG+ NRDAT D+VT ++AE Sbjct: 4 KIQ-GGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAE 62 Query: 366 ATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVP 545 A KYNV +KCAT+TPDE RV+EF LK MW+SPNGTIRNIL GTVFRE IICKN+PRLV Sbjct: 63 AIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVT 122 Query: 546 GWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGVALS 716 GW KPI IGRHA+GDQYRATD ++ G GK+++ + DG ++ + V +F GGVA+ Sbjct: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQK-VTYMVHDFEEGGGVAMG 181 Query: 717 MYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFED 896 MYN D+SI FA +S MA K WPLYLSTKNTILKKYDGRFKDIFQ+ Y+ ++ +FE Sbjct: 182 MYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEA 241 Query: 897 AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGR 1076 I YEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDG+ Sbjct: 242 QNICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGK 301 Query: 1077 TVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEA 1256 TVEAEAAHGTVTRHYR++QKG ETSTN IASIFAWS GLAHRAKLD+N L F + LE Sbjct: 302 TVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALED 361 Query: 1257 ACVGTVESGKMTKDLALLIHG-PTVSRDKYLNTMEFIDAVAEELRTRLSAKSKL 1415 C+ T+E+G MTKDLA I G P V R YLNT EF+D + E L+ +L A++KL Sbjct: 362 VCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKL-AQAKL 414
>O14254:IDHP_SCHPO Probable isocitrate dehydrogenase [NADP], mitochondrial precursor -| Schizosaccharomyces pombe (Fission yeast) Length = 418 Score = 545 bits (1403), Expect = e-154 Identities = 260/414 (62%), Positives = 330/414 (79%), Gaps = 3/414 (0%) Frame = +3 Query: 165 AAPMAFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDK 344 A+ +F+KI V NP+VEMDGDEMTR+IWK I++KL+ P++D+ + Y+DLG+ RD T D+ Sbjct: 6 ASSKSFQKITVKNPVVEMDGDEMTRVIWKIIREKLVLPYMDIKLDYYDLGIEARDKTNDQ 65 Query: 345 VTIESAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICK 524 +T+++A+A LK +V IKCAT+TPDE RVKE+NLK MW+SPNGTIRNILNGTVFREPI+ K Sbjct: 66 ITVDAAKAILKNDVGIKCATITPDEARVKEYNLKKMWKSPNGTIRNILNGTVFREPILIK 125 Query: 525 NVPRLVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIFD---GIEEQIELDVFNFSG 695 N+P+ +PGWT PICIGRHAFGDQY++TD++ G GKL+L F + +V+ F+G Sbjct: 126 NIPKYIPGWTNPICIGRHAFGDQYKSTDLVASGPGKLELSFTPKGNPSAKETYNVYEFNG 185 Query: 696 AGGVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETN 875 +G VA+SMYNTD+SIR FA +S MA QK+ PLYLSTKNTILKKYDGRFKD FQ+ YE++ Sbjct: 186 SG-VAMSMYNTDDSIRGFAHSSFQMALQKKMPLYLSTKNTILKKYDGRFKDTFQEVYESD 244 Query: 876 WRCRFEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSV 1055 ++ +FE+ G+WY+HRLIDDMVA A+KS GG+VWACKNYDGDV SD++AQ +GSLGLMTSV Sbjct: 245 YKQKFEELGLWYQHRLIDDMVAQAIKSNGGFVWACKNYDGDVMSDVVAQAYGSLGLMTSV 304 Query: 1056 LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLD 1235 L+ P+GRT E+EAAHGTV RHY + KG +TSTNSIASIFAW+ GLAHR +LD N+RL+ Sbjct: 305 LIHPNGRTFESEAAHGTVQRHYMQYLKGKKTSTNSIASIFAWTRGLAHRGRLDGNERLVK 364 Query: 1236 FTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRL 1397 F LE ACV VE G MTKDL LL P + Y++T EF+DAV EL + L Sbjct: 365 FANALEHACVRCVEKGIMTKDLYLLSKSP----NGYVDTFEFLDAVKSELDSEL 414
>O13285:IDH1_CANTR Isocitrate dehydrogenase [NADP], mitochondrial precursor - Candida| tropicalis (Yeast) Length = 430 Score = 525 bits (1352), Expect = e-148 Identities = 268/413 (64%), Positives = 325/413 (78%), Gaps = 4/413 (0%) Frame = +3 Query: 162 TAAPMAFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGD 341 T+A +A +KI+V NPIVE+DGDEMTRIIW+ IKD+LI P+LD+D+KY+DLG+ +RDAT D Sbjct: 22 TSATLA-DKIKVKNPIVELDGDEMTRIIWQKIKDQLILPYLDVDLKYYDLGIESRDATDD 80 Query: 342 KVTIESAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIIC 521 ++TI++A A +Y V +KCAT+TPDE RVKEF+LK MW SPNGTIRNIL GTVFRE II Sbjct: 81 QITIDAANAIKEYGVGVKCATITPDEARVKEFHLKKMWLSPNGTIRNILGGTVFRESIII 140 Query: 522 KNVPRLVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFS 692 +PRL+PGW KPI IGRHAFGDQY+ATD++I G+L+L F G E Q + V++++ Sbjct: 141 PCIPRLIPGWEKPIVIGRHAFGDQYKATDLVINEPGRLELRFTPASGGEAQTQ-KVYDYT 199 Query: 693 GAGGVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYET 872 G G V L+MYNTDESI FA AS MA K PLY+STKNTILKKYDGRFKDIFQQ YE Sbjct: 200 GPG-VGLAMYNTDESITGFAHASFKMALAKGLPLYMSTKNTILKKYDGRFKDIFQQIYEQ 258 Query: 873 NWRCRFEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTS 1052 ++ FE G+WYEHRLIDDMVA +KS+GG+V A KNYDGDVQSD++AQGFGSLGLMTS Sbjct: 259 DYAAEFEKQGLWYEHRLIDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSLGLMTS 318 Query: 1053 VLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLL 1232 L+ PDG+ EAEAAHGTVTRHYR HQ+G ETSTNSIASIFAW+ GLA R KLD+ ++ Sbjct: 319 ALMTPDGKAYEAEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLAQRGKLDETPDVV 378 Query: 1233 DFTQKLEAACVGTVESGK-MTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELR 1388 DF KLE A + TVE + MTKDLAL + G T R Y+ T EF+DAVA+ L+ Sbjct: 379 DFASKLEQATIDTVEVDRIMTKDLALAM-GKT-DRSAYVTTTEFLDAVADRLK 429
>P50215:IDH_SPHYA Isocitrate dehydrogenase [NADP] - Sphingomonas yanoikuyae| Length = 406 Score = 520 bits (1340), Expect = e-147 Identities = 253/406 (62%), Positives = 312/406 (76%), Gaps = 1/406 (0%) Frame = +3 Query: 186 KIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAE 365 KI+V NP+VE+DGDEMTRIIW+WI+++LI P+LD+D+KY+DL + RD T D++TI++A Sbjct: 3 KIKVKNPVVEIDGDEMTRIIWEWIRERLILPYLDVDLKYYDLSVEKRDETSDQITIDAAN 62 Query: 366 ATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVP 545 A +Y V +KCAT+TPDE RV+EF LK MW+SPNGTIRNIL G VFREPI+ KNVPRLVP Sbjct: 63 AIKEYGVGVKCATITPDEARVEEFGLKKMWKSPNGTIRNILGGVVFREPIVIKNVPRLVP 122 Query: 546 GWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIFDGIE-EQIELDVFNFSGAGGVALSMY 722 GWT PI +GRHAFGDQY+ATD + G G L + + G E++E +VF F AG VA+ MY Sbjct: 123 GWTDPIVVGRHAFGDQYKATDFKVPGAGTLTMKWVGTNGEELEYEVFEFPSAG-VAMGMY 181 Query: 723 NTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAG 902 N DESIR FA+AS N + WP+YLSTKNTILK YDGRFKD+FQ+ ++ + +F+ AG Sbjct: 182 NLDESIRDFAKASFNYGLNRGWPVYLSTKNTILKAYDGRFKDLFQEVFDAEFADKFKAAG 241 Query: 903 IWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTV 1082 I YEHRLIDDMVA ALK G +VWACKNYDGDVQSD +AQGFGSLGLMTSVL+ PDG+TV Sbjct: 242 IVYEHRLIDDMVASALKWSGKFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDGKTV 301 Query: 1083 EAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAAC 1262 EAEAAHGTVTRHYR HQ+G TSTN IASIFAW+ GL+ R K DD ++ F + LE C Sbjct: 302 EAEAAHGTVTRHYRQHQQGKATSTNPIASIFAWTQGLSFRGKFDDTPDVVKFAETLEQVC 361 Query: 1263 VGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRLS 1400 + TVE G MTKDLALLI GP ++ T +F +A+ L ++ Sbjct: 362 IKTVEGGAMTKDLALLI-GPD---QAWMTTEQFFEAIRVNLEAEMA 403
>P41939:IDHC_YEAST Isocitrate dehydrogenase [NADP] cytoplasmic - Saccharomyces| cerevisiae (Baker's yeast) Length = 412 Score = 520 bits (1340), Expect = e-147 Identities = 255/409 (62%), Positives = 318/409 (77%), Gaps = 3/409 (0%) Frame = +3 Query: 186 KIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAE 365 KI+VANPIVEMDGDE TRIIW I+DKL+ P+LD+D+KY+DL + RD T D+VT++SA Sbjct: 3 KIKVANPIVEMDGDEQTRIIWHLIRDKLVLPYLDVDLKYYDLSVEYRDQTNDQVTVDSAT 62 Query: 366 ATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVP 545 ATLKY VA+KCAT+TPDE RV+EF+LK MW+SPNGTIRNIL GTVFREPII +PRLVP Sbjct: 63 ATLKYGVAVKCATITPDEARVEEFHLKKMWKSPNGTIRNILGGTVFREPIIIPRIPRLVP 122 Query: 546 GWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIFDGIE--EQIELDVFNFSGAGGVALSM 719 W KPI IGRHAFGDQY+ATD+I+ G+L+L++ ++L VF++ GGVA+ M Sbjct: 123 QWEKPIIIGRHAFGDQYKATDVIVPEEGELRLVYKSKSGTHDVDLKVFDYPEHGGVAMMM 182 Query: 720 YNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDA 899 YNT +SI FA+AS +A +++ PLY +TKNTILKKYDG+FKD+F+ Y +++ +FE Sbjct: 183 YNTTDSIEGFAKASFELAIERKLPLYSTTKNTILKKYDGKFKDVFEAMYARSYKEKFESL 242 Query: 900 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 1079 GIWYEHRLIDDMVA LKS+GGY+ A KNYDGDV+SD++AQGFGSLGLMTSVL+ PDG+T Sbjct: 243 GIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDGKT 302 Query: 1080 VEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAA 1259 E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+ G+ R KLD+ ++ F Q LE+A Sbjct: 303 FESEAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILESA 362 Query: 1260 CVGTV-ESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRLSA 1403 V TV E G MTKDLAL++ R Y+ T EFIDAV L+ A Sbjct: 363 TVNTVQEDGIMTKDLALIL--GKSERSAYVTTEEFIDAVESRLKKEFEA 409
>O13294:IDH2_CANTR Isocitrate dehydrogenase [NADP] peroxisomal - Candida tropicalis| (Yeast) Length = 411 Score = 519 bits (1337), Expect = e-146 Identities = 261/409 (63%), Positives = 315/409 (77%), Gaps = 4/409 (0%) Frame = +3 Query: 183 EKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESA 362 +KI V NPIVEMDGDEMTRIIW++IKDKLI P+L++D+KY+DLG+ RD T DKVT ++A Sbjct: 5 QKITVKNPIVEMDGDEMTRIIWQFIKDKLILPYLNVDLKYYDLGIEYRDKTDDKVTTDAA 64 Query: 363 EATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLV 542 EA L+Y V +KCAT+TPDE RVKEFNLK MW SPNGT+RN++ GTVFREPI+ N+PR+V Sbjct: 65 EAILQYGVGVKCATITPDEARVKEFNLKKMWLSPNGTLRNVIGGTVFREPIVIDNIPRIV 124 Query: 543 PGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF---DGIEEQIELDVFNFSGAGGVAL 713 P W KPI IGRHAFGDQY+ATD++I G LKL+F DG E Q E V+ F G G VAL Sbjct: 125 PSWEKPIIIGRHAFGDQYKATDVVIPAAGDLKLVFKPKDGGEVQ-EFPVYQFDGPG-VAL 182 Query: 714 SMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFE 893 SMYNTD SI FAE+S +A +++ L+ STKNTILKKYDG+FKDIF+ Y + ++ + + Sbjct: 183 SMYNTDASITDFAESSFQLAIERKLNLFSSTKNTILKKYDGKFKDIFEGLYASKYKTKMD 242 Query: 894 DAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDG 1073 + GIWYEHRLIDDMVA LKS+GGY+ A KNYDGDVQSD++AQGFGSLGLMTSVLV PDG Sbjct: 243 ELGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDG 302 Query: 1074 RTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLE 1253 + E+EAAHGTVTRHYR HQ+G ETSTNSIASI+AW+ GL R KLDD ++ F ++LE Sbjct: 303 KAFESEAAHGTVTRHYRQHQQGKETSTNSIASIYAWTRGLIQRGKLDDTPEVVKFAEELE 362 Query: 1254 AACVGTVESGK-MTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRL 1397 A + TV MTKDLA L G T R Y+ T EFID VA L L Sbjct: 363 KAVIETVSKDNIMTKDLA-LTQGKT-DRSSYVTTEEFIDGVANRLNKNL 409
>P65097:IDH_MYCTU Isocitrate dehydrogenase [NADP] - Mycobacterium tuberculosis| Length = 409 Score = 516 bits (1328), Expect = e-145 Identities = 255/407 (62%), Positives = 309/407 (75%), Gaps = 2/407 (0%) Frame = +3 Query: 186 KIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAE 365 KI+V+ P+VE+DGDEMTR+IWK IKD LI P+LD+ + Y+DLG+ +RDAT D+VTI++A Sbjct: 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 Query: 366 ATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVP 545 A K+ V +KCAT+TPDE RV+EFNLK MW SPNGTIRNIL GT+FREPI+ NVPRLVP Sbjct: 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 Query: 546 GWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIFDGIEEQIEL--DVFNFSGAGGVALSM 719 GWTKPI IGRHAFGDQYRAT+ + G + L F + + ++ + GGV L M Sbjct: 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 Query: 720 YNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDA 899 YN ESIR FA AS + +WP+YLSTKNTILK YDG FKD F++ YE ++ +FE A Sbjct: 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 Query: 900 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 1079 G+ YEHRLIDDMVA LK EGGYVWACKNYDGDVQSD +AQG+GSLGLMTSVL+ DG+T Sbjct: 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 Query: 1080 VEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAA 1259 VEAEAAHGTVTRHYR +Q G TSTN IASIFAW+ GL HR KLD ++DF KLE+ Sbjct: 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 Query: 1260 CVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRLS 1400 + TVESGKMTKDLA+LI GP +LN+ EF+DA+A+ L L+ Sbjct: 366 VIATVESGKMTKDLAILI-GP---EQDWLNSEEFLDAIADNLEKELA 408
>P65098:IDH_MYCBO Isocitrate dehydrogenase [NADP] - Mycobacterium bovis| Length = 409 Score = 516 bits (1328), Expect = e-145 Identities = 255/407 (62%), Positives = 309/407 (75%), Gaps = 2/407 (0%) Frame = +3 Query: 186 KIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAE 365 KI+V+ P+VE+DGDEMTR+IWK IKD LI P+LD+ + Y+DLG+ +RDAT D+VTI++A Sbjct: 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 Query: 366 ATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVP 545 A K+ V +KCAT+TPDE RV+EFNLK MW SPNGTIRNIL GT+FREPI+ NVPRLVP Sbjct: 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 Query: 546 GWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIFDGIEEQIEL--DVFNFSGAGGVALSM 719 GWTKPI IGRHAFGDQYRAT+ + G + L F + + ++ + GGV L M Sbjct: 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 Query: 720 YNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDA 899 YN ESIR FA AS + +WP+YLSTKNTILK YDG FKD F++ YE ++ +FE A Sbjct: 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 Query: 900 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 1079 G+ YEHRLIDDMVA LK EGGYVWACKNYDGDVQSD +AQG+GSLGLMTSVL+ DG+T Sbjct: 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 Query: 1080 VEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAA 1259 VEAEAAHGTVTRHYR +Q G TSTN IASIFAW+ GL HR KLD ++DF KLE+ Sbjct: 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 Query: 1260 CVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRLS 1400 + TVESGKMTKDLA+LI GP +LN+ EF+DA+A+ L L+ Sbjct: 366 VIATVESGKMTKDLAILI-GP---EQDWLNSEEFLDAIADNLEKELA 408
