ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | FLbaf32c17 |
|---|---|
| Clone Library Name | barley_pub |
>Q9M8D3:PUR4_ARATH Probable phosphoribosylformylglycinamidine synthase, chloroplast| precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 1387 Score = 866 bits (2238), Expect = 0.0 Identities = 420/582 (72%), Positives = 480/582 (82%), Gaps = 1/582 (0%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQLGIAIDGGKDS 182 EALTNLVWAKVT+L+DVKASGNWMYAAK++GEG I+LGIAIDGGKDS Sbjct: 806 EALTNLVWAKVTALSDVKASGNWMYAAKLEGEGSAMYDAAIALSEAMIELGIAIDGGKDS 865 Query: 183 LSMAAQCDGELVKAPGNLVISAYVTCPDITLTVTPDLKLG-KDGVLLHVDLAKGKRRLGC 359 LSMAA DGE+VKAPGNLVISAYVTCPDIT TVTPDLKLG DG+LLHVDLAKGKRRLG Sbjct: 866 LSMAAHADGEVVKAPGNLVISAYVTCPDITKTVTPDLKLGGDDGILLHVDLAKGKRRLGG 925 Query: 360 SALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFA 539 SALAQ F QIGNDCPD++DVPYLK VF+ VQ L++E L+SAGHDISDGGL+VT LEMAFA Sbjct: 926 SALAQVFGQIGNDCPDLDDVPYLKNVFDGVQALIAENLVSAGHDISDGGLVVTALEMAFA 985 Query: 540 GNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAP 719 GN G+NL++ L +TLF+EELGLV+E+ +LD V +KL A V+A +IG VT +P Sbjct: 986 GNKGINLDLASNGISLFETLFSEELGLVLEISKTNLDAVMEKLRAFDVTAEIIGNVTDSP 1045 Query: 720 EIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPLWHLSFT 899 IE+ VDG L E+TS LRD+WE+TSFQLE+LQRL SCV++EKEGLK R P W LSF Sbjct: 1046 LIEVKVDGITHLSEKTSFLRDMWEDTSFQLEKLQRLASCVEMEKEGLKFRHEPNWKLSFI 1105 Query: 900 PKFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEF 1079 P T+ +S PKVA+IREEGSN DREMSAAF+AAGFEPWD+T+SDLL +L +F Sbjct: 1106 PSSTNNNYMSQGMIPKVAVIREEGSNGDREMSAAFYAAGFEPWDVTVSDLLAGDITLDQF 1165 Query: 1080 RGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLG 1259 RGI FVGGFSYADVLDSAKGWAASIRFN+P++ QFQEFY RPDTFSLG+CNGCQLMALLG Sbjct: 1166 RGIVFVGGFSYADVLDSAKGWAASIRFNEPVLSQFQEFYKRPDTFSLGICNGCQLMALLG 1225 Query: 1260 WVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSA 1439 WVPGP +GGSL D SQPRF HNESGRFECRF SV I DSPSIM KGMEGSTLG+W+A Sbjct: 1226 WVPGPQVGGSL----DTSQPRFVHNESGRFECRFTSVTIKDSPSIMLKGMEGSTLGVWAA 1281 Query: 1440 HGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHL 1619 HGEGRA+FPD VL ++ S+LAPLRYCDD NVTE YPFN NGSPLGIAA+CSP+GRHL Sbjct: 1282 HGEGRAYFPDEGVLDHMLHSDLAPLRYCDDDGNVTEAYPFNLNGSPLGIAAICSPDGRHL 1341 Query: 1620 ALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 A+MPHPER F+MWQ+PWYP W VEK+GPSPWL+MFQNAR+W Sbjct: 1342 AMMPHPERCFLMWQFPWYPTSWDVEKAGPSPWLKMFQNARDW 1383
>O15067:PUR4_HUMAN Phosphoribosylformylglycinamidine synthase - Homo sapiens (Human)| Length = 1338 Score = 559 bits (1441), Expect = e-158 Identities = 300/590 (50%), Positives = 379/590 (64%), Gaps = 9/590 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQLGIAIDGGKDS 182 EALTNLV+A VT L DVK SGNWM+AAK+ GEG LG+A+DGGKDS Sbjct: 746 EALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAALADACEAMVAVMAALGVAVDGGKDS 805 Query: 183 LSMAAQCDGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKD-GVLLHVDLAKGKRRLGC 359 LSMAA+ E V+APG+LVISAY CPDIT TVTPDLK + G LL+V L+ G+ RLG Sbjct: 806 LSMAARVGTETVRAPGSLVISAYAVCPDITATVTPDLKHPEGRGHLLYVALSPGQHRLGG 865 Query: 360 SALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFA 539 +ALAQ F Q+G PD++ L + F + Q LL +RL+ +GHD+SDGGL+ +LEMAFA Sbjct: 866 TALAQCFSQLGEHPPDLDLPENLVRAFSITQGLLKDRLLCSGHDVSDGGLVTCLLEMAFA 925 Query: 540 GNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEV-TAA 716 GNCG+ +++ + D+L LFAEE GLV+EV DL V ++ AG+ +G A Sbjct: 926 GNCGLQVDVPVPRVDVLSVLFAEEPGLVLEVQEPDLAQVLKRYRDAGLHCLELGHTGEAG 985 Query: 717 PE--IELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPLWHL 890 P + + V+G V L+E +LR LWEETSFQL+ LQ CV E+ GL+ R P + L Sbjct: 986 PHAMVRVSVNGAVVLEEPVGELRALWEETSFQLDRLQAEPRCVAEEERGLRERMGPSYCL 1045 Query: 891 SFTPKFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASL 1070 T P+VAI+REEGSN DREM+ AFH AGFE WD+TM DL + L Sbjct: 1046 PPTFPKASVPREPGGPSPRVAILREEGSNGDREMADAFHLAGFEVWDVTMQDLCSGAIGL 1105 Query: 1071 TEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMA 1250 FRG+AFVGGFSYADVL SAKGWAA++ F+ + + F RPDTFSLGVCNGCQL+A Sbjct: 1106 DTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPRAGAELRRFRKRPDTFSLGVCNGCQLLA 1165 Query: 1251 LLGWVPGPDIGGSLGAGGDMSQPR-----FTHNESGRFECRFISVAIGDSPSIMFKGMEG 1415 LLGWV G + G D SQP HN SGR+E R+ SV +G P++M +GMEG Sbjct: 1166 LLGWVGGDPNEDAAEMGPD-SQPARPGLLLRHNLSGRYESRWASVRVGPGPALMLRGMEG 1224 Query: 1416 STLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAAL 1595 + L +WSAHGEG F + + + LAPL + DD N TE YP NPNGSP G+A + Sbjct: 1225 AVLPVWSAHGEGYVAFSSPELQAQIEARGLAPLHWADDDGNPTEQYPLNPNGSPGGVAGI 1284 Query: 1596 CSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 CS +GRHLA+MPHPER+ WQ+ W P + + SPWL++ NAR W Sbjct: 1285 CSCDGRHLAVMPHPERAVRPWQWAWRPPPFDTLTT--SPWLQLSINARNW 1332
>P35421:PUR4_DROME Phosphoribosylformylglycinamidine synthase - Drosophila melanogaster| (Fruit fly) Length = 1354 Score = 485 bits (1248), Expect = e-136 Identities = 286/610 (46%), Positives = 364/610 (59%), Gaps = 28/610 (4%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQLGIAIDGGKDS 182 EAL+NLV+ K++ LADVK SGNWM+AAK+ GEG +L IAIDGGKDS Sbjct: 754 EALSNLVFVKISELADVKCSGNWMWAAKLPGEGARMFDACKELCQILEELHIAIDGGKDS 813 Query: 183 LSMAAQCDGELVKAPGNLVISAYVTCPDITLTVTPDLK---LGKDGVLLHVDLAKGKRRL 353 LSMAA+ GE +K+PG LVIS Y CPD+ L VTPDLK G LL ++L + RL Sbjct: 814 LSMAAKVGGETIKSPGTLVISTYAPCPDVRLKVTPDLKGPGAGSKTSLLWINL-ENSARL 872 Query: 354 GCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMA 533 G SALAQA+ Q G D P++ L K F V Q LL + LI AGHD+SDGGL+V +LEMA Sbjct: 873 GGSALAQAYAQQGKDTPNLTRSDVLGKAFAVTQSLLGDGLIQAGHDVSDGGLLVCVLEMA 932 Query: 534 FAGNCGVNLNI-----ELKDNDL---------LQTLFAEELGLVIEVHLDDLDVVKQKLH 671 G G+ +++ +LK+ D L LFAEE G V+EV DL+ V+ Sbjct: 933 IGGLSGLRVDLSEPLAKLKNFDKSVEKLNRPELAVLFAEECGWVVEVLDTDLERVRSTYE 992 Query: 672 AAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDLRDL--------WEETSFQLEELQRL 827 AGV +G +D V LK S+L D WE TS++LE+LQ Sbjct: 993 KAGVPNYYLGVTEGFG-----LDSRVVLKNGKSELLDQPLRVLYKKWERTSYELEKLQAN 1047 Query: 828 KSCVKLEKEGLKSRTSPLWHLSFTPKFTDKKL-LSASSKP-KVAIIREEGSNSDREMSAA 1001 C + E L+ R +P + P+ +L L SS P +VA++REEG NS+REM A Sbjct: 1048 PECAEAEYNSLEYRQAPQYR---GPQNVQAELTLKRSSAPVRVAVLREEGVNSEREMMAC 1104 Query: 1002 FHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQ 1181 A FE D+TMSDLL AS++++RG+ F GGFSYAD L SAKGWAA+I N L+ Q Sbjct: 1105 LLRANFEVHDVTMSDLLQGTASVSQYRGLIFPGGFSYADTLGSAKGWAANILHNPRLLPQ 1164 Query: 1182 FQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRF 1361 F+ F R D FSLG+CNGCQLM L+G+V +GA D++ HN+S RFECR+ Sbjct: 1165 FEAFKRRQDVFSLGICNGCQLMTLIGFVGSAK--SEVGADPDVA---LLHNKSQRFECRW 1219 Query: 1362 ISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNV 1541 +V I + SIM M+ LG W AHGEGR F D ++S + L L+Y DD Sbjct: 1220 ATVKIPSNRSIMLGSMKDLVLGCWVAHGEGRFAFRDEKLISHLQSEQLVTLQYVDDVGKP 1279 Query: 1542 TEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKS-GPSPWL 1718 TE+YP NPNGSP GIA LCS +GRHLALMPHPER M+Q+P+ P ++V + SPW Sbjct: 1280 TELYPLNPNGSPQGIAGLCSSDGRHLALMPHPERCSSMYQWPYVPSSFEVSPTQSESPWQ 1339 Query: 1719 RMFQNAREWC 1748 MF NA WC Sbjct: 1340 IMFNNAYNWC 1349
>Q19311:PUR4_CAEEL Probable phosphoribosylformylglycinamidine synthase - Caenorhabditis| elegans Length = 1343 Score = 461 bits (1186), Expect = e-129 Identities = 270/639 (42%), Positives = 371/639 (58%), Gaps = 57/639 (8%) Frame = +3 Query: 3 EALTNLVWAKVT-------------------SLADVKASGNWMYAAKIDGEGXXXXXXXX 125 E + NL+WA +T SL DVK SGNWM+AAK DGEG Sbjct: 721 ETIMNLIWAPITDLKVHFLIYFYSKFQKLLLSLKDVKMSGNWMWAAKCDGEGARLVDAVG 780 Query: 126 XXXXXXIQLGIAIDGGKDSLSMAAQCDGELVKAPGNLVISAYVTCPDITLTVTPDLKLGK 305 ++G AIDGGKDSLSMA GE+VK+PG LV+SAY C ++T V P LK Sbjct: 781 ALCRGLREIGCAIDGGKDSLSMAVTAHGEVVKSPGTLVLSAYAPCTNVTKVVNPSLKAVP 840 Query: 306 DGVLLHVDLAKG--KRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSER--- 470 +L + + K RLG SALAQ + QIG+DCPDIE+ + KVF +VQ+LL+ Sbjct: 841 GSKILWIKIGSSEEKMRLGGSALAQVYSQIGDDCPDIENFSEISKVFSIVQQLLNREELA 900 Query: 471 ------LISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDL--LQTLFAEELGLVI 626 +I AGHDISDGGL+ ILEMAFAGN ++++I+ + ++ + LFAEE G+++ Sbjct: 901 GPLRKPIILAGHDISDGGLLTAILEMAFAGNVSIDIDIKPPNQNIKPIDILFAEECGILL 960 Query: 627 EVHLDDLDVVKQKLHAAGVSANVIGEVTAA----PEIELLVDGEVRLKERTSDLRDLWEE 794 EV + + V AG+ IG+ +A +++ V+G + + E+ DLR+ WE Sbjct: 961 EV--SNPENVLHIFSEAGIKCQEIGKASAVFGPDAHVKIHVNGHLEINEKLVDLREEWEL 1018 Query: 795 TSFQLEELQRLKSCVKLEKEGLKSRTSPLWHLSF----TPKFTDKKLLSASSKPKVAIIR 962 +L E Q +K +E ++ + F P F + S+ P+VAIIR Sbjct: 1019 VGDRLGEFQTNPKSLKEAREVRRTCQKINYKCDFDWYYNPAFIHNEQYF-STAPRVAIIR 1077 Query: 963 EEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGW 1142 EEGSN DREM++AF AGF+ +D+TM+D+L +L +RG+AFVGGFSYADVL SAKGW Sbjct: 1078 EEGSNGDREMASAFTLAGFQTFDVTMTDILAGH-TLEAYRGVAFVGGFSYADVLGSAKGW 1136 Query: 1143 AASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDMSQPR 1322 AA ++FN+ + +QF+ F +RPDTFS GVCNGCQLMA LGW+ GD Q Sbjct: 1137 AAGVQFNESVSKQFEAFRSRPDTFSYGVCNGCQLMAQLGWI------------GDEEQKG 1184 Query: 1323 FT----HNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDV 1490 T NE GRF+ F V I + SIM GME S LG+WS+HGEGR + + ++ Sbjct: 1185 PTVFLDENECGRFDSSFGPVKIEKNVSIMLSGMENSVLGLWSSHGEGRFTYRNLQNFQNL 1244 Query: 1491 VKSNLAPLRYCDDA-------NNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSF 1649 + +R+CDD +V YP+NPNGS +AA+CS +GRHLA+MPH +RSF Sbjct: 1245 KTNGQVCIRFCDDRGMTGADHGSVKLPYPWNPNGSIDDVAAICSRDGRHLAMMPHADRSF 1304 Query: 1650 MMWQY------PWYPKDWQVEKSGPSPWLRMFQNAREWC 1748 + WQ+ PW + + + SPW++MF+NA WC Sbjct: 1305 LTWQWAESSEVPWNAR-FDQKTVALSPWIKMFRNAYNWC 1342
>Q5E749:PUR4_VIBF1 Phosphoribosylformylglycinamidine synthase - Vibrio fischeri (strain| ATCC 700601 / ES114) Length = 1303 Score = 409 bits (1052), Expect = e-113 Identities = 244/598 (40%), Positives = 334/598 (55%), Gaps = 18/598 (3%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EA+TN+ + + +K S NWM A GE LG+ I GKD Sbjct: 719 EAITNIAATNIGDIKHIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 778 Query: 180 SLSMAAQCD--GEL--VKAPGNLVISAYVTCPDITLTVTPDLK-------LGKDGVLLHV 326 S+SM + + GE V +P +LVI+A+ D+ T+TP L+ LG ++L + Sbjct: 779 SMSMKTKWEENGEQKEVTSPLSLVITAFARVEDVRKTITPQLRTPDNLEGLGDTSLVL-I 837 Query: 327 DLAKGKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGG 506 DL GK RLG +ALAQ + Q+G+ D+++ LK +E VQ L++ + A HD DGG Sbjct: 838 DLGNGKNRLGATALAQVYKQLGDKPADVDNAAQLKGFYEGVQALVANDQVVAYHDKGDGG 897 Query: 507 LIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS 686 L VT+ EMAFAG+CGVN NIE D L LF EELG VI+V DDLD V L A G+ Sbjct: 898 LFVTLAEMAFAGHCGVNANIEALGEDTLAALFNEELGAVIQVRNDDLDAVLSTLAANGLE 957 Query: 687 A--NVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGL 860 A +VIG V A+ E+ + V ++ ++LR +W ET+ +++ L+ +C E E Sbjct: 958 ACSHVIGSVEASDELVIKSGESVVIERNRTELRTIWAETTHKMQGLRDNPACADQEHEAK 1017 Query: 861 KSRTSPLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWD 1031 K + P ++ + + ++ +KPK+AI+RE+G NS EM+AAF AGFE D Sbjct: 1018 KDNSDPGLNVKLSFDVNEDIAAPFINTGAKPKMAILREQGVNSHVEMAAAFDRAGFEATD 1077 Query: 1032 ITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDT 1211 I MSD+L +A L E+ G+ GGFSY DVL + +GWA S+ FN QF+ F+ R DT Sbjct: 1078 IHMSDILTGQAVLEEYNGLVACGGFSYGDVLGAGEGWAKSVLFNDSTRDQFENFFKREDT 1137 Query: 1212 FSLGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSP 1388 FSLGVCNGCQ+++ L +PG + PRF NES RFE RF V + S Sbjct: 1138 FSLGVCNGCQMLSNLRDLIPGAEY-----------WPRFVRNESERFEARFSLVEVQKSD 1186 Query: 1389 SIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPN 1568 S+ F GMEGS + I +HGEGR D + L+ + S LRY D+ N T+ YP NPN Sbjct: 1187 SVFFNGMEGSRMPIAVSHGEGRVEVRDNDHLNAIENSGTVALRYVDNHGNPTQQYPNNPN 1246 Query: 1569 GSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 GSP I L + +GR +MPHPER F W P+ W W+RMFQNAR+ Sbjct: 1247 GSPNAITGLTTTDGRVTIMMPHPERVFRTVANSWSPEGW----GENGAWMRMFQNARK 1300
>Q15R69:PUR4_PSEA6 Phosphoribosylformylglycinamidine synthase - Pseudoalteromonas| atlantica (strain T6c / BAA-1087) Length = 1295 Score = 408 bits (1048), Expect = e-113 Identities = 237/590 (40%), Positives = 331/590 (56%), Gaps = 11/590 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ A + L +K S NWM AA GE LG+ I GKD Sbjct: 717 EALTNIAAADIGDLKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAAQCDG----ELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM Q + V +P +LVI+A+ D+ T+TP+L D L+ +DL G+ Sbjct: 777 SMSMKTQWQDAQGDKAVTSPMSLVITAFGAVKDVRKTLTPELTTKGDTCLMLIDLGAGQN 836 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 R+G S LAQ + Q+G+ PD++ LK F +Q+L++E+ + A HD SDGGL T++E Sbjct: 837 RMGASCLAQVYQQLGDKTPDVDSPELLKGFFLAIQQLVNEKALHAYHDRSDGGLFTTLVE 896 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAGN G+++ ++ D LF EELG VI+ D L+ V L A G+S ++VIG Sbjct: 897 MAFAGNTGLDIKLDALTGDNASALFNEELGAVIQFDADKLNQVDAILAANGLSGVSHVIG 956 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 ++ +I +GE L+ R+ W +T+ ++ L+ C + E +P Sbjct: 957 TLSDDDQIRFSREGEPVLQNSRGVYRNAWAQTTHHMQRLRDNPECAEQELASKNDLNNPG 1016 Query: 882 WHLSFTPKFTD---KKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 H + + T+ ++ PK+AI+RE+G NS EM+AAF AGF D+ MSD+L Sbjct: 1017 LHAALSFDVTEDVAAPYIAKGIAPKMAILREQGVNSHVEMAAAFDRAGFASVDVHMSDIL 1076 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + SL+EF+G+ GGFSY DVL + +GWA SI FN +F F+ R +TFSLGVCN Sbjct: 1077 AGRVSLSEFQGLVACGGFSYGDVLGAGEGWAKSILFNAMARDEFSAFFERNETFSLGVCN 1136 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+++ L +PG + P F N+S RFE R + + DSPSI FKGM Sbjct: 1137 GCQMLSNLKSLIPGAE-----------HWPHFVTNQSERFEARVAMLEVKDSPSIFFKGM 1185 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 +GS + I +HGEGRA F L + SN L+Y D+ VTE YP NPNGSP GI+ Sbjct: 1186 QGSKMPIAVSHGEGRAEFAQTTGLEAALDSNTIALQYVDNYGKVTEQYPANPNGSPAGIS 1245 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 L S +GR +MPHPER F W+P DWQ + SPW+RMF+NAR Sbjct: 1246 GLTSKDGRATIMMPHPERVFRTVANSWHPDDWQED----SPWMRMFRNAR 1291
>Q8XYN6:PUR4_RALSO Phosphoribosylformylglycinamidine synthase - Ralstonia solanacearum| (Pseudomonas solanacearum) Length = 1369 Score = 407 bits (1046), Expect = e-113 Identities = 249/620 (40%), Positives = 342/620 (55%), Gaps = 40/620 (6%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EA+TN+ A + SLA +K S NWM A +DGE LGI+I GKD Sbjct: 761 EAITNIAAAPIASLAQLKLSANWMAACGVDGEDARLYDTVKAVGMELCPALGISIPVGKD 820 Query: 180 SLSMAAQCD--GEL--VKAPGNLVISAYVTCPDITLTVTPDLKL------GKDGVLLHVD 329 SLSM + D GE V AP +L++SA+ D+ T+TP LK D L+ +D Sbjct: 821 SLSMRTKWDDAGEAKEVVAPVSLIVSAFAPVTDVRKTLTPQLKPVASAGEAADTTLIVID 880 Query: 330 LAKGKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGL 509 L GK RLG S LAQ QIGN PD+ D LK+ F +Q+L + ++ A HD SDGGL Sbjct: 881 LGHGKHRLGGSILAQVTQQIGNSVPDVGDAEDLKRFFAAIQQLNAAGMLLAYHDRSDGGL 940 Query: 510 IVTILEMAFAGNCGVNLNIELKDND------------------------LLQTLFAEELG 617 T+ EMAFAG+CGV++N+++ D L+ LFAEELG Sbjct: 941 WATVCEMAFAGHCGVSINVDMLTLDGAHASDYGDAKNWAQQVSGRRADMTLRALFAEELG 1000 Query: 618 LVIEVHLDDLDVVKQKLHAAGVSA--NVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWE 791 VI+V D V L G++A +VIG A+ +IE+ D + +L+ W Sbjct: 1001 AVIQVPAAQRDAVFAVLREHGLAACSHVIGAPNASGQIEIWRDAKKVFSAPRIELQRAWT 1060 Query: 792 ETSFQLEELQRLKSCVKLEKEGLKSRTSPLWHLSFTPKFTDK---KLLSASSKPKVAIIR 962 + S+++ L+ C + E + L P + T + ++ ++P++AI+R Sbjct: 1061 DVSWRIASLRDNPECTQSEYDRLLDAEDPGISPNLTFDLAEDVAAPFIATGARPRMAILR 1120 Query: 963 EEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGW 1142 E+G NS EM+ A AGF+ +D+ MSDLL + L +F+G GGFSY DVL + +GW Sbjct: 1121 EQGVNSQVEMAYAMDKAGFDAYDVHMSDLLAGRTRLADFKGFVACGGFSYGDVLGAGEGW 1180 Query: 1143 AASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDMSQPR 1322 A +I FN L +QF F+NR D+ +LGVCNGCQ+MA L P I GAG + P+ Sbjct: 1181 AKTILFNGMLAEQFAAFFNRADSIALGVCNGCQMMANL----APIIP---GAG---AWPK 1230 Query: 1323 FTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSN 1502 FT N+S ++E R ++V + SPSI + GMEGS + I AHGEG A F + V Sbjct: 1231 FTRNQSEQYEGRLVTVQVEASPSIFYAGMEGSRIPIVVAHGEGYADFSQQGDIGKVA--- 1287 Query: 1503 LAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKD 1682 LRY D+ VT+ YP NPNGSP GIA++ + +GR LMPHPER F Q W+PKD Sbjct: 1288 -VGLRYVDNRGEVTQTYPLNPNGSPQGIASVTTHDGRFTVLMPHPERVFRAVQMSWHPKD 1346 Query: 1683 WQVEKSGPSPWLRMFQNARE 1742 W G SPW+RMF+NAR+ Sbjct: 1347 WAAAGDGSSPWMRMFRNARK 1366
>Q87RW0:PUR4_VIBPA Phosphoribosylformylglycinamidine synthase - Vibrio parahaemolyticus| Length = 1302 Score = 404 bits (1039), Expect = e-112 Identities = 244/597 (40%), Positives = 331/597 (55%), Gaps = 17/597 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 E+LTN+ + + +K S NWM A GE LG+ I GKD Sbjct: 718 ESLTNIAATDIGDIKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 777 Query: 180 SLSMAAQCD----GELVKAPGNLVISAYVTCPDITLTVTPDLKLGK------DGVLLHVD 329 S+SM + + + V +P +LVI+A+ D+ TVTP L+ D L+ VD Sbjct: 778 SMSMKTKWEENGESKEVTSPLSLVITAFGRVEDVRKTVTPQLRTSDTLEGLGDTSLVLVD 837 Query: 330 LAKGKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGL 509 L GK RLG +ALAQ + Q+G+ D+++ LK F+ +Q L+ + A HD DGGL Sbjct: 838 LGNGKNRLGATALAQVYKQLGDKPADVDNAEQLKGFFDAMQNLVRNDKLLAYHDKGDGGL 897 Query: 510 IVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSA 689 VT+ EMAFAG+CGV +I D L LF EELG V++V DDLD V L A G+ A Sbjct: 898 FVTLAEMAFAGHCGVKADIAELGEDALAVLFNEELGAVVQVKNDDLDSVLSTLAANGLEA 957 Query: 690 --NVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLK 863 +VIG V A+ + +V LK ++LR +W ET+ +++ L+ +C E E K Sbjct: 958 CSHVIGSVEASDDFVFTSGDDVVLKRSRTELRVIWAETTHKMQALRDNPACADQEFEAKK 1017 Query: 864 SRTSPLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDI 1034 T P ++S + + ++ +KPK+AI+RE+G NS EM+AAF AGFE DI Sbjct: 1018 DNTDPGLNVSLSFDVNEDIAAPYIAKGAKPKMAILREQGVNSHVEMAAAFDRAGFEATDI 1077 Query: 1035 TMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTF 1214 MSD+L +A L E++G+ GGFSY DVL + +GWA SI FN +QFQ F+NR +TF Sbjct: 1078 HMSDILTGQAVLDEYQGLVACGGFSYGDVLGAGEGWAKSILFNAQAREQFQAFFNREETF 1137 Query: 1215 SLGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPS 1391 SLGVCNGCQ+++ L +PG D+ PRF NES RFE RF V + S S Sbjct: 1138 SLGVCNGCQMLSNLKELIPGADL-----------WPRFVRNESERFEARFSLVEVQKSDS 1186 Query: 1392 IMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNG 1571 + F GM GS + I +HGEGR DG L+ + S LRY D+ N T+ YP NPNG Sbjct: 1187 VFFDGMAGSRMPIAVSHGEGRVEVRDGEHLNAIEASGTVALRYVDNNGNPTQQYPNNPNG 1246 Query: 1572 SPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 SP I L + +GR +MPHPER F W P+ W W+RMFQNAR+ Sbjct: 1247 SPNAITGLTTADGRVTIMMPHPERVFRTVANSWAPEGW----GENGAWMRMFQNARK 1299
>P74881:PUR4_SALTY Phosphoribosylformylglycinamidine synthase - Salmonella typhimurium| Length = 1294 Score = 404 bits (1039), Expect = e-112 Identities = 233/591 (39%), Positives = 334/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE QLG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLST-EDNALLLIDLGKGHN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L++ R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CGV ++I +D L LF EELG VI+V +D D V+ L G++ + +G Sbjct: 896 MAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEALLAQYGLADCVHYLG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + A + + + E + LR W ET++Q++ L+ C E E + T P Sbjct: 956 QALAGDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDTDPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L F + GGFSY DVL + +GWA SI FN + +F+ F++RP T +LGVCN Sbjct: 1076 GGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNHSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + NGR +MPHPER F W+P++W + SPW+R+F+NAR+ Sbjct: 1245 AVTTENGRVTIMMPHPERVFRTVANSWHPENWGED----SPWMRIFRNARK 1291
>Q7MN70:PUR4_VIBVY Phosphoribosylformylglycinamidine synthase - Vibrio vulnificus| (strain YJ016) Length = 1297 Score = 403 bits (1036), Expect = e-111 Identities = 239/592 (40%), Positives = 336/592 (56%), Gaps = 12/592 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 E+LTN+ + + +K S NWM A GE LG+ I GKD Sbjct: 718 ESLTNIAATDIGDIKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 777 Query: 180 SLSMAAQCD--GEL--VKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM + + GE V +P +L+I+A+ D+ T+TP L+ K + L+ VDL GK Sbjct: 778 SMSMKTKWNENGEEKEVTSPLSLIITAFARVEDVRKTITPQLRTDKGETSLVLVDLGNGK 837 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG +ALAQ + Q+G+ D+++ LK F+ +Q L+ + + A HD DGGL+VT+ Sbjct: 838 NRLGATALAQVYKQLGDKPADVDNAEQLKGFFDAMQALVRQDKLLAYHDKGDGGLLVTLA 897 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSA--NVI 698 EMAFAG+CGVN NI +D+L LF EELG V++V D+LD V L A G+ A +VI Sbjct: 898 EMAFAGHCGVNANIAALGDDVLAALFNEELGAVVQVKNDELDSVLSTLAANGLEACSHVI 957 Query: 699 GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP 878 G + A+ + V L+ +DLR +W ET+ +++ L+ +C E E K + P Sbjct: 958 GAIDASDNFVIRSGDVVVLERSRTDLRVIWAETTHKMQALRDNPACADQEFEAKKDNSDP 1017 Query: 879 LWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDL 1049 ++S + + + ++ +KPK+AI+RE+G NS EM+AAF AGFE DI MSD+ Sbjct: 1018 GLNVSLSYEVNEDIAAPYIAKGAKPKMAILREQGVNSHVEMAAAFDRAGFEATDIHMSDI 1077 Query: 1050 LNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVC 1229 L +A L E+ G+ GGFSY DVL + +GWA S+ FN +QFQ F+NR +TFSLGVC Sbjct: 1078 LTGQAVLDEYHGLVACGGFSYGDVLGAGEGWAKSVLFNAQAREQFQAFFNRENTFSLGVC 1137 Query: 1230 NGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKG 1406 NGCQ+++ L +PG D+ PRF NES RFE RF V + S S+ F G Sbjct: 1138 NGCQMLSNLKELIPGADL-----------WPRFVRNESERFEARFSLVEVQKSDSVFFDG 1186 Query: 1407 MEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGI 1586 M GS + I +HGEGR D L+ + S +R+ D+ N T+ YP NPNGSP I Sbjct: 1187 MAGSRMPIAVSHGEGRVEVRDAQHLAAIEASGTVAVRFVDNLGNPTQQYPNNPNGSPNAI 1246 Query: 1587 AALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 L + +GR +MPHPER F W P+ W W+RMFQNAR+ Sbjct: 1247 TGLTTKDGRVTIMMPHPERVFRTVANSWAPEGW----GENGAWMRMFQNARK 1294
>Q57LE6:PUR4_SALCH Phosphoribosylformylglycinamidine synthase - Salmonella choleraesuis| Length = 1294 Score = 403 bits (1035), Expect = e-111 Identities = 232/591 (39%), Positives = 333/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE QLG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLST-EDNALLLIDLGKGHN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L++ R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CGV ++I +D L LF EELG VI+V +D D V+ L G++ + +G Sbjct: 896 MAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEALLAQYGLADCVHYLG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + A + + + E + LR W ET++Q++ L+ C E E + P Sbjct: 956 QALAGDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDADPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDIAAPYIATGARPKVAVLREQGGNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L F + GGFSY DVL + +GWA SI FN + +F+ F++RP T +LGVCN Sbjct: 1076 GGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNPRVRDEFETFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNHSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + NGR +MPHPER F W+P++W + SPW+R+F+NAR+ Sbjct: 1245 AVTTENGRVTIMMPHPERVFRTVANSWHPENWGED----SPWMRIFRNARK 1291
>Q8DF81:PUR4_VIBVU Phosphoribosylformylglycinamidine synthase - Vibrio vulnificus| Length = 1297 Score = 402 bits (1034), Expect = e-111 Identities = 239/592 (40%), Positives = 335/592 (56%), Gaps = 12/592 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 E+LTN+ + + +K S NWM A GE LG+ I GKD Sbjct: 718 ESLTNIAATDIGDIKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 777 Query: 180 SLSMAAQCD--GEL--VKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM + + GE V +P +L+I+A+ D+ T+TP L+ K + L+ VDL GK Sbjct: 778 SMSMKTKWNENGEEKEVTSPLSLIITAFARVEDVRKTITPQLRTDKGETSLVLVDLGNGK 837 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG +ALAQ + Q+G+ D+++ LK F+ +Q L+ + + A HD DGGL+VT+ Sbjct: 838 NRLGATALAQVYKQLGDKPADVDNAEQLKGFFDAMQALVRQDKLLAYHDKGDGGLLVTLA 897 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSA--NVI 698 EMAFAG+CGVN NI +D+L LF EELG V++V D+LD V L A G+ A +VI Sbjct: 898 EMAFAGHCGVNANIAALGDDVLAALFNEELGAVVQVKNDELDSVLSTLAANGLEACSHVI 957 Query: 699 GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP 878 G + A+ + V L+ +DLR +W ET+ +++ L+ +C E E K + P Sbjct: 958 GAIDASDNFVIRSGDAVILERSRTDLRVIWAETTHKMQALRDNPACADQEFEAKKDNSDP 1017 Query: 879 LWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDL 1049 ++S + + ++ +KPK+AI+RE+G NS EM+AAF AGFE DI MSD+ Sbjct: 1018 GLNVSLSFDVNEDIAAPYIAKGAKPKMAILREQGVNSHVEMAAAFDRAGFEATDIHMSDI 1077 Query: 1050 LNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVC 1229 L +A L E+ G+ GGFSY DVL + +GWA S+ FN +QFQ F+NR +TFSLGVC Sbjct: 1078 LTGQAVLDEYHGLVACGGFSYGDVLGAGEGWAKSVLFNAQAREQFQAFFNRENTFSLGVC 1137 Query: 1230 NGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKG 1406 NGCQ+++ L +PG D+ PRF NES RFE RF V + S S+ F G Sbjct: 1138 NGCQMLSNLKELIPGADL-----------WPRFVRNESERFEARFSLVEVQKSDSVFFDG 1186 Query: 1407 MEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGI 1586 M GS + I +HGEGR D L+ + S +R+ D+ N T+ YP NPNGSP I Sbjct: 1187 MAGSRMPIAVSHGEGRVEVRDAQHLAAIEASGTVAVRFVDNLGNPTQQYPNNPNGSPNAI 1246 Query: 1587 AALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 L + +GR +MPHPER F W P+ W W+RMFQNAR+ Sbjct: 1247 TGLTTKDGRVTIMMPHPERVFRTVANSWAPEGW----GENGAWMRMFQNARK 1294
>Q31XT0:PUR4_SHIBS Phosphoribosylformylglycinamidine synthase - Shigella boydii serotype| 4 (strain Sb227) Length = 1294 Score = 402 bits (1034), Expect = e-111 Identities = 228/591 (38%), Positives = 332/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE LG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLST-EDNALLLIDLGKGNN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L+++R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CG+N +I +D L LF EELG VI+V D + V+ L G++ + +G Sbjct: 896 MAFAGHCGINADIASLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + + + +GE E + LR W ET++Q++ L+ C E + + P Sbjct: 956 QAVSGDRFVITANGETVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L +F + GGFSY DVL + +GWA SI FN + +F F++RP T +LGVCN Sbjct: 1076 TGRTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNTSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + +GR +MPHPER F W+P++W + PW+R+F+NAR+ Sbjct: 1245 AVTTESGRVTIMMPHPERVFRTVSNSWHPENWGED----GPWMRIFRNARK 1291
>Q3YYZ8:PUR4_SHISS Phosphoribosylformylglycinamidine synthase - Shigella sonnei (strain| Ss046) Length = 1294 Score = 401 bits (1031), Expect = e-111 Identities = 227/591 (38%), Positives = 332/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE LG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLST-EDNTLLLIDLGKGNN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L+++R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CG+N +I +D L LF EELG VI+V D + V+ L G++ + +G Sbjct: 896 MAFAGHCGINADIASLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + + + +G+ E + LR W ET++Q++ L+ C E + + P Sbjct: 956 QAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L +F + GGFSY DVL + +GWA SI FN + +F F++RP T +LGVCN Sbjct: 1076 TGRTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNTSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + +GR +MPHPER F W+P++W + PW+R+F+NAR+ Sbjct: 1245 AVTTESGRVTIMMPHPERVFRTVSNSWHPENWGED----GPWMRIFRNARK 1291
>Q8Z4L6:PUR4_SALTI Phosphoribosylformylglycinamidine synthase - Salmonella typhi| Length = 1294 Score = 401 bits (1031), Expect = e-111 Identities = 232/591 (39%), Positives = 332/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE QLG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLST-EDNALLLIDLGKGHN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L++ R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQVLVAARKLLAWHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CGV ++I +D L LF EELG VI+V +D D V+ L G++ + +G Sbjct: 896 MAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVETLLAQYGLADCVHYLG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + A + + E + LR W ET++Q++ L+ C E E + P Sbjct: 956 QALAGDRFVITANDRTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDADPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L F + GGFSY DVL + +GWA SI FN + +F+ F++RP T +LGVCN Sbjct: 1076 GGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNHSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + NGR +MPHPER F W+P++W + SPW+R+F+NAR+ Sbjct: 1245 AVTTENGRVTIMMPHPERVFRTVANSWHPENWGED----SPWMRIFRNARK 1291
>Q5PIG8:PUR4_SALPA Phosphoribosylformylglycinamidine synthase - Salmonella paratyphi-a| Length = 1294 Score = 400 bits (1029), Expect = e-111 Identities = 231/591 (39%), Positives = 333/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE QLG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLST-EDNALLLIDLGKGHN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L++ R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CGV ++I +D L LF EELG VI+V +D + V+ L G++ + +G Sbjct: 896 MAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDREAVEALLAQYGLADCVHYLG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + A + + + E + LR W ET++Q++ L+ C E E + P Sbjct: 956 QALAGDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDADPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L F + GGFSY DVL + +GWA SI FN + +F+ F++RP T +LGVCN Sbjct: 1076 GGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNPRVRDEFETFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNHSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + NGR +MPHPER F W+P++W + SPW+R+F+NAR+ Sbjct: 1245 AVTTENGRVTIMMPHPERVFRTVANSWHPENWGED----SPWMRIFRNARK 1291
>P15254:PUR4_ECOLI Phosphoribosylformylglycinamidine synthase - Escherichia coli| Length = 1294 Score = 400 bits (1027), Expect = e-110 Identities = 226/591 (38%), Positives = 332/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE LG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLST-EDNALLLIDLGKGNN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L+++R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CG++ +I +D L LF EELG VI+V D + V+ L G++ + +G Sbjct: 896 MAFAGHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + + + +G+ E + LR W ET++Q++ L+ C E + + P Sbjct: 956 QAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L +F + GGFSY DVL + +GWA SI FN + +F F++RP T +LGVCN Sbjct: 1076 TGRTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNTSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + +GR +MPHPER F W+P++W + PW+R+F+NAR+ Sbjct: 1245 AVTTESGRVTIMMPHPERVFRTVSNSWHPENWGED----GPWMRIFRNARK 1291
>Q32D15:PUR4_SHIDS Phosphoribosylformylglycinamidine synthase - Shigella dysenteriae| serotype 1 (strain Sd197) Length = 1294 Score = 399 bits (1025), Expect = e-110 Identities = 226/591 (38%), Positives = 332/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE LG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEEREMTSPLSLVISAFARLEDVRHTITPQLST-EDNALLLIDLGKGNN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L+++R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CG++ +I +D L LF EELG VI+V D + V+ L G++ + +G Sbjct: 896 MAFAGHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + + + +G+ E + LR W ET++Q++ L+ C E + + P Sbjct: 956 QAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L +F + GGFSY DVL + +GWA SI FN + +F F++RP T +LGVCN Sbjct: 1076 AGRTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNTSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + +GR +MPHPER F W+P++W + PW+R+F+NAR+ Sbjct: 1245 AVTTESGRVTIMMPHPERVFRTVSNSWHPENWGED----GPWMRIFRNARK 1291
>Q8XA46:PUR4_ECO57 Phosphoribosylformylglycinamidine synthase - Escherichia coli O157:H7| Length = 1294 Score = 399 bits (1025), Expect = e-110 Identities = 226/591 (38%), Positives = 332/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE LG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLST-EDNALLLIDLGKGNN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L+++R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CG++ +I +D L LF EELG VI+V D + V+ L G++ + +G Sbjct: 896 MAFAGHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + + + +G+ E + LR W ET++Q++ L+ C E + + P Sbjct: 956 QAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L +F + GGFSY DVL + +GWA SI FN + +F F++RP T +LGVCN Sbjct: 1076 AGRTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNTSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + +GR +MPHPER F W+P++W + PW+R+F+NAR+ Sbjct: 1245 AVTTESGRVTIMMPHPERVFRTVSNSWHPENWGED----GPWMRIFRNARK 1291
>Q0TET1:PUR4_ECOL5 Phosphoribosylformylglycinamidine synthase - Escherichia coli| O6:K15:H31 (strain 536 / UPEC) Length = 1294 Score = 399 bits (1024), Expect = e-110 Identities = 227/594 (38%), Positives = 333/594 (56%), Gaps = 14/594 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE LG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAA-------QCDGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAK 338 S+SM +C+ + +P +LVISA+ D+ T+TP L +D LL +DL K Sbjct: 777 SMSMKTRWQEGNEECE---MTSPLSLVISAFARVEDVRHTITPQLST-EDNALLLIDLGK 832 Query: 339 GKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVT 518 G LG +ALAQ + Q+G+ D+ DV LK ++ +Q L+++R + A HD SDGGL+VT Sbjct: 833 GNNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVT 892 Query: 519 ILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--AN 692 + EMAFAG+CG++ +I +D L LF+EELG VI+V D + V+ L G++ + Sbjct: 893 LAEMAFAGHCGIDADIATLGDDRLAALFSEELGAVIQVRAADREAVEAVLAQHGLADCVH 952 Query: 693 VIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRT 872 +G+ + + +G+ E + LR W ET++Q++ L+ C E + + Sbjct: 953 YVGQAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDA 1012 Query: 873 SPLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMS 1043 P ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MS Sbjct: 1013 DPGLNVKLSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMS 1072 Query: 1044 DLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLG 1223 DLL + L F + GGFSY DVL + +GWA SI FN + +F F++RP T +LG Sbjct: 1073 DLLAGRTGLEGFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALG 1132 Query: 1224 VCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMF 1400 VCNGCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ Sbjct: 1133 VCNGCQMMSNLRELIPGSEL-----------WPRFVRNTSDRFEARFSLVEVTQSPSLLL 1181 Query: 1401 KGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPL 1580 +GM GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP Sbjct: 1182 QGMVGSQMPIAVSHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPN 1241 Query: 1581 GIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 GI A+ + +GR +MPHPER F W+P++W + PW+R+F+NAR+ Sbjct: 1242 GITAVTTESGRVTIMMPHPERVFRTVSNSWHPENWGED----GPWMRIFRNARK 1291
>Q6D238:PUR4_ERWCT Phosphoribosylformylglycinamidine synthase - Erwinia carotovora| subsp. atroseptica (Pectobacterium atrosepticum) Length = 1294 Score = 397 bits (1021), Expect = e-110 Identities = 240/593 (40%), Positives = 328/593 (55%), Gaps = 14/593 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ + L VK S NWM AA GE LG+ I GKD Sbjct: 716 EALTNIAATHIGPLTRVKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPALGLTIPVGKD 775 Query: 180 SLSMAA--QCDGE--LVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM Q +GE V +P +LVISA+ D+ TVTP L+ G+D LL +DL G + Sbjct: 776 SMSMKTRWQEEGEDRAVTSPMSLVISAFARVEDVRNTVTPQLRTGQDNALLLIDLGAGNK 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G D+ L F +QEL++ + + A HD SDGGLIVT+ E Sbjct: 836 ALGATALAQVYRQLGRKTADVHSPEQLAGFFNAIQELVAAKALLAYHDRSDGGLIVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEV---HLDDLDVVKQKLHAAGVSANVI 698 MAFAG+CGV ++I + D L TLF EELG VI++ ++D + LH + + Sbjct: 896 MAFAGHCGVTVDIASQGEDTLATLFNEELGAVIQIPAARRAEVDAI-LALHGLADCVHYL 954 Query: 699 GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP 878 G+ + E +E S LR W ETS+Q++ L+ C E + P Sbjct: 955 GQAEEGTRFTINQGAEAVYQESRSTLRRWWAETSWQMQRLRDNPQCADQEHIARQDDNDP 1014 Query: 879 LWHLSFTPKFTDKKLLSA-----SSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMS 1043 ++S T F K+ ++A + +PKVA++RE+G NS EM+AAFH AGF+ DI MS Sbjct: 1015 GLNVSLT--FDPKEDIAAPYIAKNVRPKVAVLREQGVNSHVEMAAAFHRAGFDAIDIHMS 1072 Query: 1044 DLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLG 1223 DLL + +L +F+ + GGFSY DVL + +GWA SI FN + +F EF+ RP T +LG Sbjct: 1073 DLLANRRNLQDFQALVACGGFSYGDVLGAGEGWAKSILFNARVRDEFAEFFLRPQTLALG 1132 Query: 1224 VCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMF 1400 VCNGCQ+M+ L +PG D+ PRF N+S RFE RF V + SPS+ Sbjct: 1133 VCNGCQMMSNLRELIPGADL-----------WPRFVRNKSDRFEARFSLVEVDKSPSLFM 1181 Query: 1401 KGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPL 1580 M GS + I +HGEG+ D L+ + + L LRY + VTE YP NPNGS Sbjct: 1182 NDMAGSRMPIAVSHGEGQVEVRDDAHLAAIEEHGLVALRYINHYGQVTENYPANPNGSSN 1241 Query: 1581 GIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 GI A+ S +GR +MPHPER F W+P++W + PW+RMF+NAR Sbjct: 1242 GITAVTSTSGRATVMMPHPERVFRTVSNSWHPEEWGED----GPWMRMFRNAR 1290
>Q8FF26:PUR4_ECOL6 Phosphoribosylformylglycinamidine synthase - Escherichia coli O6| Length = 1294 Score = 397 bits (1021), Expect = e-110 Identities = 226/591 (38%), Positives = 332/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE LG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLST-EDNALLLIDLGKGNN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L+++R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CG++ +I +D L LF+EELG VI+V D + V+ L G++ + +G Sbjct: 896 MAFAGHCGIDADIATLGDDRLAALFSEELGAVIQVRAADREAVEAVLAQHGLADCVHYVG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + + + +G+ E + LR W ET++Q++ L+ C E + + P Sbjct: 956 QAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L F + GGFSY DVL + +GWA SI FN + +F F++RP T +LGVCN Sbjct: 1076 AGRTGLEGFHVLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNTSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + +GR +MPHPER F W+P++W + PW+R+F+NAR+ Sbjct: 1245 AVTTESGRVTIMMPHPERVFRTVSNSWHPENWGED----GPWMRIFRNARK 1291
