ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf13c03 |
|---|---|
| Clone Library Name | barley_pub |
>P70168:IMB1_MOUSE Importin subunit beta-1 - Mus musculus (Mouse)| Length = 876 Score = 563 bits (1451), Expect = e-159 Identities = 337/858 (39%), Positives = 500/858 (58%), Gaps = 26/858 (3%) Frame = +2 Query: 179 MDITQILLAAQSPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGII 358 M++ IL SPD AA+ +++ +NLP FL+ LS L+N +R AG+ Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60 Query: 359 LKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASI 538 +KNSL +KD K Q+W+++D + + ++K +L TLG+ ++SQ +A IA Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRP-SSASQCVAGIACA 119 Query: 539 EIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTAVV 718 EIP +W +LI +L++N+T P ++ +K++TLEA+GY+C++I PE L QD+ N +LTA++ Sbjct: 120 EIPVSQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQL-QDKSNEILTAII 178 Query: 719 QGMNQTELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAF 898 QGM + E S+ V+LAA AL N+L+F ++NF E ER FIM+V+C+ + +R AA Sbjct: 179 QGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAAL 238 Query: 899 ECLVAIASTYYVHLDPYM-QTIFNLTANAVKGDEEPVALQAVEFWSTICXXXXXXXXXXX 1075 + LV I S YY +++ YM +F +T A+K D + VALQ +EFWS +C Sbjct: 239 QNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEAS 298 Query: 1076 GSDDANSTVNYR---FIEKALPSLVPMLLETLLKQEEDQEQDDNAWNISMSGGTCLGLIA 1246 + + + + + AL LVP+L +TL KQ+E+ + DD WN + G CL L++ Sbjct: 299 EAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDD--WNPCKAAGVCLMLLS 356 Query: 1247 RTVGDAIVPLVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNT 1426 D IVP V+PF++ +I PDWR R+AA AFGSIL+GP +L PLV + L+ Sbjct: 357 TCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVVAFGSILEGPEPNQLKPLVIQAMPTLIEL 416 Query: 1427 MNDPNSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLESSKDVPNVAEKVC 1606 M DP+ V+DTTAWT+GR+ ELL I++ L ++ L+E P VA VC Sbjct: 417 MKDPSVVVRDTTAWTVGRICELLPEAA-----INDVYLAPLLQCLIEGLSAEPRVASNVC 471 Query: 1607 GAIYFLAQG-YEDA-------EPVSSLLTPYLPNVIAALLTAADRSDMTHVRLRASAYEA 1762 A LA+ YE A EP + L+ ++ LL DR D LR+SAYE+ Sbjct: 472 WAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYES 531 Query: 1763 LNEIVRVSN------IPETSSIIGQLLQEIMRRLNLTFDHQIFSSGDKEKQSDLQALLCG 1924 L EIV+ S + +T+ +I + LQ++++ + I S+ D+ + +DLQ+LLC Sbjct: 532 LMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQ-----MESHIQSTSDRIQFNDLQSLLCA 586 Query: 1925 VLQVIIQKLNSSDAKSIIAQTADQLMLLFLRVF--ACHSATVHEEAMLAIGALAYATGPD 2098 LQ +++K+ DA Q +D +M LR+F S V E+A++A+ L G + Sbjct: 587 TLQNVLRKVQHQDA----LQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGE 642 Query: 2099 FEKYMPEFLKYLEAGLQNYEEYQVCSISVGVVGDICRALEDKILPFCDGIMTVLLKDLSN 2278 F KYM F +L GL+NY EYQVC +VG+VGD+CRAL+ ILPFCD +M +LL++L N Sbjct: 643 FLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNILPFCDEVMQLLLENLGN 702 Query: 2279 SQLNRSVKPPIFSCFGDIALAIGENFEKYLPYAMPMLQGAAELLVVLDQNDEDMVDYGNQ 2458 ++RSVKP I S FGDIALAIG F+KYL + LQ A++ V D++D DMVDY N+ Sbjct: 703 ENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQV--DKSDFDMVDYLNE 760 Query: 2459 LRRGIFEAYSGILQGLKGAK------AQLMIPYAGHLLQFTEAVYKDGSRDESVTKAAVA 2620 LR EAY+GI+QGLKG + L+ P +L F + + D + V A Sbjct: 761 LRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAG 820 Query: 2621 VLGDLADTLGPISKDLFK 2674 ++GDL G KD+ K Sbjct: 821 LIGDLCTAFG---KDVLK 835
>Q14974:IMB1_HUMAN Importin subunit beta-1 - Homo sapiens (Human)| Length = 876 Score = 561 bits (1445), Expect = e-159 Identities = 335/858 (39%), Positives = 498/858 (58%), Gaps = 26/858 (3%) Frame = +2 Query: 179 MDITQILLAAQSPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGII 358 M++ IL SPD AA+ +++ +NLP FL+ LS L+N +R AG+ Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60 Query: 359 LKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASI 538 +KNSL +KD K Q+W+++D + + ++K +L TLG+ ++SQ +A IA Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRP-SSASQCVAGIACA 119 Query: 539 EIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTAVV 718 EIP +W +LI +L++N+T P ++ +K++TLEA+GY+C++I PE L QD+ N +LTA++ Sbjct: 120 EIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQL-QDKSNEILTAII 178 Query: 719 QGMNQTELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAF 898 QGM + E S+ V+LAA AL N+L+F ++NF E ER FIM+V+C+ + +R AA Sbjct: 179 QGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAAL 238 Query: 899 ECLVAIASTYYVHLDPYM-QTIFNLTANAVKGDEEPVALQAVEFWSTICXXXXXXXXXXX 1075 + LV I S YY +++ YM +F +T A+K D + VALQ +EFWS +C Sbjct: 239 QNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEAS 298 Query: 1076 GSDDANSTVNYR---FIEKALPSLVPMLLETLLKQEEDQEQDDNAWNISMSGGTCLGLIA 1246 + + + + + AL LVP+L +TL KQ+E+ + DD WN + G CL L+A Sbjct: 299 EAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDD--WNPCKAAGVCLMLLA 356 Query: 1247 RTVGDAIVPLVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNT 1426 D IVP V+PF++ +I PDWR R+AA AFG IL+GP +L PLV + L+ Sbjct: 357 TCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIEL 416 Query: 1427 MNDPNSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLESSKDVPNVAEKVC 1606 M DP+ V+DT AWT+GR+ ELL I++ L ++ L+E P VA VC Sbjct: 417 MKDPSVVVRDTAAWTVGRICELLPEAA-----INDVYLAPLLQCLIEGLSAEPRVASNVC 471 Query: 1607 GAIYFLAQG-YEDA-------EPVSSLLTPYLPNVIAALLTAADRSDMTHVRLRASAYEA 1762 A LA+ YE A EP + L+ ++ LL DR D LR+SAYE+ Sbjct: 472 WAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYES 531 Query: 1763 LNEIVRVSN------IPETSSIIGQLLQEIMRRLNLTFDHQIFSSGDKEKQSDLQALLCG 1924 L EIV+ S + +T+ +I + LQ++++ + I S+ D+ + +DLQ+LLC Sbjct: 532 LMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQ-----MESHIQSTSDRIQFNDLQSLLCA 586 Query: 1925 VLQVIIQKLNSSDAKSIIAQTADQLMLLFLRVF--ACHSATVHEEAMLAIGALAYATGPD 2098 LQ +++K+ DA Q +D +M LR+F S V E+A++A+ L G + Sbjct: 587 TLQNVLRKVQHQDA----LQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGE 642 Query: 2099 FEKYMPEFLKYLEAGLQNYEEYQVCSISVGVVGDICRALEDKILPFCDGIMTVLLKDLSN 2278 F KYM F +L GL+NY EYQVC +VG+VGD+CRAL+ I+PFCD +M +LL++L N Sbjct: 643 FLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGN 702 Query: 2279 SQLNRSVKPPIFSCFGDIALAIGENFEKYLPYAMPMLQGAAELLVVLDQNDEDMVDYGNQ 2458 ++RSVKP I S FGDIALAIG F+KYL + LQ A++ V D++D DMVDY N+ Sbjct: 703 ENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQV--DKSDYDMVDYLNE 760 Query: 2459 LRRGIFEAYSGILQGLKGAK------AQLMIPYAGHLLQFTEAVYKDGSRDESVTKAAVA 2620 LR EAY+GI+QGLKG + L+ P +L F + + D + V A Sbjct: 761 LRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAG 820 Query: 2621 VLGDLADTLGPISKDLFK 2674 ++GDL G KD+ K Sbjct: 821 LIGDLCTAFG---KDVLK 835
>O13864:IMB1_SCHPO Importin subunit beta-1 - Schizosaccharomyces pombe (Fission yeast)| Length = 863 Score = 547 bits (1409), Expect = e-154 Identities = 330/832 (39%), Positives = 476/832 (57%), Gaps = 10/832 (1%) Frame = +2 Query: 179 MDITQILLAAQSPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGII 358 M+ + L SPD N+R AE ++ + +++ L+ EL+ND P R AG+ Sbjct: 1 MNAGEFLAQTLSPDANVRLNAEKQLENAARTDFAQYMVLLAQELANDNSMPYIRMAAGLA 60 Query: 359 LKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASI 538 LKN++ A++ ARK Q W SL IK Q+K L TLGSS A Q+++Q++A IA+ Sbjct: 61 LKNAITAREEARKLEYQQLWQSLPVEIKQQVKSLALQTLGSSEHQAGQSAAQLVAAIAAY 120 Query: 539 EIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTAVV 718 E+ +W DL+ L++N+ + G + LKQ +L+ +GY+CE + PE L Q NA+LTAVV Sbjct: 121 ELATNQWPDLMVTLVANVGE-GQPSALKQHSLQTIGYICESVSPEVLSA-QSNAILTAVV 178 Query: 719 QGMNQTELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAF 898 G + E + VRLAA+ ALY++L+F NF NE ER +IM+V+C+ S E I+ AAF Sbjct: 179 AGARKEEPDAAVRLAALGALYDSLEFVRENFNNEYERNYIMQVVCEATQSPEASIQTAAF 238 Query: 899 ECLVAIASTYYVHLDPYMQ-TIFNLTANAVKGDEEPVALQAVEFWSTICXXXXXXXXXXX 1075 CLV I YY + YM+ +F LT + E VALQAVEFWST+C Sbjct: 239 GCLVKIMHLYYDTMPFYMEKALFALTTQGMYNTNEQVALQAVEFWSTVCEEEIEVNLEIQ 298 Query: 1076 GSDDANSTV---NYRFIEKALPSLVPMLLETLLKQEEDQEQDDNAWNISMSGGTCLGLIA 1246 + D N N+ F A ++P+LL+ L Q+ED ++DD WNISM+ TCL L A Sbjct: 299 EAQDLNEVPARQNHGFARAAAADILPVLLKLLCNQDEDADEDD--WNISMAAATCLQLFA 