ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf45c03 |
|---|---|
| Clone Library Name | barley_pub |
>Q9SZJ5:GLYM_ARATH Serine hydroxymethyltransferase, mitochondrial precursor -| Arabidopsis thaliana (Mouse-ear cress) Length = 517 Score = 868 bits (2244), Expect = 0.0 Identities = 440/518 (84%), Positives = 470/518 (90%), Gaps = 8/518 (1%) Frame = +3 Query: 87 MAMATALRKLSARG----QPLSRLTPLYSMASLPAT----EERSAVTWPKQLNAPLEEVD 242 MAMA ALR+LS+ +PL R T Y M+SLP+ +ERS VTWPKQLNAPLEEVD Sbjct: 1 MAMAMALRRLSSSIDKPIRPLIRSTSCY-MSSLPSEAVDEKERSRVTWPKQLNAPLEEVD 59 Query: 243 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 422 PEIADIIE EKARQWKGLELIPSENFTS+SVMQAVGSVMTNKYSEGYPGARYYGGNEYID Sbjct: 60 PEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 119 Query: 423 MAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHLS 602 MAETLCQKRALEAF LDPEKWGVNVQPLSGSPANFHVYTALLKPH+RIMALDLPHGGHLS Sbjct: 120 MAETLCQKRALEAFRLDPEKWGVNVQPLSGSPANFHVYTALLKPHERIMALDLPHGGHLS 179 Query: 603 HGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLYD 782 HGYQTDTKKISAVSIFFETMPYRLDESTG IDYDQ+EKSA LFRPKLIVAGASAYARLYD Sbjct: 180 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQMEKSATLFRPKLIVAGASAYARLYD 239 Query: 783 YNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFR 962 Y R+RK+C+KQKAV+LADMAHISGLVAA VIPSPF+YADVVTTTTHKSLRGPRGAMIFFR Sbjct: 240 YARIRKVCNKQKAVMLADMAHISGLVAANVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 299 Query: 963 KGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQV 1142 KGVKEINKQGKEV YDFEDKIN AVFPGLQGGPHNHTITGLAVALKQATT EY+AYQEQV Sbjct: 300 KGVKEINKQGKEVLYDFEDKINQAVFPGLQGGPHNHTITGLAVALKQATTSEYKAYQEQV 359 Query: 1143 MSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVPG 1322 +SNSA+FA++L +GY++VSGGTDNHLVLVNLK KGIDGSRVEKVLE VHIA+NKNTVPG Sbjct: 360 LSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVHIASNKNTVPG 419 Query: 1323 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFVATL 1502 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAE+FD GTKLKDFV+ + Sbjct: 420 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSEAQGTKLKDFVSAM 479 Query: 1503 QSDSNIQAEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 1616 +S S IQ+EIAKLRH+VEE+AKQFPTIGFEKETMKYKN Sbjct: 480 ESSSTIQSEIAKLRHEVEEFAKQFPTIGFEKETMKYKN 517
>P49357:GLYM_FLAPR Serine hydroxymethyltransferase 1, mitochondrial precursor - Flaveria| pringlei Length = 517 Score = 863 bits (2231), Expect = 0.0 Identities = 441/518 (85%), Positives = 467/518 (90%), Gaps = 8/518 (1%) Frame = +3 Query: 87 MAMATALRKLSARG-QPLSRLTP---LYSMASLPAT----EERSAVTWPKQLNAPLEEVD 242 MAMA ALR+LS+ +PL RL LYSM+SLP+ +ER VTWPKQLNAPLE VD Sbjct: 1 MAMALALRRLSSSADKPLQRLFNGGHLYSMSSLPSEAVYEKERPGVTWPKQLNAPLEVVD 60 Query: 243 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 422 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID Sbjct: 61 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 120 Query: 423 MAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHLS 602 MAETLCQKRALEAF LDP KWGVNVQPLSGSPANFHVYTALLK HDRIMALDLPHGGHLS Sbjct: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALDLPHGGHLS 180 Query: 603 HGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLYD 782 HGYQTDTKKISAVSIFFETMPYRL+ESTG IDYDQLEKSA LFRPKLIVAGASAYARLYD Sbjct: 181 HGYQTDTKKISAVSIFFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240 Query: 783 YNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFR 962 Y R+RK+CDKQKA++LADMAHISGLVAAGVIPSPF+YADVVTTTTHKSLRGPRGAMIFFR Sbjct: 241 YARIRKVCDKQKAIMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300 Query: 963 KGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQV 1142 KG+KE+NKQGKEV YD+EDKIN AVFPGLQGGPHNHTITGLAVALKQATT EY+AYQEQV Sbjct: 301 KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTAEYKAYQEQV 360 Query: 1143 MSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVPG 1322 MSNSA+FAE+L GY++VSGGT+NHLVLVNLK KGIDGS+VEKVLE VHIAANKNTVPG Sbjct: 361 MSNSAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSKVEKVLEAVHIAANKNTVPG 420 Query: 1323 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFVATL 1502 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVA FFD GTKLKDFV + Sbjct: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYFFDLAVKLAVKIKGEAKGTKLKDFVTAM 480 Query: 1503 QSDSNIQAEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 1616 +S S IQ+EI+KLRHDVEEYAKQFPTIGFEKETMKYKN Sbjct: 481 ES-SAIQSEISKLRHDVEEYAKQFPTIGFEKETMKYKN 517
>P50433:GLYM_SOLTU Serine hydroxymethyltransferase, mitochondrial precursor - Solanum| tuberosum (Potato) Length = 518 Score = 861 bits (2225), Expect = 0.0 Identities = 436/518 (84%), Positives = 468/518 (90%), Gaps = 8/518 (1%) Frame = +3 Query: 87 MAMATALRKLSAR-GQPLSRLT---PLYSMASLPAT----EERSAVTWPKQLNAPLEEVD 242 MAMA ALR+LSA +P+ L LY M+SLP +E+S V WPKQLNAPLE VD Sbjct: 1 MAMAIALRRLSATVDKPVKSLYNGGSLYYMSSLPNEAVYDKEKSGVAWPKQLNAPLEVVD 60 Query: 243 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 422 PEIADIIE EKARQWKGLELIPSENFTS+SVMQAVGSVMTNKYSEGYPGARYYGGNEYID Sbjct: 61 PEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 120 Query: 423 MAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHLS 602 MAETLCQKRALEAF LDP KWGVNVQPLSGSPANF VYTALLKPH+RIMALDLPHGGHLS Sbjct: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFQVYTALLKPHERIMALDLPHGGHLS 180 Query: 603 HGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLYD 782 HGYQTDTKKISAVSIFFETMPYRLDESTG IDYDQLEKSA LFRPKLIVAGASAYARLYD Sbjct: 181 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240 Query: 783 YNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFR 962 Y+R+RK+C+KQKA+LLADMAHISGLVAAGVIPSPF+YADVVTTTTHKSLRGPRGAMIF+R Sbjct: 241 YDRIRKVCNKQKAILLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFYR 300 Query: 963 KGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQV 1142 KGVKE+NKQGKEV YD+EDKIN AVFPGLQGGPHNHTITGLAVALKQATT EYRAYQEQV Sbjct: 301 KGVKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYRAYQEQV 360 Query: 1143 MSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVPG 1322 +SNS++FA++L KGY++VSGGTDNHLVLVN+K KGIDGSRVEKVLE VHIAANKNTVPG Sbjct: 361 LSNSSKFAQALGEKGYELVSGGTDNHLVLVNMKNKGIDGSRVEKVLEAVHIAANKNTVPG 420 Query: 1323 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFVATL 1502 DVSAMVPGGIRMGTPALTSRGF+EEDF KVA+FFD+ GTKLKDFVATL Sbjct: 421 DVSAMVPGGIRMGTPALTSRGFLEEDFVKVADFFDAAVKIAVKVKAETQGTKLKDFVATL 480 Query: 1503 QSDSNIQAEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 1616 +S + I++EIAKLRHDVEEYAKQFPTIGFEKETMKYKN Sbjct: 481 ESSAPIKSEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 518
>P34899:GLYM_PEA Serine hydroxymethyltransferase, mitochondrial precursor - Pisum| sativum (Garden pea) Length = 518 Score = 856 bits (2212), Expect = 0.0 Identities = 432/516 (83%), Positives = 462/516 (89%), Gaps = 8/516 (1%) Frame = +3 Query: 87 MAMATALRKLSAR----GQPLSRLTPLYSMASLPAT----EERSAVTWPKQLNAPLEEVD 242 MAMA ALRKLS+ +PL + LY +SLP +E VTWPKQLN+PLE +D Sbjct: 1 MAMAMALRKLSSSVNKSSRPLFSASSLYYKSSLPDEAVYDKENPRVTWPKQLNSPLEVID 60 Query: 243 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 422 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID Sbjct: 61 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 120 Query: 423 MAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHLS 602 MAETLCQKRALEAF LDP KWGVNVQPLSGSP+NF VYTALLKPHDRIMALDLPHGGHLS Sbjct: 121 MAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFQVYTALLKPHDRIMALDLPHGGHLS 180 Query: 603 HGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLYD 782 HGYQTDTKKISAVSIFFETMPYRLDESTG IDYDQLEKSA LFRPKLIVAGASAYARLYD Sbjct: 181 HGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240 Query: 783 YNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFR 962 Y R+RK+CDKQKAVLLADMAHISGLVAAGVIPSPF+YADVVTTTTHKSLRGPRGAMIFFR Sbjct: 241 YARIRKVCDKQKAVLLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300 Query: 963 KGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQV 1142 KG+KE+NKQGKEV YD+EDKIN AVFPGLQGGPHNHTITGLAVALKQATT EYRAYQEQV Sbjct: 301 KGLKEVNKQGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTPEYRAYQEQV 360 Query: 1143 MSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVPG 1322 +SNS++FA++L+ KGYD+VSGGT+NHLVLVNLK KGIDGSRVEKVLE VHIAANKNTVPG Sbjct: 361 LSNSSKFAKALSEKGYDLVSGGTENHLVLVNLKNKGIDGSRVEKVLELVHIAANKNTVPG 420 Query: 1323 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFVATL 1502 DVSAMVPGGIRMGTPALTSRGFVEEDF KVAE+FD+ GTKLKDFV L Sbjct: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDAAVSLALKVKAESKGTKLKDFVEAL 480 Query: 1503 QSDSNIQAEIAKLRHDVEEYAKQFPTIGFEKETMKY 1610 Q+ S +Q+EI+KL+HDVEE+AKQFPTIGFEK TMKY Sbjct: 481 QTSSYVQSEISKLKHDVEEFAKQFPTIGFEKATMKY 516
>P49358:GLYN_FLAPR Serine hydroxymethyltransferase 2, mitochondrial precursor - Flaveria| pringlei Length = 517 Score = 855 bits (2209), Expect = 0.0 Identities = 440/518 (84%), Positives = 463/518 (89%), Gaps = 8/518 (1%) Frame = +3 Query: 87 MAMATALRKLSARG-QPLSRLTP---LYSMASLPAT----EERSAVTWPKQLNAPLEEVD 242 MAMA+ALR+LS+ +PL RL LYSM+SLP+ +ER VTWPKQLNAPLE D Sbjct: 1 MAMASALRRLSSSSNKPLQRLFNGGHLYSMSSLPSEAVYEKERPGVTWPKQLNAPLEVGD 60 Query: 243 PEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 422 PEIADIIELEKARQWKGLELI SENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID Sbjct: 61 PEIADIIELEKARQWKGLELILSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYID 120 Query: 423 MAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHLS 602 MAETLCQKRALEAF LD KWGVNVQPLSGSPANFHVYTALLK HDRIMALDLPHGGHLS Sbjct: 121 MAETLCQKRALEAFRLDAAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALDLPHGGHLS 180 Query: 603 HGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLYD 782 HGYQTDTKKISAVSIFFETMPYRL+ESTG IDYDQLEKSA LFRPKLIVAGASAYARLYD Sbjct: 181 HGYQTDTKKISAVSIFFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAGASAYARLYD 240 Query: 783 YNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFR 962 Y R+RK+CDKQKA+LLADMAHISGLVAAGVIPSPF+YADVVTTTTHKSLRGPRGAMIFFR Sbjct: 241 YARIRKVCDKQKAILLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRGPRGAMIFFR 300 Query: 963 KGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQV 1142 KGVKE+NKQGKEV YD+EDKIN AVFPGLQGGPHNHTITGLAVALKQATT EY+AYQEQV Sbjct: 301 KGVKEVNKQGKEVLYDYEDKINQAVFPGLQGGPHNHTITGLAVALKQATTAEYKAYQEQV 360 Query: 1143 MSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVPG 1322 MSN A+FAE+L GY++VSGGT+NHLVLVNLK KGIDGSRVEKVLE VHIAANKNTVPG Sbjct: 361 MSNCAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSRVEKVLEAVHIAANKNTVPG 420 Query: 1323 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFVATL 1502 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVA FD GTKLKDFVA + Sbjct: 421 DVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYLFDLAVKLAVKIKGEAQGTKLKDFVAAM 480 Query: 1503 QSDSNIQAEIAKLRHDVEEYAKQFPTIGFEKETMKYKN 1616 QS S Q+EI+KLRHDVEEYAKQFPTIGFEKETMKYKN Sbjct: 481 QS-SAFQSEISKLRHDVEEYAKQFPTIGFEKETMKYKN 517
>Q10104:GLYC_SCHPO Probable serine hydroxymethyltransferase, cytosolic -| Schizosaccharomyces pombe (Fission yeast) Length = 472 Score = 576 bits (1484), Expect = e-163 Identities = 289/458 (63%), Positives = 351/458 (76%), Gaps = 3/458 (0%) Frame = +3 Query: 210 KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPG 389 K L APL E DP + I+E EK+RQ + + LI SENFTS +VM A+GS+M NKYSEGYPG Sbjct: 12 KLLKAPLAECDPTVYKILESEKSRQKESIALIASENFTSRAVMDALGSIMQNKYSEGYPG 71 Query: 390 ARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIM 569 ARYYGGNE+ID AE LCQ RALEAF+LD EKWGVNVQP SGSPAN Y A++KPHDR+M Sbjct: 72 ARYYGGNEFIDQAERLCQTRALEAFHLDGEKWGVNVQPHSGSPANLQAYQAVMKPHDRLM 131 Query: 570 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIV 749 LDLPHGGHLSHG+ T K ISAVS +F TMPY +++ TG+IDYD LEK+A+ FRPK+IV Sbjct: 132 GLDLPHGGHLSHGFSTPQKAISAVSTYFSTMPYNVNKETGIIDYDSLEKAAIQFRPKVIV 191 Query: 750 AGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSL 929 AGASAYARL DY RMRKI + A LL DMAHISGLVAAGVIPSPFEYAD+VTTTTHKSL Sbjct: 192 AGASAYARLVDYKRMRKITEMCNAYLLCDMAHISGLVAAGVIPSPFEYADIVTTTTHKSL 251 Query: 930 RGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQAT 1109 RGPRGAMIF+RKG + +K+G + Y+ EDKIN +VFPG QGGPHNHTIT LAVAL QA Sbjct: 252 RGPRGAMIFYRKGTRSHDKRGNPILYELEDKINFSVFPGHQGGPHNHTITALAVALGQAK 311 Query: 1110 TQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENV 1289 T E+ YQ+ V+SN+ A + ++GY +VSGGTD HLVLV+L KG+DG+RVE++LE V Sbjct: 312 TPEFYQYQKDVLSNAKAMANAFITRGYKLVSGGTDTHLVLVDLTDKGVDGARVERILELV 371 Query: 1290 HIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD---SXXXXXXXXXX 1460 +I+ANKNTVPGD SA++P G+R+GTPA T+RGF E+DF +V E D S Sbjct: 372 NISANKNTVPGDKSALIPRGLRLGTPACTTRGFDEKDFERVVELIDEVVSLTKKINEAAL 431 Query: 1461 XXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQF 1574 +K +DF A + D + +EIAKL+ +V +A +F Sbjct: 432 KEGKSKFRDFKAYV-GDGSKFSEIAKLKKEVITWAGKF 468
>P34897:GLYM_HUMAN Serine hydroxymethyltransferase, mitochondrial precursor - Homo| sapiens (Human) Length = 504 Score = 568 bits (1463), Expect = e-161 Identities = 290/496 (58%), Positives = 362/496 (72%), Gaps = 7/496 (1%) Frame = +3 Query: 129 QPLSRLTPLYSMASLPATEERSAVTWPKQLNA------PLEEVDPEIADIIELEKARQWK 290 +PL R L MA + A +A T + N L + DPE+ ++++ EK RQ + Sbjct: 11 RPLQRCGQLVRMA-IRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCR 69 Query: 291 GLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNL 470 GLELI SENF S + ++A+GS + NKYSEGYPG RYYGG E +D E LCQ+RALEAF+L Sbjct: 70 GLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDL 129 Query: 471 DPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIF 650 DP +WGVNVQP SGSPAN VYTALL+PHDRIM LDLP GGHL+HGY +D K+ISA SIF Sbjct: 130 DPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIF 189 Query: 651 FETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLL 830 FE+MPY+L+ TGLIDY+QL +A LFRP+LI+AG SAYARL DY RMR++CD+ KA LL Sbjct: 190 FESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLL 249 Query: 831 ADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFRKGVKEIN-KQGKEVKY 1007 ADMAHISGLVAA VIPSPF++AD+VTTTTHK+LRG R +IF+RKGVK ++ K G+E+ Y Sbjct: 250 ADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPY 309 Query: 1008 DFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKG 1187 FED+IN AVFP LQGGPHNH I +AVALKQA T +R Y QV+ N+ A++L +G Sbjct: 310 TFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERG 369 Query: 1188 YDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVPGDVSAMVPGGIRMGTP 1367 Y +VSGGTDNHLVLV+L+ KG+DG+R E+VLE V I ANKNT PGD SA+ PGG+R+G P Sbjct: 370 YSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAP 429 Query: 1368 ALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFVATLQSDSNIQAEIAKLRH 1547 ALTSR F E+DF +V +F D KL+DF + L DS +A LR Sbjct: 430 ALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT--AKLQDFKSFLLKDSETSQRLANLRQ 487 Query: 1548 DVEEYAKQFPTIGFEK 1595 VE++A+ FP GF++ Sbjct: 488 RVEQFARAFPMPGFDE 503
>O13425:GLYM_CANAL Serine hydroxymethyltransferase, mitochondrial precursor - Candida| albicans (Yeast) Length = 493 Score = 568 bits (1463), Expect = e-161 Identities = 281/476 (59%), Positives = 357/476 (75%), Gaps = 3/476 (0%) Frame = +3 Query: 168 SLPATEERSAVTWPKQ---LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVM 338 +LPA R+ P ++ +++VDPE+ADI+ E+ RQ + LIPSENFTS +VM Sbjct: 16 NLPAFARRTYAVSPSAQALISKSVQDVDPEMADILNQERTRQKNSITLIPSENFTSKAVM 75 Query: 339 QAVGSVMTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSP 518 +GS M NKYSEGYPG RYYGGNE ID AE LCQKRALEAF LDP +WGVNVQPLSG+P Sbjct: 76 DLLGSEMQNKYSEGYPGERYYGGNEIIDKAEALCQKRALEAFGLDPSQWGVNVQPLSGAP 135 Query: 519 ANFHVYTALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLID 698 AN + Y+A+L+ DRIM LDLPHGGHLSHGYQT T KIS +S +F+TMPYRL+E TG+ID Sbjct: 136 ANLYAYSAILEVGDRIMGLDLPHGGHLSHGYQTKTTKISYISKYFQTMPYRLNEETGIID 195 Query: 699 YDQLEKSAVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIP 878 YD LEK+A LFRPK+IVAGASAY+R+ DY RMR++ + A LL+DMAHISGLV+A V Sbjct: 196 YDTLEKNAQLFRPKVIVAGASAYSRVIDYKRMRQLSIRLGAYLLSDMAHISGLVSAVVTD 255 Query: 879 SPFEYADVVTTTTHKSLRGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGG 1058 SPF Y+D+VTTTTHKSLRGPRGAMIFFRKG++++ +GKE+ Y+ E KIN VFPG QGG Sbjct: 256 SPFPYSDIVTTTTHKSLRGPRGAMIFFRKGIRKVTTKGKEIPYELERKINFLVFPGHQGG 315 Query: 1059 PHNHTITGLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNL 1238 PHNHTI+ LAVALKQ T EY YQ++V+SN+ FA++L SKG+ +VS GTD HL+LV+L Sbjct: 316 PHNHTISALAVALKQCTEPEYVKYQQEVVSNAKHFADALVSKGFKLVSDGTDTHLILVDL 375 Query: 1239 KKKGIDGSRVEKVLENVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 + + IDG+RVE VLE +IAANKNTVPGDVSA+ P G+R+GTPA+T+RGF E+F KVAE Sbjct: 376 RSRNIDGARVEAVLERANIAANKNTVPGDVSALFPSGLRVGTPAMTTRGFGPEEFDKVAE 435 Query: 1419 FFDSXXXXXXXXXXXXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 F D G K+ +A+ + ++ ++ +L +V + ++P G Sbjct: 436 FIDQAVNIAIELKAQEQGKVPKELLASFKKLADESDKVKQLDKEVVSWVSKYPVPG 491
>Q60V73:GLYC_CAEBR Serine hydroxymethyltransferase - Caenorhabditis briggsae| Length = 484 Score = 567 bits (1462), Expect = e-161 Identities = 277/453 (61%), Positives = 347/453 (76%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +E++DPE+ +I++ EK+RQ +GLELI SENFTS +VM A+GS M NKYSEGYPGARYYGG Sbjct: 29 VEKIDPEVFNIMKNEKSRQRRGLELIASENFTSKAVMDALGSAMCNKYSEGYPGARYYGG 88 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 NE+ID E LCQKRALE F LDP KWGVNVQ LSGSPANF VYTAL+ + RIM LDLP Sbjct: 89 NEFIDQMEILCQKRALEVFGLDPAKWGVNVQSLSGSPANFAVYTALVGANGRIMGLDLPD 148 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG+ T +K+SA S FF++MPY++D +GLIDYD+LE++A+LFRPK+++AG S Y Sbjct: 149 GGHLTHGFFTPARKVSATSEFFQSMPYKVDAQSGLIDYDKLEENAMLFRPKVLIAGVSCY 208 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 AR DY R RKI K A L++DMAHISGLVAAG+IPSPFEY+DVVTTTTHKSLRGPRGA Sbjct: 209 ARHLDYERFRKIATKAGAYLMSDMAHISGLVAAGLIPSPFEYSDVVTTTTHKSLRGPRGA 268 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MIF+RKGV+ +N +G E YD E+KIN+AVFPGLQGGPHNHTI G+AVALKQ ++++ Sbjct: 269 MIFYRKGVRSVNAKGVETLYDLEEKINSAVFPGLQGGPHNHTIAGIAVALKQCLSEDFVQ 328 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y EQ++ N+ AE L GY + +GGTDNHL+LV+L+ G++G+R E +L+ HIA NK Sbjct: 329 YGEQILKNAKTLAERLKKHGYSLATGGTDNHLLLVDLRPIGVEGARAEHILDLAHIACNK 388 Query: 1308 NTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKD 1487 NT PGDVSA+ PGGIR+GTPALTSRGF E+DF KV +F G LKD Sbjct: 389 NTCPGDVSALRPGGIRLGTPALTSRGFKEQDFEKVGDFIHE-GVQIAKKYNAEAGKTLKD 447 Query: 1488 FVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 F A ++ + E+A+L VEE++ +F G Sbjct: 448 FKAFTATNEQFKQEVAELAKRVEEFSGKFEIPG 480
>Q3SZ20:GLYM_BOVIN Serine hydroxymethyltransferase, mitochondrial precursor - Bos taurus| (Bovine) Length = 504 Score = 565 bits (1456), Expect = e-160 Identities = 279/456 (61%), Positives = 346/456 (75%), Gaps = 1/456 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L + DPE+ +++ EK RQ +GLELI SENF S + ++A+GS + NKYSEGYPG RYYGG Sbjct: 49 LSDSDPEMWELLRREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E +D E LCQ+RALEAF+LDP +WGVNVQP SGSPAN YTALL+PHDRIM LDLP Sbjct: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPD 168 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HGY +D K+ISA SIFFE+MPY+L+ TGLIDYDQL +A LF+P+LI+AG SAY Sbjct: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFKPRLIIAGTSAY 228 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ARL DY RMR++CD+ KA LLADMAHISGLVAA VIPSPF++AD+VTTTTHK+LRG R Sbjct: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 Query: 948 MIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 +IF+RKGV+ ++ K G+E+ Y FED+IN AVFP LQGGPHNH I +AVALKQA T +R Sbjct: 289 LIFYRKGVQAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAAN 1304 Y Q++ N+ A +L +GY +VSGGTDNHLVLV+L+ KG+DG+R E+VLE V I AN Sbjct: 349 EYSLQILKNAQAMANALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITAN 408 Query: 1305 KNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 KNT PGD SA+ PGG+R+G PALTSRGF+E+DF KV F D TKL+ Sbjct: 409 KNTCPGDRSAITPGGLRLGAPALTSRGFLEDDFRKVVGFIDEGVNIGLEVKSKT--TKLQ 466 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIGFE 1592 DF + L D ++A LR VE++A+ FP GF+ Sbjct: 467 DFKSFLLKDPETSHQLADLRQRVEQFARAFPMPGFD 502
>P50432:GLYC_CAEEL Serine hydroxymethyltransferase - Caenorhabditis elegans| Length = 507 Score = 565 bits (1455), Expect = e-160 Identities = 277/455 (60%), Positives = 347/455 (76%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +E+VDPE+ DI++ EK RQ +GLELI SENFTS +VM A+GS M NKYSEGYPGARYYGG Sbjct: 52 VEKVDPEVFDIMKNEKKRQRRGLELIASENFTSKAVMDALGSAMCNKYSEGYPGARYYGG 111 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 NE+ID E LCQKRALE F LDP KWGVNVQPLSGSPANF VYTA++ + RIM LDLP Sbjct: 112 NEFIDQMELLCQKRALEVFGLDPAKWGVNVQPLSGSPANFAVYTAIVGSNGRIMGLDLPD 171 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG+ T +K+SA S FF+++PY++D +TGLIDYD+LE++A+LFRPK I+AG S Y Sbjct: 172 GGHLTHGFFTPARKVSATSEFFQSLPYKVDPTTGLIDYDKLEQNAMLFRPKAIIAGVSCY 231 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 AR DY R RKI K A L++DMAHISGLVAAG+IPSPFEY+DVVTTTTHKSLRGPRGA Sbjct: 232 ARHLDYERFRKIATKAGAYLMSDMAHISGLVAAGLIPSPFEYSDVVTTTTHKSLRGPRGA 291 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +IF+RKGV+ N +G + YD E+KIN+AVFPGLQGGPHNHTI G+AVAL+Q ++++ Sbjct: 292 LIFYRKGVRSTNAKGVDTLYDLEEKINSAVFPGLQGGPHNHTIAGIAVALRQCLSEDFVQ 351 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y EQV+ N+ AE + GY + +GGTDNHL+LV+L+ G++G+R E VL+ HIA NK Sbjct: 352 YGEQVLKNAKTLAERMKKHGYALATGGTDNHLLLVDLRPIGVEGARAEHVLDLAHIACNK 411 Query: 1308 NTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKD 1487 NT PGDVSA+ PGGIR+GTPALTSRGF E+DF KV +F G LKD Sbjct: 412 NTCPGDVSALRPGGIRLGTPALTSRGFQEQDFEKVGDFIHE-GVQIAKKYNAEAGKTLKD 470 Query: 1488 FVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIGFE 1592 F + +++ + ++A L VEE++ +F G E Sbjct: 471 FKSFTETNEPFKKDVADLAKRVEEFSTKFEIPGNE 505
>O13972:GLYD_SCHPO Probable serine hydroxymethyltransferase, cytosolic -| Schizosaccharomyces pombe (Fission yeast) Length = 467 Score = 563 bits (1450), Expect = e-159 Identities = 280/453 (61%), Positives = 339/453 (74%), Gaps = 2/453 (0%) Frame = +3 Query: 225 PLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYG 404 PL+E DP +A+I+ E RQ + LI SENFTS +VM A+GSVM+NKYSEGYPGARYYG Sbjct: 11 PLKEQDPTVAEIMRHEADRQRSSVVLIASENFTSRAVMDALGSVMSNKYSEGYPGARYYG 70 Query: 405 GNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLP 584 GN++ID ETLCQ+RAL AFNLDP KWGVNVQ LSGSPAN VY A++ PH R+M LDLP Sbjct: 71 GNKFIDQIETLCQERALAAFNLDPAKWGVNVQCLSGSPANMQVYQAIMPPHGRLMGLDLP 130 Query: 585 HGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASA 764 GGHLSHGYQTDTKKISAVS +FE+MPYR+D +TGLIDYD LE A LFRPK++VAG SA Sbjct: 131 SGGHLSHGYQTDTKKISAVSTYFESMPYRVDPNTGLIDYDMLEHDAQLFRPKILVAGTSA 190 Query: 765 YARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRG 944 Y RL DY RMR+I D A L+ DMAHISGLV+AGVIPSPFEYADVVTTTTHKSLRGPRG Sbjct: 191 YCRLIDYARMRQIADSVNAYLVVDMAHISGLVSAGVIPSPFEYADVVTTTTHKSLRGPRG 250 Query: 945 AMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 AMIFFR+G+++ +K+G + YD EDKIN +VFPG QGGPHNHTIT LAVALKQ Y+ Sbjct: 251 AMIFFRRGLRKHDKKGNPIYYDLEDKINFSVFPGHQGGPHNHTITALAVALKQCQEPAYK 310 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAAN 1304 YQ QV+ N+ E +GY + + GTD+H+VLV++K KG+DG+R E+VLE ++I N Sbjct: 311 EYQAQVVKNAKVCEEEFKKRGYKLAADGTDSHMVLVDVKSKGVDGARAERVLELINIVTN 370 Query: 1305 KNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS--XXXXXXXXXXXXXGTK 1478 KNTVP D SA P GIR+GTPA+T+RGF E+DF +V ++ D K Sbjct: 371 KNTVPSDKSAFSPSGIRVGTPAMTTRGFKEQDFVRVVDYIDRALTFAANLQKELPKDANK 430 Query: 1479 LKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 LKDF A L + E+ +L+ +V E+A FP Sbjct: 431 LKDFKAKL-GEGEQYPELVQLQKEVAEWASSFP 462
>O13426:GLYC_CANAL Serine hydroxymethyltransferase, cytosolic - Candida albicans (Yeast)| Length = 470 Score = 561 bits (1445), Expect = e-159 Identities = 277/453 (61%), Positives = 341/453 (75%), Gaps = 3/453 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L++ DPE+ II+ E RQ + LI SENFT+ +V A+G+ M NKYSEGYPGARYYGG Sbjct: 18 LKDTDPEVDQIIKDEIDRQQHSIVLIASENFTTTAVFDALGTPMCNKYSEGYPGARYYGG 77 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 NE+I E LCQ+RAL+AF L P+KWGVNVQ LSGSPAN VY A++KPH+R+M LDLPH Sbjct: 78 NEHIHRMELLCQERALKAFGLTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLMGLDLPH 137 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHLSHGYQTD++KISAVS +FETMPYR+D TGLIDYD LEK+AVL+RPK++VAG SAY Sbjct: 138 GGHLSHGYQTDSRKISAVSTYFETMPYRVDLETGLIDYDMLEKTAVLYRPKVLVAGTSAY 197 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 RL DY RMR+I DK A L+ DMAHISGL+AAGVIPSPFEYAD+VTTTTHKSLRGPRGA Sbjct: 198 CRLIDYKRMREIADKVGAYLVVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGA 257 Query: 948 MIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 MIFFR+GV+ +N K G+E+ YD E+ IN +VFPG QGGPHNHTI LA ALKQA T E++ Sbjct: 258 MIFFRRGVRSVNPKTGQEILYDLENPINFSVFPGHQGGPHNHTIAALATALKQANTPEFK 317 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAAN 1304 YQEQV+ N+ T KGY +VS GTD+H+VLV+LK K IDG+RVE V E ++IA N Sbjct: 318 EYQEQVLKNAKALESEFTKKGYKLVSDGTDSHMVLVSLKDKQIDGARVETVCEKINIALN 377 Query: 1305 KNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD--SXXXXXXXXXXXXXGTK 1478 KN++PGD SA+VPGG+R+G PA+T+RG EEDF K+ + D K Sbjct: 378 KNSIPGDKSALVPGGVRIGAPAMTTRGLGEEDFKKIVSYIDFAVNYAKEVQSQLPKDANK 437 Query: 1479 LKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 LKDF + DS ++ +R ++ ++A FP Sbjct: 438 LKDFKNAVSGDSE---KLKAVRDEIYQWAGSFP 467
>P14519:GLYM_RABIT Serine hydroxymethyltransferase, mitochondrial precursor -| Oryctolagus cuniculus (Rabbit) Length = 504 Score = 558 bits (1437), Expect = e-158 Identities = 286/496 (57%), Positives = 359/496 (72%), Gaps = 9/496 (1%) Frame = +3 Query: 129 QPLSRLTPLYSMASLPATEERSAVT--------WPKQLNAPLEEVDPEIADIIELEKARQ 284 +PL R PL A + A ++A T W Q + L + DPE+ ++++ EK RQ Sbjct: 11 RPLQRCGPLVRTA-VRAQHGKAAQTQTGEASRGWTGQES--LSDTDPEMWELLQREKDRQ 67 Query: 285 WKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAF 464 +GLELI SENF + ++A+GS + NKYSEGYPG RYYGG E +D E LCQ+RALEAF Sbjct: 68 CRGLELIASENFCIRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAF 127 Query: 465 NLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVS 644 +LDP +WGVNVQP SGSPAN YTALL+PHDRIM LDLP GGHL+HGY +D K++SA S Sbjct: 128 DLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRVSATS 187 Query: 645 IFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAV 824 IFFE+MPY+L+ TGLIDY+QL +A LFRP+LI+AG SAYARL DY RMR++CD+ KA Sbjct: 188 IFFESMPYKLNPQTGLIDYEQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAH 247 Query: 825 LLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFRKGVKEIN-KQGKEV 1001 LLADMAHISGLVAA VIPSPF++ADVVTTTTHK+LRG R +IF+RKGV+ ++ K G+E+ Sbjct: 248 LLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGVRTVDPKTGQEI 307 Query: 1002 KYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQVMSNSARFAESLTS 1181 Y FED+IN AVFP LQGGPHNH I +AVALKQA T +R Y QV+ N+ A++L Sbjct: 308 PYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLE 367 Query: 1182 KGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVPGDVSAMVPGGIRMG 1361 +GY +VSGGTDNHLVLV+L+ KG+DG+R E+VLE V I ANKNT PGD SA+ PGG+R+G Sbjct: 368 RGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLG 427 Query: 1362 TPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFVATLQSDSNIQAEIAKL 1541 PALTSR F E+DF +V +F D KL+DF + L D +A L Sbjct: 428 APALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKT--AKLQDFKSFLLKDPETSQHLADL 485 Query: 1542 RHDVEEYAKQFPTIGF 1589 R V+++A+ FP GF Sbjct: 486 RRRVQQFARAFPMPGF 501
>Q7S5N8:GLYM_NEUCR Putative serine hydroxymethyltransferase, mitochondrial precursor -| Neurospora crassa Length = 527 Score = 556 bits (1433), Expect = e-157 Identities = 280/453 (61%), Positives = 342/453 (75%), Gaps = 17/453 (3%) Frame = +3 Query: 270 EKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMAETLCQKR 449 EK RQ + + LIPSENFTS +V+ A+GS M NKYSEGYPGARYYGGNE+ID +E LCQ R Sbjct: 69 EKQRQKQFINLIPSENFTSQAVLDALGSPMQNKYSEGYPGARYYGGNEFIDASERLCQDR 128 Query: 450 ALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHLSHGYQTDTKK 629 ALE F LDP++WGVNVQ LSG+PAN +VY+AL+ HDR+M LDLPHGGHLSHGYQT TKK Sbjct: 129 ALETFGLDPKEWGVNVQALSGAPANLYVYSALMDTHDRLMGLDLPHGGHLSHGYQTPTKK 188 Query: 630 ISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLYDYNRMRKICD 809 IS +S +FET+PYRLDE TG IDY++LE+ A+ +RPK+IVAGASAY+RL DY R+R+ICD Sbjct: 189 ISFISKYFETLPYRLDEKTGYIDYNKLEELAITYRPKIIVAGASAYSRLIDYARLREICD 248 Query: 810 KQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFRKGVKEINKQ 989 K A L+ADMAHISGLVAA V+P PF +AD+VTTT+HKSLRGPRGAMIFFR+GV+ NK+ Sbjct: 249 KVNAYLMADMAHISGLVAAKVMPGPFTHADIVTTTSHKSLRGPRGAMIFFRRGVRRTNKK 308 Query: 990 GKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQVMSNSARFAE 1169 G+E Y+ E INA+VFPG QGGPHNHTI LAVALKQA T E+RAYQ QV++N+ A Sbjct: 309 GEEELYNLETPINASVFPGHQGGPHNHTIAALAVALKQAQTPEFRAYQSQVLANATALAA 368 Query: 1170 SL------TSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVPGDVS 1331 L GY IVSGGTDNHLVL++LK +GIDGSRVE+VLE V +AANKNTVPGD S Sbjct: 369 RLGEPKDKNGLGYTIVSGGTDNHLVLIDLKPQGIDGSRVERVLELVGVAANKNTVPGDKS 428 Query: 1332 AMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD-----------SXXXXXXXXXXXXXGTK 1478 A+ PGG+R+GTPA+T+RGF EEDFA+VA+ D + + Sbjct: 429 ALTPGGLRIGTPAMTTRGFTEEDFARVADIIDRAVTIAVRINKAAKEDAVKKGNEKAANR 488 Query: 1479 LKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 +K F+ L + EI +LR +VE + +P Sbjct: 489 VKTFMDYL-GNGETDPEIVQLRSEVESWVGTYP 520
>P50431:GLYC_MOUSE Serine hydroxymethyltransferase, cytosolic - Mus musculus (Mouse)| Length = 478 Score = 551 bits (1421), Expect = e-156 Identities = 280/472 (59%), Positives = 342/472 (72%), Gaps = 5/472 (1%) Frame = +3 Query: 186 ERSAVTWP---KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSV 356 +R A W K L+ PL++ D E+ II+ E RQ GLELI SENF S +V++A+GS Sbjct: 3 DRDATLWASHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGSS 62 Query: 357 MTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVY 536 + NKYSEGYPG RYYGG E+ID E LCQKRAL+A++LDP+ WGVNVQP SGSPANF VY Sbjct: 63 LNNKYSEGYPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAVY 122 Query: 537 TALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEK 716 TAL++PH RIM LDLP GGHL+HG+ TD KKISA SIFFE+MPY++ TG I+YDQLE+ Sbjct: 123 TALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQLEE 182 Query: 717 SAVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYA 896 +A LF PKLI+AG S Y+R DY R+RKI D A L+ADMAHISGLVAAGV+PSPFE+ Sbjct: 183 NASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHC 242 Query: 897 DVVTTTTHKSLRGPRGAMIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHT 1073 VVTTTTHK+LRG R MIF+RKGV+ ++ K GKE Y+ E IN+AVFPGLQGGPHNH Sbjct: 243 HVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHNHA 302 Query: 1074 ITGLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGI 1253 I G+AVALKQA T E++ YQ QV++N +++LT GY IV+GG+DNHL+L++L+ KG Sbjct: 303 IAGVAVALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKGT 362 Query: 1254 DGSRVEKVLENVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD-S 1430 DG R EKVLE IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF KVA F Sbjct: 363 DGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRG 422 Query: 1431 XXXXXXXXXXXXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 LK+F L D IQ+ +A LR +VE +A F G Sbjct: 423 IELTLQIQSHMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPG 474
>P34896:GLYC_HUMAN Serine hydroxymethyltransferase, cytosolic - Homo sapiens (Human)| Length = 483 Score = 549 bits (1414), Expect = e-155 Identities = 279/461 (60%), Positives = 340/461 (73%), Gaps = 2/461 (0%) Frame = +3 Query: 210 KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPG 389 K L PL++ D E+ +II+ E RQ GLELI SENF S +V++A+GS + NKYSEGYPG Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79 Query: 390 ARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIM 569 RYYGG E+ID ETLCQKRAL+A+ LDP+ WGVNVQP SGSPANF VYTAL++PH RIM Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139 Query: 570 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIV 749 LDLP GGHL+HG+ TD KKISA SIFFE+MPY+++ TG I+YDQLE++A LF PKLI+ Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199 Query: 750 AGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSL 929 AG S Y+R +Y R+RKI D+ A L+ADMAHISGLVAAGV+PSPFE+ VVTTTTHK+L Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259 Query: 930 RGPRGAMIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQA 1106 RG R MIF+RKGVK ++ K GKE+ Y+ E IN+AVFPGLQGGPHNH I G+AVALKQA Sbjct: 260 RGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQA 319 Query: 1107 TTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLEN 1286 T E++ YQ QV++N +E+LT GY IV+GG+DNHL+LV+L+ KG DG R EKVLE Sbjct: 320 MTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEA 379 Query: 1287 VHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD-SXXXXXXXXXXX 1463 IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA F Sbjct: 380 CSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDT 439 Query: 1464 XXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 LK+F L D QA + LR +VE +A FP G Sbjct: 440 GVRATLKEFKERLAGD-KYQAAVQALREEVESFASLFPLPG 479
>Q6FUP6:GLYC_CANGA Serine hydroxymethyltransferase, cytosolic - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 469 Score = 547 bits (1409), Expect = e-155 Identities = 266/459 (57%), Positives = 342/459 (74%), Gaps = 3/459 (0%) Frame = +3 Query: 210 KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPG 389 K ++ L E DPE+ II+ E RQ ++LI SENFT+ SV A+G+ + NKYSEGYPG Sbjct: 11 KMVSGHLSETDPEVEQIIKDEVDRQKHSIDLIASENFTTTSVFDALGTPLCNKYSEGYPG 70 Query: 390 ARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIM 569 ARYYGGNE+ID E LCQ+RALEAF++ P++WGVNVQ LSGSPAN VY AL+KPH+R+M Sbjct: 71 ARYYGGNEHIDRIERLCQQRALEAFHVTPDRWGVNVQTLSGSPANLQVYQALMKPHERLM 130 Query: 570 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIV 749 L LP GGHLSHGY T+ +KISAVS +FE+ PYR++ TG+IDYD LEK+A+L+RPK++V Sbjct: 131 GLYLPDGGHLSHGYATENRKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILYRPKILV 190 Query: 750 AGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSL 929 AG SAY RL DY RMR+I DK A L+ DMAHISGLVAAGVIPSPFEYAD+VTTTTHKSL Sbjct: 191 AGTSAYCRLIDYKRMREIADKCGAYLMVDMAHISGLVAAGVIPSPFEYADIVTTTTHKSL 250 Query: 930 RGPRGAMIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQA 1106 RGPRGAMIFFR+G++ +N K GKE+ YD E+ IN +VFPG QGGPHNHTI LA ALKQA Sbjct: 251 RGPRGAMIFFRRGIRSVNQKTGKEIPYDLENPINFSVFPGHQGGPHNHTIAALATALKQA 310 Query: 1107 TTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLEN 1286 T E++ YQ QV+ N+ + GY +VS GTD+H+VLV+L++KG+DG+RVE V E Sbjct: 311 ATPEFKEYQTQVLKNAKALENEFQTLGYRLVSNGTDSHMVLVSLREKGVDGARVEYVCEK 370 Query: 1287 VHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS--XXXXXXXXXX 1460 ++IA NKN++PGD SA+VPGG+R+G PA+T+RG EEDF ++ + D Sbjct: 371 INIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVRYIDQAVKFAEQTQSSL 430 Query: 1461 XXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 KLKDF A + I ++A L+ ++ ++ ++P Sbjct: 431 PKEANKLKDFKAKV---DEIADQLAPLKKEIYDWTAEYP 466
>P35623:GLYC_SHEEP Serine hydroxymethyltransferase, cytosolic - Ovis aries (Sheep)| Length = 484 Score = 546 bits (1408), Expect = e-155 Identities = 281/472 (59%), Positives = 341/472 (72%), Gaps = 6/472 (1%) Frame = +3 Query: 189 RSAVTWP---KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVM 359 R A W K L PL++ D E+ +II+ E RQ GLELI SENF S +V++A+GS + Sbjct: 10 RDADLWSLHEKMLAQPLKDNDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCL 69 Query: 360 TNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYT 539 NKYSEGYPG RYYGG E+ID E LCQKRAL+ + LDPE WGVNVQP SGSPANF VYT Sbjct: 70 NNKYSEGYPGQRYYGGTEFIDELEVLCQKRALQVYGLDPECWGVNVQPYSGSPANFAVYT 129 Query: 540 ALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKS 719 AL++PH RIM LDLP GGHL+HG+ TD KKISA SIFFE+MPY+++ TG I+YDQLE++ Sbjct: 130 ALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEEN 189 Query: 720 AVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYAD 899 A LF P+LI+AG S Y+R DY R+RKI D A L+ADMAHISGLVAAGV+PSPFE+ Sbjct: 190 ARLFHPRLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHCH 249 Query: 900 VVTTTTHKSLRGPRGAMIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHTI 1076 VV+TTTHK+LRG R MIF+RKGV+ ++ K GKE +Y+ E IN+AVFPGLQGGPHNH I Sbjct: 250 VVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETRYNLESLINSAVFPGLQGGPHNHAI 309 Query: 1077 TGLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGID 1256 G+AVALKQA T E+RAYQ QV++N AE+L GY +V+GG+DNHL+LV+L+ KG D Sbjct: 310 AGVAVALKQAMTPEFRAYQRQVVANCRALAEALMGLGYRVVTGGSDNHLILVDLRSKGTD 369 Query: 1257 GSRVEKVLENVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXX 1436 G R EKVLE IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF KVA F Sbjct: 370 GGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFRKVAHFI-HRG 428 Query: 1437 XXXXXXXXXXXGTK--LKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 G K LK+F+ L Q + LR +VE +A FP G Sbjct: 429 IELTLQIQDAVGVKATLKEFMEKLAGAEEHQRAVTALRAEVESFATLFPLPG 480
>Q75BQ6:GLYC_ASHGO Serine hydroxymethyltransferase, cytosolic - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 469 Score = 545 bits (1405), Expect = e-154 Identities = 270/459 (58%), Positives = 345/459 (75%), Gaps = 3/459 (0%) Frame = +3 Query: 210 KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPG 389 K +++ L E DPE+ II+ E RQ + LI SEN TS +V A+G+ M NKYSEGYPG Sbjct: 11 KLISSHLSESDPEVDAIIKDEIDRQKHSIVLIASENLTSTAVFDALGTPMCNKYSEGYPG 70 Query: 390 ARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIM 569 ARYYGGN++ID E LCQ+RALEAF++ P++WGVNVQ LSGSPAN VY AL+KPH+R+M Sbjct: 71 ARYYGGNQHIDRMELLCQRRALEAFHVTPDRWGVNVQSLSGSPANLQVYQALMKPHERLM 130 Query: 570 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIV 749 L LP GGHLSHGYQT+T+KISAVS +FE+ PYR+D TG+IDYD LEK+AVL+RPK++V Sbjct: 131 GLHLPDGGHLSHGYQTETRKISAVSTYFESFPYRVDPETGIIDYDTLEKNAVLYRPKILV 190 Query: 750 AGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSL 929 AG SAY RL DY RMR+I DK A L+ DMAHISGLVAAGVIPSPFEYAD+VTTTTHKSL Sbjct: 191 AGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLVAAGVIPSPFEYADIVTTTTHKSL 250 Query: 930 RGPRGAMIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQA 1106 RGPRGAMIFFR+GV+ ++ K G+EV YD E IN +VFPG QGGPHNHTI+ LA ALKQA Sbjct: 251 RGPRGAMIFFRRGVRSVHPKTGEEVMYDLEGPINFSVFPGHQGGPHNHTISALATALKQA 310 Query: 1107 TTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLEN 1286 TT E+R YQE V+ N+ Y +VS GTD+H+VLV+L++KG+DG+RVE V E Sbjct: 311 TTPEFREYQELVLKNAKVLETEFKKLNYRLVSDGTDSHMVLVSLREKGVDGARVEHVCEK 370 Query: 1287 VHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS--XXXXXXXXXX 1460 ++IA NKN++PGD SA+VPGG+R+G PA+T+RG EEDFA++ + + Sbjct: 371 INIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFARIVGYINRAVEIARSIQQSL 430 Query: 1461 XXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 +LKDF A ++ ++ EIA+L ++ + +++P Sbjct: 431 PKEANRLKDFKAKVEGGTD---EIAQLAQEIYSWTEEYP 466
>P07511:GLYC_RABIT Serine hydroxymethyltransferase, cytosolic - Oryctolagus cuniculus| (Rabbit) Length = 484 Score = 545 bits (1403), Expect = e-154 Identities = 278/480 (57%), Positives = 341/480 (71%), Gaps = 5/480 (1%) Frame = +3 Query: 162 MASLPATEERSAVTWP---KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLS 332 MA+ R A W + L PL++ D E+ DII+ E RQ GLELI SENF S + Sbjct: 1 MATAVNGAPRDAALWSSHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRA 60 Query: 333 VMQAVGSVMTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSG 512 V++A+GS + NKYSEGYPG RYYGG E+ID ETLCQKRAL+A+ LDP+ WGVNVQP SG Sbjct: 61 VLEALGSCLNNKYSEGYPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSG 120 Query: 513 SPANFHVYTALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGL 692 SPANF VYTAL++PH RIM LDLP GGHL+HG+ TD KKISA SIFFE+M Y+++ TG Sbjct: 121 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGY 180 Query: 693 IDYDQLEKSAVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGV 872 IDYD+LE++A LF PKLI+AG S Y+R DY R+RKI D+ A L+ADMAHISGLV AGV Sbjct: 181 IDYDRLEENARLFHPKLIIAGTSCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGV 240 Query: 873 IPSPFEYADVVTTTTHKSLRGPRGAMIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGL 1049 +PSPFE+ VVTTTTHK+LRG R MIF+R+GV+ ++ K GKE+ Y+ E IN+AVFPGL Sbjct: 241 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGL 300 Query: 1050 QGGPHNHTITGLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVL 1229 QGGPHNH I G+AVALKQA T E++ YQ QV++N + +L GY IV+GG+DNHL+L Sbjct: 301 QGGPHNHAIAGVAVALKQAMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLIL 360 Query: 1230 VNLKKKGIDGSRVEKVLENVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAK 1409 V+L+ KG DG R EKVLE IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF K Sbjct: 361 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQK 420 Query: 1410 VAEFFD-SXXXXXXXXXXXXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 VA F LK+F L D Q + LR +VE +A FP G Sbjct: 421 VAHFIHRGIELTVQIQDDTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPG 480
>Q6CLQ5:GLYM_KLULA Serine hydroxymethyltransferase, mitochondrial precursor -| Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 498 Score = 544 bits (1401), Expect = e-154 Identities = 256/401 (63%), Positives = 328/401 (81%), Gaps = 1/401 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++++DPE+ DI+ E+ RQ + LIPSENFTS SVM +GS M NKYSEGYPG RYYGG Sbjct: 41 VQDIDPEMYDILTKERKRQKHSITLIPSENFTSKSVMDLLGSEMQNKYSEGYPGERYYGG 100 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 N++IDMAE+LCQKRALE +NLDP+ WGVNVQPLSG+PAN + Y+A+++ +DR+M LDLPH Sbjct: 101 NQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSGAPANLYAYSAVMETNDRLMGLDLPH 160 Query: 588 GGHLSHGYQTDT-KKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASA 764 GGHLSHGYQ + KIS +S +F+TMPY +D TG+IDYD L K++ LFRPK+IVAGASA Sbjct: 161 GGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTGIIDYDFLSKTSKLFRPKVIVAGASA 220 Query: 765 YARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRG 944 Y+R+ DY R ++I D A L++DMAHISGLVAAGV SPFEY+D+VTTTTHKSLRGPRG Sbjct: 221 YSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAGVTRSPFEYSDIVTTTTHKSLRGPRG 280 Query: 945 AMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 AMIF+RKGV+++ K+GKEV YD + +IN +VFPG QGGPHNHTI+ LAVALKQA T E++ Sbjct: 281 AMIFYRKGVRKVTKKGKEVLYDLDKRINFSVFPGHQGGPHNHTISALAVALKQAATPEFK 340 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAAN 1304 YQ V+ N+ F E L KG+++VSGGTD HL+L+NL GIDG+R+E +LEN++IAAN Sbjct: 341 EYQAAVVENARIFGEELVKKGFELVSGGTDTHLILINLSNLGIDGARLETLLENINIAAN 400 Query: 1305 KNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 KNT+PGD SA+ P G+R+GTPA+T+RGF ++FA+VA + D Sbjct: 401 KNTIPGDKSALFPSGLRVGTPAMTTRGFGPQEFAQVAAYID 441
>Q5RFK5:GLYC_PONPY Serine hydroxymethyltransferase, cytosolic - Pongo pygmaeus| (Orangutan) Length = 483 Score = 542 bits (1396), Expect = e-153 Identities = 276/461 (59%), Positives = 336/461 (72%), Gaps = 2/461 (0%) Frame = +3 Query: 210 KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPG 389 K L PL++ D E+ +II+ E RQ GLEL SENF S +V++A+GS + NKYSEGYPG Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELFASENFASQAVLEALGSCLNNKYSEGYPG 79 Query: 390 ARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIM 569 RYYGG E+ID ETLCQKRAL+A+ LDP+ WGVNVQP SGSPANF VYTAL++PH RIM Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139 Query: 570 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIV 749 LDLP GGHL+HG+ T KKISA SIFFE+MPY+++ TG I+YDQLE++A LF PKLI+ Sbjct: 140 GLDLPDGGHLTHGFMTGKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199 Query: 750 AGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSL 929 AG S Y+R DY R+RKI D+ A L+ADMAHISGLVAAGV+PSPFE+ VVTTTTHK+L Sbjct: 200 AGTSCYSRNLDYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259 Query: 930 RGPRGAMIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQA 1106 RG R MIF+RKGV+ ++ K GKE+ Y+ E IN+AVFPGLQGGPHNH I G+AVALKQA Sbjct: 260 RGCRAGMIFYRKGVQSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQA 319 Query: 1107 TTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLEN 1286 T E++ YQ QV++N +E+LT GY IV+GG+DNHL+LV+L+ KG DG R EKVLE Sbjct: 320 MTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEA 379 Query: 1287 VHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD-SXXXXXXXXXXX 1463 IA NKNT PGD SA+ P G+R+GTPALTSRG +E+DF KVA F Sbjct: 380 CSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDT 439 Query: 1464 XXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 LK+F L D Q + LR VE +A FP G Sbjct: 440 GVRATLKEFKERLAGD-KYQGAVQALREKVESFASLFPLPG 479
>Q5E9P9:GLYC_BOVIN Serine hydroxymethyltransferase, cytosolic - Bos taurus (Bovine)| Length = 484 Score = 540 bits (1392), Expect = e-153 Identities = 277/472 (58%), Positives = 340/472 (72%), Gaps = 6/472 (1%) Frame = +3 Query: 189 RSAVTWP---KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVM 359 R A W K L PL++ D E+ +II+ E RQ GLELI SENF S +V++A+GS + Sbjct: 10 RDANLWSLHEKMLAQPLKDNDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCL 69 Query: 360 TNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYT 539 NKYSEGYPG RYYGG E+ID E LCQKRAL+ + LD + WGVNVQP SGSPANF VYT Sbjct: 70 NNKYSEGYPGQRYYGGTEFIDELEVLCQKRALQVYGLDSQCWGVNVQPYSGSPANFAVYT 129 Query: 540 ALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKS 719 AL++PH RIM LDLP GGHL+HG+ TD KKISA SIFFE+MPY+++ TG I+YDQLE++ Sbjct: 130 ALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEEN 189 Query: 720 AVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYAD 899 A LF P+LI+AG S Y+R DY R+RKI D A L+ADMAH+SGLVAAGV+PSPFE+ Sbjct: 190 ARLFHPRLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHVSGLVAAGVVPSPFEHCH 249 Query: 900 VVTTTTHKSLRGPRGAMIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHTI 1076 VV+TTTHK+LRG R MIF+RKGV+ ++ K G+E +Y+ E IN+AVFPGLQGGPHNH I Sbjct: 250 VVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGRETRYNLESLINSAVFPGLQGGPHNHAI 309 Query: 1077 TGLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGID 1256 G+AVALKQA T E+RAYQ QV++N AE+L GY +V+GG+DNHL+LV+L+ KG D Sbjct: 310 AGVAVALKQAMTPEFRAYQRQVVANCRALAEALMGLGYRVVTGGSDNHLILVDLRSKGTD 369 Query: 1257 GSRVEKVLENVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXX 1436 G R EKVLE IA NKNT PGD SA+ P G+R+GTPALTSRG +EEDF KVA F Sbjct: 370 GGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFI-HRG 428 Query: 1437 XXXXXXXXXXXGTK--LKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 G K LK+F+ L +A LR +VE +A FP G Sbjct: 429 IELTLQIQDAVGVKATLKEFMEKLAGAEEHHRAVAALRAEVESFATLFPLPG 480
