ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf34j17 |
|---|---|
| Clone Library Name | barley_pub |
>Q69ZH9:RHG23_MOUSE Rho GTPase-activating protein 23 - Mus musculus (Mouse)| Length = 1483 Score = 80.9 bits (198), Expect = 1e-14 Identities = 65/243 (26%), Positives = 115/243 (47%), Gaps = 24/243 (9%) Frame = +2 Query: 449 LNNIERWQKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEG 628 +N I++ +K A+ FG+ +E Q + VPLI+ C + GL + +++ G Sbjct: 885 INIIKKNKK--AAPRAFGIRLEE-CQPATENQRVPLIVAACCRIVEARGLESTGIYRVPG 941 Query: 629 DRKVLQQL----------VSLYNE--------AALIKCYLASIPEPLTTFALYDE----- 739 + V+ L ++L +E ++L+K + +PEPL T Y++ Sbjct: 942 NNAVVSSLQEQLNRGPSDINLQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEAN 1001 Query: 740 -LKDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 ++D+R + L+ +++ LP Y TL+F+ L ++ S NKM+ R LA+ F P ++ Sbjct: 1002 RIEDSRERMKTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLV 1061 Query: 917 WQQGDSGTDLRNHLRFTLKPPPKIVDTTSTITWDLLDEDDVDASSQIPLDDASPPDYGAI 1096 D+ TD+ H + KIV+T + D DD D + P+DD P I Sbjct: 1062 RTSEDNMTDMVTH----MPDRYKIVETLIQHS-DWFFSDDEDKGERTPVDDKEPQSVPNI 1116 Query: 1097 EVI 1105 E + Sbjct: 1117 EYL 1119
>Q5U2Z7:RHG24_RAT Rho GTPase-activating protein 24 - Rattus norvegicus (Rat)| Length = 748 Score = 77.0 bits (188), Expect = 2e-13 Identities = 49/187 (26%), Positives = 87/187 (46%), Gaps = 32/187 (17%) Frame = +2 Query: 452 NNIERWQKGVA-------SSDVFGVPVEATAQREQ--SGKAVPLILVRCADHLVISGLSN 604 N++E W K + +FG +E T + E+ + P+++ +C D + GL Sbjct: 110 NDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKE 169 Query: 605 EYLFKSEGDRKVLQQL---------------VSLYNEAALIKCYLASIPEPLTTFALYDE 739 E LF+ G ++++L ++ A+L+K YL +PEP+ +A Y++ Sbjct: 170 EGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYED 229 Query: 740 L--------KDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAV 895 K+ + +L +K LP VNY L+++ L V S +NKM ++ LA Sbjct: 230 FLSCATLLSKEEEAGVKELTKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLAT 289 Query: 896 EFAPLII 916 F P I+ Sbjct: 290 VFGPNIL 296
>Q8C4V1:RHG24_MOUSE Rho GTPase-activating protein 24 - Mus musculus (Mouse)| Length = 747 Score = 77.0 bits (188), Expect = 2e-13 Identities = 49/187 (26%), Positives = 87/187 (46%), Gaps = 32/187 (17%) Frame = +2 Query: 452 NNIERWQKGVA-------SSDVFGVPVEATAQREQ--SGKAVPLILVRCADHLVISGLSN 604 N++E W K + +FG +E T + E+ + P+++ +C D + GL Sbjct: 109 NDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKE 168 Query: 605 EYLFKSEGDRKVLQQL---------------VSLYNEAALIKCYLASIPEPLTTFALYDE 739 E LF+ G ++++L ++ A+L+K YL +PEP+ +A Y++ Sbjct: 169 EGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYED 228 Query: 740 L--------KDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAV 895 K+ + +L +K LP VNY L+++ L V S +NKM ++ LA Sbjct: 229 FLSCATLLSKEEEAGVKELMKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLAT 288 Query: 896 EFAPLII 916 F P I+ Sbjct: 289 VFGPNIL 295
>Q9P227:RHG23_HUMAN Rho GTPase-activating protein 23 - Homo sapiens (Human)| Length = 1491 Score = 76.6 bits (187), Expect = 2e-13 Identities = 65/243 (26%), Positives = 114/243 (46%), Gaps = 24/243 (9%) Frame = +2 Query: 449 LNNIERWQKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEG 628 +N I++ +K A+ FGV +E Q + VPLI+ C + GL + +++ G Sbjct: 889 INIIKKNKK--AAPRAFGVRLEE-CQPATENQRVPLIVAACCRIVEARGLESTGIYRVPG 945 Query: 629 DRKVLQQL----------VSLYNE--------AALIKCYLASIPEPLTTFALYDE----- 739 + V+ L ++L +E ++L+K + +PEPL T Y++ Sbjct: 946 NNAVVSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEAN 1005 Query: 740 -LKDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 ++DAR + L+ +++ LP Y TL+F+ L ++ S NKM+ R LA+ F P ++ Sbjct: 1006 RIEDARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLV 1065 Query: 917 WQQGDSGTDLRNHLRFTLKPPPKIVDTTSTITWDLLDEDDVDASSQIPLDDASPPDYGAI 1096 D+ TD+ H + KIV+T + D D+ D + P+ D P I Sbjct: 1066 RTSEDNMTDMVTH----MPDRYKIVETLIQHS-DWFFSDEEDKGERTPVGDKEPQAVPNI 1120 Query: 1097 EVI 1105 E + Sbjct: 1121 EYL 1123
>Q07960:RHG01_HUMAN Rho GTPase-activating protein 1 - Homo sapiens (Human)| Length = 439 Score = 76.6 bits (187), Expect = 2e-13 Identities = 44/161 (27%), Positives = 78/161 (48%), Gaps = 20/161 (12%) Frame = +2 Query: 497 FGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYN--- 667 FGV ++ ++ + +P++L +L L+ E +F+ + +V++++ YN Sbjct: 242 FGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGL 301 Query: 668 ------------EAALIKCYLASIPEPLTTFALYDELK-----DARVSIDDLKNILKKLP 796 A ++K +L +PEPL TF LY + D + +L+ LP Sbjct: 302 PVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLP 361 Query: 797 NVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIW 919 NY L F+T+ L+++S S NKM + LAV F P ++W Sbjct: 362 EENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLW 402
>Q8N264:RHG24_HUMAN Rho GTPase-activating protein 24 - Homo sapiens (Human)| Length = 748 Score = 75.5 bits (184), Expect = 5e-13 Identities = 49/187 (26%), Positives = 86/187 (45%), Gaps = 32/187 (17%) Frame = +2 Query: 452 NNIERWQKGVA-------SSDVFGVPVEATAQREQ--SGKAVPLILVRCADHLVISGLSN 604 N++E W K + +FG +E T + E+ + P+++ +C D + GL Sbjct: 111 NDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKE 170 Query: 605 EYLFKSEGDRKVLQQL---------------VSLYNEAALIKCYLASIPEPLTTFALYDE 739 E LF+ G ++++L ++ A+L+K YL +PEP+ +A Y++ Sbjct: 171 EGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYED 230 Query: 740 L--------KDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAV 895 K+ + +L +K LP VNY L+++ L V S +NKM + LA Sbjct: 231 FLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLAT 290 Query: 896 EFAPLII 916 F P I+ Sbjct: 291 VFGPNIL 297
>Q9NSG0:RHG08_HUMAN Rho GTPase-activating protein 8 - Homo sapiens (Human)| Length = 718 Score = 74.7 bits (182), Expect = 9e-13 Identities = 46/161 (28%), Positives = 80/161 (49%), Gaps = 20/161 (12%) Frame = +2 Query: 497 FGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE-- 670 FGV ++ + Q G+ +P +L +L GL E LF+ + ++++ LYN+ Sbjct: 478 FGVSLQYLKDKNQ-GELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGK 536 Query: 671 -------------AALIKCYLASIPEPLTTFALYDELK-----DARVSIDDLKNILKKLP 796 A ++K +L +P+PL TF Y+++ ++ + + + IL+ LP Sbjct: 537 PVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLP 596 Query: 797 NVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIW 919 NY+ L ++ L VSR+S NKM+S LA F +IW Sbjct: 597 EHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIW 637
>Q8BL80:RHG22_MOUSE Rho GTPase-activating protein 22 - Mus musculus (Mouse)| Length = 702 Score = 72.4 bits (176), Expect = 4e-12 Identities = 54/190 (28%), Positives = 82/190 (43%), Gaps = 31/190 (16%) Frame = +2 Query: 494 VFGVPVEATAQREQS--GKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL----- 652 +FG +E T E+ + PL++ +C D + GLS E LF+ G +++ L Sbjct: 158 IFGQRLEDTVHHERKFGPRLAPLLVEQCVDFIRERGLSEEGLFRMPGQANLVRDLQDSFD 217 Query: 653 ----------VSLYNEAALIKCYLASIPEPLTTFALYDEL--------KDARVSIDDLKN 778 ++ A+L+K YL +PEP+ FA Y++ KD +L Sbjct: 218 CGEKPLFDSTTDVHTVASLLKLYLRELPEPVIPFARYEDFLSCAQLLTKDEGEGTVELAK 277 Query: 779 ILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGD------SGT 940 + LP NY L ++ L V S +NKM + LA F P I+ Q + GT Sbjct: 278 QVSNLPQANYNLLRYICKFLDEVQAHSDVNKMSVQNLATVFGPNILRPQIEDPVTIMEGT 337 Query: 941 DLRNHLRFTL 970 L HL L Sbjct: 338 SLVQHLMTVL 347
>Q7Z5H3:RHG22_HUMAN Rho GTPase-activating protein 22 - Homo sapiens (Human)| Length = 698 Score = 72.0 bits (175), Expect = 6e-12 Identities = 53/190 (27%), Positives = 83/190 (43%), Gaps = 31/190 (16%) Frame = +2 Query: 494 VFGVPVEATA--QREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL----- 652 +FG +E T +R+ + PL++ +C D + GL+ E LF+ G +++ L Sbjct: 152 IFGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFD 211 Query: 653 ----------VSLYNEAALIKCYLASIPEPLTTFALYDEL--------KDARVSIDDLKN 778 ++ A+L+K YL +PEP+ FA Y++ KD +L Sbjct: 212 CGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAK 271 Query: 779 ILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGD------SGT 940 + LP NY L ++ L V S +NKM + LA F P I+ Q + GT Sbjct: 272 QVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGT 331 Query: 941 DLRNHLRFTL 970 L HL L Sbjct: 332 SLVQHLMTVL 341
>P81128:GRLF1_RAT Glucocorticoid receptor DNA-binding factor 1 - Rattus norvegicus| (Rat) Length = 1513 Score = 71.6 bits (174), Expect = 7e-12 Identities = 45/171 (26%), Positives = 85/171 (49%), Gaps = 23/171 (13%) Frame = +2 Query: 473 KGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL 652 K S+ FGVP+ E K +P+ + RC +++ +GLS E +++ G++ ++ L Sbjct: 1239 KATWESNYFGVPLTTVVTPE---KPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESL 1295 Query: 653 VSLYNE----------------AALIKCYLASIPEPLTTFALYDELKDARVSIDD----- 769 +++ A +K + + +P+PL +++ +L +A I+D Sbjct: 1296 QRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAH-KINDREQKL 1354 Query: 770 --LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 LK +LKK P N+ ++V S L RVS + +N M S L++ F P ++ Sbjct: 1355 HALKEVLKKFPKENHEVFKYVISHLNRVSHNNKVNLMTSENLSICFWPTLM 1405
>Q68EM7:RHG17_HUMAN Rho GTPase-activating protein 17 - Homo sapiens (Human)| Length = 881 Score = 70.9 bits (172), Expect = 1e-11 Identities = 46/171 (26%), Positives = 82/171 (47%), Gaps = 21/171 (12%) Frame = +2 Query: 482 ASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVS- 658 A FG P+E +R SG+ + L + C L+ +G+ E LF+ L++L + Sbjct: 245 AEKPAFGTPLEEHLKR--SGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAA 302 Query: 659 ----------LYNE----AALIKCYLASIPEPLTTFALYDE------LKDARVSIDDLKN 778 Y++ A +K YL +PEPL TF LY+E ++D + DL Sbjct: 303 LDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWR 362 Query: 779 ILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGD 931 +KLP N++ ++ L ++++ S +NKM +A+ P ++W + + Sbjct: 363 TCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNE 413
>Q91YM2:GRLF1_MOUSE Glucocorticoid receptor DNA-binding factor 1 - Mus musculus (Mouse)| Length = 1499 Score = 70.5 bits (171), Expect = 2e-11 Identities = 44/171 (25%), Positives = 85/171 (49%), Gaps = 23/171 (13%) Frame = +2 Query: 473 KGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL 652 K S+ FGVP+ E K +P+ + RC +++ +GLS E +++ G++ ++ L Sbjct: 1239 KATWESNYFGVPLTTVVTPE---KPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESL 1295 Query: 653 VSLYNE----------------AALIKCYLASIPEPLTTFALYDELKDARVSIDD----- 769 +++ A +K + + +P+PL +++ +L +A I+D Sbjct: 1296 QRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAH-KINDREQKL 1354 Query: 770 --LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 LK +LKK P N+ ++V S L +VS + +N M S L++ F P ++ Sbjct: 1355 HALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLM 1405