356 Query: 1247 RTVGDAIVPLVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNT 1426 + VGD IV V+ FVE NI PDW REAA AFGS+L+GP++ L PLV L L+N Sbjct: 357 QVVGDLIVNPVLAFVEQNIQNPDWHQREAAVMAFGSVLEGPNVAMLTPLVNQALPVLINM 416 Query: 1427 MNDPNSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLESSKDVPNVAEKVC 1606 M DP VKDTTAW LG++ + + NP I +L +++ LL+ D P + C Sbjct: 417 MVDPVIFVKDTTAWALGQISSFVAD--AINPEI---HLSPMVSALLQGLTDNPRIVANCC 471 Query: 1607 GAIYFLAQGYEDAEP-VSSLLTPYLPNVIAALLTAADRSDMTHVRLRASAYEALNEIVRV 1783 A L + + +S++TP+ +I +LL D+ + R S YE L ++ Sbjct: 472 WAFMNLVCHFAPVDNHQTSVMTPFYEAIIGSLLHVTDQKGNEN-NSRTSGYETLGTLITF 530 Query: 1784 SNIPETSSIIGQLLQEIMRRL--NLTFDHQIFSSGDKEKQSDLQALLCGVLQVIIQKLNS 1957 S+ +I +L I+ RL ++ QI D+ +LQ+ LC VL II++ Sbjct: 531 SS-DSVLPMIANVLSIILTRLETSIQMQSQILDVEDRANHDELQSNLCNVLTSIIRRFGP 589 Query: 1958 SDAKSIIAQTADQLMLLFLRVF--ACHSATVHEEAMLAIGALAYATGPDFEKYMPEFLKY 2131 I ++DQ+M L L+ A + VHE+ +LAIGA+ + FE Y+P F+ + Sbjct: 590 D-----IRTSSDQIMNLLLQTMQTAPKQSVVHEDVLLAIGAMMNSLEEQFEVYVPSFVPF 644 Query: 2132 LEAGLQNYEEYQVCSISVGVVGDICRALEDKILPFCDGIMTVLLKDLSNSQLNRSVKPPI 2311 L + L N +EYQ+CS++VG+VGD+ RAL KILP+CD MT L++DL +S L+R+VKP I Sbjct: 645 LSSALSNEQEYQLCSVAVGLVGDLARALNAKILPYCDDFMTRLVQDLQSSVLDRNVKPAI 704 Query: 2312 FSCFGDIALAIGENFEKYLPYAMPMLQGAAELLVVLDQNDEDMVDYGNQLRRGIFEAYSG 2491 SCF DIALAIG F+ YL M +LQ A+ + N M+DY + LR GI EAY G Sbjct: 705 LSCFSDIALAIGAAFQTYLEAVMVLLQQASSVQAPPGAN-FSMIDYVDALRLGIVEAYVG 763 Query: 2492 ILQGLK-GAKAQLMIPYAGHLLQFTEAVYKDGSRDESVTKAAVAVLGDLADT 2644 I Q ++ + L+ PY + + D ES+T+AA+ +LGDLA++ Sbjct: 764 ITQAVRTDNRLDLIQPYVHSMFTLLNMITADPECSESLTRAALGLLGDLAES 815
>P52296:IMB1_RAT Importin subunit beta-1 - Rattus norvegicus (Rat)| Length = 875 Score = 547 bits (1409), Expect = e-154 Identities = 332/858 (38%), Positives = 495/858 (57%), Gaps = 26/858 (3%) Frame = +2 Query: 179 MDITQILLAAQSPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGII 358 M++ IL SPD AA+ +++ +NLP FL+ LS L+N +R AG+ Sbjct: 1 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ 60 Query: 359 LKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASI 538 ++ L +KD K Q+W+++D + + ++K +L TLG+ ++SQ +A IA Sbjct: 61 IR-LLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRP-SSASQCVAGIACA 118 Query: 539 EIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTAVV 718 EIP +W +LI +L++N+T P ++ +K++TLEA+GY+C++I PE L QD+ N +LTA++ Sbjct: 119 EIPVSQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQL-QDKSNEILTAII 177 Query: 719 QGMNQTELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAF 898 QGM + E S+ V+LAA AL N+L+F ++NF E ER FIM+V+C+ + +R AA Sbjct: 178 QGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAAL 237 Query: 899 ECLVAIASTYYVHLDPYM-QTIFNLTANAVKGDEEPVALQAVEFWSTICXXXXXXXXXXX 1075 + LV I S YY +++ YM +F +T A+K D + VALQ +EFWS +C Sbjct: 238 QNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEAS 297 Query: 1076 GSDDANSTVNYR---FIEKALPSLVPMLLETLLKQEEDQEQDDNAWNISMSGGTCLGLIA 1246 + + + + + AL LVP+L +TL KQ+E+ + DD WN + G CL L++ Sbjct: 298 EAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDD--WNPCKAAGVCLMLLS 355 Query: 1247 RTVGDAIVPLVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNT 1426 D IVP V+PF++ +I PDWR R+AA AFGSIL+GP +L PLV + L+ Sbjct: 356 TCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGSILEGPEPNQLKPLVIQAMPTLIEL 415 Query: 1427 MNDPNSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLESSKDVPNVAEKVC 1606 M DP+ V+DTTAWT+GR+ ELL I++ L ++ L+E P VA VC Sbjct: 416 MKDPSVVVRDTTAWTVGRICELLPEAA-----INDVYLAPLLQCLIEGLSAEPRVASNVC 470 Query: 1607 GAIYFLAQG-YEDA-------EPVSSLLTPYLPNVIAALLTAADRSDMTHVRLRASAYEA 1762 A LA+ YE A EP + L+ ++ LL DR D LR+SAYE+ Sbjct: 471 WAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYES 530 Query: 1763 LNEIVRVSN------IPETSSIIGQLLQEIMRRLNLTFDHQIFSSGDKEKQSDLQALLCG 1924 L EIV+ S + +T+ +I + LQ++++ + I S+ D+ + +DLQ+LLC Sbjct: 531 LMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQ-----MESHIQSTSDRIQFNDLQSLLCA 585 Query: 1925 VLQVIIQKLNSSDAKSIIAQTADQLMLLFLRVF--ACHSATVHEEAMLAIGALAYATGPD 2098 LQ ++ K+ DA Q +D +M LR+F S V E+A++A+ L G + Sbjct: 586 TLQNVLWKVQHQDA----LQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGE 641 Query: 2099 FEKYMPEFLKYLEAGLQNYEEYQVCSISVGVVGDICRALEDKILPFCDGIMTVLLKDLSN 2278 F KYM F +L GL+NY E QVC +VG+VGD+CRAL+ ILPFCD +M +LL++L N Sbjct: 642 FLKYMEAFKPFLGIGLKNYAECQVCLAAVGLVGDLCRALQSNILPFCDEVMQLLLENLGN 701 Query: 2279 SQLNRSVKPPIFSCFGDIALAIGENFEKYLPYAMPMLQGAAELLVVLDQNDEDMVDYGNQ 2458 ++RSVKP I S FGDI LAIG F+KYL + LQ A++ V D++D DMVDY N+ Sbjct: 702 ENVHRSVKPQILSVFGDITLAIGGEFKKYLEVVLNTLQQASQAQV--DKSDFDMVDYLNE 759 Query: 2459 LRRGIFEAYSGILQGLKGAK------AQLMIPYAGHLLQFTEAVYKDGSRDESVTKAAVA 2620 LR EAY+GI+QGLKG + L+ P +L F + + D + V A Sbjct: 760 LRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAG 819 Query: 2621 VLGDLADTLGPISKDLFK 2674 ++GDL G KD+ K Sbjct: 820 LIGDLCTAFG---KDVLK 834
>O18388:IMB_DROME Importin subunit beta - Drosophila melanogaster (Fruit fly)| Length = 884 Score = 523 bits (1346), Expect = e-147 Identities = 310/847 (36%), Positives = 476/847 (56%), Gaps = 22/847 (2%) Frame = +2 Query: 179 MDITQILLAAQSPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGII 358 M + IL SPD N +A+ ++Q NLP FL +LS L N +R AG+ Sbjct: 7 MQLIAILEKTVSPDKNELLSAKNFLEQAAASNLPEFLKALSEILVNTANSAVARMAAGLQ 66 Query: 359 LKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASI 538 LKN L +KD + +W I+ IK ++L LG+ ++Q +A +A I Sbjct: 67 LKNHLTSKDEKVSQQYQDRWHQFPSEIRELIKNNILAALGTE-NTRPSCAAQCVAYVAVI 125 Query: 539 EIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTAVV 718 E+P W LI L++ + G+S +++ LEA+GY+C++I +E +Q N VLTA++ Sbjct: 126 ELPINRWPMLIQTLVNKVVSEGSSEMHRESALEAIGYICQDIRFGVME-NQSNDVLTAII 184 Query: 719 QGMNQTELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAF 898 GM + E S+ VRLAA AL+N+L+F +SNF +MER FIM+V+C+ ++ +I AA Sbjct: 185 HGMRKVEPSNHVRLAATTALHNSLEFTKSNFEKDMERNFIMEVVCEATQCQDSQICVAAL 244 Query: 899 ECLVAIASTYYVHLDPYM-QTIFNLTANAVKGDEEPVALQAVEFWSTICXXXXXXXXXXX 1075 +CLV I + YY +++PYM Q +F +T A+K D + VALQ +EFWS +C Sbjct: 245 QCLVKIMTLYYQYMEPYMAQALFPITLAAMKSDNDAVALQGIEFWSNVCDEEIDLAIESQ 304 Query: 1076 GSDD---ANSTVNYRFIEKALPSLVPMLLETLLKQEEDQEQDDNAWNISMSGGTCLGLIA 1246 + D A V+ + AL L P+L+E L KQ+E ++D W+ + + CL ++A Sbjct: 305 EATDQGRAPQRVSKHYARGALQFLTPVLVEKLTKQDECDDED--TWSPAKAASVCLMVLA 362 Query: 1247 RTVGDAIVPLVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNT 1426 D IVP V+PF++ NI P+WR R+AA FGS+L+G L PLV+ + L+ Sbjct: 363 TCCEDEIVPHVLPFIKENIESPNWRFRDAAVMTFGSVLNGLETNTLKPLVEQAMPTLIRL 422 Query: 1427 MNDPNSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLESSKDVPNVAEKVC 1606 M D + V+DT AWT GR+ +++ I+ L ++ ++S K P VA VC Sbjct: 423 MYDSSVIVRDTIAWTFGRICDIIPEAA-----INETYLQTLLECFVKSLKSEPRVAANVC 477 Query: 1607 GAIYFLAQGYEDAE-------PVSSLLTPYLPNVIAALLTAADRSDMTHVRLRASAYEAL 1765 A L+ +A P + L+PY +I LL DRSD LR +AY+AL Sbjct: 478 WAFIGLSDAAWEAAVTNDGETPETYALSPYFEYIITQLLETTDRSDGAQANLRCAAYQAL 537 Query: 1766 NEIVRVSNIPETSSIIGQLLQEIMRRLN--LTFDHQIFSSGDKEKQSDLQALLCGVLQVI 1939 ++++ S + + ++ + I+ RLN + + QI + D+ + +DLQ+LLC LQ + Sbjct: 538 MDMIKNSPL-DCYLVVQRTTLVILERLNQVMQMETQINNHSDRHQFNDLQSLLCATLQSV 596 Query: 1940 IQKLNSSDAKSIIAQTADQLMLLFLRVF---ACHSATVHEEAMLAIGALAYATGPDFEKY 2110 ++K++ DA I +D +M L +F A S V EEA LA+ L G F KY Sbjct: 597 LRKVHEQDAPQI----SDAIMTALLTMFNSSAGKSGVVQEEAFLAVSTLVELLGAQFAKY 652 Query: 2111 MPEFLKYLEAGLQNYEEYQVCSISVGVVGDICRALEDKILPFCDGIMTVLLKDLSNSQLN 2290 MP F +L GL+N++EYQVC +VG+ GDI RAL+D ++P+ + IMTVL+ +L+ ++ Sbjct: 653 MPAFKDFLVMGLKNFQEYQVCCAAVGLTGDIFRALKDLMVPYSNEIMTVLINNLTEPTIH 712 Query: 2291 RSVKPPIFSCFGDIALAIGENFEKYLPYAMPMLQGAAELLVVLDQNDEDMVDYGNQLRRG 2470 R+VKP + S FGDIAL+IG +F YL + ML+ A+ L D N+ DM +Y N+LR Sbjct: 713 RTVKPQVLSAFGDIALSIGNHFLPYLSMVLDMLRVASNLQT--DANNFDMNEYINELRES 770 Query: 2471 IFEAYSGILQGLKG------AKAQLMIPYAGHLLQFTEAVYKDGSRDESVTKAAVAVLGD 2632 I EAY+GI+QGLKG M P+ H++ F + + ++G +S+ +A +GD Sbjct: 771 ILEAYTGIIQGLKGVDQTAHTDVMHMEPHLMHIISFIKRIAQEGDVSDSMLASAAGFIGD 830 Query: 2633 LADTLGP 2653 L + GP Sbjct: 831 LCTSFGP 837