>P37291:GLYC_YEAST Serine hydroxymethyltransferase, cytosolic - Saccharomyces cerevisiae| (Baker's yeast) Length = 469 Score = 540 bits (1391), Expect = e-153 Identities = 263/459 (57%), Positives = 344/459 (74%), Gaps = 3/459 (0%) Frame = +3 Query: 210 KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPG 389 K + + L + DPE+ II+ E RQ ++LI SENFTS SV A+G+ ++NKYSEGYPG Sbjct: 11 KLITSHLVDTDPEVDSIIKDEIERQKHSIDLIASENFTSTSVFDALGTPLSNKYSEGYPG 70 Query: 390 ARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIM 569 ARYYGGNE+ID E LCQ+RAL+AF++ P+KWGVNVQ LSGSPAN VY A++KPH+R+M Sbjct: 71 ARYYGGNEHIDRMEILCQQRALKAFHVTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLM 130 Query: 570 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIV 749 L LP GGHLSHGY T+ +KISAVS +FE+ PYR++ TG+IDYD LEK+A+L+RPK++V Sbjct: 131 GLYLPDGGHLSHGYATENRKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILYRPKVLV 190 Query: 750 AGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSL 929 AG SAY RL DY RMR+I DK A L+ DMAHISGL+AAGVIPSPFEYAD+VTTTTHKSL Sbjct: 191 AGTSAYCRLIDYKRMREIADKCGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSL 250 Query: 930 RGPRGAMIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQA 1106 RGPRGAMIFFR+GV+ IN K GKEV YD E+ IN +VFPG QGGPHNHTI LA ALKQA Sbjct: 251 RGPRGAMIFFRRGVRSINPKTGKEVLYDLENPINFSVFPGHQGGPHNHTIAALATALKQA 310 Query: 1107 TTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLEN 1286 T E++ YQ QV+ N+ + GY +VS GTD+H+VLV+L++KG+DG+RVE + E Sbjct: 311 ATPEFKEYQTQVLKNAKALESEFKNLGYRLVSNGTDSHMVLVSLREKGVDGARVEYICEK 370 Query: 1287 VHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS--XXXXXXXXXX 1460 ++IA NKN++PGD SA+VPGG+R+G PA+T+RG EEDF ++ ++ + Sbjct: 371 INIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVQYINKAVEFAQQVQQSL 430 Query: 1461 XXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 +LKDF A + S++ + + ++ ++A ++P Sbjct: 431 PKDACRLKDFKAKVDEGSDV---LNTWKKEIYDWAGEYP 466
>P34898:GLYC_NEUCR Serine hydroxymethyltransferase, cytosolic - Neurospora crassa| Length = 480 Score = 537 bits (1383), Expect = e-152 Identities = 276/462 (59%), Positives = 341/462 (73%), Gaps = 3/462 (0%) Frame = +3 Query: 201 TWPKQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEG 380 T L L E DP++A+I++ E RQ + + LI SEN TS +V A+GS M+NKYSEG Sbjct: 9 THKAMLEHSLVESDPQVAEIMKKEVQRQRESIILIASENVTSRAVFDALGSPMSNKYSEG 68 Query: 381 YPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHD 560 PGARYYGGN++ID E LCQ RALEAF+LDP++WGVNVQ LSGSPAN VY A++ H Sbjct: 69 LPGARYYGGNQHIDEIEVLCQNRALEAFHLDPKQWGVNVQCLSGSPANLQVYQAIMPVHG 128 Query: 561 RIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPK 740 R+M LDLPHGGHLSHGYQT +KISAVS +FETMPYR++ TGLIDYD LEK+A LFRPK Sbjct: 129 RLMGLDLPHGGHLSHGYQTPQRKISAVSTYFETMPYRVNIDTGLIDYDTLEKNAQLFRPK 188 Query: 741 LIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTH 920 ++VAG SAY RL DY RMRKI D A L+ DMAHISGL+A+ VIPSPF YADVVTTTTH Sbjct: 189 VLVAGTSAYCRLIDYERMRKIADSVGAYLVVDMAHISGLIASEVIPSPFLYADVVTTTTH 248 Query: 921 KSLRGPRGAMIFFRKGVKEIN-KQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVAL 1097 KSLRGPRGAMIFFR+GV+ ++ K GKE YD EDKIN +VFPG QGGPHNHTIT LAVAL Sbjct: 249 KSLRGPRGAMIFFRRGVRSVDAKTGKETLYDLEDKINFSVFPGHQGGPHNHTITALAVAL 308 Query: 1098 KQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKV 1277 KQA + E++ YQ++V++N+ + L GY +VS GTD+H+VLV+L+ G+DG+RVE + Sbjct: 309 KQAASPEFKEYQQKVVANAKALEKKLKELGYKLVSDGTDSHMVLVDLRPIGVDGARVEFL 368 Query: 1278 LENVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS--XXXXXXX 1451 LE ++I NKN VPGD SA+ PGG+R+GTPA+TSRGF E DF KVA F D Sbjct: 369 LEQINITCNKNAVPGDKSALTPGGLRIGTPAMTSRGFGEADFEKVAVFVDEAVKLCKEIQ 428 Query: 1452 XXXXXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 K KDF A + + S+I I +L+ ++ ++ FP Sbjct: 429 ASLPKEANKQKDFKAKI-ATSDI-PRINELKQEIAAWSNTFP 468
>Q758F0:GLYM_ASHGO Serine hydroxymethyltransferase, mitochondrial precursor - Ashbya| gossypii (Yeast) (Eremothecium gossypii) Length = 497 Score = 535 bits (1378), Expect = e-151 Identities = 266/485 (54%), Positives = 352/485 (72%), Gaps = 3/485 (0%) Frame = +3 Query: 141 RLTPLYSMASLPATEERSAVTWPKQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENF 320 RLT ++ + T RSA L+ ++E DPE+ DI+ E++RQ + + LIPSENF Sbjct: 12 RLTCGEALRACQQTGARSA-NGQLMLSQHVQEFDPEMYDILTKERSRQKRSITLIPSENF 70 Query: 321 TSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQ 500 TS++VM +GS M NKYSEGYPG RYYGGN+YIDMAE+LCQKRALE + LDP KWGVNVQ Sbjct: 71 TSVAVMNLLGSEMQNKYSEGYPGQRYYGGNQYIDMAESLCQKRALELYGLDPAKWGVNVQ 130 Query: 501 PLSGSPANFHVYTALLKPHDRIMALDLPHGGHLSHGYQTDT-KKISAVSIFFETMPYRLD 677 LSG+PAN + Y+A+++ DR+M LDLPHGGHLSHGYQ KIS +S +F+TM YR+D Sbjct: 131 SLSGAPANLYAYSAIMEVGDRMMGLDLPHGGHLSHGYQLQNGNKISYISKYFQTMAYRVD 190 Query: 678 ESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGL 857 +TGL+DYD L +++ LFRPK+IVAG SAYAR+ DY R R+I D A LL+DMAH+SGL Sbjct: 191 PATGLVDYDTLSETSKLFRPKVIVAGTSAYARVLDYKRFREIADACGAYLLSDMAHVSGL 250 Query: 858 VAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAV 1037 VAAGV PSPFEY+D+VTTTTHKSLRGPRGAMIF+RKG++++ K+G E+ YD + +IN +V Sbjct: 251 VAAGVHPSPFEYSDIVTTTTHKSLRGPRGAMIFYRKGIRKVTKKGTEIMYDLDKRINFSV 310 Query: 1038 FPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDN 1217 FP QGGPHNHTI+ LAVALKQA T E++ YQ V+ N+ F E L+ +G+ +VSGGTD Sbjct: 311 FPAHQGGPHNHTISALAVALKQAATPEFKNYQTAVVENAKVFGEELSKRGFSLVSGGTDT 370 Query: 1218 HLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEE 1397 HL+L++L GIDGSR+E +LE ++IAANKNT+PGD SA+ P G+R+GTPA+T+RGF Sbjct: 371 HLLLIDLSPMGIDGSRLETILERLNIAANKNTIPGDKSALYPSGLRVGTPAMTTRGFGPA 430 Query: 1398 DFAKVAEFFDS--XXXXXXXXXXXXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQ 1571 +F +VA + + K +A +S ++ KL ++V ++ Q Sbjct: 431 EFGRVAAYINEAVKLAIGLKSQEPVDAKDAKTRLAHFKSFCAESEQVTKLANEVADWVAQ 490 Query: 1572 FPTIG 1586 +P G Sbjct: 491 YPVPG 495
>Q6FQ44:GLYM_CANGA Serine hydroxymethyltransferase, mitochondrial precursor - Candida| glabrata (Yeast) (Torulopsis glabrata) Length = 485 Score = 528 bits (1359), Expect = e-149 Identities = 266/458 (58%), Positives = 341/458 (74%), Gaps = 5/458 (1%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++EVDPE+ I+ E++RQ + LIPSENFTS +VM +GS M NKYSEGYPG RYYGG Sbjct: 27 VQEVDPEMFRILSDERSRQKHSVTLIPSENFTSKAVMDLLGSEMQNKYSEGYPGERYYGG 86 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 N++ID AE+LCQ RAL+ + LDPEKWGVNVQ LSG+PAN + Y+A+++ DR+M LDLPH Sbjct: 87 NQFIDKAESLCQARALDLYGLDPEKWGVNVQALSGAPANLYAYSAVMEVGDRLMGLDLPH 146 Query: 588 GGHLSHGYQTDT-KKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASA 764 GGHLSHGYQ + KIS +S +F TMPY ++ TG+IDYD L ++ LFRPK+IVAG SA Sbjct: 147 GGHLSHGYQLPSGTKISYISKYFNTMPYHVNTETGIIDYDTLAMTSKLFRPKVIVAGTSA 206 Query: 765 YARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRG 944 Y+R DY R RKI D A LL+DMAHISGLVAA VI SPFE++D+VTTTTHKSLRGPRG Sbjct: 207 YSRKLDYARFRKIADGCGAYLLSDMAHISGLVAANVIDSPFEHSDIVTTTTHKSLRGPRG 266 Query: 945 AMIFFRKGVKEINKQ-GKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEY 1121 AMIF+RKG+K++NK+ GKE + F+ IN +VFPG QGGPHNHTI+ LAVALKQA T E+ Sbjct: 267 AMIFYRKGIKKVNKKTGKETPFTFDKTINFSVFPGHQGGPHNHTISALAVALKQAKTPEF 326 Query: 1122 RAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAA 1301 YQ+QV+SN+ F + L +G+++VSGGTDNHL+L+NL GIDG+R+E +LE ++IAA Sbjct: 327 VEYQKQVVSNAKAFGDELLKRGFELVSGGTDNHLLLLNLSNMGIDGARLEAILEKINIAA 386 Query: 1302 NKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKL 1481 NKNT+PGD SA+ P G+R+GTPA+T+RGF E+DF KVAE+ D+ Sbjct: 387 NKNTIPGDKSALFPSGLRVGTPAMTTRGFQEQDFKKVAEYIDN-AVKLSIALKSQESADA 445 Query: 1482 KDFVATLQSDSNI--QAE-IAKLRHDVEEYAKQFPTIG 1586 KD + L S + Q+E + KL +V + FP G Sbjct: 446 KDVRSKLNSFKQLCDQSEPVQKLAEEVSSWVGTFPVPG 483
>P37292:GLYM_YEAST Serine hydroxymethyltransferase, mitochondrial precursor -| Saccharomyces cerevisiae (Baker's yeast) Length = 490 Score = 526 bits (1354), Expect = e-148 Identities = 256/460 (55%), Positives = 341/460 (74%), Gaps = 3/460 (0%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 ++ P+ E DPE+ DI++ E+ RQ + LIPSENFTS +VM +GS + NKYSEGYPG R Sbjct: 29 VSKPVSEGDPEMFDILQQERHRQKHSITLIPSENFTSKAVMDLLGSELQNKYSEGYPGER 88 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 YYGGNE ID +E+LCQ RALE + LDP KWGVNVQPLSG+PAN +VY+A++ +R+M L Sbjct: 89 YYGGNEIIDKSESLCQARALELYGLDPAKWGVNVQPLSGAPANLYVYSAIMNVGERLMGL 148 Query: 576 DLPHGGHLSHGYQTDT-KKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVA 752 DLP GGHLSHGYQ + IS +S +F++MPY +D +TGLIDYD L+ A FRPK+IVA Sbjct: 149 DLPDGGHLSHGYQLKSGTPISFISKYFQSMPYHVDHTTGLIDYDNLQVLAKAFRPKVIVA 208 Query: 753 GASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLR 932 G SAY+RL DY R ++I A L++DMAHISGLVAA V+PSPFE++D+VTTTTHKSLR Sbjct: 209 GTSAYSRLIDYARFKEISQGCGAYLMSDMAHISGLVAANVVPSPFEHSDIVTTTTHKSLR 268 Query: 933 GPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATT 1112 GPRGAMIFFRKG+K + K+GKE+ Y+ E KIN +VFPG QGGPHNHTI +AVALKQA + Sbjct: 269 GPRGAMIFFRKGIKSVTKKGKEIPYELEKKINFSVFPGHQGGPHNHTIGAMAVALKQAMS 328 Query: 1113 QEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVH 1292 E++ YQ++++ NS FA+ LT GY +VSGGTDNHL++++L +DG+RVE +L ++ Sbjct: 329 PEFKEYQQKIVDNSKWFAQELTKMGYKLVSGGTDNHLIVIDLSGTQVDGARVETILSALN 388 Query: 1293 IAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXG 1472 IAANKNT+PGD SA+ P G+R+GTPA+T+RGF E+F++VA++ DS Sbjct: 389 IAANKNTIPGDKSALFPSGLRIGTPAMTTRGFGREEFSQVAKYIDSAVKLAENLKTLEPT 448 Query: 1473 TKL--KDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 TKL + + + N +E+A L ++ ++ Q+P G Sbjct: 449 TKLDARSRLNEFKKLCNESSEVAALSGEISKWVGQYPVPG 488
>O62585:GLYC_ENCCU Serine hydroxymethyltransferase, cytosolic - Encephalitozoon cuniculi| Length = 460 Score = 416 bits (1068), Expect = e-115 Identities = 214/413 (51%), Positives = 283/413 (68%) Frame = +3 Query: 180 TEERSAVTWPKQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVM 359 T+ R W PLE DPE+ +I E RQ K + LI SEN+ S M+A GSV+ Sbjct: 2 TDAREKGFW----TGPLEMADPELHALICGEVERQKKTINLIASENYAHQSAMEACGSVL 57 Query: 360 TNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYT 539 TNKYSEG G RYYGG ++D E LCQKRALE F LDP+ WGVNVQP SGSPANF +YT Sbjct: 58 TNKYSEGRVGERYYGGTHWVDRIELLCQKRALELFGLDPDVWGVNVQPYSGSPANFAIYT 117 Query: 540 ALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKS 719 A++ P RIM LDLP GGHL+HGY+T T+KISA S++F++ PY + S GLIDY+ LEK+ Sbjct: 118 AVVPPGGRIMGLDLPSGGHLTHGYKTKTRKISASSVYFDSRPYTVG-SNGLIDYEGLEKT 176 Query: 720 AVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYAD 899 F P +++ G SAY+R DY R++ I + A L AD++HIS LVA+G++ SPFE+ D Sbjct: 177 FTDFLPHILICGYSAYSRDIDYKRLQSIAGRNGAFLFADISHISPLVASGLMNSPFEHCD 236 Query: 900 VVTTTTHKSLRGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTIT 1079 +V TTT K LRGPRGA+IF+R+ V K G+ V D + +IN AVFP LQGGPHNHTI Sbjct: 237 IVMTTTQKGLRGPRGALIFYRRAV---TKNGETV--DLDARINFAVFPMLQGGPHNHTIA 291 Query: 1080 GLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDG 1259 G+A AL A T E+ Y +V+ NS L S G DI++GGTDNH++LV+L+ G+DG Sbjct: 292 GIASALLHAGTPEFAEYTRRVVENSRELCSRLQSLGLDILTGGTDNHMLLVDLRSTGVDG 351 Query: 1260 SRVEKVLENVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 + VE + + + I+ N+N + G+ S + P GIR+GT A+T+RGF E+ +V + Sbjct: 352 AAVEHMCDALGISLNRNAIVGNSSPLSPSGIRVGTYAVTARGFGPEEMREVGD 404
>Q5WYH4:GLYA_LEGPL Serine hydroxymethyltransferase - Legionella pneumophila (strain| Lens) Length = 417 Score = 365 bits (937), Expect = e-100 Identities = 205/451 (45%), Positives = 277/451 (61%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++ D + I EK RQ + +ELI SEN+ S V++A GSV+TNKY+EGYPG RYYGG Sbjct: 8 IKNFDDVLFKAISDEKRRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L RA F VNVQP SGS AN V ALL P D M + LPH Sbjct: 68 CEFVDVAEELAISRAKLLFGAHY----VNVQPHSGSQANAAVMMALLSPGDTFMGMALPH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K++ + ++ Y +D +TGLIDYD LEK A+ +PKLI+AG SAY Sbjct: 124 GGHLTHG-----SKVNFSGKLYHSVEYGVDNNTGLIDYDALEKLALQHKPKLIIAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R+ D+ R R+I DK A L+AD+AH++GLVA G+ PSP YADVVTTTTHK+LRGPRG Sbjct: 179 SRILDWARFREIADKVGAYLMADIAHVAGLVAVGLYPSPVPYADVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + K+ +E+ E K+N+AVFPG+QGGP H I AVA +A E++ Sbjct: 239 LI--------LCKENEEI----EKKLNSAVFPGMQGGPLMHVIAAKAVAFAEALLPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV++N+ L S+GYDIVSGGTDNHL+LV+L KGI G + L +I NK Sbjct: 287 YQQQVLANARTMCSVLQSRGYDIVSGGTDNHLLLVDLINKGITGKEADAALGRANITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R+GTPA T+RGF E + T L Sbjct: 347 NSVPNDPRSPFVTSGLRLGTPAATTRGFKEREI-----------------------TLLS 383 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 ++VA + + + + I++++ V ++FP Sbjct: 384 NWVADVLDNVHDETNISRVKTQVLLLCREFP 414
>Q6AM21:GLYA_DESPS Serine hydroxymethyltransferase - Desulfotalea psychrophila| Length = 425 Score = 363 bits (933), Expect = 1e-99 Identities = 200/456 (43%), Positives = 275/456 (60%), Gaps = 1/456 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L++ DPEI +I+ E+ RQ + LI SEN+ S +V++A GS++TNKYSEGYPG RYY G Sbjct: 13 LQQQDPEIFSLIQQEEVRQHNKIRLIASENYVSSAVLEATGSILTNKYSEGYPGKRYYEG 72 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 + ID E++ RA F + VNVQP SGSPAN VY A LKP D I+ + LPH Sbjct: 73 QQLIDQIESIAIDRAKAVFGAEH----VNVQPYSGSPANMAVYLAFLKPGDTILGMALPH 128 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K+S +F + Y L+E G++DY+++ A+ +PK+++AG SAY Sbjct: 129 GGHLTHG-----SKVSISGKYFNAVSYALNEE-GILDYEEIRNKALECKPKILIAGHSAY 182 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ + R+I D+ A+L+ DMAH +GLVA GV PSPF YADVVTTTTHKSLRGPRGA Sbjct: 183 PRILDFAKFREIADEVGALLMVDMAHFAGLVAGGVHPSPFPYADVVTTTTHKSLRGPRGA 242 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI K ++ I+ AVFPG+QGGPH+ T +AVALK+A+T ++ Sbjct: 243 MIM--------------CKAEYAKAIDKAVFPGMQGGPHDSTTAAIAVALKEASTDSFKK 288 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV+ N+A A+ L KG+++V+GGT+NHL+L++L K I G + K L+ I N Sbjct: 289 YTAQVVENAASLADVLIEKGFNLVTGGTENHLMLIDLSNKNITGKQAAKALDAAGIVLNC 348 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D P GIR+GT A+TSRGF + + + D Sbjct: 349 NSVPFDKRKPFDPSGIRLGTCAITSRGFAKAEMVILGNMMDR------------------ 390 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIGFE 1592 V DS + AEIA+ +V+ +FP G E Sbjct: 391 --VVNNFEDSAVLAEIAQ---EVQALCDKFPAPGLE 421
>Q5ZXK6:GLYA_LEGPH Serine hydroxymethyltransferase - Legionella pneumophila subsp.| pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) Length = 417 Score = 363 bits (931), Expect = 2e-99 Identities = 203/451 (45%), Positives = 277/451 (61%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++ D + I EK RQ + +ELI SEN+ S V++A GSV+TNKY+EGYPG RYYGG Sbjct: 8 IKNFDDVLFKAISDEKRRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L RA F VNVQP SGS AN V ALL P D M + LPH Sbjct: 68 CEFVDVAEELAISRAKLLFGAHY----VNVQPHSGSQANAAVMMALLSPGDTFMGMALPH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K++ + ++ Y +D +TGLIDYD LEK A+ +PKLI+AG SAY Sbjct: 124 GGHLTHG-----SKVNFSGKLYHSVEYGVDSNTGLIDYDALEKLALQHKPKLIIAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R+ D+ R R+I DK A L+AD+AH++GLVA G+ PSP YADVVTTTTHK+LRGPRG Sbjct: 179 SRILDWARFREIADKVGAYLMADIAHVAGLVAVGLYPSPVPYADVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + K+ +E+ E K+N++VFPG+QGGP H I AVA +A E++ Sbjct: 239 LI--------LCKENEEI----EKKLNSSVFPGMQGGPLMHVIAAKAVAFAEALLPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV++N+ L S+GYDIVSGGTDNHL+LV+L KGI G + + +I NK Sbjct: 287 YQQQVLANARTMCSVLQSRGYDIVSGGTDNHLLLVDLINKGITGKEADAAVGRANITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R+GTPA T+RGF E + T L Sbjct: 347 NSVPNDPRSPFVTSGLRLGTPAATTRGFKEREI-----------------------TLLS 383 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 ++VA + + + + I++++ V ++FP Sbjct: 384 NWVADVLDNVHDETNISRVKTQVLLLCREFP 414
>Q5X722:GLYA_LEGPA Serine hydroxymethyltransferase - Legionella pneumophila (strain| Paris) Length = 417 Score = 363 bits (931), Expect = 2e-99 Identities = 203/451 (45%), Positives = 277/451 (61%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++ D + I EK RQ + +ELI SEN+ S V++A GSV+TNKY+EGYPG RYYGG Sbjct: 8 IKNFDDVLFKAISDEKRRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L RA F VNVQP SGS AN V ALL P D M + LPH Sbjct: 68 CEFVDVAEELAISRAKLLFGAHY----VNVQPHSGSQANAAVMMALLSPGDTFMGMALPH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K++ + ++ Y +D +TGLIDYD LEK A+ +PKLI+AG SAY Sbjct: 124 GGHLTHG-----SKVNFSGKLYHSVEYGVDSNTGLIDYDALEKLALQHKPKLIIAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R+ D+ R R+I DK A L+AD+AH++GLVA G+ PSP YADVVTTTTHK+LRGPRG Sbjct: 179 SRILDWARFREIADKVGAYLMADIAHVAGLVAVGLYPSPVPYADVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + K+ +E+ E K+N++VFPG+QGGP H I AVA +A E++ Sbjct: 239 LI--------LCKENEEI----EKKLNSSVFPGMQGGPLMHVIAAKAVAFAEALLPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV++N+ L S+GYDIVSGGTDNHL+LV+L KGI G + + +I NK Sbjct: 287 YQQQVLANARTMCSVLQSRGYDIVSGGTDNHLLLVDLINKGITGKEADAAVGRANITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R+GTPA T+RGF E + T L Sbjct: 347 NSVPNDPRSPFVTSGLRLGTPAATTRGFKEREI-----------------------TLLS 383 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 ++VA + + + + I++++ V ++FP Sbjct: 384 NWVADVLDNVHDETNISRVKTQVLLLCREFP 414
>Q8R887:GLYA_THETN Serine hydroxymethyltransferase - Thermoanaerobacter tengcongensis| Length = 413 Score = 361 bits (927), Expect = 5e-99 Identities = 189/398 (47%), Positives = 258/398 (64%), Gaps = 1/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + DPEIA++I E RQ +ELI SENF S +VM+A+G+ +TNKY+EGYPG RYYGG Sbjct: 6 IRKTDPEIAEVILKELNRQRNKIELIASENFVSRAVMEAMGTPLTNKYAEGYPGRRYYGG 65 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+DMAE L ++R + F + NVQP SG+ AN Y ALLKP D ++ +DL H Sbjct: 66 CEYVDMAEELARERLKKLFGAEH----ANVQPHSGAQANMAAYFALLKPGDTVLGMDLAH 121 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K++ + + Y + E TG IDYDQ+E A +PKLIVAGASAY Sbjct: 122 GGHLTHG-----SKVNFSGQIYNFVSYGVREDTGYIDYDQVEDLAKKHKPKLIVAGASAY 176 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ + R+I DK A L+ DMAHI+GLVAAG+ P+P YADVVTTTTHK+LRGPRG Sbjct: 177 PRIIDFKKFREIADKVGAYLMVDMAHIAGLVAAGLHPNPVPYADVVTTTTHKTLRGPRGG 236 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 I K + I+ A+FPG QGGP H I AV K+A + E++ Sbjct: 237 AIL--------------CKQEHAKAIDKALFPGTQGGPLMHIIAAKAVCFKEALSDEFKE 282 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ++++ N+ A +L +G ++VSGGTDNHL+L++L+ GI G +E L+ V+I NK Sbjct: 283 YQKRIVENAKALANALMERGINLVSGGTDNHLMLLDLRNTGITGKELETRLDEVNITCNK 342 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 N +P D + V G+R+GTPA+T+RG ED ++A+ Sbjct: 343 NAIPFDPLGPNVTSGVRLGTPAVTTRGMKPEDMVEIAD 380
>Q6FA66:GLYA_ACIAD Serine hydroxymethyltransferase - Acinetobacter sp. (strain ADP1)| Length = 417 Score = 361 bits (926), Expect = 7e-99 Identities = 198/402 (49%), Positives = 256/402 (63%), Gaps = 1/402 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N L E DPE+A IE E ARQ +ELI SEN+ S +VM+A GS +TNKY+EGYPG RY Sbjct: 4 NISLSEFDPELAKSIEAEDARQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRY 63 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG EY+D+ E L RA F D NVQP +GS AN VY ALL D ++ + Sbjct: 64 YGGCEYVDVIEQLAIDRAKALFGADY----ANVQPHAGSQANSAVYLALLNAGDTVLGMS 119 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG K++ + + Y L+ TG IDYD++E+ A+ +P++IVAG Sbjct: 120 LAHGGHLTHG-----AKVNFSGKTYNAVQYGLNPETGEIDYDEVERLAIEHKPRMIVAGF 174 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY+R+ D+ R R I DK A L DMAH++GLVAAGV PSP + ADV TTTTHK+LRGP Sbjct: 175 SAYSRIVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPSPVQIADVTTTTTHKTLRGP 234 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 R +I + K +E+ E K+ +AVFPG QGGP H I AV K+A E Sbjct: 235 RSGLI--------LAKANEEI----EKKLQSAVFPGNQGGPLVHAIAAKAVCFKEAMAPE 282 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 Y+AYQ+QV+ N+ AE L ++GYDIVSGGTDNHL L++L K+ + G + L N +I Sbjct: 283 YKAYQQQVVKNAQAMAEVLIARGYDIVSGGTDNHLFLLSLIKQDVTGKEADAWLGNANIT 342 Query: 1299 ANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NKN VP D S V GIR+GTPA+T+RGF E + +A + Sbjct: 343 VNKNAVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRDLASW 384
>Q8KC36:GLYA_CHLTE Serine hydroxymethyltransferase - Chlorobium tepidum| Length = 440 Score = 360 bits (925), Expect = 9e-99 Identities = 205/460 (44%), Positives = 276/460 (60%), Gaps = 7/460 (1%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N L+ +DPE+ + I E RQ + LELI SENFTS +VM+A GSVMTNKY+EGYPG RY Sbjct: 3 NDILKRLDPEVFEAIANETKRQTETLELIASENFTSKAVMEACGSVMTNKYAEGYPGKRY 62 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG E++D+AE L + RA + F + VNVQP SGS AN V A+LKP D IM LD Sbjct: 63 YGGCEFVDVAENLARDRAKKLFGCEY----VNVQPHSGSSANMAVLFAVLKPGDAIMGLD 118 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG K++ FF+ Y +D+ TG+ID +++E+ A +PKLI+ GA Sbjct: 119 LSHGGHLTHG-----SKVNFSGQFFDAHSYGVDKETGIIDMNKVEEMARRVKPKLIITGA 173 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY++ +D+ R++ DK A+L+AD+AH +GLVAAG+ +P + VTTTTHK+LRGP Sbjct: 174 SAYSQGFDFKAFREVADKVGALLMADIAHPAGLVAAGLSANPMPHCHFVTTTTHKTLRGP 233 Query: 939 RGAMIFFRK------GVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALK 1100 RG MI K G+ K G VK + I+A V PG+QGGP H I G AVA Sbjct: 234 RGGMIMMGKDFENPLGLTINTKNGSRVKM-MSEVIDAEVMPGIQGGPLMHIIAGKAVAFG 292 Query: 1101 QATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVL 1280 +A E++AY +Q+ N+A A + GY IVSGGT NHL+L++L+ K ++G E +L Sbjct: 293 EALQPEFKAYAQQIKDNAAAMAAKFLAAGYHIVSGGTKNHLMLLDLRNKNVNGKVAENLL 352 Query: 1281 ENVHIAANKNTVP-GDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXX 1457 I NKN VP D S V GIR+GTPA+T+RG + K+ EF D Sbjct: 353 HEAGITVNKNMVPFDDKSPFVTSGIRIGTPAMTTRGMKVAEAEKIVEFIDR--------- 403 Query: 1458 XXXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 V + +D+N+ +R +V E FP Sbjct: 404 -----------VISAANDANVADVCKAVRAEVRELCLGFP 432
>Q97GV1:GLYA_CLOAB Serine hydroxymethyltransferase - Clostridium acetobutylicum| Length = 411 Score = 360 bits (924), Expect = 1e-98 Identities = 194/398 (48%), Positives = 261/398 (65%), Gaps = 2/398 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D E+ IIE E ARQ +ELI SENFTS +VM+A+GS +TNKY+EGYPG RYYGG + Sbjct: 10 DSEVYSIIEEENARQENNIELIASENFTSKAVMEAMGSYLTNKYAEGYPGKRYYGGCYVV 69 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D E L ++RA + F + NVQP SGS AN VY A+LKP D IM ++L GGHL Sbjct: 70 DKVEELARERAKKLFKAEH----ANVQPHSGSQANMAVYFAVLKPGDTIMGMNLTDGGHL 125 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F + Y + + T IDY+ K A+ +PK+IV+GASAY+R+ Sbjct: 126 THG-----SPVNFSGKLFNIIAYGVSDETEQIDYEAFRKKALECKPKMIVSGASAYSRII 180 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ ++R+ICD+ A ++ DMAHI+GLVAAG+ PSP YAD VTTTTHK+LRGPRG IF Sbjct: 181 DFKKIREICDEVGAYMMVDMAHIAGLVAAGLHPSPIPYADFVTTTTHKTLRGPRGGAIFC 240 Query: 960 R-KGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQE 1136 + K K+I+K +VFPG+QGGP H I G AV +A +++ Y + Sbjct: 241 KEKYAKDIDK---------------SVFPGMQGGPLMHIIAGKAVCFGEALKDDFKDYAQ 285 Query: 1137 QVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTV 1316 Q+++N+ FA+ LT G+ IVSGGTDNHL+LV+L K I G E +L++V I ANKNT+ Sbjct: 286 QIVNNAKVFADELTKYGFRIVSGGTDNHLLLVDLTNKNITGKDAEHLLDSVGITANKNTI 345 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 P + S + GIRMGTP++T+RGF EE+ KVA F + Sbjct: 346 PFEKKSPFITSGIRMGTPSVTTRGFKEEEMKKVAYFIN 383
>Q3AW18:GLYA_SYNS9 Serine hydroxymethyltransferase - Synechococcus sp. (strain CC9902)| Length = 429 Score = 358 bits (920), Expect = 3e-98 Identities = 198/404 (49%), Positives = 259/404 (64%), Gaps = 1/404 (0%) Frame = +3 Query: 210 KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPG 389 + +NA L DPEI+ +I+ E+ RQ LELI SENF S +VMQA GSV+TNKY+EG P Sbjct: 7 RAINAGLASADPEISRLIDQERHRQETHLELIASENFASQAVMQAQGSVLTNKYAEGLPA 66 Query: 390 ARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIM 569 RYYGG E++D ETL +RA + F+ W NVQP SG+ ANF V+ ALLKP D IM Sbjct: 67 KRYYGGCEHVDAIETLAIERAKQLFDA---AWA-NVQPHSGAQANFAVFLALLKPGDTIM 122 Query: 570 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIV 749 LDL HGGHL+HG ++ +F + Y +D +T +D + + K A+ +PKLIV Sbjct: 123 GLDLSHGGHLTHG-----SPVNVSGKWFNVVQYGVDPTTQRLDMEAIRKLALEHKPKLIV 177 Query: 750 AGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSL 929 G SAY R D+ R I D+ A LLADMAHI+GLVAAGV PSP + DVVTTTTHK+L Sbjct: 178 CGYSAYPRTIDFAAFRSIADEVGAFLLADMAHIAGLVAAGVHPSPVPHCDVVTTTTHKTL 237 Query: 930 RGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQAT 1109 RGPRG +I R +F K + AVFPG QGGP H I AVA +A Sbjct: 238 RGPRGGLILCRDA-------------EFAKKFDKAVFPGTQGGPLEHVIAAKAVAFGEAL 284 Query: 1110 TQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENV 1289 ++ Y +QV++N+ AE L S+G ++VSGGTDNH+VL++L+ G+ G + ++ +V Sbjct: 285 QPSFKTYSQQVVANAGALAEQLISRGINVVSGGTDNHVVLLDLRSIGMTGKVADLLVSDV 344 Query: 1290 HIAANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 HI ANKNTVP D S V G+R+GT ALT+RGF + F +VA+ Sbjct: 345 HITANKNTVPFDPESPFVTSGLRLGTAALTTRGFDVDAFREVAD 388
>Q3K5K9:GLYA3_PSEPF Serine hydroxymethyltransferase 3 - Pseudomonas fluorescens (strain| PfO-1) Length = 417 Score = 358 bits (920), Expect = 3e-98 Identities = 192/388 (49%), Positives = 251/388 (64%), Gaps = 1/388 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++ D + + E+ RQ +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IQGYDDALLAAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L +RA + F D NVQP SGS AN VY ALL+ D I+ + L H Sbjct: 68 CEHVDKVEALAIERAKQLFGADY----ANVQPHSGSSANSAVYLALLQAGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K+S+ + + Y +D TGLIDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----AKVSSSGKLYNAVQYGIDTKTGLIDYDEVERLAVECKPKMIVAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R+I DK A+L DMAH++GLVAAG+ P+P YADVVTTTTHK+LRGPRG Sbjct: 179 SKTLDFPRFRQIADKVGALLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + K +E+ E K+NAAVFPG QGGP H I G AV K+A ++A Sbjct: 239 LI--------LAKANEEI----EKKLNAAVFPGAQGGPLMHVIAGKAVCFKEALEPGFKA 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +GYD+VSGGTDNHL LV+L ++G+ G + L HI NK Sbjct: 287 YQQQVIDNAQAMASVFIKRGYDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGF 1388 N VP D S V G+R+GTPA+T+RGF Sbjct: 347 NAVPNDPQSPFVTSGLRIGTPAVTTRGF 374
>Q9WZH9:GLYA_THEMA Serine hydroxymethyltransferase - Thermotoga maritima| Length = 427 Score = 358 bits (919), Expect = 5e-98 Identities = 192/401 (47%), Positives = 257/401 (64%), Gaps = 1/401 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +++VDPEI +++ E RQ GLELI SENF SL+V++ +GS++TNKY+EGYP RYYGG Sbjct: 5 VKQVDPEIYEVLVNELKRQEYGLELIASENFASLAVIETMGSMLTNKYAEGYPKKRYYGG 64 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D AE +RA F NVQP SGS AN VY AL +P D IM + L H Sbjct: 65 CEWVDRAEERAIERAKRLFGAK----FANVQPHSGSQANMAVYLALAQPGDTIMGMSLSH 120 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ F+ +PY ++ T IDYD++ + A+ +PK+IVAG SAY Sbjct: 121 GGHLTHG-----APVNFSGKIFKVVPYGVNLETETIDYDEVRRLALEHKPKIIVAGGSAY 175 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 AR+ D+ R R+I D+ A L+ DMAH +GLVAAG+ P+P EYA VVT+TTHK+LRGPRG Sbjct: 176 ARIIDFKRFREIADEVGAYLMVDMAHFAGLVAAGIHPNPLEYAHVVTSTTHKTLRGPRGG 235 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I EI K ++ +FPG+QGGP H I AV K+A T+E++ Sbjct: 236 LILTND--PEIAK-----------AVDKTIFPGIQGGPLMHVIAAKAVCFKEAMTEEFKE 282 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ + AE +GY IVSGGTD HL LV+L K I G EK LE+ I NK Sbjct: 283 YQKQVVKNAKKMAEEFQKRGYRIVSGGTDTHLFLVDLTPKDITGKAAEKALESCGITVNK 342 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 NT+P + S V GIR+GTPA+T+RG EE+ ++AE D Sbjct: 343 NTIPNEKRSPFVASGIRIGTPAVTTRGMKEEEMEEIAEMID 383
>Q3B2I7:GLYA_PELLD Serine hydroxymethyltransferase - Pelodictyon luteolum (strain DSM| 273) (Chlorobium luteolum (strain DSM 273)) Length = 440 Score = 358 bits (919), Expect = 5e-98 Identities = 198/407 (48%), Positives = 260/407 (63%), Gaps = 7/407 (1%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ D E+ D I E RQ + LELI SENFTS +VMQA GSVMTNKY+EGYPG RYYGG Sbjct: 6 LKMQDREVFDAIAGETVRQMETLELIASENFTSRAVMQACGSVMTNKYAEGYPGKRYYGG 65 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L ++RA + F + VNVQP SGS AN V ++LKP DRIM LDL H Sbjct: 66 CEFVDIAEDLARERARKLFGCEY----VNVQPHSGSSANMAVLFSVLKPGDRIMGLDLSH 121 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ F+ Y +D TG+ID +++E+ A+ F+P+LI+ GASAY Sbjct: 122 GGHLTHG-----SSVNFSGQMFDARSYGVDRETGIIDMNKVEEMALDFKPRLIICGASAY 176 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ +D+ R+I DK A L+AD+AH +GL+AAG++ P + VTTTTHK+LRGPRG Sbjct: 177 SQGFDFKAFREIADKVGAFLMADIAHPAGLIAAGLLTDPMPHCHFVTTTTHKTLRGPRGG 236 Query: 948 MIFFRK------GVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQAT 1109 MI K G+ K G VK + ++A V PG+QGGP H I G AVA +A Sbjct: 237 MIMMGKDFENPMGITIKTKNGPRVKM-MSEVMDAEVMPGIQGGPLMHIIAGKAVAFGEAL 295 Query: 1110 TQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENV 1289 E+R Y QV N+A AE TS GY+IVSGGT NHL+L++L+ K ++G E +L + Sbjct: 296 RPEFREYAVQVRKNAASMAERFTSLGYNIVSGGTKNHLMLLDLRNKDVNGKVAENLLHDA 355 Query: 1290 HIAANKNTVP-GDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 I NKN VP D S V GIR+GT A+T+RG E D +AE D Sbjct: 356 GITVNKNMVPFDDKSPFVTSGIRIGTAAMTTRGMKEADATLIAELID 402
>Q4K4P6:GLYA2_PSEF5 Serine hydroxymethyltransferase 2 - Pseudomonas fluorescens (strain| Pf-5 / ATCC BAA-477) Length = 417 Score = 357 bits (917), Expect = 8e-98 Identities = 192/388 (49%), Positives = 250/388 (64%), Gaps = 1/388 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++ D + I E+ RQ +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IQGYDDALLAAINAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L +RA + F D NVQP SGS AN VY ALL+ D I+ + L H Sbjct: 68 CEHVDKVEALAIERAKQLFGADY----ANVQPHSGSSANSEVYLALLQAGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K+S+ + + Y +D TGLIDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----AKVSSSGKLYNAVQYGIDTRTGLIDYDEVERLAVEHKPKMIVAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R+I DK A+L DMAH++GLVAAG+ P+P YADVVTTTTHK+LRGPRG Sbjct: 179 SKTLDFPRFRQIADKVGALLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + K +E+ E K+NAAVFPG QGGP H I AV K+A ++A Sbjct: 239 LI--------LAKANEEI----EKKLNAAVFPGAQGGPLMHVIAAKAVCFKEALEPGFKA 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +GYD+VSGGTDNHL LV+L ++G+ G + L HI NK Sbjct: 287 YQQQVIDNAQAMAGVFIKRGYDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGF 1388 N VP D S V G+R+GTPA+T+RGF Sbjct: 347 NAVPNDPQSPFVTSGLRIGTPAVTTRGF 374
>Q4K5R9:GLYA1_PSEF5 Serine hydroxymethyltransferase 1 - Pseudomonas fluorescens (strain| Pf-5 / ATCC BAA-477) Length = 417 Score = 357 bits (916), Expect = 1e-97 Identities = 200/454 (44%), Positives = 272/454 (59%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D ++ +E E RQ + +ELI SEN+TS +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 8 IAKYDADLFAAMEQEAQRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP +GS AN VY ALL+ D I+ + L H Sbjct: 68 CEYVDVVEQLAIDRAKELFGADY----ANVQPHAGSQANAAVYLALLQGGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG +S+ + + Y +D + GLIDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----AAVSSSGKLYNAIQYGID-ANGLIDYDEVERLAVEHKPKMIVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ R R+I DK A L DMAH++GLVAAGV P+P +ADVVTTTTHK+LRGPRG Sbjct: 178 SQILDFPRFREIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R D E K+N+AVFPG QGGP H I A+ K+A E++A Sbjct: 238 LILARANA------------DIEKKLNSAVFPGAQGGPLEHVIAAKAICFKEALQPEFKA 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQEQV+ N+ AE ++G+D+VSGGT NHL L++L K+ I G + L I NK Sbjct: 286 YQEQVVKNAQAMAEVFIARGFDVVSGGTKNHLFLLSLIKQDISGKDADAALGKAFITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R GTPA+T+RGF E + ++A Sbjct: 346 NSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELA----------------------- 382 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 ++ + +D N +A I +R V+ K+ P G Sbjct: 383 GWICDILADLNNEAVIDAVREKVKAICKKLPVYG 416
>Q39V87:GLYA_GEOMG Serine hydroxymethyltransferase - Geobacter metallireducens (strain| GS-15 / ATCC 53774 / DSM 7210) Length = 415 Score = 357 bits (915), Expect = 1e-97 Identities = 191/399 (47%), Positives = 252/399 (63%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE DP +A+ I E RQ LELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 4 LETFDPAVAEAIRHETERQEYNLELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 ++D+ E L +RA E F D NVQP SGS AN VY ++LKP D I+ ++L H Sbjct: 64 CHHVDVVENLAIERAKELFGADH----ANVQPHSGSQANMAVYFSVLKPGDTILGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ FF +PY + + T ID++++E+ A+ +PKLIV GASAY Sbjct: 120 GGHLTHG-----SPVNFSGRFFNVVPYGVSQETETIDFNEVERLALEHKPKLIVVGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ R I DK A+++ DMAHI+GLVAAG+ PSP YA+ VTTTTHK+LRGPRG Sbjct: 175 PRVLDFAAFRAIADKVGALVMVDMAHIAGLVAAGLHPSPVPYAEFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI R+ +F +N+ +FPG+QGGP H I AVA K+A E++ Sbjct: 235 MILCRE--------------EFAKTLNSNIFPGIQGGPLMHVIAAKAVAFKEALAPEFKL 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQEQ++ N+ A+ L +G+ +VSGGTDNHL+LVNL + G E+ L+ I NK Sbjct: 281 YQEQIVKNARTLADELMKRGFRLVSGGTDNHLMLVNLTGTELTGKVAEEALDKAGITVNK 340 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NTVP + S V G R+GTPA TS G E + +VA F Sbjct: 341 NTVPFETRSPFVTSGFRIGTPAATSHGLKEAEMVEVAAF 379
>Q3A934:GLYA_CARHZ Serine hydroxymethyltransferase - Carboxydothermus hydrogenoformans| (strain Z-2901 / DSM 6008) Length = 421 Score = 357 bits (915), Expect = 1e-97 Identities = 188/402 (46%), Positives = 266/402 (66%), Gaps = 1/402 (0%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 LN L++VDPEI + +E E +RQ + +ELI SENF S +VM+A+GS +TNKY+EG PG R Sbjct: 4 LNLRLKDVDPEIFEAMEKELSRQREKIELIASENFVSRAVMEAMGSHLTNKYAEGLPGKR 63 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 YYGG EY+D+ E L ++RA + F + VNVQP SG+ AN Y A L+P D ++ + Sbjct: 64 YYGGCEYVDVVENLARERAKKLFGAEH----VNVQPHSGAQANMAAYMAFLEPGDTVLGM 119 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 +L HGGHL+HG ++ + + Y ++ T I+Y+++ + A +PK+IVAG Sbjct: 120 NLAHGGHLTHG-----SPVNFSGKLYNFVSYGVEPDTEKINYEKVFELAYKHKPKMIVAG 174 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 ASAY R+ D+ +++I D+ A L+ DMAHI+GLVAAG+ PSP YADVVTTTTHK+LRG Sbjct: 175 ASAYPRVIDFKHLKEIADEVGAYLMVDMAHIAGLVAAGLHPSPIPYADVVTTTTHKTLRG 234 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG +IF K + KI+ VFPG+QGGP H I AVA K+A + Sbjct: 235 PRGGVIF--------------CKAEHAAKIDKTVFPGVQGGPLMHVIAAKAVAFKEALSP 280 Query: 1116 EYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHI 1295 E+R YQ+QV++N+ AE L +G +VSGGTDNHL+LV+++ G+ G R E++L+ + + Sbjct: 281 EFREYQQQVVNNAKALAEELKKQGLRLVSGGTDNHLMLVDVRPVGLTGKRAEQLLDEIGV 340 Query: 1296 AANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 NKN +P D S V GIR+GTPA+T+RG E + A++AE Sbjct: 341 TVNKNAIPYDPESPNVTSGIRIGTPAVTTRGMKEGEMAEIAE 382
>Q9HTE9:GLYA1_PSEAE Serine hydroxymethyltransferase 1 - Pseudomonas aeruginosa| Length = 417 Score = 357 bits (915), Expect = 1e-97 Identities = 193/393 (49%), Positives = 249/393 (63%), Gaps = 1/393 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D E+ ++ E+ARQ LELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG E++ Sbjct: 12 DDELLAAMDAEEARQEDHLELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHV 71 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D E L RA + F D NVQP SGS AN VY ALL D I+ + L HGGHL Sbjct: 72 DKVERLAIDRARQLFGADY----ANVQPHSGSSANAAVYLALLNAGDTILGMSLAHGGHL 127 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG K+S+ + + Y LD +TGLIDYD++E+ AV +PK+IVAG SAY++ Sbjct: 128 THG-----AKVSSSGKLYNAVQYGLDTATGLIDYDEVERLAVEHKPKMIVAGFSAYSKTL 182 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R R I DK A+L DMAH++GLVAAG+ P+P +ADVVTTTTHK+LRGPRG +I Sbjct: 183 DFPRFRAIADKVGALLFVDMAHVAGLVAAGLYPNPIPFADVVTTTTHKTLRGPRGGLILA 242 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 R + E K+N+AVFPG QGGP H I AV K+A ++ YQ Q Sbjct: 243 R------------ANEEIEKKLNSAVFPGAQGGPLMHVIAAKAVCFKEALEPGFKDYQAQ 290 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V+ N+ AE +GYD+VSGGTDNHL+L++L ++G+ G + L V I NKN VP Sbjct: 291 VIRNAKAMAEVFIGRGYDVVSGGTDNHLMLISLVRQGLTGKEADAALGRVGITVNKNAVP 350 Query: 1320 GD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 D S V GIR+GTPA+T+RG E ++A Sbjct: 351 NDPQSPFVTSGIRIGTPAITTRGLQEAQSRELA 383
>Q3YZ04:GLYA_SHISS Serine hydroxymethyltransferase - Shigella sonnei (strain Ss046)| Length = 417 Score = 356 bits (914), Expect = 2e-97 Identities = 194/397 (48%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L H Sbjct: 68 CEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +D +TG IDY LEK A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGID-ATGHIDYADLEKQAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GLVAAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFPG QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGSEELYK-----------KLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E +GY +VSGGTDNHL LV+L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+GTPA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELA 383
>P0A827:GLYA_SHIFL Serine hydroxymethyltransferase - Shigella flexneri| Length = 417 Score = 356 bits (914), Expect = 2e-97 Identities = 194/397 (48%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L H Sbjct: 68 CEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +D +TG IDY LEK A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGID-ATGHIDYADLEKQAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GLVAAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFPG QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGSEELYK-----------KLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E +GY +VSGGTDNHL LV+L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+GTPA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELA 383
>Q32D21:GLYA_SHIDS Serine hydroxymethyltransferase - Shigella dysenteriae serotype 1| (strain Sd197) Length = 417 Score = 356 bits (914), Expect = 2e-97 Identities = 194/397 (48%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L H Sbjct: 68 CEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFTVYTALLEPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +D +TG IDY LEK A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGID-ATGHIDYADLEKQAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GLVAAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFPG QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGSEELYK-----------KLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E +GY +VSGGTDNHL LV+L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+GTPA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELA 383
>Q31XT6:GLYA_SHIBS Serine hydroxymethyltransferase - Shigella boydii serotype 4 (strain| Sb227) Length = 417 Score = 356 bits (914), Expect = 2e-97 Identities = 194/397 (48%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L H Sbjct: 68 CEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +D +TG IDY LEK A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGID-ATGHIDYADLEKQAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GLVAAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFPG QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGSEELYK-----------KLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E +GY +VSGGTDNHL LV+L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+GTPA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELA 383
>P0A825:GLYA_ECOLI Serine hydroxymethyltransferase - Escherichia coli| Length = 417 Score = 356 bits (914), Expect = 2e-97 Identities = 194/397 (48%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L H Sbjct: 68 CEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +D +TG IDY LEK A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGID-ATGHIDYADLEKQAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GLVAAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFPG QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGSEELYK-----------KLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E +GY +VSGGTDNHL LV+L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+GTPA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELA 383
>P0A826:GLYA_ECOL6 Serine hydroxymethyltransferase - Escherichia coli O6| Length = 417 Score = 356 bits (914), Expect = 2e-97 Identities = 194/397 (48%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L H Sbjct: 68 CEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +D +TG IDY LEK A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGID-ATGHIDYADLEKQAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GLVAAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFPG QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGSEELYK-----------KLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E +GY +VSGGTDNHL LV+L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+GTPA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELA 383
>Q8XA55:GLYA_ECO57 Serine hydroxymethyltransferase - Escherichia coli O157:H7| Length = 417 Score = 356 bits (913), Expect = 2e-97 Identities = 194/397 (48%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L H Sbjct: 68 CEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +D +TG IDY LEK A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGID-ATGHIDYADLEKQAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GLVAAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFPG QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGSEELYK-----------KLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E +GY +VSGGTDNHL LV+L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+GTPA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRVGTPAITRRGFKEVEAKELA 383
>Q2SFI7:GLYA1_HAHCH Serine hydroxymethyltransferase 1 - Hahella chejuensis (strain KCTC| 2396) Length = 426 Score = 356 bits (913), Expect = 2e-97 Identities = 189/399 (47%), Positives = 256/399 (64%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + DPE++ I EK RQ + +ELI SEN+ S VM+A G V+TNKY+EGYPG RYYGG Sbjct: 8 IADYDPELSAAINAEKRRQEEHIELIASENYVSPRVMEAQGGVLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L RA + F D NVQP SGS AN VY AL KP D I+ + L H Sbjct: 68 CEHVDVAEQLAIDRAKQLFGADY----ANVQPHSGSQANAGVYLALAKPGDTILGMSLDH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K + F + Y L+ TG IDYDQ+E+ A +PKL++AG SAY Sbjct: 124 GGHLTHG-----AKPNFSGKIFNAVQYGLNPETGEIDYDQVERLAKEHKPKLVIAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R+ D+ R R I D A L+ DMAH++GLVAAG+ PSP + ADV TTTTHK+LRGPRG Sbjct: 179 SRVVDWQRFRDIADSVGAYLIVDMAHVAGLVAAGLYPSPVQIADVTTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + K E+ E K+ + +FPG+QGGP H I AVA K+A +R Sbjct: 239 LI--------LAKSNPEI----EKKLQSLIFPGIQGGPLMHVIAAKAVAFKEALEPAFRD 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV++N+ A+++ ++GY +VSGGTDNHL L++L KG+ G + L +I NK Sbjct: 287 YQQQVVNNARAMADAVKARGYKVVSGGTDNHLFLIDLIDKGVTGKDADAALGRAYITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NTVP D S V G+R+GTP +T+RGF E++ ++A + Sbjct: 347 NTVPNDPQSPFVTSGLRIGTPGVTTRGFKEKEVVELANW 385
>Q74CR5:GLYA_GEOSL Serine hydroxymethyltransferase - Geobacter sulfurreducens| Length = 415 Score = 355 bits (912), Expect = 3e-97 Identities = 191/399 (47%), Positives = 253/399 (63%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE DP++A+ I E RQ LELI SENF S +V++A GSVMTNKY+EGYPG RYYGG Sbjct: 4 LETFDPQVAEAIRHETERQEYNLELIASENFVSEAVLEAQGSVMTNKYAEGYPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 ++D+ E L +RA E F D NVQP SGS AN VY ++LKP D I+ ++L H Sbjct: 64 CHHVDVVENLAIERAKELFGADH----ANVQPHSGSQANMAVYFSVLKPGDTILGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ FF +PY + + T ID++++E+ A+ +PK+IV GASAY Sbjct: 120 GGHLTHG-----SPVNFSGRFFNVVPYGVSQETETIDFNEVERLALEHKPKMIVVGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ R I DK AV++ DMAHI+GLVAAG+ PSP YA+ VTTTTHK+LRGPRG Sbjct: 175 PRTIDFAAFRIIADKVGAVIMVDMAHIAGLVAAGLHPSPVPYAEFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI R+ ++ +N+ +FPG+QGGP H I AVALK+A E++A Sbjct: 235 MILCRE--------------EYAKTLNSNIFPGIQGGPLMHVIAAKAVALKEALQPEFKA 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ Q++ N+ A+ L +G+ +VSGGTDNHL+LVNL + G E+ L+ I NK Sbjct: 281 YQAQIVKNAKALADELVKRGFRLVSGGTDNHLMLVNLTGTELTGKVAEESLDKAGITVNK 340 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NTVP + S V G R+GTPA T+ G E + A VA F Sbjct: 341 NTVPFETRSPFVTSGFRIGTPAATTHGLKEAEMADVAGF 379
>Q88R12:GLYA1_PSEPK Serine hydroxymethyltransferase 1 - Pseudomonas putida (strain| KT2440) Length = 417 Score = 355 bits (912), Expect = 3e-97 Identities = 190/388 (48%), Positives = 251/388 (64%), Gaps = 1/388 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++ D + + E+ RQ +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IQGYDDALLAAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L +RA + F D NVQP SGS AN VY ALL+ D I+ + L H Sbjct: 68 CEHVDKVEALAIERAKQLFGADY----ANVQPHSGSSANGAVYLALLQAGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K+S+ + + Y +D +TGLIDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----AKVSSSGKLYNAVQYGIDTNTGLIDYDEVERLAVEHKPKMIVAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R I DK A+L DMAH++GLVAAG+ P+P +ADVVTTTTHK+LRGPRG Sbjct: 179 SKTLDFPRFRAIADKVGALLFVDMAHVAGLVAAGLYPNPIPFADVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + K +E+ E K+NAAVFPG QGGP H I AV K+A ++A Sbjct: 239 LI--------LAKSNEEI----EKKLNAAVFPGAQGGPLMHVIAAKAVCFKEALEPGFKA 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A+ +GYD+VSGGTDNHL LV+L ++G+ G + L HI NK Sbjct: 287 YQQQVIENAQAMAQVFIDRGYDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGF 1388 N VP D S V G+R+GTPA+T+RGF Sbjct: 347 NAVPNDPQSPFVTSGLRIGTPAVTTRGF 374
