>Q9LDU6:ST7R_ARATH 7-dehydrocholesterol reductase - Arabidopsis thaliana (Mouse-ear|
            cress)
          Length = 432
 Score =  692 bits (1785), Expect = 0.0
 Identities = 317/432 (73%), Positives = 357/432 (82%)
 Frame = +1

Query: 91   SKTAHSPLLTYASMVTLLSLCPPFVILLWYTMVHADGSVLQIYEHLRDHGILEGLKAIWP 270
            ++T HSP++TYASM++LL+ CPPFVILLWYTMVH DGSV Q +    ++G+ +GL  IWP
Sbjct: 2    AETVHSPIVTYASMLSLLAFCPPFVILLWYTMVHQDGSVTQTFGFFWENGV-QGLINIWP 60

Query: 271  APTLVAGKIIXXXXXXXXXXXXXXPGKRFEGPISPSGNVPVYKANGXXXXXXXXXXXXXX 450
             PTL+A KII              PGKR EGPISP+GN PVYKANG              
Sbjct: 61   RPTLIAWKIIFCYGAFEAILQLLLPGKRVEGPISPAGNRPVYKANGLAAYFVTLATYLGL 120

Query: 451  WWFGIFNPAIVYDHLGEIYSALVFGSLVFCLLLYIKGHVAPSSSDSGSAGNVIIDFYWGM 630
            WWFGIFNPAIVYDHLGEI+SAL+FGS +FC+LLYIKGHVAPSSSDSGS GN+IIDFYWGM
Sbjct: 121  WWFGIFNPAIVYDHLGEIFSALIFGSFIFCVLLYIKGHVAPSSSDSGSCGNLIIDFYWGM 180

Query: 631  ELYPRIGKHFDIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGRVADSMLVNTALMLIYITK 810
            ELYPRIGK FDIKVFTNCRFGMMSWAVLAVTYCIKQYE+NG+V+DSMLVNT LML+Y+TK
Sbjct: 181  ELYPRIGKSFDIKVFTNCRFGMMSWAVLAVTYCIKQYEINGKVSDSMLVNTILMLVYVTK 240

Query: 811  FFWWESGYWCTMDIAHDRAGFYICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLA 990
            FFWWE+GYW TMDIAHDRAGFYICWGCLVWVPS+YTSPGMYLVNHPV LG QLA+ IL+A
Sbjct: 241  FFWWEAGYWNTMDIAHDRAGFYICWGCLVWVPSVYTSPGMYLVNHPVELGTQLAIYILVA 300

Query: 991  GILCIYINYDCDRQRQEFRRTNGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFS 1170
            GILCIYINYDCDRQRQEFRRTNGK  VWG+APSKI+ASY TT GETKTSLLLTSGWWG +
Sbjct: 301  GILCIYINYDCDRQRQEFRRTNGKCLVWGRAPSKIVASYTTTSGETKTSLLLTSGWWGLA 360

Query: 1171 RHFHYAPEILAAFFWTVPALFTHFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYC 1350
            RHFHY PEIL+AFFWTVPALF +F+ YFYVIFLT+            C +KYGKYWK+YC
Sbjct: 361  RHFHYVPEILSAFFWTVPALFDNFLAYFYVIFLTLLLFDRAKRDDDRCRSKYGKYWKLYC 420

Query: 1351 NRVPYRVVPGIY 1386
             +V YR++PGIY
Sbjct: 421  EKVKYRIIPGIY 432

>Q7ZXH1:DHCR7_XENLA 7-dehydrocholesterol reductase - Xenopus laevis (African clawed frog)|
          Length = 473

 Score =  251 bits (641), Expect = 7e-66
 Identities = 127/345 (36%), Positives = 194/345 (56%), Gaps = 2/345 (0%)
 Frame = +1

Query: 358  EGPISPSGNVPVYKANGXXXXXXXXXXXXXX-WWFGIFNPAIVYDH-LGEIYSALVFGSL 531
            EG  +P+G +  Y+ NG               + F  F+P IV D+ +  ++ A + G  
Sbjct: 129  EGARTPAGLINKYQVNGLQAWTITHLLWFANAYHFHWFSPTIVIDNWIPLLWCANLLGYS 188

Query: 532  VFCLLLYIKGHVAPSSSDSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFGMMSWAV 711
            V    L        +++D    GN   D+  G+E  PRIGK FD K+F N R G+++W +
Sbjct: 189  VATFALVKANFFPTNANDCKFTGNFFYDYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTL 248

Query: 712  LAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGFYICWGC 891
            + ++Y  KQ E+ G+V +SM++   L  IY+  FFW ES Y  T+DI HD  G+Y+ WG 
Sbjct: 249  INLSYAAKQQELYGQVTNSMILVNVLQAIYVVDFFWNESWYLKTIDICHDHFGWYLGWGD 308

Query: 892  LVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRTNGKATV 1071
             VW+P +YT  G+YLV +PV L    A+++LL G++  YI    + Q+  FRRTNG   +
Sbjct: 309  CVWLPYLYTLQGLYLVYNPVELSTTAAVAVLLLGLIGYYIFRMTNHQKDLFRRTNGNCKI 368

Query: 1072 WGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALFTHFMPY 1251
            WGK P  I   Y +  G+   S L+ SG+WG +RH +Y  +++ +  + +   F H +PY
Sbjct: 369  WGKKPKSIECFYVSADGKRHYSKLMISGFWGVARHLNYTGDLMGSLAYCLACGFDHLLPY 428

Query: 1252 FYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
            FY I++TI            CS+KYGK WK+Y + VPYR++PG++
Sbjct: 429  FYFIYMTILLVHRCIRDEHRCSSKYGKDWKLYTSAVPYRLLPGLF 473

>O88455:DHCR7_MOUSE 7-dehydrocholesterol reductase - Mus musculus (Mouse)|
          Length = 471

 Score =  251 bits (640), Expect = 9e-66
 Identities = 130/346 (37%), Positives = 198/346 (57%), Gaps = 3/346 (0%)
 Frame = +1

Query: 358  EGPISPSGNVPVYKANGXXXXXXXXXXXXXX-WWFGIFNPAIVYDH-LGEIYSALVFGSL 531
            EG I+P+G V  Y+ NG               +    F+P I++D+ +  ++ A + G  
Sbjct: 127  EGAITPAGVVNKYEVNGLQAWLITHILWFVNAYLLSWFSPTIIFDNWIPLLWCANILGYA 186

Query: 532  VFCLLLYIKGHVAPSSS-DSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFGMMSWA 708
            V    + IKG++ P+S+ D    GN   ++  G+E  PRIGK FD K+F N R G+++W 
Sbjct: 187  VSTFAM-IKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWT 245

Query: 709  VLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGFYICWG 888
            ++ +++  KQ E+ G V +SM++   L  IY+  FFW E+ Y  T+DI HD  G+Y+ WG
Sbjct: 246  LINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWG 305

Query: 889  CLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRTNGKAT 1068
              VW+P +YT  G+YLV HPV L    AL ILL G++  YI    + Q+  FRRT+G+  
Sbjct: 306  DCVWLPYLYTLQGLYLVYHPVQLSTPNALGILLLGLVGYYIFRMTNHQKDLFRRTDGRCL 365