>Q06142:IMB1_YEAST Importin subunit beta-1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 861 Score = 424 bits (1090), Expect = e-117 Identities = 289/861 (33%), Positives = 440/861 (51%), Gaps = 13/861 (1%) Frame = +2 Query: 212 SPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGIILKNSLDAKDSA 391 SPD N+R +E +K+ N F S L ++ E R LA + LKN L +KDS Sbjct: 16 SPDQNIRLTSETQLKKLSNDNFLQFAGLSSQVLIDENTKLEGRILAALTLKNELVSKDSV 75 Query: 392 RKELLIQQWVS-LDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASIEIPRREWQDL 568 + + Q+W++ + K+QIK + L L S ++Q+IA IA IE+P W +L Sbjct: 76 KTQQFAQRWITQVSPEAKNQIKTNALTALVSIEPRIANAAAQLIAAIADIELPHGAWPEL 135 Query: 569 IAKLLSNMTQPGASAP--LKQATLEALGYVCEEIPPEHLEQ-DQVNAVLTAVVQGMNQTE 739 + ++ N GA P +K+A+L ALGY+CE P+ N +L A+VQG TE Sbjct: 136 MKIMVDNT---GAEQPENVKRASLLALGYMCESADPQSQALVSSSNNILIAIVQGAQSTE 192 Query: 740 LSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAFECLVAIA 919 S VRLAA+ AL ++L F ++N E ER ++M+V+C+ ++++E++ AAF CL I Sbjct: 193 TSKAVRLAALNALADSLIFIKNNMEREGERNYLMQVVCEATQAEDIEVQAAAFGCLCKIM 252 Query: 920 STYYVHLDPYM-QTIFNLTANAVKGDEEPVALQAVEFWSTICXXXXXXXXXXXGSDDANS 1096 S YY + PYM Q ++ LT +K + VA VEFWSTIC + Sbjct: 253 SLYYTFMKPYMEQALYALTIATMKSPNDKVASMTVEFWSTICEEEIDIAYEL-AQFPQSP 311 Query: 1097 TVNYRFIEKALPSLVPMLLETLLKQEEDQEQDDNAWNISMSGGTCLGLIARTVGDAIVPL 1276 +Y F ++ +VP LL L +Q ED E DD WN+SMS G CL L A+ G+ I+ Sbjct: 312 LQSYNFALSSIKDVVPNLLNLLTRQNEDPEDDD--WNVSMSAGACLQLFAQNCGNHILEP 369 Query: 1277 VMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNTMNDPNSQVKD 1456 V+ FVE NIT +WR REAA AFGSI+DGP + V L +LN MND + QVK+ Sbjct: 370 VLEFVEQNITADNWRNREAAVMAFGSIMDGPDKVQRTYYVHQALPSILNLMNDQSLQVKE 429 Query: 1457 TTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLESSKDVPNVAEKVCGAIYFLAQGY 1636 TTAW +GR+ + + I +LP ++ L +D P VA I L + Sbjct: 430 TTAWCIGRIADSV-----AESIDPQQHLPGVVQACLIGLQDHPKVATNCSWTIINLVEQL 484 Query: 1637 EDAEPVSSLLTPYLPNVIAALLTAADRSDMTHVRLRASAYEALNEIVR--VSNIPETSSI 1810 +A P S + + P ++ L+ AA+R D RASA+ AL +V + ETS+ Sbjct: 485 AEATP--SPIYNFYPALVDGLIGAANRID-NEFNARASAFSALTTMVEYATDTVAETSAS 541 Query: 1811 IGQLLQEIMRRLNLTFDHQIFSSGDKEKQSDLQALLCGVLQVIIQKLNSSDAKSIIAQTA 1990 I + + + + ++ D + D + +LQ+ + VL +I+K SS + A Sbjct: 542 ISTFVMDKLGQ-TMSVDENQLTLEDAQSLQELQSNILTVLAAVIRKSPSS-----VEPVA 595 Query: 1991 DQLMLLFLRVF-ACHSATVHEEAMLAIGALAYATGPDFEKYMPEFLKYLEAGLQNYEEYQ 2167 D LM LF R+ SA + ++ AI ALA + G FEKY+ F YL L N + Sbjct: 596 DMLMGLFFRLLEKKDSAFIEDDVFYAISALAASLGKGFEKYLETFSPYLLKAL-NQVDSP 654 Query: 2168 VCSISVGVVGDICRALEDKILPFCDGIMTVLLKDLSNSQLNRSVKPPIFSCFGDIALAIG 2347 V +VG + DI +LE+ + D +M VL + +SN R +KP + S FGDIA IG Sbjct: 655 VSITAVGFIADISNSLEEDFRRYSDAMMNVLAQMISNPNARRELKPAVLSVFGDIASNIG 714 Query: 2348 ENFEKYLPYAMPMLQGAAELLVVLDQNDEDMVDYGNQLRRGIFEAYSGILQGLKGAKAQL 2527 +F YL M + A + + +DY ++ + +AY GI+ GL K + Sbjct: 715 ADFIPYLNDIMALCVAAQN--TKPENGTLEALDYQIKVLEAVLDAYVGIVAGLHD-KPEA 771 Query: 2528 MIPYAGHLLQFTEAVYKDGS--RDESVTKAAVAVLGDLADTLGPISKDLFKSHLFHVEFL 2701 + PY G + QF V +D +++ ++AAV ++GD+A S F + ++++ Sbjct: 772 LFPYVGTIFQFIAQVAEDPQLYSEDATSRAAVGLIGDIAAMFPDGSIKQFYGQDWVIDYI 831 Query: 2702 RECLD---LDDEVRETASWTQ 2755 + ++TA W + Sbjct: 832 KRTRSGQLFSQATKDTARWAR 852
>Q8BFY9:TNPO1_MOUSE Transportin-1 - Mus musculus (Mouse)| Length = 890 Score = 108 bits (271), Expect = 1e-22 Identities = 167/806 (20%), Positives = 319/806 (39%), Gaps = 68/806 (8%) Frame = +2 Query: 176 VMDITQILLAAQSPDGNLRSAAEANIKQF-QEQNLPNFLLSLSVELSNDERPPESRRLAG 352 + I Q+L +QSPD ++ + ++Q Q + N+L+ + +L +++ P +R L+G Sbjct: 12 LQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEP--TRSLSG 69 Query: 353 IILKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIA 532 +ILKN++ A + + + + IK L +G S R T +I IA Sbjct: 70 LILKNNVKA-----------HFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIA 118 Query: 533 SIEIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTA 712 S + + W DL+ KL S + + + AL +CE+ E L+ D ++ L Sbjct: 119 S-KGELQNWPDLLPKLCSLLDSEDYNTC--EGAFGALQKICED-SAEILDSDVLDRPLNI 174 Query: 713 VVQGMNQ--TELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIR 886 ++ Q S ++R AV A N + + +FI + A +E E+R Sbjct: 175 MIPKFLQFFKHSSPKIRSHAV-ACVNQFIISRTQALMLHIDSFIENLFA-LAGDEEAEVR 232 Query: 887 QAAFECLVAIASTYYVHLDPYMQTIFNLTANAVKGDEEPVALQAVEFWSTICXXXXXXXX 1066 + LV + L P+M I + +E VAL+A EFW T+ Sbjct: 233 KNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTL--------- 283 Query: 1067 XXXGSDDANSTVNYRFIEKALPSLVPMLL--------------------ETLLKQEED-- 1180 A + + + LP L+P+L+ ET+ E+D Sbjct: 284 -------AEQPICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIR 336 Query: 1181 ------------------QEQDD-----------NAWNISMSGGTCLGLIARTVGDAIVP 1273 +E+DD + WN+ L ++A D ++P Sbjct: 337 PRFHRSRTVAQQHEEDGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLP 396 Query: 1274 LVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNTMNDPNSQVK 1453 ++P ++ + +W +E+ G+I +G ++ + P + + L+ ++D + V+ Sbjct: 397 HILPLLKELLFHHEWVVKESGILVLGAIAEG-CMQGMIPYLPELIPHLIQCLSDKKALVR 455 Query: 1454 DTTAWTLGRVFE-LLHSPCST--NPIISNANLPRIMAVLLESSKDVPNVAEKVCGAIYFL 1624 T WTL R ++ P T P+++ ++ +L+S+K V E C A L Sbjct: 456 SITCWTLSRYAHWVVSQPPDTYLKPLMT-----ELLKRILDSNK---RVQEAACSAFATL 507 Query: 1625 AQGYEDAEPVSSLLTPYLPNVIAALLTAADRSDMTHVRLRASAYEALNEIV-RVSNIPET 1801 E + L PYL ++ L+ A + ++ + A L + V N PE Sbjct: 508 ------EEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPE- 560 Query: 1802 SSIIGQLLQEIMRRLNLTFDH--------QIFSSGDKEKQSDLQALLCGVLQVIIQKLNS 1957 I L+ ++++ N+ D + SS QS V Q + + Sbjct: 561 --YIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQK 618 Query: 1958 SDAKSIIAQTADQLMLLFLRVFACHSATVHEEAMLAIGALAYATGPDFEKYM--PEFLKY 2131 + A++++ + + A+ + LA G + E+ + L Sbjct: 619 TLAQAMLNNAQPE-------QYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTL 671 Query: 2132 LEAGLQNYEEYQVCSISVGVVGDICRALEDKILPFCDGIMTVLLKDLSNSQLNRSVKPPI 2311 + +Q+ + +V S ++GD+ +A + P M +L +L+ + SV Sbjct: 672 MYQCMQD-KMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFI--SVCNNA 728 Query: 2312 FSCFGDIALAIGENFEKYLPYAMPML 2389 G+I++ +G + Y+P + L Sbjct: 729 TWAIGEISIQMGIEMQPYIPMVLHQL 754
>Q92973:TNPO1_HUMAN Transportin-1 - Homo sapiens (Human)| Length = 890 Score = 108 bits (269), Expect = 2e-22 Identities = 171/810 (21%), Positives = 322/810 (39%), Gaps = 72/810 (8%) Frame = +2 Query: 176 VMDITQILLAAQSPDGNLRSAAEANIKQF-QEQNLPNFLLSLSVELSNDERPPESRRLAG 352 + I Q+L +QSPD ++ + ++Q Q + N+L+ + +L +++ P +R L+G Sbjct: 12 LQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEP--TRSLSG 69 Query: 353 IILKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIA 532 +ILKN++ A + + + + IK L +G S R T +I IA Sbjct: 70 LILKNNVKA-----------HFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIA 118 Query: 533 SIEIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTA 712 S + + W DL+ KL S + + + AL +CE+ E L+ D ++ L Sbjct: 119 S-KGELQNWPDLLPKLCSLLDSEDYNTC--EGAFGALQKICED-SAEILDSDVLDRPLNI 174 Query: 713 VVQGMNQ--TELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIR 886 ++ Q S ++R AV A N + + +FI + A +E E+R Sbjct: 175 MIPKFLQFFKHSSPKIRSHAV-ACVNQFIISRTQALMLHIDSFIENLFA-LAGDEEPEVR 232 Query: 887 QAAFECLVAIASTYYVHLDPYMQTIFNLTANAVKGDEEPVALQAVEFWSTICXXXXXXXX 1066 + LV + L P+M I + +E VAL+A EFW T+ Sbjct: 233 KNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTL--------- 283 Query: 1067 XXXGSDDANSTVNYRFIEKALPSLVPMLL--------------------ETLLKQEED-- 1180 A + + + LP L+P+L+ ET+ E+D Sbjct: 284 -------AEQPICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIR 336 Query: 1181 ------------------QEQDD-----------NAWNISMSGGTCLGLIARTVGDAIVP 1273 +E+DD + WN+ L ++A D ++P Sbjct: 337 PRFHRSRTVAQQHDEDGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLP 396 Query: 1274 LVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNTMNDPNSQVK 1453 ++P ++ + +W +E+ G+I +G ++ + P + + L+ ++D + V+ Sbjct: 397 HILPLLKELLFHHEWVVKESGILVLGAIAEG-CMQGMIPYLPELIPHLIQCLSDKKALVR 455 Query: 1454 DTTAWTLGRVFE-LLHSPCST--NPIISNANLPRIMAVLLESSKDVPNVAEKVCGAIYFL 1624 T WTL R ++ P T P+++ ++ +L+S+K V E C A L Sbjct: 456 SITCWTLSRYAHWVVSQPPDTYLKPLMT-----ELLKRILDSNK---RVQEAACSAFATL 507 Query: 1625 AQGYEDAEPVSSLLTPYLPNVIAALLTAADRSDMTHVRLRASAYEALNEIV-RVSNIPET 1801 E + L PYL ++ L+ A + ++ + A L + V N PE Sbjct: 508 ------EEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPE- 560 Query: 1802 SSIIGQLLQEIMRRLNLTFDHQIFSSGDKEKQSDLQALLCGVLQVIIQKLNS-------- 1957 I L+ ++++ N+ K++ DL LL L + L S Sbjct: 561 --YIQMLMPPLIQKWNML----------KDEDKDLFPLL-ECLSSVATALQSGFLPYCEP 607 Query: 1958 --SDAKSIIAQTADQLMLLFLR--VFACHSATVHEEAMLAIGALAYATGPDFEKYM--PE 2119 +++ +T Q ML + + A+ + LA G + E+ + Sbjct: 608 VYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSN 667 Query: 2120 FLKYLEAGLQNYEEYQVCSISVGVVGDICRALEDKILPFCDGIMTVLLKDLSNSQLNRSV 2299 L + +Q+ + +V S ++GD+ +A + P M +L +L+ + SV Sbjct: 668 ILTLMYQCMQD-KMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFI--SV 724 Query: 2300 KPPIFSCFGDIALAIGENFEKYLPYAMPML 2389 G+I++ +G + Y+P + L Sbjct: 725 CNNATWAIGEISIQMGIEMQPYIPMVLHQL 754