>P79089:IDHP_ASPNG Isocitrate dehydrogenase [NADP], mitochondrial precursor -| Aspergillus niger Length = 498 Score = 514 bits (1325), Expect = e-145 Identities = 257/409 (62%), Positives = 313/409 (76%), Gaps = 2/409 (0%) Frame = +3 Query: 186 KIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAE 365 KI+V NP+VE+DGDEMTRIIW+ I++KLI P+LD+D+KY+DLGL RD T D+VT+E+AE Sbjct: 92 KIKVKNPVVELDGDEMTRIIWQEIREKLILPYLDVDLKYYDLGLEYRDQTDDQVTVEAAE 151 Query: 366 ATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVP 545 A KY V +KCAT+TPDE RV+EF LK MW SPNGTIRNIL GTVFREPII +PRLVP Sbjct: 152 AIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIIIPAIPRLVP 211 Query: 546 GWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIFDGIEEQIE-LDVFNFSGAGGVALSMY 722 GW KPI IGRHAFGDQYRATD +I G GKL+L++ + + E + V++F G GG+A + Y Sbjct: 212 GWNKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPVNGEPETVKVYDFQG-GGIAQTQY 270 Query: 723 NTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAG 902 NTDESIR FA AS MA K PLY+STKNTILK+YDGRFKDIFQ+ YE+ ++ FE Sbjct: 271 NTDESIRGFAHASFQMALLKGLPLYMSTKNTILKRYDGRFKDIFQEIYESTYQKDFEAKN 330 Query: 903 IWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTV 1082 +WYEHRLIDDMVA +KSEGG+V A KNYDGDVQSD++AQGFGSLGLMTS LV P G Sbjct: 331 LWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSTLVTPTGEAF 390 Query: 1083 EAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAAC 1262 E+EAAHGTVTRHYR HQKG ETSTN IASIFAW+ GL R KLD+ ++ F ++LE AC Sbjct: 391 ESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEELERAC 450 Query: 1263 VGTV-ESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRLSAK 1406 + V + G MTKDLAL R+ ++ T E++ AV L+ L ++ Sbjct: 451 IEVVNDEGIMTKDLALAC--GRKEREAWVTTREYMAAVERRLKANLKSR 497
>P21954:IDHP_YEAST Isocitrate dehydrogenase [NADP], mitochondrial precursor -| Saccharomyces cerevisiae (Baker's yeast) Length = 428 Score = 506 bits (1304), Expect = e-142 Identities = 256/419 (61%), Positives = 315/419 (75%), Gaps = 5/419 (1%) Frame = +3 Query: 162 TAAPMAFEKIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGD 341 T+ AF KI+V P+VE+DGDEMTRIIW IK KLI P+LD+D+KY+DL + +RDAT D Sbjct: 11 TSRLAAFSKIKVKQPVVELDGDEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSD 70 Query: 342 KVTIESAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIIC 521 K+T ++AEA KY V IKCAT+TPDE RVKEFNL MW+SPNGTIRNIL GTVFREPI+ Sbjct: 71 KITQDAAEAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTVFREPIVI 130 Query: 522 KNVPRLVPGWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIFDGIE----EQIELDVFNF 689 +PRLVP W KPI IGRHA GDQY+ATD +I G G L+L++ + + L V+++ Sbjct: 131 PRIPRLVPRWEKPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYDY 190 Query: 690 SGAGGVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYE 869 G+G VA++MYNTDESI FA +S +A K+ L+LSTKNTILKKYDGRFKDIFQ+ YE Sbjct: 191 KGSG-VAMAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYE 249 Query: 870 TNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMT 1049 ++ +FE GI YEHRLIDDMVA +KS+GG++ A KNYDGDVQSD++AQGFGSLGLMT Sbjct: 250 AQYKSKFEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMT 309 Query: 1050 SVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRL 1229 S+LV PDG+T E+EAAHGTVTRHYR +QKG ETSTNSIASIFAWS GL R +LD+ L Sbjct: 310 SILVTPDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPAL 369 Query: 1230 LDFTQKLEAACVGTV-ESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRLSA 1403 F LE+A + TV + G MTKDLAL R Y+ T EF+DAV + L+ + + Sbjct: 370 CKFANILESATLNTVQQDGIMTKDLALACGNN--ERSAYVTTEEFLDAVEKRLQKEIKS 426
>P53982:IDHH_YEAST Isocitrate dehydrogenase [NADP] - Saccharomyces cerevisiae (Baker's| yeast) Length = 420 Score = 504 bits (1298), Expect = e-142 Identities = 249/412 (60%), Positives = 321/412 (77%), Gaps = 3/412 (0%) Frame = +3 Query: 186 KIQVANPIVEMDGDEMTRIIWKWIKDKLIFPFLDLDIKYFDLGLPNRDATGDKVTIESAE 365 KI+V +PIVEMDGDE TR+IWK IK+KLI P+LD+D+KY+DL + RD T D+VT +S+ Sbjct: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62 Query: 366 ATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVP 545 ATLKY VA+KCAT+TPDE R+KEFNLK MW+SPNGTIRNIL GTVFREPII +PRLVP Sbjct: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122 Query: 546 GWTKPICIGRHAFGDQYRATDIIIRGTGKLKLIF--DGIEEQIELDVFNFSGAGGVALSM 719 W KPI IGRHAFGDQYRATDI I+ GKL+L F D +E I+L V+ F +GG+A++M Sbjct: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182 Query: 720 YNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDA 899 +NT++SI+ FA+AS +A +++ PL+ +TKNTILK YD +FK IF ++ ++ +F+ Sbjct: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242 Query: 900 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 1079 I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD++AQGFGSLGLMTS+L+ PDG+T Sbjct: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302 Query: 1080 VEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAA 1259 E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+ + R KLD+ ++ F LE A Sbjct: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362 Query: 1260 CVGTVE-SGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRLSAKSK 1412 + TV+ GKMTKDLAL++ G T +R Y+ T EFID VA+ L+ + + ++ Sbjct: 363 TLDTVQVGGKMTKDLALML-GKT-NRSSYVTTEEFIDEVAKRLQNMMLSSNE 412
>P16273:PRPX_HORVU Pathogen-related protein - Hordeum vulgare (Barley)| Length = 235 Score = 67.4 bits (163), Expect = 2e-10 Identities = 34/41 (82%), Positives = 37/41 (90%), Gaps = 1/41 (2%) Frame = -1 Query: 1975 VDEEMKVEKA*YFYERGNFLASFLSAPVA-ASASGCPVMRG 1856 VDE+ KVEKA +FYERGNFLASFL+AP A ASASGCPVMRG Sbjct: 193 VDEDTKVEKAEFFYERGNFLASFLTAPAASASASGCPVMRG 233
>O29610:IDH_ARCFU Isocitrate dehydrogenase [NADP] - Archaeoglobus fulgidus| Length = 412 Score = 45.8 bits (107), Expect = 7e-04 Identities = 92/370 (24%), Positives = 145/370 (39%), Gaps = 18/370 (4%) Frame = +3 Query: 336 GDKVTIESAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPI 515 G+ + ++ A ++ VA+K TP G +RS N TIR +L+ P+ Sbjct: 77 GNYLPDDTLNAIKEFRVALKGPLTTPVGGG---------YRSLNVTIRQVLDLYANVRPV 127 Query: 516 I-CKNVPRLVPGWTKP-ICIGRHAFGDQYRATDIIIRGTGKLKLIFDGIEEQIELDVFNF 689 K VP + K I R D Y + LKLI ++ + + + Sbjct: 128 YYLKGVPSPIKHPEKVNFVIFRENTEDVYAGIEWPRGSEEALKLI-RFLKNEFGVTIRED 186 Query: 690 SGAGGVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQ--N 863 SG G +S + T +R ++ R + L K I+K +G F+D + Sbjct: 187 SGIGIKPISEFATKRLVRMAIRYAIE---NNRKSVTLVHKGNIMKYTEGAFRDWGYEVAK 243 Query: 864 YETNWRCRFEDAGIWYEH-------------RLIDDMVAYALKSEGGY-VWACKNYDGDV 1001 E C ED +W ++ R+ D+M L Y V A N +GD Sbjct: 244 QEFGEYCITEDE-LWDKYGGKQPEGKIVVKDRIADNMFQQILTRTDEYDVIALPNLNGDY 302 Query: 1002 QSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAW 1181 SD A G LG+ + DG V E HG+ ++ G+ N A I Sbjct: 303 LSDAAAALIGGLGIAPGSNI-GDGIGV-FEPVHGSAPKY------AGQNKVNPTAEIL-- 352 Query: 1182 STGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEF 1361 TG A + + D ++ ++ A T+ SG +T D+ + G V T EF Sbjct: 353 -TG----ALMFEYIGWKDASEMIKKAVEMTISSGIVTYDIHRHMGGTKV------GTREF 401 Query: 1362 IDAVAEELRT 1391 +AV E L++ Sbjct: 402 AEAVVENLQS 411
>Q8CNX4:IDH_STAES Isocitrate dehydrogenase [NADP] - Staphylococcus epidermidis (strain| ATCC 12228) Length = 422 Score = 45.4 bits (106), Expect = 0.001 Identities = 90/389 (23%), Positives = 152/389 (39%), Gaps = 35/389 (8%) Frame = +3 Query: 327 DATGDKVTIESAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILN-GTVF 503 D TG+ + E+ E +Y +A+K TP G + RS N +R L+ T Sbjct: 68 DETGEWLPQETLETIKEYLIAVKGPLTTPIGGGI---------RSLNVALRQELDLFTCL 118 Query: 504 REPIICKNVPRLVPGWTKP----ICIGRHAFGDQYRATDIIIRGTGKLKLIFDGIEEQIE 671 R K VP V +P + I R D Y + +GT ++K + D ++ ++ Sbjct: 119 RPVRWFKGVPSPV---KRPEDVDMVIFRENTEDIYAGIE-FKQGTSEVKKVIDFLQNEMG 174 Query: 672 LDVFNF---SGAGGVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRF 842 F SG G +S T+ +RA + +++ R + L K I+K +G F Sbjct: 175 ATNIRFPETSGIGIKPVSKEGTERLVRAAIQYALD---NNRKSVTLVHKGNIMKFTEGSF 231 Query: 843 KD-------------IFQ-QNYETNWRCRFEDAGIWYEHR-------LIDDMVA------ 941 K +F Q Y+ + +DA + + +I D +A Sbjct: 232 KQWGYDLAHNEFGDKVFTWQQYDEIVEQKGKDAANEAQSKAEQEGKIIIKDSIADIFLQQ 291 Query: 942 YALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHY 1121 + V A N +GD SD +A G +G+ + + EA HGT ++ Sbjct: 292 ILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKY- 350 Query: 1122 RVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDL 1301 G N + I + L H + ++ T +EA T+ S +T D Sbjct: 351 -----AGLNKVNPSSEILSSVLMLEHLGWQEAADKI---TDSIEA----TIASKIVTYDF 398 Query: 1302 ALLIHGPTVSRDKYLNTMEFIDAVAEELR 1388 A L+ G K ++T +F D + + +R Sbjct: 399 ARLMDGA-----KEVSTSDFADELIKNIR 422
>Q5HNL1:IDH_STAEQ Isocitrate dehydrogenase [NADP] - Staphylococcus epidermidis (strain| ATCC 35984 / RP62A) Length = 422 Score = 45.4 bits (106), Expect = 0.001 Identities = 90/389 (23%), Positives = 152/389 (39%), Gaps = 35/389 (8%) Frame = +3 Query: 327 DATGDKVTIESAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILN-GTVF 503 D TG+ + E+ E +Y +A+K TP G + RS N +R L+ T Sbjct: 68 DETGEWLPQETLETIKEYLIAVKGPLTTPIGGGI---------RSLNVALRQELDLFTCL 118 Query: 504 REPIICKNVPRLVPGWTKP----ICIGRHAFGDQYRATDIIIRGTGKLKLIFDGIEEQIE 671 R K VP V +P + I R D Y + +GT ++K + D ++ ++ Sbjct: 119 RPVRWFKGVPSPV---KRPEDVDMVIFRENTEDIYAGIE-FKQGTSEVKKVIDFLQNEMG 174 Query: 672 LDVFNF---SGAGGVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRF 842 F SG G +S T+ +RA + +++ R + L K I+K +G F Sbjct: 175 ATNIRFPETSGIGIKPVSKEGTERLVRAAIQYALD---NNRKSVTLVHKGNIMKFTEGSF 231 Query: 843 KD-------------IFQ-QNYETNWRCRFEDAGIWYEHR-------LIDDMVA------ 941 K +F Q Y+ + +DA + + +I D +A Sbjct: 232 KQWGYDLAHNEFGDKVFTWQQYDEIVEQKGKDAANEAQSKAEQEGKIIIKDSIADIFLQQ 291 Query: 942 YALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHY 1121 + V A N +GD SD +A G +G+ + + EA HGT ++ Sbjct: 292 ILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKY- 350 Query: 1122 RVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDL 1301 G N + I + L H + ++ T +EA T+ S +T D Sbjct: 351 -----AGLNKVNPSSEILSSVLMLEHLGWQEAADKI---TDSIEA----TIASKIVTYDF 398 Query: 1302 ALLIHGPTVSRDKYLNTMEFIDAVAEELR 1388 A L+ G K ++T +F D + + +R Sbjct: 399 ARLMDGA-----KEVSTSDFADELIKNIR 422
>P40495:LYS12_YEAST Homoisocitrate dehydrogenase, mitochondrial precursor - Saccharomyces| cerevisiae (Baker's yeast) Length = 371 Score = 44.3 bits (103), Expect = 0.002 Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 1/106 (0%) Frame = +3 Query: 792 LYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY- 968 L ++ K+ +L + DG F++I ++ YE+N + + I Y +++D MV + + Sbjct: 201 LTVTHKSNVLSQSDGLFREICKEVYESN---KDKYGQIKYNEQIVDSMVYRLFREPQCFD 257 Query: 969 VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGT 1106 V N GD+ SD A GSLG++ S V P+ V E HG+ Sbjct: 258 VIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGS 301
>Q9D6R2:IDH3A_MOUSE Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor| - Mus musculus (Mouse) Length = 366 Score = 43.9 bits (102), Expect = 0.003 Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 3/195 (1%) Frame = +3 Query: 726 TDESIRAFAEASMNMAYQK-RWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAG 902 T+E+ + AE + A R + K I++ DG F Q+ E C+ Sbjct: 172 TEEASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLF---LQKCREVAENCK----D 224 Query: 903 IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 1079 I + +D + ++ + V N GD+ SDL A G LG+ S + +G Sbjct: 225 IKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVA 284 Query: 1080 VEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAA 1259 + E+ HGT G+ N A + + L H L D K+EAA Sbjct: 285 I-FESVHGTAP------DIAGKDMANPTALLLSAVMMLRHMG-------LFDHAAKIEAA 330 Query: 1260 CVGTVESGK-MTKDL 1301 C T++ GK +TKDL Sbjct: 331 CFATIKDGKSLTKDL 345
>Q4FP17:LEU3_PELUB 3-isopropylmalate dehydrogenase - Pelagibacter ubique| Length = 368 Score = 43.1 bits (100), Expect = 0.005 Identities = 48/201 (23%), Positives = 84/201 (41%), Gaps = 1/201 (0%) Frame = +3 Query: 702 GVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWR 881 G+ Y T E +R A+ + ++A +KR S + + + + +K+ Q+ ++ ++ Sbjct: 162 GINTHSYTTSEIVRV-AKVAFDLA-RKRSNRVTSCEKSNVMEAGQLWKEEVQELHDKEYK 219 Query: 882 CRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVL 1058 + H L D+ LK+ + V N GD+ SD + GSLGL+ S Sbjct: 220 ------DVELSHMLADNCAMQLLKNPKQFDVIVTDNLFGDMLSDQASMLTGSLGLLPSAS 273 Query: 1059 VCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDF 1238 + + E A + + H G+ N IASI +++ L + LD Sbjct: 274 LGAKNKDGEMRAMYEPI--HGSAPDIAGKEIANPIASILSFAMALRYSLDLDSE------ 325 Query: 1239 TQKLEAACVGTVESGKMTKDL 1301 LE A + G TKD+ Sbjct: 326 ADALEKAVQDVLNDGLRTKDI 346
>P08200:IDH_ECOLI Isocitrate dehydrogenase [NADP] - Escherichia coli| Length = 416 Score = 42.7 bits (99), Expect = 0.006 Identities = 79/366 (21%), Positives = 127/366 (34%), Gaps = 22/366 (6%) Frame = +3 Query: 354 ESAEATLKYNVAIKCATVTPDEGRVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVP 533 E+ + +Y VAIK TP G ++ N+ +R L + IC Sbjct: 87 ETLDLIREYRVAIKGPLTTPVGGGIRSLNV---------ALRQEL------DLYICLRPV 131 Query: 534 RLVPGWTKPI--------CIGRHAFGDQYRATDIIIRGTGKLKLIFDGIEEQIELDVFNF 689 R G P+ I R D Y + K+I + E++ + F Sbjct: 132 RYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVI-KFLREEMGVKKIRF 190 Query: 690 SGAGGVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYE 869 G+ + + + + R A R + L K I+K +G FKD Q Sbjct: 191 PEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAR 250 Query: 870 TNWRCRFEDAGIWYEHR--------LIDDMVAYA------LKSEGGYVWACKNYDGDVQS 1007 + D G W + + +I D++A A L+ V AC N +GD S Sbjct: 251 EEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYIS 310 Query: 1008 DLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWST 1187 D +A G +G+ + EA HGT ++ G+ N + I + Sbjct: 311 DALAAQVGGIGIAPGANI--GDECALFEATHGTAPKY------AGQDKVNPGSIILSAEM 362 Query: 1188 GLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFID 1367 L H + + G + + +T D L+ G K L EF D Sbjct: 363 MLRHMG-------WTEAADLIVKGMEGAINAKTVTYDFERLMDGA-----KLLKCSEFGD 410 Query: 1368 AVAEEL 1385 A+ E + Sbjct: 411 AIIENM 416
