Clone Information

BLAST Search Result

Clone Name	FLbaf31e08
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	P12694:ODBA_HUMAN 2-oxoisovalerate dehydrogenase subunit alpha, ...	389	e-107
2	Q8HXY4:ODBA_MACFA 2-oxoisovalerate dehydrogenase subunit alpha, ...	387	e-106
3	P11960:ODBA_RAT 2-oxoisovalerate dehydrogenase subunit alpha, mi...	384	e-106
4	P50136:ODBA_MOUSE 2-oxoisovalerate dehydrogenase subunit alpha, ...	384	e-106
5	P11178:ODBA_BOVIN 2-oxoisovalerate dehydrogenase subunit alpha, ...	384	e-106
6	Q72GU1:ODBA_THET2 2-oxoisovalerate dehydrogenase subunit alpha -...	221	8e-57
7	Q5SLR4:ODBA_THET8 2-oxoisovalerate dehydrogenase subunit alpha -...	218	7e-56
8	Q9I1M2:ODBA_PSEAE 2-oxoisovalerate dehydrogenase subunit alpha -...	217	1e-55
9	P21873:ODPA_BACST Pyruvate dehydrogenase E1 component, alpha sub...	216	2e-55
10	P60090:ODPA_STAAW Pyruvate dehydrogenase E1 component subunit al...	213	3e-54
11	Q6GAC1:ODPA_STAAS Pyruvate dehydrogenase E1 component subunit al...	213	3e-54
12	Q820A6:ODPA_STAAN Pyruvate dehydrogenase E1 component subunit al...	213	3e-54
13	P60089:ODPA_STAAM Pyruvate dehydrogenase E1 component subunit al...	213	3e-54
14	Q5HGZ1:ODPA_STAAC Pyruvate dehydrogenase E1 component subunit al...	213	3e-54
15	P21881:ODPA_BACSU Pyruvate dehydrogenase E1 component subunit al...	211	6e-54
16	Q8CPN3:ODPA_STAES Pyruvate dehydrogenase E1 component subunit al...	211	8e-54
17	Q5HQ76:ODPA_STAEQ Pyruvate dehydrogenase E1 component subunit al...	211	8e-54
18	Q6GHZ2:ODPA_STAAR Pyruvate dehydrogenase E1 component subunit al...	211	8e-54
19	Q4MTG0:ODPA_BACCE Pyruvate dehydrogenase E1 component, alpha sub...	207	1e-52
20	P09060:ODBA_PSEPU 2-oxoisovalerate dehydrogenase subunit alpha -...	203	2e-51
21	P37940:ODBA_BACSU 2-oxoisovalerate dehydrogenase subunit alpha -...	186	3e-46
22	P35485:ODPA_ACHLA Pyruvate dehydrogenase E1 component subunit al...	169	3e-41
23	P26268:ODPT_ASCSU Pyruvate dehydrogenase E1 component alpha subu...	143	2e-33
24	P75390:ODPA_MYCPN Pyruvate dehydrogenase E1 component subunit al...	143	3e-33
25	P47516:ODPA_MYCGE Pyruvate dehydrogenase E1 component subunit al...	142	6e-33
26	P52901:ODPA1_ARATH Pyruvate dehydrogenase E1 component subunit a...	140	2e-32
27	Q8H1Y0:ODPA2_ARATH Pyruvate dehydrogenase E1 component subunit a...	140	2e-32
28	P26267:ODPA_ASCSU Pyruvate dehydrogenase E1 component alpha subu...	139	3e-32
29	P16387:ODPA_YEAST Pyruvate dehydrogenase E1 component subunit al...	135	7e-31
30	P52903:ODPA_SOLTU Pyruvate dehydrogenase E1 component subunit al...	133	3e-30
31	Q1XDM0:ODPA_PORYE Pyruvate dehydrogenase E1 component subunit al...	133	3e-30
32	Q10489:ODPA_SCHPO Pyruvate dehydrogenase E1 component alpha subu...	132	6e-30
33	P52902:ODPA_PEA Pyruvate dehydrogenase E1 component subunit alph...	131	1e-29
34	O13366:ODPA_KLULA Pyruvate dehydrogenase E1 component alpha subu...	131	1e-29
35	Q9R9N5:ODPA_RHIME Pyruvate dehydrogenase E1 component subunit al...	130	2e-29
36	P51267:ODPA_PORPU Pyruvate dehydrogenase E1 component subunit al...	125	4e-28
37	P52899:ODPA_CAEEL Probable pyruvate dehydrogenase E1 component a...	125	6e-28
38	P52900:ODPA_SMIMA Pyruvate dehydrogenase E1 component alpha subu...	123	3e-27
39	Q5R490:ODPA_PONPY Pyruvate dehydrogenase E1 component alpha subu...	122	4e-27
40	P08559:ODPA_HUMAN Pyruvate dehydrogenase E1 component alpha subu...	122	5e-27
41	P29804:ODPA_PIG Pyruvate dehydrogenase E1 component alpha subuni...	122	6e-27
42	Q8HXW9:ODPA_MACFA Pyruvate dehydrogenase E1 component alpha subu...	121	8e-27
43	O66112:ODPA_ZYMMO Pyruvate dehydrogenase E1 component subunit al...	120	2e-26
44	Q06437:ODPAT_RAT Pyruvate dehydrogenase E1 component alpha subun...	120	2e-26
45	Q1RJX4:ODPA_RICBR Pyruvate dehydrogenase E1 component subunit al...	119	4e-26
46	P35486:ODPA_MOUSE Pyruvate dehydrogenase E1 component alpha subu...	117	1e-25
47	P29803:ODPAT_HUMAN Pyruvate dehydrogenase E1 component alpha sub...	117	2e-25
48	P26284:ODPA_RAT Pyruvate dehydrogenase E1 component alpha subuni...	117	2e-25
49	Q4UKQ6:ODPA_RICFE Pyruvate dehydrogenase E1 component subunit al...	116	3e-25
50	P35487:ODPAT_MOUSE Pyruvate dehydrogenase E1 component alpha sub...	115	8e-25
51	Q92IS3:ODPA_RICCN Pyruvate dehydrogenase E1 component subunit al...	112	7e-24
52	Q9ZDR4:ODPA_RICPR Pyruvate dehydrogenase E1 component subunit al...	111	9e-24
53	Q68XA9:ODPA_RICTY Pyruvate dehydrogenase E1 component subunit al...	107	1e-22
54	P27745:ACOA_RALEH Acetoin:2,6-dichlorophenolindophenol oxidoredu...	105	5e-22
55	Q9ZM94:DXS_HELPJ 1-deoxy-D-xylulose-5-phosphate synthase - Helic...	42	0.006
56	Q92RJ1:DXS_RHIME 1-deoxy-D-xylulose-5-phosphate synthase - Rhizo...	42	0.011
57	Q21UG7:DXS_RHOFD 1-deoxy-D-xylulose-5-phosphate synthase - Rhodo...	41	0.014
58	Q1MKN4:DXS_RHIL3 1-deoxy-D-xylulose-5-phosphate synthase - Rhizo...	40	0.024
59	O25121:DXS_HELPY 1-deoxy-D-xylulose-5-phosphate synthase - Helic...	40	0.024
60	Q1CUF6:DXS_HELPH 1-deoxy-D-xylulose-5-phosphate synthase - Helic...	40	0.024
61	Q47BJ0:DXS_DECAR 1-deoxy-D-xylulose-5-phosphate synthase - Dechl...	40	0.042
62	Q7VIJ7:DXS_HELHP 1-deoxy-D-xylulose-5-phosphate synthase - Helic...	39	0.054
63	Q82VD3:DXS_NITEU 1-deoxy-D-xylulose-5-phosphate synthase - Nitro...	39	0.071
64	Q8G292:DXS_BRUSU 1-deoxy-D-xylulose-5-phosphate synthase - Bruce...	39	0.071
65	Q8YFM2:DXS_BRUME 1-deoxy-D-xylulose-5-phosphate synthase - Bruce...	39	0.071
66	Q57ET1:DXS_BRUAB 1-deoxy-D-xylulose-5-phosphate synthase - Bruce...	39	0.071
67	Q2YMF0:DXS_BRUA2 1-deoxy-D-xylulose-5-phosphate synthase - Bruce...	39	0.071
68	Q2KBR2:DXS_RHIEC 1-deoxy-D-xylulose-5-phosphate synthase - Rhizo...	39	0.093
69	Q11KE0:DXS_MESSB 1-deoxy-D-xylulose-5-phosphate synthase - Mesor...	39	0.093
70	Q6A6X1:GUAA_PROAC GMP synthase [glutamine-hydrolyzing] - Propion...	38	0.12
71	Q3AD70:GUAA_CARHZ GMP synthase [glutamine-hydrolyzing] - Carboxy...	38	0.16
72	Q5HWF0:DXS_CAMJR 1-deoxy-D-xylulose-5-phosphate synthase - Campy...	38	0.16
73	Q9PIH8:DXS_CAMJE 1-deoxy-D-xylulose-5-phosphate synthase - Campy...	38	0.16
74	Q4FN07:DXS_PELUB 1-deoxy-D-xylulose-5-phosphate synthase - Pelag...	37	0.21
75	O22567:DXS_ORYSJ Probable 1-deoxy-D-xylulose-5-phosphate synthas...	37	0.21
76	Q58094:TKTN_METJA Putative transketolase N-terminal section - Me...	37	0.27
77	Q60AN1:DXS_METCA 1-deoxy-D-xylulose-5-phosphate synthase - Methy...	37	0.27
78	Q47LQ0:GUAA_THEFY GMP synthase [glutamine-hydrolyzing] - Thermob...	37	0.35
79	Q2YCH7:DXS_NITMU 1-deoxy-D-xylulose-5-phosphate synthase - Nitro...	37	0.35
80	Q2NKZ4:TKTL2_BOVIN Transketolase-like protein 2 - Bos taurus (Bo...	36	0.46
81	Q8XX95:DXS_RALSO 1-deoxy-D-xylulose-5-phosphate synthase - Ralst...	36	0.46
82	Q9KGU7:DXS_PSEAE 1-deoxy-D-xylulose-5-phosphate synthase - Pseud...	36	0.46
83	Q3JDG3:GUAA_NITOC GMP synthase [glutamine-hydrolyzing] - Nitroso...	36	0.60
84	Q7M7Z0:DXS_WOLSU 1-deoxy-D-xylulose-5-phosphate synthase - Wolin...	36	0.60
85	Q8UHD7:DXS_AGRT5 1-deoxy-D-xylulose-5-phosphate synthase - Agrob...	36	0.60
86	P22976:TKT_STRPN Probable transketolase - Streptococcus pneumoniae	35	0.78
87	Q985Y3:DXS_RHILO 1-deoxy-D-xylulose-5-phosphate synthase - Rhizo...	35	0.78
88	Q4K5A5:DXS_PSEF5 1-deoxy-D-xylulose-5-phosphate synthase - Pseud...	35	0.78
89	Q2SA08:DXS_HAHCH 1-deoxy-D-xylulose-5-phosphate synthase - Hahel...	35	0.78
90	Q38854:DXS_ARATH Probable 1-deoxy-D-xylulose-5-phosphate synthas...	35	0.78
91	Q5R1W6:TKT_PANTR Transketolase - Pan troglodytes (Chimpanzee)	35	1.0
92	P29401:TKT_HUMAN Transketolase - Homo sapiens (Human)	35	1.0
93	Q7UFS3:GUAA_RHOBA GMP synthase [glutamine-hydrolyzing] - Rhodopi...	35	1.0
94	Q8G5P4:GUAA_BIFLO GMP synthase [glutamine-hydrolyzing] - Bifidob...	35	1.0
95	Q30TC5:DXS_THIDN 1-deoxy-D-xylulose-5-phosphate synthase - Thiom...	35	1.0
96	Q21F93:DXS_SACD2 1-deoxy-D-xylulose-5-phosphate synthase - Sacch...	35	1.0
97	Q6NB76:DXS_RHOPA 1-deoxy-D-xylulose-5-phosphate synthase - Rhodo...	35	1.0
98	Q16DV7:DXS1_ROSDO 1-deoxy-D-xylulose-5-phosphate synthase 1 - Ro...	35	1.0
99	P50137:TKT_RAT Transketolase - Rattus norvegicus (Rat)	35	1.3
100	Q6B855:TKT_BOVIN Transketolase - Bos taurus (Bovine)	35	1.3
101	Q3K660:DXS_PSEPF 1-deoxy-D-xylulose-5-phosphate synthase - Pseud...	35	1.3
102	P55574:Y4MO_RHISN Putative uncharacterized transketolase family ...	34	1.7
103	Q5R4C1:TKT_PONPY Transketolase - Pongo pygmaeus (Orangutan)	34	1.7
104	P40142:TKT_MOUSE Transketolase - Mus musculus (Mouse)	34	1.7
105	Q60HC7:TKT_MACFA Transketolase - Macaca fascicularis (Crab eatin...	34	1.7
106	Q9D4D4:TKTL2_MOUSE Transketolase-like protein 2 - Mus musculus (...	34	2.3
107	Q8NRC3:ODO1_CORGL 2-oxoglutarate dehydrogenase E1 component - Co...	34	2.3
108	Q1GQK9:DXS_SPHAL 1-deoxy-D-xylulose-5-phosphate synthase - Sphin...	34	2.3
109	Q1LK34:DXS_RALME 1-deoxy-D-xylulose-5-phosphate synthase - Ralst...	34	2.3
110	Q1D3G4:DXS_MYXXD 1-deoxy-D-xylulose-5-phosphate synthase - Myxoc...	34	2.3
111	Q2T7N5:DXS_BURTA 1-deoxy-D-xylulose-5-phosphate synthase - Burkh...	34	2.3
112	Q63JF4:DXS_BURPS 1-deoxy-D-xylulose-5-phosphate synthase - Burkh...	34	2.3
113	Q3JKA3:DXS_BURP1 1-deoxy-D-xylulose-5-phosphate synthase - Burkh...	34	2.3
114	Q62DU1:DXS_BURMA 1-deoxy-D-xylulose-5-phosphate synthase - Burkh...	34	2.3
115	Q6G0D4:DXS_BARQU 1-deoxy-D-xylulose-5-phosphate synthase - Barto...	34	2.3
116	Q6G4D1:DXS_BARHE 1-deoxy-D-xylulose-5-phosphate synthase - Barto...	34	2.3
117	Q5NM38:DXS2_ZYMMO 1-deoxy-D-xylulose-5-phosphate synthase 2 - Zy...	34	2.3
118	Q5NN52:DXS1_ZYMMO 1-deoxy-D-xylulose-5-phosphate synthase 1 - Zy...	34	2.3
119	Q8PXG9:RBL_METMA Ribulose bisphosphate carboxylase - Methanosarc...	33	3.0
120	P0A5A1:GUAA_MYCTU GMP synthase [glutamine-hydrolyzing] - Mycobac...	33	3.0
121	P0A5A2:GUAA_MYCBO GMP synthase [glutamine-hydrolyzing] - Mycobac...	33	3.0
122	Q2GC13:DXS_NOVAD 1-deoxy-D-xylulose-5-phosphate synthase - Novos...	33	3.0
123	Q3ZXC2:DXS_DEHSC 1-deoxy-D-xylulose-5-phosphate synthase - Dehal...	33	3.0
124	Q3Z8G9:DXS_DEHE1 1-deoxy-D-xylulose-5-phosphate synthase - Dehal...	33	3.0
125	Q13RX1:DXS_BURXL 1-deoxy-D-xylulose-5-phosphate synthase - Burkh...	33	3.0
126	Q9H0I9:TKTL2_HUMAN Transketolase-like protein 2 - Homo sapiens (...	33	3.9
127	Q88QG7:DXS_PSEPK 1-deoxy-D-xylulose-5-phosphate synthase - Pseud...	33	3.9
128	Q8CJ78:ZN628_MOUSE Zinc finger protein 628 - Mus musculus (Mouse)	33	5.1
129	Q8CGF7:TCRG1_MOUSE Transcription elongation regulator 1 - Mus mu...	33	5.1
130	O14776:TCRG1_HUMAN Transcription elongation regulator 1 - Homo s...	33	5.1
131	Q02137:ILVB_LACLA Acetolactate synthase large subunit - Lactococ...	33	5.1
132	Q24V05:DXS_DESHY 1-deoxy-D-xylulose-5-phosphate synthase - Desul...	33	5.1
133	Q2RR29:DXS2_RHORT 1-deoxy-D-xylulose-5-phosphate synthase 2 - Rh...	33	5.1
134	Q2RYD6:DXS1_RHORT 1-deoxy-D-xylulose-5-phosphate synthase 1 - Rh...	33	5.1
135	P63984:DPO3_STRA5 DNA polymerase III polC-type - Streptococcus a...	33	5.1
136	P63983:DPO3_STRA3 DNA polymerase III polC-type - Streptococcus a...	33	5.1
137	Q87RU0:DXS_VIBPA 1-deoxy-D-xylulose-5-phosphate synthase - Vibri...	32	6.6
138	Q474C2:DXS_RALEJ 1-deoxy-D-xylulose-5-phosphate synthase - Ralst...	32	6.6
139	Q4ZYU8:DXS_PSEU2 1-deoxy-D-xylulose-5-phosphate synthase - Pseud...	32	6.6
140	Q2W367:DXS_MAGMM 1-deoxy-D-xylulose-5-phosphate synthase - Magne...	32	6.6
141	O78328:DXS_CAPAN Probable 1-deoxy-D-xylulose-5-phosphate synthas...	32	6.6
142	Q1BLY7:DXS_BURCA 1-deoxy-D-xylulose-5-phosphate synthase - Burkh...	32	6.6
143	Q6D1S9:RECX_ERWCT Regulatory protein recX - Erwinia carotovora s...	32	8.7
144	Q6L126:RADA_PICTO DNA repair and recombination protein radA - Pi...	32	8.7
145	P49057:GUAA_SYNY3 GMP synthase [glutamine-hydrolyzing] - Synecho...	32	8.7
146	Q6AD51:GUAA_LEIXX GMP synthase [glutamine-hydrolyzing] - Leifson...	32	8.7
147	Q9KF78:GUAA_BACHD Putative GMP synthase [glutamine-hydrolyzing] ...	32	8.7
148	Q889Q1:DXS_PSESM 1-deoxy-D-xylulose-5-phosphate synthase - Pseud...	32	8.7
149	Q48NX0:DXS_PSE14 1-deoxy-D-xylulose-5-phosphate synthase - Pseud...	32	8.7
150	Q1QQ40:DXS_NITHX 1-deoxy-D-xylulose-5-phosphate synthase - Nitro...	32	8.7
151	Q487D3:DXS_COLP3 1-deoxy-D-xylulose-5-phosphate synthase - Colwe...	32	8.7
152	Q393P4:DXS_BURS3 1-deoxy-D-xylulose-5-phosphate synthase - Burkh...	32	8.7

>P12694:ODBA_HUMAN 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor|
            - Homo sapiens (Human)
          Length = 445
 Score =  389 bits (998), Expect = e-107
 Identities = 189/388 (48%), Positives = 247/388 (63%)
 Frame = +1

Query: 463  FPGGKLSFVGEMNFLPESQTERINCYRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQ 642
            FPG    F+ ++ F+  +    I  YRV+D  G  I  S    + K+  LK+Y +M  L 
Sbjct: 54   FPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLN 113

Query: 643  IMDTIFYEAQRQGRISFYLTSNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQE 822
             MD I YE+QRQGRISFY+T+ GEE             D+V  QYRE GVL++R + L+ 
Sbjct: 114  TMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLEL 173

Query: 823  FANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAI 1002
            F  Q +GN  D GKGRQMP+HYG    ++ T+SSP+ATQ+PQAVGAAY+ K        I
Sbjct: 174  FMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVI 233

Query: 1003 TYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGI 1182
             YFG+G  SEGD HA  NFAA  E P+IFFCRNNG+AISTPT+EQ+R DG+  RG  YGI
Sbjct: 234  CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 293

Query: 1183 RSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEH 1362
             SIR+DGND  AVY+A   AR  A+ E +P LIEAMTYR+GHHSTSDDS+ YR  DE+ +
Sbjct: 294  MSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 353

Query: 1363 WRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVY 1542
            W     P+SR R ++   GWW   QE   R   R+++++A + AER PK     LF+DVY
Sbjct: 354  WDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVY 413

Query: 1543 DQIPSNLRQQERSLLDTIKRHPAEYPAD 1626
             ++P+ LR+Q+ SL   ++ +   YP D
Sbjct: 414  QEMPAQLRKQQESLARHLQTYGEHYPLD 441

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>Q8HXY4:ODBA_MACFA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor|
            - Macaca fascicularis (Crab eating macaque) (Cynomolgus
            monkey)
          Length = 445

 Score =  387 bits (993), Expect = e-106
 Identities = 188/388 (48%), Positives = 247/388 (63%)
 Frame = +1

Query: 463  FPGGKLSFVGEMNFLPESQTERINCYRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQ 642
            FPG    F+ ++ F+  +    I  YRV+D  G  I  S    + K+  LK+Y +M  L 
Sbjct: 54   FPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLN 113

Query: 643  IMDTIFYEAQRQGRISFYLTSNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQE 822
             MD I YE+QRQGRISFY+T+ GEE             D+V  QYRE GVL++R + L+ 
Sbjct: 114  TMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLEL 173

Query: 823  FANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAI 1002
            F  Q +GN  D GKGRQMP+HYG    ++ T+SSP+ATQ+PQAVGAAY+ K        I
Sbjct: 174  FMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVI 233

Query: 1003 TYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGI 1182
             YFG+G  SEGD HA  NFAA  E P+IFFCRNNG+AISTPT+EQ+R DG+  RG  YGI
Sbjct: 234  CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 293

Query: 1183 RSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEH 1362
             SIR+DGND  AVY+A   AR  A+ E +P LIEAMTYR+GHHSTSDDS+ YR  DE+ +
Sbjct: 294  MSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 353

Query: 1363 WRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVY 1542
            W     P+SR R ++   GWW   QE   R   R+++++A + AER PK     LF+DVY
Sbjct: 354  WDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRKKVMKAFEQAERKPKPNPNLLFSDVY 413

Query: 1543 DQIPSNLRQQERSLLDTIKRHPAEYPAD 1626
             ++P+ LR+Q+ SL   ++ +   YP +
Sbjct: 414  QEMPAQLRKQQESLARHLQTYGEHYPLE 441

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>P11960:ODBA_RAT 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor|
            - Rattus norvegicus (Rat)
          Length = 441

 Score =  384 bits (987), Expect = e-106
 Identities = 188/388 (48%), Positives = 248/388 (63%)
 Frame = +1

Query: 463  FPGGKLSFVGEMNFLPESQTERINCYRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQ 642
            FPG    FV ++ F+  +    I  YRV+D  G  I  S    + ++  LK+Y +M  L 
Sbjct: 50   FPGASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVLKLYRSMTLLN 109

Query: 643  IMDTIFYEAQRQGRISFYLTSNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQE 822
             MD I YE+QRQGRISFY+T+ GEE             D+V  QYRE GVL++R + L+ 
Sbjct: 110  TMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALERTDLVFGQYREAGVLMYRDYPLEL 169

Query: 823  FANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAI 1002
            F  Q +GN  D GKGRQMP+HYG    ++ T+SSP+ATQ+PQAVGAAY+ K        I
Sbjct: 170  FMAQCYGNVSDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANQIVI 229

Query: 1003 TYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGI 1182
             YFG+G  SEGD HA  NFAA  E P+IFFCRNNG+AISTPT+EQ+R DG+  RG  YGI
Sbjct: 230  CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 289

Query: 1183 RSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEH 1362
             SIR+DGND  AVY+A   AR  A+ E +P LIEAMTYR+GHHSTSDDS+ YR  DE+ +
Sbjct: 290  MSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 349

Query: 1363 WRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVY 1542
            W     P+SR R+++   GWW   QE   R   R+++++A + AER  K   + LF+DVY
Sbjct: 350  WDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLLFSDVY 409

Query: 1543 DQIPSNLRQQERSLLDTIKRHPAEYPAD 1626
             ++P+ LR+Q+ SL   ++ +   YP D
Sbjct: 410  QEMPAQLRRQQESLARHLQTYGEHYPLD 437

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>P50136:ODBA_MOUSE 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor|
            - Mus musculus (Mouse)
          Length = 442

 Score =  384 bits (987), Expect = e-106
 Identities = 187/388 (48%), Positives = 249/388 (64%)
 Frame = +1

Query: 463  FPGGKLSFVGEMNFLPESQTERINCYRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQ 642
            FPG    FV ++ F+  +    I  YRV+D  G  I  S    + ++  LK Y +M  L 
Sbjct: 51   FPGASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVLKFYRSMTLLN 110