>Q1R8H7:PUR4_ECOUT Phosphoribosylformylglycinamidine synthase - Escherichia coli (strain| UTI89 / UPEC) Length = 1294 Score = 396 bits (1018), Expect = e-109 Identities = 226/591 (38%), Positives = 331/591 (56%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ + +K S NWM AA GE LG+ I GKD Sbjct: 717 EALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + +P +LVISA+ D+ T+TP L +D LL +DL KG Sbjct: 777 SMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLST-EDNALLLIDLGKGNN 835 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G+ D+ DV LK ++ +Q L+++R + A HD SDGGL+VT+ E Sbjct: 836 ALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAE 895 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANVIG 701 MAFAG+CG++ +I +D L LF EELG VI+V D + V+ L G++ + +G Sbjct: 896 MAFAGHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHYVG 955 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + + + +G+ E + LR W ET++Q++ L+ C E + + P Sbjct: 956 QAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPG 1015 Query: 882 WHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ + + ++ ++PKVA++RE+G NS EM+AAFH AGF+ D+ MSDLL Sbjct: 1016 LNVKLSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLL 1075 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + L F + GGFSY DVL + +GWA SI FN + +F F++RP T +LGVCN Sbjct: 1076 AGRTGLEGFHVLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCN 1135 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N S RFE RF V + SPS++ +GM Sbjct: 1136 GCQMMSNLRELIPGSEL-----------WPRFVRNTSDRFEARFSLVEVTQSPSLLLQGM 1184 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEGR D L+ + L LRY D+ VTE YP NPNGSP GI Sbjct: 1185 VGSQMPIAVSHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGIT 1244 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + +GR +MPHPER F W+P++W + PW+R+F+NAR+ Sbjct: 1245 AVTTESGRVTIMMPHPERVFRTVSNSWHPENWGED----GPWMRIFRNARK 1291
>Q9HXN2:PUR4_PSEAE Phosphoribosylformylglycinamidine synthase - Pseudomonas aeruginosa| Length = 1298 Score = 395 bits (1016), Expect = e-109 Identities = 247/596 (41%), Positives = 328/596 (55%), Gaps = 15/596 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E +TNL A+V L+D+K S NWM AA GE +LGI I GKD Sbjct: 716 ETVTNLAAARVGKLSDIKLSANWMAAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKD 775 Query: 180 SLSMAA--QCDGE--LVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGV-LLHVDLAKGK 344 S+SM Q +GE V +P +L+++ + D+ ++TP L+L K L+ +DL +GK Sbjct: 776 SMSMKTRWQDNGEDKSVTSPVSLIVTGFAPVADVRQSLTPQLRLDKGETDLILIDLGRGK 835 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG S LAQ ++G PD++D LK F V+Q L ++ I A HD SDGGLI ++L Sbjct: 836 NRLGGSILAQVHGKLGRAVPDVDDAEDLKAFFAVIQGLNADGHILAYHDRSDGGLITSVL 895 Query: 525 EMAFAGNCGVNLNIE-LKDN--DLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--A 689 EMAFAG+CGV LN++ L D+ +L LF+EELG VI+V V + AAG+ Sbjct: 896 EMAFAGHCGVELNLDALADSREELAAVLFSEELGAVIQVREGATPEVLAQFSAAGLDDCV 955 Query: 690 NVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSR 869 VIG+ EI L +GE + L+ +W ETS+Q++ L+ C + E + L Sbjct: 956 AVIGQPVNGYEINLNYNGETVYSAQRRILQRIWSETSYQIQRLRDNADCAEQEFDALLDE 1015 Query: 870 TSPLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITM 1040 +P + + D + +PKVAI+RE+G N EM+AAF AGF D+ M Sbjct: 1016 DNPGLSIKLSYDVNDDIAAPYIKKGVRPKVAILREQGVNGQVEMAAAFDRAGFAAIDVHM 1075 Query: 1041 SDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSL 1220 SD+L + L F+G+ GGFSY DVL + +GWA SI FN FQ F+ R D+F+L Sbjct: 1076 SDILAGRVDLDAFKGLVACGGFSYGDVLGAGEGWAKSILFNARARDGFQAFFARKDSFAL 1135 Query: 1221 GVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIM 1397 GVCNGCQ+M+ L +PG + P F N S +FE R V + +S SI Sbjct: 1136 GVCNGCQMMSNLHELIPGTEF-----------WPHFVRNRSEQFEARVAMVQVQESSSIF 1184 Query: 1398 FKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSP 1577 +GM GS L I AHGEG A F L + S LR+ D+ VTE YP NPNGSP Sbjct: 1185 LQGMAGSRLPIAIAHGEGHAEFESEEALLEADLSGCVSLRFVDNHGKVTEAYPANPNGSP 1244 Query: 1578 LGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 GI L S +GR +MPHPER F Q W P DWQ E G WLRMF+NAR W Sbjct: 1245 RGITGLSSRDGRVTIMMPHPERVFRAVQNSWRPDDWQ-EDGG---WLRMFRNARVW 1296
>Q1H2I8:PUR4_METFK Phosphoribosylformylglycinamidine synthase - Methylobacillus| flagellatus (strain KT / ATCC 51484 / DSM 6875) Length = 1293 Score = 395 bits (1015), Expect = e-109 Identities = 237/593 (39%), Positives = 328/593 (55%), Gaps = 12/593 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 EA+TN+ + + +AD+K S NWM A GE QLGI+I GKD Sbjct: 715 EAITNIAASLIEDIADLKLSANWMAPAGHPGEDAALFDTVKAVGMELCPQLGISIPVGKD 774 Query: 180 SLSMAA----QCDGELVKAPGNLVISAYVTCPDITLTVTPDLK--LGKDGVLLHVDLAKG 341 S+SM + + + V AP +LV++A+ D T+TP L+ LG D LL +DL G Sbjct: 775 SMSMKTVWEERNEKKAVTAPISLVVTAFAPTADARKTLTPQLRTDLG-DTRLLLIDLGAG 833 Query: 342 KRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTI 521 + RLG SALAQ + +GN PD+ED LK F VQ+L E + A HD SDGGL T+ Sbjct: 834 RNRLGGSALAQVYGSVGNVAPDVEDADSLKHFFNAVQKLNREGRLLAYHDRSDGGLFATV 893 Query: 522 LEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAA-GVSANVI 698 +EMAFAG G+ L+I D + L+ EELG V++V DLD + +L +VI Sbjct: 894 VEMAFAGRTGLELDIASLGEDAVAVLYNEELGAVLQVRAADLDAITAELETTLRGKVHVI 953 Query: 699 GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP 878 G + +I + ++ E L W ET++Q+++L+ C + E + L Sbjct: 954 GAPASHGDIVIRQGTKLVFAESRVALHRAWSETTYQMQKLRDNPVCAQQEYDRLLDERDA 1013 Query: 879 LWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDL 1049 H T + +++ ++PK+AI+RE+G N EM+AAF AGF +D+ MSD+ Sbjct: 1014 GLHAKLTFDINENIAAPYIASGARPKMAILREQGVNGQVEMAAAFDRAGFNAFDVHMSDI 1073 Query: 1050 LNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVC 1229 ++ + SL +F G GGFSY DVL + +GWA SI FN +F F+NR D+F+LGVC Sbjct: 1074 ISGRVSLKDFAGFVACGGFSYGDVLGAGEGWAKSILFNPRARDEFTAFFNRTDSFALGVC 1133 Query: 1230 NGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKG 1406 NGCQ+M+ L +P GAG P F N S +FE R V + DSPS+ F G Sbjct: 1134 NGCQMMSNLHSIIP--------GAG---HWPHFVRNRSEQFEARVAMVEVLDSPSLFFNG 1182 Query: 1407 MEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGI 1586 M GS + I AHGEG A F D + L LRY D++ TEVYPFNPNGSP GI Sbjct: 1183 MAGSRMPIAVAHGEGYAEFADAAAQQRAQDARLVTLRYVDNSGLPTEVYPFNPNGSPQGI 1242 Query: 1587 AALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 L + +GR +MPHPER F Q+ W+P W + PW+RMF+NAR++ Sbjct: 1243 TGLTTADGRFSIMMPHPERVFRTVQHSWHPDGWGED----GPWIRMFRNARKF 1291
>Q7N1Z4:PUR4_PHOLL Phosphoribosylformylglycinamidine synthase - Photorhabdus luminescens| subsp. laumondii Length = 1295 Score = 394 bits (1013), Expect = e-109 Identities = 229/591 (38%), Positives = 328/591 (55%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ A + L +K S NWM AA GE LG+ I GKD Sbjct: 717 EALTNIASAYIQDLKRIKLSANWMSAAGHPGEDAGLYAAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAA----QCDGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM Q + + AP +LVI+A+ D+ TVTP+L +D LL +DL +GK Sbjct: 777 SMSMKTRWHDQGEEREMTAPLSLVITAFARVEDVRRTVTPELSTDEDNALLLIDLGQGKN 836 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + +GN D+ L F +Q+L++E+ + A HD SDGGL+VT+ E Sbjct: 837 TLGGTALAQVYRLLGNKTADVRSAEQLAGFFNAIQQLIAEQKLLAYHDRSDGGLLVTLAE 896 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKL--HAAGVSANVIG 701 MAFAG+CG+ +I + D D+L LF EELG V+++ D V+ L H + +G Sbjct: 897 MAFAGHCGIEADISVFDEDILAGLFTEELGAVVQIRASDRGFVESILAEHGLADCVHYLG 956 Query: 702 EVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPL 881 + A + + ++ S LR W ET++Q++ L+ +C E + + P Sbjct: 957 KAQAGDDFVIFSGNTEVYRQNRSTLRLWWAETTWQMQRLRDNPACADQEHQAKQDNQDPG 1016 Query: 882 WHLSFTPKFTD---KKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 ++ T ++ + +PKVA++RE+G NS EM+AAFH AGFE D+ MSDLL Sbjct: 1017 LNVKLTFDISEDIAAPYILQQVRPKVAVLREQGVNSHVEMAAAFHRAGFEAIDVHMSDLL 1076 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + + L++F+ + GGFSY DVL + +GWA SI FN+ + QF F+ RPDT +LGVCN Sbjct: 1077 SGRIGLSQFQTLVACGGFSYGDVLGAGEGWAKSILFNERVRDQFAVFFARPDTLALGVCN 1136 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG + PRF N S RFE RF V I DSPS+ + M Sbjct: 1137 GCQMMSNLRELIPGAE-----------HWPRFVRNRSERFEARFSLVEITDSPSLFLQDM 1185 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEG+ F + L + + L LRY ++ VTE YP NPNGS GI Sbjct: 1186 VGSRIPIAVSHGEGQVEFRNRQHLEMLESNQLVALRYVNNYGQVTENYPANPNGSVNGIT 1245 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ S +GR +MPHPER W+P +W+ + PW+R+F+NAR+ Sbjct: 1246 AVTSLDGRATVMMPHPERVSRTVNNSWHPDEWRED----GPWMRIFRNARK 1292
>Q9CLW4:PUR4_PASMU Phosphoribosylformylglycinamidine synthase - Pasteurella multocida| Length = 1297 Score = 393 bits (1010), Expect = e-108 Identities = 239/592 (40%), Positives = 329/592 (55%), Gaps = 13/592 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E++TN+ + + +K S NWM AA +GE QLG+ I GKD Sbjct: 718 ESITNIAATNIGDIKRIKLSANWMSAAGHEGEDAGLYQAVKAVGEELCPQLGLTIPVGKD 777 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKD-GVLLHVDLAKGK 344 S+SM + + V AP +LVISA+ D+ TVTP L+ K LL +DL +GK Sbjct: 778 SMSMKTTWHENGEQKTVTAPLSLVISAFARVEDVRKTVTPQLRTDKGHSRLLLIDLGEGK 837 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG +ALAQ + Q+G+ D+ +V LK F +Q L++E+ + A HD SDGGLI T+ Sbjct: 838 NRLGATALAQVYKQLGDKPADVVNVESLKNFFNAMQALVAEQKLLAYHDRSDGGLIATLA 897 Query: 525 EMAFAGNCGVNLNIE-LKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANV 695 EMAFAGNCG++++I L DNDL LF EELG VI+V DL V+ L G+ Sbjct: 898 EMAFAGNCGLSIHISALGDNDLA-VLFNEELGAVIQVRESDLSYVRDVLSQHGLIHLTKE 956 Query: 696 IGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTS 875 +GEVT IE+ ++ ++ S+LR +W E + Q++ L+ C E K + Sbjct: 957 LGEVTTEDRIEISRGTKLLFSQKRSELRGIWAELTHQMQRLRDNPECADQEFAAKKDPEN 1016 Query: 876 PLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSD 1046 + T + ++ KP++AI+RE+G NS EM+AAF AGFE D+ MSD Sbjct: 1017 KGFSAHLTYDINEDIAAPYIATGKKPRIAILREQGVNSHYEMAAAFDRAGFEAIDVHMSD 1076 Query: 1047 LLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGV 1226 L N + L +F + GGFSY DVL + GWA SI FN L QF EF+ P+T +LGV Sbjct: 1077 LHNARYRLKDFNALVACGGFSYGDVLGAGGGWAKSILFNPMLRDQFSEFFANPNTLTLGV 1136 Query: 1227 CNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFK 1403 CNGCQ+++ L +PG D + PRF N+S RFE R V I ++ S+ F+ Sbjct: 1137 CNGCQMVSNLAEIIPGTD-----------AWPRFVRNKSERFEARAALVRINETNSLWFQ 1185 Query: 1404 GMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLG 1583 GM GS + I +HGEGR F L + NL +Y D+ N TE+YP NPNGS G Sbjct: 1186 GMAGSHMPIAVSHGEGRVEFKHDQQLQMLKDQNLIVAQYIDNNLNPTEIYPANPNGSVEG 1245 Query: 1584 IAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 I AL + +GR +MPHPER F W+P+DW S W+R+F+NAR Sbjct: 1246 ITALSNQDGRVAIMMPHPERVFRTVSNSWHPEDW----SEDGAWMRLFRNAR 1293
>Q9KTN2:PUR4_VIBCH Phosphoribosylformylglycinamidine synthase - Vibrio cholerae| Length = 1297 Score = 392 bits (1007), Expect = e-108 Identities = 233/594 (39%), Positives = 332/594 (55%), Gaps = 13/594 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EA+TN+ + L +K S NWM A GE LGI I GKD Sbjct: 718 EAITNIAATDIGELKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGITIPVGKD 777 Query: 180 SLSMAA--QCDGEL--VKAPGNLVISAYVTCPDITLTVTPDLK--LGKDGVLLHVDLAKG 341 S+SM Q +GE V +P +L+I+A+ DI TVTP L+ LG+ ++L +DL G Sbjct: 778 SMSMKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGETSLIL-IDLGNG 836 Query: 342 KRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTI 521 + RLG +ALAQ + Q+G+ D+++ LK F+ VQ L+ + A HD DGGL+VT+ Sbjct: 837 QNRLGATALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRNDKLVAYHDKGDGGLLVTL 896 Query: 522 LEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSA--NV 695 EMAFAG+CG+ NIE +D L LF EELG V++V D+L+ V L A G+ A +V Sbjct: 897 AEMAFAGHCGIKANIETLGDDALAALFNEELGAVVQVKNDELNAVLATLAAHGLEACAHV 956 Query: 696 IGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTS 875 IGEV A+ + + EV ++ ++LR +W E + +++ L+ +C E + Sbjct: 957 IGEVEASDRLLITCGEEVLIERSRTELRTIWAEMTHKMQALRDNSACADQEFAAKQDNRD 1016 Query: 876 PLWHLSFTPKF---TDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSD 1046 P + T ++ +PK+AI+RE+G NS EM+AAF AGF+ D+ MSD Sbjct: 1017 PGLNAKLTYDVQADVAAPYIAKGVRPKMAILREQGVNSHVEMAAAFDRAGFDAVDVHMSD 1076 Query: 1047 LLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGV 1226 +L + L ++G+ GGFSY DVL + +GWA SI FN +QF++F+ R DTFSLGV Sbjct: 1077 ILTGQTVLDAYQGLVACGGFSYGDVLGAGEGWAKSILFNAQAREQFEQFFQRKDTFSLGV 1136 Query: 1227 CNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFK 1403 CNGCQ+++ L +PG ++ PRF NES RFE RF V + SPS+ F Sbjct: 1137 CNGCQMLSNLRDLIPGAEL-----------WPRFVRNESDRFEARFSLVEVQKSPSLFFS 1185 Query: 1404 GMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLG 1583 M GS + I +HGEGR D L+ + +S +R+ D+ T+ YP NPNGSP Sbjct: 1186 EMAGSRMPIAVSHGEGRVEVRDAQHLAAIEQSGTVAIRFVDNFGQPTQAYPSNPNGSPNA 1245 Query: 1584 IAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 I L + +GR +MPHPER F W+P +W W+RMFQNAR++ Sbjct: 1246 ITGLTTQDGRVTIMMPHPERVFRTVANSWHPDNW----GENGAWMRMFQNARKY 1295
>Q3IHZ2:PUR4_PSEHT Phosphoribosylformylglycinamidine synthase - Pseudoalteromonas| haloplanktis (strain TAC 125) Length = 1296 Score = 390 bits (1003), Expect = e-108 Identities = 228/594 (38%), Positives = 330/594 (55%), Gaps = 14/594 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 E+LTN+ A + SL ++K S NWM AA GE LG+ I GKD Sbjct: 715 ESLTNIACANIGSLENIKLSANWMAAAGHPGEDAGLYEAVKAIGEELCPALGLTIPVGKD 774 Query: 180 SLSMAAQCDGE------LVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAK 338 S+SM E V +P +L+I+A+ D+ TVTP L+ K + L+ VDL Sbjct: 775 SMSMKTTWKDEGDSQEKSVTSPLSLIITAFGRVDDVRKTVTPQLRTDKGETSLILVDLGA 834 Query: 339 GKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVT 518 GK R+G S+LAQ + Q+G+ PD++ LK + +Q L+++ + A HD SDGGL T Sbjct: 835 GKNRMGASSLAQVYKQLGDITPDVDSPELLKGFYNAMQVLVADSKLLAYHDRSDGGLFTT 894 Query: 519 ILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKL--HAAGVSAN 692 + EMAFAG+ GV ++I + ++ L+ EELG VI+V DLD V L H ++ Sbjct: 895 VAEMAFAGHTGVTVDINGLTGNDIEALYNEELGAVIQVANSDLDAVNAVLKDHGLATISH 954 Query: 693 VIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRT 872 +IG + + I L ++LR +W ET++Q++ + C K E + Sbjct: 955 IIGTLNSDDAIVFNRGKNTVLSNTRTELRTMWAETTYQMQARRDNPECAKQEFDAKFDVK 1014 Query: 873 SPLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMS 1043 P ++ + ++ +KP +AI+RE+G NS EM+AAF+ AGF D+ MS Sbjct: 1015 DPGLNVKLNFDLNEDIAAPYIATGAKPPMAILREQGVNSHLEMAAAFNRAGFAAIDVHMS 1074 Query: 1044 DLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLG 1223 D+L + SL +F+G+ GGFSY DVL + +GWA SI FN +QFQ F++R DTFSLG Sbjct: 1075 DILEGRLSLEQFKGLVACGGFSYGDVLGAGEGWAKSILFNDMAREQFQSFFHREDTFSLG 1134 Query: 1224 VCNGCQLMALL-GWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMF 1400 VCNGCQ+++ L +PG + PRF N+S RFE RF V I ++PS+ F Sbjct: 1135 VCNGCQMLSTLKELIPGTE-----------HWPRFVTNKSERFEARFSLVEIQENPSVFF 1183 Query: 1401 KGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPL 1580 GM GS + I +HGEG A F + N + + S +++ D+ N T YP NPNGSP Sbjct: 1184 NGMAGSRMPIAVSHGEGHAEFANDNAVKAALDSGTVAVKFVDNYGNPTTQYPANPNGSPE 1243 Query: 1581 GIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 GI + S +GR +MPHPER F W+P +W+ + SPW+RMF+NAR+ Sbjct: 1244 GITGITSTDGRATVMMPHPERVFRAVANSWHPDEWRED----SPWMRMFRNARK 1293
>Q0I5H4:PUR4_HAES1 Phosphoribosylformylglycinamidine synthase - Haemophilus somnus| (strain 129Pt) (Histophilus somni (strain 129Pt)) Length = 1297 Score = 390 bits (1003), Expect = e-108 Identities = 242/592 (40%), Positives = 323/592 (54%), Gaps = 13/592 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E++TN+ + + +K S NWM AA GE QLG+ I GKD Sbjct: 718 ESITNIAATDIGDIRRIKLSANWMAAAGHGGEDAGLYEAVKAIGEELCPQLGLTIPVGKD 777 Query: 180 SLSMAAQCDGE----LVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM E V AP +++ISA+ D+ TVTP L++ K D LL +DL +GK Sbjct: 778 SMSMKTTWQEEGYQKSVTAPLSVIISAFARVEDVRKTVTPQLRMDKGDSRLLLIDLGEGK 837 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG +ALAQ + Q+G+ D+ +V LK F +Q L+ + + A HD SDGGLIVT+ Sbjct: 838 NRLGATALAQVYKQLGDVPADVVNVSLLKGFFNAMQALVKQEKLLAYHDRSDGGLIVTLA 897 Query: 525 EMAFAGNCGVNLNIE-LKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANV 695 EMAFAG+CG++++I L DNDL LF EELG VI+V DL V+ L G+ Sbjct: 898 EMAFAGHCGISIDISALGDNDL-GVLFNEELGAVIQVKESDLKAVRAVLTEHGLIHLTKE 956 Query: 696 IGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTS 875 +G VTA IE+ V L E+ S LR +W E + Q++ L+ C E E K Sbjct: 957 LGIVTADDHIEITRSTRVLLSEKRSVLRGIWAELTHQMQRLRDNPDCADQEFEMKKDPND 1016 Query: 876 PLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSD 1046 T +K + +KP++AI+RE+G NS EM+AAF AGF D+ MSD Sbjct: 1017 KGLSAYLTYDLNEKITAPYIQKGTKPRIAILREQGVNSHYEMAAAFDRAGFNAIDVHMSD 1076 Query: 1047 LLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGV 1226 L + L +F + GGFSY DVL + GWA SI FN L QF F++R DT +LGV Sbjct: 1077 LQKGRHHLQDFNALVACGGFSYGDVLGAGGGWAKSILFNTALRDQFSAFFHRQDTLALGV 1136 Query: 1227 CNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFK 1403 CNGCQ+++ L +PG + G RF N+S RFE R V I ++ S+ F Sbjct: 1137 CNGCQMLSNLAEIIPGTENWG-----------RFVRNKSERFEARVAMVRINNTHSVWFD 1185 Query: 1404 GMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLG 1583 GM GS + I +HGEGR F L + NL +Y D N TE+YP NPNGS G Sbjct: 1186 GMAGSHMPIAVSHGEGRIEFKHDQQLQALKAQNLIAAQYIDSQLNPTEIYPANPNGSAEG 1245 Query: 1584 IAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 I AL + NGR +MPHPER F WYP++WQ + W+R+FQNAR Sbjct: 1246 ITALSNSNGRVAIMMPHPERVFRAVNNSWYPENWQED----GAWMRLFQNAR 1293
>Q2NS22:PUR4_SODGM Phosphoribosylformylglycinamidine synthase - Sodalis glossinidius| (strain morsitans) Length = 1295 Score = 389 bits (1000), Expect = e-107 Identities = 235/591 (39%), Positives = 329/591 (55%), Gaps = 11/591 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTNL + + VK S NWM AA GE LG+ I GKD Sbjct: 717 EALTNLAATHIGDIKRVKLSANWMAAAGHPGEDAGLYQAVKAVGEELCPALGLTIPVGKD 776 Query: 180 SLSMAAQ----CDGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + + + AP +LVI+A+ D+ TVTP L+ +D VLL +DL G Sbjct: 777 SMSMKTRWQHGAESREMTAPLSLVITAFARVEDVRATVTPQLQPARDNVLLLIDLGAGHH 836 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 LG +ALAQ + Q+G++ D+ D L F V+Q+L+++ + A HD +DGGL+VT+ E Sbjct: 837 ALGATALAQVYRQLGDETSDVRDAGQLAAFFRVMQQLVAQGWLLAYHDRADGGLLVTLAE 896 Query: 528 MAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEV 707 MAFAG+CG++ +I +D L LF EELG VI++ D D + H G++ + Sbjct: 897 MAFAGHCGIDADIGPLGDDALAALFNEELGAVIQIDEADRDAITALFHQEGLADCLHYLG 956 Query: 708 TAAP-EIELLVDGEVRL-KERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP- 878 TA P + +L GE L E + LR W ETS+Q++ L+ E + P Sbjct: 957 TAQPGDRFILRAGERSLYSESRTTLRTWWAETSWQMQRLRDNPESADQEHASRQDDNDPG 1016 Query: 879 -LWHLSFTPK-FTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 LSF PK ++ ++PKVA++RE+G NS EM+AAFH AGFE D+ MSDL Sbjct: 1017 LTVALSFDPKDDIAAPFIAKGARPKVAVLREQGVNSHVEMAAAFHRAGFEAIDVHMSDLF 1076 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 +L F + GGFSY DVL + +GWA S+ FN + +F+ F++RP T +LGVCN Sbjct: 1077 TGVQTLEGFHTLVACGGFSYGDVLGAGEGWAKSVLFNLRVRDEFEAFFHRPQTLALGVCN 1136 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+M+ L +PG ++ PRF N+S RFE RF V + S S++ +GM Sbjct: 1137 GCQMMSNLRELIPGAEL-----------WPRFVRNKSERFEARFSLVEVTQSQSLLLQGM 1185 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS L I +HGEGR D L+ + + L LRY D+ VTE YP NPNGSP GI Sbjct: 1186 VGSRLPIAVSHGEGRVEVRDAAHLAAIEHAGLVALRYVDNYGKVTENYPANPNGSPNGIT 1245 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 A+ + +GR MPHPER F + W+P +W + PW+R+F+NAR+ Sbjct: 1246 AVTNASGRVTLTMPHPERVFRTVSHSWHPAEWGED----GPWMRLFRNARK 1292
>Q1D9V4:PUR4_MYXXD Phosphoribosylformylglycinamidine synthase - Myxococcus xanthus| (strain DK 1622) Length = 1299 Score = 389 bits (998), Expect = e-107 Identities = 230/597 (38%), Positives = 326/597 (54%), Gaps = 16/597 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ A++ L+DVK S NWM AA GE LG+ I GKD Sbjct: 720 EALTNIAAARIGKLSDVKLSANWMAAAGSPGEDASLYAAVHAVGMELCPALGLTIPVGKD 779 Query: 180 SLSMAAQCDG----ELVKAPGNLVISAYVTCPDITLTVTPDL-KLGKDGVLLHVDLAKGK 344 S+SM + + V +P +L+ISA+ D+ ++TP L + D LL +DLA+GK Sbjct: 780 SMSMRTVWEEGGARKAVTSPVSLIISAFAPVLDVRKSLTPQLVDVADDTRLLFIDLARGK 839 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 +RLG S +A Q+G + PD+ED L+ F VQ L + A HD SDGGL T+ Sbjct: 840 QRLGGSVVAHVHGQVGPESPDVEDPALLRGFFAAVQALSESGSLLAYHDRSDGGLWATLC 899 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANV--I 698 EMAFAG CG+++++ D+ LF EELG V++V D+ V++ L G+S +V + Sbjct: 900 EMAFAGRCGLDVDLAPLGGDVTAALFNEELGAVVQVRASDVARVREVLAQHGLSRDVHEL 959 Query: 699 GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP 878 G A ++ + G+ + E T LR W S+++++L+ C E + P Sbjct: 960 GRPVTALQVRVRHGGDTLMAEDTLALRRTWSRVSYEMQKLRDNPICADQESAARSDASDP 1019 Query: 879 LWHLSFTPKFT-------DKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDIT 1037 +PK T ++ ++P+VA++RE+G NS +EM+AAF AGF D+ Sbjct: 1020 ----GLSPKLTFDPAQDVAAPFIAKGARPRVAVLREQGVNSQQEMAAAFTRAGFAAVDVH 1075 Query: 1038 MSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFS 1217 MSD+L+ + SL F+G+ GGFSY DVL + GWA SI FN F F+ RPD+F Sbjct: 1076 MSDILSGRVSLEGFKGVLACGGFSYGDVLGAGGGWAKSILFNPRARDAFAAFFARPDSFG 1135 Query: 1218 LGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSI 1394 LGVCNGCQ+M+ L +PG + PRF N S ++E R V + +PS+ Sbjct: 1136 LGVCNGCQMMSQLKDIIPGAE-----------HFPRFVRNASEQYEARLSLVEVSKTPSL 1184 Query: 1395 MFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGS 1574 ++GMEGS + I ++HGEGRA FP + V L R+ D+ V E YP NPNGS Sbjct: 1185 FYQGMEGSRMLIVTSHGEGRAEFPSVEDAARVNGLGLVTTRWVDNHGRVAESYPANPNGS 1244 Query: 1575 PLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 P GIA L + +GR MPHPER Q+ W P++W PW+RMF+NAR W Sbjct: 1245 PHGIAGLTTRDGRFTITMPHPERVHRSVQHSWRPREW----GDDGPWMRMFRNARVW 1297
>Q5QWY0:PUR4_IDILO Phosphoribosylformylglycinamidine synthase - Idiomarina loihiensis| Length = 1295 Score = 388 bits (997), Expect = e-107 Identities = 246/593 (41%), Positives = 327/593 (55%), Gaps = 13/593 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E+LTN+ A + L +K S NWM AA GE +LGI I GKD Sbjct: 716 ESLTNIAAADIGDLKRIKLSANWMCAAGHPGEDAGLYEAVKAVGEELCPELGITIPVGKD 775 Query: 180 SLSMAAQC--DGE--LVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM Q DGE V AP +LVI+A+ DI T+TP L+ K L+ +DL KG+ Sbjct: 776 SMSMKTQWQQDGEDKAVTAPMSLVITAFGRVNDIRSTLTPQLRTDKGQSHLVLIDLGKGQ 835 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG SALAQ + Q+G PD++D K F Q+L++E + A HD SDGGL T+ Sbjct: 836 NRLGGSALAQVYQQLGQHTPDLDDTETFKAFFNTTQQLVTEGRLLAYHDRSDGGLFTTVA 895 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANV--I 698 EMAFAGNCG + ++ D L TLF EELG VI+V + V AG+ V I Sbjct: 896 EMAFAGNCGAKVALDELGEDNLATLFNEELGAVIQVSDEQYQKVMDAYKTAGLGDCVKRI 955 Query: 699 GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP 878 GE T I D + L + + R +W ET+ ++ L+ C E+ LK R Sbjct: 956 GEPTHEDAIVFTRDEQNVLAQSRTHWRTVWAETTHHMQRLRDNPVCAD-EEFRLKQRADN 1014 Query: 879 ---LWHLSFTP-KFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSD 1046 L L+F P + ++ PKVAI+RE+G NS EM+AAF AGFE D+ MSD Sbjct: 1015 PGLLADLTFDPSEDIAAPYIAKGVAPKVAILREQGVNSHYEMAAAFDRAGFEAVDVHMSD 1074 Query: 1047 LLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGV 1226 +L + SL + + +A GGFSY DVL + +GWA SI FN +QF+ F+ R DT +LGV Sbjct: 1075 ILAGRVSLEDMQALAACGGFSYGDVLGAGEGWAKSILFNDRAREQFEAFFKRNDTLALGV 1134 Query: 1227 CNGCQLMALL-GWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFK 1403 CNGCQ+++ L +PG + PRF N S RFE RF V + +S SI Sbjct: 1135 CNGCQMLSTLKQLIPGTE-----------HWPRFVTNRSERFEARFSLVEVQESKSIFLG 1183 Query: 1404 GMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLG 1583 M GS + I +HGEGRA F + S + +++ LRY D+ V E YP NPNGSP G Sbjct: 1184 DMAGSRMPIAVSHGEGRAEFANPQQQSQLEQNSQVALRYIDNWGEVAEQYPANPNGSPKG 1243 Query: 1584 IAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 I A+ S +GR A+MPHPER F W+P +W + SPW+RMF+NAR+ Sbjct: 1244 ITAVTSDDGRVTAMMPHPERVFRTVANSWHPDEWGED----SPWMRMFRNARK 1292
>Q47XX7:PUR4_COLP3 Phosphoribosylformylglycinamidine synthase - Colwellia| psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) Length = 1320 Score = 388 bits (997), Expect = e-107 Identities = 238/606 (39%), Positives = 331/606 (54%), Gaps = 27/606 (4%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 E+LTN+ + L +K S NWM A GE LG+ I GKD Sbjct: 726 ESLTNIAGTDIGDLNRIKLSANWMSPAGHPGEDAGLYEAVKAIGEELCPALGLTIPVGKD 785 Query: 180 SLSMAAQCD--GEL--VKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM Q + GE V +P +LVI+A+ DI TVTP+L+ K D L+ +DL+KGK Sbjct: 786 SMSMKTQWEENGEQKSVTSPLSLVITAFGVVEDIRKTVTPELRTDKGDTRLVAIDLSKGK 845 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 +RLG S LAQ + Q+G++ PD++D LK F +Q L+ + A HDISDGGL T+ Sbjct: 846 KRLGGSCLAQVYKQLGSETPDVDDAEVLKGFFNAMQTLVRAEKVIAYHDISDGGLFTTVT 905 Query: 525 EMAFAGNCGVNLNIELKDN---DLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANV 695 EMAFAG+ GV+++I N D L TLF EELG VI++ D+D + L G+ N Sbjct: 906 EMAFAGHTGVDIDISKLSNGANDDLATLFNEELGGVIQIRESDVDAIHAILAQHGILENC 965 Query: 696 --IGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSR 869 IG + I DGEV L+ + R +W +T+++++ L+ C + E + Sbjct: 966 TDIGRLNNEDTIRFSRDGEVVLENSRTYYRTVWAQTTYRMQSLRDNPECAQQEHDVKFDT 1025 Query: 870 TSPLWHLSFTPKFTD---------------KKLLSASSKPKVAIIREEGSNSDREMSAAF 1004 P + T + + + + P+VAI+RE+G NS EM+AAF Sbjct: 1026 EDPGLNTELTFDINEDIVADLIIRDAVKDAENSANDITNPRVAILREQGVNSHVEMAAAF 1085 Query: 1005 HAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQF 1184 AGF D+ MSD+L+ +A L +F G+ GGFSY DVL + +GWA SI FN F Sbjct: 1086 DRAGFVAIDVHMSDILSGRADLADFNGLVACGGFSYGDVLGAGEGWAKSILFNANARTMF 1145 Query: 1185 QEFYNRPDTFSLGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRF 1361 + F+ R DTF+LGVCNGCQ+++ L +PG + P F N+S RFE RF Sbjct: 1146 KTFFEREDTFTLGVCNGCQMLSNLKDIIPGSE-----------HWPHFVQNKSERFEARF 1194 Query: 1362 ISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNV 1541 V I +SPS++FKGMEGS + I +HGEG A F + S +RY ++ +V Sbjct: 1195 SLVEIQESPSVLFKGMEGSRMPIAVSHGEGHAEFSSDAAIDAANNSGTVSMRYVNNYGDV 1254 Query: 1542 TEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLR 1721 TE YP NPNGS GI +L + +GR +MPHPER F W+P W + SPW+R Sbjct: 1255 TETYPANPNGSVDGITSLTTTDGRVTIMMPHPERVFRTVANSWHPDSWGED----SPWVR 1310 Query: 1722 MFQNAR 1739 MF+NAR Sbjct: 1311 MFRNAR 1316
>Q0HKU9:PUR4_SHESM Phosphoribosylformylglycinamidine synthase - Shewanella sp. (strain| MR-4) Length = 1293 Score = 387 bits (995), Expect = e-107 Identities = 232/590 (39%), Positives = 334/590 (56%), Gaps = 11/590 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E++ N+ A + S +K S NWM AA GE +L + I GKD Sbjct: 716 ESIMNIAGADIGSFKRIKLSANWMSAAGHPGEDAGLYEAVKAVGEELCPELSLTIPVGKD 775 Query: 180 SLSM--AAQCDG--ELVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM A Q DG + V AP +LVISA+ DI TVTP+L+ K + LL VDL GK Sbjct: 776 SMSMKTAWQQDGANKTVTAPMSLVISAFGVVQDIRNTVTPELRSDKGETSLLLVDLGAGK 835 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG S LAQ + ++G+ PD++D L+ FE +Q+L++++ + A HD SDGGL T++ Sbjct: 836 NRLGGSCLAQVYGELGDIAPDLDDAALLRGFFETMQKLVAKKSVIAYHDRSDGGLFTTLV 895 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGE 704 EMAFAGN G+++++ ++ LF EELG V++V D +++ + AGV ++IG Sbjct: 896 EMAFAGNTGLSIDLSALQGTDVERLFNEELGGVLQVSRADAELIAAQFAQAGVPCHMIGT 955 Query: 705 VTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPLW 884 + + + E LR LW ET+++++ L+ +C LE+ LK + L Sbjct: 956 LANDQRVTIKDGAREVFSETRVALRTLWSETTYRMQALRDNPACA-LEEFKLKQDETDLG 1014 Query: 885 ---HLSFTP-KFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 +LSF P + + + PK+AI+RE+G NS EM+AAF AGFE D+ MSD+L Sbjct: 1015 LTVNLSFDPSEDVAAPYILKGAAPKMAILREQGVNSHVEMAAAFDRAGFESLDVHMSDIL 1074 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + + SL EF+G+ GGFSY DVL + +GWA SI FN+ +F F+ R +F+LGVCN Sbjct: 1075 SGRISLEEFQGLVACGGFSYGDVLGAGEGWAKSILFNERARDEFSRFFERDSSFALGVCN 1134 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+++ L +PG + PRF N S RFE RF V + SPS+ F+GM Sbjct: 1135 GCQMLSNLKEIIPGSE-----------HWPRFVRNRSERFEARFSLVEVQQSPSLFFQGM 1183 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEG A F L+ S LR+ + + YP NPNGSP G+ Sbjct: 1184 AGSRMPIAVSHGEGHAEFASAQALALAEASGTIALRFVNGNGEIATQYPQNPNGSPNGLT 1243 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 +C+ +GR +MPHPER F W+P +W + SPW+RMF+NAR Sbjct: 1244 GICTTDGRVTLMMPHPERVFRTVANSWHPDNWGED----SPWMRMFRNAR 1289
>Q0HX47:PUR4_SHESR Phosphoribosylformylglycinamidine synthase - Shewanella sp. (strain| MR-7) Length = 1293 Score = 386 bits (992), Expect = e-106 Identities = 232/590 (39%), Positives = 333/590 (56%), Gaps = 11/590 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E++ N+ A + S +K S NWM AA GE +L + I GKD Sbjct: 716 ESIMNIAGADIGSFKRIKLSANWMSAAGHPGEDAGLYEAVKAVGEELCPELSLTIPVGKD 775 Query: 180 SLSM--AAQCDG--ELVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM A Q DG + V AP +LVISA+ DI TVTP+L+ K + LL VDL GK Sbjct: 776 SMSMKTAWQQDGANKTVTAPMSLVISAFGVVQDIRNTVTPELRSDKGETSLLLVDLGAGK 835 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG S LAQ + ++G+ PD++D L+ FE +Q+L++++ + A HD SDGGL T++ Sbjct: 836 NRLGGSCLAQVYGELGDIAPDLDDAALLRGFFETMQKLVAKKSVIAYHDRSDGGLFTTLV 895 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGE 704 EMAFAGN G+ +++ ++ LF EELG V++V D +++ + AGV ++IG Sbjct: 896 EMAFAGNTGLAIDLSALQGTDVERLFNEELGGVLQVSRADAELIAAQFAQAGVPCHMIGS 955 Query: 705 VTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPLW 884 + + + E LR LW ET+++++ L+ +C LE+ LK + L Sbjct: 956 LANDQRVTIKDGAREVFSETRVALRTLWSETTYRMQALRDNPACA-LEEFKLKQDKTDLG 1014 Query: 885 ---HLSFTP-KFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 +LSF P + + + PK+AI+RE+G NS EM+AAF AGFE D+ MSD+L Sbjct: 1015 LTVNLSFDPSEDVAAPYILKGAAPKMAILREQGVNSHVEMAAAFDRAGFESRDVHMSDIL 1074 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + + SL EF+G+ GGFSY DVL + +GWA SI FN+ +F F+ R +F+LGVCN Sbjct: 1075 SGRISLEEFQGLVACGGFSYGDVLGAGEGWAKSILFNERARDEFSRFFERDSSFALGVCN 1134 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+++ L +PG + PRF N S RFE RF V + SPS+ F+GM Sbjct: 1135 GCQMLSNLKEIIPGSE-----------HWPRFVRNRSERFEARFSLVEVQQSPSLFFQGM 1183 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEG A F L+ S LR+ + + YP NPNGSP G+ Sbjct: 1184 AGSRMPIAVSHGEGHAEFASAQALALAEASGTIALRFVNGNGEIATQYPQNPNGSPNGLT 1243 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 +C+ +GR +MPHPER F W+P +W + SPW+RMF+NAR Sbjct: 1244 GICTTDGRVTLMMPHPERVFRTVANSWHPDNWGED----SPWMRMFRNAR 1289
>Q6LU24:PUR4_PHOPR Phosphoribosylformylglycinamidine synthase - Photobacterium profundum| (Photobacterium sp. (strain SS9)) Length = 1322 Score = 386 bits (992), Expect = e-106 Identities = 240/616 (38%), Positives = 334/616 (54%), Gaps = 37/616 (6%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EA+TN+ A + + + S NWM A GE LG+ I GKD Sbjct: 718 EAITNIASADIGDMKRINLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKD 777 Query: 180 SLSMAAQC--DGEL--VKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM + DGE V +P +LVI+A+ D+ TVTP L+ K + L+ +DL G+ Sbjct: 778 SMSMKTKWEQDGEQKEVTSPLSLVITAFGRVEDVRKTVTPQLRTDKGESSLILIDLGCGQ 837 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG +ALAQ + Q+G+ D+++ LK F VQ L+ + + A HD DGGL VT+ Sbjct: 838 NRLGATALAQVYKQLGDKPADVDNPELLKGFFYAVQALVRDEKVLAYHDRGDGGLYVTLA 897 Query: 525 EMAFAGNCGVNLNIELKD----NDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSA- 689 EMAFAG+ GV ++I + +D+L LF EELG V++V +DLD VK L G++A Sbjct: 898 EMAFAGHTGVEVDINTSESDACDDVLAMLFNEELGAVLQVRTEDLDTVKSVLAEHGLTAC 957 Query: 690 -NVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKS 866 +VIG V + + + L++ +DLR +W ET++Q++ ++ + E E K Sbjct: 958 SHVIGTVVDEDVVRIWNGNDRVLEQSRTDLRTVWAETTYQMQAMRDNPAGALQEFEAKKD 1017 Query: 867 RTSPLWHLSFT--------------------PK----FTDKKLLSASSKPKVAIIREEGS 974 + P T PK + ++ +KP++AI+RE+G Sbjct: 1018 NSDPGLSAQLTFDINEDVAAPFIAAPFITKAPKTGASVVNAPAINLGAKPQMAILREQGV 1077 Query: 975 NSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASI 1154 NS EM+AAF AGFE D+ MSD+L+ L F G+ GGFSY DVL + +GWA S+ Sbjct: 1078 NSHVEMAAAFDRAGFEATDVHMSDILSGNVQLEGFNGLVACGGFSYGDVLGAGEGWAKSV 1137 Query: 1155 RFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLG-WVPGPDIGGSLGAGGDMSQPRFTH 1331 FN QF+ F+ R DTFSLGVCNGCQ+M+ L +PG D+ PRF Sbjct: 1138 LFNNIARDQFEAFFKRNDTFSLGVCNGCQMMSNLSELIPGSDL-----------WPRFVR 1186 Query: 1332 NESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAP 1511 NES RFE RF V + S S+ F M GS + I +HGEGR +G L+ + +S Sbjct: 1187 NESERFEARFSLVEVQKSDSLFFNEMAGSRMPIAVSHGEGRVEVRNGEHLNAIEQSGTVA 1246 Query: 1512 LRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQV 1691 LRY D+ NVT+ YP NPNGSP GI L + +GR +MPHPER F W+P DW Sbjct: 1247 LRYLDNFGNVTQNYPANPNGSPNGITGLTTMDGRVTIMMPHPERVFRTVANSWHPDDWNE 1306 Query: 1692 EKSGPSPWLRMFQNAR 1739 SPW+RMF+NAR Sbjct: 1307 N----SPWMRMFRNAR 1318
>Q65RJ7:PUR4_MANSM Phosphoribosylformylglycinamidine synthase - Mannheimia| succiniciproducens (strain MBEL55E) Length = 1297 Score = 386 bits (992), Expect = e-106 Identities = 236/592 (39%), Positives = 326/592 (55%), Gaps = 13/592 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 E++TN+ + + +K S NWM AA +GE LG+ + GKD Sbjct: 718 ESITNIAATNIGDIKRIKLSANWMSAAGHEGEDAGLYEAVKAVGEELCPALGLTVPVGKD 777 Query: 180 SLSM----AAQCDGELVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM + + + V AP +LVISA+ D+ TVTP L+ K + LL +DL +GK Sbjct: 778 SMSMKTTWSENGEQKTVTAPLSLVISAFARVEDVRKTVTPQLRTDKGETALLLIDLGEGK 837 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG +ALAQ + Q+G+ D+ +V LK + +Q L+ + + A HD SDGGLIVT+ Sbjct: 838 NRLGATALAQVYKQLGDKPADVVNVELLKGFYNAMQTLVQQGKLLAYHDRSDGGLIVTLA 897 Query: 525 EMAFAGNCGVNLNIE-LKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--ANV 695 EMAFAGNCG+ I L DNDL LF+EELG VI+V DL V++ L G+ Sbjct: 898 EMAFAGNCGIRAEISALGDNDL-GILFSEELGAVIQVRESDLAAVREVLTQHGLIHLTKD 956 Query: 696 IGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTS 875 +G VT E E+ +V L E+ S+LR +W E + Q++ L+ C E K + Sbjct: 957 LGLVTEYDEFEIKRGTKVVLSEKRSELRGIWAELTHQMQRLRDNPECADQEFAAKKDPAN 1016 Query: 876 PLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSD 1046 + T + ++ KP++A++RE+G NS EM AAF AGFE D+ MSD Sbjct: 1017 QGFSAHLTYDINEDVAAPYIATGKKPRIAVLREQGVNSHVEMGAAFDRAGFEAIDVHMSD 1076 Query: 1047 LLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGV 1226 L + +L +F + GGFSY DVL + GWA S+ FN L QFQ F+ R DT +LGV Sbjct: 1077 LHTARQNLKDFNALVACGGFSYGDVLGAGGGWAKSVLFNTALRDQFQAFFEREDTLALGV 1136 Query: 1227 CNGCQLMALLG-WVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFK 1403 CNGCQ+++ L +PG + + PRF N S RFE R V I +S S+ F+ Sbjct: 1137 CNGCQMISTLADIIPGTE-----------NWPRFVRNTSERFEARAALVRINESNSVWFQ 1185 Query: 1404 GMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLG 1583 GM GS + I +HGEGR F + + L + L +Y D+ TEVYP NPNGS G Sbjct: 1186 GMAGSHMPIAVSHGEGRVEFKNDSQLQGLRDQGLIIAQYVDNNIRPTEVYPANPNGSVDG 1245 Query: 1584 IAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 I AL + NGR +MPHPER F W+P+DW S W+R+F+NAR Sbjct: 1246 ITALSNTNGRVAIMMPHPERVFRTVSNSWHPEDW----SEDGAWMRLFRNAR 1293
>Q12PR7:PUR4_SHEDO Phosphoribosylformylglycinamidine synthase - Shewanella denitrificans| (strain OS217 / ATCC BAA-1090 / DSM 15013) Length = 1293 Score = 386 bits (991), Expect = e-106 Identities = 232/589 (39%), Positives = 326/589 (55%), Gaps = 10/589 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E++ N+ + S +K S NWM AA GE QL I I GKD Sbjct: 716 ESIMNIAGTDIGSFKRIKLSANWMSAAGHPGEDAGLYEAVKAVGEELCPQLEITIPVGKD 775 Query: 180 SLSMAAQCDG----ELVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM + + V +P +LVI+A+ DI TVTP+L+ K D LL +DL+ GK Sbjct: 776 SMSMKTAWEDNGVHKSVTSPMSLVITAFGVVQDIRNTVTPELRSDKGDTALLLLDLSHGK 835 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG S LAQ F +G+ PD++D LK FEV+Q L++++ I A HD SDGGL T+ Sbjct: 836 TRLGGSCLAQVFSSLGDVAPDLDDSTTLKGFFEVMQTLVADQSILAYHDRSDGGLFTTVT 895 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGE 704 EMAFAGN G +++ L LF EELG VI+V + + + AAGV+ + IG Sbjct: 896 EMAFAGNTGAEIDLSALQGSDLARLFNEELGAVIQVSQAQAEAITAQFIAAGVACHAIGG 955 Query: 705 VTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP-- 878 +T ++ + V +++ S+LR LW +TS++++ L+ C E +S T P Sbjct: 956 LTEHNKLVVKDGSRVVFQQQRSELRRLWSQTSYKMQALRDNPDCALEEFSLKQSETDPGL 1015 Query: 879 LWHLSFTP-KFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLN 1055 L+F P + + PK+AI+RE+G NS EM+AAF AGFE D+ MSD+L+ Sbjct: 1016 TVKLNFDPSQDVAAPYILKGIAPKMAILREQGVNSHVEMAAAFDRAGFESRDVHMSDILS 1075 Query: 1056 QKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNG 1235 + SL EF+G+ GGFSY DVL + +GWA SI FNQ +F F+ R +F+LGVCNG Sbjct: 1076 GRISLDEFQGLVACGGFSYGDVLGAGEGWAKSILFNQRARDEFSRFFERDLSFALGVCNG 1135 Query: 1236 CQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME 1412 CQ+++ L +PG + PRF N S RFE R V + SPS+ F+GM Sbjct: 1136 CQMLSNLKEIIPGSE-----------HWPRFVRNRSERFEARVSLVEVQQSPSLFFEGMA 1184 Query: 1413 GSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAA 1592 GS + I +HGEG A F ++ + LRY + YP NPNGSP G++ Sbjct: 1185 GSRMPIAVSHGEGLAEFASMQAMTAAESTGTVALRYVTGTGEIATQYPQNPNGSPNGLSG 1244 Query: 1593 LCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 +CS +G+ +MPHPER F W+P +W + SPW+RMF+NAR Sbjct: 1245 ICSTDGKVTIMMPHPERVFRTVANSWHPDNWGED----SPWMRMFRNAR 1289
>Q8EC57:PUR4_SHEON Phosphoribosylformylglycinamidine synthase - Shewanella oneidensis| Length = 1293 Score = 384 bits (987), Expect = e-106 Identities = 231/590 (39%), Positives = 334/590 (56%), Gaps = 11/590 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E++ N+ A + S +K S NWM AA GE +L + I GKD Sbjct: 716 ESIMNIAGADIGSFKRIKLSANWMSAAGHPGEDAGLYEAVKAVGEELCPELSLTIPVGKD 775 Query: 180 SLSM--AAQCDG--ELVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM A Q DG + V +P +LVI+A+ DI TVTP+L+ K + LL VDL G+ Sbjct: 776 SMSMKTAWQQDGVNKTVTSPMSLVITAFGVVQDIRNTVTPELRSDKGETSLLLVDLGAGQ 835 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG S LAQ + ++G+ PD++D L+ FE +Q+L++ +L+ A HD SDGGL T++ Sbjct: 836 NRLGGSCLAQVYGELGDVAPDLDDAALLRGFFETMQKLVANKLVIAYHDRSDGGLFTTLV 895 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGE 704 EMAFAGN G+++++E L+ LF EELG V++V D+ + + AGV +VIG Sbjct: 896 EMAFAGNIGLDIDVEDLQGTDLERLFNEELGAVLQVSRDNAAKIAAQFAIAGVPCHVIGT 955 Query: 705 VTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPLW 884 + I + + LR +W ET+++++ ++ +C LE+ LK + L Sbjct: 956 LADDQCITIKDGAREIFSDTRVALRTVWSETTYRMQAMRDNPACA-LEEFKLKQDETDLG 1014 Query: 885 ---HLSFTP-KFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL 1052 +LSF P + + + PK+AI+RE+G NS EM+AAF AGFE D+ MSD+L Sbjct: 1015 LTVNLSFDPSEDVAAPYILKGAAPKMAILREQGVNSHVEMAAAFDRAGFESRDVHMSDIL 1074 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 + + SL EF+G+ GGFSY DVL + +GWA SI FN+ +F F+ R +F+LGVCN Sbjct: 1075 SGRISLEEFQGLVACGGFSYGDVLGAGEGWAKSILFNERARNEFSRFFERDSSFALGVCN 1134 Query: 1233 GCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM 1409 GCQ+++ L +PG + PRF N S RFE RF V + SPS+ F+GM Sbjct: 1135 GCQMLSNLKEIIPGSE-----------HWPRFVRNRSERFEARFSLVEVQQSPSLFFQGM 1183 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 GS + I +HGEG A F L+ S LR+ + + YP NPNGSP G+ Sbjct: 1184 AGSRMPIAVSHGEGHAEFASAQALALAEASGTIALRFVNGKGEIATQYPQNPNGSPNGLT 1243 Query: 1590 ALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 +C+ +GR +MPHPER F W+P +W + SPW+RMF+NAR Sbjct: 1244 GICTTDGRVTLMMPHPERVFRTVANSWHPDNWGED----SPWMRMFRNAR 1289
