Clone Information

BLAST Search Result

Clone Name	FLbaf16o14
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	Q42954:KPYC_TOBAC Pyruvate kinase, cytosolic isozyme - Nicotiana...	207	4e-90
2	Q42806:KPYC_SOYBN Pyruvate kinase, cytosolic isozyme - Glycine m...	210	5e-90
3	P22200:KPYC_SOLTU Pyruvate kinase, cytosolic isozyme - Solanum t...	208	2e-89
4	O65595:KPYC_ARATH Probable pyruvate kinase, cytosolic isozyme - ...	202	6e-88
5	Q12669:KPYK_ASPNG Pyruvate kinase - Aspergillus niger	169	8e-67
6	P11980:KPYM_RAT Pyruvate kinase isozymes M1/M2 - Rattus norvegic...	165	1e-64
7	Q8Z6K2:KPYK1_SALTI Pyruvate kinase I - Salmonella typhi	150	2e-64
8	P77983:KPYK1_SALTY Pyruvate kinase I - Salmonella typhimurium	149	5e-64
9	P22360:KPYK_EMENI Pyruvate kinase - Emericella nidulans (Aspergi...	169	6e-64
10	Q92122:KPYK_XENLA Pyruvate kinase muscle isozyme - Xenopus laevi...	162	1e-63
11	P11979:KPYM_FELCA Pyruvate kinase isozyme M1 - Felis silvestris ...	162	2e-63
12	P31865:KPYK_TRIRE Pyruvate kinase - Trichoderma reesei (Hypocrea...	160	4e-63
13	O94122:KPYK_AGABI Pyruvate kinase - Agaricus bisporus (Common mu...	162	4e-63
14	Q5NVN0:KPYM_PONPY Pyruvate kinase isozyme M1 - Pongo pygmaeus (O...	160	5e-63
15	P14618:KPYM_HUMAN Pyruvate kinase isozymes M1/M2 - Homo sapiens ...	158	1e-62
16	Q7RVA8:KPYK_NEUCR Pyruvate kinase - Neurospora crassa	157	1e-62
17	P30614:KPYK_YARLI Pyruvate kinase - Yarrowia lipolytica (Candida...	172	1e-62
18	P11974:KPYM_RABIT Pyruvate kinase isozymes M1/M2 - Oryctolagus c...	161	2e-62
19	P52480:KPYM_MOUSE Pyruvate kinase isozymes M1/M2 - Mus musculus ...	157	3e-62
20	P00548:KPYK_CHICK Pyruvate kinase muscle isozyme - Gallus gallus...	163	6e-62
21	Q6FV12:KPYK2_CANGA Pyruvate kinase 2 - Candida glabrata (Yeast) ...	155	4e-61
22	P30613:KPYR_HUMAN Pyruvate kinase isozymes R/L - Homo sapiens (H...	160	6e-61
23	P12928:KPYR_RAT Pyruvate kinase isozymes R/L - Rattus norvegicus...	158	1e-60
24	Q29536:KPYR_CANFA Pyruvate kinase isozyme R - Canis familiaris (...	162	1e-60
25	Q10208:KPYK_SCHPO Pyruvate kinase - Schizosaccharomyces pombe (F...	155	3e-60
26	P53657:KPYR_MOUSE Pyruvate kinase isozymes R/L - Mus musculus (M...	159	2e-59
27	Q875S4:KPYK_SACKL Pyruvate kinase - Saccharomyces kluyveri (Yeas...	155	2e-58
28	Q875M9:KPYK_KLULA Pyruvate kinase - Kluyveromyces lactis (Yeast)...	155	4e-58
29	P00549:KPYK1_YEAST Pyruvate kinase 1 - Saccharomyces cerevisiae ...	155	5e-58
30	Q759A9:KPYK_ASHGO Pyruvate kinase - Ashbya gossypii (Yeast) (Ere...	156	6e-58
31	P52489:KPYK2_YEAST Pyruvate kinase 2 - Saccharomyces cerevisiae ...	153	2e-57
32	Q6FIS9:KPYK1_CANGA Pyruvate kinase 1 - Candida glabrata (Yeast) ...	154	2e-57
33	Q6BS75:KPYK_DEBHA Pyruvate kinase - Debaryomyces hansenii (Yeast...	152	7e-57
34	Q875Z9:KPYK_SACCA Pyruvate kinase - Saccharomyces castellii (Yeast)	150	3e-56
35	O44006:KPYK_EIMTE Pyruvate kinase - Eimeria tenella	189	7e-47
36	Q27686:KPYK_LEIME Pyruvate kinase - Leishmania mexicana	169	7e-41
37	Q9Z984:KPYK_CHLPN Pyruvate kinase - Chlamydia pneumoniae (Chlamy...	108	1e-40
38	O62619:KPYK_DROME Pyruvate kinase - Drosophila melanogaster (Fru...	167	3e-40
39	P30616:KPYK2_TRYBB Pyruvate kinase 2 - Trypanosoma brucei brucei	162	5e-39
40	P30615:KPYK1_TRYBB Pyruvate kinase 1 - Trypanosoma brucei brucei	162	5e-39
41	P80885:KPYK_BACSU Pyruvate kinase - Bacillus subtilis	158	1e-37
42	P51182:KPYK_BACPY Pyruvate kinase - Bacillus psychrophilus (Spor...	158	1e-37
43	Q27788:KPYK_TRYBO Pyruvate kinase - Trypanoplasma borreli	155	1e-36
44	P51181:KPYK_BACLI Pyruvate kinase - Bacillus licheniformis	154	2e-36
45	Q02499:KPYK_BACST Pyruvate kinase - Bacillus stearothermophilus ...	151	2e-35
46	O08309:KPYK_CLOAB Pyruvate kinase - Clostridium acetobutylicum	149	6e-35
47	P0AD61:KPYK1_ECOLI Pyruvate kinase I - Escherichia coli	149	6e-35
48	P0AD62:KPYK1_ECO57 Pyruvate kinase I - Escherichia coli O157:H7	149	6e-35
49	P34038:KPYK_LACDE Pyruvate kinase - Lactobacillus delbrueckii su...	145	7e-34
50	Q49YC7:KPYK_STAS1 Pyruvate kinase - Staphylococcus saprophyticus...	144	2e-33
51	Q8CS69:KPYK_STAES Pyruvate kinase - Staphylococcus epidermidis (...	144	3e-33
52	Q5HNK7:KPYK_STAEQ Pyruvate kinase - Staphylococcus epidermidis (...	144	3e-33
53	Q6GG09:KPYK_STAAR Pyruvate kinase - Staphylococcus aureus (strai...	143	3e-33
54	Q7A0N4:KPYK_STAAW Pyruvate kinase - Staphylococcus aureus (strai...	142	1e-32
55	Q6G8M9:KPYK_STAAS Pyruvate kinase - Staphylococcus aureus (strai...	142	1e-32
56	Q7A559:KPYK_STAAN Pyruvate kinase - Staphylococcus aureus (strai...	142	1e-32
57	Q99TG5:KPYK_STAAM Pyruvate kinase - Staphylococcus aureus (strai...	142	1e-32
58	Q5HF76:KPYK_STAAC Pyruvate kinase - Staphylococcus aureus (strai...	142	1e-32
59	Q2YTE3:KPYK_STAAB Pyruvate kinase - Staphylococcus aureus (strai...	142	1e-32
60	Q2FXM9:KPYK_STAA8 Pyruvate kinase - Staphylococcus aureus (strai...	142	1e-32
61	Q2FG40:KPYK_STAA3 Pyruvate kinase - Staphylococcus aureus (strai...	142	1e-32
62	Q4L739:KPYK_STAHJ Pyruvate kinase - Staphylococcus haemolyticus ...	140	3e-32
63	Q46289:KPYK_CLOPE Pyruvate kinase - Clostridium perfringens	139	6e-32
64	O30853:KPYK1_PHOLE Pyruvate kinase I - Photobacterium leiognathi	133	4e-30
65	P70789:KPYK1_AGRVI Pyruvate kinase - Agrobacterium vitis (Rhizob...	132	6e-30
66	Q44473:KPYK2_AGRVI Pyruvate kinase - Agrobacterium vitis (Rhizob...	131	2e-29
67	Q07637:KPYK_LACLA Pyruvate kinase - Lactococcus lactis subsp. la...	127	3e-28
68	Q9PK61:KPYK_CHLMU Pyruvate kinase - Chlamydia muridarum	123	4e-27
69	Q9WY51:KPYK_THEMA Pyruvate kinase - Thermotoga maritima	121	1e-26
70	P73534:KPYK2_SYNY3 Pyruvate kinase 2 - Synechocystis sp. (strain...	121	2e-26
71	P94685:KPYK_CHLTR Pyruvate kinase - Chlamydia trachomatis	119	5e-26
72	Q55863:KPYK1_SYNY3 Pyruvate kinase 1 - Synechocystis sp. (strain...	116	4e-25
73	O06134:KPYK_MYCTU Pyruvate kinase - Mycobacterium tuberculosis	113	5e-24
74	O05118:KPYK_METEX Pyruvate kinase - Methylobacterium extorquens ...	112	6e-24
75	P94939:KPYK_MYCIT Pyruvate kinase - Mycobacterium intracellulare	110	2e-23
76	Q57572:KPYK_METJA Pyruvate kinase - Methanococcus jannaschii	109	7e-23
77	P32044:KPYK_THEAC Pyruvate kinase - Thermoplasma acidophilum	108	9e-23
78	Q46078:KPYK_CORGL Pyruvate kinase - Corynebacterium glutamicum (...	106	4e-22
79	Q89AI8:KPYK_BUCBP Pyruvate kinase - Buchnera aphidicola subsp. B...	106	4e-22
80	Q8FP04:KPYK_COREF Pyruvate kinase - Corynebacterium efficiens	106	6e-22
81	Q8ZNW0:KPYK2_SALTY Pyruvate kinase II - Salmonella typhimurium	105	8e-22
82	O51323:KPYK_BORBU Pyruvate kinase - Borrelia burgdorferi (Lyme d...	105	1e-21
83	P21599:KPYK2_ECOLI Pyruvate kinase II - Escherichia coli	104	2e-21
84	P43924:KPYK_HAEIN Pyruvate kinase - Haemophilus influenzae	103	3e-21
85	Q8K9M3:KPYK_BUCAP Pyruvate kinase - Buchnera aphidicola subsp. S...	102	6e-21
86	P57404:KPYK_BUCAI Pyruvate kinase - Buchnera aphidicola subsp. A...	100	3e-20
87	Q56301:KPYK_THELI Pyruvate kinase - Thermococcus litoralis	94	2e-18
88	Q43117:KPYA_RICCO Pyruvate kinase isozyme A, chloroplast precurs...	94	3e-18
89	Q40546:KPYG_TOBAC Pyruvate kinase isozyme G, chloroplast precurs...	93	7e-18
90	P55964:KPYG_RICCO Pyruvate kinase isozyme G, chloroplast - Ricin...	92	9e-18
91	P47458:KPYK_MYCGE Pyruvate kinase - Mycoplasma genitalium	90	6e-17
92	Q40545:KPYA_TOBAC Pyruvate kinase isozyme A, chloroplast precurs...	87	3e-16
93	P78031:KPYK_MYCPN Pyruvate kinase - Mycoplasma pneumoniae	84	3e-15
94	Q8ZYE0:KPYK_PYRAE Pyruvate kinase - Pyrobaculum aerophilum	80	6e-14
95	Q9YEU2:KPYK_AERPE Pyruvate kinase - Aeropyrum pernix	71	2e-11
96	Q04668:KPYK_LEIBR Pyruvate kinase - Leishmania braziliensis	65	1e-09
97	P19680:KPYK_SPICI Pyruvate kinase - Spiroplasma citri	47	3e-04
98	Q9ZKZ0:HLDE_HELPJ Bifunctional protein hldE [Includes: D-beta-D-...	35	1.3
99	Q1CT14:HLDE_HELPH Bifunctional protein hldE [Includes: D-beta-D-...	35	1.3
100	Q9BYP8:KR171_HUMAN Keratin-associated protein 17-1 - Homo sapien...	33	4.8
101	P25391:LAMA1_HUMAN Laminin subunit alpha-1 precursor - Homo sapi...	33	6.2
102	Q7SAX8:FIP1_NEUCR Pre-mRNA polyadenylation factor fip-1 - Neuros...	33	8.1
103	Q6P9Q4:FHOD1_MOUSE FH1/FH2 domain-containing protein 1 - Mus mus...	33	8.1
104	Q87UB2:AGUA_PSESM Agmatine deiminase - Pseudomonas syringae pv. ...	33	8.1

>Q42954:KPYC_TOBAC Pyruvate kinase, cytosolic isozyme - Nicotiana tabacum (Common|
            tobacco)
          Length = 508
 Score =  207 bits (528), Expect(2) = 4e-90
 Identities = 104/212 (49%), Positives = 147/212 (69%), Gaps = 1/212 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+ +FD+IL  +D  +++RG+LG+++P EK+FL QK  ++KCN+ GKP V  T++++SM
Sbjct: 243  EGVANFDDILLNSDAFMVARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESM 302

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              + RPTRAEATDVANAVLDG+D ++L  ET  G YP   + T+ +IC EAE   +    
Sbjct: 303  IKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPDLAVGTMAKICIEAESTIDYPDV 362

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            FKR +     PM+ LES+ASSAVR A   KA++I+  T  G  A+L+AKYRP MP+LSVV
Sbjct: 363  FKRIMSNAPVPMSPLESLASSAVRTANSAKAALILVLTRGGSTAKLVAKYRPGMPILSVV 422

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
            +P +KT+   W+ +    AR SLI RGL P+L
Sbjct: 423  VPEIKTDSFDWTCSDESPARHSLIFRGLVPVL 454



 Score =  147 bits (370), Expect(2) = 4e-90
 Identities = 87/238 (36%), Positives = 138/238 (57%), Gaps = 1/238 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP SRSV  I   L+AGM+VARF+FS G   YHQET++NL+ A+++T  LCAV
Sbjct: 20  TKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHDYHQETIDNLRQAMESTGILCAV 79

Query: 427 MLDTVGPELQV-VNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATI 603
           MLDT GPE++    K    + L++ + + ++     +    ++ +++  LA+ VKP + I
Sbjct: 80  MLDTKGPEIRTGFLKDAKPVQLKQGQEITISTDYSIKGDESMICMSYKKLAEDVKPQSVI 139

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
                L    + T   L   +  G D  C  +N+A L G    ++   + +D+PTL+D+D
Sbjct: 140 -----LCADGQITFTVLSCDKENGLD-RCRCENTAVL-GERKNVNLPGVIVDLPTLTDKD 192

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISRY 957
           KD +  WG PN ID ++LS+ R   D+ + R+ L +       L+ +K+EN E ++ +
Sbjct: 193 KDDILNWGVPNHIDMIALSFVRKGSDLVEVRKLLGE--HAKNILLMSKVENQEGVANF 248



 Score = 39.7 bits (91), Expect = 0.067
 Identities = 22/53 (41%), Positives = 29/53 (54%)
 Frame = +1

Query: 2269 HSFSALKAESTSTTNESVLKVALDHGKASGVIKSHDRVVVCQKVGDSSVVKII 2427
            H+ SA  +   ST  E  L  AL H K  G+ K  D VV   +VG +SV+KI+
Sbjct: 455  HAGSARASHEEST--EEALDFALQHAKTKGLCKQGDSVVALHRVGTASVIKIV 505

to top

>Q42806:KPYC_SOYBN Pyruvate kinase, cytosolic isozyme - Glycine max (Soybean)|
          Length = 511

 Score =  210 bits (534), Expect(2) = 5e-90
 Identities = 104/214 (48%), Positives = 146/214 (68%), Gaps = 1/214 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+ +FDEIL E D  +++RG+LG+++P EK+FL QK  ++KCN+ GKP V  T++++SM
Sbjct: 246  EGVLNFDEILRETDAFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESM 305

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              + RPTRAEATDVANAVLDG+D ++L  E+  G YP   +  + RIC EAE   +    
Sbjct: 306  IKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAVKIMARICIEAESSLDYGAI 365

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            FK  ++    PM+ LES+ASSAVR A K KA +I+  T  G  A+L+AKYRP +P+LSVV
Sbjct: 366  FKEMIRSTPLPMSPLESLASSAVRTANKAKAKLIVVLTRGGSTAKLVAKYRPAVPILSVV 425

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLAD 1717
            +P L T+   W+ +    AR SLI RGL P+L +
Sbjct: 426  VPVLSTDSFDWTCSDETPARHSLIYRGLIPILGE 459



 Score =  144 bits (363), Expect(2) = 5e-90
 Identities = 90/238 (37%), Positives = 133/238 (55%), Gaps = 1/238 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP SRSVE     L+AGM+VARF+FS G   YHQETL NLK A+  T  LCAV
Sbjct: 23  TKIVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLKTAMHNTGILCAV 82

Query: 427 MLDTVGPELQV-VNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATI 603
           MLDT GPE++    K    I L+E + V +T     +   +++ +++  L   +KPG TI
Sbjct: 83  MLDTKGPEIRTGFLKDGKPIQLKEGQEVTITTDYDIKGDPEMISMSYKKLPVHLKPGNTI 142

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
                      T ++ +   +     V C  +N+ATL G    ++   + +D+PTL+++D
Sbjct: 143 ------LCSDGTITLTVLSCDPDAGTVRCRCENTATL-GERKNVNLPGVVVDLPTLTEKD 195

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISRY 957
           K+ +  WG PNKID ++LS+ R   D+   R+ L       Q  + +K+EN E +  +
Sbjct: 196 KEDILGWGVPNKIDMIALSFVRKGSDLVNVRKVLGPHAKNIQ--LMSKVENQEGVLNF 251

to top

>P22200:KPYC_SOLTU Pyruvate kinase, cytosolic isozyme - Solanum tuberosum (Potato)|
          Length = 510

 Score =  208 bits (529), Expect(2) = 2e-89
 Identities = 102/214 (47%), Positives = 146/214 (68%), Gaps = 1/214 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+ +FDEIL E D  +++RG+LG+++P EK+FL QK  ++KCN+AGK  V  T++++SM
Sbjct: 245  EGVINFDEILRETDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLAGKAVVTATQMLESM 304

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              +  PTRAEATDVANAVLDG+D ++L  E+  G YP   +  + RIC EAE   + +  
Sbjct: 305  IKSPAPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAVKIMSRICIEAESSLDNEAI 364

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            FK  ++    PM+ LES+ASSAVR A K +A +I+  T  G  A+L+AKYRP +P+LSVV
Sbjct: 365  FKEMIRCTPLPMSPLESLASSAVRTANKARAKLIVVLTRGGSTAKLVAKYRPAVPILSVV 424

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLAD 1717
            +P L T+   WS +    AR SL+ RGL P+L +
Sbjct: 425  VPVLTTDSFDWSISDETPARHSLVYRGLIPLLGE 458



 Score =  144 bits (364), Expect(2) = 2e-89
 Identities = 89/238 (37%), Positives = 141/238 (59%), Gaps = 1/238 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP SR+V  +   L+AGM+VARF+FS G   YHQETL+NLKIA++ T+ LCAV
Sbjct: 22  TKIVCTLGPSSRTVPMLEKLLRAGMNVARFNFSHGTHEYHQETLDNLKIAMQNTQILCAV 81

Query: 427 MLDTVGPELQVVNKSE-VTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATI 603
           MLDT GPE++    ++   I L+E + + ++     + + +++ +++  L   +KPG TI
Sbjct: 82  MLDTKGPEIRTGFLTDGKPIQLKEGQEITVSTDYTIKGNEEMISMSYKKLVMDLKPGNTI 141

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
                   G+ T +V L      G  V C  +N+ATL G    ++   + +D+PTL+++D
Sbjct: 142 LCAD----GTITLTV-LSCDPPSG-TVRCRCENTATL-GERKNVNLPGVVVDLPTLTEKD 194

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISRY 957
           K+ + +WG PN ID ++LS+ R   D+   R+ L       Q  + +K+EN E +  +
Sbjct: 195 KEDILEWGVPNNIDMIALSFVRKGSDLVNVRKVLGPHAKRIQ--LMSKVENQEGVINF 250

to top

>O65595:KPYC_ARATH Probable pyruvate kinase, cytosolic isozyme - Arabidopsis thaliana|
            (Mouse-ear cress)
          Length = 497

 Score =  202 bits (514), Expect(2) = 6e-88
 Identities = 99/212 (46%), Positives = 146/212 (68%), Gaps = 1/212 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+ +FD+IL  +D  +++RG+LG+++P EK+FL QK  ++KCN  GKP V  T++++SM
Sbjct: 232  EGVANFDDILINSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNFMGKPVVTATQMLESM 291

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              + RPTRAEATDVANAVLDG+D ++L  ET  G YP   + T+ +IC EAE   +    
Sbjct: 292  IKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDI 351

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            FKR + +   PM+ +ES+ASSAVR A   +A++++  T  G  ARL+AKYRP +P+LSVV
Sbjct: 352  FKRIMLHAAVPMSPMESLASSAVRTATSSRATLMMVLTRGGSTARLVAKYRPGIPILSVV 411

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
            +P + ++   W+ +    AR SLI RGL P+L
Sbjct: 412  VPEITSDSFDWACSNEAPARHSLIYRGLVPVL 443



 Score =  145 bits (365), Expect(2) = 6e-88
 Identities = 87/238 (36%), Positives = 135/238 (56%), Gaps = 1/238 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP SRSV  +   L AGMSVARF+FS G   YHQETL+NL+ A+  T  LCAV
Sbjct: 9   TKIVCTLGPASRSVPMVEKLLMAGMSVARFNFSHGSYEYHQETLDNLRQAMLNTGMLCAV 68

Query: 427 MLDTVGPELQV-VNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATI 603
           MLDT GPE++    K    I L++ + + ++     +   K + +++  LA+ V PG  I
Sbjct: 69  MLDTKGPEIRTGFLKDGKPIQLKQGQEITISTDYDLKGDEKTICMSYKKLAQDVNPGMVI 128

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
                      T S+ +   + +   V C  +N++ L G    ++   + +D+PTL+++D
Sbjct: 129 ------LCADGTISLKVLSCDKEKGTVRCRCENTSML-GERKNVNLPGVVVDLPTLTEKD 181

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISRY 957
           K  + +WG PN+ID ++LS+ R   D+ Q R+ L K       L+ +K+EN E ++ +
Sbjct: 182 KQDILEWGVPNQIDMIALSFVRKGSDLVQVRKLLGK--HAKTILLMSKVENQEGVANF 237

to top

>Q12669:KPYK_ASPNG Pyruvate kinase - Aspergillus niger|
          Length = 526

 Score =  169 bits (427), Expect(2) = 8e-67
 Identities = 89/218 (40%), Positives = 131/218 (60%), Gaps = 1/218 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FDEILEE DG++++RG+LGI++P  KVF+ QK  + KCN+ GKP +  T++++SM
Sbjct: 259  QGVNNFDEILEETDGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPVICATQMLESM 318

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DVANAVLDG+D ++L  ET +G YP E +  +   C  AE        
Sbjct: 319  TYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGNYPNEAVKMMSETCLLAEVAIPHFNV 378

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F         P   +ESIA +AV A++++ A  I+  T+SG+ AR ++KYRP  P++ V 
Sbjct: 379  FDELRNLAPRPTDTVESIAMAAVSASLELNAGAIVVLTTSGKTARYLSKYRPVCPIVMVT 438

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHP 1729
                              +R S + RG++P L   + P
Sbjct: 439  -------------RNPAASRYSHLYRGVWPFLFPEKKP 463



 Score =  108 bits (269), Expect(2) = 8e-67
 Identities = 80/268 (29%), Positives = 137/268 (51%), Gaps = 4/268 (1%)
 Frame = +1

Query: 166 STNLLLEEPIRMVSILEPSKPNFFPAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFS 345
           S  + LE   ++ + + PSK NF    T I+GT+GPK+ SVE I++   AG++V R +FS
Sbjct: 11  SNRMKLEWHSKLNTEMVPSK-NF--RRTSIIGTIGPKTNSVEKINSLRTAGLNVVRMNFS 67

Query: 346 WGDAAYHQETLENLKIAIKA-TKKLCAVMLDTVGPELQVVN-KSEVTISLEENESVVLTP 519
            G   YHQ  ++N + A K    +  A+ LDT GPE++  N   +  I +++   + +T 
Sbjct: 68  HGSYQYHQSVIDNAREAAKTQVGRPLAIALDTKGPEIRTGNTPDDKDIPIKQGHELNITT 127

Query: 520 HKGQEASS--KLLPINFSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCV 693
            +    +S  K + +++  + K + PG  I+V   + +         EV EV  D  + V
Sbjct: 128 DEQYATASDDKNMYLDYKNITKVISPGKLIYVDDGILS--------FEVLEVVDDKTIRV 179

Query: 694 IKNSATLAGSLFTLHCSQIHIDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQA 873
              +     S   ++     +D+P LS++D   + K+G  NK+D +  S+ R   D+R  
Sbjct: 180 RCLNNGNISSRKGVNLPGTDVDLPALSEKDIADL-KFGVRNKVDMVFASFIRRGSDIRHI 238

Query: 874 REFLSKLGDLSQTLIFAKIENVEVISRY 957
           RE L + G   +  I AKIEN + ++ +
Sbjct: 239 REVLGEEG--KEIQIIAKIENQQGVNNF 264

to top

>P11980:KPYM_RAT Pyruvate kinase isozymes M1/M2 - Rattus norvegicus (Rat)|
          Length = 531

 Score =  165 bits (417), Expect(2) = 1e-64
 Identities = 89/212 (41%), Positives = 130/212 (61%), Gaps = 1/212 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN AGKP +  T++++SM
Sbjct: 275  EGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESM 334

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
                RPTRAE +DVANAVLDG+D I+L  ET +G YP+E +     I  EAE      L 
Sbjct: 335  IKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAVFHRLL 394

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F+   +   +    LE++A  +V A+ K  A+ +I  T SGR+A  +A+YRP  P+++V 
Sbjct: 395  FEELARASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT 454

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
                              ARQ+ + RG+FP+L
Sbjct: 455  -------------RNPQTARQAHLYRGIFPVL 473



 Score =  104 bits (260), Expect(2) = 1e-64
 Identities = 73/248 (29%), Positives = 130/248 (52%), Gaps = 11/248 (4%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA------T 408
           T I+ T+GP SRSVE +   +K+GM+VAR +FS G   YH ET++N++ A ++       
Sbjct: 45  TGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPIL 104

Query: 409 KKLCAVMLDTVGPELQ---VVNKSEVTISLEENESVVLTPHKG--QEASSKLLPINFSGL 573
            +  AV LDT GPE++   +       + L++  ++ +T      ++    +L +++  +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164

Query: 574 AKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIH 753
            K V+ G+ I+V   L +        L+V E   D +V  ++N  +L GS   ++     
Sbjct: 165 CKVVEVGSKIYVDDGLIS--------LQVKEKGADYLVTEVENGGSL-GSKKGVNLPGAA 215

Query: 754 IDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIE 933
           +D+P +S++D   + K+G    +D +  S+ R A DV + R+ L + G      I +KIE
Sbjct: 216 VDLPAVSEKDIQDL-KFGVEQDVDMVFASFIRKAADVHEVRKVLGEKG--KNIKIISKIE 272

Query: 934 NVEVISRY 957
           N E + R+
Sbjct: 273 NHEGVRRF 280

to top

>Q8Z6K2:KPYK1_SALTI Pyruvate kinase I - Salmonella typhi|
          Length = 470

 Score =  150 bits (379), Expect(2) = 2e-64
 Identities = 77/189 (40%), Positives = 118/189 (62%), Gaps = 1/189 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +GLN+FDEILE +DGI+++RG+LG+++P E+V   QK  + KC  A K  +  T+++DSM
Sbjct: 225  EGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSM 284

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N RPTRAEA DVANA+LDG+DA++L  E+ +G YP+E +S +  IC   ++V N  L 
Sbjct: 285  IKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLD 344

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            +          +   E++   AV  A K+KA +I+  T  G++AR + KY P   +L++ 
Sbjct: 345  YNND----SRKLRITEAVCRGAVETAEKLKAPLIVVATQGGKSARAVRKYFPDATILALT 400

Query: 1616 IPRLKTNQL 1642
               +   QL
Sbjct: 401  TNEVTARQL 409



 Score =  119 bits (297), Expect(2) = 2e-64
 Identities = 73/238 (30%), Positives = 129/238 (54%), Gaps = 1/238 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GPK+ S E +S  L AGM+V R +FS GD A H + ++NL+  +  T K  A+
Sbjct: 4   TKIVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKKAAI 63

Query: 427 MLDTVGPELQVVN-KSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATI 603
           +LDT GPE++ +  +    +SL+  ++   T  K    +++++ + + G    +  G T+
Sbjct: 64  LLDTKGPEIRTIKLEGGNDVSLKAGQTFTFTTDKSVVGNNEIVAVTYEGFTSDLSVGNTV 123

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
            V   L        + +EV+ ++G+ V+C + N+  L G    ++   + I +P L+++D
Sbjct: 124 LVDDGL--------IGMEVTAIEGNKVICKVLNNGDL-GENKGVNLPGVSIALPALAEKD 174