>Q9CXP4:RHG08_MOUSE Rho GTPase-activating protein 8 - Mus musculus (Mouse)| Length = 425 Score = 69.3 bits (168), Expect = 4e-11 Identities = 45/161 (27%), Positives = 78/161 (48%), Gaps = 20/161 (12%) Frame = +2 Query: 497 FGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE-- 670 FGV ++ + Q G+ +P +L +L GL E LF+ + ++Q+ LY++ Sbjct: 193 FGVSLQYLRDKNQ-GELIPPVLRWTVTYLREKGLRTEGLFRRSASAQTVRQVQRLYDQGK 251 Query: 671 -------------AALIKCYLASIPEPLTTFALYDELK-----DARVSIDDLKNILKKLP 796 A ++K +L +P+PL TF Y+++ ++ + + + IL+ LP Sbjct: 252 PVNFDDYGDMHLPAVILKTFLRELPQPLLTFQAYEQILGITSVESSLRVTHCRLILRSLP 311 Query: 797 NVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIW 919 NY L ++ L VS +S NKM+S LA F +IW Sbjct: 312 EHNYAVLRYLMGFLHEVSLESISNKMNSSNLACVFGLNLIW 352
>Q9NRY4:GRLF1_HUMAN Glucocorticoid receptor DNA-binding factor 1 - Homo sapiens (Human)| Length = 1513 Score = 69.3 bits (168), Expect = 4e-11 Identities = 44/171 (25%), Positives = 84/171 (49%), Gaps = 23/171 (13%) Frame = +2 Query: 473 KGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL 652 K S+ FGVP+ E K +P+ + RC +++ +GLS E +++ G++ ++ L Sbjct: 1239 KATWESNYFGVPLTTVVTPE---KPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESL 1295 Query: 653 VSLYNE----------------AALIKCYLASIPEPLTTFALYDELKDARVSIDD----- 769 +++ A +K + + +P+PL + + +L +A I+D Sbjct: 1296 QRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAH-KINDREQKL 1354 Query: 770 --LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 LK +LKK P N+ ++V S L +VS + +N M S L++ F P ++ Sbjct: 1355 HALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLM 1405
>P83509:GRLF1_CANFA Glucocorticoid receptor DNA-binding factor 1 - Canis familiaris (Dog)| Length = 1500 Score = 68.9 bits (167), Expect = 5e-11 Identities = 44/171 (25%), Positives = 84/171 (49%), Gaps = 23/171 (13%) Frame = +2 Query: 473 KGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL 652 K S+ FGVP+ E K +P+ + RC +++ +GLS E +++ G++ ++ L Sbjct: 1240 KATWESNYFGVPLTTVVTPE---KPIPVFIERCIEYIEATGLSTEGIYRVSGNKSEMESL 1296 Query: 653 VSLYNE----------------AALIKCYLASIPEPLTTFALYDELKDARVSIDD----- 769 +++ A +K + + +P+PL + + +L +A I+D Sbjct: 1297 QRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAH-KINDREQKL 1355 Query: 770 --LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 LK +LKK P N+ ++V S L +VS + +N M S L++ F P ++ Sbjct: 1356 HALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLM 1406
>Q5SSM3:RICH2_MOUSE Rho GTPase-activating protein RICH2 - Mus musculus (Mouse)| Length = 814 Score = 67.8 bits (164), Expect = 1e-10 Identities = 48/185 (25%), Positives = 82/185 (44%), Gaps = 21/185 (11%) Frame = +2 Query: 440 KTILNNIERWQKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFK 619 + +L I+ Q+ FG P+E SG+ + + C L+ G+ E LF+ Sbjct: 234 QAVLPQIKAQQEAWVEKPSFGKPLEEHLMI--SGREIAFPIEACVTMLLECGMQEEGLFR 291 Query: 620 SEGDRKVLQQL----------VSLYNE-----AALIKCYLASIPEPLTTFALYDE----- 739 L++L V Y+ A +K YL +PEPL TF LYDE Sbjct: 292 VAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQAS 351 Query: 740 -LKDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 +++ + L N +KLP N+ ++++ L ++S +NKM +A+ P ++ Sbjct: 352 NIQEQDKRLQALWNACEKLPKANHNNIKYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL 411 Query: 917 WQQGD 931 W Q + Sbjct: 412 WPQSE 416
>Q17R89:RICH2_HUMAN Rho GTPase-activating protein RICH2 - Homo sapiens (Human)| Length = 818 Score = 67.8 bits (164), Expect = 1e-10 Identities = 50/185 (27%), Positives = 82/185 (44%), Gaps = 21/185 (11%) Frame = +2 Query: 440 KTILNNIERWQKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFK 619 + +L I+ Q+ FG P+E SG+ + + C L+ G+ E LF+ Sbjct: 234 QAVLPQIKAQQEAWVEKPSFGKPLEE--HLTISGREIAFPIEACVTMLLECGMQEEGLFR 291 Query: 620 SEGDRKVLQQL----------VSLYNE-----AALIKCYLASIPEPLTTFALYDE-LKDA 751 L++L V Y+ A +K YL +PEPL TF LYDE ++ + Sbjct: 292 VAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQAS 351 Query: 752 RVSIDDLK-----NILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 V D K N +KLP N+ + ++ L ++S +NKM +A+ P ++ Sbjct: 352 NVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL 411 Query: 917 WQQGD 931 W Q + Sbjct: 412 WPQAE 416
>Q99N37:RHG17_RAT Rho GTPase-activating protein 17 - Rattus norvegicus (Rat)| Length = 858 Score = 67.8 bits (164), Expect = 1e-10 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 21/167 (12%) Frame = +2 Query: 482 ASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVS- 658 A FG P+E +R SG+ + L + C L+ +G+ E LF+ L++L + Sbjct: 245 AEKPAFGTPLEEHLKR--SGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAA 302 Query: 659 ----------LYNE----AALIKCYLASIPEPLTTFALYDE------LKDARVSIDDLKN 778 Y++ A +K YL +PEPL TF+LY+E ++D + L Sbjct: 303 LDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWT 362 Query: 779 ILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIW 919 +KLP N++ ++ L ++++ S +NKM +A+ P ++W Sbjct: 363 TCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLW 409
>Q3UIA2:RHG17_MOUSE Rho GTPase-activating protein 17 - Mus musculus (Mouse)| Length = 846 Score = 67.8 bits (164), Expect = 1e-10 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 21/167 (12%) Frame = +2 Query: 482 ASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVS- 658 A FG P+E +R SG+ + L + C L+ +G+ E LF+ L++L + Sbjct: 245 AEKPAFGTPLEEHLKR--SGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAA 302 Query: 659 ----------LYNE----AALIKCYLASIPEPLTTFALYDE------LKDARVSIDDLKN 778 Y++ A +K YL +PEPL TF+LY+E ++D + L Sbjct: 303 LDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWT 362 Query: 779 ILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIW 919 +KLP N++ ++ L ++++ S +NKM +A+ P ++W Sbjct: 363 TCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLW 409
>P34288:GAP_CAEEL GTPase-activating protein GAP - Caenorhabditis elegans| Length = 1317 Score = 67.0 bits (162), Expect = 2e-10 Identities = 48/153 (31%), Positives = 76/153 (49%), Gaps = 9/153 (5%) Frame = +2 Query: 671 AALIKCYLASIPEPLTTFALYDELKDA-RVS-----IDDLKNILKKLPNVNYMTLEFVTS 832 ++L+K +L +PEPL T LY DA R+S + L+N+L+KLP +Y TL F+ Sbjct: 739 SSLLKMFLRKLPEPLLTDKLYPFFIDANRISTHHNRLHKLRNLLRKLPRPHYDTLRFLIV 798 Query: 833 LLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLRNHLRFTLKPPPKIVDTTSTIT 1012 L +++ S +NKM+ R LA+ F P I+ D+ + H + KI++T Sbjct: 799 HLSEITKHSDVNKMECRNLALMFGPSIVRPSDDNMATMVTH----MSDQCKIIETLIHYN 854 Query: 1013 WDLLDEDDVDASS---QIPLDDASPPDYGAIEV 1102 + DE + Q P D +P + G V Sbjct: 855 LWMFDESSTTEDAVPEQHPADGQNPLEPGGYGV 887
>Q7Z6I6:RHG30_HUMAN Rho GTPase-activating protein 30 - Homo sapiens (Human)| Length = 1101 Score = 66.2 bits (160), Expect = 3e-10 Identities = 50/172 (29%), Positives = 88/172 (51%), Gaps = 23/172 (13%) Frame = +2 Query: 470 QKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLV----------ISGLSN----- 604 +KG A VFG ++ Q SG+ VP +L CA+ + +SG+S+ Sbjct: 9 KKGSAKERVFGCDLQEHLQH--SGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVSSNIQKL 66 Query: 605 --EYLFKSEGDRKVLQQLVSLYNEAALIKCYLASIPEPLTTFALYDELKDA-RVSIDD-- 769 E+ + + D + L ++ ++L K Y +P+PL T+ LYD+ +A V ++ Sbjct: 67 RQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPER 126 Query: 770 ---LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 + +L++LP NY TLEF+ L+ ++ SA M +R LA+ +AP ++ Sbjct: 127 LVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLL 178
>Q9Y3L3:3BP1_HUMAN SH3 domain-binding protein 1 - Homo sapiens (Human)| Length = 701 Score = 66.2 bits (160), Expect = 3e-10 Identities = 45/170 (26%), Positives = 77/170 (45%), Gaps = 24/170 (14%) Frame = +2 Query: 494 VFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSL---- 661 V+GV + Q + G+ + L + C L+ G+ E LF+ VL++L Sbjct: 273 VYGVSLATHLQ--ELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASD 330 Query: 662 -----------YNEAALIKCYLASIPEPLTTFALYDE------LKDARVSIDDLKNILKK 790 + A +K YL +PEPL TF LYD+ LK+ + L+ + + Sbjct: 331 PHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSR 390 Query: 791 LPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIW---QQGD 931 LP N L ++ L R++ + +NKM +A+ P ++W ++GD Sbjct: 391 LPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGD 440
>Q640N3:RHG30_MOUSE Rho GTPase-activating protein 30 - Mus musculus (Mouse)| Length = 1101 Score = 63.9 bits (154), Expect = 2e-09 Identities = 49/172 (28%), Positives = 87/172 (50%), Gaps = 23/172 (13%) Frame = +2 Query: 470 QKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLV----------ISGLSN----- 604 +KG + VFG + Q SG+ VP +L CA+ + +SG+S+ Sbjct: 9 KKGSSKERVFGCDLREHLQH--SGQEVPQVLRSCAEFVQEYGVVDGIYRLSGVSSNIQKL 66 Query: 605 --EYLFKSEGDRKVLQQLVSLYNEAALIKCYLASIPEPLTTFALYDELKDA-RVSIDD-- 769 E+ + + D + L ++ ++L K Y +P+PL T+ LYD+ +A V ++ Sbjct: 67 RQEFETERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVAVQLEPER 126 Query: 770 ---LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 + +L++LP NY TLEF+ L+ ++ SA M +R LA+ +AP ++ Sbjct: 127 LVKILEVLQELPIQNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLL 178
>Q12979:ABR_HUMAN Active breakpoint cluster region-related protein - Homo sapiens| (Human) Length = 859 Score = 63.9 bits (154), Expect = 2e-09 Identities = 44/164 (26%), Positives = 74/164 (45%), Gaps = 23/164 (14%) Frame = +2 Query: 494 VFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE- 670 VFGV + +RE+S VP I+ +C + + G+ +++ G +Q L ++++ Sbjct: 644 VFGVKISVVTKRERS--KVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDAN 701 Query: 671 ----------------AALIKCYLASIPEPLTTFALYDE------LKDARVSIDDLKNIL 784 A +K Y +PEPL T LY L D + + ++L Sbjct: 702 NKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 761 Query: 785 KKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 + LP+ N +T F+ L RV+ K +NKM LA F P ++ Sbjct: 762 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 805
>Q13017:RHG05_HUMAN Rho GTPase-activating protein 5 - Homo sapiens (Human)| Length = 1499 Score = 63.5 bits (153), Expect = 2e-09 Identities = 45/160 (28%), Positives = 79/160 (49%), Gaps = 22/160 (13%) Frame = +2 Query: 488 SDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDR----KVLQQLV 655 S+ FG+P++ E K +PL + +C + + +GL E L++ G++ + +Q V Sbjct: 1254 SNYFGMPLQDLVTAE---KPIPLFVEKCVEFIEDTGLCTERLYRVSGNKTDQENIQKQFV 1310 Query: 656 SLYN------------EAALIKCYLASIPEPLTTFALYDELKDARVSIDD------LKNI 781 +N A +K + A +P+PL ++L+ EL +A D LK I Sbjct: 1311 QDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEI 1370 Query: 782 LKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEF 901 +KK VNY +V + L RVS++ +N M + L++ F Sbjct: 1371 VKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICF 1410
