>Q5RAB8:FARP1_PONPY FERM, RhoGEF and pleckstrin domain-containing protein 1 - Pongo|
           pygmaeus (Orangutan)
          Length = 1045
 Score = 39.3 bits (90), Expect = 0.071
 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
 Frame = +1

Query: 76  EEFEALLDDGEPSDPQPVQKPIDDRYSSPYLSANSKNS--NVKNPKILVNPLVKLDGGIN 249
           EE E + D  + S PQP Q        SP+LS  S NS   V    + ++P        N
Sbjct: 450 EEEEVVKDRTQQSKPQPPQPSTGSLTGSPHLSELSVNSQGGVAPANVTLSP--------N 501

Query: 250 SARDKAQDFELRGPRLSGTLPPLNDAKNENRKKKFFTE 363
            + D  Q   L  P L+    P  D ++E R+K+F T+
Sbjct: 502 LSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRFPTD 539

>Q9Y4F1:FARP1_HUMAN FERM, RhoGEF and pleckstrin domain-containing protein 1 - Homo|
           sapiens (Human)
          Length = 1045

 Score = 39.3 bits (90), Expect = 0.071
 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
 Frame = +1

Query: 76  EEFEALLDDGEPSDPQPVQKPIDDRYSSPYLSANSKNS--NVKNPKILVNPLVKLDGGIN 249
           EE E + D  + S PQP Q        SP+LS  S NS   V    + ++P        N
Sbjct: 450 EEEEVVKDRTQQSKPQPPQPSTGSLTGSPHLSELSVNSQGGVAPANVTLSP--------N 501

Query: 250 SARDKAQDFELRGPRLSGTLPPLNDAKNENRKKKFFTE 363
            + D  Q   L  P L+    P  D ++E R+K+F T+
Sbjct: 502 LSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRFPTD 539

>Q4WI96:KU80_ASPFU Protein Ku80 - Aspergillus fumigatus (Sartorya fumigata)|
          Length = 725

 Score = 38.9 bits (89), Expect = 0.093
 Identities = 29/127 (22%), Positives = 53/127 (41%), Gaps = 1/127 (0%)
 Frame = +1

Query: 448 NKNVPKLGVPPESLRETNKAMQKNSYNELVTLFKDSTSQNPTRVFDENPVPSARPIATRR 627
           +KN+ KL  PP+ L E +KA  +                   ++ +   V    P    R
Sbjct: 524 SKNLTKLSQPPQDLVEKSKAYLQ-------------------KLMEAADVKKVPPKVKGR 564

Query: 628 SSLEFKESPVIKTPIEALLTPHSEQKRSPKN-LKDPMQALREAEAIKNAKKTIEDLVAAI 804
             +   E P+    ++ALL      + SP N + +  Q L +AE I+  K  ++ + + I
Sbjct: 565 KRIRESEKPLSGLDVDALLHQEKRARISPTNAIPEFKQTLTQAETIETIKDAVKQMTSII 624

Query: 805 QCETSNN 825
           + +  N+
Sbjct: 625 EDQIKNS 631

>O67109:Y983_AQUAE Uncharacterized protein aq_983 - Aquifex aeolicus|
          Length = 292

 Score = 38.1 bits (87), Expect = 0.16
 Identities = 38/176 (21%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
 Frame = +1

Query: 919  VVIDIVNFGVQDRTELALRAGFFQDIGNTVNLMAKAISGQENEGKHILIYLHNRLDQRKL 1098
            VV+ +  + + D   L   A + Q     ++L+A  +        + + YL  ++     
Sbjct: 3    VVLSLETWDIDDTLALLFLAHYHQK--GKIDLLAVEVDKGPPSQNNYVKYLLQKIHLNVP 60

Query: 1099 FFSKFFFIVKNNNNYPIGLKSEKEIIMNYLITLGILQFKLKFEDKPVSEDKINFVKNKAL 1278
             FS+              ++ +K  +  Y   L     KL+ ++    E+ ++ +K K  
Sbjct: 61   VFSR-------------NVEEDKSELPEYYYEL-FEDLKLESQESQRREELLDLLKGKEF 106

Query: 1279 NLMKGTDNSISPFLCDWLNYRVRQQIFVEKFYINQNIKGKTDHNF-------TYNF 1425
             L+ G   ++ PFL +  N    ++IFV+  +  +NI GKT   F       T+NF
Sbjct: 107  KLVVGGSLNLIPFLLE--NSVFPEEIFVQGGFAGKNITGKTHEKFGDRYFKATFNF 160

>Q02952:AKA12_HUMAN A-kinase anchor protein 12 - Homo sapiens (Human)|
          Length = 1781

 Score = 37.0 bits (84), Expect = 0.35
 Identities = 58/309 (18%), Positives = 120/309 (38%), Gaps = 38/309 (12%)
 Frame = +1

Query: 106 EPSDPQPVQKPIDDRYSSPYLSANSKNSNVKNPKILVNPLVKLDGGINSARDKAQDFELR 285
           EPS   P  +   D  + P ++A+   + +         L  ++G         Q+ +L 
Sbjct: 26  EPSGGGPSAEAAPDTTADPAIAASDPATKLLQKN---GQLSTINGVAEQDELSLQEGDLN 82

Query: 286 GPRLSGTLPPLNDAKNENRKKKFFTELHKPNNEKLSNR-----MIPNIVFTH--ANEGKE 444
           G +  G L       ++  ++   TE+ + ++E +S R     M       H   ++G+E
Sbjct: 83  GQK--GALNGQGALNSQEEEEVIVTEVGQRDSEDVSERDSDKEMATKSAVVHDITDDGQE 140

Query: 445 ENKNVPKLGVPPESLRETNKAMQKNSYN---------------------------ELVTL 543
           EN+N+ ++     +L E  +  +  + +                           +L+T+
Sbjct: 141 ENRNIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEKPDTVQLLTV 200

