ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf22l14 |
|---|---|
| Clone Library Name | barley_pub |
>O22928:PUSH_ARATH Putative tRNA pseudouridine synthase - Arabidopsis thaliana| (Mouse-ear cress) Length = 510 Score = 446 bits (1148), Expect = e-124 Identities = 223/439 (50%), Positives = 307/439 (69%), Gaps = 8/439 (1%) Frame = +2 Query: 269 RWESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQK 448 +WES RKK+VV+R+GYVG++YRGLQ QRD TIE LE AI+KAGGI +SNYG L K Sbjct: 56 KWESYRKKKVVIRIGYVGTDYRGLQIQRDDPSIKTIEGELEVAIYKAGGIRDSNYGDLHK 115 Query: 449 VGWERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPA 628 +GW RSSRTDKGVHSLAT ISLKMEIP+ AW+ DP G LA I+ +LP+NI+VFS+LP+ Sbjct: 116 IGWARSSRTDKGVHSLATSISLKMEIPETAWKDDPQGTVLAKCISKHLPENIRVFSVLPS 175 Query: 629 QRSFDVRRECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNYTA 808 R FD RREC R+Y YLLP +++GIK+S +S E++ H+ +FN ILK FEG +PFHNYT Sbjct: 176 NRRFDPRRECTLRKYSYLLPVDVLGIKNSFTSDEIDYHITDFNEILKEFEGEYPFHNYTQ 235 Query: 809 RAKYRKVLAGAHRRAKETSTAAHSIPSEMVADQSTSSADDEYLNFPSILDSSAREDNCKM 988 R++YR+ + ++ K+ + P + A +S ++ ++ E+ ++ Sbjct: 236 RSRYRR---KSEQKIKQRNGRPPREPKSIKASESEFREENH-------IEIGEEEEEKEV 285 Query: 989 D--------NPELPQSRVQIQARWLHEPNDNDRLSASHFRDILTCSCGELQSSSGVQFVE 1144 D P+ S+V +A+WL+EP++ D++S +HFR + C G+L++S G FVE Sbjct: 286 DGESDEHVVTPDSDNSQVYSRAKWLYEPDETDKISGAHFRKVFRCRSGKLENSLGFGFVE 345 Query: 1145 LTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVLPIAPSEVLILRDNSF 1324 ++I G SFMLHQIRKM+GTAVAVKR LLP+DII+LSL KF+RIVLP+APSEVLILR NSF Sbjct: 346 ISIWGESFMLHQIRKMIGTAVAVKRELLPRDIIRLSLNKFTRIVLPLAPSEVLILRGNSF 405 Query: 1325 CTRNKQGSIVRPGMQSINESEEIKKGVMEFYKVALVPELAKFLDESLPPWQEWVENLDHF 1504 R RPGM++ ESEE++K + EFY+ +VP+++ FLD PW+EWV++LD Sbjct: 406 EVRRLP---ERPGMEATGESEEVEKEIEEFYRAVMVPQVSIFLDSEKSPWKEWVDHLDRN 462 Query: 1505 TSIPDSQLDEVRTAYRAWK 1561 + D +L++VR + WK Sbjct: 463 DGLIDEELEDVRKGWEEWK 481
>Q6FV05:PUS1_CANGA tRNA pseudouridine synthase 1 - Candida glabrata (Yeast) (Torulopsis| glabrata) Length = 549 Score = 112 bits (280), Expect = 5e-24 Identities = 117/438 (26%), Positives = 198/438 (45%), Gaps = 22/438 (5%) Frame = +2 Query: 287 KKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERS 466 K++V + +GY G+ Y G+Q + TIE+ L A AG I ++N L+K + R+ Sbjct: 86 KRKVAVMIGYCGTGYHGMQYNPP---NPTIEAALFKAFVDAGAISKANSNDLKKNNFMRA 142 Query: 467 SRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 +RTDKGVH+ +ISLKM I +DP+ + + IN+NLP+ I+++ I ++FD Sbjct: 143 ARTDKGVHAGGNLISLKMII------EDPE---IMDKINANLPEGIRIWDIERVNKAFDC 193 Query: 647 RRECLYREYFYLLPA-EIIGIK-SSCSSGEVEEHLIEFNNIL-KGFEGNHPFHNYTARAK 817 R+ C R Y YLLP +IG K + + ++E E +L + E + N+ A AK Sbjct: 194 RKMCSSRWYEYLLPTYSLIGPKPGTILNNDIESSKTELPGVLDEDLESKEFWENFEAAAK 253 Query: 818 YRKVLAGAHRRAKETSTAAHSIPSEMVADQSTSSADDEYLNFPSILDSSAREDNCKMDNP 997 KE + P E+ A + S E + L ++ ++N Sbjct: 254 ------------KEFT------PEEIAAIKDYSPPPREEFDDQEELYQKVKQWKL-LENT 294 Query: 998 ELPQSRVQIQARWLHEPNDNDRLSASHFRDILTCSCGELQSSSGVQF------------- 1138 Q R+ N L A +F + E + S ++F Sbjct: 295 HRRQYRISEMKLNKFRAAMNQYLGAHNFHNFTLGK--EFKDPSAIRFMKEIKVSDPFVIG 352 Query: 1139 ------VELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVLPIAPSEV 1300 V + I G SFMLHQIRKM+ A + R P + I + +I +P AP+ Sbjct: 353 DAKAEWVSIKIHGQSFMLHQIRKMISMATLIARCGTPVERISQAFGP-QKINIPKAPALG 411 Query: 1301 LILRDNSFCTRNKQGSIVRPGMQSINESEEIKKGVMEFYKVALVPELAKFLDESLPPWQE 1480 L+L F + NK+ + + G + I+ S+ +K ++ +K+ + + + S + Sbjct: 412 LLLEAPVFESYNKR--LEKFGYKPIDFSKYQEK--VDAFKMKHIYDKIYAEEVSDNVFNA 467 Query: 1481 WVENLDHFTSIPDSQLDE 1534 + +D F + +Q +E Sbjct: 468 FFSYIDSFNKVTGAQTEE 485
>Q6CWQ8:PUS1_KLULA tRNA pseudouridine synthase 1 - Kluyveromyces lactis (Yeast) (Candida| sphaerica) Length = 553 Score = 112 bits (279), Expect = 7e-24 Identities = 101/352 (28%), Positives = 163/352 (46%), Gaps = 11/352 (3%) Frame = +2 Query: 287 KKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERS 466 K++V + +GY G+ Y G+Q + TIE L A +AG I ++N L+K G++R+ Sbjct: 98 KRKVAVMIGYCGTGYHGMQYNPP---NDTIEKELFEAFVRAGAISKANSTDLKKNGFQRA 154 Query: 467 SRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 +RTDKGVH+ +ISLK+ I +DP+ + IN+ LPD I+V+ I ++FD Sbjct: 155 ARTDKGVHAGGNVISLKLII------EDPE---VKEKINNELPDQIRVWDISRVNKAFDC 205 Query: 647 RRECLYREYFYLLPA-EIIGIK-SSCSSGEVEEHLIEFNNILK-GFEGNHPFHNYTARAK 817 R+ C R Y YLLP +IG K S+ E+E E N+++ E + ++ A+ Sbjct: 206 RKMCSSRWYEYLLPTYSLIGPKPSTYLYNEIEASKKEIPNVIQDDVESAQFWEAFSTEAE 265 Query: 818 YRKVLAGAHRRAKETSTAAHSIPSEMVADQSTSSADDEYLNFPSILDSSAREDNCKMDNP 997 +K T I + ++ S ++ Y + A + Sbjct: 266 -----------SKFTKEELEEIAAFVMPKDSFDENNETYQKSKAFKKLEAEHKRAYRISK 314 Query: 998 E--------LPQSRVQIQARWLHEPNDNDRLSASHFRDILTCSCGELQSSSGVQFVELTI 1153 E L Q D + SA F +T S + + ++V + I Sbjct: 315 ERLDRFRSALKQYEGTFNFHNFTLGKDFNDPSAKRFMKQITVSEPFVIGEAKTEWVSIKI 374 Query: 1154 CGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVLPIAPSEVLIL 1309 G SFMLHQIRKM+ A + R P + I+ + + +I +P AP+ L+L Sbjct: 375 HGQSFMLHQIRKMISMATLITRCFSPLERIRQAYGQ-EKINIPKAPALGLLL 425
>Q12211:PUS1_YEAST tRNA pseudouridine synthase 1 - Saccharomyces cerevisiae (Baker's| yeast) Length = 544 Score = 107 bits (266), Expect = 2e-22 Identities = 107/361 (29%), Positives = 161/361 (44%), Gaps = 9/361 (2%) Frame = +2 Query: 287 KKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERS 466 K++V + VGY G+ Y G+Q + TIES L A +AG I + N L+K G+ R+ Sbjct: 74 KRKVAVMVGYCGTGYHGMQYNPP---NPTIESALFKAFVEAGAISKDNSNDLKKNGFMRA 130 Query: 467 SRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 +RTDKGVH+ +ISLKM I +DPD + IN LP+ I+V+ I ++FD Sbjct: 131 ARTDKGVHAGGNLISLKMII------EDPD---IKQKINEKLPEGIRVWDIERVNKAFDC 181 Query: 647 RRECLYREYFYLLPA-EIIGIK-SSCSSGEVEEHLIEFNNIL-KGFEGNHPFHNYTARAK 817 R+ C R Y YLLP +IG K S ++EE E +L + E + + Sbjct: 182 RKMCSSRWYEYLLPTYSLIGPKPGSILYRDIEESKTELPGVLDEDLESKEFWEEF----- 236 Query: 818 YRKVLAGAHRRAKETSTAAHSIP---SEMVADQSTSSADDEYLNFPSILDSSAREDNCKM 988 K A +E +P E ++ +Y + R K+ Sbjct: 237 --KKDANEKFSTEEIEAILAYVPPARDEFDINEELYQKVKKYKQLENAHRRRYRISAAKL 294 Query: 989 DNPELPQSRVQIQARWLHE---PNDNDRLSASHFRDILTCSCGELQSSSGVQFVELTICG 1159 S+ + A H D SA F + S + + +++ + I G Sbjct: 295 AKFRASTSQ-YLGAHNFHNFTLGKDFKEPSAIRFMKDIKVSDPFVIGDAQTEWISIKIHG 353 Query: 1160 VSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVLPIAPSEVLILRDNSFCTRNK 1339 SFMLHQIRKMV A + R P + I + + +I +P AP+ L+L F NK Sbjct: 354 QSFMLHQIRKMVSMATLITRCGCPVERISQAYGQ-QKINIPKAPALGLLLEAPVFEGYNK 412 Query: 1340 Q 1342 + Sbjct: 413 R 413
>Q6CC39:PUS1_YARLI tRNA pseudouridine synthase 1 - Yarrowia lipolytica (Candida| lipolytica) Length = 528 Score = 106 bits (265), Expect = 3e-22 Identities = 105/389 (26%), Positives = 178/389 (45%), Gaps = 19/389 (4%) Frame = +2 Query: 287 KKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERS 466 K++V +GY G+ Y G+Q TIE + A KAG I ++N +K + R+ Sbjct: 84 KRKVACMIGYCGTGYHGMQLNPP---QKTIEGDIFQAFVKAGAISQNNADDPKKSAFMRA 140 Query: 467 SRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 +RTDKGVH+ +ISLKM I D + INS+LP+ ++V+ + ++F+ Sbjct: 141 ARTDKGVHAAGNVISLKMIIEDE---------NIVEKINSHLPEQLRVWGVSRTNKAFEC 191 Query: 647 RRECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNYTARA---- 814 R+ C R Y YL+P + G V + + EG + + A Sbjct: 192 RKLCSSRVYEYLMPTYSF---LNPRPGTVMSEKLLKDGTSPDEEGKKYWESVAADLESQG 248 Query: 815 ----KYRKVLAGAHRRAKETSTAAHSIPSEMVADQSTSSADDEYLNFPSILDSSAREDNC 982 ++ K + +ET A SE+ D T +A E + ++ RE+ Sbjct: 249 VSYDEWMKRACIDEIKGEETKEVAE---SEVKTDSKTDAATLEKI---KAVERRHREE-F 301 Query: 983 KMDNPELPQSRVQIQARWLHEPNDNDR--------LSASHFRDILTCSCGELQSSSGVQF 1138 ++ L + R ++ ++E N S R + + +C + G ++ Sbjct: 302 RISGERLAKIREILK---IYEGTHNFHNFTLGKAFKDPSAMRTMKSLTCSDPFLIDGTEW 358 Query: 1139 VELTICGVSFMLHQIRKMVG-TAVAVKRGLLPKDIIKLSLAKFSRIVLPIAPSEVLILRD 1315 V + I G SFMLHQIRKM+ A++V+ P+ +I + K +RI +P AP+ L+L Sbjct: 359 VSIKIHGQSFMLHQIRKMISMVALSVRCNADPQKLIPQTFEK-ARINIPKAPALGLLLER 417 Query: 1316 NSFCTRNK--QGSIVRPGMQSINESEEIK 1396 + + NK QG R G+ N +++I+ Sbjct: 418 PVYDSYNKKLQGEFGREGVHFDNWNDQIE 446
>Q755C8:PUS1_ASHGO tRNA pseudouridine synthase 1 - Ashbya gossypii (Yeast) (Eremothecium| gossypii) Length = 528 Score = 102 bits (253), Expect = 7e-21 Identities = 102/373 (27%), Positives = 170/373 (45%), Gaps = 9/373 (2%) Frame = +2 Query: 251 AGSGGMRWESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESN 430 AG+ + K++V + VGY G+ Y G+Q + TIE+ L A KAG I +N Sbjct: 54 AGTSEEKEARLPKRKVAVMVGYCGTGYHGMQYNPP---NRTIEAELFEAFVKAGAISRAN 110 Query: 431 YGKLQKVGWERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKV 610 L+K G+ R++RTDKGVH+ +ISLK+ I D A+ + IN +LP I+V Sbjct: 111 STDLKKNGFMRAARTDKGVHAGGNVISLKLIIEDP---------AIKDKINEHLPPGIRV 161 Query: 611 FSILPAQRSFDVRRECLYREYFYLLPA-EIIGIKSSCSSGEVEEHLIEFNNILKGFEGNH 787 + I ++FD R+ C R Y YLLP IG K + E E + + Sbjct: 162 WGISRVNKAFDCRKLCGSRWYEYLLPTYSFIGPKPNTYLARTIEQCGE----AASEKPDR 217 Query: 788 PFHNYTARAKYRKVLAGAHRRAKETSTAAHSIPSEMVADQSTSSADDEYLNFPSILDSSA 967 + +RK + + ++ + + PS+ D++ S + + + +A Sbjct: 218 DQESLDFWEAFRKAVDEKFTQEEQDAIVNYVAPSKEDFDEN-SGLYQKVKQYKQM--ENA 274 Query: 968 REDNCKMDNPELPQSRVQIQARWLHEPNDNDRLSASHFRD--------ILTCSCGELQSS 1123 + ++ + +L + R + ++L N ++ F+D +T S + Sbjct: 275 HRRSYRVSSAKLARFR-EAMKQYLGPHNFHNYTLGKDFKDPSTVRFMKDITVSRPFVIGE 333 Query: 1124 SGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVLPIAPSEVL 1303 ++V + I G SFMLHQIRKM+ A V R + I S +I +P AP+ L Sbjct: 334 MKTEWVSIKIHGQSFMLHQIRKMISMATLVARCNCSPERIAQSYGP-QKINIPKAPALGL 392 Query: 1304 ILRDNSFCTRNKQ 1342 +L + NK+ Sbjct: 393 LLESPVYEGYNKR 405
>Q9Y606:TRUA_HUMAN tRNA pseudouridine synthase A - Homo sapiens (Human)| Length = 427 Score = 97.1 bits (240), Expect = 2e-19 Identities = 61/191 (31%), Positives = 98/191 (51%), Gaps = 4/191 (2%) Frame = +2 Query: 251 AGSGGMRWESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESN 430 +G R E K+++VL + Y G Y G+Q+ S TIE L SA+ ++G I E++ Sbjct: 71 SGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENH 130 Query: 431 YGKLQKVGWERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKV 610 ++K+ ++R +RTDKGV + ++SLK+ + D EK INS+LP +I++ Sbjct: 131 GEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEK----------INSHLPSHIRI 180 Query: 611 FSILPAQRSFDVRRECLYREYFYLLPAEIIGIKSSCSSGEV----EEHLIEFNNILKGFE 778 + F+ + C R Y YLLP K E E L + N +L ++ Sbjct: 181 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK 240 Query: 779 GNHPFHNYTAR 811 G H FHN+T++ Sbjct: 241 GTHNFHNFTSQ 251 Score = 52.8 bits (125), Expect = 5e-06 Identities = 31/87 (35%), Positives = 48/87 (55%) Frame = +2 Query: 1082 RDILTCSCGELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAK 1261 R IL C E G++F + + G SFM+HQIRKMVG VA+ +G P+ +++ S Sbjct: 261 RYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGT 320 Query: 1262 FSRIVLPIAPSEVLILRDNSFCTRNKQ 1342 ++ +P AP L+L F N++ Sbjct: 321 -EKVDVPKAPGLGLVLERVHFEKYNQR 346
>O94295:PUS2_SCHPO tRNA pseudouridine synthase 2 - Schizosaccharomyces pombe (Fission| yeast) Length = 451 Score = 96.7 bits (239), Expect = 3e-19 Identities = 100/417 (23%), Positives = 188/417 (45%), Gaps = 26/417 (6%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 + + K R+++ +GY G Y G+Q L TIE + A+ K G L++N + + Sbjct: 34 KESNKVRIIILLGYSGYGYHGIQINNPLK---TIEGDVV-AVLKKLGYLKTNNIDAEHLC 89 Query: 455 WERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQR 634 R++RTDKGVH+L +ISL + + +K D L +N L I+V+S+ PA + Sbjct: 90 IARAARTDKGVHTLRNLISLNLFV-----DKPLDISLLKTELNEALCSQIRVWSVFPAPK 144 Query: 635 SFDVRRECLYREYFYLLPA-EIIGIKSSCS-------------SGEVEEHLIEFNNILKG 772 F+ R C R Y YL+P+ ++ K SC E+E +L+ N L Sbjct: 145 YFNPRISCESRTYEYLIPSFALLPPKPSCPLFKKMQKNLSRKLDNELERNLVYSMNDLIS 204 Query: 773 FEGNHPFHNYTARAKYRKVLAGAHRRAKETSTAAHSIPSE------------MVADQSTS 916 F T + K +++ + +T+ A + P + ++ Q+ Sbjct: 205 FWN-------TVKLKQKEI-----QEMFDTNKDAFTNPFKGMFYEKPIPAGIVIPPQAKL 252 Query: 917 SADDEYLNFPSILDSSAREDNCKMDNPELPQSRVQIQARWLHEPNDNDRLSASHFRDILT 1096 + + ++ +ED K+ L + + + + + +D S S++R I + Sbjct: 253 KKALKQAEYYCYMNYRIKEDRLKVLQQLL--KKYEGRHNFHNFTVTDDSTSPSNYRFIES 310 Query: 1097 CSCGELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIV 1276 +CG +++ +TI G SFML+QIRKM+ + + R P +I + + Sbjct: 311 VTCGTPFVYENWEWIPVTIKGNSFMLNQIRKMMAHVLMIIRSCAPTGLIDKAFDPNITMN 370 Query: 1277 LPIAPSEVLILRDNSFCTRNKQGSIVRPGMQSINESEEIKKGVMEFYKVALVPELAK 1447 + +P VL+L+D F + N V G++ I + + ++ ++ + P++ K Sbjct: 371 ISKSPGHVLLLKDIKFSSYNDS---VTDGLEKI-QFDCFEEDILSLKIKTIYPDIIK 423
>Q59S63:PUS1_CANAL tRNA pseudouridine synthase 1 - Candida albicans (Yeast)| Length = 450 Score = 96.3 bits (238), Expect = 4e-19 Identities = 88/312 (28%), Positives = 152/312 (48%), Gaps = 17/312 (5%) Frame = +2 Query: 440 LQKVGWERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSI 619 L+K G++R++RTDKGVH+ +ISLKM I +DP+ + N IN LP I+++ I Sbjct: 36 LKKSGFQRAARTDKGVHAAGNVISLKMII------EDPE---IINKINDLLPKQIRIWGI 86 Query: 620 LPAQRSFDVRRECLYREYFYLLPA-EIIGIK-SSCSSGEVEEHLIEFNNILKGFEGNHPF 793 A + FD R+ C R Y YLLP ++ K S S V+E +E ++ FE + Sbjct: 87 QRATKGFDCRKCCSSRIYEYLLPTFSLLPPKPKSVLSELVKEKELENPDL---FEDDQEG 143 Query: 794 HNYTARAKYRKVLAGAHRRAKETSTAAHSIPSEMVADQSTSSADDE-----YLNFPSILD 958 ++ K + + +G + ++ T+++ + Q AD+E L+F ++ Sbjct: 144 IDWWENVKSKILASGITQEQIDSITSSYDEQQQQQHHQQQQQADEEERDISELSFTKLIK 203 Query: 959 SSAREDNCKMDNPELPQSRVQ----IQARWLHEPNDNDRLSASHFRD------ILTCSCG 1108 +N + + SR+Q + ++ N ++ F+D ++ Sbjct: 204 QIKTIENQSRRSYRISSSRLQHFREVMKQYEGTHNFHNFTVGKPFKDTSANRFMIKTIVS 263 Query: 1109 ELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVLPIA 1288 + G +++ + I G SFMLHQIRKM+ A V R LP II + + ++I +P A Sbjct: 264 DPFVIEGTEWISIKIHGQSFMLHQIRKMIAMAALVVRLSLPCGIIN-NFFQSTKINIPKA 322 Query: 1289 PSEVLILRDNSF 1324 P+ L+L + F Sbjct: 323 PALGLLLENPVF 334
>O94396:PUS1_SCHPO tRNA pseudouridine synthase 1 - Schizosaccharomyces pombe (Fission| yeast) Length = 534 Score = 95.5 bits (236), Expect = 7e-19 Identities = 105/412 (25%), Positives = 170/412 (41%), Gaps = 62/412 (15%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 E K++V VGY GS Y G+Q TIE L A KAG + N +KV Sbjct: 39 EKKPKRKVACLVGYCGSGYHGMQLNPP---SKTIEGDLFDAFVKAGAVSSYNADDPKKVA 95 Query: 455 WERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQR 634 R++RTDKGVH+ +ISLK+ + D L +N +LP +I+++ ++ Sbjct: 96 LARAARTDKGVHAAGNVISLKLIMEDE---------KLIEKVNEHLPPSIRLWDVIRTIN 146 Query: 635 SFDVRRECLYREYFYLL---------PAEIIG---IKSSCSSGEV--EEHLIEFNNILKG 772 SF+ R C R Y Y++ P+ I+G +K+S E +E++ + + L Sbjct: 147 SFNPRTYCESRIYEYMVPTYAFVPPKPSSILGNCIMKNSPMPAEPINKENINQLSRSLFY 206 Query: 773 FEGNHPFHNYTARAK------------------YRKVLAGAHRRAKETSTAAHSIPSEMV 898 EG + +Y AK R A A+ + S A S + Sbjct: 207 EEGKEFWDDYDIAAKEILSLYEQDPEGFVNPYSKRGAAALANSENNKGSEAGVSAKTNPD 266 Query: 899 ADQSTSSADDEYLNFPSILDSSARE---------------DNCKMDNPELPQSRVQIQAR 1033 D +S+ +E+L S+ D SA + K+ N + R+ + Sbjct: 267 MDSDSSAIVNEFLKPDSVEDESAGSKIDPSYRLERALKHIEVLKLKNYRISADRLSVIRE 326 Query: 1034 WLHEPNDNDRLSASHFRDILTCSCGELQSSSGV---------------QFVELTICGVSF 1168 L N + +F + ++S+ V +++ + G SF Sbjct: 327 TL-----NQYVGVHNFHNFTVGQAFHQKNSNRVIRSFTASDPFMIGDTEWISCKVHGQSF 381 Query: 1169 MLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVLPIAPSEVLILRDNSF 1324 MLHQIRKM+ A+ V R P + I+ + K ++I +P P L+L F Sbjct: 382 MLHQIRKMIALAILVVRTGCPVERIQDAFKK-TKINIPKGPGFGLLLESPFF 432
>Q9WU56:TRUA_MOUSE tRNA pseudouridine synthase A - Mus musculus (Mouse)| Length = 423 Score = 94.7 bits (234), Expect = 1e-18 Identities = 63/209 (30%), Positives = 101/209 (48%), Gaps = 23/209 (11%) Frame = +2 Query: 254 GSGGMRWESTR-------------------KKRVVLRVGYVGSEYRGLQKQRDLSGDSTI 376 G GG WE T K+++VL + Y G Y G+Q+ S TI Sbjct: 49 GRGGWVWEETEHPAKRVKGGEDEEPPRKLPKRKIVLLMAYSGKGYHGMQRNLGSSQFRTI 108 Query: 377 ESVLESAIFKAGGILESNYGKLQKVGWERSSRTDKGVHSLATMISLKMEIPDRAWEKDPD 556 E L SA+ +AG I E++ ++K+ ++R +RTDKGV + ++SLK+ + D +K Sbjct: 109 EDDLVSALVQAGCIPENHGTDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILDK--- 165 Query: 557 GIALANFINSNLPDNIKVFSILPAQRSFDVRRECLYREYFYLLPAEIIGIKSSCSSGE-- 730 INS+LP +I++ + F+ + +C R Y Y+LP K E Sbjct: 166 -------INSHLPSHIRILGLKRVTGGFNSKNKCDARTYCYMLPTFAFAHKDRDVQDESY 218 Query: 731 --VEEHLIEFNNILKGFEGNHPFHNYTAR 811 E L + N +L ++G H FHN+T++ Sbjct: 219 RLSAETLQQVNRLLACYKGTHNFHNFTSQ 247 Score = 53.5 bits (127), Expect = 3e-06 Identities = 31/87 (35%), Positives = 49/87 (56%) Frame = +2 Query: 1082 RDILTCSCGELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAK 1261 R IL C E G++F + + G SFM+HQIRKMVG VA+ +G P+ +++ S + Sbjct: 257 RYILEMYCEEPFVREGLEFAVIKVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGE 316 Query: 1262 FSRIVLPIAPSEVLILRDNSFCTRNKQ 1342 ++ +P AP L+L F N++ Sbjct: 317 -EKVDVPKAPGLGLVLERVHFEKYNQR 342