>Q99NA5:IDH3A_RAT Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor| - Rattus norvegicus (Rat) Length = 366 Score = 42.7 bits (99), Expect = 0.006 Identities = 46/167 (27%), Positives = 69/167 (41%), Gaps = 2/167 (1%) Frame = +3 Query: 807 KNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACK 983 K I++ DG F Q+ E C+ I + +D + ++ + V Sbjct: 200 KANIMRMSDGLF---LQKCREVAENCK----DIKFNEMYLDTVCLNMVQDPSQFDVLVMP 252 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSI 1163 N GD+ SDL A G LG+ S + +G + E+ HGT G+ N Sbjct: 253 NLYGDILSDLCAGLIGGLGVTQSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305 Query: 1164 ASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGK-MTKDL 1301 A + + L H L D K+EAAC T++ GK +TKDL Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDL 345
>Q9UXB2:LEU3_SULSO 3-isopropylmalate dehydrogenase - Sulfolobus solfataricus| Length = 336 Score = 42.0 bits (97), Expect = 0.010 Identities = 48/210 (22%), Positives = 88/210 (41%), Gaps = 3/210 (1%) Frame = +3 Query: 681 FNFSGAGGVALSMYNTDE-SIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQ 857 F F + GV +++ T E + + ++N A +R + K +++ DG F + + Sbjct: 127 FEFVTSTGVTIAIKVTTEFASKRIVNVALNYALMRRRKVTCVHKANVMRVTDGLFASVCR 186 Query: 858 QNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGS 1034 + + + +E +D A ++ + V N GD+ SD +Q GS Sbjct: 187 EILKGK---------VNFEEMYVDAAAANLVRDPTRFDVIVTSNVYGDILSDEASQIAGS 237 Query: 1035 LGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLD 1214 LGL S + R E HG G+ N A + + S L+ +L Sbjct: 238 LGLAPSANI--GDRKSMFEPVHGA------AFDIAGKGIANPTAFLLSVSMMLSRMYELS 289 Query: 1215 DNKRLLDFTQKLEAACVGTVESG-KMTKDL 1301 + + ++ LE A + T +SG K+T+D+ Sbjct: 290 KENKYILASKSLENAIIETYKSGNKLTEDV 319
>Q1MA50:LEU3_RHIL3 3-isopropylmalate dehydrogenase - Rhizobium leguminosarum bv. viciae| (strain 3841) Length = 370 Score = 42.0 bits (97), Expect = 0.010 Identities = 55/232 (23%), Positives = 96/232 (41%), Gaps = 2/232 (0%) Frame = +3 Query: 702 GVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWR 881 G+ +Y+T E I A + MA ++ + K ++K ++ Q + Sbjct: 159 GIDTQVYDTYE-IERIAGVAFEMARTRQNRVCSMEKRNVMKS-----GVLWNQVVTETHK 212 Query: 882 CRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSV- 1055 ++ D + EH L D ++ + V N GD+ SD+ A GSLG++ S Sbjct: 213 AKYSDVQL--EHMLADAGGMQLVRQPKQFDVIVTDNLFGDMLSDVAAMLTGSLGMLPSAS 270 Query: 1056 LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLD 1235 L PDG+T + +A + V H G+ N IA I +++ L + + L+ Sbjct: 271 LGAPDGKTGKRKALYEPV--HGSAPDIAGKGIANPIAMIASFAMCLRY------SFNLVK 322 Query: 1236 FTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRT 1391 LE A ++ G T D+ + + T+E DA+ E +T Sbjct: 323 EADDLEKAIANVLDKGIRTGDI-------MADGARQVGTVEMGDAILAEFKT 367
>P24404:LEU3_AGRT5 3-isopropylmalate dehydrogenase - Agrobacterium tumefaciens (strain| C58 / ATCC 33970) Length = 370 Score = 41.6 bits (96), Expect = 0.014 Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 2/202 (0%) Frame = +3 Query: 702 GVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWR 881 G+ +Y+T E I A + +A + + K ++K ++ Q Sbjct: 159 GIDTQIYDTFE-IERIASVAFELARSRDNRVCSMEKRNVMKS-----GVLWNQVVTETHA 212 Query: 882 CRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSV- 1055 +++D + EH L D ++ + V N GD+ SD+ A GSLG++ S Sbjct: 213 AKYKDVQL--EHMLADAGGMQLVRKPKQFDVIVTDNLFGDMLSDVAAMLTGSLGMLPSAS 270 Query: 1056 LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLD 1235 L PD +T + +A + V H G++ N IA I +++ L + + ++D Sbjct: 271 LGAPDAKTGKRKAMYEPV--HGSAPDIAGKSIANPIAMIASFAMCLRY------SFNMVD 322 Query: 1236 FTQKLEAACVGTVESGKMTKDL 1301 KLEAA ++ G T D+ Sbjct: 323 EATKLEAAIANVLDKGIRTADI 344
>Q945K7:IDH5_ARATH Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial| precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 374 Score = 41.6 bits (96), Expect = 0.014 Identities = 74/296 (25%), Positives = 118/296 (39%), Gaps = 3/296 (1%) Frame = +3 Query: 423 RVKEFNLKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVPGWTKPICIGRHAFGDQYRA 602 R + LK +P G LN T+ +E + NV +P C + +Y Sbjct: 101 RRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANV--------RP-CYSLPGYKTRYDD 151 Query: 603 TDII-IRGTGKLKLIFDGIEEQIELDVFNFSGAGGVALSMYNTDESIRAFAEASMNMAYQ 779 D+I IR + + + G+E Q+ V +L + S+R A + Sbjct: 152 VDLITIRENTEGE--YSGLEHQVVRGVVE-------SLKIITRQASLRVAEYAFLYAKTH 202 Query: 780 KRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSE 959 R + K I++K DG F ++ E + I YE +ID+ +K+ Sbjct: 203 GRERVSAIHKANIMQKTDGLFLKCCREVAE-------KYPEITYEEVVIDNCCMMLVKNP 255 Query: 960 GGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQK 1136 + V N GD+ SDL A G LGL S + DG + AEA HG+ Sbjct: 256 ALFDVLVMPNLYGDIISDLCAGLVGGLGLTPSCNIGEDGVAL-AEAVHGSAP------DI 308 Query: 1137 GGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGK-MTKDL 1301 G+ N A + + L H L N++ +++ +A + T+ GK T DL Sbjct: 309 AGKNLANPTALLLSGVMMLRH---LKFNEQ----AEQIHSAIINTIAEGKYRTADL 357
>Q5R678:IDH3A_PONPY Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor| - Pongo pygmaeus (Orangutan) Length = 366 Score = 41.6 bits (96), Expect = 0.014 Identities = 45/167 (26%), Positives = 69/167 (41%), Gaps = 2/167 (1%) Frame = +3 Query: 807 KNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACK 983 K I++ DG F Q+ E C+ I + +D + ++ + V Sbjct: 200 KANIMRMSDGLF---LQKCREVAENCK----DIKFNEMYLDTVCLNMVQDPSQFDVLVMP 252 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSI 1163 N GD+ SDL A G LG+ S + +G + E+ HGT G+ N Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305 Query: 1164 ASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGK-MTKDL 1301 A + + L H L D ++EAAC T++ GK +TKDL Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAARIEAACFATIKDGKSLTKDL 345
>Q28480:IDH3A_MACFA Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor| - Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) Length = 347 Score = 41.6 bits (96), Expect = 0.014 Identities = 45/167 (26%), Positives = 69/167 (41%), Gaps = 2/167 (1%) Frame = +3 Query: 807 KNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACK 983 K I++ DG F Q+ E C+ I + +D + ++ + V Sbjct: 181 KANIMRMSDGLF---LQKCREVAENCK----DIKFNEMYLDTVCLNMVQDPSQFDVLVMP 233 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSI 1163 N GD+ SDL A G LG+ S + +G + E+ HGT G+ N Sbjct: 234 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 286 Query: 1164 ASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGK-MTKDL 1301 A + + L H L D ++EAAC T++ GK +TKDL Sbjct: 287 ALLLSAVMMLRHMG-------LFDHAARIEAACFATIKDGKSLTKDL 326
>Q9PLW0:LEU3_CAMJE 3-isopropylmalate dehydrogenase - Campylobacter jejuni| Length = 358 Score = 41.2 bits (95), Expect = 0.018 Identities = 54/223 (24%), Positives = 86/223 (38%), Gaps = 2/223 (0%) Frame = +3 Query: 726 TDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGI 905 T + I A + A ++ ++L K +L I + N ++D + Sbjct: 162 TKKEIERIARIAFESARIRKKKVHLIDKANVLAS------SILWREVVANVAKDYQDINL 215 Query: 906 WYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDG-RT 1079 E+ +D+ +K+ + V C N GD+ SD +A GSLGL++S + G Sbjct: 216 --EYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGL 273 Query: 1080 VEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAA 1259 E H + N IA I + + L + K + Q +E A Sbjct: 274 YEPAGGSAPDIAHLNI--------ANPIAQILSAALMLKYSFKEE------QAAQDIENA 319 Query: 1260 CVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELR 1388 + GKMTKDL + YLNT E D + E L+ Sbjct: 320 ISLALAQGKMTKDL---------NAKSYLNTDEMGDCILEILK 353
>Q8LG77:IDH6_ARATH Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial| precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 374 Score = 41.2 bits (95), Expect = 0.018 Identities = 76/294 (25%), Positives = 117/294 (39%), Gaps = 7/294 (2%) Frame = +3 Query: 441 LKAMWRSPNGTIRNILNGTVFREPIICKNVPRLVPGWTKPICIGRHAFGDQYRATDII-I 617 LK +P G LN T+ +E + NV +P C + +Y D+I I Sbjct: 107 LKGPMATPIGKGHRSLNLTLRKELNLYANV--------RP-CYSLPGYKTRYDDVDLITI 157 Query: 618 RGTGKLKLIFDGIEEQIELDVFNFSGAGGVALSMYNTDESIRAFAEASMNMAYQKRWPLY 797 R + + + G+E Q+ V +L + S+R A + R + Sbjct: 158 RENTEGE--YSGLEHQVVKGVVE-------SLKIITRKASMRVAEYAFLYAKTHGRKKVS 208 Query: 798 LSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAG----IWYEHRLIDDMVAYALKSEGG 965 K I++K DG F +C E A I+YE +ID+ +K+ Sbjct: 209 AIHKANIMQKTDGLFL-----------QCCDEVAAKYPEIYYEKVVIDNCCMMLVKNPAL 257 Query: 966 Y-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGG 1142 + V N GD+ SDL A G LGL S+ + DG + AEA HG+ G Sbjct: 258 FDVLVMPNLYGDIISDLCAGLVGGLGLTPSMNIGEDGIAL-AEAVHGSAP------DIAG 310 Query: 1143 ETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGK-MTKDL 1301 N A + + L H L NK+ +++ +A + T+ GK T DL Sbjct: 311 MNLANPTALLLSGVMMLRH---LKLNKQ----AEQIHSAIINTIAEGKYRTADL 357
>P50213:IDH3A_HUMAN Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor| - Homo sapiens (Human) Length = 366 Score = 41.2 bits (95), Expect = 0.018 Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 1/107 (0%) Frame = +3 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSI 1163 N GD+ SDL A G LG+ S + +G + E+ HGT G+ N Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305 Query: 1164 ASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGK-MTKDL 1301 A + + L H L D ++EAAC T++ GK +TKDL Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAARIEAACFATIKDGKSLTKDL 345
>P41563:IDH3A_BOVIN Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor| - Bos taurus (Bovine) Length = 366 Score = 41.2 bits (95), Expect = 0.018 Identities = 45/167 (26%), Positives = 68/167 (40%), Gaps = 2/167 (1%) Frame = +3 Query: 807 KNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACK 983 K I++ DG F Q+ E C+ I + +D + ++ + V Sbjct: 200 KANIMRMSDGLF---LQKCREVAENCK----DIKFNEMYLDTVCLNMVQDPSQFDVLVMP 252 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSI 1163 N GD+ SDL A G LG+ S + +G + E+ HGT G+ N Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305 Query: 1164 ASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGK-MTKDL 1301 A + + L H L D K+E AC T++ GK +TKDL Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIETACFATIKDGKSLTKDL 345
>O29627:LEU3_ARCFU 3-isopropylmalate dehydrogenase - Archaeoglobus fulgidus| Length = 326 Score = 40.8 bits (94), Expect = 0.023 Identities = 54/194 (27%), Positives = 73/194 (37%), Gaps = 1/194 (0%) Frame = +3 Query: 807 KNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACK 983 K ++KK G F+D+ ++ + + I Y ID Y + + V Sbjct: 165 KANVMKKTCGLFRDVCREVAK-------DYPEIQYNDYYIDAACMYLVMDPFRFDVIVTT 217 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSI 1163 N GD+ SDL A G LGL S V RT E HG G+ N Sbjct: 218 NMFGDIVSDLAAGLVGGLGLAPSANV--GERTAIFEPVHGA------AFDIAGKGIANPT 269 Query: 1164 ASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKY 1343 A I L H +++ K K+E A T++ GK T DL Sbjct: 270 AMILTACMMLRHFGYVEEAK-------KVEEAVEKTIKEGKKTPDLG-----------GN 311 Query: 1344 LNTMEFIDAVAEEL 1385 L TMEF + VA L Sbjct: 312 LKTMEFANEVASLL 325
>Q5HS77:LEU3_CAMJR 3-isopropylmalate dehydrogenase - Campylobacter jejuni (strain| RM1221) Length = 358 Score = 40.4 bits (93), Expect = 0.030 Identities = 44/161 (27%), Positives = 65/161 (40%), Gaps = 2/161 (1%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDG-RTVE 1085 E+ +D+ +K+ + V C N GD+ SD +A GSLGL++S + G E Sbjct: 216 EYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYE 275 Query: 1086 AEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACV 1265 H + N IA I + + L + K + Q +E A Sbjct: 276 PAGGSAPDIAHLNI--------ANPIAQILSAALMLKYSFKEE------QAAQDIENAIS 321 Query: 1266 GTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELR 1388 + GKMTKDL + YLNT E D + E L+ Sbjct: 322 LALAQGKMTKDL---------NAKSYLNTDEMGDCILEILK 353
>Q6LV25:LEU3_PHOPR 3-isopropylmalate dehydrogenase - Photobacterium profundum| (Photobacterium sp. (strain SS9)) Length = 362 Score = 40.0 bits (92), Expect = 0.039 Identities = 43/159 (27%), Positives = 67/159 (42%), Gaps = 1/159 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + + + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSMGMLPSASLNQE-KFGMYE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N +A I S L R LD+ K + +E A Sbjct: 282 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLDEEKA----ARAIEQAVSQA 329 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELR 1388 +E+G++T DLA + L+T E D +A +R Sbjct: 330 LEAGELTADLA--------GKGAALSTSEMGDKIAAYIR 360
>Q3SNU3:LEU3_NITWN 3-isopropylmalate dehydrogenase - Nitrobacter winogradskyi (strain| Nb-255 / ATCC 25391) Length = 370 Score = 39.7 bits (91), Expect = 0.051 Identities = 58/229 (25%), Positives = 98/229 (42%), Gaps = 2/229 (0%) Frame = +3 Query: 705 VALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRC 884 V +Y+T E I A + ++A ++R L K ++K + ++ Q ++ ++ Sbjct: 160 VDTQVYDTYE-IERIARVAFDLARKRRNKLTSMEKRNVMKT-GVLWHEVVTQVHQREYK- 216 Query: 885 RFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSV-L 1058 + +H+L D ++ + V N GD+ SD+ A GSLG++ S L Sbjct: 217 -----DVALQHQLADSGGMQLVRWPKQFDVIVTDNLFGDMLSDIAAMLTGSLGMLPSASL 271 Query: 1059 VCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDF 1238 D +T + A + V H G+ N IA + S G+A R D D Sbjct: 272 GDTDPKTEKRRALYEPV--HGSAPDIAGQGLANPIAMLA--SFGMALRYSFDRG----DL 323 Query: 1239 TQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 KL+AA + G T DL G TV ++T + +A+ +EL Sbjct: 324 ADKLDAAIAAVLAKGLRTADLK--SEGATV-----VSTSQMGEAIVKEL 365