Query: 544 FKDSTSQNPTRVFDENPVPSARPIATRRS----SLEFKESPVIKTPIEALLTPHSEQKRS 711
            KD           ++P   A   A++ S    S E  E  + +    A ++P +E  ++
Sbjct: 201 KKDEGEGAAGAGDHQDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQA 260

Query: 712 PKNLKDPMQALREAEAIKNAKKTIEDLVAAIQCETSNNYSQSPKFESQKLDVNNWRELTQ 891
            +  K+  +  +E E  K+A    E   + +  ET + +    KF +Q      WR+ T 
Sbjct: 261 VEECKEEGEEKQEKEPSKSA----ESPTSPVTSETGSTFK---KFFTQ--GWAGWRKKTS 311

Query: 892 YLQPSKVEI 918
           + +P + E+
Sbjct: 312 FRKPKEDEV 320

>P38742:YHC3_YEAST Uncharacterized protein YHL023C - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 1146

 Score = 35.8 bits (81), Expect = 0.78
 Identities = 45/200 (22%), Positives = 75/200 (37%), Gaps = 17/200 (8%)
 Frame = +1

Query: 1429 DYLTSISSRFLTAPSKGSPREKLSPNQSSPRLMAKSAFSATSSPFKR--DRESTKHFTIL 1602
            DYL   S  F  + S  S     SP+ SS     +   S T+S F+       T    I+
Sbjct: 164  DYLDISSDSFSISSSLSSSSLSSSPSSSSSSSPPQDGLSRTNSSFQSTDSMSPTSPQMIM 223

Query: 1603 ASDPINFPDNFIPPSTASKKNKASPSPLLF------ENNSDIQRH---------PTLITA 1737
             +D I+  ++++   T +K   AS     F      + ++D + H         P+  T 
Sbjct: 224  ENDSISVAESYLDSGTNNKSRAASKRSQNFFHKLSTKKSTDSKTHSPVRKLKSKPSQSTK 283

Query: 1738 RNNGFVPILNMSNVTKPMTSLNYLSPRERNHTMMTSKEIKSAKKFYQVVDNTEFFDLGIR 1917
            + N    + N SN T         S       + + K + S  +  Q + N+   D   +
Sbjct: 284  KGNKL--LKNTSNETDGNAFTGSCS-------ISSKKSLSSTGEHNQELRNSSLNDTPGQ 334

Query: 1918 KPKLPFHNLNSYFKNIISSE 1977
             P    H  + Y KN  +S+
Sbjct: 335  SPHHYHHRYHHYHKNAATSQ 354

>Q8KA07:SYGB_BUCAP Glycyl-tRNA synthetase beta chain - Buchnera aphidicola subsp.|
            Schizaphis graminum
          Length = 691

 Score = 35.4 bits (80), Expect = 1.0
 Identities = 47/202 (23%), Positives = 87/202 (43%), Gaps = 10/202 (4%)
 Frame = +1

Query: 877  RELTQYLQPSKVEIVV--IDIVNFGVQDRTELALRAGFFQDIGNTVNLMAKAISGQE--N 1044
            +E  + L P  +E ++  I++ N    + T L     F + I N V L+ + I   E  N
Sbjct: 124  KEKIELLFPKIIEKILKQINLKNTMRWETTNLR----FIRPIRNIVMLLDEKIIKSEVFN 179

Query: 1045 EGKHILIYLHNRLDQRKLFFSKFFFIVKNNNNYPIGLKSEKEIIMNYLITLGILQFKLKF 1224
               +  +Y H    + K++       +KN   YP  L  + +II NY       + K+K+
Sbjct: 180  VPSNNFLYHHISCKEEKIY-------IKNAIEYPAVLFKKNKIIANY----ETRKEKIKY 228

Query: 1225 EDKPVSED-----KIN-FVKNKALNLMKGTDNSISPFLCDWLNYRVRQQIFVEKFYINQN 1386
            E K +++      K N F+  +  +L++     ++ F  D++NY + ++I +      Q 
Sbjct: 229  EAKKIAKKVDGIIKTNPFLLEEVTSLVESPQALLARFKKDYINY-IPKKILIHTIEKQQR 287

Query: 1387 IKGKTDHNFTYNFLDYLTSISS 1452
                  +N     L Y   IS+
Sbjct: 288  CFSIYSNNSKKEILPYFIFISN 309

>Q3UMY5:EMAL4_MOUSE Echinoderm microtubule-associated protein-like 4 - Mus musculus|
           (Mouse)
          Length = 988

 Score = 35.4 bits (80), Expect = 1.0
 Identities = 34/143 (23%), Positives = 62/143 (43%), Gaps = 21/143 (14%)
 Frame = +1

Query: 553 STSQNPTRVFDENPVPSARPIATRRSSLEFKESPVIKTPIEALLTPHSEQK--RSPKNLK 726
           S  Q+P      +P PS++P+   R + E K S     PI+++  P + +K   S +N  
Sbjct: 134 SNDQSPQIRASPSPQPSSQPLQINRQTPESKSS----APIKSIKRPPTAEKSHNSWENSD 189

Query: 727 DPMQALRE--------AEAIKNAKKTIEDLVAAIQCETSNNYSQSPKFESQKL------- 861
           D    L +        ++ IKNA K  + +V   +  T    SQ  ++    +       
Sbjct: 190 DSRNKLMKTVSTSKLISKVIKNADKHKDVIVNQAKMSTREKNSQEGEYIKMFMRGRPITM 249

Query: 862 ----DVNNWRELTQYLQPSKVEI 918
               DV+N+ ++   L P K+++
Sbjct: 250 FIPSDVDNYDDIRTELPPEKLKL 272

>Q6GP17:SU41A_XENLA Histone-lysine N-methyltransferase SUV420H1-A - Xenopus laevis|
           (African clawed frog)
          Length = 855

 Score = 34.7 bits (78), Expect = 1.7
 Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 12/131 (9%)
 Frame = +1