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISRY 957
           K  +  +G    +DF++ S+ R   DV + RE L   G      I +KIEN E ++ +
Sbjct: 175 KQDL-IFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGG-ENIQIISKIENQEGLNNF 230

to top

>P77983:KPYK1_SALTY Pyruvate kinase I - Salmonella typhimurium|
          Length = 470

 Score =  149 bits (375), Expect(2) = 5e-64
 Identities = 76/189 (40%), Positives = 118/189 (62%), Gaps = 1/189 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +GLN+FDEILE +DGI+++RG+LG+++P E+V   QK  + KC  A K  +  T+++DSM
Sbjct: 225  EGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSM 284

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N RPTRAEA DVANA+LDG+DA++L  E+ +G YP+E +S +  IC   ++V N  L 
Sbjct: 285  IKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLD 344

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            +          +   E++   AV  A K++A +I+  T  G++AR + KY P   +L++ 
Sbjct: 345  YNND----SRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILALT 400

Query: 1616 IPRLKTNQL 1642
               +   QL
Sbjct: 401  TNEVTARQL 409



 Score =  119 bits (297), Expect(2) = 5e-64
 Identities = 73/238 (30%), Positives = 129/238 (54%), Gaps = 1/238 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GPK+ S E +S  L AGM+V R +FS GD A H + ++NL+  +  T K  A+
Sbjct: 4   TKIVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKKAAI 63

Query: 427 MLDTVGPELQVVN-KSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATI 603
           +LDT GPE++ +  +    +SL+  ++   T  K    +++++ + + G    +  G T+
Sbjct: 64  LLDTKGPEIRTIKLEGGNDVSLKAGQTFTFTTDKSVVGNNEIVAVTYEGFTSDLSVGNTV 123

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
            V   L        + +EV+ ++G+ V+C + N+  L G    ++   + I +P L+++D
Sbjct: 124 LVDDGL--------IGMEVTAIEGNKVICKVLNNGDL-GENKGVNLPGVSIALPALAEKD 174

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISRY 957
           K  +  +G    +DF++ S+ R   DV + RE L   G      I +KIEN E ++ +
Sbjct: 175 KQDL-IFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGG-ENIQIISKIENQEGLNNF 230

to top

>P22360:KPYK_EMENI Pyruvate kinase - Emericella nidulans (Aspergillus nidulans)|
          Length = 526

 Score =  169 bits (428), Expect(2) = 6e-64
 Identities = 83/179 (46%), Positives = 120/179 (67%), Gaps = 1/179 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FDEILEE DG++++RG+LGI++P  KVF+ QK  + KCN+ GKP +  T++++SM
Sbjct: 259  QGVNNFDEILEETDGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPVICATQMLESM 318

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DVANAVLDG+D ++L  ET +G YP E ++ +   C  AE        
Sbjct: 319  TYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGNYPCEAVTMMSETCLLAEVAIPHFNV 378

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            F         P   +ESIA +AV A++++ A  I+  T+SG  AR+I+KYRP  P++ V
Sbjct: 379  FDELRNLAPRPTDTVESIAMAAVSASLELNAGAIVVLTTSGNTARMISKYRPVCPIIMV 437



 Score = 98.2 bits (243), Expect(2) = 6e-64
 Identities = 74/268 (27%), Positives = 131/268 (48%), Gaps = 4/268 (1%)
 Frame = +1

Query: 166 STNLLLEEPIRMVSILEPSKPNFFPAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFS 345
           S  + LE   ++ + + P+K NF    T I+ T+GPK+ SVE I+A  +AG++V R +FS
Sbjct: 11  SNRMKLEWHSKLNTEMVPAK-NF--RRTSIICTIGPKTNSVEKINALRRAGLNVVRMNFS 67

Query: 346 WGDAAYHQETLENLKIAIK-ATKKLCAVMLDTVGPELQ---VVNKSEVTISLEENESVVL 513
            G   YHQ  +++ + A K    +  A+ LDT GPE++    V   ++ I      ++  
Sbjct: 68  HGSYEYHQSVIDHAREAEKQQAGRPVAIALDTKGPEIRTGNTVGDKDIPIKAGHEMNIST 127

Query: 514 TPHKGQEASSKLLPINFSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCV 693
                  +  + + +++  + K +  G  I+V   + +         EV EV  D  + V
Sbjct: 128 DEQYATASDDQNMYVDYKNITKVISAGKLIYVDDGILS--------FEVLEVVDDKTLRV 179

Query: 694 IKNSATLAGSLFTLHCSQIHIDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQA 873
              +     S   ++     +D+P LS++D   + K+G  NK+D +  S+ R   D+R  
Sbjct: 180 RCLNNGNISSRKGVNLPGTDVDLPALSEKDISDL-KFGVKNKVDMVFASFIRRGSDIRHI 238

Query: 874 REFLSKLGDLSQTLIFAKIENVEVISRY 957
           RE L + G   +  I AKIEN + ++ +
Sbjct: 239 REVLGEEG--REIQIIAKIENQQGVNNF 264

to top

>Q92122:KPYK_XENLA Pyruvate kinase muscle isozyme - Xenopus laevis (African clawed frog)|
          Length = 527

 Score =  162 bits (411), Expect(2) = 1e-63
 Identities = 92/215 (42%), Positives = 133/215 (61%), Gaps = 4/215 (1%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN AGKP +  T++++SM
Sbjct: 271  EGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESM 330

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAE-KVFNQDL 1432
                RPTRAE +DVANAVLDG+D I+L  ET +G YP+E +     I  EAE  +F++ L
Sbjct: 331  IKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAIFHRQL 390

Query: 1433 Y--FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVL 1606
            +   +R      +P    E+ A  AV A+ K  +  II  T SGR+A L+++YRP  P++
Sbjct: 391  FEELRRVSPLTRDP---TEATAVGAVEASFKCSSGAIIVLTKSGRSAHLLSRYRPRAPII 447

Query: 1607 SVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
            SV                   ARQ+ + RG+FP+L
Sbjct: 448  SVT-------------RNGQTARQAHLYRGIFPVL 469



 Score =  103 bits (257), Expect(2) = 1e-63
 Identities = 76/248 (30%), Positives = 123/248 (49%), Gaps = 11/248 (4%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATK----- 411
           T I+ T+GP SRSVE +   +K+GM++AR +FS G   YH  T++N++ A ++       
Sbjct: 41  TGIICTIGPASRSVEMLKEMIKSGMNIARLNFSHGTHEYHAGTIKNVREATESLASNPIH 100

Query: 412 -KLCAVMLDTVGPELQV-----VNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGL 573
            +  AV LDT GPE++         +EV +       + L     +     +L +++  L
Sbjct: 101 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATMRITLDDAFQENCDENVLWVDYKNL 160

Query: 574 AKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIH 753
            K VKPG+ I+V   L +        L V E+  D  V  I+N   L GS   ++     
Sbjct: 161 TKVVKPGSKIYVDDGLIS--------LLVKEIGPDFCVTEIENGGML-GSKKGVNLPGAA 211

Query: 754 IDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIE 933
           +D+P +S +D   + ++G    +D +  S+ R A DV + RE L + G      I +KIE
Sbjct: 212 VDLPAVSSKDIQDL-QFGVEQDVDMVFASFIRKAADVHEVREVLGEKG--KNIKIISKIE 268

Query: 934 NVEVISRY 957
           N E + R+
Sbjct: 269 NHEGVRRF 276

to top

>P11979:KPYM_FELCA Pyruvate kinase isozyme M1 - Felis silvestris catus (Cat)|
          Length = 531

 Score =  162 bits (410), Expect(2) = 2e-63
 Identities = 90/216 (41%), Positives = 134/216 (62%), Gaps = 2/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN AGKP +  T++++SM
Sbjct: 275  EGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESM 334

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
                RPTRAE +DVANAVLDG+D I+L  ET +G YP+E +     I  EAE        
Sbjct: 335  IKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKL 394

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F+  V+        +E++A  +V A+ K  A+ +I  T SGR+A  +A+YRP  P+++V 
Sbjct: 395  FEELVRGSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT 454

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLA-DP 1720
                + +Q          ARQ+ + RG+FP++  DP
Sbjct: 455  ----RNHQ---------TARQAHLYRGIFPVVCKDP 477



 Score =  103 bits (256), Expect(2) = 2e-63
 Identities = 74/260 (28%), Positives = 132/260 (50%), Gaps = 11/260 (4%)
 Frame = +1

Query: 211 LEPSKPNFFPAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLK 390
           L+   P      T I+ T+GP SRSVE +   +K+GM+VAR +FS G   YH ET++N++
Sbjct: 33  LDIDSPPITARNTGIICTIGPASRSVEILKEMIKSGMNVARLNFSHGTHEYHAETIKNVR 92

Query: 391 IAIKA------TKKLCAVMLDTVGPELQ---VVNKSEVTISLEENESVVLTPHKG--QEA 537
            A ++        +  AV LDT GPE++   +       + L++  ++ +T      ++ 
Sbjct: 93  AATESFASDPIRYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKC 152

Query: 538 SSKLLPINFSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLA 717
              +L +++  + K V+ G+ ++V   L +        L V E   D +V  ++N  +L 
Sbjct: 153 DENVLWLDYKNICKVVEVGSKVYVDDGLIS--------LLVKEKGADFLVTEVENGGSL- 203

Query: 718 GSLFTLHCSQIHIDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLG 897
           GS   ++     +D+P +S++D   + K+G    +D +  S+ R A DV + R+ L + G
Sbjct: 204 GSKKGVNLPGAAVDLPAVSEKDIQDL-KFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262

Query: 898 DLSQTLIFAKIENVEVISRY 957
                 I +KIEN E + R+
Sbjct: 263 --KNIKIISKIENHEGVRRF 280

to top

>P31865:KPYK_TRIRE Pyruvate kinase - Trichoderma reesei (Hypocrea jecorina)|
          Length = 538

 Score =  160 bits (404), Expect(2) = 4e-63
 Identities = 87/218 (39%), Positives = 131/218 (60%), Gaps = 1/218 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QGLN+F EILEE DG++++RG+LGI++P  +VF  QK  +  CN+AGKP +  T++++SM
Sbjct: 268  QGLNNFAEILEETDGVMVARGDLGIEIPAAEVFAAQKKMIAMCNIAGKPVICATQMLESM 327

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N RPTRAE +DV NAV DG+D ++L  ET +G YP E+I  +     +AE       +
Sbjct: 328  IKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGNYPAESIHEMHEASLKAENTIPYVSH 387

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F+     V  P++ +ES A +AVRA++ + A  II  ++SG +ARL++KYRP  P+  V 
Sbjct: 388  FEEMCTLVKRPVSTVESCAMAAVRASLDLGAGGIIVLSTSGDSARLLSKYRPVCPIFMVT 447

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHP 1729
                              +R S + RG++P L   + P
Sbjct: 448  -------------RNPTTSRFSHLYRGVYPFLYPEQKP 472



 Score =  104 bits (260), Expect(2) = 4e-63
 Identities = 66/242 (27%), Positives = 124/242 (51%), Gaps = 4/242 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA-TKKLCA 423
           T I+ T+GPK+ SVEA++    AG++VAR +FS G   YHQ  ++N++ ++ A   +  A
Sbjct: 44  TSIICTIGPKTNSVEALNKLRDAGLNVARMNFSHGSYEYHQSVIDNVRASVAAHPGRPVA 103

Query: 424 VMLDTVGPELQVVNKS---EVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++  N +   ++ IS     +            ++ + +++  + K ++PG
Sbjct: 104 IALDTKGPEIRTGNTAGDVDIPISAGTVMNFTTDEKYATACDTQNMYVDYKNITKVIQPG 163

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             I+V   +           +V  ++ D  V V   +     S   ++     +D+P LS
Sbjct: 164 RVIYVDDGVLA--------FDVLSIKDDQTVEVRARNNGFISSRKGVNLPNTDVDLPALS 215

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           ++DK  + ++G  N +D +  S+ R A+D++  R+ L   G   Q  I AKIEN + ++ 
Sbjct: 216 EKDKADL-RFGVKNNVDMVFASFIRRAQDIKDIRDVLGPEG--KQIQIIAKIENRQGLNN 272

Query: 955 YS 960
           ++
Sbjct: 273 FA 274

to top

>O94122:KPYK_AGABI Pyruvate kinase - Agaricus bisporus (Common mushroom)|
          Length = 532

 Score =  162 bits (409), Expect(2) = 4e-63
 Identities = 80/179 (44%), Positives = 121/179 (67%), Gaps = 1/179 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            QG+ +FDEIL+EADG++++RG+LGI++P  +VFL QK  + KCN+ GKP +V T++++SM
Sbjct: 259  QGVANFDEILKEADGVMVARGDLGIEIPASQVFLAQKMMIAKCNIVGKPVIVATQMLESM 318

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DVANAVLDGSD ++L  ET +G YPV+++  +   C  AE        
Sbjct: 319  TYNPRPTRAEVSDVANAVLDGSDCVMLSGETAKGSYPVQSVLMMAETCLLAETAICYPPL 378

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            +         P    E++A +AV AA +  A  ++  ++SG  ARL++KYRP +P+++V
Sbjct: 379  YDDLRAVQARPTETAETVAIAAVAAAAEQDAKALLVLSTSGETARLVSKYRPKIPIITV 437



 Score =  102 bits (255), Expect(2) = 4e-63
 Identities = 71/252 (28%), Positives = 127/252 (50%), Gaps = 5/252 (1%)
 Frame = +1

Query: 217 PSKPNFFPAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIA 396
           P++   +   T I+ T+GPK  +VE ++    AG+++ R +FS G   YHQ  ++N +  
Sbjct: 25  PTETTKYHRKTAIIATIGPKINTVEKLTDVRLAGVNIVRMNFSHGTHEYHQSVIDNTRQM 84

Query: 397 IKATK--KLCAVMLDTVGPEL---QVVNKSEVTISLEENESVVLTPHKGQEASSKLLPIN 561
           IK     +  A+ LDT GPE+   Q  + ++  I   +   V   P       +K+L ++
Sbjct: 85  IKNDPHGRPVAIALDTKGPEIRTGQTRDGNDYPIKAGDEFIVTTDPKYSDICDNKVLFVD 144

Query: 562 FSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHC 741
           ++ LA    PG  I++   + +        L +  + G ++     N+ TL+ S   ++ 
Sbjct: 145 YANLASVTAPGKLIYIDDGIIS--------LLILSIDGMNLHVRALNNGTLS-SRKGVNL 195

Query: 742 SQIHIDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIF 921
            +  +D+P LS++DKD + ++G  N +D +  S+ R  EDVRQ RE L    D +   I 
Sbjct: 196 PKTDVDLPPLSEKDKDDL-RFGIRNGVDMIFASFIRRGEDVRQIREVLGP--DGASIKII 252

Query: 922 AKIENVEVISRY 957
            KIEN + ++ +
Sbjct: 253 VKIENEQGVANF 264

to top

>Q5NVN0:KPYM_PONPY Pyruvate kinase isozyme M1 - Pongo pygmaeus (Orangutan)|
          Length = 531

 Score =  160 bits (405), Expect(2) = 5e-63
 Identities = 89/216 (41%), Positives = 130/216 (60%), Gaps = 2/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN AGKP +  T++++SM
Sbjct: 275  EGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESM 334

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
                RPTRAE + VANAVLDG+D I+L  ET +G YP+E +     I  EAE        
Sbjct: 335  IKKPRPTRAEGSGVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKL 394

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F+  V+        +E++A  +V A+ K  A+ +I  T SGR+A  +A+YRP  P+++V 
Sbjct: 395  FEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT 454

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLA-DP 1720
                              ARQ+ + RG+FP+L  DP
Sbjct: 455  -------------RNPQTARQAHLYRGIFPVLCKDP 477



 Score =  103 bits (258), Expect(2) = 5e-63
 Identities = 73/260 (28%), Positives = 133/260 (51%), Gaps = 11/260 (4%)
 Frame = +1

Query: 211 LEPSKPNFFPAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLK 390
           L+   P      T I+ T+GP SRSVE +   +K+GM+VAR +FS G   YH ET++N++
Sbjct: 33  LDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVR 92

Query: 391 IAIKA------TKKLCAVMLDTVGPELQ---VVNKSEVTISLEENESVVLTPHKG--QEA 537
            A ++        +  AV LDT GPE++   +       + L++  ++ +T      ++ 
Sbjct: 93  TATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKC 152

Query: 538 SSKLLPINFSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLA 717
              +L +++  + K V+ G+ I+V   L +        L+V +   D ++  ++N  +L 
Sbjct: 153 DENILWLDYKNICKVVEVGSKIYVDDGLIS--------LQVKQKGADFLLTEVENGGSL- 203

Query: 718 GSLFTLHCSQIHIDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLG 897
           GS   ++     +D+P +S++D   + K+G    +D +  S+ R A DV + R+ L + G
Sbjct: 204 GSKKGVNLPGAAVDLPAVSEKDIQDL-KFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262

Query: 898 DLSQTLIFAKIENVEVISRY 957
                 I +KIEN E + R+
Sbjct: 263 --KNIKIISKIENHEGVRRF 280

to top

>P14618:KPYM_HUMAN Pyruvate kinase isozymes M1/M2 - Homo sapiens (Human)|
          Length = 531

 Score =  158 bits (399), Expect(2) = 1e-62
 Identities = 92/219 (42%), Positives = 133/219 (60%), Gaps = 5/219 (2%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN AGKP +  T++++SM
Sbjct: 275  EGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESM 334

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAE-KVFNQDL 1432
                RPTRAE +DVANAVLDG+D I+L  ET +G YP+E +     I  EAE  +++  L
Sbjct: 335  IKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQL 394

Query: 1433 Y--FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVL 1606
            +   +R      +P    E+ A  AV A+ K  +  II  T SGR+A  +A+YRP  P++
Sbjct: 395  FEELRRLAPITSDP---TEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPII 451

Query: 1607 SVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLA-DP 1720
            +V                   ARQ+ + RG+FP+L  DP
Sbjct: 452  AVT-------------RNPQTARQAHLYRGIFPVLCKDP 477



 Score =  105 bits (261), Expect(2) = 1e-62
 Identities = 74/260 (28%), Positives = 133/260 (51%), Gaps = 11/260 (4%)
 Frame = +1

Query: 211 LEPSKPNFFPAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLK 390
           L+   P      T I+ T+GP SRSVE +   +K+GM+VAR +FS G   YH ET++N++
Sbjct: 33  LDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVR 92

Query: 391 IAIKA------TKKLCAVMLDTVGPELQ---VVNKSEVTISLEENESVVLTPHKG--QEA 537
            A ++        +  AV LDT GPE++   +       + L++  ++ +T      ++ 
Sbjct: 93  TATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKC 152

Query: 538 SSKLLPINFSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLA 717
              +L +++  + K V+ G+ I+V   L +        L+V +   D +V  ++N  +L 
Sbjct: 153 DENILWLDYKNICKVVEVGSKIYVDDGLIS--------LQVKQKGADFLVTEVENGGSL- 203

Query: 718 GSLFTLHCSQIHIDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLG 897
           GS   ++     +D+P +S++D   + K+G    +D +  S+ R A DV + R+ L + G
Sbjct: 204 GSKKGVNLPGAAVDLPAVSEKDIQDL-KFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG 262

Query: 898 DLSQTLIFAKIENVEVISRY 957
                 I +KIEN E + R+
Sbjct: 263 --KNIKIISKIENHEGVRRF 280

to top

>Q7RVA8:KPYK_NEUCR Pyruvate kinase - Neurospora crassa|
          Length = 527

 Score =  157 bits (398), Expect(2) = 1e-62
 Identities = 81/218 (37%), Positives = 129/218 (59%), Gaps = 1/218 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QGLN+F EIL E DG++++RG+LGI++P  +VF  QK  +  CN+AGKP +  T++++SM
Sbjct: 258  QGLNNFAEILAETDGVMVARGDLGIEIPAAEVFAAQKKIIAMCNIAGKPVICATQMLESM 317

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N RPTRAE +DV NAV DG+D ++L  ET +G YP E +  +     +AE       +
Sbjct: 318  IKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGAYPTEAVREMSEAVLKAENTIPYVSH 377

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F+        P++ +ES A ++VRA++ + A+ I+  ++SG +ARLI+KYRP  P++ + 
Sbjct: 378  FEELCSLAKRPVSIVESCAMASVRASLDLNAAAILVLSTSGESARLISKYRPVCPIIMIT 437

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHP 1729
                              +R + + RG++P L     P
Sbjct: 438  -------------RNDSASRYAHLYRGVYPFLFPESKP 462



 Score =  105 bits (262), Expect(2) = 1e-62
 Identities = 70/242 (28%), Positives = 122/242 (50%), Gaps = 4/242 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA-TKKLCA 423
           T I+ T+GPK+ SVEAI+    AG++V R +FS G   YHQ  ++N + A K    +  A
Sbjct: 34  TSIICTIGPKTNSVEAINKLRDAGLNVVRMNFSHGSYEYHQSVIDNARQAEKVHPGRPIA 93

Query: 424 VMLDTVGPELQ---VVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++     N  ++ IS     ++        E + + + +++  + K + PG
Sbjct: 94  IALDTKGPEIRTGNTKNDEDIPISAGTILNITTDEKYKDECTIEHMYVDYVNITKVIAPG 153

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             I+V   +           EV E+  D  + V   +     S   ++     +D+P LS
Sbjct: 154 RIIYVDDGVLA--------FEVLEIVDDKTIKVKARNNGYISSRKGVNLPNTDVDLPALS 205

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           ++DK  + ++G  NK+D +  S+ R  +D++  RE L +  D  Q  I AKIEN + ++ 
Sbjct: 206 EKDKADL-RFGVKNKVDMVFASFIRRGQDIKDIREVLGE--DGKQIQIIAKIENRQGLNN 262

Query: 955 YS 960
           ++
Sbjct: 263 FA 264

to top

>P30614:KPYK_YARLI Pyruvate kinase - Yarrowia lipolytica (Candida lipolytica)|
          Length = 515

 Score =  172 bits (435), Expect(2) = 1e-62
 Identities = 91/212 (42%), Positives = 132/212 (62%), Gaps = 1/212 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FDEIL+E DG++++RG+LGI++P  +VF+ QK  + KCN+AGKP +  T+++DSM
Sbjct: 256  QGVNNFDEILKETDGVMVARGDLGIEIPAPQVFIAQKQLIAKCNLAGKPVICATQMLDSM 315

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NAVLDG+D ++L  ET +G YP+E++  +   C  AEK       
Sbjct: 316  TYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGTYPIESVKMMHETCLVAEKAIAYAPL 375

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F         P   +E+IA SAV A+ + +A  II  ++SG +ARL +KYRP  P+L V 
Sbjct: 376  FNEMRTLTVRPTETVETIAISAVSASFEQQARAIIVLSTSGTSARLCSKYRPNCPILMVT 435

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
                           A  AR S + RG++P +
Sbjct: 436  -------------RNAQAARFSHLYRGVYPFI 454



 Score = 91.3 bits (225), Expect(2) = 1e-62
 Identities = 62/241 (25%), Positives = 126/241 (52%), Gaps = 4/241 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATK-KLCA 423
           + I+GT+GP + S E IS   +AG+++ R +FS G   YHQ  +EN + + +  + +  A
Sbjct: 32  SSIIGTIGPNTNSAEMISKLRQAGLNIVRMNFSHGSYEYHQSVIENARESEQQFQGRPLA 91

Query: 424 VMLDTVGPELQV-VNKSEVTISLEENESVVLT--PHKGQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++  V K +    ++    ++ +  P    +   K++ I+++ + K +  G
Sbjct: 92  IALDTKGPEIRTGVTKDDKDWDVKAGHVMLFSTNPKYKDQCDDKIMYIDYTNIVKQIDIG 151

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             IFV   + +       +  + ++ G+ +     N+  ++ S   ++     +D+P LS
Sbjct: 152 KIIFVDDGVLS-------FKVLEKIDGETLKVETLNNGKIS-SRKGVNLPGTDVDLPALS 203

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           ++DK  + K+G  + +D +  S+ R A DV+  R+ L + G   Q  + +KIEN + ++ 
Sbjct: 204 EKDKADL-KFGVEHGVDMIFASFVRTANDVQAIRDVLGEKGKGIQ--VISKIENQQGVNN 260

Query: 955 Y 957
           +
Sbjct: 261 F 261

to top

>P11974:KPYM_RABIT Pyruvate kinase isozymes M1/M2 - Oryctolagus cuniculus (Rabbit)|
          Length = 531

 Score =  161 bits (407), Expect(2) = 2e-62
 Identities = 89/216 (41%), Positives = 133/216 (61%), Gaps = 2/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN AGKP +  T++++SM
Sbjct: 275  EGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESM 334

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
                RPTRAE +DVANAVLDG+D I+L  ET +G YP+E +     I  EAE        
Sbjct: 335  IKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKL 394

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F+   +        +E++A  +V A+ K  A+ +I  T SGR+A  +A+YRP  P+++V 
Sbjct: 395  FEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT 454

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLA-DP 1720
                + +Q          ARQ+ + RG+FP++  DP
Sbjct: 455  ----RNHQ---------TARQAHLYRGIFPVVCKDP 477



 Score =  101 bits (251), Expect(2) = 2e-62
 Identities = 71/248 (28%), Positives = 128/248 (51%), Gaps = 11/248 (4%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA------T 408
           T I+ T+GP SRSVE +   +K+GM+VAR +FS G   YH ET++N++ A ++       
Sbjct: 45  TGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPIL 104

Query: 409 KKLCAVMLDTVGPELQ---VVNKSEVTISLEENESVVLTPHKG--QEASSKLLPINFSGL 573
            +  AV LDT GPE++   +       + L++  ++ +T      ++    +L +++  +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164

Query: 574 AKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIH 753
            K V  G+ ++V   L +        L+V +   D +V  ++N   L GS   ++     
Sbjct: 165 CKVVDVGSKVYVDDGLIS--------LQVKQKGPDFLVTEVENGGFL-GSKKGVNLPGAA 215

Query: 754 IDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIE 933
           +D+P +S++D   + K+G    +D +  S+ R A DV + R+ L + G      I +KIE
Sbjct: 216 VDLPAVSEKDIQDL-KFGVEQDVDMVFASFIRKAADVHEVRKILGEKG--KNIKIISKIE 272

Query: 934 NVEVISRY 957
           N E + R+
Sbjct: 273 NHEGVRRF 280

to top

>P52480:KPYM_MOUSE Pyruvate kinase isozymes M1/M2 - Mus musculus (Mouse)|
          Length = 531

 Score =  157 bits (398), Expect(2) = 3e-62
 Identities = 90/215 (41%), Positives = 131/215 (60%), Gaps = 4/215 (1%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN AGKP +  T++++SM
Sbjct: 275  EGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESM 334

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAE-KVFNQDL 1432
                RPTRAE +DVANAVLDG+D I+L  ET +G YP+E +     I  EAE  +++  L
Sbjct: 335  IKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQL 394

Query: 1433 Y--FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVL 1606
            +   +R      +P    E+ A  AV A+ K  +  II  T SGR+A  +A+YRP  P++
Sbjct: 395  FEELRRLAPITSDP---TEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPII 451

Query: 1607 SVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
            +V                   ARQ+ + RG+FP+L
Sbjct: 452  AVT-------------RNPQTARQAHLYRGIFPVL 473



 Score =  103 bits (258), Expect(2) = 3e-62
 Identities = 73/248 (29%), Positives = 130/248 (52%), Gaps = 11/248 (4%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA------T 408
           T I+ T+GP SRSVE +   +K+GM+VAR +FS G   YH ET++N++ A ++       
Sbjct: 45  TGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFASDPIL 104

Query: 409 KKLCAVMLDTVGPELQ---VVNKSEVTISLEENESVVLTPHKG--QEASSKLLPINFSGL 573
            +  AV LDT GPE++   +       + L++  ++ +T      ++    +L +++  +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164

Query: 574 AKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIH 753
            K V+ G+ I+V   L +        L+V E   D +V  ++N  +L GS   ++     
Sbjct: 165 CKVVEVGSKIYVDDGLIS--------LQVKEKGADFLVTEVENGGSL-GSKKGVNLPGAA 215

Query: 754 IDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIE 933
           +D+P +S++D   + K+G    +D +  S+ R A DV + R+ L + G      I +KIE
Sbjct: 216 VDLPAVSEKDIQDL-KFGVEQDVDMVFASFIRKAADVHEVRKVLGEKG--KNIKIISKIE 272

Query: 934 NVEVISRY 957
           N E + R+
Sbjct: 273 NHEGVRRF 280

to top

>P00548:KPYK_CHICK Pyruvate kinase muscle isozyme - Gallus gallus (Chicken)|
          Length = 530

 Score =  163 bits (413), Expect(2) = 6e-62
 Identities = 89/218 (40%), Positives = 136/218 (62%), Gaps = 2/218 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEI+E +DGI+++RG+LGI++P EKVFL QK  + +CN AGKP +  T++++SM
Sbjct: 274  EGVRRFDEIMEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPIICATQMLESM 333

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
                RPTRAE +DVANAVLDG+D I+L  ET +G YP+E +     I  EAE        
Sbjct: 334  IKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAMFHRQQ 393