>Q3KHL4:PUR4_PSEPF Phosphoribosylformylglycinamidine synthase - Pseudomonas fluorescens| (strain PfO-1) Length = 1298 Score = 384 bits (986), Expect = e-106 Identities = 225/598 (37%), Positives = 331/598 (55%), Gaps = 17/598 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E +TN+ +++ L+D+K S NWM AA GE +LGI I GKD Sbjct: 716 ETITNIAASRINKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKD 775 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGV-LLHVDLAKGK 344 S+SMA + + + V +P +L+++ + DI T+TP+L++ K L+ +DL +G+ Sbjct: 776 SMSMATRWNDNGEDKTVTSPMSLIVTGFAPVADIRQTLTPELRMDKGTTDLILIDLGRGQ 835 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 R+G S LAQ ++G PD++D LK F V+Q L ++ + A HD SDGGL+ +++ Sbjct: 836 NRMGASILAQVHGKLGKQAPDVDDAEDLKAFFAVIQGLNADGHLLAYHDRSDGGLLTSVM 895 Query: 525 EMAFAGNCGVNLNIEL---KDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--A 689 EMAFAG+CG++LN++ ++ LF EELG VI+V D + + AAG+ Sbjct: 896 EMAFAGHCGLSLNLDSVAESSAEIAAILFNEELGAVIQVRQDATPDILAQFSAAGLGDCV 955 Query: 690 NVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSR 869 +VIG+ +I + +G+ + + L+ W ETS+Q++ L+ C + E + L Sbjct: 956 SVIGQPINNGQINITFNGDTVFEGQRRLLQRQWAETSYQIQRLRDNADCAEQEFDALLEE 1015 Query: 870 TSPLWHLSFTPKFTDKKLLSA-----SSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDI 1034 +P LS + + ++A +P+VA++RE+G N EM+AAF AGF D+ Sbjct: 1016 DNP--GLSVKLSYDVNQDIAAPYIKKGIRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDV 1073 Query: 1035 TMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTF 1214 MSD+L + L EF+G+ GGFSY DVL + +GWA S FN FQ F+ R D+F Sbjct: 1074 HMSDILAGRVDLNEFKGLVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERNDSF 1133 Query: 1215 SLGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPS 1391 +LGVCNGCQ+M+ L +PG + P F N S +FE R V + +S S Sbjct: 1134 TLGVCNGCQMMSNLHELIPGSEF-----------WPHFVRNRSEQFEARVAMVQVQESNS 1182 Query: 1392 IMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNG 1571 I +GM GS + I AHGEG A F L + S +R+ D+ VTE YP NPNG Sbjct: 1183 IFLQGMAGSRMPIAIAHGEGHAEFESEEALLEADLSGCVAMRFVDNHGKVTEAYPANPNG 1242 Query: 1572 SPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 SP GI L S +GR +MPHPER F Q W +DW + +PW+RMF+NAR W Sbjct: 1243 SPRGITGLTSRDGRVTIMMPHPERVFRAVQNSWRSEDWNED----APWMRMFRNARVW 1296
>Q2SK05:PUR4_HAHCH Phosphoribosylformylglycinamidine synthase - Hahella chejuensis| (strain KCTC 2396) Length = 1298 Score = 382 bits (981), Expect = e-105 Identities = 229/595 (38%), Positives = 329/595 (55%), Gaps = 14/595 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 EA+TNL AK+ L+D+K S NWM AA GE +LGI I GKD Sbjct: 718 EAITNLAAAKIEKLSDIKLSANWMAAAGHPGEDEALFETVKAVGMELCPELGITIPVGKD 777 Query: 180 SLSMAAQCD-GELVK---APGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 S+SM + GE K AP +L+IS + D+ T+TP + L LL +DL GK Sbjct: 778 SMSMKTVWEEGEKQKSVTAPLSLIISGFAPVEDVRKTLTPQMDLSTPSKLLLIDLGSGKN 837 Query: 348 RLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILE 527 RLG SALAQ + +G PD+++ L F +Q+L +E + A HD SDGG+ T+ E Sbjct: 838 RLGGSALAQVYRSVGAVAPDLDNPEELAAFFACIQKLNNEGKLKAYHDRSDGGVFTTLCE 897 Query: 528 MAFAGNCGVNLNIE--LKDND-LLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVI 698 MAFA CG+ + + +KD + + LF EELG V++V + +D VK AG++ +V+ Sbjct: 898 MAFASRCGMTICFDGLVKDRTHIARELFNEELGAVVQVSEEHVDEVKTCFADAGLADHVV 957 Query: 699 --GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRT 872 GE A ++ +G+ L L+ +W ETS++++ ++ C E + Sbjct: 958 VLGEPHADQSVKFQHEGQTVLGYSRGALQKIWAETSYRMQSMRDNSECAAEEFAAIDDDN 1017 Query: 873 SPLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMS 1043 P T + ++ +KPK+ ++RE+G NS EM+AAF AGF D+ MS Sbjct: 1018 DPGLSAKLTYDVNEDIAAPFINRGAKPKIVVLREQGVNSQAEMAAAFDRAGFSAVDVHMS 1077 Query: 1044 DLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLG 1223 D+L+ SL++F+ +A GGFS+ DVL + +GWA SI FN QF+ F++R DTF+LG Sbjct: 1078 DILSGAVSLSQFKALAACGGFSFGDVLGAGEGWAKSILFNARARDQFEAFFHRKDTFALG 1137 Query: 1224 VCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMF 1400 VCNGCQ+++ L +PG D + PRF N S ++E R V + DSPSI+ Sbjct: 1138 VCNGCQMISNLKELIPGAD-----------AWPRFVRNRSEQYEARVAMVEVLDSPSILL 1186 Query: 1401 KGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPL 1580 +GM GS + I AHGEG A + + + N+A LR+ D+ T +PFNPNGSPL Sbjct: 1187 QGMAGSMMPIAVAHGEGLAEVGPEGAAALMAQKNVA-LRFVDNYGRPTMSHPFNPNGSPL 1245 Query: 1581 GIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 GI ++C+ +GR +MPHPER F W P W S W+RMF+NAR W Sbjct: 1246 GITSVCNDDGRITVMMPHPERVFRAVANSWRPSAW----SEDGAWMRMFRNARVW 1296
>Q667W1:PUR4_YERPS Phosphoribosylformylglycinamidine synthase - Yersinia| pseudotuberculosis Length = 1296 Score = 380 bits (977), Expect = e-105 Identities = 229/594 (38%), Positives = 330/594 (55%), Gaps = 14/594 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ L +K S NWM AA GE L I I GKD Sbjct: 717 EALTNIAATQIGELKRIKLSANWMSAAGHPGEDAGLYDAVRAVGEELCPALEITIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM + + + +P +LVI+A+ D+ TVTP L+ K D LL +DL G Sbjct: 777 SMSMKTRWQEGHEQREMTSPLSLVITAFARIEDVRRTVTPQLRTDKGDNALLLIDLGAGH 836 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 LG +AL Q + Q+G+ D+ +V L F +Q L++++ + A HD SDGGL+VT+ Sbjct: 837 NALGATALTQVYRQLGDKPADVRNVQQLAGFFNAMQRLVADQHLLAYHDRSDGGLLVTLA 896 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKL--HAAGVSANVI 698 EMAFAG+CGV ++I+ ND L LF EELG VI+V + V++ L H + + Sbjct: 897 EMAFAGHCGVTVDIQSLGNDALAALFNEELGAVIQVRAEQRADVEKLLADHGLANCVHYL 956 Query: 699 GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP 878 G A ++ +V E+ S LR W ETS+Q++ L+ C E + + + P Sbjct: 957 GRAVAGDTFDIRSGTDVVYSEKRSTLRLWWAETSWQMQRLRDNPDCADQEHQAKQDESDP 1016 Query: 879 LWHLSFTPKFTDKKLLSA-----SSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMS 1043 ++ T F + ++A ++PKVA++RE+G NS EM+AAFH AGF+ D+ MS Sbjct: 1017 GLNVKLT--FDPAEDIAAPFILKQARPKVAVLREQGVNSHVEMAAAFHRAGFDAVDVHMS 1074 Query: 1044 DLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLG 1223 DLL + L F+ + GGFSY DVL + +GWA SI FN + +F+ F++RP T +LG Sbjct: 1075 DLLAGRTDLQSFQTLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFEAFFHRPTTLALG 1134 Query: 1224 VCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMF 1400 VCNGCQ+M+ L +PG + PRF N S FE RF V + SPS+ Sbjct: 1135 VCNGCQMMSNLRELIPGAE-----------HWPRFVRNLSDSFEARFSLVEVASSPSLFM 1183 Query: 1401 KGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPL 1580 + M GS + I +HGEG+ D L+ + +S+L LR+ ++ VTE YP NPNGS Sbjct: 1184 QDMVGSRMPIAVSHGEGQVEVRDAAHLAALEQSHLVALRFVNNHGVVTEQYPANPNGSAN 1243 Query: 1581 GIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 GI A+ S +GR +MPHPER F W+P++W + SPW+RMF+NAR+ Sbjct: 1244 GITAVTSVSGRATVMMPHPERVFRTVSNSWHPEEWGED----SPWMRMFRNARK 1293
>Q1CKD2:PUR4_YERPN Phosphoribosylformylglycinamidine synthase - Yersinia pestis (biovar| Antiqua strain Nepal516) Length = 1296 Score = 380 bits (977), Expect = e-105 Identities = 229/594 (38%), Positives = 330/594 (55%), Gaps = 14/594 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ L +K S NWM AA GE L I I GKD Sbjct: 717 EALTNIAATQIGELKRIKLSANWMSAAGHPGEDAGLYDAVRAVGEELCPALEITIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM + + + +P +LVI+A+ D+ TVTP L+ K D LL +DL G Sbjct: 777 SMSMKTRWQEGHEQREMTSPLSLVITAFARIEDVRRTVTPQLRTDKGDNALLLIDLGAGH 836 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 LG +AL Q + Q+G+ D+ +V L F +Q L++++ + A HD SDGGL+VT+ Sbjct: 837 NALGATALTQVYRQLGDKPADVRNVQQLAGFFNAMQRLVADQHLLAYHDRSDGGLLVTLA 896 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKL--HAAGVSANVI 698 EMAFAG+CGV ++I+ ND L LF EELG VI+V + V++ L H + + Sbjct: 897 EMAFAGHCGVTVDIQSLGNDALAALFNEELGAVIQVRAEQRADVEKLLADHGLANCVHYL 956 Query: 699 GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP 878 G A ++ +V E+ S LR W ETS+Q++ L+ C E + + + P Sbjct: 957 GRAVAGDTFDIRSGTDVVYSEKRSTLRLWWAETSWQMQRLRDNPDCADQEHQAKQDESDP 1016 Query: 879 LWHLSFTPKFTDKKLLSA-----SSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMS 1043 ++ T F + ++A ++PKVA++RE+G NS EM+AAFH AGF+ D+ MS Sbjct: 1017 GLNVKLT--FDPAEDIAAPFILKQARPKVAVLREQGVNSHVEMAAAFHRAGFDAVDVHMS 1074 Query: 1044 DLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLG 1223 DLL + L F+ + GGFSY DVL + +GWA SI FN + +F+ F++RP T +LG Sbjct: 1075 DLLAGRTDLQSFQTLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFEAFFHRPTTLALG 1134 Query: 1224 VCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMF 1400 VCNGCQ+M+ L +PG + PRF N S FE RF V + SPS+ Sbjct: 1135 VCNGCQMMSNLRELIPGAE-----------HWPRFVRNLSDSFEARFSLVEVASSPSLFM 1183 Query: 1401 KGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPL 1580 + M GS + I +HGEG+ D L+ + +S+L LR+ ++ VTE YP NPNGS Sbjct: 1184 QDMVGSRMPIAVSHGEGQVEVRDAAHLAALEQSHLVALRFVNNHGVVTEQYPANPNGSAN 1243 Query: 1581 GIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 GI A+ S +GR +MPHPER F W+P++W + SPW+RMF+NAR+ Sbjct: 1244 GITAVTSVSGRATVMMPHPERVFRTVSNSWHPEEWGED----SPWMRMFRNARK 1293
>Q8ZCQ2:PUR4_YERPE Phosphoribosylformylglycinamidine synthase - Yersinia pestis| Length = 1296 Score = 380 bits (977), Expect = e-105 Identities = 229/594 (38%), Positives = 330/594 (55%), Gaps = 14/594 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ L +K S NWM AA GE L I I GKD Sbjct: 717 EALTNIAATQIGELKRIKLSANWMSAAGHPGEDAGLYDAVRAVGEELCPALEITIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM + + + +P +LVI+A+ D+ TVTP L+ K D LL +DL G Sbjct: 777 SMSMKTRWQEGHEQREMTSPLSLVITAFARIEDVRRTVTPQLRTDKGDNALLLIDLGAGH 836 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 LG +AL Q + Q+G+ D+ +V L F +Q L++++ + A HD SDGGL+VT+ Sbjct: 837 NALGATALTQVYRQLGDKPADVRNVQQLAGFFNAMQRLVADQHLLAYHDRSDGGLLVTLA 896 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKL--HAAGVSANVI 698 EMAFAG+CGV ++I+ ND L LF EELG VI+V + V++ L H + + Sbjct: 897 EMAFAGHCGVTVDIQSLGNDALAALFNEELGAVIQVRAEQRADVEKLLADHGLANCVHYL 956 Query: 699 GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP 878 G A ++ +V E+ S LR W ETS+Q++ L+ C E + + + P Sbjct: 957 GRAVAGDTFDIRSGTDVVYSEKRSTLRLWWAETSWQMQRLRDNPDCADQEHQAKQDESDP 1016 Query: 879 LWHLSFTPKFTDKKLLSA-----SSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMS 1043 ++ T F + ++A ++PKVA++RE+G NS EM+AAFH AGF+ D+ MS Sbjct: 1017 GLNVKLT--FDPAEDIAAPFILKQARPKVAVLREQGVNSHVEMAAAFHRAGFDAVDVHMS 1074 Query: 1044 DLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLG 1223 DLL + L F+ + GGFSY DVL + +GWA SI FN + +F+ F++RP T +LG Sbjct: 1075 DLLAGRTDLQSFQTLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFEAFFHRPTTLALG 1134 Query: 1224 VCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMF 1400 VCNGCQ+M+ L +PG + PRF N S FE RF V + SPS+ Sbjct: 1135 VCNGCQMMSNLRELIPGAE-----------HWPRFVRNLSDSFEARFSLVEVASSPSLFM 1183 Query: 1401 KGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPL 1580 + M GS + I +HGEG+ D L+ + +S+L LR+ ++ VTE YP NPNGS Sbjct: 1184 QDMVGSRMPIAVSHGEGQVEVRDAAHLAALEQSHLVALRFVNNHGVVTEQYPANPNGSAN 1243 Query: 1581 GIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 GI A+ S +GR +MPHPER F W+P++W + SPW+RMF+NAR+ Sbjct: 1244 GITAVTSVSGRATVMMPHPERVFRTVSNSWHPEEWGED----SPWMRMFRNARK 1293
>Q1C5E7:PUR4_YERPA Phosphoribosylformylglycinamidine synthase - Yersinia pestis (biovar| Antiqua strain Antiqua) Length = 1296 Score = 380 bits (977), Expect = e-105 Identities = 229/594 (38%), Positives = 330/594 (55%), Gaps = 14/594 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EALTN+ ++ L +K S NWM AA GE L I I GKD Sbjct: 717 EALTNIAATQIGELKRIKLSANWMSAAGHPGEDAGLYDAVRAVGEELCPALEITIPVGKD 776 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM + + + +P +LVI+A+ D+ TVTP L+ K D LL +DL G Sbjct: 777 SMSMKTRWQEGHEQREMTSPLSLVITAFARIEDVRRTVTPQLRTDKGDNALLLIDLGAGH 836 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 LG +AL Q + Q+G+ D+ +V L F +Q L++++ + A HD SDGGL+VT+ Sbjct: 837 NALGATALTQVYRQLGDKPADVRNVQQLAGFFNAMQRLVADQHLLAYHDRSDGGLLVTLA 896 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKL--HAAGVSANVI 698 EMAFAG+CGV ++I+ ND L LF EELG VI+V + V++ L H + + Sbjct: 897 EMAFAGHCGVTVDIQSLGNDALAALFNEELGAVIQVRAEQRADVEKLLADHGLANCVHYL 956 Query: 699 GEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP 878 G A ++ +V E+ S LR W ETS+Q++ L+ C E + + + P Sbjct: 957 GRAVAGDTFDIRSGTDVVYSEKRSTLRLWWAETSWQMQRLRDNPDCADQEHQAKQDESDP 1016 Query: 879 LWHLSFTPKFTDKKLLSA-----SSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMS 1043 ++ T F + ++A ++PKVA++RE+G NS EM+AAFH AGF+ D+ MS Sbjct: 1017 GLNVKLT--FDPAEDIAAPFILKQARPKVAVLREQGVNSHVEMAAAFHRAGFDAVDVHMS 1074 Query: 1044 DLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLG 1223 DLL + L F+ + GGFSY DVL + +GWA SI FN + +F+ F++RP T +LG Sbjct: 1075 DLLAGRTDLQSFQTLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFEAFFHRPTTLALG 1134 Query: 1224 VCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMF 1400 VCNGCQ+M+ L +PG + PRF N S FE RF V + SPS+ Sbjct: 1135 VCNGCQMMSNLRELIPGAE-----------HWPRFVRNLSDSFEARFSLVEVASSPSLFM 1183 Query: 1401 KGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPL 1580 + M GS + I +HGEG+ D L+ + +S+L LR+ ++ VTE YP NPNGS Sbjct: 1184 QDMVGSRMPIAVSHGEGQVEVRDAAHLAALEQSHLVALRFVNNHGVVTEQYPANPNGSAN 1243 Query: 1581 GIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNARE 1742 GI A+ S +GR +MPHPER F W+P++W + SPW+RMF+NAR+ Sbjct: 1244 GITAVTSVSGRATVMMPHPERVFRTVSNSWHPEEWGED----SPWMRMFRNARK 1293
>Q4ZX02:PUR4_PSEU2 Phosphoribosylformylglycinamidine synthase - Pseudomonas syringae pv.| syringae (strain B728a) Length = 1298 Score = 380 bits (977), Expect = e-105 Identities = 230/597 (38%), Positives = 327/597 (54%), Gaps = 16/597 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E LTN+ + + L+D+K S NWM AA GE +LGI I GKD Sbjct: 716 ETLTNIAASLIEKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKD 775 Query: 180 SLSMAAQCDGE----LVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGV--LLHVDLAKG 341 S+SM + E V +P +L+++ + DI T+TP+L++ K G+ L+ +DL +G Sbjct: 776 SMSMKTRWSDEGTEKSVTSPLSLIVTGFAPVVDIRQTLTPELRMDK-GITDLILIDLGRG 834 Query: 342 KRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTI 521 + R+G S LAQ ++G PD++D LK F V+Q L S+ I + HD SDGGL+V+ Sbjct: 835 QNRMGASILAQTHGKLGRVAPDVDDAEDLKAFFAVIQGLNSDGHILSYHDRSDGGLLVST 894 Query: 522 LEMAFAGNCGVNLNIE-LKDN--DLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS-- 686 LEMAFAG+CG+NL+++ + DN +L LF EELG VI+V D +V + AAG+ Sbjct: 895 LEMAFAGHCGLNLHLDGVADNVSELSAILFNEELGAVIQVRQDATPLVLAQFSAAGLEDC 954 Query: 687 ANVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKS 866 VIG+ E+ + GE + L+ W ETS+Q++ L+ C E + L Sbjct: 955 VAVIGQPINNDEVSISFHGEPVFSGQRRLLQRQWAETSYQIQRLRDNAECADQEFDALLE 1014 Query: 867 RTSPLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDIT 1037 +P + D + +P+VA++RE+G N EM+AAF AGF D+ Sbjct: 1015 EDNPGLTVKLGFDVNDDIAAPYIKTGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDVH 1074 Query: 1038 MSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFS 1217 MSD+L + L +F+G+ GGFSY DVL + +GWA S FN FQ F+ R D+F+ Sbjct: 1075 MSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERSDSFT 1134 Query: 1218 LGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSI 1394 LGVCNGCQ+++ L +PG + P F N S +FE R V + +S SI Sbjct: 1135 LGVCNGCQMLSNLHELIPGSEF-----------WPHFVRNRSEQFEARVAMVQVQESASI 1183 Query: 1395 MFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGS 1574 +GM GS + I AHGEG A F + + L + S LR+ D+ VTE YP NPNGS Sbjct: 1184 FLQGMAGSRMPIAIAHGEGHAEFRNDDALLEADVSGTVALRFVDNHGKVTETYPANPNGS 1243 Query: 1575 PLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 P GI + + +GR +MPHPER F Q W P+DW + W+RMF+NAR W Sbjct: 1244 PRGIGGMTTLDGRVTIMMPHPERVFRAVQNSWRPEDWNED----GAWMRMFRNARAW 1296
>Q886W6:PUR4_PSESM Phosphoribosylformylglycinamidine synthase - Pseudomonas syringae pv.| tomato Length = 1298 Score = 380 bits (977), Expect = e-105 Identities = 233/599 (38%), Positives = 333/599 (55%), Gaps = 18/599 (3%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E LTN+ +++ L+D+K S NWM AA GE +LGI I GKD Sbjct: 716 ETLTNIAASRIEKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKD 775 Query: 180 SLSMAAQCDGE----LVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGV--LLHVDLAKG 341 S+SM + E V +P +L+++ + DI T+TP+L++ K G+ L+ +DL +G Sbjct: 776 SMSMKTRWSDEGTEKSVTSPLSLIVTGFAPVVDIRKTLTPELRMDK-GITDLILIDLGRG 834 Query: 342 KRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTI 521 + R+G S LAQ ++G PD++D LK F V+Q L S+ I + HD SDGGL+V+ Sbjct: 835 QNRMGASILAQTHGKLGRVAPDVDDAEDLKAFFAVIQGLNSDGHILSYHDRSDGGLLVST 894 Query: 522 LEMAFAGNCGVNLNIE-LKDN--DLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS-- 686 LEMAFAG+CG+NL+++ L DN +L LF EELG VI+V D +V + AAG+ Sbjct: 895 LEMAFAGHCGLNLHLDGLADNVSELSAILFNEELGAVIQVRQDATPLVLAQFSAAGLEDC 954 Query: 687 ANVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKS 866 VIG+ E+ + GE + L+ W ETS+Q++ L+ C E + L Sbjct: 955 VAVIGQPINNDEVSISFLGEPVFSGQRRLLQRQWAETSYQIQRLRDNAECADQEFDALLE 1014 Query: 867 RTSPLWHLSFTPKFTDKKLLSA-----SSKPKVAIIREEGSNSDREMSAAFHAAGFEPWD 1031 +P L+ F + ++A +P+VA++RE+G N EM+AAF AGF D Sbjct: 1015 EDNP--GLTVKLGFDVNEDIAAPYIKTGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAID 1072 Query: 1032 ITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDT 1211 + MSD+L + L +F+G+ GGFSY DVL + +GWA S FN FQ F+ R D+ Sbjct: 1073 VHMSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERSDS 1132 Query: 1212 FSLGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSP 1388 F+LGVCNGCQ+++ L +PG + P F N S +FE R V + +S Sbjct: 1133 FTLGVCNGCQMLSNLHELIPGSEF-----------WPHFVRNRSEQFEARVAMVQVQESA 1181 Query: 1389 SIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPN 1568 SI +GM GS + I AHGEG A F + + L + S LR+ D+ VTE YP NPN Sbjct: 1182 SIFLQGMAGSRMPIAIAHGEGHAEFRNDDALLEADVSGTVALRFVDNHGKVTESYPANPN 1241 Query: 1569 GSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 GSP GI + + +GR +MPHPER F Q W P+DW + + W+RMF+NAR W Sbjct: 1242 GSPRGIGGMTTLDGRVTIMMPHPERVFRAVQNSWRPEDWNED----AAWMRMFRNARAW 1296
>Q48LX3:PUR4_PSE14 Phosphoribosylformylglycinamidine synthase - Pseudomonas syringae pv.| phaseolicola (strain 1448A / Race 6) Length = 1298 Score = 379 bits (974), Expect = e-104 Identities = 232/599 (38%), Positives = 332/599 (55%), Gaps = 18/599 (3%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E LTN+ + + L+D+K S NWM AA GE +LGI I GKD Sbjct: 716 ETLTNIAASCIEKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKD 775 Query: 180 SLSMAAQCDGE----LVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGV--LLHVDLAKG 341 S+SM + E V +P +L+++ + DI T+TP+L++ K G+ L+ +DL +G Sbjct: 776 SMSMKTRWSDEGTEKSVTSPLSLIVTGFAPVVDIRQTLTPELRMDK-GITDLILIDLGRG 834 Query: 342 KRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTI 521 + R+G S LAQ ++G PD++D LK F V+Q L S+ I + HD SDGGL+V+ Sbjct: 835 QNRMGASILAQTHGKLGRVAPDVDDAEDLKAFFAVIQGLNSDGHILSYHDRSDGGLLVST 894 Query: 522 LEMAFAGNCGVNLNIE-LKDN--DLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS-- 686 LEMAFAG+CG+NL+++ + DN +L LF EELG VI+V D +V + AAG+ Sbjct: 895 LEMAFAGHCGLNLHLDGVADNVSELSAILFNEELGAVIQVRQDATPLVLAQFSAAGLEDC 954 Query: 687 ANVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKS 866 VIG+ E+ + GE + L+ W ETS+Q++ L+ C E + L Sbjct: 955 VAVIGQPINNDEVSISFHGEPVFSGQRRLLQRQWAETSYQIQRLRDNAECADQEFDALLE 1014 Query: 867 RTSPLWHLSFTPKFTDKKLLSA-----SSKPKVAIIREEGSNSDREMSAAFHAAGFEPWD 1031 +P L+ F + ++A +P+VA++RE+G N EM+AAF AGF D Sbjct: 1015 EDNP--GLTVKLGFDVNEDIAAPYIKTGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAID 1072 Query: 1032 ITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDT 1211 + MSD+L + L +F+G+ GGFSY DVL + +GWA S FN FQ F+ R D+ Sbjct: 1073 VHMSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERADS 1132 Query: 1212 FSLGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSP 1388 F+LGVCNGCQ+++ L +PG + P F N S +FE R V + +S Sbjct: 1133 FTLGVCNGCQMLSNLHELIPGSEF-----------WPHFVRNRSEQFEARVAMVQVQESA 1181 Query: 1389 SIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPN 1568 SI +GM GS + I AHGEG A F + + L + S LR+ D+ VTE YP NPN Sbjct: 1182 SIFLQGMAGSRMPIAIAHGEGHAEFRNDDALLEADVSGTVALRFVDNHGKVTETYPANPN 1241 Query: 1569 GSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 GSP GI + + +GR +MPHPER F Q W P+DW + + W+RMF+NAR W Sbjct: 1242 GSPRGIGGMTTLDGRVTIMMPHPERVFRAVQNSWRPEDWNED----AAWMRMFRNARAW 1296
>Q88P16:PUR4_PSEPK Phosphoribosylformylglycinamidine synthase - Pseudomonas putida| (strain KT2440) Length = 1299 Score = 377 bits (969), Expect = e-104 Identities = 233/597 (39%), Positives = 322/597 (53%), Gaps = 16/597 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E LTNL +++ L+D+K S NWM AA GE +LGI I GKD Sbjct: 716 ETLTNLAASRIEKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKD 775 Query: 180 SLSMAAQCDGELVK----APGNLVISAYVTCPDITLTVTPDLKLGKDGV-LLHVDLAKGK 344 S+SM + E V+ +P +L+I+ + DI T+TP L++ K L+ +DL +GK Sbjct: 776 SMSMKTKWSDEGVEKSVTSPMSLIITGFAPVTDIRKTLTPQLRMDKGETDLILIDLGRGK 835 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 R+G S LAQ + +I PD++D LK F V+Q L ++ + A HD SDGGL+ T+L Sbjct: 836 NRMGASILAQTYGKIAAQAPDVDDAEDLKAFFAVIQGLNADGHLLAYHDRSDGGLVTTVL 895 Query: 525 EMAFAGNCGVNLNIE-LKDN--DLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSAN- 692 EMAFAG+CG++L ++ L D+ ++ LF EELG VI+V D V + AAG+ Sbjct: 896 EMAFAGHCGLDLQLDPLTDSKGEVPAILFNEELGAVIQVRQDATPDVLAQFSAAGLGEEC 955 Query: 693 --VIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKS 866 VIG+ E+ + ++GEV + L+ W ETS+Q++ L+ C E + L Sbjct: 956 VAVIGKPVNNAEVTISLNGEVLFDDDRRMLQRQWAETSYQIQRLRDNADCADQEFDLLLE 1015 Query: 867 RTSPLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDIT 1037 +P + D + +P+VAI+RE+G N EM+AAF AGF D+ Sbjct: 1016 EDNPGLSVKLGFDVNDDIAAPYIKKGVRPQVAILREQGVNGQVEMAAAFDRAGFAAIDVH 1075 Query: 1038 MSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFS 1217 MSD+L + F+G+ GGFSY DVL + +GWA S FN FQ F+ R D+F+ Sbjct: 1076 MSDILAGRVDFEAFKGLVACGGFSYGDVLGAGEGWAKSALFNARARDAFQAFFERTDSFA 1135 Query: 1218 LGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSI 1394 LGVCNGCQ+M+ L +PG + P F N S +FE R V + S SI Sbjct: 1136 LGVCNGCQMMSNLHELIPGTEY-----------WPHFVRNRSEQFEARVAMVEVQKSNSI 1184 Query: 1395 MFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGS 1574 +GM GS + I AHGEG A F L + S LRY D+ VTE YP NPNGS Sbjct: 1185 FLQGMAGSRMPIAIAHGEGHAEFASEEALLEADVSGCVALRYVDNHGKVTEAYPANPNGS 1244 Query: 1575 PLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 P GI L S +GR +MPHPER F Q W P +WQ + + +RMF+NAR W Sbjct: 1245 PRGITGLTSRDGRVTIMMPHPERVFRAVQNSWRPDEWQED----AALMRMFRNARVW 1297
>Q085S1:PUR4_SHEFN Phosphoribosylformylglycinamidine synthase - Shewanella frigidimarina| (strain NCIMB 400) Length = 1293 Score = 377 bits (968), Expect = e-103 Identities = 222/589 (37%), Positives = 322/589 (54%), Gaps = 10/589 (1%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E++ N+ + S +K S NWM A GE +LGI I GKD Sbjct: 716 ESIMNIAGTDIGSFKRIKLSANWMSPAGHPGEDAGLYQAVKAIGEDLCPELGITIPVGKD 775 Query: 180 SLSMAAQCDG----ELVKAPGNLVISAYVTCPDITLTVTPDLKLGK-DGVLLHVDLAKGK 344 S+SM + + V +P +LVI+A+ DI TVTP L+ K D LL +DL+ G+ Sbjct: 776 SMSMKTAWEDNGTQKTVTSPMSLVITAFGVVQDIRKTVTPQLRSDKGDSALLMLDLSNGQ 835 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG S LAQ + ++G+ P ++ L FEV+Q+L++++ + A HD SDGGL T++ Sbjct: 836 NRLGGSCLAQVYSELGDIAPTLDKTANLAGFFEVMQQLVADQAVMAYHDRSDGGLFTTLV 895 Query: 525 EMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGE 704 EMAFAGN G+ +++ L+ LF EE+G VI+V D + + A GV+ + IG Sbjct: 896 EMAFAGNTGLTIDLASLSGTDLERLFNEEIGAVIQVSAIDAKAIAAQFEAKGVTCHHIGG 955 Query: 705 VTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSP-- 878 + A +I + V + + LR LW ET+++++ L+ C + E E + +P Sbjct: 956 LQTADKISINDGERVIFADSRTALRTLWSETTYRMQALRDNPECAREEYELKQQADAPGL 1015 Query: 879 LWHLSFTP-KFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLN 1055 L F P + + PK+AI+RE+G NS EM+AAF AGFE D+ MSD+L+ Sbjct: 1016 TVKLGFNPSEDVAAPYILKGVAPKMAILREQGVNSHVEMAAAFDRAGFESRDVHMSDILS 1075 Query: 1056 QKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNG 1235 + SL EF+G+ GGFSY DVL + +GWA SI FN +F F+ R + +LGVCNG Sbjct: 1076 GRISLEEFQGLVACGGFSYGDVLGAGEGWAKSILFNDRARDEFSRFFERDSSIALGVCNG 1135 Query: 1236 CQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME 1412 CQ+++ L +PG + PRF N S RFE RF V + +PS+ F+GM Sbjct: 1136 CQMLSNLKEIIPGSE-----------HWPRFVRNRSERFEARFSLVEVQQNPSVFFEGMV 1184 Query: 1413 GSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAA 1592 GS + I +HGEG F + L++ S LRY D + YP NPNGS G+ Sbjct: 1185 GSRMPIAVSHGEGLVEFANAQALANAEASGTIALRYVDGHGQIATQYPENPNGSANGLTG 1244 Query: 1593 LCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 +C+ +GR +MPHPER F W+P +W + SPW+RMF+NAR Sbjct: 1245 ICTTDGRVTIMMPHPERVFRTVANSWHPDNWGED----SPWMRMFRNAR 1289
>Q4KHS6:PUR4_PSEF5 Phosphoribosylformylglycinamidine synthase - Pseudomonas fluorescens| (strain Pf-5 / ATCC BAA-477) Length = 1298 Score = 377 bits (967), Expect = e-103 Identities = 229/598 (38%), Positives = 330/598 (55%), Gaps = 17/598 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E LTN+ +++ ++D+K S NWM AA GE +LGI I GKD Sbjct: 716 ETLTNIAASRINKISDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKD 775 Query: 180 SLSMAAQCDGE----LVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGV-LLHVDLAKGK 344 S+SMA + + E V +P +L+++ + DI T+TP L++ K L+ +DL +G+ Sbjct: 776 SMSMATRWNEEGVDKSVTSPLSLIVTGFAPVADIRQTLTPQLRMDKGTTDLILIDLGRGQ 835 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 R+G S LAQ ++G+ PD++D LK F V+Q L ++ + A HD SDGGL+V+ + Sbjct: 836 NRMGASILAQTHGKLGSQAPDVDDAEDLKAFFAVIQGLNADGHLLAYHDRSDGGLLVSAV 895 Query: 525 EMAFAGNCGVNLNIE-LKDN--DLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVS--A 689 EMAFAG+CG+NL+++ + +N ++ LF EELG VI+V D V + AAG+ Sbjct: 896 EMAFAGHCGLNLSLDAVAENTAEIAAILFNEELGAVIQVRQDATPDVLAQFSAAGLGDCV 955 Query: 690 NVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSR 869 VIG+ E+ + +GE + L+ W ETS+Q++ L+ C + E + + Sbjct: 956 AVIGQPINNGEVSISYNGESVFTGQRRLLQRQWAETSYQIQRLRDNADCAEQEFDVVLEE 1015 Query: 870 TSPLWHLSFTPKFTDKKLLSA-----SSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDI 1034 +P LS F + ++A +P+VA++RE+G N EM+AAF AGF D+ Sbjct: 1016 DNP--GLSVKLGFDVNQDIAAPYIKKGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDV 1073 Query: 1035 TMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTF 1214 MSD+L + L +F+G+ GGFSY DVL + +GWA S FN FQ F+ R D+F Sbjct: 1074 HMSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERTDSF 1133 Query: 1215 SLGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPS 1391 +LGVCNGCQ+M+ L +PG + P F N S +FE R V + +S S Sbjct: 1134 TLGVCNGCQMMSNLHELIPGSEF-----------WPHFVRNRSEQFEARVAMVQVQESNS 1182 Query: 1392 IMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNG 1571 I +GM GS + I AHGEG A F L + S LR+ D+ VTE YP NPNG Sbjct: 1183 IFLQGMAGSRMPIAIAHGEGHAEFESEEALLEADLSGCVALRFVDNHGKVTERYPANPNG 1242 Query: 1572 SPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 SP GI L S +GR +MPHPER F Q W P +W + W+RMF+NAR W Sbjct: 1243 SPRGITGLTSRDGRVTIMMPHPERVFRAVQNSWRPDEWNED----GAWMRMFRNARVW 1296
>O14228:PUR4_SCHPO Probable phosphoribosylformylglycinamidine synthase -| Schizosaccharomyces pombe (Fission yeast) Length = 1323 Score = 375 bits (962), Expect = e-103 Identities = 234/600 (39%), Positives = 333/600 (55%), Gaps = 19/600 (3%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXI-QLGIAIDGGKD 179 E + NLV A + +L ++ S NWM A GEG LGI+I GKD Sbjct: 733 ECIMNLVAASIPALDRIRLSANWMAAPSHPGEGAKLYEAVQAIGLELCPSLGISIPVGKD 792 Query: 180 SLSMAAQC--DG--ELVKAPGNLVISAYVTCPDITLTVTPDLKLGKD---GVLLHVDLAK 338 S+SM+ + DG + V AP +L+I+ + D+ TP L+ +D L+ +DLA Sbjct: 793 SMSMSMKWNEDGREKSVTAPLSLIITGFSPVDDLYSIWTPQLRKVEDIGSTSLIFIDLAN 852 Query: 339 GKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVT 518 GK+RLG S LAQ++ Q+G++ PD++++ K V+ +L I A HD SDGGL VT Sbjct: 853 GKQRLGGSILAQSYKQLGDEVPDLDNLDTFKNFINVITQLHKTNYIQAYHDKSDGGLFVT 912 Query: 519 ILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANV- 695 + EMAFAG+ G+ ++ +D + LF EELG VI+V D+ V + A G+S V Sbjct: 913 LSEMAFAGHVGIECELDSLSSDNIAALFNEELGAVIQVCDRDIAKVLELFAANGLSTCVH 972 Query: 696 -IGEVTA--APEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKS 866 IG+V + A I G++ K S L +W ETS++++E++ C + E E + Sbjct: 973 RIGKVLSGQAQTISFSRSGKIIFKSTRSKLHGIWHETSYKMQEIRDNPECARQEMENIAD 1032 Query: 867 RTSP--LWHLSFTPKFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITM 1040 P +HL+F P + L+ +S+PKVAI+RE+G N EM+ AF+A+GF D+ M Sbjct: 1033 NNDPGLGYHLTFDPNVSVTADLALTSRPKVAILREQGVNGYLEMAYAFYASGFTAVDVHM 1092 Query: 1041 SDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYN-RPDTFS 1217 +D+L+ + L +F GIA GGFSY DVL S GWA SI ++ +F F+N R DTF Sbjct: 1093 TDILSGRVHLDDFVGIAACGGFSYGDVLGSGNGWATSILLHEDARNEFYRFFNERKDTFG 1152 Query: 1218 LGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGD---S 1385 LG+CNGCQL + L +PG S P FT NES ++E R + + I + S Sbjct: 1153 LGICNGCQLFSRLKSLIPGA-----------KSWPMFTFNESAQYEGRAVMLKIDETSGS 1201 Query: 1386 PSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNP 1565 SI + M GS+L + AHGEGRA F + K L + Y ++ N T YPFNP Sbjct: 1202 KSIFTESMAGSSLPVVVAHGEGRAVFDSESDYEQFKKEGLDLIYYVNNYNERTSRYPFNP 1261 Query: 1566 NGSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 NGS IA + SP GR LA+MPHPER + +YP E PW+R+FQ+AR+W Sbjct: 1262 NGSRDAIAGVRSPCGRFLAMMPHPERVVLKVANSYYPHSKASEWGVHGPWIRLFQSARKW 1321
>Q9JWC5:PUR4_NEIMA Phosphoribosylformylglycinamidine synthase - Neisseria meningitidis| serogroup A Length = 1320 Score = 368 bits (944), Expect = e-101 Identities = 230/618 (37%), Positives = 335/618 (54%), Gaps = 38/618 (6%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQLGIAIDGGKDS 182 EA+TN+ A + + ++K S NWM A +GE L ++I GKDS Sbjct: 718 EAITNIAAANIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDS 777 Query: 183 LSMAAQC-DGELVKA---PGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKRR 350 LSM DGE K+ P +L+ISA+ D+ TVTP+LK +D VLL VDL GK R Sbjct: 778 LSMKTVWQDGEEKKSVVSPLSLIISAFAPVQDVRKTVTPELKNVEDSVLLFVDLGFGKAR 837 Query: 351 LGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEM 530 +G SA Q ++ + D PD++D LK + V+Q+L++E + A HD SDGGL ++EM Sbjct: 838 MGGSAFGQVYNNMSGDAPDLDDTSRLKAFYNVIQQLVAEDKLLAYHDRSDGGLFAVLVEM 897 Query: 531 AFAGNCGVNLNIELK---------------------------DNDLLQTLFAEELGLVIE 629 AFAG CG+++++ L + +TLF EELG VI+ Sbjct: 898 AFAGRCGLDIDLNLLLAQTFITNHTALSQSLRTEEVKALAEWQETIARTLFNEELGAVIQ 957 Query: 630 VHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLV-DGEVRL-KERTSDLRDLWEETSF 803 V D+ + + + NV T E L++ DG+ L + L+ W+ETS Sbjct: 958 VRKQDVADIINLFYQQQLHHNVFEIGTLTDENTLIIRDGQTHLISDNLIKLQQTWQETSH 1017 Query: 804 QLEELQRLKSCVKLEKE--GLKSRTSPLWHLSF-TPKFTDKKLLSASSKPKVAIIREEGS 974 Q++ L+ +C E G R++ +L F + +++ +KPK+AI+RE+G Sbjct: 1018 QIQRLRDNPACADSEFALIGDNGRSALFANLKFDVNEDIAAPFINSGAKPKIAILREQGV 1077 Query: 975 NSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASI 1154 N EM+AAF AGF+ +D+ MSDL+ + L +F+ +A GGFSY DVL + KGWA SI Sbjct: 1078 NGQIEMAAAFTRAGFDAYDVHMSDLMAGRVHLADFKMLAACGGFSYGDVLGAGKGWAKSI 1137 Query: 1155 RFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDMSQPRFTHN 1334 F+ L QF F+ P+T +LGVCNGCQ+++ L + I G+ G P+F N Sbjct: 1138 LFHPALRDQFAAFFTDPNTLTLGVCNGCQMVSNLAEI----IPGTAG------WPKFKRN 1187 Query: 1335 ESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFP--DGNVLSDVVKSNLA 1508 S +FE R V + S S++ M+GS+L + +HGEGRA F GN+ +D+ Sbjct: 1188 LSEQFEARLSMVHVPKSASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLG----I 1243 Query: 1509 PLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQ 1688 L+Y D N +T+ YP NPNGSP GIA + + +GR +MPHPER + Q W P+DW Sbjct: 1244 ALQYVDGQNQITQTYPLNPNGSPQGIAGVTNADGRVTIMMPHPERVYRAAQMSWKPEDW- 1302 Query: 1689 VEKSGPSPWLRMFQNARE 1742 E SG W R+F AR+ Sbjct: 1303 TELSG---WYRLFAGARK 1317
>P43847:PUR4_HAEIN Phosphoribosylformylglycinamidine synthase - Haemophilus influenzae| Length = 1297 Score = 362 bits (929), Expect = 3e-99 Identities = 224/592 (37%), Positives = 320/592 (54%), Gaps = 13/592 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EA+TN+ + + +K S NWM AA GE LG+ I GKD Sbjct: 719 EAITNIAGTLIGEMKRIKLSANWMSAAGHTGEDAGLYEAVKAVGEELCPALGLTIPVGKD 778 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKD-GVLLHVDLAKGK 344 S+SM + + V AP +LVISA+ D+ T+TP L+ K LL +DL +G Sbjct: 779 SMSMKTTWIDNGEQKSVTAPLSLVISAFARVEDVRKTLTPQLRTDKGFSSLLLIDLGEGH 838 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG +ALAQ + Q+G+ D+ V LK + +Q L++E + A HD SDGGLI T+ Sbjct: 839 NRLGATALAQVYKQLGDKPADVVKVQRLKDFYNAMQTLVAEDKLLAYHDRSDGGLITTLA 898 Query: 525 EMAFAGNCGVNLNIE-LKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANV-- 695 EMAFAG+CGV ++I L DNDL LF EELG VI+V L+ V++ L A + + Sbjct: 899 EMAFAGHCGVEVDISALGDNDLA-VLFNEELGAVIQVADSQLESVREVLKAHNLLGIIHQ 957 Query: 696 IGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTS 875 +G VTA E+ E+ S+LR +W E ++Q++ L+ C + E E K+ Sbjct: 958 LGTVTADDRFEISRGSHKLFSEKRSELRSIWAELTYQMQRLRDNPECAEQEFEAKKNPDD 1017 Query: 876 PLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSD 1046 T + ++ KP +AI+RE+G NS EM+AAF AGF D+ MSD Sbjct: 1018 KGLSAFLTYDVNEDITAPFINKGVKPTIAILREQGVNSHYEMAAAFDRAGFNAIDVHMSD 1077 Query: 1047 LLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGV 1226 L+ + +L EF + GGFSY DVL + GWA SI FN L +QF +F+ P+T +LGV Sbjct: 1078 LMIGRRNLAEFNAMVACGGFSYGDVLGAGGGWAKSILFNPKLHEQFSQFFINPNTLTLGV 1137 Query: 1227 CNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFK 1403 CNGCQ+++ L +PG + + P F N+S RFE R V I + S+ F Sbjct: 1138 CNGCQMISNLAEIIPGTE-----------NWPHFVRNKSERFEARVSLVKINEVDSVWFA 1186 Query: 1404 GMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLG 1583 GM GS + I +HGEG+ F + + + +Y D+ + TE+YP NPNGS G Sbjct: 1187 GMAGSHMPIAVSHGEGQVKFKSVEQFAGLKAQGIIAAQYIDNNGSPTELYPANPNGSSEG 1246 Query: 1584 IAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 I A+ + +GR +MPHPER F W+P++W + W+R+F+NAR Sbjct: 1247 ITAITNLDGRVAIMMPHPERVFRAVSNSWHPENWTED----GAWMRLFRNAR 1294
>Q4QME6:PUR4_HAEI8 Phosphoribosylformylglycinamidine synthase - Haemophilus influenzae| (strain 86-028NP) Length = 1297 Score = 362 bits (929), Expect = 3e-99 Identities = 224/592 (37%), Positives = 320/592 (54%), Gaps = 13/592 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EA+TN+ + + +K S NWM AA GE LG+ I GKD Sbjct: 719 EAITNIAGTHIGEMKRIKLSANWMSAAGHTGEDAGLYEAVKAVGEELCPALGLTIPVGKD 778 Query: 180 SLSMAAQC----DGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKD-GVLLHVDLAKGK 344 S+SM + + V AP +LVISA+ D+ T+TP L+ K LL +DL +G Sbjct: 779 SMSMKTTWIDNGEQKSVTAPLSLVISAFARVEDVRKTLTPQLRTDKGLSSLLLIDLGEGH 838 Query: 345 RRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTIL 524 RLG +ALAQ + Q+G+ D+ V LK + +Q L++E + A HD SDGGLI T+ Sbjct: 839 NRLGATALAQVYKQLGDKPADVVKVQRLKDFYNAMQTLVAEDKLLAYHDRSDGGLITTLA 898 Query: 525 EMAFAGNCGVNLNIE-LKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSA--NV 695 EMAFAG+CGV ++I L DNDL LF EELG VI+V L+ V++ L A + + Sbjct: 899 EMAFAGHCGVEVDISALGDNDLA-VLFNEELGAVIQVADSQLESVREVLKAHNLLGITHQ 957 Query: 696 IGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTS 875 +G VTA E+ E+ S+LR +W E ++Q++ L+ C + E E K+ Sbjct: 958 LGTVTADDRFEISRGSHKLFSEKRSELRSIWAELTYQMQRLRDNPECAEQEFEAKKNPDD 1017 Query: 876 PLWHLSFTPKFTDK---KLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSD 1046 T + ++ KP +AI+RE+G NS EM+AAF AGF D+ MSD Sbjct: 1018 KGLSAFLTYDVNEDITAPFINKGVKPTIAILREQGVNSHYEMAAAFDRAGFNAIDVHMSD 1077 Query: 1047 LLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGV 1226 L+ + +L EF + GGFSY DVL + GWA SI FN L +QF +F+ P+T +LGV Sbjct: 1078 LMIGRRNLAEFNAMVACGGFSYGDVLGAGGGWAKSILFNPKLHEQFSQFFINPNTLTLGV 1137 Query: 1227 CNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFK 1403 CNGCQ+++ L +PG + + P F N+S RFE R V I + S+ F Sbjct: 1138 CNGCQMISNLAEIIPGTE-----------NWPHFVRNKSERFEARVSLVKINEVDSVWFA 1186 Query: 1404 GMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLG 1583 GM GS + I +HGEG+ F + + + +Y D+ + TE+YP NPNGS G Sbjct: 1187 GMAGSHMPIAVSHGEGQVKFKSVEQFAGLKAQGIIAAQYIDNNGSPTELYPANPNGSAEG 1246 Query: 1584 IAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAR 1739 I A+ + +GR +MPHPER F W+P++W + W+R+F+NAR Sbjct: 1247 ITAITNLDGRVAIMMPHPERVFRAVSNSWHPENWTED----GAWMRLFRNAR 1294
