ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf55h20 |
|---|---|
| Clone Library Name | barley_pub |
>P93438:METL_ORYSJ S-adenosylmethionine synthetase 2 - Oryza sativa subsp. japonica| (Rice) Length = 394 Score = 497 bits (1280), Expect = e-140 Identities = 269/394 (68%), Positives = 288/394 (73%), Gaps = 58/394 (14%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQD DSKVACET TKTNMVMV GEIT Sbjct: 1 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDPDSKVACETCTKTNMVMVFGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPD---------------I 403 TKATVDYEKIVRDTCR IGF+SDDVGLDADRCKVLVNIEQQSPD I Sbjct: 61 TKATVDYEKIVRDTCRGIGFVSDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEI 120 Query: 404 AQGVHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYAT 487 G GH + PE ++GA G + Y Sbjct: 121 GAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYLN 180 Query: 488 DETPELMPLSH-----------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRF 634 D + H V ++ A LKEHVIKPVIP KYLDE TIFHLNPSGRF Sbjct: 181 DAGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPDKYLDEKTIFHLNPSGRF 240 Query: 635 VIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGL 814 VIGGPHGDAGLTGRKIIIDTY KDPTKVDRSGAYIARQAAKSI+ASGL Sbjct: 241 VIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIARQAAKSIVASGL 300 Query: 815 ARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGG 994 ARRCIVQ+SYAIGVPEPLSVFVDSYGTGKIPD+EILK+VKENFDFRPGM++INLDLK+GG Sbjct: 301 ARRCIVQVSYAIGVPEPLSVFVDSYGTGKIPDKEILKIVKENFDFRPGMMTINLDLKRGG 360 Query: 995 NRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 NRFIKTAAYGHFGR+D DFTWEVVKPLK++KAS+ Sbjct: 361 NRFIKTAAYGHFGREDPDFTWEVVKPLKYEKASS 394
>P43280:METK_SOLLC S-adenosylmethionine synthetase 1 - Solanum lycopersicum (Tomato)| (Lycopersicon esculentum) Length = 393 Score = 479 bits (1233), Expect = e-134 Identities = 260/389 (66%), Positives = 281/389 (72%), Gaps = 59/389 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQ+SDAVLDACL QD +SKVACET TKTN+VMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPESKVACETCTKTNLVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQ---------------G 412 VDYEKIVRDTCRNIGF+SDDVGLDAD CKVLV IEQQSPDIAQ G Sbjct: 62 IVDYEKIVRDTCRNIGFVSDDVGLDADNCKVLVYIEQQSPDIAQGVHGHLTKRPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y+ D Sbjct: 122 DQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYSNDNG 181 Query: 497 PELMPLSH-----------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 + H V ++ LKEHVIKPVIP KYLDENTIFHLNPSGRFVIG Sbjct: 182 AMVPIRVHTVLISTQHDETVTNDEIARDLKEHVIKPVIPEKYLDENTIFHLNPSGRFVIG 241 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKSI+ASGLARR Sbjct: 242 GPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASGLARR 301 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN-R 1000 CIVQ+SYAIGVPEPLSVFVD+YGTGKIPDREILK+VKENFDFRPGM+SINLDLK+GGN R Sbjct: 302 CIVQVSYAIGVPEPLSVFVDTYGTGKIPDREILKIVKENFDFRPGMMSINLDLKRGGNRR 361 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDK 1087 F+KTAAYGHFGRDD DFTWEVVKPLK++K Sbjct: 362 FLKTAAYGHFGRDDPDFTWEVVKPLKWEK 390
>Q96552:METL_CATRO S-adenosylmethionine synthetase 2 - Catharanthus roseus (Rosy| periwinkle) (Madagascar periwinkle) Length = 393 Score = 477 bits (1228), Expect = e-134 Identities = 259/392 (66%), Positives = 280/392 (71%), Gaps = 59/392 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQ+SDAVLDACLAQD +SKVACET TKTNMVMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQISDAVLDACLAQDPESKVACETCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPD---------------IAQG 412 VDYEKIVRDTCR IGF+SDDVGLDAD CKVLVNIEQQSPD I G Sbjct: 62 QVDYEKIVRDTCRAIGFVSDDVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKRPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y D Sbjct: 122 DQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYYNDNG 181 Query: 497 PELMPLSH-----------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 + H V ++ A LKEHVIKPV+P KYLDE TIFHLNPSGRFVIG Sbjct: 182 AMVPIRVHTVLISTQHDETVTNDEIAADLKEHVIKPVVPEKYLDEKTIFHLNPSGRFVIG 241 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKSI+ASGLARR Sbjct: 242 GPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASGLARR 301 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN-R 1000 CIVQ+SYAIGVPEPLSVFVD+YGTGKIPD+EILK+VKENFDFRPGMI+INLDLK+GGN R Sbjct: 302 CIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKENFDFRPGMIAINLDLKRGGNSR 361 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 F+KTAAYGHFGR+D DFTWEVVKPLKF+K A Sbjct: 362 FLKTAAYGHFGREDPDFTWEVVKPLKFEKVEA 393
>Q96551:METK_CATRO S-adenosylmethionine synthetase 1 - Catharanthus roseus (Rosy| periwinkle) (Madagascar periwinkle) Length = 393 Score = 477 bits (1228), Expect = e-134 Identities = 260/392 (66%), Positives = 289/392 (73%), Gaps = 60/392 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQ+SDAVLDACL QD DSKVACET TKTNMVMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPD---------------IAQG 412 TVDYEKIVRDTCR+IGF+SDDVGLDAD CKVLVNIEQQSPD I G Sbjct: 62 TVDYEKIVRDTCRSIGFVSDDVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKRPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y +E Sbjct: 122 DQGHMFGYATDETPEFMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYY-NEN 180 Query: 497 PELMPL---SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 ++P+ + V++T+ + A LKEHVIKPVIP KYLDE TIFHLNPSGRFVI Sbjct: 181 GAMVPVRVHTVVISTQHDETVTNDQIAADLKEHVIKPVIPEKYLDERTIFHLNPSGRFVI 240 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKSI+A+GLAR Sbjct: 241 GGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVANGLAR 300 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN- 997 RCIVQ+SYAIGVPEPLSVFVD+YGTGKIPD+EILK+VKENFDFRPGMI+INLDLK+GG+ Sbjct: 301 RCIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKENFDFRPGMIAINLDLKRGGSG 360 Query: 998 RFIKTAAYGHFGRDDADFTWEVVKPLKFDKAS 1093 RF+KTAAYGHFGRDD DFTWEVVKPLK++KA+ Sbjct: 361 RFLKTAAYGHFGRDDPDFTWEVVKPLKWEKAA 392
>P46611:METK_ORYSA S-adenosylmethionine synthetase 1 - Oryza sativa (Rice)| Length = 396 Score = 475 bits (1223), Expect = e-133 Identities = 258/394 (65%), Positives = 282/394 (71%), Gaps = 59/394 (14%) Frame = +2 Query: 92 AAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITT 271 A +TFLFTSESVNEGHPDKLCDQVSDAVLDACLA+D DSKVACET TKTNMVMV GEITT Sbjct: 3 ALDTFLFTSESVNEGHPDKLCDQVSDAVLDACLAEDPDSKVACETCTKTNMVMVFGEITT 62 Query: 272 KATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPD---------------IA 406 KA VDYEKIVR+TCRNIGF+S DVGLDAD CKVLVNIEQQSPD I Sbjct: 63 KANVDYEKIVRETCRNIGFVSADVGLDADHCKVLVNIEQQSPDIAQGVHGHFTKRPEEIG 122 Query: 407 QGVHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATD 490 G GH + PE ++GA G + Y + Sbjct: 123 AGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYRNE 182 Query: 491 ETPELMPLSH-----------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFV 637 + H V ++ A LKEHVIKPVIP +YLDE TIFHLNPSGRFV Sbjct: 183 SGARVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEQYLDEKTIFHLNPSGRFV 242 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 IGGPHGDAGLTGRKIIIDTY KDPTKVDRSGAY+ARQAAKSI+ASGLA Sbjct: 243 IGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYVARQAAKSIVASGLA 302 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 RRCIVQ+SYAIGVPEPLSVFVD+YGTG+IPD+EILK+VKENFDFRPGMI INLDLKKGGN Sbjct: 303 RRCIVQVSYAIGVPEPLSVFVDTYGTGRIPDKEILKIVKENFDFRPGMIIINLDLKKGGN 362 Query: 998 -RFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 R++KTAAYGHFGRDD DFTWEVVKPLK++K SA Sbjct: 363 GRYLKTAAYGHFGRDDPDFTWEVVKPLKWEKPSA 396
>P43281:METL_SOLLC S-adenosylmethionine synthetase 2 - Solanum lycopersicum (Tomato)| (Lycopersicon esculentum) Length = 393 Score = 471 bits (1211), Expect = e-132 Identities = 257/393 (65%), Positives = 279/393 (70%), Gaps = 60/393 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQD +SKVACET TKTN+VMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDPESKVACETCTKTNLVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPD---------------IAQG 412 +DYEKIVRDTCR IGF+S DVGLDAD C+VLVNIEQQSPD I G Sbjct: 62 NIDYEKIVRDTCREIGFVSPDVGLDADNCRVLVNIEQQSPDIAQGVHGHLTKRPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y D Sbjct: 122 DQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCSWLRPDGKTQVTVEYHNDNG 181 Query: 497 PELMPL------------SHVLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 ++PL V ++ LKEHVIKPVIP KYLDENTIFHLNPSGRFVI Sbjct: 182 A-MVPLRVHTVLISTQHDETVTNDEIARDLKEHVIKPVIPEKYLDENTIFHLNPSGRFVI 240 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKSI+A+GLAR Sbjct: 241 GGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVANGLAR 300 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN- 997 RCIVQ+SYAIGVPEPLSVFVD+YGTGKIPD+EIL +VKENFDFRPGMISINLDL +GGN Sbjct: 301 RCIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILNIVKENFDFRPGMISINLDLLRGGNG 360 Query: 998 RFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 RF+KTAAYGHFGRDD DFTWEVVKPLK+DK A Sbjct: 361 RFLKTAAYGHFGRDDPDFTWEVVKPLKWDKPEA 393
>P17562:METL_ARATH S-adenosylmethionine synthetase 2 - Arabidopsis thaliana (Mouse-ear| cress) Length = 393 Score = 469 bits (1207), Expect = e-131 Identities = 253/392 (64%), Positives = 279/392 (71%), Gaps = 59/392 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQ+SDAVLDACL QD DSKVACET TKTNMVMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQ---------------G 412 T+DYEKIVRDTCR+IGFISDDVGLDAD+CKVLVNIEQQSPDIAQ G Sbjct: 62 TIDYEKIVRDTCRSIGFISDDVGLDADKCKVLVNIEQQSPDIAQGVHGHFTKRPEDIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y D Sbjct: 122 DQGHMFGYATDETPELMPLSHVLATKIGARLTEVRKNGTCRWLRPDGKTQVTVEYYNDNG 181 Query: 497 PELMPLSH-----------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 + H V ++ LKEHVIKP+IP KYLD+ TIFHLNPSGRFVIG Sbjct: 182 AMVPVRVHTVLISTQHDETVTNDEIARDLKEHVIKPIIPEKYLDDKTIFHLNPSGRFVIG 241 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKS++A+G+ARR Sbjct: 242 GPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVANGMARR 301 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN-R 1000 +VQ+SYAIGVPEPLSVFVD+YGTG IPD+EILK+VKE FDFRPGM++INLDLK+GGN R Sbjct: 302 ALVQVSYAIGVPEPLSVFVDTYGTGLIPDKEILKIVKETFDFRPGMMTINLDLKRGGNGR 361 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 F KTAAYGHFGRDD DFTWEVVKPLK+DK A Sbjct: 362 FQKTAAYGHFGRDDPDFTWEVVKPLKWDKPQA 393
>P47916:METK_POPDE S-adenosylmethionine synthetase - Populus deltoides (Eastern poplar)| (Eastern cottonwood) Length = 395 Score = 469 bits (1207), Expect = e-131 Identities = 257/390 (65%), Positives = 280/390 (71%), Gaps = 60/390 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 AETFLFTSESVNEGHPDKLCDQ+SDAVLDACLAQD DSKVACET TKTNMVMV GEITTK Sbjct: 2 AETFLFTSESVNEGHPDKLCDQISDAVLDACLAQDPDSKVACETCTKTNMVMVFGEITTK 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSP---------------DIAQ 409 A VDYEKIVRDTCRNIGF S DVGLDAD CKVLVNIEQQSP +I Sbjct: 62 ADVDYEKIVRDTCRNIGFTSADVGLDADNCKVLVNIEQQSPDIAQGVHGHFSKRPEEIGA 121 Query: 410 GVHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDE 493 G GH + PE ++GA G + Y +E Sbjct: 122 GDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYY-NE 180 Query: 494 TPELMPL------------SHVLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFV 637 ++P+ V ++ A LKEHVIKPVIP KYLDE TIFHLNPSGRFV Sbjct: 181 NGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFV 240 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 IGGPHG++GLTGRKIIIDTY KDPTKVDRSGAYI RQAAKSI+ASGLA Sbjct: 241 IGGPHGESGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASGLA 300 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 RRCIVQ+SYAIGVPEPLSVFVD+YGTGKIPD+EIL++VKE FDFRPGMISINLDLK+GGN Sbjct: 301 RRCIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILQIVKERFDFRPGMISINLDLKRGGN 360 Query: 998 -RFIKTAAYGHFGRDDADFTWEVVKPLKFD 1084 RF+KTAAYGHFGRDD DFTWEVVKPLK+D Sbjct: 361 SRFLKTAAYGHFGRDDPDFTWEVVKPLKWD 390
>O22338:METK_MUSAC S-adenosylmethionine synthetase - Musa acuminata (Banana)| Length = 393 Score = 468 bits (1205), Expect = e-131 Identities = 251/391 (64%), Positives = 278/391 (71%), Gaps = 58/391 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 +TFLFTSESVNEGHPDKLCDQ+SDAVLDACL QD DSKVACET TKTNMVMV GEITTK Sbjct: 3 DTFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKG 62 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQ---------------G 412 +DYEKIVRDTCR+IGF S+DVGLDAD CKVLVNIEQQSPDIAQ G Sbjct: 63 NIDYEKIVRDTCRDIGFTSEDVGLDADHCKVLVNIEQQSPDIAQGVHGHFTKRPEEIGAG 122 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y D Sbjct: 123 DQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYRNDHG 182 Query: 497 PELMPLSH-----------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 + H V ++ A LKEHVIKPVIP +YLDE TIFHLNPSGRFVIG Sbjct: 183 AMIPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEQYLDEKTIFHLNPSGRFVIG 242 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GPHGDAGLTGRKIIIDTY KDPTKVDRSGAY+ARQAAKSI+AS LARR Sbjct: 243 GPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYVARQAAKSIVASELARR 302 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRF 1003 CIVQ+SYAIGVPEPLSVFVD+YGTGKIPD+EILK+VKENFDFRPG+I+INL LK+GG R+ Sbjct: 303 CIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKENFDFRPGLITINLGLKRGGYRY 362 Query: 1004 IKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 +KTAAYGHFGRDD DFTWEVVKPL+ +K +A Sbjct: 363 LKTAAYGHFGRDDPDFTWEVVKPLELEKPAA 393
>P24260:METL_DIACA S-adenosylmethionine synthetase 2 - Dianthus caryophyllus (Carnation)| (Clove pink) Length = 396 Score = 468 bits (1204), Expect = e-131 Identities = 256/394 (64%), Positives = 280/394 (71%), Gaps = 59/394 (14%) Frame = +2 Query: 92 AAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITT 271 AA+TFLFTSESVNEGHPDKLCDQ+SDAVLDACLAQDA+SKVACET TKTN+VMV GEITT Sbjct: 4 AADTFLFTSESVNEGHPDKLCDQISDAVLDACLAQDAESKVACETCTKTNLVMVFGEITT 63 Query: 272 KATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPD---------------IA 406 KA VDYEKIV DTCR IGF+S DVGLDAD CKVLV IEQQSPD I Sbjct: 64 KANVDYEKIVADTCREIGFVSPDVGLDADNCKVLVYIEQQSPDIAQGVHGHLTKRPEDIG 123 Query: 407 QGVHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATD 490 G GH + PE ++GA G + Y + Sbjct: 124 AGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYY-N 182 Query: 491 ETPELMPL------------SHVLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRF 634 E ++P+ V ++ A LKEHVIKPVIP KYLDENTIFHLNPSGRF Sbjct: 183 ENGAMVPIRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDENTIFHLNPSGRF 242 Query: 635 VIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGL 814 VIGGPHGDAGLTGRKIIIDTY KDPTKVDRSGAYIARQAAKSI+ASGL Sbjct: 243 VIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSRKDPTKVDRSGAYIARQAAKSIVASGL 302 Query: 815 ARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGG 994 ARRCIVQISYAIGVPEPLSVFVD+YGTGKI DREILK+VKENFDFRPGMI+I LDLKKGG Sbjct: 303 ARRCIVQISYAIGVPEPLSVFVDTYGTGKIHDREILKIVKENFDFRPGMIAIALDLKKGG 362 Query: 995 NRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 NR++KTAAYGHFGR+D DFTWE K LK++K A Sbjct: 363 NRYLKTAAYGHFGREDPDFTWEAAKTLKWEKPQA 396
>P49611:METK_BRAJU S-adenosylmethionine synthetase - Brassica juncea (Leaf mustard)| (Indian mustard) Length = 393 Score = 466 bits (1198), Expect = e-130 Identities = 251/392 (64%), Positives = 279/392 (71%), Gaps = 59/392 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQ+SDAVLDACL QD DSKVACET TKTNMVMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQ---------------G 412 TVDYEKIVRDTCR+IGFISDDVGLDAD+CKVLVNIEQQSPDIAQ G Sbjct: 62 TVDYEKIVRDTCRSIGFISDDVGLDADKCKVLVNIEQQSPDIAQGVHGHFTKRPEDIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y D Sbjct: 122 DQGHMFGYATDETPELMPLSHVLATKIGAKLTEVRKNGTCRWLRPDGKTQVTVEYYNDNG 181 Query: 497 PELMPLSH-----------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 + H V ++ LKEHVIKP+IP KYLD+ TIFHLNPSGRFVIG Sbjct: 182 AMVPVRVHTVLISTQHDETVTNEEIARDLKEHVIKPIIPEKYLDDKTIFHLNPSGRFVIG 241 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GP GDAGLTGRKIIIDTY KDPTKVDRSGAYI RQ+AKS++A+G+ARR Sbjct: 242 GPDGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQSAKSVVANGMARR 301 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN-R 1000 +VQ+SYAIGVPEP SVFVD+YGTG IPD+EILK+VKE+FDFRPGM++INLDLK+GGN R Sbjct: 302 ALVQVSYAIGVPEPFSVFVDTYGTGLIPDKEILKIVKESFDFRPGMMTINLDLKRGGNGR 361 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 F+KTAAYGHFGRDD DFTWEVVKPLK+DK A Sbjct: 362 FLKTAAYGHFGRDDPDFTWEVVKPLKWDKPQA 393
>P50300:METK_PINBN S-adenosylmethionine synthetase - Pinus banksiana (Jack pine)| Length = 393 Score = 464 bits (1194), Expect = e-130 Identities = 257/392 (65%), Positives = 278/392 (70%), Gaps = 59/392 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQ+SDAVLDACLAQD DSKVACET TKTNMVMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQISDAVLDACLAQDPDSKVACETCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPD---------------IAQG 412 VDYE+IVR TCR IGFISDDVGLDAD CKVLVNIEQQSPD I G Sbjct: 62 DVDYEQIVRKTCREIGFISDDVGLDADHCKVLVNIEQQSPDIAQGVHGHFTKRPEEIGAG 121 Query: 413 VHGH-FTKRPEE--------------VGA-----------------GDQGIMFGYATDE- 493 GH F +E +GA G + Y D Sbjct: 122 DQGHMFGYATDETLELMPKCHVLATKLGAKLTEVRKNGTCPWLRPHGKTQVTVEYRNDNG 181 Query: 494 --TPE-----LMPLSH---VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 PE L+ H V ++ LKEHVIKPVIP KYLDENTIFHLNPSGRFVIG Sbjct: 182 AMVPERVHTVLISTQHDETVPNDEIAPDLKEHVIKPVIPEKYLDENTIFHLNPSGRFVIG 241 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKSI+A+GLARR Sbjct: 242 GPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVANGLARR 301 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN-R 1000 CIVQ+SYAIGVPEPLS+FVD+YGTG IPD+EIL+++KE+FDFRPGMISINLDLK+GGN R Sbjct: 302 CIVQVSYAIGVPEPLSLFVDTYGTGSIPDKEILEIIKEHFDFRPGMISINLDLKRGGNGR 361 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 KTAAYGHFGRDD DFTWE VKPLK++KA A Sbjct: 362 SQKTAAYGHFGRDDPDFTWETVKPLKWEKAQA 393
>P23686:METK_ARATH S-adenosylmethionine synthetase 1 - Arabidopsis thaliana (Mouse-ear| cress) Length = 393 Score = 464 bits (1194), Expect = e-130 Identities = 252/392 (64%), Positives = 278/392 (70%), Gaps = 59/392 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQ+SDAVLDACL QD DSKVACET TKTNMVMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPD---------------IAQG 412 TVDYEKIVRDTCR IGF+SDDVGLDAD+CKVLVNIEQQSPD I G Sbjct: 62 TVDYEKIVRDTCRAIGFVSDDVGLDADKCKVLVNIEQQSPDIAQGVHGHFTKCPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y D+ Sbjct: 122 DQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYYNDKG 181 Query: 497 PELMPLSH-----------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 + H V ++ LKEHVIKPVIP KYLDE TIFHLNPSGRFVIG Sbjct: 182 AMVPIRVHTVLISTQHDETVTNDEIARDLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIG 241 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKS++A+G+ARR Sbjct: 242 GPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVANGMARR 301 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN-R 1000 +VQ+SYAIGVPEPLSVFVD+Y TG IPD+EILK+VKE+FDFRPGM++INLDLK+GGN R Sbjct: 302 ALVQVSYAIGVPEPLSVFVDTYETGLIPDKEILKIVKESFDFRPGMMTINLDLKRGGNGR 361 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 F+KTAAYGHFGRDD DFTWEVVKPLK+DK A Sbjct: 362 FLKTAAYGHFGRDDPDFTWEVVKPLKWDKPQA 393
>P93254:METK_MESCR S-adenosylmethionine synthetase - Mesembryanthemum crystallinum| (Common ice plant) Length = 392 Score = 463 bits (1191), Expect = e-130 Identities = 251/389 (64%), Positives = 279/389 (71%), Gaps = 59/389 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 +TFLFTSESVNEGHPDKLCDQ+SDAVLDACLAQDA+SKVACET TKTN+VMV GEITTKA Sbjct: 2 DTFLFTSESVNEGHPDKLCDQISDAVLDACLAQDAESKVACETCTKTNLVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSP---------------DIAQG 412 VDYEKI RDTCRNIGF+SDDVGLDAD CKVLV IEQQSP +I G Sbjct: 62 NVDYEKIARDTCRNIGFVSDDVGLDADNCKVLVYIEQQSPDIAQGVHGHLTKRPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y +E Sbjct: 122 DQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYY-NEN 180 Query: 497 PELMPL------------SHVLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 ++P+ V ++ A LKEHVIKPVIP KYLDE TIFHLNPSGRFVI Sbjct: 181 GAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVI 240 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGPHGDAGLTGRKIIIDTY KDPTKVDRSGAYIARQAAKSI+A+GLAR Sbjct: 241 GGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIARQAAKSIVAAGLAR 300 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 RCIVQISYAIGV EPLSVFVD+YGTGKI D++ILK+VKE FDFRPGMI+ NLDL +GGNR Sbjct: 301 RCIVQISYAIGVAEPLSVFVDTYGTGKISDKDILKIVKETFDFRPGMIANNLDLLRGGNR 360 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDK 1087 ++KTAAYGHFGRDDADFTWEVVKPLK++K Sbjct: 361 YLKTAAYGHFGRDDADFTWEVVKPLKWEK 389
>P43282:METM_SOLLC S-adenosylmethionine synthetase 3 - Solanum lycopersicum (Tomato)| (Lycopersicon esculentum) Length = 390 Score = 450 bits (1158), Expect = e-126 Identities = 248/386 (64%), Positives = 268/386 (69%), Gaps = 59/386 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQVSDA+LDACL QD +SKVACET TKTNMVMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQVSDAILDACLEQDPESKVACETCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPD---------------IAQG 412 TVDYEKIVRDTCR IGF+S DVGLDAD CKVLVNIEQQSPD I G Sbjct: 62 TVDYEKIVRDTCRGIGFVSADVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKKPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y D Sbjct: 122 DQGHMFGYATDETPELMPLTHVLATKLGAKLTEVRKNKTCPWLRPDGKTQVTVEYKNDNG 181 Query: 497 PELMPLSH-----------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 + H V ++ LKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG Sbjct: 182 AMVPIRVHTVLISTQHDETVTNDQIAQDLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 241 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKS++ASGLARR Sbjct: 242 GPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVASGLARR 301 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN-R 1000 CIVQ+SYAIGV EPLSVFVD+Y TG IPD++IL L+KENFDFRPGM+SINLDL +GGN R Sbjct: 302 CIVQVSYAIGVAEPLSVFVDTYKTGTIPDKDILVLIKENFDFRPGMMSINLDLLRGGNYR 361 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLK 1078 + KTAAYGHFGRDD DFTWE VK LK Sbjct: 362 YQKTAAYGHFGRDDPDFTWETVKVLK 387
>P48498:METK_PETHY S-adenosylmethionine synthetase - Petunia hybrida (Petunia)| Length = 390 Score = 449 bits (1156), Expect = e-125 Identities = 246/385 (63%), Positives = 268/385 (69%), Gaps = 59/385 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQVSDA+LDACL QD +SKVACET TKTNMVMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQVSDAILDACLEQDPESKVACETCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQ---------------G 412 TVDYEKIVRDTCR IGF S DVGLDAD CKVLVNIEQQSPDIAQ G Sbjct: 62 TVDYEKIVRDTCRGIGFTSADVGLDADHCKVLVNIEQQSPDIAQGVHGHLTKKPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y D Sbjct: 122 DQGHMFGYATDETPELMPLTHVWATKLGAKLTEVRKNKTCPWLRPDGKTQVTVEYRNDNG 181 Query: 497 PELMPLSHVLAT-----------KLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 + H + ++ LKEHVIKPV+PA+YLDENTIFHLNPSGRFVIG Sbjct: 182 AMIPLRVHTILISTQHDETVTNDQIAQDLKEHVIKPVVPAEYLDENTIFHLNPSGRFVIG 241 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKS++ASGLARR Sbjct: 242 GPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVASGLARR 301 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN-R 1000 CIVQ+SYAIGV EPLSVFVD+Y TG IPD++IL L+KENFDFRPGM+SINLDL +GGN R Sbjct: 302 CIVQVSYAIGVAEPLSVFVDTYKTGTIPDKDILTLIKENFDFRPGMMSINLDLLRGGNFR 361 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPL 1075 + KTAAYGHFGRDD DFTWE VK L Sbjct: 362 YQKTAAYGHFGRDDPDFTWETVKVL 386
>P50302:METL_ACTCH S-adenosylmethionine synthetase 2 - Actinidia chinensis (Kiwi)| (Yangtao) Length = 390 Score = 442 bits (1137), Expect = e-123 Identities = 242/387 (62%), Positives = 272/387 (70%), Gaps = 60/387 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E+FLFTSESVNEGHPDKLCDQVSDA+LDACL QD +SKVACET TKTNMVMV GEITTKA Sbjct: 2 ESFLFTSESVNEGHPDKLCDQVSDAILDACLEQDPESKVACETCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSP---------------DIAQG 412 V+YEKIVRDTCR IGF S DVGLDAD CKVLVNIEQQSP +I G Sbjct: 62 KVNYEKIVRDTCRGIGFTSPDVGLDADHCKVLVNIEQQSPDIAQGVHGHLSKKPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y +E Sbjct: 122 DQGHMFGYATDETPELMPLTHVLATKLGAKLTEVRKNNTCPWLRPDGKTQVTVEYR-NEG 180 Query: 497 PELMPL------------SHVLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 ++P+ V ++ LKEHVIKPVIPA+Y+D++TIFHLNPSGRFVI Sbjct: 181 GAMVPVRVHTVLISTQHDETVTNEQIAKDLKEHVIKPVIPAQYMDDDTIFHLNPSGRFVI 240 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGPHGDAGLTGRKIIIDTY KDPTKVDRSGAY+ RQAAKS++ASGLAR Sbjct: 241 GGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYVVRQAAKSVVASGLAR 300 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN- 997 RCIVQ+SYAIGVPEPLSVFVD+Y TGKIPD++IL L+KENFDFRPGMI+INLDLK+GGN Sbjct: 301 RCIVQVSYAIGVPEPLSVFVDTYKTGKIPDKDILALIKENFDFRPGMIAINLDLKRGGNF 360 Query: 998 RFIKTAAYGHFGRDDADFTWEVVKPLK 1078 R+ KTAAYGHFGRDDAD TWE VK LK Sbjct: 361 RYQKTAAYGHFGRDDADLTWETVKILK 387
>Q96553:METM_CATRO S-adenosylmethionine synthetase 3 - Catharanthus roseus (Rosy| periwinkle) (Madagascar periwinkle) Length = 390 Score = 437 bits (1123), Expect = e-122 Identities = 241/387 (62%), Positives = 269/387 (69%), Gaps = 60/387 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETFLFTSESVNEGHPDKLCDQVSDA+LDACL QD +SKVACET TKTNMVMV GEITTKA Sbjct: 2 ETFLFTSESVNEGHPDKLCDQVSDAILDACLEQDPESKVACETCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSP---------------DIAQG 412 TV+YEKIVRDTCR IGF S DVGLDAD CKVLVNIEQQSP +I G Sbjct: 62 TVNYEKIVRDTCRGIGFTSPDVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKKPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y +E Sbjct: 122 DQGHMFGYATDETPELMPLTHVLATKLGAKLTEVRKNKTCPWLRPDGKTQVTVEYR-NEG 180 Query: 497 PELMPL------------SHVLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 ++P+ V ++ LKEHVIKPVIPA+YLD+ TIFHLNPSGRFVI Sbjct: 181 GAMVPIRVHTVLISTQHDETVTNEQIAQDLKEHVIKPVIPAQYLDDQTIFHLNPSGRFVI 240 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKS++ASGLAR Sbjct: 241 GGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVASGLAR 300 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN- 997 RC+VQ+SYAIGV EPLSVFVD++ TGKIPD++IL L+KENFDFRPGMI+INLDLK+GGN Sbjct: 301 RCLVQVSYAIGVAEPLSVFVDTFKTGKIPDKDILALIKENFDFRPGMIAINLDLKRGGNF 360 Query: 998 RFIKTAAYGHFGRDDADFTWEVVKPLK 1078 R+ KTAA GH GRDD DFTWE VK LK Sbjct: 361 RYQKTAALGHLGRDDPDFTWETVKILK 387
>P50301:METK_ACTCH S-adenosylmethionine synthetase 1 - Actinidia chinensis (Kiwi)| (Yangtao) Length = 390 Score = 436 bits (1120), Expect = e-121 Identities = 239/387 (61%), Positives = 270/387 (69%), Gaps = 60/387 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 +TFLFTSESVNEGHPDKLCDQVSDA+LDACL QD +SKVACE+ TKTNMVMV GEITTKA Sbjct: 2 DTFLFTSESVNEGHPDKLCDQVSDAILDACLKQDPESKVACESCTKTNMVMVFGEITTKA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSP---------------DIAQG 412 V+YEKIVRDTCR IGF S DVGLDAD CKVLVNIEQQSP +I G Sbjct: 62 QVNYEKIVRDTCRGIGFTSPDVGLDADHCKVLVNIEQQSPDIAQGVHGHLTKKPEEIGAG 121 Query: 413 VHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYATDET 496 GH + PE ++GA G + Y +E Sbjct: 122 DQGHMFGYATDETPELMPLTHVLATKLGAKLTEVRKNSTCPWLRPDGKTQVTVEYR-NEG 180 Query: 497 PELMPL------------SHVLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 ++P+ V ++ LK+HVIKPV+PA+YLD+NTIFHLNPSGRFVI Sbjct: 181 GAMVPIRVHTVLISTQHDETVTNDQIANDLKKHVIKPVVPAQYLDDNTIFHLNPSGRFVI 240 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKS++ASGLAR Sbjct: 241 GGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVASGLAR 300 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN- 997 RC+VQ+SYAIGV EPLSVFVD+Y TGKI D++IL L+KENFDFRPGMI+INLDLK+GGN Sbjct: 301 RCLVQVSYAIGVAEPLSVFVDTYKTGKIADKDILALIKENFDFRPGMIAINLDLKRGGNL 360 Query: 998 RFIKTAAYGHFGRDDADFTWEVVKPLK 1078 R+ KTAAYGHFGRDD DFTWE VK LK Sbjct: 361 RYQKTAAYGHFGRDDPDFTWETVKILK 387
>P49613:METL_PEA S-adenosylmethionine synthetase 2 - Pisum sativum (Garden pea)| Length = 374 Score = 414 bits (1063), Expect = e-115 Identities = 232/373 (62%), Positives = 253/373 (67%), Gaps = 59/373 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MA ETFLFTSESVNEGHPDKLCDQ+SDAVLDACL QD +SKVACET TKTNMVMV GEIT Sbjct: 1 MATETFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPESKVACETCTKTNMVMVFGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPD---------------I 403 TKA VDYEKIVRDTCRNIGF+SDDVGLDAD CKVLVNIEQQSPD I Sbjct: 61 TKANVDYEKIVRDTCRNIGFVSDDVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKRPEDI 120 Query: 404 AQGVHGHF-----TKRPE----------EVGA-----------------GDQGIMFGYAT 487 G GH + PE ++GA G + Y Sbjct: 121 GAGDQGHMFGYATDETPEFMPLSHVLATKLGASLTEVRKNGTCPWLRPDGKTQVTVEYYN 180 Query: 488 DETPELMPLSH-----------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRF 634 D+ + H V ++ A LKEHVIKPVIP KYLDE TIFHLNPSGRF Sbjct: 181 DKGAMVPIRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRF 240 Query: 635 VIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGL 814 GGPHGDAGLTGRKIIIDTY KDPTKVDRSGAYI R+AAKSI+A+GL Sbjct: 241 RHGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVREAAKSIVANGL 300 Query: 815 ARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGG 994 ARRC+VQ+SYAIGVPEPLSVFVDSYGTGKIPDREIL +VKE FDFRPGMISI+LDL +GG Sbjct: 301 ARRCLVQVSYAIGVPEPLSVFVDSYGTGKIPDREILNIVKEAFDFRPGMISISLDLLRGG 360 Query: 995 N-RFIKTAAYGHF 1030 N RF + + F Sbjct: 361 NGRFFEDSCIWTF 373
>P50303:METM_ACTCH S-adenosylmethionine synthetase 3 - Actinidia chinensis (Kiwi)| (Yangtao) Length = 360 Score = 413 bits (1061), Expect = e-114 Identities = 227/358 (63%), Positives = 251/358 (70%), Gaps = 60/358 (16%) Frame = +2 Query: 194 QDADSKVACETVTKTNMVMVLGEITTKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVL 373 QD DSKVACET TKTNMVMV GEITTK +DYEKIVRDTCRNIGF+SDDVGLDAD CKVL Sbjct: 1 QDPDSKVACETCTKTNMVMVFGEITTKGNIDYEKIVRDTCRNIGFVSDDVGLDADNCKVL 60 Query: 374 VNIEQQSPD---------------IAQGVHGHF-----TKRPE----------EVGA--- 454 VNIEQQSPD I G GH + PE ++GA Sbjct: 61 VNIEQQSPDIAQGVHGHLTKRPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLT 120 Query: 455 --------------GDQGIMFGYATDETPELMPL------------SHVLATKLGARLKE 556 G + Y +E ++P+ V K+ A LKE Sbjct: 121 EVRKDGTCPWLRPDGKTQVTIEYY-NENGAMVPIRVHTVLISTQHDETVTNDKIAADLKE 179 Query: 557 HVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXX 736 HVI+PVIP KYLDE TIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTY Sbjct: 180 HVIRPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSG 239 Query: 737 KDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDRE 916 KDPTKVDRSGAYI RQAAKSI+ASGLARRCIVQ+SYAIGVPEPLSVFVD+YGTGKIPD+E Sbjct: 240 KDPTKVDRSGAYIVRQAAKSIVASGLARRCIVQVSYAIGVPEPLSVFVDTYGTGKIPDKE 299 Query: 917 ILKLVKENFDFRPGMISINLDLKKGGN-RFIKTAAYGHFGRDDADFTWEVVKPLKFDK 1087 ILK+VKE+FDFRPGMI+I+LDLK+GGN RF+KTAAYGHFGRDDADFTWEVVKPLK++K Sbjct: 300 ILKIVKESFDFRPGMIAIHLDLKRGGNGRFLKTAAYGHFGRDDADFTWEVVKPLKWEK 357
>P49612:METK_PEA S-adenosylmethionine synthetase 1 - Pisum sativum (Garden pea)| Length = 366 Score = 405 bits (1042), Expect = e-112 Identities = 227/364 (62%), Positives = 250/364 (68%), Gaps = 59/364 (16%) Frame = +2 Query: 176 LDACLAQDADSKVACETVTKTNMVMVLGEITTKATVDYEKIVRDTCRNIGFISDDVGLDA 355 +DACL QD+DSKVACET TKTN+VMV GEITTKA VDYEKIVR+TCRNIGF+S DVGLDA Sbjct: 3 VDACLEQDSDSKVACETCTKTNLVMVFGEITTKANVDYEKIVRNTCRNIGFVSADVGLDA 62 Query: 356 DRCKVLVNIEQQSPDIAQ---------------GVHGHF-----TKRPE----------E 445 D CKVLVNIEQQSPDIAQ G GH + PE + Sbjct: 63 DNCKVLVNIEQQSPDIAQGVHGHFTKKPEEIGAGDQGHMFGYATDETPELMPLSHVLATK 122 Query: 446 VGA-----------------GDQGIMFGYATDETPELMPLSH-----------VLATKLG 541 +GA G+ + Y D+ + H V ++ Sbjct: 123 LGARLTEVRKNGTCAWLRPDGNTQVTVEYYNDKGAMVPIRVHTVLISTQHDETVTNDEIA 182 Query: 542 ARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXX 721 A LKEHVIKPVIP KYLD TI HLNPSGRFVIGGPHGDAGLTGRKIIIDTY Sbjct: 183 ADLKEHVIKPVIPEKYLDSKTICHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGG 242 Query: 722 XXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGK 901 KDPTKVDR GAYI RQAAKSI+ASGLARR IVQ+ AIGVPEPLSVFVD+YGTGK Sbjct: 243 GAFSGKDPTKVDRRGAYIVRQAAKSIVASGLARRAIVQLLRAIGVPEPLSVFVDTYGTGK 302 Query: 902 IPDREILKLVKENFDFRPGMISINLDLKKGGN-RFIKTAAYGHFGRDDADFTWEVVKPLK 1078 IPDREILK+VKE FDFRPGMISINLDL +GGN RF+KTAAYGHFGR+D DFTWEVVKPLK Sbjct: 303 IPDREILKIVKETFDFRPGMISINLDLLRGGNGRFLKTAAYGHFGREDPDFTWEVVKPLK 362 Query: 1079 FDKA 1090 ++KA Sbjct: 363 WEKA 366
>Q27522:METN_CAEEL Probable S-adenosylmethionine synthetase tag-32 - Caenorhabditis| elegans Length = 404 Score = 351 bits (900), Expect = 5e-96 Identities = 199/391 (50%), Positives = 240/391 (61%), Gaps = 58/391 (14%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ FLFTSESV+EGHPDK+CDQ+SDAVLDA LAQD +KVACETVTKT M+M+ GEIT Sbjct: 1 MSKNKFLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV 448 +KA VDY+ +VR+ + IG+ G D C VLV +EQQSP+IA GVH K +V Sbjct: 61 SKAVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVH--VDKDIADV 118 Query: 449 GAGDQGIMFGYATDETPELMP----LSH-------------------------------- 520 GAGDQGIMFGYATDET E MP LSH Sbjct: 119 GAGDQGIMFGYATDETEEAMPLTLLLSHKLNYKLHELRRSGELEWVRPDSKTQVTIEYSS 178 Query: 521 -------------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRF 634 V++T+ L L E VIK VIP +D +T++HLNP G F Sbjct: 179 EGGACVPLRVHTVVISTQHSPDISLEDLRKELIEKVIKVVIPGNLIDNDTVYHLNPCGSF 238 Query: 635 VIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGL 814 V+GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AKS++ +GL Sbjct: 239 VVGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGL 298 Query: 815 ARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGG 994 RRC+VQ+SYAIGV +PLSV V S+GT + + E+LK+V +NFD RPGMI NLDLK+ Sbjct: 299 CRRCLVQVSYAIGVAKPLSVMVFSFGTSALNEAELLKIVNDNFDLRPGMIIKNLDLKRA- 357 Query: 995 NRFIKTAAYGHFGRDDADFTWEVVKPLKFDK 1087 + TA GHFG + DF WE + LK DK Sbjct: 358 -IYEPTAENGHFGHN--DFPWEQARKLKIDK 385
>O60198:METK_SCHPO S-adenosylmethionine synthetase - Schizosaccharomyces pombe (Fission| yeast) Length = 382 Score = 349 bits (896), Expect = 1e-95 Identities = 190/387 (49%), Positives = 244/387 (63%), Gaps = 58/387 (14%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A+TFLFTSESV EGHPDK+CDQ+SDA+LDACL D SKVACET +KT MVMV GEITT+ Sbjct: 2 AQTFLFTSESVGEGHPDKICDQISDAILDACLKDDPFSKVACETASKTGMVMVFGEITTR 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 + +DY+K++R+T ++IG+ + G D C VLV IEQQSPDIAQG+ H+ K EE+GA Sbjct: 62 SQIDYQKVIRNTIKSIGYDDSEKGFDYKTCNVLVAIEQQSPDIAQGL--HYEKALEELGA 119 Query: 455 GDQGIMFGYATDETPELMPLSHVLATKL-------------------------------- 538 GDQGIMFGYATDETPE +PL+ +LA KL Sbjct: 120 GDQGIMFGYATDETPEKLPLTILLAHKLNAAMSVARRDGSLPWLRPDTKTQVTIEYEEEN 179 Query: 539 GARLKEHVIKPVIPAKYLD--------------------------ENTIFHLNPSGRFVI 640 GA + V V+ A++ D E T++H+ PSGRFV+ Sbjct: 180 GAVIPRRVDTIVVSAQHADSISTEDLRSEILEKIIKPTVPAHLLDEKTVYHIQPSGRFVV 239 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KD +KVDRS AY AR AKS++A+GLAR Sbjct: 240 GGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYSKVDRSAAYAARWIAKSLVAAGLAR 299 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 RC+VQ+SYAIGV EPLS+FV++YGT E+++++++NFD RPG++ +L L+ Sbjct: 300 RCLVQLSYAIGVAEPLSIFVNTYGTSSKTSAELVEIIRKNFDLRPGVLVKSLKLQT--PF 357 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKF 1081 ++ TA+YGHF D WE K LKF Sbjct: 358 YLSTASYGHF--TDQSKPWEQPKELKF 382
>P50305:METK_CAEEL Probable S-adenosylmethionine synthetase C06E7.1 - Caenorhabditis| elegans Length = 404 Score = 348 bits (894), Expect = 2e-95 Identities = 199/390 (51%), Positives = 241/390 (61%), Gaps = 58/390 (14%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ FLFTSESV+EGHPDK+CDQ+SDAVLDA LAQD +KVACETVTKT M+M+ GEIT Sbjct: 1 MSQHKFLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV 448 +KA VDY+ +VR+ + IG+ G D C VLV +EQQSP+IA GVH K ++V Sbjct: 61 SKAVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVH--VDKDSDDV 118 Query: 449 GAGDQGIMFGYATDETPELMP----LSH-------------------------------- 520 GAGDQGIMFGYATDET E MP LSH Sbjct: 119 GAGDQGIMFGYATDETEEAMPLTLLLSHKLNRKLHELRRSGELEWVRPDSKTQVTIEYAS 178 Query: 521 -------------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRF 634 V++T+ L L E VIK VIPA +D+ TI+HLNP G F Sbjct: 179 EGGACVPLRVHTVVISTQHSPDISLDDLRKELIEKVIKAVIPANLIDDKTIYHLNPCGSF 238 Query: 635 VIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGL 814 +IGGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AKS++ SGL Sbjct: 239 IIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKSGL 298 Query: 815 ARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGG 994 RRC+VQ+SYAIGV +PLSV V S+GT + + E+LK+V +NFD RPGMI +LDLKK Sbjct: 299 CRRCLVQVSYAIGVAKPLSVMVFSFGTSALNEGELLKIVNDNFDLRPGMIIKDLDLKK-- 356 Query: 995 NRFIKTAAYGHFGRDDADFTWEVVKPLKFD 1084 + TA GHFG + +F WE + L+ D Sbjct: 357 PIYEPTAENGHFGHN--EFPWEQPRHLQID 384
>Q95032:METK_ACACA S-adenosylmethionine synthetase - Acanthamoeba castellanii (Amoeba)| Length = 388 Score = 347 bits (891), Expect = 6e-95 Identities = 197/390 (50%), Positives = 236/390 (60%), Gaps = 60/390 (15%) Frame = +2 Query: 92 AAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITT 271 +++T LFTSE V+E HPDKLCDQVSDA+LDACLA D SKVACET +KT MVMV GEITT Sbjct: 3 SSKTLLFTSECVSESHPDKLCDQVSDAILDACLANDPYSKVACETASKTGMVMVFGEITT 62 Query: 272 KATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVG 451 K++ DY+K++R+T + IGF +G D C +LV IEQQSPDIAQGVH + +++G Sbjct: 63 KSSFDYQKVIRETVKRIGFTDSSIGFDYKTCNILVAIEQQSPDIAQGVH--VGRSDDDLG 120 Query: 452 AGDQGIMFGYATD----------------------------------------------E 493 AGDQG MFG+AT+ E Sbjct: 121 AGDQGHMFGHATNETPEFMPMTHVLATRLCQRMTEVRNNSILSWMRPDAKTQVTVEYRNE 180 Query: 494 TPELMPLSH------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFV 637 L+PL V ++ RL E VIKP IPA LD TIFHLNPSGRFV Sbjct: 181 NGTLIPLRRHTVVISVQHSEDVTNEEIRKRLMEEVIKPSIPAHLLDGETIFHLNPSGRFV 240 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 IGGP G+AGLTG KIIIDTY KDP+KVDRS AY AR AKS++A GLA Sbjct: 241 IGGPQGEAGLTGGKIIIDTYGGWGAHGGGAFSGKDPSKVDRSAAYAARWIAKSLVARGLA 300 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGT--GKIPDREILKLVKENFDFRPGMISINLDLKKG 991 R +VQ+SYAIGV PLSVFVDSYGT G D ++L + K NFD RPG I +L L++ Sbjct: 301 NRALVQVSYAIGVSHPLSVFVDSYGTAQGGRTDEDLLAISKSNFDLRPGKIINDLQLRR- 359 Query: 992 GNRFIKTAAYGHFGRDDADFTWEVVKPLKF 1081 + KTA +GHFGR+D DF WE K L F Sbjct: 360 -PIYEKTAYHGHFGRNDPDFLWEAPKKLNF 388
>P50304:METK_ASCIM S-adenosylmethionine synthetase - Ascobolus immersus| Length = 393 Score = 345 bits (886), Expect = 2e-94 Identities = 195/386 (50%), Positives = 243/386 (62%), Gaps = 61/386 (15%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 +FLFTSESV EGHPDK+ DQVSDAVLDACLA+D SKVACET TKT M+MV GEITTKA Sbjct: 13 SFLFTSESVGEGHPDKIADQVSDAVLDACLAEDPLSKVACETATKTGMIMVFGEITTKAH 72 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 +DY+KI+R+ ++IG+ G D C VLV IEQQSPDIAQG+ H+ K EE+GAGD Sbjct: 73 LDYQKIIRNAVKDIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGL--HYEKALEELGAGD 130 Query: 461 QGIMFGYATDETPELMPLSHVLATKLGARLK-----------------------EHVIKP 571 QGIMFGYATDETPEL+PL+ +LA +L A + EH Sbjct: 131 QGIMFGYATDETPELLPLTLLLAHQLNANMAKARRDGSLPWLRPDTKTQVTIEYEHDGGA 190 Query: 572 VIP-----------------------------------AKYLDENTIFHLNPSGRFVIGG 646 V+P AKYLDE+T+FH+ PSG F+IGG Sbjct: 191 VVPKKVKTVVVSAQHSEDITTEELRKEILEKIIKTTIPAKYLDEDTVFHIQPSGLFIIGG 250 Query: 647 PHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRC 826 P GDAGLTGRKII+DTY KD +KVDRS AY+AR AKS++ +GL RRC Sbjct: 251 PQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYSKVDRSAAYLARWIAKSLVTAGLVRRC 310 Query: 827 IVQISYAIGVPEPLSVFVDSYGT---GKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 +VQ+SYAIGV EPLS+FV+ YGT G+ D ++++++++NFD RPG+I LDL K Sbjct: 311 LVQLSYAIGVAEPLSIFVEDYGTSAEGRTSD-QLVEIIRKNFDMRPGVIVQELDLAK--P 367 Query: 998 RFIKTAAYGHFGRDDADFTWEVVKPL 1075 + +TA GHF + +F WE K L Sbjct: 368 IYFQTAKNGHF--TNQEFAWEKPKKL 391
>P50306:METL_CAEEL Probable S-adenosylmethionine synthetase C06E7.3 - Caenorhabditis| elegans Length = 404 Score = 342 bits (876), Expect = 3e-93 Identities = 195/388 (50%), Positives = 237/388 (61%), Gaps = 58/388 (14%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M FLFTSESV+EGHPDK+CDQ+SDAVLDA LAQD +KVACETVTKT M+M+ GEIT Sbjct: 1 MPQHKFLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV 448 +KA VDY+ +VR+ + IG+ G D C VLV +EQQSP+IA GVH K ++V Sbjct: 61 SKAVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVH--VDKDSDDV 118 Query: 449 GAGDQGIMFGYATDETPELMP----LSH-------------------------------- 520 GAGDQGIMFGYATDET E MP LSH Sbjct: 119 GAGDQGIMFGYATDETEEAMPLTLLLSHKLNRKLHELRRSGELEWVRPDSKTQVTIEYAS 178 Query: 521 -------------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRF 634 V++T+ L L E VIK VIPA +D+ TI+HLNP G F Sbjct: 179 EGGACVPLRVHTVVISTQHSPDISLDDLRKELIEKVIKAVIPANLIDDKTIYHLNPCGSF 238 Query: 635 VIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGL 814 +IGGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AKS++ +GL Sbjct: 239 IIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGL 298 Query: 815 ARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGG 994 RRC+VQ+SYAIGV +PLSV V S+GT + + ++L +V +NFD RPG I NLDLK+ Sbjct: 299 CRRCLVQVSYAIGVAKPLSVMVFSFGTSALSEEDLLTIVNDNFDLRPGKIIKNLDLKR-- 356 Query: 995 NRFIKTAAYGHFGRDDADFTWEVVKPLK 1078 + TA GHFG + +F WE + LK Sbjct: 357 PIYEPTAENGHFGHN--NFPWEQPRNLK 382
>P10659:METK_YEAST S-adenosylmethionine synthetase 1 - Saccharomyces cerevisiae (Baker's| yeast) Length = 382 Score = 339 bits (870), Expect = 2e-92 Identities = 192/387 (49%), Positives = 235/387 (60%), Gaps = 58/387 (14%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A TFLFTSESV EGHPDK+CDQVSDA+LDACLA+D SKVACET KT M+MV GEITTK Sbjct: 2 AGTFLFTSESVGEGHPDKICDQVSDAILDACLAEDPHSKVACETAAKTGMIMVFGEITTK 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A +DY+KIVRDT + IG+ G D C VLV IEQQSPDIAQGVH K E++GA Sbjct: 62 AQLDYQKIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGVHEE--KDLEDIGA 119 Query: 455 GDQGIMFGYATDETPELMPLSHVLATKL-------------------------------- 538 GDQGIMFGYATDETPE +PL+ +LA KL Sbjct: 120 GDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSLAWLRPDTKTQVTVEYKDDH 179 Query: 539 GARLKEHVIKPVIPAKYLD--------------------------ENTIFHLNPSGRFVI 640 G + + + V+ A++ D ENT + + PSGRFVI Sbjct: 180 GRWVPQRIDTVVVSAQHADEITTEDLRAQLKSEIIEKVIPRDMLDENTKYFIQPSGRFVI 239 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+D Y KD +KVDRS AY AR AKS++A+GL + Sbjct: 240 GGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCK 299 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 R VQ SYAIG+ EPLS+ VD+YGT D EI+ ++ +NFD RPG++ LDL + Sbjct: 300 RVQVQFSYAIGIAEPLSLHVDTYGTATKSDEEIIDIISKNFDLRPGVLVKELDLAR--PI 357 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKF 1081 ++ TA+YGHF + ++ WE K LKF Sbjct: 358 YLPTASYGHF--TNQEYPWEKPKTLKF 382