Query: 643  IMDTIFYEAQRQGRISFYLTSNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQE 822
             MD I YE+QR+GRISFY+T+ GEE             D+V  QYRE GVL++R + L+ 
Sbjct: 111  TMDRILYESQREGRISFYMTNYGEEGTHVGSAAALERTDLVFGQYREAGVLMYRDYPLEL 170

Query: 823  FANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAI 1002
            F +Q +GN  D GKGRQMP+HYG    ++ T+SSP+ATQ+PQAVGAAY+ K        I
Sbjct: 171  FMSQCYGNVNDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRIVI 230

Query: 1003 TYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGI 1182
             YFG+G  SEGD HA  NFAA  E P+IFFCRNNG+AISTPT+EQ+R DG+  RG  YGI
Sbjct: 231  CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 290

Query: 1183 RSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEH 1362
            +SIR+DGND  AVY+A   AR  A+ E +P LIEAMTYR+GHHSTSDDS+ YR  DE+ +
Sbjct: 291  KSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 350

Query: 1363 WRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVY 1542
            W     P+SR R+++   GWW   QE   R   R+++++A + AER  K   + LF+DVY
Sbjct: 351  WDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLLFSDVY 410

Query: 1543 DQIPSNLRQQERSLLDTIKRHPAEYPAD 1626
             ++P+ LR+Q+ SL   ++ +   YP D
Sbjct: 411  QEMPAQLRRQQESLARHLQTYGEHYPLD 438

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>P11178:ODBA_BOVIN 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor|
            - Bos taurus (Bovine)
          Length = 455

 Score =  384 bits (987), Expect = e-106
 Identities = 187/388 (48%), Positives = 246/388 (63%)
 Frame = +1

Query: 463  FPGGKLSFVGEMNFLPESQTERINCYRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQ 642
            FPG    F+ ++ F+  +    I  YRV+D  G  I  S    + ++  LK Y +M  L 
Sbjct: 64   FPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEKVLKFYKSMTLLN 123

Query: 643  IMDTIFYEAQRQGRISFYLTSNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQE 822
             MD I YE+QRQGRISFY+T+ GEE             D+V  QYRE GVL++R + L+ 
Sbjct: 124  TMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDDTDLVFGQYREAGVLMYRDYPLEL 183

Query: 823  FANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAI 1002
            F  Q +GN  D GKGRQMP+HYG    ++ T+SSP+ATQ+PQAVGAAY+ K        I
Sbjct: 184  FMAQCYGNVSDLGKGRQMPVHYGCRERHFVTISSPLATQIPQAVGAAYAAKRANANRVVI 243

Query: 1003 TYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGI 1182
             YFG+G  SEGD HA  NFAA  E P+IFFCRNNG+AISTPT+EQ+R DG+  RG  YGI
Sbjct: 244  CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI 303

Query: 1183 RSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEH 1362
             SIR+DGND  AVY+A   AR  A+ E +P LIEAMTYR+GHHSTSDDS+ YR  DE+ +
Sbjct: 304  LSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY 363

Query: 1363 WRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVY 1542
            W     P+SR R  +Q  GWW   QE   R   R+++++A + AER  K   + +F+DVY
Sbjct: 364  WDKQDHPISRLRHHLQSRGWWDDEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLIFSDVY 423

Query: 1543 DQIPSNLRQQERSLLDTIKRHPAEYPAD 1626
             ++P+ LR+Q+ SL   ++ +   YP D
Sbjct: 424  QEMPAQLRKQQESLARHLQTYGEHYPLD 451

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>Q72GU1:ODBA_THET2 2-oxoisovalerate dehydrogenase subunit alpha - Thermus thermophilus|
            (strain HB27 / ATCC BAA-163 / DSM 7039)
          Length = 367

 Score =  221 bits (563), Expect = 8e-57
 Identities = 124/329 (37%), Positives = 181/329 (55%), Gaps = 1/329 (0%)
 Frame = +1

Query: 613  KMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEXXXXXXXXXXXXQ-DIVLPQYREPG 789
            ++Y +M+  +++D  +    R G+ SF   + G E              D V P YR+ G
Sbjct: 40   RLYRDMLAARMLDERYTILIRTGKTSFIAPAAGHEAAQVAIAHAIRPGFDWVFPYYRDHG 99

Query: 790  VLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYS 969
            + L  G  L+E   Q+   K D  KGRQMP H GS  LN+FTV+SPIA+ +P A GAA S
Sbjct: 100  LALALGIPLKELFGQMLATKADPNKGRQMPEHPGSKALNFFTVASPIASHVPPAAGAAIS 159

Query: 970  LKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSD 1149
            +K+ +    A+  FGDG TSEGD++A +NFAAV  AP +F C NN +AIS     Q  S 
Sbjct: 160  MKLLRTGQVAVCTFGDGATSEGDWYAGINFAAVQGAPAVFVCENNFYAISVDYRHQTHSP 219

Query: 1150 GVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDDS 1329
             +  +  A+GI    +DG D LA Y  V  A E A     P L+E   YR G HS++DD 
Sbjct: 220  TIADKAHAFGIPGYLVDGMDVLASYYVVKEAVERARRGEGPSLVELRVYRYGPHSSADDD 279

Query: 1330 TKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMPK 1509
            ++YRP +E+  WR  +DP+ R+R++++  G W    E  +R  +R EL + ++ AE    
Sbjct: 280  SRYRPKEEVAFWR-KKDPIPRFRRFLEARGLWNEEWEEDVREEIRAELERGLKEAEEAGP 338

Query: 1510 HGLAELFTDVYDQIPSNLRQQERSLLDTI 1596
                 +F DV+ + P +L +QE  L + +
Sbjct: 339  VPPEWMFADVFAEKPWHLLRQEALLKEEL 367

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>Q5SLR4:ODBA_THET8 2-oxoisovalerate dehydrogenase subunit alpha - Thermus thermophilus|
            (strain HB8 / ATCC 27634 / DSM 579)
          Length = 367

 Score =  218 bits (555), Expect = 7e-56
 Identities = 123/329 (37%), Positives = 180/329 (54%), Gaps = 1/329 (0%)
 Frame = +1

Query: 613  KMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEXXXXXXXXXXXXQ-DIVLPQYREPG 789
            ++Y +M+  +++D  +    R G+ SF   + G E              D V P YR+ G
Sbjct: 40   RLYRDMLAARMLDERYTILIRTGKTSFIAPAAGHEAAQVAIAHAIRPGFDWVFPYYRDHG 99

Query: 790  VLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYS 969
            + L  G  L+E   Q+   K D  KGRQMP H GS  LN+FTV+SPIA+ +P A GAA S
Sbjct: 100  LALALGIPLKELLGQMLATKADPNKGRQMPEHPGSKALNFFTVASPIASHVPPAAGAAIS 159

Query: 970  LKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSD 1149
            +K+ +    A+  FGDG TSEGD++A +NFAAV  AP +F   NN +AIS     Q  S 
Sbjct: 160  MKLLRTGQVAVCTFGDGATSEGDWYAGINFAAVQGAPAVFIAENNFYAISVDYRHQTHSP 219

Query: 1150 GVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDDS 1329
             +  +  A+GI    +DG D LA Y  V  A E A     P L+E   YR G HS++DD 
Sbjct: 220  TIADKAHAFGIPGYLVDGMDVLASYYVVKEAVERARRGEGPSLVELRVYRYGPHSSADDD 279

Query: 1330 TKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMPK 1509
            ++YRP +E+  WR  +DP+ R+R++++  G W    E  +R  +R EL + ++ AE    
Sbjct: 280  SRYRPKEEVAFWR-KKDPIPRFRRFLEARGLWNEEWEEDVREEIRAELERGLKEAEEAGP 338

Query: 1510 HGLAELFTDVYDQIPSNLRQQERSLLDTI 1596
                 +F DV+ + P +L +QE  L + +
Sbjct: 339  VPPEWMFEDVFAEKPWHLLRQEALLKEEL 367

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>Q9I1M2:ODBA_PSEAE 2-oxoisovalerate dehydrogenase subunit alpha - Pseudomonas aeruginosa|
          Length = 410

 Score =  217 bits (553), Expect = 1e-55
 Identities = 149/392 (38%), Positives = 204/392 (52%), Gaps = 17/392 (4%)
 Frame = +1

Query: 460  DFPGGKLSFVGEMNFLP------ESQTERINCYRVLDDDGGTIYNSRFQEVSKDLALKMY 621
            DF    LS  GE+   P      E+     +  RVLDDDG  +      ++S +  L+  
Sbjct: 23   DFSYLHLSPAGEVRKPPVDVEPAETSDLAYSLVRVLDDDGHAV-GPWNPQLSNEQLLRGM 81

Query: 622  SNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLW 801
              M+  ++ D     AQRQ ++SFY+   GEE             D+  P YR+ G+L+ 
Sbjct: 82   RAMLKTRLFDARMLTAQRQKKLSFYMQCLGEEAIATAHTLALRDGDMCFPTYRQQGILIT 141

Query: 802  RGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAVG--AAYSLK 975
            R + L +   QL  N+ D  KGRQ+PI Y S    +F++S  +ATQ  QAVG   A ++K
Sbjct: 142  REYPLVDMICQLLSNEADPLKGRQLPIMYSSKEAGFFSISGNLATQFIQAVGWGMASAIK 201

Query: 976  MDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTA-EQFRSDG 1152
             D + A A  + GDG T+E DFH AL FA V  AP+I    NN WAIST  A        
Sbjct: 202  GDTRIASA--WIGDGATAESDFHTALTFAHVYRAPVILNVVNNQWAISTFQAIAGGEGTT 259

Query: 1153 VVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDDST 1332
               RG   GI S+R+DGND LAVY+A   A E A     P LIE +TYR G HSTSDD +
Sbjct: 260  FANRGVGCGIASLRVDGNDFLAVYAASEWAAERARRNLGPSLIEWVTYRAGPHSTSDDPS 319

Query: 1333 KYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAE----- 1497
            KYRPAD+  ++    DP++R ++ + G G W   Q       +  E+L A + AE     
Sbjct: 320  KYRPADDWTNFPLG-DPIARLKRHMIGLGIWSEEQHEATHKALEAEVLAAQKQAESHGTL 378

Query: 1498 ---RMPKHGLAELFTDVYDQIPSNLRQQERSL 1584
               R+P    A +F DVY ++P +LR+Q + L
Sbjct: 379  IDGRVP--SAASMFEDVYAELPEHLRRQRQEL 408

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>P21873:ODPA_BACST Pyruvate dehydrogenase E1 component, alpha subunit - Bacillus|
            stearothermophilus (Geobacillus stearothermophilus)
          Length = 369

 Score =  216 bits (550), Expect = 2e-55
 Identities = 124/355 (34%), Positives = 194/355 (54%), Gaps = 1/355 (0%)
 Frame = +1

Query: 511  ESQTERINCYRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRIS 690
            E   E+   +++L+++G  +      E+S +   ++   MV  +I+D       RQGR+ 
Sbjct: 15   EKVAEQFPTFQILNEEGEVVNEEAMPELSDEQLKELMRRMVYTRILDQRSISLNRQGRLG 74

Query: 691  FYLTSNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGR 870
            FY  + G+E            +D +LP YR+   ++W G  L     Q F     +  G 
Sbjct: 75   FYAPTAGQEASQIASHFALEKEDFILPGYRDVPQIIWHGLPLY----QAFLFSRGHFHGN 130

Query: 871  QMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAA 1050
            Q+P       +N       I  Q  QA G A  LKM  KKA AITY GDGGTS+GDF+  
Sbjct: 131  QIP-----EGVNVLPPQIIIGAQYIQAAGVALGLKMRGKKAVAITYTGDGGTSQGDFYEG 185

Query: 1051 LNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSA 1230
            +NFA   +AP IF  +NN +AISTP  +Q  +  +  +  A GI  I++DG D LAVY+A
Sbjct: 186  INFAGAFKAPAIFVVQNNRFAISTPVEKQTVAKTLAQKAVAAGIPGIQVDGMDPLAVYAA 245

Query: 1231 VHTAREMAITEGRPILIEAMTYRVGHHSTS-DDSTKYRPADEMEHWRTARDPVSRYRKWV 1407
            V  ARE AI    P LIE + +R G H+ S DD T+YR + E+E+    +DP+ R+RK++
Sbjct: 246  VKAARERAINGEGPTLIETLCFRYGPHTMSGDDPTRYR-SKELENEWAKKDPLVRFRKFL 304

Query: 1408 QGNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
            +  G W   +E+ +    ++E+ +AI+ A+  PK  + +L + +++++P NL++Q
Sbjct: 305  EAKGLWSEEEENNVIEQAKEEIKEAIKKADETPKQKVTDLISIMFEELPFNLKEQ 359

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>P60090:ODPA_STAAW Pyruvate dehydrogenase E1 component subunit alpha - Staphylococcus|
            aureus (strain MW2)
          Length = 370

 Score =  213 bits (541), Expect = 3e-54
 Identities = 119/345 (34%), Positives = 186/345 (53%), Gaps = 1/345 (0%)
 Frame = +1

Query: 541  RVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEX 720
            ++LD++G  +      +++ +  +++   MV  +I+D       RQGR+ FY  + G+E 
Sbjct: 26   QILDENGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEA 85

Query: 721  XXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNR 900
                       +D +LP YR+   ++W G  L E     F     + KG Q P       
Sbjct: 86   SQLASQYALEKEDYILPGYRDVPQIIWHGLPLTE----AFLFSRGHFKGNQFP-----EG 136

Query: 901  LNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP 1080
            +N  +    I  Q  QA G A++LK   K A AITY GDGG+S+GDF+  +NFAA  +AP
Sbjct: 137  VNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAP 196

Query: 1081 MIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAIT 1260
             IF  +NN +AISTP ++Q  ++ +  +  A GI  I++DG D LAVY A   AR+ A+ 
Sbjct: 197  AIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVA 256

Query: 1261 EGRPILIEAMTYRVGHHS-TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQ 1437
               P LIE MTYR G H+   DD T+YR +DE   W   +DP+ R+RK+++  G W   +
Sbjct: 257  GEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWE-KKDPLVRFRKFLENKGLWNEDK 315

Query: 1438 ESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
            E+++    + ++  AI+ A+   K  +  L   +Y+ +P NL +Q
Sbjct: 316  ENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360

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>Q6GAC1:ODPA_STAAS Pyruvate dehydrogenase E1 component subunit alpha - Staphylococcus|
            aureus (strain MSSA476)
          Length = 370

 Score =  213 bits (541), Expect = 3e-54
 Identities = 119/345 (34%), Positives = 186/345 (53%), Gaps = 1/345 (0%)
 Frame = +1

Query: 541  RVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEX 720
            ++LD++G  +      +++ +  +++   MV  +I+D       RQGR+ FY  + G+E 
Sbjct: 26   QILDENGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEA 85

Query: 721  XXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNR 900
                       +D +LP YR+   ++W G  L E     F     + KG Q P       
Sbjct: 86   SQLASQYALEKEDYILPGYRDVPQIIWHGLPLTE----AFLFSRGHFKGNQFP-----EG 136

Query: 901  LNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP 1080
            +N  +    I  Q  QA G A++LK   K A AITY GDGG+S+GDF+  +NFAA  +AP
Sbjct: 137  VNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAP 196

Query: 1081 MIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAIT 1260
             IF  +NN +AISTP ++Q  ++ +  +  A GI  I++DG D LAVY A   AR+ A+ 
Sbjct: 197  AIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVA 256

Query: 1261 EGRPILIEAMTYRVGHHS-TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQ 1437
               P LIE MTYR G H+   DD T+YR +DE   W   +DP+ R+RK+++  G W   +
Sbjct: 257  GEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWE-KKDPLVRFRKFLENKGLWNEDK 315

Query: 1438 ESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
            E+++    + ++  AI+ A+   K  +  L   +Y+ +P NL +Q
Sbjct: 316  ENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360

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>Q820A6:ODPA_STAAN Pyruvate dehydrogenase E1 component subunit alpha - Staphylococcus|
            aureus (strain N315)
          Length = 370

 Score =  213 bits (541), Expect = 3e-54
 Identities = 119/345 (34%), Positives = 186/345 (53%), Gaps = 1/345 (0%)
 Frame = +1

Query: 541  RVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEX 720
            ++LD++G  +      +++ +  +++   MV  +I+D       RQGR+ FY  + G+E 
Sbjct: 26   QILDENGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEA 85

Query: 721  XXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNR 900
                       +D +LP YR+   ++W G  L E     F     + KG Q P       
Sbjct: 86   SQLASQYALEKEDYILPGYRDVPQIIWHGLPLTE----AFLFSRGHFKGNQFP-----EG 136

Query: 901  LNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP 1080
            +N  +    I  Q  QA G A++LK   K A AITY GDGG+S+GDF+  +NFAA  +AP
Sbjct: 137  VNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAP 196

Query: 1081 MIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAIT 1260
             IF  +NN +AISTP ++Q  ++ +  +  A GI  I++DG D LAVY A   AR+ A+ 
Sbjct: 197  AIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVA 256

Query: 1261 EGRPILIEAMTYRVGHHS-TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQ 1437
               P LIE MTYR G H+   DD T+YR +DE   W   +DP+ R+RK+++  G W   +
Sbjct: 257  GEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWE-KKDPLVRFRKFLENKGLWNEDK 315

Query: 1438 ESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
            E+++    + ++  AI+ A+   K  +  L   +Y+ +P NL +Q
Sbjct: 316  ENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360

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>P60089:ODPA_STAAM Pyruvate dehydrogenase E1 component subunit alpha - Staphylococcus|
            aureus (strain Mu50 / ATCC 700699)
          Length = 370

 Score =  213 bits (541), Expect = 3e-54
 Identities = 119/345 (34%), Positives = 186/345 (53%), Gaps = 1/345 (0%)
 Frame = +1

Query: 541  RVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEX 720
            ++LD++G  +      +++ +  +++   MV  +I+D       RQGR+ FY  + G+E 
Sbjct: 26   QILDENGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEA 85

Query: 721  XXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNR 900
                       +D +LP YR+   ++W G  L E     F     + KG Q P       
Sbjct: 86   SQLASQYALEKEDYILPGYRDVPQIIWHGLPLTE----AFLFSRGHFKGNQFP-----EG 136

Query: 901  LNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP 1080
            +N  +    I  Q  QA G A++LK   K A AITY GDGG+S+GDF+  +NFAA  +AP
Sbjct: 137  VNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAP 196

Query: 1081 MIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAIT 1260
             IF  +NN +AISTP ++Q  ++ +  +  A GI  I++DG D LAVY A   AR+ A+ 
Sbjct: 197  AIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVA 256

Query: 1261 EGRPILIEAMTYRVGHHS-TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQ 1437
               P LIE MTYR G H+   DD T+YR +DE   W   +DP+ R+RK+++  G W   +
Sbjct: 257  GEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWE-KKDPLVRFRKFLENKGLWNEDK 315

Query: 1438 ESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
            E+++    + ++  AI+ A+   K  +  L   +Y+ +P NL +Q
Sbjct: 316  ENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360

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>Q5HGZ1:ODPA_STAAC Pyruvate dehydrogenase E1 component subunit alpha - Staphylococcus|
            aureus (strain COL)
          Length = 370

 Score =  213 bits (541), Expect = 3e-54
 Identities = 119/345 (34%), Positives = 186/345 (53%), Gaps = 1/345 (0%)
 Frame = +1

Query: 541  RVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEX 720
            ++LD++G  +      +++ +  +++   MV  +I+D       RQGR+ FY  + G+E 
Sbjct: 26   QILDENGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEA 85

Query: 721  XXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNR 900
                       +D +LP YR+   ++W G  L E     F     + KG Q P       
Sbjct: 86   SQLASQYALEKEDYILPGYRDVPQIIWHGLPLTE----AFLFSRGHFKGNQFP-----EG 136

Query: 901  LNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP 1080
            +N  +    I  Q  QA G A++LK   K A AITY GDGG+S+GDF+  +NFAA  +AP
Sbjct: 137  VNALSPQIIIGAQYIQAAGVAFALKKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAP 196

Query: 1081 MIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAIT 1260
             IF  +NN +AISTP ++Q  ++ +  +  A GI  I++DG D LAVY A   AR+ A+ 
Sbjct: 197  AIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVA 256

Query: 1261 EGRPILIEAMTYRVGHHS-TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQ 1437
               P LIE MTYR G H+   DD T+YR +DE   W   +DP+ R+RK+++  G W   +
Sbjct: 257  GEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWE-KKDPLVRFRKFLENKGLWNEDK 315

Query: 1438 ESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
            E+++    + ++  AI+ A+   K  +  L   +Y+ +P NL +Q
Sbjct: 316  ENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360

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>P21881:ODPA_BACSU Pyruvate dehydrogenase E1 component subunit alpha - Bacillus subtilis|
          Length = 371

 Score =  211 bits (538), Expect = 6e-54
 Identities = 119/351 (33%), Positives = 189/351 (53%), Gaps = 1/351 (0%)
 Frame = +1

Query: 523  ERINCYRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLT 702
            ++   +++L++ G  +  +   +++ D   ++   MV  +++D       RQGR+ FY  
Sbjct: 21   KQFETFQILNEKGEVVNEAAMPDLTDDQLKELMRRMVFTRVLDQRSISLNRQGRLGFYAP 80

Query: 703  SNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPI 882
            + G+E            +D VLP YR+   L+W G  L     Q F     + +G QMP 
Sbjct: 81   TAGQEASQIATHFALEKEDFVLPGYRDVPQLIWHGLPLY----QAFLFSRGHFRGNQMP- 135

Query: 883  HYGSNRLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFA 1062
                + +N  +    I  Q  Q  G A  LK   KKA AITY GDGG S+GDF+  +NFA
Sbjct: 136  ----DDVNALSPQIIIGAQYIQTAGVALGLKKRGKKAVAITYTGDGGASQGDFYEGINFA 191

Query: 1063 AVAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTA 1242
               +AP IF  +NN +AISTP  +Q  ++ +  +  A GI  +++DG D LAVY+A   A
Sbjct: 192  GAYKAPAIFVVQNNRYAISTPVEKQSAAETIAQKAVAAGIVGVQVDGMDPLAVYAATAEA 251

Query: 1243 REMAITEGRPILIEAMTYRVGHHS-TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNG 1419
            RE AI    P LIE +T+R G H+   DD TKYR  +    W   +DP+ R+R +++  G
Sbjct: 252  RERAINGEGPTLIETLTFRYGPHTMAGDDPTKYRTKEIENEWE-QKDPLVRFRAFLENKG 310

Query: 1420 WWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
             W   +E+++  + ++E+ QAI+ A+  PK  + +L   +Y+++P NL +Q
Sbjct: 311  LWSEEEEAKVIEDAKEEIKQAIKKADAEPKQKVTDLMKIMYEKMPHNLEEQ 361

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>Q8CPN3:ODPA_STAES Pyruvate dehydrogenase E1 component subunit alpha - Staphylococcus|
            epidermidis (strain ATCC 12228)
          Length = 370

 Score =  211 bits (537), Expect = 8e-54
 Identities = 119/357 (33%), Positives = 191/357 (53%), Gaps = 1/357 (0%)
 Frame = +1

Query: 505  LPESQTERINCYRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGR 684
            L E+Q+ +    ++LD+DG  +      +++ +  +++   MV  +I+D       RQGR
Sbjct: 15   LNETQS-KFEMVQILDEDGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGR 73

Query: 685  ISFYLTSNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGK 864
            + FY  + G+E            +D +LP YR+   ++W G  L +     F     + K
Sbjct: 74   LGFYAPTAGQEASQLASQYALESEDFILPGYRDVPQIIWHGLPLTD----AFLFSRGHFK 129

Query: 865  GRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFH 1044
            G Q P       +N  +    I  Q  Q  G A+ LK   K A AITY GDGG+S+GDF+
Sbjct: 130  GNQFP-----EGVNALSPQIIIGAQYIQTAGVAFGLKKRGKNAVAITYTGDGGSSQGDFY 184

Query: 1045 AALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVY 1224
              +NFA+  +AP IF  +NN +AISTP ++Q  ++ +  +  + GI  I++DG D LAVY
Sbjct: 185  EGINFASAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAISVGIPGIQVDGMDALAVY 244

Query: 1225 SAVHTAREMAITEGRPILIEAMTYRVGHHS-TSDDSTKYRPADEMEHWRTARDPVSRYRK 1401
             A   ARE A+    P +IE +TYR G H+   DD T+YR +DE   W   +DP+ R+RK
Sbjct: 245  QATLEARERAVAGEGPTVIETLTYRYGPHTMAGDDPTRYRTSDEDAEWE-KKDPLVRFRK 303

Query: 1402 WVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
            +++  G W   +E+++    + E+  AI+ A+   K  +  L   +Y+++P NL +Q
Sbjct: 304  YLEAKGLWNEDKENEVVERAKSEIKAAIKEADNTEKQTVTSLMDIMYEEMPQNLAEQ 360