>Q9JXK5:PUR4_NEIMB Phosphoribosylformylglycinamidine synthase - Neisseria meningitidis| serogroup B Length = 1320 Score = 362 bits (928), Expect = 4e-99 Identities = 228/618 (36%), Positives = 332/618 (53%), Gaps = 38/618 (6%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQLGIAIDGGKDS 182 EA+TN+ + + ++K S NWM A +GE L ++I GKDS Sbjct: 718 EAITNIAAVNIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDS 777 Query: 183 LSMAAQC-DGELVKA---PGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKRR 350 LSM DGE K+ P +L+ISA+ D+ TVTP+LK +D VLL VDL GK R Sbjct: 778 LSMKTVWQDGEEKKSVVSPLSLIISAFAPVKDVRKTVTPELKNVEDSVLLFVDLGFGKAR 837 Query: 351 LGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEM 530 +G SA Q ++ + D PD++D LK + V+Q+L++E + A HD SDGGL ++EM Sbjct: 838 MGGSAFGQVYNNMSGDAPDLDDTGRLKAFYSVIQQLVAENKLLAYHDRSDGGLFAVLVEM 897 Query: 531 AFAGNCGVNLNIELK---------------------------DNDLLQTLFAEELGLVIE 629 AFAG CG+++++ L + +TLF EELG VI+ Sbjct: 898 AFAGRCGLDIDLNLLLAQTFITNHTALSQSLRTEEVKALAEWQETIARTLFNEELGAVIQ 957 Query: 630 VHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLV-DGEVRL-KERTSDLRDLWEETSF 803 V D+ + + + NV T E L++ DG+ L + L+ W+ETS Sbjct: 958 VRKQDVADIINLFYQQQLHHNVFEIGTLTDENTLIIRDGQTHLISDNLIKLQQTWQETSH 1017 Query: 804 QLEELQRLKSCVKLEKE--GLKSRTSPLWHLSF-TPKFTDKKLLSASSKPKVAIIREEGS 974 Q++ L+ +C E G R++ + F + +++ +KPK+AI+RE+G Sbjct: 1018 QIQRLRDNPACADSEFALIGDNERSALFADVKFDVNEDIAAPFINSGAKPKIAILREQGV 1077 Query: 975 NSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASI 1154 N EM+AAF AGF+ +D+ MSDL+ + L +F+ +A GGFSY DVL + +GWA SI Sbjct: 1078 NGQIEMAAAFTRAGFDAYDVHMSDLMAGRIHLADFKMLAACGGFSYGDVLGAGEGWAKSI 1137 Query: 1155 RFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDMSQPRFTHN 1334 F+ L QF F+ PDT +LGVCNGCQ+++ L + I G+ G P+F N Sbjct: 1138 LFHPALRDQFAAFFADPDTLTLGVCNGCQMVSNLAEI----IPGTAG------WPKFKRN 1187 Query: 1335 ESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFP--DGNVLSDVVKSNLA 1508 S +FE R V + S S++ M+GS+L + +HGEGRA F GN+ +D+ Sbjct: 1188 LSEQFEARLSMVHVPKSASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLG----I 1243 Query: 1509 PLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQ 1688 L+Y D N VT+ YP NPNGSP GIA + + +GR +MPHPER + Q W P+ W Sbjct: 1244 ALQYIDGQNQVTQTYPLNPNGSPQGIAGVTNADGRITIMMPHPERVYRAAQMSWKPEGW- 1302 Query: 1689 VEKSGPSPWLRMFQNARE 1742 E SG W R+F AR+ Sbjct: 1303 TELSG---WYRLFAGARK 1317
>P38972:PUR4_YEAST Phosphoribosylformylglycinamidine synthase - Saccharomyces cerevisiae| (Baker's yeast) Length = 1358 Score = 349 bits (895), Expect = 3e-95 Identities = 230/606 (37%), Positives = 325/606 (53%), Gaps = 25/606 (4%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 E+L N+ A V SL +K S NWM A GEG LG+AI GKD Sbjct: 762 ESLLNIFAADVKSLNHIKLSANWMSPASHQGEGSKLYEAVQALGLDLCPALGVAIPVGKD 821 Query: 180 SLSMAAQCDGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKD-GVLLHVDLAKGK--RR 350 S+SM + D + V AP +L I+A+ + + T TP L D VL+ VDL+ + + Sbjct: 822 SMSMKMKWDDKEVTAPLSLNITAFAPVFNTSKTWTPLLNRNTDDSVLVLVDLSAKQETKS 881 Query: 351 LGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSER--LISAGHDISDGGLIVTIL 524 LG SAL Q ++Q+GN P + D LK E + +L ++ ++ A HD SDGGL++T+L Sbjct: 882 LGASALLQVYNQVGNKSPTVYDNAILKGFLESLIQLHQQKEDIVLAYHDRSDGGLLITLL 941 Query: 525 EMAFAGNCGVNLNIELKD-NDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIG 701 EMAFA CG+ +NI+ D L LF EELG V ++ +L ++ L+ GV+ I Sbjct: 942 EMAFASRCGLEINIDGGDLESQLTNLFNEELGAVFQISAKNLSKFEKILNENGVAKEYIS 1001 Query: 702 EVTA----APEIELL--VDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLK 863 V + EI+++ +V S+L W +TS+++++L+ + E + Sbjct: 1002 IVGKPSFQSQEIKIINSTTNDVIYANSRSELEQTWSKTSYEMQKLRDNPKTAEEEFASIT 1061 Query: 864 SRTSP--LWHLSFTPKFTDKKLLSASS-KPKVAIIREEGSNSDREMSAAFHAAGFEPWDI 1034 P + L++ P K L SS +PKVAI+RE+G N EM+ F AGF D+ Sbjct: 1062 DDRDPGLQYALTYNPADDMKIGLELSSQRPKVAILREQGVNGQMEMAWCFQQAGFNSVDV 1121 Query: 1035 TMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYN-RPDT 1211 TM+DLL + L +F G+A GGFSY DVL + GWA S+ +++ + QF +F+N R DT Sbjct: 1122 TMTDLLEGRFHLDDFIGLAACGGFSYGDVLGAGAGWAKSVLYHEGVRSQFSKFFNERQDT 1181 Query: 1212 FSLGVCNGCQLMALL-GWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSP 1388 F+ G CNGCQ ++ L +PG + + P F N S ++E R V I Sbjct: 1182 FAFGACNGCQFLSRLKDIIPGCE-----------NWPSFERNVSEQYEARVCMVQISQEK 1230 Query: 1389 ------SIMFKGMEGSTLGIWSAHGEGRAFFP-DGNVLSDVVKSNLAPLRYCDDANNVTE 1547 S+ GM GS L I AHGEG+A F L K L +RY D+ NVTE Sbjct: 1231 DNSSEESVFLNGMAGSKLPIAVAHGEGKATFSKSAEQLEKFEKDGLCCIRYVDNYGNVTE 1290 Query: 1548 VYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMF 1727 +PFNPNGS GIA + SPNGR LA+MPHPER + WYP+ E G PW+R+F Sbjct: 1291 RFPFNPNGSTNGIAGIKSPNGRVLAMMPHPERVCRLEANSWYPEGKYEEWGGYGPWIRLF 1350 Query: 1728 QNAREW 1745 ++AR W Sbjct: 1351 RSARRW 1356
>Q5F7J4:PUR4_NEIG1 Phosphoribosylformylglycinamidine synthase - Neisseria gonorrhoeae| (strain ATCC 700825 / FA 1090) Length = 1314 Score = 347 bits (889), Expect = 1e-94 Identities = 223/617 (36%), Positives = 327/617 (52%), Gaps = 37/617 (5%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQLGIAIDGGKDS 182 EA+TN+ + + ++K S NWM A +GE L ++I GKDS Sbjct: 714 EAITNIAAVNIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDS 773 Query: 183 LSMAAQC-DGELVKA---PGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKRR 350 LSM DGE K+ P +L+ISA+ D+ TVTP+LK + VLL +DL GK R Sbjct: 774 LSMKTVWQDGEEKKSVVSPLSLIISAFAPVKDVRKTVTPELKNVEGSVLLFIDLGFGKAR 833 Query: 351 LGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEM 530 +G SA Q ++ + D PD++D LK + V+Q+L++E + A HD SDGGL T+ EM Sbjct: 834 MGGSAFGQVYNNMSGDAPDLDDAGRLKAFYSVIQQLVAEDKLLAYHDRSDGGLFATLAEM 893 Query: 531 AFAGNCGVNLNI-------------------------ELKDNDLLQTLFAEELGLVIEVH 635 AFA CG++ +I EL ++ ++ LF EELG VI++ Sbjct: 894 AFAARCGISADIDCLMDKFLPIHLPDFQGDPAEDLSDELYNHAAIKILFNEELGAVIQIR 953 Query: 636 LDDLDVVKQKLHAAGVSANV--IGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQL 809 D D V AG++ V IG E L++ +DL+ W+ETS + Sbjct: 954 QKDRDYVDAAFETAGLTDAVSRIGSPDFDNEFISFFGYGYFLEQNRADLQRAWQETSHAI 1013 Query: 810 EELQRLKSCVKLEKE--GLKSRTSPLWHLSF-TPKFTDKKLLSASSKPKVAIIREEGSNS 980 + L+ +C E G R++ + F + +++ +KPK+AI+RE+G N Sbjct: 1014 QRLRDNPACADSEFALIGDNERSALFADVKFDVNEDIAAPFINSGAKPKIAILREQGVNG 1073 Query: 981 DREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRF 1160 EM+AAF AGF+ +D+ MSDL+ + L +F+ +A GGFSY DVL + +GWA SI F Sbjct: 1074 QIEMAAAFTRAGFDAYDVHMSDLMAGRFRLADFKMLAACGGFSYGDVLGAGEGWAKSILF 1133 Query: 1161 NQPLIQQFQEFYNRPDTFSLGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNE 1337 + L QF F+ P+T +LGVCNGCQ+++ L +PG + + P+F N Sbjct: 1134 HPALRDQFAAFFADPNTLTLGVCNGCQMVSNLAEIIPGAE-----------TWPKFKRNL 1182 Query: 1338 SGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFP--DGNVLSDVVKSNLAP 1511 S +FE R V + S S++ M+ S+L + +HGEGRA F GN+ +D+ Sbjct: 1183 SEQFEARLNMVHVPKSASLILNEMQDSSLPVVVSHGEGRADFALHGGNISADLG----IA 1238 Query: 1512 LRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQV 1691 L+Y D N VT+ YP NPNGSP GIA + + +GR +MPHPER + Q P+ W Sbjct: 1239 LQYVDGQNQVTQTYPLNPNGSPQGIAGITNADGRVTIMMPHPERVYRAAQMSRKPEGW-T 1297 Query: 1692 EKSGPSPWLRMFQNARE 1742 E SG W R+F AR+ Sbjct: 1298 ELSG---WYRLFAGARK 1311
>Q8PGR7:PUR4_XANAC Phosphoribosylformylglycinamidine synthase - Xanthomonas axonopodis| pv. citri Length = 1348 Score = 343 bits (880), Expect = 2e-93 Identities = 229/634 (36%), Positives = 316/634 (49%), Gaps = 52/634 (8%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EA+TNL A V +L +K S NWM AA GE L +++ GKD Sbjct: 741 EAITNLCAAPVQTLDSIKLSANWMAAAGHSGEDALLYDAVRAIGMELCPALELSVPVGKD 800 Query: 180 SLSMAAQCD-----------------------------GELVKA--PGNLVISAYVTCPD 266 SLSM AQ GE +K+ P +L+ISA+ D Sbjct: 801 SLSMQAQWQVGNRESGIGNGETPQPSASTIPDSPFPIPGETLKSVSPVSLIISAFAPVGD 860 Query: 267 ITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQ------AFDQIGNDCPDIEDVPYL 428 + +TP L+ G++ L + L GK+RLG S LAQ A G + PD++D L Sbjct: 861 VRTQLTPLLRSGEESELWLIGLGGGKQRLGGSVLAQVYADDTALPAFGGEVPDLDDAQRL 920 Query: 429 KKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE 608 + FE++++ L+ A HD SDGG + EMAFA G+++ ++ +D ++LF E Sbjct: 921 RSFFELIRDARDSGLLLAYHDRSDGGAFAALCEMAFASRQGLDITLDAWGDDAFRSLFNE 980 Query: 609 ELGLVIEVHLDD----LDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDL 776 ELG V+++ +D D+V++ HA A I T P I + G V + R +L Sbjct: 981 ELGAVVQIASEDRAAFADLVER--HALTECAQRIARPTGTPRIRVSGQGRVLAEWRWEEL 1038 Query: 777 RDLWEETSFQLEELQRLKSCVKLEK--------EGLKSRTSPLWHLSFTPKF-TDKKLLS 929 D W + +++L+ E+ GL+ + L F P ++ Sbjct: 1039 FDAWWSVTHAMQKLRDNPDSADEERALARDFKASGLRPK------LVFDPSDDVAAPFVA 1092 Query: 930 ASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFS 1109 ++PKVAI+RE+G N EM+ F AGF P+D+ MSDL+ + L+ F G A GGFS Sbjct: 1093 TGTRPKVAILREQGVNGQIEMAYNFERAGFRPYDVHMSDLIEGRVDLSAFVGFAACGGFS 1152 Query: 1110 YADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMA-LLGWVPGPDIGG 1286 Y DVL + +GWA SI L F F+ R DTF+LGVCNGCQ+++ L +PG + Sbjct: 1153 YGDVLGAGRGWATSILERSALRDAFAAFFARSDTFALGVCNGCQMLSQLKDIIPGAE--- 1209 Query: 1287 SLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFP 1466 PRF N S +FE R + + +SPSI +GM GS + + AHGEGRA F Sbjct: 1210 --------HWPRFLRNRSEQFEARTALLEVVESPSIFLRGMAGSRIPVAVAHGEGRAEFD 1261 Query: 1467 DGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 D + +A LRY D V YP NPNGSP GI L S +GR LMPHPER+ Sbjct: 1262 SA---VDQAAARVA-LRYIDGDGAVASQYPLNPNGSPDGITGLTSSDGRVTILMPHPERT 1317 Query: 1647 FMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREWC 1748 WYP DW SPWLRMF+NAR WC Sbjct: 1318 PRSANLSWYPVDW----GDDSPWLRMFRNARVWC 1347
>Q8PCQ7:PUR4_XANCP Phosphoribosylformylglycinamidine synthase - Xanthomonas campestris| pv. campestris Length = 1348 Score = 332 bits (850), Expect = 5e-90 Identities = 223/628 (35%), Positives = 316/628 (50%), Gaps = 46/628 (7%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EA+TNL A V +L +K S NWM AA GE L ++I GKD Sbjct: 741 EAITNLCAAPVQTLDSIKLSANWMAAAGHAGEDALLYDAVRAVGMELCPALELSIPVGKD 800 Query: 180 SLSMAAQCD-----------------------------GELVKA--PGNLVISAYVTCPD 266 SLSM AQ GE +K+ P +L+ISA+ D Sbjct: 801 SLSMQAQWQVGNGESGIGNGETPAPSASAIPDSRLPIPGETLKSVSPVSLIISAFAPVSD 860 Query: 267 ITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQ------AFDQIGNDCPDIEDVPYL 428 + +TP L+ + L + L GK+RLG S LAQ A G + PD++D L Sbjct: 861 VRTQLTPLLQREDESELWLIGLGGGKQRLGGSVLAQVYADDSALPAFGGETPDLDDPQRL 920 Query: 429 KKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE 608 ++ FE++++ L+ A HD SDGG + EMAFA G+++ ++ +D ++LF E Sbjct: 921 RQFFELIRDAREGGLLLAYHDRSDGGAFAALCEMAFASRQGLDITLDAWGDDAFRSLFNE 980 Query: 609 ELGLVIEVHLDD----LDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDL 776 ELG V+++ +D D+V++ HA A I T P + + G V + R L Sbjct: 981 ELGAVVQIANEDRAAFADLVER--HALTECAQRIARPTGTPRVRVSGQGRVLAEWRWEAL 1038 Query: 777 RDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPLWH--LSFTP-KFTDKKLLSASSKPK 947 D W + +++L+ E+ ++ +P L F P + ++ ++PK Sbjct: 1039 FDAWWSVTHAMQKLRDNPDSADEERAVARNFQAPGLRPKLVFDPSEDVAAPFVATGARPK 1098 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 VAI+RE+G N EM+ F AGF +D+ MSDL+ + L +F G A GGFSY DVL Sbjct: 1099 VAILREQGVNGQIEMAYNFERAGFRAFDVHMSDLIEGRVDLAQFAGFAACGGFSYGDVLG 1158 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMA-LLGWVPGPDIGGSLGAGG 1304 + +GWA SI L F F+ R DTF+LGVCNGCQ+++ L +PG + Sbjct: 1159 AGRGWATSILERAALRDAFAAFFARSDTFALGVCNGCQMLSQLKDIIPGAE--------- 1209 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLS 1484 PRF N S +FE R + + +SPSI+ +GM GS + + AHGEGRA F + Sbjct: 1210 --HWPRFLRNRSEQFEARTALLEVVESPSILLRGMAGSRIPVAVAHGEGRAEF---DTAV 1264 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMMWQY 1664 D + +A LR+ D V YP NPNGSP GI L S +GR LMPHPER+ Sbjct: 1265 DQAAARVA-LRFIDGDGAVASQYPLNPNGSPDGITGLTSTDGRATILMPHPERTPRSVNL 1323 Query: 1665 PWYPKDWQVEKSGPSPWLRMFQNAREWC 1748 W+P W + SPWLRMF+NAR WC Sbjct: 1324 SWHPAGWGED----SPWLRMFRNARVWC 1347
>Q87DN2:PUR4_XYLFT Phosphoribosylformylglycinamidine synthase - Xylella fastidiosa| (strain Temecula1 / ATCC 700964) Length = 1322 Score = 328 bits (841), Expect = 5e-89 Identities = 218/598 (36%), Positives = 304/598 (50%), Gaps = 17/598 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EA+TNL A V SL+ VK S NWM AA+ GE L I+I GKD Sbjct: 742 EAITNLCAAPVESLSMVKLSANWMAAAEYPGEDALLYDAVKAIGIELCPALDISIPVGKD 801 Query: 180 SLSMAAQCDGELVK----APGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 SLSM ++ G+ +P +LVISA+ D +TP L + L + L GK+ Sbjct: 802 SLSMQSRWQGDGATHTCISPVSLVISAFTPVADARRQLTPLLHHQTNSELWLIALDGGKQ 861 Query: 348 RLGCSALAQ------AFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGL 509 RLG S LAQ A G +CPD++ L+ F ++ + + L+ A HD SDGG Sbjct: 862 RLGGSVLAQVHADSAALPAFGGECPDLDTPETLRAFFALMNDARNAGLLLAYHDRSDGGA 921 Query: 510 IVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSA 689 + EMAFA + G+++ + + L LF EELG +++V + + G++A Sbjct: 922 FAALCEMAFASHLGLDITCDNRTEHLFPHLFNEELGAIVQVADEHRTAFADLVEHHGLTA 981 Query: 690 NV--IGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLK 863 I T AP I ++ + + + L D W + ++ L+ C E+E + Sbjct: 982 YTQRIAHPTTAPSIRVMHNDQCLAQWTWETLFDAWWSVTHAIQRLRDNPECADEEREIAR 1041 Query: 864 SRTSPLWH--LSFTPKF-TDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDI 1034 + T+P LSF P +S +PKVAI+RE+G N EM+ F AGF DI Sbjct: 1042 TFTAPGLKPTLSFDPAADVAMPFISTGIRPKVAILREQGINGHIEMALCFERAGFHSVDI 1101 Query: 1035 TMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTF 1214 M+DL+ + L EF G+A GGFSY DVL + +GWA SI L QF F+ R D F Sbjct: 1102 HMNDLITGRVHLDEFVGLAACGGFSYGDVLGAGRGWATSILERTALRDQFAAFFTRTDRF 1161 Query: 1215 SLGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPS 1391 +LGVCNGCQ+++ L +PG + PRF N S +FE R + + SPS Sbjct: 1162 ALGVCNGCQMLSQLKSMIPGAE-----------HWPRFVRNRSEQFEARTALLEVIQSPS 1210 Query: 1392 IMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNG 1571 I GM GS L + AHGEG A F + +D +++A LRY + YP NPNG Sbjct: 1211 IFLSGMAGSRLPVAVAHGEGYAMF---DTPADQAAAHVA-LRYINGHGQAATHYPLNPNG 1266 Query: 1572 SPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 SP GI L + +GR LMPHPER+ W P +W + +PWLR+F+NAR W Sbjct: 1267 SPNGITGLTTTDGRITILMPHPERTPRTINLSWCPNEWGED----APWLRLFRNARAW 1320
>Q9PDF6:PUR4_XYLFA Phosphoribosylformylglycinamidine synthase - Xylella fastidiosa| Length = 1322 Score = 324 bits (830), Expect = 1e-87 Identities = 218/598 (36%), Positives = 303/598 (50%), Gaps = 17/598 (2%) Frame = +3 Query: 3 EALTNLVWAKVTSLADVKASGNWMYAAKIDGEGXXXXXXXXXXXXXXIQ-LGIAIDGGKD 179 EA+TNL A V SL+ VK S NWM AA+ GE L I+I GKD Sbjct: 742 EAITNLCAAPVESLSMVKLSANWMAAAEHPGEDALLYDAVKAIGIELCPALDISIPVGKD 801 Query: 180 SLSMAA--QCDG--ELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKR 347 SLSM + Q DG +P +LVISA+ D +TP L + L + L GK+ Sbjct: 802 SLSMQSRWQADGATHTCISPVSLVISAFTPVADARRQLTPLLHHQTNSELWLIALDGGKQ 861 Query: 348 RLGCSALAQ------AFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGL 509 RLG S LAQ A G +CPD++ L+ F ++ + + L+ A HD SDGG Sbjct: 862 RLGGSVLAQVHADSAALPTFGGECPDLDTPETLRAFFALMNDARNAGLLLAYHDRSDGGA 921 Query: 510 IVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSA 689 + EMAFA + G+++ + + L LF EELG +++V + + G++A Sbjct: 922 FAALCEMAFASHLGLDITCDNRTEHLFPHLFNEELGAIVQVADEHRTAFTDLVEQHGLTA 981 Query: 690 NV--IGEVTAAPEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLK 863 I T AP I ++ + + + L D W + ++ L+ C E+E + Sbjct: 982 YTQRIAHPTTAPSIRIMHNDQCLAQWTWETLFDAWWSVTHAMQRLRDNPECADEEREIAR 1041 Query: 864 SRTSPLWH--LSFTPKF-TDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDI 1034 + T+P LSF P ++ +P VAI+RE+G N EM+ F AGF DI Sbjct: 1042 TFTAPGLKPTLSFDPAVDVAMPFIATGIRPTVAILREQGINGHIEMALCFERAGFHCVDI 1101 Query: 1035 TMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTF 1214 M+DL+ + L EF G+A GGFSY DVL + +GWA SI L QF F+ R D F Sbjct: 1102 HMNDLITGRVHLDEFVGLAACGGFSYGDVLGAGRGWATSILERTALRDQFAAFFTRTDRF 1161 Query: 1215 SLGVCNGCQLMA-LLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPS 1391 +LGVCNGCQ+++ L +PG + PRF N S +FE R + + SPS Sbjct: 1162 ALGVCNGCQMLSQLKSMIPGAE-----------HWPRFVRNRSEQFEARTALLEVIQSPS 1210 Query: 1392 IMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNG 1571 I GM GS L + AHGEG A F + +D +++A LRY + YP NPNG Sbjct: 1211 IFLSGMAGSRLPVAVAHGEGYAMF---DTPADQAAAHVA-LRYINGHGQAATHYPLNPNG 1266 Query: 1572 SPLGIAALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 SP GI L + +GR LMPHPER+ W P +W + +PWLR+F+NAR W Sbjct: 1267 SPNGITGLTTTDGRITILMPHPERTPRTINLSWSPNEWGED----TPWLRLFRNARAW 1320
>P03179:VP14_EBV Probable membrane antigen P140 - Epstein-Barr virus (strain B95-8)| (HHV-4) (Human herpesvirus 4) Length = 1318 Score = 141 bits (356), Expect = 9e-33 Identities = 146/510 (28%), Positives = 225/510 (44%), Gaps = 21/510 (4%) Frame = +3 Query: 279 VTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQEL 458 +TP L+ K G LL + G S Q F + P + LK +F VQ+L Sbjct: 816 ITPVLQ--KTGSLLIAVRCGDGKIQGGSLFEQLFSDVATT-PRAPEALSLKNLFRAVQQL 872 Query: 459 LSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHL 638 + ++ +GHDISDGGL+ ++EMA AG GV + + + +D L +FAE GLV EV Sbjct: 873 VKSGIVLSGHDISDGGLVTCLVEMALAGQRGVTITMPVA-SDYLPEMFAEHPGLVFEVEE 931 Query: 639 DDLDVVKQKLHAAGVSANVIGEV-TAAPE--IELLVDGEVRLKERTSDLRDLWEETSFQL 809 + V Q L + + V+G V P+ E+ E L++ L W +SF Sbjct: 932 RSVGEVLQTLRSMNMYPAVLGRVGEQGPDQMFEVQHGPETVLRQSLRLLLGTW--SSFAS 989 Query: 810 EELQ-----RLKSCVKLEKEGLKS--RTSPLWHLSFTPKFTDKKLLSASSKPKVAIIREE 968 E+ + R+ + + G SPL + +P+ + + + +VA++ Sbjct: 990 EQYECLRPDRINRSMHVSDYGYNEALAVSPLTGKNLSPR---RLVTEPDPRCQVAVLCAP 1046 Query: 969 GSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAA 1148 G+ + AAF AG + + + L ++ G+A G D + + A Sbjct: 1047 GTRGHESLLAAFTNAGCLCRRVFFRE-VRDNTFLDKYVGLAIGGVHGARDSALAGRATVA 1105 Query: 1149 SIRFNQPLIQQFQEFYNRPDTFSLGVCN-GCQLMALLGWVPGPDIGGSLGAGGDMSQPR- 1322 I L +F NRPDTFS+ + G Q++A LG V D + G ++ + Sbjct: 1106 LINRFPALRDAILKFLNRPDTFSVALGELGVQVLAGLGAVGSTDNPPAPGVEVNVQRSPL 1165 Query: 1323 -FTHNESGRFECRFISVAI-GDSPSIMFKGMEGSTLGIW-SAHGEGRAFFPDGNVLSDVV 1493 N SG FE R+++++I + S+M +G+ G L W G F N+ V Sbjct: 1166 ILAPNASGMFESRWLNISIPATTSSVMLRGLRGCVLPCWVQGSCLGLQF---TNLGMPYV 1222 Query: 1494 KSNLAPLRYCDDANNVTEV------YPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMM 1655 N + C +N T+ YP NP IA LCS +GRHLAL+ P Sbjct: 1223 LQNAHQIA-CHFHSNGTDAWRFAMNYPRNPTEQG-NIAGLCSRDGRHLALLCDPSLCTDF 1280 Query: 1656 WQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 WQ+ P + +G SPW MFQ A W Sbjct: 1281 WQWEHIPPAFG-HPTGCSPWTLMFQAAHLW 1309
>P11282:VP75_SHV21 Probable membrane antigen 75 - Saimiriine herpesvirus 2 (strain 11)| (SaHV-2) (Herpesvirus saimiri) Length = 1299 Score = 136 bits (343), Expect = 3e-31 Identities = 141/529 (26%), Positives = 226/529 (42%), Gaps = 20/529 (3%) Frame = +3 Query: 222 APGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFDQIGNDC 401 A +V++A I +TP LK ++ L+HV L+K + L S +F + Sbjct: 795 AANTVVVTASARVTSIE-RITPALKKAENA-LVHVCLSK-ELTLSGSVFENSFTAFSSHL 851 Query: 402 PDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDN 581 PD+ D L+ +F V+ L+S+ L+ AGHDISDGGLI T EM FA GV +N+ Sbjct: 852 PDL-DTSKLRDMFYAVKHLISKNLVVAGHDISDGGLITTAAEMCFASTFGVTVNLP-SAL 909 Query: 582 DLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKE 761 L L +E G ++EV + L V L G++ +G V + + +G L E Sbjct: 910 PALMYLVSETPGALLEVPKEHLSTVTTLLSERGLTWYAVGTVNNVKNLSIYDNGTHLLTE 969 Query: 762 RTSDLRDLWEETSFQLEELQRLKSCVK-LEKEGLKSRTSPLWHLSFTPKFTDKKLLSASS 938 + L W S+ E + + ++ + + + L HL +L + S Sbjct: 970 SINILNSKW--MSYAEESFETCEPHIESMYRNDYGNNAMDLKHLEDLCTHKPLQLYTCPS 1027 Query: 939 KP-KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYA 1115 P VA++ G AF GF + I+ ++ L Q +L F +A G ++ Sbjct: 1028 HPVSVAVLTFPGCPDPVATLQAFANVGFLSYPIS-TEFLLQGNNLNAFSCLAVSGSSAFE 1086 Query: 1116 DVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN--GCQLMALLGWVPGPDIGGS 1289 + + ++ +EF+ RPDT SL C G QL+A +G + Sbjct: 1087 EEGTGTRIAIYTLLQCDLAKNCLKEFFQRPDTLSL-CCGELGTQLLAAC-----QVVGDT 1140 Query: 1290 LGAGGDMSQP------RFTHNESGRFECRFISVAIGD-SPSIMFKGMEGSTL--GIWSAH 1442 + GD+S N S +E +++ + + SI+ + + G+ G+W Sbjct: 1141 HPSRGDISSNPESWTLELEPNASKHYESLWLNFHVPQTTKSIILQALRGTIFQDGLWQVL 1200 Query: 1443 G-------EGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCS 1601 G + +G + + + P Y YP NP+G+ +A +CS Sbjct: 1201 GLRYKHDAQEYIMQQNGTIAMSYHSAKINPYLYAMH-------YPRNPSGNS-SVAGICS 1252 Query: 1602 PNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREWC 1748 NGRHLAL+ P SF WQ+ PK SPW M+Q WC Sbjct: 1253 KNGRHLALLVEPALSFHTWQWQHIPKPLVT-----SPWALMYQCMFLWC 1296
>Q6M0U0:PURQ_METMP Phosphoribosylformylglycinamidine synthase 1 - Methanococcus| maripaludis Length = 272 Score = 130 bits (327), Expect = 2e-29 Identities = 87/255 (34%), Positives = 123/255 (48%), Gaps = 3/255 (1%) Frame = +3 Query: 942 PKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 PKV ++ G N + E + AF AG E + ++DL+ K + ++ I F GGFSY D Sbjct: 6 PKVLVMSGYGINCETETAHAFQKAGAETDIVHINDLIAGKKKMADYEIIMFPGGFSYGDD 65 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGW--VPGPDIGGSLG 1295 S +A I+ N L EF N LG+CNG Q+M LG +P D G + Sbjct: 66 TGSGNAFANKIKNN--LFDDLTEFINSGKLI-LGICNGFQVMTNLGLFALPSTDYGERIS 122 Query: 1296 AGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGN 1475 A N + R+ECR++ + DS + KG+ + + I AHGEGR F+ D Sbjct: 123 A--------LESNTNNRYECRWVHIKENDSVCVFTKGINVTHVPI--AHGEGR-FYCDEK 171 Query: 1476 VLSDVVKSNLAPLRYCD-DANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFM 1652 ++ ++ YCD + N YP NPNG+ IA +C GR LMPHPERS Sbjct: 172 TYHELKENKQIVFSYCDSEGNPANGEYPLNPNGAYQDIAGICDKTGRIFGLMPHPERSLY 231 Query: 1653 MWQYPWYPKDWQVEK 1697 P Y ++ K Sbjct: 232 SISEPEYQLKKEIAK 246
>Q01000:VP03_SHV21 Probable membrane antigen 3 - Saimiriine herpesvirus 2 (strain 11)| (SaHV-2) (Herpesvirus saimiri) Length = 1246 Score = 129 bits (324), Expect = 5e-29 Identities = 124/533 (23%), Positives = 226/533 (42%), Gaps = 10/533 (1%) Frame = +3 Query: 177 DSLSMAAQCDGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKRRLG 356 ++L ++ + ++V SA V D++ +TPDLK + L + K G Sbjct: 725 EALRVSCTFTANATEGGASIVASAIVNTLDVSKCITPDLKFNNSFLFL-LTTEKDYSLFG 783 Query: 357 CSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAF 536 A + P LKK+ V+Q L+ + + +GHD+SDGGL+ T+ EMA Sbjct: 784 SVAQQILEKTFIGEIPSATSPVMLKKMLSVLQTLIKDESVVSGHDVSDGGLVATVAEMAL 843 Query: 537 AGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAA 716 +G GV + + D ++ L +E G+VIEV + V+Q LH+ ++ +IGE T++ Sbjct: 844 SGGKGVRVYVP-HGEDAIKFLCSETPGVVIEVQGSKMYYVQQFLHSENINFQIIGESTSS 902 Query: 717 PEIELLVDGEVRLKERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPLWHLSF 896 + + + E + W S E Q +++ ++ Sbjct: 903 LTFSISQNLTKLVHEPLELFKSAWRSFSDACEPCQIHPRPYRMQ-------------IAT 949 Query: 897 TPKFTDKKLLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTE 1076 PK+ + V + ++ + A AGF+P ++ ++Q + T Sbjct: 950 VPKYCP---VGPCRFHTVIVYLLPNNSVPHGLLNAIEEAGFQPRLVS----IHQPSKTTN 1002 Query: 1077 FR------GIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGV-CNG 1235 G VG + D + A ++ + + + +PD FS+ + Sbjct: 1003 VYDPHTVWGFFIVGASNVQDEDVGMRALIAQLKSHVAFQRDLRTMLAKPDVFSVAIGALA 1062 Query: 1236 CQLMALLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDS-PSIMFKGME 1412 C+L+ IG + + M+ N S +FE R+ ++ I +S +I F+ ++ Sbjct: 1063 CELLFY-----NKAIGYNKPSDTYMT---CVKNSSRKFESRWSNIYIPESTKAIAFQSLK 1114 Query: 1413 GSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDD--ANNVTEVYPFNPNGSPLGI 1586 S + W+ G F+ +L + +S + + ++ + YP PNG I Sbjct: 1115 NSLIPCWT-QGTHLKFYHPKPMLEKMEESGMVSSMFYGHSLSSGPAQNYPLTPNGEN-AI 1172 Query: 1587 AALCSPNGRHLALMPHPERSFMMWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 A +CS +GRHLAL+ P +WQ+P+ P + K SPW MF + +W Sbjct: 1173 AGVCSADGRHLALLHDPSLCNNLWQWPYVPLENPPLK--VSPWKTMFLDLHKW 1223
>Q3Z9H5:PURQ_DEHE1 Phosphoribosylformylglycinamidine synthase 1 - Dehalococcoides| ethenogenes (strain 195) Length = 255 Score = 126 bits (316), Expect = 4e-28 Identities = 89/271 (32%), Positives = 135/271 (49%), Gaps = 1/271 (0%) Frame = +3 Query: 936 SKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYA 1115 SK K I+R G+N D E S AF AG E + +++LL + + L EF+ +AF GGF Y Sbjct: 2 SKVKTLILRTPGTNCDIETSYAFELAGSETEMVHINELLAKPSRLAEFQIMAFPGGFGYG 61 Query: 1116 DVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLG 1295 D L + + A +R L ++ F+ +G+CNG Q + G +PGP G Sbjct: 62 DDLGAGRVLANEVRLK--LGEKINRFHESGGLI-IGICNGFQALVKTGILPGPMKDG--- 115 Query: 1296 AGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMF-KGMEGSTLGIWSAHGEGRAFFPDG 1472 + T N SGRFECR+ +A+ + +F +G++ L + AHGEG+ Sbjct: 116 -----QKITLTENNSGRFECRWTYLAVNPFSTCVFTQGIDRLYLPV--AHGEGKLLGS-- 166 Query: 1473 NVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFM 1652 +V+ + + Y D YP NP G+ + IA + +GR ALMPHPER Sbjct: 167 ---PEVINKLNSVVYYTDKDGKRNSPYPANPAGTLMDIAGIADESGRIFALMPHPERFVR 223 Query: 1653 MWQYPWYPKDWQVEKSGPSPWLRMFQNAREW 1745 Q+P +P + E+ L++F NA +W Sbjct: 224 GSQHPRWPAEGLKEE---GDGLKIFTNAVKW 251
>Q73MV2:PURQ_TREDE Phosphoribosylformylglycinamidine synthase 1 - Treponema denticola| Length = 270 Score = 117 bits (292), Expect = 2e-25 Identities = 76/246 (30%), Positives = 120/246 (48%), Gaps = 7/246 (2%) Frame = +3 Query: 939 KPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYAD 1118 KP+ ++ G+N D + + A AG EP + ++ L ++ + ++ + GGFSYAD Sbjct: 2 KPRALVLHATGTNRDGDAARALELAGAEPEIVHINKLKAKEKNWKDYEILVIPGGFSYAD 61 Query: 1119 VLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 L + K +A + + + EF +G+CNG Q++ G +PG + G + Sbjct: 62 ALGAGKLFALDL--SNYFFDEVSEFVAAGKPV-IGICNGFQVLVKSGILPGKEKDGKVIL 118 Query: 1299 GGD---MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPD 1469 D Q T+N+ GRFECRF ++ S I K ++G+ + AHGEGR Sbjct: 119 DKDGYKNRQATLTYNKQGRFECRFTTMIPQKSNCIWTKDLKGN-IHCPIAHGEGRFLTDS 177 Query: 1470 GNVLSDVVKSNLAPLRY----CDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHP 1637 L D+ + L Y + + YPFNPNGS IA +C+ G L LMPHP Sbjct: 178 QKTLDDLFEKGQIALVYGGKDAEKSIPANGEYPFNPNGSLADIAGICNTKGNVLGLMPHP 237 Query: 1638 ERSFMM 1655 E + ++ Sbjct: 238 ENNVVI 243
>Q6L0V9:PURQ_PICTO Phosphoribosylformylglycinamidine synthase 1 - Picrophilus torridus| Length = 248 Score = 115 bits (287), Expect = 9e-25 Identities = 74/239 (30%), Positives = 124/239 (51%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 + ++R EG+N++ E + AGFEP + ++DL ++ + ++ + GGFS D + Sbjct: 5 RAMVLRMEGTNNEEEAFLSLKRAGFEPEYVHINDLARKRKFIDDYNLMFIPGGFSAGDYI 64 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + +AA +R P + +F + F +GVCNG Q++ LG L G Sbjct: 65 RAGAIFAARLR---PFLSDINKFIDS-GRFIIGVCNGFQVLTELG----------LFFNG 110 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLS 1484 D + T NES RFECRF + + S + G+ + AH EGR + D L Sbjct: 111 DR-KIALTVNESNRFECRFTYIRL--STKKVLSGLGNRPFQVPVAHLEGRVYC-DNKTLD 166 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMMWQ 1661 ++++++ RY D+ N + YP+NPNGS + IA + + +G + +MPHPER + +Q Sbjct: 167 ELIENDQIIFRYVDNNGNYSG-YPWNPNGSIMNIAGITNDSGNVIGMMPHPERVYYPYQ 224
>O29008:PURQ_ARCFU Phosphoribosylformylglycinamidine synthase 1 - Archaeoglobus fulgidus| Length = 271 Score = 111 bits (277), Expect = 1e-23 Identities = 79/248 (31%), Positives = 121/248 (48%), Gaps = 9/248 (3%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITM----SDLLN--QKASLTEFRGIAFVGGF 1106 KVA++R EG+N + E AF + G E + + SD++ ++ S+ +++ + F GGF Sbjct: 7 KVAVLRMEGTNCEDETVKAFRSLGVEAEAVHIKQFYSDMIRFEEQRSVFDYQCLVFPGGF 66 Query: 1107 SYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGG 1286 S D + + G S R L + +EF LG+CNG Q++ LG +PG D Sbjct: 67 SAGDYIRA--GAIFSARVKSVLRKDIEEFIKMGYPI-LGICNGFQVLVELGALPGFDEDK 123 Query: 1287 SLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFP 1466 L +M+ N+S RFECR + I K ++ + AH EG+ FP Sbjct: 124 PLAEKPEMA---LAMNDSSRFECRPTLLKKESEKCIFVKNLKKDVVMFPVAHAEGKVVFP 180 Query: 1467 DGN---VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHP 1637 G L + ++ RY D+ + YP+NPNGS IA +C+ LMPHP Sbjct: 181 SGKEDEYLERLTSNDQIVFRYVDEKGDYAG-YPWNPNGSFYNIAGICNATHTVFGLMPHP 239 Query: 1638 ERSFMMWQ 1661 ER+F +Q Sbjct: 240 ERAFFGYQ 247
>Q97C36:PURQ_THEVO Phosphoribosylformylglycinamidine synthase 1 - Thermoplasma volcanium| Length = 258 Score = 110 bits (275), Expect = 2e-23 Identities = 73/243 (30%), Positives = 127/243 (52%), Gaps = 3/243 (1%) Frame = +3 Query: 942 PKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 PK+ I+ EG+N++ E+ + +G P I ++DL + ++++ G+ GGFS D Sbjct: 5 PKIGILLMEGTNNETEVYYSVKRSGGSPDFIHINDLSAGRKRVSDYDGLIIPGGFSAGDY 64 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 + + +AA R ++ +EF + +G+CNG Q++ +G + Sbjct: 65 IRAGVIFAA--RLGAVAGKEIREFVDDGKPL-IGICNGFQVLMEMGLIY----------- 110 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS---AHGEGRAFFPDG 1472 D S+ T+NES RFECR+ + + I G G G++ AH EGR + Sbjct: 111 -DRSKITLTNNESNRFECRYTYMKMTSRNRIFQSGFYGK--GVFQVPVAHAEGRIAVSER 167 Query: 1473 NVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFM 1652 +VL + +++ +Y ++ N+VT+ YP+NPNGS +A+L + G + LMPHPER + Sbjct: 168 SVLKKLYENDQVVFKYSNE-NDVTDEYPWNPNGSIDSVASLSNEAGNVIGLMPHPERIYY 226 Query: 1653 MWQ 1661 +Q Sbjct: 227 RYQ 229
>Q9HIM1:PURQ_THEAC Phosphoribosylformylglycinamidine synthase 1 - Thermoplasma| acidophilum Length = 257 Score = 109 bits (273), Expect = 4e-23 Identities = 72/243 (29%), Positives = 127/243 (52%), Gaps = 3/243 (1%) Frame = +3 Query: 942 PKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 PKV I+ EG+N++ E+ + +G +P + +SD+ + +++++ + GGFS D Sbjct: 4 PKVGILLMEGTNNETEVFFSVRRSGGDPDYVHVSDIAAGRKAISDYDALIVPGGFSAGDY 63 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYN--RPDTFSLGVCNGCQLMALLGWVPGPDIGGSLG 1295 + + +AA R ++ ++F + RP +G+CNG Q++ +G + Sbjct: 64 IRAGVIFAA--RLLAVAGKEIRDFVDSGRP---LIGICNGFQVIMEMGLI---------- 108 Query: 1296 AGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGS-TLGIWSAHGEGRAFFPDG 1472 G + T+NESGRFECR+ + + I +G + + AH EGR Sbjct: 109 --GKRDELTLTNNESGRFECRYTYITMTSDNPIFRDAFKGKGSFQVPVAHAEGRIAVSGV 166 Query: 1473 NVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFM 1652 +VL + +++ +Y D + VT+ YP+NPNGS IA+L + +G + LMPHPER + Sbjct: 167 SVLKRLYENDQVLFKY-SDTHGVTDEYPWNPNGSVDSIASLTNEHGNVIGLMPHPERIYY 225 Query: 1653 MWQ 1661 +Q Sbjct: 226 SYQ 228
>Q5JFP4:PURQ_PYRKO Phosphoribosylformylglycinamidine synthase 1 - Pyrococcus| kodakaraensis (Thermococcus kodakaraensis) Length = 223 Score = 99.8 bits (247), Expect = 4e-20 Identities = 77/235 (32%), Positives = 113/235 (48%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ G+N D E A AG E ++ + K SL +F G+ GGFSYAD L Sbjct: 3 KFAVVVFPGTNCDFETERAIRKAGAE------AERVWYKTSLKDFDGVVLPGGFSYADYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I Q +I++ +EF R LG+CNG Q++ G +PG Sbjct: 57 R-----AGAIAARQEIIEEVKEFA-RDGKPVLGICNGFQVLTEAGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 N+ RF CR++ + + D+ + + E G + + AH EG + D + Sbjct: 101 ------LRPNKVPRFICRWVHLRVADTETPFTQFYEPGEVIRMPIAHAEGNYYADDPS-- 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 K +A +Y D+ N+TE NPNGS L IAA+ + NG L MPHPER+ Sbjct: 153 ----KVRIA-FQYSDEEGNITE--EANPNGSLLNIAAIANENGNVLGTMPHPERA 200
>Q59042:PURQ_METJA Phosphoribosylformylglycinamidine synthase 1 - Methanococcus| jannaschii Length = 230 Score = 98.6 bits (244), Expect = 9e-20 Identities = 70/235 (29%), Positives = 113/235 (48%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K+A+ + G+N D ++ A AG EP + + + +L ++G GGFSY D L Sbjct: 2 KIAVTKFLGTNCDLDVCHAVKLAGGEPELVFFT-----QENLDSYKGAVIPGGFSYGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I P+I+ ++ LG+CNG Q+ G Sbjct: 57 R-----AGAISARTPIIKGLKKMVEEGKPV-LGICNGAQI----------------GLEA 94 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 S+ T+N + +F C+++ + + ++ + + + G L I AH EGR F+ D L Sbjct: 95 GFSKGTLTNNLNAKFICKWVYIRVENNKTPFTQYYKKGEVLKIPIAHAEGR-FYADDETL 153 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + K+N+ +YCD+ VTE NPNGS IA +C+ N + LMPHPER+ Sbjct: 154 DYMYKNNMIVFKYCDETGEVTE--EANPNGSIDNIAGVCNENQNCVLLMPHPERA 206
>Q9UXW5:PURQ_PYRAB Phosphoribosylformylglycinamidine synthase 1 - Pyrococcus abyssi| Length = 223 Score = 91.7 bits (226), Expect = 1e-17 Identities = 73/238 (30%), Positives = 113/238 (47%), Gaps = 3/238 (1%) Frame = +3 Query: 942 PKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 P+ A+I G+N D E A AG E ++ + K S+ E+ G+ GGFSYAD Sbjct: 2 PRFAVIVFPGTNCDFETVEAIRKAGGE------AERVWYKESIREYDGVVLPGGFSYADY 55 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYN--RPDTFSLGVCNGCQLMALLGWVPGPDIGGSLG 1295 L A +I Q ++++ +EF RP LG+CNG Q++ G +PG Sbjct: 56 LR-----AGAIAARQRIMEEVREFAEEGRP---VLGICNGFQVLTEAGLLPGA------- 100 Query: 1296 AGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDG 1472 N+ RF C++I + + D+ + + E G + + AH EG + D Sbjct: 101 ---------LRPNKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDP 151 Query: 1473 NVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + V +Y D+ N+TE NPNGS + IA + + G L +MPHPER+ Sbjct: 152 SRIRIV-------FQYSDENGNLTE--EANPNGSVMNIAGVSNEGGNVLGMMPHPERA 200
>Q18FM4:PURQ_HALWD Phosphoribosylformylglycinamidine synthase 1 - Haloquadratum walsbyi| (strain DSM 16790) Length = 228 Score = 91.3 bits (225), Expect = 1e-17 Identities = 72/234 (30%), Positives = 103/234 (44%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 V +++ GSN DR+ A G + + D LN S+ GI GGFSY D L Sbjct: 3 VVVVQFGGSNCDRDAVRALQHIGIDATRVWHEDGLND--SVENLDGIILPGGFSYGDYLR 60 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A ++ + P++ Q R LGVCNG Q+ G PG Sbjct: 61 -----AGAMAAHSPIVNDIQAAAERGIPV-LGVCNGAQVGCESGLTPGA----------- 103 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVLS 1484 FT N+ RF+C + + + ++ + + E G+ + I AHGEGR F N Sbjct: 104 -----FTTNDRARFQCETVHLRVENATTPWTEAYEAGTVIEIPIAHGEGR-FEITENEYE 157 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + N RYCD + N+T+ NPNGS +A + LMPHPER+ Sbjct: 158 MLKNDNQILFRYCDASGNITD--DANPNGSRGNVAGITGNYDTVAVLMPHPERA 209
>Q3IMR2:PURQ_NATPD Phosphoribosylformylglycinamidine synthase 1 - Natronomonas pharaonis| (strain DSM 2160 / ATCC 35678) Length = 224 Score = 90.9 bits (224), Expect = 2e-17 Identities = 73/234 (31%), Positives = 104/234 (44%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 VAIIR GSN DR+ A DI + ++ E G+ GGFSY D L Sbjct: 3 VAIIRFGGSNCDRDAERALAHL-----DIDAEIVWHEDGLPEETTGVMIPGGFSYGDYLR 57 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A ++ P++ +E LGVCNG Q+ G+ GD Sbjct: 58 -----AGAMAARAPIMDDVRE-QAEAGVPVLGVCNGAQI----------------GSEGD 95 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVLS 1484 ++ FT N S RF+C + + + ++ + + E G + + AHGEGR D L Sbjct: 96 LTPGAFTTNRSARFQCEPVYLRVENAETPWTEAYEDGEVIEVPIAHGEGRFEIADDE-LE 154 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +V + RYCD NVT+ NPNGS +A + + LMPHPER+ Sbjct: 155 TLVDEDRVIFRYCDADGNVTDAA--NPNGSKDNVAGVLGEHESVAVLMPHPERA 206
>Q8TX85:PURQ_METKA Phosphoribosylformylglycinamidine synthase 1 - Methanopyrus kandleri| Length = 226 Score = 89.4 bits (220), Expect = 5e-17 Identities = 78/272 (28%), Positives = 119/272 (43%), Gaps = 4/272 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 +VA+IR G+N D EM+ A AG +P + D L +F + GGF+Y D + Sbjct: 3 RVAVIRFPGTNCDLEMAWAVKLAGGDPEFVWHED-----GGLDDFDAVIIPGGFTYGDYI 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYN--RPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 A +I P++++ +E RP LGVCNG Q++A +PG Sbjct: 58 R-----AGAIAALSPILEEIRECAEDGRP---VLGVCNGMQILAEAELIPGT-------- 101 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIG--DSPSIMFKGMEGSTLGIWSAHGEGRAFFPDG 1472 T N RF C ++ + + D+P K E + + AH EGR ++ + Sbjct: 102 --------LTVNVGNRFICDWVYLRVERTDTP-FTTKYQEDEVIRVPIAHAEGRYYYENP 152 Query: 1473 NVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFM 1652 + D V R+C +V+E Y N NGS GI + + +G L +MPHPER+ Sbjct: 153 EEIEDNVV-----FRFCGPDGDVSEEY--NLNGSVGGITGVVNDDGNVLGMMPHPERA-- 203 Query: 1653 MWQYPWYPKDWQVEKSGPSPWLRMFQNAREWC 1748 LR+F++ EWC Sbjct: 204 -----------AHRLLNSDDGLRLFESLVEWC 224
>Q1GGM0:PURQ_SILST Phosphoribosylformylglycinamidine synthase 1 - Silicibacter sp.| (strain TM1040) Length = 222 Score = 88.6 bits (218), Expect = 9e-17 Identities = 70/236 (29%), Positives = 105/236 (44%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYADV 1121 K A++ GSN DR+++ AF AGF+ +S + ++ + L E I V GGFSY D Sbjct: 2 KAAVVVFPGSNCDRDLAVAFEQAGFD-----VSMVWHKDSELPEGVDIVGVPGGFSYGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P+ + R ++LGVCNG Q++ G +PG Sbjct: 57 LR-----CGAIAAQSPICKAVVAHAERGG-YALGVCNGFQILTETGVLPGA--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNV 1478 N ++ C+ + +A+ S S +G G +G+ AH +G + D V Sbjct: 102 -------LLRNAGLKYICKTVDLAVATSDSAFTQGYNAGDVIGVPIAHHDGNYYADDATV 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + D + V Y NPNGS IA + S N R L +MPHPER+ Sbjct: 155 ------------QMLKDQDRVAFTYVDNPNGSVADIAGILSENRRVLGMMPHPERA 198
>Q31B97:PURQ_PROM9 Phosphoribosylformylglycinamidine synthase 1 - Prochlorococcus| marinus (strain MIT 9312) Length = 221 Score = 88.2 bits (217), Expect = 1e-16 Identities = 74/234 (31%), Positives = 105/234 (44%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 V ++ GSN DR++S A DI L ++ + L++ I GGFSY D L Sbjct: 6 VGVVVFPGSNCDRDVSWALEGC----LDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYLR 61 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF+ PLI EF LG+CNG Q++ G++PG + Sbjct: 62 CG----AIARFS-PLINALDEFVKSGKRV-LGICNGFQILTESGFLPGALVA-------- 107 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFK-GMEGSTLGIWSAHGEGRAFFPDGNVLS 1484 N++ F C + + I + F G E T+ + AHGEGR + D + L Sbjct: 108 --------NKNLNFICDDVELDIVSTKGGWFNNGDEKQTIKLPIAHGEGR-YHCDSDTLK 158 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +V + L LRY + NPNGS IA + + G L LMPHPER+ Sbjct: 159 KLVDNELIALRYKN-----------NPNGSSFDIAGITNEKGNVLGLMPHPERA 201
>Q2S567:PURQ_SALRD Phosphoribosylformylglycinamidine synthase 1 - Salinibacter ruber| (strain DSM 13855) Length = 235 Score = 85.9 bits (211), Expect = 6e-16 Identities = 73/226 (32%), Positives = 108/226 (47%), Gaps = 1/226 (0%) Frame = +3 Query: 969 GSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAA 1148 GSN D + A+HAA + +D + +++ASL + + GGFSY D L S A Sbjct: 12 GSNCDHD---AYHAA-HDVFDQEARFIWHEEASLGDVDVVIVPGGFSYGDYLRSG----A 63 Query: 1149 SIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDMSQPRFT 1328 RF+ P++Q F G+CNG Q++ G +PG Sbjct: 64 VARFS-PIMQDVVRFAE-DGGLVFGICNGFQVLCEAGLLPGT----------------LM 105 Query: 1329 HNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNL 1505 NES RF C+ + + ++ + + EG + I +HGEGR ++ D +VL+ + ++ Sbjct: 106 RNESLRFVCKDTPLRVENAGTPFTNALTEGQVITIPVSHGEGR-YYADEDVLARIEANDQ 164 Query: 1506 APLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPER 1643 LRY VT+ NPNGS GIA L + G LMPHPER Sbjct: 165 VLLRYSTADGAVTD--EANPNGSVHGIAGLVNEAGNVCGLMPHPER 208