>Q99LG2:TNPO2_MOUSE Transportin-2 - Mus musculus (Mouse)| Length = 887 Score = 100 bits (250), Expect = 3e-20 Identities = 117/549 (21%), Positives = 218/549 (39%), Gaps = 38/549 (6%) Frame = +2 Query: 176 VMDITQILLAAQSPDGNLRSAAEANIKQFQE-QNLPNFLLSLSVELSNDERPPESRRLAG 352 + + Q+L +QSP+ + + +KQ + + N+L+ + L +++ P +R L+G Sbjct: 10 LQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEP--TRSLSG 67 Query: 353 IILKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIA 532 +ILKN++ A + S + IK+ L +G + R T +I IA Sbjct: 68 LILKNNVKA-----------HYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIA 116 Query: 533 SIEIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTA 712 S + + W +L+ +L + + + + AL +CE+ E L+ D +N L Sbjct: 117 S-KGELQMWPELLPQLCNLLNSEDYNTC--EGAFGALQKICED-SSELLDSDALNRPLNI 172 Query: 713 VVQGMNQ--TELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIR 886 ++ Q S ++R A+ A N + + TFI + AV + E+R Sbjct: 173 MIPKFLQFFKHCSPKIRSHAI-ACVNQFIMDRAQALMDNIDTFIEHLFA-LAVDDDPEVR 230 Query: 887 QAAFECLVAIASTYYVHLDPYMQTIFNLTANAVKGDEEPVALQAVEFWSTIC-------- 1042 + LV + L P+M +I + +E VAL+A EFW T+ Sbjct: 231 KNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEV 290 Query: 1043 -----------------------XXXXXXXXXXXGSDDANSTVNYRFIEKALPSLVPMLL 1153 D+ + RF + +L Sbjct: 291 LASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLTHEAE 350 Query: 1154 ETLLKQEEDQEQDDNA---WNISMSGGTCLGLIARTVGDAIVPLVMPFVEANITKPDWRC 1324 ++ + + DD+A WN+ L ++A + ++P ++P ++ + P+W Sbjct: 351 RPDSSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVV 410 Query: 1325 REAATFAFGSILDGPSLEKLAPLVQAGLDFLLNTMNDPNSQVKDTTAWTLGRVFELLHSP 1504 +E+ G+I +G ++ + P + + L+ ++D + V+ WTL R H Sbjct: 411 KESGILVLGAIAEG-CMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSR---YAHWV 466 Query: 1505 CSTNPIISNANLPRIMAVLLESSKD-VPNVAEKVCGAIYFLAQGYEDAEPVSSLLTPYLP 1681 S P + +L +M LL+ D V E C A L E + L PYL Sbjct: 467 VSQPP---DMHLKPLMTELLKRILDGNKRVQEAACSAFATL------EEEACTELVPYLS 517 Query: 1682 NVIAALLTA 1708 ++ L+ A Sbjct: 518 YILDTLVFA 526
>O14787:TNPO2_HUMAN Transportin-2 - Homo sapiens (Human)| Length = 897 Score = 99.4 bits (246), Expect = 8e-20 Identities = 119/550 (21%), Positives = 219/550 (39%), Gaps = 39/550 (7%) Frame = +2 Query: 176 VMDITQILLAAQSPDGNLRSAAEANIKQFQE-QNLPNFLLSLSVELSNDERPPESRRLAG 352 + + Q+L +QSP+ + + +KQ + + N+L+ + L +++ P +R L+G Sbjct: 10 LQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEP--TRSLSG 67 Query: 353 IILKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIA 532 +ILKN++ A + S + IK+ L +G + R T +I IA Sbjct: 68 LILKNNVKA-----------HYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIA 116 Query: 533 SIEIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTA 712 S + + W +L+ +L + + + + AL +CE+ E L+ D +N L Sbjct: 117 S-KGELQMWPELLPQLCNLLNSEDYNTC--EGAFGALQKICED-SSELLDSDALNRPLNI 172 Query: 713 VVQGMNQ--TELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIR 886 ++ Q S ++R A+ A N + + TFI + AV + E+R Sbjct: 173 MIPKFLQFFKHCSPKIRSHAI-ACVNQFIMDRAQALMDNIDTFIEHLFA-LAVDDDPEVR 230 Query: 887 QAAFECLVAIASTYYVHLDPYMQTIFNLTANAVKGDEEPVALQAVEFWSTIC-------- 1042 + LV + L P+M +I + +E VAL+A EFW T+ Sbjct: 231 KNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEV 290 Query: 1043 -----------------------XXXXXXXXXXXGSDDANSTVNYRFIEKALPSLVPMLL 1153 D+ + RF K+ +P Sbjct: 291 LASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRF-HKSRTVTLPHEA 349 Query: 1154 ETLLKQEEDQEQDD----NAWNISMSGGTCLGLIARTVGDAIVPLVMPFVEANITKPDWR 1321 E E+ ++ DD + WN+ L ++A + ++P ++P ++ + P+W Sbjct: 350 ERPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWV 409 Query: 1322 CREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNTMNDPNSQVKDTTAWTLGRVFELLHS 1501 +E+ G+I +G ++ + P + + L+ ++D + V+ WTL R H Sbjct: 410 VKESGILVLGAIAEG-CMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSR---YAHW 465 Query: 1502 PCSTNPIISNANLPRIMAVLLESSKD-VPNVAEKVCGAIYFLAQGYEDAEPVSSLLTPYL 1678 S P + +L +M LL+ D V E C A L E + L PYL Sbjct: 466 VVSQPP---DMHLKPLMTELLKRILDGNKRVQEAACSAFATL------EEEACTELVPYL 516 Query: 1679 PNVIAALLTA 1708 ++ L+ A Sbjct: 517 SYILDTLVFA 526
>O14089:IMB2_SCHPO Importin subunit beta-2 - Schizosaccharomyces pombe (Fission yeast)| Length = 910 Score = 64.3 bits (155), Expect = 3e-09 Identities = 80/420 (19%), Positives = 166/420 (39%), Gaps = 14/420 (3%) Frame = +2 Query: 1151 LETLLKQEEDQEQDDNA---WNISMSGGTCLGLIARTVGDAIVPLVMPFVEANITKPDWR 1321 LE + +++ ++DD+A WN+ L +++ ++ +++P ++ ++T DW+ Sbjct: 370 LEDEDEDDDEFDEDDDAFMDWNLRKCSAAALDVLSSFWKQRLLEIILPHLKQSLTSEDWK 429 Query: 1322 CREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNTMNDPNSQVKDTTAWTLGRVFELLHS 1501 +EA A G+I +G ++ + + + L+ ++ V+ T WTLGR + S Sbjct: 430 VQEAGVLAVGAIAEG-CMDGMVQYLPELYPYFLSLLDSKKPLVRTITCWTLGR-YSKWAS 487 Query: 1502 PCSTNPIISNANLPRIMAVLLESSKDVPNVAEKVCGAIYFLAQGYEDAEPVSSLLTPYLP 1681 + +P + +L + V E C A L E L PYL Sbjct: 488 CLESEEDRQKYFVPLLQGLLRMVVDNNKKVQEAGCSAFAILE------EQAGPSLVPYLE 541 Query: 1682 NVIAALLTAADRSDMTHVRLRASAYEALNEIVRVSNIPETSSIIGQLLQEIMRRLNLTFD 1861 ++ L A + +V + A + L + V + I L+ ++++ ++ D Sbjct: 542 PILTNLAFAFQKYQRKNVLILYDAVQTLADY--VGSALNDKRYIELLITPLLQKWSMIPD 599 Query: 1862 HQIFSSGDKEKQSDLQALLCGVLQVIIQKLNSSDAKSIIAQTADQLMLLFLRVFACHSAT 2041 D L L V + A++ L+L A + T Sbjct: 600 -------DDPNLFPLFECLSSVAVALRDGFAPFAAETYARTFRILRNTLYLITTAQNDPT 652 Query: 2042 VH-----------EEAMLAIGALAYATGPDFEKYMPEFLKYLEAGLQNYEEYQVCSISVG 2188 V + I AL P + P + + ++ E +V + Sbjct: 653 VDVPDRDFLVTTLDLVSGIIQALGSQVSPLLAQADPPLGQIIGICAKD-EVPEVRQSAYA 711 Query: 2189 VVGDICRALEDKILPFCDGIMTVLLKDLSNSQLNRSVKPPIFSCFGDIALAIGENFEKYL 2368 ++GD+C D+I P+CD ++ +L + L+ S G++AL +G++ ++++ Sbjct: 712 LLGDMCMYCFDQIRPYCDALLVDMLPQMQLPLLHVSASNNAIWSAGEMALQLGKDMQQWV 771 Score = 40.0 bits (92), Expect = 0.059 Identities = 52/214 (24%), Positives = 84/214 (39%), Gaps = 6/214 (2%) Frame = +2 Query: 2012 LRVFACHSATVHEEAMLAIGALAYATGPDFEKYMPEFLKYLEAGLQNYEEYQVCSI--SV 2185 LR+ ++ V E A L GP Y+ L L Q Y+ V + +V Sbjct: 507 LRMVVDNNKKVQEAGCSAFAILEEQAGPSLVPYLEPILTNLAFAFQKYQRKNVLILYDAV 566 Query: 2186 GVVGD-ICRALEDKILPFCDGIMTVLLKDLSNSQLNRSVKPPIFSCFGDIALAIGENFEK 2362 + D + AL DK + + ++T LL+ S + P+F C +A+A+ + F Sbjct: 567 QTLADYVGSALNDK--RYIELLITPLLQKWSMIPDDDPNLFPLFECLSSVAVALRDGFAP 624 Query: 2363 YL--PYAMPM-LQGAAELLVVLDQNDEDMVDYGNQLRRGIFEAYSGILQGLKGAKAQLMI 2533 + YA + L+ QND + + SGI+Q L + L+ Sbjct: 625 FAAETYARTFRILRNTLYLITTAQNDPTVDVPDRDFLVTTLDLVSGIIQALGSQVSPLLA 684 Query: 2534 PYAGHLLQFTEAVYKDGSRDESVTKAAVAVLGDL 2635 L Q KD V ++A A+LGD+ Sbjct: 685 QADPPLGQIIGICAKD--EVPEVRQSAYALLGDM 716