>P97393:RHG05_MOUSE Rho GTPase-activating protein 5 - Mus musculus (Mouse)| Length = 1501 Score = 62.4 bits (150), Expect = 4e-09 Identities = 42/160 (26%), Positives = 78/160 (48%), Gaps = 22/160 (13%) Frame = +2 Query: 488 SDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYN 667 S+ FG+P++ E K +PL + +C + + +GL E L++ G++ + ++ Sbjct: 1256 SNYFGMPLQDLVTAE---KPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFD 1312 Query: 668 E----------------AALIKCYLASIPEPLTTFALYDELKDARVSIDD------LKNI 781 + A +K + A +P+PL ++L+ EL +A D LK I Sbjct: 1313 QDHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERFHALKEI 1372 Query: 782 LKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEF 901 +KK VNY +V + L RVS+++ +N M + L++ F Sbjct: 1373 VKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICF 1412
>P11274:BCR_HUMAN Breakpoint cluster region protein - Homo sapiens (Human)| Length = 1271 Score = 62.4 bits (150), Expect = 4e-09 Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 24/165 (14%) Frame = +2 Query: 494 VFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE- 670 VFGV + +RE+S VP I+ +C + + G+ +++ G +Q L + ++ Sbjct: 1051 VFGVKIAVVTKRERS--KVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVN 1108 Query: 671 ----------------AALIKCYLASIPEPLTTFALYDELKDARVSIDD-------LKNI 781 A +K Y +PEPL T Y + +++ D + N+ Sbjct: 1109 NKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEG-IALSDPVAKESCMLNL 1167 Query: 782 LKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 L LP N +T F+ L RV+ K A+NKM LA F P ++ Sbjct: 1168 LLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLL 1212
>Q80YF9:TCGAP_MOUSE TC10/CDC42 GTPase-activating protein - Mus musculus (Mouse)| Length = 1305 Score = 62.0 bits (149), Expect = 6e-09 Identities = 46/172 (26%), Positives = 85/172 (49%), Gaps = 23/172 (13%) Frame = +2 Query: 470 QKGVASSDVFGVPVEATAQREQSGKAVPLILVRCAD----HLVISGL-------SNEYLF 616 Q+G+ VFG + SG+ VP +L C++ H V+ G+ SN Sbjct: 328 QRGILRQRVFGC--DLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRL 385 Query: 617 KSEGDRKVLQQLVS------LYNEAALIKCYLASIPEPLTTFALYDELKDA------RVS 760 + E D + + +L +++ ++L K Y +P PL T+ LY + +A Sbjct: 386 RHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEER 445 Query: 761 IDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 + + +++++LP +Y TLE++ L R++R SA M +R LA+ +AP ++ Sbjct: 446 LVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLL 497
>O14559:TCGAP_HUMAN TC10/CDC42 GTPase-activating protein - Homo sapiens (Human)| Length = 1287 Score = 62.0 bits (149), Expect = 6e-09 Identities = 46/172 (26%), Positives = 85/172 (49%), Gaps = 23/172 (13%) Frame = +2 Query: 470 QKGVASSDVFGVPVEATAQREQSGKAVPLILVRCAD----HLVISGL-------SNEYLF 616 Q+G+ VFG + SG+ VP +L C++ H V+ G+ SN Sbjct: 304 QRGILRQRVFGC--DLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRL 361 Query: 617 KSEGDRKVLQQLVS------LYNEAALIKCYLASIPEPLTTFALYDELKDA------RVS 760 + E D + + +L +++ ++L K Y +P PL T+ LY + +A Sbjct: 362 RHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEER 421 Query: 761 IDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 + + +++++LP +Y TLE++ L R++R SA M +R LA+ +AP ++ Sbjct: 422 LVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLL 473
>Q8C0D4:RHG12_MOUSE Rho GTPase-activating protein 12 - Mus musculus (Mouse)| Length = 838 Score = 62.0 bits (149), Expect = 6e-09 Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 22/178 (12%) Frame = +2 Query: 470 QKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQ 649 +KG VFG + QRE VP + C +H+ GL + +++ G+ V+Q+ Sbjct: 637 EKGYIKDQVFGSNLANLCQRENG--TVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQK 694 Query: 650 LVSLYNE-----------------AALIKCYLASIPEPLTTFALYDELKDA-----RVSI 763 L N +K + +PEPL TF +++ +A R + Sbjct: 695 LRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRV 754 Query: 764 DDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSG 937 +K+++++LP N T++ + L RV N+M +++A+ F P ++ + ++G Sbjct: 755 TAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETG 812
>Q8BYW1:RHG25_MOUSE Rho GTPase-activating protein 25 - Mus musculus (Mouse)| Length = 648 Score = 61.6 bits (148), Expect = 8e-09 Identities = 46/176 (26%), Positives = 77/176 (43%), Gaps = 31/176 (17%) Frame = +2 Query: 458 IERWQK------GVASSDVFGVPVEATAQREQS--GKAVPLILVRCADHLVISGLSNEYL 613 +E W K G S VFG ++ T EQ VP+++ +CA+ ++ G+S E + Sbjct: 139 MEEWVKFLRRVAGTPSGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGVSEEGI 198 Query: 614 FKSEGDRKVLQQL---------------VSLYNEAALIKCYLASIPEPLTTFALYDEL-- 742 F+ G +++QL ++ A+L+K YL +PEP+ ++ Y+ Sbjct: 199 FRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLL 258 Query: 743 ------KDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLA 892 D + +L L LP NY L ++ L + A+NKM LA Sbjct: 259 CGQLMNADEAKAQQELVKQLSTLPRDNYNLLSYICRFLHEIQLNCAVNKMSVDNLA 314
>Q6INE5:RHG19_XENLA Rho GTPase-activating protein 19 - Xenopus laevis (African clawed| frog) Length = 507 Score = 61.6 bits (148), Expect = 8e-09 Identities = 61/206 (29%), Positives = 87/206 (42%), Gaps = 36/206 (17%) Frame = +2 Query: 449 LNNIERWQKGVASSDVFGVPV--EATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKS 622 LN ++R +KG+ VFG P+ E AQ + + D+L L E LF+ Sbjct: 98 LNFLKRKEKGI----VFGAPLTEEGIAQ-----------IYQLIDYLH-KNLRTEGLFRI 141 Query: 623 EGDRKVLQQLVSLYNE----------------AALIKCYLASIPEPLTTFALY-DELKDA 751 G+ Q L L N A L+K +L +PEPL T Y LK A Sbjct: 142 PGNSIRQQNLKDLLNSGMDIDVESGEFHPNDVATLLKMFLGELPEPLLTHRHYIAHLKIA 201 Query: 752 RVSIDDLKN-----------------ILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDS 880 + + D K + LP+ N L+ + LL + +RK NKM + Sbjct: 202 NLMLFDAKGNRTGVPDKERQIEALQLLFLLLPSPNRNLLKLLLDLLYQTARKQDRNKMSA 261 Query: 881 RTLAVEFAPLIIWQQGDSGTDLRNHL 958 LA+ FAP IIW + + DL+ HL Sbjct: 262 HNLALMFAPHIIWPKNLTANDLQEHL 287
>Q8IWW6:RHG12_HUMAN Rho GTPase-activating protein 12 - Homo sapiens (Human)| Length = 846 Score = 61.6 bits (148), Expect = 8e-09 Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 22/178 (12%) Frame = +2 Query: 470 QKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQ 649 +KG VFG + QRE VP + C +H+ GL + +++ G+ V+Q+ Sbjct: 645 EKGYIKDQVFGSNLANLCQRENG--TVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQK 702 Query: 650 LVSLYNE-----------------AALIKCYLASIPEPLTTFALYDELKDA-----RVSI 763 L N +K + +PEPL TF +++ +A R + Sbjct: 703 LRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRV 762 Query: 764 DDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSG 937 +K+++++LP N T++ + L RV N+M +++A+ F P ++ + ++G Sbjct: 763 AAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETG 820
>Q9BE31:RHG12_MACFA Rho GTPase-activating protein 12 - Macaca fascicularis (Crab eating| macaque) (Cynomolgus monkey) Length = 847 Score = 61.2 bits (147), Expect = 1e-08 Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 22/178 (12%) Frame = +2 Query: 470 QKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQ 649 +KG VFG + QRE VP + C +H+ GL + +++ G+ V+Q+ Sbjct: 646 EKGYIKDQVFGSNLANLCQRENG--TVPKFVKLCIEHVEEYGLDVDGIYRVSGNLAVIQK 703 Query: 650 LVSLYNE-----------------AALIKCYLASIPEPLTTFALYDELKDA-----RVSI 763 L N +K + +PEPL TF +++ +A R + Sbjct: 704 LRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRV 763 Query: 764 DDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSG 937 +K+++++LP N T++ + L RV N+M +++A+ F P ++ + ++G Sbjct: 764 AAVKDLIRQLPKPNQDTMQILFRHLKRVVENGEKNRMTYQSIAIVFGPTLLKPEKETG 821
>Q9QY06:MYO9B_MOUSE Myosin-IXb - Mus musculus (Mouse)| Length = 2114 Score = 61.2 bits (147), Expect = 1e-08 Identities = 48/180 (26%), Positives = 88/180 (48%), Gaps = 23/180 (12%) Frame = +2 Query: 497 FGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEG----DRKVLQQLVS-- 658 FGV V++ + S VP++L + +H+ + GL E L++ G R++ Q L + Sbjct: 1656 FGVCVDSLTSDKAS---VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDP 1712 Query: 659 ---------LYNEAALIKCYLASIPEPLTTFALYD------ELKDARVSIDDLKNILKKL 793 ++ ++K +L +PEPL TFA Y EL + + + + +L L Sbjct: 1713 AAVKLEDFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLSAIYAVLDHL 1772 Query: 794 PNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIW--QQGDSGTDLRNHLRFT 967 P N+ +LE + L++V+ +N+M LA+ FAP ++ D T +++ L+ T Sbjct: 1773 PEANHTSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKIT 1832
>Q13459:MYO9B_HUMAN Myosin-IXb - Homo sapiens (Human)| Length = 2158 Score = 60.8 bits (146), Expect = 1e-08 Identities = 48/180 (26%), Positives = 89/180 (49%), Gaps = 23/180 (12%) Frame = +2 Query: 497 FGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEG----DRKVLQQLVS-- 658 FGV V++ + S VP++L + +H+ + GL E L++ G R++ Q L + Sbjct: 1698 FGVCVDSLTSDKAS---VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDP 1754 Query: 659 ---------LYNEAALIKCYLASIPEPLTTFALYD------ELKDARVSIDDLKNILKKL 793 ++ ++K +L +PEPL TFA Y EL + + + + +L+ L Sbjct: 1755 AAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHL 1814 Query: 794 PNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIW--QQGDSGTDLRNHLRFT 967 P N+ +LE + L++V+ +N+M LA+ FAP ++ D T +++ L+ T Sbjct: 1815 PEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKIT 1874
>Q6PAJ1:BCR_MOUSE Breakpoint cluster region protein - Mus musculus (Mouse)| Length = 1270 Score = 60.8 bits (146), Expect = 1e-08 Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 24/165 (14%) Frame = +2 Query: 494 VFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE- 670 VFGV + +RE+S VP I+ +C + + G+ +++ G +Q L + ++ Sbjct: 1050 VFGVKIAVVTKRERS--KVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVN 1107 Query: 671 ----------------AALIKCYLASIPEPLTTFALYDELKDARVSIDD-------LKNI 781 A +K Y +PEPL T Y + +++ D + N+ Sbjct: 1108 NKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEG-IALSDPVAKESCMLNL 1166 Query: 782 LKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 L LP N +T F+ L RV+ K +NKM LA F P ++ Sbjct: 1167 LLSLPEANLLTFLFLLDHLKRVAEKETVNKMSLHNLATVFGPTLL 1211
>Q63358:MYO9B_RAT Myosin-IXb - Rattus norvegicus (Rat)| Length = 1980 Score = 60.5 bits (145), Expect = 2e-08 Identities = 48/180 (26%), Positives = 88/180 (48%), Gaps = 23/180 (12%) Frame = +2 Query: 497 FGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEG----DRKVLQQLVS-- 658 FGV V++ + S VP++L + +H+ + GL E L++ G R++ Q L + Sbjct: 1658 FGVCVDSLTSDKAS---VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDP 1714 Query: 659 ---------LYNEAALIKCYLASIPEPLTTFALYD------ELKDARVSIDDLKNILKKL 793 ++ ++K +L +PEPL TFA Y EL + + + + +L L Sbjct: 1715 ATVKLEDFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLDHL 1774 Query: 794 PNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIW--QQGDSGTDLRNHLRFT 967 P N+ +LE + L++V+ +N+M LA+ FAP ++ D T +++ L+ T Sbjct: 1775 PEANHTSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKIT 1834