>Q8E9N3:LEU3_SHEON 3-isopropylmalate dehydrogenase - Shewanella oneidensis| Length = 364 Score = 39.3 bits (90), Expect = 0.067 Identities = 45/177 (25%), Positives = 74/177 (41%), Gaps = 6/177 (3%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ + + EH ID+ L+ + V C N GD+ SD IA GS+ Sbjct: 203 WRQVVEEVAVDFPDVELEHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDEIAMLTGSM 262 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 GL++S + G + E A G+ G+ N IA I + + L H K + Sbjct: 263 GLLSSASMNSTGFGL-FEPAGGSAP------DIAGKGIANPIAQILSAALMLRHSLKQE- 314 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELR 1388 + +E A + SG +T +L + R K T++ D +A+ ++ Sbjct: 315 -----EAASAIERAVTKALNSGYLTGELL-----SSDQRHKAKTTVQMGDFIADAVK 361
>P59515:LEU3_BUCBP 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp.| Baizongia pistaciae Length = 366 Score = 39.3 bits (90), Expect = 0.067 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 1/162 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H +D+ +K+ + V C N GD+ SD A GS+GL+ S + D E Sbjct: 223 HLYVDNAAMQIIKNPSQFDVLLCSNLFGDILSDECAAITGSIGLLPSASL-NDKNFGLYE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + + + KL D L+D+ A T Sbjct: 282 PAGGSAP------DIKGKNIANPIALILSIGMMMRYSFKLYDVADLIDW------AVNKT 329 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRL 1397 ++ G T+D++ +K++NT D +AE L R+ Sbjct: 330 LKLGYRTQDIS--------ENNKFINTSSMGDIIAEILANRI 363
>Q47WG3:LEU3_COLP3 3-isopropylmalate dehydrogenase - Colwellia psychrerythraea (strain| 34H / ATCC BAA-681) (Vibrio psychroerythus) Length = 362 Score = 38.9 bits (89), Expect = 0.088 Identities = 45/178 (25%), Positives = 72/178 (40%), Gaps = 6/178 (3%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ + Y EH +D+ ++ + V C N GD+ SD+ A GS+ Sbjct: 202 WRQVVEEVAVEYPDVELEHLYVDNAAMQLVRDPNQFDVMLCPNLFGDILSDICAMITGSM 261 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 GL+ S + DG + E A G+ G N IA I S L R L+ Sbjct: 262 GLLPSASLNSDGFGM-YEPAGGSAP------DIAGLGVANPIAQIL--SAALMLRYSLNQ 312 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRT 1391 + +E A +++G +T DL P R +T E D + +++ + Sbjct: 313 GAA----AKAIEDAVSNALDNGVLTADLL-----PANERKNAKSTSEVGDYICKQIES 361
>Q98E57:LEU3_RHILO 3-isopropylmalate dehydrogenase - Rhizobium loti (Mesorhizobium loti)| Length = 367 Score = 38.5 bits (88), Expect = 0.11 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 1/107 (0%) Frame = +3 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSV-LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNS 1160 N GD+ SD+ A GS+G++ S L PD +T + +A + V H G+ N Sbjct: 246 NLFGDMLSDIAAMLTGSIGMLPSASLGAPDVKTKKRKALYEPV--HGSAPDIAGKGIANP 303 Query: 1161 IASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDL 1301 IA I +++ L + + ++D +LE A ++ G TKD+ Sbjct: 304 IAMIASFAMCLRY------SFGMVDEADRLEGAIAAVLDQGLRTKDI 344
>Q9JZI9:LEU3_NEIMB 3-isopropylmalate dehydrogenase - Neisseria meningitidis serogroup B| Length = 356 Score = 38.5 bits (88), Expect = 0.11 Identities = 38/148 (25%), Positives = 66/148 (44%), Gaps = 6/148 (4%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR FE+ G Y H +D+ +++ + V A N GD+ SD + GS+ Sbjct: 201 WREIFEEIGKEYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSI 260 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S + +G+ + E +HG+ G+ N +A+I S + R L+D Sbjct: 261 GMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKANPLATIL--SLAMLLRYSLND 311 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDL 1301 R Q++E A ++ G T D+ Sbjct: 312 EAR----AQQVENAVQKVLQQGLRTSDI 335
>Q2K2V0:LEU3_RHIEC 3-isopropylmalate dehydrogenase - Rhizobium etli (strain CFN 42 /| ATCC 51251) Length = 370 Score = 37.7 bits (86), Expect = 0.20 Identities = 48/202 (23%), Positives = 85/202 (42%), Gaps = 2/202 (0%) Frame = +3 Query: 702 GVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWR 881 G+ +Y+T E I A + MA ++ + K ++K ++ Q + Sbjct: 159 GIDTQVYDTYE-IERIAGVAFEMARTRQNRVCSMEKRNVMKS-----GVLWNQVVTETHK 212 Query: 882 CRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSV- 1055 ++ D + EH L D ++ + V N GD+ SD+ A GSLG++ S Sbjct: 213 AKYSDVQL--EHMLADAGGMQLVRQPKQFDVIVTDNLFGDMLSDVAAMLTGSLGMLPSAS 270 Query: 1056 LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLD 1235 L PDG+T + +A + V H G+ N IA I +++ L + + ++ Sbjct: 271 LGAPDGKTGKRKALYEPV--HGSAPDIAGKGIANPIAMIASFAMCLRY------SFNMVK 322 Query: 1236 FTQKLEAACVGTVESGKMTKDL 1301 LE A ++ G T D+ Sbjct: 323 EADDLEKAIANVLDKGIRTGDI 344
>Q65GI9:LEU3_BACLD 3-isopropylmalate dehydrogenase - Bacillus licheniformis (strain DSM| 13 / ATCC 14580) Length = 370 Score = 37.7 bits (86), Expect = 0.20 Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 1/132 (0%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEA 1088 EH L+D+ + + G + + +N GD+ SD + GSLG++ S + G + Sbjct: 219 EHMLVDNAAMQLIYAPGQFDIIVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHL-Y 277 Query: 1089 EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVG 1268 E HG+ G+ N +A+I + + L L+ Q +E A Sbjct: 278 EPVHGSAP------DIAGQNIANPLAAILSAAMMLRTSFGLEAE------AQAVEHAVDQ 325 Query: 1269 TVESGKMTKDLA 1304 + +GK TKDLA Sbjct: 326 VLRAGKRTKDLA 337
>P33197:IDH_THET8 Isocitrate dehydrogenase [NADP] - Thermus thermophilus (strain HB8 /| ATCC 27634 / DSM 579) Length = 496 Score = 37.7 bits (86), Expect = 0.20 Identities = 45/202 (22%), Positives = 81/202 (40%), Gaps = 1/202 (0%) Frame = +3 Query: 783 RWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEG 962 R ++ +TK+ I+K +G K F+Q + E I H ++D+ +K Sbjct: 183 RKKVHCATKSNIMKLAEGTLKRAFEQVAQ-------EYPDIEAVHIIVDNAAHQLVKRPE 235 Query: 963 GY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKG 1139 + V N +GD+ SDL + G LG S + EA HG+ ++ Sbjct: 236 QFEVIVTTNMNGDILSDLTSGLIGGLGFAPSANI--GNEVAIFEAVHGSAPKY------A 287 Query: 1140 GETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDLALLIHG 1319 G+ N A + + L + + +E A + T+E G+ ++ G Sbjct: 288 GKNVINPTAVLLSAVMMLRYLEEFAT-------ADLIENALLYTLEEGR-------VLTG 333 Query: 1320 PTVSRDKYLNTMEFIDAVAEEL 1385 V D+ T E+ +A+ + L Sbjct: 334 DVVGYDRGAKTTEYTEAIIQNL 355
>Q9JU79:LEU3_NEIMA 3-isopropylmalate dehydrogenase - Neisseria meningitidis serogroup A| Length = 356 Score = 37.4 bits (85), Expect = 0.26 Identities = 37/148 (25%), Positives = 66/148 (44%), Gaps = 6/148 (4%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR FE+ G Y H +D+ +++ + V A N GD+ SD + GS+ Sbjct: 201 WREIFEEIGKEYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSI 260 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S + +G+ + E +HG+ G+ N +A++ S + R L+D Sbjct: 261 GMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKANPLATVL--SLAMLLRYSLND 311 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDL 1301 R Q++E A ++ G T D+ Sbjct: 312 EAR----AQQVENAVQKVLQQGLRTGDI 335
>Q9EVH5:LEU3_BUCUE 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp.| Uroleucon erigeronensis Length = 364 Score = 37.4 bits (85), Expect = 0.26 Identities = 42/158 (26%), Positives = 66/158 (41%), Gaps = 1/158 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ + +K + V C N GD+ SD A GS+G++ S + + E Sbjct: 223 HLYIDNAIMQIIKDPSQFDVILCSNLFGDIVSDECAAITGSIGMLPSASLNEKNFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + S + H L K++ D K++ + V Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSVSMLVRHGMNL---KKIAD---KIDESVVSV 329 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 ++ G T D++ H YL T E D +A L Sbjct: 330 LKQGYRTADISNNSH-------NYLKTSEMGDIIANFL 360
>Q8FVF3:LEU3_BRUSU 3-isopropylmalate dehydrogenase - Brucella suis| Length = 370 Score = 37.4 bits (85), Expect = 0.26 Identities = 51/205 (24%), Positives = 86/205 (41%), Gaps = 5/205 (2%) Frame = +3 Query: 702 GVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWR 881 G+ +Y+T E I A+ + +A +R + K ++K N R Sbjct: 159 GIDTQVYDTYE-IERIADVAFELARTRRNKVTSMEKRNVMKSG-------VLWNQVVTAR 210 Query: 882 CRFEDAGIWYEHRLID----DMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMT 1049 + + A + EH L D +V + + + V N GD+ SD+ A GSLG++ Sbjct: 211 HKEKHADVQLEHMLADAGGMQLVRWPKQFD---VILTDNLFGDLLSDVAAMLTGSLGMLP 267 Query: 1050 SV-LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKR 1226 S L D +T + +A + V H G+ N IA I + + L + + Sbjct: 268 SASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANPIAMIASLAMCLRY------SFG 319 Query: 1227 LLDFTQKLEAACVGTVESGKMTKDL 1301 L+ +LEAA G ++ G T D+ Sbjct: 320 LVAEADRLEAAIAGVLDDGIRTADI 344
>Q8YCX4:LEU3_BRUME 3-isopropylmalate dehydrogenase - Brucella melitensis| Length = 370 Score = 37.4 bits (85), Expect = 0.26 Identities = 51/205 (24%), Positives = 86/205 (41%), Gaps = 5/205 (2%) Frame = +3 Query: 702 GVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWR 881 G+ +Y+T E I A+ + +A +R + K ++K N R Sbjct: 159 GIDTQVYDTYE-IERIADVAFELARTRRNKVTSMEKRNVMKSG-------VLWNQGVTAR 210 Query: 882 CRFEDAGIWYEHRLID----DMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMT 1049 + + A + EH L D +V + + + V N GD+ SD+ A GSLG++ Sbjct: 211 HKEKHADVQLEHMLADAGGMQLVRWPKQFD---VILTDNLFGDLLSDVAAMLTGSLGMLP 267 Query: 1050 SV-LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKR 1226 S L D +T + +A + V H G+ N IA I + + L + + Sbjct: 268 SASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANPIAMIASLAMCLRY------SFG 319 Query: 1227 LLDFTQKLEAACVGTVESGKMTKDL 1301 L+ +LEAA G ++ G T D+ Sbjct: 320 LVAEADRLEAAIAGVLDDGIRTADI 344
>Q579B1:LEU3_BRUAB 3-isopropylmalate dehydrogenase - Brucella abortus| Length = 370 Score = 37.4 bits (85), Expect = 0.26 Identities = 51/205 (24%), Positives = 86/205 (41%), Gaps = 5/205 (2%) Frame = +3 Query: 702 GVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWR 881 G+ +Y+T E I A+ + +A +R + K ++K N R Sbjct: 159 GIDTQVYDTYE-IERIADVAFELARTRRNKVTSMEKRNVMKSG-------VLWNQGVTAR 210 Query: 882 CRFEDAGIWYEHRLID----DMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMT 1049 + + A + EH L D +V + + + V N GD+ SD+ A GSLG++ Sbjct: 211 HKEKHADVQLEHMLADAGGMQLVRWPKQFD---VILTDNLFGDLLSDVAAMLTGSLGMLP 267 Query: 1050 SV-LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKR 1226 S L D +T + +A + V H G+ N IA I + + L + + Sbjct: 268 SASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANPIAMIASLAMCLRY------SFG 319 Query: 1227 LLDFTQKLEAACVGTVESGKMTKDL 1301 L+ +LEAA G ++ G T D+ Sbjct: 320 LVAEADRLEAAIAGVLDDGIRTADI 344
>Q2YL58:LEU3_BRUA2 3-isopropylmalate dehydrogenase - Brucella abortus (strain 2308)| Length = 370 Score = 37.4 bits (85), Expect = 0.26 Identities = 51/205 (24%), Positives = 86/205 (41%), Gaps = 5/205 (2%) Frame = +3 Query: 702 GVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWR 881 G+ +Y+T E I A+ + +A +R + K ++K N R Sbjct: 159 GIDTQVYDTYE-IERIADVAFELARTRRNKVTSMEKRNVMKSG-------VLWNQGVTAR 210 Query: 882 CRFEDAGIWYEHRLID----DMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMT 1049 + + A + EH L D +V + + + V N GD+ SD+ A GSLG++ Sbjct: 211 HKEKHADVQLEHMLADAGGMQLVRWPKQFD---VILTDNLFGDLLSDVAAMLTGSLGMLP 267 Query: 1050 SV-LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKR 1226 S L D +T + +A + V H G+ N IA I + + L + + Sbjct: 268 SASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANPIAMIASLAMCLRY------SFG 319 Query: 1227 LLDFTQKLEAACVGTVESGKMTKDL 1301 L+ +LEAA G ++ G T D+ Sbjct: 320 LVAEADRLEAAIAGVLDDGIRTADI 344
>Q7M886:LEU3_WOLSU 3-isopropylmalate dehydrogenase - Wolinella succinogenes| Length = 358 Score = 37.0 bits (84), Expect = 0.33 Identities = 40/154 (25%), Positives = 65/154 (42%), Gaps = 1/154 (0%) Frame = +3 Query: 846 DIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQ 1022 D+ Q ET R E + H ID+ +++ + V N GD+ SD + Sbjct: 193 DVSQLWRETVTRIAKEYPEVELSHMYIDNAAMQLIRNPKQFDVILTGNLFGDILSDEASM 252 Query: 1023 GFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHR 1202 GS+GL+ S + G+ E HG+ G+ N IA+I + S L H Sbjct: 253 LSGSIGLLPSASI--GGKAALYEPIHGSAP------DIAGQGIANPIATIASASMMLRH- 303 Query: 1203 AKLDDNKRLLDFTQKLEAACVGTVESGKMTKDLA 1304 + ++ ++ A V T++ G TKD+A Sbjct: 304 -----SLGEVEAADAIDKAIVKTLKEGYRTKDIA 332
>Q2NVW4:LEU3_SODGM 3-isopropylmalate dehydrogenase - Sodalis glossinidius (strain| morsitans) Length = 364 Score = 37.0 bits (84), Expect = 0.33 Identities = 37/131 (28%), Positives = 54/131 (41%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 224 HLYIDNATMQLIKDPSQFDVMLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGM-YE 282 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N +A I + S L + LD D +E A Sbjct: 283 PAGGSAP------DIAGKDIANPVAQILSASLLLRYSLGLD------DAADAIELAVNQA 330 Query: 1272 VESGKMTKDLA 1304 +E+G T DLA Sbjct: 331 LEAGHRTADLA 341
>Q21CS1:LEU3_RHOPB 3-isopropylmalate dehydrogenase - Rhodopseudomonas palustris (strain| BisB18) Length = 370 Score = 37.0 bits (84), Expect = 0.33 Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 2/161 (1%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSV-LVCPDGRTVE 1085 EH+L D +K + V N GD+ SD+ A GSLG++ S L D T + Sbjct: 221 EHQLADSGGMNLVKWPKQFDVIVTDNLFGDILSDIAAMLTGSLGMLPSASLGAVDANTGK 280 Query: 1086 AEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACV 1265 ++ + V H G+ N +A + S G+A R LD + + KL+AA Sbjct: 281 RKSMYEPV--HGSAPDIAGKGLANPVAMLA--SFGMALRYSLD----MGELADKLDAAIA 332 Query: 1266 GTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELR 1388 + G T D+ G TV ++T + +A+ +E++ Sbjct: 333 AVLAKGLRTADIK--SEGSTV-----ISTSQMGEAILKEMQ 366
>Q5F8T6:LEU3_NEIG1 3-isopropylmalate dehydrogenase - Neisseria gonorrhoeae (strain ATCC| 700825 / FA 1090) Length = 356 Score = 37.0 bits (84), Expect = 0.33 Identities = 37/148 (25%), Positives = 66/148 (44%), Gaps = 6/148 (4%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR FE+ G Y H +D+ +++ + V A N GD+ SD + GS+ Sbjct: 201 WREIFEEIGKQYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSI 260 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S + +G+ + E +HG+ G+ N +A+I S + R L+D Sbjct: 261 GMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKANPLATIL--SLAMLLRYSLND 311 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDL 1301 R Q++E + ++ G T D+ Sbjct: 312 EAR----AQQVENSVQKVLQQGLRTGDI 335
