ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf60d24 |
|---|---|
| Clone Library Name | barley_pub |
>Q6X4A2:CIPK1_ORYSJ CIPK-like protein 1 - Oryza sativa subsp. japonica (Rice)| Length = 449 Score = 587 bits (1514), Expect = e-167 Identities = 281/426 (65%), Positives = 356/426 (83%), Gaps = 1/426 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YELGRT+GEGTFAKV+FA+N E E VAIKILDK+KV KH+++ QI+REI TMKL++HPN Sbjct: 20 YELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHPN 79 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+R++EVM S+ +I+IV+E VTGGELF+ IA+ GRLKE++ARKYFQQLINAVDYCHSRGV Sbjct: 80 VVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRGV 139 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 YHRDLK ENLLLDA+G LKVSDFGLSAL++QV+ DGLLHTTCGTPNYVAPEVI ++GYDG Sbjct: 140 YHRDLKLENLLLDASGNLKVSDFGLSALTEQVKADGLLHTTCGTPNYVAPEVIEDRGYDG 199 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A AD+WSCGVIL+VL+AG+LPFED N++ALYKKI +A F+CPSWFST AKKLI +ILDPN Sbjct: 200 AAADIWSCGVILYVLLAGFLPFEDDNIIALYKKISEAQFTCPSWFSTGAKKLITRILDPN 259 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRF-ETAEVNLDDINSIFNESGDPAQLVVERREERPAV 1351 P TRITI++++ + WFKKGY+PP F E E + DD+++ F +S D + V E E++P Sbjct: 260 PTTRITISQILEDPWFKKGYKPPVFDEKYETSFDDVDAAFGDSED--RHVKEETEDQPTS 317 Query: 1352 MNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAAAGPMGFNVQKRN 1531 MNAFELIS +Q LNL LFE + + KRETRF S+ P EI++KIE AA P+GF++QK+N Sbjct: 318 MNAFELISLNQALNLDNLFEAKKE-YKRETRFTSQCPPKEIITKIEEAAKPLGFDIQKKN 376 Query: 1532 YKLKLQGENPGRKGQLAIATEVFEVTPSLYMVELRKSNGDTLEFHKFYHSISNGLKDVMW 1711 YK++++ GRKG L +ATEVF+V PSL++VEL+K+ GDTLEF KFY ++S LKDV+W Sbjct: 377 YKMRMENLKAGRKGNLNVATEVFQVAPSLHVVELKKAKGDTLEFQKFYRTLSTQLKDVVW 436 Query: 1712 KPEGSI 1729 K +G + Sbjct: 437 KCDGEV 442
>Q9LDI3:CPK24_ARATH CBL-interacting serine/threonine-protein kinase 24 - Arabidopsis| thaliana (Mouse-ear cress) Length = 446 Score = 523 bits (1346), Expect = e-147 Identities = 254/434 (58%), Positives = 334/434 (76%), Gaps = 2/434 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+GRT+GEGTFAKVKFARN +TG+NVAIKI+ K +LK++M+ QIKREIS MK++RHPN Sbjct: 11 YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPN 70 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+YEV+AS +KIYIV+E VTGGELFD+I +GRL+E ++RKYFQQL++AV +CH +GV Sbjct: 71 IVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGV 130 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 YHRDLKPENLLLD NG LKVSDFGLSAL Q+ E LL TTCGTPNYVAPEV++ +GYDG Sbjct: 131 YHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVE--LLRTTCGTPNYVAPEVLSGQGYDG 188 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + AD+WSCGVILFV++AGYLPF +++L LY+KI A+FSCP WFS K LI +ILDPN Sbjct: 189 SAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPN 248 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRF-ETAEVNLDDINSIFNE-SGDPAQLVVERREERPA 1348 P TRI I + + WF+ Y P R E EVNLDDI ++F+ G VER +E P Sbjct: 249 PKTRIQIQGIKKDPWFRLNYVPIRAREEEEVNLDDIRAVFDGIEGSYVAENVERNDEGPL 308 Query: 1349 VMNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAAAGPMGFNVQKR 1528 +MNAFE+I+ SQGLNL LF+++ D VKR+TRF SR +EI++ IEA A MGF R Sbjct: 309 MMNAFEMITLSQGLNLSALFDRRQDFVKRQTRFVSRREPSEIIANIEAVANSMGFKSHTR 368 Query: 1529 NYKLKLQGENPGRKGQLAIATEVFEVTPSLYMVELRKSNGDTLEFHKFYHSISNGLKDVM 1708 N+K +L+G + + GQLA+ E++EV PSL+MV++RK+ G+TLE+HKFY + + L++++ Sbjct: 369 NFKTRLEGLSSIKAGQLAVVIEIYEVAPSLFMVDVRKAAGETLEYHKFYKKLCSKLENII 428 Query: 1709 WKPEGSIAEGDETR 1750 W+ I + + R Sbjct: 429 WRATEGIPKSEILR 442
>P92937:CPK15_ARATH CBL-interacting serine/threonine-protein kinase 15 - Arabidopsis| thaliana (Mouse-ear cress) Length = 421 Score = 431 bits (1108), Expect = e-120 Identities = 222/408 (54%), Positives = 294/408 (72%), Gaps = 3/408 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+G+ LG+GTFAKV AR+++TG++VAIK++DK+++LK M QIKREIS M+L+RHPN Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRHPN 71 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ ++EVMA+++KIY VME V GGELF+K+ S G+L+ED ARKYFQQL+ AVD+CHSRGV Sbjct: 72 IVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYFQQLVRAVDFCHSRGV 130 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD +G LK+SDFGLSALS R+DGLLHTTCGTP YVAPEVI+ GYDG Sbjct: 131 CHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDG 190 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 KAD+WSCGVILFVL+AGYLPF DSNLM LYKKI KA+ P+W + AK+L+K+ILDPN Sbjct: 191 FKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGAKRLLKRILDPN 250 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFETAEVNLD-DINSIFNESGDPAQLVVERREERPAV 1351 PNTR++ +++ + WF+KG Q E+ E + D + N S E+ ++R Sbjct: 251 PNTRVSTEKIMKSSWFRKGLQEEVKESVEEETEVDAEAEGNAS-------AEKEKKRCIN 303 Query: 1352 MNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAAAGPMGFNVQKR- 1528 +NAFE+IS S G +L LFEK + K E RF S A+EI K+ + V+K+ Sbjct: 304 LNAFEIISLSTGFDLSGLFEKGEE--KEEMRFTSNREASEITEKLVEIGKDLKMKVRKKE 361 Query: 1529 -NYKLKLQGENPGRKGQLAIATEVFEVTPSLYMVELRKSNGDTLEFHK 1669 +++K+ E + EVFE+ PS +MV L+KS GDT E+ + Sbjct: 362 HEWRVKMSAE------ATVVEAEVFEIAPSYHMVVLKKSGGDTAEYKR 403
>Q8RWC9:CIPK1_ARATH CBL-interacting serine/threonine-protein kinase 1 - Arabidopsis| thaliana (Mouse-ear cress) Length = 444 Score = 431 bits (1108), Expect = e-120 Identities = 220/422 (52%), Positives = 296/422 (70%), Gaps = 5/422 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YELGRTLGEG F KVKFA++ +G + A+KI+DK ++ QIKREI T+K+++HP+ Sbjct: 20 YELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHPH 79 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R++EV+AS+TKI +VMELVTGGELFD+I S G+L E D RK FQQLI+ + YCHS+GV Sbjct: 80 IVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKGV 139 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +HRDLK EN+LLDA G +K++DFGLSAL Q R+DGLLHTTCG+PNYVAPEV+ N+GYDG Sbjct: 140 FHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYDG 199 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A +D+WSCGVIL+V++ G LPF+D NL LY+KI K D P W S A+ +IK++LDPN Sbjct: 200 AASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGARTMIKRMLDPN 259 Query: 1175 PNTRITIAEVINNEWFKKGY---QPPRFETAEVNLDDINSIFNESGDPAQLVVERREERP 1345 P TRIT+ + +EWFK Y P + EV+ DD E G + + P Sbjct: 260 PVTRITVVGIKASEWFKLEYIPSIPDDDDEEEVDTDDDAFSIQELGSEE----GKGSDSP 315 Query: 1346 AVMNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAAAGPMGFNVQK 1525 ++NAF+LI S L+L FE++ S +R RF S A ++L KIE A MGF+VQK Sbjct: 316 TIINAFQLIGMSSFLDLSGFFEQENVS-ERRIRFTSNSSAKDLLEKIETAVTEMGFSVQK 374 Query: 1526 RNYKLKLQGENPGRKGQ--LAIATEVFEVTPSLYMVELRKSNGDTLEFHKFYHSISNGLK 1699 ++ KL+++ E +KGQ L++ EVFE+ PSL +VELRKS GD+ + + Y + LK Sbjct: 375 KHAKLRVKQEERNQKGQVGLSVTAEVFEIKPSLNVVELRKSYGDSCLYRQLYERL---LK 431 Query: 1700 DV 1705 DV Sbjct: 432 DV 433
>O22932:CPK11_ARATH CBL-interacting serine/threonine-protein kinase 11 - Arabidopsis| thaliana (Mouse-ear cress) Length = 435 Score = 376 bits (966), Expect = e-103 Identities = 195/403 (48%), Positives = 268/403 (66%), Gaps = 4/403 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQ-IKREISTMKLIRHP 631 YELG+ LG G FAKV AR+ TG++VA+KIL+K K+L + +A IKREIS M+ + HP Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHP 80 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 N+++++EVMA+++KI+ ME V GGELF+KI+ GRL ED +R+YFQQLI+AV YCH+RG Sbjct: 81 NIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARG 140 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 991 VYHRDLKPENLL+D NG LKVSDFGLSAL+ Q+R DGLLHT CGTP YVAPE+++ KGY+ Sbjct: 141 VYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE 200 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 GAK D+WSCG++LFVL+AGYLPF D N+M +YKKIYK ++ P W S K+ + ++LD Sbjct: 201 GAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDI 260 Query: 1172 NPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDPAQLVVERREERPAV 1351 NP TRITI E++ + WF +G F+ + + D+I VE E Sbjct: 261 NPETRITIDEILKDPWFVRG----GFKQIKFHDDEIE----------DQKVESSLEAVKS 306 Query: 1352 MNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAAAGPMGFNVQKR- 1528 +NAF+LIS S GL+L LF ++S RF S + ++E A ++K+ Sbjct: 307 LNAFDLISYSSGLDLSGLFAGCSNSSGESERFLSEKSPEMLAEEVEGFAREENLRMKKKK 366 Query: 1529 --NYKLKLQGENPGRKGQLAIATEVFEVTPSLYMVELRKSNGD 1651 Y +++G+N G+ I + + L +VE R+ GD Sbjct: 367 EEEYGFEMEGQN----GKFGIGICISRLNDLLVVVEARRRGGD 405
>P92958:KIN11_ARATH SNF1-related protein kinase catalytic subunit alpha KIN11 -| Arabidopsis thaliana (Mouse-ear cress) Length = 512 Score = 272 bits (696), Expect = 3e-72 Identities = 151/365 (41%), Positives = 221/365 (60%), Gaps = 13/365 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+LG+TLG G+F KVK A +V TG VAIKIL++ K+ +M +++REI ++L HP+ Sbjct: 20 YKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 79 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR YEV+ + + IY+VME V GELFD I +GRL+ED+AR +FQQ+I+ V+YCH V Sbjct: 80 IIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMV 139 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD+ +K++DFGLS + +R+ L T+CG+PNY APEVI+ K Y G Sbjct: 140 VHRDLKPENLLLDSRCNIKIADFGLSNV---MRDGHFLKTSCGSPNYAAPEVISGKLYAG 196 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WSCGVIL+ L+ G LPF+D N+ L+KKI ++ PS S+ A+ LI ++L + Sbjct: 197 PEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVD 256 Query: 1175 PNTRITIAEVINNEWFKK------GYQPPRF--ETAEVNLDDINSIFNESGDPAQLV--V 1324 P RITI E+ + WF+ PP + ++N + + + N D Q++ + Sbjct: 257 PVKRITIPEIRQHRWFQTHLPRYLAVSPPDTVEQAKKINEEIVQEVVNMGFDRNQVLESL 316 Query: 1325 ERREERPAVMNAFELISTSQGLNLGTL---FEKQTDSVKRETRFASRLPANEILSKIEAA 1495 R + A + + L+ + G L F++ TDS R EA Sbjct: 317 RNRTQNDATVTYYLLLDNRFRVPSGYLESEFQETTDSGSNPMRTP------------EAG 364 Query: 1496 AGPMG 1510 A P+G Sbjct: 365 ASPVG 369
>Q38997:KIN10_ARATH SNF1-related protein kinase catalytic subunit alpha KIN10 -| Arabidopsis thaliana (Mouse-ear cress) Length = 535 Score = 267 bits (682), Expect = 1e-70 Identities = 129/257 (50%), Positives = 182/257 (70%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+LGRTLG G+F +VK A + TG VAIKIL++ K+ +M +++REI ++L HP+ Sbjct: 42 YKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 101 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR+YEV+ + T IY+VME V GELFD I +GRL+ED+AR +FQQ+I+ V+YCH V Sbjct: 102 IIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMV 161 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD+ +K++DFGLS + +R+ L T+CG+PNY APEVI+ K Y G Sbjct: 162 VHRDLKPENLLLDSKCNVKIADFGLSNI---MRDGHFLKTSCGSPNYAAPEVISGKLYAG 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WSCGVIL+ L+ G LPF+D N+ L+KKI ++ PS S A+ LI ++L + Sbjct: 219 PEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVD 278 Query: 1175 PNTRITIAEVINNEWFK 1225 P R+TI E+ + WF+ Sbjct: 279 PMKRVTIPEIRQHPWFQ 295
>O94168:SNF1_CANTR Carbon catabolite derepressing protein kinase - Candida tropicalis| (Yeast) Length = 619 Score = 262 bits (669), Expect = 4e-69 Identities = 128/281 (45%), Positives = 200/281 (71%), Gaps = 7/281 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ +TLGEG+F KVK A++V TG+ VA+KI+++ + K M +++REIS ++L+RHP+ Sbjct: 52 YQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPH 111 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+ S+ +I +V+E G ELFD I RG++ ED+AR++FQQ+I AV+YCH + Sbjct: 112 IIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHKI 170 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD +K++DFGLS + + + L T+CG+PNY APEVI+ K Y G Sbjct: 171 VHRDLKPENLLLDDQLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVISGKLYAG 227 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+V++ G LPF+D + AL+KKI ++ P++ S AK L+ ++L N Sbjct: 228 PEVDVWSSGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSPGAKHLLTRMLVVN 287 Query: 1175 PNTRITIAEVINNEWFKKGYQ----PP---RFETAEVNLDD 1276 P RITI E++ +EWFK+ PP + +T+++++D+ Sbjct: 288 PLNRITIHEIMEDEWFKQDMPDYLLPPDLSKIKTSKIDIDE 328
>Q5RD00:AAPK2_PONPY 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Pongo| pygmaeus (Orangutan) Length = 552 Score = 258 bits (660), Expect = 5e-68 Identities = 129/282 (45%), Positives = 187/282 (66%), Gaps = 4/282 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG TLG GTF KVK + TG VA+KIL++ K+ ++ +IKREI +KL RHP+ Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+++ T ++VME V+GGELFD I GR++E +AR+ FQQ+++AVDYCH V Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDG-LLHTTCGTPNYVAPEVINNKGYD 991 HRDLKPEN+LLDA+ K++DFGLS + DG L T+CG+PNY APEVI+ + Y Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGLS----NIMSDGEFLRTSCGSPNYAAPEVISGRLYA 191 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 G + D+WSCGVIL+ L+ G LPF+D ++ L+KKI F P + + S L+ +L Sbjct: 192 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQV 251 Query: 1172 NPNTRITIAEVINNEWFKK---GYQPPRFETAEVNLDDINSI 1288 +P R TI ++ +EWFK+ Y P + + N+ D ++ Sbjct: 252 DPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAV 293
>P54646:AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Homo| sapiens (Human) Length = 552 Score = 258 bits (658), Expect = 8e-68 Identities = 127/281 (45%), Positives = 186/281 (66%), Gaps = 3/281 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG TLG GTF KVK + TG VA+KIL++ K+ ++ +IKREI +KL RHP+ Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+++ T ++VME V+GGELFD I GR++E +AR+ FQQ+++AVDYCH V Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPEN+LLDA+ K++DFG LS + + L T+CG+PNY APEVI+ + Y G Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WSCGVIL+ L+ G LPF+D ++ L+KKI F P + + S L+ +L + Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252 Query: 1175 PNTRITIAEVINNEWFKK---GYQPPRFETAEVNLDDINSI 1288 P R TI ++ +EWFK+ Y P + + N+ D ++ Sbjct: 253 PLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAV 293
>Q00372:SNF1_CANGA Carbon catabolite derepressing protein kinase - Candida glabrata| (Yeast) (Torulopsis glabrata) Length = 612 Score = 257 bits (657), Expect = 1e-67 Identities = 137/336 (40%), Positives = 210/336 (62%), Gaps = 24/336 (7%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ +TLGEG+F KVK A +V TG+ VA+KI++K + K M +I+REIS ++L+RHP+ Sbjct: 39 YQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 98 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+ S+ +I +V+E G ELFD I R ++ E +AR++FQQ+I+AV+YCH + Sbjct: 99 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVEYCHRHKI 157 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD + +K++DFGLS + + + L T+CG+PNY APEVI+ K Y G Sbjct: 158 VHRDLKPENLLLDEHLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVISGKLYAG 214 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WSCGVIL+V++ LPF+D ++ L+K I ++ P + S A LIK++L N Sbjct: 215 PEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGASDLIKRMLIVN 274 Query: 1175 PNTRITIAEVINNEWFKKGY----------QPPRFETAEVNLDDINSIFNE--------- 1297 P RI+I E++ +EWFK Q +F N +++ I +E Sbjct: 275 PLNRISIHEIMQDEWFKVDLAEYLVPQDLKQQEQFNKKSGNEENVEEIDDEMVVTLSKTM 334 Query: 1298 --SGDPAQLVVERREERPA---VMNAFELISTSQGL 1390 D +E E+ PA + NA+ LI ++ L Sbjct: 335 GYDKDEIYEALESSEDTPAYNEIRNAYILIKDNKSL 370
>Q28948:AAPK2_PIG 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Sus| scrofa (Pig) Length = 552 Score = 257 bits (657), Expect = 1e-67 Identities = 127/281 (45%), Positives = 185/281 (65%), Gaps = 3/281 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG TLG GTF KVK + TG VA+KIL++ K+ ++ +IKREI +KL RHP+ Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+++ T ++VME V+GGELFD I GR++E +AR+ FQQ+++AVDYCH V Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPEN+LLDA K++DFG LS + + L T+CG+PNY APEVI+ + Y G Sbjct: 136 VHRDLKPENVLLDAQMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WSCGVIL+ L+ G LPF+D ++ L+KKI F P + + S L+ +L + Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252 Query: 1175 PNTRITIAEVINNEWFKK---GYQPPRFETAEVNLDDINSI 1288 P R TI ++ +EWFK+ Y P + + N+ D ++ Sbjct: 253 PLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAV 293
>Q8BRK8:AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Mus| musculus (Mouse) Length = 552 Score = 257 bits (657), Expect = 1e-67 Identities = 129/282 (45%), Positives = 185/282 (65%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG TLG GTF KVK + TG VA+KIL++ K+ ++ +IKREI +KL RHP+ Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+++ T ++VME V+GGELFD I GR++E +AR+ FQQ+++AVDYCH V Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMV 135 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPEN+LLDA K++DFG LS + + L T+CG+PNY APEVI+ + Y G Sbjct: 136 VHRDLKPENVLLDAQMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WSCGVIL+ L+ G LPF+D ++ L+KKI F P + + S L+ +L + Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPDYLNRSVATLLMHMLQVD 252 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNES 1300 P R TI ++ +EWFK+ P + E D N I +E+ Sbjct: 253 PLKRATIKDIREHEWFKQDL--PSYLFPEDPSYDANVIVDEA 292
>Q09137:AAPK2_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Rattus| norvegicus (Rat) Length = 552 Score = 257 bits (656), Expect = 1e-67 Identities = 127/281 (45%), Positives = 185/281 (65%), Gaps = 3/281 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG TLG GTF KVK + TG VA+KIL++ K+ ++ +IKREI +KL RHP+ Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+++ T ++VME V+GGELFD I GR++E +AR+ FQQ+++AVDYCH V Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMV 135 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPEN+LLDA K++DFG LS + + L T+CG+PNY APEVI+ + Y G Sbjct: 136 VHRDLKPENVLLDAQMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WSCGVIL+ L+ G LPF+D ++ L+KKI F P + + S L+ +L + Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMHMLQVD 252 Query: 1175 PNTRITIAEVINNEWFKK---GYQPPRFETAEVNLDDINSI 1288 P R TI ++ +EWFK+ Y P + + N+ D ++ Sbjct: 253 PLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAV 293
>P52497:SNF1_CANAL Carbon catabolite derepressing protein kinase - Candida albicans| (Yeast) Length = 620 Score = 254 bits (648), Expect = 1e-66 Identities = 122/259 (47%), Positives = 189/259 (72%), Gaps = 1/259 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ +TLGEG+F KVK A+++ TG+ VA+KI+++ + K M +++REIS ++L+RHP+ Sbjct: 53 YQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPH 112 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+ S+ +I +V+E G ELFD I RG++ ED+AR++FQQ+I AV+YCH + Sbjct: 113 IIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHKI 171 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYV-APEVINNKGYD 991 HRDLKPENLLLD +K++DFGLS + + + L T+CG+PNY+ APEVI+ K Y Sbjct: 172 VHRDLKPENLLLDDQLNVKIADFGLSNI---MTDGNFLKTSCGSPNYMPAPEVISGKLYA 228 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 G + D+WS GVIL+V++ G LPF+D + AL+KKI ++ P++ S AK L+ ++L Sbjct: 229 GPEVDVWSAGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSAGAKHLLTRMLVV 288 Query: 1172 NPNTRITIAEVINNEWFKK 1228 NP RITI E++ ++WFK+ Sbjct: 289 NPLNRITIHEIMEDDWFKQ 307
>Q95ZQ4:AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-2 -| Caenorhabditis elegans Length = 626 Score = 253 bits (646), Expect = 2e-66 Identities = 126/281 (44%), Positives = 184/281 (65%), Gaps = 3/281 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L TLG GTF KVK + T VA+KIL++ K+ ++ +I+REI + L RHP+ Sbjct: 87 YILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPH 146 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR+Y+V+++ + I+++ME V+GGELFD I GRLK +AR++FQQ+I+ VDYCH V Sbjct: 147 IIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMV 206 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD +K++DFGLS + + + L T+CG+PNY APEVI+ K Y G Sbjct: 207 VHRDLKPENLLLDEQNNVKIADFGLSNI---MTDGDFLRTSCGSPNYAAPEVISGKLYAG 263 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WSCGVIL+ L+ G LPF+D ++ +L++KI F P + L+ +L + Sbjct: 264 PEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHMLCVD 323 Query: 1175 PNTRITIAEVINNEWFKK---GYQPPRFETAEVNLDDINSI 1288 P R TI +VI +EWF+K Y P +E ++ DI ++ Sbjct: 324 PMKRATIKDVIAHEWFQKDLPNYLFPPINESEASIVDIEAV 364
>P54645:AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Rattus| norvegicus (Rat) Length = 548 Score = 253 bits (646), Expect = 2e-66 Identities = 121/258 (46%), Positives = 177/258 (68%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG TLG GTF KVK ++ TG VA+KIL++ K+ ++ +I+REI +KL RHP+ Sbjct: 16 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 75 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+++ + I++VME V+GGELFD I GRL E ++R+ FQQ+++ VDYCH V Sbjct: 76 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 135 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPEN+LLDA+ K++DFG LS + + L T+CG+PNY APEVI+ + Y G Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L+ G LPF+D ++ L+KKI F P + + S L+K +L + Sbjct: 193 PEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVD 252 Query: 1175 PNTRITIAEVINNEWFKK 1228 P R TI ++ +EWFK+ Sbjct: 253 PMKRATIKDIREHEWFKQ 270
>Q5RDH5:AAPK1_PONPY 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Pongo| pygmaeus (Orangutan) Length = 550 Score = 253 bits (646), Expect = 2e-66 Identities = 121/258 (46%), Positives = 177/258 (68%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG TLG GTF KVK ++ TG VA+KIL++ K+ ++ +I+REI +KL RHP+ Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 77 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+++ + I++VME V+GGELFD I GRL E ++R+ FQQ+++ VDYCH V Sbjct: 78 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 137 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPEN+LLDA+ K++DFG LS + + L T+CG+PNY APEVI+ + Y G Sbjct: 138 VHRDLKPENVLLDAHMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 194 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L+ G LPF+D ++ L+KKI F P + + S L+K +L + Sbjct: 195 PEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVD 254 Query: 1175 PNTRITIAEVINNEWFKK 1228 P R TI ++ +EWFK+ Sbjct: 255 PMKRATIKDIREHEWFKQ 272
>Q13131:AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Homo| sapiens (Human) Length = 550 Score = 253 bits (646), Expect = 2e-66 Identities = 121/258 (46%), Positives = 177/258 (68%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG TLG GTF KVK ++ TG VA+KIL++ K+ ++ +I+REI +KL RHP+ Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 77 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+++ + I++VME V+GGELFD I GRL E ++R+ FQQ+++ VDYCH V Sbjct: 78 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 137 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPEN+LLDA+ K++DFG LS + + L T+CG+PNY APEVI+ + Y G Sbjct: 138 VHRDLKPENVLLDAHMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 194 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L+ G LPF+D ++ L+KKI F P + + S L+K +L + Sbjct: 195 PEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVD 254 Query: 1175 PNTRITIAEVINNEWFKK 1228 P R TI ++ +EWFK+ Sbjct: 255 PMKRATIKDIREHEWFKQ 272
>P06782:SNF1_YEAST Carbon catabolite derepressing protein kinase - Saccharomyces| cerevisiae (Baker's yeast) Length = 633 Score = 252 bits (643), Expect = 4e-66 Identities = 120/257 (46%), Positives = 183/257 (71%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ +TLGEG+F KVK A + TG+ VA+KI++K + K M +I+REIS ++L+RHP+ Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 114 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+ S+ +I +V+E G ELFD I R ++ E +AR++FQQ+I+AV+YCH + Sbjct: 115 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKI 173 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD + +K++DFGLS + + + L T+CG+PNY APEVI+ K Y G Sbjct: 174 VHRDLKPENLLLDEHLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVISGKLYAG 230 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WSCGVIL+V++ LPF+D ++ L+K I ++ P + S A LIK++L N Sbjct: 231 PEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVN 290 Query: 1175 PNTRITIAEVINNEWFK 1225 P RI+I E++ ++WFK Sbjct: 291 PLNRISIHEIMQDDWFK 307
>Q5EG47:AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Mus| musculus (Mouse) Length = 548 Score = 251 bits (641), Expect = 8e-66 Identities = 120/258 (46%), Positives = 176/258 (68%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG TLG GTF KVK ++ TG VA+KIL++ K+ ++ +I+REI +KL RHP+ Sbjct: 16 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 75 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+++ + I++VME V+GGELFD I GRL E ++R+ FQQ+++ VDYCH V Sbjct: 76 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 135 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPEN+LLDA+ K++DFG LS + + L T+CG+PNY APEVI+ + Y G Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L+ G LPF+D ++ L+KKI F P + + S L+K +L + Sbjct: 193 PEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVD 252 Query: 1175 PNTRITIAEVINNEWFKK 1228 P R I ++ +EWFK+ Sbjct: 253 PMKRAAIKDIREHEWFKQ 270
>O74536:SNF1_SCHPO SNF1-like protein kinase ssp2 - Schizosaccharomyces pombe (Fission| yeast) Length = 576 Score = 246 bits (629), Expect = 2e-64 Identities = 128/317 (40%), Positives = 197/317 (62%), Gaps = 7/317 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y + TLGEG+F KVK A + +T + VA+K + + + K M +++REIS +KL+RHP+ Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPH 93 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+V+ + T I +V+E GGELFD I + R+ ED+ R++FQQ+I A++YCH + Sbjct: 94 IIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKI 152 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD N +K++DFGLS + + + L T+CG+PNY APEVIN K Y G Sbjct: 153 VHRDLKPENLLLDDNLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVINGKLYAG 209 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WSCG++L+V++ G LPF+D + L+KK+ + P + S A+ LI++++ + Sbjct: 210 PEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMIVAD 269 Query: 1175 PNTRITIAEVINNEWFK---KGYQPPRFETAEVNLDD--INSIFNESGDPAQLVVE--RR 1333 P RITI E+ + WF Y P E D ++ + G +VE R Sbjct: 270 PMQRITIQEIRRDPWFNVNLPDYLRPMEEVQGSYADSRIVSKLGEAMGFSEDYIVEALRS 329 Query: 1334 EERPAVMNAFELISTSQ 1384 +E V A+ L+ +Q Sbjct: 330 DENNEVKEAYNLLHENQ 346
>Q61846:MELK_MOUSE Maternal embryonic leucine zipper kinase - Mus musculus (Mouse)| Length = 643 Score = 244 bits (624), Expect = 7e-64 Identities = 122/263 (46%), Positives = 178/263 (67%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YEL T+G G FAKVK A +V TGE VAIKI+DK+ + + ++K EI +K +RH + Sbjct: 11 YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSD--LPRVKTEIDALKSLRHQH 68 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 + ++Y V+ ++ KI++V+E GGELFD I S+ RL E++ R F+Q+++AV Y HS+G Sbjct: 69 ICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHSQGY 128 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLL D N LK+ DFGL A + +D L T CG+ Y APE+I K Y G Sbjct: 129 AHRDLKPENLLFDENHKLKLIDFGLCA-KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLG 187 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 ++AD+WS G++L+VLM G+LPF+D N+MALYKKI + + P W S S+ L++++L + Sbjct: 188 SEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSILLLQQMLQVD 247 Query: 1175 PNTRITIAEVINNEWFKKGYQPP 1243 P RI++ ++N+ W + Y P Sbjct: 248 PKKRISMRNLLNHPWVMQDYSCP 270
>Q14680:MELK_HUMAN Maternal embryonic leucine zipper kinase - Homo sapiens (Human)| Length = 651 Score = 242 bits (617), Expect = 5e-63 Identities = 124/277 (44%), Positives = 183/277 (66%), Gaps = 3/277 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YEL T+G G FAKVK A ++ TGE VAIKI+DK+ + + +IK EI +K +RH + Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSD--LPRIKTEIEALKNLRHQH 68 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 + ++Y V+ + KI++V+E GGELFD I S+ RL E++ R F+Q+++AV Y HS+G Sbjct: 69 ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGY 128 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLL D LK+ DFGL A + +D L T CG+ Y APE+I K Y G Sbjct: 129 AHRDLKPENLLFDEYHKLKLIDFGLCA-KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLG 187 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 ++AD+WS G++L+VLM G+LPF+D N+MALYKKI + + P W S S+ L++++L + Sbjct: 188 SEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVD 247 Query: 1175 PNTRITIAEVINNEWFKKGYQPP---RFETAEVNLDD 1276 P RI++ ++N+ W + Y P + + ++LDD Sbjct: 248 PKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDD 284
>Q8TDC3:BRSK1_HUMAN BR serine/threonine-protein kinase 1 - Homo sapiens (Human)| Length = 794 Score = 241 bits (615), Expect = 8e-63 Identities = 109/263 (41%), Positives = 179/263 (68%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +TLG+G VK + TG+ VAIKI++++K L ++ +++REI+ +KLI HP+ Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREK-LSESVLMKVEREIAILKLIEHPH 108 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+++++V ++ +Y+V+E V+GGELFD + +GRL +ARK+F+Q+++A+D+CHS + Sbjct: 109 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 168 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD ++++DFG+++L D LL T+CG+P+Y PEVI + YDG Sbjct: 169 CHRDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIKGEKYDG 225 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 +AD+WSCGVILF L+ G LPF+D NL L +K+ + F P + + L++ +++ Sbjct: 226 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 285 Query: 1175 PNTRITIAEVINNEWFKKGYQPP 1243 P R+++ ++ + W+ G P Sbjct: 286 PEKRLSLEQIQKHPWYLGGKHEP 308
>Q6NSM8:QSK_DANRE Serine/threonine-protein kinase QSK homolog - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 1187 Score = 241 bits (614), Expect = 1e-62 Identities = 118/275 (42%), Positives = 178/275 (64%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+ RT+G+G FA VK A ++ T VAIKI+DK + L + + +I RE+ MK++RHP+ Sbjct: 59 YEMERTIGKGNFAVVKLATHMITKAKVAIKIVDKTQ-LDDENLKKIFREVQIMKMLRHPH 117 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR+Y+VM + IY+V E +GGE+FD + + GR+ E DAR+ F+Q++ AV +CH R + Sbjct: 118 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKDARRKFKQIVAAVYFCHCRSI 177 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLD N +K++DFG S L + + LL T CG+P Y APE+ K YDG Sbjct: 178 VHRDLKAENLLLDHNLNIKIADFGFSNLFSRGQ---LLKTWCGSPPYAAPELFEGKEYDG 234 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K D+WS GV+L+VL+ G LPF+ S L L ++ F P + ST + LI+ +L Sbjct: 235 PKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTDCEYLIRHMLILE 294 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDI 1279 P+ R+++ ++ N+W ++G P F+ V + + Sbjct: 295 PSRRLSMEQICKNKWMRQGDPDPEFDRLIVECEQV 329
>Q5RJI5:BRSK1_MOUSE BR serine/threonine-protein kinase 1 - Mus musculus (Mouse)| Length = 778 Score = 241 bits (614), Expect = 1e-62 Identities = 108/263 (41%), Positives = 179/263 (68%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +TLG+G VK + TG+ VA+KI++++K L ++ +++REI+ +KLI HP+ Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNREK-LSESVLMKVEREIAILKLIEHPH 92 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+++++V ++ +Y+V+E V+GGELFD + +GRL +ARK+F+Q+++A+D+CHS + Sbjct: 93 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 152 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD ++++DFG+++L D LL T+CG+P+Y PEVI + YDG Sbjct: 153 CHRDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIKGEKYDG 209 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 +AD+WSCGVILF L+ G LPF+D NL L +K+ + F P + + L++ +++ Sbjct: 210 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 269 Query: 1175 PNTRITIAEVINNEWFKKGYQPP 1243 P R+++ ++ + W+ G P Sbjct: 270 PEKRLSLEQIQKHPWYLGGKHEP 292
>O08678:MARK1_RAT Serine/threonine-protein kinase MARK1 - Rattus norvegicus (Rat)| Length = 793 Score = 239 bits (611), Expect = 2e-62 Identities = 114/281 (40%), Positives = 182/281 (64%), Gaps = 3/281 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +T+G+G FAKVK AR+V TG VA+KI+DK + L + ++ RE+ MK++ HPN Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 118 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCI 178 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 179 VHRDLKAENLLLDADMNIKIADFG---FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK+L N Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLLVLN 295 Query: 1175 PNTRITIAEVINNEWFKKGYQPPR---FETAEVNLDDINSI 1288 P R ++ +++ + W G++ + E++L+D I Sbjct: 296 PIKRGSLEQIMKDRWMNVGHEEEELKPYSEPELDLNDAKRI 336
>Q8VHJ5:MARK1_MOUSE Serine/threonine-protein kinase MARK1 - Mus musculus (Mouse)| Length = 795 Score = 239 bits (611), Expect = 2e-62 Identities = 114/281 (40%), Positives = 182/281 (64%), Gaps = 3/281 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +T+G+G FAKVK AR+V TG VA+KI+DK + L + ++ RE+ MK++ HPN Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 118 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCI 178 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 179 VHRDLKAENLLLDADMNIKIADFG---FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK+L N Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLLVLN 295 Query: 1175 PNTRITIAEVINNEWFKKGYQPPR---FETAEVNLDDINSI 1288 P R ++ +++ + W G++ + E++L+D I Sbjct: 296 PIKRGSLEQIMKDRWMNVGHEEEELKPYSEPELDLNDAKRI 336
>O08679:MARK2_RAT Serine/threonine-protein kinase MARK2 - Rattus norvegicus (Rat)| Length = 722 Score = 239 bits (610), Expect = 3e-62 Identities = 110/261 (42%), Positives = 175/261 (67%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +T+G+G FAKVK AR++ TG+ VA+KI+DK + L + ++ RE+ MK++ HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ-LNSSSLQKLFREVRIMKVLNHPN 111 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 172 VHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDG 228 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK L N Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILN 288 Query: 1175 PNTRITIAEVINNEWFKKGYQ 1237 P+ R T+ +++ + W G++ Sbjct: 289 PSKRGTLEQIMKDRWMNVGHE 309