>Q4KM92:TRUA_RAT tRNA pseudouridine synthase A - Rattus norvegicus (Rat)| Length = 393 Score = 94.4 bits (233), Expect = 2e-18 Identities = 63/209 (30%), Positives = 101/209 (48%), Gaps = 23/209 (11%) Frame = +2 Query: 254 GSGGMRWESTR-------------------KKRVVLRVGYVGSEYRGLQKQRDLSGDSTI 376 G GG WE T K+++VL + Y G Y G+Q+ S TI Sbjct: 19 GRGGWVWEETEHPAKRVKGGEDEEPPRKLPKRKIVLLMAYSGKGYHGMQRNLGSSQFRTI 78 Query: 377 ESVLESAIFKAGGILESNYGKLQKVGWERSSRTDKGVHSLATMISLKMEIPDRAWEKDPD 556 E L SA+ +AG I E++ ++K+ ++R +RTDKGV + ++SLK+ + D +K Sbjct: 79 EDDLVSALVQAGCIPENHGTDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILDK--- 135 Query: 557 GIALANFINSNLPDNIKVFSILPAQRSFDVRRECLYREYFYLLPAEIIGIKSSCSSGE-- 730 INS+LP +I++ + F+ + +C R Y Y+LP K E Sbjct: 136 -------INSHLPSHIRILGLKRVTGGFNSKNKCDARTYCYMLPTFAFAHKDRDVQDESY 188 Query: 731 --VEEHLIEFNNILKGFEGNHPFHNYTAR 811 E L + N +L ++G H FHN+T++ Sbjct: 189 RLSAETLQQVNRLLGCYKGTHNFHNFTSQ 217 Score = 53.5 bits (127), Expect = 3e-06 Identities = 31/87 (35%), Positives = 49/87 (56%) Frame = +2 Query: 1082 RDILTCSCGELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAK 1261 R IL C E G++F + + G SFM+HQIRKMVG VA+ +G P+ +++ S + Sbjct: 227 RYILEMYCEEPFVREGLEFAVIKVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGE 286 Query: 1262 FSRIVLPIAPSEVLILRDNSFCTRNKQ 1342 ++ +P AP L+L F N++ Sbjct: 287 -EKVDVPKAPGLGLVLERVHFEKYNQR 312
>P53167:PUS2_YEAST tRNA pseudouridine synthase 2 - Saccharomyces cerevisiae (Baker's| yeast) Length = 370 Score = 68.9 bits (167), Expect = 7e-11 Identities = 43/131 (32%), Positives = 67/131 (51%) Frame = +2 Query: 308 VGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDKGV 487 +GY GS Y G+Q TIE + + +F G I E N +K + ++RTDKGV Sbjct: 3 LGYCGSGYYGMQYNPP---HKTIEGEILTKLFDVGAISEENSLAPKKNSFMAAARTDKGV 59 Query: 488 HSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECLYR 667 H++ ++SLK+ + + K +N+ LP I+V+ I P + F+ R C R Sbjct: 60 HAMLNLLSLKITLREDTVAK----------LNAALPPEIRVWGIQPVNKKFNARSACDSR 109 Query: 668 EYFYLLPAEII 700 Y YL+P I+ Sbjct: 110 WYQYLIPEFIL 120 Score = 43.5 bits (101), Expect = 0.003 Identities = 28/70 (40%), Positives = 40/70 (57%) Frame = +2 Query: 1115 QSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVLPIAPS 1294 Q+S G ++ + I G SFMLHQIR+MV AV R LP +I++ R +P AP+ Sbjct: 241 QASPG--WICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPA 298 Query: 1295 EVLILRDNSF 1324 + L+L F Sbjct: 299 QGLLLEGPVF 308
>Q8TWZ3:TRUA_METKA tRNA pseudouridine synthase A - Methanopyrus kandleri| Length = 256 Score = 62.8 bits (151), Expect = 5e-09 Identities = 47/131 (35%), Positives = 66/131 (50%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 RV LRV Y GS Y G Q Q D+ TIE L A+ + G L+ VG+ +SR Sbjct: 2 RVALRVAYDGSRYHGFQYQPDVP---TIEGALRKALSELG---------LELVGY--ASR 47 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD G H+ ++ + E DP+ +A + IN+ LP +I+V + FD RR Sbjct: 48 TDAGAHARYQVVVV---------EGDPE-LAQPDPINARLPKDIRVIAKTEVHEEFDPRR 97 Query: 653 ECLYREYFYLL 685 + L +EY Y L Sbjct: 98 DALRKEYRYFL 108
>Q9JI38:PUS3_MOUSE tRNA pseudouridine synthase 3 - Mus musculus (Mouse)| Length = 481 Score = 62.0 bits (149), Expect = 8e-09 Identities = 49/173 (28%), Positives = 80/173 (46%), Gaps = 12/173 (6%) Frame = +2 Query: 287 KKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERS 466 ++ V L++ Y+G Y+G Q + S +TIE L A+ K ++ES Q + R Sbjct: 63 RRHVALKIAYLGWGYQGFASQENTS--NTIEEKLFEALTKTR-LVESR----QTSNYHRC 115 Query: 467 SRTDKGVHSLATMISLKM--------EIPDRAWEKDPDGIA----LANFINSNLPDNIKV 610 RTDKGV + +ISL + + D + + D +A + +N LP +I+V Sbjct: 116 GRTDKGVSAFGQVISLDLRSQFPTSRDSEDSNLKHEADDLAKEIRYTHILNRVLPADIRV 175 Query: 611 FSILPAQRSFDVRRECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILK 769 + P + SF R CL R Y Y P + I + + + +F N+ K Sbjct: 176 LAWAPVEPSFSARFSCLERTYRYFFPRADLDIATMNYAAQKYVGTHDFRNLCK 228
>P31115:PUS3_YEAST tRNA pseudouridine synthase 3 - Saccharomyces cerevisiae (Baker's| yeast) Length = 442 Score = 61.6 bits (148), Expect = 1e-08 Identities = 49/186 (26%), Positives = 87/186 (46%), Gaps = 7/186 (3%) Frame = +2 Query: 296 VVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRT 475 + LR Y+G Y GL Q++ + T+E + A+ K + LQ + R RT Sbjct: 94 IALRFAYLGWNYNGLAVQKEYTPLPTVEGTILEAMNKCKLVPSM---VLQDYKFSRCGRT 150 Query: 476 DKGVHSLATMISLKM--EIPDRAWEKDPDG----IALANFINSNLPDNIKVFSI-LPAQR 634 DKGV ++ +ISL++ + D ++DP I + +N LPD+I++ ++ L Sbjct: 151 DKGVSAMNQVISLEVRSNLTDEE-QRDPTNDSREIPYVHVLNQLLPDDIRISAVCLRPPP 209 Query: 635 SFDVRRECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNYTARA 814 +FD R C++R Y Y+ + + I+ + +F N K +G+ N+ Sbjct: 210 NFDARFSCVHRHYKYIFNGKNLNIEKMSKAASYFVGERDFRNFCK-LDGSKQITNFKRTI 268 Query: 815 KYRKVL 832 K+L Sbjct: 269 ISSKIL 274
>Q3SX07:PUS3_BOVIN tRNA pseudouridine synthase 3 - Bos taurus (Bovine)| Length = 481 Score = 60.8 bits (146), Expect = 2e-08 Identities = 53/188 (28%), Positives = 79/188 (42%), Gaps = 17/188 (9%) Frame = +2 Query: 287 KKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERS 466 ++ V L++ Y+G Y+G Q + S +TIE L A+ K ++E+ Q + R Sbjct: 62 QRHVALKIAYLGWGYQGFASQENTS--NTIEEKLFEALTKTR-LVENR----QTSNYHRC 114 Query: 467 SRTDKGVHSLATMIS-----------------LKMEIPDRAWEKDPDGIALANFINSNLP 595 RTDKGV + +IS LK E+ D A E I + +N LP Sbjct: 115 GRTDKGVSAFGQVISLDLRSHIPKGRDSEHFNLKNEVNDVATE-----IRYTHILNRVLP 169 Query: 596 DNIKVFSILPAQRSFDVRRECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILKGF 775 +I+V + P + SF R CL R Y Y P + I + N + + Sbjct: 170 PDIRVLAWAPVETSFSARFSCLERTYRYFFPRANLDI-------------VTMNYAAQKY 216 Query: 776 EGNHPFHN 799 G H F N Sbjct: 217 VGTHDFRN 224
>Q9BZE2:PUS3_HUMAN tRNA pseudouridine synthase 3 - Homo sapiens (Human)| Length = 481 Score = 60.5 bits (145), Expect = 2e-08 Identities = 48/173 (27%), Positives = 79/173 (45%), Gaps = 12/173 (6%) Frame = +2 Query: 287 KKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERS 466 ++ V LR+ Y+G Y+G Q + + +TIE L A+ K ++ES Q + R Sbjct: 62 RRHVALRIAYMGWGYQGFASQENTN--NTIEEKLFEALTKTR-LVESR----QTSNYHRC 114 Query: 467 SRTDKGVHSLATMIS--LKMEIPDRAWEKD----------PDGIALANFINSNLPDNIKV 610 RTDKGV + +IS L+ + P +D + I + +N LP +I++ Sbjct: 115 GRTDKGVSAFGQVISLDLRSQFPRGRDSEDFNVKEEANAAAEEIRYTHILNRVLPPDIRI 174 Query: 611 FSILPAQRSFDVRRECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILK 769 + P + SF R CL R Y Y P + I + + + +F N+ K Sbjct: 175 LAWAPVEPSFSARFSCLERTYRYFFPRADLDIVTMDYAAQKYVGTHDFRNLCK 227
>O26928:TRUA_METTH tRNA pseudouridine synthase A - Methanobacterium| thermoautotrophicum Length = 275 Score = 59.7 bits (143), Expect = 4e-08 Identities = 52/175 (29%), Positives = 75/175 (42%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 +++ L+V Y+G+ Y G Q+Q D+ T+E L A+ AG I + + Q G Sbjct: 2 RKIALKVAYIGTNYHGFQRQPDV---PTVEGKLLEALEGAGIIEDPKRARFQIAG----- 53 Query: 470 RTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVR 649 RTD+GVH+L +S E N IN LP +I+V + F VR Sbjct: 54 RTDRGVHALGNFVSFFTEEDIH-----------VNQINDLLPRDIRVLAWASVMYPFKVR 102 Query: 650 RECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNYTARA 814 L R Y Y+L E + S E H F G H F N++ R+ Sbjct: 103 YP-LERHYRYILHRE--ESMDTYSMAEAAAH----------FRGTHDFSNFSRRS 144
>Q8PWT1:TRUA_METMA tRNA pseudouridine synthase A - Methanosarcina mazei| (Methanosarcina frisia) Length = 269 Score = 57.8 bits (138), Expect = 2e-07 Identities = 42/134 (31%), Positives = 65/134 (48%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 RV L++ Y+G+E+ G Q Q + T+E L A+ I+ES + + + R Sbjct: 2 RVALKLAYIGTEFHGSQIQPSVE---TVEKELFKALRNLR-IIESP----KSANYICAGR 53 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH+L +I A++ D +A+ INS LP I V++ FD RR Sbjct: 54 TDAGVHALGQVI---------AFDTDRPNLAIPRIINSGLPPTIWVWAHAEVPYDFDARR 104 Query: 653 ECLYREYFYLLPAE 694 + R Y Y++ E Sbjct: 105 HAVSRHYRYVISGE 118
>Q8CXP1:TRUA_OCEIH tRNA pseudouridine synthase A - Oceanobacillus iheyensis| Length = 253 Score = 57.0 bits (136), Expect = 3e-07 Identities = 38/134 (28%), Positives = 65/134 (48%), Gaps = 2/134 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 +R+ V Y GS++ G Q Q D T++ VLE A++ N K + + + S Sbjct: 2 ERLKCTVSYDGSDFAGFQVQPD---HRTVQGVLEKALY--------NMHKGKSIRIQASG 50 Query: 470 RTDKGVHSLATMISLK--MEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH++ +I +EIP+R W++ +N+ LPD++++ + F Sbjct: 51 RTDTGVHAVGQVIHFDSPLEIPERNWKQA---------LNTLLPDDVRIQKVEKKTEEFH 101 Query: 644 VRRECLYREYFYLL 685 R +EY Y + Sbjct: 102 ARYSVKEKEYHYFV 115
>Q8TU65:TRUA_METAC tRNA pseudouridine synthase A - Methanosarcina acetivorans| Length = 269 Score = 56.2 bits (134), Expect = 5e-07 Identities = 40/134 (29%), Positives = 65/134 (48%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 RV L++ Y+G+E+ G Q Q ++ T+E L A+ I+ES + + + R Sbjct: 2 RVALKLAYIGTEFHGSQIQPNVE---TVEKELFKALRNLS-IIESP----KSADYTCAGR 53 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH+L +++ E P+ +A+ INS LP I ++ FD RR Sbjct: 54 TDAGVHALGQVVAFDTEKPN---------LAIPRVINSELPPAIWAWAHAEVPYYFDARR 104 Query: 653 ECLYREYFYLLPAE 694 + R Y Y++ E Sbjct: 105 SAVSRHYHYVMSGE 118
>Q9JXI2:TRUA_NEIMB tRNA pseudouridine synthase A - Neisseria meningitidis serogroup B| Length = 265 Score = 54.3 bits (129), Expect = 2e-06 Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 2/139 (1%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 ++ +K+R + + Y GS + G QKQ D G T+++ LE+A+ + G + V Sbjct: 2 DTAQKQRWAITLSYDGSRFYGWQKQAD--GVPTVQAALETALAQIAG---------EAVS 50 Query: 455 WERSSRTDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPA 628 + RTD GVH+ A ++ P +AW + +N++LP+ I V Sbjct: 51 TTVAGRTDTGVHATAQVVHFDTTAARPQQAWVRG---------VNAHLPEGIAVLHARQV 101 Query: 629 QRSFDVRRECLYREYFYLL 685 F R + R Y YLL Sbjct: 102 APEFHARFDAYGRHYRYLL 120
>Q9JWF1:TRUA_NEIMA tRNA pseudouridine synthase A - Neisseria meningitidis serogroup A| Length = 265 Score = 54.3 bits (129), Expect = 2e-06 Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 2/139 (1%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 ++ +K+R + + Y GS + G QKQ D G T+++ LE+A+ + G + V Sbjct: 2 DTAQKQRWAITLSYDGSRFYGWQKQAD--GVPTVQAALETALAQIAG---------EAVS 50 Query: 455 WERSSRTDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPA 628 + RTD GVH+ A ++ P +AW + +N++LP+ I V Sbjct: 51 TTVAGRTDTGVHATAQVVHFDTTAARPQQAWVRG---------VNAHLPEGIAVLHARQV 101 Query: 629 QRSFDVRRECLYREYFYLL 685 F R + R Y YLL Sbjct: 102 APEFHARFDAYGRHYRYLL 120
>Q5F5V8:TRUA_NEIG1 tRNA pseudouridine synthase A - Neisseria gonorrhoeae (strain ATCC| 700825 / FA 1090) Length = 265 Score = 51.2 bits (121), Expect = 1e-05 Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 2/139 (1%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 ++ +K+R + + Y GS + G QKQ G T+++ LE+A+ + G + V Sbjct: 2 DTAQKQRWAITLSYDGSRFYGWQKQA--GGVPTVQAALETALARIAG---------ESVA 50 Query: 455 WERSSRTDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPA 628 + RTD GVH+ A ++ P +AW + +N++LP+ I V Sbjct: 51 TTVAGRTDTGVHATAQVVHFDTAAVRPAQAWIRG---------VNAHLPEGIAVLHARQV 101 Query: 629 QRSFDVRRECLYREYFYLL 685 F R + R Y YLL Sbjct: 102 APGFHARFDASGRHYRYLL 120
>Q8R7Y7:TRUA_THETN tRNA pseudouridine synthase A - Thermoanaerobacter tengcongensis| Length = 240 Score = 50.8 bits (120), Expect = 2e-05 Identities = 40/129 (31%), Positives = 62/129 (48%) Frame = +2 Query: 299 VLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTD 478 +L + Y G+ Y G Q Q++ T++ VLE AI K G +KV SSRTD Sbjct: 1 MLIIEYDGTNYHGWQYQKNAI---TVQEVLEKAIEKVTG---------EKVNLIGSSRTD 48 Query: 479 KGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRREC 658 GVH+L + + K + + P+ + A +N+ LPD++ V +SF R Sbjct: 49 TGVHALYQVANFKTKT-----KIPPEKLPYA--LNAVLPDDVVVVKAKEVDKSFHARYSA 101 Query: 659 LYREYFYLL 685 + Y YL+ Sbjct: 102 RSKRYRYLI 110
>Q890R5:TRUA2_CLOTE tRNA pseudouridine synthase A 2 - Clostridium tetani| Length = 248 Score = 50.4 bits (119), Expect = 3e-05 Identities = 42/132 (31%), Positives = 63/132 (47%), Gaps = 2/132 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 + V L+V Y G+ Y G QKQ+D TI+S +E A I E+ +++ +G SS Sbjct: 3 RNVRLKVEYDGTNYSGWQKQKD-KNIKTIQSSIEKA------IEEATKEEVELIG---SS 52 Query: 470 RTDKGVHSLATMISLK--MEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH+LA + K IP G + +N LP++I + F Sbjct: 53 RTDAGVHALAYTANFKTCSTIP---------GEKFKHALNRFLPEDIVILESEEVPMEFH 103 Query: 644 VRRECLYREYFY 679 R +C+ + Y Y Sbjct: 104 SRFDCIGKTYVY 115
>Q9PJT0:TRUA_CHLMU tRNA pseudouridine synthase A - Chlamydia muridarum| Length = 267 Score = 50.1 bits (118), Expect = 3e-05 Identities = 45/174 (25%), Positives = 72/174 (41%), Gaps = 3/174 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 K+++LR+ Y G+ Y G Q Q + +I+ VLE+ + K ++ S Sbjct: 3 KKIILRIAYQGTAYSGWQYQPNA---LSIQEVLETLLQKI---------SRTRISVIASG 50 Query: 470 RTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVR 649 RTD GVH+ + PD DP I +N+ LP +I + ++ F R Sbjct: 51 RTDAGVHAQGQVAHFC--CPDHPHFSDPGQI--KKMLNALLPHDIVIRDVIATNEDFHSR 106 Query: 650 RECLYREYFY---LLPAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNY 802 + +EY Y LLP + + C S + L K G H F ++ Sbjct: 107 FSAITKEYHYTLSLLPKPLPHHRLFCFSPRHKLCLESMREAAKYLVGTHDFASF 160
>Q9X1R0:TRUA_THEMA tRNA pseudouridine synthase A - Thermotoga maritima| Length = 245 Score = 49.3 bits (116), Expect = 6e-05 Identities = 49/192 (25%), Positives = 82/192 (42%), Gaps = 6/192 (3%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESA---IFKAGGILESNYGKLQKVGWE 460 KRV + Y GS + G Q Q D+ T++ V+E A IFK Q++ + Sbjct: 2 KRVAAVIEYDGSNFFGYQGQPDVR---TVQGVIEDALERIFK------------QRIYTQ 46 Query: 461 RSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSF 640 + RTD GVH+ +I+ DR +D + N +N+NLPD++ V + +F Sbjct: 47 AAGRTDTGVHANGQLIAFNCP-NDRMTTED-----IRNAMNANLPDDVYVKEVFEVPVNF 100 Query: 641 DVRRECLYREYFYLL---PAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNYTAR 811 R + R Y Y + + + ++ E L +K EG H F ++ Sbjct: 101 HPRFDVTKRIYHYFILTSRQKNVFLRKYVWWFPYELDLDAMRKAVKYLEGTHDFTSFKTG 160 Query: 812 AKYRKVLAGAHR 847 + R + +R Sbjct: 161 SDERDPVRTIYR 172
>Q8CXQ1:TRUA_MYCPE tRNA pseudouridine synthase A - Mycoplasma penetrans| Length = 241 Score = 49.3 bits (116), Expect = 6e-05 Identities = 41/128 (32%), Positives = 59/128 (46%) Frame = +2 Query: 302 LRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDK 481 L++ Y GS +RG KQ+D T++S LE + S +G S RTDK Sbjct: 5 LKISYDGSFFRGYAKQKD-ENLITVQSELEKYLSLFFNTKISTFG---------SGRTDK 54 Query: 482 GVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECL 661 VH++ +S K + D D ++ NF+NS L NI V SI SF R Sbjct: 55 YVHAIDQTVSFKC-------DSDYDPKSIQNFLNSKL-TNIYVNSIEKVPNSFHARFSIK 106 Query: 662 YREYFYLL 685 + Y Y++ Sbjct: 107 SKTYMYVI 114
>Q5NG36:TRUA_FRATT tRNA pseudouridine synthase A - Francisella tularensis subsp.| tularensis Length = 258 Score = 48.5 bits (114), Expect = 1e-04 Identities = 40/161 (24%), Positives = 71/161 (44%), Gaps = 2/161 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 K +L++ Y G Y G Q+Q S +++ LE A+ K Q + + Sbjct: 2 KNYLLQIEYFGKNYCGWQRQ---SHSPSVQEELEKALSKIAN---------QNIEVTCAG 49 Query: 470 RTDKGVHSLATMISL--KMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH+ + +++ + P AW++ +N+ LP +IK+ ++ +F+ Sbjct: 50 RTDTGVHATSQIVNFYSNADRPLSAWQRG---------VNALLPQDIKILAVQQVDNNFN 100 Query: 644 VRRECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNIL 766 R + R Y Y++ S+ SS EH + N L Sbjct: 101 SRFTAINRTYNYII------YNSATSSPIFAEHCLWENREL 135
>Q7TU31:TRUA_PROMP tRNA pseudouridine synthase A - Prochlorococcus marinus subsp.| pastoris (strain CCMP 1378 / MED4) Length = 268 Score = 47.8 bits (112), Expect = 2e-04 Identities = 36/135 (26%), Positives = 63/135 (46%), Gaps = 3/135 (2%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 KRV L + Y GS + G Q+Q++ +++ +E+ +FK + + S Sbjct: 2 KRVALVIQYDGSYFSGWQRQKNAI---SVQETIENCLFKISNQIIKTFA---------SG 49 Query: 470 RTDKGVHSLATMISLKME--IP-DRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSF 640 RTD GVH+ +I ++ IP DR A+ +NS LP I++ + + S+ Sbjct: 50 RTDAGVHASGQVIHFDIDFLIPIDR----------YADVLNSRLPHTIRILESVEVKSSW 99 Query: 641 DVRRECLYREYFYLL 685 +YR Y Y++ Sbjct: 100 HACYSAVYRHYRYVI 114