>P19358:METL_YEAST S-adenosylmethionine synthetase 2 - Saccharomyces cerevisiae (Baker's| yeast) Length = 384 Score = 337 bits (865), Expect = 6e-92 Identities = 190/387 (49%), Positives = 239/387 (61%), Gaps = 58/387 (14%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 ++TFLFTSESV EGHPDK+CDQVSDA+LDACL QD SKVACET KT M+MV GEITTK Sbjct: 4 SKTFLFTSESVGEGHPDKICDQVSDAILDACLEQDPFSKVACETAAKTGMIMVFGEITTK 63 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A +DY++IVRDT + IG+ G D C VLV IEQQSPDIAQG+ H+ K E++GA Sbjct: 64 ARLDYQQIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGL--HYEKSLEDLGA 121 Query: 455 GDQGIMFGYATDETPELMPLSHVLATKL-------------------------------- 538 GDQGIMFGYATDETPE +PL+ +LA KL Sbjct: 122 GDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSLPWLRPDTKTQVTVEYEDDN 181 Query: 539 GARLKEHVIKPVIPAKYLD--------------------------ENTIFHLNPSGRFVI 640 G + + + VI A++ D ENT + + PSGRFVI Sbjct: 182 GRWVPKRIDTVVISAQHADEISTADLRTQLQKDIVEKVIPKDMLDENTKYFIQPSGRFVI 241 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+D Y KD +KVDRS AY AR AKS++A+GL + Sbjct: 242 GGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCK 301 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 R VQ SYAIG+ EPLS+ VD+YGT D EI++++K+NFD RPG++ LDL + Sbjct: 302 RVQVQFSYAIGIAEPLSLHVDTYGTATKSDDEIIEIIKKNFDLRPGVLVKELDLAR--PI 359 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKF 1081 ++ TA+YGHF + +++WE K L+F Sbjct: 360 YLPTASYGHF--TNQEYSWEKPKKLEF 384
>P50299:METK_HORVU S-adenosylmethionine synthetase 1 - Hordeum vulgare (Barley)| Length = 394 Score = 337 bits (863), Expect = 1e-91 Identities = 168/188 (89%), Positives = 171/188 (90%) Frame = +2 Query: 533 KLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXX 712 ++ A LKEHVIKPVIP KYLDENTIFHLNPSGRFVIGGPHGDAGLT RKIIIDTY Sbjct: 207 EIAADLKEHVIKPVIPGKYLDENTIFHLNPSGRFVIGGPHGDAGLTARKIIIDTYGGWGA 266 Query: 713 XXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYG 892 KDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYG Sbjct: 267 HGGGAFSGKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYG 326 Query: 893 TGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYGHFGRDDADFTWEVVKP 1072 TGKIPDREILKLVKENFDFRPGMI+INLDLKKGGNRFIKTAAYGHFGRDDADFTWEVVKP Sbjct: 327 TGKIPDREILKLVKENFDFRPGMITINLDLKKGGNRFIKTAAYGHFGRDDADFTWEVVKP 386 Query: 1073 LKFDKASA 1096 LKFDKASA Sbjct: 387 LKFDKASA 394 Score = 301 bits (770), Expect = 6e-81 Identities = 148/156 (94%), Positives = 151/156 (96%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQD DSKVACET TKTNMVMV GEIT Sbjct: 1 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDPDSKVACETCTKTNMVMVFGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV 448 TKATVDYEKIVRDTCR+IGFISDDVGLDAD CKVLVNIEQQSPDIAQGVHGHFTKRPEEV Sbjct: 61 TKATVDYEKIVRDTCRDIGFISDDVGLDADHCKVLVNIEQQSPDIAQGVHGHFTKRPEEV 120 Query: 449 GAGDQGIMFGYATDETPELMPLSHVLATKLGARLKE 556 GAGDQGIMFGYATDETPELMPL+H+LATKLGARL E Sbjct: 121 GAGDQGIMFGYATDETPELMPLTHMLATKLGARLTE 156
>Q3AFS4:METK_CARHZ S-adenosylmethionine synthetase - Carboxydothermus hydrogenoformans| (strain Z-2901 / DSM 6008) Length = 396 Score = 336 bits (862), Expect = 1e-91 Identities = 189/390 (48%), Positives = 238/390 (61%), Gaps = 62/390 (15%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQ+SDAVLDA LAQD ++VACET T +V+V+GEITT VD Sbjct: 5 LFTSESVTEGHPDKIADQISDAVLDAILAQDPQARVACETAVTTGLVLVIGEITTSCYVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH-------GHFTKRP-E 442 K+VR+T R IG+ G D D C V+ +I++QSPDIA GV+ G T E Sbjct: 65 IPKVVRETIREIGYTRAKYGFDGDTCAVITSIDEQSPDIALGVNRALEAKTGEMTDDEIE 124 Query: 443 EVGAGDQGIMFGYATDETPELMP----LSHVLATKLGARLK------------------- 553 +GAGDQG+MFGYAT+ETPELMP L+H LA +L K Sbjct: 125 AIGAGDQGMMFGYATNETPELMPMPISLAHRLARRLAEVRKSRLLPYLRPDGKTQVTVEY 184 Query: 554 -------------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 EHV+KPVIP LDENT + +NP+GRFVI Sbjct: 185 DGDKPVRVDTIVVSTQHHPDVSQEEIRKDIIEHVVKPVIPEHLLDENTRYFVNPTGRFVI 244 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+G+A Sbjct: 245 GGPQGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAAGIAD 304 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 + +Q++YAIGV +P+S+ VD++GTGKI D +I++L+K++FD RP I LDL++ Sbjct: 305 KIEIQLAYAIGVAKPVSIMVDTFGTGKIADEKIVELIKKHFDLRPAGIIRMLDLRR--PI 362 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKA 1090 + +TAAYGHFGR D D WE + DKA Sbjct: 363 YKQTAAYGHFGRTDIDLPWE-----RIDKA 387
>Q9K7Q9:METK_BACHD S-adenosylmethionine synthetase - Bacillus halodurans| Length = 399 Score = 335 bits (858), Expect = 4e-91 Identities = 179/381 (46%), Positives = 236/381 (61%), Gaps = 63/381 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+CDQ+SD++LD L +D +++VACET T +V+V GEITT VD Sbjct: 9 LFTSESVTEGHPDKICDQISDSILDEILKEDPNARVACETSVTTGLVLVAGEITTSTYVD 68 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--------E 442 K+VRDT RNIG+ G D++ C VL +I++QSPDIAQGV+ R E Sbjct: 69 IPKVVRDTIRNIGYTRAKYGFDSETCAVLTSIDEQSPDIAQGVNQALEAREGQMTDAEIE 128 Query: 443 EVGAGDQGIMFGYATDETPELMPL----SHVLATKLG----------------------- 541 +GAGDQG+MFGYA +ETPELMPL SH LA +L Sbjct: 129 AIGAGDQGLMFGYANNETPELMPLPISLSHKLARRLSEARKGEILPYLRPDGKTQVTVEY 188 Query: 542 ----------------------------ARLKEHVIKPVIPAKYLDENTIFHLNPSGRFV 637 + LK+HVI+ V+P + +DE T + +NP+GRFV Sbjct: 189 DENDQSVRIDTIVISTQHHPEVTLEQIESDLKQHVIRSVVPEELIDEETKYFINPTGRFV 248 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 IGGP GDAGLTGRKII+DTY KDPTKVDRSGAY AR AK+I+A+GLA Sbjct: 249 IGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSGAYAARYVAKNIVAAGLA 308 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 +C VQ++YAIGV +P+S+ +D++GTG++ + +++LV+E+FD RP I LDL++ Sbjct: 309 DKCEVQLAYAIGVAKPVSISIDTFGTGQVSEARLVELVREHFDLRPAGIIKMLDLRR--P 366 Query: 998 RFIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR D + WE Sbjct: 367 IYKQTAAYGHFGRTDVELPWE 387
>Q3A388:METK_PELCD S-adenosylmethionine synthetase - Pelobacter carbinolicus (strain DSM| 2380 / Gra Bd 1) Length = 389 Score = 327 bits (839), Expect = 6e-89 Identities = 182/381 (47%), Positives = 233/381 (61%), Gaps = 57/381 (14%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M FLFTSESV+EGHPDK+ DQVSDA+LDA L QD S+VACET+ T M ++ GEIT Sbjct: 1 MPMTDFLFTSESVSEGHPDKVADQVSDAILDAILDQDRQSRVACETMVTTGMAVIAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH---GHFTKRP 439 T A V+Y K+VR+ R+IG+ +G D + C VL +I++QSPDI+QGV G F Sbjct: 61 TNARVEYPKVVREVIRDIGYNDSAMGFDWETCAVLTSIDRQSPDISQGVTEGAGLF---- 116 Query: 440 EEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK------------------ 553 +E GAGDQG+MFGYA DET LMP+ +H L ++ K Sbjct: 117 KEQGAGDQGLMFGYACDETSVLMPMPITYAHQLTQRMSEVRKSGLLTFLRPDSKSQVSVQ 176 Query: 554 --------------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFV 637 E VIK V+PA LDENT F++NP+GRFV Sbjct: 177 YINDKPVRVDTVVVSSQHAPDVAYETLREALIEEVIKKVVPADMLDENTKFYVNPTGRFV 236 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 +GGP GD GLTGRKII+DTY KDP+KVDRS +Y+AR AK+++A+ LA Sbjct: 237 VGGPQGDCGLTGRKIIVDTYGGQGSHGGGAFSGKDPSKVDRSASYMARYVAKNVVAAKLA 296 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 R+C VQI+YAIGV EP+S+ V+++GTG +P EI ++V+E FD RP I LDL + Sbjct: 297 RKCEVQIAYAIGVAEPVSIMVNTFGTGVLPSNEIARIVREEFDMRPAAIIETLDLLRPIY 356 Query: 998 RFIKTAAYGHFGRDDADFTWE 1060 R KTAAYGHFGR+ +FTWE Sbjct: 357 R--KTAAYGHFGRELPEFTWE 375
>Q88XB8:METK_LACPL S-adenosylmethionine synthetase - Lactobacillus plantarum| Length = 395 Score = 327 bits (837), Expect = 1e-88 Identities = 179/383 (46%), Positives = 233/383 (60%), Gaps = 61/383 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LAQD ++VA ET T +V+V GE++TK Sbjct: 2 SERHLFTSESVSEGHPDKIADQISDAILDAMLAQDPQARVAVETSVTTGLVLVFGEVSTK 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP----- 439 A VD +K+VRDT ++IG++ G D D C VLV++++QSPDIAQGV R Sbjct: 62 AYVDIQKVVRDTIKSIGYVDGQYGFDGDNCAVLVSLDEQSPDIAQGVDDSLETRSGDADP 121 Query: 440 -EEVGAGDQGIMFGYATDETPELMP----LSHVLATKLGARLK----------------- 553 +++GAGDQG+MFGYA +ETPELMP LSH L K+ A K Sbjct: 122 LDQIGAGDQGMMFGYAINETPELMPLPIALSHRLMRKIAALRKDGTIKWLRPDAKAQVTV 181 Query: 554 ----------------------------------EHVIKPVIPAKYLDENTIFHLNPSGR 631 + VIK V+PA LD+ T + +NP+GR Sbjct: 182 EYDEDNQPKRIDTVVLSTQHDPDVDLDTIRQTVIDQVIKAVLPADLLDDQTKYLVNPTGR 241 Query: 632 FVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASG 811 FVIGGP GDAGLTGRK+I+DTY KD TKVDRS +Y AR AK+++A+G Sbjct: 242 FVIGGPQGDAGLTGRKVIVDTYGGFAHHGGGAFSGKDATKVDRSASYAARYIAKNVVAAG 301 Query: 812 LARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKG 991 LA + VQ++YAIGV EP+S+ VD+ GTGK+ D ++ ++ENFD RP I LDL++ Sbjct: 302 LADQVEVQLAYAIGVAEPVSIAVDTAGTGKVSDEALINAIRENFDLRPAGIIKMLDLQRP 361 Query: 992 GNRFIKTAAYGHFGRDDADFTWE 1060 R +TAAYGHFGR D D WE Sbjct: 362 IYR--QTAAYGHFGRTDIDLPWE 382
>P61946:METK_GEOSL S-adenosylmethionine synthetase - Geobacter sulfurreducens| Length = 389 Score = 326 bits (835), Expect = 2e-88 Identities = 181/381 (47%), Positives = 232/381 (60%), Gaps = 57/381 (14%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M + ++FTSESV+EGHPDK+ DQVSDA+LDA L QD ++VACET+ T M ++ GEIT Sbjct: 1 MEMKDYIFTSESVSEGHPDKVADQVSDAILDAILTQDKRARVACETLVTTGMAVIAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGV---HGHFTKRP 439 T A VDY K+VR+T + IG+ +G D + C VLV+I++QSPDI+QGV G F Sbjct: 61 TTAVVDYPKVVRETIKEIGYNDSAMGFDWETCAVLVSIDKQSPDISQGVTEGEGMF---- 116 Query: 440 EEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK------------------ 553 +E GAGDQG+MFGYA +ETPELMP+ SH L KL K Sbjct: 117 KEQGAGDQGLMFGYACNETPELMPMTIMYSHRLTQKLAEVRKNGTLDFLRPDSKSQVSIQ 176 Query: 554 --------------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFV 637 E V+K +IP + +D+ T F +NP+GRFV Sbjct: 177 YVDDRPVRVDTVVISSQHTPEVSYETIKEGIIEEVVKKIIPVELMDDKTRFLINPTGRFV 236 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 IGGP GD GLTGRKII+D+Y KDP+KVDRS AY+ R AK+++A+GL Sbjct: 237 IGGPMGDCGLTGRKIIVDSYGGHGAHGGGAFSGKDPSKVDRSAAYMGRYVAKNLVAAGLC 296 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 RC VQ++YAIGV EP+SV VD+ GTGKIP I ++++E FD RP I LDL + Sbjct: 297 ERCEVQVAYAIGVAEPVSVMVDTAGTGKIPSARIAEIIREVFDLRPRAIIEQLDLLRPIY 356 Query: 998 RFIKTAAYGHFGRDDADFTWE 1060 R KTAAYGHFGR+ +FTWE Sbjct: 357 R--KTAAYGHFGRELPEFTWE 375
>Q38YF8:METK_LACSS S-adenosylmethionine synthetase - Lactobacillus sakei subsp. sakei| (strain 23K) Length = 399 Score = 325 bits (833), Expect = 3e-88 Identities = 180/393 (45%), Positives = 236/393 (60%), Gaps = 61/393 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E LFTSESV+EGHPDK+ DQ+SDA+LDA L QD ++VACET T +V+V+GEI+T A Sbjct: 3 ERHLFTSESVSEGHPDKIADQISDAILDAMLEQDPQARVACETTVTTGLVLVVGEISTTA 62 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE---- 445 VD +K+VR+T + IG+ G D D C V+V +++QSPDIAQGV R ++ Sbjct: 63 YVDIQKVVRETIKKIGYRDGQYGFDGDNCAVIVALDEQSPDIAQGVDDSLESREKDEDPL 122 Query: 446 --VGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK------------------ 553 +GAGDQG+MFG+A D+TPELMPL SH L K+ K Sbjct: 123 DKIGAGDQGLMFGFAVDQTPELMPLPIALSHRLMRKVAELRKSGQLAYLRPDAKAQVTVE 182 Query: 554 ---------------------------------EHVIKPVIPAKYLDENTIFHLNPSGRF 634 E VIK VIPA+YLD+ T + +NP+GRF Sbjct: 183 YDENEQPKRVDTVVISTQHDEDVTLETIQKDMLEQVIKTVIPAEYLDDKTKYFINPTGRF 242 Query: 635 VIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGL 814 VIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I+A+GL Sbjct: 243 VIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGL 302 Query: 815 ARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGG 994 AR+C VQ++YAIGV +P+SV V+++ TG + + I ++ENFD RP I LDL++ Sbjct: 303 ARKCEVQLAYAIGVAQPVSVSVNTFETGTVSEEAIQTAIRENFDLRPAGIIKMLDLQR-- 360 Query: 995 NRFIKTAAYGHFGRDDADFTWEVVKPLKFDKAS 1093 + +TAAYGHFGR D D +WE + + KAS Sbjct: 361 PIYKQTAAYGHFGRTDVDLSWERLDKVDALKAS 393
>Q3SFY2:METK_THIDA S-adenosylmethionine synthetase - Thiobacillus denitrificans (strain| ATCC 25259) Length = 388 Score = 325 bits (832), Expect = 4e-88 Identities = 180/385 (46%), Positives = 238/385 (61%), Gaps = 54/385 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 F+FTSESV+EGHPDK+ DQVSDAVLDA L QD ++VACET+ T + ++ GEITT A + Sbjct: 5 FIFTSESVSEGHPDKMADQVSDAVLDAILTQDKHARVACETLLTTGLCVIAGEITTTAVI 64 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 DY +I R T + IG+ S D+G D + C VLV + +QSPDIAQGV ++ GAGDQ Sbjct: 65 DYNQIARQTIKRIGYDSSDIGFDYNTCSVLVTVGKQSPDIAQGVDRAHDDYLDQ-GAGDQ 123 Query: 464 GIMFGYATDETPELMP----LSH------------------------------------- 520 G+MFGYA +ETP LMP L+H Sbjct: 124 GLMFGYACNETPVLMPMPIHLAHRLTERQSELRKDGRLPWLRPDAKSQVSIRYVDGKPHS 183 Query: 521 ----VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDA 661 VL+T+ L + E +IKPV+P L +T + +NP+GRFV+GGP GDA Sbjct: 184 IDTVVLSTQHDPEVSHAQLSEAVIEEIIKPVLPKDMLSADTRYLVNPTGRFVVGGPMGDA 243 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA +C+VQ+S Sbjct: 244 GLTGRKIIVDTYGGASPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLADKCMVQVS 303 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIGV +P S+ VD++GTGKIP+ +I++L++ +FD RP I LDL + + +TA+Y Sbjct: 304 YAIGVAKPTSLMVDTFGTGKIPEAKIVELIQAHFDLRPKGIVNMLDLLR--PIYTRTASY 361 Query: 1022 GHFGRDDADFTWEVVKPLKFDKASA 1096 GHFGRD+ +FTWEV KA+A Sbjct: 362 GHFGRDEPEFTWEVTDKAAELKAAA 386
>Q6HCB4:METK_BACHK S-adenosylmethionine synthetase - Bacillus thuringiensis subsp.| konkukian Length = 399 Score = 324 bits (831), Expect = 5e-88 Identities = 183/399 (45%), Positives = 238/399 (59%), Gaps = 63/399 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M + LFTSESV EGHPDK+CDQ+SD++LDA L++DA+++VACET T +V+V GEIT Sbjct: 1 MTKKRHLFTSESVTEGHPDKICDQISDSILDAILSKDANARVACETTVTTGLVLVAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD KIVR+T + IG+ G DA+ C VL +I++QS DIA GV R Sbjct: 61 TSTYVDIPKIVRETIQGIGYTRAKYGFDAETCAVLTSIDEQSADIAMGVDQALEAREGQM 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATK------------------- 535 E +GAGDQG+MFG+A +ET ELMPL +H LA + Sbjct: 121 TDAEIEAIGAGDQGLMFGFACNETQELMPLPISLAHKLARRLTEVRKNDTLSYLRPDGKT 180 Query: 536 --------------------------------LGARLKEHVIKPVIPAKYLDENTIFHLN 619 + LKEHVIK V+PA+ +D T F +N Sbjct: 181 QVTVEYDENGKPVRVDTIVISTQHHPDVTWEEIDRDLKEHVIKAVVPAELIDGETKFFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KD TKVDRS AY AR AK+I Sbjct: 241 PTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA + VQ++YAIGV +P+S+ VD++GTGK+ + +++LV+ NFD RP I LD Sbjct: 301 VAAGLAEKAEVQLAYAIGVAQPVSISVDTFGTGKVSEDVLVELVRNNFDLRPAGIIKMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 L++ + +TAAYGHFGR D D TWE + DKA+A Sbjct: 361 LRR--PIYKQTAAYGHFGRTDVDLTWE-----RTDKAAA 392
>Q39W48:METK_GEOMG S-adenosylmethionine synthetase - Geobacter metallireducens (strain| GS-15 / ATCC 53774 / DSM 7210) Length = 389 Score = 324 bits (830), Expect = 7e-88 Identities = 181/381 (47%), Positives = 231/381 (60%), Gaps = 57/381 (14%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M + ++FTSESV+EGHPDK+ DQVSD++LDA LAQD ++VACET+ T M ++ GEIT Sbjct: 1 MEMKDYIFTSESVSEGHPDKVADQVSDSILDAILAQDPRARVACETLVTTGMAVIAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGV---HGHFTKRP 439 T A VDY K+VR+T R IG+ +G D + C VLV+I++QSPDI+QGV G F Sbjct: 61 TSAVVDYPKVVRETIREIGYNDSAMGFDWETCAVLVSIDKQSPDISQGVTEGEGMF---- 116 Query: 440 EEVGAGDQGIMFGYATDETPELMPLS----HVLATKLGARLK------------------ 553 +E GAGDQG+MFGYA ETPELMP+S H L KL K Sbjct: 117 KEQGAGDQGLMFGYACTETPELMPMSITYAHKLTQKLAEVRKNGVLDFLRPDSKSQVSVE 176 Query: 554 --------------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFV 637 E V+K +IPA +DE T +NP+GRFV Sbjct: 177 YVDDKPVRVDTVVISSQHTPEVSYEAIKEGIIEEVVKKIIPAHLMDERTRMLINPTGRFV 236 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 +GGP GD GLTGRKII+D+Y KDP+KVDRS AY+ R AK+++A+GL Sbjct: 237 VGGPMGDCGLTGRKIIVDSYGGHGAHGGGAFSGKDPSKVDRSAAYMGRYVAKNLVAAGLC 296 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 +C VQ++YAIGV EP+SV VD+ GTGKI + I ++V+E FD RP I LDL + Sbjct: 297 EKCEVQVAYAIGVAEPVSVMVDTAGTGKISSKRIAEIVREVFDLRPRAIIEQLDLLRPIY 356 Query: 998 RFIKTAAYGHFGRDDADFTWE 1060 R KTAAYGHFGR+ +FTWE Sbjct: 357 R--KTAAYGHFGRELPEFTWE 375
>Q67T90:METK_SYMTH S-adenosylmethionine synthetase - Symbiobacterium thermophilum| Length = 398 Score = 323 bits (829), Expect = 9e-88 Identities = 178/379 (46%), Positives = 226/379 (59%), Gaps = 60/379 (15%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV EGHPDK+ DQ+SDAVLDA LA D ++VACET+ T +V+V GEITT A V Sbjct: 8 YLFTSESVTEGHPDKMADQISDAVLDAILALDPRARVACETLLTTGLVVVTGEITTHAYV 67 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGV------HGHFTKRPEE 445 D +VRD R+IG+ G D C V+ I+ QSPDIAQGV G ++ E Sbjct: 68 DIPNLVRDVVRDIGYTRAKYGFDGSTCGVMTAIDPQSPDIAQGVDVAIEVRGEVNEKELE 127 Query: 446 VGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK-------------------- 553 +GAGDQG+MFG+A DETPELMPL +H LA +L K Sbjct: 128 IGAGDQGMMFGFACDETPELMPLPISLAHRLARRLAQVRKNGTLPYLRPDGKTQVTIEYE 187 Query: 554 ------------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 ++VI V+ +D+ T + +NP+GRFV+G Sbjct: 188 DGRPKRIDTIVISAQHDPDTTQEQIRKDVIDYVILDVVDRNLIDDRTRYFINPTGRFVVG 247 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GP GD GLTGRKII+DTY KDPTKVDRSGAY AR AK+I+A+GLAR+ Sbjct: 248 GPQGDTGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSGAYAARWVAKNIVAAGLARK 307 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRF 1003 C VQ++YAIGV P+S+ V ++GTGK+PD + +LV+E FD RPG I +LDL++ R Sbjct: 308 CEVQVAYAIGVAHPVSILVTTFGTGKLPDERLAQLVRETFDLRPGAIIRDLDLRRPIYR- 366 Query: 1004 IKTAAYGHFGRDDADFTWE 1060 + AAYGHFGR D D WE Sbjct: 367 -QVAAYGHFGRPDLDLPWE 384
>Q5KW02:METK_GEOKA S-adenosylmethionine synthetase - Geobacillus kaustophilus| Length = 403 Score = 323 bits (829), Expect = 9e-88 Identities = 179/387 (46%), Positives = 233/387 (60%), Gaps = 63/387 (16%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+A+ LFTSESV EGHPDK+CDQ+SDA+LDA L +D +++VACET T +V+V GEIT Sbjct: 1 MSAKRRLFTSESVTEGHPDKICDQISDAILDAILEKDPNARVACETSVTTGLVLVSGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGV-------HGHF 427 T VD +IVRDT R IG+ G DAD C VL +I++QSPDIA GV G Sbjct: 61 TSTYVDIPRIVRDTVREIGYTRAKYGFDADTCAVLTSIDEQSPDIAMGVDRALEAREGQM 120 Query: 428 TKRP-EEVGAGDQGIMFGYATDET----PELMPLSH------------------------ 520 T E +GAGDQG+MFG+A +ET P + L+H Sbjct: 121 TDEEIEAIGAGDQGLMFGFACNETEELMPMPISLAHRLARRLAEVRKTDVLPYLRPDGKT 180 Query: 521 ---------------------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLN 619 + ++ +KE VIKPV+PA+ LDENT + +N Sbjct: 181 QVTIEYDENGKPVRVDTIVVSAQHHPEITQEQIQRDIKEQVIKPVVPAELLDENTKYFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I Sbjct: 241 PTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA +C VQ++YAIGV P+S+ +D++GTGK+ + ++++V+ NFD RP I LD Sbjct: 301 VAAGLADKCEVQLAYAIGVARPVSISIDTFGTGKVSEDILIEVVRNNFDLRPAGIIKMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWE 1060 L++ + +TAAYGHFGR D D WE Sbjct: 361 LRR--PIYKQTAAYGHFGRTDIDLPWE 385
>Q2IM98:METK_ANADE S-adenosylmethionine synthetase - Anaeromyxobacter dehalogenans| (strain 2CP-C) Length = 390 Score = 323 bits (828), Expect = 1e-87 Identities = 179/377 (47%), Positives = 226/377 (59%), Gaps = 53/377 (14%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M + FLFTSESV EGHPDK+ DQ+SDAVLDA L QD +VACET+ KT VM+ GEIT Sbjct: 1 MPLQDFLFTSESVTEGHPDKMADQISDAVLDAVLRQDPKGRVACETLLKTGYVMIAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV 448 TKA +DY K+ R+T R IG+ S D+G DA+ C VLV ++QQSPDI QGV + Sbjct: 61 TKARIDYPKLARETVRRIGYTSGDMGFDANTCAVLVAVDQQSPDIGQGV--------DTG 112 Query: 449 GAGDQGIMFGYATDETPELMP----LSHVLATKLG------------------------- 541 GAGDQG+MFGYA DETPELMP +H + +L Sbjct: 113 GAGDQGMMFGYACDETPELMPAPIQYAHAVTKQLAKARRAGLDLLRPDGKSQVSVEYRDG 172 Query: 542 --ARL----------------------KEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGP 649 AR+ +E VI +P + +D T +NP+GRFVIGGP Sbjct: 173 RPARIDTVVVSTQHAESVSNKRLHEAVREQVIAKALPKRLVDRKTRILINPTGRFVIGGP 232 Query: 650 HGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCI 829 GD G+TGRKII+DTY KDP+KVDRS AY+ R AK+++A+GLA RC Sbjct: 233 MGDTGVTGRKIIVDTYGGMGRHGGGAFSGKDPSKVDRSAAYMGRYIAKNVVAAGLAARCE 292 Query: 830 VQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIK 1009 VQ++YAIGV EP+SV VD++GT K+P+ +I + V+E F P I LDL + + K Sbjct: 293 VQVAYAIGVAEPVSVMVDTFGTAKVPEGKIARAVREVFGLTPRAIIEGLDLLR--PVYEK 350 Query: 1010 TAAYGHFGRDDADFTWE 1060 TAAYGHFGR + FTWE Sbjct: 351 TAAYGHFGRTEKTFTWE 367
>Q7URU7:METK_RHOBA S-adenosylmethionine synthetase - Rhodopirellula baltica| Length = 395 Score = 323 bits (827), Expect = 1e-87 Identities = 182/386 (47%), Positives = 241/386 (62%), Gaps = 55/386 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 FLFTSESV+ GHPDKL D++SD++LDA LAQD S+VACET+ T + ++ GEI++KA V Sbjct: 8 FLFTSESVSMGHPDKLADRISDSILDALLAQDPHSRVACETLVTTGLAVIAGEISSKADV 67 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 DYEKIVRDT +G+ D+G+D C+V + ++ QSPDIAQGV+ +++GAGDQ Sbjct: 68 DYEKIVRDTIVAVGYDDPDIGIDGKTCEVQIRLDAQSPDIAQGVNSDEASG-KDIGAGDQ 126 Query: 464 GIMFGYATDETPELMP----LSH------------------------------------- 520 G+MFGYA +TPELMP LSH Sbjct: 127 GLMFGYACKDTPELMPLPIALSHRIINRITEARFNKEVDWLRPDNKSQVTVEYDGNRPVR 186 Query: 521 ----VLATKLGARLK---------EHVIKPVIPAKYLDENTI-FHLNPSGRFVIGGPHGD 658 V++ + G + E+V+KP IPA+ LD+ I +H+NP+G+F+IGGPHGD Sbjct: 187 IEAVVVSAQHGPDVSHDEIEKFVIENVVKPSIPAE-LDKGDIKYHINPTGKFIIGGPHGD 245 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 GLTGRKII+DTY KD TKVDRS AY+AR AK+I+A+GLA RC VQ+ Sbjct: 246 CGLTGRKIIVDTYGGWGRHGGGAFSGKDSTKVDRSAAYMARYVAKNIVAAGLAERCEVQL 305 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAA 1018 +YAIGV EP+SV VD+ GTGKI D ++ +L++E+F PG I +L L++ F++T A Sbjct: 306 AYAIGVTEPVSVHVDTEGTGKIEDAKLCELIREHFPLTPGGIIDHLQLRR--PVFVETTA 363 Query: 1019 YGHFGRDDADFTWEVVKPLKFDKASA 1096 GHFGRD FTWE K DKA A Sbjct: 364 GGHFGRDGEGFTWE-----KTDKADA 384
>Q5FIN8:METK_LACAC S-adenosylmethionine synthetase - Lactobacillus acidophilus| Length = 399 Score = 323 bits (827), Expect = 1e-87 Identities = 184/396 (46%), Positives = 232/396 (58%), Gaps = 63/396 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E LFTSESV+EGHPDK+ DQ+SDA+LDA L +D +S VACET+ T MV V GEI+T A Sbjct: 2 EKRLFTSESVSEGHPDKVADQISDAILDAMLKKDPNSHVACETIVTTGMVFVFGEISTSA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP------ 439 VD + +VR T IG+ ++G D + C V+V+I++QSPDIA GV R Sbjct: 62 YVDIQDVVRKTILKIGYDRPELGFDGNNCAVMVDIDEQSPDIADGVDHSLETRENKSDND 121 Query: 440 --EEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLKEH-------------- 559 +++GAGDQG+MFG+A ETPELMPL SH L ++ + K+H Sbjct: 122 ELDQIGAGDQGLMFGFAIKETPELMPLPISLSHRLMRRVASLRKDHTLEWLRPDAKAQVT 181 Query: 560 -------------------------------------VIKPVIPAKYLDENTIFHLNPSG 628 VIK VIPAKYLDENT F +NPSG Sbjct: 182 VEYDENGKPLCVDTVVISTQTDAEVSNEEICRAMIDLVIKEVIPAKYLDENTKFLINPSG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFVIGGP GD+GLTGRKII+DTY KDPTKVDRS +Y AR AK+I+A+ Sbjct: 242 RFVIGGPKGDSGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSASYAARYVAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLA RC VQ++YAIGV P+S+ +D+ GTG + D + + V+ FD RP I LDL++ Sbjct: 302 GLAYRCEVQLAYAIGVAHPVSIMIDTAGTGTVDDELLTEAVRNVFDLRPAGIIKMLDLRR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 + +TAAYGHFGR D D WE K DK A Sbjct: 362 --PIYEQTAAYGHFGRTDVDLPWE-----KTDKTQA 390
>Q632S5:METK_BACCZ S-adenosylmethionine synthetase - Bacillus cereus (strain ZK / E33L)| Length = 399 Score = 323 bits (827), Expect = 1e-87 Identities = 182/399 (45%), Positives = 238/399 (59%), Gaps = 63/399 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M + LFTSESV EGHPDK+CDQ+SD++LDA L++DA+++VACET T +V+V GEIT Sbjct: 1 MTKKRHLFTSESVTEGHPDKICDQISDSILDAILSKDANARVACETTVTTGLVLVAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD KIVR+T + IG+ G DA+ C VL +I++QS DIA GV R Sbjct: 61 TSTYVDIPKIVRETIQGIGYTRAKYGFDAETCAVLTSIDEQSADIAMGVDQALEAREGQM 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATK------------------- 535 E +GAGDQG+MFG+A +ET ELMPL +H LA + Sbjct: 121 TDAEIEAIGAGDQGLMFGFACNETQELMPLPISLAHKLARRLTEVRKNDTLSYLRPDGKT 180 Query: 536 --------------------------------LGARLKEHVIKPVIPAKYLDENTIFHLN 619 + LKEHVIK V+PA+ +D T F +N Sbjct: 181 QVTVEYDENGKPVRVDTIVISTQHHPDVTWEEIDRDLKEHVIKAVVPAELIDGETKFFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KD TKVDRS AY AR AK+I Sbjct: 241 PTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA + VQ++YAIGV +P+S+ VD++GTGK+ + +++LV+ NFD RP I LD Sbjct: 301 VAAGLAEKAEVQLAYAIGVAQPVSISVDTFGTGKVSEDVLVELVRNNFDLRPAGIIKMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 L++ + +TAAYGHFGR D D +WE + DKA+A Sbjct: 361 LRR--PIYKQTAAYGHFGRTDVDLSWE-----RTDKAAA 392
>Q816Q8:METK_BACCR S-adenosylmethionine synthetase - Bacillus cereus (strain ATCC 14579| / DSM 31) Length = 399 Score = 323 bits (827), Expect = 1e-87 Identities = 182/399 (45%), Positives = 238/399 (59%), Gaps = 63/399 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M + LFTSESV EGHPDK+CDQ+SD++LDA L++DA+++VACET T +V+V GEIT Sbjct: 1 MTKKRHLFTSESVTEGHPDKICDQISDSILDAILSKDANARVACETTVTTGLVLVAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD KIVR+T + IG+ G DA+ C VL +I++QS DIA GV R Sbjct: 61 TSTYVDIPKIVRETIQGIGYTRAKYGFDAETCAVLTSIDEQSADIAMGVDQALEAREGQM 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATK------------------- 535 E +GAGDQG+MFG+A +ET ELMPL +H LA + Sbjct: 121 TDAEIEAIGAGDQGLMFGFACNETQELMPLPISLAHKLARRLTEVRKDDTLSYLRPDGKT 180 Query: 536 --------------------------------LGARLKEHVIKPVIPAKYLDENTIFHLN 619 + LKEHVIK V+PA+ +D T F +N Sbjct: 181 QVTVEYDENGKPVRVDTIVISTQHHPDVTWEEIDRDLKEHVIKAVVPAELMDGETKFFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KD TKVDRS AY AR AK+I Sbjct: 241 PTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA + VQ++YAIGV +P+S+ VD++GTGK+ + +++LV+ NFD RP I LD Sbjct: 301 VAAGLAEKAEVQLAYAIGVAQPVSISVDTFGTGKVSEDVLVELVRNNFDLRPAGIIKMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 L++ + +TAAYGHFGR D D +WE + DKA+A Sbjct: 361 LRR--PIYKQTAAYGHFGRTDVDLSWE-----RTDKAAA 392
>Q72YV6:METK_BACC1 S-adenosylmethionine synthetase - Bacillus cereus (strain ATCC 10987)| Length = 399 Score = 323 bits (827), Expect = 1e-87 Identities = 182/399 (45%), Positives = 238/399 (59%), Gaps = 63/399 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M + LFTSESV EGHPDK+CDQ+SD++LDA L++DA+++VACET T +V+V GEIT Sbjct: 1 MTKKRHLFTSESVTEGHPDKICDQISDSILDAILSKDANARVACETTVTTGLVLVAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD KIVR+T + IG+ G DA+ C VL +I++QS DIA GV R Sbjct: 61 TSTYVDIPKIVRETIQGIGYTRAKYGFDAETCAVLTSIDEQSADIAMGVDQALEAREGQM 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATK------------------- 535 E +GAGDQG+MFG+A +ET ELMPL +H LA + Sbjct: 121 TDAEIEAIGAGDQGLMFGFACNETQELMPLPISLAHKLARRLTEVRKDDTLSYLRPDGKT 180 Query: 536 --------------------------------LGARLKEHVIKPVIPAKYLDENTIFHLN 619 + LKEHVIK V+PA+ +D T F +N Sbjct: 181 QVTVEYDENGKPVRVDTIVISTQHHPDVTWEEIDRDLKEHVIKAVVPAELIDGETKFFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KD TKVDRS AY AR AK+I Sbjct: 241 PTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA + VQ++YAIGV +P+S+ VD++GTGK+ + +++LV+ NFD RP I LD Sbjct: 301 VAAGLAEKAEVQLAYAIGVAQPVSISVDTFGTGKVSEDVLVELVRNNFDLRPAGIIKMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 L++ + +TAAYGHFGR D D +WE + DKA+A Sbjct: 361 LRR--PIYKQTAAYGHFGRTDVDLSWE-----RTDKAAA 392
>Q81KI0:METK_BACAN S-adenosylmethionine synthetase - Bacillus anthracis| Length = 399 Score = 323 bits (827), Expect = 1e-87 Identities = 182/399 (45%), Positives = 238/399 (59%), Gaps = 63/399 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M + LFTSESV EGHPDK+CDQ+SD++LDA L++DA+++VACET T +V+V GEIT Sbjct: 1 MTKKRHLFTSESVTEGHPDKICDQISDSILDAILSKDANARVACETTVTTGLVLVAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD KIVR+T + IG+ G DA+ C VL +I++QS DIA GV R Sbjct: 61 TSTYVDIPKIVRETIQGIGYTRAKYGFDAETCAVLTSIDEQSADIAMGVDQALEAREGQM 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATK------------------- 535 E +GAGDQG+MFG+A +ET ELMPL +H LA + Sbjct: 121 TDAEIEAIGAGDQGLMFGFACNETQELMPLPISLAHKLARRLTEVRKNDTLSYLRPDGKT 180 Query: 536 --------------------------------LGARLKEHVIKPVIPAKYLDENTIFHLN 619 + LKEHVIK V+PA+ +D T F +N Sbjct: 181 QVTVEYDENGKPVRVDTIVISTQHHPDVTWEEIDRDLKEHVIKAVVPAELIDGETKFFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KD TKVDRS AY AR AK+I Sbjct: 241 PTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA + VQ++YAIGV +P+S+ VD++GTGK+ + +++LV+ NFD RP I LD Sbjct: 301 VAAGLAEKAEVQLAYAIGVAQPVSISVDTFGTGKVSEDVLVELVRNNFDLRPAGIIKMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 L++ + +TAAYGHFGR D D +WE + DKA+A Sbjct: 361 LRR--PIYKQTAAYGHFGRTDVDLSWE-----RTDKAAA 392
>Q8CXS7:METK_LEPIN S-adenosylmethionine synthetase - Leptospira interrogans| Length = 386 Score = 322 bits (824), Expect = 3e-87 Identities = 181/393 (46%), Positives = 240/393 (61%), Gaps = 57/393 (14%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ + F+FTSESV EGHPDK+CDQ+SDAVLDA L QD S+VACET+ TN+V++ GEIT Sbjct: 1 MSLKDFIFTSESVGEGHPDKVCDQISDAVLDAYLEQDPKSRVACETLVTTNLVVIAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGV---HGHFTKRP 439 +K VD ++I R+ R+IG+ +G DAD V ++ QSPDI+QGV G F Sbjct: 61 SKGKVDAQEIARNVIRDIGYNDITMGFDADFAVVSAHVHAQSPDISQGVTEGEGLF---- 116 Query: 440 EEVGAGDQGIMFGYATDETPELMPL---------SHVLATKLGARLK------------- 553 +E GAGDQG+MFG+A +ETPELMP+ H+ + G +LK Sbjct: 117 KEQGAGDQGLMFGFAINETPELMPMPIYYSHELVKHLAGLRHGNKLKFLRPDAKSQVTVE 176 Query: 554 --------------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFV 637 E IK VIPA L+ NT + +NP+G+F+ Sbjct: 177 YKDGKPVRIDTVVISTQHSPDVTHKQIEEALIEECIKKVIPANLLN-NTKYFINPTGQFI 235 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 IGGPHGDAGLTGRKII+DTY KDP+KVDRS AY+ R AK+++ASGLA Sbjct: 236 IGGPHGDAGLTGRKIIVDTYGGYGRHGGGAFSGKDPSKVDRSAAYMGRYIAKNVVASGLA 295 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 +C VQ++YAIGV EP+SV VD++GTGKI + E++K ++ NF P I +L L + G Sbjct: 296 DKCEVQLAYAIGVAEPVSVHVDTFGTGKISEEELVKRIRANFKLTPRGIIESLKLLEKGR 355 Query: 998 RFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 ++ +TA+YGHFGR + FTWE + DKASA Sbjct: 356 KYRETASYGHFGRKGSTFTWE-----ETDKASA 383
>Q72SM5:METK_LEPIC S-adenosylmethionine synthetase - Leptospira interrogans serogroup| Icterohaemorrhagiae serovar copenhageni Length = 386 Score = 322 bits (824), Expect = 3e-87 Identities = 181/393 (46%), Positives = 240/393 (61%), Gaps = 57/393 (14%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ + F+FTSESV EGHPDK+CDQ+SDAVLDA L QD S+VACET+ TN+V++ GEIT Sbjct: 1 MSLKDFIFTSESVGEGHPDKVCDQISDAVLDAYLEQDPKSRVACETLVTTNLVVIAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGV---HGHFTKRP 439 +K VD ++I R+ R+IG+ +G DAD V ++ QSPDI+QGV G F Sbjct: 61 SKGKVDAQEIARNVIRDIGYNDITMGFDADFAVVSAHVHAQSPDISQGVTEGEGLF---- 116 Query: 440 EEVGAGDQGIMFGYATDETPELMPL---------SHVLATKLGARLK------------- 553 +E GAGDQG+MFG+A +ETPELMP+ H+ + G +LK Sbjct: 117 KEQGAGDQGLMFGFAINETPELMPMPIYYSHELVKHLAGLRHGNKLKFLRPDAKSQVTVE 176 Query: 554 --------------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFV 637 E IK VIPA L+ NT + +NP+G+F+ Sbjct: 177 YKDGKPVRIDTVVISTQHSPDVTHKQIEEALIEECIKKVIPANLLN-NTKYFINPTGQFI 235 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 IGGPHGDAGLTGRKII+DTY KDP+KVDRS AY+ R AK+++ASGLA Sbjct: 236 IGGPHGDAGLTGRKIIVDTYGGYGRHGGGAFSGKDPSKVDRSAAYMGRYIAKNVVASGLA 295 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 +C VQ++YAIGV EP+SV VD++GTGKI + E++K ++ NF P I +L L + G Sbjct: 296 DKCEVQLAYAIGVAEPVSVHVDTFGTGKISEEELVKRIRANFKLTPRGIIESLKLLEKGR 355 Query: 998 RFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 ++ +TA+YGHFGR + FTWE + DKASA Sbjct: 356 KYRETASYGHFGRKGSTFTWE-----ETDKASA 383
>Q92AZ5:METK_LISIN S-adenosylmethionine synthetase - Listeria innocua| Length = 399 Score = 320 bits (821), Expect = 7e-87 Identities = 184/399 (46%), Positives = 232/399 (58%), Gaps = 63/399 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MA LFTSESV++GHPDK+ DQ+SDA+LDA +++D D++VACET T +V+V GEIT Sbjct: 1 MAKNRHLFTSESVSDGHPDKIADQISDAILDAIISKDPDARVACETTVTTGLVLVAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD KIVRDT + IG+ G DA+ C VL I++QSPDIAQGV R Sbjct: 61 TSVYVDIPKIVRDTIKEIGYTRAKYGFDAETCAVLTAIDEQSPDIAQGVDEALESRSGSE 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATK------------------- 535 E +GAGDQG+MFG+ATDET ELMPL +H LA K Sbjct: 121 IDAAIEAIGAGDQGLMFGFATDETEELMPLPIFLAHGLARKLTELRKTNKLDYLRPDAKT 180 Query: 536 --------------------------------LGARLKEHVIKPVIPAKYLDENTIFHLN 619 + L H+ VI A +LDENT + +N Sbjct: 181 QVTVEYDEFNQPVRIDTIVVSTQHHPDITQEQIAKDLHTHLFPEVIDASFLDENTKYFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KDPTKVDRSGAY AR AK+I Sbjct: 241 PTGRFVIGGPLGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSGAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA++ VQ++YAIGV P+S+ +D+YGT ++E++ V E FD RP I LD Sbjct: 301 VAAGLAKKVEVQVAYAIGVARPVSISIDTYGTSDYSEQELIDGVNELFDLRPAGIIHMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 L++ R +TAA+GHFGR D D WE + DKA A Sbjct: 361 LRRPIYR--QTAAFGHFGRSDLDLPWE-----RTDKAEA 392
>Q63YH5:METK_BURPS S-adenosylmethionine synthetase - Burkholderia pseudomallei| (Pseudomonas pseudomallei) Length = 395 Score = 320 bits (819), Expect = 1e-86 Identities = 185/388 (47%), Positives = 235/388 (60%), Gaps = 54/388 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A +LFTSESV+EGHPDK+ DQ+SDA+LDA LAQD S+VA ET+ T +V++ GEITT Sbjct: 2 ANDYLFTSESVSEGHPDKVADQISDAILDAILAQDKYSRVAAETLCNTGLVVLAGEITTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A +DY +I RDT + IG+ + D G+D C VLV ++QSPDIAQGV ++ GA Sbjct: 62 ANIDYIQIARDTIKRIGYDNTDYGIDYRGCAVLVAYDKQSPDIAQGVDRAHDNNLDQ-GA 120 Query: 455 GDQGIMFGYATDETPELMPL----SH---------------------------------- 520 GDQG+MFGYA DETPELMPL SH Sbjct: 121 GDQGLMFGYACDETPELMPLPIHLSHRLVERQANLRRDGRLPWLRPDAKSQVTVRYVDGK 180 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E VIKP +PA + + F +NP+GRFVIGGP Sbjct: 181 PHSIDTVVLSTQHAPEIDLPALREAVIEEVIKPTLPADLIKGDIKFLVNPTGRFVIGGPQ 240 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA R ++ Sbjct: 241 GDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALI 300 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP SV V+++GTG++ D I KLV+E+FD RP I LDL + + KT Sbjct: 301 QVSYAIGVAEPTSVMVNTFGTGRVSDETITKLVREHFDLRPKGIIQMLDLLR--PIYEKT 358 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 AAYGHFGR++ +F+WE DKA A Sbjct: 359 AAYGHFGREEPEFSWEAA-----DKALA 381
>Q3JX94:METK_BURP1 S-adenosylmethionine synthetase - Burkholderia pseudomallei (strain| 1710b) Length = 395 Score = 320 bits (819), Expect = 1e-86 Identities = 185/388 (47%), Positives = 235/388 (60%), Gaps = 54/388 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A +LFTSESV+EGHPDK+ DQ+SDA+LDA LAQD S+VA ET+ T +V++ GEITT Sbjct: 2 ANDYLFTSESVSEGHPDKVADQISDAILDAILAQDKYSRVAAETLCNTGLVVLAGEITTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A +DY +I RDT + IG+ + D G+D C VLV ++QSPDIAQGV ++ GA Sbjct: 62 ANIDYIQIARDTIKRIGYDNTDYGIDYRGCAVLVAYDKQSPDIAQGVDRAHDNNLDQ-GA 120 Query: 455 GDQGIMFGYATDETPELMPL----SH---------------------------------- 520 GDQG+MFGYA DETPELMPL SH Sbjct: 121 GDQGLMFGYACDETPELMPLPIHLSHRLVERQANLRRDGRLPWLRPDAKSQVTVRYVDGK 180 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E VIKP +PA + + F +NP+GRFVIGGP Sbjct: 181 PHSIDTVVLSTQHAPEIDLPALREAVIEEVIKPTLPADLIKGDIKFLVNPTGRFVIGGPQ 240 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA R ++ Sbjct: 241 GDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALI 300 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP SV V+++GTG++ D I KLV+E+FD RP I LDL + + KT Sbjct: 301 QVSYAIGVAEPTSVMVNTFGTGRVSDETITKLVREHFDLRPKGIIQMLDLLR--PIYEKT 358 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 AAYGHFGR++ +F+WE DKA A Sbjct: 359 AAYGHFGREEPEFSWEAA-----DKALA 381
>Q62EZ1:METK_BURMA S-adenosylmethionine synthetase - Burkholderia mallei (Pseudomonas| mallei) Length = 395 Score = 320 bits (819), Expect = 1e-86 Identities = 185/388 (47%), Positives = 235/388 (60%), Gaps = 54/388 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A +LFTSESV+EGHPDK+ DQ+SDA+LDA LAQD S+VA ET+ T +V++ GEITT Sbjct: 2 ANDYLFTSESVSEGHPDKVADQISDAILDAILAQDKYSRVAAETLCNTGLVVLAGEITTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A +DY +I RDT + IG+ + D G+D C VLV ++QSPDIAQGV ++ GA Sbjct: 62 ANIDYIQIARDTIKRIGYDNTDYGIDYRGCAVLVAYDKQSPDIAQGVDRAHDNNLDQ-GA 120 Query: 455 GDQGIMFGYATDETPELMPL----SH---------------------------------- 520 GDQG+MFGYA DETPELMPL SH Sbjct: 121 GDQGLMFGYACDETPELMPLPIHLSHRLVERQANLRRDGRLPWLRPDAKSQVTVRYVDGK 180 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E VIKP +PA + + F +NP+GRFVIGGP Sbjct: 181 PHSIDTVVLSTQHAPEIDLPALREAVIEEVIKPTLPADLIKGDIKFLVNPTGRFVIGGPQ 240 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA R ++ Sbjct: 241 GDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALI 300 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP SV V+++GTG++ D I KLV+E+FD RP I LDL + + KT Sbjct: 301 QVSYAIGVAEPTSVMVNTFGTGRVSDETITKLVREHFDLRPKGIIQMLDLLR--PIYEKT 358 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 AAYGHFGR++ +F+WE DKA A Sbjct: 359 AAYGHFGREEPEFSWEAA-----DKALA 381
>Q5GW76:METK_XANOR S-adenosylmethionine synthetase - Xanthomonas oryzae pv. oryzae| Length = 403 Score = 319 bits (818), Expect = 2e-86 Identities = 180/375 (48%), Positives = 230/375 (61%), Gaps = 56/375 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLDA LAQD ++VACET+ KT + +V GE+TT A Sbjct: 3 SYLFTSESVSEGHPDKIADQISDAVLDAILAQDKRARVACETMVKTGVAIVAGEVTTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 +D E + R +IG+ S DVG D + C VL I +QSPDI QGV K PE+ GAGD Sbjct: 63 IDLEALTRKVILDIGYNSSDVGFDGETCGVLNLIGKQSPDINQGVD---RKNPEQQGAGD 119 Query: 461 QGIMFGYATDETPELMP----LSHVL---------------------------------- 526 QG+MFGYAT+ET MP LSH L Sbjct: 120 QGLMFGYATNETDSFMPAAIHLSHRLVEQQAKIRKKKNSALSWLRPDAKSQVTLRYEDGV 179 Query: 527 ATKLGA------------------RLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 AT + A ++E ++KPV+PAK+L + T FH+NP+G+FVIGGP Sbjct: 180 ATAIDAVVLSTQHDPGVKQKDLIEAVREEILKPVLPAKWLHKGTKFHINPTGKFVIGGPV 239 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLA RC V Sbjct: 240 GDCGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLADRCEV 299 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ V ++GTGKI D +I KL++++FD RP I LDL + +T Sbjct: 300 QVSYAIGVAEPTSISVTTFGTGKIADEQIEKLIRKHFDLRPFGIIQMLDLIH--PMYQQT 357 Query: 1013 AAYGHFGRDDADFTW 1057 A+YGHFGR DFT+ Sbjct: 358 ASYGHFGRKPKDFTY 372
>Q2NZF1:METK_XANOM S-adenosylmethionine synthetase - Xanthomonas oryzae pv. oryzae| (strain MAFF 311018) Length = 403 Score = 319 bits (818), Expect = 2e-86 Identities = 180/375 (48%), Positives = 230/375 (61%), Gaps = 56/375 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLDA LAQD ++VACET+ KT + +V GE+TT A Sbjct: 3 SYLFTSESVSEGHPDKIADQISDAVLDAILAQDKRARVACETMVKTGVAIVAGEVTTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 +D E + R +IG+ S DVG D + C VL I +QSPDI QGV K PE+ GAGD Sbjct: 63 IDLEALTRKVILDIGYNSSDVGFDGETCGVLNLIGKQSPDINQGVD---RKNPEQQGAGD 119 Query: 461 QGIMFGYATDETPELMP----LSHVL---------------------------------- 526 QG+MFGYAT+ET MP LSH L Sbjct: 120 QGLMFGYATNETDSFMPAAIHLSHRLVEQQAKIRKKKNSALSWLRPDAKSQVTLRYEDGV 179 Query: 527 ATKLGA------------------RLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 AT + A ++E ++KPV+PAK+L + T FH+NP+G+FVIGGP Sbjct: 180 ATAIDAVVLSTQHDPGVKQKDLIEAVREEILKPVLPAKWLHKGTKFHINPTGKFVIGGPV 239 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLA RC V Sbjct: 240 GDCGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLADRCEV 299 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ V ++GTGKI D +I KL++++FD RP I LDL + +T Sbjct: 300 QVSYAIGVAEPTSISVTTFGTGKIADEQIEKLIRKHFDLRPFGIIQMLDLIH--PMYQQT 357 Query: 1013 AAYGHFGRDDADFTW 1057 A+YGHFGR DFT+ Sbjct: 358 ASYGHFGRKPKDFTY 372
>Q3BXB7:METK_XANC5 S-adenosylmethionine synthetase - Xanthomonas campestris pv.| vesicatoria (strain 85-10) Length = 403 Score = 319 bits (818), Expect = 2e-86 Identities = 180/375 (48%), Positives = 230/375 (61%), Gaps = 56/375 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLDA LAQD ++VACET+ KT + +V GE+TT A Sbjct: 3 SYLFTSESVSEGHPDKIADQISDAVLDAILAQDKRARVACETMVKTGVAIVAGEVTTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 +D E + R +IG+ S DVG D + C VL I +QSPDI QGV K PE+ GAGD Sbjct: 63 IDLEALTRKVILDIGYNSSDVGFDGETCGVLNLIGKQSPDINQGVD---RKNPEQQGAGD 119 Query: 461 QGIMFGYATDETPELMP----LSHVL---------------------------------- 526 QG+MFGYAT+ET MP LSH L Sbjct: 120 QGLMFGYATNETDSFMPAAIHLSHRLVEQQAKIRKKKNSALSWLRPDAKSQVTLRYEDGV 179 Query: 527 ATKLGA------------------RLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 AT + A ++E ++KPV+PAK+L + T FH+NP+G+FVIGGP Sbjct: 180 ATAIDAVVLSTQHDPGVKQKDLIEAVREEILKPVLPAKWLHKGTKFHINPTGKFVIGGPV 239 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLA RC V Sbjct: 240 GDCGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLADRCEV 299 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ V ++GTGKI D +I KL++++FD RP I LDL + +T Sbjct: 300 QVSYAIGVAEPTSISVTTFGTGKIADEQIEKLIRKHFDLRPFGIIQMLDLIH--PMYQQT 357 Query: 1013 AAYGHFGRDDADFTW 1057 A+YGHFGR DFT+ Sbjct: 358 ASYGHFGRKPKDFTY 372
>Q8PP75:METK_XANAC S-adenosylmethionine synthetase - Xanthomonas axonopodis pv. citri| Length = 403 Score = 319 bits (818), Expect = 2e-86 Identities = 180/375 (48%), Positives = 230/375 (61%), Gaps = 56/375 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLDA LAQD ++VACET+ KT + +V GE+TT A Sbjct: 3 SYLFTSESVSEGHPDKIADQISDAVLDAILAQDKRARVACETMVKTGVAIVAGEVTTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 +D E + R +IG+ S DVG D + C VL I +QSPDI QGV K PE+ GAGD Sbjct: 63 IDLEALTRKVILDIGYNSSDVGFDGETCGVLNLIGKQSPDINQGVD---RKNPEQQGAGD 119 Query: 461 QGIMFGYATDETPELMP----LSHVL---------------------------------- 526 QG+MFGYAT+ET MP LSH L Sbjct: 120 QGLMFGYATNETDSFMPAAIHLSHRLVEQQAKIRKKKNSALSWLRPDAKSQVTLRYEDGV 179 Query: 527 ATKLGA------------------RLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 AT + A ++E ++KPV+PAK+L + T FH+NP+G+FVIGGP Sbjct: 180 ATAIDAVVLSTQHDPGVKQKDLIEAVREEILKPVLPAKWLHKGTKFHINPTGKFVIGGPV 239 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLA RC V Sbjct: 240 GDCGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLADRCEV 299 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ V ++GTGKI D +I KL++++FD RP I LDL + +T Sbjct: 300 QVSYAIGVAEPTSISVTTFGTGKIADEQIEKLIRKHFDLRPFGIIQMLDLIH--PMYQQT 357 Query: 1013 AAYGHFGRDDADFTW 1057 A+YGHFGR DFT+ Sbjct: 358 ASYGHFGRKPKDFTY 372