>Q9I138:GLYA2_PSEAE Serine hydroxymethyltransferase 2 - Pseudomonas aeruginosa| Length = 418 Score = 355 bits (911), Expect = 4e-97 Identities = 192/397 (48%), Positives = 249/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ D E+ ++ E RQ +ELI SEN+ S VMQA G +TNKY+EGYPG RYYGG Sbjct: 8 LQGYDDELLAAMDAEDRRQEDHIELIASENYASKRVMQAQGGGLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L RA + F D NVQP SGS AN VY ALL D I+ + L H Sbjct: 68 CEHVDKVERLAIDRARQLFGADY----ANVQPHSGSSANAAVYLALLNAGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K+S+ + + Y LD +TGLIDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----AKVSSSGKLYNAVQYGLDTATGLIDYDEVERLAVEHKPKMIVAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R I DK A+L DMAH++GLVAAG+ P+P +ADVVTTTTHK+LRGPRG Sbjct: 179 SKTLDFPRFRAIADKVGALLFVDMAHVAGLVAAGLYPNPIPFADVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R + E K+N+AVFPG QGGP H I AV K+A ++ Sbjct: 239 LILAR------------ANEEIEKKLNSAVFPGAQGGPLMHVIAAKAVCFKEALEPGFKD 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ QV+ N+ AE +GYD+VSGGTDNHL+L++L K+G+ G + L HI NK Sbjct: 287 YQAQVIRNAKAMAEVFIGRGYDVVSGGTDNHLMLISLVKQGLTGKAADAALGAAHITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N VP D S V GIR+GTPA+T+RGF E + ++A Sbjct: 347 NAVPNDPQSPFVTSGIRIGTPAVTTRGFREGECRELA 383
>Q8PZQ0:GLYA_METMA Serine hydroxymethyltransferase - Methanosarcina mazei| (Methanosarcina frisia) Length = 412 Score = 354 bits (908), Expect = 9e-97 Identities = 193/402 (48%), Positives = 254/402 (63%), Gaps = 1/402 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +E++DPE+ + I+ E RQ L LI SEN+ S +VM+A GS+MTNKY+EGY G RYYGG Sbjct: 4 IEKIDPELFEAIKNEADRQEHKLNLIASENYASRAVMEAQGSIMTNKYAEGYSGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 +++D+AE L RA E F VNVQP SGS AN VY ++L+P D I+++DL H Sbjct: 64 CDFVDVAENLAIARAKELFGAKY----VNVQPHSGSGANMAVYFSVLQPGDTILSMDLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHLSHG +S + +PY + + T +DYD+L K A +P++IV GASAY Sbjct: 120 GGHLSHG-----SPVSFSGKLYNIVPYGVSKETEALDYDELLKLAKECKPRMIVCGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ R R+I D+ A LLAD+AHI+GLV AGV PSP YAD VTTTTHK+LRGPRG Sbjct: 175 PRVIDFKRFREIADEVGAYLLADIAHIAGLVVAGVHPSPVPYADFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI + I +N AVFPG+QGGP H I AVA K+A ++E+R Sbjct: 235 MIISKTEELAIG-------------VNKAVFPGIQGGPLMHIIAAKAVAFKEAMSEEFRQ 281 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Q+Q + N+ L KG+DIVSGGTDNHL+LVNL I G E L I ANK Sbjct: 282 DQDQTVKNAKVLCSCLKQKGFDIVSGGTDNHLMLVNLNNMNITGKDAEAALSKAGIIANK 341 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS 1430 NTVP + S V G+R+GTP+ T+RG E++ VA++ ++ Sbjct: 342 NTVPFETRSPFVTSGVRLGTPSCTTRGMKEKEMELVADYIEA 383
>Q5FNK4:GLYA_GLUOX Serine hydroxymethyltransferase - Gluconobacter oxydans| (Gluconobacter suboxydans) Length = 434 Score = 354 bits (908), Expect = 9e-97 Identities = 200/467 (42%), Positives = 275/467 (58%), Gaps = 1/467 (0%) Frame = +3 Query: 180 TEERSAVTWPKQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVM 359 +E S T + +APL+EVD E+A I+ E RQ G+ELI SEN S +VM+A GSV+ Sbjct: 2 SEHASQSTLNRFFHAPLKEVDAEVATILNEELTRQQDGIELIASENMASFAVMEAQGSVL 61 Query: 360 TNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYT 539 TNKY+EG PG RYYGG +D E L R + F + NVQP SG+ AN + Sbjct: 62 TNKYAEGLPGKRYYGGCVDVDRVENLAIDRLKKIFGAE----FANVQPHSGANANQAAFM 117 Query: 540 ALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKS 719 AL KP D ++ L L GGHL+HG + +F ++ Y + GLIDYDQ+E Sbjct: 118 ALAKPGDTVLGLSLAAGGHLTHGAAPNYS-----GKWFNSVQYGVRAEDGLIDYDQMEAL 172 Query: 720 AVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYAD 899 A +PK+IVAG+SAY R+ D+ R RKI D+ A L+ DMAH +GLVAAG+ P+P AD Sbjct: 173 AREHKPKIIVAGSSAYPRVIDFARFRKIADEVGAYLMVDMAHFAGLVAAGLYPNPVPMAD 232 Query: 900 VVTTTTHKSLRGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTIT 1079 + T+TTHK+LRGPRG +I D K+N+AVFPGLQGGP H I Sbjct: 233 ITTSTTHKTLRGPRGGIILTNNP-------------DLAKKVNSAVFPGLQGGPLMHVIA 279 Query: 1080 GLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDG 1259 G AVA +A + E++AYQ++V++N+ A+ L ++G+DIV+GGTD+HL+LV+L+ K + G Sbjct: 280 GKAVAFGEALSDEFKAYQKRVLANARALADELQNRGFDIVTGGTDSHLILVDLRPKKVTG 339 Query: 1260 SRVEKVLENVHIAANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXX 1436 E +LE I ANKN +P D V GIR+G+PA T+RGF E +F +V D Sbjct: 340 KLAEAILERAGITANKNAIPFDPEKPFVTSGIRLGSPAATARGFGEAEFREVGRMIDEV- 398 Query: 1437 XXXXXXXXXXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 A L+ D N +A A++ +V+ ++FP Sbjct: 399 -----------------LTAALEED-NAEAVTARVHEEVKALCRRFP 427
>O85718:GLYA_ACIRA Serine hydroxymethyltransferase - Acinetobacter radioresistens| Length = 417 Score = 354 bits (908), Expect = 9e-97 Identities = 193/402 (48%), Positives = 255/402 (63%), Gaps = 1/402 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N + E DPE+A I E ARQ +ELI SEN+ S +VM+A GS +TNKY+EGYPG RY Sbjct: 4 NISIAEFDPELAQAITNEDARQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRY 63 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG EY+D+ E L RA E F D NVQP +GS AN VY ALL P D ++ + Sbjct: 64 YGGCEYVDIIEQLAIDRAKELFGADY----ANVQPHAGSQANSAVYLALLNPGDTVLGMS 119 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG K+S + + Y L+ TG IDY+++E+ A+ +P++IVAG Sbjct: 120 LAHGGHLTHG-----AKVSFSGKTYNAIQYGLNPETGEIDYEEVERLALEHKPRMIVAGF 174 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY+++ D+ R R I DK A L DMAH++GLVAAGV P+P + ADV TTTTHK+LRGP Sbjct: 175 SAYSQIVDWQRFRDIADKIGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTLRGP 234 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 R +I + K +E+ E K+ +AVFPG QGGP H + A+ K+A E Sbjct: 235 RSGLI--------LAKANEEI----EKKLQSAVFPGNQGGPLVHAVAAKAICFKEAMAPE 282 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 Y+AYQ+QV+ N+ AE L +GYD+VSGGT NHL L++L K+ I G + L HI Sbjct: 283 YKAYQQQVVKNAQAMAEVLIERGYDVVSGGTKNHLFLLSLIKQDITGKDADAWLGAAHIT 342 Query: 1299 ANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NKN+VP D S V GIR+GTPA+T+RGF E + +A + Sbjct: 343 VNKNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRDLASW 384
>Q88Q27:GLYA2_PSEPK Serine hydroxymethyltransferase 2 - Pseudomonas putida (strain| KT2440) Length = 417 Score = 354 bits (908), Expect = 9e-97 Identities = 198/454 (43%), Positives = 268/454 (59%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ + ++ E RQ + +ELI SEN+TS +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 8 IAKYDAELFEAMQQEALRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP +GS AN VY ALL D I+ + L H Sbjct: 68 CEYVDVVEQLAIDRAKELFGADY----ANVQPHAGSQANAAVYLALLSAGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG +S+ + + Y +D GLIDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----ASVSSSGKLYNAIQYGID-GNGLIDYDEVERLAVEHKPKMIVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ R R I DK A L DMAH++GLVAAGV P+P +ADVVTTTTHK+LRGPRG Sbjct: 178 SQVLDFARFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R D E K+N+AVFPG QGGP H I A+ K+A E++A Sbjct: 238 LILARANA------------DIEKKLNSAVFPGAQGGPLEHVIAAKAICFKEALQPEFKA 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +G+D+VSGGT NHL L++L K+ I G + L I NK Sbjct: 286 YQQQVVKNAQAMASVFIERGFDVVSGGTQNHLFLLSLIKQEISGKDADAALGKAFITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R GTPA+T+RGF E + ++A Sbjct: 346 NSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELA----------------------- 382 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 ++ + +D N +A I +R V+ K+ P G Sbjct: 383 GWICDILADLNNEAVIDAVREKVKAICKKLPVYG 416
>Q3AN03:GLYA_SYNSC Serine hydroxymethyltransferase - Synechococcus sp. (strain CC9605)| Length = 431 Score = 353 bits (907), Expect = 1e-96 Identities = 196/404 (48%), Positives = 257/404 (63%), Gaps = 1/404 (0%) Frame = +3 Query: 210 KQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPG 389 + ++A L + DP+IA I E+ RQ LELI SENF S +VMQA GSV+TNKY+EG P Sbjct: 7 RAIDADLAQSDPDIAAFINQERQRQETHLELIASENFASRAVMQAQGSVLTNKYAEGLPS 66 Query: 390 ARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIM 569 RYYGG E++D E L +RA + F W NVQP SG+ ANF V+ ALL+P D IM Sbjct: 67 KRYYGGCEHVDAIEELAIERAKQLFGA---AWA-NVQPHSGAQANFAVFLALLQPGDTIM 122 Query: 570 ALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIV 749 LDL HGGHL+HG ++ +F + Y +D+ T +D + + + A+ +PKLIV Sbjct: 123 GLDLSHGGHLTHG-----SPVNVSGKWFNVVQYGVDKETQRLDMEAIRQLALEHKPKLIV 177 Query: 750 AGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSL 929 G SAY R D+ R I D+ A LLADMAHI+GLVAAGV PSP + DVVTTTTHK+L Sbjct: 178 CGYSAYPRTIDFAAFRAIADEVGAYLLADMAHIAGLVAAGVHPSPVPHCDVVTTTTHKTL 237 Query: 930 RGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQAT 1109 RGPRG +I R +F K + AVFPG QGGP H I AVA +A Sbjct: 238 RGPRGGLILCRDA-------------EFAKKFDKAVFPGSQGGPLEHVIAAKAVAFGEAL 284 Query: 1110 TQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENV 1289 ++AY +QV++N+A AE L ++G D+VSGGTDNH+VL++L+ G+ G + ++ +V Sbjct: 285 QPSFKAYSQQVVANAAALAEQLIARGIDVVSGGTDNHVVLLDLRSIGMTGKVADLLVSDV 344 Query: 1290 HIAANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 HI ANKNTVP D S V G+R GT ALT+RGF + F +VA+ Sbjct: 345 HITANKNTVPFDPESPFVTSGLRFGTAALTTRGFDSQAFREVAD 388
>Q8PPE3:GLYA_XANAC Serine hydroxymethyltransferase - Xanthomonas axonopodis pv. citri| Length = 417 Score = 352 bits (903), Expect = 3e-96 Identities = 198/454 (43%), Positives = 270/454 (59%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE DPE+A I E RQ +ELI SEN+ S VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 LETYDPELAKAIAAEAGRQEDHVELIASENYCSPLVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L +R + F D NVQP SGS AN VY ALL+P D I+ + L H Sbjct: 68 CEFVDIAEQLAIERIKQVFGADY----ANVQPHSGSQANQAVYLALLQPGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K++ F + Y ++E GLIDYD++++ A +PK++VAG SAY Sbjct: 124 GGHLTHG-----AKVNVSGKLFNAVQYGVNEQ-GLIDYDEVQRLATEHKPKMVVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R I D A L DMAHI+GLVAAGV PSP E+A VVT+TTHK+LRGPRG Sbjct: 178 SQKIDWARFRAIADSVGAYLFVDMAHIAGLVAAGVYPSPMEHAHVVTSTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + +E+ K K+ + VFPG+QGGP H I AVA K+A ++ Sbjct: 238 IIVAKGASEELQK-----------KLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +L ++GY IVSGGT+NHL+LV++ + + G E L HI NK Sbjct: 287 YQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R+GTPA+T+RG+ E+D L Sbjct: 347 NSVPNDPRSPFVTSGLRLGTPAITTRGYQEQD-----------------------SIDLA 383 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 +++A + +A +AK+R V K++P G Sbjct: 384 NWIADVLDAPTDEAVLAKVRDAVTAQCKRYPVYG 417
>Q3APN5:GLYA_CHLCH Serine hydroxymethyltransferase - Chlorobium chlorochromatii (strain| CaD3) Length = 438 Score = 352 bits (903), Expect = 3e-96 Identities = 193/407 (47%), Positives = 255/407 (62%), Gaps = 7/407 (1%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L++ D E+ I E RQ + LELI SENFTS +VMQA GSVMTNKY+EGYPG RYYGG Sbjct: 6 LQKQDAEVFASIANETKRQTETLELIASENFTSRAVMQACGSVMTNKYAEGYPGKRYYGG 65 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L + RA + F + VNVQP SGS AN V ++LKP D+IM LDL H Sbjct: 66 CEFVDVAENLARDRAKKLFGCEY----VNVQPHSGSSANMAVLFSVLKPGDKIMGLDLSH 121 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ FE Y +D TG ID +++E+ A+ RPKLI+ GASAY Sbjct: 122 GGHLTHG-----SSVNFSGQMFEAHSYGVDRETGCIDMNKVEEMAMQVRPKLIIGGASAY 176 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ +D+ R I DK A+L+AD+AH +GL+AAG++P+P ++ VTTTTHK+LRGPRG Sbjct: 177 SQGFDFKAFRAIADKVGALLMADIAHPAGLIAAGLLPNPLQHCHFVTTTTHKTLRGPRGG 236 Query: 948 MIFFRK------GVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQAT 1109 MI G+ K G VK + ++A V PG+QGGP H I G AVA +A Sbjct: 237 MIMMGSDFENPLGITIKTKTGSRVKM-MSEVMDAEVMPGIQGGPLMHIIAGKAVAFGEAL 295 Query: 1110 TQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENV 1289 ++ Y QVM N++ A GY IVSGGT NHL+L++L+ K + G E +L Sbjct: 296 QPAFKEYAAQVMKNASTMASRFMELGYTIVSGGTKNHLMLLDLRNKNVTGKEAENLLHEA 355 Query: 1290 HIAANKNTVP-GDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 I NKN VP D S V GIR+GTPA+T+RG E + ++AE D Sbjct: 356 GITVNKNMVPFDDKSPFVTSGIRIGTPAMTTRGMKEAESRRIAELID 402
>Q3K6J0:GLYA2_PSEPF Serine hydroxymethyltransferase 2 - Pseudomonas fluorescens (strain| PfO-1) Length = 417 Score = 352 bits (903), Expect = 3e-96 Identities = 197/454 (43%), Positives = 269/454 (59%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D ++ +E E RQ + +ELI SEN+TS +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 8 IAKYDADLFAAMEQEAQRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP +GS AN VY ALL D I+ + L H Sbjct: 68 CEYVDVVEQLAIDRAKELFGADY----ANVQPHAGSQANAAVYLALLSAGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG +S+ + + Y +D + GLIDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----ASVSSSGKLYNAIQYGID-ANGLIDYDEVERLAVEHKPKMIVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ R R I DK A L DMAH++GLVAAGV P+P +ADVVTTTTHK+LRGPRG Sbjct: 178 SQILDFPRFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + D E K+N+AVFPG QGGP H I A+ K+A E++A Sbjct: 238 LILAKANA------------DIEKKLNSAVFPGAQGGPLEHVIAAKAICFKEALQPEFKA 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +G+D+VSGGT+NHL L++L K+ I G + L I NK Sbjct: 286 YQQQVVKNAQAMAGVFIERGFDVVSGGTENHLFLLSLIKQEISGKDADAALGKAFITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R GTPA+T+RGF E + ++A Sbjct: 346 NSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELA----------------------- 382 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 ++ + +D N +A I +R V+ K+ P G Sbjct: 383 GWICDILADLNNEAVIDAVREKVKAICKKLPVYG 416
>Q67N41:GLYA_SYMTH Serine hydroxymethyltransferase - Symbiobacterium thermophilum| Length = 412 Score = 351 bits (901), Expect = 6e-96 Identities = 193/451 (42%), Positives = 269/451 (59%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ DPE+ I+ E RQ + +ELI SENF +V++A G+V+TNKY+EGYPG RYYGG Sbjct: 4 LKRYDPEVFAAIQQEVERQQRNIELIASENFVPKAVLEAAGTVLTNKYAEGYPGRRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E + ++R AF + VNVQP SG+ AN VY A L+P D ++ ++L Sbjct: 64 CEYVDIVENIARERLKAAFGAEH----VNVQPHSGANANTAVYFAFLQPGDTVLGMNLAQ 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY LD T I+ DQ+ + A RPKLIVAG SAY Sbjct: 120 GGHLTHG-----SPVNFSGRTYNFVPYGLDPETERINMDQVAELARQHRPKLIVAGYSAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ R R+I ++ A+L+ DMAH +GL A G P+P E+A VVTTTTHK+LRGPRG Sbjct: 175 PRVLDFKRFREIAEEVGAILMVDMAHFAGLAATGYYPNPVEHAHVVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 I +K +F +I+ AVFPG+QGGP H I AVA KQ + +YRA Sbjct: 235 AILCKK--------------EFAKEIDKAVFPGMQGGPLMHIIAAKAVAFKQLSDPDYRA 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV+ N+ A++L +GY +V+GGTDNHL+LV+L+ KGI G E +L+ V I NK Sbjct: 281 YCGQVVKNAKALAQALLERGYRLVTGGTDNHLMLVDLRPKGITGRDAEHLLDRVSITVNK 340 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D MV GIR+GTPA+T+RG E + ++A+ D Sbjct: 341 NAIPNDPEKPMVTSGIRIGTPAMTTRGMKEAEMVQIADLIDRAI---------------- 384 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 + N +AE+ ++R +V E +FP Sbjct: 385 -------THRNDEAELDRIRAEVHELTARFP 408
>Q607U4:GLYA_METCA Serine hydroxymethyltransferase - Methylococcus capsulatus| Length = 418 Score = 351 bits (901), Expect = 6e-96 Identities = 195/388 (50%), Positives = 250/388 (64%), Gaps = 2/388 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D E+ I+ E+ RQ +ELI SEN+ S V+QA G+V+TNKY+EGYPG RYYGG EY+ Sbjct: 12 DDELWAAIQEEERRQEDHIELIASENYASPRVLQAQGTVLTNKYAEGYPGKRYYGGCEYV 71 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ ETL +RA F D NVQP SGS AN VY ALLKP D ++ + L HGGHL Sbjct: 72 DIVETLAIERAKRLFGADY----ANVQPHSGSQANAAVYMALLKPGDTVLGMSLAHGGHL 127 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG K++ + + Y L+ TG IDYDQ+++ A RPK+IVAG SAY+++ Sbjct: 128 THG-----AKVNFSGKIYNAVQYGLNPETGEIDYDQVDELAREHRPKMIVAGFSAYSQVV 182 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R R I D A L+ DMAH++GL+AAG+ PSP + ADV TTTTHK+LRGPRG +I Sbjct: 183 DWQRFRAIADSVGAWLMVDMAHVAGLIAAGLYPSPVQIADVTTTTTHKTLRGPRGGLI-L 241 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 K E+ KQ +N+ VFPG+QGGP H I AVALK+A ++R YQ Sbjct: 242 AKANPEVEKQ-----------LNSLVFPGIQGGPLMHVIAAKAVALKEALQPDFRHYQSA 290 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 VM N+ A++ +GY IVSGGT NHL LV+L +KG+ G E+VL HI NKN VP Sbjct: 291 VMENADAMAKTFIERGYRIVSGGTRNHLFLVDLIQKGLTGKLAEEVLGRAHITVNKNAVP 350 Query: 1320 GD-VSAMVPGGIRMGTPALTSRGF-VEE 1397 D S V GIR+GTPA+T+RGF VEE Sbjct: 351 NDPQSPFVTSGIRVGTPAVTTRGFGVEE 378
>Q5KUI2:GLYA_GEOKA Serine hydroxymethyltransferase - Geobacillus kaustophilus| Length = 412 Score = 351 bits (901), Expect = 6e-96 Identities = 187/397 (47%), Positives = 260/397 (65%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L + DP++ IE E+ RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 4 LPQQDPQVFAAIEQERKRQHAKIELIASENFVSRAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L ++RA + F + VNVQP SG+ AN VY +L+ D ++ ++L H Sbjct: 64 CEYVDIVEDLARERAKQLFGAEH----VNVQPHSGAQANMAVYFTVLEHGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ I + + Y +D T +IDYD + + A L RPKLIVAGASAY Sbjct: 120 GGHLTHG-----SPVNFSGIQYNFVEYGVDPETHVIDYDDVREKARLHRPKLIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ + R+I D+ A L+ DMAHI+GLVAAGV P+P YA VTTTTHK+LRGPRG Sbjct: 175 PRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAGVHPNPVPYAHFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI ++ F +I+ A+FPG+QGGP H I AVAL +A +++ Sbjct: 235 MILCQE--------------QFAKQIDKAIFPGIQGGPLMHVIAAKAVALGEALQDDFKV 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y ++V+ N+ R A +L ++G+ ++SGGTDNHL+LV+L+ + + G EKVL+ V I NK Sbjct: 281 YAKRVVENAKRLAAALQNEGFTLISGGTDNHLLLVDLRPQQLTGKTAEKVLDEVGITVNK 340 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 NT+P D S V GIR+GT A+T+RGF E+ ++A Sbjct: 341 NTIPYDPESPFVTSGIRIGTAAVTTRGFGLEEMDEIA 377
>Q8PCN4:GLYA_XANCP Serine hydroxymethyltransferase - Xanthomonas campestris pv.| campestris Length = 417 Score = 351 bits (900), Expect = 7e-96 Identities = 199/454 (43%), Positives = 270/454 (59%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE DPE+A I E RQ +ELI SEN+ S VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 LETYDPELAKAIAAEAGRQEDHVELIASENYCSPLVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L R + F D NVQP SGS AN VY ALL+P D I+ + L H Sbjct: 68 CEFVDIAEQLAIDRIKQVFGADY----ANVQPHSGSQANQAVYLALLQPGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K++A F + Y ++E GLIDYD++++ A +PK+++AG SAY Sbjct: 124 GGHLTHG-----AKVNASGKLFNAVQYGVNEQ-GLIDYDEVQRLATEHKPKMVIAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R I D A L DMAH++GLVAAGV PSP ++A VVT+TTHK+LRGPRG Sbjct: 178 SQKIDWARFRAIADSVGAYLFVDMAHVAGLVAAGVYPSPMDHAHVVTSTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I KG E D K+ + VFPG+QGGP H I AVA K+A E++ Sbjct: 238 II-LAKGAGE----------DLVKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +L ++GY IVSGGT+NHL+LV++ + + G E L HI NK Sbjct: 287 YQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R+GTPA+T+RG+ E+D +A Sbjct: 347 NSVPNDPRSPFVTSGLRLGTPAITTRGYQEQDCVDLA----------------------- 383 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 +++A + A +AK+R V K++P G Sbjct: 384 NWIADVLDAPADDAVLAKVRDAVTAQCKKYPVYG 417
>Q4UQT6:GLYA_XANC8 Serine hydroxymethyltransferase - Xanthomonas campestris pv.| campestris (strain 8004) Length = 417 Score = 351 bits (900), Expect = 7e-96 Identities = 199/454 (43%), Positives = 270/454 (59%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE DPE+A I E RQ +ELI SEN+ S VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 LETYDPELAKAIAAEAGRQEDHVELIASENYCSPLVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L R + F D NVQP SGS AN VY ALL+P D I+ + L H Sbjct: 68 CEFVDIAEQLAIDRIKQVFGADY----ANVQPHSGSQANQAVYLALLQPGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K++A F + Y ++E GLIDYD++++ A +PK+++AG SAY Sbjct: 124 GGHLTHG-----AKVNASGKLFNAVQYGVNEQ-GLIDYDEVQRLATEHKPKMVIAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R I D A L DMAH++GLVAAGV PSP ++A VVT+TTHK+LRGPRG Sbjct: 178 SQKIDWARFRAIADSVGAYLFVDMAHVAGLVAAGVYPSPMDHAHVVTSTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I KG E D K+ + VFPG+QGGP H I AVA K+A E++ Sbjct: 238 II-LAKGAGE----------DLVKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +L ++GY IVSGGT+NHL+LV++ + + G E L HI NK Sbjct: 287 YQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R+GTPA+T+RG+ E+D +A Sbjct: 347 NSVPNDPRSPFVTSGLRLGTPAITTRGYQEQDCVDLA----------------------- 383 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 +++A + A +AK+R V K++P G Sbjct: 384 NWIADVLDAPADDAVLAKVRDAVTAQCKKYPVYG 417
>Q3BXI8:GLYA_XANC5 Serine hydroxymethyltransferase - Xanthomonas campestris pv.| vesicatoria (strain 85-10) Length = 417 Score = 350 bits (899), Expect = 9e-96 Identities = 198/454 (43%), Positives = 269/454 (59%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE DPE+A I E RQ +ELI SEN+ S VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 LETYDPELAKAIAAEAGRQEDHVELIASENYCSPLVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L R + F D NVQP SGS AN VY ALL+P D I+ + L H Sbjct: 68 CEFVDIAEQLAIDRIKQVFGADY----ANVQPHSGSQANQAVYLALLQPGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K++ F + Y ++E GLIDYD++++ A +PK++VAG SAY Sbjct: 124 GGHLTHG-----AKVNVSGKLFYAVQYGVNEQ-GLIDYDEVQRLATEHKPKMVVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R I D A L DMAHI+GLVAAGV PSP E+A VVT+TTHK+LRGPRG Sbjct: 178 SQKIDWARFRAIADSVGAYLFVDMAHIAGLVAAGVYPSPMEHAHVVTSTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + +E+ K K+ + VFPG+QGGP H I AVA K+A ++ Sbjct: 238 IIVAKGASEELQK-----------KLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +L ++GY IVSGGT+NHL+LV++ + + G E L HI NK Sbjct: 287 YQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R+GTPA+T+RG+ E+D L Sbjct: 347 NSVPNDPRSPFVTSGLRLGTPAITTRGYQEQD-----------------------SIDLA 383 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 +++A + +A +AK+R V K++P G Sbjct: 384 NWIADVLDAPTDEAVLAKVRDAVTAQCKRYPVYG 417
>Q64U78:GLYA_BACFR Serine hydroxymethyltransferase - Bacteroides fragilis| Length = 426 Score = 350 bits (899), Expect = 9e-96 Identities = 194/405 (47%), Positives = 259/405 (63%), Gaps = 8/405 (1%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D I DIIE E RQ KG+ELI SENF S VM+A+GS +TNKY+EGYPG RYYGG E + Sbjct: 4 DDLIFDIIEKEHQRQLKGIELIASENFVSDQVMEAMGSCLTNKYAEGYPGKRYYGGCEVV 63 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D +E + R E F + W NVQP SG+ AN V+ A+L P D+ M L+L HGGHL Sbjct: 64 DQSEQIAIDRLKEIFGAE---WA-NVQPHSGAQANAAVFLAVLNPGDKFMGLNLAHGGHL 119 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 SHG +T I + Y L + TG +DYDQ+E+ A+ +PK+I+ G SAY+R + Sbjct: 120 SHGSLVNTS-----GIIYTPCEYNLKQETGRVDYDQMEEVALREKPKMIIGGGSAYSREW 174 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 DY RMR+I DK A+L+ DMAH +GL+AAG++ +P +YA +VT+TTHK+LRGPRG +I Sbjct: 175 DYKRMREIADKVGAILMIDMAHPAGLIAAGLLDNPVKYAHIVTSTTHKTLRGPRGGVIMM 234 Query: 960 RKGVKEINKQGK-----EVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 K N GK E+K +++AVFPG+QGGP H I AVA + EY+ Sbjct: 235 GKDFP--NPWGKKTPKGEIKM-MSQLLDSAVFPGIQGGPLEHVIAAKAVAFGECLQPEYK 291 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK--GIDGSRVEKVLENVHIA 1298 YQ+QV N+A A++L +G+ IVSGGTDNH +LV+L+ K + G EK L + I Sbjct: 292 EYQKQVQKNAAVLAQALIDRGFTIVSGGTDNHSMLVDLRSKYPTLTGKVAEKALVSADIT 351 Query: 1299 ANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS 1430 NKN VP D SA GIR+GTPA+T+RG E+ ++AE ++ Sbjct: 352 VNKNMVPFDSRSAFQTSGIRLGTPAITTRGAKEDLMLEIAEMIET 396
>Q5LD58:GLYA_BACFN Serine hydroxymethyltransferase - Bacteroides fragilis (strain ATCC| 25285 / NCTC 9343) Length = 426 Score = 350 bits (899), Expect = 9e-96 Identities = 194/405 (47%), Positives = 259/405 (63%), Gaps = 8/405 (1%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D I DIIE E RQ KG+ELI SENF S VM+A+GS +TNKY+EGYPG RYYGG E + Sbjct: 4 DDLIFDIIEKEHQRQLKGIELIASENFVSDQVMEAMGSCLTNKYAEGYPGKRYYGGCEVV 63 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D +E + R E F + W NVQP SG+ AN V+ A+L P D+ M L+L HGGHL Sbjct: 64 DQSEQIAIDRLKEIFGAE---WA-NVQPHSGAQANAAVFLAVLNPGDKFMGLNLAHGGHL 119 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 SHG +T I + Y L + TG +DYDQ+E+ A+ +PK+I+ G SAY+R + Sbjct: 120 SHGSLVNTS-----GIIYTPCEYNLKQETGRVDYDQMEEVALREKPKMIIGGGSAYSREW 174 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 DY RMR+I DK A+L+ DMAH +GL+AAG++ +P +YA +VT+TTHK+LRGPRG +I Sbjct: 175 DYKRMREIADKVGAILMIDMAHPAGLIAAGLLDNPVKYAHIVTSTTHKTLRGPRGGVIMM 234 Query: 960 RKGVKEINKQGK-----EVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 K N GK E+K +++AVFPG+QGGP H I AVA + EY+ Sbjct: 235 GKDFP--NPWGKKTPKGEIKM-MSQLLDSAVFPGIQGGPLEHVIAAKAVAFGECLQPEYK 291 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK--GIDGSRVEKVLENVHIA 1298 YQ+QV N+A A++L +G+ IVSGGTDNH +LV+L+ K + G EK L + I Sbjct: 292 EYQKQVQKNAAVLAQALIDRGFTIVSGGTDNHSMLVDLRSKYPTLTGKVAEKALVSADIT 351 Query: 1299 ANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS 1430 NKN VP D SA GIR+GTPA+T+RG E+ ++AE ++ Sbjct: 352 VNKNMVPFDSRSAFQTSGIRLGTPAITTRGAKEDLMLEIAEMIET 396
>O66776:GLYA_AQUAE Serine hydroxymethyltransferase - Aquifex aeolicus| Length = 428 Score = 350 bits (899), Expect = 9e-96 Identities = 195/451 (43%), Positives = 269/451 (59%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L + DPE+ D + E RQ+ LE+I SENFTSL+VM+A GSV+TNKY+EG PG RYYGG Sbjct: 4 LLKTDPEVFDAVVKEYERQFYNLEMIASENFTSLAVMEATGSVLTNKYAEGLPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L +RA + F + NVQP SGS AN VY A+L P D IM +DL H Sbjct: 64 CEYVDVVENLAIERAKKLFGAEH----ANVQPHSGSQANMAVYFAVLNPGDTIMGMDLAH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K++ + + Y ++ T LIDYDQL K A +PKLIV GASAY Sbjct: 120 GGHLTHG-----AKVNFSGKLYNVIHYGVNPETELIDYDQLYKLAKEHKPKLIVGGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R++D+ +MR+I D+ A+ + DMAH +GL+A GV P+P YA VT+TTHK+LRGPR Sbjct: 175 PRVFDWAKMREIADEVGALFMVDMAHYAGLIAGGVYPNPVPYAQFVTSTTHKTLRGPRSG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 I K ++ ++ +VFPG+QGGP H I AVA K+A ++E++ Sbjct: 235 FILTTK--------------EYAKAVDKSVFPGIQGGPLMHVIAAKAVAFKEAMSEEFKE 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +QV+ N+ AE L G+ IV+GGTD+H+VLV+L+ K I G EK LE I NK Sbjct: 281 YAKQVVENARVLAEELKKYGFKIVTGGTDSHIVLVDLRNKNIIGKDAEKALEKAGITVNK 340 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N VP D + GIR+GT ALT+RG E++ K+A + + Sbjct: 341 NAVPFDPLPPTKTSGIRIGTAALTTRGMKEDEMRKIAGW-------------------IN 381 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 + ++ + + IQ ++R +V E + FP Sbjct: 382 EVLSNMDDEKTIQ----RVRQEVRELCETFP 408
>Q8A9S7:GLYA_BACTN Serine hydroxymethyltransferase - Bacteroides thetaiotaomicron| Length = 426 Score = 350 bits (898), Expect = 1e-95 Identities = 203/454 (44%), Positives = 274/454 (60%), Gaps = 8/454 (1%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D I DIIE E RQ KG+ELI SENF S VMQA+GS +TNKY+EGYPG RYYGG E + Sbjct: 4 DDLIFDIIEKEHQRQLKGIELIASENFVSDQVMQAMGSCLTNKYAEGYPGKRYYGGCEVV 63 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D +E + R E F + W NVQP SG+ AN V+ A+L P D+ M L+L HGGHL Sbjct: 64 DQSEQIAIDRLKEIFGAE---WA-NVQPHSGAQANAAVFLAVLNPGDKFMGLNLAHGGHL 119 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 SHG +T I + Y L++ TG +DYDQ+E+ A+ +PK+I+ G SAY+R + Sbjct: 120 SHGSLVNTS-----GIIYTPCEYNLNQETGRVDYDQMEEVALREKPKMIIGGGSAYSREW 174 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 DY RMR+I DK A+L+ DMAH +GL+AAG++ +P +YA +VT+TTHK+LRGPRG +I Sbjct: 175 DYKRMREIADKVGAILMIDMAHPAGLIAAGLLENPVKYAHIVTSTTHKTLRGPRGGVIMM 234 Query: 960 RKGVKEINKQGK-----EVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 K N GK E+K +++AVFPG+QGGP H I AVA + EY+ Sbjct: 235 GKDFP--NPWGKKTPKGEIKM-MSQLLDSAVFPGVQGGPLEHVIAAKAVAFGEILQPEYK 291 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK--GIDGSRVEKVLENVHIA 1298 Y +QV N+A A++L +G+ IVSGGTDNH +LV+L+ K + G EK L + I Sbjct: 292 EYAKQVQKNAAILAQALIDRGFTIVSGGTDNHSMLVDLRSKYPDLTGKVAEKALVSADIT 351 Query: 1299 ANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGT 1475 NKN VP D SA GIR+GTPA+T+RG E+ ++AE Sbjct: 352 VNKNMVPFDSRSAFQTSGIRLGTPAITTRGAKEDLMIEIAE------------------- 392 Query: 1476 KLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 + T+ S+ + IA++R V E K++P Sbjct: 393 ----MIETVLSNVENEEVIAQVRARVNETMKKYP 422
>Q4ZM83:GLYA2_PSEU2 Serine hydroxymethyltransferase 2 - Pseudomonas syringae pv. syringae| (strain B728a) Length = 417 Score = 350 bits (898), Expect = 1e-95 Identities = 186/388 (47%), Positives = 246/388 (63%), Gaps = 1/388 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++ D + + E+ RQ +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IQGYDDALLSAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L +RA + F D NVQP SGS AN VY ALL+ D ++ + L H Sbjct: 68 CEHVDKVEQLAIERARQLFGADY----ANVQPHSGSQANAAVYLALLQAGDTVLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K+S + + Y +D +TGLIDYD++E+ AV +PK+I+AG SAY Sbjct: 124 GGHLTHG-----AKVSFSGKLYNAVQYGIDTATGLIDYDEVERIAVECQPKMIIAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R I DK A L DMAH++GLVAAG+ P+P YADVVTTTTHK+LRGPRG Sbjct: 179 SKTLDFPRFRAIADKVGAYLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R + E K N+AVFPG QGGP H I AV K+A ++A Sbjct: 239 LILAR------------ANEELEKKFNSAVFPGGQGGPLMHVIAAKAVCFKEAMEPGFKA 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A+ +G+D+VSGGTDNHL LV+L ++G+ G + L HI NK Sbjct: 287 YQQQVIDNAQAMAQVFIDRGFDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGF 1388 N+VP D S V G+R+GTPA+T+RGF Sbjct: 347 NSVPNDPQSPFVTSGLRIGTPAVTTRGF 374
>Q48CP3:GLYA2_PSE14 Serine hydroxymethyltransferase 2 - Pseudomonas syringae pv.| phaseolicola (strain 1448A / Race 6) Length = 417 Score = 350 bits (897), Expect = 2e-95 Identities = 185/388 (47%), Positives = 247/388 (63%), Gaps = 1/388 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++ D + + E+ RQ +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IQGYDDALLSAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L +RA + F D NVQP SGS AN VY ALL+ D ++ + L H Sbjct: 68 CEHVDKVEQLAIERAKQLFGADY----ANVQPHSGSQANAAVYLALLQAGDTVLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K+S + + Y +D +TGLIDYD++E+ AV +PK+I+AG SAY Sbjct: 124 GGHLTHG-----AKVSFSGKLYNAVQYGIDTTTGLIDYDEVERIAVECQPKMIIAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R+I DK A L DMAH++GLVAAG+ P+P YADVVTTTTHK+LRGPRG Sbjct: 179 SKTLDFPRFREIADKVGAYLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + + E K N+AVFPG QGGP H I AV K+A ++A Sbjct: 239 LIL------------AKANEELEKKFNSAVFPGGQGGPLMHVIAAKAVCFKEAMEPGFKA 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A+ +G+D+VSGGTDNHL LV+L ++G+ G + L HI NK Sbjct: 287 YQQQVIDNAQAMAQVFIDRGFDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGF 1388 N+VP D S V G+R+GTPA+T+RGF Sbjct: 347 NSVPNDPQSPFVTSGLRIGTPAVTTRGF 374
>Q2S4G9:GLYA_SALRD Serine hydroxymethyltransferase - Salinibacter ruber (strain DSM| 13855) Length = 432 Score = 349 bits (896), Expect = 2e-95 Identities = 193/406 (47%), Positives = 250/406 (61%), Gaps = 6/406 (1%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L DPEI D+I+ E RQ GLELI SENF S +VM+A+G+ +TNKY+EG PG RYYGG Sbjct: 4 LRNQDPEIHDVIQKEVQRQNDGLELIASENFASRAVMEAMGTALTNKYAEGLPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E +D AE L ++RA E ++ D W VNVQP +G+ AN VY LL P D + LDL H Sbjct: 64 CEVVDRAEELARERAKELYDCD---W-VNVQPHAGAQANSAVYLTLLDPGDTFLGLDLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ I +E Y ++E TG ID +++ A +PK+I GASAY Sbjct: 120 GGHLTHG-----SPVNFSGILYEAEYYGVEEETGRIDMNRVRDRAKEVQPKMISIGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R +DY R+I D+ A L DMAH +GL+A GV+ P + VVTTTTHK+LRGPRG Sbjct: 175 PRDFDYEAFREIADEVGAFLWMDMAHTAGLIAGGVLNDPMPHTHVVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDK-----INAAVFPGLQGGPHNHTITGLAVALKQATT 1112 MI G N GK + K +++AVFPG QGGP H I AV K+A Sbjct: 235 MILL--GDDYENPMGKTARKSGRTKMMSELLDSAVFPGTQGGPLMHVIAAKAVGFKEALK 292 Query: 1113 QEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVH 1292 + Y +QV+ N+ L +GYD+VS GTDNHLVL++L+ KG+ G E+ LE Sbjct: 293 PSFAEYTQQVVDNAQAMGAELRERGYDLVSDGTDNHLVLIDLRNKGLTGKEAEQALEAAG 352 Query: 1293 IAANKNTVP-GDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 I ANKN VP D S V G+R+GTPA+T+RGF ++FA VAE D Sbjct: 353 ITANKNMVPFDDKSPFVTSGLRLGTPAMTTRGFGPDEFAHVAEMID 398
>Q7U9J7:GLYA_SYNPX Serine hydroxymethyltransferase - Synechococcus sp. (strain WH8102)| Length = 429 Score = 349 bits (895), Expect = 3e-95 Identities = 196/402 (48%), Positives = 251/402 (62%), Gaps = 1/402 (0%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 +N L DP IA +IE E+ RQ LELI SENF S +VM A GSV+TNKY+EG P R Sbjct: 9 INKGLAAADPAIAALIEKEQQRQETHLELIASENFASRAVMDAQGSVLTNKYAEGLPSKR 68 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 YYGG E++D E L +RA E F W NVQP SG+ ANF V+ ALL+P D IM L Sbjct: 69 YYGGCEHVDAIEELAIERAKELFGA---AWA-NVQPHSGAQANFAVFLALLQPGDTIMGL 124 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 DL HGGHL+HG ++ +F + Y +D T +D + + + A+ +PKLIV G Sbjct: 125 DLSHGGHLTHG-----SPVNVSGKWFNVVQYGVDRETQRLDMEAIRQLALEHKPKLIVCG 179 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 SAY R D+ R I D+ A LLADMAHI+GLVAAGV PSP + DVVTTTTHK+LRG Sbjct: 180 FSAYPRTIDFAAFRAIADEVGAFLLADMAHIAGLVAAGVHPSPVPHCDVVTTTTHKTLRG 239 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG +I R DF K + AVFPG QGGP H I AVA +A Sbjct: 240 PRGGLILCRDA-------------DFAKKFDKAVFPGSQGGPLEHVIAAKAVAFGEALQP 286 Query: 1116 EYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHI 1295 ++ Y + V++N+A AE L ++G D+VSGGTDNH+VL++L+ G+ G + ++ +VHI Sbjct: 287 AFKTYSQHVVANAAALAERLIARGIDVVSGGTDNHVVLLDLRSVGMTGKVADLLVSDVHI 346 Query: 1296 AANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 ANKNTVP D S V G+R+GT ALT+RGF F +VA+ Sbjct: 347 TANKNTVPFDPESPFVTSGLRLGTAALTTRGFDAGAFREVAD 388
>P0A2E1:GLYA_SALTY Serine hydroxymethyltransferase - Salmonella typhimurium| Length = 417 Score = 349 bits (895), Expect = 3e-95 Identities = 188/397 (47%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L Sbjct: 68 CEYVDVVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQ 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DES G IDYD++ K A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGIDES-GKIDYDEMAKLAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GL+AAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFP QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGDEELYK-----------KLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEFKV 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E ++GY +VSGGT+NHL L++L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+G+PA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELA 383
>P0A2E2:GLYA_SALTI Serine hydroxymethyltransferase - Salmonella typhi| Length = 417 Score = 349 bits (895), Expect = 3e-95 Identities = 188/397 (47%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L Sbjct: 68 CEYVDVVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQ 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DES G IDYD++ K A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGIDES-GKIDYDEMAKLAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GL+AAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFP QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGDEELYK-----------KLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEFKV 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E ++GY +VSGGT+NHL L++L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+G+PA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELA 383
>Q5PII3:GLYA_SALPA Serine hydroxymethyltransferase - Salmonella paratyphi-a| Length = 417 Score = 349 bits (895), Expect = 3e-95 Identities = 188/397 (47%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L Sbjct: 68 CEYVDVVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQ 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DES G IDYD++ K A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGIDES-GKIDYDEMAKLAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GL+AAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFP QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGDEELYK-----------KLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEFKV 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E ++GY +VSGGT+NHL L++L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+G+PA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELA 383
>Q57LF7:GLYA_SALCH Serine hydroxymethyltransferase - Salmonella choleraesuis| Length = 417 Score = 349 bits (895), Expect = 3e-95 Identities = 188/397 (47%), Positives = 253/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E EK RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP SGS ANF VYTALL+P D ++ ++L Sbjct: 68 CEYVDVVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQ 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DES G IDYD++ K A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGIDES-GKIDYDEMAKLAKEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GL+AAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFP QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGDEELYK-----------KLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEFKV 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E ++GY +VSGGT+NHL L++L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+G+PA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELA 383
>Q8TK94:GLYA_METAC Serine hydroxymethyltransferase - Methanosarcina acetivorans| Length = 412 Score = 349 bits (895), Expect = 3e-95 Identities = 188/402 (46%), Positives = 252/402 (62%), Gaps = 1/402 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +E++DP++ + I+ E RQ L LI SEN+ S +VM+A GS+MTNKY+EGY G RYYGG Sbjct: 4 IEKIDPDMFEAIQKEADRQEHKLNLIASENYASRAVMEAQGSIMTNKYAEGYSGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 +++D+AE L RA E F VNVQP SGS AN VY ++L+P D IM++DL H Sbjct: 64 CDFVDIAENLAIARAKEIFGAKY----VNVQPHSGSGANMAVYFSVLQPGDTIMSMDLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHLSHG +S + +PY + + T +DYD+L K A +PK+IV GASAY Sbjct: 120 GGHLSHG-----SPVSFSGKLYNIVPYGVSKETEALDYDELMKMAKECKPKMIVCGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ + R+I D+ A LLAD+AHI+GLV +GV PSP YAD VTTTTHK+LRGPRG Sbjct: 175 PRVIDFKKFREIADEVGAYLLADIAHIAGLVVSGVHPSPVPYADFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI + + +N AVFPG+QGGP H I AVA K+A +++R Sbjct: 235 MIISK-------------TEELAMGVNKAVFPGIQGGPLMHVIAAKAVAFKEAMDEKFRQ 281 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Q Q + N+ L KG+DIVSGGTDNHL+LVNL I G E + I ANK Sbjct: 282 DQAQTVKNAKVLCACLKEKGFDIVSGGTDNHLMLVNLNNMNITGKDAEAAMSKAGIIANK 341 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS 1430 NTVP + S + G+R+GTPA T+RG E++ +A++ ++ Sbjct: 342 NTVPFETRSPFITSGVRLGTPACTTRGMKEKEMELIADYIET 383
>Q8EBN8:GLYA_SHEON Serine hydroxymethyltransferase - Shewanella oneidensis| Length = 417 Score = 348 bits (894), Expect = 4e-95 Identities = 187/392 (47%), Positives = 254/392 (64%), Gaps = 1/392 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + DPE+ + I+ E RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDPELFNAIQNETLRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ ETL +RA + F NVQP SGS AN VY ALLKP D ++ ++L H Sbjct: 68 CEYVDVVETLAIERAKQLFGATY----ANVQPHSGSQANSAVYMALLKPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DES G IDYD++E+ AV +PK+++ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGRLYNIIPYGIDES-GKIDYDEMERLAVEHKPKMMIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ RMR+I DK A L DMAH++GL+AAGV P+P +A VVT+TTHK+L GPRG Sbjct: 178 SGIVDWARMREIADKIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTSTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +E+ K K+N+AVFPG QGGP H I G AVA K+A E++ Sbjct: 238 IILSAADDEELYK-----------KLNSAVFPGGQGGPLMHVIAGKAVAFKEALEPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV++N+ E +GY IVSGGT NHL+LV+L + + G + L + +I NK Sbjct: 287 YQQQVVNNAKAMVEVFLERGYKIVSGGTSNHLMLVDLIGRDLTGKEADAALGSANITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEED 1400 N+VP D S V G+R+GTPA+T RGF E + Sbjct: 347 NSVPNDPRSPFVTSGVRIGTPAITRRGFKEAE 378
>Q87WC1:GLYA2_PSESM Serine hydroxymethyltransferase 2 - Pseudomonas syringae pv. tomato| Length = 417 Score = 348 bits (893), Expect = 5e-95 Identities = 195/454 (42%), Positives = 267/454 (58%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D ++ +E E RQ + +ELI SEN+TS +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 8 IAKYDADLFAAMEQEALRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP +GS AN VY ALL+ D I+ + L H Sbjct: 68 CEYVDVVEQLAIDRAKELFGADY----ANVQPHAGSQANSAVYLALLQGGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG +S+ + + Y +D G+IDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----ASVSSSGKLYNAVQYGID-GNGMIDYDEVERLAVEHKPKMIVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ R R I DK A L DMAH++GLVAAGV P+P +ADVVTTTTHK+LRGPRG Sbjct: 178 SQILDFPRFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R D E K+N+AVFPG QGGP H I A+ K+A E++ Sbjct: 238 LILARANA------------DIEKKLNSAVFPGSQGGPLEHVIAAKAICFKEALQPEFKT 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +G+D+VSGGT+NHL L++L K+ I G + L I NK Sbjct: 286 YQQQVVKNAKAMAGVFIERGFDVVSGGTENHLFLLSLIKQDISGKDADAALGRAFITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R GTPA+T+RGF E + ++A Sbjct: 346 NSVPNDPRSPFVTSGLRFGTPAVTTRGFKETECKELA----------------------- 382 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 ++ + +D N +A I +R V+ + P G Sbjct: 383 GWICDILADLNNEAVIDAVREKVKAICAKLPVYG 416
>Q88AD1:GLYA1_PSESM Serine hydroxymethyltransferase 1 - Pseudomonas syringae pv. tomato| Length = 417 Score = 348 bits (892), Expect = 6e-95 Identities = 183/388 (47%), Positives = 246/388 (63%), Gaps = 1/388 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++ D + + E+ RQ +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IQGYDDALLSAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L +RA + F D NVQP SGS AN VY ALL+ D ++ + L H Sbjct: 68 CEHVDKVEQLAIERARQLFGADY----ANVQPHSGSQANAAVYLALLQAGDTVLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K+S + + Y +D +TGLIDYD++E+ AV +PK+++AG SAY Sbjct: 124 GGHLTHG-----AKVSFSGKLYNAVQYGIDTTTGLIDYDEVERIAVECQPKMLIAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R I DK A L DMAH++GLVAAG+ P+P YADVVTTTTHK+LRGPRG Sbjct: 179 SKTLDFPRFRAIADKVGAYLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + + E K N+AVFPG QGGP H I AV K+A ++ Sbjct: 239 LIL------------AKANEELEKKFNSAVFPGGQGGPLMHVIAAKAVCFKEAMEPGFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A+ ++G+D+VSGGTDNHL LV+L ++G+ G + L HI NK Sbjct: 287 YQQQVIDNAQAMAQVFITRGFDVVSGGTDNHLFLVSLIRQGLTGKEADAALGRAHITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGF 1388 N+VP D S V G+R+GTPA+T+RGF Sbjct: 347 NSVPNDPQSPFVTSGLRIGTPAVTTRGF 374
>Q30YL7:GLYA_DESDG Serine hydroxymethyltransferase - Desulfovibrio desulfuricans (strain| G20) Length = 412 Score = 347 bits (891), Expect = 8e-95 Identities = 201/447 (44%), Positives = 266/447 (59%), Gaps = 1/447 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 DPE+ I E RQ LELI SENF S +V A GSV+T+KY+EGYPG RYYGG E++ Sbjct: 8 DPEVGRAIVQEVERQTGKLELIASENFVSPAVRAAQGSVLTHKYAEGYPGKRYYGGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+AE L RA E F NVQP SGS AN VY + L P D I+A+DL HGGHL Sbjct: 68 DVAENLAIDRACEIFGAQY----ANVQPHSGSQANMAVYFSALTPGDTILAMDLSHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F+ + Y + TG IDYD + + A RP +IVAGASAY+R+ Sbjct: 124 THG-----SPVNFSGRFYNVVFYGVSRETGCIDYDSVAELAREHRPAMIVAGASAYSRII 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R R I D+ ++L+ DMAHI+GLVAAG+ PSP A TTTTHK+LRGPRG MI Sbjct: 179 DFARFRAIADEVGSLLMVDMAHIAGLVAAGLHPSPVGTAHFTTTTTHKTLRGPRGGMILS 238 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 + + K+N+ +FPG+QGGP H I AVA +A E+ AYQ+Q Sbjct: 239 DE--------------EAAKKLNSQIFPGIQGGPLMHVIAAKAVAFGEALRPEFGAYQKQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V++N+A+ A +LT G+++VSGGTDNHL+LV+L K I G + L+ I ANKNTVP Sbjct: 285 VVANAAKLAATLTDAGFELVSGGTDNHLMLVDLTNKDITGKDAQHALDLAGITANKNTVP 344 Query: 1320 GDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFVA 1496 + S V GIR+GTPALT+RG E + KVA + + Sbjct: 345 FETRSPFVTSGIRLGTPALTTRGMKEAEMVKVAGW----------------------IID 382 Query: 1497 TLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 L + N + +A++ DVE++A+QFP Sbjct: 383 ALGNIGN-ETRLAEISRDVEKFARQFP 408
>Q88UT5:GLYA_LACPL Serine hydroxymethyltransferase - Lactobacillus plantarum| Length = 412 Score = 347 bits (890), Expect = 1e-94 Identities = 190/398 (47%), Positives = 255/398 (64%), Gaps = 2/398 (0%) Frame = +3 Query: 231 EEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGN 410 +E DPE+ I E+ARQ +ELI SEN S V A GSV+TNKYSEGYPG R+YGGN Sbjct: 4 QEQDPEVWAAISKEQARQQHNIELIASENIVSKGVRAAQGSVLTNKYSEGYPGHRFYGGN 63 Query: 411 EYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHG 590 EYID ETL +RA + F + NVQP SGS AN Y AL++P DR+M + L G Sbjct: 64 EYIDQVETLAIERAKKLFGAEY----ANVQPHSGSQANAAAYMALIQPGDRVMGMSLDAG 119 Query: 591 GHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYA 770 GHL+HG ++ ++ Y LD T ++YD + A F+PKLIVAGASAY+ Sbjct: 120 GHLTHG-----SSVNFSGKLYDFQGYGLDPETAELNYDAILAQAQDFQPKLIVAGASAYS 174 Query: 771 RLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAM 950 RL D+ + R+I D+ A+L+ DMAHI+GLVAAG+ P+P YADVVTTTTHK+LRGPRG M Sbjct: 175 RLIDFKKFREIADQVGALLMVDMAHIAGLVAAGLHPNPVPYADVVTTTTHKTLRGPRGGM 234 Query: 951 IFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAY 1130 I ++ K GK KIN+AVFPG QGGP +H I G A+AL + E++ Y Sbjct: 235 ILAKE------KYGK--------KINSAVFPGNQGGPLDHVIAGKAIALGEDLQPEFKVY 280 Query: 1131 QEQVMSNSARFAESLT-SKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 + ++ N+ A+ S ++SGGTDNHL+ +++ K G++G +V+ +L+ V+I NK Sbjct: 281 AQHIIDNAKAMAKVFNDSDLVRVISGGTDNHLMTIDVTKSGLNGRQVQDLLDTVYITVNK 340 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 +P + + A GIR+GTPA+T+RGF E D KVAE Sbjct: 341 EAIPNETLGAFKTSGIRLGTPAITTRGFDEADATKVAE 378
>Q8Y1G1:GLYA1_RALSO Serine hydroxymethyltransferase 1 - Ralstonia solanacearum| (Pseudomonas solanacearum) Length = 415 Score = 347 bits (890), Expect = 1e-94 Identities = 198/451 (43%), Positives = 267/451 (59%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++++DPE+ I+ E RQ +ELI SEN+TS +VM A GS +TNKY+EGYPG RYYGG Sbjct: 9 IDQIDPEVFAAIQQENQRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L R + F + NVQP SGS AN V+ A+LKP D IM + L Sbjct: 69 CEYVDVVEQLAIDRVKQLFGAE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAE 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y L+ IDYD LE A +PKLI+AGASA+ Sbjct: 125 GGHLTHGMA-----LNMSGKWFNVVSYGLNAQED-IDYDALEALAQEKKPKLIIAGASAF 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 A D+ R+ K+ A + DMAH +GL+AAGV P+P +AD VTTTTHKSLRGPRG Sbjct: 179 ALRIDFERIAKVAKAVGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +K + E IN+A+FPG+QGGP H I G AVA K+A + ++A Sbjct: 239 VIL--------------MKAEHEKAINSAIFPGIQGGPLMHVIAGKAVAFKEAQSPTFKA 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQEQV+ N+ AE+L ++G IVSG T++H++LV+L+ K I G EKVL + HI NK Sbjct: 285 YQEQVVKNARAMAETLMARGLRIVSGRTESHVMLVDLRAKSITGKEAEKVLGDAHITVNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D V GIR+G+PA+T+RGF E + KVA Sbjct: 345 NAIPNDPEKPFVTSGIRLGSPAMTTRGFKEGEAVKVAH---------------------- 382 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 +A + + + +A IA +R V E KQFP Sbjct: 383 -LIADVLDNPHDEANIAAVRAKVAELTKQFP 412