Query: 487 LRETNKAMQKNSYNELVTLFKDSTSQNPTRVFDENPVPSARPIATRRS--------SLEF 642
           LRET+K +  N   +L    K+S SQ+ +   D +     + ++ R+S        S   
Sbjct: 327 LRETDKRL--NRLKKLGDSGKNSDSQSVSSNTDAD-TSQEKDMSNRKSNGMRKRSKSRTL 383

Query: 643 KESPVIKTPIEALLT----PHSEQKRSPKNLKDPMQALREAEAIKNAKKTIEDLVAAIQC 810
           +   + + P+ +  T    PH    R PK L+ P +       I+  +K +E   A+ + 
Sbjct: 384 RRRSMSRIPVSSSSTSSKLPHINNSRVPKRLRKPPKPFHSKLKIRCHRKKVEQKKASKKL 443

Query: 811 ETSNNYSQSPK 843
           E SN   + PK
Sbjct: 444 EVSNLVLKEPK 454

>Q9R1N3:S4A7_RAT Sodium bicarbonate cotransporter 3 - Rattus norvegicus (Rat)|
          Length = 1218

 Score = 34.7 bits (78), Expect = 1.7
 Identities = 46/198 (23%), Positives = 88/198 (44%), Gaps = 7/198 (3%)
 Frame = +1

Query: 145 DRYSSPYLSANSKNSNVKNPKILVNPLVKLDGGINSARDKAQDFELRGPRLSGTLPPLND 324
           DR+S PY++  S +S  +    ++N  V LD    S  D+  D  L     SG    L+D
Sbjct: 152 DRWSKPYVATLSLHSLFELRSCILNGTVMLDMRA-STLDEIADMVLDNMIASG---QLDD 207

Query: 325 AKNENRKKKFFTELHKPNNEKLSNRMIPNIVFTHANEGKEENKNVPKLGVPPESLRETNK 504
           +  EN ++      H  N ++ ++R IP +V + A+ GK+ +         P  L    +
Sbjct: 208 SIRENVREALLKRHHHQNEKRFTSR-IP-LVRSFADIGKKHS--------DPHLLERNGE 257

Query: 505 AMQKNSYNELVTLFKDSTS---QNPTRVFDENPVPSAR---PIATR-RSSLEFKESPVIK 663
            +  + ++    L   + S   ++P  +   + +PS+R   P  +R  + +   ++    
Sbjct: 258 GLSASRHSLRTGLSASNLSLRGESPLSLLLSHLLPSSRAGTPAGSRCTTPVPTPQNSPPS 317

Query: 664 TPIEALLTPHSEQKRSPK 717
           +P  + LT  S Q+  P+
Sbjct: 318 SPSLSRLTSRSSQQTQPQ 335

>O25722:FTSK_HELPY DNA translocase ftsK - Helicobacter pylori (Campylobacter pylori)|
          Length = 858

 Score = 34.7 bits (78), Expect = 1.7
 Identities = 38/181 (20%), Positives = 63/181 (34%), Gaps = 5/181 (2%)
 Frame = +1

Query: 319 NDAKNENRKKKFFTELHKPNNEKLSNRMIPNIVFTHANEGKEENKNVPKLGVPPESLRET 498
           ND + ENRK+    E HK  NE+     IP    T  N+ + +   V     PP      
Sbjct: 193 NDKEKENRKENPINENHKTPNEE-PFLAIPTPYNTTLNDSEPQEGLVQISSHPPTHYTIY 251

Query: 499 NKAMQKNSYNELVTLFKDSTSQNPTRVFDENPVPSARPIATRRSSLEFKESPVIKTPIEA 678
            K   +N +++L         +      +  P P+   +           +P    PI  
Sbjct: 252 PK---RNRFDDLTNPTNPPLKEIKQETKEREPTPTKETL-----------TPTTPKPIMP 297

Query: 679 LLTPHSEQKRSPKNLKDPMQALREAEAIKNAKK-----TIEDLVAAIQCETSNNYSQSPK 843
            L P  E     +N K P    +E    +N ++      IE+++     +       +P 
Sbjct: 298 TLAPIIENDNKTENQKTPNHPKKEENPQENTQEEMIEGRIEEMIKENLKKEEKEVQNAPN 357

Query: 844 F 846
           F
Sbjct: 358 F 358

>Q6PH08:ERC2_MOUSE ERC protein 2 - Mus musculus (Mouse)|
          Length = 957

 Score = 34.7 bits (78), Expect = 1.7
 Identities = 54/214 (25%), Positives = 93/214 (43%), Gaps = 6/214 (2%)
 Frame = +1

Query: 175  NSKNSNVKNPKILVNPLVKLDGGINSARDKAQDFELRGPRLSGTLPPLNDAKNENRKKKF 354
            N ++ +  NP+   + L +LD   +  RD+    +    RL   L  + + KN+  KK  
Sbjct: 690  NIEDDSRMNPEF-ADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIA 748

Query: 355  FTELHKPNNEKLSNRMIPNIVFTHANEGKEENKNVPKLGVPPESLRETNKAMQKNSYNEL 534
              E     + K  N+ + N+ +   N+  E+ KN   L    E +R    +M  NS +  
Sbjct: 749  ELESLTLRHMKDQNKKVANLKY---NQQLEKKKNAQLL----EEVRRREDSMVDNSQHLQ 801

Query: 535  VTLFKDSTSQNPTRVFDENPVPSARPIATRRSSLEFKESPVI------KTPIEALLTPHS 696
            +    ++  +  TR   E     AR +A+ + SL  KE+ +       +  +E +L    
Sbjct: 802  IEELMNALEK--TR--QELDATKAR-LASTQQSLAEKEAHLANLRIERRKQLEEILEMKQ 856

Query: 697  EQKRSPKNLKDPMQALREAEAIKNAKKTIEDLVA 798
            E   +  + KD   AL E  A K  KKT E+++A
Sbjct: 857  EALLAAISEKDANIALLELSASKK-KKTQEEVMA 889

