ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf18f02 |
|---|---|
| Clone Library Name | barley_pub |
>P92937:CPK15_ARATH CBL-interacting serine/threonine-protein kinase 15 - Arabidopsis| thaliana (Mouse-ear cress) Length = 421 Score = 407 bits (1046), Expect = e-113 Identities = 214/434 (49%), Positives = 289/434 (66%) Frame = +2 Query: 464 MDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKRE 643 M+++ ++LM RYE+GK LGQGTFAKVY+AR+L TG +VAIK+I+K+++ KVG+ EQIKRE Sbjct: 1 MEKKGSVLMLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKRE 60 Query: 644 ISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLI 823 IS MRL++HPN+++L EVMATKSKIYFV+E+ KGGELFNK V GKL ED AR+YF QL+ Sbjct: 61 ISAMRLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFNK-VSTGKLREDVARKYFQQLV 119 Query: 824 SAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVA 1003 A+D+CHSRGV HR +SDFGLSAL+D RQDGLLHTTCGTPAYVA Sbjct: 120 RAVDFCHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVA 179 Query: 1004 PEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAEL 1183 PEV+SR GYDG KADVWS GVILFVL+AGYLPF ++NL+E+Y++I KA+ K P + + Sbjct: 180 PEVISRNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGA 239 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGCST 1363 K LL +ILDP+P+TR+ +I KS+W+R+ ++ K++ E T AEA + S + Sbjct: 240 KRLLKRILDPNPNTRVSTEKIMKSSWFRKGLQEEVKESVEEETEV-DAEAEGNAS---AE 295 Query: 1364 SERNQGSLSLPNLNAFDIIXXXXXXXXXXXXEDEYGRREERFTTRQPVTMVLTKFXXXXX 1543 E+ + NLNAF+II E + E RFT+ + + + K Sbjct: 296 KEKKR----CINLNAFEIISLSTGFDLSGLFEKGEEKEEMRFTSNREASEITEKLVEIGK 351 Query: 1544 XXXXXXXXXXXXXXXXAAPKEGKKGFLELDAEIFEVAPSFLLVELKKTNGDTMEYQKLVK 1723 + + ++AE+FE+APS+ +V LKK+ GDT EY++++K Sbjct: 352 DLKMKVRKKEHEWRVKMSAEA-----TVVEAEVFEIAPSYHMVVLKKSGGDTAEYKRVMK 406 Query: 1724 EEVRPALKDIVWVW 1765 E +RPAL D V W Sbjct: 407 ESIRPALIDFVLAW 420
>Q6X4A2:CIPK1_ORYSJ CIPK-like protein 1 - Oryza sativa subsp. japonica (Rice)| Length = 449 Score = 362 bits (929), Expect = 3e-99 Identities = 195/431 (45%), Positives = 271/431 (62%), Gaps = 2/431 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G+YE+G+ +G+GTFAKV +A+N + VAIK+++K+KV K L+EQI+REI M+LVK Sbjct: 17 VGKYELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVK 76 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPNV++LFEVM +K++I+ VLEY GGELF I G+L E+ AR+YF QLI+A+DYCHS Sbjct: 77 HPNVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHS 136 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 RGVYHR VSDFGLSAL + + DGLLHTTCGTP YVAPEV+ +G Sbjct: 137 RGVYHRDLKLENLLLDASGNLKVSDFGLSALTEQVKADGLLHTTCGTPNYVAPEVIEDRG 196 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDGA AD+WS GVIL+VL+AG+LPF + N+I +Y++IS+A F CP +FS K L+ +IL Sbjct: 197 YDGAAADIWSCGVILYVLLAGFLPFEDDNIIALYKKISEAQFTCPSWFSTGAKKLITRIL 256 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGCSTSERNQGSL 1387 DP+P+TRI IS+I + W+++ + + E T +AA S E + Sbjct: 257 DPNPTTRITISQILEDPWFKKGYKPPVFDEKYE-TSFDDVDAAFGDSEDRHVKEETEDQP 315 Query: 1388 SLPNLNAFDIIXXXXXXXXXXXXE--DEYGRREERFTTRQPVTMVLTKFXXXXXXXXXXX 1561 + ++NAF++I E EY +RE RFT++ P ++TK Sbjct: 316 T--SMNAFELISLNQALNLDNLFEAKKEY-KRETRFTSQCPPKEIITKIEEAAKPLGFDI 372 Query: 1562 XXXXXXXXXXAAPKEGKKGFLELDAEIFEVAPSFLLVELKKTNGDTMEYQKLVKEEVRPA 1741 K G+KG L + E+F+VAPS +VELKK GDT+E+QK + + Sbjct: 373 QKKNYKMRMENL-KAGRKGNLNVATEVFQVAPSLHVVELKKAKGDTLEFQKFYR-TLSTQ 430 Query: 1742 LKDIVWVWQGD 1774 LKD+VW G+ Sbjct: 431 LKDVVWKCDGE 441
>Q9LDI3:CPK24_ARATH CBL-interacting serine/threonine-protein kinase 24 - Arabidopsis| thaliana (Mouse-ear cress) Length = 446 Score = 331 bits (849), Expect = 7e-90 Identities = 183/433 (42%), Positives = 268/433 (61%), Gaps = 9/433 (2%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G+YE+G+ +G+GTFAKV +ARN TG VAIK++ K + K +++QIKREIS+M++V+ Sbjct: 8 VGKYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVR 67 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++L+EV+A+ SKIY VLE+ GGELF++IV +G+L E +R+YF QL+ A+ +CH Sbjct: 68 HPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHC 127 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG--LLHTTCGTPAYVAPEVLSR 1021 +GVYHR VSDFGLSAL Q+G LL TTCGTP YVAPEVLS Sbjct: 128 KGVYHRDLKPENLLLDTNGNLKVSDFGLSALP----QEGVELLRTTCGTPNYVAPEVLSG 183 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHK 1201 +GYDG+ AD+WS GVILFV++AGYLPF ET+L +YR+I+ A+F CP +FSAE+K L+H+ Sbjct: 184 QGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLIHR 243 Query: 1202 ILDPDPSTRIPISRIKKSAWYR-RPVEVNAKKTE----PEATHTFSAEAASSVSTGCSTS 1366 ILDP+P TRI I IKK W+R V + A++ E + F S V+ + Sbjct: 244 ILDPNPKTRIQIQGIKKDPWFRLNYVPIRAREEEEVNLDDIRAVFDGIEGSYVAE--NVE 301 Query: 1367 ERNQGSLSLPNLNAFDIIXXXXXXXXXXXXE--DEYGRREERFTTRQPVTMVLTKFXXXX 1540 ++G L +NAF++I + ++ +R+ RF +R+ + ++ Sbjct: 302 RNDEGPLM---MNAFEMITLSQGLNLSALFDRRQDFVKRQTRFVSRREPSEIIANIEAVA 358 Query: 1541 XXXXXXXXXXXXXXXXXAAPKEGKKGFLELDAEIFEVAPSFLLVELKKTNGDTMEYQKLV 1720 K G L + EI+EVAPS +V+++K G+T+EY K Sbjct: 359 NSMGFKSHTRNFKTRLEGL-SSIKAGQLAVVIEIYEVAPSLFMVDVRKAAGETLEYHKFY 417 Query: 1721 KEEVRPALKDIVW 1759 K ++ L++I+W Sbjct: 418 K-KLCSKLENIIW 429
>O22932:CPK11_ARATH CBL-interacting serine/threonine-protein kinase 11 - Arabidopsis| thaliana (Mouse-ear cress) Length = 435 Score = 319 bits (818), Expect = 3e-86 Identities = 163/306 (53%), Positives = 212/306 (69%), Gaps = 12/306 (3%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKV-TKVGLIEQIKREISVMRL 661 L G+YE+GK LG G FAKV++AR+ TGQ+VA+K++NK K+ T L IKREIS+MR Sbjct: 17 LFGKYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRR 76 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 + HPN+++L EVMATKSKI+F +E+ KGGELFNKI K G+L+ED +RRYF QLISA+ YC Sbjct: 77 LSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYC 136 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 H+RGVYHR VSDFGLSAL D R DGLLHT CGTPAYVAPE+LS+ Sbjct: 137 HARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSK 196 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHK 1201 KGY+GAK DVWS G++LFVLVAGYLPF++ N++ MY++I K +++ PR+ S +LK + + Sbjct: 197 KGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSR 256 Query: 1202 ILDPDPSTRIPISRIKKSAWYRR---------PVEVNAKKTEP--EATHTFSAEAASSVS 1348 +LD +P TRI I I K W+ R E+ +K E EA + +A S S Sbjct: 257 LLDINPETRITIDEILKDPWFVRGGFKQIKFHDDEIEDQKVESSLEAVKSLNAFDLISYS 316 Query: 1349 TGCSTS 1366 +G S Sbjct: 317 SGLDLS 322
>Q8RWC9:CIPK1_ARATH CBL-interacting serine/threonine-protein kinase 1 - Arabidopsis| thaliana (Mouse-ear cress) Length = 444 Score = 290 bits (741), Expect = 2e-77 Identities = 162/425 (38%), Positives = 241/425 (56%), Gaps = 3/425 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G+YE+G+ LG+G F KV +A++ +G + A+K+I+K ++ + QIKREI ++++K Sbjct: 17 LGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLK 76 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++++L EV+A+K+KI V+E GGELF++IV GKL E R+ F QLI I YCHS Sbjct: 77 HPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHS 136 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 +GV+HR ++DFGLSAL R DGLLHTTCG+P YVAPEVL+ +G Sbjct: 137 KGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRG 196 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDGA +D+WS GVIL+V++ G LPF + NL +Y++I K D PR+ S + ++ ++L Sbjct: 197 YDGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGARTMIKRML 256 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGCSTSERNQGSL 1387 DP+P TRI + IK S W++ + + E +A S G SE +GS Sbjct: 257 DPNPVTRITVVGIKASEWFKLEYIPSIPDDDDEEEVDTDDDAFSIQELG---SEEGKGSD 313 Query: 1388 SLPNLNAFDIIXXXXXXXXXXXXEDE-YGRREERFTTRQPVTMVLTKFXXXXXXXXXXXX 1564 S +NAF +I E E R RFT+ +L K Sbjct: 314 SPTIINAFQLIGMSSFLDLSGFFEQENVSERRIRFTSNSSAKDLLEKIETAVTEMGFSVQ 373 Query: 1565 XXXXXXXXXAAPK--EGKKGFLELDAEIFEVAPSFLLVELKKTNGDTMEYQKLVKEEVRP 1738 + +G+ G L + AE+FE+ PS +VEL+K+ GD+ Y++L + Sbjct: 374 KKHAKLRVKQEERNQKGQVG-LSVTAEVFEIKPSLNVVELRKSYGDSCLYRQLYER---- 428 Query: 1739 ALKDI 1753 LKD+ Sbjct: 429 LLKDV 433
>P92958:KIN11_ARATH SNF1-related protein kinase catalytic subunit alpha KIN11 -| Arabidopsis thaliana (Mouse-ear cress) Length = 512 Score = 220 bits (561), Expect = 2e-56 Identities = 106/261 (40%), Positives = 165/261 (63%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 ++ Y++GK LG G+F KV A ++ TG VAIK++N+ K+ + + E+++REI ++RL Sbjct: 16 ILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLF 75 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP++++ +EV+ T S IY V+EY K GELF+ IV++G+L ED AR +F Q+IS ++YCH Sbjct: 76 MHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCH 135 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 V HR ++DFGLS + R L T+CG+P Y APEV+S K Sbjct: 136 RNMVVHRDLKPENLLLDSRCNIKIADFGLS---NVMRDGHFLKTSCGSPNYAAPEVISGK 192 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + DVWS GVIL+ L+ G LPF + N+ ++++I + P + S+E +DL+ ++ Sbjct: 193 LYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRM 252 Query: 1205 LDPDPSTRIPISRIKKSAWYR 1267 L DP RI I I++ W++ Sbjct: 253 LIVDPVKRITIPEIRQHRWFQ 273
>Q38997:KIN10_ARATH SNF1-related protein kinase catalytic subunit alpha KIN10 -| Arabidopsis thaliana (Mouse-ear cress) Length = 535 Score = 213 bits (542), Expect = 3e-54 Identities = 101/261 (38%), Positives = 162/261 (62%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 ++ Y++G+ LG G+F +V A + TG VAIK++N+ K+ + + E+++REI ++RL Sbjct: 38 ILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLF 97 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP++++L+EV+ T + IY V+EY GELF+ IV++G+L ED AR +F Q+IS ++YCH Sbjct: 98 MHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCH 157 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 V HR ++DFGLS + R L T+CG+P Y APEV+S K Sbjct: 158 RNMVVHRDLKPENLLLDSKCNVKIADFGLS---NIMRDGHFLKTSCGSPNYAAPEVISGK 214 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + DVWS GVIL+ L+ G LPF + N+ ++++I + P + S +DL+ ++ Sbjct: 215 LYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRM 274 Query: 1205 LDPDPSTRIPISRIKKSAWYR 1267 L DP R+ I I++ W++ Sbjct: 275 LVVDPMKRVTIPEIRQHPWFQ 295
>O94168:SNF1_CANTR Carbon catabolite derepressing protein kinase - Candida tropicalis| (Yeast) Length = 619 Score = 212 bits (540), Expect = 4e-54 Identities = 108/262 (41%), Positives = 170/262 (64%), Gaps = 1/262 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +GRY+I K LG+G+F KV A+++ TGQ VA+K+IN+ + K + +++REIS +RL++ Sbjct: 49 IGRYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLR 108 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++++L++V+ +K +I V+E+A G ELF+ IV+ GK+ ED ARR+F Q+I+A++YCH Sbjct: 109 HPHIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHR 167 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLSRK 1024 + HR ++DFGLS + DG L T+CG+P Y APEV+S K Sbjct: 168 HKIVHRDLKPENLLLDDQLNVKIADFGLSNIMT----DGNFLKTSCGSPNYAAPEVISGK 223 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + DVWSSGVIL+V++ G LPF + + ++++IS + P Y S K LL ++ Sbjct: 224 LYAGPEVDVWSSGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSPGAKHLLTRM 283 Query: 1205 LDPDPSTRIPISRIKKSAWYRR 1270 L +P RI I I + W+++ Sbjct: 284 LVVNPLNRITIHEIMEDEWFKQ 305
>P52497:SNF1_CANAL Carbon catabolite derepressing protein kinase - Candida albicans| (Yeast) Length = 620 Score = 209 bits (533), Expect = 3e-53 Identities = 107/262 (40%), Positives = 170/262 (64%), Gaps = 1/262 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +GRY+I K LG+G+F KV A++L TGQ VA+K+IN+ + K + +++REIS +RL++ Sbjct: 50 IGRYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLR 109 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++++L++V+ +K +I V+E+A G ELF+ IV+ GK+ ED ARR+F Q+I+A++YCH Sbjct: 110 HPHIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHR 168 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYV-APEVLSRK 1024 + HR ++DFGLS + L T+CG+P Y+ APEV+S K Sbjct: 169 HKIVHRDLKPENLLLDDQLNVKIADFGLS---NIMTDGNFLKTSCGSPNYMPAPEVISGK 225 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + DVWS+GVIL+V++ G LPF + + ++++IS + P Y SA K LL ++ Sbjct: 226 LYAGPEVDVWSAGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSAGAKHLLTRM 285 Query: 1205 LDPDPSTRIPISRIKKSAWYRR 1270 L +P RI I I + W+++ Sbjct: 286 LVVNPLNRITIHEIMEDDWFKQ 307
>P54645:AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Rattus| norvegicus (Rat) Length = 548 Score = 208 bits (529), Expect = 8e-53 Identities = 103/286 (36%), Positives = 169/286 (59%), Gaps = 1/286 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 + +G Y +G LG GTF KV ++ TG VA+K++N+ K+ + ++ +I+REI ++L Sbjct: 11 VKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 70 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 +HP++++L++V++T S I+ V+EY GGELF+ I K G+L+E +RR F Q++S +DYC Sbjct: 71 FRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYC 130 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLS 1018 H V HR ++DFGLS + DG L T+CG+P Y APEV+S Sbjct: 131 HRHMVVHRDLKPENVLLDAHMNAKIADFGLSNM----MSDGEFLRTSCGSPNYAAPEVIS 186 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 + Y G + D+WSSGVIL+ L+ G LPF + ++ ++++I F P+Y + + LL Sbjct: 187 GRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLK 246 Query: 1199 KILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAA 1336 +L DP R I I++ W+++ + +P + T + A Sbjct: 247 HMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEA 292
>Q5RDH5:AAPK1_PONPY 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Pongo| pygmaeus (Orangutan) Length = 550 Score = 208 bits (529), Expect = 8e-53 Identities = 103/286 (36%), Positives = 169/286 (59%), Gaps = 1/286 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 + +G Y +G LG GTF KV ++ TG VA+K++N+ K+ + ++ +I+REI ++L Sbjct: 13 VRIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 72 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 +HP++++L++V++T S I+ V+EY GGELF+ I K G+L+E +RR F Q++S +DYC Sbjct: 73 FRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYC 132 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLS 1018 H V HR ++DFGLS + DG L T+CG+P Y APEV+S Sbjct: 133 HRHMVVHRDLKPENVLLDAHMNAKIADFGLSNM----MSDGEFLRTSCGSPNYAAPEVIS 188 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 + Y G + D+WSSGVIL+ L+ G LPF + ++ ++++I F P+Y + + LL Sbjct: 189 GRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLK 248 Query: 1199 KILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAA 1336 +L DP R I I++ W+++ + +P + T + A Sbjct: 249 HMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEA 294
>Q5EG47:AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Mus| musculus (Mouse) Length = 548 Score = 208 bits (529), Expect = 8e-53 Identities = 103/286 (36%), Positives = 169/286 (59%), Gaps = 1/286 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 + +G Y +G LG GTF KV ++ TG VA+K++N+ K+ + ++ +I+REI ++L Sbjct: 11 VKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 70 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 +HP++++L++V++T S I+ V+EY GGELF+ I K G+L+E +RR F Q++S +DYC Sbjct: 71 FRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYC 130 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLS 1018 H V HR ++DFGLS + DG L T+CG+P Y APEV+S Sbjct: 131 HRHMVVHRDLKPENVLLDAHMNAKIADFGLSNM----MSDGEFLRTSCGSPNYAAPEVIS 186 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 + Y G + D+WSSGVIL+ L+ G LPF + ++ ++++I F P+Y + + LL Sbjct: 187 GRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLK 246 Query: 1199 KILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAA 1336 +L DP R I I++ W+++ + +P + T + A Sbjct: 247 HMLQVDPMKRAAIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEA 292
>Q13131:AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Homo| sapiens (Human) Length = 550 Score = 208 bits (529), Expect = 8e-53 Identities = 103/286 (36%), Positives = 169/286 (59%), Gaps = 1/286 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 + +G Y +G LG GTF KV ++ TG VA+K++N+ K+ + ++ +I+REI ++L Sbjct: 13 VKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 72 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 +HP++++L++V++T S I+ V+EY GGELF+ I K G+L+E +RR F Q++S +DYC Sbjct: 73 FRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYC 132 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLS 1018 H V HR ++DFGLS + DG L T+CG+P Y APEV+S Sbjct: 133 HRHMVVHRDLKPENVLLDAHMNAKIADFGLSNM----MSDGEFLRTSCGSPNYAAPEVIS 188 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 + Y G + D+WSSGVIL+ L+ G LPF + ++ ++++I F P+Y + + LL Sbjct: 189 GRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLK 248 Query: 1199 KILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAA 1336 +L DP R I I++ W+++ + +P + T + A Sbjct: 249 HMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEA 294
>Q9P0L2:MARK1_HUMAN Serine/threonine-protein kinase MARK1 - Homo sapiens (Human)| Length = 795 Score = 206 bits (525), Expect = 2e-52 Identities = 109/303 (35%), Positives = 172/303 (56%), Gaps = 2/303 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K +G+G FAKV AR++ TG+ VA+K+I+K ++ L +++ RE+ +M+++ Sbjct: 57 IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSL-QKLFREVRIMKILN 115 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++LFEV+ T+ +Y V+EYA GGE+F+ +V G++ E AR F Q++SA+ YCH Sbjct: 116 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 175 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + + HR ++DFG S + L T CG+P Y APE+ K Sbjct: 176 KYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKK 232 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG + DVWS GVIL+ LV+G LPF NL E+ R+ + ++ P Y S + ++LL K+L Sbjct: 233 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLL 292 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKK--TEPEATHTFSAEAASSVSTGCSTSERNQG 1381 +P R + +I K W E K TEP+ + V+ G + E N Sbjct: 293 VLNPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDA 352 Query: 1382 SLS 1390 ++ Sbjct: 353 LIN 355
>O08678:MARK1_RAT Serine/threonine-protein kinase MARK1 - Rattus norvegicus (Rat)| Length = 793 Score = 206 bits (524), Expect = 3e-52 Identities = 110/303 (36%), Positives = 172/303 (56%), Gaps = 2/303 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K +G+G FAKV AR++ TG+ VA+K+I+K ++ L +++ RE+ +M+++ Sbjct: 57 IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSL-QKLFREVRIMKILN 115 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++LFEV+ T+ +Y V+EYA GGE+F+ +V G++ E AR F Q++SA+ YCH Sbjct: 116 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 175 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + + HR ++DFG S + L T CG+P Y APE+ K Sbjct: 176 KCIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKK 232 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG + DVWS GVIL+ LV+G LPF NL E+ R+ + ++ P Y S + ++LL K+L Sbjct: 233 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLL 292 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKK--TEPEATHTFSAEAASSVSTGCSTSERNQG 1381 +P R + +I K W E K +EPE + V+ G + E N Sbjct: 293 VLNPIKRGSLEQIMKDRWMNVGHEEEELKPYSEPELDLNDAKRIDIMVTMGFARDEINDA 352 Query: 1382 SLS 1390 +S Sbjct: 353 LVS 355
>Q8VHJ5:MARK1_MOUSE Serine/threonine-protein kinase MARK1 - Mus musculus (Mouse)| Length = 795 Score = 206 bits (524), Expect = 3e-52 Identities = 110/303 (36%), Positives = 172/303 (56%), Gaps = 2/303 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K +G+G FAKV AR++ TG+ VA+K+I+K ++ L +++ RE+ +M+++ Sbjct: 57 IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSL-QKLFREVRIMKILN 115 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++LFEV+ T+ +Y V+EYA GGE+F+ +V G++ E AR F Q++SA+ YCH Sbjct: 116 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 175 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + + HR ++DFG S + L T CG+P Y APE+ K Sbjct: 176 KCIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKK 232 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG + DVWS GVIL+ LV+G LPF NL E+ R+ + ++ P Y S + ++LL K+L Sbjct: 233 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLL 292 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKK--TEPEATHTFSAEAASSVSTGCSTSERNQG 1381 +P R + +I K W E K +EPE + V+ G + E N Sbjct: 293 VLNPIKRGSLEQIMKDRWMNVGHEEEELKPYSEPELDLNDAKRIDIMVTMGFARDEINDA 352 Query: 1382 SLS 1390 +S Sbjct: 353 LVS 355
>Q8TDC3:BRSK1_HUMAN BR serine/threonine-protein kinase 1 - Homo sapiens (Human)| Length = 794 Score = 206 bits (524), Expect = 3e-52 Identities = 97/264 (36%), Positives = 164/264 (62%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 R +G Y + K LG+G V + TGQ VAIK++N++K+++ ++ +++REI++ Sbjct: 42 RHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSE-SVLMKVEREIAI 100 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++L++HP+VL+L +V K +Y VLE+ GGELF+ +VK+G+L AR++F Q++SA+ Sbjct: 101 LKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSAL 160 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 D+CHS + HR ++DFG+++L D LL T+CG+P Y PEV Sbjct: 161 DFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEV 217 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + + YDG +AD+WS GVILF L+ G LPF + NL ++ ++ + F P + + + L Sbjct: 218 IKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSL 277 Query: 1193 LHKILDPDPSTRIPISRIKKSAWY 1264 L +++ +P R+ + +I+K WY Sbjct: 278 LRGMIEVEPEKRLSLEQIQKHPWY 301
>Q8CFH6:SN1L2_MOUSE Serine/threonine-protein kinase SNF1-like kinase 2 - Mus musculus| (Mouse) Length = 931 Score = 206 bits (523), Expect = 4e-52 Identities = 108/279 (38%), Positives = 165/279 (59%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 +R + +G Y+I LG+G FA V R+ T VAIK+I+K ++ V L E+I RE+ Sbjct: 11 QRGPVRVGFYDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQLDAVNL-EKIYREVQ 69 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 +M+++ HP++++L++VM TKS +Y V EYAK GE+F+ + G+LNE ARR F Q++SA Sbjct: 70 IMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSA 129 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 +DYCH R V HR ++DFG + + LL T CG+P Y APE Sbjct: 130 VDYCHGRKVVHRDLKAENLLLDNNMNIKIADFG---FGNFFKTGELLATWCGSPPYAAPE 186 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 V + Y+G + D+WS GV+L+VLV G LPF L + +R+ + F+ P + S + + Sbjct: 187 VFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEH 246 Query: 1190 LLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPE 1306 L+ ++L DPS R+ I++IK+ W V V P+ Sbjct: 247 LIRRMLVLDPSKRLSIAQIKEHKWMLIEVPVQRPILYPQ 285
>Q9H0K1:SN1L2_HUMAN Serine/threonine-protein kinase SNF1-like kinase 2 - Homo sapiens| (Human) Length = 926 Score = 206 bits (523), Expect = 4e-52 Identities = 107/279 (38%), Positives = 165/279 (59%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 +R + +G Y+I LG+G FA V R+ T VAIK+I+K ++ V L E+I RE+ Sbjct: 11 QRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNL-EKIYREVQ 69 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 +M+++ HP++++L++VM TKS +Y V EYAK GE+F+ + G+LNE ARR F Q++SA Sbjct: 70 IMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSA 129 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 +DYCH R + HR ++DFG + + LL T CG+P Y APE Sbjct: 130 VDYCHGRKIVHRDLKAENLLLDNNMNIKIADFG---FGNFFKSGELLATWCGSPPYAAPE 186 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 V + Y+G + D+WS GV+L+VLV G LPF L + +R+ + F+ P + S + + Sbjct: 187 VFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEH 246 Query: 1190 LLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPE 1306 L+ ++L DPS R+ I++IK+ W V V P+ Sbjct: 247 LIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQ 285
>Q00372:SNF1_CANGA Carbon catabolite derepressing protein kinase - Candida glabrata| (Yeast) (Torulopsis glabrata) Length = 612 Score = 205 bits (522), Expect = 5e-52 Identities = 105/261 (40%), Positives = 165/261 (63%), Gaps = 1/261 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y+I K LG+G+F KV A ++ TGQ VA+K+INK + K + +I+REIS +RL++ Sbjct: 36 VGNYQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR 95 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++++L++V+ +K +I V+EYA G ELF+ IV+ K++E ARR+F Q+ISA++YCH Sbjct: 96 HPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVEYCHR 154 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLSRK 1024 + HR ++DFGLS + DG L T+CG+P Y APEV+S K Sbjct: 155 HKIVHRDLKPENLLLDEHLNVKIADFGLSNIMT----DGNFLKTSCGSPNYAAPEVISGK 210 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + DVWS GVIL+V++ LPF + ++ +++ IS + P++ S DL+ ++ Sbjct: 211 LYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGASDLIKRM 270 Query: 1205 LDPDPSTRIPISRIKKSAWYR 1267 L +P RI I I + W++ Sbjct: 271 LIVNPLNRISIHEIMQDEWFK 291
>Q5RJI5:BRSK1_MOUSE BR serine/threonine-protein kinase 1 - Mus musculus (Mouse)| Length = 778 Score = 205 bits (522), Expect = 5e-52 Identities = 95/259 (36%), Positives = 163/259 (62%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K LG+G V + TGQ VA+K++N++K+++ ++ +++REI++++L++ Sbjct: 31 VGPYRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNREKLSE-SVLMKVEREIAILKLIE 89 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP+VL+L +V K +Y VLE+ GGELF+ +VK+G+L AR++F Q++SA+D+CHS Sbjct: 90 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHS 149 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + HR ++DFG+++L D LL T+CG+P Y PEV+ + Sbjct: 150 YSICHRDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIKGEK 206 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG +AD+WS GVILF L+ G LPF + NL ++ ++ + F P + + + LL ++ Sbjct: 207 YDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMI 266 Query: 1208 DPDPSTRIPISRIKKSAWY 1264 + +P R+ + +I+K WY Sbjct: 267 EVEPEKRLSLEQIQKHPWY 285
>Q69Z98:BRSK2_MOUSE BR serine/threonine-protein kinase 2 - Mus musculus (Mouse)| Length = 735 Score = 204 bits (519), Expect = 1e-51 Identities = 98/259 (37%), Positives = 161/259 (62%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K LG+G V + T Q VAIK++N++K+++ ++ +++REI++++L++ Sbjct: 17 VGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSE-SVLMKVEREIAILKLIE 75 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP+VL+L +V K +Y VLE+ GGELF+ +VK+G+L AR++F Q+ISA+D+CHS Sbjct: 76 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 135 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + HR ++DFG+++L D LL T+CG+P Y PEV+ + Sbjct: 136 HSICHRDLKPENLLLDERNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIRGEK 192 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG KADVWS GVILF L+ G LPF + NL ++ ++ + F P + + + LL ++ Sbjct: 193 YDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMI 252 Query: 1208 DPDPSTRIPISRIKKSAWY 1264 + D + R+ + I+K WY Sbjct: 253 EVDAARRLTLEHIQKHIWY 271
>Q8IWQ3:BRSK2_HUMAN BR serine/threonine-protein kinase 2 - Homo sapiens (Human)| Length = 736 Score = 204 bits (519), Expect = 1e-51 Identities = 98/259 (37%), Positives = 161/259 (62%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K LG+G V + T Q VAIK++N++K+++ ++ +++REI++++L++ Sbjct: 16 VGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSE-SVLMKVEREIAILKLIE 74 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP+VL+L +V K +Y VLE+ GGELF+ +VK+G+L AR++F Q+ISA+D+CHS Sbjct: 75 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + HR ++DFG+++L D LL T+CG+P Y PEV+ + Sbjct: 135 HSICHRDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIRGEK 191 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG KADVWS GVILF L+ G LPF + NL ++ ++ + F P + + + LL ++ Sbjct: 192 YDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMI 251 Query: 1208 DPDPSTRIPISRIKKSAWY 1264 + D + R+ + I+K WY Sbjct: 252 EVDAARRLTLEHIQKHIWY 270
>Q03141:MARK3_MOUSE MAP/microtubule affinity-regulating kinase 3 - Mus musculus (Mouse)| Length = 753 Score = 204 bits (518), Expect = 2e-51 Identities = 110/302 (36%), Positives = 170/302 (56%), Gaps = 1/302 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K +G+G FAKV AR++ TG+ VAIK+I+K ++ L +++ RE+ +M+++ Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSL-QKLFREVRIMKILN 111 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++LFEV+ T+ +Y ++EYA GGE+F+ +V G++ E AR F Q++SA+ YCH Sbjct: 112 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 171 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + + HR ++DFG S + L T CG+P Y APE+ K Sbjct: 172 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSK---LDTFCGSPPYAAPELFQGKK 228 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG + DVWS GVIL+ LV+G LPF NL E+ R+ + ++ P Y S + ++LL + L Sbjct: 229 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFL 288 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGCSTS-ERNQGS 1384 +P R + +I K W E + K E S + + G S E Q S Sbjct: 289 VLNPVKRGTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQES 348 Query: 1385 LS 1390 LS Sbjct: 349 LS 350
>O08679:MARK2_RAT Serine/threonine-protein kinase MARK2 - Rattus norvegicus (Rat)| Length = 722 Score = 204 bits (518), Expect = 2e-51 Identities = 101/258 (39%), Positives = 157/258 (60%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K +G+G FAKV AR++ TG+ VA+K+I+K ++ L +++ RE+ +M+++ Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL-QKLFREVRIMKVLN 108 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++LFEV+ T+ +Y V+EYA GGE+F+ +V G++ E AR F Q++SA+ YCH Sbjct: 109 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 168 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + + HR ++DFG S + L T CG+P Y APE+ K Sbjct: 169 KFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKK 225 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG + DVWS GVIL+ LV+G LPF NL E+ R+ + ++ P Y S + ++LL K L Sbjct: 226 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 285 Query: 1208 DPDPSTRIPISRIKKSAW 1261 +PS R + +I K W Sbjct: 286 ILNPSKRGTLEQIMKDRW 303
>Q7KZI7:MARK2_HUMAN Serine/threonine-protein kinase MARK2 - Homo sapiens (Human)| Length = 788 Score = 204 bits (518), Expect = 2e-51 Identities = 101/258 (39%), Positives = 157/258 (60%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K +G+G FAKV AR++ TG+ VA+K+I+K ++ L +++ RE+ +M+++ Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL-QKLFREVRIMKVLN 108 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++LFEV+ T+ +Y V+EYA GGE+F+ +V G++ E AR F Q++SA+ YCH Sbjct: 109 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 168 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + + HR ++DFG S + L T CG+P Y APE+ K Sbjct: 169 KFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKK 225 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG + DVWS GVIL+ LV+G LPF NL E+ R+ + ++ P Y S + ++LL K L Sbjct: 226 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 285 Query: 1208 DPDPSTRIPISRIKKSAW 1261 +PS R + +I K W Sbjct: 286 ILNPSKRGTLEQIMKDRW 303
>Q8VHF0:MARK3_RAT MAP/microtubule affinity-regulating kinase 3 - Rattus norvegicus| (Rat) Length = 797 Score = 203 bits (517), Expect = 2e-51 Identities = 110/302 (36%), Positives = 169/302 (55%), Gaps = 1/302 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K +G+G FAKV AR++ TG+ VAIK+I+K ++ L +++ RE+ +M+++ Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSL-QKLFREVRIMKILN 111 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++LFEV+ T+ +Y ++EYA GGE+F+ +V G++ E AR F Q++SA+ YCH Sbjct: 112 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 171 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + + HR ++DFG S + L T CG+P Y APE+ K Sbjct: 172 KRIVHRDLKAENLLLDADMNIKITDFGFSNEFTVGSK---LDTFCGSPPYAAPELFQGKK 228 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG + DVWS GVIL+ LV+G LPF NL E+ R+ + ++ P Y S + ++LL + L Sbjct: 229 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFL 288 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGCSTS-ERNQGS 1384 +P R + +I K W E K E S + + G S E Q S Sbjct: 289 VLNPVKRGTLEQIMKDRWINAGHEEEELKPFVEPELDISDQKRIDIMVGMGYSQEEIQES 348 Query: 1385 LS 1390 LS Sbjct: 349 LS 350
>Q09137:AAPK2_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Rattus| norvegicus (Rat) Length = 552 Score = 203 bits (517), Expect = 2e-51 Identities = 99/264 (37%), Positives = 158/264 (59%), Gaps = 1/264 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 + +G Y +G LG GTF KV + TG VA+K++N+ K+ + ++ +IKREI ++L Sbjct: 11 VKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 +HP++++L++V++T + + V+EY GGELF+ I K G++ E ARR F Q++SA+DYC Sbjct: 71 FRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYC 130 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLS 1018 H V HR ++DFGLS + DG L T+CG+P Y APEV+S Sbjct: 131 HRHMVVHRDLKPENVLLDAQMNAKIADFGLSNM----MSDGEFLRTSCGSPNYAAPEVIS 186 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 + Y G + D+WS GVIL+ L+ G LPF + ++ ++++I F P Y + + LL Sbjct: 187 GRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLM 246 Query: 1199 KILDPDPSTRIPISRIKKSAWYRR 1270 +L DP R I I++ W+++ Sbjct: 247 HMLQVDPLKRATIKDIREHEWFKQ 270
>Q5RD00:AAPK2_PONPY 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Pongo| pygmaeus (Orangutan) Length = 552 Score = 203 bits (516), Expect = 3e-51 Identities = 99/264 (37%), Positives = 158/264 (59%), Gaps = 1/264 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 + +G Y +G LG GTF KV + TG VA+K++N+ K+ + ++ +IKREI ++L Sbjct: 11 VKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 +HP++++L++V++T + + V+EY GGELF+ I K G++ E ARR F Q++SA+DYC Sbjct: 71 FRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLS 1018 H V HR ++DFGLS + DG L T+CG+P Y APEV+S Sbjct: 131 HRHMVVHRDLKPENVLLDAHMNAKIADFGLSNI----MSDGEFLRTSCGSPNYAAPEVIS 186 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 + Y G + D+WS GVIL+ L+ G LPF + ++ ++++I F P Y + + LL Sbjct: 187 GRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLM 246 Query: 1199 KILDPDPSTRIPISRIKKSAWYRR 1270 +L DP R I I++ W+++ Sbjct: 247 HMLQVDPLKRATIKDIREHEWFKQ 270