>O00410:IMB3_HUMAN Importin beta-3 - Homo sapiens (Human)| Length = 1097 Score = 61.6 bits (148), Expect = 2e-08 Identities = 103/513 (20%), Positives = 214/513 (41%), Gaps = 17/513 (3%) Frame = +2 Query: 212 SPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGIILKNSLDAKDSA 391 SPD +R AE + Q+ FLL + N E+R++A ++L+ L SA Sbjct: 20 SPDNVVRKQAEETYENIPGQSKITFLLQA---IRNTTAAEEARQMAAVLLRRLLS---SA 73 Query: 392 RKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDA-RQTSSQVIAKIASIEIPR---REW 559 E+ + +L +++ IK LL+ + + R+ + A++A I +W Sbjct: 74 FDEV----YPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDEDGNNQW 129 Query: 560 QDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQ--VNAVLTAVVQGMNQ 733 + + L +++ L++A L ++ P Q Q ++ + +VQ M Sbjct: 130 PEGLKFLFDSVSSQNVG--LREAAL----HIFWNFPGIFGNQQQHYLDVIKRMLVQCMQD 183 Query: 734 TELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAFECLVA 913 E S +R + +A + E N A ++ + + + LV Sbjct: 184 QEHPS-IRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVE 242 Query: 914 IASTYYVHLDPYMQTIFNLTAN-----AVKGDEEPVALQAVEFWSTICXXXXXXXXXXXG 1078 IA T +L P+++ L+ ++ + +AL+ + S Sbjct: 243 IADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAA----------- 291 Query: 1079 SDDANSTVNYRFIEKALPSLVPMLLETLLKQEED-----QEQDDNAWNISMSGGTCLGLI 1243 A + + + +P ++ M+++ L+++ED + +DD+ + +++G + L + Sbjct: 292 ---AMLRKHTNIVAQTIPQMLAMMVD--LEEDEDWANADELEDDDFDSNAVAGESALDRM 346 Query: 1244 ARTVGDAIV-PLVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLL 1420 A +G +V P++ + + PDW+ R A A +I +G +++ ++ ++F+L Sbjct: 347 ACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEG-CHQQMEGILNEIVNFVL 405 Query: 1421 NTMNDPNSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLESSKDVPNVAEK 1600 + DP+ +V+ +G++ P +++A LL++ +D N + Sbjct: 406 LFLQDPHPRVRYAACNAVGQM------ATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQ 459 Query: 1601 VCGAIYFLAQGYEDAEPVSSLLTPYLPNVIAAL 1699 A L ED SLL PYL N++ L Sbjct: 460 AHAAA-ALINFTEDCP--KSLLIPYLDNLVKHL 489
>Q8BKC5:IMB3_MOUSE Importin beta-3 - Mus musculus (Mouse)| Length = 1097 Score = 59.3 bits (142), Expect = 9e-08 Identities = 105/513 (20%), Positives = 209/513 (40%), Gaps = 17/513 (3%) Frame = +2 Query: 212 SPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGIILKNSLDAKDSA 391 SPD +R AE + ++ FLL + N E+R++A ++L+ L SA Sbjct: 20 SPDNVVRKQAEETYENIPGRSKITFLLQA---IRNTTAAEEARQMAAVLLRRLLS---SA 73 Query: 392 RKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDA-RQTSSQVIAKIASIEIPR---REW 559 E+ + +L +++ IK LL+ + + R+ + A++A I +W Sbjct: 74 FDEV----YPALPSDVQTAIKSELLMIIQMETQSSMRKKICDIAAELARNLIDEDGNNQW 129 Query: 560 QDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQ--VNAVLTAVVQGMNQ 733 + + L +++ L++A L ++ P Q Q ++ + +VQ M Sbjct: 130 PEGLKFLFDSVSSQNMG--LREAAL----HIFWNFPGIFGNQQQHYLDVIKRMLVQCMQD 183 Query: 734 TELSSEVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAFECLVA 913 E S +R + +A + E N A ++ + + + LV Sbjct: 184 QEHPS-IRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVE 242 Query: 914 IASTYYVHLDPYMQTIFNLTANAVKGDEEPVALQ---AVEFWSTICXXXXXXXXXXXGSD 1084 IA T +L P+++ L+ GD +Q A+E T+ Sbjct: 243 IADTVPKYLRPHLEATLQLSLKLC-GDTNLNNMQRQLALEVIVTL--------------- 286 Query: 1085 DANSTVNYRFIEKALPSLVPMLLETLLKQEEDQE-------QDDNAWNISMSGGTCLGLI 1243 + R + +P +L ++ EED++ +DD+ + +++G + L + Sbjct: 287 SETAAAMLRKHTSLIAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRM 346 Query: 1244 ARTVGDAIV-PLVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLL 1420 A +G +V P++ + + PDW+ R A A +I +G +++ ++ ++F+L Sbjct: 347 ACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEG-CHQQMEGILNEIVNFVL 405 Query: 1421 NTMNDPNSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLESSKDVPNVAEK 1600 + DP+ +V+ +G++ P +++A LL++ +D N + Sbjct: 406 LFLQDPHPRVRYAACNAVGQM------ATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQ 459 Query: 1601 VCGAIYFLAQGYEDAEPVSSLLTPYLPNVIAAL 1699 A L ED SLL PYL N++ L Sbjct: 460 AHAAA-ALINFTEDCP--KSLLIPYLDNLVKHL 489
>P38217:IMB2_YEAST Importin subunit beta-2 - Saccharomyces cerevisiae (Baker's yeast)| Length = 918 Score = 58.2 bits (139), Expect = 2e-07 Identities = 126/659 (19%), Positives = 244/659 (37%), Gaps = 77/659 (11%) Frame = +2 Query: 176 VMDITQILLAAQSPDGNLRSAAEANIKQFQEQ-NLPNFLLSLSVELSNDERPPE------ 334 V+ + +L SP+ +R+ A ++ FQ Q N+L + +E +D+ + Sbjct: 12 VLQLATLLQNCMSPNPEIRNNAMEAMENFQLQPEFLNYLCYILIEGESDDVLKQHYSLQD 71 Query: 335 ---SRRLAGIILKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQT 505 +R AG++LKNS+ ++ K S H + +K +++ L +S + Sbjct: 72 LQNNRATAGMLLKNSMLGGNNLIK--------SNSHDL-GYVKSNIIHGLYNSNNNLVSN 122 Query: 506 SSQVIAKIASIEIPRREWQD--------LIAKLLSNMTQPGASAPLKQATLEALGYVCEE 661 + ++ R+ D + +L SN +P A K A + E Sbjct: 123 VTGIVITTLFSTYYRQHRDDPTGLQMLYQLLELTSNGNEPSIKALSKIMEDSAQFFQLEW 182 Query: 662 IPPEHLEQDQVNAVLTAVVQGMNQTELSSEVRLAAVKALYNALDFAESNFANEMERTFIM 841 + A+L + + ++ S +R +VK + + +F +++ + Sbjct: 183 SG----NTKPMEALLDSFFRFISNPNFSPVIRSESVKCINTVIPLQTQSFIVRLDK--FL 236 Query: 842 KVICDTAVSKEVEIRQA----AFECLVAIASTYYV-HLDPYMQTIFNLTANAVKGDEEPV 1006 ++I A + E ++ +A +F L+ V HLD +Q + +L +EE V Sbjct: 237 EIIFQLAQNDENDLVRAQICISFSFLLEFRPDKLVSHLDGIVQFMLHLITTV---NEEKV 293 Query: 1007 ALQAVEFWSTICXXXXXXXXXXXGSDDANSTVNYRFIEKALPSLVPMLLETLLKQEE--- 1177 A++A EF + + ++ + +VP+LL ++ EE Sbjct: 294 AIEACEFLHAFA---------------TSPNIPEHILQPYVKDIVPILLSKMVYNEESIV 338 Query: 1178 ---------------------------------------DQEQDDN-----------AWN 1207 D E DD+ WN Sbjct: 339 LLEASNDDDAFLEDKDEDIKPIAPRIVKKKEAGNGEDADDNEDDDDDDDDEDGDVDTQWN 398 Query: 1208 ISMSGGTCLGLIARTVGDAIVPLVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLA 1387 + L ++ + ++ + PF+ ++ W REA A G++ +G ++ Sbjct: 399 LRKCSAATLDVMTNILPHQVMDIAFPFLREHLGSDRWFIREATILALGAMAEG-GMKYFN 457 Query: 1388 PLVQAGLDFLLNTMNDPNSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLE 1567 + A + FL+ +ND + V+ T WTL R + + I L I+ L++ Sbjct: 458 DGLPALIPFLVEQLNDKWAPVRKMTCWTLSRFSPWILQDHTEFLI---PVLEPIINTLMD 514 Query: 1568 SSKDVPNVAEKVCGAIYFLAQGYEDAEPVSSLLTPYLPNVIAALLTAADRSDMTHVRLR- 1744 KDV A + F+ D+E V +L + LLT+ D+ + + Sbjct: 515 KKKDVQEAA--ISSVAVFIENA--DSELVETLF-------YSQLLTSFDKCLKYYKKKNL 563 Query: 1745 ASAYEALNEIVRVSNIPETSSIIGQLLQEIMRRLNLTFDHQIFSSGDKEKQSDLQALLC 1921 Y+A+ + ET+ I +L ++ + L S DKE L+ L C Sbjct: 564 IILYDAIGRFAEKCALDETAMQI--ILPPLIEKWAL------LSDSDKELWPLLECLSC 614
>O60100:IMB4_SCHPO Probable importin beta-4 subunit - Schizosaccharomyces pombe (Fission| yeast) Length = 1067 Score = 54.3 bits (129), Expect = 3e-06 Identities = 117/542 (21%), Positives = 224/542 (41%), Gaps = 22/542 (4%) Frame = +2 Query: 179 MDITQILLAAQSPDGN-LRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGI 355 +++TQ+L + +PD + A A ++ ++ P LLSL + E P + R+LA I Sbjct: 7 LELTQLLFQSIAPDTTQITEATRALETKYLKE--PGSLLSLFHIMGTCENP-QVRQLAAI 63 Query: 356 ILKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLL-ITLGSSVGDARQTSSQVIAKIA 532 ARK L + W S+D +++QI+ +LL ITL R +VIA +A Sbjct: 64 ----------EARK-LCHKYWSSVDADVQNQIRSNLLDITLKEPESIVRHAFGRVIAALA 112 Query: 533 SIEIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTA 712 +++P +W +L A L+ S +++ + L + E + D N +L Sbjct: 113 KLDLPEGKWNELSAFLVQATMDQNDS--IREMAVYVLYSIAETV-------DLDNKLLLD 163 Query: 713 VVQGMNQ--TELSSEVRLAAVKALYNALDFAESN-----FANEMERTFIMKVICDTAVSK 871 V +Q T+ S VR+ +V+ L + ES+ A ++ V+ D Sbjct: 164 FVNLFSQTITDSSRTVRVTSVQGLGAIAEVLESDDKKLLHAYRATLPGMLLVLQDVVQVG 223 Query: 872 EVEIRQAAFEC----LVAIASTYYVHLDPYMQTIFNLTANAVKGDEEPVALQAVEFWSTI 1039 +V+ + F+ L+A + L ++ I + AN+ + D+E + A+ F + Sbjct: 224 DVDASKQVFDVFNTFLIASGAIISKALGNIIEIITGI-ANSKQVDDE-IRCMALSFIISC 281 Query: 1040 CXXXXXXXXXXXGSDDANSTVNYRFIEKALPS------LVPMLLETLLKQEEDQEQDDNA 1201 RF + L + LV L+E ++ D +D Sbjct: 282 ----------------------IRFKSRKLQALKLGKPLVLTLMEVATEETTDDIDEDCP 319 Query: 1202 WNISMSGGTCLGLIARTVGDAIVPLVMPFVEANIT---KPDWRCREAATFAFGSILDGPS 1372 +++ + L++ + + V P EA P R+AA + G ++G S Sbjct: 320 ARLALRS---IDLLSTHLSPSQV--FYPMFEAACAFSQSPQASYRKAALLSIGVAVEGSS 374 Query: 1373 LEKLAPLVQAGLDFLLNTMNDPNSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIM 1552 E +A + ++N + D + V+ L ++ + + S + +A L ++ Sbjct: 375 -ESVAGNLPNIFPIIINGLCDNDMDVRQAALLALSQIAVEIPTEVSKH----HAQLLPLV 429 Query: 1553 AVLLESSKDVPNVAEKVCGAIYFLAQGYEDAEPVSSLLTPYLPNVIAALLTAADRSDMTH 1732 L+ S V + C I L +G + +E ++ YLP ++ L+ + SD Sbjct: 430 FELM--STQGVKVGKSACNCIDALLEGLDKSE-----ISGYLPMLMERLVGLLEFSDTPD 482 Query: 1733 VR 1738 ++ Sbjct: 483 IK 484