>Q9HF75:BEM2_ASHGO GTPase-activating protein BEM2 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 2071 Score = 59.7 bits (143), Expect = 3e-08 Identities = 52/188 (27%), Positives = 80/188 (42%), Gaps = 32/188 (17%) Frame = +2 Query: 473 KGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL 652 KG S+ +FGVPVE +RE G +P I+V+ D + + GL L++ G + L Sbjct: 1862 KGKTSNKIFGVPVEDVCERE--GALIPNIIVKLLDEIELRGLDEVGLYRVPGSVGSINAL 1919 Query: 653 VSLYNE---------------------AALIKCYLASIPEPLTTFALYDEL-------KD 748 + +++ A K YL +PE L T DE K+ Sbjct: 1920 KNAFDDEGAVHNTFTLEDDRWFEINTIAGCFKLYLRELPESLFTNEKVDEFVNIMTAYKN 1979 Query: 749 ARVSIDDLKN----ILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 V + +N +L LP NY L+ + L RV + N+MD+ LA+ F+ I Sbjct: 1980 HEVDLSQFQNGIKTLLSTLPVFNYHILKRLFLHLNRVHQHVENNRMDASNLAIVFSMSFI 2039 Query: 917 WQQGDSGT 940 Q + T Sbjct: 2040 NQDDLAST 2047
>P39960:BEM2_YEAST GTPase-activating protein BEM2/IPL2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 2167 Score = 59.3 bits (142), Expect = 4e-08 Identities = 45/183 (24%), Positives = 82/183 (44%), Gaps = 32/183 (17%) Frame = +2 Query: 473 KGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL 652 KG + +FGVP+E +RE + +P I+V+ + + + GL L++ G + L Sbjct: 1957 KGKTHNKIFGVPLEDVCERENT--LIPTIVVKLLEEIELRGLDEVGLYRIPGSIGSINAL 2014 Query: 653 VSLYNE---------------------AALIKCYLASIPEPLTTFALYDELKD------A 751 + ++E A K YL +P+ L + A+ ++ D A Sbjct: 2015 KNAFDEEGATDNSFTLEDDRWFEVNAIAGCFKMYLRELPDSLFSHAMVNDFTDLAIKYKA 2074 Query: 752 RVSIDD-----LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 +++ + +L+KLP Y TL+ + L +V + NKMD+ LA+ F+ I Sbjct: 2075 HAMVNEEYKRMMNELLQKLPTCYYQTLKRIVFHLNKVHQHVVNNKMDASNLAIVFSMSFI 2134 Query: 917 WQQ 925 Q+ Sbjct: 2135 NQE 2137
>P55194:3BP1_MOUSE SH3 domain-binding protein 1 - Mus musculus (Mouse)| Length = 601 Score = 57.4 bits (137), Expect = 1e-07 Identities = 44/173 (25%), Positives = 77/173 (44%), Gaps = 25/173 (14%) Frame = +2 Query: 488 SDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEY-LFKSEGDRKVLQQLVSL- 661 S V+GV + Q G+ + L + C L+ G+ E LF+ VL++L Sbjct: 191 SRVYGVSLRTHLQ--DLGRDIALPIEACVLLLLSEGMQEEEGLFRLAAGASVLKRLKQTM 248 Query: 662 --------------YNEAALIKCYLASIPEPLTTFALYDE------LKDARVSIDDLKNI 781 + A +K YL +PEPL T LYD+ LK+ ++ L ++ Sbjct: 249 ASDPHSLEEFCSGPHAVAGALKSYLRELPEPLMTSDLYDDWMRAASLKEPGARLEALHDV 308 Query: 782 LKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIW---QQGD 931 +LP N+ L ++ L ++ + +NKM +A+ P ++W ++GD Sbjct: 309 CSRLPQENFNNLRYLMKFLALLAEEQDVNKMTPSNIAIVLGPNLLWPPEKEGD 361
>P42331:RHG25_HUMAN Rho GTPase-activating protein 25 - Homo sapiens (Human)| Length = 638 Score = 55.5 bits (132), Expect = 5e-07 Identities = 40/158 (25%), Positives = 70/158 (44%), Gaps = 25/158 (15%) Frame = +2 Query: 494 VFGVPVEATAQREQS--GKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL----- 652 VFG ++ T EQ VP+++ +CA+ ++ G + E +F+ G +++QL Sbjct: 149 VFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFD 208 Query: 653 ----------VSLYNEAALIKCYLASIPEPLTTFALYDEL--------KDARVSIDDLKN 778 ++ A+L+K YL +PEP+ ++ Y+ D + +L Sbjct: 209 AGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMK 268 Query: 779 ILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLA 892 L LP NY L ++ L + A+NKM LA Sbjct: 269 QLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLA 306
>Q15311:RBP1_HUMAN RalA-binding protein 1 - Homo sapiens (Human)| Length = 655 Score = 54.7 bits (130), Expect = 9e-07 Identities = 35/162 (21%), Positives = 74/162 (45%), Gaps = 22/162 (13%) Frame = +2 Query: 494 VFGVPVEATAQREQ--SGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYN 667 +FG+P+ +R G +P + C D++ G+ E +++ G + + +L + Y+ Sbjct: 189 IFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD 248 Query: 668 E--------------AALIKCYLASIPEPLTTFALYDELKDA------RVSIDDLKNILK 787 A+L+K YL +PE L T L ++A + + + +LK Sbjct: 249 REESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQRLLK 308 Query: 788 KLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLI 913 +LP NY+ + ++ + V K KM+ + +++ +P + Sbjct: 309 ELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
>Q8WZ64:CEND1_HUMAN Centaurin-delta 1 - Homo sapiens (Human)| Length = 1704 Score = 54.7 bits (130), Expect = 9e-07 Identities = 41/172 (23%), Positives = 76/172 (44%), Gaps = 23/172 (13%) Frame = +2 Query: 500 GVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE--- 670 G A ++ S VP+I+ C + GL +Y+++ GD + +L+ + + Sbjct: 1112 GTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISELLESFKKDAR 1171 Query: 671 --------------AALIKCYLASIPEPLTTFALYDELKDARVSIDDLKNI------LKK 790 A++K +L+ I + L T LY A + DD + I ++ Sbjct: 1172 SFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERIKKYGAFIRS 1231 Query: 791 LPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDL 946 LP VN TL + L RV + S +N M++ LA+ F+ + +G + ++ Sbjct: 1232 LPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQTSEEV 1283
>O74360:RGA4_SCHPO Probable Rho-type GTPase-activating protein 4 - Schizosaccharomyces| pombe (Fission yeast) Length = 933 Score = 54.3 bits (129), Expect = 1e-06 Identities = 40/171 (23%), Positives = 77/171 (45%), Gaps = 20/171 (11%) Frame = +2 Query: 464 RWQKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVL 643 ++Q + S V+ + + Q + VP ++V C + + G+ E L++ G + Sbjct: 732 QYQSKKSESPVWALNPDDFDQNRLTLLRVPTLIVSCINFIESYGMDFEGLYRKSGATSQM 791 Query: 644 QQLVSLYNE--------------AALIKCYLASIPEPLTTFALYDELKDA------RVSI 763 +++V+L ++ K YL ++P P+ T+ Y A + + Sbjct: 792 KKIVALLRNEDTVLDPSEDISAVTSVFKQYLRNLPNPIITYDQYFPFITAANCASFQDKL 851 Query: 764 DDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 D ++K LP + L+ + L RV+ S N+M S+ LAV F+P +I Sbjct: 852 DGFIMVIKSLPPAHAEILQLIIRHLARVAAYSHANRMTSKNLAVVFSPTLI 902
>Q8N103:TAGAP_HUMAN T-cell activation Rho GTPase-activating protein - Homo sapiens| (Human) Length = 731 Score = 53.1 bits (126), Expect = 3e-06 Identities = 37/137 (27%), Positives = 64/137 (46%), Gaps = 20/137 (14%) Frame = +2 Query: 581 LVISGLSNEYLFKSEGDRKVLQQLVSLYNE--------------AALIKCYLASIPEPLT 718 L + G S E +F+ + K ++L N A + K +L SIP L Sbjct: 111 LCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERLPVHLLAVVFKDFLRSIPRKLL 170 Query: 719 TFALYDE------LKDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDS 880 + L++E ++D I+ LK + KLP N + L+ + +L +S+ S +N+MDS Sbjct: 171 SSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDS 230 Query: 881 RTLAVEFAPLIIWQQGD 931 LA+ P ++ + D Sbjct: 231 SNLAICIGPNMLTLEND 247
>Q96P48:CEND2_HUMAN Centaurin-delta 2 - Homo sapiens (Human)| Length = 1210 Score = 52.8 bits (125), Expect = 4e-06 Identities = 46/176 (26%), Positives = 81/176 (46%), Gaps = 30/176 (17%) Frame = +2 Query: 518 TAQREQSGKA-VPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLV-SLYNEA------ 673 T +Q G + +P+I+ RC D++ GL++E +++ G Q+L+ SL +A Sbjct: 719 TLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLK 778 Query: 674 ----------ALIKCYLASIPEPLTTFALY------DELKDARVSIDDLKNILKKLPNVN 805 + +K +L +P+ L T A E++D + + +L +LP VN Sbjct: 779 EGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVN 838 Query: 806 YMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII------WQQGDSGTDLRNH 955 T++ + S L V S N+M+ LA+ F P + ++ G DL NH Sbjct: 839 RATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKAGRVVEDLINH 894
>Q6REY9:RHG20_RAT Rho GTPase-activating protein 20 - Rattus norvegicus (Rat)| Length = 1182 Score = 52.4 bits (124), Expect = 5e-06 Identities = 33/112 (29%), Positives = 59/112 (52%), Gaps = 6/112 (5%) Frame = +2 Query: 656 SLYNEAALIKCYLASIPEPLTTFALYD------ELKDARVSIDDLKNILKKLPNVNYMTL 817 S++ A+++K +L +IPE + + LYD + + I+ ++ +L +LP N + L Sbjct: 426 SIFVIASVLKDFLRNIPESIFSSDLYDHWVCVMDQGNDEEKINTIQRLLDQLPRANVVFL 485 Query: 818 EFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLRNHLRFTLK 973 ++ +L + + S N+M + LAV AP I+W S +L N FT K Sbjct: 486 RYLFGVLHNIEQHSLSNQMTAFNLAVCIAPSILWPPASSSPELEN--EFTKK 535
>Q5F3G0:RHG19_CHICK Rho GTPase-activating protein 19 - Gallus gallus (Chicken)| Length = 495 Score = 52.4 bits (124), Expect = 5e-06 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 18/114 (15%) Frame = +2 Query: 671 AALIKCYLASIPEPLTT------------FALYDE------LKDARVSIDDLKNILKKLP 796 A L+K +L +PEPL T L+DE D I+ L+ + LP Sbjct: 173 ATLLKMFLGELPEPLLTHKHFHAHLKIADLTLFDEKGNKTSTPDKERQIEALQLLFLILP 232 Query: 797 NVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLRNHL 958 N L+ + LL + ++K NKM + LA+ FAP I+W + + DL+ ++ Sbjct: 233 APNRSLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHILWPRNVTANDLQENI 286
>Q10164:RGA2_SCHPO Probable Rho-type GTPase-activating protein 2 - Schizosaccharomyces| pombe (Fission yeast) Length = 1275 Score = 52.4 bits (124), Expect = 5e-06 Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 29/174 (16%) Frame = +2 Query: 479 VASSDVFGVP----VEATAQREQSGKAVPLILVRCADHLVISGLSNEY-LFKSEGDRKVL 643 V S +FG+P V + Q SG +P+++ RC ++L E +++ G + Sbjct: 1057 VRKSGIFGLPLNEAVNISTQFNDSG--LPIVVYRCIEYLESCRAEKEEGIYRLSGSASTI 1114 Query: 644 QQLVSLYNE------------------AALIKCYLASIPEPLTT------FALYDELKDA 751 + L +NE A L+K YL ++P L F L + + Sbjct: 1115 KHLKEQFNEGVDYDLLSSDEEFDVHVIAGLLKLYLRNLPTNLLDTSMHKLFELLPNVPND 1174 Query: 752 RVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLI 913 ++ +L +++ KLP N+ L+ + L R+ +NKM+ R + + F+P + Sbjct: 1175 SAALGELCDVISKLPPENFALLDSLLHHLRRIIAFEKVNKMNIRNVCIVFSPTL 1228
>Q6IFT4:RHG20_MOUSE Rho GTPase-activating protein 20 - Mus musculus (Mouse)| Length = 1182 Score = 51.6 bits (122), Expect = 8e-06 Identities = 33/112 (29%), Positives = 59/112 (52%), Gaps = 6/112 (5%) Frame = +2 Query: 656 SLYNEAALIKCYLASIPEPLTTFALYD------ELKDARVSIDDLKNILKKLPNVNYMTL 817 S++ A+++K +L +IPE + + LYD + + I+ ++ +L +LP N + L Sbjct: 426 SIFVIASVLKDFLRNIPESIFSSDLYDHWVCVMDQGNDEEKINIIQRLLDQLPRANVVFL 485 Query: 818 EFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLRNHLRFTLK 973 ++ +L + + S N+M + LAV AP I+W S +L N FT K Sbjct: 486 RYLFGVLHNIEQHSLSNQMTAFNLAVCIAPSILWPPASSSPELEN--EFTKK 535
>P46941:TG325_CAEEL WW domain-containing protein tag-325 - Caenorhabditis elegans| Length = 837 Score = 51.2 bits (121), Expect = 1e-05 Identities = 48/203 (23%), Positives = 89/203 (43%), Gaps = 24/203 (11%) Frame = +2 Query: 470 QKGVASSD-VFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQ 646 +KG+ + VFG + A Q E S VP + + + GL + +++ G+ +Q Sbjct: 598 EKGIYKPEPVFGSTLSAICQHENS--LVPKFIRVITEVIESKGLETDGIYRVSGNLSAVQ 655 Query: 647 QL---------VSLYNEAAL------IKCYLASIPEPLTTFALYDE------LKDARVSI 763 ++ +L +E + +K + + +PL +L+ E + +A Sbjct: 656 KIRCQADQDNYKALVSEEDIHVLTGALKLFFRELTDPLFPISLHKEYTSAMQMPNATTRF 715 Query: 764 DDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTD 943 + +L +LPN N TL+ + L RV+ S+ N+M LA+ F P ++ GD + Sbjct: 716 KKFEELLSRLPNENRETLKMLLRHLNRVASHSSQNRMQQHNLAIVFGP-TLFHNGDGAVN 774 Query: 944 L--RNHLRFTLKPPPKIVDTTST 1006 L +N P K +T +T Sbjct: 775 LATKNKKAGKKAKPSKKEETQAT 797