>Q28948:AAPK2_PIG 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Sus| scrofa (Pig) Length = 552 Score = 203 bits (516), Expect = 3e-51 Identities = 99/264 (37%), Positives = 158/264 (59%), Gaps = 1/264 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 + +G Y +G LG GTF KV + TG VA+K++N+ K+ + ++ +IKREI ++L Sbjct: 11 VKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 +HP++++L++V++T + + V+EY GGELF+ I K G++ E ARR F Q++SA+DYC Sbjct: 71 FRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLS 1018 H V HR ++DFGLS + DG L T+CG+P Y APEV+S Sbjct: 131 HRHMVVHRDLKPENVLLDAQMNAKIADFGLSNM----MSDGEFLRTSCGSPNYAAPEVIS 186 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 + Y G + D+WS GVIL+ L+ G LPF + ++ ++++I F P Y + + LL Sbjct: 187 GRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLM 246 Query: 1199 KILDPDPSTRIPISRIKKSAWYRR 1270 +L DP R I I++ W+++ Sbjct: 247 HMLQVDPLKRATIKDIREHEWFKQ 270
>P54646:AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Homo| sapiens (Human) Length = 552 Score = 203 bits (516), Expect = 3e-51 Identities = 99/264 (37%), Positives = 158/264 (59%), Gaps = 1/264 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 + +G Y +G LG GTF KV + TG VA+K++N+ K+ + ++ +IKREI ++L Sbjct: 11 VKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 +HP++++L++V++T + + V+EY GGELF+ I K G++ E ARR F Q++SA+DYC Sbjct: 71 FRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLS 1018 H V HR ++DFGLS + DG L T+CG+P Y APEV+S Sbjct: 131 HRHMVVHRDLKPENVLLDAHMNAKIADFGLSNM----MSDGEFLRTSCGSPNYAAPEVIS 186 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 + Y G + D+WS GVIL+ L+ G LPF + ++ ++++I F P Y + + LL Sbjct: 187 GRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLM 246 Query: 1199 KILDPDPSTRIPISRIKKSAWYRR 1270 +L DP R I I++ W+++ Sbjct: 247 HMLQVDPLKRATIKDIREHEWFKQ 270
>Q8BRK8:AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Mus| musculus (Mouse) Length = 552 Score = 202 bits (514), Expect = 5e-51 Identities = 99/264 (37%), Positives = 158/264 (59%), Gaps = 1/264 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 + +G Y +G LG GTF KV + TG VA+K++N+ K+ + ++ +IKREI ++L Sbjct: 11 VKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 +HP++++L++V++T + + V+EY GGELF+ I K G++ E ARR F Q++SA+DYC Sbjct: 71 FRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYC 130 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLS 1018 H V HR ++DFGLS + DG L T+CG+P Y APEV+S Sbjct: 131 HRHMVVHRDLKPENVLLDAQMNAKIADFGLSNM----MSDGEFLRTSCGSPNYAAPEVIS 186 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 + Y G + D+WS GVIL+ L+ G LPF + ++ ++++I F P Y + + LL Sbjct: 187 GRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPDYLNRSVATLLM 246 Query: 1199 KILDPDPSTRIPISRIKKSAWYRR 1270 +L DP R I I++ W+++ Sbjct: 247 HMLQVDPLKRATIKDIREHEWFKQ 270
>P06782:SNF1_YEAST Carbon catabolite derepressing protein kinase - Saccharomyces| cerevisiae (Baker's yeast) Length = 633 Score = 201 bits (510), Expect = 1e-50 Identities = 104/261 (39%), Positives = 163/261 (62%), Gaps = 1/261 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y+I K LG+G+F KV A + TGQ VA+K+INK + K + +I+REIS +RL++ Sbjct: 52 IGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR 111 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++++L++V+ +K +I V+EYA G ELF+ IV+ K++E ARR+F Q+ISA++YCH Sbjct: 112 HPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHR 170 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLSRK 1024 + HR ++DFGLS + DG L T+CG+P Y APEV+S K Sbjct: 171 HKIVHRDLKPENLLLDEHLNVKIADFGLSNIMT----DGNFLKTSCGSPNYAAPEVISGK 226 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + DVWS GVIL+V++ LPF + ++ +++ IS + P++ S L+ ++ Sbjct: 227 LYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRM 286 Query: 1205 LDPDPSTRIPISRIKKSAWYR 1267 L +P RI I I + W++ Sbjct: 287 LIVNPLNRISIHEIMQDDWFK 307
>Q05512:MARK2_MOUSE Serine/threonine-protein kinase MARK2 - Mus musculus (Mouse)| Length = 776 Score = 201 bits (510), Expect = 1e-50 Identities = 100/258 (38%), Positives = 156/258 (60%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K +G+G FAKV AR++ TG+ VA+K+I+K ++ L +++ RE+ +M+++ Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL-QKLFREVRIMKVLN 108 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++LFEV+ T+ +Y V+EYA GGE+F+ +V G++ E AR F Q++SA+ YCH Sbjct: 109 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 168 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + + HR ++DFG S + L T CG+P Y APE+ K Sbjct: 169 KFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKK 225 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 DG + DVWS GVIL+ LV+G LPF NL E+ R+ + ++ P Y S + ++LL K L Sbjct: 226 IDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 285 Query: 1208 DPDPSTRIPISRIKKSAW 1261 +PS R + +I K W Sbjct: 286 ILNPSKRGTLEQIMKDRW 303
>Q9IA88:SN1L2_CHICK Serine/threonine-protein kinase SNF1-like kinase 2 - Gallus gallus| (Chicken) Length = 798 Score = 199 bits (507), Expect = 3e-50 Identities = 102/262 (38%), Positives = 156/262 (59%) Frame = +2 Query: 476 RTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVM 655 R + +G Y+I + LG+G FA V AR+ T VAIK+I+K ++ L E+I RE+ +M Sbjct: 19 RPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDPSNL-EKIYREVQIM 77 Query: 656 RLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAID 835 +L+ HP++++L++VM TK +Y V E+AK GE+F+ + G L+E AR+ F Q++SA++ Sbjct: 78 KLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVE 137 Query: 836 YCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVL 1015 YCHS + HR ++DFG L T CG+P Y APEV Sbjct: 138 YCHSHHIVHRDLKTENLLLDANMNIKLADFGFGNFYKSGEP---LSTWCGSPPYAAPEVF 194 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLL 1195 K Y+G D+WS GV+L+VLV G LPF NL + +R+ + F+ P + S + + L+ Sbjct: 195 EGKEYEGPHLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEDCETLI 254 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 ++L DP+ RI IS+IK+ W Sbjct: 255 RRMLVVDPTKRITISQIKQHKW 276
>Q5REX1:SN1L2_PONPY Serine/threonine-protein kinase SNF1-like kinase 2 - Pongo pygmaeus| (Orangutan) Length = 925 Score = 199 bits (506), Expect = 4e-50 Identities = 105/279 (37%), Positives = 164/279 (58%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 +R + +G Y+I LG+G FA V R+ T VAIK+I+K ++ V L E+I RE+ Sbjct: 11 QRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNL-EKIYREVQ 69 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 +M+++ HP++++L++VM TKS +Y V EYAK GE+F+ + G+LNE ARR F Q++SA Sbjct: 70 IMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSA 129 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 +DYCH R + HR ++DF + + + LL T G+P Y APE Sbjct: 130 VDYCHGRKIVHRDLKAENLLLDNNMNIKIADF---SFGNFFKSGELLATWRGSPPYAAPE 186 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 V + Y+G + D+WS GV+L+VLV G LPF L + +R+ + F+ P + S + + Sbjct: 187 VFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEH 246 Query: 1190 LLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPE 1306 L+ ++L DPS R+ I++IK+ W V V P+ Sbjct: 247 LIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQ 285
>Q8CIP4:MARK4_MOUSE MAP/microtubule affinity-regulating kinase 4 - Mus musculus (Mouse)| Length = 752 Score = 199 bits (506), Expect = 4e-50 Identities = 102/275 (37%), Positives = 160/275 (58%), Gaps = 2/275 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + + +G+G FAKV AR++ TG+ VAIK+I+K ++ L +++ RE+ +M+ + Sbjct: 56 VGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSL-QKLFREVRIMKGLN 114 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++LFEV+ T+ +Y V+EYA GE+F+ +V G++ E AR F Q++SA+ YCH Sbjct: 115 HPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQ 174 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + + HR ++DFG S + L T CG+P Y APE+ K Sbjct: 175 KNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKK 231 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG + D+WS GVIL+ LV+G LPF NL E+ R+ + ++ P Y S + + +L + L Sbjct: 232 YDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFL 291 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKK--TEPE 1306 +P+ R + +I K W E K TEPE Sbjct: 292 VLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPE 326
>Q96L34:MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 - Homo sapiens (Human)| Length = 752 Score = 199 bits (506), Expect = 4e-50 Identities = 102/275 (37%), Positives = 160/275 (58%), Gaps = 2/275 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + + +G+G FAKV AR++ TG+ VAIK+I+K ++ L +++ RE+ +M+ + Sbjct: 56 VGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSL-QKLFREVRIMKGLN 114 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++LFEV+ T+ +Y V+EYA GE+F+ +V G++ E AR F Q++SA+ YCH Sbjct: 115 HPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQ 174 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + + HR ++DFG S + L T CG+P Y APE+ K Sbjct: 175 KNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKK 231 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG + D+WS GVIL+ LV+G LPF NL E+ R+ + ++ P Y S + + +L + L Sbjct: 232 YDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFL 291 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKK--TEPE 1306 +P+ R + +I K W E K TEPE Sbjct: 292 VLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPE 326
>Q95ZQ4:AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-2 -| Caenorhabditis elegans Length = 626 Score = 198 bits (503), Expect = 9e-50 Identities = 100/264 (37%), Positives = 156/264 (59%), Gaps = 1/264 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 I +G Y + + LG GTF KV + T VA+K++N+ K+ + ++ +I+REI + L Sbjct: 82 IKIGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSL 141 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 +HP++++L++V++T S I+ ++E+ GGELF+ IVK G+L ARR+F Q+IS +DYC Sbjct: 142 FRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYC 201 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLS 1018 H V HR ++DFGLS + DG L T+CG+P Y APEV+S Sbjct: 202 HRHMVVHRDLKPENLLLDEQNNVKIADFGLSNI----MTDGDFLRTSCGSPNYAAPEVIS 257 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 K Y G + DVWS GVIL+ L+ G LPF + ++ ++R+I F P + + +LLH Sbjct: 258 GKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLH 317 Query: 1199 KILDPDPSTRIPISRIKKSAWYRR 1270 +L DP R I + W+++ Sbjct: 318 HMLCVDPMKRATIKDVIAHEWFQK 341
>P57059:SN1L1_HUMAN Serine/threonine-protein kinase SNF1-like kinase 1 - Homo sapiens| (Human) Length = 783 Score = 197 bits (502), Expect = 1e-49 Identities = 99/266 (37%), Positives = 160/266 (60%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 +++ + +G Y+I + LG+G FA V AR+ T VAIK+I+K ++ L E+I RE+ Sbjct: 18 QQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNL-EKIYREVQ 76 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 +M+L+ HP++++L++VM TK +Y V E+AK GE+F+ + G L+E+ AR+ F Q++SA Sbjct: 77 LMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSA 136 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 ++YCH + HR ++DFG L T CG+P Y APE Sbjct: 137 VEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEP---LSTWCGSPPYAAPE 193 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 V K Y+G + D+WS GV+L+VLV G LPF NL + +R+ + F+ P + S + + Sbjct: 194 VFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCES 253 Query: 1190 LLHKILDPDPSTRIPISRIKKSAWYR 1267 L+ ++L DP+ RI I++I++ W R Sbjct: 254 LIRRMLVVDPARRITIAQIRQHRWMR 279
>Q9R1U5:SN1L1_RAT Serine/threonine-protein kinase SNF1-like kinase 1 - Rattus| norvegicus (Rat) Length = 776 Score = 197 bits (501), Expect = 1e-49 Identities = 98/264 (37%), Positives = 162/264 (61%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 +++ + +G Y++ + LG+G FA V AR+ T VAIK+I+K ++ L E+I RE+ Sbjct: 18 QQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNL-EKIYREVQ 76 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 +M+L+ HPN+++L++VM TK +Y V E+AK GE+F+ + G L+E+ AR+ F Q++SA Sbjct: 77 LMKLLNHPNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSA 136 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 ++YCH+ + HR ++DFG + + L T CG+P Y APE Sbjct: 137 VEYCHNHHIVHRDLKTENLLLDGNMDIKLADFG---FGNFYKPGEPLSTWCGSPPYAAPE 193 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 V K Y+G + D+WS GV+L+VLV G LPF NL + +R+ + F+ P + S + + Sbjct: 194 VFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCET 253 Query: 1190 LLHKILDPDPSTRIPISRIKKSAW 1261 L+ ++L DP+ RI I++I++ W Sbjct: 254 LIRRMLVVDPAKRITIAQIRQHRW 277
>Q9Y2K2:QSK_HUMAN Serine/threonine-protein kinase QSK - Homo sapiens (Human)| Length = 1263 Score = 196 bits (497), Expect = 4e-49 Identities = 100/260 (38%), Positives = 156/260 (60%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G YEI + +G+G FA V A +L T VAIK+I+K ++ + L ++I RE+ +M+++ Sbjct: 5 IGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENL-KKIFREVQIMKMLC 63 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++++L++VM T+ IY V EYA GGE+F+ +V G++ E ARR F Q+++A+ +CH Sbjct: 64 HPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHC 123 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 R + HR ++DFG S L + LL T CG+P Y APE+ K Sbjct: 124 RNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ---LLKTWCGSPPYAAPELFEGKE 180 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG K D+WS GV+L+VLV G LPF + L + R+ F+ P + S E + L+ +L Sbjct: 181 YDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHML 240 Query: 1208 DPDPSTRIPISRIKKSAWYR 1267 DP+ R+ + +I K W + Sbjct: 241 VLDPNKRLSMEQICKHKWMK 260
>Q6P4S6:QSK_MOUSE Serine/threonine-protein kinase QSK - Mus musculus (Mouse)| Length = 1311 Score = 195 bits (495), Expect = 7e-49 Identities = 99/260 (38%), Positives = 156/260 (60%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G YEI + +G+G FA V A +L T VAIK+I+K ++ + L ++I RE+ +M+++ Sbjct: 5 IGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQLDEENL-KKIFREVQIMKMLC 63 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++++L++VM T+ IY V EYA GGE+F+ +V G++ E ARR F Q+++A+ +CH Sbjct: 64 HPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHC 123 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 R + HR ++DFG S L + LL T CG+P Y APE+ K Sbjct: 124 RNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ---LLKTWCGSPPYAAPELFEGKE 180 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG K D+WS GV+L+VLV G LPF + L + R+ F+ P + S E + L+ +L Sbjct: 181 YDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHML 240 Query: 1208 DPDPSTRIPISRIKKSAWYR 1267 DP+ R+ + +I + W + Sbjct: 241 VLDPNKRLSMEQICRHKWMK 260
>Q6NSM8:QSK_DANRE Serine/threonine-protein kinase QSK homolog - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 1187 Score = 194 bits (493), Expect = 1e-48 Identities = 97/261 (37%), Positives = 158/261 (60%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G YE+ + +G+G FA V A ++ T VAIK+++K ++ L ++I RE+ +M++++ Sbjct: 56 VGYYEMERTIGKGNFAVVKLATHMITKAKVAIKIVDKTQLDDENL-KKIFREVQIMKMLR 114 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++++L++VM T+ IY V EYA GGE+F+ +V G++ E ARR F Q+++A+ +CH Sbjct: 115 HPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKDARRKFKQIVAAVYFCHC 174 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 R + HR ++DFG S L + LL T CG+P Y APE+ K Sbjct: 175 RSIVHRDLKAENLLLDHNLNIKIADFGFSNLFSRGQ---LLKTWCGSPPYAAPELFEGKE 231 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG K D+WS GV+L+VLV G LPF + L + R+ F+ P + S + + L+ +L Sbjct: 232 YDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTDCEYLIRHML 291 Query: 1208 DPDPSTRIPISRIKKSAWYRR 1270 +PS R+ + +I K+ W R+ Sbjct: 292 ILEPSRRLSMEQICKNKWMRQ 312
>Q60670:SN1L1_MOUSE Serine/threonine-protein kinase SNF1-like kinase 1 - Mus musculus| (Mouse) Length = 779 Score = 194 bits (492), Expect = 2e-48 Identities = 98/264 (37%), Positives = 161/264 (60%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 +++ + +G Y++ + LG+G FA V AR+ T VAIK+I+K ++ L E+I RE+ Sbjct: 18 QQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNL-EKIYREVQ 76 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 +M+L+ HPN+++L++VM TK +Y V E+AK GE+F+ + G L+E+ AR+ F Q++SA Sbjct: 77 LMKLLNHPNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSA 136 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 ++YCH+ + HR ++DFG + + L T G+P Y APE Sbjct: 137 VEYCHNHHIVHRDLKTENLLLDSNMDIKLADFG---FGNFYKPGEPLSTCVGSPPYAAPE 193 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 V K Y+G + DVWS GV+L+VLV G LPF NL + +R+ + F+ P + S + + Sbjct: 194 VFEGKEYEGPQLDVWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCET 253 Query: 1190 LLHKILDPDPSTRIPISRIKKSAW 1261 L+ ++L DP+ RI I++I++ W Sbjct: 254 LIRRMLVVDPAKRITIAQIRQHRW 277
>P27448:MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 - Homo sapiens (Human)| Length = 776 Score = 192 bits (488), Expect = 5e-48 Identities = 111/325 (34%), Positives = 170/325 (52%), Gaps = 24/325 (7%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y + K +G+G FAKV AR++ TG+ VAIK+I+K ++ L +++ RE+ +M+++ Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSL-QKLFREVRIMKILN 111 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQ---------- 817 HPN+++LFEV+ T+ +Y ++EYA GGE+F+ +V G++ E AR F Q Sbjct: 112 HPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKV 171 Query: 818 -------------LISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQ 958 ++SA+ YCH + + HR ++DFG S Sbjct: 172 QVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVG-- 229 Query: 959 DGLLHTTCGTPAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRI 1138 G L T CG+P Y APE+ K YDG + DVWS GVIL+ LV+G LPF NL E+ R+ Sbjct: 230 -GKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 288 Query: 1139 SKADFKCPRYFSAELKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHT 1318 + ++ P Y S + ++LL + L +P R + +I K W E + K E Sbjct: 289 LRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELD 348 Query: 1319 FSAEAASSVSTGCSTS-ERNQGSLS 1390 S + + G S E Q SLS Sbjct: 349 ISDQKRIDIMVGMGYSQEEIQESLS 373
>Q02723:RKIN1_SECCE Carbon catabolite derepressing protein kinase - Secale cereale (Rye)| Length = 502 Score = 191 bits (486), Expect = 8e-48 Identities = 102/261 (39%), Positives = 159/261 (60%), Gaps = 4/261 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL---VK 667 Y +GK LG GTFAKV A + T VAIK++N+ ++ + E+ KREI ++RL + Sbjct: 14 YYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRLFIDLI 73 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++++++EV+ T I+ V+EY + G+L + I+++ +L ED ARR F Q+ISA++YCH Sbjct: 74 HPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVEYCHR 133 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLSRK 1024 V HR ++DFGLS + DG L T+CG+ Y APEV+S K Sbjct: 134 NKVVHRDLKPENLLLDSKYNVKLADFGLSNVM----HDGHFLKTSCGSLNYAAPEVISGK 189 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + DVWS GVIL+ L+ G +PF + N+ ++++I + P Y S ++DL+ ++ Sbjct: 190 LYAGPEIDVWSCGVILYALLCGAVPFDDDNIPNLFKKIKGGTYILPIYLSDLVRDLISRM 249 Query: 1205 LDPDPSTRIPISRIKKSAWYR 1267 L DP RI I I+K +W++ Sbjct: 250 LIVDPMKRITIGEIRKHSWFQ 270
>O74536:SNF1_SCHPO SNF1-like protein kinase ssp2 - Schizosaccharomyces pombe (Fission| yeast) Length = 576 Score = 191 bits (485), Expect = 1e-47 Identities = 98/272 (36%), Positives = 164/272 (60%), Gaps = 8/272 (2%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y I + LG+G+F KV A + T Q VA+K I++ + K + +++REIS ++L++ Sbjct: 31 IGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLR 90 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++++L++V+ T + I V+EYA GGELF+ IV++ ++ ED RR+F Q+I AI+YCH Sbjct: 91 HPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHR 149 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-LLHTTCGTPAYVAPEVLSRK 1024 + HR ++DFGLS + DG L T+CG+P Y APEV++ K Sbjct: 150 HKIVHRDLKPENLLLDDNLNVKIADFGLSNIMT----DGNFLKTSCGSPNYAAPEVINGK 205 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + DVWS G++L+V++ G LPF + + ++++++ + P + S + L+ ++ Sbjct: 206 LYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRM 265 Query: 1205 LDPDPSTRIPISRIKKSAW-------YRRPVE 1279 + DP RI I I++ W Y RP+E Sbjct: 266 IVADPMQRITIQEIRRDPWFNVNLPDYLRPME 297
>Q61846:MELK_MOUSE Maternal embryonic leucine zipper kinase - Mus musculus (Mouse)| Length = 643 Score = 189 bits (480), Expect = 4e-47 Identities = 100/273 (36%), Positives = 163/273 (59%), Gaps = 4/273 (1%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L+ YE+ + +G G FAKV A ++ TG+ VAIK+++K+ + + ++K EI ++ + Sbjct: 7 LLKYYELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSD--LPRVKTEIDALKSL 64 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 +H ++ QL+ V+ TK+KI+ VLEY GGELF+ I+ + +L+E+ R F Q++SA+ Y H Sbjct: 65 RHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVH 124 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 S+G HR + DFGL A +D L T CG+ AY APE++ K Sbjct: 125 SQGYAHRDLKPENLLFDENHKLKLIDFGLCAKPK-GNKDYHLQTCCGSLAYAAPELIQGK 183 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G++ADVWS G++L+VL+ G+LPF + N++ +Y++I + ++ P++ S LL ++ Sbjct: 184 SYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSILLLQQM 243 Query: 1205 LDPDPSTRIPISRIKKSAW----YRRPVEVNAK 1291 L DP RI + + W Y PVE +K Sbjct: 244 LQVDPKKRISMRNLLNHPWVMQDYSCPVEWQSK 276
>Q14680:MELK_HUMAN Maternal embryonic leucine zipper kinase - Homo sapiens (Human)| Length = 651 Score = 189 bits (480), Expect = 4e-47 Identities = 102/273 (37%), Positives = 160/273 (58%), Gaps = 4/273 (1%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L+ YE+ + +G G FAKV A ++ TG+ VAIK++ DK T + +IK EI ++ + Sbjct: 7 LLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIM--DKNTLGSDLPRIKTEIEALKNL 64 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 +H ++ QL+ V+ T +KI+ VLEY GGELF+ I+ + +L+E+ R F Q++SA+ Y H Sbjct: 65 RHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVH 124 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 S+G HR + DFGL A +D L T CG+ AY APE++ K Sbjct: 125 SQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPK-GNKDYHLQTCCGSLAYAAPELIQGK 183 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G++ADVWS G++L+VL+ G+LPF + N++ +Y++I + + P++ S LL ++ Sbjct: 184 SYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQM 243 Query: 1205 LDPDPSTRIPISRIKKSAW----YRRPVEVNAK 1291 L DP RI + + W Y PVE +K Sbjct: 244 LQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSK 276
>Q12263:GIN4_YEAST Serine/threonine-protein kinase GIN4 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1142 Score = 189 bits (480), Expect = 4e-47 Identities = 109/273 (39%), Positives = 155/273 (56%), Gaps = 18/273 (6%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINK--------------DKVTKVGLI 625 +G +++G+ LG G+ KV ARN +TGQ A+K+I+K T L Sbjct: 16 IGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALP 75 Query: 626 EQIKREISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARR 805 I+REI +M+L+ HPNVL+L++V T + +Y VLEYA+ GELFN +V+ G L E A R Sbjct: 76 YGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIR 135 Query: 806 YFHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCG 985 +F Q+I + YCH+ G+ HR ++DFG++AL + LL T+CG Sbjct: 136 FFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAAL---ETEGKLLETSCG 192 Query: 986 TPAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHET--NLIEMYRRISKADFKC 1159 +P Y APE++S Y G +DVWS GVILF L+ G LPF E N+ + ++ K +F+ Sbjct: 193 SPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEM 252 Query: 1160 PR--YFSAELKDLLHKILDPDPSTRIPISRIKK 1252 P S E +DL+ KIL DP RI I K Sbjct: 253 PSDDEISREAQDLIRKILTVDPERRIKTRDILK 285
>Q9NRH2:SNRK_HUMAN SNF-related serine/threonine-protein kinase - Homo sapiens (Human)| Length = 765 Score = 182 bits (462), Expect = 5e-45 Identities = 101/261 (38%), Positives = 151/261 (57%), Gaps = 2/261 (0%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 + G Y++ K LG+G FA V AR++ TG+ VA+K+I+K K+ + + +E+ M+LV Sbjct: 12 IAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLAT-GHLFQEVRCMKLV 70 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVK-EGKLNEDAARRYFHQLISAIDYC 841 +HPN+++L+EV+ T++K+Y +LE GG++F+ I+K E LNED A++YF Q++ AI YC Sbjct: 71 QHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYC 130 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXX-VSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLS 1018 H V HR ++DFG S ++ L T+CG+ AY APE+L Sbjct: 131 HKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILL 187 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 YD D+WS GVILF+LV G PF E N E I + P + S E KDL+ Sbjct: 188 GDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLIT 247 Query: 1199 KILDPDPSTRIPISRIKKSAW 1261 ++L DP R + I+ W Sbjct: 248 RMLQRDPKRRASLEEIENHPW 268
>P34244:HSL1_YEAST Probable serine/threonine-protein kinase HSL1 - Saccharomyces| cerevisiae (Baker's yeast) Length = 1518 Score = 182 bits (461), Expect = 6e-45 Identities = 101/291 (34%), Positives = 156/291 (53%), Gaps = 36/291 (12%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKV----TKVGLIEQ-------- 631 +G +++GK LG+G+ +V A+N+ TGQ AIK++ K K + G + Sbjct: 78 VGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVT 137 Query: 632 -----------------------IKREISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAK 742 I+REI +M+L+ H NV+ LFEV KS++Y VLEY Sbjct: 138 SNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVD 197 Query: 743 GGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGVYHR-XXXXXXXXXXXXXXXXVS 919 GGELF+ +V +GKL E A YF Q++ + YCHS + HR ++ Sbjct: 198 GGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIA 257 Query: 920 DFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLP 1099 DFG++AL + LL T+CG+P Y +PE++ + Y G +DVWS G++LF L+ G+LP Sbjct: 258 DFGMAAL---ELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLP 314 Query: 1100 FHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPDPSTRIPISRIKK 1252 F++ N+ ++ ++ ++ P S+E +DL+ KIL DP RI I K Sbjct: 315 FNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILK 365
>P45894:AAPK1_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-1 -| Caenorhabditis elegans Length = 589 Score = 181 bits (460), Expect = 8e-45 Identities = 89/260 (34%), Positives = 146/260 (56%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G + I + +G+G F V ++ TG VAIK++N+ ++ +G + + + EI ++ + Sbjct: 21 IGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLT 80 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP++ +LF V++T S I+ V+E GGELF+ I ++G L +RRYF Q+IS + YCH+ Sbjct: 81 HPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHN 140 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + HR ++DFGLS + LL T CG+P Y APE++S K Sbjct: 141 HMIVHRDLKPENLLLDANKNIKIADFGLS---NYMTDGDLLSTACGSPNYAAPELISNKL 197 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 Y G + D+WS GVIL+ ++ G LPF + N+ ++ +I + P + DL+ +L Sbjct: 198 YVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTML 257 Query: 1208 DPDPSTRIPISRIKKSAWYR 1267 DP R + RI +W+R Sbjct: 258 QVDPVKRADVKRIVNHSWFR 277
>Q91819:STK6L_XENLA Serine/threonine-protein kinase Eg2-like - Xenopus laevis (African| clawed frog) Length = 408 Score = 181 bits (458), Expect = 1e-44 Identities = 95/271 (35%), Positives = 152/271 (56%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +EIG+ LG+G F VY AR + +A+K++ K ++ K G+ Q++RE+ + ++HPN Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPN 199 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +L+L+ S++Y +L+YA GGELF ++ K + ++ + Y QL A+ YCHS+ V Sbjct: 200 ILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHSKKV 259 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG S A +R+ T CGT Y+ PE++ + +D Sbjct: 260 IHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD- 314 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 K D+WS GV+ + + G PF E YRRISK +F+ P Y S E KDL+ K+L + Sbjct: 315 EKVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEAKDLVSKLLKHN 374 Query: 1217 PSTRIPISRIKKSAWYRRPVEVNAKKTEPEA 1309 P+ R+P+ + + W + + KK EP A Sbjct: 375 PNHRLPLKGVLEHPWIVKNSQQPKKKDEPLA 405
>P25389:KCC4_YEAST Probable serine/threonine-protein kinase KCC4 - Saccharomyces| cerevisiae (Baker's yeast) Length = 1037 Score = 180 bits (457), Expect = 2e-44 Identities = 105/265 (39%), Positives = 150/265 (56%), Gaps = 12/265 (4%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVG--------LIEQIKRE 643 +G +++G+ LG G+ KV A++ TG A+K+I+K G L I+RE Sbjct: 18 IGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIERE 77 Query: 644 ISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLI 823 I +M+L+ HPNVL L++V T + +Y +LEYA+ GELFN +V G L E A F Q+I Sbjct: 78 IVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQII 137 Query: 824 SAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVA 1003 I YCH+ G+ HR ++DFG++AL A LL T+CG+P Y A Sbjct: 138 IGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDA---DLLETSCGSPHYAA 194 Query: 1004 PEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHET--NLIEMYRRISKADFKCPR--YF 1171 PE++S Y+G +DVWS GVILF L+ G LPF E N+ ++ ++ K F+ P Sbjct: 195 PEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEI 254 Query: 1172 SAELKDLLHKILDPDPSTRIPISRI 1246 S + +DL+ KIL DP RI I I Sbjct: 255 SRDAQDLIGKILVVDPRQRIKIRDI 279
>Q63553:SNRK_RAT SNF-related serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 746 Score = 178 bits (452), Expect = 7e-44 Identities = 100/261 (38%), Positives = 150/261 (57%), Gaps = 2/261 (0%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 + G Y++ K LG+G FA V AR++ TG+ VA+K+I+K K+ + + +E+ M+LV Sbjct: 12 IAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLAT-GHLFQEVRCMKLV 70 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVK-EGKLNEDAARRYFHQLISAIDYC 841 +HPN+++L+EV+ T++K+Y +LE GG++F+ I+K E LNED A++YF Q++ AI YC Sbjct: 71 QHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYC 130 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXX-VSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLS 1018 H V HR ++DFG S ++ L T+CG+ AY APE+L Sbjct: 131 HKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILL 187 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 YD D+WS GVILF+LV G PF E N E I + P SA +DL+ Sbjct: 188 GDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLIT 247 Query: 1199 KILDPDPSTRIPISRIKKSAW 1261 ++L DP R + I+ W Sbjct: 248 RMLQRDPKRRASLEEIESHPW 268
>Q8VDU5:SNRK_MOUSE SNF-related serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 748 Score = 178 bits (452), Expect = 7e-44 Identities = 100/261 (38%), Positives = 150/261 (57%), Gaps = 2/261 (0%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 + G Y++ K LG+G FA V AR++ TG+ VA+K+I+K K+ + + +E+ M+LV Sbjct: 12 IAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLAT-GHLFQEVRCMKLV 70 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVK-EGKLNEDAARRYFHQLISAIDYC 841 +HPN+++L+EV+ T++K+Y +LE GG++F+ I+K E LNED A++YF Q++ AI YC Sbjct: 71 QHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYC 130 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXX-VSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLS 1018 H V HR ++DFG S ++ L T+CG+ AY APE+L Sbjct: 131 HKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILL 187 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 YD D+WS GVILF+LV G PF E N E I + P SA +DL+ Sbjct: 188 GDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLIT 247 Query: 1199 KILDPDPSTRIPISRIKKSAW 1261 ++L DP R + I+ W Sbjct: 248 RMLQRDPKRRASLEEIESHPW 268
>Q75LR7:SAPK1_ORYSJ Serine/threonine-protein kinase SAPK1 - Oryza sativa subsp. japonica| (Rice) Length = 342 Score = 176 bits (445), Expect = 5e-43 Identities = 106/279 (37%), Positives = 149/279 (53%), Gaps = 14/279 (5%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M RYE+ + +G G F R++AT A+K I + + + E ++REI R +K Sbjct: 1 MERYEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIERG----LKIDEHVQREIMNHRSLK 56 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++ EV+ T + + V+EYA GGELF +I G+ +ED AR +F QLIS + YCHS Sbjct: 57 HPNIIRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHS 116 Query: 848 RGVYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPE 1009 V HR + DFG S + +LH +T GTPAY+APE Sbjct: 117 MQVCHRDLKLENTLLDGSVTPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPE 169 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHE----TNLIEMYRRISKADFKCPRY--F 1171 VLSRK YDG ADVWS GV L+V++ G PF + N + RI + P Y Sbjct: 170 VLSRKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDDPRNFRKTITRILSVQYSIPDYVRV 229 Query: 1172 SAELKDLLHKILDPDPSTRIPISRIKKSAWYRR--PVEV 1282 SA+ + LL +I +P RI I IK W+ + P+E+ Sbjct: 230 SADCRHLLSRIFVGNPEQRITIPEIKNHPWFLKNLPIEM 268
>Q75V63:SAPK3_ORYSA Serine/threonine-protein kinase SAPK3 - Oryza sativa (Rice)| Length = 334 Score = 175 bits (444), Expect = 6e-43 Identities = 109/281 (38%), Positives = 151/281 (53%), Gaps = 14/281 (4%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 RYE K+LG G F R+ + + VA+K I + K + E ++REI R ++HP Sbjct: 4 RYEALKELGAGNFGVARLVRDKRSKELVAVKYIERGKK----IDENVQREIINHRSLRHP 59 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 N+++ EV T + + V+EYA GGELF +I G+ +ED AR +F QLIS + YCHS Sbjct: 60 NIIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLE 119 Query: 854 VYHRXXXXXXXXXXXXXXXXVS--DFGLSALADCARQDGLLH----TTCGTPAYVAPEVL 1015 + HR V DFG S + LLH +T GTPAY+APEVL Sbjct: 120 ICHRDLKLENTLLDGSPTPRVKICDFGYS-------KSALLHSKPKSTVGTPAYIAPEVL 172 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHE----TNLIEMYRRISKADFKCPRY--FSA 1177 SRK YDG ADVWS GV L+V++ G PF + N + RI + P Y S+ Sbjct: 173 SRKEYDGKVADVWSCGVTLYVMLVGSYPFEDPGDPRNFRKTISRILGVQYSIPDYVRVSS 232 Query: 1178 ELKDLLHKILDPDPSTRIPISRIKKSAWYRR--PVEVNAKK 1294 + + LL +I DPS RI I IKK W+ + P E++ ++ Sbjct: 233 DCRRLLSQIFVADPSKRITIPEIKKHTWFLKNLPKEISERE 273