>Q8K9U4:TRUA_BUCAP tRNA pseudouridine synthase A - Buchnera aphidicola subsp.| Schizaphis graminum Length = 263 Score = 47.8 bits (112), Expect = 2e-04 Identities = 41/134 (30%), Positives = 59/134 (44%) Frame = +2 Query: 284 RKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWER 463 + K+ L V Y GS Y G Q Q+ LS TI+S +E A+ K +V Sbjct: 5 KNKKFALGVEYDGSYYHGWQSQKGLS---TIQSEIEKALSKIAN---------HQVNVIC 52 Query: 464 SSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 + RTD GVHS+ +I ++ D I +NS L NI V I +F+ Sbjct: 53 AGRTDSGVHSIGQVI----HFTSISFRSDFSWIV---GVNSYLSKNISVKWIKEVSENFN 105 Query: 644 VRRECLYREYFYLL 685 R + R Y Y++ Sbjct: 106 ARYSAISRSYRYII 119
>P73295:TRUA_SYNY3 tRNA pseudouridine synthase A - Synechocystis sp. (strain PCC 6803)| Length = 275 Score = 47.4 bits (111), Expect = 2e-04 Identities = 40/137 (29%), Positives = 59/137 (43%), Gaps = 3/137 (2%) Frame = +2 Query: 278 STRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGW 457 S K+RV L + Y+G+ + G Q+Q + S+I+ +E AI K G Q V Sbjct: 6 SAGKQRVALVMQYLGTHFHGWQRQPNF---SSIQEEVELAIAKVVG---------QPVTL 53 Query: 458 ERSSRTDKGVHSLATMISLK---MEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPA 628 + RTD GVH+ A + +IP W K +N +LP +I V Sbjct: 54 HGAGRTDAGVHAAAQVAHFDDPVGQIPPHRWSK---------ILNGHLPQDIIVRGSAAV 104 Query: 629 QRSFDVRRECLYREYFY 679 + R L+R Y Y Sbjct: 105 DSHWHARFSALWRRYRY 121
>Q7V9Y7:TRUA_PROMA tRNA pseudouridine synthase A - Prochlorococcus marinus| Length = 289 Score = 47.4 bits (111), Expect = 2e-04 Identities = 39/139 (28%), Positives = 65/139 (46%), Gaps = 2/139 (1%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 + ++ KR+ L + Y GS + G Q+Q+ TI+++LE AIF L+S+ K KV Sbjct: 11 KESKIKRIALSIQYQGSNFSGWQRQK---VGHTIQAILEDAIFS----LDSS--KPAKV- 60 Query: 455 WERSSRTDKGVHSLATMISLKM--EIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPA 628 + RTD GVH+ ++ IP W + +N LP+ I+V + Sbjct: 61 -VAAGRTDAGVHAAGQVVHFDSFGPIPVHRW---------PSALNGRLPEAIRVRDSVEQ 110 Query: 629 QRSFDVRRECLYREYFYLL 685 + +YR Y Y++ Sbjct: 111 SLDWHACHSAVYRRYRYII 129
>Q8D2P5:TRUA_WIGBR tRNA pseudouridine synthase A - Wigglesworthia glossinidia| brevipalpis Length = 264 Score = 47.0 bits (110), Expect = 3e-04 Identities = 40/174 (22%), Positives = 80/174 (45%), Gaps = 3/174 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 K++ + Y G+ Y G Q Q+++ +I+ +E A+FK G +K+ + Sbjct: 2 KKLAAGISYQGNNYCGWQSQKNII---SIQEYVELALFKFSG---------EKIKIYCAG 49 Query: 470 RTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVR 649 RTD VH+L ++ +I R++ + G+ NS LP +I + ++ +F R Sbjct: 50 RTDAKVHALLQVVHFYTDIK-RSYRQWILGV------NSYLPYDISIMWVIKVHNNFHAR 102 Query: 650 RECLYREYFYLLPAEI--IGI-KSSCSSGEVEEHLIEFNNILKGFEGNHPFHNY 802 + ++Y YL+ I GI + C + + ++ + + G H F ++ Sbjct: 103 YSAIAKKYLYLIHNNISRSGIFRKYCFNVFISLNINDMKKAAQKLIGKHDFSSF 156
>Q8FS31:TRUA_COREF tRNA pseudouridine synthase A - Corynebacterium efficiens| Length = 282 Score = 47.0 bits (110), Expect = 3e-04 Identities = 39/142 (27%), Positives = 65/142 (45%), Gaps = 5/142 (3%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERS-- 466 R+ L + Y G+++ G +Q GDS + +V + +LE N G + + E + Sbjct: 2 RIRLDLDYDGTDFHGWARQ----GDSDLRTVQK--------VLEDNLGMVLRAPVELTVA 49 Query: 467 SRTDKGVHSLATMISLKMEIPDRAWEK---DPDGIALANFINSNLPDNIKVFSILPAQRS 637 RTD GVH+ + +IP + ++ D D L ++ LP++I+V + A Sbjct: 50 GRTDAGVHAAGQVAHF--DIPRESLQQRSIDGDPTKLVRRLSRLLPEDIRVHGVNYAPEG 107 Query: 638 FDVRRECLYREYFYLLPAEIIG 703 FD R L R Y Y + G Sbjct: 108 FDARFSALRRHYVYRITTHPAG 129
>Q6G547:TRUA_BARHE tRNA pseudouridine synthase A - Bartonella henselae (Rochalimaea| henselae) Length = 247 Score = 47.0 bits (110), Expect = 3e-04 Identities = 38/132 (28%), Positives = 59/132 (44%), Gaps = 3/132 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R L + Y GS Y G Q+Q +L TI+S LE A+F G Q++ + R Sbjct: 3 RFKLTLEYDGSNYAGWQRQAELR---TIQSALEQALFHFSG---------QQLTITTAGR 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLP---DNIKVFSILPAQRSFD 643 TD GVH+ + + E + W + + +N++L DNI + + SFD Sbjct: 51 TDAGVHATGQVAHVDFE---KNWRTH----TVRDALNAHLQKQGDNIAILHVQNVPDSFD 103 Query: 644 VRRECLYREYFY 679 R + R Y + Sbjct: 104 ARFSAIKRHYLF 115
>Q7TU07:TRUA_RHOBA tRNA pseudouridine synthase A - Rhodopirellula baltica| Length = 276 Score = 46.2 bits (108), Expect = 5e-04 Identities = 39/134 (29%), Positives = 62/134 (46%) Frame = +2 Query: 284 RKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWER 463 R + L V Y G+EY G Q Q + +I+S LE I G + V Sbjct: 6 RPRTFHLTVAYDGTEYCGWQVQPE---QRSIQSELERVIRPLAG---------RPVRVLG 53 Query: 464 SSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 S RTD GVH++ + + + W+ D +AL INS LP++I+V ++ + F Sbjct: 54 SGRTDAGVHAIGQVARCVLPV----WKADT--VALQRAINSKLPNDIRVKAVRETRERFH 107 Query: 644 VRRECLYREYFYLL 685 + ++Y YL+ Sbjct: 108 PIADATGKQYQYLV 121
>Q6F1W2:TRUA_MESFL tRNA pseudouridine synthase A - Mesoplasma florum (Acholeplasma| florum) Length = 251 Score = 45.8 bits (107), Expect = 6e-04 Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 8/175 (4%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSG-----DSTIESVLESAIFKAGGILESNYGKLQKVGW 457 + ++ + Y GS++ G +Q S + I V ++A+FK G Sbjct: 3 KFLITLEYDGSDFHGWIEQPKTSTIQGELNKAINRVTKNAVFKTIG-------------- 48 Query: 458 ERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRS 637 +S+TD GVH++ + L + +P IN LP+ IKV SI ++ Sbjct: 49 --ASKTDTGVHAIDQKVLLDLGF-------NPKLDLFKKAINKALPETIKVRSIEEVKQD 99 Query: 638 FDVRRECLYREYFYLLPAEIIGIKSSC--SSGEVEE-HLIEFNNILKGFEGNHPF 793 F++ R+ LY+EY Y + + I S+ + + EE + + NI F G H F Sbjct: 100 FNI-RDVLYKEYSYTINDKEYNILSNRFELNWDFEEIDIDKLQNIFNLFIGEHEF 153
>Q5QUE5:TRUA_IDILO tRNA pseudouridine synthase A - Idiomarina loihiensis| Length = 261 Score = 45.8 bits (107), Expect = 6e-04 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L + Y GS Y G Q+QR+++ +++ +E A+ K V + R Sbjct: 2 RMALCLEYDGSRYYGWQRQREVA---SVQQCVEEALSKIANA---------PVEVTCAGR 49 Query: 473 TDKGVHSLATMISLKMEIP--DRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH+ A ++ + +P D AW +NSNLP I V F Sbjct: 50 TDAGVHATAQIVHFDVPVPRADVAWTLG---------VNSNLPAGIAVRWAREVDSEFSA 100 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 101 RFSATSRRYRYII 113
>Q8NSV0:TRUA_CORGL tRNA pseudouridine synthase A - Corynebacterium glutamicum| (Brevibacterium flavum) Length = 289 Score = 45.8 bits (107), Expect = 6e-04 Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 5/142 (3%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKL--QKVGWERS 466 R+ L + Y G+++ G KQ G S + +V + +LE N + + V + Sbjct: 2 RIRLDLAYDGTDFHGWAKQ----GTSDLRTVQK--------VLEDNLSMVLRETVELTVA 49 Query: 467 SRTDKGVHSLATMISLKMEIPDRAWEK---DPDGIALANFINSNLPDNIKVFSILPAQRS 637 RTD GVH+ + +IP A E+ D D L + LPD+I+V + A+ Sbjct: 50 GRTDAGVHAAGQVAHF--DIPAHALEQRSIDGDPSKLVRRLGRLLPDDIRVHGVRFAEPG 107 Query: 638 FDVRRECLYREYFYLLPAEIIG 703 FD R + R Y Y + G Sbjct: 108 FDARFSAMRRHYVYRITTHPAG 129
>Q8YPK5:TRUA_ANASP tRNA pseudouridine synthase A - Anabaena sp. (strain PCC 7120)| Length = 282 Score = 45.8 bits (107), Expect = 6e-04 Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 2/137 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 +RV L V Y+G+ + G Q+Q+ T++ +E+AI K G + +G + Sbjct: 11 QRVALVVQYLGTHFHGWQRQKQ---HRTVQEEIETAIAKILGHHVTLHG---------AG 58 Query: 470 RTDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH+ A + IP W A+ INS LP +I + + + Sbjct: 59 RTDSGVHAAAQVAHFDATGLIPAHKW---------ASVINSYLPKDILIKASAAVGDRWH 109 Query: 644 VRRECLYREYFYLLPAE 694 R YR Y Y + E Sbjct: 110 ARFSAAYRRYRYTIYTE 126
>Q72DL8:TRUA_DESVH tRNA pseudouridine synthase A - Desulfovibrio vulgaris (strain| Hildenborough / ATCC 29579 / NCIMB 8303) Length = 297 Score = 45.1 bits (105), Expect = 0.001 Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDS--TIESVLESAIFKAGGILESNYGKLQKVGWERS 466 R+ L + Y G++ G Q Q + T++ VLE + + G ++V + Sbjct: 3 RLRLTIAYKGTDLHGWQVQEHATRPRPRTVQGVLEPIVSRMAG---------EQVRLHAA 53 Query: 467 SRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 RTD GVH+ + + +IPD G+ IN+ LPD+I + + A F Sbjct: 54 GRTDAGVHADGQVAHV--DIPDHKL-----GVDWQKAINAQLPDDICILDVRRAADDFHA 106 Query: 647 RRECLYREYFYLL 685 R + L + Y Y L Sbjct: 107 RFDALGKRYTYRL 119
>Q7U356:TRUA_BLOFL tRNA pseudouridine synthase A - Blochmannia floridanus| Length = 252 Score = 45.1 bits (105), Expect = 0.001 Identities = 41/134 (30%), Positives = 63/134 (47%), Gaps = 2/134 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 +++VL V Y GS Y G QKQ+ +S +I+S LE A+ K S+ L G Sbjct: 2 QKLVLGVEYDGSMYCGWQKQKCVS---SIQSCLEYALSKV-----SSESILVFCG----G 49 Query: 470 RTDKGVHSLATMISLKMEIP--DRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH+L ++ + ++ AW +N +LP++I V + SF Sbjct: 50 RTDSGVHALEQIVHFETQLKCSRSAWTLG---------VNCHLPNDICVRWVSEVDNSFH 100 Query: 644 VRRECLYREYFYLL 685 R + R Y Y + Sbjct: 101 ARFSAISRRYCYFI 114
>Q6AKP0:TRUA2_DESPS tRNA pseudouridine synthase A 2 - Desulfotalea psychrophila| Length = 261 Score = 45.1 bits (105), Expect = 0.001 Identities = 41/180 (22%), Positives = 85/180 (47%), Gaps = 10/180 (5%) Frame = +2 Query: 302 LRVGYVGSEYRGLQKQR-DLSGDS--TIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 +++ Y G+ Y G Q Q D + T+E + +A+ K +NY G +SR Sbjct: 6 VKIAYKGTHYFGWQAQSIDTLHEEKPTVEGTILNALKKI-----TNYQPCTVSG---ASR 57 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH+ + + + + + P+ + L +NS LP +I++ +P+ + + R Sbjct: 58 TDGGVHARGQIAKITI-----SQKISPEHLLLG--LNSLLPTDIRILECVPSTKEYQASR 110 Query: 653 ECLYREY-FYLLPAEIIGIKSSCSSGEV------EEHLIEFNNILKGFEGNHPFHNYTAR 811 + +EY +Y + + + + +S + + + L + + F G H F+N+++R Sbjct: 111 GSVSKEYHYYFIASPVDNVATSDIALHLPIDSIGPDDLALLRSACRLFVGRHDFYNFSSR 170
>Q5SHU9:TRUA_THET8 tRNA pseudouridine synthase A - Thermus thermophilus (strain HB8 /| ATCC 27634 / DSM 579) Length = 253 Score = 44.7 bits (104), Expect = 0.001 Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 2/132 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 +R++L Y G+ + GLQ+Q G T++ LE A+ G + ++ + Sbjct: 2 RRLLLLCEYDGTLFAGLQRQG--RGLRTVQGELERALPGIGALPKA----------VAAG 49 Query: 470 RTDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH+LA + +E IP EK P+ +N LP+++KV F Sbjct: 50 RTDAGVHALAMPFHVDVESAIP---VEKVPEA------LNRLLPEDLKVVGAREVAPDFH 100 Query: 644 VRRECLYREYFY 679 R++ L+R Y Y Sbjct: 101 ARKDALWRAYRY 112 Score = 32.3 bits (72), Expect = 7.1 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Frame = +2 Query: 1082 RDILTCSCGELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAK 1261 R++L + +G++ V L G SF+ Q+R MVGT + V G P + +K L Sbjct: 166 RELLEARLQVAEGEAGLE-VRLYFRGKSFLRGQVRGMVGTLLEVGLGKRPPESLKAILKT 224 Query: 1262 FS-RIVLPIAPSEVL 1303 R+ P AP+ L Sbjct: 225 ADRRLAGPTAPAHGL 239
>Q72I65:TRUA_THET2 tRNA pseudouridine synthase A - Thermus thermophilus (strain HB27 /| ATCC BAA-163 / DSM 7039) Length = 253 Score = 44.7 bits (104), Expect = 0.001 Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 2/132 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 +R++L Y G+ + GLQ+Q G T++ LE A+ G + ++ + Sbjct: 2 RRLLLLCEYDGTLFAGLQRQG--RGLRTVQGELERALPGIGALPKA----------VAAG 49 Query: 470 RTDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH+LA + +E IP EK P+ +N LP+++KV F Sbjct: 50 RTDAGVHALAMPFHVDVESAIP---VEKVPEA------LNRLLPEDLKVVGAREVAPDFH 100 Query: 644 VRRECLYREYFY 679 R++ L+R Y Y Sbjct: 101 ARKDALWRAYRY 112 Score = 32.3 bits (72), Expect = 7.1 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Frame = +2 Query: 1082 RDILTCSCGELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAK 1261 R++L + +G++ V L G SF+ Q+R MVGT + V G P + +K L Sbjct: 166 RELLEARLQVAEGEAGLE-VRLYFRGKSFLRGQVRGMVGTLLEVGLGKRPPESLKAILKT 224 Query: 1262 FS-RIVLPIAPSEVL 1303 R+ P AP+ L Sbjct: 225 ADRRLAGPTAPAHGL 239
>O87016:TRUA_PSEAE tRNA pseudouridine synthase A - Pseudomonas aeruginosa| Length = 285 Score = 44.7 bits (104), Expect = 0.001 Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 4/135 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L + Y GS YRG Q+Q +G +++ LE A+ K + VG + R Sbjct: 19 RIALGIEYKGSRYRGWQRQE--AGVPSVQEALERALSKVAA---------EPVGVICAGR 67 Query: 473 TDKGVHSLATMI--SLKMEIPDRAWEKDPDGIALANFINSNLPDNIKV--FSILPAQRSF 640 TD VH+ ++ +E P +AW N+NLP +I V ++PA F Sbjct: 68 TDAAVHASGQVVHFDTAVERPLKAWVMG---------TNANLPADISVTWARVMPAH--F 116 Query: 641 DVRRECLYREYFYLL 685 R + R Y Y + Sbjct: 117 HARFSAMARRYRYAI 131
>Q668W9:TRUA_YERPS tRNA pseudouridine synthase A - Yersinia pseudotuberculosis| Length = 264 Score = 44.3 bits (103), Expect = 0.002 Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y GS Y G Q+Q++++ ++++ LE+A+ K + +G + R Sbjct: 2 KIALGIEYNGSRYFGWQRQQEVA---SVQACLEAALSKVAN---------EPIGVFCAGR 49 Query: 473 TDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH+ ++ D AW +NS+LP +I V + F Sbjct: 50 TDAGVHATGQVVHFVTSAVRKDAAWTMG---------VNSHLPADIAVRWVKTVDNDFHA 100 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 101 RFSATARRYRYII 113
>Q8ZD27:TRUA_YERPE tRNA pseudouridine synthase A - Yersinia pestis| Length = 264 Score = 44.3 bits (103), Expect = 0.002 Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y GS Y G Q+Q++++ ++++ LE+A+ K + +G + R Sbjct: 2 KIALGIEYNGSRYFGWQRQQEVA---SVQACLEAALSKVAN---------EPIGVFCAGR 49 Query: 473 TDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH+ ++ D AW +NS+LP +I V + F Sbjct: 50 TDAGVHATGQVVHFVTSAVRKDAAWTMG---------VNSHLPADIAVRWVKTVDNDFHA 100 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 101 RFSATARRYRYII 113
>Q5UXW0:TRUA_HALMA tRNA pseudouridine synthase A - Haloarcula marismortui| (Halobacterium marismortui) Length = 275 Score = 44.3 bits (103), Expect = 0.002 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 3/170 (1%) Frame = +2 Query: 305 RVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDKG 484 RV Y G Y G Q+Q D+ T+E L SA+ + G+ E G + + + RTD G Sbjct: 5 RVAYDGQPYHGFQRQPDV---DTVEGRLRSALVRL-GVCERGEGLPDR--YAAAGRTDAG 58 Query: 485 VHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECLY 664 V + ++ P ++ A F N LP++++V++ F + Sbjct: 59 VSARTQTVAFDA----------PAWLSPAAF-NGELPNDVRVWASADVPEDFHATHDAAE 107 Query: 665 REYFYLLPAEIIGIKSSCSSGEVEEHLIE---FNNILKGFEGNHPFHNYT 805 R Y Y L A + E ++ + + + G H FHN T Sbjct: 108 RTYTYYLYA-------PADADRPEHEPVDDGRWADAVDALAGTHDFHNLT 150
>O66953:TRUA_AQUAE tRNA pseudouridine synthase A - Aquifex aeolicus| Length = 241 Score = 44.3 bits (103), Expect = 0.002 Identities = 44/181 (24%), Positives = 77/181 (42%), Gaps = 3/181 (1%) Frame = +2 Query: 299 VLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTD 478 +LR+ +VG+ + G Q Q +L T++ ++ A+ + + V RTD Sbjct: 5 LLRLAFVGTNFYGWQVQPNLR---TVQGEIQKALSQI---------LCEDVKVTGCCRTD 52 Query: 479 KGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRREC 658 GVH+L + + K + KD L +N LP ++ V+++ F+ R Sbjct: 53 SGVHALDYIANFKTQ-------KDFPEEKLLKALNGILPKDVGVYAVKKVSEEFNARYSV 105 Query: 659 LYREYFYLL-PAEIIGIKSSCSSGEVEEHLIE--FNNILKGFEGNHPFHNYTARAKYRKV 829 + Y Y + +E+ S +V+ + NILK FEG H F T + R Sbjct: 106 KGKVYLYKIWNSEVRNPFLYPFSWQVKREINTEVLRNILKKFEGTHDFRALTKLEEERNT 165 Query: 830 L 832 + Sbjct: 166 V 166
>Q6D2N7:TRUA_ERWCT tRNA pseudouridine synthase A - Erwinia carotovora subsp.| atroseptica (Pectobacterium atrosepticum) Length = 283 Score = 43.5 bits (101), Expect = 0.003 Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y GS+Y G Q+Q D++ ++++ LE A+ K + + + R Sbjct: 24 KIALGIEYDGSQYYGWQRQIDVA---SVQACLEKALSKVAD---------EPIEVLCAGR 71 Query: 473 TDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH ++ + D AW +N+NLP +I V + F Sbjct: 72 TDAGVHGTGQVVHFTTQAIRKDAAWTMG---------VNANLPPDIAVRWVKAVHEDFHA 122 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 123 RFSATARRYRYII 135