>Q5E7R2:METK_VIBF1 S-adenosylmethionine synthetase - Vibrio fischeri (strain ATCC 700601| / ES114) Length = 384 Score = 319 bits (818), Expect = 2e-86 Identities = 180/372 (48%), Positives = 230/372 (61%), Gaps = 54/372 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MVMV GE+TT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEVTTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P+E GAGDQG Sbjct: 65 IEEITRETVREIGYVHSDMGFDANSCAVLNTIGKQSPDINQGVD---KADPKEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL----SHVLATK--------------------------------- 535 IMFGYAT+ETP LMP SH+L K Sbjct: 122 IMFGYATNETPILMPAPITYSHLLVQKQAEVRKSGKLDFLRPDAKSQVTFQYDQGKIVGI 181 Query: 536 -----------------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 L + E +IKPV+PA++L+++T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHCDSVTTPDLREAVMEEIIKPVLPAEWLNKDTNFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+G+A RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGMADRCEIQLSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV +P S+ V+++GT K+ I++ V++NFD RP + L+L + + KTAAYG Sbjct: 302 AIGVADPTSIMVETFGTEKVSHDIIIEAVRQNFDLRPYGLQEMLNLLQ--PIYKKTAAYG 359 Query: 1025 HFGRDDADFTWE 1060 HFGR+ +F WE Sbjct: 360 HFGRE--EFPWE 369
>Q2T267:METK_BURTA S-adenosylmethionine synthetase - Burkholderia thailandensis (strain| E264 / ATCC 700388 / DSM 13276 / CIP 106301) Length = 395 Score = 319 bits (818), Expect = 2e-86 Identities = 184/388 (47%), Positives = 235/388 (60%), Gaps = 54/388 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A +LFTSESV+EGHPDK+ DQ+SDA+LDA LAQD S+VA ET+ T +V++ GEITT Sbjct: 2 ANDYLFTSESVSEGHPDKVADQISDAILDAILAQDKYSRVAAETLCNTGLVVLAGEITTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A +DY +I RDT + IG+ + D G+D C VLV ++QSPDIAQGV ++ GA Sbjct: 62 ANIDYIQIARDTIKRIGYDNTDYGIDYRGCAVLVAYDKQSPDIAQGVDRAHDNNLDQ-GA 120 Query: 455 GDQGIMFGYATDETPELMPL----SH---------------------------------- 520 GDQG+MFGYA DETPELMPL SH Sbjct: 121 GDQGLMFGYACDETPELMPLPIHLSHRLVERQANLRRDGRLPWLRPDAKSQVTVRYVDGK 180 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E +IKP +PA + + F +NP+GRFVIGGP Sbjct: 181 PHSIDTVVLSTQHAPDIDLPALREAVIEEIIKPTLPADLIKGDIKFLVNPTGRFVIGGPQ 240 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA R ++ Sbjct: 241 GDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALI 300 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP SV V+++GTG++ D I KLV+E+FD RP I LDL + + KT Sbjct: 301 QVSYAIGVAEPTSVMVNTFGTGRVSDETITKLVREHFDLRPKGIIQMLDLLR--PIYEKT 358 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 AAYGHFGR++ +F+WE DKA A Sbjct: 359 AAYGHFGREEPEFSWEAA-----DKALA 381
>Q5WDZ8:METK_BACSK S-adenosylmethionine synthetase - Bacillus clausii (strain KSM-K16)| Length = 405 Score = 319 bits (817), Expect = 2e-86 Identities = 180/398 (45%), Positives = 237/398 (59%), Gaps = 63/398 (15%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+CDQ+SDA+LD L +D +++VACET T +V+V GEITT VD Sbjct: 9 LFTSESVTEGHPDKICDQISDAILDEILKKDPNARVACETSVTTGLVLVAGEITTNTYVD 68 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--------E 442 +VR T + IG+ G DA+ C VL +I++QS DIAQGV R E Sbjct: 69 IPSVVRQTIKGIGYTRAKYGFDAETCAVLTSIDEQSADIAQGVDKALEAREGQMTDAEIE 128 Query: 443 EVGAGDQGIMFGYATDETPELMPL----SHVLATKLG----------------------- 541 +GAGDQG+MFG+AT+ET ELMPL SH L+ +L Sbjct: 129 AIGAGDQGLMFGFATNETEELMPLPISLSHKLSRRLTEVRKNGTLGYLRPDGKTQVTIEY 188 Query: 542 ----------------------------ARLKEHVIKPVIPAKYLDENTIFHLNPSGRFV 637 A LKEHVI+ V+P+ +DE T + +NP+GRFV Sbjct: 189 DENDTPVRVDTIVLSTQHAPEVTLEQIQADLKEHVIEAVVPSALIDEETKYFINPTGRFV 248 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 IGGP GDAGLTGRKII+DTY KD TKVDRSGAY AR AK+I+A+GLA Sbjct: 249 IGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSGAYAARYVAKNIVAAGLA 308 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 +C VQ++YAIGV +P+S+ V+++GTGK + +++LV+++FD RP I LDL++ Sbjct: 309 DKCEVQLAYAIGVAQPVSIAVNTFGTGKAAEDVLVELVRKHFDLRPAGIIRMLDLRR--P 366 Query: 998 RFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA*EQDI 1111 + +TAAYGHFGR D WE DKA+A ++D+ Sbjct: 367 IYKQTAAYGHFGRTDVPLPWEAT-----DKAAALKEDV 399
>Q47JN4:METK_DECAR S-adenosylmethionine synthetase - Dechloromonas aromatica (strain| RCB) Length = 387 Score = 318 bits (816), Expect = 3e-86 Identities = 177/385 (45%), Positives = 232/385 (60%), Gaps = 54/385 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV EGHPDK+ DQ+SDA+LDA LAQD S+VA ET+ T +V++ GEITT A V Sbjct: 4 YLFTSESVGEGHPDKVADQISDAILDAILAQDKHSRVAAETLCNTGLVVLAGEITTNANV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 DY ++ RDT + IG+ + + G+D C VLV ++QSPDIAQGV+ + + GAGDQ Sbjct: 64 DYIQVARDTIKRIGYDNTEYGIDYKGCAVLVAYDKQSPDIAQGVNAAYDDNLGQ-GAGDQ 122 Query: 464 GIMFGYATDETPELMPL----SH------------------------------------- 520 G+MFGYA DETP LMPL SH Sbjct: 123 GLMFGYACDETPSLMPLPIYLSHRMVERQAMLRKDGRLPWARPDAKSQVTIRYVDGKPHS 182 Query: 521 ----VLATKLGARLK---------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDA 661 VL+T+ + E +IKPV+P + + + + +NP+GRFV+GGP GD Sbjct: 183 IDTVVLSTQHSPDISLEDLREATIEQIIKPVLPKELIKGDIKYLVNPTGRFVVGGPQGDC 242 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA RC+VQ+S Sbjct: 243 GLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYATRYVAKNIVAAGLASRCLVQVS 302 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIGV EP S+ V++YGTGK+ + + LV+++FD RP I LDL + + KTAAY Sbjct: 303 YAIGVAEPTSIMVETYGTGKVSNETLTALVRKHFDLRPKGIVNMLDLLR--PIYQKTAAY 360 Query: 1022 GHFGRDDADFTWEVVKPLKFDKASA 1096 GHFGRD+ +FTWE K+ A Sbjct: 361 GHFGRDEPEFTWEATDRANLLKSDA 385
>Q2Y5Z1:METK_NITMU S-adenosylmethionine synthetase - Nitrosospira multiformis (strain| ATCC 25196 / NCIMB 11849) Length = 399 Score = 318 bits (814), Expect = 5e-86 Identities = 172/374 (45%), Positives = 232/374 (62%), Gaps = 55/374 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQ+SD++LDA LAQD +++VACET+ T ++++ GEITT+A V Sbjct: 4 YLFTSESVSEGHPDKVADQISDSILDAILAQDPNARVACETLCSTGLIVMSGEITTQANV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPE-EVGAGD 460 DY ++ R + IG+ S D+G D + C VL +QSPDIA+GV+ TK E + GAGD Sbjct: 64 DYMQVARAAVKRIGYNSSDIGFDYNTCAVLTAFNKQSPDIARGVNR--TKEEEMDQGAGD 121 Query: 461 QGIMFGYATDETPEL--MPLSH-------------------------------------- 520 QG+MFGYA DETP+L MP+ + Sbjct: 122 QGLMFGYACDETPQLMPMPIYYAHRLMERQAELRKDGRLPWLRPDAKSQVSVRYLDGKPQ 181 Query: 521 --------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGD 658 + T L + E VIKPV+P K L T + +NP+GRFV+GGP GD Sbjct: 182 RIETVVISTQHHPDISHTDLSEAIIEEVIKPVLPKKMLSGETRYLINPTGRFVVGGPMGD 241 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 GLTGRKII+D+Y KDP+KVDRS AY R AK+++A+G+A RC VQ+ Sbjct: 242 CGLTGRKIIVDSYGGTAHHGGGAFSGKDPSKVDRSAAYAGRYVAKNLVAAGIASRCEVQM 301 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAA 1018 +YAIGV P+S+ VD++GTGKIPD +I+KL++ +FD RP I LDL + + KTAA Sbjct: 302 AYAIGVARPVSLMVDTFGTGKIPDDKIVKLIERHFDLRPRGIIHGLDLLR--PIYEKTAA 359 Query: 1019 YGHFGRDDADFTWE 1060 YGHFGRD+ +F+WE Sbjct: 360 YGHFGRDEPEFSWE 373
>Q2RK28:METK_MOOTA S-adenosylmethionine synthetase - Moorella thermoacetica (strain ATCC| 39073) Length = 395 Score = 318 bits (814), Expect = 5e-86 Identities = 174/398 (43%), Positives = 232/398 (58%), Gaps = 61/398 (15%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ D+++DAVLDA A+D ++VACE + T +++V G+ITT VD Sbjct: 5 LFTSESVTEGHPDKIADRIADAVLDAIYAKDNQARVACECLVSTGLILVAGQITTDCYVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 ++ R+T R IG+ G D D C V+ +I++QSPDIA GV+ + K+ E Sbjct: 65 IPRVARETVREIGYTRAKFGFDCDTCAVITSIDEQSPDIAMGVNEAWEKKQGEARDEVET 124 Query: 446 VGAGDQGIMFGYATDETPELMP----LSHVLATKLGARLKEH------------------ 559 +GAGDQG+MFGYAT ETPE MP L+H L +L A KE Sbjct: 125 LGAGDQGMMFGYATSETPEFMPMPIALAHALTRRLAAVRKERILPYLRPDGKSQVTVEYE 184 Query: 560 --------------------------------VIKPVIPAKYLDENTIFHLNPSGRFVIG 643 VIKPVIPA+ LD T + +NP+GRFVIG Sbjct: 185 DGRPVRVDTVVISTQHRPDIDMATLRDEVLETVIKPVIPAEMLDNRTRYFINPTGRFVIG 244 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GP GD GLTGRK+I+DTY KDPTKVDRS AY AR AK+++A+GLA R Sbjct: 245 GPQGDTGLTGRKLIVDTYGGMARHGGGALSGKDPTKVDRSAAYAARYVAKNVVAAGLADR 304 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRF 1003 C VQ++YAIGV P+S+ V+++GTGK+ D +++L++ +FD RPG I +LDL++ + Sbjct: 305 CEVQVAYAIGVARPVSISVETFGTGKVSDDRLVELIRAHFDLRPGAIIRDLDLRRPIYKA 364 Query: 1004 IKTAAYGHFGRDDADFTWEVVKPLKFDKASA*EQDITL 1117 + + YGHFGR D D WE + DK A D L Sbjct: 365 V--SVYGHFGRPDLDLPWE-----RLDKVEALRADAGL 395
>Q65FV8:METK_BACLD S-adenosylmethionine synthetase - Bacillus licheniformis (strain DSM| 13 / ATCC 14580) Length = 400 Score = 317 bits (813), Expect = 6e-86 Identities = 178/403 (44%), Positives = 236/403 (58%), Gaps = 63/403 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ LFTSESV EGHPDK+CDQ+SD++LD L +D +++VACET T +V+V GEIT Sbjct: 1 MSKNRRLFTSESVTEGHPDKICDQISDSILDEILKKDPNARVACETSVTTGLVLVSGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD K VR+T + IG+ G DA+ C VL +I++QSPDIA GV R Sbjct: 61 TSTYVDIPKTVRETIKEIGYTRAKYGFDAETCAVLTSIDEQSPDIAMGVDQALEAREGAM 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMP----LSHVLATK------------------- 535 E +GAGDQG+MFG+A +ET ELMP L+H L+ + Sbjct: 121 SDAEIEAIGAGDQGLMFGFACNETKELMPLPISLAHKLSRRLTEVRKEEILPYLRPDGKT 180 Query: 536 --------------------------------LGARLKEHVIKPVIPAKYLDENTIFHLN 619 + LKEHVI PV+P + +DENT + +N Sbjct: 181 QVTVEYDENNKPIRIDTIVISTQHHPEISLEQIQRNLKEHVINPVVPKELIDENTKYFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KD TKVDRS AY AR AK+I Sbjct: 241 PTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA C VQ++YAIGV +P+S+ +D++GTGK + ++++V++NFD RP I LD Sbjct: 301 VAAGLADSCEVQLAYAIGVAQPVSISIDTFGTGKASEETLIEVVRKNFDLRPAGIIKMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA*EQD 1108 L++ + +TAAYGHFGR D D WE + DKA ++D Sbjct: 361 LRR--PIYKQTAAYGHFGRLDLDLPWE-----RTDKADQLKKD 396
>Q8PCH3:METK_XANCP S-adenosylmethionine synthetase - Xanthomonas campestris pv.| campestris Length = 403 Score = 317 bits (812), Expect = 8e-86 Identities = 180/375 (48%), Positives = 229/375 (61%), Gaps = 56/375 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLDA LAQD ++VACET+ KT + +V GE+TT A Sbjct: 3 SYLFTSESVSEGHPDKIADQISDAVLDAILAQDKRARVACETMVKTGVAIVAGEVTTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 +D E + R +IG+ S DVG D + C VL I +QSPDI QGV K PE+ GAGD Sbjct: 63 IDLEALTRKVILDIGYNSSDVGFDGETCGVLNLIGKQSPDINQGVD---RKNPEQQGAGD 119 Query: 461 QGIMFGYATDETPELMP----LSHVL---------------------------------- 526 QG+MFGYAT+ET MP LSH L Sbjct: 120 QGLMFGYATNETDSYMPAAIHLSHRLVEQQAKIRKKKNSALSWLRPDAKSQVTLRYEDGV 179 Query: 527 ATKLGA------------------RLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 AT + A ++E ++KPV+PAK+L + T FH+NP+G+FVIGGP Sbjct: 180 ATAIDAVVLSTHHDPGVKQKDLIEAVREEILKPVLPAKWLHKGTKFHINPTGKFVIGGPV 239 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLA RC V Sbjct: 240 GDCGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLADRCEV 299 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ V ++GTGKI D I KL++++FD RP I LDL + +T Sbjct: 300 QVSYAIGVAEPTSISVTTFGTGKIADELIEKLIRKHFDLRPFGIIQMLDLIH--PMYQQT 357 Query: 1013 AAYGHFGRDDADFTW 1057 A+YGHFGR DFT+ Sbjct: 358 ASYGHFGRKPKDFTY 372
>Q4UR08:METK_XANC8 S-adenosylmethionine synthetase - Xanthomonas campestris pv.| campestris (strain 8004) Length = 403 Score = 317 bits (812), Expect = 8e-86 Identities = 180/375 (48%), Positives = 229/375 (61%), Gaps = 56/375 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLDA LAQD ++VACET+ KT + +V GE+TT A Sbjct: 3 SYLFTSESVSEGHPDKIADQISDAVLDAILAQDKRARVACETMVKTGVAIVAGEVTTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 +D E + R +IG+ S DVG D + C VL I +QSPDI QGV K PE+ GAGD Sbjct: 63 IDLEALTRKVILDIGYNSSDVGFDGETCGVLNLIGKQSPDINQGVD---RKNPEQQGAGD 119 Query: 461 QGIMFGYATDETPELMP----LSHVL---------------------------------- 526 QG+MFGYAT+ET MP LSH L Sbjct: 120 QGLMFGYATNETDSYMPAAIHLSHRLVEQQAKIRKKKNSALSWLRPDAKSQVTLRYEDGV 179 Query: 527 ATKLGA------------------RLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 AT + A ++E ++KPV+PAK+L + T FH+NP+G+FVIGGP Sbjct: 180 ATAIDAVVLSTQHDPGVKQKDLIEAVREEILKPVLPAKWLHKGTKFHINPTGKFVIGGPV 239 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLA RC V Sbjct: 240 GDCGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLADRCEV 299 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ V ++GTGKI D I KL++++FD RP I LDL + +T Sbjct: 300 QVSYAIGVAEPTSISVTTFGTGKIADELIEKLIRKHFDLRPFGIIQMLDLIH--PMYQQT 357 Query: 1013 AAYGHFGRDDADFTW 1057 A+YGHFGR DFT+ Sbjct: 358 ASYGHFGRKPKDFTY 372
>Q39BZ1:METK_BURS3 S-adenosylmethionine synthetase - Burkholderia sp. (strain 383)| (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) Length = 395 Score = 317 bits (811), Expect = 1e-85 Identities = 183/388 (47%), Positives = 234/388 (60%), Gaps = 54/388 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A +LFTSESV+EGHPDK+ DQ+SDA+LDA L QD S+VA ET+ T +V++ GEITT Sbjct: 2 ANDYLFTSESVSEGHPDKVADQISDAILDAILEQDKYSRVAAETLCNTGLVVLAGEITTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A +DY +I RDT + IG+ + D G+D C VLV ++QSPDIAQGV ++ GA Sbjct: 62 ANIDYIQIARDTIKRIGYDNTDYGIDYKGCAVLVAYDKQSPDIAQGVDRAHDDNLDQ-GA 120 Query: 455 GDQGIMFGYATDETPELMPL----SH---------------------------------- 520 GDQG+MFGYA DETPELMPL SH Sbjct: 121 GDQGLMFGYACDETPELMPLPIYLSHRLVERQASLRRDGRLQWLRPDAKSQVTVRYVDGK 180 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E +IKP +PA + + F +NP+GRFVIGGP Sbjct: 181 PHSIDTVVLSTQHAPDIELPALREAVIEEIIKPTLPADLIKGDIKFLVNPTGRFVIGGPQ 240 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA R ++ Sbjct: 241 GDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALI 300 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP SV V+++GTG++ D I KLV+E+FD RP I LDL + + KT Sbjct: 301 QVSYAIGVAEPTSVMVNTFGTGRVSDAVITKLVREHFDLRPKGIIKMLDLLR--PIYEKT 358 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 AAYGHFGR++ +F+WE DKA A Sbjct: 359 AAYGHFGREEPEFSWEAT-----DKALA 381
>Q71Z03:METK_LISMF S-adenosylmethionine synthetase - Listeria monocytogenes serotype 4b| (strain F2365) Length = 399 Score = 316 bits (810), Expect = 1e-85 Identities = 182/399 (45%), Positives = 232/399 (58%), Gaps = 63/399 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MA LFTSESV++GHPDK+ DQ+SDA+LDA +++D D++VACET T +V+V GEIT Sbjct: 1 MAKNRHLFTSESVSDGHPDKIADQISDAILDAIISKDPDARVACETTVTTGLVLVAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD KIVRDT + IG+ G DA+ C VL I++QSPDIAQGV R Sbjct: 61 TSVYVDIPKIVRDTIKEIGYTRAKYGFDAETCAVLTAIDEQSPDIAQGVDEALESRSGKE 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATK------------------- 535 E +GAGDQG+MFG+ATDET ELMPL +H LA K Sbjct: 121 IDAAIEAIGAGDQGLMFGFATDETEELMPLPIFLAHGLARKLTELRKTNKLDYLRPDAKT 180 Query: 536 --------------------------------LGARLKEHVIKPVIPAKYLDENTIFHLN 619 + L ++ VI A +LDE+T + +N Sbjct: 181 QVTVEYDEFNQPVRIDTIVVSTQHHPDITQEQIAKDLHTYLFPEVIDASFLDEDTKYFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KDPTKVDRSGAY AR AK+I Sbjct: 241 PTGRFVIGGPLGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSGAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA++ VQ++YAIGV P+S+ +D+YGT ++E++ V E FD RP I LD Sbjct: 301 VAAGLAKKVEVQVAYAIGVARPVSISIDTYGTSDYSEQELIDGVNELFDLRPAGIIHMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 L++ R +TAA+GHFGR D D WE + DKA A Sbjct: 361 LRRPIYR--QTAAFGHFGRSDLDLPWE-----RTDKAEA 392
>Q898W7:METK_CLOTE S-adenosylmethionine synthetase - Clostridium tetani| Length = 391 Score = 316 bits (810), Expect = 1e-85 Identities = 172/384 (44%), Positives = 230/384 (59%), Gaps = 60/384 (15%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+CDQ+SDAVLDA L +D + +VACET T MV+V GEITT VD Sbjct: 4 LFTSESVTEGHPDKICDQISDAVLDAILERDPNGRVACETSVTTGMVLVTGEITTNCYVD 63 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP------EEV 448 KIVR+T IG+ G D+D C VL +I +QSPDIA GV + + + Sbjct: 64 IPKIVRNTIEAIGYTRAKYGFDSDTCAVLTSISEQSPDIAMGVDESLESKQGGMDKEDVI 123 Query: 449 GAGDQGIMFGYATDETPELMPLS----HVLATKLGARLK--------------------- 553 GAGDQG+MFGYA +ET E MP++ H L+ +L K Sbjct: 124 GAGDQGMMFGYANNETSEYMPMAISIAHKLSRRLSEVRKNGTLPYLRPDGKTQVTVEYED 183 Query: 554 -----------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGG 646 EHVI V+P ++LDENT +++NP+GRFV+GG Sbjct: 184 NKAIRIDTIVVSTQHGPEVTREQIEKDIFEHVISKVVPVEFLDENTNYYINPTGRFVVGG 243 Query: 647 PHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRC 826 P GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+++A+G+A + Sbjct: 244 PQGDAGLTGRKIIVDTYGGYGRHGGGAFSGKDPTKVDRSAAYAARWVAKNLVAAGVADKL 303 Query: 827 IVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFI 1006 VQ++YAIG+ +P+S+ V+++GTGKI DR+I++++ + FD RP I L+L++ + Sbjct: 304 EVQLAYAIGIAKPVSISVETFGTGKIDDRKIVEIINKVFDLRPSAIIKELNLRR--PIYK 361 Query: 1007 KTAAYGHFGRDDADFTWEVVKPLK 1078 +TAAYGHFGR D + WE + L+ Sbjct: 362 QTAAYGHFGRTDVELPWESLNKLE 385
>Q8EIB4:METK_SHEON S-adenosylmethionine synthetase - Shewanella oneidensis| Length = 383 Score = 316 bits (809), Expect = 2e-85 Identities = 184/391 (47%), Positives = 241/391 (61%), Gaps = 54/391 (13%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA LAQD ++VACET KT MV+V GE+TT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILAQDPKARVACETYVKTGMVLVGGEVTTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E++ R T R IG+I D+G DAD C VL I +QSPDI QGV P+E GAGDQG Sbjct: 65 IEELTRKTVREIGYIHSDMGFDADSCAVLNAIGKQSPDINQGVD---RADPKEQGAGDQG 121 Query: 467 IMFGYATDETPELM--PLSH---------------------------------------- 520 +MFGYA++ET LM P+++ Sbjct: 122 LMFGYASNETDILMPAPITYAHALVKRQSEVRKNGTLPWLRPDAKSQVTFAYEDNKIVGI 181 Query: 521 ---VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 VL+T+ L + E +IKPV+PA++L+++T + +NP+GRFVIGGP GD G Sbjct: 182 DAIVLSTQHSPDIAQADLIEGVMETIIKPVLPAQWLNKDTKYFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GTGK+ + ++KLV+++FD RP ++ L+L + + TAAYG Sbjct: 302 AIGVAEPTSISVETFGTGKVSEEVLIKLVRQHFDLRPYGLTEMLNLAR--PIYQATAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKASA*EQDITL 1117 HFGR ++F WE DKA A D L Sbjct: 360 HFGR--SEFPWEAT-----DKAEALRADAAL 383
>Q3IDQ1:METK_PSEHT S-adenosylmethionine synthetase - Pseudoalteromonas haloplanktis| (strain TAC 125) Length = 383 Score = 315 bits (806), Expect = 4e-85 Identities = 182/384 (47%), Positives = 235/384 (61%), Gaps = 54/384 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD+ ++VACET KT MVMV GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDSHARVACETYVKTGMVMVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R T R+IG+ + D+G DAD C +L I +QSPDI QGV PEE GAGDQG Sbjct: 65 IEEITRKTIRDIGYTNSDMGFDADSCAILNTIGKQSPDINQGVD---RTSPEEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL----SH-------------------------------------- 520 +MFGYA +ET LMP SH Sbjct: 122 LMFGYACNETEVLMPAPITYSHRLVQRQAQVRKSGELNWLRPDAKSQVTFAYENGKPVGI 181 Query: 521 ---VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 VL+T+ L + E +IKPV+PA+ + T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEDISQKDLIEAVMETIIKPVLPAELITSATKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA +C +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADKCELQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIG+ EP S+ V+++GT K+ + +++L++E+FD RP + LDL++ ++ TAAYG Sbjct: 302 AIGIAEPTSISVETFGTSKLEESRLIELIREHFDLRPYGLIKMLDLER--PIYLPTAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKASA 1096 HFGR+ +F WE + DKA A Sbjct: 360 HFGRE--EFPWE-----RTDKAEA 376
>Q6LMM8:METK_PHOPR S-adenosylmethionine synthetase - Photobacterium profundum| (Photobacterium sp. (strain SS9)) Length = 384 Score = 314 bits (805), Expect = 5e-85 Identities = 179/372 (48%), Positives = 229/372 (61%), Gaps = 54/372 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MVMV GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG+++ ++G DA+ C VL I +QSPDI QGV + P E+GAGDQG Sbjct: 65 IEEITRETIREIGYVNSEMGFDANSCAVLSAIGKQSPDINQGVD---REDPRELGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 IMFGYA+DET LMP Sbjct: 122 IMFGYASDETDVLMPAPVTYAHRLVQRQAKVRKNGTLPWLRPDAKSQVTFAYDQGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKPV+PA++L + T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSDCIDLPVLQEAVMEEIIKPVLPAEWLTKETKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLASRCEIQLSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV +P S+ ++++GT K+ I+ V++NFD RP + LDL + + KTAAYG Sbjct: 302 AIGVADPTSIMIETFGTEKVSHDIIVDAVRQNFDLRPYGLIEMLDLLQ--PIYKKTAAYG 359 Query: 1025 HFGRDDADFTWE 1060 HFGR+ +F WE Sbjct: 360 HFGRE--EFPWE 369
>Q82WL2:METK_NITEU S-adenosylmethionine synthetase - Nitrosomonas europaea| Length = 387 Score = 314 bits (805), Expect = 5e-85 Identities = 176/385 (45%), Positives = 231/385 (60%), Gaps = 54/385 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQ+SDA+LDA L QD ++VACET+ T ++++ GEITT AT+ Sbjct: 4 YLFTSESVSEGHPDKVADQISDAILDAILQQDPHARVACETMCSTGLIVLSGEITTDATI 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 DY I R R IG+ S ++G DA C VL +QSPDIAQGV+ + ++ GAGDQ Sbjct: 64 DYNAIPRGIVREIGYTSSEIGFDASTCAVLTAFNKQSPDIAQGVNRSKDEEMDQ-GAGDQ 122 Query: 464 GIMFGYATDETPELMPLSHVLATKLGAR-------------------------------- 547 G+MFGYA DETP+LMPL A +L + Sbjct: 123 GLMFGYACDETPQLMPLPIYYAHRLVEQQAKLRKSGRLSWLRPDAKSQVSVRYEDGFPKN 182 Query: 548 ------------------LKEHVIKPVI----PAKYLDENTIFHLNPSGRFVIGGPHGDA 661 L E VI+ VI PA+ L + + +NP+GRFV+GGP GD Sbjct: 183 IETIVISTQHSPDVPRDELVEGVIEEVIKPVLPAEMLSNHIQYLINPTGRFVVGGPMGDC 242 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLAR+C VQ++ Sbjct: 243 GLTGRKIIVDTYGGTAHHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLARKCEVQVA 302 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIGV +P+S+ V ++GTGKIPD ++ +L+ +FD RP I LDL + + KTAAY Sbjct: 303 YAIGVAKPVSLMVQTFGTGKIPDGKLAELIARHFDLRPRAIIHELDLLR--PIYGKTAAY 360 Query: 1022 GHFGRDDADFTWEVVKPLKFDKASA 1096 GHFGR++ FTWE + KA A Sbjct: 361 GHFGREEPSFTWEKTDMAEQLKADA 385
>Q8Y6M0:METK_LISMO S-adenosylmethionine synthetase - Listeria monocytogenes| Length = 399 Score = 314 bits (804), Expect = 7e-85 Identities = 181/399 (45%), Positives = 231/399 (57%), Gaps = 63/399 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MA LFTSESV++GHPDK+ DQ+SDA+LDA +++D D++VACET T +V+V GEIT Sbjct: 1 MAKNRHLFTSESVSDGHPDKIADQISDAILDAIISKDPDARVACETTVTTGLVLVAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD KIVRDT + IG+ G DA+ C VL I++QSPDIAQGV R Sbjct: 61 TSVYVDIPKIVRDTIKEIGYTRAKYGFDAETCAVLTAIDEQSPDIAQGVDEALESRSGNE 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATK------------------- 535 E +GAGDQG+MFG+ATDET ELMPL +H LA K Sbjct: 121 IDAAIEAIGAGDQGLMFGFATDETEELMPLPIFLAHGLARKLTELRKTNKLDYLRPDAKT 180 Query: 536 --------------------------------LGARLKEHVIKPVIPAKYLDENTIFHLN 619 + L ++ VI A +LDE+T + +N Sbjct: 181 QVTVEYDEFNQPVRIDTIVVSTQHHPDITQEQIAKDLHTYLFPEVIDASFLDEDTKYFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KDPTKVDRSGAY AR AK+I Sbjct: 241 PTGRFVIGGPLGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSGAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA++ VQ++YAIGV P+S+ +D+YGT ++E++ V FD RP I LD Sbjct: 301 VAAGLAKKVEVQVAYAIGVARPVSISIDTYGTSDYSEQELIDGVNALFDLRPAGIIHMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 L++ R +TAA+GHFGR D D WE + DKA A Sbjct: 361 LRRPIYR--QTAAFGHFGRSDLDLPWE-----RTDKAEA 392
>Q8RCE4:METK_THETN S-adenosylmethionine synthetase - Thermoanaerobacter tengcongensis| Length = 395 Score = 313 bits (801), Expect = 2e-84 Identities = 172/380 (45%), Positives = 224/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+CDQ+SDA+LD L +D ++VACET T +V+V+GEITT+ VD Sbjct: 4 LFTSESVTEGHPDKICDQISDAILDEILKKDPYARVACETAVTTGLVLVMGEITTECYVD 63 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--------E 442 +I RD R+IG+ G DAD C V+ +I++QSPDIA GV+ R E Sbjct: 64 IPRIARDVIRDIGYTRAKYGFDADTCAVITSIDEQSPDIAMGVNKALEARRGELTDAEIE 123 Query: 443 EVGAGDQGIMFGYATDETPELMP----LSHVLATKLGARLK------------------- 553 +GAGDQG+M G+A DET ELMP L+H LA +L K Sbjct: 124 AIGAGDQGLMIGFACDETEELMPMPIMLAHKLARRLAEVRKNGTLSYLRPDGKTQVTVEY 183 Query: 554 -------------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 EHV+ +IP +D+NT +NP+GRFV+ Sbjct: 184 EEDRPVRVDSVVVSAQHAPEVDHDTIEKDIIEHVVNVIIPENMMDKNTKIFVNPTGRFVL 243 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP D+GLTGRKII+DTY KDPTKVDRS +Y AR AK+I+A+GLA+ Sbjct: 244 GGPQADSGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSASYAARYVAKNIVAAGLAK 303 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV PL V ++++GTGKI D +I ++VK+ FD RP I +LDL++ R Sbjct: 304 KCEVQVAYAIGVATPLEVEINTFGTGKISDEKISEIVKKVFDLRPAAIIRDLDLRRPIYR 363 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + AAYGHFGR D D WE Sbjct: 364 --QVAAYGHFGRHDLDLPWE 381
>Q5FAC0:METK_NEIG1 S-adenosylmethionine synthetase - Neisseria gonorrhoeae (strain ATCC| 700825 / FA 1090) Length = 389 Score = 312 bits (800), Expect = 2e-84 Identities = 180/388 (46%), Positives = 237/388 (61%), Gaps = 57/388 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQVSDA+LDA LAQD ++VA ET+ T + ++ GEITT A V Sbjct: 4 YLFTSESVSEGHPDKVADQVSDAILDAILAQDPKARVAAETLVNTGLCVLAGEITTTAQV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH-GHFTKRPEEVGAGD 460 DY K+ R+T + IG+ S ++G DA+ C V V +QQSPDIAQGV+ G + GAGD Sbjct: 64 DYIKVARETIKRIGYNSSELGFDANGCAVGVYYDQQSPDIAQGVNEGEGIDLNQ--GAGD 121 Query: 461 QGIMFGYATDETPELMPL----SH------------------------------------ 520 QG+MFGYA DETP LMP SH Sbjct: 122 QGLMFGYACDETPTLMPFAIYYSHRLMQRQSELRKDGRLPWLRPDAKAQLTVVYDSETGK 181 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E +IKPV+P + L + T + +NP+GRFVIGGP Sbjct: 182 VKRIDTVVLSTQHDPAISQEELSKAVIEQIIKPVLPPELLTDETKYLINPTGRFVIGGPQ 241 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA +C + Sbjct: 242 GDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYACRYVAKNIVAAGLATQCQI 301 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ +D++GTGKI + +++ LV E+FD RP I LDL + + K+ Sbjct: 302 QVSYAIGVAEPTSISIDTFGTGKISEEKLIALVCEHFDLRPKGIVQMLDLLR--PIYGKS 359 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 AAYGHFGR++ +FTWE + DKA++ Sbjct: 360 AAYGHFGREEPEFTWE-----RTDKAAS 382
>P66764:METK_SALTY S-adenosylmethionine synthetase - Salmonella typhimurium| Length = 384 Score = 312 bits (799), Expect = 3e-84 Identities = 182/382 (47%), Positives = 232/382 (60%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILQQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++P+++L+ +T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHAEDIDQKSLQEAVMEEIIKPILPSEWLNTSTKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P +++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPAEQLILLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ +F WE K DKA Sbjct: 360 HFGRE--NFPWE-----KTDKA 374
>P66765:METK_SALTI S-adenosylmethionine synthetase - Salmonella typhi| Length = 384 Score = 312 bits (799), Expect = 3e-84 Identities = 182/382 (47%), Positives = 232/382 (60%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILQQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++P+++L+ +T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHAEDIDQKSLQEAVMEEIIKPILPSEWLNTSTKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P +++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPAEQLILLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ +F WE K DKA Sbjct: 360 HFGRE--NFPWE-----KTDKA 374
>Q5PJJ2:METK_SALPA S-adenosylmethionine synthetase - Salmonella paratyphi-a| Length = 384 Score = 312 bits (799), Expect = 3e-84 Identities = 182/382 (47%), Positives = 232/382 (60%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILQQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++P+++L+ +T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHAEDIDQKSLQEAVMEEIIKPILPSEWLNTSTKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P +++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPAEQLILLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ +F WE K DKA Sbjct: 360 HFGRE--NFPWE-----KTDKA 374
>Q57K26:METK_SALCH S-adenosylmethionine synthetase - Salmonella choleraesuis| Length = 384 Score = 312 bits (799), Expect = 3e-84 Identities = 182/382 (47%), Positives = 232/382 (60%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILQQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++P+++L+ +T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHAEDIDQKSLQEAVMEEIIKPILPSEWLNTSTKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P +++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPAEQLILLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ +F WE K DKA Sbjct: 360 HFGRE--NFPWE-----KTDKA 374
>P31155:METK_PETCR S-adenosylmethionine synthetase 1 - Petroselinum crispum (Parsley)| (Petroselinum hortense) Length = 234 Score = 312 bits (799), Expect = 3e-84 Identities = 153/187 (81%), Positives = 165/187 (88%), Gaps = 1/187 (0%) Frame = +2 Query: 533 KLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXX 712 ++ A LKEHVIKPV+P YLDE TIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTY Sbjct: 48 EIAADLKEHVIKPVVPENYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGA 107 Query: 713 XXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYG 892 KDPTKVDRSGAYI RQAAKSI+ASGLARRCIVQ+SYAIGVPEPLSVFVD+YG Sbjct: 108 HGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASGLARRCIVQVSYAIGVPEPLSVFVDTYG 167 Query: 893 TGKIPDREILKLVKENFDFRPGMISINLDLKKGGN-RFIKTAAYGHFGRDDADFTWEVVK 1069 TGKIPDREILK+VKE FDFRPGMISINLDLK+GGN RF+KTAAYGHFGR+D DFTWEVVK Sbjct: 168 TGKIPDREILKIVKETFDFRPGMISINLDLKRGGNGRFLKTAAYGHFGREDPDFTWEVVK 227 Query: 1070 PLKFDKA 1090 PLK++KA Sbjct: 228 PLKWEKA 234
>O43938:METK_LEIIN S-adenosylmethionine synthetase - Leishmania infantum| Length = 392 Score = 312 bits (799), Expect = 3e-84 Identities = 189/392 (48%), Positives = 231/392 (58%), Gaps = 63/392 (16%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ + LF+SE V EGHPDKLCDQVSDAVLDACLA D SKVACE+ KT MVMV GEIT Sbjct: 1 MSVHSILFSSEHVTEGHPDKLCDQVSDAVLDACLAGDPFSKVACESCAKTGMVMVFGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSP------------DIAQG 412 TKA +DY+KIVR+T ++IGF S D GLD + C VLV IEQQSP D+ G Sbjct: 61 TKAVLDYQKIVRNTIKDIGFDSADKGLDYESCNVLVAIEQQSPDICQGLGNFDSEDLGAG 120 Query: 413 ----VHGHFTKRPE-------EVGAG-----------------------DQGIMFGYATD 490 + G+ T E E+ G + + Y T Sbjct: 121 DQGMMFGYATDETETLMPLTYELARGLAKKYSELRRSGSLEWARPDAKTQVTVEYDYDTR 180 Query: 491 E-----TPELMPL--------SHVLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGR 631 E TP+ + + HV K+ L E VIK VIPA LD T + LNPSGR Sbjct: 181 EGKQVLTPKRVAVVLISAQHDEHVTNDKISVDLMEKVIKAVIPANMLDAETKYWLNPSGR 240 Query: 632 FVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASG 811 FV GGPHGDAGLTGRKII+DTY KDP+KVDRS AY AR AKSI+A G Sbjct: 241 FVRGGPHGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPSKVDRSAAYAARWIAKSIVAGG 300 Query: 812 LARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKG 991 LARRC+VQ++YAIGV EPLS+ V++YGTGK D ++L++VK+NF RP I L+L++ Sbjct: 301 LARRCLVQLAYAIGVAEPLSMHVETYGTGKYDDAKLLEIVKQNFKLRPYDIIQELNLRR- 359 Query: 992 GNRFIKTAAYGHFGRDD----ADFTWEVVKPL 1075 + T+ +GHFGR D FTWEV K + Sbjct: 360 -PIYYDTSRFGHFGRKDELGTGGFTWEVPKKM 390
>Q476V0:METK_RALEJ S-adenosylmethionine synthetase - Ralstonia eutropha (strain JMP134)| (Alcaligenes eutrophus) Length = 387 Score = 311 bits (798), Expect = 3e-84 Identities = 182/388 (46%), Positives = 237/388 (61%), Gaps = 54/388 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A FLFTSESV+EGHPDK+ DQ+SDAVLDA LAQD ++VA ET+ T +V++ GEITT Sbjct: 2 ANDFLFTSESVSEGHPDKVADQISDAVLDAILAQDKYARVAAETLCNTGLVVLAGEITTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VDY ++ RDT + IG+ + + G+D C VLV ++QSPDIAQGV + GA Sbjct: 62 ANVDYIQVARDTIKRIGYDNTEYGIDYKGCAVLVAYDKQSPDIAQGVDRASDDYLNQ-GA 120 Query: 455 GDQGIMFGYATDETPELMPL----SH---------------------------------- 520 GDQG+MFGYA DETPELMP SH Sbjct: 121 GDQGLMFGYACDETPELMPFPIYYSHRLVERQSQLRRDGRLPWLRPDAKSQVTVRYVDGR 180 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ + + E +IKPV+P + L ++T + +NP+GRFVIGGP Sbjct: 181 PHSVDTVVLSTQHAPDITQAQIREAVIEEIIKPVLPPEML-KDTKYLVNPTGRFVIGGPQ 239 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLAR+C V Sbjct: 240 GDCGLTGRKIIVDTYGGASPHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLARQCQV 299 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV P++V V + GTGKI D +I +LV+E+FD RP I LDL + + KT Sbjct: 300 QVSYAIGVARPINVTVYTEGTGKISDAKIAELVQEHFDLRPKGIVQMLDLLR--PIYEKT 357 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 AAYGHFGR++ +F+WE +A+A Sbjct: 358 AAYGHFGREEPEFSWEATDKAAILRAAA 385
>Q31WK4:METK_SHIBS S-adenosylmethionine synthetase - Shigella boydii serotype 4 (strain| Sb227) Length = 384 Score = 311 bits (797), Expect = 4e-84 Identities = 183/382 (47%), Positives = 228/382 (59%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++PA++L T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATTFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P ++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ F WE K DKA Sbjct: 360 HFGRE--HFPWE-----KTDKA 374
>Q2NRD1:METK_SODGM S-adenosylmethionine synthetase - Sodalis glossinidius (strain| morsitans) Length = 385 Score = 311 bits (796), Expect = 6e-84 Identities = 185/382 (48%), Positives = 230/382 (60%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA LAQD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILAQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E++ R T R IG+I D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEELTRSTIREIGYIHSDMGFDANSCAVLSAIGKQSPDINQGVD---RTDPLEQGAGDQG 121 Query: 467 IMFGYATDETPELM--PLSH---------------------------------------- 520 +MFGYAT+ET LM P+++ Sbjct: 122 MMFGYATNETDVLMPAPITYAHRLVARQSQVRKNGTLPWLRPDAKSQVTFAYDNGKVVGI 181 Query: 521 ---VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 VL+T+ L + E +IKPV+PA++L T + +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHAEDIALPQLKEAVMEEIIKPVLPAEWLSAQTKYFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLAERCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ ++++GT KIP + LV+E FD RP + LDL + R +TAAYG Sbjct: 302 AIGVAEPTSITIETFGTEKIPADNLTALVREFFDLRPHGLITMLDLLQPIYR--ETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ F WE K DKA Sbjct: 360 HFGRE--HFPWE-----KTDKA 374
>Q837P9:METK_ENTFA S-adenosylmethionine synthetase - Enterococcus faecalis| (Streptococcus faecalis) Length = 394 Score = 311 bits (796), Expect = 6e-84 Identities = 176/391 (45%), Positives = 237/391 (60%), Gaps = 59/391 (15%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E LFTSESV+EGHPDK+ DQVSDA+LDA L +D ++VACET T +V+V GEI+T A Sbjct: 3 ERHLFTSESVSEGHPDKVADQVSDAILDAILEKDPMARVACETSVTTGLVLVFGEISTTA 62 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE---- 445 VD +KIVR T ++IG+ G D + VLV I++QSPDIAQGV R ++ Sbjct: 63 YVDIQKIVRQTVKDIGYTRAKYGFDGETVAVLVAIDEQSPDIAQGVDAALEVRDQDEKDD 122 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 +GAGDQG+MFG+A DETPELMP LSH Sbjct: 123 IGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRLAELRKEKVLPYLRPDAKSQVTVEYD 182 Query: 521 -----------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 V++T+ + +KE VI VIP + LD+ T + +NP+GRFVI Sbjct: 183 DQGQPQRVDTIVISTQHDDETTLEQIEKDIKEQVINEVIPHELLDDETKYFINPTGRFVI 242 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KD TKVDRS +Y AR AK+I+A+GLA+ Sbjct: 243 GGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLAK 302 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 + VQ++YAIGV +P+S+ ++++GT +P+ ++++ V++NFD RP I LDL++ Sbjct: 303 KVEVQLAYAIGVAQPVSISINTFGTSDLPESKLIEAVRKNFDLRPAGIIEMLDLRR--PI 360 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKAS 1093 + +TAAYGHFGR D D WE ++ KAS Sbjct: 361 YKQTAAYGHFGRTDIDLPWEQTDKVEALKAS 391
>Q3YXS9:METK_SHISS S-adenosylmethionine synthetase - Shigella sonnei (strain Ss046)| Length = 384 Score = 310 bits (795), Expect = 8e-84 Identities = 183/382 (47%), Positives = 228/382 (59%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++PA++L T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P ++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ F WE K DKA Sbjct: 360 HFGRE--HFPWE-----KTDKA 374
>P0A820:METK_SHIFL S-adenosylmethionine synthetase - Shigella flexneri| Length = 384 Score = 310 bits (795), Expect = 8e-84 Identities = 183/382 (47%), Positives = 228/382 (59%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++PA++L T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P ++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ F WE K DKA Sbjct: 360 HFGRE--HFPWE-----KTDKA 374
>Q32C11:METK_SHIDS S-adenosylmethionine synthetase - Shigella dysenteriae serotype 1| (strain Sd197) Length = 384 Score = 310 bits (795), Expect = 8e-84 Identities = 183/382 (47%), Positives = 228/382 (59%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++PA++L T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P ++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ F WE K DKA Sbjct: 360 HFGRE--HFPWE-----KTDKA 374
>P0A817:METK_ECOLI S-adenosylmethionine synthetase - Escherichia coli| Length = 384 Score = 310 bits (795), Expect = 8e-84 Identities = 183/382 (47%), Positives = 228/382 (59%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++PA++L T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P ++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ F WE K DKA Sbjct: 360 HFGRE--HFPWE-----KTDKA 374
>P0A818:METK_ECOL6 S-adenosylmethionine synthetase - Escherichia coli O6| Length = 384 Score = 310 bits (795), Expect = 8e-84 Identities = 183/382 (47%), Positives = 228/382 (59%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++PA++L T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P ++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ F WE K DKA Sbjct: 360 HFGRE--HFPWE-----KTDKA 374
>P0A819:METK_ECO57 S-adenosylmethionine synthetase - Escherichia coli O157:H7| Length = 384 Score = 310 bits (795), Expect = 8e-84 Identities = 183/382 (47%), Positives = 228/382 (59%), Gaps = 54/382 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R+T R IG++ D+G DA+ C VL I +QSPDI QGV P E GAGDQG Sbjct: 65 IEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RADPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKP++PA++L T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT K+P ++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLH--PIYKETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKA 1090 HFGR+ F WE K DKA Sbjct: 360 HFGRE--HFPWE-----KTDKA 374
>Q83A78:METK_COXBU S-adenosylmethionine synthetase - Coxiella burnetii| Length = 393 Score = 310 bits (795), Expect = 8e-84 Identities = 172/374 (45%), Positives = 227/374 (60%), Gaps = 54/374 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 T LFTSESV+EGHPDK+ DQ+SDAVLDA + QD + +VACE V K+ MV V GEITT A Sbjct: 4 TTLFTSESVSEGHPDKVADQISDAVLDALIGQDPNCRVACEAVVKSGMVFVAGEITTNAW 63 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 D E+I R+T IG+ +G D + C V+ I +QSPDI GV G + +E+GAGD Sbjct: 64 ADVEQITRNTVLQIGYNDPHLGFDGETCAVVTAIGKQSPDIVMGVDG---REDQELGAGD 120 Query: 461 QGIMFGYATDETPELM--PLSH-------------------------------------- 520 QG+MFGYA+ ET M P+++ Sbjct: 121 QGLMFGYASRETNVFMPAPITYAHRLVRQQALLRKNGRLPWLRPDAKSQVTLRYENGKPV 180 Query: 521 -----VLATKLGARLKEH---------VIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGD 658 VL+T+ + + +IKP++P +LD++T F +NP+GRFVIGGP GD Sbjct: 181 AADCIVLSTQHSPEISQESLREAVIDEIIKPIMPPHWLDKHTRFLVNPTGRFVIGGPVGD 240 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 GLTGRKII+DTY KDP+KVDRSGAY AR AK+I+A GLA RC +Q+ Sbjct: 241 CGLTGRKIIVDTYGGMARHGGGCFSGKDPSKVDRSGAYAARYVAKNIVAGGLADRCEIQV 300 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAA 1018 SYAIGV EP S+ V+++GTGKI + I +L+KE+FD RPG I L+L + + + TA Sbjct: 301 SYAIGVAEPTSISVETFGTGKIDEVRIQQLIKEHFDLRPGKIIEELNLLR--SIYKATAT 358 Query: 1019 YGHFGRDDADFTWE 1060 YGHFGR++ +FTWE Sbjct: 359 YGHFGREEPEFTWE 372
>Q8K9E5:METK_BUCAP S-adenosylmethionine synthetase - Buchnera aphidicola subsp.| Schizaphis graminum Length = 379 Score = 310 bits (795), Expect = 8e-84 Identities = 173/373 (46%), Positives = 225/373 (60%), Gaps = 54/373 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQ+SDA+LD + QD ++VACET KT MV++ GEITT A V Sbjct: 4 YLFTSESVSEGHPDKIADQISDALLDEIIKQDLKARVACETYVKTGMVLIGGEITTTAWV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 D E+I R+T NIG+I+ + G DA+ C VL I +QSPDI QGV P E GAGDQ Sbjct: 64 DVEEITRNTINNIGYINSETGFDANSCAVLSTIGKQSPDITQGVD---RCNPLEQGAGDQ 120 Query: 464 GIMFGYATDETPELMPL----SHVLATK-------------------------------- 535 GI+FGYAT+ET LMP +H+L K Sbjct: 121 GIIFGYATNETEVLMPAPITYAHLLVKKQSELRKKNILHWLRPDAKSQVTFKYKNGRIIG 180 Query: 536 ------------------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDA 661 L + E +IKPV+P K+L +NT F +NP+GRFVIGGP GD Sbjct: 181 IDTVVFSTQHKESITQDVLKEAVMEEIIKPVLPNKWLTKNTKFFINPTGRFVIGGPMGDC 240 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+S Sbjct: 241 GLTGRKIIVDTYGGMSRHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQLS 300 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIG+ EP S+ ++++ TGKI ++ ++ LV+ FD RP + LDL + ++ TA Y Sbjct: 301 YAIGIAEPTSIMIETFRTGKISNKSLINLVRNIFDLRPYGLIEMLDLLR--PIYLNTAVY 358 Query: 1022 GHFGRDDADFTWE 1060 GHFGR+ +F WE Sbjct: 359 GHFGRE--EFPWE 369
>Q666P5:METK_YERPS S-adenosylmethionine synthetase - Yersinia pseudotuberculosis| Length = 384 Score = 310 bits (793), Expect = 1e-83 Identities = 183/383 (47%), Positives = 230/383 (60%), Gaps = 54/383 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GE+TT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEVTTNAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R T R IG++ D+G DA+ C VL I +QSPDI QGV + P E GAGDQG Sbjct: 65 IEEITRRTIREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RENPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETSVLMPAPITYAHRLVERQAEVRKNGALPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKPV+PA+++ +T + +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEDINQKDLHEAVMEEIIKPVLPAEWITAHTKYFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT KIP ++ LV+E FD RP + LDL R +TAAYG Sbjct: 302 AIGVAEPTSIMVEAFGTEKIPADQLTLLVREFFDLRPYGLIKMLDLLHPIYR--ETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKAS 1093 HFGR+ F WE K DKA+ Sbjct: 360 HFGRE--HFPWE-----KTDKAA 375
>Q8ZHG7:METK_YERPE S-adenosylmethionine synthetase - Yersinia pestis| Length = 384 Score = 310 bits (793), Expect = 1e-83 Identities = 183/383 (47%), Positives = 230/383 (60%), Gaps = 54/383 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GE+TT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEVTTNAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R T R IG++ D+G DA+ C VL I +QSPDI QGV + P E GAGDQG Sbjct: 65 IEEITRRTIREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVD---RENPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYAT+ET LMP Sbjct: 122 LMFGYATNETSVLMPAPITYAHRLVERQAEVRKNGALPWLRPDAKSQVTFQYDDGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKPV+PA+++ +T + +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEDINQKDLHEAVMEEIIKPVLPAEWITAHTKYFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ V+++GT KIP ++ LV+E FD RP + LDL R +TAAYG Sbjct: 302 AIGVAEPTSIMVEAFGTEKIPADQLTLLVREFFDLRPYGLIKMLDLLHPIYR--ETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKAS 1093 HFGR+ F WE K DKA+ Sbjct: 360 HFGRE--HFPWE-----KTDKAA 375