>Q8UG75:GLYA1_AGRT5 Serine hydroxymethyltransferase 1 - Agrobacterium tumefaciens (strain| C58 / ATCC 33970) Length = 429 Score = 347 bits (890), Expect = 1e-94 Identities = 190/399 (47%), Positives = 248/399 (62%), Gaps = 1/399 (0%) Frame = +3 Query: 225 PLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYG 404 PL EVDP+I IE E RQ +ELI SEN S +V++A GS+MTNKY+EGYPG RYYG Sbjct: 11 PLAEVDPDIFGAIEKELGRQRHEIELIASENIVSRAVLEAQGSIMTNKYAEGYPGKRYYG 70 Query: 405 GNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLP 584 G +++D+AE L +RA + F ++ NVQP SGS N V+ ALL+P D M LDL Sbjct: 71 GCQFVDIAEELAIERAKKLFGVN----FANVQPNSGSQMNQAVFLALLQPGDTFMGLDLN 126 Query: 585 HGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASA 764 GGHL+HG ++ +F + Y + E L+D D++E+ A RPKLI+AG +A Sbjct: 127 SGGHLTHG-----SPVNMSGKWFNVVSYGVREGDNLLDMDEVERKAKETRPKLILAGGTA 181 Query: 765 YARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRG 944 Y+R++D+ R R+I D+ A L+ DMAHI+GLVA G PSPF + V TTTTHKSLRGPRG Sbjct: 182 YSRVWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPFPHCHVATTTTHKSLRGPRG 241 Query: 945 AMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 MI D K N+AVFPGLQGGP H I AVA +A E++ Sbjct: 242 GMILTN-------------DEDLAKKFNSAVFPGLQGGPLMHVIAAKAVAFGEALQPEFK 288 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAAN 1304 Y QV+ N+ AE+L G D+VSGGTDNHL+LV+L+KK G R E L +I N Sbjct: 289 DYAAQVVKNAKALAETLIEGGLDVVSGGTDNHLMLVDLRKKNATGKRAEAALGRAYITCN 348 Query: 1305 KNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 KN +P D V G+R+GTPA T+RGF E +F ++ + Sbjct: 349 KNGIPFDPEKPFVTSGVRLGTPAGTTRGFKEAEFREIGK 387
>Q2LQM6:GLYA_SYNAS Serine hydroxymethyltransferase - Syntrophus aciditrophicus (strain| SB) Length = 417 Score = 347 bits (889), Expect = 1e-94 Identities = 184/397 (46%), Positives = 250/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L + DPEIA+ I LE RQ LELI SENF S +V++A G +MTNKY+EGYPG RYYGG Sbjct: 4 LMKTDPEIAEAIRLETRRQAGKLELIASENFVSEAVLEAQGCIMTNKYAEGYPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+AE L +R F D VNVQP SG+ AN VY + L D I+ ++L H Sbjct: 64 CEYVDIAENLAIERCKALFGADY----VNVQPHSGTQANMAVYFSALSVGDTILGMNLAH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHLSHG + F+ +PY +D T IDY+Q+E A+ +P++IV GASAY Sbjct: 120 GGHLSHGSPANFS-----GKFYNVVPYGVDRETETIDYNQVEDLALQHKPRMIVVGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + R I DK A+++AD+AHI+GLVA G+ PSP + VT+TTHK+LRGPRG Sbjct: 175 PRTIDFEKFRAIADKVGALVMADIAHIAGLVATGLHPSPVPVCEYVTSTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 ++ + ++ +++ VFPG+QGGP H I AVA K+A T E++ Sbjct: 235 LVM--------------CQASYQKTLSSRVFPGVQGGPLMHIIAAKAVAFKEALTDEFKD 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ Q++ N+ A+ L +GY +VSGGTDNHL+L++L KG+ G ++ L++ I NK Sbjct: 281 YQSQIVKNAQALAKELIGRGYRLVSGGTDNHLLLMDLTDKGLTGKEAQESLDSAGITVNK 340 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N +P D MV GIR+GTPALTSRG EE+ +A Sbjct: 341 NGIPFDTRGPMVTSGIRIGTPALTSRGMKEEEMRTIA 377
>O08370:GLYA_RICPR Serine hydroxymethyltransferase - Rickettsia prowazekii| Length = 420 Score = 347 bits (889), Expect = 1e-94 Identities = 199/409 (48%), Positives = 256/409 (62%), Gaps = 5/409 (1%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 LN L E+D EI +II+ EK RQ +ELI SENF S +V++A GS++TNKY+EGYP R Sbjct: 4 LNNNLYEMDKEIYEIIKNEKIRQNNVIELIASENFVSSAVLEAQGSILTNKYAEGYPSKR 63 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 +Y G + +D AE L +R + FN NVQP SGS AN VY ALL+P D I+ + Sbjct: 64 FYNGCDEVDKAEVLAIERIKKLFNCKY----ANVQPHSGSQANQTVYLALLQPCDTILGM 119 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 L GGHL+HG + +F T+ Y +D+ T LIDYD++E+ AVL PKL++AG Sbjct: 120 SLDSGGHLTHGAAPNIS-----GKWFNTVSYHVDQETYLIDYDEVERLAVLHNPKLLIAG 174 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 SAY R D+ + RKI DK A L+AD+AHI+GLVA G SP YA VVT+TTHK+LRG Sbjct: 175 FSAYPRKIDFAKFRKIADKVGAYLMADIAHIAGLVATGEHQSPIPYAHVVTSTTHKTLRG 234 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG +I +EI K KIN+A+FPGLQGGP H I AVA + Sbjct: 235 PRGGLIL--SDDEEIGK-----------KINSALFPGLQGGPLMHIIAAKAVAFLENLQP 281 Query: 1116 EYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHI 1295 EY+ Y +QV+SN+ A SL +GYDI++GGTDNH+VLV+L+K GI G L+ I Sbjct: 282 EYKNYIKQVISNAKALAISLQERGYDILTGGTDNHIVLVDLRKDGITGKCAANSLDRAGI 341 Query: 1296 AANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFA----KVAEFFD 1427 NKN +P D S + GIR GTPA T++GF E+DF VAE D Sbjct: 342 TCNKNAIPFDTTSPFITSGIRFGTPACTTKGFKEKDFVLIGHMVAEILD 390
>Q46A52:GLYA_METBF Serine hydroxymethyltransferase - Methanosarcina barkeri (strain| Fusaro / DSM 804) Length = 412 Score = 347 bits (889), Expect = 1e-94 Identities = 188/402 (46%), Positives = 253/402 (62%), Gaps = 1/402 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +E+ DPE+ + I+ E RQ L LI SEN+ S +VM+A GS++TNKY+EGY G RYYGG Sbjct: 4 IEKTDPELFEAIKKEAERQEYKLNLIASENYASKAVMEAQGSILTNKYAEGYSGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 +++D+AE L RA + FN VNVQP SGS AN VY ++LKP D IM++DL H Sbjct: 64 CDFVDIAEDLAIARAKKIFNAGY----VNVQPHSGSGANMAVYFSVLKPGDTIMSMDLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHLSHG +S F +PY + + T ++DY +L K A +P++IV GASAY Sbjct: 120 GGHLSHG-----SPVSFSGKLFNIVPYGVSKKTEMLDYSELMKKAKENKPQMIVCGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + R+I D+ A LLAD+AHI+GLV AGV PSP YAD VT+TTHK+LRGPRG Sbjct: 175 PREIDFKQFREIADEVGAYLLADIAHIAGLVVAGVHPSPVPYADFVTSTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + + +IN AVFPGLQGGP H I G AVA K+A +++++ Sbjct: 235 IIISK-------------TEELATRINKAVFPGLQGGPLMHIIAGKAVAFKEAMSEKFKQ 281 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Q Q + N+ + L KG+D+VSG TDNHL+LVNL I G E L I ANK Sbjct: 282 DQVQTVKNAKTLCKCLKEKGFDMVSGDTDNHLMLVNLNNMNITGKDAEAALSKAGIIANK 341 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS 1430 NTVP + S + G+R+GTPA T+RG E + +A++ ++ Sbjct: 342 NTVPFETRSPFITSGVRLGTPACTTRGMKETEMELIADYIET 383
>P77962:GLYA_SYNY3 Serine hydroxymethyltransferase - Synechocystis sp. (strain PCC 6803)| Length = 427 Score = 346 bits (888), Expect = 2e-94 Identities = 185/393 (47%), Positives = 254/393 (64%), Gaps = 1/393 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 DP +A II+ E RQ +ELI SENFTS +VM A GSV+TNKY+EG PG RYYGG E++ Sbjct: 13 DPALAAIIDRELQRQRTHIELIASENFTSAAVMAAQGSVLTNKYAEGLPGKRYYGGCEFV 72 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D AETL R E F NVQP SG+ ANF V+ LL+P D IM +DL HGGHL Sbjct: 73 DQAETLAISRVKELFGAAH----ANVQPHSGAQANFAVFLTLLQPGDTIMGMDLSHGGHL 128 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ +FE Y +++ TG +DYD++ + A+ +PKL++ G SAY R Sbjct: 129 THG-----SPVNVSGKWFEVAHYGVEKETGRLDYDKIRQQALEVKPKLLICGYSAYPRQI 183 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 ++++ R I D+ A L+AD+AHI+GLVA+G PSP Y DVVTTTTHK+LRGPRG +I Sbjct: 184 EFDKFRAIADEVGAYLMADIAHIAGLVASGHHPSPLPYCDVVTTTTHKTLRGPRGGLIMT 243 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 +E+ K K + +VFPG QGGP H IT AVA +A E++ Y Q Sbjct: 244 NN--EELGK-----------KFDKSVFPGTQGGPLEHVITAKAVAFGEALKPEFKVYSGQ 290 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V++N+ A+ L +G+D+VSGGTDNHL+LV+L+ + G +++L ++I ANKNTVP Sbjct: 291 VIANAQAMADQLQKRGFDLVSGGTDNHLMLVDLRSIAMTGKVGDQLLGEINITANKNTVP 350 Query: 1320 GD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 D S V G+R+G+PA+T+RG E++F +A Sbjct: 351 FDPESPFVTSGLRLGSPAMTTRGMQEDEFRTIA 383
>Q2NS25:GLYA_SODGM Serine hydroxymethyltransferase - Sodalis glossinidius (strain| morsitans) Length = 417 Score = 346 bits (888), Expect = 2e-94 Identities = 188/397 (47%), Positives = 249/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ +E E RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELWHAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA F D NVQP SGS ANF VYT LL+P D ++ ++L H Sbjct: 68 CEYVDVVEQLAIDRAKALFGADY----ANVQPHSGSQANFAVYTTLLQPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DES G IDYDQL + A +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGIDES-GHIDYDQLAELAKTHQPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ RMR+I D A L DMAH++GL+AAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SGVVDWARMRQIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +E+ K K+N+AVFPG QGGP H I AVALK+A ++ Sbjct: 238 LILAKGGSEELYK-----------KLNSAVFPGAQGGPLMHVIAAKAVALKEAMEPAFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E S+G+++VSG TDNHL L++L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLSRGFNVVSGATDNHLFLLDLVDKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V G+R+GTPA+T RGF E D +A Sbjct: 347 NSVPNDPKSPFVTSGMRIGTPAVTRRGFTEADVRDLA 383
>Q3A4L9:GLYA_PELCD Serine hydroxymethyltransferase - Pelobacter carbinolicus (strain DSM| 2380 / Gra Bd 1) Length = 416 Score = 346 bits (888), Expect = 2e-94 Identities = 196/455 (43%), Positives = 262/455 (57%), Gaps = 1/455 (0%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 ++ L + DPEIA+ I LE RQ LE I SENF S VM+A GS+MTNKY+EGYP R Sbjct: 1 MSQTLIQQDPEIAEAIRLETERQEYNLEFIASENFVSEQVMEAQGSIMTNKYAEGYPAKR 60 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 YYGG E +D+AE L +RA E F + NVQ SGS AN VY A KP D ++ + Sbjct: 61 YYGGCEMVDIAERLAIERAKELFGAEH----ANVQAHSGSQANMAVYFAACKPGDTVLGM 116 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 +L HGGHL+HG ++ F + Y + + TG IDY+++E+ A+ +P L+V G Sbjct: 117 NLAHGGHLTHG-----SPVNFSGKLFNIVSYGVQKETGYIDYEEVERLALEHKPTLLVVG 171 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 ASAY R D+ RKI DK A ++ DMAHI+GLVAAGV PSP YA+ VTTTTHK+LRG Sbjct: 172 ASAYPRTIDFPAFRKIADKVGAKIMVDMAHIAGLVAAGVHPSPVPYAEFVTTTTHKTLRG 231 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG MI R+ +F I++ +FPG+QGGP H I AV+ K+A Sbjct: 232 PRGGMILCRE--------------EFAKTIDSNIFPGIQGGPLMHVIAAKAVSFKEALAP 277 Query: 1116 EYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHI 1295 E++ Y QV+ N+ A++L +G ++VSGGTDNHL+LV+ G EK LE I Sbjct: 278 EFKEYSTQVVKNAKVLADALVKRGLNLVSGGTDNHLILVDFTGTETTGKMAEKALEKAGI 337 Query: 1296 AANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXG 1472 NKN+VP + S V GIR+GTPA T+RG E + +VA Sbjct: 338 TVNKNSVPFETRSPFVTSGIRLGTPATTTRGLKEAEMERVA------------------- 378 Query: 1473 TKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 D+V + E+A ++ +V E K+FP Sbjct: 379 ----DWVVRALDNMENDTELAAIKGEVREMCKRFP 409
>Q474L3:GLYA1_RALEJ Serine hydroxymethyltransferase 1 - Ralstonia eutropha (strain| JMP134) (Alcaligenes eutrophus) Length = 415 Score = 346 bits (888), Expect = 2e-94 Identities = 196/454 (43%), Positives = 267/454 (58%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++++DPE+ I+ E RQ +ELI SEN+TS +VM A GS +TNKY+EGYPG RYYGG Sbjct: 9 IDQIDPEVFAAIQKENQRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L R + F + NVQP SGS AN VY A+LKP D IM + L Sbjct: 69 CEYVDIVEQLAIDRVKQLFGAE----AANVQPNSGSQANQGVYFAVLKPGDTIMGMSLAE 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y L+ IDYD LEK A +PKLI+AGASA+ Sbjct: 125 GGHLTHGMA-----LNMSGKWFNVVSYGLNAQED-IDYDALEKLAQEKKPKLIIAGASAF 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 A D+ R+ K+ A + DMAH +GL+AAGV P+P +AD VTTTTHKSLRGPRG Sbjct: 179 ALRIDFERIGKVAKSIGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +K + E IN+++FPG+QGGP H I G AVA K+A T E++A Sbjct: 239 VIL--------------MKAEHEKAINSSIFPGIQGGPLMHVIAGKAVAFKEALTPEFKA 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQEQV+ N+A AE+L ++G IVSG T++H++LV+L+ K I G E++L H+ NK Sbjct: 285 YQEQVVKNAAVLAETLIARGLRIVSGRTESHVMLVDLRAKNITGKEAERILGEAHLTVNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D V GIR+G+PA+T+RGF EE+ V Sbjct: 345 NAIPNDPEKPFVTSGIRVGSPAMTTRGFKEEEARIVG----------------------- 381 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 + +A + + + IA +R V K+FP G Sbjct: 382 NLIADVLDNPHDAGNIASVREQVSALTKRFPVYG 415
>Q5GW07:GLYA_XANOR Serine hydroxymethyltransferase - Xanthomonas oryzae pv. oryzae| Length = 417 Score = 345 bits (886), Expect = 3e-94 Identities = 197/454 (43%), Positives = 265/454 (58%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE DPE+A I E RQ +ELI SEN+ S VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 LETYDPELAKAIAAEAGRQEDHVELIASENYCSQLVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 ++D+AE L R + F+ D NVQP SGS AN VY ALL+P D I+ + L H Sbjct: 68 CAFVDIAEQLAIDRIKQVFDADY----ANVQPHSGSQANQAVYLALLQPGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K + F + Y ++E GLIDYD++++ A PK++VAG SAY Sbjct: 124 GGHLTHG-----AKANVSGKLFNAVQYGVNEQ-GLIDYDEVQRLATEHTPKMVVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R I D A L DMAHI+GLVAAGV PSP E+A VVT+TTHK+LRGPRG Sbjct: 178 SQKIDWARFRAIADSVGAYLFVDMAHIAGLVAAGVYPSPMEHAHVVTSTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + +E+ K K+ + VFPG+QGGP H I AVA K+A ++ Sbjct: 238 IIVAKGASEELQK-----------KLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +L ++GY IVSGGT+NHL+LV++ + + G E L HI NK Sbjct: 287 YQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N VP D S V G+R+GTPA+T+RG+ E D L Sbjct: 347 NAVPNDPRSPFVTSGLRLGTPAITTRGYKEPD-----------------------SIDLA 383 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 +++A + +A +AK+R V K++P G Sbjct: 384 NWIADVLDAPTDEAVLAKVRDAVTAQCKRYPVYG 417
>Q2NZ83:GLYA_XANOM Serine hydroxymethyltransferase - Xanthomonas oryzae pv. oryzae| (strain MAFF 311018) Length = 417 Score = 345 bits (886), Expect = 3e-94 Identities = 197/454 (43%), Positives = 265/454 (58%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE DPE+A I E RQ +ELI SEN+ S VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 LETYDPELAKAIAAEAGRQEDHVELIASENYCSQLVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 ++D+AE L R + F+ D NVQP SGS AN VY ALL+P D I+ + L H Sbjct: 68 CAFVDIAEQLAIDRIKQVFDADY----ANVQPHSGSQANQAVYLALLQPGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K + F + Y ++E GLIDYD++++ A PK++VAG SAY Sbjct: 124 GGHLTHG-----AKANVSGKLFNAVQYGVNEQ-GLIDYDEVQRLATEHTPKMVVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 ++ D+ R R I D A L DMAHI+GLVAAGV PSP E+A VVT+TTHK+LRGPRG Sbjct: 178 SQKIDWARFRAIADSVGAYLFVDMAHIAGLVAAGVYPSPMEHAHVVTSTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + +E+ K K+ + VFPG+QGGP H I AVA K+A ++ Sbjct: 238 IIVAKGASEELQK-----------KLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +L ++GY IVSGGT+NHL+LV++ + + G E L HI NK Sbjct: 287 YQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N VP D S V G+R+GTPA+T+RG+ E D L Sbjct: 347 NAVPNDPRSPFVTSGLRLGTPAITTRGYKEPD-----------------------SIDLA 383 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 +++A + +A +AK+R V K++P G Sbjct: 384 NWIADVLDAPTDEAVLAKVRDAVTAQCKRYPVYG 417
>Q4ZNH2:GLYA1_PSEU2 Serine hydroxymethyltransferase 1 - Pseudomonas syringae pv. syringae| (strain B728a) Length = 417 Score = 345 bits (886), Expect = 3e-94 Identities = 194/454 (42%), Positives = 267/454 (58%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D ++ +E E RQ + +ELI SEN+TS +VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 IAKYDADLFAAMEQEALRQEEHIELIASENYTSPAVMEAQGSALTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP +GS AN VY ALL+ D I+ + L H Sbjct: 68 CEYVDIIEQLAIDRAKELFGADY----ANVQPHAGSQANSAVYLALLQGGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG +S+ + + Y +D + G+IDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----ASVSSSGKLYNAVQYGID-ANGMIDYDEVERLAVEHKPKMIVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ R R I DK A L DMAH++GLVAAGV P+P +ADVVTTTTHK+LRGPRG Sbjct: 178 SQILDFPRFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R + E K+N+AVFPG QGGP H I AV K+A E++ Sbjct: 238 LILARANA------------EIEKKLNSAVFPGSQGGPLEHVIAAKAVCFKEALQPEFKT 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +G+D+VSGGT+NHL L++L K+ I G + L I NK Sbjct: 286 YQQQVVKNAKAMAGVFIERGFDVVSGGTENHLFLLSLIKQDISGKDADAALGRAFITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R GTPA+T+RGF E + ++A Sbjct: 346 NSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELA----------------------- 382 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 ++ + +D N +A I +R V+ + P G Sbjct: 383 GWICDILADLNNEAVIDAVREKVKAICAKLPVYG 416
>Q48DU7:GLYA1_PSE14 Serine hydroxymethyltransferase 1 - Pseudomonas syringae pv.| phaseolicola (strain 1448A / Race 6) Length = 417 Score = 345 bits (886), Expect = 3e-94 Identities = 194/454 (42%), Positives = 267/454 (58%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D ++ +E E RQ + +ELI SEN+TS +VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 IAKYDADLFAAMEQEALRQEEHIELIASENYTSPAVMEAQGSALTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA E F D NVQP +GS AN VY ALL+ D I+ + L H Sbjct: 68 CEYVDVIEQLAIDRAKELFGADY----ANVQPHAGSQANSAVYLALLQGGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG +S+ + + Y +D + G+IDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----ASVSSSGKLYNAVQYGID-ANGMIDYDEVERLAVEHKPKMIVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ R R I DK A L DMAH++GLVAAGV P+P +ADVVTTTTHK+LRGPRG Sbjct: 178 SQILDFPRFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R + E K+N+AVFPG QGGP H I AV K+A E++ Sbjct: 238 LILARANA------------EIEKKLNSAVFPGSQGGPLEHVIAAKAVCFKEALQPEFKT 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A +G+D+VSGGT+NHL L++L K+ I G + L I NK Sbjct: 286 YQQQVVKNAKAMAGVFIERGFDVVSGGTENHLFLLSLIKQDISGKDADAALGRAFITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N+VP D S V G+R GTPA+T+RGF E + ++A Sbjct: 346 NSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELA----------------------- 382 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 ++ + +D N +A I +R V+ + P G Sbjct: 383 GWICDILADLNNEAVIDAVREKVKAICAKLPVYG 416
>Q5SI56:GLYA_THET8 Serine hydroxymethyltransferase - Thermus thermophilus (strain HB8 /| ATCC 27634 / DSM 579) Length = 407 Score = 345 bits (885), Expect = 4e-94 Identities = 190/397 (47%), Positives = 251/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D + ++I LE+ RQ +GLELI SENF S V +AVGSV+TNKY+EGYPGARYYGG E I Sbjct: 8 DEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCEVI 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D E+L +RA F W NVQP SGS AN VY AL++P D +M +DL GGHL Sbjct: 68 DRVESLAIERAKALFGA---AWA-NVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG +++ ++ + Y + T LID +++ + A+ RPK+IVAGASAY R + Sbjct: 124 THG-----SRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPRFW 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R+I D+ A L+ DMAH +GLVAAG+ P+P YA VVT+TTHK+LRGPRG +I Sbjct: 179 DFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 E+ K +I+ +FPG+QGGP H I G AVA +A E++ Y Sbjct: 238 -SNDPELGK-----------RIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEYSRL 285 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V+ N+ R AE L +GY IV+GGTDNHL LV+L+ KG+ G E+ L+ V I NKN +P Sbjct: 286 VVENAKRLAEELARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKNAIP 345 Query: 1320 GDVS-AMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 D V GIR+GTPA+T+RGF E+ VAE D Sbjct: 346 FDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELID 382
>Q72IH2:GLYA_THET2 Serine hydroxymethyltransferase - Thermus thermophilus (strain HB27 /| ATCC BAA-163 / DSM 7039) Length = 407 Score = 345 bits (885), Expect = 4e-94 Identities = 190/397 (47%), Positives = 252/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D + ++I LE+ RQ +GLELI SENF S V +AVGSV+TNKY+EGYPGARYYGG E I Sbjct: 8 DEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCEAI 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D E+L +RA F W NVQP SGS AN VY AL++P D +M +DL GGHL Sbjct: 68 DRVESLAIERAKALFGA---AWA-NVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG +++ ++ + Y + T LID +++ + A+ RPK+IVAGASAY R + Sbjct: 124 THG-----SRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPRFW 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R+I D+ A L+ DMAH +GLVAAG+ P+P YA VVT+TTHK+LRGPRG +I Sbjct: 179 DFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 E+ K +I+ +FPG+QGGP H I G AVA +A E++ Y Sbjct: 238 -SNDPELGK-----------RIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEYSRL 285 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V+ N+ R AE+L +GY IV+GGTDNHL LV+L+ KG+ G E+ L+ V I NKN +P Sbjct: 286 VVENAKRLAEALARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKNAIP 345 Query: 1320 GDVS-AMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 D V GIR+GTPA+T+RGF E+ VAE D Sbjct: 346 FDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELID 382
>P66804:GLYA_STAAW Serine hydroxymethyltransferase - Staphylococcus aureus (strain MW2)| Length = 412 Score = 345 bits (885), Expect = 4e-94 Identities = 187/395 (47%), Positives = 255/395 (64%), Gaps = 2/395 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D IA+ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG E++ Sbjct: 8 DKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E++ RA F + VNVQP SGS AN VY L+ D ++ ++L HGGHL Sbjct: 68 DVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F+ + Y +D+ T I+YD++ K A+ +PKLIVAGASAY+R Sbjct: 124 THG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P EYAD VTTTTHK+LRGPRG MI Sbjct: 179 DFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 K +++ I+ +FPG+QGGP H I AVA +A ++ YQ+Q Sbjct: 238 -------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKNTV 1316 V+ N+ AE+L ++G+ IVSGGTDNHLV V++K G+ G E+ L++V I NKNT+ Sbjct: 285 VVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTI 344 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 P D V GIR+GTPA T+RGF E+ F +VA+ Sbjct: 345 PFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAK 379
>Q6G7J7:GLYA_STAAS Serine hydroxymethyltransferase - Staphylococcus aureus (strain| MSSA476) Length = 412 Score = 345 bits (885), Expect = 4e-94 Identities = 187/395 (47%), Positives = 255/395 (64%), Gaps = 2/395 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D IA+ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG E++ Sbjct: 8 DKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E++ RA F + VNVQP SGS AN VY L+ D ++ ++L HGGHL Sbjct: 68 DVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F+ + Y +D+ T I+YD++ K A+ +PKLIVAGASAY+R Sbjct: 124 THG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P EYAD VTTTTHK+LRGPRG MI Sbjct: 179 DFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 K +++ I+ +FPG+QGGP H I AVA +A ++ YQ+Q Sbjct: 238 -------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKNTV 1316 V+ N+ AE+L ++G+ IVSGGTDNHLV V++K G+ G E+ L++V I NKNT+ Sbjct: 285 VVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTI 344 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 P D V GIR+GTPA T+RGF E+ F +VA+ Sbjct: 345 PFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAK 379
>Q6GEW2:GLYA_STAAR Serine hydroxymethyltransferase - Staphylococcus aureus (strain| MRSA252) Length = 412 Score = 345 bits (885), Expect = 4e-94 Identities = 187/395 (47%), Positives = 255/395 (64%), Gaps = 2/395 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D IA+ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG E++ Sbjct: 8 DKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E++ RA F + VNVQP SGS AN VY L+ D ++ ++L HGGHL Sbjct: 68 DVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F+ + Y +D+ T I+YD++ K A+ +PKLIVAGASAY+R Sbjct: 124 THG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P EYAD VTTTTHK+LRGPRG MI Sbjct: 179 DFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 K +++ I+ +FPG+QGGP H I AVA +A ++ YQ+Q Sbjct: 238 -------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKNTV 1316 V+ N+ AE+L ++G+ IVSGGTDNHLV V++K G+ G E+ L++V I NKNT+ Sbjct: 285 VVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTI 344 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 P D V GIR+GTPA T+RGF E+ F +VA+ Sbjct: 345 PFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAK 379
>P99091:GLYA_STAAN Serine hydroxymethyltransferase - Staphylococcus aureus (strain N315)| Length = 412 Score = 345 bits (885), Expect = 4e-94 Identities = 187/395 (47%), Positives = 255/395 (64%), Gaps = 2/395 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D IA+ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG E++ Sbjct: 8 DKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E++ RA F + VNVQP SGS AN VY L+ D ++ ++L HGGHL Sbjct: 68 DVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F+ + Y +D+ T I+YD++ K A+ +PKLIVAGASAY+R Sbjct: 124 THG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P EYAD VTTTTHK+LRGPRG MI Sbjct: 179 DFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 K +++ I+ +FPG+QGGP H I AVA +A ++ YQ+Q Sbjct: 238 -------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKNTV 1316 V+ N+ AE+L ++G+ IVSGGTDNHLV V++K G+ G E+ L++V I NKNT+ Sbjct: 285 VVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTI 344 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 P D V GIR+GTPA T+RGF E+ F +VA+ Sbjct: 345 PFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAK 379
>P66803:GLYA_STAAM Serine hydroxymethyltransferase - Staphylococcus aureus (strain Mu50| / ATCC 700699) Length = 412 Score = 345 bits (885), Expect = 4e-94 Identities = 187/395 (47%), Positives = 255/395 (64%), Gaps = 2/395 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D IA+ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG E++ Sbjct: 8 DKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E++ RA F + VNVQP SGS AN VY L+ D ++ ++L HGGHL Sbjct: 68 DVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F+ + Y +D+ T I+YD++ K A+ +PKLIVAGASAY+R Sbjct: 124 THG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P EYAD VTTTTHK+LRGPRG MI Sbjct: 179 DFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 K +++ I+ +FPG+QGGP H I AVA +A ++ YQ+Q Sbjct: 238 -------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKNTV 1316 V+ N+ AE+L ++G+ IVSGGTDNHLV V++K G+ G E+ L++V I NKNT+ Sbjct: 285 VVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTI 344 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 P D V GIR+GTPA T+RGF E+ F +VA+ Sbjct: 345 PFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAK 379
>Q5HE87:GLYA_STAAC Serine hydroxymethyltransferase - Staphylococcus aureus (strain COL)| Length = 412 Score = 345 bits (885), Expect = 4e-94 Identities = 187/395 (47%), Positives = 255/395 (64%), Gaps = 2/395 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D IA+ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG E++ Sbjct: 8 DKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E++ RA F + VNVQP SGS AN VY L+ D ++ ++L HGGHL Sbjct: 68 DVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F+ + Y +D+ T I+YD++ K A+ +PKLIVAGASAY+R Sbjct: 124 THG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P EYAD VTTTTHK+LRGPRG MI Sbjct: 179 DFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 K +++ I+ +FPG+QGGP H I AVA +A ++ YQ+Q Sbjct: 238 -------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKNTV 1316 V+ N+ AE+L ++G+ IVSGGTDNHLV V++K G+ G E+ L++V I NKNT+ Sbjct: 285 VVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTI 344 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 P D V GIR+GTPA T+RGF E+ F +VA+ Sbjct: 345 PFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAK 379
>Q2YUJ1:GLYA_STAAB Serine hydroxymethyltransferase - Staphylococcus aureus (strain| bovine RF122) Length = 412 Score = 345 bits (884), Expect = 5e-94 Identities = 187/395 (47%), Positives = 255/395 (64%), Gaps = 2/395 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D IA+ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG E++ Sbjct: 8 DKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E++ RA F + VNVQP SGS AN VY L+ D ++ ++L HGGHL Sbjct: 68 DVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLRHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F+ + Y +D+ T I+YD++ K A+ +PKLIVAGASAY+R Sbjct: 124 THG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P EYAD VTTTTHK+LRGPRG MI Sbjct: 179 DFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 K +++ I+ +FPG+QGGP H I AVA +A ++ YQ+Q Sbjct: 238 -------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKNTV 1316 V+ N+ AE+L ++G+ IVSGGTDNHLV V++K G+ G E+ L++V I NKNT+ Sbjct: 285 VVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTI 344 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 P D V GIR+GTPA T+RGF E+ F +VA+ Sbjct: 345 PFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAK 379
>Q2NIT8:GLYA_AYWBP Serine hydroxymethyltransferase - Aster yellows witches'-broom| phytoplasma (strain AYWB) Length = 429 Score = 345 bits (884), Expect = 5e-94 Identities = 191/423 (45%), Positives = 267/423 (63%), Gaps = 4/423 (0%) Frame = +3 Query: 171 LPATEERSAVTWPKQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVG 350 +P +R + L++ D EI D+IE EKARQ + + LI SENF S +V+ A G Sbjct: 1 MPKNTKRKRLCPKMNQKLGLKDQDQEIFDLIEQEKARQKENILLIASENFVSQAVLDAQG 60 Query: 351 SVMTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFH 530 S++TNKY+EGYP ARYY G + +D E + +RA + F NVQP SGS AN Sbjct: 61 SILTNKYAEGYPQARYYNGCKNVDQIEKIAIQRATKLFGAKY----ANVQPHSGSQANMG 116 Query: 531 VYTALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQL 710 V+ ALLKP D+I+ L L GGHL+HG+ K+S F+E Y ++ T ++DYD++ Sbjct: 117 VFQALLKPGDKILGLSLMDGGHLTHGH-----KLSFSGGFYEAHFYNVNPQTEMLDYDEI 171 Query: 711 EKSAVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFE 890 K A+ +PKLI+AG SAY++ ++ + R+I D+ A L+AD+AHI+GLVA G+ P PFE Sbjct: 172 RKVALAVKPKLIIAGYSAYSKTINFKKFRQIADEVNAYLIADIAHIAGLVACGLHPCPFE 231 Query: 891 -YADVVTTTTHKSLRGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHN 1067 ADVVT+T HK+LRGPRG +I K +E+ K KIN +FPG+QGGP Sbjct: 232 ANADVVTSTMHKTLRGPRGGLILTNK--EELFK-----------KINRGIFPGIQGGPCI 278 Query: 1068 HTITGLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK 1247 HTI AVA ++A ++ YQ+QV+ N+ FA++ KGY IVSG TDNHL L+++K K Sbjct: 279 HTIAAKAVAFQEAMMPSFKEYQKQVIKNANTFAKAFQQKGYRIVSGSTDNHLFLIDVKHK 338 Query: 1248 GID--GSRVEKVLENVHIAANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 + G+++ +LE ++I NKNT+P D V GIR+GTPA+T+ GF E DF VA+ Sbjct: 339 NTEFTGAKIANMLEKINIVVNKNTIPFDQEKPFVTSGIRIGTPAMTTVGFRENDFVAVAD 398 Query: 1419 FFD 1427 D Sbjct: 399 LMD 401
>Q8YMW8:GLYA_ANASP Serine hydroxymethyltransferase - Anabaena sp. (strain PCC 7120)| Length = 427 Score = 345 bits (884), Expect = 5e-94 Identities = 186/396 (46%), Positives = 250/396 (63%), Gaps = 1/396 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L DP IA +I E RQ LELI SENFTS +V+ A GSV+TNKY+EG PG RYYGG Sbjct: 9 LTNSDPAIAGLINQELQRQRDHLELIASENFTSAAVLAAQGSVLTNKYAEGLPGKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E+ID E + RA + F D NVQP SG+ ANF V+ LLKP D+IM +DL H Sbjct: 69 CEFIDKIEQIAIDRAKQLFGADH----ANVQPHSGAQANFAVFLTLLKPGDKIMGMDLSH 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F+ Y + + T +DYDQ+ + A+ RPKL++ G SAY Sbjct: 125 GGHLTHG-----SPVNVSGKWFQVCHYGVSQQTEQLDYDQIRELALRERPKLLICGYSAY 179 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ + R I D+ A LLAD+AHI+GLVA G+ P+P Y DVVTTTTHK+LRGPRG Sbjct: 180 PRIIDFEKFRSIADEVGAYLLADIAHIAGLVATGLHPNPLPYCDVVTTTTHKTLRGPRGG 239 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R E+ K K++ +VFPG QGGP H I G AVA +A E++ Sbjct: 240 LILTRDA--ELGK-----------KLDKSVFPGTQGGPLEHVIAGKAVAFGEALKPEFQG 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV+ N+ A L ++G +VS GTDNHL+LV+L+ + G R ++++ V+I ANK Sbjct: 287 YSAQVIDNARTLANQLQTRGLKLVSDGTDNHLMLVDLRSVNMTGKRADQLVSEVNITANK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NTVP D S V G+R+G+PA+T+RG E +F ++ Sbjct: 347 NTVPFDPQSPFVTSGLRLGSPAMTTRGMGEAEFTEI 382
>Q92QU6:GLYA1_RHIME Serine hydroxymethyltransferase 1 - Rhizobium meliloti (Sinorhizobium| meliloti) Length = 431 Score = 345 bits (884), Expect = 5e-94 Identities = 201/455 (44%), Positives = 266/455 (58%), Gaps = 1/455 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L + DPEI IE E RQ +ELI SEN S +V++A GS+MTNKY+EGYPG RYYGG Sbjct: 14 LADSDPEIFGAIEKELGRQRHEIELIASENIVSRAVLEAQGSIMTNKYAEGYPGKRYYGG 73 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 +Y+D+AE L +RA + F ++ NVQP SGS N V+ ALL+P D M LDL Sbjct: 74 CQYVDIAEALAIERAKKLFGVN----FANVQPNSGSQMNQAVFLALLQPGDTFMGLDLNS 129 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y + E L+D D++ + A +PKLI+AG +AY Sbjct: 130 GGHLTHG-----SPVNMSGKWFNVVSYGVREDDHLLDMDEVARKAREQKPKLIIAGGTAY 184 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R++D+ R R+I D+ A L+ DMAHI+GLVA G PSPF + V TTTTHKSLRGPRG Sbjct: 185 SRIWDWKRFREIADEVGAWLMVDMAHIAGLVAGGQHPSPFPHCHVATTTTHKSLRGPRGG 244 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI +EI K KIN+AVFPGLQGGP H I AVAL +A ++ Sbjct: 245 MILTND--EEIAK-----------KINSAVFPGLQGGPLMHVIAAKAVALGEALQPSFKD 291 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV+ N+ AE+L + G DIVSGGTDNHL+LV+L+KK G R E L ++ NK Sbjct: 292 YAAQVVKNARTLAETLKANGLDIVSGGTDNHLMLVDLRKKNATGKRAEAALGRAYVTCNK 351 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D V G+R+G PA T+RGF E +F +V E ++ Sbjct: 352 NGIPFDPEKPFVTSGVRLGAPAGTTRGFKEAEFKEVGELI----------------VEVL 395 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIGF 1589 D + SD A A +R V + +FP G+ Sbjct: 396 DGLKAANSDEGNAAVEAGVREKVIKLTDRFPMYGY 430
>Q2FF15:GLYA_STAA3 Serine hydroxymethyltransferase - Staphylococcus aureus (strain| USA300) Length = 412 Score = 344 bits (882), Expect = 9e-94 Identities = 187/395 (47%), Positives = 254/395 (64%), Gaps = 2/395 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D IA+ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG E++ Sbjct: 8 DKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E++ RA F + VNVQP SGS AN VY L D ++ ++L HGGHL Sbjct: 68 DVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALGMGDTVLGMNLSHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F+ + Y +D+ T I+YD++ K A+ +PKLIVAGASAY+R Sbjct: 124 THG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAYSRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P EYAD VTTTTHK+LRGPRG MI Sbjct: 179 DFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGGMIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 K +++ I+ +FPG+QGGP H I AVA +A ++ YQ+Q Sbjct: 238 -------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFKTYQQQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKNTV 1316 V+ N+ AE+L ++G+ IVSGGTDNHLV V++K G+ G E+ L++V I NKNT+ Sbjct: 285 VVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITCNKNTI 344 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 P D V GIR+GTPA T+RGF E+ F +VA+ Sbjct: 345 PFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAK 379
>Q46HB6:GLYA_PROMT Serine hydroxymethyltransferase - Prochlorococcus marinus (strain| NATL2A) Length = 411 Score = 344 bits (882), Expect = 9e-94 Identities = 189/392 (48%), Positives = 251/392 (64%), Gaps = 1/392 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 DP IA +I E +RQ LELI SENF S +VM+A GSV+TNKY+EG P RYYGG EY+ Sbjct: 4 DPSIAKLINNELSRQETHLELIASENFASKAVMEAQGSVLTNKYAEGLPNKRYYGGCEYV 63 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D E L RA F + W NVQP SG+ ANF V+ +LLKP D IM +DL HGGHL Sbjct: 64 DGVEQLAIDRAKNLFGAN---WA-NVQPHSGAQANFAVFLSLLKPGDTIMGMDLSHGGHL 119 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ +F+T Y +D+ T ++D D + K A+ +PKLI+ G SAY R Sbjct: 120 THG-----SPVNVSGKWFKTCHYEVDKKTEMLDMDAIRKKAIENQPKLIICGFSAYPRKI 174 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R I D+ A LLAD+AHI+GLVA+G+ PSP Y DVVTTTTHK+LRGPRG +I Sbjct: 175 DFKAFRSIADEVNAYLLADIAHIAGLVASGLHPSPIPYCDVVTTTTHKTLRGPRGGLILS 234 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 + KEI K K++ AVFPG QGGP H I AVA K+A+ E++ Y ++ Sbjct: 235 KD--KEIGK-----------KLDKAVFPGTQGGPLEHVIAAKAVAFKEASAPEFKIYSQK 281 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V+SN+ + L +G IVS GTDNH+VL++L+ G+ G ++++ ++ I ANKNTVP Sbjct: 282 VISNAKVLSNQLQKRGISIVSKGTDNHIVLLDLRSIGMTGKVADQLVSDIKITANKNTVP 341 Query: 1320 GD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 D S V G+R+G+ ALT+RGF E+ F V Sbjct: 342 FDPESPFVTSGLRLGSAALTTRGFNEQAFGDV 373
>Q92XS8:GLYA2_RHIME Serine hydroxymethyltransferase 2 - Rhizobium meliloti (Sinorhizobium| meliloti) Length = 422 Score = 344 bits (882), Expect = 9e-94 Identities = 194/392 (49%), Positives = 240/392 (61%), Gaps = 1/392 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D IA I E RQ +ELI SEN S +V+ A GSVMTNKY+EGYPG RYYGG +Y+ Sbjct: 12 DSVIAGAIAREMGRQRSEIELIASENIVSPAVLAAQGSVMTNKYAEGYPGHRYYGGCQYV 71 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E +RA F+ VNVQP SG+ AN V ALLKP D M L L GGHL Sbjct: 72 DLVEAAAIERAGMLFDAS----FVNVQPHSGAQANGAVMLALLKPGDTFMGLSLAAGGHL 127 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG + +F + Y + ES LIDYD+LE A+ RPKLI+ G SAY RL Sbjct: 128 THGARPTMS-----GKWFNAVQYGVRESDCLIDYDELEVKAIATRPKLIITGGSAYPRLI 182 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R+R I D A ++ DMAH +GLVA GV P+P E AD+VTTTTHK+LRGPRG MI Sbjct: 183 DFKRIRAIADSVGAAMMVDMAHFAGLVAGGVHPNPVEIADIVTTTTHKTLRGPRGGMIL- 241 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 N Q D K+N+AVFPGLQGGP H I AVAL +A +R Y Q Sbjct: 242 ------TNNQ------DVAKKVNSAVFPGLQGGPLMHVIAAKAVALGEALEDNFRQYARQ 289 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 +++N+ A +LT +GYDIVSGGTD HL+LV+L+ KG+ G E+ L + NKN +P Sbjct: 290 MVANARALASALTERGYDIVSGGTDTHLILVDLRSKGVSGKDAEEALGRAGLTCNKNGIP 349 Query: 1320 GD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 D V GIR+GTPA TSRGF E +F +V Sbjct: 350 FDPAPPAVTSGIRLGTPAATSRGFREAEFNEV 381
>Q9HVI7:GLYA3_PSEAE Serine hydroxymethyltransferase 3 - Pseudomonas aeruginosa| Length = 417 Score = 343 bits (881), Expect = 1e-93 Identities = 187/397 (47%), Positives = 249/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L D E+ +E E RQ + +ELI SEN+TS +VM+A GSV+TNKY+EGYP RYYGG Sbjct: 8 LARYDAELFAAMEQEAQRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPHKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA + F D NVQP +GS AN VY ALL D I+ + L H Sbjct: 68 CEYVDIVEQLAIDRAKQLFGADY----ANVQPHAGSQANAAVYLALLSAGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG +S+ + + Y +D + GLIDYD++E+ AV +PK+IVAG SAY Sbjct: 124 GGHLTHG-----ASVSSSGKLYNAVQYGID-ANGLIDYDEVERLAVEHKPKMIVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ R R I DK A L DMAH++GLVAAGV P+P +ADVVTTTTHK+LRGPRG Sbjct: 178 SQVLDFARFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R + E K+N+AVFP QGGP H I AV K+A E++ Sbjct: 238 LILAR------------ANEEIEKKLNSAVFPSAQGGPLEHVIAAKAVCFKEALQPEFKT 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A+ +G+D+VSGGT NHL L++L K+ I G + L I NK Sbjct: 286 YQQQVLKNAQSMAQVFLDRGFDVVSGGTQNHLFLLSLIKQDITGKDADAALGRAFITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V G+R+GTPA+T+RGF E + ++A Sbjct: 346 NSVPNDPRSPFVTSGLRIGTPAVTTRGFKEAECRELA 382
>Q68W07:GLYA_RICTY Serine hydroxymethyltransferase - Rickettsia typhi| Length = 420 Score = 343 bits (880), Expect = 2e-93 Identities = 198/409 (48%), Positives = 255/409 (62%), Gaps = 5/409 (1%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 LN L +D EI +II+ EK RQ +ELI SENF S +V++A GS++TNKY+EGYP R Sbjct: 4 LNNNLYGMDKEIYEIIKNEKLRQNNVIELIASENFVSSAVLEAQGSILTNKYAEGYPSKR 63 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 +Y G + +D AE L +RA + FN NVQP SGS AN VY ALL+P D I+ + Sbjct: 64 FYNGCDEVDKAEVLAIERAKKLFNCKY----ANVQPHSGSQANQAVYLALLQPCDTILGM 119 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 L GGHL+HG + +F T+ Y +D+ T LIDYD++++ AVL PKL++AG Sbjct: 120 SLDSGGHLTHGAAPNIS-----GKWFNTVAYNVDKETYLIDYDEIKRLAVLHNPKLLIAG 174 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 SAY R D+ R R+I DK A L+AD+AHI+GLVA G SP YA VVT+TTHK+LRG Sbjct: 175 FSAYPRKIDFARFREIADKVGAYLMADIAHIAGLVATGEHQSPIPYAHVVTSTTHKTLRG 234 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG +I +EI K KIN+A+FPGLQGGP H I AVA + Sbjct: 235 PRGGLIL--SDYEEIGK-----------KINSALFPGLQGGPLMHVIAAKAVAFLENLQP 281 Query: 1116 EYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHI 1295 EY+ Y +QV+SN+ A SL +GYDI++GGTDNH+VLV+L+K GI G L+ I Sbjct: 282 EYKCYIKQVISNAKALAISLQERGYDILTGGTDNHIVLVDLRKDGITGKCAANSLDRAGI 341 Query: 1296 AANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFA----KVAEFFD 1427 NKN +P D S V GIR GT A T++GF E+DF VAE D Sbjct: 342 TCNKNAIPFDTTSPFVTSGIRFGTSACTTKGFKEKDFVLIGHMVAEILD 390
>Q7MXW0:GLYA_PORGI Serine hydroxymethyltransferase - Porphyromonas gingivalis| (Bacteroides gingivalis) Length = 426 Score = 343 bits (880), Expect = 2e-93 Identities = 189/403 (46%), Positives = 250/403 (62%), Gaps = 7/403 (1%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D I D+IE E RQ KG+ELI SENF S VMQA+GS MTNKY+EGYPG RYYGG E + Sbjct: 4 DSVIFDLIEKEHQRQLKGIELIASENFVSEQVMQAMGSCMTNKYAEGYPGKRYYGGCEVV 63 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D +E + R + + + W NVQP SG+ AN V A L+ D M L+L HGGHL Sbjct: 64 DQSEQIAIDRIKQLYGAE---WA-NVQPHSGAQANMAVLLACLEAGDTFMGLNLEHGGHL 119 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 SHG +++ I + + Y L E TG++DYD +EK A+ +PKLI+ G SAY+R + Sbjct: 120 SHG-----SLVNSSGILYRPIGYNLSEETGMVDYDHMEKMAIEHKPKLIIGGGSAYSREW 174 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 DY RMR+I DK A+L+ DMAH +GL+AAG++ +P +YA +VT+TTHK+LRGPRG +I Sbjct: 175 DYKRMREIADKVGALLMIDMAHPAGLIAAGLLENPVKYAHIVTSTTHKTLRGPRGGIILM 234 Query: 960 RKGVKEINKQGKEVKYDFEDKINA----AVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 K N GK+ K++A AVFPG+QGGP H I AVA +A ++ Sbjct: 235 GKDFD--NPWGKKTPKGEIKKMSALLDSAVFPGVQGGPLEHVIAAKAVAFGEALDPSFKE 292 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK--GIDGSRVEKVLENVHIAA 1301 YQ QV N+A A++ KGY ++SGGTDNH +L++L+ K + G EK L I Sbjct: 293 YQTQVKKNAAVLAQAFMDKGYKVISGGTDNHSMLIDLRPKFPELTGKVAEKALVAADITV 352 Query: 1302 NKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 NKN VP D SA G R+GTPA+T+RG E+ + E D Sbjct: 353 NKNMVPFDSRSAFQTSGFRVGTPAITTRGVKEDKMGYIVELID 395
>Q49Z60:GLYA_STAS1 Serine hydroxymethyltransferase - Staphylococcus saprophyticus subsp.| saprophyticus (strain ATCC 15305 / DSM 20229) Length = 412 Score = 343 bits (879), Expect = 2e-93 Identities = 186/399 (46%), Positives = 255/399 (63%), Gaps = 2/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +++ D EI ++I+ E RQ +ELI SENF S +VM+A GSV+TNKY+EGYP RYYGG Sbjct: 4 IQKQDKEIYEVIQNEFNRQNNNIELIASENFVSEAVMEAQGSVLTNKYAEGYPNRRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D++ETL RA + F + VNVQP SGS AN VY L+ D ++ ++L H Sbjct: 64 CEYVDVSETLAIDRAKKLFGAEH----VNVQPHSGSQANMAVYLVALEHGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ F+ + Y +D+ IDYD++ K A +PKLIVAGASAY Sbjct: 120 GGHLTHG-----APVNFSGQFYNFVEYGVDQENEQIDYDEVLKVAKEHKPKLIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R D+ R ++I D+ A L+ DMAHI+GLVA G+ P+P EYAD VTTTTHK+LRGPRG Sbjct: 175 SRTIDFKRFKEIADEVGAKLMVDMAHIAGLVAVGLHPNPVEYADFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI K +++ +I+ +FPG+Q GP H I AVA +A +++ Sbjct: 235 MIL--------------CKEEYKKQIDKTIFPGIQSGPLEHVIAAKAVAFGEALQDDFKV 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLK-KKGIDGSRVEKVLENVHIAAN 1304 YQ+QV+ N+ A +LT +G+ +VSGGTDNHLV V++K GI G E+ L+ + I N Sbjct: 281 YQQQVIQNAKTLANTLTDEGFRVVSGGTDNHLVAVDVKGSVGITGKVAEETLDAIGITCN 340 Query: 1305 KNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 KNT+P D V GIR+GTPA T+RGF E F +VA+ Sbjct: 341 KNTIPFDQEKPFVTSGIRLGTPAATTRGFDETAFEEVAK 379
>Q1RGX5:GLYA_RICBR Serine hydroxymethyltransferase - Rickettsia bellii (strain RML369-C)| Length = 420 Score = 343 bits (879), Expect = 2e-93 Identities = 192/399 (48%), Positives = 258/399 (64%), Gaps = 1/399 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N L+E+D I +II+ EK RQ +ELI SENF S +V++A GSV+TNKY+EGY G R+ Sbjct: 5 NNKLQEIDKGIFEIIKHEKTRQNSVIELIASENFVSPAVLEAQGSVLTNKYAEGYSGKRF 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 Y G E +D AE L +RA + FN NVQP SGS AN VY AL++P D ++ + Sbjct: 65 YNGCEEVDKAENLAIERAKKLFNCKY----ANVQPHSGSQANQAVYLALMQPGDTVLGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG T +S +F + Y +D+ T LIDYD++E+ A+L +PKL++AG Sbjct: 121 LDSGGHLTHG---STANMSGK--WFNAVSYSVDKETYLIDYDEVERLAILHKPKLLIAGF 175 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY R D+ + R+I DK A L+AD+AHI+GLVAAG SP +A +VT+TT+K+LRGP Sbjct: 176 SAYPRNLDFAKFREIADKVGAYLMADIAHIAGLVAAGEHQSPIPHAHIVTSTTNKTLRGP 235 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I +EI K KIN+A+FPGLQGGP H I AVA ++ E Sbjct: 236 RGGLIL--SNDEEIGK-----------KINSALFPGLQGGPLMHIIAAKAVAFLESLQPE 282 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 Y++Y +QV+ N+ A SL +GYDI++GGTDNH+VLV+L+K GI G L+ I Sbjct: 283 YKSYIKQVIINAKALAGSLQERGYDILTGGTDNHIVLVDLRKDGITGKIAANSLDRAGIT 342 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NKN +P D S + GIR+GTPA T+RGF E+DF V Sbjct: 343 CNKNAIPFDKTSPFITSGIRLGTPACTTRGFKEKDFVLV 381
>Q2RFW7:GLYA_MOOTA Serine hydroxymethyltransferase - Moorella thermoacetica (strain ATCC| 39073) Length = 416 Score = 343 bits (879), Expect = 2e-93 Identities = 188/399 (47%), Positives = 250/399 (62%), Gaps = 1/399 (0%) Frame = +3 Query: 234 EVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNE 413 +VDPEI + E RQ LELI SENF S +VM+A V+TNKY+EGYPG RYYGG E Sbjct: 8 KVDPEIVAAVRGELQRQRTHLELIASENFVSQAVMEAYSCVLTNKYAEGYPGKRYYGGCE 67 Query: 414 YIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGG 593 + D+ E L ++RA F + NVQP SGS AN VY A+L P D+ + ++L HGG Sbjct: 68 WADVVENLARERAKALFGAEH----ANVQPHSGSQANTAVYLAVLNPGDKALGMNLAHGG 123 Query: 594 HLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYAR 773 HL+HG +S ++ Y +D TG IDYD + + A RP+LIVAGASAY R Sbjct: 124 HLTHG-----SPVSLSGKYYNFCFYGVDAKTGRIDYDAVARIAREERPRLIVAGASAYPR 178 Query: 774 LYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMI 953 + D+ R R+I D+ A+L+ DMAHI+GLVAAG+ P+P YA VTTTTHK++RGPRG +I Sbjct: 179 VIDFARFREIADEVGALLMVDMAHIAGLVAAGIHPNPVPYAHFVTTTTHKTMRGPRGGII 238 Query: 954 FFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQ 1133 + ++ I+ AVFPG+QGGP H I AVALK+A E++ YQ Sbjct: 239 LTTR--------------EYARDIDKAVFPGVQGGPLMHVIAAKAVALKEAMLPEFKRYQ 284 Query: 1134 EQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNT 1313 EQ+++N+ A++L G+++VSGGTDNHL+LV+L+ K I G E +L +V I NKN Sbjct: 285 EQIVTNARTLADALMGYGFNLVSGGTDNHLMLVDLRNKNITGREAEDILASVQITVNKNA 344 Query: 1314 VPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 +P D V GIR+GT ALTSRG + +VA D Sbjct: 345 IPFDPQKPSVTSGIRLGTAALTSRGMDADAMVQVARAID 383
