ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf27n13 |
|---|---|
| Clone Library Name | barley_pub |
>O75716:STK16_HUMAN Serine/threonine-protein kinase 16 - Homo sapiens (Human)| Length = 305 Score = 185 bits (469), Expect = 4e-46 Identities = 111/313 (35%), Positives = 171/313 (54%) Frame = +1 Query: 160 GDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQS 339 G V I+ +R+ ++++GEGGF++V LV+ H H YA+K++L Sbjct: 11 GTVIIDNKRYLFIQKLGEGGFSYVDLVE----------GLHDGHF-----YALKRILCHE 55 Query: 340 REQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNA 519 ++ + + E + LFNHPN+L L+ + + + HEA+LL P GTL++ Sbjct: 56 QQDREEAQREADMHRLFNHPNILRLVAYCL-----RERGAKHEAWLLLPFFKRGTLWNEI 110 Query: 520 AVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATL 699 ++ + F + +L + IC GL+ +H+ YAH D+KP N+L+ G L Sbjct: 111 ERLKDKGNFLTEDQILWLLLGICRGLEAIHAKG--YAHRDLKPTNILL----GDEGQPVL 164 Query: 700 MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCT 879 MD GS A + +AL LQ+WAA+ C+ +RAPEL+ SH IDERTD+WSLGC Sbjct: 165 MDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCV 224 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 LYA+M+G P++ + G S+ LA+ N QL PQ SP + AL + + M+ P R Sbjct: 225 LYAMMFGEGPYDMVF-QKGDSVALAVQN-QLSIPQ--SPRHSSALRQLLNSMMTVDPHQR 280 Query: 1060 PHINDILLHVDKL 1098 PHI +L ++ L Sbjct: 281 PHIPLLLSQLEAL 293
>P57760:STK16_RAT Serine/threonine-protein kinase 16 - Rattus norvegicus (Rat)| Length = 305 Score = 184 bits (466), Expect = 1e-45 Identities = 110/313 (35%), Positives = 171/313 (54%) Frame = +1 Query: 160 GDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQS 339 G V I+ +R+ ++++GEGGF++V LV+ H H YA+K++L Sbjct: 11 GTVIIDNKRYLFVQKLGEGGFSYVDLVE----------GLHDGHF-----YALKRILCHE 55 Query: 340 REQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNA 519 ++ + + E + LF HPN+L L+ +++ + HEA+LL P GTL++ Sbjct: 56 QQDQEEAQREADMHRLFQHPNILRLMAYSL-----KERGAKHEAWLLLPFFKRGTLWNEI 110 Query: 520 AVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATL 699 ++ + F + +L + IC GL+ +H+ YAH D+KP N+L+ G L Sbjct: 111 ERLKDQGNFLTEDQILPLLLGICRGLEAIHAKG--YAHRDLKPTNILL----GDEGQPVL 164 Query: 700 MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCT 879 MD GS A Q+ +AL LQ+WAA+ C+ +RAPEL+ SH IDERTD+WSLGC Sbjct: 165 MDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCV 224 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 LYA+M+G P++ + G S+ LA+ N L PQ SP + AL + + M+ P R Sbjct: 225 LYAMMFGEGPYDMVF-QKGDSVALAVQN-DLSIPQ--SPRHSSALRQLLASMMTVDPQQR 280 Query: 1060 PHINDILLHVDKL 1098 PHI +L ++ L Sbjct: 281 PHIPVLLSQLEAL 293
>O88697:STK16_MOUSE Serine/threonine-protein kinase 16 - Mus musculus (Mouse)| Length = 305 Score = 182 bits (462), Expect = 3e-45 Identities = 109/313 (34%), Positives = 172/313 (54%) Frame = +1 Query: 160 GDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQS 339 G V I+ +R+ ++++GEGGF++V LV+ H H YA+K++L Sbjct: 11 GTVIIDNKRYLFVQKLGEGGFSYVDLVE----------GLHDGHF-----YALKRILCHE 55 Query: 340 REQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNA 519 ++ + + E + LF HPN+L L+ +++ + HEA+LL P GTL++ Sbjct: 56 QQDQEEAQREAEMHRLFQHPNILRLMAYSL-----KERGAKHEAWLLLPFFKKGTLWNEI 110 Query: 520 AVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATL 699 ++ + F + +L + I GL+ +H+ YAH D+KP N+L+ G L Sbjct: 111 ERLKDQGSFLTEDQILPLLLGISRGLEAIHAKG--YAHRDLKPTNILL----GDEGQPVL 164 Query: 700 MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCT 879 MD GS A Q+ +AL LQ+WAA+ C+ +RAPEL+ SH IDERTD+WSLGC Sbjct: 165 MDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCV 224 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 LYA+M+G P++ + G S+ LA+ N +L PQ SP + AL + ++ M+ P R Sbjct: 225 LYAMMFGEGPYDMVF-QKGDSVALAVQN-ELSIPQ--SPRHSSALRQLLSSMMTVDPQQR 280 Query: 1060 PHINDILLHVDKL 1098 PHI +L ++ L Sbjct: 281 PHIPVLLSQLEAL 293
>Q10078:PPK13_SCHPO Serine/threonine-protein kinase ppk13 - Schizosaccharomyces pombe| (Fission yeast) Length = 344 Score = 145 bits (366), Expect = 4e-34 Identities = 105/340 (30%), Positives = 156/340 (45%), Gaps = 31/340 (9%) Frame = +1 Query: 166 VWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ-SR 342 V IN R+R+ + +GEGGFAFVYLV+ +VS + YA+KK+ Sbjct: 25 VCINNERYRIQKLLGEGGFAFVYLVQ---------------NVSNEKLYALKKIKCSFGN 69 Query: 343 EQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAA 522 + + +E F LL H ++ + D S Y+LFP G++ Sbjct: 70 KGIKKAMKEADYHRKFKSNYLLKSYTHQLVK----EADGSEFVYILFPYFAKGSVAQVIR 125 Query: 523 VMQSRKEFYSVLDVLRIFQQICEGLKHMHS-----------------LDPP--------- 624 + S +L +C+ L+++H D P Sbjct: 126 NCDIEGSYISEKRILVWCSCLCKALQYLHENVAGDSPKQPEVNDLIMFDEPQVPQNTSNN 185 Query: 625 ----YAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCS 792 Y H D+KP N+L+ + L DFGS + SEA+ +Q+ A+E+C+ Sbjct: 186 NLVSYIHGDIKPDNLLLHENSREI---VLTDFGSICLVPIFASNNSEAIAIQDKASENCT 242 Query: 793 APFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQL 972 PFRAPEL+ + + I E+ DIWS GCTLY IM+ SPFE + + GGSL LA+ NAQ Sbjct: 243 MPFRAPELFHVKAGSTITEKADIWSFGCTLYTIMFHASPFEREVSQ-GGSLALAVCNAQY 301 Query: 973 KWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLHVD 1092 +P+ PY L + V LQ +P RP ++L +D Sbjct: 302 SFPR--KHPYSTLLCEIVEACLQREPNKRPSARELLSKID 339
>Q12003:KP236_YEAST Serine/threonine-protein kinase YPL236C - Saccharomyces cerevisiae| (Baker's yeast) Length = 364 Score = 124 bits (311), Expect = 9e-28 Identities = 92/347 (26%), Positives = 148/347 (42%), Gaps = 44/347 (12%) Frame = +1 Query: 172 INERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQL 351 +N++R+R+ R +GEGG +FVYLV+ S + ++ YA+KK++ S E + Sbjct: 25 VNDKRYRIQRLLGEGGMSFVYLVQLSKNSLII-----DNGIATPELYALKKIICPSVESI 79 Query: 352 DLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQ 531 EI F P ++ +D ++ K D S Y++ P + G+L D+ Sbjct: 80 SNGMREIENYKRFQSPYVIKSIDSQVMQEK----DGSKTIYIVLPYYSLGSLQDSINRRL 135 Query: 532 SRKEFYSVLDVLRIFQQICEGLKHMHSL-----------------------------DPP 624 F S + +RI + GL +H D P Sbjct: 136 LEGTFVSEAECVRIMLGVTRGLLCLHDPASRQDNATSRVNVDAVSMTYSDETAMLLEDTP 195 Query: 625 ---------------YAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEAL 759 YAH D+ P N+L + L + D GS A I +R + Sbjct: 196 LEMDMLSSNSAGSIAYAHRDITPSNILFSSDG----LPVIGDLGSCSQADITIENRHQLS 251 Query: 760 RLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGG 939 LQEW ++C+ P+ PEL + + + + DIWSLGCT Y +M+G+SPFE G Sbjct: 252 ELQEWVNDNCTLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGA 311 Query: 940 SLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 SL AI + +P+ + + + L + +Q P RP + +L Sbjct: 312 SLTYAINTGKYSFPR--NSRFSEGLLSVIKKCIQVDPIQRPTTSQLL 356
>O43066:PPK30_SCHPO Serine/threonine-protein kinase ppk30 - Schizosaccharomyces pombe| (Fission yeast) Length = 953 Score = 119 bits (298), Expect = 3e-26 Identities = 88/320 (27%), Positives = 145/320 (45%), Gaps = 2/320 (0%) Frame = +1 Query: 136 LYDAATGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYA 315 L+ G + + + R + EGGF+ VYL + + + Sbjct: 40 LFSKIPAGTKIQVGSHSVIIQRYLSEGGFSHVYLAL----------------LENEKPFV 83 Query: 316 MKKVLIQSREQLDLVKEEIR-VSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVH 492 +K++ + + L LV EI + L H +++ +D + + KS +E YLL Sbjct: 84 LKRIYVPDKTALQLVHGEIETMKRLKGHRHIVNYIDSSALYSKSEN---RYEVYLLMEFC 140 Query: 493 LDGTLFDNAAVMQSRKEF-YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTR 669 G L D M +R + + ++L+I +C+ + MH LDPP H D+K NVL+ Sbjct: 141 AGGGLID---FMNTRLQHRLTEGEILKILADVCDAVAAMHYLDPPLIHRDLKIENVLLVA 197 Query: 670 QKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDE 849 L DFGS+ + + L++ A + + +RAPE+ D IDE Sbjct: 198 PNSYK----LCDFGSACEPLAPATTPDTIMFLEQNIAAYTTPQYRAPEMIDINRRQGIDE 253 Query: 850 RTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVT 1029 ++DIW++G Y + Y +PFE +G S AI+ A +P P P Y D + +F+ Sbjct: 254 KSDIWAIGVLAYKLCYYTTPFE-QVGNS------AILKASFSFP--PFPRYSDRMKRFIA 304 Query: 1030 WMLQPQPAMRPHINDILLHV 1089 LQ QP+ RP+I L + Sbjct: 305 TCLQEQPSHRPNIYQTLKEI 324
>P40494:PRK1_YEAST Actin-regulating kinase PRK1 - Saccharomyces cerevisiae (Baker's| yeast) Length = 810 Score = 117 bits (293), Expect = 1e-25 Identities = 90/318 (28%), Positives = 150/318 (47%), Gaps = 3/318 (0%) Frame = +1 Query: 172 INERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQL 351 + ++++ + GGFA VY A P S +K+V++ ++ L Sbjct: 17 VGSHHAKIIKYLTSGGFAQVY----------TAEISPPDPYSNANIACLKRVIVPHKQGL 66 Query: 352 DLVKEEIRVSSLF-NHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD--NAA 522 + ++ E+ L N+ +++ +D A +S G ++E ++L G L D N Sbjct: 67 NTLRAEVDAMKLLRNNKHVVSYIDSH--AARSVNGI-AYEVFVLMEFCERGGLIDFMNTR 123 Query: 523 VMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLM 702 + +E ++L I Q +G+ MH+L PP H D+K NVL++ L + Sbjct: 124 LQNRLQES----EILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDG----LYKVC 175 Query: 703 DFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTL 882 DFGS R+ E +Q + +A +R+PE+ D IDE++DIW+LG L Sbjct: 176 DFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFL 235 Query: 883 YAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRP 1062 Y I Y +PFE + GE+G I++A+ ++P P Y D L + ML P+ RP Sbjct: 236 YKICYYTTPFEKS-GEAG------ILHARYQYPSFPQ--YSDRLKNLIRLMLMEAPSQRP 286 Query: 1063 HINDILLHVDKLVEKYSP 1116 +I +L V +L K P Sbjct: 287 NICQVLEEVSRLQNKPCP 304
>Q9USS2:PPK29_SCHPO Serine/threonine-protein kinase ppk29 - Schizosaccharomyces pombe| (Fission yeast) Length = 872 Score = 117 bits (293), Expect = 1e-25 Identities = 91/315 (28%), Positives = 148/315 (46%), Gaps = 1/315 (0%) Frame = +1 Query: 157 GGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ 336 G I + + + I EGGF+ VYLV+ +++ D P T +K++ Sbjct: 15 GSKFVIGKYNVTIEKYIAEGGFSHVYLVQ-----TNSKTDGSPI------TAVLKRMYSP 63 Query: 337 SREQLDLVKEEIRVSSLF-NHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD 513 L VK EI L ++P+++ +D I ++ + E LL G L D Sbjct: 64 DENALRFVKTEIETMELLKSNPHVVSYIDSCIFPLEKAGVNTGFEILLLMEYCAGGGLID 123 Query: 514 NAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLA 693 + Q + S +VL+I I +G+ +H L PP H D+K NVL++ + Sbjct: 124 --FMNQRLQTRLSEHEVLKIISDIVQGVASLHYLRPPLIHRDLKVENVLLSFNTFK---- 177 Query: 694 TLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLG 873 L DFGS + + SE L++ + +RAPE+ + S IDE++D+W+LG Sbjct: 178 -LCDFGSVTEPMHAAENSSEIQALEKSINTFTTYQYRAPEMINLYSGLGIDEKSDMWALG 236 Query: 874 CTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPA 1053 LY + Y +PFE G + AI+ A +P P PPY +L + +LQP P Sbjct: 237 VLLYKLCYYTTPFE-TQGPN------AILTASYSFP--PFPPYSHSLKNVIIALLQPNPC 287 Query: 1054 MRPHINDILLHVDKL 1098 +RP+I ++ + +L Sbjct: 288 LRPNIFQLMCEICRL 302
>O14976:GAK_HUMAN Cyclin G-associated kinase - Homo sapiens (Human)| Length = 1311 Score = 115 bits (287), Expect = 5e-25 Identities = 94/332 (28%), Positives = 146/332 (43%), Gaps = 4/332 (1%) Frame = +1 Query: 115 SISGLNALYDAATGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHV 294 S+ G + + G V + E R RV R + EGGFAFVY ++ V Sbjct: 16 SLGGASGRDQSDFVGQTVELGELRLRVRRVLAEGGFAFVYEAQD---------------V 60 Query: 295 SGDGTYAMKKVLIQSREQLDLVKEEIR-VSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEA 471 YA+K++L E+ + +E+ + L HPN++ A I + + D Sbjct: 61 GSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKE--ESDTGQAE 118 Query: 472 YLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPG 651 +LL G L + M+SR S VL+IF Q C ++HMH PP H D+K Sbjct: 119 FLLLTELCKGQLVEFLKKMESRGPL-SCDTVLKIFYQTCRAVQHMHRQKPPIIHRDLKVE 177 Query: 652 NVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALR---LQEWAAEHCSAPFRAPELWD 822 N+L++ Q L DFGS+ + A R ++E + + +R PE+ D Sbjct: 178 NLLLSNQG----TIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEIID 233 Query: 823 CPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPY 1002 S+ I E+ DIW+LGC LY + + PFE +L I+N + P P Sbjct: 234 LYSNFPIGEKQDIWALGCILYLLCFRQHPFE-------DGAKLRIVNGKYSIP--PHDTQ 284 Query: 1003 PDALHKFVTWMLQPQPAMRPHINDILLHVDKL 1098 H + MLQ P R I +++ + ++ Sbjct: 285 YTVFHSLIRAMLQVNPEERLSIAEVVHQLQEI 316
>P53974:ARK1_YEAST Actin-regulating kinase 1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 638 Score = 110 bits (274), Expect = 2e-23 Identities = 84/314 (26%), Positives = 148/314 (47%), Gaps = 3/314 (0%) Frame = +1 Query: 157 GGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ 336 G + + + +++ + GGFA VY +A P S +K+V++ Sbjct: 12 GTQLTVGSHQVEIIKYLTSGGFAQVY----------SALINPPDPHSNSSVACLKRVIVP 61 Query: 337 SREQLDLVKEEIRVSSLF-NHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD 513 + L+ ++ E+ L N+ ++ +D A K+ + S+E ++L G L D Sbjct: 62 DKPSLNTLRAEVDAMRLLKNNRYVVSYIDSH--AAKAMLHNGSYEVFVLMEYCERGGLID 119 Query: 514 --NAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAP 687 N + EF ++L+I Q+ +G+ MH+L PP H D+K NVL++ Sbjct: 120 FMNTRLQNRLHEF----EILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYK- 174 Query: 688 LATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWS 867 L DFGS R+ E +Q+ ++ +A +R+PE+ D IDE++DIW+ Sbjct: 175 ---LCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWA 231 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 LG LY + Y +PF E GG LAI++ + ++P P+ Y + L + +L Sbjct: 232 LGIFLYKLCYYTTPF-----EKGG--DLAILSGKFEFPLYPN--YSEQLKGLIRDILVQD 282 Query: 1048 PAMRPHINDILLHV 1089 P RP++ +L + Sbjct: 283 PRHRPNVYQLLKRI 296
>P97874:GAK_RAT Cyclin G-associated kinase - Rattus norvegicus (Rat)| Length = 1305 Score = 104 bits (260), Expect = 7e-22 Identities = 84/318 (26%), Positives = 141/318 (44%), Gaps = 4/318 (1%) Frame = +1 Query: 157 GGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ 336 G V + E R RV R + EGGFAFVY ++ + + YA+K++L Sbjct: 30 GQTVELGELRLRVRRVLAEGGFAFVYEAQDLGSGRE---------------YALKRLLSN 74 Query: 337 SREQLDLVKEEIR-VSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD 513 E+ + +E+ + L HPN++ A I + + D +LL G L + Sbjct: 75 EEEKNRAIIQEVCFLKKLSGHPNIVQFCSAASIGKE--ESDTGQAEFLLLTELCKGQLVE 132 Query: 514 NAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLA 693 ++ + S +L+IF Q C ++HMH PP H D+K N+L++ Q Sbjct: 133 FLRRVECKGPL-SCDSILKIFYQTCRAVQHMHRQKPPIIHRDLKVENLLLSNQG----TI 187 Query: 694 TLMDFGSSRPARNQIR---SRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIW 864 L DFGS+ + S + ++E + + +R PE+ D S+ I E+ DIW Sbjct: 188 KLCDFGSATTISHYPDYSWSAQKRAMVEEEITRNTTPMYRTPEIVDLYSNFPIGEKQDIW 247 Query: 865 SLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQP 1044 +LGC LY + + PFE +L I+N + P + H + ML+ Sbjct: 248 ALGCILYLLCFRQHPFE-------DGAKLRIVNGKYSIP--VNDTRYTVFHDLIRGMLKV 298 Query: 1045 QPAMRPHINDILLHVDKL 1098 P R I +++ + ++ Sbjct: 299 NPEERLSIAEVVRQLQEI 316
>Q99KY4:GAK_MOUSE Cyclin G-associated kinase - Mus musculus (Mouse)| Length = 1305 Score = 104 bits (260), Expect = 7e-22 Identities = 84/318 (26%), Positives = 141/318 (44%), Gaps = 4/318 (1%) Frame = +1 Query: 157 GGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ 336 G V + E R RV R + EGGFAFVY ++ + + YA+K++L Sbjct: 30 GQTVELGELRLRVRRVLAEGGFAFVYEAQDLGSGRE---------------YALKRLLSN 74 Query: 337 SREQLDLVKEEIR-VSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD 513 E+ + +E+ + L HPN++ A I + + D +LL G L + Sbjct: 75 EEEKNRAIIQEVCFLKKLSGHPNIVQFCSAASIGKE--ESDTGQAEFLLLTELCKGQLVE 132 Query: 514 NAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLA 693 ++ + S +L+IF Q C ++HMH PP H D+K N+L++ Q Sbjct: 133 FLKRVECKGPL-SCDSILKIFYQTCRAVQHMHRQKPPIIHRDLKVENLLLSNQG----TI 187 Query: 694 TLMDFGSSRPARNQIR---SRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIW 864 L DFGS+ + S + ++E + + +R PE+ D S+ I E+ DIW Sbjct: 188 KLCDFGSATTISHYPDYSWSAQKRAMVEEEITRNTTPMYRTPEIVDLYSNFPIGEKQDIW 247 Query: 865 SLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQP 1044 +LGC LY + + PFE +L I+N + P + H + ML+ Sbjct: 248 ALGCILYLLCFRQHPFE-------DGAKLRIVNGKYSIP--VNDTRYTVFHDLIRAMLKV 298 Query: 1045 QPAMRPHINDILLHVDKL 1098 P R I +++ + ++ Sbjct: 299 NPVERLSIAEVVRQLQEI 316
>Q2M2I8:AAK1_HUMAN AP2-associated protein kinase 1 - Homo sapiens (Human)| Length = 863 Score = 104 bits (259), Expect = 1e-21 Identities = 95/340 (27%), Positives = 156/340 (45%), Gaps = 4/340 (1%) Frame = +1 Query: 109 GCSISGLNALYDAATGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPS 288 G S SGL + Y G I ++ V + EGGFA V+LV+ Sbjct: 24 GGSTSGLGSGYIGRVFG----IGRQQVTVDEVLAEGGFAIVFLVR--------------- 64 Query: 289 HVSGDGTYAMKKVLIQSREQLDLVKEEIRVS-SLFNHPNLLPLLDHAIIAVKSTQGD-WS 462 S A+K++ + + L + K EI++ L H N++ +D +I V S GD W Sbjct: 65 -TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSS--GDVW- 120 Query: 463 HEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDV 642 E +L G + + + Q + ++ +VL+IF CE + +H P H D+ Sbjct: 121 -EVLILMDFCRGGQVVN--LMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDL 177 Query: 643 KPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRS-RSEALR-LQEWAAEHCSAPFRAPEL 816 K N+L+ +G L DFGS A N+ ++ ++E + +++ ++ + +RAPE+ Sbjct: 178 KVENILL-HDRGHY---VLCDFGS---ATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEM 230 Query: 817 WDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSP 996 + S I + DIW+LGC LY + Y PF G Q+AI + P + Sbjct: 231 VNLYSGKIITTKADIWALGCLLYKLCYFTLPF--------GESQVAICDGNFTIPD--NS 280 Query: 997 PYPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP 1116 Y +H + +ML+P P RP I + KL++K P Sbjct: 281 RYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECP 320
>Q3UHJ0:AAK1_MOUSE AP2-associated protein kinase 1 - Mus musculus (Mouse)| Length = 959 Score = 103 bits (258), Expect = 1e-21 Identities = 95/340 (27%), Positives = 156/340 (45%), Gaps = 4/340 (1%) Frame = +1 Query: 109 GCSISGLNALYDAATGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPS 288 G S SGL + Y G I ++ V + EGGFA V+LV+ Sbjct: 24 GGSSSGLGSGYIGRVFG----IGRQQVTVDEVLAEGGFALVFLVR--------------- 64 Query: 289 HVSGDGTYAMKKVLIQSREQLDLVKEEIRVS-SLFNHPNLLPLLDHAIIAVKSTQGD-WS 462 S A+K++ + + L + K EI++ L H N++ +D +I V S GD W Sbjct: 65 -TSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSS--GDVW- 120 Query: 463 HEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDV 642 E +L G + + + Q + ++ +VL+IF CE + +H P H D+ Sbjct: 121 -EVLILMDFCRGGQVVN--LMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDL 177 Query: 643 KPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRS-RSEALR-LQEWAAEHCSAPFRAPEL 816 K N+L+ +G L DFGS A N+ ++ ++E + +++ ++ + +RAPE+ Sbjct: 178 KVENILL-HDRGHY---VLCDFGS---ATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEM 230 Query: 817 WDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSP 996 + S I + DIW+LGC LY + Y PF G Q+AI + P + Sbjct: 231 VNLYSGKIITTKADIWALGCLLYKLCYFTLPF--------GESQVAICDGSFTIPD--NS 280 Query: 997 PYPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP 1116 Y +H + +ML+P P RP I + KL++K P Sbjct: 281 RYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECP 320
>P38080:AKL1_YEAST Serine/threonine-protein kinase AKL1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1108 Score = 100 bits (250), Expect = 1e-20 Identities = 83/323 (25%), Positives = 145/323 (44%), Gaps = 1/323 (0%) Frame = +1 Query: 151 TGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVL 330 T G V + + V+ + EGGFA +Y+VK + ++ GD +K+VL Sbjct: 23 TPGHIVCVGTHKVEVVNYLAEGGFAQIYVVKFLEYLNEFDNTASVPLKIGD-VACLKRVL 81 Query: 331 IQSREQLDLVKEEIRV-SSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTL 507 +Q L+ ++ E+ V L PN++ D A + G E LL + + +L Sbjct: 82 VQDENGLNEMRNEVEVMKKLKGAPNIVQYFDSN--ASRRRDGVQGFEVLLLMELCPNKSL 139 Query: 508 FDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAP 687 D S K + ++++I + + MH L H D+K NVLV + Sbjct: 140 LDYMNQRLSTK--LTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNN--- 194 Query: 688 LATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWS 867 L DFGS+ + + + L + H + +R+PE+ D I+E++DIW+ Sbjct: 195 -FKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWA 253 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 LG LY +++ +PFE + Q AI++++ + P Y L + ML Sbjct: 254 LGVFLYKLLFFTTPFEM-------TGQFAILHSKY---EFPVNKYSSKLINLIIIMLAEN 303 Query: 1048 PAMRPHINDILLHVDKLVEKYSP 1116 P +RP+I +L H+ +++ P Sbjct: 304 PNLRPNIYQVLYHLCEILNVEVP 326
>P0C1X8:AAK1_RAT AP2-associated protein kinase 1 - Rattus norvegicus (Rat)| Length = 962 Score = 99.8 bits (247), Expect = 2e-20 Identities = 95/340 (27%), Positives = 156/340 (45%), Gaps = 4/340 (1%) Frame = +1 Query: 109 GCSISGLNALYDAATGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPS 288 G S SGL + Y G I ++ V + EGGFA V+LV+ Sbjct: 24 GGSSSGLGSGYIGRVFG----IGRQQVTVDEVLAEGGFALVFLVR--------------- 64 Query: 289 HVSGDGTYAMKKVLIQSREQLDLVKEEIRVS-SLFNHPNLLPLLDHAIIAVKSTQGD-WS 462 S A+K++ + + L + K EI++ L H N++ +D +I V S GD W Sbjct: 65 -TSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSS--GDVW- 120 Query: 463 HEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDV 642 E +L G + + + Q + ++ +VL+IF CE + +H P H D+ Sbjct: 121 -EVLILMDFCRGGQVVN--LMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDL 177 Query: 643 KPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRS-RSEALR-LQEWAAEHCSAPFRAPEL 816 K N+L+ +G L DFGS A N+ ++ ++E + +++ ++ + +RAPE+ Sbjct: 178 KVENILL-HDRGHY---VLCDFGS---ATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEM 230 Query: 817 WDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSP 996 + S I + DIW+LGC LY + Y PF G Q+AI + P + Sbjct: 231 VNLYSGKIITTKADIWALGCLLYKLCYFTLPF--------GESQVAICDGSFTIPD--NS 280 Query: 997 PYPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP 1116 Y +H + +ML+P P RP I + KL++K P Sbjct: 281 RYSQDMHCLI-YMLEPDPDKRPDIYQVSYFSFKLLKKECP 319
>Q91Z96:BMP2K_MOUSE BMP-2-inducible protein kinase - Mus musculus (Mouse)| Length = 1138 Score = 96.3 bits (238), Expect = 3e-19 Identities = 84/348 (24%), Positives = 152/348 (43%), Gaps = 3/348 (0%) Frame = +1 Query: 109 GCSISGLNALYDAATGGGDVW-INERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHP 285 G + GL + +++ G V+ + + + + EGGF+ V+LV+ H Sbjct: 21 GAAGGGLGGGFASSSMGVRVFAVGRYQVTLEESLAEGGFSTVFLVRTHSGIR-------- 72 Query: 286 SHVSGDGTYAMKKVLIQSREQLDLVKEEIRV-SSLFNHPNLLPLLDHAIIAVKSTQGDWS 462 A+K++ + + L++ K EI + L H N++ LD A+ ++ W Sbjct: 73 --------CALKRMYVNNTPDLNICKREITIMKELSGHKNIVGYLDCAVNSISDNV--W- 121 Query: 463 HEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDV 642 E +L G + + + + + ++ +VL+IF CE + +H P H D+ Sbjct: 122 -EVLILMEYCRAGQVVNQ--MNKKLQTGFTESEVLQIFCDTCEAVARLHQCKTPIIHRDL 178 Query: 643 KPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRL-QEWAAEHCSAPFRAPELW 819 K N+L+ A L DFGS+ + + + + + +E ++ + +RAPE+ Sbjct: 179 KVENILLN----DAGNYVLCDFGSA--TNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMI 232 Query: 820 DCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPP 999 + I + DIW+LGC LY + + PF G Q+AI + P + Sbjct: 233 NLYGGKPITTKADIWALGCLLYKLCFFTLPF--------GESQVAICDGSFTIPD--NSR 282 Query: 1000 YPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP*SQLAYSVL 1143 Y +H + +ML+P P RP I + K +K P S + S L Sbjct: 283 YSHNVHCLIRFMLEPDPECRPDIFQVSYFAFKFAKKDCPVSNINNSFL 330
>Q9NSY1:BMP2K_HUMAN BMP-2-inducible protein kinase - Homo sapiens (Human)| Length = 1161 Score = 94.4 bits (233), Expect = 1e-18 Identities = 84/337 (24%), Positives = 144/337 (42%), Gaps = 9/337 (2%) Frame = +1 Query: 145 AATGGGDVWINERRFRVLRQ-------IGEGGFAFVYLVKEHDASSDAARDRHPSHVSGD 303 A G G + R F V R + EGGF+ V+LV+ H G Sbjct: 30 AGCGSGGSSVGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTH----------------GG 73 Query: 304 GTYAMKKVLIQSREQLDLVKEEIRV-SSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLL 480 A+K++ + + L++ K EI + L H N++ LD A+ ++ W E +L Sbjct: 74 IRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISDNV--W--EVLIL 129 Query: 481 FPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVL 660 G + + + + + ++ +VL+IF CE + +H P H D+K N+L Sbjct: 130 MEYCRAGQVVNQ--MNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENIL 187 Query: 661 VTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRL-QEWAAEHCSAPFRAPELWDCPSHA 837 + L DFGS+ + + + + + +E ++ + +RAPE+ + Sbjct: 188 LNDGGNYV----LCDFGSA--TNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGK 241 Query: 838 DIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALH 1017 I + DIW+LGC LY + + PF G Q+AI + P + Y +H Sbjct: 242 PITTKADIWALGCLLYKLCFFTLPF--------GESQVAICDGNFTIPD--NSRYSRNIH 291 Query: 1018 KFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP*SQL 1128 + +ML+P P RP I + K +K P S + Sbjct: 292 CLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNI 328
>Q9UU85:PPK38_SCHPO Protein kinase domain-containing protein ppk38 - Schizosaccharomyces| pombe (Fission yeast) Length = 650 Score = 90.9 bits (224), Expect = 1e-17 Identities = 82/304 (26%), Positives = 127/304 (41%), Gaps = 2/304 (0%) Frame = +1 Query: 193 VLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEI 372 V R + EGGF+ VYLV+ + P +K++ L V EE+ Sbjct: 35 VKRYLAEGGFSHVYLVQL------VFPGKPPFEA------VLKRIFATDAMALRAVHEEV 82 Query: 373 RVSSLF-NHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF- 546 R L N + Q E +L G L D + +R + Sbjct: 83 RTMKLVSNQKRCVSYYGSEFFRTSKNQ----FEVLVLLEYCPCGGLID---FLNTRLQVR 135 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 S ++L+I + E + MH L PP H D+K NVL+ L DFGS+ Sbjct: 136 LSEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIENVLLAAPNSYK----LCDFGSACHP 191 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 ++ +EA +L+ + + +R PE+ + IDE++DIW+LG Y + Y + Sbjct: 192 IPGAKTAAEAKQLEYDIEKFTTWQYRCPEMINVHKGFGIDEKSDIWALGVLFYKLCYYTT 251 Query: 907 PFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 PFE+ AIMN +P PPY D L + ++ +LQ P RP+I Sbjct: 252 PFEH-------QGLAAIMNVSYAFPTF--PPYSDRLKRLISTLLQQYPWQRPNIYQTFCE 302 Query: 1087 VDKL 1098 + K+ Sbjct: 303 ICKM 306
>Q8IBS5:CDPK4_PLAF7 Calcium-dependent protein kinase 4 - Plasmodium falciparum (isolate| 3D7) Length = 528 Score = 82.8 bits (203), Expect = 3e-15 Identities = 72/250 (28%), Positives = 116/250 (46%) Frame = +1 Query: 163 DVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSR 342 +V NE+ ++ ++ +G+G F V L +RD+H H YA+K + S+ Sbjct: 63 NVVFNEQ-YKGIKILGKGSFGEVIL----------SRDKHTGH-----EYAIKVI---SK 103 Query: 343 EQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAA 522 + VK + SL LL +LDH I + ++ YL+ V+ G LFD Sbjct: 104 KH---VKRKTDKESLLREVELLKMLDHINIMKLYEFFEDNNYYYLVSDVYTGGELFDEII 160 Query: 523 VMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLM 702 SRK FY + D RI +QI G+ +MH + H D+KP N+L+ + + + ++ Sbjct: 161 ---SRKRFYEI-DAARIIKQILSGITYMHKNN--VVHRDLKPENILLETKNKEDMIIKII 214 Query: 703 DFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTL 882 DFG S + + + +A + AP++ H DE+ DIWS G L Sbjct: 215 DFGLSTHFEYSKKMKDKI----------GTAYYIAPDVL----HGTYDEKCDIWSCGVIL 260 Query: 883 YAIMYGVSPF 912 Y ++ G PF Sbjct: 261 YILLSGCPPF 270
>Q7RJG2:CDPK4_PLAYO Calcium-dependent protein kinase 4 - Plasmodium yoelii yoelii| Length = 528 Score = 81.3 bits (199), Expect = 9e-15 Identities = 72/250 (28%), Positives = 115/250 (46%) Frame = +1 Query: 163 DVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSR 342 +V NE+ ++ ++ +G+G F V L K D+H H YA+K + S+ Sbjct: 63 NVVFNEQ-YKGIKILGKGSFGEVILSK----------DKHTGH-----EYAIKVI---SK 103 Query: 343 EQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAA 522 + VK + SL LL +LDH I + ++ YL+ V+ G LFD Sbjct: 104 KH---VKRKTDKQSLLREVELLKMLDHINIMKLYEFFEDNNYYYLVSDVYSGGELFDEII 160 Query: 523 VMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLM 702 SRK FY V D RI +Q+ G+ +MH + H D+KP N+L+ + + + ++ Sbjct: 161 ---SRKRFYEV-DAARIIKQVLSGITYMHKNN--VVHRDLKPENILLETKNKEDMIIKII 214 Query: 703 DFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTL 882 DFG S + + + +A + AP++ H DE+ DIWS G L Sbjct: 215 DFGLSTHFEYSKKMKDKI----------GTAYYIAPDVL----HGTYDEKCDIWSCGVIL 260 Query: 883 YAIMYGVSPF 912 Y ++ G PF Sbjct: 261 YILLSGCPPF 270
>P62345:CDPK4_PLABA Calcium-dependent protein kinase 4 - Plasmodium berghei (strain| Anka) Length = 528 Score = 81.3 bits (199), Expect = 9e-15 Identities = 72/250 (28%), Positives = 115/250 (46%) Frame = +1 Query: 163 DVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSR 342 +V NE+ ++ ++ +G+G F V L K D+H H YA+K + S+ Sbjct: 63 NVVFNEQ-YKGIKILGKGSFGEVILSK----------DKHTGH-----EYAIKVI---SK 103 Query: 343 EQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAA 522 + VK + SL LL +LDH I + ++ YL+ V+ G LFD Sbjct: 104 KH---VKRKTDKQSLLREVELLKMLDHINIMKLYEFFEDNNYYYLVSDVYSGGELFDEII 160 Query: 523 VMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLM 702 SRK FY V D RI +Q+ G+ +MH + H D+KP N+L+ + + + ++ Sbjct: 161 ---SRKRFYEV-DAARIIKQVLSGITYMHKNN--VVHRDLKPENILLETKNKEDMIIKII 214 Query: 703 DFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTL 882 DFG S + + + +A + AP++ H DE+ DIWS G L Sbjct: 215 DFGLSTHFEYSKKMKDKI----------GTAYYIAPDVL----HGTYDEKCDIWSCGVIL 260 Query: 883 YAIMYGVSPF 912 Y ++ G PF Sbjct: 261 YILLSGCPPF 270
>P59895:NEK6_RAT Serine/threonine-protein kinase Nek6 - Rattus norvegicus (Rat)| Length = 313 Score = 79.3 bits (194), Expect = 3e-14 Identities = 78/298 (26%), Positives = 122/298 (40%), Gaps = 4/298 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKV----LIQSREQLD 354 F++ ++IG G F+ VY + DR T A+KKV ++ ++ + D Sbjct: 45 FQIEKKIGRGQFSEVY-------KATCLLDRK--------TVALKKVQIFEMMDAKARQD 89 Query: 355 LVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 VKE I + NHPN++ LD I +E ++ + G L + Sbjct: 90 CVKE-IGLLKQLNHPNIIKYLDSFIE---------DNELNIVLELADAGDLSQMIKYFKK 139 Query: 535 RKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGS 714 +K V + F Q+C ++HMHS H D+KP NV +T + L D G Sbjct: 140 QKRLIPERTVWKYFVQLCSAVEHMHSRR--VMHRDIKPANVFITA----TGIVKLGDLGL 193 Query: 715 SRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 R ++ + + + +P R E + ++DIWSLGC LY + Sbjct: 194 GRFFSSETTAAHSLV-----GTPYYMSPERIHE-------NGYNFKSDIWSLGCLLYEMA 241 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHI 1068 SPF G+ L Q +P LP Y + L + V+ + P P RP I Sbjct: 242 ALQSPF---YGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPNHRPDI 296
>Q9ES70:NEK6_MOUSE Serine/threonine-protein kinase Nek6 - Mus musculus (Mouse)| Length = 313 Score = 79.3 bits (194), Expect = 3e-14 Identities = 78/298 (26%), Positives = 122/298 (40%), Gaps = 4/298 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKV----LIQSREQLD 354 F++ ++IG G F+ VY + DR T A+KKV ++ ++ + D Sbjct: 45 FQIEKKIGRGQFSEVY-------KATCLLDRK--------TVALKKVQIFEMMDAKARQD 89 Query: 355 LVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 VKE I + NHPN++ LD I +E ++ + G L + Sbjct: 90 CVKE-IGLLKQLNHPNIIKYLDSFIE---------DNELNIVLELADAGDLSQMIKYFKK 139 Query: 535 RKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGS 714 +K V + F Q+C ++HMHS H D+KP NV +T + L D G Sbjct: 140 QKRLIPERTVWKYFVQLCSAVEHMHSRR--VMHRDIKPANVFITA----TGIVKLGDLGL 193 Query: 715 SRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 R ++ + + + +P R E + ++DIWSLGC LY + Sbjct: 194 GRFFSSETTAAHSLV-----GTPYYMSPERIHE-------NGYNFKSDIWSLGCLLYEMA 241 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHI 1068 SPF G+ L Q +P LP Y + L + V+ + P P RP I Sbjct: 242 ALQSPF---YGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDI 296
>Q9HC98:NEK6_HUMAN Serine/threonine-protein kinase Nek6 - Homo sapiens (Human)| Length = 313 Score = 79.0 bits (193), Expect = 4e-14 Identities = 78/298 (26%), Positives = 122/298 (40%), Gaps = 4/298 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKV----LIQSREQLD 354 F++ ++IG G F+ VY + DR T A+KKV ++ ++ + D Sbjct: 45 FQIEKKIGRGQFSEVY-------KATCLLDRK--------TVALKKVQIFEMMDAKARQD 89 Query: 355 LVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 VKE I + NHPN++ LD I +E ++ + G L + Sbjct: 90 CVKE-IGLLKQLNHPNIIKYLDSFIE---------DNELNIVLELADAGDLSQMIKYFKK 139 Query: 535 RKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGS 714 +K V + F Q+C ++HMHS H D+KP NV +T + L D G Sbjct: 140 QKRLIPERTVWKYFVQLCSAVEHMHS--RRVMHRDIKPANVFIT----ATGVVKLGDLGL 193 Query: 715 SRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 R ++ + + + +P R E + ++DIWSLGC LY + Sbjct: 194 GRFFSSETTAAHSLV-----GTPYYMSPERIHE-------NGYNFKSDIWSLGCLLYEMA 241 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHI 1068 SPF G+ L Q +P LP Y + L + V+ + P P RP I Sbjct: 242 ALQSPF---YGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDI 296
>Q6P3R8:NEK5_HUMAN Serine/threonine-protein kinase Nek5 - Homo sapiens (Human)| Length = 708 Score = 77.0 bits (188), Expect = 2e-13 Identities = 79/312 (25%), Positives = 127/312 (40%), Gaps = 3/312 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++ V++ IG+G F YL K S +K+ IQ +E K Sbjct: 3 KYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKE----------INFEKMPIQEKEAS---K 49 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 +E+ + HPN++ + + +++ G L + + R Sbjct: 50 KEVILLEKMKHPNIVAFFNSF---------QENGRLFIVMEYCDGGDLMKR--INRQRGV 98 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 +S +L F QI GLKH+H D H D+K N+ +++ +A L DFG +R Sbjct: 99 LFSEDQILGWFVQISLGLKHIH--DRKILHRDIKAQNIFLSKN---GMVAKLGDFGIARV 153 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFR-APELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 N + E A P+ +PE+ + + +TDIWSLGC LY + Sbjct: 154 LNNSM----------ELARTCIGTPYYLSPEICQ---NKPYNNKTDIWSLGCVLYELCTL 200 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PFE G +LQ ++ SP + LH ++ + Q P RP IN IL Sbjct: 201 KHPFE------GNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSIL 254 Query: 1081 LH--VDKLVEKY 1110 ++ L+ KY Sbjct: 255 KRPFLENLIPKY 266
>P51956:NEK3_HUMAN Serine/threonine-protein kinase Nek3 - Homo sapiens (Human)| Length = 506 Score = 75.9 bits (185), Expect = 4e-13 Identities = 85/314 (27%), Positives = 133/314 (42%), Gaps = 4/314 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKV-LIQSREQLDLVK 363 + VLR IGEG F LV+ H S + +AMK++ L +S + Sbjct: 4 YMVLRMIGEGSFGRALLVQ---------------HESSNQMFAMKEIRLPKSFSNTQNSR 48 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 +E + + HPN I+A K + H Y++ G L + Q + + Sbjct: 49 KEAVLLAKMKHPN--------IVAFKESFEAEGH-LYIVMEYCDGGDLMQK--IKQQKGK 97 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 + +L F Q+C G+ H+H H D+K N+ +T Q G+ L DFGS+R Sbjct: 98 LFPEDMILNWFTQMCLGVNHIHK--KRVLHRDIKSKNIFLT-QNGKVKLG---DFGSARL 151 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAP-ELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 N + +A + P+ P E+W+ + + ++DIWSLGC LY + Sbjct: 152 LSNPMA----------FACTYVGTPYYVPPEIWE---NLPYNNKSDIWSLGCILYELCTL 198 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PF+ S +L L + + LPS Y L V M + P+ RP +L Sbjct: 199 KHPFQ---ANSWKNLILKVCQGCIS--PLPS-HYSYELQFLVKQMFKRNPSHRPSATTLL 252 Query: 1081 LH--VDKLVEKYSP 1116 V +LV+K P Sbjct: 253 SRGIVARLVQKCLP 266
>P22517:KCC2_YEAST Calcium/calmodulin-dependent protein kinase II - Saccharomyces| cerevisiae (Baker's yeast) Length = 447 Score = 73.2 bits (178), Expect = 2e-12 Identities = 78/315 (24%), Positives = 136/315 (43%), Gaps = 5/315 (1%) Frame = +1 Query: 151 TGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVL 330 +G + ++N + R +G G F V ++ + D A +KK L Sbjct: 35 SGQPESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIK-----------ILLKKAL 83 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 + QL ++ EE+ + +HPN++ D + + Y++ + G LF Sbjct: 84 QGNNVQLQMLYEELSILQKLSHPNIVSFKDWF---------ESKDKFYIVTQLATGGELF 134 Query: 511 DNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 D + SR +F V D + I QI +++MHS + H D+KP NVL + +PL Sbjct: 135 DR---ILSRGKFTEV-DAVEIIVQILGAVEYMHSKN--VVHRDLKPENVLYVDKSENSPL 188 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSL 870 + DFG ++ Q++ + + S + APE+ H + DIWS+ Sbjct: 189 V-IADFGIAK----QLKGEEDLIYKAAG-----SLGYVAPEVLTQDGHG---KPCDIWSI 235 Query: 871 GCTLYAIMYGVSPFEYALGES-GGSLQLAIMNAQLKWPQLPSPPYPDAL----HKFVTWM 1035 G Y ++ G SPF + ES G ++ + ++P PY D + +F+ Sbjct: 236 GVITYTLLCGYSPF---IAESVEGFMEECTAS---RYPVTFHMPYWDNISIDVKRFILKA 289 Query: 1036 LQPQPAMRPHINDIL 1080 L+ PA RP ++L Sbjct: 290 LRLNPADRPTATELL 304
>Q8R9T6:PKN1_THETN Probable serine/threonine-protein kinase Sps1 - Thermoanaerobacter| tengcongensis Length = 625 Score = 72.8 bits (177), Expect = 3e-12 Identities = 75/293 (25%), Positives = 121/293 (41%), Gaps = 1/293 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R+ +L +IGEGG A VY K H + A + D + K K Sbjct: 9 RYEILEKIGEGGMAKVYKAKCHLLNRIVAIKILRPEFAADENFVKK------------FK 56 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E + ++ +HPN++ + D +GD Y + ++ G +++ Sbjct: 57 RESQAAASLSHPNIVGIYD------VGQEGD----IYYIVMEYVKGRTLKE--LIRENGG 104 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 V + I Q+C L H H H D+KP N+LVT + + + DFG +R Sbjct: 105 PLEVKRAVEIASQVCRALDHAHK--NKIIHRDIKPQNILVTDED----VVKVTDFGIARA 158 Query: 724 ARNQ-IRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 A I + + +A + +PE + +DERTDI+SLG L+ ++ G Sbjct: 159 ANGATITYTGDVIG---------TAYYFSPEQ---AKGSIVDERTDIYSLGIVLFEMLTG 206 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 PFE G+S S+ L + + P + P+ L K V Q P +R Sbjct: 207 KVPFE---GDSPISVALKHIQEDILPPSRLNEKVPEELDKIVLKATQKDPNLR 256