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F+  +++        +++A+ AV A+ K  A+ +I  T SGR+A L+++YRP  P+++V 
Sbjct: 394  FEEILRHSVHHREPADAMAAGAVEASFKCLAAALIVMTESGRSAHLVSRYRPRAPIIAVT 453

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLA-DPRH 1726
                + +Q          ARQ+ + RG+FP+L   P H
Sbjct: 454  ----RNDQ---------TARQAHLYRGVFPVLCKQPAH 478



 Score = 97.4 bits (241), Expect(2) = 6e-62
 Identities = 71/248 (28%), Positives = 126/248 (50%), Gaps = 11/248 (4%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA------T 408
           T I+ T+GP SRSV+ +   +K+GM+VAR +FS G   YH+ T++N++ A ++      T
Sbjct: 44  TGIICTIGPASRSVDKLKEMIKSGMNVARLNFSHGTHEYHEGTIKNVREATESFASDPIT 103

Query: 409 KKLCAVMLDTVGPELQ---VVNKSEVTISLEENESVVLTPHKG--QEASSKLLPINFSGL 573
            +  A+ LDT GPE++   +       + L++  ++ +T      +     +L +++  L
Sbjct: 104 YRPVAIALDTKGPEIRTGLIKGSGTAEVELKKGAALKVTLDNAFMENCDENVLWVDYKNL 163

Query: 574 AKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIH 753
            K +  G+ I+V   L +        L V E   D V+  ++N   L GS   ++     
Sbjct: 164 IKVIDVGSKIYVDDGLIS--------LLVKEKGKDFVMTEVENGGML-GSKKGVNLPGAA 214

Query: 754 IDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIE 933
           +D+P +S++D   + K+G    +D +  S+ R A DV   R+ L + G      I +KIE
Sbjct: 215 VDLPAVSEKDIQDL-KFGVEQNVDMVFASFIRKAADVHAVRKVLGEKG--KHIKIISKIE 271

Query: 934 NVEVISRY 957
           N E + R+
Sbjct: 272 NHEGVRRF 279

to top

>Q6FV12:KPYK2_CANGA Pyruvate kinase 2 - Candida glabrata (Yeast) (Torulopsis glabrata)|
          Length = 508

 Score =  155 bits (391), Expect(2) = 4e-61
 Identities = 84/213 (39%), Positives = 130/213 (61%), Gaps = 2/213 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FDEILE A G++++RG+LGI++P  +V   QK  + KCN+AGKP +  T++++SM
Sbjct: 246  QGVNNFDEILEVAHGVMVARGDLGIEIPAPQVLAVQKKLIAKCNLAGKPVICATQMLESM 305

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NA+LDG+D ++L  ET +G YP+  ++T+      AE+       
Sbjct: 306  TFNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAIIAERAIAYMPL 365

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            +        +P +  E++A+SAV A  +  A +I+  ++SG  ARL++KYRP  P++ V 
Sbjct: 366  YDDLRNCTPKPTSTTETVAASAVAAVQEQGAKLILVLSTSGNTARLVSKYRPQCPIVLVT 425

Query: 1616 -IPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
              PR               AR S + RG+FP +
Sbjct: 426  RNPR--------------TARFSHLFRGVFPFV 444



 Score =  103 bits (256), Expect(2) = 4e-61
 Identities = 66/241 (27%), Positives = 123/241 (51%), Gaps = 4/241 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA-TKKLCA 423
           T I+GT+GPK+ +V+ + A  KAG+++ R +FS G   YHQ  ++N + + +    +  A
Sbjct: 22  TAIIGTIGPKTNNVDTLVALRKAGLNIVRMNFSHGSYEYHQSVIDNARKSEQVYPGRPLA 81

Query: 424 VMLDTVGPELQV-VNKSEVTISLEENESVVLTPHK--GQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++   N  +V   +  N  ++ T      +    K++ +++  + K ++PG
Sbjct: 82  IALDTKGPEIRTGTNVDDVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVIQPG 141

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             I+V   + +         EV EV  D  + V   +A    S   ++     +D+P LS
Sbjct: 142 KVIYVDDGVLS--------FEVLEVVDDKTLKVKSLNAGKISSHKGVNLPGTDVDLPALS 193

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           ++DK+ + ++G  N +  +  S+ R A+DV   RE L + G      +  KIEN + ++ 
Sbjct: 194 EKDKEDL-RFGVKNGVHMIFASFIRTAQDVLTIREVLGEEG--KDIKVIVKIENQQGVNN 250

Query: 955 Y 957
           +
Sbjct: 251 F 251

to top

>P30613:KPYR_HUMAN Pyruvate kinase isozymes R/L - Homo sapiens (Human)|
          Length = 574

 Score =  160 bits (404), Expect(2) = 6e-61
 Identities = 94/215 (43%), Positives = 135/215 (62%), Gaps = 4/215 (1%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN+AGKP V  T++++SM
Sbjct: 318  EGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESM 377

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAE-KVFNQDL 1432
                RPTRAE +DVANAVLDG+D I+L  ET +G +PVE +     I  EAE  V+++ L
Sbjct: 378  ITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQL 437

Query: 1433 Y--FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVL 1606
            +   +R      +P    E  A  AV AA K  A+ II  T++GR+A+L+++YRP   V+
Sbjct: 438  FEELRRAAPLSRDP---TEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVI 494

Query: 1607 SVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
            +V                A  ARQ  + RG+FP+L
Sbjct: 495  AVT-------------RSAQAARQVHLCRGVFPLL 516



 Score = 97.4 bits (241), Expect(2) = 6e-61
 Identities = 72/249 (28%), Positives = 126/249 (50%), Gaps = 12/249 (4%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA------T 408
           T I+ T+GP SRSVE +   +KAGM++AR +FS G   YH E++ N++ A+++      +
Sbjct: 88  TSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLS 147

Query: 409 KKLCAVMLDTVGPE-----LQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGL 573
            +  A+ LDT GPE     LQ   +SEV +       V + P      ++  + +++  +
Sbjct: 148 YRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNI 207

Query: 574 AKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIH 753
            + V  G  I++   L +        L V ++  + +V  ++N   L GS   ++     
Sbjct: 208 VRVVPVGGRIYIDDGLIS--------LVVQKIGPEGLVTQVENGGVL-GSRKGVNLPGAQ 258

Query: 754 IDMPTLSDED-KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKI 930
           +D+P LS++D +D+  ++G  + +D +  S+ R A DV   R  L   G      I +KI
Sbjct: 259 VDLPGLSEQDVRDL--RFGVEHGVDIVFASFVRKASDVAAVRAALGPEG--HGIKIISKI 314

Query: 931 ENVEVISRY 957
           EN E + R+
Sbjct: 315 ENHEGVKRF 323

to top

>P12928:KPYR_RAT Pyruvate kinase isozymes R/L - Rattus norvegicus (Rat)|
          Length = 574

 Score =  158 bits (399), Expect(2) = 1e-60
 Identities = 93/215 (43%), Positives = 134/215 (62%), Gaps = 4/215 (1%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN+AGKP V  T++++SM
Sbjct: 318  EGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESM 377

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAE-KVFNQDL 1432
                RPTRAE +DVANAVLDG+D I+L  ET +G +PVE +     I  EAE  V+++ L
Sbjct: 378  ITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQL 437

Query: 1433 Y--FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVL 1606
            +   +R      +P    E  A  AV A+ K  A+ II  T +GR+A+L+++YRP   V+
Sbjct: 438  FEELRRAAPLSRDP---TEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVI 494

Query: 1607 SVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
            +V                A  ARQ  + RG+FP+L
Sbjct: 495  AVT-------------RSAQAARQVHLSRGVFPLL 516



 Score = 98.2 bits (243), Expect(2) = 1e-60
 Identities = 73/248 (29%), Positives = 124/248 (50%), Gaps = 11/248 (4%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIK--ATKKL- 417
           T I+ T+GP SRSV+ +   +KAGM++AR +FS G   YH E++ N++ A +  AT  L 
Sbjct: 88  TSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLS 147

Query: 418 ---CAVMLDTVGPE-----LQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGL 573
               A+ LDT GPE     LQ   +SEV I       V + P       +K + +++  +
Sbjct: 148 YRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNI 207

Query: 574 AKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIH 753
            + V  G  I++   L +        L V ++  + +V  +++   L GS   ++     
Sbjct: 208 TRVVAVGGRIYIDDGLIS--------LVVQKIGPEGLVTEVEHGGIL-GSRKGVNLPNTE 258

Query: 754 IDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIE 933
           +D+P LS++D  +  ++G  + +D +  S+ R A DV   R+ L   G      I +KIE
Sbjct: 259 VDLPGLSEQDL-LDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEG--QNIKIISKIE 315

Query: 934 NVEVISRY 957
           N E + ++
Sbjct: 316 NHEGVKKF 323

to top

>Q29536:KPYR_CANFA Pyruvate kinase isozyme R - Canis familiaris (Dog)|
          Length = 519

 Score =  162 bits (409), Expect(2) = 1e-60
 Identities = 94/215 (43%), Positives = 136/215 (63%), Gaps = 4/215 (1%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN+AGKP V  T++++SM
Sbjct: 263  EGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESM 322

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAE-KVFNQDL 1432
                RPTRAE +DVANAVLDG+D I+L  ET +G +PVE +    RI  EAE  V+++ L
Sbjct: 323  ITKPRPTRAETSDVANAVLDGADCIMLSGETAKGKFPVEAVKMQHRIAREAEAAVYHRQL 382

Query: 1433 Y--FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVL 1606
            +   +R      +P    E  A + V AA K  A+ II  T +GR+A+L+++YRP   V+
Sbjct: 383  FEELRRAAPLSRDP---TEVTAIATVEAAFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVI 439

Query: 1607 SVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
            +V                A  ARQ+ + RG+FP+L
Sbjct: 440  AVT-------------RSAQAARQAHLCRGVFPLL 461



 Score = 94.4 bits (233), Expect(2) = 1e-60
 Identities = 71/249 (28%), Positives = 127/249 (51%), Gaps = 12/249 (4%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIK--ATKKL- 417
           T I+ T+GP S SVE +   +KAGM++AR +FS G   YH +++ N++ A++  AT  L 
Sbjct: 33  TSIIATIGPASHSVERLKEMIKAGMNIARLNFSHGSHEYHAQSIANIREAVESFATSPLG 92

Query: 418 ---CAVMLDTVGPELQ---VVNKSEVTISLEENESVVLT--PHKGQEASSKLLPINFSGL 573
               A+ LDT GPE++   +    E  + L +   V++T  P       +  + +++  +
Sbjct: 93  YRPVAIALDTKGPEIRTGVLKGGPETEVELVKGSWVLVTVDPAFRTLGDAHTVWVDYPNI 152

Query: 574 AKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIH 753
            K V  G  IF+   L +        L+V ++    +   ++N   L GS   ++     
Sbjct: 153 VKVVPVGGRIFIDDGLIS--------LQVKKIDRKGLETQVENGG-LLGSRKGVNLPGAE 203

Query: 754 IDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTL-IFAKI 930
           +D+P LS++D   + ++G  + +D +  S+ R A DV   R   + LG   +T+ I +KI
Sbjct: 204 VDLPGLSEQDAQDL-RFGVEHNVDIVFASFVRKASDVAAIR---AALGPEGRTIKIISKI 259

Query: 931 ENVEVISRY 957
           EN E + ++
Sbjct: 260 ENHEGVKKF 268

to top

>Q10208:KPYK_SCHPO Pyruvate kinase - Schizosaccharomyces pombe (Fission yeast)|
          Length = 509

 Score =  155 bits (393), Expect(2) = 3e-60
 Identities = 88/222 (39%), Positives = 138/222 (62%), Gaps = 3/222 (1%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKP-AVVTRVVDSM 1255
            QG+N+FD IL+  DGI+++RG+LGI++P  +VF+ QK  + KCN+AGKP A  T++++SM
Sbjct: 252  QGVNNFDSILDVTDGIMVARGDLGIEIPASQVFVAQKMMIAKCNIAGKPVACATQMLESM 311

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NAVLDG+D ++L  ET +G YPVE ++ +      AE        
Sbjct: 312  TYNPRPTRAEVSDVGNAVLDGADLVMLSGETTKGSYPVEAVTYMAETARVAEASIPYGSL 371

Query: 1436 FKRTVKYVGEPM-THLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            ++     V  P+    E+ A +A+ A+I+  A  I+  ++SG  ARL +KYRP++P++ V
Sbjct: 372  YQEMFGLVRRPLECATETTAVAAIGASIESDAKAIVVLSTSGNTARLCSKYRPSIPIVMV 431

Query: 1613 V-IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPVS 1735
               P+               ARQS + RG++P++ + + P+S
Sbjct: 432  TRCPQ--------------RARQSHLNRGVYPVIYE-KEPLS 458



 Score = 99.4 bits (246), Expect(2) = 3e-60
 Identities = 68/242 (28%), Positives = 123/242 (50%), Gaps = 5/242 (2%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKL--C 420
           T I+ T+GPKS +VE +     AGM++ R +FS G   YHQ  ++N + A  AT  L   
Sbjct: 28  TSIICTIGPKSNNVETLCKLRDAGMNIVRMNFSHGSYEYHQSVIDNARKA-SATNPLFPL 86

Query: 421 AVMLDTVGPELQ---VVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKP 591
           A+ LDT GPE++    V  ++  IS              ++ + K++ I++  + K ++P
Sbjct: 87  AIALDTKGPEIRTGLTVGGTDYPISSGHEMIFTTDDAYAEKCNDKVMYIDYKNITKVIQP 146

Query: 592 GATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTL 771
           G  I+V   + +       +  + +V   ++   + N+  ++ S   ++  +  +D+P L
Sbjct: 147 GRIIYVDDGILS-------FTVIEKVDDKNLKVRVNNNGKIS-SKKGVNLPKTDVDLPAL 198

Query: 772 SDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVIS 951
           S++DK  + ++G  N +D +  S+ R AEDV   RE L + G      I  KIEN + ++
Sbjct: 199 SEKDKADL-RFGVKNGVDMIFASFIRRAEDVIHIREVLGEEG--KNIKIICKIENQQGVN 255

Query: 952 RY 957
            +
Sbjct: 256 NF 257

to top

>P53657:KPYR_MOUSE Pyruvate kinase isozymes R/L - Mus musculus (Mouse)|
          Length = 574

 Score =  159 bits (402), Expect(2) = 2e-59
 Identities = 93/215 (43%), Positives = 134/215 (62%), Gaps = 4/215 (1%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            +G+  FDEILE +DGI+++RG+LGI++P EKVFL QK  + +CN+AGKP V  T++++SM
Sbjct: 318  EGVKKFDEILEVSDGIMMARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESM 377

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAE-KVFNQDL 1432
                RPTRAE +DVANAVLDG+D I+L  ET +G +PVE +     I  EAE  V+++ L
Sbjct: 378  ITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVKMQHAIAREAEAAVYHRQL 437

Query: 1433 Y--FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVL 1606
            +   +R      +P    E  A  AV A+ K  A+ II  T +GR+A+L+++YRP   V+
Sbjct: 438  FEELRRAAPLSRDP---TEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVI 494

Query: 1607 SVVIPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
            +V                A  ARQ  + RG+FP+L
Sbjct: 495  AVT-------------RSAQAARQVHLSRGVFPLL 516



 Score = 93.6 bits (231), Expect(2) = 2e-59
 Identities = 72/248 (29%), Positives = 124/248 (50%), Gaps = 11/248 (4%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIK--ATKKL- 417
           T I+ T+GP SRSV+ +   +KAGM++AR +FS G   YH E++ N++ A +  AT  L 
Sbjct: 88  TSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREAAESFATSPLS 147

Query: 418 ---CAVMLDTVGPE-----LQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGL 573
               A+ LDT GPE     LQ   +SEV I       V + P       +K + +++  +
Sbjct: 148 YRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFRTRGDAKTVWVDYHNI 207

Query: 574 AKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIH 753
            + V  G  I++   L +        L V ++  + +V  +++   L G+   ++     
Sbjct: 208 TQVVAVGGRIYIDDGLIS--------LVVRKIGPEGLVTEVEHGGFL-GNRKGVNLPNAE 258

Query: 754 IDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIE 933
           +D+P LS++D  +  ++G  + +D +  S+ R A DV   R+ L   G      I +KIE
Sbjct: 259 VDLPGLSEQDL-LDLRFGVEHYVDIIFASFVRKASDVVAVRDALGPEG--RGIKIISKIE 315

Query: 934 NVEVISRY 957
           N E + ++
Sbjct: 316 NHEGVKKF 323

to top

>Q875S4:KPYK_SACKL Pyruvate kinase - Saccharomyces kluyveri (Yeast) (Saccharomyces|
            silvestris)
          Length = 501

 Score =  155 bits (393), Expect(2) = 2e-58
 Identities = 82/213 (38%), Positives = 131/213 (61%), Gaps = 2/213 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FDEIL+  DG++++RG+LGI++P  +VF  QK  + KCN+AGKP +  T++++SM
Sbjct: 246  QGVNNFDEILKVTDGVMVARGDLGIEIPAPQVFAVQKKLIAKCNLAGKPVICATQMLESM 305

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NAVLDG+D ++L  ET +G YP+  ++ +      AE+       
Sbjct: 306  TYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGNYPINAVTIMAETALIAEQAIPYVAT 365

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            +     +  +P +  E+IA++AV +  + KA  II  +++G   RL++KY+P +P++ V 
Sbjct: 366  YDDLRNFTPKPTSTTETIAAAAVSSVFEQKAKAIIVLSTTGDTPRLVSKYKPNVPIVMVT 425

Query: 1616 -IPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
              PR               AR S + RG+FP +
Sbjct: 426  RNPR--------------AARFSHLYRGVFPFV 444



 Score = 93.2 bits (230), Expect(2) = 2e-58
 Identities = 65/241 (26%), Positives = 120/241 (49%), Gaps = 4/241 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA-TKKLCA 423
           T I+GT+GPK+ + E + A  KAG+++ R +FS G   YHQ  ++N + + +    +  A
Sbjct: 22  TSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHQSVIDNARKSEELYPGRPLA 81

Query: 424 VMLDTVGPELQV-VNKSEVTISLEENESVV--LTPHKGQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++     +EV   +  N  ++  +     +    K++ I++  + K ++ G
Sbjct: 82  IALDTKGPEIRTGTTTNEVDYPIPPNHEMIFSIDDKYAKACDDKVMYIDYKNITKVIEKG 141

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             I+V   + +         EV EV  +  + V   +A    S   ++     +D+P LS
Sbjct: 142 KIIYVDDGVLS--------FEVLEVVDEQTLKVKSLNAGKICSHKGVNLPGTDVDLPALS 193

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           ++DK  + ++G  N +  +  S+ R A+DV   RE L +  D     I  KIEN + ++ 
Sbjct: 194 EKDKSDL-RFGVKNGVHMVFASFIRTAQDVLTIREVLGE--DGKDVKIIVKIENQQGVNN 250

Query: 955 Y 957
           +
Sbjct: 251 F 251

to top

>Q875M9:KPYK_KLULA Pyruvate kinase - Kluyveromyces lactis (Yeast) (Candida sphaerica)|
          Length = 501

 Score =  155 bits (393), Expect(2) = 4e-58
 Identities = 83/215 (38%), Positives = 131/215 (60%), Gaps = 2/215 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FD+IL+  DG++++RG+LGI++P  +VF  QK  + KCN+AGKP +  T++++SM
Sbjct: 246  QGVNNFDDILKVTDGVMVARGDLGIEIPAPQVFAVQKKLIAKCNLAGKPVICATQMLESM 305

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NAVLDG+D ++L  ET +G YP+  + T+      AE+       
Sbjct: 306  TYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGNYPINAVKTMAETALIAEQAIPYIPT 365

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            +        +P +  E+IA+++V A  + KA  +I  +++G   RL+AKY+P +P++ V 
Sbjct: 366  YDDLRNLTPKPTSTTETIAAASVSAVFEQKARALIVLSTTGDTPRLVAKYKPNVPIVMVT 425

Query: 1616 -IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLAD 1717
              PR               AR S + RG+FP + D
Sbjct: 426  RNPR--------------AARFSHLYRGVFPFVYD 446



 Score = 92.4 bits (228), Expect(2) = 4e-58
 Identities = 65/241 (26%), Positives = 119/241 (49%), Gaps = 4/241 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATK-KLCA 423
           T I+ T+GPK+ + E +    KAGM++ R +FS G   YHQ  ++N + + +  + +  A
Sbjct: 22  TSIICTIGPKTNNPETLVELRKAGMNIVRMNFSHGSYEYHQSVIDNARKSEELYQGRPLA 81

Query: 424 VMLDTVGPELQV-VNKSEVTISLEENESVVLTPHK--GQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++     ++V   +  N  ++ T      +    K + +++  + K ++ G
Sbjct: 82  IALDTKGPEIRTGTTTNDVDYPIPPNHEMIFTTDDKYAKACDDKTMYVDYKNITKVIEAG 141

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             I+V   + +         EV EV  D+ + V   +A    S   ++     +D+P LS
Sbjct: 142 RIIYVDDGVLS--------FEVLEVIDDNTLKVKSLNAGKICSHKGVNLPGTDVDLPALS 193

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           ++DK  + K+G  N +  +  S+ R A+DV   RE L + G      I  KIEN + ++ 
Sbjct: 194 EKDKSDL-KFGVKNGVHMVFASFIRTAQDVLTIREVLGEQG--KDIKIIVKIENQQGVNN 250

Query: 955 Y 957
           +
Sbjct: 251 F 251

to top

>P00549:KPYK1_YEAST Pyruvate kinase 1 - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 500

 Score =  155 bits (392), Expect(2) = 5e-58
 Identities = 86/221 (38%), Positives = 133/221 (60%), Gaps = 2/221 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FDEIL+  DG++++RG+LGI++P  +V   QK  + K N+AGKP +  T++++SM
Sbjct: 245  QGVNNFDEILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESM 304

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NA+LDG+D ++L  ET +G YP+  ++T+      AE+       
Sbjct: 305  TYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAVIAEQAIAYLPN 364

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            +        +P +  E++A+SAV A  + KA  II  ++SG   RL++KYRP  P++ V 
Sbjct: 365  YDDMRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVT 424

Query: 1616 -IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPRHPVS 1735
              PR               AR S + RG+FP + + + PVS
Sbjct: 425  RCPR--------------AARFSHLYRGVFPFVFE-KEPVS 450



 Score = 92.4 bits (228), Expect(2) = 5e-58
 Identities = 63/241 (26%), Positives = 119/241 (49%), Gaps = 4/241 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA-TKKLCA 423
           T I+GT+GPK+ + E + A  KAG+++ R +FS G   YH+  ++N + + +    +  A
Sbjct: 21  TSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYPGRPLA 80

Query: 424 VMLDTVGPELQV-VNKSEVTISLEENESVVLTPHK--GQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++     ++V   +  N  ++ T      +    K++ +++  + K +  G
Sbjct: 81  IALDTKGPEIRTGTTTNDVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVISAG 140

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             I+V   + +         +V EV  D  + V   +A    S   ++     +D+P LS
Sbjct: 141 RIIYVDDGVLS--------FQVLEVVDDKTLKVKALNAGKICSHKGVNLPGTDVDLPALS 192

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           ++DK+ + ++G  N +  +  S+ R A DV   RE L + G      I  KIEN + ++ 
Sbjct: 193 EKDKEDL-RFGVKNGVHMVFASFIRTANDVLTIREVLGEQG--KDVKIIVKIENQQGVNN 249

Query: 955 Y 957
           +
Sbjct: 250 F 250

to top

>Q759A9:KPYK_ASHGO Pyruvate kinase - Ashbya gossypii (Yeast) (Eremothecium gossypii)|
          Length = 501

 Score =  156 bits (394), Expect(2) = 6e-58
 Identities = 75/179 (41%), Positives = 118/179 (65%), Gaps = 1/179 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FDEIL+  DG++++RG+LGI++P  +VF  QK  + KCN+AGKP +  T++++SM
Sbjct: 246  QGVNNFDEILKVTDGVMVARGDLGIEIPAPQVFAVQKMLIAKCNLAGKPVICATQMLESM 305

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NAVLDG+D ++L  ET +G+YP+  + T+      AE+       
Sbjct: 306  TYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGIYPINAVKTMAETALIAEQAIPYVPT 365

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            +        +P    E+IA++AV A  + KA  I+  ++SG   RL++KY+P +P++ V
Sbjct: 366  YDDLRNLTPKPTPTSETIAAAAVAATFEQKAKAIVVLSTSGDTTRLVSKYKPNVPIVMV 424



 Score = 91.3 bits (225), Expect(2) = 6e-58
 Identities = 64/241 (26%), Positives = 117/241 (48%), Gaps = 4/241 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA-TKKLCA 423
           T I+GT+GPK+ + E +    KAG+++ R +FS G   YHQ  ++N + + +    +  A
Sbjct: 22  TSIIGTIGPKTNNPETLVELRKAGLNIVRMNFSHGSYEYHQSVIDNARKSEELYPGRPLA 81

Query: 424 VMLDTVGPELQV-VNKSEVTISLEENESVVLT--PHKGQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++       V   +  N  ++ T      +    K++ +++  + K ++ G
Sbjct: 82  IALDTKGPEIRTGTTVDNVDYPIPPNHEMIFTTDDQYAKSCDDKVMFVDYKNITKVIEKG 141

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             I+V   + +         EV EV  D  + V   +A    S   ++     +D+P LS
Sbjct: 142 RVIYVDDGVLS--------FEVLEVVDDKTLKVKSLNAGKICSHKGVNLPGTDVDLPALS 193

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           ++DK  + ++G  N +  +  S+ R A D+   RE L +  D     I AKIEN + ++ 
Sbjct: 194 EKDKSDL-RFGVKNGVHMVFASFIRTAGDILTIREILGE--DGKDIKIIAKIENQQGVNN 250

Query: 955 Y 957
           +
Sbjct: 251 F 251

to top

>P52489:KPYK2_YEAST Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 506

 Score =  153 bits (387), Expect(2) = 2e-57
 Identities = 81/216 (37%), Positives = 128/216 (59%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QGL++FDEILE  DG++++RG+LGI++   +V   QK  + KCN+AGKP +  T+++DSM
Sbjct: 247  QGLDNFDEILEVTDGVMIARGDLGIEILAPEVLAIQKKLIAKCNLAGKPVICATQMLDSM 306

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NAVLDG+D ++L  ET +G YPV  ++ +      AE        
Sbjct: 307  THNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGDYPVNAVNIMAATALIAESTIAHLAL 366

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            +        +P +  E++A++A  A ++     I+  +++G  ARL++KYRP+ P++ V 
Sbjct: 367  YDDLRDATPKPTSTTETVAAAATAAILEQDGKAIVVLSTTGNTARLLSKYRPSCPIILVT 426

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
                           A  AR + + RG+FP L +P+
Sbjct: 427  -------------RHARTARIAHLYRGVFPFLYEPK 449



 Score = 92.4 bits (228), Expect(2) = 2e-57
 Identities = 68/245 (27%), Positives = 124/245 (50%), Gaps = 8/245 (3%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKL--- 417
           T I+GT+GPK+ S EAI+A  KAG+++ R +FS G   +HQ  +EN   A+K+ ++    
Sbjct: 23  TSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFHQSVIEN---AVKSEQQFPGR 79

Query: 418 -CAVMLDTVGPEL---QVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAV 585
             A+ LDT GPE+   + +N  ++ I ++              ++ K++ I+++ L K +
Sbjct: 80  PLAIALDTKGPEIRTGRTLNDQDLYIPVDHQMIFTTDASFANTSNDKIMYIDYANLTKVI 139

Query: 586 KPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMP 765
            PG  I+V   + +         +V ++  +  + V   ++    S   ++     +D+P
Sbjct: 140 VPGRFIYVDDGILS--------FKVLQIIDESNLRVQAVNSGYIASHKGVNLPNTDVDLP 191

Query: 766 TLSDED-KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVE 942
            LS +D KD+  ++G  N I  +  S+ R +EDV   R+ L   G      I +KIEN +
Sbjct: 192 PLSAKDMKDL--QFGVRNGIHIVFASFIRTSEDVLSIRKALGSEG--QDIKIISKIENQQ 247

Query: 943 VISRY 957
            +  +
Sbjct: 248 GLDNF 252

to top

>Q6FIS9:KPYK1_CANGA Pyruvate kinase 1 - Candida glabrata (Yeast) (Torulopsis glabrata)|
          Length = 501

 Score =  154 bits (388), Expect(2) = 2e-57
 Identities = 83/212 (39%), Positives = 127/212 (59%), Gaps = 1/212 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FDEIL+  D ++++RG+LGI++P  +V   QK  + K N+AGKP +  T++++SM
Sbjct: 246  QGVNNFDEILKVTDAVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESM 305

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NAVLDG+D ++L  ET +G YP+  ++T+      AE+       
Sbjct: 306  TYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGNYPINAVTTMAETALIAEQAIAYLPN 365

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            +        +P +  E++A+SAV A  + KA  II  ++SG  ARL++KYRP  P++ V 
Sbjct: 366  YDDIRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTARLVSKYRPNCPIILVT 425

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
                           A  AR S + RG+FP +
Sbjct: 426  -------------RNARTARFSHLYRGVFPFV 444



 Score = 91.7 bits (226), Expect(2) = 2e-57
 Identities = 64/241 (26%), Positives = 119/241 (49%), Gaps = 4/241 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA-TKKLCA 423
           T I+GT+GPK+ + E + A  KAG+++ R +FS G   YH+  ++N + + +    +  A
Sbjct: 22  TSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYPGRPLA 81

Query: 424 VMLDTVGPELQV-VNKSEVTISLEENESVVLTPHK--GQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++     +EV   +  N  ++ T      +    K++ +++  + K +  G
Sbjct: 82  IALDTKGPEIRTGTTTNEVDYPIPPNHEMIFTTDDKYAKACDDKIMYLDYKNITKVISAG 141

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             I+V   + +         EV +V  D  + V   +A    S   ++     +D+P LS
Sbjct: 142 RIIYVDDGVLS--------FEVLQVVDDKTLKVKSLNAGKICSHKGVNLPGTDVDLPALS 193

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           ++DK  + ++G  N +  +  S+ R A+DV   RE L +  D     I  KIEN + ++ 
Sbjct: 194 EKDKADL-RFGVENGVHMIFASFIRTAQDVLTIREVLGE--DGKDIKIVVKIENQQGVNN 250

Query: 955 Y 957
           +
Sbjct: 251 F 251

to top

>Q6BS75:KPYK_DEBHA Pyruvate kinase - Debaryomyces hansenii (Yeast) (Torulaspora|
            hansenii)
          Length = 504

 Score =  152 bits (384), Expect(2) = 7e-57
 Identities = 75/179 (41%), Positives = 114/179 (63%), Gaps = 1/179 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FDEIL E DG++++RG+LGI++P  +VF+ QK  + KCN+A KP +  T++++SM
Sbjct: 249  QGVNNFDEILVETDGVMVARGDLGIEIPAPQVFVVQKQLIAKCNLAAKPVICATQMLESM 308

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NA+LDG+D ++L  ET +G YP E +S +      AEK       
Sbjct: 309  TYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPFEAVSMMHNTAIIAEKAIAYQPL 368

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
                      P    E+ A ++V AA +  A  I+  ++SG  +RL++KY+P +PV+ V
Sbjct: 369  HNEIRSLANRPTPTTETCAMASVSAAYEQDAKAIVVLSTSGFTSRLVSKYKPNVPVMMV 427



 Score = 91.7 bits (226), Expect(2) = 7e-57
 Identities = 63/242 (26%), Positives = 125/242 (51%), Gaps = 5/242 (2%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATK-KLCA 423
           + I+GT+GPK+ +V+ +    KAG+++ R +FS G   YHQ  ++N K + +  K +  A
Sbjct: 25  SSIIGTIGPKTNNVDVLVKLRKAGLNIVRMNFSHGSYEYHQSVIDNAKQSEEIYKGRPLA 84

Query: 424 VMLDTVGPELQV-VNKSEVTISLEENESVVLTPHK--GQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++      +    +  N  ++ T  +   ++   K++ I++  + K ++ G
Sbjct: 85  IALDTKGPEIRTGTTIDDKDYPILPNHEMIFTTDEAYAKKCDDKVMFIDYKNITKVIEAG 144

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             I++        +   V  EV ++  D  + V   ++    S   ++     +D+P LS
Sbjct: 145 KIIYI--------DDGVVSFEVLQIVDDKTLKVRSVNSGKICSHKGVNLPGTDVDLPALS 196

Query: 775 DEDK-DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVIS 951
           ++DK D+  K+G  N +  +  S+ R  +D+++ R+ L + G   Q  I AKIEN + ++
Sbjct: 197 EKDKADI--KFGVKNGVHMIFASFIRTGDDIKEIRKVLGEEGKDIQ--IIAKIENQQGVN 252

Query: 952 RY 957
            +
Sbjct: 253 NF 254

to top

>Q875Z9:KPYK_SACCA Pyruvate kinase - Saccharomyces castellii (Yeast)|
          Length = 501

 Score =  150 bits (379), Expect(2) = 3e-56
 Identities = 82/213 (38%), Positives = 127/213 (59%), Gaps = 2/213 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+N+FDEIL+  D ++++RG+LGI++P  +V   QK  + K N+AGKP +  T++++SM
Sbjct: 246  QGVNNFDEILKVTDAVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESM 305

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DV NA+LDG+D ++L  ET +G YP+  ++T+      AE+       
Sbjct: 306  TYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMADTALIAEQAIAYQPL 365

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            +        +P +  E++A+SAV A  + KA  II  ++SG   RL++KYRP  P++ V 
Sbjct: 366  YDDLRNLTPKPTSTTETVAASAVAAVYEQKAKAIIVLSTSGTTPRLVSKYRPDCPIILVT 425

Query: 1616 -IPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
              PR               AR S + RG+FP +
Sbjct: 426  RNPR--------------AARFSHLSRGVFPFV 444



 Score = 91.3 bits (225), Expect(2) = 3e-56
 Identities = 65/241 (26%), Positives = 119/241 (49%), Gaps = 4/241 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKA-TKKLCA 423
           T I+GT+GPK+ + E + A  KAG+++ R +FS G   YHQ  +EN + + +    +  A
Sbjct: 22  TSIIGTIGPKTNNPEVLVALRKAGLNIVRMNFSHGSYEYHQSVIENARKSEELYPGRPLA 81

Query: 424 VMLDTVGPELQV-VNKSEVTISLEENESVVLTPHK--GQEASSKLLPINFSGLAKAVKPG 594
           + LDT GPE++      EV   +  N  ++ +  +   +    K++ ++++ + K +  G
Sbjct: 82  IALDTKGPEIRTGTTTGEVDYPIPPNHEMIFSTDEKYAKACDDKVMFVDYANITKVISKG 141

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             I+V   + +         EV EV     + V   +A    S   ++     +D+P LS
Sbjct: 142 KIIYVDDGVLS--------FEVLEVVDGKTLKVKSLNAGKICSHKGVNLPGTDVDLPALS 193

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           ++DK  + ++G  N +  +  S+ R A+DV   RE L +  D     I  KIEN + ++ 
Sbjct: 194 EKDKADL-RFGVKNGVHMVFASFIRTAQDVLTIREVLGE--DGKDIKIVVKIENQQGVNN 250

Query: 955 Y 957
           +
Sbjct: 251 F 251

to top

>O44006:KPYK_EIMTE Pyruvate kinase - Eimeria tenella|
          Length = 531

 Score =  189 bits (479), Expect = 7e-47
 Identities = 92/192 (47%), Positives = 135/192 (70%), Gaps = 1/192 (0%)
 Frame = +2

Query: 1073 SLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVD 1249
            +++GL +FDEIL+EADGI+++RG+LG+++PPEKVFL QK  + KCN+AGKP +  T++++
Sbjct: 278  NVEGLLNFDEILQEADGIMIARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLE 337

Query: 1250 SMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQD 1429
            SMT N RPTRAEA DVANAVLDG+D ++L  ET  G +PV+ ++ + R+C EAE   +  
Sbjct: 338  SMTKNPRPTRAEAADVANAVLDGTDCVMLSGETANGSFPVQAVTVMSRVCFEAEGCIDYQ 397

Query: 1430 LYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLS 1609
              F+ T +    P+   E++A +AV  A  + AS+I+  T +GR ARLIAKYRP  P+L+
Sbjct: 398  QVFRATCQATMTPIDTQEAVARAAVETAQSINASLILALTETGRTARLIAKYRPMQPILA 457

Query: 1610 VVIPRLKTNQLK 1645
            +        QL+
Sbjct: 458  LSASEETIKQLQ 469



 Score =  107 bits (266), Expect = 3e-22
 Identities = 78/253 (30%), Positives = 128/253 (50%), Gaps = 3/253 (1%)
 Frame = +1

Query: 193 IRMVSILEPSKPNFFPA-MTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQ 369
           IRM  ILE  +   F A  TKIV T+GP    V+ +   + AGM+V R +FS GD   H 
Sbjct: 39  IRMSQILEHHEDEDFSAHRTKIVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHG 98

Query: 370 ETLENLKIAIKATK-KLCAVMLDTVGPELQV-VNKSEVTISLEENESVVLTPHKGQEASS 543
             ++NL+ A+K    K  A++LDT GPE++  + + +  I L   + + +        + 
Sbjct: 99  RVVKNLQEALKQRPGKRVALLLDTKGPEIRTGMLEGDKPIELHAGDMLKIVTDYSFVGNK 158

Query: 544 KLLPINFSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGS 723
             +  ++  L  +VKPG TI +           S+ +EV E   D V+  + N A + G+
Sbjct: 159 SCIACSYEKLPSSVKPGNTILIAD--------GSLSVEVVECGKDYVMTRVMNPA-IIGN 209

Query: 724 LFTLHCSQIHIDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDL 903
              ++   + +D+P + ++DK+ +  +G P   +F++ S+ + A+DVR  R  L   G  
Sbjct: 210 KKNMNLPGVKVDLPVIGEKDKNDILNFGIPMGCNFIAASFVQSADDVRYIRSILGTKG-- 267

Query: 904 SQTLIFAKIENVE 942
               I  KIENVE
Sbjct: 268 RNIKIIPKIENVE 280

to top

>Q27686:KPYK_LEIME Pyruvate kinase - Leishmania mexicana|
          Length = 499

 Score =  169 bits (427), Expect = 7e-41
 Identities = 82/186 (44%), Positives = 127/186 (68%), Gaps = 1/186 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+ + D I+EE+DGI+++RG+LG+++P EKV + QK  + KCN+AGKP +  T++++SM
Sbjct: 244  QGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISKCNVAGKPVICATQMLESM 303

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DVANAV +G+D ++L  ET +G YP E +  + RIC EA+   N+ ++
Sbjct: 304  TYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSALNEYVF 363

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F    K    PM+  E++  SAV +  + KA  ++  +++G  ARL+AKYRP  P++ V 
Sbjct: 364  FNSIKKLQHIPMSADEAVCGSAVNSVSETKAKAMVVLSNTGAGARLVAKYRPNCPIVCVT 423

Query: 1616 IPRLKT 1633
              RL+T
Sbjct: 424  -TRLQT 428



 Score = 94.0 bits (232), Expect = 3e-18
 Identities = 68/245 (27%), Positives = 119/245 (48%), Gaps = 3/245 (1%)
 Frame = +1

Query: 250 KIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAVM 429
           +I+ T+GP ++SVEA+   +++GMSVAR +FS G   YHQ T+ N++ A        A+ 
Sbjct: 23  RIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIA 82

Query: 430 LDTVGPELQVVNKSEVTISLEENESVVLT--PHKGQEASSKLLPINFSGLAKAVKPGATI 603
           LDT GPE++          +E   +  +T  P    + +     I++  L+K V+PG  I
Sbjct: 83  LDTKGPEIRTGQFVGGDAVMERGATCYVTTDPAFADKGTKDKFYIDYQNLSKVVRPGNYI 142

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVV-CVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           ++   +          L+V   + +  + C + NS T++     ++     +D+P +S +
Sbjct: 143 YIDDGILI--------LQVQSHEDEQTLECTVTNSHTISDRR-GVNLPGCDVDLPAVSAK 193

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISRYS 960
           D+ V  ++G    +D +  S+ R AE V   R+ L   G     +I  KIEN + +    
Sbjct: 194 DR-VDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKG--RDIMIICKIENHQGVQNID 250

Query: 961 FNIPE 975
             I E
Sbjct: 251 SIIEE 255

to top

>Q9Z984:KPYK_CHLPN Pyruvate kinase - Chlamydia pneumoniae (Chlamydophila pneumoniae)|
          Length = 484

 Score =  108 bits (271), Expect(2) = 1e-40
 Identities = 60/179 (33%), Positives = 101/179 (56%), Gaps = 2/179 (1%)
 Frame = +2

Query: 1082 GLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMT 1258
            G+ +F +I + ADGI+++RG+LGI+L   +V   QK         G   V  T++++SM 
Sbjct: 225  GVENFSKIAKLADGIMIARGDLGIELSVVEVPNLQKMMAKVSRETGHFCVTATQMLESMI 284

Query: 1259 DNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYF 1438
             N+ PTRAE +D+ANA+ DGS A++L  ET  G +PV  +  +  +  E EK  + D + 
Sbjct: 285  RNVLPTRAEVSDIANAIYDGSSAVMLSGETASGAHPVAAVKIMRSVILETEKNLSHDSFL 344

Query: 1439 KRTVKYVG-EPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            K        +   +L +I  + ++ A +  A  +I +T SG +   ++KYRP  P+++V
Sbjct: 345  KLDDSNSALQVSPYLSAIGLAGIQIAERADAKALIVYTESGSSPMFLSKYRPKFPIIAV 403



 Score = 80.5 bits (197), Expect(2) = 1e-40
 Identities = 64/238 (26%), Positives = 117/238 (49%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKI+ T+GP + S E ++  L AGM+VAR +FS G    H + +  LK   +  +   A+
Sbjct: 5   TKIICTIGPATNSPEMLAKLLDAGMNVARLNFSHGSHETHGQAIGFLKELREQKRVPLAI 64

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           MLDT GPE+++ N  +  IS+ + + + L       ++   + +   G+   V  GA + 
Sbjct: 65  MLDTKGPEIRLGNIPQ-PISVSQGQKLRLVSSDIDGSAEGGVSLYPKGIFPFVPEGADVL 123

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDK 786
           +        +   +   V   + D +     NS  L  S  +L    + + +P ++++D 
Sbjct: 124 I--------DDGYIHAVVVSSEADSLELEFMNSGLLK-SHKSLSIRGVDVALPFMTEKDI 174

Query: 787 DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISRYS 960
             + K+G    +D ++ S+ R+ ED+   R+ L+ LG+    +I AKIEN   +  +S
Sbjct: 175 ADL-KFGVEQNMDVVAASFVRYGEDIETMRKCLADLGNPKMPII-AKIENRLGVENFS 230

to top

>O62619:KPYK_DROME Pyruvate kinase - Drosophila melanogaster (Fruit fly)|
          Length = 533

 Score =  167 bits (422), Expect = 3e-40
 Identities = 92/213 (43%), Positives = 135/213 (63%), Gaps = 2/213 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+++ DEI+E  DGI+++RG+LGI++P EKVFL QK+ + +CN AGKP +  T++++SM
Sbjct: 278  QGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQKAMIARCNKAGKPVICATQMLESM 337

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
                RPTRAE +DVANAVLDG+D ++L  ET +G YP+E + T+ + C EAE        
Sbjct: 338  VKKPRPTRAEISDVANAVLDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHQNL 397

Query: 1436 FKRTVKYVGE-PMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            F   V+  G    +H  +IA  AV AA K KAS I+  T+SG++A  ++KYRP  P+++V
Sbjct: 398  FNDLVRGAGTIDASHAAAIA--AVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIAV 455

Query: 1613 VIPRLKTNQLKWSFTGAFEARQSLIVRGLFPML 1711
                            A  ARQ+ + RGL P++
Sbjct: 456  T-------------RFAQTARQAHLYRGLVPLI 475



 Score =  105 bits (261), Expect = 1e-21
 Identities = 73/242 (30%), Positives = 129/242 (53%), Gaps = 11/242 (4%)
 Frame = +1

Query: 244 MTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIK-ATKKL- 417
           ++ IV T+GP S SVE +   +  GM++AR +FS G   YH  T+ N++ A+K  + KL 
Sbjct: 47  LSGIVCTIGPASSSVEMLEKMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLG 106

Query: 418 ----CAVMLDTVGPELQ---VVNKSEVTISLEENESVVLTPHKG--QEASSKLLPINFSG 570
                A+ LDT GPE++   +       I L++ E + LT +K   ++ S +++ +++  
Sbjct: 107 YEHPVAIALDTKGPEIRTGLIGGSGTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYEN 166

Query: 571 LAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQI 750
           +   VKPG  +FV   L +        L V EV  D + C ++N  +L GS   ++   +
Sbjct: 167 IVNVVKPGNRVFVDDGLIS--------LIVREVGKDSLTCEVENGGSL-GSRKGVNLPGV 217

Query: 751 HIDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKI 930
            +D+P +S++DK  +  +G   ++D +  S+ R+A  + + R+ L + G      I +KI
Sbjct: 218 PVDLPAVSEKDKSDL-LFGVEQEVDMIFASFIRNAAALTEIRKVLGEKG--KNIKIISKI 274

Query: 931 EN 936
           EN
Sbjct: 275 EN 276

to top

>P30616:KPYK2_TRYBB Pyruvate kinase 2 - Trypanosoma brucei brucei|
          Length = 499

 Score =  162 bits (411), Expect = 5e-39
 Identities = 80/186 (43%), Positives = 126/186 (67%), Gaps = 1/186 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+ + D I+E ++GI+++RG+LG+++P EKV + Q   + KCN+ GKP +  T++++SM
Sbjct: 244  QGVQNIDSIIEASNGIMVARGDLGVEIPAEKVCVAQMCIISKCNVVGKPVICATQMLESM 303

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DVANAVL+G+D ++L  ET +G YP E +  + RIC EA+   +  + 
Sbjct: 304  TSNPRPTRAEVSDVANAVLNGADCVMLSGETAKGKYPNEVVQYMARICVEAQSATHDTVM 363

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F         PM   E++ SSAV +A +V+A  ++  +++GR+ARLI+KYRP  P++ V 
Sbjct: 364  FNSIKNLQKIPMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICVT 423

Query: 1616 IPRLKT 1633
              RL+T
Sbjct: 424  -TRLQT 428



 Score =  100 bits (249), Expect = 3e-20
 Identities = 76/248 (30%), Positives = 123/248 (49%), Gaps = 3/248 (1%)
 Frame = +1

Query: 202 VSILEPSKPNFFPAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLE 381
           +SI EP   +      +IV T+GP ++SVEA+   +K+GMSVAR +FS G   YHQ T+ 
Sbjct: 10  LSIFEPVAKH---RANRIVCTIGPSTQSVEALKNLMKSGMSVARMNFSHGSHEYHQTTIN 66

Query: 382 NLKIAIKATKKLCAVMLDTVGPELQ--VVNKSEVTISLEENESVVLTPHKGQEASSKLLP 555
           N++ A         + LDT GPE++  +    EVT +  +   V   P   +  + +   
Sbjct: 67  NVRAAAAELGLHIGIALDTKGPEIRTGLFKDGEVTFAPGDIVCVTTDPAYEKVGTKEKFY 126

Query: 556 INFSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVV-CVIKNSATLAGSLFT 732
           I++  L KAV  G +I+V   + T        L V   + D  + C + N   L      
Sbjct: 127 IDYPQLTKAVPVGGSIYVDDGVMT--------LRVLSKEDDRTLKCHVNNHHRLTDRR-G 177

Query: 733 LHCSQIHIDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQT 912
           ++     +D+P +S++D+  + ++G    +D +  S+ R AE VR+ R  L + G     
Sbjct: 178 INLPGCEVDLPAVSEKDRKDL-EFGVAQGVDMIFASFIRTAEQVREVRAALGEKG--KDI 234

Query: 913 LIFAKIEN 936
           LI +KIEN
Sbjct: 235 LIISKIEN 242

to top

>P30615:KPYK1_TRYBB Pyruvate kinase 1 - Trypanosoma brucei brucei|
          Length = 499

 Score =  162 bits (411), Expect = 5e-39
 Identities = 80/186 (43%), Positives = 126/186 (67%), Gaps = 1/186 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+ + D I+E ++GI+++RG+LG+++P EKV + Q   + KCN+ GKP +  T++++SM
Sbjct: 244  QGVQNIDSIIEASNGIMVARGDLGVEIPAEKVCVAQMCIISKCNVVGKPVICATQMLESM 303

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N RPTRAE +DVANAVL+G+D ++L  ET +G YP E +  + RIC EA+   +  + 
Sbjct: 304  TSNPRPTRAEVSDVANAVLNGADCVMLSGETAKGKYPNEVVQYMARICVEAQSATHDTVM 363

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F         PM   E++ SSAV +A +V+A  ++  +++GR+ARLI+KYRP  P++ V 
Sbjct: 364  FNSIKNLQKIPMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICVT 423

Query: 1616 IPRLKT 1633
              RL+T
Sbjct: 424  -TRLQT 428



 Score =  102 bits (253), Expect = 1e-20
 Identities = 76/247 (30%), Positives = 123/247 (49%), Gaps = 2/247 (0%)
 Frame = +1

Query: 202 VSILEPSKPNFFPAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLE 381
           +SI EP   +      +IV T+GP ++SVEA+   +K+GMSVAR +FS G   YHQ T+ 
Sbjct: 10  LSIFEPVAKH---RANRIVCTIGPSTQSVEALKNLMKSGMSVARMNFSHGSHEYHQTTIN 66

Query: 382 NLKIAIKATKKLCAVMLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQE--ASSKLLP 555
           N++ A         + LDT GPE++     +  +S    + V +T     E   + +   
Sbjct: 67  NVRAAAAELGLHIGIALDTKGPEIRTGLFKDGEVSFAPGDIVCVTTDPAYEKVGTKEKFY 126

Query: 556 INFSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTL 735
           I++  L  AV+PG +I+V      G  T  V   VS+     + C + N   L      +
Sbjct: 127 IDYPQLTNAVRPGGSIYVDD----GVMTLRV---VSKEDDRTLKCHVNNHHRLTDRR-GI 178

Query: 736 HCSQIHIDMPTLSDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTL 915
           +     +D+P +S++D+  + ++G    +D +  S+ R AE VR+ R  L + G     L
Sbjct: 179 NLPGCEVDLPAVSEKDRKDL-EFGVAQGVDMIFASFIRTAEQVREVRAALGEKG--KDIL 235

Query: 916 IFAKIEN 936
           I +KIEN
Sbjct: 236 IISKIEN 242

to top

>P80885:KPYK_BACSU Pyruvate kinase - Bacillus subtilis|
          Length = 585

 Score =  158 bits (400), Expect = 1e-37
 Identities = 80/181 (44%), Positives = 119/181 (65%), Gaps = 1/181 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++ D ILE +DG++++RG+LG+++P E+V L QK  + KCN  GKP +  T+++DSM
Sbjct: 225  EGVDNIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKCNALGKPVITATQMLDSM 284

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N RPTRAEA+DVANA+ DG+DAI+L  ET  G YPVE + T+  I + +E+  N    
Sbjct: 285  QRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGSYPVEAVQTMHNIASRSEEALNYKEI 344

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
              +    VG  MT  ++I  S    AI + A+ I+  T SG  AR+IAKYRP  P+++V 
Sbjct: 345  LSKRRDQVG--MTITDAIGQSVAHTAINLNAAAIVTPTESGHTARMIAKYRPQAPIVAVT 402

Query: 1616 I 1618
            +
Sbjct: 403  V 403



 Score = 96.7 bits (239), Expect = 5e-19
 Identities = 67/235 (28%), Positives = 125/235 (53%), Gaps = 3/235 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S+E ++  +++GM+VAR +FS GD   H   ++N++ A K   K   +
Sbjct: 4   TKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASKKLGKNVGI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++        I LE  + ++++  +    + K + + + GL   V+ G+TI 
Sbjct: 64  LLDTKGPEIRTHTMENGGIELETGKELIISMDEVVGTTDK-ISVTYEGLVHDVEQGSTIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQG--DDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + LEV +V     ++   + N+ TL      ++   + +++P ++++
Sbjct: 123 LDDGL--------IGLEVLDVDAAKREIKTKVLNNGTLKNKK-GVNVPGVSVNLPGITEK 173

Query: 781 D-KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVE 942
           D +D++  +G    +DF++ S+ R + DV + RE L +  +     I  KIEN E
Sbjct: 174 DARDIV--FGIEQGVDFIAPSFIRRSTDVLEIRELLEE-HNAQDIQIIPKIENQE 225

to top

>P51182:KPYK_BACPY Pyruvate kinase - Bacillus psychrophilus (Sporosarcina psychrophila)|
          Length = 586

 Score =  158 bits (399), Expect = 1e-37
 Identities = 81/189 (42%), Positives = 123/189 (65%), Gaps = 1/189 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++ DEIL  +DG++++RG+LG+++PPE+V L QK+ + KCN AGKP +  T+++DSM
Sbjct: 225  EGVDNIDEILNVSDGLMVARGDLGVEIPPEEVPLVQKNLIEKCNQAGKPVITATQMLDSM 284

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N RPTRAEA+DVANA+ DG+DAI+L  ET  G+YPVE++ T+ RI    E   +    
Sbjct: 285  QRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGIYPVESVQTMDRIALTTEAAIDYRSV 344

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 +     MT  E+I  +A   AI +K   ++  T SG  A++IAKYRP  PV++V 
Sbjct: 345  VSTRRREKHGNMT--EAIGQAAAYTAINLKVKAVLAPTESGHTAKMIAKYRPGCPVIAVT 402

Query: 1616 IPRLKTNQL 1642
               + + +L
Sbjct: 403  SSEMCSRKL 411



 Score = 87.4 bits (215), Expect = 3e-16
 Identities = 64/238 (26%), Positives = 122/238 (51%), Gaps = 6/238 (2%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E +   ++AGM+VAR +FS G+ A H+  +++++   +   K+  +
Sbjct: 4   TKIVCTIGPASESPELLEQLIEAGMNVARLNFSHGNHAEHKARIDSIRKVAREKGKVVGI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  +     + L   + + ++  +  E ++ +  +++  L + V  G+ I 
Sbjct: 64  LLDTKGPEIRTHSMMNGKLELVTGQKIDISMTQ-VEGNNDVFSVSYDKLIEDVNEGSVIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVV-----CVIKNSATLAGSLFTLHCSQIHIDMPTL 771
           +   L              EV G DV       +I NS +L+ +   ++   + + +P +
Sbjct: 123 LDDGLIQ-----------LEVTGKDVARGLIHTLIINSGSLSNNK-GVNIPGVSVQLPGM 170

Query: 772 SDED-KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVE 942
           +++D +D++  +G    +DF++ S+ R A DV + R  L    + S   I  KIEN E
Sbjct: 171 TEKDAEDIL--FGIREGVDFIAASFVRRASDVMEIRALLEN-NNGSNLQIIPKIENQE 225

to top

>Q27788:KPYK_TRYBO Pyruvate kinase - Trypanoplasma borreli|
          Length = 498

 Score =  155 bits (391), Expect = 1e-36
 Identities = 74/177 (41%), Positives = 117/177 (66%), Gaps = 1/177 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAV-VTRVVDSM 1255
            QG+++ D I++ ADGI+++RG+LG+++P EKV + QK  + KCN  GK  +  T+++DSM
Sbjct: 243  QGIDNIDAIIDAADGIMVARGDLGVEIPAEKVVIAQKMIMSKCNKVGKTVICATQMLDSM 302

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T   RPTRAE +DVA +VLDG+D ++L  ET +G YPVET+  + RIC E +        
Sbjct: 303  THGPRPTRAEVSDVAKSVLDGADCVMLSGETAKGKYPVETVVYMSRICCETQVTMWNMAA 362

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVL 1606
            F+        P+   E+I SSAV +  ++ A  I+  T++GR+A +++KYRP +P++
Sbjct: 363  FEAIKNLQSFPLIPEEAICSSAVNSIFELHAKAILVLTNTGRSAHMVSKYRPPVPII 419



 Score =  112 bits (280), Expect = 8e-24
 Identities = 70/237 (29%), Positives = 134/237 (56%), Gaps = 4/237 (1%)
 Frame = +1

Query: 250 KIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAVM 429
           KI+ T+GP S+SVE +   +KAG++VAR +FS G   YHQ+T++N++ A         + 
Sbjct: 26  KIICTIGPSSQSVEVLKDLMKAGLNVARMNFSHGTYEYHQKTIDNVRKAASELGIHVGIA 85

Query: 430 LDTVGPELQVVNKSEVTISLEENESVVLTPHK--GQEASSKLLPINFSGLAKAVKPGATI 603
           LDT GPE++        + +E +++V+LT  +   ++ +++   +++  + K V  G  I
Sbjct: 86  LDTKGPEIRTGLFPAGDVVIEAHKTVILTTDETFKEKGTAEKFYVDYMNITKVVPVGGHI 145

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
           FV   L          L V ++ G D+ CV +N+ T++     ++     +D+P +S  +
Sbjct: 146 FVDDGLLD--------LIVVKISGKDIECVAQNTHTISNRK-GINLPNADVDLPAVS--E 194

Query: 784 KDVMK-KWGAPNKIDFLSLSYTRHAEDVRQARE-FLSKLGDLSQTLIFAKIENVEVI 948
           KD+M  ++GA N++DF+  S+ R+A+ V + R+ F  K+  +++   +  I+N++ I
Sbjct: 195 KDLMDLQFGAKNRVDFVFASFIRNADQVNEVRQAFGGKIAVIAKIENYQGIDNIDAI 251

to top

>P51181:KPYK_BACLI Pyruvate kinase - Bacillus licheniformis|
          Length = 585