>Q7U328:TRUA_HELHP tRNA pseudouridine synthase A - Helicobacter hepaticus| Length = 248 Score = 43.1 bits (100), Expect = 0.004 Identities = 46/175 (26%), Positives = 70/175 (40%), Gaps = 2/175 (1%) Frame = +2 Query: 308 VGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDKGV 487 + Y GS + G Q+D S + ++ E F GI G + RTDKGV Sbjct: 8 IAYDGSVFSGFALQKDKRLKSVLGTLKEG--FARVGIKSDIIG---------AGRTDKGV 56 Query: 488 HSLATMISLKMEIPDRAWEKDPDGIALANFI-NSNLPDNIKVFSILPAQRSFDVRRECLY 664 H+ +I + + I F+ N+ L +I V S+ +F R + L+ Sbjct: 57 HATGQVICFQSA---HFLDSQVQAIESLRFLLNAKLYPHIMVRSLHIVDDTFHPRFDALW 113 Query: 665 REYFYLL-PAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNYTARAKYRK 826 R Y +LL P + + S E F N L+ F+G H F + Y K Sbjct: 114 RSYRFLLSPTQPSPFAAPYVSYEKIGDETLFKNALQAFQGQHNFVFFKKNGSYTK 168
>Q5L3Q7:TRUA_GEOKA tRNA pseudouridine synthase A - Geobacillus kaustophilus| Length = 258 Score = 43.1 bits (100), Expect = 0.004 Identities = 41/176 (23%), Positives = 68/176 (38%), Gaps = 5/176 (2%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 +R+ + Y G+ + G Q Q G T++ E + + K KV S Sbjct: 3 QRIKCIIAYDGTHFSGYQIQ---PGKRTVQGEFEEVLRRMH--------KGTKVRVAASG 51 Query: 470 RTDKGVHSLATMISLK--MEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH+ +I + + W+K +N+ LPD+I V + A F Sbjct: 52 RTDAGVHAYGQVIHFDTPLSLSSEQWKKA---------LNAQLPDDIVVRFVQEADADFH 102 Query: 644 VRRECLYREYFYLL---PAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNY 802 R +EY Y + + + C+ H+ N L+ G H F ++ Sbjct: 103 ARFSAKAKEYRYKVWTAAERDVFRRHYCAWHPYSLHISAMNEALRLLHGTHDFTSF 158 Score = 34.7 bits (78), Expect = 1.4 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Frame = +2 Query: 1139 VELTICGVSFMLHQIRKMVGTAVAVKRGLL-PKDIIKLSLAKFSRIVLPIAPSEVLIL 1309 +E G F+ + +R +VGT + + +G P DI L AK R+ P AP+E L L Sbjct: 184 LEFRFVGSGFLYNMVRIIVGTVLEIGQGKRSPADISTLLAAKDRRLAGPTAPAEGLYL 241
>Q7M7J4:TRUA_VIBVY tRNA pseudouridine synthase A - Vibrio vulnificus (strain YJ016)| Length = 264 Score = 42.7 bits (99), Expect = 0.005 Identities = 39/154 (25%), Positives = 64/154 (41%), Gaps = 5/154 (3%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L + Y G++Y G Q+QR+++ +++ LE A+ K V + + R Sbjct: 2 RIALGIEYNGTDYFGWQRQREVA---SVQEKLEKALSKVAN---------HPVEVQCAGR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH ++ + + +A N+NLP +I V F R Sbjct: 50 TDAGVHGTGQVVHFDTNVERKM-------VAWTMGANANLPKDIAVRWAKAVPDEFHARF 102 Query: 653 ECLYREYFYL-----LPAEIIGIKSSCSSGEVEE 739 R Y Y+ L I+G S GE++E Sbjct: 103 SATARRYRYIIFNHALRPGILGSGVSHYHGELDE 136
>Q8CWK3:TRUA_VIBVU tRNA pseudouridine synthase A - Vibrio vulnificus| Length = 264 Score = 42.7 bits (99), Expect = 0.005 Identities = 39/154 (25%), Positives = 64/154 (41%), Gaps = 5/154 (3%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L + Y G++Y G Q+QR+++ +++ LE A+ K V + + R Sbjct: 2 RIALGIEYNGTDYFGWQRQREVA---SVQEKLEKALSKVAN---------HPVEVQCAGR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH ++ + + +A N+NLP +I V F R Sbjct: 50 TDAGVHGTGQVVHFDTNVERKM-------VAWTMGANANLPKDIAVRWAKAVPDEFHARF 102 Query: 653 ECLYREYFYL-----LPAEIIGIKSSCSSGEVEE 739 R Y Y+ L I+G S GE++E Sbjct: 103 SATARRYRYIIFNHALRPGILGSGVSHYHGELDE 136
>Q820P8:TRUA_NITEU tRNA pseudouridine synthase A - Nitrosomonas europaea| Length = 272 Score = 42.7 bits (99), Expect = 0.005 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++VL + Y G Y G QKQ G +++S LESA+ G +++ + R Sbjct: 13 KIVLALEYDGRGYCGWQKQ---PGCLSVQSRLESALSGVAG---------RQIQVVAAGR 60 Query: 473 TDKGVHSLATMISLK--MEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH+L ++ L+ + P AW + N+ LP +I + F Sbjct: 61 TDAGVHALCQVVHLETCVRRPLNAWIRG---------TNALLPGDISILEASEVSDDFHA 111 Query: 647 RRECLYREYFYLL 685 R R Y Y L Sbjct: 112 RFSATERTYLYYL 124
>Q7TTT1:TRUA_SYNPX tRNA pseudouridine synthase A - Synechococcus sp. (strain WH8102)| Length = 299 Score = 42.4 bits (98), Expect = 0.007 Identities = 37/139 (26%), Positives = 61/139 (43%), Gaps = 2/139 (1%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 EST +R+ L + Y GS + G Q+QR+ +++++ LE+AI + Y +Q Sbjct: 11 ESTIPRRIALSLQYEGSAFCGWQRQRN---GNSVQAQLEAAIEQL-----DPYRPIQTFA 62 Query: 455 WERSSRTDKGVHSLATMISLKM--EIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPA 628 + RTD GVH+ ++ IP W A +N LP I+V + Sbjct: 63 ---AGRTDTGVHAAGQVVHFDCGDRIPPAKW---------APALNGRLPFTIRVRESVLR 110 Query: 629 QRSFDVRRECLYREYFYLL 685 + + YR Y Y + Sbjct: 111 PKDWHACYSATYRRYRYTI 129
>Q8NVB7:TRUA_STAAW tRNA pseudouridine synthase A - Staphylococcus aureus (strain MW2)| Length = 267 Score = 42.4 bits (98), Expect = 0.007 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 2/131 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+++ + Y G+ + G Q Q++ T++ E +L+ + + ++ SSR Sbjct: 2 RILVEIAYQGNNFLGFQIQQN---GRTVQQQFEK-------LLQRMHKRHVRI--HPSSR 49 Query: 473 TDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD+GVH++ E IP W+ +N LPD+I V +++ F Sbjct: 50 TDRGVHAIQQYFHFDTELNIPMSQWQYA---------MNRTLPDDIYVNNVVTVDDDFHC 100 Query: 647 RRECLYREYFY 679 R +C+ + Y Y Sbjct: 101 RYDCVGKRYRY 111
>Q6G7A2:TRUA_STAAS tRNA pseudouridine synthase A - Staphylococcus aureus (strain| MSSA476) Length = 267 Score = 42.4 bits (98), Expect = 0.007 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 2/131 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+++ + Y G+ + G Q Q++ T++ E +L+ + + ++ SSR Sbjct: 2 RILVEIAYQGNNFLGFQIQQN---GRTVQQQFEK-------LLQRMHKRHVRI--HPSSR 49 Query: 473 TDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD+GVH++ E IP W+ +N LPD+I V +++ F Sbjct: 50 TDRGVHAIQQYFHFDTELNIPMSQWQYA---------MNRTLPDDIYVNNVVTVDDDFHC 100 Query: 647 RRECLYREYFY 679 R +C+ + Y Y Sbjct: 101 RYDCVGKRYRY 111
>P65849:TRUA_STAAN tRNA pseudouridine synthase A - Staphylococcus aureus (strain N315)| Length = 267 Score = 42.4 bits (98), Expect = 0.007 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 2/131 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+++ + Y G+ + G Q Q++ T++ E +L+ + + ++ SSR Sbjct: 2 RILVEIAYQGNNFLGFQIQQN---GRTVQQQFEK-------LLQRMHKRHVRI--HPSSR 49 Query: 473 TDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD+GVH++ E IP W+ +N LPD+I V +++ F Sbjct: 50 TDRGVHAIQQYFHFDTELNIPMSQWQYA---------MNRTLPDDIYVNNVVTVDDDFHC 100 Query: 647 RRECLYREYFY 679 R +C+ + Y Y Sbjct: 101 RYDCVGKRYRY 111
>P65848:TRUA_STAAM tRNA pseudouridine synthase A - Staphylococcus aureus (strain Mu50| / ATCC 700699) Length = 267 Score = 42.4 bits (98), Expect = 0.007 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 2/131 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+++ + Y G+ + G Q Q++ T++ E +L+ + + ++ SSR Sbjct: 2 RILVEIAYQGNNFLGFQIQQN---GRTVQQQFEK-------LLQRMHKRHVRI--HPSSR 49 Query: 473 TDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD+GVH++ E IP W+ +N LPD+I V +++ F Sbjct: 50 TDRGVHAIQQYFHFDTELNIPMSQWQYA---------MNRTLPDDIYVNNVVTVDDDFHC 100 Query: 647 RRECLYREYFY 679 R +C+ + Y Y Sbjct: 101 RYDCVGKRYRY 111
>Q5HDY9:TRUA_STAAC tRNA pseudouridine synthase A - Staphylococcus aureus (strain COL)| Length = 267 Score = 42.4 bits (98), Expect = 0.007 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 2/131 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+++ + Y G+ + G Q Q++ T++ E +L+ + + ++ SSR Sbjct: 2 RILVEIAYQGNNFLGFQIQQN---GRTVQQQFEK-------LLQRMHKRHVRI--HPSSR 49 Query: 473 TDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD+GVH++ E IP W+ +N LPD+I V +++ F Sbjct: 50 TDRGVHAIQQYFHFDTELNIPMSQWQYA---------MNRTLPDDIYVNNVVTVDDDFHC 100 Query: 647 RRECLYREYFY 679 R +C+ + Y Y Sbjct: 101 RYDCVGKRYRY 111
>Q8R601:TRUA_FUSNN tRNA pseudouridine synthase A - Fusobacterium nucleatum subsp.| nucleatum Length = 247 Score = 42.4 bits (98), Expect = 0.007 Identities = 40/177 (22%), Positives = 71/177 (40%), Gaps = 4/177 (2%) Frame = +2 Query: 284 RKKRVVLRVGYVGSEYRGLQKQRD-LSGDSTIESVLESAIFKAGGILESNYGKLQKVGWE 460 R+K + + Y GS Y G Q+Q + ++ IE VL +++ Sbjct: 4 RRKNIKIEFRYDGSSYYGFQRQPNKITVQGEIEKVLRIVT-------------KEEINLI 50 Query: 461 RSSRTDKGVHSLATMISL--KMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQR 634 + RTD+GVH+ + + IP ++ + LP++I + S+ Sbjct: 51 SAGRTDRGVHANHQVSNFYTSSNIPIEKYKY---------LLTRALPNDIDILSVEEVDE 101 Query: 635 SFDVRRECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIE-FNNILKGFEGNHPFHNY 802 +F+ R REY Y++ E ++ E+ + E I F G H F N+ Sbjct: 102 NFNARHNAKMREYIYIISWEKNPFEARYCKFVKEKIVAEKLEKIFSDFIGVHDFKNF 158 Score = 32.3 bits (72), Expect = 7.1 Identities = 17/48 (35%), Positives = 30/48 (62%) Frame = +2 Query: 1127 GVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSR 1270 G +++ I G +F+ Q+R MVGTA+ + G L ++ I+L L F++ Sbjct: 181 GENKIKIYIKGSAFLKSQVRIMVGTALEIYYGRLLENHIRLMLNDFTK 228
>P70830:TRUA_BORBU tRNA pseudouridine synthase A - Borrelia burgdorferi (Lyme disease| spirochete) Length = 246 Score = 42.4 bits (98), Expect = 0.007 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 2/134 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 K+++ + Y GS Y G Q Q T++ +E A+ K +KV S Sbjct: 2 KKILAEIAYDGSIYHGFQIQPT---KPTVQGEIEKALMKINK---------KKVKIHSSG 49 Query: 470 RTDKGVHSLATMIS--LKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTDKGVH+ +I+ +K+ I +K + I L N +IK+ + + SF Sbjct: 50 RTDKGVHAKKQIITFDIKINIQLNNLKKALNAILLKN--------SIKILKLRYVKNSFH 101 Query: 644 VRRECLYREYFYLL 685 R R+Y Y + Sbjct: 102 PRFSAQKRKYSYCI 115
>Q6G1G9:TRUA_BARQU tRNA pseudouridine synthase A - Bartonella quintana (Rochalimaea| quintana) Length = 247 Score = 42.4 bits (98), Expect = 0.007 Identities = 36/129 (27%), Positives = 56/129 (43%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R L + Y GS Y G Q+Q +L TI+S LE AIF G Q++ + R Sbjct: 3 RFKLTLEYDGSNYAGWQRQAEL---HTIQSALEQAIFHFSG---------QQLTTTTAGR 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH+ + + + W+ AL ++ + I V ++ +FD R Sbjct: 51 TDAGVHATGQVAHVDF---IKNWQTYTVRDALNAYLQKQ-GEEIAVLNVQNVPDNFDARF 106 Query: 653 ECLYREYFY 679 + R Y + Sbjct: 107 SAIKRHYLF 115
>Q9Z9J0:TRUA_BACHD tRNA pseudouridine synthase A - Bacillus halodurans| Length = 263 Score = 42.4 bits (98), Expect = 0.007 Identities = 38/132 (28%), Positives = 55/132 (41%), Gaps = 2/132 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 KR+ L+V Y G+++ G Q Q + + T++ LES + N K + S Sbjct: 2 KRIGLKVAYDGTDFAGYQIQPN---ERTVQGELESVL--------KNIHKGMSIRVTASG 50 Query: 470 RTDKGVHSLATMISL--KMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH+ ++ + P W IAL NS LP +I V F Sbjct: 51 RTDTGVHARGQIVHFDTSLSFPVDRWP-----IAL----NSQLPADICVLEAADVPADFH 101 Query: 644 VRRECLYREYFY 679 R +EY Y Sbjct: 102 ARYSAKTKEYRY 113
>Q5JI92:TRUA_PYRKO tRNA pseudouridine synthase A - Pyrococcus kodakaraensis| (Thermococcus kodakaraensis) Length = 267 Score = 42.0 bits (97), Expect = 0.009 Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 3/169 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ LRV Y GS + G Q+Q G T+E + + K GI+ES +K ++ +SR Sbjct: 2 KLALRVAYDGSAFYGFQRQ---PGVRTVEGEIIKVLQKL-GIIESP----EKNDFKGASR 53 Query: 473 TDKGVHSLATMIS-LKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVR 649 TD+GV + ++S + E PD +A +N +L D + V I F R Sbjct: 54 TDRGVSAFFNVVSFVPSERPD---------LARPEVLNHHLSD-VWVLGIAEVPDDFHPR 103 Query: 650 RECLYREYFYLLPAEIIGIKS--SCSSGEVEEHLIEFNNILKGFEGNHP 790 ++ Y Y L E + + C+S V H +F+ K G P Sbjct: 104 FWAKFKTYRYYLVNEGFDLSAMRECASLFVGRH--DFSAFAKLEPGRDP 150
>Q8KDR7:TRUA_CHLTE tRNA pseudouridine synthase A - Chlorobium tepidum| Length = 247 Score = 42.0 bits (97), Expect = 0.009 Identities = 47/174 (27%), Positives = 72/174 (41%), Gaps = 5/174 (2%) Frame = +2 Query: 287 KKRVVLRVGYVGSEYRGLQKQRD--LSGDSTIESVLESAIFKAGGILESNYGKLQKVGWE 460 K+ + +++ Y G+ Y G Q+Q ++ IE VLE + + V + Sbjct: 5 KRTIKMQIEYDGTGYSGWQRQPGDVVTVQGEIERVLERIM-------------QEPVSID 51 Query: 461 RSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSF 640 + RTD GVH+ + S P P G L NS LP I++ ++ A SF Sbjct: 52 GAGRTDSGVHARRQVASFATCSP------MPLG-RLIYSANSLLPSTIRINAMRQAPESF 104 Query: 641 DVRRECLYREYFYLL---PAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPF 793 R REY Y L P+ I + CS G+ + + N + G H F Sbjct: 105 HARFSATSREYRYFLLEHPSAIDSRFAGCSHGKPD--VGAMNRLALMLIGTHDF 156
>P57295:TRUA_BUCAI tRNA pseudouridine synthase A - Buchnera aphidicola subsp.| Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) Length = 266 Score = 42.0 bits (97), Expect = 0.009 Identities = 38/132 (28%), Positives = 57/132 (43%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 K L V Y GS Y G Q+Q+ L ++ I KA I+ ++ K+ + Sbjct: 7 KTFALGVEYDGSYYHGWQRQKILPS-------IQEEIEKALSIIANH-----KIDVVCAG 54 Query: 470 RTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVR 649 RTD GVHS+ +I K + K I +NS L +NI V + +F R Sbjct: 55 RTDAGVHSIGQVIHFKTTANRK---KSSWSIG----VNSYLSENISVVWVKEVTENFHAR 107 Query: 650 RECLYREYFYLL 685 + R Y Y++ Sbjct: 108 YSAITRSYRYII 119
>Q663A0:TRUA_BORGA tRNA pseudouridine synthase A - Borrelia garinii| Length = 246 Score = 42.0 bits (97), Expect = 0.009 Identities = 51/204 (25%), Positives = 84/204 (41%), Gaps = 15/204 (7%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 K+++ + Y GS Y G Q Q TI+ +E A+ K +KV S Sbjct: 2 KKILAEITYDGSIYHGFQIQPT---KPTIQGEIEKALMKINK---------KKVKIHSSG 49 Query: 470 RTDKGVHSLATMIS--LKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTDKGVH+ +I+ + + I +K + I L N +IK+ + + SF Sbjct: 50 RTDKGVHAKKQIITFDININIQLNNLKKALNAILLKN--------SIKILKLKYMKNSFH 101 Query: 644 VRRECLYREYFYLLPAEIIGIKSSCSSGEVEEHLI-------EFNNILKGFEGNHPFHNY 802 R R+Y Y I+ + + H + N + K GNH F + Sbjct: 102 PRFNAQKRKYSY----RILNSNNYYPWEGYQAHYVNKKLNISNLNQMAKILIGNHDFTTF 157 Query: 803 T-----ARAKYRKV-LAGAHRRAK 856 + +++K+R + LA +R K Sbjct: 158 SCIKDKSKSKFRHIYLAKFKKRGK 181
>Q8U2C1:TRUA_PYRFU tRNA pseudouridine synthase A - Pyrococcus furiosus| Length = 266 Score = 41.6 bits (96), Expect = 0.012 Identities = 38/139 (27%), Positives = 64/139 (46%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 RV L++ Y G+++ G Q+Q ++ TIE + A+ AG E+ ++ +SR Sbjct: 2 RVALKIAYDGTKFHGFQRQPNVR---TIEGEILRALKDAGIEFEN---------FKSASR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD+GV + +I+L E D I +NS + D + ++ I F R Sbjct: 50 TDRGVSARGNVIALSTE---------DDRIKNPMVLNSRMSD-VWIWGIAEVPEDFHPRF 99 Query: 653 ECLYREYFYLLPAEIIGIK 709 + Y Y LP+ + IK Sbjct: 100 WANTKVYRYYLPSLGMNIK 118
>Q7MB17:TRUA_PHOLL tRNA pseudouridine synthase A - Photorhabdus luminescens subsp.| laumondii Length = 264 Score = 41.6 bits (96), Expect = 0.012 Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y GS Y G Q+Q+++ +++ LE A+ K + + + R Sbjct: 2 KIALGIEYDGSRYYGWQRQQEVK---SVQGCLEEALSKVAD---------EPISVFCAGR 49 Query: 473 TDKGVHSLATMISLKMEIP--DRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH+ ++ + + D AW +N +LP +I V + F Sbjct: 50 TDAGVHATGQVVHFETSVQRKDAAWTMG---------VNVHLPPDIAVRWVKTVDEGFHA 100 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 101 RFSATARRYRYII 113
>Q5FGS1:TRUA_EHRRG tRNA pseudouridine synthase A - Ehrlichia ruminantium (strain| Gardel) Length = 246 Score = 41.6 bits (96), Expect = 0.012 Identities = 44/177 (24%), Positives = 72/177 (40%), Gaps = 4/177 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R + + Y GS + G QKQ S ++I+ +LE AIFK + YG + R Sbjct: 2 RYKIVIEYDGSNFIGWQKQNHNS--NSIQEILEKAIFKFSKQHVTVYG---------AGR 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDN-IKVFSILPAQRSFDVR 649 TD GVH+L + + D + + N IN +L + I V + F R Sbjct: 51 TDAGVHALGQVAHFDL-------TTDFETYIVRNAINYHLISHAIAVVHVEKTDTDFHAR 103 Query: 650 RECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILKG---FEGNHPFHNYTAR 811 R Y Y + + + + + N++K +GNH F ++ A+ Sbjct: 104 FSAKRRYYLYKIVNRYSPLTIDRNRAWLVHTPLNVENMIKAVCYIKGNHNFSSFRAK 160 Score = 35.0 bits (79), Expect = 1.1 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 1136 FVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIK 1246 ++++ I +SF+ HQ+R +VGT V +G P + IK Sbjct: 182 YIDINISAISFLHHQVRIIVGTLVECGKGYFPPEHIK 218
>Q8XLQ0:TRUA1_CLOPE tRNA pseudouridine synthase A 1 - Clostridium perfringens| Length = 248 Score = 41.6 bits (96), Expect = 0.012 Identities = 34/133 (25%), Positives = 58/133 (43%), Gaps = 1/133 (0%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGD-STIESVLESAIFKAGGILESNYGKLQKVGWERS 466 + + + + Y GS+Y+G QKQ + ST++ LE + K ++Q +G Sbjct: 2 RNIKITLDYDGSKYKGWQKQNQKGSNVSTVQDKLEKVLTKMTS------EEIQLIG---C 52 Query: 467 SRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 RTD GVH+ + + K + + +IN LP++I+V I A F Sbjct: 53 GRTDSGVHAKNYVANFKTNSLMTLEQ-------IIEYINEYLPEDIRVTEIREASERFHA 105 Query: 647 RRECLYREYFYLL 685 R + Y Y + Sbjct: 106 RFNVKSKTYEYTI 118