>Q486L6:METK_COLP3 S-adenosylmethionine synthetase - Colwellia psychrerythraea (strain| 34H / ATCC BAA-681) (Vibrio psychroerythus) Length = 395 Score = 310 bits (793), Expect = 1e-83 Identities = 172/369 (46%), Positives = 227/369 (61%), Gaps = 54/369 (14%) Frame = +2 Query: 110 FTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVDY 289 FTSESV+EGHPDK+ DQ+SDAVLDA +A+D ++VACET+ KT + ++ GE++T A VD Sbjct: 6 FTSESVSEGHPDKIADQISDAVLDAIIAKDKHARVACETMVKTGVAIISGEVSTNAWVDL 65 Query: 290 EKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQGI 469 EK+ R+ +IG+ S DVG D C ++ I QQSP+IAQGV PEE GAGDQG+ Sbjct: 66 EKLTRNVISDIGYTSSDVGFDGATCGIMNLIGQQSPEIAQGVD---RSNPEEQGAGDQGL 122 Query: 470 MFGYATDETPELMPL----SH--------------------------------------- 520 MFGYAT+ETP LMP SH Sbjct: 123 MFGYATNETPTLMPAPLYYSHRLVERQAEARKSGVLPWLRPDAKSQVTFIYEDNKPVAID 182 Query: 521 --VLATKLGARLK---------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAGL 667 VL+T+ +K E++I V+PA+ L E+T +H+NP+GRFVIGGP GD GL Sbjct: 183 TVVLSTQHNPDIKQEDLVSAVMENIINHVLPAELLTEDTKYHINPTGRFVIGGPVGDCGL 242 Query: 668 TGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYA 847 TGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA RC +QISYA Sbjct: 243 TGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLADRCEIQISYA 302 Query: 848 IGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYGH 1027 IGV EP S+ +D++GTG I + ++++V+E+FD RP I+ LDL + +TAAYGH Sbjct: 303 IGVAEPTSISIDTFGTGSISEERLVEIVREHFDLRPYGITKMLDLLH--PMYQQTAAYGH 360 Query: 1028 FGRDDADFT 1054 FGR+ + T Sbjct: 361 FGREPFEMT 369
>Q6MPK2:METK_BDEBA S-adenosylmethionine synthetase - Bdellovibrio bacteriovorus| Length = 387 Score = 310 bits (793), Expect = 1e-83 Identities = 170/375 (45%), Positives = 220/375 (58%), Gaps = 54/375 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 + +LFTSESV+EGHPDK+ DQ+SD +LDA LAQD +VACET+ T +V+V GEITT A Sbjct: 2 KNYLFTSESVSEGHPDKMADQISDGILDAILAQDPKGRVACETLLTTGLVVVAGEITTSA 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 V++ ++ RD + IG+ D G D C V++ + QQSPDIA GV + + GAG Sbjct: 62 KVNFSEVARDVVKRIGYDHSDKGFDYKTCGVMIAVGQQSPDIAVGVKETLS---DNQGAG 118 Query: 458 DQGIMFGYATDETPELMPLS----HVLATKLGARLK------------------------ 553 DQG+MFGYA +ETPELMPLS H L L A K Sbjct: 119 DQGLMFGYAVNETPELMPLSIAMSHKLVKDLAALRKANKVDWLRPDAKSQVTVQYENGIA 178 Query: 554 --------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 E +IK IP ++D T F +NP+GRFV GGP G Sbjct: 179 KRIDAVVISTQHADSVSNSTIQEFITEELIKKSIPGNWIDSKTKFFINPTGRFVTGGPMG 238 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 DAGLTGRKII+DTY KDP+KVDRS AY +R AK+I+ +GLA RC+VQ Sbjct: 239 DAGLTGRKIIVDTYGGHGAHGGGAFSGKDPSKVDRSAAYASRHIAKNIVGAGLAERCLVQ 298 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 ++YAIGV EP+S+ V+ YGT K+ + K V++ FD RP I+ +LDL + + TA Sbjct: 299 VAYAIGVAEPVSITVNDYGTSKVGPEVLEKAVRQVFDLRPARITKDLDLLR--PIYSPTA 356 Query: 1016 AYGHFGRDDADFTWE 1060 AYGHFGR++ FTWE Sbjct: 357 AYGHFGRNEESFTWE 371
>P54419:METK_BACSU S-adenosylmethionine synthetase - Bacillus subtilis| Length = 400 Score = 309 bits (792), Expect = 2e-83 Identities = 171/387 (44%), Positives = 225/387 (58%), Gaps = 63/387 (16%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ LFTSESV EGHPDK+CDQ+SD++LD L +D +++VACET T +V+V GEIT Sbjct: 1 MSKNRRLFTSESVTEGHPDKICDQISDSILDEILKKDPNARVACETSVTTGLVLVSGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD K VR T + IG+ G DA+ C VL +I++QS DIA GV R Sbjct: 61 TSTYVDIPKTVRQTIKEIGYTRAKYGFDAETCAVLTSIDEQSADIAMGVDQALEAREGTM 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGA---------------- 544 E +GAGDQG+MFGYA +ET ELMPL +H LA +L Sbjct: 121 SDEEIEAIGAGDQGLMFGYACNETKELMPLPISLAHKLARRLSEVRKEDILPYLRPDGKT 180 Query: 545 -----------------------------------RLKEHVIKPVIPAKYLDENTIFHLN 619 +KEHVI PV+P + +DE T + +N Sbjct: 181 QVTVEYDENNKPVRIDAIVISTQHHPEITLEQIQRNIKEHVINPVVPEELIDEETKYFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GDAGLTGRKII+DTY KD TKVDRS AY AR AK+I Sbjct: 241 PTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+ LA C VQ++YAIGV +P+S+ ++++G+GK + +++++V+ NFD RP I LD Sbjct: 301 VAAELADSCEVQLAYAIGVAQPVSISINTFGSGKASEEKLIEVVRNNFDLRPAGIIKMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWE 1060 L++ + +TAAYGHFGR D D WE Sbjct: 361 LRR--PIYKQTAAYGHFGRHDVDLPWE 385
>Q7N119:METK_PHOLL S-adenosylmethionine synthetase - Photorhabdus luminescens subsp.| laumondii Length = 390 Score = 308 bits (790), Expect = 3e-83 Identities = 183/386 (47%), Positives = 228/386 (59%), Gaps = 54/386 (13%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 T+LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MVMV GEITT A Sbjct: 3 TYLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEITTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 VD E+I R T R IG+++ ++G DA+ C VL I +QSPDI QGV + P + GAGD Sbjct: 63 VDIEEITRQTVREIGYVNSEMGFDANSCAVLSAIGKQSPDINQGVD---REDPLQQGAGD 119 Query: 461 QGIMFGYATDETPELMPL------------------------------------------ 514 QG+MFGYAT+ET LMP Sbjct: 120 QGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGVLPWLRPDAKSQVTFQYNNDKIV 179 Query: 515 ---SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGD 658 + VL+T+ L + E +IKPV+PA++L+ T + +NP+GRFVIGGP GD Sbjct: 180 GVDAVVLSTQHAENISQKDLQEAVMEEIIKPVLPAEWLNPTTKYFINPTGRFVIGGPMGD 239 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+ Sbjct: 240 CGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQV 299 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAA 1018 SYAIGV EP S+ V+++GT K+ + LV+E FD RP + LDL R TAA Sbjct: 300 SYAIGVAEPTSIMVETFGTEKVSTATLTLLVREFFDLRPHGLIQMLDLLHPIYR--DTAA 357 Query: 1019 YGHFGRDDADFTWEVVKPLKFDKASA 1096 YGHFGR F WE DKA A Sbjct: 358 YGHFGR--PQFPWEAT-----DKAEA 376
>Q9JVV6:METK_NEIMA S-adenosylmethionine synthetase - Neisseria meningitidis serogroup A| Length = 389 Score = 308 bits (790), Expect = 3e-83 Identities = 177/388 (45%), Positives = 235/388 (60%), Gaps = 57/388 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQVSDA+LDA LAQD ++VA ET+ T + ++ GEITT A V Sbjct: 4 YLFTSESVSEGHPDKVADQVSDAILDAILAQDPKARVAAETLVNTGLCVLAGEITTTAQV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH-GHFTKRPEEVGAGD 460 DY K+ R+T + IG+ S ++G DA+ C V V +QQSPDIAQGV+ G + GAGD Sbjct: 64 DYIKVARETIKRIGYNSSELGFDANGCAVGVYYDQQSPDIAQGVNEGEGIDLNQ--GAGD 121 Query: 461 QGIMFGYATDETPELMPLSHVLATKLGAR------------------------------- 547 QG+MFGYA DETP LMP + + +L R Sbjct: 122 QGLMFGYACDETPTLMPFAIYYSHRLMQRQSELRKDGRLPWLRPDAKAQLTVVYDSETGK 181 Query: 548 ---------------------LKEHVIKPVI----PAKYLDENTIFHLNPSGRFVIGGPH 652 LK VI+ +I P++ L + T + +NP+GRFVIGGP Sbjct: 182 VKRIDTVVLSTQHDPSVGYEELKNAVIEQIIKPVLPSELLTDETKYLINPTGRFVIGGPQ 241 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA +C + Sbjct: 242 GDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYACRYVAKNIVAAGLATQCQI 301 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ +D++GTGKI + +++ LV+E+FD RP I LDL + + K+ Sbjct: 302 QVSYAIGVAEPTSISIDTFGTGKISEEKLITLVREHFDLRPKGIVQMLDLLR--PIYSKS 359 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 AAYGHFGR++ +FTWE + DKA+A Sbjct: 360 AAYGHFGREEPEFTWE-----RTDKAAA 382
>Q74KS4:METK_LACJO S-adenosylmethionine synthetase - Lactobacillus johnsonii| Length = 402 Score = 308 bits (790), Expect = 3e-83 Identities = 173/387 (44%), Positives = 231/387 (59%), Gaps = 63/387 (16%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M E LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D D +VACET T +V+V+GEI+ Sbjct: 1 MKKEKRLFTSESVSEGHPDKVADQISDAILDAILAKDPDGRVACETTVTTGLVLVVGEIS 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T A VD + +VR T IG+ ++G D + C +LV+I++QS DIA GV+ R Sbjct: 61 TSAYVDIQSVVRKTILEIGYNRPELGFDGNNCAILVDIDEQSSDIADGVNESLETRENQQ 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLKEH----------- 559 +++GAGDQG+MFG+A ETPELMPL +H L ++ + KE Sbjct: 121 DKDDLDKIGAGDQGLMFGFAIKETPELMPLPISLAHSLMRRVASLRKEGRLDWLRPDAKA 180 Query: 560 ----------------------------------------VIKPVIPAKYLDENTIFHLN 619 VIK VIP++YLD++T F +N Sbjct: 181 QVTVEYDDENKPKRIDTVVISTQTDATVSNDEIREAMIDMVIKKVIPSQYLDKDTKFLIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 PSGRFVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I Sbjct: 241 PSGRFVIGGPKGDSGLTGRKIIVDTYGGYARHGGGAFSGKDLTKVDRSASYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA +C +Q++YAIGV P+S+ VD++GT K+ + +++ V+ FD RP I L+ Sbjct: 301 VAAGLAYQCEIQLAYAIGVAHPVSIMVDTHGTSKVSEDLLVEAVRNVFDLRPAGIIEMLN 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWE 1060 LK+ R +TAAYGHFGR D D WE Sbjct: 361 LKRPIYR--QTAAYGHFGRTDVDLPWE 385
>Q6D081:METK_ERWCT S-adenosylmethionine synthetase - Erwinia carotovora subsp.| atroseptica (Pectobacterium atrosepticum) Length = 383 Score = 308 bits (790), Expect = 3e-83 Identities = 182/383 (47%), Positives = 233/383 (60%), Gaps = 54/383 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MV+V GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R T R+IG+++ ++G DA+ C VL I +QSPDI QGV + P E GAGDQG Sbjct: 65 IEEITRRTVRDIGYVNSEMGFDANSCAVLSAIGKQSPDINQGVD---RRDPLEQGAGDQG 121 Query: 467 IMFGYATDETPELMP--------LSH---------------------------------- 520 +MFGYAT+ET LMP L H Sbjct: 122 LMFGYATNETDVLMPAPVTYAHRLVHRQSEVRKSGSLPWLRPDAKSQVTFLYDDGKIAGI 181 Query: 521 ---VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 VL+T+ L + E +IKPV+PA++L +T + +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHSEDVSQKDLHEAVMEEIIKPVLPAEWLSASTKYFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ ++++GT K+ + ++ LV+E FD RP + LDL + +TAAYG Sbjct: 302 AIGVAEPTSIMIETFGTEKVSNEQLTLLVREFFDLRPYGLIQMLDLLH--PIYQETAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKAS 1093 HFGR+ F WE K DKA+ Sbjct: 360 HFGRE--HFPWE-----KTDKAA 375
>Q9JY09:METK_NEIMB S-adenosylmethionine synthetase - Neisseria meningitidis serogroup B| Length = 389 Score = 308 bits (789), Expect = 4e-83 Identities = 177/388 (45%), Positives = 235/388 (60%), Gaps = 57/388 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQVSDA+LDA LAQD ++VA ET+ T + ++ GEITT A V Sbjct: 4 YLFTSESVSEGHPDKVADQVSDAILDAILAQDPKARVAAETLVNTGLCVLAGEITTTAQV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH-GHFTKRPEEVGAGD 460 DY K+ R+T + IG+ S ++G DA+ C V V +QQSPDIAQGV+ G + GAGD Sbjct: 64 DYIKVARETIKRIGYNSSELGFDANGCAVGVYYDQQSPDIAQGVNEGEGIDLNQ--GAGD 121 Query: 461 QGIMFGYATDETPELMPLSHVLATKLGAR------------------------------- 547 QG+MFGYA DETP LMP + + +L R Sbjct: 122 QGLMFGYACDETPTLMPFAIYYSHRLMQRQSELRKDGRLPWLRPDAKAQLTVVYDSETGK 181 Query: 548 ---------------------LKEHVIKPVI----PAKYLDENTIFHLNPSGRFVIGGPH 652 LK VI+ +I P++ L + T + +NP+GRFVIGGP Sbjct: 182 VKRIDTVVLSTQHDPSIAYEELKNAVIEHIIKPVLPSELLTDETKYLINPTGRFVIGGPQ 241 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA +C + Sbjct: 242 GDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYACRYVAKNIVAAGLATQCQI 301 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ +D++GTGKI + +++ LV+E+FD RP I LDL + + K+ Sbjct: 302 QVSYAIGVAEPTSISIDTFGTGKISEEKLIALVREHFDLRPKGIVQMLDLLR--PIYSKS 359 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 AAYGHFGR++ +FTWE + DKA+A Sbjct: 360 AAYGHFGREEPEFTWE-----RTDKAAA 382
>Q87LK6:METK_VIBPA S-adenosylmethionine synthetase - Vibrio parahaemolyticus| Length = 384 Score = 308 bits (788), Expect = 5e-83 Identities = 176/372 (47%), Positives = 225/372 (60%), Gaps = 54/372 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MVMV GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E++ R+T R IG++ D+G DA+ C VL I +QSPDI QGV P+E GAGDQG Sbjct: 65 IEELTRETVREIGYVHSDMGFDANSCAVLNTIGKQSPDINQGVD---KADPKEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL----SHVLATK--------------------------------- 535 IMFGYA +ET LMP SH L K Sbjct: 122 IMFGYACNETEVLMPAPITYSHRLVEKQAEVRKNGTLPWLRPDAKSQVTFQYDQGKIVGI 181 Query: 536 -----------------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 L + E +IKPV+PA+++ ++T F +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHCDSISTPDLREAVMEEIIKPVLPAEWISKDTNFFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+G+A RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGMADRCEIQLSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV +P S+ V+++GT K+ I++ V++ FD RP + L+L + + KTAAYG Sbjct: 302 AIGVADPTSIMVETFGTEKVSHDIIIEAVRQFFDLRPYGLQEMLNLLQ--PIYKKTAAYG 359 Query: 1025 HFGRDDADFTWE 1060 HFGR+ +F WE Sbjct: 360 HFGRE--EFPWE 369
>Q9KUP3:METK_VIBCH S-adenosylmethionine synthetase - Vibrio cholerae| Length = 385 Score = 307 bits (787), Expect = 6e-83 Identities = 176/372 (47%), Positives = 225/372 (60%), Gaps = 54/372 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA QD ++VACET KT MVMV GEITT A VD Sbjct: 6 LFTSESVSEGHPDKIADQISDAVLDAIFEQDPKARVACETYVKTGMVMVGGEITTSAWVD 65 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+I R T R IG++ D+G DA+ C VL I +QSPDI QGV P+E GAGDQG Sbjct: 66 IEEITRQTVREIGYVHSDMGFDANSCAVLNTIGKQSPDINQGVD---KADPKEQGAGDQG 122 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 IMFGYAT+ET LMP Sbjct: 123 IMFGYATNETEVLMPAPITYAHRLMQRQAAVRKNGTLPWLRPDAKSQVTFQYDQGKIVGI 182 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKPV+PA++L + T + +NP+GRFVIGGP GD G Sbjct: 183 DAVVLSTQHSDSISTADLREAVMEEIIKPVLPAEWLSKETKYFINPTGRFVIGGPMGDCG 242 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+G+A RC +Q+SY Sbjct: 243 LTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGMADRCEIQLSY 302 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV +P S+ V+++GT K+ I++ V++ FD RP + L+L + + KTAAYG Sbjct: 303 AIGVADPTSIMVETFGTEKVSQEIIIEAVRQFFDLRPYGLQEMLNLLQ--PIYKKTAAYG 360 Query: 1025 HFGRDDADFTWE 1060 HFGR+ +F WE Sbjct: 361 HFGRE--EFPWE 370
>Q9X1Y8:METK_THEMA S-adenosylmethionine synthetase - Thermotoga maritima| Length = 395 Score = 307 bits (787), Expect = 6e-83 Identities = 175/380 (46%), Positives = 223/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQ+SDA+LDA L QD S+VA ET+ T +V++ GE+TT+A V+ Sbjct: 4 LFTSESVTEGHPDKIADQISDAILDAMLEQDPRSRVAVETLVTTGLVIIAGEVTTRAYVE 63 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHF-TKRPEEV----- 448 I R T IG+ G D + C VL +I QSPDIA GV K EEV Sbjct: 64 IPDIARKTILEIGYTRAKYGFDGETCGVLTSIHSQSPDIALGVDKALEVKTGEEVADEFE 123 Query: 449 --GAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK------------------- 553 GAGDQGIMFGYAT+ETPE MPL +H LA +L K Sbjct: 124 ALGAGDQGIMFGYATNETPEYMPLPITLAHKLAMRLAEVRKNGTLPFLRPDGKTQVTIEY 183 Query: 554 -------------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 EHVI PVIP +Y D+ +NP+GRFV+ Sbjct: 184 EDDKPVRVDTVLISTQHDPDISQADLREAIIEHVINPVIPEQYRDDKMKILVNPTGRFVL 243 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP D GLTGRKII+DTY KDPTKVDRS Y+AR AK+++A+GLA Sbjct: 244 GGPMADTGLTGRKIIVDTYGGWVPHGGGAFSGKDPTKVDRSAHYMARYVAKNVVAAGLAD 303 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 + ++Q+SYAIGV +P+S+ +D+YGT K+ + ++LK++ E FDFRPG I L+L + R Sbjct: 304 KFLIQLSYAIGVAKPVSIMIDTYGTAKVDEDKLLKVITELFDFRPGAIIKKLNLLRPIYR 363 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 KTAAYGHFGR++ +FTWE Sbjct: 364 --KTAAYGHFGRNEEEFTWE 381
>Q21NJ5:METK_SACD2 S-adenosylmethionine synthetase - Saccharophagus degradans (strain| 2-40 / ATCC 43961 / DSM 17024) Length = 382 Score = 307 bits (787), Expect = 6e-83 Identities = 178/388 (45%), Positives = 227/388 (58%), Gaps = 54/388 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A+ LFTSESV+EGHPDK+ DQ+SDA+LDA LA D +++VA ET+ KT M +V GE+ T Sbjct: 2 AQYSLFTSESVSEGHPDKMADQISDAILDAILADDKNARVAVETMVKTGMAIVAGEVRTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 +D E ++RD +IG+ S DVG D C VL I +QS DIA GV K ++GA Sbjct: 62 TYIDLEDLIRDVILDIGYNSSDVGFDGASCAVLNAIGKQSADIAMGVDEANNK---DLGA 118 Query: 455 GDQGIMFGYATDETPELMPL----SHVLATKLGARLK----------------------- 553 GDQG+MFGYAT+ET LMP SH L K K Sbjct: 119 GDQGLMFGYATNETDVLMPAPIYYSHRLVEKQAELRKNGKLNWLRPDAKSQVTLRYDNGK 178 Query: 554 ---------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 E +IK +PA++L +T +H+NP+G+F+IGGP Sbjct: 179 PVAVDAVVLSTQHNPDVSQATIREAVMEEIIKTTLPAEWLHADTKYHINPTGQFIIGGPV 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA RC + Sbjct: 239 GDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRCEI 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ V+++GTG I D EI KLV ++FD RP I LDL + R KT Sbjct: 299 QVSYAIGVAEPTSISVNTFGTGSIADSEISKLVAQHFDLRPRGIIEMLDLLRPIYR--KT 356 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 AAYGHFGR++ +FTWE K DK +A Sbjct: 357 AAYGHFGREEPEFTWE-----KTDKVAA 379
>Q4FTH7:METK_PSYAR S-adenosylmethionine synthetase - Psychrobacter arcticum| Length = 388 Score = 307 bits (787), Expect = 6e-83 Identities = 173/386 (44%), Positives = 234/386 (60%), Gaps = 56/386 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDA+LDA L QD ++VACET+ KT V++ GEITT A +D Sbjct: 6 LFTSESVSEGHPDKMADQISDAILDAILRQDLHARVACETLVKTGAVILAGEITTTANID 65 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+IVRDT IG+ D+G D + C V+ + +QSP+IAQGV PEE GAGDQG Sbjct: 66 VERIVRDTVNGIGYHHSDLGFDGETCAVINMLGKQSPEIAQGVD---RADPEEQGAGDQG 122 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYA++ET LMP Sbjct: 123 LMFGYASNETEVLMPAPIEYAHRLMERQSELRRAGELPWLRPDAKAQITLKYDGSKPVAI 182 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IK V+PA+ L T +H+NP+G+FVIGGP GDAG Sbjct: 183 DAVVLSTQHDPSISQADLQEAIMESIIKQVLPAELLHAGTRYHINPTGKFVIGGPVGDAG 242 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY R AK+I+A+G+A RC VQ+SY Sbjct: 243 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAVRYVAKNIVAAGIADRCEVQVSY 302 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ ++++GT KI + EI++L++ +FD RP I+ L+L + + +TA++G Sbjct: 303 AIGVAEPTSISINTFGTNKISNDEIIRLIRTHFDLRPYGITRMLNLLQ--PMYQQTASFG 360 Query: 1025 HFGRDDAD--FTWEVVKPLKFDKASA 1096 HFGR ++ FTWE + + KA A Sbjct: 361 HFGRQGSETAFTWEKIDKAEILKADA 386
>Q2A1N2:METK_FRATH S-adenosylmethionine synthetase - Francisella tularensis subsp.| holarctica (strain LVS) Length = 386 Score = 307 bits (787), Expect = 6e-83 Identities = 176/386 (45%), Positives = 231/386 (59%), Gaps = 54/386 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 ++ +LFTSESV+EGHPDKL DQ+SDA+LD L QD +++VACET+ KT M +V GEITT Sbjct: 2 SKNYLFTSESVSEGHPDKLADQISDAILDEILKQDKNARVACETLVKTGMALVAGEITTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VD E++VR+ G+ + G+D C V+ I +QS DIAQGV E++GA Sbjct: 62 AWVDIEELVRNVITETGYDNASKGIDGRTCSVINAIGKQSRDIAQGVDRGSL---EDLGA 118 Query: 455 GDQGIMFGYATDETPELMP----LSHVLATKLGARLK----------------------- 553 GDQG+MFG+AT+ETP LMP SH+L K K Sbjct: 119 GDQGLMFGFATNETPTLMPSAIYYSHLLMRKQAELRKSGKLAWLRPDAKAQVTLAYENDK 178 Query: 554 ---------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 E ++K VIP + + ++T +H+NP+G F+IGGP Sbjct: 179 PKFIDTIVLSTQHNESISQKELHDAVIEEIVKKVIPNELITKDTKYHINPTGVFLIGGPQ 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRSGAY+ R AK+I+A+GLA +C V Sbjct: 239 GDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSGAYMGRYIAKNIVAAGLADKCEV 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q++YAIGV +P+S+ V+++GTGKI D +I KLV E FD R G I NLDL + R KT Sbjct: 299 QVAYAIGVAKPVSLMVNTFGTGKITDNQIEKLVAEVFDLRVGKIIENLDLLRPIYR--KT 356 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKA 1090 + YGHFGR+ +FTWE K DKA Sbjct: 357 SNYGHFGRELPEFTWE-----KIDKA 377
>Q31EL0:METK_THICR S-adenosylmethionine synthetase - Thiomicrospira crunogena (strain| XCL-2) Length = 385 Score = 307 bits (786), Expect = 8e-83 Identities = 178/393 (45%), Positives = 231/393 (58%), Gaps = 54/393 (13%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 T +FTSESV+EGHPDK+ DQ+SDA+LDA + QD ++VACET KT MVM+ GEITT A Sbjct: 3 TTVFTSESVSEGHPDKIADQISDAMLDAIMKQDPKARVACETFVKTGMVMLGGEITTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 VD E++VR +IG+ D+G D + C VL +I +QSP+IAQGV + E GAGD Sbjct: 63 VDQEELVRQVVNDIGYNHGDLGFDGETCAVLSSIGKQSPEIAQGVDEY---EDHEQGAGD 119 Query: 461 QGIMFGYATDETPELMP----LSHVLATK------------------------------- 535 QG+MFGYA++ET LMP +H L K Sbjct: 120 QGLMFGYASNETDVLMPAPIYFAHRLMEKQAELRKAGKLDWLRPDAKSQVTLRYEDGQPV 179 Query: 536 -------------------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGD 658 L + E +IKPV+P +L T +H+NP+GRFVIGGP GD Sbjct: 180 AVDAVVLSTQHSPEVDNKDLHEAVMEEIIKPVLPEGWLHSGTQYHINPTGRFVIGGPVGD 239 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 AGLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA +C +Q+ Sbjct: 240 AGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLADKCEIQV 299 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAA 1018 SYAIGV P S+ ++++GT K+ I KLV+E+FD RP + LDL + + KTA+ Sbjct: 300 SYAIGVAAPTSISIETFGTEKVAVSLIEKLVREHFDLRPKGLIAMLDLYR--PIYQKTAS 357 Query: 1019 YGHFGRDDADFTWEVVKPLKFDKASA*EQDITL 1117 YGHFGR+ +FTWE K DKA+A D L Sbjct: 358 YGHFGRELPEFTWE-----KTDKAAALRADAGL 385
>Q1QCH2:METK_PSYCK S-adenosylmethionine synthetase - Psychrobacter cryohalolentis| (strain K5) Length = 388 Score = 307 bits (786), Expect = 8e-83 Identities = 174/386 (45%), Positives = 232/386 (60%), Gaps = 56/386 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDA+LDA L QD ++VACET+ KT V++ GEITT A +D Sbjct: 6 LFTSESVSEGHPDKMADQISDAILDAILRQDLHARVACETLVKTGAVVLAGEITTTANID 65 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E+IVRDT IG+ D+G D + C V+ + +QSP+IAQGV PEE GAGDQG Sbjct: 66 VERIVRDTVNGIGYHHSDLGFDGETCAVINMLGKQSPEIAQGVD---RADPEEQGAGDQG 122 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYA++ET LMP Sbjct: 123 LMFGYASNETEVLMPAPIEYAHRLMERQSELRRAGELPWLRPDAKAQVTLKYDGNKPVAI 182 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IK V+PA+ L T +H+NP+G+FVIGGP GDAG Sbjct: 183 DAVVLSTQHDPSISQADLQEAIMESIIKQVLPAELLHAGTRYHINPTGKFVIGGPVGDAG 242 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY R AK+I+A+G+A RC VQ+SY Sbjct: 243 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAVRYVAKNIVAAGIADRCEVQVSY 302 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ ++++GT KI + EI+ L++ +FD RP I+ L+L + + +TA++G Sbjct: 303 AIGVAEPTSISINTFGTNKISNDEIISLIRTHFDLRPYGITRMLNLLQ--PMYQQTASFG 360 Query: 1025 HFGRDDAD--FTWEVVKPLKFDKASA 1096 HFGR ++ FTWE K KA A Sbjct: 361 HFGRQGSETAFTWEKTDKAKILKADA 386
>Q6AQ43:METK_DESPS S-adenosylmethionine synthetase - Desulfotalea psychrophila| Length = 398 Score = 307 bits (786), Expect = 8e-83 Identities = 172/396 (43%), Positives = 236/396 (59%), Gaps = 54/396 (13%) Frame = +2 Query: 71 ITSTKEMAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVM 250 I + + + +LFTSESV+EGHPDK+ DQ+SDA+LDA L QD ++VACET+ T M + Sbjct: 4 ICNKRRLFMSNYLFTSESVSEGHPDKVADQISDAILDAILEQDPQARVACETLVTTGMAL 63 Query: 251 VLGEITTKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFT 430 + GEITT A VD ++VR+T + IG+ S ++G D C V+ I++QSPDIAQGV+ Sbjct: 64 IAGEITTSAWVDMPEVVRNTIKEIGYNSSEMGFDWQSCAVMTTIDKQSPDIAQGVNEGAG 123 Query: 431 KRPEEVGAGDQGIMFGYATDETPELMP----LSH-------------------------- 520 ++ GAGDQG+MFGYA++ET LMP L+H Sbjct: 124 IDLDQ-GAGDQGLMFGYASNETDVLMPMPITLAHRLTRRQAQVRKSSILPWLRPDAKSQV 182 Query: 521 ---------------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSG 628 VL+T+ L + E +IKP +PA +D NT F +NP+G Sbjct: 183 TIEYENKIPKRIDAVVLSTQHDESISYNDLKEAVMEEIIKPTLPADMIDANTKFFINPTG 242 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFVIGGP GD GLTGRKII+DTY KDP+KVDRS AY R AK+++A+ Sbjct: 243 RFVIGGPVGDCGLTGRKIIVDTYGGKALHGGGAFSGKDPSKVDRSSAYYGRYVAKNLVAA 302 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 G+A +Q++YAIG+ +P+S+ V+S+GTG+I D I +L+ NFD RP I LDL + Sbjct: 303 GIASELQIQVAYAIGIAQPVSINVNSFGTGRISDAAIKELILGNFDLRPKAIVQQLDLLR 362 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 R +TAAYGHFGR D +F WE ++ K++A Sbjct: 363 PIYR--QTAAYGHFGRSDVEFPWERTDKIEELKSAA 396
>Q7VUL5:METK_BORPE S-adenosylmethionine synthetase - Bordetella pertussis| Length = 387 Score = 306 bits (785), Expect = 1e-82 Identities = 180/393 (45%), Positives = 232/393 (59%), Gaps = 54/393 (13%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MA FLFTSESV+EGHPDK+ DQ+SDA+LDA QD +++VA ET+ T +V++ GEIT Sbjct: 1 MANNDFLFTSESVSEGHPDKVADQISDAILDAIFTQDPNARVAAETLCNTGLVVLAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV 448 T A VDY ++ RDT R+IG+ + + G+D C VLV ++QSPDIAQGV + Sbjct: 61 TTANVDYIQVARDTIRHIGYDNTEYGIDYKGCAVLVAYDKQSPDIAQGVDRSSEDYLNQ- 119 Query: 449 GAGDQGIMFGYATDET---------------------------PELMPLSH--------- 520 GAGDQG+MFGYA DET P L P + Sbjct: 120 GAGDQGLMFGYACDETPDLMPAPIWYAHRLVQRQSELRKDGRLPWLRPDAKSQVTFRYVD 179 Query: 521 ---------VLATKLGARLK---------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGG 646 VL+T+ + E +IKP P + T F +NP+GRFVIGG Sbjct: 180 GRPAEVDTVVLSTQHSPEISQASIREAVIEDIIKPSFPEGLITPKTKFLVNPTGRFVIGG 239 Query: 647 PHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRC 826 P GD GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLAR+C Sbjct: 240 PQGDCGLTGRKIIVDTYGGACPHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLARQC 299 Query: 827 IVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFI 1006 VQ+SYAIGV EP+++ V + GTG IPD +I KLV+E+FD RP I LDL + + Sbjct: 300 QVQVSYAIGVAEPINITVYTEGTGVIPDEQIAKLVREHFDLRPKGIVNMLDLLR--PIYT 357 Query: 1007 KTAAYGHFGRDDADFTWEVVKPLKFDKASA*EQ 1105 KTAAYGHFGR + +F+WE DKA+A +Q Sbjct: 358 KTAAYGHFGRSEPEFSWEAT-----DKAAALKQ 385
>Q7W200:METK_BORPA S-adenosylmethionine synthetase - Bordetella parapertussis| Length = 387 Score = 306 bits (785), Expect = 1e-82 Identities = 180/393 (45%), Positives = 232/393 (59%), Gaps = 54/393 (13%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MA FLFTSESV+EGHPDK+ DQ+SDA+LDA QD +++VA ET+ T +V++ GEIT Sbjct: 1 MANNDFLFTSESVSEGHPDKVADQISDAILDAIFTQDPNARVAAETLCNTGLVVLAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV 448 T A VDY ++ RDT R+IG+ + + G+D C VLV ++QSPDIAQGV + Sbjct: 61 TTANVDYIQVARDTIRHIGYDNTEYGIDYKGCAVLVAYDKQSPDIAQGVDRSSEDYLNQ- 119 Query: 449 GAGDQGIMFGYATDET---------------------------PELMPLSH--------- 520 GAGDQG+MFGYA DET P L P + Sbjct: 120 GAGDQGLMFGYACDETPDLMPAPIWYAHRLVQRQSELRKDGRLPWLRPDAKSQVTFRYVD 179 Query: 521 ---------VLATKLGARLK---------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGG 646 VL+T+ + E +IKP P + T F +NP+GRFVIGG Sbjct: 180 GRPAEVDTVVLSTQHSPEISQASIREAVIEDIIKPSFPEGLITPKTKFLVNPTGRFVIGG 239 Query: 647 PHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRC 826 P GD GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLAR+C Sbjct: 240 PQGDCGLTGRKIIVDTYGGACPHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLARQC 299 Query: 827 IVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFI 1006 VQ+SYAIGV EP+++ V + GTG IPD +I KLV+E+FD RP I LDL + + Sbjct: 300 QVQVSYAIGVAEPINITVYTEGTGVIPDEQIAKLVREHFDLRPKGIVNMLDLLR--PIYT 357 Query: 1007 KTAAYGHFGRDDADFTWEVVKPLKFDKASA*EQ 1105 KTAAYGHFGR + +F+WE DKA+A +Q Sbjct: 358 KTAAYGHFGRSEPEFSWEAT-----DKAAALKQ 385
>Q7WQX8:METK_BORBR S-adenosylmethionine synthetase - Bordetella bronchiseptica| (Alcaligenes bronchisepticus) Length = 387 Score = 306 bits (785), Expect = 1e-82 Identities = 180/393 (45%), Positives = 232/393 (59%), Gaps = 54/393 (13%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MA FLFTSESV+EGHPDK+ DQ+SDA+LDA QD +++VA ET+ T +V++ GEIT Sbjct: 1 MANNDFLFTSESVSEGHPDKVADQISDAILDAIFTQDPNARVAAETLCNTGLVVLAGEIT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV 448 T A VDY ++ RDT R+IG+ + + G+D C VLV ++QSPDIAQGV + Sbjct: 61 TTANVDYIQVARDTIRHIGYDNTEYGIDYKGCAVLVAYDKQSPDIAQGVDRSSEDYLNQ- 119 Query: 449 GAGDQGIMFGYATDET---------------------------PELMPLSH--------- 520 GAGDQG+MFGYA DET P L P + Sbjct: 120 GAGDQGLMFGYACDETPDLMPAPIWYAHRLVQRQSELRKDGRLPWLRPDAKSQVTFRYVD 179 Query: 521 ---------VLATKLGARLK---------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGG 646 VL+T+ + E +IKP P + T F +NP+GRFVIGG Sbjct: 180 GRPAEVDTVVLSTQHSPEISQASIREAVIEDIIKPSFPEGLITPKTKFLVNPTGRFVIGG 239 Query: 647 PHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRC 826 P GD GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLAR+C Sbjct: 240 PQGDCGLTGRKIIVDTYGGACPHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLARQC 299 Query: 827 IVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFI 1006 VQ+SYAIGV EP+++ V + GTG IPD +I KLV+E+FD RP I LDL + + Sbjct: 300 QVQVSYAIGVAEPINITVYTEGTGVIPDEQIAKLVREHFDLRPKGIVNMLDLLR--PIYT 357 Query: 1007 KTAAYGHFGRDDADFTWEVVKPLKFDKASA*EQ 1105 KTAAYGHFGR + +F+WE DKA+A +Q Sbjct: 358 KTAAYGHFGRSEPEFSWEAT-----DKAAALKQ 385
>Q5R5H1:METK2_PONPY S-adenosylmethionine synthetase isoform type-2 - Pongo pygmaeus| (Orangutan) Length = 395 Score = 306 bits (785), Expect = 1e-82 Identities = 178/383 (46%), Positives = 223/383 (58%), Gaps = 56/383 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 TFLFTSESV EGHPDK+CDQ+SDAVLDA L QD D+KVACETV KT M+++ GEIT++A Sbjct: 17 TFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAA 76 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLV-------------NIEQQSPDIAQG--- 412 VDY+K+VR+ ++IG+ G D C VLV ++++ DI G Sbjct: 77 VDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQG 136 Query: 413 -VHGHFTKRPEEVGA----------------------------GDQGIMFGYATDETPEL 505 + G+ T EE + Y D L Sbjct: 137 LMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVL 196 Query: 506 MPLSHVLAT-----------KLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 H + ++ LKE VIK V+PAKYLDE+TI+HL PSGRFVIGGP Sbjct: 197 PIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQ 256 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GDAGLTGRKII+DTY KD TKVDRS AY AR AKS++ GL RR +V Sbjct: 257 GDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLV 316 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV PLS+ + YGT + +RE+L++VK+NFD RPG+I +LDLKK + +T Sbjct: 317 QVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKK--PIYQRT 374 Query: 1013 AAYGHFGRDDADFTWEVVKPLKF 1081 AAYGHFGRD F WEV K LK+ Sbjct: 375 AAYGHFGRD--SFPWEVPKKLKY 395
>Q4R924:METK2_MACFA S-adenosylmethionine synthetase isoform type-2 - Macaca fascicularis| (Crab eating macaque) (Cynomolgus monkey) Length = 395 Score = 306 bits (785), Expect = 1e-82 Identities = 178/383 (46%), Positives = 223/383 (58%), Gaps = 56/383 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 TFLFTSESV EGHPDK+CDQ+SDAVLDA L QD D+KVACETV KT M+++ GEIT++A Sbjct: 17 TFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAA 76 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLV-------------NIEQQSPDIAQG--- 412 VDY+K+VR+ ++IG+ G D C VLV ++++ DI G Sbjct: 77 VDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQG 136 Query: 413 -VHGHFTKRPEEVGA----------------------------GDQGIMFGYATDETPEL 505 + G+ T EE + Y D L Sbjct: 137 LMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVL 196 Query: 506 MPLSHVLAT-----------KLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 H + ++ LKE VIK V+PAKYLDE+TI+HL PSGRFVIGGP Sbjct: 197 PIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQ 256 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GDAGLTGRKII+DTY KD TKVDRS AY AR AKS++ GL RR +V Sbjct: 257 GDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLV 316 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV PLS+ + YGT + +RE+L++VK+NFD RPG+I +LDLKK + +T Sbjct: 317 QVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKK--PIYQRT 374 Query: 1013 AAYGHFGRDDADFTWEVVKPLKF 1081 AAYGHFGRD F WEV K LK+ Sbjct: 375 AAYGHFGRD--SFPWEVPKKLKY 395
>P31153:METK2_HUMAN S-adenosylmethionine synthetase isoform type-2 - Homo sapiens (Human)| Length = 395 Score = 306 bits (785), Expect = 1e-82 Identities = 178/383 (46%), Positives = 223/383 (58%), Gaps = 56/383 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 TFLFTSESV EGHPDK+CDQ+SDAVLDA L QD D+KVACETV KT M+++ GEIT++A Sbjct: 17 TFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAA 76 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLV-------------NIEQQSPDIAQG--- 412 VDY+K+VR+ ++IG+ G D C VLV ++++ DI G Sbjct: 77 VDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQG 136 Query: 413 -VHGHFTKRPEEVGA----------------------------GDQGIMFGYATDETPEL 505 + G+ T EE + Y D L Sbjct: 137 LMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVL 196 Query: 506 MPLSHVLAT-----------KLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 H + ++ LKE VIK V+PAKYLDE+TI+HL PSGRFVIGGP Sbjct: 197 PIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQ 256 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GDAGLTGRKII+DTY KD TKVDRS AY AR AKS++ GL RR +V Sbjct: 257 GDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLV 316 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV PLS+ + YGT + +RE+L++VK+NFD RPG+I +LDLKK + +T Sbjct: 317 QVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKK--PIYQRT 374 Query: 1013 AAYGHFGRDDADFTWEVVKPLKF 1081 AAYGHFGRD F WEV K LK+ Sbjct: 375 AAYGHFGRD--SFPWEVPKKLKY 395
>Q6F1M6:METK_MESFL S-adenosylmethionine synthetase - Mesoplasma florum (Acholeplasma| florum) Length = 377 Score = 306 bits (784), Expect = 1e-82 Identities = 177/378 (46%), Positives = 230/378 (60%), Gaps = 54/378 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+CDQ+SDA+LD L QD ++KVACET TN +++ G+ITT A+VD Sbjct: 4 LFTSESVSEGHPDKICDQISDAILDEVLKQDPNAKVACETFATTNYLLIGGQITTTASVD 63 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 YEKI RD R IG+ +D G++AD CK+ + +EQQS DIA G+ E +GAGDQG Sbjct: 64 YEKIARDVLRKIGYNNDAYGINADTCKIDIRVEQQSADIALGID----LDTEVIGAGDQG 119 Query: 467 IMFGYATDETPELMPL----SH---VLATKLGARLKEHVIKPVIPAK----YLDE----- 598 IMFGYAT+E+ +PL SH LA+KL K +P + ++ Y DE Sbjct: 120 IMFGYATNESKTFLPLAITISHELVYLASKLRKEGKFKWARPDMKSQVTIDYTDESNPKI 179 Query: 599 ------------------------------------NTIFH--LNPSGRFVIGGPHGDAG 664 NT F+ +NP+GRFVIGGP GD G Sbjct: 180 DTILMSIQHDDEMIEEEFKKFIKSEIMDVVAKEFELNTDFNVLINPTGRFVIGGPQGDTG 239 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KD TKVDRS AY+AR AAK+++ASGLA + +Q+SY Sbjct: 240 LTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSAAYMARYAAKNLVASGLADKIEIQVSY 299 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIG PEP+S+F++++GT K+ I K + ENFDF I LDL+K F+KTA YG Sbjct: 300 AIGKPEPVSIFIETFGTEKVSKEVIAKALNENFDFSVNEIIKKLDLRK--PTFLKTATYG 357 Query: 1025 HFGRDDADFTWEVVKPLK 1078 HFG+D +FTWE + +K Sbjct: 358 HFGKD--EFTWEQLDKVK 373
>Q3THS6:METK2_MOUSE S-adenosylmethionine synthetase isoform type-2 - Mus musculus (Mouse)| Length = 395 Score = 306 bits (784), Expect = 1e-82 Identities = 177/383 (46%), Positives = 223/383 (58%), Gaps = 56/383 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 TFLFTSESV EGHPDK+CDQ+SDAVLDA L QD D+KVACETV KT M+++ GEIT++A Sbjct: 17 TFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAA 76 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLV-------------NIEQQSPDIAQG--- 412 +DY+K+VR+ ++IG+ G D C VLV ++++ DI G Sbjct: 77 IDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQG 136 Query: 413 -VHGHFTKRPEEVGA----------------------------GDQGIMFGYATDETPEL 505 + G+ T EE + Y D L Sbjct: 137 LMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVL 196 Query: 506 MPLSHVLAT-----------KLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 H + ++ LKE VIK V+PAKYLDE+TI+HL PSGRFVIGGP Sbjct: 197 PIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQ 256 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GDAGLTGRKII+DTY KD TKVDRS AY AR AKS++ GL RR +V Sbjct: 257 GDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLV 316 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV PLS+ + YGT + +RE+L++VK+NFD RPG+I +LDLKK + +T Sbjct: 317 QVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKK--PIYQRT 374 Query: 1013 AAYGHFGRDDADFTWEVVKPLKF 1081 AAYGHFGRD F WEV K LK+ Sbjct: 375 AAYGHFGRD--SFPWEVPKKLKY 395
>Q5NIC7:METK_FRATT S-adenosylmethionine synthetase - Francisella tularensis subsp.| tularensis Length = 386 Score = 306 bits (783), Expect = 2e-82 Identities = 175/386 (45%), Positives = 230/386 (59%), Gaps = 54/386 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 ++ +LFTSESV+EGHPDKL DQ+SDA+LD L QD +++VACET+ KT M +V GEITT Sbjct: 2 SKNYLFTSESVSEGHPDKLADQISDAILDEILKQDKNARVACETLVKTGMALVAGEITTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VD E++VR+ G+ + G+D C V+ I +QS DI QGV E++GA Sbjct: 62 AWVDIEELVRNVITETGYDNASKGIDGRTCSVINAIGKQSRDITQGVDRGSL---EDLGA 118 Query: 455 GDQGIMFGYATDETPELMP----LSHVLATKLGARLK----------------------- 553 GDQG+MFG+AT+ETP LMP SH+L K K Sbjct: 119 GDQGLMFGFATNETPTLMPSAIYYSHLLMRKQAELRKSGKLAWLRPDAKAQVTLAYENDK 178 Query: 554 ---------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 E ++K VIP + + ++T +H+NP+G F+IGGP Sbjct: 179 PKFIDTIVLSTQHNESISQKELHDAVIEEIVKKVIPNELITKDTKYHINPTGVFLIGGPQ 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRSGAY+ R AK+I+A+GLA +C V Sbjct: 239 GDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSGAYMGRYIAKNIVAAGLADKCEV 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q++YAIGV +P+S+ V+++GTGKI D +I KLV E FD R G I NLDL + R KT Sbjct: 299 QVAYAIGVAKPVSLMVNTFGTGKITDNQIEKLVAEVFDLRVGKIIENLDLLRPIYR--KT 356 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKA 1090 + YGHFGR+ +FTWE K DKA Sbjct: 357 SNYGHFGRELPEFTWE-----KIDKA 377
>Q97F85:METK_CLOAB S-adenosylmethionine synthetase - Clostridium acetobutylicum| Length = 391 Score = 306 bits (783), Expect = 2e-82 Identities = 171/378 (45%), Positives = 226/378 (59%), Gaps = 60/378 (15%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+CDQ+SDA+LDA L +D + +VACET T +V V+GEI+T VD Sbjct: 4 LFTSESVTEGHPDKICDQISDAILDAILEKDPNGRVACETTVTTGIVNVMGEISTNCYVD 63 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE------V 448 KIVR T R IG+ G D D C V+ +I++QS DIA GV + E V Sbjct: 64 IPKIVRKTVREIGYTRAKYGFDCDTCAVVTSIDEQSADIAMGVDEALESKKGEMDKIDAV 123 Query: 449 GAGDQGIMFGYATDETPELMP----LSHVLATKLGARLK--------------------- 553 GAGDQG+MFGYAT+ET E MP L+H L+ +L K Sbjct: 124 GAGDQGMMFGYATNETKEFMPMPIALAHRLSRRLAEVRKDGTLDYLRPDGKTQVTIEYED 183 Query: 554 -----------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGG 646 E V+K VI + LDENT +++NP+GRFV+GG Sbjct: 184 DKPVRVDAIVISTQHGPEIGHEQIEKDLIEKVVKYVISPELLDENTKYYINPTGRFVVGG 243 Query: 647 PHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRC 826 P GD+GLTGRKII+DTY KDPTKVDRS AY AR AK+++A+G+A + Sbjct: 244 PQGDSGLTGRKIIVDTYGGYGRHGGGAFSGKDPTKVDRSAAYAARWVAKNLVAAGIADKL 303 Query: 827 IVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFI 1006 +Q++YAIGV +P+S+ VD++GTGKI + +I+++V++ FD RPG I +L+LK+ R Sbjct: 304 EIQLAYAIGVAKPVSISVDTFGTGKIEESKIVEIVEKVFDLRPGAIIRDLNLKRPIYR-- 361 Query: 1007 KTAAYGHFGRDDADFTWE 1060 + AAYGHFGR D + WE Sbjct: 362 QVAAYGHFGRLDVELPWE 379
>Q3K5E8:METK_PSEPF S-adenosylmethionine synthetase - Pseudomonas fluorescens (strain| PfO-1) Length = 396 Score = 305 bits (782), Expect = 2e-82 Identities = 181/398 (45%), Positives = 237/398 (59%), Gaps = 64/398 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDAVLDA +AQD ++VA ET+ KT + +V GE+TT Sbjct: 2 SEYSLFTSESVSEGHPDKIADQISDAVLDAIIAQDKHARVAVETLVKTGVAIVAGEVTTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VD E+IVRD +IG+ S DVG D C V+ I +QSPDI QGV +PE+ GA Sbjct: 62 AWVDLEQIVRDVICDIGYTSSDVGFDGATCGVMNIIGKQSPDINQGVD---RAKPEDQGA 118 Query: 455 GDQGIMFGYATDETPELMP----LSH---------------------------------- 520 GDQG+MFGYA++ET LMP SH Sbjct: 119 GDQGLMFGYASNETDVLMPAPITFSHQLVQRQAEARKSGLLPWLRPDAKSQVTCRYEGGK 178 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E ++K V+PA+ L ++T FH+NP+G+F+IGGP Sbjct: 179 VVGIDAVVLSTQHNPEVSYNDLREGVMELIVKHVLPAELLSKDTQFHINPTGQFIIGGPV 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+D+Y KDP+KVDRS AY R AK+I+A+GLA RC + Sbjct: 239 GDCGLTGRKIIVDSYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAERCEI 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV +P S+ ++++GTGKI D +I+KLV+E FD RP I+ LDL + +T Sbjct: 299 QVSYAIGVAQPTSISLNTFGTGKISDDKIIKLVREVFDLRPYAITTMLDLLH--PMYQET 356 Query: 1013 AAYGHFGRDD----------ADFTWEVVKPLKFDKASA 1096 AAYGHFGR + FTWE K D+A A Sbjct: 357 AAYGHFGRAPQTKTVGEDTFSTFTWE-----KTDRADA 389
>Q4K4I7:METK_PSEF5 S-adenosylmethionine synthetase - Pseudomonas fluorescens (strain| Pf-5 / ATCC BAA-477) Length = 396 Score = 305 bits (782), Expect = 2e-82 Identities = 179/386 (46%), Positives = 233/386 (60%), Gaps = 64/386 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDAVLDA +AQD ++VA ET+ KT + +V GE+TT Sbjct: 2 SEYSLFTSESVSEGHPDKIADQISDAVLDAIIAQDKHARVAVETLVKTGVAIVAGEVTTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VD E+IVRD +IG+ S DVG D C V+ I +QSPDI QGV +PE+ GA Sbjct: 62 AWVDLEQIVRDVICDIGYTSSDVGFDGATCGVMNIIGKQSPDINQGVD---RAKPEDQGA 118 Query: 455 GDQGIMFGYATDETPELMP----LSH---------------------------------- 520 GDQG+MFGYA++ET LMP SH Sbjct: 119 GDQGLMFGYASNETEVLMPAPITFSHQLVQRQAEARKSGLLPWLRPDAKSQVTCRYEGGK 178 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E ++K V+PA+ L ++T FH+NP+G+F+IGGP Sbjct: 179 VVGIDAVVLSTQHNPEVSYSDLREGVMELIVKHVLPAELLSKDTQFHINPTGQFIIGGPV 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+D+Y KDP+KVDRS AY R AK+I+A+GLA RC + Sbjct: 239 GDCGLTGRKIIVDSYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAERCEI 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV +P S+ ++++GTGKI D +I+KLV+E FD RP I+ LDL + +T Sbjct: 299 QVSYAIGVAQPTSISLNTFGTGKISDDKIIKLVREVFDLRPYAITTMLDLLH--PMYQET 356 Query: 1013 AAYGHFGR--------DD--ADFTWE 1060 AAYGHFGR DD FTWE Sbjct: 357 AAYGHFGRAPQTKTVGDDTFTTFTWE 382
>Q48CH3:METK_PSE14 S-adenosylmethionine synthetase - Pseudomonas syringae pv.| phaseolicola (strain 1448A / Race 6) Length = 396 Score = 305 bits (782), Expect = 2e-82 Identities = 179/398 (44%), Positives = 236/398 (59%), Gaps = 64/398 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDAVLDA +A+D ++VACET+ KT + ++ GE++T Sbjct: 2 SEYSLFTSESVSEGHPDKIADQISDAVLDAIIAEDKYARVACETLVKTGVAIIAGEVSTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VD E IVR+ +IG+ S DVG D C V+ I +QS DIAQGV +PE+ GA Sbjct: 62 AWVDLEDIVRNVILDIGYNSSDVGFDGATCGVMNIIGKQSVDIAQGVD---RSKPEDQGA 118 Query: 455 GDQGIMFGYATDETPELMP----LSH---------------------------------- 520 GDQG+MFGYA++ET LMP SH Sbjct: 119 GDQGLMFGYASNETDVLMPAPITFSHQLVQRQAEARKSGLLPWLRPDAKSQVTCRYENGK 178 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E ++K VIPA L ++T FH+NP+G F+IGGP Sbjct: 179 VVGVDAIVLSTQHNPDVSYKDLREGVMELIVKHVIPAHLLHKDTQFHINPTGNFIIGGPV 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA RC + Sbjct: 239 GDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAERCEI 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV +P+S+ ++++GTGK+ D +I+KLV++NFD RP I+ LDL + T Sbjct: 299 QVSYAIGVAQPMSISLNTFGTGKLSDDKIIKLVRDNFDLRPYAITTMLDLLH--PMYQAT 356 Query: 1013 AAYGHFGRDDAD----------FTWEVVKPLKFDKASA 1096 AAYGHFGR + FTWE K D+A A Sbjct: 357 AAYGHFGRTPVEMTIGDDTFTAFTWE-----KTDRADA 389