>Q9Y6M7:S4A7_HUMAN Sodium bicarbonate cotransporter 3 - Homo sapiens (Human)|
          Length = 1214

 Score = 33.9 bits (76), Expect = 3.0
 Identities = 56/237 (23%), Positives = 103/237 (43%), Gaps = 10/237 (4%)
 Frame = +1

Query: 145 DRYSSPYLSANSKNSNVKNPKILVNPLVKLDGGINSARDKAQDFELRGPRLSGTLPPLND 324
           DR+S PY++  S +S  +    ++N  V LD    S  D+  D  L     SG    L++
Sbjct: 147 DRWSKPYVATLSLHSLFELRSCILNGTVMLDMRA-STLDEIADMVLDNMIASG---QLDE 202

Query: 325 AKNENRKKKFFTELHKPNNEKLSNRMIPNIVFTHANEGKEENKNVPKLGVPPESLRETNK 504
           +  EN ++      H  N ++ ++R IP +V + A+ GK+ +         P  L    +
Sbjct: 203 SIRENVREALLKRHHHQNEKRFTSR-IP-LVRSFADIGKKHS--------DPHLLERNGE 252

Query: 505 AMQKNSYNELVTLFKDSTS---QNPTRVFDENPVPSAR---PIATR-RSSLEFKESPVIK 663
            +  + ++    L   + S   ++P  +   + +PS+R   P  +R  + +   ++    
Sbjct: 253 GLSASRHSLRTGLSASNLSLRGESPLSLLLGHLLPSSRAGTPAGSRCTTPVPTPQNSPPS 312

Query: 664 TPIEALLTPHSEQK---RSPKNLKDPMQALREAEAIKNAKKTIEDLVAAIQCETSNN 825
           +P  + LT  S QK   ++P+ L  P         I   +   EDL AA++ E   N
Sbjct: 313 SPSISRLTSRSSQKSQRQAPELLVSPASDDIPTVVIHPPE---EDLEAALKGEEQKN 366

>Q6NRS1:IBTK_XENLA Inhibitor of Bruton tyrosine kinase - Xenopus laevis (African clawed|
            frog)
          Length = 1339

 Score = 33.9 bits (76), Expect = 3.0
 Identities = 53/214 (24%), Positives = 82/214 (38%), Gaps = 32/214 (14%)
 Frame = +1

Query: 1324 DWLNYRVRQQIFVEKFYINQNIKGKT--DHNFTYNFLDYLTSISSRFLTAPSKGSPREKL 1497
            D  +Y++ Q+  ++K       K +   D +  YN  D + S +S     P K +  E L
Sbjct: 955  DIYSYQITQEATLKKSKAKPKKKQRKRLDSSGGYNLSDIIQSPTSTGFVKPEKTNSVESL 1014

Query: 1498 SP-----------NQSSPR-LMAKSAF---------------SATSSPFKRDRESTKHFT 1596
                           SSPR L +   F               + +S P      STK   
Sbjct: 1015 QDLLTSDSEGSFVGASSPRDLQSPDLFPVFTHETKETICVERNRSSPPVANGAASTKMPI 1074

Query: 1597 ILASDPINFPDNFIPPSTASK--KNKASP-SPLLFENNSDIQRHPTLITARNNGFVPILN 1767
               S P   P + I PST+        SP SP+  +  + ++    +   +  G +P LN
Sbjct: 1075 PTTSSPKAIPMSRITPSTSPNWVAMPCSPASPVTMDLRAIMELEENI---QKCGAMPKLN 1131

Query: 1768 MSNVTKPMTSLNYLSPRERNHTMMTSKEIKSAKK 1869
                TKP T +  LS ++R    M+SKE  +  K
Sbjct: 1132 AGG-TKPGTHVMKLSQKQRKMMAMSSKESNNENK 1164

>P14922:CYC8_YEAST Glucose repression mediator protein CYC8 - Saccharomyces cerevisiae|
            (Baker's yeast)
          Length = 966

 Score = 33.9 bits (76), Expect = 3.0
 Identities = 45/224 (20%), Positives = 84/224 (37%), Gaps = 14/224 (6%)
 Frame = +1

Query: 169  SANSKNSNVKNPKILVN--PLVKLDGGINSARDKAQDFELRGPRLSGTLPPLNDAKNENR 342
            S+    +N K+P+   +  P      GI +A  + +  +L  P             N N+
Sbjct: 700  SSTHTENNTKSPRQPTHAIPTQAPATGITNAEPQVKKQKLNSPN-----------SNINK 748

Query: 343  KKKFFTELHKPNNEKLSNRMIPNIVFTHANEGKEENKNVPKLGVPP-----------ESL 489
                 T + +    ++SN+  P +V ++ N   +E K V    +P               
Sbjct: 749  LVNTATSIEENAKSEVSNQS-PAVVESNTNNTSQEEKPVKANSIPSVIGAQEPPQEASPA 807

Query: 490  RETNKAMQKNSYNELVTLFKDSTSQNPTRVFDENPVPSARPIATRRS-SLEFKESPVIKT 666
             E  KA   +   + +    +S+S  PT V  E+    A   +T  +  L     P   +
Sbjct: 808  EEATKAASVSPSTKPLNTEPESSSVQPT-VSSESSTTKANDQSTAETIELSTATVPAEAS 866

Query: 667  PIEALLTPHSEQKRSPKNLKDPMQALREAEAIKNAKKTIEDLVA 798
            P+E  +  HS+++        P     E  A ++A+K  ++  A
Sbjct: 867  PVEDEVRQHSKEENGTTEASAPSTEEAEPAASRDAEKQQDETAA 910

>P16154:TOXA_CLODI Toxin A - Clostridium difficile|
          Length = 2710

 Score = 33.5 bits (75), Expect = 3.9
 Identities = 55/213 (25%), Positives = 93/213 (43%), Gaps = 13/213 (6%)
 Frame = +1