>Q73G93:TRUA_WOLPM tRNA pseudouridine synthase A - Wolbachia pipientis wMel| Length = 245 Score = 36.6 bits (83), Expect = 0.44 Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 3/112 (2%) Frame = +3 Query: 648 DGIEEQIELDVFNFSGAGGVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKK 827 + I+E+IE +FNFSG TD + A + + + +K + LY +N I Sbjct: 25 NSIQEKIENAIFNFSGEKVTLYCGGRTDAGVHALGQVA-HFDMEKEFELY-RIRNAI--N 80 Query: 828 YDGRFKDIFQQNYET---NWRCRFEDAGIWYEHRLIDDMVAYALKSEGGYVW 974 Y + I N E + RF +YE+R+++ AL E GYVW Sbjct: 81 YHLKSIPIVVLNAEVVDDAFHARFSAKKRYYEYRIVNRYAPAAL--ETGYVW 130
>P37412:LEU3_SALTY 3-isopropylmalate dehydrogenase - Salmonella typhimurium| Length = 363 Score = 36.6 bits (83), Expect = 0.44 Identities = 40/131 (30%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD N D +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRA 329 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 330 LEEGVRTGDLA 340
>Q5PDG2:LEU3_SALPA 3-isopropylmalate dehydrogenase - Salmonella paratyphi-a| Length = 363 Score = 36.6 bits (83), Expect = 0.44 Identities = 40/131 (30%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD N D +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRA 329 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 330 LEEGVRTGDLA 340
>Q57TE7:LEU3_SALCH 3-isopropylmalate dehydrogenase - Salmonella choleraesuis| Length = 363 Score = 36.6 bits (83), Expect = 0.44 Identities = 40/131 (30%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD N D +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRA 329 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 330 LEEGVRTGDLA 340
>P06333:TCB1_RABIT T-cell receptor beta chain ANA 11 - Oryctolagus cuniculus (Rabbit)| Length = 319 Score = 36.2 bits (82), Expect = 0.57 Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 3/89 (3%) Frame = -2 Query: 1065 GTPKPMS*DLTIQNLEQLDRSAHLHHNSCKPKHSHLHSLGHRPPYHQSVYVHT---IFLH 895 G P+ +T ++ +A L+ P H+H HS P H + HT +H Sbjct: 17 GQPRRKWLTMTPEHARPPTTTAMLYDGFLWPSHTHRHSYLLHPHTHVCTHTHTCTHTHIH 76 Query: 894 PQTCISNLFHSFVGICL*TFRHIFSGLCS 808 T + H+F +C+ T H + C+ Sbjct: 77 ASTHVCIHTHTFTHLCIHTLTHALTLTCA 105
>Q32K21:LEU3_SHIDS 3-isopropylmalate dehydrogenase - Shigella dysenteriae serotype 1| (strain Sd197) Length = 363 Score = 36.2 bits (82), Expect = 0.57 Identities = 39/131 (29%), Positives = 54/131 (41%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD + D +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAD----DAASAIERAINRA 329 Query: 1272 VESGKMTKDLA 1304 +E G T+DLA Sbjct: 330 LEEGIRTRDLA 340
>Q2G4X5:LEU3_NOVAD 3-isopropylmalate dehydrogenase - Novosphingobium aromaticivorans| (strain DSM 12444) Length = 352 Score = 36.2 bits (82), Expect = 0.57 Identities = 33/135 (24%), Positives = 58/135 (42%), Gaps = 5/135 (3%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEA 1088 EH +D+ +++ G + V N GD+ SD + GS+GL+ S + E Sbjct: 213 EHMYVDNAAMQLVRAPGNFDVVVTGNLFGDILSDQASMCVGSIGLLASASL------GER 266 Query: 1089 EAAHGTVTRHYRVHQK----GGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEA 1256 E +GT + +H G+ N +A+I + + L H L+ ++EA Sbjct: 267 ETEYGTFGLYEPIHGSAPDIAGKGLANPMATILSAAMLLRHSLGLE------VAADRIEA 320 Query: 1257 ACVGTVESGKMTKDL 1301 A + G + +DL Sbjct: 321 AVAKALADGVLGRDL 335
>P43860:LEU3_HAEIN 3-isopropylmalate dehydrogenase - Haemophilus influenzae| Length = 358 Score = 36.2 bits (82), Expect = 0.57 Identities = 37/132 (28%), Positives = 57/132 (43%), Gaps = 1/132 (0%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEA 1088 EH ID+ +KS + V C N GD+ SD A GS+G++ S + +G + Sbjct: 221 EHIYIDNATMQLIKSPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGL-Y 279 Query: 1089 EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVG 1268 E A G+ G+ N IA I + + L + L+ + +E+A Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAADAIESAVQK 327 Query: 1269 TVESGKMTKDLA 1304 + SG T DLA Sbjct: 328 VLASGHRTADLA 339
>Q9EVI1:LEU3_BUCUO 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp.| Uroleucon obscurum Length = 364 Score = 36.2 bits (82), Expect = 0.57 Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 1/158 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ + +K+ + V C N GD+ SD A GS+G++ S + + + E Sbjct: 224 HLYIDNAIMQIIKNPNQFDVLLCPNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYE 282 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + S + + L D K++ + + Sbjct: 283 PAGGSAP------DIAGKNIANPIAQILSLSMLVRY------GMNLKDIADKIDKSVLSV 330 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 ++ G T D++ + + YL T E D +A L Sbjct: 331 LKKGYRTADIS--------NNNNYLKTNEMGDVIANAL 360
>Q9VWH4:IDH3A_DROME Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial| precursor - Drosophila melanogaster (Fruit fly) Length = 377 Score = 36.2 bits (82), Expect = 0.57 Identities = 51/199 (25%), Positives = 82/199 (41%), Gaps = 7/199 (3%) Frame = +3 Query: 726 TDESIRAFAEASMNMAYQK-RWPLYLSTKNTILKKYDGRF----KDIFQQNYETNWRCRF 890 T+E+ + AE + A R + + K I++ DG F +D+ Q+ E Sbjct: 188 TEEASKRVAEYAFQYAKNNNRKKVTVVHKANIMRMSDGLFLRCVRDMAQKFPE------- 240 Query: 891 EDAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCP 1067 I +E + +D + +++ G Y V N GD+ SD+ A G LGL S + Sbjct: 241 ----IQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLVGGLGLTPSGNMGL 296 Query: 1068 DGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQK 1247 +G E+ HGT G+ N A + + L H L + K Sbjct: 297 NGALF--ESVHGTAP------DIAGKDLANPTALLLSAVMMLRH-------MELNTYADK 341 Query: 1248 LEAACVGTVESGK-MTKDL 1301 +E A T++ GK +T DL Sbjct: 342 IERAAFETIKEGKYLTGDL 360
>Q87SS8:LEU3_VIBPA 3-isopropylmalate dehydrogenase - Vibrio parahaemolyticus| Length = 363 Score = 35.8 bits (81), Expect = 0.74 Identities = 42/156 (26%), Positives = 63/156 (40%), Gaps = 1/156 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + + + E Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYE 282 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N +A I S L R L + Q +E+A Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIESAVSKA 330 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAE 1379 + +G++T DLA S L T E D +AE Sbjct: 331 LSAGELTADLA--------SDKPALTTSEMGDKIAE 358
>Q5E857:LEU3_VIBF1 3-isopropylmalate dehydrogenase - Vibrio fischeri (strain ATCC 700601| / ES114) Length = 363 Score = 35.8 bits (81), Expect = 0.74 Identities = 40/149 (26%), Positives = 60/149 (40%), Gaps = 6/149 (4%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ Y H ID+ +K + V C N GD+ SD A GS+ Sbjct: 206 WREVVEEVAKGYPDVTLNHMYIDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSM 265 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S + + E A G+ G+ N +A I S L R L + Sbjct: 266 GMLPSASL-NESNFGLYEPAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGE 316 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDLA 1304 + Q +EAA + +G++T DLA Sbjct: 317 E----EAAQSIEAAVSKALSAGELTADLA 341
>P29696:LEU3_SOLTU 3-isopropylmalate dehydrogenase, chloroplast precursor - Solanum| tuberosum (Potato) Length = 357 Score = 35.8 bits (81), Expect = 0.74 Identities = 43/162 (26%), Positives = 67/162 (41%), Gaps = 1/162 (0%) Frame = +3 Query: 807 KNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACK 983 K I++K DG F ++ E + I YE +ID+ +K+ + V Sbjct: 205 KANIMQKTDGLFLKCCREVAE-------KYPEIKYEEVVIDNCCMMLVKNPALFDVLVMP 257 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSI 1163 N GD+ SDL A G LGL S + +G AEA HG+ G+ N Sbjct: 258 NLYGDIISDLCAGLIGGLGLTPSCNI-GEGGIALAEAVHGSAP------DIAGKNLANPT 310 Query: 1164 ASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKM 1289 A + + + L H L D +++ A + T+ GK+ Sbjct: 311 ALLLSSVSMLRH-------LELHDKADRIQDAILKTIAGGKV 345
>Q7N128:LEU3_PHOLL 3-isopropylmalate dehydrogenase - Photorhabdus luminescens subsp.| laumondii Length = 363 Score = 35.8 bits (81), Expect = 0.74 Identities = 43/148 (29%), Positives = 61/148 (41%), Gaps = 1/148 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVMLCSNIFGDILSDECAMITGSMGMLPSASLNEKGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R L N D +E A Sbjct: 282 PAGGSAP------DIAGKGIANPIAQIL--SAALLLRYSLGHN----DAANAIEQAVNYA 329 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTM 1355 +E G T DLA +G +S D+ +T+ Sbjct: 330 LEQGYRTTDLA--GNGKAISTDEMGSTI 355
>O27441:LEU3_METTH 3-isopropylmalate dehydrogenase - Methanobacterium| thermoautotrophicum Length = 329 Score = 35.8 bits (81), Expect = 0.74 Identities = 45/166 (27%), Positives = 63/166 (37%), Gaps = 1/166 (0%) Frame = +3 Query: 807 KNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACK 983 K +LKK DG F+D F Y+ +A +Y +D Y + + Sbjct: 167 KANVLKKTDGIFRDEF---YKVASEYPQMEATDYY----VDATAMYLITQPQEFQTIVTT 219 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSI 1163 N GD+ SD A G LGL S + + E HG+ Q G+ N Sbjct: 220 NLFGDILSDEAAGLIGGLGLAPSANI--GEKNALFEPVHGSAP------QIAGKNIANPT 271 Query: 1164 ASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDL 1301 A I + L H K + QK+E A T+ G +T DL Sbjct: 272 AMILTTTLMLKHLNKKQE-------AQKIEKALQKTLAEGLVTPDL 310
>P59027:LEU3_BUCPS 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp.| Pemphigus spyrothecae Length = 363 Score = 35.8 bits (81), Expect = 0.74 Identities = 39/162 (24%), Positives = 70/162 (43%), Gaps = 1/162 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID +K+ + V N GD+ SD A GS+G++ S + D E Sbjct: 222 HLYIDHAAMQIIKNPDKFDVILTSNLFGDILSDECAMITGSIGMLPSASL-NDSNFGLYE 280 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + + + + KL + +E+A + T Sbjct: 281 PAGGSAP------DIAGKNIANPIAQILSIAMLVRYTMKLP------MISDHIESAVIDT 328 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRTRL 1397 ++ G T D+A ++KY++T + D +++ L+ R+ Sbjct: 329 LKKGYRTLDIA-------NDKEKYVSTNDIGDIISDILKKRI 363
>P41019:LEU3_BACME 3-isopropylmalate dehydrogenase - Bacillus megaterium| Length = 367 Score = 35.8 bits (81), Expect = 0.74 Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 2/156 (1%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEA 1088 EH L+D +++ + V +N GD+ SD + GSLG++ S + DG ++ Sbjct: 215 EHMLVDSAAMQLIRNPKYFDVVVTENMFGDILSDEASMLTGSLGMLPSASLTADGPSL-Y 273 Query: 1089 EAAHGTVTRHYRVHQKGGETSTNSI-ASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACV 1265 E HG+ G+ N I A+I + + L H L+ + +E A Sbjct: 274 EPVHGSAP------DIAGQNKANPIAAAILSAAMLLRHSFGLEKEAAV------IEQAVE 321 Query: 1266 GTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAV 1373 + +G T DLA + YL T + ++ + Sbjct: 322 SVLHAGHRTADLA--------DGNHYLGTDKMVEVI 349
>Q89XA0:LEU31_BRAJA 3-isopropylmalate dehydrogenase 1 - Bradyrhizobium japonicum| Length = 379 Score = 35.8 bits (81), Expect = 0.74 Identities = 51/221 (23%), Positives = 85/221 (38%), Gaps = 1/221 (0%) Frame = +3 Query: 726 TDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGI 905 T IR A + +A ++ + K +L+ ++++ F D + Sbjct: 170 TTSQIRRVARTAFELARTRKGRVCSVDKANVLET-----SVLWREEVTALHEAEFSDVEL 224 Query: 906 WYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTV 1082 H +D+ +++ + V N GD+ SD A GSLG++ SV + P R Sbjct: 225 --THLYVDNAAMQIVRAPSQFDVMVTCNIFGDILSDCAAMASGSLGMLPSVSLGPPDRLG 282 Query: 1083 EAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAAC 1262 +A + V H G+ N + SI + + L ++ L LE A Sbjct: 283 RRKALYEPV--HGSAPDIAGKGIANPLGSILSVAMMLRITLHRPEDAAL------LEKAV 334 Query: 1263 VGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 + +G T D+A P R L+T E DAV L Sbjct: 335 DTALAAGARTADIA----EPGAKR---LSTQEMGDAVLNAL 368
>P83726:IDHC_NAEFO Isocitrate dehydrogenase [NADP] - Naegleria fowleri| Length = 20 Score = 35.8 bits (81), Expect = 0.74 Identities = 14/18 (77%), Positives = 18/18 (100%) Frame = +3 Query: 180 FEKIQVANPIVEMDGDEM 233 F+KI+VANP+VE+DGDEM Sbjct: 3 FQKIKVANPVVELDGDEM 20
>Q56268:LEU3_THIFE 3-isopropylmalate dehydrogenase - Thiobacillus ferrooxidans| (Acidithiobacillus ferrooxidans) Length = 358 Score = 35.4 bits (80), Expect = 0.97 Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H +D+ +++ + V N GD+ SD +Q GS+G++ S + +GR + E Sbjct: 218 HMYVDNAAMQLIRAPAQFDVLLTGNMFGDILSDEASQLTGSIGMLPSASL-GEGRAM-YE 275 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 HG+ G+ N +A+I + + L H + + Q++EAA Sbjct: 276 PIHGSAP------DIAGQDKANPLATILSVAMMLRHSLNAE------PWAQRVEAAVQRV 323 Query: 1272 VESGKMTKDLA 1304 ++ G T D+A Sbjct: 324 LDQGLRTADIA 334
>Q24XT2:LEU3_DESHY 3-isopropylmalate dehydrogenase - Desulfitobacterium hafniense| (strain Y51) Length = 352 Score = 35.4 bits (80), Expect = 0.97 Identities = 38/158 (24%), Positives = 69/158 (43%), Gaps = 1/158 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H +D+ +++ + V +N GD+ +DL + GS+G+++S + G E Sbjct: 216 HMYVDNAAMQLVRNPKQFDVIVTENMFGDILTDLASMLGGSIGMLSSASL--SGTQGMYE 273 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 AHG+ G+ N +A+I + + L + ++ ++E+A Sbjct: 274 PAHGSAP------DIAGKNLANPLATILSAALMLRYSFGMEAE------ALRIESAVEKV 321 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 +E G T DLA + DK + T+E DAV L Sbjct: 322 LEQGYRTGDLA-------QAGDKVVGTIEMGDAVLAAL 352