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>Q5HQ76:ODPA_STAEQ Pyruvate dehydrogenase E1 component subunit alpha - Staphylococcus|
            epidermidis (strain ATCC 35984 / RP62A)
          Length = 370

 Score =  211 bits (537), Expect = 8e-54
 Identities = 119/357 (33%), Positives = 191/357 (53%), Gaps = 1/357 (0%)
 Frame = +1

Query: 505  LPESQTERINCYRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGR 684
            L E+Q+ +    ++LD+DG  +      +++ +  +++   MV  +I+D       RQGR
Sbjct: 15   LNETQS-KFEMVQILDEDGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGR 73

Query: 685  ISFYLTSNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGK 864
            + FY  + G+E            +D +LP YR+   ++W G  L +     F     + K
Sbjct: 74   LGFYAPTAGQEASQLASQYALESEDFILPGYRDVPQIIWHGLPLTD----AFLFSRGHFK 129

Query: 865  GRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFH 1044
            G Q P       +N  +    I  Q  Q  G A+ LK   K A AITY GDGG+S+GDF+
Sbjct: 130  GNQFP-----EGVNALSPQIIIGAQYIQTAGVAFGLKKRGKNAVAITYTGDGGSSQGDFY 184

Query: 1045 AALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVY 1224
              +NFA+  +AP IF  +NN +AISTP ++Q  ++ +  +  + GI  I++DG D LAVY
Sbjct: 185  EGINFASAYKAPAIFVIQNNNYAISTPRSKQTAAETLAQKAISVGIPGIQVDGMDALAVY 244

Query: 1225 SAVHTAREMAITEGRPILIEAMTYRVGHHS-TSDDSTKYRPADEMEHWRTARDPVSRYRK 1401
             A   ARE A+    P +IE +TYR G H+   DD T+YR +DE   W   +DP+ R+RK
Sbjct: 245  QATLEARERAVAGEGPTVIETLTYRYGPHTMAGDDPTRYRTSDEDAEWE-KKDPLVRFRK 303

Query: 1402 WVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
            +++  G W   +E+++    + E+  AI+ A+   K  +  L   +Y+++P NL +Q
Sbjct: 304  YLEAKGLWNEDKENEVVERAKSEIKAAIKEADNTEKQTVTSLMDIMYEEMPQNLAEQ 360

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>Q6GHZ2:ODPA_STAAR Pyruvate dehydrogenase E1 component subunit alpha - Staphylococcus|
            aureus (strain MRSA252)
          Length = 370

 Score =  211 bits (537), Expect = 8e-54
 Identities = 118/345 (34%), Positives = 185/345 (53%), Gaps = 1/345 (0%)
 Frame = +1

Query: 541  RVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEX 720
            ++LD++G  +      +++ +  +++   MV  +I+D       RQGR+ FY  + G+E 
Sbjct: 26   QILDENGNVVNEDLVPDLTDEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEA 85

Query: 721  XXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNR 900
                       +D +LP YR+   ++W G  L E     F     + KG Q P       
Sbjct: 86   SQLASQYALEKEDYILPGYRDVPQIIWHGLPLTE----AFLFSRGHFKGNQFP-----EG 136

Query: 901  LNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP 1080
            +N  +    I  Q  Q  G A++LK   K A AITY GDGG+S+GDF+  +NFAA  +AP
Sbjct: 137  VNALSPQIIIGAQYIQTAGVAFALKKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAP 196

Query: 1081 MIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAIT 1260
             IF  +NN +AISTP ++Q  ++ +  +  A GI  I++DG D LAVY A   AR+ A+ 
Sbjct: 197  AIFVIQNNNYAISTPRSKQTAAETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVA 256

Query: 1261 EGRPILIEAMTYRVGHHS-TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQ 1437
               P LIE MTYR G H+   DD T+YR +DE   W   +DP+ R+RK+++  G W   +
Sbjct: 257  GEGPTLIETMTYRYGPHTMAGDDPTRYRTSDEDAEWE-KKDPLVRFRKFLENKGLWNEDK 315

Query: 1438 ESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
            E+++    + ++  AI+ A+   K  +  L   +Y+ +P NL +Q
Sbjct: 316  ENEVIERAKADIKAAIKEADNTEKQTVTSLMEIMYEDMPQNLAEQ 360

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>Q4MTG0:ODPA_BACCE Pyruvate dehydrogenase E1 component, alpha subunit - Bacillus cereus|
          Length = 371

 Score =  207 bits (527), Expect = 1e-52
 Identities = 118/345 (34%), Positives = 181/345 (52%), Gaps = 1/345 (0%)
 Frame = +1

Query: 541  RVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEX 720
            ++L++ G  +  +   E+S D   ++   MV  +++D       RQGR+ FY  + G+E 
Sbjct: 27   QILNEKGEVVNEAAMPELSDDQLKELMRRMVYTRVLDQRSISLNRQGRLGFYAPTAGQEA 86

Query: 721  XXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNR 900
                       +D +LP YR+   L+W G  L     Q F     +  G QMP       
Sbjct: 87   SQLASHFALEAEDFILPGYRDVPQLVWHGLPLY----QAFLFSRGHFMGNQMP-----EN 137

Query: 901  LNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP 1080
            +N       I  Q+ Q  G A  +K+  KK+ AITY GDGG S+GDF+  +NFA   +AP
Sbjct: 138  VNALAPQIIIGAQIIQTAGVALGMKLRGKKSVAITYTGDGGASQGDFYEGMNFAGAFKAP 197

Query: 1081 MIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAIT 1260
             IF  +NN +AISTP  +Q  +  V  +  A GI  I++DG D LAVY+A   ARE A+ 
Sbjct: 198  AIFVVQNNRYAISTPVEKQSAAKTVAQKAVAAGIYGIQVDGMDPLAVYAATAFARERAVN 257

Query: 1261 EGRPILIEAMTYRVGHHS-TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQ 1437
               P LIE +T+R G H+   DD T+YR  D    W   +DP+ R+R +++  G W    
Sbjct: 258  GEGPTLIETLTFRYGPHTMAGDDPTRYRTKDIENEWE-QKDPIVRFRAFLENKGLWSQEV 316

Query: 1438 ESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQ 1572
            E ++    ++++ QAI  A++ PK  + +L   +Y+++P NL +Q
Sbjct: 317  EEKVIEEAKEDIKQAIAKADQAPKQKVTDLMEIMYEKMPYNLAEQ 361

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>P09060:ODBA_PSEPU 2-oxoisovalerate dehydrogenase subunit alpha - Pseudomonas putida|
          Length = 410

 Score =  203 bits (517), Expect = 2e-51
 Identities = 131/355 (36%), Positives = 182/355 (51%), Gaps = 7/355 (1%)
 Frame = +1

Query: 541  RVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEX 720
            RVLD+ G        +++   +  +    M+  +I D+    AQRQ ++SFY+ S GEE 
Sbjct: 56   RVLDEQGDA-QGPWAEDIDPQILRQGMRAMLKTRIFDSRMVVAQRQKKMSFYMQSLGEEA 114

Query: 721  XXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNR 900
                        D+  P YR+  +L+ R  +L E   QL  N+ D  KGRQ+PI Y    
Sbjct: 115  IGSGQALALNRTDMCFPTYRQQSILMARDVSLVEMICQLLSNERDPLKGRQLPIMYSVRE 174

Query: 901  LNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP 1080
              +FT+S  +ATQ  QAVG A +  +      A  + GDG T+E DFH AL FA V  AP
Sbjct: 175  AGFFTISGNLATQFVQAVGWAMASAIKGDTKIASAWIGDGATAESDFHTALTFAHVYRAP 234

Query: 1081 MIFFCRNNGWAISTPTA-EQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAI 1257
            +I    NN WAIST  A     S     RG   GI S+R+DGND +AVY+A   A E A 
Sbjct: 235  VILNVVNNQWAISTFQAIAGGESTTFAGRGVGCGIASLRVDGNDFVAVYAASRWAAERAR 294

Query: 1258 TEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQ 1437
                P LIE +TYR G HSTSDD +KYRPAD+  H+    DP++R ++ +   G W   +
Sbjct: 295  RGLGPSLIEWVTYRAGPHSTSDDPSKYRPADDWSHFPLG-DPIARLKQHLIKIGHWSEEE 353

Query: 1438 ESQLRNNVRQELLQAIQVAERMPK------HGLAELFTDVYDQIPSNLRQQERSL 1584
                       ++ A + AE+            A +F DVY ++P +LR+Q + L
Sbjct: 354  HQATTAEFEAAVIAAQKEAEQYGTLANGHIPSAASMFEDVYKEMPDHLRRQRQEL 408

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>P37940:ODBA_BACSU 2-oxoisovalerate dehydrogenase subunit alpha - Bacillus subtilis|
          Length = 330

 Score =  186 bits (472), Expect = 3e-46
 Identities = 107/302 (35%), Positives = 161/302 (53%), Gaps = 2/302 (0%)
 Frame = +1

Query: 607  ALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEXXXXXXXXXXXXQ-DIVLPQYRE 783
            A+ MY  M+  + +D   +   R G+I F ++  G+E            + D VLP YR+
Sbjct: 16   AVDMYRTMLLARKIDERMWLLNRSGKIPFVISCQGQEAAQVGAAFALDREMDYVLPYYRD 75

Query: 784  PGVLLWRGFTLQEFANQLFGNKLDYGKG-RQMPIHYGSNRLNYFTVSSPIATQLPQAVGA 960
             GV+L  G T ++     F    D   G RQMP H+G  +    T SSP+ TQ+P AVG 
Sbjct: 76   MGVVLAFGMTAKDLMMSGFAKAADPNSGGRQMPGHFGQKKNRIVTGSSPVTTQVPHAVGI 135

Query: 961  AYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQF 1140
            A + +M+KK   A   FG+G +++GDFH   NFAAV + P+IF C NN +AIS P  +Q 
Sbjct: 136  ALAGRMEKKDIAAFVTFGEGSSNQGDFHEGANFAAVHKLPVIFMCENNKYAISVPYDKQV 195

Query: 1141 RSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTS 1320
              + +  R   YG+  + ++GND L VY AV  ARE A     P LIE ++YR+  HS+ 
Sbjct: 196  ACENISDRAIGYGMPGVTVNGNDPLEVYQAVKEARERARRGEGPTLIETISYRLTPHSSD 255

Query: 1321 DDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAER 1500
            DD + YR  +E+E  + + DP+  Y+ +++  G      E  + + +   + +A   AE 
Sbjct: 256  DDDSSYRGREEVEEAKKS-DPLLTYQAYLKETGLLSDEIEQTMLDEIMAIVNEATDEAEN 314

Query: 1501 MP 1506
             P
Sbjct: 315  AP 316

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>P35485:ODPA_ACHLA Pyruvate dehydrogenase E1 component subunit alpha - Acholeplasma|
            laidlawii
          Length = 345

 Score =  169 bits (428), Expect = 3e-41
 Identities = 110/343 (32%), Positives = 169/343 (49%), Gaps = 3/343 (0%)
 Frame = +1

Query: 553  DDGGTIYNSRFQ-EVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEEXXXX 729
            D  G + N + + ++ K+  LKMY   V  +  D    + QRQGR+  Y  + G+E    
Sbjct: 1    DQNGKVVNEKMEPKLPKETLLKMYKTAVLGRNADIKALQYQRQGRMLTYAPNMGQEAAQI 60

Query: 730  XXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNY 909
                    QD   P YRE   LL+RG  L+      +GN+    +G   P       +  
Sbjct: 61   GMAAAMEPQDWNSPMYRELNTLLYRGDKLENVFLYWYGNE----RGSIKP-----EGVKI 111

Query: 910  FTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIF 1089
               +  I +Q   A G A + K+ K         GDGGT+ G+F+  LNFAA  +AP++ 
Sbjct: 112  LPTNIIIGSQSNIAAGLAMASKIRKTNEVTAFTIGDGGTAHGEFYEGLNFAASFKAPVVA 171

Query: 1090 FCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGR 1269
              +NN WAISTP  +   S+ +  +G A+GI  I++DGND LA+Y A   A + A     
Sbjct: 172  VIQNNQWAISTPVRKASNSETLAQKGVAFGIPYIQVDGNDMLAMYVASKEAMDRARKGDG 231

Query: 1270 PILIEAMTYRVGHHSTSDDSTK-YRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQ 1446
            P LIEA TYR+G H+TSDD    YR  +E   W   +D ++R++ ++   G+W   ++ +
Sbjct: 232  PTLIEAFTYRMGPHTTSDDPCSIYRTKEEENEW-AKKDQIARFKTYLINKGYWSEEEDKK 290

Query: 1447 LRNNVRQELLQAIQVAERMPKH-GLAELFTDVYDQIPSNLRQQ 1572
            L   V  E+    +  E    +  L E+F   Y ++   L++Q
Sbjct: 291  LEEEVLAEINDTFKKVESYGANVELIEIFEHTYAEMTPQLKEQ 333

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>P26268:ODPT_ASCSU Pyruvate dehydrogenase E1 component alpha subunit type II,|
            mitochondrial precursor - Ascaris suum (Pig roundworm)
            (Ascaris lumbricoides)
          Length = 391

 Score =  143 bits (361), Expect = 2e-33
 Identities = 95/327 (29%), Positives = 157/327 (48%), Gaps = 5/327 (1%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            V+K+ AL+ Y+ M T++ M+T      ++ ++  F    +G+E             D  +
Sbjct: 47   VTKEDALRYYTQMQTIRRMETAAGNLYKEKKVRGFCHLYSGQEACAVGMKAAMEPGDAAI 106

Query: 769  PQYREPGVLLWRGF----TLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIAT 936
              YR  G     G      L E   ++ GN   YGKG  M + YG N   ++  +  +  
Sbjct: 107  TAYRCHGWTYLSGSPVAKVLCELTGRITGNV--YGKGGSMHM-YGEN---FYGGNGIVGA 160

Query: 937  QLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAI 1116
            Q P   G A+++K  K+K   IT FGDG T++G  + ++N A + E P+++ C NNG+ +
Sbjct: 161  QQPLGTGIAFAMKYKKQKNVCITLFGDGATNQGQLYESMNMAKLWELPVLYVCENNGYGM 220

Query: 1117 STPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTY 1296
             T  A    S    TRG    +    +DG D LAV  A+   +E       P++IE  TY
Sbjct: 221  GTSAARSSASTDYYTRGDY--VPGFWVDGMDVLAVRQAIRWGKEWCNAGKGPLMIEMATY 278

Query: 1297 RVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELL 1476
            R G HS SD  T YR  +E++  R  RDP++ ++  +   G     +  ++   +R+E+ 
Sbjct: 279  RYGGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDKIVTAGLVTEDELKEVDKEIRKEVD 338

Query: 1477 QAIQVAERMPKHGLAELFTDVYDQIPS 1557
             A++ A    +  +  L TD+Y   P+
Sbjct: 339  AAVKQAHTDKEAPVEMLLTDIYYNTPA 365

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>P75390:ODPA_MYCPN Pyruvate dehydrogenase E1 component subunit alpha - Mycoplasma|
            pneumoniae
          Length = 358

 Score =  143 bits (360), Expect = 3e-33
 Identities = 102/346 (29%), Positives = 163/346 (47%)
 Frame = +1

Query: 538  YRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEE 717
            Y+V D++G  +  +    +S +     +  M   +IMD      QR G++  +  + GEE
Sbjct: 14   YQVYDNEGKLMDPNHKITLSNEQLKHAFYLMNLSRIMDKKMLVWQRAGKMLNFAPNLGEE 73

Query: 718  XXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSN 897
                         D   P +R   ++L+RG   ++      GN+     G ++   Y + 
Sbjct: 74   ALQVGMGMGLNENDWFCPTFRSGALMLYRGVKPEQLLLYWNGNE----NGSKIEAKYKTL 129

Query: 898  RLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEA 1077
             +N       I  Q   A G  Y L   K    A+T  GDGGT+EG+F+ A+N A++ + 
Sbjct: 130  PINI-----TIGAQYSHAAGLGYMLHYKKLPNVAVTMIGDGGTAEGEFYEAMNIASIHKW 184

Query: 1078 PMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAI 1257
              +F   NN +AIST T  +     + T+  A  I  IR+DGND +A Y A+H A   A 
Sbjct: 185  NSVFCINNNQFAISTRTKLESAVSDLSTKAIAVNIPRIRVDGNDLIASYEAMHEAANYAR 244

Query: 1258 TEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQ 1437
            +   P+LIE  ++R G H+TSDD + YR  +E E      DPV R R ++   G     Q
Sbjct: 245  SGNGPVLIEFFSWRQGPHTTSDDPSIYRTKEE-EAEAMKSDPVKRLRNFLFDRGILTPQQ 303

Query: 1438 ESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQE 1575
            E ++   + QE+  A +V        L E+F   Y+++  +L +Q+
Sbjct: 304  EEEMVAKIEQEVQAAYEVMVSKTPVTLDEVFDYNYEKLTPDLARQK 349

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>P47516:ODPA_MYCGE Pyruvate dehydrogenase E1 component subunit alpha - Mycoplasma|
            genitalium
          Length = 358

 Score =  142 bits (357), Expect = 6e-33
 Identities = 101/347 (29%), Positives = 162/347 (46%)
 Frame = +1

Query: 538  YRVLDDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRISFYLTSNGEE 717
            Y+V D++G  I  +    ++ +     Y  M   ++MD      QR G++  +  + GEE
Sbjct: 14   YQVYDNEGKLIDPNHKITLTDEQLKHAYYLMNLSRMMDKKMLVWQRAGKMLNFAPNLGEE 73

Query: 718  XXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSN 897
                         D V P +R   ++L+RG   ++      GN+    KG Q+   Y + 
Sbjct: 74   ALQVGMGLGLNENDWVCPTFRSGALMLYRGVKPEQLLLYWNGNE----KGSQIDAKYKTL 129

Query: 898  RLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEA 1077
             +N       I  Q   A G  Y L   K+   A+T  GDGGT+EG+F+ A+N A++ + 
Sbjct: 130  PINI-----TIGAQYSHAAGLGYMLHYKKQPNVAVTMIGDGGTAEGEFYEAMNIASIHKW 184

Query: 1078 PMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAI 1257
              +F   NN +AIST T  +     +  +  A GI  +R+DGND +A Y A+  A   A 
Sbjct: 185  NTVFCINNNQFAISTRTKLESAVSDLSVKAIACGIPRVRVDGNDLIASYEAMQDAANYAR 244

Query: 1258 TEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQ 1437
                P+LIE  +YR G H+TSDD + YR   E E    + DPV R R ++         Q
Sbjct: 245  GGNGPVLIEFFSYRQGPHTTSDDPSIYRTKQEEEEGMKS-DPVKRLRNFLFDRSILNQAQ 303

Query: 1438 ESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVYDQIPSNLRQQER 1578
            E ++ + + QE+  A +         + E+F   Y ++   L +Q++
Sbjct: 304  EEEMFSKIEQEIQAAYEKMVLDTPVSVDEVFDYNYQELTPELVEQKQ 350

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>P52901:ODPA1_ARATH Pyruvate dehydrogenase E1 component subunit alpha-1, mitochondrial|
            precursor - Arabidopsis thaliana (Mouse-ear cress)
          Length = 389

 Score =  140 bits (353), Expect = 2e-32
 Identities = 91/326 (27%), Positives = 154/326 (47%), Gaps = 4/326 (1%)
 Frame = +1

Query: 577  SRFQEVSKDLALKMYSNMVTLQIM----DTIFYEAQRQGRISFYLTSNGEEXXXXXXXXX 744
            SR  E S    L  +  M  ++ M    D+++     +G    Y   +G+E         
Sbjct: 49   SRSVESSSQELLDFFRTMALMRRMEIAADSLYKAKLIRGFCHLY---DGQEAVAIGMEAA 105

Query: 745  XXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSS 924
               +D ++  YR+  + L RG +L E  ++L G +    KG+   +H+     +++    
Sbjct: 106  ITKKDAIITAYRDHCIFLGRGGSLHEVFSELMGRQAGCSKGKGGSMHFYKKESSFYGGHG 165

Query: 925  PIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNN 1104
             +  Q+P   G A++ K +K++A     +GDG  ++G    ALN +A+ + P I  C NN
Sbjct: 166  IVGAQVPLGCGIAFAQKYNKEEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENN 225

Query: 1105 GWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIE 1284
             + + T      +S     RG    +  +++DG D  AV  A   A++ A+ +G PI++E
Sbjct: 226  HYGMGTAEWRAAKSPSYYKRGDY--VPGLKVDGMDAFAVKQACKFAKQHALEKG-PIILE 282

Query: 1285 AMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVR 1464
              TYR   HS SD  + YR  DE+   R  RDP+ R +K V  +      +   +   +R
Sbjct: 283  MDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIR 342

Query: 1465 QELLQAIQVAERMPKHGLAELFTDVY 1542
            +E+  AI  A+  P    +ELFT+VY
Sbjct: 343  KEVDDAIAKAKDCPMPEPSELFTNVY 368

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>Q8H1Y0:ODPA2_ARATH Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial|
            precursor - Arabidopsis thaliana (Mouse-ear cress)
          Length = 393

 Score =  140 bits (352), Expect = 2e-32
 Identities = 90/326 (27%), Positives = 153/326 (46%), Gaps = 4/326 (1%)
 Frame = +1

Query: 577  SRFQEVSKDLALKMYSNMVTLQIM----DTIFYEAQRQGRISFYLTSNGEEXXXXXXXXX 744
            SR  E S +  L  + +M  ++ M    D+++     +G    Y   +G+E         
Sbjct: 53   SRSVETSSEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLY---DGQEALAVGMEAA 109

Query: 745  XXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSS 924
               +D ++  YR+    + RG  L +  ++L G K     G+   +H+     +++    
Sbjct: 110  ITKKDAIITSYRDHCTFIGRGGKLVDAFSELMGRKTGCSHGKGGSMHFYKKDASFYGGHG 169

Query: 925  PIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNN 1104
             +  Q+P   G A++ K +K +A     +GDG  ++G    ALN +A+ + P I  C NN
Sbjct: 170  IVGAQIPLGCGLAFAQKYNKDEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENN 229

Query: 1105 GWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIE 1284
             + + T T    +S     RG    +  +++DG D LAV  A   A+E A+  G PI++E
Sbjct: 230  HYGMGTATWRSAKSPAYFKRGDY--VPGLKVDGMDALAVKQACKFAKEHALKNG-PIILE 286

Query: 1285 AMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVR 1464
              TYR   HS SD  + YR  DE+   R  RDP+ R RK +  +      +   +   +R
Sbjct: 287  MDTYRYHGHSMSDPGSTYRTRDEISGVRQVRDPIERVRKLLLTHDIATEKELKDMEKEIR 346

Query: 1465 QELLQAIQVAERMPKHGLAELFTDVY 1542
            +E+  A+  A+  P    +ELFT++Y
Sbjct: 347  KEVDDAVAQAKESPIPDASELFTNMY 372

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>P26267:ODPA_ASCSU Pyruvate dehydrogenase E1 component alpha subunit type I,|
            mitochondrial precursor - Ascaris suum (Pig roundworm)
            (Ascaris lumbricoides)
          Length = 396

 Score =  139 bits (351), Expect = 3e-32
 Identities = 94/327 (28%), Positives = 158/327 (48%), Gaps = 5/327 (1%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            V+K+ A+  Y+ M+T++ M++      ++ ++  F    +G+E             D  +
Sbjct: 52   VTKEDAVHYYTQMLTIRRMESAAGNLYKEKKVRGFCHLYSGQEACAVGTKAAMDAGDAAV 111

Query: 769  PQYREPGVLLWRGFT----LQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIAT 936
              YR  G     G +    L E   ++ GN   YGKG  M + YG N   ++  +  +  
Sbjct: 112  TAYRCHGWTYLSGSSVAKVLCELTGRITGNV--YGKGGSMHM-YGEN---FYGGNGIVGA 165

Query: 937  QLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAI 1116
            Q P   G A+++K  K+K   IT FGDG T++G    ++N A + + P+++ C NNG+ +
Sbjct: 166  QQPLGTGIAFAMKYRKEKNVCITMFGDGATNQGQLFESMNMAKLWDLPVLYVCENNGYGM 225

Query: 1117 STPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTY 1296
             T  A    S    TRG    +  I +DG D LAV  AV  A+E       P++IE  TY
Sbjct: 226  GTAAARSSASTDYYTRGDY--VPGIWVDGMDVLAVRQAVRWAKEWCNAGKGPLMIEMATY 283

Query: 1297 RVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELL 1476
            R   HS SD  T YR  +E++  R  RDP++ ++  +   G     +  ++   VR+E+ 
Sbjct: 284  RYSGHSMSDPGTSYRTREEVQEVRKTRDPITGFKDKIVTAGLVTEDEIKEIDKQVRKEID 343