Query: 1066 YLHNRLDQRKLFFSKFFFIVKNNNNYPIGLKSEKEIIMNYLITLGI--LQFKLKFEDKPV 1239
            Y++N   +    F K    +K+N    I  KSEK  I + L  L +  L+ K+ F     
Sbjct: 325  YINNYTSEN---FDKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAF----- 376

Query: 1240 SEDKINFVKNKALNLMKGTDNSISPFLCDWLNYRVRQQIFVEKFYINQNIKG--KTDHNF 1413
                +  V N+AL   +G+          +L   V +Q+     ++NQ++    ++D+NF
Sbjct: 377  ---ALGSVINQALISKQGS----------YLTNLVIEQVKNRYQFLNQHLNPAIESDNNF 423

Query: 1414 TYN---FLDYL----TSISSRFLTAPSKGSPREKLSPNQSSPRLMAKSAFSATSSPFKRD 1572
            T     F D L    T+ +S FLT  +       +   +S+  L    A+++    F   
Sbjct: 424  TDTTKIFHDSLFNSATAENSMFLTKIAPYLQVGFMPEARSTISLSGPGAYASAYYDFINL 483

Query: 1573 RESTKHFTILASDPI--NFPDNFIPPSTASKKN 1665
            +E+T   T+ ASD I   FP+N +   T  + N
Sbjct: 484  QENTIEKTLKASDLIEFKFPENNLSQLTEQEIN 516

>P40339:RFC4_YEAST Replication factor C subunit 4 - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 323

 Score = 33.5 bits (75), Expect = 3.9
 Identities = 18/67 (26%), Positives = 31/67 (46%)
 Frame = -1

Query: 1137 VIVLDNEEEFTEKQFSLVKSVMEIYQNMLSFIFLS*NSFCHQINSIPNILKESCSEGKFS 958
            +++LD  +  T      ++  ME+Y N   F F      C+Q N I   L+  C+  ++S
Sbjct: 110  IVILDEADSMTAGAQQALRRTMELYSNSTRFAFA-----CNQSNKIIEPLQSRCAILRYS 164

Query: 957  PILDTKV 937
             + D  V
Sbjct: 165  KLSDEDV 171

>Q9BL02:CUT_CAEEL Homeobox protein cut-like ceh-44 - Caenorhabditis elegans|
          Length = 1273

 Score = 33.5 bits (75), Expect = 3.9
 Identities = 35/158 (22%), Positives = 74/158 (46%), Gaps = 23/158 (14%)
 Frame = +1

Query: 559  SQNPTRVF--DEN-PVPSARPIATRRSSLEFKESPVIKTPIEALLTPHSEQKRSPKNLKD 729
            S +P RV+  D+N   P A  +      +EFKE PVI+  +   + P  E+ +SP  ++ 
Sbjct: 677  SLSPRRVWPADQNIEHPKAETLLDTSDPMEFKEEPVIRYDVTPKVEPVIEKIKSP--VES 734

Query: 730  PMQALREAEAIKNAKKTIED-----LVAAIQCETSNNYSQSPKFE------------SQK 858
            P  +   A +++ ++   +D     +++ +Q E      ++ + +            +++
Sbjct: 735  PCSSQAGASSLRASRWRHDDISKEKILSILQTELKKIEEETTESKVVVPVKPTATGGNRR 794

Query: 859  LDVNNWRE---LTQYLQPSKVEIVVIDIVNFGVQDRTE 963
               N+  E   LT   +PS VE+++   ++ G+Q  T+
Sbjct: 795  FSSNSTYESSSLTGKSRPSTVELILKQRISTGLQPLTQ 832

>P12036:NFH_HUMAN Neurofilament heavy polypeptide - Homo sapiens (Human)|
          Length = 1026

 Score = 33.1 bits (74), Expect = 5.1
 Identities = 50/243 (20%), Positives = 90/243 (37%), Gaps = 3/243 (1%)
 Frame = +1

Query: 67   TELEEFEALLDDG---EPSDPQPVQKPIDDRYSSPYLSANSKNSNVKNPKILVNPLVKLD 237
            TE EE EA  ++G   E  + +  +   ++  S P   A S     K+P       VK +
Sbjct: 471  TEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP-------VKEE 523

Query: 238  GGINSARDKAQDFELRGPRLSGTLPPLNDAKNENRKKKFFTELHKPNNEKLSNRMIPNIV 417
                +     +  E + P    +         E  K     E   P  E+  +       
Sbjct: 524  AKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP--PEAKSPEKEEAKSPAEVKSP 581

Query: 418  FTHANEGKEENKNVPKLGVPPESLRETNKAMQKNSYNELVTLFKDSTSQNPTRVFDENPV 597
                +  KEE K+ P     PE  +   K   K+           + +++P +   ++P 
Sbjct: 582  EKAKSPAKEEAKS-PAEAKSPEKAKSPVKEEAKSP----------AEAKSPVKEEAKSPA 630

Query: 598  PSARPIATRRSSLEFKESPVIKTPIEALLTPHSEQKRSPKNLKDPMQALREAEAIKNAKK 777
                P   +  + E  +SP      E   +P  E+ +SP+  K P++A  EA++ + AK 
Sbjct: 631  EVKSPEKAKSPTKEEAKSPEEAKSPEKAKSPEKEEAKSPEKAKSPVKA--EAKSPEKAKS 688

Query: 778  TIE 786
             ++
Sbjct: 689  PVK 691

>O15083:ERC2_HUMAN ERC protein 2 - Homo sapiens (Human)|
          Length = 957

 Score = 33.1 bits (74), Expect = 5.1
 Identities = 53/214 (24%), Positives = 92/214 (42%), Gaps = 6/214 (2%)
 Frame = +1

Query: 175  NSKNSNVKNPKILVNPLVKLDGGINSARDKAQDFELRGPRLSGTLPPLNDAKNENRKKKF 354
            N ++ +  NP+   + + +LD   +  RD+    +    RL   L  + + KN+  KK  
Sbjct: 690  NIEDDSRMNPEF-ADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIA 748