>Q7KZI7:MARK2_HUMAN Serine/threonine-protein kinase MARK2 - Homo sapiens (Human)| Length = 788 Score = 239 bits (610), Expect = 3e-62 Identities = 110/261 (42%), Positives = 175/261 (67%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +T+G+G FAKVK AR++ TG+ VA+KI+DK + L + ++ RE+ MK++ HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ-LNSSSLQKLFREVRIMKVLNHPN 111 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 172 VHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDG 228 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK L N Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILN 288 Query: 1175 PNTRITIAEVINNEWFKKGYQ 1237 P+ R T+ +++ + W G++ Sbjct: 289 PSKRGTLEQIMKDRWMNVGHE 309
>Q6P4S6:QSK_MOUSE Serine/threonine-protein kinase QSK - Mus musculus (Mouse)| Length = 1311 Score = 238 bits (608), Expect = 5e-62 Identities = 117/266 (43%), Positives = 173/266 (65%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+ RT+G+G FA VK A ++ T VAIKI+DK + L + + +I RE+ MK++ HP+ Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQ-LDEENLKKIFREVQIMKMLCHPH 66 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR+Y+VM + IY+V E +GGE+FD + + GR+ E +AR+ F+Q++ AV +CH R + Sbjct: 67 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 126 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDAN +K++DFG S L LL T CG+P Y APE+ K YDG Sbjct: 127 VHRDLKAENLLLDANLNIKIADFGFSNL---FTPGQLLKTWCGSPPYAAPELFEGKEYDG 183 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K D+WS GV+L+VL+ G LPF+ S L L ++ F P + ST + LI+ +L + Sbjct: 184 PKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLD 243 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFE 1252 PN R+++ ++ ++W K G P F+ Sbjct: 244 PNKRLSMEQICRHKWMKLGDADPNFD 269
>Q9Y2K2:QSK_HUMAN Serine/threonine-protein kinase QSK - Homo sapiens (Human)| Length = 1263 Score = 238 bits (607), Expect = 7e-62 Identities = 117/266 (43%), Positives = 173/266 (65%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+ RT+G+G FA VK A ++ T VAIKI+DK + L + + +I RE+ MK++ HP+ Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQ-LDEENLKKIFREVQIMKMLCHPH 66 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR+Y+VM + IY+V E +GGE+FD + + GR+ E +AR+ F+Q++ AV +CH R + Sbjct: 67 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 126 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDAN +K++DFG S L LL T CG+P Y APE+ K YDG Sbjct: 127 VHRDLKAENLLLDANLNIKIADFGFSNL---FTPGQLLKTWCGSPPYAAPELFEGKEYDG 183 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K D+WS GV+L+VL+ G LPF+ S L L ++ F P + ST + LI+ +L + Sbjct: 184 PKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLD 243 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFE 1252 PN R+++ ++ ++W K G P F+ Sbjct: 244 PNKRLSMEQICKHKWMKLGDADPNFD 269
>Q8CIP4:MARK4_MOUSE MAP/microtubule affinity-regulating kinase 4 - Mus musculus (Mouse)| Length = 752 Score = 237 bits (605), Expect = 1e-61 Identities = 110/261 (42%), Positives = 171/261 (65%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L RT+G+G FAKVK AR++ TG VAIKI+DK + L + ++ RE+ MK + HPN Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPSSLQKLFREVRIMKGLNHPN 117 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV+ + +Y+VME + GE+FD + S GR+KE +AR F+Q+++AV YCH + + Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDA +K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 178 VHRDLKAENLLLDAEANIKIADFG---FSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDG 234 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + ++++ L N Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLN 294 Query: 1175 PNTRITIAEVINNEWFKKGYQ 1237 P R T+ +++ ++W GY+ Sbjct: 295 PAKRCTLEQIMKDKWINIGYE 315
>Q96L34:MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 - Homo sapiens (Human)| Length = 752 Score = 237 bits (605), Expect = 1e-61 Identities = 110/261 (42%), Positives = 171/261 (65%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L RT+G+G FAKVK AR++ TG VAIKI+DK + L + ++ RE+ MK + HPN Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPSSLQKLFREVRIMKGLNHPN 117 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV+ + +Y+VME + GE+FD + S GR+KE +AR F+Q+++AV YCH + + Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDA +K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 178 VHRDLKAENLLLDAEANIKIADFG---FSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDG 234 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + ++++ L N Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLN 294 Query: 1175 PNTRITIAEVINNEWFKKGYQ 1237 P R T+ +++ ++W GY+ Sbjct: 295 PAKRCTLEQIMKDKWINIGYE 315
>Q8VHF0:MARK3_RAT MAP/microtubule affinity-regulating kinase 3 - Rattus norvegicus| (Rat) Length = 797 Score = 237 bits (605), Expect = 1e-61 Identities = 112/277 (40%), Positives = 179/277 (64%), Gaps = 3/277 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +T+G+G FAKVK AR++ TG VAIKI+DK + L + ++ RE+ MK++ HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 114 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV+ + +Y++ME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 174 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 175 VHRDLKAENLLLDADMNIKITDFG---FSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDG 231 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+K+ L N Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 291 Query: 1175 PNTRITIAEVINNEWFKKGYQPPR---FETAEVNLDD 1276 P R T+ +++ + W G++ F E+++ D Sbjct: 292 PVKRGTLEQIMKDRWINAGHEEEELKPFVEPELDISD 328
>Q03141:MARK3_MOUSE MAP/microtubule affinity-regulating kinase 3 - Mus musculus (Mouse)| Length = 753 Score = 237 bits (605), Expect = 1e-61 Identities = 112/277 (40%), Positives = 179/277 (64%), Gaps = 3/277 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +T+G+G FAKVK AR++ TG VAIKI+DK + L + ++ RE+ MK++ HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 114 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV+ + +Y++ME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 174 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 175 VHRDLKAENLLLDADMNIKIADFG---FSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDG 231 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+K+ L N Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 291 Query: 1175 PNTRITIAEVINNEWFKKGYQPPR---FETAEVNLDD 1276 P R T+ +++ + W G++ F E+++ D Sbjct: 292 PVKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISD 328
>Q69Z98:BRSK2_MOUSE BR serine/threonine-protein kinase 2 - Mus musculus (Mouse)| Length = 735 Score = 236 bits (603), Expect = 2e-61 Identities = 111/266 (41%), Positives = 178/266 (66%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +TLG+G VK + T + VAIKI++++K L ++ +++REI+ +KLI HP+ Sbjct: 20 YRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREK-LSESVLMKVEREIAILKLIEHPH 78 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+++++V ++ +Y+V+E V+GGELFD + +GRL +ARK+F+Q+I+A+D+CHS + Sbjct: 79 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 138 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD ++++DFG+++L D LL T+CG+P+Y PEVI + YDG Sbjct: 139 CHRDLKPENLLLDERNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIRGEKYDG 195 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 KAD+WSCGVILF L+ G LPF+D NL L +K+ + F P + + L++ +++ + Sbjct: 196 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVD 255 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFE 1252 R+T+ + + W+ G P E Sbjct: 256 AARRLTLEHIQKHIWYIGGKNEPEPE 281
>Q8IWQ3:BRSK2_HUMAN BR serine/threonine-protein kinase 2 - Homo sapiens (Human)| Length = 736 Score = 236 bits (603), Expect = 2e-61 Identities = 111/266 (41%), Positives = 178/266 (66%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +TLG+G VK + T + VAIKI++++K L ++ +++REI+ +KLI HP+ Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREK-LSESVLMKVEREIAILKLIEHPH 77 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+++++V ++ +Y+V+E V+GGELFD + +GRL +ARK+F+Q+I+A+D+CHS + Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD ++++DFG+++L D LL T+CG+P+Y PEVI + YDG Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIRGEKYDG 194 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 KAD+WSCGVILF L+ G LPF+D NL L +K+ + F P + + L++ +++ + Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVD 254 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFE 1252 R+T+ + + W+ G P E Sbjct: 255 AARRLTLEHIQKHIWYIGGKNEPEPE 280
>Q05512:MARK2_MOUSE Serine/threonine-protein kinase MARK2 - Mus musculus (Mouse)| Length = 776 Score = 236 bits (602), Expect = 3e-61 Identities = 109/261 (41%), Positives = 174/261 (66%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +T+G+G FAKVK AR++ TG+ VA+KI+DK + L + ++ RE+ MK++ HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ-LNSSSLQKLFREVRIMKVLNHPN 111 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K DG Sbjct: 172 VHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKIDG 228 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK L N Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILN 288 Query: 1175 PNTRITIAEVINNEWFKKGYQ 1237 P+ R T+ +++ + W G++ Sbjct: 289 PSKRGTLEQIMKDRWMNVGHE 309
>Q9P0L2:MARK1_HUMAN Serine/threonine-protein kinase MARK1 - Homo sapiens (Human)| Length = 795 Score = 236 bits (602), Expect = 3e-61 Identities = 109/261 (41%), Positives = 173/261 (66%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +T+G+G FAKVK AR+V TG VA+KI+DK + L + ++ RE+ MK++ HPN Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 118 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLD + +K++DFG S + L T CG+P Y APE+ K YDG Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFG---FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK+L N Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLN 295 Query: 1175 PNTRITIAEVINNEWFKKGYQ 1237 P R ++ +++ + W G++ Sbjct: 296 PIKRGSLEQIMKDRWMNVGHE 316
>Q02723:RKIN1_SECCE Carbon catabolite derepressing protein kinase - Secale cereale (Rye)| Length = 502 Score = 231 bits (589), Expect = 8e-60 Identities = 121/261 (46%), Positives = 172/261 (65%), Gaps = 4/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKL---IR 625 Y LG+ LG GTFAKV A + T VAIK+L++ ++ +M + KREI ++L + Sbjct: 14 YYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRLFIDLI 73 Query: 626 HPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHS 805 HP++IR+YEV+ + I++VME G+L D I + RL+ED+AR+ FQQ+I+AV+YCH Sbjct: 74 HPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVEYCHR 133 Query: 806 RGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDG-LLHTTCGTPNYVAPEVINNK 982 V HRDLKPENLLLD+ +K++DFGLS V DG L T+CG+ NY APEVI+ K Sbjct: 134 NKVVHRDLKPENLLLDSKYNVKLADFGLS----NVMHDGHFLKTSCGSLNYAAPEVISGK 189 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKI 1162 Y G + D+WSCGVIL+ L+ G +PF+D N+ L+KKI + P + S + LI ++ Sbjct: 190 LYAGPEIDVWSCGVILYALLCGAVPFDDDNIPNLFKKIKGGTYILPIYLSDLVRDLISRM 249 Query: 1163 LDPNPNTRITIAEVINNEWFK 1225 L +P RITI E+ + WF+ Sbjct: 250 LIVDPMKRITIGEIRKHSWFQ 270
>P45894:AAPK1_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-1 -| Caenorhabditis elegans Length = 589 Score = 231 bits (589), Expect = 8e-60 Identities = 108/257 (42%), Positives = 169/257 (65%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 + + T+G+G F VK +++TG +VAIKIL++ ++ + + + EI ++ + HP+ Sbjct: 24 FVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHPH 83 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 + R++ V+++ + I++VMELV+GGELF I +G L ++R+YFQQ+I+ V YCH+ + Sbjct: 84 ITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHMI 143 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLDAN +K++DFG LS + + LL T CG+PNY APE+I+NK Y G Sbjct: 144 VHRDLKPENLLLDANKNIKIADFG---LSNYMTDGDLLSTACGSPNYAAPELISNKLYVG 200 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + DLWSCGVIL+ ++ G LPF+D N+ L+ KI ++ P A LI +L + Sbjct: 201 PEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTMLQVD 260 Query: 1175 PNTRITIAEVINNEWFK 1225 P R + ++N+ WF+ Sbjct: 261 PVKRADVKRIVNHSWFR 277
>Q9IA88:SN1L2_CHICK Serine/threonine-protein kinase SNF1-like kinase 2 - Gallus gallus| (Chicken) Length = 798 Score = 229 bits (583), Expect = 4e-59 Identities = 115/277 (41%), Positives = 174/277 (62%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ RTLG+G FA VK AR+ T VAIKI+DK + L + +I RE+ MKL+ HP+ Sbjct: 26 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR-LDPSNLEKIYREVQIMKLLNHPH 84 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+VM ++ +YIV E GE+FD + S G L E +ARK F Q+++AV+YCHS + Sbjct: 85 IIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHI 144 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLDAN +K++DFG + L T CG+P Y APEV K Y+G Sbjct: 145 VHRDLKTENLLLDANMNIKLADFGFGNF---YKSGEPLSTWCGSPPYAAPEVFEGKEYEG 201 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 D+WS GV+L+VL+ G LPF+ NL L +++ + F P + S + LI+++L + Sbjct: 202 PHLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEDCETLIRRMLVVD 261 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINS 1285 P RITI+++ ++W + + ++ ++ + NS Sbjct: 262 PTKRITISQIKQHKWMQADPSLRQQQSLSFSMQNYNS 298
>Q9R1U5:SN1L1_RAT Serine/threonine-protein kinase SNF1-like kinase 1 - Rattus| norvegicus (Rat) Length = 776 Score = 227 bits (579), Expect = 1e-58 Identities = 113/257 (43%), Positives = 166/257 (64%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ RTLG+G FA VK AR+ T VAIKI+DK + L + +I RE+ MKL+ HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR-LDSSNLEKIYREVQLMKLLNHPN 85 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+VM ++ +YIV E GE+FD + S G L E++ARK F Q+++AV+YCH+ + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHNHHI 145 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLD N +K++DFG + L T CG+P Y APEV K Y+G Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGFGNF---YKPGEPLSTWCGSPPYAAPEVFEGKEYEG 202 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GV+L+VL+ G LPF+ NL L +++ + F P + S + LI+++L + Sbjct: 203 PQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVD 262 Query: 1175 PNTRITIAEVINNEWFK 1225 P RITIA++ + W + Sbjct: 263 PAKRITIAQIRQHRWMQ 279
>P27448:MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 - Homo sapiens (Human)| Length = 776 Score = 227 bits (578), Expect = 2e-58 Identities = 113/300 (37%), Positives = 180/300 (60%), Gaps = 26/300 (8%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y L +T+G+G FAKVK AR++ TG VAIKI+DK + L + ++ RE+ MK++ HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 114 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQ------------- 775 +++++EV+ + +Y++ME +GGE+FD + + GR+KE +AR F+Q Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKVQVS 174 Query: 776 ----------LINAVDYCHSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGL 925 +++AV YCH + + HRDLK ENLLLDA+ +K++DFG S + G Sbjct: 175 FDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFS---NEFTVGGK 231 Query: 926 LHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA 1105 L T CG+P Y APE+ K YDG + D+WS GVIL+ L++G LPF+ NL L +++ + Sbjct: 232 LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 291 Query: 1106 DFSCPSWFSTSAKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPR---FETAEVNLDD 1276 + P + ST + L+K+ L NP R T+ +++ + W G++ F E+++ D Sbjct: 292 KYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISD 351
>P34244:HSL1_YEAST Probable serine/threonine-protein kinase HSL1 - Saccharomyces| cerevisiae (Baker's yeast) Length = 1518 Score = 227 bits (578), Expect = 2e-58 Identities = 118/294 (40%), Positives = 177/294 (60%), Gaps = 36/294 (12%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKH-------------KMIAQ-- 589 ++LG+TLG+G+ +V+ A+N+ETG+ AIKI+ K K H M+ Sbjct: 81 WKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNV 140 Query: 590 --------------------IKREISTMKLIRHPNVIRMYEVMASRTKIYIVMELVTGGE 709 I+REI MKLI H NV+ ++EV +++++Y+V+E V GGE Sbjct: 141 SSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGE 200 Query: 710 LFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD-ANGTLKVSDFG 886 LFD + S+G+L E +A YF+Q++ V YCHS + HRDLKPENLLLD N +K++DFG Sbjct: 201 LFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFG 260 Query: 887 LSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFED 1066 ++AL + LL T+CG+P+Y +PE++ + Y G +D+WSCG++LF L+ G+LPF D Sbjct: 261 MAALE---LPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFND 317 Query: 1067 SNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRITIAEVINNEWFKK 1228 N+ L K+ + PS S+ A+ LI KIL +P RIT E++ + KK Sbjct: 318 DNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKK 371
>P57059:SN1L1_HUMAN Serine/threonine-protein kinase SNF1-like kinase 1 - Homo sapiens| (Human) Length = 783 Score = 226 bits (577), Expect = 2e-58 Identities = 112/257 (43%), Positives = 165/257 (64%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ RTLG+G FA VK AR+ T VAIKI+DK + L + +I RE+ MKL+ HP+ Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR-LDSSNLEKIYREVQLMKLLNHPH 85 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+VM ++ +YIV E GE+FD + S G L E++ARK F Q+++AV+YCH + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHI 145 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLD N +K++DFG + L T CG+P Y APEV K Y+G Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGFGNF---YKSGEPLSTWCGSPPYAAPEVFEGKEYEG 202 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GV+L+VL+ G LPF+ NL L +++ + F P + S + LI+++L + Sbjct: 203 PQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVD 262 Query: 1175 PNTRITIAEVINNEWFK 1225 P RITIA++ + W + Sbjct: 263 PARRITIAQIRQHRWMR 279
>Q60670:SN1L1_MOUSE Serine/threonine-protein kinase SNF1-like kinase 1 - Mus musculus| (Mouse) Length = 779 Score = 222 bits (566), Expect = 4e-57 Identities = 111/257 (43%), Positives = 166/257 (64%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ RTLG+G FA VK AR+ T VAIKI+DK + L + +I RE+ MKL+ HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR-LDSSNLEKIYREVQLMKLLNHPN 85 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+VM ++ +YIV E GE+FD + S G L E++AR+ F Q+++AV+YCH+ + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCHNHHI 145 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLD+N +K++DFG + L T G+P Y APEV K Y+G Sbjct: 146 VHRDLKTENLLLDSNMDIKLADFGFGNF---YKPGEPLSTCVGSPPYAAPEVFEGKEYEG 202 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GV+L+VL+ G LPF+ NL L +++ + F P + S + LI+++L + Sbjct: 203 PQLDVWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVD 262 Query: 1175 PNTRITIAEVINNEWFK 1225 P RITIA++ + W + Sbjct: 263 PAKRITIAQIRQHRWMQ 279
>Q9H0K1:SN1L2_HUMAN Serine/threonine-protein kinase SNF1-like kinase 2 - Homo sapiens| (Human) Length = 926 Score = 221 bits (562), Expect = 1e-56 Identities = 108/255 (42%), Positives = 167/255 (65%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ TLG+G FA VK R+ T VAIKI+DK + L + +I RE+ MK++ HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQ-LDAVNLEKIYREVQIMKMLDHPH 78 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+VM +++ +Y+V E GE+FD +A+ GRL E +AR+ F Q+++AVDYCH R + Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLD N +K++DFG + LL T CG+P Y APEV + Y+G Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNF---FKSGELLATWCGSPPYAAPEVFEGQQYEG 195 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GV+L+VL+ G LPF+ L L +++ + F P + S + LI+++L + Sbjct: 196 PQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLD 255 Query: 1175 PNTRITIAEVINNEW 1219 P+ R+TIA++ ++W Sbjct: 256 PSKRLTIAQIKEHKW 270
>Q12263:GIN4_YEAST Serine/threonine-protein kinase GIN4 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1142 Score = 220 bits (561), Expect = 1e-56 Identities = 116/276 (42%), Positives = 168/276 (60%), Gaps = 18/276 (6%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDK--------------DKVLKHKMIAQI 592 ++LG TLG G+ KV+ ARN TG+ A+K++ K + I Sbjct: 19 WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGI 78 Query: 593 KREISTMKLIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQ 772 +REI MKL+ HPNV+R+Y+V + T +Y+V+E GELF+ + RG L E +A ++F+ Sbjct: 79 EREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFR 138 Query: 773 QLINAVDYCHSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPN 952 Q+I V YCH+ G+ HRDLKPENLLLD +K++DFG++AL E LL T+CG+P+ Sbjct: 139 QIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALE---TEGKLLETSCGSPH 195 Query: 953 YVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPF--EDSNLMALYKKIYKADFSCPS- 1123 Y APE+++ Y G +D+WSCGVILF L+ G LPF ED N+ L K+ K +F PS Sbjct: 196 YAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSD 255 Query: 1124 -WFSTSAKKLIKKILDPNPNTRITIAEVINNEWFKK 1228 S A+ LI+KIL +P RI +++ + +K Sbjct: 256 DEISREAQDLIRKILTVDPERRIKTRDILKHPLLQK 291
>Q8CFH6:SN1L2_MOUSE Serine/threonine-protein kinase SNF1-like kinase 2 - Mus musculus| (Mouse) Length = 931 Score = 220 bits (560), Expect = 2e-56 Identities = 108/255 (42%), Positives = 167/255 (65%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ TLG+G FA VK R+ T VAIKI+DK + L + +I RE+ MK++ HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQ-LDAVNLEKIYREVQIMKMLDHPH 78 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+VM +++ +Y+V E GE+FD +A+ GRL E +AR+ F Q+++AVDYCH R V Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKV 138 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLD N +K++DFG + LL T CG+P Y APEV + Y+G Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNF---FKTGELLATWCGSPPYAAPEVFEGQQYEG 195 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GV+L+VL+ G LPF+ L L +++ + F P + S + LI+++L + Sbjct: 196 PQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLD 255 Query: 1175 PNTRITIAEVINNEW 1219 P+ R++IA++ ++W Sbjct: 256 PSKRLSIAQIKEHKW 270
>O60285:NUAK1_HUMAN NUAK family SNF1-like kinase 1 - Homo sapiens (Human)| Length = 661 Score = 218 bits (555), Expect = 7e-56 Identities = 111/261 (42%), Positives = 167/261 (63%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YEL TLG+GT+ KVK A +G VAIK + KDK+ + + I+REI M + HP+ Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPH 114 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I +YEV ++ KI I+ME + GEL+D I+ R RL E + R +F+Q+++AV YCH GV Sbjct: 115 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 174 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK EN+LLD N +K++DFGLS L Q +D L T CG+P Y +PE++N + Y G Sbjct: 175 VHRDLKLENILLDDNCNIKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGRPYRG 231 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D W+ GV+L+ L+ G +PF+ + L ++I ++ P+ + A+ LI+ +L N Sbjct: 232 PEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWMLMVN 290 Query: 1175 PNTRITIAEVINNEWFKKGYQ 1237 P+ R TI ++ N+ W GY+ Sbjct: 291 PDRRATIEDIANHWWVNWGYK 311
>Q641K5:NUAK1_MOUSE NUAK family SNF1-like kinase 1 - Mus musculus (Mouse)| Length = 658 Score = 217 bits (552), Expect = 2e-55 Identities = 111/261 (42%), Positives = 166/261 (63%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YEL TLG+GT+ KVK A +G VAIK + KDK+ + I+REI M + HP+ Sbjct: 56 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHPH 115 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I +YEV ++ KI I+ME + GEL+D I+ R RL E + R +F+Q+++AV YCH GV Sbjct: 116 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 175 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK EN+LLD N +K++DFGLS L Q +D L T CG+P Y +PE++N + Y G Sbjct: 176 VHRDLKLENILLDDNCNIKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGRPYRG 232 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D W+ GV+L+ L+ G +PF+ + L ++I ++ P+ + A+ LI+ +L N Sbjct: 233 PEVDSWALGVLLYTLIYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWMLMVN 291 Query: 1175 PNTRITIAEVINNEWFKKGYQ 1237 P+ R TI ++ N+ W GY+ Sbjct: 292 PDRRATIEDIANHWWVNWGYK 312
>Q5REX1:SN1L2_PONPY Serine/threonine-protein kinase SNF1-like kinase 2 - Pongo pygmaeus| (Orangutan) Length = 925 Score = 214 bits (544), Expect = 1e-54 Identities = 106/255 (41%), Positives = 166/255 (65%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ TLG+G FA VK R+ T VAIKI+DK + L + +I RE+ MK++ HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQ-LDAVNLEKIYREVQIMKMLDHPH 78 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y+VM +++ +Y+V E GE+FD +A+ GRL E +AR+ F Q+++AVDYCH R + Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK ENLLLD N +K++DF + + LL T G+P Y APEV + Y+G Sbjct: 139 VHRDLKAENLLLDNNMNIKIADF---SFGNFFKSGELLATWRGSPPYAAPEVFEGQQYEG 195 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS GV+L+VL+ G LPF+ L L +++ + F P + S + LI+++L + Sbjct: 196 PQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLD 255 Query: 1175 PNTRITIAEVINNEW 1219 P+ R+TIA++ ++W Sbjct: 256 PSKRLTIAQIKEHKW 270
>Q66HE5:NUAK2_RAT NUAK family SNF1-like kinase 2 - Rattus norvegicus (Rat)| Length = 630 Score = 214 bits (544), Expect = 1e-54 Identities = 139/393 (35%), Positives = 211/393 (53%), Gaps = 22/393 (5%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE TLG+GT+ KVK AR +G VAIK + KDK+ + + I+REI M + HP+ Sbjct: 57 YEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPH 115 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I ++EV + +KI IVME + G+L+D I+ R RL E DAR +F+Q+++A+ YCH G+ Sbjct: 116 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLNERDARHFFRQIVSALHYCHQNGI 175 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK EN+LLDA+G +K++DFGLS L + + L T CG+P Y +PE++N K Y G Sbjct: 176 VHRDLKLENILLDASGNIKIADFGLSNLYHKGK---FLQTFCGSPLYASPEIVNGKPYVG 232 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D WS GV+L++L+ G +PF+ + L K+I + P + A LI+ +L N Sbjct: 233 PEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISSGAYREPC-KPSDACGLIRWLLMVN 291 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDPAQLVVERREERPAVM 1354 P R T+ +V ++ W GY E + L + +SG + RR RP + Sbjct: 292 PIRRATLEDVASHWWVNWGYSTRIGE--QEALREGGHPSGDSGRASMADWLRRSSRPLLE 349 Query: 1355 NAFELIS-----TSQGLNLGTLFEKQTDSVK--RETRFASRL---PANEILSK------- 1483 N ++ S G + G E+Q K +E A L PA + S+ Sbjct: 350 NGAKVCSFFKQHVPGGGSTGPGLERQHSLKKSRKENDMAQTLQNDPAEDTSSRPGKNSLK 409 Query: 1484 -----IEAAAGPMGFNVQKRNYKLKLQGENPGR 1567 ++ A P VQ+ +L+ PG+ Sbjct: 410 LPKGILKKKASPSSGEVQEGPQELRPVSNTPGQ 442
>Q9NRH2:SNRK_HUMAN SNF-related serine/threonine-protein kinase - Homo sapiens (Human)| Length = 765 Score = 212 bits (540), Expect = 4e-54 Identities = 117/308 (37%), Positives = 183/308 (59%), Gaps = 4/308 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L +TLG G FA VK AR+V TGE VA+K++DK K L + +E+ MKL++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPN 74 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGR-LKEDDARKYFQQLINAVDYCHSRG 811 ++R+YEV+ ++TK+Y+++EL GG++FD I L ED A+KYF Q+++A+ YCH Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134 Query: 812 VYHRDLKPENLLL-DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGY 988 V HRDLKPEN++ + G +K++DFG S Q ++ L T+CG+ Y APE++ Y Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEY 191 Query: 989 DGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILD 1168 D D+WS GVILF+L+ G PF+++N I ++ PS S K LI ++L Sbjct: 192 DAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQ 251 Query: 1169 PNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDP--AQLVVERREER 1342 +P R ++ E+ N+ W +G P + L ++ E + ++V+ +R Sbjct: 252 RDPKRRASLEEIENHPWL-QGVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADR 310 Query: 1343 PAVMNAFE 1366 A++ A E Sbjct: 311 DAIVEALE 318
>Q75V57:SAPK9_ORYSJ Serine/threonine-protein kinase SAPK9 - Oryza sativa subsp. japonica| (Rice) Length = 361 Score = 211 bits (538), Expect = 7e-54 Identities = 127/325 (39%), Positives = 180/325 (55%), Gaps = 12/325 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YEL + +G G F + RN +G+ VA+K +D+ + K+ ++REI + +RHPN Sbjct: 22 YELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGE----KIDENVQREIINHRSLRHPN 77 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV+ + T + IVME +GGELF++I S GR ED+AR +FQQLI+ V YCHS V Sbjct: 78 IIRFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQV 137 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + LK+ DFG S + +LH +T GTP Y+APEV+ Sbjct: 138 CHRDLKLENTLLDGSTAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLL 190 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTS 1138 K YDG AD+WSCGV L+V++ G PFED N +KI +S P + S Sbjct: 191 KKEYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIQKILGVQYSIPDYVHISPE 250 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDPAQL 1318 + LI +I NP +RIT+ E+ N+ WF K +L D + N+ +P Q Sbjct: 251 CRDLITRIFVGNPASRITMPEIKNHPWFMK--------NIPADLMDDGMVSNQYEEPDQP 302 Query: 1319 VVERREERPAVMNAFELISTSQGLN 1393 + E + A + + G+N Sbjct: 303 MQNMNEIMQILAEATIPAAGTSGIN 327
>Q5R7G9:NUAK2_PONPY NUAK family SNF1-like kinase 2 - Pongo pygmaeus (Orangutan)| Length = 628 Score = 211 bits (538), Expect = 7e-54 Identities = 112/260 (43%), Positives = 164/260 (63%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE TLG+GT+ KVK AR +G VAIK + KDK+ + + I+REI M + HP+ Sbjct: 53 YEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I ++EV + +KI IVME + G+L+D I+ R +L E +AR +F+Q+++AV YCH V Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK EN+LLDANG +K++DFGLS L Q + L T CG+P Y +PE++N K Y G Sbjct: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGK---FLQTFCGSPLYASPEIVNGKPYTG 228 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D WS GV+L++L+ G +PF+ + L K+I + P + A LI+ +L N Sbjct: 229 PEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP-KPSDACGLIRWLLMVN 287 Query: 1175 PNTRITIAEVINNEWFKKGY 1234 P R T+ +V ++ W GY Sbjct: 288 PTRRATLEDVASHWWVNWGY 307
>Q9H093:NUAK2_HUMAN NUAK family SNF1-like kinase 2 - Homo sapiens (Human)| Length = 628 Score = 211 bits (538), Expect = 7e-54 Identities = 112/260 (43%), Positives = 164/260 (63%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE TLG+GT+ KVK AR +G VAIK + KDK+ + + I+REI M + HP+ Sbjct: 53 YEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I ++EV + +KI IVME + G+L+D I+ R +L E +AR +F+Q+++AV YCH V Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK EN+LLDANG +K++DFGLS L Q + L T CG+P Y +PE++N K Y G Sbjct: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGK---FLQTFCGSPLYASPEIVNGKPYTG 228 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D WS GV+L++L+ G +PF+ + L K+I + P + A LI+ +L N Sbjct: 229 PEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP-KPSDACGLIRWLLMVN 287 Query: 1175 PNTRITIAEVINNEWFKKGY 1234 P R T+ +V ++ W GY Sbjct: 288 PTRRATLEDVASHWWVNWGY 307
>P87050:CDR2_SCHPO Mitosis inducer protein kinase cdr2 - Schizosaccharomyces pombe| (Fission yeast) Length = 775 Score = 211 bits (536), Expect = 1e-53 Identities = 105/308 (34%), Positives = 183/308 (59%), Gaps = 9/308 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +ELG +LG G + A++ ETG+ +K + L A+I+ E+ ++LI HPN Sbjct: 10 WELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPN 69 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+++ +V++++ ++++V+E + GGELFD + +G E D K+ Q++ ++YCH + Sbjct: 70 VLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHI 129 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENL LDA+G++K+ +FG++++ Q + LL T+CG+P+Y +PE+I + YDG Sbjct: 130 CHRDLKPENLYLDAHGSIKIGEFGMASIQQPGK---LLQTSCGSPHYASPEIIMGRSYDG 186 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 +D+WSCG+I F L+ G LPF+D N+ +L K+ + F PS S A+ L+ ++LD + Sbjct: 187 CASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPSNISPQAQHLLYRMLDVD 246 Query: 1175 PNTRITIAEVINNEWFKKGYQP---------PRFETAEVNLDDINSIFNESGDPAQLVVE 1327 +TRIT+ ++ + + P P + + ++ +F S DP L + Sbjct: 247 SSTRITMEQIREHPFLSCFVHPNISIPIISAPIQPIDPLIVQHLSLVFRCSDDPMPLYEK 306 Query: 1328 RREERPAV 1351 + P V Sbjct: 307 LASQSPLV 314
>Q5N942:SAPK4_ORYSJ Serine/threonine-protein kinase SAPK4 - Oryza sativa subsp. japonica| (Rice) Length = 360 Score = 210 bits (535), Expect = 1e-53 Identities = 121/313 (38%), Positives = 174/313 (55%), Gaps = 16/313 (5%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE R +G G F + RN ET E VA+K +++ H++ + REI + +RHPN Sbjct: 4 YEAVRDIGSGNFGVARLMRNRETRELVAVKCIERG----HRIDENVYREIINHRSLRHPN 59 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV+ + T + IVME GGELFD+I RGR ED+AR +FQQLI V YCH + Sbjct: 60 IIRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHHMQI 119 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN+LLD + LK+ DFG S + +LH + GTP Y+APEV++ Sbjct: 120 CHRDLKLENVLLDGSPAPRLKICDFGYS-------KSSVLHSRPKSAVGTPAYIAPEVLS 172 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSWFSTSA- 1141 + YDG AD+WSCGV L+V++ G PFED N+ ++I + P + SA Sbjct: 173 RREYDGKLADVWSCGVTLYVMLVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYVHISAE 232 Query: 1142 -KKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNL----DDINSIFNESGD 1306 K+LI +I NP RIT+ E+ ++ WF K ETA+ + + S +++ + Sbjct: 233 CKQLIARIFVNNPLRRITMKEIKSHPWFLKNLPRELTETAQAMYYRRDNSVPSFSDQTSE 292 Query: 1307 PAQLVVERREERP 1345 +V+ P Sbjct: 293 EIMKIVQEARTMP 305