Query: 1069 VWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALFTHFMP 1248
            +WGK P  I  SY +  G    S LL SG+WG +RHF+Y  +++ +  + +     H +P
Sbjct: 366  IWGKKPKAIECSYTSADGLKHHSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLP 425

Query: 1249 YFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
            YFY+I++TI            C+ KYG+ W+ Y   VPYR++PGI+
Sbjct: 426  YFYIIYMTILLTHRCLRDEHRCANKYGRDWERYTAAVPYRLLPGIF 471

>Q6P4M0:DHCR7_XENTR 7-dehydrocholesterol reductase - Xenopus tropicalis (Western clawed|
            frog) (Silurana tropicalis)
          Length = 473

 Score =  250 bits (638), Expect = 1e-65
 Identities = 128/346 (36%), Positives = 197/346 (56%), Gaps = 3/346 (0%)
 Frame = +1

Query: 358  EGPISPSGNVPVYKANGXXXXXXXXXXXXXX-WWFGIFNPAIVYDH-LGEIYSALVFGSL 531
            EG  +P+G +  Y+ NG               + F  F+P I+ D+ +  ++ A + G  
Sbjct: 129  EGARTPAGLINKYQVNGLQAWTITHLLWFANAYHFHWFSPTIIIDNWVPLLWCANLLGYS 188

Query: 532  VFCLLLYIKGHVAPSSS-DSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFGMMSWA 708
            V    L +K +  P+++ D    GN   D+  G+E  PRIGK FD K+F N R G+++W 
Sbjct: 189  VATFAL-LKAYFFPTNAHDCKFTGNFFYDYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWT 247

Query: 709  VLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGFYICWG 888
            ++ ++Y  KQ E+ G+V +SM++   L  IY+  FFW ES Y  T+DI HD  G+Y+ WG
Sbjct: 248  LINLSYAAKQQELYGQVTNSMILVNVLQAIYVVDFFWNESWYLKTIDICHDHFGWYLGWG 307

Query: 889  CLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRTNGKAT 1068
              VW+P +YT  G+YLV +PV L    A+ +LL G++  YI    + Q+  FRRTNG   
Sbjct: 308  DCVWLPYLYTLQGLYLVYNPVELSTATAVGVLLLGLIGYYIFRMTNHQKDLFRRTNGNCK 367

Query: 1069 VWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALFTHFMP 1248
            +WGK P  I  SY +  G+   S L+ SG+WG +RH +Y  +++ +  + +   F H +P
Sbjct: 368  IWGKKPKSIECSYTSADGKRHYSKLMISGFWGVARHLNYTGDLMGSLAYCLACGFDHLLP 427

Query: 1249 YFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
            YFY  ++TI            CS+KYGK WK+Y + VPYR++PG++
Sbjct: 428  YFYFTYMTILLVHRCIRDEHRCSSKYGKDWKLYTDAVPYRLLPGLF 473

>Q9Z2Z8:DHCR7_RAT 7-dehydrocholesterol reductase - Rattus norvegicus (Rat)|
          Length = 471

 Score =  249 bits (637), Expect = 2e-65
 Identities = 129/346 (37%), Positives = 197/346 (56%), Gaps = 3/346 (0%)
 Frame = +1

Query: 358  EGPISPSGNVPVYKANGXXXXXXXXXXXXXX-WWFGIFNPAIVYDH-LGEIYSALVFGSL 531
            EG I+P+G V  Y+ NG               +    F+P I++D+ +  ++ A + G  
Sbjct: 127  EGAITPAGIVNKYEVNGLQAWLITHFLWFVNAYLLSWFSPTIIFDNWIPLLWCANILGYA 186

Query: 532  VFCLLLYIKGHVAPSSS-DSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFGMMSWA 708
            V    + IKG++ P+S+ D    GN   ++  G+E  PRIGK FD K+F N R G+++W 
Sbjct: 187  VSTFAM-IKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWT 245

Query: 709  VLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGFYICWG 888
            ++ +++  KQ E+ G V +SM++   L  IY+  FFW E+ Y  T+DI HD  G+Y+ WG
Sbjct: 246  LINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWG 305

Query: 889  CLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRTNGKAT 1068
              VW+P +YT  G+YLV HPV L    AL +LL G++  YI    + Q+  FRRT+G   
Sbjct: 306  DCVWLPYLYTLQGLYLVYHPVQLSTPNALGVLLLGLVGYYIFRMTNHQKDLFRRTDGHCL 365

Query: 1069 VWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALFTHFMP 1248
            +WGK P  I  SY +  G    S LL SG+WG +RHF+Y  +++ +  + +     H +P
Sbjct: 366  IWGKKPKAIECSYTSADGLKHRSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLP 425

Query: 1249 YFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
            YFY+I++TI            C+ KYG+ W+ Y   VPYR++PGI+
Sbjct: 426  YFYIIYMTILLTHRCLRDEHRCANKYGRDWERYVAAVPYRLLPGIF 471

>Q5E9J5:DHCR7_BOVIN 7-dehydrocholesterol reductase - Bos taurus (Bovine)|
          Length = 475

 Score =  249 bits (635), Expect = 3e-65
 Identities = 128/351 (36%), Positives = 199/351 (56%), Gaps = 8/351 (2%)
 Frame = +1

Query: 358  EGPISPSGNVPVYKANGXXXXXXXXXXXXXXWWF------GIFNPAIVYDH-LGEIYSAL 516
            EG ++P+G V  Y+ NG               WF      G F+P I++D+ +  ++ A 
Sbjct: 131  EGAVTPAGAVNKYEINGLQAWLLTHLL-----WFANAHLLGWFSPTIIFDNWIPLLWCAN 185

Query: 517  VFGSLVFCLLLYIKGHVAPSSS-DSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFG 693
            + G  V    + +KG++ P+ + +    GN   ++  G+E  PRIGK FD K+F N R G
Sbjct: 186  ILGYTVSTFAM-VKGYLFPTDARECKFTGNFFYNYMMGVEFNPRIGKWFDFKLFFNGRPG 244

Query: 694  MMSWAVLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGF 873
            +++W ++ +++  KQ E+ G V +SM++   L  IY+  FFW E+ Y  T+DI HD  G+
Sbjct: 245  IVAWTLINLSFAAKQQELYGHVTNSMVLVNILQAIYVLDFFWNETWYLKTIDICHDHFGW 304

Query: 874  YICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRT 1053
            Y+ WG  VW+P +YT  G+YLV HPV L    AL +LL G+L  YI    + Q+  FRRT
Sbjct: 305  YLGWGDCVWLPYLYTLQGLYLVYHPVQLPTYYALGVLLLGLLGYYIFRMTNHQKDLFRRT 364

Query: 1054 NGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALF 1233
            +G+  +WG+ P  I  SY +  G+   S LL SG+WG +RHF+Y  +++ +  + +    
Sbjct: 365  DGRCLIWGRKPKAIECSYTSADGQRHHSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGG 424

Query: 1234 THFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
             H +PYFY+IF+ I            C+ KYG+ W+ Y   VPYR++PGI+
Sbjct: 425  GHLLPYFYIIFMAILLTHRCLRDEHRCANKYGRDWEHYTAAVPYRLLPGIF 475