>Q5RDG7:MYLK3_PONPY Putative myosin light chain kinase 3 - Pongo pygmaeus (Orangutan)| Length = 819 Score = 72.8 bits (177), Expect = 3e-12 Identities = 70/258 (27%), Positives = 114/258 (44%) Frame = +1 Query: 313 AMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVH 492 A K + ++S + + VK EI + + +H NL+ L D A +S H L+ Sbjct: 542 AAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYD----AFES-----KHSCTLVMEYV 592 Query: 493 LDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQ 672 G LFD + K + LDV+ +QICEG+ ++H H D+KP N+L Q Sbjct: 593 DGGELFDR---ITDEKYHLTELDVVLFTRQICEGVHYLHQ--HYILHLDLKPENILCVNQ 647 Query: 673 KGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDER 852 G ++DFG +R + + E L++ E F APE+ ++ + Sbjct: 648 TGHQ--IKIIDFGLARRYKPR-----EKLKVNFGTPE-----FLAPEV---VNYEFVSFP 692 Query: 853 TDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTW 1032 TD+WS+G Y ++ G+SPF LGE+ I+N + + FV+ Sbjct: 693 TDMWSVGVITYMLLSGLSPF---LGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSR 749 Query: 1033 MLQPQPAMRPHINDILLH 1086 +L + + R L H Sbjct: 750 LLVKEESCRMSATQCLKH 767
>Q32MK0:MYLK3_HUMAN Putative myosin light chain kinase 3 - Homo sapiens (Human)| Length = 819 Score = 72.8 bits (177), Expect = 3e-12 Identities = 70/258 (27%), Positives = 114/258 (44%) Frame = +1 Query: 313 AMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVH 492 A K + ++S + + VK EI + + +H NL+ L D A +S H L+ Sbjct: 542 AAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYD----AFES-----KHSCTLVMEYV 592 Query: 493 LDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQ 672 G LFD + K + LDV+ +QICEG+ ++H H D+KP N+L Q Sbjct: 593 DGGELFDR---ITDEKYHLTELDVVLFTRQICEGVHYLHQ--HYILHLDLKPENILCVNQ 647 Query: 673 KGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDER 852 G ++DFG +R + + E L++ E F APE+ ++ + Sbjct: 648 TGHQ--IKIIDFGLARRYKPR-----EKLKVNFGTPE-----FLAPEV---VNYEFVSFP 692 Query: 853 TDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTW 1032 TD+WS+G Y ++ G+SPF LGE+ I+N + + FV+ Sbjct: 693 TDMWSVGVITYMLLSGLSPF---LGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSR 749 Query: 1033 MLQPQPAMRPHINDILLH 1086 +L + + R L H Sbjct: 750 LLVKEKSCRMSATQCLKH 767
>Q8VCR8:MYLK2_MOUSE Myosin light chain kinase 2, skeletal/cardiac muscle - Mus musculus| (Mouse) Length = 613 Score = 72.4 bits (176), Expect = 4e-12 Identities = 71/267 (26%), Positives = 118/267 (44%), Gaps = 2/267 (0%) Frame = +1 Query: 313 AMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVH 492 A K + Q+ + ++V EI V + NH NL+ L +A I + SHE L Sbjct: 329 AAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQL--YAAI-------ETSHEIILFMEYI 379 Query: 493 LDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQ 672 G LF+ + +D + +QIC+G+ MH + H D+KP N+L Sbjct: 380 EGGELFERIV---DEDYHLTEVDTMVFVRQICDGILFMHKMR--VLHLDLKPENILCVNT 434 Query: 673 KGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDER 852 G L ++DFG +R + +E L++ E F +PE+ ++ I ++ Sbjct: 435 TGH--LVKIIDFGLARRY-----NPNEKLKVNFGTPE-----FLSPEV---VNYDQISDK 479 Query: 853 TDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTW 1032 TD+WSLG Y ++ G+SPF LG+ +++A + + D FV+ Sbjct: 480 TDMWSLGVITYMLLSGLSPF---LGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSN 536 Query: 1033 MLQPQPAMRPHINDILLH--VDKLVEK 1107 +L + R L H ++ L EK Sbjct: 537 LLTKDQSARMSAEQCLAHPWLNNLAEK 563
>P18652:KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha - Gallus gallus (Chicken)| Length = 752 Score = 72.0 bits (175), Expect = 5e-12 Identities = 75/305 (24%), Positives = 124/305 (40%) Frame = +1 Query: 220 FAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHP 399 F+ Y+VKE + + H + + YA+K + R+ + ++ +R HP Sbjct: 431 FSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQ---HP 487 Query: 400 NLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQ 579 N II +K D + YL+ + G L D R++F+S + + Sbjct: 488 N--------IITLKDVYDDGKY-VYLVTELMRGGELLDKIL----RQKFFSEREASSVLH 534 Query: 580 QICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEAL 759 IC+ ++++HS H D+KP N+L + G + DFG ++ Q+R+ + L Sbjct: 535 TICKTVEYLHSQG--VVHRDLKPSNILYVDESGNPESIRICDFGFAK----QLRAENGLL 588 Query: 760 RLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGG 939 + A F APE+ + DE DIWSLG LY ++ G +PF ++ Sbjct: 589 MTPCYTAN-----FVAPEVLKRQGY---DEGCDIWSLGVLLYTMLAGCTPFANGPSDTPE 640 Query: 940 SLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP* 1119 + I + D V+ ML P R +L H + P Sbjct: 641 EILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQ 700 Query: 1120 SQLAY 1134 SQL Y Sbjct: 701 SQLNY 705 Score = 58.9 bits (141), Expect = 5e-08 Identities = 72/273 (26%), Positives = 121/273 (44%), Gaps = 3/273 (1%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 +F +L+ +G+G F V+LV++ +H+ YAMK + + + D V+ Sbjct: 79 QFELLKVLGQGSFGKVFLVRKITPPDS-------NHL-----YAMKVLKKATLKVRDRVR 126 Query: 364 EEIRVSSL--FNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 +I L NHP ++ L H T+G + YL+ G LF S+ Sbjct: 127 TKIERDILADVNHPFVVKL--HYAF---QTEG----KLYLILDFLRGGDLFTRL----SK 173 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + ++ DV ++ GL H+HSL Y D+KP N+L+ ++G L DFG S Sbjct: 174 EVMFTEEDVKFYLAELALGLDHLHSLGIIY--RDLKPENILLD-EEGHIKLT---DFGLS 227 Query: 718 RPARNQIRSRSEALRLQEWAAEHC-SAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 + EA+ ++ A C + + APE+ + H+ D WS G ++ ++ Sbjct: 228 K----------EAIDHEKKAYSFCGTVEYMAPEVVNRQGHS---HSADWWSYGVLMFEML 274 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPS 993 G PF+ G+ I+ A+L PQ S Sbjct: 275 TGSLPFQ---GKDRKETMTLILKAKLGMPQFLS 304
>Q9UEE5:ST17A_HUMAN Serine/threonine-protein kinase 17A - Homo sapiens (Human)| Length = 414 Score = 71.2 bits (173), Expect = 9e-12 Identities = 62/209 (29%), Positives = 95/209 (45%), Gaps = 2/209 (0%) Frame = +1 Query: 466 EAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVK 645 E L+ G +FD R+E + DV R+ +QI EG+ +H+ D H D+K Sbjct: 133 EMILVLEYAAGGEIFDQCVA--DREEAFKEKDVQRLMRQILEGVHFLHTRD--VVHLDLK 188 Query: 646 PGNVLVTRQKGQAPLATL--MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELW 819 P N+L+T ++PL + +DFG SR +N SE LR E+ APE+ Sbjct: 189 PQNILLT---SESPLGDIKIVDFGLSRILKN-----SEELREIMGTPEYV-----APEIL 235 Query: 820 DCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPP 999 S+ I TD+WS+G Y ++ G+SPF LG L I L + + Sbjct: 236 ---SYDPISMATDMWSIGVLTYVMLTGISPF---LGNDKQETFLNISQMNLSYSEEEFDV 289 Query: 1000 YPDALHKFVTWMLQPQPAMRPHINDILLH 1086 ++ F+ +L +P R + L H Sbjct: 290 LSESAVDFIRTLLVKKPEDRATAEECLKH 318
>Q9R0A5:NEK3_MOUSE Serine/threonine-protein kinase Nek3 - Mus musculus (Mouse)| Length = 511 Score = 71.2 bits (173), Expect = 9e-12 Identities = 81/302 (26%), Positives = 125/302 (41%), Gaps = 4/302 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 + VLR IG+G F LV + S + T+AMK++ + + KE Sbjct: 4 YTVLRVIGQGSFGRALLVLQE---------------SSNQTFAMKEIRLLKSDTQTSRKE 48 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHL--DGTLFDNAAVMQSRK 540 + ++ + HPN I+A K + + E YL + G L + Q + Sbjct: 49 AVLLAKM-KHPN--------IVAFKES---FEAEGYLYIVMEYCDGGDLMQR--IKQQKG 94 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 + +L F QIC G+ H+H H D+K NV +T G+ L DFGS+R Sbjct: 95 NLFPEDTILNWFIQICLGVNHIHKRR--VLHRDIKSKNVFLTHN-GKVKLG---DFGSAR 148 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAPFRAP-ELWDCPSHADIDERTDIWSLGCTLYAIMY 897 + + +A + P+ P E+W+ + + ++DIWSLGC LY + Sbjct: 149 LLSSPMA----------FACTYVGTPYYVPPEIWE---NLPYNNKSDIWSLGCILYELCA 195 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPP-YPDALHKFVTWMLQPQPAMRPHIND 1074 PF+ S +L L I P P P Y L V ML+ P+ RP Sbjct: 196 LKHPFQ---ANSWKNLILKICQG----PIHPLPALYSCKLQGLVKQMLKRNPSHRPSATT 248 Query: 1075 IL 1080 +L Sbjct: 249 LL 250
>P20689:MYLK2_RAT Myosin light chain kinase 2, skeletal/cardiac muscle - Rattus| norvegicus (Rat) Length = 610 Score = 71.2 bits (173), Expect = 9e-12 Identities = 71/269 (26%), Positives = 120/269 (44%), Gaps = 4/269 (1%) Frame = +1 Query: 313 AMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVH 492 A K + Q+ + ++V EI V + NH NL+ L A+++ SHE L Sbjct: 326 AAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYS----AIET-----SHEIILFMEYI 376 Query: 493 LDGTLFDNAAVMQSRKEFYSV--LDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVT 666 G LF+ E Y + +D + +QIC+G+ MH + H D+KP N+L Sbjct: 377 EGGELFERIV-----DEDYQLTEVDTMVFVRQICDGILFMHKMR--VLHLDLKPENILCV 429 Query: 667 RQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADID 846 G L ++DFG +R + +E L++ E F +PE+ ++ I Sbjct: 430 NTTGH--LVKIIDFGLARRY-----NPNEKLKVNFGTPE-----FLSPEV---VNYDQIS 474 Query: 847 ERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFV 1026 ++TD+WSLG Y ++ G+SPF LG+ +++A + + D FV Sbjct: 475 DKTDMWSLGVITYMLLSGLSPF---LGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFV 531 Query: 1027 TWMLQPQPAMRPHINDILLH--VDKLVEK 1107 + ++ + R L H ++ L EK Sbjct: 532 SNLITKDQSARMSAEQCLAHPWLNNLAEK 560
>Q9C098:DCLK3_HUMAN Serine/threonine-protein kinase DCLK3 - Homo sapiens (Human)| Length = 648 Score = 70.5 bits (171), Expect = 2e-11 Identities = 82/314 (26%), Positives = 124/314 (39%), Gaps = 11/314 (3%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMK---KVLIQSREQ 348 E+ + R IG+G FA V + + YAMK K ++ +E Sbjct: 353 EKHYETGRVIGDGNFAVVKECRHRETRQ---------------AYAMKIIDKSRLKGKE- 396 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 D+V EI + +HPN++ L H + + E YL+ G LFD A++ Sbjct: 397 -DMVDSEILIIQSLSHPNIVKL--HEVY-------ETDMEIYLILEYVQGGDLFD--AII 444 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 +S K + D + +C+ L HMH D H D+KP N+LV R + ++ L DF Sbjct: 445 ESVK--FPEPDAALMIMDLCKALVHMH--DKSIVHRDLKPENLLVQRNEDKSTTLKLADF 500 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLY 885 G ++ I + C P + APE+ S D+W+ G LY Sbjct: 501 GLAKHVVRPIFT-------------VCGTPTYVAPEIL---SEKGYGLEVDMWAAGVILY 544 Query: 886 AIMYGVSPF---EYALGESGGSLQLAIMNAQLKWPQLPSPPY----PDALHKFVTWMLQP 1044 ++ G PF E E +QL PPY DA V+ +L Sbjct: 545 ILLCGFPPFRSPERDQDELFNIIQLGHFEF--------LPPYWDNISDAAKDLVSRLLVV 596 Query: 1045 QPAMRPHINDILLH 1086 P R + +L H Sbjct: 597 DPKKRYTAHQVLQH 610
>Q9GM70:ST17A_RABIT Serine/threonine-protein kinase 17A - Oryctolagus cuniculus (Rabbit)| Length = 397 Score = 70.1 bits (170), Expect = 2e-11 Identities = 62/211 (29%), Positives = 97/211 (45%), Gaps = 2/211 (0%) Frame = +1 Query: 460 SHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHND 639 S E L+ G + D R E ++ DV R+ +QI EG+ +H+ D H D Sbjct: 114 SSEMILVLEYAAGGEISDQCVA--DRDEAFNEKDVQRLMRQILEGVHFLHTHD--VVHLD 169 Query: 640 VKPGNVLVTRQKGQAPLATL--MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPE 813 +KP N+L+T ++PL + +DFG SR +N SE LR E+ APE Sbjct: 170 LKPQNILLT---SESPLGDIKIVDFGLSRIVKN-----SEELREIMGTPEYV-----APE 216 Query: 814 LWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPS 993 + S+ I TD+WS+G Y ++ G+SPF LG++ L I L + + Sbjct: 217 IL---SYDPISMATDMWSIGVLTYVMLTGISPF---LGDNKQETFLNISQMNLSYSEEEF 270 Query: 994 PPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 ++ F+ +L +P R + L H Sbjct: 271 DTVSESAVDFIKKLLVKKPEDRATAEECLKH 301
>P27466:KCC1_YEAST Calcium/calmodulin-dependent protein kinase I - Saccharomyces| cerevisiae (Baker's yeast) Length = 446 Score = 70.1 bits (170), Expect = 2e-11 Identities = 65/251 (25%), Positives = 113/251 (45%), Gaps = 3/251 (1%) Frame = +1 Query: 169 WINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQ 348 ++N++++ + +G G F V K + D A +KK L ++ Q Sbjct: 31 YVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVK-----------ILIKKALKGNKVQ 79 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDW---SHEAYLLFPVHLDGTLFDNA 519 L+ + +E+ + +HPN I+A K DW + Y++ + G LFD Sbjct: 80 LEALYDELDILQRLHHPN--------IVAFK----DWFESKDKFYIITQLAKGGELFDRI 127 Query: 520 AVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATL 699 +K ++ D +RI +I +K+MHS + H D+KP N+L + ++PL + Sbjct: 128 L----KKGKFTEEDAVRILVEILSAVKYMHSQN--IVHRDLKPENLLYIDKSDESPLV-V 180 Query: 700 MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCT 879 DFG ++ R +S+ L + A S + APE+ H + DIWS+G Sbjct: 181 ADFGIAK------RLKSDEELLYKPAG---SLGYVAPEVLTQDGHG---KPCDIWSIGVI 228 Query: 880 LYAIMYGVSPF 912 Y ++ G S F Sbjct: 229 TYTLLCGYSAF 239
>P10666:KS6AB_XENLA Ribosomal protein S6 kinase 2 beta - Xenopus laevis (African clawed| frog) Length = 629 Score = 69.7 bits (169), Expect = 3e-11 Identities = 62/239 (25%), Positives = 104/239 (43%), Gaps = 1/239 (0%) Frame = +1 Query: 220 FAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFN-H 396 F VY V+E + + H + YA+K + R+ EEI + + H Sbjct: 412 FTDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKSKRDP----SEEIEILRRYGQH 467 Query: 397 PNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIF 576 PN++ L D + + YL+ + G L D R++F+S + + Sbjct: 468 PNIITLKDVY---------EECNSIYLVTELMRGGELLDRIL----RQKFFSEREACSVL 514 Query: 577 QQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEA 756 +C+ ++++HS H D+KP N+L + G + DFG S+ Q+R+ + Sbjct: 515 FTVCKTVEYLHSQG--VVHRDLKPSNILYVDESGDPESIRICDFGFSK----QLRAENGL 568 Query: 757 LRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGES 933 L + A F APE+ + DE DIWSLG LY ++ G +PF G++ Sbjct: 569 LMTPCYTAN-----FVAPEVLKRQGY---DEGCDIWSLGILLYTMLAGYTPFANGPGDT 619 Score = 54.7 bits (130), Expect = 9e-07 Identities = 69/274 (25%), Positives = 123/274 (44%), Gaps = 1/274 (0%) Frame = +1 Query: 175 NERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLD 354 ++ F +L+ +G+G F V+LV++ + A + V +KK ++ R+++ Sbjct: 58 DQSHFVLLKVLGQGSFGKVFLVRK--ITPPDANQLYAMKV-------LKKATLKVRDRVR 108 Query: 355 LVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 K E + + +HP ++ L H T+G + YL+ G LF S Sbjct: 109 -TKMERDILADVHHPFVVRL--HYAF---QTEG----KLYLILDFLRGGDLFTRL----S 154 Query: 535 RKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGS 714 ++ ++ DV ++ GL H+HSL Y D+KP N+L+ ++G L DFG Sbjct: 155 KEVMFTEEDVKFYLAELALGLDHLHSLGIIY--RDLKPENILLD-EEGHIKLT---DFGL 208 Query: 715 SRPARNQIRSRSEALRLQEWAAEHC-SAPFRAPELWDCPSHADIDERTDIWSLGCTLYAI 891 S+ EA+ ++ A C + + APE+ + H+ D WS G ++ + Sbjct: 209 SK----------EAIDHEKKAYSFCGTVEYMAPEVVNRQGHS---HGADWWSYGVLMFEM 255 Query: 892 MYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPS 993 + G PF+ G+ I+ A+L PQ S Sbjct: 256 LTGSLPFQ---GKDRKETMTLILKAKLGMPQFLS 286
>Q10452:GSK3_SCHPO Protein kinase gsk3 - Schizosaccharomyces pombe (Fission yeast)| Length = 387 Score = 69.7 bits (169), Expect = 3e-11 Identities = 79/297 (26%), Positives = 126/297 (42%), Gaps = 8/297 (2%) Frame = +1 Query: 292 VSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEA 471 + D A+K+VL R + E+++ + HPN++ L IA T GD S E Sbjct: 52 IESDSKAAIKRVLQDKRFK----NRELQIMRIMKHPNIVDL-----IAYYYTTGDNSDEV 102 Query: 472 YL-LFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKP 648 YL L + T++ + + +K +L+V Q+ L ++H+ H D+KP Sbjct: 103 YLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHASG--ICHRDIKP 160 Query: 649 GNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCP 828 N+L+ + G + L DFGS A+ + + CS +RAPEL Sbjct: 161 QNLLLDPENG---ILKLCDFGS---AKILVAGEPNVSYI-------CSRYYRAPEL--IF 205 Query: 829 SHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIM----NAQLKWPQLPSP 996 D DIWS GC + +M G F GESG + I+ + + +P Sbjct: 206 GATDYTHAIDIWSTGCVMAELMLGHPLFP---GESGIDQLVEIIKILGTPSREQIKTMNP 262 Query: 997 PYPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEK---YSP*SQLAYSVLTCFFF 1158 Y + H+F ++PQP R + L L+ K Y+P +L + C F Sbjct: 263 NYME--HRFP--QIRPQPLSRVFSRSVPLDALDLLSKMLQYTPTDRLTAAEAMCHPF 315
>Q3UIZ8:MYLK3_MOUSE Putative myosin light chain kinase 3 - Mus musculus (Mouse)| Length = 795 Score = 69.3 bits (168), Expect = 3e-11 Identities = 67/259 (25%), Positives = 115/259 (44%), Gaps = 1/259 (0%) Frame = +1 Query: 313 AMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVH 492 A K + +++ + + VK E+ + + +H NL+ L D S ++ L + Sbjct: 518 AAKIIKVKNVKDREDVKNEVNIMNQLSHVNLIQLYD----------AFESKSSFTLIMEY 567 Query: 493 LDG-TLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTR 669 +DG LFD + K + LDV+ +QICEG+ ++H H D+KP N+L Sbjct: 568 VDGGELFDR---ITDEKYHLTELDVVLFTRQICEGVHYLHQ--HYILHLDLKPENILCVS 622 Query: 670 QKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDE 849 Q G ++DFG +R + + E L++ E F APE+ ++ + Sbjct: 623 QTGHQ--IKIIDFGLARRYKPR-----EKLKVNFGTPE-----FLAPEV---VNYEFVSF 667 Query: 850 RTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVT 1029 TD+WS+G Y ++ G+SPF LGE+ I+N + + FV+ Sbjct: 668 PTDMWSVGVITYMLLSGLSPF---LGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVS 724 Query: 1030 WMLQPQPAMRPHINDILLH 1086 +L + + R L H Sbjct: 725 RLLVKEKSCRMSATQCLKH 743
>Q15418:KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 - Homo sapiens (Human)| Length = 735 Score = 69.3 bits (168), Expect = 3e-11 Identities = 74/308 (24%), Positives = 126/308 (40%) Frame = +1 Query: 220 FAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHP 399 F+ Y+VKE + + H + + YA+K + R+ + ++ +R HP Sbjct: 414 FSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQ---HP 470 Query: 400 NLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQ 579 N II +K D H YL+ + G L D R++F+S + + Sbjct: 471 N--------IITLKDVYDDGKH-VYLVTELMRGGELLDKIL----RQKFFSEREASFVLH 517 Query: 580 QICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEAL 759 I + ++++HS H D+KP N+L + G + DFG ++ Q+R+ + L Sbjct: 518 TIGKTVEYLHSQG--VVHRDLKPSNILYVDESGNPECLRICDFGFAK----QLRAENGLL 571 Query: 760 RLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGG 939 + A F APE+ + DE DIWSLG LY ++ G +PF ++ Sbjct: 572 MTPCYTAN-----FVAPEVLKRQGY---DEGCDIWSLGILLYTMLAGYTPFANGPSDTPE 623 Query: 940 SLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP* 1119 + I + + + V+ ML P R +L H + P Sbjct: 624 EILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQ 683 Query: 1120 SQLAYSVL 1143 SQL++ L Sbjct: 684 SQLSHQDL 691 Score = 58.2 bits (139), Expect = 8e-08 Identities = 72/273 (26%), Positives = 119/273 (43%), Gaps = 4/273 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMK---KVLIQSREQLDL 357 F +L+ +G+G F V+LV R + YAMK K ++ R+++ Sbjct: 62 FELLKVLGQGSFGKVFLV------------RKVTRPDSGHLYAMKVLKKATLKVRDRVR- 108 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 K E + + NHP ++ L H T+G + YL+ G LF S+ Sbjct: 109 TKMERDILADVNHPFVVKL--HYAF---QTEG----KLYLILDFLRGGDLFTRL----SK 155 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + ++ DV ++ GL H+HSL Y D+KP N+L+ ++G L DFG S Sbjct: 156 EVMFTEEDVKFYLAELALGLDHLHSLGIIY--RDLKPENILLD-EEGHIKLT---DFGLS 209 Query: 718 RPARNQIRSRSEALRLQEWAAEHC-SAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 + EA+ ++ A C + + APE+ + H+ D WS G ++ ++ Sbjct: 210 K----------EAIDHEKKAYSFCGTVEYMAPEVVNRQGHS---HSADWWSYGVLMFEML 256 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPS 993 G PF+ G+ I+ A+L PQ S Sbjct: 257 TGSLPFQ---GKDRKETMTLILKAKLGMPQFLS 286
>Q63531:KS6A1_RAT Ribosomal protein S6 kinase alpha-1 - Rattus norvegicus (Rat)| Length = 735 Score = 68.9 bits (167), Expect = 5e-11 Identities = 74/308 (24%), Positives = 126/308 (40%) Frame = +1 Query: 220 FAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHP 399 F+ Y+VKE + + H + + YA+K + R+ + ++ +R HP Sbjct: 414 FSDGYIVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQ---HP 470 Query: 400 NLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQ 579 N II +K D H YL+ + G L D R++F+S + + Sbjct: 471 N--------IITLKDVYDDSKH-VYLVTELMRGGELLDKIL----RQKFFSEREASFVLY 517 Query: 580 QICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEAL 759 I + ++++HS H D+KP N+L + G + DFG ++ Q+R+ + L Sbjct: 518 TISKTVEYLHSQG--VVHRDLKPSNILYVDESGNPECLRICDFGFAK----QLRAENGLL 571 Query: 760 RLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGG 939 + A F APE+ + DE DIWSLG LY ++ G +PF ++ Sbjct: 572 MTPCYTAN-----FVAPEVLKRQGY---DEGCDIWSLGVLLYTMLAGYTPFANGPSDTPE 623 Query: 940 SLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP* 1119 + I + + + V+ ML P R +L H + P Sbjct: 624 EILTRISSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQ 683 Query: 1120 SQLAYSVL 1143 SQL++ L Sbjct: 684 SQLSHQDL 691 Score = 57.8 bits (138), Expect = 1e-07 Identities = 69/270 (25%), Positives = 118/270 (43%), Gaps = 1/270 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F +L+ +G+G F V+LV+ + P + +KK ++ R+++ K Sbjct: 62 FELLKVLGQGSFGKVFLVR---------KVTRPDNGHLYAMKVLKKATLKVRDRVR-TKM 111 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 E + + NHP ++ L H T+G + YL+ G LF S++ Sbjct: 112 ERDILADVNHPFVVKL--HYAF---QTEG----KLYLILDFLRGGDLFTRL----SKEVM 158 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 ++ DV ++ GL H+HSL Y D+KP N+L+ ++G L DFG S+ Sbjct: 159 FTEEDVKFYLAELALGLDHLHSLGIIY--RDLKPENILLD-EEGHIKLT---DFGLSK-- 210 Query: 727 RNQIRSRSEALRLQEWAAEHC-SAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 EA+ ++ A C + + APE+ + H D WS G ++ ++ G Sbjct: 211 --------EAIDHEKKAYSFCGTVEYMAPEVVNRQGHT---HSADWWSYGVLMFEMLTGS 259 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPS 993 PF+ G+ I+ A+L PQ S Sbjct: 260 LPFQ---GKDRKETMTLILKAKLGMPQFLS 286
>P54665:CC2H2_TRYBB Cell division control protein 2 homolog 2 - Trypanosoma brucei brucei| Length = 345 Score = 68.9 bits (167), Expect = 5e-11 Identities = 80/334 (23%), Positives = 138/334 (41%), Gaps = 3/334 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R+ + ++GEG + VY ++ A R P V+ G V + ++ L++ Sbjct: 45 RYSRIEKVGEGSYGIVYKCHDNFTGRTVAMKRIPLIVNDGG------VPSTAVREVSLLR 98 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E NHP ++ LLD + HEA LL + + D +++ R Sbjct: 99 E-------LNHPYVVRLLDVVL-----------HEAKLL--LIFEYMEQDLQGMLKQRNT 138 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 + + RI Q+ GL HS + H D+KP N+L+ R++ LA DFG R Sbjct: 139 AFVGGKLRRIMFQLLLGLHECHSRR--FVHRDIKPSNILIDRKESVVKLA---DFGLGRA 193 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 R + LQ + E + +RAPE+ D+WS+GC + Sbjct: 194 FR---------VPLQTYTTEVMTLWYRAPEV--LLGDKQYLPAVDVWSMGCVFAELARRR 242 Query: 904 SPF--EYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDI 1077 S F + A+ + QL + W + S P+ + F W +P P ++D Sbjct: 243 SLFAGDTAINQLFSIFQLLGTPTEATWRGVTSLPHHNV--NFPRWTAKPLRTAVPALDDD 300 Query: 1078 LLHVDKLVEKYSP*SQL-AYSVLTCFFFIRLQRE 1176 + + + + Y+P ++ AY L +F ++ E Sbjct: 301 GVDLLRRMLCYNPRERITAYEALQHSYFDEVREE 334
>P52304:POLO_DROME Serine/threonine-protein kinase polo - Drosophila melanogaster (Fruit| fly) Length = 576 Score = 68.6 bits (166), Expect = 6e-11 Identities = 74/309 (23%), Positives = 127/309 (41%), Gaps = 6/309 (1%) Frame = +1 Query: 172 INERR-FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQ 348 IN+R+ ++ +R G+GGFA Y + + + A G KK++I+ Q Sbjct: 19 INQRKTYKRMRFFGKGGFAKCYEIIDVETDDVFA-----------GKIVSKKLMIK-HNQ 66 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +EI + NHPN++ ++ + S Y++ + ++ + + Sbjct: 67 KEKTAQEITIHRSLNHPNIVKFHNYF---------EDSQNIYIVLELCKKRSMME----L 113 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNV----LVTRQKGQAPLAT 696 R++ + + QI +G+K++H D H D+K GN+ L+ + G LAT Sbjct: 114 HKRRKSITEFECRYYIYQIIQGVKYLH--DNRIIHRDLKLGNLFLNDLLHVKIGDFGLAT 171 Query: 697 LMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLG 873 +++ R C P + APE+ H+ DIWS+G Sbjct: 172 RIEYEGERKKTL------------------CGTPNYIAPEILTKKGHSF---EVDIWSIG 210 Query: 874 CTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPA 1053 C +Y ++ G PFE + S I + + P P D V MLQP P Sbjct: 211 CVMYTLLVGQPPFETKTLKDTYS---KIKKCEYRVPSYLRKPAAD----MVIAMLQPNPE 263 Query: 1054 MRPHINDIL 1080 RP I +L Sbjct: 264 SRPAIGQLL 272
>P10665:KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha - Xenopus laevis (African clawed| frog) Length = 733 Score = 68.6 bits (166), Expect = 6e-11 Identities = 63/239 (26%), Positives = 106/239 (44%), Gaps = 1/239 (0%) Frame = +1 Query: 220 FAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFN-H 396 F VY V+E + + H + YA+K + R+ EEI + + H Sbjct: 412 FMDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKTKRDP----SEEIEILRRYGQH 467 Query: 397 PNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIF 576 PN IIA+K + + Y++ + G L D R++F+S + + Sbjct: 468 PN--------IIALKDVYKE-GNSIYVVTELMRGGELLDRIL----RQKFFSEREASSVL 514 Query: 577 QQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEA 756 +C+ ++++HS H D+KP N+L + G + DFG ++ Q+R+ + Sbjct: 515 FTVCKTVENLHSQG--VVHRDLKPSNILYVDESGDPESIRICDFGFAK----QLRADNGL 568 Query: 757 LRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGES 933 L + A F APE+ + DE DIWSLG LY ++ G +PF LG++ Sbjct: 569 LMTPCYTAN-----FVAPEVLKRQGY---DEGCDIWSLGILLYTMLAGYTPFANGLGDT 619 Score = 54.3 bits (129), Expect = 1e-06 Identities = 69/270 (25%), Positives = 121/270 (44%), Gaps = 1/270 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F +L+ +G+G F V+LV++ + A + V +KK ++ R+++ K Sbjct: 62 FVLLKVLGQGSFGKVFLVRK--ITPPDANQLYAMKV-------LKKATLKVRDRVR-TKM 111 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 E + + +HP ++ L H T+G + YL+ G LF S++ Sbjct: 112 ERDILADVHHPFVVRL--HYAF---QTEG----KLYLILDFLRGGDLFTRL----SKEVM 158 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 ++ DV ++ GL H+HSL Y D+KP N+L+ ++G L DFG S+ Sbjct: 159 FTEEDVKFYLAELALGLDHLHSLGIIY--RDLKPENILLD-EEGHIKLT---DFGLSK-- 210 Query: 727 RNQIRSRSEALRLQEWAAEHC-SAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 EA+ ++ A C + + APE+ + H+ D WS G ++ ++ G Sbjct: 211 --------EAIDHEKKAYSFCGTVEYMAPEVVNRQGHS---HSADWWSYGVLMFEMLTGS 259 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPS 993 PF+ G+ I+ A+L PQ S Sbjct: 260 LPFQ---GKDRKETMTLILKAKLGMPQFLS 286
>P18653:KS6A1_MOUSE Ribosomal protein S6 kinase alpha-1 - Mus musculus (Mouse)| Length = 724 Score = 68.6 bits (166), Expect = 6e-11 Identities = 74/308 (24%), Positives = 126/308 (40%) Frame = +1 Query: 220 FAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHP 399 F+ Y+VKE + + H + + YA+K + R+ + ++ +R HP Sbjct: 403 FSDGYVVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQ---HP 459 Query: 400 NLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQ 579 N II +K D H YL+ + G L D R++F+S + + Sbjct: 460 N--------IITLKDVYDDGKH-VYLVTELMRGGELLDKIL----RQKFFSEREASFVLH 506 Query: 580 QICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEAL 759 I + ++++HS H D+KP N+L + G + DFG ++ Q+R+ + L Sbjct: 507 TISKTVEYLHSQG--VVHRDLKPSNILYVDESGNPECLRICDFGFAK----QLRAENGLL 560 Query: 760 RLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGG 939 + A F APE+ + DE DIWSLG LY ++ G +PF ++ Sbjct: 561 MTPCYTAN-----FVAPEVLKRQGY---DEGCDIWSLGILLYTMLAGYTPFANGPSDTPE 612 Query: 940 SLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP* 1119 + I + + + V+ ML P R +L H + P Sbjct: 613 EILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQ 672 Query: 1120 SQLAYSVL 1143 SQL++ L Sbjct: 673 SQLSHQDL 680
>Q683C9:AUR2_ARATH Serine/threonine-protein kinase Aurora-2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 282 Score = 68.6 bits (166), Expect = 6e-11 Identities = 77/319 (24%), Positives = 123/319 (38%), Gaps = 2/319 (0%) Frame = +1 Query: 136 LYDAATGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYA 315 LY AA+ F + + +G G F VYL AR++ H+ Sbjct: 2 LYQAASEAAQKRWTTSDFDIGKPLGRGKFGHVYL----------AREKRSDHIVA--LKV 49 Query: 316 MKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHL 495 + K +Q + ++ E+ + S HPN+L L + + YL+ + Sbjct: 50 LFKAQLQQSQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKR---------VYLILEYAV 100 Query: 496 DGTLFDNAAVMQSRKEFYSVLDVLRIFQQI--CEGLKHMHSLDPPYAHNDVKPGNVLVTR 669 G L+ + E + V + + + C G KH+ H D+KP N+L+ Sbjct: 101 RGELYKELQKCKYFSERRAATYVASLARALIYCHG-KHV-------IHRDIKPENLLIGA 152 Query: 670 QKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDE 849 Q G+ +A DFG S N+ R+ L + PE+ + H D Sbjct: 153 Q-GELKIA---DFGWSVHTFNRRRTMCGTL------------DYLPPEMVESVEH---DA 193 Query: 850 RTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVT 1029 DIWSLG Y +YGV PFE I+ LK+P P P + ++ Sbjct: 194 SVDIWSLGILCYEFLYGVPPFE---AREHSETYKRIVQVDLKFP--PKPIVSSSAKDLIS 248 Query: 1030 WMLQPQPAMRPHINDILLH 1086 ML + R ++ +L H Sbjct: 249 QMLVKESTQRLALHKLLEH 267
>P07313:MYLK2_RABIT Myosin light chain kinase 2, skeletal/cardiac muscle - Oryctolagus| cuniculus (Rabbit) Length = 608 Score = 67.8 bits (164), Expect = 1e-10 Identities = 68/267 (25%), Positives = 116/267 (43%), Gaps = 2/267 (0%) Frame = +1 Query: 313 AMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVH 492 A K + Q+ + ++V EI V + NH NL+ L +A I + HE L Sbjct: 324 AAKVIKKQTPKDKEMVMLEIEVMNQLNHRNLIQL--YAAI-------ETPHEIVLFMEYI 374 Query: 493 LDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQ 672 G LF+ + +D + +QIC+G+ MH + H D+KP N+L Sbjct: 375 EGGELFERIV---DEDYHLTEVDTMVFVRQICDGILFMHKMR--VLHLDLKPENILCVNT 429 Query: 673 KGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDER 852 G L ++DFG +R + +E L++ E F +PE+ ++ I ++ Sbjct: 430 TGH--LVKIIDFGLARRY-----NPNEKLKVNFGTPE-----FLSPEV---VNYDQISDK 474 Query: 853 TDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTW 1032 TD+WSLG Y ++ G+SPF LG+ +++ + + D FV+ Sbjct: 475 TDMWSLGVITYMLLSGLSPF---LGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSN 531 Query: 1033 MLQPQPAMRPHINDILLH--VDKLVEK 1107 ++ + R L H ++ L EK Sbjct: 532 LIVKEQGARMSAAQCLAHPWLNNLAEK 558
>P38147:CHK1_YEAST Serine/threonine-protein kinase CHK1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 527 Score = 67.8 bits (164), Expect = 1e-10 Identities = 67/249 (26%), Positives = 109/249 (43%), Gaps = 4/249 (1%) Frame = +1 Query: 352 DLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD----NA 519 D+ KE + S HPN+L L+D + S + W ++ + G LFD + Sbjct: 61 DITKEVVLQSKCSKHPNVLRLIDCNV----SKEYMW-----IILEMADGGDLFDKIEPDV 111 Query: 520 AVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATL 699 V +FY FQQ+ + ++H ++ AH D+KP N+L+ + G LA Sbjct: 112 GVDSDVAQFY--------FQQLVSAINYLH-VECGVAHRDIKPENILLDKN-GNLKLA-- 159 Query: 700 MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCT 879 DFG + +Q R + LR+ + S P+ APE+ D RTDIWS+G Sbjct: 160 -DFGLA----SQFRRKDGTLRVS--MDQRGSPPYMAPEVLYSEEGYYAD-RTDIWSIGIL 211 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 L+ ++ G +P+E E+ + + L W + + +LQP P R Sbjct: 212 LFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHL--NLLRKILQPDPNKR 269 Query: 1060 PHINDILLH 1086 + + LH Sbjct: 270 VTLKALKLH 278
>Q7T6Y1:YR436_MIMIV Putative serine/threonine-protein kinase R436 - Mimivirus| Length = 276 Score = 67.4 bits (163), Expect = 1e-10 Identities = 68/271 (25%), Positives = 129/271 (47%), Gaps = 11/271 (4%) Frame = +1 Query: 298 GDGTYAMKKVLIQSREQLDLVKE----EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSH 465 G T ++KV+I+ + + KE +I + S+ NHPN++ + D+ + S+ Sbjct: 23 GTDTITLQKVVIKIYDDKNKSKESILRDIHIPSILNHPNIIKIKDY-------VEDLDSN 75 Query: 466 EAYLLFPVHLDGTL------FDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPY 627 + Y+++P ++D T+ D V K +Y ++ I Q+ + + +MH D Sbjct: 76 KMYVIYP-YIDNTISLRNLPVDKFDVTDLFKLYY----IIDILIQVVDAISYMH--DNNI 128 Query: 628 AHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRA 807 H D+KP N+L+ + L+DF S +Q+ + +R + F A Sbjct: 129 VHRDIKPDNILLNDK------VHLIDFDLS----DQLDNPKFPVRKGTIGTPN----FMA 174 Query: 808 PELWDCPSHADIDERTDIWSLGCTLYAIMYGVS-PFEYALGESGGSLQLAIMNAQLKWPQ 984 PE+W + D ++TDI+SLG T+Y ++ P++ + L+ I N + P+ Sbjct: 175 PEIWWKINQVDY-KKTDIYSLGITMYYLLNKRKLPYK---AKKYSELEYQIANHK---PK 227 Query: 985 LPSPPYPDALHKFVTWMLQPQPAMRPHINDI 1077 + + YP+ L K + ++ P RP I++I Sbjct: 228 ISNSGYPE-LDKLIMKIIDKDPQNRPTISEI 257
>Q6NU21:TAO1A_XENLA Serine/threonine-protein kinase TAO1-A - Xenopus laevis (African| clawed frog) Length = 1001 Score = 67.4 bits (163), Expect = 1e-10 Identities = 80/311 (25%), Positives = 126/311 (40%), Gaps = 1/311 (0%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDL 357 E+ F LR+IG G F VY HDAS+ SG QS E+ Sbjct: 25 EKLFSDLREIGHGSFGAVYFA--HDASTREVVAIKKMSYSGK----------QSNEKWQD 72 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 + +E++ HPN + + H A+L+ L G+ D +++ Sbjct: 73 IVKEVKFLQRIKHPNSIEYKGCYLR---------EHTAWLVMEYCL-GSASD---LLEVH 119 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 K+ +++ I +GL ++HS + H D+K GN+L+T + GQ LA DFGS+ Sbjct: 120 KKPLQEIEIAAITHGALQGLAYLHSHN--LIHRDIKAGNILLT-EPGQVKLA---DFGSA 173 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 A A P+ APE+ D + D+WSLG T + Sbjct: 174 SIASP--------------ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELA 219 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHIND 1074 P + ++ AQ + P L S + D FV LQ P RP ++ Sbjct: 220 ERKPPL-----FNMNAMSALYHIAQNESPTLQSNEWSDFFRNFVDSCLQKIPQDRPTSDE 274 Query: 1075 ILLHVDKLVEK 1107 +L ++ L+E+ Sbjct: 275 LLKNMFVLLER 285
>Q7TSC3:NEK5_MOUSE Serine/threonine-protein kinase Nek5 - Mus musculus (Mouse)| Length = 627 Score = 67.0 bits (162), Expect = 2e-10 Identities = 69/300 (23%), Positives = 122/300 (40%), Gaps = 2/300 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F +++ IGEG F VYL K+ SS +K++ + ++ K Sbjct: 4 FHLIKIIGEGTFGKVYLAKDKSESSHCV---------------IKEISLTKEKEAS--KN 46 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 E+ + + HPN++ + + +++ G L + + R Sbjct: 47 EVILLARMEHPNIVTFF---------SSFQENGRLFIVMEYCDGGDLMQR--IQRQRGVM 95 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 +S +L F QI GLKH+H D H D+K N+ +++ +A L DFG++R Sbjct: 96 FSEDQILCWFVQISLGLKHIH--DRKILHRDIKSQNIFLSKN---GMVAKLGDFGTARTL 150 Query: 727 RNQIRSRSEALRLQEWAAEHCSAP--FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 + + A+ C+ + +PE+ + + +TDIWSLGC LY + Sbjct: 151 NDSME-----------LAQTCAGTPYYLSPEICQ---NRPYNNKTDIWSLGCVLYELCTL 196 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PF ES L + Q + + SP + L + + + P RP + +L Sbjct: 197 KHPF-----ESNNFHHLVLKICQGRVAPI-SPHFSRDLQSLIPQLFRVSPQDRPSVTSLL 250
>Q39030:KPK19_ARATH Serine/threonine-protein kinase AtPK19 - Arabidopsis thaliana| (Mouse-ear cress) Length = 471 Score = 67.0 bits (162), Expect = 2e-10 Identities = 74/292 (25%), Positives = 117/292 (40%), Gaps = 1/292 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F VL+ +G+G F VY V++ D S YAMK + + D + E Sbjct: 140 FEVLKVVGQGAFGKVYQVRKKDTSE---------------IYAMKVM------RKDKIVE 178 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 + + ++L +DH I + YL+ G LF +E Sbjct: 179 KNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFRE- 237 Query: 547 YSVLDVLRIFQ-QICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 D+ R++ +I + H+H + H D+KP N+L+ L DFG ++ Sbjct: 238 ----DLARVYTAEIVSAVSHLH--EKGIMHRDLKPENILMDVDGH----VMLTDFGLAKE 287 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 RS S + + APE+ H D+ D WS+G LY ++ G Sbjct: 288 FEENTRSNSMC----------GTTEYMAPEIVRGKGH---DKAADWWSVGILLYEMLTGK 334 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 PF LG S G +Q I+ ++K PQ S + H + +LQ +P R Sbjct: 335 PPF---LG-SKGKIQQKIVKDKIKLPQFLS----NEAHALLKGLLQKEPERR 378
>A4IFM7:MYLK2_BOVIN Myosin light chain kinase 2, skeletal/cardiac muscle - Bos taurus| (Bovine) Length = 623 Score = 66.6 bits (161), Expect = 2e-10 Identities = 70/269 (26%), Positives = 118/269 (43%), Gaps = 4/269 (1%) Frame = +1 Query: 313 AMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVH 492 A K + Q+ + ++V EI V + NH NL+ L +A I + HE L Sbjct: 339 AAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQL--YAAI-------ETPHEIVLFMEYI 389 Query: 493 LDGTLFDNAAVMQSRKEFYSV--LDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVT 666 G LF+ E Y + +D + +QIC+G+ MH + H D+KP N+L Sbjct: 390 EGGELFERIV-----DEDYQLTEVDTMVFVRQICDGILFMHKMR--VLHLDLKPENILCV 442 Query: 667 RQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADID 846 G L ++DFG +R + +E L++ E F +PE+ ++ I Sbjct: 443 NTTGH--LVKIIDFGLARRY-----NPNEKLKVNFGTPE-----FLSPEV---VNYDQIS 487 Query: 847 ERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFV 1026 ++TD+WSLG Y ++ G+SPF LG+ ++++ + + D FV Sbjct: 488 DKTDMWSLGVITYMLLSGLSPF---LGDDDTETLNNVLSSNWYFDEETFEAVSDEAKDFV 544 Query: 1027 TWMLQPQPAMRPHINDILLH--VDKLVEK 1107 + ++ R L H ++ L EK Sbjct: 545 SNLIVKDQRARMSAAQCLAHPWLNNLAEK 573
>Q61RA2:CHK1_CAEBR Serine/threonine-protein kinase chk-1 - Caenorhabditis briggsae| Length = 493 Score = 66.6 bits (161), Expect = 2e-10 Identities = 70/262 (26%), Positives = 116/262 (44%), Gaps = 8/262 (3%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 +RV+R +GEG F V L+ +++P D AMKK+ I ++ + +++ Sbjct: 26 YRVIRTLGEGAFGEVLLI---------VNNKNP-----DMAVAMKKMQITTQANTNNIRK 71 Query: 367 EIRVS---SLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD-GTLFD----NAA 522 E + S H N + I +++ G + LF + D G LFD + Sbjct: 72 EFLIQQKLSKVGHDNFI-----RAIGMRTENG-----FHFLFLEYADGGELFDKIEPDHG 121 Query: 523 VMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLM 702 + + +FY F+Q+ EGLK++H D H D+KP N+L+T + + + Sbjct: 122 MPTAIAQFY--------FRQLIEGLKYIHDCD--IVHRDIKPENLLLT----TSHVLKIS 167 Query: 703 DFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTL 882 DFG + RN+ + R L + P+ APE+ C D+WS G L Sbjct: 168 DFGMATLYRNEGKERLLDLSCG-------TIPYAAPEV--CAGGKYRGPPIDVWSSGIVL 218 Query: 883 YAIMYGVSPFEYALGESGGSLQ 948 A++ G P++ A S LQ Sbjct: 219 IAMLTGELPWDRASDSSYAYLQ 240