>O85071:LEU3_BUCDN 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp.| Diuraphis noxia Length = 363 Score = 35.4 bits (80), Expect = 0.97 Identities = 40/160 (25%), Positives = 67/160 (41%), Gaps = 2/160 (1%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID++ +K + V C N GD+ SD A GS+G++ S + + E Sbjct: 223 HLYIDNVCMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASLNEKNFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + S + + L+ K++ A + Sbjct: 282 PAGGSAP------DIQGKNIANPIAQILSLSMLIRYSMNLN------KIANKIDNAVINV 329 Query: 1272 VESGKMTKDLALLIHGPTVSRDK-YLNTMEFIDAVAEELR 1388 ++ G T D +S+D+ YL T E D +A+ L+ Sbjct: 330 LKKGYKTMD---------ISKDQNYLKTNEMGDVIADFLK 360
>Q63DX7:LEU3_BACCZ 3-isopropylmalate dehydrogenase - Bacillus cereus (strain ZK / E33L)| Length = 354 Score = 35.4 bits (80), Expect = 0.97 Identities = 36/148 (24%), Positives = 60/148 (40%), Gaps = 6/148 (4%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ + Y EH L+D +++ G + V +N GD+ SD + GSL Sbjct: 193 WRTVTEEVALRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSL 252 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S G ++ E HG+ ++ S+A + S GL Sbjct: 253 GMLPSASHAEKGPSL-YEPIHGSAPDIAGKNKANPIAMMRSVAMMLGQSFGLTREG---- 307 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDL 1301 +E A ++SGK T+D+ Sbjct: 308 --------CAIEEAISAVLKSGKCTEDI 327
>Q81G11:LEU3_BACCR 3-isopropylmalate dehydrogenase - Bacillus cereus (strain ATCC 14579| / DSM 31) Length = 354 Score = 35.4 bits (80), Expect = 0.97 Identities = 36/148 (24%), Positives = 59/148 (39%), Gaps = 6/148 (4%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ + Y EH L+D +++ G + V +N GD+ SD + GSL Sbjct: 193 WRTVTEEVALRYPNVEVEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSL 252 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S G ++ E HG+ ++ S+A + S GL Sbjct: 253 GMLPSASHAEKGPSL-YEPIHGSAPDIAGKNKANPIAMMRSVAMMLGQSFGLTREG---- 307 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDL 1301 +E A ++SGK T D+ Sbjct: 308 --------YAIEEAVSAVLKSGKCTADI 327
>O34296:TTUC3_AGRVI Probable tartrate dehydrogenase/decarboxylase ttuC' - Agrobacterium| vitis (Rhizobium vitis) Length = 358 Score = 35.0 bits (79), Expect = 1.3 Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 8/150 (5%) Frame = +3 Query: 903 IWYEHRLIDDM-VAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 1079 + ++ L+D M V LK E N D+ SDL GSLG+ + + P+ R Sbjct: 214 VTWDKMLVDAMTVRMTLKPETLDTIVATNLHADILSDLAGALAGSLGVAPTANIDPERRF 273 Query: 1080 VEA-EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEA 1256 E HG+ + + KG N IA+ + + L H + D RL+ +++ Sbjct: 274 PSMFEPIHGSA---FDITGKG---IANPIATFWTAAQMLEHLGERDAAARLMSAVERVTE 327 Query: 1257 ACV------GTVESGKMTKDLALLIHGPTV 1328 A + GT + ++T+ + I G + Sbjct: 328 AGILTPDVGGTANTSQVTEAVCNAIAGSNI 357
>Q5SIY4:LEU3_THET8 3-isopropylmalate dehydrogenase - Thermus thermophilus (strain HB8 /| ATCC 27634 / DSM 579) Length = 345 Score = 35.0 bits (79), Expect = 1.3 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 7/115 (6%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ G Y EH+ +D M + ++S + V N GD+ SDL + GSL Sbjct: 195 WRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSL 254 Query: 1038 GLMTSVLVCPDGR-TVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAH 1199 GL+ S + GR T E HG+ G+ N A+I + + L H Sbjct: 255 GLLPSASL---GRGTPVFEPVHGSAP------DIAGKGIANPTAAILSAAMMLEH 300
>P61494:LEU3_THET2 3-isopropylmalate dehydrogenase - Thermus thermophilus (strain HB27 /| ATCC BAA-163 / DSM 7039) Length = 345 Score = 35.0 bits (79), Expect = 1.3 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 7/115 (6%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ G Y EH+ +D M + ++S + V N GD+ SDL + GSL Sbjct: 195 WRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSL 254 Query: 1038 GLMTSVLVCPDGR-TVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAH 1199 GL+ S + GR T E HG+ G+ N A+I + + L H Sbjct: 255 GLLPSASL---GRGTPVFEPVHGSAP------DIAGKGLANPTAAILSAAMMLEH 300
>Q9EVG6:LEU3_BUCUA 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp.| Uroleucon aeneum Length = 363 Score = 35.0 bits (79), Expect = 1.3 Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 1/158 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + + + E Sbjct: 223 HLYIDNATMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + S + + L K++ D K++ + + Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSLSMLVRYSMNL---KKIAD---KIDQSVISV 329 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 ++ G T D++ + + YL T E D +A L Sbjct: 330 LKKGYRTADIS--------NNNDYLKTNEMGDVIASAL 359
>P12010:LEU3_BACCO 3-isopropylmalate dehydrogenase - Bacillus coagulans| Length = 366 Score = 35.0 bits (79), Expect = 1.3 Identities = 50/232 (21%), Positives = 94/232 (40%), Gaps = 1/232 (0%) Frame = +3 Query: 693 GAGGVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYET 872 G V ++ T E I E + +A +R L K +L+ +++I ++ + Sbjct: 152 GENEVVDTLAYTREEIERIIEKAFQLAQIRRKKLASVDKANVLES-SRMWREIAEETAK- 209 Query: 873 NWRCRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMT 1049 ++ D + H L+D + + G + V +N GD+ SD + GSLG++ Sbjct: 210 ----KYPDVEL--SHMLVDSTSMQLIANPGQFDVIVTENMFGDILSDEASVITGSLGMLP 263 Query: 1050 SVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRL 1229 S + D R E HG+ G+ N + ++ + + L + L+ Sbjct: 264 SASLRSD-RFGMYEPVHGSAP------DIAGQGKANPLGTVLSAALMLRYSFGLEKE--- 313 Query: 1230 LDFTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 +E A ++ G T DL V+ K ++T+E D + E+L Sbjct: 314 ---AAAIEKAVDDVLQDGYCTGDL-------QVANGKVVSTIELTDRLIEKL 355
>O66607:LEU3_AQUAE 3-isopropylmalate dehydrogenase - Aquifex aeolicus| Length = 364 Score = 35.0 bits (79), Expect = 1.3 Identities = 56/255 (21%), Positives = 98/255 (38%), Gaps = 6/255 (2%) Frame = +3 Query: 612 IIRGTGKLKL--IFDGIEEQIELDVFNFSGAGGVALSMYNTDESIRAFAEASMNMAYQKR 785 +++GT + + + GI +F +G +M T++ IR +A ++R Sbjct: 125 VVKGTDMIVIRELTSGIYYGEPRGIFEENGKRYAINTMKYTEDEIRRIVRKGFEIARKRR 184 Query: 786 WPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFEDAGIWYEHRLIDDMVAYALKSEGG 965 L K +L+ ++ I ++ E + D + EH ID+ ++ Sbjct: 185 KKLTSVDKANVLE-VSALWRQIVEEEKEN-----YPDVEL--EHLYIDNCAMQLVRRPTS 236 Query: 966 Y-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGG 1142 + V N GD+ SD GSLG++ S + R E HG+ G Sbjct: 237 FDVIVTGNIFGDILSDEAGVVVGSLGMLPSASI--GDRYALYEPVHGSAP------DIAG 288 Query: 1143 ETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDL---ALLI 1313 + N IA+I + + L + +D L +E A T+ G T D+ + Sbjct: 289 KGIANPIATILSAAMMLKYSFNMDKAHDL------IEKAIEETLNQGYRTPDIYSEGCIK 342 Query: 1314 HGPTVSRDKYLNTME 1358 G DK L +E Sbjct: 343 VGTKEITDKILENLE 357
>O34295:TTUC5_AGRVI Probable tartrate dehydrogenase/decarboxylase ttuC' - Agrobacterium| vitis (Rhizobium vitis) Length = 358 Score = 34.7 bits (78), Expect = 1.7 Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 8/150 (5%) Frame = +3 Query: 903 IWYEHRLIDDM-VAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 1079 + ++ L+D M V LK E N D+ SDL GSLG+ + + P+ R Sbjct: 214 VTWDKMLVDAMTVRMTLKPETLDTIVATNLHADILSDLAGALAGSLGVAPTANIDPERRF 273 Query: 1080 VEA-EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEA 1256 E HG+ + + KG N IA+ + + L H + D RL+ +++ Sbjct: 274 PSMFEPIHGSA---FDITGKG---IANPIATFWTAAQMLEHLGERDAAARLMGAVERVTE 327 Query: 1257 ACV------GTVESGKMTKDLALLIHGPTV 1328 A + GT + ++T+ + I G + Sbjct: 328 AGILTPDVGGTANTSQVTEAVCNAIAGSNI 357
>P70792:TTUC4_AGRVI Probable tartrate dehydrogenase/decarboxylase ttuC' - Agrobacterium| vitis (Rhizobium vitis) Length = 358 Score = 34.7 bits (78), Expect = 1.7 Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 2/163 (1%) Frame = +3 Query: 903 IWYEHRLIDDM-VAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 1079 + ++ L+D M V LK + N D+ SDL GSLG+ + + P+ R Sbjct: 214 VTWDKMLVDAMTVRMTLKPQSLDTIVATNLHADILSDLAGALAGSLGVAPTANIDPERRF 273 Query: 1080 VEA-EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEA 1256 E HG+ + + KG N +A+ + + L H + D RL+ +++ Sbjct: 274 PSMFEPIHGSA---FDITGKG---IANPVATFWTAAQMLEHLGEKDAATRLMSAVERV-- 325 Query: 1257 ACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 E+G +T D+ G T NT + DAV E + Sbjct: 326 -----TEAGILTPDV-----GGTA------NTQQVTDAVCEAI 352
>Q4L7U1:LEU3_STAHJ 3-isopropylmalate dehydrogenase - Staphylococcus haemolyticus (strain| JCSC1435) Length = 346 Score = 34.7 bits (78), Expect = 1.7 Identities = 46/197 (23%), Positives = 77/197 (39%), Gaps = 1/197 (0%) Frame = +3 Query: 714 SMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFE 893 S+ T + I A + +A Q++ L K +L K I + ++E F Sbjct: 154 SLTYTKKEIERIAMVAFELASQRKKKLTSVDKENVLATSKLWRKTINEISHE------FP 207 Query: 894 DAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPD 1070 D + H L+D + + V +N GD+ SD + GSLGL S + Sbjct: 208 DVKV--NHLLVDACSMQLISQPTNFDVIVTENLFGDILSDEASTIPGSLGLSPSASFSLE 265 Query: 1071 GRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKL 1250 G + + +H + + ++A+ F LA L ++ D +L Sbjct: 266 GPRL-----------YEPIHGSAPDIANQNLANPFGMILSLA--MCLRESFNFEDAASEL 312 Query: 1251 EAACVGTVESGKMTKDL 1301 E A ++ GK TKDL Sbjct: 313 EQAVYQLIKDGKTTKDL 329
>Q83SP1:LEU3_SHIFL 3-isopropylmalate dehydrogenase - Shigella flexneri| Length = 363 Score = 34.7 bits (78), Expect = 1.7 Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD + D +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAD----DAASAIERAINRA 329 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 330 LEEGIRTGDLA 340
>Q1RGC4:LEU3_ECOUT 3-isopropylmalate dehydrogenase - Escherichia coli (strain UTI89 /| UPEC) Length = 364 Score = 34.7 bits (78), Expect = 1.7 Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 224 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 282 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD + D +E A Sbjct: 283 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAD----DAASAIERAINRA 330 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 331 LEEGIRTGDLA 341
>Q8FL76:LEU3_ECOL6 3-isopropylmalate dehydrogenase - Escherichia coli O6| Length = 363 Score = 34.7 bits (78), Expect = 1.7 Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD + D +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAD----DAASAIERAINRA 329 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 330 LEEGIRTGDLA 340
>Q8X9Z9:LEU3_ECO57 3-isopropylmalate dehydrogenase - Escherichia coli O157:H7| Length = 363 Score = 34.7 bits (78), Expect = 1.7 Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD + D +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAD----DAASAIERAINRA 329 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 330 LEEGIRTGDLA 340
>Q9ABN3:LEU3_CAUCR 3-isopropylmalate dehydrogenase - Caulobacter crescentus (Caulobacter| vibrioides) Length = 350 Score = 34.7 bits (78), Expect = 1.7 Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 1/131 (0%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEA 1088 EH L D+ +++ + V N GD+ SD A GSLG++ S + G+ Sbjct: 215 EHILADNCAMQLVRAPKQFDVIVTDNLFGDILSDAAAMLTGSLGMLPSAALGAPGKPGLY 274 Query: 1089 EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVG 1268 E HG+ G+ N +A+I ++ L K + L AA Sbjct: 275 EPIHGSAP------DIAGKGLANPLAAILSFEMALRWSLK------QTEAADALLAAVKA 322 Query: 1269 TVESGKMTKDL 1301 +++G T+DL Sbjct: 323 ALDNGARTRDL 333
>Q6HLF2:LEU3_BACHK 3-isopropylmalate dehydrogenase - Bacillus thuringiensis subsp.| konkukian Length = 354 Score = 34.7 bits (78), Expect = 1.7 Identities = 36/148 (24%), Positives = 59/148 (39%), Gaps = 6/148 (4%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ + Y EH L+D +++ G + V +N GD+ SD + GSL Sbjct: 193 WRTVTEEVALRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSL 252 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S G ++ E HG+ ++ S+A + S GL Sbjct: 253 GMLPSASHAEKGPSL-YEPIHGSAPDIAGKNKANPIAMMRSVAMMLGQSFGLTREG---- 307 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDL 1301 +E A ++SGK T D+ Sbjct: 308 --------CAIEEAISAVLKSGKCTADI 327
>Q81T67:LEU3_BACAN 3-isopropylmalate dehydrogenase - Bacillus anthracis| Length = 354 Score = 34.7 bits (78), Expect = 1.7 Identities = 36/148 (24%), Positives = 59/148 (39%), Gaps = 6/148 (4%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ + Y EH L+D +++ G + V +N GD+ SD + GSL Sbjct: 193 WRIVTEEVALRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSL 252 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S G ++ E HG+ ++ S+A + S GL Sbjct: 253 GMLPSASHAEKGPSL-YEPIHGSAPDIAGKNKANPIAMMRSVAMMLGQSFGLTREG---- 307 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDL 1301 +E A ++SGK T D+ Sbjct: 308 --------CAIEEAISAVLKSGKCTADI 327
>Q44471:TTUC1_AGRVI Probable tartrate dehydrogenase/decarboxylase ttuC - Agrobacterium| vitis (Rhizobium vitis) Length = 364 Score = 34.3 bits (77), Expect = 2.2 Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 8/150 (5%) Frame = +3 Query: 903 IWYEHRLIDDM-VAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 1079 + ++ L+D M V LK E N D+ SDL GSLG+ + + P+ R Sbjct: 214 VTWDKMLVDAMTVRMTLKPETLDTIVATNLHADILSDLAGALAGSLGVAPTANIDPERRF 273 Query: 1080 VEA-EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEA 1256 E HG+ + + KG N IA+ + + L H + D RL+ +++ Sbjct: 274 PSMFEPIHGSA---FDITGKG---IANPIATFWTAAQMLEHLGERDAAARLMSAVERVTE 327 Query: 1257 ACV------GTVESGKMTKDLALLIHGPTV 1328 A + GT + ++T+ + I G + Sbjct: 328 AGILTPDVGGTANTRQVTEAVCNAIAGSNI 357
>Q92KY8:LEU3_RHIME 3-isopropylmalate dehydrogenase - Rhizobium meliloti (Sinorhizobium| meliloti) Length = 370 Score = 34.3 bits (77), Expect = 2.2 Identities = 52/232 (22%), Positives = 92/232 (39%), Gaps = 2/232 (0%) Frame = +3 Query: 702 GVALSMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWR 881 G+ +Y+T E I A + +A + + K ++K ++ Q + Sbjct: 159 GIDTQVYDTYE-IERIAGVAFELARTRNNRVCSMEKRNVMKS-----GVLWNQVVTETHK 212 Query: 882 CRFEDAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSV- 1055 ++ D + EH L D ++ + V N GD+ SD+ A GSLG++ S Sbjct: 213 AKYSDVQL--EHMLADAGGMQLVRQPKQFDVIVTDNLFGDMLSDVAAMLTGSLGMLPSAS 270 Query: 1056 LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLD 1235 L PD +T + +A + V H G N IA I +++ L + + L+ Sbjct: 271 LGAPDAKTGKRKALYEPV--HGSAPDIAGTGVANPIAMIASFAMCLRY------SFNLVK 322 Query: 1236 FTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELRT 1391 LE A ++ G T D+ + + T E DA+ E ++ Sbjct: 323 EADDLEKAIANVLDQGIRTGDI-------MAEGCRKVGTAEMGDAILAEFKS 367