>Q9UBM7:DHCR7_HUMAN 7-dehydrocholesterol reductase - Homo sapiens (Human)|
          Length = 475

 Score =  243 bits (621), Expect = 1e-63
 Identities = 124/351 (35%), Positives = 199/351 (56%), Gaps = 8/351 (2%)
 Frame = +1

Query: 358  EGPISPSGNVPVYKANGXXXXXXXXXXXXXXWWFGI------FNPAIVYDH-LGEIYSAL 516
            EG ++P+G V  Y+ NG               WF        F+P I++D+ +  ++ A 
Sbjct: 131  EGAVTPAGVVNKYQINGLQAWLLTHLL-----WFANAHLLSWFSPTIIFDNWIPLLWCAN 185

Query: 517  VFGSLVFCLLLYIKGHVAPSSS-DSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFG 693
            + G  V    + +KG+  P+S+ D    GN   ++  G+E  PRIGK FD K+F N R G
Sbjct: 186  ILGYAVSTFAM-VKGYFFPTSARDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPG 244

Query: 694  MMSWAVLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGF 873
            +++W ++ +++  KQ E++  V ++M++   L  IY+  FFW E+ Y  T+DI HD  G+
Sbjct: 245  IVAWTLINLSFAAKQRELHSHVTNAMVLVNVLQAIYVIDFFWNETWYLKTIDICHDHFGW 304

Query: 874  YICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRT 1053
            Y+ WG  VW+P +YT  G+YLV HPV L    A+ +LL G++  YI    + Q+  FRRT
Sbjct: 305  YLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPHAVGVLLLGLVGYYIFRVANHQKDLFRRT 364

Query: 1054 NGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALF 1233
            +G+  +WG+ P  I  SY +  G+   S LL SG+WG +RHF+Y  +++ +  + +    
Sbjct: 365  DGRCLIWGRKPKVIECSYTSADGQRHHSKLLVSGFWGVARHFNYVGDLMGSLAYCLACGG 424

Query: 1234 THFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
             H +PYFY+I++ I            C++KYG+ W+ Y   VPYR++PGI+
Sbjct: 425  GHLLPYFYIIYMAILLTHRCLRDEHRCASKYGRDWERYTAAVPYRLLPGIF 475

>Q7SXF1:DHCR7_DANRE 7-dehydrocholesterol reductase - Danio rerio (Zebrafish) (Brachydanio|
            rerio)
          Length = 478

 Score =  235 bits (599), Expect = 5e-61
 Identities = 120/346 (34%), Positives = 192/346 (55%), Gaps = 3/346 (0%)
 Frame = +1

Query: 358  EGPISPSGNVPVYKANGXXXXXXXXXXXXXX-WWFGIFNPAIVYDH-LGEIYSALVFGSL 531
            +G  +P+G +  Y+ NG                 F  F+P I+ D+ +  ++   + G  
Sbjct: 134  DGARTPAGLINKYEVNGLQCWLITHVLWVLNAQHFHWFSPTIIIDNWIPLLWCTNILGYA 193

Query: 532  VFCLLLYIKGHVAPSS-SDSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFGMMSWA 708
            V     +IK ++ P++  D    GN+  ++  G+E  PRIGK FD K+F N R G+++W 
Sbjct: 194  V-STFAFIKAYLFPTNPEDCKFTGNMFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWT 252

Query: 709  VLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGFYICWG 888
            ++ ++Y  KQ E+ G V +SM++   L  +Y+  FFW E+ Y  T+DI HD  G+Y+ WG
Sbjct: 253  LINLSYAAKQQELYGYVTNSMILVNVLQAVYVVDFFWNEAWYLKTIDICHDHFGWYLGWG 312

Query: 889  CLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRTNGKAT 1068
              VW+P +YT  G+YLV +P+ L    A  +L+ G++  YI    + Q+  FRRT G  +
Sbjct: 313  DCVWLPFLYTLQGLYLVYNPIQLSTPHAAGVLILGLVGYYIFRVTNHQKDLFRRTEGNCS 372

Query: 1069 VWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALFTHFMP 1248
            +WGK P+ I  SYQ+  G    S L+TSG+WG +RH +Y  +++ +  + +     H +P
Sbjct: 373  IWGKKPTFIECSYQSADGAIHKSKLMTSGFWGVARHMNYTGDLMGSLAYCLACGGNHLLP 432

Query: 1249 YFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
            YFY+I++TI            CS KYGK W+ Y   V YR++P I+
Sbjct: 433  YFYIIYMTILLVHRCIRDEHRCSNKYGKDWERYTAAVSYRLLPNIF 478

>Q5UQI4:DHCR7_MIMIV Probable 7-dehydrocholesterol reductase - Mimivirus|
          Length = 447

 Score =  219 bits (557), Expect = 4e-56
 Identities = 120/343 (34%), Positives = 183/343 (53%), Gaps = 1/343 (0%)
 Frame = +1

Query: 361  GPISPSGNVPVYKANGXXXXXXXXXXXXXXWWFGIFNPAIVYDHLGEIYSALVFGSLVFC 540
            G I+P+GN+  Y  NG               ++G+F+P I+ D+ G I+ ++     +  
Sbjct: 113  GHITPAGNLVYYNINGLQAFIITHVLVIMSCYYGLFSPTIIMDNWGSIFWSVNIIGYLIT 172

Query: 541  LLLYIKGHVAPSS-SDSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFGMMSWAVLA 717
             L Y K     S  SD+   G +  D   G+E  P I    D+K+F N R G+++W ++ 
Sbjct: 173  FLAYFKALTFSSHPSDNKFTGKLFYDIVMGIEFNPEIFGT-DLKLFFNGRPGIIAWNLIN 231

Query: 718  VTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGFYICWGCLV 897
            ++  +KQYE  G V++SM++   L LIYI  FF+ E+ Y  T+DIAHD  G+ + WG  V
Sbjct: 232  LSCAMKQYENFGYVSNSMILVIILQLIYIVDFFYNENWYVHTVDIAHDHFGWMLAWGDTV 291

Query: 898  WVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRTNGKATVWG 1077
            W+P  YT    YL+N+P++L       + + GI+   I    + Q+ ++R          
Sbjct: 292  WLPFGYTLQAGYLMNNPIDLSTGFFNLVFVMGIIGYIIFRTANYQKDKYRSNT------- 344

Query: 1078 KAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALFTHFMPYFY 1257
            +    I  +YQT  G  + S L+ SG WG SRH +Y  +I+ +  + +   F+HF+PYFY
Sbjct: 345  QGVKYIPCTYQTADGLNRASKLIYSGLWGVSRHMNYTGDIILSTAYCLACGFSHFIPYFY 404

Query: 1258 VIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
             +++TI            CS KYGKYWKMY  RVPYR +PGIY
Sbjct: 405  CVYMTILLVTRCLRDEQRCSRKYGKYWKMYTKRVPYRFIPGIY 447

>O08984:LBR_RAT Lamin-B receptor - Rattus norvegicus (Rat)|
          Length = 620

 Score =  194 bits (494), Expect = 7e-49
 Identities = 110/306 (35%), Positives = 158/306 (51%), Gaps = 4/306 (1%)
 Frame = +1