>Q8BZ05:CEND1_MOUSE Centaurin-delta 1 - Mus musculus (Mouse)| Length = 1703 Score = 51.2 bits (121), Expect = 1e-05 Identities = 35/156 (22%), Positives = 71/156 (45%), Gaps = 23/156 (14%) Frame = +2 Query: 548 VPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNEAA----------------- 676 VP+I+ C + GL +Y+++ +GD + +L+ + + A Sbjct: 1126 VPIIVNSCIAFVTQYGLGCKYIYQKDGDPLHISELLESFKKDARSVKLRAGKHQLEDVTG 1185 Query: 677 LIKCYLASIPEPLTTFALYD------ELKDARVSIDDLKNILKKLPNVNYMTLEFVTSLL 838 ++K +L+ I + L T LY + +D + + ++ LP VN TL + L Sbjct: 1186 VLKSFLSDIDDALLTKELYPYWVSALDTQDEKERTSKYRAFIRSLPGVNRATLAALIEHL 1245 Query: 839 LRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDL 946 RV + S +N M++ LA+ F+ + +G + ++ Sbjct: 1246 YRVQKCSEINHMNAHNLAMVFSSCLFQTKGQTSEEV 1281
>Q9P2F6:RHG20_HUMAN Rho GTPase-activating protein 20 - Homo sapiens (Human)| Length = 1191 Score = 50.1 bits (118), Expect = 2e-05 Identities = 32/112 (28%), Positives = 59/112 (52%), Gaps = 6/112 (5%) Frame = +2 Query: 656 SLYNEAALIKCYLASIPEPLTTFALYD------ELKDARVSIDDLKNILKKLPNVNYMTL 817 S++ A+++K +L +IP + + LYD + + I+ ++ +L +LP N + L Sbjct: 426 SIFVIASVLKDFLRNIPGSIFSSDLYDHWVSVMDQGNDEEKINTVQRLLDQLPRANVVLL 485 Query: 818 EFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLRNHLRFTLK 973 ++ +L + + S+ N+M + LAV AP I+W S +L N FT K Sbjct: 486 RYLFGVLHNIEQHSSSNQMTAFNLAVCVAPSILWPPASSSPELEN--EFTKK 535
>Q9PT60:RBP1A_XENLA RalA-binding protein 1-A - Xenopus laevis (African clawed frog)| Length = 655 Score = 50.1 bits (118), Expect = 2e-05 Identities = 35/162 (21%), Positives = 73/162 (45%), Gaps = 22/162 (13%) Frame = +2 Query: 494 VFGVPVEATAQREQ--SGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYN 667 VFG+P+ A+R G +PL+ C D + G+ E +++ G + + +L + Y+ Sbjct: 184 VFGIPLIEAAERTMIYDGIRLPLVFRECIDFIEQHGMKCEGIYRVSGIKSKVDELKAAYD 243 Query: 668 E--------------AALIKCYLASIPEPLTTFALYDELKDA------RVSIDDLKNILK 787 A+L+K YL +PE + T L ++A + + + +LK Sbjct: 244 REESPNLEDYEPYTVASLLKQYLRELPENVLTKDLMPRFEEACGKTTEGERLQECQRLLK 303 Query: 788 KLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLI 913 +LP N+ ++ + V + KM+ + +++ +P + Sbjct: 304 ELPECNFCLTSWLVVHMDHVIEQELETKMNIQNISIVLSPTV 345
>Q6PGG2:GMIP_MOUSE GEM-interacting protein - Mus musculus (Mouse)| Length = 971 Score = 50.1 bits (118), Expect = 2e-05 Identities = 35/156 (22%), Positives = 66/156 (42%), Gaps = 33/156 (21%) Frame = +2 Query: 548 VPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNEA---------------ALI 682 VP ++ RC + L + +++ G R +++L + +++ Sbjct: 563 VPFVITRCTAEIEHRALGLQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDITSVL 622 Query: 683 KCYLASIPEPLTTFALYDELKDARVSI-----DD-------------LKNILKKLPNVNY 808 K +L + +P+ F LYD ++ DD LK +L +LP+ NY Sbjct: 623 KRFLQELTDPVVPFHLYDAFISLAKTLHADPGDDPGTPNPSPEIIRSLKTLLVQLPDSNY 682 Query: 809 MTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 TL + + L RV+ + NKM + L + F P ++ Sbjct: 683 STLRHLVAHLFRVAARFEENKMSANNLGIVFGPTLL 718
>Q8BRH3:RHG19_MOUSE Rho GTPase-activating protein 19 - Mus musculus (Mouse)| Length = 494 Score = 49.7 bits (117), Expect = 3e-05 Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 18/114 (15%) Frame = +2 Query: 671 AALIKCYLASIPEPLTTFALYD------------------ELKDARVSIDDLKNILKKLP 796 A L+K +L +PEPL T + + D I+ L+ + LP Sbjct: 177 ATLLKMFLGELPEPLLTHKHFHVHLKIADLMQFDDKGNKTNIPDKERQIEALQLLFLILP 236 Query: 797 NVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLRNHL 958 N L+ + LL + ++K NKM + LA+ FAP ++W + + DL+ ++ Sbjct: 237 PANRNLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHVLWPKNVTANDLQENI 290
>Q9VDG2:RLIP_DROME RalA-binding protein 1 - Drosophila melanogaster (Fruit fly)| Length = 625 Score = 49.3 bits (116), Expect = 4e-05 Identities = 43/163 (26%), Positives = 75/163 (46%), Gaps = 23/163 (14%) Frame = +2 Query: 494 VFGVPVEATAQREQ--SGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYN 667 VFGV V +R + G +PL++ C D L L E ++K E + L LYN Sbjct: 186 VFGVSVSLATERSRCHDGVDIPLVVRDCIDFLQ-DHLKCEQIYKIEPIKTRLMHFKRLYN 244 Query: 668 E---------------AALIKCYLASIPEPLTTFALYDELKDA----RVSID--DLKNIL 784 +L+K +L +PEPL T L ++ +V+ +L+ +L Sbjct: 245 NREHDSAVDELNLPTACSLLKLFLRELPEPLLTTDLVARFEEVASHPKVTTQQAELQQLL 304 Query: 785 KKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLI 913 ++LP N L +V V ++ NK+++++LA+ +P + Sbjct: 305 EQLPKCNRTLLAWVLLHFDAVIQQERHNKLNAQSLAMLLSPTL 347
>P38339:RGD1_YEAST RHO GTPase-activating protein RGD1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 666 Score = 49.3 bits (116), Expect = 4e-05 Identities = 43/178 (24%), Positives = 74/178 (41%), Gaps = 28/178 (15%) Frame = +2 Query: 497 FGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVS------ 658 FGVP+E+ + EQ VP I+ +C + GL E +++ + + +L Sbjct: 470 FGVPLESLIEFEQD--MVPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDP 527 Query: 659 ----------------LYNEAALIKCYLASIPEPLTTFALYDELK------DARVSIDDL 772 +Y +L+K + AS+P+ + AL E+K D + + Sbjct: 528 ANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPTTRKNFM 587 Query: 773 KNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDL 946 ++ LP+ Y TL + L RV A N+M+ R L + + P I D D+ Sbjct: 588 HGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAPANPDDANDV 645
>Q9P107:GMIP_HUMAN GEM-interacting protein - Homo sapiens (Human)| Length = 970 Score = 49.3 bits (116), Expect = 4e-05 Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 33/156 (21%) Frame = +2 Query: 548 VPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE---------------AALI 682 VP ++ +C + L + +++ G R +++L + ++++ Sbjct: 564 VPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDVSSVL 623 Query: 683 KCYLASIPEPLTTFALYDELKDARVSI-----DD-------------LKNILKKLPNVNY 808 K +L + EP+ F LYD ++ DD LK +L +LP+ NY Sbjct: 624 KRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPDVIRSLKTLLVQLPDSNY 683 Query: 809 MTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 TL + + L RV+ + NKM + L + F P ++ Sbjct: 684 NTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLL 719
>Q9WVM1:RGAP1_MOUSE Rac GTPase-activating protein 1 - Mus musculus (Mouse)| Length = 628 Score = 48.9 bits (115), Expect = 5e-05 Identities = 43/150 (28%), Positives = 68/150 (45%), Gaps = 22/150 (14%) Frame = +2 Query: 533 QSGKAVPLILVRCADHLVISGLSNEYLFKSEG-DRKV---------------LQQLVSLY 664 Q+ +P I+V C + + GL+ L++ G DR V L ++ ++ Sbjct: 358 QASPMIPAIVVSCVNEIEQRGLTEAGLYRISGCDRTVKELKEKFLKVKTVPLLSKVDDIH 417 Query: 665 NEAALIKCYLASIPEPLTTFALYDELKDARVSIDD------LKNILKKLPNVNYMTLEFV 826 +L+K +L ++ EPL TF L +A D+ + + +LP N TL F+ Sbjct: 418 VICSLLKDFLRNLKEPLLTFWLSKAFMEAAEITDEDNSTAAMYQAVSELPQANRDTLAFL 477 Query: 827 TSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 L RVS +S KMD LA F P I+ Sbjct: 478 MIHLQRVS-QSPDTKMDIANLAKVFGPTIV 506
>Q8WWN8:CEND3_HUMAN Centaurin-delta 3 - Homo sapiens (Human)| Length = 1544 Score = 48.9 bits (115), Expect = 5e-05 Identities = 39/165 (23%), Positives = 73/165 (44%), Gaps = 23/165 (13%) Frame = +2 Query: 524 QREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNEAA--------- 676 +++ S +P+I+ C + GL E +++ G R +L++ + A Sbjct: 911 EQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGE 970 Query: 677 --------LIKCYLASIPEPLTTFALYD------ELKDARVSIDDLKNILKKLPNVNYMT 814 +K + + +P+T+ L EL ++ K+++ LP VN T Sbjct: 971 HFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRRT 1030 Query: 815 LEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLR 949 L + L RV + +ALN+M +R LA+ FAP + G ++R Sbjct: 1031 LATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGRGEHEVR 1075
>P26450:P85A_MOUSE Phosphatidylinositol 3-kinase regulatory subunit alpha - Mus| musculus (Mouse) Length = 724 Score = 48.5 bits (114), Expect = 7e-05 Identities = 41/185 (22%), Positives = 90/185 (48%), Gaps = 23/185 (12%) Frame = +2 Query: 473 KGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGD------R 634 K A ++ +P+ A++ P +L++ + + GL L++++ R Sbjct: 103 KTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELR 162 Query: 635 KVLQ--------QLVSLYNEAALIKCYLASIPEPLTTFALYDE---LKDARVSIDDLKNI 781 ++L +++ ++ A K YLA +P P+ A+Y+E L S +D + Sbjct: 163 QLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQL 222 Query: 782 LKKL------PNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTD 943 LKKL P+ ++TL+++ ++S+ S+ N +++R L+ F+P ++++ + +D Sbjct: 223 LKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSP-VLFRFPAASSD 281 Query: 944 LRNHL 958 HL Sbjct: 282 NTEHL 286
>Q8R5G7:CEND3_MOUSE Centaurin-delta 3 - Mus musculus (Mouse)| Length = 1538 Score = 48.5 bits (114), Expect = 7e-05 Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 23/165 (13%) Frame = +2 Query: 524 QREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNEAA--------- 676 +++ S +P+I+ C + GL E +++ G R +L++ + A Sbjct: 907 EQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPRE 966 Query: 677 --------LIKCYLASIPEPLTTFALYD------ELKDARVSIDDLKNILKKLPNVNYMT 814 +K + + +P+T+ L EL ++ K ++ LP VN T Sbjct: 967 HFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELSQKNQRLEKYKEVISCLPRVNRRT 1026 Query: 815 LEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLR 949 L + L RV + ++LN+M +R LA+ FAP + G ++R Sbjct: 1027 LATLIGHLYRVQKCASLNQMCTRNLALLFAPSVFQTDGRGEHEVR 1071
>Q14CB8:RHG19_HUMAN Rho GTPase-activating protein 19 - Homo sapiens (Human)| Length = 494 Score = 48.1 bits (113), Expect = 9e-05 Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 18/114 (15%) Frame = +2 Query: 671 AALIKCYLASIPEPLTTFALYD------------------ELKDARVSIDDLKNILKKLP 796 A L+K +L +PEPL T ++ + D I+ L+ + LP Sbjct: 177 ATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILP 236 Query: 797 NVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLRNHL 958 N L+ + LL + ++K NKM + LA+ FAP ++W + + DL+ ++ Sbjct: 237 PPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENI 290