>Q7V4U3:GLYA_PROMM Serine hydroxymethyltransferase - Prochlorococcus marinus (strain MIT| 9313) Length = 429 Score = 342 bits (877), Expect = 3e-93 Identities = 193/402 (48%), Positives = 254/402 (63%), Gaps = 1/402 (0%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 +NA L + DP IA +I+ E+ RQ LELI SENFTS +VMQA GSV+TNKY+EG P R Sbjct: 9 INAALTDSDPAIAGLIDQERQRQETHLELIASENFTSQAVMQAQGSVLTNKYAEGLPHKR 68 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 YYGG E++D E L +RA F W NVQP SG+ ANF V+ ALL+P D IM + Sbjct: 69 YYGGCEHVDAIEELAIERAQRLFGA---AWA-NVQPHSGAQANFAVFLALLQPGDTIMGM 124 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 DL HGGHL+HG ++ +F+ + Y ++ + +D + + + A+ RP+LI+ G Sbjct: 125 DLSHGGHLTHG-----SPVNVSGKWFKVVHYGVERDSQQLDMEAVRQLALKERPQLIICG 179 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 SAY R D+ R I D+ A LLADMAHI+GLVAAGV PSP + DVVTTTTHK+LRG Sbjct: 180 YSAYPRTIDFAAFRSIADEVGAYLLADMAHIAGLVAAGVHPSPIAHCDVVTTTTHKTLRG 239 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG +I R DF K + AVFPG QGGP H I AVAL +A Sbjct: 240 PRGGLILCRDA-------------DFGRKFDKAVFPGSQGGPLEHVIAAKAVALGEALQP 286 Query: 1116 EYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHI 1295 E++ Y QV++N+ A + +G +VSGGTDNHLVL++L+ G+ G + ++ V+I Sbjct: 287 EFQVYSCQVVANAQVLAGRIQERGIAVVSGGTDNHLVLLDLRSIGMTGKVADLLVSEVNI 346 Query: 1296 AANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 ANKNTVP D S V G+R+GT ALT+RGF +E F +VA+ Sbjct: 347 TANKNTVPFDPESPFVTSGLRLGTAALTTRGFDDEAFREVAD 388
>Q6YR37:GLYA_ONYPE Serine hydroxymethyltransferase - Onion yellows phytoplasma| Length = 416 Score = 342 bits (877), Expect = 3e-93 Identities = 189/404 (46%), Positives = 259/404 (64%), Gaps = 4/404 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L++ D EI D+IE EK RQ + + LI SENF S +V+ A GS++TNKY+EGYP ARYY G Sbjct: 7 LKDQDQEIFDLIEQEKIRQKENILLIASENFVSQAVLDAQGSILTNKYAEGYPQARYYNG 66 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 + +D E + +RA + F NVQP SGS AN + ALLKP D+I+ L L Sbjct: 67 CKNVDQIEKIAIQRATKLFGAKY----ANVQPHSGSQANMGAFQALLKPGDKILGLSLMD 122 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG+ K+S F+E Y + T ++DYD++ K A+ +PKLI+AG SAY Sbjct: 123 GGHLTHGH-----KLSFSGGFYEAHFYNVHPQTEMLDYDEIRKVALKVKPKLIIAGYSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFE-YADVVTTTTHKSLRGPRG 944 ++ ++ + R+I D+ A L+AD+AHI+GLVA G+ P PFE ADVVT+T HK+LRGPRG Sbjct: 178 SKTINFKKFRQIADEVNAYLMADIAHIAGLVACGLHPCPFEANADVVTSTMHKTLRGPRG 237 Query: 945 AMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 +I K +E+ K KIN +FPG+QGGP HTI AVA ++A ++ Sbjct: 238 GLILTNK--EEVFK-----------KINRGIFPGIQGGPCIHTIAAKAVAFQEAMMPSFK 284 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKG--IDGSRVEKVLENVHIA 1298 YQ+QV+ N+ FA++ KGY IVSGGTDNHL L+++K K GS++ +LE ++I Sbjct: 285 EYQKQVIKNANTFAKAFQQKGYRIVSGGTDNHLFLIDVKHKNPEFTGSKIANMLEKINIV 344 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 NKNT+P D V GIR+GTPA+T+ GF E DF VA+ D Sbjct: 345 VNKNTIPFDQEKPFVTSGIRIGTPAMTTVGFRENDFILVADLMD 388
>Q3J9K8:GLYA_NITOC Serine hydroxymethyltransferase - Nitrosococcus oceani (strain ATCC| 19707 / NCIMB 11848) Length = 417 Score = 342 bits (877), Expect = 3e-93 Identities = 185/393 (47%), Positives = 250/393 (63%), Gaps = 1/393 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D E+ + E RQ + +ELI SEN+ S V++A GSV+TNKY+EGYPG RYYGG EY+ Sbjct: 12 DEELETALTNEARRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGGCEYV 71 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+AE L +RA F D NVQP SGS AN ALL P D +M L L HGGHL Sbjct: 72 DVAERLAIERAKILFEADY----ANVQPHSGSQANAAACLALLAPGDTLMGLSLAHGGHL 127 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG K++ F + + ++ TGLIDYD++E+ A RPKLI+AG +AY+R+ Sbjct: 128 THG-----AKVNFSGQIFNAVQFGVNADTGLIDYDEVEQLAKAHRPKLIIAGFTAYSRIV 182 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R R I D A LLAD+AH++G++AAG+ P+P + ADV T+TTHK+LRGPR +I Sbjct: 183 DWQRFRAIADGVGAYLLADIAHLAGMIAAGIYPNPVQIADVTTSTTHKTLRGPRSGLI-- 240 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 + K E+ E K+N+ VFPG+QGGP H + AVA K+A ++ YQ Q Sbjct: 241 ------LAKANPEI----EKKLNSKVFPGIQGGPLMHVVAAKAVAFKEAMEPAFKDYQRQ 290 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V+ N+ AE++ S+GY IVSGGTD+HL LV+L KG+ G + L +I NKNTVP Sbjct: 291 VIRNAQAMAEAIQSRGYKIVSGGTDSHLFLVDLVAKGLTGKAADAALGRANITVNKNTVP 350 Query: 1320 GD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 D S V GIR+G+PA+T+RGF E + ++A Sbjct: 351 NDPQSPFVTSGIRIGSPAMTTRGFKEAEICELA 383
>Q2W4T2:GLYA_MAGMM Serine hydroxymethyltransferase - Magnetospirillum magneticum (strain| AMB-1 / ATCC 700264) Length = 427 Score = 342 bits (877), Expect = 3e-93 Identities = 198/452 (43%), Positives = 262/452 (57%), Gaps = 1/452 (0%) Frame = +3 Query: 225 PLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYG 404 PL E DPE+ I E RQ +ELI SEN S +V++A GSVMTNKY+EGYPG RYYG Sbjct: 13 PLSERDPEVFAAITQELKRQQDQIELIASENIVSRAVLEAQGSVMTNKYAEGYPGKRYYG 72 Query: 405 GNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLP 584 G E++D+AE+L RA + F NVQP SGS AN V+ ALL+P D IM + L Sbjct: 73 GCEFVDIAESLAISRACQIFGCSY----ANVQPSSGSQANQGVFMALLQPGDTIMGMSLA 128 Query: 585 HGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASA 764 GGHL+HG + +F+ + Y + + ID+ ++E+ A RPKLI+AG SA Sbjct: 129 AGGHLTHGAAPNQS-----GKWFKAVQYGVRQQDSQIDFAEVEELARTHRPKLIIAGGSA 183 Query: 765 YARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRG 944 Y R D+ R RKI D+ A + DMAH +GLVA GV P+P +A VVTTTTHK+LRGPRG Sbjct: 184 YPRTIDFARFRKIADEVGAFFMVDMAHFAGLVAGGVYPNPLPHAHVVTTTTHKTLRGPRG 243 Query: 945 AMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 MI D KIN+A+FPG+QGGP H I G AVA +A E++ Sbjct: 244 GMILSNDA-------------DIGKKINSAIFPGIQGGPLMHVIAGKAVAFGEALKPEFK 290 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAAN 1304 Y +QV+ N+ A++L +G DIVSGGTD+HL+LV+L+ K + G E LE+ + N Sbjct: 291 LYAKQVVDNARALADTLVRRGLDIVSGGTDSHLMLVDLRPKKLTGKAAEASLEHAGMTCN 350 Query: 1305 KNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKL 1481 KN +P D + G+R+GTPA T+RGF E+F KV E G L Sbjct: 351 KNGIPFDPEKPTITSGVRLGTPAATTRGFGVEEFKKVGELI---------------GDVL 395 Query: 1482 KDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 A + +S A A+ R +V E ++FP Sbjct: 396 DGLAANPEDNS---AAEARARAEVAELCRRFP 424
>Q71WN9:GLYA_LISMF Serine hydroxymethyltransferase - Listeria monocytogenes serotype 4b| (strain F2365) Length = 413 Score = 342 bits (877), Expect = 3e-93 Identities = 182/396 (45%), Positives = 253/396 (63%), Gaps = 1/396 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L++ D E+ D I+LE RQ +ELI SENF S VM+A+GSV+TNKY+EGYPG RYYGG Sbjct: 4 LQKQDKEVFDAIKLELGRQRANIELIASENFVSEQVMEAMGSVLTNKYAEGYPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E L + RA + F + NVQP SG+ AN VY +L+P D ++ ++L H Sbjct: 64 CEFVDIVEDLARDRAKKLFGAEY----ANVQPHSGAQANMAVYHTVLEPGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + + Y + E T IDYD + ++A+ +PK+IVAGASAY Sbjct: 120 GGHLTHG-----SPVNFSGVLYNFVEYGVREDTKEIDYDIVREAALKHKPKMIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + R+I D+ A L+ DMAHI+GLVAAG+ +P YAD TTTTHK+LRGPRG Sbjct: 175 PRKIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPYADFTTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI K ++E K+N ++FPG+QGGP H I AVA +A E+ A Sbjct: 235 MIL--------------AKAEWEQKLNKSIFPGIQGGPLMHVIAAKAVAFGEALQPEFTA 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y EQ++ NS + AE+L + +++GG+DNHL+L++LK G+ G EKVL+ V I NK Sbjct: 281 YCEQIIRNSKKLAETLQANDVAVLTGGSDNHLLLIDLKPLGLTGKAAEKVLDEVGITVNK 340 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NT+P + S V GIR+G A+T+RGF E KV Sbjct: 341 NTIPFETESPFVTSGIRVGVAAVTTRGFDEVAIEKV 376
>Q31FS6:GLYA_THICR Serine hydroxymethyltransferase - Thiomicrospira crunogena (strain| XCL-2) Length = 423 Score = 342 bits (876), Expect = 4e-93 Identities = 184/402 (45%), Positives = 251/402 (62%), Gaps = 1/402 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N + D +AD + E RQ +ELI SEN+TS VM+A GSV+TNKY+EGYP RY Sbjct: 5 NMTIAGYDDALADAMNAEAQRQEDHIELIASENYTSPRVMEAQGSVLTNKYAEGYPNKRY 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG E++D+ E L RA E F D NVQP SGS AN VY ALL+P D ++ + Sbjct: 65 YGGCEHVDVVEQLAIDRAKELFGADY----ANVQPHSGSQANAPVYMALLEPGDTVLGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG +S + + Y L+ TG+IDYD++E+ A +PK+I+AG Sbjct: 121 LAHGGHLTHG-----SHVSFSGKMYNAVQYGLNPETGVIDYDEVERLAKEHKPKMIIAGF 175 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY+++ D+ + R+I D A L+ DMAH++GLVAAG P+P + ADV TTTTHK+LRGP Sbjct: 176 SAYSQVVDWQKFREIADAVGAYLMVDMAHVAGLVAAGEYPNPVQIADVTTTTTHKTLRGP 235 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 R +I + K E+ E K+N+A+FPG QGGP H I AVA K+A E Sbjct: 236 RSGLI--------LAKSNPEI----EKKLNSAIFPGAQGGPLMHVIAAKAVAFKEAMEPE 283 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y +QV N+ A+ ++G+D+VS GT+NHL LV+ ++G+ G V+ L HI Sbjct: 284 FKTYAKQVKVNAKAMADVFMARGFDVVSKGTENHLFLVSFIEQGLTGKLVDAALGEAHIT 343 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NKN+VP D +S V GIR+GT A T+RGF EED +A + Sbjct: 344 INKNSVPNDPMSPFVTSGIRVGTAASTTRGFTEEDSKNLASW 385
>Q7N216:GLYA_PHOLL Serine hydroxymethyltransferase - Photorhabdus luminescens subsp.| laumondii Length = 417 Score = 342 bits (876), Expect = 4e-93 Identities = 185/393 (47%), Positives = 247/393 (62%), Gaps = 1/393 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 DPE+ +E E RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG EY+ Sbjct: 12 DPELWQAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYV 71 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E L RA F D NVQP SGS AN VY ALL+P D I+ ++L HGGHL Sbjct: 72 DVVEQLAIDRAKALFGADY----ANVQPHSGSQANAAVYMALLQPGDTILGMNLAHGGHL 127 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ + +PY +DES G IDYD + A +PK+I+ G SAY+ + Sbjct: 128 THG-----SPVNFSGKLYNVVPYGIDES-GKIDYDDIAAQAEKHQPKMIIGGFSAYSGVV 181 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ +MR+I D A L DMAH++GL+AAGV P+P +A +VTTTTHK+L GPRG +I Sbjct: 182 DWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHIVTTTTHKTLAGPRGGLILA 241 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 + G +E+ K K+N++VFPG QGGP H I G AVALK+A E++AYQ Q Sbjct: 242 KGGDEELYK-----------KLNSSVFPGCQGGPLMHVIAGKAVALKEAMEPEFKAYQHQ 290 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V N+ E ++GY +VSG T+NHL L++L K I G + L +I NKN+VP Sbjct: 291 VADNAKAMVEVFLARGYKVVSGSTENHLFLLDLVDKNITGKDADAALGRANITVNKNSVP 350 Query: 1320 GD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 D S V G+R+GTPA+T RGF + + ++A Sbjct: 351 NDPKSPFVTSGVRIGTPAITRRGFKQAEARELA 383
>Q6D246:GLYA1_ERWCT Serine hydroxymethyltransferase 1 - Erwinia carotovora subsp.| atroseptica (Pectobacterium atrosepticum) Length = 417 Score = 342 bits (876), Expect = 4e-93 Identities = 185/397 (46%), Positives = 251/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D ++ +E E RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDADLWQAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA F D NVQP SGS ANF VYTALL+P D I+ ++L H Sbjct: 68 CEYVDIVEQLAIDRAKALFGADY----ANVQPHSGSQANFAVYTALLQPGDTILGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ ++ +PY +DES G IDYD++ + A +PK+IV G SAY Sbjct: 124 GGHLTHG-----SPVNLSGKLYKVIPYGIDES-GKIDYDEMAELARTHQPKMIVGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A L DMAH++GL+AA V P+P +A +VTTTTHK+L GPRG Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLIAADVYPNPVPHAHIVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +++ K K+N+AVFPG QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGDEDLYK-----------KLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKV 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ E S+G+++VSG T NHL L++L K + G + L +I NK Sbjct: 287 YQQQVAKNAKAMVEVFLSRGFNVVSGATSNHLFLLDLVSKNLTGKEADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+GTPA T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGIRIGTPAATRRGFKEAEVRELA 383
>Q481S6:GLYA2_COLP3 Serine hydroxymethyltransferase 2 - Colwellia psychrerythraea (strain| 34H / ATCC BAA-681) (Vibrio psychroerythus) Length = 417 Score = 341 bits (875), Expect = 6e-93 Identities = 189/397 (47%), Positives = 250/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N + D I +E E RQ +ELI SEN+TS VMQA GS +TNKY+EGYPG RY Sbjct: 5 NDQIAGFDDSIWQAMEQEDKRQQDHVELIASENYTSARVMQAQGSQLTNKYAEGYPGKRY 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG E++D+ E L RA E F D NVQP SGS AN V+ ALLKP + ++ + Sbjct: 65 YGGCEHVDVIEQLAIDRAKELFGADY----ANVQPHSGSQANAAVFMALLKPGETVLGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG K+S + + Y L+E+TG IDY+++E+ A +PK+I+AG Sbjct: 121 LAHGGHLTHG-----SKVSFSGKIYNAVQYGLNEATGEIDYEEVERLAKEHQPKMIIAGF 175 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY+R+ D+ R R I D A L DMAH++GLVAAG+ P+P ADVVTTTTHK+LRGP Sbjct: 176 SAYSRVVDWQRFRDIADSIGAWLFVDMAHVAGLVAAGLYPNPVPIADVVTTTTHKTLRGP 235 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I + KQ E+ K+N+AVFP QGGP H I A+ K+A + Sbjct: 236 RGGLI--------LAKQNDEL----AKKLNSAVFPAGQGGPLMHVIAAKAICFKEALGEG 283 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 Y YQ+QV+ N+ A++ ++GY++VSGGTDNHL L++L KGI G + L +I Sbjct: 284 YVEYQQQVIDNAREMAKTFQTRGYNVVSGGTDNHLFLLDLIDKGITGKDADAALGRANIT 343 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFA 1406 NKN+VP D S V G+R+GTPA+TSRGF E+ A Sbjct: 344 VNKNSVPNDPQSPFVTSGLRIGTPAITSRGFGLEEAA 380
>Q4FUZ8:GLYA_PSYAR Serine hydroxymethyltransferase - Psychrobacter arcticum| Length = 418 Score = 341 bits (874), Expect = 7e-93 Identities = 184/397 (46%), Positives = 252/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +++ DP +A + E RQ +ELI SEN+ S +VM+A G+ +TNKY+EGYPG RYYGG Sbjct: 7 IKDFDPVLAKAMAAESVRQENHIELIASENYCSQAVMEAQGTDLTNKYAEGYPGKRYYGG 66 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E L RA E F + VNVQP SGS AN V+ ALL+ +D ++ + L Sbjct: 67 CEHVDVVEQLAIDRAKELFGAEY----VNVQPHSGSQANSAVFLALLEANDTVLGMSLDA 122 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG I+ + + + Y L E TGLIDYDQ+E A +PK+I+AG SAY Sbjct: 123 GGHLTHGAH-----INFSGLNYNAVQYGLVEGTGLIDYDQVESLAKEHKPKMIIAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ R R+I D+ A LL DMAH++GL+A GV PSP +ADVVTTTTHK+LRGPR Sbjct: 178 SQVVDWARFREIADEVGAYLLVDMAHVAGLIAGGVYPSPVPFADVVTTTTHKTLRGPRSG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI R K K K+N+AVFPG QGGP H I A+ K+A ++ Sbjct: 238 MILARD-----EKLAK--------KLNSAVFPGNQGGPLMHVIAAKAICFKEALENNFKT 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ A+ + +GY+I+SGGT+NHL+L++L K+ + G +K L + HI NK Sbjct: 285 YQQQVVKNAQAMAKVIQERGYEIISGGTENHLMLISLVKQEMTGKEADKWLGDAHITVNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N VP D S V GIR+GTPA+T+RGF E +A Sbjct: 345 NAVPNDPKSPFVTSGIRIGTPAITTRGFNEAQAGALA 381
>Q7VDS8:GLYA_PROMA Serine hydroxymethyltransferase - Prochlorococcus marinus| Length = 419 Score = 340 bits (873), Expect = 1e-92 Identities = 189/402 (47%), Positives = 253/402 (62%), Gaps = 1/402 (0%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 +N+ L DP+I+ +I E RQ LELI SENF S +VM+A GSV+TNKY+EG P R Sbjct: 4 INSDLRNTDPDISFLINQELLRQQTHLELIASENFASEAVMEAQGSVLTNKYAEGLPNKR 63 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 YYGG E+ID E L RA FN + W NVQP SG+ ANF V+ ALL P D IM + Sbjct: 64 YYGGCEHIDAIEQLAITRAQTLFNAE---WA-NVQPHSGAQANFAVFLALLNPGDTIMGM 119 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 DL HGGHL+HG ++ +F + Y +D++T +++++Q+ + A+ RPKLI+ G Sbjct: 120 DLSHGGHLTHG-----SPVNVSGKWFNAIHYGVDQTTKVLNFEQIRQVALKNRPKLIICG 174 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 SAY R D+ R I D+ A LLAD+AHI+GLVA G P+P Y DVVTTTTHK+LRG Sbjct: 175 FSAYPRTIDFKAFRSIADEIDAYLLADIAHIAGLVACGAHPNPVPYCDVVTTTTHKTLRG 234 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG +I R KE K + + AVFPG QGGP H I AVA +A Sbjct: 235 PRGGLILCRD--KEFGK-----------RFDKAVFPGNQGGPLEHVIAAKAVAFGEALKP 281 Query: 1116 EYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHI 1295 E++ Y QV+SN+ A+ + +G IVS GTDNH+VL++L+ + G + + ++ V+I Sbjct: 282 EFKTYTFQVISNAKALAKRIQERGISIVSEGTDNHIVLLDLRSIEMTGKKADSLISEVNI 341 Query: 1296 AANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 ANKNTVP D S V G+R+GT ALT+RGF E+ F +VA+ Sbjct: 342 TANKNTVPFDPESPFVTSGLRLGTAALTTRGFTEKAFIEVAD 383
>Q8Y4B2:GLYA_LISMO Serine hydroxymethyltransferase - Listeria monocytogenes| Length = 413 Score = 340 bits (873), Expect = 1e-92 Identities = 181/396 (45%), Positives = 252/396 (63%), Gaps = 1/396 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L++ D E+ D I+LE RQ +ELI SENF S VM+A+GSV+TNKY+EGYPG RYYGG Sbjct: 4 LQKQDKEVFDAIKLELGRQRANIELIASENFVSEQVMEAMGSVLTNKYAEGYPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E L + RA + F + NVQP SG+ AN VY +L+P D ++ ++L H Sbjct: 64 CEFVDIVEDLARDRAKKLFGAEY----ANVQPHSGAQANMAVYHTVLEPGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + + Y + E T IDYD + ++A+ +PK+IVAGASAY Sbjct: 120 GGHLTHG-----SPVNFSGVLYNFVEYGVREDTKEIDYDIVREAALKHKPKMIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + R+I D+ A L+ DMAHI+GLVAAG+ +P YAD TTTTHK+LRGPRG Sbjct: 175 PRKIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPYADFTTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI K ++E K+N ++FPG+QGGP H I AVA +A E+ Sbjct: 235 MIL--------------AKAEWEQKLNKSIFPGIQGGPLMHVIAAKAVAFGEALQPEFTT 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y EQ++ NS + AE+L + +++GG+DNHL+L++LK G+ G EKVL+ V I NK Sbjct: 281 YCEQIIRNSKKLAETLQANDVAVLTGGSDNHLLLIDLKPLGLTGKAAEKVLDEVGITVNK 340 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NT+P + S V GIR+G A+T+RGF E KV Sbjct: 341 NTIPFETESPFVTSGIRVGVAAVTTRGFDEVAIEKV 376
>Q927V4:GLYA_LISIN Serine hydroxymethyltransferase - Listeria innocua| Length = 413 Score = 340 bits (873), Expect = 1e-92 Identities = 181/396 (45%), Positives = 253/396 (63%), Gaps = 1/396 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L++ D E+ D I+LE RQ +ELI SENF S VM+A+GSV+TNKY+EGYPG RYYGG Sbjct: 4 LQKQDKEVFDAIKLELGRQRANIELIASENFVSEQVMEAMGSVLTNKYAEGYPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E L + RA + F + NVQP SG+ AN VY +L+P D ++ ++L H Sbjct: 64 CEFVDIVEDLARDRAKKLFGAEY----ANVQPHSGAQANMAVYHTVLEPGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + + Y + E T IDY+ + ++A+ +PK+IVAGASAY Sbjct: 120 GGHLTHG-----SPVNFSGVLYNFVEYGVREDTKEIDYEIVREAALKHKPKMIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + R+I D+ A L+ DMAHI+GLVAAG+ +P YAD TTTTHK+LRGPRG Sbjct: 175 PRKIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPYADFTTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI K ++E K+N ++FPG+QGGP H I AVA +A E+ A Sbjct: 235 MIL--------------AKAEWEQKLNKSIFPGIQGGPLMHVIAAKAVAFGEALQPEFTA 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y EQ++ NS + AE+L + +++GG+DNHL+L++LK G+ G EKVL+ V I NK Sbjct: 281 YCEQIIRNSKKLAETLQANDVAVLTGGSDNHLLLIDLKPLGLTGKAAEKVLDEVGITVNK 340 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NT+P + S V GIR+G A+T+RGF E KV Sbjct: 341 NTIPFETESPFVTSGIRVGVAAVTTRGFDEVAIEKV 376
>Q72CT0:GLYA_DESVH Serine hydroxymethyltransferase - Desulfovibrio vulgaris (strain| Hildenborough / ATCC 29579 / NCIMB 8303) Length = 412 Score = 340 bits (873), Expect = 1e-92 Identities = 197/447 (44%), Positives = 262/447 (58%), Gaps = 1/447 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 DPE+ I LE RQ LELI SENF S +V QA GSV+T+KY+EGYPG RYYGG E++ Sbjct: 8 DPEVGKAIILEIERQTGKLELIASENFVSAAVRQAQGSVLTHKYAEGYPGKRYYGGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+AE + +RA F + NVQP SGS AN VY A LKP D I+ ++L HGGHL Sbjct: 68 DIAENIAIERARTIFGCEY----ANVQPHSGSQANMGVYFACLKPGDTILGMNLSHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ F + Y +++ TG IDY+Q+ A +P LIVAGASAY R Sbjct: 124 THG-----SPVNFSGRLFNVVFYGVEKETGRIDYEQVAALAREHKPSLIVAGASAYPRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R R I D+ A L+ DMAHI+GLVAAG PSP ++A TTTTHK+LRGPRG MI Sbjct: 179 DFARFRAIADEVGAKLMVDMAHIAGLVAAGYHPSPVQHAHYTTTTTHKTLRGPRGGMILS 238 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 + D +N+ +FPG+QGGP H I AVA +A ++ YQ+Q Sbjct: 239 TE--------------DNGKTLNSQIFPGIQGGPLMHVIAAKAVAFGEALRPAFKEYQKQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V+ N+A A LT+ G+D+VSGGTDNHL+LV+L K + G E L+ I NKNTVP Sbjct: 285 VVDNAAALAGVLTAAGFDLVSGGTDNHLMLVDLTSKDVTGKDAEIALDKAGITVNKNTVP 344 Query: 1320 GDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFVA 1496 + S V G+R+GTPALT+RG + KV G + D +A Sbjct: 345 FETRSPFVTSGVRLGTPALTTRGMKAAEMEKV-------------------GGWIVDAIA 385 Query: 1497 TLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 +++ +A++ +VE +A+QFP Sbjct: 386 NTTNET----RLAEISREVERFARQFP 408
>P39148:GLYA_BACSU Serine hydroxymethyltransferase - Bacillus subtilis| Length = 415 Score = 340 bits (873), Expect = 1e-92 Identities = 177/384 (46%), Positives = 248/384 (64%), Gaps = 1/384 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D ++ + I+ E+ RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG E++ Sbjct: 8 DEQVFNAIKNERERQQTKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E + + RA E F + VNVQP SG+ AN VY +L+ D ++ ++L HGGHL Sbjct: 68 DVVEDIARDRAKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ + + + Y +D+ T IDYD + + A+ +PKLIVAGASAY R Sbjct: 124 THG-----SPVNFSGVQYNFVEYGVDKETQYIDYDDVREKALAHKPKLIVAGASAYPRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + R+I D+ A + DMAHI+GLVAAG+ P+P YAD VTTTTHK+LRGPRG MI Sbjct: 179 DFKKFREIADEVGAYFMVDMAHIAGLVAAGLHPNPVPYADFVTTTTHKTLRGPRGGMILC 238 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 R+ +F KI+ ++FPG+QGGP H I AV+ + +++ Y + Sbjct: 239 RE--------------EFGKKIDKSIFPGIQGGPLMHVIAAKAVSFGEVLQDDFKTYAQN 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V+SN+ R AE+LT +G +VSGGTDNHL+LV+L+ G+ G E VL+ + I +NKN +P Sbjct: 285 VISNAKRLAEALTKEGIQLVSGGTDNHLILVDLRSLGLTGKVAEHVLDEIGITSNKNAIP 344 Query: 1320 GD-VSAMVPGGIRMGTPALTSRGF 1388 D V GIR+GT A+TSRGF Sbjct: 345 YDPEKPFVTSGIRLGTAAVTSRGF 368
>Q3KDV1:GLYA1_PSEPF Serine hydroxymethyltransferase 1 - Pseudomonas fluorescens (strain| PfO-1) Length = 412 Score = 340 bits (873), Expect = 1e-92 Identities = 183/397 (46%), Positives = 252/397 (63%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ DP IA +I+ E+ RQ LELI SEN+ S V+QA GS++TNKY+EGYPG RYYGG Sbjct: 3 LQNFDPAIARLIDRERNRQETHLELIASENYVSEEVLQAQGSLLTNKYAEGYPGRRYYGG 62 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 + +D E L +RA + F + VNVQP SGS AN V+ A+L+P DRI+ + L H Sbjct: 63 CKVVDEIENLAIERARKLFGCEY----VNVQPHSGSQANQAVFLAVLEPGDRILGMSLAH 118 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ FF+ Y L++ + +DYDQ+E A RPK+I+AGASAY Sbjct: 119 GGHLTHG-----ASVNFSGKFFQAFTYGLEKDSETLDYDQMEDLAREHRPKMIIAGASAY 173 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R+ D+ R RKICD+ A L+ DMAH +GL+AAGV PSP AD +T+TTHK+LRGPRG Sbjct: 174 SRVIDFPRFRKICDEIGAYLMVDMAHYAGLIAAGVYPSPVGIADFITSTTHKTLRGPRGG 233 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I K ++ ++ +FP QGGP H I AVA +A E++ Sbjct: 234 LIL--------------AKAEYAAVLDKTIFPVYQGGPLMHVIAAKAVAFNEALGDEFKH 279 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ++V++N+ A+ LT +G +VSGGTD H+ L++L+ I G E +LE+ HI NK Sbjct: 280 YQQRVINNARTMADVLTRRGLRVVSGGTDCHMFLLDLRAMNITGKDAEALLESAHITLNK 339 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N +P D + GIR+GTPALT+RGF E + A+VA Sbjct: 340 NAIPDDPQKPAITSGIRIGTPALTTRGFGEAECAEVA 376
>Q47MD6:GLYA_THEFY Serine hydroxymethyltransferase - Thermobifida fusca (strain YX)| Length = 423 Score = 340 bits (872), Expect = 1e-92 Identities = 191/407 (46%), Positives = 252/407 (61%), Gaps = 6/407 (1%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 L L ++DPE+A ++ E ARQ LE+I SENF +V++A G+V+TNKY+EGYPG R Sbjct: 8 LTQSLAQLDPEVAAAVDAELARQRDTLEMIASENFAPRAVLEAQGTVLTNKYAEGYPGRR 67 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 YYGG E++D+ E L RA F + NVQP SG+ AN VY ALL+P D I+ L Sbjct: 68 YYGGCEHVDVIEQLAIDRAKALFGAEH----ANVQPHSGAQANTAVYFALLQPGDTILGL 123 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 DL HGGHL+HG +I+ + Y + ES GLIDYD++E A +PKLI+AG Sbjct: 124 DLAHGGHLTHGM-----RINYSGKILNAVAYHVRESDGLIDYDEVEALAKEHQPKLIIAG 178 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 SAY R D+ R R+I D+ A+L+ DMAH +GLVAAG+ P+P YADVVTTTTHK+L G Sbjct: 179 WSAYPRQLDFARFREIADQTGALLMVDMAHFAGLVAAGLHPNPVPYADVVTTTTHKTLGG 238 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG +I K + KIN+AVFPG+QGGP H I AVALK A ++ Sbjct: 239 PRGGLIL--------------AKEELGKKINSAVFPGMQGGPLQHVIAAKAVALKVAASE 284 Query: 1116 EYRAYQEQVMSNSARFAESLT-----SKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVL 1280 E+ Q + +S + AE LT G +++GGTD HLVLV+L ++G E L Sbjct: 285 EFAERQRRTLSGAKILAERLTQPDAAEAGIRVLTGGTDVHLVLVDLVNSELNGKEAEDRL 344 Query: 1281 ENVHIAANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 + I N+N VP D MV G+R+GTPAL +RGF + DFA+VA+ Sbjct: 345 HEIGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDADFAEVAD 391
>Q6G3L3:GLYA_BARHE Serine hydroxymethyltransferase - Bartonella henselae (Rochalimaea| henselae) Length = 437 Score = 340 bits (872), Expect = 1e-92 Identities = 193/464 (41%), Positives = 272/464 (58%), Gaps = 1/464 (0%) Frame = +3 Query: 201 TWPKQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEG 380 T + N L+ VD I D I E RQ +ELI SEN S +V++A GSV+TNKY+EG Sbjct: 8 TQKRFFNDNLQTVDVAIFDAIRGEFERQQHEIELIASENIVSRAVLEAQGSVLTNKYAEG 67 Query: 381 YPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHD 560 YPG RYYGG +++D+ E L +RA + F D NVQ SGS N V+ ALLKP D Sbjct: 68 YPGKRYYGGCQFVDVIENLAIERAKKLFGAD----FANVQANSGSQMNQAVFLALLKPGD 123 Query: 561 RIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPK 740 M LDL GGHL+HG ++ +F+++ Y + + L+D + +E+ A +PK Sbjct: 124 TFMGLDLNSGGHLTHG-----SSVNMSGKWFKSISYGVRKEDQLLDMEAVERLAKEHKPK 178 Query: 741 LIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTH 920 LI+AG SAY+RL+D+ + R+I D+ A LL DM+HI+GLVA GV PSP +A +VTTTTH Sbjct: 179 LIIAGGSAYSRLWDWKKFREIADEIGAYLLVDMSHIAGLVAGGVHPSPVPHAHIVTTTTH 238 Query: 921 KSLRGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALK 1100 KSLRGPRG +I + KIN+A+FPGLQGGP H I AVA + Sbjct: 239 KSLRGPRGGLILTNDEI-------------LAKKINSAIFPGLQGGPLMHVIAAKAVAFE 285 Query: 1101 QATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVL 1280 +A ++ Y V++N+ A++L S G+DIVSGGTDNHL+LV+L+ K + G E L Sbjct: 286 EALQPVFKDYSANVVANAKTLAKTLQSNGFDIVSGGTDNHLLLVDLRSKKVTGKCAELAL 345 Query: 1281 ENVHIAANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXX 1457 HI NKN++P D+ + + GIR+G+PA T+RGF E +F ++A Sbjct: 346 GRAHITCNKNSIPFDLETPFITSGIRLGSPAATTRGFAENEFIEIAHMI----------- 394 Query: 1458 XXXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIGF 1589 +++ D + +SD + A +R VE+ +FP + Sbjct: 395 -----SEILDNLGMAKSDEDNSAVEMVVRKKVEDMTNKFPLYSY 433
>Q7MAR0:GLYA_WOLSU Serine hydroxymethyltransferase - Wolinella succinogenes| Length = 416 Score = 340 bits (871), Expect = 2e-92 Identities = 197/455 (43%), Positives = 274/455 (60%), Gaps = 1/455 (0%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 +N LE D EI D+I E RQ LE+I SENFT +VM+A+GSV+TNKY+EGYP R Sbjct: 1 MNYALETNDKEIFDLIHEELDRQNTHLEMIASENFTFPAVMEAMGSVLTNKYAEGYPYKR 60 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 YYGG E++D E + +RA + F NVQP +GS AN VY ALLKP+D+I+ + Sbjct: 61 YYGGCEFVDRVEEIAIERAKKLFGCG----FANVQPHAGSQANVAVYNALLKPYDKILGM 116 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 DL HGGHL+HG K+S +++ Y + E G I+YD++E+ A + +P++IV G Sbjct: 117 DLSHGGHLTHG-----AKVSVTGQTYQSFFYGV-ELDGYINYDKVEEIAKIVKPQMIVCG 170 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 SAYAR D+ R R+I D A+LL D+AH++GL+ AG P+PF + +VTTTTHK+LRG Sbjct: 171 FSAYARELDFKRFREIADSVGALLLGDVAHVAGLIVAGEYPNPFPHCHIVTTTTHKTLRG 230 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG MI +EI K KI+ AVFPG+QGGP H I AV + Sbjct: 231 PRGGMILTND--EEIAK-----------KIDKAVFPGMQGGPLMHVIAAKAVGFGENLKP 277 Query: 1116 EYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHI 1295 E++ Y +QV +N+ A+ L ++GY +VSGGTDNHL+LV+L K G ++ L I Sbjct: 278 EWKEYAKQVKANAKVLAKVLMARGYTLVSGGTDNHLILVSLLDKEFSGKDADRALGEAGI 337 Query: 1296 AANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXG 1472 NKNTVPG+ S V G+R+G+ ALT+RG E++F +A Sbjct: 338 TVNKNTVPGETRSPFVTSGVRIGSAALTARGMREKEFEFIA------------------- 378 Query: 1473 TKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 TK+ D + D N A+ A+++ ++ E+AK FP Sbjct: 379 TKIADVL----DDVNNAAKHAEIKKEIAEFAKGFP 409
>Q8XJ32:GLYA_CLOPE Serine hydroxymethyltransferase - Clostridium perfringens| Length = 410 Score = 340 bits (871), Expect = 2e-92 Identities = 178/401 (44%), Positives = 252/401 (62%), Gaps = 1/401 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE D +IA +++ EK RQ +ELI SENF S +VM+A+GS +TNKY+EGYP RYYGG Sbjct: 6 LEREDEQIAHLVQKEKERQENSIELIASENFVSKAVMEAMGSYLTNKYAEGYPSKRYYGG 65 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 +D E L ++R + F + NVQP SGS AN VY ++L+P D ++ +DL H Sbjct: 66 CHVVDEVEDLARERVKKLFGAEH----ANVQPHSGSQANMAVYFSILEPGDTVLGMDLSH 121 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ F + Y +D+ T I+Y+ + + A+ +PKLIVAGASAY Sbjct: 122 GGHLTHG-----SSVNFSGRLFNFVSYGVDKETETINYETVRELALKHKPKLIVAGASAY 176 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R+ D+ +R+I D+ A L+ D+AHI+GLVA G+ PSP YAD VT+TTHK+LRGPRG Sbjct: 177 SRIIDFKTLREIADEVGAYLMVDIAHIAGLVATGLHPSPVPYADFVTSTTHKTLRGPRGG 236 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I K F ++ +FPG+QGGP H I AV K+A ++ Sbjct: 237 LIL--------------CKEKFAKVLDKNIFPGIQGGPLMHIIAAKAVCFKEALEPSFKT 282 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y EQV+ N+ AE+L + G+ +VS GTDNHL+LV+L K I G E +L+++ I NK Sbjct: 283 YMEQVVKNAHVLAEALEAYGFKLVSNGTDNHLILVDLTNKDITGKDAEILLDSIGITLNK 342 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 NTVP + S V G+R+GTPA+T+RGF EE+ ++A + Sbjct: 343 NTVPNETRSPFVTSGVRIGTPAITTRGFKEEEMKEIASIIN 383
>Q2S9R4:GLYA2_HAHCH Serine hydroxymethyltransferase 2 - Hahella chejuensis (strain KCTC| 2396) Length = 418 Score = 340 bits (871), Expect = 2e-92 Identities = 196/447 (43%), Positives = 257/447 (57%), Gaps = 1/447 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 DP++ ++ E RQ + +ELI SEN+TS VM+A GS +TNKY+EGYP RYYGG EY+ Sbjct: 12 DPDLWTAMQGETQRQEEHIELIASENYTSPRVMEAQGSALTNKYAEGYPNKRYYGGCEYV 71 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E L RA E F D NVQP SGS AN VY AL KP D I+ + L HGGHL Sbjct: 72 DVVEQLAIDRAKELFGADY----ANVQPHSGSQANAAVYMALCKPGDVILGMSLAHGGHL 127 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG +S ++ + Y L+ TG IDY+++ K A +PK+IVAG SAY+R+ Sbjct: 128 THG-----ASVSFSGRIYKAVQYGLNPETGEIDYEEVAKLARENKPKMIVAGFSAYSRVI 182 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R R I D+ A L DMAHI+GLVAAGV PSP + ADV TTTTHK+L GPRG +I Sbjct: 183 DWERFRAIADEVGAYLFVDMAHIAGLVAAGVYPSPVQIADVTTTTTHKTLGGPRGGLIL- 241 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 + + E K+N AVFP QGGP H I AV K+A T E++ YQ Q Sbjct: 242 -----------AKANEELEKKLNFAVFPESQGGPLMHVIAAKAVCFKEAMTDEFKQYQAQ 290 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V+ N+ A++ +GYDIVSGGTD+HL LV+L KK I G + L +I NKN VP Sbjct: 291 VVKNARVMADTFIQRGYDIVSGGTDDHLFLVDLIKKDITGKDADAALGRANITVNKNAVP 350 Query: 1320 GDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFVA 1496 D S V G+R+GTPA+T RG E + +L D++ Sbjct: 351 NDPRSPFVTSGLRIGTPAITRRGMGEVE-----------------------AKELTDWIC 387 Query: 1497 TLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 + D + I +++ V E K+FP Sbjct: 388 DVLDDIENEETIQRVKQQVLELCKKFP 414
>Q9KTG1:GLYA1_VIBCH Serine hydroxymethyltransferase 1 - Vibrio cholerae| Length = 416 Score = 340 bits (871), Expect = 2e-92 Identities = 187/399 (46%), Positives = 248/399 (62%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + DPE+ I+ E RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDPELYAAIQEETLRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D AE L RA + F + NVQP SGS AN VY ALL P D ++ + L H Sbjct: 68 CEYVDKAEALAIDRACQLFGCEY----ANVQPHSGSQANSAVYMALLNPGDTVLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DE+ G I+YD++E A+ +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKHYNVIPYGIDEA-GQINYDEMEALALEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ RMR+I DK A L DMAH++GL+AAGV PSP +A VVTTTTHK+L GPRG Sbjct: 178 SQIVDWKRMREIADKVGAYLFVDMAHVAGLIAAGVYPSPVPFAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I G +E+ K K+N+AVFPG QGGP H I AVA K+A E++ Sbjct: 238 LILSNAG-EEMYK-----------KLNSAVFPGGQGGPLMHVIAAKAVAFKEAMEPEFKE 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ +V+ N+ +GY IVS T+NHL LV+L K I G + L +I NK Sbjct: 286 YQARVVKNAKAMVAQFQERGYKIVSNSTENHLFLVDLIDKNITGKEADAALGAANITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 N+VP D S V GIR+GTPA+T RGF E+D +A + Sbjct: 346 NSVPNDPRSPFVTSGIRVGTPAITRRGFTEQDAKDLANW 384
>Q8CRN3:GLYA_STAES Serine hydroxymethyltransferase - Staphylococcus epidermidis (strain| ATCC 12228) Length = 412 Score = 339 bits (870), Expect = 2e-92 Identities = 181/399 (45%), Positives = 254/399 (63%), Gaps = 2/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +E+ D + D I+ E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 4 IEKKDKVVYDAIQKEFQRQNSNIELIASENFVSQAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E++ +RA F + VNVQP SGS AN VY L+ D ++ ++L H Sbjct: 64 CEHVDVTESIAIERAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ F+ + Y +D+ LI+YD++ + A+ +PKLIVAGASAY Sbjct: 120 GGHLTHG-----ATVNFSGKFYHFVEYGVDQENELINYDEVRRLAIEHQPKLIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P EYAD VTTTTHK+LRGPRG Sbjct: 175 SRTIDFKKFKEIADEVGAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI K +++ I+ +FPG+QGGP H I AVA +A +++ Sbjct: 235 MIL--------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALNDDFKD 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAAN 1304 YQ QV+ N+ A++L +G+ +VSGGTDNHLV V++K + G E+ L+ V I N Sbjct: 281 YQNQVIKNAQALAQTLIEEGFRVVSGGTDNHLVAVDVKGSINMTGKLAEETLDKVGITCN 340 Query: 1305 KNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 KNT+P D V G+R+GTPA T+RGF E F +VA+ Sbjct: 341 KNTIPFDKEKPFVTSGVRLGTPAATTRGFDESAFVEVAK 379
>Q5HMB0:GLYA_STAEQ Serine hydroxymethyltransferase - Staphylococcus epidermidis (strain| ATCC 35984 / RP62A) Length = 412 Score = 339 bits (870), Expect = 2e-92 Identities = 181/399 (45%), Positives = 254/399 (63%), Gaps = 2/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +E+ D + D I+ E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 4 IEKKDKVVYDAIQKEFQRQNSNIELIASENFVSQAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E++ +RA F + VNVQP SGS AN VY L+ D ++ ++L H Sbjct: 64 CEHVDVTESIAIERAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ F+ + Y +D+ LI+YD++ + A+ +PKLIVAGASAY Sbjct: 120 GGHLTHG-----ATVNFSGKFYHFVEYGVDQENELINYDEVRRLAIEHQPKLIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P EYAD VTTTTHK+LRGPRG Sbjct: 175 SRTIDFKKFKEIADEVGAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI K +++ I+ +FPG+QGGP H I AVA +A +++ Sbjct: 235 MIL--------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALNDDFKD 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAAN 1304 YQ QV+ N+ A++L +G+ +VSGGTDNHLV V++K + G E+ L+ V I N Sbjct: 281 YQNQVIKNAQALAQTLIEEGFRVVSGGTDNHLVAVDVKGSINMTGKLAEETLDKVGITCN 340 Query: 1305 KNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 KNT+P D V G+R+GTPA T+RGF E F +VA+ Sbjct: 341 KNTIPFDKEKPFVTSGVRLGTPAATTRGFDESAFVEVAK 379
>Q65DW5:GLYA_BACLD Serine hydroxymethyltransferase - Bacillus licheniformis (strain DSM| 13 / ATCC 14580) Length = 415 Score = 339 bits (870), Expect = 2e-92 Identities = 180/392 (45%), Positives = 252/392 (64%), Gaps = 1/392 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D ++ I+ E+ RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG E++ Sbjct: 8 DEQVFSAIQDERKRQQSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+AE + + RA + F + VNVQP SG+ AN VY +L+ D ++ ++L HGGHL Sbjct: 68 DVAEDIARDRAKQIFGAEH----VNVQPHSGAQANMAVYFTILEHGDTVLGMNLAHGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ + + + Y +D+ T IDY+ + + A+ +PKLIVAGASAY R Sbjct: 124 THG-----SPVNFSGVQYNFVEYGVDKETQYIDYEDVREKALKHKPKLIVAGASAYPRTI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + R+I D+ A ++ DMAHI+GLVAAG+ P+P YAD VTTTTHK+LRGPRG MI Sbjct: 179 DFKKFREIADEVGAYVMVDMAHIAGLVAAGLHPNPVPYADFVTTTTHKTLRGPRGGMILC 238 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 R+ +F +I+ ++FPG+QGGP H I AV+ +A E++ Y + Sbjct: 239 RE--------------EFAKQIDKSIFPGIQGGPLMHVIAAKAVSFGEALKDEFKTYAQN 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 V++N+ R AE+L +G ++VSGGTDNHLVLV+L+ GI G E VL+ V I NKN +P Sbjct: 285 VINNAKRLAETLKKEGIELVSGGTDNHLVLVDLRSLGITGKVAENVLDEVGITVNKNAIP 344 Query: 1320 GD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 D V GIR+GT A+TSRGF E +V Sbjct: 345 YDPEKPFVTSGIRVGTAAVTSRGFDLEAIEEV 376
>Q47WY2:GLYA4_COLP3 Serine hydroxymethyltransferase 4 - Colwellia psychrerythraea (strain| 34H / ATCC BAA-681) (Vibrio psychroerythus) Length = 417 Score = 339 bits (870), Expect = 2e-92 Identities = 189/397 (47%), Positives = 248/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N + D I +E E RQ +ELI SEN+TS VMQA GS +TNKY+EGYPG RY Sbjct: 5 NDQIAGFDDSIWQAMEQEDKRQQDHVELIASENYTSARVMQAQGSQLTNKYAEGYPGKRY 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG E++D+ E L RA E F D NVQP SGS AN V+ ALLKP + ++ + Sbjct: 65 YGGCEHVDVIEQLAIDRAKELFGADY----ANVQPHSGSQANAAVFMALLKPGETVLGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG K+S + + Y L+E TG IDYD++ + A +PK+I+AG Sbjct: 121 LAHGGHLTHG-----SKVSFSGKIYNAVQYGLNEVTGEIDYDEVARLAKEHQPKMIIAGF 175 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY+R+ D+ R R I D A L DMAH++GLVAAG+ P+P ADVVTTTTHK+LRGP Sbjct: 176 SAYSRVVDWQRFRDIADSIGAWLFVDMAHVAGLVAAGLYPNPVPIADVVTTTTHKTLRGP 235 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I + KQ E+ K+N+AVFP QGGP H I A+ K+A + Sbjct: 236 RGGLI--------LAKQNDEL----AKKLNSAVFPAGQGGPLMHVIAAKAICFKEALGEG 283 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 Y YQ+QV+ N+ A++ ++GY++VSGGTDNHL L++L KGI G + L +I Sbjct: 284 YVEYQQQVIDNAREMAKTFQTRGYNVVSGGTDNHLFLLDLIDKGITGKDADAALGRANIT 343 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFA 1406 NKN+VP D S V G+R+GTPA+TSRGF E+ A Sbjct: 344 VNKNSVPNDPQSPFVTSGLRIGTPAITSRGFGLEEAA 380
>Q39J72:GLYA3_BURS3 Serine hydroxymethyltransferase 3 - Burkholderia sp. (strain 383)| (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) Length = 415 Score = 339 bits (870), Expect = 2e-92 Identities = 195/451 (43%), Positives = 264/451 (58%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + VDPEI IE E RQ +ELI SEN+TS +VM A GS +TNKY+EGYPG RYYGG Sbjct: 9 IANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L R + F + NVQP SGS AN V+ A+LKP D IM + L H Sbjct: 69 CEYVDVVEQLAIDRVKQLFGAE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y L+E+ IDY+ E+ A +PKLIVAGASA+ Sbjct: 125 GGHLTHG-----SPVNMSGKWFNVVSYGLNENED-IDYEAAEQLAQEHKPKLIVAGASAF 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + D+ R+ KI A L+ DMAH +GL+AAGV P+P +AD VTTTTHKSLRGPRG Sbjct: 179 SLKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +K ++E IN+A+FPG+QGGP H I G AVA K+A + E++A Sbjct: 239 VIL--------------MKAEYEKPINSAIFPGIQGGPLMHVIAGKAVAFKEALSPEFKA 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQE+V+ N+ AE+L +G IVSG T++H++LV+L+ K I G E L HI NK Sbjct: 285 YQEKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D V G+R+G+PA+T+RGF + +V Sbjct: 345 NAIPNDPEKPFVTSGVRLGSPAMTTRGFGPAEAEQVG----------------------- 381 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 + +A + + A I ++R V E K+FP Sbjct: 382 NLIADVLDNPEDAATIERVRAQVAELTKRFP 412
>Q87RR2:GLYA1_VIBPA Serine hydroxymethyltransferase 1 - Vibrio parahaemolyticus| Length = 416 Score = 339 bits (869), Expect = 3e-92 Identities = 186/399 (46%), Positives = 247/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ I+ E RQ + +ELI SEN+TS VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELFAAIQEETLRQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D AE L RA + F + NVQP SGS AN VY ALL P D ++ + L H Sbjct: 68 CEYVDKAEQLAIDRACKLFGCEY----ANVQPHSGSQANSAVYMALLNPGDTVLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DE+ G I+YD++E+ A+ +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKHYNVIPYGIDEA-GQINYDEMEQLALEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ RMR+I DK A L DMAH++GL+AAG P+P +A VVTTTTHK+L GPRG Sbjct: 178 SQIVDWKRMREIADKVDAYLFVDMAHVAGLIAAGEYPTPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I G D K+N+AVFPG QGGP H I G AVA K+A E++A Sbjct: 238 LILSNAG------------EDMYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEAMEPEFKA 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ +V+ N+ +GY IVS GT+NHL LV+L K I G + L +I NK Sbjct: 286 YQARVVKNAKAMVGQFQERGYKIVSNGTENHLFLVDLIDKDITGKDADAALGAANITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 N+VP D S V GIR+GTPA+T RGF EED +A + Sbjct: 346 NSVPNDPRSPFVTSGIRVGTPAITRRGFTEEDAKDLANW 384
>Q83BT3:GLYA_COXBU Serine hydroxymethyltransferase - Coxiella burnetii| Length = 419 Score = 338 bits (868), Expect = 4e-92 Identities = 183/399 (45%), Positives = 250/399 (62%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +E D E+A I E+ RQ +ELI SEN+ S V++ GSV+TNKY+EGYPG RYYGG Sbjct: 8 VESFDSELAGAIRDERRRQEHHVELIASENYVSPRVLELQGSVLTNKYAEGYPGRRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L RA E F D NVQP SGS AN Y AL+ P D ++A+DL H Sbjct: 68 CEFVDIAEQLAIDRAKELFGADY----ANVQPHSGSQANAEAYMALMNPGDTLLAMDLSH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG +S F++ + Y L+ + G IDY+Q + A +PK+I+AG SA+ Sbjct: 124 GGHLTHG-----SPVSFSGKFYKAVHYGLN-AHGDIDYEQAAQLAQEHKPKVILAGFSAF 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ R R+I D A + D+AH++GLVAAGV PSP + ADV TTTTHK+LRGPR Sbjct: 178 SGIVDWQRFREIADSVNAYFMTDIAHVAGLVAAGVYPSPVQIADVTTTTTHKTLRGPRAG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + + E ++N+AVFPG QGGP H I AVA K+A E++ Sbjct: 238 LILAKANP------------ELEKRLNSAVFPGSQGGPLMHIIAAKAVAFKEAMQPEFKT 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +Q++ N+ AE + +GY IVSGGT NHL LV+L K I G E L +I NK Sbjct: 286 YAQQILKNAKAMAEVMKERGYTIVSGGTQNHLFLVSLLDKNISGKEAEAALGRANITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NTVPG+ S V G+R+GTPA+T+RGF E++ +++A + Sbjct: 346 NTVPGETRSPFVTSGLRIGTPAITTRGFKEKEASQLAHW 384
>Q391K1:GLYA2_BURS3 Serine hydroxymethyltransferase 2 - Burkholderia sp. (strain 383)| (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) Length = 415 Score = 338 bits (868), Expect = 4e-92 Identities = 197/455 (43%), Positives = 263/455 (57%), Gaps = 5/455 (1%) Frame = +3 Query: 237 VDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEY 416 VDPE+ IE E RQ +ELI SEN+TS +VM A GS +TNKY+EGYPG RYYGG EY Sbjct: 12 VDPELYAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEY 71 Query: 417 IDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGH 596 +D+ E L R + F + NVQP SGS AN V+ A+LKP D IM + L HGGH Sbjct: 72 VDVVEQLAIDRVKQLFGAE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGH 127 Query: 597 LSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARL 776 L+HG ++ +F + Y L+E+ IDY+ E+ A +PKLIVAGASA++ Sbjct: 128 LTHG-----SPVNMSGKWFNVVSYGLNENED-IDYEAAEQLAQEHKPKLIVAGASAFSLK 181 Query: 777 YDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIF 956 D+ R+ KI A L+ DMAH +GL+AAGV P+P +AD VTTTTHKSLRGPRG +I Sbjct: 182 IDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVIL 241 Query: 957 FRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQE 1136 +K ++E IN+A+FPG+QGGP H I G AVA K+A + E++AYQE Sbjct: 242 --------------MKAEYEKPINSAIFPGIQGGPLMHVIAGKAVAFKEALSPEFKAYQE 287 Query: 1137 QVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTV 1316 +V+ N+ AE+L +G IVSG T++H++LV+L+ K I G E L HI NKN + Sbjct: 288 KVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGAAHITVNKNAI 347 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFV 1493 P D V G+R+G+PA+T+RGF G K + V Sbjct: 348 PNDPEKPFVTSGVRLGSPAMTTRGF---------------------------GVKEAEIV 380 Query: 1494 ATLQSD----SNIQAEIAKLRHDVEEYAKQFPTIG 1586 L +D A + ++R V E K+FP G Sbjct: 381 GNLIADVLEAPEDAATLERVRGQVAELTKRFPVYG 415
>Q31RK5:GLYA_SYNP7 Serine hydroxymethyltransferase - Synechococcus sp. (strain PCC 7942)| (Anacystis nidulans R2) Length = 427 Score = 338 bits (867), Expect = 5e-92 Identities = 191/398 (47%), Positives = 250/398 (62%), Gaps = 1/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L + DP IA II E RQ + LELI SENF S +VM A GSV+TNKY+EG P RYYGG Sbjct: 9 LAQGDPAIAAIIGRELQRQQEHLELIASENFASPAVMAAQGSVLTNKYAEGLPSKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D AE L +RA E F NVQP SG+ ANF V+ LL+P D + +DL H Sbjct: 69 CEFVDQAEELAIERAKELFGAAH----ANVQPHSGAQANFAVFLTLLQPGDTFLGMDLSH 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F Y ++ T +DYD + + A+ RPKLI+ G SAY Sbjct: 125 GGHLTHG-----SPVNVSGKWFNAGHYGVNRETERLDYDAIRELALQHRPKLIICGYSAY 179 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + R+I D+ A LLADMAHI+GLVAAG+ PSP + DVVTTTTHK+LRGPRG Sbjct: 180 PRTIDFAKFREIADEVGAYLLADMAHIAGLVAAGLHPSPIPHCDVVTTTTHKTLRGPRGG 239 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R E+ K K++ +VFPG QGGP H I AVA +A E++ Sbjct: 240 LILTRDA--ELGK-----------KLDKSVFPGTQGGPLEHVIAAKAVAFGEALRPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV++N+ A L ++G IVS GTDNHL+LV+L+ G+ G + ++ +V+I ANK Sbjct: 287 YSAQVIANAQALARQLQARGLKIVSDGTDNHLLLVDLRSIGMTGKVADLLVSDVNITANK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 NTVP D S V GIR+GT A+T+RGF E +FA VA+ Sbjct: 347 NTVPFDPESPFVTSGIRLGTAAMTTRGFKEAEFAIVAD 384
>Q5N2P9:GLYA_SYNP6 Serine hydroxymethyltransferase - Synechococcus sp. (strain ATCC| 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) Length = 427 Score = 338 bits (867), Expect = 5e-92 Identities = 191/398 (47%), Positives = 250/398 (62%), Gaps = 1/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L + DP IA II E RQ + LELI SENF S +VM A GSV+TNKY+EG P RYYGG Sbjct: 9 LAQGDPAIAAIIGRELQRQQEHLELIASENFASPAVMAAQGSVLTNKYAEGLPSKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D AE L +RA E F NVQP SG+ ANF V+ LL+P D + +DL H Sbjct: 69 CEFVDQAEELAIERAKELFGAAH----ANVQPHSGAQANFAVFLTLLQPGDTFLGMDLSH 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F Y ++ T +DYD + + A+ RPKLI+ G SAY Sbjct: 125 GGHLTHG-----SPVNVSGKWFNAGHYGVNRETERLDYDAIRELALQHRPKLIICGYSAY 179 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + R+I D+ A LLADMAHI+GLVAAG+ PSP + DVVTTTTHK+LRGPRG Sbjct: 180 PRTIDFAKFREIADEVGAYLLADMAHIAGLVAAGLHPSPIPHCDVVTTTTHKTLRGPRGG 239 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R E+ K K++ +VFPG QGGP H I AVA +A E++ Sbjct: 240 LILTRDA--ELGK-----------KLDKSVFPGTQGGPLEHVIAAKAVAFGEALRPEFKT 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV++N+ A L ++G IVS GTDNHL+LV+L+ G+ G + ++ +V+I ANK Sbjct: 287 YSAQVIANAQALARQLQARGLKIVSDGTDNHLLLVDLRSIGMTGKVADLLVSDVNITANK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 NTVP D S V GIR+GT A+T+RGF E +FA VA+ Sbjct: 347 NTVPFDPESPFVTSGIRLGTAAMTTRGFKEAEFAIVAD 384