>Q95ZQ4:AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-2 -| Caenorhabditis elegans Length = 626 Score = 66.6 bits (161), Expect = 2e-10 Identities = 79/289 (27%), Positives = 118/289 (40%), Gaps = 4/289 (1%) Frame = +1 Query: 232 YLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLV---KEEIRVSSLFNHPN 402 Y++KE + + H + A+K + Q + LD+V + EI+ SLF HP+ Sbjct: 87 YILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPH 146 Query: 403 LLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQ 582 ++ L V ST D +++ G LFD K + R FQQ Sbjct: 147 IIRLYQ-----VISTPSD----IFMIMEHVSGGELFDYIVKHGRLK----TAEARRFFQQ 193 Query: 583 ICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALR 762 I G+ + H H D+KP N+L+ Q + DFG S I + + LR Sbjct: 194 IISGVDYCHR--HMVVHRDLKPENLLLDEQNN----VKIADFGLSN-----IMTDGDFLR 242 Query: 763 LQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGG 939 C +P + APE+ +A + D+WS G LYA++ G PF+ E Sbjct: 243 TS------CGSPNYAAPEVISGKLYAGPE--VDVWSCGVILYALLCGTLPFD---DEHVP 291 Query: 940 SLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 SL I + P P + LH ML P R I D++ H Sbjct: 292 SLFRKIKSGVFPTPDFLERPIVNLLHH----MLCVDPMKRATIKDVIAH 336
>Q9H1R3:MYLK2_HUMAN Myosin light chain kinase 2, skeletal/cardiac muscle - Homo sapiens| (Human) Length = 596 Score = 66.2 bits (160), Expect = 3e-10 Identities = 67/267 (25%), Positives = 116/267 (43%), Gaps = 2/267 (0%) Frame = +1 Query: 313 AMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVH 492 A K + Q+ + ++V EI V + NH NL+ L +A I + HE L Sbjct: 312 AAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQL--YAAI-------ETPHEIVLFMEYI 362 Query: 493 LDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQ 672 G LF+ + +D + +QIC+G+ MH + H D+KP N+L Sbjct: 363 EGGELFERIV---DEDYHLTEVDTMVFVRQICDGILFMHKMR--VLHLDLKPENILCVNT 417 Query: 673 KGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDER 852 G L ++DFG +R + +E L++ E F +PE+ ++ I ++ Sbjct: 418 TGH--LVKIIDFGLARRY-----NPNEKLKVNFGTPE-----FLSPEV---VNYDQISDK 462 Query: 853 TDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTW 1032 TD+WS+G Y ++ G+SPF LG+ +++ + + D FV+ Sbjct: 463 TDMWSMGVITYMLLSGLSPF---LGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSN 519 Query: 1033 MLQPQPAMRPHINDILLH--VDKLVEK 1107 ++ R + L H ++ L EK Sbjct: 520 LIVKDQRARMNAAQCLAHPWLNNLAEK 546
>P11801:KPSH1_HUMAN Serine/threonine-protein kinase H1 - Homo sapiens (Human)| Length = 424 Score = 66.2 bits (160), Expect = 3e-10 Identities = 72/302 (23%), Positives = 125/302 (41%), Gaps = 1/302 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++ + IG G F+ V V EH A+ R P YA+K + + RE ++ + Sbjct: 97 KYDIKALIGRGSFSRVVRV-EHRAT------RQP--------YAIKMIETKYREGREVCE 141 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E+RV H N++ L++ V TQ Y++ + G LFD S Sbjct: 142 SELRVLRRVRHANIIQLVE-----VFETQ----ERVYMVMELATGGELFDRIIAKGS--- 189 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 ++ D R+ Q + +G++++H+L H D+KP N+L G + DFG + Sbjct: 190 -FTERDATRVLQMVLDGVRYLHALG--ITHRDLKPENLLYYHP-GTDSKIIITDFGLA-- 243 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 R + + ++ C P + APE+ + + D+W+LG Y ++ G Sbjct: 244 ---SARKKGDDCLMKTT----CGTPEYIAPEVLVRKPYTN---SVDMWALGVIAYILLSG 293 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PFE ++ L I+ + + P P + F+ +L P R L Sbjct: 294 TMPFE---DDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQAL 350 Query: 1081 LH 1086 H Sbjct: 351 RH 352
>Q0V7M1:KPSH1_BOVIN Serine/threonine-protein kinase H1 - Bos taurus (Bovine)| Length = 424 Score = 66.2 bits (160), Expect = 3e-10 Identities = 72/302 (23%), Positives = 125/302 (41%), Gaps = 1/302 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++ + IG G F+ V V EH A+ R P YA+K + + RE ++ + Sbjct: 97 KYDIKALIGRGSFSRVVRV-EHRAT------RQP--------YAIKMIETKYREGREVCE 141 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E+RV H N++ L++ V TQ Y++ + G LFD S Sbjct: 142 SELRVLRRVRHANIIQLVE-----VFETQ----ERVYMVMELATGGELFDRIIAKGS--- 189 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 ++ D R+ Q + +G++++H+L H D+KP N+L G + DFG + Sbjct: 190 -FTERDATRVLQMVLDGVRYLHALG--ITHRDLKPENLLYYHP-GTDSKIIITDFGLA-- 243 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 R + + ++ C P + APE+ + + D+W+LG Y ++ G Sbjct: 244 ---SARKKGDDCLMKTT----CGTPEYIAPEVLVRKPYTN---SVDMWALGVIAYILLSG 293 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PFE ++ L I+ + + P P + F+ +L P R L Sbjct: 294 TMPFE---DDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQAL 350 Query: 1081 LH 1086 H Sbjct: 351 RH 352
>Q8BWQ5:DCLK3_MOUSE Serine/threonine-protein kinase DCLK3 - Mus musculus (Mouse)| Length = 619 Score = 66.2 bits (160), Expect = 3e-10 Identities = 64/247 (25%), Positives = 104/247 (42%), Gaps = 2/247 (0%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKV-LIQSREQLD 354 E+ + + IG+G FA V + + YAMK + Q + + D Sbjct: 340 EKHYDIGGVIGDGNFATVKECRHRETKQ---------------AYAMKMIDKSQLKGKED 384 Query: 355 LVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 +V EI + +HPN++ L H + ++ E YL+ G LFD A++++ Sbjct: 385 IVDSEILIIQSLSHPNIVKL--HEVYETEA-------EIYLIMEYVQGGDLFD--AIVEN 433 Query: 535 RKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGS 714 K + + + +C+ L HMH D H DVKP N+LV R + ++ L DFG Sbjct: 434 VK--FPEPEAAVMITDLCKALVHMH--DKNIVHRDVKPENLLVQRNEDKSITLKLADFGL 489 Query: 715 SRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAI 891 ++ I + C P + APE+ S D+W+ G LY + Sbjct: 490 AKYVVRPIFT-------------VCGTPTYVAPEIL---SEKGYGLEVDMWAAGVILYIL 533 Query: 892 MYGVSPF 912 + G PF Sbjct: 534 LCGFPPF 540
>Q9M077:AUR1_ARATH Serine/threonine-protein kinase Aurora-1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 294 Score = 66.2 bits (160), Expect = 3e-10 Identities = 80/306 (26%), Positives = 126/306 (41%), Gaps = 6/306 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F + + +G G F VYL AR++ +HV KVL +S+ Q V+ Sbjct: 31 FDIGKPLGRGKFGHVYL----------AREKRSNHV------VALKVLFKSQLQQSQVEH 74 Query: 367 EIR----VSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 ++R + S HPN+L L + + YL+ G L+ + + Sbjct: 75 QLRREVEIQSHLRHPNILRLYGYFYDQKR---------VYLILEYAARGELYKDLQKCKY 125 Query: 535 RKEFYSVLDVLRIFQQI--CEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 E + V + + + C G KH+ H D+KP N+L+ Q G+ +A DF Sbjct: 126 FSERRAATYVASLARALIYCHG-KHV-------IHRDIKPENLLIGAQ-GELKIA---DF 173 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYA 888 G S N+ R+ L + PE+ + H D DIWSLG Y Sbjct: 174 GWSVHTFNRRRTMCGTL------------DYLPPEMVESVEH---DASVDIWSLGILCYE 218 Query: 889 IMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHI 1068 +YGV PFE A+ S I+ LK+P P P + ++ ML + + R + Sbjct: 219 FLYGVPPFE-AMEHS--DTYRRIVQVDLKFP--PKPIISASAKDLISQMLVKESSQRLPL 273 Query: 1069 NDILLH 1086 + +L H Sbjct: 274 HKLLEH 279
>Q7L7X3:TAOK1_HUMAN Serine/threonine-protein kinase TAO1 - Homo sapiens (Human)| Length = 1001 Score = 65.9 bits (159), Expect = 4e-10 Identities = 80/314 (25%), Positives = 126/314 (40%), Gaps = 4/314 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E+ F LR+IG G F VY ARD + V A+KK+ QS E+ Sbjct: 25 EKLFTDLREIGHGSFGAVYF----------ARDVRTNEV-----VAIKKMSYSGKQSTEK 69 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E++ HPN + + H A+L+ ++ L + ++ Sbjct: 70 WQDIIKEVKFLQRIKHPNSIEYKGCYL---------REHTAWLV----MEYCLGSASDLL 116 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + K+ +++ I +GL ++HS H D+K GN+L+T + GQ LA DF Sbjct: 117 EVHKKPLQEVEIAAITHGALQGLAYLHS--HTMIHRDIKAGNILLT-EPGQVKLA---DF 170 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLY 885 GS+ A A P+ APE+ D + D+WSLG T Sbjct: 171 GSASMASP--------------ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCI 216 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + P + ++ AQ + P L S + D FV LQ P RP Sbjct: 217 ELAERKPPL-----FNMNAMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPT 271 Query: 1066 INDILLHVDKLVEK 1107 ++L H+ L E+ Sbjct: 272 SEELLKHIFVLRER 285
>Q5SUV5:SGK85_MOUSE Uncharacterized serine/threonine-protein kinase SgK085 - Mus musculus| (Mouse) Length = 386 Score = 65.9 bits (159), Expect = 4e-10 Identities = 66/263 (25%), Positives = 113/263 (42%), Gaps = 5/263 (1%) Frame = +1 Query: 313 AMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLD-----HAIIAVKSTQGDWSHEAYL 477 A K + + + + VK EI V + +H NL+ L D H II V +G Sbjct: 134 AAKIIKTRGAKDKEDVKNEISVMNQLDHVNLIQLYDAFESKHDIILVMDVEG-------- 185 Query: 478 LFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNV 657 G LFD + LD + +QICEG+++MH + H D+KP N+ Sbjct: 186 -------GELFDRIIDENCN---LTELDTILFMKQICEGIRYMHQMY--ILHLDLKPENI 233 Query: 658 LVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHA 837 L + A ++DFG +R + + E L++ E F APE+ ++ Sbjct: 234 LCVNR--DAKQIKIIDFGLARRYKPR-----EKLKVNFGTPE-----FLAPEV---VNYD 278 Query: 838 DIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALH 1017 + TD+WS+G Y ++ G+SPF LG++ I+ + + Sbjct: 279 FVSFSTDMWSVGVITYMLLSGLSPF---LGDNDAETLTNILACRWDLEDEEFQDISEEAK 335 Query: 1018 KFVTWMLQPQPAMRPHINDILLH 1086 +F++ +L + + R ++ L H Sbjct: 336 EFISKLLIKEKSWRISASEALKH 358
>Q86YV6:SGK85_HUMAN Uncharacterized serine/threonine-protein kinase SgK085 - Homo sapiens| (Human) Length = 388 Score = 65.9 bits (159), Expect = 4e-10 Identities = 67/260 (25%), Positives = 117/260 (45%), Gaps = 2/260 (0%) Frame = +1 Query: 313 AMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVH 492 A K + + + + VK EI V + +H NL+ L D A +S ++ L+ Sbjct: 133 AAKIIKTRGMKDKEEVKNEISVMNQLDHANLIQLYD----AFES-----KNDIVLVMEYV 183 Query: 493 LDGTLFDNAAVMQSRKEFYSV--LDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVT 666 G LFD E Y++ LD + +QICEG++HMH + H D+KP N+L Sbjct: 184 DGGELFDRII-----DESYNLTELDTILFMKQICEGIRHMHQM--YILHLDLKPENILCV 236 Query: 667 RQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADID 846 + A ++DFG +R + + E L++ E F APE+ ++ + Sbjct: 237 NR--DAKQIKIIDFGLARRYKPR-----EKLKVNFGTPE-----FLAPEV---VNYDFVS 281 Query: 847 ERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFV 1026 TD+WS+G Y ++ G+SPF LG++ I+ + + +F+ Sbjct: 282 FPTDMWSVGVIAYMLLSGLSPF---LGDNDAETLNNILACRWDLEDEEFQDISEEAKEFI 338 Query: 1027 TWMLQPQPAMRPHINDILLH 1086 + +L + + R ++ L H Sbjct: 339 SKLLIKEKSWRISASEALKH 358
>P51954:NEK1_MOUSE Serine/threonine-protein kinase Nek1 - Mus musculus (Mouse)| Length = 1203 Score = 65.9 bits (159), Expect = 4e-10 Identities = 75/310 (24%), Positives = 127/310 (40%), Gaps = 5/310 (1%) Frame = +1 Query: 196 LRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ--SREQLDLVKEE 369 L++IGEG F LVK + RH Y +K++ I S ++ + E Sbjct: 7 LQKIGEGSFGKAVLVKSTEDG------RH---------YVIKEINISRMSDKERQESRRE 51 Query: 370 IRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFY 549 + V + HPN++ + + + Y++ G LF + + + Sbjct: 52 VAVLANMKHPNIVQYKESF---------EENGSLYIVMDYCEGGDLFKR--INAQKGALF 100 Query: 550 SVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPAR 729 +L F QIC LKH+H D H D+K N+ +T+ L DFG +R Sbjct: 101 QEDQILDWFVQICLALKHVH--DRKILHRDIKSQNIFLTKDG----TVQLGDFGIARVLN 154 Query: 730 NQIRSRSEALRLQEWAAEHCSAPFR-APELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 + + E A P+ +PE+ + + + ++DIW+LGC LY + Sbjct: 155 STV----------ELARTCIGTPYYLSPEICE---NKPYNNKSDIWALGCVLYELCTLKH 201 Query: 907 PFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILL- 1083 F E+G L + +P + SP Y L ++ + + P RP +N IL Sbjct: 202 AF-----EAGNMKNLVLKIISGSFPPV-SPHYSYDLRSLLSQLFKRNPRDRPSVNSILEK 255 Query: 1084 -HVDKLVEKY 1110 + K +EK+ Sbjct: 256 GFIAKRIEKF 265
>O14299:WIS4_SCHPO MAP kinase kinase kinase wis4 - Schizosaccharomyces pombe (Fission| yeast) Length = 1401 Score = 65.5 bits (158), Expect = 5e-10 Identities = 71/267 (26%), Positives = 110/267 (41%), Gaps = 9/267 (3%) Frame = +1 Query: 313 AMKKVLIQS----REQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLL 480 A+K++ +Q R +D + E+ V NHPN++ + K Y+ Sbjct: 1064 AVKEIKLQDSRTFRSTVDQIHNEMTVLERLNHPNVVTYYGVEVHREK---------VYIF 1114 Query: 481 FPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVL 660 G+L D A R E +VL V + Q+ EGL ++HS H D+KP N+L Sbjct: 1115 MEFCQGGSLADLLA--HGRIEDENVLKVYVV--QLLEGLAYIHSQH--ILHRDIKPANIL 1168 Query: 661 VTRQKGQAPLATLMDFGS----SRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCP 828 + + + DFGS S P ++R LQ A + + APE+ Sbjct: 1169 LDHRG----MIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAG---TPMYMAPEIILGT 1221 Query: 829 SHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPD 1008 D DIWSLGC + +M G +P+ E +A M+ P +P Sbjct: 1222 KKGDFGAM-DIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHT----PSIPQNEKIS 1276 Query: 1009 ALHK-FVTWMLQPQPAMRPHINDILLH 1086 +L + F+ + P RP D+L H Sbjct: 1277 SLARDFIEQCFERDPEQRPRAVDLLTH 1303
>P25323:MYLK_DICDI Myosin light chain kinase - Dictyostelium discoideum (Slime mold)| Length = 295 Score = 65.5 bits (158), Expect = 5e-10 Identities = 67/273 (24%), Positives = 116/273 (42%), Gaps = 4/273 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDL 357 E+ + ++G G F+ VYL + YA+K V+ +S D Sbjct: 5 EKIYEFKEELGRGAFSIVYLGENKQTKQ---------------RYAIK-VINKSELGKDY 48 Query: 358 ---VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 +K E+ + NHPN IIA+K D + YL+ + G LFD Sbjct: 49 EKNLKMEVDILKKVNHPN--------IIALKELF-DTPEKLYLVMELVTGGELFDKIV-- 97 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 K YS D + ++I + ++H L+ H D+KP N+L+ ++ +A + DF Sbjct: 98 --EKGSYSEADAANLVKKIVSAVGYLHGLN--IVHRDLKPENLLLKSKENHLEVA-IADF 152 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLY 885 G S+ + ++ C P + APE+ + + D+ D+WS+G Y Sbjct: 153 GLSKIIGQTLVMQTA-----------CGTPSYVAPEVLNATGY---DKEVDMWSIGVITY 198 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQ 984 ++ G PF G++ + IM A ++P+ Sbjct: 199 ILLCGFPPF---YGDTVPEIFEQIMEANYEFPE 228
>Q91YA2:KPSH1_MOUSE Serine/threonine-protein kinase H1 - Mus musculus (Mouse)| Length = 424 Score = 65.5 bits (158), Expect = 5e-10 Identities = 72/302 (23%), Positives = 125/302 (41%), Gaps = 1/302 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++ + IG G F+ V V EH A+ R P YA+K + + RE ++ + Sbjct: 97 KYDIKALIGRGSFSRVVRV-EHRAT------RQP--------YAIKMIETKYREGREVCE 141 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E+RV H N++ L++ V TQ Y++ + G LFD S Sbjct: 142 SELRVLRRVRHANIIQLVE-----VFETQ----ERVYMVMELATGGELFDRIIAKGS--- 189 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 ++ D R+ Q + +G++++H+L H D+KP N+L G + DFG + Sbjct: 190 -FTERDATRVLQMVLDGVRYLHALG--ITHRDLKPENLLYYHP-GTDSKIIITDFGLA-- 243 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 R + + ++ C P + APE+ + + D+W+LG Y ++ G Sbjct: 244 ---SARKKGDDCLMKTT----CGTPEYIAPEVLVRKPYTN---SVDMWALGVIAYILLSG 293 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PFE ++ L I+ + + P P + F+ +L P R L Sbjct: 294 TMPFE---DDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQAL 350 Query: 1081 LH 1086 H Sbjct: 351 RH 352
>O88664:TAOK1_RAT Serine/threonine-protein kinase TAO1 - Rattus norvegicus (Rat)| Length = 1001 Score = 65.1 bits (157), Expect = 7e-10 Identities = 80/314 (25%), Positives = 126/314 (40%), Gaps = 4/314 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E+ F LR+IG G F VY ARD + V A+KK+ QS E+ Sbjct: 25 EKLFTDLREIGHGSFGAVYF----------ARDVRTNEV-----VAIKKMSYSGKQSTEK 69 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E++ HPN + + H A+L+ ++ L + ++ Sbjct: 70 WQDIIKEVKFLQRIKHPNSIEYKGCYL---------REHTAWLV----MEYCLGSASDLL 116 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + K+ +++ I +GL ++HS H D+K GN+L+T + GQ LA DF Sbjct: 117 EVHKKPLQEVEIAAITHGALQGLAYLHS--HTMIHRDIKAGNILLT-EPGQVKLA---DF 170 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLY 885 GS+ A A P+ APE+ D + D+WSLG T Sbjct: 171 GSASMASP--------------ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCI 216 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + P + ++ AQ + P L S + D FV LQ P RP Sbjct: 217 ELAERKPPL-----FNMNAMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPT 271 Query: 1066 INDILLHVDKLVEK 1107 ++L H+ L E+ Sbjct: 272 SEELLKHMFVLRER 285
>Q5F2E8:TAOK1_MOUSE Serine/threonine-protein kinase TAO1 - Mus musculus (Mouse)| Length = 1001 Score = 65.1 bits (157), Expect = 7e-10 Identities = 80/314 (25%), Positives = 126/314 (40%), Gaps = 4/314 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E+ F LR+IG G F VY ARD + V A+KK+ QS E+ Sbjct: 25 EKLFTDLREIGHGSFGAVYF----------ARDVRTNEV-----VAIKKMSYSGKQSTEK 69 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E++ HPN + + H A+L+ ++ L + ++ Sbjct: 70 WQDIIKEVKFLQRIKHPNSIEYKGCYL---------REHTAWLV----MEYCLGSASDLL 116 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + K+ +++ I +GL ++HS H D+K GN+L+T + GQ LA DF Sbjct: 117 EVHKKPLQEVEIAAITHGALQGLAYLHS--HTMIHRDIKAGNILLT-EPGQVKLA---DF 170 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLY 885 GS+ A A P+ APE+ D + D+WSLG T Sbjct: 171 GSASMASP--------------ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCI 216 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + P + ++ AQ + P L S + D FV LQ P RP Sbjct: 217 ELAERKPPL-----FNMNAMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPT 271 Query: 1066 INDILLHVDKLVEK 1107 ++L H+ L E+ Sbjct: 272 SEELLKHMFVLRER 285
>P42818:KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 - Arabidopsis thaliana| (Mouse-ear cress) Length = 465 Score = 65.1 bits (157), Expect = 7e-10 Identities = 72/292 (24%), Positives = 117/292 (40%), Gaps = 1/292 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F V++ +G+G F VY V++ + S YAMK + + D + E Sbjct: 134 FEVMKVVGKGAFGKVYQVRKKETSE---------------IYAMKVM------RKDHIME 172 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 + + ++L +DH I + YL+ G LF +E Sbjct: 173 KNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFRE- 231 Query: 547 YSVLDVLRIFQ-QICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 D+ R++ +I + H+H + H D+KP N+L+ L DFG ++ Sbjct: 232 ----DLARVYTAEIVSAVSHLH--EKGIMHRDLKPENILMDTDGH----VMLTDFGLAKE 281 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 RS S + + APE+ H D+ D WS+G LY ++ G Sbjct: 282 FEENTRSNSMC----------GTTEYMAPEIVRGKGH---DKAADWWSVGILLYEMLTGK 328 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 PF LG S G +Q I+ ++K PQ S + H + +LQ +P R Sbjct: 329 PPF---LG-SKGKIQQKIVKDKIKLPQFLS----NEAHAILKGLLQKEPERR 372
>P11730:KCC2G_RAT Calcium/calmodulin-dependent protein kinase type II gamma chain -| Rattus norvegicus (Rat) Length = 527 Score = 65.1 bits (157), Expect = 7e-10 Identities = 61/243 (25%), Positives = 103/243 (42%), Gaps = 1/243 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVY-LVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 +++ ++G+G F+ V VK+ AA+ KK+ + ++L+ Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAK-----------IINTKKLSARDHQKLE--- 59 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E R+ L HPN++ L D S + H YL+F + G LF++ +E Sbjct: 60 REARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTGGELFEDIVA----RE 106 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 +YS D QI E + H+H D H D+KP N+L+ K + L DFG + Sbjct: 107 YYSEADASHCIHQILESVNHIHQHD--IVHRDLKPENLLLA-SKCKGAAVKLADFGLAIE 163 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 + + Q W + + +PE+ + + DIW+ G LY ++ G Sbjct: 164 VQGE---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVDIWACGVILYILLVGY 211 Query: 904 SPF 912 PF Sbjct: 212 PPF 214
>Q923T9:KCC2G_MOUSE Calcium/calmodulin-dependent protein kinase type II gamma chain -| Mus musculus (Mouse) Length = 529 Score = 65.1 bits (157), Expect = 7e-10 Identities = 61/243 (25%), Positives = 103/243 (42%), Gaps = 1/243 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVY-LVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 +++ ++G+G F+ V VK+ AA+ KK+ + ++L+ Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAK-----------IINTKKLSARDHQKLE--- 59 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E R+ L HPN++ L D S + H YL+F + G LF++ +E Sbjct: 60 REARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTGGELFEDIVA----RE 106 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 +YS D QI E + H+H D H D+KP N+L+ K + L DFG + Sbjct: 107 YYSEADASHCIHQILESVNHIHQHD--IVHRDLKPENLLLA-SKCKGAAVKLADFGLAIE 163 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 + + Q W + + +PE+ + + DIW+ G LY ++ G Sbjct: 164 VQGE---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVDIWACGVILYILLVGY 211 Query: 904 SPF 912 PF Sbjct: 212 PPF 214
>Q13555:KCC2G_HUMAN Calcium/calmodulin-dependent protein kinase type II gamma chain -| Homo sapiens (Human) Length = 558 Score = 65.1 bits (157), Expect = 7e-10 Identities = 61/243 (25%), Positives = 103/243 (42%), Gaps = 1/243 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVY-LVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 +++ ++G+G F+ V VK+ AA+ KK+ + ++L+ Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAK-----------IINTKKLSARDHQKLE--- 59 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E R+ L HPN++ L D S + H YL+F + G LF++ +E Sbjct: 60 REARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTGGELFEDIVA----RE 106 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 +YS D QI E + H+H D H D+KP N+L+ K + L DFG + Sbjct: 107 YYSEADASHCIHQILESVNHIHQHD--IVHRDLKPENLLLA-SKCKGAAVKLADFGLAIE 163 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 + + Q W + + +PE+ + + DIW+ G LY ++ G Sbjct: 164 VQGE---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVDIWACGVILYILLVGY 211 Query: 904 SPF 912 PF Sbjct: 212 PPF 214
>Q7ZYJ0:TAO1B_XENLA Serine/threonine-protein kinase TAO1-B - Xenopus laevis (African| clawed frog) Length = 1001 Score = 64.7 bits (156), Expect = 8e-10 Identities = 75/310 (24%), Positives = 124/310 (40%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDL 357 E+ F LR+IG G F VY HDA + SG QS E+ Sbjct: 25 EKLFSDLREIGHGSFGAVYFA--HDARTSEVVAIKKMSYSGK----------QSNEKWQD 72 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 + +E++ HPN + + H A+L+ ++ L + +++ Sbjct: 73 IIKEVKFLQRIQHPNSIEYKGCYL---------REHTAWLV----MEYCLGSASDLLEVH 119 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 K+ +++ I +GL ++HS + H D+K GN+L+T + GQ LA DFGS+ Sbjct: 120 KKPLQEIEIAAITHGALQGLAYLHSHN--LIHRDIKAGNILLT-EPGQVKLA---DFGSA 173 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 + + + + W APE+ D + D+WSLG T + Sbjct: 174 ----SIVSPANSFVGTPYW---------MAPEVILAMDEGQYDGKVDVWSLGITCVELAE 220 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDI 1077 P + ++ AQ + P L S + D FV L P RP +++ Sbjct: 221 RKPPL-----FNMNAMSALYHIAQNESPTLQSTEWSDYFRNFVDSCLHKIPQDRPTSDEL 275 Query: 1078 LLHVDKLVEK 1107 L H+ L E+ Sbjct: 276 LKHMFVLRER 285
>O15075:DCLK1_HUMAN Serine/threonine-protein kinase DCLK1 - Homo sapiens (Human)| Length = 740 Score = 64.7 bits (156), Expect = 8e-10 Identities = 68/286 (23%), Positives = 117/286 (40%), Gaps = 1/286 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R++V R IG+G FA V E + + A +KK + +E + ++ Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALK------------IIKKSKCRGKEHM--IQ 434 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E+ + HPN++ L++ D E YL+ + G LFD A+ + K Sbjct: 435 NEVSILRRVKHPNIVLLIEEM---------DVPTELYLVMELVKGGDLFD--AITSTNK- 482 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 Y+ D + + +K++HSL+ H D+KP N+LV + + L DFG + Sbjct: 483 -YTERDASGMLYNLASAIKYLHSLN--IVHRDIKPENLLVYEHQDGSKSLKLGDFGLATI 539 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 + + C P + APE+ + + DIW+ G Y ++ G Sbjct: 540 VDGPLYT-------------VCGTPTYVAPEI---IAETGYGLKVDIWAAGVITYILLCG 583 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWML 1038 PF G+ L I+ Q+ +P D+ + +T ML Sbjct: 584 FPPFR-GSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMML 628
>Q5RAJ5:STK36_PONPY Serine/threonine-protein kinase 36 - Pongo pygmaeus (Orangutan)| Length = 1315 Score = 64.3 bits (155), Expect = 1e-09 Identities = 76/309 (24%), Positives = 122/309 (39%), Gaps = 8/309 (2%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++ VL IGEG F VY + ++ A P L +S ++L ++ Sbjct: 3 KYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-------------LGRSEKELRNLQ 49 Query: 364 EEIRVSSLFNHPNLLPLLD------HAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAV 525 EI + HPN++ +LD ++ +G+ LL + DG L ++ Sbjct: 50 REIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGE------LLQILEDDGKLPED--- 100 Query: 526 MQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMD 705 V I Q+ L ++HS H D+KP N+L+ + G L D Sbjct: 101 -----------QVQAIAAQLVSALYYLHS--HRILHRDMKPQNILLAKGGG----IKLCD 143 Query: 706 FGSSRP--ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCT 879 FG +R + + + L + +PEL + D D+WS+GC Sbjct: 144 FGFARAMSTNTMVLTSIKGTPL-----------YMSPELVE---ERPYDHTADLWSVGCI 189 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 LY + G PF YA S L I+ ++WP SP + + F+ +L P R Sbjct: 190 LYELAVGTPPF-YA--TSIFQLVSLILKDPVRWPSTISPCFKN----FLQGLLTKDPRQR 242 Query: 1060 PHINDILLH 1086 D+L H Sbjct: 243 LSWPDLLYH 251
>P32562:CDC5_YEAST Cell cycle serine/threonine-protein kinase CDC5/MSD2 - Saccharomyces| cerevisiae (Baker's yeast) Length = 705 Score = 64.3 bits (155), Expect = 1e-09 Identities = 68/296 (22%), Positives = 118/296 (39%), Gaps = 1/296 (0%) Frame = +1 Query: 205 IGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSS 384 +GEGGFA + +K+ AA+ + K I+S + + EI++ Sbjct: 88 LGEGGFARCFQIKDDSGEIFAAK-------------TVAKASIKSEKTRKKLLSEIQIHK 134 Query: 385 LFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDV 564 +HPN++ +D + Y+L + +G+L + + R++ + +V Sbjct: 135 SMSHPNIVQFIDCF---------EDDSNVYILLEICPNGSLME----LLKRRKVLTEPEV 181 Query: 565 LRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRS 744 QIC +K+MHS H D+K GN+ + DFG + N+ Sbjct: 182 RFFTTQICGAIKYMHSRR--VIHRDLKLGNIFFDSNYN----LKIGDFGLAAVLANESER 235 Query: 745 RSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYA 921 + C P + APE+ H+ DIWSLG LYA++ G PF+ Sbjct: 236 KYTI----------CGTPNYIAPEVL-MGKHSGHSFEVDIWSLGVMLYALLIGKPPFQ-- 282 Query: 922 LGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLHV 1089 ++ I +P+ P D + +L P RP + +I+ +V Sbjct: 283 -ARDVNTIYERIKCRDFSFPR--DKPISDEGKILIRDILSLDPIERPSLTEIMDYV 335
>Q9HFF4:PPK1_SCHPO Serine/threonine-protein kinase ppk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1023 Score = 63.9 bits (154), Expect = 1e-09 Identities = 66/239 (27%), Positives = 104/239 (43%), Gaps = 7/239 (2%) Frame = +1 Query: 391 NHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLR 570 NHP+++ LD VK+ H ++ G LFD ++ R+ SV R Sbjct: 556 NHPHIVKYLDF----VKT-----KHHFGIVLDYVNGGELFDY--ILARRRLEDSV--ACR 602 Query: 571 IFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPAR--NQIRS 744 +F Q+ G+ ++HS H D+K N+L+ + + DFG + N + Sbjct: 603 LFAQLISGVAYLHSRG--VVHRDLKLENILLDTNRN----IVIADFGFATTFGHFNTLSE 656 Query: 745 RSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE-- 915 S + + C +P + APEL +C S + DIWS G LYA++ G PF+ Sbjct: 657 HSLPTEKPDLFSTSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPFDDD 716 Query: 916 --YALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 GE+ L I + L +P+ D L K +L P PA R ++ I+ H Sbjct: 717 PHNPNGENVPRLYRYICSTPLIFPEFFKSKARDILKK----ILVPDPAKRVRMSAIMNH 771
>P33973:PKN1_MYXXA Serine/threonine-protein kinase pkn1 - Myxococcus xanthus| Length = 693 Score = 63.9 bits (154), Expect = 1e-09 Identities = 74/277 (26%), Positives = 114/277 (41%), Gaps = 4/277 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKV---LIQSREQLDL 357 FR++R++G GG VYL HVS A+K + L E + Sbjct: 59 FRLVRRLGRGGMGAVYL---------------GEHVSIGSRVAVKVLHAHLTMYPELVQR 103 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 E R +L H N++ + D D + L LDG +A + + Sbjct: 104 FHAEARAVNLIGHENIVSIFDM----------DATPPRPYLIMEFLDGAPL--SAWVGTP 151 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 +V+ VL Q+C+ L+ H+ H D+KP N+ + R+ G AP ++DFG Sbjct: 152 LAAGAVVSVL---SQVCDALQAAHARG--IVHRDLKPDNIFLVRRNGNAPFVKVLDFG-- 204 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 I ++A Q A P + APE +D R D+++LG Y ++ Sbjct: 205 ------IAKLADAHMPQTHAGIIVGTPEYMAPEQ---SLGRGVDGRADLYALGVIAYQLL 255 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYP 1005 G PF + G + QL + QL+ P PS YP Sbjct: 256 TGRLPF----NDEGLAAQL--VAHQLRPPPPPSSVYP 286
>Q96PY6:NEK1_HUMAN Serine/threonine-protein kinase Nek1 - Homo sapiens (Human)| Length = 1258 Score = 63.9 bits (154), Expect = 1e-09 Identities = 81/353 (22%), Positives = 147/353 (41%), Gaps = 5/353 (1%) Frame = +1 Query: 196 LRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ--SREQLDLVKEE 369 L++IGEG F LVK S++ R Y +K++ I S ++ + + E Sbjct: 7 LQKIGEGSFGKAILVK----STEDGRQ-----------YVIKEINISRMSSKEREESRRE 51 Query: 370 IRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFY 549 + V + HPN++ + + + Y++ G LF + + + Sbjct: 52 VAVLANMKHPNIVQYRESF---------EENGSLYIVMDYCEGGDLFKR--INAQKGVLF 100 Query: 550 SVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPAR 729 +L F QIC LKH+H D H D+K N+ +T+ L DFG +R Sbjct: 101 QEDQILDWFVQICLALKHVH--DRKILHRDIKSQNIFLTKDG----TVQLGDFGIARVLN 154 Query: 730 NQIRSRSEALRLQEWAAEHCSAPFR-APELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 + + E A P+ +PE+ + + + ++DIW+LGC LY + Sbjct: 155 STV----------ELARTCIGTPYYLSPEICE---NKPYNNKSDIWALGCVLYELCTLKH 201 Query: 907 PFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILL- 1083 F E+G L + +P + S Y L V+ + + P RP +N IL Sbjct: 202 AF-----EAGSMKNLVLKIISGSFPPV-SLHYSYDLRSLVSQLFKRNPRDRPSVNSILEK 255 Query: 1084 -HVDKLVEKYSP*SQLAYSVLTCFFFIRLQREHGVRPML*AFSSFGIGTVSIL 1239 + K +EK+ L+ ++ F ++ + G +P+ + G ++S++ Sbjct: 256 GFIAKRIEKF-----LSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSISVM 303
>Q9LDI3:CPK24_ARATH CBL-interacting serine/threonine-protein kinase 24 - Arabidopsis| thaliana (Mouse-ear cress) Length = 446 Score = 63.9 bits (154), Expect = 1e-09 Identities = 76/300 (25%), Positives = 115/300 (38%), Gaps = 2/300 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++ V R IGEG FA V + D + A M K I +D +K Sbjct: 10 KYEVGRTIGEGTFAKVKFARNTDTGDNVA------------IKIMAKSTILKNRMVDQIK 57 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 EI + + HPN++ L + ++A S + Y++ G LFD +E Sbjct: 58 REISIMKIVRHPNIVRLYE--VLASPS-------KIYIVLEFVTGGELFDRIVHKGRLEE 108 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 S + FQQ+ + + H H H D+KP N+L+ + DFG S Sbjct: 109 SES----RKYFQQLVDAVAHCHCKG--VYHRDLKPENLLLDTNGN----LKVSDFGLSAL 158 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 + + E LR C P + APE+ + DIWS G L+ I+ G Sbjct: 159 PQEGV----ELLRTT------CGTPNYVAPEVLSGQGYDG--SAADIWSCGVILFVILAG 206 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKF-VTWMLQPQPAMRPHINDI 1077 PF L + ++ + PP+ A KF + +L P P R I I Sbjct: 207 YLPF--------SETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPNPKTRIQIQGI 258
>Q9U1Y5:CHK2_CAEEL Serine/threonine-protein kinase chk-2 - Caenorhabditis elegans| Length = 476 Score = 63.9 bits (154), Expect = 1e-09 Identities = 66/298 (22%), Positives = 126/298 (42%), Gaps = 6/298 (2%) Frame = +1 Query: 205 IGEGGFAFVYL-VKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVS 381 +G+GGF V L K+ D S A + + + + + ++R+ ++ E+ V Sbjct: 176 LGKGGFGKVLLGYKKSDRSVVAIKQLNTQFST-----RCSRAIAKTRD----IRNEVEVM 226 Query: 382 SLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLD 561 +HPN++ + D +A S Y++ G F V+ S+ + + Sbjct: 227 KKLSHPNIVAIYDWITVAKYS---------YMVIEYVGGGEFFSK--VVDSKYNRMGLGE 275 Query: 562 VLRIFQ--QICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQ 735 L + Q+ + + ++HS+ H D+KP N+L + K + + L DFG ++ + N+ Sbjct: 276 SLGKYFAFQLIDAILYLHSVG--ICHRDIKPENILCS-DKAERCILKLTDFGMAKNSVNR 332 Query: 736 IRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPF 912 +++R C P + APE+ + + DIWSLGC L+ G PF Sbjct: 333 MKTR-------------CGTPSYNAPEIV-ANEGVEYTPKVDIWSLGCVLFITFSGYPPF 378 Query: 913 --EYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 EY + + +W ++ + WML +P+ RP +++ Sbjct: 379 SEEYTDMTMDEQVLTGRLIFHAQWRRITV-----ETQNMIKWMLTVEPSNRPSAVELM 431
>Q8GYF5:WAKLR_ARATH Wall-associated receptor kinase-like 21 precursor - Arabidopsis| thaliana (Mouse-ear cress) Length = 620 Score = 63.5 bits (153), Expect = 2e-09 Identities = 62/258 (24%), Positives = 110/258 (42%), Gaps = 15/258 (5%) Frame = +1 Query: 190 RVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTY-----------AMKKVLIQ 336 R+L ++ E Y KE + ++D+ D++ GT A+K++ + Sbjct: 286 RLLCELAENSSVPFYTYKEIEKATDSFSDKNMLGTGAYGTVYAGEFPNSSCVAIKRLKHK 345 Query: 337 SREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDN 516 +D V EI++ S +HPNL+ LL E +L++ +GTL+ + Sbjct: 346 DTTSIDQVVNEIKLLSSVSHPNLVRLLGCCFA---------DGEPFLVYEFMPNGTLYQH 396 Query: 517 AAVMQSRKEFYSVLDVLRIFQQICEGLKHMHS-LDPPYAHNDVKPGNVLVTRQKGQAPLA 693 + + L L I Q + H+HS ++PP H D+K N+L+ + + Sbjct: 397 LQHERGQPPLSWQLR-LAIACQTANAIAHLHSSVNPPIYHRDIKSSNILLDHEFN----S 451 Query: 694 TLMDFGSSRPARNQIRSRSEALRLQEWAAEHCS-APFRAPELWDCPSHAD--IDERTDIW 864 + DFG SR + ++ A H S AP P D H D + +++D++ Sbjct: 452 KISDFGLSRLGMS-----------TDFEASHISTAPQGTPGYLDPQYHQDFQLSDKSDVY 500 Query: 865 SLGCTLYAIMYGVSPFEY 918 S G L I+ G ++ Sbjct: 501 SFGVVLVEIISGFKVIDF 518
>Q8WZ42:TITIN_HUMAN Titin - Homo sapiens (Human)| Length = 34350 Score = 63.5 bits (153), Expect = 2e-09 Identities = 68/303 (22%), Positives = 128/303 (42%), Gaps = 2/303 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++ + +G G F V+ E S TY K V ++ +Q+ LVK Sbjct: 32177 KYMIAEDLGRGEFGIVHRCVE---------------TSSKKTYMAKFVKVKGTDQV-LVK 32220 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD--NAAVMQSR 537 +EI + ++ H N+L L + + E ++F +F+ N + + Sbjct: 32221 KEISILNIARHRNILHLHESF---------ESMEELVMIFEFISGLDIFERINTSAFELN 32271 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + +++ Q+CE L+ +HS + H D++P N++ Q ++ +++FG + Sbjct: 32272 ER-----EIVSYVHQVCEALQFLHSHN--IGHFDIRPENIIY--QTRRSSTIKIIEFGQA 32322 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 R + + RL A E + APE+ H + TD+WSLG +Y ++ Sbjct: 32323 RQLKP-----GDNFRLLFTAPE-----YYAPEVHQ---HDVVSTATDMWSLGTLVYVLLS 32369 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDI 1077 G++PF L E+ + IMNA+ + + FV +L + R ++ Sbjct: 32370 GINPF---LAETNQQIIENIMNAEYTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEA 32426 Query: 1078 LLH 1086 L H Sbjct: 32427 LQH 32429
>Q9H2K8:TAOK3_HUMAN Serine/threonine-protein kinase TAO3 - Homo sapiens (Human)| Length = 898 Score = 63.5 bits (153), Expect = 2e-09 Identities = 80/307 (26%), Positives = 124/307 (40%), Gaps = 4/307 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E F L +IG G F VY A + H S V A+KK+ Q+ E+ Sbjct: 21 EELFIGLHEIGHGSFGAVYF----------ATNAHTSEV-----VAIKKMSYSGKQTHEK 65 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E++ HPN + ++ +K H A+L+ L G+ D ++ Sbjct: 66 WQDILKEVKFLRQLKHPNTI---EYKGCYLKE------HTAWLVMEYCL-GSASD---LL 112 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + K+ +++ I GL ++HS H D+K GN+L+T + GQ LA DF Sbjct: 113 EVHKKPLQEVEIAAITHGALHGLAYLHS--HALIHRDIKAGNILLT-EPGQVKLA---DF 166 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLY 885 GS+ A A P+ APE+ D + DIWSLG T Sbjct: 167 GSASMASP--------------ANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCI 212 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + P + ++ AQ P L S + D+ +FV + LQ P RP Sbjct: 213 ELAERKPPL-----FNMNAMSALYHIAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPT 267 Query: 1066 INDILLH 1086 ++L H Sbjct: 268 SAELLRH 274
>Q8BHI9:NIM1_MOUSE Serine/threonine-protein kinase NIM1 - Mus musculus (Mouse)| Length = 436 Score = 63.5 bits (153), Expect = 2e-09 Identities = 80/303 (26%), Positives = 125/303 (41%), Gaps = 6/303 (1%) Frame = +1 Query: 190 RVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLD----- 354 +V+R+I G Y ++ S + ++ + H A+K I + +LD Sbjct: 60 KVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIK---ILDKTKLDQKTQR 116 Query: 355 LVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 L+ EI +HPN++ L + ++ S + +L+ G LF + Sbjct: 117 LLSREISSMEKLHHPNIVRLYE--VVETLS-------KLHLVMEYAGGGELFGKISTEGK 167 Query: 535 RKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGS 714 E S L IF QI +KHMH + H D+K NV T + + DFG Sbjct: 168 LSEPESKL----IFSQILSAVKHMH--ENQIIHRDLKAENVFYTSRT----CVKVGDFGF 217 Query: 715 SRPARNQIRSRSEALRLQEWAAEHC-SAPFRAPELWDCPSHADIDERTDIWSLGCTLYAI 891 S + + E L C S P+ APEL+ + + DIW+LG LY + Sbjct: 218 ST-----VSKKGEMLNT------FCGSPPYAAPELFRDQHYVGV--YVDIWALGVLLYFM 264 Query: 892 MYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHIN 1071 + G PF E+ L+ +I+ PQ S P H+ + +LQP P R IN Sbjct: 265 VTGTMPFR---AETVAKLKKSILEGTYTIPQHVSEP----CHRLIRGVLQPTPTERYGIN 317 Query: 1072 DIL 1080 I+ Sbjct: 318 YIM 320
>Q6FV07:IPL1_CANGA Spindle assembly checkpoint kinase - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 358 Score = 63.5 bits (153), Expect = 2e-09 Identities = 75/282 (26%), Positives = 118/282 (41%), Gaps = 2/282 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F V R++G+G F VY V+ + A A++K I L +K Sbjct: 100 FEVGRKLGKGKFGKVYCVRHKKSGFICALK------------AIEKNEILQFNLLKQLKR 147 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 E+ + +HPN++ L H YLL ++G L+ + +++ F Sbjct: 148 EVDIQLGMDHPNIIKLYAHF---------HDEKRVYLLMEHSINGELYKS---LKNNGPF 195 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 VL I+Q I + L +MH H DVKP NVL+ G + L DFG S Sbjct: 196 NDVLASHYIYQ-IADALHYMHK--KRIIHRDVKPENVLI----GFDNVVKLADFGWS--I 246 Query: 727 RNQIRSRSEALRLQEWAAEHCSA-PFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 N S+ + L C + +PE+ + + DE+ D+W+LG Y ++ GV Sbjct: 247 LNPEGSKRKTL---------CGTIDYLSPEMI---TPREYDEQVDVWALGVLAYELVVGV 294 Query: 904 SPFEYALGESGGSLQL-AIMNAQLKWPQLPSPPYPDALHKFV 1026 PFE E+ L I+ L +P+ S D + K + Sbjct: 295 PPFE----ENSKELTYKRILKCDLNFPESISKDAKDLISKLL 332