>Q8BIV3:RNBP6_MOUSE Ran-binding protein 6 - Mus musculus (Mouse)| Length = 1105 Score = 52.8 bits (125), Expect = 9e-06 Identities = 49/209 (23%), Positives = 93/209 (44%), Gaps = 11/209 (5%) Frame = +2 Query: 890 AAFECLVAIASTYYVHLDPYMQTIFNLTANAVKGDEEPVALQ---AVEFWSTICXXXXXX 1060 + E LV IA T +L PY++ L+ GD LQ A+E T+ Sbjct: 243 SVLESLVEIADTVPKYLGPYLEDTLQLSLKLC-GDSRLSNLQRQLALEVIVTL------- 294 Query: 1061 XXXXXGSDDANSTV--NYRFIEKALPSLVPMLLETLLKQEED------QEQDDNAWNISM 1216 S+ A + + I +A+P ++ M+++ L+ ++D E+DD N Sbjct: 295 ------SETATPMLKKHTNIIAQAVPHILAMMVD--LQDDDDWVNADEMEEDDFDSNAVA 346 Query: 1217 SGGTCLGLIARTVGDAIVPLVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLV 1396 + L G ++P+ + + PDW+CR A A +I +G +++ P++ Sbjct: 347 AESALDRLACGLGGKVVLPMTKEHIMQMLQSPDWKCRHAGLMALSAIGEG-CHQQMEPIL 405 Query: 1397 QAGLDFLLNTMNDPNSQVKDTTAWTLGRV 1483 ++ +L + DP+ +V+ TLG++ Sbjct: 406 DETVNSVLLFLQDPHPRVRAAACTTLGQM 434 Score = 35.4 bits (80), Expect = 1.4 Identities = 43/182 (23%), Positives = 86/182 (47%), Gaps = 20/182 (10%) Frame = +2 Query: 2093 PDFEKYMPEFLKYLEAGLQNYEEYQVCSISVGVVGDICRAL-EDKILPFCDGIMTVLLK- 2266 P ++ +MP +E +Q E + ++ + + A+ ++K + +M +LLK Sbjct: 537 PYYDIFMPSLKHVVELAVQK-ELKLLRGKTIECISHVGLAVGKEKFMQDASNVMQLLLKT 595 Query: 2267 --DLSNSQLNRSVKPPIFSCFGDIALAIGENFEKYLPYAM-PMLQGAAEL--LVVLDQND 2431 DL+N + + + S + + +G++FE+YLP + P+++ A+ + +LD D Sbjct: 596 QSDLNNMEDDDPQTSYMVSAWARMCKILGKDFEQYLPLVIEPLIKTASAKPDVALLDTQD 655 Query: 2432 ED---------MVDYGNQLRRGIFEAYSGILQGLKGAKAQLMIPYAGHL----LQFTEAV 2572 + V+ G+Q GI SG+ K Q+++ YA L +++TE V Sbjct: 656 VENMSDDDGWQFVNLGDQQSFGI--KTSGL--EAKATACQMLVYYAKELREGFVEYTEQV 711 Query: 2573 YK 2578 K Sbjct: 712 VK 713
>Q8VI75:IPO4_MOUSE Importin-4 - Mus musculus (Mouse)| Length = 1082 Score = 48.9 bits (115), Expect = 1e-04 Identities = 63/255 (24%), Positives = 100/255 (39%), Gaps = 21/255 (8%) Frame = +2 Query: 1136 LVPMLLETLLK-----------QEEDQEQDDNAWNISMSGGTCLGLIARTVG-------- 1258 LVP LL L EDQ+ DD+ I + G T + V Sbjct: 287 LVPPLLHALFPLMAAEPPMGQLDPEDQDSDDDDLEIGLMGETPKHFAVQVVDMLALHLPP 346 Query: 1259 DAIVPLVMPFVEANITKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNTMNDP 1438 + + P VMP +E + D R+A + DG L+ L + ++DP Sbjct: 347 EKLCPHVMPMLEEALRSEDPYQRKAGFLVLAVLSDGAGDHIRQRLLYPLLQIVCKGLDDP 406 Query: 1439 NSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLESSKDVP-NVAEKVCGAI 1615 + V++ + LG+ E L P IS+ + +M +LL K VP + A Sbjct: 407 SQIVRNAALFALGQFSENL------QPHISSYS-EEVMPLLLSYLKSVPMGNTHHLAKAC 459 Query: 1616 YFLAQGYEDAEPVSSLLTPYLPNVIAALLTAADRSDMTHVR-LRASAYEALNEIVRVSNI 1792 Y L E+ P + PYLP ++ +L + L SA A+ + S + Sbjct: 460 YALENFVENLGP---KVQPYLPELMECMLQPLKNPSKARTKELAVSAIGAIATAAQDSLL 516 Query: 1793 PETSSIIGQLLQEIM 1837 P +I+ LL+E + Sbjct: 517 PYFPTIM-DLLREFL 530 Score = 45.4 bits (106), Expect = 0.001 Identities = 40/168 (23%), Positives = 73/168 (43%), Gaps = 1/168 (0%) Frame = +2 Query: 1997 LMLLFLRVFACHSATVHEEAMLAIGALAYATGPDFEKYMPEFLKYLEAGLQNYEEYQVCS 2176 L+L +L+ + +A A+ GP + Y+PE ++ + L+N + + Sbjct: 439 LLLSYLKSVPMGNTHHLAKACYALENFVENLGPKVQPYLPELMECMLQPLKNPSKARTKE 498 Query: 2177 ISVGVVGDICRALEDKILPFCDGIMTVLLKDLSNSQLN-RSVKPPIFSCFGDIALAIGEN 2353 ++V +G I A +D +LP+ IM +L + L + V+ G +A A+GE+ Sbjct: 499 LAVSAIGAIATAAQDSLLPYFPTIMDLLREFLLTGHEDFHLVQIQSLETLGVLARALGES 558 Query: 2354 FEKYLPYAMPMLQGAAELLVVLDQNDEDMVDYGNQLRRGIFEAYSGIL 2497 + P A Q L + +D D Y +F A SG++ Sbjct: 559 MK---PLAEECCQLGLGLCIHIDDPDVRRCTY------SLFAALSGLM 597
>Q92616:GCN1L_HUMAN GCN1-like protein 1 - Homo sapiens (Human)| Length = 2671 Score = 47.8 bits (112), Expect = 3e-04 Identities = 99/463 (21%), Positives = 179/463 (38%), Gaps = 39/463 (8%) Frame = +2 Query: 449 IKESLLITLGSSVGDARQTSSQV---IAK-IASIEIPRREWQDLIAKLLSNMTQPGASAP 616 +++S+++ +GS ++ +V +AK IA++ P ++ Q+ +A L P Sbjct: 1315 VRQSVVVLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLP---------P 1365 Query: 617 LKQATLEALGYVCEEIPPEHLEQDQVNAV------LTAVVQGMNQTELSSEVRLAAVKAL 778 L A E G + + + + LE D+ L +V+G+ L + +AA L Sbjct: 1366 LVPAIKEDAGGMIQRLMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAA---L 1422 Query: 779 YNALDFAESNFANEMERTFIMKVICDTAVSKEVE--------------------IRQAAF 898 +A+ + NF F +++C T + K E +R+AA Sbjct: 1423 TDAIQ-DKKNFRRREGALFAFEMLC-TMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAAD 1480 Query: 899 ECLVAIASTYYVHLDPYMQTIFNLTANAVKGDEEPVALQAVE--FWSTICXXXXXXXXXX 1072 +C A+ S NL+A+ VK P L A+E W T Sbjct: 1481 DCAKAVMS--------------NLSAHGVKL-VLPSLLAALEEESWRT-----------K 1514 Query: 1073 XGSDDANSTVNY---RFIEKALPSLVPMLLETLLKQEEDQEQDDNAWNISMSGGTCLGLI 1243 GS + + Y + + LP++VP L E L D+ + +G L I Sbjct: 1515 AGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLT---------DSHVKVQKAGQQALRQI 1565 Query: 1244 ARTVGDAIVPLVMPFVEANITKPDWRCREAATFA----FGSILDGPSLEKLAPLVQAGLD 1411 + + + + P + +T P + ++ F +D PSL + P+VQ Sbjct: 1566 GSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIVQ---- 1621 Query: 1412 FLLNTMNDPNSQVKDTTAWTLGRVFELLHSPCSTNPIISNANLPRIMAVLLESSKDVPNV 1591 D ++ + A +G ++ L P + + P + A LL+ +V V Sbjct: 1622 ---RAFQDRSTDTRKMAAQIIGNMYSLTDQK-DLAPYLPSVT-PGLKASLLDPVPEVRTV 1676 Query: 1592 AEKVCGAIYFLAQGYEDAEPVSSLLTPYLPNVIAALLTAADRS 1720 + K GA + +G E L P+L + ++ DRS Sbjct: 1677 SAKALGA---MVKGM--GESCFEDLLPWLMETLTYEQSSVDRS 1714
>P40069:IMB4_YEAST Importin beta-4 subunit - Saccharomyces cerevisiae (Baker's yeast)| Length = 1113 Score = 42.7 bits (99), Expect = 0.009 Identities = 34/129 (26%), Positives = 62/129 (48%), Gaps = 1/129 (0%) Frame = +2 Query: 395 KELLIQQWVSLDHSIKSQIKESLLITLGSSVGD-ARQTSSQVIAKIASIEIPRREWQDLI 571 ++L+ + W ++D S ++ IK SLL T S + R ++++VIA I + E+ +W DL+ Sbjct: 64 RKLVSKHWNAIDESTRASIKTSLLQTAFSEPKENVRHSNARVIASIGTEELDGNKWPDLV 123 Query: 572 AKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTAVVQGMNQTELSSE 751 L+ T G +Q + L + E+ ++ L Q +N S E Sbjct: 124 PNLI--QTASGEDVQTRQTAIFILFSLLEDFTSS--LSGHIDDFLALFSQTINDPS-SLE 178 Query: 752 VRLAAVKAL 778 +R + +AL Sbjct: 179 IRSLSAQAL 187 Score = 34.7 bits (78), Expect = 2.5 Identities = 35/158 (22%), Positives = 69/158 (43%), Gaps = 10/158 (6%) Frame = +2 Query: 1964 AKSIIAQTADQLM-LLFLRVFACHSATVHEEAMLAIGALAYATGPDFEKYMPEFLKYLEA 2140 A IA+ D LM LF + + S+ + + AIG+ A+A G F Y + YLE Sbjct: 471 AYDAIAKYLDPLMNKLFYMLESNESSKLRCAVVSAIGSAAFAAGSAFIPYFKTSVHYLEK 530 Query: 2141 GLQN--------YEEYQVCSISVGVVGDICRAL-EDKILPFCDGIMTVLLKDLSNSQLNR 2293 +QN ++ ++ + + + + RA+ D F + ++ + + + Sbjct: 531 FIQNCSQIEGMSEDDIELRANTFENISTMARAVRSDAFAEFAEPLVNSAYEAIKTD--SA 588 Query: 2294 SVKPPIFSCFGDIALAIGENFEKYLPYAMPMLQGAAEL 2407 ++ ++ ++A GENF +L +P + EL Sbjct: 589 RLRESGYAFIANLAKVYGENFAPFLKTILPEIFKTLEL 626
>Q9Y7K2:TOR2_SCHPO Phosphatidylinositol 3-kinase tor2 - Schizosaccharomyces pombe| (Fission yeast) Length = 2337 Score = 40.8 bits (94), Expect = 0.034 Identities = 57/258 (22%), Positives = 107/258 (41%), Gaps = 14/258 (5%) Frame = +2 Query: 2021 FACHSATVHEEAMLAIGALAYATGPDFEKYMPEFLKYLEAGLQNY-EEYQVCSISVGVVG 2197 F H + + + + A A PD +++ +L L N ++ V ++ +G Sbjct: 261 FRDHKDLLIRKTVTELIATLAAYNPD--EFVSNYLHVCMLHLLNLLKKENVKMLAFATIG 318 Query: 2198 DICRALEDKILPFCDGIMTVLLKDLSNSQLNRSVKPP-IFSCFGDIALAIGENFEKY--- 2365 + A+ + I+P+ D I + + L N+S IF C +++A+G+ F Y Sbjct: 319 KVAVAITNSIIPYLDPICDSIKESLKIHIRNKSASDAAIFQCISLLSIALGQAFSNYAYD 378 Query: 2366 ---LPYAMPMLQGAAELLVVLDQNDEDMVDYGNQLRRGIFEAYSGILQGLKGAKAQLMIP 2536 L +A + + + L L N ++ ++ + + S IL G Sbjct: 379 LFDLIFASGLSEASYRALSDLAHNIPPLLPV---IQERLLDMLSKILSGRPFIPPGCPPQ 435 Query: 2537 YAGHLLQFTE-AVYKDGSRDESVTKAAVAVLGDLADTLGPISKDLFKSHLFHVEFLRECL 2713 Y L+ ++ A K G V A+ VLG+ F ++ + EF+++C+ Sbjct: 436 YVARSLKSSKSASLKTGFFPNDVYILALKVLGNFD----------FSGYILN-EFVKDCV 484 Query: 2714 -----DLDDEVRETASWT 2752 + D EVR+TAS T Sbjct: 485 VVYLENNDPEVRKTASIT 502