Query: 355  FTELHKPNNEKLSNRMIPNIVFTHANEGKEENKNVPKLGVPPESLRETNKAMQKNSYNEL 534
              E     + K  N+ + N+     N+  E+ KN   L    E +R    +M  NS +  
Sbjct: 749  ELESLTLRHMKDQNKKVANL---KHNQQLEKKKNAQLL----EEVRRREDSMADNSQHLQ 801

Query: 535  VTLFKDSTSQNPTRVFDENPVPSARPIATRRSSLEFKESPVI------KTPIEALLTPHS 696
            +    ++  +  TR   E     AR +A+ + SL  KE+ +       +  +E +L    
Sbjct: 802  IEELMNALEK--TR--QELDATKAR-LASTQQSLAEKEAHLANLRIERRKQLEEILEMKQ 856

Query: 697  EQKRSPKNLKDPMQALREAEAIKNAKKTIEDLVA 798
            E   +  + KD   AL E  A K  KKT E+++A
Sbjct: 857  EALLAAISEKDANIALLELSASKK-KKTQEEVMA 889

>P53316:YG5B_YEAST Uncharacterized RNA-binding protein YGR250C - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 781

 Score = 32.7 bits (73), Expect = 6.6
 Identities = 21/72 (29%), Positives = 33/72 (45%)
 Frame = +1

Query: 1624 PDNFIPPSTASKKNKASPSPLLFENNSDIQRHPTLITARNNGFVPILNMSNVTKPMTSLN 1803
            P N    +  +K NK   + L+ +N S  Q       +R N F+P+   +  TKP+ S N
Sbjct: 664  PHNDYHKAYPTKYNKKFINALMTQNQSQQQ------VSRENYFIPLQYPNTNTKPVNSYN 717

Query: 1804 YLSPRERNHTMM 1839
             +S  + N   M
Sbjct: 718  LISANQNNANWM 729

>P48994:TRPL_DROME Transient-receptor-potential-like protein - Drosophila melanogaster|
            (Fruit fly)
          Length = 1124

 Score = 32.7 bits (73), Expect = 6.6
 Identities = 19/44 (43%), Positives = 27/44 (61%)
 Frame = +1

Query: 1159 SEKEIIMNYLITLGILQFKLKFEDKPVSEDKINFVKNKALNLMK 1290
            SE + IM  L+   +     KFE+ PVSED IN VK++ +N M+
Sbjct: 740  SEYDNIMRSLVWRYVAAMHRKFENNPVSEDDINEVKSE-INTMR 782

>Q5EAW9:TAF3_XENLA Transcription initiation factor TFIID subunit 3 - Xenopus laevis|
           (African clawed frog)
          Length = 845

 Score = 32.7 bits (73), Expect = 6.6
 Identities = 34/139 (24%), Positives = 55/139 (39%), Gaps = 4/139 (2%)
 Frame = +1

Query: 373 PNNEKLSNRMIPNIVFTHANEGKEENKNVPKLGVPPESLRETNKAMQKNSYNELVTLFKD 552
           P    +S    P +  +  N GK  + +VP  G    S  + +  M  +S NE++   + 
Sbjct: 351 PKRLNISELTTPKVSASGINPGKTSSTSVPASGGTSSS--DISWTMD-DSINEVI---RK 404

Query: 553 STSQNPTRVFDENPV----PSARPIATRRSSLEFKESPVIKTPIEALLTPHSEQKRSPKN 720
            + + PT     NP     PSA P         F++   +  P+E       EQ+   K 
Sbjct: 405 VSQETPTNTPANNPPCFSSPSASPPTPEPLLKVFEDKAKLPPPVELKKKTKKEQRAKKKK 464

Query: 721 LKDPMQALREAEAIKNAKK 777
            KD    L++ E  K+  K
Sbjct: 465 DKD---KLKDKERSKDKNK 480

>Q02455:MLP1_YEAST Protein MLP1 - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 1875

 Score = 32.7 bits (73), Expect = 6.6
 Identities = 83/391 (21%), Positives = 157/391 (40%), Gaps = 59/391 (15%)
 Frame = +1

Query: 175  NSKNSNVKNPKILVNPLVKLDGGINSARDKAQDF--ELRGPRLSGTLPPLNDAKNENRKK 348
            +++N ++ N +I      K D  I   ++K+     E R   LS TL  L  A+N+  +K
Sbjct: 654  STENMSLLNKEIQDLYDSKSDISIKLGKEKSSRILAEERFKLLSNTLD-LTKAENDQLRK 712

Query: 349  KFF----------TELHKPNNEKLSNRMIPNIVFTHANEGKEENK-----------NVPK 465
            +F           ++ H+  NE +S +   +IV T     KEE K            + K
Sbjct: 713  RFDYLQNTILKQDSKTHETLNEYVSCKSKLSIVETELLNLKEEQKLRVHLEKNLKQELNK 772

Query: 466  LGVPPESLR------------------ETNKAMQK--NSYNELVTLFKDSTSQNPTRV-- 579
            L    +SLR                  ET K+ QK  +   + ++  K  TSQ    +  
Sbjct: 773  LSPEKDSLRIMVTQLQTLQKEREDLLEETRKSCQKKIDELEDALSELKKETSQKDHHIKQ 832

Query: 580  FDENPVPSARPIATRRSSLEFKESPV--IKTPIEALLTPHSEQKRSPKNLKDPMQAL-RE 750
             +E+            S++E+ ++ +  +K   E+++T    ++   + L+  +++L +E
Sbjct: 833  LEED----------NNSNIEWYQNKIEALKKDYESVITSVDSKQTDIEKLQYKVKSLEKE 882

Query: 751  AEAIKNAKKTIEDLVAAIQCETSNNYSQSPKFESQKLDVNN-WRELTQYLQPSKVEIVVI 927
             E  K    T       +  ET N+ S   + E  K+++ + + ++ +Y    +     +
Sbjct: 883  IEEDKIRLHTYN-----VMDETINDDSLRKELEKSKINLTDAYSQIKEYKDLYETTSQSL 937