>Q7MHK6:METK_VIBVY S-adenosylmethionine synthetase - Vibrio vulnificus (strain YJ016)| Length = 384 Score = 305 bits (780), Expect = 4e-82 Identities = 174/372 (46%), Positives = 227/372 (61%), Gaps = 54/372 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MVMV GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E++ R+T R IG++ D+G DA+ C VL I +QSPDI QGV P+E GAGDQG Sbjct: 65 IEELTRETVREIGYVHSDMGFDANSCAVLNTIGKQSPDINQGVD---KADPKEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 IMFGYA +ET LMP Sbjct: 122 IMFGYACNETEVLMPAPITYAHRLMERQAKVRKDGTLPWLRPDAKSQVTFQYEQGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKPV+P+++L++ T + +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHCDSISTPDLREAVMEEIIKPVLPSEWLNKETKYFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+G+A RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGMADRCEIQLSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV +P S+ V+++GT K+ I++ V++ FD RP + L+L + + KTAAYG Sbjct: 302 AIGVADPTSIMVETFGTEKVSHDIIIEAVRQFFDLRPYGLQEMLNLLQ--PIYKKTAAYG 359 Query: 1025 HFGRDDADFTWE 1060 HFGR+ +F WE Sbjct: 360 HFGRE--EFPWE 369
>Q8DCA3:METK_VIBVU S-adenosylmethionine synthetase - Vibrio vulnificus| Length = 384 Score = 305 bits (780), Expect = 4e-82 Identities = 174/372 (46%), Positives = 227/372 (61%), Gaps = 54/372 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET KT MVMV GEITT A VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E++ R+T R IG++ D+G DA+ C VL I +QSPDI QGV P+E GAGDQG Sbjct: 65 IEELTRETVREIGYVHSDMGFDANSCAVLNTIGKQSPDINQGVD---KADPKEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 IMFGYA +ET LMP Sbjct: 122 IMFGYACNETEVLMPAPITYAHRLMERQAKVRKDGTLPWLRPDAKSQVTFQYEQGKIVGI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKPV+P+++L++ T + +NP+GRFVIGGP GD G Sbjct: 182 DAVVLSTQHCDSISTPDLREAVMEEIIKPVLPSEWLNKETKYFINPTGRFVIGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+I+A+G+A RC +Q+SY Sbjct: 242 LTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGMADRCEIQLSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV +P S+ V+++GT K+ I++ V++ FD RP + L+L + + KTAAYG Sbjct: 302 AIGVADPTSIMVETFGTEKVSHDIIIEAVRQFFDLRPYGLQEMLNLLQ--PIYKKTAAYG 359 Query: 1025 HFGRDDADFTWE 1060 HFGR+ +F WE Sbjct: 360 HFGRE--EFPWE 369
>Q8NVZ9:METK_STAAW S-adenosylmethionine synthetase - Staphylococcus aureus (strain MW2)| Length = 397 Score = 305 bits (780), Expect = 4e-82 Identities = 170/380 (44%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LDA L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T + IG+ G D + +L I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 GAGDQG+MFGYAT+ET MP LSH Sbjct: 127 TGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYD 186 Query: 521 --------------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 V ++ +K HVI P +P ++E T F++NP+GRFVI Sbjct: 187 ENDNPVRIDTIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAD 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++GTGK+ + ++++ V+++FD RP I LDLK+ Sbjct: 307 QCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQ--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR D F WE Sbjct: 365 YKQTAAYGHFGRTDVLFPWE 384
>P50307:METK_STAAU S-adenosylmethionine synthetase - Staphylococcus aureus| Length = 397 Score = 305 bits (780), Expect = 4e-82 Identities = 170/380 (44%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LDA L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T + IG+ G D + +L I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 GAGDQG+MFGYAT+ET MP LSH Sbjct: 127 TGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYD 186 Query: 521 --------------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 V ++ +K HVI P +P ++E T F++NP+GRFVI Sbjct: 187 ENDNPVRIDTIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGIARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAD 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++GTGK+ + ++++ V+++FD RP I LDLK+ Sbjct: 307 QCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQ--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR D F WE Sbjct: 365 YKQTAAYGHFGRTDVLFPWE 384
>Q6G8E3:METK_STAAS S-adenosylmethionine synthetase - Staphylococcus aureus (strain| MSSA476) Length = 397 Score = 305 bits (780), Expect = 4e-82 Identities = 170/380 (44%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LDA L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T + IG+ G D + +L I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 GAGDQG+MFGYAT+ET MP LSH Sbjct: 127 TGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYD 186 Query: 521 --------------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 V ++ +K HVI P +P ++E T F++NP+GRFVI Sbjct: 187 ENDNPVRIDTIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAD 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++GTGK+ + ++++ V+++FD RP I LDLK+ Sbjct: 307 QCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQ--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR D F WE Sbjct: 365 YKQTAAYGHFGRTDVLFPWE 384
>Q6GFR6:METK_STAAR S-adenosylmethionine synthetase - Staphylococcus aureus (strain| MRSA252) Length = 397 Score = 305 bits (780), Expect = 4e-82 Identities = 170/380 (44%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LDA L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T + IG+ G D + +L I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 GAGDQG+MFGYAT+ET MP LSH Sbjct: 127 TGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYD 186 Query: 521 --------------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 V ++ +K HVI P +P ++E T F++NP+GRFVI Sbjct: 187 ENDNPVRIDTIVVSTQHADDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAD 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++GTGK+ + ++++ V+++FD RP I LDLK+ Sbjct: 307 QCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQ--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR D F WE Sbjct: 365 YKQTAAYGHFGRTDVLFPWE 384
>P66767:METK_STAAN S-adenosylmethionine synthetase - Staphylococcus aureus (strain N315)| Length = 398 Score = 305 bits (780), Expect = 4e-82 Identities = 170/380 (44%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LDA L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T + IG+ G D + +L I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 GAGDQG+MFGYAT+ET MP LSH Sbjct: 127 TGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYD 186 Query: 521 --------------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 V ++ +K HVI P +P ++E T F++NP+GRFVI Sbjct: 187 ENDNPVRIDTIVVSTQHADDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAD 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++GTGK+ + ++++ V+++FD RP I LDLK+ Sbjct: 307 QCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQ--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR D F WE Sbjct: 365 YKQTAAYGHFGRTDVLFPWE 384
>P66766:METK_STAAM S-adenosylmethionine synthetase - Staphylococcus aureus (strain Mu50| / ATCC 700699) Length = 398 Score = 305 bits (780), Expect = 4e-82 Identities = 170/380 (44%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LDA L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T + IG+ G D + +L I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 GAGDQG+MFGYAT+ET MP LSH Sbjct: 127 TGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYD 186 Query: 521 --------------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 V ++ +K HVI P +P ++E T F++NP+GRFVI Sbjct: 187 ENDNPVRIDTIVVSTQHADDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAD 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++GTGK+ + ++++ V+++FD RP I LDLK+ Sbjct: 307 QCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQ--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR D F WE Sbjct: 365 YKQTAAYGHFGRTDVLFPWE 384
>Q5HEY9:METK_STAAC S-adenosylmethionine synthetase - Staphylococcus aureus (strain COL)| Length = 397 Score = 305 bits (780), Expect = 4e-82 Identities = 170/380 (44%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LDA L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T + IG+ G D + +L I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 GAGDQG+MFGYAT+ET MP LSH Sbjct: 127 TGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYD 186 Query: 521 --------------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 V ++ +K HVI P +P ++E T F++NP+GRFVI Sbjct: 187 ENDNPVRIDTIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAD 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++GTGK+ + ++++ V+++FD RP I LDLK+ Sbjct: 307 QCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQ--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR D F WE Sbjct: 365 YKQTAAYGHFGRTDVLFPWE 384
>Q2YTK1:METK_STAAB S-adenosylmethionine synthetase - Staphylococcus aureus (strain| bovine RF122) Length = 397 Score = 305 bits (780), Expect = 4e-82 Identities = 170/380 (44%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LDA L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T + IG+ G D + +L I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 GAGDQG+MFGYAT+ET MP LSH Sbjct: 127 TGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYD 186 Query: 521 --------------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 V ++ +K HVI P +P ++E T F++NP+GRFVI Sbjct: 187 ENDNPVRIDTIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAD 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++GTGK+ + ++++ V+++FD RP I LDLK+ Sbjct: 307 QCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQ--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR D F WE Sbjct: 365 YKQTAAYGHFGRTDVLFPWE 384
>Q2FFV6:METK_STAA3 S-adenosylmethionine synthetase - Staphylococcus aureus (strain| USA300) Length = 397 Score = 305 bits (780), Expect = 4e-82 Identities = 170/380 (44%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LDA L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T + IG+ G D + +L I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 GAGDQG+MFGYAT+ET MP LSH Sbjct: 127 TGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYD 186 Query: 521 --------------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 V ++ +K HVI P +P ++E T F++NP+GRFVI Sbjct: 187 ENDNPVRIDTIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAD 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++GTGK+ + ++++ V+++FD RP I LDLK+ Sbjct: 307 QCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQ--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR D F WE Sbjct: 365 YKQTAAYGHFGRTDVLFPWE 384
>Q5QVM7:METK_IDILO S-adenosylmethionine synthetase - Idiomarina loihiensis| Length = 381 Score = 305 bits (780), Expect = 4e-82 Identities = 177/389 (45%), Positives = 234/389 (60%), Gaps = 54/389 (13%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLDA LA+D ++VACET KT MV+V GEI+TKA VD Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILAKDPKARVACETYVKTGMVLVGGEISTKAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E + R T ++IG+ D+G D C VL I +QS DI QGV PEE GAGDQG Sbjct: 65 VEDLARQTVKDIGYRHSDMGFDGASCAVLNAIGKQSGDINQGVD---RANPEEQGAGDQG 121 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 +MFGYA++ET LMP Sbjct: 122 LMFGYASNETSVLMPAPITYAHRVMQRQSEVRNNGTLDWLRPDAKSQLTFVYENGKPVAI 181 Query: 515 -SHVLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ L + E +IKPV+P +++ ++T FH+NP+GRFV+GGP GD G Sbjct: 182 DTVVLSTQHREDITQETLREAVMEEIIKPVLPEQWVSKDTQFHINPTGRFVVGGPMGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLA RC +QISY Sbjct: 242 LTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNLVAAGLAERCELQISY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ +D++GT K + +++ LV+ +FD RP + LDL++ + +TAAYG Sbjct: 302 AIGVAEPTSISIDTFGTSKHSEEQLIALVRRHFDLRPYGLIKMLDLER--PIYKQTAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKASA*EQDI 1111 HFGRD + WE + DKA+ + DI Sbjct: 360 HFGRD--NLPWE-----QTDKAADLQADI 381
>Q88AK7:METK_PSESM S-adenosylmethionine synthetase - Pseudomonas syringae pv. tomato| Length = 396 Score = 304 bits (779), Expect = 5e-82 Identities = 179/398 (44%), Positives = 235/398 (59%), Gaps = 64/398 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDAVLDA +A+D ++VACET+ KT + ++ GE++T Sbjct: 2 SEYSLFTSESVSEGHPDKIADQISDAVLDAIIAEDKYARVACETLVKTGVAIIAGEVSTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VD E IVR+ +IG+ S DVG D C V+ I +QS DIAQGV +PE+ GA Sbjct: 62 AWVDLEDIVRNVILDIGYNSSDVGFDGATCGVMNIIGKQSVDIAQGVD---RSKPEDQGA 118 Query: 455 GDQGIMFGYATDETPELMP----LSH---------------------------------- 520 GDQG+MFGYA++ET LMP SH Sbjct: 119 GDQGLMFGYASNETDVLMPAPITFSHQLVQRQAEARKSGLLPWLRPDAKSQVTCRYENGK 178 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E ++K VIPA L ++T FH+NP+G F+IGGP Sbjct: 179 VVGVDAIVLSTQHNPDVSYKDLREGVMELIVKHVIPAHLLHKDTQFHINPTGNFIIGGPV 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA RC + Sbjct: 239 GDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAERCEI 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV +P S+ ++++GTGK+ D +I+KLV++NFD RP I+ LDL + T Sbjct: 299 QVSYAIGVAQPTSISLNTFGTGKLSDDKIIKLVRDNFDLRPYAITTMLDLLH--PMYQAT 356 Query: 1013 AAYGHFGRDDAD----------FTWEVVKPLKFDKASA 1096 AAYGHFGR + FTWE K D+A A Sbjct: 357 AAYGHFGRTPVEMTVGDDTFTAFTWE-----KTDRADA 389
>Q4ZM01:METK_PSEU2 S-adenosylmethionine synthetase - Pseudomonas syringae pv. syringae| (strain B728a) Length = 396 Score = 304 bits (778), Expect = 7e-82 Identities = 181/398 (45%), Positives = 236/398 (59%), Gaps = 64/398 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDAVLDA +A+D ++VACET+ KT + ++ GE++T Sbjct: 2 SEYSLFTSESVSEGHPDKIADQISDAVLDAIIAEDKYARVACETLVKTGVAIIAGEVSTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VD E IVR+ +IG+ S DVG D C V+ I +QS DIAQGV +PE+ GA Sbjct: 62 AWVDLEDIVRNVILDIGYNSSDVGFDGATCGVMNIIGKQSVDIAQGVD---RSKPEDQGA 118 Query: 455 GDQGIMFGYATDETPELMP----LSH---------------------------------- 520 GDQG+MFGYA++ET LMP SH Sbjct: 119 GDQGLMFGYASNETDVLMPAPITFSHQLVQRQAEARKSGLLPWLRPDAKSQVTCRYENGK 178 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E ++K VIPA L ++T FH+NP+G F+IGGP Sbjct: 179 VVGVDAIVLSTQHNPDVSYKDLREGVMELIVKHVIPAHLLHKDTQFHINPTGNFIIGGPV 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA RC + Sbjct: 239 GDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAERCEI 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV +P S+ ++++GTGK+ D +I+KLV++NFD RP I+ LDL + T Sbjct: 299 QVSYAIGVAQPTSISLNTFGTGKLSDDKIIKLVRDNFDLRPYAITTMLDLLH--PMYQAT 356 Query: 1013 AAYGHFGR--------DD--ADFTWEVVKPLKFDKASA 1096 AAYGHFGR DD FTWE K D+A A Sbjct: 357 AAYGHFGRIPVEMTVGDDTFTAFTWE-----KTDRADA 389
>Q5X3N0:METK_LEGPA S-adenosylmethionine synthetase - Legionella pneumophila (strain| Paris) Length = 382 Score = 304 bits (778), Expect = 7e-82 Identities = 173/375 (46%), Positives = 226/375 (60%), Gaps = 54/375 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E ++FTSESV+EGHPDK+ DQ+SDA+LDA LAQD ++VACE + KT MV+V GEITTKA Sbjct: 3 EVYVFTSESVSEGHPDKIADQISDAILDAILAQDPKARVACEVLVKTGMVLVGGEITTKA 62 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 VD E+I R ++IG+ S +G D + C VL I +QSPDIAQGV TK +GAG Sbjct: 63 WVDVEEITRHVIKDIGYNSSQMGFDWESCAVLSAIGKQSPDIAQGVDNQQTKI---LGAG 119 Query: 458 DQGIMFGYATDETPELMPL----SHVLATKLGAR-------------------------- 547 DQG+MFGYA+ ET MP +H L KL Sbjct: 120 DQGLMFGYASRETDVFMPAPIAYAHRLMEKLAKARKSGQLPWLRPDAKCQLTLKYEQGMP 179 Query: 548 ------------------------LKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 ++E +IK V+PA++L++ T + +NP+GRFVIGGP G Sbjct: 180 VEVDTVVFSTQHSPDIEHKDLVEAIREEIIKSVLPAEWLNDKTRYFINPTGRFVIGGPLG 239 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA +C +Q Sbjct: 240 DCGLTGRKIIVDTYGGMARHGGGCFSGKDPSKVDRSAAYAARHVAKNIVAAGLADKCELQ 299 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 ISYAIGV EP S+FVD++GTG++ + EI+ L+ +FD P I DL + R +TA Sbjct: 300 ISYAIGVAEPTSIFVDTFGTGRLKNSEIIDLIHTHFDLTPQGIIDQHDLLRPIYR--QTA 357 Query: 1016 AYGHFGRDDADFTWE 1060 YGH+GR+ +F WE Sbjct: 358 TYGHYGRE--NFPWE 370
>P57486:METK_BUCAI S-adenosylmethionine synthetase - Buchnera aphidicola subsp.| Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) Length = 378 Score = 304 bits (778), Expect = 7e-82 Identities = 170/373 (45%), Positives = 224/373 (60%), Gaps = 54/373 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQ+SDA+LD L QD ++VACET KT MV++ GEITT A V Sbjct: 4 YLFTSESVSEGHPDKIADQISDALLDEILKQDLKARVACETYVKTGMVLIGGEITTTAWV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 D E+I R T +IG+++ D G DA+ C VL I +QSPDI QG++ P + GAGDQ Sbjct: 64 DVEEITRKTINDIGYVNSDAGFDANSCAVLSAIGKQSPDINQGINRF---DPLKQGAGDQ 120 Query: 464 GIMFGYATDETPELMPL----SHVLATK-------------------------------- 535 GI+FGYAT+ET MP +H+L K Sbjct: 121 GIIFGYATNETEFFMPAPITYAHLLMQKQSELRKKNILPWLRPDAKSQVTFKYNNGNIIA 180 Query: 536 ------------------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDA 661 L + + +IKPV+P K+L +NT F +NP+GRFVIGGP GD Sbjct: 181 IDTVVLSTQHQENITQKYLKEAVMDEIIKPVLPDKWLTKNTKFFINPTGRFVIGGPMGDC 240 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 G+TGRKII+DTY KDP+KVDRS AY AR AK+I+ASGLA RC +Q+S Sbjct: 241 GVTGRKIIVDTYGGMSRHGGGAFSGKDPSKVDRSAAYAARYVAKNIVASGLAARCEIQLS 300 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIG+ EP+S+ +D++ TGKI + ++ LV+ FD RP + L+L + ++KTA Y Sbjct: 301 YAIGIAEPISIMIDTFNTGKISNSALISLVRSIFDLRPYGLIKMLNLLQ--PIYLKTAVY 358 Query: 1022 GHFGRDDADFTWE 1060 GHFGR +F WE Sbjct: 359 GHFGR--KEFPWE 369
>Q87AY6:METK_XYLFT S-adenosylmethionine synthetase - Xylella fastidiosa (strain| Temecula1 / ATCC 700964) Length = 403 Score = 303 bits (777), Expect = 9e-82 Identities = 182/410 (44%), Positives = 235/410 (57%), Gaps = 71/410 (17%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET+ KT + ++ GEITT A Sbjct: 3 SYLFTSESVSEGHPDKVADQISDAVLDAILVQDPRARVACETMVKTGVAIIAGEITTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 VD E + R +IG+ S DVG D C VL I +QSPDI QGV K+ EE GAGD Sbjct: 63 VDLEALTRKVIVDIGYNSSDVGFDGATCGVLNLIGKQSPDINQGVD---RKKAEEQGAGD 119 Query: 461 QGIMFGYATDETPELMP----LSH------------------------------------ 520 QG+MFGYAT+ET MP +SH Sbjct: 120 QGLMFGYATNETDSYMPAAIHISHRLVEQQAKIRKKSNSLLPWLRPDAKAQITLRYEDGV 179 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L ++E ++KPV+P+K+L + T FH+NP+G+FVIGGP Sbjct: 180 ASAIDAVVLSTQHDPGIKQKDLVEAVREEILKPVLPSKWLHKGTKFHINPTGKFVIGGPV 239 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS +Y R AK+++A+GLA RC V Sbjct: 240 GDCGLTGRKIIVDTYGGSARHGGGAFSGKDPSKVDRSASYAVRYVAKNVVAAGLADRCEV 299 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP+S+ V ++GTGKIPD +I KL+ ++FD RP I LDL + + Sbjct: 300 QVSYAIGVAEPISISVTTFGTGKIPDDKIEKLICQHFDLRPYGIIKMLDLIH--PIYQPS 357 Query: 1013 AAYGHFGRDDAD---------------FTWEVVKPLKFDKASA*EQDITL 1117 A+YGHFGR + F+WE K DKA D L Sbjct: 358 ASYGHFGRKPRELAYTNSNGERVVATAFSWE-----KIDKAEVLRADAKL 402
>Q5ZTY6:METK_LEGPH S-adenosylmethionine synthetase - Legionella pneumophila subsp.| pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) Length = 382 Score = 303 bits (777), Expect = 9e-82 Identities = 173/375 (46%), Positives = 225/375 (60%), Gaps = 54/375 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E ++FTSESV+EGHPDK+ DQ+SDA+LDA LAQD ++VACE + KT MV+V GEITTKA Sbjct: 3 EVYVFTSESVSEGHPDKIADQISDAILDAILAQDPKARVACEVLVKTGMVLVGGEITTKA 62 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 VD E+I R ++IG+ S +G D + C VL I +QSPDIAQGV TK +GAG Sbjct: 63 WVDVEEITRHVIKDIGYNSSQMGFDWESCAVLSAIGKQSPDIAQGVDNQQTKI---LGAG 119 Query: 458 DQGIMFGYATDETPELMPL----SHVLATKLGAR-------------------------- 547 DQG+MFGYA+ ET MP +H L KL Sbjct: 120 DQGLMFGYASRETDVFMPAPIAYAHRLMEKLAKARKSGQLPWLRPDAKCQLTLKYEQGMP 179 Query: 548 ------------------------LKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 ++E +IK V+PA++L++ T + +NP+GRFVIGGP G Sbjct: 180 VEVDTVVFSTQHSPDIEHKDLVEAIREEIIKSVLPAEWLNDKTRYFINPTGRFVIGGPLG 239 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA +C +Q Sbjct: 240 DCGLTGRKIIVDTYGGMARHGGGCFSGKDPSKVDRSAAYAARHVAKNIVAAGLADKCELQ 299 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 ISYAIGV EP S+FVD++GTG++ + EI+ L+ +FD P I DL + R +TA Sbjct: 300 ISYAIGVAEPTSIFVDTFGTGRLKNSEIIDLIHTHFDLTPQGIIDQHDLLRPIYR--QTA 357 Query: 1016 AYGHFGRDDADFTWE 1060 YGH+GR+ F WE Sbjct: 358 TYGHYGRE--SFPWE 370
>Q49YL6:METK_STAS1 S-adenosylmethionine synthetase - Staphylococcus saprophyticus subsp.| saprophyticus (strain ATCC 15305 / DSM 20229) Length = 398 Score = 303 bits (775), Expect = 2e-81 Identities = 176/391 (45%), Positives = 224/391 (57%), Gaps = 62/391 (15%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LD L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDEILKDDPNARVACETTVTTGMALISGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE------- 445 K+VR+T + IG+ G D+ VL I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKEIGYTRAKFGYDSQTMAVLTAIDEQSPDIAQGVDTALEYRDEASEAEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMP----LSH------------------------------- 520 GAGDQG+MFGYAT+ET MP LSH Sbjct: 127 TGAGDQGLMFGYATNETDTYMPLPIFLSHQLAKRLSDVRKDEILKYLRPDGKVQVTVEYD 186 Query: 521 -----------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 VL+T+ + +K HVI P +P LDE T F++NP+GRFVI Sbjct: 187 EQDKPVRIDTIVLSTQHAEDIELDQIKDDIKTHVIYPTVPESLLDEQTKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+ LA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAQLAE 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++GTGK+ + E+++ V+++FD RP I LDLK Sbjct: 307 KCEVQLAYAIGVAEPVSISIDTFGTGKVSEYELVEAVRKHFDLRPAGIIKMLDLKH--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKAS 1093 + +TAAYGHFGR D WE K DK + Sbjct: 365 YKQTAAYGHFGRTDVLLPWE-----KLDKVN 390
>Q65UT4:METK_MANSM S-adenosylmethionine synthetase - Mannheimia succiniciproducens| (strain MBEL55E) Length = 383 Score = 303 bits (775), Expect = 2e-81 Identities = 177/374 (47%), Positives = 222/374 (59%), Gaps = 54/374 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLD L QD ++VACET KT M +V GEITT A Sbjct: 3 SYLFTSESVSEGHPDKIADQISDAVLDEILKQDPKARVACETYVKTGMALVGGEITTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 VD E I R +IG+ S ++G D C VL I +QS DI QGV P GAGD Sbjct: 63 VDIEYIARQVICDIGYTSSEMGFDGHSCAVLNGIGKQSSDINQGVD---RDDPLNQGAGD 119 Query: 461 QGIMFGYATDETPELMPLSH---------------------------------------- 520 QGIMFGYAT+ET LMP + Sbjct: 120 QGIMFGYATNETEVLMPAAITYAHRLMERQAWVRKNGTLPWLRPDAKSQVTLKYENNKIV 179 Query: 521 -----VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGD 658 VL+T+ L + E +IKPV+PAK+L ++T + +NP+GRFVIGGP GD Sbjct: 180 GVDAVVLSTQHSDSVTQEDLHEAVMEEIIKPVLPAKWLSKDTKYFINPTGRFVIGGPMGD 239 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+ Sbjct: 240 CGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQL 299 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAA 1018 SYAIGV EP S+ V+++GTGK+ D ++ LV+E+FD RP + LDL K R +TAA Sbjct: 300 SYAIGVAEPTSIMVETFGTGKVADELLVALVREHFDLRPYGLIKMLDLIKPIYR--ETAA 357 Query: 1019 YGHFGRDDADFTWE 1060 YGHFGR+ F WE Sbjct: 358 YGHFGRE--QFPWE 369
>Q5WV18:METK_LEGPL S-adenosylmethionine synthetase - Legionella pneumophila (strain| Lens) Length = 382 Score = 303 bits (775), Expect = 2e-81 Identities = 173/375 (46%), Positives = 224/375 (59%), Gaps = 54/375 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E ++FTSESV+EGHPDK+ DQ+SDA+LDA LAQD ++VACE + KT MV+V GEITTKA Sbjct: 3 EVYVFTSESVSEGHPDKIADQISDAILDAILAQDPKARVACEVLVKTGMVLVGGEITTKA 62 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 VD E I R ++IG+ S +G D + C VL I +QSPDIAQGV TK +GAG Sbjct: 63 WVDVEDITRHVIKDIGYNSSQMGFDWESCAVLSAIGKQSPDIAQGVDNQQTKI---LGAG 119 Query: 458 DQGIMFGYATDETPELMPL----SHVLATKLGAR-------------------------- 547 DQG+MFGYA+ ET MP +H L KL Sbjct: 120 DQGLMFGYASRETDVFMPAPIAYAHRLMEKLAKARKSGQLPWLRPDAKCQLTLKYEQGMP 179 Query: 548 ------------------------LKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 ++E +IK V+PA++L++ T + +NP+GRFVIGGP G Sbjct: 180 VEVDTVVFSTQHSPDIEHKDLVEAIREEIIKSVLPAEWLNDKTRYFINPTGRFVIGGPLG 239 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA +C +Q Sbjct: 240 DCGLTGRKIIVDTYGGMARHGGGCFSGKDPSKVDRSAAYAARHVAKNIVAAGLADKCELQ 299 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 ISYAIGV EP S+FVD++GTG++ + EI+ L+ +FD P I DL + R +TA Sbjct: 300 ISYAIGVAEPTSIFVDTFGTGRLKNSEIIDLIHTHFDLTPQGIIDQHDLLRPIYR--QTA 357 Query: 1016 AYGHFGRDDADFTWE 1060 YGH+GR+ F WE Sbjct: 358 TYGHYGRE--SFPWE 370
>Q7VNG7:METK_HAEDU S-adenosylmethionine synthetase - Haemophilus ducreyi| Length = 386 Score = 303 bits (775), Expect = 2e-81 Identities = 178/384 (46%), Positives = 227/384 (59%), Gaps = 54/384 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV+EGHPDK+ DQ+SDAVLD L QD ++VACET KT M +V GEITT A VD Sbjct: 10 LFTSESVSEGHPDKIADQISDAVLDEILKQDPKARVACETYVKTGMALVGGEITTSAWVD 69 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E + R +IG+ D+G DA C VL I +QSPDI QGV + P GAGDQG Sbjct: 70 IENLTRQVIYDIGYSHSDMGFDAHSCAVLNAIGKQSPDINQGVD---REDPLAQGAGDQG 126 Query: 467 IMFGYATDETPELMPL-------------------------------------------- 514 IMFGYAT+ET LMP Sbjct: 127 IMFGYATNETDVLMPAPITYAHRLMQRQAEVRKSGKLAWLRPDAKSQLTFAYENNQIIGI 186 Query: 515 -SHVLATKLGARLK---------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 + VL+T+ +K E +IKP +P+K+L+++T + +NP+GRFVIGGP GD G Sbjct: 187 DAVVLSTQHAEEVKQKELIEGVMEEIIKPTLPSKWLNQHTKYFINPTGRFVIGGPMGDCG 246 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY AR AKSI+A+GLA RC +Q+SY Sbjct: 247 LTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKSIVAAGLADRCEIQLSY 306 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV +P S+ V+++GTGK+ + ++KL+ +NFD RP + LDL + R +TAAYG Sbjct: 307 AIGVADPTSIMVETFGTGKVSNDTLVKLIYQNFDLRPYGLIKMLDLIQPIYR--ETAAYG 364 Query: 1025 HFGRDDADFTWEVVKPLKFDKASA 1096 HFGR+ F WE + DKA A Sbjct: 365 HFGRE--QFPWE-----RTDKAEA 381
>Q9PGB0:METK_XYLFA S-adenosylmethionine synthetase - Xylella fastidiosa| Length = 403 Score = 302 bits (774), Expect = 2e-81 Identities = 181/410 (44%), Positives = 235/410 (57%), Gaps = 71/410 (17%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLDA L QD ++VACET+ KT + ++ GEITT A Sbjct: 3 SYLFTSESVSEGHPDKVADQISDAVLDAILVQDPRARVACETMVKTGVAIIAGEITTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 VD E + R +IG+ S DVG D C VL I +QSPDI QGV K+ EE GAGD Sbjct: 63 VDLEALTRKVIVDIGYNSSDVGFDGATCGVLNLIGKQSPDINQGVD---RKKAEEQGAGD 119 Query: 461 QGIMFGYATDETPELMP----LSH------------------------------------ 520 QG+MFGYAT+ET MP +SH Sbjct: 120 QGLMFGYATNETDSYMPAAIHISHRLVEQQAKIRKKSNSPLPWLRPDAKAQITLRYEDGV 179 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L ++E ++KPV+P+K+L + T FH+NP+G+FVIGGP Sbjct: 180 ASAIDAVVLSTQHDPGIKQKDLVEAVREEILKPVLPSKWLHKGTKFHINPTGKFVIGGPV 239 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS +Y R AK+++A+GLA RC V Sbjct: 240 GDCGLTGRKIIVDTYGGSARHGGGAFSGKDPSKVDRSASYAVRYVAKNVVAAGLADRCEV 299 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP+S+ V ++GTGKI D +I KL++++FD RP I LDL + + Sbjct: 300 QVSYAIGVAEPISISVTTFGTGKISDDKIEKLIRQHFDLRPYGIIKMLDLIH--PIYQPS 357 Query: 1013 AAYGHFGRDDAD---------------FTWEVVKPLKFDKASA*EQDITL 1117 A+YGHFGR + F+WE K DKA D L Sbjct: 358 ASYGHFGRKPRELAYTNSNGERVVATAFSWE-----KIDKAEVLRADAKL 402
>Q4L7C7:METK_STAHJ S-adenosylmethionine synthetase - Staphylococcus haemolyticus (strain| JCSC1435) Length = 398 Score = 302 bits (774), Expect = 2e-81 Identities = 175/391 (44%), Positives = 220/391 (56%), Gaps = 62/391 (15%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LD L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDEILKDDPNARVACETTVTTGMALISGEISTSTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T + IG+ G D VL I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKGIGYTRAKYGYDYQTMAVLTAIDEQSPDIAQGVDKALEYRNDISEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMPL----SHVLATKLG------------------------ 541 GAGDQG+MFGYAT+ET MPL SH LA +L Sbjct: 127 TGAGDQGLMFGYATNETETYMPLPIFLSHQLAKRLSDVRKDGILNYLRPDGKVQVTVEYD 186 Query: 542 ---------------------------ARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 + +KEHVI P +P +D T F +NP+GRFVI Sbjct: 187 ESDKPKRIDTIVVSSQHADDIELEQIQSDIKEHVIYPTVPEGLIDNETKFFINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAD 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ +D++ TGK+ + ++++ V+ NFD RP I LDLK Sbjct: 307 QCEVQLAYAIGVAEPVSISIDTFKTGKVSEAQLVEAVRANFDLRPAGIIKMLDLKH--PI 364 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKAS 1093 + +TAAYGHFGR D WE K DK + Sbjct: 365 YKQTAAYGHFGRTDVLLPWE-----KLDKVN 390
>Q6FAQ6:METK_ACIAD S-adenosylmethionine synthetase - Acinetobacter sp. (strain ADP1)| Length = 388 Score = 302 bits (774), Expect = 2e-81 Identities = 174/389 (44%), Positives = 230/389 (59%), Gaps = 56/389 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E +FTSESV+EGHPDK+ DQ+SDA+LDA L +D ++VACET+ KT V++ GEITT A Sbjct: 3 EYAVFTSESVSEGHPDKMADQISDAILDAILKEDPYARVACETLVKTGAVVLAGEITTTA 62 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 VD+E IVR T IG+ D+G D C ++ I +QSP+IAQGV ++PE+ GAG Sbjct: 63 NVDFEAIVRQTVNGIGYHHSDLGFDGSTCAIINMIGKQSPEIAQGVD---RQKPEDQGAG 119 Query: 458 DQGIMFGYATDETPELMPLSHVLATKL--------------------------------- 538 DQG+MFGYA+ ET LMP A +L Sbjct: 120 DQGLMFGYASRETDVLMPAPISYAHRLMERQAELRRSGALPWLRPDAKSQVTFAYENGMP 179 Query: 539 -----------------GARLKEHVI----KPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 A+LKE VI KPVIP++ T FH+NP+G FVIGGP G Sbjct: 180 VRLDAVVLSTQHDPEISQAQLKEAVIEEIVKPVIPSEMFHAGTKFHINPTGMFVIGGPVG 239 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA +C +Q Sbjct: 240 DCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLADKCEIQ 299 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 +SYAIGV EP S+ ++++ T K+ + I+ LV+E+FD RP I+ LDL + + +TA Sbjct: 300 VSYAIGVAEPTSISINTFNTAKVDEELIIALVREHFDLRPYGITRMLDLLQ--PMYKQTA 357 Query: 1016 AYGHFGRDDAD--FTWEVVKPLKFDKASA 1096 AYGHFGR+ +D FTWE ++ K +A Sbjct: 358 AYGHFGREGSDTAFTWEKTDKVEVLKDAA 386
>Q60CG7:METK_METCA S-adenosylmethionine synthetase - Methylococcus capsulatus| Length = 389 Score = 302 bits (773), Expect = 3e-81 Identities = 169/376 (44%), Positives = 224/376 (59%), Gaps = 54/376 (14%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 + +F+FTSESV+EGHPDK+ DQVSDAVLDA LAQD ++VA ET+ KT MV++ GE+TT Sbjct: 2 SNSFIFTSESVSEGHPDKIADQVSDAVLDAILAQDPKARVAVETLVKTGMVVLAGEVTTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VD E++VR IG+ + ++G D C VL I +QSPDIA GV E GA Sbjct: 62 AWVDTEELVRKVVHEIGYDNPEIGFDWQSCAVLTAIGKQSPDIAMGVDEF---DDHEQGA 118 Query: 455 GDQGIMFGYATDETPELMPLSHVLATKL---GARLKEHVIKP------------------ 571 GDQG+MFGYAT+ET LMP A +L A +++H + P Sbjct: 119 GDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKHKVLPWLRPDAKSQVTFRYEEGK 178 Query: 572 ---------------------------------VIPAKYLDENTIFHLNPSGRFVIGGPH 652 V+P ++L ++T + +NP+G FVIGGP Sbjct: 179 PVAVDAVVLSTQHAPDVAQKDIREAVMEEIIYHVLPREWLHKDTKYFINPTGSFVIGGPV 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY+ R AK+I+A+GLA RC + Sbjct: 239 GDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYMGRYVAKNIVAAGLAERCEI 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ ++++GTG+I + ++KLV+E+FD RP + LDL + R T Sbjct: 299 QVSYAIGVAEPTSISIETFGTGRIAEETLVKLVREHFDLRPKGLITMLDLLRPIYR--PT 356 Query: 1013 AAYGHFGRDDADFTWE 1060 AAYGHFGR + FTWE Sbjct: 357 AAYGHFGRTEGTFTWE 372
>Q3J7R5:METK_NITOC S-adenosylmethionine synthetase - Nitrosococcus oceani (strain ATCC| 19707 / NCIMB 11848) Length = 403 Score = 301 bits (772), Expect = 3e-81 Identities = 178/395 (45%), Positives = 234/395 (59%), Gaps = 58/395 (14%) Frame = +2 Query: 110 FTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVDY 289 FTSESV+EGHPDK+ DQ+SD +LDA LAQD ++VACET+ KT MV+V GEITT+A +DY Sbjct: 7 FTSESVSEGHPDKVADQISDVILDAILAQDRRARVACETLVKTGMVLVAGEITTQAHIDY 66 Query: 290 EKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQGI 469 E+I+R+T IG+ ++G D C V+ I +QS DIAQGV E+ GAGDQG+ Sbjct: 67 EQIIRETITEIGYNHSEIGFDGATCAVVNAIGKQSSDIAQGVDRELE---EDQGAGDQGM 123 Query: 470 MFGYATDETPELM--PLSH----------------------------------------- 520 MFGYA+DET LM P+++ Sbjct: 124 MFGYASDETDVLMPAPITYAHRLVQRQAEIRRNGELPWLRPDAKSQVTLLYEDDVPVAID 183 Query: 521 --VLATKLGARLK---------EHVIKPVIPAKYL----DENTIFHLNPSGRFVIGGPHG 655 VL+T+ + E +IKPV+PA + EN H+NP+G F+IGGP G Sbjct: 184 AIVLSTQHSPEISQATLREAVIETIIKPVLPADWFAHCRSEN--IHVNPTGNFIIGGPMG 241 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII+DTY KDP+KVDRS AY R AK+++A+GLA RC VQ Sbjct: 242 DCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNLVAAGLAERCEVQ 301 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 ISYAIGV EP SV V+++GTG+I + +++L++ +FD RP + LDL + R KTA Sbjct: 302 ISYAIGVAEPTSVSVNTFGTGRIAESRLVELIQAHFDLRPVGLLQMLDLIRPIYR--KTA 359 Query: 1016 AYGHFGRDDADFTWEVVKPLKFDKASA*EQDITLG 1120 AYGHFGR++ +FTWE + DKA A LG Sbjct: 360 AYGHFGREEPEFTWE-----QTDKAEALRDAAGLG 389
>Q5LZI0:METK_STRT1 S-adenosylmethionine synthetase - Streptococcus thermophilus (strain| CNRZ 1066) Length = 397 Score = 301 bits (771), Expect = 5e-81 Identities = 179/396 (45%), Positives = 227/396 (57%), Gaps = 62/396 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D D+ VA ET T V + GE++T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILAEDPDAHVAAETAVYTGSVHIFGEVSTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP----- 439 A VD ++VRDT IG+ + + G A+ V ++ +QSPDIAQGV+ R Sbjct: 62 AYVDINRVVRDTIAEIGYNNAEYGFAAESVGVHPSLIEQSPDIAQGVNESLEVRGTGDQD 121 Query: 440 --EEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK---------------- 553 + +GAGDQG+MFG+A DETPE MPL SH L KL K Sbjct: 122 SLDLIGAGDQGLMFGFAIDETPEFMPLPVSLSHKLVKKLADLRKSGEISYLRPDAKSQVT 181 Query: 554 -----------------------------------EHVIKPVIPAKYLDENTIFHLNPSG 628 E VIK VIPA+YLDE+T F +NP+G Sbjct: 182 VEYDENDQPVRVDTVVISTQHDPEATNDQIRHDVIEKVIKAVIPAEYLDEDTKFFINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I+A+ Sbjct: 242 RFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLAR+ VQ++YAIGV P+SV VD++GT + +R++ V++ FD RP I LDLK+ Sbjct: 302 GLARKAEVQLAYAIGVANPVSVRVDTFGTATVAERKLESAVRDLFDLRPAGIIQMLDLKR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 R +TAAYGH GR D D WE K DK A Sbjct: 362 PIYR--QTAAYGHMGRTDVDLPWE-----KLDKVDA 390
>Q5M434:METK_STRT2 S-adenosylmethionine synthetase - Streptococcus thermophilus (strain| ATCC BAA-250 / LMG 18311) Length = 397 Score = 300 bits (769), Expect = 8e-81 Identities = 179/396 (45%), Positives = 227/396 (57%), Gaps = 62/396 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D D+ VA ET T V V GE++T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILAEDPDAHVAAETAVYTGSVHVFGEVSTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP----- 439 A VD ++VRDT IG+ + + G A+ V ++ +QSPDIAQGV+ R Sbjct: 62 AYVDINRVVRDTIAEIGYNNAEYGFAAESVGVHPSLIEQSPDIAQGVNESLEVRGTGDQD 121 Query: 440 --EEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK---------------- 553 + +GAGDQG+MFG+A DETPE MPL SH L KL K Sbjct: 122 SLDLIGAGDQGLMFGFAIDETPEFMPLPVSLSHKLVKKLADLRKSGEISYLRPDAKSQVT 181 Query: 554 -----------------------------------EHVIKPVIPAKYLDENTIFHLNPSG 628 E VIK VIPA+YLDE+T F +NP+G Sbjct: 182 VEYDENDQPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPAEYLDEDTKFFINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I+A+ Sbjct: 242 RFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLA++ VQ++YAIGV P+SV VD++GT + +R++ V++ FD RP I LDLK+ Sbjct: 302 GLAKKAEVQLAYAIGVANPVSVRVDTFGTATVAERKLESAVRDLFDLRPAGIIQMLDLKR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 R +TAAYGH GR D D WE K DK A Sbjct: 362 PIYR--QTAAYGHMGRTDVDLPWE-----KLDKVDA 390
>Q8CNT5:METK_STAES S-adenosylmethionine synthetase - Staphylococcus epidermidis (strain| ATCC 12228) Length = 399 Score = 300 bits (769), Expect = 8e-81 Identities = 173/391 (44%), Positives = 223/391 (57%), Gaps = 62/391 (15%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LD L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDEILKDDPNARVACETTVTTGMALISGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T ++IG+ G D+ VL I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKDIGYTRAKYGYDSQTMAVLTAIDEQSPDIAQGVDKALEYRNDISEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMPL----SHVLA---------------------------- 529 GAGDQG+MFGYATDET MPL SH LA Sbjct: 127 TGAGDQGLMFGYATDETDTYMPLPIFLSHQLAKRLADVRKDEILDYLRPDGKVQVTVEYG 186 Query: 530 -----------------------TKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 ++ +K HVI P + LD+ T F++NP+GRFVI Sbjct: 187 EDDKPRRIDTIVVSTQHAEDVELAQIEKDIKTHVIYPTVDKALLDDETKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA+ Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAK 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ ++++ TGK+ + +++ V+++FD RP I LDLK+ R Sbjct: 307 QCEVQLAYAIGVAEPVSISINTFDTGKVSEARLVEAVRKHFDLRPAGIIKMLDLKQPIYR 366 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKAS 1093 +TAAYGHFGR D WE K DK + Sbjct: 367 --QTAAYGHFGRTDVLLPWE-----KLDKVN 390
>Q5HNB8:METK_STAEQ S-adenosylmethionine synthetase - Staphylococcus epidermidis (strain| ATCC 35984 / RP62A) Length = 399 Score = 300 bits (769), Expect = 8e-81 Identities = 173/391 (44%), Positives = 223/391 (57%), Gaps = 62/391 (15%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQVSDA+LD L D +++VACET T M ++ GEI+T VD Sbjct: 7 LFTSESVTEGHPDKIADQVSDAILDEILKDDPNARVACETTVTTGMALISGEISTTTYVD 66 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 K+VR+T ++IG+ G D+ VL I++QSPDIAQGV R E Sbjct: 67 IPKVVRETIKDIGYTRAKYGYDSQTMAVLTAIDEQSPDIAQGVDKALEYRNDISEEEIEA 126 Query: 446 VGAGDQGIMFGYATDETPELMPL----SHVLA---------------------------- 529 GAGDQG+MFGYATDET MPL SH LA Sbjct: 127 TGAGDQGLMFGYATDETDTYMPLPIFLSHQLAKRLADVRKDEILDYLRPDGKVQVTVEYG 186 Query: 530 -----------------------TKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 ++ +K HVI P + LD+ T F++NP+GRFVI Sbjct: 187 EDDKPRRIDTIVVSTQHAEDVELAQIEKDIKTHVIYPTVDKALLDDETKFYINPTGRFVI 246 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+GLA+ Sbjct: 247 GGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAK 306 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C VQ++YAIGV EP+S+ ++++ TGK+ + +++ V+++FD RP I LDLK+ R Sbjct: 307 QCEVQLAYAIGVAEPVSISINTFDTGKVSEARLVEAVRKHFDLRPAGIIKMLDLKQPIYR 366 Query: 1001 FIKTAAYGHFGRDDADFTWEVVKPLKFDKAS 1093 +TAAYGHFGR D WE K DK + Sbjct: 367 --QTAAYGHFGRTDVLLPWE-----KLDKVN 390
>P56878:METK_RICPR S-adenosylmethionine synthetase - Rickettsia prowazekii| Length = 380 Score = 300 bits (768), Expect = 1e-80 Identities = 164/375 (43%), Positives = 222/375 (59%), Gaps = 54/375 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 + F+FTSESV+EGHPDK+ DQ+SDAVLD L D + +VACET T +V+V GEITT Sbjct: 2 KNFVFTSESVSEGHPDKIADQISDAVLDEILKHDPNGRVACETFVTTGLVLVGGEITTNT 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 VD E++VR+ + IG+ + + G D C V+ +I +QSPDIA G+ + EE+GAG Sbjct: 62 YVDIEQVVRNKIQEIGYNNPNYGFDGSCCAVISSIIKQSPDIAMGIDN---ENEEEIGAG 118 Query: 458 DQGIMFGYATDETPELMPL----------------------------------------- 514 DQG++FGYA +ET LMP Sbjct: 119 DQGMVFGYACNETKSLMPAPIYYAHLLMKRQAYLRKQNILSWLRPDAKSQVTLRYENNKP 178 Query: 515 ----SHVLATKLGARLK---------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 S VL+T+ ++ E +IKP +P L ++T + +NP+GRFVIGGP Sbjct: 179 IVIDSVVLSTQHHPEIQQKDLIEAVIEEIIKPTLPTNLLHKDTKYLINPTGRFVIGGPVA 238 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII+D+Y KDPTK+DRS AY+AR AK+I+ +GLA RC +Q Sbjct: 239 DCGLTGRKIIVDSYGGMAKHGGGCFSGKDPTKIDRSAAYMARYIAKNIVGAGLADRCEIQ 298 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 ISYAIGV +P+SV+ +++GT K+ + + KL+ E+FD RPG I NL L + KTA Sbjct: 299 ISYAIGVADPVSVYAETFGTSKLSNEQTTKLITEHFDMRPGKIIKNLKLHT--QCYQKTA 356 Query: 1016 AYGHFGRDDADFTWE 1060 YGHFGR+D +FTWE Sbjct: 357 TYGHFGREDENFTWE 371
>Q21RM4:METK_RHOFD S-adenosylmethionine synthetase - Rhodoferax ferrireducens (strain| DSM 15236 / ATCC BAA-621 / T118) Length = 393 Score = 300 bits (768), Expect = 1e-80 Identities = 177/393 (45%), Positives = 228/393 (58%), Gaps = 59/393 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A FLFTSESV+EGHPDK+ DQ+SDA+LDA QD S+VA ET+ T +V++ GEITT Sbjct: 2 ANDFLFTSESVSEGHPDKVADQISDAILDAIFKQDPKSRVAAETLCNTGLVVLAGEITTN 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VDY ++ RDT + IG+ + + G+D C VLV ++QS DIAQGV H + GA Sbjct: 62 AHVDYIQVARDTLKRIGYDNTEYGIDYKGCAVLVAYDKQSNDIAQGV-DHASDDHLNTGA 120 Query: 455 GDQGIMFGYATDETPELMPLSHVLATKLGARL---------------------------K 553 GDQG+MFGYA +ETPELMP A +L R K Sbjct: 121 GDQGLMFGYACNETPELMPAPIYYAHRLVERQAQLRKDGRLPFLRPDAKSQITMHYVDGK 180 Query: 554 EHVIKPVI--------------------------------PAKYLDENTIFHLNPSGRFV 637 H I V+ P ++L +T + +NP+GRFV Sbjct: 181 PHSIDTVVLSSQHSPEMSNGLTMKPAFIEAVMEDIIKPVCPKEWLTADTKYLINPTGRFV 240 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 +GGP GD GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA Sbjct: 241 VGGPQGDCGLTGRKIIVDTYGGACPHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLA 300 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 R+C +Q++YAIGV +P++V V + GTG IPD +I +LV E FD RP I LDL + Sbjct: 301 RQCQIQVAYAIGVAKPMNVTVYTEGTGVIPDDKIAELVHELFDLRPKGIIQMLDLLR--P 358 Query: 998 RFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 + KTAAYGHFGR++ +FTWE + DKA A Sbjct: 359 IYEKTAAYGHFGREEPEFTWE-----RTDKAQA 386
>Q8Y347:METK_RALSO S-adenosylmethionine synthetase - Ralstonia solanacearum (Pseudomonas| solanacearum) Length = 396 Score = 300 bits (768), Expect = 1e-80 Identities = 175/373 (46%), Positives = 226/373 (60%), Gaps = 54/373 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 FLFTSESV+EGHPDK+ DQ+SDA+LDA LAQD ++VA ET+ T +V++ GEITT A V Sbjct: 5 FLFTSESVSEGHPDKVADQISDAILDAILAQDKYARVAAETLCNTGLVVLAGEITTSANV 64 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 DY + R+T + IG+ + D G+D C VLV ++QSPDIAQGV + GAGDQ Sbjct: 65 DYIHVARETIKRIGYDNTDYGIDYKGCAVLVAYDKQSPDIAQGVDRASDDYLNQ-GAGDQ 123 Query: 464 GIMFGYATDET---------------------------PELMPLSH-------------- 520 G+MFGYA DET P L P + Sbjct: 124 GLMFGYACDETPELMPFPIYYAHRLVERQSQLRRDGRLPWLRPDAKSQVTVRYVNGKPHS 183 Query: 521 ----VLATKLGARLK---------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDA 661 VL+T+ + E +IKPV+P+ L E T + +NP+GRFVIGGP GD Sbjct: 184 VDTVVLSTQHAPEISQEQIREAVIEEIIKPVLPSHMLAE-TKYLVNPTGRFVIGGPQGDC 242 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 GLTGRKII+DTY KDP+KVDRS AY AR AK+++A+GLAR+C VQ+S Sbjct: 243 GLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLARQCQVQVS 302 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIGV P+++ V + GTG IPD +I KLV+E+FD RP I LDL + + KTAAY Sbjct: 303 YAIGVARPINITVYTEGTGVIPDEQIAKLVQEHFDLRPKGIVQMLDLLR--PIYGKTAAY 360 Query: 1022 GHFGRDDADFTWE 1060 GHFGR++ +F+WE Sbjct: 361 GHFGREEPEFSWE 373