>Q6GEL6:TRUA_STAAR tRNA pseudouridine synthase A - Staphylococcus aureus (strain| MRSA252) Length = 264 Score = 41.2 bits (95), Expect = 0.015 Identities = 31/131 (23%), Positives = 57/131 (43%), Gaps = 2/131 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+++ + Y G+ + G Q Q++ T++ E + + + V SSR Sbjct: 2 RILVEIAYQGNNFLGFQIQQN---GRTVQQQFEKLLQRI---------HKRHVRIHPSSR 49 Query: 473 TDKGVHSLATMISLK--MEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD+GVH++ + IP W+ +N LPD+I V +++ F Sbjct: 50 TDRGVHAIQQYFHFDTDLNIPMSQWQYA---------MNRTLPDDIYVNNVVTVDDDFHC 100 Query: 647 RRECLYREYFY 679 R +C+ + Y Y Sbjct: 101 RYDCVGKRYRY 111
>Q7MBB9:TRUA_GLOVI tRNA pseudouridine synthase A - Gloeobacter violaceus| Length = 304 Score = 41.2 bits (95), Expect = 0.015 Identities = 35/133 (26%), Positives = 55/133 (41%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ LRV Y+G + G Q Q G T++ LE A + V + + R Sbjct: 16 RLALRVQYLGGHFFGWQWQ---PGQRTVQQCLEEATERIAR---------HPVRYHAAGR 63 Query: 473 TDKGVHSLATMISLKM--EIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH+ ++ ++ W + +NS LPD+I V + + Sbjct: 64 TDTGVHASGQVVHFDTHKKLAPETWVRG---------LNSLLPDDIAVRAAAYVSDHWHA 114 Query: 647 RRECLYREYFYLL 685 R L+REY Y + Sbjct: 115 RFTALWREYRYCI 127
>Q5HBA4:TRUA_EHRRW tRNA pseudouridine synthase A - Ehrlichia ruminantium (strain| Welgevonden) Length = 246 Score = 41.2 bits (95), Expect = 0.015 Identities = 44/177 (24%), Positives = 72/177 (40%), Gaps = 4/177 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R + + Y GS++ G QKQ S ++I+ +LE AIFK YG + R Sbjct: 2 RYKIVIEYDGSDFIGWQKQNHNS--NSIQEILEKAIFKFSKQHVIVYG---------AGR 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDN-IKVFSILPAQRSFDVR 649 TD GVH+L + + D + + N IN +L + I V + F R Sbjct: 51 TDAGVHALGQVAHFDL-------TTDFETYIVRNAINYHLISHAIAVVHVEKTDTDFHAR 103 Query: 650 RECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILKG---FEGNHPFHNYTAR 811 R Y Y + + + + + N++K +GNH F ++ A+ Sbjct: 104 FSAKRRYYLYKIVNRYSPLTIDRNRAWLVHTPLNVENMIKAVCYIKGNHNFSSFRAK 160 Score = 35.0 bits (79), Expect = 1.1 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 1136 FVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIK 1246 ++++ I +SF+ HQ+R +VGT V +G P + IK Sbjct: 182 YIDINISAISFLHHQVRIIVGTLVECGKGYFPPEHIK 218
>Q7U363:TRUA_BORPE tRNA pseudouridine synthase A - Bordetella pertussis| Length = 270 Score = 41.2 bits (95), Expect = 0.015 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 4/135 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAI--FKAGGILESNYGKLQKVGWERS 466 R+ L + Y GS ++G Q Q T++ +E+A+ F GG V + Sbjct: 3 RIALGLAYDGSAWQGWQTQPH---GVTVQDQVEAALASFAGGG---------GPVATVCA 50 Query: 467 SRTDKGVHSLATMISLKMEIP--DRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSF 640 RTD GVH+ +I L ++ D +W + +N+ LP +I V P +F Sbjct: 51 GRTDTGVHAAMQVIHLDTDLQRRDESWVRG---------VNAFLPPSIVVQWARPVSEAF 101 Query: 641 DVRRECLYREYFYLL 685 R R Y YLL Sbjct: 102 HARFSARSRTYVYLL 116
>Q7U376:TRUA_BORPA tRNA pseudouridine synthase A - Bordetella parapertussis| Length = 270 Score = 41.2 bits (95), Expect = 0.015 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 4/135 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAI--FKAGGILESNYGKLQKVGWERS 466 R+ L + Y GS ++G Q Q T++ +E+A+ F GG V + Sbjct: 3 RIALGLAYDGSAWQGWQTQPH---GVTVQDQVEAALASFAGGG---------GPVATVCA 50 Query: 467 SRTDKGVHSLATMISLKMEIP--DRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSF 640 RTD GVH+ +I L ++ D +W + +N+ LP +I V P +F Sbjct: 51 GRTDTGVHAAMQVIHLDTDLQRRDESWVRG---------VNAFLPPSIVVQWARPVSEAF 101 Query: 641 DVRRECLYREYFYLL 685 R R Y YLL Sbjct: 102 HARFSARSRTYVYLL 116
>Q7U386:TRUA_BORBR tRNA pseudouridine synthase A - Bordetella bronchiseptica| (Alcaligenes bronchisepticus) Length = 270 Score = 41.2 bits (95), Expect = 0.015 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 4/135 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAI--FKAGGILESNYGKLQKVGWERS 466 R+ L + Y GS ++G Q Q T++ +E+A+ F GG V + Sbjct: 3 RIALGLAYDGSAWQGWQTQPH---GVTVQDQVEAALASFAGGG---------GPVATVCA 50 Query: 467 SRTDKGVHSLATMISLKMEIP--DRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSF 640 RTD GVH+ +I L ++ D +W + +N+ LP +I V P +F Sbjct: 51 GRTDTGVHAAMQVIHLDTDLQRRDESWVRG---------VNAFLPPSIVVQWARPVSEAF 101 Query: 641 DVRRECLYREYFYLL 685 R R Y YLL Sbjct: 102 HARFSARSRTYVYLL 116
>Q5P1J2:TRUA_AZOSE tRNA pseudouridine synthase A - Azoarcus sp. (strain EbN1)| (Aromatoleum aromaticum (strain EbN1)) Length = 264 Score = 41.2 bits (95), Expect = 0.015 Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+VL V Y GS + G Q Q + T++ LE+AI G + ++ +L G R Sbjct: 2 RIVLGVEYAGSAFEGFQSQ---AHGRTVQDHLEAAI----GHIAAHPVRLHCAG-----R 49 Query: 473 TDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH+ A ++ E P+ W + +NS L + V A F Sbjct: 50 TDAGVHATAQVVHFDTESVRPNSGWVRG---------VNSRLSSPVVVRWATEAGDGFHA 100 Query: 647 RRECLYREYFYLL 685 R + R Y Y+L Sbjct: 101 RFCAVSRRYRYIL 113
>Q9KTA4:TRUA_VIBCH tRNA pseudouridine synthase A - Vibrio cholerae| Length = 264 Score = 40.8 bits (94), Expect = 0.020 Identities = 34/131 (25%), Positives = 55/131 (41%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L + Y G+ Y G Q+QR++ +++ LE A+ K V + + R Sbjct: 2 RIALGIEYDGTHYYGWQRQREVK---SVQEALEKALSKIAN---------HPVEVQCAGR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH ++ D E+ +A N+NLP +I V + F R Sbjct: 50 TDAGVHGTGQVVHF-----DTTAERQM--VAWTMGANANLPKDIAVRWAMAVPDEFHARF 102 Query: 653 ECLYREYFYLL 685 R Y Y++ Sbjct: 103 SATARRYRYVI 113
>Q65TC8:TRUA_MANSM tRNA pseudouridine synthase A - Mannheimia succiniciproducens| (strain MBEL55E) Length = 263 Score = 40.8 bits (94), Expect = 0.020 Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y G Y G Q+Q + ++++ LE A+ ++ +K+ + R Sbjct: 2 KIALGIEYNGKNYFGWQRQEKVH---SVQAELEKAL---------SFVANEKIEVFCAGR 49 Query: 473 TDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH ++ + P++AW A N+NLPD+I V F Sbjct: 50 TDSGVHGTGQVVHFETNAIRPEKAW---------AFGTNANLPDDIAVRWAKEVPDDFHA 100 Query: 647 RRECLYREYFYLL 685 R R Y Y+L Sbjct: 101 RFSATARRYRYVL 113
>Q9HNP6:TRUA_HALSA tRNA pseudouridine synthase A - Halobacterium salinarium| (Halobacterium halobium) Length = 266 Score = 40.8 bits (94), Expect = 0.020 Identities = 44/171 (25%), Positives = 65/171 (38%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R RV Y G Y G Q+Q D+ ST+ L A+ + + + G+ + R Sbjct: 3 RRAFRVAYDGRPYHGFQRQPDV---STVAGELFGALRRL-----DVFDGAKPPGYAAAGR 54 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GV + A ++ AW PD A LPD I+V++ A F Sbjct: 55 TDAGVSARAQTVAFDAP----AW-LTPDAFTGA------LPDPIQVWAHADAPPEFHATH 103 Query: 653 ECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNYT 805 + + R Y Y A ++G ++ G H FHN T Sbjct: 104 DAVARTYVYYWYAPDSRATDDRAAGALDR-----------LTGTHDFHNLT 143
>Q92SH4:TRUA_RHIME tRNA pseudouridine synthase A - Rhizobium meliloti (Sinorhizobium| meliloti) Length = 247 Score = 40.4 bits (93), Expect = 0.026 Identities = 33/132 (25%), Positives = 54/132 (40%), Gaps = 3/132 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R L V Y GS+Y G Q+Q +++ +E A+ + V + R Sbjct: 3 RYRLTVEYDGSDYVGWQRQ---DNGPSVQGAIEKAVLSL---------TRETVSIRGAGR 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLP---DNIKVFSILPAQRSFD 643 TD GVH+ + L + R W+ L N +N++L + + + + A FD Sbjct: 51 TDSGVHARGQVAHLDLT---REWKS----YTLQNALNAHLALAGERVSILDVAEAPGDFD 103 Query: 644 VRRECLYREYFY 679 R + R Y Y Sbjct: 104 ARFSAIRRHYLY 115
>P70973:TRUA_BACSU tRNA pseudouridine synthase A - Bacillus subtilis| Length = 247 Score = 40.4 bits (93), Expect = 0.026 Identities = 37/136 (27%), Positives = 56/136 (41%), Gaps = 2/136 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ + Y G + G Q Q G T++ LE A+ +L + ++ V S R Sbjct: 2 RLKCTISYDGHLFNGYQVQ---PGKRTVQDELEKAL----AVLHKSKDRIPVVS---SGR 51 Query: 473 TDKGVHSLATMISLK--MEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH+ +I + IP W +N+ LPD+I V A F Sbjct: 52 TDSGVHAAGQVIHFDTPLSIPAERWPYA---------LNALLPDDIAVKQAEIADDGFHA 102 Query: 647 RRECLYREYFYLLPAE 694 R + +EY Y + E Sbjct: 103 RFSAVKKEYRYFVYTE 118
>Q5WLN0:TRUA_BACSK tRNA pseudouridine synthase A - Bacillus clausii (strain KSM-K16)| Length = 261 Score = 40.0 bits (92), Expect = 0.034 Identities = 35/134 (26%), Positives = 59/134 (44%), Gaps = 3/134 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ ++ Y G+ + G Q Q G T++S +E A+ K +V S R Sbjct: 3 RMACKLSYDGTAFAGYQVQ---PGKRTVQSEVERAL--------QEIHKGARVPVVASGR 51 Query: 473 TDKGVHSLATMISLKMEI---PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 TD GVH+ ++ E+ P+R W + +N++LPD+I V + + F Sbjct: 52 TDAGVHACGQVLHFDTELTIAPER-W---------VSALNTHLPDDIVVTNAAMVEPDFH 101 Query: 644 VRRECLYREYFYLL 685 R +EY Y + Sbjct: 102 ARYGAQAKEYRYYI 115
>Q65P74:TRUA_BACLD tRNA pseudouridine synthase A - Bacillus licheniformis (strain DSM| 13 / ATCC 14580) Length = 247 Score = 40.0 bits (92), Expect = 0.034 Identities = 35/133 (26%), Positives = 55/133 (41%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ + Y G + G Q Q G TI+ LE A L++ + +++ S R Sbjct: 2 RMKCTISYDGHLFYGYQVQ---PGQRTIQDELEKA-------LQTLHKAKERIPVVSSGR 51 Query: 473 TDKGVHSLATMISLK--MEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH++ I + IP+ W +N+ LPD+I V F Sbjct: 52 TDSGVHAVGQTIHFDSPLSIPEAKWPYA---------LNALLPDDISVRKAEAVNDQFHA 102 Query: 647 RRECLYREYFYLL 685 R +EY Y++ Sbjct: 103 RFSAKRKEYRYMI 115
>Q5E455:TRUA_VIBF1 tRNA pseudouridine synthase A - Vibrio fischeri (strain ATCC 700601| / ES114) Length = 262 Score = 39.7 bits (91), Expect = 0.044 Identities = 34/133 (25%), Positives = 53/133 (39%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L + Y G+EY G Q+QRD+ ++++ LE A+ + + + R Sbjct: 2 RIALCIEYDGAEYYGWQRQRDV---NSVQEELEKALTIVAN---------EPIEVHCAGR 49 Query: 473 TDKGVHSLATMISLKMEIPDR--AWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH ++ + AW N+NLP NI V F Sbjct: 50 TDAGVHGTGQVVHFDTTSSRKLAAWMMG---------ANANLPKNIAVRWAKEVNEDFHA 100 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 101 RFTATARRYRYII 113
>Q73KE3:TRUA_TREDE tRNA pseudouridine synthase A - Treponema denticola| Length = 268 Score = 39.7 bits (91), Expect = 0.044 Identities = 35/139 (25%), Positives = 56/139 (40%), Gaps = 5/139 (3%) Frame = +2 Query: 278 STRKKRVVLRVGYVGSEYRGLQKQRDLSGDS--TIESVLESAIFKAGGILESNYGKLQKV 451 S +K ++L + Y G+ + G QKQ ++ T++ LE A+ K + Sbjct: 4 SQNQKNILLTISYDGTNFCGWQKQTKEGAETFRTVQGELEKALTKI---------HKHPI 54 Query: 452 GWERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANF---INSNLPDNIKVFSIL 622 S RTD GVH+ ++ +I + +NF +NS LP +I+V Sbjct: 55 ETNGSGRTDSGVHAARQAVNFFCDI---------KSMRASNFLPALNSILPKDIRVMDAA 105 Query: 623 PAQRSFDVRRECLYREYFY 679 R L R Y Y Sbjct: 106 EVSPLLHARFNALSRTYRY 124
>Q8ZNB9:TRUA_SALTY tRNA pseudouridine synthase A - Salmonella typhimurium| Length = 270 Score = 39.7 bits (91), Expect = 0.044 Identities = 32/139 (23%), Positives = 58/139 (41%), Gaps = 2/139 (1%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 +S+ ++ L + Y GS+Y G Q+Q ++ +++ LE A+ + + + Sbjct: 5 QSSAVYKIALGIEYDGSKYYGWQRQNEV---RSVQEKLEKALSQVAN---------EPIN 52 Query: 455 WERSSRTDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPA 628 + RTD GVH ++ + D AW +N+NLP +I V + Sbjct: 53 VFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLG---------VNANLPGDIAVRWVKTV 103 Query: 629 QRSFDVRRECLYREYFYLL 685 F R R Y Y++ Sbjct: 104 PDDFHARFSATARRYRYII 122
>P65846:TRUA_MYCTU tRNA pseudouridine synthase A - Mycobacterium tuberculosis| Length = 297 Score = 39.7 bits (91), Expect = 0.044 Identities = 37/149 (24%), Positives = 59/149 (39%), Gaps = 10/149 (6%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESA---IFKAGGILESNYGKLQKVGWER 463 R+ L + Y G+++ G Q G T+ L++A IF+ V Sbjct: 23 RLRLDIAYDGTDFAGWAAQ---VGQRTVAGDLDAALTTIFRT------------PVRLRA 67 Query: 464 SSRTDKGVHSLATMI-------SLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSIL 622 + RTD GVH+ + +L P DP+ + L + LP ++++ I Sbjct: 68 AGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEFLPLLRRLGRFLPADVRILDIT 127 Query: 623 PAQRSFDVRRECLYREYFYLLPAEIIGIK 709 A FD R L R Y Y L G++ Sbjct: 128 RAPAGFDARFSALRRHYVYRLSTAPYGVE 156
>Q9X796:TRUA_MYCLE tRNA pseudouridine synthase A - Mycobacterium leprae| Length = 286 Score = 39.7 bits (91), Expect = 0.044 Identities = 40/150 (26%), Positives = 63/150 (42%), Gaps = 11/150 (7%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLES--AIFKAGGILESNYGKLQKVGWERS 466 R+ L + Y G+++ G Q +G T+ + E+ +F+ V + Sbjct: 12 RLRLDIAYDGTDFAGWAVQ---AGQRTVAGLDEAFTTVFRT------------PVRLRAA 56 Query: 467 SRTDKGVHSLATMISLKMEIPDRAWEK---------DPDGIALANFINSNLPDNIKVFSI 619 RTD GVH AT ++IP A K DP+ + L ++ LP +++V I Sbjct: 57 GRTDTGVH--ATGQVAHVDIPGTALSKANPRSPHTGDPEFLPLLRRLSRLLPVDVRVLDI 114 Query: 620 LPAQRSFDVRRECLYREYFYLLPAEIIGIK 709 A FD R L R Y Y L G++ Sbjct: 115 ACAPVGFDARFSALRRHYRYRLSTAPYGVQ 144
>P65847:TRUA_MYCBO tRNA pseudouridine synthase A - Mycobacterium bovis| Length = 297 Score = 39.7 bits (91), Expect = 0.044 Identities = 37/149 (24%), Positives = 59/149 (39%), Gaps = 10/149 (6%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESA---IFKAGGILESNYGKLQKVGWER 463 R+ L + Y G+++ G Q G T+ L++A IF+ V Sbjct: 23 RLRLDIAYDGTDFAGWAAQ---VGQRTVAGDLDAALTTIFRT------------PVRLRA 67 Query: 464 SSRTDKGVHSLATMI-------SLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSIL 622 + RTD GVH+ + +L P DP+ + L + LP ++++ I Sbjct: 68 AGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEFLPLLRRLGRFLPADVRILDIT 127 Query: 623 PAQRSFDVRRECLYREYFYLLPAEIIGIK 709 A FD R L R Y Y L G++ Sbjct: 128 RAPAGFDARFSALRRHYVYRLSTAPYGVE 156
>Q45557:TRUA_BACSV tRNA pseudouridine synthase A - Bacillus sp. (strain KSM-64)| Length = 244 Score = 39.7 bits (91), Expect = 0.044 Identities = 43/178 (24%), Positives = 76/178 (42%), Gaps = 3/178 (1%) Frame = +2 Query: 302 LRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDK 481 L + Y G Y+G Q+ + G++TI+ +E+ + + G K++ +G S RTD Sbjct: 6 LMIQYDGGRYKGWQRLGN--GENTIQGKIETVLSEMVG------RKIEIIG---SGRTDA 54 Query: 482 GVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECL 661 GVH+L + ++K+ E + ++N LP +I V + F R Sbjct: 55 GVHALGQVANVKLSENFTVKE-------VKEYLNRYLPHDISVTEVTLVPDRFHSRYNAK 107 Query: 662 YREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILKG---FEGNHPFHNYTARAKYRK 826 + Y Y + E E + +N++K F G H F + + AK +K Sbjct: 108 DKTYLYKIWNEDYTHPFMRKYSLHIEKKLHIDNMVKASQLFVGEHDFTAF-SNAKSKK 164 Score = 34.3 bits (77), Expect = 1.9 Identities = 21/71 (29%), Positives = 34/71 (47%) Frame = +2 Query: 1112 LQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVLPIAP 1291 +Q + G F+++ +CG F+ + +RKMVGT + V G + + L R A Sbjct: 176 IQDNQG--FIDIRVCGDGFLYNMVRKMVGTLIEVGLGEKEPEQVLTILESKDRSQAGFAD 233 Query: 1292 SEVLILRDNSF 1324 + L L SF Sbjct: 234 ATGLYLEGISF 244
>Q8CML6:TRUA_STAES tRNA pseudouridine synthase A - Staphylococcus epidermidis (strain| ATCC 12228) Length = 267 Score = 39.3 bits (90), Expect = 0.058 Identities = 30/131 (22%), Positives = 59/131 (45%), Gaps = 2/131 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+++ + Y G+++ G Q Q+ T++ E + + + ++ ++ SSR Sbjct: 2 RILVEIAYQGNQFLGFQIQQQ---GRTVQQQFEKILKR----MHKHHVRIHP-----SSR 49 Query: 473 TDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD+GVH+ E I ++ W+ +N LPD+I V ++ F Sbjct: 50 TDRGVHAYQQFFHFDTELNIDNKQWQYA---------MNRALPDDIYVKNVRNVDEYFHC 100 Query: 647 RRECLYREYFY 679 R +C+ + Y Y Sbjct: 101 RYDCVGKRYRY 111
>Q5HM30:TRUA_STAEQ tRNA pseudouridine synthase A - Staphylococcus epidermidis (strain| ATCC 35984 / RP62A) Length = 267 Score = 39.3 bits (90), Expect = 0.058 Identities = 30/131 (22%), Positives = 59/131 (45%), Gaps = 2/131 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+++ + Y G+++ G Q Q+ T++ E + + + ++ ++ SSR Sbjct: 2 RILVEIAYQGNQFLGFQIQQQ---GRTVQQQFEKILKR----MHKHHVRIHP-----SSR 49 Query: 473 TDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD+GVH+ E I ++ W+ +N LPD+I V ++ F Sbjct: 50 TDRGVHAYQQFFHFDTELNIDNKQWQYA---------MNRALPDDIYVKNVRNVDEYFHC 100 Query: 647 RRECLYREYFY 679 R +C+ + Y Y Sbjct: 101 RYDCVGKRYRY 111