 Score =  154 bits (389), Expect = 2e-36
 Identities = 79/193 (40%), Positives = 121/193 (62%), Gaps = 1/193 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++ D ILE +DG++++RG+LG+++P E+V L QK  + KCN  GKP +  T+++DSM
Sbjct: 225  EGVDNIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKCNALGKPVITATQMLDSM 284

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N RPTRAEA+DVANA+ DG+DAI+L  ET  G YPVE + T+  I + +E+  N    
Sbjct: 285  QRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGNYPVEAVQTMHNIASRSEEALNHKKI 344

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +T  ++I  S    AI +  + I+  T SG  AR+I+KYRP  P+++V 
Sbjct: 345  LSARSKQVSMSIT--DAIGQSVAHTAINLDVNAIVTPTESGHTARMISKYRPQAPIVAVT 402

Query: 1616 IPRLKTNQLKWSF 1654
            +    + +L   F
Sbjct: 403  VNDAVSRKLSLVF 415



 Score = 99.0 bits (245), Expect = 9e-20
 Identities = 70/235 (29%), Positives = 123/235 (52%), Gaps = 3/235 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S SVE ++  ++AGM+VAR +FS GD   H   ++N++ A     K   +
Sbjct: 4   TKIVCTIGPASESVEKLTQLMEAGMNVARLNFSHGDFEEHGARIKNIREAAGKLGKDIGI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++       +I L     ++++  +      K + + + GL   V  G+TI 
Sbjct: 64  LLDTKGPEIRTHTMENGSIELAAGSQLIVSMDEVIGTPDK-ISVTYDGLIHDVSVGSTIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQGD--DVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        V LEV+++  D  ++V  + NS TL      ++   + +++P ++++
Sbjct: 123 LDDGL--------VGLEVTDINKDKREIVTKVMNSGTLKNKK-GVNVPGVSVNLPGITEK 173

Query: 781 D-KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVE 942
           D  D++  +G    +DF++ S+ R   DV + RE L +  + +   I  KIEN E
Sbjct: 174 DANDIV--FGIEQGVDFIAASFVRRPSDVLEIRELLEE-HNAADIQIIPKIENQE 225

to top

>Q02499:KPYK_BACST Pyruvate kinase - Bacillus stearothermophilus (Geobacillus|
            stearothermophilus)
          Length = 587

 Score =  151 bits (381), Expect = 2e-35
 Identities = 76/180 (42%), Positives = 120/180 (66%), Gaps = 2/180 (1%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+ + DEILE ADG++++RG+LG+++P E+V L QK  + KCNM GKP +  T+++DSM
Sbjct: 226  EGVANIDEILEAADGLMVARGDLGVEIPAEEVPLIQKLLIKKCNMLGKPVITATQMLDSM 285

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVF-NQDL 1432
              N RPTRAEA+DVANA+ DG+DA++L  ET  G YPVE + T+ +I    E+   ++D+
Sbjct: 286  QRNPRPTRAEASDVANAIFDGTDAVMLSGETAAGQYPVEAVKTMHQIALRTEQALEHRDI 345

Query: 1433 YFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
              +RT +      T  ++I  S    A+ +  + I+  T SG+  +++AKYRP  P+++V
Sbjct: 346  LSQRTKE---SQTTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAPIIAV 402



 Score =  106 bits (265), Expect = 4e-22
 Identities = 75/238 (31%), Positives = 125/238 (52%), Gaps = 3/238 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S SV+ +   ++AGM+VAR +FS GD   H   + N++ A K T +  A+
Sbjct: 5   TKIVCTIGPASESVDKLVQLMEAGMNVARLNFSHGDHEEHGRRIANIREAAKRTGRTVAI 64

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N     I L+E   +V++  +      K + + +  L   V  GA I 
Sbjct: 65  LLDTKGPEIRTHNMENGAIELKEGSKLVISMSEVLGTPEK-ISVTYPSLIDDVSVGAKIL 123

Query: 607 VGQYLFTGSETTSVWLEVSEV--QGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L +        LEV+ V  Q  ++V  + N   L      ++   + +++P ++++
Sbjct: 124 LDDGLIS--------LEVNAVDKQAGEIVTTVLNGGVLKNKK-GVNVPGVKVNLPGITEK 174

Query: 781 DK-DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVIS 951
           D+ D++  +G    IDF++ S+ R A DV + RE L +  D     I AKIEN E ++
Sbjct: 175 DRADIL--FGIRQGIDFIAASFVRRASDVLEIRELL-EAHDALHIQIIAKIENEEGVA 229

to top

>O08309:KPYK_CLOAB Pyruvate kinase - Clostridium acetobutylicum|
          Length = 473

 Score =  149 bits (376), Expect = 6e-35
 Identities = 74/179 (41%), Positives = 117/179 (65%), Gaps = 1/179 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++ D I+E +DGI+++RG++G+++P ++V L QK  + KCN  GKP +  T+++DSM
Sbjct: 224  EGVDNIDAIIEVSDGIMVARGDMGVEIPIQRVPLIQKMIIKKCNAVGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N RPTRAEA+D+ANA+ DG+DAI+L  E+  G YP+E ++T+ +I  EAE   N D +
Sbjct: 284  MRNPRPTRAEASDIANAIFDGTDAIMLSGESANGSYPIEAVTTMAKIAQEAENEINYDKF 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
                 +   E     + I+     AA  ++AS II  T +G  AR ++KYRP  PV++V
Sbjct: 344  LAE--RKGNEKKNTSDVISLGTCTAAADLEASAIITATQTGSTARTVSKYRPKAPVIAV 400



 Score =  108 bits (269), Expect = 2e-22
 Identities = 72/232 (31%), Positives = 121/232 (52%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TK++ T+GP S + E ++A +KAGM+ +R +FS GD A H   +  +K       K  A+
Sbjct: 4   TKMIFTVGPASETEEIVTAFIKAGMNASRHNFSHGDHAEHGGRIALVKKVRAKLNKPVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
            LDT GPE++  + +   + L++     +   +     +    I++  L K VKPG TI 
Sbjct: 64  CLDTKGPEIRTGDFNPSKLELQKGSKFTIVCGEEIVGDATKCSISYKDLYKDVKPGNTIL 123

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDK 786
           +   L        V L V  ++G +V+C + N+  L GS   ++   + I +P ++++DK
Sbjct: 124 IDDGL--------VGLTVEAIEGTNVICTVANTG-LVGSHKGVNVPNVSIQLPAMTEKDK 174

Query: 787 DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVE 942
             +  +G   +ID +S S+ R  EDV   R+ L++ G      IF+KIEN E
Sbjct: 175 SDL-IFGCKEEIDMVSASFIRKPEDVLAIRKVLNENGG-ENIQIFSKIENQE 224

to top

>P0AD61:KPYK1_ECOLI Pyruvate kinase I - Escherichia coli|
          Length = 470

 Score =  149 bits (376), Expect = 6e-35
 Identities = 78/199 (39%), Positives = 121/199 (60%), Gaps = 1/199 (0%)
 Frame = +2

Query: 1049 VHHLFTPYSLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPA 1228
            +H +    + +GLN+FDEILE +DGI+++RG+LG+++P E+V   QK  + KC  A K  
Sbjct: 215  IHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVV 274

Query: 1229 VV-TRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAE 1405
            +  T+++DSM  N RPTRAEA DVANA+LDG+DA++L  E+ +G YP+E +S +  IC  
Sbjct: 275  ITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER 334

Query: 1406 AEKVFNQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKY 1585
             ++V N  L F          +   E++   AV  A K+ A +I+  T  G++AR + KY
Sbjct: 335  TDRVMNSRLEFNND----NRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKY 390

Query: 1586 RPTMPVLSVVIPRLKTNQL 1642
             P   +L++       +QL
Sbjct: 391  FPDATILALTTNEKTAHQL 409



 Score =  117 bits (293), Expect = 3e-25
 Identities = 73/238 (30%), Positives = 129/238 (54%), Gaps = 1/238 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GPK+ S E ++  L AGM+V R +FS GD A H + ++NL+  +  T K  A+
Sbjct: 4   TKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAI 63

Query: 427 MLDTVGPELQVVN-KSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATI 603
           +LDT GPE++ +  +    +SL+  ++   T  K    +S+++ + + G    +  G T+
Sbjct: 64  LLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTV 123

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
            V   L        + +EV+ ++G+ V+C + N+  L G    ++   + I +P L+++D
Sbjct: 124 LVDDGL--------IGMEVTAIEGNKVICKVLNNGDL-GENKGVNLPGVSIALPALAEKD 174

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISRY 957
           K  +  +G    +DF++ S+ R   DV + RE L   G      I +KIEN E ++ +
Sbjct: 175 KQDL-IFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGG-ENIHIISKIENQEGLNNF 230

to top

>P0AD62:KPYK1_ECO57 Pyruvate kinase I - Escherichia coli O157:H7|
          Length = 470

 Score =  149 bits (376), Expect = 6e-35
 Identities = 78/199 (39%), Positives = 121/199 (60%), Gaps = 1/199 (0%)
 Frame = +2

Query: 1049 VHHLFTPYSLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPA 1228
            +H +    + +GLN+FDEILE +DGI+++RG+LG+++P E+V   QK  + KC  A K  
Sbjct: 215  IHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVV 274

Query: 1229 VV-TRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAE 1405
            +  T+++DSM  N RPTRAEA DVANA+LDG+DA++L  E+ +G YP+E +S +  IC  
Sbjct: 275  ITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER 334

Query: 1406 AEKVFNQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKY 1585
             ++V N  L F          +   E++   AV  A K+ A +I+  T  G++AR + KY
Sbjct: 335  TDRVMNSRLEFNND----NRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKY 390

Query: 1586 RPTMPVLSVVIPRLKTNQL 1642
             P   +L++       +QL
Sbjct: 391  FPDATILALTTNEKTAHQL 409



 Score =  117 bits (293), Expect = 3e-25
 Identities = 73/238 (30%), Positives = 129/238 (54%), Gaps = 1/238 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GPK+ S E ++  L AGM+V R +FS GD A H + ++NL+  +  T K  A+
Sbjct: 4   TKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAI 63

Query: 427 MLDTVGPELQVVN-KSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATI 603
           +LDT GPE++ +  +    +SL+  ++   T  K    +S+++ + + G    +  G T+
Sbjct: 64  LLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTV 123

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
            V   L        + +EV+ ++G+ V+C + N+  L G    ++   + I +P L+++D
Sbjct: 124 LVDDGL--------IGMEVTAIEGNKVICKVLNNGDL-GENKGVNLPGVSIALPALAEKD 174

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISRY 957
           K  +  +G    +DF++ S+ R   DV + RE L   G      I +KIEN E ++ +
Sbjct: 175 KQDL-IFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGG-ENIHIISKIENQEGLNNF 230

to top

>P34038:KPYK_LACDE Pyruvate kinase - Lactobacillus delbrueckii subsp. bulgaricus|
          Length = 589

 Score =  145 bits (367), Expect = 7e-34
 Identities = 78/183 (42%), Positives = 120/183 (65%), Gaps = 3/183 (1%)
 Frame = +2

Query: 1073 SLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVD 1249
            S +G+++ DEIL+ +DG++++RG++G+++P   V   QK+ + KCN  GKP +  T+++D
Sbjct: 224  SQEGIDNIDEILQVSDGLMVARGDMGVEIPFINVPFVQKTLIKKCNALGKPVITATQMLD 283

Query: 1250 SMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFN-- 1423
            SM +N RPTRAE TDVANAVLDG+DA +L  E+  GLYPV+++  +  I    EK  +  
Sbjct: 284  SMQENPRPTRAEVTDVANAVLDGTDATMLSGESANGLYPVQSVQAMHDIDVRTEKELDTR 343

Query: 1424 QDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPV 1603
              L  +R  +Y G  +T  E+I  S VR A ++    II  TSSG  AR+I+KYRP   +
Sbjct: 344  NTLALQRFEEYKGSNVT--EAIGESVVRTAQELGVKTIIAATSSGYTARMISKYRPDATI 401

Query: 1604 LSV 1612
            +++
Sbjct: 402  VAL 404



 Score = 90.1 bits (222), Expect = 4e-17
 Identities = 60/234 (25%), Positives = 117/234 (50%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP S  +E I+   +AG +V RF+FS G+   H   +  ++   K T KL  +
Sbjct: 4   TKIVSTLGPASDDIETITKLAEAGANVFRFNFSHGNHEEHLARMNMVREVEKKTGKLLGI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
            LDT G E++  ++     ++   + + ++    +  +  ++ + + GL      G T+ 
Sbjct: 64  ALDTKGAEIRTTDQEGGKFTINTGDEIRVSMDATKAGNKDMIHVTYPGLFDDTHVGGTVL 123

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDK 786
           +            + ++  + +  ++VC  +N+  + GS   ++   + I +P ++++D 
Sbjct: 124 I------DDGAVGLTIKAKDEEKRELVCEAQNTGVI-GSKKGVNAPGVEIRLPGITEKDT 176

Query: 787 DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D + ++G  + I+F+  S+ R A+DV   R  L +  + S   IF KIE+ E I
Sbjct: 177 DDI-RFGLKHGINFIFASFVRKAQDVLDIRA-LCEEANASYVKIFPKIESQEGI 228

to top

>Q49YC7:KPYK_STAS1 Pyruvate kinase - Staphylococcus saprophyticus subsp. saprophyticus|
            (strain ATCC 15305 / DSM 20229)
          Length = 586

 Score =  144 bits (363), Expect = 2e-33
 Identities = 79/216 (36%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++  EILE +DG++++RG++G+++PPE V + QK  + +CN  GKP +  T+++DSM
Sbjct: 225  EGIDNIKEILEVSDGLMVARGDMGVEIPPESVPMVQKDLIRQCNKLGKPVITATQMLDSM 284

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  G YP E + T+  I   AE   +    
Sbjct: 285  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGQYPEEAVKTMRNIAVSAEAAQDYKKL 344

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 345  LSDRTKLVETSL--VNAIGVSVAHTALNLNVKAIVAATESGSTARTISKYRPQSDIIAVT 402

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  +T            ARQ  +V G+FP++ + R
Sbjct: 403  -PNAET------------ARQCALVWGIFPVVKEGR 425



 Score =  100 bits (248), Expect = 4e-20
 Identities = 69/236 (29%), Positives = 121/236 (51%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E +   +KAGM+VAR +FS GD A H+  ++ ++   K   K  A+
Sbjct: 4   TKIVCTIGPASESEEMLEKLIKAGMNVARLNFSHGDQAEHKARIDTIRKVSKRLGKTVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE+   V ++  +  E + +   + +  L   V+ G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGLIELEKGSEVTVSMTE-VEGTPEKFSVTYENLINDVEEGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQ--GDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + L+V  +     +V+C + N+  L      ++   + + +P ++D+
Sbjct: 123 LDDGL--------IELQVKSIDKANGEVLCDVLNTGELKNKK-GVNLPGVKVSLPGITDK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D D +  +G    +DF++ S+ R   DV   R+ L    + + ++I  KIEN E I
Sbjct: 174 DADDI-NFGISEGVDFIAASFVRRPSDVLDIRKLLEAKQNKNISII-PKIENQEGI 227

to top

>Q8CS69:KPYK_STAES Pyruvate kinase - Staphylococcus epidermidis (strain ATCC 12228)|
          Length = 585

 Score =  144 bits (362), Expect = 3e-33
 Identities = 81/216 (37%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++ +EILE +DG++++RG++G+++PPE V + QK  + KCN  GKP +  T+++DSM
Sbjct: 224  EGIDNIEEILEVSDGLMVARGDMGVEIPPESVPMVQKDLIRKCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  G YP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGQYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGVSVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  KT            ARQ  IV G+ P++ + R
Sbjct: 402  -PSEKT------------ARQCAIVWGVNPVVKEGR 424



 Score =  103 bits (257), Expect = 4e-21
 Identities = 70/236 (29%), Positives = 123/236 (52%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E +   + AGM+VAR +FS G    H+  ++ ++   K   K   +
Sbjct: 4   TKIVCTIGPASESEEMLEKLMNAGMNVARLNFSHGSHEEHKARIDTIRKVAKRLNKTIGL 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE+ + V+++ ++  E + +   + +  L   V  G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGLIVLEKGKEVIVSMNE-VEGTPEKFSVTYENLINDVNIGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQGD--DVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        V L+V E+  D  +V C I N+  L      ++   + +++P ++D+
Sbjct: 123 LDDGL--------VELQVKEINKDKGEVKCDILNTGELKNKK-GVNLPGVKVNLPGITDK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D D + ++G    +DF++ S+ R   DV   R+ L +  + ++  IF KIEN E I
Sbjct: 174 DADDI-RFGIKENVDFIAASFVRRPSDVLDIRQILEE--EKAEITIFPKIENQEGI 226

to top

>Q5HNK7:KPYK_STAEQ Pyruvate kinase - Staphylococcus epidermidis (strain ATCC 35984 /|
            RP62A)
          Length = 585

 Score =  144 bits (362), Expect = 3e-33
 Identities = 81/216 (37%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++ +EILE +DG++++RG++G+++PPE V + QK  + KCN  GKP +  T+++DSM
Sbjct: 224  EGIDNIEEILEVSDGLMVARGDMGVEIPPESVPMVQKDLIRKCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  G YP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGQYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGVSVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  KT            ARQ  IV G+ P++ + R
Sbjct: 402  -PSEKT------------ARQCAIVWGVNPVVKEGR 424



 Score =  103 bits (257), Expect = 4e-21
 Identities = 70/236 (29%), Positives = 123/236 (52%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E +   + AGM+VAR +FS G    H+  ++ ++   K   K   +
Sbjct: 4   TKIVCTIGPASESEEMLEKLMNAGMNVARLNFSHGSHEEHKARIDTIRKVAKRLNKTIGL 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE+ + V+++ ++  E + +   + +  L   V  G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGLIVLEKGKEVIVSMNE-VEGTPEKFSVTYENLINDVNIGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQGD--DVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        V L+V E+  D  +V C I N+  L      ++   + +++P ++D+
Sbjct: 123 LDDGL--------VELQVKEINKDKGEVKCDILNTGELKNKK-GVNLPGVKVNLPGITDK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D D + ++G    +DF++ S+ R   DV   R+ L +  + ++  IF KIEN E I
Sbjct: 174 DADDI-RFGIKENVDFIAASFVRRPSDVLDIRQILEE--EKAEITIFPKIENQEGI 226

to top

>Q6GG09:KPYK_STAAR Pyruvate kinase - Staphylococcus aureus (strain MRSA252)|
          Length = 585

 Score =  143 bits (361), Expect = 3e-33
 Identities = 81/216 (37%), Positives = 125/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++ +EILE +DG++++RG++G+++PPEKV + QK  + +CN  GKP +  T+++DSM
Sbjct: 224  EGIDNIEEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  GLYP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  +T            ARQ  IV G+ P++   R
Sbjct: 402  -PSEET------------ARQCSIVWGVQPVVKKGR 424



 Score =  101 bits (251), Expect = 2e-20
 Identities = 68/236 (28%), Positives = 121/236 (51%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E I   + AGM+VAR +FS G    H+  ++ ++   K   K+ A+
Sbjct: 4   TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE    V+++ ++  E + +   + +  L   V+ G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQ--GDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + L+V ++     +V C I NS  L      ++   + + +P ++++
Sbjct: 123 LDDGL--------IELQVKDIDHAKKEVKCDILNSGELKNKK-GVNLPGVRVSLPGITEK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D + + ++G    +DF++ S+ R   DV + RE L +    +   +F KIEN E I
Sbjct: 174 DAEDI-RFGIKENVDFIAASFVRRPSDVLEIREILEE--QKANISVFPKIENQEGI 226

to top

>Q7A0N4:KPYK_STAAW Pyruvate kinase - Staphylococcus aureus (strain MW2)|
          Length = 585

 Score =  142 bits (357), Expect = 1e-32
 Identities = 81/216 (37%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++  EILE +DG++++RG++G+++PPEKV + QK  + +CN  GKP +  T+++DSM
Sbjct: 224  EGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  GLYP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  +T            ARQ  IV G+ P++   R
Sbjct: 402  -PSEET------------ARQCSIVWGVQPVVKKGR 424



 Score =  101 bits (251), Expect = 2e-20
 Identities = 68/236 (28%), Positives = 121/236 (51%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E I   + AGM+VAR +FS G    H+  ++ ++   K   K+ A+
Sbjct: 4   TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE    V+++ ++  E + +   + +  L   V+ G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQ--GDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + L+V ++     +V C I NS  L      ++   + + +P ++++
Sbjct: 123 LDDGL--------IELQVKDIDHAKKEVKCDILNSGELKNKK-GVNLPGVRVSLPGITEK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D + + ++G    +DF++ S+ R   DV + RE L +    +   +F KIEN E I
Sbjct: 174 DAEDI-RFGIKENVDFIAASFVRRPSDVLEIREILEE--QKANISVFPKIENQEGI 226

to top

>Q6G8M9:KPYK_STAAS Pyruvate kinase - Staphylococcus aureus (strain MSSA476)|
          Length = 585

 Score =  142 bits (357), Expect = 1e-32
 Identities = 81/216 (37%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++  EILE +DG++++RG++G+++PPEKV + QK  + +CN  GKP +  T+++DSM
Sbjct: 224  EGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  GLYP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  +T            ARQ  IV G+ P++   R
Sbjct: 402  -PSEET------------ARQCSIVWGVQPVVKKGR 424



 Score =  101 bits (251), Expect = 2e-20
 Identities = 68/236 (28%), Positives = 121/236 (51%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E I   + AGM+VAR +FS G    H+  ++ ++   K   K+ A+
Sbjct: 4   TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE    V+++ ++  E + +   + +  L   V+ G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQ--GDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + L+V ++     +V C I NS  L      ++   + + +P ++++
Sbjct: 123 LDDGL--------IELQVKDIDHAKKEVKCDILNSGELKNKK-GVNLPGVRVSLPGITEK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D + + ++G    +DF++ S+ R   DV + RE L +    +   +F KIEN E I
Sbjct: 174 DAEDI-RFGIKENVDFIAASFVRRPSDVLEIREILEE--QKANISVFPKIENQEGI 226

to top

>Q7A559:KPYK_STAAN Pyruvate kinase - Staphylococcus aureus (strain N315)|
          Length = 585

 Score =  142 bits (357), Expect = 1e-32
 Identities = 81/216 (37%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++  EILE +DG++++RG++G+++PPEKV + QK  + +CN  GKP +  T+++DSM
Sbjct: 224  EGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  GLYP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  +T            ARQ  IV G+ P++   R
Sbjct: 402  -PSEET------------ARQCSIVWGVQPVVKKGR 424



 Score =  101 bits (251), Expect = 2e-20
 Identities = 68/236 (28%), Positives = 121/236 (51%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E I   + AGM+VAR +FS G    H+  ++ ++   K   K+ A+
Sbjct: 4   TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE    V+++ ++  E + +   + +  L   V+ G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQ--GDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + L+V ++     +V C I NS  L      ++   + + +P ++++
Sbjct: 123 LDDGL--------IELQVKDIDHAKKEVKCDILNSGELKNKK-GVNLPGVRVSLPGITEK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D + + ++G    +DF++ S+ R   DV + RE L +    +   +F KIEN E I
Sbjct: 174 DAEDI-RFGIKENVDFIAASFVRRPSDVLEIREILEE--QKANISVFPKIENQEGI 226

to top

>Q99TG5:KPYK_STAAM Pyruvate kinase - Staphylococcus aureus (strain Mu50 / ATCC 700699)|
          Length = 585

 Score =  142 bits (357), Expect = 1e-32
 Identities = 81/216 (37%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++  EILE +DG++++RG++G+++PPEKV + QK  + +CN  GKP +  T+++DSM
Sbjct: 224  EGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  GLYP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  +T            ARQ  IV G+ P++   R
Sbjct: 402  -PSEET------------ARQCSIVWGVQPVVKKGR 424



 Score =  101 bits (251), Expect = 2e-20
 Identities = 68/236 (28%), Positives = 121/236 (51%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E I   + AGM+VAR +FS G    H+  ++ ++   K   K+ A+
Sbjct: 4   TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE    V+++ ++  E + +   + +  L   V+ G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQ--GDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + L+V ++     +V C I NS  L      ++   + + +P ++++
Sbjct: 123 LDDGL--------IELQVKDIDHAKKEVKCDILNSGELKNKK-GVNLPGVRVSLPGITEK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D + + ++G    +DF++ S+ R   DV + RE L +    +   +F KIEN E I
Sbjct: 174 DAEDI-RFGIKENVDFIAASFVRRPSDVLEIREILEE--QKANISVFPKIENQEGI 226

to top

>Q5HF76:KPYK_STAAC Pyruvate kinase - Staphylococcus aureus (strain COL)|
          Length = 585

 Score =  142 bits (357), Expect = 1e-32
 Identities = 81/216 (37%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++  EILE +DG++++RG++G+++PPEKV + QK  + +CN  GKP +  T+++DSM
Sbjct: 224  EGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  GLYP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  +T            ARQ  IV G+ P++   R
Sbjct: 402  -PSEET------------ARQCSIVWGVQPVVKKGR 424



 Score =  101 bits (251), Expect = 2e-20
 Identities = 68/236 (28%), Positives = 121/236 (51%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E I   + AGM+VAR +FS G    H+  ++ ++   K   K+ A+
Sbjct: 4   TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE    V+++ ++  E + +   + +  L   V+ G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQ--GDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + L+V ++     +V C I NS  L      ++   + + +P ++++
Sbjct: 123 LDDGL--------IELQVKDIDHAKKEVKCDILNSGELKNKK-GVNLPGVRVSLPGITEK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D + + ++G    +DF++ S+ R   DV + RE L +    +   +F KIEN E I
Sbjct: 174 DAEDI-RFGIKENVDFIAASFVRRPSDVLEIREILEE--QKANISVFPKIENQEGI 226

to top

>Q2YTE3:KPYK_STAAB Pyruvate kinase - Staphylococcus aureus (strain bovine RF122)|
          Length = 585

 Score =  142 bits (357), Expect = 1e-32
 Identities = 81/216 (37%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++  EILE +DG++++RG++G+++PPEKV + QK  + +CN  GKP +  T+++DSM
Sbjct: 224  EGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  GLYP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  +T            ARQ  IV G+ P++   R
Sbjct: 402  -PSEET------------ARQCSIVWGVQPVVKKGR 424



 Score =  101 bits (251), Expect = 2e-20
 Identities = 68/236 (28%), Positives = 121/236 (51%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E I   + AGM+VAR +FS G    H+  ++ ++   K   K+ A+
Sbjct: 4   TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE    V+++ ++  E + +   + +  L   V+ G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQ--GDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + L+V ++     +V C I NS  L      ++   + + +P ++++
Sbjct: 123 LDDGL--------IELQVKDIDHAKKEVKCDILNSGELKNKK-GVNLPGVRVSLPGITEK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D + + ++G    +DF++ S+ R   DV + RE L +    +   +F KIEN E I
Sbjct: 174 DAEDI-RFGIKENVDFIAASFVRRPSDVLEIREILEE--QKANISVFPKIENQEGI 226

to top

>Q2FXM9:KPYK_STAA8 Pyruvate kinase - Staphylococcus aureus (strain NCTC 8325)|
          Length = 585

 Score =  142 bits (357), Expect = 1e-32
 Identities = 81/216 (37%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++  EILE +DG++++RG++G+++PPEKV + QK  + +CN  GKP +  T+++DSM
Sbjct: 224  EGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  GLYP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  +T            ARQ  IV G+ P++   R
Sbjct: 402  -PSEET------------ARQCSIVWGVQPVVKKGR 424



 Score =  101 bits (251), Expect = 2e-20
 Identities = 68/236 (28%), Positives = 121/236 (51%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E I   + AGM+VAR +FS G    H+  ++ ++   K   K+ A+
Sbjct: 4   TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE    V+++ ++  E + +   + +  L   V+ G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQ--GDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + L+V ++     +V C I NS  L      ++   + + +P ++++
Sbjct: 123 LDDGL--------IELQVKDIDHAKKEVKCDILNSGELKNKK-GVNLPGVRVSLPGITEK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D + + ++G    +DF++ S+ R   DV + RE L +    +   +F KIEN E I
Sbjct: 174 DAEDI-RFGIKENVDFIAASFVRRPSDVLEIREILEE--QKANISVFPKIENQEGI 226

to top

>Q2FG40:KPYK_STAA3 Pyruvate kinase - Staphylococcus aureus (strain USA300)|
          Length = 585

 Score =  142 bits (357), Expect = 1e-32
 Identities = 81/216 (37%), Positives = 124/216 (57%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++  EILE +DG++++RG++G+++PPEKV + QK  + +CN  GKP +  T+++DSM
Sbjct: 224  EGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSM 283

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  GLYP E + T+  I   AE   +    
Sbjct: 284  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKL 343

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  AR I+KYRP   +++V 
Sbjct: 344  LSDRTKLVETSL--VNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVT 401

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
             P  +T            ARQ  IV G+ P++   R
Sbjct: 402  -PSEET------------ARQCSIVWGVQPVVKKGR 424