>Q73JR4:METK_TREDE S-adenosylmethionine synthetase - Treponema denticola| Length = 389 Score = 300 bits (767), Expect = 1e-80 Identities = 179/385 (46%), Positives = 224/385 (58%), Gaps = 56/385 (14%) Frame = +2 Query: 110 FTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVDY 289 FTSESV+EGHPDKLCDQ+SDAVLDACL D +S VACET T +V+V GEITT VD Sbjct: 8 FTSESVSEGHPDKLCDQISDAVLDACLRDDPESHVACETFASTALVLVGGEITTNTYVDI 67 Query: 290 EKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGH-FTKRPEEVGAGDQG 466 ++I R IG+ + D GLD V+ I QSPDI+QGV G + + GAGDQG Sbjct: 68 QEIARSIAEEIGYTNTDFGLDCHSMAVMNMIHSQSPDISQGVDGTGLDEYKGQQGAGDQG 127 Query: 467 IMFGYATDETPELMP--------------------------------------------- 511 +MFG+A ETPELMP Sbjct: 128 MMFGFACKETPELMPAPIMFSHSVLRYAAKLRKEKVIPWLRPDSKTQITVKYEGFKPIKI 187 Query: 512 ----LSH-----VLATKLGARLKEHVIKPVI-PAKYLDENTIFHLNPSGRFVIGGPHGDA 661 LSH V +L L VIKPV+ P L ++T + +NP+GRFVIGGP GD Sbjct: 188 DTVVLSHQHYPDVQYDELKDTLINRVIKPVLGPTGLLADDTKYFINPTGRFVIGGPFGDT 247 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 GLTGRKII+DTY KDP+KVDRS AY+AR AK+++A+ LARRC VQ++ Sbjct: 248 GLTGRKIIVDTYGGMGRHGGGAFSGKDPSKVDRSAAYMARYIAKNVVAADLARRCEVQLA 307 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIGVP P++V VD++GTG++P+ +I K +KE FD P I LDLK+ + +TAAY Sbjct: 308 YAIGVPFPVAVRVDTFGTGEVPEEKIEKAIKEVFDMSPAGIIKTLDLKR--PIYKETAAY 365 Query: 1022 GHFGRDDADFTWEVVKPLKFDKASA 1096 GHFGR +F+WE K DK A Sbjct: 366 GHFGR--PEFSWE-----KTDKTEA 383
>Q7NZF9:METK_CHRVO S-adenosylmethionine synthetase - Chromobacterium violaceum| Length = 389 Score = 300 bits (767), Expect = 1e-80 Identities = 172/387 (44%), Positives = 232/387 (59%), Gaps = 56/387 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQ+SDA+LDA L +D ++VA ET+ T +V++ GEITT A V Sbjct: 4 YLFTSESVSEGHPDKVADQISDAILDAILREDKHARVAAETLVNTGLVVLAGEITTTANV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 DY KI R+T + IG+ ++G D C V+ ++QSPDIAQGV+ + GAGDQ Sbjct: 64 DYIKIARETIKRIGYDDSELGFDFRGCAVMACYDKQSPDIAQGVNEGEGLDLNQ-GAGDQ 122 Query: 464 GIMFGYATDET---------------------------PELMPLSH-------------- 520 G+MFGYA DET P L P + Sbjct: 123 GLMFGYACDETPTLMPFPIYYAHRLVQRQAELRKDGRLPWLRPDAKSQITCVYDAATGLP 182 Query: 521 ------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 VL+T+ L + E ++KPV+P + + T F +NP+GRFVIGGP G Sbjct: 183 KRIDTVVLSTQHSPDIDHKTLSEAVIEDIVKPVLPPEMITPETKFLINPTGRFVIGGPMG 242 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLAR+C +Q Sbjct: 243 DCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLARQCQIQ 302 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 +SYAIGV EP S+ VD++GT KIP+ +I++LVK++FD RP I LDL + + KTA Sbjct: 303 VSYAIGVAEPTSIAVDTFGTNKIPNEKIVELVKKHFDLRPKGIIQMLDLLR--PIYGKTA 360 Query: 1016 AYGHFGRDDADFTWEVVKPLKFDKASA 1096 AYGHFGR++ +F+WE ++ +A A Sbjct: 361 AYGHFGREEPEFSWERTDKVEALRADA 387
>Q84FD3:METK_MYXXA S-adenosylmethionine synthetase - Myxococcus xanthus| Length = 396 Score = 299 bits (766), Expect = 2e-80 Identities = 168/378 (44%), Positives = 220/378 (58%), Gaps = 53/378 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 FLFTSESV EGHPDK+ DQ+SD VLDA +A+D ++VA ET+ KT + +V GE+TT V Sbjct: 5 FLFTSESVTEGHPDKIADQISDGVLDAIIAKDPQARVAVETLVKTGLAIVAGEVTTNCYV 64 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 D K+VR T IG+ +G D + C V+V IE QS DIA+GV ++ GAGDQ Sbjct: 65 DIPKLVRSTICRIGYTDSSMGYDGNTCGVMVAIEGQSQDIARGVDNK-----KDQGAGDQ 119 Query: 464 GIMFGYATDETPELMPL----SHVLATKLG-ARLKEH----------------------- 559 G+MFG+A DETPELMP +H + +L R K+H Sbjct: 120 GMMFGFACDETPELMPAPIHYAHAITRRLADVRRKQHPWIRPDGKSQVTVEYRDGRPARI 179 Query: 560 -------------------------VIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 VI +P K +D T F +NP+GR V GGP GD+G Sbjct: 180 DAVVVSTQHSDEVSNKKIQEAIREDVIANALPKKLIDNKTKFFINPTGRLVAGGPMGDSG 239 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRS AY+ R AK+++A+GLARRC VQ+SY Sbjct: 240 LTGRKIIVDTYGGMGRHGGGAFSGKDPSKVDRSAAYMGRHIAKTVVAAGLARRCEVQVSY 299 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP+SV V+++GT +P+ I V++ F RP I+ L+L + + KTAAYG Sbjct: 300 AIGVAEPVSVMVETFGTATVPEERIALAVRKTFGLRPREITEYLNLLR--PIYQKTAAYG 357 Query: 1025 HFGRDDADFTWEVVKPLK 1078 HFGR + +FTWE V+ K Sbjct: 358 HFGRTEKEFTWERVEEKK 375
>Q9I5Z0:METK_PSEAE S-adenosylmethionine synthetase - Pseudomonas aeruginosa| Length = 396 Score = 299 bits (765), Expect = 2e-80 Identities = 179/397 (45%), Positives = 236/397 (59%), Gaps = 64/397 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E +FTSESV+EGHPDK+ DQ+SDAVLDA +A+D ++VACET+ KT + ++ GE+TT Sbjct: 2 SEYSVFTSESVSEGHPDKIADQISDAVLDAIIAKDKYARVACETLVKTGVAIIAGEVTTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VD E++VR +IG+ S DVG D C VL I +QS DI QGV +PE+ GA Sbjct: 62 AWVDLEELVRKVIIDIGYDSSDVGFDGATCGVLNIIGKQSVDINQGVD---RAKPEDQGA 118 Query: 455 GDQGIMFGYATDETPELMP----LSH---------------------------------- 520 GDQG+MFGYA++ET LMP SH Sbjct: 119 GDQGLMFGYASNETDVLMPAPICFSHRLVERQAEARKSGLLPWLRPDAKSQVTCRYEGGK 178 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E +IK V+PA+ L ++T FH+NP+G FVIGGP Sbjct: 179 VVGIDAVVLSTQHNPEVSYNDLRDGVMELIIKQVLPAELLHKDTQFHINPTGNFVIGGPV 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+D+Y KDP+KVDRS AY R AK+I+A+GLA RC + Sbjct: 239 GDCGLTGRKIIVDSYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAERCEI 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV +P S+ ++++GTGK+ D +I++LV+E+FD RP I+ LDL + T Sbjct: 299 QVSYAIGVAQPTSISINTFGTGKVSDEKIVQLVREHFDLRPYAITKMLDLLH--PMYQPT 356 Query: 1013 AAYGHFGRD------DAD----FTWEVVKPLKFDKAS 1093 AAYGHFGR D D FTWE K DKA+ Sbjct: 357 AAYGHFGRHPFELTVDGDTFTAFTWE-----KTDKAA 388
>Q88D60:METK_PSEPK S-adenosylmethionine synthetase - Pseudomonas putida (strain KT2440)| Length = 396 Score = 298 bits (763), Expect = 4e-80 Identities = 173/386 (44%), Positives = 229/386 (59%), Gaps = 64/386 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDAVLDA +AQD ++VACET+ KT + ++ GE+TT Sbjct: 2 SEYSLFTSESVSEGHPDKIADQISDAVLDAIIAQDKYARVACETLVKTGVAIIAGEVTTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A VD E +VR +IG+ S DVG D C V+ I +QS DIAQGV +PE+ GA Sbjct: 62 AWVDLEDLVRKVIIDIGYNSSDVGFDGATCAVMNIIGKQSVDIAQGVD---RSKPEDQGA 118 Query: 455 GDQGIMFGYATDETPELMP----LSH---------------------------------- 520 GDQG+MFGYA++ET LMP SH Sbjct: 119 GDQGLMFGYASNETEVLMPAPICFSHRLVERQAEARKSGLLPWLRPDAKSQVTCRYENGK 178 Query: 521 -------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ L + E ++K +PA+ L + T +H+NP+G F+IGGP Sbjct: 179 VVGIDAVVLSTQHNPEVSQKDLQEAVMELIVKHTLPAELLHKGTQYHINPTGNFIIGGPV 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+D+Y KDP+KVDRS AY R AK+I+A+GLA RC + Sbjct: 239 GDCGLTGRKIIVDSYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAERCEI 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV +P S+ ++++GTGK+ D +I++LV+E FD RP I+ LDL + +T Sbjct: 299 QVSYAIGVAQPTSISINTFGTGKVSDDKIIQLVRECFDLRPYAITTMLDLLH--PMYQET 356 Query: 1013 AAYGHFGR--------DD--ADFTWE 1060 AAYGHFGR DD FTWE Sbjct: 357 AAYGHFGRTPQQKTVGDDTFTTFTWE 382
>Q9RL99:METK_RICTY S-adenosylmethionine synthetase - Rickettsia typhi| Length = 382 Score = 298 bits (762), Expect = 5e-80 Identities = 165/375 (44%), Positives = 218/375 (58%), Gaps = 54/375 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E F+FTSESV+EGHPDK+ DQ+SDAVLD L D + +VACET T +V+V GEITT Sbjct: 2 ENFVFTSESVSEGHPDKIADQISDAVLDEILKHDPNGRVACETFVTTGLVLVGGEITTNT 61 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 VD E++VR+ IG+ + G D C V+ +I +QSPDIA G+ EE+GAG Sbjct: 62 YVDIEQVVRNKIHEIGYNNPSYGFDGSCCAVISSIVKQSPDIAMGIDN---ANEEEIGAG 118 Query: 458 DQGIMFGYATDETPELMPL----------------------------------------- 514 DQ ++FGYA +ET LMP Sbjct: 119 DQEMVFGYACNETKSLMPAPIYYAHLLMKRQAYLRKQNILSWLRPDAKSQVTLRYENNKP 178 Query: 515 ----SHVLATKLGARLK---------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 S VL+T+ ++ E +IKP +P L ++T + +NP+GRFVIGGP Sbjct: 179 IVIDSVVLSTQHHPEIQQKDLIEAVIEEIIKPTLPTHLLHKDTKYLINPTGRFVIGGPVA 238 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII+D+Y KDPTK+DRS AY+AR AK+I+ SGLA RC +Q Sbjct: 239 DCGLTGRKIIVDSYGGMAKHGGGCFSGKDPTKIDRSAAYMARYIAKNIVGSGLADRCEIQ 298 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 ISYAIGV P+SV+ +++GT K+ + + KL+ E+FD RPG I NL L + KTA Sbjct: 299 ISYAIGVASPVSVYAETFGTSKLSNEQTTKLITEHFDMRPGKIIKNLKLHT--QCYQKTA 356 Query: 1016 AYGHFGRDDADFTWE 1060 +YGHFGR+D +FTWE Sbjct: 357 SYGHFGREDENFTWE 371
>Q5P2V5:METK_AZOSE S-adenosylmethionine synthetase - Azoarcus sp. (strain EbN1)| (Aromatoleum aromaticum (strain EbN1)) Length = 388 Score = 298 bits (762), Expect = 5e-80 Identities = 171/395 (43%), Positives = 231/395 (58%), Gaps = 54/395 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 ++ +LFTSESV+EGHPDK+ DQVSD VLDA LA D ++VACET+ T +V++ GEITT Sbjct: 2 SKEYLFTSESVSEGHPDKVADQVSDGVLDAILATDPQARVACETLVSTGLVVISGEITTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 A +Y +I ++ R IG+ + D+G D C VL I +QS DIAQGV+ + GA Sbjct: 62 AHPNYREIAQEVIRRIGYDNSDIGFDYKSCAVLAAINRQSADIAQGVN-EGEGLDLDQGA 120 Query: 455 GDQGIMFGYATDETPELMPLSHVLATKL-------------------------------- 538 GDQG+MFGYA +ETP L+PL A ++ Sbjct: 121 GDQGLMFGYACNETPSLIPLPIYYAHRIMQRQSELRKDGRLNWLRPDAKSQLTVRYVDGK 180 Query: 539 ------------------GARLKEHVIKPVI----PAKYLDENTIFHLNPSGRFVIGGPH 652 A++ E VI+ +I P+ + + +NP+GRFVIGGPH Sbjct: 181 PVAIDTVVVSTQHSPEVSHAQITELVIEEIIKPVLPSALMQGEVRYLINPTGRFVIGGPH 240 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA RC V Sbjct: 241 GDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSAAYAGRWVAKNIVAAGLADRCEV 300 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q++YAIGV P+S+ ++++GTG+I D +I++LV+ +FD RP I L+L + + KT Sbjct: 301 QVAYAIGVARPVSMMIETFGTGRITDEKIVELVQRHFDLRPKAIIQELNLLR--PIYGKT 358 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA*EQDITL 1117 AAYGHFGRD+ +FTWE DKA+A D L Sbjct: 359 AAYGHFGRDEPEFTWEAT-----DKAAALRADAGL 388
>Q8EP05:METK_OCEIH S-adenosylmethionine synthetase - Oceanobacillus iheyensis| Length = 398 Score = 297 bits (761), Expect = 7e-80 Identities = 170/387 (43%), Positives = 223/387 (57%), Gaps = 63/387 (16%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MAA LFTSESV EGHPDK+ DQ+SDA+LD L +D +++VACET T +V+V GEI+ Sbjct: 1 MAANRRLFTSESVTEGHPDKMSDQISDAILDEILKKDPNARVACETTVTTGLVLVSGEIS 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--- 439 T VD +VR+T + IG+ G D + C VL I++QS DIA GV+ R Sbjct: 61 TSTYVDIPALVRETVKEIGYTRAKYGFDFETCAVLTAIDEQSADIAGGVNQALEARQGKM 120 Query: 440 -----EEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLKE------------ 556 + +GAGDQG+MFGYA DET ELMPL +H L+ +L KE Sbjct: 121 SEEEIDAIGAGDQGLMFGYACDETEELMPLPISLAHQLSKRLADVRKEGIVDYLRPDGKT 180 Query: 557 ---------------------------------------HVIKPVIPAKYLDENTIFHLN 619 VI+ V+P++ LD+ T + +N Sbjct: 181 QVTVEYDENDKPERIDTIVISTQHHSEIQNEQIERDMIEKVIQAVVPSELLDDKTKYFIN 240 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+GRFVIGGP GD GLTGRKII+DTY KD TKVDRS AY AR AK+I Sbjct: 241 PTGRFVIGGPQGDVGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNI 300 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLD 979 +A+GLA+ C VQ++YAIGV +P+S+ V+++GTGK+ + +++ V+E FD RP I LD Sbjct: 301 VAAGLAKSCEVQLAYAIGVAQPVSIAVNTFGTGKVSEDRLVEAVRELFDLRPAGIIRMLD 360 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWE 1060 L+K + TAAYGHFGR D F WE Sbjct: 361 LRK--PIYKNTAAYGHFGRKDILFPWE 385
>Q2SLT3:METK_HAHCH S-adenosylmethionine synthetase - Hahella chejuensis (strain KCTC| 2396) Length = 386 Score = 297 bits (761), Expect = 7e-80 Identities = 175/388 (45%), Positives = 227/388 (58%), Gaps = 54/388 (13%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E +FTSESV+EGHPDK+ DQ+SDA+LDA + D +++VA ET+ KT M ++ GE+ T Sbjct: 2 SEYSIFTSESVSEGHPDKMADQISDAILDAIIKDDPNARVAVETLVKTGMAVIAGEVRTN 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 VD E IVR +IG+ S DVG D C VL I +QS DIA GV K ++GA Sbjct: 62 TYVDLEDIVRSVILDIGYNSSDVGFDGASCAVLNAIGKQSGDIAMGVDEASEK---DLGA 118 Query: 455 GDQGIMFGYATDETPELMPL----SH---------------------------------- 520 GDQG+MFGYAT+ET LMP SH Sbjct: 119 GDQGLMFGYATNETDVLMPAPIYYSHRLVERQAYLRKNSILPWLRPDAKSQVTLRYENGK 178 Query: 521 -------VLATKLGARLK---------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 VL+T+ +K E +IK V+P ++L NT +H+NP+G+F+IGGP Sbjct: 179 PVAVEAVVLSTQHTPDVKQSDIREAVMEEIIKHVLPEEWLHSNTQYHINPTGQFIIGGPV 238 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD GLTGRKII+DTY KDP+KVDRS AY R AK+I+ASGLA +C + Sbjct: 239 GDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVASGLAAKCEI 298 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIGV EP S+ V+++GTGKI D +I LV+E+FD RP + LDLK+ R T Sbjct: 299 QVSYAIGVSEPTSISVNTFGTGKISDDKIATLVREHFDLRPRGLIDMLDLKRPIYR--PT 356 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFDKASA 1096 A+YGHFGR F+WE + DKA A Sbjct: 357 ASYGHFGRTGDSFSWE-----RTDKADA 379
>Q91X83:METK1_MOUSE S-adenosylmethionine synthetase isoform type-1 - Mus musculus (Mouse)| Length = 396 Score = 297 bits (761), Expect = 7e-80 Identities = 172/382 (45%), Positives = 225/382 (58%), Gaps = 56/382 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 F+FTSESV EGHPDK+CDQ+SDAVLDA L QD ++KVACETV KT MV++ GEIT+ A V Sbjct: 19 FMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSVAMV 78 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLV-------------NIEQQSPDIAQG---- 412 DY+++VRDT ++IG+ G D C VLV ++++ D+ G Sbjct: 79 DYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGL 138 Query: 413 VHGHFTKRPEE----------------VGAGDQGIMFGYATDETPEL------------- 505 + G+ T EE G++ D ++ Sbjct: 139 MFGYATDETEECMPLTIVLAHKLNTRIADLRRSGVLPWLRPDSKTQVTVQYMQDNGAVIP 198 Query: 506 -------MPLSH---VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 + + H + + LKE VIK V+PAKYLDE+T++HL PSGRFVIGGP G Sbjct: 199 VRIHTIVISVQHNEDITLEAMQEALKEQVIKAVVPAKYLDEDTVYHLQPSGRFVIGGPQG 258 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 DAG+TGRKII+DTY KD TKVDRS AY AR AKS++ +GL RR +VQ Sbjct: 259 DAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQ 318 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 +SYAIGV EPLS+ + +YGT +RE+L++V +NFD RPG+I +LDLKK + KTA Sbjct: 319 VSYAIGVAEPLSISIFTYGTSNKTERELLEVVNKNFDLRPGVIVRDLDLKK--PIYQKTA 376 Query: 1016 AYGHFGRDDADFTWEVVKPLKF 1081 YGHFGR ++F WEV K L F Sbjct: 377 CYGHFGR--SEFPWEVPKKLVF 396
>P57897:METK_PASMU S-adenosylmethionine synthetase - Pasteurella multocida| Length = 384 Score = 296 bits (757), Expect = 2e-79 Identities = 175/385 (45%), Positives = 226/385 (58%), Gaps = 54/385 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQ+SDAVLD L QD ++VACET KT M +V GEITT A V Sbjct: 4 YLFTSESVSEGHPDKIADQISDAVLDEILKQDPKARVACETYVKTGMALVGGEITTSAWV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 D E + R +IG+ D+G D C VL I +QS DI QGV + P + GAGDQ Sbjct: 64 DIENLTRQVICDIGYKHSDMGFDGHSCAVLNAIGKQSSDINQGVD---RENPLDQGAGDQ 120 Query: 464 GIMFGYATDETPELMPLSH----------------------------------------- 520 GIMFGYAT+ET LMP + Sbjct: 121 GIMFGYATNETEVLMPAAITYAHRLMERQAKVRKEGTLPWLRPDAKSQVTLKYEDHKIVG 180 Query: 521 ----VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDA 661 VL+T+ L + E +IKPV+PA++L + T + +NP+GRFVIGGP GD Sbjct: 181 VDAVVLSTQHCDSISQHDLHEAVMEEIIKPVLPAEWLSKETKYFINPTGRFVIGGPMGDC 240 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+S Sbjct: 241 GLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQLS 300 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIGV +P S+ V+++GTGK+ + ++ LV+E FD RP + LDL + R +TAAY Sbjct: 301 YAIGVADPTSIMVETFGTGKVANELLVALVREFFDLRPYGLIKMLDLIQPIYR--ETAAY 358 Query: 1022 GHFGRDDADFTWEVVKPLKFDKASA 1096 GHFGR+ F WE V + +A+A Sbjct: 359 GHFGRE--QFPWEKVDRAEELRAAA 381
>P13444:METK1_RAT S-adenosylmethionine synthetase isoform type-1 - Rattus norvegicus| (Rat) Length = 397 Score = 295 bits (756), Expect = 2e-79 Identities = 174/383 (45%), Positives = 224/383 (58%), Gaps = 57/383 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 F+FTSESV EGHPDK+CDQ+SDAVLDA L QD ++KVACETV KT MV++ GEIT+ A + Sbjct: 19 FMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMI 78 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLV-------------NIEQQSPDIAQG---- 412 DY+++VRDT ++IG+ G D C VLV ++++ D+ G Sbjct: 79 DYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGL 138 Query: 413 VHGHFTKRPEE----------------VGAGDQGIM------------FGYATDETPELM 508 + G+ T EE G++ Y D + Sbjct: 139 MFGYATDETEECMPLTIVLAHKLNTRMADLRRSGVLPWLRPDSKTQVTVQYVQDNGAVIP 198 Query: 509 PLSHVLATK-----------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 H + + LKE VIK V+PAKYLDE+TI+HL PSGRFVIGGP G Sbjct: 199 VRVHTIVISVQHNEDITLEAMREALKEQVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQG 258 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 DAG+TGRKII+DTY KD TKVDRS AY AR AKS++ +GL RR +VQ Sbjct: 259 DAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQ 318 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDR-EILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 +SYAIGV EPLS+ + +YGT K +R E+L++V +NFD RPG+I +LDLKK + KT Sbjct: 319 VSYAIGVAEPLSISIFTYGTSKKTERDELLEVVNKNFDLRPGVIVRDLDLKK--PIYQKT 376 Query: 1013 AAYGHFGRDDADFTWEVVKPLKF 1081 A YGHFGR ++F WEV K L F Sbjct: 377 ACYGHFGR--SEFPWEVPKKLVF 397
>Q00266:METK1_HUMAN S-adenosylmethionine synthetase isoform type-1 - Homo sapiens (Human)| Length = 395 Score = 295 bits (755), Expect = 3e-79 Identities = 170/382 (44%), Positives = 226/382 (59%), Gaps = 56/382 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 F+FTSESV EGHPDK+CDQ+SDAVLDA L QD ++KVACETV KT MV++ GEIT+ A V Sbjct: 18 FMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMV 77 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLV-------------NIEQQSPDIAQG---- 412 DY+++VRDT ++IG+ G D C VLV ++++ D+ G Sbjct: 78 DYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGL 137 Query: 413 VHGHFTKRPEE----------------VGAGDQGIMFGYATDETPEL------------- 505 + G+ T EE G++ D ++ Sbjct: 138 MFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIP 197 Query: 506 -------MPLSH---VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 + + H + ++ LKE VI+ V+PAKYLDE+T++HL PSGRFVIGGP G Sbjct: 198 VRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDTVYHLQPSGRFVIGGPQG 257 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 DAG+TGRKII+DTY KD TKVDRS AY AR AKS++ +GL RR +VQ Sbjct: 258 DAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQ 317 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 +SYAIGV EPLS+ + +YGT + +RE+L +V +NFD RPG+I +LDLKK + KTA Sbjct: 318 VSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKK--PIYQKTA 375 Query: 1016 AYGHFGRDDADFTWEVVKPLKF 1081 YGHFGR ++F WEV + L F Sbjct: 376 CYGHFGR--SEFPWEVPRKLVF 395
>Q2KJC6:METK1_BOVIN S-adenosylmethionine synthetase isoform type-1 - Bos taurus (Bovine)| Length = 396 Score = 295 bits (755), Expect = 3e-79 Identities = 174/384 (45%), Positives = 225/384 (58%), Gaps = 58/384 (15%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 F+FTSESV EGHPDK+CDQ+SDAVLDA L QD ++KVACETV KT MV++ GEIT+ A V Sbjct: 19 FMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMV 78 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLV-------------NIEQQSPDIAQG---- 412 DY+++VR+T ++IG+ G D C VLV ++++ D+ G Sbjct: 79 DYQRVVRETIQHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGL 138 Query: 413 VHGHFTKRPEEVGAGDQGIMFGYATD----------ETPELMPLSHVLAT---------- 532 + G+ T EE IM + + + P L P S T Sbjct: 139 MFGYATDETEE--CMPLTIMLAHRLNARMAELRRSGQLPWLQPDSKTQVTVQYTQDNGAV 196 Query: 533 ---------------------KLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGP 649 + LKE VI+ V+PA+YLDE+TI+HL PSGRFVIGGP Sbjct: 197 IPMRVHTVVISVQHNEDITLEDMRRALKEQVIRAVVPARYLDEDTIYHLQPSGRFVIGGP 256 Query: 650 HGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCI 829 GDAG+TGRKII+DTY KD TKVDRS AY AR AKS++ +GL RR + Sbjct: 257 QGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVL 316 Query: 830 VQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIK 1009 VQ+SYAIGV EPLS+ + +YGT + +RE+L +V +NFD RPG+I +LDLKK + K Sbjct: 317 VQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVNKNFDLRPGVIVRDLDLKK--PIYQK 374 Query: 1010 TAAYGHFGRDDADFTWEVVKPLKF 1081 TA YGHFGR ++F WEV K L F Sbjct: 375 TACYGHFGR--SEFPWEVPKKLVF 396
>Q8DQH0:METK_STRR6 S-adenosylmethionine synthetase - Streptococcus pneumoniae (strain| ATCC BAA-255 / R6) Length = 396 Score = 295 bits (754), Expect = 4e-79 Identities = 173/396 (43%), Positives = 229/396 (57%), Gaps = 62/396 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D ++ VA ET T V V GEI+T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAETAVYTGSVHVFGEISTN 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH------GHFTKR 436 A VD ++VRDT IG+ + + G A+ V ++ +QSPDIAQGV+ G+ + Sbjct: 62 AYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSPDIAQGVNEALEVRGNADQD 121 Query: 437 PEE-VGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK---------------- 553 P + +GAGDQG+MFG+A DET ELMPL SH L +L K Sbjct: 122 PLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRLAELRKSGEISYLRPDAKSQVT 181 Query: 554 -----------------------------------EHVIKPVIPAKYLDENTIFHLNPSG 628 + VIK VIP+ YLD+ T F +NP+G Sbjct: 182 VEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDKVIKEVIPSSYLDDKTKFFINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I+A+ Sbjct: 242 RFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLA++ VQ++YAIGV +P+SV +D++GTG + + ++ K ++ FD RP I LDLK+ Sbjct: 302 GLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVAESQLEKAARQIFDLRPAGIIQMLDLKR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 R +T+AYGH GR D D WE + DK A Sbjct: 362 PIYR--QTSAYGHMGRTDIDLPWE-----RLDKVDA 390
>O83772:METK_TREPA S-adenosylmethionine synthetase - Treponema pallidum| Length = 396 Score = 294 bits (752), Expect = 7e-79 Identities = 175/377 (46%), Positives = 218/377 (57%), Gaps = 56/377 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ETF FTSESV+EGHPDKLCDQ+SDAVLDACL+QD S VACET T+++++ GEI+T+A Sbjct: 2 ETF-FTSESVSEGHPDKLCDQISDAVLDACLSQDPHSCVACETFASTSLILIGGEISTRA 60 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKR-PEEVGA 454 ++ +I RD +IG++S DVGLDA VL QSPDIAQGVHG K GA Sbjct: 61 HINLTQIARDVAADIGYVSADVGLDAASMAVLDMTHHQSPDIAQGVHGAGLKEFAGSQGA 120 Query: 455 GDQGIMFGYATDETPELMPL-----------------------------SHVLATKLGAR 547 GDQGIMFG+A ETPE MP S V G R Sbjct: 121 GDQGIMFGFACRETPEFMPAPLMCAHAVVRYAATLRHERRVPWLRPDAKSQVTVQYEGHR 180 Query: 548 ---------------------LKEHVIKPVI-----PAKYLDENTIFHLNPSGRFVIGGP 649 ++E +I+ ++ P LDENT F +NP+GRFVIGGP Sbjct: 181 PVRISAVVFSQQHDPSPSYETIRETLIEEIVRPALAPTGLLDENTRFFINPTGRFVIGGP 240 Query: 650 HGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCI 829 GD GLTGRKII+DTY KD +KVDRS AY+AR AK+I+A+ LA RC Sbjct: 241 FGDTGLTGRKIIVDTYGGMGRHGGGSFSGKDASKVDRSAAYMARYIAKNIVAADLAERCE 300 Query: 830 VQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIK 1009 VQ++YAIGVP P+S+ ++++GT + + I VKE FD P I LDL R+ Sbjct: 301 VQLAYAIGVPYPVSLRIETFGTARASESHITHAVKEIFDLTPAGIVRTLDL--CAPRYRS 358 Query: 1010 TAAYGHFGRDDADFTWE 1060 TA YGHFGR+ F WE Sbjct: 359 TAVYGHFGRE--QFPWE 373
>Q8DT23:METK_STRMU S-adenosylmethionine synthetase - Streptococcus mutans| Length = 397 Score = 294 bits (752), Expect = 7e-79 Identities = 174/384 (45%), Positives = 222/384 (57%), Gaps = 62/384 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA L QD D+ VA ET T V V GEI+T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAVLVQDPDAHVAAETAVYTGSVHVFGEISTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH------GHFTKR 436 A VD ++VRDT IG+ G A+ V ++ +QSPDIAQGV+ GH + Sbjct: 62 AYVDINRVVRDTIAEIGYTDTAYGFSAETVGVHPSLVEQSPDIAQGVNEALEVRGHHEQD 121 Query: 437 PEE-VGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK---------------- 553 + +GAGDQG+MFG+A DETPELMPL +H L KL K Sbjct: 122 DLDLIGAGDQGLMFGFAVDETPELMPLPISLAHRLVRKLAELRKSGEIAYLRPDAKSQVT 181 Query: 554 -----------------------------------EHVIKPVIPAKYLDENTIFHLNPSG 628 E VIK VIPA+YLD T + +NP+G Sbjct: 182 VEYDENDKPVRVDTVVISTQHDPEATNEQIHRDVIEKVIKAVIPAEYLDAKTKYLINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I+A+ Sbjct: 242 RFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSASYAARYIAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLA++ VQ++YAIGV +P+SV VD++GT + + ++ + V++ FD RP I LDLK+ Sbjct: 302 GLAKKAEVQLAYAIGVAQPVSVRVDTFGTALVAESKLEQAVRQIFDLRPAGIIKMLDLKR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWE 1060 R +TAAYGH GR D D WE Sbjct: 362 PIYR--QTAAYGHVGRTDIDLPWE 383
>Q9CEE0:METK_LACLA S-adenosylmethionine synthetase - Lactococcus lactis subsp. lactis| (Streptococcus lactis) Length = 399 Score = 293 bits (751), Expect = 9e-79 Identities = 174/386 (45%), Positives = 222/386 (57%), Gaps = 64/386 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LAQD + VACETV T V V GEI+T Sbjct: 2 SEKHLFTSESVSEGHPDKVADQISDAILDAILAQDPHAHVACETVVYTGTVNVFGEISTS 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH---------GHF 427 A VD +VR+T + IG+ + G D V V++ +QS DIAQGV+ G Sbjct: 62 AYVDIAHVVRETIKKIGYTDSENGFDYKSVGVHVSLVEQSSDIAQGVNEAEEVRDKNGQL 121 Query: 428 TKRPEEVGAGDQGIMFGYATDETPELMPL----SHVLATKLG------------------ 541 + +GAGDQG+MFG+AT+ET E MPL SH L KL Sbjct: 122 VDPLDLIGAGDQGMMFGFATNETAEYMPLAISLSHKLVKKLADLRKSGEISYLRPDAKSQ 181 Query: 542 --------------------------ARLKE-------HVIKPVIPAKYLDENTIFHLNP 622 AR +E VIK VIPA+ LD+ T + +NP Sbjct: 182 VTVEYDDNGKAKRIDTVVISTQHAASARNEEIHDDVINKVIKAVIPAELLDDETKYFINP 241 Query: 623 SGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSII 802 +GRFVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I+ Sbjct: 242 TGRFVIGGPQGDSGLTGRKIIVDTYGGYAPHGGGAFSGKDATKVDRSASYAARYVAKNIV 301 Query: 803 ASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDL 982 A+GLA + +Q+SYAIGV P S+ VD++GTGK+ D E+L +++ FD RP I LDL Sbjct: 302 AAGLAEKAQIQLSYAIGVATPTSINVDTFGTGKVSDDELLAAIRKVFDLRPAGIIQMLDL 361 Query: 983 KKGGNRFIKTAAYGHFGRDDADFTWE 1060 + + +TAAYGHFGR D + WE Sbjct: 362 LR--PIYGQTAAYGHFGRTDVELPWE 385
>Q48SU7:METK_STRPM S-adenosylmethionine synthetase - Streptococcus pyogenes serotype M28| Length = 398 Score = 293 bits (749), Expect = 2e-78 Identities = 170/383 (44%), Positives = 221/383 (57%), Gaps = 61/383 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D ++ VA ET T V V GEI+TK Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTGSVHVFGEISTK 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE--- 445 A +D ++VRDT IG+ + G A+ V ++ +QS DIAQGV+ R + Sbjct: 62 AYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSGDIAQGVNEALESREGDTDD 121 Query: 446 ---VGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK----------------- 553 +GAGDQG+MFG+A +ETPELMPL SH L +L K Sbjct: 122 LSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLAELRKSGEISYLRPDAKSQVTV 181 Query: 554 ----------------------------------EHVIKPVIPAKYLDENTIFHLNPSGR 631 E VIK VIPA YLD++T F +NP+GR Sbjct: 182 EYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGR 241 Query: 632 FVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASG 811 FVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+++A+G Sbjct: 242 FVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAAG 301 Query: 812 LARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKG 991 LA + VQ++YAIGV +P+SV VD++GT +P+ + V++ FD RP I LDLK+ Sbjct: 302 LATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPAGIIQMLDLKR- 360 Query: 992 GNRFIKTAAYGHFGRDDADFTWE 1060 + +TAAYGH GR D D WE Sbjct: 361 -PIYKQTAAYGHMGRTDIDLPWE 382
>Q97RN9:METK_STRPN S-adenosylmethionine synthetase - Streptococcus pneumoniae| Length = 396 Score = 292 bits (747), Expect = 3e-78 Identities = 172/396 (43%), Positives = 228/396 (57%), Gaps = 62/396 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D ++ VA ET T V V GEI+T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAETAVYTGSVHVFGEISTN 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH------GHFTKR 436 A VD ++VRDT IG+ + + G A+ V ++ +QSPDIAQGV+ G+ + Sbjct: 62 AYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSPDIAQGVNEALEVRGNADQD 121 Query: 437 PEE-VGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK---------------- 553 P + +GAGDQG+MFG+A DET ELMPL SH L +L K Sbjct: 122 PLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRLAELRKSGEISYLRPDAKSQVT 181 Query: 554 -----------------------------------EHVIKPVIPAKYLDENTIFHLNPSG 628 + VIK VIP+ YLD+ T F +NP+G Sbjct: 182 VEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDKVIKEVIPSSYLDDKTKFFINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I+A+ Sbjct: 242 RFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 LA++ VQ++YAIGV +P+SV +D++GTG + + ++ K ++ FD RP I LDLK+ Sbjct: 302 DLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVAESQLEKAARQIFDLRPAGIIQMLDLKR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKASA 1096 R +T+AYGH GR D D WE + DK A Sbjct: 362 PIYR--QTSAYGHMGRTDIDLPWE-----RLDKVDA 390
>Q5SHT8:METK_THET8 S-adenosylmethionine synthetase - Thermus thermophilus (strain HB8 /| ATCC 27634 / DSM 579) Length = 395 Score = 291 bits (746), Expect = 4e-78 Identities = 171/380 (45%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 L TSESV EGHPDKL D++SDA+LDA +AQD ++VA ET+ T +V V GEITT+ VD Sbjct: 6 LVTSESVTEGHPDKLADRISDAILDALIAQDKKARVAAETLVTTGLVFVAGEITTEGYVD 65 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHF-------TKRPEE 445 +VR T R +G+ G DAD C VL I++QSPDIA GV+ + T + Sbjct: 66 IPNLVRKTVREVGYTRAKYGFDADTCAVLTAIDEQSPDIAGGVNLSYEWRVLKSTDPLDR 125 Query: 446 VGAGDQGIMFGYATDETPELMPLSHVLATKLGAR-------------------------- 547 VGAGDQG+MFGYATDETPELMPL LA +L R Sbjct: 126 VGAGDQGLMFGYATDETPELMPLPITLAHRLTMRLAEVRKTGLLPYLRPDGKAQVTVVYE 185 Query: 548 ------------------------LKEHVIKPV----IPAKYL-DENTIFHLNPSGRFVI 640 L+E +I+ V IP +YL D T + +NPSGRF++ Sbjct: 186 GDKPLYVKTVVVSAQHSPEVEQEQLREDLIREVVRQAIPPEYLKDGETEYLINPSGRFIL 245 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGPH D GLTGRKII+DTY KDPTKVDRS +Y AR AK+I+A+GLAR Sbjct: 246 GGPHADTGLTGRKIIVDTYGGAVPHGGGAFSGKDPTKVDRSASYYARYMAKNIVAAGLAR 305 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 R +V+++YAIG P+S+ V+++GTG +PD ++ ++ K+ FD RP I LDL + Sbjct: 306 RALVELAYAIGKARPVSLRVETFGTGVLPDEKLTEIAKKVFDPRPLAIIEELDLLR--PI 363 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + T+AYGHFGR F WE Sbjct: 364 YTPTSAYGHFGR--PGFPWE 381
>Q72I53:METK_THET2 S-adenosylmethionine synthetase - Thermus thermophilus (strain HB27 /| ATCC BAA-163 / DSM 7039) Length = 395 Score = 291 bits (746), Expect = 4e-78 Identities = 171/380 (45%), Positives = 221/380 (58%), Gaps = 62/380 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 L TSESV EGHPDKL D++SDA+LDA +AQD ++VA ET+ T +V V GEITT+ VD Sbjct: 6 LVTSESVTEGHPDKLADRISDAILDALIAQDKKARVAAETLVTTGLVFVAGEITTEGYVD 65 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHF-------TKRPEE 445 +VR T R +G+ G DAD C VL I++QSPDIA GV+ + T + Sbjct: 66 IPNLVRKTVREVGYTRAKYGFDADTCAVLTAIDEQSPDIAGGVNLSYEWRVLKSTDPLDR 125 Query: 446 VGAGDQGIMFGYATDETPELMPLSHVLATKLGAR-------------------------- 547 VGAGDQG+MFGYATDETPELMPL LA +L R Sbjct: 126 VGAGDQGLMFGYATDETPELMPLPITLAHRLTMRLAEVRKTGLLPYLRPDGKAQVTVVYE 185 Query: 548 ------------------------LKEHVIKPV----IPAKYL-DENTIFHLNPSGRFVI 640 L+E +I+ V IP +YL D T + +NPSGRF++ Sbjct: 186 GDKPLYVKTVVVSAQHSPEVEQEQLREDLIREVVRQAIPPEYLKDGETEYLINPSGRFIL 245 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGPH D GLTGRKII+DTY KDPTKVDRS +Y AR AK+I+A+GLAR Sbjct: 246 GGPHADTGLTGRKIIVDTYGGAVPHGGGAFSGKDPTKVDRSASYYARYMAKNIVAAGLAR 305 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 R +V+++YAIG P+S+ V+++GTG +PD ++ ++ K+ FD RP I LDL + Sbjct: 306 RALVELAYAIGKARPVSLRVETFGTGVLPDEKLTEIAKKVFDPRPLAIIEELDLLR--PI 363 Query: 1001 FIKTAAYGHFGRDDADFTWE 1060 + T+AYGHFGR F WE Sbjct: 364 YTPTSAYGHFGR--PGFPWE 381
>Q99Z77:METK_STRP1 S-adenosylmethionine synthetase - Streptococcus pyogenes serotype M1| Length = 398 Score = 291 bits (745), Expect = 5e-78 Identities = 169/383 (44%), Positives = 220/383 (57%), Gaps = 61/383 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D ++ VA ET T V V GEI+T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTGSVHVFGEISTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE--- 445 A +D ++VRDT IG+ + G A+ V ++ +QS DIAQGV+ F R + Sbjct: 62 AYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSGDIAQGVNEAFESREGDTDD 121 Query: 446 ---VGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK----------------- 553 +GAGDQG+MFG+A +ETPELMPL SH L +L K Sbjct: 122 LSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLAELRKSGEISYLRPDAKSQVTV 181 Query: 554 ----------------------------------EHVIKPVIPAKYLDENTIFHLNPSGR 631 E VIK VIPA YLD++T F +NP+GR Sbjct: 182 EYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGR 241 Query: 632 FVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASG 811 FVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+++A+G Sbjct: 242 FVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAAG 301 Query: 812 LARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKG 991 L + VQ++YAIGV +P+SV VD++GT +P+ + V++ FD RP I LDLK+ Sbjct: 302 LVTKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPAGIIQMLDLKR- 360 Query: 992 GNRFIKTAAYGHFGRDDADFTWE 1060 + +TAAYGH GR D D WE Sbjct: 361 -PIYKQTAAYGHMGRTDIDLPWE 382
>Q6AF79:METK_LEIXX S-adenosylmethionine synthetase - Leifsonia xyli subsp. xyli| Length = 397 Score = 291 bits (744), Expect = 6e-78 Identities = 173/384 (45%), Positives = 219/384 (57%), Gaps = 62/384 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 A+ LFTSESV EGHPDK+CDQ+SD++LDA LA D S+VA ET+ T +V V GE+TTK Sbjct: 2 ADLRLFTSESVTEGHPDKICDQISDSILDALLAVDEHSRVAVETLVTTGLVHVAGEVTTK 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV-- 448 V+ +VRDT IG+ S DV D +C V V+I QSPDIAQGV R E Sbjct: 62 GYVEIPALVRDTIVEIGYDSSDVSFDGTQCGVSVSIGAQSPDIAQGVDNALETRSERSQD 121 Query: 449 -----GAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK---------------- 553 GAGDQGIMFG+AT ETP+ MPL +H LA +L A K Sbjct: 122 DLDRQGAGDQGIMFGFATTETPQYMPLPIWLAHRLAERLAAVRKDGTLGYLRPDGKTQVT 181 Query: 554 ----------------------------------EHVIKPVIPAKYLDENTIFHL-NPSG 628 E VI+PV+ A ++ + I L NP+G Sbjct: 182 IGYEGYVPKSVQTVVLSTQHARDIPSQQLRADVIEQVIEPVMHAAGVETSHIRTLINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RF IGGP GDAGLTGRKII+DTY KDP+KVDRS AY R AK+ +A+ Sbjct: 242 RFEIGGPKGDAGLTGRKIIVDTYGGASRHGGGAFSGKDPSKVDRSAAYALRWVAKNAVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLA R VQI+YAIG P+ ++V+++GT +PD I+ ++E FD RP I+ +LDL + Sbjct: 302 GLADRLEVQIAYAIGKAAPVGLYVETFGTAHVPDERIIHAIREVFDLRPAAIARDLDLLR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWE 1060 + +TA YGHFGR+ DFTWE Sbjct: 362 --PIYARTATYGHFGRELPDFTWE 383
>Q7WYG5:METK_AMOPS S-adenosylmethionine synthetase - Amoeba proteus symbiotic bacterium| Length = 381 Score = 291 bits (744), Expect = 6e-78 Identities = 172/384 (44%), Positives = 224/384 (58%), Gaps = 54/384 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 +FTSESV+EGHPDK+ DQ+SDA+LDA LA+D ++VACET KT MV+V GEITT A VD Sbjct: 5 VFTSESVSEGHPDKIADQISDAILDAILAKDPLARVACETFVKTGMVLVGGEITTSAWVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 E I R+ ++IG+ S D+G D C VL I +QS DIAQGV TK +GAGDQG Sbjct: 65 VETITREVIKDIGYNSSDMGFDWASCSVLSAIGKQSLDIAQGVDNRETKI---LGAGDQG 121 Query: 467 IMFGYATDETPELMPL----SHVLATK--------------------------------- 535 +MFGYA+ ET MP SH L + Sbjct: 122 LMFGYASRETDVCMPAPIAYSHRLMARQAELRKNNKLPWLRPDGKCQLTLKYDQGKPVAI 181 Query: 536 -----------------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 L ++E +IKPV+P ++L T +++NP+GRFVIGGP GD G Sbjct: 182 DTIVFSTQHAPEISHKDLVEAVREEIIKPVLPEEWLSAATRYYINPTGRFVIGGPLGDCG 241 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KDP+KVDRSGAY AR AK+++A+G+A +C +Q+SY Sbjct: 242 LTGRKIIVDTYGGMARHGGGCFSGKDPSKVDRSGAYAARHVAKNLVAAGIAEKCEIQVSY 301 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 AIGV EP S+ VD++GTG + + I+ L+K +FD P I + DL R +TAAYG Sbjct: 302 AIGVAEPTSISVDTFGTGHLRNNVIIDLIKTHFDLTPQGIIDHHDLFSPIYR--QTAAYG 359 Query: 1025 HFGRDDADFTWEVVKPLKFDKASA 1096 H+GRD WE + DK +A Sbjct: 360 HYGRD--GLPWE-----RLDKVAA 376
>Q8P0G6:METK_STRP8 S-adenosylmethionine synthetase - Streptococcus pyogenes serotype M18| Length = 398 Score = 290 bits (743), Expect = 8e-78 Identities = 169/383 (44%), Positives = 220/383 (57%), Gaps = 61/383 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D ++ VA ET T V V GEI+T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTGSVHVFGEISTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE--- 445 A +D ++VRDT IG+ + G A+ V ++ +QS DIAQGV+ R + Sbjct: 62 AYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSGDIAQGVNEALESREGDTDD 121 Query: 446 ---VGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK----------------- 553 +GAGDQG+MFG+A +ETPELMPL SH L +L K Sbjct: 122 LSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLAELRKSGEISYLRPDAKSQVTV 181 Query: 554 ----------------------------------EHVIKPVIPAKYLDENTIFHLNPSGR 631 E VIK VIPA YLD++T F +NP+GR Sbjct: 182 EYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGR 241 Query: 632 FVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASG 811 FVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+++A+G Sbjct: 242 FVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAAG 301 Query: 812 LARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKG 991 LA + VQ++YAIGV +P+SV VD++GT +P+ + V++ FD RP I LDLK+ Sbjct: 302 LATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPAGIIQMLDLKR- 360 Query: 992 GNRFIKTAAYGHFGRDDADFTWE 1060 + +TAAYGH GR D D WE Sbjct: 361 -PIYKQTAAYGHMGRTDIDLPWE 382
>Q5XBJ6:METK_STRP6 S-adenosylmethionine synthetase - Streptococcus pyogenes serotype M6| Length = 398 Score = 290 bits (743), Expect = 8e-78 Identities = 169/383 (44%), Positives = 220/383 (57%), Gaps = 61/383 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D ++ VA ET T V V GEI+T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTGSVHVFGEISTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE--- 445 A +D ++VRDT IG+ + G A+ V ++ +QS DIAQGV+ R + Sbjct: 62 AYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSGDIAQGVNEALESREGDTDD 121 Query: 446 ---VGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK----------------- 553 +GAGDQG+MFG+A +ETPELMPL SH L +L K Sbjct: 122 LSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLAELRKSGEISYLRPDAKSQVTV 181 Query: 554 ----------------------------------EHVIKPVIPAKYLDENTIFHLNPSGR 631 E VIK VIPA YLD++T F +NP+GR Sbjct: 182 EYDEHDKPVRVDTVVISTQHDPEATNNQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGR 241 Query: 632 FVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASG 811 FVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+++A+G Sbjct: 242 FVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAAG 301 Query: 812 LARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKG 991 LA + VQ++YAIGV +P+SV VD++GT +P+ + V++ FD RP I LDLK+ Sbjct: 302 LATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPAGIIQMLDLKR- 360 Query: 992 GNRFIKTAAYGHFGRDDADFTWE 1060 + +TAAYGH GR D D WE Sbjct: 361 -PIYKQTAAYGHMGRTDIDLPWE 382
>Q8K715:METK_STRP3 S-adenosylmethionine synthetase - Streptococcus pyogenes serotype M3| Length = 398 Score = 290 bits (743), Expect = 8e-78 Identities = 169/383 (44%), Positives = 220/383 (57%), Gaps = 61/383 (15%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D ++ VA ET T V V GEI+T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTGSVHVFGEISTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE--- 445 A +D ++VRDT IG+ + G A+ V ++ +QS DIAQGV+ R + Sbjct: 62 AYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSGDIAQGVNEALESREGDTDD 121 Query: 446 ---VGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK----------------- 553 +GAGDQG+MFG+A +ETPELMPL SH L +L K Sbjct: 122 LSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLAELRKSGEISYLRPDAKSQVTV 181 Query: 554 ----------------------------------EHVIKPVIPAKYLDENTIFHLNPSGR 631 E VIK VIPA YLD++T F +NP+GR Sbjct: 182 EYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGR 241 Query: 632 FVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASG 811 FVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+++A+G Sbjct: 242 FVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAAG 301 Query: 812 LARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKG 991 LA + VQ++YAIGV +P+SV VD++GT +P+ + V++ FD RP I LDLK+ Sbjct: 302 LATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPAGIIQMLDLKR- 360 Query: 992 GNRFIKTAAYGHFGRDDADFTWE 1060 + +TAAYGH GR D D WE Sbjct: 361 -PIYKQTAAYGHMGRTDIDLPWE 382
>P43762:METK_HAEIN S-adenosylmethionine synthetase - Haemophilus influenzae| Length = 384 Score = 290 bits (743), Expect = 8e-78 Identities = 170/376 (45%), Positives = 219/376 (58%), Gaps = 54/376 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLD L QD ++VACET KT M +V GEITT A Sbjct: 3 SYLFTSESVSEGHPDKIADQISDAVLDEILKQDPKARVACETYVKTGMALVGGEITTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 VD E + R +IG+ ++G D C VL I +QS DI QGV + P + GAGD Sbjct: 63 VDIENLTRKVICDIGYEHSEMGFDGHSCAVLNAIGKQSADINQGVD---RENPLDQGAGD 119 Query: 461 QGIMFGYATDET----PELMPLSHVLATK------------------------------- 535 QGIMFGYAT+ET P + +H L K Sbjct: 120 QGIMFGYATNETDVLMPAAITYAHRLMEKQSEVRKSGKLAWLRPDAKSQVTLKYEDNKIV 179 Query: 536 -------------------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGD 658 L + E +IKPV+P+++L + T F +NP+GRFVIGGP GD Sbjct: 180 GVDAVVLSTQHSEEVSQKDLHEGVMEEIIKPVLPSEWLSKETKFFINPTGRFVIGGPMGD 239 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 GLTGRKII+DTY K+P+KVDRS AY AR AK+I+A+GLA RC +Q+ Sbjct: 240 CGLTGRKIIVDTYGGAARHGGGAFSGKEPSKVDRSAAYAARYVAKNIVAAGLADRCEIQL 299 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAA 1018 SYAIGV EP S+ V+++GTGK+ + ++ LV+E FD RP + LDL + R +TAA Sbjct: 300 SYAIGVAEPTSIMVETFGTGKVANELLVSLVREFFDLRPYGLIKMLDLIQPIYR--ETAA 357 Query: 1019 YGHFGRDDADFTWEVV 1066 YGHFGR+ F WE V Sbjct: 358 YGHFGRE--QFPWEKV 371
>Q4QLC5:METK_HAEI8 S-adenosylmethionine synthetase - Haemophilus influenzae (strain| 86-028NP) Length = 384 Score = 290 bits (743), Expect = 8e-78 Identities = 170/376 (45%), Positives = 218/376 (57%), Gaps = 54/376 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 ++LFTSESV+EGHPDK+ DQ+SDAVLD L QD ++VACET KT M +V GEITT A Sbjct: 3 SYLFTSESVSEGHPDKIADQISDAVLDEILKQDPKARVACETYVKTGMALVGGEITTSAW 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGD 460 VD E + R +IG+ ++G D C VL I +QS DI QGV + P + GAGD Sbjct: 63 VDIENLTRKVICDIGYEHSEMGFDGHSCAVLNAIGKQSADINQGVD---RENPLDQGAGD 119 Query: 461 QGIMFGYATDET----PELMPLSHVLATK------------------------------- 535 QGIMFGYAT+ET P + +H L K Sbjct: 120 QGIMFGYATNETDVLMPAAITYAHRLMEKQAEVRKSGKLAWLRPDAKSQVTLKYEDNKIV 179 Query: 536 -------------------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGD 658 L + E +IKPV+P ++L + T F +NP+GRFVIGGP GD Sbjct: 180 GVDAVVLSTQHSEEVSQKDLHEGVMEEIIKPVLPTEWLSKETKFFINPTGRFVIGGPMGD 239 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+ Sbjct: 240 CGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQL 299 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAA 1018 SYAIGV +P S+ V+++GTGK+ + ++ LV+E FD RP + LDL + R +TAA Sbjct: 300 SYAIGVADPTSIMVETFGTGKVANELLVSLVREFFDLRPYGLIKMLDLIQPIYR--ETAA 357 Query: 1019 YGHFGRDDADFTWEVV 1066 YGHFGR+ F WE V Sbjct: 358 YGHFGRE--QFPWEKV 371