>Q99J31:OPHN1_MOUSE Oligophrenin 1 - Mus musculus (Mouse)| Length = 802 Score = 48.1 bits (113), Expect = 9e-05 Identities = 46/193 (23%), Positives = 80/193 (41%), Gaps = 27/193 (13%) Frame = +2 Query: 455 NIERWQKGVASSD-VFGVPVEATAQREQSGKAVPLILVR-CADHLVISGLSNEYLFKSEG 628 N W + + + ++ P+ T Q E V VR C + + G+ E L+++ G Sbjct: 355 NRRLWMEAMDGKEPIYHTPI--TKQEEMELNEVGFKFVRKCINFIETKGIKTEGLYRTVG 412 Query: 629 DRKVLQQL------------VSLYNE-------AALIKCYLASIPEPLTTFALYDELKDA 751 +Q+L V +N + +K YL ++ EP+ T+ L+ EL A Sbjct: 413 SNIQVQKLLYAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYKLHKELVSA 472 Query: 752 RVS------IDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLI 913 S + + +++ KLP N LE + L+ V S N M + V F P + Sbjct: 473 AKSDNLDYRLGAIHSLVYKLPEKNREMLELLIKHLVNVCEHSKENLMTPSNMGVIFGPTL 532 Query: 914 IWQQGDSGTDLRN 952 + Q D+ + N Sbjct: 533 MRAQEDTVAAMMN 545
>O94466:RGA7_SCHPO Probable Rho-GTPase-activating protein 7 - Schizosaccharomyces pombe| (Fission yeast) Length = 695 Score = 47.8 bits (112), Expect = 1e-04 Identities = 41/168 (24%), Positives = 75/168 (44%), Gaps = 25/168 (14%) Frame = +2 Query: 494 VFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFK------------SEGDRK 637 +FG ++A RE S +P I+++C + GL+ + +++ S+ + Sbjct: 503 LFGARLDAIILREHSN--IPNIVMQCTSQVENFGLNLQGIYRVPSSSARVNMLRSQFENN 560 Query: 638 VLQQLVS-------LYNEAALIKCYLASIPEPLTT------FALYDELKDARVSIDDLKN 778 L QL + ++ A L+K + + EPL F ++D D + Sbjct: 561 PLLQLHTPEDYENDVHAVADLLKIFFRELREPLIPDNHQRDFIDAGNVEDESRRRDAVHR 620 Query: 779 ILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQ 922 + LP+ NY T+ +T L ++ S +NKM + LA+ + P II Q Sbjct: 621 AINDLPDANYSTIRHLTIHLAKIKENSDVNKMSTNNLAIIWGPTIIKQ 668
>O14014:RGA3_SCHPO Probable Rho-type GTPase-activating protein 3 - Schizosaccharomyces| pombe (Fission yeast) Length = 969 Score = 47.8 bits (112), Expect = 1e-04 Identities = 37/165 (22%), Positives = 72/165 (43%), Gaps = 21/165 (12%) Frame = +2 Query: 485 SSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLY 664 S +FG +E + E G +P ++ C + GL E +++ G ++ LV + Sbjct: 774 SPTMFGRSLENQLKIE--GSVLPQVIAMCVSCVDAHGLEVEGIYRISGSASQVRVLVDEF 831 Query: 665 NEAAL---------------IKCYLASIPEPLTTFALYDELKDA------RVSIDDLKNI 781 ++ +K YL +PEP+ Y+EL +A I+ + + Sbjct: 832 ENGSIRMEHLTSDLFACTSVLKTYLHRLPEPVIPGTQYEELLEAEKIEKEEEKIERVVEV 891 Query: 782 LKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 +K L + F+ + L RV + + N M+S+ ++ FAP ++ Sbjct: 892 MKTLHPAHLSVFRFLIAHLGRVCKHAEKNLMNSKNVSTVFAPTLM 936
>Q7Z6B7:SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating protein 1 - Homo sapiens (Human)| Length = 1085 Score = 47.4 bits (111), Expect = 1e-04 Identities = 49/232 (21%), Positives = 89/232 (38%), Gaps = 24/232 (10%) Frame = +2 Query: 530 EQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE------------- 670 + SG+ +PLI+ C + + GL ++ +F+ G + + + + + Sbjct: 513 KDSGQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENPLADDQSNHD 572 Query: 671 ----AALIKCYLASIPEPLTTFALYDELKDARVSIDDL-------KNILKKLPNVNYMTL 817 A ++K Y + PL +++L + ID+L + +L LP + + Sbjct: 573 INSVAGVLKLYFRGLENPLFPKERFNDLISC-IRIDNLYERALHIRKLLLTLPRSVLIVM 631 Query: 818 EFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLRNHLRFTLKPPPKIVDT 997 ++ + L +S+ S N MD LA+ F P TL P P+I Sbjct: 632 RYLFAFLNHLSQYSDENMMDPYNLAICFGP-------------------TLMPVPEI--- 669 Query: 998 TSTITWDLLDEDDVDASSQIPLDDASPPDYGAIEVIQCLIEHHNPIFTDANE 1153 +D V + + E+I+ +I HH IF DA E Sbjct: 670 ----------QDQVSCQAHVN------------EIIKTIIIHHETIFPDAKE 699
>O43182:RHG06_HUMAN Rho GTPase-activating protein 6 - Homo sapiens (Human)| Length = 974 Score = 47.4 bits (111), Expect = 1e-04 Identities = 56/229 (24%), Positives = 97/229 (42%), Gaps = 41/229 (17%) Frame = +2 Query: 503 VPVEATAQREQSG----------KAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL 652 +P EA +++E++ + VP ++ C HL GL +F+ +K ++QL Sbjct: 385 LPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQL 444 Query: 653 ---------VSLYNE------AALIKCYLASIPEPLTTFALYDE-----LKDARVSIDDL 772 VSL E AAL+K +L +P+PL T LY L + + L Sbjct: 445 REEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTL 504 Query: 773 KNILKKLPNVNYMTLEFVTSLLLRVSRKS-----------ALNKMDSRTLAVEFAPLIIW 919 + ++ LP N TL + L V+R + NKM S LA F P ++ Sbjct: 505 QLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLH 564 Query: 920 QQGDSGTDLRNHLRFTLKPPPKIVDTTSTITWDLLDEDDVDASSQIPLD 1066 +Q S + F+++ + ++T+ I ++ +A +P D Sbjct: 565 KQKSSDKE------FSVQSSARAEESTAIIAVVQKMIENYEALFMVPPD 607
>Q7YQL5:OPHN1_PONPY Oligophrenin 1 - Pongo pygmaeus (Orangutan)| Length = 802 Score = 47.4 bits (111), Expect = 1e-04 Identities = 44/193 (22%), Positives = 82/193 (42%), Gaps = 27/193 (13%) Frame = +2 Query: 455 NIERWQKGVASSD-VFGVPVEATAQREQSGKAVPLILVR-CADHLVISGLSNEYLFKSEG 628 N W + + + ++ P+ T Q+E V VR C + + G+ E L+++ G Sbjct: 355 NRRLWMEAMDGKEPIYHSPI--TKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVG 412 Query: 629 DRKVLQQLVSLYNE-------------------AALIKCYLASIPEPLTTFALYDELKDA 751 +Q+L++ + + + +K YL ++ EP+ T+ L+ EL A Sbjct: 413 SNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSA 472 Query: 752 RVS------IDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLI 913 S + + +++ KLP N LE + L+ V S N M + V F P + Sbjct: 473 AKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTL 532 Query: 914 IWQQGDSGTDLRN 952 + Q D+ + N Sbjct: 533 MRAQEDTVAAMMN 545
>Q7YQL6:OPHN1_PANTR Oligophrenin 1 - Pan troglodytes (Chimpanzee)| Length = 802 Score = 47.4 bits (111), Expect = 1e-04 Identities = 44/193 (22%), Positives = 82/193 (42%), Gaps = 27/193 (13%) Frame = +2 Query: 455 NIERWQKGVASSD-VFGVPVEATAQREQSGKAVPLILVR-CADHLVISGLSNEYLFKSEG 628 N W + + + ++ P+ T Q+E V VR C + + G+ E L+++ G Sbjct: 355 NRRLWMEAMDGKEPIYHSPI--TKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVG 412 Query: 629 DRKVLQQLVSLYNE-------------------AALIKCYLASIPEPLTTFALYDELKDA 751 +Q+L++ + + + +K YL ++ EP+ T+ L+ EL A Sbjct: 413 SNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSA 472 Query: 752 RVS------IDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLI 913 S + + +++ KLP N LE + L+ V S N M + V F P + Sbjct: 473 AKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTL 532 Query: 914 IWQQGDSGTDLRN 952 + Q D+ + N Sbjct: 533 MRAQEDTVAAMMN 545
>O60890:OPHN1_HUMAN Oligophrenin 1 - Homo sapiens (Human)| Length = 802 Score = 47.4 bits (111), Expect = 1e-04 Identities = 44/193 (22%), Positives = 82/193 (42%), Gaps = 27/193 (13%) Frame = +2 Query: 455 NIERWQKGVASSD-VFGVPVEATAQREQSGKAVPLILVR-CADHLVISGLSNEYLFKSEG 628 N W + + + ++ P+ T Q+E V VR C + + G+ E L+++ G Sbjct: 355 NRRLWMEAMDGKEPIYHSPI--TKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVG 412 Query: 629 DRKVLQQLVSLYNE-------------------AALIKCYLASIPEPLTTFALYDELKDA 751 +Q+L++ + + + +K YL ++ EP+ T+ L+ EL A Sbjct: 413 SNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSA 472 Query: 752 RVS------IDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLI 913 S + + +++ KLP N LE + L+ V S N M + V F P + Sbjct: 473 AKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTL 532 Query: 914 IWQQGDSGTDLRN 952 + Q D+ + N Sbjct: 533 MRAQEDTVAAMMN 545
>Q9NYF5:CE005_HUMAN Uncharacterized protein C5orf5 - Homo sapiens (Human)| Length = 915 Score = 47.4 bits (111), Expect = 1e-04 Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 23/166 (13%) Frame = +2 Query: 479 VASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVI-SGLSNEYLFKSEGDRKVLQQL- 652 V ++ +FG+P++ Q VP I+ D++ GL + LF+ G+ + ++ L Sbjct: 15 VLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLR 74 Query: 653 --------VSLYNEA------ALIKCYLASIPEPLTTFALYDELKDARVSIDD------- 769 V L EA +L++ +L +PEP+ +L+ L ++ Sbjct: 75 QRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRK 134 Query: 770 LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAP 907 L+ +L++LP VNY L+F+ L V+ + +LA F P Sbjct: 135 LRFLLQQLPPVNYSLLKFLCRFLANVASHHE-EIWSANSLAAVFGP 179
>Q8K2H3:CE005_MOUSE Uncharacterized protein C5orf5 homolog - Mus musculus (Mouse)| Length = 851 Score = 47.0 bits (110), Expect = 2e-04 Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 23/164 (14%) Frame = +2 Query: 485 SSDVFGVPVEATAQREQSGKAVPLILVRCADHLVI-SGLSNEYLFKSEGDRKVLQQL--- 652 +S +FG+P++ Q VP I+ D++ GL + LF+ G+ + ++ L Sbjct: 17 ASKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQR 76 Query: 653 ------VSLYNEA------ALIKCYLASIPEPLTTFALYDELKDARVSIDD-------LK 775 V L EA +L++ +L +PEP+ +L+ L ++ L+ Sbjct: 77 YDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLLQLSQDYNNEDEFGRKLR 136 Query: 776 NILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAP 907 +L++LP VNY L+F+ L V+ + +LA F P Sbjct: 137 FLLQQLPPVNYSLLKFLCRFLANVASHHE-EIWSANSLAAVFGP 179
>Q8K0Q5:RHG18_MOUSE Rho GTPase-activating protein 18 - Mus musculus (Mouse)| Length = 663 Score = 46.6 bits (109), Expect = 3e-04 Identities = 39/166 (23%), Positives = 69/166 (41%), Gaps = 26/166 (15%) Frame = +2 Query: 488 SDVFGVPVEATAQREQS---GKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL-- 652 S +FG+P+ +++Q G +PLI + + L E L + G ++ L Sbjct: 319 SGLFGIPLTILLEQDQRKVPGTRIPLIFQKLISRIEEGSLETEGLLRIPGAAMRIKNLCQ 378 Query: 653 ---------------VSLYNEAALIKCYLASIPEPLTT------FALYDELKDARVSIDD 769 V ++ A+L+K +L +P+PL + F L + + Sbjct: 379 ELEAKFYEGTFNWESVKQHDAASLLKLFLRELPQPLLSMEYLKAFQAVQNLPTRKEQLQA 438 Query: 770 LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAP 907 L ++ LP+ N TL+ + L RV NKM + +A+ AP Sbjct: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTAGNVAMVMAP 484
>O54834:RHG06_MOUSE Rho GTPase-activating protein 6 - Mus musculus (Mouse)| Length = 987 Score = 46.6 bits (109), Expect = 3e-04 Identities = 47/185 (25%), Positives = 79/185 (42%), Gaps = 41/185 (22%) Frame = +2 Query: 503 VPVEATAQREQSG----------KAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL 652 +P EA +++E++ + VP ++ C HL GL +F+ +K ++QL Sbjct: 387 LPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQL 446 Query: 653 V---------------SLYNEAALIKCYLASIPEPLTTFALYDE-----LKDARVSIDDL 772 S+++ AAL+K +L +P+PL T LY L + + L Sbjct: 447 REEFDRGVDVCLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTL 506 Query: 773 KNILKKLPNVNYMTLEFVTSLLLRVSRKS-----------ALNKMDSRTLAVEFAPLIIW 919 + ++ LP N TL + L V+R + NKM S LA F P ++ Sbjct: 507 QLLIYLLPPCNCDTLHRLLQFLSIVARHADDNVSKDGQEVTGNKMTSLNLATIFGPNLLH 566 Query: 920 QQGDS 934 +Q S Sbjct: 567 KQKSS 571
>P98171:RHG04_HUMAN Rho GTPase-activating protein 4 - Homo sapiens (Human)| Length = 946 Score = 46.6 bits (109), Expect = 3e-04 Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 23/164 (14%) Frame = +2 Query: 494 VFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE- 670 +FG +E Q SG+ VPL++ C + ++GL +E +F+ G + + ++ + Sbjct: 504 LFGGDMEKFIQ--SSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERG 561 Query: 671 ----------------AALIKCYLASIPEPLTTFALY------DELKDARVSIDDLKNIL 784 A ++K Y S+ PL L+ EL+ ++ + +L Sbjct: 562 EDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLL 621 Query: 785 KKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 +LP + L ++ + L +++ S N MD LAV F P ++ Sbjct: 622 WRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGPTLL 665