>Q8BZN4:NUAK2_MOUSE NUAK family SNF1-like kinase 2 - Mus musculus (Mouse)| Length = 639 Score = 210 bits (534), Expect = 2e-53 Identities = 124/318 (38%), Positives = 184/318 (57%), Gaps = 11/318 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE TLG+GT+ KVK AR +G VAIK + KDK+ + + I+REI M + HP+ Sbjct: 57 YEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPH 115 Query: 635 VIRMYEVMASR--------TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAV 790 +I ++EV SR +KI IVME + G+L+D I+ R RL E DAR +F+Q+++A+ Sbjct: 116 IIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSAL 175 Query: 791 DYCHSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEV 970 YCH G+ HRDLK EN+LLDANG +K++DFGLS L + + L T CG+P Y +PE+ Sbjct: 176 HYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGK---FLQTFCGSPLYASPEI 232 Query: 971 INNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKL 1150 +N K Y G + D WS GV+L++L+ G +PF+ + L K+I + P + A L Sbjct: 233 VNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISNGAYREPP-KPSDACGL 291 Query: 1151 IKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDPAQLVVE- 1327 I+ +L NP R T+ +V ++ W GY T + + + SGD + + Sbjct: 292 IRWLLMVNPTRRATLEDVASHWWVNWGY-----TTGVGEQEALREGGHPSGDFGRASMAD 346 Query: 1328 --RREERPAVMNAFELIS 1375 RR RP + N ++ S Sbjct: 347 WLRRSSRPLLENGAKVCS 364
>Q75LR7:SAPK1_ORYSJ Serine/threonine-protein kinase SAPK1 - Oryza sativa subsp. japonica| (Rice) Length = 342 Score = 209 bits (531), Expect = 4e-53 Identities = 121/309 (39%), Positives = 172/309 (55%), Gaps = 24/309 (7%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+ R +G G F K R+V T A+K +++ K+ ++REI + ++HPN Sbjct: 4 YEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIERGL----KIDEHVQREIMNHRSLKHPN 59 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV+ + T + IVME GGELF++I + GR ED+AR +FQQLI+ V YCHS V Sbjct: 60 IIRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQV 119 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + T LK+ DFG S + +LH +T GTP Y+APEV++ Sbjct: 120 CHRDLKLENTLLDGSVTPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLS 172 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSWFSTSA- 1141 K YDG AD+WSCGV L+V++ G PFED N +I +S P + SA Sbjct: 173 RKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDDPRNFRKTITRILSVQYSIPDYVRVSAD 232 Query: 1142 -KKLIKKILDPNPNTRITIAEVINNEWF------------KKGYQPPRFETAEVNLDDIN 1282 + L+ +I NP RITI E+ N+ WF ++ Q T +L+++ Sbjct: 233 CRHLLSRIFVGNPEQRITIPEIKNHPWFLKNLPIEMTDEYQRSMQLADMNTPSQSLEEVM 292 Query: 1283 SIFNESGDP 1309 +I E+ P Sbjct: 293 AIIQEARKP 301
>P25389:KCC4_YEAST Probable serine/threonine-protein kinase KCC4 - Saccharomyces| cerevisiae (Baker's yeast) Length = 1037 Score = 207 bits (528), Expect = 1e-52 Identities = 111/274 (40%), Positives = 167/274 (60%), Gaps = 16/274 (5%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDK------------DKVLKHKMIAQIKR 598 ++LG TLG G+ KV+ A++ TG A+K++ K D VL + I+R Sbjct: 21 WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYN----IER 76 Query: 599 EISTMKLIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQL 778 EI MKL+ HPNV+ +Y+V + +Y+++E GELF+ + G L E +A F+Q+ Sbjct: 77 EIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQI 136 Query: 779 INAVDYCHSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYV 958 I + YCH+ G+ HRDLKPENLLLD+ +K++DFG++AL + LL T+CG+P+Y Sbjct: 137 IIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQ---TDADLLETSCGSPHYA 193 Query: 959 APEVINNKGYDGAKADLWSCGVILFVLMAGYLPF--EDSNLMALYKKIYKADFSCP--SW 1126 APE+++ Y+G +D+WSCGVILF L+ G LPF E+ N+ L K+ K F P + Sbjct: 194 APEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTE 253 Query: 1127 FSTSAKKLIKKILDPNPNTRITIAEVINNEWFKK 1228 S A+ LI KIL +P RI I +++++ KK Sbjct: 254 ISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKK 287
>Q63553:SNRK_RAT SNF-related serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 746 Score = 207 bits (527), Expect = 1e-52 Identities = 114/308 (37%), Positives = 182/308 (59%), Gaps = 4/308 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L +TLG G FA VK AR+V TGE VA+K++DK K L + +E+ MKL++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPN 74 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGR-LKEDDARKYFQQLINAVDYCHSRG 811 ++R+YEV+ ++TK+Y+++EL GG++FD I L ED A+KYF Q+++A+ YCH Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134 Query: 812 VYHRDLKPENLLL-DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGY 988 V HRDLKPEN++ + G +K++DFG S Q ++ L T+CG+ Y APE++ Y Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEY 191 Query: 989 DGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILD 1168 D D+WS GVILF+L+ G PF+++N I ++ P S + LI ++L Sbjct: 192 DAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQ 251 Query: 1169 PNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDP--AQLVVERREER 1342 +P R ++ E+ ++ W +G P + L ++ E + ++V+ +R Sbjct: 252 RDPKRRASLEEIESHPWL-QGVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADR 310 Query: 1343 PAVMNAFE 1366 A++ A E Sbjct: 311 DAIVEALE 318
>Q8VDU5:SNRK_MOUSE SNF-related serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 748 Score = 207 bits (527), Expect = 1e-52 Identities = 114/308 (37%), Positives = 182/308 (59%), Gaps = 4/308 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L +TLG G FA VK AR+V TGE VA+K++DK K L + +E+ MKL++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPN 74 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGR-LKEDDARKYFQQLINAVDYCHSRG 811 ++R+YEV+ ++TK+Y+++EL GG++FD I L ED A+KYF Q+++A+ YCH Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134 Query: 812 VYHRDLKPENLLL-DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGY 988 V HRDLKPEN++ + G +K++DFG S Q ++ L T+CG+ Y APE++ Y Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEY 191 Query: 989 DGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILD 1168 D D+WS GVILF+L+ G PF+++N I ++ P S + LI ++L Sbjct: 192 DAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQ 251 Query: 1169 PNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDP--AQLVVERREER 1342 +P R ++ E+ ++ W +G P + L ++ E + ++V+ +R Sbjct: 252 RDPKRRASLEEIESHPWL-QGVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADR 310 Query: 1343 PAVMNAFE 1366 A++ A E Sbjct: 311 DAIVEALE 318
>Q84TC6:SAPK2_ORYSA Serine/threonine-protein kinase SAPK2 - Oryza sativa (Rice)| Length = 339 Score = 207 bits (526), Expect = 2e-52 Identities = 118/291 (40%), Positives = 166/291 (57%), Gaps = 14/291 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+ + +G G F K R+V T E A+K +++ + K+ ++REI + +RHPN Sbjct: 4 YEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQ----KIDENVQREIMNHRSLRHPN 59 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R EV+ + T + IVME GGELF++I S GR ED+AR +FQQLI+ V YCHS + Sbjct: 60 IVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQI 119 Query: 815 YHRDLKPENLLLDAN--GTLKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + LK+ DFG S + LLH +T GTP Y+APEV+ Sbjct: 120 CHRDLKLENTLLDGSIAPRLKICDFGYS-------KSSLLHSQPKSTVGTPAYIAPEVLA 172 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTS 1138 K YDG AD+WSCGV L+V++ G PFED N +I + P + S Sbjct: 173 RKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYMVPDYVRVSME 232 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAE--VNLDDINS 1285 + L+ +I NP RITI E+ N+ WF K + + V ++DIN+ Sbjct: 233 CRHLLSRIFVANPEQRITIPEIKNHPWFLKNLPIEMTDEYQMSVQMNDINT 283
>Q75H77:SAPKA_ORYSJ Serine/threonine-protein kinase SAPK10 - Oryza sativa subsp. japonica| (Rice) Length = 362 Score = 206 bits (525), Expect = 2e-52 Identities = 125/312 (40%), Positives = 174/312 (55%), Gaps = 26/312 (8%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YEL R +G G F + R+ G+ VA+K +++ K+ ++REI + +RHPN Sbjct: 23 YELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGD----KIDENVQREIINHRSLRHPN 78 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV+ + T + IVME +GGELF++I + GR ED+AR +FQQLI+ V YCHS V Sbjct: 79 IIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQV 138 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + LK+ DFG S + +LH +T GTP Y+APEV+ Sbjct: 139 CHRDLKLENTLLDGSTAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLL 191 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTS 1138 K YDG AD+WSCGV L+V++ G PFED N ++I +S P + S Sbjct: 192 KKEYDGKIADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILGVQYSIPDYVHISPE 251 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFKKG--------------YQPPRFETAEVNLDD 1276 + LI +I NP TRI+I E+ N+ WF K Y+ P E ++D+ Sbjct: 252 CRDLIARIFVANPATRISIPEIRNHPWFLKNLPADLMDDSKMSSQYEEP--EQPMQSMDE 309 Query: 1277 INSIFNESGDPA 1312 I I E+ PA Sbjct: 310 IMQILAEATIPA 321
>Q75V63:SAPK3_ORYSA Serine/threonine-protein kinase SAPK3 - Oryza sativa (Rice)| Length = 334 Score = 204 bits (519), Expect = 1e-51 Identities = 119/303 (39%), Positives = 170/303 (56%), Gaps = 12/303 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE + LG G F + R+ + E VA+K +++ K K+ ++REI + +RHPN Sbjct: 5 YEALKELGAGNFGVARLVRDKRSKELVAVKYIERGK----KIDENVQREIINHRSLRHPN 60 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV + T + IVME GGELF++I + GR ED+AR +FQQLI+ V YCHS + Sbjct: 61 IIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLEI 120 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + T +K+ DFG S + LLH +T GTP Y+APEV++ Sbjct: 121 CHRDLKLENTLLDGSPTPRVKICDFGYS-------KSALLHSKPKSTVGTPAYIAPEVLS 173 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTS 1138 K YDG AD+WSCGV L+V++ G PFED N +I +S P + S+ Sbjct: 174 RKEYDGKVADVWSCGVTLYVMLVGSYPFEDPGDPRNFRKTISRILGVQYSIPDYVRVSSD 233 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDPAQL 1318 ++L+ +I +P+ RITI E+ + WF K E + + D ++ P Q Sbjct: 234 CRRLLSQIFVADPSKRITIPEIKKHTWFLKNLPKEISEREKADYKD-----TDAAPPTQA 288 Query: 1319 VVE 1327 V E Sbjct: 289 VEE 291
>Q68UT7:HUNK_PANTR Hormonally up-regulated neu tumor-associated kinase - Pan troglodytes| (Chimpanzee) Length = 714 Score = 204 bits (519), Expect = 1e-51 Identities = 107/260 (41%), Positives = 162/260 (62%), Gaps = 4/260 (1%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQ-IKREISTMKLIRHPNVIR 643 R LGEG+FAKV+ +V TGE VAIK++DK + K + + ++RE ++IRHPN+ + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 644 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 823 + +++ + Y+VMEL GG L KI + RL+E +AR+Y +QLI+AV++ H GV HR Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHR 185 Query: 824 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 1003 DLK ENLLLD + +K+ DFGLS + + T CG+P Y APE++ K Y G K Sbjct: 186 DLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKI 244 Query: 1004 DLWSCGVILFVLMAGYLPF--EDSNLMALYKKIYKADFS-CPSWFSTSAKKLIKKILDPN 1174 D+WS GV ++ ++ G LPF E +L ALY+K+ + + P+ ST A ++ +L+P+ Sbjct: 245 DVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPD 304 Query: 1175 PNTRITIAEVINNEWFKKGY 1234 P R I + + N W + Y Sbjct: 305 PVKRPNIQQALANRWLNENY 324
>P57058:HUNK_HUMAN Hormonally up-regulated neu tumor-associated kinase - Homo sapiens| (Human) Length = 714 Score = 204 bits (519), Expect = 1e-51 Identities = 107/260 (41%), Positives = 162/260 (62%), Gaps = 4/260 (1%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQ-IKREISTMKLIRHPNVIR 643 R LGEG+FAKV+ +V TGE VAIK++DK + K + + ++RE ++IRHPN+ + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 644 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 823 + +++ + Y+VMEL GG L KI + RL+E +AR+Y +QLI+AV++ H GV HR Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHR 185 Query: 824 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 1003 DLK ENLLLD + +K+ DFGLS + + T CG+P Y APE++ K Y G K Sbjct: 186 DLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKI 244 Query: 1004 DLWSCGVILFVLMAGYLPF--EDSNLMALYKKIYKADFS-CPSWFSTSAKKLIKKILDPN 1174 D+WS GV ++ ++ G LPF E +L ALY+K+ + + P+ ST A ++ +L+P+ Sbjct: 245 DVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPD 304 Query: 1175 PNTRITIAEVINNEWFKKGY 1234 P R I + + N W + Y Sbjct: 305 PVKRPNIQQALANRWLNENY 324
>Q6ZI44:SAPK6_ORYSJ Serine/threonine-protein kinase SAPK6 - Oryza sativa subsp. japonica| (Rice) Length = 365 Score = 203 bits (517), Expect = 2e-51 Identities = 117/281 (41%), Positives = 158/281 (56%), Gaps = 12/281 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YEL + +G G F + RN ET E VA+K + + K+ + REI + +RHPN Sbjct: 4 YELLKDIGSGNFGVARLMRNRETKELVAMKYIPRGL----KIDENVAREIINHRSLRHPN 59 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV+ + T + IVME GGELFD+I S GR ED++R +FQQLI V YCH + Sbjct: 60 IIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHFMQI 119 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + LK+ DFG S + LLH +T GTP Y+APEV++ Sbjct: 120 CHRDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSKPKSTVGTPAYIAPEVLS 172 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTS 1138 + YDG AD+WSCGV L+V++ G PFED N +I + P + S Sbjct: 173 RREYDGKMADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIVSIQYKIPEYVHISQD 232 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAE 1261 ++L+ +I NP RITI E+ N+ WF K E A+ Sbjct: 233 CRQLLSRIFVANPAKRITIREIRNHPWFMKNLPRELTEAAQ 273
>O13945:PPK9_SCHPO Protein kinase domain-containing protein ppk9 - Schizosaccharomyces| pombe (Fission yeast) Length = 532 Score = 203 bits (517), Expect = 2e-51 Identities = 99/255 (38%), Positives = 161/255 (63%), Gaps = 1/255 (0%) Frame = +2 Query: 461 LGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVI 640 LGRTLG+G AKVK ++ +T E VA+K++ D++ +++RE++ ++ + HPN+I Sbjct: 25 LGRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKRLQREVTILRQLHHPNII 84 Query: 641 RMYEVMASRTKIYIVMEL-VTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVY 817 +Y+V R Y V+ L +L + RL E RK F+Q+++A+DYCH V Sbjct: 85 TLYQVF--RVPKYTVLALEYMDTDLHSMVVKHNRLDECTTRKIFRQIVHAIDYCHLHRVA 142 Query: 818 HRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGA 997 HRDLK EN+LL+ + +K++DFGLS + + L T+CGTP+Y APEVI + YDG Sbjct: 143 HRDLKLENILLNKDLVVKLTDFGLSNF---MLDGSFLSTSCGTPHYAAPEVIQGRYYDGC 199 Query: 998 KADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNP 1177 D+W CG++L++++ G PFED + + ++ K ++ PS+ S+SA LI+++L P Sbjct: 200 DVDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCKGIYTIPSFVSSSASDLIRQMLMVLP 259 Query: 1178 NTRITIAEVINNEWF 1222 +RI +AE++ + WF Sbjct: 260 TSRIKVAEIMQHPWF 274
>O88866:HUNK_MOUSE Hormonally up-regulated neu tumor-associated kinase - Mus musculus| (Mouse) Length = 714 Score = 203 bits (517), Expect = 2e-51 Identities = 109/260 (41%), Positives = 161/260 (61%), Gaps = 4/260 (1%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQ-IKREISTMKLIRHPNVIR 643 R LGEG+FAKV+ +V TGE VAIK++DK + K + + ++RE ++IRHPN+ + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 644 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 823 + +++ + Y+VMEL GG L KI + RL E +AR+Y +QLI+AV++ H GV HR Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHR 185 Query: 824 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 1003 DLK ENLLLD + +K+ DFGLS + + T CG+P Y APE++ K Y G K Sbjct: 186 DLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKI 244 Query: 1004 DLWSCGVILFVLMAGYLPF--EDSNLMALYKK-IYKADFSCPSWFSTSAKKLIKKILDPN 1174 D+WS GV ++ ++ G LPF E +L ALY+K + KA P+ ST A ++ +L+P+ Sbjct: 245 DVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPD 304 Query: 1175 PNTRITIAEVINNEWFKKGY 1234 P R I + + N W + Y Sbjct: 305 PVKRPNIQQALANRWLNENY 324
>Q7XQP4:SAPK7_ORYSJ Serine/threonine-protein kinase SAPK7 - Oryza sativa subsp. japonica| (Rice) Length = 359 Score = 203 bits (516), Expect = 2e-51 Identities = 117/281 (41%), Positives = 158/281 (56%), Gaps = 12/281 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YEL + +G G F + RN ET E VA+K + + K+ + REI + +RHPN Sbjct: 4 YELLKDIGAGNFGVARLMRNKETKELVAMKYIPRGL----KIDENVAREIINHRSLRHPN 59 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV+ + T + IVME GGELFD+I + GR ED+AR +FQQLI V YCH + Sbjct: 60 IIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHFMQI 119 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + LK+ DFG S + LLH +T GTP Y+APEV++ Sbjct: 120 CHRDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSKPKSTVGTPAYIAPEVLS 172 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTS 1138 + YDG AD+WSCGV L+V++ G PFED N +I + P + S Sbjct: 173 RREYDGKTADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYVHVSQD 232 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAE 1261 ++L+ +I NP RITI E+ N+ WF K E A+ Sbjct: 233 CRQLLSRIFVANPAKRITIREIRNHPWFLKNLPRELTEAAQ 273
>P43292:ASK2_ARATH Serine/threonine-protein kinase ASK2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 353 Score = 202 bits (514), Expect = 4e-51 Identities = 117/310 (37%), Positives = 173/310 (55%), Gaps = 24/310 (7%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ + LG G F + R+ +T E VA+K +++ + K+ + REI + ++HPN Sbjct: 4 YDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGR----KIDENVAREIINHRSLKHPN 59 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV+ + T + IVME +GGELFD+I + GR E +AR +FQQLI VDYCHS + Sbjct: 60 IIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSLQI 119 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + LK+ DFG S + +LH +T GTP Y+APEV++ Sbjct: 120 CHRDLKLENTLLDGSPAPLLKICDFGYS-------KSSILHSRPKSTVGTPAYIAPEVLS 172 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTS 1138 + YDG AD+WSCGV L+V++ G PFED N ++I + P + S Sbjct: 173 RREYDGKHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQE 232 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEV------------NLDDIN 1282 K L+ +I N RIT+ E+ N+ W+ K E+A+ +++DI Sbjct: 233 CKHLLSRIFVTNSAKRITLKEIKNHPWYLKNLPKELLESAQAAYYKRDTSFSLQSVEDIM 292 Query: 1283 SIFNESGDPA 1312 I E+ +PA Sbjct: 293 KIVGEARNPA 302
>P22987:KIN1_SCHPO Protein kinase kin1 - Schizosaccharomyces pombe (Fission yeast)| Length = 891 Score = 202 bits (513), Expect = 5e-51 Identities = 107/281 (38%), Positives = 162/281 (57%), Gaps = 18/281 (6%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDK--DKVLKHKMIAQIK----------- 595 Y LG+T+G G+ KVK A +++TGE AIKI+ + + K K A + Sbjct: 125 YVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNK 184 Query: 596 -----REISTMKLIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDAR 760 RE + L+RHP + +V + + Y+V E V GG++ D I S G+LKE AR Sbjct: 185 EIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQAR 244 Query: 761 KYFQQLINAVDYCHSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTC 940 K+ +Q+ +A+ Y H V HRDLK EN+L+ G +K+ DFGLS L R L T C Sbjct: 245 KFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNL---YRRQSRLRTFC 301 Query: 941 GTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCP 1120 G+ + APE++N + Y G + D+WS G++L+VL+ G +PF+D N+ AL+ KI K P Sbjct: 302 GSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYP 361 Query: 1121 SWFSTSAKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPP 1243 S+ S+ K L+ ++L +P R T+ EV+N+ W + Y+ P Sbjct: 362 SYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWMIRNYEGP 402
>Q02066:AAIP_WHEAT Abscisic acid-inducible protein kinase - Triticum aestivum (Wheat)| Length = 332 Score = 201 bits (510), Expect = 1e-50 Identities = 111/263 (42%), Positives = 153/263 (58%), Gaps = 12/263 (4%) Frame = +2 Query: 476 GEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRMYEV 655 G G F K R+V T E+ A+K +++ HK+ ++REI + ++HPN+IR EV Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIERG----HKIDEHVQREIMNHRSLKHPNIIRFKEV 56 Query: 656 MASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKP 835 + + T + IVME +GGELF +I + GR ED+ R +FQQLI+ V YCHS V HRDLK Sbjct: 57 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSMQVCHRDLKL 116 Query: 836 ENLLLDAN--GTLKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNKGYDGA 997 EN LLD + LK+ DFG S + +LH +T GTP Y+APEV++ + YDG Sbjct: 117 ENTLLDGSVAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLSRREYDGK 169 Query: 998 KADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSWFSTSAK--KLIKK 1159 AD+WSCGV L+V++ G PFED N +I +S P + S L+ + Sbjct: 170 VADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYSVPDYVRVSMDCIHLLSR 229 Query: 1160 ILDPNPNTRITIAEVINNEWFKK 1228 I NP RITI E+ N+ WF K Sbjct: 230 IFVGNPQQRITIPEIKNHPWFLK 252
>Q6DE87:CHK1_XENLA Serine/threonine-protein kinase Chk1 - Xenopus laevis (African clawed| frog) Length = 474 Score = 200 bits (509), Expect = 2e-50 Identities = 145/460 (31%), Positives = 227/460 (49%), Gaps = 42/460 (9%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 ++L +TLGEG + +V+ A N +T E VA+KI+D + IK+EI +++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAADCP--ENIKKEICINRMLSHTN 66 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R Y Y+ +E GGELFD+I + E DA+K+FQQLI V+Y HS G+ Sbjct: 67 IVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHSIGI 126 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLLD LK+SDFGL+ + + ++ LL+ CGT YVAPE+I ++ + Sbjct: 127 THRDIKPENLLLDERDQLKISDFGLATVFRHNGKERLLNKMCGTLPYVAPELIKSRAFHA 186 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSN-LMALYKKIYKADFSCPSWFSTSAK--KLIKKIL 1165 D+WSCG++L ++AG LP++ N + Y + + W SA L+ K+L Sbjct: 187 DPVDVWSCGIVLTAMLAGELPWDQPNEVCQEYCDWKEKNHYLTPWKKISATPLALLCKML 246 Query: 1166 DPNPNTRITIAEVINNEWF----KKGYQPPRFETA----------EVNLDDINSIFNESG 1303 NP +RITI ++ + WF KKG + R + ++ D S F+ S Sbjct: 247 TENPQSRITIPDIKKDRWFTEIIKKGLKRSRVISGGSSDSSVLCKQIRSDIDISHFSHSE 306 Query: 1304 DPAQLVVERREERPAV----MNAFELISTSQG---------------LN---LGTLFEKQ 1417 + L + E R A+ N+ + + QG LN +GT Q Sbjct: 307 EKTALSSTQPEPRTALATWDSNSSYIDNLVQGKGISFSQPACPDNMLLNSQLIGTPGSSQ 366 Query: 1418 T---DSVKRETRFASRLPANEILSKIEAAAGPMGFNVQKRNYKLKLQGENPGRKGQLAIA 1588 VKR TRF +++ A S + MG+ ++K R +L Sbjct: 367 NVWQRLVKRMTRFFTKVNAESSYSNLMDTCEKMGYVLKKSCANEVTLSTTDRRNNKLIFK 426 Query: 1589 TEVFEVTPSLYMVELRKSNGDTLEFHKFYHSISNGLKDVM 1708 + E+ + +++ R S GD LEF + + I + V+ Sbjct: 427 VNLVEMEDRI-LLDFRLSKGDGLEFKRHFLKIKKKMDAVV 465
>Q8BHI9:NIM1_MOUSE Serine/threonine-protein kinase NIM1 - Mus musculus (Mouse)| Length = 436 Score = 200 bits (508), Expect = 2e-50 Identities = 100/271 (36%), Positives = 162/271 (59%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y + +G G F++VK + T E VAIKILDK K L K + REIS+M+ + HPN Sbjct: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTK-LDQKTQRLLSREISSMEKLHHPN 132 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+YEV+ + +K+++VME GGELF KI++ G+L E +++ F Q+++AV + H + Sbjct: 133 IVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQI 192 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK EN+ + +KV DFG S +S ++ +L+T CG+P Y APE+ ++ Y G Sbjct: 193 IHRDLKAENVFYTSRTCVKVGDFGFSTVS---KKGEMLNTFCGSPPYAAPELFRDQHYVG 249 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 D+W+ GV+L+ ++ G +PF + L K I + ++ P S +LI+ +L P Sbjct: 250 VYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPT 309 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFETAEVN 1267 P R I +++NEW + P E +++ Sbjct: 310 PTERYGINYIMSNEWMRGVPYPTPLEPFQLD 340
>Q01919:KIN4_YEAST Serine/threonine-protein kinase KIN4 - Saccharomyces cerevisiae| (Baker's yeast) Length = 800 Score = 199 bits (507), Expect = 3e-50 Identities = 109/271 (40%), Positives = 166/271 (61%), Gaps = 14/271 (5%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKF-----ARNVETGENVAIKILDKDKVLKHK-MIAQIKREISTMK 616 Y +G TLGEG F KVK + + E + VAIK++ +D + K +I REI+ +K Sbjct: 46 YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALK 105 Query: 617 LIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDY 796 + HPN+I + EV+ + I IV+E V+GGE + I + RLKE A + F QLI+ V+Y Sbjct: 106 HLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNY 165 Query: 797 CHSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPE-VI 973 H +G+ HRDLK ENLLLD + L ++DFG +++ ++ L+ T+CG+P Y APE V+ Sbjct: 166 MHYKGLVHRDLKLENLLLDKHENLVITDFGF--VNEFFEDNELMKTSCGSPCYAAPELVV 223 Query: 974 NNKGYDGAKADLWSCGVILFVLMAGYLPFED-------SNLMALYKKIYKADFSCPSWFS 1132 + K Y+ KAD+WSCGVIL+ ++AGYLP++D ++ LYK I + P + + Sbjct: 224 STKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYIT 283 Query: 1133 TSAKKLIKKILDPNPNTRITIAEVINNEWFK 1225 + L+++IL PNP RI + + + W K Sbjct: 284 PIPRDLLRRILVPNPRRRINLQTIKRHVWLK 314
>Q91819:STK6L_XENLA Serine/threonine-protein kinase Eg2-like - Xenopus laevis (African| clawed frog) Length = 408 Score = 199 bits (506), Expect = 3e-50 Identities = 100/264 (37%), Positives = 155/264 (58%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR E+ +A+K+L K ++ K + Q++RE+ +RHPN Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPN 199 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y +++Y++++ GGELF ++ R + + Y +QL A+ YCHS+ V Sbjct: 200 ILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHSKKV 259 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL +NG LK++DFG S + R T CGT +Y+ PE+I + +D Sbjct: 260 IHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD- 314 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLWS GV+ + + G PFE Y++I K +F P + S AK L+ K+L N Sbjct: 315 EKVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEAKDLVSKLLKHN 374 Query: 1175 PNTRITIAEVINNEWFKKGYQPPR 1246 PN R+ + V+ + W K Q P+ Sbjct: 375 PNHRLPLKGVLEHPWIVKNSQQPK 398
>Q8IU85:KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D - Homo sapiens| (Human) Length = 385 Score = 199 bits (506), Expect = 3e-50 Identities = 129/382 (33%), Positives = 199/382 (52%), Gaps = 10/382 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E TLG G F++V A TG+ A+K + K K LK K + I+ EI+ ++ I+H N Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPK-KALKGKE-SSIENEIAVLRKIKHEN 80 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + ++ S +Y+VM+LV+GGELFD+I +G E DA +Q+++AV Y H G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 815 YHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLL D + +SDFGLS + + ++ T CGTP YVAPEV+ K Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSKME---GKGDVMSTACGTPGYVAPEVLAQKP 197 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y A D WS GVI ++L+ GY PF D N L+++I KA +F P W S SAK I Sbjct: 198 YSKA-VDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256 Query: 1154 KKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDPAQLVVERR 1333 + +++ +PN R T + + W +TA +N +ES + Sbjct: 257 RNLMEKDPNKRYTCEQAARHPWIAG-------DTA------LNKNIHESVSAQIRKNFAK 303 Query: 1334 EERPAVMNAFELISTSQGLNLGTLFEKQTDSVKRETRFASR---LPANEILSKIEAAAGP 1504 + NA ++ + L+LG+ + SV AS+ L + + S I +++G Sbjct: 304 SKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFISSSSGV 363 Query: 1505 MGFNVQKRNYKLKLQGENPGRK 1570 G ++R + + G K Sbjct: 364 SGVGAERRPRPTTVTAVHSGSK 385
>P43291:ASK1_ARATH Serine/threonine-protein kinase ASK1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 363 Score = 199 bits (506), Expect = 3e-50 Identities = 114/281 (40%), Positives = 158/281 (56%), Gaps = 12/281 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YEL + +G G F + + + E VA+K +++ K+ + REI + +RHPN Sbjct: 4 YELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGP----KIDENVAREIINHRSLRHPN 59 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV+ + T + I ME GGELF++I S GR ED+AR +FQQLI+ V YCH+ + Sbjct: 60 IIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQI 119 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + LK+ DFG S + LLH +T GTP Y+APEV++ Sbjct: 120 CHRDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSRPKSTVGTPAYIAPEVLS 172 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTS 1138 + YDG AD+WSCGV L+V++ G PFED N +KI + P + S Sbjct: 173 RREYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHISQD 232 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAE 1261 K L+ +I N RITIAE+ + WF K ETA+ Sbjct: 233 CKNLLSRIFVANSLKRITIAEIKKHSWFLKNLPRELTETAQ 273
>Q7Y0B9:SAPK8_ORYSJ Serine/threonine-protein kinase SAPK8 - Oryza sativa subsp. japonica| (Rice) Length = 371 Score = 199 bits (505), Expect = 4e-50 Identities = 118/299 (39%), Positives = 167/299 (55%), Gaps = 12/299 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YEL R +G G F + R+ T E VA+K +++ + K+ ++REI + ++HPN Sbjct: 33 YELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGE----KIDDNVQREIINHRSLKHPN 88 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV+ + T + IVME +GGELF++I R ED+AR +FQQLI+ V YCHS V Sbjct: 89 IIRFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYCHSMQV 148 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + LK+ DFG S + +LH +T GTP Y+APEV+ Sbjct: 149 CHRDLKLENTLLDGSPAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLL 201 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPS--WFSTS 1138 K YDG AD+WSCGV L+V++ G PFED N ++I +S P S Sbjct: 202 KKEYDGKTADVWSCGVTLYVMVVGAYPFEDPEEPKNFRKTIQRILNVQYSIPENVDISPE 261 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDPAQ 1315 + LI +I +P+ RITI E+ ++ WF K + D ++S + E P Q Sbjct: 262 CRHLISRIFVGDPSLRITIPEIRSHGWFLKNLPADLMDD-----DSMSSQYEEPDQPMQ 315
>Q8IY84:NIM1_HUMAN Serine/threonine-protein kinase NIM1 - Homo sapiens (Human)| Length = 436 Score = 198 bits (503), Expect = 8e-50 Identities = 102/271 (37%), Positives = 162/271 (59%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y + +G G F++VK + T E VAIKILDK K L K + REIS+M+ + HPN Sbjct: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTK-LDQKTQRLLSREISSMEKLHHPN 132 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR+YEV+ + +K+++VME GGELF KI++ G+L E +++ F Q+++AV + H + Sbjct: 133 IIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQI 192 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK EN+ +N +KV DFG S +S ++ +L+T CG+P Y APE+ ++ Y G Sbjct: 193 IHRDLKAENVFYTSNTCVKVGDFGFSTVS---KKGEMLNTFCGSPPYAAPELFRDEHYIG 249 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 D+W+ GV+L+ ++ G +PF + L K I + +S P S +LI+ +L Sbjct: 250 IYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQI 309 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFETAEVN 1267 P R I ++N+EW + P E +++ Sbjct: 310 PTERYGIDCIMNDEWMQGVPYPTPLEPFQLD 340
>P07334:CDR1_SCHPO Mitosis inducer protein kinase cdr1 - Schizosaccharomyces pombe| (Fission yeast) Length = 593 Score = 197 bits (502), Expect = 1e-49 Identities = 103/254 (40%), Positives = 157/254 (61%), Gaps = 1/254 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 + LG+TLG G+ + V+ A++ +TG+ AIKI+ A I EI M+L+RHPN Sbjct: 12 WRLGKTLGTGSTSCVRLAKHAKTGDLAAIKIIPI-------RYASIGMEILMMRLLRHPN 64 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y+V +Y+ +E V GELF I G L E +A Y Q+++AV +CH Sbjct: 65 ILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCHRFRF 124 Query: 815 YHRDLKPENLLLDANGT-LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 991 HRDLK EN+L+ N +K++DFG++ + D L CG+ +Y+APE++++K Y Sbjct: 125 RHRDLKLENILIKVNEQQIKIADFGMATVEPN---DSCLENYCGSLHYLAPEIVSHKPYR 181 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 GA AD+WSCGVIL+ L++ LPF N +Y KI + PS S++A+ L+ ++LD Sbjct: 182 GAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPSSISSAAQDLLHRMLDV 241 Query: 1172 NPNTRITIAEVINN 1213 NP+TRITI EV ++ Sbjct: 242 NPSTRITIPEVFSH 255
>O14757:CHK1_HUMAN Serine/threonine-protein kinase Chk1 - Homo sapiens (Human)| Length = 476 Score = 197 bits (501), Expect = 1e-49 Identities = 143/467 (30%), Positives = 223/467 (47%), Gaps = 49/467 (10%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 ++L +TLGEG + +V+ A N T E VA+KI+D + + IK+EI K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP--ENIKKEICINKMLNHEN 66 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V++ Y Y+ +E +GGELFD+I + E DA+++F QL+ V Y H G+ Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGI 126 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLLD LK+SDFGL+ + + + LL+ CGT YVAPE++ + + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHA 186 Query: 995 AKADLWSCGVILFVLMAGYLPFED-SNLMALYKKIYKADFSCPSW--FSTSAKKLIKKIL 1165 D+WSCG++L ++AG LP++ S+ Y + W ++ L+ KIL Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246 Query: 1166 DPNPNTRITIAEVINNEWF----KKGYQPPRFETAEV-------------NLD--DINSI 1288 NP+ RITI ++ + W+ KKG + PR + V NLD +NS Sbjct: 247 VENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDFSPVNSA 306 Query: 1289 FNESGDPAQLVVERREERPAVMNAFELISTS--------QGLN----------------L 1396 +E V+ +P L TS QG++ L Sbjct: 307 SSEEN------VKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 360 Query: 1397 GTLFEKQTD---SVKRETRFASRLPANEILSKIEAAAGPMGFNVQKRNYKLKLQGENPGR 1567 GT Q VKR TRF ++L A++ ++ +G+ +K R Sbjct: 361 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 420 Query: 1568 KGQLAIATEVFEVTPSLYMVELRKSNGDTLEFHKFYHSISNGLKDVM 1708 +L + E+ + +V+ R S GD LEF + + I L D++ Sbjct: 421 NNKLIFKVNLLEMDDKI-LVDFRLSKGDGLEFKRHFLKIKGKLIDIV 466
>Q61241:TSSK1_MOUSE Testis-specific serine/threonine-protein kinase 1 - Mus musculus| (Mouse) Length = 364 Score = 196 bits (499), Expect = 2e-49 Identities = 108/261 (41%), Positives = 161/261 (61%), Gaps = 6/261 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y +G LGEG++AKVK A + NVA+KI+D+ K + + REI + ++ H + Sbjct: 12 YIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPSDFLEKFLPREIEILAMLNHRS 71 Query: 635 VIRMYEVMA-SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 +++ YE+ A S K+YIVMEL G+L + I +RG L+EDDARK F QL +A+ YCH Sbjct: 72 IVKTYEIFATSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDLD 131 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDG----LLHTTCGTPNYVAPEVINN 979 V HRDLK ENLLLD + +K+SDFG S + +R+D L T CG+ Y APEV+ Sbjct: 132 VVHRDLKSENLLLDKDFNIKLSDFGFS--KRCLRDDSGRLILSKTFCGSAAYAAPEVLQG 189 Query: 980 KGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMAL-YKKIYKADFSCPSWFSTSAKKLIK 1156 Y D+WS GVIL++++ G +P++DSN+ L +K ++ +F + K LI Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKLRIQKEHRVNFPRSKHLTGECKDLIY 249 Query: 1157 KILDPNPNTRITIAEVINNEW 1219 ++L P+ N R+ I E++N+ W Sbjct: 250 RMLQPDVNRRLHIDEILNHCW 270