Query: 1477 QAIQVAERMPKHGLAELFTDVYDQIPS 1557
             A++ A    +  +  + TD+Y   P+
Sbjct: 344  AAVKQAHTDKESPVELMLTDIYYNTPA 370

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>P16387:ODPA_YEAST Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial|
            precursor - Saccharomyces cerevisiae (Baker's yeast)
          Length = 420

 Score =  135 bits (339), Expect = 7e-31
 Identities = 90/327 (27%), Positives = 156/327 (47%), Gaps = 9/327 (2%)
 Frame = +1

Query: 589  EVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIV 765
            E SK   L+MY +MV ++ M+       +  +I  F   S G+E             D +
Sbjct: 75   ETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAIAVGIENAITKLDSI 134

Query: 766  LPQYREPGVLLWRGFTLQEFANQLFGNK--LDYGKGRQMPIH----YGSNRLNYFTVSSP 927
            +  YR  G    RG +++    +L G +  + YGKG  M ++    YG N +        
Sbjct: 135  ITSYRCHGFTFMRGASVKAVLAELMGRRAGVSYGKGGSMHLYAPGFYGGNGI-------- 186

Query: 928  IATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNG 1107
            +  Q+P   G A++ +   + AC+ T +GDG +++G    + N A +   P++F C NN 
Sbjct: 187  VGAQVPLGAGLAFAHQYKNEDACSFTLYGDGASNQGQVFESFNMAKLWNLPVVFCCENNK 246

Query: 1108 WAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEA 1287
            + + T  +          RGQ   I  ++++G D LAVY A   A++  ++   P+++E 
Sbjct: 247  YGMGTAASRSSAMTEYFKRGQY--IPGLKVNGMDILAVYQASKFAKDWCLSGKGPLVLEY 304

Query: 1288 MTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQ 1467
             TYR G HS SD  T YR  DE++H R+  DP++  +  +   G     +      + R+
Sbjct: 305  ETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLIDLGIATEAEVKAYDKSARK 364

Query: 1468 ELLQAIQVAERM--PKHGLAELFTDVY 1542
             + + +++A+    P+  L+ LF DVY
Sbjct: 365  YVDEQVELADAAPPPEAKLSILFEDVY 391

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>P52903:ODPA_SOLTU Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial|
            precursor - Solanum tuberosum (Potato)
          Length = 391

 Score =  133 bits (334), Expect = 3e-30
 Identities = 90/326 (27%), Positives = 148/326 (45%), Gaps = 4/326 (1%)
 Frame = +1

Query: 577  SRFQEVSKDLALKMYSNMVTLQIM----DTIFYEAQRQGRISFYLTSNGEEXXXXXXXXX 744
            SR  E S    +  + +M  ++ M    D+++     +G    Y   +G+E         
Sbjct: 51   SRSVETSPKELMTFFKDMTEMRRMEIAADSLYKAKLIRGFCHLY---DGQEAVAVGMEAA 107

Query: 745  XXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSS 924
               +D ++  YR+  + L RG TL E   +L G +    +G+   +H+      ++    
Sbjct: 108  ITKKDCIITAYRDHCIFLGRGGTLVEAFAELMGRRDGCSRGKGGSMHFYKKESGFYGGHG 167

Query: 925  PIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNN 1104
             +  Q+P  +G A++ K  K+       +GDG  ++G    ALN AA+ + P I  C NN
Sbjct: 168  IVGAQVPLGIGLAFAQKYKKEDYVTFAMYGDGAANQGQLFEALNMAALWDLPAILVCENN 227

Query: 1105 GWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIE 1284
             + + T      +S     RG    +  +R+DG D  AV  A   A++ A+  G PI++E
Sbjct: 228  HYGMGTAEWRAAKSPAYYKRGDY--VPGLRVDGMDVFAVKQACTFAKQHALKNG-PIILE 284

Query: 1285 AMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVR 1464
              TYR   HS SD  + YR  DE+   R  RDPV R R  +  +      +   +    R
Sbjct: 285  MDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPVERIRSLILAHNIATEAELKDIEKENR 344

Query: 1465 QELLQAIQVAERMPKHGLAELFTDVY 1542
            + + +AI  A+  P    +ELFT+VY
Sbjct: 345  KVVDEAIAKAKESPMPDPSELFTNVY 370

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>Q1XDM0:ODPA_PORYE Pyruvate dehydrogenase E1 component subunit alpha - Porphyra|
            yezoensis
          Length = 346

 Score =  133 bits (334), Expect = 3e-30
 Identities = 98/329 (29%), Positives = 153/329 (46%), Gaps = 8/329 (2%)
 Frame = +1

Query: 565  TIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXX 741
            T YNS    ++K   L +Y +M+  +  + +  +   +G++  F    NG+E        
Sbjct: 12   TNYNSTGLNLNKSNLLVLYEDMLLGRNFEDMCAQMYYKGKMFGFVHLYNGQEAVSTGVIK 71

Query: 742  XXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVS 921
                 D V   YR+    L +G   +    +LFG +    KGR   +H  S   N+    
Sbjct: 72   LLNPTDYVCSTYRDHVHALSKGVPSKNVMAELFGKETGCSKGRGGSMHIFSAPHNFLGGF 131

Query: 922  SPIATQLPQAVGAAYS-------LKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP 1080
            + IA  +P A GAA+        LK  +       +FGDG T+ G F   LN A + + P
Sbjct: 132  AFIAEGIPVATGAAFQSIYRQQVLKETEDLRVTACFFGDGTTNNGQFFECLNMAVLWKLP 191

Query: 1081 MIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAIT 1260
            +IF   NN WAI            +  + +A+G+  I +DG D LAV  A   A + A  
Sbjct: 192  IIFVVENNQWAIGMAHHRSSSIPEIHKKAEAFGLPGIEVDGMDVLAVRQAAKQAVQRARQ 251

Query: 1261 EGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQE 1440
               P LIEA+TYR   HS +D   + R   E E W  ARDP+ + +K++  N      + 
Sbjct: 252  GDGPTLIEALTYRFRGHSLADPD-ELRSRQEKEAW-VARDPIKKLKKYILDNEIANIGEL 309

Query: 1441 SQLRNNVRQELLQAIQVAERMPKHGLAEL 1527
            ++++N V+ EL QA++ A   P+  ++EL
Sbjct: 310  NEIQNAVKTELEQAVKFAISSPEPNMSEL 338

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>Q10489:ODPA_SCHPO Pyruvate dehydrogenase E1 component alpha subunit, mitochondrial|
            precursor - Schizosaccharomyces pombe (Fission yeast)
          Length = 409

 Score =  132 bits (331), Expect = 6e-30
 Identities = 87/321 (27%), Positives = 147/321 (45%), Gaps = 3/321 (0%)
 Frame = +1

Query: 589  EVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIV 765
            EV+K   L +Y  MVT++ ++       +  +I  F   S G+E             D +
Sbjct: 72   EVTKGELLGLYEKMVTIRRLELACDALYKAKKIRGFCHLSIGQEAVAAGIEGAITLDDSI 131

Query: 766  LPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLP 945
            +  YR  G    RG +++    +L G +    KG+   +H  +   N++  +  +  Q+P
Sbjct: 132  ITSYRCHGFAYTRGLSIRSIIGELMGRQCGASKGKGGSMHIFAK--NFYGGNGIVGAQIP 189

Query: 946  QAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTP 1125
               G  ++ K  +K       +GDG +++G    A N A +   P+IF C NN + + T 
Sbjct: 190  LGAGIGFAQKYLEKPTTTFALYGDGASNQGQAFEAFNMAKLWGLPVIFACENNKYGMGTS 249

Query: 1126 TAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVG 1305
                        RGQ   I  + ++G D LAV  A   A++  +   +P+L+E +TYR G
Sbjct: 250  AERSSAMTEFYKRGQY--IPGLLVNGMDVLAVLQASKFAKKYTVENSQPLLMEFVTYRYG 307

Query: 1306 HHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAI 1485
             HS SD  T YR  +E++  R ARDP+   +K +   G     +   +   +R  + + +
Sbjct: 308  GHSMSDPGTTYRSREEVQKVRAARDPIEGLKKHIMEWGVANANELKNIEKRIRGMVDEEV 367

Query: 1486 QVAERMPKHGLAE--LFTDVY 1542
            ++AE  P     E  LF+DVY
Sbjct: 368  RIAEESPFPDPIEESLFSDVY 388

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>P52902:ODPA_PEA Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial|
            precursor - Pisum sativum (Garden pea)
          Length = 397

 Score =  131 bits (329), Expect = 1e-29
 Identities = 82/279 (29%), Positives = 131/279 (46%)
 Frame = +1

Query: 706  NGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIH 885
            +G+E            +D ++  YR+    L RG TL     +L G +    KG+   +H
Sbjct: 101  DGQEAVAVGMEAGTTKKDCIITAYRDHCTFLGRGGTLLRVYAELMGRRDGCSKGKGGSMH 160

Query: 886  YGSNRLNYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAA 1065
            +      ++     +  Q+P   G A+  K  K ++     +GDG  ++G    ALN +A
Sbjct: 161  FYKKDSGFYGGHGIVGAQVPLGCGLAFGQKYLKDESVTFALYGDGAANQGQLFEALNISA 220

Query: 1066 VAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAR 1245
            + + P I  C NN + + T T    +S     RG    +  +++DG D LAV  A   A+
Sbjct: 221  LWDLPAILVCENNHYGMGTATWRSAKSPAYFKRGDY--VPGLKVDGMDALAVKQACKFAK 278

Query: 1246 EMAITEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWW 1425
            E A+  G PI++E  TYR   HS SD  + YR  DE+   R  RDP+ R RK +  +   
Sbjct: 279  EHALKNG-PIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQERDPIERVRKLLLSHDIA 337

Query: 1426 CGTQESQLRNNVRQELLQAIQVAERMPKHGLAELFTDVY 1542
               +       VR+E+ +AI  A+  P    ++LF++VY
Sbjct: 338  TEKELKDTEKEVRKEVDEAIAKAKDSPMPDPSDLFSNVY 376

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>O13366:ODPA_KLULA Pyruvate dehydrogenase E1 component alpha subunit, mitochondrial|
            precursor - Kluyveromyces lactis (Yeast) (Candida
            sphaerica)
          Length = 412

 Score =  131 bits (329), Expect = 1e-29
 Identities = 88/327 (26%), Positives = 154/327 (47%), Gaps = 9/327 (2%)
 Frame = +1

Query: 589  EVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIV 765
            + +K   L+MY +M+ ++ M+       +  +I  F  +S G+E            +D V
Sbjct: 67   QTTKSNLLQMYKDMIIVRRMEMACDALYKAKKIRGFCHSSVGQEAIAVGIENAITKRDTV 126

Query: 766  LPQYREPGVLLWRGFTLQEFANQLFGNK--LDYGKGRQMPIH----YGSNRLNYFTVSSP 927
            +  YR  G    RG  +Q    +L G +  + +GKG  M ++    YG N +        
Sbjct: 127  ITSYRCHGFTYMRGAAVQAVLAELMGRRTGVSFGKGGSMHLYAPGFYGGNGI-------- 178

Query: 928  IATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNG 1107
            +  Q+P   G A++ +   + AC+   +GDG +++G    + N A +   P +F C NN 
Sbjct: 179  VGAQVPLGAGLAFAHQYKHEDACSFALYGDGASNQGQVFESFNMAKLWNLPAVFCCENNK 238

Query: 1108 WAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEA 1287
            + + T  A          RGQ   I  ++++G D LAVY A   A++  ++   PI++E 
Sbjct: 239  YGMGTAAARSSAMTEYFKRGQY--IPGLKVNGMDILAVYQASKFAKDWTVSGNGPIVLEY 296

Query: 1288 MTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQ 1467
             TYR G HS SD  T YR  DE++H R+  DP++  +  +   G     +        R+
Sbjct: 297  ETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLLELGIATEDEIKAYDKAARK 356

Query: 1468 ELLQAIQVAER--MPKHGLAELFTDVY 1542
             + + +++A+    P+  ++ LF DVY
Sbjct: 357  YVDEQVELADAAPAPEAKMSILFEDVY 383

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>Q9R9N5:ODPA_RHIME Pyruvate dehydrogenase E1 component subunit alpha - Rhizobium|
            meliloti (Sinorhizobium meliloti)
          Length = 348

 Score =  130 bits (327), Expect = 2e-29
 Identities = 89/331 (26%), Positives = 153/331 (46%), Gaps = 1/331 (0%)
 Frame = +1

Query: 550  DDDGGTIYNSRFQEVSKDLALKMYSNMVTLQIMDTIFYEAQRQGRIS-FYLTSNGEEXXX 726
            D  GGTI      E SK+  LK Y  M+ ++  +    +    G I  F     G+E   
Sbjct: 22   DFAGGTI-----AEFSKEDDLKAYREMLLIRRFEEKAGQLYGMGFIGGFCHLYIGQEAVV 76

Query: 727  XXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLN 906
                      D V+  YR+ G +L  G + +    +L G +    KG+   +H  S   +
Sbjct: 77   VGMQLALKEGDQVITGYRDHGHMLACGMSARGVMAELTGRRGGLSKGKGGSMHMFSKEKH 136

Query: 907  YFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMI 1086
            ++     +  Q+    G A++ +       ++ YFGDG  ++G  + + N AA+ + P+I
Sbjct: 137  FYGGHGIVGAQVSLGTGLAFANRYRGNDNVSLAYFGDGAANQGQVYESFNMAALWKLPVI 196

Query: 1087 FFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEG 1266
            +   NN +A+ T  +          RG ++GI   ++DG D  AV +A   A E   +  
Sbjct: 197  YIVENNRYAMGTSVSRASAQTDFSQRGASFGIPGYQVDGMDVRAVKAAADEAVEHCRSGK 256

Query: 1267 RPILIEAMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQ 1446
             PI++E +TYR   HS SD + KYR  DE++  R+  DP+ + +  +   GW    +  Q
Sbjct: 257  GPIILEMLTYRYRGHSMSDPA-KYRSKDEVQKMRSEHDPIEQVKARLTDKGWATEDELKQ 315

Query: 1447 LRNNVRQELLQAIQVAERMPKHGLAELFTDV 1539
            +   VR  +  +   A+  P+  ++EL+TD+
Sbjct: 316  IDKEVRDIVADSADFAQSDPEPDVSELYTDI 346

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>P51267:ODPA_PORPU Pyruvate dehydrogenase E1 component subunit alpha - Porphyra purpurea|
          Length = 344

 Score =  125 bits (315), Expect = 4e-28
 Identities = 88/298 (29%), Positives = 138/298 (46%), Gaps = 7/298 (2%)
 Frame = +1

Query: 655  IFYEAQRQGRISFYLTSNGEEXXXXXXXXXXXXQDIVLPQYREPGVLLWRGFTLQEFANQ 834
            ++Y+ +  G +  Y   NG+E            +D V   YR+    L +G   Q    +
Sbjct: 44   MYYKGKMFGFVHLY---NGQEAVSTGVIKLLDSKDYVCSTYRDHVHALSKGVPSQNVMAE 100

Query: 835  LFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAYS-------LKMDKKKA 993
            LFG +    +GR   +H  S   N+    + IA  +P A GAA+        LK   +  
Sbjct: 101  LFGKETGCSRGRGGSMHIFSAPHNFLGGFAFIAEGIPVATGAAFQSIYRQQVLKEPGELR 160

Query: 994  CAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQA 1173
                +FGDG T+ G F   LN A + + P+IF   NN WAI            +  + +A
Sbjct: 161  VTACFFGDGTTNNGQFFECLNMAVLWKLPIIFVVENNQWAIGMAHHRSSSIPEIHKKAEA 220

Query: 1174 YGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDDSTKYRPADE 1353
            +G+  I +DG D LAV      A E A     P LIEA+TYR   HS +D   + R   E
Sbjct: 221  FGLPGIEVDGMDVLAVRQVAEKAVERARQGQGPTLIEALTYRFRGHSLADPD-ELRSRQE 279

Query: 1354 MEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAEL 1527
             E W  ARDP+ + +K +  N      + + ++++V+ +L Q+++ A   P+  ++EL
Sbjct: 280  KEAW-VARDPIKKLKKHILDNQIASSDELNDIQSSVKIDLEQSVEFAMSSPEPNISEL 336

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>P52899:ODPA_CAEEL Probable pyruvate dehydrogenase E1 component alpha subunit,|
            mitochondrial precursor - Caenorhabditis elegans
          Length = 397

 Score =  125 bits (314), Expect = 6e-28
 Identities = 91/349 (26%), Positives = 161/349 (46%), Gaps = 3/349 (0%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            ++++ ALK Y +M  ++ M++      ++ +I  F    +G+E             D V+
Sbjct: 50   LNREDALKYYRDMQVIRRMESAAGNLYKEKKIRGFCHLYSGQEACAVGMKAAMTEGDAVI 109

Query: 769  PQYREPGVLLWRGFTLQEFANQLFGNKLD--YGKGRQMPIHYGSNRLNYFTVSSPIATQL 942
              YR  G     G T+ E   +L G      +GKG  M ++      N++  +  +  Q 
Sbjct: 110  TAYRCHGWTWLLGATVTEVLAELTGRVAGNVHGKGGSMHMY----TKNFYGGNGIVGAQQ 165

Query: 943  PQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAIST 1122
            P   G A ++K  ++K   +T +GDG  ++G    A N A + + P++F C NNG+ + T
Sbjct: 166  PLGAGVALAMKYREQKNVCVTLYGDGAANQGQLFEATNMAKLWDLPVLFVCENNGFGMGT 225

Query: 1123 PTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRV 1302
                   S    TRG    +  I +DG D LAV  A   A+E   +   P+++E  TYR 
Sbjct: 226  TAERSSASTEYYTRGDY--VPGIWVDGMDILAVREATKWAKEYCDSGKGPLMMEMATYRY 283

Query: 1303 GHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQA 1482
              HS SD  T YR  +E++  R  RDP++ ++  +  +      +   +   VR+E+ +A
Sbjct: 284  HGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDRIITSSLATEEELKAIDKEVRKEVDEA 343

Query: 1483 IQVAERMPKHGLAELFTDVYDQIPSNLRQQERSLLDTIKRHPAEYPADV 1629
            +++A          L+ D+Y   P+  ++   + +D     P +  ADV
Sbjct: 344  LKIATSDGVLPPEALYADIYHNTPA--QEIRGATIDETIVQPFKTSADV 390

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>P52900:ODPA_SMIMA Pyruvate dehydrogenase E1 component alpha subunit, mitochondrial|
            precursor - Sminthopsis macroura (Stripe-faced dunnart)
          Length = 363

 Score =  123 bits (308), Expect = 3e-27
 Identities = 89/322 (27%), Positives = 143/322 (44%), Gaps = 1/322 (0%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            ++++  LK Y  M T++ M+    +  +Q  I  F    +G+E             D V+
Sbjct: 29   LTREEGLKYYKIMQTVRRMELKADQLYKQKIIRGFCHLYDGQEACCMGLEAGINPTDHVI 88

Query: 769  PQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQ 948
              YR  G    RG  ++E   +L G +    KG+   +H  +   N++  +  +  Q+P 
Sbjct: 89   TAYRAHGFTYTRGLPVREILAELTGRRGGCAKGKGGSMHMYAK--NFYGGNGIVGAQVPL 146

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
             VG A + K ++K    +T +GDG  ++G    A N AA+ + P IF C NN + + T  
Sbjct: 147  GVGIALACKYNEKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSV 206

Query: 1129 AEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGH 1308
                 S     RG    I  I +DG D L V  A   A     +   P+L+E  TYR   
Sbjct: 207  ERAAASTDYYKRGDF--IPGIMVDGMDVLCVREATKFAAAYCRSGKGPMLMELQTYRYHG 264

Query: 1309 HSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQ 1488
            HS SD    YR  +E++  R+  DP+   +  +  N      +  ++   VR+E+  A Q
Sbjct: 265  HSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNNNLASIEELKEIDVEVRKEIEDAAQ 324

Query: 1489 VAERMPKHGLAELFTDVYDQIP 1554
             A   P+  L EL   +Y + P
Sbjct: 325  FATADPEPPLEELGYHIYSRDP 346

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>Q5R490:ODPA_PONPY Pyruvate dehydrogenase E1 component alpha subunit, somatic form,|
            mitochondrial precursor - Pongo pygmaeus (Orangutan)
          Length = 390

 Score =  122 bits (307), Expect = 4e-27
 Identities = 88/322 (27%), Positives = 142/322 (44%), Gaps = 1/322 (0%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            ++++  LK Y  M T++ M+    +  +Q  I  F    +G+E             D ++
Sbjct: 56   LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLI 115

Query: 769  PQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQ 948
              YR  G    RG +++E   +L G K    KG+   +H  +   N++  +  +  Q+P 
Sbjct: 116  TAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAK--NFYGGNGIVGAQVPL 173

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
              G A + K + K    +T +GDG  ++G    A N AA+ + P IF C NN + + T  
Sbjct: 174  GAGIALACKYNGKDEVCLTLYGDGAANQGQIFGAYNMAALWKLPCIFICENNRYGMGTSV 233

Query: 1129 AEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGH 1308
                 S     RG    I  +R+DG D L V  A   A     +   PIL+E  TYR   
Sbjct: 234  ERAAASTDYYKRGDF--IPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHG 291

Query: 1309 HSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQ 1488
            HS SD    YR  +E++  R+  DP+   +  +  +      +  ++   VR+E+  A Q
Sbjct: 292  HSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQ 351

Query: 1489 VAERMPKHGLAELFTDVYDQIP 1554
             A   P+  L EL   +Y   P
Sbjct: 352  FATADPEPPLEELGYHIYSSDP 373

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>P08559:ODPA_HUMAN Pyruvate dehydrogenase E1 component alpha subunit, somatic form,|
            mitochondrial precursor - Homo sapiens (Human)
          Length = 390

 Score =  122 bits (306), Expect = 5e-27
 Identities = 88/322 (27%), Positives = 142/322 (44%), Gaps = 1/322 (0%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            ++++  LK Y  M T++ M+    +  +Q  I  F    +G+E             D ++
Sbjct: 56   LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLI 115

Query: 769  PQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQ 948
              YR  G    RG +++E   +L G K    KG+   +H  +   N++  +  +  Q+P 
Sbjct: 116  TAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAK--NFYGGNGIVGAQVPL 173

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
              G A + K + K    +T +GDG  ++G    A N AA+ + P IF C NN + + T  
Sbjct: 174  GAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSV 233

Query: 1129 AEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGH 1308
                 S     RG    I  +R+DG D L V  A   A     +   PIL+E  TYR   
Sbjct: 234  ERAAASTDYYKRGDF--IPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHG 291

Query: 1309 HSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQ 1488
            HS SD    YR  +E++  R+  DP+   +  +  +      +  ++   VR+E+  A Q
Sbjct: 292  HSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQ 351

Query: 1489 VAERMPKHGLAELFTDVYDQIP 1554
             A   P+  L EL   +Y   P
Sbjct: 352  FATADPEPPLEELGYHIYSSDP 373

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>P29804:ODPA_PIG Pyruvate dehydrogenase E1 component alpha subunit, somatic form,|
            mitochondrial precursor - Sus scrofa (Pig)
          Length = 389

 Score =  122 bits (305), Expect = 6e-27
 Identities = 87/322 (27%), Positives = 143/322 (44%), Gaps = 1/322 (0%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            ++++  LK Y  M T++ M+    +  +Q  I  F    +G+E             D ++
Sbjct: 55   LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLI 114

Query: 769  PQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQ 948
              YR  G    RG +++E   +L G +   GKG+   +H  +   N++  +  +  Q+P 
Sbjct: 115  TAYRAHGFTFTRGLSVREILAELTGRRGGCGKGKGGSMHMYAK--NFYGGNGIVGAQVPL 172

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
              G A + K + K    +T +GDG  ++G    A N AA+ + P +F C NN + + T  
Sbjct: 173  GAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCVFICENNRYGMGTSV 232

Query: 1129 AEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGH 1308
                 S     RG    I  +R+DG D L V  A   A     +   PIL+E  TYR   
Sbjct: 233  ERAAASTDYYKRGDF--IPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHG 290

Query: 1309 HSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQ 1488
            HS SD    YR  +E++  R+  DP+   +  +  +      +  ++   VR+E+  A Q
Sbjct: 291  HSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQ 350

Query: 1489 VAERMPKHGLAELFTDVYDQIP 1554
             A   P+  L EL   +Y   P
Sbjct: 351  FATADPEPPLEELGYHIYCNDP 372

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>Q8HXW9:ODPA_MACFA Pyruvate dehydrogenase E1 component alpha subunit, somatic form,|
            mitochondrial precursor - Macaca fascicularis (Crab
            eating macaque) (Cynomolgus monkey)
          Length = 390