>Q8Z500:TRUA_SALTI tRNA pseudouridine synthase A - Salmonella typhi| Length = 270 Score = 39.3 bits (90), Expect = 0.058 Identities = 32/139 (23%), Positives = 58/139 (41%), Gaps = 2/139 (1%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 +S+ ++ L + Y GS+Y G Q+Q ++ +++ LE A+ + + + Sbjct: 5 QSSPVYKIALGIEYDGSKYYGWQRQNEVR---SVQEKLEKALSQVAN---------EPIN 52 Query: 455 WERSSRTDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPA 628 + RTD GVH ++ + D AW +N+NLP +I V + Sbjct: 53 VFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLG---------VNANLPGDIAVRWVKTV 103 Query: 629 QRSFDVRRECLYREYFYLL 685 F R R Y Y++ Sbjct: 104 PDDFHARFSATARRYRYII 122
>Q5PCV6:TRUA_SALPA tRNA pseudouridine synthase A - Salmonella paratyphi-a| Length = 270 Score = 39.3 bits (90), Expect = 0.058 Identities = 32/139 (23%), Positives = 58/139 (41%), Gaps = 2/139 (1%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 +S+ ++ L + Y GS+Y G Q+Q ++ +++ LE A+ + + + Sbjct: 5 QSSPVYKIALGIEYDGSKYYGWQRQNEVR---SVQEKLEKALSQVAN---------EPIN 52 Query: 455 WERSSRTDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPA 628 + RTD GVH ++ + D AW +N+NLP +I V + Sbjct: 53 VFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLG---------VNANLPGDIAVRWVKTV 103 Query: 629 QRSFDVRRECLYREYFYLL 685 F R R Y Y++ Sbjct: 104 PDDFHARFSATARRYRYII 122
>Q8XXX8:TRUA_RALSO tRNA pseudouridine synthase A - Ralstonia solanacearum (Pseudomonas| solanacearum) Length = 274 Score = 39.3 bits (90), Expect = 0.058 Identities = 34/131 (25%), Positives = 56/131 (42%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L + Y G+ + G Q Q +T++ VLE+A+ + G+ + + R Sbjct: 3 RIALGIQYDGAAFSGWQSQPH---GNTVQDVLEAALREFAGVA---------LPTTVAGR 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH+L ++ L E+ +DP + N+ LP + V F R Sbjct: 51 TDAGVHALGQVVHLDTEL-----VRDP--FSWVRGTNAFLPPTVAVRWAQAMPEDFHARF 103 Query: 653 ECLYREYFYLL 685 R Y+Y L Sbjct: 104 SAHRRTYYYAL 114
>Q9UZZ3:TRUA_PYRAB tRNA pseudouridine synthase A - Pyrococcus abyssi| Length = 263 Score = 39.3 bits (90), Expect = 0.058 Identities = 32/133 (24%), Positives = 63/133 (47%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 RV ++ Y G+ + G Q+Q +L T+E + A+ +G I+ S++ + +SR Sbjct: 2 RVAFKIAYDGTRFHGFQRQPNLR---TVEGEIIKALNNSG-IMYSDF--------KSASR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD+GV +L ++++ E D AL + + +++ + S + + F R Sbjct: 50 TDRGVSALGNVVAITTE----------DEKALNPMVLNARLEDVWILSAIEVPQDFHPRF 99 Query: 653 ECLYREYFYLLPA 691 + Y Y LP+ Sbjct: 100 WAKSKVYRYYLPS 112
>Q6LNU5:TRUA_PHOPR tRNA pseudouridine synthase A - Photobacterium profundum| (Photobacterium sp. (strain SS9)) Length = 261 Score = 39.3 bits (90), Expect = 0.058 Identities = 40/177 (22%), Positives = 71/177 (40%), Gaps = 5/177 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L + Y G++Y G Q+Q D+ +++ LE A+ + + + R Sbjct: 2 RIALGIEYDGAKYCGWQRQVDVD---SVQERLEKALSHIAN---------KPIAVFCAGR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH ++ +++ D +A +N++LP +I V F R Sbjct: 50 TDTGVHGTGQVVHFDVDV-------DRQMVAWTIGVNAHLPRDISVRWATQVSDDFHARF 102 Query: 653 ECLYREYFYL-----LPAEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNYTA 808 R Y Y+ L I G+ S G ++E + + + G H F + A Sbjct: 103 SATARRYRYIIYNSALRPAIFGVGVSHYHGHLDEK--KMHEAAQYLVGEHDFTSVRA 157
>P57861:TRUA_PASMU tRNA pseudouridine synthase A - Pasteurella multocida| Length = 264 Score = 39.3 bits (90), Expect = 0.058 Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y G Y G Q+Q +++ +++ LE AI ++ Q + R Sbjct: 2 KIALGIQYNGKNYCGWQRQENVA---SVQEQLEKAI---------SFVANQPCQIFCAGR 49 Query: 473 TDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH+ ++ + + ++AW +N+NLPD+I V F Sbjct: 50 TDSGVHATGQVVHFETDAIRAEKAWSFG---------VNANLPDDISVSWAKCVTDDFHA 100 Query: 647 RRECLYREYFYLL 685 R R Y Y+L Sbjct: 101 RFSATARRYRYIL 113
>Q7NAQ9:TRUA_MYCGA tRNA pseudouridine synthase A - Mycoplasma gallisepticum| Length = 262 Score = 39.3 bits (90), Expect = 0.058 Identities = 49/187 (26%), Positives = 77/187 (41%), Gaps = 11/187 (5%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 K V++ + Y G+++ G Q D T++S L+ A+ I ES K+ S Sbjct: 22 KNVLINISYHGTKFHGYAVQNDYE---TVQSKLQDAL---AWIYES------KIYVNASG 69 Query: 470 RTDKGVHSLATMISLKMEIPDR-AWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 RTDKGVH++ IS I DR + EK L +N + + I R+F Sbjct: 70 RTDKGVHAINQYIS--FYIDDRISLEK------LREILNRYGQNKWYIKWIKEVDRNFHA 121 Query: 647 RRECLYREYFYLLPAEIIGIKSSCSSGE-------VEEHLIEFNNILKG---FEGNHPFH 796 R + Y YL+ C++ + ++FN I K EG H F Sbjct: 122 RFSAKAKTYLYLI--------DYCANNPLFYDHAWIVNFQLDFNLIEKAIPILEGTHNFW 173 Query: 797 NYTARAK 817 +++ K Sbjct: 174 SFSTADK 180
>Q87MP1:TRUA_VIBPA tRNA pseudouridine synthase A - Vibrio parahaemolyticus| Length = 264 Score = 38.5 bits (88), Expect = 0.098 Identities = 32/131 (24%), Positives = 57/131 (43%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L + Y G+ Y G Q+QR++ +++ LE A+ I+ ++ ++Q G R Sbjct: 2 RIALGIEYNGTNYFGWQRQREVK---SVQEELEKAL----SIVANHPVEVQCAG-----R 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH ++ + + +A N+N+P +I V F R Sbjct: 50 TDAGVHGTGQVVHFDTNVNRKM-------VAWTMGANANMPSDIAVRWAKEVPDDFHARF 102 Query: 653 ECLYREYFYLL 685 R Y Y++ Sbjct: 103 SATARRYRYII 113
>Q83QR3:TRUA_SHIFL tRNA pseudouridine synthase A - Shigella flexneri| Length = 270 Score = 38.5 bits (88), Expect = 0.098 Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y GS+Y G Q+Q ++ +++ LE A+ + + + + R Sbjct: 11 KIALGIEYDGSKYYGWQRQNEVR---SVQEKLEKALSQVAN---------EPITVFCAGR 58 Query: 473 TDKGVHSLATMISLKM--EIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH ++ + + D AW +N+NLP +I V + F Sbjct: 59 TDAGVHGTGQVVHFETTAQRKDAAWTLG---------VNANLPGDIAVRWVKAVPDDFHA 109 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 110 RFSATARRYRYII 122
>Q5WX34:TRUA_LEGPL tRNA pseudouridine synthase A - Legionella pneumophila (strain| Lens) Length = 262 Score = 38.5 bits (88), Expect = 0.098 Identities = 38/131 (29%), Positives = 54/131 (41%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L V Y GS+Y G Q Q +G TI+ +E A+ K + + R Sbjct: 2 RIALVVEYDGSQYHGWQAQ---TGLHTIQQAVEFALSKVAD---------SSISVVCAGR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH+ +I EKD A + NS LP +I V +F R Sbjct: 50 TDTGVHATNQVIHFDC-------EKDRSIRAWIHGANSFLPKDICVKWGKEMPENFHARY 102 Query: 653 ECLYREYFYLL 685 + R Y Y++ Sbjct: 103 SAVSRRYRYVI 113
>P65844:TRUA_ECOL6 tRNA pseudouridine synthase A - Escherichia coli O6| Length = 270 Score = 38.5 bits (88), Expect = 0.098 Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y GS+Y G Q+Q ++ +++ LE A+ + + + + R Sbjct: 11 KIALGIEYDGSKYYGWQRQNEVR---SVQEKLEKALSQVAN---------EPITVFCAGR 58 Query: 473 TDKGVHSLATMISLKM--EIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH ++ + + D AW +N+NLP +I V + F Sbjct: 59 TDAGVHGTGQVVHFETTAQRKDAAWTLG---------VNANLPGDIAVRWVKAVPDDFHA 109 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 110 RFSATARRYRYII 122
>P65845:TRUA_ECO57 tRNA pseudouridine synthase A - Escherichia coli O157:H7| Length = 270 Score = 38.5 bits (88), Expect = 0.098 Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y GS+Y G Q+Q ++ +++ LE A+ + + + + R Sbjct: 11 KIALGIEYDGSKYYGWQRQNEVR---SVQEKLEKALSQVAN---------EPITVFCAGR 58 Query: 473 TDKGVHSLATMISLKM--EIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH ++ + + D AW +N+NLP +I V + F Sbjct: 59 TDAGVHGTGQVVHFETTAQRKDAAWTLG---------VNANLPGDIAVRWVKAVPDDFHA 109 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 110 RFSATARRYRYII 122
>O24712:TRUA_SYNP6 tRNA pseudouridine synthase A - Synechococcus sp. (strain ATCC| 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) Length = 294 Score = 38.1 bits (87), Expect = 0.13 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 4/136 (2%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 +R+ L + Y+G + G Q+Q +++ LESAI G V + + Sbjct: 14 QRIALVIQYLGQGFCGWQRQ---PRQRSVQGELESAIAAVVG---------HPVSVQSAG 61 Query: 470 RTDKGVHSLATMISLK--MEIPDRAWEKDPDGIALANFINSNL-PD-NIKVFSILPAQRS 637 RTD GVH+ A + + IP W + +N L PD NI+ +I+PA + Sbjct: 62 RTDTGVHAAAQVAHFETTSPIPAHRW---------PSVLNGRLTPDLNIRAAAIVPA--N 110 Query: 638 FDVRRECLYREYFYLL 685 + R YR Y Y + Sbjct: 111 WHARFSASYRRYRYTI 126
>P07649:TRUA_ECOLI tRNA pseudouridine synthase A - Escherichia coli| Length = 270 Score = 38.1 bits (87), Expect = 0.13 Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y GS+Y G Q+Q ++ +++ LE A+ + + + + R Sbjct: 11 KIALGIEYDGSKYYGWQRQNEVR---SVQEKLEKALSQVAN---------EPITVFCAGR 58 Query: 473 TDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH ++ + D AW +N+NLP +I V + F Sbjct: 59 TDAGVHGTGQVVHFETTALRKDAAWTLG---------VNANLPGDIAVRWVKTVPDDFHA 109 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 110 RFSATARRYRYII 122
>Q73G93:TRUA_WOLPM tRNA pseudouridine synthase A - Wolbachia pipientis wMel| Length = 245 Score = 37.7 bits (86), Expect = 0.17 Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 1/130 (0%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R + V Y GS + G QKQ+ + ++I+ +E+AIF G +KV R Sbjct: 2 RYKITVEYNGSNFSGWQKQQHSA--NSIQEKIENAIFNFSG---------EKVTLYCGGR 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPD-NIKVFSILPAQRSFDVR 649 TD GVH+L + M EK+ + + N IN +L I V + +F R Sbjct: 51 TDAGVHALGQVAHFDM-------EKEFELYRIRNAINYHLKSIPIVVLNAEVVDDAFHAR 103 Query: 650 RECLYREYFY 679 R Y Y Sbjct: 104 FSAKKRYYEY 113
>P60353:TRUA_SPIKU tRNA pseudouridine synthase A - Spiroplasma kunkelii| Length = 260 Score = 37.7 bits (86), Expect = 0.17 Identities = 50/188 (26%), Positives = 80/188 (42%), Gaps = 5/188 (2%) Frame = +2 Query: 296 VVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRT 475 ++L + Y G +Y G KQ++ TI+ LE A F GI QK+ +S+T Sbjct: 4 LLLSIEYDGYDYSGWVKQKNAR---TIQGELEKAFF---GICH------QKIWTLGASKT 51 Query: 476 DKGVHSLATMISLKMEIPDRAWEKDPDGIALANFI---NSNLPDNIKVFSILPAQRSFDV 646 D GVH+ + +K+ R LA FI + LP NI + +F V Sbjct: 52 DAGVHACDQKVLVKLTFQPR---------HLAFFIKTVSQTLPPNINIKGYQFVAENFSV 102 Query: 647 RRECLYREYFYLLPAEIIGIKSSCSSGEVEE--HLIEFNNILKGFEGNHPFHNYTARAKY 820 R +EY Y + + + + +V ++ + + I + F G H F Y A K Sbjct: 103 -RTVKVKEYVYTINDQEYDLFNHRYELKVNAPLNVKKLHQISQIFVGTHDF-AYFAGVKP 160 Query: 821 RKVLAGAH 844 + +A H Sbjct: 161 TEDIATVH 168
>O58941:TRUA_PYRHO tRNA pseudouridine synthase A - Pyrococcus horikoshii| Length = 262 Score = 37.7 bits (86), Expect = 0.17 Identities = 32/133 (24%), Positives = 60/133 (45%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 +V L++ Y G+++ G Q+Q ++ T+E + A+ +G + + +SR Sbjct: 2 KVALKIAYDGTKFHGFQRQPNVR---TVEGEIIKALNNSGIMFNE---------LKSASR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TDKGV +L ++++ E + I +N+ L D + V S + F R Sbjct: 50 TDKGVSALGNVVAITTE---------DERITNPMILNAKLKD-VWVLSAVKVPSDFHPRF 99 Query: 653 ECLYREYFYLLPA 691 + Y Y LP+ Sbjct: 100 WARSKVYRYYLPS 112
>Q5PAN6:TRUA_ANAMM tRNA pseudouridine synthase A - Anaplasma marginale (strain St.| Maries) Length = 247 Score = 37.7 bits (86), Expect = 0.17 Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 2/126 (1%) Frame = +2 Query: 308 VGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDKGV 487 V Y G+ + G Q+Q+ ++G S ES+ E AI++ Q V + RTD GV Sbjct: 7 VEYDGTAFIGWQRQKGVAGRSVQESI-EDAIYRL---------SQQCVTVFAAGRTDAGV 56 Query: 488 HSLATMI--SLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECL 661 H+L ++ L + D + AL +++ S D + + S+ A F R Sbjct: 57 HALGQVVHFDLNTSLQDYVIKN-----ALNHYLRS---DMVSILSLEEAAEGFHARFSAK 108 Query: 662 YREYFY 679 R Y Y Sbjct: 109 KRHYMY 114
>Q6MDE3:TRUA2_PARUW tRNA pseudouridine synthase A 2 - Protochlamydia amoebophila| (strain UWE25) Length = 262 Score = 37.7 bits (86), Expect = 0.17 Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 5/141 (3%) Frame = +2 Query: 278 STRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGW 457 S + + L++ Y G Y G QK ++E L++++ + IL+ + Sbjct: 12 SKSMQNIKLKIAYDGQAYFGWQKT---PAGPSVEKTLQNSLEQ---ILQHT------ISL 59 Query: 458 ERSSRTDKGVHSLATMISL--KMEIPDRAWEKDPDGIALANFI---NSNLPDNIKVFSIL 622 + +SRTDKGVH+ +++ I D L FI NS LP ++++ S Sbjct: 60 QAASRTDKGVHARGQIVNFLTTKSITD-----------LQKFILSLNSLLPTDLRILSAE 108 Query: 623 PAQRSFDVRRECLYREYFYLL 685 +F C+ +EY Y + Sbjct: 109 KMPSTFHPTLNCVAKEYCYYI 129
>Q8P7R5:TRUA_XANCP tRNA pseudouridine synthase A - Xanthomonas campestris pv.| campestris Length = 257 Score = 37.4 bits (85), Expect = 0.22 Identities = 36/131 (27%), Positives = 56/131 (42%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R L V Y GSE++G Q+ + G S +++ L++A+ +Q V + R Sbjct: 2 RYALGVEYDGSEFQGWQQLGEHGGPS-VQATLQAALSSVAD------APIQVVC---AGR 51 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH ++ D ++P G L + LP ++ V +PA F R Sbjct: 52 TDAGVHGECQVVHF-----DSDARREPRGWMLGT--TARLPPSVAVRWCVPAAEDFHARF 104 Query: 653 ECLYREYFYLL 685 R Y Y L Sbjct: 105 SARARRYRYRL 115
>Q5LNR0:TRUA_SILPO tRNA pseudouridine synthase A - Silicibacter pomeroyi| Length = 262 Score = 37.4 bits (85), Expect = 0.22 Identities = 32/132 (24%), Positives = 58/132 (43%), Gaps = 1/132 (0%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R L+V Y+G+ + G Q+Q+DL +++ +E+A+ + LE + G R Sbjct: 3 RYALKVEYLGTPFAGWQRQKDL---PSVQGAIETALAR----LEPGPHTIAAAG-----R 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNL-PDNIKVFSILPAQRSFDVR 649 TD GVH L + + +D D L+ +N +L P + + + + R Sbjct: 51 TDAGVHGLGQVAHCDL-------TRDWDPFRLSEALNYHLKPQPVAITAAARVAEDWHAR 103 Query: 650 RECLYREYFYLL 685 R+Y + L Sbjct: 104 FSATERQYLFRL 115
>Q5ZVY6:TRUA_LEGPH tRNA pseudouridine synthase A - Legionella pneumophila subsp.| pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) Length = 262 Score = 37.4 bits (85), Expect = 0.22 Identities = 37/131 (28%), Positives = 54/131 (41%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L V Y GS+Y G Q Q +G TI+ +E A+ K + + R Sbjct: 2 RIALVVEYDGSQYHGWQAQ---TGLHTIQQAVEFALSKVAD---------SSISVVCAGR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH+ +I EKD A + N+ LP +I V +F R Sbjct: 50 TDTGVHATNQVIHFDC-------EKDRSIRAWIHGANTFLPKDICVKWGKEMPENFHARY 102 Query: 653 ECLYREYFYLL 685 + R Y Y++ Sbjct: 103 SAVSRRYRYVI 113
>Q5X5Q4:TRUA_LEGPA tRNA pseudouridine synthase A - Legionella pneumophila (strain| Paris) Length = 262 Score = 37.4 bits (85), Expect = 0.22 Identities = 37/131 (28%), Positives = 54/131 (41%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L V Y GS+Y G Q Q +G TI+ +E A+ K + + R Sbjct: 2 RIALVVEYDGSQYHGWQAQ---TGLHTIQQAVEFALSKVAD---------SSISVVCAGR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH+ +I EKD A + N+ LP +I V +F R Sbjct: 50 TDTGVHATNQVIHFDC-------EKDRSIRAWIHGANTFLPKDICVKWGKEMPENFHARY 102 Query: 653 ECLYREYFYLL 685 + R Y Y++ Sbjct: 103 SAVSRRYRYVI 113
>Q83WJ5:TRUA_BURCE tRNA pseudouridine synthase A - Burkholderia cepacia (Pseudomonas| cepacia) Length = 270 Score = 37.4 bits (85), Expect = 0.22 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 17/95 (17%) Frame = +2 Query: 1025 QARWLHEPNDND--RLSASHF---RDILTCSCGELQSSSGVQ------------FVELTI 1153 +A W+H P D+D R +A+H D E QS + V+ F+ Sbjct: 126 RAGWIHTPLDDDAMRAAAAHLLGEHDFSAFRSSECQSKTPVKHLYEIDIRRVGHFLHFRF 185 Query: 1154 CGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLA 1258 +F+ H +R ++G VAV RG P D + LA Sbjct: 186 RANAFLHHMVRNLMGCLVAVGRGRYPADWVADVLA 220 Score = 32.3 bits (72), Expect = 7.1 Identities = 32/131 (24%), Positives = 52/131 (39%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ L + Y G+ + G Q Q +T++ LE A+ + + + + R Sbjct: 2 RIALGIQYDGAAFCGWQAQPH---GNTVQDALERALAEFARV---------PLHTTVAGR 49 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH L ++ E+ DRA + N+ LP + V +F R Sbjct: 50 TDTGVHGLGQVVHFDTEL-DRA------DFSWVRGTNAFLPPTVAVQWAKSMPDAFHARF 102 Query: 653 ECLYREYFYLL 685 R Y+Y L Sbjct: 103 SAFERTYYYAL 113
>O28544:TRUA_ARCFU tRNA pseudouridine synthase A - Archaeoglobus fulgidus| Length = 265 Score = 37.4 bits (85), Expect = 0.22 Identities = 36/161 (22%), Positives = 67/161 (41%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 + ++ Y G + G Q Q D T+E + +A+ + G ++ + R Sbjct: 3 KFAFKIAYFGDNFHGSQFQPD---QRTVEGEVINALRRLG---------VENPRLRSAGR 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH+ +IS E D+ + + +N+ LP++I ++ FD RR Sbjct: 51 TDAGVHAYGQVISFYSE--DKIFPR---------MLNAELPEDITAWAWAKVSEDFDPRR 99 Query: 653 ECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNILKGF 775 R Y Y++ I + + + + +F+N K F Sbjct: 100 -AKSRVYTYVMYGSDYDISAMRKAVKELIGVHDFSNFTKKF 139