>Q8TEX9:IPO4_HUMAN Importin-4 - Homo sapiens (Human)| Length = 1081 Score = 40.8 bits (94), Expect = 0.034 Identities = 64/282 (22%), Positives = 121/282 (42%), Gaps = 32/282 (11%) Frame = +2 Query: 1169 QEEDQEQDDNAWNISM----SGGTCLGLIARTVGDAIVPLVMPFVEANITKPDWRCREA- 1333 +EE++E DD A +M +G L A GD+ P F+ + K C A Sbjct: 815 EEEEEEDDDQAEYDAMLLEHAGEAIPALAAAAGGDSFAPFFAGFLPLLVCKTKQGCTVAE 874 Query: 1334 ATFAFGSILDGPSLEKL----APLVQAGLDFLLNTMNDPNSQVKDTTAWTLGRVFELLHS 1501 +FA G++ + +++ L A V L LL+T + + +V+ + +G + E Sbjct: 875 KSFAVGTLAE--TIQGLGAASAQFVSRLLPVLLSTAQEADPEVRSNAIFGMGVLAEHGGH 932 Query: 1502 PCSTNPIISNANLPRIMAVL--LESSKDVPNVAEKVCGAIYFLAQGYEDAEPVSSLLTPY 1675 P + + P+++ +L L + + V + +CGA+ L +P Sbjct: 933 P-------AQEHFPKLLGLLFPLLARERHDRVRDNICGALARLLMASPTRKPE------- 978 Query: 1676 LPNVIAALLTAADRSD-----MTHVRLRASAYEA--------LNEIVRVSNI-------- 1792 P V+AALL A + +T RL + Y++ E++R+ ++ Sbjct: 979 -PQVLAALLHALPLKEDLEEWVTIGRLFSFLYQSSPDQVIDVAPELLRICSLILADNKIP 1037 Query: 1793 PETSSIIGQLLQEIMRRLNLTFDHQIFSSGDKEKQSDLQALL 1918 P+T + + LL + ++ +F + S +K +LQA+L Sbjct: 1038 PDTKAALLLLLTFLAKQHTDSFQAAL-GSLPVDKAQELQAVL 1078 Score = 37.4 bits (85), Expect = 0.38 Identities = 41/172 (23%), Positives = 74/172 (43%), Gaps = 5/172 (2%) Frame = +2 Query: 1997 LMLLFLRVFACHSATVHEEAMLAIGALAYATGPDFEKYMPEFLKYLEAGLQNYEEYQVCS 2176 L+L +L+ +A A+ GP + Y+PE ++ + L+N + Sbjct: 439 LLLAYLKSVPLGHTHHLAKACYALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRAKE 498 Query: 2177 ISVGVVGDICRALEDKILPFCDGIMTVLLKDLSNSQLN-RSVKPPIFSCFGDIALAIGEN 2353 ++V +G I A + +LP+ IM L + L + + + V+ G +A A+GE Sbjct: 499 LAVSALGAIATAAQASLLPYFPAIMEHLREFLLTGREDLQPVQIQSLETLGVLARAVGEP 558 Query: 2354 FEKYLPYAMPMLQGAAEL-LVVLDQNDEDMVDYGNQLRR---GIFEAYSGIL 2497 P+ + +L L + DQ D+ LRR +F A SG++ Sbjct: 559 MR-------PLAEECCQLGLGLCDQVDDP------DLRRCTYSLFAALSGLM 597
>P35169:TOR1_YEAST Serine/threonine-protein kinase TOR1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 2470 Score = 40.4 bits (93), Expect = 0.045 Identities = 24/90 (26%), Positives = 44/90 (48%) Frame = +2 Query: 2051 EAMLAIGALAYATGPDFEKYMPEFLKYLEAGLQNYEEYQVCSISVGVVGDICRALEDKIL 2230 + +++IG +AY GPD Y+ + L Y+E LQ +++ + E++I Sbjct: 407 QILISIGDIAYEVGPDIAPYVKQILDYIEHDLQTKFKFR-------------KKFENEIF 453 Query: 2231 PFCDGIMTVLLKDLSNSQLNRSVKPPIFSC 2320 +C G + V L + LNR++ +F C Sbjct: 454 -YCIGRLAVPLGPVLGKLLNRNILDLMFKC 482
>Q8K2V6:IPO11_MOUSE Importin-11 - Mus musculus (Mouse)| Length = 975 Score = 38.5 bits (88), Expect = 0.17 Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 5/141 (3%) Frame = +2 Query: 185 ITQILLAAQSPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGIILK 364 + Q+L A S D + AE +KQ++ Q P F L +N R LA + K Sbjct: 10 VLQVLTQATSQDTAVLKPAEEQLKQWETQ--PGFYSVLLNIFTNHTLDINVRWLAVLYFK 67 Query: 365 NSLDAKDSARKELLIQQWV-----SLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKI 529 + +D + W +L KS ++ L+ + + +IAK+ Sbjct: 68 HGID-----------RYWRRVAPHALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKV 116 Query: 530 ASIEIPRREWQDLIAKLLSNM 592 A ++ P R+W +LI L+ ++ Sbjct: 117 ARLDCP-RQWPELIPTLVESV 136
>Q9UI26:IPO11_HUMAN Importin-11 - Homo sapiens (Human)| Length = 975 Score = 37.7 bits (86), Expect = 0.29 Identities = 33/141 (23%), Positives = 60/141 (42%), Gaps = 5/141 (3%) Frame = +2 Query: 185 ITQILLAAQSPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGIILK 364 + Q+L A S D + AE +KQ++ Q P F L +N R LA + K Sbjct: 10 VLQVLTQATSQDTAVLKPAEEQLKQWETQ--PGFYSVLLNIFTNHTLDINVRWLAVLYFK 67 Query: 365 NSLDAKDSARKELLIQQWV-----SLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKI 529 + +D + W +L K+ ++ L+ + + +IAK+ Sbjct: 68 HGID-----------RYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKV 116 Query: 530 ASIEIPRREWQDLIAKLLSNM 592 A ++ P R+W +LI L+ ++ Sbjct: 117 ARLDCP-RQWPELIPTLIESV 136
>O74476:IMB3_SCHPO Importin beta-3 subunit - Schizosaccharomyces pombe (Fission yeast)| Length = 1095 Score = 37.4 bits (85), Expect = 0.38 Identities = 39/169 (23%), Positives = 77/169 (45%), Gaps = 2/169 (1%) Frame = +2 Query: 1889 EKQSDLQALLCGVLQVIIQKLNSSDAKSIIAQTADQLMLLFLRVFACHSATVHEEAMLAI 2068 +K S+ A L + + + A+ ++ + +++ + L + A V A A+ Sbjct: 383 QKWSERHAALMAISSI------AEGAEKLMKKELSRVLDMVLPLLADPHPRVRWAACNAV 436 Query: 2069 GALAYATGPDFE-KYMPEFLKYLEAGLQNYEEYQVCSISVGVVGDICRALEDKIL-PFCD 2242 G ++ PD + KY L+ L L++ E +V + + + + ++K+L P+ D Sbjct: 437 GQMSTDFAPDMQVKYPSRILEALVPVLESPES-RVQAHAAAAMVNFSEEADNKVLEPYLD 495 Query: 2243 GIMTVLLKDLSNSQLNRSVKPPIFSCFGDIALAIGENFEKYLPYAMPML 2389 I+ LL L + + R V+ + +A A + FEKY MP+L Sbjct: 496 DILQRLLTLLQSPK--RYVQEQAVTTIATVADAAAKKFEKYFDAIMPLL 542
>P53067:IMB5_YEAST Importin beta-5 subunit - Saccharomyces cerevisiae (Baker's yeast)| Length = 1004 Score = 36.6 bits (83), Expect = 0.65 Identities = 66/332 (19%), Positives = 138/332 (41%), Gaps = 44/332 (13%) Frame = +2 Query: 179 MDITQILLAAQSPDGNLRSAAEANIKQFQEQNLPNFLLSLSVELSNDERPPESRRLAGII 358 MDI ++++ AQS D + R AE + Q+ + + +L+ E ESR+ A + Sbjct: 1 MDINELIIGAQSADKHTREVAETQLLQWCDSDASQVFKALANVALQHEASLESRQFALLS 60 Query: 359 LKNSLDAKDSARKELLIQQWVSLDHSIKSQIKESLL-ITLGSSVG-DARQTSSQVIAKIA 532 L+ + S E + +++ +K I+E LL + L + + +S I +I+ Sbjct: 61 LRKLITMYWSPGFE-SYRSTSNVEIDVKDFIREVLLKLCLNDNENTKIKNGASYCIVQIS 119 Query: 533 SIEIPRREWQDLIAKLLSNMTQPGASAPLKQATLEALGYVCE----EIPPEHLEQDQVNA 700 +++ P +W L+ + ++ Q +L A+ + E + E + + Sbjct: 120 AVDFP-DQWPQLLTVIYDAISH--------QHSLNAMSLLNEIYDDVVSEEMFFEGGIGL 170 Query: 701 VLTAVVQGMNQTELSSEV-RLAAVKALYNA-LDFAESNFANEMER-TFIMKVIC------ 853 +V + TE S+ + ++AA+K L L + N +E R +F+ + + Sbjct: 171 ATMEIVFKVLNTETSTLIAKIAALKLLKACLLQMSSHNEYDEASRKSFVSQCLATSLQIL 230 Query: 854 ---------DTAVSKEVEIRQAAFECLVAIASTY-YVHLDPYMQTIF------------N 967 + V +++ + +E LV I + + H +Q F + Sbjct: 231 GQLLTLNFGNVDVISQLKFKSIIYENLVFIKNDFSRKHFSSELQKQFKIMAIQDLENVTH 290 Query: 968 LTANAVKGDEEPV-------ALQAVEFWSTIC 1042 + AN + EP+ ++ VEF +++C Sbjct: 291 INANVETTESEPLLETVHDCSIYIVEFLTSVC 322
>Q01441:GTR2_LEIDO Membrane transporter D2 - Leishmania donovani| Length = 558 Score = 36.6 bits (83), Expect = 0.65 Identities = 41/143 (28%), Positives = 58/143 (40%), Gaps = 10/143 (6%) Frame = -3 Query: 1611 APQTFSATFGTSLLLSSNTAMIRGRFAFDMIGLVL-----HGECKSSNTRPRVQAVVSFT 1447 AP + T GT +S +T G F GLVL + ++NT R+Q +VS + Sbjct: 234 APANHAKTLGTLFQVSVST----GIFVTSFFGLVLGNTIQYDAASNANTMGRMQGLVSVS 289 Query: 1446 WLFGSFIVLSKKSSPACTK-GASFSRDGPSRIEPNAKVAASRQRQSGFVMLAS----TNG 1282 L F+V P TK G S SR G E ASR+ + M NG Sbjct: 290 TLLSIFVVF----LPLITKDGYSKSRRGD--YEGENSEDASRKAAEEYTMTQMIGPILNG 343 Query: 1281 ITRGTIASPTVLAMSPRHVPPLM 1213 + G + T + + P +M Sbjct: 344 VAMGCVTQLTGINANMNFAPTIM 366
>P91349:SPD5_CAEEL Spindle-defective protein 5 - Caenorhabditis elegans| Length = 1198 Score = 35.4 bits (80), Expect = 1.4 Identities = 29/106 (27%), Positives = 47/106 (44%) Frame = +2 Query: 2417 LDQNDEDMVDYGNQLRRGIFEAYSGILQGLKGAKAQLMIPYAGHLLQFTEAVYKDGSRDE 2596 LD + D N R EA +G QG+ GA M+P + ++ G+ E Sbjct: 236 LDDQSARLADSENV--RAQLEAATG--QGILGAAGNAMVPNSTFMI---------GNGRE 282 Query: 2597 SVTKAAVAVLGDLADTLGPISKDLFKSHLFHVEFLRECLDLDDEVR 2734 S T+ + + DL L K+ K+ VE++ +C L+ E+R Sbjct: 283 SQTRDQLNYIDDLETKLADAKKENDKARQALVEYMNKCSKLEHEIR 328
>Q5UPK2:YL126_MIMIV Putative F-box protein L126 - Mimivirus| Length = 255 Score = 34.7 bits (78), Expect = 2.5 Identities = 17/40 (42%), Positives = 22/40 (55%) Frame = -1 Query: 2615 RRLLSRSHPCSHLCRQLQ*IAIDGLHKVSSAELLRPLDPV 2496 + L++ SH CSH C Q + I D L V AEL P P+ Sbjct: 17 KELIACSHACSHACSQWRRICSDKLLWVQKAELFGPESPI 56
>Q5R6J0:ECM29_PONPY Proteasome-associated protein ECM29 homolog - Pongo pygmaeus| (Orangutan) Length = 1810 Score = 34.7 bits (78), Expect = 2.5 Identities = 44/216 (20%), Positives = 85/216 (39%), Gaps = 5/216 (2%) Frame = +2 Query: 1127 LPSLVPMLLETLLKQEEDQEQD-DNAWNISMSGGTCLGLIARTVGDAIVPLVMPFVEANI 1303 LP LVP L Q + WN ++ +++ D + ++ + N+ Sbjct: 1085 LPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD--------KSMVDKYLKEILQDLVKNL 1136 Query: 1304 TKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNTMNDPNSQVKDTTAWTLGRV 1483 T WR RE++ A +L G L+ + + + L +D V+ L + Sbjct: 1137 TSNTWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETLFRVQDDIKESVRKAAELALKTL 1196 Query: 1484 FELLHSPCS-TNPIISNANLPRIMAVLLESSKDVPNVAEKVCGAIYFLAQGYEDAEPVSS 1660 ++ C + +++ LL+ P V E +I L + + A + Sbjct: 1197 SKVCVKMCDPAKGAAGQRTIAALLSCLLDKGMMSP-VTEVRALSINTLVKISKSA---GA 1252 Query: 1661 LLTPYLPNVIAAL---LTAADRSDMTHVRLRASAYE 1759 +L P+ P +I AL L+ + + ++ LRA+ E Sbjct: 1253 MLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQE 1288