 Score =  121 bits (304), Expect = 8e-27
 Identities = 88/322 (27%), Positives = 140/322 (43%), Gaps = 1/322 (0%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            ++++  LK Y  M T++ M+    +  +Q  I  F    +G+E             D ++
Sbjct: 56   LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLI 115

Query: 769  PQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQ 948
              YR  G    RG +++E   +L G K    KG+    H  +   N++  +  +  Q+P 
Sbjct: 116  TAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSTHMYAK--NFYRGNGIVGAQVPL 173

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
              G A + K + K    +T +GDG   +G    A N AA+ + P IF C NN + + T  
Sbjct: 174  GAGIALACKYNGKDEVCLTLYGDGAADQGQIFEAYNMAALWKLPCIFICENNRYGMGTSV 233

Query: 1129 AEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGH 1308
                 S     RG    I  +R+DG D L V  A   A     +   PIL+E  TYR   
Sbjct: 234  ERAAASTDYYKRGDF--IPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHG 291

Query: 1309 HSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQ 1488
            HS SD    YR  +E++  R+  DP+   +  +  +      +  ++   VR+E+  A Q
Sbjct: 292  HSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQ 351

Query: 1489 VAERMPKHGLAELFTDVYDQIP 1554
             A   P+  L EL   +Y   P
Sbjct: 352  FATADPEPPLEELGYHIYSSDP 373

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>O66112:ODPA_ZYMMO Pyruvate dehydrogenase E1 component subunit alpha - Zymomonas mobilis|
          Length = 354

 Score =  120 bits (301), Expect = 2e-26
 Identities = 77/265 (29%), Positives = 127/265 (47%), Gaps = 3/265 (1%)
 Frame = +1

Query: 754  QDIVLPQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIA 933
            +D V+  YRE G +L  G   +    +L G       G+   +H  S    +F  +  + 
Sbjct: 90   RDSVITGYREHGHMLAYGIDPKIVMAELTGRASGISHGKGGSMHMFSTEHKFFGGNGIVG 149

Query: 934  TQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWA 1113
             Q+P   G A++ K      C+  YFGDG  ++G  + A N AA+ + P+IF   NNG+A
Sbjct: 150  AQVPLGAGLAFAHKYRNDGGCSAAYFGDGSANQGQVYEAYNMAALWKLPVIFVIENNGYA 209

Query: 1114 ISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMT 1293
            + T          +  RG  +GI ++ +DG D L V  A   A +       PI++E  T
Sbjct: 210  MGTSIQRANAHTALSERGAGFGIPALVVDGMDVLEVRGAATVAVDWVQAGKGPIILEMKT 269

Query: 1294 YRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQ---LRNNVR 1464
            YR   HS SD + +YR  +E+   +   DP+   +K    + +  G  E++   L  ++R
Sbjct: 270  YRYRGHSMSDPA-RYRSREEVNDMKENHDPLDNLKK----DLFAAGVPEAELVKLDEDIR 324

Query: 1465 QELLQAIQVAERMPKHGLAELFTDV 1539
            Q++ +A   AE+ P     EL+T++
Sbjct: 325  QQVKEAADFAEKAPLPADEELYTNI 349

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>Q06437:ODPAT_RAT Pyruvate dehydrogenase E1 component alpha subunit, testis-specific|
            form, mitochondrial precursor - Rattus norvegicus (Rat)
          Length = 391

 Score =  120 bits (301), Expect = 2e-26
 Identities = 83/322 (25%), Positives = 149/322 (46%), Gaps = 1/322 (0%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            ++++ ALK Y NM  ++ M+    +  +Q  I  F    +G+E             D ++
Sbjct: 57   LTREEALKYYRNMQVIRRMELKADQLYKQKFIRGFCHLCDGQEACNVGLEAGINPTDHII 116

Query: 769  PQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQ 948
              YR  G+   RG +++    +L G K    KG+   +H  +   N++  +  +  Q+P 
Sbjct: 117  TSYRAHGLCYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYAK--NFYGGNGIVGAQVPL 174

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
              G A + K  K     +  +GDG  ++G    A N +A+ + P +F C NN + + T  
Sbjct: 175  GAGVALACKYLKNGQICLALYGDGAANQGQVFEAYNMSALWKLPCVFICENNRYGMGTAI 234

Query: 1129 AEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGH 1308
                 S     +G  + I  +R++G D L+V  A   A +   +   PI++E  TYR   
Sbjct: 235  ERSAASTDYHKKG--FVIPGLRVNGMDILSVREATKFAADHCRSGKGPIVMELQTYRYHG 292

Query: 1309 HSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQ 1488
            HS SD    YR  +E+++ R+  DP+   R+ +  N      +  ++  +V++E+ +A Q
Sbjct: 293  HSMSDPGISYRTREEVQNVRSKSDPIMLLRERMISNNLSSVEELKEIDADVKKEVEEAAQ 352

Query: 1489 VAERMPKHGLAELFTDVYDQIP 1554
             A   P+  L +L   +Y Q P
Sbjct: 353  FATTDPEPPLEDLANYLYHQNP 374

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>Q1RJX4:ODPA_RICBR Pyruvate dehydrogenase E1 component subunit alpha - Rickettsia bellii|
            (strain RML369-C)
          Length = 326

 Score =  119 bits (298), Expect = 4e-26
 Identities = 75/316 (23%), Positives = 145/316 (45%), Gaps = 1/316 (0%)
 Frame = +1

Query: 598  KDLALKMYSNMVTLQIMDTIFYEAQRQGRIS-FYLTSNGEEXXXXXXXXXXXXQDIVLPQ 774
            K+  +K + +M+ L+  +    +    G I  F     G+E            +D ++  
Sbjct: 12   KEEYIKSFKDMLLLRRFEEKCGQLYGMGEIGGFCHLYIGQEAVISAVDMVKQKEDSMVTS 71

Query: 775  YREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAV 954
            YR+   ++  G   +    +L G      KG+   +H       ++     +  Q+P   
Sbjct: 72   YRDHAHIILAGTEPKYVLAELMGRATGCSKGKGGSMHLFDVPNKFYGGHGIVGAQVPIGT 131

Query: 955  GAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAE 1134
            G A++ K +       T+ GDG  ++G  + A N AA+   P+++   NN +++ T  A 
Sbjct: 132  GLAFAEKYNGTNNICFTFLGDGAVNQGQVYEAFNMAALWGLPVVYIIENNEYSMGTSVAR 191

Query: 1135 QFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHS 1314
                  +  +G+++GI+  +L+G D   +Y  V  A E       P+++E  TYR   HS
Sbjct: 192  STFMRDLYKKGESFGIKGFQLNGMDFEEMYDGVKQAAEYVRENSMPLILEVKTYRYRGHS 251

Query: 1315 TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVA 1494
             SD + KYR  +E+E ++  RDP++  RK +  N +       ++  +V++ + +A++ +
Sbjct: 252  MSDPA-KYRSKEEVETYK-ERDPITEIRKIILENNYASEADLKEIEQSVKEIVKEAVEFS 309

Query: 1495 ERMPKHGLAELFTDVY 1542
            E  P     EL+T +Y
Sbjct: 310  ENSPLPNEEELYTQIY 325

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>P35486:ODPA_MOUSE Pyruvate dehydrogenase E1 component alpha subunit, somatic form,|
            mitochondrial precursor - Mus musculus (Mouse)
          Length = 390

 Score =  117 bits (294), Expect = 1e-25
 Identities = 86/322 (26%), Positives = 140/322 (43%), Gaps = 1/322 (0%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            ++++  LK Y  M T++ M+    +  +Q  I  F    +G+E             D ++
Sbjct: 56   LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLI 115

Query: 769  PQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQ 948
              YR  G    RG  ++    +L G +    KG+   +H  +   N++  +  +  Q+P 
Sbjct: 116  TAYRAHGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAK--NFYGGNGIVGAQVPL 173

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
              G A + K + K    +T +GDG  ++G    A N AA+ + P IF C NN + + T  
Sbjct: 174  GAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSV 233

Query: 1129 AEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGH 1308
                 S     RG    I  +R+DG D L V  A   A     +   PIL+E  TYR   
Sbjct: 234  ERAAASTDYYKRGDF--IPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHG 291

Query: 1309 HSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQ 1488
            HS SD    YR  +E++  R+  DP+   +  +  +      +  ++   VR+E+  A Q
Sbjct: 292  HSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQ 351

Query: 1489 VAERMPKHGLAELFTDVYDQIP 1554
             A   P+  L EL   +Y   P
Sbjct: 352  FATADPEPPLEELGYHIYSSDP 373

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>P29803:ODPAT_HUMAN Pyruvate dehydrogenase E1 component alpha subunit, testis-specific|
            form, mitochondrial precursor - Homo sapiens (Human)
          Length = 388

 Score =  117 bits (293), Expect = 2e-25
 Identities = 86/312 (27%), Positives = 137/312 (43%), Gaps = 1/312 (0%)
 Frame = +1

Query: 610  LKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVLPQYREP 786
            LK Y  M+T++ M+    +  +Q  I  F    +G+E             D V+  YR  
Sbjct: 60   LKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAH 119

Query: 787  GVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAVGAAY 966
            GV   RG +++    +L G +    KG+   +H  +   N++  +  +  Q P   G A 
Sbjct: 120  GVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPLGAGIAL 177

Query: 967  SLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRS 1146
            + K        +T +GDG  ++G    A N AA+ + P +F C NN + + T T     S
Sbjct: 178  ACKYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTSTERAAAS 237

Query: 1147 DGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDD 1326
                 RG    I  +++DG D L V  A   A     +   PIL+E  TYR   HS SD 
Sbjct: 238  PDYYKRGNF--IPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSDP 295

Query: 1327 STKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAERMP 1506
               YR  +E++  R+ RDP+   +  +  +      +  ++   VR+E+  A Q A   P
Sbjct: 296  GVSYRTREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQFATTDP 355

Query: 1507 KHGLAELFTDVY 1542
            +  L EL   +Y
Sbjct: 356  EPHLEELGHHIY 367

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>P26284:ODPA_RAT Pyruvate dehydrogenase E1 component alpha subunit, somatic form,|
            mitochondrial precursor - Rattus norvegicus (Rat)
          Length = 390

 Score =  117 bits (292), Expect = 2e-25
 Identities = 86/322 (26%), Positives = 140/322 (43%), Gaps = 1/322 (0%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            ++++  LK Y  M T++ M+    +  +Q  I  F    +G+E             D ++
Sbjct: 56   LTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLI 115

Query: 769  PQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQ 948
              YR  G    RG  ++    +L G +    KG+   +H  +   N++  +  +  Q+P 
Sbjct: 116  TAYRAHGFTFNRGHAVRAILAELTGRRGGCAKGKGGSMHMYAK--NFYGGNGIVGAQVPL 173

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
              G A + K + K    +T +GDG  ++G    A N AA+ + P IF C NN + + T  
Sbjct: 174  GAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSV 233

Query: 1129 AEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGH 1308
                 S     RG    I  +R+DG D L V  A   A     +   PIL+E  TYR   
Sbjct: 234  ERAAASTDYYKRGDF--IPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHG 291

Query: 1309 HSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQ 1488
            HS SD    YR  +E++  R+  DP+   +  +  +      +  ++   VR+E+  A Q
Sbjct: 292  HSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQ 351

Query: 1489 VAERMPKHGLAELFTDVYDQIP 1554
             A   P+  L EL   +Y   P
Sbjct: 352  FATADPEPPLEELGYHIYSSDP 373

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>Q4UKQ6:ODPA_RICFE Pyruvate dehydrogenase E1 component subunit alpha - Rickettsia felis|
            (Rickettsia azadi)
          Length = 326

 Score =  116 bits (291), Expect = 3e-25
 Identities = 76/317 (23%), Positives = 144/317 (45%), Gaps = 1/317 (0%)
 Frame = +1

Query: 595  SKDLALKMYSNMVTLQIMDTIFYEAQRQGRIS-FYLTSNGEEXXXXXXXXXXXXQDIVLP 771
            +K+  +K + +M+ L+  +    +    G I  F     G+E             D  + 
Sbjct: 11   TKEEYIKSFKDMLLLRRFEEKCGQLYGMGEIGGFCHLYIGQEAVISAVDTVKQKGDSTIT 70

Query: 772  QYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQA 951
             YR+   ++  G   +    +L G      KG+   +H       ++     +  Q+P  
Sbjct: 71   SYRDHAHIILAGTEPKYVLAELMGRATGCSKGKGGSMHLFDIPNKFYGGHGIVGAQVPIG 130

Query: 952  VGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTA 1131
             G A++ K +       T+ GDG  ++G  + A N AA+   P+++   NN +++ T  A
Sbjct: 131  TGLAFAEKYNGTNNICFTFLGDGAVNQGQVYEAFNMAALWGLPVVYIIENNEYSMGTSVA 190

Query: 1132 EQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHH 1311
                   +  +G+++GI+  +LDG D   +Y+    A E       P+++E  TYR   H
Sbjct: 191  RSTFMRDLYKKGESFGIKGFQLDGMDFEEMYNGAKQAAEYVRENSFPLILEVKTYRYRGH 250

Query: 1312 STSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQV 1491
            S SD + KYR  +E+E ++  RDP+   RK +  N +       ++  +V++ + +A++ 
Sbjct: 251  SMSDPA-KYRSKEEVEQYK-ERDPLVIIRKTILDNKYATEADLKEIEQSVKEIVKEAVKF 308

Query: 1492 AERMPKHGLAELFTDVY 1542
            +E  P     EL+T+VY
Sbjct: 309  SENSPLPDEGELYTEVY 325

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>P35487:ODPAT_MOUSE Pyruvate dehydrogenase E1 component alpha subunit, testis-specific|
            form, mitochondrial precursor - Mus musculus (Mouse)
          Length = 391

 Score =  115 bits (287), Expect = 8e-25
 Identities = 83/318 (26%), Positives = 142/318 (44%), Gaps = 2/318 (0%)
 Frame = +1

Query: 607  ALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVLPQYRE 783
            ALK Y  M  ++ M+    +  +Q  I  F    +G+E             D V+  YR 
Sbjct: 62   ALKYYRTMQVIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYRA 121

Query: 784  PGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIH-YGSNRLNYFTVSSPIATQLPQAVGA 960
             G    RG +++    +L G K    KG+   +H YG N   ++  +  +  Q+P   G 
Sbjct: 122  HGFCYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYGKN---FYGGNGIVGAQVPLGAGV 178

Query: 961  AYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQF 1140
            A++ K  K     +  +GDG  ++G    A N +A+ + P +F C NN + + T      
Sbjct: 179  AFACKYLKNGQVCLALYGDGAANQGQVFEAYNMSALWKLPCVFICENNLYGMGTSNERSA 238

Query: 1141 RSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTS 1320
             S     +G  + I  +R++G D L V  A   A +   +   PI++E  TYR   HS S
Sbjct: 239  ASTDYHKKG--FIIPGLRVNGMDILCVREATKFAADHCRSGKGPIVMELQTYRYHGHSMS 296

Query: 1321 DDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVAER 1500
            D    YR  +E+ + R+  DP+   R+ +  N      +  ++  +V++E+  A Q A  
Sbjct: 297  DPGISYRSREEVHNVRSKSDPIMLLRERIISNNLSNIEELKEIDADVKKEVEDAAQFATT 356

Query: 1501 MPKHGLAELFTDVYDQIP 1554
             P+  + ++   +Y Q P
Sbjct: 357  DPEPAVEDIANYLYHQDP 374

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>Q92IS3:ODPA_RICCN Pyruvate dehydrogenase E1 component subunit alpha - Rickettsia|
            conorii
          Length = 326

 Score =  112 bits (279), Expect = 7e-24
 Identities = 76/317 (23%), Positives = 140/317 (44%), Gaps = 1/317 (0%)
 Frame = +1

Query: 595  SKDLALKMYSNMVTLQIMDTIFYEAQRQGRIS-FYLTSNGEEXXXXXXXXXXXXQDIVLP 771
            +K+  +K + +M+ L+  +    +    G I  F     G+E             D  + 
Sbjct: 11   TKEEYIKSFKDMLLLRRFEEKCGQLYGMGEIGGFCHLYIGQEAVISAIDMVKQKGDSTIT 70

Query: 772  QYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQA 951
             YR+   ++  G   +    +L G      KG+   +H  +    ++     +  Q+P  
Sbjct: 71   SYRDHAHIILAGTEPKYVLAELMGRATGCSKGKGGSMHLFNVPNKFYGGHGIVGAQVPIG 130

Query: 952  VGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTA 1131
             G A+  K +       T+ GDG  ++G  + A N AA+   P+++   NN +++ T  A
Sbjct: 131  TGLAFVEKYNDTHNICFTFLGDGAVNQGQVYEAFNMAALWGLPVVYIIENNEYSMGTSVA 190

Query: 1132 EQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHH 1311
                   +  +G ++GI+  +LDG D   +Y     A E       P+++E  TYR   H
Sbjct: 191  RSTFMRDLYKKGASFGIKGFQLDGMDFEEMYDGSKQAAEYVRENSFPLILEVKTYRYRGH 250

Query: 1312 STSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQV 1491
            S SD + KYR  +E+E ++  RDP+   RK +  N +        +  +V++ + +A++ 
Sbjct: 251  SMSDPA-KYRSKEEVEQYK-ERDPLVIIRKTILDNKYVTEADLKAIEQSVKEIVKEAVEF 308

Query: 1492 AERMPKHGLAELFTDVY 1542
            +E  P     EL+T VY
Sbjct: 309  SENSPLPDEGELYTQVY 325

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>Q9ZDR4:ODPA_RICPR Pyruvate dehydrogenase E1 component subunit alpha - Rickettsia|
            prowazekii
          Length = 326

 Score =  111 bits (278), Expect = 9e-24
 Identities = 74/316 (23%), Positives = 141/316 (44%), Gaps = 1/316 (0%)
 Frame = +1

Query: 598  KDLALKMYSNMVTLQIMDTIFYEAQRQGRIS-FYLTSNGEEXXXXXXXXXXXXQDIVLPQ 774
            K+  +K + +M+ L+  +    +    G+I  F     G+E             D  +  
Sbjct: 12   KEEYIKSFKDMLLLRRFEEKCGQLYGMGKIGGFCHLYIGQEAVISAVAMIKKKGDSTITS 71

Query: 775  YREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAV 954
            YR+   ++  G   +    +L G      KG+   +H       ++     +  Q+P   
Sbjct: 72   YRDHAHIILAGTEPKYVLAELMGRATGCSKGKGGSMHLFDIPNKFYGGHGIVGAQVPIGT 131

Query: 955  GAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAE 1134
            G A++ K +       T+ GDG  ++G  + A N A++   P+++   NN +++ T  A 
Sbjct: 132  GLAFAEKYNGTNNICFTFLGDGAVNQGQVYEAFNMASLWGLPIVYIIENNEYSMGTSVAR 191

Query: 1135 QFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHS 1314
                  +  +G+++GIR  +LDG D   +Y+      E       P+++E  TYR   HS
Sbjct: 192  STFMCDLYKKGESFGIRGFQLDGMDFEEMYNGTKQVAEYVRENSFPVILEVKTYRYRGHS 251

Query: 1315 TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVA 1494
             SD + KYR  +E+E ++  RD + R R+ +  N +        +  +VR+ +  A++ +
Sbjct: 252  MSDPA-KYRSKEEVEKYK-ERDTLVRIREIILDNKYATEADLKAIEQSVREIIKVAVEFS 309

Query: 1495 ERMPKHGLAELFTDVY 1542
            E  P     EL+T++Y
Sbjct: 310  ENSPLPAEDELYTEIY 325

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>Q68XA9:ODPA_RICTY Pyruvate dehydrogenase E1 component subunit alpha - Rickettsia typhi|
          Length = 326

 Score =  107 bits (268), Expect = 1e-22
 Identities = 72/316 (22%), Positives = 139/316 (43%), Gaps = 1/316 (0%)
 Frame = +1

Query: 598  KDLALKMYSNMVTLQIMDTIFYEAQRQGRIS-FYLTSNGEEXXXXXXXXXXXXQDIVLPQ 774
            K+  +K + +M+ L+  +    +    G I  F     G+E             D  +  
Sbjct: 12   KEEYIKSFKDMLLLRRFEEKCGQLYGMGEIGGFCHLYIGQEAVISAVELIKKKGDSTITS 71

Query: 775  YREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQAV 954
            YR+   ++  G   +    +L G      KG+   +H       ++     +  Q+P   
Sbjct: 72   YRDHAHIILAGTEPKYVLAELMGRATGCSKGKGGSMHLFDIPNKFYGGHGIVGAQVPIGT 131

Query: 955  GAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAE 1134
            G A++ K +       T+ GDG  ++G  + A N A++   P+++   NN +++ T  + 
Sbjct: 132  GLAFAEKYNGTNNICFTFLGDGAVNQGQVYEAFNMASLWGLPVVYIIENNEYSMGTSVSR 191

Query: 1135 QFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHS 1314
                  +  +G+++GIR  +LDG D   +Y+      E       P+++E  TYR   HS
Sbjct: 192  STFMRDLYKKGESFGIRGFQLDGMDFEEMYNGTKQVAEYVRENSFPVILEVKTYRYRGHS 251

Query: 1315 TSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQVA 1494
             SD + KYR  +E+  ++  RD + R R+ +  N +        +  +V++ +  A++ +
Sbjct: 252  MSDPA-KYRSKEEVAKYK-ERDTLVRIRQIILDNKYATEEDLKAIERSVQEVIKVAVEFS 309

Query: 1495 ERMPKHGLAELFTDVY 1542
            E  P     EL+TD+Y
Sbjct: 310  ENSPLPSEDELYTDIY 325

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>P27745:ACOA_RALEH Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha -|
            Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 /
            Stanier 337) (Cupriavidus necator (strain ATCC 17699 /
            H16 / DSM 428 / Stanier 337))
          Length = 333

 Score =  105 bits (263), Expect = 5e-22
 Identities = 85/318 (26%), Positives = 130/318 (40%), Gaps = 1/318 (0%)
 Frame = +1

Query: 592  VSKDLALKMYSNMVTLQIMDTIFYEAQRQGRI-SFYLTSNGEEXXXXXXXXXXXXQDIVL 768
            + K+  L +Y  M T++  +   +    +G I  F     GEE             D + 
Sbjct: 14   LDKETLLTVYRKMRTIRDFEERLHVDFGRGDIPGFVHLYAGEEAAGVGILHHLNDGDRIA 73

Query: 769  PQYREPGVLLWRGFTLQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPIATQLPQ 948
              +R  G  + +G        +++G K     G+   +H           +  +    P 
Sbjct: 74   STHRGHGHCIAKGVDPVAMMKEIYGKKGGSCNGKGGSMHIADLSKGMMGANGILGAGAPL 133

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
              GAA + K   K    IT+ GDG +++G F  +LN AAV   P+IF   NNG+A ST  
Sbjct: 134  ICGAALAAKFRGKGEVGITFCGDGASNQGTFLESLNLAAVWNLPVIFVIENNGYAESTSR 193

Query: 1129 AEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGH 1308
                  D  V R   +GI  + +DG D  AV+ A       A   G P L+E    R   
Sbjct: 194  DYGTAVDSYVDRAAGFGIPGVTVDGTDFFAVHEAAGEVIRRAREGGGPSLLECKMVRFYG 253

Query: 1309 HSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQGNGWWCGTQESQLRNNVRQELLQAIQ 1488
            H   D  T YR A E++  R  +D +  + + V   G     +   +   V   +  A+Q
Sbjct: 254  HFEGDAQT-YRAAGELDDIRANKDCLKLFGRAVTQAGVVAREELDTIDREVAALIEHAVQ 312

Query: 1489 VAERMPKHGLAELFTDVY 1542
             A+  P+ G  +L TDVY
Sbjct: 313  EAKAAPQPGPEDLLTDVY 330

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>Q9ZM94:DXS_HELPJ 1-deoxy-D-xylulose-5-phosphate synthase - Helicobacter pylori J99|
            (Campylobacter pylori J99)
          Length = 618

 Score = 42.4 bits (98), Expect = 0.006
 Identities = 26/91 (28%), Positives = 43/91 (47%)
 Frame = +1

Query: 904  NYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPM 1083
            +YF ++   +T +   VG A + ++ +     I   GDG  S G F+ ALN     + PM
Sbjct: 106  DYF-IAGHSSTSVSIGVGVAKAFRLKQTLGMPIALLGDGSISAGIFYEALNELGDRKYPM 164

Query: 1084 IFFCRNNGWAISTPTAEQFRSDGVVTRGQAY 1176
            I    +N  +ISTP     ++   + +G  Y
Sbjct: 165  IMILNDNEMSISTPIGALSKALSQLMKGPFY 195