>O59790:ARK1_SCHPO Serine/threonine-protein kinase ark1 - Schizosaccharomyces pombe| (Fission yeast) Length = 355 Score = 63.5 bits (153), Expect = 2e-09 Identities = 76/301 (25%), Positives = 120/301 (39%), Gaps = 1/301 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAA-RDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 F + + +G+G F VYL KE A + H S L+QS+ + V+ Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSE------------LVQSKIEKQ-VR 135 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 EI + S H N+L L H YL+ G L+ + ++ K Sbjct: 136 REIEIQSNLRHKNILRLYGHF---------HDEKRIYLILEFAGRGELYQH---LRRAKR 183 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 F + IFQ + L ++H H D+KP N+L+ G L DFG S Sbjct: 184 FSEEVASKYIFQ-MANALSYLHKKH--VIHRDIKPENILL----GIDGEIKLSDFGWSVH 236 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 A + R+ + + PE+ + H E+ D+WSLG Y + G Sbjct: 237 APSNRRTTLCG-----------TLDYLPPEMVEGKEHT---EKVDLWSLGVLTYEFLVGA 282 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILL 1083 PFE G S ++A ++ ++PS PDA ++ +LQ P R + ++ Sbjct: 283 PPFEDMSGHSATYKRIAKVDL-----KIPSFVPPDA-RDLISRLLQHNPEKRMSLEQVMR 336 Query: 1084 H 1086 H Sbjct: 337 H 337
>Q9NRP7:STK36_HUMAN Serine/threonine-protein kinase 36 - Homo sapiens (Human)| Length = 1315 Score = 63.2 bits (152), Expect = 2e-09 Identities = 76/307 (24%), Positives = 125/307 (40%), Gaps = 6/307 (1%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++ VL IGEG F VY + ++ A P L +S ++L ++ Sbjct: 3 KYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-------------LGRSEKELRNLQ 49 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF----DNAAVMQ 531 EI + HPN++ +LD S + D + ++ + +G LF D+ + + Sbjct: 50 REIEIMRGLRHPNIVHMLD-------SFETD---KEVVVVTDYAEGELFQILEDDGKLPE 99 Query: 532 SRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFG 711 + V I Q+ L ++HS H D+KP N+L+ + G L DFG Sbjct: 100 DQ--------VQAIAAQLVSALYYLHS--HRILHRDMKPQNILLAKGGG----IKLCDFG 145 Query: 712 SSRP--ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLY 885 +R + + + L + +PEL + D D+WS+GC LY Sbjct: 146 FARAMSTNTMVLTSIKGTPL-----------YMSPELVE---ERPYDHTADLWSVGCILY 191 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + G PF YA S L I+ ++WP SP + + F+ +L P R Sbjct: 192 ELAVGTPPF-YA--TSIFQLVSLILKDPVRWPSTISPCFKN----FLQGLLTKDPRQRLS 244 Query: 1066 INDILLH 1086 D+L H Sbjct: 245 WPDLLYH 251
>Q8VZD5:KSG5_ARATH Shaggy-related protein kinase epsilon - Arabidopsis thaliana| (Mouse-ear cress) Length = 410 Score = 63.2 bits (152), Expect = 2e-09 Identities = 79/322 (24%), Positives = 128/322 (39%), Gaps = 26/322 (8%) Frame = +1 Query: 199 RQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRV 378 R +G+G F V+ K + T A+KKVL R + E++ Sbjct: 78 RIVGQGSFGIVFQAKCLETGE---------------TVAIKKVLQDKRYK----NRELQT 118 Query: 379 SSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYL-LFPVHLDGTLFDNAAVMQSRKEFYSV 555 L +HPN++ L H + +T+ D E YL L ++ T++ + + + Sbjct: 119 MRLLDHPNVVSL-KHCFFS--TTEKD---ELYLNLVLEYVPETVYRVSKHYSRANQRMPI 172 Query: 556 LDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQ 735 + V QIC L ++H H D+KP N+LV Q L DFGS++ Sbjct: 173 IYVKLYTYQICRALAYIHG-GVGVCHRDIKPQNLLVNPHTHQVKLC---DFGSAKVL--- 225 Query: 736 IRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE 915 ++ + + CS +RAPEL + DIWS GC L ++ G F Sbjct: 226 -------VKGEPNISYICSRYYRAPEL--IFGATEYTTTIDIWSAGCVLAELLLGQPLFP 276 Query: 916 YALGESGGSLQLAIMN-----------------AQLKWPQLPSPPYPDALHK-------- 1020 GESG + I+ + K+PQ+ + P+ HK Sbjct: 277 ---GESGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHPWHKIFHKRTPPEAVD 333 Query: 1021 FVTWMLQPQPAMRPHINDILLH 1086 V+ +LQ P +R + ++H Sbjct: 334 LVSRLLQYSPNLRSTAMEAIVH 355
>P18654:KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 - Mus musculus (Mouse)| Length = 740 Score = 63.2 bits (152), Expect = 2e-09 Identities = 72/272 (26%), Positives = 123/272 (45%), Gaps = 1/272 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 +F +L+ +G+G F V+LVK+ S AR + V +KK ++ R+++ K Sbjct: 67 QFELLKVLGQGSFGKVFLVKK--ISGSDARQLYAMKV-------LKKATLKVRDRV-RTK 116 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E + NHP ++ L +A T+G + YL+ G LF S++ Sbjct: 117 MERDILVEVNHPFIVK-LHYAF----QTEG----KLYLILDFLRGGDLFTRL----SKEV 163 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 ++ DV ++ L H+HSL Y D+KP N+L+ ++G L DFG S+ Sbjct: 164 MFTEEDVKFYLAELALALDHLHSLGIIY--RDLKPENILLD-EEGHIKLT---DFGLSK- 216 Query: 724 ARNQIRSRSEALRLQEWAAEHC-SAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 E++ ++ A C + + APE+ + H + D WS G ++ ++ G Sbjct: 217 ---------ESIDHEKKAYSFCGTVEYMAPEVVNRRGHT---QSADWWSFGVLMFEMLTG 264 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSP 996 PF+ G+ I+ A+L PQ SP Sbjct: 265 TLPFQ---GKDRKETMTMILKAKLGMPQFLSP 293 Score = 57.8 bits (138), Expect = 1e-07 Identities = 57/242 (23%), Positives = 104/242 (42%), Gaps = 2/242 (0%) Frame = +1 Query: 193 VLRQIGEGGFAFV--YLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 +++Q+ F Y VKE + + H + + +A+K + R+ + ++ Sbjct: 407 IVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI 466 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 +R HPN II +K D + Y++ + G L D R++F Sbjct: 467 LLRYGQ---HPN--------IITLKDVYDDGKY-VYVVTELMKGGELLDKIL----RQKF 510 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 +S + + I + ++++H+ H D+KP N+L + G + DFG ++ Sbjct: 511 FSEREASAVLFTITKTVEYLHAQG--VVHRDLKPSNILYVDESGNPESIRICDFGFAK-- 566 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 Q+R+ + L + A F APE+ + D DIWSLG LY ++ G + Sbjct: 567 --QLRAENGLLMTPCYTAN-----FVAPEVLKRQGY---DAACDIWSLGVLLYTMLTGYT 616 Query: 907 PF 912 PF Sbjct: 617 PF 618
>P51812:KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 - Homo sapiens (Human)| Length = 740 Score = 63.2 bits (152), Expect = 2e-09 Identities = 72/272 (26%), Positives = 123/272 (45%), Gaps = 1/272 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 +F +L+ +G+G F V+LVK+ S AR + V +KK ++ R+++ K Sbjct: 67 QFELLKVLGQGSFGKVFLVKK--ISGSDARQLYAMKV-------LKKATLKVRDRV-RTK 116 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E + NHP ++ L +A T+G + YL+ G LF S++ Sbjct: 117 MERDILVEVNHPFIVK-LHYAF----QTEG----KLYLILDFLRGGDLFTRL----SKEV 163 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 ++ DV ++ L H+HSL Y D+KP N+L+ ++G L DFG S+ Sbjct: 164 MFTEEDVKFYLAELALALDHLHSLGIIY--RDLKPENILLD-EEGHIKLT---DFGLSK- 216 Query: 724 ARNQIRSRSEALRLQEWAAEHC-SAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 E++ ++ A C + + APE+ + H + D WS G ++ ++ G Sbjct: 217 ---------ESIDHEKKAYSFCGTVEYMAPEVVNRRGHT---QSADWWSFGVLMFEMLTG 264 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSP 996 PF+ G+ I+ A+L PQ SP Sbjct: 265 TLPFQ---GKDRKETMTMILKAKLGMPQFLSP 293 Score = 57.8 bits (138), Expect = 1e-07 Identities = 57/242 (23%), Positives = 104/242 (42%), Gaps = 2/242 (0%) Frame = +1 Query: 193 VLRQIGEGGFAFV--YLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 +++Q+ F Y VKE + + H + + +A+K + R+ + ++ Sbjct: 407 IVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI 466 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 +R HPN II +K D + Y++ + G L D R++F Sbjct: 467 LLRYGQ---HPN--------IITLKDVYDDGKY-VYVVTELMKGGELLDKIL----RQKF 510 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 +S + + I + ++++H+ H D+KP N+L + G + DFG ++ Sbjct: 511 FSEREASAVLFTITKTVEYLHAQG--VVHRDLKPSNILYVDESGNPESIRICDFGFAK-- 566 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 Q+R+ + L + A F APE+ + D DIWSLG LY ++ G + Sbjct: 567 --QLRAENGLLMTPCYTAN-----FVAPEVLKRQGY---DAACDIWSLGVLLYTMLTGYT 616 Query: 907 PF 912 PF Sbjct: 617 PF 618
>Q08942:NRKA_TRYBB Putative serine/threonine-protein kinase A - Trypanosoma brucei| brucei Length = 431 Score = 62.8 bits (151), Expect = 3e-09 Identities = 69/267 (25%), Positives = 113/267 (42%), Gaps = 8/267 (2%) Frame = +1 Query: 301 DGTYAMKKVLIQSR-EQLD--LVKEEIRVSSLFNHPNLLPLL-DHAIIAVKSTQGDWSHE 468 DG+ + KV+ S+ Q D + EI+ + NHPN++ + DH ++ Sbjct: 42 DGSLCVAKVMDLSKMSQRDKRYAQSEIKCLANCNHPNIIRYIEDHE-----------END 90 Query: 469 AYLLFPVHLDGTLFDNAAVMQSRKE--FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDV 642 L+ D D ++ + ++ + L +F Q+C L ++HS H D+ Sbjct: 91 RLLIVMEFADSGNLDEQIKLRGSGDARYFQEHEALFLFLQLCLALDYIHS--HKMLHRDI 148 Query: 643 KPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFR-APELW 819 K NVL+T L L DFG S + + A+ C P+ APELW Sbjct: 149 KSANVLLT----STGLVKLGDFGFSHQYEDTVSGVV--------ASTFCGTPYYLAPELW 196 Query: 820 DCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSP- 996 + + +++ D+WSLG LY IM PF S +L+ +M+ L P P Sbjct: 197 NNKRY---NKKADVWSLGVLLYEIMGMKKPF------SASNLK-GLMSKVLAGTYAPLPD 246 Query: 997 PYPDALHKFVTWMLQPQPAMRPHINDI 1077 + + V +L P RP + +I Sbjct: 247 SFSSEFKRVVDGILVADPNDRPSVREI 273
>O88831:KKCC2_RAT Calcium/calmodulin-dependent protein kinase kinase 2 - Rattus| norvegicus (Rat) Length = 587 Score = 62.8 bits (151), Expect = 3e-09 Identities = 61/255 (23%), Positives = 106/255 (41%), Gaps = 3/255 (1%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 IQ R ++ V +EI + +HPN++ L++ + D Y++F + G + Sbjct: 223 IQPRGPIEQVYQEIAILKKLDHPNVVKLVE----VLDDPNED---HLYMVFELVNQGPVM 275 Query: 511 DNAAVM---QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQ 681 + + + + FY FQ + +G++++H H D+KP N+LV G+ Sbjct: 276 EVPTLKPLSEDQARFY--------FQDLIKGIEYLHY--QKIIHRDIKPSNLLV----GE 321 Query: 682 APLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDI 861 + DFG S + S + + F APE + D+ Sbjct: 322 DGHIKIADFGVSNEFKGSDALLSNTVG---------TPAFMAPESLSETRKIFSGKALDV 372 Query: 862 WSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQ 1041 W++G TLY ++G PF + E L I + L++P P + L +T ML Sbjct: 373 WAMGVTLYCFVFGQCPF---MDERIMCLHSKIKSQALEFPD--QPDIAEDLKDLITRMLD 427 Query: 1042 PQPAMRPHINDILLH 1086 P R + +I LH Sbjct: 428 KNPESRIVVPEIKLH 442
>Q8C078:KKCC2_MOUSE Calcium/calmodulin-dependent protein kinase kinase 2 - Mus musculus| (Mouse) Length = 588 Score = 62.8 bits (151), Expect = 3e-09 Identities = 61/255 (23%), Positives = 106/255 (41%), Gaps = 3/255 (1%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 IQ R ++ V +EI + +HPN++ L++ + D Y++F + G + Sbjct: 224 IQPRGPIEQVYQEIAILKKLDHPNVVKLVE----VLDDPNED---HLYMVFELVNQGPVM 276 Query: 511 DNAAVM---QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQ 681 + + + + FY FQ + +G++++H H D+KP N+LV G+ Sbjct: 277 EVPTLKPLSEDQARFY--------FQDLIKGIEYLHY--QKIIHRDIKPSNLLV----GE 322 Query: 682 APLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDI 861 + DFG S + S + + F APE + D+ Sbjct: 323 DGHIKIADFGVSNEFKGSDALLSNTVG---------TPAFMAPESLSETRKIFSGKALDV 373 Query: 862 WSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQ 1041 W++G TLY ++G PF + E L I + L++P P + L +T ML Sbjct: 374 WAMGVTLYCFVFGQCPF---MDERIMCLHSKIKSQALEFPD--QPDIAEDLKDLITRMLD 428 Query: 1042 PQPAMRPHINDILLH 1086 P R + +I LH Sbjct: 429 KNPESRIVVPEIKLH 443
>Q96RR4:KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase kinase 2 - Homo sapiens| (Human) Length = 588 Score = 62.8 bits (151), Expect = 3e-09 Identities = 61/255 (23%), Positives = 106/255 (41%), Gaps = 3/255 (1%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 IQ R ++ V +EI + +HPN++ L++ + D Y++F + G + Sbjct: 224 IQPRGPIEQVYQEIAILKKLDHPNVVKLVE----VLDDPNED---HLYMVFELVNQGPVM 276 Query: 511 DNAAVM---QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQ 681 + + + + FY FQ + +G++++H H D+KP N+LV G+ Sbjct: 277 EVPTLKPLSEDQARFY--------FQDLIKGIEYLHY--QKIIHRDIKPSNLLV----GE 322 Query: 682 APLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDI 861 + DFG S + S + + F APE + D+ Sbjct: 323 DGHIKIADFGVSNEFKGSDALLSNTVG---------TPAFMAPESLSETRKIFSGKALDV 373 Query: 862 WSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQ 1041 W++G TLY ++G PF + E L I + L++P P + L +T ML Sbjct: 374 WAMGVTLYCFVFGQCPF---MDERIMCLHSKIKSQALEFPD--QPDIAEDLKDLITRMLD 428 Query: 1042 PQPAMRPHINDILLH 1086 P R + +I LH Sbjct: 429 KNPESRIVVPEIKLH 443
>P11275:KCC2A_RAT Calcium/calmodulin-dependent protein kinase type II alpha chain -| Rattus norvegicus (Rat) Length = 478 Score = 62.8 bits (151), Expect = 3e-09 Identities = 54/199 (27%), Positives = 88/199 (44%), Gaps = 1/199 (0%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 47 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGHH--YLIFDLVTG 94 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLV-TRQK 675 G LF++ +E+YS D QQI E + H H + H D+KP N+L+ ++ K Sbjct: 95 GELFEDIVA----REYYSEADASHCIQQILEAVLHCHQMG--VVHRDLKPENLLLASKLK 148 Query: 676 GQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERT 855 G A L DFG + + Q W + + +PE+ + + Sbjct: 149 GAA--VKLADFGLAIEVEGE---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPV 194 Query: 856 DIWSLGCTLYAIMYGVSPF 912 D+W+ G LY ++ G PF Sbjct: 195 DLWACGVILYILLVGYPPF 213
>Q5RCC4:KCC2A_PONPY Calcium/calmodulin-dependent protein kinase type II alpha chain -| Pongo pygmaeus (Orangutan) Length = 478 Score = 62.8 bits (151), Expect = 3e-09 Identities = 54/199 (27%), Positives = 88/199 (44%), Gaps = 1/199 (0%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 47 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGHH--YLIFDLVTG 94 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLV-TRQK 675 G LF++ +E+YS D QQI E + H H + H D+KP N+L+ ++ K Sbjct: 95 GELFEDIVA----REYYSEADASHCIQQILEAVLHCHQMG--VVHRDLKPENLLLASKLK 148 Query: 676 GQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERT 855 G A L DFG + + Q W + + +PE+ + + Sbjct: 149 GAA--VKLADFGLAIEVEGE---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPV 194 Query: 856 DIWSLGCTLYAIMYGVSPF 912 D+W+ G LY ++ G PF Sbjct: 195 DLWACGVILYILLVGYPPF 213
>P11798:KCC2A_MOUSE Calcium/calmodulin-dependent protein kinase type II alpha chain -| Mus musculus (Mouse) Length = 478 Score = 62.8 bits (151), Expect = 3e-09 Identities = 54/199 (27%), Positives = 88/199 (44%), Gaps = 1/199 (0%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 47 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGHH--YLIFDLVTG 94 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLV-TRQK 675 G LF++ +E+YS D QQI E + H H + H D+KP N+L+ ++ K Sbjct: 95 GELFEDIVA----REYYSEADASHCIQQILEAVLHCHQMG--VVHRDLKPENLLLASKLK 148 Query: 676 GQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERT 855 G A L DFG + + Q W + + +PE+ + + Sbjct: 149 GAA--VKLADFGLAIEVEGE---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPV 194 Query: 856 DIWSLGCTLYAIMYGVSPF 912 D+W+ G LY ++ G PF Sbjct: 195 DLWACGVILYILLVGYPPF 213
>Q9UQM7:KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II alpha chain -| Homo sapiens (Human) Length = 478 Score = 62.8 bits (151), Expect = 3e-09 Identities = 54/199 (27%), Positives = 88/199 (44%), Gaps = 1/199 (0%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 47 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGHH--YLIFDLVTG 94 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLV-TRQK 675 G LF++ +E+YS D QQI E + H H + H D+KP N+L+ ++ K Sbjct: 95 GELFEDIVA----REYYSEADASHCIQQILEAVLHCHQMG--VVHRDLKPENLLLASKLK 148 Query: 676 GQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERT 855 G A L DFG + + Q W + + +PE+ + + Sbjct: 149 GAA--VKLADFGLAIEVEGE---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPV 194 Query: 856 DIWSLGCTLYAIMYGVSPF 912 D+W+ G LY ++ G PF Sbjct: 195 DLWACGVILYILLVGYPPF 213
>P54736:PKN2_MYXXA Serine/threonine-protein kinase pkn2 - Myxococcus xanthus| Length = 830 Score = 62.4 bits (150), Expect = 4e-09 Identities = 65/259 (25%), Positives = 103/259 (39%), Gaps = 8/259 (3%) Frame = +1 Query: 163 DVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARD--RHPSHVSGDGTYAMKKVLIQ 336 D + + RFRVLR +G GG VYL ++ A H H Sbjct: 5 DSLVLDGRFRVLRPLGSGGMGEVYLGEQVSLGRKVAIKVLHHDLHAQAG----------- 53 Query: 337 SREQLDLVKEEIRVSSLFNHPNLLPLL------DHAIIAVKSTQGDWSHEAYLLFPVHLD 498 + K E R+ S HP ++ ++ DHA + ++ +G+ L+ V Sbjct: 54 ---MAERFKREARLLSAVEHPAVVRIVDFGESGDHACLVMEFVEGE------SLYDVLTP 104 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G + A L + QQ+ EGL +H D H D+KP NV +++ Sbjct: 105 GPMPPGRA--------------LPLLQQLAEGLAAIH--DKGIIHRDLKPENVFISK-SA 147 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + A L+DFG +R S + + E+ S PE A +D R+D Sbjct: 148 RGEQARLLDFGIARLVEPDAASSVSQIGVVLGTPEYLS-----PEQ---AVGAKVDTRSD 199 Query: 859 IWSLGCTLYAIMYGVSPFE 915 ++S G Y ++ G PF+ Sbjct: 200 LYSFGVLTYRVLSGRLPFD 218
>O08875:DCLK1_RAT Serine/threonine-protein kinase DCLK1 - Rattus norvegicus (Rat)| Length = 433 Score = 62.4 bits (150), Expect = 4e-09 Identities = 70/287 (24%), Positives = 119/287 (41%), Gaps = 2/287 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVL-IQSREQLDLV 360 R++V R IG+G FA +VKE S A YA+K + + R + ++ Sbjct: 82 RYKVGRTIGDGNFA---VVKECIERSTARE------------YALKIIKKSKCRGKEHMI 126 Query: 361 KEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRK 540 + E+ + HPN++ L++ D E YL+ + G LFD A+ + K Sbjct: 127 QNEVSILRRVKHPNIVLLIEEM---------DVPTELYLVMELVKGGDLFD--AITSTSK 175 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 Y+ D + + +K++HSL+ H D+KP N+LV + + L DFG + Sbjct: 176 --YTERDASGMLYNLASAIKYLHSLN--IVHRDIKPENLLVYEHQDGSKSLKLGDFGLAT 231 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 + + C P + APE+ + + DIW+ G Y ++ Sbjct: 232 IVDGPLYT-------------VCGTPTYVAPEI---IAETGYGLKVDIWAAGVITYILLC 275 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWML 1038 G PF G+ L I+ Q+ +P D+ + + ML Sbjct: 276 GFPPFR-GSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMML 321
>Q9JLM8:DCLK1_MOUSE Serine/threonine-protein kinase DCLK1 - Mus musculus (Mouse)| Length = 756 Score = 62.4 bits (150), Expect = 4e-09 Identities = 70/287 (24%), Positives = 119/287 (41%), Gaps = 2/287 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVL-IQSREQLDLV 360 R++V R IG+G FA +VKE S A YA+K + + R + ++ Sbjct: 405 RYKVGRTIGDGNFA---VVKECIERSTARE------------YALKIIKKSKCRGKEHMI 449 Query: 361 KEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRK 540 + E+ + HPN++ L++ D E YL+ + G LFD A+ + K Sbjct: 450 QNEVSILRRVKHPNIVLLIEEM---------DVPTELYLVMELVKGGDLFD--AITSTSK 498 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 Y+ D + + +K++HSL+ H D+KP N+LV + + L DFG + Sbjct: 499 --YTERDASGMLYNLASAIKYLHSLN--IVHRDIKPENLLVYEHQDGSKSLKLGDFGLAT 554 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 + + C P + APE+ + + DIW+ G Y ++ Sbjct: 555 IVDGPLYT-------------VCGTPTYVAPEI---IAETGYGLKVDIWAAGVITYILLC 598 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWML 1038 G PF G+ L I+ Q+ +P D+ + + ML Sbjct: 599 GFPPFR-GSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMML 644
>P54645:AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Rattus| norvegicus (Rat) Length = 548 Score = 62.4 bits (150), Expect = 4e-09 Identities = 73/253 (28%), Positives = 107/253 (42%), Gaps = 1/253 (0%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 I+S + + ++ EI+ LF HP+++ L V ST D +++ G LF Sbjct: 52 IRSLDVVGKIRREIQNLKLFRHPHIIKLYQ-----VISTPSD----IFMVMEYVSGGELF 102 Query: 511 DNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 D E S R+FQQI G+ + H H D+KP NVL+ Sbjct: 103 DYICKNGRLDEKES----RRLFQQILSGVDYCHR--HMVVHRDLKPENVLLDAHMN---- 152 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWS 867 A + DFG S + S E LR C +P + APE+ +A + DIWS Sbjct: 153 AKIADFGLSN-----MMSDGEFLRTS------CGSPNYAAPEVISGRLYAGPE--VDIWS 199 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 G LYA++ G PF+ + +L I + PQ +P ++ + MLQ Sbjct: 200 SGVILYALLCGTLPFD---DDHVPTLFKKICDGIFYTPQYLNP----SVISLLKHMLQVD 252 Query: 1048 PAMRPHINDILLH 1086 P R I DI H Sbjct: 253 PMKRATIKDIREH 265
>Q5RDH5:AAPK1_PONPY 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Pongo| pygmaeus (Orangutan) Length = 550 Score = 62.4 bits (150), Expect = 4e-09 Identities = 73/253 (28%), Positives = 107/253 (42%), Gaps = 1/253 (0%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 I+S + + ++ EI+ LF HP+++ L V ST D +++ G LF Sbjct: 54 IRSLDVVGKIRREIQNLKLFRHPHIIKLYQ-----VISTPSD----IFMVMEYVSGGELF 104 Query: 511 DNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 D E S R+FQQI G+ + H H D+KP NVL+ Sbjct: 105 DYICKNGRLDEKES----RRLFQQILSGVDYCHR--HMVVHRDLKPENVLLDAHMN---- 154 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWS 867 A + DFG S + S E LR C +P + APE+ +A + DIWS Sbjct: 155 AKIADFGLSN-----MMSDGEFLRTS------CGSPNYAAPEVISGRLYAGPE--VDIWS 201 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 G LYA++ G PF+ + +L I + PQ +P ++ + MLQ Sbjct: 202 SGVILYALLCGTLPFD---DDHVPTLFKKICDGIFYTPQYLNP----SVISLLKHMLQVD 254 Query: 1048 PAMRPHINDILLH 1086 P R I DI H Sbjct: 255 PMKRATIKDIREH 267
>Q5EG47:AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Mus| musculus (Mouse) Length = 548 Score = 62.4 bits (150), Expect = 4e-09 Identities = 73/253 (28%), Positives = 107/253 (42%), Gaps = 1/253 (0%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 I+S + + ++ EI+ LF HP+++ L V ST D +++ G LF Sbjct: 52 IRSLDVVGKIRREIQNLKLFRHPHIIKLYQ-----VISTPSD----IFMVMEYVSGGELF 102 Query: 511 DNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 D E S R+FQQI G+ + H H D+KP NVL+ Sbjct: 103 DYICKNGRLDEKES----RRLFQQILSGVDYCHR--HMVVHRDLKPENVLLDAHMN---- 152 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWS 867 A + DFG S + S E LR C +P + APE+ +A + DIWS Sbjct: 153 AKIADFGLSN-----MMSDGEFLRTS------CGSPNYAAPEVISGRLYAGPE--VDIWS 199 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 G LYA++ G PF+ + +L I + PQ +P ++ + MLQ Sbjct: 200 SGVILYALLCGTLPFD---DDHVPTLFKKICDGIFYTPQYLNP----SVISLLKHMLQVD 252 Query: 1048 PAMRPHINDILLH 1086 P R I DI H Sbjct: 253 PMKRAAIKDIREH 265
>Q13131:AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Homo| sapiens (Human) Length = 550 Score = 62.4 bits (150), Expect = 4e-09 Identities = 73/253 (28%), Positives = 107/253 (42%), Gaps = 1/253 (0%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 I+S + + ++ EI+ LF HP+++ L V ST D +++ G LF Sbjct: 54 IRSLDVVGKIRREIQNLKLFRHPHIIKLYQ-----VISTPSD----IFMVMEYVSGGELF 104 Query: 511 DNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 D E S R+FQQI G+ + H H D+KP NVL+ Sbjct: 105 DYICKNGRLDEKES----RRLFQQILSGVDYCHR--HMVVHRDLKPENVLLDAHMN---- 154 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWS 867 A + DFG S + S E LR C +P + APE+ +A + DIWS Sbjct: 155 AKIADFGLSN-----MMSDGEFLRTS------CGSPNYAAPEVISGRLYAGPE--VDIWS 201 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 G LYA++ G PF+ + +L I + PQ +P ++ + MLQ Sbjct: 202 SGVILYALLCGTLPFD---DDHVPTLFKKICDGIFYTPQYLNP----SVISLLKHMLQVD 254 Query: 1048 PAMRPHINDILLH 1086 P R I DI H Sbjct: 255 PMKRATIKDIREH 267
>Q53UA7:TAOK3_RAT Serine/threonine-protein kinase TAO3 - Rattus norvegicus (Rat)| Length = 898 Score = 62.0 bits (149), Expect = 6e-09 Identities = 81/309 (26%), Positives = 124/309 (40%), Gaps = 6/309 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E F L +IG G F VY A + H + V A+KK+ Q+ E+ Sbjct: 21 EELFIDLHEIGHGSFGAVYF----------ATNAHTNEV-----VAIKKMSYSGKQTHEK 65 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E+R HPN + ++ +K H A+L+ L G+ D ++ Sbjct: 66 WQDILKEVRFLQQLKHPNTI---EYKGCYLKE------HTAWLVMEYCL-GSASD---LL 112 Query: 529 QSRKEFYSVLDVLRIFQQICEGLK--HMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLM 702 + K+ +++ I +GL H HSL H D+K GN+L+T + GQ LA Sbjct: 113 EVHKKPLQEVEIAAITHGALQGLAYLHFHSL----IHRDIKAGNILLT-EPGQVKLA--- 164 Query: 703 DFGSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCT 879 DFGS+ A A P+ APE+ D + DIWSLG T Sbjct: 165 DFGSASMASP--------------ANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGIT 210 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 + P + ++ AQ P L S + D+ +FV + L P R Sbjct: 211 CIELAERKPPL-----FNMNAMSALYHIAQNDSPTLQSREWTDSFRRFVDYCLHKIPQER 265 Query: 1060 PHINDILLH 1086 P ++L H Sbjct: 266 PAAAELLRH 274
>Q16566:KCC4_HUMAN Calcium/calmodulin-dependent protein kinase type IV - Homo sapiens| (Human) Length = 473 Score = 62.0 bits (149), Expect = 6e-09 Identities = 69/281 (24%), Positives = 112/281 (39%), Gaps = 14/281 (4%) Frame = +1 Query: 112 CSISGLNALYDAATGGG-----DVWINERR-------FRVLRQIGEGGFAFVYLVKEHDA 255 CS S +++ +A G D WI+ F V ++G G + VY K+ Sbjct: 9 CSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGT 68 Query: 256 SSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIA 435 YA+K +++ +V+ EI V +HPN++ L + Sbjct: 69 QKP---------------YALK--VLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIF--- 108 Query: 436 VKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSL 615 + E L+ + G LFD K +YS D +QI E + ++H Sbjct: 109 ------ETPTEISLVLELVTGGELFDRIV----EKGYYSERDAADAVKQILEAVAYLH-- 156 Query: 616 DPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSA 795 + H D+KP N+L APL + DFG S+ +Q+ ++ C Sbjct: 157 ENGIVHRDLKPENLLYATPAPDAPLK-IADFGLSKIVEHQVLMKTV-----------CGT 204 Query: 796 P-FRAPE-LWDCPSHADIDERTDIWSLGCTLYAIMYGVSPF 912 P + APE L C ++D +WS+G Y ++ G PF Sbjct: 205 PGYCAPEILRGCAYGPEVD----MWSVGIITYILLCGFEPF 241
>Q00168:KCC2A_DROME Calcium/calmodulin-dependent protein kinase type II alpha chain -| Drosophila melanogaster (Fruit fly) Length = 530 Score = 62.0 bits (149), Expect = 6e-09 Identities = 51/185 (27%), Positives = 79/185 (42%) Frame = +1 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 ++ E R+ +HPN++ L D S Q + H YL+F + G LF++ Sbjct: 58 LEREARICRKLHHPNIVRLHD-------SIQEENYH--YLVFDLVTGGELFEDIVA---- 104 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 +EFYS D QQI E + H H H D+KP N+L+ K + L DFG + Sbjct: 105 REFYSEADASHCIQQILESVNHCH--QNGVVHRDLKPENLLLA-SKAKGAAVKLADFGLA 161 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 + Q W + + +PE+ + + DIW+ G LY ++ Sbjct: 162 IEVQGD---------HQAWFGFAGTPGYLSPEVLKKEPYG---KSVDIWACGVILYILLV 209 Query: 898 GVSPF 912 G PF Sbjct: 210 GYPPF 214
>P39009:DUN1_YEAST DNA damage response protein kinase DUN1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 513 Score = 62.0 bits (149), Expect = 6e-09 Identities = 61/249 (24%), Positives = 107/249 (42%), Gaps = 7/249 (2%) Frame = +1 Query: 361 KEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRK 540 +EE + HPN++ LLD + + +Q + YL+ DG LF+ RK Sbjct: 246 REETNILMRVQHPNIVNLLDSFVEPISKSQ----IQKYLVLEKIDDGELFERIV----RK 297 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 + +F+Q+ GLK++H + H D+KP N+L+ + + P + + G Sbjct: 298 TCLRQDESKALFKQLLTGLKYLHEQN--IIHRDIKPENILLNITRRENP--SQVQLGPWD 353 Query: 721 PARNQIRSRSEALRLQEWAAEH------CSAP-FRAPELWDCPSHADIDERTDIWSLGCT 879 I+ + L ++ E C P + APE+ + + D+WS G Sbjct: 354 EDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTS---KVDLWSAGVI 410 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 LY + G PF LG SL+ I+ A+ + D++ ++ +L P R Sbjct: 411 LYVCLCGFPPFSDQLGPP--SLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDER 468 Query: 1060 PHINDILLH 1086 +I++ L H Sbjct: 469 YNIDEALNH 477
>O88764:DAPK3_RAT Death-associated protein kinase 3 - Rattus norvegicus (Rat)| Length = 448 Score = 62.0 bits (149), Expect = 6e-09 Identities = 61/254 (24%), Positives = 113/254 (44%), Gaps = 2/254 (0%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQL-- 351 E + + ++G G FA V ++ + A + K+ L SR + Sbjct: 10 EDHYEMGEELGSGQFAIVRKCQQKGTGMEYA-----------AKFIKKRRLPSSRRGVSR 58 Query: 352 DLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQ 531 + ++ E+ + HPN++ L H + K+ + L+ + G LFD A + Sbjct: 59 EEIEREVSILREIRHPNIITL--HDVFENKT-------DVVLILELVSGGELFDFLAEKE 109 Query: 532 SRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFG 711 S E + + +QI +G+ ++HS AH D+KP N+++ + +P L+DFG Sbjct: 110 SLTED----EATQFLKQILDGVHYLHS--KRIAHFDLKPENIMLLDKHAASPRIKLIDFG 163 Query: 712 SSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAI 891 + ++I + SE + + F APE+ ++ + D+WS+G Y + Sbjct: 164 IA----HRIEAGSEFKNI------FGTPEFVAPEI---VNYEPLGLEADMWSIGVITYIL 210 Query: 892 MYGVSPFEYALGES 933 + G SPF LGE+ Sbjct: 211 LSGASPF---LGET 221
>O54784:DAPK3_MOUSE Death-associated protein kinase 3 - Mus musculus (Mouse)| Length = 448 Score = 62.0 bits (149), Expect = 6e-09 Identities = 61/254 (24%), Positives = 113/254 (44%), Gaps = 2/254 (0%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQL-- 351 E + + ++G G FA V ++ + A + K+ L SR + Sbjct: 10 EDHYEMGEELGSGQFAIVRKCQQKGTGMEYA-----------AKFIKKRRLPSSRRGVSR 58 Query: 352 DLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQ 531 + ++ E+ + HPN++ L H + K+ + L+ + G LFD A + Sbjct: 59 EEIEREVSILREIRHPNIITL--HDVFENKT-------DVVLILELVSGGELFDFLAEKE 109 Query: 532 SRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFG 711 S E + + +QI +G+ ++HS AH D+KP N+++ + +P L+DFG Sbjct: 110 SLTED----EATQFLKQILDGVHYLHS--KRIAHFDLKPENIMLLDKHAASPRIKLIDFG 163 Query: 712 SSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAI 891 + ++I + SE + + F APE+ ++ + D+WS+G Y + Sbjct: 164 IA----HRIEAGSEFKNI------FGTPEFVAPEI---VNYEPLGLEADMWSIGVITYIL 210 Query: 892 MYGVSPFEYALGES 933 + G SPF LGE+ Sbjct: 211 LSGASPF---LGET 221
>Q09137:AAPK2_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Rattus| norvegicus (Rat) Length = 552 Score = 62.0 bits (149), Expect = 6e-09 Identities = 72/253 (28%), Positives = 108/253 (42%), Gaps = 1/253 (0%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 I+S + + +K EI+ LF HP+++ L V ST D+ +++ G LF Sbjct: 52 IRSLDVVGKIKREIQNLKLFRHPHIIKLYQ-----VISTPTDF----FMVMEYVSGGELF 102 Query: 511 DNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 D +E ++ R+FQQI + + H H D+KP NVL+ Q Sbjct: 103 DYICKHGRVEE----VEARRLFQQILSAVDYCHR--HMVVHRDLKPENVLLDAQMN---- 152 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWS 867 A + DFG S + S E LR C +P + APE+ +A + DIWS Sbjct: 153 AKIADFGLSN-----MMSDGEFLRTS------CGSPNYAAPEVISGRLYAGPE--VDIWS 199 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 G LYA++ G PF+ E +L I P+ + ++ + MLQ Sbjct: 200 CGVILYALLCGTLPFD---DEHVPTLFKKIRGGVFYIPEYLN----RSIATLLMHMLQVD 252 Query: 1048 PAMRPHINDILLH 1086 P R I DI H Sbjct: 253 PLKRATIKDIREH 265
>Q28948:AAPK2_PIG 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Sus| scrofa (Pig) Length = 552 Score = 62.0 bits (149), Expect = 6e-09 Identities = 72/253 (28%), Positives = 108/253 (42%), Gaps = 1/253 (0%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 I+S + + +K EI+ LF HP+++ L V ST D+ +++ G LF Sbjct: 52 IRSLDVVGKIKREIQNLKLFRHPHIIKLYQ-----VISTPTDF----FMVMEYVSGGELF 102 Query: 511 DNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 D +E ++ R+FQQI + + H H D+KP NVL+ Q Sbjct: 103 DYICKHGRVEE----MEARRLFQQILSAVDYCHR--HMVVHRDLKPENVLLDAQMN---- 152 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWS 867 A + DFG S + S E LR C +P + APE+ +A + DIWS Sbjct: 153 AKIADFGLSN-----MMSDGEFLRTS------CGSPNYAAPEVISGRLYAGPE--VDIWS 199 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 G LYA++ G PF+ E +L I P+ + ++ + MLQ Sbjct: 200 CGVILYALLCGTLPFD---DEHVPTLFKKIRGGVFYIPEYLN----RSVATLLMHMLQVD 252 Query: 1048 PAMRPHINDILLH 1086 P R I DI H Sbjct: 253 PLKRATIKDIREH 265
>Q12152:YP150_YEAST Putative serine/threonine-protein kinase YPL150W - Saccharomyces| cerevisiae (Baker's yeast) Length = 901 Score = 61.6 bits (148), Expect = 7e-09 Identities = 73/323 (22%), Positives = 132/323 (40%), Gaps = 1/323 (0%) Frame = +1 Query: 121 SGLNALYDAATGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSG 300 S N LY T D +++L+QIGEG F VYL P+H Sbjct: 21 SSYNRLYSQFTS--DELTEVGNYKILKQIGEGSFGKVYLALHR-----------PTH--- 64 Query: 301 DGTYAMKKVLIQSREQLDL-VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYL 477 +KV +++ ++ D + E+ F+ P + L + +I +S + ++ Sbjct: 65 ------RKVCLKTSDKNDPNIVREVFYHRQFDFPYITKLYE--VIVTES-------KVWM 109 Query: 478 LFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNV 657 L+D+ ++ S+L+ +F QI + + HS+ H D+K N+ Sbjct: 110 ALEYCPGKELYDHLLSLRR----ISLLECGELFAQISGAVYYAHSMH--CVHRDLKLENI 163 Query: 658 LVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHA 837 L+ + A L DFG +R + + + + APEL + ++ Sbjct: 164 LLDKNGN----AKLTDFGFTRECMTKTTLETVC----------GTTVYMAPELIERRTYD 209 Query: 838 DIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALH 1017 + DIWSLG LY ++ G PF+ + + I+N + P+ + PD Sbjct: 210 GF--KIDIWSLGVILYTLITGYLPFD---DDDEAKTKWKIVNEE---PKYDAKVIPDDAR 261 Query: 1018 KFVTWMLQPQPAMRPHINDILLH 1086 ++ +L P RP ++ +L H Sbjct: 262 DLISRLLAKNPGERPSLSQVLRH 284
>Q39008:M3K1_ARATH Mitogen-activated protein kinase kinase kinase 1 - Arabidopsis| thaliana (Mouse-ear cress) Length = 608 Score = 61.6 bits (148), Expect = 7e-09 Identities = 74/277 (26%), Positives = 117/277 (42%), Gaps = 12/277 (4%) Frame = +1 Query: 292 VSGDGTY-AMKKVLI-----QSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQG 453 +SGDG + A+K+V + Q++E + ++ EI++ S H N I+ + T Sbjct: 351 ISGDGDFFAVKEVSLLDQGSQAQECIQQLEGEIKLLSQLQHQN--------IVRYRGTAK 402 Query: 454 DWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAH 633 D S+ Y+ + G+L Q R S+ +QI +GLK++H D + H Sbjct: 403 DGSN-LYIFLELVTQGSLLKLYQRYQLRDSVVSLYT-----RQILDGLKYLH--DKGFIH 454 Query: 634 NDVKPGNVLVTRQKGQAPLATLMDFGSSRPAR-NQIRSRSEALRLQEWAAEHCSAPF-RA 807 D+K N+LV G LA DFG ++ ++ N I+S PF A Sbjct: 455 RDIKCANILVDAN-GAVKLA---DFGLAKVSKFNDIKSCK-------------GTPFWMA 497 Query: 808 PELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQL 987 PE+ + DIWSLGCT+ + G P+ L + A + + Sbjct: 498 PEVINRKDSDGYGSPADIWSLGCTVLEMCTGQIPYS----------DLEPVQALFRIGRG 547 Query: 988 PSPPYPDAL----HKFVTWMLQPQPAMRPHINDILLH 1086 P PD L F+ L+ P RP ++L H Sbjct: 548 TLPEVPDTLSLDARLFILKCLKVNPEERPTAAELLNH 584
>Q18846:KS6A2_CAEEL Putative ribosomal protein S6 kinase alpha-2 - Caenorhabditis elegans| Length = 772 Score = 61.6 bits (148), Expect = 7e-09 Identities = 62/259 (23%), Positives = 112/259 (43%), Gaps = 4/259 (1%) Frame = +1 Query: 325 VLIQSREQLDLVKEEIRVSSLFN-HPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDG 501 V I S++ + E R+ + HPN++ L D D H YL+ + Sbjct: 410 VKIVSQKFASQAQREARILEMVQGHPNIVQLHD--------VHSDPLH-FYLVMEI---- 456 Query: 502 TLFDNAAVMQSRK-EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 L N + + RK E ++ + I +Q+ +K++H D H D+KP N+L Sbjct: 457 -LTGNELLERIRKLERFTESEAADIMRQLVSAVKYLH--DKRIVHRDLKPENILFESIDS 513 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDC-PSHADIDERT 855 A L L+DFG +R N + + +++++ + + APE+ D S + +E+ Sbjct: 514 SARLR-LVDFGFARLLPNSMEQQLKSVQVLRKMTPCFTLQYAAPEVLDVGDSQPEYNEQC 572 Query: 856 DIWSLGCTLYAIMYGVSPFE-YALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTW 1032 D+WSLG L+ ++ G PF + ES + I A+ + +T Sbjct: 573 DLWSLGVVLFTMLSGQVPFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADAKNLITG 632 Query: 1033 MLQPQPAMRPHINDILLHV 1089 +L P R + ++ H+ Sbjct: 633 LLTVDPKKRLSMQELTAHM 651
>Q501V0:KPSH1_DANRE Serine/threonine-protein kinase H1 homolog - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 422 Score = 61.6 bits (148), Expect = 7e-09 Identities = 65/302 (21%), Positives = 121/302 (40%), Gaps = 1/302 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++ + IG G F+ V V+ H S YA+K + + RE ++ + Sbjct: 95 KYDIKALIGRGSFSRVVRVE---------------HRSTRQPYAIKMIETRYREGREVCE 139 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E+ V H N++ L++ + + Y++ + G LFD S Sbjct: 140 SELCVLRRVRHTNIIQLMEVF---------ETAERVYMVMELATGGELFDRIITRGS--- 187 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 ++ D R+ Q + +G+K++H+L H D+KP N+L + + + DFG + Sbjct: 188 -FTERDATRVLQMVLDGVKYLHTLG--ITHRDLKPENLLYYHPGADSKIM-ITDFGLA-- 241 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 R + + ++ C P + APE+ + + D+W+LG Y ++ G Sbjct: 242 ---STRKKGDECLMKTT----CGTPEYIAPEILVRKPYTNA---VDMWALGVISYILLSG 291 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PFE ++ L I+ + + P P + F+ +L P R L Sbjct: 292 TMPFE---DDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDFIDRVLTVDPNERLSAGQAL 348 Query: 1081 LH 1086 H Sbjct: 349 KH 350
>Q8BRK8:AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Mus| musculus (Mouse) Length = 552 Score = 61.6 bits (148), Expect = 7e-09 Identities = 70/254 (27%), Positives = 109/254 (42%), Gaps = 2/254 (0%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 I+S + + +K EI+ LF HP+++ L V ST D+ +++ G LF Sbjct: 52 IRSLDVVGKIKREIQNLKLFRHPHIIKLYQ-----VISTPTDF----FMVMEYVSGGELF 102 Query: 511 DNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 D +E ++ R+FQQI + + H H D+KP NVL+ Q Sbjct: 103 DYICKHGRVEE----VEARRLFQQILSAVDYCHR--HMVVHRDLKPENVLLDAQMN---- 152 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWS 867 A + DFG S + S E LR C +P + APE+ +A + DIWS Sbjct: 153 AKIADFGLSN-----MMSDGEFLRTS------CGSPNYAAPEVISGRLYAGPE--VDIWS 199 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPD-ALHKFVTWMLQP 1044 G LYA++ G PF+ + + +++ P Y + ++ + MLQ Sbjct: 200 CGVILYALLCGTLPFD--------DEHVPTLFKKIRGGVFYIPDYLNRSVATLLMHMLQV 251 Query: 1045 QPAMRPHINDILLH 1086 P R I DI H Sbjct: 252 DPLKRATIKDIREH 265