Query: 481  VYDHLGEIYSALVFGSLVFCLLLYIKGHVAPSSSDS-GSAGNVIIDFYWGMELYPRIGKH 657
            +Y H  +   A +  S+V  + LY +    P    S  S+GN + DF+ G EL PRIG  
Sbjct: 327  LYTHFLQFALAAIVFSVVLSVYLYARSLKVPRDELSPASSGNAVYDFFIGRELNPRIGA- 385

Query: 658  FDIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGRVADSM---LVNTALMLIYITKFFWWES 828
            FD+K F   R G++ W V+ +   + + ++  R A S+   LVN+   L+Y+    W+E 
Sbjct: 386  FDLKFFCELRPGLIGWVVINLVMLLAEMKVQERSAPSLAMTLVNS-FQLLYVVDALWFEE 444

Query: 829  GYWCTMDIAHDRAGFYICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIY 1008
                TMDI HD  GF + +G LVWVP  Y+    YLVNHP +L   L  S+++A  LC Y
Sbjct: 445  ALLTTMDIIHDGFGFMLAFGDLVWVPFTYSLQAFYLVNHPQDLSWPLT-SVIIALKLCGY 503

Query: 1009 INYDCDRQRQEFRRTNGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYA 1188
            + + C          N +   + K P+    ++  T   +    LL SGWWGF RH +Y 
Sbjct: 504  VIFRC---------ANSQKNAFRKNPTDPKLAHLKTIPTSTWKSLLVSGWWGFVRHPNYL 554

Query: 1189 PEILAAFFWTVPALFTHFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYR 1368
             +++ A  W++P  F H +PYFYVI+ T             C  KYG  W+ YC RVPYR
Sbjct: 555  GDLIMALAWSLPCGFNHILPYFYVIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYR 614

Query: 1369 VVPGIY 1386
            + P IY
Sbjct: 615  IFPYIY 620

>Q3U9G9:LBR_MOUSE Lamin-B receptor - Mus musculus (Mouse)|
          Length = 626

 Score =  192 bits (488), Expect = 4e-48
 Identities = 114/350 (32%), Positives = 171/350 (48%), Gaps = 3/350 (0%)
 Frame = +1

Query: 346  GKRFEGPISPSGNVPVYKANGXXXXXXXXXXXXXXWWFGIFNPAIVYDHLGEIYSALVFG 525
            GK  EG     G    Y+ NG               ++G+     +Y H  ++  A    
Sbjct: 289  GKVAEGTPLVDGRRLQYRLNGLYAFILTSAALGAAVFWGV-ELCYLYTHFLQLALAATGF 347

Query: 526  SLVFCLLLYIKGHVAPSSSDS-GSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFGMMS 702
            S++    LY++   AP    S  S+GN + DF+ G EL PR+G  FD+K F   R G++ 
Sbjct: 348  SVLLSAYLYVRSLRAPREELSPASSGNAVYDFFIGRELNPRLGA-FDLKFFCELRPGLIG 406

Query: 703  WAVLAVTYCIKQYEMNGRVADS--MLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGFY 876
            W V+ +   + + ++  R A S  M++  +  L+Y+    W E     +MDI HD  GF 
Sbjct: 407  WVVINLVMLLMEMKIQERAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFM 466

Query: 877  ICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRTN 1056
            + +G LVWVP  Y+    YLV+HP +L   LA S+++A  LC Y+ + C          N
Sbjct: 467  LAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLA-SVIIALKLCGYVIFRC---------AN 516

Query: 1057 GKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALFT 1236
             +   + K P+    ++  T   +    LL SGWWGF RH +Y  +++ A  W++P  F 
Sbjct: 517  SQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFN 576

Query: 1237 HFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
            H +PYFY+I+ T             C  KYG  W+ YC RVPYR+ P IY
Sbjct: 577  HLLPYFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY 626

>Q14739:LBR_HUMAN Lamin-B receptor - Homo sapiens (Human)|
          Length = 615

 Score =  192 bits (488), Expect = 4e-48
 Identities = 107/305 (35%), Positives = 157/305 (51%), Gaps = 3/305 (0%)
 Frame = +1

Query: 481  VYDHLGEIYSALVFGSLVFCLLLYIKGHVAPSSSDS-GSAGNVIIDFYWGMELYPRIGKH 657
            VY H  +   A     +V  + LY++   AP +  S  S+GN + DF+ G EL PRIG  
Sbjct: 322  VYSHFLQFALAATVFCVVLSVYLYMRSLKAPRNDLSPASSGNAVYDFFIGRELNPRIGT- 380

Query: 658  FDIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGRVADS--MLVNTALMLIYITKFFWWESG 831
            FD+K F   R G++ W V+ +   + + ++  R   S  M++  +  L+Y+    W E  
Sbjct: 381  FDLKYFCELRPGLIGWVVINLVMLLAEMKIQDRAVPSLAMILVNSFQLLYVVDALWNEEA 440

Query: 832  YWCTMDIAHDRAGFYICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYI 1011
               TMDI HD  GF + +G LVWVP IY+    YLV+HP  +   +A S+++   LC Y+
Sbjct: 441  LLTTMDIIHDGFGFMLAFGDLVWVPFIYSFQAFYLVSHPNEVSWPMA-SLIIVLKLCGYV 499

Query: 1012 NYDCDRQRQEFRRTNGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAP 1191
                      FR  N +   + K PS    ++  T   +    LL SGWWGF RH +Y  
Sbjct: 500  I---------FRGANSQKNAFRKNPSDPKLAHLKTIHTSTGKNLLVSGWWGFVRHPNYLG 550

Query: 1192 EILAAFFWTVPALFTHFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRV 1371
            +++ A  W++P  F H +PYFY+I+ T+            C  KYG  W+ YC RVPYR+
Sbjct: 551  DLIMALAWSLPCGFNHILPYFYIIYFTMLLVHREARDEYHCKKKYGVAWEKYCQRVPYRI 610

Query: 1372 VPGIY 1386
             P IY
Sbjct: 611  FPYIY 615

>Q5R7H4:LBR_PONPY Lamin-B receptor - Pongo pygmaeus (Orangutan)|
          Length = 615

 Score =  189 bits (479), Expect = 4e-47
 Identities = 105/305 (34%), Positives = 156/305 (51%), Gaps = 3/305 (0%)
 Frame = +1

Query: 481  VYDHLGEIYSALVFGSLVFCLLLYIKGHVAPSSSDS-GSAGNVIIDFYWGMELYPRIGKH 657
            VY H  +   A     +V  + LY++   AP +  S  S+GN + DF+ G EL PRIG  
Sbjct: 322  VYSHFLQFALAATVFCVVLSVYLYMRSLKAPRNDLSPASSGNAVYDFFIGRELNPRIGT- 380

Query: 658  FDIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGRVADS--MLVNTALMLIYITKFFWWESG 831
            FD+K F   R G++ W V+ +   + + ++  R   S  M++  +  L+Y+    W E  
Sbjct: 381  FDLKYFCELRPGLIGWVVINLVMLLAEMKIQDRAVPSLAMILVNSFQLLYVVDALWNEEA 440

Query: 832  YWCTMDIAHDRAGFYICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYI 1011
               TMDI HD  GF + +G LVWVP IY+    YLV+HP  +   +A S+++    C Y+
Sbjct: 441  LLTTMDIIHDGFGFMLAFGDLVWVPFIYSFQAFYLVSHPNEVSWPMA-SLIIVLKFCGYV 499