>Q667X1:GLYA_YERPS Serine hydroxymethyltransferase - Yersinia pseudotuberculosis| Length = 417 Score = 338 bits (866), Expect = 6e-92 Identities = 182/397 (45%), Positives = 249/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D ++ +E E RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDADLWRAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA F D NVQP SGS AN VY+ALLKP D ++ ++L H Sbjct: 68 CEYVDVVEQLAIDRAKALFGADY----ANVQPHSGSQANVAVYSALLKPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DES G IDY+ L + A + +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGIDES-GQIDYEDLARQAEIHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A DMAH++GLVAAGV P+P +A +VTTTTHK+L GPRG Sbjct: 178 SGIVDWAKMREIADSIDAWFFVDMAHVAGLVAAGVYPNPVPHAHIVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +++ K K+N++VFPG QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGDEDLYK-----------KLNSSVFPGNQGGPLMHVIAGKAVALKEAMEPEFKI 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ +GY +VSGGTDNHL L++L K I G + L +I NK Sbjct: 287 YQQQVAKNAKAMVAVFLERGYKVVSGGTDNHLFLLDLVDKDITGKDADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V G+R+G+PA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGVRIGSPAITRRGFKEAESRELA 383
>Q8ZCR1:GLYA_YERPE Serine hydroxymethyltransferase - Yersinia pestis| Length = 417 Score = 338 bits (866), Expect = 6e-92 Identities = 182/397 (45%), Positives = 249/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D ++ +E E RQ + +ELI SEN+TS VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDADLWRAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L RA F D NVQP SGS AN VY+ALLKP D ++ ++L H Sbjct: 68 CEYVDVVEQLAIDRAKALFGADY----ANVQPHSGSQANVAVYSALLKPGDTVLGMNLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DES G IDY+ L + A + +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGIDES-GQIDYEDLARQAEIHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ +MR+I D A DMAH++GLVAAGV P+P +A +VTTTTHK+L GPRG Sbjct: 178 SGIVDWAKMREIADSIDAWFFVDMAHVAGLVAAGVYPNPVPHAHIVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +++ K K+N++VFPG QGGP H I G AVALK+A E++ Sbjct: 238 LILAKGGDEDLYK-----------KLNSSVFPGNQGGPLMHVIAGKAVALKEAMEPEFKI 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV N+ +GY +VSGGTDNHL L++L K I G + L +I NK Sbjct: 287 YQQQVAKNAKAMVAVFLERGYKVVSGGTDNHLFLLDLVDKDITGKDADAALGRANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V G+R+G+PA+T RGF E + ++A Sbjct: 347 NSVPNDPKSPFVTSGVRIGSPAITRRGFKEAESRELA 383
>Q7MN19:GLYA1_VIBVY Serine hydroxymethyltransferase 1 - Vibrio vulnificus (strain YJ016)| Length = 416 Score = 338 bits (866), Expect = 6e-92 Identities = 185/399 (46%), Positives = 246/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ I+ E RQ + +ELI SEN+TS VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELFAAIQEETLRQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D AE L RA + F + NVQP SGS AN VY ALL P D ++ + L H Sbjct: 68 CEYVDKAEALAIDRACQLFGCEY----ANVQPHSGSQANSAVYMALLNPGDTVLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DE+ G I+YD++E A+ +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKHYNVIPYGIDEA-GQINYDEMETLALEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ RMR+I DK A L DMAH++GL+AAG P+P +A VVTTTTHK+L GPRG Sbjct: 178 SQIVDWKRMREIADKVDAYLFVDMAHVAGLIAAGEYPTPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I G D K+N+AVFPG QGGP H I G AVA K+A E++A Sbjct: 238 LILSNAG------------EDMYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEAMEPEFKA 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ +V+ N+ +GY IVS GT+NHL LV+L K I G + L +I NK Sbjct: 286 YQARVVKNAKAMVAQFQERGYKIVSNGTENHLFLVDLIDKDITGKDADAALGAANITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 N+VP D S V GIR+GTPA+T RGF E D ++A + Sbjct: 346 NSVPNDPRSPFVTSGIRVGTPAITRRGFTEADAKELANW 384
>Q8DFC9:GLYA1_VIBVU Serine hydroxymethyltransferase 1 - Vibrio vulnificus| Length = 416 Score = 338 bits (866), Expect = 6e-92 Identities = 185/399 (46%), Positives = 246/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ I+ E RQ + +ELI SEN+TS VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELFAAIQEETLRQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D AE L RA + F + NVQP SGS AN VY ALL P D ++ + L H Sbjct: 68 CEYVDKAEALAIDRACQLFGCEY----ANVQPHSGSQANSAVYMALLNPGDTVLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DE+ G I+YD++E A+ +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKHYNVIPYGIDEA-GQINYDEMETLALEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ RMR+I DK A L DMAH++GL+AAG P+P +A VVTTTTHK+L GPRG Sbjct: 178 SQIVDWKRMREIADKVDAYLFVDMAHVAGLIAAGEYPTPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I G D K+N+AVFPG QGGP H I G AVA K+A E++A Sbjct: 238 LILSNAG------------EDMYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEAMEPEFKA 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ +V+ N+ +GY IVS GT+NHL LV+L K I G + L +I NK Sbjct: 286 YQARVVKNAKAMVAQFQERGYKIVSNGTENHLFLVDLIDKDITGKDADAALGAANITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 N+VP D S V GIR+GTPA+T RGF E D ++A + Sbjct: 346 NSVPNDPRSPFVTSGIRVGTPAITRRGFTEADAKELANW 384
>Q5E706:GLYA_VIBF1 Serine hydroxymethyltransferase - Vibrio fischeri (strain ATCC 700601| / ES114) Length = 416 Score = 337 bits (865), Expect = 8e-92 Identities = 183/397 (46%), Positives = 249/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D ++ I+ E RQ + +ELI SEN+TS VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDADLFAAIQEETVRQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D ETL +RA E F + NVQP SGS AN VY ALL D ++ + L H Sbjct: 68 CEYVDKVETLAIERACELFGAEY----ANVQPHSGSQANNAVYMALLNAGDTVLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DE+ G IDY+++E AV +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIIPYGIDEN-GQIDYEEMEALAVEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ RMR+I DK A DMAH++GL+AAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SQVCDWARMREIADKVGAYFFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +G D K+N+AVFPG QGGP H I G AVA K+A E++ Sbjct: 238 LILSNEG------------EDLYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEALEPEFKE 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ +V++N+ ++GY+IVSG T+NHL LV+L K I G + L + +I NK Sbjct: 286 YQARVVANAKAMVAEFLARGYNIVSGSTENHLFLVDLIDKDITGKEADAALGSANITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+G+P++T RGF EED +A Sbjct: 346 NSVPNDPRSPFVTSGIRIGSPSITRRGFTEEDAKNLA 382
>Q8EM73:GLYA_OCEIH Serine hydroxymethyltransferase - Oceanobacillus iheyensis| Length = 411 Score = 337 bits (865), Expect = 8e-92 Identities = 176/397 (44%), Positives = 256/397 (64%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +++ D E+ + ++ EK RQ +ELI SENF + +VM A+GS++TNKY+EGYPG RYYGG Sbjct: 4 VKQADTEVFEAMQAEKNRQQDKIELIASENFVTKAVMDAMGSILTNKYAEGYPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E L + RA E F D NVQP SG+ AN VY+A+L+P D ++ ++L H Sbjct: 64 CEHVDVVENLARDRAKELFGADH----ANVQPHSGAQANMAVYSAVLEPGDTVLGMNLNH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + Y +D+ T +DYD + + A +PKLIVAGASAY Sbjct: 120 GGHLTHG-----SPVNFSGQLYNFVDYGVDKETEQLDYDAVLEKAKEVKPKLIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R ++ + R+I D A L+ DMAHI+GLVA G +P +AD VTTTTHK+LRGPRG Sbjct: 175 SRSINFAKFREIADAVDAYLMVDMAHIAGLVATGEHENPVPHADFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI K +F K++ A+FPG+QGGP H I AV+ K+A + +++A Sbjct: 235 MIL--------------CKEEFAKKVDKAIFPGIQGGPLMHVIAAKAVSFKEALSDDFKA 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +Q+++N+ E+L +G IVSGGTDNHL+L+++ + G EK L+++ I NK Sbjct: 281 YSKQIVANAKLLGEALNKEGIRIVSGGTDNHLLLLDVTPLQLTGKVAEKALDDIGITTNK 340 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 NT+P D S V GIR+GT A+T+RGF EE+ ++A Sbjct: 341 NTIPFDQESPFVTSGIRIGTAAVTTRGFGEEEMKEIA 377
>Q38WJ7:GLYA_LACSS Serine hydroxymethyltransferase - Lactobacillus sakei subsp. sakei| (strain 23K) Length = 415 Score = 337 bits (865), Expect = 8e-92 Identities = 187/398 (46%), Positives = 252/398 (63%), Gaps = 2/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L + DP I D+I+ E+ RQ +ELI SEN S +V +A GSV+TNKY+EGYP R+YGG Sbjct: 2 LAKTDPVINDLIKQEENRQRHNIELIASENIVSGAVQEAQGSVLTNKYAEGYPNKRFYGG 61 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EYID ETL +RA E F D VNVQP SGS AN VY ALL+P D+I+ ++L Sbjct: 62 CEYIDQIETLAIERAKELFGADH----VNVQPHSGSQANMAVYQALLEPGDKILGMNLTD 117 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG + ++ Y + ++ +DY L A PK+IVAGASAY Sbjct: 118 GGHLTHG-----SPFNFSGQLYDFYSYGVADTNEQLDYASLAAKAQEVHPKMIVAGASAY 172 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R D+ R+R+I D+ A L+ DMAHI+GLVA GV PSP YADVVTTTTHK+LRGPRG Sbjct: 173 SRTIDFPRLREIADQVGAYLMIDMAHIAGLVATGVHPSPVPYADVVTTTTHKTLRGPRGG 232 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI K ++ I++A+FPG+QGGP H I AVA +A E+ A Sbjct: 233 MIL--------------CKAEYAKAIDSAIFPGIQGGPLEHVIAAKAVAFGEALQPEFTA 278 Query: 1128 YQEQVMSNSARFAESL-TSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAAN 1304 Y +Q+++N+ A S +VSGGTDNHL+L++L G++G ++ +L++VHI N Sbjct: 279 YTKQIVANAQAMAAVFDQSDLVRVVSGGTDNHLMLLDLTNSGLNGKELQNLLDSVHITVN 338 Query: 1305 KNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 KNT+P + +S GIR+GTPA+TSRGF E+D ++A Sbjct: 339 KNTIPFEKLSPFKTSGIRIGTPAITSRGFKEKDCEQIA 376
>Q8G1F1:GLYA_BRUSU Serine hydroxymethyltransferase - Brucella suis| Length = 438 Score = 337 bits (865), Expect = 8e-92 Identities = 187/399 (46%), Positives = 246/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 NA LE++DPEI I E RQ +ELI SEN S +V++A GS++TNKY+EGYPG RY Sbjct: 17 NASLEDIDPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRY 76 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG +Y+D+ E L +RA + F+ + NVQP SGS N V+ ALL+P D M LD Sbjct: 77 YGGCQYVDVVEELAIERAKKLFSAE----FANVQPNSGSQMNQAVFLALLQPGDTFMGLD 132 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG ++ +F + Y + + L+D D++ + A +PKLI+AG Sbjct: 133 LNSGGHLTHG-----SPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAGG 187 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 +AY+R++D+ R R+I D+ A L+ DMAHI+GLVA G PSP +A V TTTTHKSLRGP Sbjct: 188 TAYSRIWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRGP 247 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG MI D KIN+AVFPGLQGGP H I G AVA +A E Sbjct: 248 RGGMILTNDA-------------DIAKKINSAVFPGLQGGPLMHVIAGKAVAFAEALKLE 294 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y + V+ N+ AE L S G DIVSGGTDNHL+LV+L+ K G R E L +I Sbjct: 295 FKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAALGRANIT 354 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NKN +P D V G+R+GTPA T+RGF +F ++ Sbjct: 355 CNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFGVAEFKEI 393
>Q8YGG7:GLYA_BRUME Serine hydroxymethyltransferase - Brucella melitensis| Length = 438 Score = 337 bits (865), Expect = 8e-92 Identities = 187/399 (46%), Positives = 245/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 NA LE++DPEI I E RQ +ELI SEN S +V++A GS++TNKY+EGYPG RY Sbjct: 17 NASLEDIDPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRY 76 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG +Y+D+ E L +RA + F + NVQP SGS N V+ ALL+P D M LD Sbjct: 77 YGGCQYVDVVEELAIERAKKLFGAE----FANVQPNSGSQMNQAVFLALLQPGDTFMGLD 132 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG ++ +F + Y + + L+D D++ + A +PKLI+AG Sbjct: 133 LNSGGHLTHG-----SPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAGG 187 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 +AY+R++D+ R R+I D+ A L+ DMAHI+GLVA G PSP +A V TTTTHKSLRGP Sbjct: 188 TAYSRIWDWKRFREIADEVGACLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRGP 247 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG MI D KIN+AVFPGLQGGP H I G AVA +A E Sbjct: 248 RGGMILTNDA-------------DIAKKINSAVFPGLQGGPLMHVIAGKAVAFAEALKPE 294 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y + V+ N+ AE L S G DIVSGGTDNHL+LV+L+ K G R E L +I Sbjct: 295 FKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAALGRANIT 354 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NKN +P D V G+R+GTPA T+RGF +F ++ Sbjct: 355 CNKNGIPFDPEKPFVASGVRLGTPAGTTRGFGVAEFKEI 393
>Q57DY5:GLYA_BRUAB Serine hydroxymethyltransferase - Brucella abortus| Length = 438 Score = 337 bits (865), Expect = 8e-92 Identities = 187/399 (46%), Positives = 245/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 NA LE++DPEI I E RQ +ELI SEN S +V++A GS++TNKY+EGYPG RY Sbjct: 17 NASLEDIDPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRY 76 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG +Y+D+ E L +RA + F + NVQP SGS N V+ ALL+P D M LD Sbjct: 77 YGGCQYVDVVEELAIERAKKLFGAE----FANVQPNSGSQMNQAVFLALLQPGDTFMGLD 132 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG ++ +F + Y + + L+D D++ + A +PKLI+AG Sbjct: 133 LNSGGHLTHG-----SPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAGG 187 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 +AY+R++D+ R R+I D+ A L+ DMAHI+GLVA G PSP +A V TTTTHKSLRGP Sbjct: 188 TAYSRIWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRGP 247 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG MI D KIN+AVFPGLQGGP H I G AVA +A E Sbjct: 248 RGGMILTNDA-------------DIAKKINSAVFPGLQGGPLMHVIAGKAVAFAEALKPE 294 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y + V+ N+ AE L S G DIVSGGTDNHL+LV+L+ K G R E L +I Sbjct: 295 FKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAALGRANIT 354 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NKN +P D V G+R+GTPA T+RGF +F ++ Sbjct: 355 CNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFGVAEFKEI 393
>Q2YN95:GLYA_BRUA2 Serine hydroxymethyltransferase - Brucella abortus (strain 2308)| Length = 438 Score = 337 bits (865), Expect = 8e-92 Identities = 187/399 (46%), Positives = 245/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 NA LE++DPEI I E RQ +ELI SEN S +V++A GS++TNKY+EGYPG RY Sbjct: 17 NASLEDIDPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRY 76 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG +Y+D+ E L +RA + F + NVQP SGS N V+ ALL+P D M LD Sbjct: 77 YGGCQYVDVVEELAIERAKKLFGAE----FANVQPNSGSQMNQAVFLALLQPGDTFMGLD 132 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG ++ +F + Y + + L+D D++ + A +PKLI+AG Sbjct: 133 LNSGGHLTHG-----SPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAGG 187 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 +AY+R++D+ R R+I D+ A L+ DMAHI+GLVA G PSP +A V TTTTHKSLRGP Sbjct: 188 TAYSRIWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRGP 247 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG MI D KIN+AVFPGLQGGP H I G AVA +A E Sbjct: 248 RGGMILTNDA-------------DIAKKINSAVFPGLQGGPLMHVIAGKAVAFAEALKPE 294 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y + V+ N+ AE L S G DIVSGGTDNHL+LV+L+ K G R E L +I Sbjct: 295 FKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAALGRANIT 354 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NKN +P D V G+R+GTPA T+RGF +F ++ Sbjct: 355 CNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFGVAEFKEI 393
>Q87AS2:GLYA_XYLFT Serine hydroxymethyltransferase - Xylella fastidiosa (strain| Temecula1 / ATCC 700964) Length = 417 Score = 337 bits (864), Expect = 1e-91 Identities = 188/402 (46%), Positives = 252/402 (62%), Gaps = 1/402 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 +A L+ DPE+A I E RQ +ELI SEN+ S VMQ GS +TNKY+EGY G RY Sbjct: 5 DARLDMYDPELAKAIAAEVRRQEDHVELIASENYCSTLVMQVQGSQLTNKYAEGYSGKRY 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG EY+D+AE L +RA + F D NVQP SGS AN VY ALL+P D I+ + Sbjct: 65 YGGCEYVDIAEQLAIERAKKLFGADY----ANVQPHSGSQANQAVYFALLQPGDTILGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG ++ F + Y ++ + GLIDY+ +E A+ RPK++VAG Sbjct: 121 LAHGGHLTHG-----ANVNVSGKLFNAVQYGVN-AQGLIDYEAVESLALEHRPKMVVAGF 174 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY++ D+ R R I D+ A LL DMAH++GLVAAGV PSP +A VVT+TTHK+LRGP Sbjct: 175 SAYSQKIDWARFRAIADQVGAYLLVDMAHVAGLVAAGVYPSPLPHAHVVTSTTHKTLRGP 234 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I + + + K K+ + VFPG+QGGP H I AVA K+A Sbjct: 235 RGGIIVAQAPQEALVK-----------KLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPA 283 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ YQ+QV+ N+ A +L +GY IVSGGT+NHL+LV++ + + G E L VHI Sbjct: 284 FKVYQQQVVKNAKAMAGTLMLRGYKIVSGGTENHLMLVDMIGRDVSGKDAEGALGQVHIT 343 Query: 1299 ANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NKN VP D S V G+R+GTPA+T+RG+ E+D +A + Sbjct: 344 VNKNAVPDDPRSPFVTSGLRLGTPAVTTRGYQEQDCVDLAHW 385
>Q983B6:GLYA1_RHILO Serine hydroxymethyltransferase 1 - Rhizobium loti (Mesorhizobium| loti) Length = 437 Score = 337 bits (864), Expect = 1e-91 Identities = 187/398 (46%), Positives = 245/398 (61%), Gaps = 1/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE+ DPEI I E RQ +ELI SEN S +V++A GS+MTNKY+EGYPG RYYGG Sbjct: 19 LEDADPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSIMTNKYAEGYPGKRYYGG 78 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 +++D+AE L +RA + F + NVQP SGS N V+ ALL+P D M LDL Sbjct: 79 CQFVDVAEELAIERAKKLFGCN----FANVQPNSGSQMNQAVFLALLQPGDTFMGLDLNS 134 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F+ + Y + + L+D D +EK+A +PKLI+AG +AY Sbjct: 135 GGHLTHG-----SPVNMSGKWFKVVSYGVRKEDHLLDMDAIEKTAHETKPKLILAGGTAY 189 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R++D+ R R+I D A L+ DMAHI+GLVA GV PSP +A VVTTTTHKSLRGPRG Sbjct: 190 SRIWDWKRFREIADAVGAYLMVDMAHIAGLVAGGVHPSPLPHAHVVTTTTHKSLRGPRGG 249 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI D K+N+AVFPGLQGGP H I AVA +A ++ Sbjct: 250 MILCN-------------DEDIAKKMNSAVFPGLQGGPLMHVIAAKAVAFGEALKPSFKV 296 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y E V +N+ A SL G DIVSGGTDNHL+LV+L+ K G R E L +I NK Sbjct: 297 YAESVAANAKALASSLKETGLDIVSGGTDNHLMLVDLRPKNATGKRAEAALGRANITCNK 356 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 N +P D V G+R+GTPA T+RGF + +F ++ + Sbjct: 357 NGIPFDPEKPFVTSGVRLGTPAGTTRGFGQAEFREIGK 394
>P24060:GLYA_BRAJA Serine hydroxymethyltransferase - Bradyrhizobium japonicum| Length = 432 Score = 337 bits (863), Expect = 1e-91 Identities = 191/412 (46%), Positives = 247/412 (59%), Gaps = 1/412 (0%) Frame = +3 Query: 180 TEERSAVTWPKQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVM 359 T ++A A L++ DPEIA I+ E RQ +ELI SEN S +V++A GSVM Sbjct: 2 TSAKTASAPDSFFTASLDQADPEIAAAIKGELGRQRHEVELIASENIVSRAVLEAQGSVM 61 Query: 360 TNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYT 539 TNKY+EGYPGARYYGG E++D+AE L RA + F NVQP SGS N V+ Sbjct: 62 TNKYAEGYPGARYYGGCEWVDVAENLAIDRAKKLFGAG----FANVQPNSGSQMNQAVFL 117 Query: 540 ALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKS 719 ALL+P D M LDL GGHL+HG ++ +F+ Y + +ID D ++K Sbjct: 118 ALLQPGDTFMGLDLAAGGHLTHG-----SPVNMSGKWFKAAHYTVRREDQIIDMDAVQKQ 172 Query: 720 AVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYAD 899 A +PKLIVAG SAY+R +D+ R R+I D A LL DMAH +GLVA GV SP YA Sbjct: 173 AEEIKPKLIVAGGSAYSRAWDFKRFREIADSVGAYLLVDMAHFAGLVAGGVHASPVPYAH 232 Query: 900 VVTTTTHKSLRGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTIT 1079 V TTTTHKSLRGPRG +I K+N+A+FPGLQGGP H I Sbjct: 233 VTTTTTHKSLRGPRGGLILSNDET-------------LAKKLNSAIFPGLQGGPLMHVIA 279 Query: 1080 GLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDG 1259 AVA +A +++ Y + V+ N+ AE++ S G+DIVSGGTDNHL+LV+L+ KG+ G Sbjct: 280 AKAVAFGEALRPDFKVYAKNVVENAKALAEAMKSHGFDIVSGGTDNHLMLVDLRPKGLKG 339 Query: 1260 SRVEKVLENVHIAANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 + EK L I NKN +P D V G+R+GTPA T+RGF +F +V Sbjct: 340 NVSEKALVRAAITCNKNGIPFDPEKPFVTSGLRLGTPAATTRGFGVAEFQQV 391
>Q7VUW7:GLYA_BORPE Serine hydroxymethyltransferase - Bordetella pertussis| Length = 415 Score = 337 bits (863), Expect = 1e-91 Identities = 190/457 (41%), Positives = 264/457 (57%), Gaps = 1/457 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N L++VDP++ I+ E RQ + +ELI SEN+ S +VMQA G+ +TNKY+EGYPG RY Sbjct: 5 NLTLDQVDPDVWAAIQKEDVRQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRY 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG EY+D+ E L R + F + NVQP SGS AN VY A+LKP D ++ + Sbjct: 65 YGGCEYVDVVEQLAIDRLKQIFGAE----AANVQPNSGSQANQGVYMAVLKPGDTVLGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG ++A + +PY LD ++DY Q+E+ +PKLIVAGA Sbjct: 121 LAEGGHLTHG-----ASVNASGKLYNFVPYGLDADE-VLDYAQVERLTKEHKPKLIVAGA 174 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAYA D+ RM +I A+ + D+AH +GLVA G P+P +AD VT+TTHKSLRGP Sbjct: 175 SAYALHIDFERMARIAHDNGALFMVDIAHYAGLVAGGAYPNPVPHADFVTSTTHKSLRGP 234 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I +K +FE +N+A+FPG+QGGP H I AVA K+A + E Sbjct: 235 RGGVIM--------------MKAEFEKAVNSAIFPGIQGGPLMHVIAAKAVAFKEALSPE 280 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y +QV+ N+ A++L +G IVSG T++H++LV+L+ KGI G E VL HI Sbjct: 281 FQDYAQQVVKNAKVLADTLVKRGLRIVSGRTESHVMLVDLRPKGITGKEAEAVLGQAHIT 340 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGT 1475 NKN +P D V GIR+GTPA+T+RGF E + A Sbjct: 341 VNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTA-------------------- 380 Query: 1476 KLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 + +A + + +A IA +R V E + P G Sbjct: 381 ---NLIADVLDNPRDEANIAAVRARVNELTARLPVYG 414
>Q7WFD2:GLYA2_BORBR Serine hydroxymethyltransferase 2 - Bordetella bronchiseptica| (Alcaligenes bronchisepticus) Length = 415 Score = 337 bits (863), Expect = 1e-91 Identities = 190/457 (41%), Positives = 264/457 (57%), Gaps = 1/457 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N L++VDP++ I+ E RQ + +ELI SEN+ S +VMQA G+ +TNKY+EGYPG RY Sbjct: 5 NLTLDQVDPDVWAAIQKEDVRQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRY 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG EY+D+ E L R + F + NVQP SGS AN VY A+LKP D ++ + Sbjct: 65 YGGCEYVDVVEQLAIDRLKQIFGAE----AANVQPNSGSQANQGVYMAVLKPGDTVLGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG ++A + +PY LD ++DY Q+E+ +PKLIVAGA Sbjct: 121 LAEGGHLTHG-----ASVNASGKLYNFVPYGLDADE-VLDYAQVERLTKEHKPKLIVAGA 174 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAYA D+ RM +I A+ + D+AH +GLVA G P+P +AD VT+TTHKSLRGP Sbjct: 175 SAYALHIDFERMARIAHDNGALFMVDIAHYAGLVAGGAYPNPVPHADFVTSTTHKSLRGP 234 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I +K +FE +N+A+FPG+QGGP H I AVA K+A + E Sbjct: 235 RGGVIM--------------MKAEFEKAVNSAIFPGIQGGPLMHVIAAKAVAFKEALSPE 280 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y +QV+ N+ A++L +G IVSG T++H++LV+L+ KGI G E VL HI Sbjct: 281 FQDYAQQVVKNAKVLADTLVKRGLRIVSGRTESHVMLVDLRPKGITGKEAEAVLGQAHIT 340 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGT 1475 NKN +P D V GIR+GTPA+T+RGF E + A Sbjct: 341 VNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTA-------------------- 380 Query: 1476 KLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 + +A + + +A IA +R V E + P G Sbjct: 381 ---NLIADVLDNPRDEANIAAVRARVNELTARLPVYG 414
>Q8DH33:GLYA_SYNEL Serine hydroxymethyltransferase - Synechococcus elongatus| (Thermosynechococcus elongatus) Length = 425 Score = 336 bits (862), Expect = 2e-91 Identities = 184/398 (46%), Positives = 246/398 (61%), Gaps = 1/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L + DP +A++++ E RQ + LELI SENFTS +VM A G+V+TNKY+EG PG RYYGG Sbjct: 7 LVQTDPLVAEMVQREVQRQQQHLELIASENFTSPAVMAAQGTVLTNKYAEGLPGKRYYGG 66 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L RA E F NVQP SG+ ANF V+ ALL P D IM +DL H Sbjct: 67 CEFVDEVEQLAIDRAKELFGAAH----ANVQPHSGAQANFAVFLALLNPGDTIMGMDLSH 122 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y + T +D DQ+ A RPKLI+ G SAY Sbjct: 123 GGHLTHG-----SPVNVSGKWFNVVHYGVHPETERLDMDQVRDLARQHRPKLIICGYSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ + R+I D+ A L+AD+AHI+GLVA+G P+P DVVTTTTHK+LRGPRG Sbjct: 178 PRVIPFAEFRQIADEVGAYLMADIAHIAGLVASGYHPNPVPLCDVVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R D K++ AVFPG QGGP H I AVA +A E++A Sbjct: 238 LILTR-------------DEDLGKKLDKAVFPGTQGGPLEHVIAAKAVAFGEALKPEFKA 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV+ N+ A L ++ +VSGGTDNHL+L++L+ + G ++++ +HI NK Sbjct: 285 YCGQVIRNAQALAAGLQARQLRLVSGGTDNHLMLIDLRSVNLTGKEADRLMGEIHITTNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 NT+P D S V G+R+GTPALT+RGF E +FA+VAE Sbjct: 345 NTIPFDPASPFVTSGLRLGTPALTTRGFTEVEFAEVAE 382
>Q601P7:GLYA_MYCH2 Serine hydroxymethyltransferase - Mycoplasma hyopneumoniae (strain| 232) Length = 418 Score = 336 bits (862), Expect = 2e-91 Identities = 186/398 (46%), Positives = 255/398 (64%), Gaps = 2/398 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D +I+++I LE RQ +ELI SEN+ S V+ A G+ ++NKY EGYPG RYYGG +I Sbjct: 9 DQQISELINLESKRQNSQIELIASENYASEDVILANGTSLSNKYGEGYPGKRYYGGCTFI 68 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D E + +R + F ++ NVQP SGS AN V+ ALLKP D+I+ LDL GGHL Sbjct: 69 DQIEKIAIERVKKLFKIEY----ANVQPYSGSSANAAVFAALLKPGDKILGLDLNAGGHL 124 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 SHGY KI+ +F+ + Y LDE+ L+DYD +EK A+ +P LI+ G SAY+R Sbjct: 125 SHGY-----KINFSGMFYSGISYFLDENE-LLDYDAIEKIALKTKPNLIICGYSAYSRKI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R R+I DK A LLAD+AHI+GL+AAG PSP YA ++T+TT K+LRGPRG +I Sbjct: 179 DFARFRQIADKVNAFLLADIAHIAGLIAAGQHPSPVGYAHIITSTTQKTLRGPRGGLILT 238 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 KEI KI+ VFPG+QGGP HTI AVA K+A ++ Y Q Sbjct: 239 NS--KEI-----------AAKIDKVVFPGIQGGPFFHTIAAKAVAFKEALEPWFKEYCAQ 285 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVN-LKKKGIDGSRVEKVLENVHIAANKNTV 1316 ++ N++ FA KG IVS GT+NHL ++ L ++G + + +LE+V+I NKNT+ Sbjct: 286 IVKNASHFASEFIKKGIRIVSQGTENHLFTIDVLSSYNLNGKQAQILLESVNIITNKNTI 345 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 P D +S V G+R+GTPA+TSRGF E++F+++AE D Sbjct: 346 PNDTLSPFVTSGLRLGTPAMTSRGFKEQEFSQMAEIID 383
>Q2SYS4:GLYA1_BURTA Serine hydroxymethyltransferase 1 - Burkholderia thailandensis| (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) Length = 415 Score = 336 bits (862), Expect = 2e-91 Identities = 183/388 (47%), Positives = 245/388 (63%), Gaps = 1/388 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + VDPEI I+ E RQ + +ELI SEN+TS +VM A GS +TNKY+EGYPG RYYGG Sbjct: 9 IANVDPEIWQAIQQENVRQEEHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L R F + NVQP SGS AN V+ A+LKP D IM + L H Sbjct: 69 CEYVDIVEQLAIDRVKALFGSE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y L+E+ IDY+ +K A +PKLIVAGASA+ Sbjct: 125 GGHLTHG-----SPVNMSGKWFNVVSYGLNENED-IDYEAADKLAHEHKPKLIVAGASAF 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 A D+ R+ KI A L+ DMAH +GL+AAGV P+P +AD VTTTTHKSLRGPRG Sbjct: 179 ALKIDFERLAKIAKAVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +K ++E +IN+A+FPG+QGGP H I AVA K+A + E++ Sbjct: 239 VIL--------------MKAEYEKQINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKE 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ++V+ N+ AE+L +G IVSG T++H++LV+L+ K I G E L N HI NK Sbjct: 285 YQQKVIENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGNAHITVNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGF 1388 N +P D V G+R+G+PA+T+RGF Sbjct: 345 NAIPNDPEKPFVTSGVRLGSPAMTTRGF 372
>Q63RB4:GLYA1_BURPS Serine hydroxymethyltransferase 1 - Burkholderia pseudomallei| (Pseudomonas pseudomallei) Length = 415 Score = 336 bits (862), Expect = 2e-91 Identities = 192/451 (42%), Positives = 263/451 (58%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + VDPEI I+ E RQ + +ELI SEN+TS +VM A GS +TNKY+EGYPG RYYGG Sbjct: 9 IANVDPEIWQAIQQENVRQEEHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L R F + NVQP SGS AN V+ A+LKP D IM + L H Sbjct: 69 CEYVDIVEQLAIDRVKALFGAE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y L+E+ IDY+ E+ A +PKLIVAGASA+ Sbjct: 125 GGHLTHG-----SPVNMSGKWFNVVSYGLNEAED-IDYEAAEQLAHEHKPKLIVAGASAF 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 A D+ R+ KI A L+ DMAH +GL+AAGV P+P +AD VTTTTHKSLRGPRG Sbjct: 179 ALKIDFERLAKIAKAVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +K ++E +IN+A+FPG+QGGP H I AVA K+A + E++ Sbjct: 239 VIL--------------MKAEYEKQINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKE 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ++V+ N+ A++L +G IVSG T++H++LV+L+ K I G E L N HI NK Sbjct: 285 YQQKVVENARVLAQTLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGNAHITVNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D V G+R+G+PA+T+RGF ++ V Sbjct: 345 NAIPNDPEKPFVTSGVRLGSPAMTTRGFGPQEAELVG----------------------- 381 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 + +A + A I ++R V E K+FP Sbjct: 382 NLIADVLEHPEDAATIERVRAQVAELTKRFP 412
>Q3JP81:GLYA1_BURP1 Serine hydroxymethyltransferase 1 - Burkholderia pseudomallei (strain| 1710b) Length = 415 Score = 336 bits (862), Expect = 2e-91 Identities = 192/451 (42%), Positives = 263/451 (58%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + VDPEI I+ E RQ + +ELI SEN+TS +VM A GS +TNKY+EGYPG RYYGG Sbjct: 9 IANVDPEIWQAIQQENVRQEEHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L R F + NVQP SGS AN V+ A+LKP D IM + L H Sbjct: 69 CEYVDIVEQLAIDRVKALFGAE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y L+E+ IDY+ E+ A +PKLIVAGASA+ Sbjct: 125 GGHLTHG-----SPVNMSGKWFNVVSYGLNEAED-IDYEAAEQLAHEHKPKLIVAGASAF 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 A D+ R+ KI A L+ DMAH +GL+AAGV P+P +AD VTTTTHKSLRGPRG Sbjct: 179 ALKIDFERLAKIAKAVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +K ++E +IN+A+FPG+QGGP H I AVA K+A + E++ Sbjct: 239 VIL--------------MKAEYEKQINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKE 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ++V+ N+ A++L +G IVSG T++H++LV+L+ K I G E L N HI NK Sbjct: 285 YQQKVVENARVLAQTLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGNAHITVNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D V G+R+G+PA+T+RGF ++ V Sbjct: 345 NAIPNDPEKPFVTSGVRLGSPAMTTRGFGPQEAELVG----------------------- 381 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 + +A + A I ++R V E K+FP Sbjct: 382 NLIADVLEHPEDAATIERVRAQVAELTKRFP 412
>Q62I16:GLYA1_BURMA Serine hydroxymethyltransferase 1 - Burkholderia mallei (Pseudomonas| mallei) Length = 415 Score = 336 bits (862), Expect = 2e-91 Identities = 192/451 (42%), Positives = 263/451 (58%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + VDPEI I+ E RQ + +ELI SEN+TS +VM A GS +TNKY+EGYPG RYYGG Sbjct: 9 IANVDPEIWQAIQQENVRQEEHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L R F + NVQP SGS AN V+ A+LKP D IM + L H Sbjct: 69 CEYVDIVEQLAIDRVKALFGAE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y L+E+ IDY+ E+ A +PKLIVAGASA+ Sbjct: 125 GGHLTHG-----SPVNMSGKWFNVVSYGLNEAED-IDYEAAEQLAHEHKPKLIVAGASAF 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 A D+ R+ KI A L+ DMAH +GL+AAGV P+P +AD VTTTTHKSLRGPRG Sbjct: 179 ALKIDFERLAKIAKAVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +K ++E +IN+A+FPG+QGGP H I AVA K+A + E++ Sbjct: 239 VIL--------------MKAEYEKQINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKE 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ++V+ N+ A++L +G IVSG T++H++LV+L+ K I G E L N HI NK Sbjct: 285 YQQKVVENARVLAQTLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGNAHITVNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D V G+R+G+PA+T+RGF ++ V Sbjct: 345 NAIPNDPEKPFVTSGVRLGSPAMTTRGFGPQEAELVG----------------------- 381 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 + +A + A I ++R V E K+FP Sbjct: 382 NLIADVLEHPEDAATIERVRAQVAELTKRFP 412
>Q5LPA8:GLYA_SILPO Serine hydroxymethyltransferase - Silicibacter pomeroyi| Length = 431 Score = 336 bits (861), Expect = 2e-91 Identities = 188/399 (47%), Positives = 242/399 (60%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L E DPE+ I E RQ +ELI SEN S +VMQA GSVMTNKY+EGYPG RYYGG Sbjct: 15 LSERDPELFGAITSELGRQRDEIELIASENIVSAAVMQAQGSVMTNKYAEGYPGRRYYGG 74 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 +Y+D+AE L +RA + F NVQP SGS AN V+ AL+KP D I+ + L Sbjct: 75 CQYVDIAENLAIERAKQLFGCG----FANVQPNSGSQANQGVFQALIKPGDTILGMSLDA 130 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG + +F + Y + + L+DYDQ+E A RPKLI+AG SA Sbjct: 131 GGHLTHGAAPNQS-----GKWFNAVQYGVRQQDNLLDYDQVEALAKEHRPKLIIAGGSAI 185 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ RMR+I D A L DMAH +GLVAAG PSPF +A V TTTTHK+LRGPRG Sbjct: 186 PRQIDFARMREIADMVGAYLHVDMAHFAGLVAAGEHPSPFPHAHVATTTTHKTLRGPRGG 245 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI D K+N+A+FPG+QGGP H I AVA +A E++ Sbjct: 246 MILTN-------------DEDIAKKVNSAIFPGIQGGPLMHVIAAKAVAFGEALRPEFKT 292 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +QV++N+ ++ L G D V+ GTD H+VLV+L+ KG+ G+ EK L HI NK Sbjct: 293 YIQQVIANAQALSDQLIKGGLDTVTHGTDTHVVLVDLRPKGVKGNATEKALGRAHITCNK 352 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 N VP D V GIR+G+PA T+RGF E +F ++A++ Sbjct: 353 NGVPFDPEKPTVTSGIRLGSPAGTTRGFAETEFRQIADW 391
>Q92GH7:GLYA_RICCN Serine hydroxymethyltransferase - Rickettsia conorii| Length = 420 Score = 336 bits (861), Expect = 2e-91 Identities = 195/457 (42%), Positives = 266/457 (58%), Gaps = 1/457 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N L E D EI +II+ EK RQ +ELI SENF S +V++A G+++TNKY+EGYP R+ Sbjct: 5 NNNLHETDKEINEIIKHEKLRQSSVIELIASENFVSPAVLEAQGALLTNKYAEGYPSKRF 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 Y G E +D AE L +R + FN NVQP SGS AN VY ALL+P D ++ + Sbjct: 65 YNGCEEVDKAENLAIERVKKLFNCKY----ANVQPHSGSQANQAVYLALLQPGDTVLGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG + +F + Y +++ T LIDYD++E+ A L +PKL++AG Sbjct: 121 LDSGGHLTHGAAPNMS-----GKWFNAVSYSVNKETYLIDYDEIERLADLHKPKLLIAGF 175 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY R D+ + R+I DK A +AD+AHI+GLVA G SP YA VT+TTHK+LRGP Sbjct: 176 SAYPRNIDFAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIPYAHAVTSTTHKTLRGP 235 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I KIN+A+FPGLQGGP H I AVA + E Sbjct: 236 RGGLILSNDEA-------------IGHKINSALFPGLQGGPLMHIIAAKAVAFLENLQPE 282 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 Y++Y +QV+SN+ A SL +GYDI++GGTDNH+VLV+L+K GI G L+ I Sbjct: 283 YKSYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKLAANSLDRAGIT 342 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGT 1475 NKN +P D S + GIR+GTPA T+RGF E+DF V G Sbjct: 343 CNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLV-------------------GH 383 Query: 1476 KLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 + D + L+++ + A K+ ++V + + FP G Sbjct: 384 MVADILDGLKNNEDNSALEQKVLNEVTKLIELFPFYG 420
>Q4A8E1:GLYA_MYCH7 Serine hydroxymethyltransferase - Mycoplasma hyopneumoniae (strain| 7448) Length = 418 Score = 336 bits (861), Expect = 2e-91 Identities = 185/398 (46%), Positives = 255/398 (64%), Gaps = 2/398 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D +I+++I LE RQ +ELI SEN+ S V+ A G+ ++NKY EGYPG RYYGG +I Sbjct: 9 DQQISELINLESKRQNSQIELIASENYASEDVILANGTSLSNKYGEGYPGKRYYGGCTFI 68 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D E + +R + F ++ NVQP SGS AN V+ ALLKP D+I+ LDL GGHL Sbjct: 69 DQIEKIAIERVKKLFKIEY----ANVQPYSGSSANAAVFAALLKPGDKILGLDLNAGGHL 124 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 SHGY KI+ +F+ + Y LDE+ L+DY+ +EK A+ +P LI+ G SAY+R Sbjct: 125 SHGY-----KINFSGMFYSGISYFLDENE-LLDYEAIEKIALKTKPNLIICGYSAYSRKI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R R+I DK A LLAD+AHI+GL+AAG PSP YA ++T+TT K+LRGPRG +I Sbjct: 179 DFARFRQIADKVNAFLLADIAHIAGLIAAGQHPSPVGYAHIITSTTQKTLRGPRGGLIL- 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 KE+ KI+ VFPG+QGGP HTI AVA K+A ++ Y Q Sbjct: 238 --------TSSKEI----AAKIDKVVFPGIQGGPFFHTIAAKAVAFKEALEPWFKEYCAQ 285 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVN-LKKKGIDGSRVEKVLENVHIAANKNTV 1316 ++ N+A FA KG IVS GT+NHL ++ L ++G + + +LE+V+I NKNT+ Sbjct: 286 IVKNAAHFASEFIKKGIRIVSQGTENHLFTIDVLSSYNLNGKQAQILLESVNIITNKNTI 345 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 P D +S V G+R+GTPA+TSRGF E++F+++AE D Sbjct: 346 PNDTLSPFVTSGLRLGTPAMTSRGFKEQEFSQMAEIID 383
>P24531:GLYA_CAMJE Serine hydroxymethyltransferase - Campylobacter jejuni| Length = 414 Score = 336 bits (861), Expect = 2e-91 Identities = 187/399 (46%), Positives = 253/399 (63%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE D EI D+ E RQ +GLE+I SENFT VM+ +GS++TNKY+EGYPG RYYGG Sbjct: 3 LEMFDKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRYYGG 62 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D ETL +R + FN NVQP SGS AN VY AL+ P D+I+ +DL H Sbjct: 63 CEFVDEIETLAIERCKKLFNCK----FANVQPNSGSQANQGVYAALINPGDKILGMDLSH 118 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K+S+ +E+ Y + E G IDY+++ + A +PKLIV GASAY Sbjct: 119 GGHLTHG-----AKVSSSGKMYESCFYGV-ELDGRIDYEKVREIAKKEKPKLIVCGASAY 172 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 AR+ D+ + R+I D+ A L AD+AHI+GLV AG PSPF YA VV++TTHK+LRGPRG Sbjct: 173 ARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAHVVSSTTHKTLRGPRGG 232 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +E+ K KIN+A+FPG+QGGP H I AV K + E++ Sbjct: 233 IIMTND--EELAK-----------KINSAIFPGIQGGPLMHVIAAKAVGFKFNLSDEWKV 279 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +QV +N+ A L + + +VS GTDNHLVL++ + G + L N I ANK Sbjct: 280 YAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGITANK 339 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NTVPG++ S + G+R+GTPALT+RGF E++ V+ + Sbjct: 340 NTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNY 378
>Q3MBD8:GLYA_ANAVT Serine hydroxymethyltransferase - Anabaena variabilis (strain ATCC| 29413 / PCC 7937) Length = 427 Score = 336 bits (861), Expect = 2e-91 Identities = 183/396 (46%), Positives = 247/396 (62%), Gaps = 1/396 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L DP IA +I E RQ LELI SENFTS +V+ A GSV+TNKY+EG PG RYYGG Sbjct: 9 LTNSDPAIAGLINQELQRQRDHLELIASENFTSAAVLAAQGSVLTNKYAEGLPGKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E+ID E + RA + F NVQP SG+ ANF V+ LL P D+IM +DL H Sbjct: 69 CEFIDKIEQIAIDRAKQLFGAAH----ANVQPHSGAQANFAVFLTLLAPGDKIMGMDLSH 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F+ Y + + T +DYDQ+ + A+ RPKL++ G SAY Sbjct: 125 GGHLTHG-----SPVNVSGKWFQVCHYGVSQQTEQLDYDQIRELALRERPKLLICGYSAY 179 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ + R I D+ A LLAD+AHI+GLVA+G+ P P Y VVTTTTHK+LRGPRG Sbjct: 180 PRIIDFEKFRSIADEVGAYLLADIAHIAGLVASGLHPDPIPYCHVVTTTTHKTLRGPRGG 239 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I G E+ K K++ +VFPG QGGP H I G AVA +A E++ Sbjct: 240 LIL--TGDAELGK-----------KLDKSVFPGSQGGPLEHVIAGKAVAFGEALKPEFQG 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV+ N+ A L ++G +VS GTDNHL+LV+L+ + G R ++++ V+I ANK Sbjct: 287 YSAQVIENARALANQLQNRGLKLVSDGTDNHLMLVDLRSVNMTGKRADQLVSEVNITANK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NTVP D S V G+R+G+PA+T+RG E +F ++ Sbjct: 347 NTVPFDPQSPFVTSGLRLGSPAMTTRGMGEAEFTEI 382
>Q6CZV5:GLYA2_ERWCT Serine hydroxymethyltransferase 2 - Erwinia carotovora subsp.| atroseptica (Pectobacterium atrosepticum) Length = 423 Score = 336 bits (861), Expect = 2e-91 Identities = 186/388 (47%), Positives = 243/388 (62%), Gaps = 1/388 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L E DPE+AD I E+ RQ +ELI SEN+ S VM SV TNKY+EGY G RYY G Sbjct: 8 LTEFDPELADAILHEEDRQETHVELIASENYASPLVMAIQNSVFTNKYAEGYLGKRYYSG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+AE L +RA F+ D NVQP +G+ AN V+ AL P D +M ++L Sbjct: 68 CEYVDVAERLAIERAKVLFDCDY----ANVQPHAGAQANAAVFLALTNPGDTVMGMNLAQ 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ ++ +PY LD TGLIDYD++E+ A+ RPK+++ G SAY Sbjct: 124 GGHLTHGNPSNFS-----GRHYKIVPYGLDSETGLIDYDEMERIALETRPKMLIGGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R D+ RMR I DK A+ DMAH++GLVAAG P+P A VVT+TTHK+LRGPRG Sbjct: 179 SRHKDWARMRTIADKVGAIFWVDMAHVAGLVAAGEYPNPLPQAHVVTSTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I KG E DF K+NAAVFPG+QGGP H I AVA K+A E+ Sbjct: 239 II-LAKGQSE----------DFYKKLNAAVFPGIQGGPLMHVIAAKAVAFKEALRPEFTV 287 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ QV++N+ A + +GY IVS GTDNHL+L++L K G + L + +I NK Sbjct: 288 YQRQVVANARAMARIIQQRGYKIVSDGTDNHLLLIDLSAKPYTGKDADAALSDAYITTNK 347 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGF 1388 N+VP D S V G+R+GTPA+T+RGF Sbjct: 348 NSVPNDPRSPFVTSGLRIGTPAVTTRGF 375
>Q3IZN2:GLYA_RHOS4 Serine hydroxymethyltransferase - Rhodobacter sphaeroides (strain| ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) Length = 431 Score = 335 bits (859), Expect = 4e-91 Identities = 189/396 (47%), Positives = 244/396 (61%), Gaps = 1/396 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L DPE+ I E RQ +ELI SEN S +VM+A GSVMTNKY+EGY G RYYGG Sbjct: 15 LSSRDPELFASITGELGRQRDEIELIASENIVSRAVMEAQGSVMTNKYAEGYAGKRYYGG 74 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 +Y+D+AETL +RA + F VNVQP SGS AN V+ AL+KP D I+ ++L Sbjct: 75 CDYVDVAETLAIERAKQLFGCAY----VNVQPNSGSQANQGVFQALIKPGDTILGMELAS 130 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG + +F + Y + + LIDYDQ+ A +PKLI+AG SA Sbjct: 131 GGHLTHGAAPNQS-----GKWFNAIQYGVRQQDQLIDYDQVAALAREHKPKLIIAGGSAI 185 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ R R I D+ A+L+ DMAH +GLVA G PSPF +ADV TTTTHK+LRGPRG Sbjct: 186 PRQIDFARFRAIADEVGALLMVDMAHFAGLVAGGAHPSPFPHADVATTTTHKTLRGPRGG 245 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI +EI K K+N+A+FPG+QGGP H I AVA +A E++A Sbjct: 246 MILTNS--EEIAK-----------KVNSAIFPGIQGGPLMHVIAAKAVAFGEALRPEFKA 292 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV+ N+ A+ L G DIV+GGTD HL+LV+L+ KG+ G+ EK L HI NK Sbjct: 293 YAAQVVKNAQALADELMKGGLDIVTGGTDTHLMLVDLRPKGVKGNATEKALGRAHITCNK 352 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 N +P D V G+R+GTPA T+RGF E +F ++ Sbjct: 353 NGIPFDPEKPTVTSGVRLGTPAGTTRGFGEAEFREI 388
>Q7VFL1:GLYA_HELHP Serine hydroxymethyltransferase - Helicobacter hepaticus| Length = 416 Score = 335 bits (859), Expect = 4e-91 Identities = 180/398 (45%), Positives = 246/398 (61%), Gaps = 1/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++E D E+ ++IE E RQ + LE+I SENFT SVM+A+GS++TNKY+EGYP RYYGG Sbjct: 5 IKEQDFEVFELIEKELERQNEHLEMIASENFTFPSVMEAMGSILTNKYAEGYPFKRYYGG 64 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E + +RA + F + VNVQP SGS AN VY A+LKP+D+I+ +DL H Sbjct: 65 CEFVDKIEEIAIERAKKLFGAN----FVNVQPHSGSQANAAVYAAILKPYDKILGMDLSH 120 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG + T S F+ E G IDYD+L A + +P ++V G SAY Sbjct: 121 GGHLTHGAKVSTSGQLYQSFFYGV------ELNGRIDYDKLALQAQVVKPNVLVCGFSAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ R+R+I D A L+ D+AH++GLV AG P+PF + +VTTTTHK+LRGPRG Sbjct: 175 TRELDFKRLREIADSVGAYLMGDIAHVAGLVVAGEYPNPFPHCHIVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 I + KIN AVFPG+QGGP H I G AV K+ E++ Sbjct: 235 AILTNDE-------------ELYAKINKAVFPGIQGGPLMHIIAGKAVGFKENLKPEWKI 281 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +QV SN AE L + Y++VSGG+DNHL+L++ K G + L N I NK Sbjct: 282 YAKQVKSNIQALAEVLIKRNYELVSGGSDNHLILMSFLNKDFSGKDADLALGNAGITVNK 341 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 NT+PG++ S + GIR+G+PALT+RG E++F + E Sbjct: 342 NTIPGEIRSPFITSGIRIGSPALTARGMKEKEFEWIGE 379
>Q4AAB2:GLYA_MYCHJ Serine hydroxymethyltransferase - Mycoplasma hyopneumoniae (strain J| / ATCC 25934 / NCTC 10110) Length = 418 Score = 335 bits (858), Expect = 5e-91 Identities = 186/398 (46%), Positives = 254/398 (63%), Gaps = 2/398 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D +I+++I LE RQ +ELI SEN+ S V+ A G+ +NKY EGYPG RYYGG +I Sbjct: 9 DQQISELINLESKRQNSQIELIASENYASEDVILANGTSPSNKYGEGYPGKRYYGGCTFI 68 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D E + +R + F ++ NVQP SGS AN V+ ALLKP D+I+ LDL GGHL Sbjct: 69 DQIEKIAIERVKKLFKIEY----ANVQPYSGSSANAAVFAALLKPGDKILGLDLNAGGHL 124 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 SHGY KI+ +F+ + Y LDE+ L+DYD +EK A+ +P LI+ G SAY+R Sbjct: 125 SHGY-----KINFSGMFYSGISYFLDENE-LLDYDAIEKIALKTKPNLIICGYSAYSRKI 178 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R R+I DK A LLAD+AHI+GL+AAG PSP YA ++T+TT K+LRGPRG +I Sbjct: 179 DFARFRQIADKVNAFLLADIAHIAGLIAAGQHPSPVGYAHIITSTTQKTLRGPRGGLILT 238 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 KEI KI+ VFPG+QGGP HTI AVA K+A ++ Y Q Sbjct: 239 NS--KEI-----------AAKIDKVVFPGIQGGPFFHTIAAKAVAFKEALEPWFKEYCAQ 285 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVN-LKKKGIDGSRVEKVLENVHIAANKNTV 1316 ++ N++ FA KG IVS GT+NHL ++ L ++G + + +LE+V+I NKNT+ Sbjct: 286 IVKNASHFASEFIKKGIRIVSQGTENHLFTIDVLSSYNLNGKQAQILLESVNIITNKNTI 345 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 P D +S V G+R+GTPA+TSRGF E++F+++AE D Sbjct: 346 PNDTLSPFVTSGLRLGTPAMTSRGFKEQEFSQMAEIID 383
>Q2FLH5:GLYA_METHJ Serine hydroxymethyltransferase - Methanospirillum hungatei (strain| JF-1 / DSM 864) Length = 414 Score = 335 bits (858), Expect = 5e-91 Identities = 183/399 (45%), Positives = 244/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE DPEIA II+ E RQ GLELI SEN S +V++A GS+MTNKY+EGYPG RYYGG Sbjct: 4 LETTDPEIAAIIDKETNRQINGLELIASENVVSRAVLEASGSIMTNKYAEGYPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E+ DMAE L + R F + NVQP SGS AN VY +LKP D+I++++L Sbjct: 64 CEFHDMAENLARDRVCSLFGAEH----ANVQPHSGSQANMAVYFTVLKPSDKILSMNLSQ 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHLSHG ++ I +E+ Y +D T +DY + + A +PK+IV GASAY Sbjct: 120 GGHLSHG-----SPVNFSGIIYESHQYGVDLKTERMDYGTIAEMARTIKPKIIVCGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ +I ++ A +AD+AHI+GL A G+ PSP T+TTHK+LRGPRG Sbjct: 175 PREIDFKAFAEISEEVGAYCVADIAHIAGLCATGIHPSPVGLTTFTTSTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 I K +F I+ AVFPG+QGGP H I AV K+A+T+E++ Sbjct: 235 FILCDK--------------EFAAPIDKAVFPGMQGGPLMHIIAAKAVCFKEASTKEFKK 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y EQV+ N+ AE+L++ G +VSGGTDNHL L++L GI G E+ L N I NK Sbjct: 281 YSEQVVKNARTMAETLSANGVRLVSGGTDNHLCLLDLTNFGITGLEAEQALGNAGITVNK 340 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NT+P + S V G+R+GTPA+TSRG E + ++ E+ Sbjct: 341 NTIPNETKSPFVTSGLRVGTPAVTSRGMKESEMKQIGEW 379