>Q7T6X2:YR826_MIMIV Putative serine/threonine-protein kinase/receptor R826 precursor -| Mimivirus Length = 1657 Score = 61.2 bits (147), Expect = 9e-09 Identities = 70/314 (22%), Positives = 129/314 (41%), Gaps = 6/314 (1%) Frame = +1 Query: 172 INERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQL 351 IN ++ QIG G + VY K + A+KK + Q ++ Sbjct: 1394 INYDEIKMGEQIGLGSYGVVYRGKWKNVD-----------------VAIKKFIKQKIDEN 1436 Query: 352 DL--VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAV 525 L ++EEI +HPN++ ++ ++ ++ G L D Sbjct: 1437 HLLGIREEIAFLKKLHHPNIITMVGASLK---------KPNICIVTEYMAKGNLRDAMRT 1487 Query: 526 MQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMD 705 + E++ + +L I +G+ ++HS DPP H D+KP N+L+ + D Sbjct: 1488 CTPKLEWHQKIKIL---VNIAKGISYLHSFDPPIIHRDIKPSNILIDENWN----VKIAD 1540 Query: 706 FGSSR-PARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADI-DERTDIWSLGC 876 FG +R N I +R C P + APE+ DI DE+ D++S G Sbjct: 1541 FGFARIKEENAIMTR-------------CGTPCWTAPEI----IRNDIYDEKVDVFSFGI 1583 Query: 877 TLYAIMYGVSPFEYALGESGGSLQLAIM-NAQLKWPQLPSPPYPDALHKFVTWMLQPQPA 1053 ++ ++ PF +G + + + I+ + + K PQ P+ K + + Sbjct: 1584 VMWEVLTCKEPF---IGANFMKITMDILEDVRPKIPQ----DCPEEFAKLMRKCWHAKST 1636 Query: 1054 MRPHINDILLHVDK 1095 RP ++D+++ + K Sbjct: 1637 KRPTMDDVIIVLAK 1650
>O55047:TLK2_MOUSE Serine/threonine-protein kinase tousled-like 2 - Mus musculus (Mouse)| Length = 718 Score = 61.2 bits (147), Expect = 9e-09 Identities = 64/283 (22%), Positives = 109/283 (38%), Gaps = 9/283 (3%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R+ +L +G GGF+ VY + D R Y K+ ++ D K Sbjct: 407 RYLLLHLLGRGGFSEVY------KAFDLTEQR----------YVAVKIHQLNKNWRDEKK 450 Query: 364 E--------EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNA 519 E E R+ +HP ++ L D+ + S F L+ ++ Sbjct: 451 ENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDS------------FCTVLEYCEGNDL 498 Query: 520 AVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATL 699 + + S + I QI LK+++ + PP H D+KPGN+L+ + + Sbjct: 499 DFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEI-KI 557 Query: 700 MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSH-ADIDERTDIWSLGC 876 DFG S+ + + + + L A + + PE + I + D+WS+G Sbjct: 558 TDFGLSKIMDDDSYNSVDGMELTSQGAG--TYWYLPPECFVVGKEPPKISNKVDVWSVGV 615 Query: 877 TLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYP 1005 Y +YG PF G + + N LK ++ PP P Sbjct: 616 IFYQCLYGRKPF----GHNQSQQDILQENTILKATEVQFPPKP 654
>Q86UE8:TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 - Homo sapiens (Human)| Length = 772 Score = 61.2 bits (147), Expect = 9e-09 Identities = 64/283 (22%), Positives = 109/283 (38%), Gaps = 9/283 (3%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R+ +L +G GGF+ VY + D R Y K+ ++ D K Sbjct: 461 RYLLLHLLGRGGFSEVY------KAFDLTEQR----------YVAVKIHQLNKNWRDEKK 504 Query: 364 E--------EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNA 519 E E R+ +HP ++ L D+ + S F L+ ++ Sbjct: 505 ENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDS------------FCTVLEYCEGNDL 552 Query: 520 AVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATL 699 + + S + I QI LK+++ + PP H D+KPGN+L+ + + Sbjct: 553 DFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEI-KI 611 Query: 700 MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSH-ADIDERTDIWSLGC 876 DFG S+ + + + + L A + + PE + I + D+WS+G Sbjct: 612 TDFGLSKIMDDDSYNSVDGMELTSQGAG--TYWYLPPECFVVGKEPPKISNKVDVWSVGV 669 Query: 877 TLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYP 1005 Y +YG PF G + + N LK ++ PP P Sbjct: 670 IFYQCLYGRKPF----GHNQSQQDILQENTILKATEVQFPPKP 708
>Q6DD27:TAOK3_XENLA Serine/threonine-protein kinase TAO3 - Xenopus laevis (African clawed| frog) Length = 896 Score = 61.2 bits (147), Expect = 9e-09 Identities = 78/304 (25%), Positives = 128/304 (42%), Gaps = 1/304 (0%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDL 357 ER F L +IG G F VY + A + +Y+ K++ + + D+ Sbjct: 21 ERIFVDLHEIGHGSFGAVYFATNSTTNEIVAVKKM--------SYSGKQM---NEKWQDI 69 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 +KE ++ HPN + ++ +K H A+L+ L G+ D +++ Sbjct: 70 IKE-VKFLQQLKHPNTI---EYKGCYLKD------HTAWLVMEYCL-GSASD---LLEVH 115 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 K+ +++ I +GL ++HS + H D+K GN+L+T + GQ LA DFGS+ Sbjct: 116 KKPLQEVEIAAITHGALQGLAYLHSHN--MIHRDIKAGNILLT-EPGQVKLA---DFGSA 169 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 S+S A P+ APE+ D + DIWSLG T + Sbjct: 170 --------SKSSP------ANSFVGTPYWMAPEVILAMDEGQYDGKIDIWSLGITCIELA 215 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHIND 1074 P + ++ AQ + P L S + D+ FV + LQ P RP + Sbjct: 216 ERKPPL-----FNMNAMSALYHIAQNESPTLQSNEWTDSFKGFVDYCLQKLPQERPASLE 270 Query: 1075 ILLH 1086 +L H Sbjct: 271 LLRH 274
>Q8BZN4:NUAK2_MOUSE NUAK family SNF1-like kinase 2 - Mus musculus (Mouse)| Length = 639 Score = 61.2 bits (147), Expect = 9e-09 Identities = 68/303 (22%), Positives = 120/303 (39%), Gaps = 2/303 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R+ L +G+G + V +E A + +++K I+ + L ++ Sbjct: 56 RYEFLETLGKGTYGKVKKARESSGRLVAIK-------------SIRKDKIKDEQDLLHIR 102 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKS-TQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRK 540 EI + S NHP+++ + H + + T + S + ++ G L+D S + Sbjct: 103 REIEIMSSLNHPHIIAI--HEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYI----SER 156 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 S D F+QI L + H H D+K N+L+ G +A DFG S Sbjct: 157 PRLSERDARHFFRQIVSALHYCHQNG--IVHRDLKLENILLDAN-GNIKIA---DFGLSN 210 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 ++ C +P + +PE+ + + + D WSLG LY +++ Sbjct: 211 -----------LYHKGKFLQTFCGSPLYASPEIVNGKPY--VGPEVDSWSLGVLLYILVH 257 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDI 1077 G PF+ G+ +L I N + PP P + W+L P R + D+ Sbjct: 258 GTMPFD---GQDHKTLVKQISNGAYR-----EPPKPSDACGLIRWLLMVNPTRRATLEDV 309 Query: 1078 LLH 1086 H Sbjct: 310 ASH 312
>Q9Z2B9:KS6A4_MOUSE Ribosomal protein S6 kinase alpha-4 - Mus musculus (Mouse)| Length = 773 Score = 61.2 bits (147), Expect = 9e-09 Identities = 60/213 (28%), Positives = 97/213 (45%), Gaps = 1/213 (0%) Frame = +1 Query: 325 VLIQSREQLDLVKEEIRVSSLF-NHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDG 501 V I SR + + E+ L +HPN++ L H ++ D H YL+ + G Sbjct: 439 VKILSRRLEENTQREVAALRLCQSHPNVVNL--HEVLH------DQLH-TYLVLELLRGG 489 Query: 502 TLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQ 681 L ++ +K +S + +I + + + MH + H D+KP N+L Sbjct: 490 ELLEHIR----KKRLFSESEASQILRSLVSAVSFMHE-EAGVVHRDLKPENILYADDTPG 544 Query: 682 APLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDI 861 AP+ ++DFG +R +R +S A +Q + + APEL + DE D+ Sbjct: 545 APVK-IIDFGFAR-----LRPQSPAEPMQ---TPCFTLQYAAPELL---AQQGYDESCDL 592 Query: 862 WSLGCTLYAIMYGVSPFEYALGESGGSLQLAIM 960 WSLG LY ++ G PF+ A G+ G S IM Sbjct: 593 WSLGVILYMMLSGQVPFQGASGQGGQSQAAEIM 625 Score = 48.1 bits (113), Expect = 8e-05 Identities = 71/307 (23%), Positives = 122/307 (39%), Gaps = 8/307 (2%) Frame = +1 Query: 109 GCSISGLNALYDAATGGGDVWINERRFRVLRQIGEGGFAFVYLVKE---HDASSDAARDR 279 GC++ + +A G + ++ F +L+ +G G + V+LV++ HDA Sbjct: 9 GCAVE--LQITEANLTGHEEKVSVENFALLKVLGTGAYGKVFLVRKTGGHDAGK------ 60 Query: 280 HPSHVSGDGTYAMKKV----LIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKST 447 YAMK + L+Q + + + E V L L L +A Sbjct: 61 ---------LYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAF------ 105 Query: 448 QGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPY 627 + +L+ G +F + +++++ +V +I L+H+H L Y Sbjct: 106 --QTDAKLHLILDYVSGGEMFTHLY----QRQYFKEAEVRVYGGEIVLALEHLHKLGIIY 159 Query: 628 AHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSA-PFR 804 D+K NVL+ + L DFG S+ + + R+ + C + Sbjct: 160 --RDLKLENVLLDSEGH----IVLTDFGLSKEFLTEEKERTFSF---------CGTIEYM 204 Query: 805 APELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQ 984 APE+ S A + D WSLG L+ ++ G SPF E + Q + LK Sbjct: 205 APEI--IRSKAGHGKAVDWWSLGILLFELLTGASPFTL---EGERNTQAEVSRRILKC-- 257 Query: 985 LPSPPYP 1005 SPP+P Sbjct: 258 --SPPFP 262
>Q9WUT3:KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 - Mus musculus (Mouse)| Length = 733 Score = 61.2 bits (147), Expect = 9e-09 Identities = 69/300 (23%), Positives = 118/300 (39%) Frame = +1 Query: 232 YLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLP 411 Y +KE + + H + D YA+K + R+ + ++ +R HPN Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPSEEIEILLRYGQ---HPN--- 468 Query: 412 LLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICE 591 II +K D + YL+ + G L D R+ +S + + I Sbjct: 469 -----IITLKDVYDDGKY-VYLVMELMRGGELLDRIL----RQRCFSEREASDVLYTIAR 518 Query: 592 GLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQE 771 + ++HS H D+KP N+L + G + DFG ++ Q+R+ + L Sbjct: 519 TMDYLHSQG--VVHRDLKPSNILYMDESGNPESIRICDFGFAK----QLRAENGLLMTPC 572 Query: 772 WAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQL 951 + A F APE+ + D D+WSLG LY ++ G +PF ++ + Sbjct: 573 YTAN-----FVAPEVLKRQGY---DAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILA 624 Query: 952 AIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP*SQLA 1131 I + + DA V+ ML P R +L H + +Y +QL+ Sbjct: 625 RIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWIVNREYLSQNQLS 684 Score = 53.5 bits (127), Expect = 2e-06 Identities = 68/273 (24%), Positives = 117/273 (42%), Gaps = 3/273 (1%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 +F +L+ +G+G + V+LV++ SDA + YAMK + + + D V+ Sbjct: 58 QFELLKVLGQGSYGKVFLVRKV-TGSDAGQ-----------LYAMKVLKKATLKVRDRVR 105 Query: 364 EEIRVSSL--FNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 ++ L NHP ++ L H T+G + YL+ G LF S+ Sbjct: 106 SKMERDILAEVNHPFIVKL--HYAF---QTEG----KLYLILDFLRGGDLFTRL----SK 152 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + ++ DV ++ L H+H L Y D+KP N+L+ ++G + DFG S Sbjct: 153 EVMFTEEDVKFYLAELALALDHLHGLGIIY--RDLKPENILLD-EEGHIKIT---DFGLS 206 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSA-PFRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 + A + + A C + APE+ + H + D WS G ++ ++ Sbjct: 207 KEATDHDKR----------AYSFCGTIEYMAPEVVNRRGHT---QSADWWSFGVLMFEML 253 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPS 993 G PF+ G+ I+ A+L PQ S Sbjct: 254 TGSLPFQ---GKDRKETMALILKAKLGMPQFLS 283
>Q6DGS3:KCC2D_DANRE Calcium/calmodulin-dependent protein kinase type II delta chain -| Danio rerio (Zebrafish) (Brachydanio rerio) Length = 493 Score = 61.2 bits (147), Expect = 9e-09 Identities = 62/245 (25%), Positives = 100/245 (40%), Gaps = 3/245 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK- 363 +++ ++G+G F+ V R +S YA K + + D K Sbjct: 13 YQLFEELGKGAFSVV---------------RRCVKISSGQEYAAKIINTKKLSARDHQKL 57 Query: 364 -EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRK 540 E R+ L HPN++ L D S + H YL+F + G LF++ + Sbjct: 58 EREARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTGGELFEDIVA----R 104 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLV-TRQKGQAPLATLMDFGSS 717 E+YS D QQI E + H H H D+KP N+L+ ++ KG A L DFG + Sbjct: 105 EYYSEADASHCIQQILESVHHCHV--NGIVHRDLKPENLLLASKMKGAA--VKLADFGLA 160 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 + Q W + + +PE+ + + D+W+ G LY ++ Sbjct: 161 IEVQGD---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVDMWACGVILYILLV 208 Query: 898 GVSPF 912 G PF Sbjct: 209 GYPPF 213
>Q5RD00:AAPK2_PONPY 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Pongo| pygmaeus (Orangutan) Length = 552 Score = 61.2 bits (147), Expect = 9e-09 Identities = 72/253 (28%), Positives = 107/253 (42%), Gaps = 1/253 (0%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 I+S + + +K EI+ LF HP+++ L V ST D+ +++ G LF Sbjct: 52 IRSLDVVGKIKREIQNLKLFRHPHIIKLYQ-----VISTPTDF----FMVMEYVSGGELF 102 Query: 511 DNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 D +E ++ R+FQQI + + H H D+KP NVL+ Sbjct: 103 DYICKHGRVEE----MEARRLFQQILSAVDYCHR--HMVVHRDLKPENVLLDAHMN---- 152 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWS 867 A + DFG S I S E LR C +P + APE+ +A + DIWS Sbjct: 153 AKIADFGLSN-----IMSDGEFLRTS------CGSPNYAAPEVISGRLYAGPE--VDIWS 199 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 G LYA++ G PF+ E +L I P+ + ++ + MLQ Sbjct: 200 CGVILYALLCGTLPFD---DEHVPTLFKKIRGGVFYIPEYLN----RSVATLLMHMLQVD 252 Query: 1048 PAMRPHINDILLH 1086 P R I DI H Sbjct: 253 PLKRATIKDIREH 265
>Q5R4F3:TAOK3_PONPY Serine/threonine-protein kinase TAO3 - Pongo pygmaeus (Orangutan)| Length = 898 Score = 60.8 bits (146), Expect = 1e-08 Identities = 78/307 (25%), Positives = 124/307 (40%), Gaps = 4/307 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E F L +IG G F VY A + H + V A+KK+ Q+ E+ Sbjct: 21 EELFIGLHEIGHGSFGAVYF----------ATNAHTNEV-----VAIKKMSYSGKQTHEK 65 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E++ HPN + ++ +K H A+L+ L G+ D ++ Sbjct: 66 WQDILKEVKFLRQLKHPNTI---EYKGCYLKE------HTAWLVMEYCL-GSASD---LL 112 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + K+ +++ I GL ++HS H D+K GN+L+T + GQ LA DF Sbjct: 113 EVHKKPLQEVEIAAITHGALHGLAYLHS--HALIHRDIKAGNILLT-EPGQVKLA---DF 166 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLY 885 GS+ A A P+ APE+ D + D+WSLG T Sbjct: 167 GSASVASP--------------ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCI 212 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + P + + + AQ P L S + D+ +FV + LQ P RP Sbjct: 213 ELAER-KPALFNMNAMSALYHI----AQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPT 267 Query: 1066 INDILLH 1086 ++L H Sbjct: 268 SAELLRH 274
>P13234:KCC4_RAT Calcium/calmodulin-dependent protein kinase type IV - Rattus| norvegicus (Rat) Length = 474 Score = 60.8 bits (146), Expect = 1e-08 Identities = 64/259 (24%), Positives = 104/259 (40%), Gaps = 9/259 (3%) Frame = +1 Query: 163 DVWINERR-------FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMK 321 D WI+ + F V ++G G + VY K+ YA+K Sbjct: 27 DYWIDGSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKP---------------YALK 71 Query: 322 KVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDG 501 +++ +V+ EI V +HPN++ L + + E L+ + G Sbjct: 72 --VLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIF---------ETPTEISLVLELVTGG 120 Query: 502 TLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQ 681 LFD K +YS D +QI E + ++H + H D+KP N+L Sbjct: 121 ELFDRIV----EKGYYSERDAADAVKQILEAVAYLH--ENGIVHRDLKPENLLYATPAPD 174 Query: 682 APLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPE-LWDCPSHADIDERT 855 APL + DFG S+ +Q+ ++ C P + APE L C ++D Sbjct: 175 APLK-IADFGLSKIVEHQVLMKTV-----------CGTPGYCAPEILRGCAYGPEVD--- 219 Query: 856 DIWSLGCTLYAIMYGVSPF 912 +WS+G Y ++ G PF Sbjct: 220 -MWSVGIITYILLCGFEPF 237
>Q5ZKI0:KCC2D_CHICK Calcium/calmodulin-dependent protein kinase type II delta chain -| Gallus gallus (Chicken) Length = 479 Score = 60.8 bits (146), Expect = 1e-08 Identities = 52/198 (26%), Positives = 85/198 (42%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILESVNHCHL--NGIVHRDLKPENLLLA-SKS 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + + Q W + + +PE+ + + D Sbjct: 149 KGAAVKLADFGLAIEVQGE---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPF 912 +W+ G LY ++ G PF Sbjct: 197 MWACGVILYILLVGYPPF 214
>O43293:DAPK3_HUMAN Death-associated protein kinase 3 - Homo sapiens (Human)| Length = 454 Score = 60.8 bits (146), Expect = 1e-08 Identities = 61/254 (24%), Positives = 112/254 (44%), Gaps = 2/254 (0%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQL-- 351 E + + ++G G FA V ++ + A + K+ L SR + Sbjct: 10 EDHYEMGEELGSGQFAIVRKCRQKGTGKEYA-----------AKFIKKRRLSSSRRGVSR 58 Query: 352 DLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQ 531 + ++ E+ + HPN++ L H I K+ + L+ + G LFD A + Sbjct: 59 EEIEREVNILREIRHPNIITL--HDIFENKT-------DVVLILELVSGGELFDFLAEKE 109 Query: 532 SRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFG 711 S E + + +QI +G+ ++HS AH D+KP N+++ + P L+DFG Sbjct: 110 SLTED----EATQFLKQILDGVHYLHS--KRIAHFDLKPENIMLLDKNVPNPRIKLIDFG 163 Query: 712 SSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAI 891 + ++I + +E + + F APE+ ++ + D+WS+G Y + Sbjct: 164 IA----HKIEAGNEFKNI------FGTPEFVAPEI---VNYEPLGLEADMWSIGVITYIL 210 Query: 892 MYGVSPFEYALGES 933 + G SPF LGE+ Sbjct: 211 LSGASPF---LGET 221
>P34208:CHK1_SCHPO Serine/threonine-protein kinase chk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 496 Score = 60.8 bits (146), Expect = 1e-08 Identities = 72/309 (23%), Positives = 127/309 (41%), Gaps = 9/309 (2%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAAR---DRHPSHVSGDGTYAMKKVLIQSREQLDL 357 + + R+IG G FA V L + +A A + +H + G +A + Sbjct: 10 YHIGREIGTGAFASVRLCYDDNAKIYAVKFVNKKHATSCMNAGVWARR------------ 57 Query: 358 VKEEIRVSSLFN-HPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD----NAA 522 + EI++ L N H N++ H ++ Q W ++ G LFD + Sbjct: 58 MASEIQLHKLCNGHKNII----HFYNTAENPQWRW-----VVLEFAQGGDLFDKIEPDVG 108 Query: 523 VMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLM 702 + + +FY F Q+ EG+ MHS AH D+KP N+L+ + Sbjct: 109 IDEDVAQFY--------FAQLMEGISFMHS--KGVAHRDLKPENILLDYNGN----LKIS 154 Query: 703 DFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTL 882 DFG + + + +S L + S P+ APE+ + + D+WS G L Sbjct: 155 DFGFA--SLFSYKGKSRLLN-----SPVGSPPYAAPEI----TQQYDGSKVDVWSCGIIL 203 Query: 883 YAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQL-PSPPYPDALHKFVTWMLQPQPAMR 1059 +A++ G +P++ A+ +G L + Q + P P + +T ML+ P R Sbjct: 204 FALLLGNTPWDEAISNTGDYL---LYKKQCERPSYHPWNLLSPGAYSIITGMLRSDPFKR 260 Query: 1060 PHINDILLH 1086 + ++ H Sbjct: 261 YSVKHVVQH 269
>Q43531:CCAMK_LILLO Calcium and calcium/calmodulin-dependent serine/threonine-protein| kinase - Lilium longiflorum (Trumpet lily) Length = 520 Score = 60.8 bits (146), Expect = 1e-08 Identities = 62/237 (26%), Positives = 96/237 (40%) Frame = +1 Query: 376 VSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSV 555 V + HPN++ L D + G +L+ + G LFD V Q R YS Sbjct: 95 VEDVSPHPNVIHLHD----VYEDANG-----VHLVLELCSGGELFDRI-VAQDR---YSE 141 Query: 556 LDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQ 735 + + QQI GL +H H D+KP N L Q+ ++ L +MDFG S Sbjct: 142 SEAAEVVQQIASGLAALHK--STIIHRDLKPENCLFLNQEKRSTLK-IMDFGLS-----S 193 Query: 736 IRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE 915 + ++ + A S + +PE S + +D+WSLG LY ++ G PF Sbjct: 194 VEDFTDPI-----VALFGSIDYVSPEAL---SQRQVSSASDMWSLGVILYILLSGCPPFH 245 Query: 916 YALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 S Q I+ + + + ++ +L P RP ND+L H Sbjct: 246 ---APSNREKQQRILAGDFSFEEHTWKTITSSAKDLISSLLSVDPYKRPTANDLLKH 299
>Q8BYC6:TAOK3_MOUSE Serine/threonine-protein kinase TAO3 - Mus musculus (Mouse)| Length = 898 Score = 60.5 bits (145), Expect = 2e-08 Identities = 80/309 (25%), Positives = 124/309 (40%), Gaps = 6/309 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E F L +IG G F VY A + H + V A+KK+ Q+ E+ Sbjct: 21 EELFIDLHEIGHGSFGAVYF----------ATNAHTNEV-----VAVKKMSYSGKQTHEK 65 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E++ HPN + ++ +K H A+L+ L G+ D ++ Sbjct: 66 WQDILKEVKFLQQLKHPNTI---EYKGCYLKE------HTAWLVMEYCL-GSASD---LL 112 Query: 529 QSRKEFYSVLDVLRIFQQICEGLK--HMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLM 702 + K+ +++ I +GL H HSL H D+K GN+L+T + GQ LA Sbjct: 113 EVHKKPLQEVEIAAITHGALQGLAYLHFHSL----IHRDIKAGNILLT-EPGQVKLA--- 164 Query: 703 DFGSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCT 879 DFGS+ A A P+ APE+ D + DIWSLG T Sbjct: 165 DFGSASMASP--------------ANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGIT 210 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 + P + ++ AQ P L S + D+ +FV + L P R Sbjct: 211 CIELAERKPPL-----FNMNAMSALYHIAQNDSPTLQSREWTDSFRRFVDYCLHKIPQER 265 Query: 1060 PHINDILLH 1086 P ++L H Sbjct: 266 PAAVELLRH 274
>Q9I9E0:TAOK3_CHICK Serine/threonine-protein kinase TAO3 - Gallus gallus (Chicken)| Length = 898 Score = 60.5 bits (145), Expect = 2e-08 Identities = 78/307 (25%), Positives = 124/307 (40%), Gaps = 4/307 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E F L +IG G F VY A + H + V A+KK+ Q+ E+ Sbjct: 21 EEIFVGLHEIGHGSFGAVYF----------ATNSHTNEV-----VAVKKMSYSGKQTNEK 65 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E++ HPN + ++ +K H A+L+ L G+ D ++ Sbjct: 66 WQDIIKEVKFLQQLKHPNTI---EYKGCYLKE------HTAWLVMEYCL-GSASD---ML 112 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + K+ +++ I +GL ++HS H D+K GN+L+T + GQ LA DF Sbjct: 113 EVHKKPLQEVEIAAITHGALQGLAYLHSHCK--IHRDIKAGNILLT-EPGQVKLA---DF 166 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLY 885 GS+ + A P+ APE+ D + D+WSLG T Sbjct: 167 GSAS--------------IVSPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCI 212 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + P + ++ AQ P L S + D+ FV + LQ P RP Sbjct: 213 ELAERKPPL-----FNMNAMSALYHIAQNDSPTLQSNEWSDSFRGFVDYCLQKIPQERPS 267 Query: 1066 INDILLH 1086 D+L H Sbjct: 268 SADLLRH 274
>P84199:NEK1_CAEEL Serine/threonine-protein kinase D1044.8 - Caenorhabditis elegans| Length = 959 Score = 60.5 bits (145), Expect = 2e-08 Identities = 69/318 (21%), Positives = 131/318 (41%), Gaps = 19/318 (5%) Frame = +1 Query: 172 INERR--------FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKV 327 +NERR + +L Q+G G F VY V++ S +P+ + A+K++ Sbjct: 418 VNERRQAVGEVGEYELLDQLGAGAFGCVYTVRKKAQS----HSENPAKL-----LALKEI 468 Query: 328 LIQSREQL-------DLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFP 486 + + D++ E + HPN++ + I V++ H Y++ Sbjct: 469 FMTNLNDRESDKSFGDMISEVKIIKQQLRHPNIVR---YRRIFVEN------HRLYIVMD 519 Query: 487 VHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVT 666 + +L D M+ +K + + + Q+ L+++H + H D+KP N+++T Sbjct: 520 LIQGCSLRDLIITMKEKKGNFEEKKIWAMVVQMMLALRYLHK-EKQIVHRDLKPNNIMMT 578 Query: 667 RQKGQAPLATLMDFG-SSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPS---H 834 + + DFG + + ++S + + ++ CP + Sbjct: 579 TDER----VVITDFGLAKQKGPEYLKSAAGTI------------------IYSCPEIVQN 616 Query: 835 ADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDAL 1014 E+ DIWS GC +Y M + P + S L LA+ + K+ L + + D L Sbjct: 617 LPYGEKADIWSFGCCIYE-MCQLQP----VFHSTNMLTLAMQIVEAKYDPL-NEMWSDDL 670 Query: 1015 HKFVTWMLQPQPAMRPHI 1068 +T L P P+ RP I Sbjct: 671 RFLITSCLAPDPSARPDI 688
>Q8C0Q4:NEK11_MOUSE Serine/threonine-protein kinase Nek11 - Mus musculus (Mouse)| Length = 628 Score = 60.5 bits (145), Expect = 2e-08 Identities = 74/304 (24%), Positives = 121/304 (39%), Gaps = 4/304 (1%) Frame = +1 Query: 181 RRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLV 360 RR+ + +++G G F VYLV + A G+ +K++ + + V Sbjct: 28 RRYVLQQKLGSGSFGTVYLVSDKKAKP------------GEELKVLKEISVGELNPNETV 75 Query: 361 KEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRK 540 + + LL L H I V+ E + + + +G D +Q K Sbjct: 76 QANVEAQ-------LLSRLHHPAI-VRFHASFMEQETFCIITEYCEGRDLDYR--IQEYK 125 Query: 541 EFYSVL---DVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFG 711 E V ++ F Q+ G+ +MH + H D+K N+ + L + DFG Sbjct: 126 EAGKVFAENQIVEWFIQLLLGVDYMH--ERRILHRDLKSKNIFLKNN-----LLKIGDFG 178 Query: 712 SSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAI 891 SR + S L H +P + H D ++DIWSL C I Sbjct: 179 VSR-----LLMGSCELATTLTGTPHYMSP-------EALKHQGYDAKSDIWSLAC----I 222 Query: 892 MYGVSPFEYALGESGGSLQLAIMN-AQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHI 1068 +Y + ++A +G S ++N + K P LP YP L+ + ML P++RP Sbjct: 223 LYEMCCLDHAF--AGSSFLSVVLNIVEGKTPSLPD-RYPRELNTIMERMLNKSPSLRPSA 279 Query: 1069 NDIL 1080 DIL Sbjct: 280 ADIL 283
>Q1DB00:MASK_MYXXD Tyrosine-protein kinase masK - Myxococcus xanthus (strain DK 1622)| Length = 646 Score = 60.5 bits (145), Expect = 2e-08 Identities = 65/299 (21%), Positives = 125/299 (41%), Gaps = 10/299 (3%) Frame = +1 Query: 193 VLRQIGEGGFAFVYLVKEHDASS---DAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++R++ EGG A ++L K A + R H++ + + +++ + Sbjct: 27 LVRKLAEGGMAEIFLAKLLGADGFERNVVIKRMLPHLTNNPDF------------VEMFR 74 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 +E R+++ HPN++ + + ++ Y + +L G F + RK Sbjct: 75 DEARLAAKLAHPNIVQIQELG----------FAEGCYYICMEYLAGEDFSTTLRLAGRKR 124 Query: 544 FYSVLDV-LRIFQQICEGLKHMHSLDPP------YAHNDVKPGNVLVTRQKGQAPLATLM 702 Y L V LR+ GL H H D+ P N+ +T Q GQ + + Sbjct: 125 HYVPLPVVLRVLIDAARGLHFAHEFTNEAGQPLNVVHRDISPSNLYLTYQ-GQVKV---L 180 Query: 703 DFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTL 882 DFG ++ + +R+ ++ + + APE ++D R DI++LG +L Sbjct: 181 DFGIAKAESRLVNTRTGVVKGKYM--------YMAPEQ---ARGKEVDRRADIFALGVSL 229 Query: 883 YAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 Y + V PF E+ ++ A++ +LK P+ P P+ L + + +P R Sbjct: 230 YEALTHVRPFS---RENDLAVLNALLQGELKPPRELRPDLPEELEAILLKAMAFKPEDR 285
>P49071:MAPK2_DROME MAP kinase-activated protein kinase 2 - Drosophila melanogaster| (Fruit fly) Length = 359 Score = 60.5 bits (145), Expect = 2e-08 Identities = 51/177 (28%), Positives = 77/177 (43%), Gaps = 3/177 (1%) Frame = +1 Query: 559 DVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQI 738 + +I +IC + ++HS D AH D+KP N+L T + A L L DFG ++ Sbjct: 118 EAAQIMHEICAAVDYLHSRD--IAHRDLKPENLLYTTTQPNATLK-LTDFGFAKETFTSY 174 Query: 739 RSRSEALRLQEWAAEHCSAPFR-APELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPF- 912 ++ C P+ APE+ + D+ DIWSLG +Y IM G PF Sbjct: 175 TLQTP-----------CYTPYYVAPEVLGPEKY---DKSCDIWSLGVVMYIIMCGFPPFY 220 Query: 913 -EYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 + L S G ++ I Q +P A + ML P+ R I D++ Sbjct: 221 SNHGLAISPG-MKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVI 276
>P08413:KCC2B_RAT Calcium/calmodulin-dependent protein kinase type II beta chain -| Rattus norvegicus (Rat) Length = 542 Score = 60.5 bits (145), Expect = 2e-08 Identities = 63/256 (24%), Positives = 100/256 (39%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L H N++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHSNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H + H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILEAVLHCHQMG--VVHRDLKPENLLLA-SKC 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + Q W + + +PE+ ++ + D Sbjct: 149 KGAAVKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKEAYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWML 1038 IW+ G LY ++ G PF E L I +P + ML Sbjct: 197 IWACGVILYILLVGYPPF---WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253 Query: 1039 QPQPAMRPHINDILLH 1086 PA R ++ L H Sbjct: 254 TINPAKRITAHEALKH 269
>P28652:KCC2B_MOUSE Calcium/calmodulin-dependent protein kinase type II beta chain - Mus| musculus (Mouse) Length = 542 Score = 60.5 bits (145), Expect = 2e-08 Identities = 63/256 (24%), Positives = 100/256 (39%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L H N++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHSNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H + H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILEAVLHCHQMG--VVHRDLKPENLLLA-SKC 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + Q W + + +PE+ ++ + D Sbjct: 149 KGAAVKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKEAYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWML 1038 IW+ G LY ++ G PF E L I +P + ML Sbjct: 197 IWACGVILYILLVGYPPF---WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253 Query: 1039 QPQPAMRPHINDILLH 1086 PA R ++ L H Sbjct: 254 TINPAKRITAHEALKH 269
>Q13554:KCC2B_HUMAN Calcium/calmodulin-dependent protein kinase type II beta chain - Homo| sapiens (Human) Length = 664 Score = 60.5 bits (145), Expect = 2e-08 Identities = 63/256 (24%), Positives = 100/256 (39%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L H N++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHSNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H + H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILEAVLHCHQMG--VVHRDLKPENLLLA-SKC 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + Q W + + +PE+ ++ + D Sbjct: 149 KGAAVKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKEAYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWML 1038 IW+ G LY ++ G PF E L I +P + ML Sbjct: 197 IWACGVILYILLVGYPPF---WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253 Query: 1039 QPQPAMRPHINDILLH 1086 PA R ++ L H Sbjct: 254 TINPAKRITAHEALKH 269
>Q3MHJ9:KCC2B_BOVIN Calcium/calmodulin-dependent protein kinase type II beta chain - Bos| taurus (Bovine) Length = 542 Score = 60.5 bits (145), Expect = 2e-08 Identities = 63/256 (24%), Positives = 100/256 (39%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L H N++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHSNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H + H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILEAVLHCHQMG--VVHRDLKPENLLLA-SKC 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + Q W + + +PE+ ++ + D Sbjct: 149 KGAAVKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKEAYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWML 1038 IW+ G LY ++ G PF E L I +P + ML Sbjct: 197 IWACGVILYILLVGYPPF---WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253 Query: 1039 QPQPAMRPHINDILLH 1086 PA R ++ L H Sbjct: 254 TINPAKRIMAHEALKH 269
>O75385:ULK1_HUMAN Serine/threonine-protein kinase ULK1 - Homo sapiens (Human)| Length = 1050 Score = 60.1 bits (144), Expect = 2e-08 Identities = 66/260 (25%), Positives = 112/260 (43%), Gaps = 7/260 (2%) Frame = +1 Query: 157 GGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ 336 GG + + F IG G FA V+ + R++H V+ KK L + Sbjct: 6 GGTETVGKFEFSRKDLIGHGAFAVVFKGRH--------REKHDLEVAVK--CINKKNLAK 55 Query: 337 SREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDN 516 S+ L+ +EI++ H N++ L D +A + YL+ G L D Sbjct: 56 SQT---LLGKEIKILKELKHENIVALYDFQEMA---------NSVYLVMEYCNGGDLADY 103 Query: 517 AAVMQSRKEFYSVLDVLRIF-QQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAP-- 687 M++ E D +R+F QQI ++ +HS H D+KP N+L++ G+ Sbjct: 104 LHAMRTLSE-----DTIRLFLQQIAGAMRLLHSKG--IIHRDLKPQNILLSNPAGRRANP 156 Query: 688 ---LATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERT 855 + DFG +R ++ + AA C +P + APE+ + D + Sbjct: 157 NSIRVKIADFGFARYLQSNMM-----------AATLCGSPMYMAPEVIMSQHY---DGKA 202 Query: 856 DIWSLGCTLYAIMYGVSPFE 915 D+WS+G +Y + G +PF+ Sbjct: 203 DLWSIGTIVYQCLTGKAPFQ 222
>Q03428:NRKB_TRYBB Putative serine/threonine-protein kinase B - Trypanosoma brucei| brucei Length = 431 Score = 60.1 bits (144), Expect = 2e-08 Identities = 67/266 (25%), Positives = 108/266 (40%), Gaps = 8/266 (3%) Frame = +1 Query: 301 DGTYAMKKVLI---QSREQLDLVKEEIRVSSLFNHPNLLPLL-DHAIIAVKSTQGDWSHE 468 DG+ + KV+ SR + EI+ + NHPN++ + DH ++ Sbjct: 42 DGSLCVAKVMDLSKMSRRDKRYAQSEIKYPTNCNHPNIIRYIEDHE-----------END 90 Query: 469 AYLLFPVHLDGTLFDNAAVMQSRKE--FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDV 642 L+ D D + ++ + L +F Q+C L ++HS H D+ Sbjct: 91 RLLIVMEFADSGNLDEQIKPWGTGDARYFQEHEALFLFLQLCLALDYIHS--HKMLHRDI 148 Query: 643 KPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFR-APELW 819 K NVL+T L L DFG S + + A+ C P+ APELW Sbjct: 149 KSANVLLT----STGLVKLGDFGFSHQYEDTVSGVV--------ASTFCGTPYYLAPELW 196 Query: 820 DCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSP- 996 + + +++ D+WSLG LY IM PF S +L+ +M+ L P P Sbjct: 197 N---NLRYNKKADVWSLGVLLYEIMGMKKPF------SASNLK-GLMSKVLAGTYAPLPD 246 Query: 997 PYPDALHKFVTWMLQPQPAMRPHIND 1074 + + V +L P RP + + Sbjct: 247 SFSSEFKRVVDGILVADPNDRPSVRE 272
>O75676:KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 - Homo sapiens (Human)| Length = 772 Score = 60.1 bits (144), Expect = 2e-08 Identities = 53/211 (25%), Positives = 93/211 (44%) Frame = +1 Query: 328 LIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTL 507 ++ R + + +E + +HPN ++ + D H YL+ + G L Sbjct: 441 ILSRRLEANTQREVAALRLCQSHPN--------VVNLHEVHHDQLH-TYLVLELLRGGEL 491 Query: 508 FDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAP 687 ++ +K +S + +I + + + MH + H D+KP N+L AP Sbjct: 492 LEHIR----KKRHFSESEASQILRSLVSAVSFMHE-EAGVVHRDLKPENILYADDTPGAP 546 Query: 688 LATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWS 867 + ++DFG +R +R +S + +Q + + APEL + DE D+WS Sbjct: 547 VK-IIDFGFAR-----LRPQSPGVPMQ---TPCFTLQYAAPELL---AQQGYDESCDLWS 594 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIM 960 LG LY ++ G PF+ A G+ G S IM Sbjct: 595 LGVILYMMLSGQVPFQGASGQGGQSQAAEIM 625 Score = 47.0 bits (110), Expect = 2e-04 Identities = 70/308 (22%), Positives = 120/308 (38%), Gaps = 8/308 (2%) Frame = +1 Query: 142 DAATGGGDVWINERRFRVLRQIGEGGFAFVYLVKE---HDASSDAARDRHPSHVSGDGTY 312 +A G + ++ F +L+ +G G + V+LV++ HDA Y Sbjct: 18 EANLTGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGK---------------LY 62 Query: 313 AMKKV----LIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLL 480 AMK + L+Q + + + E V L L L +A + +L+ Sbjct: 63 AMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAF--------QTDAKLHLI 114 Query: 481 FPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVL 660 G +F + +++++ +V +I L+H+H L Y D+K NVL Sbjct: 115 LDYVSGGEMFTHLY----QRQYFKEAEVRVYGGEIVLALEHLHKLGIIY--RDLKLENVL 168 Query: 661 VTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSA-PFRAPELWDCPSHA 837 + + L DFG S+ + + R+ + C + APE+ S Sbjct: 169 LDSEGH----IVLTDFGLSKEFLTEEKERTFSF---------CGTIEYMAPEI--IRSKT 213 Query: 838 DIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALH 1017 + D WSLG L+ ++ G SPF E + Q + LK SPP+P + Sbjct: 214 GHGKAVDWWSLGILLFELLTGASPFTL---EGERNTQAEVSRRILKC----SPPFPPRIG 266 Query: 1018 KFVTWMLQ 1041 +LQ Sbjct: 267 PVAQDLLQ 274
>Q15349:KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 - Homo sapiens (Human)| Length = 733 Score = 60.1 bits (144), Expect = 2e-08 Identities = 69/300 (23%), Positives = 119/300 (39%) Frame = +1 Query: 232 YLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLP 411 Y +KE + + H + D YA+K + R+ + ++ +R HPN++ Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQ---HPNIIT 471 Query: 412 LLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICE 591 L D D YL+ + G L D R+ ++S + + I + Sbjct: 472 LKDVY---------DDGKFVYLVMELMRGGELLDRIL----RQRYFSEREASDVLCTITK 518 Query: 592 GLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQE 771 + ++HS H D+KP N+L + G + DFG ++ Q+R+ + L Sbjct: 519 TMDYLHSQG--VVHRDLKPSNILYRDESGSPESIRVCDFGFAK----QLRAGNGLLMTPC 572 Query: 772 WAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQL 951 + A F APE+ + D DIWSLG LY ++ G +PF ++ + Sbjct: 573 YTAN-----FVAPEVLKRQGY---DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILA 624 Query: 952 AIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLHVDKLVEKYSP*SQLA 1131 I + + DA V+ ML P R +L H + +Y +QL+ Sbjct: 625 RIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYLSPNQLS 684 Score = 55.8 bits (133), Expect = 4e-07 Identities = 70/273 (25%), Positives = 119/273 (43%), Gaps = 3/273 (1%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 +F +L+ +G+G + V+LV++ S DA + YAMK + + + D V+ Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGS-DAGQ-----------LYAMKVLKKATLKVRDRVR 105 Query: 364 EEIRVSSL--FNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 ++ L NHP ++ L H T+G + YL+ G LF S+ Sbjct: 106 SKMERDILAEVNHPFIVKL--HYAF---QTEG----KLYLILDFLRGGDLFTRL----SK 152 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + ++ DV ++ L H+HSL Y D+KP N+L+ ++G + DFG S Sbjct: 153 EVMFTEEDVKFYLAELALALDHLHSLGIIY--RDLKPENILLD-EEGHIKIT---DFGLS 206 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSA-PFRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 + EA+ + A C + APE+ + H + D WS G ++ ++ Sbjct: 207 K----------EAIDHDKRAYSFCGTIEYMAPEVVNRRGHT---QSADWWSFGVLMFEML 253 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPS 993 G PF+ G+ I+ A+L PQ S Sbjct: 254 TGSLPFQ---GKDRKETMALILKAKLGMPQFLS 283
>P15791:KCC2D_RAT Calcium/calmodulin-dependent protein kinase type II delta chain -| Rattus norvegicus (Rat) Length = 533 Score = 60.1 bits (144), Expect = 2e-08 Identities = 52/198 (26%), Positives = 84/198 (42%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILESVNHCHL--NGIVHRDLKPENLLLA-SKS 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + Q W + + +PE+ + + D Sbjct: 149 KGAAVKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPF 912 +W+ G LY ++ G PF Sbjct: 197 MWACGVILYILLVGYPPF 214
>O77708:KCC2D_RABIT Calcium/calmodulin-dependent protein kinase type II delta chain -| Oryctolagus cuniculus (Rabbit) Length = 533 Score = 60.1 bits (144), Expect = 2e-08 Identities = 52/198 (26%), Positives = 84/198 (42%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILESVNHCHL--NGIVHRDLKPENLLLA-SKS 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + Q W + + +PE+ + + D Sbjct: 149 KGAAVKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPF 912 +W+ G LY ++ G PF Sbjct: 197 MWACGVILYILLVGYPPF 214
>Q95266:KCC2D_PIG Calcium/calmodulin-dependent protein kinase type II delta chain -| Sus scrofa (Pig) Length = 499 Score = 60.1 bits (144), Expect = 2e-08 Identities = 52/198 (26%), Positives = 84/198 (42%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILESVNHCHL--NGIVHRDLKPENLLLA-SKS 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + Q W + + +PE+ + + D Sbjct: 149 KGAAVKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPF 912 +W+ G LY ++ G PF Sbjct: 197 MWACGVILYILLVGYPPF 214