 Score =  101 bits (251), Expect = 2e-20
 Identities = 68/236 (28%), Positives = 121/236 (51%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E I   + AGM+VAR +FS G    H+  ++ ++   K   K+ A+
Sbjct: 4   TKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  N  +  I LE    V+++ ++  E + +   + +  L   V+ G+ I 
Sbjct: 64  LLDTKGPEIRTHNMKDGIIELERGNEVIVSMNE-VEGTPEKFSVTYENLINDVQVGSYIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQ--GDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +   L        + L+V ++     +V C I NS  L      ++   + + +P ++++
Sbjct: 123 LDDGL--------IELQVKDIDHAKKEVKCDILNSGELKNKK-GVNLPGVRVSLPGITEK 173

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D + + ++G    +DF++ S+ R   DV + RE L +    +   +F KIEN E I
Sbjct: 174 DAEDI-RFGIKENVDFIAASFVRRPSDVLEIREILEE--QKANISVFPKIENQEGI 226

to top

>Q4L739:KPYK_STAHJ Pyruvate kinase - Staphylococcus haemolyticus (strain JCSC1435)|
          Length = 586

 Score =  140 bits (353), Expect = 3e-32
 Identities = 77/216 (35%), Positives = 120/216 (55%), Gaps = 1/216 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++ +EILE +DG++++RG++G+++PPE V + QK  + KCN  GKP +  T+++DSM
Sbjct: 225  EGIDNIEEILEVSDGLMVARGDMGVEIPPESVPIVQKDLIRKCNKLGKPVITATQMLDSM 284

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N R TRAEA+DVANA+ DG+DA++L  ET  GLYP E + T+  I   AE   +    
Sbjct: 285  QRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKL 344

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
                 K V   +  + +I  S    A+ +    I+  T SG  A  I+KYRP   +++V 
Sbjct: 345  LSDRTKLVETSL--VNAIGVSVAHTALNLNVKAIVAATESGSTAVTISKYRPHSDIIAVT 402

Query: 1616 IPRLKTNQLKWSFTGAFEARQSLIVRGLFPMLADPR 1723
                              ARQ  +V G +P++   R
Sbjct: 403  -------------PSEHTARQLALVWGAYPVIKKGR 425



 Score = 95.1 bits (235), Expect = 1e-18
 Identities = 65/234 (27%), Positives = 118/234 (50%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E +   +KAGM+VAR +FS G    H+  ++ ++       K   +
Sbjct: 4   TKIVCTIGPASESEEMLEKLMKAGMNVARLNFSHGSHEEHKARIDTIRKVADRLGKTIGI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LDT GPE++  +  +  I LE+ + V+++  +  E + +   + +  L   V+      
Sbjct: 64  LLDTKGPEIRTHDMKDGLIMLEKGKEVIVSMSQ-VEGTPEKFSVTYEDLINDVQ------ 116

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDK 786
           VG Y+        + ++  +    +V C I N+  L      ++   + +++P ++D+D 
Sbjct: 117 VGSYILLDDGLVELQVKDIDKTKGEVKCDILNTGELKNKK-GVNLPGVKVNLPGITDKDA 175

Query: 787 DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D +  +G    +D+++ S+ R   DV   RE L +  + + T IF KIEN E I
Sbjct: 176 DDI-LFGIKEDVDYIAASFVRRPSDVLDIREILERENNHNIT-IFPKIENQEGI 227

to top

>Q46289:KPYK_CLOPE Pyruvate kinase - Clostridium perfringens|
          Length = 474

 Score =  139 bits (350), Expect = 6e-32
 Identities = 66/181 (36%), Positives = 116/181 (64%), Gaps = 1/181 (0%)
 Frame = +2

Query: 1073 SLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVD 1249
            S +G+++  EI++  DG++++RG++G+++P E V + QK+ + KCN AGK  +  T+++D
Sbjct: 222  SQEGVDNIKEIIKVTDGVMVARGDMGVEIPIENVPIIQKNIIKKCNQAGKIVITATQMLD 281

Query: 1250 SMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQD 1429
            SM  N RPTRAEA+DV NA+ DG+DAI+L  E+  G +P+E   T+ RI  +AE   + +
Sbjct: 282  SMIRNPRPTRAEASDVCNAIFDGTDAIMLSGESASGSFPIEAAMTMSRIAKKAEANLDYN 341

Query: 1430 LYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLS 1609
               +R       P    ++I+ SA + A K     I+  T +G  A++++KY+P+ P+++
Sbjct: 342  YLLRRLKDPNPNPDAFADAISYSASKTASKFPTKAIVAATQTGSTAKILSKYKPSCPIIA 401

Query: 1610 V 1612
            +
Sbjct: 402  I 402



 Score = 99.8 bits (247), Expect = 5e-20
 Identities = 65/232 (28%), Positives = 115/232 (49%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TK++ T+GP S S E +   ++ GM+ AR +FS GD A H+E +E +K   K  K   A+
Sbjct: 4   TKMIFTIGPSSDSEEILREFIRIGMNAARLNFSHGDHASHKEKIELIKRLRKEEKSATAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           +LD  GP+++  N       L+  +    +        +    I++  L + +KPG +I 
Sbjct: 64  LLDIKGPKIRTYNFKNGEAELKNGDEFTFSCGDEILGDNTKCSISYKELYEDIKPGGSIL 123

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDK 786
           V   L           +V EV+G D++C +    T+      ++   + I +P ++++D+
Sbjct: 124 VDDGLLE--------FKVKEVRGTDIICEVIEGGTIKDHK-GVNVPNVPIKLPAVTEKDR 174

Query: 787 DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVE 942
             +  +G   ++DF++ S+ R  EDV + RE L   G      I +KIE+ E
Sbjct: 175 SDL-IFGCEMEVDFVAASFIRKPEDVLEVREILDSHGG-KDIKIISKIESQE 224

to top

>O30853:KPYK1_PHOLE Pyruvate kinase I - Photobacterium leiognathi|
          Length = 235

 Score =  133 bits (334), Expect = 4e-30
 Identities = 74/203 (36%), Positives = 120/203 (59%), Gaps = 2/203 (0%)
 Frame = +2

Query: 1115 ADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMTDNLRPTRAEAT 1291
            +DGI+++RG+LG+++P E+V   QK  + KCN A K  +  T+++DSM  N RPTRAEA 
Sbjct: 2    SDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAG 61

Query: 1292 DVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKRTVKYVGEPM 1471
            DVANA++DG+DA++L  E+ +G YP+E ++ + +ICA  + V   +L  +     +  P 
Sbjct: 62   DVANAIMDGTDAVMLSGESAKGKYPIEAVTIMAQICARTDDVVKPELGSR-----LDSPR 116

Query: 1472 THL-ESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKW 1648
              + E++   AV  A K+ A +II  T +G++AR + KY PT  +L+V            
Sbjct: 117  LRITEAVCKGAVDTAEKLNAPLIIVATEAGKSARSVRKYFPTARILAVT----------- 165

Query: 1649 SFTGAFEARQSLIVRGLFPMLAD 1717
              T    A Q  + +G+ P++ D
Sbjct: 166  --TNTKTAAQLCLSKGVTPVVVD 186

to top

>P70789:KPYK1_AGRVI Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)|
          Length = 474

 Score =  132 bits (333), Expect = 6e-30
 Identities = 74/190 (38%), Positives = 116/190 (61%), Gaps = 4/190 (2%)
 Frame = +2

Query: 1085 LNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMTD 1261
            L+  D+I+  +D I+++RG+LG+++PPE V   QK  +  C +A KP +V T+++DSM  
Sbjct: 227  LDEIDDIVALSDAIMVARGDLGVEIPPEDVPGRQKELIRACRIAAKPVIVATQMLDSMVT 286

Query: 1262 NLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFK 1441
            +  PTRAEA+DVA A+ DG+DA++L AE+  G +PVET+  + RI  + EK       F 
Sbjct: 287  SPTPTRAEASDVAGAIYDGADAVMLSAESATGAFPVETVEIMSRIIEKTEK-----HKFY 341

Query: 1442 RTVKYVGEPM---THLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            R +    EP    T   ++A++A   A+ +KA VI+ FT SG  A  I++ RP +P+L++
Sbjct: 342  RPILEATEPQIAHTPPHAVATAAADVALALKAPVIVAFTVSGTTASRISRARPPLPILAL 401

Query: 1613 VIPRLKTNQL 1642
                    QL
Sbjct: 402  TPSEQTARQL 411



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 47/230 (20%), Positives = 97/230 (42%), Gaps = 2/230 (0%)
 Frame = +1

Query: 250 KIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAVM 429
           KIV T+GP S S   + +   AG+   R +FS G    H     +++   K       ++
Sbjct: 10  KIVATVGPASSSPAILRSLFLAGVDTFRLNFSHGSRDDHAAAYRHIRALEKELGTSIGIL 69

Query: 430 LDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIFV 609
            D  GP++++    E  + L ++  +              +P+    +  AVKPG  + +
Sbjct: 70  QDLQGPKIRIGVLHEGRLQLTKDAEIRFVCGTEPGRGLMDIPLPHREIFAAVKPGDDLLI 129

Query: 610 --GQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
             G+        +  +++   +    +    +    L G++         +D+  L+ +D
Sbjct: 130 DDGRVRVRALGVSDEFIDAKVIVAGPI--SNRKGVNLPGTV---------LDISPLTPKD 178

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIE 933
           +  + ++G    +D+++LS+ + A D+ +AR  +S    L      AKIE
Sbjct: 179 RKDL-EFGLELGVDWIALSFVQTARDMIEARSLVSDRAGL-----IAKIE 222

to top

>Q44473:KPYK2_AGRVI Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)|
          Length = 482

 Score =  131 bits (329), Expect = 2e-29
 Identities = 66/177 (37%), Positives = 113/177 (63%), Gaps = 1/177 (0%)
 Frame = +2

Query: 1085 LNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMTD 1261
            L+  ++I+  +D ++++RG+LG+++PPE V   QK  +  C +A KP +V T+++DSM  
Sbjct: 227  LDDIEDIVRLSDSVMVARGDLGVEIPPEDVPGKQKEIIRACRLAAKPVIVATQMLDSMVS 286

Query: 1262 NLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFK 1441
            +  PTRAEA+DVA A+ DG+DA++L AET  G YPVE +  + RI  + EK  +     +
Sbjct: 287  SPTPTRAEASDVAGAIYDGADAVMLSAETATGAYPVEAVEIMNRIIEKTEKHKHYRPILE 346

Query: 1442 RTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
             T   V +   H  ++A++A   A+ + + V++ +TSSG  A  I++ RP +P+L++
Sbjct: 347  ATEPDVAQSPPH--AVATAAANVAVALGSPVVVAYTSSGTTAARISRARPALPILAL 401



 Score = 63.2 bits (152), Expect = 6e-09
 Identities = 51/243 (20%), Positives = 117/243 (48%), Gaps = 2/243 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           +KIV T+GP S S + + +   AG+   R +FS G  A H E   N++   +      AV
Sbjct: 9   SKIVATVGPASSSPDMLRSLFLAGVDTFRLNFSHGARADHAEVYRNIRALEQEHDAAIAV 68

Query: 427 MLDTVGPELQVVNKSEVTISLEENESV-VLTPHKGQEASSKLLPINFSGLAKAVKPGATI 603
           + D  GP++++   +   + L    ++  +   +G E  +  +P+    + +   PG  +
Sbjct: 69  LQDLQGPKIRIGVLAHGRLDLARGSTIGFILGREGGEGMND-IPLPHREIFEVAVPGMDL 127

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
            +        +   + + + EV    +VC + N   L+     ++     +D+  L+ +D
Sbjct: 128 LI--------DDGRIKVRIMEVMDGRLVCEVLNGGALSNRK-GVNVPGAVLDISPLTAKD 178

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFL-SKLGDLSQTLIFAKIENVEVISRYS 960
           ++ + ++G    +D+++LS+ + A D+ +AR  +  + G +++    + ++++E I R S
Sbjct: 179 REDL-EFGLELGVDWVALSFVQRARDMIEARSLVGDRAGLIAKIEKPSALDDIEDIVRLS 237

Query: 961 FNI 969
            ++
Sbjct: 238 DSV 240

to top

>Q07637:KPYK_LACLA Pyruvate kinase - Lactococcus lactis subsp. lactis (Streptococcus|
            lactis)
          Length = 502

 Score =  127 bits (318), Expect = 3e-28
 Identities = 70/179 (39%), Positives = 111/179 (62%), Gaps = 1/179 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            QG+ + DEI+E ADGI+++RG++GI++P E V ++QK  + K N AGK  V  T +++SM
Sbjct: 255  QGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIVVTATNMLESM 314

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
            T N R TR+E +DV NAV+DG+DA +L  E+  G YP E++ T+  +   A+ +  +   
Sbjct: 315  TYNPRATRSEISDVFNAVIDGTDATMLSGESANGKYPRESVRTMATVNKNAQTMLKE--- 371

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            + R      +  T  E +A+S   AA  +   +I+  T SG  ARLI+K+RP   +L++
Sbjct: 372  YGRLHPERYDKSTVTEVVAASVKNAAEAMDIKLIVALTESGNTARLISKHRPNADILAI 430

to top

>Q9PK61:KPYK_CHLMU Pyruvate kinase - Chlamydia muridarum|
          Length = 481

 Score =  123 bits (309), Expect = 4e-27
 Identities = 66/179 (36%), Positives = 109/179 (60%), Gaps = 2/179 (1%)
 Frame = +2

Query: 1082 GLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMT 1258
            G+ +F EI + +DGI+++RG+LGI+L   +V   QK         G+  +  T++++SM 
Sbjct: 225  GVQNFQEIAKASDGIMIARGDLGIELSIVEVPALQKFMARVSRETGRFCITATQMLESMI 284

Query: 1259 DNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYF 1438
             N  PTRAE +DVANA+ DG+ A++L  ET  G YP+E + T+  I  E EK F+   +F
Sbjct: 285  RNPLPTRAEVSDVANAIHDGTSAVMLSGETASGTYPIEAVKTMRSIIQETEKSFDYQAFF 344

Query: 1439 KRTVKYVGEPMT-HLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            +   K     ++ +LE+I +S ++ A K  A  II +T +G +   ++KYRP +P+++V
Sbjct: 345  QLNDKNSALKVSPYLEAIGASGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAV 403



 Score = 75.5 bits (184), Expect = 1e-12
 Identities = 65/235 (27%), Positives = 114/235 (48%), Gaps = 3/235 (1%)
 Frame = +1

Query: 241 AMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLC 420
           A TKI+ T+GP + + E +   L AGM+VAR +FS G    H  T+  LK   +  +   
Sbjct: 3   ARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPL 62

Query: 421 AVMLDTVGPELQVVNKSEVTISLEENESVVLTPHK---GQEASSKLLPINFSGLAKAVKP 591
           A+MLDT GPE++ + + E  I ++  + + LT  +    +EA   L P   S +   V+ 
Sbjct: 63  AIMLDTKGPEIR-LGQVESPIKVKPGDRLTLTSKEILGSKEAGVTLYP---SCVFPFVRE 118

Query: 592 GATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTL 771
            A + +        +   +   V   Q   +    +NS  +  +  +L    I + +P +
Sbjct: 119 RAPVLI--------DDGYIQAVVVNAQEHLIEIEFQNSGEIKSNK-SLSIKDIDVALPFM 169

Query: 772 SDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIEN 936
           +++D   + K+G   ++D ++ S+ R  ED+   R+ L   G  +  +I AKIEN
Sbjct: 170 TEKDITDL-KFGVEQELDLIAASFVRCNEDIDSMRKVLENFGRPNMPII-AKIEN 222

to top

>Q9WY51:KPYK_THEMA Pyruvate kinase - Thermotoga maritima|
          Length = 466

 Score =  121 bits (304), Expect = 1e-26
 Identities = 69/186 (37%), Positives = 117/186 (62%), Gaps = 1/186 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            + L   +EI++ +DGI+++RG+LG+++P E+V + QK  +       KP +V T++++SM
Sbjct: 222  KALERLEEIIKVSDGIMVARGDLGVEIPIEEVPIVQKEIIKLSKYYSKPVIVATQILESM 281

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
             +N  PTRAE TD+ANA+ DG+DA+LL AET  G +P+E I  + ++  EAEK     L 
Sbjct: 282  IENPFPTRAEVTDIANAIFDGADALLLTAETAVGKHPLEAIKVLSKVAKEAEK----KLE 337

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSVV 1615
            F RT++Y    ++  E+I+ +  + +  + A +II  T SG  A  ++KY  + P++++ 
Sbjct: 338  FFRTIEYDTSDIS--EAISHACWQLSESLNAKLIITPTISGSTAVRVSKYNVSQPIVALT 395

Query: 1616 IPRLKT 1633
             P  KT
Sbjct: 396  -PEEKT 400



 Score = 84.7 bits (208), Expect = 2e-15
 Identities = 63/236 (26%), Positives = 117/236 (49%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP++ S E I   +  G++V R + S GD    ++ +  +K   +  KK  A+
Sbjct: 4   TKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLREKKKKPVAI 63

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           ++D  GP+++     +  + L+E +   LT  K    +  ++ +N S L K VK G TI 
Sbjct: 64  LIDLAGPKIRTGYLEKEFVELKEGQIFTLTT-KEILGNEHIVSVNLSSLPKDVKKGDTIL 122

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDK 786
           +            + LEV E    +V  V+K    +      ++     + + +++D D+
Sbjct: 123 LSD--------GEIVLEVIETTDTEVKTVVKVGGKITHRR-GVNVPTADLSVESITDRDR 173

Query: 787 DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
           + + K G  + ++F +LS+ R  EDV +A+E + K G   +  + +KIE  + + R
Sbjct: 174 EFI-KLGTLHDVEFFALSFVRKPEDVLKAKEEIRKHG--KEIPVISKIETKKALER 226

to top

>P73534:KPYK2_SYNY3 Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803)|
          Length = 591

 Score =  121 bits (303), Expect = 2e-26
 Identities = 66/180 (36%), Positives = 111/180 (61%), Gaps = 2/180 (1%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            + +     +LE+ DG++++RG+LG++LP E V + QK  +   N  G P +  T+++DSM
Sbjct: 232  EAIKDMQAVLEKCDGVMVARGDLGVELPAEDVPILQKKLIATANRLGIPVITATQMLDSM 291

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
             ++ RPTRAE +DVANA+LDG+DA++L  ET  G +PVE ++ + +I   AE++  +D+ 
Sbjct: 292  VNSPRPTRAEVSDVANAILDGTDAVMLSNETAIGKFPVEAVAIMAKI---AERIEQEDI- 347

Query: 1436 FKRTVKYVGEPMTHLESIASSAV-RAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
                        T + +  SSAV + A  + A+ I+  T +G  AR ++K+RP  P+L+V
Sbjct: 348  ---NPSQAEASRTSIPNAISSAVSQIAETLNAAAIMSLTKTGSTARHVSKFRPKTPILAV 404



 Score = 77.4 bits (189), Expect = 3e-13
 Identities = 57/239 (23%), Positives = 117/239 (48%), Gaps = 2/239 (0%)
 Frame = +1

Query: 238 PAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKL 417
           P  TKIV T+GP ++S E +   ++AG +  R +FS GD AYHQ+++  ++       + 
Sbjct: 7   PRRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQIAFELNQP 66

Query: 418 CAVMLDTVGPELQVVN--KSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKP 591
             ++ D  GP+++V        ++ L+  +   LT  +  E +  +  I++  LA  V  
Sbjct: 67  VGILQDLQGPKIRVGKFLNDAGSVQLKNGDPYTLT-SRPVECTETISSISYEYLADEVPS 125

Query: 592 GATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTL 771
           GA I +            + +E  +    D+ C +    TL+ +   ++   + + +  +
Sbjct: 126 GARILL------DDGKLEMLVEEVDTVARDLHCRVIVGGTLSSNK-GVNFPGVCLSVKAM 178

Query: 772 SDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           +D+DK+ +  +G    +D+++LS+ R+ +D+ + +  ++  G      + AKIE  E I
Sbjct: 179 TDKDKEDL-MFGLDQGVDWVALSFVRNPQDIDEIKGLIAAAG--KSVPVIAKIEKHEAI 234

to top

>P94685:KPYK_CHLTR Pyruvate kinase - Chlamydia trachomatis|
          Length = 485

 Score =  119 bits (299), Expect = 5e-26
 Identities = 66/179 (36%), Positives = 106/179 (59%), Gaps = 2/179 (1%)
 Frame = +2

Query: 1082 GLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMT 1258
            G+ +F EI   ADGI+++RG+LGI+L   +V   QK         G+  +  T++++SM 
Sbjct: 225  GVQNFQEIARAADGIMIARGDLGIELSIVEVPGLQKFMARASRETGRFCITATQMLESMI 284

Query: 1259 DNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYF 1438
             N  PTRAE +DVANA+ DG+ A++L  ET  G +PV  + T+  I  E EK F+   +F
Sbjct: 285  RNPLPTRAEVSDVANAIYDGTSAVMLSGETALGAHPVHAVKTMRSIIQETEKTFDYHAFF 344

Query: 1439 KRTVKYVGEPMT-HLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            +   K     ++ +LE+I  S ++ A K  A  II +T +G +   ++KYRP +P+++V
Sbjct: 345  QLNDKNSALKVSPYLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAV 403



 Score = 73.2 bits (178), Expect = 5e-12
 Identities = 64/235 (27%), Positives = 113/235 (48%), Gaps = 3/235 (1%)
 Frame = +1

Query: 241 AMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLC 420
           A TKI+ T+GP + + E +   L AGM+VAR +FS G    H  T+  LK   +  +   
Sbjct: 3   ARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPL 62

Query: 421 AVMLDTVGPELQVVNKSEVTISLEENESVVLTPHK---GQEASSKLLPINFSGLAKAVKP 591
           A+MLDT GPE++ + + E  I ++  + + L   +    +E+   L P   S +   V+ 
Sbjct: 63  AIMLDTKGPEIR-LGQVESPIKVQPGDRLTLVSKEILGSKESGVTLYP---SCVFPYVRE 118

Query: 592 GATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTL 771
            A + +        +   +   V   Q   V    +NS  +  +  +L    I + +P +
Sbjct: 119 RAPVLI--------DDGYIQAVVVNAQEHMVEIEFQNSGEIKSNK-SLSIKDIDVALPFM 169

Query: 772 SDEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIEN 936
           +++D   + K+G   ++D ++ S+ R  ED+   R+ L   G  +  +I AKIEN
Sbjct: 170 TEKDIADL-KFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRPNMPII-AKIEN 222

to top

>Q55863:KPYK1_SYNY3 Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803)|
          Length = 483

 Score =  116 bits (291), Expect = 4e-25
 Identities = 65/178 (36%), Positives = 110/178 (61%), Gaps = 1/178 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            Q +++ +EI+  ++GI+++RG+LG+++ PEKV   QK  + +CN+   P +  T+++DSM
Sbjct: 238  QAIDNLEEIVAVSNGIMVARGDLGVEVNPEKVPRLQKEIIRRCNVRAIPVITATQMLDSM 297

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              N RPTRAEA+DVANA+LDG+DA++L  E+  G YPV+++  + +I  E E      L+
Sbjct: 298  IQNSRPTRAEASDVANAILDGTDAVMLSGESAVGQYPVKSVQMLRKIAEETE----VGLH 353

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLS 1609
                   +    TH  S A   +   + +K   I+ FT+SG  + L +  RP++PV++
Sbjct: 354  LVNNPP-IENTETHALSEALVVIDGILDLK--YIVTFTTSGFTSLLASNQRPSVPVIA 408



 Score = 87.0 bits (214), Expect = 4e-16
 Identities = 66/234 (28%), Positives = 113/234 (48%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S SVE I   + AGM+VAR +FS G    H   +  L+   +       +
Sbjct: 18  TKIVATIGPASSSVEVIRQMVDAGMNVARLNFSHGSYEDHATMVRLLRSVEQEMDTPITL 77

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           + D  GP++++         L E E V L P +  +     + I++  LA   K G  I 
Sbjct: 78  LQDLQGPKIRIGQLPGGEKQLREGEKVSLVPVEIGDRHPGAVGIDYPHLATEAKVGERIL 137

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDK 786
           +   L          ++V  +Q  +V+C +     L  S   ++   + + +P+++ +DK
Sbjct: 138 LDDGLLE--------MKVVSIQDPEVICEVVTGGILK-SRKGVNLPGLVLTLPSMTTKDK 188

Query: 787 DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
             + ++G    ID++SLS+ R  ED+   ++FL++ G     +I AKIE  + I
Sbjct: 189 QDL-EFGLSQGIDWVSLSFVRKGEDIHTLKQFLAERGHPDLPVI-AKIEKPQAI 240

to top

>O06134:KPYK_MYCTU Pyruvate kinase - Mycobacterium tuberculosis|
          Length = 472

 Score =  113 bits (282), Expect = 5e-24
 Identities = 67/184 (36%), Positives = 106/184 (57%), Gaps = 7/184 (3%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            + +++ + I+   D ++++RG+LG++LP E+V L QK A+       KP +V T+++DSM
Sbjct: 223  EAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSM 282

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGR-ICAEAEKVFNQDL 1432
             +N RPTRAEA+DVANAVLDG+DA++L  ET  G YP+  + T+ R ICA  E       
Sbjct: 283  IENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEEN------ 336

Query: 1433 YFKRTVKYVGEPMTHL----ESIASSAVR-AAIKVKASVIICFTSSGRAARLIAKYRPTM 1597
                       P+TH+      + S A R    ++ A  ++ FT SG   R +A+    +
Sbjct: 337  ------STAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPL 390

Query: 1598 PVLS 1609
            P+L+
Sbjct: 391  PLLA 394



 Score = 85.1 bits (209), Expect = 1e-15
 Identities = 64/233 (27%), Positives = 113/233 (48%)
 Frame = +1

Query: 250 KIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAVM 429
           KIV TLGP ++  + + A ++AGM VAR +FS GD   H+   E +++A  AT +   V+
Sbjct: 6   KIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVL 65

Query: 430 LDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIFV 609
            D  GP++++   +       E E+V +T     E S   +   +  LA+    G  + V
Sbjct: 66  ADLQGPKIRLGRFASGATHWAEGETVRITV-GACEGSHDRVSTTYKRLAQDAVAGDRVLV 124

Query: 610 GQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDKD 789
                   +   V L V  V+GDDVVC +     ++ +   +    +++  P LS++D +
Sbjct: 125 --------DDGKVALVVDAVEGDDVVCTVVEGGPVSDNK-GISLPGMNVTAPALSEKDIE 175

Query: 790 VMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
            +  +     +D ++LS+ R   DV    E + ++G   +  + AK+E  E I
Sbjct: 176 DL-TFALNLGVDMVALSFVRSPADVELVHEVMDRIG--RRVPVIAKLEKPEAI 225

to top

>O05118:KPYK_METEX Pyruvate kinase - Methylobacterium extorquens (Protomonas extorquens)|
          Length = 483

 Score =  112 bits (281), Expect = 6e-24
 Identities = 71/190 (37%), Positives = 111/190 (58%), Gaps = 2/190 (1%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            Q L   DEI+E +DGI+++RG+LG+++P E+V   QK         GKP VV T++++SM
Sbjct: 227  QALTRLDEIIEISDGIMVARGDLGVEMPLEQVPGVQKRITRVARRLGKPVVVATQMLESM 286

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
              +  PTRAE +DVA AV +G+DA++L AE+  G +PVE I T+ RI   AE+V    LY
Sbjct: 287  ITSPVPTRAEVSDVATAVYEGADAVMLSAESAAGDFPVEAIGTMNRI---AEQVERDALY 343

Query: 1436 FKRTVKYVGEP-MTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            +   +    EP  T  ++IA++A +    +    I+ +T SG     +A+ RP   V+++
Sbjct: 344  WSILMAQRSEPEPTASDAIAAAAHQIVEALSLRSIMAWTHSGSTVLRLARARPNASVIAL 403

Query: 1613 VIPRLKTNQL 1642
               R    +L
Sbjct: 404  TPKRETARRL 413



 Score = 49.3 bits (116), Expect = 8e-05
 Identities = 49/236 (20%), Positives = 104/236 (44%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP S + E I     AG  V R + S        E +E ++   +  K+   +
Sbjct: 12  TKIVATLGPASDTPEMIEKLFHAGADVFRINMSHLAREKLPERIEVIRTIEREGKRPIGI 71

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           ++D  GP+L++         LE  ++ VL        + ++  +    +  A++P   I 
Sbjct: 72  LVDLQGPKLRLGTFVGDAAVLENGQTFVLDSDPTPGDTDRVF-LPHPEILSALEPSHGIL 130

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDK 786
           +        +   + L V+EV     V  ++    ++     +      + +P ++++D+
Sbjct: 131 I--------DDGKLRLIVTEVSEGRAVTRVEVGGRISNRK-GVSLPHTALPVPAMTEKDR 181

Query: 787 DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
             ++  G     D++++S+ +  EDV + ++  +      + L+ AKIE  + ++R
Sbjct: 182 GDLEA-GLAAGADWIAVSFVQRPEDVAEVKKVAA-----GRALVMAKIEKPQALTR 231

to top

>P94939:KPYK_MYCIT Pyruvate kinase - Mycobacterium intracellulare|
          Length = 472