Query: 1012 NYDCDRQRQEFRRTNGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAP 1191
                      FR  N +   + K PS    ++  T   +    LL SGWWGF+RH +Y  
Sbjct: 500  I---------FRGANSQKNAFRKNPSDPKLAHLKTIHTSTGKNLLVSGWWGFARHPNYLG 550

Query: 1192 EILAAFFWTVPALFTHFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRV 1371
            +++ A  W++   F H +PYFY+I+ T+            C  KYG  W+ YC RVPYR+
Sbjct: 551  DLIMALAWSLACGFNHILPYFYIIYFTMLLVHREARDEYHCKKKYGVAWEKYCQRVPYRI 610

Query: 1372 VPGIY 1386
             P IY
Sbjct: 611  FPYIY 615

>Q8WMV1:ERG24_BOVIN Delta(14)-sterol reductase - Bos taurus (Bovine)|
          Length = 418

 Score =  187 bits (475), Expect = 1e-46
 Identities = 103/294 (35%), Positives = 147/294 (50%), Gaps = 2/294 (0%)
 Frame = +1

Query: 511  ALVFGSLVFCLLLYIKGHVAPSSS--DSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNC 684
            A    + +F LLLY+K  +AP+S+    G++GN+I DF+ G EL PRI   FD K F   
Sbjct: 136  AATLTAFIFSLLLYLKALLAPASALAPGGNSGNLIYDFFLGRELNPRICS-FDFKYFCEL 194

Query: 685  RFGMMSWAVLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDR 864
            R G++ W ++ +   I++ E+ G  + +M +     L+Y+    W+E     TMDI HD 
Sbjct: 195  RPGLIGWVLINLALLIQEAELRGSPSLAMWLVNGFQLLYVGDALWYEEAVLTTMDIIHDG 254

Query: 865  AGFYICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEF 1044
             GF + +G L WVP  Y+    +L+ HP  LG  LA  I L   +  YI          F
Sbjct: 255  FGFMLAFGDLAWVPFTYSLQAQFLLYHPQPLGWPLASFICLINAVGYYI----------F 304

Query: 1045 RRTNGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVP 1224
            R  N +   + K PS    +   T        LL SGWWG  RH +Y  +++ A  W++P
Sbjct: 305  RGANSQKNTFRKNPSDPRVADLETISTATGRRLLVSGWWGMVRHPNYLGDLIMALAWSLP 364

Query: 1225 ALFTHFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
                H +PYFY ++ T             C  KYG  W  YC RVPYR+VP +Y
Sbjct: 365  CGVFHLLPYFYFLYFTALLVHREDRDERQCRQKYGLAWHEYCRRVPYRIVPYVY 418

>O76062:ERG24_HUMAN Delta(14)-sterol reductase - Homo sapiens (Human)|
          Length = 418

 Score =  186 bits (471), Expect = 3e-46
 Identities = 100/289 (34%), Positives = 147/289 (50%), Gaps = 2/289 (0%)
 Frame = +1

Query: 526  SLVFCLLLYIKGHVAPSSS--DSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFGMM 699
            + +F L LY+K  VAP S+    G++GN I DF+ G EL PRI   FD K F   R G++
Sbjct: 141  AFIFSLFLYMKAQVAPVSALAPGGNSGNPIYDFFLGRELNPRIC-FFDFKYFCELRPGLI 199

Query: 700  SWAVLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGFYI 879
             W ++ +   +K+ E+ G  + +M +     L+Y+    W E     TMDI HD  GF +
Sbjct: 200  GWVLINLALLMKEAELRGSPSLAMWLVNGFQLLYVGDALWHEEAVLTTMDITHDGFGFML 259

Query: 880  CWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRTNG 1059
             +G + WVP  Y+    +L++HP  LG  +A  I L      YI    + Q+  FR+   
Sbjct: 260  AFGDMAWVPFTYSLQAQFLLHHPQPLGLPMASVICLINATGYYIFRGANSQKNTFRKNPS 319

Query: 1060 KATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALFTH 1239
               V G      + +  T  G      LL SGWWG  RH +Y  +++ A  W++P   +H
Sbjct: 320  DPRVAG------LETISTATGRK----LLVSGWWGMVRHPNYLGDLIMALAWSLPCGVSH 369

Query: 1240 FMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
             +PYFY+++ T             C  KYG  W+ YC RVPYR++P IY
Sbjct: 370  LLPYFYLLYFTALLVHREARDERQCLQKYGLAWQEYCRRVPYRIMPYIY 418

>P23913:LBR_CHICK Lamin-B receptor - Gallus gallus (Chicken)|
          Length = 637

 Score =  182 bits (461), Expect = 5e-45
 Identities = 100/299 (33%), Positives = 153/299 (51%), Gaps = 4/299 (1%)
 Frame = +1

Query: 481  VYDHLGEIYSALVFGSLVFCLLLYIKGHVAPSS--SDSGSAGNVIIDFYWGMELYPRIGK 654
            +YDH  +   +    S+   + LYI+   AP    +  G++G ++ DF+ G EL PRIG 
Sbjct: 314  LYDHFVQFAVSAAAFSMALSIYLYIRSLKAPEEDLAPGGNSGYLVYDFFTGHELNPRIGS 373

Query: 655  HFDIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGRVADS--MLVNTALMLIYITKFFWWES 828
             FD+K F   R G++ W V+ +   + + +++ +   S  M++  +  L+Y+    W E 
Sbjct: 374  -FDLKYFCELRPGLIGWVVINLAMLLAEMKIHNQSMPSLSMILVNSFQLLYVVDALWNEE 432

Query: 829  GYWCTMDIAHDRAGFYICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIY 1008
                TMDI HD  GF + +G LVWVP +Y+    YLV HP+ +   +A +I +   +  Y
Sbjct: 433  AVLTTMDITHDGFGFMLAFGDLVWVPFVYSLQAFYLVGHPIAISWPVAAAITILNCIGYY 492

Query: 1009 INYDCDRQRQEFRRTNGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYA 1188
            I    + Q+  FRR      +   +  K+I +  T KG      LL +GWWGF RH +Y 
Sbjct: 493  IFRSANSQKNNFRRNPADPKL---SYLKVIPT-ATGKG------LLVTGWWGFVRHPNYL 542

Query: 1189 PEILAAFFWTVPALFTHFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPY 1365
             +I+ A  W++P  F H +PYFYVI+               C  KYG  W+ YC RVPY
Sbjct: 543  GDIIMALAWSLPCGFNHILPYFYVIYFICLLVHREARDEHHCKKKYGLAWERYCQRVPY 601

>Q09195:ERG24_SCHPO Delta(14)-sterol reductase - Schizosaccharomyces pombe (Fission|
            yeast)
          Length = 424

 Score =  179 bits (453), Expect = 4e-44
 Identities = 112/351 (31%), Positives = 167/351 (47%), Gaps = 4/351 (1%)
 Frame = +1