>Q2RGA0:LEU3_MOOTA 3-isopropylmalate dehydrogenase - Moorella thermoacetica (strain ATCC| 39073) Length = 357 Score = 34.3 bits (77), Expect = 2.2 Identities = 45/202 (22%), Positives = 73/202 (36%), Gaps = 6/202 (2%) Frame = +3 Query: 714 SMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFE 893 +MY T I + +A Q+R L K +L WR E Sbjct: 159 TMYYTRAEIERIVRLAFTIARQRRCHLTSVDKANVLTT-------------SRLWRDTVE 205 Query: 894 DAG-----IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSV 1055 D + EH +D+ ++ + V +N GD+ SD + GS+G++ S Sbjct: 206 DIKGEFPEVTVEHMYVDNCAMQLVRRPAQFDVIVTENTFGDILSDQASVLTGSIGMLPSA 265 Query: 1056 LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLD 1235 + G E HG+ G+ N +A+I + + L + K+D Sbjct: 266 SI--GGAVALYEPCHGSAP------DIAGQQKANPLATILSAAMMLKYSFKMD------Q 311 Query: 1236 FTQKLEAACVGTVESGKMTKDL 1301 +EAA + G T DL Sbjct: 312 AAAAIEAAVGRVLAKGYRTPDL 333
>P24015:LEU3_LEPIN 3-isopropylmalate dehydrogenase - Leptospira interrogans| Length = 358 Score = 34.3 bits (77), Expect = 2.2 Identities = 28/109 (25%), Positives = 50/109 (45%) Frame = +3 Query: 978 CKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTN 1157 C+N GD+ SD + GS+G++ S + G + E + G+ G+ N Sbjct: 243 CENMFGDILSDEASIITGSIGMLPSASLSESGFGL-YEPSGGSAP------DIAGKGVAN 295 Query: 1158 SIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDLA 1304 IA + + + L + +++ K+E A T+ SGK T+D+A Sbjct: 296 PIAQVLSAALMLRYSFSMEEE------ANKIETAVRKTIASGKRTRDIA 338
>Q72RH7:LEU3_LEPIC 3-isopropylmalate dehydrogenase - Leptospira interrogans serogroup| Icterohaemorrhagiae serovar copenhageni Length = 358 Score = 34.3 bits (77), Expect = 2.2 Identities = 28/109 (25%), Positives = 50/109 (45%) Frame = +3 Query: 978 CKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTN 1157 C+N GD+ SD + GS+G++ S + G + E + G+ G+ N Sbjct: 243 CENMFGDILSDEASIITGSIGMLPSASLSESGFGL-YEPSGGSAP------DIAGKGVAN 295 Query: 1158 SIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDLA 1304 IA + + + L + +++ K+E A T+ SGK T+D+A Sbjct: 296 PIAQVLSAALMLRYSFSMEEE------ANKIETAVRKTIASGKRTRDIA 338
>Q3APC4:LEU3_CHLCH 3-isopropylmalate dehydrogenase - Chlorobium chlorochromatii (strain| CaD3) Length = 352 Score = 34.3 bits (77), Expect = 2.2 Identities = 35/135 (25%), Positives = 57/135 (42%) Frame = +3 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSI 1163 N GD+ SD+ GSLG++ S + + E HG+ G+ N I Sbjct: 239 NLFGDILSDISGMITGSLGMLPSASI--GSKHALYEPIHGSAP------DIAGQNKANPI 290 Query: 1164 ASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDKY 1343 A+I + + H K D R D Q +EAA + +G T D+A + D Sbjct: 291 ATIASVAMMFEHSFKRTDIAR--DIEQAIEAA----LATGVRTADIA-------AAGDTA 337 Query: 1344 LNTMEFIDAVAEELR 1388 ++T +A+ +L+ Sbjct: 338 VSTTAMTEAIISQLK 352
>P56260:QIN_AVIS3 Transforming protein Qin - Avian sarcoma virus (strain 31) (ASV31)| Length = 387 Score = 33.9 bits (76), Expect = 2.8 Identities = 15/39 (38%), Positives = 20/39 (51%) Frame = -2 Query: 1041 DLTIQNLEQLDRSAHLHHNSCKPKHSHLHSLGHRPPYHQ 925 +L + ++ + S H HHNS P H H H H PP Q Sbjct: 22 NLVPEAVQSDNHSGHSHHNSHHPHHHHHHHHHHPPPPQQ 60
>Q67JY2:LEU3_SYMTH 3-isopropylmalate dehydrogenase - Symbiobacterium thermophilum| Length = 368 Score = 33.9 bits (76), Expect = 2.8 Identities = 42/160 (26%), Positives = 60/160 (37%), Gaps = 2/160 (1%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSV-LVCPDGRTVE 1085 EH L D+ L+ G + V N GD SD A GS+GL+ S L R Sbjct: 223 EHLLADNAAMQILRRPGDFDVMLASNLFGDFLSDEAAMLTGSIGLLPSASLGAARNRFGL 282 Query: 1086 AEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACV 1265 + + + H G+ N +A+I + L H +D R +E A Sbjct: 283 PKGFYEPI--HGSAPDIAGQDRANPLAAILCGAMLLRHSLGREDAAR------AVEQAVA 334 Query: 1266 GTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 +E G T D+ TV L T AVA+ + Sbjct: 335 AVLEEGLRTADI-------TVPGTAVLGTAAMARAVADRV 367
>O31292:LEU3_BUCTS 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp. Thelaxes| suberi Length = 364 Score = 33.9 bits (76), Expect = 2.8 Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 1/101 (0%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEA 1088 EH ID+ +K+ + V C N GD+ SD A GS+GL+ S + G + Sbjct: 222 EHMYIDNATMELIKNPSSFDVILCSNLFGDIISDECAAIIGSIGLLPSASLNKSGFGL-Y 280 Query: 1089 EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKL 1211 E A G+ G+T N IA I + S L + L Sbjct: 281 EPAGGSAP------NIAGKTIANPIAQILSLSMLLKYSLHL 315
>P05645:LEU3_BACSU 3-isopropylmalate dehydrogenase - Bacillus subtilis| Length = 365 Score = 33.9 bits (76), Expect = 2.8 Identities = 38/149 (25%), Positives = 62/149 (41%), Gaps = 6/149 (4%) Frame = +3 Query: 876 WRCRFEDAG-----IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR ED + EH L+D+ + + + V +N GD+ SD + GSL Sbjct: 202 WREVAEDVAQEFPDVKLEHMLVDNAAMQLIYAPNQFDVVVTENMFGDILSDEASMLTGSL 261 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S + G + E HG+ G+ N A+I + + L L++ Sbjct: 262 GMLPSASLSSSGLHL-FEPVHGSAP------DIAGKGMANPFAAILSAAMLLRTSFGLEE 314 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDLA 1304 + +E A + SGK T+DLA Sbjct: 315 E------AKAVEDAVNKVLASGKRTRDLA 337
>Q90964:FOXG1_CHICK Forkhead box protein G1 - Gallus gallus (Chicken)| Length = 451 Score = 33.5 bits (75), Expect = 3.7 Identities = 14/29 (48%), Positives = 15/29 (51%) Frame = -2 Query: 1011 DRSAHLHHNSCKPKHSHLHSLGHRPPYHQ 925 + S H HHNS P H H H H PP Q Sbjct: 32 NHSGHSHHNSHHPHHHHHHHHHHPPPPQQ 60
>P70787:TTUC2_AGRVI Probable tartrate dehydrogenase/decarboxylase ttuC - Agrobacterium| vitis (Rhizobium vitis) Length = 364 Score = 33.5 bits (75), Expect = 3.7 Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 8/150 (5%) Frame = +3 Query: 903 IWYEHRLIDDM-VAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 1079 + ++ L+D M V LK + N D+ SDL GSLG+ + + P+ R Sbjct: 214 VTWDKMLVDAMTVRMTLKPQSLDTIVATNLHADILSDLAGALAGSLGVAPTANIDPERRF 273 Query: 1080 VEA-EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEA 1256 E HG+ + + KG N +A+ + + L H + D RL+ +++ Sbjct: 274 PSMFEPIHGSA---FDITGKG---IANPVATFWTAAQMLEHLGEKDAATRLMSAVERVTE 327 Query: 1257 ACV------GTVESGKMTKDLALLIHGPTV 1328 A + GT ++ ++T + I G + Sbjct: 328 AGILTPDVGGTADTQQVTDAVCEAIAGSNI 357
>Q3Z5T7:LEU3_SHISS 3-isopropylmalate dehydrogenase - Shigella sonnei (strain Ss046)| Length = 363 Score = 33.5 bits (75), Expect = 3.7 Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD + D +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAD----DAACAIERAINRA 329 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 330 LEEGIRTGDLA 340
>Q2J3B4:LEU3_RHOP2 3-isopropylmalate dehydrogenase - Rhodopseudomonas palustris (strain| HaA2) Length = 370 Score = 33.5 bits (75), Expect = 3.7 Identities = 44/161 (27%), Positives = 71/161 (44%), Gaps = 2/161 (1%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSV-LVCPDGRTVE 1085 EH+L D +K + V N GD+ SD+ A GSLG++ S L D T + Sbjct: 221 EHQLADSGGMNLVKWPKQFDVIVTDNLFGDMLSDIAAMLTGSLGMLPSASLGAVDDTTGK 280 Query: 1086 AEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACV 1265 +A + V H G+ N +A + S G+A R LD + + KL+ A Sbjct: 281 RKAMYEPV--HGSAPDIAGKGLANPVAMLA--SFGMALRYSLD----MGELADKLDEAIA 332 Query: 1266 GTVESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEELR 1388 + G T D+ G TV ++T + +A+ +E++ Sbjct: 333 VVLARGLRTADIK--SEGSTV-----VSTSQMGEAIVQEMQ 366
>Q46LE2:LEU3_PROMT 3-isopropylmalate dehydrogenase - Prochlorococcus marinus (strain| NATL2A) Length = 359 Score = 33.5 bits (75), Expect = 3.7 Identities = 32/132 (24%), Positives = 55/132 (41%), Gaps = 1/132 (0%) Frame = +3 Query: 714 SMYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFE 893 +M T E + AE + +A Q+ + K +L D+ Q E + Sbjct: 161 TMTYTSEEVNRIAEIAFKLAKQRNQKVCSVDKANVL--------DVSQLWREETILVSNK 212 Query: 894 DAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPD 1070 I H+ +D+ +++ + V N GD+ SD+ A GS+G++ S + D Sbjct: 213 YKDIELTHQYVDNAAMQLVRNPSQFDVILTGNLFGDILSDIAAMLTGSIGMLPSASLTTD 272 Query: 1071 GRTVEAEAAHGT 1106 G V E HG+ Sbjct: 273 GPGV-FEPVHGS 283
>Q4QLS3:LEU3_HAEI8 3-isopropylmalate dehydrogenase - Haemophilus influenzae (strain| 86-028NP) Length = 358 Score = 33.5 bits (75), Expect = 3.7 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 1/132 (0%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEA 1088 EH ID+ +K+ + V C N GD+ SD A GS+G++ S + G + Sbjct: 221 EHIYIDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEAGFGL-Y 279 Query: 1089 EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVG 1268 E A G+ G+ N IA I + + L + L+ + +E+A Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAADAIESAVQK 327 Query: 1269 TVESGKMTKDLA 1304 + SG T DLA Sbjct: 328 VLASGHRTADLA 339
>P30125:LEU3_ECOLI 3-isopropylmalate dehydrogenase - Escherichia coli| Length = 363 Score = 33.5 bits (75), Expect = 3.7 Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD + D +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAD----DAACAIERAINRA 329 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 330 LEEGIRTGDLA 340
>Q6ANR1:LEU3_DESPS 3-isopropylmalate dehydrogenase - Desulfotalea psychrophila| Length = 357 Score = 33.5 bits (75), Expect = 3.7 Identities = 38/139 (27%), Positives = 57/139 (41%) Frame = +3 Query: 969 VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGET 1148 V C N GD+ SD A GS+GL+ S + + + E A G+ G+ Sbjct: 239 VMLCGNMFGDIISDEAAMLTGSMGLLASASLNTENFGL-FEPAGGSAP------DIAGQG 291 Query: 1149 STNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDLALLIHGPTV 1328 N IA I + + L + + +EAA T++ G T D+A V Sbjct: 292 IANPIAEILSAAMMLRYSLGYG------EAADAIEAAVEKTLDRGICTADIA-------V 338 Query: 1329 SRDKYLNTMEFIDAVAEEL 1385 R + +NT E DA+ L Sbjct: 339 DRSQAVNTAEMGDAIVAAL 357
>Q9EVG9:LEU3_BUCUM 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp.| Uroleucon ambrosiae Length = 365 Score = 33.5 bits (75), Expect = 3.7 Identities = 38/158 (24%), Positives = 67/158 (42%), Gaps = 1/158 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + + C N GD+ SD A GS+G++ S + + + E Sbjct: 225 HLYIDNATMQIIKDPNQFDILLCSNLFGDIVSDECAIITGSIGMLPSASL-NEKKFGLYE 283 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + S + + L K++ D K++ + + Sbjct: 284 PAGGSAP------DIEGKNIANPIAQILSVSMLVRYGMNL---KKIAD---KIDQSVISV 331 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 ++ G T D++ + + YL T E D +A L Sbjct: 332 LKKGYRTADIS--------NNNNYLKTNEMGDVIANTL 361
>Q9K8E9:LEU3_BACHD 3-isopropylmalate dehydrogenase - Bacillus halodurans| Length = 363 Score = 33.5 bits (75), Expect = 3.7 Identities = 36/135 (26%), Positives = 57/135 (42%), Gaps = 4/135 (2%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEA 1088 EH L+D+ ++ + V +N GD+ SD + GSLG++ S + DG + Sbjct: 218 EHMLVDNAAMQLIRRPKQFDVLVTENLFGDILSDEASMVTGSLGMLPSASLTSDGPGL-Y 276 Query: 1089 EAAHGTVTRHYRVHQKGGETSTNSIAS---IFAWSTGLAHRAKLDDNKRLLDFTQKLEAA 1259 E HG+ + KG +IAS + +S GL AK +E A Sbjct: 277 EPIHGSAP---DIAGKGVANPLATIASCAMMLKYSFGLHEEAK------------TIEDA 321 Query: 1260 CVGTVESGKMTKDLA 1304 ++ G T D+A Sbjct: 322 IEAVLKQGYRTADIA 336
>Q6D0G7:LEU3_ERWCT 3-isopropylmalate dehydrogenase - Erwinia carotovora subsp.| atroseptica (Pectobacterium atrosepticum) Length = 363 Score = 33.1 bits (74), Expect = 4.8 Identities = 40/155 (25%), Positives = 59/155 (38%), Gaps = 1/155 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HLYIDNATMQLIKDPSQFDVMLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + + L + D D + +E A Sbjct: 282 PAGGSAP------DIAGKDIANPIAQILSLALLLRYSLGAD------DAAEAIEKAVNTA 329 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVA 1376 + G T DLA S + T E D +A Sbjct: 330 LAEGYRTADLA--------SASNAIGTSEMGDVIA 356
>Q9EVI4:LEU3_BUCUS 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp.| Uroleucon solidaginis Length = 363 Score = 33.1 bits (74), Expect = 4.8 Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 1/158 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K+ + + C N GD+ SD A GS+G++ S + + + E Sbjct: 223 HLYIDNATMQIIKNPNQFDILLCSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + S + + L K + D K++ + + Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSVSMLVRYSMNL---KTIAD---KIDQSVISV 329 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 ++ G T D++ + YL T E D +A L Sbjct: 330 LKKGYRTADIS--------NNSHYLKTNEMGDVIASAL 359
>Q5NPQ9:LEU3_ZYMMO 3-isopropylmalate dehydrogenase - Zymomonas mobilis| Length = 349 Score = 32.7 bits (73), Expect = 6.3 Identities = 31/130 (23%), Positives = 56/130 (43%), Gaps = 1/130 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H +D+ +++ + V N GD+ SDL + GS+GL+ S + +G+ + E Sbjct: 215 HMYVDNAAMQLVRAPDQFDVIVTGNLFGDILSDLASACVGSIGLLPSASLNSEGKGL-YE 273 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 HG+ G N +A+I + + L + K + + ++E A Sbjct: 274 PIHGSAP------DIAGLGKANPLATILSGAMMLRYSLKREAD------ADRIEKAVSTA 321 Query: 1272 VESGKMTKDL 1301 +E G T DL Sbjct: 322 LEKGARTADL 331
>Q8ZIG9:LEU3_YERPE 3-isopropylmalate dehydrogenase - Yersinia pestis| Length = 363 Score = 32.7 bits (73), Expect = 6.3 Identities = 36/131 (27%), Positives = 51/131 (38%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + + L D D +E A Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLTLLLRFSLGKD------DAADAIERAINQA 329 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 330 LEQGYRTADLA 340