>Q311V1:METK_DESDG S-adenosylmethionine synthetase - Desulfovibrio desulfuricans (strain| G20) Length = 391 Score = 290 bits (742), Expect = 1e-77 Identities = 166/373 (44%), Positives = 218/373 (58%), Gaps = 56/373 (15%) Frame = +2 Query: 110 FTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVDY 289 FTSESV EGHPDK+ DQ+SDAVLD L QD DS+VACET+ T M ++ GEITT+ D Sbjct: 10 FTSESVTEGHPDKVADQISDAVLDVLLEQDPDSRVACETMVTTGMAIIAGEITTRGYADL 69 Query: 290 EKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQGI 469 ++VRDT + IG+ + +G D C VL +I++QSPDIAQGV + PE GAGDQG+ Sbjct: 70 PQVVRDTIKEIGYNNSSMGFDWQTCAVLSSIDKQSPDIAQGVD---RQDPENQGAGDQGM 126 Query: 470 MFGYATDETPELMPL----SHVLATKLGA------------------------------- 544 MFG+A DETP LMP +H L+ KL A Sbjct: 127 MFGFACDETPTLMPAPIFWAHQLSQKLTAVRKDGTVDFLRPDGKTQVSFEYVDGRPVRIN 186 Query: 545 -------------------RLKEHVIKPVI-PAKYLDENTI-FHLNPSGRFVIGGPHGDA 661 ++ HVI+PV+ P+ + +E +N +GRFVIGGP GD Sbjct: 187 NVVVSTQHAEQASQTDIIDAIRTHVIRPVLEPSGFFNEKDCEIFINTTGRFVIGGPMGDC 246 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 GLTGRKII DTY KDP+KVDRSGAY+ R AK+++A+GLA +C VQI+ Sbjct: 247 GLTGRKIIQDTYGGMGSHGGGAFSGKDPSKVDRSGAYMGRYIAKNVVAAGLAPKCEVQIA 306 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 Y IGV +P+SV S G+ I D + + V++ FD RP IS LDL++ + K+A Y Sbjct: 307 YCIGVADPVSVLCTSLGSSDISDEVLTQAVRDVFDLRPYHISKRLDLRR--PIYKKSACY 364 Query: 1022 GHFGRDDADFTWE 1060 GHFGR+ +F+WE Sbjct: 365 GHFGREIPEFSWE 377
>Q493F2:METK_BLOPB S-adenosylmethionine synthetase - Blochmannia pennsylvanicus (strain| BPEN) Length = 389 Score = 290 bits (741), Expect = 1e-77 Identities = 169/383 (44%), Positives = 224/383 (58%), Gaps = 54/383 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 + FTSESV+EGHPDK+ DQ+SDA+LD+ LAQD ++VACET KT +V++ GEITT A V Sbjct: 4 YSFTSESVSEGHPDKIADQISDAILDSILAQDPRARVACETYVKTGIVIMGGEITTTAWV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 + E+I R+T R+IG++ D+G DA+ C +L I +QS DI + H + GAGDQ Sbjct: 64 NMEEIARNTIRDIGYVHSDMGFDANSCVILSVINKQSSDIQYSID-HGNTSTLQRGAGDQ 122 Query: 464 GIMFGYATDETPELM--PLSH--------------------------------------- 520 G+MFGYAT+ET M P+++ Sbjct: 123 GLMFGYATNETSVFMPAPITYAHRLIKRKSQVRKSGVLPWLGLDAKSQVTVAYEHGKIIG 182 Query: 521 -------------VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDA 661 + T L E +IKPV+P K+L NTIF +NP GRFVIGGP D Sbjct: 183 ITAVVLSIQHACDIKLTDLKEAAMEEIIKPVLPNKWLTNNTIFLINPGGRFVIGGPISDC 242 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 GLTGRKII+DTY KDP+KVDRS AY AR AK+I+A+GLA RC +Q+S Sbjct: 243 GLTGRKIIVDTYGGIGRHGGGSFSGKDPSKVDRSAAYGARYVAKNIVAAGLADRCELQVS 302 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIGVP P+S+ ++++GT KI +++L+K FDFRP + LDL + + +TA Y Sbjct: 303 YAIGVPHPISMSIETFGTEKISHDILMQLIKNFFDFRPYGLIAMLDLLR--PIYKETAVY 360 Query: 1022 GHFGRDDADFTWEVVKPLKFDKA 1090 GHFGR+ F WE K DKA Sbjct: 361 GHFGRE--CFPWE-----KIDKA 376
>P40320:METK_DROME S-adenosylmethionine synthetase - Drosophila melanogaster (Fruit fly)| Length = 408 Score = 288 bits (738), Expect = 3e-77 Identities = 165/384 (42%), Positives = 224/384 (58%), Gaps = 56/384 (14%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 TFLFTSESV EGHPDK+CDQ+SDA+LDA L QD ++KVACETV KT M+++ GEIT+KA Sbjct: 28 TFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAV 87 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVL-------------VNIEQQSPDIAQG--- 412 VDY+K+VR+T ++IG+ G D C VL V++ + +I G Sbjct: 88 VDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQQSPEIAAGVHVNRAEEEIGAGDQG 147 Query: 413 -VHGHFTKRPEE---------------VGAGDQGIMFGYATDETPE-------------- 502 + G+ T EE + + +F +A ++ Sbjct: 148 IMFGYATDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAV 207 Query: 503 -------LMPLSH---VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 ++ + H + L + + E V+K VIPAKY+D NTI H+NP G FVIGGP Sbjct: 208 PKRVHTIVVSMQHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPM 267 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GDAGLTGRKII+DTY KD TKVDRS AY AR AKS++ +GL +RC+V Sbjct: 268 GDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLV 327 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q+SYAIG+ EPLS+ V YGT +E+L +++ NFD RPG I +L+L++ + +T Sbjct: 328 QVSYAIGLAEPLSITVFDYGTSHKSQKELLDIIRRNFDLRPGKIVKDLNLRQ--PIYQRT 385 Query: 1013 AAYGHFGRDDADFTWEVVKPLKFD 1084 + YGHFGR A F+WE KPL+ D Sbjct: 386 STYGHFGR--AGFSWEEAKPLEID 407
>Q3Z943:METK_DEHE1 S-adenosylmethionine synthetase - Dehalococcoides ethenogenes (strain| 195) Length = 406 Score = 288 bits (738), Expect = 3e-77 Identities = 161/390 (41%), Positives = 223/390 (57%), Gaps = 60/390 (15%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV EGHPDK+CDQ+SDAVLDA +A+D ++ VACET +V+V+GEITT V Sbjct: 11 YLFTSESVTEGHPDKICDQISDAVLDAIIAKDPNAHVACETAVTNGLVVVMGEITTSCYV 70 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV----- 448 + ++VR ++IG+ + G D C VL +I +QSPDIA GV+ + +V Sbjct: 71 EIPELVRGVIKDIGYTKPEYGFDDRTCGVLTSINRQSPDIALGVNKSQEAKSGQVDELDL 130 Query: 449 -GAGDQGIMFGYATDETPELMP----LSHVLATKLG------------------------ 541 GAGDQG+MFGYA ETPE MP L+H L+ +L Sbjct: 131 TGAGDQGMMFGYACTETPEYMPLPISLAHRLSKRLSEVRKNGTLAYLRPDGKSQVTVEYH 190 Query: 542 --------------------------ARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 A + VIKP+IP LDENT +++N +GRFV+G Sbjct: 191 NGEAKRISSVVIGAQHDPDVTTEKIQADIIREVIKPIIPTNLLDENTEYYVNATGRFVVG 250 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GP D G TGRKI++DTY KDPTKVDRS Y+AR AK+++A+GLA R Sbjct: 251 GPVSDTGFTGRKILVDTYGGFARHGGGAFSGKDPTKVDRSACYMARYIAKNLVAAGLADR 310 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRF 1003 +Q++Y IGV PLSV ++++ T ++ +IL +++++FD RP I NL L++ R Sbjct: 311 LEIQVAYVIGVAHPLSVSIETFNTARMSHEDILSIIQKHFDLRPEAIIRNLGLRRPIYR- 369 Query: 1004 IKTAAYGHFGRDDADFTWEVVKPLKFDKAS 1093 +TAAYGH GR + D WE + + KA+ Sbjct: 370 -QTAAYGHLGRPELDLPWERLDKVDAIKAT 398
>Q98A80:METK_RHILO S-adenosylmethionine synthetase - Rhizobium loti (Mesorhizobium loti)| Length = 391 Score = 288 bits (737), Expect = 4e-77 Identities = 168/374 (44%), Positives = 221/374 (59%), Gaps = 55/374 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 F+F+SESV GHPDK+ D +SDA+LDA L D ++VACET+ KT MV++ GEIT+ A + Sbjct: 5 FVFSSESVGAGHPDKMADNISDAILDAILRTDPKARVACETLVKTGMVVLAGEITSHAVI 64 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 DY ++ RDT +IG+ D +G D RC V++ + +QSPDI+QGV + E+ GAGDQ Sbjct: 65 DYTQVARDTILDIGYDDDGIGFDGRRCAVVLALTEQSPDISQGVDEGRGQDLEQ-GAGDQ 123 Query: 464 GIMFGYATDETPELMPLSHVLA---TKLGARLK--------------------------- 553 G+MFG+A +ET LMPL LA TK A ++ Sbjct: 124 GLMFGFACNETDTLMPLPIQLAHHLTKRQAEVRKTGQLGWLRPDVKSQVSVRYEGLRPVA 183 Query: 554 ------------------------EHVIKPVIPAKYLDENTI-FHLNPSGRFVIGGPHGD 658 E +IKPV+P +LD I F +NP+GRFV+GGP GD Sbjct: 184 LDTIVLSTQHDEAVSQATVREGVIEEIIKPVLPT-HLDTTGIRFLVNPTGRFVVGGPAGD 242 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 GLTGRKII+D+Y KDP+KVDRS AY AR AK+I+ASGLA C VQ+ Sbjct: 243 CGLTGRKIIVDSYGGTGRHGGGAFSGKDPSKVDRSAAYAARYVAKNIVASGLAEVCEVQL 302 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAA 1018 +YAIGV P+SV V+++GT +I ++ I LV E FD RP I LDL + R TA Sbjct: 303 AYAIGVASPVSVMVNTFGTARIEEKRIECLVLELFDLRPKGIIKMLDLVRPIYR--NTAT 360 Query: 1019 YGHFGRDDADFTWE 1060 YGHFGR++ +FTWE Sbjct: 361 YGHFGREEPEFTWE 374
>Q3ZZN7:METK_DEHSC S-adenosylmethionine synthetase - Dehalococcoides sp. (strain CBDB1)| Length = 406 Score = 287 bits (734), Expect = 9e-77 Identities = 161/390 (41%), Positives = 222/390 (56%), Gaps = 60/390 (15%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV EGHPDK+CDQ+SDAVLDA +A+D + VACET +V+V+GEITT V Sbjct: 11 YLFTSESVTEGHPDKICDQISDAVLDAIIAKDPTAHVACETAVTNGLVVVMGEITTSCYV 70 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV----- 448 + ++VR ++IG+I + G D C VL +I +QSPDIA GV+ + +V Sbjct: 71 EIPELVRGVIKDIGYIKPEYGFDDRTCGVLTSINRQSPDIALGVNKSQEAKSGQVDELDL 130 Query: 449 -GAGDQGIMFGYATDETPELMP----LSHVLATKLG------------------------ 541 GAGDQG+MFGYA ETPE MP L+H L+ +L Sbjct: 131 TGAGDQGMMFGYACTETPEYMPLPISLAHRLSKRLAEVRKNGTLPYLRPDGKSQVTVEYH 190 Query: 542 --------------------------ARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIG 643 A + VIKP+IP LDE T +++N +GRFV+G Sbjct: 191 NGKAKRISSVVIGAQHDPDITTEKIQADIIREVIKPIIPTNLLDEKTEYYVNATGRFVVG 250 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GP D G TGRKI++DTY KDPTKVDRS Y+AR AK+++A+GLA R Sbjct: 251 GPVSDTGFTGRKILVDTYGGFARHGGGAFSGKDPTKVDRSACYMARYIAKNLVAAGLADR 310 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRF 1003 +Q++Y IGV PLSV ++++ T ++ +IL +++++FD RP I NL L++ R Sbjct: 311 LEIQVAYVIGVAHPLSVSIETFNTARMNHEDILSIIQKHFDLRPEAIIRNLGLRRPIYR- 369 Query: 1004 IKTAAYGHFGRDDADFTWEVVKPLKFDKAS 1093 +TAAYGH GR + D WE + + KA+ Sbjct: 370 -QTAAYGHLGRPELDLPWERLDKVDAIKAT 398
>Q2SS11:METK_MYCCT S-adenosylmethionine synthetase - Mycoplasma capricolum subsp.| capricolum (strain California kid / ATCC 27343 / NCTC 10154) Length = 387 Score = 285 bits (730), Expect = 3e-76 Identities = 162/375 (43%), Positives = 220/375 (58%), Gaps = 54/375 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E LFTSESV+EGHPDK+CDQ+SDA+LD L QD ++KVACE T TN +++ G+I++ A Sbjct: 6 EKRLFTSESVSEGHPDKICDQISDAILDEVLKQDKNAKVACEVFTTTNYLLIGGQISSTA 65 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 VDYE++ RD + IG++ D G++A+ CK+ + IE QSPDIAQGV +++GAG Sbjct: 66 IVDYEQVARDVLKKIGYVDDAYGINANTCKIDIKIESQSPDIAQGVE----LSNDQIGAG 121 Query: 458 DQGIMFGYATDETPELMPL----SHVLATKLGARLKEHVIKPVIP--------------- 580 DQGIMFGYAT+E+ +PL +H L ++ K+ + K P Sbjct: 122 DQGIMFGYATNESKTYLPLAITIAHELVYNATSQRKKGLFKWARPDMKSQVTIDYTNINN 181 Query: 581 ---------------------AKYLDENTI------FHL--------NPSGRFVIGGPHG 655 KY+ EN + F+L NP+GRFVIGGP G Sbjct: 182 PKIDTILMSIQHDPNYNEIEFKKYIKENIMDLVAKEFNLNTDFKVLINPTGRFVIGGPQG 241 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII DTY KD TKVDRS AY+ R AK+++A+GLA + +Q Sbjct: 242 DTGLTGRKIIADTYGGYSRHGGGAFSGKDSTKVDRSAAYMCRYVAKNLVAAGLADKIEIQ 301 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 +SYAIG+ +P+S+F++++ T K+ I K V ENFDF + LDLKK F KT+ Sbjct: 302 VSYAIGISQPISIFIETFNTHKVDLNTIYKAVYENFDFSVSSMIKTLDLKK--PIFFKTS 359 Query: 1016 AYGHFGRDDADFTWE 1060 YGHFG+ D +WE Sbjct: 360 KYGHFGK--KDLSWE 372
>Q2J843:METK2_FRASC S-adenosylmethionine synthetase 2 - Frankia sp. (strain CcI3)| Length = 398 Score = 283 bits (725), Expect = 1e-75 Identities = 170/384 (44%), Positives = 212/384 (55%), Gaps = 64/384 (16%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKAT 280 T LFTSESV EGHPDK+ DQ+SD++LDA + D S+VA ET+ T V V GE+TTK Sbjct: 3 TRLFTSESVTEGHPDKIADQISDSILDAMIKDDPKSRVAVETLITTGQVHVAGEVTTKTY 62 Query: 281 VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPE------ 442 VD +VR+ IG+ S G D C V V+I QSPDIAQGV R E Sbjct: 63 VDIASVVRERILEIGYDSSKKGFDGASCGVSVSIGAQSPDIAQGVDTAHETRVEGSADDE 122 Query: 443 --EVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLKEHVI-------KPVIPA 583 GAGDQG+MFG+A DETPELMPL +H LA +L A KE I K + Sbjct: 123 FDRQGAGDQGLMFGFACDETPELMPLPIALAHRLARRLSAVRKEGQIGYLRPDGKTQVTI 182 Query: 584 KYLD---------------------------------------------ENTIFHLNPSG 628 +Y+D E +NP+G Sbjct: 183 EYVDGKPARLDTVVVSSQHAADIDLDTLLAPDIAEYVVEPELALLEIATEGRRLLVNPTG 242 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RF IGGP GDAGLTGRKII+DTY KDP+KVDRS AY R AK+++A+ Sbjct: 243 RFEIGGPMGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAA 302 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLA RC VQ++YAIG +P+ +FV+++GTG +PD +I V FD RP I +LDL + Sbjct: 303 GLASRCEVQVAYAIGKAQPVGLFVETFGTGTVPDIQIQDAVTSVFDLRPAAIIRDLDLLR 362 Query: 989 GGNRFIKTAAYGHFGRDDADFTWE 1060 + +TAAYGHFGR + DFTWE Sbjct: 363 --PVYAQTAAYGHFGRPELDFTWE 384
>Q47R14:METK_THEFY S-adenosylmethionine synthetase - Thermobifida fusca (strain YX)| Length = 397 Score = 282 bits (721), Expect = 3e-75 Identities = 168/381 (44%), Positives = 215/381 (56%), Gaps = 63/381 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQ+SDA+LD+ L D S+VA ET+ T +V V GE+TT VD Sbjct: 5 LFTSESVTEGHPDKIADQISDAILDSMLRDDPHSRVAVETLITTGLVHVAGEVTTSTYVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV------ 448 I+R+ IG+ S G D C V V+I QSPDIAQGV + R EE+ Sbjct: 65 IPTIIREKILEIGYDSSAKGFDGASCGVSVSIGGQSPDIAQGVDNAYEAREEEIFDDLDR 124 Query: 449 -GAGDQGIMFGYATDETPELMPL----SHVLATKL------------------------- 538 GAGDQG+MFGYA +ETPELMPL +H L+ +L Sbjct: 125 QGAGDQGLMFGYANNETPELMPLPITLAHALSQRLAEVRRDGTIPYLRPDGKTQVTVEYD 184 Query: 539 GAR--------------------------LKEHVIKPVIPAKYLD-ENTIFHLNPSGRFV 637 G R +KEHV+ PV+ L+ +N +NP+GRF Sbjct: 185 GNRPVRLDTVVVSSQHAPDIDLRELLTPDIKEHVVDPVVARYNLEADNYRLLVNPTGRFE 244 Query: 638 IGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLA 817 IGGP GDAGLTGRKII+DTY KDP+KVDRS AY R AK+I+A+GLA Sbjct: 245 IGGPMGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPSKVDRSAAYATRWVAKNIVAAGLA 304 Query: 818 RRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN 997 R VQ++YAIG P+ VF++++GT K+ ++ K V E FD RP I +LDL + Sbjct: 305 DRVEVQVAYAIGKAHPVGVFLETFGTEKVAPEQLEKAVLEVFDLRPAAIIRDLDLLR--P 362 Query: 998 RFIKTAAYGHFGRDDADFTWE 1060 + +T+ YGHFGR+ DFTWE Sbjct: 363 IYSQTSVYGHFGRELPDFTWE 383
>Q9L0Y3:METK_STRCO S-adenosylmethionine synthetase - Streptomyces coelicolor| Length = 402 Score = 281 bits (720), Expect = 4e-75 Identities = 170/386 (44%), Positives = 212/386 (54%), Gaps = 68/386 (17%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQ+SD +LDA L +D S+VA ET+ T +V V GE+TTKA D Sbjct: 5 LFTSESVTEGHPDKIADQISDTILDALLREDPTSRVAVETLITTGLVHVAGEVTTKAYAD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPE-------E 445 +VR IG+ S G D C V V+I QSPDIAQGV + R E Sbjct: 65 IANLVRGKILEIGYDSSKKGFDGASCGVSVSIGAQSPDIAQGVDTAYENRVEGDEDELDR 124 Query: 446 VGAGDQGIMFGYATDETPELMP----LSHVLATK-------------------------- 535 GAGDQG+MFGYA+DETP LMP L+H L+ + Sbjct: 125 QGAGDQGLMFGYASDETPTLMPLPVFLAHRLSKRLSEVRKNGTIPYLRPDGKTQVTIEYD 184 Query: 536 -------------------------LGARLKEHVIKPVIPAKYLD------ENTIFHLNP 622 L +KE V++P + A D EN +NP Sbjct: 185 GDKAVRLDTVVVSSQHASDIDLESLLAPDIKEFVVEPELKALLEDGIKIDTENYRLLVNP 244 Query: 623 SGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSII 802 +GRF IGGP GDAGLTGRKIIIDTY KDP+KVDRS AY R AK+++ Sbjct: 245 TGRFEIGGPMGDAGLTGRKIIIDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVV 304 Query: 803 ASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDL 982 A+GLA RC VQ++YAIG EP+ +FV+++GT K+ +I K + E FD RP I LDL Sbjct: 305 AAGLAARCEVQVAYAIGKAEPVGLFVETFGTAKVDTEKIEKAIDEVFDLRPAAIIRALDL 364 Query: 983 KKGGNRFIKTAAYGHFGRDDADFTWE 1060 + + +TAAYGHFGR+ DFTWE Sbjct: 365 LR--PIYAQTAAYGHFGRELPDFTWE 388
>Q729A3:METK_DESVH S-adenosylmethionine synthetase - Desulfovibrio vulgaris (strain| Hildenborough / ATCC 29579 / NCIMB 8303) Length = 391 Score = 281 bits (718), Expect = 6e-75 Identities = 168/375 (44%), Positives = 214/375 (57%), Gaps = 56/375 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 + FTSESV EGHPDK+ DQ+SDAVLD LAQD +S+VACET+ T M ++ GEITT+ Sbjct: 8 YYFTSESVTEGHPDKVADQISDAVLDVLLAQDPNSRVACETLVTTGMAVIAGEITTRGYA 67 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 D +VR+T RNIG+ S ++G D C V+ +I++QS DIAQGV E+ GAGDQ Sbjct: 68 DLPHVVRETIRNIGYNSSEMGFDWQTCAVISSIDKQSADIAQGVD---RATNEDQGAGDQ 124 Query: 464 GIMFGYATDETPELMPLSHVLATKLGARLKE-------HVIKP----VIPAKYLD----- 595 G+MFG+A DET LMP A +L RL E + +P + +Y+D Sbjct: 125 GMMFGFACDETATLMPAPIYWAHQLSQRLTEVRKDGTVDIFRPDGKTQVSFEYVDGKPVR 184 Query: 596 -ENTIFH------------------------LNPSG---------------RFVIGGPHG 655 N + L PSG RFVIGGP G Sbjct: 185 INNVVVSTQHKDSASQADIIDAVKTHVIRPILEPSGFFDEKACDIFINTTGRFVIGGPMG 244 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII DTY KD +KVDRSGAY+AR AK+++ASGLA +C VQ Sbjct: 245 DCGLTGRKIIQDTYGGMGHHGGGAFSGKDASKVDRSGAYMARYIAKNVVASGLAPKCEVQ 304 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 I+Y IGV EP+SV V S GT +PD + + V+E FD RP I+ LDL + + KT+ Sbjct: 305 IAYCIGVAEPVSVLVSSQGTASVPDEVLTRAVREVFDLRPFHITRRLDLLR--PIYGKTS 362 Query: 1016 AYGHFGRDDADFTWE 1060 YGHFGR+ +FTWE Sbjct: 363 CYGHFGRELPEFTWE 377
>Q6MTB6:METK_MYCMS S-adenosylmethionine synthetase - Mycoplasma mycoides subsp. mycoides| SC Length = 387 Score = 278 bits (711), Expect = 4e-74 Identities = 159/375 (42%), Positives = 217/375 (57%), Gaps = 54/375 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 E LFTSESV+EGHPDK+CDQ+SDA+LD L QD ++KVACE TN +++ G+I++ A Sbjct: 6 EKRLFTSESVSEGHPDKICDQISDAILDEVLKQDKNAKVACEVFATTNYLLIGGQISSTA 65 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 V+YE++ RD + G++ D G++A+ CK+ + IE QSPDIAQGV +++GAG Sbjct: 66 IVNYEQVARDVLKKNGYVDDAYGINANTCKIDIKIESQSPDIAQGVE----LSNDQIGAG 121 Query: 458 DQGIMFGYATDETPELMPL----SHVLATKLGARLKEHVIKPVIP--------------- 580 DQGIMFGYAT+E+ +PL +H L ++ K+ + K P Sbjct: 122 DQGIMFGYATNESKTYLPLAITIAHELVYNATSQRKKGLFKWARPDMKSQVTIDYTNINN 181 Query: 581 ---------------------AKYLDENTI------FHL--------NPSGRFVIGGPHG 655 KY+ EN + F+L NP+GRFVIGGP G Sbjct: 182 PKIDTILMSIQHDPNYNETEFKKYIKENIMNLVAKEFNLNTDFKVLINPTGRFVIGGPQG 241 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 D GLTGRKII DTY KD TKVDRS AY+ R AK+++A+GLA + +Q Sbjct: 242 DTGLTGRKIIADTYGGYSRHGGGAFSGKDSTKVDRSAAYMCRYVAKNLVAAGLADKIEIQ 301 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 +SYAIG+ +P+S+F++++ T K+ I K V ENFDF + LDLKK F KT+ Sbjct: 302 VSYAIGISQPISIFIETFNTHKVDLNTIYKAVYENFDFSVSSMIKTLDLKK--PIFFKTS 359 Query: 1016 AYGHFGRDDADFTWE 1060 YGHFG+ D WE Sbjct: 360 KYGHFGK--KDLPWE 372
>Q7VFY5:METK_HELHP S-adenosylmethionine synthetase - Helicobacter hepaticus| Length = 386 Score = 278 bits (711), Expect = 4e-74 Identities = 162/387 (41%), Positives = 215/387 (55%), Gaps = 54/387 (13%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ++FLFTSESV EGHPDK+ DQ+SDAVLD + +D ++VACET+ ++ GE+ T Sbjct: 3 KSFLFTSESVTEGHPDKMADQISDAVLDYIIERDKKARVACETLVSNGFCVIAGELKTSV 62 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 ++I R + IG+ G D VL I +QSPDI QGV + E+GAG Sbjct: 63 YAPMQEIARKVVQEIGYTDALYGFDYRSAAVLNGIGEQSPDINQGVD----REDGEIGAG 118 Query: 458 DQGIMFGYATDETPELMPL----SHVLATKLGARLK------------------------ 553 DQG+MFGYA ETP LMPL SH L L + K Sbjct: 119 DQGLMFGYACKETPSLMPLPIWLSHRLTEGLAKKRKDGTLPFLRPDGKSQVTVRYEDGKP 178 Query: 554 --------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 E +++ V+P +YL++N + +NP+G+FVIGGP G Sbjct: 179 VSIDTIVISTQHSPETQQSHLKDAVIEEIVQKVLPQEYLNDNIRYFVNPTGKFVIGGPQG 238 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 DAGLTGRKII+DTY KDP+KVDRS AY AR AK+++ASG+ + IVQ Sbjct: 239 DAGLTGRKIIVDTYGGSCPHGGGAFSGKDPSKVDRSAAYAARYVAKNLVASGVCDKAIVQ 298 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 ++YAIGV EP+S+ VD+ GTGK+ D ++ + VK F P I +LDL + R KTA Sbjct: 299 VAYAIGVVEPVSILVDTQGTGKVEDSKLTECVKAVFRLTPKGIIESLDLLRPIYR--KTA 356 Query: 1016 AYGHFGRDDADFTWEVVKPLKFDKASA 1096 AYGHFGR+ +F+WE K DK A Sbjct: 357 AYGHFGRELNEFSWE-----KTDKVEA 378
>Q30PN0:METK_THIDN S-adenosylmethionine synthetase - Thiomicrospira denitrificans| (strain ATCC 33889 / DSM 1351) Length = 392 Score = 277 bits (709), Expect = 7e-74 Identities = 157/381 (41%), Positives = 210/381 (55%), Gaps = 54/381 (14%) Frame = +2 Query: 83 KEMAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGE 262 +E + ++FTSESV EGHPDK+ DQ+SDA+LD + D + VACET+ ++ GE Sbjct: 4 EEKTLKEYIFTSESVTEGHPDKMADQISDAILDYIIEHDPSAHVACETLVSNGFCVIAGE 63 Query: 263 ITTKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPE 442 + T A ++IVR + IG+ G D VL I +QSPDI QGV T Sbjct: 64 LKTTAYAPMQEIVRRVVQEIGYTDATYGFDYRSAAVLNGIGEQSPDITQGV----TLLDG 119 Query: 443 EVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLKE------------------ 556 E+GAGDQG+MFGYA ET LMPL +H+L +L KE Sbjct: 120 EIGAGDQGLMFGYACRETDVLMPLPIYLAHLLTRRLAEVRKEGIIPYLRPDGKAQISVKY 179 Query: 557 --------------------------------HVIKPVIPAKYLDENTIFHLNPSGRFVI 640 VI+ VIPA+ + E T+FH+NP+G+FVI Sbjct: 180 IGDKPVSVEAVVVSTQHAPEVSQEKIREDVIRDVIRAVIPAELMSEKTLFHINPTGKFVI 239 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GDAGLTGRKII+DTY KDPTKVDRS AY R AK+++A+G+ Sbjct: 240 GGPQGDAGLTGRKIIVDTYGGSCPHGGGAFSGKDPTKVDRSAAYACRHVAKNLVAAGVCD 299 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 R +QI+YAIG+ P+S+ +D++ T + +++I VKE FD P I +LDL + R Sbjct: 300 RVTIQIAYAIGISAPVSIMIDTHNTAIVEEKKIESCVKELFDLTPKGIIKSLDLLRPIYR 359 Query: 1001 FIKTAAYGHFGRDDADFTWEV 1063 KTA YGHFGR++ FTWE+ Sbjct: 360 --KTAVYGHFGREEEGFTWEL 378
>Q8E0A3:METK_STRA5 S-adenosylmethionine synthetase - Streptococcus agalactiae serotype V| Length = 398 Score = 277 bits (708), Expect = 9e-74 Identities = 169/386 (43%), Positives = 222/386 (57%), Gaps = 62/386 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA L QD D+ VA ET T V V GEI+T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILEQDPDAHVAAETAVYTGSVHVFGEISTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH------GHFTKR 436 A VD ++VR+T IG+ + G A+ V ++ +QSPDIAQGV+ G + Sbjct: 62 AYVDINRVVRNTIAEIGYDKAEYGFSAESVGVHPSLVEQSPDIAQGVNEALEVRGSLEQD 121 Query: 437 PEE-VGAGDQGIMFGYATDET----PELMPLSH--------------------------- 520 P + +GAGDQG+MFG+A DET P + L+H Sbjct: 122 PLDLIGAGDQGLMFGFAVDETPELMPLPISLAHQLVKKLTDLRKSGELTYLRPDAKSQVT 181 Query: 521 ---------------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSG 628 V++T+ L + E VI VIP+ YLD+ T F +NP+G Sbjct: 182 VEYDENDQPIRVDAVVISTQHDPNVTNDQLHKDVIEKVINEVIPSHYLDDQTKFFINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I+A+ Sbjct: 242 RFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 LA++ VQ++YAIGV +P+SV VD++GTG I + ++ V++ FD RP I LDLK+ Sbjct: 302 DLAKKVEVQLAYAIGVAQPVSVRVDTFGTGVIAEADLEAAVRQIFDLRPAGIINMLDLKR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVV 1066 R +TAAYGH GR D D WE V Sbjct: 362 PIYR--QTAAYGHMGRTDIDLPWERV 385
>Q8E5Y0:METK_STRA3 S-adenosylmethionine synthetase - Streptococcus agalactiae serotype| III Length = 398 Score = 277 bits (708), Expect = 9e-74 Identities = 169/386 (43%), Positives = 222/386 (57%), Gaps = 62/386 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA L QD D+ VA ET T V V GEI+T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILEQDPDAHVAAETAVYTGSVHVFGEISTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH------GHFTKR 436 A VD ++VR+T IG+ + G A+ V ++ +QSPDIAQGV+ G + Sbjct: 62 AYVDINRVVRNTIAEIGYDKAEYGFSAESVGVHPSLVEQSPDIAQGVNEALEVRGSLEQD 121 Query: 437 PEE-VGAGDQGIMFGYATDET----PELMPLSH--------------------------- 520 P + +GAGDQG+MFG+A DET P + L+H Sbjct: 122 PLDLIGAGDQGLMFGFAVDETPELMPLPISLAHQLVKKLTDLRKSGELTYLRPDAKSQVT 181 Query: 521 ---------------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSG 628 V++T+ L + E VI VIP+ YLD+ T F +NP+G Sbjct: 182 VEYDENNQPIRVDAVVISTQHDPNVTNDQLHKDVIEKVINEVIPSHYLDDQTKFFINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I+A+ Sbjct: 242 RFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 LA++ VQ++YAIGV +P+SV VD++GTG I + ++ V++ FD RP I LDLK+ Sbjct: 302 DLAKKVEVQLAYAIGVAQPVSVRVDTFGTGVIAEADLEAAVRQIFDLRPAGIINMLDLKR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVV 1066 R +TAAYGH GR D D WE V Sbjct: 362 PIYR--QTAAYGHMGRTDIDLPWERV 385
>Q3K1M7:METK_STRA1 S-adenosylmethionine synthetase - Streptococcus agalactiae serotype| Ia Length = 398 Score = 277 bits (708), Expect = 9e-74 Identities = 169/386 (43%), Positives = 222/386 (57%), Gaps = 62/386 (16%) Frame = +2 Query: 95 AETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK 274 +E LFTSESV+EGHPDK+ DQ+SDA+LDA L QD D+ VA ET T V V GEI+T Sbjct: 2 SERKLFTSESVSEGHPDKIADQISDAILDAILEQDPDAHVAAETAVYTGSVHVFGEISTT 61 Query: 275 ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH------GHFTKR 436 A VD ++VR+T IG+ + G A+ V ++ +QSPDIAQGV+ G + Sbjct: 62 AYVDINRVVRNTIAEIGYDKAEYGFSAESVGVHPSLVEQSPDIAQGVNEALEVRGSLEQD 121 Query: 437 PEE-VGAGDQGIMFGYATDET----PELMPLSH--------------------------- 520 P + +GAGDQG+MFG+A DET P + L+H Sbjct: 122 PLDLIGAGDQGLMFGFAVDETPELMPLPISLAHQLVKKLTDLRKSGELTYLRPDAKSQVT 181 Query: 521 ---------------VLATK---------LGARLKEHVIKPVIPAKYLDENTIFHLNPSG 628 V++T+ L + E VI VIP+ YLD+ T F +NP+G Sbjct: 182 VEYDENDQPIRVDAVVISTQHDPNVTNDQLHKDVIEKVINEVIPSHYLDDQTKFFINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFVIGGP GD+GLTGRKII+DTY KD TKVDRS +Y AR AK+I+A+ Sbjct: 242 RFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 LA++ VQ++YAIGV +P+SV VD++GTG I + ++ V++ FD RP I LDLK+ Sbjct: 302 DLAKKVEVQLAYAIGVAQPVSVRVDTFGTGVIAEADLEAAVRQIFDLRPAGIINMLDLKR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVV 1066 R +TAAYGH GR D D WE V Sbjct: 362 PIYR--QTAAYGHMGRTDIDLPWERV 385
>Q827Q0:METK_STRAW S-adenosylmethionine synthetase - Streptomyces avermitilis| Length = 402 Score = 276 bits (707), Expect = 1e-73 Identities = 168/386 (43%), Positives = 212/386 (54%), Gaps = 68/386 (17%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQ+SD +LDA L +D S+VA ET+ T +V V GE+TTKA Sbjct: 5 LFTSESVTEGHPDKIADQISDTILDALLREDPTSRVAVETLITTGLVHVAGEVTTKAYAP 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPE-------E 445 ++VRD IG+ S G D C V V+I QSPDIAQGV + R E Sbjct: 65 IAQLVRDKILEIGYDSSKKGFDGASCGVSVSIGSQSPDIAQGVDTAYENRVEGDEDELDR 124 Query: 446 VGAGDQGIMFGYATDETPELMP--------LSHVLA------------------------ 529 GAGDQG+MFGYATDETP LMP LSH L+ Sbjct: 125 QGAGDQGLMFGYATDETPTLMPLPIHLAHRLSHRLSEVRKNGTIPYLRPDGKTQVTIEYD 184 Query: 530 -----------------------TKLGARLKEHVIKPVIPA------KYLDENTIFHLNP 622 + L ++E V++P + A K E +NP Sbjct: 185 GDKAVRLDTVVVSSQHASDIDLDSLLAPDIREFVVEPELKALLDDGIKLETEGYRLLVNP 244 Query: 623 SGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSII 802 +GRF IGGP GDAGLTGRKIIIDTY KDP+KVDRS AY R AK+++ Sbjct: 245 TGRFEIGGPMGDAGLTGRKIIIDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVV 304 Query: 803 ASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDL 982 A+GLA RC VQ++YAIG EP+ +FV+++GT K+ +I + + FD RP I +LDL Sbjct: 305 AAGLASRCEVQVAYAIGKAEPVGLFVETFGTAKVEADKIEQAIATVFDLRPAAIIRDLDL 364 Query: 983 KKGGNRFIKTAAYGHFGRDDADFTWE 1060 + + +TAAYGHFGR+ DFTWE Sbjct: 365 LR--PIYSQTAAYGHFGRELPDFTWE 388
>O17680:METM_CAEEL Probable S-adenosylmethionine synthetase 1 - Caenorhabditis elegans| Length = 403 Score = 275 bits (703), Expect = 3e-73 Identities = 164/385 (42%), Positives = 214/385 (55%), Gaps = 56/385 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 FLFTSESV+EGHPDK+CDQ+SDAVLDA L QD ++KVACETVTKT MVM+ GEIT+KA V Sbjct: 5 FLFTSESVSEGHPDKMCDQISDAVLDAHLKQDPNAKVACETVTKTGMVMLCGEITSKAVV 64 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVL-------------VNIEQQSPDIAQG---- 412 DY+ +VR IGF +G D C VL V++ + D+ G Sbjct: 65 DYQVLVRRVIEKIGFTDSSIGFDHKTCNVLVALEQQSPEIAAGVHVNKDGEDVGAGDQGI 124 Query: 413 VHGHFTKRPEEV------------------------------GAGDQGIMFGYATDETPE 502 + G+ T EE I + T Sbjct: 125 MFGYATDETEETMPLTLILSHKINAELHKLRRNGTLPWVRPDSKSQVTIEYESRHGATIP 184 Query: 503 LMPLSHVLAT---------KLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 L + V++T KL + VIK VIPA LDE+T+FH+NP G F++GGP G Sbjct: 185 LRVHTVVVSTQHSPDVTLEKLRETILADVIKKVIPASLLDESTVFHINPCGTFIVGGPMG 244 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 DAG+TGRKII+DTY KDPTKVDRS AY AR A S++ +GLA+R +VQ Sbjct: 245 DAGVTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVATSLVKAGLAKRVLVQ 304 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 +SYAIG+ +P+SV V ++GT + D E+ ++V+++FD PG I LDLK+ + KTA Sbjct: 305 LSYAIGIAKPISVLVYAFGTSPLTDEELHQIVEDSFDLTPGKIIKELDLKR--PIYEKTA 362 Query: 1016 AYGHFGRDDADFTWEVVKPLKFDKA 1090 GHFG ++F WE K LK A Sbjct: 363 ENGHFGH--SEFPWEQPKALKISPA 385
>Q2RYY4:METK_SALRD S-adenosylmethionine synthetase - Salinibacter ruber (strain DSM| 13855) Length = 386 Score = 275 bits (702), Expect = 5e-73 Identities = 157/376 (41%), Positives = 216/376 (57%), Gaps = 57/376 (15%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQ+SDA+LDA LA+D +S+VA ET+ + +V++ GEIT++A V Sbjct: 3 YLFTSESVSEGHPDKIADQISDAILDAHLAEDRNSRVAAETLVTSGLVVLSGEITSQARV 62 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 + +I R+ R+IG+ + DA+ C V+ ++ +QS DI+QGV G EE GAGDQ Sbjct: 63 EPREIAREVIRDIGYTDPRIRFDAESCGVISSLHEQSGDISQGVDGG-----EEQGAGDQ 117 Query: 464 GIMFGYA----------------------------TDETPELMPLSHVLAT--------- 532 G+MFGYA TD+ P L P S T Sbjct: 118 GLMFGYACRETEELMPMPITFSHRLVQELAHIRKETDKMPYLRPDSKSQVTIEYKEDRMT 177 Query: 533 --------------------KLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPH 652 K+ +++ ++ +P LDE+ I H+NP+GRFV GGPH Sbjct: 178 PRRVHTVVVSTQHDEGVPQKKIREDVRDILLPRALPTDLLDEDLILHVNPTGRFVTGGPH 237 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GD G+TGRKII+DTY KDP+KVDRS Y AR AK+++A+ L V Sbjct: 238 GDTGVTGRKIIVDTYGGKGAHGGGAFSGKDPSKVDRSATYAARHVAKNLVAAELCDEAEV 297 Query: 833 QISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKT 1012 Q++YAIGV EP+S+ V + GTG +PD E+ ++V+E+F+ P I LDL K R+ KT Sbjct: 298 QLAYAIGVAEPVSIDVSTNGTGVLPDTELCEMVREHFELSPSAIIDRLDLLK--PRYQKT 355 Query: 1013 AAYGHFGRDDADFTWE 1060 AAYGHFGR F WE Sbjct: 356 AAYGHFGR--PTFPWE 369
>Q7VRG5:METK_BLOFL S-adenosylmethionine synthetase - Blochmannia floridanus| Length = 385 Score = 274 bits (700), Expect = 8e-73 Identities = 158/386 (40%), Positives = 219/386 (56%), Gaps = 55/386 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 FLFTSESV+ GHPDK+ DQ+SD++LD+ L QD ++VACET KT +V++ GEITT A+V Sbjct: 4 FLFTSESVSAGHPDKIADQISDSILDSILEQDPKARVACETYIKTGIVLIGGEITTTASV 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 + EKI R+T + IG+ +GLDA+ C +L I QQSP+I ++ H + R ++ GAGDQ Sbjct: 64 NIEKIARNTIQEIGYTHPKMGLDANSCVILSVINQQSPEIQYSIN-HDSDRTQQ-GAGDQ 121 Query: 464 GIMFGYATDETPELMP------------------------------------------LS 517 G MFGYAT+ET LMP + Sbjct: 122 GSMFGYATNETDVLMPAPITYAHRLIQRKSKLRKNGTLPWLGLDAKSQITFAYDENNKII 181 Query: 518 HVLATKLGAR-------------LKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGD 658 H+ A L + E +IKPV+P K+L + T F +N G F IG P D Sbjct: 182 HITAVVLSVQHNKNIPLEALREATMEEIIKPVLPQKWLSKQTKFFINSGGTFTIGSPISD 241 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 GLTGRKII+DTY KDP+KVDRS AY AR AAK+I+A+GLA RC +Q+ Sbjct: 242 CGLTGRKIIVDTYGGMARHGGGSFSGKDPSKVDRSAAYAARYAAKNIVAAGLAERCEIQL 301 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAA 1018 +YAIG+ P++V ++++GT K+ ++ L+ FDF P + L+L + + TA Sbjct: 302 AYAIGIANPIAVNIETFGTEKVLHSTLVTLINNFFDFSPHGVIKMLNLAR--PIYKDTAV 359 Query: 1019 YGHFGRDDADFTWEVVKPLKFDKASA 1096 YGHFGR+ F WE + + + SA Sbjct: 360 YGHFGRE--QFPWEKIDKVDLLRNSA 383
>Q9X4Q2:METK_STRST S-adenosylmethionine synthetase - Streptomyces spectabilis| Length = 411 Score = 273 bits (698), Expect = 1e-72 Identities = 166/386 (43%), Positives = 211/386 (54%), Gaps = 68/386 (17%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ DQ+SD +LDA L +D S+VA ET+ T +V V GE+TTKA Sbjct: 5 LFTSESVTEGHPDKIADQISDTILDALLREDPTSRVAVETLITTGLVHVAGEVTTKAYAP 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPE-------E 445 ++VR+ IG+ S G D C V V+I QSPDIAQGV + R E Sbjct: 65 IAQLVREKILEIGYDSSKKGFDGASCGVSVSIGAQSPDIAQGVDTAYESRVEGDEDELDR 124 Query: 446 VGAGDQGIMFGYATDETPELMP----LSHVLATK-------------------------- 535 GAGDQG+MFGYA DETPELMP L+H L+ + Sbjct: 125 QGAGDQGLMFGYACDETPELMPLPIHLAHRLSRRLSEVRKNGTIPYLRPDGKTQVTIEYD 184 Query: 536 -------------------------LGARLKEHVIKPVIPAKYLD------ENTIFHLNP 622 L ++E V++P + A D E +NP Sbjct: 185 GDKAVRLDTVVVSSQHASDIDLESLLAPDIREFVVEPELKALVEDGIKLETEGYRLLVNP 244 Query: 623 SGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSII 802 +GRF IGGP GDAGLTGRKIIIDTY KDP+KVDRS AY R AK+++ Sbjct: 245 TGRFEIGGPMGDAGLTGRKIIIDTYGGMSRHGGGAFSGKDPSKVDRSAAYAMRWVAKNVV 304 Query: 803 ASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDL 982 A+GLA RC VQ++YAIG EP+ +FV+++GT I +I + + E FD RP I +LDL Sbjct: 305 AAGLASRCEVQVAYAIGKAEPVGLFVETFGTNTIDTDKIEQAISEVFDLRPAAIIRDLDL 364 Query: 983 KKGGNRFIKTAAYGHFGRDDADFTWE 1060 + + +TAAYGHFGR +FTWE Sbjct: 365 LR--PIYSQTAAYGHFGRSLPEFTWE 388
>Q8G3H4:METK_BIFLO S-adenosylmethionine synthetase - Bifidobacterium longum| Length = 406 Score = 273 bits (697), Expect = 2e-72 Identities = 170/404 (42%), Positives = 224/404 (55%), Gaps = 69/404 (17%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M E L ++ESV EGHPDK+CDQ+SDA+LD LAQD+ S VA ET T + +V GE+T Sbjct: 1 MTEEHRLISAESVTEGHPDKVCDQISDAILDDLLAQDSSSHVAVETSAATGVFLVFGEVT 60 Query: 269 TKATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH---------G 421 ++ D + VR+T RNIG+ S +VGLDAD C V+V I +QS +I QGV Sbjct: 61 SEGYCDVQSKVRETLRNIGYTSSEVGLDADSCGVVVAITEQSAEINQGVARLTGDQETAA 120 Query: 422 HFTKRPEEVGAGDQGIMFGYATDET---------------------------PELMP--- 511 +R E GAGDQG+MFGYATDET P L P Sbjct: 121 SREERYEAQGAGDQGVMFGYATDETPTLMPLPIYLAHRLAFHLTEVRKSGEVPHLRPDGK 180 Query: 512 ---------------LSHVLATK----------LGARLKEHVIKPVIP----AKYLDENT 604 L VL + L LK+HVI PV+ +K +N Sbjct: 181 TQVTIEYDDDDKPVRLDTVLISTQHDPEVTQDWLAVELKKHVIDPVLDEVLGSKVPHDNY 240 Query: 605 IFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQ 784 +NP+G F++GGP DAGLTGRKII+DTY KDP+KVDRS AY R Sbjct: 241 RQLVNPTGSFILGGPAADAGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSAAYATRW 300 Query: 785 AAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGK-IPDREILKLVKENFDFRPGM 961 AK+I+A+GLA + +QI+YAIGV +P+SV V+++GT + + +I V++ FD RP Sbjct: 301 VAKNIVAAGLAHKVEIQIAYAIGVADPVSVNVETFGTEQGVTRGQIAAAVRKVFDLRPAA 360 Query: 962 ISINLDLKKGGNRFIKTAAYGHFGRDDADFTWEVVKPLKFDKAS 1093 I LDLK+ ++KTAAYGHFGR D +F WE ++ KA+ Sbjct: 361 IIDELDLKR--PIYLKTAAYGHFGRTDVEFPWEKTDKVEELKAA 402
>Q741G5:METK_MYCPA S-adenosylmethionine synthetase - Mycobacterium paratuberculosis| Length = 403 Score = 272 bits (695), Expect = 3e-72 Identities = 167/393 (42%), Positives = 213/393 (54%), Gaps = 69/393 (17%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ + LFTSESV EGHPDK+CD +SD+VLDA LAQD S+VA ET+ T V V+GE+T Sbjct: 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAQDPRSRVAVETLVTTGQVHVVGEVT 60 Query: 269 T---KATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP 439 T +A D VR+ +IG+ S D G D C V + I QSPDIAQGV R Sbjct: 61 TTAKEAFADITNTVRERILDIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHETRV 120 Query: 440 EEV-------GAGDQGIMFGYATDETPELMPLSHVLATKLGARLK--------------- 553 E GAGDQG+MFGYA +TPE+MPL LA +L RL Sbjct: 121 EGAADPLDAQGAGDQGLMFGYAIKDTPEMMPLPIALAHRLSRRLTEVRKSGVLPYLRPDG 180 Query: 554 -------------------------------EHVIKPVIPAKYLD-------------EN 601 E+ + P I K L+ + Sbjct: 181 KTQVTIEYEDDVPVRLDTVVVSTQHAADIDLENTLTPDIREKVLNTVLDDLAHDTLDTSS 240 Query: 602 TIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIAR 781 T +NP+G+FV+GGP GDAGLTGRKII+DTY KDP+KVDRS AY R Sbjct: 241 TRLLVNPTGKFVVGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query: 782 QAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGM 961 AK+I+A+GLA R VQ++YAIG P+ +FV+++GT + +I K+V E FD RPG Sbjct: 301 WVAKNIVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTATVDPVKIEKIVPEVFDLRPGA 360 Query: 962 ISINLDLKKGGNRFIKTAAYGHFGRDDADFTWE 1060 I +LDL + + +TAAYGHFGR D + WE Sbjct: 361 IIRDLDLLR--PIYAQTAAYGHFGRTDVELPWE 391
>Q938W7:METK_STRFR S-adenosylmethionine synthetase - Streptomyces fradiae| Length = 407 Score = 270 bits (690), Expect = 1e-71 Identities = 163/391 (41%), Positives = 213/391 (54%), Gaps = 73/391 (18%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+ D++SD VLDA LA+D ++VA ET+ T V + GE+TT A Sbjct: 5 LFTSESVTEGHPDKIADRISDTVLDALLARDPRARVAVETLITTGQVHIAGEVTTTAYAP 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP--------- 439 ++VRDT +IG+ S G D C V V+I QSPDIA+GV + +R Sbjct: 65 IAQLVRDTVLSIGYDSSAKGFDGASCGVSVSIGAQSPDIARGVDTAYERRGGGTAPGGPG 124 Query: 440 ---EEVGAGDQGIMFGYATDETPELMP----LSHVLATK--------------------- 535 + GAGDQG+MFGYA DETPELMP L+H L+ + Sbjct: 125 DELDRQGAGDQGLMFGYACDETPELMPLPINLAHRLSRRLSEVRKNGTIPYLRPDGKTQV 184 Query: 536 ------------------------------LGARLKEHVIKPVIPAKYLDENTI------ 607 L ++ HV++PV+ D + Sbjct: 185 TIEYDGDKAVRLDTVVVSSQHASGIDLDSLLAPDIRRHVVEPVLAGLAEDGIKLDTAGYR 244 Query: 608 FHLNPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQA 787 +NP+GRF IGGP GDAGLTGRKIIIDTY KDP+KVDRS AY R Sbjct: 245 LLVNPTGRFEIGGPMGDAGLTGRKIIIDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWV 304 Query: 788 AKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMIS 967 AK+++A+GLA RC VQ++YAIG EP+ +FV+++GT + I + + E FD RP I Sbjct: 305 AKNVVAAGLASRCEVQVAYAIGKAEPVGLFVETFGTATVDVERIEQAIGEVFDLRPAAII 364 Query: 968 INLDLKKGGNRFIKTAAYGHFGRDDADFTWE 1060 +LDL + + KTAAYGHFGR+ +FTWE Sbjct: 365 RDLDLLR--PIYAKTAAYGHFGRELPEFTWE 393
>Q9ZMN5:METK_HELPJ S-adenosylmethionine synthetase - Helicobacter pylori J99| (Campylobacter pylori J99) Length = 385 Score = 269 bits (687), Expect = 3e-71 Identities = 157/385 (40%), Positives = 210/385 (54%), Gaps = 54/385 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ++FLFTSESV EGHPDK+ DQ+SDAVLD + +D +KVACET+ M+ GE+ T Sbjct: 3 DSFLFTSESVTEGHPDKMADQISDAVLDYIIERDKKAKVACETLVSNGFCMITGELKTSV 62 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 ++I R+ + IG+ G D VL I +QSPDI QGV + E+GAG Sbjct: 63 YAPMQEIAREVVKKIGYTDALYGFDYRSAAVLNGIGEQSPDINQGVD----REDGEIGAG 118 Query: 458 DQGIMFGYATDETPELMPL----SHVLATKLGARLK------------------------ 553 DQG+MFGYA ET LMPL +H LA L + K Sbjct: 119 DQGLMFGYACKETETLMPLPIHLAHQLAFALAQKRKDNTLPFLRPDGKSQVSVRYENNKP 178 Query: 554 --------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 E ++ V+P +YL +N F +NP+G+FVIGGP G Sbjct: 179 VSVDTIVISTQHSPEVSQKHLKEAVIEEIVYKVLPKEYLHDNIKFFINPTGKFVIGGPQG 238 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 DAGLTGRKII+DTY KDP+KVDRS AY AR AK+++ASG+ + VQ Sbjct: 239 DAGLTGRKIIVDTYGGFCPHGGGAFSGKDPSKVDRSAAYAARYVAKNLVASGVCDKATVQ 298 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 ++YAIGV EP+S++V+++ T K E+ K VK F P I +LDL + + T+ Sbjct: 299 LAYAIGVIEPVSIYVNTHNTSKHSSAELEKCVKSVFKLTPKGIIESLDLLR--PIYSLTS 356 Query: 1016 AYGHFGRDDADFTWEVVKPLKFDKA 1090 AYGHFGR+ +FTWE ++ KA Sbjct: 357 AYGHFGRELEEFTWEKTNKVEEIKA 381
>Q4JVH7:METK_CORJK S-adenosylmethionine synthetase - Corynebacterium jeikeium (strain| K411) Length = 411 Score = 268 bits (686), Expect = 3e-71 Identities = 163/390 (41%), Positives = 214/390 (54%), Gaps = 72/390 (18%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LF+SESV EGHPDK+CD +SD +LDA +A+D +++VA ETV T +V V+GEI T V+ Sbjct: 5 LFSSESVTEGHPDKICDAISDKILDALIAKDPEARVAVETVVTTGLVHVVGEIRTTTYVE 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE------- 445 +VR T IGF S D+G D C V V I +QS +IAQGV R + Sbjct: 65 IPALVRKTLLEIGFNSSDMGFDGSTCGVSVAIGEQSQEIAQGVDTALEHRSHDAEGGAEL 124 Query: 446 -----VGAGDQGIMFGYATDETPELMPL----SHVLATKL-------------------- 538 +GAGDQG+MFGYAT+ETPE MPL +H L+ +L Sbjct: 125 DEIDRLGAGDQGLMFGYATNETPEYMPLPIALAHRLSRRLTEVRKKGIVPHLRPDGKTQV 184 Query: 539 -------GA------------------------RLKEHVIKPVIPAKYL-----DENTIF 610 GA +++ HV++ V+ L D + Sbjct: 185 TFAYDAEGAPVRLDTVVVSTQHDAGIEQEWLHEQIRTHVVQHVLDEAGLSGNLADTDYTL 244 Query: 611 HLNPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAA 790 +NPSG FV+GGP GDAGLTGRKII+DTY KDP+KVDRSGAY R A Sbjct: 245 LVNPSGSFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSGAYAMRWVA 304 Query: 791 KSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISI 970 K+I+A+GLA R VQ++YAIG P+ ++V+++GT K P I V++ FD RP I Sbjct: 305 KNIVAAGLADRAEVQVAYAIGRATPVGLYVETFGTEKAPVEAIQAAVRQVFDLRPAAILQ 364 Query: 971 NLDLKKGGNRFIKTAAYGHFGRDDADFTWE 1060 LDLK+ + +T+AYGHFGR D D WE Sbjct: 365 ELDLKR--PIYAQTSAYGHFGRTDLDLPWE 392
>P61945:METK_CORDI S-adenosylmethionine synthetase - Corynebacterium diphtheriae| Length = 410 Score = 267 bits (682), Expect = 1e-70 Identities = 164/387 (42%), Positives = 210/387 (54%), Gaps = 69/387 (17%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+CD +SD +LDA L+ D ++VA ETVT T +V V+GE+ T V+ Sbjct: 11 LFTSESVTEGHPDKICDAISDTILDALLSVDPHARVAVETVTTTGLVHVVGEVRTSGYVE 70 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH-------GHFTKRPEE 445 K+VRD IGF S +VG D C V V+I +QS +I GV G T ++ Sbjct: 71 IPKLVRDKLIEIGFNSSEVGFDGRTCGVSVSIGEQSQEIGAGVDQSHEVRSGENTDADDQ 130 Query: 446 VGAGDQGIMFGYATDETPELMPL----SHVLATKLG------------------------ 541 GAGDQG+MFGYAT+ET LMPL +H LA +L Sbjct: 131 AGAGDQGLMFGYATNETATLMPLPIDLAHRLARRLTQVRKTSVVSHLRPDGKTQVTLAYD 190 Query: 542 ---------------------------ARLKEHVIKPVIPAKYLDENTIFH-----LNPS 625 A++KEHV+ V+ L+ +NPS Sbjct: 191 ESGRPVRLDTVVVSTQHDPDVTQEWLFAQIKEHVVDWVLRDSGLESTLDISGYSLLVNPS 250 Query: 626 GRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIA 805 G FV+GGP GDAGLTGRKII+DTY KDP+KVDRSGAY R AK+I+A Sbjct: 251 GSFVVGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSGAYAMRWVAKNIVA 310 Query: 806 SGLARRCIVQISYAIGVPEPLSVFVDSYGTGK--IPDREILKLVKENFDFRPGMISINLD 979 +GLA R VQ++YAIG +P+ ++V+++GT K + D +I V FD RP I LD Sbjct: 311 AGLADRAEVQVAYAIGRAKPVGLYVETFGTAKFGLTDEQIQDAVLHVFDLRPAAIIRELD 370 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWE 1060 L + + TAAYGHFGRDD WE Sbjct: 371 LLR--PIYAGTAAYGHFGRDDLKLPWE 395
>Q7M7Z2:METK_WOLSU S-adenosylmethionine synthetase - Wolinella succinogenes| Length = 386 Score = 266 bits (681), Expect = 1e-70 Identities = 154/383 (40%), Positives = 211/383 (55%), Gaps = 54/383 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 FLFTSESV EGHPDK+ DQ+SDA+LD + +D ++VACET+ ++ GE+ T Sbjct: 5 FLFTSESVTEGHPDKMADQISDAILDYIIERDPKARVACETLLSNGFCVIAGELKTTTYA 64 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 ++I R+ R IG+ G D +L + +QSPDI QGV + E+GAGDQ Sbjct: 65 PMQEIAREVIREIGYTDALYGFDYRSAGILNGVGEQSPDINQGVD----REDGEIGAGDQ 120 Query: 464 GIMFGYATDETPELMPL----SHVLATKLGARLK-------------------------- 553 G+MFGYA ET LMPL SH + L K Sbjct: 121 GLMFGYACRETETLMPLPIFLSHKITEGLAKARKDGTLPFLRPDGKSQVTVRYVDGKPVG 180 Query: 554 ------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDA 661 E ++ V+P +YL ++ F +NP+G+FVIGGP GDA Sbjct: 181 IDTIVVSTQHAPDVSQERLRDAVIEEIVYKVLPKEYLGDDIRFFVNPTGKFVIGGPQGDA 240 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 GLTGRKII+D+Y KDP+KVDRSGAY AR AK+++ASG+ + +QI+ Sbjct: 241 GLTGRKIIVDSYGGSCPHGGGAFSGKDPSKVDRSGAYAARYVAKNLVASGVCDKATIQIA 300 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIGV EP+S+ VD++GTGK+ D ++ V++ F P I +LDL + + KTA+Y Sbjct: 301 YAIGVVEPVSILVDTHGTGKVEDDQLETCVRQLFRLTPKGIIESLDLLR--PIYKKTASY 358 Query: 1022 GHFGRDDADFTWEVVKPLKFDKA 1090 GHFGR+ +F+WE K DKA Sbjct: 359 GHFGRELPEFSWE-----KTDKA 376