>Q8BW96:KCC1D_MOUSE Calcium/calmodulin-dependent protein kinase type 1D - Mus musculus| (Mouse) Length = 385 Score = 196 bits (497), Expect = 4e-49 Identities = 125/368 (33%), Positives = 194/368 (52%), Gaps = 10/368 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E TLG G F++V A TG+ A+K + K K LK K + I+ EI+ ++ I+H N Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPK-KALKGKE-SSIENEIAVLRKIKHEN 80 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + ++ S +Y+VM+LV+GGELFD+I +G E DA +Q+++AV Y H G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 815 YHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLL D + +SDFGLS + + ++ T CGTP YVAPEV+ K Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSKME---GKGDVMSTACGTPGYVAPEVLAQKP 197 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y A D WS GVI ++L+ GY PF D N L+++I KA +F P W S SAK I Sbjct: 198 YSKA-VDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256 Query: 1154 KKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDPAQLVVERR 1333 + +++ +PN R T + + W +TA ++ +ES + Sbjct: 257 RNLMEKDPNKRYTCEQAARHPWIAG-------DTA------LSKNIHESVSAQIRKNFAK 303 Query: 1334 EERPAVMNAFELISTSQGLNLGTLFEKQTDSVKRETRFASR---LPANEILSKIEAAAGP 1504 + NA ++ + L LG+ + SV AS+ L + + S + +++G Sbjct: 304 SKWRQAFNATAVVRHMRRLQLGSSLDSSNASVSSNLSLASQKDCLAPSTLCSFLSSSSGV 363 Query: 1505 MGFNVQKR 1528 G ++R Sbjct: 364 AGVGAERR 371
>Q7XKA8:SAPK5_ORYSJ Serine/threonine-protein kinase SAPK5 - Oryza sativa subsp. japonica| (Rice) Length = 370 Score = 195 bits (495), Expect = 6e-49 Identities = 109/270 (40%), Positives = 154/270 (57%), Gaps = 12/270 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE R +G G F K RN ET E VA+K +++ +++ + REI + +RHPN Sbjct: 4 YEPVREIGAGNFGVAKLMRNKETRELVAMKFIERG----NRIDENVFREIVNHRSLRHPN 59 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR EV+ + + IVME GGELF++I GR ED+AR +FQQL+ V YCH+ + Sbjct: 60 IIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHAMQI 119 Query: 815 YHRDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVIN 976 HRDLK EN LLD + LK+ DFG S + LLH +T GTP Y+APEV++ Sbjct: 120 CHRDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSRPKSTVGTPAYIAPEVLS 172 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSWFSTS-- 1138 + YDG AD+WSCGV L+V++ G PFED N +I + P + S Sbjct: 173 RREYDGKLADVWSCGVTLYVMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYVHVSQP 232 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFKK 1228 + L+ +I NP RI++ E+ ++ WF K Sbjct: 233 CRHLLSRIFVANPYKRISMGEIKSHPWFLK 262
>Q6PGN3:DCLK2_MOUSE Serine/threonine-protein kinase DCLK2 - Mus musculus (Mouse)| Length = 756 Score = 194 bits (492), Expect = 1e-48 Identities = 106/265 (40%), Positives = 159/265 (60%), Gaps = 10/265 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y +G+ +G+G FA VK + TG+ A+KI+DK K + + I+ E+S ++ ++HPN Sbjct: 393 YRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHL--IENEVSILRRVKHPN 450 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I + E M + T +++VMELV GG+LFD I S + E D L NA+ Y HS + Sbjct: 451 IIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSI 510 Query: 815 YHRDLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 HRD+KPENLL+ D +LK+ DFGL+ + +G L+T CGTP YVAPE+I Sbjct: 511 VHRDIKPENLLVCEYPDGTKSLKLGDFGLATV-----VEGPLYTVCGTPTYVAPEIIAET 565 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMA--LYKKIY--KADFSCPSW--FSTSAK 1144 GY G K D+W+ GVI ++L+ G+ PF N + L+ +I K +F P W + SAK Sbjct: 566 GY-GLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAK 624 Query: 1145 KLIKKILDPNPNTRITIAEVINNEW 1219 +LI ++L N R T E++++ W Sbjct: 625 ELISQMLQVNVEARCTAGEILSHPW 649
>Q03002:YP141_YEAST Putative serine/threonine-protein kinase YPL141C - Saccharomyces| cerevisiae (Baker's yeast) Length = 865 Score = 193 bits (491), Expect = 2e-48 Identities = 108/276 (39%), Positives = 164/276 (59%), Gaps = 19/276 (6%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFA--RNVETGEN--------VAIKILDKDKVLK-HKMIAQIKRE 601 Y LG TLGEG F KVK +N N VAIK++ +D + ++ +I RE Sbjct: 41 YILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYRE 100 Query: 602 ISTMKLIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLI 781 I+ +K + HPN++++ EV+ + I IV+E GGE + I + RLKE +A + F QLI Sbjct: 101 INALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLI 160 Query: 782 NAVDYCHSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVA 961 + V Y HS+G+ HRDLK ENLLLD N L ++DFG +++ + L+ T+CG+P Y A Sbjct: 161 SGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGF--VNEFCSRNELMKTSCGSPCYAA 218 Query: 962 PE-VINNKGYDGAKADLWSCGVILFVLMAGYLPFED-------SNLMALYKKIYKADFSC 1117 PE VI+ + Y+ KAD+WSCGVIL+ ++AGYLP++D S++ LY I Sbjct: 219 PELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKF 278 Query: 1118 PSWFSTSAKKLIKKILDPNPNTRITIAEVINNEWFK 1225 P + + L++++L +P RI + ++ +EW K Sbjct: 279 PDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLK 314
>Q8N568:DCLK2_HUMAN Serine/threonine-protein kinase DCLK2 - Homo sapiens (Human)| Length = 766 Score = 193 bits (491), Expect = 2e-48 Identities = 104/265 (39%), Positives = 160/265 (60%), Gaps = 10/265 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++G+ +G+G FA VK + TG+ A+KI+DK K + + I+ E+S ++ ++HPN Sbjct: 394 YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHL--IENEVSILRRVKHPN 451 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I + E M + T++++VMELV GG+LFD I S + E D L NA+ Y H + Sbjct: 452 IIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSI 511 Query: 815 YHRDLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 HRD+KPENLL+ D +LK+ DFGL+ + +G L+T CGTP YVAPE+I Sbjct: 512 VHRDIKPENLLVCEYPDGTKSLKLGDFGLATV-----VEGPLYTVCGTPTYVAPEIIAET 566 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMA--LYKKIY--KADFSCPSW--FSTSAK 1144 GY G K D+W+ GVI ++L+ G+ PF N + L+ +I K +F P W + SAK Sbjct: 567 GY-GLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAK 625 Query: 1145 KLIKKILDPNPNTRITIAEVINNEW 1219 +LI ++L N R T +++++ W Sbjct: 626 ELISQMLQVNVEARCTAGQILSHPW 650
>Q91820:STK6_XENLA Serine/threonine-protein kinase 6 - Xenopus laevis (African clawed| frog) Length = 407 Score = 192 bits (489), Expect = 3e-48 Identities = 97/261 (37%), Positives = 152/261 (58%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR E+ +A+K+L K ++ K + Q++RE+ +RHPN Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPN 199 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y +++Y++++ GGELF ++ R + + Y +QL A+ YCHS+ V Sbjct: 200 ILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHSKKV 259 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL +NG LK++DFG S + R T CGT +Y+ PE+I + +D Sbjct: 260 IHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD- 314 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 DLWS GV+ + + G PFE Y++I K +F P + S A+ L+ K+L N Sbjct: 315 ETVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEARDLVSKLLKHN 374 Query: 1175 PNTRITIAEVINNEWFKKGYQ 1237 PN R+ + V+ + W K Q Sbjct: 375 PNHRLPLKGVLEHPWIIKNSQ 395
>Q91ZN7:CHK1_RAT Serine/threonine-protein kinase Chk1 - Rattus norvegicus (Rat)| Length = 476 Score = 192 bits (488), Expect = 4e-48 Identities = 142/467 (30%), Positives = 221/467 (47%), Gaps = 49/467 (10%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 ++L +TLGEG + +V+ A N T E VA+KI+D + + IK+EI K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCP--ENIKKEICINKMLNHEN 66 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V++ Y Y+ +E +GGELFD+I + E DA+++F QL+ V Y H G+ Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGI 126 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLLD LK+SDFGL+ + + + LL+ CGT YVAPE++ K + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHA 186 Query: 995 AKADLWSCGVILFVLMAGYLPFED-SNLMALYKKIYKADFSCPSW--FSTSAKKLIKKIL 1165 D+WSCG++L ++AG LP++ S+ Y + W ++ L+ KIL Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246 Query: 1166 DPNPNTRITIAEVINNEWFKK----GYQPPRFETAEV-------------NLD--DINSI 1288 NP+ RITI ++ + W+ K G + PR + + NLD INS Sbjct: 247 VENPSARITIPDIKKDRWYNKPLNRGAKRPRATSGGMSESSSGFSKHIHSNLDFSPINSG 306 Query: 1289 FNESGDPAQLVVERREERPAVMNAFELISTS--------QGLN----------------L 1396 +E V+ +P L T QG++ L Sbjct: 307 SSEEN------VKFSSSQPEPRTGLSLWDTGPSNVDKLVQGISFSQPTCPDHMLVNSQLL 360 Query: 1397 GTLFEKQTD---SVKRETRFASRLPANEILSKIEAAAGPMGFNVQKRNYKLKLQGENPGR 1567 GT Q VKR TRF ++L A++ ++ +G+ +K R Sbjct: 361 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETFEKLGYQWKKSCMNQVTVSTMDRR 420 Query: 1568 KGQLAIATEVFEVTPSLYMVELRKSNGDTLEFHKFYHSISNGLKDVM 1708 +L + E+ + +V+ R S GD LEF + + I L D++ Sbjct: 421 NNKLIFKINLVEMDEKI-LVDFRLSKGDGLEFKRHFLKIKGKLSDIV 466
>P25323:MYLK_DICDI Myosin light chain kinase - Dictyostelium discoideum (Slime mold)| Length = 295 Score = 192 bits (487), Expect = 5e-48 Identities = 103/277 (37%), Positives = 160/277 (57%), Gaps = 7/277 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE LG G F+ V N +T + AIK+++K ++ K +K E+ +K + HPN Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYE-KNLKMEVDILKKVNHPN 66 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I + E+ + K+Y+VMELVTGGELFDKI +G E DA +++++AV Y H + Sbjct: 67 IIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNI 126 Query: 815 YHRDLKPENLLLDANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + + ++DFGLS + Q ++ T CGTP+YVAPEV+N G Sbjct: 127 VHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTL---VMQTACGTPSYVAPEVLNATG 183 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPS--W--FSTSAKKLI 1153 YD + D+WS GVI ++L+ G+ PF + ++++I +A++ P W S AK I Sbjct: 184 YD-KEVDMWSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFI 242 Query: 1154 KKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEV 1264 K+L + + R+ +N+ W K +T ++ Sbjct: 243 GKLLVVDVSKRLNATNALNHPWLKSNNSNNTIDTVKM 279
>Q8AYC9:CHK1_CHICK Serine/threonine-protein kinase Chk1 - Gallus gallus (Chicken)| Length = 476 Score = 192 bits (487), Expect = 5e-48 Identities = 143/465 (30%), Positives = 218/465 (46%), Gaps = 47/465 (10%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 ++L +TLGEG + +V+ A N T E VA+KI+D + IK+EI K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAADCP--ENIKKEICINKMLNHEN 66 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V++ Y Y+ +E +GGELFD+I + E +A+++FQQLI V Y HS G+ Sbjct: 67 VVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHSMGI 126 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLLLD LK+SDFGL+ + + + LL+ CGT YVAPE++ + Sbjct: 127 THRDLKPENLLLDERDNLKISDFGLATVFKHNGRERLLNKMCGTLPYVAPELLRRPEFRA 186 Query: 995 AKADLWSCGVILFVLMAGYLPFED-SNLMALYKKIYKADFSCPSW--FSTSAKKLIKKIL 1165 D+W+CGV+L ++AG LP++ S+ Y + W ++ L+ KIL Sbjct: 187 EPVDVWACGVVLTAMLAGELPWDQPSDSCQEYSDWKERKTYLAPWRKIDSAPLALLHKIL 246 Query: 1166 DPNPNTRITIAEVINNEWF----KKGYQP---------------PRFETAEVNLDDINSI 1288 NP RITI ++ + W+ KKG + P+ ++ + + S Sbjct: 247 TENPTARITIPDIKKDRWYCRPLKKGTKRGRVSSGGVTESPGALPKHIRSDTDFSPVKSA 306 Query: 1289 FNESGDPAQLVVERREERPAVMNAFELISTS------QGLN----------------LGT 1402 E D A + E P A ST QG++ LGT Sbjct: 307 LGE--DKASYSTSQPE--PGTGGALWDSSTGSIDRLVQGISFSQPACPEHMLLNSQLLGT 362 Query: 1403 LFEKQTD---SVKRETRFASRLPANEILSKIEAAAGPMGFNVQKRNYKLKLQGENPGRKG 1573 Q+ V+R TRF ++L A+ + MG+ ++ R Sbjct: 363 PGSSQSPWQRLVRRMTRFFTKLDADGSYRSLRDVCEKMGYGWKQSCTNQVTISTTDRRNN 422 Query: 1574 QLAIATEVFEVTPSLYMVELRKSNGDTLEFHKFYHSISNGLKDVM 1708 +L + E+ S +V+ R S GD LEF + + I L DV+ Sbjct: 423 KLIFKVNLLEM-ESRILVDFRLSKGDGLEFKRHFLKIKGKLSDVV 466
>P97477:STK6_MOUSE Serine/threonine-protein kinase 6 - Mus musculus (Mouse)| Length = 395 Score = 191 bits (486), Expect = 7e-48 Identities = 95/270 (35%), Positives = 158/270 (58%), Gaps = 1/270 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +++GR LG+G F V AR ++ +A+K+L K ++ K + Q++RE+ +RHPN Sbjct: 124 FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPN 183 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y T++Y+++E G ++ ++ + E Y +L NA+ YCHS+ V Sbjct: 184 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 243 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL +NG LK++DFG S + R T CGT +Y+ PE+I + +D Sbjct: 244 IHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TMCGTLDYLPPEMIEGRMHD- 298 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLWS GV+ + + G PFE Y++I + +F+ P + + A+ LI ++L N Sbjct: 299 EKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHN 358 Query: 1175 PNTRITIAEVINNEWFK-KGYQPPRFETAE 1261 + R+T+AEV+ + W K +PP T++ Sbjct: 359 ASQRLTLAEVLEHPWIKANSSKPPTGHTSK 388
>O64629:AUR3_ARATH Serine/threonine-protein kinase Aurora-3 - Arabidopsis thaliana| (Mouse-ear cress) Length = 288 Score = 191 bits (486), Expect = 7e-48 Identities = 97/264 (36%), Positives = 156/264 (59%), Gaps = 2/264 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F +V AR ++ VA+K++ K+++ K+K+ Q++RE+ +RHPN Sbjct: 22 FEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQLRREMEIQTSLRHPN 81 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R++ +I++++E GGEL+ + G L E A Y L A+ YCH + V Sbjct: 82 ILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCHGKCV 141 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLLD G LK++DFG S S R+ T CGT +Y+APE++ N+ +D Sbjct: 142 IHRDIKPENLLLDHEGRLKIADFGWSVQSSNKRK-----TMCGTLDYLAPEMVENRDHDY 196 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSW--FSTSAKKLIKKILD 1168 A D W+ G++ + + G PFE + +K+I K D S P S AK LI ++L Sbjct: 197 A-VDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAKNLISQLLV 255 Query: 1169 PNPNTRITIAEVINNEWFKKGYQP 1240 +P+ R++I +++ + W K P Sbjct: 256 KDPSKRLSIEKIMQHPWIVKNADP 279
>Q9JLM8:DCLK1_MOUSE Serine/threonine-protein kinase DCLK1 - Mus musculus (Mouse)| Length = 756 Score = 191 bits (484), Expect = 1e-47 Identities = 124/370 (33%), Positives = 190/370 (51%), Gaps = 10/370 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++GRT+G+G FA VK T A+KI+ K K + + I+ E+S ++ ++HPN Sbjct: 406 YKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHM--IQNEVSILRRVKHPN 463 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + E M T++Y+VMELV GG+LFD I S + E DA L +A+ Y HS + Sbjct: 464 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNI 523 Query: 815 YHRDLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 HRD+KPENLL+ D + +LK+ DFGL+ + DG L+T CGTP YVAPE+I Sbjct: 524 VHRDIKPENLLVYEHQDGSKSLKLGDFGLATI-----VDGPLYTVCGTPTYVAPEIIAET 578 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDS--NLMALYKKIY--KADFSCPSW--FSTSAK 1144 GY G K D+W+ GVI ++L+ G+ PF S + L+ +I + DF P W S SAK Sbjct: 579 GY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAK 637 Query: 1145 KLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDPAQLVV 1324 +LI +L N + R + +V+ + W P V I FN P+ Sbjct: 638 ELINMMLLVNVDQRFSAVQVLEHPWVNDDGLPENEHQLSV-AGKIKKHFNTGPKPS---- 692 Query: 1325 ERREERPAVMNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAAAGP 1504 ST+ G+++ T ++ +E + R ++ S+ +A P Sbjct: 693 ----------------STAAGVSV-----IATTALDKERQVFRRRRNQDVRSRYKAQPAP 731 Query: 1505 MGFNVQKRNY 1534 N + +Y Sbjct: 732 PELNSESEDY 741
>O59790:ARK1_SCHPO Serine/threonine-protein kinase ark1 - Schizosaccharomyces pombe| (Fission yeast) Length = 355 Score = 191 bits (484), Expect = 1e-47 Identities = 98/259 (37%), Positives = 152/259 (58%), Gaps = 1/259 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+G+ LG+G F +V A+ +TG VA+K L K ++++ K+ Q++REI +RH N Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y +IY+++E GEL+ + R E+ A KY Q+ NA+ Y H + V Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 208 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPEN+LL +G +K+SDFG S + R T CGT +Y+ PE++ K + Sbjct: 209 IHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRT----TLCGTLDYLPPEMVEGKEHT- 263 Query: 995 AKADLWSCGVILFVLMAGYLPFED-SNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 K DLWS GV+ + + G PFED S A YK+I K D PS+ A+ LI ++L Sbjct: 264 EKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLISRLLQH 323 Query: 1172 NPNTRITIAEVINNEWFKK 1228 NP R+++ +V+ + W K Sbjct: 324 NPEKRMSLEQVMRHPWIVK 342
>O70150:KCC1B_RAT Calcium/calmodulin-dependent protein kinase type 1B - Rattus| norvegicus (Rat) Length = 343 Score = 190 bits (483), Expect = 2e-47 Identities = 107/262 (40%), Positives = 156/262 (59%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+ LG G F++V A+ + VA+K + K K L+ K A ++ EI+ ++ I HPN Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPK-KALRGKE-ALVENEIAVLRRISHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + +V S + +Y+ MELVTGGELFD+I RG E DA Q++ AV Y HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLL + + VSDFGLS +++ +L T CGTP YVAPE++ K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLS----KIQAGNMLGTACGTPGYVAPELLEQKP 188 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+ GVI ++L+ GY PF D + L+ +I +A +F P W S SAK I Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 + +L+ +P R T + + + W Sbjct: 248 RHLLERDPQKRFTCQQALQHLW 269
>Q9QYK9:KCC1B_MOUSE Calcium/calmodulin-dependent protein kinase type 1B - Mus musculus| (Mouse) Length = 343 Score = 190 bits (483), Expect = 2e-47 Identities = 107/262 (40%), Positives = 156/262 (59%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+ LG G F++V A+ + VA+K + K K L+ K A ++ EI+ ++ I HPN Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPK-KALRGKE-ALVENEIAVLRRISHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + +V S + +Y+ MELVTGGELFD+I RG E DA Q++ AV Y HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLL + + VSDFGLS +++ +L T CGTP YVAPE++ K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLS----KIQAGNMLGTACGTPGYVAPELLEQKP 188 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+ GVI ++L+ GY PF D + L+ +I +A +F P W S SAK I Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 + +L+ +P R T + + + W Sbjct: 248 RHLLERDPQKRFTCQQALQHLW 269
>O08875:DCLK1_RAT Serine/threonine-protein kinase DCLK1 - Rattus norvegicus (Rat)| Length = 433 Score = 190 bits (483), Expect = 2e-47 Identities = 107/265 (40%), Positives = 158/265 (59%), Gaps = 10/265 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++GRT+G+G FA VK T A+KI+ K K + + I+ E+S ++ ++HPN Sbjct: 83 YKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHM--IQNEVSILRRVKHPN 140 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + E M T++Y+VMELV GG+LFD I S + E DA L +A+ Y HS + Sbjct: 141 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNI 200 Query: 815 YHRDLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 HRD+KPENLL+ D + +LK+ DFGL+ + DG L+T CGTP YVAPE+I Sbjct: 201 VHRDIKPENLLVYEHQDGSKSLKLGDFGLATI-----VDGPLYTVCGTPTYVAPEIIAET 255 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDS--NLMALYKKIY--KADFSCPSW--FSTSAK 1144 GY G K D+W+ GVI ++L+ G+ PF S + L+ +I + DF P W S SAK Sbjct: 256 GY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAK 314 Query: 1145 KLIKKILDPNPNTRITIAEVINNEW 1219 +LI +L N + R + +V+ + W Sbjct: 315 ELINMMLLVNVDQRFSAVQVLEHPW 339
>O35280:CHK1_MOUSE Serine/threonine-protein kinase Chk1 - Mus musculus (Mouse)| Length = 476 Score = 190 bits (483), Expect = 2e-47 Identities = 137/463 (29%), Positives = 221/463 (47%), Gaps = 45/463 (9%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 ++L +TLGEG + +V+ A N T E VA+KI+D + + IK+EI K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCP--ENIKKEICINKMLSHEN 66 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V++ Y Y+ +E +GGELFD+I + E DA+++F QL+ V Y H G+ Sbjct: 67 VVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGI 126 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLLD LK+SDFGL+ + + + LL+ CGT YVAPE++ K + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHA 186 Query: 995 AKADLWSCGVILFVLMAGYLPFED-SNLMALYKKIYKADFSCPSW--FSTSAKKLIKKIL 1165 D+WSCG++L ++AG LP++ S+ Y + W ++ L+ KIL Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246 Query: 1166 DPNPNTRITIAEVINNEWFKK----GYQPPRFETAEVNLDDINSIFNE-----------S 1300 P+ RITI ++ + W+ K G + PR + + + +S F++ + Sbjct: 247 VETPSARITIPDIKKDRWYNKPLNRGAKRPRATSG--GMSESSSGFSKHIHSNLDFSPVN 304 Query: 1301 GDPAQLVVERREERPAVMNAFELISTS--------QGLN----------------LGTLF 1408 ++ V+ +P L T QG++ LGT Sbjct: 305 NGSSEETVKFSSSQPEPRTGLSLWDTGPSNVDKLVQGISFSQPTCPEHMLVNSQLLGTPG 364 Query: 1409 EKQTD---SVKRETRFASRLPANEILSKIEAAAGPMGFNVQKRNYKLKLQGENPGRKGQL 1579 Q VKR TRF ++L A++ ++ +G+ +K R +L Sbjct: 365 SSQNPWQRLVKRMTRFFTKLDADKSYQCLKETFEKLGYQWKKSCMNQVTVSTTDRRNNKL 424 Query: 1580 AIATEVFEVTPSLYMVELRKSNGDTLEFHKFYHSISNGLKDVM 1708 + E+ + +V+ R S GD LEF + + I L DV+ Sbjct: 425 IFKINLVEMDEKI-LVDFRLSKGDGLEFKRHFLKIKGKLSDVV 466
>Q9BXA7:TSSK1_HUMAN Testis-specific serine/threonine-protein kinase 1 - Homo sapiens| (Human) Length = 367 Score = 190 bits (482), Expect = 2e-47 Identities = 107/264 (40%), Positives = 158/264 (59%), Gaps = 7/264 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG LGEG++AKVK A + NVAIKI+D+ K + + REI + ++ H + Sbjct: 12 YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCS 71 Query: 635 VIRMYEVM-ASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 +I+ YE+ S K+YIVMEL G+L + I +RG L ED+ARK F QL A+ YCH Sbjct: 72 IIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLSALSQQVRED----GLLHTTCGTPNYVAPEVINN 979 V HRDLK +NLLLD + +K+SDF S + +R+D L T CG+P Y APEV+ Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFS--KRCLRDDSGRMALSKTFCGSPAYAAPEVLQG 189 Query: 980 KGYDGAKADLWSCGVILFVLMAGYLPFEDSNL--MALYKKIYKADFSCPSWFSTSAKKLI 1153 Y D+WS GVIL++++ G +P++DSN+ M +K ++ +F + K LI Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEWFK 1225 +L P+ N R+ I E++++ W + Sbjct: 250 YHMLQPDVNRRLHIDEILSHCWMQ 273
>Q6P2M8:KCC1B_HUMAN Calcium/calmodulin-dependent protein kinase type 1B - Homo sapiens| (Human) Length = 343 Score = 190 bits (482), Expect = 2e-47 Identities = 107/262 (40%), Positives = 156/262 (59%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+ LG G F++V A+ + VA+K + K K L+ K A ++ EI+ ++ I HPN Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPK-KALRGKE-ALVENEIAVLRRISHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + +V S + +Y+ MELVTGGELFD+I RG E DA Q++ AV Y HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLL + + VSDFGLS +++ +L T CGTP YVAPE++ K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLS----KIQAGNMLGTACGTPGYVAPELLEQKP 188 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+ GVI ++L+ GY PF D + L+ +I +A +F P W S SAK I Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 + +L+ +P R T + + + W Sbjct: 248 RHLLERDPQKRFTCQQALRHLW 269
>Q63450:KCC1A_RAT Calcium/calmodulin-dependent protein kinase type 1 - Rattus| norvegicus (Rat) Length = 374 Score = 190 bits (482), Expect = 2e-47 Identities = 106/262 (40%), Positives = 156/262 (59%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+ LG G F++V A + T + VAIK + K K L+ K ++ EI+ + I+HPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAK-KALEGKE-GSMENEIAVLHKIKHPN 77 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + ++ S +Y++M+LV+GGELFD+I +G E DA + Q+++AV Y H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 815 YHRDLKPENLL---LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLL LD + + +SDFGLS + +L T CGTP YVAPEV+ K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKP 194 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y A D WS GVI ++L+ GY PF D N L+++I KA +F P W S SAK I Sbjct: 195 YSKA-VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 + +++ +P R T + + + W Sbjct: 254 RHLMEKDPEKRFTCEQALQHPW 275
>Q91YS8:KCC1A_MOUSE Calcium/calmodulin-dependent protein kinase type 1 - Mus musculus| (Mouse) Length = 374 Score = 190 bits (482), Expect = 2e-47 Identities = 106/262 (40%), Positives = 156/262 (59%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+ LG G F++V A + T + VAIK + K K L+ K ++ EI+ + I+HPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAK-KALEGKE-GSMENEIAVLHKIKHPN 77 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + ++ S +Y++M+LV+GGELFD+I +G E DA + Q+++AV Y H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 815 YHRDLKPENLL---LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLL LD + + +SDFGLS + +L T CGTP YVAPEV+ K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKP 194 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y A D WS GVI ++L+ GY PF D N L+++I KA +F P W S SAK I Sbjct: 195 YSKA-VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 + +++ +P R T + + + W Sbjct: 254 RHLMEKDPEKRFTCEQALQHPW 275
>O88445:AURKC_MOUSE Serine/threonine-protein kinase 13 - Mus musculus (Mouse)| Length = 282 Score = 190 bits (482), Expect = 2e-47 Identities = 96/258 (37%), Positives = 152/258 (58%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG G F +V AR E VA+K+L K ++ K + Q++RE+ ++H N Sbjct: 16 FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRN 75 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y T+IY+++E GGEL+ ++ +L + Q+L +A+ YCH + V Sbjct: 76 ILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKV 135 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL NG +K+SDFG S + +R T CGT +Y+ PE+I K Y+ Sbjct: 136 IHRDIKPENLLLGLNGEVKISDFGWSVHTPSLRR----KTMCGTLDYLPPEMIAQKPYN- 190 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 DLW GV+ + L+ G PFE S Y++I + DF PS A+ LI K+L + Sbjct: 191 EMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYH 250 Query: 1175 PNTRITIAEVINNEWFKK 1228 P+ R+++A+V+ + W ++ Sbjct: 251 PSERLSLAQVLKHPWVRE 268
>Q3SZW1:TSSK1_BOVIN Testis-specific serine/threonine-protein kinase 1 - Bos taurus| (Bovine) Length = 367 Score = 189 bits (481), Expect = 3e-47 Identities = 106/262 (40%), Positives = 159/262 (60%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y +G LGEG++AKVK A + NVA+KI+D+ K + + REI + ++ H + Sbjct: 12 YIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPTDFLEKFLPREIEILAMLNHRS 71 Query: 635 VIRMYEVM-ASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 +I+ YE+ S K+YIVMEL G+L + I +RG L+EDDARK F QL +A+ YCH Sbjct: 72 IIKTYEIFETSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDLD 131 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDG----LLHTTCGTPNYVAPEVINN 979 V HRDLK ENLLLD + +K+SDFG S + +R+D L T CG+ Y APEV+ Sbjct: 132 VVHRDLKCENLLLDKDFNIKLSDFGFS--KRCLRDDSGRLTLSKTFCGSAAYAAPEVLQG 189 Query: 980 KGYDGAKADLWSCGVILFVLMAGYLPFEDSNL--MALYKKIYKADFSCPSWFSTSAKKLI 1153 Y D+WS GVIL++++ G +P++DSN+ M +K ++ +F + K LI Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 ++L P+ R+ I E++++ W Sbjct: 250 YRMLQPDVTRRLHIDEILSHCW 271
>Q96NX5:KCC1G_HUMAN Calcium/calmodulin-dependent protein kinase type 1G - Homo sapiens| (Human) Length = 476 Score = 189 bits (481), Expect = 3e-47 Identities = 102/256 (39%), Positives = 152/256 (59%), Gaps = 7/256 (2%) Frame = +2 Query: 473 LGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRMYE 652 LG G F++V + TG+ A+K + K + + ++ EI+ +K I+H N++ + + Sbjct: 29 LGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRD---SSLENEIAVLKKIKHENIVTLED 85 Query: 653 VMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLK 832 + S T Y+VM+LV+GGELFD+I RG E DA QQ+++AV Y H G+ HRDLK Sbjct: 86 IYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLK 145 Query: 833 PENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 1003 PENLL + N + ++DFGLS + Q +G++ T CGTP YVAPEV+ K Y A Sbjct: 146 PENLLYLTPEENSKIMITDFGLSKMEQ----NGIMSTACGTPGYVAPEVLAQKPYSKA-V 200 Query: 1004 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILDP 1171 D WS GVI ++L+ GY PF + L++KI + +F P W S SAK I +L+ Sbjct: 201 DCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEK 260 Query: 1172 NPNTRITIAEVINNEW 1219 +PN R T + +++ W Sbjct: 261 DPNERYTCEKALSHPW 276
>Q7TNJ7:KCC1G_RAT Calcium/calmodulin-dependent protein kinase type 1G - Rattus| norvegicus (Rat) Length = 476 Score = 189 bits (480), Expect = 4e-47 Identities = 102/256 (39%), Positives = 151/256 (58%), Gaps = 7/256 (2%) Frame = +2 Query: 473 LGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRMYE 652 LG G F++V + TG+ A+K + K + + ++ EI+ +K I+H N++ + + Sbjct: 29 LGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRD---SSLENEIAVLKRIKHENIVTLED 85 Query: 653 VMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLK 832 + S T Y+VM+LV+GGELFD+I RG E DA QQ+++AV Y H G+ HRDLK Sbjct: 86 IYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLK 145 Query: 833 PENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 1003 PENLL + N + ++DFGLS + Q +G++ T CGTP YVAPEV+ K Y A Sbjct: 146 PENLLYLTPEENSKIMITDFGLSKMEQ----NGVMSTACGTPGYVAPEVLAQKPYSKA-V 200 Query: 1004 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILDP 1171 D WS GVI ++L+ GY PF + L++KI + +F P W S SAK I +L+ Sbjct: 201 DCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEK 260 Query: 1172 NPNTRITIAEVINNEW 1219 +PN R T + + + W Sbjct: 261 DPNERYTCEKALRHPW 276
>Q91VB2:KCC1G_MOUSE Calcium/calmodulin-dependent protein kinase type 1G - Mus musculus| (Mouse) Length = 477 Score = 189 bits (480), Expect = 4e-47 Identities = 102/256 (39%), Positives = 151/256 (58%), Gaps = 7/256 (2%) Frame = +2 Query: 473 LGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRMYE 652 LG G F++V + TG+ A+K + K + + ++ EI+ +K I+H N++ + + Sbjct: 29 LGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRD---SSLENEIAVLKRIKHENIVTLED 85 Query: 653 VMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLK 832 + S T Y+VM+LV+GGELFD+I RG E DA QQ+++AV Y H G+ HRDLK Sbjct: 86 IYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLK 145 Query: 833 PENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 1003 PENLL + N + ++DFGLS + Q +G++ T CGTP YVAPEV+ K Y A Sbjct: 146 PENLLYLTPEENSKIMITDFGLSKMEQ----NGVMSTACGTPGYVAPEVLAQKPYSKA-V 200 Query: 1004 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILDP 1171 D WS GVI ++L+ GY PF + L++KI + +F P W S SAK I +L+ Sbjct: 201 DCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEK 260 Query: 1172 NPNTRITIAEVINNEW 1219 +PN R T + + + W Sbjct: 261 DPNERYTCEKALRHPW 276
>P59241:STK6_RAT Serine/threonine-protein kinase 6 - Rattus norvegicus (Rat)| Length = 397 Score = 189 bits (479), Expect = 5e-47 Identities = 93/263 (35%), Positives = 152/263 (57%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +++GR LG+G F V AR ++ +A+K+L K ++ K + Q++RE+ +RHPN Sbjct: 126 FDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQLRREVEIQSHLRHPN 185 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y T++Y+++E G ++ ++ + E Y +L NA+ YCHS+ V Sbjct: 186 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 245 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL +NG LK++DFG S + R T CGT +Y PE+I + +D Sbjct: 246 IHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYQPPEMIEGRMHD- 300 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLWS GV+ + + G PFE Y++I + +F+ P + + A+ LI ++L N Sbjct: 301 EKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHN 360 Query: 1175 PNTRITIAEVINNEWFKKGYQPP 1243 + R+T+AEV+ + W K P Sbjct: 361 SSQRLTLAEVLEHPWIKANSSKP 383
>Q14012:KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 - Homo sapiens| (Human) Length = 370 Score = 189 bits (479), Expect = 5e-47 Identities = 103/262 (39%), Positives = 155/262 (59%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+ LG G F++V A + T + VAIK + K+ + + ++ EI+ + I+HPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKE--GSMENEIAVLHKIKHPN 77 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + ++ S +Y++M+LV+GGELFD+I +G E DA + Q+++AV Y H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 815 YHRDLKPENLL---LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLL LD + + +SDFGLS + +L T CGTP YVAPEV+ K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKP 194 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y A D WS GVI ++L+ GY PF D N L+++I KA +F P W S SAK I Sbjct: 195 YSKA-VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 + +++ +P R T + + + W Sbjct: 254 RHLMEKDPEKRFTCEQALQHPW 275
>Q501V0:KPSH1_DANRE Serine/threonine-protein kinase H1 homolog - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 422 Score = 188 bits (478), Expect = 6e-47 Identities = 99/263 (37%), Positives = 165/263 (62%), Gaps = 8/263 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQI-KREISTMKLIRHP 631 Y++ +G G+F++V + T + AIK+++ +++ ++ + E+ ++ +RH Sbjct: 96 YDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIET----RYREGREVCESELCVLRRVRHT 151 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 N+I++ EV + ++Y+VMEL TGGELFD+I +RG E DA + Q +++ V Y H+ G Sbjct: 152 NIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLG 211 Query: 812 VYHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 + HRDLKPENLL A+ + ++DFGL A +++ ++ L+ TTCGTP Y+APE++ K Sbjct: 212 ITHRDLKPENLLYYHPGADSKIMITDFGL-ASTRKKGDECLMKTTCGTPEYIAPEILVRK 270 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTS--AKKL 1150 Y A D+W+ GVI ++L++G +PFED N M LY++I K FS W S S AK Sbjct: 271 PYTNA-VDMWALGVISYILLSGTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDF 329 Query: 1151 IKKILDPNPNTRITIAEVINNEW 1219 I ++L +PN R++ + + + W Sbjct: 330 IDRVLTVDPNERLSAGQALKHPW 352
>O15075:DCLK1_HUMAN Serine/threonine-protein kinase DCLK1 - Homo sapiens (Human)| Length = 740 Score = 188 bits (477), Expect = 8e-47 Identities = 106/265 (40%), Positives = 158/265 (59%), Gaps = 10/265 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++GRT+G+G FA VK T A+KI+ K K + + I+ E+S ++ ++HPN Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM--IQNEVSILRRVKHPN 447 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + E M T++Y+VMELV GG+LFD I S + E DA L +A+ Y HS + Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507 Query: 815 YHRDLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 HRD+KPENLL+ D + +LK+ DFGL+ + DG L+T CGTP YVAPE+I Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLATI-----VDGPLYTVCGTPTYVAPEIIAET 562 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDS--NLMALYKKIY--KADFSCPSW--FSTSAK 1144 GY G K D+W+ GVI ++L+ G+ PF S + L+ +I + DF P W S SAK Sbjct: 563 GY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAK 621 Query: 1145 KLIKKILDPNPNTRITIAEVINNEW 1219 +LI +L + + R + +V+ + W Sbjct: 622 ELITMMLLVDVDQRFSAVQVLEHPW 646