>Q91820:STK6_XENLA Serine/threonine-protein kinase 6 - Xenopus laevis (African clawed| frog) Length = 407 Score = 175 bits (443), Expect = 8e-43 Identities = 92/269 (34%), Positives = 151/269 (56%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +EIG+ LG+G F VY AR + +A+K++ K ++ K G+ Q++RE+ + ++HPN Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPN 199 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +L+L+ S++Y +L+YA GGELF ++ K + ++ + Y QL A+ YCHS+ V Sbjct: 200 ILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHSKKV 259 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG S A +R+ T CGT Y+ PE++ + +D Sbjct: 260 IHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD- 314 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 D+WS GV+ + + G PF E YRRISK +F+ P Y S E +DL+ K+L + Sbjct: 315 ETVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEARDLVSKLLKHN 374 Query: 1217 PSTRIPISRIKKSAWYRRPVEVNAKKTEP 1303 P+ R+P+ + + W + ++ KK EP Sbjct: 375 PNHRLPLKGVLEHPWIIKNSQLK-KKDEP 402
>Q75H77:SAPKA_ORYSJ Serine/threonine-protein kinase SAPK10 - Oryza sativa subsp. japonica| (Rice) Length = 362 Score = 174 bits (441), Expect = 1e-42 Identities = 104/270 (38%), Positives = 147/270 (54%), Gaps = 13/270 (4%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINK-DKVTKVGLIEQIKREISVMRLVKH 670 RYE+ + +G G F R+ A GQ VA+K I + DK+ E ++REI R ++H Sbjct: 22 RYELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGDKID-----ENVQREIINHRSLRH 76 Query: 671 PNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSR 850 PN+++ EV+ T + + V+EYA GGELF +I G+ +ED AR +F QLIS + YCHS Sbjct: 77 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSM 136 Query: 851 GVYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPEV 1012 V HR + DFG S + +LH +T GTPAY+APEV Sbjct: 137 QVCHRDLKLENTLLDGSTAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEV 189 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHE----TNLIEMYRRISKADFKCPRY--FS 1174 L +K YDG ADVWS GV L+V++ G PF + N + +RI + P Y S Sbjct: 190 LLKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILGVQYSIPDYVHIS 249 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAWY 1264 E +DL+ +I +P+TRI I I+ W+ Sbjct: 250 PECRDLIARIFVANPATRISIPEIRNHPWF 279
>Q75V57:SAPK9_ORYSJ Serine/threonine-protein kinase SAPK9 - Oryza sativa subsp. japonica| (Rice) Length = 361 Score = 174 bits (440), Expect = 2e-42 Identities = 101/273 (36%), Positives = 150/273 (54%), Gaps = 12/273 (4%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 RYE+ K++G G F RN A+G VA+K I++ + + E ++REI R ++HP Sbjct: 21 RYELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGEK----IDENVQREIINHRSLRHP 76 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 N+++ EV+ T + + V+EYA GGELF +I G+ +ED AR +F QLIS + YCHS Sbjct: 77 NIIRFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQ 136 Query: 854 VYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPEVL 1015 V HR + DFG S + +LH +T GTPAY+APEVL Sbjct: 137 VCHRDLKLENTLLDGSTAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVL 189 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHE----TNLIEMYRRISKADFKCPRY--FSA 1177 +K YDG ADVWS GV L+V++ G PF + N + ++I + P Y S Sbjct: 190 LKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIQKILGVQYSIPDYVHISP 249 Query: 1178 ELKDLLHKILDPDPSTRIPISRIKKSAWYRRPV 1276 E +DL+ +I +P++RI + IK W+ + + Sbjct: 250 ECRDLITRIFVGNPASRITMPEIKNHPWFMKNI 282
>Q01919:KIN4_YEAST Serine/threonine-protein kinase KIN4 - Saccharomyces cerevisiae| (Baker's yeast) Length = 800 Score = 174 bits (440), Expect = 2e-42 Identities = 102/281 (36%), Positives = 156/281 (55%), Gaps = 14/281 (4%) Frame = +2 Query: 467 DERRTILMGRYEIGKQLGQGTFAKVYYARNLATG-----QAVAIKMINKDKVTKVGLIE- 628 ++R+ G Y IG LG+G F KV A+ + VAIK+I +D + K E Sbjct: 36 NQRKHATFGPYIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEI 95 Query: 629 QIKREISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRY 808 +I REI+ ++ + HPN++ L EV+ I VLE+ GGE + I ++ +L E +A R Sbjct: 96 KIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRL 155 Query: 809 FHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGT 988 F QLIS ++Y H +G+ HR ++DFG + + + L+ T+CG+ Sbjct: 156 FAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGF--VNEFFEDNELMKTSCGS 213 Query: 989 PAYVAPE-VLSRKGYDGAKADVWSSGVILFVLVAGYLPF---HET----NLIEMYRRISK 1144 P Y APE V+S K Y+ KADVWS GVIL+ ++AGYLP+ HE ++ +Y+ I++ Sbjct: 214 PCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQ 273 Query: 1145 ADFKCPRYFSAELKDLLHKILDPDPSTRIPISRIKKSAWYR 1267 K P Y + +DLL +IL P+P RI + IK+ W + Sbjct: 274 TPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWLK 314
>O60285:NUAK1_HUMAN NUAK family SNF1-like kinase 1 - Homo sapiens (Human)| Length = 661 Score = 172 bits (437), Expect = 4e-42 Identities = 91/259 (35%), Positives = 145/259 (55%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L RYE+ + LG+GT+ KV A +G+ VAIK I KDK+ + I+REI +M + Sbjct: 51 LKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSL 110 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP+++ ++EV K KI ++EYA GEL++ I + +L+E R +F Q++SA+ YCH Sbjct: 111 NHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 170 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 GV HR ++DFGLS L ++D L T CG+P Y +PE+++ + Sbjct: 171 KNGVVHRDLKLENILLDDNCNIKIADFGLSNL---YQKDKFLQTFCGSPLYASPEIVNGR 227 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + D W+ GV+L+ LV G +PF + + R+IS +++ P ++ + L+ + Sbjct: 228 PYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWM 286 Query: 1205 LDPDPSTRIPISRIKKSAW 1261 L +P R I I W Sbjct: 287 LMVNPDRRATIEDIANHWW 305
>Q84TC6:SAPK2_ORYSA Serine/threonine-protein kinase SAPK2 - Oryza sativa (Rice)| Length = 339 Score = 172 bits (435), Expect = 7e-42 Identities = 104/279 (37%), Positives = 148/279 (53%), Gaps = 14/279 (5%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M RYE+ K +G G F R++ T + A+K I + + + E ++REI R ++ Sbjct: 1 MERYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQK----IDENVQREIMNHRSLR 56 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++ EV+ T + + V+EYA GGELF +I G+ +ED AR +F QLIS + YCHS Sbjct: 57 HPNIVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHS 116 Query: 848 RGVYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPE 1009 + HR + DFG S + LLH +T GTPAY+APE Sbjct: 117 MQICHRDLKLENTLLDGSIAPRLKICDFGYS-------KSSLLHSQPKSTVGTPAYIAPE 169 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHE----TNLIEMYRRISKADFKCPRY--F 1171 VL+RK YDG ADVWS GV L+V++ G PF + N + RI + P Y Sbjct: 170 VLARKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYMVPDYVRV 229 Query: 1172 SAELKDLLHKILDPDPSTRIPISRIKKSAWYRR--PVEV 1282 S E + LL +I +P RI I IK W+ + P+E+ Sbjct: 230 SMECRHLLSRIFVANPEQRITIPEIKNHPWFLKNLPIEM 268
>O13945:PPK9_SCHPO Protein kinase domain-containing protein ppk9 - Schizosaccharomyces| pombe (Fission yeast) Length = 532 Score = 171 bits (434), Expect = 9e-42 Identities = 87/284 (30%), Positives = 154/284 (54%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G + +G+ LGQG AKV ++ T + VA+KM+ D++ ++++RE++++R + Sbjct: 20 VGPWLLGRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKRLQREVTILRQLH 79 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN++ L++V LEY +L + +VK +L+E R+ F Q++ AIDYCH Sbjct: 80 HPNIITLYQVFRVPKYTVLALEYMDT-DLHSMVVKHNRLDECTTRKIFRQIVHAIDYCHL 138 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 V HR ++DFGLS + L T+CGTP Y APEV+ + Sbjct: 139 HRVAHRDLKLENILLNKDLVVKLTDFGLS---NFMLDGSFLSTSCGTPHYAAPEVIQGRY 195 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG DVW G++L++++ G PF + + + R+ K + P + S+ DL+ ++L Sbjct: 196 YDGCDVDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCKGIYTIPSFVSSSASDLIRQML 255 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAAS 1339 P++RI ++ I + W+ + +++ P T +FS++ S Sbjct: 256 MVLPTSRIKVAEIMQHPWFIADLPTHSRL--PSRTSSFSSKHRS 297
>Q641K5:NUAK1_MOUSE NUAK family SNF1-like kinase 1 - Mus musculus (Mouse)| Length = 658 Score = 171 bits (434), Expect = 9e-42 Identities = 90/259 (34%), Positives = 145/259 (55%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L RYE+ + LG+GT+ KV A +G+ VAIK I KDK+ + I+REI +M + Sbjct: 52 LKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSL 111 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP+++ ++EV K KI ++EYA GEL++ I + +L+E R +F Q++SA+ YCH Sbjct: 112 NHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 171 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 GV HR ++DFGLS L ++D L T CG+P Y +PE+++ + Sbjct: 172 KNGVVHRDLKLENILLDDNCNIKIADFGLSNL---YQKDKFLQTFCGSPLYASPEIVNGR 228 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + D W+ GV+L+ L+ G +PF + + R+IS +++ P ++ + L+ + Sbjct: 229 PYRGPEVDSWALGVLLYTLIYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWM 287 Query: 1205 LDPDPSTRIPISRIKKSAW 1261 L +P R I I W Sbjct: 288 LMVNPDRRATIEDIANHWW 306
>O88866:HUNK_MOUSE Hormonally up-regulated neu tumor-associated kinase - Mus musculus| (Mouse) Length = 714 Score = 171 bits (432), Expect = 1e-41 Identities = 97/263 (36%), Positives = 150/263 (57%), Gaps = 5/263 (1%) Frame = +2 Query: 488 MGRYEIG-KQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLI-EQIKREISVMRL 661 +G Y IG ++LG+G+FAKV ++ TG+ VAIK+I+K + K + + ++RE + ++ Sbjct: 58 VGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQM 117 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 ++HPN+ QL +++ T++ Y V+E GG L +KI ++ +L+E ARRY QLISA+++ Sbjct: 118 IRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHL 177 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 H GV HR + DFGLS A T CG+PAY APE+L+R Sbjct: 178 HRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLAR 237 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPF--HETNLIEMYRR-ISKADFKCPRYFSAELKDL 1192 K Y G K DVWS GV ++ ++ G LPF +L +Y++ + KA P S + Sbjct: 238 KKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNF 296 Query: 1193 LHKILDPDPSTRIPISRIKKSAW 1261 L +L+PDP R I + + W Sbjct: 297 LRSLLEPDPVKRPNIQQALANRW 319
>P43292:ASK2_ARATH Serine/threonine-protein kinase ASK2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 353 Score = 171 bits (432), Expect = 1e-41 Identities = 103/271 (38%), Positives = 145/271 (53%), Gaps = 12/271 (4%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M +Y++ K LG G F R+ T + VA+K I + + + E + REI R +K Sbjct: 1 MDKYDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRK----IDENVAREIINHRSLK 56 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++ EV+ T + + V+EYA GGELF++I G+ +E AR +F QLI +DYCHS Sbjct: 57 HPNIIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHS 116 Query: 848 RGVYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPE 1009 + HR + DFG S + +LH +T GTPAY+APE Sbjct: 117 LQICHRDLKLENTLLDGSPAPLLKICDFGYS-------KSSILHSRPKSTVGTPAYIAPE 169 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYR----RISKADFKCPRY--F 1171 VLSR+ YDG ADVWS GV L+V++ G PF + N + +R RI +K P Y Sbjct: 170 VLSRREYDGKHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHI 229 Query: 1172 SAELKDLLHKILDPDPSTRIPISRIKKSAWY 1264 S E K LL +I + + RI + IK WY Sbjct: 230 SQECKHLLSRIFVTNSAKRITLKEIKNHPWY 260
>O55099:AURKB_RAT Serine/threonine-protein kinase 12 - Rattus norvegicus (Rat)| Length = 343 Score = 170 bits (430), Expect = 3e-41 Identities = 91/271 (33%), Positives = 140/271 (51%) Frame = +2 Query: 455 LDRMDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQI 634 L R+ + +EIG+ LG+G F VY AR + VA+K++ K ++ K G+ Q+ Sbjct: 66 LQGSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQL 125 Query: 635 KREISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFH 814 +REI + +KHPN+LQL+ + +IY +LEYA GEL+ ++ K G +E Sbjct: 126 RREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIME 185 Query: 815 QLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPA 994 +L A+ YCH + V HR ++DFG S A R+ T CGT Sbjct: 186 ELSDALMYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRR----KTMCGTLD 241 Query: 995 YVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFS 1174 Y+ PE++ + ++ D+W GV+ + L+ G PF + E YRRI K D K P Sbjct: 242 YLPPEMIEGRMHN-EMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMP 300 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAWYR 1267 KDL+ K+L +PS R+P+ ++ W R Sbjct: 301 LGAKDLISKLLKHNPSQRLPLEQVSAHPWVR 331
>O00444:PLK4_HUMAN Serine/threonine-protein kinase PLK4 - Homo sapiens (Human)| Length = 970 Score = 169 bits (428), Expect = 4e-41 Identities = 92/299 (30%), Positives = 159/299 (53%), Gaps = 2/299 (0%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +++G LG+G+FA VY A ++ TG VAIKMI+K + K G++++++ E+ + +KHP+ Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKE--GKLNEDAARRYFHQLISAIDYCHSR 850 +L+L+ + +Y VLE GE+ N+ +K +E+ AR + HQ+I+ + Y HS Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEM-NRYLKNRVKPFSENEARHFMHQIITGMLYLHSH 130 Query: 851 GVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGY 1030 G+ HR ++DFGL+ + +T CGTP Y++PE+ +R + Sbjct: 131 GILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKH--YTLCGTPNYISPEIATRSAH 188 Query: 1031 DGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILD 1210 G ++DVWS G + + L+ G PF + ++ AD++ P + S E KDL+H++L Sbjct: 189 -GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLR 247 Query: 1211 PDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGCSTSERNQGSL 1387 +P+ R+ +S + + R +K S A S + S+S GSL Sbjct: 248 RNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSL 306
>Q6CWQ4:IPL1_KLULA Spindle assembly checkpoint kinase - Kluyveromyces lactis (Yeast)| (Candida sphaerica) Length = 361 Score = 169 bits (428), Expect = 4e-41 Identities = 90/269 (33%), Positives = 145/269 (53%), Gaps = 1/269 (0%) Frame = +2 Query: 458 DRMDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIK 637 D D+ + + +EIGK LG+G F KVY ++ TG A+K + K ++ + + +Q + Sbjct: 87 DHNDKFENMTLQDFEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYTIQKQFR 146 Query: 638 REISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQ 817 RE+ + KH N+ QL+ + ++Y ++EY GEL+ + G LNE A + +Q Sbjct: 147 REVEIQGSFKHKNLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQ 206 Query: 818 LISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH-TTCGTPA 994 + +A+DY HS+ + HR ++DFG S +DG T CGT Sbjct: 207 MANALDYMHSKNILHRDIKPENILIGFNNTIKLTDFGWSVY----NEDGQKRKTLCGTID 262 Query: 995 YVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFS 1174 Y++PE++ + Y+ K DVW+ GV+ + L+ G PF E YRRI + D K P S Sbjct: 263 YLSPELIKSREYNN-KVDVWALGVLTYELLVGSPPFEEDTKEMTYRRILRCDLKFPLNVS 321 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAW 1261 + +DL+ ++L +PS RIP+S +K AW Sbjct: 322 PQARDLIVRLLQFEPSKRIPLSEVKSHAW 350
>O88445:AURKC_MOUSE Serine/threonine-protein kinase 13 - Mus musculus (Mouse)| Length = 282 Score = 169 bits (428), Expect = 4e-41 Identities = 91/281 (32%), Positives = 149/281 (53%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 R+ + +EIG+ LG+G F +VY AR VA+K++ K ++ K GL Q++RE+ + Sbjct: 8 RKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEI 67 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++H N+L+L+ ++IY +LEYA GGEL+ ++ + KL++ +L A+ Sbjct: 68 QAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDAL 127 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 YCH + V HR +SDFG S R+ T CGT Y+ PE+ Sbjct: 128 TYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTPSLRR----KTMCGTLDYLPPEM 183 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 +++K Y+ D+W GV+ + L+ G PF + E YRRI + DFK P A +DL Sbjct: 184 IAQKPYN-EMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDL 242 Query: 1193 LHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATH 1315 + K+L PS R+ ++++ K W R ++++ P H Sbjct: 243 ISKLLRYHPSERLSLAQVLKHPWVRE----HSRRVLPPCVH 279
>Q8BHI9:NIM1_MOUSE Serine/threonine-protein kinase NIM1 - Mus musculus (Mouse)| Length = 436 Score = 169 bits (427), Expect = 6e-41 Identities = 96/285 (33%), Positives = 157/285 (55%), Gaps = 9/285 (3%) Frame = +2 Query: 440 TPFR*LDR---MDER--RTILMGR----YEIGKQLGQGTFAKVYYARNLATGQAVAIKMI 592 TPF L + DE+ R I +G+ Y I ++G G F++V + T + VAIK++ Sbjct: 46 TPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKIL 105 Query: 593 NKDKVTKVGLIEQIKREISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVK 772 +K K+ + + REIS M + HPN+++L+EV+ T SK++ V+EYA GGELF KI Sbjct: 106 DKTKLDQKTQ-RLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKIST 164 Query: 773 EGKLNEDAARRYFHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCA 952 EGKL+E ++ F Q++SA+ + H + HR V DFG S + + Sbjct: 165 EGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTV---S 221 Query: 953 RQDGLLHTTCGTPAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYR 1132 ++ +L+T CG+P Y APE+ + Y G D+W+ GV+L+ +V G +PF + ++ + Sbjct: 222 KKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKK 281 Query: 1133 RISKADFKCPRYFSAELKDLLHKILDPDPSTRIPISRIKKSAWYR 1267 I + + P++ S L+ +L P P+ R I+ I + W R Sbjct: 282 SILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWMR 326
>Q9UQB9:AURKC_HUMAN Serine/threonine-protein kinase 13 - Homo sapiens (Human)| Length = 309 Score = 169 bits (427), Expect = 6e-41 Identities = 91/276 (32%), Positives = 146/276 (52%) Frame = +2 Query: 476 RTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVM 655 R + + +EIG+ LG+G F VY AR + VA+K++ K ++ K GL Q++REI + Sbjct: 36 RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQ 95 Query: 656 RLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAID 835 ++HPN+L+L+ ++Y +LEYA GEL+ ++ K KL+E +L A+ Sbjct: 96 AHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALT 155 Query: 836 YCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVL 1015 YCH + V HR ++DFG S R+ T CGT Y+ PE++ Sbjct: 156 YCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRR----KTMCGTLDYLPPEMI 211 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLL 1195 + YD K D+W GV+ + L+ GY PF + E YRRI K D + P +DL+ Sbjct: 212 EGRTYD-EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLI 270 Query: 1196 HKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEP 1303 ++L P R+P+++I K W V+ ++++ P Sbjct: 271 SRLLRYQPLERLPLAQILKHPW----VQAHSRRVLP 302
>Q03002:YP141_YEAST Putative serine/threonine-protein kinase YPL141C - Saccharomyces| cerevisiae (Baker's yeast) Length = 865 Score = 168 bits (426), Expect = 7e-41 Identities = 105/290 (36%), Positives = 159/290 (54%), Gaps = 21/290 (7%) Frame = +2 Query: 461 RMDERRT--ILMGRYEIGKQLGQGTFAKVY--YARNLATG--------QAVAIKMINKDK 604 R DE+R + G Y +G LG+G F KV + +N + + VAIK+I +D Sbjct: 27 RTDEQRRKHVTFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDS 86 Query: 605 VTKVGLIE-QIKREISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGK 781 ++ E +I REI+ ++ + HPN+++L EV+ I VLEYA GGE + I K+ + Sbjct: 87 ISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRR 146 Query: 782 LNEDAARRYFHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQD 961 L E A R F QLIS + Y HS+G+ HR ++DFG C+R + Sbjct: 147 LKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGF-VNEFCSRNE 205 Query: 962 GLLHTTCGTPAYVAPE-VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHE-------TNL 1117 L+ T+CG+P Y APE V+S + Y+ KAD+WS GVIL+ ++AGYLP+ + +++ Sbjct: 206 -LMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDI 264 Query: 1118 IEMYRRISKADFKCPRYFSAELKDLLHKILDPDPSTRIPISRIKKSAWYR 1267 +Y I+ K P Y +DLL ++L DP RI + +IKK W + Sbjct: 265 GRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLK 314
>Q7XQP4:SAPK7_ORYSJ Serine/threonine-protein kinase SAPK7 - Oryza sativa subsp. japonica| (Rice) Length = 359 Score = 168 bits (426), Expect = 7e-41 Identities = 101/271 (37%), Positives = 145/271 (53%), Gaps = 12/271 (4%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M RYE+ K +G G F RN T + VA+K I + + + E + REI R ++ Sbjct: 1 MERYELLKDIGAGNFGVARLMRNKETKELVAMKYIPRG----LKIDENVAREIINHRSLR 56 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++ EV+ T + + V+EYA GGELF++I G+ +ED AR +F QLI + YCH Sbjct: 57 HPNIIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHF 116 Query: 848 RGVYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPE 1009 + HR + DFG S + LLH +T GTPAY+APE Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSKPKSTVGTPAYIAPE 169 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYR----RISKADFKCPRY--F 1171 VLSR+ YDG ADVWS GV L+V++ G PF + + + +R RI +K P Y Sbjct: 170 VLSRREYDGKTADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYVHV 229 Query: 1172 SAELKDLLHKILDPDPSTRIPISRIKKSAWY 1264 S + + LL +I +P+ RI I I+ W+ Sbjct: 230 SQDCRQLLSRIFVANPAKRITIREIRNHPWF 260
>Q68UT7:HUNK_PANTR Hormonally up-regulated neu tumor-associated kinase - Pan troglodytes| (Chimpanzee) Length = 714 Score = 168 bits (426), Expect = 7e-41 Identities = 96/263 (36%), Positives = 147/263 (55%), Gaps = 5/263 (1%) Frame = +2 Query: 488 MGRYEIG-KQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLI-EQIKREISVMRL 661 +G Y IG ++LG+G+FAKV ++ TG+ VAIK+I+K + K + + ++RE + ++ Sbjct: 58 VGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQM 117 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 ++HPN+ QL +++ T++ Y V+E GG L +KI ++ +L E ARRY QLISA+++ Sbjct: 118 IRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHL 177 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 H GV HR + DFGLS A T CG+PAY APE+L+R Sbjct: 178 HRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLAR 237 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPF--HETNLIEMYRR-ISKADFKCPRYFSAELKDL 1192 K Y G K DVWS GV ++ ++ G LPF +L +Y++ + K P S Sbjct: 238 KKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISF 296 Query: 1193 LHKILDPDPSTRIPISRIKKSAW 1261 L +L+PDP R I + + W Sbjct: 297 LRSLLEPDPVKRPNIQQALANRW 319
>P57058:HUNK_HUMAN Hormonally up-regulated neu tumor-associated kinase - Homo sapiens| (Human) Length = 714 Score = 168 bits (426), Expect = 7e-41 Identities = 96/263 (36%), Positives = 147/263 (55%), Gaps = 5/263 (1%) Frame = +2 Query: 488 MGRYEIG-KQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLI-EQIKREISVMRL 661 +G Y IG ++LG+G+FAKV ++ TG+ VAIK+I+K + K + + ++RE + ++ Sbjct: 58 VGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQM 117 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 ++HPN+ QL +++ T++ Y V+E GG L +KI ++ +L E ARRY QLISA+++ Sbjct: 118 IRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHL 177 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 H GV HR + DFGLS A T CG+PAY APE+L+R Sbjct: 178 HRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLAR 237 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPF--HETNLIEMYRR-ISKADFKCPRYFSAELKDL 1192 K Y G K DVWS GV ++ ++ G LPF +L +Y++ + K P S Sbjct: 238 KKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISF 296 Query: 1193 LHKILDPDPSTRIPISRIKKSAW 1261 L +L+PDP R I + + W Sbjct: 297 LRSLLEPDPVKRPNIQQALANRW 319
>Q6GPL3:AUKBB_XENLA Serine/threonine-protein kinase 12-B - Xenopus laevis (African clawed| frog) Length = 368 Score = 168 bits (425), Expect = 1e-40 Identities = 87/277 (31%), Positives = 148/277 (53%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 +R + ++IG+ LG+G F VY AR +A+K++ K ++ K G+ Q++REI + Sbjct: 92 KRKFTIDDFDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEI 151 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++HPN+L+++ + +IY +LE+A GEL+ ++ K G+ +E + + +L A+ Sbjct: 152 QSHLRHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADAL 211 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 YCH R V HR ++DFG S A R+ T CGT Y+ PE+ Sbjct: 212 QYCHERKVIHRDIKPENLLMGYKGELKIADFGWSVHAPSLRR----RTMCGTLDYLPPEM 267 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + K +D K D+W +GV+ + + G PF + E +RRI D K P + S KDL Sbjct: 268 IEGKTHD-EKVDLWCAGVLCYEFLVGMPPFDSPSHSETHRRIVNVDLKFPPFLSEGSKDL 326 Query: 1193 LHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEP 1303 + K+L P+ R+P+ + + W V+ N+++ P Sbjct: 327 ISKLLRYHPAQRLPLKGVMEHPW----VKANSRRVLP 359
>P25323:MYLK_DICDI Myosin light chain kinase - Dictyostelium discoideum (Slime mold)| Length = 295 Score = 167 bits (423), Expect = 2e-40 Identities = 93/264 (35%), Positives = 148/264 (56%), Gaps = 7/264 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YE ++LG+G F+ VY N T Q AIK+INK ++ K + +K E+ +++ V HPN Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGK-DYEKNLKMEVDILKKVNHPN 66 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L E+ T K+Y V+E GGELF+KIV++G +E A +++SA+ Y H + Sbjct: 67 IIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNI 126 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGLS + Q ++ T CGTP+YVAPEVL+ G Sbjct: 127 VHRDLKPENLLLKSKENHLEVAIADFGLSKIIG---QTLVMQTACGTPSYVAPEVLNATG 183 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYF----SAELKDLL 1195 YD + D+WS GVI ++L+ G+ PF+ + E++ +I +A+++ P + S E KD + Sbjct: 184 YD-KEVDMWSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFI 242 Query: 1196 HKILDPDPSTRIPISRIKKSAWYR 1267 K+L D S R+ + W + Sbjct: 243 GKLLVVDVSKRLNATNALNHPWLK 266
>Q6DE08:AUKBA_XENLA Serine/threonine-protein kinase 12-A - Xenopus laevis (African clawed| frog) Length = 361 Score = 167 bits (422), Expect = 2e-40 Identities = 87/277 (31%), Positives = 147/277 (53%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 +R + ++IG+ LG+G F VY AR +A+K++ K ++ K G+ Q++REI + Sbjct: 85 KRKFTIDDFDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEI 144 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++HPN+L+++ + +IY +LE+A GEL+ ++ K G+ +E + + +L A+ Sbjct: 145 QSHLRHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADAL 204 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 YCH R V HR ++DFG S A R+ T CGT Y+ PE+ Sbjct: 205 HYCHERKVIHRDIKPENLLMGYKGELKIADFGWSVHAPSLRR----RTMCGTLDYLPPEM 260 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + K +D K D+W +GV+ + + G PF + E +RRI D K P + S KDL Sbjct: 261 IEGKTHD-EKVDLWCAGVLCYEFLVGMPPFDSPSHTETHRRIVNVDLKFPPFLSDGSKDL 319 Query: 1193 LHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEP 1303 + K+L P R+P+ + + W V+ N+++ P Sbjct: 320 ISKLLRYHPPQRLPLKGVMEHPW----VKANSRRVLP 352
>Q7Y0B9:SAPK8_ORYSJ Serine/threonine-protein kinase SAPK8 - Oryza sativa subsp. japonica| (Rice) Length = 371 Score = 166 bits (421), Expect = 3e-40 Identities = 100/269 (37%), Positives = 142/269 (52%), Gaps = 12/269 (4%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 RYE+ + +G G F R+ T + VA+K I + + + + ++REI R +KHP Sbjct: 32 RYELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGEK----IDDNVQREIINHRSLKHP 87 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 N+++ EV+ T + + V+EYA GGELF +I K + +ED AR +F QLIS + YCHS Sbjct: 88 NIIRFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYCHSMQ 147 Query: 854 VYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPEVL 1015 V HR + DFG S + +LH +T GTPAY+APEVL Sbjct: 148 VCHRDLKLENTLLDGSPAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVL 200 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHE----TNLIEMYRRISKADFKCPRY--FSA 1177 +K YDG ADVWS GV L+V+V G PF + N + +RI + P S Sbjct: 201 LKKEYDGKTADVWSCGVTLYVMVVGAYPFEDPEEPKNFRKTIQRILNVQYSIPENVDISP 260 Query: 1178 ELKDLLHKILDPDPSTRIPISRIKKSAWY 1264 E + L+ +I DPS RI I I+ W+ Sbjct: 261 ECRHLISRIFVGDPSLRITIPEIRSHGWF 289
>Q6ZI44:SAPK6_ORYSJ Serine/threonine-protein kinase SAPK6 - Oryza sativa subsp. japonica| (Rice) Length = 365 Score = 166 bits (421), Expect = 3e-40 Identities = 99/273 (36%), Positives = 146/273 (53%), Gaps = 12/273 (4%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M +YE+ K +G G F RN T + VA+K I + + + E + REI R ++ Sbjct: 1 MEKYELLKDIGSGNFGVARLMRNRETKELVAMKYIPRG----LKIDENVAREIINHRSLR 56 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++ EV+ T + + V+EYA GGELF++I G+ +ED +R +F QLI + YCH Sbjct: 57 HPNIIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHF 116 Query: 848 RGVYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPE 1009 + HR + DFG S + LLH +T GTPAY+APE Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSKPKSTVGTPAYIAPE 169 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYR----RISKADFKCPRY--F 1171 VLSR+ YDG ADVWS GV L+V++ G PF + + + +R RI +K P Y Sbjct: 170 VLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIVSIQYKIPEYVHI 229 Query: 1172 SAELKDLLHKILDPDPSTRIPISRIKKSAWYRR 1270 S + + LL +I +P+ RI I I+ W+ + Sbjct: 230 SQDCRQLLSRIFVANPAKRITIREIRNHPWFMK 262
>P87050:CDR2_SCHPO Mitosis inducer protein kinase cdr2 - Schizosaccharomyces pombe| (Fission yeast) Length = 775 Score = 166 bits (420), Expect = 4e-40 Identities = 79/255 (30%), Positives = 145/255 (56%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G +E+G LG G A++ TGQ +K I +I+ E+ ++RL++ Sbjct: 7 VGPWELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIE 66 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPNVLQL +V++ + +++ V+EY GGELF+ ++++G E ++ Q++ ++YCH Sbjct: 67 HPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHK 126 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 + HR + +FG++++ + LL T+CG+P Y +PE++ + Sbjct: 127 LHICHRDLKPENLYLDAHGSIKIGEFGMASIQQPGK---LLQTSCGSPHYASPEIIMGRS 183 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKIL 1207 YDG +D+WS G+I F L+ G LPF + N+ + ++ + F+ P S + + LL+++L Sbjct: 184 YDGCASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPSNISPQAQHLLYRML 243 Query: 1208 DPDPSTRIPISRIKK 1252 D D STRI + +I++ Sbjct: 244 DVDSSTRITMEQIRE 258
>Q7YRC6:AURKB_BOVIN Serine/threonine-protein kinase 12 - Bos taurus (Bovine)| Length = 344 Score = 166 bits (419), Expect = 5e-40 Identities = 86/265 (32%), Positives = 142/265 (53%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 +R+ + +EIG+ LG+G F VY AR + VA+K++ K ++ K G+ Q++REI + Sbjct: 69 KRSFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEI 128 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++HPN+L+L+ + +IY +LEYA GEL+ ++ K +E +L A+ Sbjct: 129 QAHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELADAL 188 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 YCH++ V HR ++DFG S A R+ T CGT Y+ PE+ Sbjct: 189 TYCHAKKVIHRDIKPENLLLGLRGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEM 244 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + + ++ K D+W GV+ + L+ G PF + E YRRI K D K P +D Sbjct: 245 IEGRTHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPPSVPLGAQDF 303 Query: 1193 LHKILDPDPSTRIPISRIKKSAWYR 1267 ++K+L +PS R+P++++ W R Sbjct: 304 IYKLLKHNPSERLPLAQVSAHPWVR 328
>Q64702:PLK4_MOUSE Serine/threonine-protein kinase PLK4 - Mus musculus (Mouse)| Length = 925 Score = 165 bits (418), Expect = 6e-40 Identities = 90/299 (30%), Positives = 158/299 (52%), Gaps = 2/299 (0%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +++G LG+G+FA VY A ++ TG VAIKMI+K + K G++++++ E+ + +KHP+ Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKE--GKLNEDAARRYFHQLISAIDYCHSR 850 VL+L+ + +Y VLE GE+ N+ +K +E AR + HQ+I+ + Y HS Sbjct: 72 VLELYNYFEDNNYVYLVLEMCHNGEM-NRYLKNRMKPFSEREARHFMHQIITGMLYLHSH 130 Query: 851 GVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGY 1030 G+ HR ++DFGL+ + + +T CGTP Y++PE+ +R + Sbjct: 131 GILHRDLTLSNILLTRNMNIKIADFGLATQLNMPHEKH--YTLCGTPNYISPEIATRSAH 188 Query: 1031 DGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILD 1210 G ++D+WS G + + L+ G PF + ++ AD++ P + S E +DL+H++L Sbjct: 189 -GLESDIWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPAFLSREAQDLIHQLLR 247 Query: 1211 PDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGCSTSERNQGSL 1387 +P+ R+ +S + + R +K S A S + S+ GSL Sbjct: 248 RNPADRLSLSSVLDHPFMSRNPSPKSKDVGTVEDSMDSGHATLSTTITASSGTSLSGSL 306
>P22987:KIN1_SCHPO Protein kinase kin1 - Schizosaccharomyces pombe (Fission yeast)| Length = 891 Score = 165 bits (418), Expect = 6e-40 Identities = 97/297 (32%), Positives = 149/297 (50%), Gaps = 18/297 (6%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINK-------------DKVT 610 ERR ++ G Y +GK +G G+ KV A +L TG+ AIK++ + + T Sbjct: 117 ERRKVI-GNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEAT 175 Query: 611 KVGLIEQIK-----REISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKE 775 K E+ K RE ++ L++HP + + +V T S Y V E+ GG++ + I+ Sbjct: 176 KAAQSEKNKEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISH 235 Query: 776 GKLNEDAARRYFHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCAR 955 GKL E AR++ Q+ SA+ Y H V HR + DFGLS L R Sbjct: 236 GKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLY---R 292 Query: 956 QDGLLHTTCGTPAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRR 1135 + L T CG+ + APE+L+ + Y G + DVWS G++L+VLV G +PF + N+ ++ + Sbjct: 293 RQSRLRTFCGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAK 352 Query: 1136 ISKADFKCPRYFSAELKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPE 1306 I K + P Y S++ K LL ++L DP R + + W R E PE Sbjct: 353 IKKGTVEYPSYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWMIRNYEGPPASFAPE 409
>Q9N0X0:AURKB_PIG Serine/threonine-protein kinase 12 - Sus scrofa (Pig)| Length = 344 Score = 165 bits (418), Expect = 6e-40 Identities = 88/264 (33%), Positives = 141/264 (53%) Frame = +2 Query: 476 RTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVM 655 R+ + +EIG+ LG+G F VY AR + VA+K++ K ++ K G+ Q++REI + Sbjct: 70 RSFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQ 129 Query: 656 RLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAID 835 ++HPN+L+L+ + +IY +LEYA GEL+ ++ K +E +L A+ Sbjct: 130 AHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKCRTFDEQRTATIMEELADALI 189 Query: 836 YCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVL 1015 YCH + V HR ++DFG S A R+ T CGT Y+ PE++ Sbjct: 190 YCHGKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMI 245 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLL 1195 + ++ K D+W GV+ + L+ G PF + E YRRI K D K P A +DL+ Sbjct: 246 EGRTHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIGKVDLKFPPSVPAGAQDLI 304 Query: 1196 HKILDPDPSTRIPISRIKKSAWYR 1267 K+L +PS R+P++++ W R Sbjct: 305 SKLLKHNPSDRLPLAQVSAHPWVR 328