Query: 346  GKRFEG-PISPSGNVPVYKANGXXXXXXXXXXXXXX-WWFGIFNPAIVYDHLGEIYSALV 519
            GK  +G PI   G   +YK NG               +  G      ++D+  ++  A  
Sbjct: 85   GKWAKGTPIDDKGTRLLYKINGFNSACLILGVVCTSIYLLGASCMEFIWDNFLQLMFAAY 144

Query: 520  FGSLVFCLLLYIKGHVAPSS-SDSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFGM 696
              S+V C   Y++        +  G++GN++ D++ G  L PRIG +FDIK F   R G+
Sbjct: 145  VFSVVLCTFCYVQSFFGKQQLAKGGTSGNILFDWFIGRSLNPRIG-NFDIKCFCELRPGL 203

Query: 697  MSWAVLAVTYCIKQY-EMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGF 873
            + W V  + +   QY  + GR+ DSM++       Y+      ES    TMDI  D  G+
Sbjct: 204  ILWVVFDIAFACHQYLVLGGRITDSMVLVIIFHTWYVLDSLINESAVLTTMDITTDGFGY 263

Query: 874  YICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRT 1053
             + +G LVWVP +Y+    YL  HPV+LG    L+IL    L  YI    + Q+  FR  
Sbjct: 264  MLSFGDLVWVPFLYSLQARYLAFHPVDLGLVKTLAILCLQFLGYYIFRGANGQKNRFRSN 323

Query: 1054 NGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALF 1233
                 +      K +   QT +G    + LLTSGWWG +RH +Y  + + A+ W +PA F
Sbjct: 324  PNDPKL------KHLKFIQTKRG----TKLLTSGWWGMARHINYFGDWIMAWAWCLPAGF 373

Query: 1234 THFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
               +PYFYV +  +            C  KYG+ W+ YC  V YR++P +Y
Sbjct: 374  GSPIPYFYVAYFGVLLVHRNARDDHKCRVKYGEDWEKYCKAVKYRIIPYVY 424

>P78575:ERG24_ASCIM Delta(14)-sterol reductase - Ascobolus immersus|
          Length = 430

 Score =  165 bits (417), Expect = 6e-40
 Identities = 105/322 (32%), Positives = 154/322 (47%), Gaps = 10/322 (3%)
 Frame = +1

Query: 451  WWFGIFNPAIVYDHLGEIYSALVFGSLVFCLLLYIKGHVAPSS------SDSGSAGNVII 612
            WWF  +    + D+  ++ SA +  S    L +YI+ +           S  G  GN I 
Sbjct: 127  WWFWSY----LTDNFAQLQSASIVFSYAMSLWVYIRSYRPMPKGKEVILSPVGFKGNHIH 182

Query: 613  DFYWGMELYPRIGKHFDIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGRVADSMLVNTALM 792
            DF+ G EL PRIG+  DIK     R G+M W +  + + +KQY  +G V+DS+++     
Sbjct: 183  DFWMGRELNPRIGEWLDIKQLHELRPGLMGWILFNLAWTVKQYNTHGFVSDSIVLVNLFE 242

Query: 793  LIYITKFFWWESGYWCTMDIAHDRAGFYICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLA 972
              Y+    W ES    TMDI  D  G  + +G  VWVP +Y     YL + PV+LG    
Sbjct: 243  TWYVVDALWNESKVLTTMDITTDGLGVMLLFGNAVWVPFMYCLQARYLASFPVHLG---- 298

Query: 973  LSILLAGILCI-YINYDCDRQRQEFRRTNGKATVWGKAPSKIIAS---YQTTKGETKTSL 1140
              + +AG+L + +  Y        FR  N +   +   P+    S   + TTK  +K   
Sbjct: 299  -LLGIAGVLAVQFTGYAI------FRGANNQKNAFRTNPADPAVSHLKFMTTKSGSK--- 348

Query: 1141 LLTSGWWGFSRHFHYAPEILAAFFWTVPALFTHFMPYFYVIFLTIXXXXXXXXXXXXCST 1320
            LL SGWWG +RH +Y  + + A+ + +   F   + YFYVI+  I            C  
Sbjct: 349  LLISGWWGVARHVNYFGDWIMAWSYCLTTGFNTPLTYFYVIYFGILLLHRDRRDEAKCRE 408

Query: 1321 KYGKYWKMYCNRVPYRVVPGIY 1386
            KYGK W  YC  V +R++PGIY
Sbjct: 409  KYGKDWDRYCKVVKWRIIPGIY 430

>Q9LDR4:ERG24_ARATH Delta(14)-sterol reductase - Arabidopsis thaliana (Mouse-ear cress)|
          Length = 369

 Score =  150 bits (378), Expect = 2e-35
 Identities = 98/354 (27%), Positives = 170/354 (48%), Gaps = 6/354 (1%)
 Frame = +1

Query: 343  PGKRFEGPISPSGNVPVYKANGXXXXXXXXXXXXXXWWFGIFNPAIVYDHLGEIYSALVF 522
            PGK   G +   G+   Y+ NG                 GI +P +V D   E+ SA   
Sbjct: 35   PGKVIRGVLLSDGSQLRYRCNGLLALILLVAILGICAKLGIVSPLVVADRGLELLSATFI 94

Query: 523  GSLVFCLLLYIKGHVAPSSSDSGSA------GNVIIDFYWGMELYPRIGKHFDIKVFTNC 684
              ++  L LY+ G    SSS+ GS+      GN++ D+++G++L P+     D+K F   
Sbjct: 95   FCVLVTLALYVTGR---SSSNKGSSLKPHVSGNLVHDWWFGIQLNPQF-MSIDLKFFF-V 149

Query: 685  RFGMMSWAVLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDR 864
            R GMM W ++ ++   K  + +G ++ SM++      +YI  +F  E     T DI  +R
Sbjct: 150  RAGMMGWLLINLSILAKSVQ-DGSLSQSMILYQIFCALYILDYFVHEEYMTSTWDIIAER 208

Query: 865  AGFYICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEF 1044
             GF + +G L+W+P  ++  G +L+++ V L     +   L  ++   +    ++Q+  F
Sbjct: 209  LGFMLVFGDLLWIPFTFSIQGWWLLHNKVELTVPAIVVNCLVFLIGYMVFRGANKQKHIF 268

Query: 1045 RRTNGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVP 1224
            ++ N K  +WGK P  +               LL SG+WG +RH +Y  +++ A  +++P
Sbjct: 269  KK-NPKTPIWGKPPVVVGGK------------LLVSGYWGIARHCNYLGDLMLALSFSLP 315

Query: 1225 ALFTHFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
               +  +PYFY I+L I            C+ KY + W  Y   VP+R++P +Y
Sbjct: 316  CGISSPVPYFYPIYLLILLIWRERRDEVRCAEKYKEIWAEYLRLVPWRILPYVY 369

>P38670:ERG24_NEUCR Delta(14)-sterol reductase - Neurospora crassa|
          Length = 490

 Score =  144 bits (363), Expect = 1e-33
 Identities = 98/345 (28%), Positives = 149/345 (43%), Gaps = 43/345 (12%)
 Frame = +1

Query: 481  VYDHLGEIYSALVFGSLVFCLLLYIKGH-VAPSSSD------SGSAGNVIIDFYWGMELY 639
            + D+  +I SA +  +    + +Y++   V P + D       G  G++I DFY G EL 
Sbjct: 156  ISDNFAQIISANILFAFALAIFVYVRSFDVKPGNKDMRQLAAGGVTGSLIYDFYIGRELN 215