>Q9HFF4:PPK1_SCHPO Serine/threonine-protein kinase ppk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1023 Score = 187 bits (474), Expect = 2e-46 Identities = 107/286 (37%), Positives = 166/286 (58%), Gaps = 29/286 (10%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGEN--------VAIKILDKDKVLKHKMIAQIKREIST 610 Y LGRT+G G F KVK + + V IKI+ K ++ +++ RE++ Sbjct: 492 YILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTK--QNCQTSRLMREVAI 549 Query: 611 MKLI--RHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLIN 784 +K + HP++++ + + ++ IV++ V GGELFD I +R RL++ A + F QLI+ Sbjct: 550 LKGLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLIS 609 Query: 785 AVDYCHSRGVYHRDLKPENLLLDANGTLKVSDFG----------LSALSQQVREDGLLHT 934 V Y HSRGV HRDLK EN+LLD N + ++DFG LS S + L T Sbjct: 610 GVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTFGHFNTLSEHSLPTEKPDLFST 669 Query: 935 TCGTPNYVAPEVINNKG--YDGAKADLWSCGVILFVLMAGYLPFED-------SNLMALY 1087 +CG+P Y APE++N K Y G +AD+WSCGVIL+ ++AGYLPF+D N+ LY Sbjct: 670 SCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPFDDDPHNPNGENVPRLY 729 Query: 1088 KKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRITIAEVINNEWFK 1225 + I P +F + A+ ++KKIL P+P R+ ++ ++N+ + + Sbjct: 730 RYICSTPLIFPEFFKSKARDILKKILVPDPAKRVRMSAIMNHAYLR 775
>Q755C4:IPL1_ASHGO Spindle assembly checkpoint kinase - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 367 Score = 186 bits (473), Expect = 2e-46 Identities = 86/258 (33%), Positives = 154/258 (59%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+G+ LG+G F +V R++E+G A+K ++K ++++ + Q +RE+ +RHPN Sbjct: 109 FEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLRHPN 168 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 + ++Y ++Y++ME + GEL+ + R + A Y Q+ +A+DY H R + Sbjct: 169 LTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALDYMHERNI 228 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPEN+++ N T+K++DFG S ++ + T CGT +Y++PE+I ++ Y+ Sbjct: 229 LHRDIKPENIIIGFNNTIKLTDFGWSVITP---KGSKRKTLCGTVDYLSPELIRSREYN- 284 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K D+W+ GV+ + L+ G PFE+ + YK+I K + P T A+ LI ++L+ + Sbjct: 285 EKVDVWALGVLTYELLVGSPPFEEESKELTYKRILKRNLIFPDHVDTEARHLISRLLEYD 344 Query: 1175 PNTRITIAEVINNEWFKK 1228 P RI + EV + W +K Sbjct: 345 PGDRIPLKEVKKHPWIEK 362
>Q6GPL3:AUKBB_XENLA Serine/threonine-protein kinase 12-B - Xenopus laevis (African clawed| frog) Length = 368 Score = 186 bits (473), Expect = 2e-46 Identities = 94/271 (34%), Positives = 154/271 (56%), Gaps = 3/271 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +++GR LG+G F V AR + +A+K+L K ++ K + Q++REI +RHPN Sbjct: 100 FDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPN 159 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++RMY R +IY+++E GEL+ ++ GR E + + ++L +A+ YCH R V Sbjct: 160 ILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALQYCHERKV 219 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLL+ G LK++DFG S + +R T CGT +Y+ PE+I K +D Sbjct: 220 IHRDIKPENLLMGYKGELKIADFGWSVHAPSLRR----RTMCGTLDYLPPEMIEGKTHD- 274 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLW GV+ + + G PF+ + +++I D P + S +K LI K+L + Sbjct: 275 EKVDLWCAGVLCYEFLVGMPPFDSPSHSETHRRIVNVDLKFPPFLSEGSKDLISKLLRYH 334 Query: 1175 PNTRITIAEVINNEWFKKGYQ---PPRFETA 1258 P R+ + V+ + W K + PP ++++ Sbjct: 335 PAQRLPLKGVMEHPWVKANSRRVLPPVYQSS 365
>Q6DE08:AUKBA_XENLA Serine/threonine-protein kinase 12-A - Xenopus laevis (African clawed| frog) Length = 361 Score = 186 bits (473), Expect = 2e-46 Identities = 94/272 (34%), Positives = 154/272 (56%), Gaps = 3/272 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +++GR LG+G F V AR + +A+K+L K ++ K + Q++REI +RHPN Sbjct: 93 FDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPN 152 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++RMY R +IY+++E GEL+ ++ GR E + + ++L +A+ YCH R V Sbjct: 153 ILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALHYCHERKV 212 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLL+ G LK++DFG S + +R T CGT +Y+ PE+I K +D Sbjct: 213 IHRDIKPENLLMGYKGELKIADFGWSVHAPSLRR----RTMCGTLDYLPPEMIEGKTHD- 267 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLW GV+ + + G PF+ + +++I D P + S +K LI K+L + Sbjct: 268 EKVDLWCAGVLCYEFLVGMPPFDSPSHTETHRRIVNVDLKFPPFLSDGSKDLISKLLRYH 327 Query: 1175 PNTRITIAEVINNEWFKKGYQ---PPRFETAE 1261 P R+ + V+ + W K + PP +++ + Sbjct: 328 PPQRLPLKGVMEHPWVKANSRRVLPPVYQSTQ 359
>Q6NW76:AURKB_DANRE Serine/threonine-protein kinase 12 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 320 Score = 186 bits (472), Expect = 3e-46 Identities = 91/257 (35%), Positives = 148/257 (57%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +++GR LG+G F V AR + +A+K+L K +++K + Q++REI +RHPN Sbjct: 53 FDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLRHPN 112 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R Y T++++++E GE++ ++ GR + Y +++ +A+ YCH + V Sbjct: 113 ILRFYNYFHDDTRVFLILEYAPRGEMYKELQRYGRFDDQRTATYMEEVSDALQYCHEKKV 172 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL G LK++DFG S + +R T CGT +Y+ PE+I +D Sbjct: 173 IHRDIKPENLLLGYRGELKIADFGWSVHAPSLRR----RTMCGTLDYLPPEMIEGHSHD- 227 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLWS GV+ + + G PFE ++ YK+I K D P S A+ LI K+L + Sbjct: 228 EKVDLWSIGVLCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHS 287 Query: 1175 PNTRITIAEVINNEWFK 1225 P+ R+ + V+ + W K Sbjct: 288 PSMRLPLRSVMEHPWVK 304
>Q924X7:STK33_MOUSE Serine/threonine-protein kinase 33 - Mus musculus (Mouse)| Length = 491 Score = 185 bits (470), Expect = 5e-46 Identities = 105/268 (39%), Positives = 158/268 (58%), Gaps = 13/268 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G+F V A + ETG AIK ++K+K M ++RE+S +K + H + Sbjct: 111 YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSSAM-KLLEREVSILKTVNHQH 169 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I + +V S K+Y+VMEL GEL + RG E++ R Q L +A+ Y H++ + Sbjct: 170 IIHLEQVFESPQKMYLVMELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKDI 229 Query: 815 YHRDLKPENLLL---------DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPE 967 HRDLK EN+++ + N +KV+DFGLS R +G++ TTCGTP Y+APE Sbjct: 230 VHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPE 289 Query: 968 VINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKAD--FSCPSW--FST 1135 VIN Y + D+WS GVI+F+L+ G PF ++ LY+ I K + F P W S Sbjct: 290 VINAHDY-SQQCDIWSIGVIMFILLCGEPPFLANSEEKLYELIKKGELRFENPVWESVSD 348 Query: 1136 SAKKLIKKILDPNPNTRITIAEVINNEW 1219 SAK +K+++ +P RIT E+++N+W Sbjct: 349 SAKNTLKQLMKVDPAHRITAKELLDNQW 376
>Q5ZKI0:KCC2D_CHICK Calcium/calmodulin-dependent protein kinase type II delta chain -| Gallus gallus (Chicken) Length = 479 Score = 185 bits (469), Expect = 7e-46 Identities = 102/262 (38%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + TG+ A KI++ K L + +++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKITTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 815 YHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL +K++DFGL+ Q E GTP Y++PEV+ Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQ--GEQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP RIT +E + + W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>O14965:STK6_HUMAN Serine/threonine-protein kinase 6 - Homo sapiens (Human)| Length = 403 Score = 184 bits (468), Expect = 9e-46 Identities = 92/263 (34%), Positives = 150/263 (57%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR ++ +A+K+L K ++ K + Q++RE+ +RHPN Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y T++Y+++E G ++ ++ + E Y +L NA+ YCHS+ V Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL + G LK++DFG S + R T CGT +Y+ PE+I + +D Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD- 307 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLWS GV+ + + G PFE + YK+I + +F+ P + + A+ LI ++L N Sbjct: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367 Query: 1175 PNTRITIAEVINNEWFKKGYQPP 1243 P+ R + EV+ + W P Sbjct: 368 PSQRPMLREVLEHPWITANSSKP 390
>P11275:KCC2A_RAT Calcium/calmodulin-dependent protein kinase type II alpha chain -| Rattus norvegicus (Rat) Length = 478 Score = 184 bits (468), Expect = 9e-46 Identities = 104/262 (39%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ V G+ A KI++ K L + +++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 71 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y++ +LVTGGELF+ I +R E DA QQ++ AV +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ + E GTP Y++PEV+ Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKDP 189 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G DLW+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP+ RIT AE + + W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>Q5RCC4:KCC2A_PONPY Calcium/calmodulin-dependent protein kinase type II alpha chain -| Pongo pygmaeus (Orangutan) Length = 478 Score = 184 bits (468), Expect = 9e-46 Identities = 104/262 (39%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ V G+ A KI++ K L + +++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 71 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y++ +LVTGGELF+ I +R E DA QQ++ AV +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ + E GTP Y++PEV+ Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKDP 189 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G DLW+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP+ RIT AE + + W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>P11798:KCC2A_MOUSE Calcium/calmodulin-dependent protein kinase type II alpha chain - Mus| musculus (Mouse) Length = 478 Score = 184 bits (468), Expect = 9e-46 Identities = 104/262 (39%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ V G+ A KI++ K L + +++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 71 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y++ +LVTGGELF+ I +R E DA QQ++ AV +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ + E GTP Y++PEV+ Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKDP 189 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G DLW+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP+ RIT AE + + W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>Q9UQM7:KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II alpha chain -| Homo sapiens (Human) Length = 478 Score = 184 bits (468), Expect = 9e-46 Identities = 104/262 (39%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ V G+ A KI++ K L + +++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 71 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y++ +LVTGGELF+ I +R E DA QQ++ AV +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ + E GTP Y++PEV+ Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKDP 189 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G DLW+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP+ RIT AE + + W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>P21137:KAPC_CAEEL cAMP-dependent protein kinase catalytic subunit - Caenorhabditis| elegans Length = 404 Score = 184 bits (467), Expect = 1e-45 Identities = 103/296 (34%), Positives = 161/296 (54%), Gaps = 14/296 (4%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRM 646 +TLG G+F +V ++ ++G A+KILDK KV+K K + E ++ I P ++ M Sbjct: 85 KTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNM 144 Query: 647 YEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRD 826 + +Y+V+E ++GGE+F + GR E +R Y Q++ A +Y HS + +RD Sbjct: 145 TFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRD 204 Query: 827 LKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKAD 1006 LKPENLL+D+ G LK++DFG + R G T CGTP Y+APE+I +KGY+ A D Sbjct: 205 LKPENLLIDSTGYLKITDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VD 258 Query: 1007 LWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN---- 1174 W+ GV+++ + AGY PF + +Y+KI PS FS K L+K +L + Sbjct: 259 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKR 318 Query: 1175 -PNTRITIAEVINNEWF---------KKGYQPPRFETAEVNLDDINSIFNESGDPA 1312 N + +A++ N++WF +K PP F E N +++ PA Sbjct: 319 YGNLKNGVADIKNHKWFGSTDWIAIYQKKITPPSFSKGESNGRLFEALYPRVDGPA 374
>Q2TA06:STK6_BOVIN Serine/threonine-protein kinase 6 - Bos taurus (Bovine)| Length = 402 Score = 184 bits (466), Expect = 1e-45 Identities = 93/269 (34%), Positives = 151/269 (56%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR ++ +A+K+L K ++ K + Q++RE+ +RHPN Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y T++Y+++E G ++ ++ + E Y +L NA+ YCHS+ V Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL + G LK++DFG S + R T CGT +Y+ PE+I + +D Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD- 307 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLWS GV+ + + G PFE Y++I + +F+ P A+ LI ++L N Sbjct: 308 EKVDLWSLGVLCYEFLVGKPPFEADTYQETYRRISRVEFTFPDCVPEGARDLISRLLKHN 367 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFETAE 1261 P+ R T+ EV+ + W +P + E Sbjct: 368 PSQRPTLKEVLEHPWIIANSKPSSCQKKE 396
>P15791:KCC2D_RAT Calcium/calmodulin-dependent protein kinase type II delta chain -| Rattus norvegicus (Rat) Length = 533 Score = 184 bits (466), Expect = 1e-45 Identities = 101/262 (38%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + TG+ A KI++ K L + +++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 815 YHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL +K++DFGL+ Q + GTP Y++PEV+ Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP RIT +E + + W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>O77708:KCC2D_RABIT Calcium/calmodulin-dependent protein kinase type II delta chain -| Oryctolagus cuniculus (Rabbit) Length = 533 Score = 184 bits (466), Expect = 1e-45 Identities = 101/262 (38%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + TG+ A KI++ K L + +++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 815 YHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL +K++DFGL+ Q + GTP Y++PEV+ Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP RIT +E + + W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q95266:KCC2D_PIG Calcium/calmodulin-dependent protein kinase type II delta chain - Sus| scrofa (Pig) Length = 499 Score = 184 bits (466), Expect = 1e-45 Identities = 101/262 (38%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + TG+ A KI++ K L + +++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 815 YHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL +K++DFGL+ Q + GTP Y++PEV+ Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP RIT +E + + W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q6PHZ2:KCC2D_MOUSE Calcium/calmodulin-dependent protein kinase type II delta chain - Mus| musculus (Mouse) Length = 499 Score = 184 bits (466), Expect = 1e-45 Identities = 101/262 (38%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + TG+ A KI++ K L + +++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 815 YHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL +K++DFGL+ Q + GTP Y++PEV+ Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP RIT +E + + W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q13557:KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II delta chain -| Homo sapiens (Human) Length = 499 Score = 184 bits (466), Expect = 1e-45 Identities = 101/262 (38%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + TG+ A KI++ K L + +++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 815 YHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL +K++DFGL+ Q + GTP Y++PEV+ Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP RIT +E + + W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q2HJF7:KCC2D_BOVIN Calcium/calmodulin-dependent protein kinase type II delta chain - Bos| taurus (Bovine) Length = 488 Score = 184 bits (466), Expect = 1e-45 Identities = 101/262 (38%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + TG+ A KI++ K L + +++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 815 YHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL +K++DFGL+ Q + GTP Y++PEV+ Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP RIT +E + + W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>P11801:KPSH1_HUMAN Serine/threonine-protein kinase H1 - Homo sapiens (Human)| Length = 424 Score = 183 bits (465), Expect = 2e-45 Identities = 99/263 (37%), Positives = 164/263 (62%), Gaps = 8/263 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQI-KREISTMKLIRHP 631 Y++ +G G+F++V + T + AIK+++ K++ ++ + E+ ++ +RH Sbjct: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIET----KYREGREVCESELRVLRRVRHA 153 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 N+I++ EV ++ ++Y+VMEL TGGELFD+I ++G E DA + Q +++ V Y H+ G Sbjct: 154 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 213 Query: 812 VYHRDLKPENLLLDANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 + HRDLKPENLL GT + ++DFGL A +++ +D L+ TTCGTP Y+APEV+ K Sbjct: 214 ITHRDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVRK 272 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSWFSTS--AKKL 1150 Y + D+W+ GVI ++L++G +PFED N LY++I K +S W S S AK Sbjct: 273 PYTNS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDF 331 Query: 1151 IKKILDPNPNTRITIAEVINNEW 1219 I ++L +P R+T + + + W Sbjct: 332 IDRLLTVDPGARMTALQALRHPW 354
>Q0V7M1:KPSH1_BOVIN Serine/threonine-protein kinase H1 - Bos taurus (Bovine)| Length = 424 Score = 183 bits (465), Expect = 2e-45 Identities = 99/263 (37%), Positives = 164/263 (62%), Gaps = 8/263 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQI-KREISTMKLIRHP 631 Y++ +G G+F++V + T + AIK+++ K++ ++ + E+ ++ +RH Sbjct: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIET----KYREGREVCESELRVLRRVRHA 153 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 N+I++ EV ++ ++Y+VMEL TGGELFD+I ++G E DA + Q +++ V Y H+ G Sbjct: 154 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 213 Query: 812 VYHRDLKPENLLLDANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 + HRDLKPENLL GT + ++DFGL A +++ +D L+ TTCGTP Y+APEV+ K Sbjct: 214 ITHRDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVRK 272 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSWFSTS--AKKL 1150 Y + D+W+ GVI ++L++G +PFED N LY++I K +S W S S AK Sbjct: 273 PYTNS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDF 331 Query: 1151 IKKILDPNPNTRITIAEVINNEW 1219 I ++L +P R+T + + + W Sbjct: 332 IDRLLTVDPGARMTALQALRHPW 354
>P22517:KCC2_YEAST Calcium/calmodulin-dependent protein kinase II - Saccharomyces| cerevisiae (Baker's yeast) Length = 447 Score = 183 bits (465), Expect = 2e-45 Identities = 111/290 (38%), Positives = 162/290 (55%), Gaps = 10/290 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQ-IKREISTMKLIRHP 631 Y GRTLG G+F V+ AR + T E+VAIKIL K + + + Q + E+S ++ + HP Sbjct: 47 YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHP 106 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 N++ + S+ K YIV +L TGGELFD+I SRG+ E DA + Q++ AV+Y HS+ Sbjct: 107 NIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKN 166 Query: 812 VYHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 V HRDLKPEN+L N L ++DFG++ Q E+ L++ G+ YVAPEV+ Sbjct: 167 VVHRDLKPENVLYVDKSENSPLVIADFGIA--KQLKGEEDLIYKAAGSLGYVAPEVLTQD 224 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKI----YKADFSCPSW--FSTSAK 1144 G+ G D+WS GVI + L+ GY PF ++ ++ Y F P W S K Sbjct: 225 GH-GKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVK 283 Query: 1145 KLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFN 1294 + I K L NP R T E++++ W R ET+ + L D+ F+ Sbjct: 284 RFILKALRLNPADRPTATELLDDPWITS----KRVETSNI-LPDVKKGFS 328
>P06244:KAPA_YEAST cAMP-dependent protein kinase type 1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 397 Score = 183 bits (465), Expect = 2e-45 Identities = 91/263 (34%), Positives = 154/263 (58%), Gaps = 5/263 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +++ RTLG G+F +V R+ G A+K+L K+ V++ K + E + ++ HP Sbjct: 87 FQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPF 146 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IRM+ +I+++M+ + GGELF + R A+ Y ++ A++Y HS+ + Sbjct: 147 IIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDI 206 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPEN+LLD NG +K++DFG + V +T CGTP+Y+APEV++ K Y+ Sbjct: 207 IYRDLKPENILLDKNGHIKITDFGFAKYVPDV-----TYTLCGTPDYIAPEVVSTKPYN- 260 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 D WS G++++ ++AGY PF DSN M Y+KI A+ P +F+ K L+ +++ + Sbjct: 261 KSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRD 320 Query: 1175 PNTRI-----TIAEVINNEWFKK 1228 + R+ +V N+ WFK+ Sbjct: 321 LSQRLGNLQNGTEDVKNHPWFKE 343
>Q91YA2:KPSH1_MOUSE Serine/threonine-protein kinase H1 - Mus musculus (Mouse)| Length = 424 Score = 183 bits (464), Expect = 3e-45 Identities = 98/263 (37%), Positives = 164/263 (62%), Gaps = 8/263 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQI-KREISTMKLIRHP 631 Y++ +G G+F++V + T + AIK+++ K++ ++ + E+ ++ +RH Sbjct: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIET----KYREGREVCESELRVLRRVRHA 153 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 N+I++ EV ++ ++Y+VMEL TGGELFD+I ++G E DA + Q +++ V Y H+ G Sbjct: 154 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 213 Query: 812 VYHRDLKPENLLLDANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 + HRDLKPENLL GT + ++DFGL A +++ +D L+ TTCGTP Y+APEV+ K Sbjct: 214 ITHRDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVRK 272 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSC--PSWFSTS--AKKL 1150 Y + D+W+ GVI ++L++G +PFED N LY++I + +S W S S AK Sbjct: 273 PYTNS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDF 331 Query: 1151 IKKILDPNPNTRITIAEVINNEW 1219 I ++L +P R+T + + + W Sbjct: 332 IDRLLTVDPGARMTALQALRHPW 354
>Q9UQB9:AURKC_HUMAN Serine/threonine-protein kinase 13 - Homo sapiens (Human)| Length = 309 Score = 183 bits (464), Expect = 3e-45 Identities = 91/255 (35%), Positives = 147/255 (57%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR E+ VA+K+L K ++ K + Q++REI ++HPN Sbjct: 43 FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPN 102 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y ++Y+++E GEL+ ++ +L E ++L +A+ YCH + V Sbjct: 103 ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKV 162 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL G +K++DFG S + +R T CGT +Y+ PE+I + YD Sbjct: 163 IHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRR----KTMCGTLDYLPPEMIEGRTYD- 217 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLW GV+ + L+ GY PFE ++ Y++I K D P A+ LI ++L Sbjct: 218 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 277 Query: 1175 PNTRITIAEVINNEW 1219 P R+ +A+++ + W Sbjct: 278 PLERLPLAQILKHPW 292
>Q6DGS3:KCC2D_DANRE Calcium/calmodulin-dependent protein kinase type II delta chain -| Danio rerio (Zebrafish) (Brachydanio rerio) Length = 493 Score = 181 bits (460), Expect = 7e-45 Identities = 101/262 (38%), Positives = 154/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + +G+ A KI++ K L + +++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKISSGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 71 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V +CH G+ Sbjct: 72 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHVNGI 131 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ Sbjct: 132 VHRDLKPENLLLASKMKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKDP 189 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 190 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP+ RIT AE + W Sbjct: 249 NKMLTINPSKRITAAEAPKHPW 270
>Q00168:KCC2A_DROME Calcium/calmodulin-dependent protein kinase type II alpha chain -| Drosophila melanogaster (Fruit fly) Length = 530 Score = 181 bits (460), Expect = 7e-45 Identities = 101/262 (38%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ LG+G F+ VK TG A KI++ K L + +++RE + + HPN Sbjct: 14 YDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKK-LTARDFQKLEREARICRKLHHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ + Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH GV Sbjct: 73 IVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGV 132 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ + Sbjct: 133 VHRDLKPENLLLASKAKGAAVKLADFGLAIEVQ--GDHQAWFGFAGTPGYLSPEVLKKEP 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY +I D+ P W + AK LI Sbjct: 191 Y-GKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 ++L NPN RIT AE + + W Sbjct: 250 NQMLTVNPNKRITAAEALKHPW 271
>Q96GD4:AURKB_HUMAN Serine/threonine-protein kinase 12 - Homo sapiens (Human)| Length = 344 Score = 181 bits (460), Expect = 7e-45 Identities = 93/257 (36%), Positives = 148/257 (57%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR ++ VA+K+L K ++ K + Q++REI + HPN Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPN 136 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y R +IY+++E GEL+ ++ E ++L +A+ YCH + V Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKV 196 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL G LK++DFG S + +R T CGT +Y+ PE+I + ++ Sbjct: 197 IHRDIKPENLLLGLKGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRMHN- 251 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLW GV+ + L+ G PFE ++ Y++I K D P+ T A+ LI K+L N Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 311 Query: 1175 PNTRITIAEVINNEWFK 1225 P+ R+ +A+V + W + Sbjct: 312 PSERLPLAQVSAHPWVR 328
>Q4KTY1:KPSH1_PINFU Serine/threonine-protein kinase H1 homolog - Pinctada fucata (Pearl| oyster) Length = 415 Score = 181 bits (459), Expect = 1e-44 Identities = 97/262 (37%), Positives = 158/262 (60%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++ +G G F+KV + T + AIK++D+ ++ K + + E++ ++ ++H Sbjct: 80 YDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDR---VQGKEV--FESEVAVLRRVKHSY 134 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++ EV ++ K+Y+VMEL TGGELFD+I ++G E DA + +++ V Y H G+ Sbjct: 135 IIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNMVLDGVKYLHGLGI 194 Query: 815 YHRDLKPENLLLDANG---TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLL G + ++DFGLS S + + + TTCGTP Y+APE+I K Sbjct: 195 THRDLKPENLLYYHPGHDSKIMITDFGLS--STRKGPENFMRTTCGTPEYIAPEIIARKP 252 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPS--W--FSTSAKKLI 1153 Y + D+W+ GVI ++L++G +PF+D N LY+ I KA +S W S AK I Sbjct: 253 Y-MCQVDMWAVGVITYILLSGTMPFDDENKTRLYRLILKAKYSYAGEHWKDVSAQAKDFI 311 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L +P R++ A+ + ++W Sbjct: 312 DKLLVVSPGDRLSAADALKHQW 333
>Q9P7I2:KCC1_SCHPO Calcium/calmodulin-dependent protein kinase type I -| Schizosaccharomyces pombe (Fission yeast) Length = 335 Score = 181 bits (459), Expect = 1e-44 Identities = 100/267 (37%), Positives = 156/267 (58%), Gaps = 9/267 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLI--RH 628 Y +GR LG GT+A V+ A ++ET + A KI++K + K + +K EI+ +K + H Sbjct: 31 YRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDF--VKNEIAILKRVSYEH 88 Query: 629 PNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSR 808 PN++ + + + +Y++ EL TGGELFD+I ++G E DA + +AV Y H Sbjct: 89 PNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDN 148 Query: 809 GVYHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINN 979 G+ HRDLKPENLL D N L ++DFGLS + + +L T CGTP Y+APEV Sbjct: 149 GIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYED-SQYYMLMTACGTPEYMAPEVFRR 207 Query: 980 KGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFS----CPSWFSTSAKK 1147 GY G D+W+ GVI + L++GY PF + + + + I +++ C S S +AK Sbjct: 208 TGY-GKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAKD 266 Query: 1148 LIKKILDPNPNTRITIAEVINNEWFKK 1228 IKK L+ +P+ R+T A+ + + + + Sbjct: 267 FIKKCLENDPSKRLTAADALKHPFLSE 293
>P06245:KAPB_YEAST cAMP-dependent protein kinase type 2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 380 Score = 181 bits (459), Expect = 1e-44 Identities = 93/245 (37%), Positives = 141/245 (57%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +++ RTLG G+F +V R+V G AIK+L K +V+K K + E +KL+ HP Sbjct: 70 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPF 129 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IRM+ I++VM+ + GGELF + R A+ Y ++I A++Y H+ + Sbjct: 130 LIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNI 189 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPEN+LLD NG +K++DFG + Q V T CGTP+Y+APEVI K Y+ Sbjct: 190 IYRDLKPENILLDRNGHIKITDFGFAKEVQTV-----TWTLCGTPDYIAPEVITTKPYN- 243 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 D WS GV+++ ++AGY PF D+ M Y+KI + P +F L+ K++ + Sbjct: 244 KSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITAD 303 Query: 1175 PNTRI 1189 RI Sbjct: 304 LTRRI 308
>P28583:CDPK_SOYBN Calcium-dependent protein kinase SK5 - Glycine max (Soybean)| Length = 508 Score = 181 bits (459), Expect = 1e-44 Identities = 130/361 (36%), Positives = 188/361 (52%), Gaps = 14/361 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMK-LIRHP 631 YE+GR LG+G F +G A K + K K+L + + REI M L H Sbjct: 34 YEVGRKLGQGQFGTTFECTRRASGGKFACKSIPKRKLLCKEDYEDVWREIQIMHHLSEHA 93 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 NV+R+ T +++VMEL GGELFD+I +G E A + + ++ V+ CHS G Sbjct: 94 NVVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKTIVEVVEACHSLG 153 Query: 812 VYHRDLKPENLL---LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 V HRDLKPEN L +D + LK +DFGLS + G+P YVAPEV+ K Sbjct: 154 VMHRDLKPENFLFDTIDEDAKLKATDFGLSVF---YKPGESFCDVVGSPYYVAPEVL-RK 209 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKL 1150 Y G ++D+WS GVIL++L++G PF + ++++I K DF W S SAK L Sbjct: 210 LY-GPESDVWSAGVILYILLSGVPPFWAESEPGIFRQILLGKLDFHSEPWPSISDSAKDL 268 Query: 1151 IKKILDPNPNTRITIAEVINNEWFKKGYQPP--RFETAEVNLDDINSIFNESGDPAQLVV 1324 I+K+LD NP TR+T EV+ + W P ++A ++ S N+ A V+ Sbjct: 269 IRKMLDQNPKTRLTAHEVLRHPWIVDDNIAPDKPLDSAVLSRLKQFSAMNKLKKMALRVI 328 Query: 1325 ERR---EERPAVMNAFELISTSQGLNLGTL-FEKQTDSVKRETRFASRLPANEILSKIEA 1492 R EE + F++I T N GT+ F++ D +K R S L +EI ++A Sbjct: 329 AERLSEEEIGGLKELFKMIDTD---NSGTITFDELKDGLK---RVGSELMESEIKDLMDA 382 Query: 1493 A 1495 A Sbjct: 383 A 383
>Q9D2E1:TSSK3_MOUSE Testis-specific serine/threonine-protein kinase 3 - Mus musculus| (Mouse) Length = 268 Score = 181 bits (458), Expect = 1e-44 Identities = 100/257 (38%), Positives = 159/257 (61%), Gaps = 2/257 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+LG+T+GEGT++KVK A + + VAIKI+DK + + + RE+ ++ + H N Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 635 VIRMYEVMASRT-KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 +I++YE++ S KIY+VMEL GG++FD + + G L E A+ F+Q++ A+ YCH G Sbjct: 70 IIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 991 V HRDLK EN LL LK++DFG + + + R + L T CG+ Y APEV+ +D Sbjct: 130 VAHRDLKCENALLQ-GFNLKLTDFGFAKVLPKSRRE-LSQTFCGSTAYAAPEVLQGIPHD 187 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNL-MALYKKIYKADFSCPSWFSTSAKKLIKKILD 1168 K D+WS GV+L+V++ LPF+D+++ L+++ F ST + L+K++L+ Sbjct: 188 SKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLGISTECQDLLKRLLE 247 Query: 1169 PNPNTRITIAEVINNEW 1219 P+ R +I EV + W Sbjct: 248 PDMILRPSIEEVSWHPW 264
>Q61XD3:AIR2_CAEBR Aurora/Ipl1-related protein kinase 2 - Caenorhabditis briggsae| Length = 302 Score = 181 bits (458), Expect = 1e-44 Identities = 92/255 (36%), Positives = 144/255 (56%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR + AIK+L K +++ + Q++REI ++HPN Sbjct: 27 FEIGRPLGKGKFGSVYLARTKTGHFHCAIKVLFKSQLISGGVEHQLEREIEIQSHLQHPN 86 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IR+Y KIY+++E GGE++ ++ ++ R E A KY ++ +A+ YCH + V Sbjct: 87 IIRLYNYFWDAKKIYLILEYAPGGEMYKQLTTQKRFTEAMAGKYMYEIADALSYCHRKNV 146 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLL+ A G LK+ DFG S + + T CGT +Y+ PE++N + Sbjct: 147 IHRDIKPENLLIGAQGELKIGDFGWSVHAPSNKR----QTMCGTMDYLPPEMVNGNSHSD 202 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A DLW+ GV+ + + G PFE N Y I F+ P + A+ LI K+L + Sbjct: 203 A-VDLWAIGVLCYEFLVGKPPFEHENQADTYSAIKAGRFTYPDFVKKGARDLIGKLLVVD 261 Query: 1175 PNTRITIAEVINNEW 1219 P R ++ EV ++ W Sbjct: 262 PRRRCSLQEVKDHYW 276
>Q96PF2:TSSK2_HUMAN Testis-specific serine/threonine-protein kinase 2 - Homo sapiens| (Human) Length = 358 Score = 180 bits (457), Expect = 2e-44 Identities = 103/269 (38%), Positives = 158/269 (58%), Gaps = 5/269 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y +G LG+G++AKVK A + NVA+KI+D+ K + + RE+ + + H + Sbjct: 12 YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGS 71 Query: 635 VIRMYEVM-ASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 +I+ YE+ S +IYI+MEL G+L + I +G L ED ARK F+QL +AV YCH Sbjct: 72 IIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLD 131 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLS--ALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 + HRDLK ENLLLD + +K+SDFG S L L T CG+ Y APEV+ + Sbjct: 132 IVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIP 191 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNL--MALYKKIYKADFSCPSWFSTSAKKLIKK 1159 Y D+WS GVIL++++ G +P++DS++ M +K ++ DF + K LI + Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYR 251 Query: 1160 ILDPNPNTRITIAEVINNEWFKKGYQPPR 1246 +L P+ + R+ I E++++ W QPP+ Sbjct: 252 MLQPDVSQRLHIDEILSHSWL----QPPK 276