>Q82JI0:GLYA_STRAW Serine hydroxymethyltransferase - Streptomyces avermitilis| Length = 420 Score = 334 bits (857), Expect = 7e-91 Identities = 188/407 (46%), Positives = 250/407 (61%), Gaps = 6/407 (1%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 LN PL E+DP++A ++ E RQ LE+I SENF ++VM+A GSV+TNKY+EGYPG R Sbjct: 4 LNTPLHELDPDVAAAVDAELNRQQSTLEMIASENFAPVAVMEAQGSVLTNKYAEGYPGRR 63 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 YYGG E++D+ E + R E F + NVQP SG+ AN ALLKP D IM L Sbjct: 64 YYGGCEHVDVVEQIAIDRVKELFGAEH----ANVQPHSGAQANAAAMFALLKPGDTIMGL 119 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 +L HGGHL+HG KI+ + + Y +DE+TG +D ++EK A RPKLIVAG Sbjct: 120 NLAHGGHLTHGM-----KINFSGKLYNVVAYHVDETTGQVDMAEVEKLAKESRPKLIVAG 174 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 SAY R D+ R+I D+ A L+ DMAH +GLVAAG+ P+P +A VVTTTTHK+L G Sbjct: 175 WSAYPRQLDFAAFRRIADEVGAYLMVDMAHFAGLVAAGLHPNPVPHAHVVTTTTHKTLGG 234 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG +I E+ K KIN+AVFPG QGGP H I AV+ K A + Sbjct: 235 PRGGVIL---STAELAK-----------KINSAVFPGQQGGPLEHVIAAKAVSFKVAASD 280 Query: 1116 EYRAYQEQVMSNSARFAESLT-----SKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVL 1280 +++ Q++ + + AE L + G D++SGGTD HLVLV+L+ +DG + E L Sbjct: 281 DFKERQQRTLDGARILAERLVRDDVKAVGVDVLSGGTDVHLVLVDLRDSELDGQQAEDRL 340 Query: 1281 ENVHIAANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 V I N+N +P D MV G+R+GTPAL +RGF DF +VA+ Sbjct: 341 HEVGITVNRNAIPNDPRPPMVTSGLRIGTPALATRGFQAADFTEVAD 387
>Q4UK96:GLYA_RICFE Serine hydroxymethyltransferase - Rickettsia felis (Rickettsia azadi)| Length = 421 Score = 334 bits (857), Expect = 7e-91 Identities = 190/399 (47%), Positives = 247/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N L E D EI +II+ EK RQ +ELI SENF S +V++A GS++TNKY+EGY G R+ Sbjct: 5 NNHLHETDKEIDEIIKHEKLRQNSVIELIASENFVSPAVLEAQGSILTNKYAEGYSGKRF 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 Y G E +D AE L +R + FN NVQ SGS AN VY ALL+P D I+ + Sbjct: 65 YNGCEEVDKAENLAIERVKKLFNCKY----ANVQSHSGSQANQAVYLALLQPGDTILGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG + +F + Y +++ T LIDYD++E+ A L +PKL++AG Sbjct: 121 LDSGGHLTHGAAPNMS-----GKWFNAVSYSVNKETYLIDYDEIERLADLHKPKLLIAGF 175 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY R D+ R R+I DK A +AD+AHI+GLVA G SP Y VT+TTHK+LRGP Sbjct: 176 SAYPRNIDFARFREIADKVGAYFMADIAHIAGLVATGEHQSPIPYTHAVTSTTHKTLRGP 235 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I +EI K KIN+A+FPGLQGGP H I AVA + E Sbjct: 236 RGGLIL--SNDEEIGK-----------KINSALFPGLQGGPLMHIIAAKAVAFLENLQPE 282 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 Y++Y +QV+SN+ A SL +GYDI++GGTDNH+VLV+L K GI G L+ I Sbjct: 283 YKSYIKQVISNAKALASSLQERGYDILTGGTDNHIVLVDLCKDGITGKLAANSLDRAGIT 342 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NKN +P D S + GIR+GTPA T+RGF E+DF V Sbjct: 343 CNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLV 381
>Q5HW65:GLYA_CAMJR Serine hydroxymethyltransferase - Campylobacter jejuni (strain| RM1221) Length = 414 Score = 334 bits (857), Expect = 7e-91 Identities = 186/399 (46%), Positives = 253/399 (63%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE D EI D+ E RQ +GLE+I SENFT VM+ +GS++TNKY+EGYPG RYYGG Sbjct: 3 LEMFDKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRYYGG 62 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D ETL +R + FN NVQP SGS AN VY AL+ P D+I+ +DL H Sbjct: 63 CEFVDEIETLAIERCKKLFNCK----FANVQPNSGSQANQGVYAALINPGDKILGMDLSH 118 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K+S+ +E+ Y + E G IDY+++ + A +PKLIV GASAY Sbjct: 119 GGHLTHG-----AKVSSSGKMYESCFYGV-ELDGRIDYEKVREIAKKEKPKLIVCGASAY 172 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 AR+ D+ + R+I D+ A L AD+AHI+GLV AG PSPF +A VV++TTHK+LRGPRG Sbjct: 173 ARVIDFAKFREIADEVGAYLFADIAHIAGLVVAGEHPSPFPHAHVVSSTTHKTLRGPRGG 232 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +E+ K KIN+A+FPG+QGGP H I AV K + E++ Sbjct: 233 IIMTND--EELAK-----------KINSAIFPGIQGGPLMHVIAAKAVGFKFNLSDEWKV 279 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +QV +N+ A L + + +VS GTDNHLVL++ + G + L N I ANK Sbjct: 280 YAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGITANK 339 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NTVPG++ S + G+R+GTPALT+RGF E++ V+ + Sbjct: 340 NTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNY 378
>P57376:GLYA_BUCAI Serine hydroxymethyltransferase - Buchnera aphidicola subsp.| Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) Length = 417 Score = 334 bits (857), Expect = 7e-91 Identities = 178/398 (44%), Positives = 249/398 (62%), Gaps = 1/398 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 DP++ IE EK RQ +ELI SEN+TS VM GS +TNKY+EGYPG RYYGG EY+ Sbjct: 12 DPKLWFAIEQEKKRQENHIELIASENYTSNYVMDVQGSQLTNKYAEGYPGKRYYGGCEYV 71 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D+ E L +RA + FN D NVQP SGS ANF VYTALL P D I+ + L HGGHL Sbjct: 72 DIIEELAIERAKKLFNADY----ANVQPHSGSQANFSVYTALLNPGDTILGMKLSHGGHL 127 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG ++ + + Y +DE+ G I+Y++L + ++PK+I+ G SAY+ + Sbjct: 128 THG-----SSVNFSGKMYNVISYGVDEN-GEINYEELLRLTKKYKPKMIIGGFSAYSGIC 181 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 ++ +MR I D A + DMAH++GLVAAG+ P+P YA VVT+TTHK+L GPRG +I Sbjct: 182 NWKKMRFIADNADAYFVVDMAHVAGLVAAGIYPNPINYAHVVTSTTHKTLAGPRGGLI-- 239 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 + K G ++ Y K+N +VFPG QGGP H I A+A K+A +++ YQ+Q Sbjct: 240 ------LAKNGDDILY---KKLNLSVFPGAQGGPLMHVIAAKAIAFKEALEPKFKTYQKQ 290 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 ++ NS E KGY I+SG T NHL L++L K I G + +L +I NKNT+P Sbjct: 291 IVKNSKVMVERFLEKGYKIISGHTFNHLFLIDLTNKKITGKDADIILSKANITVNKNTIP 350 Query: 1320 GDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS 1430 D+ S + GIR+GT A+T RGF E + ++++++ S Sbjct: 351 NDLKSPFITSGIRIGTAAVTRRGFKENEVSRISDWITS 388
>Q6MLK1:GLYA_BDEBA Serine hydroxymethyltransferase - Bdellovibrio bacteriovorus| Length = 415 Score = 334 bits (857), Expect = 7e-91 Identities = 182/399 (45%), Positives = 244/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L +VDPEI I E RQ GLE+I SEN+TS +VM+A GS++TNKY+EGYPG RYYGG Sbjct: 8 LAQVDPEILAAINKESERQQFGLEMIASENYTSKAVMEAQGSILTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 +D E+L +RA + F + NVQP SGS AN VY A K + I+ +DL H Sbjct: 68 CVNVDTVESLAIERAKKLFGVQY----ANVQPHSGSQANMGVYLAACKAGETILGMDLSH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + F+ Y+LD TG ++YD + +A +PKLI+AG SAY Sbjct: 124 GGHLTHG-----SPVNFSGMLFKAASYKLDPETGRLNYDTIRATAKEVQPKLIIAGYSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + ++I D+ A LL DMAH +GLVA G PSP YAD +TTTTHK+LRGPRG Sbjct: 179 PRTLDFAKFKEIADEVGAQLLVDMAHFAGLVATGHHPSPVPYADYITTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI K +N+ +FPG+QGGP H I G AVA +A E++ Sbjct: 239 MILTNSEEK-------------AKTMNSRIFPGIQGGPLEHVIAGKAVAFGEALKPEFKD 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +V+SN+ AE L S G+ +V+GGTDNHL+LV+L + I G E L+ I NK Sbjct: 286 YSGKVVSNAKVLAEELLSAGFKLVTGGTDNHLILVDLSDREITGKLAENSLDEAGITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NTVP + S V G+R+GTPALT+RG + ++A++ Sbjct: 346 NTVPNEKRSPFVTSGVRIGTPALTTRGMGPAEMKQIAKW 384
>P34895:GLYA_HYPME Serine hydroxymethyltransferase - Hyphomicrobium methylovorum| Length = 434 Score = 334 bits (856), Expect = 9e-91 Identities = 187/418 (44%), Positives = 252/418 (60%), Gaps = 1/418 (0%) Frame = +3 Query: 162 MASLPATEERSAVTWPKQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQ 341 M+S PA S + K + + E DP+I I+ E RQ +ELI SEN S +V+ Sbjct: 1 MSSAPAAGTASTSRFFK---SHVSETDPDIFSAIQKEFGRQQHEIELIASENIVSQAVLD 57 Query: 342 AVGSVMTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPA 521 A GSV+TNKY+EGYPG RYYGG +Y+D+ E + RA + FN + NVQP SGS A Sbjct: 58 AAGSVLTNKYAEGYPGKRYYGGCQYVDIVEDIAIDRAKKLFNCE----FANVQPNSGSQA 113 Query: 522 NFHVYTALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDY 701 N V+ AL +P D I+ L L GGHL+HG ++ +F+ + Y + + LID Sbjct: 114 NQGVFNALAQPGDTILGLSLAAGGHLTHG-----APVNQSGKWFKAVHYMVKPDSHLIDM 168 Query: 702 DQLEKSAVLFRPKLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPS 881 D++ K A +P++I+AG SAY R D+ R I D+ A+ L DMAH +GLVAAG+IPS Sbjct: 169 DEVRKLAQEHKPRIIIAGGSAYPRKIDFAAFRAIADEVGAIFLVDMAHFAGLVAAGLIPS 228 Query: 882 PFEYADVVTTTTHKSLRGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGP 1061 PF +A VVTTTTHK+LRGPRG MI D KIN+A+FPG+QGGP Sbjct: 229 PFPHAHVVTTTTHKTLRGPRGGMILTNDA-------------DIAKKINSAIFPGIQGGP 275 Query: 1062 HNHTITGLAVALKQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLK 1241 H I G AVA +A +++ Y +QVM N+ E L G+ +VSGGTD HLVLV+L+ Sbjct: 276 LMHVIAGKAVAFGEALRPDFKVYIKQVMDNARALGEVLVQNGFALVSGGTDTHLVLVDLR 335 Query: 1242 KKGIDGSRVEKVLENVHIAANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 K + G++ EK L +I NKN +P D MV GIR+G+PA T+RGF +F ++ Sbjct: 336 PKKLTGTKAEKALGRANITCNKNGIPFDPEKPMVTSGIRLGSPAGTTRGFGVAEFQEI 393
>Q7W400:GLYA2_BORPA Serine hydroxymethyltransferase 2 - Bordetella parapertussis| Length = 415 Score = 334 bits (856), Expect = 9e-91 Identities = 189/457 (41%), Positives = 263/457 (57%), Gaps = 1/457 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N L++VDP++ I+ E RQ + +ELI SEN+ S +VMQA G+ +TNKY+EGYPG RY Sbjct: 5 NLTLDQVDPDVWAAIQKEDVRQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRY 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG EY+D+ E L R + F + NVQP SGS AN VY A+LKP D ++ + Sbjct: 65 YGGCEYVDVVEQLAIDRLKQIFGAE----AANVQPNSGSQANQGVYMAVLKPGDTVLGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG ++A + +PY LD ++DY Q+E+ +PKLIVAGA Sbjct: 121 LAEGGHLTHG-----ASVNASGKLYNFVPYGLDADE-VLDYAQVERLTKEHKPKLIVAGA 174 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAYA D+ RM +I A+ + D+AH +GLVA G P+P +AD VT+TTHKSLRGP Sbjct: 175 SAYALHIDFERMARIAHDNGALFMVDIAHYAGLVAGGAYPNPVPHADFVTSTTHKSLRGP 234 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I +K + E +N+A+FPG+QGGP H I AVA K+A + E Sbjct: 235 RGGVIM--------------MKAEVEKAVNSAIFPGIQGGPLMHVIAAKAVAFKEALSPE 280 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y +QV+ N+ A++L +G IVSG T++H++LV+L+ KGI G E VL HI Sbjct: 281 FQDYAQQVVKNAKVLADTLVKRGLRIVSGRTESHVMLVDLRPKGITGKEAEAVLGQAHIT 340 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGT 1475 NKN +P D V GIR+GTPA+T+RGF E + A Sbjct: 341 VNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTA-------------------- 380 Query: 1476 KLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 + +A + + +A IA +R V E + P G Sbjct: 381 ---NLIADVLDNPRDEANIAAVRARVNELTARLPVYG 414
>Q6LU17:GLYA1_PHOPR Serine hydroxymethyltransferase 1 - Photobacterium profundum| (Photobacterium sp. (strain SS9)) Length = 416 Score = 334 bits (856), Expect = 9e-91 Identities = 185/397 (46%), Positives = 245/397 (61%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D E+ I+ E ARQ + +ELI SEN+TS VM+A GS +TNKY+EGYPG RYYGG Sbjct: 8 IADYDAELFAAIQEETARQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D AE L RA + F + NVQP SGS AN VY ALL P D ++ + L H Sbjct: 68 CEFVDKAEQLAIDRACQLFGAEY----ANVQPHSGSQANNAVYMALLNPGDTVLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + +PY +DE TG IDY+++E A+ +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIIPYGIDE-TGQIDYEEMEALALEHKPKMIIGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ RMR+I DK A DMAH++GL+AAGV P+P +A VVTTTTHK+L GPRG Sbjct: 178 SQVVDWKRMREIADKVGAYFFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I G E Y K+N+AVFPG QGGP H I AVA K+A E++ Sbjct: 238 LILSNDG---------EALY---KKLNSAVFPGGQGGPLMHVIAAKAVAFKEAMEPEFKV 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ V+ N+ +GY IVSG T+NHL LV+L KGI G + L +I NK Sbjct: 286 YQACVVENAKAMVGEFLERGYKIVSGSTENHLFLVDLIDKGITGKEADAALGAANITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V GIR+GTP++T RGF ED ++A Sbjct: 346 NSVPNDPRSPFVTSGIRIGTPSITRRGFTVEDTKQLA 382
>Q4L7Z4:GLYA_STAHJ Serine hydroxymethyltransferase - Staphylococcus haemolyticus (strain| JCSC1435) Length = 412 Score = 333 bits (855), Expect = 1e-90 Identities = 179/397 (45%), Positives = 251/397 (63%), Gaps = 2/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 ++ D + + I+ E RQ +ELI SENF S +VM+A GSVMTNKY+EGYPG RYYGG Sbjct: 4 IQNQDKAVYEAIQNEYNRQNNNIELIASENFVSEAVMEAQGSVMTNKYAEGYPGRRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 +Y+D+ ET+ +RA F + VNVQP SGS AN VY L+ D ++ ++L H Sbjct: 64 CDYVDVTETIAIERAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ F+ + Y +D+ T IDY+ + + A +PKLIVAG SAY Sbjct: 120 GGHLTHG-----SPVNFSGKFYNFVDYGVDKETEKIDYEVVRQLAHEHKPKLIVAGTSAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R D+ + ++I D+ A L+ DMAHI+GLVAAG+ P+P E+AD VTTTTHK+LRGPRG Sbjct: 175 SRQLDFKKFKEIADEVGAKLMVDMAHIAGLVAAGLHPNPVEHADFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I K +++ I+ +FPG+QGGP H I AVA +A Q+++ Sbjct: 235 LIL--------------CKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALEQDFKV 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAAN 1304 YQEQV+ N+ +++L +G+ IVSGGTDNHL+ V++K + G E L+++ I N Sbjct: 281 YQEQVIKNAKVLSQTLQEEGFRIVSGGTDNHLLSVDVKNSVNVTGKEAEATLDSIGITCN 340 Query: 1305 KNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 KNT+P D A V GIR+GTP T+RGF EE F +V Sbjct: 341 KNTIPFDQEKAFVTSGIRLGTPTATTRGFDEEAFKEV 377
>Q31CS4:GLYA_PROM9 Serine hydroxymethyltransferase - Prochlorococcus marinus (strain MIT| 9312) Length = 423 Score = 333 bits (854), Expect = 2e-90 Identities = 184/398 (46%), Positives = 254/398 (63%), Gaps = 1/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L++ DP I++ I EK RQ LELI SENF S++VMQA GSV+TNKY+EG P RYYGG Sbjct: 7 LKKSDPVISNFINSEKNRQETHLELIASENFASIAVMQAQGSVLTNKYAEGLPQKRYYGG 66 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L +RA + FN + W NVQP SG+ AN V+ +LL+P D IM +DL H Sbjct: 67 CEFVDEIEELAIQRAKKLFNAN---WA-NVQPHSGAQANAAVFLSLLQPGDTIMGMDLSH 122 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y +++ T +++D++ + A+ +PKLI+ G SAY Sbjct: 123 GGHLTHG-----SPVNMSGKWFNAVHYGVNKETSELNFDEIREIALETKPKLIICGYSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ R I D+ A L+AD+AHI+GLVA+ + P+P Y DVVTTTTHK+LRGPRG Sbjct: 178 PRTIDFESFRNIADEVGAFLMADIAHIAGLVASKLHPNPLPYCDVVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + G +F K + +VFPG QGGP H I AVA +A ++ Sbjct: 238 LILCKDG-------------EFGKKFDKSVFPGTQGGPLEHIIAAKAVAFGEALQPDFVN 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +QV+ N+ A +L S+G DIVSGGTDNH+VL++L+ + G + ++ V+I ANK Sbjct: 285 YSQQVIKNAKVLASTLISRGIDIVSGGTDNHIVLLDLRSINMTGKIADLLVSAVNITANK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 NTVP D S V G+R+GT ALT+RGF E FA+V E Sbjct: 345 NTVPFDPESPFVTSGLRLGTAALTTRGFNETAFAEVGE 382
>Q2G646:GLYA_NOVAD Serine hydroxymethyltransferase - Novosphingobium aromaticivorans| (strain DSM 12444) Length = 436 Score = 333 bits (853), Expect = 2e-90 Identities = 187/396 (47%), Positives = 242/396 (61%), Gaps = 1/396 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE D E+ I E RQ +ELI SEN TSL+V++A GSV TNKY+EGYPG RYYGG Sbjct: 20 LETADAEVFAAIRGELKRQQTKIELIASENITSLAVLEATGSVFTNKYAEGYPGKRYYGG 79 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY D+ E L +RA + F + NVQP SGS N V+ ALL+P D M LDL Sbjct: 80 CEYADVVENLAIERAKKLFGCN----FANVQPNSGSQMNQAVFLALLQPGDSFMGLDLNS 135 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F+ +PY + LID D++ + A +PKLI+AG +AY Sbjct: 136 GGHLTHG-----SPVNMSGKWFKPIPYGVRADDHLIDMDEVARLARENKPKLIIAGGTAY 190 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R++D+ R R+I D+ A LL DM+H SGLVA G PSPF +A VVT+TTHKSLRGPR Sbjct: 191 SRVWDFKRFREIADEVGAWLLVDMSHFSGLVAGGAHPSPFPHAHVVTSTTHKSLRGPRSG 250 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I D K N AVFPG+QGGP H I AVA +A E++A Sbjct: 251 IILTN-------------DEDLAKKFNMAVFPGMQGGPLVHVIAAKAVAFGEALRPEFKA 297 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y Q+++N+ AE++ G +VSGGTDNHL+LV+L K + G EK L+ + NK Sbjct: 298 YAAQIVANARALAEAVKDAGLSVVSGGTDNHLMLVDLSAKDVTGKAAEKGLDRAWLTCNK 357 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 N VP D S V GIR+GTPA T+RGF EE+F K+ Sbjct: 358 NGVPFDKRSPFVTSGIRLGTPAGTTRGFREEEFRKI 393
>Q7W1I6:GLYA1_BORPA Serine hydroxymethyltransferase 1 - Bordetella parapertussis| Length = 430 Score = 333 bits (853), Expect = 2e-90 Identities = 188/399 (47%), Positives = 240/399 (60%), Gaps = 1/399 (0%) Frame = +3 Query: 225 PLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYG 404 PL DPEI ++ E+ RQ +ELI SENF S +V+ A GSVMTNKY+EGYPG RYYG Sbjct: 18 PLRHADPEIWRAVDAERQRQMHSIELIASENFVSQAVLDAQGSVMTNKYAEGYPGRRYYG 77 Query: 405 GNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLP 584 G ++D+AE +RA F + NVQP SGS AN VY ALL P DRI+ LDL Sbjct: 78 GCRHVDVAERAAIERARRLFGCEY----ANVQPHSGSQANQAVYLALLAPGDRILGLDLK 133 Query: 585 HGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASA 764 GGHL+HG +++ +FE + Y +D + ID D++E++A RP+LI+AG SA Sbjct: 134 AGGHLTHG-----ARVNLSGKWFEALSYGVDPVSHRIDMDEVERTARRERPRLIIAGGSA 188 Query: 765 YARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRG 944 YAR+ D+ R R I D A+ +ADMAH +GLVA G PSP +A V TTTTHK+LRGPRG Sbjct: 189 YARVPDFARFRAIADATGALFVADMAHYAGLVAGGAFPSPVPFAHVTTTTTHKTLRGPRG 248 Query: 945 AMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 MI D +I+AAVFPGLQGGP H I AVAL +A +R Sbjct: 249 GMILTDDA-------------DIARRIDAAVFPGLQGGPLMHVIAAKAVALGEALQPGFR 295 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAAN 1304 AY V+ N+ L G IVSGGTD HL +V+L+ G+ G+ E+ LE I N Sbjct: 296 AYARAVIDNARALCARLAEGGLSIVSGGTDCHLGVVDLRPWGLAGNAAERALEEAGITVN 355 Query: 1305 KNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 KN VPGD S V GIR+G+ A TSRG +F ++ + Sbjct: 356 KNAVPGDAASPAVTSGIRVGSAACTSRGMGPAEFRQIGD 394
>Q3SRV3:GLYA_NITWN Serine hydroxymethyltransferase - Nitrobacter winogradskyi (strain| Nb-255 / ATCC 25391) Length = 433 Score = 332 bits (851), Expect = 3e-90 Identities = 188/396 (47%), Positives = 241/396 (60%), Gaps = 1/396 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L E DPEIA I E RQ +ELI SEN S +V++A GSVMTNKY+EGYPGARYYGG Sbjct: 19 LAEADPEIAAAITGELGRQRHEIELIASENIVSRAVLEAQGSVMTNKYAEGYPGARYYGG 78 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AETL +RA + F NVQP SGS N V+ ALL+P D M LDL Sbjct: 79 CEWVDVAETLAIERAKKLFGAR----FANVQPNSGSQMNQAVFLALLQPGDTFMGLDLAA 134 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F+ Y + LID D++ + A +PKLI+AG SAY Sbjct: 135 GGHLTHG-----APVNMSGKWFKVAHYTVRRDDHLIDMDEVARRAEEVKPKLIIAGGSAY 189 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R +D+ R R+I D A L+ DMAH +GLVA GV SP +A V TTTTHKSLRGPRG Sbjct: 190 SRPWDFKRFREIADSVGAYLMVDMAHFAGLVAGGVHASPVPHAHVTTTTTHKSLRGPRGG 249 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I K N+A+FPGLQGGP H I AVAL +A +++ Sbjct: 250 LILCNDEA-------------LAKKFNSAIFPGLQGGPLMHVIAAKAVALGEALRPDFKI 296 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y + V+ N+ AESL G+DIVSGGTDNHL+LV+L+ KG+ G+ EK L + NK Sbjct: 297 YAKNVVENARALAESLRGHGFDIVSGGTDNHLMLVDLRPKGLKGNVSEKALVRAGLTCNK 356 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 N +P D V G+R+GTPA T+RGF +F +V Sbjct: 357 NGIPFDPEKPFVTSGLRLGTPATTTRGFGVSEFKQV 392
>Q74LC1:GLYA_LACJO Serine hydroxymethyltransferase - Lactobacillus johnsonii| Length = 411 Score = 332 bits (851), Expect = 3e-90 Identities = 184/397 (46%), Positives = 249/397 (62%), Gaps = 2/397 (0%) Frame = +3 Query: 234 EVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNE 413 E P + D I+ E+ RQ +ELI SEN S +V +A GSV+TNKY+EGYPG RYYGG + Sbjct: 5 EKSPALWDAIKSEEKRQEDTIELIASENIVSDAVREAQGSVLTNKYAEGYPGKRYYGGCQ 64 Query: 414 YIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGG 593 YID E L A + FN + NVQP SGS AN VY ALLKP D I+ + + GG Sbjct: 65 YIDKVEQLAIDYAKKLFNAEY----ANVQPHSGSQANMTVYNALLKPGDTILGMGMDAGG 120 Query: 594 HLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYAR 773 HL+HG K++ F ++ Y L+ T +D+D++ + A+ +PKLI+AGASAY+R Sbjct: 121 HLTHG-----SKVNFSGKIFNSISYDLNPETEELDFDRIRQLAIEKKPKLIIAGASAYSR 175 Query: 774 LYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMI 953 + D+ + R+I D+ A L+ DMAHI+GLVA G PSP ADVVTTTTHK+LRGPRG MI Sbjct: 176 IIDWQKFREIADEVGAYLMVDMAHIAGLVATGAHPSPVPIADVVTTTTHKTLRGPRGGMI 235 Query: 954 FFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQ 1133 KE+ K KI++A+FPG QGGP H I A A + E+ Y Sbjct: 236 LSNN--KELGK-----------KIDSALFPGTQGGPLEHVIAAKAQAFYEDLQPEFTQYI 282 Query: 1134 EQVMSNSARFAESL-TSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKN 1310 +QV+ NS AE SK +VSGGTDNHL+++++ K G+ G + +L++V+I NK Sbjct: 283 DQVIKNSKAMAEEFKNSKNIRVVSGGTDNHLMIIDITKTGVTGKDAQNLLDSVNITTNKE 342 Query: 1311 TVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 ++PGD S + G+R+GTPA+TSRGF E D +VA+ Sbjct: 343 SIPGDKRSPFITSGLRIGTPAITSRGFKEPDAKEVAK 379
>O51547:GLYA_BORBU Serine hydroxymethyltransferase - Borrelia burgdorferi (Lyme disease| spirochete) Length = 417 Score = 332 bits (851), Expect = 3e-90 Identities = 187/396 (47%), Positives = 247/396 (62%), Gaps = 2/396 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D +I ++IE EK R+ + +ELI SENFTSL + QAVGS++TNKY+EGYP RYYGG +I Sbjct: 3 DDQIFNLIEKEKLREREHIELIASENFTSLEIRQAVGSILTNKYAEGYPLNRYYGGCSFI 62 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D ETL RA E F NVQP SGS AN AL+ P DRI+ + L HGGHL Sbjct: 63 DEIETLAISRAKELFGAKY----ANVQPHSGSQANMAAIMALISPGDRILGMQLSHGGHL 118 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG +++ IFF T Y + + LIDYD++ K A RP LI+AGAS+Y+R Sbjct: 119 THG-----SRVNFSGIFFNTYFYGVSRDSELIDYDEVLKIAKDCRPNLIIAGASSYSREI 173 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + R+I D A LL D+AHI+GL+ AG S + A + T+TTHK+LRGPRG +I Sbjct: 174 DFKKFREIADDVSAYLLCDIAHIAGLIVAGFHNSSIDVAHLTTSTTHKTLRGPRGGIILS 233 Query: 960 RKGV-KEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQE 1136 K K +N GKE + +N+ VFPG QGGP H I G A+A K+A + ++ Y Sbjct: 234 GKDFDKLVNFNGKE--KPLFNAVNSTVFPGTQGGPLVHVIAGKAIAFKEALQESFKEYIA 291 Query: 1137 QVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTV 1316 V+ N+ AE S+G+ IVSGGTDNHL LV+L + G+ EK+LE+V+I NKN + Sbjct: 292 NVIKNTKVMAEYFKSEGFRIVSGGTDNHLFLVDLSSSDLTGADAEKLLESVNITLNKNAI 351 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 P D S + GIR+G A+TSRG E D VA+F Sbjct: 352 PFDKKSPSLASGIRIGGAAITSRGLNESDSLNVAKF 387
>Q5WB66:GLYA_BACSK Serine hydroxymethyltransferase - Bacillus clausii (strain KSM-K16)| Length = 417 Score = 332 bits (851), Expect = 3e-90 Identities = 180/398 (45%), Positives = 250/398 (62%), Gaps = 1/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ DP + + I E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 4 LKTQDPAVFEAIRQELGRQRDKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+AE + + RA + F VNVQP SG+ AN VY +L+ D ++ ++L H Sbjct: 64 CEYVDIAEDVARDRAKQLFGAAY----VNVQPHSGAQANMGVYFTILEHGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ I + + Y + E IDY+ + ++A +PKLIVAGASAY Sbjct: 120 GGHLTHG-----SPVNFSGIQYRFVEYGVREDDKRIDYEAVREAAKTHQPKLIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + R+I D+ A L+ DMAHI+GLVAAG+ +P YA VTTTTHK+LRGPRG Sbjct: 175 PREIDFKKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPYAHFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI +E +F K++ ++FPG+QGGP H I AVA +A + E++ Sbjct: 235 MILC----------NEETAEEFGKKLDKSIFPGIQGGPLMHVIAAKAVAFGEALSDEFKT 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +Q+++N+ R E L ++G DIVSGGTDNHL+L++L+ + G EK L+ V I NK Sbjct: 285 YAKQIIANAKRLGEKLQAEGVDIVSGGTDNHLLLLDLRSLQLTGKVAEKALDAVGITTNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 N +P D V GIR+GT A+TSRGF E + ++ E Sbjct: 345 NAIPFDPEKPFVTSGIRIGTAAVTSRGFGENEMDEIGE 382
>Q6MS85:GLYA_MYCMS Serine hydroxymethyltransferase - Mycoplasma mycoides subsp. mycoides| SC Length = 413 Score = 332 bits (850), Expect = 5e-90 Identities = 179/395 (45%), Positives = 252/395 (63%), Gaps = 2/395 (0%) Frame = +3 Query: 234 EVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNE 413 ++ P I + + E RQ +ELI SEN+ S +V++ GSV+TNKY+EGYPG RYYGG E Sbjct: 4 KISPLIKESLNKELKRQQSHIELIASENYVSKAVLELNGSVLTNKYAEGYPGKRYYGGCE 63 Query: 414 YIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGG 593 +ID E+L + A E F+ + N+QP SGS AN Y ALL+P DR++A+ L GG Sbjct: 64 FIDEIESLGIQTAKELFHAEH----ANIQPHSGSQANDAAYKALLEPKDRVVAMSLDAGG 119 Query: 594 HLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYAR 773 HL+HGY I+ ++ Y +++ T +DY ++EK + +PKLIVAGASAY+R Sbjct: 120 HLTHGYP-----INFSGYTYDFRFYGVNKDTEQLDYQEIEKIVLEHKPKLIVAGASAYSR 174 Query: 774 LYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMI 953 + D+ + ++I DK A L+ DMAHI+GLVAAGV P+P EYAD+VTTTTHK+LRG RG +I Sbjct: 175 IIDFKKFKEIADKVGAYLMVDMAHIAGLVAAGVHPNPLEYADIVTTTTHKTLRGARGGLI 234 Query: 954 FFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQ 1133 K +F K++ AVFPG QGGP + I G AL +A+T E++ Y Sbjct: 235 L--------------CKQEFAKKVDLAVFPGSQGGPLENLIAGKTQALLEASTDEFKEYG 280 Query: 1134 EQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKN 1310 +Q++ N+ A L G +V+GG+DNHL+ V++K I G + EK+LE++ I NKN Sbjct: 281 KQIVKNTKALANVLQENGLRLVAGGSDNHLINVDVKSTLRITGKKAEKILESIGIICNKN 340 Query: 1311 TVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 +P D GIR+GTPA+T+RGF EE+F +V Sbjct: 341 MIPFDTEKPFYTSGIRLGTPAMTTRGFKEEEFKQV 375
>Q9K6G4:GLYA_BACHD Serine hydroxymethyltransferase - Bacillus halodurans| Length = 413 Score = 332 bits (850), Expect = 5e-90 Identities = 178/391 (45%), Positives = 251/391 (64%), Gaps = 1/391 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ DP++ + ++ E RQ +ELI SENF S +VM+A SV+TNKY+EGYPG RYYGG Sbjct: 4 LQSKDPKVFEAVQQELGRQRDKIELIASENFVSEAVMEAQSSVLTNKYAEGYPGRRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L + RA E F + VNVQP SG+ AN VY +L+ D ++ ++L H Sbjct: 64 CEYVDIVEDLARDRAKEIFGGEH----VNVQPHSGAQANMAVYFTILEHGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ I + + Y +D+ + IDY+++ + A +PK+IVAGASAY Sbjct: 120 GGHLTHG-----SPVNFSGIQYNFVEYGVDKESQRIDYEEVRRLAKEHQPKMIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + R+I D+ A L+ DMAHI+GLVAAG+ +P ++ VTTTTHK+LRGPRG Sbjct: 175 PREIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPHSHFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI + +F +I+ ++FPG+QGGP H I AVA +A E+++ Sbjct: 235 MIICNE--------------EFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQPEFKS 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y E ++ N+ R E LTS+G D+VSGGTDNHL+L++L+ G+ G EK L++V I NK Sbjct: 281 YGEAIIRNAKRLGEKLTSEGIDLVSGGTDNHLLLLDLRSLGLTGKVAEKALDDVGITTNK 340 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEE 1397 NT+P D S V GIR+GT A+TSRG EE Sbjct: 341 NTIPFDPESPFVTSGIRIGTAAVTSRGLDEE 371
>Q7WPH6:GLYA1_BORBR Serine hydroxymethyltransferase 1 - Bordetella bronchiseptica| (Alcaligenes bronchisepticus) Length = 430 Score = 332 bits (850), Expect = 5e-90 Identities = 188/399 (47%), Positives = 239/399 (59%), Gaps = 1/399 (0%) Frame = +3 Query: 225 PLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYG 404 PL DPEI ++ E+ RQ +ELI SENF S +V+ A GSVMTNKY+EGYPG RYYG Sbjct: 18 PLRHADPEIWRAVDAERQRQMHSIELIASENFVSQAVLDAQGSVMTNKYAEGYPGRRYYG 77 Query: 405 GNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLP 584 G ++D+AE +RA F + NVQP SGS AN VY ALL P DRI+ LDL Sbjct: 78 GCRHVDVAERAAIERARRLFGCEY----ANVQPHSGSQANQAVYLALLAPGDRILGLDLK 133 Query: 585 HGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASA 764 GGHL+HG ++ +FE + Y +D + ID D++E++A RP+LI+AG SA Sbjct: 134 AGGHLTHGAH-----VNLSGKWFEALSYGVDPVSHRIDMDEVERTARRERPRLIIAGGSA 188 Query: 765 YARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRG 944 YAR+ D+ R R I D A+ +ADMAH +GLVA G PSP +A V TTTTHK+LRGPRG Sbjct: 189 YARVPDFARFRAIADATGALFVADMAHYAGLVAGGAFPSPVPFAHVTTTTTHKTLRGPRG 248 Query: 945 AMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYR 1124 MI D +I+AAVFPGLQGGP H I AVAL +A +R Sbjct: 249 GMILTDDA-------------DIARRIDAAVFPGLQGGPLMHVIAAKAVALGEALQPGFR 295 Query: 1125 AYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAAN 1304 AY V+ N+ L G IVSGGTD HL +V+L+ G+ G+ E+ LE I N Sbjct: 296 AYARAVIDNARALCARLAEGGLSIVSGGTDCHLGVVDLRPWGLAGNAAERALEEAGITVN 355 Query: 1305 KNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 KN VPGD S V GIR+G+ A TSRG +F ++ + Sbjct: 356 KNAVPGDAASPAVTSGIRVGSAACTSRGMGPAEFRQIGD 394
>Q65T08:GLYA_MANSM Serine hydroxymethyltransferase - Mannheimia succiniciproducens| (strain MBEL55E) Length = 420 Score = 331 bits (849), Expect = 6e-90 Identities = 191/457 (41%), Positives = 267/457 (58%), Gaps = 1/457 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N + E DP + D I+ E RQ + +ELI SEN+ + +VM+A GS +TNKY+EGYPG RY Sbjct: 4 NHSIAEFDPVLWDAIQNENRRQEEHIELIASENYVTKAVMEAQGSQLTNKYAEGYPGKRY 63 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG EY+D+ E L RA E F D NVQP SGS AN VY ALL D I+ +D Sbjct: 64 YGGCEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANAAVYGALLNAGDTILGMD 119 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG K+S + ++ Y + + GLIDY+ + A+ +PK+IVAG Sbjct: 120 LAHGGHLTHG-----AKVSFSGKIYNSVLYGIT-AEGLIDYEDVRVKALESKPKMIVAGF 173 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY+++ D+ +MR+I D+ A L DMAH++GL+AAG+ P+P +A VVTTTTHK+L GP Sbjct: 174 SAYSQVVDWAKMREIADEVGAYLFVDMAHVAGLIAAGLYPNPLPHAHVVTTTTHKTLAGP 233 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I G +EI K K+N++VFP QGGP H I AV K+A E Sbjct: 234 RGGLILSACGDEEIYK-----------KLNSSVFPANQGGPLMHVIAAKAVCFKEALQPE 282 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++AYQ QV+ N+ E +G+++VS GT+NHL LV+ K+G+ G + L +I Sbjct: 283 FKAYQAQVLKNAKAMVEVFKQRGFEVVSKGTENHLFLVSFVKQGLTGKAADAALGEANIT 342 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGT 1475 NKN+VP D + GIR+G+P++T RGF E D + +A + Sbjct: 343 VNKNSVPNDPQKPFITSGIRVGSPSITRRGFNEADASTLAGW------------------ 384 Query: 1476 KLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 + D + ++ D N IA+ R V E K+ P G Sbjct: 385 -MCDVLESIGKD-NYDQVIAETRAKVLEICKRLPVYG 419
>Q3SGX5:GLYA_THIDA Serine hydroxymethyltransferase - Thiobacillus denitrificans (strain| ATCC 25259) Length = 414 Score = 331 bits (848), Expect = 8e-90 Identities = 187/454 (41%), Positives = 262/454 (57%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L + DP++ I+ E RQ +ELI SEN+TS +VMQA GS +TNKY+EGYPG RYYGG Sbjct: 8 LAKTDPDLWAAIQQEDRRQQDHIELIASENYTSPAVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L R F + NVQP SGS AN V+ A LKP D IM + L Sbjct: 68 CEYVDIVEQLAIDRVKALFGAE----AANVQPNSGSQANQAVFMAFLKPGDTIMGMSLAE 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y L+E IDY+ +E+ A +PKLI+AGASAY Sbjct: 124 GGHLTHGMA-----LNMSGKWFNVVAYGLNEKEE-IDYEAMERLAREHKPKLIIAGASAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 A D+ R KI + A+ + DMAH +GL+AAG+ P+P +ADVVT+TTHK+LRGPRG Sbjct: 178 ALRIDFERFAKIAKEIGAIFMVDMAHYAGLIAAGLYPNPVPHADVVTSTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +K + E IN+A+FPGLQGGP H I G A A K+A T++++ Sbjct: 238 IIL--------------MKAEHEKAINSAIFPGLQGGPLMHVIAGKATAFKEAATKDFKR 283 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQEQV+ N+ + L +G I+SG T++H+ LV+L+ K + G E +L HI NK Sbjct: 284 YQEQVIDNALVMCKVLVERGLRIISGRTESHVFLVDLRAKNLTGKEAEALLGRAHITVNK 343 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D V GIR+GTPA+T+RGF E + ++A Sbjct: 344 NAIPNDPQKPFVTSGIRIGTPAMTTRGFTELEAEQLAH---------------------- 381 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 +A + N +A + +++ +V + +FP G Sbjct: 382 -LIADVLDAPNDEAVVERVKGEVAKLTAKFPVYG 414
>Q30P60:GLYA2_THIDN Serine hydroxymethyltransferase 2 - Thiomicrospira denitrificans| (strain ATCC 33889 / DSM 1351) Length = 420 Score = 330 bits (847), Expect = 1e-89 Identities = 193/397 (48%), Positives = 242/397 (60%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE D E+ IIE E RQ LE+I SENFTS +VM+A+GSV TNKY+EGYP RYYGG Sbjct: 9 LEHADREVFSIIEGELKRQTAHLEMIASENFTSPAVMEAMGSVFTNKYAEGYPYKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY D E L RA E F NVQP SGS AN VY ALLK D+++ +DL H Sbjct: 69 CEYADAVEQLAIDRACEIFGCK----FANVQPHSGSQANAAVYAALLKAGDKLLGMDLSH 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K S + + Y + E+ G +DYD++ + A +PK+IV GASAY Sbjct: 125 GGHLTHG-----SKPSFSGQNYSSFTYGV-EADGRMDYDKILEIAKAVQPKIIVCGASAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 AR D+ + R+I D A L AD+AH++GLVAA SPF +A VVTTTTHK+LRGPRG Sbjct: 179 AREIDFKKFREIADAVGAFLFADIAHVAGLVAADEHMSPFPHAHVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI +EI K KIN+A+FPG+QGGP H I AVA K+ +R Sbjct: 239 MIM--TDDEEIAK-----------KINSAIFPGIQGGPLVHVIAAKAVAFKEILDPSWRE 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +QV +N+ LT +GYD+VSGGTDNHLVLV+ + G + LE I NK Sbjct: 286 YAKQVKANAKVLEVVLTKRGYDLVSGGTDNHLVLVSFLNRDFSGKDADAALERAGITVNK 345 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N VP D S + GIR+G+PALT+RG E +F +A Sbjct: 346 NGVPNDTRSPFITSGIRIGSPALTARGMKEAEFELIA 382
>Q9PET2:GLYA_XYLFA Serine hydroxymethyltransferase - Xylella fastidiosa| Length = 417 Score = 330 bits (846), Expect = 1e-89 Identities = 185/402 (46%), Positives = 249/402 (61%), Gaps = 1/402 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 +A L+ DPE+A I E RQ +ELI SEN+ S VMQ GS +TNKY+EGY G RY Sbjct: 5 DARLDMYDPELAKAIAAEVMRQEDHVELIASENYCSTLVMQVQGSQLTNKYAEGYSGKRY 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG E +D+AE L +RA + F D NVQP SGS AN VY ALL+P D I+ + Sbjct: 65 YGGCECVDIAEQLAIERAKQLFGADY----ANVQPHSGSQANQAVYFALLQPGDTILGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG ++ F + Y ++ GLIDY+ +E A+ RPK++VAG Sbjct: 121 LAHGGHLTHG-----ANVNVSGKLFNAVQYGVN-GQGLIDYEAVESLALEHRPKMVVAGF 174 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY++ D+ R R I D+ A LL DMAH++GLVAA V P+P +A VVT+TTHK+LRGP Sbjct: 175 SAYSQKIDWARFRAIADQVGAYLLVDMAHVAGLVAACVYPNPLPHAHVVTSTTHKTLRGP 234 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I + + + K K+ + VFPG+QGGP H I AVA K+A Sbjct: 235 RGGIIVAQAPQEALVK-----------KLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPA 283 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ YQ+QV+ N+ AE+L +GY IVSGGT+NHL+LV++ + + G E L HI Sbjct: 284 FKVYQQQVVKNAKAMAETLMLRGYKIVSGGTENHLMLVDMIGRDVSGKDAEGALGQAHIT 343 Query: 1299 ANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NKN VP D S V G+R+GTPA+T+RG+ E+D +A + Sbjct: 344 VNKNAVPDDPRSPFVTSGLRLGTPAVTTRGYQEQDCVDLAHW 385
>Q6N693:GLYA1_RHOPA Serine hydroxymethyltransferase 1 - Rhodopseudomonas palustris| Length = 432 Score = 330 bits (846), Expect = 1e-89 Identities = 186/399 (46%), Positives = 241/399 (60%), Gaps = 1/399 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 +A LE+ DPEIA I E RQ +ELI SEN S +V++A GSVMTNKY+EGYPG RY Sbjct: 15 SASLEQADPEIAAAIRGELGRQRHEVELIASENIVSRAVLEAQGSVMTNKYAEGYPGNRY 74 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG E++D+AE L RA + F + NVQP SGS N V+ ALL+P D M LD Sbjct: 75 YGGCEFVDVAENLAIDRAKKLFGAN----FANVQPNSGSQMNQAVFLALLQPGDTFMGLD 130 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG ++ +F+ + Y + +ID D + K A +PKLI+AG Sbjct: 131 LAAGGHLTHG-----APVNMSGKWFKPVHYTVRREDQMIDMDAVAKLAEEAKPKLIIAGG 185 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY R +D+ R R+I D A + DMAH +GLVA GV SP +A V TTTTHKSLRGP Sbjct: 186 SAYPRAWDFKRFREIADSVGAYFMVDMAHFAGLVAGGVHASPVPHAHVTTTTTHKSLRGP 245 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I K N+A+FPGLQGGP H I AVA K+A + Sbjct: 246 RGGLILTNDEA-------------LAKKFNSAIFPGLQGGPLMHVIAAKAVAFKEALQPD 292 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y + V+ N+ AE+L S G+D+VSGGTDNHL+LV+L+ KG+ G+ EK L I Sbjct: 293 FKVYTKNVVENAKALAETLRSAGFDLVSGGTDNHLMLVDLRPKGLKGNVSEKALVRAGIT 352 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NKN +P D V G+R+GTPA T+RGF +F +V Sbjct: 353 CNKNGIPFDPEKPFVTSGLRLGTPAATTRGFGVAEFQQV 391
>Q2ST43:GLYA_MYCCT Serine hydroxymethyltransferase - Mycoplasma capricolum subsp.| capricolum (strain California kid / ATCC 27343 / NCTC 10154) Length = 413 Score = 330 bits (845), Expect = 2e-89 Identities = 177/395 (44%), Positives = 254/395 (64%), Gaps = 2/395 (0%) Frame = +3 Query: 234 EVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNE 413 +++ +I + + E RQ +ELI SEN+ S +V++ GSV+TNKY+EGYPG RYYGG E Sbjct: 4 KINSKIRESLNKELKRQQSHIELIASENYVSQAVLELNGSVLTNKYAEGYPGKRYYGGCE 63 Query: 414 YIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGG 593 +ID E+L + A E F+ + N+QP SGS AN Y ALL+P DR++A+ L GG Sbjct: 64 FIDEIESLGIQTAKELFHAEH----ANIQPHSGSQANDAAYKALLEPKDRVVAMGLDAGG 119 Query: 594 HLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYAR 773 HL+HGY I+ ++ Y +++ T +DY ++E+ + +PKLIVAGASAY+R Sbjct: 120 HLTHGYP-----INFSGYTYDFRFYGVNKDTEQLDYQEIEQIVLEHKPKLIVAGASAYSR 174 Query: 774 LYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMI 953 + D+ + ++I DK A L+ DMAHI+GLVAAGV P+P EYAD+VTTTTHK+LRG RG +I Sbjct: 175 IIDFKKFKEIADKVGAYLMVDMAHIAGLVAAGVHPNPMEYADIVTTTTHKTLRGARGGLI 234 Query: 954 FFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQ 1133 K +F K+++AVFPG QGGP + I G AL +A+T E++ Y Sbjct: 235 L--------------CKQEFAKKVDSAVFPGSQGGPLENLIAGKTQALLEASTDEFKEYG 280 Query: 1134 EQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKN 1310 +Q++ N+ A L G +V+GG+DNHL+ V++K I G + EK+LE++ I NKN Sbjct: 281 KQIVKNTKALANVLQENGLRLVAGGSDNHLINVDIKSTLQITGKKAEKILESIGIICNKN 340 Query: 1311 TVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 +P D GIR+GTPA+T+RGF EE+F +V Sbjct: 341 MIPFDTEKPFYTSGIRLGTPAMTTRGFKEEEFKQV 375
>P59432:GLYA_BUCBP Serine hydroxymethyltransferase - Buchnera aphidicola subsp.| Baizongia pistaciae Length = 417 Score = 330 bits (845), Expect = 2e-89 Identities = 177/402 (44%), Positives = 255/402 (63%), Gaps = 1/402 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N + D ++ +++ E RQ +ELI SEN+ S VM+A GS +TNKY+EGYPG RY Sbjct: 5 NKTISNYDADVYRMMKQEYQRQENHIELIASENYVSSCVMEAQGSQLTNKYAEGYPGKRY 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG +Y+D E + KRA + FN + NVQP SGS AN+ VY+ALLKP+D ++ + Sbjct: 65 YGGCDYVDAIEKIAIKRAKKLFNANY----ANVQPHSGSQANYAVYSALLKPNDIVLGMS 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG ++ ++ + Y LD S G IDY Q+ K A ++PK+IV G Sbjct: 121 LSHGGHLTHG-----SSVNFSGKLYKFISYGLDIS-GDIDYPQIRKLAHRYKPKMIVGGF 174 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY+ + ++ +R+I D+ + L DMAHISGLVAAG+ P+P +YA VVT+TTHK+L GP Sbjct: 175 SAYSGICNWKLLREIADEINSYLFVDMAHISGLVAAGLYPNPLKYAHVVTSTTHKTLSGP 234 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I + + K K+N++VFPG QGGP H I A+A K+A E Sbjct: 235 RGGLILAKGDNVSLFK-----------KLNSSVFPGCQGGPLMHVIAAKAIAFKEAMEPE 283 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ YQ QV+ N+ A++ S+GY +VSG T NHL+L++L K I G R + +L + +I Sbjct: 284 FKDYQYQVIKNAQEMAKTFISRGYKVVSGKTFNHLLLLDLSNKNITGKRADILLHSANII 343 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NKN++P D +S + GIR+GTPA+T RGF E + +V+ + Sbjct: 344 VNKNSIPNDLLSPFITSGIRIGTPAITRRGFTELESRQVSNW 385
>Q2KV15:GLYA_BORA1 Serine hydroxymethyltransferase - Bordetella avium (strain 197N)| Length = 416 Score = 330 bits (845), Expect = 2e-89 Identities = 180/392 (45%), Positives = 245/392 (62%), Gaps = 1/392 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L++VDP++ I+ E RQ + +ELI SEN+ S +VMQA G+ +TNKY+EGYPG RYYGG Sbjct: 8 LDKVDPDLWAAIQKEDERQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L R E F + NVQP SGS AN VY A+LKP D ++ + L Sbjct: 68 CEYVDIVEQLAIDRLKELFGAE----AANVQPNSGSQANQGVYMAVLKPGDTVLGMSLAE 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++A + + Y LDE+ +++Y Q+E A +PKLIVAGASAY Sbjct: 124 GGHLTHG-----ASVNASGKLYNFLSYGLDENE-VLNYAQVEALAREHKPKLIVAGASAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 A D+ RM +I + A+ + D+AH +GLVA G P+P +AD VT+TTHKSLRGPRG Sbjct: 178 ALHIDFERMARIARENGALFMVDIAHYAGLVAGGQYPNPVPHADFVTSTTHKSLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +K E +N+A+FPG+QGGP H I AVA K+A + E++ Sbjct: 238 VIM--------------MKAQHEKAVNSAIFPGIQGGPLEHVIAAKAVAFKEALSPEFKD 283 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV+ N+ AE+L +G IVSG T++H++LV+L+ KGI G E VL HI NK Sbjct: 284 YASQVVKNAKVLAETLVKRGLRIVSGRTESHVMLVDLRAKGITGKEAEAVLGKAHITVNK 343 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEED 1400 N +P D V GIR+GTPA+T+RGF E + Sbjct: 344 NAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAE 375
>Q98A81:GLYA2_RHILO Serine hydroxymethyltransferase 2 - Rhizobium loti (Mesorhizobium| loti) Length = 437 Score = 330 bits (845), Expect = 2e-89 Identities = 173/402 (43%), Positives = 251/402 (62%), Gaps = 1/402 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L +VD + +++ ++ ++ L+LI SENF S +V++A GS+ NKY+EGYPGARYY G Sbjct: 12 LVQVDCRVHELLLRQRRQERTMLKLIASENFASSAVLEATGSIFANKYAEGYPGARYYAG 71 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 NE +D ETL +R F + NVQP SGSPAN VY ALL P D++M L LP Sbjct: 72 NEIVDELETLAIERLKALFGSEH----ANVQPYSGSPANQAVYRALLSPRDKVMGLPLPE 127 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG+ + ++ +PY L + T IDYD+L ++A RPKLI G ++Y Sbjct: 128 GGHLTHGWSVNFSGTD-----YQRVPYGLHDKTQQIDYDRLRETARRERPKLIWVGGTSY 182 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R++DY M +I + + L+AD+AHISGL+ AG P+P + DVVT+T+HKS+RGPRG Sbjct: 183 PRVFDYAAMAEIALEANSYLVADIAHISGLIVAGAHPNPVVHCDVVTSTSHKSIRGPRGG 242 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 I + + K++ +I+ AVFP LQGGPH +TI LAVAL++A T +R Sbjct: 243 FILSKNEDRYQALYHSTSKHNLAKRIDRAVFPQLQGGPHMNTIAALAVALQEAATPSFRT 302 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y Q++ N+ AE+L +GY +V+GGTDNH+++++L+ + + G + L I N Sbjct: 303 YGHQIVKNAKALAEALLGRGYYLVTGGTDNHMLILDLRDRPLSGKAYAERLARAGIITNF 362 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDS 1430 + VPGD V GIR+G+PA+TS G E + ++A F DS Sbjct: 363 DMVPGDPRDPTVTSGIRLGSPAVTSMGMREAEMVQIAAFIDS 404
>Q7V335:GLYA_PROMP Serine hydroxymethyltransferase - Prochlorococcus marinus subsp.| pastoris (strain CCMP 1378 / MED4) Length = 423 Score = 329 bits (844), Expect = 2e-89 Identities = 182/398 (45%), Positives = 253/398 (63%), Gaps = 1/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+E DP I+++I EK RQ LELI SENF S++VMQA GSV+TNKY+EG P RYYGG Sbjct: 7 LKESDPIISNLINSEKNRQETHLELIASENFASMAVMQAQGSVLTNKYAEGLPQKRYYGG 66 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L +RA + F+ D W NVQP SG+ AN V+ +LLKP D I+ +DL H Sbjct: 67 CEFVDEIEELAIERAKQLFDAD---WA-NVQPHSGAQANAAVFLSLLKPGDTILGMDLSH 122 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ +F + Y +D+ T ++++++ A+ +PKLI+ G SAY Sbjct: 123 GGHLTHG-----SPVNMSGKWFNAVHYGVDKETNKLNFNEIRDIALATKPKLIICGYSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ R+I D+ A L+AD+AHI+GLVA + P+P Y DVVTTTTHK+LRGPRG Sbjct: 178 PRKIDFESFRRIADEVGAFLMADIAHIAGLVATKLHPNPIPYCDVVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + KE K K + +VFPG QGGP H I AVA +A + Sbjct: 238 LILCKD--KEFGK-----------KFDKSVFPGTQGGPLEHIIAAKAVAFGEALKPNFVN 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y +QV++N+ + +L +G DIVSGGTDNH+VL++L+ + G + ++ V+I ANK Sbjct: 285 YSKQVINNAKVLSSTLIKRGIDIVSGGTDNHIVLLDLRSINMTGKVADLLVSEVNITANK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 NTVP D S V G+R+GT ALT+RGF ++ F +V E Sbjct: 345 NTVPFDPESPFVTSGLRLGTAALTTRGFNDDAFVEVGE 382
>Q2YD58:GLYA_NITMU Serine hydroxymethyltransferase - Nitrosospira multiformis (strain| ATCC 25196 / NCIMB 11849) Length = 416 Score = 329 bits (844), Expect = 2e-89 Identities = 185/397 (46%), Positives = 243/397 (61%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 LE VDP++ I+ E RQ + +ELI SEN+ S +VMQA GSV+TNKY+EGYPG RYYGG Sbjct: 8 LETVDPDLWQAIKGEMQRQEEYIELIASENYASPAVMQAQGSVLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY+D+ E L R F+ + VNVQP SGS AN VY LKP D ++ + L H Sbjct: 68 CEYVDVVEQLAIDRVRALFDAEY----VNVQPHSGSQANAAVYLTALKPGDTLLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ F + Y L T +DYD++ + A +PKLIVAGASAY Sbjct: 124 GGHLTHG-----ASVNLSGKIFNAVSYGLRSDTEELDYDEVARLAHEHKPKLIVAGASAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ R RKI D A L DMAH +GLVAAG P+P AD VT+TTHK+LRGPRG Sbjct: 179 SLVIDWKRFRKIADDIGAYLFVDMAHYAGLVAAGYYPNPVGIADFVTSTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R + E +N+A+FP QGGP H I AVA K+A +QE++ Sbjct: 239 IIMARA--------------EHEKALNSAIFPQTQGGPLMHVIAAKAVAFKEAASQEFKD 284 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQEQV+ N+ A+ L +G IVSG TD H+ LV+L+ K I G + + LE HI NK Sbjct: 285 YQEQVIDNARVMAKVLQERGLRIVSGRTDCHMFLVDLRPKYITGKQAAESLEVAHITVNK 344 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N +P D V GIR+G+PA+T+RGF E + ++A Sbjct: 345 NAIPNDPQKPFVTSGIRIGSPAITTRGFAEFESEQLA 381
>Q9X794:GLYA_MYCLE Serine hydroxymethyltransferase - Mycobacterium leprae| Length = 426 Score = 329 bits (844), Expect = 2e-89 Identities = 198/461 (42%), Positives = 265/461 (57%), Gaps = 6/461 (1%) Frame = +3 Query: 222 APLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYY 401 APL EVDP+IA+++ E RQ LE+I SENF SV+QA GSV+TNKY+EG PG RYY Sbjct: 3 APLAEVDPDIAELLGKELGRQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGLPGRRYY 62 Query: 402 GGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDL 581 G E++D+ E + + RA F D NVQP SG+ AN V AL+ P +R++ LDL Sbjct: 63 DGCEHVDVVENIARDRAKALFGAD----FANVQPHSGAQANAAVLHALMSPGERLLGLDL 118 Query: 582 PHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGAS 761 +GGHL+HG +++ +ET Y +D +T LID D + A+ FRPK+++AG S Sbjct: 119 ANGGHLTHGM-----RLNFSGKLYETGFYGVDATTHLIDMDAVRAKALEFRPKVLIAGWS 173 Query: 762 AYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPR 941 AY R+ D+ R I D+ A L DMAH +GLVA G+ PSP +ADVV+TT HK+L G R Sbjct: 174 AYPRILDFAAFRSIADEVGAKLWVDMAHFAGLVAVGLHPSPVPHADVVSTTVHKTLGGGR 233 Query: 942 GAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEY 1121 +I GK+ +F IN+AVFPG QGGP H I G AVALK ATT E+ Sbjct: 234 SGLIL-----------GKQ---EFATAINSAVFPGQQGGPLMHVIAGKAVALKIATTPEF 279 Query: 1122 RAYQEQVMSNSARFAESLTS-----KGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLEN 1286 Q++ ++ + A+ LT+ G +VSGGTD HLVLV+L+ DG E +L Sbjct: 280 TDRQQRTLAGARILADRLTAADVTKAGVSVVSGGTDVHLVLVDLRNSPFDGQAAEDLLHE 339 Query: 1287 VHIAANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXX 1463 V I N+N VP D MV G+R+GTPAL +RGF E +F +VA Sbjct: 340 VGITVNRNVVPNDPRPPMVTSGLRIGTPALATRGFGEAEFTEVA---------------- 383 Query: 1464 XXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 D +AT+ + ++A LR V A+ FP G Sbjct: 384 -------DIIATVLTTGG-SVDVAALRQQVTRLARDFPLYG 416