>Q1RKH3:TRUA_RICBR tRNA pseudouridine synthase A - Rickettsia bellii (strain RML369-C)| Length = 245 Score = 37.0 bits (84), Expect = 0.29 Identities = 23/68 (33%), Positives = 36/68 (52%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R + V Y+G+ G Q+Q SG +++ +LE AI+K G + +G S R Sbjct: 3 RYKISVEYLGTNLAGWQRQ---SGVMSVQQILEEAIYKFSGEQVTLFG---------SGR 50 Query: 473 TDKGVHSL 496 TD GVH++ Sbjct: 51 TDAGVHAI 58
>Q6MQH6:TRUA_BDEBA tRNA pseudouridine synthase A - Bdellovibrio bacteriovorus| Length = 262 Score = 37.0 bits (84), Expect = 0.29 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 3/134 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 +V V Y G+ + G QKQ+ ++ V+E A+ K +K+ S R Sbjct: 4 KVRFTVAYDGTGFCGWQKQKP-EDQISVAQVIEEALSKVFN---------EKITLFASGR 53 Query: 473 TDKGVHSLATM--ISLKMEI-PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 TD GVH+L + S +I P++ W+ L +NS+LP +I A F Sbjct: 54 TDAGVHALNQVCHFSTHRKIDPNKKWD-------LCWALNSHLPPSIVAKKAWIAPDDFH 106 Query: 644 VRRECLYREYFYLL 685 ++ Y YL+ Sbjct: 107 ATLSATHKTYRYLI 120
>Q6HPM7:TRUA1_BACHK tRNA pseudouridine synthase A 1 - Bacillus thuringiensis subsp.| konkukian Length = 247 Score = 37.0 bits (84), Expect = 0.29 Identities = 33/129 (25%), Positives = 54/129 (41%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ V Y G + G Q Q T++ +E A+ K + G+L +V + S R Sbjct: 3 RIKCTVAYDGMHFCGYQIQPQ---HRTVQQEIEKALQKL------HKGELVRV--QASGR 51 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD VH+ +I + W+ +N +N+ LPD+I + + F R Sbjct: 52 TDSTVHAKGQVIHFDTPLSLEEWQ-------WSNALNTMLPDDIVITQVEKKTEEFHARY 104 Query: 653 ECLYREYFY 679 +EY Y Sbjct: 105 GVERKEYRY 113
>Q63H59:TRUA1_BACCZ tRNA pseudouridine synthase A 1 - Bacillus cereus (strain ZK /| E33L) Length = 247 Score = 37.0 bits (84), Expect = 0.29 Identities = 33/129 (25%), Positives = 54/129 (41%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ V Y G + G Q Q T++ +E A+ K + G+L +V + S R Sbjct: 3 RIKCTVAYDGMHFCGYQIQPQ---HRTVQQEIEKALQKL------HKGELVRV--QASGR 51 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD VH+ +I + W+ +N +N+ LPD+I + + F R Sbjct: 52 TDSTVHAKGQVIHFDTPLSLEEWQ-------WSNALNTMLPDDIVITQVEKKTEEFHARY 104 Query: 653 ECLYREYFY 679 +EY Y Sbjct: 105 GVERKEYRY 113
>Q814C2:TRUA1_BACCR tRNA pseudouridine synthase A 1 - Bacillus cereus (strain ATCC| 14579 / DSM 31) Length = 247 Score = 37.0 bits (84), Expect = 0.29 Identities = 33/129 (25%), Positives = 55/129 (42%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ V Y G + G Q Q + T++ +E A+ K + G+L +V + S R Sbjct: 3 RIKCTVAYDGMHFCGYQIQPN---HRTVQQEIEKALQKL------HKGELVRV--QASGR 51 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD VH+ +I + W+ +N +N+ LPD+I + + F R Sbjct: 52 TDSTVHAKGQVIHFDTPLSLEEWQ-------WSNALNTMLPDDIVIRQVEKKTEEFHARY 104 Query: 653 ECLYREYFY 679 +EY Y Sbjct: 105 GVEKKEYRY 113
>Q6I4Q2:TRUA1_BACAN tRNA pseudouridine synthase A 1 - Bacillus anthracis| Length = 247 Score = 37.0 bits (84), Expect = 0.29 Identities = 33/129 (25%), Positives = 54/129 (41%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ V Y G + G Q Q T++ +E A+ K + G+L +V + S R Sbjct: 3 RIKCTVAYDGMHFCGYQIQPQ---HRTVQQEIEKALQKL------HKGELVRV--QASGR 51 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD VH+ +I + W+ +N +N+ LPD+I + + F R Sbjct: 52 TDSTVHAKGQVIHFDTPLSLEEWQ-------WSNALNTMLPDDIVITQVEKKTEEFHARY 104 Query: 653 ECLYREYFY 679 +EY Y Sbjct: 105 GVERKEYRY 113
>Q8N0Z8:PUSL1_HUMAN tRNA pseudouridine synthase-like 1 - Homo sapiens (Human)| Length = 303 Score = 37.0 bits (84), Expect = 0.29 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 1/134 (0%) Frame = +2 Query: 287 KKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERS 466 + R ++ YVG+++ G+ R +++ LE A + + + V + S Sbjct: 11 RARYLVYFQYVGTDFNGVAAVRGTQRAVGVQNYLEEAAERLNSV--------EPVRFTIS 62 Query: 467 SRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNL-PDNIKVFSILPAQRSFD 643 SRTD GVH+L+ + +++ R+ LA +N++L I+V F Sbjct: 63 SRTDAGVHALSN--AAHLDVQRRSGRPPFPPEVLAEALNTHLRHPAIRVLRAFRVPSDFH 120 Query: 644 VRRECLYREYFYLL 685 R R Y Y L Sbjct: 121 ARHAATSRTYLYRL 134
>Q73F64:TRUA1_BACC1 tRNA pseudouridine synthase A 1 - Bacillus cereus (strain ATCC| 10987) Length = 247 Score = 36.6 bits (83), Expect = 0.37 Identities = 33/129 (25%), Positives = 54/129 (41%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ V Y G + G Q Q T++ +E A+ K + G+L +V + S R Sbjct: 3 RIKCTVAYDGMHFCGYQIQPQ---HRTVQQEIEKALQKL------HKGELVRV--QASGR 51 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD VH+ +I + W+ + N +N+ LPD+I + + F R Sbjct: 52 TDSTVHAKGQVIHFDTPLSLEEWQWN-------NALNTMLPDDIVITQVEKKTEEFHARY 104 Query: 653 ECLYREYFY 679 +EY Y Sbjct: 105 GVERKEYRY 113
>Q5GXR2:TRUA_XANOR tRNA pseudouridine synthase A - Xanthomonas oryzae pv. oryzae| Length = 257 Score = 36.2 bits (82), Expect = 0.49 Identities = 37/131 (28%), Positives = 56/131 (42%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R L V Y GSE++G Q+ + G S +++ L++A+ +Q V + R Sbjct: 2 RYALGVEYDGSEFQGWQQLGEHGGPS-VQASLQAALSSVAD------APVQVVC---AGR 51 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH ++ D ++P G L + LP +I V +PA F R Sbjct: 52 TDAGVHGECQVVHF-----DSDAHREPRGWMLGT--TARLPPSIAVRWCVPAAADFHARF 104 Query: 653 ECLYREYFYLL 685 R Y Y L Sbjct: 105 SARARRYRYRL 115
>P45291:TRUA_HAEIN tRNA pseudouridine synthase A - Haemophilus influenzae| Length = 269 Score = 36.2 bits (82), Expect = 0.49 Identities = 32/133 (24%), Positives = 53/133 (39%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y G Y G Q+Q + +++ LE A+ +K+ + R Sbjct: 2 KIALGIEYNGQNYYGWQRQEKVR---SVQEELEKALSHIAN---------EKIEIFCAGR 49 Query: 473 TDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GV ++ + P++AW A N++LPD+I V F Sbjct: 50 TDSGVSGTGQVVHFETNAVRPEKAW---------AFGTNAHLPDDIAVSWAKQVDDEFHA 100 Query: 647 RRECLYREYFYLL 685 R R Y Y+L Sbjct: 101 RFSATARRYRYIL 113
>Q5FPX3:TRUA_GLUOX tRNA pseudouridine synthase A - Gluconobacter oxydans| (Gluconobacter suboxydans) Length = 275 Score = 36.2 bits (82), Expect = 0.49 Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 1/138 (0%) Frame = +2 Query: 275 ESTRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVG 454 E T R LR+ Y G+ Y G QKQ D ++I+ ++E+A S + + V Sbjct: 16 EPTGLNRWALRIEYDGTGYLGWQKQND---GTSIQGLIEAA--------ASKLVRNRPVP 64 Query: 455 WERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNL-PDNIKVFSILPAQ 631 + RTD GVH+ +I L + PD A D + + + +L P + V Sbjct: 65 SITAGRTDAGVHAAGMVIHL--DFPDDA---PIDARQIRDGMGYHLKPHRVVVLETAKVG 119 Query: 632 RSFDVRRECLYREYFYLL 685 ++ R +R Y Y + Sbjct: 120 PEWNARFSATWRSYRYTI 137
>P60349:TRUA_CORDI tRNA pseudouridine synthase A - Corynebacterium diphtheriae| Length = 288 Score = 36.2 bits (82), Expect = 0.49 Identities = 45/216 (20%), Positives = 89/216 (41%), Gaps = 5/216 (2%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQK-VGWERSS 469 R+ L + Y G+++ G +Q D S T++ ++E + LQ+ + + Sbjct: 7 RIRLDLAYDGTDFHGWARQGD-SDLRTVQKIIEDTLTLV----------LQRPIDLTVAG 55 Query: 470 RTDKGVHSLATMISLKME---IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSF 640 RTD GVH+ + ++ + R+ DP L + +PD++++ ++ F Sbjct: 56 RTDAGVHATGQVAHFDVDPAALETRSIAGDP--ARLIRRLARLMPDDVRIHNMSFVPAEF 113 Query: 641 DVRRECLYREYFYLLPAEIIGIKSSCSSGEVE-EHLIEFNNILKGFEGNHPFHNYTARAK 817 D R L R Y Y + G + + ++ + + + H++ A K Sbjct: 114 DARFSALRRHYVYRVTTHPRGALPTRARDTAHWPRSVDISAMQAAADALIGMHDFAAFCK 173 Query: 818 YRKVLAGAHRRAKETSTAAHSIPSEMVADQSTSSAD 925 YR+ A R +E + S P E ++ +AD Sbjct: 174 YREG-ASTIRDLQEFTWHDVSTPQEPQLYEAHVTAD 208
>Q97EL1:TRUA_CLOAB tRNA pseudouridine synthase A - Clostridium acetobutylicum| Length = 244 Score = 36.2 bits (82), Expect = 0.49 Identities = 38/134 (28%), Positives = 58/134 (43%), Gaps = 2/134 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 K V L + Y G+ Y G QKQ+++ T++ +E I + G +K+ S Sbjct: 2 KNVKLTLEYDGTNYCGWQKQKNVV---TVQEEVEKIIGEITG---------EKIDVIGCS 49 Query: 470 RTDKGVHSLATMISLKME--IPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH+ A + K IP P+ L +NS LPD+I + F Sbjct: 50 RTDSGVHAKAYTCNFKTNTVIP-------PEKFYLV--LNSVLPDDIVALNSEEVPMDFH 100 Query: 644 VRRECLYREYFYLL 685 R + + Y Y + Sbjct: 101 SRFDNKGKTYSYTI 114
>Q8XHV5:TRUA2_CLOPE tRNA pseudouridine synthase A 2 - Clostridium perfringens| Length = 244 Score = 36.2 bits (82), Expect = 0.49 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 2/134 (1%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 + + L + Y G+ Y G QKQ +TI+ +E AI K ++V SS Sbjct: 2 RNIKLTIEYDGTSYFGWQKQPI---GNTIQQKVEEAIKKV---------TKEEVEILGSS 49 Query: 470 RTDKGVHSLATMISLK--MEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFD 643 RTD GVH+ A + + K IP + ++ +NS LP +I + + F Sbjct: 50 RTDSGVHAKAYVANFKTNSNIPGKNFKA---------ALNSKLPKDIVIINSEEVAEDFH 100 Query: 644 VRRECLYREYFYLL 685 R + Y Y + Sbjct: 101 ARYMTTGKTYCYTI 114
>Q6HNW5:TRUA2_BACHK tRNA pseudouridine synthase A 2 - Bacillus thuringiensis subsp.| konkukian Length = 245 Score = 36.2 bits (82), Expect = 0.49 Identities = 31/126 (24%), Positives = 56/126 (44%) Frame = +2 Query: 302 LRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDK 481 L + Y G+ ++G Q+ + D+TI+ +ES I + G G SRTD Sbjct: 6 LTIQYDGARFKGWQRLGN--NDNTIQGKIESVISEMVGKETEIIG---------CSRTDA 54 Query: 482 GVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECL 661 GVH+L + + + + EK + + ++N LP++I + ++ F R Sbjct: 55 GVHALNQVANFQSD------EKLVEH-KVKKYLNQYLPNDISITNVEEVHNRFHARYNSK 107 Query: 662 YREYFY 679 + Y Y Sbjct: 108 VKTYLY 113
>Q813Z9:TRUA2_BACCR tRNA pseudouridine synthase A 2 - Bacillus cereus (strain ATCC| 14579 / DSM 31) Length = 245 Score = 36.2 bits (82), Expect = 0.49 Identities = 30/126 (23%), Positives = 60/126 (47%) Frame = +2 Query: 302 LRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDK 481 L + Y G+ ++G Q+ + D+TI+ +ES I + G +++ +G SRTD Sbjct: 6 LTIQYDGARFKGWQRLGN--NDNTIQGKIESVISEMVG------KEIEIIG---CSRTDA 54 Query: 482 GVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECL 661 GVH+L + + + + ++ E + ++N LP++I + ++ F R Sbjct: 55 GVHALNQVANFQSD--EKLVEH-----KVKKYLNQYLPNDISITNVEEVHDRFHARYNSK 107 Query: 662 YREYFY 679 + Y Y Sbjct: 108 AKTYLY 113
>Q8PJ25:TRUA_XANAC tRNA pseudouridine synthase A - Xanthomonas axonopodis pv. citri| Length = 257 Score = 35.8 bits (81), Expect = 0.64 Identities = 37/131 (28%), Positives = 56/131 (42%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R L V Y GSE++G Q+ + G S +++ L++A+ +Q V + R Sbjct: 2 RYALGVEYDGSEFQGWQQLGEHGGPS-VQASLQAALSSVAD------APVQVVC---AGR 51 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TD GVH ++ D ++P G L + LP +I V +PA F R Sbjct: 52 TDAGVHGECQVVHF-----DSDARREPRGWMLGT--TARLPPSIAVRWCVPAADDFHARF 104 Query: 653 ECLYREYFYLL 685 R Y Y L Sbjct: 105 SARARRYRYRL 115
>Q6A6S8:TRUA_PROAC tRNA pseudouridine synthase A - Propionibacterium acnes| Length = 279 Score = 35.8 bits (81), Expect = 0.64 Identities = 34/128 (26%), Positives = 57/128 (44%) Frame = +2 Query: 302 LRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDK 481 L + Y G+ + G Q D T++ LE+ I + +L + Q + RTD Sbjct: 6 LDIAYDGANFSGWATQPDRR---TVQGELETWIPR---VLRLD----QPTPLTVAGRTDA 55 Query: 482 GVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECL 661 GVH+ + + ++PD D A+ ++ L ++ V S+ P +FD R L Sbjct: 56 GVHARGQVAHV--DLPDNV-----DTSAMLRRLSRVLTPDVVVKSVRPVPSTFDARFSAL 108 Query: 662 YREYFYLL 685 +R Y Y L Sbjct: 109 WRRYVYRL 116
>Q63GF1:TRUA2_BACCZ tRNA pseudouridine synthase A 2 - Bacillus cereus (strain ZK /| E33L) Length = 245 Score = 35.8 bits (81), Expect = 0.64 Identities = 30/126 (23%), Positives = 60/126 (47%) Frame = +2 Query: 302 LRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDK 481 L + Y G+ ++G Q+ + D+TI+ +ES I + G +++ +G SRTD Sbjct: 6 LTIQYDGARFKGWQRLGN--NDNTIQGKIESVISEMIG------KEIEIIG---CSRTDA 54 Query: 482 GVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECL 661 GVH+L + + + + ++ E + ++N LP++I + ++ F R Sbjct: 55 GVHALNQVANFQSD--EKLVEH-----KVKKYLNQYLPNDISITNVEEVHDRFHARYNSK 107 Query: 662 YREYFY 679 + Y Y Sbjct: 108 AKTYLY 113
>Q7M9U3:TRUA_WOLSU tRNA pseudouridine synthase A - Wolinella succinogenes| Length = 253 Score = 35.4 bits (80), Expect = 0.83 Identities = 36/127 (28%), Positives = 55/127 (43%) Frame = +2 Query: 314 YVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDKGVHS 493 Y GS + G Q Q++ + ++ L+ + + G KV + S RTD+GVH Sbjct: 10 YDGSAFFGSQIQKE---EPSVALALQRGL--------KSMGIASKVRF--SGRTDRGVH- 55 Query: 494 LATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECLYREY 673 AT ++ E+P K D +N L ++V + P + D R E R Y Sbjct: 56 -ATRQAVSFEVP----YKKSDWGYFKEELNKKLFPYLRVRRLYPIREGLDPRFEAKSRAY 110 Query: 674 FYLLPAE 694 YLL E Sbjct: 111 RYLLSEE 117
>Q8CWQ1:TRUA_STRR6 tRNA pseudouridine synthase A - Streptococcus pneumoniae (strain ATCC| BAA-255 / R6) Length = 249 Score = 35.0 bits (79), Expect = 1.1 Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 1/62 (1%) Frame = +2 Query: 1133 QFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSR-IVLPIAPSEVLIL 1309 QF+ T G F+ QIR MVGT + + +P + I L L K R + P A L L Sbjct: 183 QFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQIDLILEKKDRQLAGPTAAPNGLYL 242 Query: 1310 RD 1315 ++ Sbjct: 243 KE 244
>Q97PL0:TRUA_STRPN tRNA pseudouridine synthase A - Streptococcus pneumoniae| Length = 249 Score = 35.0 bits (79), Expect = 1.1 Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 1/62 (1%) Frame = +2 Query: 1133 QFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSR-IVLPIAPSEVLIL 1309 QF+ T G F+ QIR MVGT + + +P + I L L K R + P A L L Sbjct: 183 QFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQIDLILEKKDRQLAGPTAAPNGLYL 242 Query: 1310 RD 1315 ++ Sbjct: 243 KE 244
>Q8DWH1:TRUA_STRMU tRNA pseudouridine synthase A - Streptococcus mutans| Length = 249 Score = 35.0 bits (79), Expect = 1.1 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Frame = +2 Query: 1088 ILTCSCGELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFS 1267 + T S ++ F+ T G F+ Q+R MVGT + + G +P D I L Sbjct: 168 VRTISRATVEKDDKTGFLIFTFTGSGFLYKQVRNMVGTLLKIGNGRMPIDQIDRILESGD 227 Query: 1268 R-IVLPIAPSEVLILRD 1315 R + P A S L L++ Sbjct: 228 RSLAGPTAASNGLYLKE 244
>Q92FZ9:TRUA_RICCN tRNA pseudouridine synthase A - Rickettsia conorii| Length = 245 Score = 35.0 bits (79), Expect = 1.1 Identities = 21/68 (30%), Positives = 36/68 (52%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R + + Y+G++ G Q+Q +G +++ +LE AI+K G +G S R Sbjct: 3 RYKITIEYLGTDLAGWQRQ---AGVMSVQQILEEAIYKFSGEQVILFG---------SGR 50 Query: 473 TDKGVHSL 496 TD GVH++ Sbjct: 51 TDAGVHAI 58
>Q8CY46:TRUA_BIFLO tRNA pseudouridine synthase A - Bifidobacterium longum| Length = 303 Score = 35.0 bits (79), Expect = 1.1 Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 4/133 (3%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R+ + + Y G + G KQ +L T++ +E A+ K + + + ++ + R Sbjct: 3 RLRIDLAYDGGGFYGWAKQPNLR---TVQGTIEDALHKVLRVPTDDAAEPLRL--TVAGR 57 Query: 473 TDKGVHSLATMISLKM--EIPDRA--WEKDPDGIALANFINSNLPDNIKVFSILPAQRSF 640 TD GVH+ + L + E+ +R P AL + + LP +I + I A F Sbjct: 58 TDTGVHASHQVAHLDVSDEVLNRCVGHMTIPVTEALTRRLKAVLPSDIVIHGIAVAPVGF 117 Query: 641 DVRRECLYREYFY 679 D R L R Y Y Sbjct: 118 DARFSALERTYVY 130
>Q73E17:TRUA2_BACC1 tRNA pseudouridine synthase A 2 - Bacillus cereus (strain ATCC| 10987) Length = 245 Score = 35.0 bits (79), Expect = 1.1 Identities = 30/126 (23%), Positives = 56/126 (44%) Frame = +2 Query: 302 LRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDK 481 L + Y G+ ++G Q+ + D+TI+ +ES I + G G SRTD Sbjct: 6 LTIQYDGARFKGWQRLGN--NDNTIQGKIESVISEMVGKETEIIG---------CSRTDA 54 Query: 482 GVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECL 661 GVH+L + + + + ++ E + ++N LP++I + ++ F R Sbjct: 55 GVHALNQVANFQSD--EKLVEH-----KVKKYLNQYLPNDISITNVEEVHDRFHARYNSK 107 Query: 662 YREYFY 679 + Y Y Sbjct: 108 AKTYLY 113