 Score =  110 bits (276), Expect = 2e-23
 Identities = 65/183 (35%), Positives = 104/183 (56%), Gaps = 6/183 (3%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            + +++ + I+   D I+++RG+LG++LP E+V L QK A+       KP +V T+++DSM
Sbjct: 223  EAVDNLETIVLAFDAIMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSM 282

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
             +N RPTRAEA+DVANAVLDG+DA++L  ET  G YP+  + T+ RI    E        
Sbjct: 283  IENSRPTRAEASDVANAVLDGADAVMLSGETSVGKYPMAAVRTMSRIICAVE-------- 334

Query: 1436 FKRTVKYVGEPMTHL----ESIASSAVR-AAIKVKASVIICFTSSGRAARLIAKYRPTMP 1600
                      P+TH+      + S A R    ++ A  ++ FT SG   + +A+    +P
Sbjct: 335  ---DNSTAAPPLTHVPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVKRLARLHTPLP 391

Query: 1601 VLS 1609
            +L+
Sbjct: 392  LLA 394



 Score = 87.8 bits (216), Expect = 2e-16
 Identities = 64/233 (27%), Positives = 114/233 (48%)
 Frame = +1

Query: 250 KIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAVM 429
           KIV TLGP + S E I A ++AGM VAR +FS GD A H+   E +++A  AT +   V+
Sbjct: 6   KIVCTLGPATNSDELILALVEAGMDVARLNFSHGDYADHKAAYERVRVASDATGRAVGVL 65

Query: 430 LDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIFV 609
            D  GP++++   +       + E+V +T     E S   +   +  LA+    G  + V
Sbjct: 66  ADLQGPKIRLGRFATGPTYWADGETVRITV-ADCEGSHDRVSTTYKKLAEDAAVGDRVLV 124

Query: 610 GQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDKD 789
                   +   V L V  ++GDDV+C +     ++ +   +    +++  P LS++D +
Sbjct: 125 --------DDGKVCLVVDGIEGDDVICTVVEGGPVSNNK-GISLPGMNVSAPALSEKDIE 175

Query: 790 VMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
            +  +     +D ++LS+ R   DV    E + ++G   +  + AK+E  E +
Sbjct: 176 DL-TFALDLGVDLVALSFVRSPADVELVHEVMDRVG--RRVPVIAKLEKPEAV 225

to top

>Q57572:KPYK_METJA Pyruvate kinase - Methanococcus jannaschii|
          Length = 447

 Score =  109 bits (272), Expect = 7e-23
 Identities = 66/197 (33%), Positives = 110/197 (55%), Gaps = 7/197 (3%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +GL +  EI  E+DG++++RG+LG+++P E + + QK+ L   N  G  ++  T+++DSM
Sbjct: 206  EGLKNIKEIARESDGVMVARGDLGVEVPIENIPIEQKNILRIANRYGILSITATQILDSM 265

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
             +N  PTRAE TD+ANA+ DG+D ++L  ET  G YP+E I  + ++   A++ + +   
Sbjct: 266  INNPFPTRAEVTDIANAIYDGTDCLMLSNETTIGKYPIEAIKVLNKVAKVADEHYEE--- 322

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAI----KVKASVIICFTSSGRAARLIAKYRPTMPV 1603
                  +       +ESI    V A      K+   ++I  T SGR A+LI+K R    +
Sbjct: 323  ------FGDRVCLEVESIDEGLVYAVYELYKKLNTKLVITPTYSGRTAKLISKLRINSKI 376

Query: 1604 LSVV--IPRLKTNQLKW 1648
            ++    I  LK  +L W
Sbjct: 377  IAPTPNIRTLKRLRLVW 393

to top

>P32044:KPYK_THEAC Pyruvate kinase - Thermoplasma acidophilum|
          Length = 544

 Score =  108 bits (271), Expect = 9e-23
 Identities = 63/195 (32%), Positives = 111/195 (56%), Gaps = 4/195 (2%)
 Frame = +2

Query: 1082 GLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMT 1258
            GL++ +EI++ +DGI+++RG+LG++LP ++V L QK  +   +  G   +V T+V++SM 
Sbjct: 208  GLDNIEEIVKSSDGIMVARGDLGVELPLKEVVLAQKHIIKTAHEDGDFTIVATQVLESMV 267

Query: 1259 DNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRIC--AEAEKVFNQDL 1432
            +N  PTRAE +D+ NA++D +DA++L  E+  G YPV+ + T+  +    E +  F+   
Sbjct: 268  NNSSPTRAEISDITNAIIDNADALMLSEESAIGKYPVQAVRTLKEVSDYVEDKVSFDSSY 327

Query: 1433 YFK-RTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLS 1609
            YFK  T+ Y         S+A +A   +  +K+  I+  T +G   R+I+  RP   V +
Sbjct: 328  YFKGNTIAY---------SVARAAKILSDDIKSDGIVALTHTGSTVRMISSLRPKAMVYA 378

Query: 1610 VVIPRLKTNQLKWSF 1654
              +      +L   F
Sbjct: 379  ATVSESLARKLNIYF 393



 Score = 56.6 bits (135), Expect = 5e-07
 Identities = 57/249 (22%), Positives = 110/249 (44%), Gaps = 8/249 (3%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP S S E +   +  G+S+ R + +  D     + +  +   +++  +   +
Sbjct: 3   TKIVATIGPASSSPEIMKQMIDNGLSLVRINSAHADI----KDVSKITQMVRSINRDVGI 58

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           M+D  GPEL+    +  T+ +   +  V+          K + +N   +  AV+ G  I 
Sbjct: 59  MIDLKGPELRTGEFAGGTLKISSGKDYVM---------GKDIVLNNMNVLSAVQVGDRIL 109

Query: 607 V--GQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           +  G+  F    T    +       +D V   ++   + G           I++ T++D 
Sbjct: 110 MSDGEVSFEVESTDPFTIRAL----NDGVLRDRSRVNIPGRF---------IELGTITDR 156

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIE------NVE 942
           D+  +++ G  + +DF +LS+ + +E+V   R+F+   G      I +KIE      N+E
Sbjct: 157 DRAFIRE-GIADGVDFFALSFVQKSENVDSLRDFVIDSG--GDQYIISKIETKSGLDNIE 213

Query: 943 VISRYSFNI 969
            I + S  I
Sbjct: 214 EIVKSSDGI 222

to top

>Q46078:KPYK_CORGL Pyruvate kinase - Corynebacterium glutamicum (Brevibacterium flavum)|
          Length = 475

 Score =  106 bits (265), Expect = 4e-22
 Identities = 65/177 (36%), Positives = 101/177 (57%), Gaps = 1/177 (0%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            + +   + I+   D ++++RG+LG+++P E+V L QK A+       KP +V T+++DSM
Sbjct: 223  EAVTSLEPIVLAFDAVMVARGDLGVEVPLEEVPLVQKRAIQIARENAKPVIVATQMLDSM 282

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLY 1435
             +N RPTRAEA+DVANAVLDG+DA++L  ET  G  P   + T+ RI   AE        
Sbjct: 283  IENSRPTRAEASDVANAVLDGADAVMLSGETSVGKDPHNVVRTMSRIVRFAET------- 335

Query: 1436 FKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVL 1606
              R       P T    I+ SA   A ++ A  ++ FT+SG  A+ +A+    +P+L
Sbjct: 336  DGRVPDLTHIPRTKRGVISYSARDIAERLNARALVAFTTSGDTAKRVARLHSHLPLL 392



 Score = 81.6 bits (200), Expect = 2e-14
 Identities = 60/236 (25%), Positives = 115/236 (48%), Gaps = 1/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP   S + I   ++ GM VAR +FS GD   H++  + ++ A + T +   +
Sbjct: 5   TKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAVGI 64

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           + D  GP++++   ++     E  E++ +T     E +   +   +  LAK  KPG  + 
Sbjct: 65  LADLQGPKIRLGRFTDGATVWENGETIRITV-DDVEGTHDRVSTTYKNLAKDAKPGDRLL 123

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED- 783
           V        +   V L    V+G+DV+C +     ++ +   +    + I +P LS++D 
Sbjct: 124 V--------DDGKVGLVCVSVEGNDVICEVVEGGPVSNNK-GVSLPGMDISVPALSEKDI 174

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVIS 951
           +D+  ++     +DF++LS+ R   D     + + + G   +  + AK+E  E ++
Sbjct: 175 RDL--RFALKLGVDFIALSFVRSPADAELVHKIMDEEG--RRVPVIAKLEKPEAVT 226

to top

>Q89AI8:KPYK_BUCBP Pyruvate kinase - Buchnera aphidicola subsp. Baizongia pistaciae|
          Length = 479

 Score =  106 bits (265), Expect = 4e-22
 Identities = 69/203 (33%), Positives = 117/203 (57%), Gaps = 5/203 (2%)
 Frame = +2

Query: 1073 SLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVD 1249
            +++ L   DEI+  +D I+++RG+LG+++   ++   QK+ + +     +  +  T++++
Sbjct: 229  AVKDLKIIDEIILASDAIMVARGDLGVEIGESELAGIQKTLIRRARQLNRVVITATQMME 288

Query: 1250 SMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQD 1429
            SM +N  PTRAE  DVANAVLDGSDA++L AET  G YP+ETI  + ++C  AEK+ + +
Sbjct: 289  SMINNPMPTRAEVMDVANAVLDGSDAVMLSAETASGKYPIETIKVMSKVCMGAEKMPSIN 348

Query: 1430 LYFKRTVKYVGEPMTHL-ESIASSAVRAAIKVKA-SVIICFTSSGRAARLIAKYRPTMPV 1603
            +   R    + +    + E+IA SA+ AA  +   + II  T SG+ + + ++    +P+
Sbjct: 349  VSQHR----IHDKFHDIEEAIAMSAMYAANHLSGITAIITMTESGKTSLMTSRITSGLPI 404

Query: 1604 --LSVVIPRLKTNQLKWSFTGAF 1666
              LS  I  LK   L    T  F
Sbjct: 405  FALSSHIQTLKLTALYRGVTPIF 427



 Score = 56.2 bits (134), Expect = 7e-07
 Identities = 56/239 (23%), Positives = 112/239 (46%), Gaps = 5/239 (2%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKL--- 417
           TKIV TLGP + +   +   +K+G++V R +FS G     +E +   K+     K+L   
Sbjct: 8   TKIVATLGPSTDNHIILENMIKSGVNVFRLNFSHGT---REEHIYRAKLVTSIAKRLNCH 64

Query: 418 CAVMLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQE-ASSKLLPINFSGLAKAVKPG 594
            A++ D  GP++++    +  + L+ N   +L  +  +   +S+ + I++  L K VK  
Sbjct: 65  IALLGDLQGPKIRICKFQDKKVFLKVNNYFILDANLNENLGTSERVGIDYKNLPKDVKKC 124

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             + +        +   + L+V  +   ++   I     L+ +   ++     +    L+
Sbjct: 125 DILLL--------DDGKIQLKVINIVDQEIFTKIIIGGVLSNNK-GINKLGGGLSARILT 175

Query: 775 DEDK-DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
            +DK D++        +D+L++S+ R+  D+  AR+   K G  S+  I AKIE  E +
Sbjct: 176 KKDKRDIIT--SIDIGVDYLAVSFPRYGSDLDHARKCAVKFG--SKAKIIAKIERAEAV 230

to top

>Q8FP04:KPYK_COREF Pyruvate kinase - Corynebacterium efficiens|
          Length = 474

 Score =  106 bits (264), Expect = 6e-22
 Identities = 66/171 (38%), Positives = 99/171 (57%), Gaps = 1/171 (0%)
 Frame = +2

Query: 1097 DEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMTDNLRP 1273
            + I+   D I+++RG+LG+++P E+V L QK A+       KP +V T+++DSM +N RP
Sbjct: 229  ESIVLAFDAIMVARGDLGVEVPLEEVPLVQKRAIQIARENAKPVIVATQMLDSMIENSRP 288

Query: 1274 TRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKRTVK 1453
            TRAEA+DVANAVLDG+DA++L  ET  G  P   + T+ RI   AE          R   
Sbjct: 289  TRAEASDVANAVLDGADAVMLSGETSVGKDPHNVVRTMSRIVRFAET-------DGRVPD 341

Query: 1454 YVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVL 1606
                P T    I+ SA   A ++ A  ++ FT+SG  A+ +A+    +P+L
Sbjct: 342  LTHIPRTKRGVISYSARDIAERLNARALVAFTTSGDTAKRLARLHSHLPLL 392



 Score = 83.2 bits (204), Expect = 5e-15
 Identities = 63/236 (26%), Positives = 114/236 (48%), Gaps = 1/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP   S + I   ++ GM VAR +FS GD   H++  + ++ A   T +   +
Sbjct: 5   TKIVCTLGPAVASADGILRLVQDGMDVARLNFSHGDHPDHEQNYKWVREATDKTGRAVGI 64

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           + D  GP++++    E +   E  E+V +T     E +   +   +  LAK  +PG  + 
Sbjct: 65  LADLQGPKIRLGRFKEGSTVWETGETVRITV-DDVEGTHDRVSTTYKNLAKDARPGDRLL 123

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED- 783
           V        +   V L    V+G+DV+C +     ++ +   +    + I +P LS++D 
Sbjct: 124 V--------DDGKVGLVCVSVEGNDVICEVTEGGPVSNNK-GVSLPGMDISVPALSEKDI 174

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVIS 951
           KD+  ++     +DF++LS+ R   DV      + + G   +  + AK+E  E ++
Sbjct: 175 KDL--RFALKLGVDFIALSFVRSPADVELVHAIMDEEG--RRVPVIAKLEKPEAVA 226

to top

>Q8ZNW0:KPYK2_SALTY Pyruvate kinase II - Salmonella typhimurium|
          Length = 480

 Score =  105 bits (263), Expect = 8e-22
 Identities = 62/178 (34%), Positives = 108/178 (60%), Gaps = 3/178 (1%)
 Frame = +2

Query: 1088 NHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMTDN 1264
            N  D+I+  +D ++++RG+LG+++   ++   QK+ + +     +  +  T++++SM  N
Sbjct: 234  NAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITN 293

Query: 1265 LRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKR 1444
              PTRAE  DVANAVLDG+DA++L AET  G YP ET++ + R+C  AEK+ + ++   R
Sbjct: 294  PMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMARVCLGAEKIPSINVSKHR 353

Query: 1445 -TVKYVGEPMTHLESIASSAVRAAIKVK-ASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
              V++        E+IA SA+ AA  +K  + II  T SGR A + ++    +P+ ++
Sbjct: 354  LDVQFDNVE----EAIAMSAMYAANHLKGVTAIITMTESGRTALMTSRISSGLPIFAM 407



 Score = 64.7 bits (156), Expect = 2e-09
 Identities = 59/235 (25%), Positives = 106/235 (45%), Gaps = 1/235 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP +     +   + AG +V R +FS G    H+   + ++       +  A+
Sbjct: 8   TKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAKLGRHVAI 67

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQ-EASSKLLPINFSGLAKAVKPGATI 603
           + D  GP+++V    E  + L   +  +L  + G+ E   + + I++ GL   V PG  +
Sbjct: 68  LGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGKGEGDKEKVGIDYKGLPADVVPGDIL 127

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
            +        +   V L+V EVQG  V   +     L+ +   ++     +    L+++D
Sbjct: 128 LL--------DDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK-GINKLGGGLSAEALTEKD 178

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           K  ++   A   +D+L++S+ R  ED+  AR      G      I AK+E  E +
Sbjct: 179 KADIQT-AALIGVDYLAVSFPRCGEDLNYARRLARDAG--CDAKIVAKVERAEAV 230

to top

>O51323:KPYK_BORBU Pyruvate kinase - Borrelia burgdorferi (Lyme disease spirochete)|
          Length = 477

 Score =  105 bits (261), Expect = 1e-21
 Identities = 56/181 (30%), Positives = 105/181 (58%), Gaps = 6/181 (3%)
 Frame = +2

Query: 1079 QGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSM 1255
            +G+++ +EI + + GI+++RG++G+++P E V + Q      C   G P +  T+++ +M
Sbjct: 219  EGIDNIEEIAKASYGIMVARGDMGVEIPAEDVPIAQLKITQTCIKYGIPVITATQMLHTM 278

Query: 1256 TDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEK-----VF 1420
             +N RPTRAE +D+ANA+L+G+DAI+L  ET  G YP+E +  +  I  + EK     ++
Sbjct: 279  IENPRPTRAEVSDIANAILNGTDAIMLSGETAYGKYPIEAVKMMTSIAKKVEKHRKMTLY 338

Query: 1421 NQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMP 1600
              +L++ +++            I   A+ A   +    II  +  G+ AR++A YR ++P
Sbjct: 339  KDELFYDKSIT--------RNYIIKCAIDATKLMDIKAIIVDSLKGKTARIMATYRASVP 390

Query: 1601 V 1603
            +
Sbjct: 391  L 391



 Score = 72.0 bits (175), Expect = 1e-11
 Identities = 61/248 (24%), Positives = 123/248 (49%), Gaps = 6/248 (2%)
 Frame = +1

Query: 244 MTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCA 423
           +TKIV T+       E I     AG++V R + +      H++T++ +    K + K+ A
Sbjct: 5   LTKIVATISDLRCEPEHIKDLHDAGVNVIRLNTAHQS---HEDTIKVIDNVRKISNKI-A 60

Query: 424 VMLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATI 603
           +M+DT GPE++  N  E  I ++  + V+++     E ++     N+ G  K V  G+ +
Sbjct: 61  LMIDTKGPEVRTAN-IENPIIVKTGDKVIISTSPINEPNN--FQTNYDGFVKEVPQGSKV 117

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
            +        +   + + V     D ++C IKN   +     +++   I + + +++++D
Sbjct: 118 LI--------DDGELEMTVVAKLPDRLICEIKNDGQIKNKK-SINTPGISLKLQSVTEKD 168

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIE------NVEV 945
           K  ++   A   +DF++ S+ RH++DV+  +E L+  G+     I +KIE      N+E 
Sbjct: 169 KGFIEL-AAKYNVDFIAHSFVRHSKDVQDVQEILTASGN-PDVKIISKIENQEGIDNIEE 226

Query: 946 ISRYSFNI 969
           I++ S+ I
Sbjct: 227 IAKASYGI 234

to top

>P21599:KPYK2_ECOLI Pyruvate kinase II - Escherichia coli|
          Length = 480

 Score =  104 bits (259), Expect = 2e-21
 Identities = 61/175 (34%), Positives = 107/175 (61%), Gaps = 3/175 (1%)
 Frame = +2

Query: 1097 DEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMTDNLRP 1273
            D+I+  +D ++++RG+LG+++   ++   QK+ + +     +  +  T++++SM  N  P
Sbjct: 237  DDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMP 296

Query: 1274 TRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKR-TV 1450
            TRAE  DVANAVLDG+DA++L AET  G YP ET++ + R+C  AEK+ + ++   R  V
Sbjct: 297  TRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMARVCLGAEKIPSINVSKHRLDV 356

Query: 1451 KYVGEPMTHLESIASSAVRAAIKVK-ASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
            ++        E+IA SA+ AA  +K  + II  T SGR A + ++    +P+ ++
Sbjct: 357  QFDNVE----EAIAMSAMYAANHLKGVTAIITMTESGRTALMTSRISSGLPIFAM 407



 Score = 66.2 bits (160), Expect = 7e-10
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 1/235 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP +     +   + AG +V R +FS G    H+   + ++       +  A+
Sbjct: 8   TKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAKLGRHVAI 67

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQ-EASSKLLPINFSGLAKAVKPGATI 603
           + D  GP+++V    E  + L   +  +L  + G+ E   + + I++ GL   V PG  +
Sbjct: 68  LGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGKGEGDKEKVGIDYKGLPADVVPGDIL 127

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
            +        +   V L+V EVQG  V   +     L+ +   ++     +    L+++D
Sbjct: 128 LL--------DDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK-GINKLGGGLSAEALTEKD 178

Query: 784 KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           K  +K   A   +D+L++S+ R  ED+  AR      G      I AK+E  E +
Sbjct: 179 KADIKT-AALIGVDYLAVSFPRCGEDLNYARRLARDAG--CDAKIVAKVERAEAV 230

to top

>P43924:KPYK_HAEIN Pyruvate kinase - Haemophilus influenzae|
          Length = 478

 Score =  103 bits (258), Expect = 3e-21
 Identities = 61/174 (35%), Positives = 106/174 (60%), Gaps = 2/174 (1%)
 Frame = +2

Query: 1097 DEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMTDNLRP 1273
            D+I+  +D I+++RG+LG+++   ++   QK  + +     +  +  T++++SM  N  P
Sbjct: 237  DDIILASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMP 296

Query: 1274 TRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKRTVK 1453
            TRAE  DVANAVLDG+DA++L AET  G YP ET++ +  +C  AEK+ + ++   R  K
Sbjct: 297  TRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMASVCLGAEKMPSINVSRHRMDK 356

Query: 1454 YVGEPMTHLESIASSAVRAAIKVK-ASVIICFTSSGRAARLIAKYRPTMPVLSV 1612
               E  T  ES+A SA+ AA  +K  + I+  +S+GR   L+++    +P+ ++
Sbjct: 357  ---EFETIEESVAMSAMYAANHMKGVAAIVTLSSTGRTPLLMSRISSGLPIFAL 407



 Score = 60.5 bits (145), Expect = 4e-08
 Identities = 59/238 (24%), Positives = 107/238 (44%), Gaps = 3/238 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV T+GP +     +   + AG +V R +FS G    H    E ++   K   K  A+
Sbjct: 8   TKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAI 67

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPH--KGQEASSKLLPINFSGLAKAVKPGAT 600
           + D  GP+++V    +  I L   +  +L     KG E + + + +++  L + V PG  
Sbjct: 68  LGDLQGPKIRVSTFKDGKIFLNVGDKFILDAELPKG-EGTQESVGLDYKTLPQDVVPGDI 126

Query: 601 IFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           + +        +   V L+V    G  V   +     L+ +   ++     +    L+++
Sbjct: 127 LLL--------DDGRVQLKVLSTDGAKVFTEVTVGGPLSNNK-GINKLGGGLSADALTEK 177

Query: 781 DK-DVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVIS 951
           DK D++    A   +DFL++S+ R + D+  ARE   + G      I AK+E  E ++
Sbjct: 178 DKADIIT--AARIGVDFLAVSFPRSSADLNYARELAQQAG--LNAKIVAKVERAETVA 231

to top

>Q8K9M3:KPYK_BUCAP Pyruvate kinase - Buchnera aphidicola subsp. Schizaphis graminum|
          Length = 481

 Score =  102 bits (255), Expect = 6e-21
 Identities = 63/177 (35%), Positives = 105/177 (59%), Gaps = 2/177 (1%)
 Frame = +2

Query: 1088 NHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMTDN 1264
            N  + I+  +D I+++RG+LG+++   ++   QK  +       K A+  T++++SM  N
Sbjct: 234  NAIENIILSSDAIMIARGDLGVEIGDAELVGIQKKLIRTARKLNKVAITATQMMESMILN 293

Query: 1265 LRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKR 1444
              PTRAE  DVANAVLDGSDA++L AET  G YP ET+ ++ ++C  AEKV + ++   R
Sbjct: 294  PLPTRAEVMDVANAVLDGSDAVMLSAETASGKYPSETVISMAKVCKGAEKVPSINVSRHR 353

Query: 1445 TVKYVGEPMTHLESIASSAVRAAIKVKA-SVIICFTSSGRAARLIAKYRPTMPVLSV 1612
                  E  +  E+IA S++ AA  +K  + II  T SG+ A + ++    +P+ ++
Sbjct: 354  LNV---EFQSIEEAIAMSSMYAANHLKGITAIITMTESGKTALMTSRITSGLPIFAL 407



 Score = 60.5 bits (145), Expect = 4e-08
 Identities = 55/239 (23%), Positives = 115/239 (48%), Gaps = 5/239 (2%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP +     +   + +G +V R +FS G +  H++  +  K  +       A+
Sbjct: 8   TKIVATLGPSTDKANNLEKIILSGANVLRLNFSHGSSEEHKKRAKKAKEIMFKLNCHIAL 67

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQE-ASSKLLPINFSGLAKAVKPGATI 603
           + D  GP++++    + +I L+ N+  +L  +  ++  +++ + I++  L   +     +
Sbjct: 68  LGDLQGPKIRISKFKKNSIFLKVNDVFILDANLNEKNGNNERVGIDYKKLPNDLNVNDIL 127

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFT---LHCSQIHIDMPTLS 774
            +        +   + L+V +++     C I     + G L     ++     +    L+
Sbjct: 128 LL--------DDGRIQLKVIKIE----KCAIFTKVIIGGILSNNKGINKLGGGLSADALT 175

Query: 775 DED-KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           ++D KD++    +   +D+L++S+ R A+D+ +ARE L K G  +Q  I AKIE  E +
Sbjct: 176 EKDKKDII--LASEIDVDYLAVSFPRCADDLIKARELLKKSGSNAQ--IIAKIERAEAV 230

to top

>P57404:KPYK_BUCAI Pyruvate kinase - Buchnera aphidicola subsp. Acyrthosiphon pisum|
            (Acyrthosiphon pisum symbiotic bacterium)
          Length = 480

 Score =  100 bits (249), Expect = 3e-20
 Identities = 61/177 (34%), Positives = 102/177 (57%), Gaps = 2/177 (1%)
 Frame = +2

Query: 1088 NHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMTDN 1264
            N  ++I+  +D I+++RG+LG+++   ++   QK  +       +  +  T++++SM  N
Sbjct: 234  NTIEDIILASDAIMIARGDLGVEIGDSELAGIQKKLIRTARQLNRIVITATQMMESMITN 293

Query: 1265 LRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKR 1444
              PTRAE  DVANAVLDGSDA++L AET  G YP ET+  + +IC  AEKV + ++   R
Sbjct: 294  PLPTRAEVMDVANAVLDGSDAVMLSAETASGEYPAETVIKMAKICKGAEKVPSINVSRHR 353

Query: 1445 TVKYVGEPMTHLESIASSAVRAAIKVKA-SVIICFTSSGRAARLIAKYRPTMPVLSV 1612
                  +     E+IA SA+  A  +K  + II  T SG+ A + ++    +P+ ++
Sbjct: 354  IHAKFDDIE---EAIAMSAMYVANHLKGITAIITMTESGKTALMTSRITSGLPIFAL 407



 Score = 58.5 bits (140), Expect = 1e-07
 Identities = 52/236 (22%), Positives = 110/236 (46%), Gaps = 2/236 (0%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKIV TLGP +     +   +++G++V RF+FS G    H+      +  +       A+
Sbjct: 8   TKIVATLGPSTDINNNLEKIIRSGVNVLRFNFSHGSKDEHKSRANQAREIMTRLNFHIAL 67

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQ-EASSKLLPINFSGLAKAVKPGATI 603
           + D  GP++++    +  I L   +  +L  +  Q   + + + I++  L   +K G  +
Sbjct: 68  LGDLQGPKIRISKFIKNNIFLNVGDFFILDANLDQNNGNQERVGIDYKQLPYDLKVGDVL 127

Query: 604 FVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDED 783
            +        +   + L+V +  G +++  +     L+ +   ++     +    L+++D
Sbjct: 128 LL--------DDGRIQLKVIKSTGHEILTKVVIGGILSNNK-GINKLGGGLSADALTEKD 178

Query: 784 -KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
            KD++        +D+L++S+ R + D++QAR+   + G  S   I AKIE  E +
Sbjct: 179 KKDII--LATEINVDYLAISFPRCSNDLKQARKLAKEFG--SNAKIIAKIERAEAV 230

to top

>Q56301:KPYK_THELI Pyruvate kinase - Thermococcus litoralis|
          Length = 220

 Score = 94.4 bits (233), Expect = 2e-18
 Identities = 64/218 (29%), Positives = 115/218 (52%), Gaps = 3/218 (1%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKI+ T+GP S+  E+I   +KAGMSVAR +FS G    H +T+E ++   +  ++  A+
Sbjct: 12  TKIIATIGPASKQKESIKKMIKAGMSVARINFSHGTLEEHAKTIETVRDVAEKLERRVAI 71

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIF 606
           + D  G +++V      +++L + + VVLT  +  E     +P+ F  L K V  G TI 
Sbjct: 72  LGDLPGLKMRVGKIKGDSVTLRKGDKVVLTT-RDIEGDETTIPVEFKDLPKLVSKGDTI- 129

Query: 607 VGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFT---LHCSQIHIDMPTLSD 777
              YL  G     + L V EV+ ++V CV+ N     G LF+   ++  + ++ +  ++ 
Sbjct: 130 ---YLSDG----YIMLRVEEVRENEVECVVVN----GGILFSHKGINIPKANLPIEAITP 178

Query: 778 EDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSK 891
            D +++ ++   + +D + LS+     DV + + FL K
Sbjct: 179 RDFEII-EFAIEHGVDAIGLSFVGSVYDVLKVKSFLEK 215

to top

>Q43117:KPYA_RICCO Pyruvate kinase isozyme A, chloroplast precursor - Ricinus communis|
            (Castor bean)
          Length = 583

 Score = 94.0 bits (232), Expect = 3e-18
 Identities = 51/183 (27%), Positives = 100/183 (54%), Gaps = 4/183 (2%)
 Frame = +2