>Q5YTN0:METK_NOCFA S-adenosylmethionine synthetase - Nocardia farcinica| Length = 404 Score = 266 bits (681), Expect = 1e-70 Identities = 161/385 (41%), Positives = 209/385 (54%), Gaps = 67/385 (17%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+CD +SD++LDA LA+D S+VA ET+ T V V GE+TT A D Sbjct: 8 LFTSESVTEGHPDKICDAISDSILDALLAEDPRSRVAVETLVTTGQVHVAGEVTTSAYAD 67 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKR----PEEV-- 448 +IVR+ IG+ S G D + C V + I QSPDIAQGV R +E+ Sbjct: 68 IPRIVREKVLEIGYDSSAKGFDGNSCGVNIAIGAQSPDIAQGVDTSHEARVGGTDDEIAK 127 Query: 449 -GAGDQGIMFGYATDETPELMPL----SHVLATK-------------------------- 535 GAGDQG+MFGYAT +TPELMPL +H L+ K Sbjct: 128 QGAGDQGLMFGYATTDTPELMPLPIALAHRLSRKLTEVRKTGVLPYLRPDGKTQVTIEYD 187 Query: 536 -------------------------LGARLKEHVIKPVI-----PAKYLDENTIFHLNPS 625 L ++E V+ V+ P+ + +NP+ Sbjct: 188 GDRPVRLDTVVISTQHAADIDLDNLLAPDIREKVVDAVLADLDLPSPLDTSDIRLLVNPT 247 Query: 626 GRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIA 805 G+FV+GGP GDAGLTGRKII+DTY KDP+KVDRS AY R AK+++A Sbjct: 248 GKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVA 307 Query: 806 SGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLK 985 +GL+ R VQ++YAIG P+ +FV+++GT K+ I + E FD RPG I +LDL Sbjct: 308 AGLSERVEVQVAYAIGKAAPVGLFVETFGTEKVDPARIAAAITEVFDLRPGAIIRDLDLL 367 Query: 986 KGGNRFIKTAAYGHFGRDDADFTWE 1060 + + TAAYGHFGR D D WE Sbjct: 368 R--PIYAPTAAYGHFGRTDIDLPWE 390
>Q9RWM6:METK_DEIRA S-adenosylmethionine synthetase - Deinococcus radiodurans| Length = 408 Score = 265 bits (677), Expect = 4e-70 Identities = 168/389 (43%), Positives = 217/389 (55%), Gaps = 72/389 (18%) Frame = +2 Query: 110 FTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITT-KATVD 286 +TSESV+EGHPDKL D +SD++LD L Q+ S+VA ET+ T M +V GE+ A VD Sbjct: 10 YTSESVSEGHPDKLSDFISDSILDEFLRQEPTSRVAVETLVTTGMAVVAGEVRAHTAHVD 69 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGV-HGHFTKRPEE------ 445 +K VR+ + +G+ + G DA+ VLV I +QSP+IA GV H + E Sbjct: 70 IQKTVREAVQRVGYTRANYGFDAEYSAVLVAIHEQSPEIASGVDHSEEWREMSEAERQKP 129 Query: 446 ------VGAGDQGIMFGYATDETPELMPLSHVLATKLGARLKE-------HVIKP----- 571 VGAGDQG+MFGYATDETPELMPL LA L RL E ++P Sbjct: 130 ENAYSMVGAGDQGLMFGYATDETPELMPLPISLAHGLTRRLAELRKDGTLPYLRPDAKAQ 189 Query: 572 --------------------VIPAKYLDENT--------IFHLNP--------------- 622 VI ++ D+ T + H+ P Sbjct: 190 VTVVRNGEPHSATETAVDTIVISTQHSDDVTQEQIRADMLEHVIPAVIPAELLNEQTRYF 249 Query: 623 ---SGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAK 793 SGRFVIGGPHGD GLTGRKII+DTY KDPTKVDRS AY AR AK Sbjct: 250 INPSGRFVIGGPHGDTGLTGRKIIVDTYGGAVPHGGGAFSGKDPTKVDRSAAYYARYVAK 309 Query: 794 SIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISIN 973 +I+A+GLARR +V+I+YAIG P+S+ VD+YGTG + D ++ +L+ +FD RP I Sbjct: 310 NIVAAGLARRALVEIAYAIGRAHPVSLRVDTYGTGTVSDEKLDELIAAHFDARPQAIIAQ 369 Query: 974 LDLKKGGNRFIKTAAYGHFGRDDADFTWE 1060 LDL++ + +TAAYGHFGR +F WE Sbjct: 370 LDLQR--PIYAQTAAYGHFGR--PEFPWE 394
>Q8FT48:METK_COREF S-adenosylmethionine synthetase - Corynebacterium efficiens| Length = 407 Score = 264 bits (675), Expect = 6e-70 Identities = 165/388 (42%), Positives = 212/388 (54%), Gaps = 70/388 (18%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+CD +SD +LDA L D S+VA ETV T +V V+GE+ T V+ Sbjct: 9 LFTSESVTEGHPDKICDAISDTILDALLTADPLSRVAVETVVTTGIVHVVGEVRTSGYVE 68 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVH--------GHFTKRPE 442 ++VR IGF S DVG D C V V+I +QS +IA GV GHF + + Sbjct: 69 IPQLVRRKLIEIGFTSSDVGFDGRTCGVSVSIGEQSQEIADGVDTSQEARGDGHF-EEDD 127 Query: 443 EVGAGDQGIMFGYATDETPELMPL----SHVLATKLG----------------------- 541 GAGDQG+MFGYAT+ETPE MPL +H LA +L Sbjct: 128 RAGAGDQGLMFGYATNETPEFMPLPIAVAHRLARRLTQVRKEGIVPHLRPDGKTQVTFAY 187 Query: 542 ----------------------------ARLKEHVIKPVIPAKYLD-----ENTIFHLNP 622 +L+EHVI VI L+ E T+ +NP Sbjct: 188 DADDNPSHLDTVVISTQHDPEVDSAWLEVQLREHVIDWVIRDAGLEHLATGEITVL-INP 246 Query: 623 SGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSII 802 SG F++GGP GDAGLTGRKII+DTY KDP+KVDRS AY R AK+I+ Sbjct: 247 SGSFILGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKNIV 306 Query: 803 ASGLARRCIVQISYAIGVPEPLSVFVDSYGTGK--IPDREILKLVKENFDFRPGMISINL 976 A+GLA R VQ++YAIG +P+ ++V+++ T + + D +I V + FD RP I L Sbjct: 307 AAGLADRAEVQVAYAIGRAKPVGLYVETFDTAREGLTDEQIQAAVSQVFDLRPAAIIREL 366 Query: 977 DLKKGGNRFIKTAAYGHFGRDDADFTWE 1060 DL + + +TAAYGHFGR D D WE Sbjct: 367 DLLR--PIYAQTAAYGHFGRTDLDLPWE 392
>P56460:METK_HELPY S-adenosylmethionine synthetase - Helicobacter pylori (Campylobacter| pylori) Length = 385 Score = 263 bits (673), Expect = 1e-69 Identities = 152/375 (40%), Positives = 204/375 (54%), Gaps = 54/375 (14%) Frame = +2 Query: 98 ETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKA 277 ++FLFTSESV EGHPDK+ DQ+SDAVLD + +D +KVACET+ M+ GE+ T Sbjct: 3 DSFLFTSESVTEGHPDKMADQISDAVLDYIIERDQKAKVACETLVSNGFCMITGELKTSV 62 Query: 278 TVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 ++I R+ + IG+ G D VL + +QSPDI QGV + E+GAG Sbjct: 63 YAPMQEIAREVVKKIGYTDALYGFDYRSAAVLNGVGEQSPDINQGVD----REDGEIGAG 118 Query: 458 DQGIMFGYATDETPELMPL----SHVLATKLGARLK------------------------ 553 DQG+MFGYA ET LMPL +H L L + K Sbjct: 119 DQGLMFGYACKETETLMPLPIHLAHQLTFALAQKRKDNTLPFLRPDGKSQVSVRYENNKP 178 Query: 554 --------------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHG 655 E ++ V+ +YL +N F +NP+G+FVIGGP G Sbjct: 179 VSIDTIVISTQHSPEVSQKHLKEAVIEEIVYKVLSKEYLHDNIKFFVNPTGKFVIGGPQG 238 Query: 656 DAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQ 835 DAGLTGRKII+DTY KDP+KVDRS AY AR AK+++ASG+ + VQ Sbjct: 239 DAGLTGRKIIVDTYGGSCPHGGGAFSGKDPSKVDRSAAYAARYVAKNLVASGVCDKATVQ 298 Query: 836 ISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTA 1015 ++YAIGV EP+S++V+++ T K E+ K VK F P I +LDL + + T+ Sbjct: 299 LAYAIGVIEPVSIYVNTHNTSKYSSAELEKCVKSVFKLTPKGIIESLDLLR--PIYSLTS 356 Query: 1016 AYGHFGRDDADFTWE 1060 AYGHFGR+ +FTWE Sbjct: 357 AYGHFGRELEEFTWE 371
>Q8RGE5:METK_FUSNN S-adenosylmethionine synthetase - Fusobacterium nucleatum subsp.| nucleatum Length = 383 Score = 263 bits (673), Expect = 1e-69 Identities = 159/373 (42%), Positives = 207/373 (55%), Gaps = 56/373 (15%) Frame = +2 Query: 110 FTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVDY 289 FTSE V+ GHPDK+ DQ+SDA+LDACL D +S+VACE T +V+V GEITT +D Sbjct: 7 FTSEFVSPGHPDKISDQISDAILDACLKDDPNSRVACEVFCTTGLVVVGGEITTSTYIDV 66 Query: 290 EKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQGI 469 + IVR IG+ +G D++ C L I QSPDIA GV + GAGDQGI Sbjct: 67 QDIVRKKIDEIGY-RPGMGFDSN-CGTLSCIHAQSPDIAMGV--------DIGGAGDQGI 116 Query: 470 MFGYATDETPELMPL----SHVLATKLGARLK---------------------------- 553 MFG A ET ELMPL S + KL +K Sbjct: 117 MFGGAVRETEELMPLALVLSREILVKLTNMMKSNEIEWARPDQKSQVTLAYDENGKVDHV 176 Query: 554 -----------------------EHVIKPVIPAKYLDENTI-FHLNPSGRFVIGGPHGDA 661 E V+KPV+ L + I +++NP+GRFVIGGPHGD Sbjct: 177 DSIVVSVQHDEDTTHDEIEKIVIEKVVKPVLEKYNLSSDNIKYYINPTGRFVIGGPHGDT 236 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 G+TGRKII+DTY KDP+KVDRS AY AR AK+I+A+ LA +C +Q+S Sbjct: 237 GVTGRKIIVDTYGGYFKHGGGAFSGKDPSKVDRSAAYAARWVAKNIVAAELADKCEIQLS 296 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIGVP+P+SV VD++GT K+ + +I + V + FD P I L+L++G ++ AA+ Sbjct: 297 YAIGVPKPVSVKVDTFGTSKVDEDKISEAVSKVFDLSPRGIEKALELREGNFKYQDLAAF 356 Query: 1022 GHFGRDDADFTWE 1060 GH GR D D WE Sbjct: 357 GHIGRTDIDTPWE 369
>Q5LLL2:METK_SILPO S-adenosylmethionine synthetase - Silicibacter pomeroyi| Length = 393 Score = 261 bits (668), Expect = 4e-69 Identities = 156/388 (40%), Positives = 214/388 (55%), Gaps = 64/388 (16%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ + ++FTSESV+EGHPDK+CD++SDAVLDA L ++ +++VACET TN V++ GE+ Sbjct: 1 MSRQNYIFTSESVSEGHPDKVCDRISDAVLDAFLTEEPEARVACETFATTNRVVIGGEVG 60 Query: 269 TKATVDY-------EKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHF 427 ++I RD ++IG+ D + ++ + +QS IAQGV+ Sbjct: 61 LSDQAKLREYMGRIDQIARDCIKDIGYEQDK--FHHETVEITNLLHEQSAHIAQGVNAAE 118 Query: 428 TKRPEEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK-------------- 553 K + GAGDQGIMFGYAT ETP LMP SH + +L K Sbjct: 119 GK---DEGAGDQGIMFGYATTETPALMPAPIQYSHAILRRLAEVRKNGTEPALGPDAKSQ 175 Query: 554 ------------------------------------EHVIKPVIPAKYLDENTIFHLNPS 625 E I+ V+P +L +T++H+NP+ Sbjct: 176 LSVIYRDGMPVGVSSLVLSTQHLDPDLTSADIRAIVEPYIREVLPEGWLSADTVWHVNPT 235 Query: 626 GRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIA 805 G+FVIGGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+++A Sbjct: 236 GKFVIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNVVA 295 Query: 806 SGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLK 985 +GLA +C +Q+SYAIGV +PLS++ D++GTG I I K + D P I +L L Sbjct: 296 AGLADKCTIQLSYAIGVSKPLSIYADTHGTGDIAPAAIEKAIDTVMDLTPRGIRTHLGLN 355 Query: 986 KGGNRFIKTAAYGHFGRD---DADFTWE 1060 K + +TAAYGHFGR+ D F+WE Sbjct: 356 K--PIYERTAAYGHFGREPEADGGFSWE 381
>Q9K5E4:METK_CORGL S-adenosylmethionine synthetase - Corynebacterium glutamicum| (Brevibacterium flavum) Length = 407 Score = 261 bits (666), Expect = 7e-69 Identities = 164/389 (42%), Positives = 213/389 (54%), Gaps = 69/389 (17%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+CD +SD +LDA L +D S+VA ETV T +V V+GE+ T A V+ Sbjct: 9 LFTSESVTEGHPDKICDAISDTILDALLEKDPQSRVAVETVVTTGIVHVVGEVRTSAYVE 68 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP-------EE 445 ++VR+ IGF S +VG D C V V+I +QS +IA GV R + Sbjct: 69 IPQLVRNKLIEIGFNSSEVGFDGRTCGVSVSIGEQSQEIADGVDNSDEARTNGDVEEDDR 128 Query: 446 VGAGDQGIMFGYATDETPELMPL------------------------------------- 514 GAGDQG+MFGYAT+ET E MPL Sbjct: 129 AGAGDQGLMFGYATNETEEYMPLPIALAHRLSRRLTQVRKEGIVPHLRPDGKTQVTFAYD 188 Query: 515 -----SH----VLATK---------LGARLKEHVIKPVIPAKYLD-----ENTIFHLNPS 625 SH V++T+ L +L+EHVI VI ++ E T+ +NPS Sbjct: 189 AQDRPSHLDTVVISTQHDPEVDRAWLETQLREHVIDWVIKDAGIEDLATGEITVL-INPS 247 Query: 626 GRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIA 805 G F++GGP GDAGLTGRKII+DTY KDP+KVDRS AY R AK+I+A Sbjct: 248 GSFILGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKNIVA 307 Query: 806 SGLARRCIVQISYAIGVPEPLSVFVDSYGTGK--IPDREILKLVKENFDFRPGMISINLD 979 +GLA R VQ++YAIG +P+ ++V+++ T K + D +I V E FD RP I LD Sbjct: 308 AGLADRAEVQVAYAIGRAKPVGLYVETFDTNKEGLSDEQIQAAVLEVFDLRPAAIIRELD 367 Query: 980 LKKGGNRFIKTAAYGHFGRDDADFTWEVV 1066 L + + TAAYGHFGR D D WE + Sbjct: 368 LLR--PIYADTAAYGHFGRTDLDLPWEAI 394
>Q2IZR2:METK_RHOP2 S-adenosylmethionine synthetase - Rhodopseudomonas palustris (strain| HaA2) Length = 398 Score = 259 bits (663), Expect = 2e-68 Identities = 150/387 (38%), Positives = 213/387 (55%), Gaps = 67/387 (17%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADS-------KVACETVTKTNMVMVLG 259 ++LFTSESV+EGHPDK+CD++SD V+D + + + ACET+ TN V++ G Sbjct: 4 SYLFTSESVSEGHPDKVCDRISDEVVDLFFREGPKAGIDPWAIRAACETLATTNKVVIAG 63 Query: 260 EITTKATV---DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFT 430 E A+V E +VR ++IG+ + G D C + + + QS DIAQGV Sbjct: 64 ETRGPASVTNDQIESVVRAAIKDIGY--EQEGFHWDTCDIEILLHPQSADIAQGVDALQP 121 Query: 431 KRPEEVGAGDQGIMFGYATDETPELMPL-------------------------------- 514 +E GAGDQGIMFGYAT+ETP+LMP Sbjct: 122 GTNKEEGAGDQGIMFGYATNETPDLMPAPIFYAHKILRLISEARHSGKEKVLGPDSKSQV 181 Query: 515 -------------------SHVLATKLGARLKEHV---IKPVIPAKYLDENTIFHLNPSG 628 H++ +++E V ++ +P ++ + TI+H+NP+G Sbjct: 182 TIQYENGKPVGVREIVVSHQHLVEDMTSNQVRERVEPYVRQALPDGWITDKTIWHINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 +F IGGP GD GLTGRKII+DTY KDPTKVDRS AY +R AK+I+A+ Sbjct: 242 KFYIGGPDGDTGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYASRYLAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLA RC +Q++YAIGV PLS+++D++GTGK+ + ++ K V E D P I +LDL K Sbjct: 302 GLADRCTLQLAYAIGVARPLSIYIDTHGTGKVSEDKLEKAVAEAMDLTPRGIRSHLDLNK 361 Query: 989 GGNRFIKTAAYGHFGRD---DADFTWE 1060 + +T++YGHFGR D F+WE Sbjct: 362 --PIYARTSSYGHFGRTPDADGGFSWE 386
>Q2RMS5:METK2_RHORT S-adenosylmethionine synthetase 2 - Rhodospirillum rubrum (strain| ATCC 11170 / NCIB 8255) Length = 389 Score = 259 bits (661), Expect = 3e-68 Identities = 154/383 (40%), Positives = 220/383 (57%), Gaps = 59/383 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MA +LFTSESV+EGHPDK+CD++SDA++DA LA+D S+VA ET+ TN V++ GE+ Sbjct: 1 MAQSEYLFTSESVSEGHPDKVCDRISDAIVDAFLAEDPHSRVALETMATTNFVVLAGEVR 60 Query: 269 TKATVDYEK---IVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP 439 ++ +++ I R+ ++IG+ + G +++ ++ QS DIA GV K Sbjct: 61 GPDSLTHDRLKEIAREAIKDIGY--EQRGFHWKDAEIVSHVHSQSADIAVGVDAAGNK-- 116 Query: 440 EEVGAGDQGIMFGYATDETPELMP----LSHVLATKL----------------------- 538 + GAGDQGIMFGYA ET ELMP LSH + L Sbjct: 117 -DEGAGDQGIMFGYACTETEELMPAPIALSHAILKSLAEFRHGGDTSFGPDSKSQVTLRY 175 Query: 539 ------GAR--------------------LKEHVIKPVIPAKYLDENTIFHLNPSGRFVI 640 GA ++ HV+K V+P ++ F++NP+GRFVI Sbjct: 176 VDGKPVGAASVVVSTQHAGNLSQDEVRELVRPHVLK-VLPEGWMCPEEEFYVNPTGRFVI 234 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GD GLTGRKII+DTY KDPTKVDRS AY AR AK+++A+GLA Sbjct: 235 GGPDGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNVVAAGLAE 294 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C++Q+SYAIGV +PLSV+V++ GTG++ ++ + ++++ D P I +L L + Sbjct: 295 KCVIQVSYAIGVSKPLSVYVNTQGTGQVDEQRLAVVLQQLMDLSPRGIRQHLQLSR--PI 352 Query: 1001 FIKTAAYGHFGR---DDADFTWE 1060 + +TAAYGHFGR D F+WE Sbjct: 353 YARTAAYGHFGRKPEKDGGFSWE 375
>Q2RVX7:METK1_RHORT S-adenosylmethionine synthetase 1 - Rhodospirillum rubrum (strain| ATCC 11170 / NCIB 8255) Length = 383 Score = 259 bits (661), Expect = 3e-68 Identities = 151/373 (40%), Positives = 206/373 (55%), Gaps = 54/373 (14%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 + TSESV EGHPDK+CDQ+SD +LDACLAQD ++VA ET+ N V + GEITT A + Sbjct: 4 YCVTSESVTEGHPDKVCDQISDGILDACLAQDPAARVAVETLVSGNTVFIAGEITTTARL 63 Query: 284 DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQ 463 D + R+ +IG+ +G D+ C +L N+ QSPDI GV R E+GAGDQ Sbjct: 64 DAVRTAREVIEDIGYADPALGFDSGSCFILTNLRTQSPDIDLGV-----SRGAELGAGDQ 118 Query: 464 GIMFGYATDETPELMP----LSHVLATKLGARL--------------------------- 550 G+++GYA DET LMP ++H L+ +L A Sbjct: 119 GVLYGYACDETASLMPAPIHMAHGLSLRLAAARHGGVLPWLRPDGKTQVTVRYDGEGRPE 178 Query: 551 ----------------KEHVIKPVIPA-------KYLDENTIFHLNPSGRFVIGGPHGDA 661 +E +++ +I A +L T +NP+GRFVIGGP GD Sbjct: 179 ALTSVIVSTQHDEGVDRETLVRGIIEAVIYPEVGGWLKPETRVLINPTGRFVIGGPAGDT 238 Query: 662 GLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQIS 841 G+TGRK+++DTY KD TKVDR+ AY+AR AAK+++A+GLARRC V ++ Sbjct: 239 GVTGRKLMVDTYGGCARHGGGAFSGKDSTKVDRTAAYMARYAAKNVVAAGLARRCEVALA 298 Query: 842 YAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAY 1021 YAIG P V V+++GT I + V+E F F + LDL++ F KTAAY Sbjct: 299 YAIGERLPEMVSVETFGTETIDVDRLTAAVRETFPFSVSGMIAALDLRR--PIFRKTAAY 356 Query: 1022 GHFGRDDADFTWE 1060 GHFGR++ F WE Sbjct: 357 GHFGRENKGFQWE 369
>Q9CCQ4:METK_MYCLE S-adenosylmethionine synthetase - Mycobacterium leprae| Length = 403 Score = 258 bits (660), Expect = 3e-68 Identities = 163/393 (41%), Positives = 211/393 (53%), Gaps = 69/393 (17%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ + LFTSESV EGHPDK+CD +SD++LDA LA+D S+VA ET+ T V V+GE+T Sbjct: 1 MSEKGRLFTSESVTEGHPDKICDAISDSILDALLAEDPCSRVAVETLVTTGQVHVVGEVT 60 Query: 269 TKATV---DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP 439 T A D VR+ +IG+ S D G D C V + I QS DIAQGV+ R Sbjct: 61 TLAKTAFADISNTVRERILDIGYDSSDKGFDGASCGVNIGIGAQSSDIAQGVNTAHEVRV 120 Query: 440 EEV-------GAGDQGIMFGYATDETPELMPL----SHVLATKLGARLKEHVI------- 565 E GAGDQG+MFGYA ++TPELMPL +H LA +L K V+ Sbjct: 121 EGAADPLDAQGAGDQGLMFGYAINDTPELMPLPIALAHRLARRLTEVRKNGVLPYLRSDG 180 Query: 566 KPVIPAKYLDE---------------------------------NTIFH----------- 613 K + Y D NT+ Sbjct: 181 KTQVTIAYEDNVPVRLDTVVISTQHAAGVDLDATLAPDIREKVLNTVIDDLSHDTLDVSS 240 Query: 614 ----LNPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIAR 781 +NP+G+FV+GGP GDAGLTGRKII+DTY KDP+KVDRS AY R Sbjct: 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query: 782 QAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGM 961 AK+I+A+GLA R VQ++YAIG P+ +FV+++GT + +I K + E FD RPG Sbjct: 301 WVAKNIVAAGLAERIEVQVAYAIGKAAPVGLFVETFGTEAVDPAKIEKAIGEVFDLRPGA 360 Query: 962 ISINLDLKKGGNRFIKTAAYGHFGRDDADFTWE 1060 I +L L + + +TAAYGHFGR D + WE Sbjct: 361 IIRDLHLLR--PIYAQTAAYGHFGRTDVELPWE 391
>Q2VYQ2:METK_MAGMM S-adenosylmethionine synthetase - Magnetospirillum magneticum (strain| AMB-1 / ATCC 700264) Length = 388 Score = 258 bits (659), Expect = 4e-68 Identities = 156/383 (40%), Positives = 217/383 (56%), Gaps = 59/383 (15%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ + FLFTSESV+EGHPDK+ D++SDAV+DA L D ++VA ET+ TN++++ GE+ Sbjct: 1 MSKKNFLFTSESVSEGHPDKVADRISDAVVDAFLGADPYARVAVETLVTTNLIVMAGEVR 60 Query: 269 TKATVD---YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP 439 A+V+ +++ R ++IG+ D G +++ + QS DIAQGV K Sbjct: 61 GPASVNAALMDELARHAVKDIGYEQD--GFHWKNAEIINRVHSQSADIAQGVDAAGDK-- 116 Query: 440 EEVGAGDQGIMFGYATDETPELMPL----SHVLATKLG---------------------- 541 + GAGDQGIMFGYA +ETP LMP SH + L Sbjct: 117 -DEGAGDQGIMFGYACNETPVLMPAPIYYSHEILKSLAEARHSGAAPQLLPDSKSQVTLE 175 Query: 542 ------------------------ARLKEHV---IKPVIPAKYLDENTIFHLNPSGRFVI 640 A +KE V +K V+P ++ F++NP+GRFVI Sbjct: 176 YRDGKPVRATSVVVSHQHVDGLSQADIKEIVRPHVKNVLPEGWMPAEDQFYVNPTGRFVI 235 Query: 641 GGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLAR 820 GGP GD GLTGRKII+DTY KDPTKVDRS AY AR AK+++ASGLA Sbjct: 236 GGPDGDTGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNVVASGLAD 295 Query: 821 RCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNR 1000 +C++Q+SYAIGV +PLSV+VD+ GT K+ + ++ ++++ D P I +L L K Sbjct: 296 KCVIQLSYAIGVSKPLSVYVDTSGTCKVDEDKLAVVLQQLVDLSPRGIRTHLGLNK--PI 353 Query: 1001 FIKTAAYGHFGRD---DADFTWE 1060 + +TAAYGHFGR D F+WE Sbjct: 354 YARTAAYGHFGRSPDADGGFSWE 376
>Q89HP5:METK_BRAJA S-adenosylmethionine synthetase - Bradyrhizobium japonicum| Length = 398 Score = 257 bits (657), Expect = 8e-68 Identities = 150/387 (38%), Positives = 212/387 (54%), Gaps = 67/387 (17%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADS-------KVACETVTKTNMVMVLG 259 ++LFTSESV+EGHPDK+CD++SD ++D + + + ACET+ TN V++ G Sbjct: 4 SYLFTSESVSEGHPDKVCDRISDEIVDLFYREGPKAGIDPWQIRAACETLATTNKVVIAG 63 Query: 260 EITTKATVDYEKI---VRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFT 430 E +V E+I VR ++IG+ + G C + + + QS DIAQGV Sbjct: 64 ETRGPKSVTNEQIEGVVRAAIKDIGY--EQEGFHWKTCDIEILLHPQSADIAQGVDALQP 121 Query: 431 KRPEEVGAGDQGIMFGYATDETPELMPLSHVLATK------------------------- 535 +E GAGDQGIMFGYAT+ETP+LMP A K Sbjct: 122 GEVKEEGAGDQGIMFGYATNETPDLMPAPIFYAHKILRLISEARHSGREKVLGPDSKSQV 181 Query: 536 ---------LGAR--------------------LKEHVIKPVIPAKYLDENTIFHLNPSG 628 +G R + E ++ +P ++ TI+H+NP+G Sbjct: 182 TVQYENGKPVGVREIVVSHQHLVPDLTSSQVRDIVEPYVREALPKDWITPKTIWHINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 +F IGGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+I+A+ Sbjct: 242 KFYIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLA RC +Q++YAIGV PLS+++D++GTGK+P+ ++ K + D P I +LDL + Sbjct: 302 GLADRCTLQLAYAIGVARPLSIYIDTHGTGKVPEEQLEKAAAQAMDLTPRGIRSHLDLNR 361 Query: 989 GGNRFIKTAAYGHFGR---DDADFTWE 1060 + +T+AYGHFGR ++ F+WE Sbjct: 362 --PIYARTSAYGHFGRTPDNEGGFSWE 386
>Q20YV7:METK2_RHOPB S-adenosylmethionine synthetase 2 - Rhodopseudomonas palustris| (strain BisB18) Length = 398 Score = 254 bits (648), Expect = 8e-67 Identities = 148/387 (38%), Positives = 212/387 (54%), Gaps = 67/387 (17%) Frame = +2 Query: 101 TFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADS-------KVACETVTKTNMVMVLG 259 ++LFTSESV+EGHPDK+CD++SD ++D + + + ACET+ TN V++ G Sbjct: 4 SYLFTSESVSEGHPDKVCDRISDEIVDLFFREGPKAGIDPWAIRAACETLATTNKVVIAG 63 Query: 260 EITTKATVDYEKI---VRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFT 430 E A+V E I VR+ ++IG+ D G + + + QS DIAQGV Sbjct: 64 ETRGPASVTNEHIEHVVREAIKDIGYEQD--GFHWKTADIEILLHPQSADIAQGVDALQP 121 Query: 431 KRPEEVGAGDQGIMFGYATDETPELMPL-------------------------------- 514 +E GAGDQGIMFGYAT+ETP+LMP Sbjct: 122 GTNQEEGAGDQGIMFGYATNETPDLMPAPIFYAHKILRLISEARHSGKEKVLGPDSKSQV 181 Query: 515 -------------------SHVLATKLGARLKEHV---IKPVIPAKYLDENTIFHLNPSG 628 H++ +++E V ++ +P ++ + TI+H+NP+G Sbjct: 182 TIQYENGKPVGVREIVVSHQHLVEDMTSNQVRERVEPYVREALPEGWITDKTIWHINPTG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 +F IGGP GD GLTGRKII+DTY KDPTKVDRS AY +R AK+I+A+ Sbjct: 242 KFFIGGPDGDTGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYASRYLAKNIVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLA RC +Q++YAIGV PLS+++D++GTGK+ + ++ K V E D P I +LDL K Sbjct: 302 GLADRCTLQLAYAIGVARPLSIYIDTHGTGKVTEDKLEKAVAEAMDLTPRGIRKHLDLNK 361 Query: 989 GGNRFIKTAAYGHFGRD---DADFTWE 1060 + +T++YGHFGR + F+WE Sbjct: 362 --PIYARTSSYGHFGRTPDAEGGFSWE 386
>P77899:METK_MYCTU S-adenosylmethionine synthetase - Mycobacterium tuberculosis| Length = 403 Score = 253 bits (647), Expect = 1e-66 Identities = 163/393 (41%), Positives = 209/393 (53%), Gaps = 69/393 (17%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ + LFTSESV EGHPDK+CD +SD+VLDA LA D S+VA ET+ T V V+GE+T Sbjct: 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVT 60 Query: 269 TKAT---VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP 439 T A D VR IG+ S D G D C V + I QSPDIAQGV R Sbjct: 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query: 440 EEV-------GAGDQGIMFGYATDETPELMP----LSHVLATK----------------- 535 E GAGDQG+MFGYA + TPELMP L+H L+ + Sbjct: 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query: 536 ----------------------------------LGARLKEHVIKPVIPA---KYLDENT 604 L ++E V+ V+ + LD +T Sbjct: 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 Query: 605 IFHL-NPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIAR 781 + L NP+G+FV+GGP GDAGLTGRKII+DTY KDP+KVDRS AY R Sbjct: 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query: 782 QAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGM 961 AK+++A+GLA R VQ++YAIG P+ +FV+++GT +I K + E FD RPG Sbjct: 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 Query: 962 ISINLDLKKGGNRFIKTAAYGHFGRDDADFTWE 1060 I +L+L + + TAAYGHFGR D + WE Sbjct: 361 IIRDLNLLR--PIYAPTAAYGHFGRTDVELPWE 391
>Q7U051:METK_MYCBO S-adenosylmethionine synthetase - Mycobacterium bovis| Length = 403 Score = 251 bits (642), Expect = 4e-66 Identities = 162/393 (41%), Positives = 208/393 (52%), Gaps = 69/393 (17%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ + LFTSESV EGHPDK+CD +SD+VLDA LA D S+VA ET+ T V V+GE+ Sbjct: 1 MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVA 60 Query: 269 TKAT---VDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRP 439 T A D VR IG+ S D G D C V + I QSPDIAQGV R Sbjct: 61 TSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARV 120 Query: 440 EEV-------GAGDQGIMFGYATDETPELMP----LSHVLATK----------------- 535 E GAGDQG+MFGYA + TPELMP L+H L+ + Sbjct: 121 EGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDG 180 Query: 536 ----------------------------------LGARLKEHVIKPVIPA---KYLDENT 604 L ++E V+ V+ + LD +T Sbjct: 181 KTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDAST 240 Query: 605 IFHL-NPSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIAR 781 + L NP+G+FV+GGP GDAGLTGRKII+DTY KDP+KVDRS AY R Sbjct: 241 VRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMR 300 Query: 782 QAAKSIIASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGM 961 AK+++A+GLA R VQ++YAIG P+ +FV+++GT +I K + E FD RPG Sbjct: 301 WVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGA 360 Query: 962 ISINLDLKKGGNRFIKTAAYGHFGRDDADFTWE 1060 I +L+L + + TAAYGHFGR D + WE Sbjct: 361 IIRDLNLLR--PIYAPTAAYGHFGRTDVELPWE 391
>Q2GBP1:METK_NOVAD S-adenosylmethionine synthetase - Novosphingobium aromaticivorans| (strain DSM 12444) Length = 401 Score = 250 bits (638), Expect = 1e-65 Identities = 163/392 (41%), Positives = 214/392 (54%), Gaps = 73/392 (18%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTK--- 274 +LFTSESV+EGHPDK+ DQ+SDA++D L++D ++++ACET+T T +V++ GEI K Sbjct: 5 YLFTSESVSEGHPDKVSDQISDAIVDLFLSKDPEARIACETLTTTQLVVLAGEIRCKGVY 64 Query: 275 --------ATVDYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFT 430 A + EK VRDT + IG+ D G +R + + + QS IAQGV Sbjct: 65 ENGEWAPGAQDEIEKTVRDTVKRIGYEQD--GFHWERLEFINRLHGQSAHIAQGVDAADN 122 Query: 431 KRPEEVGAGDQGIMFGYATDETPELMPL----SHVLATKLG------------------- 541 K + GAGDQGIMFGYATDETP+LMP SH + ++ Sbjct: 123 K---DEGAGDQGIMFGYATDETPDLMPATLYYSHKILERMAADRHSGAAPFLEPDAKSQV 179 Query: 542 -------------------------------ARLKEHV---IKPVIPAKYLDENTIFHLN 619 A L E+V + VIP L E T +++N Sbjct: 180 TLRYEGSLPVAATAVVVSTQHAPGYDEGGKEAELHEYVKRVVAEVIPPVLLRE-TKYYIN 238 Query: 620 PSGRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSI 799 P+G F IGGP GDAGLTGRKII+DTY KDPTKVDRS AYI R AK++ Sbjct: 239 PTGSFEIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYITRYLAKNV 298 Query: 800 IASGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKL---VKENFDFRPGMISI 970 +A+GLA RC +QI+YAIGV EPLS++VD++ TG + D +I + + + P I Sbjct: 299 VAAGLATRCTIQIAYAIGVSEPLSLYVDTHETGTVGDDKIEQAILGIAKLGGLTPRAIRT 358 Query: 971 NLDLKKGGNRFIKTAAYGHFGR--DDADFTWE 1060 +L L K R TAAYGHFGR D F WE Sbjct: 359 HLGLNKPIYR--PTAAYGHFGRKADGDFFPWE 388
>Q21A46:METK1_RHOPB S-adenosylmethionine synthetase 1 - Rhodopseudomonas palustris| (strain BisB18) Length = 383 Score = 250 bits (638), Expect = 1e-65 Identities = 146/370 (39%), Positives = 201/370 (54%), Gaps = 54/370 (14%) Frame = +2 Query: 113 TSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVDYE 292 TSESV EGHPDK+CDQ+SD +LDAC+AQD S+VA ET+ N+ ++ GEITT A +D E Sbjct: 7 TSESVTEGHPDKVCDQISDGILDACVAQDPASRVAVETLVSGNIAVIAGEITTTAQIDAE 66 Query: 293 KIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQGIM 472 + R + IG+ +G D+D C +L N+ QSPDI GV R +E+GAGDQG+ Sbjct: 67 RTARAVIKAIGYDDPALGFDSDSCFILTNLRTQSPDINLGV-----SRGDELGAGDQGVF 121 Query: 473 FGYATDETPELMPLSHVLATKLGARLK--------------------------------E 556 +GYA DET LMP+ LA L RL + Sbjct: 122 YGYACDETANLMPIPIALAHTLSLRLTMMRRDGTLPWLRPDGKVQVTMRYGRDGRPCGLD 181 Query: 557 HVIKPVIPAKYLDENTIFH--------------LNPSGR--------FVIGGPHGDAGLT 670 V+ + +D +T+ L P R FV+GGP GD G+T Sbjct: 182 SVVVSAQHDEAVDRDTLVRGLVEGVIYPELHDWLQPGTRVLINPTGRFVVGGPAGDTGVT 241 Query: 671 GRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAI 850 GRK+++DTY KD TKVDR+ AY+AR AAK+++A+GLA RC + ++YAI Sbjct: 242 GRKLMVDTYGGCAQHGGGAFSGKDATKVDRTAAYMARYAAKNVVAAGLAGRCQLALAYAI 301 Query: 851 GVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYGHF 1030 G +P + V+++GT + I V+E F + + L+L++ RF KTAAYGHF Sbjct: 302 GQIDPEMISVETFGTETVDGDRICAAVREVFPWTVSGMIAALELRQ--PRFRKTAAYGHF 359 Query: 1031 GRDDADFTWE 1060 GR+D F WE Sbjct: 360 GREDQGFQWE 369
>Q28UI9:METK_JANSC S-adenosylmethionine synthetase - Jannaschia sp. (strain CCS1)| Length = 393 Score = 249 bits (637), Expect = 2e-65 Identities = 157/390 (40%), Positives = 219/390 (56%), Gaps = 66/390 (16%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 MA +LFTSESV+EGHPDK+CD++SDA+LDA L+++ +++VACET TN V++ GE+ Sbjct: 1 MARNNYLFTSESVSEGHPDKVCDRISDAILDAFLSEEPEARVACETFATTNRVVIGGEVG 60 Query: 269 TK---ATVDY----EKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHF 427 +Y + IVR ++IG+ D + ++ + +QS IAQGV Sbjct: 61 LSDQDKLAEYMGQVDPIVRACVKDIGYEQDK--FHHETVEITNLLHEQSAHIAQGVDAAE 118 Query: 428 TKRPEEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK---EHVIKP----- 571 K + GAGDQGIMFG+A ETPELMP +H + KL K + V+ P Sbjct: 119 NK---DEGAGDQGIMFGFAVAETPELMPAPIHYAHAILKKLAEVRKSGEQAVLGPDAKSQ 175 Query: 572 ----------------VIPAKYLDEN--------------------------TIFHLNPS 625 V+ ++LDE+ T +H+NP+ Sbjct: 176 LSVRYEDGTPVGVSSIVLSTQHLDESLTSDDVRAIVEPYIRGELPDGWISAETEWHVNPT 235 Query: 626 GRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIA 805 G+FVIGGP GDAGLTGRKII+DTY KDPTKVDRS AY +R AK+++A Sbjct: 236 GKFVIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYASRYLAKNVVA 295 Query: 806 SGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLK 985 +GLA RC +Q+SYAIGV +PLS++ D++ TG++ + EI + + + D P I +L Sbjct: 296 AGLAHRCTIQLSYAIGVAKPLSIYCDTHQTGQVHEAEIERALGQVMDLTPRGIRTHL--- 352 Query: 986 KGGNR--FIKTAAYGHFGR---DDADFTWE 1060 G NR + +TAAYGHFGR D F+WE Sbjct: 353 -GMNRPIYERTAAYGHFGRAAEADGGFSWE 381
>Q3IW86:METK_RHOS4 S-adenosylmethionine synthetase - Rhodobacter sphaeroides (strain| ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) Length = 388 Score = 248 bits (632), Expect = 6e-65 Identities = 157/388 (40%), Positives = 211/388 (54%), Gaps = 64/388 (16%) Frame = +2 Query: 89 MAAETFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEIT 268 M+ ++FTSESV+EGHPDKLCD+VSDAVLD LA++ ++VACET T V+V GE+ Sbjct: 1 MSRMNYVFTSESVSEGHPDKLCDRVSDAVLDTFLAEEPTARVACETFATTGRVVVGGEVG 60 Query: 269 TKATVDYEK-------IVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHF 427 ++ IVRD ++IG+ + +V + +QS IAQGV Sbjct: 61 LSDPQKLDEFMERVDGIVRDCVKDIGYEQQEFHWRT--IEVQNFLHRQSAHIAQGV---- 114 Query: 428 TKRPEEVGAGDQGIMFGYATDETPELMPL----SHVLATKLGARLK-------------- 553 ++ GAGDQGIMFGYA ETPELMP SH + +L K Sbjct: 115 ----DKDGAGDQGIMFGYACRETPELMPAPIQYSHAILRRLAEVRKSGQEPDLRPDAKSQ 170 Query: 554 ------------------------------------EHVIKPVIPAKYLDENTIFHLNPS 625 E I+ V+P ++ E T + +NP+ Sbjct: 171 LSLRYENGKPVEVRSIVLSTQHAHEEQTSDDIRAIVEPYIREVLPEGWITEATEWWVNPT 230 Query: 626 GRFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIA 805 G FVIGGP GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+++A Sbjct: 231 GTFVIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNVVA 290 Query: 806 SGLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLK 985 +GLA RC +Q+SYAIGV +PLS++VD++GTG++ +I K V + D P I +L+L Sbjct: 291 AGLAERCTLQVSYAIGVAKPLSIYVDTHGTGQVDAAQIEKAVADCMDLTPRGIREHLNLC 350 Query: 986 KGGNRFIKTAAYGHFGR---DDADFTWE 1060 + + +T+AYGHFGR D F+WE Sbjct: 351 R--PIYARTSAYGHFGRAPEADGGFSWE 376
>Q83GE4:METK_TROWT S-adenosylmethionine synthetase - Tropheryma whipplei (strain Twist)| (Whipple's bacillus) Length = 395 Score = 246 bits (627), Expect = 2e-64 Identities = 148/392 (37%), Positives = 208/392 (53%), Gaps = 66/392 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 + TSESV EGHPDKLCDQ+SDA+LD + +D +++ ET+ +V V GE++ +VD Sbjct: 2 ILTSESVTEGHPDKLCDQISDAILDGVICKDKNARAGIETIAGNGVVHVFGEVSNPDSVD 61 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE------- 445 I+R T +IG+ S+D G+D + C + +I QS +IA V+ R ++ Sbjct: 62 IPGIIRKTILDIGYTSEDAGIDGNTCSIQESITSQSKEIADAVNFSLEYRNQQGDLGRNS 121 Query: 446 ---VGAGDQGIMFGYATDETPELMPL----SHVLA------------------------- 529 G+GDQG +FGYA ETPE+MPL +H LA Sbjct: 122 FSQQGSGDQGSVFGYACRETPEMMPLPITIAHKLAYSLAFVRKEKILPYLLPDGKSQVTL 181 Query: 530 --------------------------TKLGARLKEHVIKPVIPAKYLD-ENTIFHLNPSG 628 KL + E V++PVI A LD F +NP+G Sbjct: 182 GYDSANRPKTLETVVISAQHEDSVDLDKLRFDILERVVRPVISATGLDCSKATFLINPAG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFV GGP D+GLTGRKI++DTY KDP+K+DR +Y+AR AK ++A+ Sbjct: 242 RFVTGGPSADSGLTGRKIVVDTYGCAAKHGGGALSGKDPSKLDRFASYMARWVAKHVVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 A VQISYAIG P++ +D++GT I ++ + + + FDFRP + +LDLK+ Sbjct: 302 DFAESIEVQISYAIGKAHPVAFNIDTHGTNTIALDKLKRAILKVFDFRPAAVIDSLDLKR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVVKPLKFD 1084 + KTAAYGHFGRD FTWE + P K + Sbjct: 362 --PIYQKTAAYGHFGRD--IFTWERICPDKLN 389
>O67222:METK_AQUAE S-adenosylmethionine synthetase - Aquifex aeolicus| Length = 376 Score = 244 bits (623), Expect = 7e-64 Identities = 142/375 (37%), Positives = 202/375 (53%), Gaps = 54/375 (14%) Frame = +2 Query: 116 SESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVDYEK 295 +ESV EGHPDK+ DQ++DA+LD + +D SKV+ E + T +VMV GE+TT++ VD + Sbjct: 7 AESVTEGHPDKIADQLADALLDEFIKKDPYSKVSLEIMVTTGLVMVGGELTTESYVDIPR 66 Query: 296 IVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQGIMF 475 +VR ++IG+ ++G DAD C V+ +I++QSP+IA G+ GAGD I+ Sbjct: 67 VVRSVIKDIGYTRPELGFDADTCAVVQSIDEQSPEIALGISSE--------GAGDTAIVV 118 Query: 476 GYATDETPELMP----LSHVLATKLGARLK------------------------------ 553 GYAT E P LMP ++H + ++ K Sbjct: 119 GYATKEAPNLMPWPITIAHKITKRISEYRKIGKFPFLRPDGKVLVAMIYEDGKPSYVQSI 178 Query: 554 --------------------EHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAGLTG 673 E +IK IP ++L E T +NP+GRFVIGGP D GLTG Sbjct: 179 VAYVHHDPDVSINHLRELIIEEIIKKEIPEEFLTEKTSIKVNPTGRFVIGGPVADTGLTG 238 Query: 674 RKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAIG 853 RKI+ D Y KDPTK DRSG+Y+AR AK ++A G A RC+VQI YA G Sbjct: 239 RKIVSDAYGDIGLSGGSAFSGKDPTKTDRSGSYLARMIAKHVVAGGWAERCLVQIGYAFG 298 Query: 854 VPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYGHFG 1033 + EP++ ++++GT KI + VK+ F RP I LDL+K R +T+ YGHFG Sbjct: 299 LTEPVAFDIETFGTEKISKEILEDAVKKVFPLRPAEIIEFLDLRKPIYR--QTSVYGHFG 356 Query: 1034 RDDADFTWEVVKPLK 1078 ++ + WE + L+ Sbjct: 357 KE--NLPWEKLTKLE 369
>Q83HT7:METK_TROW8 S-adenosylmethionine synthetase - Tropheryma whipplei (strain| TW08/27) (Whipple's bacillus) Length = 395 Score = 244 bits (622), Expect = 9e-64 Identities = 148/392 (37%), Positives = 207/392 (52%), Gaps = 66/392 (16%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 + TSESV EGHPDKLCDQ+SDA+LD + +D +++ ET+ +V V GE++ +VD Sbjct: 2 ILTSESVTEGHPDKLCDQISDAILDGVICKDKNARAGIETIAGNGVVHVFGEVSNPDSVD 61 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEE------- 445 I+R T +IG+ S+D G+D + C + +I QS +IA V+ R ++ Sbjct: 62 IPGIIRKTILDIGYTSEDAGIDGNTCSIQESITSQSKEIADAVNFSLEYRNQQGDLGRNS 121 Query: 446 ---VGAGDQGIMFGYATDETPELMPL----SHVLA------------------------- 529 G+GDQG +FGYA ETPE+MPL +H LA Sbjct: 122 FSQQGSGDQGSVFGYACRETPEMMPLPITIAHKLAYSLAFVRKEKILPYLLPDGKSQVTL 181 Query: 530 --------------------------TKLGARLKEHVIKPVIPAKYLD-ENTIFHLNPSG 628 KL + E V++PVI A LD F +NP+G Sbjct: 182 GYDSANRPKTLETVVISAQHEDSVDLDKLRFDILERVVRPVISATGLDCSKATFLINPAG 241 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 RFV GGP D+GLTGRKI++DTY KDP+K+DR +Y+AR AK ++A+ Sbjct: 242 RFVTGGPSADSGLTGRKIVVDTYGCAAKHGGGALSGKDPSKLDRFASYMARWVAKHVVAA 301 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 A VQISYAIG P++ +D++GT I ++ + + FDFRP + +LDLK+ Sbjct: 302 DFAESIEVQISYAIGKAHPVAFNIDTHGTSTIALDKLKCAILKVFDFRPAAVIDSLDLKR 361 Query: 989 GGNRFIKTAAYGHFGRDDADFTWEVVKPLKFD 1084 + KTAAYGHFGRD FTWE + P K + Sbjct: 362 --PIYQKTAAYGHFGRD--IFTWERICPDKLN 389
>Q5FSK6:METK_GLUOX S-adenosylmethionine synthetase - Gluconobacter oxydans| (Gluconobacter suboxydans) Length = 394 Score = 242 bits (618), Expect = 3e-63 Identities = 155/381 (40%), Positives = 207/381 (54%), Gaps = 62/381 (16%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 FLFTSESV+EGHPDK+ D++SD VLDA L D +++VACET+ TN V++ GE+ V Sbjct: 7 FLFTSESVSEGHPDKVADRISDTVLDAYLQADPEARVACETLVTTNRVILAGEVRGPKEV 66 Query: 284 DYEKI--VRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAG 457 + I R+ ++IG+ D G + + + QS DIAQGV K + GAG Sbjct: 67 EDTLIDRAREAIKDIGY--DQEGFSWKKADITSYLHAQSADIAQGVDSGSDK---DEGAG 121 Query: 458 DQGIMFGYATDETPELMPLSHVLATKLGARLKEHV-------------IKPVIPAKYLD- 595 DQGIMFGYAT ET LMP A + R++++ K + +Y+D Sbjct: 122 DQGIMFGYATRETEHLMPAPLYYAQTILERIRDYRKNGDARGVGLLPDAKSQVTLRYVDG 181 Query: 596 -------------------ENTI----------------------FHLNPSGRFVIGGPH 652 +NTI F++NP+G FVIGGP Sbjct: 182 KPVGVTSVVISTQHVEGMSQNTIRETLRDVVNGILPEGWTCPEDEFYVNPTGNFVIGGPD 241 Query: 653 GDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIV 832 GDAGLTGRKII+DTY KDPTKVDRS AY AR AK+++A+GLA RC + Sbjct: 242 GDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNVVAAGLADRCTI 301 Query: 833 QISYAIGVPEPLSVFVDSYGTGK-IPDREILKLVKENFDFRPGMISINLDLKKGGNRFIK 1009 Q+SYAIGV +PLSV+VD GTGK + + + ++ E D P I +L L + ++ Sbjct: 302 QLSYAIGVSKPLSVYVDLDGTGKDVDEARLGAILNEVVDLSPRGIRKHLRLNR--PIYVP 359 Query: 1010 TAAYGHFGRDD----ADFTWE 1060 T+AYGHFGR +FTWE Sbjct: 360 TSAYGHFGRAPDPVLDNFTWE 380
>Q8D2N8:METK_WIGBR S-adenosylmethionine synthetase - Wigglesworthia glossinidia| brevipalpis Length = 385 Score = 241 bits (614), Expect = 7e-63 Identities = 147/381 (38%), Positives = 213/381 (55%), Gaps = 51/381 (13%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQ+SD +LDA L QD ++VACET KT MV+V GE+ + A + Sbjct: 4 YLFTSESVSEGHPDKIADQISDTILDAILTQDKKARVACETYIKTGMVLVGGEVNSYAKI 63 Query: 284 DYEKIVRDTCR-------NIGFISDDVGLDADRCKVLVNIEQ---QSPDIAQG------V 415 D E+++R+T + N+GF ++ + + K +IE+ Q QG + Sbjct: 64 DIEELIRNTIKDIGYINSNMGFDANSCAILNNISKQSKDIEKGLNQLDPYMQGAGDQGII 123 Query: 416 HGHFTKRPE----------------EVGAGDQGIMFGYATD---------ETPELMPLSH 520 G+ T E + + I+ D E +++ + Sbjct: 124 FGYATNETETFMPAPITYANKLMIRQSEVRKKNILPWLRPDAKSQITFIYENKKIVGIDT 183 Query: 521 VLATK----------LGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAGLT 670 V+ + L + E +I+P++P K++ T + +NP+GRFVIGGP GD GLT Sbjct: 184 VIISSQHSEEINLSDLREGIMEEIIQPILPKKWISNKTKYFINPTGRFVIGGPMGDCGLT 243 Query: 671 GRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISYAI 850 GRKII+DTY KDP+KVDRS AY R AK+I+ASGLA RC +QISYAI Sbjct: 244 GRKIIVDTYGGMARHGGGSFSGKDPSKVDRSAAYALRYVAKNIVASGLADRCEIQISYAI 303 Query: 851 GVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYGHF 1030 GV P+S+F++++GT KI +++++ L+ ENFD RP + + LDL K R +TA YGHF Sbjct: 304 GVSNPISIFIETFGTQKISNKKLINLIHENFDLRPHGLIVMLDLLKPIYR--ETAVYGHF 361 Query: 1031 GRDDADFTWEVVKPLKFDKAS 1093 + F WE K DKA+ Sbjct: 362 SK--IHFPWE-----KIDKAN 375
>P31156:METL_PETCR S-adenosylmethionine synthetase 2 - Petroselinum crispum (Parsley)| (Petroselinum hortense) Length = 145 Score = 238 bits (608), Expect = 4e-62 Identities = 119/145 (82%), Positives = 128/145 (88%), Gaps = 1/145 (0%) Frame = +2 Query: 659 AGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQI 838 AGLTGRKIIIDTY KDPTKVDRSGAYI RQAAKSI+ASGLARRCIVQ+ Sbjct: 1 AGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASGLARRCIVQV 60 Query: 839 SYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGN-RFIKTA 1015 SYAIGVPEPLSVFVDSYGTGKIPDREIL++VKE FDFRPGMISINLDLK+GGN RF+KTA Sbjct: 61 SYAIGVPEPLSVFVDSYGTGKIPDREILQIVKETFDFRPGMISINLDLKRGGNGRFLKTA 120 Query: 1016 AYGHFGRDDADFTWEVVKPLKFDKA 1090 AYGHFGR+D DFTWEVVKPLK++KA Sbjct: 121 AYGHFGREDPDFTWEVVKPLKWEKA 145
>Q5NQV7:METK_ZYMMO S-adenosylmethionine synthetase - Zymomonas mobilis| Length = 391 Score = 237 bits (604), Expect = 1e-61 Identities = 146/381 (38%), Positives = 211/381 (55%), Gaps = 62/381 (16%) Frame = +2 Query: 104 FLFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATV 283 +LFTSESV+EGHPDK+ DQ+SDA++D L++D +++VACET+ T +++ GE+ + V Sbjct: 5 YLFTSESVSEGHPDKVADQISDAIVDLYLSRDPEARVACETLVTTQRIIIGGEVRSAVPV 64 Query: 284 ---DYEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGA 454 + EK VR+T R IG+ + G D + ++ QS DIAQGV K + GA Sbjct: 65 SEEEIEKTVRETVREIGY--EQTGFDWRTAEFANHLHAQSADIAQGVDAGEDK---DEGA 119 Query: 455 GDQGIMFGYAT----DETPELMPLSHVLATKLG--------------------------- 541 GDQGIMFG+AT D P + +H + +L Sbjct: 120 GDQGIMFGFATDETPDYMPATLYYAHRILERLAEDRHQKKVDFLEPDAKSQVTLVYENGV 179 Query: 542 -----------------------ARLKEHV---IKPVIPAKYLDENTIFHLNPSGRFVIG 643 A+L+++V + V+P ++ ++ +NP+G F IG Sbjct: 180 PVRASALVLSTQHSPALSSKEGQAKLRDYVKSVYEDVLPKGWMPDDKAIFVNPTGLFEIG 239 Query: 644 GPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARR 823 GP GDAGLTGRKII+DTY KDPTKVDRS AY+AR AK+I+A+GLA++ Sbjct: 240 GPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYVARYLAKNIVAAGLAKK 299 Query: 824 CIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRF 1003 +Q+SYAIGV EPLS++VD++GTG + + +I +++ + P I +L L K + Sbjct: 300 VTIQLSYAIGVSEPLSLYVDTHGTGTVDEAKIEEVLPKLIRLTPKGIRTHLKLNK--PIY 357 Query: 1004 IKTAAYGHFGR--DDADFTWE 1060 +AAYGHFGR D F WE Sbjct: 358 KPSAAYGHFGRKADGDFFPWE 378
>Q7WYN1:METK_MYCSM S-adenosylmethionine synthetase - Mycobacterium smegmatis| Length = 399 Score = 234 bits (597), Expect = 7e-61 Identities = 156/384 (40%), Positives = 199/384 (51%), Gaps = 66/384 (17%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV EGHPDK+CD +SD+VLDA L QD S+VA ET+ T V V GE+TT A D Sbjct: 6 LFTSESVTEGHPDKICDAISDSVLDALLEQDPKSRVAVETLVTTGQVHVAGEVTTTAYAD 65 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEV------ 448 KIVRD +IG+ S G D C V V I QSPDIAQGV R E Sbjct: 66 IPKIVRDRILDIGYDSSTKGFDGASCGVNVAIGAQSPDIAQGVDTAHETRVEGKADPLDL 125 Query: 449 -GAGDQ----GIMFGYATDETPELMPLSH------------------------------- 520 GAGDQ G G + P + L+H Sbjct: 126 QGAGDQGLMFGYAIGDTPELMPLPIALAHRLARRLTEVRKNGVLDYLRPDGKTQVTIQYD 185 Query: 521 ----------VLATK----------LGARLKEHVIKPVIPA---KYLDENTIFHL-NPSG 628 VL+T+ L ++E V+ V+ + LD + L NP+G Sbjct: 186 GTTPVRLDTVVLSTQHADGIDLEGTLTPDIREKVVNTVLADLGHETLDTSDYRLLVNPTG 245 Query: 629 RFVIGGPHGDAGLTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIAS 808 +FV+GGP GDAGLTGRKII+DTY KDP+KVDRS AY R AK+++A+ Sbjct: 246 KFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAA 305 Query: 809 GLARRCIVQISYAIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKK 988 GLA R VQ++YAIG P+ +FV+++G+ + +I K + E FD RP I +LDL + Sbjct: 306 GLAERVEVQVAYAIGKAAPVGLFVETFGSETVDPAKIEKAIGEVFDLRPAAIVRDLDLLR 365 Query: 989 GGNRFIKTAAYGHFGRDDADFTWE 1060 + TAAYGHFGR D + WE Sbjct: 366 --PIYAPTAAYGHFGRTDIELPWE 387
>Q98PM0:METK_MYCPU S-adenosylmethionine synthetase - Mycoplasma pulmonis| Length = 376 Score = 232 bits (592), Expect = 3e-60 Identities = 137/372 (36%), Positives = 196/372 (52%), Gaps = 54/372 (14%) Frame = +2 Query: 107 LFTSESVNEGHPDKLCDQVSDAVLDACLAQDADSKVACETVTKTNMVMVLGEITTKATVD 286 LFTSESV GHPDK+CDQ+SD++LDA L D +S+ A E + ++++ GEITT+ VD Sbjct: 5 LFTSESVGRGHPDKICDQISDSILDAVLKIDPNSRCAIEVMASNRLIIIGGEITTQGYVD 64 Query: 287 YEKIVRDTCRNIGFISDDVGLDADRCKVLVNIEQQSPDIAQGVHGHFTKRPEEVGAGDQG 466 + ++G+ +D ++ N+ +QS +IA V ++ + +GAGDQG Sbjct: 65 LVSKSWEILISLGYTENDF-------TIISNVNEQSKEIANQVD----RQDDNIGAGDQG 113 Query: 467 IMFGYATDETPELMP--------------------------------------------- 511 IMFG+A+DET MP Sbjct: 114 IMFGFASDETKSFMPLAISIAHDLVKRAEKLRVENKINGLKSDMKSQVTIDYSDQKNPKI 173 Query: 512 ------LSH---VLATKLGARLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAG 664 L H VL +K+ +I+PV+ L+ N +NP+G F IGGP GD G Sbjct: 174 DTILMSLQHDKDVLLDNFRNDVKKLIIEPVVNDYNLNSNYKCFINPNGSFSIGGPIGDTG 233 Query: 665 LTGRKIIIDTYXXXXXXXXXXXXXKDPTKVDRSGAYIARQAAKSIIASGLARRCIVQISY 844 LTGRKII+DTY KD TKVDRS AY+AR AK+++A+ +A++ +Q+SY Sbjct: 234 LTGRKIIVDTYGGAAHHGGGAFSGKDYTKVDRSAAYMARYIAKNLVAAKVAKKLEIQLSY 293 Query: 845 AIGVPEPLSVFVDSYGTGKIPDREILKLVKENFDFRPGMISINLDLKKGGNRFIKTAAYG 1024 IG+ EP+S+ V+S+GT K D EI ++ NF P I L+LK ++ T+ +G Sbjct: 294 GIGMIEPISINVNSFGTSKFSDLEITDFIRNNFSLSPKSIIEKLNLK--NTKYFPTSFFG 351 Query: 1025 HFGRDDADFTWE 1060 HFGRDD D WE Sbjct: 352 HFGRDDLDLPWE 363 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 239,995,851 Number of extensions: 5377662 Number of successful extensions: 20231 Number of sequences better than 10.0: 297 Number of HSP's gapped: 19600 Number of HSP's successfully gapped: 579 Length of query: 485 Length of database: 100,686,439 Length adjustment: 117 Effective length of query: 368 Effective length of database: 68,593,924 Effective search space: 25242564032 Effective search space used: 25242564032 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