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>Q92RJ1:DXS_RHIME 1-deoxy-D-xylulose-5-phosphate synthase - Rhizobium meliloti|
            (Sinorhizobium meliloti)
          Length = 645

 Score = 41.6 bits (96), Expect = 0.011
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A + ++D K    I   GDG  S G    ALN A   +A +I    +N  
Sbjct: 128  STSISAGLGMAVAAELDGKSRNVIAVIGDGAMSAGMAFEALNNAGALDARLIVILNDNDM 187

Query: 1111 AISTPTAEQFRSDGVVTRGQAY-GIRSI 1191
            +I+ PT         +  G+ Y GIR +
Sbjct: 188  SIAPPTGAMSAYLARLASGRTYMGIREV 215

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>Q21UG7:DXS_RHOFD 1-deoxy-D-xylulose-5-phosphate synthase - Rhodoferax ferrireducens|
            (strain DSM 15236 / ATCC BAA-621 / T118)
          Length = 632

 Score = 41.2 bits (95), Expect = 0.014
 Identities = 25/82 (30%), Positives = 39/82 (47%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + K+  ++  AI   GDG  + G    ALN A VA+  ++    +N  
Sbjct: 122  STSISAALGMALAAKIRGEERYAIAVIGDGALTAGMAFEALNNAGVADCNLLVILNDNDM 181

Query: 1111 AISTPTAEQFRSDGVVTRGQAY 1176
            +IS P     R    +  GQ Y
Sbjct: 182  SISPPVGALNRHLAKLMSGQFY 203

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>Q1MKN4:DXS_RHIL3 1-deoxy-D-xylulose-5-phosphate synthase - Rhizobium leguminosarum bv.|
            viciae (strain 3841)
          Length = 638

 Score = 40.4 bits (93), Expect = 0.024
 Identities = 36/132 (27%), Positives = 53/132 (40%), Gaps = 7/132 (5%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A +  +DK     I   GDG  S G  + ALN A   +A +I    +N  
Sbjct: 123  STSISAGLGMAIAADLDKSDRRVIAVIGDGAMSAGMAYEALNNAGALDARLIVILNDNDM 182

Query: 1111 AISTPTAEQFRSDGVVTRGQAY-GIR------SIRLDGNDTLAVYSAVHTAREMAITEGR 1269
            +I+ PT         +  G+ Y G R      +  L  N   A+  AV  AR      G 
Sbjct: 183  SIAPPTGAMSAYLARLASGRTYMGFRDFGKKLTAYLGKNIDRAITRAVEHAR--GYVTGG 240

Query: 1270 PILIEAMTYRVG 1305
             +  E   Y +G
Sbjct: 241  TMFEEMGFYHIG 252

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>O25121:DXS_HELPY 1-deoxy-D-xylulose-5-phosphate synthase - Helicobacter pylori|
            (Campylobacter pylori)
          Length = 618

 Score = 40.4 bits (93), Expect = 0.024
 Identities = 26/91 (28%), Positives = 42/91 (46%)
 Frame = +1

Query: 904  NYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPM 1083
            +YF ++   +T +   VG A +  + +     I   GDG  S G F+ ALN     + PM
Sbjct: 106  DYF-IAGHSSTSVSIGVGVAKAFCLKQALGMPIALLGDGSISAGIFYEALNELGDRKYPM 164

Query: 1084 IFFCRNNGWAISTPTAEQFRSDGVVTRGQAY 1176
            I    +N  +ISTP     ++   + +G  Y
Sbjct: 165  IMILNDNEMSISTPIGALSKALSQLMKGPFY 195

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>Q1CUF6:DXS_HELPH 1-deoxy-D-xylulose-5-phosphate synthase - Helicobacter pylori (strain|
            HPAG1)
          Length = 618

 Score = 40.4 bits (93), Expect = 0.024
 Identities = 26/91 (28%), Positives = 42/91 (46%)
 Frame = +1

Query: 904  NYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPM 1083
            +YF ++   +T +   VG A +  + +     I   GDG  S G F+ ALN     + PM
Sbjct: 106  DYF-IAGHSSTSVSIGVGVAKAFCLKQALGMPIALLGDGSISAGIFYEALNELGDRKYPM 164

Query: 1084 IFFCRNNGWAISTPTAEQFRSDGVVTRGQAY 1176
            I    +N  +ISTP     ++   + +G  Y
Sbjct: 165  IMILNDNEMSISTPIGALSKALSQLMKGPFY 195

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>Q47BJ0:DXS_DECAR 1-deoxy-D-xylulose-5-phosphate synthase - Dechloromonas aromatica|
            (strain RCB)
          Length = 618

 Score = 39.7 bits (91), Expect = 0.042
 Identities = 23/65 (35%), Positives = 33/65 (50%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + K   +   AI   GDG  S G    A+N A VA+A M+    +N  
Sbjct: 120  STSISAALGMALAAKHKGEDRKAIAIIGDGAMSAGMAFEAMNNAGVADADMLVILNDNEM 179

Query: 1111 AISTP 1125
            +IS P
Sbjct: 180  SISPP 184

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>Q7VIJ7:DXS_HELHP 1-deoxy-D-xylulose-5-phosphate synthase - Helicobacter hepaticus|
          Length = 629

 Score = 39.3 bits (90), Expect = 0.054
 Identities = 23/74 (31%), Positives = 37/74 (50%)
 Frame = +1

Query: 904  NYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPM 1083
            +YF ++   +T +  AVGAA +L +    +  +   GDG  S G  + ALN     + PM
Sbjct: 121  DYF-IAGHSSTSISLAVGAAKALALKGSASMPVVMIGDGSMSAGLVYEALNELGDKKYPM 179

Query: 1084 IFFCRNNGWAISTP 1125
            +    +N  +IS P
Sbjct: 180  VIILNDNKMSISKP 193

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>Q82VD3:DXS_NITEU 1-deoxy-D-xylulose-5-phosphate synthase - Nitrosomonas europaea|
          Length = 614

 Score = 38.9 bits (89), Expect = 0.071
 Identities = 22/65 (33%), Positives = 33/65 (50%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + ++   K  AI   GDG  S G    ALN A V +A ++    +N  
Sbjct: 118  STSISAALGMAVAARLKGVKQHAIAVIGDGAMSAGMAFEALNNAGVMDANLLVILNDNDM 177

Query: 1111 AISTP 1125
            +IS P
Sbjct: 178  SISPP 182

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>Q8G292:DXS_BRUSU 1-deoxy-D-xylulose-5-phosphate synthase - Brucella suis|
          Length = 643

 Score = 38.9 bits (89), Expect = 0.071
 Identities = 24/88 (27%), Positives = 41/88 (46%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A + ++  +K   I   GDG  S G  + A+N A   +A +I    +N  
Sbjct: 122  STSISAGLGMAVASELSGEKRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDM 181

Query: 1111 AISTPTAEQFRSDGVVTRGQAYGIRSIR 1194
            +I+ PT         +  G+ Y  RS+R
Sbjct: 182  SIAPPTGAMSAYLARLVSGRTY--RSVR 207

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>Q8YFM2:DXS_BRUME 1-deoxy-D-xylulose-5-phosphate synthase - Brucella melitensis|
          Length = 643

 Score = 38.9 bits (89), Expect = 0.071
 Identities = 24/88 (27%), Positives = 41/88 (46%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A + ++  +K   I   GDG  S G  + A+N A   +A +I    +N  
Sbjct: 122  STSISAGLGMAVASELSGEKRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDM 181

Query: 1111 AISTPTAEQFRSDGVVTRGQAYGIRSIR 1194
            +I+ PT         +  G+ Y  RS+R
Sbjct: 182  SIAPPTGAMSAYLARLVSGRTY--RSVR 207

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>Q57ET1:DXS_BRUAB 1-deoxy-D-xylulose-5-phosphate synthase - Brucella abortus|
          Length = 643

 Score = 38.9 bits (89), Expect = 0.071
 Identities = 24/88 (27%), Positives = 41/88 (46%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A + ++  +K   I   GDG  S G  + A+N A   +A +I    +N  
Sbjct: 122  STSISAGLGMAVASELSGEKRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDM 181

Query: 1111 AISTPTAEQFRSDGVVTRGQAYGIRSIR 1194
            +I+ PT         +  G+ Y  RS+R
Sbjct: 182  SIAPPTGAMSAYLARLVSGRTY--RSVR 207

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>Q2YMF0:DXS_BRUA2 1-deoxy-D-xylulose-5-phosphate synthase - Brucella abortus (strain|
            2308)
          Length = 643

 Score = 38.9 bits (89), Expect = 0.071
 Identities = 24/88 (27%), Positives = 41/88 (46%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A + ++  +K   I   GDG  S G  + A+N A   +A +I    +N  
Sbjct: 122  STSISAGLGMAVASELSGEKRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDM 181

Query: 1111 AISTPTAEQFRSDGVVTRGQAYGIRSIR 1194
            +I+ PT         +  G+ Y  RS+R
Sbjct: 182  SIAPPTGAMSAYLARLVSGRTY--RSVR 207

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>Q2KBR2:DXS_RHIEC 1-deoxy-D-xylulose-5-phosphate synthase - Rhizobium etli (strain CFN|
            42 / ATCC 51251)
          Length = 638

 Score = 38.5 bits (88), Expect = 0.093
 Identities = 35/132 (26%), Positives = 53/132 (40%), Gaps = 7/132 (5%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A +  ++K     I   GDG  S G  + ALN A   +A +I    +N  
Sbjct: 123  STSISAGLGMAIAADLEKTDRRVIAVIGDGAMSAGMAYEALNNAGALDARLIVILNDNDM 182

Query: 1111 AISTPTAEQFRSDGVVTRGQAY-GIR------SIRLDGNDTLAVYSAVHTAREMAITEGR 1269
            +I+ PT         +  G+ Y G R      +  L  N   A+  AV  AR      G 
Sbjct: 183  SIAPPTGAMSAYLARLASGRTYMGFRDFGKKLTAYLGKNIDRAITRAVEHAR--GYVTGG 240

Query: 1270 PILIEAMTYRVG 1305
             +  E   Y +G
Sbjct: 241  TMFEEMGFYHIG 252

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>Q11KE0:DXS_MESSB 1-deoxy-D-xylulose-5-phosphate synthase - Mesorhizobium sp. (strain|
            BNC1)
          Length = 650

 Score = 38.5 bits (88), Expect = 0.093
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A + ++   +   I   GDG  S G  + A+N A   +A +I    +N  
Sbjct: 136  STSISAGLGMAVARELSGGQRHVIAVIGDGALSAGMAYEAMNNAGALDARLIVILNDNDM 195

Query: 1111 AISTPTAEQFRSDGVVTRGQAY-GIRSI 1191
            +I+ PT         +  G+AY GIR +
Sbjct: 196  SIAPPTGAMSTYLARLASGRAYRGIRDV 223

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>Q6A6X1:GUAA_PROAC GMP synthase [glutamine-hydrolyzing] - Propionibacterium acnes|
          Length = 530

 Score = 38.1 bits (87), Expect = 0.12
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
 Frame = -1

Query: 1485 NGLQELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCR 1312
            N   E++PH +P   +L+  P +I L+  P SV  +G P   P L     PVLG   G +
Sbjct: 42   NVYSEIVPHNMPVRDMLAKEPAAIILSGGPASVYVEGAPSVDPALFNAGVPVLGICYGFQ 101

Query: 1311 VMADSVG 1291
             MA ++G
Sbjct: 102  AMAQALG 108

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>Q3AD70:GUAA_CARHZ GMP synthase [glutamine-hydrolyzing] - Carboxydothermus|
            hydrogenoformans (strain Z-2901 / DSM 6008)
          Length = 509

 Score = 37.7 bits (86), Expect = 0.16
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
 Frame = -1

Query: 1473 ELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCRVMAD 1300
            E+LP+  P  +++   P  I  +  P SV G+G P   P ++ ++ P+LG   G ++MA 
Sbjct: 30   EMLPYNTPLEKIVQENPGGIVFSGGPSSVYGEGAPTVDPEIYRLNIPILGICYGMQLMAH 89

Query: 1299 SVG 1291
             +G
Sbjct: 90   QLG 92

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>Q5HWF0:DXS_CAMJR 1-deoxy-D-xylulose-5-phosphate synthase - Campylobacter jejuni|
            (strain RM1221)
          Length = 615

 Score = 37.7 bits (86), Expect = 0.16
 Identities = 22/74 (29%), Positives = 37/74 (50%)
 Frame = +1

Query: 904  NYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPM 1083
            +YF V+   +T +  AVGA  ++ +  +K   +   GDG  S G  + ALN    ++ P 
Sbjct: 106  DYF-VAGHSSTSISLAVGACKAIALKGEKRIPVALIGDGALSAGMAYEALNELGDSKFPC 164

Query: 1084 IFFCRNNGWAISTP 1125
            +    +N  +IS P
Sbjct: 165  VILLNDNEMSISKP 178

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>Q9PIH8:DXS_CAMJE 1-deoxy-D-xylulose-5-phosphate synthase - Campylobacter jejuni|
          Length = 615

 Score = 37.7 bits (86), Expect = 0.16
 Identities = 22/74 (29%), Positives = 37/74 (50%)
 Frame = +1

Query: 904  NYFTVSSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPM 1083
            +YF V+   +T +  AVGA  ++ +  +K   +   GDG  S G  + ALN    ++ P 
Sbjct: 106  DYF-VAGHSSTSISLAVGACKAIALKGEKRIPVALIGDGALSAGMAYEALNELGDSKFPC 164

Query: 1084 IFFCRNNGWAISTP 1125
            +    +N  +IS P
Sbjct: 165  VILLNDNEMSISKP 178

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>Q4FN07:DXS_PELUB 1-deoxy-D-xylulose-5-phosphate synthase - Pelagibacter ubique|
          Length = 637

 Score = 37.4 bits (85), Expect = 0.21
 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 10/112 (8%)
 Frame = +1

Query: 820  EFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPI----------ATQLPQAVGAAYS 969
            +  +Q + +K+  G+  ++      N L+ FT  S            +T +  A+G A +
Sbjct: 73   DVGHQTYPHKILTGRKSKIKTLRQGNGLSGFTKRSESEYDPFGAAHSSTSISSALGMAEA 132

Query: 970  LKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTP 1125
             K+  K    I   GDG  S G  + A+N A  ++  MI    +N  +I+ P
Sbjct: 133  NKLSNKLNNIIAVIGDGAISAGMAYEAMNNAGASKTKMIVILNDNDMSIAKP 184

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>O22567:DXS_ORYSJ Probable 1-deoxy-D-xylulose-5-phosphate synthase, chloroplast|
            precursor - Oryza sativa subsp. japonica (Rice)
          Length = 720

 Score = 37.4 bits (85), Expect = 0.21
 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 10/116 (8%)
 Frame = +1

Query: 814  LQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPI----------ATQLPQAVGAA 963
            L +  +Q + +K+  G+  +MP    +N L+ FT  S            +T +  A+G A
Sbjct: 137  LWDVGHQSYPHKILTGRRDKMPTMRQTNGLSGFTKRSESEYDSFGTGHSSTTISAALGMA 196

Query: 964  YSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTA 1131
                +   K   +   GDG  + G  + A+N A   ++ MI    +N   +S PTA
Sbjct: 197  VGRDLKGGKNNVVAVIGDGAMTAGQAYEAMNNAGYLDSDMIVILNDNK-QVSLPTA 251

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>Q58094:TKTN_METJA Putative transketolase N-terminal section - Methanococcus jannaschii|
          Length = 274

 Score = 37.0 bits (84), Expect = 0.27
 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 1/118 (0%)
 Frame = +1

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEG-DFHAALNFAAVAEAPMIFFCRNNGWAISTP 1125
            AVG A   ++DK         GDG   EG  + AA+  A      +I F   N   I   
Sbjct: 127  AVGMALGCRLDKLNNYVYVLLGDGECQEGIVWEAAMAAAHYKLDNLIAFIDRNKLQIDGC 186

Query: 1126 TAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYR 1299
            T +      +  + +A+G     +DG++   + + V  A+ M    G+P +I A T +
Sbjct: 187  TEDVMSLGDIKAKFEAFGWDVFEIDGHNFEEIINTVEKAKSM--KNGKPKMIIAYTVK 242

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>Q60AN1:DXS_METCA 1-deoxy-D-xylulose-5-phosphate synthase - Methylococcus capsulatus|
          Length = 639

 Score = 37.0 bits (84), Expect = 0.27
 Identities = 18/63 (28%), Positives = 33/63 (52%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A +  ++++   A+   GDGG + G    ALN A   +A ++    +N  
Sbjct: 123  STSISAALGMAVAAALERRPIHAVAIIGDGGLTGGMAFEALNHAGTLDANLLIILNDNEM 182

Query: 1111 AIS 1119
            +IS
Sbjct: 183  SIS 185

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>Q47LQ0:GUAA_THEFY GMP synthase [glutamine-hydrolyzing] - Thermobifida fusca (strain YX)|
          Length = 528

 Score = 36.6 bits (83), Expect = 0.35
 Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
 Frame = -1

Query: 1473 ELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCRVMAD 1300
            E++P  +P   +L+  P +I L+  P SV  DG P   P L     P+LG   G +VMA 
Sbjct: 39   EIVPPTMPVEEMLAKKPKAIILSGGPSSVYADGAPQAPPGLFDTGVPILGICYGFQVMAQ 98

Query: 1299 SVG 1291
            ++G
Sbjct: 99   TLG 101

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>Q2YCH7:DXS_NITMU 1-deoxy-D-xylulose-5-phosphate synthase - Nitrosospira multiformis|
            (strain ATCC 25196 / NCIMB 11849)
          Length = 614

 Score = 36.6 bits (83), Expect = 0.35
 Identities = 19/65 (29%), Positives = 31/65 (47%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + + + KK   +   GDG  S G    ALN A   +  ++    +N  
Sbjct: 118  STSISAALGMAVASQWEGKKRSVVAVIGDGAMSAGMAFEALNNAGAMDTNLLVILNDNDM 177

Query: 1111 AISTP 1125
            +IS P
Sbjct: 178  SISRP 182

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>Q2NKZ4:TKTL2_BOVIN Transketolase-like protein 2 - Bos taurus (Bovine)|
          Length = 626

 Score = 36.2 bits (82), Expect = 0.46
 Identities = 41/139 (29%), Positives = 63/139 (45%), Gaps = 5/139 (3%)
 Frame = +1

Query: 898  RLNYFTVSSPIATQ-LPQAVGAAYSLK-MDKKKACAITYFGDGGTSEGDFHAALNFAA-- 1065
            RL++  V++    Q L  A G AY+ K +DK         GDG +SEG    AL FA+  
Sbjct: 114  RLSFVDVATGSLGQGLGAACGMAYTGKYLDKASYRVFCLLGDGESSEGSVWEALAFASHY 173

Query: 1066 -VAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTA 1242
             +     +F     G +   P   +  +D    R +A+G  +  +DG+D  A+  A   A
Sbjct: 174  GLDNLVAVFDVNRLGQSGVAPL--KHCTDIYRNRCEAFGWNTYLVDGHDVEALCQAFSQA 231

Query: 1243 REMAITEGRPILIEAMTYR 1299
               A  + +P  I A TY+
Sbjct: 232  ---AQGKNKPTAIIAKTYK 247

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>Q8XX95:DXS_RALSO 1-deoxy-D-xylulose-5-phosphate synthase - Ralstonia solanacearum|
            (Pseudomonas solanacearum)
          Length = 636

 Score = 36.2 bits (82), Expect = 0.46
 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 1/83 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAV-AEAPMIFFCRNNG 1107
            +T +  A+G A   K   +   AI   GDG  S G    A+N A V    P++    +N 
Sbjct: 119  STSISAALGMALGAKTQGENRVAIAVIGDGAMSAGMAFEAMNNAGVYRNLPLVVVLNDND 178

Query: 1108 WAISTPTAEQFRSDGVVTRGQAY 1176
             +IS P     R    +  GQ Y
Sbjct: 179  MSISPPVGALNRYLARLMSGQFY 201

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>Q9KGU7:DXS_PSEAE 1-deoxy-D-xylulose-5-phosphate synthase - Pseudomonas aeruginosa|
          Length = 627

 Score = 36.2 bits (82), Expect = 0.46
 Identities = 18/63 (28%), Positives = 33/63 (52%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + ++  K+  ++   GDG  + G    ALN A+  +A M+    +N  
Sbjct: 131  STSISAALGMAIAARLQGKERKSVAVIGDGALTAGMAFEALNHASEVDADMLVILNDNDM 190

Query: 1111 AIS 1119
            +IS
Sbjct: 191  SIS 193

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>Q3JDG3:GUAA_NITOC GMP synthase [glutamine-hydrolyzing] - Nitrosococcus oceani (strain|
            ATCC 19707 / NCIMB 11848)
          Length = 524

 Score = 35.8 bits (81), Expect = 0.60
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
 Frame = -1

Query: 1473 ELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCRVMAD 1300
            E+ P+ + E  L   AP  I L+  P S  G+  P  SP++  +  P+LG   G +VMA 
Sbjct: 34   EIHPYDMAESTLRDFAPRGIILSGGPASTVGETAPRLSPLIFELGVPLLGICYGMQVMAA 93

Query: 1299 SVGHRLD 1279
             +G R++
Sbjct: 94   QLGGRVE 100

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>Q7M7Z0:DXS_WOLSU 1-deoxy-D-xylulose-5-phosphate synthase - Wolinella succinogenes|
          Length = 619

 Score = 35.8 bits (81), Expect = 0.60
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +1

Query: 904  NYFTVSSPIATQLPQAVGAAYSLKMD-KKKACAITYFGDGGTSEGDFHAALNFAAVAEAP 1080
            +YF ++   +T +  AVGAA ++ +  +K    +   GDG  S G  + ALN     + P
Sbjct: 99   DYF-IAGHSSTSISLAVGAAKAISLSLEKNRMPVVLIGDGSMSAGLCYEALNELGDRKYP 157

Query: 1081 MIFFCRNNGWAISTP 1125
            M+    +N  +I+ P
Sbjct: 158  MVILLNDNEMSIAEP 172

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>Q8UHD7:DXS_AGRT5 1-deoxy-D-xylulose-5-phosphate synthase - Agrobacterium tumefaciens|
            (strain C58 / ATCC 33970)
          Length = 639

 Score = 35.8 bits (81), Expect = 0.60
 Identities = 22/82 (26%), Positives = 34/82 (41%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A +  +D      I   GDG  S G    ALN A   +A +I    +N  
Sbjct: 123  STSISAGLGMAVAAGLDGSDRKVIAVIGDGSMSAGMAFEALNNAGALDARLIVILNDNDM 182

Query: 1111 AISTPTAEQFRSDGVVTRGQAY 1176
            +I+ PT         +  G+ Y
Sbjct: 183  SIAPPTGAMSAYLARLASGRTY 204

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>P22976:TKT_STRPN Probable transketolase - Streptococcus pneumoniae|
          Length = 658

 Score = 35.4 bits (80), Expect = 0.78
 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 1/108 (0%)
 Frame = +1

Query: 1012 GDGGTSEGDFHAALNFAAVAEAP-MIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRS 1188
            GDG   EG    A ++A + +   ++    +N   +   T + F ++ V  R  AYG  +
Sbjct: 153  GDGDLMEGVSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSF-TESVRDRYNAYGWHT 211

Query: 1189 IRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYRVGHHSTSDDST 1332
              ++    L    A+H A E A   G+P LIE  T  +G+ S +   T
Sbjct: 212  ALVENGTDL---EAIHAAIETAKASGKPSLIEVKTV-IGYGSPNKQGT 255

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>Q985Y3:DXS_RHILO 1-deoxy-D-xylulose-5-phosphate synthase - Rhizobium loti|
            (Mesorhizobium loti)
          Length = 637

 Score = 35.4 bits (80), Expect = 0.78
 Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A +  +   +   I   GDG  S G  + A+N A   +A +I    +N  
Sbjct: 123  STSISAGLGMAAARDLSGGRNNVIAVIGDGAMSAGMAYEAMNNAGALDARLIVILNDNDM 182

Query: 1111 AISTPTAEQFRSDGVVTRGQAY-GIR 1185
            +I+ PT         +  G+AY G+R
Sbjct: 183  SIAPPTGAMSAYLARLASGKAYAGLR 208

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>Q4K5A5:DXS_PSEF5 1-deoxy-D-xylulose-5-phosphate synthase - Pseudomonas fluorescens|
            (strain Pf-5 / ATCC BAA-477)
          Length = 633

 Score = 35.4 bits (80), Expect = 0.78
 Identities = 19/63 (30%), Positives = 31/63 (49%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + ++   +  AI   GDG  + G    ALN A   +A M+    +N  
Sbjct: 131  STSISAALGMAIAARLQNSERKAIAVIGDGALTAGMAFEALNHAPEVDANMLVILNDNDM 190