>Q9HNU2:PURQ_HALSA Phosphoribosylformylglycinamidine synthase 1 - Halobacterium| salinarium (Halobacterium halobium) Length = 224 Score = 84.7 bits (208), Expect = 1e-15 Identities = 71/234 (30%), Positives = 99/234 (42%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 VA++R GSN DR+ A G + D L G+ GGFSY D L Sbjct: 3 VAVVRFGGSNCDRDAVRALAHLGVDAAVAWHDDGLPADTD-----GVVVPGGFSYGDYLR 57 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A ++ P++ + + LGVCNG Q+ G PG Sbjct: 58 -----AGAMAAQSPVVAEVRALA-ADGVPVLGVCNGAQIGCEAGLAPGA----------- 100 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNVLS 1484 FT N S RF+C + + + ++ + EG L I AHGEGR F D + + Sbjct: 101 -----FTTNASARFQCERVHLRVENATTPWTAAYSEGDVLEIPIAHGEGR-FEIDDDAYA 154 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 D+V + RYC+ VTE NPNGS +A + +MPHPER+ Sbjct: 155 DLVADDRVLFRYCNADGEVTEAA--NPNGSTGAVAGVTGDRDHVAVMMPHPERA 206
>O26270:PURQ_METTH Phosphoribosylformylglycinamidine synthase 1 - Methanobacterium| thermoautotrophicum Length = 218 Score = 84.3 bits (207), Expect = 2e-15 Identities = 70/236 (29%), Positives = 112/236 (47%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 +V +IR GSN DR++ AG EP + NQ+ +L + GGFSY D L Sbjct: 2 RVGVIRFPGSNCDRDVHHVLELAGAEPEYVWW----NQR-NLDHLDAVVIPGGFSYGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I P++ +E R + LG+CNG Q++A +G VPG Sbjct: 57 R-----AGAIAAITPVMDAVRELV-REEKPVLGICNGAQILAEVGLVPGV---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM--EGSTLGIWSAHGEGRAFFPDGNV 1478 FT NE +F C++ + + + + F G+ + + + AH EGR + + Sbjct: 101 ------FTVNEHPKFNCQWTELRVKTTRT-PFTGLFKKDEVIRMPVAHAEGRYYHDN--- 150 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +S+V +++ L++ + NPNGS GI +C +G A+MPHPER+ Sbjct: 151 ISEVWENDQVVLQFHGE----------NPNGSLDGITGVCDESGLVCAVMPHPERA 196
>Q8U492:PURQ_PYRFU Phosphoribosylformylglycinamidine synthase 1 - Pyrococcus furiosus| Length = 223 Score = 83.6 bits (205), Expect = 3e-15 Identities = 66/235 (28%), Positives = 106/235 (45%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ G+N D E A AG + + D S+ ++ G+ GGFSYAD L Sbjct: 3 KFAVVVFPGTNCDFETVEAIKRAGGKAERVWYKD------SIKDYDGVVIPGGFSYADYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I Q ++++ +E LG+CNG Q++ G +PG Sbjct: 57 R-----AGAIAARQRIMEEIRELAEEGRPI-LGICNGFQILTEAGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 N+ RF C+++ + + D + + EG + + AH EG + D + + Sbjct: 101 ------LRPNKIPRFLCKWVHLKVVDVRTPFTYLYEEGEVVRMPIAHAEGNYYIDDPSKV 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 V +Y D+ ++TE NPNGS L IA + + G L +MPHPER+ Sbjct: 155 RIV-------FQYSDEKGSITE--EANPNGSVLNIAGVANMEGNILGMMPHPERA 200
>O59619:PURQ_PYRHO Phosphoribosylformylglycinamidine synthase 1 - Pyrococcus horikoshii| Length = 223 Score = 81.6 bits (200), Expect = 1e-14 Identities = 66/235 (28%), Positives = 107/235 (45%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I G+N D E A AG E ++ + K S+ ++ G+ GGFSYAD L Sbjct: 3 KFAVIVFPGTNCDFETVEAIKRAGGE------AERVWYKQSVKDYDGVVIPGGFSYADYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I Q ++++ +E LG+CNG Q++ +PG Sbjct: 57 R-----AGAIAARQKVMEEIRELAEEGRPI-LGICNGFQILTEANLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 N+ RF C+++ + + D + + EG + + AH EG + + + + Sbjct: 101 ------LRPNKIPRFLCKWVHLKVVDVETPFTYLYEEGEVVRMPIAHAEGNYYIDNPSKV 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 V +Y D+ ++TE NPNGS L IA + + G L +MPHPER+ Sbjct: 155 RIV-------FQYSDEKGSITE--EANPNGSVLNIAGVTNKQGNVLGMMPHPERA 200
>Q71YP8:PURQ_LISMF Phosphoribosylformylglycinamidine synthase 1 - Listeria monocytogenes| serotype 4b (strain F2365) Length = 227 Score = 81.3 bits (199), Expect = 1e-14 Identities = 71/237 (29%), Positives = 104/237 (43%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I+ GSN D +M A + E + + + SL F + GGFSY D L Sbjct: 2 KFAVIQFPGSNCDLDMLHAIRDSLGEEAEYVW----HAETSLAGFDAVLLPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + G A P + +F E +P LGVCNG Q++ +G +PG I Sbjct: 58 RT--GAIAKFSSIMPEVLRFAEM-GKP---VLGVCNGFQILTEIGLLPGALI-------- 103 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM--EGSTLGIWSAHGEGRAFFPDGNV 1478 N + F C+ + + + ++ S MF G+ EG + + AHGEG + D + Sbjct: 104 --------RNNNLHFICKTVPLRVANA-STMFTGLYKEGEIIQVPVAHGEGNYYCDDETL 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYP-FNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L D N + Y NPNGS IA + + G L +MPHPER+ Sbjct: 155 LK------------LKDNNQIVFTYDSVNPNGSRADIAGIVNERGNVLGMMPHPERA 199
>Q3AD65:PURQ_CARHZ Phosphoribosylformylglycinamidine synthase 1 - Carboxydothermus| hydrogenoformans (strain Z-2901 / DSM 6008) Length = 234 Score = 80.9 bits (198), Expect = 2e-14 Identities = 59/187 (31%), Positives = 88/187 (47%), Gaps = 1/187 (0%) Frame = +3 Query: 1086 IAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWV 1265 I GGFSY D L + A RF+ P++++ EF N +G+CNG Q++ G + Sbjct: 44 IVLPGGFSYGDYLRAG----AIARFS-PVMKKVVEFANAGGLV-IGICNGFQILLEAGLL 97 Query: 1266 PGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAI-GDSPSIMFKGMEGSTLGIWSAH 1442 PG + N+S F C + + + ++ K EG L I AH Sbjct: 98 PGAML----------------RNKSINFRCHDVYLRVENNNTPFTSKAHEGQVLKIPIAH 141 Query: 1443 GEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLA 1622 GEG ++ + + L ++ + RYC+ VTE NPNGS IA + + G L Sbjct: 142 GEGN-YYCEPDTLKKLIANGQVVFRYCNSRGEVTE--DANPNGSLYNIAGIINEKGNVLG 198 Query: 1623 LMPHPER 1643 +MPHPER Sbjct: 199 MMPHPER 205
>Q7V1S5:PURQ_PROMP Phosphoribosylformylglycinamidine synthase 1 - Prochlorococcus| marinus subsp. pastoris (strain CCMP 1378 / MED4) Length = 221 Score = 80.5 bits (197), Expect = 2e-14 Identities = 70/234 (29%), Positives = 104/234 (44%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 V I+ GSN DR++S A DI L ++ + L + I GGFSY D L Sbjct: 6 VGIVVFPGSNCDRDVSWALEGC----LDIKTKFLWHESSDLNDVDSIVLPGGFSYGDYLR 61 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF+ PLI +F + LG+CNG Q++ G++PG + Sbjct: 62 CG----AIARFS-PLINSLHDFI-KSGRRVLGICNGFQILTESGFLPGALVA-------- 107 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNVLS 1484 N++ F C + + + S F+ + E + + AHGEG + D + L Sbjct: 108 --------NKNLNFICDDVDLNVITSKGGWFQKLNENQNIKLPIAHGEG-CYHCDQDTLK 158 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +V ++L L+Y NPNGS IA + + G L LMPHPER+ Sbjct: 159 RLVDNDLIALKY-----------KTNPNGSTSDIAGITNEKGNVLGLMPHPERA 201
>O67190:PURQ_AQUAE Phosphoribosylformylglycinamidine synthase 1 - Aquifex aeolicus| Length = 227 Score = 80.5 bits (197), Expect = 2e-14 Identities = 55/198 (27%), Positives = 94/198 (47%), Gaps = 1/198 (0%) Frame = +3 Query: 1056 QKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNG 1235 ++ +L+++ + GGFS+ D L ++ PL Q +F + + +G+CNG Sbjct: 35 EEKNLSKYDVVVLPGGFSFGDYLRPG-----ALAARTPLAQAIYDFAQK-GKYVIGICNG 88 Query: 1236 CQLMALLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME- 1412 Q++ LG +PG N + RF C+++++ + + S + +E Sbjct: 89 FQILTELGLLPGA----------------LLPNLNMRFVCKWVNLRVENERSAFTRKLEK 132 Query: 1413 GSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAA 1592 G L I AH +GR + P+ L + ++ RYCD+ V E NPNGS IA Sbjct: 133 GDVLRIPIAHHDGRYYVPEEE-LRKMEENGQILFRYCDEQGEVKE--EVNPNGSVSNIAG 189 Query: 1593 LCSPNGRHLALMPHPERS 1646 + + G +MPHPER+ Sbjct: 190 VMNKEGNVFGMMPHPERA 207
>Q5SI57:PURQ_THET8 Phosphoribosylformylglycinamidine synthase 1 - Thermus thermophilus| (strain HB8 / ATCC 27634 / DSM 579) Length = 227 Score = 80.1 bits (196), Expect = 3e-14 Identities = 66/234 (28%), Positives = 103/234 (44%), Gaps = 2/234 (0%) Frame = +3 Query: 951 AIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDS 1130 AI+R G+N D + A AG I + + + L F G+ GGFSY D L Sbjct: 4 AIVRFPGANCDEDARFALEKAG-----IRAEFVWHTERDLRGFDGVFLPGGFSYGDYLR- 57 Query: 1131 AKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDM 1310 A ++ P+++ + F + +GVCNG Q++ G +PG + Sbjct: 58 ----AGALAAKSPVMEAVRRFAEE-GRYVVGVCNGFQILTEAGLLPGALLA--------- 103 Query: 1311 SQPRFTHNESGRFECRFISVAIGDSPSIMFKGM--EGSTLGIWSAHGEGRAFFPDGNVLS 1484 N + F C+ + V + + + F + G L + AHGEGR ++ D L+ Sbjct: 104 -------NLNLHFTCKEVGVRV-ERNDLPFTRLYPRGQVLRLPIAHGEGR-YYADPETLA 154 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + L RY + + +NPNGS IA + S G L +MPHPER+ Sbjct: 155 RLEGEGLVVFRYAP----LKDEADYNPNGSLHDIAGIVSEKGNVLGMMPHPERA 204
>Q72IH9:PURQ_THET2 Phosphoribosylformylglycinamidine synthase 1 - Thermus thermophilus| (strain HB27 / ATCC BAA-163 / DSM 7039) Length = 227 Score = 80.1 bits (196), Expect = 3e-14 Identities = 66/234 (28%), Positives = 103/234 (44%), Gaps = 2/234 (0%) Frame = +3 Query: 951 AIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDS 1130 AI+R G+N D + A AG I + + + L F G+ GGFSY D L Sbjct: 4 AIVRFPGANCDEDARFALEKAG-----IRAEFVWHTERDLRGFDGVFLPGGFSYGDYLR- 57 Query: 1131 AKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDM 1310 A ++ P+++ + F + +GVCNG Q++ G +PG + Sbjct: 58 ----AGALAAKSPVMEAVRRFAEE-GRYVVGVCNGFQILTEAGLLPGALLA--------- 103 Query: 1311 SQPRFTHNESGRFECRFISVAIGDSPSIMFKGM--EGSTLGIWSAHGEGRAFFPDGNVLS 1484 N + F C+ + V + + + F + G L + AHGEGR ++ D L+ Sbjct: 104 -------NLNLHFTCKEVGVRV-ERNDLPFTRLYPRGQVLRLPIAHGEGR-YYADPETLA 154 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + L RY + + +NPNGS IA + S G L +MPHPER+ Sbjct: 155 RLEGEGLVVFRYAP----LKDEADYNPNGSLHDIAGIVSEKGNVLGMMPHPERA 204
>Q5LS78:PURQ_SILPO Phosphoribosylformylglycinamidine synthase 1 - Silicibacter pomeroyi| Length = 222 Score = 80.1 bits (196), Expect = 3e-14 Identities = 68/236 (28%), Positives = 106/236 (44%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYADV 1121 + A++ GSN DR+++ AF AGF+ +S + ++ A L + I + GGFSY D Sbjct: 2 RAAVVVFPGSNCDRDLAVAFEQAGFD-----VSMVWHKDADLPQGIDIVGIPGGFSYGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P+ + R ++LGVCNG Q++ G +PG Sbjct: 57 LR-----CGAIAAQSPICKAVVAHTARGG-YALGVCNGFQVLTETGILPGA--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNV 1478 N ++ C+ + + + S S+ +G G +GI AH +G + D Sbjct: 102 -------LLRNAGLKYICKTVGLKVETSNSVFTEGYNAGDVIGIPIAHHDGNYYADD--- 151 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 LA L+ D + Y NPNG+ IA + S N R L +MPHPER+ Sbjct: 152 ------ETLAALKAED---RIAFTYTDNPNGARDDIAGILSANRRVLGMMPHPERA 198
>Q92AN8:PURQ_LISIN Phosphoribosylformylglycinamidine synthase 1 - Listeria innocua| Length = 227 Score = 80.1 bits (196), Expect = 3e-14 Identities = 70/237 (29%), Positives = 104/237 (43%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I+ GSN D +M A + E + + + SL F + GGFSY D L Sbjct: 2 KFAVIQFPGSNCDLDMLHAIRDSLGEEAEYVW----HAETSLAGFDAVLLPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + G A P + +F E +P LGVCNG Q++ +G +PG I Sbjct: 58 RT--GAIAKFSSIMPEVLRFAEM-GKP---VLGVCNGFQILTEIGLLPGALI-------- 103 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM--EGSTLGIWSAHGEGRAFFPDGNV 1478 N + F C+ + + + ++ + MF G+ EG + + AHGEG + D + Sbjct: 104 --------RNNNLHFICKTVPLRVANADT-MFTGLYEEGEIIQVPVAHGEGNYYCDDETL 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYP-FNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L D N + Y NPNGS IA + + G L +MPHPER+ Sbjct: 155 LK------------LKDNNQIVFTYDSVNPNGSRADIAGIVNERGNVLGMMPHPERA 199
>Q5FIV0:PURQ_LACAC Phosphoribosylformylglycinamidine synthase 1 - Lactobacillus| acidophilus Length = 223 Score = 79.0 bits (193), Expect = 7e-14 Identities = 66/235 (28%), Positives = 107/235 (45%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K+A++ GSN D +M AFH + + ++ SL F + GGFSY D L Sbjct: 2 KIAVVVFPGSNCDIDMYEAFHTVCKDDVEYVSY----KEKSLDGFDVVVLPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A RF+ I E + LGVCNG Q++ +G +PG Sbjct: 58 RTG----AIARFSN--IIPAVENMAKEGKLVLGVCNGFQILTEMGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 N+S +F C+ +++ + + + + + + I AHG+G +++ D NVL Sbjct: 102 ------LKKNDSLQFVCKTVTLEVENMHTPFTNEYADKEFIQIPIAHGDG-SYYADENVL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ ++ RY + NPNGS IA +C+ G L +MPHPER+ Sbjct: 155 EELEDNHQVVFRYHGE----------NPNGSLHDIAGICNKEGNVLGMMPHPERA 199
>Q9UX21:PURQ_SULSO Phosphoribosylformylglycinamidine synthase 1 - Sulfolobus| solfataricus Length = 224 Score = 78.6 bits (192), Expect = 9e-14 Identities = 62/233 (26%), Positives = 108/233 (46%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 +AII+ G+ + ++ A AG + D + + G+ GGFS+ D L Sbjct: 2 IAIIKFPGTTCETDVYKALIEAGVPTVIVKYKDFDPDR-----YNGVILPGGFSFGDYL- 55 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A AAS + + Q ++ +G+CNG Q++ G + G Sbjct: 56 RAGSIAASTETMKKVKQMAED-----GKIVIGICNGFQILVESGLLKGA----------- 99 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSD 1487 N RF +++ + + + +I+ KG++ + + AH EGR + D D Sbjct: 100 -----LLPNLKLRFISKWVYLKVIRADTILTKGLDKKIIRMPIAHAEGRYYVDD----ID 150 Query: 1488 VVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 K+++ L+YCD+ N++E NPNGS L IA++ + G + +MPHPER+ Sbjct: 151 YAKTHMV-LQYCDENGNISE--DVNPNGSLLNIASIANEEGNVIGMMPHPERA 200
>Q7VC88:PURQ_PROMA Phosphoribosylformylglycinamidine synthase 1 - Prochlorococcus| marinus Length = 218 Score = 78.2 bits (191), Expect = 1e-13 Identities = 67/234 (28%), Positives = 101/234 (43%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 + I+ GSN DR++ H A ++ L ++ L + GGFSY D L Sbjct: 3 IGIVVFPGSNCDRDV----HWATQGCLGMSTRFLWHESTDLNGLEAVVLPGGFSYGDYLR 58 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF P++ EF N+ LG+CNG Q++ LG +PG Sbjct: 59 CG----AIARF-APVLSSLLEFVNKGGKV-LGICNGFQILTELGLLPGA----------- 101 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGS-TLGIWSAHGEGRAFFPDGNVLS 1484 T N+ F C + + I + FK S + + AHGEGR Sbjct: 102 -----LTRNQELHFICDTVPLLISSQRTQWFKNYNQSKNIFLPIAHGEGR---------- 146 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + + L+ D +++ Y NPNGS IAA+ + +G L +MPHPER+ Sbjct: 147 --YQCSESILKKLQDEDSIALKYKNNPNGSINDIAAITNKSGNVLGMMPHPERA 198
>Q8Y6C0:PURQ_LISMO Phosphoribosylformylglycinamidine synthase 1 - Listeria monocytogenes| Length = 227 Score = 78.2 bits (191), Expect = 1e-13 Identities = 71/237 (29%), Positives = 106/237 (44%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I+ GSN D +M A + E + + + + SL F + GGFSY D L Sbjct: 2 KFAVIQFPGSNCDLDMLHAIRDSLGEEAEY----IWHAETSLAGFDAVLLPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + G A P + +F E +P LGVCNG Q++ +G +PG I Sbjct: 58 RT--GAIAKFSSIMPEVLRFAEM-GKP---VLGVCNGFQILTEIGLLPGALI-------- 103 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM--EGSTLGIWSAHGEGRAFFPDGNV 1478 N + F C+ + + + ++ S MF + EG + + AHGEG + D + Sbjct: 104 --------RNNNLHFICKTVPLRVANA-STMFTELYEEGEIIQVPVAHGEGNYYCDDETL 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYP-FNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L +K N N + Y NPNGS IA + + G L +MPHPER+ Sbjct: 155 LK--LKEN----------NQIVFTYDSVNPNGSRADIAGIVNERGNVLGMMPHPERA 199
>Q833Y8:PURQ_ENTFA Phosphoribosylformylglycinamidine synthase 1 - Enterococcus faecalis| (Streptococcus faecalis) Length = 224 Score = 77.8 bits (190), Expect = 2e-13 Identities = 64/234 (27%), Positives = 98/234 (41%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K+A+I GSN D ++ A E I + + SL +F G+ GGFSY D L Sbjct: 2 KLAVIVFPGSNCDADLLWAVK----EVMGIDAEFVRHDATSLAKFDGVLLPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A RF+ P+I + F G CNG Q++ +G +PG Sbjct: 58 RCG----AIARFS-PIINEVIRFATE-GKMVFGTCNGFQILTEIGLLPGT---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLS 1484 N+S RF C+ + + + + E ++ + AHGEG ++ D L Sbjct: 102 ------LLRNDSLRFICKSVPLKVNTHTKFTSEYPENVSIHLPVAHGEGN-YYCDEKTLK 154 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ + N + Y NGS IA +C+ G L +MPHPER+ Sbjct: 155 EL-----------KEKNQIVFTYQEKVNGSLANIAGICNEQGNVLGMMPHPERA 197
>Q8YU79:PURQ_ANASP Phosphoribosylformylglycinamidine synthase 1 - Anabaena sp. (strain| PCC 7120) Length = 224 Score = 77.4 bits (189), Expect = 2e-13 Identities = 64/235 (27%), Positives = 101/235 (42%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K ++ GSN DR+++ +P + +Q + + + GGFSY D L Sbjct: 2 KFGVVVFPGSNCDRDVAYVTRDLLGQPTRMVW----HQDTDIADLDVVIIPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A RF+ P++QQ E + + LG+CNG Q++ G +PG Sbjct: 58 RCG----AIARFS-PVMQQVVE-HAQKGKLVLGICNGFQVLTEAGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 N+ F C + + + + S+ + G + + AHGEGR F+ D L Sbjct: 102 ------LARNQDLHFICDRVPLTVESTNSLWTQAYNPGEVITLPIAHGEGR-FYADEATL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 S++ + RY + NPNGS IA +C G L +MPHPER+ Sbjct: 155 SEIEDNGQVLFRYAGE----------NPNGSLNNIAGICDRQGNVLGMMPHPERA 199
>Q6HPA5:PURQ_BACHK Phosphoribosylformylglycinamidine synthase 1 - Bacillus thuringiensis| subsp. konkukian Length = 227 Score = 77.0 bits (188), Expect = 3e-13 Identities = 68/237 (28%), Positives = 101/237 (42%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN D +M A E D D N L E+ I GGFSY D L Sbjct: 2 KFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTEN----LDEYDAILLPGGFSYGDYL 57 Query: 1125 --DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 + +A +++ Q +Q + LGVCNG Q++ G +PG Sbjct: 58 RCGAISRFANAMKAVQKAAEQGKPI--------LGVCNGFQILVESGLLPGA-------- 101 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 NE+ +F CR + + + ++ ++ E + I AHGEG ++ D Sbjct: 102 --------LMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGN-YYCDEE 152 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L + ++N RY + NPNGS IA + + G L +MPHPER+ Sbjct: 153 TLKQLEENNQIAFRYVE-----------NPNGSVSDIAGIVNEKGNVLGMMPHPERA 198
>Q73EN6:PURQ_BACC1 Phosphoribosylformylglycinamidine synthase 1 - Bacillus cereus| (strain ATCC 10987) Length = 227 Score = 77.0 bits (188), Expect = 3e-13 Identities = 68/237 (28%), Positives = 101/237 (42%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN D +M A E D D N L E+ I GGFSY D L Sbjct: 2 KFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTEN----LDEYDAILLPGGFSYGDYL 57 Query: 1125 --DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 + +A +++ Q +Q + LGVCNG Q++ G +PG Sbjct: 58 RCGAISRFANAMKAVQKAAEQGKPI--------LGVCNGFQILVESGLLPGA-------- 101 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 NE+ +F CR + + + ++ ++ E + I AHGEG ++ D Sbjct: 102 --------LMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGN-YYCDEE 152 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L + ++N RY + NPNGS IA + + G L +MPHPER+ Sbjct: 153 TLKQLEENNQIAFRYVE-----------NPNGSVSDIAGIVNEKGNVLGMMPHPERA 198
>Q81ZH3:PURQ_BACAN Phosphoribosylformylglycinamidine synthase 1 - Bacillus anthracis| Length = 227 Score = 77.0 bits (188), Expect = 3e-13 Identities = 68/237 (28%), Positives = 101/237 (42%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN D +M A E D D N L E+ I GGFSY D L Sbjct: 2 KFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTEN----LDEYDAILLPGGFSYGDYL 57 Query: 1125 --DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 + +A +++ Q +Q + LGVCNG Q++ G +PG Sbjct: 58 RCGAISRFANAMKAVQKAAEQGKPI--------LGVCNGFQILVESGLLPGA-------- 101 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 NE+ +F CR + + + ++ ++ E + I AHGEG ++ D Sbjct: 102 --------LMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGN-YYCDEE 152 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L + ++N RY + NPNGS IA + + G L +MPHPER+ Sbjct: 153 TLKQLEENNQIAFRYVE-----------NPNGSVSDIAGIVNEKGNVLGMMPHPERA 198
>Q3AS25:PURQ_CHLCH Phosphoribosylformylglycinamidine synthase 1 - Chlorobium| chlorochromatii (strain CaD3) Length = 234 Score = 76.6 bits (187), Expect = 3e-13 Identities = 72/235 (30%), Positives = 103/235 (43%), Gaps = 2/235 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHA-AGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 V ++ GSN D + + A + AG +P L + L + I GGFSY D L Sbjct: 6 VGVVVFPGSNCDHDTAYALASFAGVKP-----VMLWHNNHDLQGAQAIVLPGGFSYGDYL 60 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A RF+ PL+++ EF + LG+CNG Q++ G + G Sbjct: 61 RAG----AIARFS-PLMKEVVEFARKGYPV-LGICNGFQVLLESGLLEGA---------- 104 Query: 1305 DMSQPRFTHNESGRFECRFISVA-IGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 + N +F C ++ + S +G L I AHGEG F P VL Sbjct: 105 ------LSRNRDKKFLCCQTTITPVNCSTRFTEDYHQGEVLRIPIAHGEGNYFAPP-EVL 157 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + N +YC+ VT NPNGS L IA + + G L LMPHPER+ Sbjct: 158 ESLQEHNQIAFQYCNAQGEVT--VEANPNGSLLNIAGIVNRAGNVLGLMPHPERA 210
>Q63GT4:PURQ_BACCZ Phosphoribosylformylglycinamidine synthase 1 - Bacillus cereus| (strain ZK / E33L) Length = 227 Score = 76.6 bits (187), Expect = 3e-13 Identities = 68/237 (28%), Positives = 101/237 (42%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN D +M A E D D N L E+ I GGFSY D L Sbjct: 2 KFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTEN----LDEYDAILLPGGFSYGDYL 57 Query: 1125 --DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 + +A +++ Q +Q + LGVCNG Q++ G +PG Sbjct: 58 RCGAISRFANAMKAVQKAAEQGKPI--------LGVCNGFQILVESGLLPGA-------- 101 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 NE+ +F CR + + + ++ ++ E + I AHGEG ++ D Sbjct: 102 --------LMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGN-YYCDEE 152 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L + ++N RY + NPNGS IA + + G L +MPHPER+ Sbjct: 153 TLKKLEENNQIAFRYVE-----------NPNGSVSDIAGIVNEKGNVLGMMPHPERA 198
>Q3MG53:PURQ_ANAVT Phosphoribosylformylglycinamidine synthase 1 - Anabaena variabilis| (strain ATCC 29413 / PCC 7937) Length = 224 Score = 76.6 bits (187), Expect = 3e-13 Identities = 64/235 (27%), Positives = 100/235 (42%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K ++ GSN DR+++ +P + +Q + + + GGFSY D L Sbjct: 2 KFGVVVFPGSNCDRDVAYVTRDLLGQPTRMVW----HQDTDIADLDVVIIPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A RF+ P++QQ E + + LG+CNG Q++ G +PG Sbjct: 58 RCG----AIARFS-PVMQQVVE-HAQKGKLVLGICNGFQVLTEAGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 N F C + + + + S+ + G + + AHGEGR F+ D L Sbjct: 102 ------LARNRDLHFICDRVPLTVESTNSLWTQAYNPGEVITLPIAHGEGR-FYADEATL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 S++ + RY + NPNGS IA +C G L +MPHPER+ Sbjct: 155 SEIEDNGQVLFRYAGE----------NPNGSLNNIAGICDRQGNVLGMMPHPERA 199
>Q3AII4:PURQ_SYNSC Phosphoribosylformylglycinamidine synthase 1 - Synechococcus sp.| (strain CC9605) Length = 216 Score = 76.3 bits (186), Expect = 5e-13 Identities = 65/233 (27%), Positives = 97/233 (41%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 + +I GSN DR++ A ++ + +++ L+ F I GGFSY D L Sbjct: 3 IGVIVFPGSNCDRDVQWATDGC----LGMSTRRVWHEETDLSGFDAIILPGGFSYGDYLR 58 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF P +Q +F + LG+CNG Q++ LG +PG Sbjct: 59 CG----AIARF-APALQSLIDFAAKGGRV-LGICNGFQVLTELGLLPGA----------- 101 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSD 1487 T N++ F C + + + +G L + AHGEGR D Sbjct: 102 -----LTRNQNLHFICEDAPLKVVSQRTAWMQGYNDRALTLPIAHGEGRYQCSDDT---- 152 Query: 1488 VVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L+ D + + Y NPNGS IA + + +G L LMPHPER+ Sbjct: 153 --------LKQLQDDDAIALSYGNNPNGSVFNIAGITNASGSVLGLMPHPERA 197
>Q81IQ4:PURQ_BACCR Phosphoribosylformylglycinamidine synthase 1 - Bacillus cereus| (strain ATCC 14579 / DSM 31) Length = 227 Score = 76.3 bits (186), Expect = 5e-13 Identities = 68/237 (28%), Positives = 101/237 (42%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN D +M A E D D N L E+ I GGFSY D L Sbjct: 2 KFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTEN----LDEYDAILLPGGFSYGDYL 57 Query: 1125 --DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 + +A +++ Q +Q + LGVCNG Q++ G +PG I Sbjct: 58 RCGAISRFANAMKAVQKAAEQGKPI--------LGVCNGFQILVESGLLPGALI------ 103 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 NE+ +F CR + + + ++ ++ E + I AHGEG + + Sbjct: 104 ----------RNENLKFMCRTVQLRVENNETMFTSQYEKDEIINIPIAHGEGNYYCDE-- 151 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 A L+ ++ N + Y NPNGS IA + + G L +MPHPER+ Sbjct: 152 ----------ATLKQLEENNQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERA 198
>Q4L577:PURQ_STAHJ Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus| haemolyticus (strain JCSC1435) Length = 223 Score = 75.5 bits (184), Expect = 8e-13 Identities = 71/237 (29%), Positives = 109/237 (45%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLN-QKASLTEFRGIAFVGGFSYADV 1121 K A++ GSN DR+M A +G + +D ++ ++ SL + G+ GGFS+ D Sbjct: 2 KFAVLVFPGSNCDRDMYNAAIKSGAQ------ADYVDYRETSLDGYDGVLIPGGFSFGDY 55 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L S G AS+ P+I + + N LGVCNG Q++ +G +PG Sbjct: 56 LRS--GAMASVA---PIINEVKRLANDGKPV-LGVCNGFQILTEIGLLPGA--------- 100 Query: 1302 GDMSQPRFTHNESGRFECRF--ISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGN 1475 HN+S F R + +A +P G E + AHGEG + D + Sbjct: 101 -------LLHNDSHLFISRNENLKIANNQTPFTNLYG-ENEIVVYPVAHGEGHYYCTD-D 151 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + +++V++N L Y D NPNGS IA + + G +MPHPER+ Sbjct: 152 IYNELVENNQIILTYED-----------NPNGSHENIAGIVNKAGNVCGMMPHPERA 197
>Q2NF29:PURQ_METST Phosphoribosylformylglycinamidine synthase 1 - Methanosphaera| stadtmanae (strain DSM 3091) Length = 221 Score = 75.5 bits (184), Expect = 8e-13 Identities = 65/234 (27%), Positives = 103/234 (44%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 V IIR G+N DR++ A + G I ++ L++ + GGFSY D L Sbjct: 9 VGIIRFPGTNCDRDIEYAVNLVGANSHYIYWNE-----TDLSQMDVVIIPGGFSYGDYLR 63 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A SI P+I ++F + + LG+CNG Q++ + VPG Sbjct: 64 -----AGSIAGITPIIDAIKDFAKKENPV-LGICNGAQILGEIDLVPGV----------- 106 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFK-GMEGSTLGIWSAHGEGRAFFPDGNVLS 1484 F NE+ +F C+ + + + + K + + + AH EGR + + L Sbjct: 107 -----FIENENAKFICKSKKLKVNTTRTPFTKLYKKNEVIDLPIAHKEGRYYTDNLETLY 161 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 D +N L + D NPNGS I +C+ +G +A+MPHPER+ Sbjct: 162 D---NNQIVLTFEDG----------NPNGSLDNITGVCNVDGNVVAVMPHPERA 202
>Q3AYR1:PURQ_SYNS9 Phosphoribosylformylglycinamidine synthase 1 - Synechococcus sp.| (strain CC9902) Length = 217 Score = 75.1 bits (183), Expect = 1e-12 Identities = 63/234 (26%), Positives = 102/234 (43%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 + ++ GSN DR++ A ++ L +++ L+ + GGFSY D L Sbjct: 3 IGVVVFPGSNCDRDVQWATEGC----LNLPTRRLWHEETDLSGLDAVVLPGGFSYGDYLR 58 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF P++Q +F ++ LG+CNG Q++ LG +PG Sbjct: 59 CG----AIARF-APVLQSLMDFASKGGRV-LGICNGFQVLTELGLLPGA----------- 101 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNVLS 1484 T N++ F C + + + + K ++L + AHGEGR Sbjct: 102 -----LTRNQNLHFICEDAPLHVSSTRTDWLKAYGNAASLVLPIAHGEGR---------- 146 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + L+ D + + Y NPNGS IA + +P+G L LMPHPER+ Sbjct: 147 --YQCSNDTLKQLQDQDCIALRYGSNPNGSVDDIAGITNPSGNVLGLMPHPERA 198
>Q3B397:PURQ_PELLD Phosphoribosylformylglycinamidine synthase 1 - Pelodictyon luteolum| (strain DSM 273) (Chlorobium luteolum (strain DSM 273)) Length = 231 Score = 75.1 bits (183), Expect = 1e-12 Identities = 72/235 (30%), Positives = 103/235 (43%), Gaps = 2/235 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 + ++ GSN D + A A FE M L + L + I GGFSY D L Sbjct: 6 IGVVVFPGSNCDHDTMHA--VASFEGVKPVM--LWHGSHDLQGAKAIILPGGFSYGDYLR 61 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A SI P++Q+ + + LG+CNG Q++ G + G Sbjct: 62 -----AGSIARFSPIMQEVVDAAGKGLPV-LGICNGFQVLLESGLLDGA----------- 104 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM--EGSTLGIWSAHGEGRAFFPDGNVL 1481 + N +F CR + +S + MF G+ E L I AHGEG F P V+ Sbjct: 105 -----LSRNRDKKFLCRDTYIRPVNS-NTMFTGLYREDEVLSIPIAHGEGNYFAPP-EVI 157 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + + RY D +V++ NPNGS IA + + NG L LMPHPER+ Sbjct: 158 ESLEEHDQVVFRYTDREGHVSD--EANPNGSVGNIAGIMNRNGNVLGLMPHPERA 210
>Q167J3:PURQ_ROSDO Phosphoribosylformylglycinamidine synthase 1 - Roseobacter| denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) Length = 222 Score = 74.7 bits (182), Expect = 1e-12 Identities = 62/234 (26%), Positives = 97/234 (41%), Gaps = 2/234 (0%) Frame = +3 Query: 951 AIIREEGSNSDREMSAAFHAAGFEPWDITMSDL-LNQKASLTEFRGIAFVGGFSYADVLD 1127 A++ GSN DR+++ AF AAG + + D L + + I GGFS+ D L Sbjct: 4 AVVVFPGSNCDRDLAVAFEAAGAQVTKVWHKDTDLPEGVDI-----IGIPGGFSFGDYLR 58 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 +I N P+ + R + +G+CNG Q++ G +PG Sbjct: 59 -----CGAIAANSPICRSVAAHAERGG-YVIGICNGFQVLTETGLLPGA----------- 101 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVLS 1484 N ++ C+ +++ + S S +G G T+ I AH +G F D + Sbjct: 102 -----LLRNAGLKYICKTVALKVETSASAFTEGYTAGDTISIPIAHHDGNYFADDETIAR 156 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + V Y PNG+ IA + S N R L +MPHPER+ Sbjct: 157 ------------LQGEDRVAFTYEDTPNGAKADIAGILSSNRRVLGMMPHPERA 198
>Q8TPF0:PURQ_METAC Phosphoribosylformylglycinamidine synthase 1 - Methanosarcina| acetivorans Length = 232 Score = 74.7 bits (182), Expect = 1e-12 Identities = 63/236 (26%), Positives = 108/236 (45%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K+AII+ G+N D ++ + + + ++ +LT F G+ GGFSY D L Sbjct: 2 KIAIIQFGGTNCDMDVLHVLK----DVVGVDAETVWYKEENLTGFDGVVVPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I P++ ++ LG+CNG Q++ + G Sbjct: 58 R-----AGAIAARTPIMDSVKKIAAEGKPV-LGICNGFQVLTEARLLAGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAI--GDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNV 1478 T NE +F C + ++ + D+P K +G + + AH EG+ F+ + + Sbjct: 102 ------LTTNEYPKFRCHWTNLRVETADTP-FTSKFRKGEVIRMPIAHMEGK-FYAEEST 153 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L+++ ++ RY D+ VT+ NPNGS IA + + + L LMPHPER+ Sbjct: 154 LAELDENEQVVFRYVDEKGRVTD--EANPNGSLENIAGILNASRNILGLMPHPERA 207
>Q55843:PURQ_SYNY3 Phosphoribosylformylglycinamidine synthase 1 - Synechocystis sp.| (strain PCC 6803) Length = 224 Score = 74.3 bits (181), Expect = 2e-12 Identities = 71/234 (30%), Positives = 104/234 (44%), Gaps = 3/234 (1%) Frame = +3 Query: 954 IIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSA 1133 II GSN DR+++ AG D + +Q+ L + GGFSY D L Sbjct: 6 IIVFPGSNCDRDIATV--TAGL--LDQPTRFIWHQETDLHGVDVVVLPGGFSYGDYLRCG 61 Query: 1134 KGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDMS 1313 A RF+ P++ + N LG+CNG Q++ +G +PG I Sbjct: 62 ----AIARFS-PIMTAIIDHANAGKRV-LGICNGFQVLTEVGLLPGALI----------- 104 Query: 1314 QPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGS---TLGIWSAHGEGRAFFPDGNVLS 1484 N F C ++V + + ++ KG + TL I AHGEGR +F DG+ L Sbjct: 105 -----RNRDLHFICDRVTVRVESNQTVWTKGYQSQQVITLPI--AHGEGR-YFADGDTLK 156 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + RY + +T NPNGS IA + + G L +MPHPER+ Sbjct: 157 ALEDNEQILFRYSNAQGELTT--DSNPNGSLHNIAGITNVQGNVLGMMPHPERA 208
>Q8PTB0:PURQ_METMA Phosphoribosylformylglycinamidine synthase 1 - Methanosarcina mazei| (Methanosarcina frisia) Length = 232 Score = 74.3 bits (181), Expect = 2e-12 Identities = 61/235 (25%), Positives = 107/235 (45%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K+AII+ G+N D ++ + + + ++ SLT F G+ GGFSY D L Sbjct: 2 KIAIIQFGGTNCDMDVLHVLK----DVVGVDAETVWYKEESLTGFDGVVVPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I P++ ++ + LG+CNG Q++ + G Sbjct: 58 R-----AGAIAARTPIMDSIKKIASEGKPV-LGICNGFQILTEARLLEGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 T NE +F C + ++ + + + K +G + + AH EG+ F+ + L Sbjct: 102 ------LTTNEYPKFRCHWTNLRVETANTPFTSKFRKGEVIKLPIAHMEGK-FYAEEATL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +++ ++ RY D+ +T+ NPNGS IA + + + L LMPHPER+ Sbjct: 155 AELDENEQVVFRYVDEKGRLTD--KANPNGSLENIAGIVNSSRNVLGLMPHPERA 207
>P12041:PURQ_BACSU Phosphoribosylformylglycinamidine synthase 1 - Bacillus subtilis| Length = 227 Score = 74.3 bits (181), Expect = 2e-12 Identities = 70/235 (29%), Positives = 103/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN D +M +HA E + + +++ SL F G+ GGFSY D L Sbjct: 2 KFAVIVLPGSNCDIDM---YHAVKDELGH-EVEYVWHEETSLDGFDGVLIPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 G A P ++Q +P LGVCNG Q++ LG +PG Sbjct: 58 RC--GAIARFANIMPAVKQAAA-EGKP---VLGVCNGFQILQELGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 N+ +F CR + + + + ++ E G ++ I AHGEG + D Sbjct: 102 ------MRRNKDLKFICRPVELIVQNDETLFTASYEKGESITIPVAHGEGNFYCDD---- 151 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 LA L+ + N + Y N NGS IA + + G L +MPHPER+ Sbjct: 152 -----ETLATLK---ENNQIAFTYGSNINGSVSDIAGVVNEKGNVLGMMPHPERA 198
>Q65MS9:PURQ_BACLD Phosphoribosylformylglycinamidine synthase 1 - Bacillus licheniformis| (strain DSM 13 / ATCC 14580) Length = 227 Score = 74.3 bits (181), Expect = 2e-12 Identities = 69/235 (29%), Positives = 105/235 (44%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN D +M FHA E + + + + SL E+ G+ GGFSY D L Sbjct: 2 KFAVIVLPGSNCDIDM---FHAIKDELGE-EAEYVWHTETSLDEYDGVLIPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 G A P +++ E +P LGVCNG Q++ LG +PG Sbjct: 58 RC--GAIARFANIMPAVKKAAE-EGKP---VLGVCNGFQILQELGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNVL 1481 N+ +F CR + + + ++ ++ +G ++ I AHGEG F+ D L Sbjct: 102 ------MRRNKDLKFICRPVELIVQNNETLFTSSYGKGESITIPVAHGEGN-FYCDEETL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + ++N Y D N GS IA + + G L +MPHPER+ Sbjct: 155 AGLQENNQIAFTYGTDIN-----------GSVADIAGVVNEKGNVLGMMPHPERA 198
>Q1AXB7:PURQ_RUBXD Phosphoribosylformylglycinamidine synthase 1 - Rubrobacter| xylanophilus (strain DSM 9941 / NBRC 16129) Length = 220 Score = 73.9 bits (180), Expect = 2e-12 Identities = 72/236 (30%), Positives = 96/236 (40%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 +V ++ GSN DR+ A AG EP ++ +D A L + GGFSY D L Sbjct: 2 RVGVVVFPGSNCDRDALHAVERAGAEPVELWHAD-----ADLKGSDAVILPGGFSYGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A R PL E + R LGVCNG Q++ +PG Sbjct: 57 RPG-AIARFARVMGPL-----EAFAREGGPVLGVCNGFQVLCEAHLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAI--GDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNV 1478 N RF CR + V + D+P G L + AH EG +F D Sbjct: 101 ------LLQNRGLRFVCRRVRVRVERADTPWTAACA-PGEELTLPVAHNEGN-YFADPAT 152 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L+ + + LRY + NPNGS IA +CS + LMPHPER+ Sbjct: 153 LARLEEEGRVVLRYLE-----------NPNGSANDIAGVCSEGRNVVGLMPHPERA 197
>Q3J4K2:PURQ_RHOS4 Phosphoribosylformylglycinamidine synthase 1 - Rhodobacter| sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) Length = 222 Score = 73.9 bits (180), Expect = 2e-12 Identities = 73/239 (30%), Positives = 102/239 (42%), Gaps = 5/239 (2%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYADV 1121 K A+I GSN DR+++ AF AG + ++ + ++ +L E + V GGFS+ D Sbjct: 2 KAAVITFPGSNCDRDLATAFEKAGAD-----VTRVWHKDTALPEGVDVVGVPGGFSFGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P+ R + LG+CNG Q++ G +PG Sbjct: 57 LR-----CGAIAARSPIAAAMIRHAERGG-YVLGICNGFQVLTETGLLPGA--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFP----D 1469 N +F CR + + + + S G W+A R FP D Sbjct: 102 -------LMRNAGLKFICRRVDLRVATADSAFTSG--------WAAGDAVR--FPIAHHD 144 Query: 1470 GNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 GN +D LA LR D V Y NPNGS IA + S N R L LMPHPER+ Sbjct: 145 GNYTAD--PETLARLRGED---RVAFTYLDNPNGSMEDIAGILSANRRVLGLMPHPERA 198
>Q46LE9:PURQ_PROMT Phosphoribosylformylglycinamidine synthase 1 - Prochlorococcus| marinus (strain NATL2A) Length = 217 Score = 73.9 bits (180), Expect = 2e-12 Identities = 68/234 (29%), Positives = 100/234 (42%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 + II GSN DR++ A + S L ++ L F I GGFSY D L Sbjct: 3 IGIIVFPGSNCDRDVRWATEGC----LGVPTSFLWHETTDLDGFDAIVIPGGFSYGDYLR 58 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF P++ F ++ LG+CNG Q++ LG + G Sbjct: 59 CG----AIARF-APVLNSLISFVDKGGKV-LGICNGFQILTELGLLQGA----------- 101 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEG-STLGIWSAHGEGRAFFPDGNVLS 1484 T N++ F C +++I + S K + ++ + AHGEGR + +VL Sbjct: 102 -----LTRNKNLHFICDRANLSIESTKSTWMKNYKKHDSISLPIAHGEGR-YQCSSDVLK 155 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + LRY D NPNGS IA + + G L +MPHPER+ Sbjct: 156 KLQDDDSVALRYAD-----------NPNGSIHDIAGITNKKGNVLGMMPHPERA 198
>Q4FLJ5:PURQ_PELUB Phosphoribosylformylglycinamidine synthase 1 - Pelagibacter ubique| Length = 227 Score = 73.9 bits (180), Expect = 2e-12 Identities = 63/231 (27%), Positives = 96/231 (41%) Frame = +3 Query: 951 AIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDS 1130 ++I GSN DR+M A GF+ + D+ K+ L + GGFSY D L Sbjct: 4 SVITFPGSNCDRDMDVALKKFGFKNKMVWHDDVELPKSDL-----VVLPGGFSYGDYLR- 57 Query: 1131 AKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDM 1310 S+ +++ F +GVCNG Q++ G +PG Sbjct: 58 ----CGSMASKSKIMKSVLNFAQGGGKV-MGVCNGFQILVESGLLPGV------------ 100 Query: 1311 SQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLSDV 1490 N+ F C+ + V + + FK + + AH EG +F + + ++ Sbjct: 101 ----LLRNKYLEFICKNVFVKANNKDNSYFKDDKKNIYEFHIAHNEGN-YFCSNDQIKEI 155 Query: 1491 VKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPER 1643 +N L Y D+ NV E NPNGS IA + + L +MPHPER Sbjct: 156 NDNNQIALFYSDENGNVNE--QSNPNGSLQNIAGVFNKQKNVLGMMPHPER 204
>Q6G336:PURQ_BARHE Phosphoribosylformylglycinamidine synthase 1 - Bartonella henselae| (Rochalimaea henselae) Length = 223 Score = 73.6 bits (179), Expect = 3e-12 Identities = 66/234 (28%), Positives = 102/234 (43%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFH-AAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 K AII+ G N DR+M AA H G EP I ++ +++ + I GGFSY D Sbjct: 2 KTAIIQLPGLNRDRDMVAALHHITGVEPLKIWQTE-----STIPDVDVIVIPGGFSYGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P++Q +E + T +G+CNG Q++ G +PG Sbjct: 57 LR-----CGAIGARTPVLQAVREKAQKGVTV-IGICNGFQILLEAGLLPGT--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNV 1478 N S +F CR I + + + + + +G + AH +G +F D Sbjct: 102 -------LMRNTSLKFVCREIKLEVVNVNTKFSRYYSKGQIICCPVAHHDGN-YFVDSET 153 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L + ++ RY ++ N PNGS IA + + G L +MPHPE Sbjct: 154 LKQMEENEQIIFRYAENTN---------PNGSVNDIAGIINKAGNILGMMPHPE 198
>Q2JPK0:PURQ_SYNJB Phosphoribosylformylglycinamidine synthase 1 - Synechococcus sp.| (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium Yellowstone B-Prime) Length = 225 Score = 72.8 bits (177), Expect = 5e-12 Identities = 66/227 (29%), Positives = 96/227 (42%), Gaps = 1/227 (0%) Frame = +3 Query: 969 GSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDSAKGWAA 1148 GSN DR+++ P + + +++ L+E + GGFSY D L A Sbjct: 13 GSNCDRDVAWVTRGLLGCPTRL----IWHRETDLSELDVVVLPGGFSYGDYLRCG----A 64 Query: 1149 SIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDMSQPRFT 1328 RF P++ +E R + LG+CNG Q++ G +PG Sbjct: 65 IARF-APVMGSLKEHAARGG-YVLGICNGFQILTEAGLLPGA----------------LV 106 Query: 1329 HNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNL 1505 N + F C + + + +GSTL + AHGEGR + D + L + Sbjct: 107 RNANLHFICDRVGIRVERQDLPWTSAYPQGSTLTLPIAHGEGR-YTCDPDTLKQLQDRGQ 165 Query: 1506 APLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 RY P PNGS IA +C P+GR L LMPHPER+ Sbjct: 166 IVFRYA----------PVAPNGSVDNIAGICDPSGRILGLMPHPERA 202