>Q7XKA8:SAPK5_ORYSJ Serine/threonine-protein kinase SAPK5 - Oryza sativa subsp. japonica| (Rice) Length = 370 Score = 165 bits (417), Expect = 8e-40 Identities = 105/307 (34%), Positives = 154/307 (50%), Gaps = 14/307 (4%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M +YE +++G G F RN T + VA+K I + + E + REI R ++ Sbjct: 1 MEKYEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGN----RIDENVFREIVNHRSLR 56 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++ EV+ T + V+EYA GGELF +I + G+ +ED AR +F QL+ + YCH+ Sbjct: 57 HPNIIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHA 116 Query: 848 RGVYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPE 1009 + HR + DFG S + LLH +T GTPAY+APE Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSRPKSTVGTPAYIAPE 169 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHE----TNLIEMYRRISKADFKCPRY--F 1171 VLSR+ YDG ADVWS GV L+V++ G PF + N + RI +K P Y Sbjct: 170 VLSRREYDGKLADVWSCGVTLYVMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYVHV 229 Query: 1172 SAELKDLLHKILDPDPSTRIPISRIKKSAWYRR--PVEVNAKKTEPEATHTFSAEAASSV 1345 S + LL +I +P RI + IK W+ + P E+ + + AASS Sbjct: 230 SQPCRHLLSRIFVANPYKRISMGEIKSHPWFLKNLPRELKEEAQAVYYNRRGADHAASSA 289 Query: 1346 STGCSTS 1366 S+ + + Sbjct: 290 SSAAAAA 296
>Q5N942:SAPK4_ORYSJ Serine/threonine-protein kinase SAPK4 - Oryza sativa subsp. japonica| (Rice) Length = 360 Score = 165 bits (417), Expect = 8e-40 Identities = 98/271 (36%), Positives = 142/271 (52%), Gaps = 12/271 (4%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M +YE + +G G F RN T + VA+K I + + E + REI R ++ Sbjct: 1 MEKYEAVRDIGSGNFGVARLMRNRETRELVAVKCIERGH----RIDENVYREIINHRSLR 56 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++ EV+ T + + V+E+A GGELF++I G+ +ED AR +F QLI + YCH Sbjct: 57 HPNIIRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHH 116 Query: 848 RGVYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPE 1009 + HR + DFG S + +LH + GTPAY+APE Sbjct: 117 MQICHRDLKLENVLLDGSPAPRLKICDFGYS-------KSSVLHSRPKSAVGTPAYIAPE 169 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHE----TNLIEMYRRISKADFKCPRY--F 1171 VLSR+ YDG ADVWS GV L+V++ G PF + N+ + +RI +K P Y Sbjct: 170 VLSRREYDGKLADVWSCGVTLYVMLVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYVHI 229 Query: 1172 SAELKDLLHKILDPDPSTRIPISRIKKSAWY 1264 SAE K L+ +I +P RI + IK W+ Sbjct: 230 SAECKQLIARIFVNNPLRRITMKEIKSHPWF 260
>Q5R7G9:NUAK2_PONPY NUAK family SNF1-like kinase 2 - Pongo pygmaeus (Orangutan)| Length = 628 Score = 164 bits (415), Expect = 1e-39 Identities = 99/298 (33%), Positives = 157/298 (52%), Gaps = 2/298 (0%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L RYE + LG+GT+ KV AR ++G+ VAIK I KDK+ + I+REI +M + Sbjct: 49 LRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSL 107 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP+++ + EV SKI V+EYA G+L++ I + +L+E AR +F Q++SA+ YCH Sbjct: 108 NHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCH 167 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 V HR ++DFGLS L Q L T CG+P Y +PE+++ K Sbjct: 168 QNRVVHRDLKLENILLDANGNIKIADFGLSNL---YHQGKFLQTFCGSPLYASPEIVNGK 224 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + D WS GV+L++LV G +PF + + ++IS ++ P ++ L+ + Sbjct: 225 PYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPK-PSDACGLIRWL 283 Query: 1205 LDPDPSTRIPISRIKKSAW--YRRPVEVNAKKTEPEATHTFSAEAASSVSTGCSTSER 1372 L +P+ R + + W + V ++ E H S A +S++ S R Sbjct: 284 LMVNPTRRATLEDVASHWWVNWGYATRVGEQEAPHEGGHPGSDSARASMADWLRRSSR 341
>Q9H093:NUAK2_HUMAN NUAK family SNF1-like kinase 2 - Homo sapiens (Human)| Length = 628 Score = 164 bits (415), Expect = 1e-39 Identities = 99/298 (33%), Positives = 157/298 (52%), Gaps = 2/298 (0%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L RYE + LG+GT+ KV AR ++G+ VAIK I KDK+ + I+REI +M + Sbjct: 49 LRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSL 107 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP+++ + EV SKI V+EYA G+L++ I + +L+E AR +F Q++SA+ YCH Sbjct: 108 NHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCH 167 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 V HR ++DFGLS L Q L T CG+P Y +PE+++ K Sbjct: 168 QNRVVHRDLKLENILLDANGNIKIADFGLSNL---YHQGKFLQTFCGSPLYASPEIVNGK 224 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + D WS GV+L++LV G +PF + + ++IS ++ P ++ L+ + Sbjct: 225 PYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPK-PSDACGLIRWL 283 Query: 1205 LDPDPSTRIPISRIKKSAW--YRRPVEVNAKKTEPEATHTFSAEAASSVSTGCSTSER 1372 L +P+ R + + W + V ++ E H S A +S++ S R Sbjct: 284 LMVNPTRRATLEDVASHWWVNWGYATRVGEQEAPHEGGHPGSDSARASMADWLRRSSR 341
>Q6NW76:AURKB_DANRE Serine/threonine-protein kinase 12 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 320 Score = 164 bits (415), Expect = 1e-39 Identities = 81/269 (30%), Positives = 144/269 (53%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 ++IG+ LG+G F VY AR +A+K++ K ++ K G+ Q++REI + ++HPN Sbjct: 53 FDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLRHPN 112 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +L+ + ++++ +LEYA GE++ ++ + G+ ++ Y ++ A+ YCH + V Sbjct: 113 ILRFYNYFHDDTRVFLILEYAPRGEMYKELQRYGRFDDQRTATYMEEVSDALQYCHEKKV 172 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG S A R+ T CGT Y+ PE++ +D Sbjct: 173 IHRDIKPENLLLGYRGELKIADFGWSVHAPSLRR----RTMCGTLDYLPPEMIEGHSHD- 227 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 K D+WS GV+ + + G PF + E Y+RI+K D + P+ S +DL+ K+L Sbjct: 228 EKVDLWSIGVLCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHS 287 Query: 1217 PSTRIPISRIKKSAWYRRPVEVNAKKTEP 1303 PS R+P+ + + W V+ N+++ P Sbjct: 288 PSMRLPLRSVMEHPW----VKANSRRVLP 312
>P43291:ASK1_ARATH Serine/threonine-protein kinase ASK1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 363 Score = 164 bits (414), Expect = 2e-39 Identities = 103/303 (33%), Positives = 154/303 (50%), Gaps = 17/303 (5%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M +YE+ K +G G F + + + VA+K I + + E + REI R ++ Sbjct: 1 MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPK----IDENVAREIINHRSLR 56 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+++ EV+ T + + +EYA GGELF +I G+ +ED AR +F QLIS + YCH+ Sbjct: 57 HPNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHA 116 Query: 848 RGVYHR--XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPE 1009 + HR + DFG S + LLH +T GTPAY+APE Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSRPKSTVGTPAYIAPE 169 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHE----TNLIEMYRRISKADFKCPRY--F 1171 VLSR+ YDG ADVWS GV L+V++ G PF + N + ++I +K P Y Sbjct: 170 VLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHI 229 Query: 1172 SAELKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEA-----THTFSAEAA 1336 S + K+LL +I + RI I+ IKK +W+ + + +T A TFS + Sbjct: 230 SQDCKNLLSRIFVANSLKRITIAEIKKHSWFLKNLPRELTETAQAAYFKKENPTFSLQTV 289 Query: 1337 SSV 1345 + Sbjct: 290 EEI 292
>Q4KTY1:KPSH1_PINFU Serine/threonine-protein kinase H1 homolog - Pinctada fucata (Pearl| oyster) Length = 415 Score = 162 bits (411), Expect = 4e-39 Identities = 105/328 (32%), Positives = 167/328 (50%), Gaps = 18/328 (5%) Frame = +2 Query: 458 DRMDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIK 637 D+ D R T +Y+I +G+G F+KV + T Q AIKMI++ + +V + Sbjct: 70 DKFDPRVT---AKYDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDRVQGKEV-----FE 121 Query: 638 REISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQ 817 E++V+R VKH ++QL EV TK K+Y V+E A GGELF++I+ +G E A R + Sbjct: 122 SEVAVLRRVKHSYIIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNM 181 Query: 818 LISAIDYCHSRGVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGT 988 ++ + Y H G+ HR ++DFGLS+ + + TTCGT Sbjct: 182 VLDGVKYLHGLGITHRDLKPENLLYYHPGHDSKIMITDFGLSSTR--KGPENFMRTTCGT 239 Query: 989 PAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCP-- 1162 P Y+APE+++RK Y + D+W+ GVI ++L++G +PF + N +YR I KA + Sbjct: 240 PEYIAPEIIARKPY-MCQVDMWAVGVITYILLSGTMPFDDENKTRLYRLILKAKYSYAGE 298 Query: 1163 --RYFSAELKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKT----------EPE 1306 + SA+ KD + K+L P R+ + K W ++ K + Sbjct: 299 HWKDVSAQAKDFIDKLLVVSPGDRLSAADALKHQWLISNAASSSNKNLHRTISQNLIHRQ 358 Query: 1307 ATHTFSAEAASSV-STGCSTSERNQGSL 1387 +T S ++A S ST + S R+ SL Sbjct: 359 STRANSTKSAKSTRSTKSNKSNRSGRSL 386
>Q66HE5:NUAK2_RAT NUAK family SNF1-like kinase 2 - Rattus norvegicus (Rat)| Length = 630 Score = 162 bits (410), Expect = 5e-39 Identities = 91/259 (35%), Positives = 143/259 (55%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L RYE + LG+GT+ KV AR ++G+ VAIK I KDK+ + I+REI +M + Sbjct: 53 LRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSL 111 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP+++ + EV SKI V+EYA G+L++ I + +LNE AR +F Q++SA+ YCH Sbjct: 112 NHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLNERDARHFFRQIVSALHYCH 171 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 G+ HR ++DFGLS L + L T CG+P Y +PE+++ K Sbjct: 172 QNGIVHRDLKLENILLDASGNIKIADFGLSNL---YHKGKFLQTFCGSPLYASPEIVNGK 228 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + D WS GV+L++LV G +PF + + ++IS ++ P ++ L+ + Sbjct: 229 PYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISSGAYREP-CKPSDACGLIRWL 287 Query: 1205 LDPDPSTRIPISRIKKSAW 1261 L +P R + + W Sbjct: 288 LMVNPIRRATLEDVASHWW 306
>Q8IY84:NIM1_HUMAN Serine/threonine-protein kinase NIM1 - Homo sapiens (Human)| Length = 436 Score = 162 bits (410), Expect = 5e-39 Identities = 97/294 (32%), Positives = 156/294 (53%), Gaps = 14/294 (4%) Frame = +2 Query: 440 TPFR*LDR---MDER--RTILMGR----YEIGKQLGQGTFAKVYYARNLATGQAVAIKMI 592 TPF L + DE+ R I +G+ Y I ++G G F++V + T + VAIK++ Sbjct: 46 TPFEKLTQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKIL 105 Query: 593 NKDKVTKVGLIEQIKREISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVK 772 +K K+ + + REIS M + HPN+++L+EV+ T SK++ V+EYA GGELF KI Sbjct: 106 DKTKLDQKTQ-RLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKIST 164 Query: 773 EGKLNEDAARRYFHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCA 952 EGKL+E ++ F Q++SA+ + H + HR V DFG S + + Sbjct: 165 EGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTV---S 221 Query: 953 RQDGLLHTTCGTPAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYR 1132 ++ +L+T CG+P Y APE+ + Y G D+W+ GV+L+ +V G +PF + ++ + Sbjct: 222 KKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKK 281 Query: 1133 RISKADFKCPRYFSAELKDLLHKILDPDPSTRIPISRIKKSAW-----YRRPVE 1279 I + + P + S L+ +L P+ R I I W Y P+E Sbjct: 282 SILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPLE 335
>Q6C3J2:IPL1_YARLI Spindle assembly checkpoint kinase - Yarrowia lipolytica (Candida| lipolytica) Length = 371 Score = 162 bits (410), Expect = 5e-39 Identities = 92/285 (32%), Positives = 143/285 (50%), Gaps = 1/285 (0%) Frame = +2 Query: 476 RTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVM 655 R + +EIGK LG+G F KVY ++ TG A+K + K ++ + + +Q +RE+ + Sbjct: 92 RNYSLDDFEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQ 151 Query: 656 RLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAID 835 ++H NVL+LF K ++Y +LEY GEL+ + + + E A Y +Q+ A+ Sbjct: 152 SNLRHTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALL 211 Query: 836 YCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVL 1015 Y H + + HR +SDFG S A R+ T CGT Y+ PE++ Sbjct: 212 YLHGKNIIHRDIKPENILLHFNDTIKISDFGWSVHAPSNRRS----TLCGTMDYLPPEIV 267 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIE-MYRRISKADFKCPRYFSAELKDL 1192 + YD DVWS G++++ + G PF E + YRRI K D + P Y SA+ DL Sbjct: 268 QSRPYD-KNVDVWSLGILMYEFLCGAPPFEEPGGAQATYRRIVKLDLRIPPYVSADAADL 326 Query: 1193 LHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSA 1327 + ++L DP+ R + + K W R K A+H SA Sbjct: 327 IKRMLTLDPAKRFKLKDMHKHPWIVRLRPTWKYKVPKTASHERSA 371
>Q91ZN7:CHK1_RAT Serine/threonine-protein kinase Chk1 - Rattus norvegicus (Rat)| Length = 476 Score = 162 bits (410), Expect = 5e-39 Identities = 100/288 (34%), Positives = 157/288 (54%), Gaps = 4/288 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +++ + LG+G + +V A N T +AVA+K+++ + + E IK+EI + +++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRA--IDCPENIKKEICINKMLNHEN 66 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 V++ + + Y LEY GGELF++I + + E A+R+FHQL++ + Y H G+ Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGI 126 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR +SDFGL+ + ++ LL+ CGT YVAPE+L RK + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHA 186 Query: 1037 AKADVWSSGVILFVLVAGYLPFHE--TNLIEMYRRISKADFKCP--RYFSAELKDLLHKI 1204 DVWS G++L ++AG LP+ + + E K + P + SA L LLHKI Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA-LLHKI 245 Query: 1205 LDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVS 1348 L +PS RI I IKK WY +P+ AK+ P AT +E++S S Sbjct: 246 LVENPSARITIPDIKKDRWYNKPLNRGAKR--PRATSGGMSESSSGFS 291
>P07334:CDR1_SCHPO Mitosis inducer protein kinase cdr1 - Schizosaccharomyces pombe| (Fission yeast) Length = 593 Score = 162 bits (410), Expect = 5e-39 Identities = 95/262 (36%), Positives = 142/262 (54%), Gaps = 1/262 (0%) Frame = +2 Query: 464 MDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKRE 643 M +R +G + +GK LG G+ + V A++ TG AIK+I + +G+ E Sbjct: 1 MVKRHKNTIGVWRLGKTLGTGSTSCVRLAKHAKTGDLAAIKII-PIRYASIGM------E 53 Query: 644 ISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLI 823 I +MRL++HPN+L+L++V +Y LEY GELF+ I K G L+E A Y Q++ Sbjct: 54 ILMMRLLRHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQIL 113 Query: 824 SAIDYCHSRGVYHRXXXXXXXXXXXXXXXX-VSDFGLSALADCARQDGLLHTTCGTPAYV 1000 A+ +CH HR ++DFG++ + D L CG+ Y+ Sbjct: 114 DAVAHCHRFRFRHRDLKLENILIKVNEQQIKIADFGMATVEP---NDSCLENYCGSLHYL 170 Query: 1001 APEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAE 1180 APE++S K Y GA ADVWS GVIL+ L++ LPF N +Y +I + P S+ Sbjct: 171 APEIVSHKPYRGAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPSSISSA 230 Query: 1181 LKDLLHKILDPDPSTRIPISRI 1246 +DLLH++LD +PSTRI I + Sbjct: 231 AQDLLHRMLDVNPSTRITIPEV 252
>Q9BXA7:TSSK1_HUMAN Testis-specific serine/threonine-protein kinase 1 - Homo sapiens| (Human) Length = 367 Score = 162 bits (409), Expect = 7e-39 Identities = 94/271 (34%), Positives = 146/271 (53%), Gaps = 5/271 (1%) Frame = +2 Query: 464 MDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKRE 643 MD+ + Y +G LG+G++AKV A + VAIK+I++ K L + + RE Sbjct: 1 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE 60 Query: 644 ISVMRLVKHPNVLQLFEVMATK-SKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQL 820 I ++ ++ H ++++ +E+ T K+Y V+E A G+L I G L+ED AR+ FHQL Sbjct: 61 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL 120 Query: 821 ISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLS--ALADCARQDGLLHTTCGTPA 994 AI YCH V HR +SDF S L D + + L T CG+PA Sbjct: 121 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA 180 Query: 995 YVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYR--RISKADFKCPRY 1168 Y APEVL Y D+WS GVIL+++V G +P+ ++N+ +M R + + +F ++ Sbjct: 181 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH 240 Query: 1169 FSAELKDLLHKILDPDPSTRIPISRIKKSAW 1261 + E KDL++ +L PD + R+ I I W Sbjct: 241 LTGECKDLIYHMLQPDVNRRLHIDEILSHCW 271
>Q6FV07:IPL1_CANGA Spindle assembly checkpoint kinase - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 358 Score = 162 bits (409), Expect = 7e-39 Identities = 81/269 (30%), Positives = 145/269 (53%) Frame = +2 Query: 455 LDRMDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQI 634 L++ + + +E+G++LG+G F KVY R+ +G A+K I K+++ + L++Q+ Sbjct: 86 LEKSTYNNKLSLKDFEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQL 145 Query: 635 KREISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFH 814 KRE+ + + HPN+++L+ + ++Y ++E++ GEL+ + G N+ A Y + Sbjct: 146 KREVDIQLGMDHPNIIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIY 205 Query: 815 QLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPA 994 Q+ A+ Y H + + HR ++DFG S L + T CGT Sbjct: 206 QIADALHYMHKKRIIHRDVKPENVLIGFDNVVKLADFGWSILNP---EGSKRKTLCGTID 262 Query: 995 YVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFS 1174 Y++PE+++ + YD + DVW+ GV+ + LV G PF E + Y+RI K D P S Sbjct: 263 YLSPEMITPREYD-EQVDVWALGVLAYELVVGVPPFEENSKELTYKRILKCDLNFPESIS 321 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAW 1261 + KDL+ K+L D + R+ ++ +K W Sbjct: 322 KDAKDLISKLLVTDTTQRLSLTGVKTHPW 350
>O70126:AURKB_MOUSE Serine/threonine-protein kinase 12 - Mus musculus (Mouse)| Length = 345 Score = 162 bits (409), Expect = 7e-39 Identities = 86/265 (32%), Positives = 138/265 (52%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 ++ + +EIG+ LG+G F VY AR + VA+K++ K ++ K G+ Q++REI + Sbjct: 74 KQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEI 133 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 +KHPN+LQL+ + +IY +LEYA GEL+ ++ K +E +L A+ Sbjct: 134 QAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDAL 193 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 YCH + V HR ++DFG S A R+ T CGT Y+ PE+ Sbjct: 194 TYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEM 249 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + + ++ D+W GV+ + L+ G PF + E YRRI K D K P + +DL Sbjct: 250 IEGRMHN-EMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDL 308 Query: 1193 LHKILDPDPSTRIPISRIKKSAWYR 1267 + K+L +P R+P++ + W R Sbjct: 309 ISKLLKHNPWQRLPLAEVAAHPWVR 333
>Q96GD4:AURKB_HUMAN Serine/threonine-protein kinase 12 - Homo sapiens (Human)| Length = 344 Score = 162 bits (409), Expect = 7e-39 Identities = 86/257 (33%), Positives = 136/257 (52%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +EIG+ LG+G F VY AR + VA+K++ K ++ K G+ Q++REI + + HPN Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPN 136 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +L+L+ + +IY +LEYA GEL+ ++ K +E +L A+ YCH + V Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKV 196 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG S A R+ T CGT Y+ PE++ + ++ Sbjct: 197 IHRDIKPENLLLGLKGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRMHN- 251 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 K D+W GV+ + L+ G PF + E YRRI K D K P +DL+ K+L + Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 311 Query: 1217 PSTRIPISRIKKSAWYR 1267 PS R+P++++ W R Sbjct: 312 PSERLPLAQVSAHPWVR 328
>Q3SZW1:TSSK1_BOVIN Testis-specific serine/threonine-protein kinase 1 - Bos taurus| (Bovine) Length = 367 Score = 160 bits (406), Expect = 2e-38 Identities = 94/273 (34%), Positives = 145/273 (53%), Gaps = 7/273 (2%) Frame = +2 Query: 464 MDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKRE 643 MD+ + Y +G LG+G++AKV A + VA+K+I++ K L + + RE Sbjct: 1 MDDAAVLKRRGYIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPTDFLEKFLPRE 60 Query: 644 ISVMRLVKHPNVLQLFEVMATKS-KIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQL 820 I ++ ++ H ++++ +E+ T K+Y V+E G+L I G L ED AR+ FHQL Sbjct: 61 IEILAMLNHRSIIKTYEIFETSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQL 120 Query: 821 ISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG----LLHTTCGT 988 SAI YCH V HR +SDFG S C R D L T CG+ Sbjct: 121 SSAIKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKR--CLRDDSGRLTLSKTFCGS 178 Query: 989 PAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYR--RISKADFKCP 1162 AY APEVL Y D+WS GVIL+++V G +P+ ++N+ +M R + + +F Sbjct: 179 AAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRS 238 Query: 1163 RYFSAELKDLLHKILDPDPSTRIPISRIKKSAW 1261 ++ + E KDL++++L PD + R+ I I W Sbjct: 239 KHLTGECKDLIYRMLQPDVTRRLHIDEILSHCW 271
>Q755C4:IPL1_ASHGO Spindle assembly checkpoint kinase - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 367 Score = 160 bits (406), Expect = 2e-38 Identities = 79/269 (29%), Positives = 141/269 (52%) Frame = +2 Query: 464 MDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKRE 643 + + + + + +EIGK LG+G F +VY R++ +G A+K + K + + + +Q +RE Sbjct: 98 LSKLQNLKLADFEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYNIEKQFRRE 157 Query: 644 ISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLI 823 + + ++HPN+ QL+ + ++Y ++EY GEL+ + N+ A Y +Q+ Sbjct: 158 VEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMA 217 Query: 824 SAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVA 1003 A+DY H R + HR ++DFG S + + T CGT Y++ Sbjct: 218 DALDYMHERNILHRDIKPENIIIGFNNTIKLTDFGWSVITP---KGSKRKTLCGTVDYLS 274 Query: 1004 PEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAEL 1183 PE++ + Y+ K DVW+ GV+ + L+ G PF E + Y+RI K + P + E Sbjct: 275 PELIRSREYN-EKVDVWALGVLTYELLVGSPPFEEESKELTYKRILKRNLIFPDHVDTEA 333 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAWYRR 1270 + L+ ++L+ DP RIP+ +KK W + Sbjct: 334 RHLISRLLEYDPGDRIPLKEVKKHPWIEK 362
>O35280:CHK1_MOUSE Serine/threonine-protein kinase Chk1 - Mus musculus (Mouse)| Length = 476 Score = 160 bits (406), Expect = 2e-38 Identities = 100/288 (34%), Positives = 155/288 (53%), Gaps = 4/288 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +++ + LG+G + +V A N T +AVA+K+++ + + E IK+EI + +++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRA--IDCPENIKKEICINKMLSHEN 66 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 V++ + Y LEY GGELF++I + + E A+R+FHQL++ + Y H G+ Sbjct: 67 VVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGI 126 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR +SDFGL+ + ++ LL+ CGT YVAPE+L RK + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHA 186 Query: 1037 AKADVWSSGVILFVLVAGYLPFHE--TNLIEMYRRISKADFKCP--RYFSAELKDLLHKI 1204 DVWS G++L ++AG LP+ + + E K + P + SA L LLHKI Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA-LLHKI 245 Query: 1205 LDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVS 1348 L PS RI I IKK WY +P+ AK+ P AT +E++S S Sbjct: 246 LVETPSARITIPDIKKDRWYNKPLNRGAKR--PRATSGGMSESSSGFS 291
>Q61241:TSSK1_MOUSE Testis-specific serine/threonine-protein kinase 1 - Mus musculus| (Mouse) Length = 364 Score = 160 bits (405), Expect = 2e-38 Identities = 93/272 (34%), Positives = 146/272 (53%), Gaps = 6/272 (2%) Frame = +2 Query: 464 MDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKRE 643 MD+ + Y +G LG+G++AKV A + VA+K+I++ K L + + RE Sbjct: 1 MDDAAVLKRRGYIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPSDFLEKFLPRE 60 Query: 644 ISVMRLVKHPNVLQLFEVMATKS-KIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQL 820 I ++ ++ H ++++ +E+ AT K+Y V+E G+L I G L ED AR+ FHQL Sbjct: 61 IEILAMLNHRSIVKTYEIFATSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQL 120 Query: 821 ISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG----LLHTTCGT 988 SAI YCH V HR +SDFG S C R D L T CG+ Sbjct: 121 SSAIKYCHDLDVVHRDLKSENLLLDKDFNIKLSDFGFS--KRCLRDDSGRLILSKTFCGS 178 Query: 989 PAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEM-YRRISKADFKCPR 1165 AY APEVL Y D+WS GVIL+++V G +P+ ++N+ ++ ++ + +F + Sbjct: 179 AAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKLRIQKEHRVNFPRSK 238 Query: 1166 YFSAELKDLLHKILDPDPSTRIPISRIKKSAW 1261 + + E KDL++++L PD + R+ I I W Sbjct: 239 HLTGECKDLIYRMLQPDVNRRLHIDEILNHCW 270
>P59241:STK6_RAT Serine/threonine-protein kinase 6 - Rattus norvegicus (Rat)| Length = 397 Score = 160 bits (404), Expect = 3e-38 Identities = 88/293 (30%), Positives = 154/293 (52%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 ++R + ++IG+ LG+G F VY AR + +A+K++ K ++ K G+ Q++RE+ Sbjct: 117 KKRQWTLEDFDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQLRREVE 176 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 + ++HPN+L+L+ +++Y +LEYA G ++ ++ K K +E Y +L +A Sbjct: 177 IQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANA 236 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 + YCHS+ V HR ++DFG S A +R+ T CGT Y PE Sbjct: 237 LSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYQPPE 292 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 ++ + +D K D+WS GV+ + + G PF E YRRIS+ +F P + + +D Sbjct: 293 MIEGRMHD-EKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARD 351 Query: 1190 LLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVS 1348 L+ ++L + S R+ ++ + + W + A ++P H S EA S S Sbjct: 352 LISRLLKHNSSQRLTLAEVLEHPW------IKANSSKPPTGHN-SKEATSKSS 397
>O14757:CHK1_HUMAN Serine/threonine-protein kinase Chk1 - Homo sapiens (Human)| Length = 476 Score = 160 bits (404), Expect = 3e-38 Identities = 99/288 (34%), Positives = 156/288 (54%), Gaps = 4/288 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +++ + LG+G + +V A N T +AVA+K+++ + V E IK+EI + +++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRA--VDCPENIKKEICINKMLNHEN 66 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 V++ + + Y LEY GGELF++I + + E A+R+FHQL++ + Y H G+ Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGI 126 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR +SDFGL+ + ++ LL+ CGT YVAPE+L R+ + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHA 186 Query: 1037 AKADVWSSGVILFVLVAGYLPFHE--TNLIEMYRRISKADFKCP--RYFSAELKDLLHKI 1204 DVWS G++L ++AG LP+ + + E K + P + SA L LLHKI Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA-LLHKI 245 Query: 1205 LDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVS 1348 L +PS RI I IKK WY +P++ AK+ P T +E+ S S Sbjct: 246 LVENPSARITIPDIKKDRWYNKPLKKGAKR--PRVTSGGVSESPSGFS 291
>Q96PF2:TSSK2_HUMAN Testis-specific serine/threonine-protein kinase 2 - Homo sapiens| (Human) Length = 358 Score = 159 bits (403), Expect = 3e-38 Identities = 98/311 (31%), Positives = 160/311 (51%), Gaps = 8/311 (2%) Frame = +2 Query: 464 MDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQ-IKR 640 MD+ + Y +G LG+G++AKV A + VA+K+I++ K T +E+ + R Sbjct: 1 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKK-TPTDFVERFLPR 59 Query: 641 EISVMRLVKHPNVLQLFEVMATKS-KIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQ 817 E+ ++ V H ++++ +E+ T +IY ++E G+L I +G L+ED AR+ F Q Sbjct: 60 EMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQ 119 Query: 818 LISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLS--ALADCARQDGLLHTTCGTP 991 L SA+ YCH + HR +SDFG S L D + L T CG+ Sbjct: 120 LSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSA 179 Query: 992 AYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYR--RISKADFKCPR 1165 AY APEVL Y D+WS GVIL+++V G +P+ ++++ +M R + + DF + Sbjct: 180 AYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSK 239 Query: 1166 YFSAELKDLLHKILDPDPSTRIPISRIKKSAWYR--RPVEVNAKKTEPEATHTFSAEAAS 1339 + E KDL++++L PD S R+ I I +W + +P ++ + E + AE Sbjct: 240 NLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKL 299 Query: 1340 SVSTGCSTSER 1372 TG R Sbjct: 300 DTKTGLRPDHR 310
>P97477:STK6_MOUSE Serine/threonine-protein kinase 6 - Mus musculus (Mouse)| Length = 395 Score = 159 bits (403), Expect = 3e-38 Identities = 84/291 (28%), Positives = 152/291 (52%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 ++R + ++IG+ LG+G F VY AR + +A+K++ K ++ K + Q++RE+ Sbjct: 115 KKRQWTLEDFDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVE 174 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 + ++HPN+L+L+ +++Y +LEYA G ++ ++ K K +E Y +L +A Sbjct: 175 IQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANA 234 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 + YCHS+ V HR ++DFG S A +R+ T CGT Y+ PE Sbjct: 235 LSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TMCGTLDYLPPE 290 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 ++ + +D K D+WS GV+ + + G PF E YRRIS+ +F P + + +D Sbjct: 291 MIEGRMHD-EKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARD 349 Query: 1190 LLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASS 1342 L+ ++L + S R+ ++ + + W + A ++P HT + S Sbjct: 350 LISRLLKHNASQRLTLAEVLEHPW------IKANSSKPPTGHTSKEPTSKS 394
>P38991:IPL1_YEAST Spindle assembly checkpoint kinase - Saccharomyces cerevisiae| (Baker's yeast) Length = 367 Score = 159 bits (403), Expect = 3e-38 Identities = 80/270 (29%), Positives = 143/270 (52%) Frame = +2 Query: 461 RMDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKR 640 ++ + +++ + +E+GK+LG+G F KVY R+ +TG A+K++ K+++ K L +Q +R Sbjct: 92 KLPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRR 151 Query: 641 EISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQL 820 E+ + + HPN+ + + + ++Y ++EY GE++ + G N+ A Y +Q+ Sbjct: 152 EVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQI 211 Query: 821 ISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYV 1000 +A+DY H + + HR ++DFG S + + T CGT Y+ Sbjct: 212 ANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINP---PENRRKTVCGTIDYL 268 Query: 1001 APEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAE 1180 +PE++ + YD D W+ GV+ F L+ G PF E Y+RI+ D K P S + Sbjct: 269 SPEMVESREYDHT-IDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQD 327 Query: 1181 LKDLLHKILDPDPSTRIPISRIKKSAWYRR 1270 +DL+ K+L DP R+ + +K W R Sbjct: 328 AQDLILKLLKYDPKDRMRLGDVKMHPWILR 357
>Q02066:AAIP_WHEAT Abscisic acid-inducible protein kinase - Triticum aestivum (Wheat)| Length = 332 Score = 159 bits (401), Expect = 6e-38 Identities = 100/269 (37%), Positives = 138/269 (51%), Gaps = 14/269 (5%) Frame = +2 Query: 518 GQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPNVLQLFEV 697 G G F R++ T + A+K I + + E ++REI R +KHPN+++ EV Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIERGHK----IDEHVQREIMNHRSLKHPNIIRFKEV 56 Query: 698 MATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGVYHR--XX 871 + T + + V+EYA GGELF +I G+ +ED R +F QLIS + YCHS V HR Sbjct: 57 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSMQVCHRDLKL 116 Query: 872 XXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH----TTCGTPAYVAPEVLSRKGYDGA 1039 + DFG S + +LH +T GTPAY+APEVLSR+ YDG Sbjct: 117 ENTLLDGSVAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLSRREYDGK 169 Query: 1040 KADVWSSGVILFVLVAGYLPFHE----TNLIEMYRRISKADFKCPRY--FSAELKDLLHK 1201 ADVWS GV L+V++ G PF + N + RI + P Y S + LL + Sbjct: 170 VADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYSVPDYVRVSMDCIHLLSR 229 Query: 1202 ILDPDPSTRIPISRIKKSAWY--RRPVEV 1282 I +P RI I IK W+ R PVE+ Sbjct: 230 IFVGNPQQRITIPEIKNHPWFLKRLPVEM 258
>Q501V0:KPSH1_DANRE Serine/threonine-protein kinase H1 homolog - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 422 Score = 158 bits (400), Expect = 8e-38 Identities = 99/313 (31%), Positives = 162/313 (51%), Gaps = 14/313 (4%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 +Y+I +G+G+F++V + +T Q AIKMI + + G E + E+ V+R V+H Sbjct: 95 KYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMI--ETRYREGR-EVCESELCVLRRVRHT 151 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 N++QL EV T ++Y V+E A GGELF++I+ G E A R ++ + Y H+ G Sbjct: 152 NIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLG 211 Query: 854 VYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDG---LLHTTCGTPAYVAPEVL 1015 + HR ++DFGL++ R+ G L+ TTCGTP Y+APE+L Sbjct: 212 ITHRDLKPENLLYYHPGADSKIMITDFGLAS----TRKKGDECLMKTTCGTPEYIAPEIL 267 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAE----- 1180 RK Y A D+W+ GVI ++L++G +PF + N + +YR+I K + FS E Sbjct: 268 VRKPYTNA-VDMWALGVISYILLSGTMPFEDDNRMRLYRQILKGKYS----FSGEPWPSV 322 Query: 1181 ---LKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVST 1351 KD + ++L DP+ R+ + K W V + A + + S S+ Sbjct: 323 SNLAKDFIDRVLTVDPNERLSAGQALKHPWI---VSMAASSSMKNLHRSISQNLLKRASS 379 Query: 1352 GCSTSERNQGSLS 1390 C +++ +Q + S Sbjct: 380 RCHSTKSSQSTRS 392
>O14965:STK6_HUMAN Serine/threonine-protein kinase 6 - Homo sapiens (Human)| Length = 403 Score = 158 bits (399), Expect = 1e-37 Identities = 81/264 (30%), Positives = 143/264 (54%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 ++R + +EIG+ LG+G F VY AR + +A+K++ K ++ K G+ Q++RE+ Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVE 183 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 + ++HPN+L+L+ +++Y +LEYA G ++ ++ K K +E Y +L +A Sbjct: 184 IQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANA 243 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 + YCHS+ V HR ++DFG S A +R+ T CGT Y+ PE Sbjct: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPE 299 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 ++ + +D K D+WS GV+ + + G PF E Y+RIS+ +F P + + +D Sbjct: 300 MIEGRMHD-EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARD 358 Query: 1190 LLHKILDPDPSTRIPISRIKKSAW 1261 L+ ++L +PS R + + + W Sbjct: 359 LISRLLKHNPSQRPMLREVLEHPW 382
>Q9D2E1:TSSK3_MOUSE Testis-specific serine/threonine-protein kinase 3 - Mus musculus| (Mouse) Length = 268 Score = 157 bits (397), Expect = 2e-37 Identities = 89/262 (33%), Positives = 149/262 (56%), Gaps = 2/262 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 +L Y++GK +G+GT++KV A + + VAIK+I+K + + + RE+ ++R Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRT 64 Query: 662 VKHPNVLQLFEVM-ATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDY 838 + H N++Q++E++ + KIY V+E A+GG++F+ ++ G L E A+ F Q++ AI Y Sbjct: 65 LDHKNIIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRY 124 Query: 839 CHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLS 1018 CH GV HR ++DFG + + +R++ L T CG+ AY APEVL Sbjct: 125 CHGCGVAHRDLKCENALLQGFNLK-LTDFGFAKVLPKSRRE-LSQTFCGSTAYAAPEVLQ 182 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEM-YRRISKADFKCPRYFSAELKDLL 1195 +D K DVWS GV+L+V++ LPF +T++ +M +++ F S E +DLL Sbjct: 183 GIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLGISTECQDLL 242 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 ++L+PD R I + W Sbjct: 243 KRLLEPDMILRPSIEEVSWHPW 264