>P61495:LEU3_THETH 3-isopropylmalate dehydrogenase - Thermus thermophilus| Length = 345 Score = 32.7 bits (73), Expect = 6.3 Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 7/115 (6%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ G Y EH+ +D + ++S + V N GD+ SDL + GSL Sbjct: 195 WRKTVEEVGRGYPDVALEHQYVDAAAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSL 254 Query: 1038 GLMTSVLVCPDGR-TVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAH 1199 GL+ S + GR T E HG+ G+ N A+I + + L H Sbjct: 255 GLLPSASL---GRGTPVFEPVHGSAP------DIAGKGIANPTAAILSAAMMLEH 300
>Q326G2:LEU3_SHIBS 3-isopropylmalate dehydrogenase - Shigella boydii serotype 4 (strain| Sb227) Length = 363 Score = 32.7 bits (73), Expect = 6.3 Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + G + E Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I S L R LD + D +E A Sbjct: 282 PAGGSAP------DITGKNIANPIAQIL--SLALLLRYSLDAD----DAACAIERAINRA 329 Query: 1272 VESGKMTKDLA 1304 +E G T DLA Sbjct: 330 LEEGIRTGDLA 340
>Q7V1R9:LEU3_PROMP 3-isopropylmalate dehydrogenase - Prochlorococcus marinus subsp.| pastoris (strain CCMP 1378 / MED4) Length = 357 Score = 32.7 bits (73), Expect = 6.3 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 1/127 (0%) Frame = +3 Query: 924 IDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAH 1100 +D+ +K G + V N GD+ SDL A GS+G++ S + G V E H Sbjct: 223 VDNAAMQLVKDPGQFDVILTSNLFGDILSDLAAMITGSIGMLPSASLSNSGPGV-FEPVH 281 Query: 1101 GTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVES 1280 G+ G+ N IA A ST + + L++ ++ +E A + Sbjct: 282 GSAP------DIAGKNIANPIA--MALSTSMMLKIGLNE----IEAADDIEIAIDNVLSK 329 Query: 1281 GKMTKDL 1301 G T DL Sbjct: 330 GYRTSDL 336
>Q9CJN6:LEU3_PASMU 3-isopropylmalate dehydrogenase - Pasteurella multocida| Length = 359 Score = 32.7 bits (73), Expect = 6.3 Identities = 36/132 (27%), Positives = 53/132 (40%), Gaps = 1/132 (0%) Frame = +3 Query: 912 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEA 1088 +H ID+ +K + V C N GD+ SD A GS+G++ S + G + Sbjct: 221 DHIYIDNATMQLIKQPEFFDVLLCSNIFGDIISDECAMITGSMGMLPSASLNEKGFGL-Y 279 Query: 1089 EAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVG 1268 E A G+ G+ N IA I + + L H L+ D +E A Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRHSFNLN------DAATAIENAVKN 327 Query: 1269 TVESGKMTKDLA 1304 + G T DLA Sbjct: 328 VLAEGHRTADLA 339
>P50180:LEU3_NEILA 3-isopropylmalate dehydrogenase - Neisseria lactamica| Length = 313 Score = 32.7 bits (73), Expect = 6.3 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 6/120 (5%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR FE+ G Y H +D+ +++ + V A N GD+ SD + GSL Sbjct: 201 WREIFEEIGKEYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSL 260 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S + +G+ + E +HG+ G+ N +A+I S + R L+D Sbjct: 261 GMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKANPLATIL--SLAMLLRYSLND 311
>Q9EVI7:LEU3_BUCUN 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp.| Uroleucon sonchi Length = 364 Score = 32.7 bits (73), Expect = 6.3 Identities = 38/158 (24%), Positives = 65/158 (41%), Gaps = 1/158 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + + + E Sbjct: 224 HLYIDNATMQIIKDPNQFDVLLCSNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYE 282 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + S + + + L + K++ + + Sbjct: 283 PAGGSAP------DIEGKNIANPIAQILSVSMLVRY------SMNLKNIADKIDYSVISI 330 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 ++ G T D+A + YL T E D +A+ L Sbjct: 331 LKKGYKTADIA--------HDNNYLKTNEMGDVIADAL 360
>Q4V8C2:ZW10_RAT Centromere/kinetochore protein zw10 homolog - Rattus norvegicus (Rat)| Length = 777 Score = 32.3 bits (72), Expect = 8.2 Identities = 13/30 (43%), Positives = 21/30 (70%) Frame = -2 Query: 1029 QNLEQLDRSAHLHHNSCKPKHSHLHSLGHR 940 +NL++L + A +HHN+C HL +LGH+ Sbjct: 527 ENLQKLPQLAAIHHNNCMYIAHHLLTLGHQ 556
>Q5RFM4:ZW10_PONPY Centromere/kinetochore protein zw10 homolog - Pongo pygmaeus| (Orangutan) Length = 779 Score = 32.3 bits (72), Expect = 8.2 Identities = 13/30 (43%), Positives = 21/30 (70%) Frame = -2 Query: 1029 QNLEQLDRSAHLHHNSCKPKHSHLHSLGHR 940 +NL++L + A +HHN+C HL +LGH+ Sbjct: 529 ENLQKLPQLAAIHHNNCMYIAHHLLTLGHQ 558
>O43264:ZW10_HUMAN Centromere/kinetochore protein zw10 homolog - Homo sapiens (Human)| Length = 779 Score = 32.3 bits (72), Expect = 8.2 Identities = 13/30 (43%), Positives = 21/30 (70%) Frame = -2 Query: 1029 QNLEQLDRSAHLHHNSCKPKHSHLHSLGHR 940 +NL++L + A +HHN+C HL +LGH+ Sbjct: 529 ENLQKLPQLAAIHHNNCMYIAHHLLTLGHQ 558
>Q00939:FOXG1_RAT Forkhead box protein G1 - Rattus norvegicus (Rat)| Length = 480 Score = 32.3 bits (72), Expect = 8.2 Identities = 12/24 (50%), Positives = 15/24 (62%) Frame = -2 Query: 1005 SAHLHHNSCKPKHSHLHSLGHRPP 934 ++H HHNS P+H H H H PP Sbjct: 35 ASHGHHNSHHPQHHHHHHHHHHPP 58
>Q1A1A4:FOXG1_PIPRU Forkhead box protein G1 - Pipistrellus rusticus (Rusty pipistrelle)| Length = 484 Score = 32.3 bits (72), Expect = 8.2 Identities = 12/24 (50%), Positives = 15/24 (62%) Frame = -2 Query: 1005 SAHLHHNSCKPKHSHLHSLGHRPP 934 ++H HHNS P+H H H H PP Sbjct: 35 ASHGHHNSHHPQHHHHHHHHHHPP 58
>Q60987:FOXG1_MOUSE Forkhead box protein G1 - Mus musculus (Mouse)| Length = 481 Score = 32.3 bits (72), Expect = 8.2 Identities = 12/24 (50%), Positives = 15/24 (62%) Frame = -2 Query: 1005 SAHLHHNSCKPKHSHLHSLGHRPP 934 ++H HHNS P+H H H H PP Sbjct: 35 ASHGHHNSHHPQHHHHHHHHHHPP 58
>Q1A1A3:FOXG1_EPOGA Forkhead box protein G1 - Epomophorus gambianus (Gambian epauletted| fruit bat) Length = 485 Score = 32.3 bits (72), Expect = 8.2 Identities = 12/24 (50%), Positives = 15/24 (62%) Frame = -2 Query: 1005 SAHLHHNSCKPKHSHLHSLGHRPP 934 ++H HHNS P+H H H H PP Sbjct: 35 ASHGHHNSHHPQHHHHHHHHHHPP 58
>P51392:YCF26_PORPU Uncharacterized sensor-like histidine kinase ycf26 - Porphyra| purpurea Length = 656 Score = 32.3 bits (72), Expect = 8.2 Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 6/84 (7%) Frame = +3 Query: 1230 LDFTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDK--YLNTMEFIDAVAEELRT-RLS 1400 LD +QKLE + E+G++T+ + ++ + D+ L + + AV + +RT +LS Sbjct: 450 LDDSQKLEFLAIANKETGRLTRLVNDVLDLSRLESDQEYTLQPTDLVSAVEQTIRTYQLS 509 Query: 1401 AKSKL*RYYNDRTSDL---LGSYN 1463 AK K + D +L LG+YN Sbjct: 510 AKDKRIDLHIDIEQNLQCVLGNYN 533
>Q7MP78:LEU3_VIBVY 3-isopropylmalate dehydrogenase - Vibrio vulnificus (strain YJ016)| Length = 363 Score = 32.3 bits (72), Expect = 8.2 Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + + + E Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYE 282 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N +A I S L R L + Q +E A Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQA 330 Query: 1272 VESGKMTKDLA 1304 + +G++T DLA Sbjct: 331 LAAGELTADLA 341
>Q8DEE0:LEU3_VIBVU 3-isopropylmalate dehydrogenase - Vibrio vulnificus| Length = 363 Score = 32.3 bits (72), Expect = 8.2 Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + + + E Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYE 282 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N +A I S L R L + Q +E A Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQA 330 Query: 1272 VESGKMTKDLA 1304 + +G++T DLA Sbjct: 331 LAAGELTADLA 341
>Q9KP82:LEU3_VIBCH 3-isopropylmalate dehydrogenase - Vibrio cholerae| Length = 363 Score = 32.3 bits (72), Expect = 8.2 Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 1/131 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K + V C N GD+ SD A GS+G++ S + + + E Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDILSDECAMITGSMGMLPSASM-NESKFGLYE 282 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N +A I S L R L + D +E A Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAAARD----IENAVSQA 330 Query: 1272 VESGKMTKDLA 1304 + +G++T DLA Sbjct: 331 LAAGELTADLA 341
>Q2YUF1:LEU3_STAAB 3-isopropylmalate dehydrogenase - Staphylococcus aureus (strain| bovine RF122) Length = 348 Score = 32.3 bits (72), Expect = 8.2 Identities = 32/130 (24%), Positives = 54/130 (41%), Gaps = 1/130 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H L+D + + + + V C+N GD+ SD + GSLGL S DG + Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 + +H + + ++A+ F LA L ++ D +LE Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNM 319 Query: 1272 VESGKMTKDL 1301 +E+G+ T DL Sbjct: 320 IENGQTTADL 329
>Q6ND82:LEU3_RHOPA 3-isopropylmalate dehydrogenase - Rhodopseudomonas palustris| Length = 370 Score = 32.3 bits (72), Expect = 8.2 Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 1/136 (0%) Frame = +3 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSV-LVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNS 1160 N GD+ SD+ A GSLG++ S L D +T + ++ + V H G+ N Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGEVDAKTGKRKSMYEPV--HGSAPDIAGKGMANP 303 Query: 1161 IASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDLALLIHGPTVSRDK 1340 +A + S G+A R LD + KL+ A + G T D+ G TV Sbjct: 304 VAMLA--SFGMALRYSLD----MGALADKLDEAIAAVLAKGLRTADIK--SEGTTV---- 351 Query: 1341 YLNTMEFIDAVAEELR 1388 ++T + +A+ EL+ Sbjct: 352 -ISTSQMGEAIVTELQ 366
>Q31B91:LEU3_PROM9 3-isopropylmalate dehydrogenase - Prochlorococcus marinus (strain MIT| 9312) Length = 357 Score = 32.3 bits (72), Expect = 8.2 Identities = 46/197 (23%), Positives = 81/197 (41%), Gaps = 1/197 (0%) Frame = +3 Query: 717 MYNTDESIRAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQQNYETNWRCRFED 896 +Y++ E I E ++ +A Q+ + K+ +L ++ Q +T +D Sbjct: 163 VYDSAE-IERITEIAIKIANQRNKKICSVDKSNVL--------EVSQLWRDTVLNITLKD 213 Query: 897 AGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDG 1073 I + +D+ ++ + V N GD+ SDL A GS+G++ S + +G Sbjct: 214 KNISLSNMYVDNAAMQLVRDPSQFDVILTSNLFGDILSDLAAMLTGSIGMLPSASLNNNG 273 Query: 1074 RTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLE 1253 V E HG+ G+ N IA + + S L K+ N+ + + LE Sbjct: 274 PGV-FEPVHGSAP------DIAGKNIANPIAMLLSASMML----KIGLNEE--EAAKNLE 320 Query: 1254 AACVGTVESGKMTKDLA 1304 A + G T DLA Sbjct: 321 TAVDKVLAEGFRTADLA 337
>Q28W67:LEU3_JANSC 3-isopropylmalate dehydrogenase - Jannaschia sp. (strain CCS1)| Length = 366 Score = 32.3 bits (72), Expect = 8.2 Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 5/111 (4%) Frame = +3 Query: 984 NYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAEAAHGTVTRHYR-VHQKG----GET 1148 N GD+ SD A GSLG++ S ++ A A+G Y VH G+ Sbjct: 245 NLFGDILSDCAAMLTGSLGMLPSA-------SLGAPMANGRPKAMYEPVHGSAPDITGQG 297 Query: 1149 STNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGTVESGKMTKDL 1301 N IA I +++ L + L D +LE A + G T DL Sbjct: 298 KANPIACILSFAMALRYSFDLGDE------ATRLEGAVESVLADGARTADL 342
>P48572:LEU3_BUCRP 3-isopropylmalate dehydrogenase - Buchnera aphidicola subsp.| Rhopalosiphum padi Length = 363 Score = 32.3 bits (72), Expect = 8.2 Identities = 37/158 (23%), Positives = 65/158 (41%), Gaps = 1/158 (0%) Frame = +3 Query: 915 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTVEAE 1091 H ID+ +K+ + V C N GD+ SD A GS+G++ S + + E Sbjct: 223 HLYIDNACMQIIKNPSQFDVLLCSNIFGDIISDECAMITGSIGMLPSASL-NSKKFGLYE 281 Query: 1092 AAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDDNKRLLDFTQKLEAACVGT 1271 A G+ G+ N IA I + S + H L+ + K++++ Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSLSMLIRHSMNLN------EIADKIDSSVYRA 329 Query: 1272 VESGKMTKDLALLIHGPTVSRDKYLNTMEFIDAVAEEL 1385 +++G T D++ Y+ T E D +A+ L Sbjct: 330 LKAGYRTLDIS--------DGKNYIKTNEMGDIIAKFL 359
>Q73B99:LEU3_BACC1 3-isopropylmalate dehydrogenase - Bacillus cereus (strain ATCC 10987)| Length = 354 Score = 32.3 bits (72), Expect = 8.2 Identities = 35/148 (23%), Positives = 58/148 (39%), Gaps = 6/148 (4%) Frame = +3 Query: 876 WRCRFEDAGIWY-----EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDLIAQGFGSL 1037 WR E+ + Y EH L+D +++ G + V +N GD+ SD + GSL Sbjct: 193 WRTVTEEVALRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSL 252 Query: 1038 GLMTSVLVCPDGRTVEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSTGLAHRAKLDD 1217 G++ S G ++ E HG+ ++ S+A + S GL Sbjct: 253 GMLPSASHAEKGPSL-YEPIHGSAPDIAGKNKANPIAMMRSVAMMLGQSFGLTREG---- 307 Query: 1218 NKRLLDFTQKLEAACVGTVESGKMTKDL 1301 +E A ++ GK T D+ Sbjct: 308 --------CAIEEAISAVLKLGKCTADI 327
>Q9JLL0:CRIM1_MOUSE Cysteine-rich motor neuron 1 protein precursor - Mus musculus (Mouse)| Length = 1037 Score = 32.3 bits (72), Expect = 8.2 Identities = 31/153 (20%), Positives = 53/153 (34%), Gaps = 27/153 (17%) Frame = -3 Query: 1445 VTCPIVVVPS*L*FCGQSCP-----------QLLSNRINELHGVQILITTNSWPMDEKS* 1299 +TCP+ + GQ CP +L + I G + + +W +D + Sbjct: 641 ITCPVPACGNPTIRSGQCCPSCTDDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQ 700 Query: 1298 VLCHLSRFHCPHTSSFKFLCEIQQSFVVIQLCPMC*SSRP-------------CKD*RNA 1158 CH R C LC+ S CP C P C++ Sbjct: 701 CTCHSGRVLCETEVCPPLLCQ-NPSRTQDSCCPQCTDDPPQPSTSHNESVPSYCRNDEGD 759 Query: 1157 VCASFASFLVDSVMSCDC---TVCSFSFNCSTI 1068 + + S+ D+ SC C + +S +C ++ Sbjct: 760 IFLAAESWKPDACTSCVCVDSAISCYSESCPSV 792 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 368,504,377 Number of extensions: 7969733 Number of successful extensions: 19288 Number of sequences better than 10.0: 157 Number of HSP's gapped: 19201 Number of HSP's successfully gapped: 157 Length of query: 715 Length of database: 100,686,439 Length adjustment: 121 Effective length of query: 594 Effective length of database: 67,496,744 Effective search space: 40093065936 Effective search space used: 40093065936 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