>Q6PHZ2:KCC2D_MOUSE Calcium/calmodulin-dependent protein kinase type II delta chain -| Mus musculus (Mouse) Length = 499 Score = 60.1 bits (144), Expect = 2e-08 Identities = 52/198 (26%), Positives = 84/198 (42%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILESVNHCHL--NGIVHRDLKPENLLLA-SKS 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + Q W + + +PE+ + + D Sbjct: 149 KGAAVKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPF 912 +W+ G LY ++ G PF Sbjct: 197 MWACGVILYILLVGYPPF 214
>Q13557:KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II delta chain -| Homo sapiens (Human) Length = 499 Score = 60.1 bits (144), Expect = 2e-08 Identities = 52/198 (26%), Positives = 84/198 (42%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILESVNHCHL--NGIVHRDLKPENLLLA-SKS 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + Q W + + +PE+ + + D Sbjct: 149 KGAAVKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPF 912 +W+ G LY ++ G PF Sbjct: 197 MWACGVILYILLVGYPPF 214
>Q2HJF7:KCC2D_BOVIN Calcium/calmodulin-dependent protein kinase type II delta chain -| Bos taurus (Bovine) Length = 488 Score = 60.1 bits (144), Expect = 2e-08 Identities = 52/198 (26%), Positives = 84/198 (42%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E R+ L HPN++ L D S + H YL+F + Sbjct: 48 KKLSARDHQKLE---REARICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTG 95 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 G LF++ +E+YS D QQI E + H H H D+KP N+L+ K Sbjct: 96 GELFEDIVA----REYYSEADASHCIQQILESVNHCHL--NGIVHRDLKPENLLLA-SKS 148 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTD 858 + L DFG + + Q W + + +PE+ + + D Sbjct: 149 KGAAVKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPVD 196 Query: 859 IWSLGCTLYAIMYGVSPF 912 +W+ G LY ++ G PF Sbjct: 197 MWACGVILYILLVGYPPF 214
>Q9URT9:GSK31_SCHPO Protein kinase gsk31 - Schizosaccharomyces pombe (Fission yeast)| Length = 381 Score = 60.1 bits (144), Expect = 2e-08 Identities = 65/258 (25%), Positives = 108/258 (41%) Frame = +1 Query: 292 VSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEA 471 V G A+K+VL R + E+++ +HPN++ L+ A + D +H Sbjct: 45 VGTPGFIAVKRVLQDKRYK----NRELQIMRAISHPNIIKLI--AFFHTHNPSKDETHLC 98 Query: 472 YLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPG 651 LL ++ T+FD+ R++ L + Q+ L ++HS H D+KP Sbjct: 99 LLL--EYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHSTG--VCHRDIKPQ 154 Query: 652 NVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPS 831 N+LV + G + L DFGS A+ + S + CS +RAPEL + Sbjct: 155 NLLVDYKTG---ILKLCDFGS---AKVLVPSEPNVSYI-------CSRYYRAPELVFGAT 201 Query: 832 HADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDA 1011 H + D+WS C + + G F G+S + I+ L +P Y + Sbjct: 202 H--YTTKIDVWSAACVIAELFIGRPLFP---GDSSVEQLVEIIRV------LGTPSYHEI 250 Query: 1012 LHKFVTWMLQPQPAMRPH 1065 ++ P +RPH Sbjct: 251 SVMNPNYVNHSLPNVRPH 268
>P54646:AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Homo| sapiens (Human) Length = 552 Score = 60.1 bits (144), Expect = 2e-08 Identities = 71/253 (28%), Positives = 107/253 (42%), Gaps = 1/253 (0%) Frame = +1 Query: 331 IQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLF 510 I+S + + +K EI+ LF HP+++ L V ST D+ +++ G LF Sbjct: 52 IRSLDVVGKIKREIQNLKLFRHPHIIKLYQ-----VISTPTDF----FMVMEYVSGGELF 102 Query: 511 DNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 D +E ++ R+FQQI + + H H D+KP NVL+ Sbjct: 103 DYICKHGRVEE----MEARRLFQQILSAVDYCHR--HMVVHRDLKPENVLLDAHMN---- 152 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWS 867 A + DFG S + S E LR C +P + APE+ +A + DIWS Sbjct: 153 AKIADFGLSN-----MMSDGEFLRTS------CGSPNYAAPEVISGRLYAGPE--VDIWS 199 Query: 868 LGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 G LYA++ G PF+ E +L I P+ + ++ + MLQ Sbjct: 200 CGVILYALLCGTLPFD---DEHVPTLFKKIRGGVFYIPEYLN----RSVATLLMHMLQVD 252 Query: 1048 PAMRPHINDILLH 1086 P R I DI H Sbjct: 253 PLKRATIKDIREH 265
>O94804:STK10_HUMAN Serine/threonine-protein kinase 10 - Homo sapiens (Human)| Length = 968 Score = 59.7 bits (143), Expect = 3e-08 Identities = 75/304 (24%), Positives = 122/304 (40%), Gaps = 4/304 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 + ++ ++G+G F VY K + + AA K + +S E+L+ Sbjct: 36 WEIVGELGDGAFGKVYKAKNKETGALAAA---------------KVIETKSEEELEDYIV 80 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHL-DGTLFDNAAVMQSRKE 543 EI + + +HP ++ LL G + H+ L + G D A+M Sbjct: 81 EIEILATCDHPYIVKLL-----------GAYYHDGKLWIMIEFCPGGAVD--AIMLELDR 127 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 + + + +Q+ E L +HS H D+K GNVL+T + G LA DFG S Sbjct: 128 GLTEPQIQVVCRQMLEALNFLHS--KRIIHRDLKAGNVLMTLE-GDIRLA---DFGVSAK 181 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADI--DERTDIWSLGCTLYAIMY 897 ++ R + W A PE+ C + D D + DIWSLG TL M Sbjct: 182 NLKTLQKRDSFIGTPYWMA---------PEVVMCETMKDTPYDYKADIWSLGITLIE-MA 231 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSP-PYPDALHKFVTWMLQPQPAMRPHIND 1074 + P + L +++ + A+ P L +P + F+ L P RP Sbjct: 232 QIEPPHHEL----NPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQ 287 Query: 1075 ILLH 1086 +L H Sbjct: 288 LLEH 291
>P65726:PKNA_MYCTU Probable serine/threonine-protein kinase pknA - Mycobacterium| tuberculosis Length = 431 Score = 59.7 bits (143), Expect = 3e-08 Identities = 73/292 (25%), Positives = 120/292 (41%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R+R+ R I GG V+ +A +R V+ +K E ++ + Sbjct: 12 RYRLQRLIATGGMGQVW---------EAVDNRLGRRVA---VKVLKSEFSSDPEFIERFR 59 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E R +++ NHP + + D+ +S AYL+ + ++G ++ R Sbjct: 60 AEARTTAMLNHPGIASVHDYG----ESQMNGEGRTAYLVMEL-VNGEPLNSVLKRTGRLS 114 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 LD+L +Q L+ H+ H DVKPGN+L+T GQ + DFG Sbjct: 115 LRHALDML---EQTGRALQIAHAAG--LVHRDVKPGNILIT-PTGQVKIT---DFG---- 161 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 I +A + + +A + APE H D +D++SLG Y + G Sbjct: 162 ----IAKAVDAAPVTQTGMVMGTAQYIAPE--QALGH-DASPASDVYSLGVVGYEAVSGK 214 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 PF G+L +A+ + + P LP P P + + + L PAMR Sbjct: 215 RPF-----AGDGALTVAMKHIKEPPPPLP-PDLPPNVRELIEITLVKNPAMR 260
>P65727:PKNA_MYCBO Probable serine/threonine-protein kinase pknA - Mycobacterium bovis| Length = 431 Score = 59.7 bits (143), Expect = 3e-08 Identities = 73/292 (25%), Positives = 120/292 (41%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R+R+ R I GG V+ +A +R V+ +K E ++ + Sbjct: 12 RYRLQRLIATGGMGQVW---------EAVDNRLGRRVA---VKVLKSEFSSDPEFIERFR 59 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E R +++ NHP + + D+ +S AYL+ + ++G ++ R Sbjct: 60 AEARTTAMLNHPGIASVHDYG----ESQMNGEGRTAYLVMEL-VNGEPLNSVLKRTGRLS 114 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 LD+L +Q L+ H+ H DVKPGN+L+T GQ + DFG Sbjct: 115 LRHALDML---EQTGRALQIAHAAG--LVHRDVKPGNILIT-PTGQVKIT---DFG---- 161 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 I +A + + +A + APE H D +D++SLG Y + G Sbjct: 162 ----IAKAVDAAPVTQTGMVMGTAQYIAPE--QALGH-DASPASDVYSLGVVGYEAVSGK 214 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 PF G+L +A+ + + P LP P P + + + L PAMR Sbjct: 215 RPF-----AGDGALTVAMKHIKEPPPPLP-PDLPPNVRELIEITLVKNPAMR 260
>Q5F3L1:KS6A5_CHICK Ribosomal protein S6 kinase alpha-5 - Gallus gallus (Chicken)| Length = 789 Score = 59.7 bits (143), Expect = 3e-08 Identities = 52/212 (24%), Positives = 91/212 (42%), Gaps = 3/212 (1%) Frame = +1 Query: 289 HVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHE 468 H YA+K +I R + + +E + HPN ++ + D H Sbjct: 435 HKKTSQEYAVK--IISKRMEANTQREITALKLCEGHPN--------VVKLHEVYHDQLH- 483 Query: 469 AYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKP 648 +L+ + G L + +K+ +S + I +++ + HMH D H D+KP Sbjct: 484 TFLVMELLKGGELLERI----QKKQHFSETEASHIMRRLVSAVSHMH--DVGVVHRDLKP 537 Query: 649 GNVLVTRQKGQAPLATLMDFGSSR---PARNQIRSRSEALRLQEWAAEHCSAPFRAPELW 819 N+L T + + + ++DFG +R P +++ L + APEL+ Sbjct: 538 ENLLFTDETDNSEIK-IIDFGFARLKPPDNQPLKTPCFTLH------------YAAPELF 584 Query: 820 DCPSHADIDERTDIWSLGCTLYAIMYGVSPFE 915 + H DE D+WSLG LY ++ G PF+ Sbjct: 585 N---HNGYDESCDLWSLGVILYTMLSGQVPFQ 613 Score = 44.7 bits (104), Expect = 0.001 Identities = 65/290 (22%), Positives = 113/290 (38%), Gaps = 10/290 (3%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKE---HDASSDAARDRHPSHVSGDGTYAMKKV----LIQSRE 345 F +L+ +G G + V+LV++ HDA YAMK + ++Q + Sbjct: 39 FELLKVLGTGAYGKVFLVRKVSGHDAGK---------------LYAMKVLKKATIVQKAK 83 Query: 346 QLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAV 525 + + E +V L L +A + +L+ G LF + Sbjct: 84 TTEHTRTERQVLEHIRQSPFLVTLHYAF--------QTDTKLHLILDYINGGELFTHL-- 133 Query: 526 MQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMD 705 S++E +S +V +I L+H+H L Y D+K N+L+ L D Sbjct: 134 --SQRERFSENEVQIYIGEIVLALEHLHKLGIIY--RDIKLENILLDSDGH----VVLTD 185 Query: 706 FGSSRPARNQIRSRSEALRLQEWAAEHCSA-PFRAPELWDCPSHADIDERTDIWSLGCTL 882 FG S+ R A C + AP++ D+ D WS+G + Sbjct: 186 FGLSKEFLTDENER---------AYSFCGTIEYMAPDIVR-GGDTGHDKAVDWWSVGVLM 235 Query: 883 YAIMYGVSPFEYALGESGGSLQLA--IMNAQLKWPQLPSPPYPDALHKFV 1026 Y ++ G SPF GE +++ I+ ++ +PQ S D + + + Sbjct: 236 YELLTGASPFTVD-GEKNSQAEISRRILKSEPPYPQEMSALSKDIIQRLL 284
>Q21734:KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-1 - Caenorhabditis| elegans Length = 784 Score = 59.7 bits (143), Expect = 3e-08 Identities = 70/271 (25%), Positives = 119/271 (43%), Gaps = 4/271 (1%) Frame = +1 Query: 181 RRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAM---KKVLIQSREQL 351 R+F +L+ +G+G F V+LV++ R R HV YAM KK ++ R++ Sbjct: 102 RQFELLKVLGQGSFGKVFLVRK-------VRGRDSGHV-----YAMKVLKKATLKVRDR- 148 Query: 352 DLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQ 531 K E + + +HP ++ L +A T+G + YL+ G LF Sbjct: 149 QRTKLERNILAHISHPFIVK-LHYAF----QTEG----KLYLILDFLRGGDLFTRL---- 195 Query: 532 SRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFG 711 S++ ++ DV ++ L+H+HSL Y D+KP N+L+ + DFG Sbjct: 196 SKEVMFTEDDVKFYLAELTLALEHLHSLGIVY--RDLKPENILLDADGH----IKVTDFG 249 Query: 712 SSRPARNQIRSRSEALRLQEWAAEHC-SAPFRAPELWDCPSHADIDERTDIWSLGCTLYA 888 S+ EA+ ++ C + + APE+ + H+ D WSLG ++ Sbjct: 250 LSK----------EAIDSEKKTYSFCGTVEYMAPEVINRRGHS---MAADFWSLGVLMFE 296 Query: 889 IMYGVSPFEYALGESGGSLQLAIMNAQLKWP 981 ++ G PF+ G I+ A+L P Sbjct: 297 MLTGHLPFQ---GRDRNDTMTQILKAKLSMP 324 Score = 50.4 bits (119), Expect = 2e-05 Identities = 63/300 (21%), Positives = 119/300 (39%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 + +L +IG G + V H A R ++ + +KK + + E++D++ Sbjct: 454 YEILEKIGNGAHSVV-----HKCQMKATRRKYAVKI-------VKKAVFDATEEVDIL-- 499 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 +R S +H ++ L D + T Y++ + G L D + ++K Sbjct: 500 -LRHS---HHQFVVKLFD---VYEDETA------IYMIEELCEGGELLDK---LVNKKSL 543 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 S +V I + ++++HS AH D+ N+L + G ++DFG ++ Sbjct: 544 GSEKEVAAIMANLLNAVQYLHSQQ--VAHRDLTAANILFALKDGDPSSLRIVDFGFAK-- 599 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 Q R+ + L + A+ F APE+ + D D+WSLG L+ ++ G + Sbjct: 600 --QSRAENGMLMTPCYTAQ-----FVAPEVLRKQGY---DRSCDVWSLGVLLHTMLTGCT 649 Query: 907 PFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 PF ++ + + + ++ D V ML P R L H Sbjct: 650 PFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQH 709
>P08414:KCC4_MOUSE Calcium/calmodulin-dependent protein kinase type IV - Mus musculus| (Mouse) Length = 469 Score = 59.7 bits (143), Expect = 3e-08 Identities = 61/244 (25%), Positives = 99/244 (40%), Gaps = 2/244 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F V ++G G + VY K+ YA+K +++ +V+ Sbjct: 42 FEVESELGRGATSIVYRCKQKGTQKP---------------YALK--VLKKTVDKKIVRT 84 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 EI V +HPN++ L + + E L+ + G LFD K + Sbjct: 85 EIGVLLRLSHPNIIKLKEIF---------ETPTEISLVLELVTGGELFDRIV----EKGY 131 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 YS D +QI E + ++H + H D+KP N+L APL + DFG S+ Sbjct: 132 YSERDARDAVKQILEAVAYLH--ENGIVHRDLKPENLLYATPAPDAPLK-IADFGLSKIV 188 Query: 727 RNQIRSRSEALRLQEWAAEHCSAP-FRAPE-LWDCPSHADIDERTDIWSLGCTLYAIMYG 900 +Q+ ++ C P + APE L C ++D +WS+G Y ++ G Sbjct: 189 EHQVLMKTV-----------CGTPGYCAPEILRGCAYGPEVD----MWSVGIITYILLCG 233 Query: 901 VSPF 912 PF Sbjct: 234 FEPF 237
>Q12263:GIN4_YEAST Serine/threonine-protein kinase GIN4 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1142 Score = 59.7 bits (143), Expect = 3e-08 Identities = 65/253 (25%), Positives = 107/253 (42%), Gaps = 2/253 (0%) Frame = +1 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 ++ EI + L NHPN+L L D V T D YL+ G LF+ Sbjct: 78 IEREIIIMKLLNHPNVLRLYD-----VWETNTD----LYLVLEYAEKGELFNLLVERGPL 128 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 E + +R F+QI G+ + H+L H D+KP N+L+ + + DFG + Sbjct: 129 PEH----EAIRFFRQIIIGVSYCHALG--IVHRDLKPENLLLDHKYN----IKIADFGMA 178 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 + + + L C +P + APE+ + +D+WS G L+A++ Sbjct: 179 A-----LETEGKLLETS------CGSPHYAAPEIVSGIPYQGF--ASDVWSCGVILFALL 225 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPS-PPYPDALHKFVTWMLQPQPAMRPHIN 1071 G PF+ E G+++ ++ Q ++PS + +L P R Sbjct: 226 TGRLPFD----EEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTR 281 Query: 1072 DILLHVDKLVEKY 1110 DIL H L++KY Sbjct: 282 DILKH--PLLQKY 292
>Q4V7Q6:ULK3_XENLA Serine/threonine-protein kinase ULK3 - Xenopus laevis (African clawed| frog) Length = 468 Score = 59.3 bits (142), Expect = 4e-08 Identities = 75/305 (24%), Positives = 133/305 (43%), Gaps = 4/305 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F + ++G G +A VY A R R+ V + K + ++ ++ + Sbjct: 13 FILTEKLGSGSYATVY---------KAYRKRNAREVVAIKCVSKKSL---NKAAVENLLT 60 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 EI + +HP++L L D W + L + G D + +++R+ Sbjct: 61 EIEILKTVHHPHILELKDF----------QWDQDYIFLITEYCAGG--DLSRFIRTRRIL 108 Query: 547 YSVLDVLRIF-QQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 ++++F QQ+ LK +H + +H D+KP N+L++R P L DFG ++ Sbjct: 109 PE--RIVQVFLQQLASALKFLHEKN--ISHLDLKPQNILLSRL--DRPHLKLADFGFAQH 162 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 ++ +ALR S + APE+ C H D R D+WS+G LY ++G Sbjct: 163 MSSE--DAPQALR--------GSPLYMAPEMV-CSKH--YDARVDLWSVGVILYEALFGK 209 Query: 904 SPFEYALGESGGSLQLAIMNAQ-LKWPQLP--SPPYPDALHKFVTWMLQPQPAMRPHIND 1074 +PF +S L+ I++ + ++ P P SP D L + +LQ P R + Sbjct: 210 APF---ASKSFSELEEKILSHKTIELPTRPRLSPECRDLLQQ----LLQRDPDKRISFIE 262 Query: 1075 ILLHV 1089 H+ Sbjct: 263 FFAHL 267
>O08815:SLK_RAT STE20-like serine/threonine-protein kinase - Rattus norvegicus| (Rat) Length = 1206 Score = 59.3 bits (142), Expect = 4e-08 Identities = 60/237 (25%), Positives = 98/237 (41%), Gaps = 2/237 (0%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDL 357 E + ++ ++G+G F VY + + + AA K + +S E+L+ Sbjct: 31 EEFWEIIGELGDGAFGKVYKAQNKETNVLAAA---------------KVIDTKSEEELED 75 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 EI + + +HPN++ LLD + + ++L G + AVM Sbjct: 76 YMVEIDILASCDHPNIVKLLDAFY---------YENNLWILIEFCAGGAV---DAVMLEL 123 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + + + + +Q E L ++H D H D+K GN+L T G LA DFG S Sbjct: 124 ERPLTESQIQVVCKQTLEALNYLH--DNKIIHRDLKAGNILFTLD-GDIKLA---DFGVS 177 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHAD--IDERTDIWSLGCTL 882 I+ R + W APE+ C + D D + D+WSLG TL Sbjct: 178 AKNTRTIQRRDSFIGTPYW---------MAPEVVMCETSKDRPYDYKADVWSLGITL 225
>O54988:SLK_MOUSE STE20-like serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 1233 Score = 59.3 bits (142), Expect = 4e-08 Identities = 60/237 (25%), Positives = 98/237 (41%), Gaps = 2/237 (0%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDL 357 E + ++ ++G+G F VY + + + AA K + +S E+L+ Sbjct: 31 EEFWEIIGELGDGAFGKVYKAQNKETNVLAAA---------------KVIDTKSEEELED 75 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 EI + + +HPN++ LLD + + ++L G + AVM Sbjct: 76 YMVEIDILASCDHPNIVKLLDAFY---------YENNLWILIEFCAGGAV---DAVMLEL 123 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + + + + +Q E L ++H D H D+K GN+L T G LA DFG S Sbjct: 124 ERPLTESQIQVVCKQTLEALNYLH--DNKIIHRDLKAGNILFTLD-GDIKLA---DFGVS 177 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHAD--IDERTDIWSLGCTL 882 I+ R + W APE+ C + D D + D+WSLG TL Sbjct: 178 AKNTRTIQRRDSFIGTPYW---------MAPEVVMCETSKDRPYDYKADVWSLGITL 225
>P92937:CPK15_ARATH CBL-interacting serine/threonine-protein kinase 15 - Arabidopsis| thaliana (Mouse-ear cress) Length = 421 Score = 59.3 bits (142), Expect = 4e-08 Identities = 72/303 (23%), Positives = 119/303 (39%), Gaps = 4/303 (1%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMK---KVLIQSREQLD 354 R+ V + +G+G FA VY H H+ + A+K K I + Sbjct: 11 RYEVGKFLGQGTFAKVY---------------HARHLKTGDSVAIKVIDKERILKVGMTE 55 Query: 355 LVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 +K EI L HPN++ L H ++A KS + Y + G LF+ + + Sbjct: 56 QIKREISAMRLLRHPNIVEL--HEVMATKS-------KIYFVMEHVKGGELFNKVSTGKL 106 Query: 535 RKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGS 714 R++ + FQQ+ + HS H D+KP N+L+ + DFG Sbjct: 107 REDV-----ARKYFQQLVRAVDFCHSRG--VCHRDLKPENLLLDEHGN----LKISDFGL 155 Query: 715 SRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAI 891 S + S++ R C P + APE+ + + D+WS G L+ + Sbjct: 156 S--------ALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDGF--KADVWSCGVILFVL 205 Query: 892 MYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHIN 1071 + G PF + L I A++K+P +P + + +L P P R Sbjct: 206 LAGYLPFR---DSNLMELYKKIGKAEVKFPNWLAP----GAKRLLKRILDPNPNTRVSTE 258 Query: 1072 DIL 1080 I+ Sbjct: 259 KIM 261
>Q75CH3:ATG1_ASHGO Serine/threonine-protein kinase ATG1 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 972 Score = 59.3 bits (142), Expect = 4e-08 Identities = 73/287 (25%), Positives = 121/287 (42%), Gaps = 32/287 (11%) Frame = +1 Query: 151 TGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKV- 327 +GG V I R+ V ++IG G FA VY K H A S A G A+K V Sbjct: 6 SGGRPVAIVAERYVVEKEIGRGSFAVVY--KGHLADSSA------------GNVAIKAVS 51 Query: 328 --LIQSREQLDLVKEEIRVSSLFNHPNLLPLL-------DHAIIAVKSTQGDWS----HE 468 +++++ L+ ++ EI + HP+++ LL D ++ GD + Sbjct: 52 RSKLRNKKLLENLEIEIAILKKIKHPHIVGLLECERTGTDFYLMMEYCALGDLTFFIKKR 111 Query: 469 AYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKP 648 L+ L TLF+ + + V+ QQ+ LK + S + H D+KP Sbjct: 112 RSLMDKHPLVRTLFEKYPPPSEHHNGLNRVLVVNYLQQLSSALKFLRSKN--LVHRDIKP 169 Query: 649 GNVLVT------------RQKG-----QAPLATLMDFGSSRPARNQIRSRSEALRLQEWA 777 N+L++ +G P+ + DFG +R N S +E L Sbjct: 170 QNLLLSTPLVDYNDPAEFHARGFVGIYNLPILKIADFGFARFLPN--TSLAETL------ 221 Query: 778 AEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE 915 C +P + APE+ ++ + + D+WS+G LY + G PF+ Sbjct: 222 ---CGSPLYMAPEIL---NYQKYNAKADLWSVGTVLYEMCCGKPPFK 262
>O35099:M3K5_MOUSE Mitogen-activated protein kinase kinase kinase 5 - Mus musculus| (Mouse) Length = 1380 Score = 58.9 bits (141), Expect = 5e-08 Identities = 50/170 (29%), Positives = 78/170 (45%), Gaps = 1/170 (0%) Frame = +1 Query: 577 QQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEA 756 +QI EGLK++H D H D+K NVL+ G + + DFG+S+ I +E Sbjct: 792 KQILEGLKYLH--DNQIVHRDIKGDNVLINTYSG---VLKISDFGTSKRLAG-INPCTET 845 Query: 757 LRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESG 936 + + APE+ D + DIWSLGCT+ + G PF Y LGE Sbjct: 846 FT--------GTLQYMAPEIID-KGPRGYGKAADIWSLGCTIIEMATGKPPF-YELGEPQ 895 Query: 937 GSL-QLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILL 1083 ++ ++ + P++P +A F+ +P P R ND+L+ Sbjct: 896 AAMFKVGMFKVH---PEIPESMSAEA-KAFILKCFEPDPDKRACANDLLI 941
>Q5R4K3:KS6A5_PONPY Ribosomal protein S6 kinase alpha-5 - Pongo pygmaeus (Orangutan)| Length = 802 Score = 58.9 bits (141), Expect = 5e-08 Identities = 54/209 (25%), Positives = 94/209 (44%) Frame = +1 Query: 289 HVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHE 468 H + +A+K +I R + + KE + HPN++ L H + D H Sbjct: 445 HKKSNQAFAVK--IISKRMEANTQKEITALKLCEGHPNIVKL--HEVFH------DQLH- 493 Query: 469 AYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKP 648 +L+ + G LF+ +K+ +S + I +++ + HMH D H D+KP Sbjct: 494 TFLVMELLNGGELFERI----KKKKHFSETEASYIMRKLVSAVSHMH--DVGVVHRDLKP 547 Query: 649 GNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCP 828 N+L T + + ++DFG +RP ++ L+ + + APEL + Sbjct: 548 ENLLFTDENDNLEIK-IIDFGFARPKPPD----NQPLKTPCFTLHYA-----APELLNQN 597 Query: 829 SHADIDERTDIWSLGCTLYAIMYGVSPFE 915 + DE D+WSLG LY ++ G PF+ Sbjct: 598 GY---DESCDLWSLGVILYTMLSGQVPFQ 623 Score = 42.0 bits (97), Expect = 0.006 Identities = 70/290 (24%), Positives = 110/290 (37%), Gaps = 5/290 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGT---YAMKKVLIQSREQLDL 357 F +L+ +G G + V+LV++ +SG T YAMK + + Q Sbjct: 49 FELLKVLGTGAYGKVFLVRK---------------ISGHDTGKLYAMKVLKKATIVQKAK 93 Query: 358 VKEEIRVS-SLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 E R + H P L A ++ + +L+ G LF + S Sbjct: 94 TTEHTRTERQVLEHTRQSPFLVTLHYAFQTET-----KLHLILDYINGGELFTHL----S 144 Query: 535 RKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGS 714 ++E ++ +V +I L+H+H L Y D+K N+L+ L DFG Sbjct: 145 QRERFTEHEVQIYVGEIVLALEHLHKLGIIY--RDIKLENILLDSNGH----VMLTDFGL 198 Query: 715 SRPARNQIRSRSEALRLQEWAAEHCSA-PFRAPELWDCPSHADIDERTDIWSLGCTLYAI 891 S+ R A C + AP++ + D+ D WSLG +Y + Sbjct: 199 SKEFVADETER---------AYSFCGTIEYMAPDIVR-GGDSGHDKAVDWWSLGVLMYEL 248 Query: 892 MYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQ 1041 + G SPF GE Q I LK PPYP + ++Q Sbjct: 249 LTGASPFTVD-GEKNS--QAEISRRILK----SEPPYPQEMSALAKDLIQ 291
>P43637:KGS9_YEAST Probable serine/threonine-protein kinase YGL179C - Saccharomyces| cerevisiae (Baker's yeast) Length = 560 Score = 58.9 bits (141), Expect = 5e-08 Identities = 78/331 (23%), Positives = 125/331 (37%), Gaps = 31/331 (9%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVL----------IQ 336 F +L +G G + V L ++ G G K+L +Q Sbjct: 50 FEILATLGNGQYGKVKLARD----------------LGTGALVAIKILNRFEKRSGYSLQ 93 Query: 337 SREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDN 516 + + V +EI V +H N++ L + S + YL+ G + Sbjct: 94 LKVENPRVNQEIEVMKRCHHENVVELYE-------ILNDPESTKVYLVLEYCSRGPV--- 143 Query: 517 AAVMQSRKEFYSVLDVLRIFQQ-------ICEGLKHMHSLDPPYAHNDVKPGNVLVTRQK 675 +++ E +V + FQQ + GL+++HS H D+KP N+L++ Sbjct: 144 KWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQG--ITHRDIKPSNLLISSNG 201 Query: 676 GQAPLATLMDFG---SSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADID 846 + DFG S+ I+S E L + F APEL Sbjct: 202 ----TVKISDFGVAMSTATGSTNIQSSHEQLLKSRALG---TPAFFAPELCSTEKEYSCS 254 Query: 847 ERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQ-----------LPS 993 DIWSLG T+Y +++G PF SG L +I+N L++P + Sbjct: 255 SAIDIWSLGVTIYCLLFGKLPFN---ANSGLELFDSIINKPLEFPSYEEMLNGATSGITM 311 Query: 994 PPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 Y DA + +LQ P R + DI +H Sbjct: 312 EEYTDA-KDLLKKLLQKDPDKRIKLADIKVH 341
>Q07250:KCCS_MALDO Calcium/calmodulin-dependent serine/threonine-protein kinase - Malus| domestica (Apple) (Malus sylvestris) Length = 415 Score = 58.9 bits (141), Expect = 5e-08 Identities = 64/277 (23%), Positives = 115/277 (41%), Gaps = 9/277 (3%) Frame = +1 Query: 283 PSHVSGDGTYAMKKVLIQSREQLD----LVKEEIRV-----SSLFNHPNLLPLLDHAIIA 435 P H + + Q+R+Q+ L+ EI V ++ HPN++ L D Sbjct: 61 PPHARRNDQNSFAAAAFQTRKQVSISNVLLTNEILVMRKIVENVSPHPNVIDLYD----V 116 Query: 436 VKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSL 615 + G +L+ + G LFD ++E YS + + +QI +GL +H Sbjct: 117 YEDENG-----VHLVLELCSGGELFDRIV----KQERYSEVGAAAVVRQIAQGLAALHRS 167 Query: 616 DPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSA 795 + H D+KP N L +PL +MDFG S + ++ + S Sbjct: 168 N--IVHRDLKPENCLFLDNTVDSPLK-IMDFGLS-----SVEEFTDPV-----VGLFGSI 214 Query: 796 PFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLK 975 + +PE S + ++D+W+LG LY ++ G PF + +S Q IM + Sbjct: 215 DYVSPEAL---SQGQVTSKSDMWALGVILYILLSGYPPF---IAQSNRQKQQMIMAGEFS 268 Query: 976 WPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 + + + + ++ +L+ P RP ++L H Sbjct: 269 FYEKTWKGFLCQPKQLISSLLKVDPDKRPSAQELLDH 305
>O70150:KCC1B_RAT Calcium/calmodulin-dependent protein kinase type 1B - Rattus| norvegicus (Rat) Length = 343 Score = 58.9 bits (141), Expect = 5e-08 Identities = 72/302 (23%), Positives = 118/302 (39%), Gaps = 1/302 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 + + ++G G F+ V L +E ++ A P KK L R + LV+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIP-----------KKAL---RGKEALVEN 60 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 EI V +HPN I+A++ SH YL + G LFD S Sbjct: 61 EIAVLRRISHPN--------IVALEDVHESPSH-LYLAMELVTGGELFDRIMERGS---- 107 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 Y+ D + Q+ + ++HSL H D+KP N+L + + + DFG S+ Sbjct: 108 YTEKDASHLVGQVLGAVSYLHSLG--IVHRDLKPENLLYATPFEDSKIM-VSDFGLSK-- 162 Query: 727 RNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 ++ C P + APEL + + + D+W+LG Y ++ G Sbjct: 163 ----------IQAGNMLGTACGTPGYVAPELLEQKPYG---KAVDVWALGVISYILLCGY 209 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILL 1083 PF ES L I+ A ++ ++ F+ +L+ P R L Sbjct: 210 PPF---YDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQ 266 Query: 1084 HV 1089 H+ Sbjct: 267 HL 268
>Q9QYK9:KCC1B_MOUSE Calcium/calmodulin-dependent protein kinase type 1B - Mus musculus| (Mouse) Length = 343 Score = 58.9 bits (141), Expect = 5e-08 Identities = 72/302 (23%), Positives = 118/302 (39%), Gaps = 1/302 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 + + ++G G F+ V L +E ++ A P KK L R + LV+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIP-----------KKAL---RGKEALVEN 60 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 EI V +HPN I+A++ SH YL + G LFD S Sbjct: 61 EIAVLRRISHPN--------IVALEDVHESPSH-LYLAMELVTGGELFDRIMERGS---- 107 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 Y+ D + Q+ + ++HSL H D+KP N+L + + + DFG S+ Sbjct: 108 YTEKDASHLVGQVLGAVSYLHSLG--IVHRDLKPENLLYATPFEDSKIM-VSDFGLSK-- 162 Query: 727 RNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 ++ C P + APEL + + + D+W+LG Y ++ G Sbjct: 163 ----------IQAGNMLGTACGTPGYVAPELLEQKPYG---KAVDVWALGVISYILLCGY 209 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILL 1083 PF ES L I+ A ++ ++ F+ +L+ P R L Sbjct: 210 PPF---YDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQ 266 Query: 1084 HV 1089 H+ Sbjct: 267 HL 268
>Q6P2M8:KCC1B_HUMAN Calcium/calmodulin-dependent protein kinase type 1B - Homo sapiens| (Human) Length = 343 Score = 58.9 bits (141), Expect = 5e-08 Identities = 72/302 (23%), Positives = 118/302 (39%), Gaps = 1/302 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 + + ++G G F+ V L +E ++ A P KK L R + LV+ Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIP-----------KKAL---RGKEALVEN 60 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 EI V +HPN I+A++ SH YL + G LFD S Sbjct: 61 EIAVLRRISHPN--------IVALEDVHESPSH-LYLAMELVTGGELFDRIMERGS---- 107 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 Y+ D + Q+ + ++HSL H D+KP N+L + + + DFG S+ Sbjct: 108 YTEKDASHLVGQVLGAVSYLHSLG--IVHRDLKPENLLYATPFEDSKIM-VSDFGLSK-- 162 Query: 727 RNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 ++ C P + APEL + + + D+W+LG Y ++ G Sbjct: 163 ----------IQAGNMLGTACGTPGYVAPELLEQKPYG---KAVDVWALGVISYILLCGY 209 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILL 1083 PF ES L I+ A ++ ++ F+ +L+ P R L Sbjct: 210 PPF---YDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALR 266 Query: 1084 HV 1089 H+ Sbjct: 267 HL 268
>Q6RET7:CCAMK_MEDTR Calcium and calcium/calmodulin-dependent serine/threonine-protein| kinase DMI-3 - Medicago truncatula (Barrel medic) Length = 523 Score = 58.9 bits (141), Expect = 5e-08 Identities = 57/235 (24%), Positives = 96/235 (40%) Frame = +1 Query: 376 VSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSV 555 V ++ HPN++ L D + T G +L+ + G LFD YS Sbjct: 99 VENVSPHPNVIDLYD----VYEDTNG-----VHLVLELCSGGELFDRIVAQDK----YSE 145 Query: 556 LDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQ 735 + + QI GL+ +H + H D+KP N L + +PL +MDFG S Sbjct: 146 TEAATVVHQIASGLEAVHRAN--IVHRDLKPENCLFLDVRKDSPLK-IMDFGLS-----S 197 Query: 736 IRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE 915 + ++ + S + +PE S I ++D+WSLG LY ++ G PF Sbjct: 198 VEEFTDPV-----VGLFGSIDYVSPEAL---SQGKITTKSDMWSLGVILYILLSGYPPF- 248 Query: 916 YALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 + ++ Q IMN + + ++ +L P+ RP ++L Sbjct: 249 --IAQNNRQKQQMIMNGNFSFYEKTWKGISQPAKNLISSLLTVDPSKRPSALELL 301
>Q6C842:BUR1_YARLI Serine/threonine-protein kinase BUR1 - Yarrowia lipolytica (Candida| lipolytica) Length = 706 Score = 58.9 bits (141), Expect = 5e-08 Identities = 63/240 (26%), Positives = 108/240 (45%), Gaps = 10/240 (4%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK- 363 ++ L +IGEG F V+ ++ RH A+KK+L+ S ++ V Sbjct: 38 YKPLGKIGEGTFGEVFRAEQ------ITTKRH---------VALKKILLHSEKEGFPVTA 82 Query: 364 -EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHE----AYLLFPVHLDGTLFDNAAVM 528 EIR+ L H N++PL+D A+ +GD S + Y++ P ++D D A ++ Sbjct: 83 LREIRILKLLRHENVIPLVDLAV-----ERGDQSKKERGCVYMVTP-YMD---HDLAGLL 133 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 ++ S + Q+ EG+ ++H+ + H D+K N+LV Q + L DF Sbjct: 134 GNQSVQLSPAHIKCYMLQLLEGIGYLHA--KKFLHRDIKAANILVNDQ----GILKLADF 187 Query: 709 GSSR----PARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGC 876 G +R PA N S++ + + A + +R PEL D+W +GC Sbjct: 188 GLARGYDGPAPN---SQTAGVNTENLTAMVVTRWYRPPEL--ILGDRKYTTAIDMWGIGC 242
>O70405:ULK1_MOUSE Serine/threonine-protein kinase ULK1 - Mus musculus (Mouse)| Length = 1051 Score = 58.5 bits (140), Expect = 6e-08 Identities = 66/260 (25%), Positives = 113/260 (43%), Gaps = 7/260 (2%) Frame = +1 Query: 157 GGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ 336 GG + + F IG G FA V+ + R++H V+ KK L + Sbjct: 6 GGVETVGKFEFSRKDLIGHGAFAVVFKGRH--------REKHDLEVAVK--CINKKNLAK 55 Query: 337 SREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDN 516 S+ L+ +EI++ H N++ L D +A + YL+ G L D Sbjct: 56 SQT---LLGKEIKILKELKHENIVALYDFQEMA---------NSVYLVMEYCNGGDLADY 103 Query: 517 AAVMQSRKEFYSVLDVLRIF-QQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLA 693 M++ E D +R+F QQI ++ +HS H D+KP N+L++ G+ Sbjct: 104 LHTMRTLSE-----DTVRLFLQQIAGAMRLLHSKG--IIHRDLKPQNILLSNPGGRRANP 156 Query: 694 T-----LMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERT 855 + + DFG +R ++ + AA C +P + APE+ + D + Sbjct: 157 SNIRVKIADFGFARYLQSNMM-----------AATLCGSPMYMAPEVIMSQHY---DGKA 202 Query: 856 DIWSLGCTLYAIMYGVSPFE 915 D+WS+G +Y + G +PF+ Sbjct: 203 DLWSIGTIVYQCLTGKAPFQ 222
>Q9JLS3:TAOK2_RAT Serine/threonine-protein kinase TAO2 - Rattus norvegicus (Rat)| Length = 1235 Score = 58.5 bits (140), Expect = 6e-08 Identities = 75/307 (24%), Positives = 120/307 (39%), Gaps = 4/307 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E+ F LR+IG G F VY ARD S V A+KK+ QS E+ Sbjct: 25 EKLFSDLREIGHGSFGAVYF----------ARDVRNSEV-----VAIKKMSYSGKQSNEK 69 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E+R HPN + + H A+L+ ++ L + ++ Sbjct: 70 WQDIIKEVRFLQKLRHPNTIQYRGCYL---------REHTAWLV----MEYCLGSASDLL 116 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + K+ +++ + +GL ++HS + H DVK GN+L++ + L L DF Sbjct: 117 EVHKKPLQEVEIAAVTHGALQGLAYLHSHN--MIHRDVKAGNILLS----EPGLVKLGDF 170 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLY 885 GS+ + A P+ APE+ D + D+WSLG T Sbjct: 171 GSA--------------SIMAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCI 216 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + P + ++ AQ + P L S + + FV LQ P RP Sbjct: 217 ELAERKPPL-----FNMNAMSALYHIAQNESPALQSGHWSEYFRNFVDSCLQKIPQDRPT 271 Query: 1066 INDILLH 1086 +L H Sbjct: 272 SEVLLKH 278
>Q6ZQ29:TAOK2_MOUSE Serine/threonine-protein kinase TAO2 - Mus musculus (Mouse)| Length = 1055 Score = 58.5 bits (140), Expect = 6e-08 Identities = 75/307 (24%), Positives = 120/307 (39%), Gaps = 4/307 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E+ F LR+IG G F VY ARD S V A+KK+ QS E+ Sbjct: 25 EKLFSDLREIGHGSFGAVYF----------ARDVRNSEV-----VAIKKMSYSGKQSNEK 69 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E+R HPN + + H A+L+ ++ L + ++ Sbjct: 70 WQDIIKEVRFLQKLRHPNTIQYRGCYL---------REHTAWLV----MEYCLGSASDLL 116 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + K+ +++ + +GL ++HS + H DVK GN+L++ + L L DF Sbjct: 117 EVHKKPLQEVEIAAVTHGALQGLAYLHSHN--MIHRDVKAGNILLS----EPGLVKLGDF 170 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLY 885 GS+ + A P+ APE+ D + D+WSLG T Sbjct: 171 GSA--------------SIMAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCI 216 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + P + ++ AQ + P L S + + FV LQ P RP Sbjct: 217 ELAERKPPL-----FNMNAMSALYHIAQNESPALQSGHWSEYFRNFVDSCLQKIPQDRPT 271 Query: 1066 INDILLH 1086 +L H Sbjct: 272 SEVLLKH 278
>Q9H2G2:SLK_HUMAN STE20-like serine/threonine-protein kinase - Homo sapiens (Human)| Length = 1235 Score = 58.5 bits (140), Expect = 6e-08 Identities = 59/234 (25%), Positives = 97/234 (41%), Gaps = 2/234 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 + ++ ++G+G F VY + + S AA K + +S E+L+ Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAA---------------KVIDTKSEEELEDYMV 78 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 EI + + +HPN++ LLD + + ++L G + AVM + Sbjct: 79 EIDILASCDHPNIVKLLDAFY---------YENNLWILIEFCAGGAV---DAVMLELERP 126 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 + + + +Q + L ++H D H D+K GN+L T G LA DFG S Sbjct: 127 LTESQIQVVCKQTLDALNYLH--DNKIIHRDLKAGNILFTLD-GDIKLA---DFGVSAKN 180 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHAD--IDERTDIWSLGCTL 882 I+ R + W APE+ C + D D + D+WSLG TL Sbjct: 181 TRTIQRRDSFIGTPYW---------MAPEVVMCETSKDRPYDYKADVWSLGITL 225
>Q9XBQ0:PKN3_MYXXA Serine/threonine-protein kinase pkn3 - Myxococcus xanthus| Length = 547 Score = 58.5 bits (140), Expect = 6e-08 Identities = 67/306 (21%), Positives = 120/306 (39%), Gaps = 13/306 (4%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 ++RV IGEGG V+ ++ ++ L+ + + Sbjct: 17 KYRVEALIGEGGMGKVFRARQLSLDKVVVLK------------VLRHTLLSDERTVARFQ 64 Query: 364 EEIRVSSLFNHPNLLPLLDHA-------IIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAA 522 E + +S NHPN + +LD IA++ G H+ Sbjct: 65 REAKAASRLNHPNSISVLDFGQAEDGALFIAMEYVAGQDLHQ------------------ 106 Query: 523 VMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLM 702 + SR+ + V+RI Q+ L H H D+KP N++V ++ + ++ Sbjct: 107 -ILSREWPLNEGRVVRIVSQVLSALSDAHGAG--VIHRDLKPENIMVEPRRNEPDFVKVL 163 Query: 703 DFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCT 879 DFG ++ I ++ A C P + +PE + +D R+D++++G Sbjct: 164 DFGIAK-----ITDSTDDGPALTRAGFVCGTPEYMSPEQ---ARGSQLDHRSDLYAVGVI 215 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPD-----ALHKFVTWMLQP 1044 LY +M G+ PF ES ++ A + + P P+ PD A+ + + L Sbjct: 216 LYQLMTGLLPF-----ESDSAVGFATKHL-TEEPPPPTRRRPDARISPAMERLILRALSK 269 Query: 1045 QPAMRP 1062 PA RP Sbjct: 270 NPADRP 275
>Q90XC2:NEK8_DANRE Serine/threonine-protein kinase Nek8 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 697 Score = 58.5 bits (140), Expect = 6e-08 Identities = 74/312 (23%), Positives = 135/312 (43%), Gaps = 11/312 (3%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ--SREQLDL 357 ++ + +G G F V+L + S+ +K++ ++ +R++ Sbjct: 3 KYEKTKVVGRGAFGIVHLCRRRTDSA---------------LVILKEIPVEQMTRDERLA 47 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAI------IAVKSTQGDWSHEAYLLFPVHLDGTLFDNA 519 + E +V L +HPN++ ++ + IA++ G GTL D Sbjct: 48 AQNECQVLKLLSHPNIIEYYENFLEDKALMIAMEYAPG---------------GTLADYI 92 Query: 520 AVMQSRKEFYSVLD---VLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPL 690 +K S+LD +L F QI L H+H+ H D+K N+L+ + + + Sbjct: 93 -----QKRCNSLLDEDTILHSFVQILLALYHVHN--KLILHRDLKTQNILLDKHQ---MI 142 Query: 691 ATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSL 870 + DFG S+ + S+S+A + C + +PEL + + ++++DIW+L Sbjct: 143 VKIGDFGISKI----LVSKSKAYTV---VGTPC---YISPELCEGKPY---NQKSDIWAL 189 Query: 871 GCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQP 1050 GC LY + FE A + +L L IM+ S Y L + + ML P Sbjct: 190 GCVLYELASLKRAFEAA---NLPALVLKIMSGTF---APISDRYSPELRQLILNMLNLDP 243 Query: 1051 AMRPHINDILLH 1086 + RP +N+I+ H Sbjct: 244 SKRPQLNEIMAH 255
>P51139:MSK3_MEDSA Glycogen synthase kinase-3 homolog MsK-3 - Medicago sativa (Alfalfa)| Length = 411 Score = 58.5 bits (140), Expect = 6e-08 Identities = 79/322 (24%), Positives = 126/322 (39%), Gaps = 26/322 (8%) Frame = +1 Query: 199 RQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRV 378 R +G G F V+ K + T A+KKVL R + E++ Sbjct: 78 RVVGHGSFGVVFQAKCLETGE---------------TVAIKKVLQDKRYK----NRELQT 118 Query: 379 SSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYL-LFPVHLDGTLFDNAAVMQSRKEFYSV 555 L +HPN++ L H + +T+ D E YL L ++ T+ + + Sbjct: 119 MRLLDHPNVVSL-KHCFFS--TTEKD---ELYLNLVLEYVPETVSRVIRHYNKMNQRMPM 172 Query: 556 LDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQ 735 + V QIC L ++H+ H D+KP N+LV Q + DFGS++ Sbjct: 173 IYVKLYSYQICRALAYIHN-SIGVCHRDIKPQNLLVNPHTHQLKIC---DFGSAKVL--- 225 Query: 736 IRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE 915 ++ + + CS +RAPEL + DIWS GC L ++ G F Sbjct: 226 -------VKGEPNISYICSRYYRAPEL--IFGATEYTTAIDIWSAGCVLGELLLGQPLFP 276 Query: 916 YALGESGGSLQLAIMN-----------------AQLKWPQLPSPPYPDALHK-------- 1020 GESG + I+ + K+PQ+ + P+ HK Sbjct: 277 ---GESGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHPWHKIFHKRMPPEAVD 333 Query: 1021 FVTWMLQPQPAMRPHINDILLH 1086 V+ +LQ P +R + L+H Sbjct: 334 LVSRLLQYSPNLRSTALEALVH 355