>O64629:AUR3_ARATH Serine/threonine-protein kinase Aurora-3 - Arabidopsis thaliana| (Mouse-ear cress) Length = 288 Score = 157 bits (397), Expect = 2e-37 Identities = 86/257 (33%), Positives = 138/257 (53%), Gaps = 2/257 (0%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +EIG+ LG+G F +VY AR + VA+K+I K+++ K + Q++RE+ + ++HPN Sbjct: 22 FEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQLRREMEIQTSLRHPN 81 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +L+LF +I+ +LEYA GGEL+ + + G L E A Y L A+ YCH + V Sbjct: 82 ILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCHGKCV 141 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG S + R+ T CGT Y+APE++ + +D Sbjct: 142 IHRDIKPENLLLDHEGRLKIADFGWSVQSSNKRK-----TMCGTLDYLAPEMVENRDHDY 196 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCP--RYFSAELKDLLHKILD 1210 A D W+ G++ + + G PF + + ++RI K D P S E K+L+ ++L Sbjct: 197 A-VDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAKNLISQLLV 255 Query: 1211 PDPSTRIPISRIKKSAW 1261 DPS R+ I +I + W Sbjct: 256 KDPSKRLSIEKIMQHPW 272
>O59790:ARK1_SCHPO Serine/threonine-protein kinase ark1 - Schizosaccharomyces pombe| (Fission yeast) Length = 355 Score = 157 bits (397), Expect = 2e-37 Identities = 82/263 (31%), Positives = 144/263 (54%), Gaps = 1/263 (0%) Frame = +2 Query: 476 RTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVM 655 R +G +EIGK LG+G F +VY A+ TG VA+K ++K ++ + + +Q++REI + Sbjct: 82 REFHIGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQ 141 Query: 656 RLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAID 835 ++H N+L+L+ + +IY +LE+A GEL+ + + + +E+ A +Y Q+ +A+ Sbjct: 142 SNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALS 201 Query: 836 YCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVL 1015 Y H + V HR +SDFG S A R+ T CGT Y+ PE++ Sbjct: 202 YLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRT----TLCGTLDYLPPEMV 257 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHE-TNLIEMYRRISKADFKCPRYFSAELKDL 1192 K + K D+WS GV+ + + G PF + + Y+RI+K D K P + + +DL Sbjct: 258 EGKEHT-EKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDL 316 Query: 1193 LHKILDPDPSTRIPISRIKKSAW 1261 + ++L +P R+ + ++ + W Sbjct: 317 ISRLLQHNPEKRMSLEQVMRHPW 339
>Q2TA06:STK6_BOVIN Serine/threonine-protein kinase 6 - Bos taurus (Bovine)| Length = 402 Score = 157 bits (396), Expect = 2e-37 Identities = 82/264 (31%), Positives = 141/264 (53%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 ++R + +EIG+ LG+G F VY AR + +A+K++ K ++ K G+ Q++RE+ Sbjct: 124 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVE 183 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 + ++HPN+L+L+ +++Y +LEYA G ++ ++ K K +E Y +L +A Sbjct: 184 IQSHLRHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANA 243 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 + YCHS+ V HR ++DFG S A +R+ T CGT Y+ PE Sbjct: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPE 299 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 ++ + +D K D+WS GV+ + + G PF E YRRIS+ +F P +D Sbjct: 300 MIEGRMHD-EKVDLWSLGVLCYEFLVGKPPFEADTYQETYRRISRVEFTFPDCVPEGARD 358 Query: 1190 LLHKILDPDPSTRIPISRIKKSAW 1261 L+ ++L +PS R + + + W Sbjct: 359 LISRLLKHNPSQRPTLKEVLEHPW 382
>Q91YA2:KPSH1_MOUSE Serine/threonine-protein kinase H1 - Mus musculus (Mouse)| Length = 424 Score = 155 bits (392), Expect = 6e-37 Identities = 98/307 (31%), Positives = 160/307 (52%), Gaps = 8/307 (2%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQI-KREISVMRLVKH 670 +Y+I +G+G+F++V + AT Q AIKMI TK ++ + E+ V+R V+H Sbjct: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIE----TKYREGREVCESELRVLRRVRH 152 Query: 671 PNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSR 850 N++QL EV T+ ++Y V+E A GGELF++I+ +G E A R ++ + Y H+ Sbjct: 153 ANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHAL 212 Query: 851 GVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 G+ HR ++DFGL A A D L+ TTCGTP Y+APEVL R Sbjct: 213 GITHRDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVR 271 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKC---PRYFSAEL-KD 1189 K Y + D+W+ GVI ++L++G +PF + N +YR+I + + P + L KD Sbjct: 272 KPYTNS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKD 330 Query: 1190 LLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGCSTSE 1369 + ++L DP R+ + + W V + A + + S S+ C +++ Sbjct: 331 FIDRLLTVDPGARMTALQALRHPWV---VSMAASSSMKNLHRSISQNLLKRASSRCQSTK 387 Query: 1370 RNQGSLS 1390 +Q + S Sbjct: 388 SSQSTRS 394
>P11801:KPSH1_HUMAN Serine/threonine-protein kinase H1 - Homo sapiens (Human)| Length = 424 Score = 155 bits (392), Expect = 6e-37 Identities = 98/311 (31%), Positives = 159/311 (51%), Gaps = 12/311 (3%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQI-KREISVMRLVKH 670 +Y+I +G+G+F++V + AT Q AIKMI TK ++ + E+ V+R V+H Sbjct: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIE----TKYREGREVCESELRVLRRVRH 152 Query: 671 PNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSR 850 N++QL EV T+ ++Y V+E A GGELF++I+ +G E A R ++ + Y H+ Sbjct: 153 ANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHAL 212 Query: 851 GVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 G+ HR ++DFGL A A D L+ TTCGTP Y+APEVL R Sbjct: 213 GITHRDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVR 271 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAE------- 1180 K Y + D+W+ GVI ++L++G +PF + N +YR+I + + +S E Sbjct: 272 KPYTNS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYS----YSGEPWPSVSN 326 Query: 1181 -LKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGC 1357 KD + ++L DP R+ + + W V + A + + S S+ C Sbjct: 327 LAKDFIDRLLTVDPGARMTALQALRHPWV---VSMAASSSMKNLHRSISQNLLKRASSRC 383 Query: 1358 STSERNQGSLS 1390 +++ Q + S Sbjct: 384 QSTKSAQSTRS 394
>Q0V7M1:KPSH1_BOVIN Serine/threonine-protein kinase H1 - Bos taurus (Bovine)| Length = 424 Score = 155 bits (392), Expect = 6e-37 Identities = 98/311 (31%), Positives = 159/311 (51%), Gaps = 12/311 (3%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQI-KREISVMRLVKH 670 +Y+I +G+G+F++V + AT Q AIKMI TK ++ + E+ V+R V+H Sbjct: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIE----TKYREGREVCESELRVLRRVRH 152 Query: 671 PNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSR 850 N++QL EV T+ ++Y V+E A GGELF++I+ +G E A R ++ + Y H+ Sbjct: 153 ANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHAL 212 Query: 851 GVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 G+ HR ++DFGL A A D L+ TTCGTP Y+APEVL R Sbjct: 213 GITHRDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVR 271 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAE------- 1180 K Y + D+W+ GVI ++L++G +PF + N +YR+I + + +S E Sbjct: 272 KPYTNS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYS----YSGEPWPSVSN 326 Query: 1181 -LKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGC 1357 KD + ++L DP R+ + + W V + A + + S S+ C Sbjct: 327 LAKDFIDRLLTVDPGARMTALQALRHPWV---VSMAASSSMKNLHRSISQNLLKRASSRC 383 Query: 1358 STSERNQGSLS 1390 +++ Q + S Sbjct: 384 QSTKSAQSTRS 394
>Q9HFF4:PPK1_SCHPO Serine/threonine-protein kinase ppk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1023 Score = 155 bits (391), Expect = 8e-37 Identities = 104/327 (31%), Positives = 161/327 (49%), Gaps = 35/327 (10%) Frame = +2 Query: 491 GRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGL-------IEQIKREIS 649 G Y +G+ +G G F KV L + I V K+ L ++ RE++ Sbjct: 490 GSYILGRTIGTGEFGKVKLGWPLPKANST-IHRSTPQVVIKIVLSTKQNCQTSRLMREVA 548 Query: 650 VMRLV--KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLI 823 +++ + HP++++ + + TK VL+Y GGELF+ I+ +L + A R F QLI Sbjct: 549 ILKGLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLI 608 Query: 824 SAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFG----------LSALADCARQDGLLH 973 S + Y HSRGV HR ++DFG LS + + L Sbjct: 609 SGVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTFGHFNTLSEHSLPTEKPDLFS 668 Query: 974 TTCGTPAYVAPEVLSRKG--YDGAKADVWSSGVILFVLVAGYLPFHE-------TNLIEM 1126 T+CG+P Y APE+++ K Y G +AD+WS GVIL+ ++AGYLPF + N+ + Sbjct: 669 TSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPFDDDPHNPNGENVPRL 728 Query: 1127 YRRISKADFKCPRYFSAELKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPE 1306 YR I P +F ++ +D+L KIL PDP+ R+ +S I A+ R V + + E Sbjct: 729 YRYICSTPLIFPEFFKSKARDILKKILVPDPAKRVRMSAIMNHAYLRSHVSLFETYNDDE 788 Query: 1307 AT-------HTFSAEAASSVSTGCSTS 1366 AT S ++ +SVS+ S S Sbjct: 789 ATSLRPSPIRLLSQKSLASVSSVSSIS 815
>Q8BZN4:NUAK2_MOUSE NUAK family SNF1-like kinase 2 - Mus musculus (Mouse)| Length = 639 Score = 154 bits (390), Expect = 1e-36 Identities = 90/267 (33%), Positives = 146/267 (54%), Gaps = 8/267 (2%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L RYE + LG+GT+ KV AR ++G+ VAIK I KDK+ + I+REI +M + Sbjct: 53 LRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSL 111 Query: 665 KHPNVLQLFEVMATK--------SKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQL 820 HP+++ + EV ++ SKI V+EYA G+L++ I + +L+E AR +F Q+ Sbjct: 112 NHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQI 171 Query: 821 ISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYV 1000 +SA+ YCH G+ HR ++DFGLS L + L T CG+P Y Sbjct: 172 VSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNL---YHKGKFLQTFCGSPLYA 228 Query: 1001 APEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAE 1180 +PE+++ K Y G + D WS GV+L++LV G +PF + + ++IS ++ P ++ Sbjct: 229 SPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISNGAYREPPK-PSD 287 Query: 1181 LKDLLHKILDPDPSTRIPISRIKKSAW 1261 L+ +L +P+ R + + W Sbjct: 288 ACGLIRWLLMVNPTRRATLEDVASHWW 314
>Q8AYC9:CHK1_CHICK Serine/threonine-protein kinase Chk1 - Gallus gallus (Chicken)| Length = 476 Score = 154 bits (388), Expect = 2e-36 Identities = 91/274 (33%), Positives = 149/274 (54%), Gaps = 8/274 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +++ + LG+G + +V A N T +AVA+K+++ + E IK+EI + +++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAADCP--ENIKKEICINKMLNHEN 66 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 V++ + + Y LEY GGELF++I + + E A+R+F QLI+ + Y HS G+ Sbjct: 67 VVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHSMGI 126 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR +SDFGL+ + ++ LL+ CGT YVAPE+L R + Sbjct: 127 THRDLKPENLLLDERDNLKISDFGLATVFKHNGRERLLNKMCGTLPYVAPELLRRPEFRA 186 Query: 1037 AKADVWSSGVILFVLVAGYLPFHE-TNLIEMYRRISKADFKCPRYFSAELKD-------L 1192 DVW+ GV+L ++AG LP+ + ++ + Y +D+K + + A + L Sbjct: 187 EPVDVWACGVVLTAMLAGELPWDQPSDSCQEY-----SDWKERKTYLAPWRKIDSAPLAL 241 Query: 1193 LHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKK 1294 LHKIL +P+ RI I IKK WY RP++ K+ Sbjct: 242 LHKILTENPTARITIPDIKKDRWYCRPLKKGTKR 275
>Q6P2M8:KCC1B_HUMAN Calcium/calmodulin-dependent protein kinase type 1B - Homo sapiens| (Human) Length = 343 Score = 153 bits (387), Expect = 2e-36 Identities = 89/262 (33%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YEI ++LG G F++V A+ + VA+K I K + G ++ EI+V+R + HPN Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALR--GKEALVENEIAVLRRISHPN 72 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L +V + S +Y +E GGELF++I++ G E A Q++ A+ Y HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR VSDFGLS + + +L T CGTP YVAPE+L +K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI----QAGNMLGTACGTPGYVAPELLEQKP 188 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYF----SAELKDLL 1195 Y G DVW+ GVI ++L+ GY PF++ + E++ +I +A ++ F S KD + Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +L+ DP R + + W Sbjct: 248 RHLLERDPQKRFTCQQALRHLW 269
>O70150:KCC1B_RAT Calcium/calmodulin-dependent protein kinase type 1B - Rattus| norvegicus (Rat) Length = 343 Score = 153 bits (386), Expect = 3e-36 Identities = 89/262 (33%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YEI ++LG G F++V A+ + VA+K I K + G ++ EI+V+R + HPN Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALR--GKEALVENEIAVLRRISHPN 72 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L +V + S +Y +E GGELF++I++ G E A Q++ A+ Y HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR VSDFGLS + + +L T CGTP YVAPE+L +K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI----QAGNMLGTACGTPGYVAPELLEQKP 188 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYF----SAELKDLL 1195 Y G DVW+ GVI ++L+ GY PF++ + E++ +I +A ++ F S KD + Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +L+ DP R + + W Sbjct: 248 RHLLERDPQKRFTCQQALQHLW 269
>Q9QYK9:KCC1B_MOUSE Calcium/calmodulin-dependent protein kinase type 1B - Mus musculus| (Mouse) Length = 343 Score = 153 bits (386), Expect = 3e-36 Identities = 89/262 (33%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YEI ++LG G F++V A+ + VA+K I K + G ++ EI+V+R + HPN Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALR--GKEALVENEIAVLRRISHPN 72 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L +V + S +Y +E GGELF++I++ G E A Q++ A+ Y HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR VSDFGLS + + +L T CGTP YVAPE+L +K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI----QAGNMLGTACGTPGYVAPELLEQKP 188 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYF----SAELKDLL 1195 Y G DVW+ GVI ++L+ GY PF++ + E++ +I +A ++ F S KD + Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +L+ DP R + + W Sbjct: 248 RHLLERDPQKRFTCQQALQHLW 269
>Q14012:KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 - Homo sapiens| (Human) Length = 370 Score = 153 bits (386), Expect = 3e-36 Identities = 89/262 (33%), Positives = 140/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y+ LG G F++V A + T + VAIK I K+ + G ++ EI+V+ +KHPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALE--GKEGSMENEIAVLHKIKHPN 77 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L ++ + +Y +++ GGELF++IV++G E A R Q++ A+ Y H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR +SDFGLS + D +L T CGTP YVAPEVL++K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKP 194 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y A D WS GVI ++L+ GY PF++ N +++ +I KA +F P + S KD + Sbjct: 195 YSKA-VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +++ DP R + + W Sbjct: 254 RHLMEKDPEKRFTCEQALQHPW 275
>P22694:KAPCB_HUMAN cAMP-dependent protein kinase, beta-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 153 bits (386), Expect = 3e-36 Identities = 87/261 (33%), Positives = 138/261 (52%), Gaps = 5/261 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E K LG G+F +V ++ AT Q A+K+++K KV K+ IE E +++ V P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R V+DFG + R G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDLL +L D Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1217 PSTRI-----PISRIKKSAWY 1264 + R +S IK W+ Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P24256:KAPB2_BOVIN cAMP-dependent protein kinase, beta-2-catalytic subunit - Bos taurus| (Bovine) Length = 397 Score = 153 bits (386), Expect = 3e-36 Identities = 87/261 (33%), Positives = 138/261 (52%), Gaps = 5/261 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E K LG G+F +V ++ AT Q A+K+++K KV K+ IE E +++ V P Sbjct: 90 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 149 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ +Y HS + Sbjct: 150 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 209 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R V+DFG + R G T CGTP Y+APE++ KGY+ Sbjct: 210 IYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNK 264 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDLL +L D Sbjct: 265 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 323 Query: 1217 PSTRI-----PISRIKKSAWY 1264 + R +S IK W+ Sbjct: 324 LTKRFGNLKNGVSDIKTHKWF 344
>P05131:KAPB1_BOVIN cAMP-dependent protein kinase, beta-1-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 153 bits (386), Expect = 3e-36 Identities = 87/261 (33%), Positives = 138/261 (52%), Gaps = 5/261 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E K LG G+F +V ++ AT Q A+K+++K KV K+ IE E +++ V P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R V+DFG + R G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDLL +L D Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1217 PSTRI-----PISRIKKSAWY 1264 + R +S IK W+ Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>Q96PN8:TSSK3_HUMAN Testis-specific serine/threonine-protein kinase 3 - Homo sapiens| (Human) Length = 268 Score = 152 bits (385), Expect = 4e-36 Identities = 87/262 (33%), Positives = 148/262 (56%), Gaps = 2/262 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 +L Y++GK +G+GT++KV A + + VAIK+I+K + + + RE+ ++R Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRT 64 Query: 662 VKHPNVLQLFEVM-ATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDY 838 + H N++Q++E++ + KI V+E A+GG++F+ ++ G L E A+ F Q++ AI Y Sbjct: 65 LDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRY 124 Query: 839 CHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLS 1018 CH GV HR ++DFG + + + ++ L T CG+ AY APEVL Sbjct: 125 CHGCGVAHRDLKCENALLQGFNLK-LTDFGFAKVLPKSHRE-LSQTFCGSTAYAAPEVLQ 182 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEM-YRRISKADFKCPRYFSAELKDLL 1195 +D K DVWS GV+L+V++ LPF +T++ +M +++ F SA+ +DLL Sbjct: 183 GIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLL 242 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 ++L+PD R I + W Sbjct: 243 KRLLEPDMILRPSIEEVSWHPW 264
>Q8IU85:KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D - Homo sapiens| (Human) Length = 385 Score = 152 bits (385), Expect = 4e-36 Identities = 89/270 (32%), Positives = 143/270 (52%), Gaps = 7/270 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E + LG G F++V A ATG+ A+K I K + G I+ EI+V+R +KH N Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK--GKESSIENEIAVLRKIKHEN 80 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L ++ + + +Y V++ GGELF++IV++G E A Q++ A+ Y H G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR +SDFGLS + + ++ T CGTP YVAPEVL++K Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSKMEG---KGDVMSTACGTPGYVAPEVLAQKP 197 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y A D WS GVI ++L+ GY PF++ N +++ +I KA +F P + S KD + Sbjct: 198 YSKA-VDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256 Query: 1196 HKILDPDPSTRIPISRIKKSAWYRRPVEVN 1285 +++ DP+ R + + W +N Sbjct: 257 RNLMEKDPNKRYTCEQAARHPWIAGDTALN 286
>P68182:KAPCB_RAT cAMP-dependent protein kinase, beta-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 152 bits (385), Expect = 4e-36 Identities = 87/261 (33%), Positives = 139/261 (53%), Gaps = 5/261 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E K LG G+F +V ++ AT Q A+K+++K KV K+ IE E +++ V+ P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R V+DFG + R G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDLL +L D Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1217 PSTRI-----PISRIKKSAWY 1264 + R +S IK W+ Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P68181:KAPCB_MOUSE cAMP-dependent protein kinase, beta-catalytic subunit - Mus musculus| (Mouse) Length = 351 Score = 152 bits (385), Expect = 4e-36 Identities = 87/261 (33%), Positives = 139/261 (53%), Gaps = 5/261 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E K LG G+F +V ++ AT Q A+K+++K KV K+ IE E +++ V+ P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R V+DFG + R G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDLL +L D Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1217 PSTRI-----PISRIKKSAWY 1264 + R +S IK W+ Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P68180:KAPCB_CRIGR cAMP-dependent protein kinase, beta-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 152 bits (385), Expect = 4e-36 Identities = 87/261 (33%), Positives = 139/261 (53%), Gaps = 5/261 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E K LG G+F +V ++ AT Q A+K+++K KV K+ IE E +++ V+ P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R V+DFG + R G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDLL +L D Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1217 PSTRI-----PISRIKKSAWY 1264 + R +S IK W+ Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P00517:KAPCA_BOVIN cAMP-dependent protein kinase, alpha-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 152 bits (385), Expect = 4e-36 Identities = 86/269 (31%), Positives = 142/269 (52%), Gaps = 5/269 (1%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + T + ++E K LG G+F +V +++ TG A+K+++K KV K+ IE E + Sbjct: 36 QNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ V P +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 155 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HS + +R V+DFG + R G T CGTP Y+APE+ Sbjct: 156 EYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEI 210 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + KGY+ A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDL Sbjct: 211 ILSKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 Query: 1193 LHKILDPDPSTRI-----PISRIKKSAWY 1264 L +L D + R ++ IK W+ Sbjct: 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWF 298
>Q8BW96:KCC1D_MOUSE Calcium/calmodulin-dependent protein kinase type 1D - Mus musculus| (Mouse) Length = 385 Score = 152 bits (384), Expect = 5e-36 Identities = 88/262 (33%), Positives = 141/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E + LG G F++V A ATG+ A+K I K + G I+ EI+V+R +KH N Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK--GKESSIENEIAVLRKIKHEN 80 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L ++ + + +Y V++ GGELF++IV++G E A Q++ A+ Y H G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR +SDFGLS + + ++ T CGTP YVAPEVL++K Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSKMEG---KGDVMSTACGTPGYVAPEVLAQKP 197 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y A D WS GVI ++L+ GY PF++ N +++ +I KA +F P + S KD + Sbjct: 198 YSKA-VDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +++ DP+ R + + W Sbjct: 257 RNLMEKDPNKRYTCEQAARHPW 278
>Q63450:KCC1A_RAT Calcium/calmodulin-dependent protein kinase type 1 - Rattus| norvegicus (Rat) Length = 374 Score = 152 bits (383), Expect = 7e-36 Identities = 89/262 (33%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y+ LG G F++V A + T + VAIK I K + G ++ EI+V+ +KHPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALE--GKEGSMENEIAVLHKIKHPN 77 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L ++ + +Y +++ GGELF++IV++G E A R Q++ A+ Y H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR +SDFGLS + D +L T CGTP YVAPEVL++K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKP 194 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y A D WS GVI ++L+ GY PF++ N +++ +I KA +F P + S KD + Sbjct: 195 YSKA-VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +++ DP R + + W Sbjct: 254 RHLMEKDPEKRFTCEQALQHPW 275
>Q91YS8:KCC1A_MOUSE Calcium/calmodulin-dependent protein kinase type 1 - Mus musculus| (Mouse) Length = 374 Score = 152 bits (383), Expect = 7e-36 Identities = 89/262 (33%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y+ LG G F++V A + T + VAIK I K + G ++ EI+V+ +KHPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALE--GKEGSMENEIAVLHKIKHPN 77 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L ++ + +Y +++ GGELF++IV++G E A R Q++ A+ Y H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR +SDFGLS + D +L T CGTP YVAPEVL++K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKP 194 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y A D WS GVI ++L+ GY PF++ N +++ +I KA +F P + S KD + Sbjct: 195 YSKA-VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +++ DP R + + W Sbjct: 254 RHLMEKDPEKRFTCEQALQHPW 275
>P05383:KAPCB_PIG cAMP-dependent protein kinase, beta-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 152 bits (383), Expect = 7e-36 Identities = 87/261 (33%), Positives = 138/261 (52%), Gaps = 5/261 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E K LG G+F +V ++ AT Q A+K+++K KV K+ IE E +++ V P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ +Y HS + Sbjct: 104 LVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R V+DFG + R G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYNK 218 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDLL +L D Sbjct: 219 A-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 1217 PSTRI-----PISRIKKSAWY 1264 + R +S IK W+ Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>O01427:AIR2_CAEEL Aurora/Ipl1-related protein kinase 2 - Caenorhabditis elegans| Length = 305 Score = 152 bits (383), Expect = 7e-36 Identities = 84/277 (30%), Positives = 139/277 (50%), Gaps = 5/277 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +EIG+ LG+G F VY AR VAIK++ K ++ G+ Q++REI + + HPN Sbjct: 30 FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPN 89 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L+ KIY VLEYA GGE++ ++ + +E A +Y +++ A+ YCH + V Sbjct: 90 IIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYMYEIADALSYCHRKNV 149 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR + DFG S A ++ T CGT Y+ PE+++ + Sbjct: 150 IHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKR----QTMCGTMDYLPPEMVNGADHSD 205 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A D+W+ GV+ + + G PF + + Y I A F P +DL+ ++L D Sbjct: 206 A-VDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDLIGRLLVVD 264 Query: 1217 PSTRIPISRIKKSAWYRRPVEVNAK-----KTEPEAT 1312 P R + ++K+ W + +E + K E EA+ Sbjct: 265 PKARCTLEQVKEHYWIQGMMEAKIRAEKQQKIEKEAS 301
>P54644:KRAC_DICDI RAC-family serine/threonine-protein kinase homolog - Dictyostelium| discoideum (Slime mold) Length = 444 Score = 151 bits (382), Expect = 9e-36 Identities = 84/264 (31%), Positives = 142/264 (53%), Gaps = 7/264 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E+ +G+G+F KV R TG+ A+K+++K + + +E E ++++ + HP Sbjct: 120 FELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKINHPF 179 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L T+ K+YF+L+Y GGELF + K+ K ED R Y +++ A+++ H GV Sbjct: 180 LVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGV 239 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTT------CGTPAYVAPEVLS 1018 +R ++DFGL ++GLL T CGTP Y+APEVL Sbjct: 240 IYRDLKPENLLLTNEGHICMTDFGLC-------KEGLLTPTDKTGTFCGTPEYLAPEVLQ 292 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLH 1198 GY G + D WS G +L+ ++ G PF+ ++ EMYR+I P + S + + LL Sbjct: 293 GNGY-GKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLE 351 Query: 1199 KILDPDPSTRI-PISRIKKSAWYR 1267 ++L+ DP R+ + IK+ ++R Sbjct: 352 QLLERDPEKRLADPNLIKRHPFFR 375
>Q9MZD9:KAPCA_SHEEP cAMP-dependent protein kinase, alpha-catalytic subunit - Ovis aries| (Sheep) Length = 351 Score = 151 bits (382), Expect = 9e-36 Identities = 86/269 (31%), Positives = 141/269 (52%), Gaps = 5/269 (1%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + T + ++E K LG G+F +V ++ TG A+K+++K KV K+ IE E + Sbjct: 36 QNTAHLDQFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ V P +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 155 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HS + +R V+DFG + R G T CGTP Y+APE+ Sbjct: 156 EYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEI 210 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + KGY+ A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDL Sbjct: 211 ILSKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 Query: 1193 LHKILDPDPSTRI-----PISRIKKSAWY 1264 L +L D + R ++ IK W+ Sbjct: 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWF 298
>P36887:KAPCA_PIG cAMP-dependent protein kinase, alpha-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 151 bits (382), Expect = 9e-36 Identities = 86/269 (31%), Positives = 141/269 (52%), Gaps = 5/269 (1%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + T + ++E K LG G+F +V ++ TG A+K+++K KV K+ IE E + Sbjct: 36 QNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ V P +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ Sbjct: 96 LQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 155 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HS + +R V+DFG + R G T CGTP Y+APE+ Sbjct: 156 EYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEI 210 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + KGY+ A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDL Sbjct: 211 ILSKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 Query: 1193 LHKILDPDPSTRI-----PISRIKKSAWY 1264 L +L D + R ++ IK W+ Sbjct: 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWF 298
>Q61XD3:AIR2_CAEBR Aurora/Ipl1-related protein kinase 2 - Caenorhabditis briggsae| Length = 302 Score = 151 bits (382), Expect = 9e-36 Identities = 83/283 (29%), Positives = 139/283 (49%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +EIG+ LG+G F VY AR AIK++ K ++ G+ Q++REI + ++HPN Sbjct: 27 FEIGRPLGKGKFGSVYLARTKTGHFHCAIKVLFKSQLISGGVEHQLEREIEIQSHLQHPN 86 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L+ KIY +LEYA GGE++ ++ + + E A +Y +++ A+ YCH + V Sbjct: 87 IIRLYNYFWDAKKIYLILEYAPGGEMYKQLTTQKRFTEAMAGKYMYEIADALSYCHRKNV 146 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR + DFG S A ++ T CGT Y+ PE+++ + Sbjct: 147 IHRDIKPENLLIGAQGELKIGDFGWSVHAPSNKR----QTMCGTMDYLPPEMVNGNSHSD 202 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A D+W+ GV+ + + G PF N + Y I F P + +DL+ K+L D Sbjct: 203 A-VDLWAIGVLCYEFLVGKPPFEHENQADTYSAIKAGRFTYPDFVKKGARDLIGKLLVVD 261 Query: 1217 PSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSV 1345 P R + +K W ++ + E + AE A+S+ Sbjct: 262 PRRRCSLQEVKDHYWVTSMLDSCRRAAEKQ-----KAERAASL 299
>P28178:PK2_DICDI Protein kinase 2 - Dictyostelium discoideum (Slime mold)| Length = 479 Score = 151 bits (381), Expect = 1e-35 Identities = 84/277 (30%), Positives = 142/277 (51%), Gaps = 12/277 (4%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E+ +G+G+F KV + + A+K++ KD + + K E ++++ + HP Sbjct: 153 FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPF 212 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L TK K+Y VL++ GGELF + +EG+ +E + Y +++SA+D+ H + + Sbjct: 213 IVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDI 272 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R ++DFGLS + DG T CGTP Y+APEVL+ G+ G Sbjct: 273 VYRDLKPENILLDSEGHICITDFGLSKKIETT--DGTF-TFCGTPEYLAPEVLNGHGH-G 328 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 D WS G +L+ ++ G PF+ N+ MY++I + K P Y S E K LL +L + Sbjct: 329 CAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLLEGLLTRE 388 Query: 1217 PSTRIPI---SRIKKSAWY---------RRPVEVNAK 1291 R+ +K+ W+ R+ VEV+ K Sbjct: 389 VDKRLGTKGGGEVKQHPWFKNIDWEKLDRKEVEVHFK 425
>P17612:KAPCA_HUMAN cAMP-dependent protein kinase, alpha-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 151 bits (381), Expect = 1e-35 Identities = 86/269 (31%), Positives = 141/269 (52%), Gaps = 5/269 (1%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + T + ++E K LG G+F +V ++ TG A+K+++K KV K+ IE E + Sbjct: 36 QNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ V P +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 155 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HS + +R V+DFG + R G T CGTP Y+APE+ Sbjct: 156 EYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEI 210 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + KGY+ A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDL Sbjct: 211 ILSKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 Query: 1193 LHKILDPDPSTRI-----PISRIKKSAWY 1264 L +L D + R ++ IK W+ Sbjct: 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWF 298
>Q8MJ44:KAPCA_CANFA cAMP-dependent protein kinase, alpha-catalytic subunit - Canis| familiaris (Dog) Length = 350 Score = 151 bits (381), Expect = 1e-35 Identities = 86/269 (31%), Positives = 141/269 (52%), Gaps = 5/269 (1%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + T + ++E K LG G+F +V ++ TG A+K+++K KV K+ IE E + Sbjct: 35 QNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRI 94 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ V P +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ Sbjct: 95 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 154 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HS + +R V+DFG + R G T CGTP Y+APE+ Sbjct: 155 EYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEI 209 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + KGY+ A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDL Sbjct: 210 ILSKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 1193 LHKILDPDPSTRI-----PISRIKKSAWY 1264 L +L D + R ++ IK W+ Sbjct: 269 LRNLLQVDLTKRFGNLKNGVNDIKNHKWF 297