Query: 928  DIVNFGVQDRTELALRAGFFQDIGNTVNLMAKAISGQENEG---KHILIYLHNRLD---- 1086
               N  + +          F+D  N +  +    +  E++    K  +  L+N LD    
Sbjct: 938  QQTNSKLDES---------FKDFTNQIKNLTDEKTSLEDKISLLKEQMFNLNNELDLQKK 988

Query: 1087 ---QRKLFFSKFFFIVKNNNNYPIGLKSEKE 1170
               + K  F K   I++NNN     +KSE E
Sbjct: 989  GMEKEKADFKKRISILQNNNKEVEAVKSEYE 1019

>P46821:MAP1B_HUMAN Microtubule-associated protein 1B - Homo sapiens (Human)|
          Length = 2468

 Score = 32.7 bits (73), Expect = 6.6
 Identities = 63/299 (21%), Positives = 111/299 (37%)
 Frame = +1

Query: 25   SQLKLMLTPSELLKTELEEFEALLDDGEPSDPQPVQKPIDDRYSSPYLSANSKNSNVKNP 204
            S+ K+M+   + +KTE +      +     +P PV+  + ++ ++      +K   VK  
Sbjct: 582  SKEKVMVKKDKPVKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKK- 640

Query: 205  KILVNPLVKLDGGINSARDKAQDFELRGPRLSGTLPPLNDAKNENRKKKFFTELHKPNNE 384
            +  V P            DK ++ E          P    AK E+  K    +  KP  E
Sbjct: 641  ETKVKP-----------EDKKEEKE---------KPKKEVAKKED--KTPIKKEEKPKKE 678

Query: 385  KLSNRMIPNIVFTHANEGKEENKNVPKLGVPPESLRETNKAMQKNSYNELVTLFKDSTSQ 564
            ++   +   I      E KE  K V K   P E  +E  K  +K    E     K+    
Sbjct: 679  EVKKEVKKEI---KKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKL 735

Query: 565  NPTRVFDENPVPSARPIATRRSSLEFKESPVIKTPIEALLTPHSEQKRSPKNLKDPMQAL 744
                     P+  A+  A  +  +  KE  V K  + A      ++K   K +K   +A 
Sbjct: 736  PKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAA---GKPKEKGKIKVIKKEGKA- 791

Query: 745  REAEAIKNAKKTIEDLVAAIQCETSNNYSQSPKFESQKLDVNNWRELTQYLQPSKVEIV 921
              AEA+  A  T     A +          + + E+++  +++  +LT+  +  K E V
Sbjct: 792  --AEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEV 848

>Q86V48:LUZP1_HUMAN Leucine zipper protein 1 - Homo sapiens (Human)|
          Length = 1076

 Score = 32.7 bits (73), Expect = 6.6
 Identities = 42/201 (20%), Positives = 81/201 (40%), Gaps = 27/201 (13%)
 Frame = +1

Query: 1   EKLKYYSCSQLKLMLTPSELLKTELEEFEALLDDGEPSDPQPVQKPIDDRYSSPYLSANS 180
           EK +    +++K +    E LKT+++ FE+L ++ +        K  ++     YLS  +
Sbjct: 278 EKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKK------MKSKNNDLQDNYLSEQN 331

Query: 181 KN----SNVKNPKILVNPLVKLDGG---------INSARDKAQDFELRGPRLSGTLPPLN 321
           KN    S ++  K+ +    +L+ G          +  R +   F   G   S +     
Sbjct: 332 KNKLLASQLEEIKLQIKKQKELENGEVEGEDAFLSSKGRHERTKFRGHGSEASVSKHTAR 391

Query: 322 DAKNENRKKKFFTELHKPNNE--KLSNRMIPNIVFTH------------ANEGKEENKNV 459
           +   ++++++        NNE   LSNR + +  FT+             + G +E K  
Sbjct: 392 ELSPQHKRERLRNREFALNNENYSLSNRQVSSPSFTNRRAAKASHMGVSTDSGTQETKKT 451

Query: 460 PKLGVPPESLRETNKAMQKNS 522
               VP  S  E  K+ ++ S
Sbjct: 452 EDRFVPGSSQSEGKKSREQPS 472

>O13297:CET1_YEAST mRNA-capping enzyme subunit beta - Saccharomyces cerevisiae|
           (Baker's yeast)
          Length = 549

 Score = 32.7 bits (73), Expect = 6.6
 Identities = 32/152 (21%), Positives = 56/152 (36%), Gaps = 12/152 (7%)
 Frame = +1

Query: 295 LSGTLPPLNDAKNENRKKKFFTELHKPNNEKLSNRMIPNIVFTHANEGKEENKNVPKLG- 471
           LS   PP+ND  + N K      L KP+++ +           H N   +E + +PK G 
Sbjct: 120 LSNGSPPMNDGSDANAK------LEKPSDDSI-----------HQNSKSDEEQRIPKQGN 162

Query: 472 -----------VPPESLRETNKAMQKNSYNELVTLFKDSTSQNPTRVFDENPVPSARPIA 618
                      VP +  ++T K +  N+   +V   ++  +     +F+E     ++   
Sbjct: 163 EGNIASNYITQVPLQKQKQTEKKIAGNAVGSVVKK-EEEANAAVDNIFEEKATLQSKKNN 221

Query: 619 TRRSSLEFKESPVIKTPIEALLTPHSEQKRSP 714
            +R      E      P +    P   QK  P
Sbjct: 222 IKRDLEVLNEISASSKPSKYKNVPIWAQKWKP 253

>Q3ZJ90:RPOC2_PSEAK DNA-directed RNA polymerase beta'' chain - Pseudendoclonium akinetum|
            (Green alga)
          Length = 3462

 Score = 32.3 bits (72), Expect = 8.7
 Identities = 42/196 (21%), Positives = 75/196 (38%), Gaps = 18/196 (9%)
 Frame = +1