Query: 1111 AIS 1119
            +IS
Sbjct: 191  SIS 193

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>Q2SA08:DXS_HAHCH 1-deoxy-D-xylulose-5-phosphate synthase - Hahella chejuensis (strain|
            KCTC 2396)
          Length = 643

 Score = 35.4 bits (80), Expect = 0.78
 Identities = 19/63 (30%), Positives = 32/63 (50%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + ++  +   AI   GDG  + G    ALN AA  +A ++    +N  
Sbjct: 133  STSISAALGMAIAARLQNQPRKAIAVIGDGAMTAGMAFEALNHAADTKADLLVILNDNDM 192

Query: 1111 AIS 1119
            +IS
Sbjct: 193  SIS 195

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>Q38854:DXS_ARATH Probable 1-deoxy-D-xylulose-5-phosphate synthase, chloroplast|
            precursor - Arabidopsis thaliana (Mouse-ear cress)
          Length = 717

 Score = 35.4 bits (80), Expect = 0.78
 Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 10/116 (8%)
 Frame = +1

Query: 814  LQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTV----------SSPIATQLPQAVGAA 963
            L +  +Q + +K+  G+  +MP    +N L+ FT           +   +T +   +G A
Sbjct: 141  LWDVGHQSYPHKILTGRRGKMPTMRQTNGLSGFTKRGESEHDCFGTGHSSTTISAGLGMA 200

Query: 964  YSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTA 1131
                +  K    +   GDG  + G  + A+N A   ++ MI    +N   +S PTA
Sbjct: 201  VGRDLKGKNNNVVAVIGDGAMTAGQAYEAMNNAGYLDSDMIVILNDNK-QVSLPTA 255

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>Q5R1W6:TKT_PANTR Transketolase - Pan troglodytes (Chimpanzee)|
          Length = 623

 Score = 35.0 bits (79), Expect = 1.0
 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 2/122 (1%)
 Frame = +1

Query: 940  LPQAVGAAYSLK-MDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP-MIFFCRNNGWA 1113
            L  A G AY+ K  DK         GDG  SEG    A+ FA++ +   ++     N   
Sbjct: 129  LGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLG 188

Query: 1114 ISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMT 1293
             S P   Q + D    R +A+G  +I +DG+    +  A   A+       +P  I A T
Sbjct: 189  QSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKH------QPTAIIAKT 242

Query: 1294 YR 1299
            ++
Sbjct: 243  FK 244

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>P29401:TKT_HUMAN Transketolase - Homo sapiens (Human)|
          Length = 623

 Score = 35.0 bits (79), Expect = 1.0
 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 2/122 (1%)
 Frame = +1

Query: 940  LPQAVGAAYSLK-MDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP-MIFFCRNNGWA 1113
            L  A G AY+ K  DK         GDG  SEG    A+ FA++ +   ++     N   
Sbjct: 129  LGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLG 188

Query: 1114 ISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMT 1293
             S P   Q + D    R +A+G  +I +DG+    +  A   A+       +P  I A T
Sbjct: 189  QSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKH------QPTAIIAKT 242

Query: 1294 YR 1299
            ++
Sbjct: 243  FK 244

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>Q7UFS3:GUAA_RHOBA GMP synthase [glutamine-hydrolyzing] - Rhodopirellula baltica|
          Length = 587

 Score = 35.0 bits (79), Expect = 1.0
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
 Frame = -1

Query: 1473 ELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCRVMAD 1300
            +++ H +   R+   AP  I L+  P SV  +G P C   L  +  PVLG   G ++   
Sbjct: 105  QIVRHDISAERIAELAPKGIILSGGPNSVYEEGAPKCDEGLFDLGIPVLGICYGMQLACQ 164

Query: 1299 SVGHRLD*NRPSFSY 1255
            ++G ++D N PS  Y
Sbjct: 165  ALGGKVD-NTPSREY 178

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>Q8G5P4:GUAA_BIFLO GMP synthase [glutamine-hydrolyzing] - Bifidobacterium longum|
          Length = 535

 Score = 35.0 bits (79), Expect = 1.0
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
 Frame = -1

Query: 1473 ELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCRVMAD 1300
            EL+PH +P   +L+  P +I L+  P SV   G P     +     PVLG   G +VMA 
Sbjct: 46   ELVPHSMPVDEILAKDPKAIILSGGPASVFEPGAPTIDTKVFESGVPVLGICYGFQVMAY 105

Query: 1299 SVGHRLD 1279
             +G ++D
Sbjct: 106  ELGGKVD 112

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>Q30TC5:DXS_THIDN 1-deoxy-D-xylulose-5-phosphate synthase - Thiomicrospira|
            denitrificans (strain ATCC 33889 / DSM 1351)
          Length = 606

 Score = 35.0 bits (79), Expect = 1.0
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
 Frame = +1

Query: 904  NYFTVSSPIATQLPQAVGAA--YSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEA 1077
            +YF V+   +T +   VGAA   +LK ++     +   GDG  + G  + ALN     + 
Sbjct: 99   DYF-VAGHSSTSISLGVGAAKAIALKGEQNSRIPVIMIGDGSMTAGMVYEALNELGERKY 157

Query: 1078 PMIFFCRNNGWAISTP 1125
            PM+    +N  +IS P
Sbjct: 158  PMVIILNDNEMSISKP 173

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>Q21F93:DXS_SACD2 1-deoxy-D-xylulose-5-phosphate synthase - Saccharophagus degradans|
            (strain 2-40 / ATCC 43961 / DSM 17024)
          Length = 649

 Score = 35.0 bits (79), Expect = 1.0
 Identities = 19/63 (30%), Positives = 31/63 (49%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + +M   +   +   GDG  + G    ALN AA A+  M+    +N  
Sbjct: 128  STSISAALGMALAAEMTDNQQQTVAVIGDGSMTAGMAFEALNHAAHADTNMMVILNDNNM 187

Query: 1111 AIS 1119
            +IS
Sbjct: 188  SIS 190

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>Q6NB76:DXS_RHOPA 1-deoxy-D-xylulose-5-phosphate synthase - Rhodopseudomonas palustris|
          Length = 641

 Score = 35.0 bits (79), Expect = 1.0
 Identities = 24/91 (26%), Positives = 40/91 (43%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +   +G A + ++  KK   I   GDG  S G  + A+N A    + +I    +N  
Sbjct: 123  STSISAGLGMAVASELAGKKNNVIAVIGDGSISAGMAYEAMNNAGAMNSRLIVILNDNNM 182

Query: 1111 AISTPTAEQFRSDGVVTRGQAYGIRSIRLDG 1203
            +I+ P          +  G+ Y  RS+R  G
Sbjct: 183  SIAPPVGAMSAYLSRLYSGKTY--RSLREAG 211

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>Q16DV7:DXS1_ROSDO 1-deoxy-D-xylulose-5-phosphate synthase 1 - Roseobacter denitrificans|
            (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain
            OCh 114)) (Roseobacter denitrificans)
          Length = 645

 Score = 35.0 bits (79), Expect = 1.0
 Identities = 37/160 (23%), Positives = 63/160 (39%), Gaps = 16/160 (10%)
 Frame = +1

Query: 820  EFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPI----------ATQLPQAVGAAYS 969
            +  +Q + +K+  G+ +QMP       ++ FT  S            +T +  A+G   S
Sbjct: 75   DVGHQCYPHKILTGRRKQMPTLRQGGGISGFTKRSESEYDPFGAAHSSTSISAALGFTIS 134

Query: 970  LKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT---AEQF 1140
              M +    A+   GDG  S G  + A+N A      M     +N  +I+ P    +   
Sbjct: 135  RDMGQPTGDAVAVIGDGSISAGMAYEAMNNAGHEGRRMFVILNDNEMSIAPPVGAMSSYL 194

Query: 1141 RSDGVVTRGQAYGIRSIRLDGNDTLA---VYSAVHTAREM 1251
             S   ++R   +G      +G + LA   V      ARE+
Sbjct: 195  SSLSELSRAGPFGGLVAIAEGMEQLAPKPVRDGARRAREL 234

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>P50137:TKT_RAT Transketolase - Rattus norvegicus (Rat)|
          Length = 623

 Score = 34.7 bits (78), Expect = 1.3
 Identities = 34/122 (27%), Positives = 51/122 (41%), Gaps = 2/122 (1%)
 Frame = +1

Query: 940  LPQAVGAAYSLK-MDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP-MIFFCRNNGWA 1113
            L  A G AY+ K  DK         GDG  SEG    A+ FA + +   ++     N   
Sbjct: 129  LGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLG 188

Query: 1114 ISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMT 1293
             S P   Q + D    R +A+G  +I +DG+    +  A   A+       +P  I A T
Sbjct: 189  QSDPAPLQHQVDVYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKH------QPTAIIAKT 242

Query: 1294 YR 1299
            ++
Sbjct: 243  FK 244

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>Q6B855:TKT_BOVIN Transketolase - Bos taurus (Bovine)|
          Length = 623

 Score = 34.7 bits (78), Expect = 1.3
 Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 2/122 (1%)
 Frame = +1

Query: 940  LPQAVGAAYSLK-MDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP-MIFFCRNNGWA 1113
            L  A G AY+ K  DK         GDG  SEG    A+ FA++ +   ++     N   
Sbjct: 129  LGAACGMAYTGKYFDKASYRVYCMLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLG 188

Query: 1114 ISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMT 1293
             S P   Q + D    R +A+G  ++ +DG      +S     +     + +P  I A T
Sbjct: 189  QSDPAPLQHQMDIYQKRCEAFGWNAVIVDG------HSVEELCKAFGQVKNQPTAIIAKT 242

Query: 1294 YR 1299
            ++
Sbjct: 243  FK 244

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>Q3K660:DXS_PSEPF 1-deoxy-D-xylulose-5-phosphate synthase - Pseudomonas fluorescens|
            (strain PfO-1)
          Length = 632

 Score = 34.7 bits (78), Expect = 1.3
 Identities = 19/63 (30%), Positives = 30/63 (47%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + ++      AI   GDG  + G    ALN A   +A M+    +N  
Sbjct: 131  STSISAALGMAIAARLQNSDRKAIAVIGDGALTAGMAFEALNHAPEVDANMLVILNDNDM 190

Query: 1111 AIS 1119
            +IS
Sbjct: 191  SIS 193

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>P55574:Y4MO_RHISN Putative uncharacterized transketolase family protein y4mO -|
            Rhizobium sp. (strain NGR234)
          Length = 279

 Score = 34.3 bits (77), Expect = 1.7
 Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 1/113 (0%)
 Frame = +1

Query: 949  AVGAAYSLKMDKKKACAITYFGDGGTSEGD-FHAALNFAAVAEAPMIFFCRNNGWAISTP 1125
            AVG + +LK    ++     F DG   EG  + AA++  +     +I     N      P
Sbjct: 128  AVGMSLALKRKGSRSFVYNLFSDGELDEGSTWEAAMSAGSYKLDNLIGIVDVNQMQADGP 187

Query: 1126 TAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIE 1284
            +      + +  + +A+G    R+DGND  A+  A   AR+    + R I+ +
Sbjct: 188  SLGVLNFEPLGPKFEAFGWYVQRIDGNDIDALVDAFDNARQHRHPQPRIIICD 240

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>Q5R4C1:TKT_PONPY Transketolase - Pongo pygmaeus (Orangutan)|
          Length = 623

 Score = 34.3 bits (77), Expect = 1.7
 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 2/119 (1%)
 Frame = +1

Query: 949  AVGAAYSLK-MDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP-MIFFCRNNGWAIST 1122
            A G AY+ K  DK         GDG  SEG    A+ FA++ +   ++     N    S 
Sbjct: 132  ACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSD 191

Query: 1123 PTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTYR 1299
            P   Q + D    R +A+G  ++ +DG+    +  A   A+       +P  I A T++
Sbjct: 192  PAPLQHQMDIYQKRCEAFGWHAVIVDGHSVEELCKAFGQAKH------QPTAIIAKTFK 244

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>P40142:TKT_MOUSE Transketolase - Mus musculus (Mouse)|
          Length = 623

 Score = 34.3 bits (77), Expect = 1.7
 Identities = 34/122 (27%), Positives = 51/122 (41%), Gaps = 2/122 (1%)
 Frame = +1

Query: 940  LPQAVGAAYSLK-MDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP-MIFFCRNNGWA 1113
            L  A G AY+ K  DK         GDG  SEG    A+ FA + +   ++     N   
Sbjct: 129  LGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLG 188

Query: 1114 ISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMT 1293
             S P   Q + D    R +A+G  +I +DG+    +  A   A+       +P  I A T
Sbjct: 189  QSDPAPLQHQVDIYQKRCEAFGWHTIIVDGHSVEELCKAFGQAKH------QPTAIIAKT 242

Query: 1294 YR 1299
            ++
Sbjct: 243  FK 244

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>Q60HC7:TKT_MACFA Transketolase - Macaca fascicularis (Crab eating macaque) (Cynomolgus|
            monkey)
          Length = 623

 Score = 34.3 bits (77), Expect = 1.7
 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 2/122 (1%)
 Frame = +1

Query: 940  LPQAVGAAYSLK-MDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP-MIFFCRNNGWA 1113
            L  A G AY+ K  DK         GDG  SEG    A+ FA++ +   ++     N   
Sbjct: 129  LGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLG 188

Query: 1114 ISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMT 1293
             S P   Q + D    R +A+G  +I +DG+    +  A   A+       +P  I A T
Sbjct: 189  QSDPAPLQHQMDIHQKRCEAFGWHAIIVDGHSVEELCKAFGQAKH------QPTAIIAKT 242

Query: 1294 YR 1299
            ++
Sbjct: 243  FK 244

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>Q9D4D4:TKTL2_MOUSE Transketolase-like protein 2 - Mus musculus (Mouse)|
          Length = 627

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 5/139 (3%)
 Frame = +1

Query: 898  RLNYFTVSSPIATQ-LPQAVGAAYSLK-MDKKKACAITYFGDGGTSEGDFHAALNFAA-- 1065
            RL++  V++    Q L  A G AY+ K  DK         GDG +SEG    AL FA+  
Sbjct: 116  RLSFVDVATGSLGQGLGAACGMAYTGKYFDKASYRVFCLMGDGESSEGSVWEALAFASHY 175

Query: 1066 -VAEAPMIFFCRNNGWAISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTA 1242
             +     IF     G + + P   +  +     R QA+G  +  +DG+D  A+  A   A
Sbjct: 176  NLDNLVAIFDVNRLGQSGTAPL--EHCTAVYEKRCQAFGWNTYVVDGHDVEALCQAFWKA 233

Query: 1243 REMAITEGRPILIEAMTYR 1299
             ++   + +P  + A T++
Sbjct: 234  AQV---KNKPTALIAKTFK 249

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>Q8NRC3:ODO1_CORGL 2-oxoglutarate dehydrogenase E1 component - Corynebacterium|
            glutamicum (Brevibacterium flavum)
          Length = 1257

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
 Frame = +1

Query: 1120 TPTAEQFRSDGVVTR-GQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMTY 1296
            T T +  RS    T   +A+G     ++G+D  AV      A E     G+ + I+ + Y
Sbjct: 719  TTTPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWVGQLATEYRRRFGKDVFIDLVCY 778

Query: 1297 RVGHHSTSDDSTKYRPADEMEHWRTARDPV-SRYRKWVQGNG 1419
            R+  H+ +DD +  +P  +M    T R+ V ++Y + + G G
Sbjct: 779  RLRGHNEADDPSMTQP--KMYELITGRETVRAQYTEDLLGRG 818

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>Q1GQK9:DXS_SPHAL 1-deoxy-D-xylulose-5-phosphate synthase - Sphingopyxis alaskensis|
            (Sphingomonas alaskensis)
          Length = 642

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 20/65 (30%), Positives = 32/65 (49%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + K+  +   AI   GDG  S G  + A+N A  A   +I    +N  
Sbjct: 123  STSISAALGFAIANKLKDEPGRAIAVIGDGSMSAGMAYEAMNNAKQAGNRLIVILNDNDM 182

Query: 1111 AISTP 1125
            +I+ P
Sbjct: 183  SIAPP 187

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>Q1LK34:DXS_RALME 1-deoxy-D-xylulose-5-phosphate synthase - Ralstonia metallidurans|
            (strain CH34 / ATCC 43123 / DSM 2839)
          Length = 637

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAV-AEAPMIFFCRNNG 1107
            +T +  A+G A   +   +K   I   GDG  + G    A+N A V  + PM+    +N 
Sbjct: 119  STSISAALGMALGARTRGEKRVGIAVIGDGAMTAGMAFEAMNNAGVYKDLPMLVVLNDND 178

Query: 1108 WAISTPTAEQFRSDGVVTRGQAY 1176
             +IS P     +    +  GQ Y
Sbjct: 179  MSISPPVGMLNKHLARLMSGQFY 201

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>Q1D3G4:DXS_MYXXD 1-deoxy-D-xylulose-5-phosphate synthase - Myxococcus xanthus (strain|
            DK 1622)
          Length = 583

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 29/127 (22%), Positives = 51/127 (40%), Gaps = 5/127 (3%)
 Frame = +1

Query: 934  TQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWA 1113
            T +  A+G     +    +   +   GDGG + G     LN A  +  P++    +N  +
Sbjct: 119  TAVSAALGVLEGRRQQGHRGHVVAVLGDGGLTGGLTFEGLNNAGGSSLPLVVVLNDNQMS 178

Query: 1114 IST-----PTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPIL 1278
            IS      P   + R       G  +      +DG+D  A+  A+  AR       RP++
Sbjct: 179  ISANVGAIPALLRTREARDFFEGLGFTYLG-PVDGHDLPALIRALREAR----ASSRPVV 233

Query: 1279 IEAMTYR 1299
            + A+T +
Sbjct: 234  VHALTLK 240

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>Q2T7N5:DXS_BURTA 1-deoxy-D-xylulose-5-phosphate synthase - Burkholderia thailandensis|
            (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)
          Length = 634

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAE-APMIFFCRNNG 1107
            +T +  A+G A   K++     +I   GDG  + G    A+N A V+E A ++    +N 
Sbjct: 118  STSISAALGMAIGSKLNGDDRFSIAVIGDGAMTAGMAFEAMNNAGVSEDAKLLVILNDND 177

Query: 1108 WAISTPTAEQFRSDGVVTRGQAY 1176
             +IS P     R    +  G+ Y
Sbjct: 178  MSISPPVGALNRHLARLMSGRFY 200

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>Q63JF4:DXS_BURPS 1-deoxy-D-xylulose-5-phosphate synthase - Burkholderia pseudomallei|
            (Pseudomonas pseudomallei)
          Length = 634

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAE-APMIFFCRNNG 1107
            +T +  A+G A   K++     +I   GDG  + G    A+N A V+E A ++    +N 
Sbjct: 118  STSISAALGMAIGSKLNGDDRFSIAVIGDGAMTAGMAFEAMNNAGVSEDAKLLVILNDND 177

Query: 1108 WAISTPTAEQFRSDGVVTRGQAY 1176
             +IS P     R    +  G+ Y
Sbjct: 178  MSISPPVGALNRHLARLMSGRFY 200

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>Q3JKA3:DXS_BURP1 1-deoxy-D-xylulose-5-phosphate synthase - Burkholderia pseudomallei|
            (strain 1710b)
          Length = 634

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAE-APMIFFCRNNG 1107
            +T +  A+G A   K++     +I   GDG  + G    A+N A V+E A ++    +N 
Sbjct: 118  STSISAALGMAIGSKLNGDDRFSIAVIGDGAMTAGMAFEAMNNAGVSEDAKLLVILNDND 177

Query: 1108 WAISTPTAEQFRSDGVVTRGQAY 1176
             +IS P     R    +  G+ Y
Sbjct: 178  MSISPPVGALNRHLARLMSGRFY 200

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>Q62DU1:DXS_BURMA 1-deoxy-D-xylulose-5-phosphate synthase - Burkholderia mallei|
            (Pseudomonas mallei)
          Length = 634

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAE-APMIFFCRNNG 1107
            +T +  A+G A   K++     +I   GDG  + G    A+N A V+E A ++    +N 
Sbjct: 118  STSISAALGMAIGSKLNGDDRFSIAVIGDGAMTAGMAFEAMNNAGVSEDAKLLVILNDND 177

Query: 1108 WAISTPTAEQFRSDGVVTRGQAY 1176
             +IS P     R    +  G+ Y
Sbjct: 178  MSISPPVGALNRHLARLMSGRFY 200

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>Q6G0D4:DXS_BARQU 1-deoxy-D-xylulose-5-phosphate synthase - Bartonella quintana|
            (Rochalimaea quintana)
          Length = 640

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 23/70 (32%), Positives = 36/70 (51%)
 Frame = +1

Query: 919  SSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCR 1098
            S+ I+  L   V +A  LK +K++   I   GDG  S G  + A+N A   +A +I    
Sbjct: 122  STSISAGLGMTVASA--LKAEKRRNI-IAVIGDGAMSAGMAYEAMNNAGALDARLIVILN 178

Query: 1099 NNGWAISTPT 1128
            +N  +I+ PT
Sbjct: 179  DNDMSIAPPT 188

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>Q6G4D1:DXS_BARHE 1-deoxy-D-xylulose-5-phosphate synthase - Bartonella henselae|
            (Rochalimaea henselae)
          Length = 640

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 23/70 (32%), Positives = 36/70 (51%)
 Frame = +1

Query: 919  SSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCR 1098
            S+ I+  L  AV +A  LK +K++   +   GDG  S G  + A+N A    A +I    
Sbjct: 122  STSISAGLGMAVASA--LKAEKRRNI-VAVIGDGAMSAGMAYEAMNNAGALNARLIVVLN 178

Query: 1099 NNGWAISTPT 1128
            +N  +I+ PT
Sbjct: 179  DNDMSIAPPT 188

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>Q5NM38:DXS2_ZYMMO 1-deoxy-D-xylulose-5-phosphate synthase 2 - Zymomonas mobilis|
          Length = 650

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 19/65 (29%), Positives = 31/65 (47%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + K+      A+   GDG  + G  + A+N A  A   +I    +N  
Sbjct: 123  STSISAALGFAMASKLSDSDDKAVAIIGDGSMTAGMAYEAMNNAKAAGKRLIVILNDNEM 182

Query: 1111 AISTP 1125
            +IS P
Sbjct: 183  SISPP 187

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>Q5NN52:DXS1_ZYMMO 1-deoxy-D-xylulose-5-phosphate synthase 1 - Zymomonas mobilis|
          Length = 649

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 19/65 (29%), Positives = 31/65 (47%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + K+      A+   GDG  + G  + A+N A  A   +I    +N  
Sbjct: 123  STSISAALGFAMASKLSDSDDKAVAIIGDGSMTAGMAYEAMNNAKAAGKRLIVILNDNEM 182

Query: 1111 AISTP 1125
            +IS P
Sbjct: 183  SISPP 187

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>Q8PXG9:RBL_METMA Ribulose bisphosphate carboxylase - Methanosarcina mazei|
            (Methanosarcina frisia)
          Length = 428

 Score = 33.5 bits (75), Expect = 3.0
 Identities = 23/74 (31%), Positives = 35/74 (47%)
 Frame = -1

Query: 1458 IVPELRLLSTAPPSIPLNPFSVPGDGIPCCSPMLHLISRPVLG*IVGCRVMADSVGHRLD 1279
            IV  +RL   A P   +N F  P  G+P    ++ +  RP++G IV  +V  +S  H   
Sbjct: 105  IVDNVRLQDIAFPKSMINEFKGPNFGLPGIRKLVGVQDRPLIGTIVKPKVGLNSEKH--- 161

Query: 1278 *NRPSFSYSHFPGG 1237
                  +Y+ F GG
Sbjct: 162  ---AEVAYNSFVGG 172

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>P0A5A1:GUAA_MYCTU GMP synthase [glutamine-hydrolyzing] - Mycobacterium tuberculosis|
          Length = 525

 Score = 33.5 bits (75), Expect = 3.0
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
 Frame = -1

Query: 1473 ELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCRVMAD 1300
            E++PH      + +  P ++ L+  P SV  DG P   P L  +  PVLG   G + MA 
Sbjct: 42   EVIPHTASIEEIRARQPVALVLSGGPASVYADGAPKLDPALLDLGVPVLGICYGFQAMAQ 101

Query: 1299 SVG 1291
            ++G
Sbjct: 102  ALG 104

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>P0A5A2:GUAA_MYCBO GMP synthase [glutamine-hydrolyzing] - Mycobacterium bovis|
          Length = 525

 Score = 33.5 bits (75), Expect = 3.0
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
 Frame = -1

Query: 1473 ELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCRVMAD 1300
            E++PH      + +  P ++ L+  P SV  DG P   P L  +  PVLG   G + MA 
Sbjct: 42   EVIPHTASIEEIRARQPVALVLSGGPASVYADGAPKLDPALLDLGVPVLGICYGFQAMAQ 101