>Q7ZX15:AKT2A_XENLA RAC-beta serine/threonine-protein kinase-A - Xenopus laevis (African| clawed frog) Length = 486 Score = 151 bits (381), Expect = 1e-35 Identities = 97/314 (30%), Positives = 153/314 (48%), Gaps = 3/314 (0%) Frame = +2 Query: 482 ILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 + M ++ K LG+GTF KV R ATG+ A+K++ K+ + + E V++ Sbjct: 152 VTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTLTESRVLQN 211 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 KHP + L T ++ FV+EYA GGELF + +E ED AR Y +++SA++Y Sbjct: 212 TKHPFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYL 271 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 HSR V +R ++DFGL + + T CGTP Y+APEVL Sbjct: 272 HSRNVVYRDIKLENLMLDKDGHVKITDFGL--CKEGITDGATMRTFCGTPEYLAPEVLED 329 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHK 1201 Y G D W GV+++ ++ G LPF+ + ++ I + + PR S E K LL Sbjct: 330 NDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAG 388 Query: 1202 ILDPDPSTRI--PISRIKKSAWYRRPVEVNAKK-TEPEATHTFSAEAASSVSTGCSTSER 1372 +L DP R+ + ++ +R V +N + TE + T F + S + T E Sbjct: 389 LLKKDPKQRLGGGPNDAQEVMSHRFFVSINWQDVTERKLTPPFKPQVTSEIDTRYFDDEF 448 Query: 1373 NQGSLSLPNLNAFD 1414 S++L + +D Sbjct: 449 TAQSITLTPPDRYD 462
>Q39030:KPK19_ARATH Serine/threonine-protein kinase AtPK19 - Arabidopsis thaliana| (Mouse-ear cress) Length = 471 Score = 150 bits (378), Expect = 3e-35 Identities = 88/273 (32%), Positives = 145/273 (53%), Gaps = 5/273 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E+ K +GQG F KVY R T + A+K++ KDK+ + E +K E ++ + HP Sbjct: 140 FEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPF 199 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++QL TK ++Y VL++ GG LF ++ +G ED AR Y +++SA+ + H +G+ Sbjct: 200 IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 259 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG LA ++ ++ CGT Y+APE++ KG+D Sbjct: 260 MHRDLKPENILMDVDGHVMLTDFG---LAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDK 316 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A AD WS G++L+ ++ G PF + ++ ++I K K P++ S E LL +L + Sbjct: 317 A-ADWWSVGILLYEMLTGKPPFLGSK-GKIQQKIVKDKIKLPQFLSNEAHALLKGLLQKE 374 Query: 1217 PSTRI-----PISRIKKSAWYRRPVEVNAKKTE 1300 P R+ IKK W++ +N KK E Sbjct: 375 PERRLGSGPSGAEEIKKHKWFK---AINWKKLE 404
>P25321:KAPCA_CRIGR cAMP-dependent protein kinase, alpha-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 150 bits (378), Expect = 3e-35 Identities = 85/269 (31%), Positives = 140/269 (52%), Gaps = 5/269 (1%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + T + ++ K LG G+F +V ++ TG A+K+++K KV K+ IE E + Sbjct: 36 QNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ V P +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 155 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HS + +R V+DFG + R G T CGTP Y+APE+ Sbjct: 156 EYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEI 210 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + KGY+ A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDL Sbjct: 211 ILSKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 Query: 1193 LHKILDPDPSTRI-----PISRIKKSAWY 1264 L +L D + R ++ IK W+ Sbjct: 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWF 298
>P13185:KIN1_YEAST Protein kinase KIN1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1064 Score = 149 bits (376), Expect = 5e-35 Identities = 87/289 (30%), Positives = 145/289 (50%), Gaps = 28/289 (9%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGL--------------- 622 +G +E + +G G+ KV A++ T + A+K++N+ TK L Sbjct: 117 LGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNR--ATKAFLHKEQMLPPPKNEQDV 174 Query: 623 IEQIK-------------REISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNK 763 +E+ K RE S+ +++ HP++ +LFE+ + Y + EY GG+L + Sbjct: 175 LERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDY 234 Query: 764 IVKEGKLNEDAARRYFHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALA 943 I++ G + E AR++ + SA+ Y H+ + HR + DFGLS + Sbjct: 235 IIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIY 294 Query: 944 DCARQDGLLHTTCGTPAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIE 1123 D +Q LHT CG+ + APE+L Y G + DVWS GV+LFVLV G +PF + N Sbjct: 295 DSRKQ---LHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSV 351 Query: 1124 MYRRISKADFKCPRYFSAELKDLLHKILDPDPSTRIPISRIKKSAWYRR 1270 ++ +I + + P++ S E+ LL K+L DP R + ++ + W R Sbjct: 352 LHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVR 400
>Q7TNJ7:KCC1G_RAT Calcium/calmodulin-dependent protein kinase type 1G - Rattus| norvegicus (Rat) Length = 476 Score = 149 bits (376), Expect = 5e-35 Identities = 83/256 (32%), Positives = 137/256 (53%), Gaps = 7/256 (2%) Frame = +2 Query: 515 LGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPNVLQLFE 694 LG G F++V+ + TG+ A+K I K + +E EI+V++ +KH N++ L + Sbjct: 29 LGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLEN---EIAVLKRIKHENIVTLED 85 Query: 695 VMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGVYHR--- 865 + + + Y V++ GGELF++I++ G E A Q++SA+ Y H G+ HR Sbjct: 86 IYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLK 145 Query: 866 XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDGAKA 1045 ++DFGLS + Q+G++ T CGTP YVAPEVL++K Y A Sbjct: 146 PENLLYLTPEENSKIMITDFGLSKM----EQNGVMSTACGTPGYVAPEVLAQKPYSKA-V 200 Query: 1046 DVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLLHKILDP 1213 D WS GVI ++L+ GY PF+E +++ +I + +F+ P + S KD + +L+ Sbjct: 201 DCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEK 260 Query: 1214 DPSTRIPISRIKKSAW 1261 DP+ R + + W Sbjct: 261 DPNERYTCEKALRHPW 276
>Q91VB2:KCC1G_MOUSE Calcium/calmodulin-dependent protein kinase type 1G - Mus musculus| (Mouse) Length = 477 Score = 149 bits (376), Expect = 5e-35 Identities = 83/256 (32%), Positives = 137/256 (53%), Gaps = 7/256 (2%) Frame = +2 Query: 515 LGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPNVLQLFE 694 LG G F++V+ + TG+ A+K I K + +E EI+V++ +KH N++ L + Sbjct: 29 LGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLEN---EIAVLKRIKHENIVTLED 85 Query: 695 VMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGVYHR--- 865 + + + Y V++ GGELF++I++ G E A Q++SA+ Y H G+ HR Sbjct: 86 IYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLK 145 Query: 866 XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDGAKA 1045 ++DFGLS + Q+G++ T CGTP YVAPEVL++K Y A Sbjct: 146 PENLLYLTPEENSKIMITDFGLSKM----EQNGVMSTACGTPGYVAPEVLAQKPYSKA-V 200 Query: 1046 DVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLLHKILDP 1213 D WS GVI ++L+ GY PF+E +++ +I + +F+ P + S KD + +L+ Sbjct: 201 DCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEK 260 Query: 1214 DPSTRIPISRIKKSAW 1261 DP+ R + + W Sbjct: 261 DPNERYTCEKALRHPW 276
>Q8N568:DCLK2_HUMAN Serine/threonine-protein kinase DCLK2 - Homo sapiens (Human)| Length = 766 Score = 149 bits (376), Expect = 5e-35 Identities = 91/278 (32%), Positives = 147/278 (52%), Gaps = 10/278 (3%) Frame = +2 Query: 458 DRMDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIK 637 +R E T+L +Y+IGK +G G FA V + +TG+ A+K+I+K K G I+ Sbjct: 382 NRCSESSTLLE-KYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCC--GKEHLIE 438 Query: 638 REISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQ 817 E+S++R VKHPN++ L E M T ++++ V+E KGG+LF+ I K E + Sbjct: 439 NEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYN 498 Query: 818 LISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVS----DFGLSALADCARQDGLLHTTCG 985 L +A+ Y H + HR S DFGL+ + +G L+T CG Sbjct: 499 LANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV-----EGPLYTVCG 553 Query: 986 TPAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLI--EMYRRI--SKADF 1153 TP YVAPE+++ GY G K D+W++GVI ++L+ G+ PF N + +++ +I K +F Sbjct: 554 TPTYVAPEIIAETGY-GLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEF 612 Query: 1154 KCPRY--FSAELKDLLHKILDPDPSTRIPISRIKKSAW 1261 P + + K+L+ ++L + R +I W Sbjct: 613 PAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPW 650
>P05132:KAPCA_MOUSE cAMP-dependent protein kinase, alpha-catalytic subunit - Mus musculus| (Mouse) Length = 351 Score = 149 bits (375), Expect = 6e-35 Identities = 84/269 (31%), Positives = 141/269 (52%), Gaps = 5/269 (1%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + T + +++ K LG G+F +V ++ +G A+K+++K KV K+ IE E + Sbjct: 36 QNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ V P +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 155 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HS + +R V+DFG + R G T CGTP Y+APE+ Sbjct: 156 EYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEI 210 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + KGY+ A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDL Sbjct: 211 ILSKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 Query: 1193 LHKILDPDPSTRI-----PISRIKKSAWY 1264 L +L D + R ++ IK W+ Sbjct: 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWF 298
>Q8BWQ5:DCLK3_MOUSE Serine/threonine-protein kinase DCLK3 - Mus musculus (Mouse)| Length = 619 Score = 149 bits (375), Expect = 6e-35 Identities = 90/280 (32%), Positives = 148/280 (52%), Gaps = 10/280 (3%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y+IG +G G FA V R+ T QA A+KMI+K ++ G + + EI +++ + HPN Sbjct: 343 YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDKSQLK--GKEDIVDSEILIIQSLSHPN 400 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L EV T+++IY ++EY +GG+LF+ IV+ K E A L A+ + H + + Sbjct: 401 IVKLHEVYETEAEIYLIMEYVQGGDLFDAIVENVKFPEPEAAVMITDLCKALVHMHDKNI 460 Query: 857 YHRXXXXXXXXXXXXXXXXV----SDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 HR + +DFGL+ + T CGTP YVAPE+LS K Sbjct: 461 VHRDVKPENLLVQRNEDKSITLKLADFGLAKYVVRP-----IFTVCGTPTYVAPEILSEK 515 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFH--ETNLIEMYR--RISKADFKCPRY--FSAELK 1186 GY G + D+W++GVIL++L+ G+ PF E + E++ ++ + +F P + S K Sbjct: 516 GY-GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAK 574 Query: 1187 DLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPE 1306 DL+ +L+ DP R ++ + W N ++ E Sbjct: 575 DLVRNLLEVDPKKRYTAEQVLQHPWIEMVGHTNTGNSQKE 614
>Q6DE87:CHK1_XENLA Serine/threonine-protein kinase Chk1 - Xenopus laevis (African clawed| frog) Length = 474 Score = 149 bits (375), Expect = 6e-35 Identities = 86/270 (31%), Positives = 145/270 (53%), Gaps = 3/270 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +++ + LG+G + +V A N T +AVA+K++ D E IK+EI + R++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIV--DMTRAADCPENIKKEICINRMLSHTN 66 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++ + + Y LEY +GGELF++I + + E A+++F QLI+ ++Y HS G+ Sbjct: 67 IVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHSIGI 126 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR +SDFGL+ + ++ LL+ CGT YVAPE++ + + Sbjct: 127 THRDIKPENLLLDERDQLKISDFGLATVFRHNGKERLLNKMCGTLPYVAPELIKSRAFHA 186 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLI--EMYRRISKADFKCP-RYFSAELKDLLHKIL 1207 DVWS G++L ++AG LP+ + N + E K + P + SA LL K+L Sbjct: 187 DPVDVWSCGIVLTAMLAGELPWDQPNEVCQEYCDWKEKNHYLTPWKKISATPLALLCKML 246 Query: 1208 DPDPSTRIPISRIKKSAWYRRPVEVNAKKT 1297 +P +RI I IKK W+ ++ K++ Sbjct: 247 TENPQSRITIPDIKKDRWFTEIIKKGLKRS 276
>O54863:TSSK2_MOUSE Testis-specific serine/threonine-protein kinase 2 - Mus musculus| (Mouse) Length = 357 Score = 148 bits (374), Expect = 8e-35 Identities = 93/308 (30%), Positives = 155/308 (50%), Gaps = 5/308 (1%) Frame = +2 Query: 464 MDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQ-IKR 640 MD+ + Y +G LG+G++AKV A + VA+K+I++ K T +E+ + R Sbjct: 1 MDDAAVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKK-TPTDFVERFLPR 59 Query: 641 EISVMRLVKHPNVLQLFEVMATKS-KIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQ 817 E+ ++ V H ++++ +E+ T +IY V+E G+L I G L+ED + F Q Sbjct: 60 EMDILATVNHRSIIKTYEIFETSDGRIYIVMELGVQGDLLTFIKCRGALHEDVGGKMFRQ 119 Query: 818 LISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLS--ALADCARQDGLLHTTCGTP 991 + SA+ YCH V HR +SDFG S L D + + L T CG+ Sbjct: 120 VSSAVKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKGCLRDGSGRIVLSKTFCGSA 179 Query: 992 AYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEM-YRRISKADFKCPRY 1168 AY APEV Y D+WS GVIL+++V G +P+ ++++ ++ ++ + DF + Sbjct: 180 AYAAPEVRQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIKKLRIQKEHRVDFPRSKN 239 Query: 1169 FSAELKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVS 1348 + E KDL+++IL PD + R+ I I +W + P K + ++ +F E Sbjct: 240 LTGECKDLIYRILQPDVNRRLHIDEILSHSWLQPP------KPKAMSSASFKREGEGKYR 293 Query: 1349 TGCSTSER 1372 C R Sbjct: 294 ADCKLDTR 301
>Q96NX5:KCC1G_HUMAN Calcium/calmodulin-dependent protein kinase type 1G - Homo sapiens| (Human) Length = 476 Score = 148 bits (374), Expect = 8e-35 Identities = 83/256 (32%), Positives = 136/256 (53%), Gaps = 7/256 (2%) Frame = +2 Query: 515 LGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPNVLQLFE 694 LG G F++V+ + TG+ A+K I K + +E EI+V++ +KH N++ L + Sbjct: 29 LGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLEN---EIAVLKKIKHENIVTLED 85 Query: 695 VMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGVYHR--- 865 + + + Y V++ GGELF++I++ G E A Q++SA+ Y H G+ HR Sbjct: 86 IYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLK 145 Query: 866 XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDGAKA 1045 ++DFGLS + Q+G++ T CGTP YVAPEVL++K Y A Sbjct: 146 PENLLYLTPEENSKIMITDFGLSKM----EQNGIMSTACGTPGYVAPEVLAQKPYSKA-V 200 Query: 1046 DVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLLHKILDP 1213 D WS GVI ++L+ GY PF+E +++ +I + +F+ P + S KD + +L+ Sbjct: 201 DCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEK 260 Query: 1214 DPSTRIPISRIKKSAW 1261 DP+ R + W Sbjct: 261 DPNERYTCEKALSHPW 276
>P27791:KAPCA_RAT cAMP-dependent protein kinase, alpha-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 148 bits (374), Expect = 8e-35 Identities = 84/269 (31%), Positives = 140/269 (52%), Gaps = 5/269 (1%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + T + ++ K LG G+F +V ++ +G A+K+++K KV K+ IE E + Sbjct: 36 QNTAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ V P +++L S +Y V+EY GGE+F+ + + G+ +E AR Y Q++ Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 155 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HS + +R V+DFG + R G T CGTP Y+APE+ Sbjct: 156 EYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEI 210 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + KGY+ A D W+ GV+++ + AGY PF I++Y +I + P +FS++LKDL Sbjct: 211 ILSKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 Query: 1193 LHKILDPDPSTRI-----PISRIKKSAWY 1264 L +L D + R ++ IK W+ Sbjct: 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWF 298
>Q6PGN3:DCLK2_MOUSE Serine/threonine-protein kinase DCLK2 - Mus musculus (Mouse)| Length = 756 Score = 148 bits (373), Expect = 1e-34 Identities = 90/269 (33%), Positives = 140/269 (52%), Gaps = 10/269 (3%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L+ +Y IGK +G G FA V + TG+ A+K+I+K K G I+ E+S++R V Sbjct: 389 LLEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCC--GKEHLIENEVSILRRV 446 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 KHPN++ L E M T + ++ V+E KGG+LF+ I K E + L +A+ Y H Sbjct: 447 KHPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLH 506 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVS----DFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 S + HR S DFGL+ + +G L+T CGTP YVAPE+ Sbjct: 507 SLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV-----EGPLYTVCGTPTYVAPEI 561 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLI--EMYRRI--SKADFKCPRY--FS 1174 ++ GY G K DVW++GVI ++L+ G+ PF N + +++ +I K +F P + + Sbjct: 562 IAETGY-GLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNIT 620 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAW 1261 K+L+ ++L + R I W Sbjct: 621 DSAKELISQMLQVNVEARCTAGEILSHPW 649
>Q0GGW5:STK11_CHICK Serine/threonine protein kinase 11 - Gallus gallus (Chicken)| Length = 440 Score = 147 bits (372), Expect = 1e-34 Identities = 86/272 (31%), Positives = 145/272 (53%), Gaps = 6/272 (2%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIE-QIKREIS 649 +R L+G+Y +G LG+G++ KV + T A+K++ K K+ ++ E +K+EI Sbjct: 41 KRAKLIGKYLMGDLLGEGSYGKVKEMLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQ 100 Query: 650 VMRLVKHPNVLQLFEVMAT--KSKIYFVLEYAKGG--ELFNKIVKEGKLNEDAARRYFHQ 817 ++R ++H NV+QL +V+ K K+Y V+EY G E+ + V E + A YF Q Sbjct: 101 LLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDS-VPEKRFPVFQAHGYFCQ 159 Query: 818 LISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAY 997 LI ++Y HS+G+ H+ +SD G++ +D T+ G+PA+ Sbjct: 160 LIDGLEYLHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAEDDTCRTSQGSPAF 219 Query: 998 VAPEVLSRKG-YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFS 1174 PE+ + + G K D+WS+GV L+ + G PF N+ +++ I K DF P Sbjct: 220 QPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGDFTIPEDCG 279 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAWYRR 1270 L DLL +L+ DP+ R I +I++ W+R+ Sbjct: 280 PPLSDLLRGMLEYDPAKRFSIQQIRQHNWFRK 311
>O59697:PPK25_SCHPO Serine/threonine-protein kinase ppk25 - Schizosaccharomyces pombe| (Fission yeast) Length = 423 Score = 147 bits (372), Expect = 1e-34 Identities = 83/262 (31%), Positives = 137/262 (52%), Gaps = 1/262 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G + I K +G G+ KV N+ TG+ A+KMI +++RE + RL++ Sbjct: 50 VGNWIIKKTIGAGSMGKVKLVVNILTGEKAALKMIPFTP-NNTSQTVRVQREALLGRLLR 108 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+ ++ + + T + Y + EY GG+L I+ GKL+ED AR + QLI+A+ Y H Sbjct: 109 HPNICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYLHK 168 Query: 848 RGVYHRXXXXXXXXXXXXXXXX-VSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 + HR + DFGLS +D LL T CG+ + APE+L K Sbjct: 169 NFIVHRDLKIENVLLTQDSRQVKLIDFGLSNFYS---KDDLLRTYCGSLYFAAPELLDAK 225 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 Y G + DVWS GV+++V+V G +PF + ++ ++ +I + P Y S + L+ + Sbjct: 226 PYIGPEVDVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPSYISEDCCSLIAAM 285 Query: 1205 LDPDPSTRIPISRIKKSAWYRR 1270 L+ +P R + + K W ++ Sbjct: 286 LNVNPRKRCSLEQAAKFPWLKK 307
>P06244:KAPA_YEAST cAMP-dependent protein kinase type 1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 397 Score = 147 bits (372), Expect = 1e-34 Identities = 73/265 (27%), Positives = 146/265 (55%), Gaps = 5/265 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 ++I + LG G+F +V+ R+ G+ A+K++ K+ V ++ +E E ++ +V HP Sbjct: 87 FQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPF 146 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++++ +I+ +++Y +GGELF+ + K + A+ Y ++ A++Y HS+ + Sbjct: 147 IIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDI 206 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R ++DFG + + +T CGTP Y+APEV+S K Y+ Sbjct: 207 IYRDLKPENILLDKNGHIKITDFGFAKYV-----PDVTYTLCGTPDYIAPEVVSTKPYN- 260 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 D WS G++++ ++AGY PF+++N ++ Y +I A+ + P +F+ ++KDLL +++ D Sbjct: 261 KSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRD 320 Query: 1217 PSTRI-----PISRIKKSAWYRRPV 1276 S R+ +K W++ V Sbjct: 321 LSQRLGNLQNGTEDVKNHPWFKEVV 345
>O15075:DCLK1_HUMAN Serine/threonine-protein kinase DCLK1 - Homo sapiens (Human)| Length = 740 Score = 147 bits (371), Expect = 2e-34 Identities = 89/266 (33%), Positives = 136/266 (51%), Gaps = 10/266 (3%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 RY++G+ +G G FA V +T + A+K+I K K G I+ E+S++R VKHP Sbjct: 389 RYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCR--GKEHMIQNEVSILRRVKHP 446 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 N++ L E M +++Y V+E KGG+LF+ I K E A + L SAI Y HS Sbjct: 447 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLN 506 Query: 854 VYHRXXXXXXXXXXXXXXXXVS----DFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 + HR S DFGL+ + DG L+T CGTP YVAPE+++ Sbjct: 507 IVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV-----DGPLYTVCGTPTYVAPEIIAE 561 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFH----ETNLIEMYRRISKADFKCPRY--FSAEL 1183 GY G K D+W++GVI ++L+ G+ PF + ++ + + DF P + S Sbjct: 562 TGY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSA 620 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAW 1261 K+L+ +L D R ++ + W Sbjct: 621 KELITMMLLVDVDQRFSAVQVLEHPW 646
>Q6BVA0:IPL1_DEBHA Spindle assembly checkpoint kinase - Debaryomyces hansenii (Yeast)| (Torulaspora hansenii) Length = 412 Score = 147 bits (370), Expect = 2e-34 Identities = 77/262 (29%), Positives = 134/262 (51%) Frame = +2 Query: 476 RTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVM 655 R + + +EIGK LG+G KVY ++ +G A+K++ K + + L + +REI + Sbjct: 141 RHMTLDDFEIGKVLGKGKLGKVYCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIEIQ 200 Query: 656 RLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAID 835 + HP + +L+ +Y +LEY+ GEL++ + + + N+ A Y +Q+ A+D Sbjct: 201 SNLIHPKISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALD 260 Query: 836 YCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVL 1015 Y H++ + HR +SDFG S + + L T CGT Y+ PE++ Sbjct: 261 YLHTKHIIHRDIKPENILLSTDNCIKLSDFGWSVKSLPSSSTKRL-TICGTLDYLPPEMI 319 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLL 1195 +D D+WS G++ + + G PF E + Y+RI+K D K P + S+E DL+ Sbjct: 320 ESNEHD-YTVDIWSLGILCYEFLVGKPPFEEIDKNSTYKRIAKVDLKIPSFLSSEATDLI 378 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 ++L P RI ++ + W Sbjct: 379 LRLLQKSPKKRITLAEVMNHPW 400
>Q9C098:DCLK3_HUMAN Serine/threonine-protein kinase DCLK3 - Homo sapiens (Human)| Length = 648 Score = 147 bits (370), Expect = 2e-34 Identities = 92/282 (32%), Positives = 148/282 (52%), Gaps = 10/282 (3%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YE G+ +G G FA V R+ T QA A+K+I+K ++ G + + EI +++ + HPN Sbjct: 356 YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLK--GKEDMVDSEILIIQSLSHPN 413 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L EV T +IY +LEY +GG+LF+ I++ K E A L A+ + H + + Sbjct: 414 IVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSI 473 Query: 857 YHR----XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 HR ++DFGL+ R + T CGTP YVAPE+LS K Sbjct: 474 VHRDLKPENLLVQRNEDKSTTLKLADFGLA--KHVVRP---IFTVCGTPTYVAPEILSEK 528 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFH--ETNLIEMYRRISKADFK-CPRYF---SAELK 1186 GY G + D+W++GVIL++L+ G+ PF E + E++ I F+ P Y+ S K Sbjct: 529 GY-GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAK 587 Query: 1187 DLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEAT 1312 DL+ ++L DP R ++ + W + N K + + + Sbjct: 588 DLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKRQKQVS 629
>O08875:DCLK1_RAT Serine/threonine-protein kinase DCLK1 - Rattus norvegicus (Rat)| Length = 433 Score = 146 bits (369), Expect = 3e-34 Identities = 88/266 (33%), Positives = 137/266 (51%), Gaps = 10/266 (3%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 RY++G+ +G G FA V +T + A+K+I K K G I+ E+S++R VKHP Sbjct: 82 RYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCR--GKEHMIQNEVSILRRVKHP 139 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 N++ L E M +++Y V+E KGG+LF+ I K E A + L SAI Y HS Sbjct: 140 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLN 199 Query: 854 VYHRXXXXXXXXXXXXXXXXVS----DFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 + HR S DFGL+ + DG L+T CGTP YVAPE+++ Sbjct: 200 IVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV-----DGPLYTVCGTPTYVAPEIIAE 254 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFH----ETNLIEMYRRISKADFKCPRY--FSAEL 1183 GY G K D+W++GVI ++L+ G+ PF + ++ + + DF P + S Sbjct: 255 TGY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSA 313 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAW 1261 K+L++ +L + R ++ + W Sbjct: 314 KELINMMLLVNVDQRFSAVQVLEHPW 339
>Q9JLM8:DCLK1_MOUSE Serine/threonine-protein kinase DCLK1 - Mus musculus (Mouse)| Length = 756 Score = 146 bits (369), Expect = 3e-34 Identities = 88/266 (33%), Positives = 137/266 (51%), Gaps = 10/266 (3%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 RY++G+ +G G FA V +T + A+K+I K K G I+ E+S++R VKHP Sbjct: 405 RYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCR--GKEHMIQNEVSILRRVKHP 462 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 N++ L E M +++Y V+E KGG+LF+ I K E A + L SAI Y HS Sbjct: 463 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLN 522 Query: 854 VYHRXXXXXXXXXXXXXXXXVS----DFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 + HR S DFGL+ + DG L+T CGTP YVAPE+++ Sbjct: 523 IVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV-----DGPLYTVCGTPTYVAPEIIAE 577 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFH----ETNLIEMYRRISKADFKCPRY--FSAEL 1183 GY G K D+W++GVI ++L+ G+ PF + ++ + + DF P + S Sbjct: 578 TGY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSA 636 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAW 1261 K+L++ +L + R ++ + W Sbjct: 637 KELINMMLLVNVDQRFSAVQVLEHPW 662
>Q9URY1:PPK16_SCHPO Serine/threonine-protein kinase ppk16 - Schizosaccharomyces pombe| (Fission yeast) Length = 672 Score = 146 bits (368), Expect = 4e-34 Identities = 88/263 (33%), Positives = 136/263 (51%), Gaps = 3/263 (1%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y I +G+G+F KVY A +L T K++ K K +I + REI R + Sbjct: 28 VGTYRIESVVGEGSFGKVYLAAHLLTNT----KVVLKSSCRKQAII--LAREIHHHRRLL 81 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN+ +L+EV+ T+ +IY +EY GEL++ + +E +L+E R QL AI Y H Sbjct: 82 HPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQLCCAIQYLHR 141 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 +G HR + DFG S +DC+R+ ++T CGT AY APE++ Sbjct: 142 QGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRRT-FMNTRCGTVAYCAPELVQGHK 200 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRY---FSAELKDLLH 1198 Y G D+WS G+I++ L+ G LPF E ++ ++I +CP+Y S LL Sbjct: 201 YIGECVDIWSLGIIMYALLIGRLPFDEDDVSLTEQKIIN---ECPQYPETLSKNSSSLLK 257 Query: 1199 KILDPDPSTRIPISRIKKSAWYR 1267 +L D R I +I +++ Sbjct: 258 SLLCKDYRLRPSIDQIISHPYFK 280
>P05986:KAPC_YEAST cAMP-dependent protein kinase type 3 - Saccharomyces cerevisiae| (Baker's yeast) Length = 398 Score = 146 bits (368), Expect = 4e-34 Identities = 75/267 (28%), Positives = 139/267 (52%) Frame = +2 Query: 431 VCFTPFR*LDRMDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVT 610 +C L D + ++I + LG G+F +V+ R+ G+ A+K + K + Sbjct: 66 ICLVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIV 125 Query: 611 KVGLIEQIKREISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNE 790 K+ +E E ++ +V HP +++++ +++ V++Y +GGELF+ + K + Sbjct: 126 KLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPN 185 Query: 791 DAARRYFHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLL 970 A+ Y ++ A++Y HS+ + +R ++DFG + + Sbjct: 186 PVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV-----PDVT 240 Query: 971 HTTCGTPAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKAD 1150 +T CGTP Y+APEV+S K Y+ D WS GV+++ ++AGY PF+ +N ++ Y I A+ Sbjct: 241 YTLCGTPDYIAPEVVSTKPYN-KSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAE 299 Query: 1151 FKCPRYFSAELKDLLHKILDPDPSTRI 1231 K P +F + +DLL K++ D S R+ Sbjct: 300 LKFPPFFHPDAQDLLKKLITRDLSERL 326
>Q09170:CDS1_SCHPO Serine/threonine-protein kinase cds1 - Schizosaccharomyces pombe| (Fission yeast) Length = 460 Score = 146 bits (368), Expect = 4e-34 Identities = 94/326 (28%), Positives = 161/326 (49%), Gaps = 17/326 (5%) Frame = +2 Query: 422 VGFVCFTPFR*LDRMDERRTILMGR---YEIGKQLGQGTFAKVYYARNLATGQAVAIKMI 592 + F+C P + D ++ ++ YEI + LG GTFA V A + +G+ AIK+I Sbjct: 141 ISFLCQVPVK--HSRDSQKNMIKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKII 198 Query: 593 NKDKV----TKVGLIEQIKREISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFN 760 NK K+ ++ E +REI +++ + HP V+Q E+ +++ V+EY +GG+L + Sbjct: 199 NKRKILLTSSEKRATEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMD 258 Query: 761 KIVKEGKLNEDAARRYFHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSAL 940 ++ G ++E + QL+ + + H +GV HR +SDFGL+ + Sbjct: 259 FLIANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKV 318 Query: 941 ADCARQDGLLHTTCGTPAYVAPEVLSRK------GYDGAKADVWSSGVILFVLVAGYLPF 1102 L T CGT Y+APEVL K GYD K D+WS G +L+V++ +PF Sbjct: 319 IH--GTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDD-KVDIWSLGCVLYVMLTASIPF 375 Query: 1103 HETNLIEMYRRISKADFKCPRYFSAELK----DLLHKILDPDPSTRIPISRIKKSAWYRR 1270 ++ + ISK + E+ DL++++L+ +P RI S + W+ Sbjct: 376 ASSSQAKCIELISKGAYPIEPLLENEISEEGIDLINRMLEINPEKRISESEALQHPWF-Y 434 Query: 1271 PVEVNAKKTEPEATHTFSAEAASSVS 1348 V + +T P ++ + E +S S Sbjct: 435 TVSTHEHRTPPSSSEHEATEQLNSSS 460
>Q9M077:AUR1_ARATH Serine/threonine-protein kinase Aurora-1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 294 Score = 146 bits (368), Expect = 4e-34 Identities = 81/257 (31%), Positives = 133/257 (51%), Gaps = 2/257 (0%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 ++IGK LG+G F VY AR + VA+K++ K ++ + + Q++RE+ + ++HPN Sbjct: 31 FDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQLQQSQVEHQLRREVEIQSHLRHPN 90 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +L+L+ + ++Y +LEYA GEL+ + K +E A Y L A+ YCH + V Sbjct: 91 ILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATYVASLARALIYCHGKHV 150 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG S R+ T CGT Y+ PE++ +D Sbjct: 151 IHRDIKPENLLIGAQGELKIADFGWSVHTFNRRR-----TMCGTLDYLPPEMVESVEHD- 204 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCP--RYFSAELKDLLHKILD 1210 A D+WS G++ + + G PF + YRRI + D K P SA KDL+ ++L Sbjct: 205 ASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISASAKDLISQMLV 264 Query: 1211 PDPSTRIPISRIKKSAW 1261 + S R+P+ ++ + W Sbjct: 265 KESSQRLPLHKLLEHPW 281
>Q6IP76:AKT2B_XENLA RAC-beta serine/threonine-protein kinase-B - Xenopus laevis (African| clawed frog) Length = 485 Score = 146 bits (368), Expect = 4e-34 Identities = 85/253 (33%), Positives = 127/253 (50%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 R + M ++ K LG+GTF KV R ATG A+K++ K+ + + E V Sbjct: 148 RPKVTMNDFDYLKLLGKGTFGKVILVREKATGLYYAMKILRKEVIIAKDEVAHTLTESRV 207 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ KHP + L T ++ FV+EYA GGELF + +E ED AR Y +++SA+ Sbjct: 208 LQNTKHPFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSAL 267 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HSR V +R ++DFGL + + T CGTP Y+APEV Sbjct: 268 EYLHSRNVVYRDIKLENLMLDKDGHVKITDFGL--CKEGITDGATMRTFCGTPEYLAPEV 325 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 L Y G D W GV+++ ++ G LPF+ + ++ I + + PR S E K L Sbjct: 326 LEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEETRFPRTLSPEAKSL 384 Query: 1193 LHKILDPDPSTRI 1231 L +L DP R+ Sbjct: 385 LAGLLKKDPKQRL 397
>P12370:KAPC_DROME cAMP-dependent protein kinase catalytic subunit - Drosophila| melanogaster (Fruit fly) Length = 353 Score = 145 bits (367), Expect = 5e-34 Identities = 84/273 (30%), Positives = 139/273 (50%), Gaps = 5/273 (1%) Frame = +2 Query: 461 RMDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKR 640 R + T + +E K LG G+F +V ++ T A+K+++K KV K+ +E Sbjct: 34 RRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLN 93 Query: 641 EISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQL 820 E +++ ++ P ++ L S +Y VLEY GGE+F+ + K G+ +E +R Y Q+ Sbjct: 94 EKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQI 153 Query: 821 ISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYV 1000 + A +Y H + +R V+DFG + R G T CGTP Y+ Sbjct: 154 VLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFA-----KRVKGRTWTLCGTPEYL 208 Query: 1001 APEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAE 1180 APE++ KGY+ A D W+ GV+++ + AGY PF I++Y +I + P +F ++ Sbjct: 209 APEIILSKGYNKA-VDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSD 267 Query: 1181 LKDLLHKILDPDPSTR-----IPISRIKKSAWY 1264 LKDLL +L D + R ++ IK W+ Sbjct: 268 LKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWF 300
>P21137:KAPC_CAEEL cAMP-dependent protein kinase catalytic subunit - Caenorhabditis| elegans Length = 404 Score = 145 bits (367), Expect = 5e-34 Identities = 82/269 (30%), Positives = 139/269 (51%), Gaps = 5/269 (1%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + T + ++ K LG G+F +V ++ +G A+K+++K KV K+ +E E + Sbjct: 73 QNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRI 132 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ + P ++ + S +Y VLE+ GGE+F+ + + G+ +E +R Y Q++ A Sbjct: 133 LQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAF 192 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HS + +R ++DFG + R G T CGTP Y+APE+ Sbjct: 193 EYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFA-----KRVKGRTWTLCGTPEYLAPEI 247 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + KGY+ A D W+ GV+++ + AGY PF I++Y +I K P +FS ELKDL Sbjct: 248 ILSKGYNKA-VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDL 306 Query: 1193 LHKILDPDPSTRI-----PISRIKKSAWY 1264 L +L D + R ++ IK W+ Sbjct: 307 LKNLLQVDLTKRYGNLKNGVADIKNHKWF 335
>P22612:KAPCG_HUMAN cAMP-dependent protein kinase, gamma-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 145 bits (367), Expect = 5e-34 Identities = 86/283 (30%), Positives = 143/283 (50%), Gaps = 7/283 (2%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + T ++E + LG G+F +V R+ TG A+K++NK KV K+ +E I E + Sbjct: 36 QNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRI 95 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ + P +++L S +Y V+EY GGE+F+++ + G+ +E A Y Q++ A+ Sbjct: 96 LQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAV 155 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 Y HS + HR V+DFG + R G T CGTP Y+APE+ Sbjct: 156 QYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEI 210 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 + KGY+ A D W+ GV+++ + G+ PF+ I++Y +I + P S++LK L Sbjct: 211 ILSKGYNKA-VDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHL 269 Query: 1193 LHKILDPDPSTRI-----PISRIKKSAWYRRP--VEVNAKKTE 1300 L +L D + R + IK W+ + + KK E Sbjct: 270 LRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVE 312