>P00517:KAPCA_BOVIN cAMP-dependent protein kinase, alpha-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 180 bits (457), Expect = 2e-44 Identities = 96/261 (36%), Positives = 151/261 (57%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V +++ETG + A+KILDK KV+K K I E ++ + P Sbjct: 44 FERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + + ++ N++WF Sbjct: 278 LTKRFGNLKNGVNDIKNHKWF 298
>O61661:CHK1_DROME Serine/threonine-protein kinase grp - Drosophila melanogaster (Fruit| fly) Length = 512 Score = 180 bits (457), Expect = 2e-44 Identities = 97/261 (37%), Positives = 160/261 (61%), Gaps = 6/261 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQ-IKREISTMKLIRHP 631 + L +TLGEG + +VK N +TGE VA+K++D + KH A +++E+ K+++ Sbjct: 22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVD---LKKHPDAANSVRKEVCIQKMLQDK 78 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 +++R + + + YI +E GGELFD+I + + +A++YF QL++ ++Y H RG Sbjct: 79 HILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRG 138 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 991 + HRDLKPENLLLD + +K+SDFG++ + + ++ LL CGT YVAPEV+ K Y Sbjct: 139 IAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYH 197 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKAD----FSCP-SWFSTSAKKLIK 1156 ADLWSCGVIL ++AG LP++ + ++ + P S T A L++ Sbjct: 198 AQPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLR 257 Query: 1157 KILDPNPNTRITIAEVINNEW 1219 K+L +P TR+T+ + ++++W Sbjct: 258 KLLATSPGTRLTLEKTLDHKW 278
>O55099:AURKB_RAT Serine/threonine-protein kinase 12 - Rattus norvegicus (Rat)| Length = 343 Score = 180 bits (457), Expect = 2e-44 Identities = 93/257 (36%), Positives = 146/257 (56%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR ++ VA+KIL K ++ K + Q++REI ++HPN Sbjct: 80 FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPN 139 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++Y + +IY+++E GEL+ ++ G E ++L +A+ YCH + V Sbjct: 140 ILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELSDALMYCHKKKV 199 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL G LK++DFG S + +R T CGT +Y+ PE+I + ++ Sbjct: 200 IHRDIKPENLLLGLQGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRMHN- 254 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 DLW GV+ + LM G PFE + Y++I K D PS AK LI K+L N Sbjct: 255 EMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMPLGAKDLISKLLKHN 314 Query: 1175 PNTRITIAEVINNEWFK 1225 P+ R+ + +V + W + Sbjct: 315 PSQRLPLEQVSAHPWVR 331
>P05986:KAPC_YEAST cAMP-dependent protein kinase type 3 - Saccharomyces cerevisiae| (Baker's yeast) Length = 398 Score = 180 bits (456), Expect = 2e-44 Identities = 91/263 (34%), Positives = 151/263 (57%), Gaps = 5/263 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +++ RTLG G+F +V R+ G A+K L K ++K K + E + ++ HP Sbjct: 88 FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPF 147 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +IRM+ ++++VM+ + GGELF + R A+ Y ++ A++Y HS+ + Sbjct: 148 IIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDI 207 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPEN+LLD NG +K++DFG + V +T CGTP+Y+APEV++ K Y+ Sbjct: 208 IYRDLKPENILLDKNGHIKITDFGFAKYVPDV-----TYTLCGTPDYIAPEVVSTKPYN- 261 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 D WS GV+++ ++AGY PF +SN M Y+ I A+ P +F A+ L+KK++ + Sbjct: 262 KSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRD 321 Query: 1175 PNTRI-----TIAEVINNEWFKK 1228 + R+ +V N+ WF + Sbjct: 322 LSERLGNLQNGSEDVKNHPWFNE 344
>Q9MZD9:KAPCA_SHEEP cAMP-dependent protein kinase, alpha-catalytic subunit - Ovis aries| (Sheep) Length = 351 Score = 180 bits (456), Expect = 2e-44 Identities = 96/261 (36%), Positives = 150/261 (57%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ ETG + A+KILDK KV+K K I E ++ + P Sbjct: 44 FERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + + ++ N++WF Sbjct: 278 LTKRFGNLKNGVNDIKNHKWF 298
>P22612:KAPCG_HUMAN cAMP-dependent protein kinase, gamma-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 179 bits (455), Expect = 3e-44 Identities = 99/261 (37%), Positives = 150/261 (57%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E RTLG G+F +V R+ ETG + A+KIL+K KV+K K + I E ++ I P Sbjct: 44 FERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++ + +Y+VME V GGE+F ++ GR E A Y Q++ AV Y HS + Sbjct: 104 LVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPENLL+D G L+V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IHRDLKPENLLIDQQGYLQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + G+ PF + +Y+KI PS S+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N R + ++ N++WF Sbjct: 278 LTKRFGNLRNGVGDIKNHKWF 298
>P36887:KAPCA_PIG cAMP-dependent protein kinase, alpha-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 179 bits (455), Expect = 3e-44 Identities = 96/261 (36%), Positives = 150/261 (57%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ ETG + A+KILDK KV+K K I E ++ + P Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 104 LVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + + ++ N++WF Sbjct: 278 LTKRFGNLKNGVNDIKNHKWF 298
>Q9DG02:KCC2D_XENLA Calcium/calmodulin-dependent protein kinase type II delta chain -| Xenopus laevis (African clawed frog) Length = 475 Score = 179 bits (454), Expect = 4e-44 Identities = 99/262 (37%), Positives = 152/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + G+ A KI++ K L + +++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCIKINIGQEYAAKIINTKK-LSARDHQKLEREAKICRLLKHPN 71 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH G+ Sbjct: 72 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 131 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKDP 189 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 190 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NP RI E + + W Sbjct: 249 NKMLTINPAKRINATEALRHPW 270
>P17612:KAPCA_HUMAN cAMP-dependent protein kinase, alpha-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 179 bits (454), Expect = 4e-44 Identities = 96/261 (36%), Positives = 150/261 (57%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ ETG + A+KILDK KV+K K I E ++ + P Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + + ++ N++WF Sbjct: 278 LTKRFGNLKNGVNDIKNHKWF 298
>Q8MJ44:KAPCA_CANFA cAMP-dependent protein kinase, alpha-catalytic subunit - Canis| familiaris (Dog) Length = 350 Score = 179 bits (454), Expect = 4e-44 Identities = 96/261 (36%), Positives = 150/261 (57%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ ETG + A+KILDK KV+K K I E ++ + P Sbjct: 43 FERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 102 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 103 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 162 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 163 IYRDLKPENLLIDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 217 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 218 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 276 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + + ++ N++WF Sbjct: 277 LTKRFGNLKNGVNDIKNHKWF 297
>Q6CWQ4:IPL1_KLULA Spindle assembly checkpoint kinase - Kluyveromyces lactis (Yeast)| (Candida sphaerica) Length = 361 Score = 179 bits (453), Expect = 5e-44 Identities = 90/256 (35%), Positives = 154/256 (60%), Gaps = 1/256 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+G+ LG+G F KV ++ ETG A+K ++K +++++ + Q +RE+ +H N Sbjct: 100 FEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFKHKN 159 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 + ++Y ++Y++ME V GEL+ + + G L E A + Q+ NA+DY HS+ + Sbjct: 160 LTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKNI 219 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLH-TTCGTPNYVAPEVINNKGYD 991 HRD+KPEN+L+ N T+K++DFG S + EDG T CGT +Y++PE+I ++ Y+ Sbjct: 220 LHRDIKPENILIGFNNTIKLTDFGWSVYN----EDGQKRKTLCGTIDYLSPELIKSREYN 275 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 K D+W+ GV+ + L+ G PFE+ Y++I + D P S A+ LI ++L Sbjct: 276 N-KVDVWALGVLTYELLVGSPPFEEDTKEMTYRRILRCDLKFPLNVSPQARDLIVRLLQF 334 Query: 1172 NPNTRITIAEVINNEW 1219 P+ RI ++EV ++ W Sbjct: 335 EPSKRIPLSEVKSHAW 350
>Q8BWQ5:DCLK3_MOUSE Serine/threonine-protein kinase DCLK3 - Mus musculus (Mouse)| Length = 619 Score = 179 bits (453), Expect = 5e-44 Identities = 96/267 (35%), Positives = 160/267 (59%), Gaps = 10/267 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y++G +G+G FA VK R+ ET + A+K++DK ++ + I + EI ++ + HPN Sbjct: 343 YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDKSQLKGKEDI--VDSEILIIQSLSHPN 400 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV + +IY++ME V GG+LFD I + E +A L A+ + H + + Sbjct: 401 IVKLHEVYETEAEIYLIMEYVQGGDLFDAIVENVKFPEPEAAVMITDLCKALVHMHDKNI 460 Query: 815 YHRDLKPENLLLDANG----TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 HRD+KPENLL+ N TLK++DFGL+ VR + T CGTP YVAPE+++ K Sbjct: 461 VHRDVKPENLLVQRNEDKSITLKLADFGLA--KYVVRP---IFTVCGTPTYVAPEILSEK 515 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSW--FSTSAK 1144 GY G + D+W+ GVIL++L+ G+ PF D + + ++ + +F P W S +AK Sbjct: 516 GY-GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAK 574 Query: 1145 KLIKKILDPNPNTRITIAEVINNEWFK 1225 L++ +L+ +P R T +V+ + W + Sbjct: 575 DLVRNLLEVDPKKRYTAEQVLQHPWIE 601
>Q9C098:DCLK3_HUMAN Serine/threonine-protein kinase DCLK3 - Homo sapiens (Human)| Length = 648 Score = 179 bits (453), Expect = 5e-44 Identities = 102/267 (38%), Positives = 159/267 (59%), Gaps = 10/267 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE GR +G+G FA VK R+ ET + A+KI+DK + LK K + EI ++ + HPN Sbjct: 356 YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSR-LKGKE-DMVDSEILIIQSLSHPN 413 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +++++EV + +IY+++E V GG+LFD I + E DA L A+ + H + + Sbjct: 414 IVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSI 473 Query: 815 YHRDLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 HRDLKPENLL+ D + TLK++DFGL+ VR + T CGTP YVAPE+++ K Sbjct: 474 VHRDLKPENLLVQRNEDKSTTLKLADFGLA--KHVVRP---IFTVCGTPTYVAPEILSEK 528 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSW--FSTSAK 1144 GY G + D+W+ GVIL++L+ G+ PF D + + ++ +F P W S +AK Sbjct: 529 GY-GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAK 587 Query: 1145 KLIKKILDPNPNTRITIAEVINNEWFK 1225 L+ ++L +P R T +V+ + W + Sbjct: 588 DLVSRLLVVDPKKRYTAHQVLQHPWIE 614
>Q9N0X0:AURKB_PIG Serine/threonine-protein kinase 12 - Sus scrofa (Pig)| Length = 344 Score = 179 bits (453), Expect = 5e-44 Identities = 92/257 (35%), Positives = 147/257 (57%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR ++ VA+K+L K ++ K + Q++REI ++HPN Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLQHPN 136 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y R +IY+++E GEL+ ++ E ++L +A+ YCH + V Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKCRTFDEQRTATIMEELADALIYCHGKKV 196 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL G LK++DFG S + +R T CGT +Y+ PE+I + ++ Sbjct: 197 IHRDIKPENLLLGLQGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRTHN- 251 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLW GV+ + L+ G PFE ++ Y++I K D P A+ LI K+L N Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIGKVDLKFPPSVPAGAQDLISKLLKHN 311 Query: 1175 PNTRITIAEVINNEWFK 1225 P+ R+ +A+V + W + Sbjct: 312 PSDRLPLAQVSAHPWVR 328
>Q7YRC6:AURKB_BOVIN Serine/threonine-protein kinase 12 - Bos taurus (Bovine)| Length = 344 Score = 179 bits (453), Expect = 5e-44 Identities = 91/257 (35%), Positives = 147/257 (57%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR ++ VA+K+L K ++ K + Q++REI ++HPN Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLQHPN 136 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+Y R +IY+++E GEL+ ++ E ++L +A+ YCH++ V Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELADALTYCHAKKV 196 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL G LK++DFG S + +R T CGT +Y+ PE+I + ++ Sbjct: 197 IHRDIKPENLLLGLRGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRTHN- 251 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 K DLW GV+ + L+ G PFE ++ Y++I K D P A+ I K+L N Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPPSVPLGAQDFIYKLLKHN 311 Query: 1175 PNTRITIAEVINNEWFK 1225 P+ R+ +A+V + W + Sbjct: 312 PSERLPLAQVSAHPWVR 328
>O61267:LOK_DROME Ovarian-specific serine/threonine-protein kinase Lok - Drosophila| melanogaster (Fruit fly) Length = 476 Score = 178 bits (452), Expect = 6e-44 Identities = 103/272 (37%), Positives = 157/272 (57%), Gaps = 15/272 (5%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIA------QIKREISTMK 616 Y + R LG G + V+ + T + A+KI+ K+ + + ++ E MK Sbjct: 174 YYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMK 233 Query: 617 LIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDY 796 + HP V+RM++++ +Y+V+E + GG+L ++I S L ED ++ YF Q+ +AV Y Sbjct: 234 NLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKY 293 Query: 797 CHSRGVYHRDLKPENLLLDANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPE 967 H RG+ HRDLKP+N+LL+ N LKVSDFGLS V++D ++ T CGTP YVAPE Sbjct: 294 LHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKF---VQKDSVMRTLCGTPLYVAPE 350 Query: 968 VINNKGYDG--AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSC--PSWFST 1135 V+ G + K D+WS GV+LF ++G LPF D ++I K F+ PSW S Sbjct: 351 VLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSV 410 Query: 1136 S--AKKLIKKILDPNPNTRITIAEVINNEWFK 1225 S AK LI ++L +P R +I +V+ + W + Sbjct: 411 SQRAKLLINQMLIVDPERRPSIDDVLQSSWLR 442
>P34099:KAPC_DICDI cAMP-dependent protein kinase catalytic subunit - Dictyostelium| discoideum (Slime mold) Length = 648 Score = 178 bits (452), Expect = 6e-44 Identities = 90/257 (35%), Positives = 144/257 (56%), Gaps = 5/257 (1%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRM 646 R LG GTF KV +N + G A+K L+K V++ K + + E S + I HP ++ + Sbjct: 340 RVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVNL 399 Query: 647 YEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRD 826 Y+ K+Y++ E V GGE+F + + A+ Y +++ A+++ H + + +RD Sbjct: 400 YQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQNIVYRD 459 Query: 827 LKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKAD 1006 LKPENLL+D G +K++DFG + R + T CGTP Y+APE+I +KG+ G D Sbjct: 460 LKPENLLIDNQGHIKITDFGFAK-----RVEDRTFTLCGTPEYLAPEIIQSKGH-GKAVD 513 Query: 1007 LWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTR 1186 W+ G+++F ++AGY PF D + A+Y KI + P F AK LIK++L + R Sbjct: 514 WWALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRLLTADRTRR 573 Query: 1187 I-----TIAEVINNEWF 1222 + +V N+ WF Sbjct: 574 LGALKDGALDVKNHRWF 590
>P25321:KAPCA_CRIGR cAMP-dependent protein kinase, alpha-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 178 bits (452), Expect = 6e-44 Identities = 95/257 (36%), Positives = 148/257 (57%), Gaps = 5/257 (1%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRM 646 +TLG G+F +V ++ ETG + A+KILDK KV+K K I E ++ + P ++++ Sbjct: 48 KTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107 Query: 647 YEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRD 826 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RD Sbjct: 108 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167 Query: 827 LKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKAD 1006 LKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D Sbjct: 168 LKPENLLIDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VD 221 Query: 1007 LWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN---- 1174 W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281 Query: 1175 -PNTRITIAEVINNEWF 1222 N + + ++ N++WF Sbjct: 282 FGNLKNGVNDIKNHKWF 298
>P38991:IPL1_YEAST Spindle assembly checkpoint kinase - Saccharomyces cerevisiae| (Baker's yeast) Length = 367 Score = 178 bits (452), Expect = 6e-44 Identities = 86/255 (33%), Positives = 146/255 (57%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +ELG+ LG+G F KV R+ TG A+K+++K++++K+ + Q +RE+ + HPN Sbjct: 104 FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPN 163 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 + + Y ++Y++ME + GE++ + G + A Y Q+ NA+DY H + + Sbjct: 164 LTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNI 223 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPEN+L+ N +K++DFG S ++ + T CGT +Y++PE++ ++ YD Sbjct: 224 IHRDIKPENILIGFNNVIKLTDFGWSIINP---PENRRKTVCGTIDYLSPEMVESREYDH 280 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 D W+ GV+ F L+ G PFE+ YK+I D PS S A+ LI K+L + Sbjct: 281 T-IDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYD 339 Query: 1175 PNTRITIAEVINNEW 1219 P R+ + +V + W Sbjct: 340 PKDRMRLGDVKMHPW 354
>O70126:AURKB_MOUSE Serine/threonine-protein kinase 12 - Mus musculus (Mouse)| Length = 345 Score = 178 bits (452), Expect = 6e-44 Identities = 93/257 (36%), Positives = 146/257 (56%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR ++ VA+KIL K ++ K + Q++REI ++HPN Sbjct: 82 FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPN 141 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++Y + +IY+++E GEL+ ++ E ++L +A+ YCH + V Sbjct: 142 ILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDALTYCHKKKV 201 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLLL G LK++DFG S + +R T CGT +Y+ PE+I + ++ Sbjct: 202 IHRDIKPENLLLGLQGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRMHN- 256 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 DLW GV+ + LM G PFE + Y++I K D PS + A+ LI K+L N Sbjct: 257 EMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDLISKLLKHN 316 Query: 1175 PNTRITIAEVINNEWFK 1225 P R+ +AEV + W + Sbjct: 317 PWQRLPLAEVAAHPWVR 333
>Q2TA25:PLK1_BOVIN Serine/threonine-protein kinase PLK1 - Bos taurus (Bovine)| Length = 602 Score = 177 bits (450), Expect = 1e-43 Identities = 113/320 (35%), Positives = 165/320 (51%), Gaps = 16/320 (5%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G FAK + +T E A KI+ K +LK ++ EIS + + H + Sbjct: 51 YLRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQH 110 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+ + +++V+EL L + R L E +AR Y +Q++ Y H V Sbjct: 111 VVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHGNRV 170 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDG-LLHTTCGTPNYVAPEVINNKGYD 991 HRDLK NL L+ + +K+ DFGL+ +V DG T CGTPNY+APEV++ KG+ Sbjct: 171 IHRDLKLGNLFLNEDLEVKIGDFGLAT---KVEYDGERKKTLCGTPNYIAPEVLSKKGH- 226 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 + D+WS G I++ L+ G PFE S L Y +I ++S P + A LIKK+L P Sbjct: 227 SFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKNNEYSIPKHINPVASSLIKKMLQP 286 Query: 1172 NPNTRITIAEVINNEWFKKGY-----------QPPRFETAEVNLDDIN----SIFNESGD 1306 +P R TI E++N+E+F GY PPRF A +LD N ++ N+ + Sbjct: 287 DPTARPTIHELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGME 346 Query: 1307 PAQLVVERREERPAVMNAFE 1366 R +E P V A E Sbjct: 347 NPMPERPREKEEPVVREASE 366
>P27466:KCC1_YEAST Calcium/calmodulin-dependent protein kinase I - Saccharomyces| cerevisiae (Baker's yeast) Length = 446 Score = 177 bits (450), Expect = 1e-43 Identities = 100/265 (37%), Positives = 153/265 (57%), Gaps = 10/265 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKM-IAQIKREISTMKLIRHP 631 Y G+TLG GTF V+ A+N ETGE+VA+KIL K + +K+ + + E+ ++ + HP Sbjct: 37 YVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHP 96 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 N++ + S+ K YI+ +L GGELFD+I +G+ E+DA + ++++AV Y HS+ Sbjct: 97 NIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQN 156 Query: 812 VYHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 + HRDLKPENLL L V+DFG++ + ++ LL+ G+ YVAPEV+ Sbjct: 157 IVHRDLKPENLLYIDKSDESPLVVADFGIA--KRLKSDEELLYKPAGSLGYVAPEVLTQD 214 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKI----YKADFSCPSWFSTS--AK 1144 G+ G D+WS GVI + L+ GY F + + Y F P W S S AK Sbjct: 215 GH-GKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAK 273 Query: 1145 KLIKKILDPNPNTRITIAEVINNEW 1219 + I K L+ +P+ R T AE++ + W Sbjct: 274 QFILKALNLDPSKRPTAAELLEDPW 298
>P05132:KAPCA_MOUSE cAMP-dependent protein kinase, alpha-catalytic subunit - Mus musculus| (Mouse) Length = 351 Score = 177 bits (449), Expect = 1e-43 Identities = 94/257 (36%), Positives = 148/257 (57%), Gaps = 5/257 (1%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRM 646 +TLG G+F +V ++ E+G + A+KILDK KV+K K I E ++ + P ++++ Sbjct: 48 KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107 Query: 647 YEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRD 826 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RD Sbjct: 108 EFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167 Query: 827 LKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKAD 1006 LKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D Sbjct: 168 LKPENLLIDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VD 221 Query: 1007 LWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN---- 1174 W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281 Query: 1175 -PNTRITIAEVINNEWF 1222 N + + ++ N++WF Sbjct: 282 FGNLKNGVNDIKNHKWF 298
>P53681:CRK_DAUCA CDPK-related protein kinase - Daucus carota (Carrot)| Length = 602 Score = 177 bits (449), Expect = 1e-43 Identities = 101/269 (37%), Positives = 157/269 (58%), Gaps = 12/269 (4%) Frame = +2 Query: 455 YELGRTLGEGTFA---KVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMK-LI 622 +E+G +G G F + KF + G++VA+K++ K K+ I ++RE+ ++ L Sbjct: 148 FEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIEDVRREVKILRALT 207 Query: 623 RHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRG-RLKEDDARKYFQQLINAVDYC 799 H N+++ Y+ T +Y+VMEL GGEL D+I SRG + EDDA+ Q++N V +C Sbjct: 208 GHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVAFC 267 Query: 800 HSRGVYHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEV 970 H +GV HRDLKPEN L D + LK DFG LS V+ D L+ G+ YVAPEV Sbjct: 268 HLQGVVHRDLKPENFLFKSKDEDSQLKAIDFG---LSDYVKPDERLNDIVGSAYYVAPEV 324 Query: 971 INNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKAD--FSCPSW--FSTS 1138 + ++ Y +AD+WS GVI ++L+ G PF +++ + KA+ F P W S+ Sbjct: 325 L-HRSY-STEADVWSIGVISYILLCGSRPFWARTESGIFRAVLKANLSFDEPPWPSVSSE 382 Query: 1139 AKKLIKKILDPNPNTRITIAEVINNEWFK 1225 AK +K++L+ +P R+T A+ + + W K Sbjct: 383 AKDFVKRLLNKDPRKRMTAAQALCHSWIK 411
>Q09170:CDS1_SCHPO Serine/threonine-protein kinase cds1 - Schizosaccharomyces pombe| (Fission yeast) Length = 460 Score = 177 bits (449), Expect = 1e-43 Identities = 99/270 (36%), Positives = 156/270 (57%), Gaps = 14/270 (5%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVL----KHKMIAQIKREISTMKLI 622 YE+ RTLG GTFA VK A V +G+ AIKI++K K+L + + +REI +K + Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSL 226 Query: 623 RHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCH 802 HP V++ +E+ + +++IVME V GG+L D + + G + E D + +QL+ + + H Sbjct: 227 HHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLH 286 Query: 803 SRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 +GV HRD+KPEN+L+ + LK+SDFGL+ + L T CGT Y+APEV+ +K Sbjct: 287 KQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGT--GTFLETFCGTMGYLAPEVLKSK 344 Query: 983 ------GYDGAKADLWSCGVILFVLMAGYLPFEDSN----LMALYKKIYKADFSCPSWFS 1132 GYD K D+WS G +L+V++ +PF S+ + + K Y + + S Sbjct: 345 NVNLDGGYDD-KVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEIS 403 Query: 1133 TSAKKLIKKILDPNPNTRITIAEVINNEWF 1222 LI ++L+ NP RI+ +E + + WF Sbjct: 404 EEGIDLINRMLEINPEKRISESEALQHPWF 433
>O54863:TSSK2_MOUSE Testis-specific serine/threonine-protein kinase 2 - Mus musculus| (Mouse) Length = 357 Score = 177 bits (448), Expect = 2e-43 Identities = 105/268 (39%), Positives = 153/268 (57%), Gaps = 4/268 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y +G LG+G++AKVK A + NVA+KI+D+ K + + RE+ + + H + Sbjct: 12 YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHRS 71 Query: 635 VIRMYEVM-ASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 +I+ YE+ S +IYIVMEL G+L I RG L ED K F+Q+ +AV YCH Sbjct: 72 IIKTYEIFETSDGRIYIVMELGVQGDLLTFIKCRGALHEDVGGKMFRQVSSAVKYCHDLD 131 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLS--ALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 V HRDLK ENLLLD + +K+SDFG S L L T CG+ Y APEV Sbjct: 132 VVHRDLKCENLLLDKDFNIKLSDFGFSKGCLRDGSGRIVLSKTFCGSAAYAAPEVRQGIP 191 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMAL-YKKIYKADFSCPSWFSTSAKKLIKKI 1162 Y D+WS GVIL++++ G +P++DS++ L +K ++ DF + K LI +I Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSDIKKLRIQKEHRVDFPRSKNLTGECKDLIYRI 251 Query: 1163 LDPNPNTRITIAEVINNEWFKKGYQPPR 1246 L P+ N R+ I E++++ W QPP+ Sbjct: 252 LQPDVNRRLHIDEILSHSWL----QPPK 275
>P27791:KAPCA_RAT cAMP-dependent protein kinase, alpha-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 177 bits (448), Expect = 2e-43 Identities = 94/257 (36%), Positives = 148/257 (57%), Gaps = 5/257 (1%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRM 646 +TLG G+F +V ++ E+G + A+KILDK KV+K K I E ++ + P ++++ Sbjct: 48 KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107 Query: 647 YEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRD 826 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RD Sbjct: 108 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167 Query: 827 LKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKAD 1006 LKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D Sbjct: 168 LKPENLLIDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VD 221 Query: 1007 LWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN---- 1174 W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281 Query: 1175 -PNTRITIAEVINNEWF 1222 N + + ++ N++WF Sbjct: 282 FGNLKNGVNDIKNHKWF 298
>Q9Z265:CHK2_MOUSE Serine/threonine-protein kinase Chk2 - Mus musculus (Mouse)| Length = 546 Score = 177 bits (448), Expect = 2e-43 Identities = 104/281 (37%), Positives = 155/281 (55%), Gaps = 15/281 (5%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVL-----KHKMIAQIKREISTMKL 619 Y + +TLG G +VK A +T + VAIKI+ K + + ++ EI +K Sbjct: 224 YIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEILKK 283 Query: 620 IRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYC 799 + HP +I++ +V + YIV+EL+ GGELFD++ RLKE + YF Q++ AV Y Sbjct: 284 LNHPCIIKIKDVFDAED-YYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYL 342 Query: 800 HSRGVYHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEV 970 H G+ HRDLKPEN+LL + + +K++DFG S + + E L+ T CGTP Y+APEV Sbjct: 343 HENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKI---LGETSLMRTLCGTPTYLAPEV 399 Query: 971 INNKGYDG--AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY---KADFSCPSW--F 1129 + + G G D WS GVILF+ ++GY PF + K K +F W Sbjct: 400 LVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWTDV 459 Query: 1130 STSAKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFE 1252 S A L+KK+L +P R+T E +N+ W + Y +F+ Sbjct: 460 SEEALDLVKKLLVVDPKARLTTEEALNHPWLQDEYMKKKFQ 500
>O01427:AIR2_CAEEL Aurora/Ipl1-related protein kinase 2 - Caenorhabditis elegans| Length = 305 Score = 177 bits (448), Expect = 2e-43 Identities = 91/257 (35%), Positives = 142/257 (55%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F V AR +VAIK+L K +++ + Q++REI + HPN Sbjct: 30 FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPN 89 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y KIY+V+E GGE++ ++ R E A KY ++ +A+ YCH + V Sbjct: 90 IIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYMYEIADALSYCHRKNV 149 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPENLL+ + G LK+ DFG S + + T CGT +Y+ PE++N + Sbjct: 150 IHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKR----QTMCGTMDYLPPEMVNGADHSD 205 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A DLW+ GV+ + + G PFE + Y I A F+ P A+ LI ++L + Sbjct: 206 A-VDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDLIGRLLVVD 264 Query: 1175 PNTRITIAEVINNEWFK 1225 P R T+ +V + W + Sbjct: 265 PKARCTLEQVKEHYWIQ 281
>P28178:PK2_DICDI Protein kinase 2 - Dictyostelium discoideum (Slime mold)| Length = 479 Score = 176 bits (447), Expect = 2e-43 Identities = 87/260 (33%), Positives = 149/260 (57%), Gaps = 3/260 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +EL +G+G+F KV + + A+K+L KD ++ K + K E + ++ I HP Sbjct: 153 FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPF 212 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ ++ ++ K+Y+V++ V GGELF + GR E + Y ++++A+D+ H + + Sbjct: 213 IVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDI 272 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPEN+LLD+ G + ++DFG LS+++ T CGTP Y+APEV+N G+ G Sbjct: 273 VYRDLKPENILLDSEGHICITDFG---LSKKIETTDGTFTFCGTPEYLAPEVLNGHGH-G 328 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 D WS G +L+ ++ G PF N+ +Y+KI + P++ S AK L++ +L Sbjct: 329 CAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLLEGLLTRE 388 Query: 1175 PNTRITI---AEVINNEWFK 1225 + R+ EV + WFK Sbjct: 389 VDKRLGTKGGGEVKQHPWFK 408
>Q6FV07:IPL1_CANGA Spindle assembly checkpoint kinase - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 358 Score = 176 bits (446), Expect = 3e-43 Identities = 88/258 (34%), Positives = 152/258 (58%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+GR LG+G F KV R+ ++G A+K ++K+++L+ ++ Q+KRE+ + HPN Sbjct: 100 FEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQLGMDHPN 159 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I++Y ++Y++ME GEL+ + + G + A Y Q+ +A+ Y H + + Sbjct: 160 IIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALHYMHKKRI 219 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPEN+L+ + +K++DFG S L+ E T CGT +Y++PE+I + YD Sbjct: 220 IHRDVKPENVLIGFDNVVKLADFGWSILNP---EGSKRKTLCGTIDYLSPEMITPREYD- 275 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+W+ GV+ + L+ G PFE+++ YK+I K D + P S AK LI K+L + Sbjct: 276 EQVDVWALGVLAYELVVGVPPFEENSKELTYKRILKCDLNFPESISKDAKDLISKLLVTD 335 Query: 1175 PNTRITIAEVINNEWFKK 1228 R+++ V + W K Sbjct: 336 TTQRLSLTGVKTHPWILK 353
>P08413:KCC2B_RAT Calcium/calmodulin-dependent protein kinase type II beta chain -| Rattus norvegicus (Rat) Length = 542 Score = 176 bits (445), Expect = 4e-43 Identities = 100/262 (38%), Positives = 152/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L +G+G F+ V+ + TG A KI++ K L + +++RE +L++H N Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKK-LSARDHQKLEREARICRLLKHSN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ AV +CH GV Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ + Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKEA 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 ++L NP RIT E + + W Sbjct: 250 NQMLTINPAKRITAHEALKHPW 271
>P28652:KCC2B_MOUSE Calcium/calmodulin-dependent protein kinase type II beta chain - Mus| musculus (Mouse) Length = 542 Score = 176 bits (445), Expect = 4e-43 Identities = 100/262 (38%), Positives = 152/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L +G+G F+ V+ + TG A KI++ K L + +++RE +L++H N Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKK-LSARDHQKLEREARICRLLKHSN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ AV +CH GV Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ + Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKEA 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 ++L NP RIT E + + W Sbjct: 250 NQMLTINPAKRITAHEALKHPW 271
>Q13554:KCC2B_HUMAN Calcium/calmodulin-dependent protein kinase type II beta chain - Homo| sapiens (Human) Length = 664 Score = 176 bits (445), Expect = 4e-43 Identities = 100/262 (38%), Positives = 152/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L +G+G F+ V+ + TG A KI++ K L + +++RE +L++H N Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKK-LSARDHQKLEREARICRLLKHSN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ AV +CH GV Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ + Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKEA 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 ++L NP RIT E + + W Sbjct: 250 NQMLTINPAKRITAHEALKHPW 271
>Q6C3J2:IPL1_YARLI Spindle assembly checkpoint kinase - Yarrowia lipolytica (Candida| lipolytica) Length = 371 Score = 176 bits (445), Expect = 4e-43 Identities = 85/256 (33%), Positives = 148/256 (57%), Gaps = 1/256 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+G+ LG+G F KV ++ +TG A+K ++K ++++ + Q +RE+ +RH N Sbjct: 99 FEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQSNLRHTN 158 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+R++ + ++Y+++E V GEL+ + ++ R E A Y Q+ A+ Y H + + Sbjct: 159 VLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHGKNI 218 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPEN+LL N T+K+SDFG S + R T CGT +Y+ PE++ ++ YD Sbjct: 219 IHRDIKPENILLHFNDTIKISDFGWSVHAPSNRRS----TLCGTMDYLPPEIVQSRPYD- 273 Query: 995 AKADLWSCGVILFVLMAGYLPFED-SNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 D+WS G++++ + G PFE+ A Y++I K D P + S A LIK++L Sbjct: 274 KNVDVWSLGILMYEFLCGAPPFEEPGGAQATYRRIVKLDLRIPPYVSADAADLIKRMLTL 333 Query: 1172 NPNTRITIAEVINNEW 1219 +P R + ++ + W Sbjct: 334 DPAKRFKLKDMHKHPW 349