>Q8NG31:CASC5_HUMAN Protein CASC5 - Homo sapiens (Human)| Length = 2342 Score = 34.3 bits (77), Expect = 3.2 Identities = 18/74 (24%), Positives = 42/74 (56%) Frame = +2 Query: 659 EIPPEHLEQDQVNAVLTAVVQGMNQTELSSEVRLAAVKALYNALDFAESNFANEMERTFI 838 EI H E+D + + +++ +++T S L ++KA +LDF+ +++ME F+ Sbjct: 1818 EIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYR-SSQMESQFL 1876 Query: 839 MKVICDTAVSKEVE 880 IC+ ++ ++++ Sbjct: 1877 RDTICEESLREKLQ 1890
>P08802:K118A_XENLA Keratin, type I cytoskeletal 18-A - Xenopus laevis (African clawed| frog) Length = 428 Score = 33.9 bits (76), Expect = 4.2 Identities = 35/168 (20%), Positives = 78/168 (46%), Gaps = 6/168 (3%) Frame = +2 Query: 419 VSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASIEIPRREWQDLIAKLLSNMTQ 598 ++L++ +S +KE L+ + D + +Q+ + ++E+ + QDL + Q Sbjct: 195 LNLENEFES-LKEELIFLKKNHQDDVNELQAQIASSAVTVEVDAPKSQDLGKIMADLRAQ 253 Query: 599 PGASAPLKQATLEAL--GYVCEEIPPEHLEQDQVNAVLTAVVQGMNQTELSSEVRLAAVK 772 A + +E L V E +L+ + ++ ++V + + +T S E+ L +++ Sbjct: 254 YDEMAQKNREDVEKLYQSKVEEHTVQVNLDAEALHTAKSSVTE-LRRTMQSLEIELESLR 312 Query: 773 ----ALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAFEC 904 +L L E+ +A E+E ++ TA++ E E+ Q +C Sbjct: 313 NQKASLEGTLHDTEARYAMELE------MLGGTAMALETELVQVRNDC 354
>P32898:CYM1_YEAST Mitochondrial presequence protease - Saccharomyces cerevisiae| (Baker's yeast) Length = 989 Score = 33.9 bits (76), Expect = 4.2 Identities = 43/204 (21%), Positives = 84/204 (41%) Frame = +2 Query: 389 ARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASIEIPRREWQDL 568 ARK+ L+ + +K I LL + + + +QT + + + P+ + Sbjct: 268 ARKDKLL-----MPIDLKKDIDVKLLGQIDTMLPPEKQTKASMTWICGA---PQDTYDTF 319 Query: 569 IAKLLSNMTQPGASAPLKQATLEALGYVCEEIPPEHLEQDQVNAVLTAVVQGMNQTELSS 748 + K+L N+ G S+ + Q +E+ G E +E +LT +QG++ E+ Sbjct: 320 LLKVLGNLLMDGHSSVMYQKLIES-GIGLEFSVNSGVEPTTAVNLLTVGIQGVSDIEIFK 378 Query: 749 EVRLAAVKALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAFECLVAIASTY 928 + V ++ L E F +R I +I +SK+ + + L +I + Sbjct: 379 DT----VNNIFQNLLETEHPF----DRKRIDAIIEQLELSKKDQKADFGLQLLYSILPGW 430 Query: 929 YVHLDPYMQTIFNLTANAVKGDEE 1000 +DP+ +F +GD E Sbjct: 431 TNKIDPFESLLFEDVLQRFRGDLE 454
>Q32PH7:SUV92_BOVIN Histone-lysine N-methyltransferase SUV39H2 - Bos taurus (Bovine)| Length = 410 Score = 33.5 bits (75), Expect = 5.5 Identities = 19/67 (28%), Positives = 34/67 (50%) Frame = +2 Query: 365 NSLDAKDSARKELLIQQWVSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASIEI 544 N+ + + + LL+QQ+ + H+ SQ+K+ ITL + + ++ I K A I Sbjct: 76 NTWEPLQNLKCPLLLQQFFNDKHNYLSQVKKGKAITLKENHRALKPAVAEYIVKKAKQRI 135 Query: 545 PRREWQD 565 + WQD Sbjct: 136 ALQRWQD 142
>Q6PDI5:ECM29_MOUSE Proteasome-associated protein ECM29 homolog - Mus musculus (Mouse)| Length = 1840 Score = 33.5 bits (75), Expect = 5.5 Identities = 48/218 (22%), Positives = 86/218 (39%), Gaps = 7/218 (3%) Frame = +2 Query: 1127 LPSLVPMLLETLLKQEEDQEQD-DNAWNISMSGGTCLGLIARTVGDAIVPLVMPFVEANI 1303 LP LVP L Q + WN ++ +++ D + ++ + N+ Sbjct: 1115 LPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD--------KSMVDKYLKEILQDLIKNL 1166 Query: 1304 TKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNTMNDPNSQVKDTTAWTLGRV 1483 T WR RE++ A +L G L+ + + + L +D V+ L + Sbjct: 1167 TSNMWRVRESSCLALNDLLRGRPLDDVIDKLPEMWETLFRVQDDIKESVRKAAELALKTL 1226 Query: 1484 FELLHSPCSTNPIISNANLPRIMAVLLESSKD---VPNVAEKVCGAIYFLAQGYEDAEPV 1654 ++ C A R +AVLL D + V E +I L + + A Sbjct: 1227 SKVCVKMCDP---AKGAAGQRTIAVLLPCLLDKGMMSPVTEVRALSINTLVKISKSA--- 1280 Query: 1655 SSLLTPYLPNVIAAL---LTAADRSDMTHVRLRASAYE 1759 ++L P+ P +I AL L+ + + ++ LRA+ E Sbjct: 1281 GAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQE 1318
>Q88A53:CCA_PSESM Multifunctional CCA protein [Includes: CCA-adding enzyme -| Pseudomonas syringae pv. tomato Length = 409 Score = 33.5 bits (75), Expect = 5.5 Identities = 18/62 (29%), Positives = 29/62 (46%) Frame = -1 Query: 2231 ARFYLPRHGKYHPPPLQRWSILGILHNSAILPQGTSKTQACISQNLGQWHKQEHQWPALL 2052 A F +P+ +HP +L +L SAI + AC+ +LG+ E +WP + Sbjct: 212 ALFGVPQPAAHHPEIDTGVHVLSVLEQSAIHKHPLTVRWACLLHDLGKGLTPESEWPRHI 271 Query: 2051 LH 2046 H Sbjct: 272 AH 273
>P32600:TOR2_YEAST Serine/threonine-protein kinase TOR2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 2474 Score = 33.1 bits (74), Expect = 7.2 Identities = 30/131 (22%), Positives = 56/131 (42%), Gaps = 8/131 (6%) Frame = +2 Query: 2057 MLAIGALAYATGPDFEKYMPEFLKYLEAGLQNYEEYQVCSISVGVVGDICRALEDKILPF 2236 +LA A T ++ M +L+YL+ N + +GDI + I P+ Sbjct: 376 LLAAFDPAIFTKKYLDRIMVHYLRYLKNIDMNAANNSDKPFILVSIGDIAFEVGSSISPY 435 Query: 2237 CDGIMTVLLKDLSNS-QLNRSVKPPIFSCFGDIALAIGENFEKYLPYAM-------PMLQ 2392 I+ + + L ++ + + +F C G +A A+G F K+L + PM Sbjct: 436 MTLILDNIREGLRTKFKVRKQFEKDLFYCIGKLACALGPAFAKHLNKDLLNLMLNCPMSD 495 Query: 2393 GAAELLVVLDQ 2425 E L++L++ Sbjct: 496 HMQETLMILNE 506
>Q6P864:K1C18_XENTR Keratin, type I cytoskeletal 18 - Xenopus tropicalis (Western| clawed frog) (Silurana tropicalis) Length = 429 Score = 33.1 bits (74), Expect = 7.2 Identities = 49/229 (21%), Positives = 102/229 (44%), Gaps = 12/229 (5%) Frame = +2 Query: 254 KQFQEQNLPNFLLSLSVELSNDERPPESRRL---AGIILKNSLDAKDSARKELLIQQWVS 424 KQ + L N L L ++ N + R+ A + ++ S++ + ++L+ VS Sbjct: 136 KQVFDSTLENSQLVLQID--NARLAADDFRVKYEAEMAIRMSVEGDITGLRKLIDDTNVS 193 Query: 425 ---LDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASIEIPRREWQDLIAKLLSNMT 595 L++ I+S +KE L+ + D + +QV ++E+ + QDL + Sbjct: 194 RMNLENEIES-LKEELIFLKKNHQDDVTELQAQVARSAVTVEVDAPKSQDLGKIMTELRA 252 Query: 596 QPGASAPLKQATLEA--LGYVCEEIPPEHLEQDQVNAVLTAVVQGMNQTELSSEVRLAAV 769 Q A + +E V E +L+ + +++ ++V + +T S E+ L ++ Sbjct: 253 QYDGLAQKNRDDVEKWYQSKVDEHTVQVNLDTEALHSAKSSVTD-LRRTVQSLEIELESL 311 Query: 770 K----ALYNALDFAESNFANEMERTFIMKVICDTAVSKEVEIRQAAFEC 904 + +L L E+ +A E+E ++ TA++ E E+ Q +C Sbjct: 312 RNQKASLEGTLHDTEARYAMELE------MLGGTAMAMEAELVQVRSDC 354
>Q5VYK3:ECM29_HUMAN Proteasome-associated protein ECM29 homolog - Homo sapiens (Human)| Length = 1845 Score = 33.1 bits (74), Expect = 7.2 Identities = 47/218 (21%), Positives = 85/218 (38%), Gaps = 7/218 (3%) Frame = +2 Query: 1127 LPSLVPMLLETLLKQEEDQEQD-DNAWNISMSGGTCLGLIARTVGDAIVPLVMPFVEANI 1303 LP LVP L Q + WN ++ +++ D + ++ + N+ Sbjct: 1120 LPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD--------KSMVDKYLKEILQDLVKNL 1171 Query: 1304 TKPDWRCREAATFAFGSILDGPSLEKLAPLVQAGLDFLLNTMNDPNSQVKDTTAWTLGRV 1483 T WR RE++ A +L G L+ + + + L +D V+ L + Sbjct: 1172 TSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETLFRVQDDIKESVRKAAELALKTL 1231 Query: 1484 FELLHSPCSTNPIISNANLPRIMAVLLESSKD---VPNVAEKVCGAIYFLAQGYEDAEPV 1654 ++ C A R +A LL D + V E +I L + + A Sbjct: 1232 SKVCVKMCDP---AKGAAGQRTIAALLPCLLDKGMMSTVTEVRALSINTLVKISKSA--- 1285 Query: 1655 SSLLTPYLPNVIAAL---LTAADRSDMTHVRLRASAYE 1759 ++L P+ P +I AL L+ + + ++ LRA+ E Sbjct: 1286 GAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQE 1323
>Q168K5:DTD_ROSDO D-tyrosyl-tRNA(Tyr) deacylase - Roseobacter denitrificans (strain| ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) Length = 148 Score = 33.1 bits (74), Expect = 7.2 Identities = 24/75 (32%), Positives = 41/75 (54%), Gaps = 1/75 (1%) Frame = +2 Query: 419 VSLDHSIKSQIKESLLITLGSSVGDARQTSSQVIAKIASIEIPRREWQDLIAKLLSNMTQ 598 V++D + I LLI + + GD + TS+++ AKI+ + R ++D K+ N+ Q Sbjct: 13 VAVDGNTIGAIDHGLLIFICAMPGDTKDTSARLAAKISRL----RVFKDDAGKMNLNLAQ 68 Query: 599 PGASA-PLKQATLEA 640 G +A + Q TL A Sbjct: 69 TGGAALVVSQFTLAA 83 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 531,797,687 Number of extensions: 11579152 Number of successful extensions: 33044 Number of sequences better than 10.0: 40 Number of HSP's gapped: 32950 Number of HSP's successfully gapped: 50 Length of query: 1018 Length of database: 100,686,439 Length adjustment: 123 Effective length of query: 895 Effective length of database: 66,948,154 Effective search space: 59918597830 Effective search space used: 59918597830 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