Query: 1299 SVG 1291
            ++G
Sbjct: 102  ALG 104

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>Q2GC13:DXS_NOVAD 1-deoxy-D-xylulose-5-phosphate synthase - Novosphingobium|
            aromaticivorans (strain DSM 12444)
          Length = 640

 Score = 33.5 bits (75), Expect = 3.0
 Identities = 34/130 (26%), Positives = 53/130 (40%), Gaps = 5/130 (3%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + K+  +    I   GDG  S G  + A+N A  A   +I    +N  
Sbjct: 123  STSISAALGFAIANKLSGRLGKGIAVIGDGAMSAGMAYEAMNNAEAAGNRLIVILNDNDM 182

Query: 1111 AISTPTAE-QFRSDGVVTRGQAYGIRSI--RLDGNDTLAVYSAVHTAREMA--ITEGRPI 1275
            +I+ P          +V+ G   G+R I  RL       ++ A     E A  +  G  +
Sbjct: 183  SIAPPVGGLSAYLARLVSSGPFLGLRDIARRLSRKLPRPLHEAARKTDEFARGMAMGGTL 242

Query: 1276 LIEAMTYRVG 1305
              E   Y VG
Sbjct: 243  FEELGFYYVG 252

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>Q3ZXC2:DXS_DEHSC 1-deoxy-D-xylulose-5-phosphate synthase - Dehalococcoides sp. (strain|
            CBDB1)
          Length = 647

 Score = 33.5 bits (75), Expect = 3.0
 Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 10/113 (8%)
 Frame = +1

Query: 820  EFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTV--SSP--------IATQLPQAVGAAYS 969
            +  +Q + +KL  G+  Q         L+ FT    SP         +T +   +G A +
Sbjct: 85   DVGHQSYAHKLLTGRREQFATLRQHGGLSGFTCRDESPHDPFGAGHASTSISAGLGMAVA 144

Query: 970  LKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
              + K+    I+  GDG  S G    A+N A       I    +NG AIS  T
Sbjct: 145  RDLAKEDYSVISVIGDGAISGGMSFEAINNAGHLHTKFIVILNDNGMAISPST 197

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>Q3Z8G9:DXS_DEHE1 1-deoxy-D-xylulose-5-phosphate synthase - Dehalococcoides ethenogenes|
            (strain 195)
          Length = 647

 Score = 33.5 bits (75), Expect = 3.0
 Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 10/113 (8%)
 Frame = +1

Query: 820  EFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTV--SSP--------IATQLPQAVGAAYS 969
            +  +Q + +KL  G+  Q         L+ FT    SP         +T +   +G A +
Sbjct: 85   DVGHQSYAHKLLTGRREQFATLRQHGGLSGFTCRDESPHDPFGAGHASTSISAGLGMAVA 144

Query: 970  LKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPT 1128
              + K+    I+  GDG  S G    A+N A       I    +NG AIS  T
Sbjct: 145  RDLAKEDYSVISVIGDGAISGGMSFEAINNAGHLHTKFIVILNDNGMAISPST 197

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>Q13RX1:DXS_BURXL 1-deoxy-D-xylulose-5-phosphate synthase - Burkholderia xenovorans|
            (strain LB400)
          Length = 635

 Score = 33.5 bits (75), Expect = 3.0
 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVA-EAPMIFFCRNNG 1107
            +T +  A+G A + K+       I   GDG  + G    A+N A V  + P++    +N 
Sbjct: 118  STSISAALGMAVASKLKGDNRMGIAVIGDGAMTAGMAFEAMNNAGVEDDVPLLVILNDND 177

Query: 1108 WAISTPTAEQFRSDGVVTRGQAY 1176
             +IS P     R    +  G+ Y
Sbjct: 178  MSISPPVGALNRHLARLMSGRFY 200

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>Q9H0I9:TKTL2_HUMAN Transketolase-like protein 2 - Homo sapiens (Human)|
          Length = 626

 Score = 33.1 bits (74), Expect = 3.9
 Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 2/122 (1%)
 Frame = +1

Query: 940  LPQAVGAAYSLK-MDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAP-MIFFCRNNGWA 1113
            L  A G AY+ K +DK         GDG +SEG    A  FA+      ++     N   
Sbjct: 130  LGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLVAVFDVNRLG 189

Query: 1114 ISTPTAEQFRSDGVVTRGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEGRPILIEAMT 1293
             S P   +  +D      +A+G  +  +DG+D  A+  A   A ++   + +P  I A T
Sbjct: 190  QSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQV---KNKPTAIVAKT 246

Query: 1294 YR 1299
            ++
Sbjct: 247  FK 248

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>Q88QG7:DXS_PSEPK 1-deoxy-D-xylulose-5-phosphate synthase - Pseudomonas putida (strain|
            KT2440)
          Length = 631

 Score = 33.1 bits (74), Expect = 3.9
 Identities = 18/63 (28%), Positives = 29/63 (46%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + ++      +I   GDG  + G    ALN A    A M+    +N  
Sbjct: 131  STSISAALGMAIAARLQNSARKSIAVIGDGALTAGMAFEALNHAQEVNADMLVILNDNDM 190

Query: 1111 AIS 1119
            +IS
Sbjct: 191  SIS 193

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>Q8CJ78:ZN628_MOUSE Zinc finger protein 628 - Mus musculus (Mouse)|
          Length = 1031

 Score = 32.7 bits (73), Expect = 5.1
 Identities = 27/110 (24%), Positives = 40/110 (36%), Gaps = 1/110 (0%)
 Frame = -3

Query: 556 RRQEHGNS*SFPFAT-LAGNSFHQQRKAFLQGNLHTADRLRQVHSPVPXXXXXXXXXXXX 380
           RR  H ++   P+   + G SF Q         +HT +R      P+             
Sbjct: 155 RRHRHVHTGERPYTCGICGKSFTQSTNLRQHQRVHTGER--PFRCPLCPKTFTHSSNLLL 212

Query: 379 XXXXRTPCFGPLLAPREPGLSTSSRTTALVHDRAARQRPSWQPGVPTTRP 230
                 P  GP  AP  PG ++ + T  LV D   + R   +P  P  +P
Sbjct: 213 HHRTHGPAPGPAPAPAPPGETSRADTKVLVSDAYLQPRSPPEPPAPPPQP 262

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>Q8CGF7:TCRG1_MOUSE Transcription elongation regulator 1 - Mus musculus (Mouse)|
          Length = 1100

 Score = 32.7 bits (73), Expect = 5.1
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
 Frame = -1

Query: 1515 PVFWHPLGHLNGLQELLPHIVPELRLLSTAPPSIPLNPFSVPGDGIPCCSP---MLHLIS 1345
            PV   P  H   L   +PH VP+      A P + + PF VP  G+P   P   M+ ++S
Sbjct: 330  PVQTVPQPHPQTLPPAVPHSVPQPAAAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVS 389

Query: 1344 RP 1339
             P
Sbjct: 390  CP 391

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>O14776:TCRG1_HUMAN Transcription elongation regulator 1 - Homo sapiens (Human)|
          Length = 1098

 Score = 32.7 bits (73), Expect = 5.1
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
 Frame = -1

Query: 1515 PVFWHPLGHLNGLQELLPHIVPELRLLSTAPPSIPLNPFSVPGDGIPCCSP---MLHLIS 1345
            PV   P  H   L   +PH VP+      A P + + PF VP  G+P   P   M+ ++S
Sbjct: 328  PVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVS 387

Query: 1344 RP 1339
             P
Sbjct: 388  CP 389

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>Q02137:ILVB_LACLA Acetolactate synthase large subunit - Lactococcus lactis subsp.|
            lactis (Streptococcus lactis)
          Length = 575

 Score = 32.7 bits (73), Expect = 5.1
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 11/134 (8%)
 Frame = +1

Query: 940  LPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAIS 1119
            +P A+GA    K+ +     I + GDGG    +   AL       A  +    N+   + 
Sbjct: 425  IPAAIGA----KLAQPNKNVIVFVGDGGFQMTNQELAL-LNGYGIAIKVVLINNHSLGMV 479

Query: 1120 TPTAEQF----RSDGVVT-------RGQAYGIRSIRLDGNDTLAVYSAVHTAREMAITEG 1266
                E F    RS  V           +AYGI+ ++LD   TLA    +       ITE 
Sbjct: 480  RQWQESFYEERRSQSVFDVEPNFQLLAEAYGIKHVKLDNPKTLADDLKI-------ITED 532

Query: 1267 RPILIEAMTYRVGH 1308
             P+LIE +  +  H
Sbjct: 533  EPMLIEVLISKSEH 546

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>Q24V05:DXS_DESHY 1-deoxy-D-xylulose-5-phosphate synthase - Desulfitobacterium|
            hafniense (strain Y51)
          Length = 631

 Score = 32.7 bits (73), Expect = 5.1
 Identities = 20/63 (31%), Positives = 30/63 (47%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  AVG A +  + K+K   +   GDG  + G    ALN A   +  MI    +N  
Sbjct: 117  STSISAAVGFAKARDLRKEKNQVVAVIGDGAMTGGMAFEALNHAGHTKTNMIVVLNDNEM 176

Query: 1111 AIS 1119
            AI+
Sbjct: 177  AIA 179

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>Q2RR29:DXS2_RHORT 1-deoxy-D-xylulose-5-phosphate synthase 2 - Rhodospirillum rubrum|
            (strain ATCC 11170 / NCIB 8255)
          Length = 645

 Score = 32.7 bits (73), Expect = 5.1
 Identities = 22/69 (31%), Positives = 36/69 (52%)
 Frame = +1

Query: 919  SSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCR 1098
            S+ I+  L  A+G+A  L  D +   A+   GDG  S G  + A+N A  A++ +I    
Sbjct: 123  STSISAGLGMAIGSA--LAGDARDVVAV--IGDGSMSAGMAYEAMNNAGAAKSRLIVILN 178

Query: 1099 NNGWAISTP 1125
            +N  +I+ P
Sbjct: 179  DNDMSIAPP 187

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>Q2RYD6:DXS1_RHORT 1-deoxy-D-xylulose-5-phosphate synthase 1 - Rhodospirillum rubrum|
            (strain ATCC 11170 / NCIB 8255)
          Length = 645

 Score = 32.7 bits (73), Expect = 5.1
 Identities = 22/69 (31%), Positives = 36/69 (52%)
 Frame = +1

Query: 919  SSPIATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCR 1098
            S+ I+  L  A+G+A  L  D +   A+   GDG  S G  + A+N A  A++ +I    
Sbjct: 123  STSISAGLGMAIGSA--LAGDARDVVAV--IGDGSMSAGMAYEAMNNAGAAKSRLIVILN 178

Query: 1099 NNGWAISTP 1125
            +N  +I+ P
Sbjct: 179  DNDMSIAPP 187

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>P63984:DPO3_STRA5 DNA polymerase III polC-type - Streptococcus agalactiae serotype V|
          Length = 1468

 Score = 32.7 bits (73), Expect = 5.1
 Identities = 22/99 (22%), Positives = 39/99 (39%)
 Frame = +1

Query: 1231 VHTAREMAITEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQ 1410
            V T     + EG    +E  T R G H  +   T Y  +  M+ W    + + +Y    +
Sbjct: 240  VTTEENRIVFEGMVFSVERKTTRTGRHIINFKMTDYTSSFAMQKWAKDDEELKKYDMISK 299

Query: 1411 GNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAEL 1527
            G+  W   + +   NN  + L   +Q  + +  H   +L
Sbjct: 300  GS--WLRVRGNIENNNFTKSLTMNVQDIKEIVHHERKDL 336

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>P63983:DPO3_STRA3 DNA polymerase III polC-type - Streptococcus agalactiae serotype III|
          Length = 1468

 Score = 32.7 bits (73), Expect = 5.1
 Identities = 22/99 (22%), Positives = 39/99 (39%)
 Frame = +1

Query: 1231 VHTAREMAITEGRPILIEAMTYRVGHHSTSDDSTKYRPADEMEHWRTARDPVSRYRKWVQ 1410
            V T     + EG    +E  T R G H  +   T Y  +  M+ W    + + +Y    +
Sbjct: 240  VTTEENRIVFEGMVFSVERKTTRTGRHIINFKMTDYTSSFAMQKWAKDDEELKKYDMISK 299

Query: 1411 GNGWWCGTQESQLRNNVRQELLQAIQVAERMPKHGLAEL 1527
            G+  W   + +   NN  + L   +Q  + +  H   +L
Sbjct: 300  GS--WLRVRGNIENNNFTKSLTMNVQDIKEIVHHERKDL 336

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>Q87RU0:DXS_VIBPA 1-deoxy-D-xylulose-5-phosphate synthase - Vibrio parahaemolyticus|
          Length = 621

 Score = 32.3 bits (72), Expect = 6.6
 Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 10/143 (6%)
 Frame = +1

Query: 820  EFANQLFGNKLDYGKGRQMPIHYGSNRLN---------YFTVS-SPIATQLPQAVGAAYS 969
            +  +Q + +K+  G+  QMP     + L+         Y T+S    +T +   +G A S
Sbjct: 77   DVGHQAYPHKILTGRRDQMPTIRQKDGLHPFPWREESEYDTLSVGHSSTSISAGLGLAIS 136

Query: 970  LKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFRSD 1149
             + + K    I+  GDG  + G    A+N A      M+    +N  +IS          
Sbjct: 137  AQKEGKGRKVISVIGDGAITAGMAFEAMNHAGDVHPDMLVILNDNEMSISENVGALNNHL 196

Query: 1150 GVVTRGQAYGIRSIRLDGNDTLA 1218
              V  G  Y   SIR  G   L+
Sbjct: 197  AKVLSGSLY--TSIREGGKKVLS 217

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>Q474C2:DXS_RALEJ 1-deoxy-D-xylulose-5-phosphate synthase - Ralstonia eutropha (strain|
            JMP134) (Alcaligenes eutrophus)
          Length = 638

 Score = 32.3 bits (72), Expect = 6.6
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAV-AEAPMIFFCRNNG 1107
            +T +  A+G A   +   ++  +I   GDG  + G    ALN A V  + P++    +N 
Sbjct: 119  STSISAALGMALGARTLGEQRVSIAVIGDGAMTAGMAFEALNNAGVYKDLPLVVVLNDND 178

Query: 1108 WAISTPTAEQFRSDGVVTRGQAY 1176
             +IS P     +    +  GQ Y
Sbjct: 179  MSISPPVGALNKHLARLLSGQFY 201

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>Q4ZYU8:DXS_PSEU2 1-deoxy-D-xylulose-5-phosphate synthase - Pseudomonas syringae pv.|
            syringae (strain B728a)
          Length = 630

 Score = 32.3 bits (72), Expect = 6.6
 Identities = 18/63 (28%), Positives = 30/63 (47%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + ++   +  +I   GDG  + G    ALN A    A M+    +N  
Sbjct: 131  STSISAALGMAIASRLQGSERKSIAVIGDGALTAGMAFEALNHAPEVAADMLVILNDNDM 190

Query: 1111 AIS 1119
            +IS
Sbjct: 191  SIS 193

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>Q2W367:DXS_MAGMM 1-deoxy-D-xylulose-5-phosphate synthase - Magnetospirillum magneticum|
            (strain AMB-1 / ATCC 700264)
          Length = 644

 Score = 32.3 bits (72), Expect = 6.6
 Identities = 18/65 (27%), Positives = 30/65 (46%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A +  +       I   GDG  S G  + A+N A  A + +I    +N  
Sbjct: 128  STSISAALGMAVARDLKGATNNVIAVIGDGAMSAGQAYEAMNNAGAAGSRLIVILNDNDM 187

Query: 1111 AISTP 1125
            +I+ P
Sbjct: 188  SIAPP 192

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>O78328:DXS_CAPAN Probable 1-deoxy-D-xylulose-5-phosphate synthase, chloroplast|
            precursor - Capsicum annuum (Bell pepper)
          Length = 719

 Score = 32.3 bits (72), Expect = 6.6
 Identities = 36/144 (25%), Positives = 56/144 (38%), Gaps = 10/144 (6%)
 Frame = +1

Query: 814  LQEFANQLFGNKLDYGKGRQMPIHYGSNRLNYFTVSSPI----------ATQLPQAVGAA 963
            L +  +Q + +K+  G+  +M     +N L  FT  S            +T +   +G A
Sbjct: 140  LWDVGHQSYPHKILTGRREKMSTLRQTNGLAGFTKRSESEYDCFGTGHSSTTISAGLGMA 199

Query: 964  YSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFR 1143
                +  +    I   GDG  + G  + A+N A   ++ MI    +N   +S PTA    
Sbjct: 200  VGRDLKGRNNNVIAVIGDGAMTAGQAYEAMNNAGYLDSDMIVILNDNR-QVSLPTA---T 255

Query: 1144 SDGVVTRGQAYGIRSIRLDGNDTL 1215
             DG V    A      RL  N  L
Sbjct: 256  LDGPVPPVGALSSALSRLQSNRPL 279

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>Q1BLY7:DXS_BURCA 1-deoxy-D-xylulose-5-phosphate synthase - Burkholderia cenocepacia|
            (strain AU 1054)
          Length = 634

 Score = 32.3 bits (72), Expect = 6.6
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAE-APMIFFCRNNG 1107
            +T +  A+G A   +++     +I   GDG  + G    A+N A V+E A ++    +N 
Sbjct: 118  STSISAALGMAIGSQLNGDDRFSIAVIGDGAMTAGMAFEAMNNAGVSEDAKLLVILNDND 177

Query: 1108 WAISTPTAEQFRSDGVVTRGQAY 1176
             +IS P     R    +  G+ Y
Sbjct: 178  MSISPPVGALNRHLARLMSGRFY 200

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>Q6D1S9:RECX_ERWCT Regulatory protein recX - Erwinia carotovora subsp. atroseptica|
            (Pectobacterium atrosepticum)
          Length = 162

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 23/79 (29%), Positives = 36/79 (45%)
 Frame = +1

Query: 964  YSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGWAISTPTAEQFR 1143
            YS    ++K  A  Y  +G  SE D   A   A   EA  I +C+ +GW      A ++ 
Sbjct: 17   YSEVEIRRKCAAYLYKSEGTESEADEAIAQATAEDVEAA-IAYCKEHGWLDDARYARRYI 75

Query: 1144 SDGVVTRGQAYGIRSIRLD 1200
            S       + YG++ IR++
Sbjct: 76   SS---RSRKGYGVQRIRME 91

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>Q6L126:RADA_PICTO DNA repair and recombination protein radA - Picrophilus torridus|
          Length = 323

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 18/101 (17%)
 Frame = -1

Query: 660 EYCVHNLEGDHVTVHFQSQVLA----------------DLLESTVVYSATIVVKNTVTVD 529
           EY +  L  D +T HF+S+ +                 DLL+   +Y+A I V N V+ +
Sbjct: 200 EYKIRLLIVDSLTSHFRSEYVGRGSLAERQQLLNRHMHDLLKFGTIYNAVIAVTNQVSAN 259

Query: 528 P--FRLRLWQEIHFTNKGKLSSREIYTLQTACGKSILRFLD 412
           P  F       I     G  ++  IY  +   GK I R +D
Sbjct: 260 PAVFFGDPMNPIGGNIVGHTATFRIYLRKAKAGKRIARLID 300

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>P49057:GUAA_SYNY3 GMP synthase [glutamine-hydrolyzing] - Synechocystis sp. (strain PCC|
            6803)
          Length = 542

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
 Frame = -1

Query: 1473 ELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCRVMAD 1300
            E+L +     +L    P  I L+  P SV   G P C P +  +  PVLG   G ++M  
Sbjct: 54   EVLSYRTTAQQLREIKPKGIILSGGPNSVYDQGAPECDPEIFQLGVPVLGVCYGMQLMVK 113

Query: 1299 SVGHRLD 1279
             +G R++
Sbjct: 114  QLGGRVE 120

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>Q6AD51:GUAA_LEIXX GMP synthase [glutamine-hydrolyzing] - Leifsonia xyli subsp. xyli|
          Length = 503

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
 Frame = -1

Query: 1485 NGLQELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCR 1312
            N   E++PH V    + +  P  I L+  P SV  +G P     +  +  PVLG   G +
Sbjct: 5    NVYSEIVPHTVTAADIAAKRPAGIILSGGPSSVYEEGAPRLDEGIFELGVPVLGICYGFQ 64

Query: 1311 VMADSVG 1291
            VMA ++G
Sbjct: 65   VMAVALG 71

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>Q9KF78:GUAA_BACHD Putative GMP synthase [glutamine-hydrolyzing] - Bacillus halodurans|
          Length = 513

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
 Frame = -1

Query: 1473 ELLPHIVPELRLLSTAPPSIPLN--PFSVPGDGIPCCSPMLHLISRPVLG*IVGCRVMAD 1300
            EL P+ +   +L    P  I  +  P S   +G P C P +  +  P+LG   G ++M  
Sbjct: 34   ELHPNTITAEQLKEMKPKGIIFSGGPNSAYAEGAPKCDPAIFDLGVPILGICYGMQLMTQ 93

Query: 1299 SVGHRLD 1279
              G ++D
Sbjct: 94   HFGGKVD 100

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>Q889Q1:DXS_PSESM 1-deoxy-D-xylulose-5-phosphate synthase - Pseudomonas syringae pv.|
            tomato
          Length = 631

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 18/63 (28%), Positives = 30/63 (47%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + ++   +  +I   GDG  + G    ALN A    A M+    +N  
Sbjct: 131  STSISAALGMAIASRLQGSERKSIAVIGDGALTAGMAFEALNHAPEVAANMLVILNDNDM 190

Query: 1111 AIS 1119
            +IS
Sbjct: 191  SIS 193

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>Q48NX0:DXS_PSE14 1-deoxy-D-xylulose-5-phosphate synthase - Pseudomonas syringae pv.|
            phaseolicola (strain 1448A / Race 6)
          Length = 630

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 18/63 (28%), Positives = 30/63 (47%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + ++   +  +I   GDG  + G    ALN A    A M+    +N  
Sbjct: 131  STSISAALGMAIASRLQGSERKSIAVIGDGALTAGMAFEALNHAPEVAANMLVILNDNDM 190

Query: 1111 AIS 1119
            +IS
Sbjct: 191  SIS 193

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>Q1QQ40:DXS_NITHX 1-deoxy-D-xylulose-5-phosphate synthase - Nitrobacter hamburgensis|
            (strain X14 / DSM 10229)
          Length = 668

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 22/88 (25%), Positives = 38/88 (43%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  ++G A +  +   K   I   GDG  S G  + A+N A    + +I    +N  
Sbjct: 149  STSISASLGMAVARDLSGGKNNVIAVIGDGAMSAGMAYEAMNNAGAMNSRLIVILNDNDM 208

Query: 1111 AISTPTAEQFRSDGVVTRGQAYGIRSIR 1194
            +I+ P          +  G+ Y  RS+R
Sbjct: 209  SIAPPVGAMSAYLSRLYSGKTY--RSLR 234

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>Q487D3:DXS_COLP3 1-deoxy-D-xylulose-5-phosphate synthase - Colwellia psychrerythraea|
            (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
          Length = 630

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 17/63 (26%), Positives = 29/63 (46%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAEAPMIFFCRNNGW 1110
            +T +  A+G A + + + K    +   GDG  + G    ALN A   +  M+    +N  
Sbjct: 124  STSISAALGLAVAAEKEAKNRKTVAVIGDGAMTAGMAFEALNHAGDIKKDMLIILNDNDM 183

Query: 1111 AIS 1119
            +IS
Sbjct: 184  SIS 186

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>Q393P4:DXS_BURS3 1-deoxy-D-xylulose-5-phosphate synthase - Burkholderia sp. (strain|
            383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086
            / R18194))
          Length = 634

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +1

Query: 931  ATQLPQAVGAAYSLKMDKKKACAITYFGDGGTSEGDFHAALNFAAVAE-APMIFFCRNNG 1107
            +T +  A+G A   +++     +I   GDG  + G    A+N A V+E A ++    +N 
Sbjct: 118  STSISAALGMAIGSQLNGDDRFSIAVIGDGAMTAGMAFEAMNNAGVSEDAKVLVILNDND 177

Query: 1108 WAISTPTAEQFRSDGVVTRGQAY 1176
             +IS P     R    +  G+ Y
Sbjct: 178  MSISPPVGALNRHLARLMSGRFY 200


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 337,896,744
Number of extensions: 8048805
Number of successful extensions: 23495
Number of sequences better than 10.0: 152
Number of HSP's gapped: 23408
Number of HSP's successfully gapped: 152
Length of query: 597
Length of database: 100,686,439
Length adjustment: 119
Effective length of query: 478
Effective length of database: 68,045,334
Effective search space: 32525669652
Effective search space used: 32525669652
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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full-length cDNA and EST

Clone Information

BLAST Search Result