>Q8IBS5:CDPK4_PLAF7 Calcium-dependent protein kinase 4 - Plasmodium falciparum (isolate| 3D7) Length = 528 Score = 176 bits (445), Expect = 4e-43 Identities = 125/395 (31%), Positives = 197/395 (49%), Gaps = 11/395 (2%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRM 646 + LG+G+F +V +R+ TG AIK++ K V + + RE+ +K++ H N++++ Sbjct: 74 KILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDHINIMKL 133 Query: 647 YEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRD 826 YE Y+V ++ TGGELFD+I SR R E DA + +Q+++ + Y H V HRD Sbjct: 134 YEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITYMHKNNVVHRD 193 Query: 827 LKPENLLLDANG----TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 LKPEN+LL+ +K+ DFGLS + ++ + GT Y+AP+V++ YD Sbjct: 194 LKPENILLETKNKEDMIIKIIDFGLSTHFEYSKK---MKDKIGTAYYIAPDVLHGT-YD- 248 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKLIKKI 1162 K D+WSCGVIL++L++G PF SN + KK+ K F P + S AK LIKK+ Sbjct: 249 EKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVEAGKYTFDLPQFKKISDKAKDLIKKM 308 Query: 1163 LDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLD-DINSIFNESGDPAQLVVERREE 1339 L RI+ + + +EW K T++ NL+ DI S+ +L + + Sbjct: 309 LMYTSAVRISARDALEHEWIK-------MMTSKDNLNIDIPSL--------ELSIANIRQ 353 Query: 1340 RPAVMNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAAAGPMGFNV 1519 + + G L T+ D K T+ ++ N G + N Sbjct: 354 FQSTQKLAQAALLYMGSKLTTI-----DETKELTKIFKKMDKN--------GDGQLDRNE 400 Query: 1520 QKRNYK--LKLQGENPGRKGQLAIATEVFEVTPSL 1618 YK LKL+GE+ AI EV ++ S+ Sbjct: 401 LIIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSI 435
>P22694:KAPCB_HUMAN cAMP-dependent protein kinase, beta-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 175 bits (443), Expect = 7e-43 Identities = 94/261 (36%), Positives = 148/261 (56%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ T + A+KILDK KV+K K I E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + ++++ ++WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P24256:KAPB2_BOVIN cAMP-dependent protein kinase, beta-2-catalytic subunit - Bos taurus| (Bovine) Length = 397 Score = 175 bits (443), Expect = 7e-43 Identities = 94/261 (36%), Positives = 148/261 (56%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ T + A+KILDK KV+K K I E ++ + P Sbjct: 90 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 149 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 150 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 209 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 210 IYRDLKPENLLIDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 264 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 265 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 323 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + ++++ ++WF Sbjct: 324 LTKRFGNLKNGVSDIKTHKWF 344
>P05131:KAPB1_BOVIN cAMP-dependent protein kinase, beta-1-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 175 bits (443), Expect = 7e-43 Identities = 94/261 (36%), Positives = 148/261 (56%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ T + A+KILDK KV+K K I E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + ++++ ++WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>O59697:PPK25_SCHPO Serine/threonine-protein kinase ppk25 - Schizosaccharomyces pombe| (Fission yeast) Length = 423 Score = 174 bits (442), Expect = 9e-43 Identities = 94/255 (36%), Positives = 149/255 (58%), Gaps = 1/255 (0%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRM 646 +T+G G+ KVK N+ TGE A+K++ + + +++RE +L+RHPN+ R+ Sbjct: 57 KTIGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTV-RVQREALLGRLLRHPNICRV 115 Query: 647 YEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRD 826 + + + YI+ E V GG+L + I +RG+L ED AR + QLINA+ Y H + HRD Sbjct: 116 IDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYLHKNFIVHRD 175 Query: 827 LKPENLLLDANGT-LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 1003 LK EN+LL + +K+ DFGLS + D LL T CG+ + APE+++ K Y G + Sbjct: 176 LKIENVLLTQDSRQVKLIDFGLSNFYSK---DDLLRTYCGSLYFAAPELLDAKPYIGPEV 232 Query: 1004 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNT 1183 D+WS GV+++V++ G +PF+D ++ L+ KI PS+ S LI +L+ NP Sbjct: 233 DVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPSYISEDCCSLIAAMLNVNPRK 292 Query: 1184 RITIAEVINNEWFKK 1228 R ++ + W KK Sbjct: 293 RCSLEQAAKFPWLKK 307
>P13186:KIN2_YEAST Serine/threonine-protein kinase KIN2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1147 Score = 174 bits (442), Expect = 9e-43 Identities = 94/286 (32%), Positives = 157/286 (54%), Gaps = 26/286 (9%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDK-DKVLKHKM----------------- 580 +E T+G G+ KVK ++ +T E IKI+++ K HK Sbjct: 99 WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQK 158 Query: 581 -----IAQIKR---EISTMKLIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRG 736 IA+ KR E S +++ HP++ R++E+ Y++ E V+GG+L D I G Sbjct: 159 RLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHG 218 Query: 737 RLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVRE 916 LKE ARK+ + + +A+ Y H+ + HRDLK EN+++ ++G +K+ DFGLS + ++ Sbjct: 219 SLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQ 278 Query: 917 DGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKI 1096 LHT CG+ + APE++ + Y G + D+WS G++L+VL+ G +PF+D N L++KI Sbjct: 279 ---LHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKI 335 Query: 1097 YKADFSCPSWFSTSAKKLIKKILDPNPNTRITIAEVINNEWFKKGY 1234 K PS S L+ +++ +P R T+ V+ + W +GY Sbjct: 336 KKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGY 381
>P08414:KCC4_MOUSE Calcium/calmodulin-dependent protein kinase type IV - Mus musculus| (Mouse) Length = 469 Score = 174 bits (442), Expect = 9e-43 Identities = 103/288 (35%), Positives = 161/288 (55%), Gaps = 11/288 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDK--DKVLKHKMIAQIKREISTMKLIRH 628 +E+ LG G + V + T + A+K+L K DK + ++ EI + + H Sbjct: 42 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-------VRTEIGVLLRLSH 94 Query: 629 PNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSR 808 PN+I++ E+ + T+I +V+ELVTGGELFD+I +G E DAR +Q++ AV Y H Sbjct: 95 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAVAYLHEN 154 Query: 809 GVYHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINN 979 G+ HRDLKPENLL + LK++DFGLS + V L+ T CGTP Y APE++ Sbjct: 155 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKI---VEHQVLMKTVCGTPGYCAPEILRG 211 Query: 980 KGYDGAKADLWSCGVILFVLMAGYLPFEDS-NLMALYKKIYKAD--FSCPSW--FSTSAK 1144 Y G + D+WS G+I ++L+ G+ PF D ++++I + F P W S +AK Sbjct: 212 CAY-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAK 270 Query: 1145 KLIKKILDPNPNTRITIAEVINNEWFK-KGYQPPRFETAEVNLDDINS 1285 L+KK++ +P R+T + + + W K +TA+ L + N+ Sbjct: 271 DLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNA 318
>P68182:KAPCB_RAT cAMP-dependent protein kinase, beta-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 174 bits (441), Expect = 1e-42 Identities = 94/261 (36%), Positives = 148/261 (56%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ T + A+KILDK KV+K K I E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + ++++ ++WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P68181:KAPCB_MOUSE cAMP-dependent protein kinase, beta-catalytic subunit - Mus musculus| (Mouse) Length = 351 Score = 174 bits (441), Expect = 1e-42 Identities = 94/261 (36%), Positives = 148/261 (56%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ T + A+KILDK KV+K K I E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + ++++ ++WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P68180:KAPCB_CRIGR cAMP-dependent protein kinase, beta-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 174 bits (441), Expect = 1e-42 Identities = 94/261 (36%), Positives = 148/261 (56%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ T + A+KILDK KV+K K I E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + ++++ ++WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P05383:KAPCB_PIG cAMP-dependent protein kinase, beta-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 174 bits (440), Expect = 2e-42 Identities = 94/261 (36%), Positives = 148/261 (56%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ T + A+KILDK KV+K K I E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + Sbjct: 104 LVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L + Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + ++++ ++WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>Q6BVA0:IPL1_DEBHA Spindle assembly checkpoint kinase - Debaryomyces hansenii (Yeast)| (Torulaspora hansenii) Length = 412 Score = 174 bits (440), Expect = 2e-42 Identities = 88/261 (33%), Positives = 145/261 (55%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+G+ LG+G KV ++ +G A+K++ K ++ K+ +REI + HP Sbjct: 148 FEIGKVLGKGKLGKVYCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIEIQSNLIHPK 207 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 + R+Y +Y+++E GEL+ + + R + A Y Q+ A+DY H++ + Sbjct: 208 ISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALDYLHTKHI 267 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRD+KPEN+LL + +K+SDFG S S L T CGT +Y+ PE+I + +D Sbjct: 268 IHRDIKPENILLSTDNCIKLSDFGWSVKSLPSSSTKRL-TICGTLDYLPPEMIESNEHD- 325 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 D+WS G++ + + G PFE+ + + YK+I K D PS+ S+ A LI ++L + Sbjct: 326 YTVDIWSLGILCYEFLVGKPPFEEIDKNSTYKRIAKVDLKIPSFLSSEATDLILRLLQKS 385 Query: 1175 PNTRITIAEVINNEWFKKGYQ 1237 P RIT+AEV+N+ W Q Sbjct: 386 PKKRITLAEVMNHPWIMNNQQ 406
>P39009:DUN1_YEAST DNA damage response protein kinase DUN1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 513 Score = 174 bits (440), Expect = 2e-42 Identities = 99/285 (34%), Positives = 161/285 (56%), Gaps = 29/285 (10%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y LG+ LG G +A VK A+N +TG+ VA+KI + K Q + E + + ++HPN Sbjct: 200 YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPN 259 Query: 635 VIRMYE-----VMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYC 799 ++ + + + S+ + Y+V+E + GELF++I + L++D+++ F+QL+ + Y Sbjct: 260 IVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYL 319 Query: 800 HSRGVYHRDLKPENLLL-------------------DANGTLKVSDFGLSALSQQVREDG 922 H + + HRD+KPEN+LL + + +K++DFGL+ + +++ Sbjct: 320 HEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQ--- 376 Query: 923 LLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDS-NLMALYKKIY 1099 +T CGTP+YVAPEV+ KGY +K DLWS GVIL+V + G+ PF D +L ++I Sbjct: 377 FTNTLCGTPSYVAPEVLTKKGYT-SKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQIL 435 Query: 1100 KAD--FSCPSW--FSTSAKKLIKKILDPNPNTRITIAEVINNEWF 1222 +A F P W S LI +L NP+ R I E +N+ WF Sbjct: 436 QAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWF 480
>Q96PN8:TSSK3_HUMAN Testis-specific serine/threonine-protein kinase 3 - Homo sapiens| (Human) Length = 268 Score = 173 bits (439), Expect = 2e-42 Identities = 102/259 (39%), Positives = 160/259 (61%), Gaps = 4/259 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+LG+T+GEGT++KVK A + + VAIK++DK + + + RE+ ++ + H N Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 635 VIRMYEVMASRT-KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 +I++YE++ S KI +VMEL GG++FD + + G L E A+ F+Q++ A+ YCH G Sbjct: 70 IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLS-ALSQQVREDGLLHTTCGTPNYVAPEVINNKGY 988 V HRDLK EN LL LK++DFG + L + RE L T CG+ Y APEV+ + Sbjct: 130 VAHRDLKCENALLQ-GFNLKLTDFGFAKVLPKSHRE--LSQTFCGSTAYAAPEVLQGIPH 186 Query: 989 DGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSA--KKLIKKI 1162 D K D+WS GV+L+V++ LPF+D+++ + + K S P+ S SA + L+K++ Sbjct: 187 DSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKG-VSFPTHLSISADCQDLLKRL 245 Query: 1163 LDPNPNTRITIAEVINNEW 1219 L+P+ R +I EV + W Sbjct: 246 LEPDMILRPSIEEVSWHPW 264
>Q9H4B4:PLK3_HUMAN Serine/threonine-protein kinase PLK3 - Homo sapiens (Human)| Length = 646 Score = 173 bits (439), Expect = 2e-42 Identities = 94/264 (35%), Positives = 150/264 (56%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G FA+ A + ETG A+K++ + +V K +I EI + ++H + Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH 121 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R IYI +EL + L +R L E + R Y +Q+++ + Y H RG+ Sbjct: 122 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 181 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK N + N LKV DFGL+A + + T CGTPNYVAPEV+ +G+ G Sbjct: 182 LHRDLKLGNFFITENMELKVGDFGLAARLEPPEQ--RKKTICGTPNYVAPEVLLRQGH-G 238 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 +AD+WS G +++ L+ G PFE ++L Y+ I + ++ P+ S A++L+ IL + Sbjct: 239 PEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRAS 298 Query: 1175 PNTRITIAEVINNEWFKKGYQPPR 1246 P R +I +++ +++F KGY P R Sbjct: 299 PRDRPSIDQILRHDFFTKGYTPDR 322
>Q3MHJ9:KCC2B_BOVIN Calcium/calmodulin-dependent protein kinase type II beta chain - Bos| taurus (Bovine) Length = 542 Score = 173 bits (439), Expect = 2e-42 Identities = 99/262 (37%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L +G+G F+ V+ + TG A KI++ K L + +++RE +L++H N Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKK-LSARDHQKLEREARICRLLKHSN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ AV +CH GV Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ + Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKEA 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 ++L NP RI E + + W Sbjct: 250 NQMLTINPAKRIMAHEALKHPW 271
>O00444:PLK4_HUMAN Serine/threonine-protein kinase PLK4 - Homo sapiens (Human)| Length = 970 Score = 173 bits (438), Expect = 3e-42 Identities = 84/259 (32%), Positives = 152/259 (58%), Gaps = 1/259 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +++G LG+G+FA V A ++ TG VAIK++DK + K M+ +++ E+ ++HP+ Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGR-LKEDDARKYFQQLINAVDYCHSRG 811 ++ +Y +Y+V+E+ GE+ + +R + E++AR + Q+I + Y HS G Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG 131 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 991 + HRDL NLLL N +K++DFGL+ + E +T CGTPNY++PE+ + Sbjct: 132 ILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKH--YTLCGTPNYISPEIATRSAH- 188 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 G ++D+WS G + + L+ G PF+ + K+ AD+ P++ S AK LI ++L Sbjct: 189 GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLRR 248 Query: 1172 NPNTRITIAEVINNEWFKK 1228 NP R++++ V+++ + + Sbjct: 249 NPADRLSLSSVLDHPFMSR 267
>P53350:PLK1_HUMAN Serine/threonine-protein kinase PLK1 - Homo sapiens (Human)| Length = 603 Score = 173 bits (438), Expect = 3e-42 Identities = 111/322 (34%), Positives = 166/322 (51%), Gaps = 16/322 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G FAK + +T E A KI+ K +LK ++ EIS + + H + Sbjct: 53 YVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQH 112 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+ + +++V+EL L + R L E +AR Y +Q++ Y H V Sbjct: 113 VVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRV 172 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDG-LLHTTCGTPNYVAPEVINNKGYD 991 HRDLK NL L+ + +K+ DFGL+ +V DG T CGTPNY+APEV++ KG+ Sbjct: 173 IHRDLKLGNLFLNEDLEVKIGDFGLAT---KVEYDGERKKTLCGTPNYIAPEVLSKKGH- 228 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 + D+WS G I++ L+ G PFE S L Y +I K ++S P + A LI+K+L Sbjct: 229 SFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQT 288 Query: 1172 NPNTRITIAEVINNEWFKKGY-----------QPPRFETAEVNLDDIN----SIFNESGD 1306 +P R TI E++N+E+F GY PPRF A +LD N ++ N+ + Sbjct: 289 DPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGLE 348 Query: 1307 PAQLVVERREERPAVMNAFELI 1372 R +E P V E++ Sbjct: 349 NPLPERPREKEEPVVRETGEVV 370
>Q0GGW5:STK11_CHICK Serine/threonine protein kinase 11 - Gallus gallus (Chicken)| Length = 440 Score = 172 bits (437), Expect = 3e-42 Identities = 97/264 (36%), Positives = 152/264 (57%), Gaps = 6/264 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLK-HKMIAQIKREISTMKLIRHP 631 Y +G LGEG++ KVK + ET A+KIL K K+ + A +K+EI ++ +RH Sbjct: 49 YLMGDLLGEGSYGKVKEMLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108 Query: 632 NVIRMYEVMAS--RTKIYIVMELVTGG--ELFDKIASRGRLKEDDARKYFQQLINAVDYC 799 NVI++ +V+ + + K+Y+VME G E+ D + + R A YF QLI+ ++Y Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK-RFPVFQAHGYFCQLIDGLEYL 167 Query: 800 HSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINN 979 HS+G+ H+D+KP NLLL NGTLK+SD G++ ED T+ G+P + PE+ N Sbjct: 168 HSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAEDDTCRTSQGSPAFQPPEIANG 227 Query: 980 -KGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIK 1156 + G K D+WS GV L+ + G PFE N+ L++ I K DF+ P L++ Sbjct: 228 LDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGDFTIPEDCGPPLSDLLR 287 Query: 1157 KILDPNPNTRITIAEVINNEWFKK 1228 +L+ +P R +I ++ + WF+K Sbjct: 288 GMLEYDPAKRFSIQQIRQHNWFRK 311
>P13234:KCC4_RAT Calcium/calmodulin-dependent protein kinase type IV - Rattus| norvegicus (Rat) Length = 474 Score = 172 bits (436), Expect = 4e-42 Identities = 102/288 (35%), Positives = 160/288 (55%), Gaps = 11/288 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDK--DKVLKHKMIAQIKREISTMKLIRH 628 +E+ LG G + V + T + A+K+L K DK + ++ EI + + H Sbjct: 42 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-------VRTEIGVLLRLSH 94 Query: 629 PNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSR 808 PN+I++ E+ + T+I +V+ELVTGGELFD+I +G E DA +Q++ AV Y H Sbjct: 95 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 154 Query: 809 GVYHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINN 979 G+ HRDLKPENLL + LK++DFGLS + V L+ T CGTP Y APE++ Sbjct: 155 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKI---VEHQVLMKTVCGTPGYCAPEILRG 211 Query: 980 KGYDGAKADLWSCGVILFVLMAGYLPFEDS-NLMALYKKIYKAD--FSCPSW--FSTSAK 1144 Y G + D+WS G+I ++L+ G+ PF D ++++I + F P W S +AK Sbjct: 212 CAY-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAK 270 Query: 1145 KLIKKILDPNPNTRITIAEVINNEWFK-KGYQPPRFETAEVNLDDINS 1285 L+KK++ +P R+T + + + W K +TA+ L + N+ Sbjct: 271 DLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNA 318
>Q64702:PLK4_MOUSE Serine/threonine-protein kinase PLK4 - Mus musculus (Mouse)| Length = 925 Score = 172 bits (435), Expect = 6e-42 Identities = 84/263 (31%), Positives = 151/263 (57%), Gaps = 1/263 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +++G LG+G+FA V A ++ TG VAIK++DK + K M+ +++ E+ ++HP+ Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGR-LKEDDARKYFQQLINAVDYCHSRG 811 V+ +Y +Y+V+E+ GE+ + +R + E +AR + Q+I + Y HS G Sbjct: 72 VLELYNYFEDNNYVYLVLEMCHNGEMNRYLKNRMKPFSEREARHFMHQIITGMLYLHSHG 131 Query: 812 VYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 991 + HRDL N+LL N +K++DFGL+ E +T CGTPNY++PE+ + Sbjct: 132 ILHRDLTLSNILLTRNMNIKIADFGLATQLNMPHEKH--YTLCGTPNYISPEIATRSAH- 188 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 G ++D+WS G + + L+ G PF+ + K+ AD+ P++ S A+ LI ++L Sbjct: 189 GLESDIWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPAFLSREAQDLIHQLLRR 248 Query: 1172 NPNTRITIAEVINNEWFKKGYQP 1240 NP R++++ V+++ + + P Sbjct: 249 NPADRLSLSSVLDHPFMSRNPSP 271
>P28582:CDPK_DAUCA Calcium-dependent protein kinase - Daucus carota (Carrot)| Length = 532 Score = 172 bits (435), Expect = 6e-42 Identities = 103/267 (38%), Positives = 148/267 (55%), Gaps = 8/267 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMK-LIRHP 631 Y LG+ LG G F V +G+ A K + K K++ IKREI ++ L P Sbjct: 81 YTLGKELGRGQFGCVYQCTENSSGQLYACKSILKRKLVSKNDKEDIKREIQILQHLSGQP 140 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 N++ V R +++VMEL GGELFD+I ++G E A +Q++N V CH G Sbjct: 141 NIVEFKGVFEDRQSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVVHVCHFMG 200 Query: 812 VYHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 V HRDLKPEN LL D + LK +DFGLS + E + G+ YVAPEV+ + Sbjct: 201 VMHRDLKPENFLLSSKDKDAMLKATDFGLSVF---IEEGKVYRNIVGSAYYVAPEVL-RR 256 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKL 1150 Y G + D+WS GVIL++L++G PF N ++ I + DF W S SAK L Sbjct: 257 SY-GKEIDIWSAGVILYILLSGVPPFWAENEKGIFDAILEGVIDFESEPWPSVSNSAKDL 315 Query: 1151 IKKILDPNPNTRITIAEVINNEWFKKG 1231 ++K+L +P RIT A+V+++ W ++G Sbjct: 316 VRKMLTQDPRRRITSAQVLDHPWMREG 342
>Q60806:PLK3_MOUSE Serine/threonine-protein kinase PLK3 - Mus musculus (Mouse)| Length = 631 Score = 171 bits (434), Expect = 8e-42 Identities = 93/264 (35%), Positives = 150/264 (56%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G FA+ A + E+G A+K++ + +V K +I EI + ++H + Sbjct: 63 YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH 122 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R IYI +EL + L +R L E + R Y +Q+++ + Y H RG+ Sbjct: 123 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 182 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK N + N LKV DFGL+A + + T CGTPNYVAPEV+ +G+ G Sbjct: 183 LHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQ--RKKTICGTPNYVAPEVLLRQGH-G 239 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 +AD+WS G +++ L+ G PFE ++L Y+ I + ++ P+ S A++L+ IL + Sbjct: 240 PEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRAS 299 Query: 1175 PNTRITIAEVINNEWFKKGYQPPR 1246 P R +I +++ +++F KGY P R Sbjct: 300 PRDRPSIEQILRHDFFTKGYTPDR 323
>Q5F3L1:KS6A5_CHICK Ribosomal protein S6 kinase alpha-5 - Gallus gallus (Chicken)| Length = 789 Score = 171 bits (434), Expect = 8e-42 Identities = 104/279 (37%), Positives = 162/279 (58%), Gaps = 18/279 (6%) Frame = +2 Query: 455 YELG---RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIR 625 YEL + LGEG+F+ + + +T + A+KI+ K +M A +REI+ +KL Sbjct: 413 YELDLKEKPLGEGSFSICRKCLHKKTSQEYAVKIISK------RMEANTQREITALKLCE 466 Query: 626 -HPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCH 802 HPNV++++EV + ++VMEL+ GGEL ++I + E +A ++L++AV + H Sbjct: 467 GHPNVVKLHEVYHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRLVSAVSHMH 526 Query: 803 SRGVYHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI 973 GV HRDLKPENLL N +K+ DFG + L ++ L T C T +Y APE+ Sbjct: 527 DVGVVHRDLKPENLLFTDETDNSEIKIIDFGFARLKPP--DNQPLKTPCFTLHYAAPELF 584 Query: 974 NNKGYDGAKADLWSCGVILFVLMAGYLPFED-------SNLMALYKKIYKADFSC--PSW 1126 N+ GYD DLWS GVIL+ +++G +PF+ ++ + + KKI K +FS +W Sbjct: 585 NHNGYD-ESCDLWSLGVILYTMLSGQVPFQSQDKSLTCTSALEIMKKIKKGEFSFEGEAW 643 Query: 1127 --FSTSAKKLIKKILDPNPNTRITIAEVINNEWFKKGYQ 1237 S AK+LI+ +L +PN RI ++ + NEW + G Q Sbjct: 644 KNVSEEAKELIQGLLTVDPNKRIKMSSLRYNEWLQDGSQ 682 Score = 132 bits (332), Expect = 5e-30 Identities = 77/256 (30%), Positives = 148/256 (57%), Gaps = 11/256 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNV---ETGENVAIKILDKDKVL-KHKMIAQIKREISTMKLI 622 +EL + LG G + KV R V + G+ A+K+L K ++ K K + E ++ I Sbjct: 39 FELLKVLGTGAYGKVFLVRKVSGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHI 98 Query: 623 RH-PNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYC 799 R P ++ ++ + TK++++++ + GGELF ++ R R E++ + Y +++ A+++ Sbjct: 99 RQSPFLVTLHYAFQTDTKLHLILDYINGGELFTHLSQRERFSENEVQIYIGEIVLALEHL 158 Query: 800 HSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI-- 973 H G+ +RD+K EN+LLD++G + ++DFGLS E+ ++ CGT Y+AP+++ Sbjct: 159 HKLGIIYRDIKLENILLDSDGHVVLTDFGLSK-EFLTDENERAYSFCGTIEYMAPDIVRG 217 Query: 974 NNKGYDGAKADLWSCGVILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSWFSTSA 1141 + G+D A D WS GV+++ L+ G PF E ++ + ++I K++ P S + Sbjct: 218 GDTGHDKA-VDWWSVGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALS 276 Query: 1142 KKLIKKILDPNPNTRI 1189 K +I+++L +P R+ Sbjct: 277 KDIIQRLLMKDPKKRL 292
>Q39030:KPK19_ARATH Serine/threonine-protein kinase AtPK19 - Arabidopsis thaliana| (Mouse-ear cress) Length = 471 Score = 171 bits (434), Expect = 8e-42 Identities = 87/262 (33%), Positives = 154/262 (58%), Gaps = 5/262 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+ + +G+G F KV R +T E A+K++ KDK+++ +K E + I HP Sbjct: 140 FEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPF 199 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++ ++ ++Y+V++ + GG LF ++ +G +ED AR Y ++++AV + H +G+ Sbjct: 200 IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 259 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPEN+L+D +G + ++DFG L+++ E+ ++ CGT Y+APE++ KG+D Sbjct: 260 MHRDLKPENILMDVDGHVMLTDFG---LAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDK 316 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A AD WS G++L+ ++ G PF S + +KI K P + S A L+K +L Sbjct: 317 A-ADWWSVGILLYEMLTGKPPFLGSK-GKIQQKIVKDKIKLPQFLSNEAHALLKGLLQKE 374 Query: 1175 PNTRI-----TIAEVINNEWFK 1225 P R+ E+ ++WFK Sbjct: 375 PERRLGSGPSGAEEIKKHKWFK 396
>P13185:KIN1_YEAST Protein kinase KIN1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1064 Score = 171 bits (434), Expect = 8e-42 Identities = 93/289 (32%), Positives = 155/289 (53%), Gaps = 26/289 (8%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDK-DKVLKHK--MIAQIK---------- 595 +E T+G G+ KVK A++ T E A+KI+++ K HK M+ K Sbjct: 120 WEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQK 179 Query: 596 -------------REISTMKLIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRG 736 RE S +++ HP++ R++E+ Y++ E V+GG+L D I G Sbjct: 180 KLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHG 239 Query: 737 RLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVRE 916 ++E ARK+ + + +A+ Y H+ + HRDLK EN+++ + +K+ DFGLS + ++ Sbjct: 240 SIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQ 299 Query: 917 DGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKI 1096 LHT CG+ + APE++ Y G + D+WS GV+LFVL+ G +PF+D N L++KI Sbjct: 300 ---LHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKI 356 Query: 1097 YKADFSCPSWFSTSAKKLIKKILDPNPNTRITIAEVINNEWFKKGYQPP 1243 + P S L+ K+L +P R T+ +V+ + W +G+ P Sbjct: 357 KQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVRGFNGP 405
>P42818:KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 - Arabidopsis thaliana| (Mouse-ear cress) Length = 465 Score = 171 bits (433), Expect = 1e-41 Identities = 90/275 (32%), Positives = 158/275 (57%), Gaps = 5/275 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+ + +G+G F KV R ET E A+K++ KD +++ +K E + I HP Sbjct: 134 FEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPF 193 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++ ++ ++Y+V++ + GG LF ++ +G +ED AR Y ++++AV + H +G+ Sbjct: 194 IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 253 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLKPEN+L+D +G + ++DFG L+++ E+ ++ CGT Y+APE++ KG+D Sbjct: 254 MHRDLKPENILMDTDGHVMLTDFG---LAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDK 310 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A AD WS G++L+ ++ G PF S + +KI K P + S A ++K +L Sbjct: 311 A-ADWWSVGILLYEMLTGKPPFLGSK-GKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKE 368 Query: 1175 PNTRI-----TIAEVINNEWFKKGYQPPRFETAEV 1264 P R+ E+ ++WF KG + E EV Sbjct: 369 PERRLGSGLSGAEEIKQHKWF-KGINWKKLEAREV 402
>Q16566:KCC4_HUMAN Calcium/calmodulin-dependent protein kinase type IV - Homo sapiens| (Human) Length = 473 Score = 171 bits (433), Expect = 1e-41 Identities = 101/288 (35%), Positives = 160/288 (55%), Gaps = 11/288 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDK--DKVLKHKMIAQIKREISTMKLIRH 628 +E+ LG G + V + T + A+K+L K DK + ++ EI + + H Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-------VRTEIGVLLRLSH 98 Query: 629 PNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSR 808 PN+I++ E+ + T+I +V+ELVTGGELFD+I +G E DA +Q++ AV Y H Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158 Query: 809 GVYHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINN 979 G+ HRDLKPENLL + LK++DFGLS + V L+ T CGTP Y APE++ Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKI---VEHQVLMKTVCGTPGYCAPEILRG 215 Query: 980 KGYDGAKADLWSCGVILFVLMAGYLPFEDS-NLMALYKKIYKAD--FSCPSW--FSTSAK 1144 Y G + D+WS G+I ++L+ G+ PF D ++++I + F P W S +AK Sbjct: 216 CAY-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAK 274 Query: 1145 KLIKKILDPNPNTRITIAEVINNEWFK-KGYQPPRFETAEVNLDDINS 1285 L++K++ +P R+T + + + W K +TA+ L + N+ Sbjct: 275 DLVRKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNA 322
>P12370:KAPC_DROME cAMP-dependent protein kinase catalytic subunit - Drosophila| melanogaster (Fruit fly) Length = 353 Score = 171 bits (433), Expect = 1e-41 Identities = 93/261 (35%), Positives = 147/261 (56%), Gaps = 5/261 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E +TLG G+F +V ++ T + A+KILDK KV+K K + E ++ I+ P Sbjct: 46 FERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPF 105 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + + +Y+V+E V GGE+F + GR E +R Y Q++ A +Y H + Sbjct: 106 LVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDL 165 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 +RDLKPENLL+D+ G LKV+DFG + R G T CGTP Y+APE+I +KGY+ Sbjct: 166 IYRDLKPENLLIDSQGYLKVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNK 220 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 A D W+ GV+++ + AGY PF + +Y+KI PS F + K L++ +L + Sbjct: 221 A-VDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVD 279 Query: 1175 -----PNTRITIAEVINNEWF 1222 N + + ++ N +WF Sbjct: 280 LTKRYGNLKAGVNDIKNQKWF 300
>Q7RJG2:CDPK4_PLAYO Calcium-dependent protein kinase 4 - Plasmodium yoelii yoelii| Length = 528 Score = 171 bits (433), Expect = 1e-41 Identities = 121/395 (30%), Positives = 198/395 (50%), Gaps = 11/395 (2%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRM 646 + LG+G+F +V +++ TG AIK++ K V + + RE+ +K++ H N++++ Sbjct: 74 KILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIMKL 133 Query: 647 YEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRD 826 YE Y+V ++ +GGELFD+I SR R E DA + +Q+++ + Y H V HRD Sbjct: 134 YEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVHRD 193 Query: 827 LKPENLLLDANG----TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 LKPEN+LL+ +K+ DFGLS + ++ + GT Y+AP+V++ YD Sbjct: 194 LKPENILLETKNKEDMIIKIIDFGLSTHFEYSKK---MKDKIGTAYYIAPDVLHGT-YD- 248 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKLIKKI 1162 K D+WSCGVIL++L++G PF SN + KK+ K F P + S AK LIKK+ Sbjct: 249 EKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAKDLIKKM 308 Query: 1163 LDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLD-DINSIFNESGDPAQLVVERREE 1339 L RI+ + + +EW R T++ N++ DI S+ +L + ++ Sbjct: 309 LMYTSAVRISARDALEHEWI-------RLMTSKDNVNIDIPSL--------ELSITNIKQ 353 Query: 1340 RPAVMNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAAAGPMGFNV 1519 + + G L T+ D K T+ ++ N G + N Sbjct: 354 FQSTQKLAQAALLYMGSKLTTI-----DETKELTKIFKKMDKN--------GDGQLDRNE 400 Query: 1520 QKRNYK--LKLQGENPGRKGQLAIATEVFEVTPSL 1618 YK LKL+G++ AI EV ++ S+ Sbjct: 401 LIIGYKELLKLKGDDTTDLDNAAIEVEVDQILSSI 435
>P62345:CDPK4_PLABA Calcium-dependent protein kinase 4 - Plasmodium berghei (strain Anka)| Length = 528 Score = 171 bits (433), Expect = 1e-41 Identities = 121/395 (30%), Positives = 198/395 (50%), Gaps = 11/395 (2%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRM 646 + LG+G+F +V +++ TG AIK++ K V + + RE+ +K++ H N++++ Sbjct: 74 KILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIMKL 133 Query: 647 YEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRD 826 YE Y+V ++ +GGELFD+I SR R E DA + +Q+++ + Y H V HRD Sbjct: 134 YEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVHRD 193 Query: 827 LKPENLLLDANG----TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 LKPEN+LL+ +K+ DFGLS + ++ + GT Y+AP+V++ YD Sbjct: 194 LKPENILLETKNKEDMIIKIIDFGLSTHFEYSKK---MKDKIGTAYYIAPDVLHGT-YD- 248 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKLIKKI 1162 K D+WSCGVIL++L++G PF SN + KK+ K F P + S AK LIKK+ Sbjct: 249 EKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAKDLIKKM 308 Query: 1163 LDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLD-DINSIFNESGDPAQLVVERREE 1339 L RI+ + + +EW R T++ N++ DI S+ +L + ++ Sbjct: 309 LMYTSAVRISARDALEHEWI-------RLMTSKDNVNIDIPSL--------ELSITNIKQ 353 Query: 1340 RPAVMNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAAAGPMGFNV 1519 + + G L T+ D K T+ ++ N G + N Sbjct: 354 FQSTQKLAQAALLYMGSKLTTI-----DETKELTKIFKKMDKN--------GDGQLDRNE 400 Query: 1520 QKRNYK--LKLQGENPGRKGQLAIATEVFEVTPSL 1618 YK LKL+G++ AI EV ++ S+ Sbjct: 401 LIIGYKELLKLKGDDTTDLDNAAIEVEVDQILSSI 435
>O15865:CDPK2_PLAFK Calcium-dependent protein kinase 2 - Plasmodium falciparum (isolate| K1 / Thailand) Length = 513 Score = 171 bits (433), Expect = 1e-41 Identities = 103/262 (39%), Positives = 146/262 (55%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y + LG+GT+ V + T + AIK KD++ K I + +EI MK + HPN Sbjct: 72 YIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRL---KNINRFFQEIEIMKKLDHPN 128 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++YE + IY++MEL +G ELFD I G E +A +Q+ +A+ Y HS + Sbjct: 129 IVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNI 188 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPEN L + + LK+ DFG LS+ + T GTP YVAP+V++ K Sbjct: 189 VHRDLKPENFLFQSENKDSLLKIIDFG---LSKNLGTGEFTTTKAGTPYYVAPQVLDGK- 244 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSC--PSW--FSTSAKKLI 1153 YD K D+WS GVI++ L+ GY PF + KK+ K +F W S+ AK LI Sbjct: 245 YD-KKCDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDAKNLI 303 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NPN R TI E +N+ W Sbjct: 304 TKLLTYNPNERCTIEEALNHPW 325