>Q2RTB8:GLYA2_RHORT Serine hydroxymethyltransferase 2 - Rhodospirillum rubrum (strain| ATCC 11170 / NCIB 8255) Length = 430 Score = 329 bits (844), Expect = 2e-89 Identities = 192/462 (41%), Positives = 264/462 (57%), Gaps = 1/462 (0%) Frame = +3 Query: 204 WPKQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGY 383 W +A + + DPE+ ++ E +RQ +ELI SEN S +V++A GSV+TNKY+EGY Sbjct: 7 WTGFFSASVAQADPELDRVLRAELSRQQDQIELIASENIVSRAVLEAAGSVLTNKYAEGY 66 Query: 384 PGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDR 563 PG RYYGG E +D+AE L +RA F VNVQP SG+ AN V AL+KP D Sbjct: 67 PGKRYYGGCEEVDVAEELAIERAKALFGCSY----VNVQPHSGAQANGAVMMALVKPGDT 122 Query: 564 IMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKL 743 IM + L GGHL+HG + +F + Y + ID+D++ A +PKL Sbjct: 123 IMGMSLAAGGHLTHGAPP-----AQSGKWFNAVQYGVRLQDASIDFDEVATLAETHKPKL 177 Query: 744 IVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHK 923 I+AG SAY R+ D+ + R+I D+ A+ + DMAH +GLVAAG+ PSP YAD+VTTTTHK Sbjct: 178 IIAGGSAYPRIIDFAKFREIADRVGALFMVDMAHFAGLVAAGLHPSPLPYADIVTTTTHK 237 Query: 924 SLRGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQ 1103 +LRGPRG M+ D KIN+AVFPGLQGGP H I AVA + Sbjct: 238 TLRGPRGGMVLSNNP-------------DIGKKINSAVFPGLQGGPLMHIIAAKAVAFGE 284 Query: 1104 ATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLE 1283 A E++ Y + V+ N+ ++L + G +IVSGGTD HL LV+L+ K + G+ VEK LE Sbjct: 285 ALRPEFKVYAQAVIDNAKALTDALAAGGLNIVSGGTDTHLALVDLRPKALTGNIVEKSLE 344 Query: 1284 NVHIAANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXX 1460 +I NKN +P D + GIR+GTPA T+RGF +F ++ + Sbjct: 345 RANITTNKNGIPFDPEKPAITSGIRVGTPAGTTRGFGTAEFTEIGKLI------------ 392 Query: 1461 XXXGTKLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 ++ D +A + N QAE A +R V ++FP G Sbjct: 393 ----VEVLDGLAA-NGEDNSQAE-AAVREKVAVLCRRFPIYG 428
>Q9CHW7:GLYA_LACLA Serine hydroxymethyltransferase - Lactococcus lactis subsp. lactis| (Streptococcus lactis) Length = 415 Score = 329 bits (843), Expect = 3e-89 Identities = 183/398 (45%), Positives = 243/398 (61%), Gaps = 2/398 (0%) Frame = +3 Query: 231 EEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGN 410 E DPE+ I E+ RQ + +ELI SEN S +VM A GSV+TNKY+EGYPG RYYGG Sbjct: 9 ESFDPELWAAIHAEEIRQQQNIELIASENIVSKAVMAAQGSVLTNKYAEGYPGKRYYGGT 68 Query: 411 EYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHG 590 E +D+ E L +RA E F NVQP SGS AN Y AL++P D ++ +DL G Sbjct: 69 EAVDVVENLAIERAKELFGAK----FANVQPHSGSQANAAAYMALIQPGDTVLGMDLNAG 124 Query: 591 GHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYA 770 GHL+HG + S + F +PY ++ T L+DYD++ K A +PKLIVAGASAY+ Sbjct: 125 GHLTHGASVN---FSGKTYHF--VPYGVNSETELLDYDEILKIAKQVQPKLIVAGASAYS 179 Query: 771 RLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAM 950 RL D+ + R+I D A L+ DMAHI+GLVA G P+P YADVVTTTTHK+LRGPRG M Sbjct: 180 RLIDFAKFREIADSVGAKLMVDMAHIAGLVATGAHPNPLPYADVVTTTTHKTLRGPRGGM 239 Query: 951 IFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAY 1130 I KIN+A+FPG QGGP H I AVA K+A E+ Y Sbjct: 240 ILTNDEA-------------LAKKINSAIFPGTQGGPLEHVIAAKAVAFKEALDPEFTTY 286 Query: 1131 QEQVMSNSARFAESLTS-KGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 EQV+ N+ AE +G +++GG+DNHL+ + + GI+G + +L++VHI NK Sbjct: 287 IEQVIKNTQAMAEEFAKVEGLRLIAGGSDNHLLNLKVLDLGINGKEAQDLLDSVHITLNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 +P + +S G+R+G A+TSRGF E + KVA+ Sbjct: 347 EAIPDETLSPFKTSGVRIGAAAITSRGFKEVEAKKVAQ 384
>Q3II23:GLYA_PSEHT Serine hydroxymethyltransferase - Pseudoalteromonas haloplanktis| (strain TAC 125) Length = 418 Score = 328 bits (842), Expect = 4e-89 Identities = 180/397 (45%), Positives = 243/397 (61%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + DPE+ D I E ARQ +ELI SEN+ S V++A GS +TNKY+EGYPG RYYGG Sbjct: 8 ISDFDPELFDAIAKETARQEDHIELIASENYCSPRVLEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E L RA E F D NVQP +GS AN V+ ALL D ++ + L H Sbjct: 68 CEHVDVVEQLAIDRANELFGSDY----ANVQPHAGSQANAAVFLALLNAGDTVLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + Y LDE+TG IDY Q+E A+ +PK+I+ G SAY Sbjct: 124 GGHLTHG-----SHVNFSGKLYNAIQYGLDETTGEIDYAQVEALALEHKPKMIIGGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ ++R+I DK A DMAH++GL+AAG+ PSP +A VVTTTTHK+L GPRG Sbjct: 179 SGIVDWAKLREIADKIGAYFFVDMAHVAGLIAAGIYPSPVPHAHVVTTTTHKTLAGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I G + I K K+N+AVFPG QGGP H I AVA K+A E++ Sbjct: 239 LIISACGDEAIYK-----------KLNSAVFPGGQGGPLCHVIAAKAVAFKEALQPEFKV 287 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ QV+ N+ + +GY IVS T+NHL L++L K I G + L N HI NK Sbjct: 288 YQTQVVKNAQAMVAVMQERGYKIVSDKTENHLFLLDLINKDITGKDADAALGNAHITVNK 347 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D S V G+R+G+PA+T RGF E + ++A Sbjct: 348 NSVPNDPRSPFVTSGLRIGSPAITRRGFKEAESKELA 384
>Q9RYB2:GLYA_DEIRA Serine hydroxymethyltransferase - Deinococcus radiodurans| Length = 408 Score = 328 bits (842), Expect = 4e-89 Identities = 177/397 (44%), Positives = 250/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D + D+I E RQ GLELI SENFTS +V +A GSV+TNKY+EGYPG R+YGG E + Sbjct: 12 DDAVFDLIAQEAERQRTGLELIASENFTSAAVREAQGSVLTNKYAEGYPGKRWYGGCEVV 71 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D E L R + FN + W NVQP SGS AN VY AL++P D ++ +DL HGGHL Sbjct: 72 DQVEQLAIDRVKQLFNAE---WA-NVQPHSGSSANLAVYNALIQPGDTVLGMDLSHGGHL 127 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG K + + ++ + Y+LD T ID +++ + A +PK+I+AGASAY+R+ Sbjct: 128 THG-----NKANFSGMRYQMVAYQLDRETERIDMEEVRRLAHEHKPKMIIAGASAYSRVI 182 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ R+I D+ A+L AD+AHI+GL+AAG P+ +A VV +TTHK+LRGPRG +I Sbjct: 183 DFAAFREIADEVGALLFADIAHIAGLIAAGEHPNALPHAHVVASTTHKTLRGPRGGIILA 242 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 EI KQ ++ VFPG QGGP H I AVA +A E++ Y Q Sbjct: 243 ND--PEIAKQ-----------LDRTVFPGYQGGPLEHVIAAKAVAFGEALRPEFKDYARQ 289 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTVP 1319 ++ N+ A KGY +VSGGTDNHL L++L+ +G++G++ ++L+ HI +K+T+P Sbjct: 290 IIKNAQALAGEFQQKGYRVVSGGTDNHLFLLDLRPQGLNGTKATRLLDANHITISKSTLP 349 Query: 1320 GDVSAMV-PGGIRMGTPALTSRGFVEEDFAKVAEFFD 1427 D ++ GGIR+GTPA+T+RG E +VA+ D Sbjct: 350 YDTEKILHGGGIRIGTPAVTTRGMTEAHMTQVADLID 386
>Q7ND67:GLYA_GLOVI Serine hydroxymethyltransferase - Gloeobacter violaceus| Length = 426 Score = 328 bits (841), Expect = 5e-89 Identities = 181/398 (45%), Positives = 247/398 (62%), Gaps = 1/398 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L DP +A I+ E RQ LELI SENFTS +VM A GSV+TNKY+EG P RYYGG Sbjct: 8 LRATDPLVAGWIDRELNRQRSHLELIASENFTSAAVMAAQGSVLTNKYAEGLPSKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E + RA F NVQP SG+ AN V+ ALL+ D+I+ +DL H Sbjct: 68 CEFVDAVEQIAIDRAKALFGAAH----ANVQPHSGAQANAAVFLALLERGDKILGMDLSH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ I+FE + Y +D ++ ID+DQ+ + A RPKLI+ G SAY Sbjct: 124 GGHLTHG-----SPVNQSGIYFEALHYGVDPASHRIDFDQVRELAHAHRPKLIICGYSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ R+I D+ A LLAD+AHI+GLV AGV P+P + DVVTTTTHK+LRGPRG Sbjct: 179 PRVIDFECFREIADEVGAYLLADIAHIAGLVVAGVHPNPIPHCDVVTTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I R GK + + AVFPG QGGP H I AVA +A E++ Sbjct: 239 LILTRD-----EALGK--------RFDKAVFPGTQGGPLEHVIAAKAVAFGEALQPEFKT 285 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y V++N+ AE LT++G +VSGGTDNHL+LV+L+ + G + + ++ +V+I NK Sbjct: 286 YAADVVANARALAERLTARGLTLVSGGTDNHLMLVDLRSVDLTGKQADLLMSDVNITTNK 345 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 NT+P D S V G+R+G+PA+T+RG +F ++ E Sbjct: 346 NTIPFDPQSPFVTSGLRLGSPAMTTRGLGTTEFGEIGE 383
>Q5NFJ3:GLYA_FRATT Serine hydroxymethyltransferase - Francisella tularensis subsp.| tularensis Length = 417 Score = 328 bits (841), Expect = 5e-89 Identities = 178/397 (44%), Positives = 249/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ D EI D IELE RQ + +ELI SEN+ S +VM+A GS +TNKY+EGY G RYYGG Sbjct: 9 LKNTDKEIFDAIELEVKRQHEHVELIASENYASPAVMEAQGSQLTNKYAEGYHGKRYYGG 68 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+AE L +RA + F +D NVQP SGS AN VY A+LKP D ++ +DL Sbjct: 69 CEFVDIAEKLAIERAQQLFGVDY----ANVQPHSGSQANAAVYNAVLKPGDTVLGMDLGA 124 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K++ + ++ Y LDE+ G IDY Q+ + A +PK+I+AG SA+ Sbjct: 125 GGHLTHG-----SKVNFSGKIYNSIQYGLDEN-GDIDYKQVAQLAKEHKPKMIIAGFSAF 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + ++ + R+I D AVL+AD+AH++GLVAAGV P+PF Y V TTTTHK+LRGPRG Sbjct: 179 SGIINWQKFREIADSVDAVLMADIAHVAGLVAAGVYPNPFPYVYVATTTTHKTLRGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I + K +A+FPG+QGGP H I AVA K+A + Sbjct: 239 LILCNNNP------------ELAKKFQSAIFPGIQGGPLMHVIAAKAVAFKEALEPSFVD 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ + L +G +I+SGGT NHL+L+++ G G E L +I NK Sbjct: 287 YQKQVLKNAKAMEKVLKQRGINIISGGTSNHLLLLDITNTGFSGKEAEAALGRANITVNK 346 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N++P D S V G+R+G+PA+T+RGF E++ VA Sbjct: 347 NSIPNDPRSPFVTSGLRIGSPAITTRGFKEKECELVA 383
>P34894:GLYA_ACTAC Serine hydroxymethyltransferase - Actinobacillus| actinomycetemcomitans (Haemophilus actinomycetemcomitans) Length = 420 Score = 328 bits (841), Expect = 5e-89 Identities = 184/397 (46%), Positives = 237/397 (59%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + DP + IE E RQ + +ELI SEN+ S VMQA GS TNKY+EGYPG RYYGG Sbjct: 8 IADYDPVLWQAIENENRRQEEHIELIASENYASPRVMQAQGSQFTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY D+ E L +RA E F D VNVQP SGS AN VY LL P D I+ + L H Sbjct: 68 CEYADIVEQLAIERAKELFGADY----VNVQPHSGSQANAAVYMGLLNPGDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG +S + Y + + GLIDYD L K A +PK+IV G SAY Sbjct: 124 GGHLTHG-----ASVSFSGKIYHAEQYGITDE-GLIDYDALRKQAHDVKPKMIVGGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ +MR+I D+ A L DMAH++GLVAAG+ P+P YA VVTTTTHK+L GPRG Sbjct: 178 SQVVDWKKMREIADEVGAYLFVDMAHVAGLVAAGIYPNPLPYAHVVTTTTHKTLGGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I G +EI K K+N+AVFP QGGP H I AV K+A EY+ Sbjct: 238 LILSSCGDEEIYK-----------KLNSAVFPAGQGGPLVHIIAAKAVCFKEALEPEYKV 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+ V+ N+ E + Y +VS GT+NHL LV+L G+ G + L +I NK Sbjct: 287 YQQNVLKNAKAMVEVFKQRCYKVVSNGTENHLFLVDLVSHGLTGKAADAALGKANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N+VP D + GIR+GTP++T RGF E D ++A Sbjct: 347 NSVPNDPQKPFITSGIRVGTPSVTRRGFNEADVKELA 383
>Q5QXT4:GLYA_IDILO Serine hydroxymethyltransferase - Idiomarina loihiensis| Length = 418 Score = 328 bits (840), Expect = 7e-89 Identities = 188/454 (41%), Positives = 264/454 (58%), Gaps = 1/454 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + D ++ ++ E RQ + +ELI SEN+TS VMQA GS +TNKY+EGYP RYYGG Sbjct: 8 IADFDADLWQAMQDEVERQEQHIELIASENYTSPRVMQAQGSQLTNKYAEGYPHKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E L +RA E F NVQP SGS AN + A+++ D + + L H Sbjct: 68 CEFVDKVEDLAIERAKELFGAKY----ANVQPHSGSQANTAAFMAMMEAGDTFLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + Y LDESTG IDY ++EK A +PK+IVAG SAY Sbjct: 124 GGHLTHG-----SGVNFSGKLYNAVSYGLDESTGEIDYAEVEKLAQEHKPKVIVAGFSAY 178 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 + + D+ + R+I DK A L+ DMAH++GLVAAGV P+P YA VVTTTTHK+L GPRG Sbjct: 179 SGIVDWAKFREIADKVDAYLMVDMAHVAGLVAAGVYPNPVPYAHVVTTTTHKTLAGPRGG 238 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I ++++K K+N+AVFPG QGGP H I G AVA ++A E++ Sbjct: 239 LIISGSDDEKLHK-----------KLNSAVFPGNQGGPLCHVIAGKAVAFQEALQPEFKD 287 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ +++ ++GY IVS GT NHL LV+L K I G + L N I NK Sbjct: 288 YQKQVLVNANAMVKTMQARGYKIVSNGTQNHLFLVDLIDKDITGKDADAALGNAFITVNK 347 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N VP D S V G+R+GTPA+T RGF E + +VA Sbjct: 348 NAVPNDPRSPFVTSGLRLGTPAITRRGFKEAEAEQVA----------------------- 384 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIG 1586 +++ + D +++I ++R V+ +FP G Sbjct: 385 NWICDVLDDIADESKINQVREQVKALCAKFPVYG 418
>Q7NYI8:GLYA_CHRVO Serine hydroxymethyltransferase - Chromobacterium violaceum| Length = 415 Score = 328 bits (840), Expect = 7e-89 Identities = 179/397 (45%), Positives = 248/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + DPE+A I E RQ +ELI SEN+TS +VM+A GS +TNKY+EGYPG R+YGG Sbjct: 8 IAKFDPELAAAIAAECQRQEDHIELIASENYTSPAVMEAQGSQLTNKYAEGYPGKRFYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E L R + F + NVQP SGS AN VY ++LKP D +M ++L H Sbjct: 68 CEHVDVVEQLAIDRVKQLFGAEY----ANVQPHSGSQANQAVYFSILKPGDTVMGMNLGH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG + F + Y L++ IDYD +E+ A+ +PKLI+ GASAY Sbjct: 124 GGHLTHGSPANLS-----GKMFNIVAYGLNDKEE-IDYDDMERVAMETKPKLIIGGASAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 A +D+ RM +I K A + DMAH +GLVAAG+ P+P +AD VT+TTHK+LRGPRG Sbjct: 178 ALRFDFERMGQIAKKVGAYFMVDMAHYAGLVAAGLYPNPVPHADFVTSTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I K +FE IN+ VFP LQGGP H I AVA K+A ++ Sbjct: 238 IIL--------------AKAEFEKSINSNVFPTLQGGPLEHVIAAKAVAFKEALQPAFKE 283 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+A A++L +G IVSG T++H+ LV+L+ KG+ G + + +L HI NK Sbjct: 284 YQQQVLKNAAIMAKTLAERGLRIVSGRTESHVFLVDLRAKGLTGKQADALLGRAHITVNK 343 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N +P D + V GIR+G+PA+T+RGF E + +VA Sbjct: 344 NAIPNDPETPFVTSGIRIGSPAITTRGFKEAEAIEVA 380
>P57830:GLYA_PASMU Serine hydroxymethyltransferase - Pasteurella multocida| Length = 420 Score = 327 bits (839), Expect = 9e-89 Identities = 179/397 (45%), Positives = 245/397 (61%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 + + DP + I+ E RQ + +ELI SEN+ S VM+A GS TNKY+EGYPG RYYGG Sbjct: 8 IADYDPVLWQAIQDENRRQEEHIELIASENYASPRVMEAQGSQFTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY D+ E L RA E F+ D VNVQP SGS AN VY ALL+PHD I+ + L H Sbjct: 68 CEYADIVEQLAIDRAKELFHADY----VNVQPHSGSQANAAVYGALLQPHDTILGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG +S + + Y + + GLIDY+ + + A+ +PK+IVAG SAY Sbjct: 124 GGHLTHG-----ASVSFSGKIYNAVQYGIT-AEGLIDYEDVRQKALECKPKMIVAGFSAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +++ D+ +MR+I D+ A L DMAH++GL+AAGV PSP +A VVTTTTHK+L GPRG Sbjct: 178 SQVVDWAKMREIADEVGAYLFVDMAHVAGLIAAGVYPSPLPHAHVVTTTTHKTLGGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 +I +++ K K+ ++VFP QGGP H I AV K+A EY+ Sbjct: 238 LILSAAKDEDLYK-----------KLQSSVFPANQGGPLVHVIAAKAVCFKEALEPEYKV 286 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ+QV+ N+ + +GY++VS GT+NHL LV+L G+ G + L + +I NK Sbjct: 287 YQQQVVKNAKAMVDVFKQRGYNVVSNGTENHLFLVDLVSHGLTGKAADAALGSANITVNK 346 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N VP D V GIR+GTP++T RGF E + A++A Sbjct: 347 NAVPNDPQKPFVTSGIRVGTPSITRRGFKEAESAELA 383
>Q82UP9:GLYA_NITEU Serine hydroxymethyltransferase - Nitrosomonas europaea| Length = 416 Score = 327 bits (839), Expect = 9e-89 Identities = 183/400 (45%), Positives = 246/400 (61%), Gaps = 4/400 (1%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 +E+VDP++ I+ E RQ +ELI SEN+ S +V+QA G+V+TNKY+EGYPG RYYGG Sbjct: 8 IEQVDPDLWQAIKGEVQRQEDHIELIASENYASPAVLQAQGTVLTNKYAEGYPGKRYYGG 67 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 Y+D+ E L R FN + VNVQP SGS AN VY + LKP D ++ + L H Sbjct: 68 CRYVDIVEQLAIDRLRNLFNAEY----VNVQPHSGSQANAAVYLSALKPGDTLLGMSLAH 123 Query: 588 GGHLSHGYQTDTKKISAVSI---FFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 GGHL+HG SAV++ F ++ Y L+ T IDY +LE+ A +P++IVAGA Sbjct: 124 GGHLTHG--------SAVNMSGKIFNSISYGLNPETEEIDYAELERLAHEHKPRMIVAGA 175 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 S+YAR+ D+ R+I D A L DMAH +GL+AAG P+P AD VT+TTHK+LRGP Sbjct: 176 SSYARVIDWKAFRQIADNVGAYLFVDMAHYAGLIAAGYYPNPVGIADFVTSTTHKTLRGP 235 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I K + E +N+AVFP QGGP H I AVA K+A++Q Sbjct: 236 RGGVIM--------------AKPEHEKALNSAVFPQTQGGPLMHVIAAKAVAFKEASSQA 281 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ YQ+QV+ N+ A L +G IVSG TD H+ LV+L+ K + G E LE HI Sbjct: 282 FKDYQKQVIENARVMARVLQQRGLRIVSGRTDCHMFLVDLRAKNLTGREAESALEAAHIT 341 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 NKN +P D V GIR+GTPA+T+RGF E + ++A Sbjct: 342 VNKNAIPNDPQKPFVTSGIRIGTPAITTRGFKEPESEELA 381
>Q2JT50:GLYA_SYNJA Serine hydroxymethyltransferase - Synechococcus sp. (strain JA-3-3Ab)| (Cyanobacteria bacterium Yellowstone A-Prime) Length = 434 Score = 327 bits (838), Expect = 1e-88 Identities = 190/420 (45%), Positives = 252/420 (60%), Gaps = 13/420 (3%) Frame = +3 Query: 198 VTWPKQLNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSE 377 +T P+ A L E DP + +I+ E RQ LE+I SENFTS +V+ A GSV+TNKY+E Sbjct: 1 MTTPRDNLAILAETDPVVYRLIQQELNRQRDHLEMIASENFTSPAVLAAQGSVLTNKYAE 60 Query: 378 GYPGARYYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPH 557 G PG RYYGG E+ID E L RA + F NVQP SG+ ANF V+ ALL+P Sbjct: 61 GLPGKRYYGGCEFIDEIEQLAIDRAKQLFGAAH----ANVQPHSGAQANFAVFLALLQPG 116 Query: 558 DRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRP 737 D IM +DL HGGHL+HG ++ +F + Y +D T ID+DQ+ A RP Sbjct: 117 DTIMGMDLAHGGHLTHG-----SPVNVSGKWFRVVHYGVDPQTERIDFDQVRDLARQHRP 171 Query: 738 KLIVAGASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTT 917 KLI+ G SAY R+ D+ R I D+ A L+AD+AHI+GLVA G P+P DVVTTTT Sbjct: 172 KLIICGYSAYPRIIDFAAFRAIADEVGAYLMADIAHIAGLVATGHHPNPVPICDVVTTTT 231 Query: 918 HKSLRGPRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVAL 1097 HK+LRGPRG +I R E+ K K++ AVFPG QGGP H I G AVA Sbjct: 232 HKTLRGPRGGLILTRD--PELGK-----------KLDKAVFPGSQGGPLEHVIAGKAVAF 278 Query: 1098 KQATTQEYRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLK-------KKG-- 1250 +A + Y QV++N+ A +L +G +VSGGTDNHLVL++L+ K G Sbjct: 279 GEALQPSFAQYSAQVIANAQALAATLQRRGIRLVSGGTDNHLVLLDLRSVSAVLEKNGAA 338 Query: 1251 ---IDGSRVEKVLENVHIAANKNTVPGDVS-AMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 + G R ++++E +HI ANKNT+P D V G+R+G+PALT+RG +F ++ E Sbjct: 339 DPVMTGKRADRLMEEIHITANKNTIPFDPQPPSVASGLRLGSPALTTRGLGPAEFEEIGE 398
>Q6G009:GLYA_BARQU Serine hydroxymethyltransferase - Bartonella quintana (Rochalimaea| quintana) Length = 437 Score = 327 bits (837), Expect = 1e-88 Identities = 188/458 (41%), Positives = 261/458 (56%), Gaps = 1/458 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N L+ VD I D I E RQ +ELI SEN S +V++A GS++TNKY+EGYP R+ Sbjct: 14 NDNLQTVDVAIFDAINGEFKRQQHEIELIASENIVSRAVLEAQGSILTNKYAEGYPRKRF 73 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG ++D+ E L +RA + F NVQ SGS N V+ ALL+P D M LD Sbjct: 74 YGGCRFVDVVEDLAIERAKQLFGAA----FANVQAHSGSQMNQAVFLALLQPGDTFMGLD 129 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG ++ +F+ + Y + + ++D +++E+ A +PKLI+ G Sbjct: 130 LNSGGHLTHG-----SSVNMSGKWFDVVSYGVRKEDQILDMEEIERLAKEHKPKLIITGG 184 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY+RL+D+ R R+I D+ A LL DM+HI+GLVA GV PSP +A +VTTTTHKSLRGP Sbjct: 185 SAYSRLWDWKRFREIADEIGAYLLVDMSHIAGLVAGGVHPSPVPHAHIVTTTTHKSLRGP 244 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I KIN+A+FPGLQGGP H I AVA ++A Sbjct: 245 RGGLILTNDET-------------LARKINSAIFPGLQGGPLMHVIAAKAVAFEEALQPA 291 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y V+ N+ A++L S G+DIVSGGTDNHL+LV+L K + G R E L HI Sbjct: 292 FKNYSANVVVNAKTLAKTLQSNGFDIVSGGTDNHLLLVDLCSKKVTGKRAELALGRAHIT 351 Query: 1299 ANKNTVPGDVSA-MVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGT 1475 NKN +P D+ A V GIR+G+PA T+RG E +F +V + Sbjct: 352 CNKNAIPFDLQAPSVTSGIRLGSPAATTRGLAENEFVQVGHMI----------------S 395 Query: 1476 KLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFPTIGF 1589 ++ D + +SD + A +R VE+ +FP + Sbjct: 396 EVLDGLQMAKSDEDNNAVEMAVRKKVEDMTNKFPLYSY 433
>Q81JY4:GLYA_BACAN Serine hydroxymethyltransferase - Bacillus anthracis| Length = 413 Score = 327 bits (837), Expect = 1e-88 Identities = 175/397 (44%), Positives = 247/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ D ++ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 4 LKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E + + R E F + VNVQP SG+ AN VY +L+ D ++ ++L H Sbjct: 64 CEHVDVVEDIARDRVKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + + Y +D + I+YD + A +PKLIVAGASAY Sbjct: 120 GGHLTHG-----SPVNFSGVQYNFVEYGVDAESHCINYDDVLAKAKEHKPKLIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ R R+I D+ A L+ DMAHI+GLVAAG+ P+P +A VTTTTHK+LRGPRG Sbjct: 175 PRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI + F +I+ ++FPG+QGGP H I AVA +A +++ Sbjct: 235 MILCEE--------------QFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKT 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y + +++N+ R AE L +G +VSGGTDNHL+L++++ I G E VL+ V I NK Sbjct: 281 YAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNK 340 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 NT+P + S V G+R+GT A+TSRGF ED ++A Sbjct: 341 NTIPFETASPFVTSGVRIGTAAVTSRGFGLEDMDEIA 377
>P50435:GLYA_METEX Serine hydroxymethyltransferase - Methylobacterium extorquens| (Protomonas extorquens) Length = 434 Score = 326 bits (836), Expect = 2e-88 Identities = 182/399 (45%), Positives = 237/399 (59%), Gaps = 1/399 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 +A L E DPEIA I E RQ +ELI SEN S +V++A GSV+TNKY+EGYPG RY Sbjct: 17 SAHLAETDPEIAKAISQELGRQQHEIELIASENIVSRAVLEAQGSVLTNKYAEGYPGRRY 76 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG +++D+AE L RA F NVQP SGS AN V+ AL++P D + LD Sbjct: 77 YGGCQFVDIAEELAIDRAKRLFGCG----FANVQPNSGSQANQGVFMALMQPGDTFLGLD 132 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG + +F+ + Y + ID +Q+E+ A +PK+I+AG Sbjct: 133 LAAGGHLTHGAPPNVS-----GKWFKPVSYTVRREDQRIDMEQVERLAQEHKPKVIIAGG 187 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 S Y R +D+ + R+I D A DMAH +GLVAAG+ PSPF +A V TTTTHK+LRGP Sbjct: 188 SGYPRHWDFAKFREIADSVGAYFFVDMAHFAGLVAAGLHPSPFPHAHVATTTTHKTLRGP 247 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG MI K N+A+FPGLQGGP H I A A +A E Sbjct: 248 RGGMILTNDEA-------------LAKKFNSAIFPGLQGGPLMHVIAAKAAAFGEALKPE 294 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 ++ Y +QV+ N+ A+++ S GYDI SGGTDNHL+LV+L+KKG+ G E L I Sbjct: 295 FKIYAKQVIDNARALADTIISGGYDITSGGTDNHLMLVDLQKKGLTGKAAEAALSRADIT 354 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKV 1412 NKN VP D + GIR+GTPA T+RGF +F +V Sbjct: 355 CNKNGVPFDPQKPTITSGIRLGTPASTTRGFGVAEFKQV 393
>Q6HAW9:GLYA_BACHK Serine hydroxymethyltransferase - Bacillus thuringiensis subsp.| konkukian Length = 414 Score = 326 bits (836), Expect = 2e-88 Identities = 175/397 (44%), Positives = 247/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ D ++ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 5 LKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 64 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E + + R E F + VNVQP SG+ AN VY +L+ D ++ ++L H Sbjct: 65 CEHVDVVEDIARDRVKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSH 120 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + + Y +D + I+YD + A +PKLIVAGASAY Sbjct: 121 GGHLTHG-----SPVNFSGVQYNFVEYGVDAESHRINYDDVLAKAKEHKPKLIVAGASAY 175 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ R R+I D+ A L+ DMAHI+GLVAAG+ P+P +A VTTTTHK+LRGPRG Sbjct: 176 PRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGG 235 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI + F +I+ ++FPG+QGGP H I AVA +A +++ Sbjct: 236 MILCEE--------------QFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKT 281 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y + +++N+ R AE L +G +VSGGTDNHL+L++++ I G E VL+ V I NK Sbjct: 282 YAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNK 341 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 NT+P + S V G+R+GT A+TSRGF ED ++A Sbjct: 342 NTIPFETASPFVTSGVRIGTAAVTSRGFGLEDMDEIA 378
>Q6KHH3:GLYA_MYCMO Serine hydroxymethyltransferase - Mycoplasma mobile| Length = 418 Score = 326 bits (835), Expect = 2e-88 Identities = 186/449 (41%), Positives = 266/449 (59%), Gaps = 2/449 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D EI II E+ RQ + +ELI SEN+ S V++A GS++TNKYSEGYPGARYY G E++ Sbjct: 8 DKEIEKIINNEQQRQEEHIELIASENYVSKDVLEATGSILTNKYSEGYPGARYYDGCEFV 67 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D ETL +R + FN+ NVQP SGS AN AL+KP +I+ + L GGHL Sbjct: 68 DQIETLAIERLKKLFNVK----FANVQPHSGSSANSAAIAALVKPGGKILGMSLDAGGHL 123 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HGY KIS F++ Y +++ GL+DYD +EK A +P+LI+ GAS Y+R Sbjct: 124 THGY-----KISFSGTFYDPYFYGVNDE-GLLDYDVIEKLAEKIKPELIICGASNYSRTI 177 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + KI K A LLAD+AHI+GL+ A + PSP +ADV+T+TTHK++RG RG +I Sbjct: 178 DFEKFSKIAKKVGAFLLADIAHIAGLIIADLHPSPVGHADVITSTTHKTIRGARGGIIMS 237 Query: 960 RKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQEQ 1139 KI+ VFPG QGGP H I G AVA +A T +++ YQ+Q Sbjct: 238 NDET-------------LMKKIDRWVFPGYQGGPLVHVIAGKAVAFGEALTPQFKKYQQQ 284 Query: 1140 VMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKK-GIDGSRVEKVLENVHIAANKNTV 1316 ++SN+ F+E G I+SG TDNHL +++K I G +++ +++I ANKN++ Sbjct: 285 IISNAKAFSEEFKKVGTKIISGQTDNHLFTIDVKSSFNISGKEASELMHSINITANKNSI 344 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLKDFV 1493 P D + + G+RMGTPA+T+RGF E +F K+A + + + Sbjct: 345 PNDTLGPKISSGVRMGTPAMTTRGFKEVEFKKLARI-------------------IIELL 385 Query: 1494 ATLQSDSNIQAEIAKLRHDVEEYAKQFPT 1580 A + SN+++ KL+++V E K FPT Sbjct: 386 AN-STSSNLESLKLKLKNEVLELTKAFPT 413
>Q47XG4:GLYA3_COLP3 Serine hydroxymethyltransferase 3 - Colwellia psychrerythraea (strain| 34H / ATCC BAA-681) (Vibrio psychroerythus) Length = 431 Score = 326 bits (835), Expect = 2e-88 Identities = 185/402 (46%), Positives = 248/402 (61%), Gaps = 1/402 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 ++ L D + I+LE+ARQ + +ELI SEN S +VM+A G+V+TNKY+EGYPG RY Sbjct: 15 SSDLSSTDGAVQVAIDLEEARQNQQIELIASENIVSKAVMEAQGTVLTNKYAEGYPGRRY 74 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG E++D+ ETL RA F D VNVQP SG+ AN V AL+KP D I+ + Sbjct: 75 YGGCEHVDLVETLAIDRAKLIFKAD----FVNVQPHSGAQANGAVMLALVKPGDTILGMS 130 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG K + +F + Y + + IDYDQ+ A+ +PK+I+AG Sbjct: 131 LDAGGHLTHG-----AKPAQSGKWFNAIHYGVRKDDMRIDYDQVLALAIEHQPKMIIAGG 185 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SA R D+ + R+I D+ A+L+ DMAHI+GLVAAG +P +ADVVTTTTHK+LRGP Sbjct: 186 SAIPRQIDFAKFREIADQVGAILMVDMAHIAGLVAAGAHQNPLPFADVVTTTTHKTLRGP 245 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I D KIN+AVFPGLQGGP H I AVAL + Sbjct: 246 RGGLILTNNP-------------DVAKKINSAVFPGLQGGPLMHVIAAKAVALGEVLEPS 292 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 + AY +QV+SN+ A +L +G DIV+ GTD HL+LV+L+ KG+ G+ E+ LE I Sbjct: 293 FGAYIKQVLSNARVLASTLQQRGCDIVTDGTDTHLMLVDLRPKGLKGNTTEESLERAGIT 352 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 NKN +P D MV GIR+GTPA TSRGF ++F + ++ Sbjct: 353 CNKNGIPFDSEKPMVTSGIRLGTPAGTSRGFGNDEFELIGQW 394
>Q9KMP4:GLYA2_VIBCH Serine hydroxymethyltransferase 2 - Vibrio cholerae| Length = 435 Score = 326 bits (835), Expect = 2e-88 Identities = 193/454 (42%), Positives = 265/454 (58%), Gaps = 1/454 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 + PL + + I+ E RQ + +ELI SEN S +VMQA G+ +TNKY+EGYPG RY Sbjct: 19 STPLAATNDAVFAAIQAEYTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRY 78 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG E++D E + +RA F NVQP SG+ AN V ALL+P D IM + Sbjct: 79 YGGCEHVDSVEQIAIERAKMLFQCQY----ANVQPHSGAQANGAVMLALLQPGDTIMGMS 134 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L GGHL+HG + + +F + Y +D T I+YD + A+ +PK+I+AG Sbjct: 135 LDAGGHLTHGARP-----ALSGKWFNAVQYGVDRQTLEINYDSVRALALEHKPKMIIAGG 189 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SA R D+ + R I D+ A+L+ DMAHI+GLVA G PSP +A VVTTTTHK+LRGP Sbjct: 190 SAIPRTIDFAQFRSIVDEVGALLMVDMAHIAGLVATGAHPSPLPHAHVVTTTTHKTLRGP 249 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG MI +EI+K KIN+AVFPGLQGGP H I AVA +A E Sbjct: 250 RGGMILTNS--EEIHK-----------KINSAVFPGLQGGPLMHVIAAKAVAFGEALGPE 296 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 +R Y + V+ N+ AE L ++G DIV+GGTD HL+LV+L+ KG+ G++VE+ LE I Sbjct: 297 FRTYIDSVIDNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNQVEQALERAGIT 356 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGT 1475 NKN +P D M+ GIR+GTPA TSRGF E+F + E+ G Sbjct: 357 CNKNGIPFDEEKPMITSGIRLGTPAGTSRGFGREEFKLIGEWI---------------GD 401 Query: 1476 KLKDFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 L VA+ + + +++ ++ R V+ ++FP Sbjct: 402 VLDGLVASPEGNPDVEQQV---RKQVKALCQRFP 432
>Q30R29:GLYA1_THIDN Serine hydroxymethyltransferase 1 - Thiomicrospira denitrificans| (strain ATCC 33889 / DSM 1351) Length = 415 Score = 326 bits (835), Expect = 2e-88 Identities = 186/397 (46%), Positives = 240/397 (60%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+E D +I D+ E E RQ LE+I SENFT +VM+A+GSV TNKY+EGYP RYYGG Sbjct: 4 LKEFDKDIFDLCEKELERQSNHLEMIASENFTLPAVMEAMGSVFTNKYAEGYPAKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 EY D E L RA + F + NVQP SGS AN VY ALLK D+++ +DL H Sbjct: 64 CEYADGVEQLAIDRACKLFGCNY----ANVQPHSGSQANAAVYAALLKAGDKLLGMDLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG K S + + Y + E G ++YD++ + A +PK+IV GASAY Sbjct: 120 GGHLTHG-----SKPSFSGQNYSSFTYGV-ELDGRMNYDKILEIAKAVQPKIIVCGASAY 173 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 AR D+ + R+I D A++ AD+AH++GLV AG SPF +A VVTTTTHK+L GPRG Sbjct: 174 AREIDFKKFREIADAVGAIMFADIAHVAGLVVAGEHMSPFPHAHVVTTTTHKTLAGPRGG 233 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI D KIN+A+FPG+QGGP H I AV K + E++ Sbjct: 234 MIMTNDE-------------DIAKKINSAIFPGIQGGPLVHVIAAKAVGFKYNLSAEWKD 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y QV +N+ E L +GYD+VSGGTDNHLVL++ + G + L N I NK Sbjct: 281 YAVQVKANAKILGEVLVKRGYDLVSGGTDNHLVLLSFLNRDFSGKDADIALGNAGITVNK 340 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 NTVPG+ S V GIR+G+PALTSRG E +F +A Sbjct: 341 NTVPGETRSPFVTSGIRIGSPALTSRGMKEREFEFIA 377
>O86565:GLYA_STRCO Serine hydroxymethyltransferase - Streptomyces coelicolor| Length = 420 Score = 325 bits (832), Expect = 6e-88 Identities = 184/407 (45%), Positives = 248/407 (60%), Gaps = 6/407 (1%) Frame = +3 Query: 216 LNAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 395 LN PL E+DP++A ++ E RQ LE+I SENF ++VM+A GSV+TNKY+EGYPG R Sbjct: 4 LNTPLHELDPDVAAAVDAELDRQQSTLEMIASENFAPVAVMEAQGSVLTNKYAEGYPGRR 63 Query: 396 YYGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMAL 575 YYGG E++D+ E + R F + NVQP SG+ AN ALLKP D IM L Sbjct: 64 YYGGCEHVDVVEQIAIDRVKALFGAEH----ANVQPHSGAQANAAAMFALLKPGDTIMGL 119 Query: 576 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAG 755 +L HGGHL+HG KI+ + +PY + + G +D ++E+ A +PKLIVAG Sbjct: 120 NLAHGGHLTHGM-----KINFSGKLYNVVPYHVGDD-GQVDMAEVERLAKETKPKLIVAG 173 Query: 756 ASAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRG 935 SAY R D+ RK+ D+ A L+ DMAH +GLVAAG+ P+P +A VVTTTTHK+L G Sbjct: 174 WSAYPRQLDFAAFRKVADEVGAYLMVDMAHFAGLVAAGLHPNPVPHAHVVTTTTHKTLGG 233 Query: 936 PRGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQ 1115 PRG +I E+ K KIN+AVFPG QGGP H + AVA K A ++ Sbjct: 234 PRGGVIL---STAELAK-----------KINSAVFPGQQGGPLEHVVAAKAVAFKVAASE 279 Query: 1116 EYRAYQEQVMSNSARFAESLT-----SKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVL 1280 +++ Q + + + AE L + G +++GGTD HLVLV+L+ +DG + E L Sbjct: 280 DFKERQGRTLEGARILAERLVRDDAKAAGVSVLTGGTDVHLVLVDLRDSELDGQQAEDRL 339 Query: 1281 ENVHIAANKNTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAE 1418 V I N+N VP D MV G+R+GTPAL +RGF EDFA+VA+ Sbjct: 340 HEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFTAEDFAEVAD 386
>Q630T3:GLYA_BACCZ Serine hydroxymethyltransferase - Bacillus cereus (strain ZK / E33L)| Length = 414 Score = 325 bits (832), Expect = 6e-88 Identities = 174/397 (43%), Positives = 247/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ D ++ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 5 LKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 64 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E + + R E F + VNVQP SG+ AN VY +L+ D ++ ++L H Sbjct: 65 CEHVDVVEDIARDRVKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSH 120 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + + Y +D + I+YD + A +PKLIVAGASAY Sbjct: 121 GGHLTHG-----SPVNFSGVQYNFVEYGVDAESHRINYDDVLAKAKEHKPKLIVAGASAY 175 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ R R+I D+ A L+ DMAHI+GLVAAG+ P+P +A VTTTTHK+LRGPRG Sbjct: 176 PRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGG 235 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI + F +I+ ++FPG+QGGP H I AVA +A +++ Sbjct: 236 MILCEE--------------QFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKT 281 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y + +++N+ R AE L +G +VSGGTDNHL+L++++ I G E VL+ V I NK Sbjct: 282 YAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNK 341 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 NT+P + S V G+R+GT A+TSRGF E+ ++A Sbjct: 342 NTIPFETASPFVTSGVRIGTAAVTSRGFGLEEMDEIA 378
>Q814V2:GLYA_BACCR Serine hydroxymethyltransferase - Bacillus cereus (strain ATCC 14579| / DSM 31) Length = 414 Score = 325 bits (832), Expect = 6e-88 Identities = 174/397 (43%), Positives = 247/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ D ++ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 5 LKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 64 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E + + R E F + VNVQP SG+ AN VY +L+ D ++ ++L H Sbjct: 65 CEHVDVVEDIARDRVKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSH 120 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + + Y +D + I+YD + A +PKLIVAGASAY Sbjct: 121 GGHLTHG-----SPVNFSGVQYNFVEYGVDADSHRINYDDVLAKAKEHKPKLIVAGASAY 175 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ R R+I D+ A L+ DMAHI+GLVAAG+ P+P +A VTTTTHK+LRGPRG Sbjct: 176 PRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGG 235 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI + F +I+ ++FPG+QGGP H I AVA +A +++ Sbjct: 236 MILCEE--------------QFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKT 281 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y + +++N+ R AE L +G +VSGGTDNHL+L++++ I G E VL+ V I NK Sbjct: 282 YAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNK 341 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 NT+P + S V G+R+GT A+TSRGF E+ ++A Sbjct: 342 NTIPFETASPFVTSGVRIGTAAVTSRGFGLEEMDEIA 378
>Q72XD7:GLYA_BACC1 Serine hydroxymethyltransferase - Bacillus cereus (strain ATCC 10987)| Length = 413 Score = 325 bits (832), Expect = 6e-88 Identities = 174/397 (43%), Positives = 247/397 (62%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L+ D ++ IE E RQ +ELI SENF S +VM+A GSV+TNKY+EGYPG RYYGG Sbjct: 4 LKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 63 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D+ E + + R E F + VNVQP SG+ AN VY +L+ D ++ ++L H Sbjct: 64 CEHVDVVEDIARDRVKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSH 119 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ + + + Y +D + I+YD + A +PKLIVAGASAY Sbjct: 120 GGHLTHG-----SPVNFSGVQYNFVEYGVDAESHRINYDDVLAKAKEHKPKLIVAGASAY 174 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ R R+I D+ A L+ DMAHI+GLVAAG+ P+P +A VTTTTHK+LRGPRG Sbjct: 175 PRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGG 234 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI + F +I+ ++FPG+QGGP H I AVA +A +++ Sbjct: 235 MILCEE--------------QFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKT 280 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y + +++N+ R AE L +G +VSGGTDNHL+L++++ I G E VL+ V I NK Sbjct: 281 YAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNK 340 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 NT+P + S V G+R+GT A+TSRGF E+ ++A Sbjct: 341 NTIPFETASPFVTSGVRIGTAAVTSRGFGLEEMDEIA 377
>Q6LHN7:GLYA2_PHOPR Serine hydroxymethyltransferase 2 - Photobacterium profundum| (Photobacterium sp. (strain SS9)) Length = 431 Score = 324 bits (831), Expect = 7e-88 Identities = 189/451 (41%), Positives = 269/451 (59%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L +VD + IE E RQ + +ELI SEN S +VMQA G+ +TNKY+EGY G RYYGG Sbjct: 18 LAQVDGAVNAGIEAELNRQNQQIELIASENIVSKAVMQAQGTCLTNKYAEGYAGHRYYGG 77 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E + RA + F + VNVQP SG+ AN V ALL+P D I+ + L Sbjct: 78 CEHVDEVEKIAIARAKQLFQCEY----VNVQPHSGAQANGAVMLALLQPGDTILGMSLDA 133 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG + + +F+ + Y +++ T IDY+Q+ + A+ +PK+I+AG SA Sbjct: 134 GGHLTHGARP-----ALSGKWFDAVQYGVNKDTLEIDYNQVRELAIEHKPKMIIAGGSAI 188 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ ++ + R+I D+ A L+ DMAHI+GL+AAG PSP +A V+TTTTHK+LRGPRG Sbjct: 189 PRIINFAKFREIADEVGAFLMVDMAHIAGLIAAGEHPSPIPHAHVITTTTHKTLRGPRGG 248 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI +++INK KIN+AVFPGLQGGP H I G AVA +A +++ Sbjct: 249 MIL--TNLEDINK-----------KINSAVFPGLQGGPLMHVIAGKAVAFGEALEPDFKI 295 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y + V+SN+ AE L ++G DIV+ GTD HL+LV+L+ KG+ G+ E LE I NK Sbjct: 296 YIKNVISNAKVLAEVLQNRGCDIVTNGTDTHLMLVDLRPKGLKGNAAENALERAGITCNK 355 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D MV GIR+GTPA TSRGF ++F ++ E+ G L Sbjct: 356 NGIPFDTEKPMVTSGIRLGTPAGTSRGFGNDEFKQIGEWI---------------GDVLD 400 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 A + +S ++ + + V++ +FP Sbjct: 401 GLAANPEDNSEVEKHV---KQQVQKLCSRFP 428
>Q660S1:GLYA_BORGA Serine hydroxymethyltransferase - Borrelia garinii| Length = 417 Score = 324 bits (830), Expect = 9e-88 Identities = 183/396 (46%), Positives = 245/396 (61%), Gaps = 2/396 (0%) Frame = +3 Query: 240 DPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYI 419 D +I ++IE EK R+ + ++LI SENFTSL + QAVGS++TNKY+EGYP RYYGG ++ Sbjct: 3 DDQIFNLIEKEKLREKEHIKLIASENFTSLEIRQAVGSILTNKYAEGYPLNRYYGGCSFV 62 Query: 420 DMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHL 599 D E+L RA E F NVQP SGS AN AL+ P DRI+ + L HGGHL Sbjct: 63 DEIESLAILRAKELFGAKY----ANVQPHSGSQANMAAIMALINPGDRILGMQLSHGGHL 118 Query: 600 SHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAYARLY 779 +HG +++ IFF T Y + + LIDYD++ K A RP LI+AGAS+Y+R Sbjct: 119 THG-----SRVNFSGIFFNTYFYGVSRDSELIDYDEVLKIARDCRPNLIIAGASSYSREI 173 Query: 780 DYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFF 959 D+ + R+I D A LL D+AHI+GL+ AG S + A + T+TTHK+LRGPRG +I Sbjct: 174 DFKKFREIADDVSAYLLCDIAHIAGLIVAGFHNSSIDVAHLTTSTTHKTLRGPRGGIILS 233 Query: 960 RKGV-KEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRAYQE 1136 K K + GKE + +N+ VFPG QGGP H I G A+A ++A + +R Y Sbjct: 234 GKDFDKLVTFNGKEKA--LFNAVNSTVFPGTQGGPLVHVIAGKAIAFREALQESFREYIA 291 Query: 1137 QVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANKNTV 1316 V+ N+ AE S+G+ IVSGGTDNHL LV+L + G+ EK+LE V+I NKN + Sbjct: 292 NVIKNTKVMAEYFKSEGFRIVSGGTDNHLFLVDLSNLDLTGADAEKLLEGVNITLNKNAI 351 Query: 1317 PGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 P D S + GIR+G A+TSRG E D VA+F Sbjct: 352 PFDKKSPSLASGIRIGGAAITSRGLNENDSLNVAKF 387
>Q7MEH7:GLYA2_VIBVY Serine hydroxymethyltransferase 2 - Vibrio vulnificus (strain YJ016)| Length = 431 Score = 324 bits (830), Expect = 9e-88 Identities = 182/399 (45%), Positives = 248/399 (62%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L D + I+ E RQ + +ELI SEN S +VMQA G+ +TNKY+EGYPG RYYGG Sbjct: 18 LSATDDAVFAGIQAEFTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGG 77 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E + +RA + FN + NVQP SG+ AN V ALL+P D IM + L Sbjct: 78 CEHVDTVEAIAIERAKKLFNCEY----ANVQPHSGAQANGAVKLALLQPGDTIMGMSLDA 133 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG + + +F + Y +D+ T I+YD + AV +PK+I+AG SA Sbjct: 134 GGHLTHGARP-----ALSGKWFNAVQYGVDKETLEINYDDVRALAVEHKPKMIIAGGSAI 188 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ + R+I D+ A+L+ DMAHI+GL+A G PSP +A VVTTTTHK+LRGPRG Sbjct: 189 PRVIDFAKFREIADEVGAILMVDMAHIAGLIATGAHPSPLPHAHVVTTTTHKTLRGPRGG 248 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI +EI K KIN+AVFPGLQGGP H I AVA +A E++ Sbjct: 249 MILTNH--EEIIK-----------KINSAVFPGLQGGPLMHVIAAKAVAFGEALGPEFKT 295 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y + V++N+ AE L ++G DIV+GGTD HL+LV+L+ KG+ G++ E+ LE I NK Sbjct: 296 YIDSVINNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNKAEEALERAGITCNK 355 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 N +P D M+ G+R+GTPA TSRGF E+F + + Sbjct: 356 NGIPFDTEKPMITSGVRLGTPAGTSRGFGAEEFKLIGHW 394
>P43844:GLYA_HAEIN Serine hydroxymethyltransferase - Haemophilus influenzae| Length = 421 Score = 323 bits (829), Expect = 1e-87 Identities = 181/400 (45%), Positives = 242/400 (60%), Gaps = 1/400 (0%) Frame = +3 Query: 219 NAPLEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 398 N + + DP + I+ E RQ + +ELI SEN+ S VM+A GS TNKY+EGYPG RY Sbjct: 5 NMTIADYDPVLWQAIQDENRRQEEHIELIASENYASPRVMEAQGSQFTNKYAEGYPGKRY 64 Query: 399 YGGNEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALD 578 YGG EY D+ E L RA E F D VNVQP SGS AN VY AL+ D I+ +D Sbjct: 65 YGGCEYADIVEQLAIDRAKELFGADY----VNVQPHSGSQANAAVYGALINAGDTILGMD 120 Query: 579 LPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGA 758 L HGGHL+HG K+S + ++ Y + + GLIDY+ + + A+ +PKLIVAG Sbjct: 121 LAHGGHLTHG-----AKVSFSGKIYNSVLYGIT-ADGLIDYEDVRQKALECKPKLIVAGF 174 Query: 759 SAYARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGP 938 SAY+++ D+ +MR+I D+ A L DMAH++GL+AAG+ P+P +A VVTTTTHK+L GP Sbjct: 175 SAYSQVVDWAKMREIADEVGAYLFVDMAHVAGLIAAGLYPNPLPHAHVVTTTTHKTLGGP 234 Query: 939 RGAMIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQE 1118 RG +I G +EI K K+ ++VFP QGGP H I AV K A + Sbjct: 235 RGGLILSSCGDEEIYK-----------KLQSSVFPANQGGPLVHIIAAKAVCFKGALEPQ 283 Query: 1119 YRAYQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIA 1298 Y+ YQ V+ N+ E +GYD+VS GT+NHL LV+ K+G+ G + L +I Sbjct: 284 YKEYQANVIKNAKAMVEVFKQRGYDVVSNGTENHLFLVSFIKQGLTGKAADAALGKANIT 343 Query: 1299 ANKNTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 NKN VP D V GIR+GTP++T RGF E D ++A Sbjct: 344 VNKNAVPNDPQKPFVTSGIRVGTPSVTRRGFNENDVRELA 383
>Q2ILI1:GLYA_ANADE Serine hydroxymethyltransferase - Anaeromyxobacter dehalogenans| (strain 2CP-C) Length = 417 Score = 323 bits (829), Expect = 1e-87 Identities = 176/397 (44%), Positives = 242/397 (60%), Gaps = 1/397 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L E DP+IA +I E RQ +GLELI SENF S +V++A+GS +TNKY+EGYPG RYYGG Sbjct: 7 LAEADPQIAKLIREETRRQAEGLELIASENFVSPAVLEALGSTLTNKYAEGYPGKRYYGG 66 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E +D E L RA + F D NVQP +GS AN Y AL KP D ++A+ L Sbjct: 67 CEVVDQVEQLAIDRAKQLFGADH----ANVQPHAGSQANMAAYFALAKPGDTVLAMSLNF 122 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG ++ F+ +PY L +S ID D++ + A RP++++ GASAY Sbjct: 123 GGHLTHG-----SPVNFSGKLFKIVPYGLRQSDETIDMDEVARLAREHRPRILMVGASAY 177 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 +R ++R +I ++ A ++ DMAHI+GLVAAG+ PSP ++++VTTTTHK+LRGPRG Sbjct: 178 SRTLHFDRFAEIANEVGAAMVVDMAHIAGLVAAGLHPSPVPHSEIVTTTTHKTLRGPRGG 237 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI R+ +N+ +FPG+QGGP H I AVA +A E++ Sbjct: 238 MILCREA--------------HAKTLNSQIFPGIQGGPLEHVIAAKAVAFGEALRPEFKE 283 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 YQ +++ N+ AE L S G +VSGGTDNHL+LV+L+ K + G E+ L I NK Sbjct: 284 YQRRIVENAQVLAEGLKSAGLRLVSGGTDNHLMLVDLRPKKLTGKVAEEALGKAGITVNK 343 Query: 1308 NTVPGD-VSAMVPGGIRMGTPALTSRGFVEEDFAKVA 1415 N +P D M GIR+GTPAL++RG + VA Sbjct: 344 NMIPWDPEKPMTTSGIRVGTPALSTRGMGPREMTLVA 380
>Q8D7G5:GLYA2_VIBVU Serine hydroxymethyltransferase 2 - Vibrio vulnificus| Length = 431 Score = 323 bits (829), Expect = 1e-87 Identities = 182/399 (45%), Positives = 247/399 (61%), Gaps = 1/399 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L D + I+ E RQ + +ELI SEN S +VMQA G+ +TNKY+EGYPG RYYGG Sbjct: 18 LSATDDAVFAGIQAEFTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGG 77 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E + +RA + FN + NVQP SG+ AN V ALL+P D IM + L Sbjct: 78 CEHVDTVEAIAIERAKKLFNCEY----ANVQPHSGAQANGAVKLALLQPGDTIMGMSLDA 133 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG + + +F + Y +D+ T I+YD + AV +PK+I+AG SA Sbjct: 134 GGHLTHGARP-----ALSGKWFNAVQYGVDKETLEINYDDVRALAVEHKPKMIIAGGSAI 188 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R+ D+ + R+I D+ A+L+ DMAHI+GL+A G PSP +A VVTTTTHK+LRGPRG Sbjct: 189 PRVIDFAKFREIADEVGAILMVDMAHIAGLIATGAHPSPLPHAHVVTTTTHKTLRGPRGG 248 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI +EI K KIN+AVFPGLQGGP H I AVA +A E++ Sbjct: 249 MILTNH--EEIIK-----------KINSAVFPGLQGGPLMHVIAAKAVAFGEALGPEFKT 295 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y + V+ N+ AE L ++G DIV+GGTD HL+LV+L+ KG+ G++ E+ LE I NK Sbjct: 296 YIDSVIDNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNKAEEALERAGITCNK 355 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEF 1421 N +P D M+ G+R+GTPA TSRGF E+F + + Sbjct: 356 NGIPFDTEKPMITSGVRLGTPAGTSRGFGAEEFKLIGHW 394
>Q87I03:GLYA2_VIBPA Serine hydroxymethyltransferase 2 - Vibrio parahaemolyticus| Length = 431 Score = 323 bits (829), Expect = 1e-87 Identities = 188/451 (41%), Positives = 261/451 (57%), Gaps = 1/451 (0%) Frame = +3 Query: 228 LEEVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 407 L D + I+ E RQ + +ELI SEN S +VMQA G+ +TNKY+EGYPG RYYGG Sbjct: 18 LSATDDAVFAGIQAEFTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGG 77 Query: 408 NEYIDMAETLCQKRALEAFNLDPEKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPH 587 E++D E + +RA + FN + NVQP SG+ AN V ALL+P D I+ + L Sbjct: 78 CEHVDTVEAIAIERAKKLFNCEY----ANVQPHSGAQANGAVKLALLQPGDTILGMSLDA 133 Query: 588 GGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGLIDYDQLEKSAVLFRPKLIVAGASAY 767 GGHL+HG + + +F + Y +D T I+YD + A+ +PK+I+AG SA Sbjct: 134 GGHLTHGARP-----ALSGKWFNAVQYGVDRETLEINYDDVRALALEHKPKMIIAGGSAI 188 Query: 768 ARLYDYNRMRKICDKQKAVLLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGA 947 R D+ + R+I D+ A+L+ DMAHI+GL+A G PSP +A VVTTTTHK+LRGPRG Sbjct: 189 PRTIDFAKFREIADEVNAILMVDMAHIAGLIATGAHPSPLPHAHVVTTTTHKTLRGPRGG 248 Query: 948 MIFFRKGVKEINKQGKEVKYDFEDKINAAVFPGLQGGPHNHTITGLAVALKQATTQEYRA 1127 MI D KIN+AVFPGLQGGP H I AVA +A E++ Sbjct: 249 MILTN-------------HEDIIKKINSAVFPGLQGGPLMHVIAAKAVAFGEALGPEFKT 295 Query: 1128 YQEQVMSNSARFAESLTSKGYDIVSGGTDNHLVLVNLKKKGIDGSRVEKVLENVHIAANK 1307 Y + V++N+ AE L ++G DIV+GGTD HL+LV+L+ KG+ G++ E+ LE I NK Sbjct: 296 YIDSVINNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNKAEEALERAGITCNK 355 Query: 1308 NTVPGDV-SAMVPGGIRMGTPALTSRGFVEEDFAKVAEFFDSXXXXXXXXXXXXXGTKLK 1484 N +P D M+ GIR+GTPA TSRGF E+F + + G L Sbjct: 356 NGIPFDTEKPMITSGIRLGTPAGTSRGFGAEEFKLIGNWI---------------GDVLD 400 Query: 1485 DFVATLQSDSNIQAEIAKLRHDVEEYAKQFP 1577 V + D+ ++ ++R +V+E +FP Sbjct: 401 GLVNNPEGDAIVE---KRVRKEVKELCSRFP 428 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 351,676,473 Number of extensions: 8149668 Number of successful extensions: 24431 Number of sequences better than 10.0: 365 Number of HSP's gapped: 22998 Number of HSP's successfully gapped: 370 Length of query: 656 Length of database: 100,686,439 Length adjustment: 120 Effective length of query: 536 Effective length of database: 67,771,039 Effective search space: 36325276904 Effective search space used: 36325276904 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