Query: 1073 SLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVD 1249
            S+  L + +EI+  +DG +++RG+LG  +P E+V   Q++ +  C    KP +V +++++
Sbjct: 334  SIDSLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSAQQNIVQVCRQLNKPVIVASQLLE 393

Query: 1250 SMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQD 1429
            SM +   PTRAE  DV+ AV   +DA++L  E+  G YP + ++ +  +    EK + ++
Sbjct: 394  SMIEYPTPTRAEVADVSEAVRQRADALMLSGESAMGQYPEKALAVLRSVSVRIEKWWREE 453

Query: 1430 LYFK-RTVKYVGEPMTH--LESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMP 1600
             + +   +  +G   +    E I +SA + A  +    +  +T  G  A L+++ RP  P
Sbjct: 454  KHHEAMELPAIGSTYSDSISEEICNSAAKMANNLGVDALFVYTKDGHMASLLSRCRPDCP 513

Query: 1601 VLS 1609
            + +
Sbjct: 514  IFA 516



 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 58/241 (24%), Positives = 112/241 (46%), Gaps = 9/241 (3%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TK+V T+GP +   E + A    GM+VAR +   G   +H+  +E ++   +      A+
Sbjct: 106 TKLVCTIGPATCGFEELEALAVGGMNVARINMCHGTREWHKSVIERVRRLNEEKGFAVAI 165

Query: 427 MLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEA--SSKLLPINFSGLAKAVKPGAT 600
           M+DT G E+ + +    + +  E+  +     +  ++    + + +N+ G A+ VK G  
Sbjct: 166 MMDTEGSEIHMGDLGGASSAKAEDGEIWTFSVRAYDSPRPERTINVNYDGFAEDVKVGDE 225

Query: 601 IFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATL---AGSLFTLHCSQI---HIDM 762
           + V        +   V  EV E  G DV C   +   L   A   F    S +   +  +
Sbjct: 226 LLV--------DGGMVRFEVIEKIGPDVKCRCTDPGLLLPRANLTFWRDGSLVRERNAML 277

Query: 763 PTLSDED-KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENV 939
           PT+S +D  D+   +G    +DF+++S+ + AE +   + +++     S   + AKIE++
Sbjct: 278 PTISSKDWLDI--DFGIAEGVDFIAISFVKSAEVINHLKSYIAARSRDSDIAVIAKIESI 335

Query: 940 E 942
           +
Sbjct: 336 D 336

to top

>Q40546:KPYG_TOBAC Pyruvate kinase isozyme G, chloroplast precursor - Nicotiana tabacum|
            (Common tobacco)
          Length = 562

 Score = 92.8 bits (229), Expect = 7e-18
 Identities = 53/188 (28%), Positives = 99/188 (52%), Gaps = 1/188 (0%)
 Frame = +2

Query: 1049 VHHLFTPYSLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPA 1228
            +H +    S   + +   I+  +DG +++RG+LG +LP E+V L Q+  + +C    KP 
Sbjct: 301  IHVIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCQSMQKPV 360

Query: 1229 VV-TRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAE 1405
            +V T +++SM D+  PTRAE +D++ AV +G+DA++L  ET  G YP++ +  +  +   
Sbjct: 361  IVATNMLESMIDHPTPTRAEVSDISIAVREGADAVMLSGETAHGKYPLKAVKVMHIVALR 420

Query: 1406 AEKVFNQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKY 1585
             E    +              M  + +  SS++   +   ++ II FT +G  A +++  
Sbjct: 421  TESSLQKSTSSPSQSAAYKSHMGEMFAFHSSSMANTL---STPIIVFTRTGSMAIILSHN 477

Query: 1586 RPTMPVLS 1609
            RP+  V +
Sbjct: 478  RPSSTVFA 485



 Score = 81.3 bits (199), Expect = 2e-14
 Identities = 66/238 (27%), Positives = 118/238 (49%), Gaps = 1/238 (0%)
 Frame = +1

Query: 238 PAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLK-IAIKATKK 414
           P  TKIV T+GP + S E I    +AGM+VAR + S GD A HQ T++ +K    +   K
Sbjct: 90  PRKTKIVCTIGPSTSSREMIWKLAEAGMNVARLNMSHGDHASHQRTIDLVKEYNAQFEDK 149

Query: 415 LCAVMLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPG 594
           + A+MLDT GPE+ +       I L+E +    +  +G  ++   + +N+      V+ G
Sbjct: 150 VIAIMLDTKGPEV-ISGDVPKPILLKEGQEFNFSIKRG-VSTEDTVSVNYDDFINDVEAG 207

Query: 595 ATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLS 774
             + V   + +        L V     D V C + +   L  S   L+       +P+++
Sbjct: 208 DILLVDGGMMS--------LAVKSKTSDIVKCEVIDGGELK-SRRHLNVRGKSATLPSIT 258

Query: 775 DEDKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           ++D D + K+G  N++DF ++S+ + A+ V + +++L      +   +  KIE+ + I
Sbjct: 259 EKDWDDI-KFGVNNQVDFYAVSFVKDAKVVHELKDYLKSCN--ADIHVIVKIESADSI 313

to top

>P55964:KPYG_RICCO Pyruvate kinase isozyme G, chloroplast - Ricinus communis (Castor|
            bean)
          Length = 418

 Score = 92.4 bits (228), Expect = 9e-18
 Identities = 57/204 (27%), Positives = 100/204 (49%), Gaps = 19/204 (9%)
 Frame = +2

Query: 1049 VHHLFTPYSLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPA 1228
            +H +    S   + +   I+  +DG +++RG+LG +LP E+V L Q+  + +C+   KP 
Sbjct: 158  IHVIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPV 217

Query: 1229 VV-TRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAE 1405
            +V T +++SM ++  PTRAE +D+A AV +G+DA++L  ET  G YP++ +  +  +   
Sbjct: 218  IVATNMLESMINHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKYPLKAVRVMHTVALR 277

Query: 1406 AEKV----------------FNQDLYFKRTV--KYVGEPMTHLESIASSAVRAAIKVKAS 1531
             E                    +   F  T+    +  P+       S AV  +    AS
Sbjct: 278  TESSSPVNTTPPAQGAYKGHMGEMFAFHATIMANTLNTPIIVFTRTGSMAVLLSHYQPAS 337

Query: 1532 VIICFTSSGRAARLIAKYRPTMPV 1603
             I  FT+  R  + ++ YR  MP+
Sbjct: 338  TIFAFTNEERIKQRLSLYRGVMPI 361



 Score = 43.1 bits (100), Expect = 0.006
 Identities = 41/176 (23%), Positives = 83/176 (47%)
 Frame = +1

Query: 421 AVMLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGAT 600
           ++MLDT GPE++  +  +    L+E +    T  +G  ++   + +N+      V  G  
Sbjct: 10  SIMLDTKGPEVRSGDVPQPM--LKEGQEFNPTIRRGV-STQDTVSVNYDDFVNDVVVGDI 66

Query: 601 IFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDE 780
           + V   + +        L V     D V CV+ +   L  S   L+       +P+++D+
Sbjct: 67  LLVDGGMMS--------LAVKSKTSDLVKCVVVDGGELK-SRRHLNVRGKSARLPSITDK 117

Query: 781 DKDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVI 948
           D   +K +G  N++DF ++S+ + A+ V + +E+L +    +   +  KIE+ + I
Sbjct: 118 DWGDIK-FGVDNQVDFYAVSFVKDAKVVHELKEYLKRCN--ADIHVIVKIESADSI 170

to top

>P47458:KPYK_MYCGE Pyruvate kinase - Mycoplasma genitalium|
          Length = 508

 Score = 89.7 bits (221), Expect = 6e-17
 Identities = 47/130 (36%), Positives = 82/130 (63%), Gaps = 5/130 (3%)
 Frame = +2

Query: 1073 SLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVD 1249
            S   LN+ D+I++ +DGI+++RG+LG+++P  +V  +Q+  +  C    K ++  T+++D
Sbjct: 252  SNHALNNIDKIIKASDGIMVARGDLGLEIPYYQVPYWQRYMIKACRFFNKRSITATQMLD 311

Query: 1250 SMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVF--- 1420
            S+  N++PTRAE TDV  AV  G+DA +L  ET  GLYP+  ++ + +I  ++E  F   
Sbjct: 312  SLEKNIQPTRAEVTDVYFAVDRGNDATMLSGETASGLYPLNAVAVMQKIDKQSETFFDYQ 371

Query: 1421 -NQDLYFKRT 1447
             N + Y K +
Sbjct: 372  YNVNYYLKNS 381



 Score = 78.2 bits (191), Expect = 2e-13
 Identities = 68/255 (26%), Positives = 118/255 (46%), Gaps = 25/255 (9%)
 Frame = +1

Query: 247 TKIVGTLGP--------------------KSRSVEAISACLKAGMSVARFDFSWGDAAYH 366
           TKI+ T GP                    K  +   I A +K+G+SV R +FS G     
Sbjct: 8   TKIIATCGPALTKSLVSLKMLDDNEYAAIKKVAYANIEAIIKSGVSVIRLNFSHGTHEEQ 67

Query: 367 QETLENLKIAIKATKKLCAVMLDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSK 546
           Q  ++ ++   KA     ++MLDT GPE+++V   +  + + ++  V++       AS  
Sbjct: 68  QVRIKIVRDVAKAMNIPVSIMLDTNGPEIRIVETKKEGLKITKDSEVIINTMSKMIASDN 127

Query: 547 LLPI-NFSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGS 723
              + + SG    V     + +GQ +       ++ +   + Q + V+CV KN  T    
Sbjct: 128 QFAVSDASGKYNMVN---DVNIGQKILVDDGKLTLVVTRVDKQHNQVICVAKNDHT---- 180

Query: 724 LFT---LHCSQIHIDMPTLSDED-KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSK 891
           +FT   L+       +P LS++D KD+   +G    ID+++ S+     D++Q R++L K
Sbjct: 181 VFTKKRLNLPNAQYSIPFLSEKDLKDI--DFGLSQGIDYIAASFVNTVADIKQLRDYL-K 237

Query: 892 LGDLSQTLIFAKIEN 936
           L + S   I AKIE+
Sbjct: 238 LKNASGVKIIAKIES 252

to top

>Q40545:KPYA_TOBAC Pyruvate kinase isozyme A, chloroplast precursor - Nicotiana tabacum|
            (Common tobacco)
          Length = 593

 Score = 87.4 bits (215), Expect = 3e-16
 Identities = 47/185 (25%), Positives = 99/185 (53%), Gaps = 6/185 (3%)
 Frame = +2

Query: 1073 SLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVD 1249
            S+  L + +EI++ +DG +++RG+LG  +P E+V   Q+  +  C    +P +V +++++
Sbjct: 344  SIDSLKNLEEIIQASDGAMVARGDLGAQIPLEQVPSEQQKIVQICRQLNRPVIVASQLLE 403

Query: 1250 SMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQD 1429
            SM +   PTRAE  DV+ AV    DA++L  E+  G +P + ++ +  +    E+++ + 
Sbjct: 404  SMIEYPIPTRAEVADVSEAVRQRGDALMLSGESAMGQFPEKALTVLRSVSLRIERMWREQ 463

Query: 1430 -----LYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPT 1594
                 +          + ++  E I +SA + A  ++   +  +T +G  A L+++ RP 
Sbjct: 464  KRHEVIELPSIASSFSDSIS--EEICNSAAKMANNLEVDALFVYTKNGHMASLLSRCRPD 521

Query: 1595 MPVLS 1609
             P+ +
Sbjct: 522  CPIFA 526



 Score = 67.8 bits (164), Expect = 2e-10
 Identities = 56/241 (23%), Positives = 109/241 (45%), Gaps = 9/241 (3%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TK++ T+GP +   E +    + GM+VAR +   G   +H+  +E L+   +      A+
Sbjct: 116 TKLICTIGPATCGFEQLERLAEGGMNVARINMCHGTREWHRMVIERLRRLNEEKGFAVAI 175

Query: 427 MLDTVGPELQVVNKSEVTISLEENESV--VLTPHKGQEASSKLLPINFSGLAKAVKPGAT 600
           M+DT G E+ + +    + +  E+  +              + + +N+ G A+ VK G  
Sbjct: 176 MMDTEGSEIHMGDLGGASSAKAEDGEIWNFTVRSFDPPLPERTVTVNYDGFAEDVKVGDE 235

Query: 601 IFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATL---AGSLFTLHCSQI---HIDM 762
           + V        +   V  EV E  G DV C+  +   L   A   F      +   +  +
Sbjct: 236 LLV--------DGGMVRFEVIEKIGPDVKCLCTDPGLLLPRANLTFWRDGKLVRERNAML 287

Query: 763 PTLSDED-KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENV 939
           PT+S +D  D+   +G    +DF+++S+ + AE ++  + ++      S   + AKIE++
Sbjct: 288 PTISSKDWLDI--DFGIAEGVDFIAVSFVKSAEVIKHLKSYIQARARDSDISVIAKIESI 345

Query: 940 E 942
           +
Sbjct: 346 D 346

to top

>P78031:KPYK_MYCPN Pyruvate kinase - Mycoplasma pneumoniae|
          Length = 508

 Score = 84.0 bits (206), Expect = 3e-15
 Identities = 43/118 (36%), Positives = 73/118 (61%), Gaps = 1/118 (0%)
 Frame = +2

Query: 1073 SLQGLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVD 1249
            S   LN+ D I++ +DGI+++RG+LG+++P  KV  +Q+  +  C    K  +  T+++D
Sbjct: 252  SNHALNNIDGIIKASDGIMVARGDLGLEIPYYKVPYWQRYMIKACRFFNKRVITATQMLD 311

Query: 1250 SMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFN 1423
            S+  N++PTRAE TDV  AV  G+DA +L  ET  G +P+  +  +  I  ++E  F+
Sbjct: 312  SLEKNIQPTRAEVTDVYFAVDRGNDATMLSGETANGAFPLNAVYVMKMIDKQSETFFD 369



 Score = 73.6 bits (179), Expect = 4e-12
 Identities = 67/250 (26%), Positives = 124/250 (49%), Gaps = 17/250 (6%)
 Frame = +1

Query: 238 PAMTKIVGTLGP---------KSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLK 390
           PA+TK + TL           K+ +   I   +K G++V R +FS G+   H+E    +K
Sbjct: 16  PALTKKLWTLAMLDDPAYAAMKAEAYANIENIIKNGVTVIRLNFSHGN---HEEQAVRIK 72

Query: 391 IAIKATKKL---CAVMLDTVGPELQVVNKSEVTIS-LEENESVVLTPHKGQEASSKLLPI 558
           I     KKL    ++MLDT GPE++V   +   +  L+++E V+ T  K    +++    
Sbjct: 73  IVRDVAKKLNLPVSIMLDTNGPEIRVFETAPEGLKILKDSEVVINTTTKEVAKNNQFSVS 132

Query: 559 NFSGLAKAVKPGATIFVGQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFT-- 732
           + SG    V     + VGQ +       S+ ++  + + + V+CV +N  T    +FT  
Sbjct: 133 DASGTYNMVN---DVKVGQKILVDDGKLSLVVKRIDTKNNQVICVAQNDHT----IFTKK 185

Query: 733 -LHCSQIHIDMPTLSDED-KDVMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLS 906
            L+       +P LS +D +D+   +G  ++ID+++ S+    E+++Q R++L+   +  
Sbjct: 186 RLNLPNADYSIPFLSAKDLRDI--DFGLTHQIDYIAASFVNTTENIKQLRDYLAS-KNAK 242

Query: 907 QTLIFAKIEN 936
              + AKIE+
Sbjct: 243 HVKLIAKIES 252

to top

>Q8ZYE0:KPYK_PYRAE Pyruvate kinase - Pyrobaculum aerophilum|
          Length = 461

 Score = 79.7 bits (195), Expect = 6e-14
 Identities = 56/190 (29%), Positives = 97/190 (51%), Gaps = 2/190 (1%)
 Frame = +2

Query: 1028 ILEQL*FVHHLFTPYSLQG-LNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHK 1204
            +L +L F   +      +G +N+ +E+++ +D ++++RG+LG+    + + + Q+  +H 
Sbjct: 217  LLTELGFQSQVAVKIETKGAVNNLEELVQCSDYVVVARGDLGLHYGLDALPIVQRRIVHT 276

Query: 1205 CNMAGKP-AVVTRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETIS 1381
                GKP AV T+++DSM  +  PTRAE  DV      G D++ L  ET  G YP+  +S
Sbjct: 277  SLKYGKPIAVATQLLDSMQSSPIPTRAEINDVFTTASMGVDSLWLTNETASGKYPLAAVS 336

Query: 1382 TVGRICAEAEKVFNQDLYFKRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGR 1561
             + RI    E    Q    + +           +  A   V  A  + A++++ F+ SG 
Sbjct: 337  WLSRILMNVEYQIPQSPLLQNS----------RDRFAKGLVELAQDLGANILV-FSMSGT 385

Query: 1562 AARLIAKYRP 1591
             AR IAK+RP
Sbjct: 386  LARRIAKFRP 395

to top

>Q9YEU2:KPYK_AERPE Pyruvate kinase - Aeropyrum pernix|
          Length = 458

 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 65/235 (27%), Positives = 106/235 (45%)
 Frame = +1

Query: 250 KIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAVM 429
           KIV T+GP S S   ++  L  G+ VAR + S G        LE+L+ A +A  K   V 
Sbjct: 6   KIVATVGPSSSSASILAQMLSLGVDVARINASHGGVEQWNSMLESLRRAEEAVGKRVGVA 65

Query: 430 LDTVGPELQVVNKSEVTISLEENESVVLTPHKGQEASSKLLPINFSGLAKAVKPGATIFV 609
           +D  GP ++  N   V   LE+ + V L   +G       +P++     + +  G  + +
Sbjct: 66  VDLEGPRVRTGNSEPV--KLEKGDLVTLGFMEGD------VPVDARQFFETIDEGDIVLL 117

Query: 610 GQYLFTGSETTSVWLEVSEVQGDDVVCVIKNSATLAGSLFTLHCSQIHIDMPTLSDEDKD 789
                   +   + L+V  V+G  V   +     L G    +       D+P LS +D+ 
Sbjct: 118 --------DDGKIILQVESVEGFRVKARVLEGGVL-GPRKGVVVRGKEPDLPPLSAKDRR 168

Query: 790 VMKKWGAPNKIDFLSLSYTRHAEDVRQAREFLSKLGDLSQTLIFAKIENVEVISR 954
            + ++ A   +  + +S+ R AE V + R  + +LG L Q  IFAKIE    +SR
Sbjct: 169 AL-EFFADKGVSHVYVSFARSAEHVEKVRTVVRRLG-LRQARIFAKIEGPSGVSR 221



 Score = 70.5 bits (171), Expect = 4e-11
 Identities = 47/171 (27%), Positives = 88/171 (51%), Gaps = 1/171 (0%)
 Frame = +2

Query: 1082 GLNHFDEILEEADGIILSRGNLGIDLPPEKVFLFQKSALHKCNMAGKPAVV-TRVVDSMT 1258
            G++   EI E +DG+I++RG+LG+    E++   Q+  + +     K  V+ T  + SM 
Sbjct: 218  GVSRIGEIAEASDGVIIARGDLGMHYSLEELPEIQELIVWEARKRYKTVVLATEFLSSMI 277

Query: 1259 DNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYF 1438
            +   PTR+E  D+  AVL  +DA++L  ET  G YPV+++  + +I + A K        
Sbjct: 278  EKPVPTRSEVVDIYQAVLQTADALMLTGETAIGKYPVKSVQWMAKISSRAYK------KL 331

Query: 1439 KRTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRP 1591
              +      P +    +A   V  A  + + +++ ++ +GR A  +A ++P
Sbjct: 332  ATSPPERPRPTSTPYKLALGLVELAESLDSPLVV-YSKTGRFAERLASFKP 381

to top

>Q04668:KPYK_LEIBR Pyruvate kinase - Leishmania braziliensis|
          Length = 91

 Score = 65.5 bits (158), Expect = 1e-09
 Identities = 36/85 (42%), Positives = 51/85 (60%)
 Frame = +1

Query: 202 VSILEPSKPNFFPAMTKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLE 381
           +SI EP +         IV T+GP ++SVEA+   +K+GMSVAR +FS G   YHQ T+ 
Sbjct: 10  LSIFEPLRTT-----GTIVCTIGPSTQSVEALKGLIKSGMSVARMNFSHGSHEYHQTTIN 64

Query: 382 NLKIAIKATKKLCAVMLDTVGPELQ 456
           N++ A        A+ LDT GPE++
Sbjct: 65  NVRQAAAELGVNIAIALDTKGPEIR 89

to top

>P19680:KPYK_SPICI Pyruvate kinase - Spiroplasma citri|
          Length = 192

 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 5/96 (5%)
 Frame = +1

Query: 247 TKIVGTLGPKSRSVEAISACLKAGMSVARFDFSWGDAAYHQETLENLKIAIKATKKLCAV 426
           TKI+ T+GP + S  AI    K GM+  R +FS GD A     +   +       K  +V
Sbjct: 13  TKIITTIGPSTHSPGAIEELFKTGMTTIRLNFSHGDHAEQGARIVWAREVSAKIGKPISV 72

Query: 427 MLDTVGPELQ-----VVNKSEVTISLEENESVVLTP 519
           +LDT GPE+      ++ KS + I  + N S++ +P
Sbjct: 73  LLDTKGPEIHWRIKGLLQKS-LNIYHQMNNSLMFSP 107

to top

>Q9ZKZ0:HLDE_HELPJ Bifunctional protein hldE [Includes: D-beta-D-heptose 7-phosphate|
            kinase - Helicobacter pylori J99 (Campylobacter pylori
            J99)
          Length = 463

 Score = 35.4 bits (80), Expect = 1.3
 Identities = 54/217 (24%), Positives = 82/217 (37%), Gaps = 22/217 (10%)
 Frame = +2

Query: 1085 LNHFDEILEEADGIILSRGNLGI-DLPPEKVFLFQKSALHK---CNMAGKPAVVTRVVDS 1252
            L+   E ++E DG+ILS  N G+ D    +  +   +  HK   C+  GK         S
Sbjct: 128  LDFIAEKIQEIDGVILSDYNKGVLDFELTQTIITLANKHHKLILCDPKGKDYSKY----S 183

Query: 1253 MTDNLRPTRAEATDVANAVLDG----SDAILLGAETLRGLYPVETISTVGRICAEAEKVF 1420
                + P RAE     +  LD     S A+ +  ET     P+ T+S  G    E  ++ 
Sbjct: 184  HASLITPNRAELEQALHLKLDSHANLSKALQILQETYHIAMPLVTLSEQGIAFLEKGELV 243

Query: 1421 NQDLYFKRTVKYVGEPMTHLESIASS-------------AVRAAIKVKASVIICFTSSGR 1561
            N     K      G   T + S+  S             A  AA  V   +     S   
Sbjct: 244  NCPTIAKEVYDVTGAGDTVIASLTLSLLESKSLKEACEFANAAAAVVVGKMGSALASLEE 303

Query: 1562 AARLIAKYRPTMPVLSVVIPRLKTNQLKWSFT-GAFE 1669
             A ++ +  P +  L  ++  L+ NQ K  FT G F+
Sbjct: 304  IALILNQTHPKILPLEKLLETLERNQQKIVFTNGCFD 340

to top

>Q1CT14:HLDE_HELPH Bifunctional protein hldE [Includes: D-beta-D-heptose 7-phosphate|
            kinase - Helicobacter pylori (strain HPAG1)
          Length = 463

 Score = 35.4 bits (80), Expect = 1.3
 Identities = 55/217 (25%), Positives = 85/217 (39%), Gaps = 22/217 (10%)
 Frame = +2

Query: 1085 LNHFDEILEEADGIILS---RGNLGIDLPPEKVFLF-QKSALHKCNMAGKPAVVTRVVDS 1252
            L+ F E ++E DG+ILS   +G L  +L  + + L  Q   L  C+  GK         S
Sbjct: 128  LDFFTEKIQEIDGVILSDYNKGVLDFELTQKMITLANQHHKLILCDPKGKDYSKY----S 183

Query: 1253 MTDNLRPTRAEATDVANAVLDG----SDAILLGAETLRGLYPVETISTVGRICAEAEKVF 1420
                + P RAE     +  LD     S A+ +  ET +   P+ T+S  G    E  ++ 
Sbjct: 184  HASLITPNRAELEHALHLKLDSHANLSKALQILKETYQIAMPLVTLSEQGIAFLEKGELV 243

Query: 1421 NQDLYFKRTVKYVGEPMTHLESIASS-------------AVRAAIKVKASVIICFTSSGR 1561
            N     K      G   T + S+  S             A  AA  V   +     S   
Sbjct: 244  NCPTIAKEVYDVTGAGDTVIASLTLSLLESMSLKDACEFANAAAAVVVGKMGSALASLEE 303

Query: 1562 AARLIAKYRPTMPVLSVVIPRLKTNQLKWSFT-GAFE 1669
             A ++ +  P +  L  ++  L+ +Q K  FT G F+
Sbjct: 304  IALILNQTHPKILPLEKLLETLEHHQQKIVFTNGCFD 340

to top

>Q9BYP8:KR171_HUMAN Keratin-associated protein 17-1 - Homo sapiens (Human)|
          Length = 105

 Score = 33.5 bits (75), Expect = 4.8
 Identities = 18/54 (33%), Positives = 21/54 (38%), Gaps = 4/54 (7%)
 Frame = +1

Query: 1192 CSAQVQHGWKACCCY----SCCGQYDRQPKAYSCGGN*CGKCSAGWQ*CHSPWC 1341
            C  Q Q+  + CCC      CCG          CGG+ CG    G   C S  C
Sbjct: 11   CCTQEQNCCEECCCQPGCCGCCGS------CCGCGGSGCGGSGCGGSCCGSSCC 58

to top

>P25391:LAMA1_HUMAN Laminin subunit alpha-1 precursor - Homo sapiens (Human)|
          Length = 3075

 Score = 33.1 bits (74), Expect = 6.2
 Identities = 20/67 (29%), Positives = 25/67 (37%)
 Frame = -3

Query: 1699 EASNYE*LSCFKCACEAPLQLICF*TRNDNRQDRHGGPVLGN*PCSSSR*GEANDDRSLN 1520
            + S YE   C  C C+    L     ++D   D H G   G  PC     GE  D   L 
Sbjct: 385  KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG 444

Query: 1519 FDSRPHC 1499
            +   P C
Sbjct: 445  YKDYPTC 451

to top

>Q7SAX8:FIP1_NEUCR Pre-mRNA polyadenylation factor fip-1 - Neurospora crassa|
          Length = 423

 Score = 32.7 bits (73), Expect = 8.1
 Identities = 22/86 (25%), Positives = 35/86 (40%), Gaps = 5/86 (5%)
 Frame = +2

Query: 1139 GNLGIDLPPEKVFLFQKSALHKCNMAGKPAVVTRVVDSMTDNLRPTRAEATDVANAVLDG 1318
            G  G +LPP +    +   +      GKP     + + + +N +P R   TD+++    G
Sbjct: 167  GGSGAELPPVRTSKIEVDGIPVYKPVGKPITGVVIDEDLPENDKPWRKPGTDLSDYFNYG 226

Query: 1319 SDAILLG-----AETLRGLYPVETIS 1381
             D           E LRG Y  E I+
Sbjct: 227  FDEFTWALYAQKQEALRGEYNAEAIA 252

to top

>Q6P9Q4:FHOD1_MOUSE FH1/FH2 domain-containing protein 1 - Mus musculus (Mouse)|
          Length = 1197

 Score = 32.7 bits (73), Expect = 8.1
 Identities = 23/61 (37%), Positives = 29/61 (47%)
 Frame = -2

Query: 614 CPTNIVAPGFTALASPEKLIGSNLEEASWPL*GVRTTDSFSSSEIVTSLLFTTCNSGPTV 435
           CP     PG T  ASP   +GS     S P     T  +FSS+   + LL T+ N  PT+
Sbjct: 376 CPVRAPEPGSTGSASP---VGSTPSTGSAP----PTNPAFSSTGPASGLLRTSVNLFPTI 428

Query: 434 S 432
           S
Sbjct: 429 S 429

to top

>Q87UB2:AGUA_PSESM Agmatine deiminase - Pseudomonas syringae pv. tomato|
          Length = 368

 Score = 32.7 bits (73), Expect = 8.1
 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
 Frame = -2

Query: 395 AILRFSSVSWWYAASPHEKSKRATDMPAFRQAEMASTD---RDLGPS 264
           AI RF  V+   +A+ ++ ++   DMP  R  EM+S D   RD GP+
Sbjct: 53  AIARFEPVTVAVSAAQYDNARARLDMPNIRVVEMSSNDAWVRDSGPT 99


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 472,880,824
Number of extensions: 10379777
Number of successful extensions: 25296
Number of sequences better than 10.0: 104
Number of HSP's gapped: 25071
Number of HSP's successfully gapped: 195
Length of query: 899
Length of database: 100,686,439
Length adjustment: 122
Effective length of query: 777
Effective length of database: 67,222,449
Effective search space: 52231842873
Effective search space used: 52231842873
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

to top

full-length cDNA and EST

Clone Information

BLAST Search Result