>Q924X7:STK33_MOUSE Serine/threonine-protein kinase 33 - Mus musculus (Mouse)| Length = 491 Score = 145 bits (366), Expect = 7e-34 Identities = 86/268 (32%), Positives = 141/268 (52%), Gaps = 13/268 (4%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y G+ LGQG+F V+ A + TG AIK +NK+K + + ++RE+S+++ V H + Sbjct: 111 YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSSAM-KLLEREVSILKTVNHQH 169 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L +V + K+Y V+E + GEL + + G +E+ R L SAI Y H++ + Sbjct: 170 IIHLEQVFESPQKMYLVMELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKDI 229 Query: 857 YHR---------XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 HR V+DFGLS +R +G++ TTCGTP Y+APE Sbjct: 230 VHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPE 289 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKAD--FKCPRY--FSA 1177 V++ Y + D+WS GVI+F+L+ G PF + ++Y I K + F+ P + S Sbjct: 290 VINAHDY-SQQCDIWSIGVIMFILLCGEPPFLANSEEKLYELIKKGELRFENPVWESVSD 348 Query: 1178 ELKDLLHKILDPDPSTRIPISRIKKSAW 1261 K+ L +++ DP+ RI + + W Sbjct: 349 SAKNTLKQLMKVDPAHRITAKELLDNQW 376
>P34099:KAPC_DICDI cAMP-dependent protein kinase catalytic subunit - Dictyostelium| discoideum (Slime mold) Length = 648 Score = 145 bits (366), Expect = 7e-34 Identities = 73/255 (28%), Positives = 131/255 (51%), Gaps = 5/255 (1%) Frame = +2 Query: 515 LGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPNVLQLFE 694 LG GTF KVY +N G A+K +NK V ++ +E + E S++ + HP ++ L++ Sbjct: 342 LGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVNLYQ 401 Query: 695 VMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGVYHRXXX 874 + K+Y + EY GGE+F + K K + A+ Y +++ A+++ H + + +R Sbjct: 402 AFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQNIVYRDLK 461 Query: 875 XXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDGAKADVW 1054 ++DFG + R + T CGTP Y+APE++ KG+ G D W Sbjct: 462 PENLLIDNQGHIKITDFGFA-----KRVEDRTFTLCGTPEYLAPEIIQSKGH-GKAVDWW 515 Query: 1055 SSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPDPSTRIP 1234 + G+++F ++AGY PF++ + +Y +I P F + KDL+ ++L D + R+ Sbjct: 516 ALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRLLTADRTRRLG 575 Query: 1235 ISR-----IKKSAWY 1264 + +K W+ Sbjct: 576 ALKDGALDVKNHRWF 590
>P06245:KAPB_YEAST cAMP-dependent protein kinase type 2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 380 Score = 145 bits (366), Expect = 7e-34 Identities = 74/245 (30%), Positives = 136/245 (55%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 ++I + LG G+F +V+ R++ G+ AIK++ K +V K+ +E E +++LV+HP Sbjct: 70 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPF 129 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++++ I+ V++Y +GGELF+ + K + A+ Y ++I A++Y H+ + Sbjct: 130 LIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNI 189 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R ++DFG + + T CGTP Y+APEV++ K Y+ Sbjct: 190 IYRDLKPENILLDRNGHIKITDFGFA-----KEVQTVTWTLCGTPDYIAPEVITTKPYN- 243 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 D WS GV+++ ++AGY PF++T ++ Y +I + P YF ++ DLL K++ D Sbjct: 244 KSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITAD 303 Query: 1217 PSTRI 1231 + RI Sbjct: 304 LTRRI 308
>Q60823:AKT2_MOUSE RAC-beta serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 481 Score = 145 bits (366), Expect = 7e-34 Identities = 85/255 (33%), Positives = 130/255 (50%), Gaps = 2/255 (0%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 R + M ++ K LG+GTF KV R ATG+ A+K++ K+ + + E V Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ +HP + L T ++ FV+EYA GGELF + +E ED AR Y +++SA+ Sbjct: 204 LQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSAL 263 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGL--SALADCARQDGLLHTTCGTPAYVAP 1006 +Y HSR V +R ++DFGL ++D A + T CGTP Y+AP Sbjct: 264 EYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGA----TMKTFCGTPEYLAP 319 Query: 1007 EVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELK 1186 EVL Y G D W GV+++ ++ G LPF+ + ++ I + + PR E K Sbjct: 320 EVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAK 378 Query: 1187 DLLHKILDPDPSTRI 1231 LL +L DP R+ Sbjct: 379 SLLAGLLKKDPKQRL 393
>P31751:AKT2_HUMAN RAC-beta serine/threonine-protein kinase - Homo sapiens (Human)| Length = 481 Score = 145 bits (366), Expect = 7e-34 Identities = 85/255 (33%), Positives = 131/255 (51%), Gaps = 2/255 (0%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 R + M ++ K LG+GTF KV R ATG+ A+K++ K+ + + E V Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ +HP + L T ++ FV+EYA GGELF + +E E+ AR Y +++SA+ Sbjct: 204 LQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSAL 263 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGL--SALADCARQDGLLHTTCGTPAYVAP 1006 +Y HSR V +R ++DFGL ++D A + T CGTP Y+AP Sbjct: 264 EYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGA----TMKTFCGTPEYLAP 319 Query: 1007 EVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELK 1186 EVL Y G D W GV+++ ++ G LPF+ + ++ I + + PR S E K Sbjct: 320 EVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAK 378 Query: 1187 DLLHKILDPDPSTRI 1231 LL +L DP R+ Sbjct: 379 SLLAGLLKKDPKQRL 393
>Q9Z2A0:PDPK1_MOUSE 3-phosphoinositide-dependent protein kinase 1 - Mus musculus (Mouse)| Length = 559 Score = 145 bits (365), Expect = 9e-34 Identities = 79/245 (32%), Positives = 130/245 (53%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 ++ GK LG+G+F+ V AR LAT + AIK++ K + K + + RE VM + HP Sbjct: 85 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 144 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++L+ K+YF L YAK GEL I K G +E R Y +++SA++Y H +G+ Sbjct: 145 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGI 204 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG + + + ++ GT YV+PE+L+ K Sbjct: 205 IHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS-AC 263 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 +D+W+ G I++ LVAG PF N ++++I K ++ P F + +DL+ K+L D Sbjct: 264 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEKFFPKARDLVEKLLVLD 323 Query: 1217 PSTRI 1231 + R+ Sbjct: 324 ATKRL 328
>O15530:PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 - Homo sapiens (Human)| Length = 556 Score = 145 bits (365), Expect = 9e-34 Identities = 79/245 (32%), Positives = 130/245 (53%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 ++ GK LG+G+F+ V AR LAT + AIK++ K + K + + RE VM + HP Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 141 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++L+ K+YF L YAK GEL I K G +E R Y +++SA++Y H +G+ Sbjct: 142 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGI 201 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG + + + ++ GT YV+PE+L+ K Sbjct: 202 IHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS-AC 260 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 +D+W+ G I++ LVAG PF N ++++I K ++ P F + +DL+ K+L D Sbjct: 261 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 320 Query: 1217 PSTRI 1231 + R+ Sbjct: 321 ATKRL 325
>O55173:PDPK1_RAT 3-phosphoinositide-dependent protein kinase 1 - Rattus norvegicus| (Rat) Length = 559 Score = 144 bits (364), Expect = 1e-33 Identities = 79/245 (32%), Positives = 130/245 (53%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 ++ GK LG+G+F+ V AR LAT + AIK++ K + K + + RE VM + HP Sbjct: 85 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 144 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++L+ K+YF L YAK GEL I K G +E R Y +++SA++Y H +G+ Sbjct: 145 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGI 204 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG + + + ++ GT YV+PE+L+ K Sbjct: 205 IHRDLKPENILLNEDMHIQITDFGTAKVLSPDSKQARANSFVGTAQYVSPELLTEKS-AC 263 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 +D+W+ G I++ LVAG PF N ++++I K ++ P F + +DL+ K+L D Sbjct: 264 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 323 Query: 1217 PSTRI 1231 + R+ Sbjct: 324 ATKRL 328
>Q9P7I2:KCC1_SCHPO Calcium/calmodulin-dependent protein kinase type I -| Schizosaccharomyces pombe (Fission yeast) Length = 335 Score = 144 bits (364), Expect = 1e-33 Identities = 92/283 (32%), Positives = 145/283 (51%), Gaps = 11/283 (3%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 +++ +L +Y +G+ LG GT+A V A ++ T + A K++NK + K + +K EI+ Sbjct: 22 DQKQLLPCKYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQ--DFVKNEIA 79 Query: 650 VMRLV--KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLI 823 +++ V +HPN+L L + T + +Y + E A GGELF++I +G E A Sbjct: 80 ILKRVSYEHPNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTT 139 Query: 824 SAIDYCHSRGVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPA 994 SA+ Y H G+ HR ++DFGLS + + Q +L T CGTP Sbjct: 140 SAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDS-QYYMLMTACGTPE 198 Query: 995 YVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADF----KCP 1162 Y+APEV R GY G D+W+ GVI + L++GY PF + +E+ I ++ C Sbjct: 199 YMAPEVFRRTGY-GKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCW 257 Query: 1163 RYFSAELKDLLHKILDPDPSTRIPISRIKKSAWY--RRPVEVN 1285 S KD + K L+ DPS R+ + K + +RP N Sbjct: 258 SGISETAKDFIKKCLENDPSKRLTAADALKHPFLSEKRPATSN 300
>Q63484:AKT3_RAT RAC-gamma serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 479 Score = 144 bits (364), Expect = 1e-33 Identities = 83/250 (33%), Positives = 130/250 (52%), Gaps = 2/250 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M ++ K LG+GTF KV R A+G+ A+K++ K+ + + E V++ + Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP + L TK ++ FV+EY GGELF + +E +ED R Y +++SA+DY HS Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGL--SALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 + +R ++DFGL + D A + T CGTP Y+APEVL Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAA----TMKTFCGTPEYLAPEVLED 320 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHK 1201 Y G D W GV+++ ++ G LPF+ + +++ I D K PR S++ K LL Sbjct: 321 NDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379 Query: 1202 ILDPDPSTRI 1231 +L DP+ R+ Sbjct: 380 LLIKDPNKRL 389
>Q9WUA6:AKT3_MOUSE RAC-gamma serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 479 Score = 144 bits (364), Expect = 1e-33 Identities = 83/250 (33%), Positives = 130/250 (52%), Gaps = 2/250 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M ++ K LG+GTF KV R A+G+ A+K++ K+ + + E V++ + Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP + L TK ++ FV+EY GGELF + +E +ED R Y +++SA+DY HS Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGL--SALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 + +R ++DFGL + D A + T CGTP Y+APEVL Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAA----TMKTFCGTPEYLAPEVLED 320 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHK 1201 Y G D W GV+++ ++ G LPF+ + +++ I D K PR S++ K LL Sbjct: 321 NDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379 Query: 1202 ILDPDPSTRI 1231 +L DP+ R+ Sbjct: 380 LLIKDPNKRL 389
>Q9Y243:AKT3_HUMAN RAC-gamma serine/threonine-protein kinase - Homo sapiens (Human)| Length = 479 Score = 144 bits (364), Expect = 1e-33 Identities = 83/250 (33%), Positives = 130/250 (52%), Gaps = 2/250 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 M ++ K LG+GTF KV R A+G+ A+K++ K+ + + E V++ + Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HP + L TK ++ FV+EY GGELF + +E +ED R Y +++SA+DY HS Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGL--SALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 + +R ++DFGL + D A + T CGTP Y+APEVL Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAA----TMKTFCGTPEYLAPEVLED 320 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHK 1201 Y G D W GV+++ ++ G LPF+ + +++ I D K PR S++ K LL Sbjct: 321 NDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSG 379 Query: 1202 ILDPDPSTRI 1231 +L DP+ R+ Sbjct: 380 LLIKDPNKRL 389
>Q9WTK7:STK11_MOUSE Serine/threonine-protein kinase 11 - Mus musculus (Mouse)| Length = 436 Score = 144 bits (363), Expect = 1e-33 Identities = 84/272 (30%), Positives = 145/272 (53%), Gaps = 6/272 (2%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIE-QIKREIS 649 +R L+G+Y +G LG+G++ KV + T A+K++ K K+ ++ E +K+EI Sbjct: 41 KRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQ 100 Query: 650 VMRLVKHPNVLQLFEVMAT--KSKIYFVLEYAKGG--ELFNKIVKEGKLNEDAARRYFHQ 817 ++R ++H NV+QL +V+ K K+Y V+EY G E+ + V E + A YF Q Sbjct: 101 LLRRLRHRNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDS-VPEKRFPVCQAHGYFRQ 159 Query: 818 LISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAY 997 LI ++Y HS+G+ H+ +SD G++ D T+ G+PA+ Sbjct: 160 LIDGLEYLHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAF 219 Query: 998 VAPEVLSRKG-YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFS 1174 PE+ + + G K D+WS+GV L+ + G PF N+ +++ I + DF P Sbjct: 220 QPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGRGDFTIPCDCG 279 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAWYRR 1270 L DLL +L+ +P+ R I +I++ +W+R+ Sbjct: 280 PPLSDLLRGMLEYEPAKRFSIRQIRQHSWFRK 311
>P42818:KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 - Arabidopsis thaliana| (Mouse-ear cress) Length = 465 Score = 144 bits (363), Expect = 1e-33 Identities = 87/286 (30%), Positives = 149/286 (52%), Gaps = 6/286 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E+ K +G+G F KVY R T + A+K++ KD + + E +K E ++ + HP Sbjct: 134 FEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPF 193 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++QL TK ++Y VL++ GG LF ++ +G ED AR Y +++SA+ + H +G+ Sbjct: 194 IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 253 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG LA ++ ++ CGT Y+APE++ KG+D Sbjct: 254 MHRDLKPENILMDTDGHVMLTDFG---LAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDK 310 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A AD WS G++L+ ++ G PF + ++ ++I K K P++ S E +L +L + Sbjct: 311 A-ADWWSVGILLYEMLTGKPPFLGSK-GKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKE 368 Query: 1217 PSTRI-----PISRIKKSAWYRRPVEVNAKKTEP-EATHTFSAEAA 1336 P R+ IK+ W++ +N KK E E +F E + Sbjct: 369 PERRLGSGLSGAEEIKQHKWFK---GINWKKLEAREVMPSFKPEVS 411
>P13186:KIN2_YEAST Serine/threonine-protein kinase KIN2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1147 Score = 144 bits (363), Expect = 1e-33 Identities = 82/298 (27%), Positives = 143/298 (47%), Gaps = 26/298 (8%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINK-------------DKVTKVGLIE 628 +G +E + +G G+ KV ++ T + IK++N+ + ++E Sbjct: 96 LGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILE 155 Query: 629 QIKR-------------EISVMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIV 769 + KR E S+ +++ HP++ +LFE+ + Y + EY GG+L + I+ Sbjct: 156 RQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYII 215 Query: 770 KEGKLNEDAARRYFHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADC 949 + G L E AR++ + SA+ Y H+ + HR + DFGLS + D Sbjct: 216 QHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDY 275 Query: 950 ARQDGLLHTTCGTPAYVAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMY 1129 +Q LHT CG+ + APE+L + Y G + D+WS G++L+VLV G +PF + N ++ Sbjct: 276 RKQ---LHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILH 332 Query: 1130 RRISKADFKCPRYFSAELKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEP 1303 +I K P + S E+ LL +++ DP R + + + W R + A P Sbjct: 333 EKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYDFKAPSYVP 390
>O61661:CHK1_DROME Serine/threonine-protein kinase grp - Drosophila melanogaster (Fruit| fly) Length = 512 Score = 144 bits (362), Expect = 2e-33 Identities = 93/306 (30%), Positives = 151/306 (49%), Gaps = 5/306 (1%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 + + + LG+G + +V N TG+AVA+KM++ K +++E+ + ++++ + Sbjct: 22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAA--NSVRKEVCIQKMLQDKH 79 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +L+ F + S Y LEYA GGELF++I + + + A+RYF QL+S ++Y H RG+ Sbjct: 80 ILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGI 139 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR +SDFG++ + C ++ LL CGT YVAPEVL +K Y Sbjct: 140 AHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHA 198 Query: 1037 AKADVWSSGVILFVLVAGYLPFHE--TNLIEM--YRRISKADFKCP-RYFSAELKDLLHK 1201 AD+WS GVIL ++AG LP+ + TN E +R + P LL K Sbjct: 199 QPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRK 258 Query: 1202 ILDPDPSTRIPISRIKKSAWYRRPVEVNAKKTEPEATHTFSAEAASSVSTGCSTSERNQG 1381 +L P TR+ + + W N + + + AA + + + +R Q Sbjct: 259 LLATSPGTRLTLEKTLDHKWCNMQFADNERSYD-----LVDSAAALEICSPKAKRQRLQS 313 Query: 1382 SLSLPN 1399 S L N Sbjct: 314 SAHLSN 319
>P53351:PLK2_MOUSE Serine/threonine-protein kinase PLK2 - Mus musculus (Mouse)| Length = 682 Score = 143 bits (361), Expect = 3e-33 Identities = 84/248 (33%), Positives = 127/248 (51%), Gaps = 3/248 (1%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 RY GK LG+G FAK Y +L + A K+I +V K E+I +EI + RL+ H Sbjct: 78 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHK 137 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 +V+Q + K IY +LEY + + + L E R Y Q++S + Y H + Sbjct: 138 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQE 197 Query: 854 VYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH---TTCGTPAYVAPEVLSRK 1024 + HR V DFGL+ AR + L H T CGTP Y++PEVL+++ Sbjct: 198 ILHRDLKLGNFFINEAMELKVGDFGLA-----ARLEPLEHRRRTICGTPNYLSPEVLNKQ 252 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 G+ G ++D+W+ G +++ ++ G PF TNL E YR I +A + P A K L+ + Sbjct: 253 GH-GCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASM 311 Query: 1205 LDPDPSTR 1228 L +P R Sbjct: 312 LSKNPEDR 319
>O61267:LOK_DROME Ovarian-specific serine/threonine-protein kinase Lok - Drosophila| melanogaster (Fruit fly) Length = 476 Score = 143 bits (361), Expect = 3e-33 Identities = 88/282 (31%), Positives = 145/282 (51%), Gaps = 16/282 (5%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKV------TKVGLIEQIKREISVMR 658 Y + ++LG G + V + T Q A+K++ K+ + T +++ E +M+ Sbjct: 174 YYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMK 233 Query: 659 LVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDY 838 + HP V+++ +++ +Y VLE+ +GG+L N+I+ L+ED ++ YF+Q+ A+ Y Sbjct: 234 NLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKY 293 Query: 839 CHSRGVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 H RG+ HR VSDFGLS ++D ++ T CGTP YVAPE Sbjct: 294 LHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKF---VQKDSVMRTLCGTPLYVAPE 350 Query: 1010 VLSRKGYDG--AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCP----RYF 1171 VL G + K D+WS GV+LF ++G LPF + ++I K F + Sbjct: 351 VLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSV 410 Query: 1172 SAELKDLLHKILDPDPSTRIPISRIKKSAWYR-RPVEVNAKK 1294 S K L++++L DP R I + +S+W R P+ AK+ Sbjct: 411 SQRAKLLINQMLIVDPERRPSIDDVLQSSWLRDAPMLQKAKR 452
>P47197:AKT2_RAT RAC-beta serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 481 Score = 143 bits (361), Expect = 3e-33 Identities = 82/253 (32%), Positives = 127/253 (50%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 R + M ++ K LG+GTF KV R ATG+ A+K++ K+ + + E V Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ +HP + L T ++ FV+EYA GG+LF + +E ED AR Y +++SA+ Sbjct: 204 LQNTRHPFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSAL 263 Query: 833 DYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 +Y HS V +R ++DFGLS + + T CGTP Y+APEV Sbjct: 264 EYLHSTDVVYRDIKLENLMLDKDGHIKITDFGLS--KEGISDGATMKTFCGTPEYLAPEV 321 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDL 1192 L Y G D W GV+++ ++ G LPF+ + ++ I + + PR E K L Sbjct: 322 LEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSL 380 Query: 1193 LHKILDPDPSTRI 1231 L +L DP R+ Sbjct: 381 LAGLLKKDPKQRL 393
>Q9R012:PLK2_RAT Serine/threonine-protein kinase PLK2 - Rattus norvegicus (Rat)| Length = 682 Score = 142 bits (359), Expect = 4e-33 Identities = 83/248 (33%), Positives = 127/248 (51%), Gaps = 3/248 (1%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 RY GK LG+G FAK Y +L + A K+I +V K E+I +EI + R++ H Sbjct: 78 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHK 137 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 +V+Q + K IY +LEY + + + L E R Y Q++S + Y H + Sbjct: 138 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQE 197 Query: 854 VYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH---TTCGTPAYVAPEVLSRK 1024 + HR V DFGL+ AR + L H T CGTP Y++PEVL+++ Sbjct: 198 ILHRDLKLGNFFINEAMELKVGDFGLA-----ARLEPLEHRRRTICGTPNYLSPEVLNKQ 252 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 G+ G ++D+W+ G +++ ++ G PF TNL E YR I +A + P A K L+ + Sbjct: 253 GH-GCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASM 311 Query: 1205 LDPDPSTR 1228 L +P R Sbjct: 312 LSKNPEDR 319
>Q5R4L1:PLK2_PONPY Serine/threonine-protein kinase PLK2 - Pongo pygmaeus (Orangutan)| Length = 685 Score = 142 bits (359), Expect = 4e-33 Identities = 83/248 (33%), Positives = 127/248 (51%), Gaps = 3/248 (1%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 RY GK LG+G FAK Y +L + A K+I +V K E+I +EI + R++ H Sbjct: 81 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHK 140 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 +V+Q + K IY +LEY + + + L E R Y Q++S + Y H + Sbjct: 141 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQE 200 Query: 854 VYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH---TTCGTPAYVAPEVLSRK 1024 + HR V DFGL+ AR + L H T CGTP Y++PEVL+++ Sbjct: 201 ILHRDLKLGNFFINEAMELKVGDFGLA-----ARLEPLEHRRRTICGTPNYLSPEVLNKQ 255 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 G+ G ++D+W+ G +++ ++ G PF TNL E YR I +A + P A K L+ + Sbjct: 256 GH-GCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASM 314 Query: 1205 LDPDPSTR 1228 L +P R Sbjct: 315 LSKNPEDR 322
>Q9NYY3:PLK2_HUMAN Serine/threonine-protein kinase PLK2 - Homo sapiens (Human)| Length = 685 Score = 142 bits (359), Expect = 4e-33 Identities = 83/248 (33%), Positives = 127/248 (51%), Gaps = 3/248 (1%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHP 673 RY GK LG+G FAK Y +L + A K+I +V K E+I +EI + R++ H Sbjct: 81 RYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHK 140 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 +V+Q + K IY +LEY + + + L E R Y Q++S + Y H + Sbjct: 141 HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQE 200 Query: 854 VYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLH---TTCGTPAYVAPEVLSRK 1024 + HR V DFGL+ AR + L H T CGTP Y++PEVL+++ Sbjct: 201 ILHRDLKLGNFFINEAMELKVGDFGLA-----ARLEPLEHRRRTICGTPNYLSPEVLNKQ 255 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 G+ G ++D+W+ G +++ ++ G PF TNL E YR I +A + P A K L+ + Sbjct: 256 GH-GCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASM 314 Query: 1205 LDPDPSTR 1228 L +P R Sbjct: 315 LSKNPEDR 322
>Q9N2L7:PLK2_CAEEL Serine/threonine-protein kinase plk-2 - Caenorhabditis elegans| Length = 632 Score = 142 bits (358), Expect = 6e-33 Identities = 84/253 (33%), Positives = 130/253 (51%) Frame = +2 Query: 470 ERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREIS 649 ER+T RYE GK LG+G FA Y RN +TG+ A K++ K + K +++ +E+ Sbjct: 31 ERKT----RYEKGKFLGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQ 86 Query: 650 VMRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISA 829 + R ++H NV++L+ KS +Y LE L + + E AR + +Q++ Sbjct: 87 IHRNLQHRNVVKLYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTYQIVEG 146 Query: 830 IDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 + Y H+ + HR + DFGL+ D D T CGTP Y+APE Sbjct: 147 VLYLHNLKIVHRDLKLGNLFLNDELQVKIGDFGLATTCD---NDERKKTLCGTPNYIAPE 203 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 VL++ G+ + D+W+ G IL++L+ G+ PF +L E Y RI ++ P SA Sbjct: 204 VLNKIGH-SFEVDLWAIGCILYILLFGHPPFESKSLEETYSRIKNNNYVIPTSASAAASQ 262 Query: 1190 LLHKILDPDPSTR 1228 L+ +LDP PS R Sbjct: 263 LIRVLLDPVPSRR 275
>P53682:CDPK1_ORYSJ Calcium-dependent protein kinase, isoform 1 - Oryza sativa subsp.| japonica (Rice) Length = 534 Score = 142 bits (358), Expect = 6e-33 Identities = 89/263 (33%), Positives = 131/263 (49%), Gaps = 8/263 (3%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMR-LVKHP 673 Y +G++LGQG F K Y ++TG A K I K + V IE ++REI +M L Sbjct: 73 YTLGRELGQGQFGKTYLCTEISTGCQYACKTILKSNLRCVSDIEDVRREIQIMHHLSGQK 132 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 N++ + + + ++ V+E GGELF+KI K G +E A ++ I+ CHS G Sbjct: 133 NIVTIKDTYEDEQAVHIVMELCAGGELFSKIQKRGHYSERKAAELIKIIVGIIETCHSHG 192 Query: 854 VYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 V HR DFGLS R + G+P Y+APEVL ++ Sbjct: 193 VMHRDLKPENFLLLDADDEFSVKAIDFGLSVF---FRPGQVFREVVGSPYYIAPEVLEKR 249 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRI--SKADFKCPRY--FSAELKDL 1192 G +AD+W++GVIL+VL+ G PF +Y ++ + DFK R+ S KDL Sbjct: 250 --YGPEADIWTAGVILYVLLTGVPPFWADTQSGIYEKVLDGRIDFKSNRWPRISDSAKDL 307 Query: 1193 LHKILDPDPSTRIPISRIKKSAW 1261 + K+L P PS R+ + K W Sbjct: 308 IKKMLCPYPSERLKAHEVLKHPW 330
>P31748:AKT_MLVAT AKT kinase-transforming protein - AKT8 murine leukemia virus| Length = 501 Score = 142 bits (358), Expect = 6e-33 Identities = 82/254 (32%), Positives = 131/254 (51%), Gaps = 1/254 (0%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + + M +E K LG+GTF KV + ATG+ A+K++ K+ + + E V Sbjct: 163 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 222 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ +HP + L T ++ FV+EYA GGELF + +E +ED AR Y +++SA+ Sbjct: 223 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 282 Query: 833 DYCHS-RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 DY HS + V +R ++DFGL + + + T CGTP Y+APE Sbjct: 283 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGL--CKEGIKDGATMKTFCGTPEYLAPE 340 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 VL Y G D W GV+++ ++ G LPF+ + +++ I + + PR E K Sbjct: 341 VLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKS 399 Query: 1190 LLHKILDPDPSTRI 1231 LL +L DP+ R+ Sbjct: 400 LLSGLLKKDPTQRL 413
>P47196:AKT1_RAT RAC-alpha serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 480 Score = 142 bits (358), Expect = 6e-33 Identities = 82/254 (32%), Positives = 131/254 (51%), Gaps = 1/254 (0%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + + M +E K LG+GTF KV + ATG+ A+K++ K+ + + E V Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ +HP + L T ++ FV+EYA GGELF + +E +ED AR Y +++SA+ Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 261 Query: 833 DYCHS-RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 DY HS + V +R ++DFGL + + + T CGTP Y+APE Sbjct: 262 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGL--CKEGIKDGATMKTFCGTPEYLAPE 319 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 VL Y G D W GV+++ ++ G LPF+ + +++ I + + PR E K Sbjct: 320 VLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKS 378 Query: 1190 LLHKILDPDPSTRI 1231 LL +L DP+ R+ Sbjct: 379 LLSGLLKKDPTQRL 392
>P31749:AKT1_HUMAN RAC-alpha serine/threonine-protein kinase - Homo sapiens (Human)| Length = 480 Score = 142 bits (357), Expect = 7e-33 Identities = 82/254 (32%), Positives = 130/254 (51%), Gaps = 1/254 (0%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + + M +E K LG+GTF KV + ATG+ A+K++ K+ + + E V Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ +HP + L T ++ FV+EYA GGELF + +E +ED AR Y +++SA+ Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 261 Query: 833 DYCHS-RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 DY HS + V +R ++DFGL + + + T CGTP Y+APE Sbjct: 262 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGL--CKEGIKDGATMKTFCGTPEYLAPE 319 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 VL Y G D W GV+++ ++ G LPF+ + +++ I + + PR E K Sbjct: 320 VLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKS 378 Query: 1190 LLHKILDPDPSTRI 1231 LL +L DP R+ Sbjct: 379 LLSGLLKKDPKQRL 392
>Q01314:AKT1_BOVIN RAC-alpha serine/threonine-protein kinase - Bos taurus (Bovine)| Length = 480 Score = 142 bits (357), Expect = 7e-33 Identities = 83/254 (32%), Positives = 131/254 (51%), Gaps = 1/254 (0%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + + M +E K LG+GTF KV + ATG+ A+K++ K+ + + E V Sbjct: 142 KHRVTMNDFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ +HP + L T ++ FV+EYA GGELF + +E +ED AR Y +++SA+ Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 261 Query: 833 DYCHS-RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 DY HS + V +R ++DFGL + + + T CGTP Y+APE Sbjct: 262 DYLHSEKEVVYRDLKLENLMLDKDGHIKITDFGL--CKEGIKDGATMKTFCGTPEYLAPE 319 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 VL Y G D W GV+++ ++ G LPF+ + +++ I + + PR S E K Sbjct: 320 VLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLSPEAKS 378 Query: 1190 LLHKILDPDPSTRI 1231 LL +L DP R+ Sbjct: 379 LLSGLLKKDPKQRL 392
>Q91604:STK11_XENLA Serine/threonine-protein kinase 11 - Xenopus laevis (African clawed| frog) Length = 432 Score = 141 bits (356), Expect = 1e-32 Identities = 83/272 (30%), Positives = 144/272 (52%), Gaps = 6/272 (2%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIE-QIKREIS 649 +R L+G+Y +G LG+G++ KV + T A+K++ K K+ ++ E +K+EI Sbjct: 44 KRAKLVGKYLMGDLLGEGSYGKVKEMLDSDTLCRRAVKILKKKKLRRIPNGEANVKKEIQ 103 Query: 650 VMRLVKHPNVLQLFEVMAT--KSKIYFVLEYAKGG--ELFNKIVKEGKLNEDAARRYFHQ 817 ++R ++H NV+QL +V+ K K+Y V+EY G E+ + V++ A YF Q Sbjct: 104 LLRRLRHRNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDS-VQDKHFPVFQAHGYFCQ 162 Query: 818 LISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAY 997 LI ++Y HS+G+ H+ +SD G++ + T+ G+PA+ Sbjct: 163 LIDGLEYLHSQGIVHKDIKPGNLLLTTDGTLKISDLGVAEALHPFAEGDTCRTSQGSPAF 222 Query: 998 VAPEVLSRKG-YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFS 1174 PE+ + + G K D+WS+GV L+ + G PF N+ +++ I K D+ P Sbjct: 223 QPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGDYSIPEECG 282 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAWYRR 1270 L DLL +L+ DP+ R I +I++ W+R+ Sbjct: 283 PLLSDLLRGMLEYDPAKRFSIQQIRQHNWFRK 314
>Q15831:STK11_HUMAN Serine/threonine-protein kinase 11 - Homo sapiens (Human)| Length = 433 Score = 141 bits (356), Expect = 1e-32 Identities = 83/272 (30%), Positives = 144/272 (52%), Gaps = 6/272 (2%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIE-QIKREIS 649 +R L+G+Y +G LG+G++ KV + T A+K++ K K+ ++ E +K+EI Sbjct: 41 KRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQ 100 Query: 650 VMRLVKHPNVLQLFEVMAT--KSKIYFVLEYAKGG--ELFNKIVKEGKLNEDAARRYFHQ 817 ++R ++H NV+QL +V+ K K+Y V+EY G E+ + V E + A YF Q Sbjct: 101 LLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDS-VPEKRFPVCQAHGYFCQ 159 Query: 818 LISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAY 997 LI ++Y HS+G+ H+ +SD G++ D T+ G+PA+ Sbjct: 160 LIDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAF 219 Query: 998 VAPEVLSRKG-YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFS 1174 PE+ + + G K D+WS+GV L+ + G PF N+ +++ I K + P Sbjct: 220 QPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCG 279 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAWYRR 1270 L DLL +L+ +P+ R I +I++ +W+R+ Sbjct: 280 PPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRK 311
>P31750:AKT1_MOUSE RAC-alpha serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 480 Score = 141 bits (355), Expect = 1e-32 Identities = 82/254 (32%), Positives = 130/254 (51%), Gaps = 1/254 (0%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + + M +E K LG+GTF KV + ATG+ A+K++ K+ + + E V Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ +HP + L T ++ FV+EYA GGELF + +E +ED AR Y +++SA+ Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 261 Query: 833 DYCHS-RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 DY HS + V +R ++DFGL + + + T CGTP Y+APE Sbjct: 262 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGL--CKEGIKDGATMKTFCGTPEYLAPE 319 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 VL Y G D W GV+++ ++ G LPF+ + +++ I + PR E K Sbjct: 320 VLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIAFPRTLGPEAKS 378 Query: 1190 LLHKILDPDPSTRI 1231 LL +L DP+ R+ Sbjct: 379 LLSGLLKKDPTQRL 392
>P28582:CDPK_DAUCA Calcium-dependent protein kinase - Daucus carota (Carrot)| Length = 532 Score = 140 bits (354), Expect = 2e-32 Identities = 91/277 (32%), Positives = 143/277 (51%), Gaps = 8/277 (2%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMR-L 661 + G+Y +GK+LG+G F VY ++GQ A K I K K+ E IKREI +++ L Sbjct: 77 IRGKYTLGKELGRGQFGCVYQCTENSSGQLYACKSILKRKLVSKNDKEDIKREIQILQHL 136 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 PN+++ V + ++ V+E GGELF++I+ +G +E AA Q+++ + C Sbjct: 137 SGQPNIVEFKGVFEDRQSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVVHVC 196 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXV---SDFGLSALADCARQDGLLHTTCGTPAYVAPEV 1012 H GV HR + +DFGLS + + + G+ YVAPEV Sbjct: 197 HFMGVMHRDLKPENFLLSSKDKDAMLKATDFGLSVFIE---EGKVYRNIVGSAYYVAPEV 253 Query: 1013 LSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAE 1180 L R+ Y G + D+WS+GVIL++L++G PF N ++ I + DF+ + S Sbjct: 254 L-RRSY-GKEIDIWSAGVILYILLSGVPPFWAENEKGIFDAILEGVIDFESEPWPSVSNS 311 Query: 1181 LKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEVNAK 1291 KDL+ K+L DP RI +++ W R E + K Sbjct: 312 AKDLVRKMLTQDPRRRITSAQVLDHPWMREGGEASDK 348