>Q8ICR0:CDPK2_PLAF7 Calcium-dependent protein kinase 2 - Plasmodium falciparum (isolate| 3D7) Length = 509 Score = 171 bits (433), Expect = 1e-41 Identities = 103/262 (39%), Positives = 146/262 (55%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y + LG+GT+ V + T + AIK KD++ K I + +EI MK + HPN Sbjct: 72 YIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRL---KNINRFFQEIEIMKKLDHPN 128 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++++YE + IY++MEL +G ELFD I G E +A +Q+ +A+ Y HS + Sbjct: 129 IVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNI 188 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPEN L + + LK+ DFG LS+ + T GTP YVAP+V++ K Sbjct: 189 VHRDLKPENFLFQSENKDSLLKIIDFG---LSKNLGTGEFTTTKAGTPYYVAPQVLDGK- 244 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSC--PSW--FSTSAKKLI 1153 YD K D+WS GVI++ L+ GY PF + KK+ K +F W S+ AK LI Sbjct: 245 YD-KKCDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDAKNLI 303 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 K+L NPN R TI E +N+ W Sbjct: 304 TKLLTYNPNERCTIEEALNHPW 325
>P62343:CDPK1_PLAFK Calcium-dependent protein kinase 1 - Plasmodium falciparum (isolate| K1 / Thailand) Length = 524 Score = 171 bits (433), Expect = 1e-41 Identities = 100/273 (36%), Positives = 149/273 (54%), Gaps = 19/273 (6%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLK------------HKMIAQIKREIST 610 R LG G + +V R AIK++ K + K K+ +I EIS Sbjct: 60 RKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNEISL 119 Query: 611 MKLIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAV 790 +K + HPN+I++++V + Y+V E GGELF++I +R + E DA +Q+++ + Sbjct: 120 LKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGI 179 Query: 791 DYCHSRGVYHRDLKPENLLLDANGTL---KVSDFGLSALSQQVREDGLLHTTCGTPNYVA 961 Y H + HRD+KPEN+LL+ +L K+ DFGLS+ +D L GT Y+A Sbjct: 180 CYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSF---FSKDNKLRDRLGTAYYIA 236 Query: 962 PEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKI----YKADFSCPSWF 1129 PEV+ K + K D+WSCGVIL++L+ GY PF N + KK+ Y DF+ Sbjct: 237 PEVLRKKYNE--KCDVWSCGVILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNI 294 Query: 1130 STSAKKLIKKILDPNPNTRITIAEVINNEWFKK 1228 S AK+LIK +L + N RIT E +N++W KK Sbjct: 295 SEEAKELIKLMLTYDYNKRITAKEALNSKWIKK 327
>P62344:CDPK1_PLAF7 Calcium-dependent protein kinase 1 - Plasmodium falciparum (isolate| 3D7) Length = 524 Score = 171 bits (433), Expect = 1e-41 Identities = 100/273 (36%), Positives = 149/273 (54%), Gaps = 19/273 (6%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLK------------HKMIAQIKREIST 610 R LG G + +V R AIK++ K + K K+ +I EIS Sbjct: 60 RKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNEISL 119 Query: 611 MKLIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAV 790 +K + HPN+I++++V + Y+V E GGELF++I +R + E DA +Q+++ + Sbjct: 120 LKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGI 179 Query: 791 DYCHSRGVYHRDLKPENLLLDANGTL---KVSDFGLSALSQQVREDGLLHTTCGTPNYVA 961 Y H + HRD+KPEN+LL+ +L K+ DFGLS+ +D L GT Y+A Sbjct: 180 CYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSF---FSKDNKLRDRLGTAYYIA 236 Query: 962 PEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKI----YKADFSCPSWF 1129 PEV+ K + K D+WSCGVIL++L+ GY PF N + KK+ Y DF+ Sbjct: 237 PEVLRKKYNE--KCDVWSCGVILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNI 294 Query: 1130 STSAKKLIKKILDPNPNTRITIAEVINNEWFKK 1228 S AK+LIK +L + N RIT E +N++W KK Sbjct: 295 SEEAKELIKLMLTYDYNKRITAKEALNSKWIKK 327
>Q9VKN7:AURKB_DROME Serine/threonine-protein kinase Ial - Drosophila melanogaster (Fruit| fly) Length = 329 Score = 171 bits (433), Expect = 1e-41 Identities = 91/261 (34%), Positives = 147/261 (56%), Gaps = 2/261 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +E+G LG G F +V AR + VA+K++ K+++ K + Q+ REI ++HP+ Sbjct: 53 FEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHPH 112 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKI--ASRGRLKEDDARKYFQQLINAVDYCHSR 808 ++R+ ++IY+ +E+ + GELF + A R E + KY Q+ NA++YCH Sbjct: 113 ILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLN 172 Query: 809 GVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGY 988 V HRDLKPEN+LL + LK++DFG SA + + T CGT +Y+ PE+++ Y Sbjct: 173 NVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKR----RTLCGTLDYLPPEMVDGNSY 228 Query: 989 DGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILD 1168 D + D W G++ + + G PFE ++ + Y KI + + S PS S K+LI +L Sbjct: 229 DDS-VDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCKELIGGLLR 287 Query: 1169 PNPNTRITIAEVINNEWFKKG 1231 RIT+ +V+ + W K G Sbjct: 288 KESKGRITLVDVMTHYWVKAG 308
>Q07832:PLK1_MOUSE Serine/threonine-protein kinase PLK1 - Mus musculus (Mouse)| Length = 603 Score = 171 bits (432), Expect = 1e-41 Identities = 102/286 (35%), Positives = 153/286 (53%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G FAK + +T E A KI+ K +LK ++ EIS + + H + Sbjct: 53 YVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQH 112 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+ ++ +++V+EL L + R L E +AR Y +Q++ Y H V Sbjct: 113 VVGFHDFFEDSDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNQV 172 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK NL L+ + +K+ DFGL+ + E T CGTPNY+APEV++ KG+ Sbjct: 173 IHRDLKLGNLFLNEDLEVKIGDFGLATKVEY--EGERKKTLCGTPNYIAPEVLSKKGH-S 229 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + D+WS G I++ L+ G PFE S L Y +I K ++S P + A LI+K+L + Sbjct: 230 FEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTD 289 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGDPA 1312 P R TI E++N+E+F GY P R + + SI S DP+ Sbjct: 290 PTARPTIHELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPS 335
>Q0VD22:STK33_BOVIN Serine/threonine-protein kinase 33 - Bos taurus (Bovine)| Length = 486 Score = 170 bits (430), Expect = 2e-41 Identities = 99/268 (36%), Positives = 159/268 (59%), Gaps = 13/268 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G+F V A + E AIK ++K+K + ++RE+ +K ++H + Sbjct: 116 YTFGRILGQGSFGMVIEAIDKERETKWAIKKVNKEKA-GSSAVKLLEREVDILKSVKHEH 174 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I + +V + K+Y+VMEL GEL + + +G E++ R Q L +A+ Y H++ + Sbjct: 175 IIHLEQVFETPKKMYLVMELCEDGELKEILERKGHFSENETRWIIQSLASAIAYLHNKDI 234 Query: 815 YHRDLKPENLL-----LDANG----TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPE 967 HRDLK EN++ +DAN +KV+DFGL A+ + R + +L TTCGTP Y+APE Sbjct: 235 VHRDLKLENIMVKSSFIDANNEMNLNIKVTDFGL-AVKKHGRSEVMLQTTCGTPIYMAPE 293 Query: 968 VINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKAD--FSCPSWFSTS- 1138 VIN Y + D+WS GVI+++L+ G PF S+ L++ I K + F W S S Sbjct: 294 VINAHDY-SQQCDIWSIGVIMYILLCGKAPFMASSEEKLFELIKKGELHFKNSIWNSISD 352 Query: 1139 -AKKLIKKILDPNPNTRITIAEVINNEW 1219 AK ++K+++ +P RIT E+++N+W Sbjct: 353 CAKSVLKQLMKVDPAHRITAKELLDNQW 380
>Q9N2L7:PLK2_CAEEL Serine/threonine-protein kinase plk-2 - Caenorhabditis elegans| Length = 632 Score = 170 bits (430), Expect = 2e-41 Identities = 92/264 (34%), Positives = 146/264 (55%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE G+ LG+G FA RN TGE A K++ K ++K ++ +E+ + ++H N Sbjct: 36 YEKGKFLGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQHRN 95 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+++Y ++ +YI +EL L + R + E +AR + Q++ V Y H+ + Sbjct: 96 VVKLYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTYQIVEGVLYLHNLKI 155 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK NL L+ +K+ DFGL+ D T CGTPNY+APEV+N G+ Sbjct: 156 VHRDLKLGNLFLNDELQVKIGDFGLATTCD---NDERKKTLCGTPNYIAPEVLNKIGH-S 211 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 + DLW+ G IL++L+ G+ PFE +L Y +I ++ P+ S +A +LI+ +LDP Sbjct: 212 FEVDLWAIGCILYILLFGHPPFESKSLEETYSRIKNNNYVIPTSASAAASQLIRVLLDPV 271 Query: 1175 PNTRITIAEVINNEWFKKGYQPPR 1246 P+ R V + +FK G+ P R Sbjct: 272 PSRRPNARAVCRDHFFKSGFMPAR 295
>Q9WTK7:STK11_MOUSE Serine/threonine-protein kinase 11 - Mus musculus (Mouse)| Length = 436 Score = 169 bits (429), Expect = 3e-41 Identities = 95/264 (35%), Positives = 151/264 (57%), Gaps = 6/264 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLK-HKMIAQIKREISTMKLIRHP 631 Y +G LGEG++ KVK + ET A+KIL K K+ + A +K+EI ++ +RH Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHR 108 Query: 632 NVIRMYEVMAS--RTKIYIVMELVTGG--ELFDKIASRGRLKEDDARKYFQQLINAVDYC 799 NVI++ +V+ + + K+Y+VME G E+ D + + R A YF+QLI+ ++Y Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK-RFPVCQAHGYFRQLIDGLEYL 167 Query: 800 HSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINN 979 HS+G+ H+D+KP NLLL NGTLK+SD G++ D T+ G+P + PE+ N Sbjct: 168 HSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQPPEIANG 227 Query: 980 -KGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIK 1156 + G K D+WS GV L+ + G PFE N+ L++ I + DF+ P L++ Sbjct: 228 LDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGRGDFTIPCDCGPPLSDLLR 287 Query: 1157 KILDPNPNTRITIAEVINNEWFKK 1228 +L+ P R +I ++ + WF+K Sbjct: 288 GMLEYEPAKRFSIRQIRQHSWFRK 311
>Q9R011:PLK3_RAT Serine/threonine-protein kinase PLK3 - Rattus norvegicus (Rat)| Length = 615 Score = 169 bits (429), Expect = 3e-41 Identities = 93/264 (35%), Positives = 149/264 (56%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G FA+ A + ET A+K++ + +V K +I EI + ++H + Sbjct: 31 YIKGRLLGKGGFARCYEATDTETSIAYAVKVIPQSRVAKPHQREKIINEIELHRDLQHRH 90 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R IYI +EL + L +R L E + R Y +Q+++ + Y H RG+ Sbjct: 91 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 150 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK N + N LKV DFGL+A + + T CGTPNYVAPEV+ +G+ G Sbjct: 151 LHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQ--RKKTICGTPNYVAPEVLLRQGH-G 207 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 +AD+WS G +++ L+ G PFE ++L Y+ I + ++ P+ S A++L+ IL + Sbjct: 208 PEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRAS 267 Query: 1175 PNTRITIAEVINNEWFKKGYQPPR 1246 P R +I +++ +++F KGY P R Sbjct: 268 PRDRPSIEQILRHDFFTKGYTPDR 291
>O43293:DAPK3_HUMAN Death-associated protein kinase 3 - Homo sapiens (Human)| Length = 454 Score = 169 bits (429), Expect = 3e-41 Identities = 93/268 (34%), Positives = 157/268 (58%), Gaps = 11/268 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIA---QIKREISTMKLIR 625 YE+G LG G FA V+ R TG+ A K + K ++ + +I+RE++ ++ IR Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR 72 Query: 626 HPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHS 805 HPN+I ++++ ++T + +++ELV+GGELFD +A + L ED+A ++ +Q+++ V Y HS Sbjct: 73 HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132 Query: 806 RGVYHRDLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI 973 + + H DLKPEN++L N +K+ DFG ++ ++ GTP +VAPE++ Sbjct: 133 KRIAHFDLKPENIMLLDKNVPNPRIKLIDFG---IAHKIEAGNEFKNIFGTPEFVAPEIV 189 Query: 974 NNKGYDGAKADLWSCGVILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSWFSTSA 1141 N + G +AD+WS GVI ++L++G PF + L + Y D S S A Sbjct: 190 NYEPL-GLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELA 248 Query: 1142 KKLIKKILDPNPNTRITIAEVINNEWFK 1225 K I+++L +P R+TIA+ + + W K Sbjct: 249 KDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>O96017:CHK2_HUMAN Serine/threonine-protein kinase Chk2 - Homo sapiens (Human)| Length = 543 Score = 169 bits (428), Expect = 4e-41 Identities = 111/312 (35%), Positives = 162/312 (51%), Gaps = 16/312 (5%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVL-----KHKMIAQIKREISTMKL 619 Y + +TLG G +VK A +T + VAIKI+ K K + ++ EI +K Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279 Query: 620 IRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYC 799 + HP +I++ + YIV+EL+ GGELFDK+ RLKE + YF Q++ AV Y Sbjct: 280 LNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYL 338 Query: 800 HSRGVYHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEV 970 H G+ HRDLKPEN+LL + + +K++DFG S + + E L+ T CGTP Y+APEV Sbjct: 339 HENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKI---LGETSLMRTLCGTPTYLAPEV 395 Query: 971 ---INNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY---KADFSCPSWFS 1132 + GY+ A D WS GVILF+ ++GY PF + K K +F W Sbjct: 396 LVSVGTAGYNRA-VDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAE 454 Query: 1133 TSAK--KLIKKILDPNPNTRITIAEVINNEWFKKGYQPPRFETAEVNLDDINSIFNESGD 1306 S K L+KK+L +P R T E + + W + +F+ D+ S NES Sbjct: 455 VSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQ-------DLLSEENESTA 507 Query: 1307 PAQLVVERREER 1342 Q++ + R Sbjct: 508 LPQVLAQPSTSR 519
>P70032:PLK1_XENLA Serine/threonine-protein kinase PLK1 - Xenopus laevis (African clawed| frog) Length = 598 Score = 169 bits (427), Expect = 5e-41 Identities = 100/268 (37%), Positives = 148/268 (55%), Gaps = 1/268 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G FAK ++E+ E A KI+ K +LK ++ EI+ + + H + Sbjct: 44 YLRGRFLGKGGFAKCYEITDLESREVFAGKIVPKTMLLKPHQKDKMTMEIAIQRSLDHRH 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+ + +Y+V+EL L + R + E +AR Y +Q I+ Y HS V Sbjct: 104 VVGFHGFFEDNDFVYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTISGCQYLHSNRV 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDG-LLHTTCGTPNYVAPEVINNKGYD 991 HRDLK NL L+ +K+ DFGL+ +V DG T CGTPNY+APEV+ KG+ Sbjct: 164 IHRDLKLGNLFLNDEMEVKIGDFGLAT---KVEYDGERKKTLCGTPNYIAPEVLGKKGH- 219 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 + D+WS G I++ L+ G PFE S L Y +I K ++S P + A LI+K+L Sbjct: 220 SFEVDIWSIGCIMYTLLVGKPPFETSCLKETYMRIKKNEYSIPKHINPVAAALIQKMLRS 279 Query: 1172 NPNTRITIAEVINNEWFKKGYQPPRFET 1255 +P +R TI +++N+E+F GY P R T Sbjct: 280 DPTSRPTIDDLLNDEFFTSGYIPSRLPT 307
>O88764:DAPK3_RAT Death-associated protein kinase 3 - Rattus norvegicus (Rat)| Length = 448 Score = 169 bits (427), Expect = 5e-41 Identities = 94/268 (35%), Positives = 157/268 (58%), Gaps = 11/268 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIA---QIKREISTMKLIR 625 YE+G LG G FA V+ + TG A K + K ++ + +I+RE+S ++ IR Sbjct: 13 YEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIR 72 Query: 626 HPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHS 805 HPN+I +++V ++T + +++ELV+GGELFD +A + L ED+A ++ +Q+++ V Y HS Sbjct: 73 HPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132 Query: 806 RGVYHRDLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI 973 + + H DLKPEN++L A+ +K+ DFG ++ ++ GTP +VAPE++ Sbjct: 133 KRIAHFDLKPENIMLLDKHAASPRIKLIDFG---IAHRIEAGSEFKNIFGTPEFVAPEIV 189 Query: 974 NNKGYDGAKADLWSCGVILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSWFSTSA 1141 N + G +AD+WS GVI ++L++G PF + L + Y D S S A Sbjct: 190 NYEPL-GLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELA 248 Query: 1142 KKLIKKILDPNPNTRITIAEVINNEWFK 1225 K I+++L +P R+TIA+ + + W K Sbjct: 249 KDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>O54784:DAPK3_MOUSE Death-associated protein kinase 3 - Mus musculus (Mouse)| Length = 448 Score = 169 bits (427), Expect = 5e-41 Identities = 94/268 (35%), Positives = 157/268 (58%), Gaps = 11/268 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIA---QIKREISTMKLIR 625 YE+G LG G FA V+ + TG A K + K ++ + +I+RE+S ++ IR Sbjct: 13 YEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIR 72 Query: 626 HPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHS 805 HPN+I +++V ++T + +++ELV+GGELFD +A + L ED+A ++ +Q+++ V Y HS Sbjct: 73 HPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132 Query: 806 RGVYHRDLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI 973 + + H DLKPEN++L A+ +K+ DFG ++ ++ GTP +VAPE++ Sbjct: 133 KRIAHFDLKPENIMLLDKHAASPRIKLIDFG---IAHRIEAGSEFKNIFGTPEFVAPEIV 189 Query: 974 NNKGYDGAKADLWSCGVILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSWFSTSA 1141 N + G +AD+WS GVI ++L++G PF + L + Y D S S A Sbjct: 190 NYEPL-GLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELA 248 Query: 1142 KKLIKKILDPNPNTRITIAEVINNEWFK 1225 K I+++L +P R+TIA+ + + W K Sbjct: 249 KDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>O75582:KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 - Homo sapiens (Human)| Length = 802 Score = 168 bits (426), Expect = 6e-41 Identities = 101/272 (37%), Positives = 160/272 (58%), Gaps = 15/272 (5%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIR-HPNVIR 643 + LGEG+F+ + + ++ + A+KI+ K +M A ++EI+ +KL HPN+++ Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISK------RMEANTQKEITALKLCEGHPNIVK 483 Query: 644 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 823 ++EV + ++VMEL+ GGELF++I + E +A ++L++AV + H GV HR Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHR 543 Query: 824 DLKPENLLL-DANGTL--KVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 DLKPENLL D N L K+ DFG + L ++ L T C T +Y APE++N GYD Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFARLKPP--DNQPLKTPCFTLHYAAPELLNQNGYD- 600 Query: 995 AKADLWSCGVILFVLMAGYLPFED-------SNLMALYKKIYKADFSC--PSW--FSTSA 1141 DLWS GVIL+ +++G +PF+ ++ + + KKI K DFS +W S A Sbjct: 601 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA 660 Query: 1142 KKLIKKILDPNPNTRITIAEVINNEWFKKGYQ 1237 K LI+ +L +PN R+ ++ + NEW + G Q Sbjct: 661 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQ 692 Score = 136 bits (343), Expect = 3e-31 Identities = 80/256 (31%), Positives = 147/256 (57%), Gaps = 11/256 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNV---ETGENVAIKILDKDKVL-KHKMIAQIKREISTMKLI 622 +EL + LG G + KV R + +TG+ A+K+L K ++ K K + E ++ I Sbjct: 49 FELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHI 108 Query: 623 RH-PNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYC 799 R P ++ ++ + TK++++++ + GGELF ++ R R E + + Y +++ A+++ Sbjct: 109 RQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHL 168 Query: 800 HSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI-- 973 H G+ +RD+K EN+LLD+NG + ++DFGLS E ++ CGT Y+AP+++ Sbjct: 169 HKLGIIYRDIKLENILLDSNGHVVLTDFGLSK-EFVADETERAYSFCGTIEYMAPDIVRG 227 Query: 974 NNKGYDGAKADLWSCGVILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSWFSTSA 1141 + G+D A D WS GV+++ L+ G PF E ++ + ++I K++ P S A Sbjct: 228 GDSGHDKA-VDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALA 286 Query: 1142 KKLIKKILDPNPNTRI 1189 K LI+++L +P R+ Sbjct: 287 KDLIQRLLMKDPKKRL 302
>Q15831:STK11_HUMAN Serine/threonine-protein kinase 11 - Homo sapiens (Human)| Length = 433 Score = 168 bits (425), Expect = 8e-41 Identities = 95/268 (35%), Positives = 150/268 (55%), Gaps = 6/268 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLK-HKMIAQIKREISTMKLIRHP 631 Y +G LGEG++ KVK + ET A+KIL K K+ + A +K+EI ++ +RH Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108 Query: 632 NVIRMYEVMAS--RTKIYIVMELVTGG--ELFDKIASRGRLKEDDARKYFQQLINAVDYC 799 NVI++ +V+ + + K+Y+VME G E+ D + + R A YF QLI+ ++Y Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK-RFPVCQAHGYFCQLIDGLEYL 167 Query: 800 HSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINN 979 HS+G+ H+D+KP NLLL GTLK+SD G++ D T+ G+P + PE+ N Sbjct: 168 HSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANG 227 Query: 980 -KGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIK 1156 + G K D+WS GV L+ + G PFE N+ L++ I K ++ P L+K Sbjct: 228 LDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLK 287 Query: 1157 KILDPNPNTRITIAEVINNEWFKKGYQP 1240 +L+ P R +I ++ + WF+K + P Sbjct: 288 GMLEYEPAKRFSIRQIRQHSWFRKKHPP 315
>Q21734:KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-1 - Caenorhabditis elegans| Length = 784 Score = 168 bits (425), Expect = 8e-41 Identities = 88/248 (35%), Positives = 150/248 (60%), Gaps = 3/248 (1%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNV---ETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIR 625 +EL + LG+G+F KV R V ++G A+K+L K LK + + K E + + I Sbjct: 104 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKK-ATLKVRDRQRTKLERNILAHIS 162 Query: 626 HPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHS 805 HP +++++ + K+Y++++ + GG+LF +++ EDD + Y +L A+++ HS Sbjct: 163 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 222 Query: 806 RGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 G+ +RDLKPEN+LLDA+G +KV+DFGLS + + + ++ CGT Y+APEVIN +G Sbjct: 223 LGIVYRDLKPENILLDADGHIKVTDFGLS--KEAIDSEKKTYSFCGTVEYMAPEVINRRG 280 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 1165 + A AD WS GV++F ++ G+LPF+ + +I KA S P + + A+ L++ + Sbjct: 281 HSMA-ADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALF 339 Query: 1166 DPNPNTRI 1189 N R+ Sbjct: 340 KRNSQNRL 347 Score = 131 bits (329), Expect = 1e-29 Identities = 88/270 (32%), Positives = 137/270 (50%), Gaps = 15/270 (5%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 YE+ +G G + V + T A+KI+ K + E+ L+RH + Sbjct: 454 YEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKK-------AVFDATEEVDI--LLRHSH 504 Query: 635 ---VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRL-KEDDARKYFQQLINAVDYCH 802 V+++++V T IY++ EL GGEL DK+ ++ L E + L+NAV Y H Sbjct: 505 HQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLH 564 Query: 803 SRGVYHRDLKPENLLLDAN----GTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEV 970 S+ V HRDL N+L +L++ DFG + Q E+G+L T C T +VAPEV Sbjct: 565 SQQVAHRDLTAANILFALKDGDPSSLRIVDFGFA--KQSRAENGMLMTPCYTAQFVAPEV 622 Query: 971 INNKGYDGAKADLWSCGVILFVLMAGYLPF----EDSNLMALYK-KIYKADFSCPSW--F 1129 + +GYD D+WS GV+L ++ G PF D+ L + K + P W Sbjct: 623 LRKQGYD-RSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTI 681 Query: 1130 STSAKKLIKKILDPNPNTRITIAEVINNEW 1219 S AK L++K+LD +PN R+T + + ++W Sbjct: 682 SDEAKDLVRKMLDVDPNRRVTAKQALQHKW 711
>Q7RAH3:CDPK1_PLAYO Calcium-dependent protein kinase 1 - Plasmodium yoelii yoelii| Length = 535 Score = 168 bits (425), Expect = 8e-41 Identities = 97/271 (35%), Positives = 146/271 (53%), Gaps = 17/271 (6%) Frame = +2 Query: 467 RTLGEGTFAKVKFARNVETGENVAIKILDKDKVLK----------HKMIAQIKREISTMK 616 R LG G + +V + AIK++ K + K K +I EIS +K Sbjct: 61 RKLGSGAYGEVLLCKEKNGHSEKAIKVIKKSQFDKGRYNDDNKNIEKFHEEIYNEISLLK 120 Query: 617 LIRHPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDY 796 + HPN+I++++V + Y+V E GGELF++I +R + E DA +Q+++ + Y Sbjct: 121 SLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICY 180 Query: 797 CHSRGVYHRDLKPENLLLDANGTL---KVSDFGLSALSQQVREDGLLHTTCGTPNYVAPE 967 H + HRD+KPEN+LL+ +L K+ DFGLS+ +D L GT Y+APE Sbjct: 181 LHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSF---FSKDYKLRDRLGTAYYIAPE 237 Query: 968 VINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKI----YKADFSCPSWFST 1135 V+ K + K D+WSCGVI+++L+ GY PF N + KK+ Y DF+ S Sbjct: 238 VLKKKYNE--KCDVWSCGVIMYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISD 295 Query: 1136 SAKKLIKKILDPNPNTRITIAEVINNEWFKK 1228 AK+LIK +L + N R T E +N+ W KK Sbjct: 296 EAKELIKLMLTYDYNKRCTAEEALNSRWIKK 326
>P53682:CDPK1_ORYSJ Calcium-dependent protein kinase, isoform 1 - Oryza sativa subsp.| japonica (Rice) Length = 534 Score = 168 bits (425), Expect = 8e-41 Identities = 102/263 (38%), Positives = 142/263 (53%), Gaps = 8/263 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMK-LIRHP 631 Y LGR LG+G F K + TG A K + K + I ++REI M L Sbjct: 73 YTLGRELGQGQFGKTYLCTEISTGCQYACKTILKSNLRCVSDIEDVRREIQIMHHLSGQK 132 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 N++ + + ++IVMEL GGELF KI RG E A + + ++ ++ CHS G Sbjct: 133 NIVTIKDTYEDEQAVHIVMELCAGGELFSKIQKRGHYSERKAAELIKIIVGIIETCHSHG 192 Query: 812 VYHRDLKPEN-LLLDANG--TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 V HRDLKPEN LLLDA+ ++K DFGLS R + G+P Y+APEV+ + Sbjct: 193 VMHRDLKPENFLLLDADDEFSVKAIDFGLSVF---FRPGQVFREVVGSPYYIAPEVLEKR 249 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKL 1150 G +AD+W+ GVIL+VL+ G PF +Y+K+ + DF W S SAK L Sbjct: 250 --YGPEADIWTAGVILYVLLTGVPPFWADTQSGIYEKVLDGRIDFKSNRWPRISDSAKDL 307 Query: 1151 IKKILDPNPNTRITIAEVINNEW 1219 IKK+L P P+ R+ EV+ + W Sbjct: 308 IKKMLCPYPSERLKAHEVLKHPW 330
>Q06850:CDPK1_ARATH Calcium-dependent protein kinase, isoform AK1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 610 Score = 168 bits (425), Expect = 8e-41 Identities = 119/360 (33%), Positives = 181/360 (50%), Gaps = 13/360 (3%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMK-LIRHP 631 Y LGR LG+G F TG+ A K + K K+L + + ++REI M L HP Sbjct: 150 YSLGRKLGQGQFGTTFLCVEKTTGKEFACKSIAKRKLLTDEDVEDVRREIQIMHHLAGHP 209 Query: 632 NVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 811 NVI + +++VME GGELFD+I RG E A + + ++ V+ CHS G Sbjct: 210 NVISIKGAYEDVVAVHLVMECCAGGELFDRIIQRGHYTERKAAELTRTIVGVVEACHSLG 269 Query: 812 VYHRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNK 982 V HRDLKPEN L + LK DFGLS + D + G+P YVAPEV+ + Sbjct: 270 VMHRDLKPENFLFVSKHEDSLLKTIDFGLSMF---FKPDDVFTDVVGSPYYVAPEVLRKR 326 Query: 983 GYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKL 1150 G +AD+WS GVI+++L++G PF +++++ DFS W S SAK L Sbjct: 327 --YGPEADVWSAGVIVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAKDL 384 Query: 1151 IKKILDPNPNTRITIAEVINNEWFK-KGYQPPR-FETAEVNLDDINSIFNESGDPAQLVV 1324 ++K+L +P R+T +V+ + W + G P + ++A ++ S N+ A V+ Sbjct: 385 VRKMLVRDPKKRLTAHQVLCHPWVQVDGVAPDKPLDSAVLSRMKQFSAMNKFKKMALRVI 444 Query: 1325 ER---REERPAVMNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAA 1495 EE + F +I + + FE+ +K R + L +EIL ++AA Sbjct: 445 AESLSEEEIAGLKEMFNMIDADKSGQI--TFEELKAGLK---RVGANLKESEILDLMQAA 499
>P34208:CHK1_SCHPO Serine/threonine-protein kinase chk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 496 Score = 167 bits (423), Expect = 1e-40 Identities = 131/478 (27%), Positives = 211/478 (44%), Gaps = 64/478 (13%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIA----QIKREISTMKLI 622 Y +GR +G G FA V+ + + + A+K ++K ++ EI KL Sbjct: 10 YHIGREIGTGAFASVRLCYD-DNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLC 68 Query: 623 R-HPNVIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYC 799 H N+I Y + ++V+E GG+LFDKI + ED A+ YF QL+ + + Sbjct: 69 NGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFM 128 Query: 800 HSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINN 979 HS+GV HRDLKPEN+LLD NG LK+SDFG ++L + LL++ G+P Y APE+ Sbjct: 129 HSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEI--T 186 Query: 980 KGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSW-----FSTSAK 1144 + YDG+K D+WSCG+ILF L+ G P++++ +YK PS+ S A Sbjct: 187 QQYDGSKVDVWSCGIILFALLLGNTPWDEAISNTGDYLLYKKQCERPSYHPWNLLSPGAY 246 Query: 1145 KLIKKILDPNPNTRITIAEVINNEWF--------KKG-------------------YQPP 1243 +I +L +P R ++ V+ + W K G P Sbjct: 247 SIITGMLRSDPFKRYSVKHVVQHPWLTSSTPFRTKNGNCADPVALASRLMLKLRIDLDKP 306 Query: 1244 RFETAEVNLDDIN-------------------SIFNESGDPAQL-----VVERREERPAV 1351 R ++ + +D ++ P QL V E E+ P++ Sbjct: 307 RLASSRASQNDSGFSMTQPAFKKNDQKELDRVEVYGALSQPVQLNKNIDVTEILEKDPSL 366 Query: 1352 MNAFELISTSQGLNLGTLFEKQTDSVKRETRFASRLPANEILSKIEAAAGPMGFNVQK-- 1525 E + L + +R TRF SR I+ + + + +V Sbjct: 367 SQFCENEGFIKRLAKKAKNFYEICPPERLTRFYSRASRETIIDHLYDSLRLLAISVTMKY 426 Query: 1526 -RNYKLKLQGENPGRKGQLAIATEVFEVTPSLYMVELRKSNGDTLEFHKFYHSISNGL 1696 RN + + RK L E+ + +L ++ K NGD LE+ KF+ ++ + + Sbjct: 427 VRNQTILYVNLHDKRKCLLQGVIELTNLGHNLELINFIKRNGDPLEWRKFFKNVVSSI 484
>Q9BYT3:STK33_HUMAN Serine/threonine-protein kinase 33 - Homo sapiens (Human)| Length = 514 Score = 167 bits (422), Expect = 2e-40 Identities = 96/268 (35%), Positives = 159/268 (59%), Gaps = 13/268 (4%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G+F V A + ET AIK ++K+K + ++RE++ +K ++H + Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKHEH 174 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 +I + +V + K+Y+VMEL GEL + + +G E++ R Q L +A+ Y H+ + Sbjct: 175 IIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDI 234 Query: 815 YHRDLKPENLLL---------DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPE 967 HRDLK EN+++ + N +KV+DFGL A+ +Q R + +L TCGTP Y+APE Sbjct: 235 VHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGL-AVKKQSRSEAMLQATCGTPIYMAPE 293 Query: 968 VINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKAD--FSCPSWFSTS- 1138 VI+ Y + D+WS GV++++L+ G PF S+ L++ I K + F W S S Sbjct: 294 VISAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISD 352 Query: 1139 -AKKLIKKILDPNPNTRITIAEVINNEW 1219 AK ++K+++ +P RIT E+++N+W Sbjct: 353 CAKSVLKQLMKVDPAHRITAKELLDNQW 380
>P53351:PLK2_MOUSE Serine/threonine-protein kinase PLK2 - Mus musculus (Mouse)| Length = 682 Score = 167 bits (422), Expect = 2e-40 Identities = 86/268 (32%), Positives = 152/268 (56%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y G+ LG+G FAK ++ + A KI+ +V K +I +EI +L+ H + Sbjct: 79 YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKH 138 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V++ Y + IYI++E + + + +R L E + R Y +Q+++ + Y H + + Sbjct: 139 VVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEI 198 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 994 HRDLK N ++ LKV DFGL+A + + + T CGTPNY++PEV+N +G+ G Sbjct: 199 LHRDLKLGNFFINEAMELKVGDFGLAARLEPL--EHRRRTICGTPNYLSPEVLNKQGH-G 255 Query: 995 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 1174 ++D+W+ G +++ ++ G PFE +NL Y+ I +A ++ PS AK LI +L N Sbjct: 256 CESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKN 315 Query: 1175 PNTRITIAEVINNEWFKKGYQPPRFETA 1258 P R ++ ++I +++F +G+ P R ++ Sbjct: 316 PEDRPSLDDIIRHDFFLQGFTPDRLSSS 343
>P62205:PLK1_XENTR Serine/threonine-protein kinase PLK1 - Xenopus tropicalis (Western| clawed frog) (Silurana tropicalis) Length = 598 Score = 167 bits (422), Expect = 2e-40 Identities = 100/268 (37%), Positives = 146/268 (54%), Gaps = 1/268 (0%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y GR LG+G FAK ++E+ E A KI+ K +LK ++ EI+ + + H + Sbjct: 44 YLRGRFLGKGGFAKCYEITDLESREVFAGKIVPKTMLLKPHQKDKMTMEIAIQRSLDHRH 103 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 V+ + +Y+V+EL L + R + E +AR Y +Q I Y HS V Sbjct: 104 VVGFHGFFEDNDFVYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTILGCQYLHSNRV 163 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDG-LLHTTCGTPNYVAPEVINNKGYD 991 HRDLK NL L+ +K+ DFGL+ +V DG T CGTPNY+APEV+ KG+ Sbjct: 164 IHRDLKLGNLFLNDEMEVKIGDFGLAT---KVEYDGERKKTLCGTPNYIAPEVLGKKGH- 219 Query: 992 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDP 1171 + D+WS G I++ L+ G PFE S L Y +I K ++S P + A LI+K+L Sbjct: 220 SFEVDIWSIGCIMYTLLVGKPPFETSCLKETYMRIKKNEYSVPKHINPMATALIQKMLRS 279 Query: 1172 NPNTRITIAEVINNEWFKKGYQPPRFET 1255 P +R TI +++N+E+F GY P R T Sbjct: 280 EPTSRPTIDDLLNDEFFTTGYIPSRLPT 307
>P54644:KRAC_DICDI RAC-family serine/threonine-protein kinase homolog - Dictyostelium| discoideum (Slime mold) Length = 444 Score = 166 bits (421), Expect = 2e-40 Identities = 95/299 (31%), Positives = 160/299 (53%), Gaps = 18/299 (6%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 +EL +G+G+F KV R +TGE A+K+L K +++H + E + ++ I HP Sbjct: 120 FELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKINHPF 179 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++ + + K+Y +++ V GGELF + + ED R Y +++ A+++ H GV Sbjct: 180 LVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGV 239 Query: 815 YHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTT------CGTPNYVAPEVIN 976 +RDLKPENLLL G + ++DFGL ++GLL T CGTP Y+APEV+ Sbjct: 240 IYRDLKPENLLLTNEGHICMTDFGLC-------KEGLLTPTDKTGTFCGTPEYLAPEVLQ 292 Query: 977 NKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIK 1156 GY G + D WS G +L+ ++ G PF + ++ +Y+KI S P + S A+ L++ Sbjct: 293 GNGY-GKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLE 351 Query: 1157 KILDPNPNTRITIAEVINN-------EW---FKKGYQPPRFETAEVNLD--DINSIFNE 1297 ++L+ +P R+ +I +W F+K PP + + D I+ +F + Sbjct: 352 QLLERDPEKRLADPNLIKRHPFFRSIDWEQLFQKNIPPPFIPNVKGSADTSQIDPVFTD 410
>P11730:KCC2G_RAT Calcium/calmodulin-dependent protein kinase type II gamma chain -| Rattus norvegicus (Rat) Length = 527 Score = 166 bits (421), Expect = 2e-40 Identities = 95/262 (36%), Positives = 149/262 (56%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + + A KI++ K L + +++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA Q++ +V++ H + Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDI 132 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ Q E GTP Y++PEV+ Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GEQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 ++L NP RIT + + + W Sbjct: 250 NQMLTINPAKRITADQALKHPW 271
>Q923T9:KCC2G_MOUSE Calcium/calmodulin-dependent protein kinase type II gamma chain - Mus| musculus (Mouse) Length = 529 Score = 166 bits (421), Expect = 2e-40 Identities = 95/262 (36%), Positives = 149/262 (56%), Gaps = 7/262 (2%) Frame = +2 Query: 455 YELGRTLGEGTFAKVKFARNVETGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 634 Y+L LG+G F+ V+ + + A KI++ K L + +++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 635 VIRMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV 814 ++R+++ ++ Y+V +LVTGGELF+ I +R E DA Q++ +V++ H + Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDI 132 Query: 815 YHRDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 985 HRDLKPENLLL + +K++DFGL+ Q E GTP Y++PEV+ Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GEQQAWFGFAGTPGYLSPEVLRKDP 190 Query: 986 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLI 1153 Y G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 1154 KKILDPNPNTRITIAEVINNEW 1219 ++L NP RIT + + + W Sbjct: 250 NQMLTINPAKRITADQALKHPW 271 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 301,138,541 Number of extensions: 6272246 Number of successful extensions: 25323 Number of sequences better than 10.0: 2614 Number of HSP's gapped: 20482 Number of HSP's successfully gapped: 2750 Length of query: 644 Length of database: 100,686,439 Length adjustment: 120 Effective length of query: 524 Effective length of database: 67,771,039 Effective search space: 35512024436 Effective search space used: 35512024436 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