Query: 640  PRIGK----HFDIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGRVADSMLVNTALMLIYIT 807
            PRI        DIK F   R G++ W +L   +  KQY + G V DS+L  TA+   Y+ 
Sbjct: 216  PRITLPLIGQVDIKEFMEMRPGLLGWIILNCAFIAKQYRLYGYVTDSILFITAIQAFYVF 275

Query: 808  KFFWWESGYWCTMDIAHDRAGFYICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILL 987
               + E     TMDI  D  GF + +G +VWVP +Y++   YL  HP  LG   A  ++ 
Sbjct: 276  DGIYMEPAVLTTMDITTDGFGFMLSFGDVVWVPFMYSTQTRYLSVHPQQLG---AFGLIA 332

Query: 988  AGILCIYINYDCDRQRQEFRRTNGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGF 1167
             G + +   Y        FR +N +   +   P      + T       S L+TSGWWG 
Sbjct: 333  VGAV-LAAGYSI------FRLSNSQKNNFRTNPEDPSVKHLTYLQTKTGSRLITSGWWGI 385

Query: 1168 SRHFHYAPEILAAFFWTVPALFTHF--------------------------------MPY 1251
            +RH +Y  + L ++ +++P     +                                  Y
Sbjct: 386  ARHINYLGDWLQSWPYSLPTGIAGYQILSAGSNAPGAITMLDGREVVQGEARGWGIVFTY 445

Query: 1252 FYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
            FY+++  I            CS KYG  W+ Y   V +R+VPGIY
Sbjct: 446  FYILYFAILLIHRDLRDDEKCSKKYGDDWEKYKKLVKWRIVPGIY 490

>O13597:ERG24_SEPLY Delta(14)-sterol reductase - Septoria lycopersici (Tomato leaf spot|
            fungus)
          Length = 512

 Score =  143 bits (360), Expect = 3e-33
 Identities = 93/312 (29%), Positives = 136/312 (43%), Gaps = 46/312 (14%)
 Frame = +1

Query: 589  GSAGNVIIDFYWGMELYPRIGKHF----DIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGR 756
            G +G+++ D+Y G EL PRI   F    DIK F   R GM+ W +L + +  KQY+  G 
Sbjct: 211  GHSGHILYDWYMGRELNPRITIPFIGEVDIKSFMELRPGMIGWVLLDLAFAAKQYKSYGY 270

Query: 757  VADSMLVNTALML-----------------IYITKFFWWESGYWCTMDIAHDRAGFYICW 885
            + DSM   T L+L                 +Y+    + E     TMD+  D  GF + +
Sbjct: 271  ITDSMRKWTPLLLGIHVLTIHPVIVIISQSVYVFDALYMEPAILTTMDLTTDGFGFMLSF 330

Query: 886  GCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILLAGILCIYINYDCDRQRQEFRRTNGKA 1065
            G LVWVP IY+    YL  HPV LGP     IL       YI          FR TN   
Sbjct: 331  GDLVWVPFIYSIQAKYLSVHPVALGPLYVALILTIQATGYYI----------FRATNNDK 380

Query: 1066 TVWGKAPSKIIASYQTTKGETKTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALFTHF- 1242
             ++   P+    ++         S LLT+GWWG +RH +Y  + L ++ + +P L   + 
Sbjct: 381  NIFRTNPNDPKVAHLKYIETGTGSRLLTTGWWGTARHINYLGDWLMSWSYCLPTLAAGYK 440

Query: 1243 ------------------------MPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYC 1350
                                    + YFY+++  I            C  KYG +W+ YC
Sbjct: 441  LTPTILFENSRLVSTDGMKGAGIPITYFYMLYFAILLIHRERRDEAKCRRKYGAHWEKYC 500

Query: 1351 NRVPYRVVPGIY 1386
              V +R++PG+Y
Sbjct: 501  QIVRWRILPGVY 512

>Q01447:ERG24_FUSSO Delta(14)-sterol reductase - Fusarium solani subsp. pisi (Nectria|
            haematococca)
          Length = 485

 Score =  142 bits (358), Expect = 4e-33
 Identities = 96/346 (27%), Positives = 154/346 (44%), Gaps = 44/346 (12%)
 Frame = +1

Query: 481  VYDHLGEIYSALVFGSLVFCLLLYIKGH-VAPSSSDS------GSAGNVIIDFYWGMELY 639
            + D+  +I +A    S      +Y++   V P + ++      G  GN++ D++ G EL 
Sbjct: 151  ISDNFIQILTANTIFSYAVATFVYVRSFSVKPGNKENRELAAGGHTGNMLYDWFIGRELN 210

Query: 640  PRIG----KHFDIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGRVADSMLVNTALMLIYIT 807
            PR+        D+K +   R GMM W +   ++C +QY   G V DS +  T +  +Y+ 
Sbjct: 211  PRVVIPLIGEVDLKEWLELRPGMMGWIIFNCSWCAQQYRNYGYVTDSSICITLVQAVYVF 270

Query: 808  KFFWWESGYWCTMDIAHDRAGFYICWGCLVWVPSIYTSPGMYLVNHPVNLGPQLALSILL 987
              +W E     TMDI  D  G  + +G +VWVP +Y+    YL  HPV+LGP + L+++L
Sbjct: 271  DSWWNEPAILTTMDITTDGFGMMLAFGDIVWVPFVYSLQTRYLAVHPVSLGP-VGLAVML 329

Query: 988  AGI-LCIYINYDCDRQRQEFRRTNGKATVWGKAPSKIIASYQTTKGETKTSLLLTSGWWG 1164
            + I L  YI    + ++  FR       V        +   QT KG    S LL SGWWG
Sbjct: 330  SLIGLGFYIFRSANSEKNNFRTNPNDPKV------SQLKYIQTKKG----SKLLISGWWG 379

Query: 1165 FSRHFHYAPEILAAFFWTVPALFTHF--------------------------------MP 1248
             +RH +Y  + + ++ + +P     +                                + 
Sbjct: 380  IARHINYLGDWIQSWPYCLPTGLAGYQILNAGAQAEGALVMRDGREVVQGEAKGWGMLIT 439

Query: 1249 YFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGIY 1386
            YFY+++  I            C  KYG+ W+ Y   V YR++PGIY
Sbjct: 440  YFYILYFAILLIHRERRDDDKCHRKYGEDWEKYRKIVRYRIIPGIY 485

>P32462:ERG24_YEAST Delta(14)-sterol reductase - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 438

 Score =  135 bits (340), Expect = 5e-31
 Identities = 82/266 (30%), Positives = 131/266 (49%)
 Frame = +1

Query: 589  GSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGRVADS 768
            G++GN+I D++ G EL PR+G   DIK+F+  R GM+ W ++ ++     Y   G++ D+
Sbjct: 188  GNSGNIIYDWFIGRELNPRLGP-LDIKMFSELRPGMLLWLLINLSCLHHHYLKTGKINDA 246

Query: 769  MLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGFYICWGCLVWVPSIYTSPGMYLVNHP 948
            +++   L   YI      E G    MDI  D  GF + +G L  VP  Y+    YL   P
Sbjct: 247  LVLVNFLQGFYIFDGVLNEEGVLTMMDITTDGFGFMLAFGDLSLVPFTYSLQARYLSVSP 306