>P39083:RGA1_YEAST Rho-type GTPase-activating protein 1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1007 Score = 46.6 bits (109), Expect = 3e-04 Identities = 42/193 (21%), Positives = 82/193 (42%), Gaps = 50/193 (25%) Frame = +2 Query: 488 SDVFGVPVEATAQREQSGKAVPLILVRCADHLVIS--GLSNEYLFKSEGDRKVLQQLVSL 661 S+++G + A E + +P+IL C D + + +E +++ G + V++++ Sbjct: 786 SNLYGSSLVARCNYENN--EIPMILSVCIDFIESDEENMRSEGIYRKSGSQLVIEEIEKQ 843 Query: 662 YNE---------------------AALIKCYLASIPEPLTTFALYDELK----------- 745 ++ ++K YL +P P+ TF +Y+ L Sbjct: 844 FSAWKVQQNTETPNILTEQDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKSKKMMEN 903 Query: 746 ----DARVSIDD------------LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMD 877 ++S++ LKNIL+ LP +Y L ++ + +V+R S N+M Sbjct: 904 LPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMT 963 Query: 878 SRTLAVEFAPLII 916 LA+ FAP +I Sbjct: 964 LYNLALVFAPGLI 976
>Q8N392:RHG18_HUMAN Rho GTPase-activating protein 18 - Homo sapiens (Human)| Length = 663 Score = 45.8 bits (107), Expect = 4e-04 Identities = 41/166 (24%), Positives = 71/166 (42%), Gaps = 26/166 (15%) Frame = +2 Query: 488 SDVFGVPVEATAQREQS---GKAVPLILVRCADHLVISGLSNEYLFKSEGD----RKVLQ 646 S +F VP+ A +++Q G +PLI + + GL E L + G + + Q Sbjct: 319 SGLFCVPLTALLEQDQRKVPGMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQ 378 Query: 647 QL-------------VSLYNEAALIKCYLASIPEPLTT------FALYDELKDARVSIDD 769 +L V ++ A+L+K ++ +P+PL + F L + + Sbjct: 379 ELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQA 438 Query: 770 LKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAP 907 L ++ LP+ N TL+ + L RV NKM +A+ AP Sbjct: 439 LNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTVMNVAMVMAP 484
>Q9BRR9:RHG09_HUMAN Rho GTPase-activating protein 9 - Homo sapiens (Human)| Length = 750 Score = 45.8 bits (107), Expect = 4e-04 Identities = 40/189 (21%), Positives = 72/189 (38%), Gaps = 41/189 (21%) Frame = +2 Query: 470 QKGVASSDVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQ 649 ++G+ VFG +E+ QRE G VP L C + GL + +++ G+ V+Q+ Sbjct: 531 ERGLLRDQVFGCQLESLCQRE--GDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQK 588 Query: 650 LVSLYNE-----------------------------------AALIKCYLASIPEPLTTF 724 L L + +K +L +P+PL Sbjct: 589 LRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPP 648 Query: 725 ALYDE------LKDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRT 886 L L ++ + ++ ++ +P N+ TL ++ L RV S N+M Sbjct: 649 LLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHN 708 Query: 887 LAVEFAPLI 913 L + F P + Sbjct: 709 LGIVFGPTL 717
>Q63744:RHG07_RAT Rho GTPase-activating protein 7 - Rattus norvegicus (Rat)| Length = 1091 Score = 45.1 bits (105), Expect = 7e-04 Identities = 45/161 (27%), Positives = 67/161 (41%), Gaps = 23/161 (14%) Frame = +2 Query: 494 VFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL------- 652 VFGVP+ QR SG+ +P + + +L L LF+ G + +Q L Sbjct: 638 VFGVPLTVNVQR--SGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESA 695 Query: 653 --------VSLYNEAALIKCYLASIPEPLTTFALYDEL--------KDARVSIDDLKNIL 784 S Y+ A ++K Y +PEPL T L + KD R+ +K + Sbjct: 696 EDYVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQA--IKAAI 753 Query: 785 KKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAP 907 LP+ N L+ + L V+ N+M LAV AP Sbjct: 754 MLLPDENREVLQTLLYFLSHVTAAVKENQMTPTNLAVCLAP 794
>Q12128:BAG7_YEAST Rho-GTPase-activating protein BAG7 - Saccharomyces cerevisiae| (Baker's yeast) Length = 409 Score = 45.1 bits (105), Expect = 7e-04 Identities = 40/181 (22%), Positives = 76/181 (41%), Gaps = 40/181 (22%) Frame = +2 Query: 494 VFGVPVEATAQREQSGK----------AVPLILVRCADHLVISGLSNEYLFKSEGDRKVL 643 VFGV +E + + Q ++P+++ + +L + L +F+ G K + Sbjct: 47 VFGVSLEESLKVAQEEVIIQKSTNEIGSIPVVIAKSGKYLKENALDTTGIFRIAGSNKRV 106 Query: 644 QQLVSLYNE-------------------AALIKCYLASIPEPLTTFALYDELKDARVS-- 760 ++L +++++ A L+K YL S+ EPL ALYD ++ + Sbjct: 107 RELQAVFSKPPDYGRKFEGWCDFNVHDIATLLKRYLNSLSEPLVPLALYDIFRNPILENP 166 Query: 761 ---------IDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLI 913 I D ++I LP N + ++ +LL +R N M + LA P + Sbjct: 167 KINEHKEQIIKDYEDIYMLLPQQNRHLILYLAALLNLFARNEKKNLMSASNLAAIVQPSL 226 Query: 914 I 916 + Sbjct: 227 L 227
>Q01968:OCRL_HUMAN Inositol polyphosphate 5-phosphatase OCRL-1 - Homo sapiens (Human)| Length = 901 Score = 44.7 bits (104), Expect = 0.001 Identities = 29/136 (21%), Positives = 61/136 (44%), Gaps = 13/136 (9%) Frame = +2 Query: 548 VPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLV-------------SLYNEAALIKC 688 VP + DHL E LF++ G ++ LQQ++ S ++ A + Sbjct: 734 VPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLI 793 Query: 689 YLASIPEPLTTFALYDELKDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALN 868 +L ++PEP+ + LY D+ + ++ +LP + ++ + L + + S N Sbjct: 794 FLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYN 853 Query: 869 KMDSRTLAVEFAPLII 916 +++ +A F L++ Sbjct: 854 SVNANMIATLFTSLLL 869
>Q9R0Z9:RHG07_MOUSE Rho GTPase-activating protein 7 - Mus musculus (Mouse)| Length = 1092 Score = 44.3 bits (103), Expect = 0.001 Identities = 45/161 (27%), Positives = 67/161 (41%), Gaps = 23/161 (14%) Frame = +2 Query: 494 VFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL------- 652 VFGVP+ QR SG+ +P + + +L L LF+ G + +Q L Sbjct: 639 VFGVPLTVNVQR--SGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESA 696 Query: 653 --------VSLYNEAALIKCYLASIPEPLTTFALYDEL--------KDARVSIDDLKNIL 784 S Y+ A ++K Y +PEPL T L + KD R+ +K + Sbjct: 697 EDNVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQA--IKAAI 754 Query: 785 KKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAP 907 LP+ N L+ + L V+ N+M LAV AP Sbjct: 755 MLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAP 795
>Q06407:RGA2_YEAST Rho-type GTPase-activating protein 2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1009 Score = 43.9 bits (102), Expect = 0.002 Identities = 44/196 (22%), Positives = 85/196 (43%), Gaps = 53/196 (27%) Frame = +2 Query: 488 SDVFGVPVEATAQREQSGKAVPLILVRCADHLVIS--GLSNEYLFKSEGDRKVLQQLV-- 655 S ++G ++A E+S VP+I+ C D + GL+ E L++ G + +++++ Sbjct: 783 SHLYGSSLQARCAYEKS--TVPIIIRCCIDRIEKDDIGLNMEGLYRKSGSQTLVEEIENE 840 Query: 656 -----SLYNE-----------------AALIKCYLASIPEPLTTFALYDELKDA------ 751 SL+++ A+++K YL +P+P+ +F++YD L D Sbjct: 841 FAQNNSLHSDTLSPKLNALLNQDIHAVASVLKRYLRKLPDPVLSFSIYDALIDLVRNNQL 900 Query: 752 ---------------------RVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALN 868 + + L I K LP + L+ + + + +V R S N Sbjct: 901 IERLPLNNDKFLDSPQKVTIYEMVLKSLLEIFKILPVEHQEVLKVLAAHIGKVRRCSERN 960 Query: 869 KMDSRTLAVEFAPLII 916 M+ L++ FAP +I Sbjct: 961 LMNLHNLSLVFAPSLI 976
>Q96QB1:RHG07_HUMAN Rho GTPase-activating protein 7 - Homo sapiens (Human)| Length = 1091 Score = 43.1 bits (100), Expect = 0.003 Identities = 44/161 (27%), Positives = 67/161 (41%), Gaps = 23/161 (14%) Frame = +2 Query: 494 VFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL------- 652 VFGVP+ QR +G+ +P + + +L L LF+ G + +Q L Sbjct: 638 VFGVPLTVNVQR--TGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGA 695 Query: 653 --------VSLYNEAALIKCYLASIPEPLTTFALYDEL--------KDARVSIDDLKNIL 784 S Y+ A ++K Y +PEPL T L + KD R+ +K + Sbjct: 696 IDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQA--IKAAI 753 Query: 785 KKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAP 907 LP+ N L+ + L V+ N+M LAV AP Sbjct: 754 MLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAP 794
>P27986:P85A_HUMAN Phosphatidylinositol 3-kinase regulatory subunit alpha - Homo| sapiens (Human) Length = 724 Score = 43.1 bits (100), Expect = 0.003 Identities = 32/160 (20%), Positives = 74/160 (46%), Gaps = 23/160 (14%) Frame = +2 Query: 551 PLILVRCADHLVISGLSNEYLFKSEGDRKVLQ--------------QLVSLYNEAALIKC 688 P +L++ + + GL L++++ + + +++ ++ A K Sbjct: 129 PPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKR 188 Query: 689 YLASIPEPLTTFALYDE---LKDARVSIDDLKNILKKL------PNVNYMTLEFVTSLLL 841 YL +P P+ A+Y E L S ++ +LKKL P+ ++TL+++ Sbjct: 189 YLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFF 248 Query: 842 RVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLRNHLR 961 ++S+ S+ N +++R L+ F+P++ S + N ++ Sbjct: 249 KLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIK 288
>Q63787:P85A_RAT Phosphatidylinositol 3-kinase regulatory subunit alpha - Rattus| norvegicus (Rat) Length = 724 Score = 42.4 bits (98), Expect = 0.005 Identities = 38/159 (23%), Positives = 79/159 (49%), Gaps = 23/159 (14%) Frame = +2 Query: 551 PLILVRCADHLVISGL--SNEYLFKSEGDRKVLQQLVS---------LYNEAAL---IKC 688 P +L++ + + GL S Y +S + L+QL+ +++E L K Sbjct: 129 PPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDPPSVDLDVFDEHVLADAFKR 188 Query: 689 YLASIPEPLTTFALYDELKDARVSI---DDLKNILKKL------PNVNYMTLEFVTSLLL 841 YLA +P P+ A+Y+E+ + +D +LKKL P+ ++TL+++ Sbjct: 189 YLADLPNPVIPVAVYNEMMSLAQEVPSSEDYIQLLKKLIRSPNIPHQYWLTLQYLLKHFF 248 Query: 842 RVSRKSALNKMDSRTLAVEFAPLIIWQQGDSGTDLRNHL 958 ++S+ S+ N +++R L+ F+ ++++ + +D HL Sbjct: 249 KLSQASSKNLLNARALSEIFSH-VLFRFPAASSDNTEHL 286
>O43052:RGA1_SCHPO Rho-type GTPase-activating protein 1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1150 Score = 42.0 bits (97), Expect = 0.006 Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 37/195 (18%) Frame = +2 Query: 470 QKGVASSDVFGVPVEATAQREQSG---------KAVPLILVRCADHLVISGLSNEYLFKS 622 +K V FGVP+E +R + K +P + + +S +F+ Sbjct: 826 KKNVKKKGTFGVPLEILVERNNAQSTVGTGVGVKHIPAFIGNTLAAMKRKDMSVVGVFRK 885 Query: 623 EGDRKVLQQLVSLYNE---------------AALIKCYLASIPEPLTTFALYD------- 736 G+ + L++L + + AAL+K +L +P+PL TF L+ Sbjct: 886 NGNIRRLKELSDMLDVSPDSIDYEQETPIQLAALLKKFLRELPDPLLTFKLFGLFITSSK 945 Query: 737 -ELKDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSAL-----NKMDSRTLAVE 898 E ++ R+ + L L LP + T+E + L V+ S + +KMD LA Sbjct: 946 LESEEERMRVLHLTICL--LPKGHRDTMEVIFGFLYWVASFSHIDDEVGSKMDIHNLATV 1003 Query: 899 FAPLIIWQQGDSGTD 943 P I++ + + D Sbjct: 1004 ITPNILYSKSNDPVD 1018
>P32019:I5P2_HUMAN Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor - Homo| sapiens (Human) Length = 993 Score = 42.0 bits (97), Expect = 0.006 Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 13/136 (9%) Frame = +2 Query: 548 VPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQL-------------VSLYNEAALIKC 688 +P L D+L + + E LF+ G R + + S ++ A + Sbjct: 829 IPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASNHSVAEALLL 888 Query: 689 YLASIPEPLTTFALYDELKDARVSIDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALN 868 +L S+PEP+ ++ Y + + K ++ LP + ++ + L + + SA N Sbjct: 889 FLESLPEPVICYSTYHNCLECSGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNSAKN 948 Query: 869 KMDSRTLAVEFAPLII 916 +D LA F L++ Sbjct: 949 HLDENILASIFGSLLL 964