>Q1WU60:PURQ_LACS1 Phosphoribosylformylglycinamidine synthase 1 - Lactobacillus| salivarius subsp. salivarius (strain UCC118) Length = 224 Score = 72.8 bits (177), Expect = 5e-12 Identities = 62/239 (25%), Positives = 106/239 (44%), Gaps = 2/239 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K+A+I GSN D ++ A H D + + ++ +L F + GGFSY D L Sbjct: 2 KIAVIVFPGSNCDIDLYEALHTV----CDADVEYVSYKQDNLDGFDAVMLPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A RF+ P++ EF G CNG Q++ +G +PG Sbjct: 58 RCG----AIARFS-PIMPAVIEFAKNGKPV-FGTCNGFQILTEVGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM--EGSTLGIWSAHGEGRAFFPDGNV 1478 N S +F C+ + + + ++ + F + +G + + AH +G +++ D + Sbjct: 102 ------LKQNNSLKFVCKTVELTV-ENTNTPFTSLYKKGEKINLPIAHADG-SYYADEEL 153 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSFMM 1655 L+++ ++ RY + NPNGS IA + + G L +MPHPER+ M Sbjct: 154 LAELEENGQVVFRYSKE----------NPNGSLNDIAGITNKQGNVLGMMPHPERAVEM 202
>Q1G9F7:PURQ_LACDA Phosphoribosylformylglycinamidine synthase 1 - Lactobacillus| delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081) Length = 224 Score = 72.8 bits (177), Expect = 5e-12 Identities = 61/235 (25%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I+ GSN D ++ A H ++ + ++++SL F + GGFSY D L Sbjct: 2 KFAVIQFPGSNCDIDLYEALHTV----CGADVAYVPSKESSLDGFDAVMLPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + G A P I + + +P G CNG Q++ G +PG Sbjct: 58 RA--GAIARFTNIMPAIVEMAKA-GKP---VFGTCNGFQILTEAGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 N+S +F C+ + + + ++ +I + G + + AH +G +F+ D L Sbjct: 102 ------LKRNDSLKFVCKTVELEVANNDTIFTSEYQKGEKINLPIAHADG-SFYADPETL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + RY + NPNGS IA + + G L +MPHPER+ Sbjct: 155 QKIEDNGQVVFRYSKE----------NPNGSLNNIAGITNERGNVLGMMPHPERA 199
>Q5L3D3:PURQ_GEOKA Phosphoribosylformylglycinamidine synthase 1 - Geobacillus| kaustophilus Length = 228 Score = 72.8 bits (177), Expect = 5e-12 Identities = 67/237 (28%), Positives = 107/237 (45%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN D +M +HA E + + + + + +L F + GGFSY D L Sbjct: 2 KFAVVVFPGSNCDVDM---YHAIADELGE-EVEYVWHDEDNLDRFDAVLLPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPL--IQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 S A RF++ + +++ E +P LGVCNG Q++ G +PG Sbjct: 58 RSG----AIARFSKVMAAVKKAAEA-GKP---VLGVCNGFQILLEAGLLPGA-------- 101 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 N+ +F CR + + + + ++ E G + I AHGEG ++ D Sbjct: 102 --------MRRNQGLKFICRPVQLTVENHETMFTSAYEKGEVITIPIAHGEGN-YYCDEQ 152 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L +V++ RY + NPNGS IA + + G L +MPHPER+ Sbjct: 153 TLERLVENRQIVFRYHGE----------NPNGSLADIAGIVNEQGNVLGMMPHPERA 199
>Q4JXF1:PURQ_CORJK Phosphoribosylformylglycinamidine synthase 1 - Corynebacterium| jeikeium (strain K411) Length = 223 Score = 72.8 bits (177), Expect = 5e-12 Identities = 66/235 (28%), Positives = 97/235 (41%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++ +I G+ D + A AG EP ++ +D L + GGFSY D L Sbjct: 4 RIGVITFPGTLDDVDAVRAVRLAGAEPVELWHAD-----EDLKNVDAVVVPGGFSYGDYL 58 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I P ++ R T LG+CNG Q++ G +PG Sbjct: 59 R-----AGAIAAIAPAMKSVVAAAER-GTPVLGICNGFQILQEAGLLPGA---------- 102 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNVL 1481 T NE F CR I + + ++ + EG+ + + S HGEGR Sbjct: 103 ------LTRNEGLHFVCRDIYLDVENTSTAWTNQFAEGTKILVPSKHGEGR--------- 147 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +++ L + V Y N NGS IA +CS NGR + LMPHPE + Sbjct: 148 ---FQASEETLERLEGEGRVVFRYVENHNGSRNSIAGVCSENGRVVGLMPHPEHA 199
>Q30TB2:PURQ_THIDN Phosphoribosylformylglycinamidine synthase 1 - Thiomicrospira| denitrificans (strain ATCC 33889 / DSM 1351) Length = 224 Score = 72.0 bits (175), Expect = 9e-12 Identities = 66/238 (27%), Positives = 106/238 (44%), Gaps = 4/238 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEP---WDITMSDLLNQKASLTEFRGIAFVGGFSYA 1115 KV I++ G+N + + AF + G E W SD + L + GGFSY Sbjct: 2 KVTILQFPGTNCEYDAQHAFKSLGAETEILWH--KSDTIPSDTDL-----LIVAGGFSYG 54 Query: 1116 DVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLG 1295 D L S A +F+ P+++ ++ + LG+CNG Q++ G +PG Sbjct: 55 DYLRSG----AIAKFS-PVMKAVIKYADDGGKV-LGICNGFQVLTESGLLPGA------- 101 Query: 1296 AGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDG 1472 NES F + + + ++ +I + ++ G + I AH +G + D Sbjct: 102 ---------LKRNESLHFLSKHHHLKVINNENIFLEKLDKGDIVNIPIAHHDGNYYIDDS 152 Query: 1473 NVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L ++ +N L+YCD+ N NPNGS IA +C+ LMPHPER+ Sbjct: 153 G-LKELYANNQVLLKYCDENGNDK-----NPNGSIDSIAGICNKERNVFGLMPHPERA 204
>P99166:PURQ_STAAN Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus aureus| (strain N315) Length = 223 Score = 72.0 bits (175), Expect = 9e-12 Identities = 69/235 (29%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G E + ++ SL+ F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDY-----RETSLSGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I + + LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PIISEVKRLATEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS-AHGEGRAFFPDGNVL 1481 HN+S F R + I ++ + E I+ AHGEG + D + Sbjct: 101 ------LLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDE--I 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +K+N N + Y NPNGS IA + + G +MPHPER+ Sbjct: 153 YQQLKAN----------NQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERA 197
>P65904:PURQ_STAAM Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus aureus| (strain Mu50 / ATCC 700699) Length = 223 Score = 72.0 bits (175), Expect = 9e-12 Identities = 69/235 (29%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G E + ++ SL+ F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDY-----RETSLSGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I + + LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PIISEVKRLATEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS-AHGEGRAFFPDGNVL 1481 HN+S F R + I ++ + E I+ AHGEG + D + Sbjct: 101 ------LLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDE--I 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +K+N N + Y NPNGS IA + + G +MPHPER+ Sbjct: 153 YQQLKAN----------NQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERA 197
>Q2G9J6:PURQ_NOVAD Phosphoribosylformylglycinamidine synthase 1 - Novosphingobium| aromaticivorans (strain DSM 12444) Length = 225 Score = 72.0 bits (175), Expect = 9e-12 Identities = 69/233 (29%), Positives = 97/233 (41%), Gaps = 2/233 (0%) Frame = +3 Query: 951 AIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTE-FRGIAFVGGFSYADVLD 1127 A+I GSN DR+M+ A + T+ + + A L E IA GGFSY D L Sbjct: 6 AVITFPGSNCDRDMAVAIE----QVCGGTVHRVWHGDADLPEGLDFIALPGGFSYGDYLR 61 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 S A S P++Q R T LGVCNG Q++ G +PG Sbjct: 62 SGAMAARS-----PVMQAVVRAAERGVTV-LGVCNGFQVLTEAGLLPGA----------- 104 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVLS 1484 N RF CR + + + ++ S+ G + G + I AH +G +F D L Sbjct: 105 -----LMRNAGIRFVCRDVKLTVENNQSLFTAGYDAGQQITIPVAHHDGN-YFADDATLD 158 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPER 1643 + RY ++ N GS IA + + G L +MPHPER Sbjct: 159 RIEGEGRVAFRYAEEVN-----------GSARNIAGVLNDRGNVLGMMPHPER 200
>Q2RGU4:PURQ_MOOTA Phosphoribosylformylglycinamidine synthase 1 - Moorella thermoacetica| (strain ATCC 39073) Length = 236 Score = 72.0 bits (175), Expect = 9e-12 Identities = 65/234 (27%), Positives = 102/234 (43%), Gaps = 1/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K +I GSN D+++ A + + D L + S++ + + GGFSY D L Sbjct: 2 KFGVIVFPGSNCDQDVHYALGSVLGQNVDY----LWHGDTSVSGYDCLILPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A RF P++ +F R LG+CNG Q++ G +PG Sbjct: 58 RAG----AIARF-APIMPAVIDFA-RSGGLVLGICNGFQILLEAGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 N +F C++ + + ++ + + EG + I AHGEG ++ D L Sbjct: 102 ------MMRNACLQFRCQWTCLKVDNNATPFTNRFREGQVVRIPIAHGEGN-YYADAATL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPER 1643 + + + RYC VT NPNGS IA + + G L +MPHPER Sbjct: 155 AQLEANRQIIFRYCSPDGEVTPAA--NPNGSVGNIAGIINREGNVLGMMPHPER 206
>Q3AD64:PURL_CARHZ Phosphoribosylformylglycinamidine synthase 2 - Carboxydothermus| hydrogenoformans (strain Z-2901 / DSM 6008) Length = 728 Score = 72.0 bits (175), Expect = 9e-12 Identities = 44/124 (35%), Positives = 76/124 (61%), Gaps = 3/124 (2%) Frame = +3 Query: 429 KKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLL--QTLF 602 +++ E++ L + LI++ HD+SDGGL V++ E AFAG GVN++ LL + LF Sbjct: 600 RRIIELLPLLKKQGLINSAHDVSDGGLAVSLCEAAFAGELGVNIDF---TTSLLPQEFLF 656 Query: 603 AEELGLVI-EVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDLR 779 +E++GLVI V + + + + AGV +G V EIE+ ++G+ ++E+ S+L+ Sbjct: 657 SEKVGLVIVSVSPEKEEEFIKSVKNAGVFVLKLGRVNGKDEIEICLNGQRVIQEKLSELK 716 Query: 780 DLWE 791 L+E Sbjct: 717 ALYE 720 Score = 38.5 bits (88), Expect = 0.11 Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 11/142 (7%) Frame = +3 Query: 354 GCSALAQAFDQIGNDCPDIEDV--PYLKKVF-EVVQELLSERLISAGHDISDGGLIVTIL 524 G + ++ Q G D V P+++K+ E E L I D+ GL + Sbjct: 211 GATFASEELSQDGEDKRPSVQVGDPFMEKLLLEACLEALEYGHIVGMQDLGAAGLTSSSS 270 Query: 525 EMAFAGNCGVNLNIE--------LKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAG 680 EMA G G+ L ++ + +++ + E + LV+E +D +++K Sbjct: 271 EMAARGKSGIRLYLDRVPLREEGMTPYEIMLSESQERMLLVVEKGYED-EIIKI-FKKWD 328 Query: 681 VSANVIGEVTAAPEIELLVDGE 746 ++A V+GE+T EIE+ DGE Sbjct: 329 LNAVVVGEITDGEEIEVFFDGE 350
>Q8CPP0:PURQ_STAES Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus| epidermidis (strain ATCC 12228) Length = 223 Score = 71.6 bits (174), Expect = 1e-11 Identities = 66/235 (28%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G + + ++ +L F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMYNAAIKSGVDAAYVDY-----RETTLDGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I++ + F LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PIIKEVKRFAKEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 HN+S F R ++ I ++ + ++ + AHGEG + D Sbjct: 101 ------LLHNDSHLFISRNETLKITNNQTPFTHLYVKNENVVYPVAHGEGHYYCTD---- 150 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 R +D N + Y NPNGS IA + + G +MPHPER+ Sbjct: 151 --------EIYRELNDNNQIILKYTNNPNGSYEDIAGIVNKEGNVCGMMPHPERA 197
>Q5HQA2:PURQ_STAEQ Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus| epidermidis (strain ATCC 35984 / RP62A) Length = 223 Score = 71.6 bits (174), Expect = 1e-11 Identities = 66/235 (28%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G + + ++ +L F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMYNAAIKSGVDAAYVDY-----RETTLDGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I++ + F LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PIIKEVKRFAKEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 HN+S F R ++ I ++ + ++ + AHGEG + D Sbjct: 101 ------LLHNDSHLFISRNETLKITNNQTPFTHLYVKNENVVYPVAHGEGHYYCTD---- 150 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 R +D N + Y NPNGS IA + + G +MPHPER+ Sbjct: 151 --------EIYRELNDNNQIILKYTNNPNGSYEDIAGIVNKEGNVCGMMPHPERA 197
>Q7V834:PURQ_PROMM Phosphoribosylformylglycinamidine synthase 1 - Prochlorococcus| marinus (strain MIT 9313) Length = 217 Score = 71.6 bits (174), Expect = 1e-11 Identities = 70/235 (29%), Positives = 98/235 (41%), Gaps = 2/235 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 + ++ GSN DR++ A +I L ++ L + GGFSY D L Sbjct: 3 IGVVVFPGSNCDRDVRWAAQGC----LNIPTRFLWHETRDLNGLDAVVLPGGFSYGDYLR 58 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF P+++ EF R LG+CNG Q++ LG +PG Sbjct: 59 CG----AIARF-APVLESLVEFVARGGRV-LGICNGFQVLTELGLLPGA----------- 101 Query: 1308 MSQPRFTHNESGRFECR--FISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 T N S F C ++V +P +M + S L + AHGEGR D L Sbjct: 102 -----LTRNRSLHFICEDALLTVESNRTPWLMGHQRKDS-LTLPIAHGEGRYQCSD-ETL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + LRY + NPNGS IA + + G L LMPHPER+ Sbjct: 155 CQLQDDDAIALRYVN-----------NPNGSVADIAGITNKTGNVLGLMPHPERA 198
>Q8NX93:PURQ_STAAW Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus aureus| (strain MW2) Length = 223 Score = 71.2 bits (173), Expect = 1e-11 Identities = 69/235 (29%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G E + ++ SL+ F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDY-----RETSLSGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I + + LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PIISEVKRLAAEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS-AHGEGRAFFPDGNVL 1481 HN+S F R + I ++ + E I+ AHGEG + D + Sbjct: 101 ------LLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDE--I 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +K+N N + Y NPNGS IA + + G +MPHPER+ Sbjct: 153 YQQLKAN----------NQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERA 197
>Q6GAE5:PURQ_STAAS Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus aureus| (strain MSSA476) Length = 223 Score = 71.2 bits (173), Expect = 1e-11 Identities = 69/235 (29%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G E + ++ SL+ F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDY-----RETSLSGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I + + LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PIISEVKRLAAEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS-AHGEGRAFFPDGNVL 1481 HN+S F R + I ++ + E I+ AHGEG + D + Sbjct: 101 ------LLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDE--I 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +K+N N + Y NPNGS IA + + G +MPHPER+ Sbjct: 153 YQQLKAN----------NQIILKYVNNPNGSYDDIAGIVNKKGNVCGMMPHPERA 197
>Q5HH16:PURQ_STAAC Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus aureus| (strain COL) Length = 223 Score = 71.2 bits (173), Expect = 1e-11 Identities = 69/235 (29%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G E + ++ SL+ F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDY-----RETSLSGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I + + LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PIISEVKRLAAEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS-AHGEGRAFFPDGNVL 1481 HN+S F R + I ++ + E I+ AHGEG + D + Sbjct: 101 ------LLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDE--I 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +K+N N + Y NPNGS IA + + G +MPHPER+ Sbjct: 153 YQQLKAN----------NQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERA 197
>Q2FZJ1:PURQ_STAA8 Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus aureus| (strain NCTC 8325) Length = 223 Score = 71.2 bits (173), Expect = 1e-11 Identities = 69/235 (29%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G E + ++ SL+ F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDY-----RETSLSGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I + + LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PIISEVKRLAAEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS-AHGEGRAFFPDGNVL 1481 HN+S F R + I ++ + E I+ AHGEG + D + Sbjct: 101 ------LLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDE--I 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +K+N N + Y NPNGS IA + + G +MPHPER+ Sbjct: 153 YQQLKAN----------NQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERA 197
>Q2FI10:PURQ_STAA3 Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus aureus| (strain USA300) Length = 223 Score = 71.2 bits (173), Expect = 1e-11 Identities = 69/235 (29%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G E + ++ SL+ F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDY-----RETSLSGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I + + LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PIISEVKRLAAEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS-AHGEGRAFFPDGNVL 1481 HN+S F R + I ++ + E I+ AHGEG + D + Sbjct: 101 ------LLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDE--I 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +K+N N + Y NPNGS IA + + G +MPHPER+ Sbjct: 153 YQQLKAN----------NQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERA 197
>Q9X0X2:PURQ_THEMA Phosphoribosylformylglycinamidine synthase 1 - Thermotoga maritima| Length = 213 Score = 70.9 bits (172), Expect = 2e-11 Identities = 63/238 (26%), Positives = 99/238 (41%), Gaps = 2/238 (0%) Frame = +3 Query: 939 KPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYAD 1118 KP+ ++ GSN DR+ A GFEP + + D L+ ++ I GGFSY D Sbjct: 2 KPRACVVVYPGSNCDRDAYHALEINGFEPSYVGLDDKLD------DYELIILPGGFSYGD 55 Query: 1119 VLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 L ++ + + + + R +G+CNG Q++ +G + G Sbjct: 56 YLRPG-----AVAAREKIAFEIAKAAERGKLI-MGICNGFQILIEMGLLKGA-------- 101 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAF-FPDG 1472 N SG+F C+++ + + ++ + E G + I AHG GR D Sbjct: 102 --------LLQNSSGKFICKWVDLIVENNDTPFTNAFEKGEKIRIPIAHGFGRYVKIDDV 153 Query: 1473 NVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 NV+ LRY D N GS IA + + +G LMPHPER+ Sbjct: 154 NVV----------LRYVKDVN-----------GSDERIAGVLNESGNVFGLMPHPERA 190
>Q8DGX5:PURQ_SYNEL Phosphoribosylformylglycinamidine synthase 1 - Synechococcus| elongatus (Thermosynechococcus elongatus) Length = 241 Score = 70.9 bits (172), Expect = 2e-11 Identities = 64/235 (27%), Positives = 105/235 (44%), Gaps = 2/235 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 V I+ GSN DR++ A+ W + L +++ L ++ I GGFS+ D L Sbjct: 7 VGIVVFPGSNCDRDV--AYVTREILQWPTQL--LWHEETDLGDYDLIVLPGGFSFGDYLR 62 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF+ P++ ++ + + LG+CNG Q++ +PG Sbjct: 63 CG----AIARFS-PIMAAVKD-HAAAGKWVLGICNGFQILTEAKLLPGA----------- 105 Query: 1308 MSQPRFTHNESGRFECRFISVAIG--DSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 N F C + + + + P + G + + + + AHGEG ++ D L Sbjct: 106 -----LVRNRDLHFICDRVHLRLEAKERPWLRAYG-DKTVIRLPIAHGEG-CYYADATTL 158 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +++ + RY D NVT NPNGS IA +C+ G L +MPHPER+ Sbjct: 159 AELEANRQVLFRYADAQGNVTP--ESNPNGSLNNIAGICNAAGNVLGMMPHPERA 211
>Q49WJ2:PURQ_STAS1 Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus| saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) Length = 223 Score = 70.9 bits (172), Expect = 2e-11 Identities = 71/236 (30%), Positives = 106/236 (44%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+++ GSN DR+M ++AA + D N SL F G+ GGFS+ D L Sbjct: 2 KFAVLKFPGSNCDRDM---YNAALKSDVEAEYVDYRN--TSLDGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ ++QF + +P LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVAPITEAVKQFAK-EGKP---VLGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM--EGSTLGIWSAHGEGRAFFPDGNV 1478 HN+S F R S+ + + + F + E T+ AHGEG + Sbjct: 101 ------LLHNDSHLFVSRNESLRVVNH-NTAFTNLYNEDETVVYPVAHGEGHYYCTQD-- 151 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + D +++N N + Y NPNGS IA + + G +MPHPER+ Sbjct: 152 MYDRLEAN----------NQIILKYVNNPNGSFNDIAGIINEQGNVCGMMPHPERA 197
>Q6GI16:PURQ_STAAR Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus aureus| (strain MRSA252) Length = 223 Score = 70.9 bits (172), Expect = 2e-11 Identities = 69/235 (29%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G E + ++ SL+ F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDY-----RETSLSGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I + + LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PVISEVKRLAAEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS-AHGEGRAFFPDGNVL 1481 HN+S F R + I ++ + E I+ AHGEG + D + Sbjct: 101 ------LLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDE--I 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +K+N N + Y NPNGS IA + + G +MPHPER+ Sbjct: 153 YQKLKAN----------NQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERA 197
>Q2YX55:PURQ_STAAB Phosphoribosylformylglycinamidine synthase 1 - Staphylococcus aureus| (strain bovine RF122) Length = 223 Score = 70.9 bits (172), Expect = 2e-11 Identities = 69/235 (29%), Positives = 102/235 (43%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A++ GSN DR+M A +G E + ++ SL+ F G+ GGFS+ D L Sbjct: 2 KFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDY-----RETSLSGFDGVLIPGGFSFGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G AS+ P+I + + LGVCNG Q++ +G +PG Sbjct: 57 RS--GAMASVA---PIISEVKRLAAEGKPV-LGVCNGFQILTEIGLLPGA---------- 100 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS-AHGEGRAFFPDGNVL 1481 HN+S F R + I ++ + E I+ AHGEG + D + Sbjct: 101 ------LLHNDSHLFISRNEELEIVNNHTAFTNLYEQGEKVIYPVAHGEGHYYCTDE--I 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +K+N N + Y NPNGS IA + + G +MPHPER+ Sbjct: 153 YQQLKAN----------NQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERA 197
>Q468N4:PURQ_METBF Phosphoribosylformylglycinamidine synthase 1 - Methanosarcina barkeri| (strain Fusaro / DSM 804) Length = 232 Score = 70.9 bits (172), Expect = 2e-11 Identities = 61/236 (25%), Positives = 106/236 (44%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K+AI++ G+N D+++ + + + ++ LT F G+ GGFSY D L Sbjct: 2 KIAILQFGGTNCDQDVLHVLK----DVVGVDAETVWYKQEDLTGFDGVVVPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I P++ ++ LG+CNG Q++ + G Sbjct: 58 R-----AGAIAARTPIMNSVKKLAAEGKPV-LGICNGFQILTEARVLEGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIG--DSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNV 1478 T NE +F C + ++ + D+P K +G + + AH EG+ F+ + Sbjct: 102 ------LTTNEYPKFRCHWTNLRVETVDTP-FTSKFRKGEVIRMPIAHMEGQ-FYAEEKT 153 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L+++ ++ RY D+ VT+ NPNGS IA + + + LMPHPER+ Sbjct: 154 LAELDENEQVVFRYVDENGKVTD--EANPNGSLENIAGIVNTSRNIFGLMPHPERA 207
>Q28PA2:PURQ_JANSC Phosphoribosylformylglycinamidine synthase 1 - Jannaschia sp. (strain| CCS1) Length = 222 Score = 70.9 bits (172), Expect = 2e-11 Identities = 65/236 (27%), Positives = 100/236 (42%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYADV 1121 K A++ GSN DR+++ F +AGFE + + +++ +L + + GGFSY D Sbjct: 2 KAAVLVFPGSNCDRDLAVGFRSAGFE-----VEMVWHKETALPAGIDVVGIPGGFSYGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P+++ +F + LGVCNG Q++ +PG Sbjct: 57 LR-----CGAIAAQSPIMRAVADFAGQGGHV-LGVCNGFQVLCETRLLPGV--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNV 1478 N +F CR + + + S G G + + AH +G D Sbjct: 102 -------LMRNGGIKFVCRAEPLVVASATSPFTDGYSIGDRIAVPVAHHDGNYQIDD--- 151 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L+ LR D + Y NPNGS IA + S N R L +MPHPER+ Sbjct: 152 ------EGLSALRSED---RIAFTYADNPNGSRADIAGVLSANRRVLGMMPHPERA 198
>Q1J2B6:PURQ_DEIGD Phosphoribosylformylglycinamidine synthase 1 - Deinococcus| geothermalis (strain DSM 11300) Length = 222 Score = 70.9 bits (172), Expect = 2e-11 Identities = 65/236 (27%), Positives = 101/236 (42%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYADV 1121 + A+I+ GSN D + A HAA D + + + +L + F+ GGFSY D Sbjct: 2 RTAVIQFPGSNCDAD---ALHAARLT-LDPDAGFVWHTETALPRGTELVFLPGGFSYGDH 57 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L S +I P++ + R F LGVCNG Q++ G +PG Sbjct: 58 LRSG-----AIAARSPIMAAVKAHAERGG-FVLGVCNGFQVLTEAGLLPGA--------- 102 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNV 1478 + N F C + + + ++ ++ + + G L I AHGEG ++ D Sbjct: 103 -------LSRNRDLHFRCAPVHLRVENAQTVFTRAYQPGQILEIPIAHGEGN-YYADPET 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ + RY D NPNGS IA + + G L +MPHPER+ Sbjct: 155 IARLEAEGRVVFRYVD-----------NPNGSLNDIAGIVNERGNVLGMMPHPERA 199
>Q9KF58:PURQ_BACHD Phosphoribosylformylglycinamidine synthase 1 - Bacillus halodurans| Length = 227 Score = 70.9 bits (172), Expect = 2e-11 Identities = 69/235 (29%), Positives = 98/235 (41%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN D +M A A E D L + + S+ + I GGFSY D L Sbjct: 2 KFAVIVFPGSNCDADMYHAVKDALGEEVDY----LWHTETSVEGYDAILLPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S SI P+++ N LGVCNG Q++ G +PG + Sbjct: 58 RSG-----SIARFSPIMEDVIRAANEGVPV-LGVCNGFQVLLEAGLLPGAML-------- 103 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 NE F C+ + + + ++ + E G T+ I AHGEG ++ D L Sbjct: 104 --------RNEKLTFICKPVELEVQNNDTFFTSEYEQGETITIPVAHGEGN-YYCDDETL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + +N RY D N GS IA + + G L +MPHPER+ Sbjct: 155 KQLEANNQVVFRYTDRVN-----------GSRNHIAGIVNKAGNVLGMMPHPERA 198
>Q2JWK2:PURQ_SYNJA Phosphoribosylformylglycinamidine synthase 1 - Synechococcus sp.| (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime) Length = 225 Score = 70.5 bits (171), Expect = 3e-11 Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 1/238 (0%) Frame = +3 Query: 936 SKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYA 1115 +K + I+ GSN DR+++ P + + +++ L+ + GGFSY Sbjct: 2 AKVRFGIVVFPGSNCDRDVAWVTRGLLGCPTRL----IWHRETDLSGLDVVVLPGGFSYG 57 Query: 1116 DVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLG 1295 D L + A RF P++ E R + LG+CNG Q++ G +PG Sbjct: 58 DYLRAG----ALARF-APVMGSLAEHGARGG-YVLGICNGFQILTEAGLLPGA------- 104 Query: 1296 AGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDG 1472 N + F C + + + G+TL + AHGEGR + D Sbjct: 105 ---------LVRNANLHFICDRVGIRVERQDLPWTSAYPCGATLTLPIAHGEGR-YVCDA 154 Query: 1473 NVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + L + RY P PNGS IA +C P+GR L LMPHPER+ Sbjct: 155 DTLKQLQDRGQIVFRYA----------PVAPNGSVDNIAGICDPSGRILGLMPHPERA 202
>Q2J4N0:PURQ_FRASC Phosphoribosylformylglycinamidine synthase 1 - Frankia sp. (strain| CcI3) Length = 233 Score = 70.5 bits (171), Expect = 3e-11 Identities = 65/243 (26%), Positives = 102/243 (41%), Gaps = 1/243 (0%) Frame = +3 Query: 921 LLSASSKPKVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVG 1100 + A S ++ I+ GS D++ + A AAG EP + D + L + G Sbjct: 1 MTEADSPARIGIVTFPGSLDDQDTALAVRAAGAEPVSLWHGD-----SDLAGVDAVILPG 55 Query: 1101 GFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDI 1280 GFSY D L + A RF+ P++ R LG+CNG Q++ G +PG Sbjct: 56 GFSYGDYLRAG----AIARFS-PMVAALVPAA-RAGLPILGICNGFQVLCEAGLLPGA-- 107 Query: 1281 GGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKG-MEGSTLGIWSAHGEGRA 1457 T N F CR + + + +G +G + I HG+GR Sbjct: 108 --------------LTRNVGLHFVCRDQRLRVEAPGTAWTRGYQDGEEIVIPVKHGDGR- 152 Query: 1458 FFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHP 1637 + +VL+++ + +RY NPNGS IA +C+ + + LMPHP Sbjct: 153 YVAAPDVLAELEAAGRVVVRYVGG----------NPNGSAADIAGICNESRTIVGLMPHP 202 Query: 1638 ERS 1646 E + Sbjct: 203 EHA 205
>Q8RBK6:PURQ_THETN Phosphoribosylformylglycinamidine synthase 1 - Thermoanaerobacter| tengcongensis Length = 224 Score = 70.1 bits (170), Expect = 3e-11 Identities = 64/236 (27%), Positives = 105/236 (44%), Gaps = 1/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN D + A E + +Q+ +L+++ I GGFSY D L Sbjct: 2 KFAVIVFPGSNCDVDCYYAVKDGLGEGVEYVW----HQEKNLSKYDVIMLPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A RF+ P+++ +E + F +G+CNG Q++ G +PG Sbjct: 58 RAG----AIARFS-PVMEAVREEAEK-GKFIIGICNGFQILTEAGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAI-GDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 NE +F C+ +S+ + D + +G + + AHGEG ++ D L Sbjct: 102 ------LRKNEGLKFICKTVSIIVENDKTPFTTRLKKGQEILLPIAHGEGN-YYVDDKTL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSF 1649 ++ +N RY + N NGS IA + + G L +MPHPER++ Sbjct: 155 KELKGNNQIVFRYKE-----------NINGSVERIAGVINKKGNVLGMMPHPERAY 199
>Q9RXT3:PURQ_DEIRA Phosphoribosylformylglycinamidine synthase 1 - Deinococcus| radiodurans Length = 221 Score = 70.1 bits (170), Expect = 3e-11 Identities = 64/236 (27%), Positives = 104/236 (44%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYADV 1121 K A+I+ GSN D + A HAA D + + + +L E + F+ GGFSY D Sbjct: 2 KTAVIQFPGSNCDAD---ALHAARLL-LDDGAQFVWHTETALPEGTELVFLPGGFSYGDH 57 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L S +I P++ + + + LGVCNG Q++ G +PG Sbjct: 58 LRSG-----AIAARSPIMNAVKA-HAEAGGYVLGVCNGFQVLTEAGLLPGA--------- 102 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNV 1478 + N+ F C+ + + + ++ + + G + I AHGEG ++ D Sbjct: 103 -------LSRNKELHFMCKPVHLRVENNATDFSRAYGPGQIIEIPIAHGEGN-YYADAAT 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++++ + RY D NPNGS IA + + G L +MPHPER+ Sbjct: 155 IAELEEGGRVVFRYAD-----------NPNGSLNDIAGIVNERGNVLGMMPHPERA 199
>Q7NL01:PURQ_GLOVI Phosphoribosylformylglycinamidine synthase 1 - Gloeobacter violaceus| Length = 232 Score = 69.3 bits (168), Expect = 6e-11 Identities = 67/237 (28%), Positives = 104/237 (43%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN DR++ +P + + + L GGFSY D L Sbjct: 2 KFAVIVFPGSNCDRDVVTVTRGLLDQPTRLVW----HTEDDLDGCDVAVIPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A RF+ P++Q + R +G+CNG Q++ G +PG Sbjct: 58 RCG----AIARFS-PVMQAVRRHAERGGLV-IGICNGFQVLTEAGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIG--DSPSI-MFKGMEGSTLGIWSAHGEGRAFFPDGN 1475 N +F C +++ + D P + ++ E TL I AHGEG ++ + Sbjct: 102 ------LVRNRDLQFVCDRVALKVERTDLPWVHSYRPGEVITLPI--AHGEG-CYYAEEA 152 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L+++ ++ RYC + V NPNGS IA LC+ +G L +MPHPER+ Sbjct: 153 TLAELEENRQVVFRYCRPDGTIDAVG--NPNGSLHNIAGLCNRHGNVLGMMPHPERA 207
>Q1GVL0:PURQ_SPHAL Phosphoribosylformylglycinamidine synthase 1 - Sphingopyxis| alaskensis (Sphingomonas alaskensis) Length = 221 Score = 68.9 bits (167), Expect = 7e-11 Identities = 69/237 (29%), Positives = 97/237 (40%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAA-GFEPWDITMSDLLNQKASLTEFRG-IAFVGGFSYAD 1118 K A+I GSN DR+M+ A G P + + +++ L E IA GGFSY D Sbjct: 2 KTAVIVFPGSNCDRDMAVALETVTGKAP-----AMVWHRETGLPEGTDFIALPGGFSYGD 56 Query: 1119 VLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 L S A S P+++ E R LGVCNG Q++ G +PG Sbjct: 57 YLRSGAMAARS-----PILRAVAEAAGRGVPV-LGVCNGFQVLTEAGLLPGA-------- 102 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGN 1475 N F CR + + + +S S+ G + I AH +G +F D + Sbjct: 103 --------LMRNAGLNFVCRTVPLKVENSQSLFTAAYGAGEEIAIPVAHHDGN-YFADAD 153 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L + RY D N GS IA + + G L +MPHPER+ Sbjct: 154 TLDRIEGEGRVAFRYLDGVN-----------GSARDIAGVLNDAGNVLGMMPHPERA 199
>Q218N7:PURQ_RHOPB Phosphoribosylformylglycinamidine synthase 1 - Rhodopseudomonas| palustris (strain BisB18) Length = 233 Score = 68.9 bits (167), Expect = 7e-11 Identities = 65/234 (27%), Positives = 98/234 (41%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFH-AAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 K AI+ G N +R+M+ A A+G EP + +D K + + GGFSY D Sbjct: 2 KSAILVFPGINRERDMARALQLASGSEPAMVWHADTELPKGTDL----VVVPGGFSYGDY 57 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P++ ++F + LGVCNG Q++ G +PG Sbjct: 58 LR-----CGAIAARAPVMDAVRKFAS-DGGLVLGVCNGFQILCESGLLPGV--------- 102 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNV 1478 N +F C + + + S + +G G + + AHGEG + D Sbjct: 103 -------LMRNARLKFICHDVHLRVERSDTPFTRGYNAGQVIRVPVAHGEGN-YEADEET 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L + RYC + V E + N NG+ IA + S G L +MPHPE Sbjct: 155 LQRLEGDGRVLYRYCSASGEVGEAH--NINGAAASIAGIVSERGNVLGMMPHPE 206
>Q1IPG4:PURQ_ACIBL Phosphoribosylformylglycinamidine synthase 1 - Acidobacteria| bacterium (strain Ellin345) Length = 231 Score = 68.6 bits (166), Expect = 1e-10 Identities = 57/235 (24%), Positives = 104/235 (44%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K ++ GSN D + +P ++ L ++ L I GGF+Y D L Sbjct: 2 KFGVLIFPGSNCDHDAHWVLGQVAKQP----VTFLWHESHDLENCDAIVVPGGFAYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A +F+ P+++ ++F ++ +G+CNG Q++ G +PG Sbjct: 58 RTG----AIAKFS-PVMEAVRKFADKGGLV-IGICNGFQILTESGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 NE ++ C+ +++ + + + +G++ G L + H EG + D L Sbjct: 102 ------LLRNEGLKYICKPVNIRVETTDAPFTQGLKKGEVLQVPIGHMEGN-YVCDDATL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +++ K + RY +T NPNGS IA +C+ L +MPHPER+ Sbjct: 155 AELKKQDRIVFRYATPDGQITR--EANPNGSIENIAGICNEGRNVLGMMPHPERA 207
>Q6FZJ0:PURQ_BARQU Phosphoribosylformylglycinamidine synthase 1 - Bartonella quintana| (Rochalimaea quintana) Length = 223 Score = 68.2 bits (165), Expect = 1e-10 Identities = 63/234 (26%), Positives = 100/234 (42%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFH-AAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 K AII+ G N D++M A H G EP I ++ +++ + I GGFSY D Sbjct: 2 KTAIIQLPGLNRDQDMLVALHHITGVEPIKIWQTE-----STIPDVDVIVIPGGFSYGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P++Q +E + T +G+CNG Q++ +PG Sbjct: 57 LR-----CGAIGARTPVLQAVREKAQKGVTV-IGICNGFQILLEARLLPGA--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNV 1478 N S +F CR I + + ++ + + +G + AH +G +F D Sbjct: 102 -------LMRNTSLKFVCREIKLEVVNANTRFSRYYSKGQIIRCPVAHHDGN-YFVDNET 153 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L + + RY ++ N PNGS IA + + G L +MPHPE Sbjct: 154 LKQMEDNEQIVFRYAENTN---------PNGSIRDIAGIINKAGNILGMMPHPE 198
>Q7U831:PURQ_SYNPX Phosphoribosylformylglycinamidine synthase 1 - Synechococcus sp.| (strain WH8102) Length = 217 Score = 67.8 bits (164), Expect = 2e-10 Identities = 66/235 (28%), Positives = 95/235 (40%), Gaps = 2/235 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 + ++ GSN DR++ A P + +++ L+ + GGFSY D L Sbjct: 3 IGVLVFPGSNCDRDVQWATEGCLGMP----TRRIWHEETDLSGLDAVVLPGGFSYGDYLR 58 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF P +Q F + LG+CNG Q++ LG +PG Sbjct: 59 CG----AIARF-APALQALLGFAAQGGRV-LGICNGFQVLTELGLLPGA----------- 101 Query: 1308 MSQPRFTHNESGRFECRF--ISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 T N F C + V +P + G + L + AHGEGR D Sbjct: 102 -----LTRNRDLHFICEDAPLQVVSSRTPWLEHYGTD-KALTLPIAHGEGRYQCSDDT-- 153 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L+ DA+ + Y NPNGS IA + + +G L LMPHPER+ Sbjct: 154 ----------LKQLQDADAIALRYQANPNGSVADIAGITNDSGNVLGLMPHPERA 198
>Q2RWI2:PURQ_RHORT Phosphoribosylformylglycinamidine synthase 1 - Rhodospirillum rubrum| (strain ATCC 11170 / NCIB 8255) Length = 230 Score = 67.8 bits (164), Expect = 2e-10 Identities = 68/232 (29%), Positives = 93/232 (40%), Gaps = 2/232 (0%) Frame = +3 Query: 951 AIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLDS 1130 AII G+N +R+M+ A G + + A L + GGFSY D L S Sbjct: 4 AIIVFPGTNRERDMAKALTLVGGKAPQMVWHRDSALPAGLDL---VVLPGGFSYGDYLRS 60 Query: 1131 AKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGDM 1310 A S P++ + F LGVCNG Q++ G +PG Sbjct: 61 GAMGARS-----PILDAVRRFAEAGGHV-LGVCNGFQILTEAGLLPGA------------ 102 Query: 1311 SQPRFTHNESGRFECRFISVAIGD--SPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVLS 1484 N RF CR + + + SP G+ G + AH +G +F D L+ Sbjct: 103 ----LMRNRDLRFICRDVHLRVETIASPYTSAYGL-GEVARVPVAHHDGN-YFADDATLA 156 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 + + RYC V E PNGS IA + S N R L +MPHPE Sbjct: 157 QLADEDRVAFRYCAADGTVGEAS--TPNGSRDAIAGILSANRRVLGMMPHPE 206
>Q67KF7:PURQ_SYMTH Phosphoribosylformylglycinamidine synthase 1 - Symbiobacterium| thermophilum Length = 235 Score = 67.4 bits (163), Expect = 2e-10 Identities = 54/199 (27%), Positives = 85/199 (42%), Gaps = 1/199 (0%) Frame = +3 Query: 1053 NQKASLTEFRGIAFVGGFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCN 1232 ++ LT + + GGF+Y D + S ++ P+++ EF R LG+CN Sbjct: 34 HEARDLTPYDAVVIPGGFTYGDRVRSG-----ALACRAPVMEAVAEFAARGGLV-LGICN 87 Query: 1233 GCQLMALLGWVPGPDIGGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGM 1409 G Q++ G +PG F N GR+ C + V + ++ + Sbjct: 88 GFQILTEAGLLPGG----------------FRPNAHGRYRCGWSRVRVENAATPFTLACR 131 Query: 1410 EGSTLGIWSAHGEGRAFFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIA 1589 G L I +HG G + D + L + ++ RYC VT NPNGS IA Sbjct: 132 PGQVLKIPVSHGMGN-YQADPDTLRALSENQQVLFRYCTPEGAVTP--GANPNGSAENIA 188 Query: 1590 ALCSPNGRHLALMPHPERS 1646 + + G +MPHPER+ Sbjct: 189 GIVNRTGNVAGVMPHPERA 207
>Q1MG27:PURQ_RHIL3 Phosphoribosylformylglycinamidine synthase 1 - Rhizobium| leguminosarum bv. viciae (strain 3841) Length = 223 Score = 67.4 bits (163), Expect = 2e-10 Identities = 62/233 (26%), Positives = 99/233 (42%), Gaps = 1/233 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+++ G N DR+M AA +P +T + + + + I GGFSY D L Sbjct: 2 KSAVVQLPGLNRDRDMIAALTKISGQP-PVT---IWQTETEIPDVDLIVIPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 +I P++Q + ++ LGVCNG Q++ G +PG Sbjct: 58 R-----CGAIAARMPVMQAIIDKASK-GVKVLGVCNGFQILVEAGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNVL 1481 N S +F CR I + + ++ + + +G + AH +G +F D L Sbjct: 102 ------LMRNSSLKFVCREIKLEVVNAETDFTRAYAQGQVIRCPVAHHDGN-YFADDATL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 + + + RY + N PNGS IAA+ + G L +MPHPE Sbjct: 155 AAIEGNGQVVFRYAEGTN---------PNGSINDIAAVMNEKGNVLGMMPHPE 198
>Q88U24:PURQ_LACPL Phosphoribosylformylglycinamidine synthase 1 - Lactobacillus| plantarum Length = 225 Score = 67.4 bits (163), Expect = 2e-10 Identities = 75/243 (30%), Positives = 104/243 (42%), Gaps = 6/243 (2%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDI--TMSDLLNQKA-SLTEFRGIAFVGGFSYA 1115 K A+ GSN D +M A DI +DL+ A SL + + GGFSY Sbjct: 2 KFAVPVFPGSNCDHDMVNALR-------DILHVTADLIPATATSLAGYDAVVLPGGFSYG 54 Query: 1116 DVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLG 1295 D L S A RF P++ F N +G+CNG Q++ G +PG Sbjct: 55 DYLRSG----AIARF-APIMPAVIAFANAGKPV-IGICNGFQVLTEAGLLPGA------- 101 Query: 1296 AGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGST--LGIWSAHGEGRAFFPD 1469 N S +F C+ + I + +I F GST + + AHGEG + + Sbjct: 102 ---------LQANRSAKFICQDSPLRIANHETI-FTTAYGSTDQISLPIAHGEGNYYCDE 151 Query: 1470 GNVLSDVVKSNLAPLRYCDDANN-VTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + LA LR AN+ + Y NPNGS IA + + G L +MPHPER+ Sbjct: 152 ---------ATLAQLR----ANHQIIFEYVENPNGSTANIAGITNEAGNVLGMMPHPERA 198 Query: 1647 FMM 1655 M Sbjct: 199 VEM 201