Query: 1348 QQIFVEK---FYINQNIKGKTDHNFTYNFLDYLTSISSRFLTAPSKGSPREK----LSPN 1506
            Q +FV K    Y+N+N + +     TY+F+D    + +RF    S      K    LS +
Sbjct: 2590 QVLFVSKKATHYLNENFRSQNYKKKTYDFIDNANVLKNRFFERLSPVEFHRKREGFLSKD 2649

Query: 1507 QSSPR---------LMAKSAFSATSSPFKRDRESTKHFTILASDPINF--PDNFIPPSTA 1653
            Q             L+     ++T +PF R  ++      + S        ++FI     
Sbjct: 2650 QKQMTFKYQNMQGGLIPALDSTSTFAPFARSSKARGSAKAIFSQAQRLWGEESFI----- 2704

Query: 1654 SKKNKASPSPLLFENNSDIQRHPTLITARNNGFVPILNMSNVTKPMTSLNYLSPRERNHT 1833
            + K K+  + ++F  NS  +    L     N  +  LN+       +++N+  P      
Sbjct: 2705 NDKQKSIRNQIIFAKNSRFKNLLILNNKNENEKLFYLNLKKKVSEQSTMNFFVPALYKKL 2764

Query: 1834 MMTSKEIKSAKKFYQV 1881
              T + I    KF +V
Sbjct: 2765 FYTKQSI---SKFLEV 2777

>P47405:RL29_MYCGE 50S ribosomal protein L29 - Mycoplasma genitalium|
          Length = 200

 Score = 32.3 bits (72), Expect = 8.7
 Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 23/200 (11%)
 Frame = +1

Query: 178 SKNSNVKNPKILVNPLVKLDGGINSARDKAQDFELRGPRLSG--------TLPPLNDAK- 330
           +K    K+ + LV  ++KL G +   R K    EL  P L           L  L + K 
Sbjct: 4   AKELKQKSNEELVKLVIKLKGELLEYRFKLAHGELDKPHLIAKVRKLLAVVLTILTERKL 63

Query: 331 NENRKKKFFTELHKPNNEKLSNRMIPNIVFTHANEGKEENKNV---PKLGVPPESLRETN 501
           N   +K  +  L +  NE + N     +  +   E K+E K     PK+   PES +ET 
Sbjct: 64  NWQVEKDKYKLLSRKTNELIVNSWKQKL--STKPESKQETKKAEVKPKVESKPESKQETK 121

Query: 502 KAMQKNSYNELVTL----------FKDSTSQNPTRVFDENPVPSARPIATRRSSLEFKES 651
           KA  K    E   +           K  T +   R+  +  V S +P+      +E K+S
Sbjct: 122 KAEVKPLKQETKKVEVKPKVEPKPLKQETKKVEARIETKTKVES-KPLKQEVKKVEAKKS 180

Query: 652 -PVIKTPIEALLTPHSEQKR 708
               + P++A +    E+K+
Sbjct: 181 VSKPQKPVKAKMIKTKEKKQ 200

>O94449:RFC4_SCHPO Replication factor C subunit 4 - Schizosaccharomyces pombe (Fission|
            yeast)
          Length = 342

 Score = 32.3 bits (72), Expect = 8.7
 Identities = 18/67 (26%), Positives = 31/67 (46%)
 Frame = -1

Query: 1137 VIVLDNEEEFTEKQFSLVKSVMEIYQNMLSFIFLS*NSFCHQINSIPNILKESCSEGKFS 958
            +I+LD  +  T      ++  MEIY N   F        C+Q N I   ++  C+  ++S
Sbjct: 122  IIILDEADSMTAGAQQALRRTMEIYSNTTRFALA-----CNQSNKIIEPIQSRCAILRYS 176

Query: 957  PILDTKV 937
             + D +V
Sbjct: 177  RLTDQQV 183

>Q8K3M6:ERC2_RAT ERC protein 2 - Rattus norvegicus (Rat)|
          Length = 957

 Score = 32.3 bits (72), Expect = 8.7
 Identities = 54/214 (25%), Positives = 92/214 (42%), Gaps = 6/214 (2%)
 Frame = +1

Query: 175  NSKNSNVKNPKILVNPLVKLDGGINSARDKAQDFELRGPRLSGTLPPLNDAKNENRKKKF 354
            N ++ +  NP+   + L +LD   +  RD+    +    RL   L  + + KN+  KK  
Sbjct: 690  NIEDDSRMNPEF-ADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIA 748

Query: 355  FTELHKPNNEKLSNRMIPNIVFTHANEGKEENKNVPKLGVPPESLRETNKAMQKNSYNEL 534
              E     + K  N+ + N+     N+  E+ KN   L    E +R    +M  NS +  
Sbjct: 749  ELESLTLRHMKDQNKKVANL---KHNQQLEKKKNAQLL----EEVRRREFSMVDNSQHLQ 801

Query: 535  VTLFKDSTSQNPTRVFDENPVPSARPIATRRSSLEFKESPVI------KTPIEALLTPHS 696
            +    ++  +  TR   E     AR +A+ + SL  KE+ +       +  +E +L    
Sbjct: 802  IEELMNALEK--TR--QELDATKAR-LASTQQSLAEKEAHLANLRMERRKQLEEILEMKQ 856

Query: 697  EQKRSPKNLKDPMQALREAEAIKNAKKTIEDLVA 798
            E   +  + KD   AL E  A K  KKT E+++A
Sbjct: 857  EALLAAISEKDANIALLELSASKK-KKTQEEVMA 889


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 359,165,421
Number of extensions: 7597184
Number of successful extensions: 20818
Number of sequences better than 10.0: 31
Number of HSP's gapped: 20786
Number of HSP's successfully gapped: 31
Length of query: 751
Length of database: 100,686,439
Length adjustment: 121
Effective length of query: 630
Effective length of database: 67,496,744
Effective search space: 42522948720
Effective search space used: 42522948720
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)