>Q6I3T8:TRUA2_BACAN tRNA pseudouridine synthase A 2 - Bacillus anthracis| Length = 245 Score = 35.0 bits (79), Expect = 1.1 Identities = 30/126 (23%), Positives = 56/126 (44%) Frame = +2 Query: 302 LRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDK 481 L + Y G+ ++G Q+ + D+TI+ +ES I + G G SRTD Sbjct: 6 LTIQYDGARFKGWQRLGN--NDNTIQGKIESVISEMVGKETEIIG---------CSRTDA 54 Query: 482 GVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECL 661 GVH+L + + + + ++ E + ++N LP++I + ++ F R Sbjct: 55 GVHALNQVANFQSD--EKLVEH-----KVKKYLNQYLPNDISITNVEEVHDRFHARYNSK 107 Query: 662 YREYFY 679 + Y Y Sbjct: 108 AKTYLY 113
>Q6MEE7:TRUA1_PARUW tRNA pseudouridine synthase A 1 - Protochlamydia amoebophila| (strain UWE25) Length = 256 Score = 34.7 bits (78), Expect = 1.4 Identities = 35/128 (27%), Positives = 56/128 (43%) Frame = +2 Query: 302 LRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSRTDK 481 L + Y G+ Y G Q Q + S ++ I +A IL K +KV S RTD Sbjct: 6 LTIAYDGTNYSGWQIQPNASS-------IQQKIQEALCILL----KKEKVVLVGSGRTDA 54 Query: 482 GVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRRECL 661 GVH+ K ++ ++ D L +N LP +I++ ++ P F + + Sbjct: 55 GVHA-------KGQVAHFHFQDYIDLSRLHVSLNGLLPRDIRIKAVEPVSPRFHSQYSAI 107 Query: 662 YREYFYLL 685 +EY Y L Sbjct: 108 RKEYHYYL 115
>Q50291:TRUA_MYCPN tRNA pseudouridine synthase A - Mycoplasma pneumoniae| Length = 243 Score = 34.3 bits (77), Expect = 1.9 Identities = 37/131 (28%), Positives = 57/131 (43%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R + V Y G+ +RG KQ G T++ +E + + YG S R Sbjct: 3 RYLAIVAYNGAPFRGWAKQ---PGYHTVQGQIEQNLALIYQTPINIYG---------SGR 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVRR 652 TDKGVH++ + +++PD K P +A N PD I V +++P F R Sbjct: 51 TDKGVHAINQ--TFHVDLPD----KLPLKQLIAKLNQLNYPD-IFVKALVPVAPRFHARF 103 Query: 653 ECLYREYFYLL 685 + Y YL+ Sbjct: 104 AVKTKVYEYLI 114
>Q59069:TRUA_METJA tRNA pseudouridine synthase A - Methanococcus jannaschii| Length = 259 Score = 34.3 bits (77), Expect = 1.9 Identities = 22/67 (32%), Positives = 35/67 (52%) Frame = +2 Query: 1109 ELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVLPIA 1288 +++ S ++ + I G SF+ + +RK+VG V RG P + I L + R +P Sbjct: 148 DIKISENEFYLTVDIIGESFLWNMVRKIVGALDLVGRGKKPVEWIDKLLDENHREGVPTF 207 Query: 1289 PSEVLIL 1309 P E LIL Sbjct: 208 PPEGLIL 214 Score = 32.0 bits (71), Expect = 9.2 Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 3/122 (2%) Frame = +2 Query: 470 RTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVR 649 RTDKGV +L + +++ +K+P + ++IN+ L D K +L R D Sbjct: 48 RTDKGVSALGNFVVVEL-------KKEP----ILSYINAKLKD--KGIWVL-GYREIDEI 93 Query: 650 RECLYREYFYLLP---AEIIGIKSSCSSGEVEEHLIEFNNILKGFEGNHPFHNYTARAKY 820 + YR Y Y+LP ++ IK K G H FHN + R + Sbjct: 94 PKVKYRHYRYILPNIGYDVDAIKEGA----------------KKMIGTHSFHNLSKRDRT 137 Query: 821 RK 826 ++ Sbjct: 138 KE 139
>Q9ABF0:TRUA_CAUCR tRNA pseudouridine synthase A - Caulobacter crescentus (Caulobacter| vibrioides) Length = 247 Score = 34.3 bits (77), Expect = 1.9 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R L V Y G Y G Q Q L +++ +E+A+ G Q+V + R Sbjct: 3 RYRLLVEYDGRPYAGFQAQATLP---SVQGAIEAAVKAFCG---------QEVRIAAAGR 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLP-DNIKVFSILPAQRSFDVR 649 TD GVH+ ++ + + +KD + N +N++L + + + S A+ + R Sbjct: 51 TDTGVHATGQVVHVDL-------DKDWPAQTVFNALNAHLTREAVSILSAEVAEEGWHAR 103 Query: 650 RECLYREYFY 679 R Y Y Sbjct: 104 FSANERRYLY 113
>P65851:TRUA_STRP8 tRNA pseudouridine synthase A - Streptococcus pyogenes serotype M18| Length = 249 Score = 33.9 bits (76), Expect = 2.4 Identities = 15/45 (33%), Positives = 26/45 (57%) Frame = +2 Query: 1136 FVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSR 1270 F+ T G F+ Q+R MVGT + + G +P + +K+ L+ +R Sbjct: 184 FLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQVKVILSSKNR 228
>Q5XA03:TRUA_STRP6 tRNA pseudouridine synthase A - Streptococcus pyogenes serotype M6| Length = 249 Score = 33.9 bits (76), Expect = 2.4 Identities = 15/45 (33%), Positives = 26/45 (57%) Frame = +2 Query: 1136 FVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSR 1270 F+ T G F+ Q+R MVGT + + G +P + +K+ L+ +R Sbjct: 184 FLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQVKVILSSKNR 228
>Q8K5W2:TRUA_STRP3 tRNA pseudouridine synthase A - Streptococcus pyogenes serotype M3| Length = 249 Score = 33.9 bits (76), Expect = 2.4 Identities = 15/45 (33%), Positives = 26/45 (57%) Frame = +2 Query: 1136 FVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSR 1270 F+ T G F+ Q+R MVGT + + G +P + +K+ L+ +R Sbjct: 184 FLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQVKVILSSKNR 228
>P65850:TRUA_STRP1 tRNA pseudouridine synthase A - Streptococcus pyogenes serotype M1| Length = 249 Score = 33.9 bits (76), Expect = 2.4 Identities = 15/45 (33%), Positives = 26/45 (57%) Frame = +2 Query: 1136 FVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSR 1270 F+ T G F+ Q+R MVGT + + G +P + +K+ L+ +R Sbjct: 184 FLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQVKVILSSKNR 228
>P37610:TAUD_ECOLI Alpha-ketoglutarate-dependent taurine dioxygenase - Escherichia coli| Length = 283 Score = 33.9 bits (76), Expect = 2.4 Identities = 25/106 (23%), Positives = 40/106 (37%), Gaps = 3/106 (2%) Frame = +2 Query: 746 IEFNNILKGFEGNHPFHNYTARAKYRKVLAGAHRRAKETSTAAHSIPSEMVADQSTSSAD 925 + F +L G H F KYRK H+R +E + +V S Sbjct: 140 VPFRQLLSGLRAEHDFRKSFPEYKYRKT-EEEHQRWREAVAKNPPLLHPVVRTHPVSGKQ 198 Query: 926 DEYLN---FPSILDSSAREDNCKMDNPELPQSRVQIQARWLHEPND 1054 ++N I+D S +E + ++ + Q RW +PND Sbjct: 199 ALFVNEGFTTRIVDVSEKESEALLSFLFAHITKPEFQVRWRWQPND 244
>P60352:TRUA_RHOPA tRNA pseudouridine synthase A - Rhodopseudomonas palustris| Length = 248 Score = 33.5 bits (75), Expect = 3.2 Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 1/134 (0%) Frame = +2 Query: 281 TRKKRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWE 460 +R R L + Y G+ + G Q Q L +++ LE+A G +G Sbjct: 2 SRMPRYKLTIEYDGAPFCGWQLQPALP---SVQGALEAAALATCGEAVRVHG-------- 50 Query: 461 RSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNL-PDNIKVFSILPAQRS 637 + RTD GVH+L + + + P RA + L + +N++L P+ + V + + Sbjct: 51 -AGRTDAGVHALGQVAHVDIPKPFRADK-------LRDALNAHLRPNPVAVLAAEIVPDT 102 Query: 638 FDVRRECLYREYFY 679 F+ R + R Y Y Sbjct: 103 FEARFSAVRRHYRY 116
>Q7U335:TRUA_HAEDU tRNA pseudouridine synthase A - Haemophilus ducreyi| Length = 261 Score = 33.5 bits (75), Expect = 3.2 Identities = 31/133 (23%), Positives = 53/133 (39%), Gaps = 2/133 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 +V L + Y GS Y G Q+Q ++ +++ LE A+ K + + R Sbjct: 2 KVALGIEYDGSNYFGWQRQAEVV---SVQQTLEEALSKVTNTTIEVFC---------AGR 49 Query: 473 TDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVH ++ E+ P +W N++L ++I V + F Sbjct: 50 TDSGVHGTGQVVHFDTEVERPLASW---------CFGTNAHLANDIAVKWAVKVAEDFHA 100 Query: 647 RRECLYREYFYLL 685 R R Y Y++ Sbjct: 101 RFSATARRYRYII 113
>P59508:TRUA_BUCBP tRNA pseudouridine synthase A - Buchnera aphidicola subsp.| Baizongia pistaciae Length = 264 Score = 33.5 bits (75), Expect = 3.2 Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 2/160 (1%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 ++ L + Y GS Y G Q Q+ S +++ +E A+ I+ ++ ++ G R Sbjct: 7 KIALGIEYNGSNYHGWQYQKFAS---SVQEKVELAL----SIIANHPVRVTCAG-----R 54 Query: 473 TDKGVHSLATMISLKMEI--PDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDV 646 TD GVHS ++ D+AW N LP +I V F Sbjct: 55 TDAGVHSTGQVVHFCTSSIRNDQAWILGT---------NRYLPKDISVIWKRDVPMHFHA 105 Query: 647 RRECLYREYFYLLPAEIIGIKSSCSSGEVEEHLIEFNNIL 766 R L R Y Y+L +SC S + L ++ IL Sbjct: 106 RYSALSRRYRYIL------YNNSCRSSIFYQGLKFYHRIL 139
>O83802:TRUA_TREPA tRNA pseudouridine synthase A - Treponema pallidum| Length = 280 Score = 33.1 bits (74), Expect = 4.1 Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 3/135 (2%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 ++++LR+ Y G+ + G QKQ +SG ++ + K + QK+ S Sbjct: 5 RKILLRISYDGTRFCGWQKQ--VSGSRERAPSVQGELEKVAEKIHH-----QKIAVIGSG 57 Query: 470 RTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFI---NSNLPDNIKVFSILPAQRSF 640 RTD GVH++ + P R I FI NS LP +I++ Sbjct: 58 RTDSGVHAVGQ--AAHFCTPMR-------NILAYRFIPAFNSLLPHSIRITDAREVSSQL 108 Query: 641 DVRRECLYREYFYLL 685 R + R Y Y L Sbjct: 109 HARFSAVMRTYRYHL 123
>Q9REQ0:TRUA_ZYMMO tRNA pseudouridine synthase A - Zymomonas mobilis| Length = 245 Score = 32.7 bits (73), Expect = 5.4 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 1/130 (0%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSSR 472 R L V + G + G Q+Q+ + ++ +I +AG + +Q G R Sbjct: 3 RYRLTVEFDGRNFMGWQRQKH-------GATIQGSIEEAGASIAGQPTPVQAAG-----R 50 Query: 473 TDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNL-PDNIKVFSILPAQRSFDVR 649 TD GVH LA + + +D L +N+ L P I + S + R Sbjct: 51 TDAGVHGLAMTAHIDV-------ARDFTPFRLMEALNARLKPRPIAILSCEQVDPEWHAR 103 Query: 650 RECLYREYFY 679 C+ R Y Y Sbjct: 104 FSCIGRRYLY 113 Score = 32.0 bits (71), Expect = 9.2 Identities = 17/47 (36%), Positives = 25/47 (53%) Frame = +2 Query: 1139 VELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSLAKFSRIVL 1279 +E+T SF+ HQ+R MVG V V +G D + +L +R L Sbjct: 183 IEITAAARSFLHHQVRSMVGCLVLVGQGQWTADDMTTALEARNRAAL 229
>Q5NVC7:RNF34_PONPY E3 ubiquitin-protein ligase RNF34 - Pongo pygmaeus (Orangutan)| Length = 372 Score = 32.7 bits (73), Expect = 5.4 Identities = 23/101 (22%), Positives = 48/101 (47%) Frame = +2 Query: 791 FHNYTARAKYRKVLAGAHRRAKETSTAAHSIPSEMVADQSTSSADDEYLNFPSILDSSAR 970 F NYTA + G +TS + +P+++ ++ ++++ +D+ + D Sbjct: 180 FSNYTAPSATMSSFQGELMDGDQTSRSG--VPAQVQSEITSANTEDD--DDDDDEDDDDE 235 Query: 971 EDNCKMDNPELPQSRVQIQARWLHEPNDNDRLSASHFRDIL 1093 E+N + NP L + RV+ L +D + +S ++IL Sbjct: 236 EENAEDQNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEIL 276
>Q09587:NHR22_CAEEL Nuclear hormone receptor family member nhr-22 - Caenorhabditis| elegans Length = 579 Score = 32.7 bits (73), Expect = 5.4 Identities = 14/39 (35%), Positives = 19/39 (48%) Frame = -3 Query: 925 ICTGSALVRNHFGGNGMRCCACFFGPSVCSS*NFSILGT 809 +C+ HFGG + CA FF SV S + +GT Sbjct: 98 VCSSPTANTLHFGGRSCKACAAFFRRSVSMSMTYECIGT 136
>P48861:DDC_MANSE Aromatic-L-amino-acid decarboxylase - Manduca sexta (Tobacco| hawkmoth) (Tobacco hornworm) Length = 508 Score = 32.7 bits (73), Expect = 5.4 Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 3/57 (5%) Frame = +2 Query: 1520 SQLDEVRTAYRAWKDDYDRVKMARKNTGSG*YVFIKLI---TKRTRN*TTYPESNVF 1681 S+ E + +W++ DR+ M K+ G+ V IK+I T+RT+N TY + N+F Sbjct: 450 SRFTEESDMHVSWEEIKDRLMMFLKSKGA---VLIKIICSTTRRTKNILTYIKQNIF 503
>Q8CX20:TRUA_STRA5 tRNA pseudouridine synthase A - Streptococcus agalactiae serotype V| Length = 258 Score = 32.3 bits (72), Expect = 7.1 Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 1/70 (1%) Frame = +2 Query: 1109 ELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSL-AKFSRIVLPI 1285 ++Q + + T G F+ Q+R MVGT + + G +P IK L AK + P Sbjct: 175 KIQFEASKNLLIFTFTGNGFLYKQVRNMVGTLLKIGNGRMPISQIKTILQAKNRDLAGPT 234 Query: 1286 APSEVLILRD 1315 A L L++ Sbjct: 235 AAGNGLYLKE 244
>Q8E7Q5:TRUA_STRA3 tRNA pseudouridine synthase A - Streptococcus agalactiae serotype III| Length = 258 Score = 32.3 bits (72), Expect = 7.1 Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 1/70 (1%) Frame = +2 Query: 1109 ELQSSSGVQFVELTICGVSFMLHQIRKMVGTAVAVKRGLLPKDIIKLSL-AKFSRIVLPI 1285 ++Q + + T G F+ Q+R MVGT + + G +P IK L AK + P Sbjct: 175 KIQFEASKNLLIFTFTGNGFLYKQVRNMVGTLLKIGNGRMPISQIKTILQAKNRDLAGPT 234 Query: 1286 APSEVLILRD 1315 A L L++ Sbjct: 235 AAGNGLYLKE 244
>Q49ZT7:HRTB_STAS1 Putative hemin transport system permease protein hrtB -| Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) Length = 350 Score = 32.3 bits (72), Expect = 7.1 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 4/63 (6%) Frame = +2 Query: 1292 SEVLILRDNSFCTRNKQGSIVRPGMQSINESEEIK----KGVMEFYKVALVPELAKFLDE 1459 S V+++ DN F T NKQ S + P ++ +++SE+ K GV F + + E+ + E Sbjct: 167 SSVVMMSDNGFNTLNKQASTIYP-VKDLSKSEQEKVNDISGVKVFTENDITSEIPSYQAE 225 Query: 1460 SLP 1468 P Sbjct: 226 QAP 228
>Q63JL6:TRUA_BURPS tRNA pseudouridine synthase A - Burkholderia pseudomallei| (Pseudomonas pseudomallei) Length = 271 Score = 32.0 bits (71), Expect = 9.2 Identities = 33/132 (25%), Positives = 53/132 (40%), Gaps = 1/132 (0%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFK-AGGILESNYGKLQKVGWERSS 469 R+ L + Y G+ + G Q Q T++ LE ++ + A L + + Sbjct: 3 RIALGIQYDGAAFCGWQSQPH---GKTVQDALERSLAEFAQTSLHTTV----------AG 49 Query: 470 RTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVR 649 RTD GVH L ++ ++ DRA + N+ LP + V P +F R Sbjct: 50 RTDTGVHGLGQVVHFDTDL-DRA------DFSWVRGTNAFLPPTVAVQWAKPMPDTFHAR 102 Query: 650 RECLYREYFYLL 685 R Y+Y L Sbjct: 103 FAAFERTYYYAL 114
>Q62AJ2:TRUA_BURMA tRNA pseudouridine synthase A - Burkholderia mallei (Pseudomonas| mallei) Length = 270 Score = 32.0 bits (71), Expect = 9.2 Identities = 33/132 (25%), Positives = 53/132 (40%), Gaps = 1/132 (0%) Frame = +2 Query: 293 RVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFK-AGGILESNYGKLQKVGWERSS 469 R+ L + Y G+ + G Q Q T++ LE ++ + A L + + Sbjct: 2 RIALGIQYDGAAFCGWQSQPH---GKTVQDALERSLAEFAQTSLHTTV----------AG 48 Query: 470 RTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVR 649 RTD GVH L ++ ++ DRA + N+ LP + V P +F R Sbjct: 49 RTDTGVHGLGQVVHFDTDL-DRA------DFSWVRGTNAFLPPTVAVQWAKPMPDTFHAR 101 Query: 650 RECLYREYFYLL 685 R Y+Y L Sbjct: 102 FAAFERTYYYAL 113
>Q6ANM1:TRUA1_DESPS tRNA pseudouridine synthase A 1 - Desulfotalea psychrophila| Length = 251 Score = 32.0 bits (71), Expect = 9.2 Identities = 29/132 (21%), Positives = 53/132 (40%) Frame = +2 Query: 290 KRVVLRVGYVGSEYRGLQKQRDLSGDSTIESVLESAIFKAGGILESNYGKLQKVGWERSS 469 + + L + + G++Y G QKQ +TI+ +E+ + + ++++ + Sbjct: 2 RNICLLIAFDGTDYSGWQKQHHA---NTIQGEIEARLKRL---------SVKEISLHGAG 49 Query: 470 RTDKGVHSLATMISLKMEIPDRAWEKDPDGIALANFINSNLPDNIKVFSILPAQRSFDVR 649 RTD GVH A ++ R D +N LP I++ + F R Sbjct: 50 RTDAGVH--ADGMTAHFHTDTRLTCND-----FQRALNRMLPGAIRILQVREMADDFHAR 102 Query: 650 RECLYREYFYLL 685 +EY Y L Sbjct: 103 FAATGKEYHYRL 114
>P0AD68:FTSI_ECOLI Peptidoglycan synthetase ftsI precursor - Escherichia coli| Length = 588 Score = 32.0 bits (71), Expect = 9.2 Identities = 36/129 (27%), Positives = 52/129 (40%), Gaps = 14/129 (10%) Frame = +2 Query: 437 KLQKVGWERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGI-------ALANFINSNLP 595 ++Q+V R TD+ LA + +K D D GI ALAN +N L Sbjct: 63 RVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAGGISVGDRWKALANALNIPLD 122 Query: 596 DNIKVFSILPAQRSFDVRRECLYREYFYLLPAEIIGI------KSSCSSGEVEEHLIEFN 757 + P R + R+ Y+ ++ GI + SGEV HLI F Sbjct: 123 QLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIHLREESRRYYPSGEVTAHLIGFT 182 Query: 758 NI-LKGFEG 781 N+ +G EG Sbjct: 183 NVDSQGIEG 191
>P0AD69:FTSI_ECO57 Peptidoglycan synthetase ftsI precursor - Escherichia coli O157:H7| Length = 588 Score = 32.0 bits (71), Expect = 9.2 Identities = 36/129 (27%), Positives = 52/129 (40%), Gaps = 14/129 (10%) Frame = +2 Query: 437 KLQKVGWERSSRTDKGVHSLATMISLKMEIPDRAWEKDPDGI-------ALANFINSNLP 595 ++Q+V R TD+ LA + +K D D GI ALAN +N L Sbjct: 63 RVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAGGISVGDRWKALANALNIPLD 122 Query: 596 DNIKVFSILPAQRSFDVRRECLYREYFYLLPAEIIGI------KSSCSSGEVEEHLIEFN 757 + P R + R+ Y+ ++ GI + SGEV HLI F Sbjct: 123 QLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIHLREESRRYYPSGEVTAHLIGFT 182 Query: 758 NI-LKGFEG 781 N+ +G EG Sbjct: 183 NVDSQGIEG 191
>Q9BXL6:CAR14_HUMAN Caspase recruitment domain-containing protein 14 - Homo sapiens| (Human) Length = 1004 Score = 32.0 bits (71), Expect = 9.2 Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 4/53 (7%) Frame = -2 Query: 1388 LQIH*LTACQDEQYSLACSLCRNC----YL*GSELQRARLVKRCEKTLQVKVL 1242 L +H A Q+++ LA S CR+ YL ELQRA +V CE LQ + L Sbjct: 201 LSLHYSNALQEKE--LAASRCRSLQEELYLLKQELQRANMVSSCELELQEQSL 251 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 328,348,690 Number of extensions: 7180838 Number of successful extensions: 17787 Number of sequences better than 10.0: 178 Number of HSP's gapped: 17682 Number of HSP's successfully gapped: 199 Length of query: 628 Length of database: 100,686,439 Length adjustment: 119 Effective length of query: 509 Effective length of database: 68,045,334 Effective search space: 34635075006 Effective search space used: 34635075006 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