>Q8K2L9:TAGAP_MOUSE T-cell activation Rho GTPase-activating protein - Mus musculus| (Mouse) Length = 714 Score = 41.2 bits (95), Expect = 0.011 Identities = 36/157 (22%), Positives = 67/157 (42%), Gaps = 26/157 (16%) Frame = +2 Query: 581 LVISGLSNEYLFKSEGDRKVLQQL--------------VSLYNEAALIKCYLASIPEPLT 718 L + G S E +F+ K ++L + ++ A + K +L IP L Sbjct: 111 LCLKGPSTEGIFRKAASEKARKELKEGLNCGVSVNLKQLPVHLLAVVFKDFLRGIPLKLL 170 Query: 719 TFALYDELKDARVS------IDDLKNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDS 880 + L+++ A I+ LK + LP N + L + +L +S+ + +NKMDS Sbjct: 171 SCDLFEDWMGALEKPTEEDRIEALKQVAGGLPRPNLLLLRHLLYVLHLISKNAEVNKMDS 230 Query: 881 RTLAVEFAPLIIWQQGDSG------TDLRNHLRFTLK 973 LA+ P ++ + D DL N ++ ++ Sbjct: 231 SNLAICIGPNMLTLKNDQSLSFQAQKDLNNKVKILVE 267
>P32873:BEM3_YEAST GTPase-activating protein BEM3 - Saccharomyces cerevisiae (Baker's| yeast) Length = 1128 Score = 40.4 bits (93), Expect = 0.018 Identities = 43/189 (22%), Positives = 82/189 (43%), Gaps = 46/189 (24%) Frame = +2 Query: 485 SSDVFGVPVEA----TAQREQSGKAVPLILVRCADHLVIS-GLSNEYLFKSEGDRKVLQQ 649 S+ +FG +E ++ + Q+ +P ++ RC ++L + G+ E +F+ G V++ Sbjct: 901 STAIFGSSLETCLRLSSHKYQNVYDLPSVVYRCLEYLYKNRGIQEEGIFRLSGSSTVIKT 960 Query: 650 L-----------VSLYNEA--------------------ALIKCYLASIP------EPLT 718 L + YNE+ L+K YL +P E Sbjct: 961 LQERFDKEYDVDLCRYNESIEAKDDEASPSLYIGVNTVSGLLKLYLRKLPHLLFGDEQFL 1020 Query: 719 TFA-LYDELKDARVSID-DLKNILKK--LPNVNYMTLEFVTSLLLRVSRKSALNKMDSRT 886 +F + DE + V I K +++ +P+ N + + LL+R++ S NKM+ R Sbjct: 1021 SFKRVVDENHNNPVQISLGFKELIESGLVPHANLSLMYALFELLVRINENSKFNKMNLRN 1080 Query: 887 LAVEFAPLI 913 L + F+P + Sbjct: 1081 LCIVFSPTL 1089
>Q6P4F7:RHGBA_HUMAN Rho GTPase-activating protein 11A precursor - Homo sapiens (Human)| Length = 1023 Score = 39.7 bits (91), Expect = 0.031 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 5/87 (5%) Frame = +2 Query: 671 AALIKCYLASIPEPLTTFALYDELKDARVSIDDLKN-----ILKKLPNVNYMTLEFVTSL 835 A L+K + +PEP+ L++ L A+ + KN + L + L + + Sbjct: 118 AGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNF 177 Query: 836 LLRVSRKSALNKMDSRTLAVEFAPLII 916 L VS +S+ NKMDS LAV FAP ++ Sbjct: 178 LRNVSLRSSENKMDSSNLAVIFAPNLL 204
>Q9UNA1:RHG26_HUMAN Rho GTPase-activating protein 26 - Homo sapiens (Human)| Length = 814 Score = 39.3 bits (90), Expect = 0.041 Identities = 34/167 (20%), Positives = 71/167 (42%), Gaps = 26/167 (15%) Frame = +2 Query: 512 EATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE------- 670 E TAQ + G + I+ +C + G++ + L++ G +Q+L+S+ + Sbjct: 380 EGTAQLDSIGFS---IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASET 436 Query: 671 -------------AALIKCYLASIPEPLT------TFALYDELKDARVSIDDLKNILKKL 793 + +K YL +P PL +F +L++ + ++ +++ +L Sbjct: 437 ETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRL 496 Query: 794 PNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQGDS 934 P N L+ + + L V+ N M L V F P ++ Q ++ Sbjct: 497 PEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEET 543
>Q80Y19:RHGBA_MOUSE Rho GTPase-activating protein 11A precursor - Mus musculus (Mouse)| Length = 987 Score = 38.5 bits (88), Expect = 0.069 Identities = 42/161 (26%), Positives = 68/161 (42%), Gaps = 20/161 (12%) Frame = +2 Query: 494 VFGVPVEATAQR--EQSGKAVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYN 667 VFGVP + + G ++ CA + + E LF+ G L+ L S + Sbjct: 46 VFGVPFNSLPHSVVPEFGHIPSFLVDACAS--LKEHIHTEGLFRKSGSVVRLKALKSKLD 103 Query: 668 E-------------AALIKCYLASIPEPLTTFALYDELKDARVSIDDLKNILKKL----- 793 + A L+K + +PEP+ L++ L A+ + +N L Sbjct: 104 QGEACLSSALPCDVAGLLKQFFRELPEPVLPADLHEALFKAQQLGAEERNKATLLLSCLM 163 Query: 794 PNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLII 916 N L + + L VS +++ NKMDS LAV FAP ++ Sbjct: 164 ANPTVDILRYFFNFLKSVSLRASENKMDSSNLAVIFAPNLL 204
>P35688:LRG1_YEAST Rho-GTPase-activating protein LRG1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1017 Score = 38.5 bits (88), Expect = 0.069 Identities = 36/151 (23%), Positives = 68/151 (45%), Gaps = 27/151 (17%) Frame = +2 Query: 548 VPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE----------------AAL 679 +P+I+ L +S E +F+ G+ + L++L + + +AL Sbjct: 754 IPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTEAPDFSKENAIQLSAL 813 Query: 680 IKCYLASIPEPLTTFALYD-ELKDARVSIDDLKN-----ILKKLPNVNYMTLEFVTSLLL 841 +K ++ +P+P+ + LY+ +K A++ ++D K I LP N LE + S L Sbjct: 814 LKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQRVILLIYSLLPTYNRNLLEALLSFLH 873 Query: 842 RVSRKSAL-----NKMDSRTLAVEFAPLIIW 919 S S + +KMD L+ P I++ Sbjct: 874 WTSSFSYIENEMGSKMDIHNLSTVITPNILY 904
>P17121:SAC7_YEAST GTPase-activating protein SAC7 - Saccharomyces cerevisiae (Baker's| yeast) Length = 654 Score = 35.8 bits (81), Expect = 0.45 Identities = 18/86 (20%), Positives = 43/86 (50%), Gaps = 19/86 (22%) Frame = +2 Query: 548 VPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNE------------------- 670 +P+++ +C +L +GL +F+ G+ K ++ L +++ Sbjct: 150 IPIVVAKCGAYLKANGLETSGIFRIAGNGKRVKALQYIFSSPPDYGTKFNDWETYTVHDV 209 Query: 671 AALIKCYLASIPEPLTTFALYDELKD 748 A+L++ YL ++ EPL +LY++ ++ Sbjct: 210 ASLLRRYLNNLAEPLIPLSLYEQFRN 235
>Q8BN58:RHG28_MOUSE Rho GTPase-activating protein 28 - Mus musculus (Mouse)| Length = 729 Score = 35.0 bits (79), Expect = 0.77 Identities = 33/171 (19%), Positives = 71/171 (41%), Gaps = 27/171 (15%) Frame = +2 Query: 494 VFGVPVEATAQREQS---GKAVPLILVRCADHLVISGLSNEYLFKSEGD----RKVLQQL 652 +FGVP+ ++ VPL+L + + SGL +E +F+ G ++ ++L Sbjct: 381 IFGVPLTVLLDNDRKKDPAVKVPLVLQKFFQKVEESGLESEGIFRLSGCTAKVKQYREEL 440 Query: 653 VSLYNE-------------AALIKCYLASIPEPL-------TTFALYDELKDARVSIDDL 772 + +N A ++K + +P L +L + D +V L Sbjct: 441 DARFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPDIKVQFQAL 500 Query: 773 KNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQ 925 ++ LP+ N T + + + +V + N+M+ ++ AP + + + Sbjct: 501 HLMVMALPDANRDTAQALMAFFNKVIANESKNRMNLWNISTVMAPNLFFSR 551
>Q74ZH7:BEM3_ASHGO GTPase-activating protein BEM3 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 1013 Score = 33.9 bits (76), Expect = 1.7 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 10/97 (10%) Frame = +2 Query: 653 VSLYNEAALIKCYLASIPEPLTTFALYDELKD-ARVSIDDLKNI---LKKLPNVNYMTLE 820 V + + L+K YL +P + A Y + K + DD K I + L N + E Sbjct: 880 VDVNTVSGLLKLYLRKLPHMIFGDAAYMDFKRIVERNGDDSKLIALEFRALVNSGRIAKE 939 Query: 821 FVT------SLLLRVSRKSALNKMDSRTLAVEFAPLI 913 +V LL++++ S NKM+ R L + F+P + Sbjct: 940 YVALMYALFELLVKITENSKYNKMNLRNLCIVFSPTL 976
>Q9ZCI1:TRME_RICPR Probable tRNA modification GTPase trmE - Rickettsia prowazekii| Length = 445 Score = 33.5 bits (75), Expect = 2.2 Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 4/108 (3%) Frame = +2 Query: 491 DVFGVPVEATAQREQSGKAVPLILVRCADHLVISGLSNEYLFKSEG-DRKVLQQLVSLYN 667 D G+ E+T EQ G + + A+ ++ +F +E D + + L + Sbjct: 269 DTAGIRTESTDIIEQEGIKRAINSAKTANIKIV-------MFDAEKLDSSINNDITGLID 321 Query: 668 EAALIKCYLASIPEPLTTFALYDELKDARVSIDD---LKNILKKLPNV 802 E ++ + EP TFA+ + K RVS+ + L NILK + N+ Sbjct: 322 ENTIVIINKIDLIEPNKTFAIENRYKCLRVSVKNNIALSNILKNIENI 369
>P22194:SDS22_SCHPO Protein phosphatase 1 regulatory subunit SDS22 -| Schizosaccharomyces pombe (Fission yeast) Length = 332 Score = 33.5 bits (75), Expect = 2.2 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 13/98 (13%) Frame = +2 Query: 635 KVLQQLVSLYNEAALIKCYLASIPEPLTTFALYDELKDARVSIDDLKNI---------LK 787 K LQ L N+ I+ S+PE LT LYD L ++D++KN+ +K Sbjct: 62 KNLQSLCLRQNQIKKIE----SVPETLTELDLYDNLIVRIENLDNVKNLTYLDLSFNNIK 117 Query: 788 KLPNVNYM----TLEFVTSLLLRVSRKSALNKMDSRTL 889 + N+N++ L FV + + R+ L+++ + L Sbjct: 118 TIRNINHLKGLENLFFVQNRIRRIENLEGLDRLTNLEL 155
>Q9P2N2:RHG28_HUMAN Rho GTPase-activating protein 28 - Homo sapiens (Human)| Length = 729 Score = 33.5 bits (75), Expect = 2.2 Identities = 32/171 (18%), Positives = 71/171 (41%), Gaps = 27/171 (15%) Frame = +2 Query: 494 VFGVPVEATA---QREQSGKAVPLILVRCADHLVISGLSNEYLFKSEG----DRKVLQQL 652 +FGVP+ +++ G VPL+L + + + SGL +E +F+ G ++ ++L Sbjct: 377 IFGVPLTVLLDGDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREEL 436 Query: 653 VSLYN-------------EAALIKCYLASIPEPL-------TTFALYDELKDARVSIDDL 772 + +N A ++K + +P L +L + +V L Sbjct: 437 DAKFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQAL 496 Query: 773 KNILKKLPNVNYMTLEFVTSLLLRVSRKSALNKMDSRTLAVEFAPLIIWQQ 925 ++ LP+ N + + + +V + N+M ++ AP + + + Sbjct: 497 HLMVMALPDANRDAAQALMTFFNKVIANESKNRMSLWNISTVMAPNLFFSR 547
>Q6G1K9:GIDA_BARHE tRNA uridine 5-carboxymethylaminomethyl modification enzyme gidA -| Bartonella henselae (Rochalimaea henselae) Length = 622 Score = 32.3 bits (72), Expect = 5.0 Identities = 17/58 (29%), Positives = 28/58 (48%) Frame = +2 Query: 152 FFSSSSFKLKQAGQSAGDNIADVAGKVGTVVKSRWAIFQDARQRPPLPGDTVQERFIS 325 F S + F+L +A + +A ++G V K RW +Q +QR QE F++ Sbjct: 425 FTSRAEFRLSLRSDNADARLTPLAQQLGIVSKLRWECYQKKQQRLDQARSLCQELFLT 482
>Q9SSQ2:FB55_ARATH F-box protein At1g52490 - Arabidopsis thaliana (Mouse-ear cress)| Length = 423 Score = 32.3 bits (72), Expect = 5.0 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 4/91 (4%) Frame = +2 Query: 728 LYDELKDARVSIDDLKNILKKLPNVNYMTLEFVTS--LLLRVSRKSALNKMDSRTL--AV 895 L +LKD + +D + ILKKLP + M V+ + R+ + + +R+L Sbjct: 46 LLSKLKDVHLPLDLIVEILKKLPTKSLMRFRCVSKPWSFIISKRRDFVESIMARSLRQPP 105 Query: 896 EFAPLIIWQQGDSGTDLRNHLRFTLKPPPKI 988 P+ I+ Q D GT F+ PK+ Sbjct: 106 HKLPVFIFHQCDPGTFFTVSSTFSQSTKPKV 136
>Q80YA7:DPP8_MOUSE Dipeptidyl peptidase 8 - Mus musculus (Mouse)| Length = 892 Score = 32.0 bits (71), Expect = 6.5 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 1/110 (0%) Frame = +2 Query: 500 GVPVEATAQREQSGK-AVPLILVRCADHLVISGLSNEYLFKSEGDRKVLQQLVSLYNEAA 676 GV A A GK A ++L R HL I +S E E D Q+L+ Sbjct: 368 GVEYIARAGWTPEGKHAWSILLDRSQTHLQIVLISPELFIPVEDDAMDRQRLIE------ 421 Query: 677 LIKCYLASIPEPLTTFALYDELKDARVSIDDLKNILKKLPNVNYMTLEFV 826 S+P+ +T +Y+E D ++I D+ ++ P + +EF+ Sbjct: 422 -------SVPDSVTPLIIYEETTDIWINIHDIFHV---FPQTHEDEIEFI 461 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 248,984,943 Number of extensions: 5510775 Number of successful extensions: 14086 Number of sequences better than 10.0: 106 Number of HSP's gapped: 14031 Number of HSP's successfully gapped: 107 Length of query: 473 Length of database: 100,686,439 Length adjustment: 117 Effective length of query: 356 Effective length of database: 68,593,924 Effective search space: 24419436944 Effective search space used: 24419436944 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