>Q8VHF0:MARK3_RAT MAP/microtubule affinity-regulating kinase 3 - Rattus norvegicus| (Rat) Length = 797 Score = 58.5 bits (140), Expect = 6e-08 Identities = 68/282 (24%), Positives = 116/282 (41%), Gaps = 2/282 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK- 363 +R+L+ IG+G FA V L + H+ A+K + L K Sbjct: 56 YRLLKTIGKGNFAKVKLAR---------------HILTGREVAIKIIDKTQLNPTSLQKL 100 Query: 364 -EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRK 540 E+R+ + NHPN++ L + +I + T YL+ G +FD K Sbjct: 101 FREVRIMKILNHPNIVKLFE--VIETEKT-------LYLIMEYASGGEVFDYLVAHGRMK 151 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 E + F+QI +++ H H D+K N+L+ + DFG S Sbjct: 152 E----KEARAKFRQIVSAVQYCHQ--KRIVHRDLKAENLLLDADMN----IKITDFGFS- 200 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 N+ S +L + S P+ APEL+ + + D+WSLG LY ++ G Sbjct: 201 ---NEFTVGS---KLDTFCG---SPPYAAPELFQGKKYDGPE--VDVWSLGVILYTLVSG 249 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFV 1026 PF+ G++ L+ ++ + + P S + L +F+ Sbjct: 250 SLPFD---GQNLKELRERVLRGKYRIPFYMSTDCENLLKRFL 288
>Q03141:MARK3_MOUSE MAP/microtubule affinity-regulating kinase 3 - Mus musculus (Mouse)| Length = 753 Score = 58.5 bits (140), Expect = 6e-08 Identities = 68/282 (24%), Positives = 116/282 (41%), Gaps = 2/282 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK- 363 +R+L+ IG+G FA V L + H+ A+K + L K Sbjct: 56 YRLLKTIGKGNFAKVKLAR---------------HILTGREVAIKIIDKTQLNPTSLQKL 100 Query: 364 -EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRK 540 E+R+ + NHPN++ L + +I + T YL+ G +FD K Sbjct: 101 FREVRIMKILNHPNIVKLFE--VIETEKT-------LYLIMEYASGGEVFDYLVAHGRMK 151 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 E + F+QI +++ H H D+K N+L+ + DFG S Sbjct: 152 E----KEARAKFRQIVSAVQYCHQ--KRIVHRDLKAENLLLDADMN----IKIADFGFS- 200 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 N+ S +L + S P+ APEL+ + + D+WSLG LY ++ G Sbjct: 201 ---NEFTVGS---KLDTFCG---SPPYAAPELFQGKKYDGPE--VDVWSLGVILYTLVSG 249 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFV 1026 PF+ G++ L+ ++ + + P S + L +F+ Sbjct: 250 SLPFD---GQNLKELRERVLRGKYRIPFYMSTDCENLLKRFL 288
>Q61161:M4K2_MOUSE Mitogen-activated protein kinase kinase kinase kinase 2 - Mus| musculus (Mouse) Length = 821 Score = 58.5 bits (140), Expect = 6e-08 Identities = 72/313 (23%), Positives = 117/313 (37%), Gaps = 12/313 (3%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 RF +L+++G G + VY ARD S ++ A+K V + + + ++ Sbjct: 15 RFELLQRVGAGTYGDVY----------KARDTVTSELA-----AVKIVKLDPGDDISSLQ 59 Query: 364 EEIRVSSLFNHPNLLPLL------DHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAV 525 +EI + HPN++ + D I ++ G E Y H G L + Sbjct: 60 QEITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIY-----HATGPLEER--- 111 Query: 526 MQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMD 705 + + ++ +GL H+HS H D+K N+L+T Q G LA D Sbjct: 112 -----------QIAYVCREALKGLHHLHSQGK--IHRDIKGANLLLTLQ-GDVKLA---D 154 Query: 706 FGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCT-- 879 FG S + R + W A PE+ +E D+W+LG T Sbjct: 155 FGVSGELTASVAKRRSFIGTPYWMA---------PEVAAVERKGGYNELCDVWALGITAI 205 Query: 880 ----LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 L ++ + P + S S Q + + +W Q H F+ L Sbjct: 206 ELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQ--------NFHHFLKLALTKN 257 Query: 1048 PAMRPHINDILLH 1086 P RP +L H Sbjct: 258 PKKRPTAERLLQH 270
>Q99683:M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 - Homo sapiens| (Human) Length = 1374 Score = 58.5 bits (140), Expect = 6e-08 Identities = 50/170 (29%), Positives = 78/170 (45%), Gaps = 1/170 (0%) Frame = +1 Query: 577 QQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEA 756 +QI EGLK++H D H D+K NVL+ G + + DFG+S+ I +E Sbjct: 785 KQILEGLKYLH--DNQIVHRDIKGDNVLINTYSG---VLKISDFGTSKRLAG-INPCTET 838 Query: 757 LRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESG 936 + + APE+ D + DIWSLGCT+ + G PF Y LGE Sbjct: 839 FT--------GTLQYMAPEIID-KGPRGYGKAADIWSLGCTIIEMATGKPPF-YELGEPQ 888 Query: 937 GSL-QLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILL 1083 ++ ++ + P++P +A F+ +P P R ND+L+ Sbjct: 889 AAMFKVGMFKVH---PEIPESMSAEA-KAFILKCFEPDPDKRACANDLLV 934
>Q9DG02:KCC2D_XENLA Calcium/calmodulin-dependent protein kinase type II delta chain -| Xenopus laevis (African clawed frog) Length = 475 Score = 58.5 bits (140), Expect = 6e-08 Identities = 64/257 (24%), Positives = 102/257 (39%), Gaps = 1/257 (0%) Frame = +1 Query: 319 KKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 KK+ + ++L+ E ++ L HPN++ L D S + H YL+F + Sbjct: 47 KKLSARDHQKLE---REAKICRLLKHPNIVRLHD-------SISEEGFH--YLVFDLVTG 94 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLV-TRQK 675 G LF++ +E+YS D QQI E + H H H D+KP N+L+ ++ K Sbjct: 95 GELFEDIVA----REYYSEADASHCIQQILESVNHCHL--NGIVHRDLKPENLLLASKLK 148 Query: 676 GQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERT 855 G A L DFG + + Q W + + +PE+ + + Sbjct: 149 GAA--VKLADFGLAIEVQGD---------QQAWFGFAGTPGYLSPEVLRKDPYG---KPV 194 Query: 856 DIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWM 1035 D+W+ G LY ++ G PF E L I +P + M Sbjct: 195 DMWACGVILYILLVGYPPF---WDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKM 251 Query: 1036 LQPQPAMRPHINDILLH 1086 L PA R + + L H Sbjct: 252 LTINPAKRINATEALRH 268
>P05986:KAPC_YEAST cAMP-dependent protein kinase type 3 - Saccharomyces cerevisiae| (Baker's yeast) Length = 398 Score = 58.5 bits (140), Expect = 6e-08 Identities = 68/284 (23%), Positives = 124/284 (43%), Gaps = 3/284 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKE-HDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 F++LR +G G F V+L++ H+ A + +KK I +Q++ Sbjct: 88 FQILRTLGTGSFGRVHLIRSNHNGRFYALK-------------TLKKHTIVKLKQVEHTN 134 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 +E R+ S+ +HP II + T D S + +++ G LF ++++ + Sbjct: 135 DERRMLSIVSHP--------FIIRMWGTFQD-SQQVFMVMDYIEGGELF---SLLRKSQR 182 Query: 544 FYSVLDVLRIFQ-QICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 F + V + + ++C L+++HS D Y D+KP N+L+ + + DFG ++ Sbjct: 183 FPN--PVAKFYAAEVCLALEYLHSKDIIY--RDLKPENILLDKNGH----IKITDFGFAK 234 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 + + C P + APE+ S ++ D WS G +Y ++ Sbjct: 235 -------------YVPDVTYTLCGTPDYIAPEV---VSTKPYNKSVDWWSFGVLIYEMLA 278 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVT 1029 G +PF + I+NA+LK+P P D L K +T Sbjct: 279 GYTPF---YNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLIT 319
>Q9UL54:TAOK2_HUMAN Serine/threonine-protein kinase TAO2 - Homo sapiens (Human)| Length = 1235 Score = 58.2 bits (139), Expect = 8e-08 Identities = 75/307 (24%), Positives = 120/307 (39%), Gaps = 4/307 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E+ F LR+IG G F VY ARD S V A+KK+ QS E+ Sbjct: 25 EKLFSDLREIGHGSFGAVYF----------ARDVRNSEV-----VAIKKMSYSGKQSNEK 69 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E+R HPN + + H A+L+ ++ L + ++ Sbjct: 70 WQDIIKEVRFLQKLRHPNTIQYRGCYL---------REHTAWLV----MEYCLGSASDLL 116 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + K+ +++ + +GL ++HS + H DVK GN+L++ + L L DF Sbjct: 117 EVHKKPLQEVEIAAVTHGALQGLAYLHSHN--MIHRDVKAGNILLS----EPGLVKLGDF 170 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLY 885 GS+ + A P+ APE+ D + D+WSLG T Sbjct: 171 GSA--------------SIMAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCI 216 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + P + ++ AQ + P L S + + FV LQ P RP Sbjct: 217 ELAERKPPL-----FNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDSCLQKIPQDRPT 271 Query: 1066 INDILLH 1086 +L H Sbjct: 272 SEVLLKH 278
>O55092:SLK_CAVPO STE20-like serine/threonine-protein kinase - Cavia porcellus| (Guinea pig) Length = 1231 Score = 58.2 bits (139), Expect = 8e-08 Identities = 60/237 (25%), Positives = 97/237 (40%), Gaps = 2/237 (0%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDL 357 E + + ++G+G F VY + + + AA K + +S E+L+ Sbjct: 31 EEFWETIGELGDGAFGKVYKAQNKETNVLAAA---------------KVIDTKSEEELED 75 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 EI + + +HPN++ LLD + + ++L G + AVM Sbjct: 76 YMVEIDILASCDHPNIVKLLDAFY---------YENNLWILIEFCAGGAV---DAVMLEL 123 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + + + + +Q E L ++H D H D+K GN+L T G LA DFG S Sbjct: 124 ERPLTESQIQVVCKQTLEALNYLH--DNKIIHRDLKAGNILFTLD-GDIKLA---DFGVS 177 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHAD--IDERTDIWSLGCTL 882 I+ R + W APE+ C + D D + D+WSLG TL Sbjct: 178 AKNTRTIQRRDSFIGTPYW---------MAPEVVMCETSKDRPYDYKADVWSLGITL 225
>P65732:PKNJ_MYCTU Probable serine/threonine-protein kinase pknJ - Mycobacterium| tuberculosis Length = 589 Score = 58.2 bits (139), Expect = 8e-08 Identities = 62/267 (23%), Positives = 105/267 (39%), Gaps = 2/267 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 +R+ R +G GG VYL + D A + +S D + + V Sbjct: 14 YRIERMLGAGGMGTVYLARNPDLPRSEALKVLAAELSRDLDFRARFV------------R 61 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD--NAAVMQSRK 540 E V++ +HPN I+AV +G + ++ G D AA M + + Sbjct: 62 EADVAAGLDHPN--------IVAVHQ-RGQFEGRLWIAMQFVDGGNAEDALRAATMTTAR 112 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 Y + ++ + L + H H D+KP N L++R G L DFG +R Sbjct: 113 AVY-------VIGEVAKALDYAHQQG--VIHRDIKPANFLLSRAAGGDERVLLSDFGIAR 163 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 + L + + + APE+ + D R D++SLGC L+ ++ G Sbjct: 164 ALGDT--------GLTSTGSVLATLAYAAPEVL---AGQGFDGRADLYSLGCALFRLLTG 212 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWP 981 +PF +G +A++ L P Sbjct: 213 EAPF-----AAGAGAAVAVVAGHLHQP 234
>P65733:PKNJ_MYCBO Probable serine/threonine-protein kinase pknJ - Mycobacterium bovis| Length = 589 Score = 58.2 bits (139), Expect = 8e-08 Identities = 62/267 (23%), Positives = 105/267 (39%), Gaps = 2/267 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 +R+ R +G GG VYL + D A + +S D + + V Sbjct: 14 YRIERMLGAGGMGTVYLARNPDLPRSEALKVLAAELSRDLDFRARFV------------R 61 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD--NAAVMQSRK 540 E V++ +HPN I+AV +G + ++ G D AA M + + Sbjct: 62 EADVAAGLDHPN--------IVAVHQ-RGQFEGRLWIAMQFVDGGNAEDALRAATMTTAR 112 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 Y + ++ + L + H H D+KP N L++R G L DFG +R Sbjct: 113 AVY-------VIGEVAKALDYAHQQG--VIHRDIKPANFLLSRAAGGDERVLLSDFGIAR 163 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 + L + + + APE+ + D R D++SLGC L+ ++ G Sbjct: 164 ALGDT--------GLTSTGSVLATLAYAAPEVL---AGQGFDGRADLYSLGCALFRLLTG 212 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWP 981 +PF +G +A++ L P Sbjct: 213 EAPF-----AAGAGAAVAVVAGHLHQP 234
>Q12851:M4K2_HUMAN Mitogen-activated protein kinase kinase kinase kinase 2 - Homo| sapiens (Human) Length = 819 Score = 58.2 bits (139), Expect = 8e-08 Identities = 73/313 (23%), Positives = 115/313 (36%), Gaps = 12/313 (3%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 RF +L+++G G + VY ARD S ++ A+K V + + + ++ Sbjct: 14 RFELLQRVGAGTYGDVY----------KARDTVTSELA-----AVKIVKLDPGDDISSLQ 58 Query: 364 EEIRVSSLFNHPNLLPLL------DHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAV 525 +EI + HPN++ + D I ++ G E Y H G L + Sbjct: 59 QEITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIY-----HATGPLEERQIA 113 Query: 526 MQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMD 705 R+ +GL H+HS H D+K N+L+T Q G LA D Sbjct: 114 YVCRERL--------------KGLHHLHSQGK--IHRDIKGANLLLTLQ-GDVKLA---D 153 Query: 706 FGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCT-- 879 FG S + R + W A PE+ +E D+W+LG T Sbjct: 154 FGVSGELTASVAKRRSFIGTPYWMA---------PEVAAVERKGGYNELCDVWALGITAI 204 Query: 880 ----LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQ 1047 L ++ + P + S S Q + + +W Q H F+ L Sbjct: 205 ELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQ--------NFHHFLKLALTKN 256 Query: 1048 PAMRPHINDILLH 1086 P RP +L H Sbjct: 257 PKKRPTAEKLLQH 269
>P0C198:CHK1_USTMA Serine/threonine-protein kinase CHK1 - Ustilago maydis (Smut fungus)| Length = 662 Score = 58.2 bits (139), Expect = 8e-08 Identities = 83/345 (24%), Positives = 134/345 (38%), Gaps = 45/345 (13%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVY-LVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 +R+++ IG GGF+ V+ V S A + S+ K I R ++ Sbjct: 18 YRIVQLIGGGGFSKVFRAVNPSSESHSVAAIKVISYAPNRSN----KYPIDRRA----LQ 69 Query: 364 EEIRVSSLFNHPNLLP---------------------LLDHAIIAVKST----------- 447 +E++V S+ HPN+L L+ A+ K + Sbjct: 70 KEVQVHSILKHPNVLEFLGAVERGVDKNGNAGKEKGILMGEAVATTKESIRARDKERQQM 129 Query: 448 QGDWSHEA------YLLFPVHLDGTLFDNAA----VMQSRKEFYSVLDVLRIFQQICEGL 597 SH+ Y++ + G LFD A V + FY FQQ+ GL Sbjct: 130 LSSPSHDQNYVPGLYMVLELGAGGDLFDKIAPDYGVEEDLAHFY--------FQQLLAGL 181 Query: 598 KHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWA 777 +++HS H D+KP N+L+ + G +A DFG + + + R E Sbjct: 182 EYIHS--QGVTHRDIKPENMLLDAE-GNLKIA---DFGLCSVYKYKGKER-------ELT 228 Query: 778 AEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESG--GSLQL 951 S P+ APE+ P E D+WS G L+A++ G +P++ S + + Sbjct: 229 GACGSLPYIAPEMNGKPYRG---EPVDVWSSGVVLFAMLVGSTPWDEPTSRSPEYSAYRT 285 Query: 952 AIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 + WP++P DAL + M+ P P R I H Sbjct: 286 GKLFEYDPWPRIPQ----DAL-SLLKKMMHPTPEKRITFEGIRRH 325
>O64629:AUR3_ARATH Serine/threonine-protein kinase Aurora-3 - Arabidopsis thaliana| (Mouse-ear cress) Length = 288 Score = 58.2 bits (139), Expect = 8e-08 Identities = 70/310 (22%), Positives = 121/310 (39%), Gaps = 10/310 (3%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDL--- 357 F + R +G+G F VYL +E A+ ++ A+K + + E+ + Sbjct: 22 FEIGRPLGKGKFGRVYLARE-------AKSKY--------IVALKVIFKEQIEKYKIHHQ 66 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPV-------HLDGTLFDN 516 ++ E+ + + HPN+L L W H+ +F + L G L N Sbjct: 67 LRREMEIQTSLRHPNILRLFG------------WFHDNERIFLILEYAHGGELYGVLKQN 114 Query: 517 AAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLAT 696 + + + Y + + L + H H D+KP N+L+ + G+ +A Sbjct: 115 GHLTEQQAATY--------IASLSQALAYCHG--KCVIHRDIKPENLLLDHE-GRLKIA- 162 Query: 697 LMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGC 876 DFG S + N+ ++ L + APE+ + H D D W+LG Sbjct: 163 --DFGWSVQSSNKRKTMCGTL------------DYLAPEMVENRDH---DYAVDNWTLGI 205 Query: 877 TLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAM 1056 Y +YG PFE ES I+ L +P P+ + ++ +L P+ Sbjct: 206 LCYEFLYGNPPFE---AESQKDTFKRILKIDLSFPLTPN--VSEEAKNLISQLLVKDPSK 260 Query: 1057 RPHINDILLH 1086 R I I+ H Sbjct: 261 RLSIEKIMQH 270
>Q8AYG3:TTK_DANRE Dual specificity protein kinase Ttk - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 982 Score = 57.8 bits (138), Expect = 1e-07 Identities = 83/351 (23%), Positives = 140/351 (39%), Gaps = 27/351 (7%) Frame = +1 Query: 145 AATGGGDVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKK 324 +A + I ++F + + IG GG + VY V +H HV YA+K Sbjct: 639 SAFSNESITIKGKQFFIFKMIGRGGSSKVYQVFDHK-----------KHV-----YAVKY 682 Query: 325 VLIQSREQ--LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD 498 V ++ + ++ K EI H N L II + + S+ L+ HLD Sbjct: 683 VNLEEADAQAVESYKNEIE------HLNHLQQYSDQIIKLYDYEITSSYIYMLMECGHLD 736 Query: 499 GTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKG 678 + +++RK LD ++ + E + +H H+D+KP N L+ Sbjct: 737 LNTW-----LRNRKTV-KPLDRKAYWRNMLEAVHTIHKHG--IVHSDLKPANFLIVDGS- 787 Query: 679 QAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPE-LWDCPSH----ADI 843 L+DFG + NQI+ ++ + + PE + D S+ + I Sbjct: 788 ----LKLIDFGIA----NQIQPDVTSIMKDSQVG---TLNYMPPEAIKDTSSNGKPGSKI 836 Query: 844 DERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKF 1023 + D+WSLGC LY + YG +PF+ + + + ++ +P +P D L K Sbjct: 837 SAKGDVWSLGCILYCMTYGKTPFQNITNQISKIHAIIDPSHEIDFPDIPEKDLLDVLKKC 896 Query: 1024 VT-----------------WMLQPQPAMRP---HINDILLHVDKLVEKYSP 1116 + LQPQPA P +D +++LV SP Sbjct: 897 LVRNPRERISIAELLDHPYLQLQPQPAPEPAETSSSDFKRILNELVALQSP 947
>Q2TA06:STK6_BOVIN Serine/threonine-protein kinase 6 - Bos taurus (Bovine)| Length = 402 Score = 57.8 bits (138), Expect = 1e-07 Identities = 64/300 (21%), Positives = 114/300 (38%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F + R +G+G F VYL +E + A + K ++ ++ Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALK------------VLFKAQLEKAGVEHQLRR 180 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 E+ + S HPN+L L + A + YL+ G ++ + E Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATR---------VYLILEYAPLGAVYRELQKLSKFDEQ 231 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 + + ++ L + HS H D+KP N+L+ G A + DFG S A Sbjct: 232 RTATYIT----ELANALSYCHS--KRVIHRDIKPENLLL----GSAGELKIADFGWSVHA 281 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 + R+ + + PE+ + H DE+ D+WSLG Y + G Sbjct: 282 PSSRRTTLCG-----------TLDYLPPEMIEGRMH---DEKVDLWSLGVLCYEFLVGKP 327 Query: 907 PFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 PFE ++ I + +P P+ ++ +L+ P+ RP + ++L H Sbjct: 328 PFE---ADTYQETYRRISRVEFTFPDC----VPEGARDLISRLLKHNPSQRPTLKEVLEH 380
>Q9URY1:PPK16_SCHPO Serine/threonine-protein kinase ppk16 - Schizosaccharomyces pombe| (Fission yeast) Length = 672 Score = 57.8 bits (138), Expect = 1e-07 Identities = 80/305 (26%), Positives = 122/305 (40%), Gaps = 5/305 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 +R+ +GEG F VYL +H+ + +K R+Q ++ Sbjct: 31 YRIESVVGEGSFGKVYLA---------------AHLLTNTKVVLKS---SCRKQAIILAR 72 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 EI HPN+ L + V T+ YL +G L+D A R++ Sbjct: 73 EIHHHRRLLHPNITRLYE-----VVCTED----RIYLAMEYCPNGELYDWVA----REKR 119 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 RI Q+C ++++H H D+K N+ + + A L DFG SR + Sbjct: 120 LDEKTTCRIMWQLCCAIQYLHRQG--CVHRDLKLENIFLDK----AYNVKLGDFGFSRDS 173 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 SR + + +C APEL H I E DIWSLG +YA++ G Sbjct: 174 DC---SRRTFMNTRCGTVAYC-----APEL--VQGHKYIGECVDIWSLGIIMYALLIGRL 223 Query: 907 PFEYALGESGGSL-QLAIMNAQLKWPQLPSPPYPDALHK----FVTWMLQPQPAMRPHIN 1071 PF+ E SL + I+N P YP+ L K + +L +RP I+ Sbjct: 224 PFD----EDDVSLTEQKIIN--------ECPQYPETLSKNSSSLLKSLLCKDYRLRPSID 271 Query: 1072 DILLH 1086 I+ H Sbjct: 272 QIISH 276
>Q20845:PLK3_CAEEL Serine/threonine-protein kinase plk-3 - Caenorhabditis elegans| Length = 615 Score = 57.8 bits (138), Expect = 1e-07 Identities = 67/301 (22%), Positives = 115/301 (38%), Gaps = 8/301 (2%) Frame = +1 Query: 205 IGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRVSS 384 +GEGGFA + ++ D + A P K +L++S + L +E + + Sbjct: 41 LGEGGFAHCFEFRKLDCNDRLAVKVVP-----------KVILLKSTAREKLTRE-VEIHR 88 Query: 385 LFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFD----NAAVMQSRKEFYS 552 +H N++ H + S Y + +L + + + FY+ Sbjct: 89 QLSHRNIVQF--HHFF-------EDSQNVYFTLELCSKNSLMELNKQRGPLTEHEARFYT 139 Query: 553 VLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQK----GQAPLATLMDFGSSR 720 + Q+ EG+KH+H+L H D+K GN+ + G LAT + + Sbjct: 140 I--------QVAEGVKHLHNLQ--IIHRDLKLGNLFLNEHLQVKIGDFGLATFCEKNEKK 189 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 R + + APE+ + HA DIW++GC LY +++G Sbjct: 190 MTRGGTPN------------------YIAPEVLNETGHAF---EVDIWAIGCILYVLLFG 228 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PFE + I N P+ SP ++ + +L P P RP +L Sbjct: 229 SPPFE---SRRVQETYVRIKNNDYVVPENASP----TANRLIRSLLDPVPDRRPTAEAVL 281 Query: 1081 L 1083 L Sbjct: 282 L 282
>Q8G6P9:PKNB_BIFLO Probable serine/threonine-protein kinase pknB - Bifidobacterium| longum Length = 690 Score = 57.8 bits (138), Expect = 1e-07 Identities = 53/243 (21%), Positives = 102/243 (41%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R+++ + IG GG A V++ + A + ++ D + + + Sbjct: 13 RYQLGQLIGRGGMAEVHVALDTRLGRTVAVKIMRADLANDDIFLAR------------FR 60 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E + N+PN++ + D V S GD Y++ TL D V + Sbjct: 61 REAHAVAQMNNPNIVNIYDSGEELVSSESGDAERLPYIVMEYVKGQTLRDIIKVNGA--- 117 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 S D ++ + L + H + H D+KPGN++++ Q + +MDFG +R Sbjct: 118 -LSQRDCEQVMLGVLNALDYSHRMG--IIHRDIKPGNIMISEQG----VVKVMDFGIARA 170 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGV 903 + + +++ + +A + +PE +D R+D++S GC LY ++ G Sbjct: 171 LDDSAATMTQSQGVVG------TAQYLSPEQ---ARGETVDMRSDLYSAGCVLYEMLTGR 221 Query: 904 SPF 912 PF Sbjct: 222 PPF 224
>P51955:NEK2_HUMAN Serine/threonine-protein kinase Nek2 - Homo sapiens (Human)| Length = 445 Score = 57.8 bits (138), Expect = 1e-07 Identities = 65/266 (24%), Positives = 113/266 (42%), Gaps = 5/266 (1%) Frame = +1 Query: 298 GDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYL 477 G T A K++L+ +++L++E HPN++ D I +T Y+ Sbjct: 42 GSMTEAEKQMLVS---EVNLLRE-------LKHPNIVRYYDRIIDRTNTT-------LYI 84 Query: 478 LFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDP---PYAHNDVKP 648 + G L +++ VLR+ Q+ LK H H D+KP Sbjct: 85 VMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKP 144 Query: 649 GNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDC 825 NV + ++ L DFG +R + +A P+ +PE + Sbjct: 145 ANVFLDGKQN----VKLGDFGLARILNHDT----------SFAKTFVGTPYYMSPEQMNR 190 Query: 826 PSHADIDERTDIWSLGCTLYAIMYGVSPF-EYALGESGGSLQLAIMNAQLKWPQLPSPPY 1002 S+ +E++DIWSLGC LY + + PF ++ E G ++ + K+ ++P Y Sbjct: 191 MSY---NEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIR------EGKFRRIPY-RY 240 Query: 1003 PDALHKFVTWMLQPQPAMRPHINDIL 1080 D L++ +T ML + RP + +IL Sbjct: 241 SDELNEIITRMLNLKDYHRPSVEEIL 266
>Q8NG66:NEK11_HUMAN Serine/threonine-protein kinase Nek11 - Homo sapiens (Human)| Length = 645 Score = 57.8 bits (138), Expect = 1e-07 Identities = 72/301 (23%), Positives = 117/301 (38%), Gaps = 1/301 (0%) Frame = +1 Query: 181 RRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLV 360 RR+ + +++G G F VYLV + A G+ +K++ + + V Sbjct: 27 RRYVLQQKLGSGSFGTVYLVSDKKAKR------------GEELKVLKEISVGELNPNETV 74 Query: 361 KEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGT-LFDNAAVMQSR 537 + + LL LDH I VK + + + + +G L D + Sbjct: 75 QANLEAQ-------LLSKLDHPAI-VKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQA 126 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + + ++ F Q+ G+ +MH + H D+K NV + L + DFG S Sbjct: 127 GKIFPENQIIEWFIQLLLGVDYMH--ERRILHRDLKSKNVFLKNN-----LLKIGDFGVS 179 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 R + S L H +P + H D ++DIWSL C LY + Sbjct: 180 R-----LLMGSCDLATTLTGTPHYMSP-------EALKHQGYDTKSDIWSLACILYEMCC 227 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDI 1077 F G + S+ L I+ P LP YP L+ + ML P++RP +I Sbjct: 228 MNHAF---AGSNFLSIVLKIVEGDT--PSLPE-RYPKELNAIMESMLNKNPSLRPSAIEI 281 Query: 1078 L 1080 L Sbjct: 282 L 282
>O08679:MARK2_RAT Serine/threonine-protein kinase MARK2 - Rattus norvegicus (Rat)| Length = 722 Score = 57.8 bits (138), Expect = 1e-07 Identities = 67/280 (23%), Positives = 116/280 (41%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 +R+L+ IG+G FA V L + + A + K + S L + Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVA------------VKIIDKTQLNS-SSLQKLFR 99 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 E+R+ + NHPN++ L + +I + T YL+ G +FD KE Sbjct: 100 EVRIMKVLNHPNIVKLFE--VIETEKT-------LYLVMEYASGGEVFDYLVAHGRMKE- 149 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 + F+QI +++ H H D+K N+L+ + DFG S Sbjct: 150 ---KEARAKFRQIVSAVQYCHQKF--IVHRDLKAENLLLDADMN----IKIADFGFS--- 197 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 N+ + +L + S P+ APEL+ + + D+WSLG LY ++ G Sbjct: 198 -NEFTFGN---KLDTFCG---SPPYAAPELFQGKKYDGPE--VDVWSLGVILYTLVSGSL 248 Query: 907 PFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFV 1026 PF+ G++ L+ ++ + + P S + L KF+ Sbjct: 249 PFD---GQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 285
>Q7KZI7:MARK2_HUMAN Serine/threonine-protein kinase MARK2 - Homo sapiens (Human)| Length = 788 Score = 57.8 bits (138), Expect = 1e-07 Identities = 67/280 (23%), Positives = 116/280 (41%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 +R+L+ IG+G FA V L + + A + K + S L + Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVA------------VKIIDKTQLNS-SSLQKLFR 99 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 E+R+ + NHPN++ L + +I + T YL+ G +FD KE Sbjct: 100 EVRIMKVLNHPNIVKLFE--VIETEKT-------LYLVMEYASGGEVFDYLVAHGRMKE- 149 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 + F+QI +++ H H D+K N+L+ + DFG S Sbjct: 150 ---KEARAKFRQIVSAVQYCHQKF--IVHRDLKAENLLLDADMN----IKIADFGFS--- 197 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 N+ + +L + S P+ APEL+ + + D+WSLG LY ++ G Sbjct: 198 -NEFTFGN---KLDTFCG---SPPYAAPELFQGKKYDGPE--VDVWSLGVILYTLVSGSL 248 Query: 907 PFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFV 1026 PF+ G++ L+ ++ + + P S + L KF+ Sbjct: 249 PFD---GQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 285
>O75582:KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 - Homo sapiens (Human)| Length = 802 Score = 57.8 bits (138), Expect = 1e-07 Identities = 54/212 (25%), Positives = 93/212 (43%), Gaps = 3/212 (1%) Frame = +1 Query: 289 HVSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHE 468 H + +A+K +I R + + KE + HPN++ L H + D H Sbjct: 445 HKKSNQAFAVK--IISKRMEANTQKEITALKLCEGHPNIVKL--HEVFH------DQLH- 493 Query: 469 AYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKP 648 +L+ + G LF+ +K+ +S + I +++ + HMH D H D+KP Sbjct: 494 TFLVMELLNGGELFERI----KKKKHFSETEASYIMRKLVSAVSHMH--DVGVVHRDLKP 547 Query: 649 GNVLVTRQKGQAPLATLMDFGSSR---PARNQIRSRSEALRLQEWAAEHCSAPFRAPELW 819 N+L T + + ++DFG +R P +++ L + APEL Sbjct: 548 ENLLFTDENDNLEIK-IIDFGFARLKPPDNQPLKTPCFTLH------------YAAPELL 594 Query: 820 DCPSHADIDERTDIWSLGCTLYAIMYGVSPFE 915 + + DE D+WSLG LY ++ G PF+ Sbjct: 595 NQNGY---DESCDLWSLGVILYTMLSGQVPFQ 623 Score = 43.1 bits (100), Expect = 0.003 Identities = 69/293 (23%), Positives = 112/293 (38%), Gaps = 8/293 (2%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGT---YAMKKV----LIQSRE 345 F +L+ +G G + V+LV++ +SG T YAMK + ++Q + Sbjct: 49 FELLKVLGTGAYGKVFLVRK---------------ISGHDTGKLYAMKVLKKATIVQKAK 93 Query: 346 QLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAV 525 + + E +V L L +A + +L+ G LF + Sbjct: 94 TTEHTRTERQVLEHIRQSPFLVTLHYAF--------QTETKLHLILDYINGGELFTHL-- 143 Query: 526 MQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMD 705 S++E ++ +V +I L+H+H L Y D+K N+L+ L D Sbjct: 144 --SQRERFTEHEVQIYVGEIVLALEHLHKLGIIY--RDIKLENILLDSNGH----VVLTD 195 Query: 706 FGSSRPARNQIRSRSEALRLQEWAAEHCSA-PFRAPELWDCPSHADIDERTDIWSLGCTL 882 FG S+ R A C + AP++ + D+ D WSLG + Sbjct: 196 FGLSKEFVADETER---------AYSFCGTIEYMAPDIVR-GGDSGHDKAVDWWSLGVLM 245 Query: 883 YAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQ 1041 Y ++ G SPF GE Q I LK PPYP + ++Q Sbjct: 246 YELLTGASPFTVD-GEKNS--QAEISRRILK----SEPPYPQEMSALAKDLIQ 291
>P49673:KAPC_ASCSU cAMP-dependent protein kinase catalytic subunit - Ascaris suum (Pig| roundworm) (Ascaris lumbricoides) Length = 337 Score = 57.8 bits (138), Expect = 1e-07 Identities = 63/252 (25%), Positives = 108/252 (42%), Gaps = 5/252 (1%) Frame = +1 Query: 172 INERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ---SR 342 +N F + IG G F VYLV+ H + + +A+KK+ I+ S Sbjct: 24 LNVDDFDRICTIGTGSFGRVYLVQ---------------HRASEQYFALKKMAIREVVSM 68 Query: 343 EQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWS-HEAYLLFPVHLDGTLFDNA 519 Q + V E R+ S +HP + VK W + Y+LF G LF Sbjct: 69 RQTEHVHSEKRLLSRLSHPFI----------VKMYCASWDKYNLYMLFEYLAGGELF--- 115 Query: 520 AVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATL 699 + +++ + F + + + +C L+++HS + A+ D+KP N+++ ++ + Sbjct: 116 SYLRASRTFSNSMARFYAAEIVC-ALQYLHSKN--IAYRDLKPENLMLNKEGH----LKM 168 Query: 700 MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGC 876 DFG ++ ++ W C P + APE+ H D D WSLG Sbjct: 169 TDFGFAKEVIDRT-----------WTM--CGTPEYLAPEVIGNKGH---DTAVDWWSLGV 212 Query: 877 TLYAIMYGVSPF 912 +Y +M G+ PF Sbjct: 213 LIYEMMIGIPPF 224
>Q9HFW2:CLA4_ASHGO Serine/threonine-protein kinase CLA4 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 793 Score = 57.8 bits (138), Expect = 1e-07 Identities = 67/277 (24%), Positives = 121/277 (43%), Gaps = 8/277 (2%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKE-----HDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQL 351 F+++ + G+G VYL + +D +S ++ ++ GD A+K++++ + + Sbjct: 498 FQMIEKAGQGASGSVYLAQRLKIPPYDENSGVSQHELNDNI-GDKV-AIKQMILSKQPRK 555 Query: 352 DLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGD-WSHEAYLLFPVHLDGTLFDNAAVM 528 +L+ EI V H N++ L+ A T+ D W Y+ D + +N+ Sbjct: 556 ELIVNEILVMKDSQHKNIVNFLE----AYLKTEDDLWVVMEYMEGGSLTD--VIENSIGS 609 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + + + + I ++ C+GLK +H D H D+K NVL+ G+ + DF Sbjct: 610 DASESPMTEPQIAYIVRETCQGLKFLH--DKHIIHRDIKSDNVLLDTH-GRVKIT---DF 663 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYA 888 G ++ R+ + W A PE+ + DE+ D+WSLG Sbjct: 664 GFCAKLTDKRSKRATMVGTPYWMA---------PEV---VKQREYDEKVDVWSLGIMTIE 711 Query: 889 IMYGVSPFEYALGESGGSLQLAIMNA--QLKWPQLPS 993 ++ G P Y E +L L N +LK P+L S Sbjct: 712 MLEGEPP--YLNEEPLKALYLIATNGTPKLKHPELLS 746
>Q6GPL3:AUKBB_XENLA Serine/threonine-protein kinase 12-B - Xenopus laevis (African clawed| frog) Length = 368 Score = 57.8 bits (138), Expect = 1e-07 Identities = 73/304 (24%), Positives = 123/304 (40%), Gaps = 4/304 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLV-- 360 F + R +G+G F VYL +E A KVL +S+ + + V Sbjct: 100 FDIGRPLGKGKFGNVYLAREKQNKFIMAL----------------KVLFKSQLEKEGVEH 143 Query: 361 --KEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 + EI + S HPN+L + ++ + YL+ G L+ +Q Sbjct: 144 QLRREIEIQSHLRHPNILRMYNYFHDRKR---------IYLMLEFAPRGELYKE---LQK 191 Query: 535 RKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGS 714 F +++ + L++ H + H D+KP N+L+ KG+ +A DFG Sbjct: 192 HGRFDEQRSAT-FMEELADALQYCH--ERKVIHRDIKPENLLMG-YKGELKIA---DFGW 244 Query: 715 SRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 S A + +R R+ L + PE+ + +H DE+ D+W G Y + Sbjct: 245 SVHAPS-LRRRTMCGTLD----------YLPPEMIEGKTH---DEKVDLWCAGVLCYEFL 290 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHIND 1074 G+ PF+ S I+N LK+P S D + K +L+ PA R + Sbjct: 291 VGMPPFD---SPSHSETHRRIVNVDLKFPPFLSEGSKDLISK----LLRYHPAQRLPLKG 343 Query: 1075 ILLH 1086 ++ H Sbjct: 344 VMEH 347
>Q6GPK9:TAOK2_XENLA Serine/threonine-protein kinase TAO2 - Xenopus laevis (African clawed| frog) Length = 1025 Score = 57.4 bits (137), Expect = 1e-07 Identities = 70/307 (22%), Positives = 120/307 (39%), Gaps = 4/307 (1%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI---QSREQ 348 E+ F LR+IG G F VY ++ + + A+KK+ QS E+ Sbjct: 25 EKLFADLREIGHGSFGAVYFARD---------------IRNNEVVAIKKMSYSGKQSNEK 69 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 + +E++ HPN + + H A+L+ ++ L + ++ Sbjct: 70 WQDIIKEVKFLQKLRHPNTIEYKGCYL---------REHTAWLV----MEYCLGSASDLL 116 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + K+ +++ I +GL ++H+ + H DVK GN+L+T + L L DF Sbjct: 117 EVHKKPLQEMEIAAITHGALQGLAYLHNHN--MIHRDVKAGNILLT----EPGLVKLGDF 170 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPF-RAPELWDCPSHADIDERTDIWSLGCTLY 885 GS+ + A P+ APE+ D + D+WSLG T Sbjct: 171 GSA--------------SIMAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITSI 216 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + P + ++ AQ + P L S + + FV LQ P RP Sbjct: 217 ELAERKPPL-----FNMNAMSALYHIAQNESPVLQSNHWSEYFRNFVDSCLQKIPQDRPT 271 Query: 1066 INDILLH 1086 + +L H Sbjct: 272 SDMLLKH 278
>Q91819:STK6L_XENLA Serine/threonine-protein kinase Eg2-like - Xenopus laevis (African| clawed frog) Length = 408 Score = 57.4 bits (137), Expect = 1e-07 Identities = 76/304 (25%), Positives = 121/304 (39%), Gaps = 4/304 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F + R +G+G F VYL +E ++ A KVL +S+ + V+ Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILAL----------------KVLFKSQLEKAGVEH 183 Query: 367 EIR----VSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 ++R + S HPN+L L + A + YL+ G LF +Q Sbjct: 184 QLRREVEIQSHLRHPNILRLYGYFHDASR---------VYLILDYAPGGELFRE---LQK 231 Query: 535 RKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGS 714 F L I +Q+ E L + HS H D+KP N+L+ G+ +A DFG Sbjct: 232 CTRFDDQRSALYI-KQLAEALLYCHS--KKVIHRDIKPENLLLG-SNGELKIA---DFGW 284 Query: 715 SRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 S A + R+ + + PE+ + H DE+ D+WSLG Y + Sbjct: 285 SVHAPSSRRTTLCG-----------TLDYLPPEMIEGRMH---DEKVDLWSLGVLCYEFL 330 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHIND 1074 G PFE ++ I + ++P S D + K +L+ P R + Sbjct: 331 VGKPPFE---TDTHQETYRRISKVEFQYPPYVSEEAKDLVSK----LLKHNPNHRLPLKG 383 Query: 1075 ILLH 1086 +L H Sbjct: 384 VLEH 387
>Q63553:SNRK_RAT SNF-related serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 746 Score = 57.4 bits (137), Expect = 1e-07 Identities = 64/249 (25%), Positives = 99/249 (39%), Gaps = 8/249 (3%) Frame = +1 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 +E+R L HPN++ L + D + YL+ + G +FD +M+ + Sbjct: 62 QEVRCMKLVQHPNIVRLYEVI---------DTQTKLYLILELGDGGDMFDY--IMKHEEG 110 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS-- 717 L + F QI + + H L H D+KP NV+ ++G L L DFG S Sbjct: 111 LNEDL-AKKYFAQIVHAISYCHKLH--VVHRDLKPENVVFFEKQG---LVKLTDFGFSNK 164 Query: 718 -RPARNQIRSRSEALRLQEWAAEHCSAPFRAPEL-----WDCPSHADIDERTDIWSLGCT 879 +P + S S + APE+ +D P+ DIWSLG Sbjct: 165 FQPGKKLTTSCG-------------SLAYSAPEILLGDEYDAPA-------VDIWSLGVI 204 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 L+ ++ G PF+ A + IM+ + P P +T MLQ P R Sbjct: 205 LFMLVCGQPPFQEA---NDSETLTMIMDCKYTVP----PRVSAGCRDLITRMLQRDPKRR 257 Query: 1060 PHINDILLH 1086 + +I H Sbjct: 258 ASLEEIESH 266
>Q8VDU5:SNRK_MOUSE SNF-related serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 748 Score = 57.4 bits (137), Expect = 1e-07 Identities = 64/249 (25%), Positives = 99/249 (39%), Gaps = 8/249 (3%) Frame = +1 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 +E+R L HPN++ L + D + YL+ + G +FD +M+ + Sbjct: 62 QEVRCMKLVQHPNIVRLYEVI---------DTQTKLYLILELGDGGDMFDY--IMKHEEG 110 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS-- 717 L + F QI + + H L H D+KP NV+ ++G L L DFG S Sbjct: 111 LNEDL-AKKYFAQIVHAISYCHKLH--VVHRDLKPENVVFFEKQG---LVKLTDFGFSNK 164 Query: 718 -RPARNQIRSRSEALRLQEWAAEHCSAPFRAPEL-----WDCPSHADIDERTDIWSLGCT 879 +P + S S + APE+ +D P+ DIWSLG Sbjct: 165 FQPGKKLTTSCG-------------SLAYSAPEILLGDEYDAPA-------VDIWSLGVI 204 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 L+ ++ G PF+ A + IM+ + P P +T MLQ P R Sbjct: 205 LFMLVCGQPPFQEA---NDSETLTMIMDCKYTVP----PRVSAGCRDLITRMLQRDPKRR 257 Query: 1060 PHINDILLH 1086 + +I H Sbjct: 258 ASLEEIESH 266
>Q9NRH2:SNRK_HUMAN SNF-related serine/threonine-protein kinase - Homo sapiens (Human)| Length = 765 Score = 57.4 bits (137), Expect = 1e-07 Identities = 65/249 (26%), Positives = 100/249 (40%), Gaps = 8/249 (3%) Frame = +1 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 +E+R L HPN++ L + D + YL+ + G +FD +M+ + Sbjct: 62 QEVRCMKLVQHPNIVRLYEVI---------DTQTKLYLILELGDGGDMFDY--IMKHEEG 110 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS-- 717 L + F QI + + H L H D+KP NV+ ++G L L DFG S Sbjct: 111 LNEDL-AKKYFAQIVHAISYCHKLH--VVHRDLKPENVVFFEKQG---LVKLTDFGFSNK 164 Query: 718 -RPARNQIRSRSEALRLQEWAAEHCSAPFRAPEL-----WDCPSHADIDERTDIWSLGCT 879 +P + S S + APE+ +D P+ DIWSLG Sbjct: 165 FQPGKKLTTSCG-------------SLAYSAPEILLGDEYDAPA-------VDIWSLGVI 204 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 L+ ++ G PF+ A + IM+ + P S D +T MLQ P R Sbjct: 205 LFMLVCGQPPFQEA---NDSETLTMIMDCKYTVPSHVSKECKD----LITRMLQRDPKRR 257 Query: 1060 PHINDILLH 1086 + +I H Sbjct: 258 ASLEEIENH 266
>Q11053:PKNH_MYCTU Probable serine/threonine-protein kinase pknH - Mycobacterium| tuberculosis Length = 626 Score = 57.4 bits (137), Expect = 1e-07 Identities = 68/294 (23%), Positives = 116/294 (39%), Gaps = 3/294 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ-SREQL--DL 357 + + R +G GG VY H + T A+K + + S++ + + Sbjct: 16 YHLKRLLGRGGMGEVY---------------EAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 +K E R++ P+++P+ D+ + G E L+ LD L + R Sbjct: 61 MKREARIAGRLQEPHVVPIHDYGEV-----DGQMFLEMRLVEGTDLDSVLKRFGPLTPPR 115 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + I QI L H+ H DVKP N+L+TR A L+DFG Sbjct: 116 --------AVAIITQIASALDAAHA--DGVMHRDVKPQNILITRDD----FAYLVDFG-- 159 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 I S + +L + + + APE + S+ ++ R DI++L C L+ + Sbjct: 160 ------IASATTDEKLTQLGTAVGTWKYMAPERF---SNDEVTYRADIYALACVLHECLT 210 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 G P+ +S G+L + + + P P P A V + +P R Sbjct: 211 GAPPYR---ADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVARGMAKKPEDR 261