>Q5WJ87:PURQ_BACSK Phosphoribosylformylglycinamidine synthase 1 - Bacillus clausii| (strain KSM-K16) Length = 227 Score = 67.0 bits (162), Expect = 3e-10 Identities = 71/237 (29%), Positives = 99/237 (41%), Gaps = 3/237 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I GSN D +M A E + + + + SL F + GGFS+ D L Sbjct: 2 KFAVIVFPGSNCDADMYHAIKDGLGEEVEY----VFHTETSLDGFDAVLLPGGFSHGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S G A P + Q E +P LGVCNG Q++ G +PG Sbjct: 58 RS--GAIARFAPIMPAVIQAAEA-GKP---VLGVCNGFQVLLEAGLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 N +F CR + + + ++ ++ G E G T+ I AHGEG D Sbjct: 102 ------MKRNIDLKFVCRTVELVVENNETMFSSGYEQGQTIRIPVAHGEGNYECDD---- 151 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNP--NGSPLGIAALCSPNGRHLALMPHPERS 1646 LA LR N V+ +N NGS IA + + G L +MPHPER+ Sbjct: 152 -----ETLAKLR-----ENKQIVFRYNEHVNGSKGDIAGITNERGNVLGMMPHPERA 198
>Q98NN0:PURQ_RHILO Phosphoribosylformylglycinamidine synthase 1 - Rhizobium loti| (Mesorhizobium loti) Length = 222 Score = 66.6 bits (161), Expect = 4e-10 Identities = 64/234 (27%), Positives = 98/234 (41%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAF-HAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 K A++ G N DR+M AA +G P + +D + + IA GGFS+ D Sbjct: 2 KSAVVLLPGLNRDRDMIAALTKISGKPPVTVWQTD-----TEIPDVDLIAIPGGFSFGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P+++ E + T +GVCNG Q++ G +PG Sbjct: 57 LR-----CGAIAARMPVMRAVAEKAAKGVTV-IGVCNGFQILVEAGLLPGA--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNV 1478 N S +F CR I + I ++ ++ + + G + AH +G +F D Sbjct: 102 -------LMRNTSLKFVCRQIKLEITNANTMFTRRYQPGQVIRSPVAHHDGN-YFADAET 153 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L+ + RY + N PNGS IA + + G L LMPHPE Sbjct: 154 LARLEGEGQVVFRYAEGTN---------PNGSINDIAGIINEQGNVLGLMPHPE 198
>Q8G180:PURQ_BRUSU Phosphoribosylformylglycinamidine synthase 1 - Brucella suis| Length = 223 Score = 66.6 bits (161), Expect = 4e-10 Identities = 63/235 (26%), Positives = 98/235 (41%), Gaps = 3/235 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAF-HAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYAD 1118 K A+I G N DR+M AA G P + +D S+ + + + GGFSY D Sbjct: 2 KSAVILLPGLNRDRDMIAALTKITGQAPVTVWQTD-----TSIPDDVDLILIPGGFSYGD 56 Query: 1119 VLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 L +I P++Q +E ++ +GVCNG Q++ G +PG Sbjct: 57 YLR-----CGAIAARMPVMQAVREKADK-GVMVMGVCNGFQILLEAGLLPGA-------- 102 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 N S +F CR + + + ++ + +G + G + AH +G +F D Sbjct: 103 --------LMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGN-YFADAE 153 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L + RY + N PNGS IA + + G L +MPHPE Sbjct: 154 TLKRLEGEGQVVFRYAEGTN---------PNGSVNDIAGIVNARGNVLGMMPHPE 199
>Q9PHZ7:PURQ_CAMJE Phosphoribosylformylglycinamidine synthase 1 - Campylobacter jejuni| Length = 223 Score = 66.2 bits (160), Expect = 5e-10 Identities = 64/235 (27%), Positives = 98/235 (41%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 KVAIIR G+N + + + AF G + I + A L + GGFSY D L Sbjct: 2 KVAIIRFPGTNCEFDTTYAFEKLGVKT-QIVWHEEKEFDADL-----VVLPGGFSYGDYL 55 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A+I P +Q + + + LG+CNG Q++ G + G Sbjct: 56 R-----CAAIAKLAPAMQGVFN-HAKKGGYILGICNGFQILLESGLLKGA---------- 99 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 HN + F + S+ + + + K + + + AHGEG ++ D L Sbjct: 100 ------MKHNNNLSFISKNQSLRVVSNDNAFLKNFKKDEIINLPIAHGEGN-YYADETTL 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ +L L+Y NPNGS IA +C N + LMPHPER+ Sbjct: 153 KELQDKDLIILKYEP-----------NPNGSVFDIAGICDENKKIFGLMPHPERA 196
>Q7M9X7:PURQ_WOLSU Phosphoribosylformylglycinamidine synthase 1 - Wolinella succinogenes| Length = 218 Score = 65.5 bits (158), Expect = 8e-10 Identities = 67/236 (28%), Positives = 106/236 (44%), Gaps = 3/236 (1%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLL-NQKASLTEFRGIAFV-GGFSYADV 1121 +A++R G+N + +M +F G E S L+ +Q+ L + + + GGFSY D Sbjct: 3 IAVLRFPGTNCEFDMLHSFKLLGVE------SHLVWHQEKELPKGTHLVVIPGGFSYGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L S A RF+ P++Q Y + LG+CNG Q++ G +PG Sbjct: 57 LRSG----AIARFS-PIMQAVIR-YAKEGGKVLGICNGFQILVESGLLPGA--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGS-TLGIWSAHGEGRAFFPDGNV 1478 NE+ F +F +A+ + + + S TL I AH +G +F D Sbjct: 102 -------LRRNENLHFVSKFQKLAVVSNNNPFLREYAVSETLNIPIAHADGN-YFIDAKG 153 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 L ++ +++ L Y + NPNGS IA +C+ LMPHPER+ Sbjct: 154 LEELKENDQILLTYQGE----------NPNGSIESIAGVCNKEKSVFGLMPHPERA 199
>Q0S774:PURQ_RHOSR Phosphoribosylformylglycinamidine synthase 1 - Rhodococcus sp.| (strain RHA1) Length = 225 Score = 65.1 bits (157), Expect = 1e-09 Identities = 67/235 (28%), Positives = 93/235 (39%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 +V +I G+ D + + A AG E + D A L + GGFSY D L Sbjct: 4 RVGVITFPGTLDDVDAARAVTLAGGEAVSLWHGD-----ADLKGVDAVIVPGGFSYGDYL 58 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A RF + + Q LG+CNG Q++ G +PG Sbjct: 59 RCG----AIARFAPVMGKVVQAAQGGMPV--LGICNGFQVLCEAGLLPGA---------- 102 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 T NE F CR + + + + E G+ + + GEGR + NVL Sbjct: 103 ------LTRNEGLHFICRDEWLKVEATSTAWTSRYESGAEILVPLKSGEGR-YQASENVL 155 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ RY D NPNGS GIA + S NGR + LMPHPE + Sbjct: 156 DELEGEGRVVFRYVGD----------NPNGSQRGIAGISSANGRVVGLMPHPEHA 200
>Q2K7X5:PURQ_RHIEC Phosphoribosylformylglycinamidine synthase 1 - Rhizobium etli (strain| CFN 42 / ATCC 51251) Length = 223 Score = 65.1 bits (157), Expect = 1e-09 Identities = 62/234 (26%), Positives = 98/234 (41%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAF-HAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 K A+++ G N DR+M AA +G +P I ++ + + I GGFSY D Sbjct: 2 KSAVVQLPGLNRDRDMIAALTKISGHQPVTIWQTE-----TEIPDVDLIVIPGGFSYGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P++Q + + LGVCNG Q++ G +PG Sbjct: 57 LR-----CGAIAARMPVMQAIIDKAAK-GVKVLGVCNGFQILVEAGLLPGA--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNV 1478 N S +F CR I + + ++ + + +G + AH +G +F D Sbjct: 102 -------LMRNASLKFVCREIKLKVVNAETDFTRAYAQGQVIRCPVAHHDGN-YFADEAT 153 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L+ + + RY + N PNGS IA + + G L +MPHPE Sbjct: 154 LAKIEGNGQVLFRYAEGTN---------PNGSINDIAGVMNEKGNVLGMMPHPE 198
>Q89IB6:PURQ_BRAJA Phosphoribosylformylglycinamidine synthase 1 - Bradyrhizobium| japonicum Length = 233 Score = 65.1 bits (157), Expect = 1e-09 Identities = 65/235 (27%), Positives = 97/235 (41%), Gaps = 3/235 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHA-AGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYAD 1118 K AI+ G N DR+M+ A +G EP + + + + SL + V GGFSY D Sbjct: 2 KAAILVFPGINRDRDMARALRLISGSEP-----AMVWHAETSLPAGTDLVVVPGGFSYGD 56 Query: 1119 VLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 L +I P++ ++ Y LGVCNG Q++ G +PG Sbjct: 57 YLR-----CGAIAARAPVMDAVRD-YAAKGGLVLGVCNGFQILCESGLLPGV-------- 102 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 N +F CR + + + S + +G G + + AHGEG + D Sbjct: 103 --------LMRNAQLKFICRDVHLRVERSDTPFTRGYNAGQVIRVPVAHGEGN-YEADEE 153 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 + + RYC V E N NG+ IA + + G L +MPHPE Sbjct: 154 TIQRLEGEGRVLYRYCSAEGVVDEAA--NINGAAHSIAGIVNDKGNVLGMMPHPE 206
>Q8YGN4:PURQ_BRUME Phosphoribosylformylglycinamidine synthase 1 - Brucella melitensis| Length = 223 Score = 64.7 bits (156), Expect = 1e-09 Identities = 62/235 (26%), Positives = 98/235 (41%), Gaps = 3/235 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAF-HAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYAD 1118 K A+I G N +R+M AA G P + +D S+ + + + GGFSY D Sbjct: 2 KSAVILLPGLNRNRDMIAALTKITGQAPVTVWQTD-----TSIPDDVDLILIPGGFSYGD 56 Query: 1119 VLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 L +I P++Q +E ++ +GVCNG Q++ G +PG Sbjct: 57 YLR-----CGAIAARMPVMQAVREKADK-GVMVMGVCNGFQILLEAGLLPGA-------- 102 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 N S +F CR + + + ++ + +G + G + AH +G +F D Sbjct: 103 --------LMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGN-YFADAE 153 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L + RY + N PNGS IA + + G L +MPHPE Sbjct: 154 TLKRLEGEGQVVFRYAEGTN---------PNGSVNDIAGIVNARGNVLGMMPHPE 199
>Q57DR5:PURQ_BRUAB Phosphoribosylformylglycinamidine synthase 1 - Brucella abortus| Length = 223 Score = 64.7 bits (156), Expect = 1e-09 Identities = 62/235 (26%), Positives = 98/235 (41%), Gaps = 3/235 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAF-HAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYAD 1118 K A+I G N +R+M AA G P + +D S+ + + + GGFSY D Sbjct: 2 KSAVILLPGLNRNRDMIAALTKITGQAPVTVWQTD-----TSIPDDVDLILIPGGFSYGD 56 Query: 1119 VLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 L +I P++Q +E ++ +GVCNG Q++ G +PG Sbjct: 57 YLR-----CGAIAARMPVMQAVREKADK-GVMVMGVCNGFQILLEAGLLPGA-------- 102 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 N S +F CR + + + ++ + +G + G + AH +G +F D Sbjct: 103 --------LMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGN-YFADAE 153 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L + RY + N PNGS IA + + G L +MPHPE Sbjct: 154 TLKRLEGEGQVVFRYAEGTN---------PNGSVNDIAGIVNARGNVLGMMPHPE 199
>Q2YNG3:PURQ_BRUA2 Phosphoribosylformylglycinamidine synthase 1 - Brucella abortus| (strain 2308) Length = 223 Score = 64.7 bits (156), Expect = 1e-09 Identities = 62/235 (26%), Positives = 98/235 (41%), Gaps = 3/235 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAF-HAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYAD 1118 K A+I G N +R+M AA G P + +D S+ + + + GGFSY D Sbjct: 2 KSAVILLPGLNRNRDMIAALTKITGQAPVTVWQTD-----TSIPDDVDLILIPGGFSYGD 56 Query: 1119 VLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 L +I P++Q +E ++ +GVCNG Q++ G +PG Sbjct: 57 YLR-----CGAIAARMPVMQAVREKADK-GVMVMGVCNGFQILLEAGLLPGA-------- 102 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 N S +F CR + + + ++ + +G + G + AH +G +F D Sbjct: 103 --------LMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGN-YFADAE 153 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L + RY + N PNGS IA + + G L +MPHPE Sbjct: 154 TLKRLEGEGQVVFRYAEGTN---------PNGSVNDIAGIVNARGNVLGMMPHPE 199
>Q8ES97:PURQ_OCEIH Phosphoribosylformylglycinamidine synthase 1 - Oceanobacillus| iheyensis Length = 228 Score = 64.3 bits (155), Expect = 2e-09 Identities = 66/236 (27%), Positives = 94/236 (39%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREM-SAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 K A+I GSN DR+M A AG E + ++ L GI GGFSY D Sbjct: 2 KFAVIVFPGSNCDRDMYHAVKEVAGAEAELVWYTET----DKLEGVDGILLPGGFSYGDY 57 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L S S+ ++ + +E + LGVCNG Q++ G +PG Sbjct: 58 LRSG-----SMASTSDVMHKIREHAAKGKPV-LGVCNGFQILTESGLLPGA--------- 102 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWS-AHGEGRAFFPDGNV 1478 N+ F C + + D+ + E + + AHGEG F + Sbjct: 103 -------LMRNKHLSFMCHQEELVVEDNQTFFTSLYEKKEVVRFPIAHGEGSYFCDE--- 152 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 A L+ N + Y NPNGS IA + + G L +MPHPER+ Sbjct: 153 ---------ATLKELQANNQIVFTYKNNPNGSIENIAGIRNKQGNVLGMMPHPERA 199
>Q8KCS5:PURQ_CHLTE Phosphoribosylformylglycinamidine synthase 1 - Chlorobium tepidum| Length = 234 Score = 64.3 bits (155), Expect = 2e-09 Identities = 64/235 (27%), Positives = 100/235 (42%), Gaps = 2/235 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHA-AGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 V I+ GSN D + A + G +P + +D L + GGFSY D L Sbjct: 6 VGIVVFPGSNCDHDTEYAVASFPGVKPVMLWHND-----HDLKGCDAVILPGGFSYGDYL 60 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A RF+ P++++ +F + LG+CNG Q++ G + G I Sbjct: 61 RCG----AIARFS-PIMREVIDFAGKGRPV-LGICNGFQVLVECGLLEGALI-------- 106 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMF-KGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 N RF R ++++ ++ +I + +G L + AHGEG ++ + Sbjct: 107 --------RNAGRRFVSRQTTISVANNATIFTDRYQKGEVLRVPVAHGEGN-YYASPETI 157 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + RY D N T FN GS IA + + G L LMPHPER+ Sbjct: 158 ESLESNGQVVFRYTDAWGNATAEANFN--GSMNNIAGIVNKQGNVLGLMPHPERA 210
>Q2IG97:PURQ_ANADE Phosphoribosylformylglycinamidine synthase 1 - Anaeromyxobacter| dehalogenans (strain 2CP-C) Length = 218 Score = 64.3 bits (155), Expect = 2e-09 Identities = 62/236 (26%), Positives = 96/236 (40%), Gaps = 2/236 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREM-SAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 +V I+ GSN D + H G E + D L ++ + GGFSY D Sbjct: 2 RVGILTFPGSNCDHDCYHVVKHVMGAEAQYVWHKDRLPEQLD-----AVVVPGGFSYGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L A RF+ P+I F + LG+CNG Q++ G +PG Sbjct: 57 LRCG----ALARFS-PVIADLVTFAEKGGPV-LGICNGFQILCEAGLLPGV--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 N S ++ C+ +++ + + + +G+ G +L + AH EG +F D L Sbjct: 102 -------LMRNASLKYICKDVTIRVEGQETPVTRGLAGQSLTMPIAHAEGN-YFADPETL 153 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRH-LALMPHPERS 1646 + RY A PNGS IA + R+ + LMPHP+R+ Sbjct: 154 DRLEGEGRVVFRYVGGA----------PNGSARDIAGISGGPARNVVGLMPHPDRA 199
>Q11IV0:PURQ_MESSB Phosphoribosylformylglycinamidine synthase 1 - Mesorhizobium sp.| (strain BNC1) Length = 222 Score = 63.5 bits (153), Expect = 3e-09 Identities = 63/234 (26%), Positives = 94/234 (40%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAF-HAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 K A+I+ G N DR+M AA +G P + ++ L E I GGFSY D Sbjct: 2 KSAVIQLPGLNRDRDMIAALTKISGQAPVTVWQTE-----TELPEVDLIVIPGGFSYGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P+++ E + +GVCNG Q++ G +PG Sbjct: 57 LR-----CGAIAARMPVMKAVAEKAAK-GVLVIGVCNGFQILLEAGLLPGA--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNV 1478 N S +F CR + + + ++ + + G + AH +G FF Sbjct: 102 -------LMRNASLKFVCREVKLQVANANTAFTRAYAPGQIIRCPVAHHDGN-FFAAPET 153 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L+ + RY + N PNGS IA + + G L LMPHPE Sbjct: 154 LARIEGEGQVAFRYAEGTN---------PNGSINDIAGIVNGAGNVLGLMPHPE 198
>Q5Z2C8:PURQ_NOCFA Phosphoribosylformylglycinamidine synthase 1 - Nocardia farcinica| Length = 225 Score = 63.2 bits (152), Expect = 4e-09 Identities = 66/235 (28%), Positives = 96/235 (40%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++ +I G+ D + A AG E ++ +D A L + + GGFSY D L Sbjct: 4 RIGVITFPGTLDDVDAVRAVRLAGAEAVNLWHAD-----ADLKQVDAVIVPGGFSYGDYL 58 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A RF P++ + + LG+CNG Q++ G +PG Sbjct: 59 RAG----AIARF-APVMGEVVRAAEQGMPV-LGICNGFQVLCEAGLLPGA---------- 102 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 T NE F CR + + + E G+ + I GEGR + VL Sbjct: 103 ------LTRNEGLHFICRDQWLTVESVSTAWTSRYEPGAQILIPLKSGEGR-YQAAPAVL 155 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ RY D NPNGS GIA + S NGR + LMPHPE + Sbjct: 156 DELEGEGRVVFRYSGD----------NPNGSQRGIAGISSANGRVVGLMPHPEHA 200
>Q9ZB07:PURQ_LACLC Phosphoribosylformylglycinamidine synthase 1 - Lactococcus lactis| subsp. cremoris (Streptococcus cremoris) Length = 226 Score = 63.2 bits (152), Expect = 4e-09 Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I+ GSN D ++ A + D + SL F G+ GGFSY D L Sbjct: 2 KFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHD----EKSLAGFDGVLIPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 G AS P I++ + +P G CNG Q++ G +PG I Sbjct: 58 RC--GAIASFANIMPEIKRLAK-EGKP---VFGTCNGFQILVESGLLPGVLI-------- 103 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 NE +F ++ + + ++ S + + + + + AHGEG+ + D L Sbjct: 104 --------RNEGLKFVSKWQVLKVENNQSNFTTEYAKDALINLPIAHGEGQ-YVADEATL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +++ ++ Y D+ NPNGS IA + + G L +MPHPER+ Sbjct: 155 AELKENGQIVFTYADE----------NPNGSVENIAGIINKEGNVLGMMPHPERA 199
>Q3ST24:PURQ_NITWN Phosphoribosylformylglycinamidine synthase 1 - Nitrobacter| winogradskyi (strain Nb-255 / ATCC 25391) Length = 233 Score = 62.4 bits (150), Expect = 7e-09 Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 3/235 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFH-AAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYAD 1118 K A++ G N +R+M+ A +G EP + + + + SL E + GGFSY D Sbjct: 2 KSAVLVFPGINRERDMARALRLVSGREP-----AMVWHAETSLPEGTDLVVAPGGFSYGD 56 Query: 1119 VLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 L +I P++ + F + LGVCNG Q++ G +PG Sbjct: 57 YLR-----CGAIAARAPVMDAVRAFAS-DGGLVLGVCNGFQILCESGLLPGI-------- 102 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGN 1475 N +F C + + + S + +G G + + AHGEG + D + Sbjct: 103 --------LMRNARLKFICHDVHLRVERSDTPFTRGYNAGQVIRVPVAHGEGN-YAADED 153 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 + + RYC + V + + N NG+ IA + + G L +MPHPE Sbjct: 154 TIRRLEGEGRVLYRYCSASGEVGDTH--NINGAAQSIAGIVNERGNVLGMMPHPE 206
>Q9CFE7:PURQ_LACLA Phosphoribosylformylglycinamidine synthase 1 - Lactococcus lactis| subsp. lactis (Streptococcus lactis) Length = 223 Score = 62.4 bits (150), Expect = 7e-09 Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K A+I+ GSN D ++ A + D + SL F G+ GGFSY D L Sbjct: 2 KFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHD----EKSLAGFDGVLIPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 G AS P I++ + +P G CNG Q++ G +PG I Sbjct: 58 RC--GAIASFANIMPEIKRLAK-EGKP---VFGTCNGFQILVESGLLPGVLI-------- 103 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 NE +F ++ ++ + ++ S + + + + + AHGEG+ + D L Sbjct: 104 --------RNEGLKFVSKWQALKVENNQSNFTTEYAKDALINLPIAHGEGQ-YVADEAQL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +++ + Y D+ NPNGS IA + + G L +MPHPER+ Sbjct: 155 AELKANGQIIFTYADE----------NPNGSVENIAGIVNKEGNVLGMMPHPERA 199
>Q9RXT4:PURL_DEIRA Phosphoribosylformylglycinamidine synthase II - Deinococcus| radiodurans Length = 747 Score = 62.4 bits (150), Expect = 7e-09 Identities = 48/181 (26%), Positives = 80/181 (44%), Gaps = 3/181 (1%) Frame = +3 Query: 261 PDITLTVTPDLKL-GKDGVLLHVDLAKG-KRRLGCSALAQAFDQIGNDCPDIEDVPYLKK 434 PD+T+ + +LK G+ +LL KG +G S + + D+ +K Sbjct: 560 PDVTVRASLNLKAAGQTLLLLGHRAEKGWSDSIGASQYLETVHGLEAGQVPPVDLDLAQK 619 Query: 435 VFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEEL 614 V + L+ L HD ++GGL V + EMA AG G+N++++ + L E Sbjct: 620 VVDGTLALIRAGLTDTAHDCAEGGLAVALAEMAIAGGLGLNVSLDAPASVRADALLFGEA 679 Query: 615 GLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGE-VRLKERTSDLRDLWE 791 + V ++D KL G+ V+GE AP++ + + V L L+ WE Sbjct: 680 HSRVIVAVEDAAAAGAKLDELGLPYAVLGETVEAPKVTIAAPAQHVHLSVNLESLKTAWE 739 Query: 792 E 794 E Sbjct: 740 E 740
>Q31Q18:PURQ_SYNP7 Phosphoribosylformylglycinamidine synthase 1 - Synechococcus sp.| (strain PCC 7942) (Anacystis nidulans R2) Length = 221 Score = 62.0 bits (149), Expect = 9e-09 Identities = 64/234 (27%), Positives = 94/234 (40%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 V +I GSN DR++ + AG M + +++ L+ I GGFSY D L Sbjct: 3 VGVIVFPGSNCDRDVQ--WVTAGLLGQSTRM--IWHEERDLSGLDLIVVPGGFSYGDYLR 58 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF+ + Q + LG+CNG Q++ +G +PG Sbjct: 59 CG----AIARFSPAM--QATVAFAEAGGLVLGICNGFQILTEVGLLPGA----------- 101 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKG-MEGSTLGIWSAHGEGRAFFPDGNVLS 1484 N F C + + S + +G L + AHGEGR + D L+ Sbjct: 102 -----LVRNRDLHFRCETTPLRVERSDRPWSRTYQQGQILNLPIAHGEGR-YHADPATLA 155 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + RY D NPNGS IA + + G L +MPHPER+ Sbjct: 156 ALEANGQVLFRYLD-----------NPNGSCNDIAGITNVAGNVLGMMPHPERA 198
>Q5N459:PURQ_SYNP6 Phosphoribosylformylglycinamidine synthase 1 - Synechococcus sp.| (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) Length = 221 Score = 62.0 bits (149), Expect = 9e-09 Identities = 64/234 (27%), Positives = 94/234 (40%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 V +I GSN DR++ + AG M + +++ L+ I GGFSY D L Sbjct: 3 VGVIVFPGSNCDRDVQ--WVTAGLLGQSTRM--IWHEERDLSGLDLIVVPGGFSYGDYLR 58 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 A RF+ + Q + LG+CNG Q++ +G +PG Sbjct: 59 CG----AIARFSPAM--QATVAFAEAGGLVLGICNGFQILTEVGLLPGA----------- 101 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKG-MEGSTLGIWSAHGEGRAFFPDGNVLS 1484 N F C + + S + +G L + AHGEGR + D L+ Sbjct: 102 -----LVRNRDLHFRCETTPLRVERSDRPWSRTYQQGQILNLPIAHGEGR-YHADPATLA 155 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + RY D NPNGS IA + + G L +MPHPER+ Sbjct: 156 ALEANGQVLFRYLD-----------NPNGSCNDIAGITNVAGNVLGMMPHPERA 198
>P65902:PURQ_MYCTU Phosphoribosylformylglycinamidine synthase 1 - Mycobacterium| tuberculosis Length = 224 Score = 62.0 bits (149), Expect = 9e-09 Identities = 63/235 (26%), Positives = 95/235 (40%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++ ++ G+ D + + A G E + +D A L + GGFSY D L Sbjct: 4 RIGVVTFPGTLDDVDAARAARQVGAEVVSLWHAD-----ADLKGVDAVVVPGGFSYGDYL 58 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A RF P++ + +R LG+CNG Q++ G +PG Sbjct: 59 RAG----AIARF-APVMDEVVAAADRGMPV-LGICNGFQVLCEAGLLPGA---------- 102 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 T N F CR + + + + + E + L + GEGR P+ VL Sbjct: 103 ------LTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAPE-KVL 155 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ RY D N NGS IA +CS NGR + LMPHPE + Sbjct: 156 DELEGEGRVVFRYHD-----------NVNGSLRDIAGICSANGRVVGLMPHPEHA 199
>P65903:PURQ_MYCBO Phosphoribosylformylglycinamidine synthase 1 - Mycobacterium bovis| Length = 224 Score = 62.0 bits (149), Expect = 9e-09 Identities = 63/235 (26%), Positives = 95/235 (40%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++ ++ G+ D + + A G E + +D A L + GGFSY D L Sbjct: 4 RIGVVTFPGTLDDVDAARAARQVGAEVVSLWHAD-----ADLKGVDAVVVPGGFSYGDYL 58 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A RF P++ + +R LG+CNG Q++ G +PG Sbjct: 59 RAG----AIARF-APVMDEVVAAADRGMPV-LGICNGFQVLCEAGLLPGA---------- 102 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 T N F CR + + + + + E + L + GEGR P+ VL Sbjct: 103 ------LTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAPE-KVL 155 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ RY D N NGS IA +CS NGR + LMPHPE + Sbjct: 156 DELEGEGRVVFRYHD-----------NVNGSLRDIAGICSANGRVVGLMPHPEHA 199
>Q92PI1:PURQ_RHIME Phosphoribosylformylglycinamidine synthase 1 - Rhizobium meliloti| (Sinorhizobium meliloti) Length = 223 Score = 61.6 bits (148), Expect = 1e-08 Identities = 59/234 (25%), Positives = 95/234 (40%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAF-HAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 K A+++ G N D +M AA +G P + ++ + + I GGFSY D Sbjct: 2 KSAVVQLPGLNRDCDMIAALTKISGKAPVTVWQTE-----TEIPDVDLIVIPGGFSYGDY 56 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P++Q + + LGVCNG Q++ G +PG Sbjct: 57 LR-----CGAIAARMPVMQAIKAKAEQ-GVRVLGVCNGFQILVEAGLLPGA--------- 101 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNV 1478 N S +F CR + + + ++ + + +G + AH +G +F D Sbjct: 102 -------LMRNASLKFVCREVKLEVVNADTAFTRAYAKGQVIRSPVAHHDGN-YFADAET 153 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 L + + RY + N PNGS IA + + G L +MPHPE Sbjct: 154 LKAIEGNGQVVFRYAEGTN---------PNGSVNDIAGVLNAKGNVLGMMPHPE 198
>Q8FMM2:PURQ_COREF Phosphoribosylformylglycinamidine synthase 1 - Corynebacterium| efficiens Length = 223 Score = 61.6 bits (148), Expect = 1e-08 Identities = 62/238 (26%), Positives = 98/238 (41%), Gaps = 4/238 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFV---GGFSYA 1115 K+ +I G+ D + A AG EP ++ +D + RG+ V GGFSY Sbjct: 4 KIGVITFPGTLDDVDALRAVRIAGAEPVNLWHAD--------EDLRGVDAVVVPGGFSYG 55 Query: 1116 DVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLG 1295 D L + +I P++Q E R LG+CNG Q++ +PG Sbjct: 56 DYLRTG-----AISALAPVMQSVIEAAGRGMPV-LGICNGFQILTEARLLPGA------- 102 Query: 1296 AGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDG 1472 T N+ F C + + ++ + +E G + + + HGEGR Sbjct: 103 ---------LTRNQGLHFHCVDTHLEVVNTDTAWTGTLEQGQKILVPAKHGEGR------ 147 Query: 1473 NVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ +R ++ V Y N NGS GIA + + GR + LMPHPE + Sbjct: 148 ------FQAEPDTIRMLEEEGRVVFRYTDNFNGSINGIAGITNETGRVVGLMPHPEHA 199
>Q2ITP9:PURQ_RHOP2 Phosphoribosylformylglycinamidine synthase 1 - Rhodopseudomonas| palustris (strain HaA2) Length = 233 Score = 61.2 bits (147), Expect = 2e-08 Identities = 60/234 (25%), Positives = 98/234 (41%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFH-AAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 K A++ G N +R+M+ A +G + + +D + + T+ + GGFSY D Sbjct: 2 KSAVLVFPGINRERDMARALKLVSGHDAAMVWHAD--TELPNGTDL--VVVPGGFSYGDY 57 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P++ ++F + LGVCNG Q++ G +PG Sbjct: 58 LR-----CGAIAARAPVMDAVRKFAS-DGGLVLGVCNGFQILCESGLLPGV--------- 102 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNV 1478 N +F CR + + + + S +G G + + AHGEG + D Sbjct: 103 -------LMRNARLKFICRDVHLRVERNDSPFTRGYAAGQVIKVPVAHGEGN-YEADEET 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 + + RYC + E + N NG+ IA + S G L +MPHPE Sbjct: 155 VKRLEGDGRVLYRYCSPEGEIGESH--NINGAAASIAGIVSERGNVLGMMPHPE 206
>Q6N376:PURQ_RHOPA Phosphoribosylformylglycinamidine synthase 1 - Rhodopseudomonas| palustris Length = 233 Score = 60.5 bits (145), Expect = 3e-08 Identities = 61/234 (26%), Positives = 97/234 (41%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFV-GGFSYADV 1121 K A++ G N +R+M+ A D M + + + L + + V GGFSY D Sbjct: 2 KSAVLVFPGINRERDMARALKLVSGN--DAAM--VWHAETELPKGTDLVVVPGGFSYGDY 57 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P++ ++F LGVCNG Q++ G +PG Sbjct: 58 LR-----CGAIAARAPVMDAVRKFA-ADGGLVLGVCNGFQILCESGLLPGV--------- 102 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNV 1478 N +F CR + + + + + +G + G + + AHGEG + D + Sbjct: 103 -------LMRNARLKFICRDVHLRVERNDTPFTQGYKAGQVIKVPVAHGEGN-YEADEDT 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 + + RYC V E + N NG+ IA + S G L +MPHPE Sbjct: 155 VKRLEGDGRVLYRYCSPEGEVGESH--NINGAAASIAGIVSERGNVLGMMPHPE 206
>Q1QMU3:PURQ_NITHX Phosphoribosylformylglycinamidine synthase 1 - Nitrobacter| hamburgensis (strain X14 / DSM 10229) Length = 233 Score = 60.1 bits (144), Expect = 3e-08 Identities = 59/234 (25%), Positives = 94/234 (40%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHA-AGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADV 1121 K AI+ G N +R+M+ A +G EP + ++ K + + GGFSY D Sbjct: 2 KSAILVFPGINRERDMARALKLISGHEPAMVWHAETSLPKGTDL----VVMPGGFSYGDY 57 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L +I P++ + F LGVCNG Q++ G +PG Sbjct: 58 LR-----CGAIAARSPVMDAVRAFA-ADGGLVLGVCNGFQILCESGLLPGI--------- 102 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNV 1478 N +F C + + + S + +G G + + AHGEG + D Sbjct: 103 -------LMRNARLKFICHDVHLRVERSDTPFTRGYNAGQVIRVPVAHGEGN-YAADEET 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 + + RYC + + + N NG+ IA + + G L +MPHPE Sbjct: 155 IRRLEGEGRVLYRYCSATGEIGDTH--NINGAAQSIAGIVNVRGNVLGMMPHPE 206
>Q8F0I2:PURQ_LEPIN Phosphoribosylformylglycinamidine synthase 1 - Leptospira interrogans| Length = 219 Score = 59.3 bits (142), Expect = 6e-08 Identities = 62/239 (25%), Positives = 105/239 (43%), Gaps = 5/239 (2%) Frame = +3 Query: 945 KVAIIREEGSNSD----REMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSY 1112 K+A+I GSN D R + ++A W D L++K L + GGFSY Sbjct: 2 KIAVITFPGSNCDSDIYRVLKDQYNAEVDRIWH---RDGLDKKYEL-----VILPGGFSY 53 Query: 1113 ADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSL 1292 D L S A F+ P+++ +E ++ G+CNG Q++ ++PG I Sbjct: 54 GDYLRSG----AMAGFS-PVMKSVKEHVDKGGKL-FGICNGFQILTEAEYLPGALI---- 103 Query: 1293 GAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPD 1469 N++ ++ C+ + + G + + + M+ L I AH +G ++ Sbjct: 104 ------------RNKTLKYICKTVILTKGSAGNPVTASMDVRKELKIPIAHADG-CYYAT 150 Query: 1470 GNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +VL + + RY + NPNGS IA + S N + + +MPHPER+ Sbjct: 151 SDVLKQLEDEDRILFRYSGE----------NPNGSLDSIAGITSKNFKIVGMMPHPERA 199
>Q72UH6:PURQ_LEPIC Phosphoribosylformylglycinamidine synthase 1 - Leptospira interrogans| serogroup Icterohaemorrhagiae serovar copenhageni Length = 219 Score = 59.3 bits (142), Expect = 6e-08 Identities = 62/239 (25%), Positives = 105/239 (43%), Gaps = 5/239 (2%) Frame = +3 Query: 945 KVAIIREEGSNSD----REMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSY 1112 K+A+I GSN D R + ++A W D L++K L + GGFSY Sbjct: 2 KIAVITFPGSNCDSDIYRVLKDQYNAEVDRIWH---RDGLDKKYEL-----VILPGGFSY 53 Query: 1113 ADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSL 1292 D L S A F+ P+++ +E ++ G+CNG Q++ ++PG I Sbjct: 54 GDYLRSG----AMAGFS-PVMKSVKEHVDKGGKL-FGICNGFQILTEAEYLPGALI---- 103 Query: 1293 GAGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPD 1469 N++ ++ C+ + + G + + + M+ L I AH +G ++ Sbjct: 104 ------------RNKTLKYICKTVILTKGSAGNPVTASMDVRKELKIPIAHADG-CYYAT 150 Query: 1470 GNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +VL + + RY + NPNGS IA + S N + + +MPHPER+ Sbjct: 151 SDVLKQLEDEDRILFRYSGE----------NPNGSLDSIAGITSKNFKIVGMMPHPERA 199
>Q5FNL1:PURQ_GLUOX Phosphoribosylformylglycinamidine synthase 1 - Gluconobacter oxydans| (Gluconobacter suboxydans) Length = 233 Score = 59.3 bits (142), Expect = 6e-08 Identities = 60/234 (25%), Positives = 95/234 (40%), Gaps = 2/234 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K AI+ G+N +R+M A + + + + + SL + + GGFS+ D L Sbjct: 2 KAAIVVFPGTNRERDMVHALKLVTGQAPRL----IWHGETSLGDLDLVVLPGGFSFGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 S ++ + P+++ + F + LGVCNG Q++ +PG Sbjct: 58 RSG-----AVAAHSPIMRDVKAFAGKGGHV-LGVCNGFQILTESHLLPGA---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGM-EGSTLGIWSAHGEGRAFFPDGNVL 1481 N RF + + + ++ S +G G AHG+G + L Sbjct: 102 ------LLRNAGLRFLSQDCHLKVENASSPYTQGWTRGDVFRAPLAHGDGN-YTASPETL 154 Query: 1482 SDVVKSNLAPLRYCDDANNVTEV-YPFNPNGSPLGIAALCSPNGRHLALMPHPE 1640 + RYC V++ NPNGS IA + S NGR LMPHPE Sbjct: 155 KRLEGEGRVAFRYCGADGAVSDDDRTTNPNGSTRSIAGILSENGRVCGLMPHPE 208
>Q6N9F2:PURL_RHOPA Phosphoribosylformylglycinamidine synthase II - Rhodopseudomonas| palustris Length = 736 Score = 59.3 bits (142), Expect = 6e-08 Identities = 56/175 (32%), Positives = 81/175 (46%), Gaps = 1/175 (0%) Frame = +3 Query: 264 DITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFE 443 D T + T K + +LL + + K LG S + P D+ K+ + Sbjct: 557 DFTKSATLAFKAEGEAILL---IGETKGWLGQSVYLREICGREEGAPPPVDLAVEKRHGD 613 Query: 444 VVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELG-L 620 VV+ ++ +A HD+SDGGL+V I EMA AGN G +L+ + F E+ Sbjct: 614 VVRGMIHAGTATAVHDVSDGGLLVAIAEMAIAGNIGASLDAPPGETVSHAWWFGEDQARY 673 Query: 621 VIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDLRDL 785 V+ V DL VK KL GV IG VT ++ ++G ERT DL+ L Sbjct: 674 VVTVKEADLLAVKTKLKTIGVPCTQIG-VTGGHALK--IEG-----ERTVDLKAL 720
>Q9RHW9:PURL_CORAM Phosphoribosylformylglycinamidine synthase II - Corynebacterium| ammoniagenes (Brevibacterium ammoniagenes) Length = 758 Score = 59.3 bits (142), Expect = 6e-08 Identities = 36/109 (33%), Positives = 57/109 (52%), Gaps = 1/109 (0%) Frame = +3 Query: 474 ISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELG-LVIEVHLDDLD 650 ++A HD+S+GGL + EMA N GV+L++ + D L LF+E ++I D LD Sbjct: 639 VAASHDLSEGGLAIAAFEMAQKNNVGVDLDLSVVHEDALTALFSESASRVLISTASDHLD 698 Query: 651 VVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEET 797 + Q+ G+ A V+G + I GE + T++LR+ W T Sbjct: 699 GILQRASELGIPAVVVGTTNDSGNITFA--GE---EVATAELREAWSAT 742
>Q5NMA4:PURQ_ZYMMO Phosphoribosylformylglycinamidine synthase 1 - Zymomonas mobilis| Length = 221 Score = 58.9 bits (141), Expect = 8e-08 Identities = 66/236 (27%), Positives = 98/236 (41%), Gaps = 3/236 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHA-AGFEPWDITMSDLLNQKASLTEFRG-IAFVGGFSYAD 1118 K A++ GSN DR+++ A G +P + +Q++ L + IA GGFSY D Sbjct: 2 KAAVLVFPGSNCDRDLAVAIEKICGTKPLMVW-----HQESELPDDLDLIAVPGGFSYGD 56 Query: 1119 VLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGA 1298 L S AA +I+Q + LG+CNG Q++ G +PG Sbjct: 57 YLRSG-AMAARSAVMPAVIKQAER-----GVPVLGICNGFQILTEAGLLPGA-------- 102 Query: 1299 GGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFK-GMEGSTLGIWSAHGEGRAFFPDGN 1475 N F CR + + I ++ S + + + + AH DGN Sbjct: 103 --------LMRNAGLSFICRNVGLEIQNTTSPFLRLYKKNQKIHLPVAHH-------DGN 147 Query: 1476 VLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPER 1643 +D A L +D + V Y + NGS IA + + G L LMPHPER Sbjct: 148 YTADE-----ATLDQLEDEDRVALRYTESVNGSARNIAGVLNKKGNVLGLMPHPER 198
>Q6A6B0:PURQ_PROAC Phosphoribosylformylglycinamidine synthase 1 - Propionibacterium| acnes Length = 224 Score = 58.9 bits (141), Expect = 8e-08 Identities = 59/235 (25%), Positives = 92/235 (39%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++ ++ G+ D++ + A AG EP + + L + GGFSY D L Sbjct: 3 RIGVVTFPGTLDDQDAARAVRLAGAEPVSLWYAS-----TDLAGVDAVILPGGFSYGDYL 57 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + AAS P++ + + LG+CNG Q++ +PG Sbjct: 58 RAGALAAAS-----PVMSSIRRAADGGLPV-LGICNGFQVLCESHLLPGT---------- 101 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGST-LGIWSAHGEGRAFFPDGNVL 1481 NE RF C + + ++ S + I + HGEG N + Sbjct: 102 ------LMRNEKRRFHCSVQQLQVASVDTVWTCDFRPSERIHIAAKHGEG-------NYV 148 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 +D A + + N V Y NPNGS IA + + G + LMPHPE S Sbjct: 149 ADA-----ATVAALEANNRVVFRYTANPNGSVHDIAGITNEAGNVVGLMPHPEHS 198
>Q6ACD4:PURQ_LEIXX Phosphoribosylformylglycinamidine synthase 1 - Leifsonia xyli subsp.| xyli Length = 232 Score = 58.5 bits (140), Expect = 1e-07 Identities = 64/235 (27%), Positives = 93/235 (39%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++ +I GS DR+ A AG EP + D L + GGFSY D L Sbjct: 2 RIGVITFPGSLDDRDALRAIRLAGAEPVALWHGD-----HDLQGVDALVLPGGFSYGDYL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 G AS+ P++ + E + LG+CNG Q++A VPG I Sbjct: 57 RC--GAIASL---SPIMSEVVEAAGKGMPV-LGICNGFQMLAEAILVPGGLI-------- 102 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 N+ G F C + + ++ + G E G + I +GEG +F L Sbjct: 103 --------RNDHGNFICHAQRLTVENAETPWTGGFERGQKIVIPLKNGEG-SFIASAEEL 153 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + RY NPNGS IA + + G + LMPHPE + Sbjct: 154 KRLEGEGMVVFRYRG----------VNPNGSLNDIAGVRNERGNVVGLMPHPEHA 198
>Q5FIV1:PURL_LACAC Phosphoribosylformylglycinamidine synthase II - Lactobacillus| acidophilus Length = 742 Score = 58.5 bits (140), Expect = 1e-07 Identities = 36/132 (27%), Positives = 75/132 (56%), Gaps = 1/132 (0%) Frame = +3 Query: 402 PDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDN 581 P ++P +K +Q+L++E L+ + HD+S+GGL V++ E F + GVN+ ++ N Sbjct: 609 PHAPNLPGIKDYLYKLQKLMAEGLVQSAHDLSEGGLGVSLAESVFDTDLGVNVKLDFNKN 668 Query: 582 DLLQTLFAEELG-LVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLK 758 LF+E G L++ V ++ +Q++ G + + IG+VT ++ + + + ++ Sbjct: 669 ----LLFSETPGRLIVSVAPENAAKFEQEM---GDAVSEIGQVTDDKQLNISLTND-QVN 720 Query: 759 ERTSDLRDLWEE 794 E + L+ +W+E Sbjct: 721 EDVAKLQKIWKE 732
>Q7VFQ4:PURQ_HELHP Phosphoribosylformylglycinamidine synthase 1 - Helicobacter hepaticus| Length = 222 Score = 58.2 bits (139), Expect = 1e-07 Identities = 59/234 (25%), Positives = 95/234 (40%), Gaps = 1/234 (0%) Frame = +3 Query: 948 VAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVLD 1127 VAI+R G+N + + AF G + + D K+ T+ + GGFSY D L Sbjct: 3 VAIVRFPGTNCEFDTQYAFSLFGGVTYIVWHQD----KSLPTDCHLVVIPGGFSYGDYLR 58 Query: 1128 SAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGGD 1307 +I P+++ ++F + + LG+CNG Q++ G +PG Sbjct: 59 -----CGAIAQFSPIMRVIKDFALQGG-YVLGICNGFQILCEAGLLPG------------ 100 Query: 1308 MSQPRFTHNESGRFECRFISVAIGDSPSIMFKG-MEGSTLGIWSAHGEGRAFFPDGNVLS 1484 N + F + S+ I + + + + AH +G +F D L Sbjct: 101 ----ALKRNINLHFISQMQSLRIVSKNNAFLRSYAPNQEIRLPIAHADGN-YFIDERELL 155 Query: 1485 DVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ + L Y D NPNGS IA +C+ LMPHPER+ Sbjct: 156 ELRANEQILLEYTD-----------NPNGSVDSIAGICNEKKNVFGLMPHPERA 198
>Q8NMI4:PURQ_CORGL Phosphoribosylformylglycinamidine synthase 1 - Corynebacterium| glutamicum (Brevibacterium flavum) Length = 223 Score = 58.2 bits (139), Expect = 1e-07 Identities = 60/235 (25%), Positives = 93/235 (39%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 K+ +I G+ D + + A AG E + +D L + GGFSY D L Sbjct: 4 KIGVITFPGTLDDVDAARAARIAGAEVISLWHAD-----EDLKGVDAVVVPGGFSYGDYL 58 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + +I P++Q E + LG+CNG Q++ +PG Sbjct: 59 RTG-----AISALAPVMQSVIEQAGKGMPV-LGICNGFQILTEARLLPGA---------- 102 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 T N+ F C + + ++ + +E G + I + HGEGR F D + Sbjct: 103 ------LTRNKGLHFHCVDAHLVVENNTTAWTNTLEKGQQILIPAKHGEGR-FQADAETI 155 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + RY D N NGS IA + + GR + LMPHPE + Sbjct: 156 AQLEGEGRVVFRYTD-----------NFNGSVNDIAGITNETGRIVGLMPHPEHA 199
>Q743F9:PURQ_MYCPA Phosphoribosylformylglycinamidine synthase 1 - Mycobacterium| paratuberculosis Length = 224 Score = 57.8 bits (138), Expect = 2e-07 Identities = 62/235 (26%), Positives = 95/235 (40%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++ II G+ D + + A G +P + +D A L + GGFSY D L Sbjct: 4 RIGIITFPGTLDDVDAARAARRVGAQPVSLWHAD-----ADLKGVDAVVVPGGFSYGDYL 58 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A RF P++ + + R LG+CNG Q++ G +PG Sbjct: 59 RAG----AIARF-APVMTEVVDAARRGMPV-LGICNGFQVLCEAGLLPGA---------- 102 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 T N F CR + + + + + E + L + GEGR P +VL Sbjct: 103 ------LTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAP-ADVL 155 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ RY + N NGS IA + S +GR + LMPHPE + Sbjct: 156 DELEGEGRVVFRYHE-----------NLNGSQRDIAGVSSADGRVVGLMPHPEHA 199
>O05756:PURQ_MYCLE Phosphoribosylformylglycinamidine synthase 1 - Mycobacterium leprae| Length = 224 Score = 57.4 bits (137), Expect = 2e-07 Identities = 62/235 (26%), Positives = 93/235 (39%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++ +I G+ D + + A G E + +D A L + GGFSY D L Sbjct: 4 RIGVITFPGTLDDVDAARAARHVGAEAVSLWHAD-----ADLKGVDAVVVPGGFSYGDYL 58 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I P++ + + R LG+CNG Q++ G +PG I Sbjct: 59 R-----AGAIARLSPIMTEVVDAVQRGMPV-LGICNGFQVLCEAGLLPGALI-------- 104 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGST-LGIWSAHGEGRAFFPDGNVL 1481 N F CR + + + + + E T L + GEGR + NVL Sbjct: 105 --------RNVGLHFICRDVWLRVISTSTAWTSRFEPETDLLVSLKSGEGR-YVASENVL 155 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ RY D N NGS IA + S NGR + +MPHPE + Sbjct: 156 DELDGEGRVVFRYHD-----------NINGSLRDIAGISSANGRVVGMMPHPEHA 199