Query: 949  VNLGPQLALSILLAGILCIYINYDCDRQRQEFRRTNGKATVWGKAPSKIIASYQTTKGET 1128
            V LG    + IL    L  +I +  ++Q+ EFR+        GK  +  + S QT +G  
Sbjct: 307  VELGWVKVVGILAIMFLGFHIFHSANKQKSEFRQ--------GKLEN--LKSIQTKRG-- 354

Query: 1129 KTSLLLTSGWWGFSRHFHYAPEILAAFFWTVPALFTHFMPYFYVIFLTIXXXXXXXXXXX 1308
              + LL  GWW  S+H +Y  + L +  W +   F   + Y+Y ++              
Sbjct: 355  --TKLLCDGWWAKSQHINYFGDWLISLSWCLATWFQTPLTYYYSLYFATLLLHRQQRDEH 412

Query: 1309 XCSTKYGKYWKMYCNRVPYRVVPGIY 1386
             C  KYG+ W+ Y  +VPY+++P +Y
Sbjct: 413  KCRLKYGENWEEYERKVPYKIIPYVY 438

>P36209:STS1_SCHPO Delta(24(24(1)))-sterol reductase - Schizosaccharomyces pombe|
            (Fission yeast)
          Length = 453

 Score =  108 bits (270), Expect = 7e-23
 Identities = 83/301 (27%), Positives = 126/301 (41%), Gaps = 10/301 (3%)
 Frame = +1

Query: 514  LVFGSLVFCLLLYIKGHVAPSSSDSGSAGNVIIDFYWGMELYPRIGKHFDIKVFTNCRFG 693
            L  G+L+F   L+ K H          +GN I D + G  L PR+GK  D K+F   R  
Sbjct: 165  LYTGTLLFGDRLFDKPHRL--------SGNPIYDAFMGACLNPRLGKLLDFKMFFEVRIP 216

Query: 694  MMSWAVLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWWESGYWCTMDIAHDRAGF 873
                  ++V   ++QYE  G V+  +L       +Y       E     T D+A+++ GF
Sbjct: 217  WFILFFISVGAAVRQYETYGTVSPQVLFVCLGHYLYANACSKGEQLIVPTWDMAYEKFGF 276

Query: 874  YICWGCLVWVPSIYTSPGMYLVNHP---VNLGPQLALSILLAGILCIYINYDCDRQRQEF 1044
             + +  +  VP  Y+   +YL +H     N   Q    I +  + C YI   C+ Q+  F
Sbjct: 277  MLIFWNMAGVPFTYSHCTLYLFSHDPSVYNWSTQYTTGIYVLLLCCYYIFDTCNGQKNHF 336

Query: 1045 RR----TNGKATVWGKAPSKIIAS---YQTTKGETKTSLLLTSGWWGFSRHFHYAPEILA 1203
            R     T      + + P  II +    +   G T    LLTSGW+ ++R  HY  +   
Sbjct: 337  RNQIYGTEVHRKTFPQLPWLIIKNPTFIRCANGGT----LLTSGWYRYARKIHYTADFFQ 392

Query: 1204 AFFWTVPALFTHFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKYWKMYCNRVPYRVVPGI 1383
            +  W +   F   +PYFY  F  +            C  KYG  +  YC   PY  +P I
Sbjct: 393  SLSWALITGFQSPLPYFYPCFFFVVLVHRVSRDIKKCKAKYGADFDEYCRICPYLFIPYI 452

Query: 1384 Y 1386
            +
Sbjct: 453  F 453

>P25340:ERG4_YEAST Delta(24(24(1)))-sterol reductase - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 473

 Score =  105 bits (262), Expect = 6e-22
 Identities = 79/317 (24%), Positives = 130/317 (41%), Gaps = 9/317 (2%)
 Frame = +1

Query: 463  IFNPAIVYDHLGEIYSALVFGSLVFCLLLYIKGHVAPSSSDSGSAGNVIIDFYWGMELYP 642
            +F   ++ D  G I +  +     F ++LY+   +  S       GN + DF+ G  L P
Sbjct: 162  LFRLYVIIDRFGRIMTCAIISGFAFSIILYL-WTLFISHDYHRMTGNHLYDFFMGAPLNP 220

Query: 643  RIGKHFDIKVFTNCRFGMMSWAVLAVTYCIKQYEMNGRVADSMLVNTALMLIYITKFFWW 822
            R G   D+K+F   R    +   + +  C+KQ+E  G V   + V      +Y       
Sbjct: 221  RWGI-LDLKMFFEVRLPWFTLYFITLGACLKQWETYGYVTPQLGVVMLAHWLYANACAKG 279

Query: 823  ESGYWCTMDIAHDRAGFYICWGCLVWVPSIYTSPGMYLVNH-PVNLGPQLALSI-LLAGI 996
            E     T D+A+++ GF + +  +  VP  Y    +YL  H P         ++ L   +
Sbjct: 280  EELIVPTWDMAYEKFGFMLIFWNIAGVPYTYCHCTLYLYYHDPSEYHWSTLYNVSLYVVL 339

Query: 997  LCIYINYD-CDRQRQEFRRTNGKATVWGKA----PSKIIAS--YQTTKGETKTSLLLTSG 1155
            LC Y  +D  + Q+  FR+         K     P +I+ +  Y  T   +  S LL  G
Sbjct: 340  LCAYYFFDTANAQKNAFRKQMSGDKTGRKTFPFLPYQILKNPKYMVT---SNGSYLLIDG 396

Query: 1156 WWGFSRHFHYAPEILAAFFWTVPALFTHFMPYFYVIFLTIXXXXXXXXXXXXCSTKYGKY 1335
            W+  +R  HY  +   +  W +   F    P+F+ +F  +            C  KYGK 
Sbjct: 397  WYTLARKIHYTADWTQSLVWALSCGFNSVFPWFFPVFFLVVLIHRAFRDQAKCKRKYGKD 456

Query: 1336 WKMYCNRVPYRVVPGIY 1386
            W  YC   PY  +P ++
Sbjct: 457  WDEYCKHCPYVFIPYVF 473

>P32825:SXA2_SCHPO Carboxypeptidase sxa2 precursor - Schizosaccharomyces pombe|
           (Fission yeast)
          Length = 507

 Score = 32.0 bits (71), Expect = 8.3
 Identities = 17/42 (40%), Positives = 24/42 (57%)
 Frame = +2

Query: 809 SFSGGSLDIGVLWTLHMIELVSTFAGDAWYGFHQFTPLLECT 934
           SF  G+LD+ +LWT  ++ L +T   + W GF Q    LE T
Sbjct: 427 SFLAGALDLQILWTGTLLALQNT-TWNGWQGFTQSPGSLETT 467


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 287,528,957
Number of extensions: 6401853
Number of successful extensions: 15040
Number of sequences better than 10.0: 26
Number of HSP's gapped: 14983
Number of HSP's successfully gapped: 28
Length of query: 575
Length of database: 100,686,439
Length adjustment: 119
Effective length of query: 456
Effective length of database: 68,045,334
Effective search space: 31028672304
Effective search space used: 31028672304
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)