>Q7U095:PKNH_MYCBO Probable serine/threonine-protein kinase pknH - Mycobacterium bovis| Length = 596 Score = 57.4 bits (137), Expect = 1e-07 Identities = 68/294 (23%), Positives = 116/294 (39%), Gaps = 3/294 (1%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQ-SREQL--DL 357 + + R +G GG VY H + T A+K + + S++ + + Sbjct: 16 YHLKRLLGRGGMGEVY---------------EAEHTVKEWTVAVKLMTAEFSKDPVFRER 60 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 +K E R++ P+++P+ D+ + G E L+ LD L + R Sbjct: 61 MKREARIAGRLQEPHVVPIHDYGEV-----DGQMFLEMRLVEGTDLDSVLKRFGPLTPPR 115 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + I QI L H+ H DVKP N+L+TR A L+DFG Sbjct: 116 --------AVAIITQIASALDAAHA--DGVMHRDVKPQNILITRDD----FAYLVDFG-- 159 Query: 718 RPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 I S + +L + + + APE + S+ ++ R DI++L C L+ + Sbjct: 160 ------IASATTDEKLTQLGTAVGTWKYMAPERF---SNDEVTYRADIYALACVLHECLT 210 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 G P+ +S G+L + + + P P P A V + +P R Sbjct: 211 GAPPYR---ADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVARGMAKKPEDR 261
>P00518:PHKG1_RABIT Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform| - Oryctolagus cuniculus (Rabbit) Length = 387 Score = 57.4 bits (137), Expect = 1e-07 Identities = 72/306 (23%), Positives = 125/306 (40%), Gaps = 10/306 (3%) Frame = +1 Query: 292 VSGDGTYAMKKVLIQSREQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEA 471 V+G G+++ ++V Q + L + +I + + HPN++ L D + + Sbjct: 53 VTGGGSFSAEEV--QELREATLKEVDI-LRKVSGHPNIIQLKDTY---------ETNTFF 100 Query: 472 YLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPG 651 +L+F + G LFD + K S + +I + + E + +H L+ H D+KP Sbjct: 101 FLVFDLMKKGELFDYL----TEKVTLSEKETRKIMRALLEVICALHKLN--IVHRDLKPE 154 Query: 652 NVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCP 828 N+L+ L DFG S E LR E C P + APE+ +C Sbjct: 155 NILLDDDMN----IKLTDFGFSCQL-----DPGEKLR------EVCGTPSYLAPEIIECS 199 Query: 829 ---SHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPP 999 +H + D+WS G +Y ++ G PF + + IM+ ++ Sbjct: 200 MNDNHPGYGKEVDMWSTGVIMYTLLAGSPPFWH---RKQMLMLRMIMSGNYQFGSPEWDD 256 Query: 1000 YPDALHKFVTWMLQPQPAMRPHINDILLH------VDKLVEKYSP*SQLAYSVLTCFFFI 1161 Y D + V+ L QP R + L H V + V +SP + LT + Sbjct: 257 YSDTVKDLVSRFLVVQPQKRYTAEEALAHPFFQQYVVEEVRHFSPRGKFKVICLTVLASV 316 Query: 1162 RLQREH 1179 R+ ++ Sbjct: 317 RIYYQY 322
>Q5R7G9:NUAK2_PONPY NUAK family SNF1-like kinase 2 - Pongo pygmaeus (Orangutan)| Length = 628 Score = 57.4 bits (137), Expect = 1e-07 Identities = 65/302 (21%), Positives = 116/302 (38%), Gaps = 1/302 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R+ L +G+G + V +E A + +++K I+ + L ++ Sbjct: 52 RYEFLETLGKGTYGKVKKARESSGRLVAIK-------------SIRKDKIKDEQDLMHIR 98 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 EI + S NHP+++ + H + + S + ++ G L+D + Q E Sbjct: 99 REIEIMSSLNHPHIIAI--HEVF-------ENSSKIVIVMEYASRGDLYDYISERQQLSE 149 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 + F+QI + + H H D+K N+L+ G +A DFG S Sbjct: 150 ----REARHFFRQIVSAVHYCHQ--NRVVHRDLKLENILLDAN-GNIKIA---DFGLSN- 198 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 ++ C +P + +PE+ + + + D WSLG LY +++G Sbjct: 199 ----------LYHQGKFLQTFCGSPLYASPEIVNGKPYTGPE--VDSWSLGVLLYILVHG 246 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PF+ G L I N + PP P + W+L P R + D+ Sbjct: 247 TMPFD---GHDHKILVKQISNGAYR-----EPPKPSDACGLIRWLLMVNPTRRATLEDVA 298 Query: 1081 LH 1086 H Sbjct: 299 SH 300
>Q9H093:NUAK2_HUMAN NUAK family SNF1-like kinase 2 - Homo sapiens (Human)| Length = 628 Score = 57.4 bits (137), Expect = 1e-07 Identities = 65/302 (21%), Positives = 116/302 (38%), Gaps = 1/302 (0%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 R+ L +G+G + V +E A + +++K I+ + L ++ Sbjct: 52 RYEFLETLGKGTYGKVKKARESSGRLVAIK-------------SIRKDKIKDEQDLMHIR 98 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 EI + S NHP+++ + H + + S + ++ G L+D + Q E Sbjct: 99 REIEIMSSLNHPHIIAI--HEVF-------ENSSKIVIVMEYASRGDLYDYISERQQLSE 149 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 + F+QI + + H H D+K N+L+ G +A DFG S Sbjct: 150 ----REARHFFRQIVSAVHYCHQ--NRVVHRDLKLENILLDAN-GNIKIA---DFGLSN- 198 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 ++ C +P + +PE+ + + + D WSLG LY +++G Sbjct: 199 ----------LYHQGKFLQTFCGSPLYASPEIVNGKPYTGPE--VDSWSLGVLLYILVHG 246 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PF+ G L I N + PP P + W+L P R + D+ Sbjct: 247 TMPFD---GHDHKILVKQISNGAYR-----EPPKPSDACGLIRWLLMVNPTRRATLEDVA 298 Query: 1081 LH 1086 H Sbjct: 299 SH 300
>P51138:MSK2_MEDSA Glycogen synthase kinase-3 homolog MsK-2 - Medicago sativa (Alfalfa)| Length = 411 Score = 57.4 bits (137), Expect = 1e-07 Identities = 77/319 (24%), Positives = 126/319 (39%), Gaps = 23/319 (7%) Frame = +1 Query: 199 RQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRV 378 R +G+G F V+ K + T A+KKVL R + E++ Sbjct: 78 RAVGQGSFGVVFQAKCLETGE---------------TVAIKKVLQDKRYK----NRELQT 118 Query: 379 SSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVL 558 L +HPN++ L H + +T+ D E YL + S+ L Sbjct: 119 MRLLDHPNVVTL-KHCFFS--TTEKD---ELYLNLVLEFVPETVHRVIRHYSKMNQRMPL 172 Query: 559 DVLRIFQ-QICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQ 735 ++++ QIC L ++H+ +H D+KP N+LV Q L DFGS++ Sbjct: 173 IYVKLYSYQICRSLAYIHNC-VGVSHRDIKPQNLLVNPHTHQLKLC---DFGSAKVL--- 225 Query: 736 IRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE 915 ++ + + CS +RAPEL + DIWS GC L ++ G F Sbjct: 226 -------VKGEPNISYICSRYYRAPEL--IFGATEYTSAIDIWSAGCVLGELLLGQPLFP 276 Query: 916 YALG-----------ESGGSLQLAIMN---AQLKWPQLPSPPYPDALHK--------FVT 1029 A G + ++ MN + K+PQ+ + P+ K V+ Sbjct: 277 GASGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHPWHKIFRKRMPPEAVDLVS 336 Query: 1030 WMLQPQPAMRPHINDILLH 1086 +LQ P +R + L+H Sbjct: 337 RLLQYSPNLRSTALEALVH 355
>O61267:LOK_DROME Ovarian-specific serine/threonine-protein kinase Lok - Drosophila| melanogaster (Fruit fly) Length = 476 Score = 57.4 bits (137), Expect = 1e-07 Identities = 64/277 (23%), Positives = 105/277 (37%), Gaps = 16/277 (5%) Frame = +1 Query: 298 GDGTYAMKKVLIQSRE----QLDLVKEEI----RVSSLFNHPN-------LLPLLDHAII 432 G G Y + +++ +R + +VK+ + R S+ F+ P+ ++ L H + Sbjct: 181 GSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHPCV 240 Query: 433 AVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHS 612 D Y++ G L + + E S L F Q+C +K++H Sbjct: 241 VRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKL----YFYQMCHAVKYLH- 295 Query: 613 LDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCS 792 D H D+KP NVL+ + L + DFG S+ + R+ C Sbjct: 296 -DRGITHRDLKPDNVLL-ETNDEETLLKVSDFGLSKFVQKDSVMRTL-----------CG 342 Query: 793 AP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIMNAQ 969 P + APE+ ++ DIWSLG L+ + G PF E G I + Sbjct: 343 TPLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFS---DEYGTPAAQQIKKGR 399 Query: 970 LKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 + + ML P RP I+D+L Sbjct: 400 FAYGHPSWKSVSQRAKLLINQMLIVDPERRPSIDDVL 436
>Q6PFQ0:KS6A6_DANRE Ribosomal protein S6 kinase alpha-6 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 740 Score = 57.4 bits (137), Expect = 1e-07 Identities = 70/273 (25%), Positives = 119/273 (43%), Gaps = 3/273 (1%) Frame = +1 Query: 184 RFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVK 363 +F +L+ +G+G F V+LV++ DA + YAMK + S + D V+ Sbjct: 66 QFELLKVLGQGSFGKVFLVRKL-MGPDAGQ-----------LYAMKVLKKASLKVRDRVR 113 Query: 364 EEIRVSSLF--NHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSR 537 ++ L NHP ++ L H T+G + YL+ G +F S+ Sbjct: 114 TKMERDILVEVNHPFIVKL--HYAF---QTEG----KLYLILDFLRGGDVFTRL----SK 160 Query: 538 KEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSS 717 + ++ DV ++ L H+H+L Y D+KP N+L+ +A L DFG S Sbjct: 161 EVMFTEEDVKFYLAELALALDHLHNLGIVY--RDLKPENILLD----EAGHIKLTDFGLS 214 Query: 718 RPARNQIRSRSEALRLQEWAAEHC-SAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIM 894 + + +Q + A C + + APE+ + H + D WSLG ++ ++ Sbjct: 215 KESVDQDKK----------AYSFCGTVEYMAPEVVNRRGHT---QSADWWSLGVLMFEML 261 Query: 895 YGVSPFEYALGESGGSLQLAIMNAQLKWPQLPS 993 G PF+ G+ I+ A+L PQ S Sbjct: 262 TGTLPFQ---GKDRNETMNMILKAKLGMPQFLS 291 Score = 55.8 bits (133), Expect = 4e-07 Identities = 58/242 (23%), Positives = 94/242 (38%), Gaps = 1/242 (0%) Frame = +1 Query: 364 EEIRVSSLFN-HPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRK 540 EEI + + HPN++ L D D YL+ + G L D R+ Sbjct: 460 EEIEILMRYGQHPNIITLKDVY---------DEGRFVYLVTELMKGGELLDKIL----RQ 506 Query: 541 EFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR 720 +F+S + + I + + ++H H D+KP N+L G + DFG ++ Sbjct: 507 KFFSEREASAVLYTITKTVDYLHCQG--VVHRDLKPSNILYMDDSGNPDSIRICDFGFAK 564 Query: 721 PARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 Q+R + L + A F APE+ D DIWSLG LY ++ G Sbjct: 565 ----QLRGDNGLLLTPCYTAN-----FVAPEVL---MRQGYDAACDIWSLGVLLYTMLAG 612 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 +PF ++ + L I + + D+ ++ ML P R +L Sbjct: 613 YTPFANGPNDTPEEILLRIGSGKFSLSGGNWDSVSDSSKDLLSHMLHVDPHHRYTAEQVL 672 Query: 1081 LH 1086 H Sbjct: 673 KH 674
>P97756:KKCC1_RAT Calcium/calmodulin-dependent protein kinase kinase 1 - Rattus| norvegicus (Rat) Length = 505 Score = 57.4 bits (137), Expect = 1e-07 Identities = 63/249 (25%), Positives = 103/249 (41%), Gaps = 3/249 (1%) Frame = +1 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 L+ V +EI + +H N++ L++ YL+F + G + + + Sbjct: 193 LERVYQEIAILKKLDHVNVVKLIE-------VLDDPAEDNLYLVFDLLRKGPVME----V 241 Query: 529 QSRKEFYSVLDVLRIF-QQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMD 705 K F + R++ + I GL+++H H D+KP N+L+ G + D Sbjct: 242 PCDKPFPE--EQARLYLRDIILGLEYLHC--QKIVHRDIKPSNLLL----GDDGHVKIAD 293 Query: 706 FGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLY 885 FG S NQ L ++ + F APE + + D+W+ G TLY Sbjct: 294 FGVS----NQFEGNDAQL-----SSTAGTPAFMAPEAISDTGQSFSGKALDVWATGVTLY 344 Query: 886 AIMYGVSPF--EYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 +YG PF EY L +L I N + +P+ P + L + ML P R Sbjct: 345 CFVYGKCPFIDEYIL-----ALHRKIKNEAVVFPE--EPEVSEELKDLILKMLDKNPETR 397 Query: 1060 PHINDILLH 1086 ++DI LH Sbjct: 398 IGVSDIKLH 406
>O88866:HUNK_MOUSE Hormonally up-regulated neu tumor-associated kinase - Mus musculus| (Mouse) Length = 714 Score = 57.4 bits (137), Expect = 1e-07 Identities = 74/300 (24%), Positives = 120/300 (40%), Gaps = 6/300 (2%) Frame = +1 Query: 199 RQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDL-----VK 363 R++GEG FA V R HV A+K V+ + R + D ++ Sbjct: 66 RKLGEGSFAKV---------------REGLHVLTGEKVAIK-VIDKKRAKKDTYVTKNLR 109 Query: 364 EEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKE 543 E ++ + HPN+ LLD + T+ + YL+ + G L K+ Sbjct: 110 REGQIQQMIRHPNITQLLD-----ILETENSY----YLVMELCPGGNLMHKIY----EKK 156 Query: 544 FYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRP 723 + R +Q+ ++H+H H D+K N+L+ L+DFG S Sbjct: 157 RLDEAEARRYIRQLISAVEHLHRAG--VVHRDLKIENLLLDEDNN----IKLIDFGLSNC 210 Query: 724 ARNQIRSRSEALRLQEWAAEHCSAP-FRAPELWDCPSHADIDERTDIWSLGCTLYAIMYG 900 A I S+ Q C +P + APEL + + D+WS+G +YA++ G Sbjct: 211 AG--ILGYSDPFSTQ------CGSPAYAAPELL---ARKKYGPKIDVWSIGVNMYAMLTG 259 Query: 901 VSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDIL 1080 PF Q + A LP+ A++ F+ +L+P P RP+I L Sbjct: 260 TLPFTVEPFSLRALYQKMVDKAM---NPLPTQLSTGAVN-FLRSLLEPDPVKRPNIQQAL 315
>Q9N3Z3:CHK1_CAEEL Serine/threonine-protein kinase chk-1 - Caenorhabditis elegans| Length = 503 Score = 57.4 bits (137), Expect = 1e-07 Identities = 71/259 (27%), Positives = 114/259 (44%), Gaps = 11/259 (4%) Frame = +1 Query: 178 ERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLI--QSREQL 351 E +RV++ +GEG F V L+ AA AMKK+ I +S++ + Sbjct: 21 ESLYRVVQTLGEGAFGEVLLIVNTKNPEVAA--------------AMKKINIANKSKDFI 66 Query: 352 DLVKEEI----RVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLD-GTLFD- 513 D +++E RVS++ H N++ +I +++ + Y LF + D G LFD Sbjct: 67 DNIRKEYLLQKRVSAV-GHDNVI-----RMIGMRN-----DPQFYYLFLEYADGGELFDK 115 Query: 514 ---NAAVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQA 684 + + +FY F+Q+ GLK +H D H D+KP N+L+T Sbjct: 116 IEPDCGMSPVFAQFY--------FKQLICGLKFIH--DNDVVHRDIKPENLLLT----GT 161 Query: 685 PLATLMDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIW 864 + + DFG + RN+ R L + P+ APEL C D+W Sbjct: 162 HVLKISDFGMATLYRNKGEERLLDLSCG-------TIPYAAPEL--CAGKKYRGPPVDVW 212 Query: 865 SLGCTLYAIMYGVSPFEYA 921 S G L A++ G P++ A Sbjct: 213 SSGIVLIAMLTGELPWDRA 231
>P62343:CDPK1_PLAFK Calcium-dependent protein kinase 1 - Plasmodium falciparum (isolate| K1 / Thailand) Length = 524 Score = 57.4 bits (137), Expect = 1e-07 Identities = 65/250 (26%), Positives = 103/250 (41%), Gaps = 3/250 (1%) Frame = +1 Query: 172 INERRFRVLRQIGEGGFAFVYLVKE-HDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQ 348 I E F+V R++G G + V L +E H A + S MK + E Sbjct: 52 IGESYFKV-RKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFD-----KMKYSITNKIEC 105 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 D + EEI +N +LL LDH I + YL+ + G LF+ Sbjct: 106 DDKIHEEI-----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-- 158 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + + D I +QI G+ ++H + H D+KP N+L+ + + ++DF Sbjct: 159 --NRHKFDECDAANIMKQILSGICYLHKHN--IVHRDIKPENILLENKHSLLNIK-IVDF 213 Query: 709 GSSR--PARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTL 882 G S N++R R +A + APE+ +E+ D+WS G L Sbjct: 214 GLSSFFSKDNKLRDRLG------------TAYYIAPEVL----RKKYNEKCDVWSCGVIL 257 Query: 883 YAIMYGVSPF 912 Y ++ G PF Sbjct: 258 YILLCGYPPF 267
>P62344:CDPK1_PLAF7 Calcium-dependent protein kinase 1 - Plasmodium falciparum (isolate| 3D7) Length = 524 Score = 57.4 bits (137), Expect = 1e-07 Identities = 65/250 (26%), Positives = 103/250 (41%), Gaps = 3/250 (1%) Frame = +1 Query: 172 INERRFRVLRQIGEGGFAFVYLVKE-HDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQ 348 I E F+V R++G G + V L +E H A + S MK + E Sbjct: 52 IGESYFKV-RKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFD-----KMKYSITNKIEC 105 Query: 349 LDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 D + EEI +N +LL LDH I + YL+ + G LF+ Sbjct: 106 DDKIHEEI-----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-- 158 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 + + D I +QI G+ ++H + H D+KP N+L+ + + ++DF Sbjct: 159 --NRHKFDECDAANIMKQILSGICYLHKHN--IVHRDIKPENILLENKHSLLNIK-IVDF 213 Query: 709 GSSR--PARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTL 882 G S N++R R +A + APE+ +E+ D+WS G L Sbjct: 214 GLSSFFSKDNKLRDRLG------------TAYYIAPEVL----RKKYNEKCDVWSCGVIL 257 Query: 883 YAIMYGVSPF 912 Y ++ G PF Sbjct: 258 YILLCGYPPF 267
>Q6NW76:AURKB_DANRE Serine/threonine-protein kinase 12 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 320 Score = 57.4 bits (137), Expect = 1e-07 Identities = 75/307 (24%), Positives = 125/307 (40%), Gaps = 7/307 (2%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLV-- 360 F + R +G+G F VYL +E A KVL +S+ + V Sbjct: 53 FDIGRPLGKGKFGNVYLARERKLKVVIAL----------------KVLFKSQMVKEGVEH 96 Query: 361 --KEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQS 534 + EI + S HPN+L ++ H+ +F + + M Sbjct: 97 QLRREIEIQSHLRHPNILRFYNYF------------HDDTRVFLI----LEYAPRGEMYK 140 Query: 535 RKEFYSVLDVLRI---FQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMD 705 + Y D R +++ + L++ H + H D+KP N+L+ +G+ +A D Sbjct: 141 ELQRYGRFDDQRTATYMEEVSDALQYCH--EKKVIHRDIKPENLLLG-YRGELKIA---D 194 Query: 706 FGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLY 885 FG S A + +R R+ L + PE+ + SH DE+ D+WS+G Y Sbjct: 195 FGWSVHAPS-LRRRTMCGTLD----------YLPPEMIEGHSH---DEKVDLWSIGVLCY 240 Query: 886 AIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPH 1065 + G PFE A S I L++P+L S D + K +L+ P+MR Sbjct: 241 ECLVGNPPFETA---SHAETYKRITKVDLQFPKLVSEGARDLISK----LLRHSPSMRLP 293 Query: 1066 INDILLH 1086 + ++ H Sbjct: 294 LRSVMEH 300
>O55098:STK10_MOUSE Serine/threonine-protein kinase 10 - Mus musculus (Mouse)| Length = 966 Score = 57.0 bits (136), Expect = 2e-07 Identities = 76/312 (24%), Positives = 123/312 (39%), Gaps = 4/312 (1%) Frame = +1 Query: 163 DVWINERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSR 342 DVW ++ ++G+G F VY K + + AA K + +S Sbjct: 34 DVW------EIVGELGDGAFGKVYKAKNKETGALAAA---------------KVIETKSE 72 Query: 343 EQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHL-DGTLFDNA 519 E+L+ EI + + +HP ++ LL G + ++ L + G D Sbjct: 73 EELEDYIVEIEILATCDHPYIVKLL-----------GAYYYDGKLWIMIEFCPGGAVD-- 119 Query: 520 AVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATL 699 A+M + + + +Q+ E L +H H D+K GNVL+T + G LA Sbjct: 120 AIMLELDRGLTEPQIQVVCRQMLEALNFLHG--KRIIHRDLKAGNVLMTLE-GDIRLA-- 174 Query: 700 MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADI--DERTDIWSLG 873 DFG S ++ R + W A PE+ C + D D + DIWSLG Sbjct: 175 -DFGVSAKNLKTLQKRDSFIGTPYWMA---------PEVVLCETMKDAPYDYKADIWSLG 224 Query: 874 CTLYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSP-PYPDALHKFVTWMLQPQP 1050 TL M + P + L +++ + A+ P L +P + F+ L P Sbjct: 225 ITLIE-MAQIEPPHHEL----NPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNP 279 Query: 1051 AMRPHINDILLH 1086 RP +L H Sbjct: 280 ETRPSAAQLLQH 291
>Q9IA88:SN1L2_CHICK Serine/threonine-protein kinase SNF1-like kinase 2 - Gallus gallus| (Chicken) Length = 798 Score = 57.0 bits (136), Expect = 2e-07 Identities = 69/309 (22%), Positives = 126/309 (40%), Gaps = 9/309 (2%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSR---EQLDL 357 + + R +G+G FA V L + + A K++ ++R L+ Sbjct: 26 YDIERTLGKGNFAVVKLARHRVTKTQVAI----------------KIIDKTRLDPSNLEK 69 Query: 358 VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNA------ 519 + E+++ L NHP+++ L + ++ K Y++ +G +FD+ Sbjct: 70 IYREVQIMKLLNHPHIIKL--YQVMETKDM-------LYIVTEFAKNGEMFDHLTSNGHL 120 Query: 520 AVMQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATL 699 + ++RK+F+ +L + + C H H + H D+K N+L+ L Sbjct: 121 SESEARKKFWQILSAV----EYC----HSHHI----VHRDLKTENLLLDANMN----IKL 164 Query: 700 MDFGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCT 879 DFG N +S L W S P+ APE+++ + DIWSLG Sbjct: 165 ADFGFG----NFYKSGEP---LSTWCG---SPPYAAPEVFEGKEYEG--PHLDIWSLGVV 212 Query: 880 LYAIMYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMR 1059 LY ++ G PF+ G + +L+ ++ + + P S + + ML P R Sbjct: 213 LYVLVCGSLPFD---GPNLPTLRQRVLEGRFRIPYFMS----EDCETLIRRMLVVDPTKR 265 Query: 1060 PHINDILLH 1086 I+ I H Sbjct: 266 ITISQIKQH 274
>Q3UGM2:NEK10_MOUSE Serine/threonine-protein kinase Nek10 - Mus musculus (Mouse)| Length = 1111 Score = 57.0 bits (136), Expect = 2e-07 Identities = 61/308 (19%), Positives = 119/308 (38%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 + VL +G G F VY V++ + A H G K + ++V E Sbjct: 519 YAVLDHLGSGAFGCVYKVRKRSGQNLLAMKEVNLHNPAFG----KDKKDRDSSVKNIVSE 574 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 + HPN++ + + Y++ + L ++ ++ + Sbjct: 575 LTIIKEQLYHPNVVRYYKTFLE---------NDRLYIVMELIEGAPLGEHFNSLKEKHHH 625 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 +S + +IF Q+C L+++H + H D+ P N+++ G T+ DFG ++ Sbjct: 626 FSEERLWKIFIQLCLALRYLHK-EKRIVHRDLTPNNIML----GDKDKVTVTDFGLAK-- 678 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 + E+ +L + + PE+ + E+ D+W+ GC LY + Sbjct: 679 -----QKQESSKLTSMVG---TILYSCPEVLKSEPYG---EKADVWAAGCILYQMATLSP 727 Query: 907 PFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 PF S L LA + + +P Y + + + L P RP I ++ Sbjct: 728 PF-----CSTNMLSLATKIVEAVYEPVPEGIYSEKVTDTIRRCLTPDAEARPDIVEVSSM 782 Query: 1087 VDKLVEKY 1110 + ++ KY Sbjct: 783 ISDVMMKY 790
>Q80Y86:MK15_MOUSE Mitogen-activated protein kinase 15 - Mus musculus (Mouse)| Length = 549 Score = 57.0 bits (136), Expect = 2e-07 Identities = 69/250 (27%), Positives = 109/250 (43%), Gaps = 10/250 (4%) Frame = +1 Query: 181 RRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDL- 357 +R+ + R++G+G + V+ A DR V A+KK+ R+Q+D Sbjct: 12 QRYLIKRRLGKGAYGIVW----------KAMDRRTGEV-----VAIKKIFDAFRDQIDAQ 56 Query: 358 --VKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQ 531 +E + + HPN++ LLD +I K+ + + YL+F +D L NA + + Sbjct: 57 RTFREIMLLKEFGGHPNIIRLLD--VIPAKNDR-----DIYLVFE-SMDTDL--NAVIQK 106 Query: 532 SRKEFYSVLDVLR--IFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMD 705 R + D+ + IF Q+ K +HS H D KP NVL+ A L D Sbjct: 107 GRL----LKDIHKRCIFYQLLRATKFIHS--GRVIHRDQKPANVLLD----SACRVKLCD 156 Query: 706 FGSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPEL-----WDCPSHADIDERTDIWSL 870 FG +R + + L E+ A +RAPE+ W P D+WSL Sbjct: 157 FGLAR-SLGDLPEGPGGQALTEYVATRW---YRAPEVLLSSRWYTPG-------VDMWSL 205 Query: 871 GCTLYAIMYG 900 GC L ++ G Sbjct: 206 GCILGEMLRG 215
>P24719:MEK1_YEAST Meiosis-specific serine/threonine-protein kinase MEK1 - Saccharomyces| cerevisiae (Baker's yeast) Length = 497 Score = 57.0 bits (136), Expect = 2e-07 Identities = 81/329 (24%), Positives = 133/329 (40%), Gaps = 12/329 (3%) Frame = +1 Query: 199 RQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRV 378 R +G G F V L+ + D HP + YA+K + ++ + +E R+ Sbjct: 166 RIVGNGTFGHV-LITHNSKERDEDVCYHPEN------YAVKIIKLKPNK----FDKEARI 214 Query: 379 SSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSVL 558 +HPN II V T D ++ Y+ + G LF A Sbjct: 215 LLRLDHPN--------IIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETE 266 Query: 559 DVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQI 738 +L +FQ I + L ++H D H D+K N+L+ + + L DFG ++ + Sbjct: 267 SLLIVFQ-ILQALNYLHDQD--IVHRDLKLDNILLCTPEPCTRIV-LADFGIAK----DL 318 Query: 739 RSRSEALRLQEWAAEHCSAP--FRAP-ELWDCPSHA------DIDERTDIWSLGCTLYAI 891 S E + E+C+ FRA + + S A D + D+WSLG + + Sbjct: 319 NSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIM 378 Query: 892 MYGVSPFEYALGESGGSLQ---LAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRP 1062 + G+SPF Y G +Q + +N +LK + S D FV +LQ R Sbjct: 379 LTGISPF-YGDGSERSIIQNAKIGKLNFKLKQWDIVS----DNAKSFVKDLLQTDVVKRL 433 Query: 1063 HINDILLHVDKLVEKYSP*SQLAYSVLTC 1149 + L H+ + + S +L Y + C Sbjct: 434 NSKQGLKHI-WIAKHLSQLERLYYKKILC 461
>Q05512:MARK2_MOUSE Serine/threonine-protein kinase MARK2 - Mus musculus (Mouse)| Length = 776 Score = 57.0 bits (136), Expect = 2e-07 Identities = 69/281 (24%), Positives = 116/281 (41%), Gaps = 1/281 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 +R+L+ IG+G FA V L + + A + K + S L + Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVA------------VKIIDKTQLNS-SSLQKLFR 99 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 E+R+ + NHPN++ L + +I + T YL+ G +FD KE Sbjct: 100 EVRIMKVLNHPNIVKLFE--VIETEKT-------LYLVMEYASGGEVFDYLVAHGRMKE- 149 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 + F+QI +++ H H D+K N+L+ + DFG S Sbjct: 150 ---KEARAKFRQIVSAVQYCHQKF--IVHRDLKAENLLLDADMN----IKIADFGFS--- 197 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADID-ERTDIWSLGCTLYAIMYGV 903 N+ + +L + S P+ APEL+ ID D+WSLG LY ++ G Sbjct: 198 -NEFTFGN---KLDTFCG---SPPYAAPELFQGKK---IDGPEVDVWSLGVILYTLVSGS 247 Query: 904 SPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFV 1026 PF+ G++ L+ ++ + + P S + L KF+ Sbjct: 248 LPFD---GQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 285
>Q99JP0:M4K3_MOUSE Mitogen-activated protein kinase kinase kinase kinase 3 - Mus| musculus (Mouse) Length = 894 Score = 57.0 bits (136), Expect = 2e-07 Identities = 67/312 (21%), Positives = 116/312 (37%), Gaps = 12/312 (3%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F ++++IG G + VY + + AA +K + ++ E +V++ Sbjct: 16 FELIQRIGSGTYGDVYKARNVNTGELAA---------------IKVIKLEPGEDFAVVQQ 60 Query: 367 EIRVSSLFNHPNLLPLL------DHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVM 528 EI + HPN++ D I ++ G + Y H+ G L Sbjct: 61 EIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIY-----HVTGPL------- 108 Query: 529 QSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDF 708 S L + + ++ +GL ++HS H D+K N+L+T G LA DF Sbjct: 109 -------SELQIAYVSRETLQGLYYLHSKGK--MHRDIKGANILLT-DNGHVKLA---DF 155 Query: 709 GSSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYA 888 G S I R + W A PE+ ++ D+W++G T Sbjct: 156 GVSAQITATIAKRKSFIGTPYWMA---------PEVAAVERKGGYNQLCDLWAVGITAIE 206 Query: 889 I------MYGVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQP 1050 + M+ + P + + Q + +LKW ++ H FV L P Sbjct: 207 LAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWS--------NSFHHFVKMALTKNP 258 Query: 1051 AMRPHINDILLH 1086 RP+ +L H Sbjct: 259 KKRPNAEKLLQH 270
>Q96287:KSG8_ARATH Shaggy-related protein kinase theta - Arabidopsis thaliana (Mouse-ear| cress) Length = 472 Score = 57.0 bits (136), Expect = 2e-07 Identities = 77/316 (24%), Positives = 124/316 (39%), Gaps = 29/316 (9%) Frame = +1 Query: 199 RQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRV 378 R +G G F V+ K + A +KKVL R + E+++ Sbjct: 142 RVVGTGSFGVVFQAKCLETGEQVA---------------IKKVLQDKRYK----NRELQI 182 Query: 379 SSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYL-LFPVHLDGTLFDNAAVMQSRKEFYSV 555 L +HPN++ L H+ + +T D E YL L ++ T++ + + + Sbjct: 183 MRLQDHPNVVRLR-HSFFS--TTDKD---ELYLNLVLEYVPETVYRASKHYTKMNQHMPI 236 Query: 556 LDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR---PA 726 + V QIC L ++H + H D+KP N+LV Q Q + DFGS++ P Sbjct: 237 IFVQLYTYQICRALNYLHRV-VGVCHRDIKPQNLLVNPQTHQLKIC---DFGSAKMLVPG 292 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 I + CS +RAPEL + D+WS GC + ++ G Sbjct: 293 EPNI-------------SYICSRYYRAPEL--IFGATEYTNAIDMWSGGCVMAELLLGQP 337 Query: 907 PFEYALGESGGSLQLAIMN-----------------AQLKWPQLPSPPYPDALHK----- 1020 F GESG + I+ + K+PQ+ + P+ HK Sbjct: 338 LFP---GESGIDQLVEIIKILGTPTREEIRCMNPNYTEFKFPQIKAHPWHKIFHKRMPPE 394 Query: 1021 ---FVTWMLQPQPAMR 1059 V+ +LQ P +R Sbjct: 395 AVDLVSRLLQYSPNLR 410
>Q8C050:KS6A5_MOUSE Ribosomal protein S6 kinase alpha-5 - Mus musculus (Mouse)| Length = 863 Score = 57.0 bits (136), Expect = 2e-07 Identities = 48/183 (26%), Positives = 79/183 (43%), Gaps = 3/183 (1%) Frame = +1 Query: 376 VSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSV 555 V S P L P + ++ + + H +L+ + G LF+ RK+ +S Sbjct: 528 VHSTSQLPPLPPPMPEIVLFILLSDNGQLH-TFLVMELLNGGELFERI----KRKKHFSE 582 Query: 556 LDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR---PA 726 + I +++ + HMH D H D+KP N+L T + + + DFG +R P Sbjct: 583 TEASYIMRKLVSAVSHMH--DVGVVHRDLKPENLLFTDENDNLEIKVI-DFGFARLKPPD 639 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 +++ L + APEL +H DE D+WSLG LY ++ G Sbjct: 640 NQPLKTPCFTLH------------YAAPELL---THNGYDESCDLWSLGVILYTMLSGQV 684 Query: 907 PFE 915 PF+ Sbjct: 685 PFQ 687 Score = 44.3 bits (103), Expect = 0.001 Identities = 66/290 (22%), Positives = 114/290 (39%), Gaps = 10/290 (3%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKE---HDASSDAARDRHPSHVSGDGTYAMKKV----LIQSRE 345 F +L+ +G G + V+LV++ HDA YAMK + ++Q + Sbjct: 48 FELLKVLGTGAYGKVFLVRKISGHDAGK---------------LYAMKVLKKATIVQKAK 92 Query: 346 QLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAV 525 + + E +V L L +A + +L+ G LF + Sbjct: 93 TTEHTRTERQVLEHIRQSPFLVTLHYAF--------QTETKLHLILDYINGGELFTHL-- 142 Query: 526 MQSRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMD 705 S++E ++ +V +I L+H+H L Y D+K N+L+ L D Sbjct: 143 --SQRERFTEHEVQIYVGEIVLALEHLHKLGIIY--RDIKLENILLDSNGH----VVLTD 194 Query: 706 FGSSRPARNQIRSRSEALRLQEWAAEHCSA-PFRAPELWDCPSHADIDERTDIWSLGCTL 882 FG S+ R A C + AP++ + D+ D WSLG + Sbjct: 195 FGLSKEFVADETER---------AYSFCGTIEYMAPDIVR-GGDSGHDKAVDWWSLGVLM 244 Query: 883 YAIMYGVSPFEYALGESGGSLQLA--IMNAQLKWPQLPSPPYPDALHKFV 1026 Y ++ G SPF GE +++ I+ ++ +PQ S D L + + Sbjct: 245 YELLTGASPFTVD-GEKNSQAEISRRILKSEPPYPQEMSTVAKDLLQRLL 293
>P53684:CDPK3_ORYSJ Calcium-dependent protein kinase, isoform 11 - Oryza sativa subsp.| japonica (Rice) Length = 542 Score = 57.0 bits (136), Expect = 2e-07 Identities = 70/298 (23%), Positives = 119/298 (39%), Gaps = 2/298 (0%) Frame = +1 Query: 199 RQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKEEIRV 378 R++G+G F YL E + + A P K+ LI ++E ++ V+ EI++ Sbjct: 83 RKLGQGQFGTTYLCTEINTGCEYACKTIP-----------KRKLI-TKEDVEDVRREIQI 130 Query: 379 SS-LFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEFYSV 555 L H N ++A+K D +++ + G LFD K YS Sbjct: 131 MHHLSGHKN--------VVAIKDVYED-GQAVHIVMELCAGGELFDRI----QEKGHYSE 177 Query: 556 LDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPARNQ 735 + + I + HSL H D+KP N L+ + + + DFG S Sbjct: 178 RKAAELIRIIVSIVAMCHSLG--VMHRDLKPENFLLLDKDDDLSIKAI-DFGLS------ 228 Query: 736 IRSRSEALRLQEWAAEHCSAPFR-APELWDCPSHADIDERTDIWSLGCTLYAIMYGVSPF 912 + + E +P+ APE+ H +D+WS G LY ++ GV PF Sbjct: 229 -----VFFKPGQVFTELVGSPYYVAPEVL----HKRYGPESDVWSAGVILYVLLSGVPPF 279 Query: 913 EYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 E+ + A++ + + P P D+ + ML P+ R +++L H Sbjct: 280 ---WAETQQGIFDAVLKGHIDFQSDPWPKISDSAKDLIRKMLSHCPSERLKAHEVLRH 334
>Q7RAH3:CDPK1_PLAYO Calcium-dependent protein kinase 1 - Plasmodium yoelii yoelii| Length = 535 Score = 57.0 bits (136), Expect = 2e-07 Identities = 60/247 (24%), Positives = 99/247 (40%) Frame = +1 Query: 172 INERRFRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQL 351 I E F+V R++G G + V L KE + S+ A G Y + + Sbjct: 53 IGESYFKV-RKLGSGAYGEVLLCKEKNGHSEKAIKVIKKSQFDKGRYN------DDNKNI 105 Query: 352 DLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQ 531 + EEI +N +LL LDH I + YL+ + G LF+ Sbjct: 106 EKFHEEI-----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII--- 157 Query: 532 SRKEFYSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFG 711 + + D I +QI G+ ++H + H D+KP N+L+ + + ++DFG Sbjct: 158 -NRHKFDECDAANIMKQILSGICYLHKHN--IVHRDIKPENILLENKNSLLNIK-IVDFG 213 Query: 712 SSRPARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAI 891 S + R +A + APE+ +E+ D+WS G +Y + Sbjct: 214 LSSFFSKDYKLRDRL----------GTAYYIAPEVLK----KKYNEKCDVWSCGVIMYIL 259 Query: 892 MYGVSPF 912 + G PF Sbjct: 260 LCGYPPF 266
>O14965:STK6_HUMAN Serine/threonine-protein kinase 6 - Homo sapiens (Human)| Length = 403 Score = 56.6 bits (135), Expect = 2e-07 Identities = 64/300 (21%), Positives = 114/300 (38%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 F + R +G+G F VYL +E + A + K ++ ++ Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALK------------VLFKAQLEKAGVEHQLRR 180 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 E+ + S HPN+L L + A + YL+ GT++ + E Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATR---------VYLILEYAPLGTVYRELQKLSKFDEQ 231 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSRPA 726 + + ++ L + HS H D+KP N+L+ G A + DFG S A Sbjct: 232 RTATYIT----ELANALSYCHS--KRVIHRDIKPENLLL----GSAGELKIADFGWSVHA 281 Query: 727 RNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMYGVS 906 + R+ + + PE+ + H DE+ D+WSLG Y + G Sbjct: 282 PSSRRTTLCG-----------TLDYLPPEMIEGRMH---DEKVDLWSLGVLCYEFLVGKP 327 Query: 907 PFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 PFE + I + +P + + ++ +L+ P+ RP + ++L H Sbjct: 328 PFE---ANTYQETYKRISRVEFTFPDFVT----EGARDLISRLLKHNPSQRPMLREVLEH 380
>Q5R495:OXSR1_PONPY Serine/threonine-protein kinase OSR1 - Pongo pygmaeus (Orangutan)| Length = 527 Score = 56.6 bits (135), Expect = 2e-07 Identities = 63/279 (22%), Positives = 118/279 (42%), Gaps = 21/279 (7%) Frame = +1 Query: 313 AMKKVLIQS-REQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPV 489 A+K++ ++ + +D + +EI+ S +HPN++ ++ E +L+ + Sbjct: 44 AIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVV---------KDELWLVMKL 94 Query: 490 HLDGTLFDNAAVMQSRKEFYS-VLD---VLRIFQQICEGLKHMHSLDPPYAHNDVKPGNV 657 G++ D + ++ E S VLD + I +++ EGL+++H H DVK GN+ Sbjct: 95 LSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQ--IHRDVKAGNI 152 Query: 658 LVTRQKGQAPLATLMDFGSSR-------PARNQIRSRSEALRLQEWAAEHCSAPFRAPEL 816 L+ G+ + DFG S RN++R + + C + APE+ Sbjct: 153 LL----GEDGSVQIADFGVSAFLATGGDITRNKVR--------KTFVGTPC---WMAPEV 197 Query: 817 WDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE---------YALGESGGSLQLAIMNAQ 969 + D + DIWS G T + G +P+ L SL+ + + + Sbjct: 198 ME--QVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKE 255 Query: 970 LKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 + Y + K ++ LQ P RP ++L H Sbjct: 256 M------LKKYGKSFRKMISLCLQKDPEKRPTAAELLRH 288
>Q863I2:OXSR1_PIG Serine/threonine-protein kinase OSR1 - Sus scrofa (Pig)| Length = 529 Score = 56.6 bits (135), Expect = 2e-07 Identities = 63/279 (22%), Positives = 118/279 (42%), Gaps = 21/279 (7%) Frame = +1 Query: 313 AMKKVLIQS-REQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPV 489 A+K++ ++ + +D + +EI+ S +HPN++ ++ E +L+ + Sbjct: 44 AIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVV---------KDELWLVMKL 94 Query: 490 HLDGTLFDNAAVMQSRKEFYS-VLD---VLRIFQQICEGLKHMHSLDPPYAHNDVKPGNV 657 G++ D + ++ E S VLD + I +++ EGL+++H H DVK GN+ Sbjct: 95 LSGGSVLDIIKHIVAKGEHKSGVLDEATIATILREVLEGLEYLHKNGQ--IHRDVKAGNI 152 Query: 658 LVTRQKGQAPLATLMDFGSSR-------PARNQIRSRSEALRLQEWAAEHCSAPFRAPEL 816 L+ G+ + DFG S RN++R + + C + APE+ Sbjct: 153 LL----GEDGSVQIADFGVSAFLATGGDITRNKVR--------KTFVGTPC---WMAPEV 197 Query: 817 WDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE---------YALGESGGSLQLAIMNAQ 969 + D + DIWS G T + G +P+ L SL+ + + + Sbjct: 198 ME--QVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKE 255 Query: 970 LKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 + Y + K ++ LQ P RP ++L H Sbjct: 256 M------LKKYGKSFRKMISLCLQKDPEKRPTAAELLRH 288
>Q6P9R2:OXSR1_MOUSE Serine/threonine-protein kinase OSR1 - Mus musculus (Mouse)| Length = 527 Score = 56.6 bits (135), Expect = 2e-07 Identities = 63/279 (22%), Positives = 118/279 (42%), Gaps = 21/279 (7%) Frame = +1 Query: 313 AMKKVLIQS-REQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPV 489 A+K++ ++ + +D + +EI+ S +HPN++ ++ E +L+ + Sbjct: 44 AIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVV---------KDELWLVMKL 94 Query: 490 HLDGTLFDNAAVMQSRKEFYS-VLD---VLRIFQQICEGLKHMHSLDPPYAHNDVKPGNV 657 G++ D + ++ E S VLD + I +++ EGL+++H H DVK GN+ Sbjct: 95 LSGGSVLDIIKHIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKNGQ--IHRDVKAGNI 152 Query: 658 LVTRQKGQAPLATLMDFGSSR-------PARNQIRSRSEALRLQEWAAEHCSAPFRAPEL 816 L+ G+ + DFG S RN++R + + C + APE+ Sbjct: 153 LL----GEDGSVQIADFGVSAFLATGGDITRNKVR--------KTFVGTPC---WMAPEV 197 Query: 817 WDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE---------YALGESGGSLQLAIMNAQ 969 + D + DIWS G T + G +P+ L SL+ + + + Sbjct: 198 ME--QVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKE 255 Query: 970 LKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 + Y + K ++ LQ P RP ++L H Sbjct: 256 M------LKKYGKSFRKMISLCLQKDPEKRPTAAELLRH 288
>O95747:OXSR1_HUMAN Serine/threonine-protein kinase OSR1 - Homo sapiens (Human)| Length = 527 Score = 56.6 bits (135), Expect = 2e-07 Identities = 63/279 (22%), Positives = 118/279 (42%), Gaps = 21/279 (7%) Frame = +1 Query: 313 AMKKVLIQS-REQLDLVKEEIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPV 489 A+K++ ++ + +D + +EI+ S +HPN++ ++ E +L+ + Sbjct: 44 AIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVV---------KDELWLVMKL 94 Query: 490 HLDGTLFDNAAVMQSRKEFYS-VLD---VLRIFQQICEGLKHMHSLDPPYAHNDVKPGNV 657 G++ D + ++ E S VLD + I +++ EGL+++H H DVK GN+ Sbjct: 95 LSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQ--IHRDVKAGNI 152 Query: 658 LVTRQKGQAPLATLMDFGSSR-------PARNQIRSRSEALRLQEWAAEHCSAPFRAPEL 816 L+ G+ + DFG S RN++R + + C + APE+ Sbjct: 153 LL----GEDGSVQIADFGVSAFLATGGDITRNKVR--------KTFVGTPC---WMAPEV 197 Query: 817 WDCPSHADIDERTDIWSLGCTLYAIMYGVSPFE---------YALGESGGSLQLAIMNAQ 969 + D + DIWS G T + G +P+ L SL+ + + + Sbjct: 198 ME--QVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKE 255 Query: 970 LKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDILLH 1086 + Y + K ++ LQ P RP ++L H Sbjct: 256 M------LKKYGKSFRKMISLCLQKDPEKRPTAAELLRH 288
>Q5VST9:OBSCN_HUMAN Obscurin - Homo sapiens (Human)| Length = 7968 Score = 56.6 bits (135), Expect = 2e-07 Identities = 71/303 (23%), Positives = 118/303 (38%), Gaps = 3/303 (0%) Frame = +1 Query: 187 FRVLRQIGEGGFAFVYLVKEHDASSDAARDRHPSHVSGDGTYAMKKVLIQSREQLDLVKE 366 + V +IG G F FV V+ H A K + ++SR + +E Sbjct: 6468 YEVKEEIGRGVFGFVKRVQ---------------HKGNKILCAAKFIPLRSRTRAQAYRE 6512 Query: 367 EIRVSSLFNHPNLLPLLDHAIIAVKSTQGDWSHEAYLLFPVHLDGTLFDNAAVMQSRKEF 546 +++L +HP + LLD Q + L+ + L D RK Sbjct: 6513 RDILAAL-SHPLVTGLLD---------QFETRKTLILILELCSSEELLDRLY----RKGV 6558 Query: 547 YSVLDVLRIFQQICEGLKHMHSLDPPYAHNDVKPGNVLVTRQKGQAPLATLMDFGSSR-- 720 + +V Q++ EGL ++HS H D+KP N+L+ + + DFG ++ Sbjct: 6559 VTEAEVKVYIQELVEGLHYLHSHG--VLHLDIKPSNILMVHPARED--IKICDFGFAQNI 6614 Query: 721 -PARNQIRSRSEALRLQEWAAEHCSAPFRAPELWDCPSHADIDERTDIWSLGCTLYAIMY 897 PA Q +++ S F +PE+ + E +DIW++G Y + Sbjct: 6615 TPAELQF-------------SQYGSPEFVSPEIIQ---QNPVSEASDIWAMGVISYLSLT 6658 Query: 898 GVSPFEYALGESGGSLQLAIMNAQLKWPQLPSPPYPDALHKFVTWMLQPQPAMRPHINDI 1077 SPF GES + L ++ ++ W + + F+ LQ P RP Sbjct: 6659 CSSPF---AGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQC 6715 Query: 1078 LLH 1086 L H Sbjct: 6716 LSH 6718 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 244,081,444 Number of extensions: 5588123 Number of successful extensions: 18510 Number of sequences better than 10.0: 1756 Number of HSP's gapped: 17381 Number of HSP's successfully gapped: 1797 Length of query: 451 Length of database: 100,686,439 Length adjustment: 117 Effective length of query: 334 Effective length of database: 68,593,924 Effective search space: 22910370616 Effective search space used: 22910370616 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