>Q9RKK6:PURQ_STRCO Phosphoribosylformylglycinamidine synthase 1 - Streptomyces| coelicolor Length = 226 Score = 57.0 bits (136), Expect = 3e-07 Identities = 59/235 (25%), Positives = 92/235 (39%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++ ++ GS DR+ A AG EP + D L + + GGFSY D L Sbjct: 4 RIGVVTFPGSLDDRDTQRAIRVAGAEPVALWHKD-----KDLKQVDAVVLCGGFSYGDYL 58 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A RF+ + + + LG+CNG Q++ +PG G LG Sbjct: 59 RAG----AIARFSPVMDTVIDQA--KAGLPVLGICNGFQILTEAHLLPG----GMLG--- 105 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 N+ F CR + + ++ + G + I + +GR + D L Sbjct: 106 ---------NDHLHFICRDQKLRVENADTSWTSDYTAGQEIHIPLKNMDGR-YVADRRTL 155 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 ++ RY D NPNGS IA + + G + LMPHPE + Sbjct: 156 DELEAEGRVAFRYLD----------MNPNGSLNDIAGITNAAGNVVGLMPHPEHA 200
>Q8ZZJ9:PURQ_PYRAE Phosphoribosylformylglycinamidine synthase 1 - Pyrobaculum aerophilum| Length = 212 Score = 57.0 bits (136), Expect = 3e-07 Identities = 63/235 (26%), Positives = 96/235 (40%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++A+++ G+N D ++ A AG + D K + + GGFSY D L Sbjct: 2 RIAVLKFPGTNGDYDVLRALELAGARGELVWYRDYAAGK-----YDAVVLAGGFSYGDRL 56 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 A +I + +E R LG+CNG Q++ G +PG I Sbjct: 57 R-----AGAIAAATKAMDHVREDAERGVPV-LGICNGFQILTEAGLLPGALI-------- 102 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRAFFPDGNVL 1481 N+ F R+++V + D+ + + EG + + AHGEGR + P G Sbjct: 103 --------PNDPPGFISRWVAVRVVDTRTPFTYLYEEGEVVYMPIAHGEGR-YVPAGEY- 152 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 A +Y D NPNGS +A + N L LMPHPER+ Sbjct: 153 -------KAAFKYVD-----------NPNGSYDNVAGVYEKN--VLGLMPHPERA 187
>Q38XW8:PURQ_LACSS Phosphoribosylformylglycinamidine synthase 1 - Lactobacillus sakei| subsp. sakei (strain 23K) Length = 228 Score = 57.0 bits (136), Expect = 3e-07 Identities = 60/243 (24%), Positives = 100/243 (41%), Gaps = 9/243 (3%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKA--------SLTEFRGIAFVG 1100 K A++ GSN D ++ +HA + D+ +++A SL F + G Sbjct: 2 KFAVLVFPGSNCDADL---YHA---------IVDVCHEEAAYVSYTATSLAGFDAVLIPG 49 Query: 1101 GFSYADVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDI 1280 GFSY D L S +I P++ F LG+CNG Q++ G +PG Sbjct: 50 GFSYDDYLRSG-----AIAKLAPIMTAVVAFAKAGKPV-LGICNGFQILTEAGLLPGA-- 101 Query: 1281 GGSLGAGGDMSQPRFTHNESGRFECRFISVAIGDSPS-IMFKGMEGSTLGIWSAHGEGRA 1457 N F C +++ + ++ + + +G+T+ + AHGEG Sbjct: 102 --------------LLPNRQTHFICETVTLQVENNDTRFTNQYAKGATIALPIAHGEGN- 146 Query: 1458 FFPDGNVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHP 1637 ++ D L+ + ++ Y D N GS IA + + G L +MPHP Sbjct: 147 YYCDPETLAQLHANHQIAFTYTTDVN-----------GSLDNIAGITNEAGNVLGMMPHP 195 Query: 1638 ERS 1646 ER+ Sbjct: 196 ERA 198
>O67691:PURL_AQUAE Phosphoribosylformylglycinamidine synthase II - Aquifex aeolicus| Length = 745 Score = 57.0 bits (136), Expect = 3e-07 Identities = 45/168 (26%), Positives = 79/168 (47%), Gaps = 3/168 (1%) Frame = +3 Query: 294 KLGKDGVLLHV-DLAKGKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSER 470 K+ K+ L V +L + R G L I D P + D+ K + ++ ++ Sbjct: 570 KVEKESELYLVGNLEENLRLDGSEYLKVIHGLIKGDVPPV-DLEKEKILINLLISFNNKE 628 Query: 471 LISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEE--LGLVIEVHLDD 644 LI+ HD+S GGL++ +LEM F G L +E+ ++ F E ++I V D Sbjct: 629 LITCAHDVSVGGLLIALLEMVFRTPYG--LEVEVYTDERPDVFFFSENPTRVIIGVESDK 686 Query: 645 LDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDLRDLW 788 + VK + AG+ IG+ T +I++ +G+ L++ + LW Sbjct: 687 AEEVKNAVEKAGLEWMYIGKTTEEKKIKVTFNGDTLLEDELEEYEKLW 734
>Q9A5F3:PURQ_CAUCR Phosphoribosylformylglycinamidine synthase 1 - Caulobacter crescentus| (Caulobacter vibrioides) Length = 220 Score = 56.6 bits (135), Expect = 4e-07 Identities = 58/237 (24%), Positives = 95/237 (40%), Gaps = 2/237 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRG-IAFVGGFSYADV 1121 K A+I GSN DR+ A + + + +Q+ +L + I GGFSY D Sbjct: 2 KAAVIVFPGSNCDRDCKVAIERSA----GARVEMVWHQETALPDDLDLIVLPGGFSYGDY 57 Query: 1122 LDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAG 1301 L A S P++++ + +G+CNG Q++ +G +PG Sbjct: 58 LRCGAMAAQS-----PVMKEVVSAAGK-GVAVVGICNGFQVLTEVGLLPGA--------- 102 Query: 1302 GDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGMEGSTLGIWSA-HGEGRAFFPDGNV 1478 N ++ C+ + + I + + G + + +GEG +F D Sbjct: 103 -------LLRNAGLKYVCKPVELDIVNGQTRFTAGYGEQRQAVMTVGNGEGN-YFADEET 154 Query: 1479 LSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERSF 1649 L + RY + NPNGS IA + + G L LMPHP+R+F Sbjct: 155 LDRLEGEGQVVFRYKE-----------NPNGSARDIAGIVNKGGNVLGLMPHPDRAF 200
>Q3B3Y0:PURL_PELLD Phosphoribosylformylglycinamidine synthase 2 - Pelodictyon luteolum| (strain DSM 273) (Chlorobium luteolum (strain DSM 273)) Length = 761 Score = 56.6 bits (135), Expect = 4e-07 Identities = 60/207 (28%), Positives = 91/207 (43%), Gaps = 11/207 (5%) Frame = +3 Query: 231 NLVISAYVTCPD-ITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFDQIGNDCPD 407 NLV SA+ T D I L P LKL G + G D PD Sbjct: 573 NLVGSAFTTAGDAIILFGDPLLKLE-----------------GSEFQVMQYGTPGTDAPD 615 Query: 408 IEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNC-GVNLNIELKD-- 578 I D+ + K + +++ L ++L+ + HD+SDGGL VT+ E A + ++L+D Sbjct: 616 I-DLQHEKNLQDLLVTLAEQKLLHSAHDVSDGGLFVTLAEKAIMDESRQLGFQVDLEDCG 674 Query: 579 ---NDLLQTLFAEELGLVI-EVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGE 746 + + LF+E G V+ + D V ++ V VIG+V A + L VDG Sbjct: 675 SGPYRVQEQLFSEAQGRVVGTIAPDAARAVIEEAIRHSVPVRVIGQVVPA-DASLAVDGH 733 Query: 747 VRLKERTSDLRDLWE---ETSFQLEEL 818 L+ T +L + E + L EL Sbjct: 734 ETLRFTTEELTAAYYDALENALHLNEL 760
>Q2RWI3:PURL_RHORT Phosphoribosylformylglycinamidine synthase 2 - Rhodospirillum| rubrum (strain ATCC 11170 / NCIB 8255) Length = 740 Score = 56.2 bits (134), Expect = 5e-07 Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 1/101 (0%) Frame = +3 Query: 402 PDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDN 581 P D+ +KV + V+ L+ ++A HD+SDGGL+V + EMA AG+ G L +E + Sbjct: 608 PPPVDLAAERKVGDFVRGLILGASVTACHDLSDGGLLVALAEMAMAGDLGAELTLEGHPD 667 Query: 582 DLLQTLFAEELG-LVIEVHLDDLDVVKQKLHAAGVSANVIG 701 + LF E+ G ++ V D D V AAGV V+G Sbjct: 668 N--GRLFGEDQGRYLLTVAEGDRDAVVAAAEAAGVPLRVVG 706
>Q8UEB0:PURL_AGRT5 Phosphoribosylformylglycinamidine synthase II - Agrobacterium| tumefaciens (strain C58 / ATCC 33970) Length = 775 Score = 56.2 bits (134), Expect = 5e-07 Identities = 37/111 (33%), Positives = 56/111 (50%) Frame = +3 Query: 429 KKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE 608 KK + V+ L++E L +A HD S GGL + + EMA + G ++ N +L + Sbjct: 644 KKNGDFVRGLITEGLTTAVHDCSSGGLALAVAEMAISSGIGATIDAVEGHNPILTFYGED 703 Query: 609 ELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKE 761 + V+ V DLD V+ AAGVS +IG T ++L V +KE Sbjct: 704 QARYVLTVKKSDLDKVRAAAKAAGVSCPLIG-TTGGSTVKLGTARAVEIKE 753
>Q8RBK5:PURL_THETN Phosphoribosylformylglycinamidine synthase II - Thermoanaerobacter| tengcongensis Length = 733 Score = 55.5 bits (132), Expect = 8e-07 Identities = 45/176 (25%), Positives = 84/176 (47%), Gaps = 1/176 (0%) Frame = +3 Query: 264 DITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSA-LAQAFDQIGNDCPDIEDVPYLKKVF 440 D++ T D K +D +++ L + K +G S L F + P I D+ K++ Sbjct: 552 DVSKICTMDFKKERDVIII---LGENKGEIGGSEYLKVCFGMVKGQPPQI-DLEKEKRLQ 607 Query: 441 EVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGL 620 E+V +L+ E LI++ HDIS+GG ++E A AG G ++++ ++ + Sbjct: 608 ELVLKLIDEGLINSSHDISEGGFAAALVESAIAGKKGAKISLQTSLRADIELFSESQSRA 667 Query: 621 VIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDLRDLW 788 +I V + +D V + + V A +G V +I + V+G+ + L + W Sbjct: 668 LITVSPEKVDEVLKIAYEHQVPAQKVG-VVEGKDIVIDVNGKRIIDLPLEVLEESW 722
>Q9RHX0:PURQ_CORAM Phosphoribosylformylglycinamidine synthase 1 - Corynebacterium| ammoniagenes (Brevibacterium ammoniagenes) Length = 225 Score = 55.1 bits (131), Expect = 1e-06 Identities = 61/238 (25%), Positives = 94/238 (39%), Gaps = 4/238 (1%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFV---GGFSYA 1115 K+ +I G+ D + A AG E + +D T+ +G+ V GGFSY Sbjct: 4 KIGVITFPGTLDDVDAQRAVRLAGAEAVSLWHAD--------TDLKGVDAVVVPGGFSYG 55 Query: 1116 DVLDSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLG 1295 D L S +I P++Q + R +LG+CNG Q++ G + G Sbjct: 56 DYLRSG-----AISALAPVMQSVVD-RARQGMPTLGICNGFQILTEAGLLEGA------- 102 Query: 1296 AGGDMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDG 1472 T N+ F C + + ++ + E G + + + HGEGR F Sbjct: 103 ---------LTRNKGLHFHCVDTHLEVVNNNTAWTTEFEAGDKIFVPAKHGEGR-FQAAP 152 Query: 1473 NVLSDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + + RY D N NGS IA + + GR + LMPHPE + Sbjct: 153 ETIDKLEGEGQVVFRYTD-----------NFNGSLNDIAGITNETGRIVGLMPHPEHA 199
>Q6KZR2:PURL_PICTO Phosphoribosylformylglycinamidine synthase II - Picrophilus| torridus Length = 741 Score = 54.7 bits (130), Expect = 1e-06 Identities = 39/124 (31%), Positives = 66/124 (53%), Gaps = 2/124 (1%) Frame = +3 Query: 426 LKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFA 605 L V+ +++E ++ I A HD+SDGG+I ++EM+F N G N+N++ +L LF+ Sbjct: 623 LCNVYNIIKE--NKEKILAAHDVSDGGIIAALIEMSFGKNIGFNVNLKDIKMNLENKLFS 680 Query: 606 EE-LGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGE-VRLKERTSDLR 779 E +VIEV L+ V G + + I ++DGE + R S+L+ Sbjct: 681 EHGTAIVIEVPLESEIVFNNLGIKLGYTCDDI----------TVMDGENMVFNARISELK 730 Query: 780 DLWE 791 +LW+ Sbjct: 731 NLWD 734 Score = 39.7 bits (91), Expect = 0.047 Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 6/127 (4%) Frame = +3 Query: 384 QIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLN 563 Q+GN P +E+ + + EL LI+ D+ GGL + EM +AGN G +N Sbjct: 251 QLGN--PIVEE-----PLIHAILELNDLGLITGMKDLGGGGLSSAVTEMLYAGNLGGTIN 303 Query: 564 IE---LKDNDLLQ---TLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEI 725 ++ LKD+++L + + ++I +L +K L + +VIG + Sbjct: 304 LDSVLLKDDNMLPWEIWISESQERMLISSDERNLPQIKDVLDKWNIEFSVIGRAEEKKNL 363 Query: 726 ELLVDGE 746 E+ E Sbjct: 364 EIYYKNE 370
>Q98NN7:PURL_RHILO Phosphoribosylformylglycinamidine synthase II - Rhizobium loti| (Mesorhizobium loti) Length = 743 Score = 54.3 bits (129), Expect = 2e-06 Identities = 33/105 (31%), Positives = 56/105 (53%), Gaps = 5/105 (4%) Frame = +3 Query: 402 PDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDN 581 P D+ + K+V + V+ L++ +++A HD+SDGG+ V + EMA A G + L Sbjct: 604 PPPVDLAHEKRVGDHVRSLIASGIVTAAHDVSDGGIAVALAEMAMASGIGATVP-GLVGT 662 Query: 582 DLLQTLFAEELG-----LVIEVHLDDLDVVKQKLHAAGVSANVIG 701 D + F E+ G L I+ H D+ D ++++ G+ A IG Sbjct: 663 DPIPVWFGEDQGRYLLTLSIDPHGDEWDAIRKQQGELGIFAPWIG 707
>Q67KF8:PURL_SYMTH Phosphoribosylformylglycinamidine synthase II - Symbiobacterium| thermophilum Length = 778 Score = 53.9 bits (128), Expect = 2e-06 Identities = 55/208 (26%), Positives = 99/208 (47%), Gaps = 6/208 (2%) Frame = +3 Query: 150 LGIAIDGGKDSLSMAAQCDGELVKAPGNL-VISAYVTCPDITLTVTPDLKLGKDGVLLHV 326 LG + GG ++S + GE + + +I+ + +T TP K D +LL Sbjct: 548 LGTPVTGG--NVSFYNETSGEAIHPTPTIGMIAVHENLDRLT---TPGFKQVGDVILL-- 600 Query: 327 DLAKGKRRLGCSALAQAFDQI-GNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDG 503 L + + LG S A+ + D P + D+ + K++ +VV + E L++A HD+++G Sbjct: 601 -LGETRDELGGSEYARLIHGVLAGDAPAL-DLAFEKRLQDVVLRAIHEGLVTAAHDVAEG 658 Query: 504 GLIVTILEMAFAG---NCGVNLNIELKDNDLLQTLFAE-ELGLVIEVHLDDLDVVKQKLH 671 GL V + EMA A + G ++I L + + LF E + +++ + + ++ L Sbjct: 659 GLAVALAEMAIAAAEPSLGCQVSIFLGEGRVDGQLFGESQSRILVTATREQVGRLQALLM 718 Query: 672 AAGVSANVIGEVTAAPEIELLVDGEVRL 755 + V+G+VTA DG RL Sbjct: 719 VEQIPFRVLGDVTA--------DGRFRL 738
>Q82FW3:PURQ_STRAW Phosphoribosylformylglycinamidine synthase 1 - Streptomyces| avermitilis Length = 234 Score = 53.5 bits (127), Expect = 3e-06 Identities = 60/235 (25%), Positives = 94/235 (40%), Gaps = 1/235 (0%) Frame = +3 Query: 945 KVAIIREEGSNSDREMSAAFHAAGFEPWDITMSDLLNQKASLTEFRGIAFVGGFSYADVL 1124 ++ ++ GS DR+ A AG EP + D L + + GGFSY D L Sbjct: 4 RIGVVTFPGSLDDRDTQRAIKLAGAEPVALWHKD-----KDLKQVDAVVLPGGFSYGDYL 58 Query: 1125 DSAKGWAASIRFNQPLIQQFQEFYNRPDTFSLGVCNGCQLMALLGWVPGPDIGGSLGAGG 1304 + A RF+ P+++ E + LG+CNG Q++ +PG +G Sbjct: 59 RAG----AISRFS-PVMETVIE-QAKSGMPVLGICNGFQILTEAHLLPGAMLG------- 105 Query: 1305 DMSQPRFTHNESGRFECRFISVAIGDSPSIMFKGME-GSTLGIWSAHGEGRAFFPDGNVL 1481 N F CR + + ++ + E G + I + +GR + D L Sbjct: 106 ---------NNHLHFICRDQKLRVENADTAWTSDYEAGQEIHIPLKNMDGR-YVADERTL 155 Query: 1482 SDVVKSNLAPLRYCDDANNVTEVYPFNPNGSPLGIAALCSPNGRHLALMPHPERS 1646 + RY + Y NPNGS IA + + G + LMPHPE + Sbjct: 156 DMLEAEGRVAFRYVV-GGAAADGYG-NPNGSLRDIAGITNEAGNVVGLMPHPEHA 208
>Q7VEK9:PURL_PROMA Phosphoribosylformylglycinamidine synthase II - Prochlorococcus| marinus Length = 793 Score = 53.1 bits (126), Expect = 4e-06 Identities = 33/110 (30%), Positives = 59/110 (53%), Gaps = 7/110 (6%) Frame = +3 Query: 402 PDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDN 581 P + D+ + K V ++E ++ LI + HDISDGGL++ + E + G+ N+ DN Sbjct: 644 PPLIDLEFEKLVQLFLRESIANNLIKSAHDISDGGLVIGLAESCISSGLGIECNLPEIDN 703 Query: 582 DLLQTLFAE-ELGLVIEVHLDDLDVVKQKL------HAAGVSANVIGEVT 710 L + LFAE +++ V +++ +K L ++ +S N +G VT Sbjct: 704 RLDKLLFAEGGSRVLVSVSPNNIHNIKNSLNNFNIANSEQISFNYLGTVT 753
>Q9KH12:PURL_RHIFR Phosphoribosylformylglycinamidine synthase II - Rhizobium fredii| (Sinorhizobium fredii) Length = 743 Score = 52.8 bits (125), Expect = 5e-06 Identities = 36/129 (27%), Positives = 61/129 (47%), Gaps = 1/129 (0%) Frame = +3 Query: 414 DVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQ 593 D+ + +KV + V+ L+++ L++A HD S GGL + + EMA A G + +D + Sbjct: 608 DLAHERKVGDFVRGLIADGLVTAVHDCSSGGLALAVAEMAMASGIGATIEAP-AGHDPIA 666 Query: 594 TLFAEELG-LVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTS 770 + E+ G V+ V + L+ + + AG+S VIG T L D + E Sbjct: 667 AFYGEDQGRYVVTVTAEKLEAIASRARDAGLSLPVIG--TTGGSAVKLGDAKAVSVEELR 724 Query: 771 DLRDLWEET 797 + W T Sbjct: 725 STHEAWFPT 733
>Q8KD17:PURL_CHLTE Phosphoribosylformylglycinamidine synthase II - Chlorobium tepidum| Length = 759 Score = 52.8 bits (125), Expect = 5e-06 Identities = 49/166 (29%), Positives = 81/166 (48%), Gaps = 11/166 (6%) Frame = +3 Query: 354 GCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMA 533 G L + G D P + D+ + K + E++ L S++LI++ HD+SDGGL VT+ E + Sbjct: 597 GSEYLVMQYGTPGTDSPAV-DLNHEKNLQELLVTLASKKLINSAHDVSDGGLAVTLAEKS 655 Query: 534 FAG-----NCGVNLNIELKDNDLLQ-TLFAEELG-LVIEVHLDDLDVVKQKLHAAGVSAN 692 V+L K+ +Q LF+E G +VI V + V ++ + Sbjct: 656 IMNRERMLGFEVDLECSCKEGTAIQKQLFSEAQGRVVISVDPGRVGAVIEEADRLNIPGR 715 Query: 693 VIGEVTAAPE-IELLVDGEVRLKERTSDLRDLWE---ETSFQLEEL 818 VIG+VT PE + V+G+ + +L + E++ LEEL Sbjct: 716 VIGKVT--PEGASIAVNGKPVAEFMIDELLHAYGHALESALHLEEL 759
>Q92PH7:PURL_RHIME Phosphoribosylformylglycinamidine synthase II - Rhizobium meliloti| (Sinorhizobium meliloti) Length = 743 Score = 51.6 bits (122), Expect = 1e-05 Identities = 31/97 (31%), Positives = 53/97 (54%), Gaps = 1/97 (1%) Frame = +3 Query: 414 DVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQ 593 D+ + +KV + V+ L+ + L++A HD S GGL + + EMA A G ++ ++D + Sbjct: 608 DLGHERKVGDFVRGLIEDGLVTAVHDCSSGGLALAVAEMAIASGIGATIDAP-AEHDPIP 666 Query: 594 TLFAEELG-LVIEVHLDDLDVVKQKLHAAGVSANVIG 701 + E+ G V+ V + V + AAGV+ VIG Sbjct: 667 VFYGEDQGRYVVTVAEGSAETVAARAKAAGVALPVIG 703
>Q9CFE8:PURL_LACLA Phosphoribosylformylglycinamidine synthase II - Lactococcus lactis| subsp. lactis (Streptococcus lactis) Length = 739 Score = 51.2 bits (121), Expect = 2e-05 Identities = 27/98 (27%), Positives = 58/98 (59%), Gaps = 1/98 (1%) Frame = +3 Query: 441 EVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELG- 617 + V + +++ L+S+ HD+++GGL + + E AFA GV++ +++ + LF+E G Sbjct: 623 DFVLKAITDGLVSSAHDLAEGGLAIALAESAFANGLGVDVKVDITN----AQLFSETQGR 678 Query: 618 LVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIEL 731 ++ + ++ ++ L + VS VIG+VT + +E+ Sbjct: 679 FILSISPENQATFEKLLTESSVSGEVIGKVTDSGILEM 716
>Q9A5F0:PURL_CAUCR Phosphoribosylformylglycinamidine synthase II - Caulobacter| crescentus (Caulobacter vibrioides) Length = 739 Score = 50.8 bits (120), Expect = 2e-05 Identities = 33/100 (33%), Positives = 50/100 (50%) Frame = +3 Query: 402 PDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDN 581 P D+ +K + V+ L+S L++ HD+SDGGL+V ++A A GV LN + + Sbjct: 605 PPPVDLALERKTGDFVRGLISSGLVAGVHDLSDGGLLVAAADVALASKIGVTLNATSQTH 664 Query: 582 DLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIG 701 L ++ +I D D V + AGV ANV G Sbjct: 665 AHAYLLGEDQARYLIAT--PDPDAVLEAAKEAGVHANVAG 702
>Q743F0:PURL_MYCPA Phosphoribosylformylglycinamidine synthase II - Mycobacterium| paratuberculosis Length = 765 Score = 50.4 bits (119), Expect = 3e-05 Identities = 38/119 (31%), Positives = 63/119 (52%), Gaps = 2/119 (1%) Frame = +3 Query: 381 DQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNL 560 D +G P + D+ K + EV++ + L+SA HD+S+GGL ++E A AG G + Sbjct: 625 DHLGGLPPKV-DLAREKLLAEVLRAASRDGLVSAAHDLSEGGLAQAVVEAALAGETGCRI 683 Query: 561 NIELKDNDLLQTLFAEELG-LVIEVHLDDLDVVKQKLHAAGVSANVIGEV-TAAPEIEL 731 + +D D TLF+E G +++ V + + A G+ A IG V A+ E+E+ Sbjct: 684 VLP-EDADPFVTLFSESAGRVLVAVPRTEESRFRSMCEARGLPAVRIGVVDQASDEVEV 741
>Q9ZB06:PURL_LACLC Phosphoribosylformylglycinamidine synthase II - Lactococcus lactis| subsp. cremoris (Streptococcus cremoris) Length = 739 Score = 50.4 bits (119), Expect = 3e-05 Identities = 27/91 (29%), Positives = 54/91 (59%), Gaps = 1/91 (1%) Frame = +3 Query: 441 EVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELG- 617 + V + +++ LI++ HD+S+GGL + + E AFA G+++ ++L + LF+E G Sbjct: 623 DFVLKAITDGLINSAHDLSEGGLAIALAESAFANGLGIDVEVDLSN----AQLFSETQGR 678 Query: 618 LVIEVHLDDLDVVKQKLHAAGVSANVIGEVT 710 V+ + ++ ++ L + S+ VIG+VT Sbjct: 679 FVLSISPENQAAFEKLLTESSASSEVIGKVT 709
>P35852:PURL_LACCA Phosphoribosylformylglycinamidine synthase II - Lactobacillus casei| Length = 740 Score = 49.7 bits (117), Expect = 5e-05 Identities = 32/95 (33%), Positives = 46/95 (48%) Frame = +3 Query: 447 VQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVI 626 V + + E LI+A HD+SDGGL+V + EM F G +N+ L F+E G + Sbjct: 623 VLKAIREHLITAAHDLSDGGLLVALAEMGFDAQLGAQINVTLP----TAWGFSETQGRFL 678 Query: 627 EVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIEL 731 + + LH A +IG V A PE E+ Sbjct: 679 LTVSPENQAAFEALHG---PAQLIGRVQAPPEFEV 710
>Q9RKK5:PURL_STRCO Phosphoribosylformylglycinamidine synthase II - Streptomyces| coelicolor Length = 752 Score = 49.3 bits (116), Expect = 6e-05 Identities = 64/220 (29%), Positives = 96/220 (43%), Gaps = 2/220 (0%) Frame = +3 Query: 144 IQLGIAIDGGKDSLSMAAQCDGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLH 323 +QLG + GG SL GE P +V A + D TP + +DG LL+ Sbjct: 541 LQLGTPVTGGNVSLYNQT---GEAAIHPTPVV--AVLGVIDDVARRTP-VAFQEDGQLLY 594 Query: 324 VDLAKGKRRLGCSALAQAF-DQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISD 500 + L + G SA +Q D +G P + D+ + + E++ + +I + HD+SD Sbjct: 595 L-LGDTREEFGGSAWSQVIHDHLGGLPPKV-DLERERLLGEILISASRDGMIDSAHDLSD 652 Query: 501 GGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELG-LVIEVHLDDLDVVKQKLHAA 677 GGL+ ++E A G G L + D LF+E G V+ V + A Sbjct: 653 GGLVQAVVESALLGGKGARLVVP-DGLDAFTFLFSESAGRAVVAVPRSEEVRFNDMCGAR 711 Query: 678 GVSANVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEET 797 G+ IG V +E V GE L +DLR+ E T Sbjct: 712 GLPVTRIG-VVDGDAVE--VQGEFTLP--LTDLREAHEST 746 Score = 33.5 bits (75), Expect = 3.4 Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 8/113 (7%) Frame = +3 Query: 429 KKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIE--------LKDND 584 K + E E +E+L+ D+ GL E+A G+ G+ + ++ L + Sbjct: 261 KLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSGGMRVTLDDVPLRDSTLSPEE 320 Query: 585 LLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDG 743 +L + E + V+E + +D + V A VIGEVT +E+ G Sbjct: 321 ILMSESQERMCAVVEP--EKVDRFLEICDKWDVIATVIGEVTDGDRLEIFWHG 371
>Q58660:PURL_METJA Phosphoribosylformylglycinamidine synthase II - Methanococcus| jannaschii Length = 733 Score = 49.3 bits (116), Expect = 6e-05 Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 4/100 (4%) Frame = +3 Query: 414 DVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNI-ELKDNDLL 590 D+ KK++E V+E++ E L+S D S GGL V + +MA N G+ +++ E N+L Sbjct: 599 DLEKEKKIYEEVREVVKEGLVSEAVDCSRGGLAVALAKMAVLNNIGLEVDLTEYNKNNLR 658 Query: 591 Q--TLFAEELG-LVIEVHLDDLDVVKQKLHAAGVSANVIG 701 LF+E G +++ V ++ D V KL +A + V G Sbjct: 659 DDILLFSETSGRIILAVRDENKDKVLSKLSSAYIIGKVGG 698
>Q2G630:PURL_NOVAD Phosphoribosylformylglycinamidine synthase 2 - Novosphingobium| aromaticivorans (strain DSM 12444) Length = 719 Score = 48.9 bits (115), Expect = 8e-05 Identities = 27/59 (45%), Positives = 38/59 (64%) Frame = +3 Query: 396 DCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIEL 572 D P + D+ ++ E V+E ++ +SA HDISDGGL+V + EMA AGN G L+I L Sbjct: 603 DAPSV-DLAVERRNGEQVREWIAAGRLSAVHDISDGGLLVALTEMALAGNKGCTLDIAL 660
>Q82FW4:PURL_STRAW Phosphoribosylformylglycinamidine synthase II - Streptomyces| avermitilis Length = 752 Score = 48.5 bits (114), Expect = 1e-04 Identities = 65/219 (29%), Positives = 96/219 (43%), Gaps = 2/219 (0%) Frame = +3 Query: 147 QLGIAIDGGKDSLSMAAQCDGELVKAPGNLVISAYVTCPDITLTVTPDLKLGKDGVLLHV 326 QLG + GG SL GE+ P +V A + D TP + ++G LL++ Sbjct: 542 QLGTPVTGGNVSLYNQT---GEVAIHPTPVV--AVLGVIDDVARRTP-VAFQEEGQLLYL 595 Query: 327 DLAKGKRRLGCSALAQAF-DQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDG 503 L + G SA +Q D +G P + D+ + + E++ + +I A HD+SDG Sbjct: 596 -LGDTREEFGGSAWSQVVHDHLGGLPPQV-DLERERLLGEILISASRDGMIDAAHDLSDG 653 Query: 504 GLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELG-LVIEVHLDDLDVVKQKLHAAG 680 GLI ++E A G G L + D LF+E G V+ V + A G Sbjct: 654 GLIQAVVESALLGGKGARLVVP-DGLDAFTFLFSESAGRAVVAVPRSEELRFNDMCGARG 712 Query: 681 VSANVIGEVTAAPEIELLVDGEVRLKERTSDLRDLWEET 797 + IG V +E V GE L ++LR EET Sbjct: 713 LPVTRIG-VVDGDSVE--VQGEFTLP--LAELRKAHEET 746 Score = 32.3 bits (72), Expect = 7.6 Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 9/114 (7%) Frame = +3 Query: 429 KKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIE--------LKDND 584 K + E E +E+L+ D+ GL E+A G+ G+ + ++ L + Sbjct: 261 KLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSGGMRVTLDDVPLRDSTLSPEE 320 Query: 585 LLQTLFAEELGLVIEVH-LDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDG 743 +L + E + V+E +D + +K V A VIGEVT +E+ G Sbjct: 321 ILMSESQERMCAVVEPEKVDRFLAICEKWD---VIATVIGEVTDGDRLEIYWHG 371
>Q3IQL3:PURL_NATPD Phosphoribosylformylglycinamidine synthase 2 - Natronomonas pharaonis| (strain DSM 2160 / ATCC 35678) Length = 713 Score = 48.5 bits (114), Expect = 1e-04 Identities = 53/168 (31%), Positives = 76/168 (45%), Gaps = 1/168 (0%) Frame = +3 Query: 285 PDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFDQIGND-CPDIEDVPYLKKVFEVVQELL 461 P L DG LL V G LG S L F G+D P + D P E V ++ Sbjct: 548 PPAALSGDGDLLVVGDG-GDLELGGSELLAQFG--GSDQFPALPDSP--AAFIEAVADIA 602 Query: 462 SERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVHLD 641 A HD+S GGL V + E+ G+ G ++++ D L LF+E +G V+ V Sbjct: 603 DLDSTHATHDVSHGGLAVALAEL--VGDAGADVDL-AGSPDALSVLFSEAVGRVV-VETT 658 Query: 642 DLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDLRDL 785 D + VK++L IG T + +EL V G+ L +D+ L Sbjct: 659 DPEAVKERLDGV-APVEHIGHATDSGRLELSV-GDETLSYSAADIASL 704 Score = 37.7 bits (86), Expect = 0.18 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 7/104 (6%) Frame = +3 Query: 420 PYL-KKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIEL-----KDN 581 PY K++ E +EL+ + L+ A D+ GL E+ G G ++ ++ + Sbjct: 237 PYAEKRLIEANEELVDDSLVRAARDLGAAGLGGASSELVAKGGLGAHIELDRVHQREPNM 296 Query: 582 DLLQTLFAE-ELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVT 710 + L+ L AE + + EV +D+D V + +VIG+VT Sbjct: 297 NALEILLAESQERMCYEVRPEDVDAVAAVADKYDLGCSVIGDVT 340
>Q50023:PURL_MYCLE Phosphoribosylformylglycinamidine synthase II - Mycobacterium| leprae Length = 754 Score = 48.5 bits (114), Expect = 1e-04 Identities = 33/103 (32%), Positives = 52/103 (50%), Gaps = 1/103 (0%) Frame = +3 Query: 402 PDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDN 581 P + D+ K + EV+ + L+SA HD+S+GGL I+E A AG G + + +D Sbjct: 620 PPMVDLAREKLLAEVLSSASRDELVSAAHDLSEGGLAQAIVESALAGETGCRIALP-EDA 678 Query: 582 DLLQTLFAEELG-LVIEVHLDDLDVVKQKLHAAGVSANVIGEV 707 D LF+E G +++ V + + A G+ A IG V Sbjct: 679 DPFVMLFSESAGRVLVAVPRPEESRFRSMCEARGLPAMRIGVV 721 Score = 32.0 bits (71), Expect = 9.9 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 7/116 (6%) Frame = +3 Query: 420 PYLKKVF-EVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIEL-----KDN 581 P+++KV E EL + L+ D+ GL E+A AG+ G+ + ++ KD Sbjct: 256 PFMEKVLIECCLELYAGGLVIGIQDLGGAGLSCATSELASAGDVGMAIQLDTVPRRAKDM 315 Query: 582 DLLQTLFAE-ELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGE 746 + +E + + V +++D V A VIGEVT + + GE Sbjct: 316 TPAEVFCSESQERMCAVVAPENVDAFLAVCRKWEVLATVIGEVTDGDRLRITWHGE 371
>Q4FLJ4:PURL_PELUB Phosphoribosylformylglycinamidine synthase 2 - Pelagibacter ubique| Length = 730 Score = 48.1 bits (113), Expect = 1e-04 Identities = 47/163 (28%), Positives = 78/163 (47%), Gaps = 4/163 (2%) Frame = +3 Query: 279 VTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQEL 458 VT DLK D +LL + +G L S A+ N P ++ K E + +L Sbjct: 558 VTMDLKEA-DNILLVIGKTEG--HLDQSLFARDILNEKNGPPPEINLFNEKNNGETILKL 614 Query: 459 LSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLL---QTLFAEELG-LVI 626 ++++ I + HD+S GG+I + +M G G L K N L+ + LF E+ G +I Sbjct: 615 INKKFIKSAHDVSLGGIITALSKMCIKGKKGATLK---KSNYLINQFEYLFGEDQGRYII 671 Query: 627 EVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRL 755 E+ DDL+ + L V + +G V E L++D + ++ Sbjct: 672 EISKDDLENATKILQENSVHFDELGLVN---EDGLIIDDKTKV 711
>Q3B100:PURL_SYNS9 Phosphoribosylformylglycinamidine synthase 2 - Synechococcus sp.| (strain CC9902) Length = 766 Score = 47.8 bits (112), Expect = 2e-04 Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 2/103 (1%) Frame = +3 Query: 429 KKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE 608 K+V +V++ +++ LI++ HD SDGGL V + E + A GV L + + + LFAE Sbjct: 636 KRVQGLVRQAIADGLIASAHDSSDGGLAVALAECSIASGFGVELTLSVGTMSPARLLFAE 695 Query: 609 -ELGLVIEVHLDDLDVVKQKLHA-AGVSANVIGEVTAAPEIEL 731 +V+ V D L + L + VS V+G V + +L Sbjct: 696 GGARVVVSVKADQLTRWQTMLTSNPDVSTTVLGTVASHGRFQL 738 Score = 42.0 bits (97), Expect = 0.010 Identities = 51/229 (22%), Positives = 96/229 (41%), Gaps = 32/229 (13%) Frame = +3 Query: 228 GNLVISAYVTCPDITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQA---FDQIGND 398 GN +++A T + +G +++V G+ +G ++ A A D + +D Sbjct: 177 GNPLVNAMALGLMETKDIVKSGAIGVGNPVVYVGSTTGRDGMGGASFASAELSADSL-DD 235 Query: 399 CPDIE-DVPYLKK-VFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIE- 569 P ++ P+L+K + E E + A D+ GL + EMA G GV L+++ Sbjct: 236 RPAVQVGDPFLEKGLIEACLEAFDSGDVVAAQDMGAAGLTCSCSEMAAKGGLGVELDLDR 295 Query: 570 -------LKDNDLLQTLFAEELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIE 728 + + L + E + V++ ++ + ++ G+ A V+G+V P + Sbjct: 296 VPARESGMTAYEFLLSESQERMLFVVKAGREE--PLMKRFRRWGLQAAVVGQVLEEPIVR 353 Query: 729 LLVDGEVR-------------------LKERTSDLRDLWEETSFQLEEL 818 +L GEV L E DL++ W+ T QL +L Sbjct: 354 VLHHGEVAAEVPATALADDTPIEKHALLSEPPVDLQEHWQWTEAQLPDL 402
>Q63GT3:PURL_BACCZ Phosphoribosylformylglycinamidine synthase II - Bacillus cereus| (strain ZK / E33L) Length = 739 Score = 47.8 bits (112), Expect = 2e-04 Identities = 49/179 (27%), Positives = 84/179 (46%), Gaps = 3/179 (1%) Frame = +3 Query: 264 DITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFD-QIGNDCPDIEDVPYLKKVF 440 D+ T + K D V + + + K G S L + +I P I+ LK+ Sbjct: 564 DLKHVTTQEFKQAGDLVYV---IGETKAEFGGSELQKMLHGKIFGQSPSIDLGVELKRQK 620 Query: 441 EVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE-ELG 617 +V+ + + L+ + HD+++GGL V I E A N G+ ++L D + LFAE + Sbjct: 621 QVLAAIQAG-LVQSAHDVAEGGLAVAISESAIGAN-GLGATVKL-DGEATAALFAESQSR 677 Query: 618 LVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIEL-LVDGEVRLKERTSDLRDLWE 791 VI V ++ +V ++ V A +GEVT E+ + + EV L ++R W+ Sbjct: 678 FVITVKRENKEVFEK-----AVEAIQVGEVTNTNEVTIHNEENEVLLTANVDEMRKAWK 731
>Q6FZI9:PURL_BARQU Phosphoribosylformylglycinamidine synthase II - Bartonella quintana| (Rochalimaea quintana) Length = 736 Score = 47.4 bits (111), Expect = 2e-04 Identities = 35/144 (24%), Positives = 63/144 (43%) Frame = +3 Query: 276 TVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQE 455 TVT KD ++L + LG S A+ I P D+ KK + V++ Sbjct: 563 TVTIGGMQNKDSIVL---IGPCGSHLGQSIYARNILNIDAGAPPHIDLQLEKKHGQFVRD 619 Query: 456 LLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAEELGLVIEVH 635 ++ ++A HDISDGGL + + EM + G+ + + K + ++ ++ V Sbjct: 620 VIHRGFVNAAHDISDGGLALALAEMVIKASKGIRIKLSNKSPQHAELFGEDQARYILAVK 679 Query: 636 LDDLDVVKQKLHAAGVSANVIGEV 707 L+ +K+ +S +G V Sbjct: 680 PHALNSLKELAQVNEISLTELGTV 703
>Q2RGU5:PURL_MOOTA Phosphoribosylformylglycinamidine synthase 2 - Moorella| thermoacetica (strain ATCC 39073) Length = 733 Score = 47.0 bits (110), Expect = 3e-04 Identities = 38/136 (27%), Positives = 65/136 (47%), Gaps = 4/136 (2%) Frame = +3 Query: 402 PDIEDVPYLKKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCG--VNLNIELK 575 P D+ K V +V+E+++ L +A HD ++GGL V + E A AG G V L +L+ Sbjct: 596 PPALDLEREKAVQALVREVIAAGLATAAHDCAEGGLAVALAESALAGGLGAEVELASDLR 655 Query: 576 DNDLLQTLFAEELGLVIEVHLDD--LDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEV 749 + LL + + L + D LD+ ++K GV A+VIG + + ++G Sbjct: 656 PDFLLFSESQSRILLAVAPEARDRVLDLAREK----GVRASVIGR-CGGHSLVVRINGRT 710 Query: 750 RLKERTSDLRDLWEET 797 ++ W E+ Sbjct: 711 LFNLSLEEMGKQWRES 726
>Q81IQ3:PURL_BACCR Phosphoribosylformylglycinamidine synthase II - Bacillus cereus| (strain ATCC 14579 / DSM 31) Length = 739 Score = 47.0 bits (110), Expect = 3e-04 Identities = 49/179 (27%), Positives = 84/179 (46%), Gaps = 3/179 (1%) Frame = +3 Query: 264 DITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFD-QIGNDCPDIEDVPYLKKVF 440 D+ T + K D V + + + K G S L + +I P I+ LK+ Sbjct: 564 DLKHVTTQEFKQAGDLVYV---IGETKAEFGGSELQKMIHGKIFGQSPSIDLDVELKRQK 620 Query: 441 EVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE-ELG 617 +V+ E + L+ + HD+++GGL V I E A G G+ ++L D + LFAE + Sbjct: 621 QVL-EAIQAGLVQSAHDVAEGGLAVAISESAI-GAKGLGATVKL-DGEATAALFAESQSR 677 Query: 618 LVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIEL-LVDGEVRLKERTSDLRDLWE 791 VI V ++ + ++ V A +GEVT+ E+ + + EV L ++R W+ Sbjct: 678 FVITVKRENKEAFEKV-----VEAIQVGEVTSTNEVTIHNEENEVLLTANVDEMRKAWK 731
>Q2NEB6:PURL_METST Phosphoribosylformylglycinamidine synthase 2 - Methanosphaera| stadtmanae (strain DSM 3091) Length = 723 Score = 46.6 bits (109), Expect = 4e-04 Identities = 46/165 (27%), Positives = 73/165 (44%), Gaps = 35/165 (21%) Frame = +3 Query: 387 IGNDCPDIEDVPYLKKVFEVVQ--------------ELLSERLI-------SAGHDISDG 503 +GN P+++ Y K + VVQ E+LI ++ HDIS G Sbjct: 556 VGNTYPELDGSQYYKHIHNVVQGYPPKIRLEENYNVSTTIEKLIPKYNDNITSVHDISKG 615 Query: 504 GLIVTILEMAFAGNCGVNLNI-------ELKDNDLLQTLFAEELGLVIEVHLDDLDVVKQ 662 GLI+ + M+ GVN+NI EL +D L + +I V D L +++ Sbjct: 616 GLIIALALMSIKSKKGVNVNISNIPSTTELSQDDKLYS--ESNSRFIITVKEDALTTIEE 673 Query: 663 KLHAAGVSANVIGEVTA-----APEIELLVDGEVR--LKERTSDL 776 L V+ +VIG V + + + ++LVD V KE T+ + Sbjct: 674 ALSKNNVAYSVIGSVCSDGFKISNDNDVLVDCSVEKITKENTTTI 718
>Q2RZ77:PURL_SALRD Phosphoribosylformylglycinamidine synthase 2 - Salinibacter ruber| (strain DSM 13855) Length = 754 Score = 46.2 bits (108), Expect = 5e-04 Identities = 42/134 (31%), Positives = 58/134 (43%), Gaps = 3/134 (2%) Frame = +3 Query: 327 DLAKGKRRLGCSALAQAFDQIGNDCPDIEDVPYLKKVFEVVQELLSERLISAGHDISDGG 506 D +R G L+ D+ D P + D+ V Q L+ E L+ HD+SDGG Sbjct: 592 DWCHPERTDGSEYLSTVHDRTAGDAPHL-DLDEEVAVQSATQALIREGLVQHAHDVSDGG 650 Query: 507 LIVTILEMAFAGNCGVNLNIELKDNDLLQ-TLFAE-ELGLVIEVHLDDLDVVKQKL-HAA 677 L V + E + G+ L L D L LF E + +V+ V DD + L Sbjct: 651 LAVCLAESVIHSD-GLGLEATLPAADRLDAALFGEAQSRVVVSVRPDDALALDAALTDHN 709 Query: 678 GVSANVIGEVTAAP 719 GV A +G VT P Sbjct: 710 GVRARRLGAVTTGP 723
>Q73EN5:PURL_BACC1 Phosphoribosylformylglycinamidine synthase II - Bacillus cereus| (strain ATCC 10987) Length = 739 Score = 46.2 bits (108), Expect = 5e-04 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 3/179 (1%) Frame = +3 Query: 264 DITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFD-QIGNDCPDIEDVPYLKKVF 440 D+ T + K D V + + + K G S L + +I P I+ LK+ Sbjct: 564 DLKHVTTQEFKQAGDLVYV---IGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQK 620 Query: 441 EVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE-ELG 617 +V+ + + L+ + HD+++GGL V I E A N G+ ++L D + LFAE + Sbjct: 621 QVLAAIQAG-LVQSAHDVAEGGLAVAISESAIGAN-GLGATVKL-DGEATAALFAESQSR 677 Query: 618 LVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIEL-LVDGEVRLKERTSDLRDLWE 791 VI V ++ + ++ V A +GEVT E+ + + EV L ++R W+ Sbjct: 678 FVITVKRENKEAFEK-----AVEAIQVGEVTNTNEVTIHNEENEVLLTANVDEMRKAWK 731
>Q81ZH2:PURL_BACAN Phosphoribosylformylglycinamidine synthase II - Bacillus anthracis| Length = 739 Score = 46.2 bits (108), Expect = 5e-04 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 3/179 (1%) Frame = +3 Query: 264 DITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFD-QIGNDCPDIEDVPYLKKVF 440 D+ T + K D V + + + K G S L + +I P I+ LK+ Sbjct: 564 DLKHVTTQEFKQAGDLVYV---IGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQK 620 Query: 441 EVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE-ELG 617 +V+ + + L+ + HD+++GGL V I E A N G+ ++L D + LFAE + Sbjct: 621 QVLAAIQAG-LVQSAHDVAEGGLAVAISESAIGAN-GLGATVKL-DGEATAALFAESQSR 677 Query: 618 LVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIEL-LVDGEVRLKERTSDLRDLWE 791 VI V ++ + ++ V A +GEVT E+ + + EV L ++R W+ Sbjct: 678 FVITVKRENKEAFEK-----AVEAIQVGEVTNTNEVTIHNEENEVLLTANVDEMRKAWK 731
>Q7V3R5:PURL_PROMP Phosphoribosylformylglycinamidine synthase II - Prochlorococcus| marinus subsp. pastoris (strain CCMP 1378 / MED4) Length = 779 Score = 45.8 bits (107), Expect = 7e-04 Identities = 44/183 (24%), Positives = 85/183 (46%), Gaps = 7/183 (3%) Frame = +3 Query: 420 PYLKK-VFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIEL---KDNDL 587 P+++K + E + + + D+ GL + EMA G+ G+++N++L ++ND+ Sbjct: 247 PFIEKSLIEACLDAFKTGDVLSAQDMGAAGLTCSSAEMAANGSLGISINLDLVPARENDM 306 Query: 588 --LQTLFAE-ELGLVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLK 758 Q L +E + +++ V + L+ + + G+ ANVIGEV + E+ + ++ + Sbjct: 307 SAYQYLLSESQERMLLVVKEEKLNTLINQFKKWGLFANVIGEVISRKEVIISQKNQIVAQ 366 Query: 759 ERTSDLRDLWEETSFQLEELQRLKSCVKLEKEGLKSRTSPLWHLSFTPKFTDKKLLSASS 938 TS L D ET + + + LEK W P ++ K+LS Sbjct: 367 IPTSALSD---ETPINIHNIIKEPPIHLLEKWE--------WTEEELPAISENKILSLKD 415 Query: 939 KPK 947 + K Sbjct: 416 QQK 418 Score = 34.7 bits (78), Expect = 1.5 Identities = 16/54 (29%), Positives = 30/54 (55%) Frame = +3 Query: 447 VQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE 608 +++ + + I++ HD+SDGGL V + E + G + +E K+ LF+E Sbjct: 652 LRDSIQKNYIASSHDVSDGGLAVALSECCILSSKGAYIQLEEKNARQDNLLFSE 705
>Q6HPA4:PURL_BACHK Phosphoribosylformylglycinamidine synthase II - Bacillus| thuringiensis subsp. konkukian Length = 739 Score = 45.8 bits (107), Expect = 7e-04 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 3/179 (1%) Frame = +3 Query: 264 DITLTVTPDLKLGKDGVLLHVDLAKGKRRLGCSALAQAFD-QIGNDCPDIEDVPYLKKVF 440 D+ T + K D V + + + K G S L + +I P I+ LK+ Sbjct: 564 DLKHVTTQEFKQAGDLVYV---IGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQK 620 Query: 441 EVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE-ELG 617 +V+ + + L+ + HD+++GGL V I E A N G+ ++L D + LFAE + Sbjct: 621 QVLAAIQAG-LVQSAHDVAEGGLAVAISESAIGAN-GLGATVKL-DGEATAALFAESQSR 677 Query: 618 LVIEVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVD-GEVRLKERTSDLRDLWE 791 VI V ++ + ++ V A +GEVT E+ + + EV L ++R W+ Sbjct: 678 FVITVKRENKEAFEK-----AVEAIQVGEVTNTNEVTIHNEKNEVLLTANVDEMRKAWK 731
>Q5SMH8:PURL_THET8 Phosphoribosylformylglycinamidine synthase II - Thermus| thermophilus (strain HB8 / ATCC 27634 / DSM 579) Length = 725 Score = 45.4 bits (106), Expect = 9e-04 Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 1/122 (0%) Frame = +3 Query: 429 KKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE 608 K V E +++L+ L HD+++GGL++ + EM F GV +E+++ L+ LF E Sbjct: 600 KAVQEAIRDLIQRGLTRTAHDVAEGGLLLALAEMTFP--YGVGATVEVREEG-LEALFGE 656 Query: 609 ELGLVI-EVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDLRDL 785 V+ V L L G+ V+GE T + +L G V L+ +L Sbjct: 657 APSRVLFTVEKTRLQEATLLLEERGLPYRVLGE-TGGKSLTVLTPGGV-LEWSLEELLSA 714 Query: 786 WE 791 W+ Sbjct: 715 WK 716
>Q72IH7:PURL_THET2 Phosphoribosylformylglycinamidine synthase II - Thermus| thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) Length = 725 Score = 45.4 bits (106), Expect = 9e-04 Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 1/122 (0%) Frame = +3 Query: 429 KKVFEVVQELLSERLISAGHDISDGGLIVTILEMAFAGNCGVNLNIELKDNDLLQTLFAE 608 K V E +++L+ L HD+++GGL++ + EM F GV +E+++ L+ LF E Sbjct: 600 KAVQEAIRDLIQRGLTRTAHDVAEGGLLLALAEMTFP--YGVGATVEVREEG-LEALFGE 656 Query: 609 ELGLVI-EVHLDDLDVVKQKLHAAGVSANVIGEVTAAPEIELLVDGEVRLKERTSDLRDL 785 V+ V L L G+ V+GE T + +L G V L+ +L Sbjct: 657 APSRVLFTVEKTRLQEATLLLEERGLPYRVLGE-TGGKSLTVLTPGGV-LEWSLEELLSA 714 Query: 786 WE 791 W+ Sbjct: 715 WK 716 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 364,851,900 Number of extensions: 8393675 Number of successful extensions: 23935 Number of sequences better than 10.0: 353 Number of HSP's gapped: 23200 Number of HSP's successfully gapped: 381 Length of query: 667 Length of database: 100,686,439 Length adjustment: 120 Effective length of query: 547 Effective length of database: 67,771,039 Effective search space: 37070758333 Effective search space used: 37070758333 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