>Q98TY9:AKT1_XENLA RAC-alpha serine/threonine-protein kinase - Xenopus laevis (African| clawed frog) Length = 481 Score = 140 bits (354), Expect = 2e-32 Identities = 82/254 (32%), Positives = 130/254 (51%), Gaps = 1/254 (0%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 + + M +E K LG+GTF KV + ATG+ A+K++ K+ + + E V Sbjct: 143 KHKVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 202 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 ++ +HP + L T ++ FV+EYA GGELF + +E +ED AR Y +++SA+ Sbjct: 203 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERIFSEDRARFYGAEIVSAL 262 Query: 833 DYCHS-RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 DY HS + V +R ++DFGL + + + T CGTP Y+APE Sbjct: 263 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGL--CKEGIKDGATMKTFCGTPEYLAPE 320 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKD 1189 VL Y G D W GV+++ ++ G LPF+ + +++ I + + PR E K Sbjct: 321 VLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLLPEAKS 379 Query: 1190 LLHKILDPDPSTRI 1231 LL +L DP R+ Sbjct: 380 LLSGLLKKDPKQRL 393
>Q6SA08:TSSK4_HUMAN Testis-specific serine/threonine-protein kinase 4 - Homo sapiens| (Human) Length = 328 Score = 140 bits (353), Expect = 2e-32 Identities = 85/269 (31%), Positives = 135/269 (50%), Gaps = 14/269 (5%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YE+GK +G G++ VY A VA+K+I+K K + L + + REI VM++++H Sbjct: 25 YEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKY 84 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ + + + S++Y +LE A+GG++ I + G +E A ++F QL I Y HS+ + Sbjct: 85 LINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSI 144 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDG-------------LLHTTCGTPAY 997 HR +SDFG + + + G L T CG+ AY Sbjct: 145 VHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAY 204 Query: 998 VAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISK-ADFKCPRYFS 1174 PE+L Y+ +D WS GVIL+ LV +LPF +TNL ++ R K F S Sbjct: 205 ACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTIS 264 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAW 1261 E K+L+ ++L + R I I K +W Sbjct: 265 QECKNLILQML-RQATKRATILDIIKDSW 292
>P08414:KCC4_MOUSE Calcium/calmodulin-dependent protein kinase type IV - Mus musculus| (Mouse) Length = 469 Score = 139 bits (351), Expect = 4e-32 Identities = 85/267 (31%), Positives = 138/267 (51%), Gaps = 12/267 (4%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 +E+ +LG+G + VY + T + A+K++ K K+ ++ EI V+ + HPN Sbjct: 42 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-----VRTEIGVLLRLSHPN 96 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L E+ T ++I VLE GGELF++IV++G +E AR Q++ A+ Y H G+ Sbjct: 97 IIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAVAYLHENGI 156 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGLS + + L+ T CGTP Y APE+L Sbjct: 157 VHRDLKPENLLYATPAPDAPLKIADFGLSKIVE---HQVLMKTVCGTPGYCAPEILRGCA 213 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIE-MYRRISKADFKCPRYF--------SAE 1180 Y G + D+WS G+I ++L+ G+ PF++ + M+RRI C YF S Sbjct: 214 Y-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRI----LNCEYYFISPWWDEVSLN 268 Query: 1181 LKDLLHKILDPDPSTRIPISRIKKSAW 1261 KDL+ K++ DP R+ + + W Sbjct: 269 AKDLVKKLIVLDPKKRLTTFQALQHPW 295
>Q6PFQ0:KS6A6_DANRE Ribosomal protein S6 kinase alpha-6 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 740 Score = 139 bits (350), Expect = 5e-32 Identities = 91/298 (30%), Positives = 152/298 (51%), Gaps = 19/298 (6%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLA---TGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 ++E+ K LGQG+F KV+ R L GQ A+K++ K + KV + K E ++ V Sbjct: 66 QFELLKVLGQGSFGKVFLVRKLMGPDAGQLYAMKVLKKASL-KVRDRVRTKMERDILVEV 124 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP +++L T+ K+Y +L++ +GG++F ++ KE E+ + Y +L A+D+ H Sbjct: 125 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVMFTEEDVKFYLAELALALDHLH 184 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 + G+ +R ++DFGLS + QD ++ CGT Y+APEV++R+ Sbjct: 185 NLGIVYRDLKPENILLDEAGHIKLTDFGLS--KESVDQDKKAYSFCGTVEYMAPEVVNRR 242 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 G+ AD WS GV++F ++ G LPF + E I KA P++ S E + LL + Sbjct: 243 GHT-QSADWWSLGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSLEAQGLLRML 301 Query: 1205 LDPDPSTRI-----PISRIKKSAW---------YRRPVEVNAKKT--EPEATHTFSAE 1330 +PS R+ + IK+ + YRR ++ K +P+ T F E Sbjct: 302 FKRNPSNRLGAGPDGVEEIKRHTFFSTIDWNKLYRRELQPPFKPASGKPDDTFCFDPE 359 Score = 122 bits (305), Expect = 8e-27 Identities = 91/296 (30%), Positives = 135/296 (45%), Gaps = 12/296 (4%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YE+ + +G G+++ + T A+K+I+K K IE + MR +HPN Sbjct: 420 YELKEDIGVGSYSICKRCIHRVTAMEFAVKIIDKSKRDPSEEIEIL------MRYGQHPN 473 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L +V +Y V E KGGEL +KI+++ +E A + + +DY H +GV Sbjct: 474 IITLKDVYDEGRFVYLVTELMKGGELLDKILRQKFFSEREASAVLYTITKTVDYLHCQGV 533 Query: 857 YHR----XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 HR + DFG + +GLL T C T +VAPEVL R+ Sbjct: 534 VHRDLKPSNILYMDDSGNPDSIRICDFGFA--KQLRGDNGLLLTPCYTANFVAPEVLMRQ 591 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPF---HETNLIEMYRRISKADFKCP----RYFSAEL 1183 GYD A D+WS GV+L+ ++AGY PF E+ RI F S Sbjct: 592 GYDAA-CDIWSLGVLLYTMLAGYTPFANGPNDTPEEILLRIGSGKFSLSGGNWDSVSDSS 650 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAWYR-RPVEVNAKKTEPEATHTFSAEAASSVS 1348 KDLL +L DP R ++ K +W R + + T EA H A++ S Sbjct: 651 KDLLSHMLHVDPHHRYTAEQVLKHSWIACRDQNPHFQLTRHEAPHLVKGAMAATYS 706
>Q683C9:AUR2_ARATH Serine/threonine-protein kinase Aurora-2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 282 Score = 139 bits (350), Expect = 5e-32 Identities = 78/257 (30%), Positives = 133/257 (51%), Gaps = 2/257 (0%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 ++IGK LG+G F VY AR + VA+K++ K ++ + + Q++RE+ + ++HPN Sbjct: 19 FDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQSQVEHQLRREVEIQSHLRHPN 78 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +L+L+ + ++Y +LEYA GEL+ ++ K +E A Y L A+ YCH + V Sbjct: 79 ILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVASLARALIYCHGKHV 138 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR ++DFG S R+ T CGT Y+ PE++ +D Sbjct: 139 IHRDIKPENLLIGAQGELKIADFGWSVHTFNRRR-----TMCGTLDYLPPEMVESVEHD- 192 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCP--RYFSAELKDLLHKILD 1210 A D+WS G++ + + G PF E Y+RI + D K P S+ KDL+ ++L Sbjct: 193 ASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSSSAKDLISQMLV 252 Query: 1211 PDPSTRIPISRIKKSAW 1261 + + R+ + ++ + W Sbjct: 253 KESTQRLALHKLLEHPW 269
>Q8INB9:AKT1_DROME RAC serine/threonine-protein kinase - Drosophila melanogaster (Fruit| fly) Length = 611 Score = 139 bits (349), Expect = 6e-32 Identities = 81/252 (32%), Positives = 126/252 (50%) Frame = +2 Query: 476 RTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVM 655 + + + +E K LG+GTF KV R AT + AIK++ K+ + + + E V+ Sbjct: 259 KKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVL 318 Query: 656 RLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAID 835 + HP ++ L T ++ FV++Y GGELF + E ED R Y ++ISA+ Sbjct: 319 KSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALG 378 Query: 836 YCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVL 1015 Y HS+G+ +R V+DFGL + T CGTP Y+APEVL Sbjct: 379 YLHSQGIIYRDLKLENLLLDKDGHIKVADFGL--CKEDITYGRTTKTFCGTPEYLAPEVL 436 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLL 1195 Y G D W +GV+++ ++ G LPF+ + ++ I + K PR + E K+LL Sbjct: 437 DDNDY-GQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLL 495 Query: 1196 HKILDPDPSTRI 1231 +L DP R+ Sbjct: 496 AGLLAKDPKKRL 507
>Q9D411:TSSK4_MOUSE Testis-specific serine/threonine-protein kinase 4 - Mus musculus| (Mouse) Length = 328 Score = 138 bits (348), Expect = 8e-32 Identities = 84/269 (31%), Positives = 137/269 (50%), Gaps = 14/269 (5%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YE+GK +G G++ VY A VA+K+I+K K ++ L + + REI VM++++H Sbjct: 25 YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKY 84 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ ++ + T S++Y +LE A+GG++ I + G E A ++F Q+ I Y HS+G+ Sbjct: 85 LINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFSQMALGIAYLHSKGI 144 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCA----------RQDGLLH---TTCGTPAY 997 HR +SDFG + + + + + L H T CG+ AY Sbjct: 145 VHRDLKLENLLLDKRENVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAY 204 Query: 998 VAPEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISK-ADFKCPRYFS 1174 PE+L Y+ +D WS GVIL+ LV LPF +TNL ++ R K F S Sbjct: 205 ACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLRETQKEVTFPANLTIS 264 Query: 1175 AELKDLLHKILDPDPSTRIPISRIKKSAW 1261 E K+L+ ++L + R I + + W Sbjct: 265 QECKNLILQLL-RQSTKRATILDVLRDPW 292
>Q21734:KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-1 - Caenorhabditis elegans| Length = 784 Score = 138 bits (348), Expect = 8e-32 Identities = 88/311 (28%), Positives = 161/311 (51%), Gaps = 10/311 (3%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLA---TGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 ++E+ K LGQG+F KV+ R + +G A+K++ K + KV ++ K E +++ + Sbjct: 103 QFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATL-KVRDRQRTKLERNILAHI 161 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP +++L T+ K+Y +L++ +GG+LF ++ KE ED + Y +L A+++ H Sbjct: 162 SHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLH 221 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 S G+ +R V+DFGLS + + ++ CGT Y+APEV++R+ Sbjct: 222 SLGIVYRDLKPENILLDADGHIKVTDFGLS--KEAIDSEKKTYSFCGTVEYMAPEVINRR 279 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 G+ A AD WS GV++F ++ G+LPF + + +I KA P + + E + LL + Sbjct: 280 GHSMA-ADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRAL 338 Query: 1205 LDPDPSTRI-----PISRIKKSAWYRRP--VEVNAKKTEPEATHTFSAEAASSVSTGCST 1363 + R+ + IK+ A++ + V++ K+ +P S ++S T Sbjct: 339 FKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFT 398 Query: 1364 SERNQGSLSLP 1396 + S +LP Sbjct: 399 KRTPKDSPALP 409 Score = 108 bits (269), Expect = 1e-22 Identities = 79/267 (29%), Positives = 130/267 (48%), Gaps = 12/267 (4%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YEI +++G G + V+ + AT + A+K++ K + + + ++R H Sbjct: 454 YEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKK------AVFDATEEVDILLRHSHHQF 507 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKL-NEDAARRYFHQLISAIDYCHSRG 853 V++LF+V ++ IY + E +GGEL +K+V + L +E L++A+ Y HS+ Sbjct: 508 VVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQ 567 Query: 854 VYHRXXXXXXXXXXXXXXXXVS----DFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 V HR S DFG + ++G+L T C T +VAPEVL + Sbjct: 568 VAHRDLTAANILFALKDGDPSSLRIVDFGFA--KQSRAENGMLMTPCYTAQFVAPEVLRK 625 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPF---HETNLIEMYRRI--SKADFKCPRY--FSAE 1180 +GYD DVWS GV+L ++ G PF ++ +R+ K P + S E Sbjct: 626 QGYD-RSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDE 684 Query: 1181 LKDLLHKILDPDPSTRIPISRIKKSAW 1261 KDL+ K+LD DP+ R+ + + W Sbjct: 685 AKDLVRKMLDVDPNRRVTAKQALQHKW 711
>Q16566:KCC4_HUMAN Calcium/calmodulin-dependent protein kinase type IV - Homo sapiens| (Human) Length = 473 Score = 138 bits (348), Expect = 8e-32 Identities = 86/274 (31%), Positives = 139/274 (50%), Gaps = 12/274 (4%) Frame = +2 Query: 476 RTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVM 655 R L +E+ +LG+G + VY + T + A+K++ K K+ ++ EI V+ Sbjct: 39 RDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-----VRTEIGVL 93 Query: 656 RLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAID 835 + HPN+++L E+ T ++I VLE GGELF++IV++G +E A Q++ A+ Sbjct: 94 LRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVA 153 Query: 836 YCHSRGVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAP 1006 Y H G+ HR ++DFGLS + + L+ T CGTP Y AP Sbjct: 154 YLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVE---HQVLMKTVCGTPGYCAP 210 Query: 1007 EVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIE-MYRRISKADFKCPRYF---- 1171 E+L Y G + D+WS G+I ++L+ G+ PF++ + M+RRI C YF Sbjct: 211 EILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRI----LNCEYYFISPW 265 Query: 1172 ----SAELKDLLHKILDPDPSTRIPISRIKKSAW 1261 S KDL+ K++ DP R+ + + W Sbjct: 266 WDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPW 299
>Q9H4B4:PLK3_HUMAN Serine/threonine-protein kinase PLK3 - Homo sapiens (Human)| Length = 646 Score = 138 bits (347), Expect = 1e-31 Identities = 87/258 (33%), Positives = 126/258 (48%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y G+ LG+G FA+ Y A + TG A A+K+I + +V K E+I EI + R ++H + Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH 121 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++ IY LE L + L E R Y Q++S + Y H RG+ Sbjct: 122 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 181 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 HR V DFGL+A + Q T CGTP YVAPEVL R+G+ G Sbjct: 182 LHRDLKLGNFFITENMELKVGDFGLAARLEPPEQ--RKKTICGTPNYVAPEVLLRQGH-G 238 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 +ADVWS G +++ L+ G PF +L E YR I + + P S + LL IL Sbjct: 239 PEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRAS 298 Query: 1217 PSTRIPISRIKKSAWYRR 1270 P R I +I + ++ + Sbjct: 299 PRDRPSIDQILRHDFFTK 316
>P13234:KCC4_RAT Calcium/calmodulin-dependent protein kinase type IV - Rattus| norvegicus (Rat) Length = 474 Score = 138 bits (347), Expect = 1e-31 Identities = 86/275 (31%), Positives = 140/275 (50%), Gaps = 12/275 (4%) Frame = +2 Query: 473 RRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISV 652 +R L +E+ +LG+G + VY + T + A+K++ K K+ ++ EI V Sbjct: 34 KRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-----VRTEIGV 88 Query: 653 MRLVKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAI 832 + + HPN+++L E+ T ++I VLE GGELF++IV++G +E A Q++ A+ Sbjct: 89 LLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAV 148 Query: 833 DYCHSRGVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVA 1003 Y H G+ HR ++DFGLS + + L+ T CGTP Y A Sbjct: 149 AYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVE---HQVLMKTVCGTPGYCA 205 Query: 1004 PEVLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIE-MYRRISKADFKCPRYF--- 1171 PE+L Y G + D+WS G+I ++L+ G+ PF++ + M+RRI C YF Sbjct: 206 PEILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRI----LNCEYYFISP 260 Query: 1172 -----SAELKDLLHKILDPDPSTRIPISRIKKSAW 1261 S KDL+ K++ DP R+ + + W Sbjct: 261 WWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPW 295
>Q5ZKI0:KCC2D_CHICK Calcium/calmodulin-dependent protein kinase type II delta chain -| Gallus gallus (Chicken) Length = 479 Score = 138 bits (347), Expect = 1e-31 Identities = 83/262 (31%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + TGQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKITTGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 72 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y V + GGELF IV +E A Q++ ++++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ +Q GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGEQQ--AWFGFAGTPGYLSPEVLRKDP 190 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +P+ RI S K W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>O15865:CDPK2_PLAFK Calcium-dependent protein kinase 2 - Plasmodium falciparum (isolate| K1 / Thailand) Length = 513 Score = 138 bits (347), Expect = 1e-31 Identities = 89/266 (33%), Positives = 131/266 (49%), Gaps = 7/266 (2%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L +Y I ++LGQGT+ VY + T Q AIK KD++ + Q EI +M+ + Sbjct: 68 LEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQ---EIEIMKKL 124 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HPN+++L+E + IY ++E G ELF+ I++ G E A Q+ SAI Y H Sbjct: 125 DHPNIVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLH 184 Query: 845 SRGVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVL 1015 S + HR + DFGLS T GTP YVAP+VL Sbjct: 185 SLNIVHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGE---FTTTKAGTPYYVAPQVL 241 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPR----YFSAEL 1183 K YD K D+WSSGVI++ L+ GY PF+ E+ +++ K +F S++ Sbjct: 242 DGK-YD-KKCDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDA 299 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAW 1261 K+L+ K+L +P+ R I W Sbjct: 300 KNLITKLLTYNPNERCTIEEALNHPW 325
>Q8ICR0:CDPK2_PLAF7 Calcium-dependent protein kinase 2 - Plasmodium falciparum (isolate| 3D7) Length = 509 Score = 138 bits (347), Expect = 1e-31 Identities = 89/266 (33%), Positives = 131/266 (49%), Gaps = 7/266 (2%) Frame = +2 Query: 485 LMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 L +Y I ++LGQGT+ VY + T Q AIK KD++ + Q EI +M+ + Sbjct: 68 LEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQ---EIEIMKKL 124 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HPN+++L+E + IY ++E G ELF+ I++ G E A Q+ SAI Y H Sbjct: 125 DHPNIVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLH 184 Query: 845 SRGVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVL 1015 S + HR + DFGLS T GTP YVAP+VL Sbjct: 185 SLNIVHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGE---FTTTKAGTPYYVAPQVL 241 Query: 1016 SRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPR----YFSAEL 1183 K YD K D+WSSGVI++ L+ GY PF+ E+ +++ K +F S++ Sbjct: 242 DGK-YD-KKCDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDA 299 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAW 1261 K+L+ K+L +P+ R I W Sbjct: 300 KNLITKLLTYNPNERCTIEEALNHPW 325
>Q12152:YP150_YEAST Putative serine/threonine-protein kinase YPL150W - Saccharomyces| cerevisiae (Baker's yeast) Length = 901 Score = 137 bits (345), Expect = 2e-31 Identities = 80/254 (31%), Positives = 134/254 (52%), Gaps = 1/254 (0%) Frame = +2 Query: 488 MGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVK 667 +G Y+I KQ+G+G+F KVY A + T + V +K +K+ I RE+ R Sbjct: 38 VGNYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKND-------PNIVREVFYHRQFD 90 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 P + +L+EV+ T+SK++ LEY G EL++ ++ +++ F Q+ A+ Y HS Sbjct: 91 FPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHS 150 Query: 848 RGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFG + +C + L T CGT Y+APE++ R+ Sbjct: 151 MHCVHRDLKLENILLDKNGNAKLTDFGFTR--ECMTKT-TLETVCGTTVYMAPELIERRT 207 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKC-PRYFSAELKDLLHKI 1204 YDG K D+WS GVIL+ L+ GYLPF + + + +I + K + + +DL+ ++ Sbjct: 208 YDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRL 267 Query: 1205 LDPDPSTRIPISRI 1246 L +P R +S++ Sbjct: 268 LAKNPGERPSLSQV 281
>P15791:KCC2D_RAT Calcium/calmodulin-dependent protein kinase type II delta chain -| Rattus norvegicus (Rat) Length = 533 Score = 137 bits (345), Expect = 2e-31 Identities = 83/262 (31%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + TGQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 72 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y V + GGELF IV +E A Q++ ++++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ +Q GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQ--AWFGFAGTPGYLSPEVLRKDP 190 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +P+ RI S K W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>O77708:KCC2D_RABIT Calcium/calmodulin-dependent protein kinase type II delta chain -| Oryctolagus cuniculus (Rabbit) Length = 533 Score = 137 bits (345), Expect = 2e-31 Identities = 83/262 (31%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + TGQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 72 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y V + GGELF IV +E A Q++ ++++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ +Q GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQ--AWFGFAGTPGYLSPEVLRKDP 190 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +P+ RI S K W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q95266:KCC2D_PIG Calcium/calmodulin-dependent protein kinase type II delta chain - Sus| scrofa (Pig) Length = 499 Score = 137 bits (345), Expect = 2e-31 Identities = 83/262 (31%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + TGQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 72 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y V + GGELF IV +E A Q++ ++++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ +Q GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQ--AWFGFAGTPGYLSPEVLRKDP 190 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +P+ RI S K W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q6PHZ2:KCC2D_MOUSE Calcium/calmodulin-dependent protein kinase type II delta chain - Mus| musculus (Mouse) Length = 499 Score = 137 bits (345), Expect = 2e-31 Identities = 83/262 (31%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + TGQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 72 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y V + GGELF IV +E A Q++ ++++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ +Q GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQ--AWFGFAGTPGYLSPEVLRKDP 190 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +P+ RI S K W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q13557:KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II delta chain -| Homo sapiens (Human) Length = 499 Score = 137 bits (345), Expect = 2e-31 Identities = 83/262 (31%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + TGQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 72 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y V + GGELF IV +E A Q++ ++++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ +Q GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQ--AWFGFAGTPGYLSPEVLRKDP 190 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +P+ RI S K W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q2HJF7:KCC2D_BOVIN Calcium/calmodulin-dependent protein kinase type II delta chain - Bos| taurus (Bovine) Length = 488 Score = 137 bits (345), Expect = 2e-31 Identities = 83/262 (31%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + TGQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 72 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y V + GGELF IV +E A Q++ ++++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ +Q GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQ--AWFGFAGTPGYLSPEVLRKDP 190 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +P+ RI S K W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>P28583:CDPK_SOYBN Calcium-dependent protein kinase SK5 - Glycine max (Soybean)| Length = 508 Score = 137 bits (345), Expect = 2e-31 Identities = 90/263 (34%), Positives = 137/263 (52%), Gaps = 8/263 (3%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMR-LVKHP 673 YE+G++LGQG F + A+G A K I K K+ E + REI +M L +H Sbjct: 34 YEVGRKLGQGQFGTTFECTRRASGGKFACKSIPKRKLLCKEDYEDVWREIQIMHHLSEHA 93 Query: 674 NVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRG 853 NV+++ + ++ V+E +GGELF++IV++G +E A R ++ ++ CHS G Sbjct: 94 NVVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKTIVEVVEACHSLG 153 Query: 854 VYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 V HR +DFGLS + G+P YVAPEVL RK Sbjct: 154 VMHRDLKPENFLFDTIDEDAKLKATDFGLSVF---YKPGESFCDVVGSPYYVAPEVL-RK 209 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRI--SKADFKCPRY--FSAELKDL 1192 Y G ++DVWS+GVIL++L++G PF + ++R+I K DF + S KDL Sbjct: 210 LY-GPESDVWSAGVILYILLSGVPPFWAESEPGIFRQILLGKLDFHSEPWPSISDSAKDL 268 Query: 1193 LHKILDPDPSTRIPISRIKKSAW 1261 + K+LD +P TR+ + + W Sbjct: 269 IRKMLDQNPKTRLTAHEVLRHPW 291
>Q60806:PLK3_MOUSE Serine/threonine-protein kinase PLK3 - Mus musculus (Mouse)| Length = 631 Score = 137 bits (344), Expect = 2e-31 Identities = 89/263 (33%), Positives = 129/263 (49%), Gaps = 1/263 (0%) Frame = +2 Query: 485 LMGR-YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRL 661 L GR Y G+ LG+G FA+ Y A + +G A A+K+I + +V K E+I EI + R Sbjct: 58 LSGRTYTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRD 117 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYC 841 ++H ++++ IY LE L + L E R Y Q++S + Y Sbjct: 118 LQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYL 177 Query: 842 HSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSR 1021 H RG+ HR V DFGL+A + Q T CGTP YVAPEVL R Sbjct: 178 HQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQ--RKKTICGTPNYVAPEVLLR 235 Query: 1022 KGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHK 1201 +G+ G +ADVWS G +++ L+ G PF +L E YR I + + P S + LL Sbjct: 236 QGH-GPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAA 294 Query: 1202 ILDPDPSTRIPISRIKKSAWYRR 1270 IL P R I +I + ++ + Sbjct: 295 ILRASPRDRPSIEQILRHDFFTK 317
>Q9UK32:KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 - Homo sapiens (Human)| Length = 745 Score = 137 bits (344), Expect = 2e-31 Identities = 89/296 (30%), Positives = 151/296 (51%), Gaps = 17/296 (5%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLA---TGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 ++E+ K LGQG+F KV+ R GQ A+K++ K + KV + K E ++ V Sbjct: 72 QFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASL-KVRDRVRTKMERDILVEV 130 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP +++L T+ K+Y +L++ +GG++F ++ KE E+ + Y +L A+D+ H Sbjct: 131 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 190 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 G+ +R ++DFGLS + Q+ ++ CGT Y+APEV++R+ Sbjct: 191 QLGIVYRDLKPENILLDEIGHIKLTDFGLS--KESVDQEKKAYSFCGTVEYMAPEVVNRR 248 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 G+ AD WS GV++F ++ G LPF + E I KA P++ SAE + LL + Sbjct: 249 GH-SQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRML 307 Query: 1205 LDPDPSTRI---PISRIKKSAW---------YRRPVEVNAKKT--EPEATHTFSAE 1330 +P+ R+ + IK+ + Y+R V+ K +P+ T F E Sbjct: 308 FKRNPANRLGSEGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPE 363 Score = 116 bits (291), Expect = 3e-25 Identities = 82/266 (30%), Positives = 124/266 (46%), Gaps = 11/266 (4%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YE+ + +G G+++ + T A+K+I+K K IE + MR +HPN Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEIL------MRYGQHPN 479 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L +V +Y V + KGGEL ++I+K+ +E A + + +DY H +GV Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539 Query: 857 YHR----XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 HR + DFG + ++GLL T C T +VAPEVL ++ Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFA--KQLRGENGLLLTPCYTANFVAPEVLMQQ 597 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPF---HETNLIEMYRRISKADFKCP----RYFSAEL 1183 GYD A D+WS GV+ + ++AGY PF E+ RI F S Sbjct: 598 GYDAA-CDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGA 656 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAW 1261 KDLL +L DP R +I K +W Sbjct: 657 KDLLSHMLHMDPHQRYTAEQILKHSW 682
>Q9WUT3:KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 - Mus musculus (Mouse)| Length = 733 Score = 136 bits (343), Expect = 3e-31 Identities = 90/305 (29%), Positives = 151/305 (49%), Gaps = 19/305 (6%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLA---TGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 ++E+ K LGQG++ KV+ R + GQ A+K++ K + KV + K E ++ V Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATL-KVRDRVRSKMERDILAEV 116 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP +++L T+ K+Y +L++ +GG+LF ++ KE E+ + Y +L A+D+ H Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 G+ +R ++DFGLS + D ++ CGT Y+APEV++R+ Sbjct: 177 GLGIIYRDLKPENILLDEEGHIKITDFGLS--KEATDHDKRAYSFCGTIEYMAPEVVNRR 234 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 G+ AD WS GV++F ++ G LPF + E I KA P++ SAE + LL + Sbjct: 235 GHT-QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAEAQSLLRAL 293 Query: 1205 LDPDPSTRI-----PISRIKKSAW---------YRRPVEVNAKKT--EPEATHTFSAEAA 1336 +P R+ + IK+ + YR+ ++ K PE T F E Sbjct: 294 FKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAVGRPEDTFHFDPEFT 353 Query: 1337 SSVST 1351 + T Sbjct: 354 ARTPT 358 Score = 120 bits (301), Expect = 2e-26 Identities = 81/266 (30%), Positives = 130/266 (48%), Gaps = 11/266 (4%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YEI + +G G+++ + AT A+K+I+K K IE + +R +HPN Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPSEEIEIL------LRYGQHPN 468 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L +V +Y V+E +GGEL ++I+++ +E A + + +DY HS+GV Sbjct: 469 IITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQGV 528 Query: 857 YHR----XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 HR + DFG + ++GLL T C T +VAPEVL R+ Sbjct: 529 VHRDLKPSNILYMDESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQ 586 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPF---HETNLIEMYRRISKADFKCP----RYFSAEL 1183 GYD A DVWS G++L+ ++AG+ PF + E+ RI + S Sbjct: 587 GYDAA-CDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAA 645 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAW 1261 KD++ K+L DP R+ ++ K W Sbjct: 646 KDVVSKMLHVDPQQRLTAVQVLKHPW 671
>P27466:KCC1_YEAST Calcium/calmodulin-dependent protein kinase I - Saccharomyces| cerevisiae (Baker's yeast) Length = 446 Score = 136 bits (343), Expect = 3e-31 Identities = 85/267 (31%), Positives = 138/267 (51%), Gaps = 11/267 (4%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKD--KVTKVGLIEQIKREISVMRLVK 667 +Y GK LG GTF V A+N TG+ VA+K++ K K KV L E + E+ +++ + Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQL-EALYDELDILQRLH 94 Query: 668 HPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHS 847 HPN++ + +K K Y + + AKGGELF++I+K+GK E+ A R +++SA+ Y HS Sbjct: 95 HPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHS 154 Query: 848 RGVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLS 1018 + + HR V+DFG++ + LL+ G+ YVAPEVL+ Sbjct: 155 QNIVHRDLKPENLLYIDKSDESPLVVADFGIA--KRLKSDEELLYKPAGSLGYVAPEVLT 212 Query: 1019 RKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRY------FSAE 1180 + G+ G D+WS GVI + L+ GY F + + + ++ + S + Sbjct: 213 QDGH-GKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNK 271 Query: 1181 LKDLLHKILDPDPSTRIPISRIKKSAW 1261 K + K L+ DPS R + + + W Sbjct: 272 AKQFILKALNLDPSKRPTAAELLEDPW 298
>Q15349:KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 - Homo sapiens (Human)| Length = 733 Score = 135 bits (341), Expect = 5e-31 Identities = 90/305 (29%), Positives = 151/305 (49%), Gaps = 19/305 (6%) Frame = +2 Query: 494 RYEIGKQLGQGTFAKVYYARNLA---TGQAVAIKMINKDKVTKVGLIEQIKREISVMRLV 664 ++E+ K LGQG++ KV+ R + GQ A+K++ K + KV + K E ++ V Sbjct: 58 QFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATL-KVRDRVRSKMERDILAEV 116 Query: 665 KHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCH 844 HP +++L T+ K+Y +L++ +GG+LF ++ KE E+ + Y +L A+D+ H Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176 Query: 845 SRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 S G+ +R ++DFGLS + D ++ CGT Y+APEV++R+ Sbjct: 177 SLGIIYRDLKPENILLDEEGHIKITDFGLS--KEAIDHDKRAYSFCGTIEYMAPEVVNRR 234 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKI 1204 G+ AD WS GV++F ++ G LPF + E I KA P++ S E + LL + Sbjct: 235 GHT-QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRAL 293 Query: 1205 LDPDPSTRI-----PISRIKK---------SAWYRRPVEVNAKKT--EPEATHTFSAEAA 1336 +P R+ + IK+ + YR+ ++ K PE T F E Sbjct: 294 FKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFT 353 Query: 1337 SSVST 1351 + T Sbjct: 354 ARTPT 358 Score = 117 bits (293), Expect = 2e-25 Identities = 81/266 (30%), Positives = 128/266 (48%), Gaps = 11/266 (4%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 YEI + +G G+++ + AT A+K+I+K K IE + +R +HPN Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEIL------LRYGQHPN 468 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 ++ L +V +Y V+E +GGEL ++I+++ +E A + +DY HS+GV Sbjct: 469 IITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGV 528 Query: 857 YHR----XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRK 1024 HR V DFG + +GLL T C T +VAPEVL R+ Sbjct: 529 VHRDLKPSNILYRDESGSPESIRVCDFGFA--KQLRAGNGLLMTPCYTANFVAPEVLKRQ 586 Query: 1025 GYDGAKADVWSSGVILFVLVAGYLPF---HETNLIEMYRRISKADFKCP----RYFSAEL 1183 GYD A D+WS G++L+ ++AG+ PF + E+ RI + S Sbjct: 587 GYDAA-CDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAA 645 Query: 1184 KDLLHKILDPDPSTRIPISRIKKSAW 1261 KD++ K+L DP R+ ++ K W Sbjct: 646 KDVVSKMLHVDPHQRLTAMQVLKHPW 671
>P16912:KDC2_DROME Protein kinase DC2 - Drosophila melanogaster (Fruit fly)| Length = 583 Score = 135 bits (341), Expect = 5e-31 Identities = 77/276 (27%), Positives = 141/276 (51%), Gaps = 7/276 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y+I K +G GTF +V R+ + + A+K++ +V ++ IE +K E +++R ++HP Sbjct: 274 YQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPF 333 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 V+ L S +Y + +Y GGELF + GK + Y +++SA++Y HS + Sbjct: 334 VISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQI 393 Query: 857 YHRXXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKGYDG 1036 +R ++DFG + + T CGTP Y+APE++ KG++ Sbjct: 394 VYRDLKPENLLINRDGHLKITDFGFA-----KKLRDRTWTLCGTPEYIAPEIIQSKGHNK 448 Query: 1037 AKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKADFKCPRYFSAELKDLLHKILDPD 1216 A D W+ GV+++ ++ GY PF++ +Y +I + R+ KDL+ K+L D Sbjct: 449 A-VDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVND 507 Query: 1217 PSTRIPISR-----IKKSAWYRRP--VEVNAKKTEP 1303 + R+ + +K+ W++ +V +KK +P Sbjct: 508 RTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKP 543
>P11275:KCC2A_RAT Calcium/calmodulin-dependent protein kinase type II alpha chain -| Rattus norvegicus (Rat) Length = 478 Score = 135 bits (341), Expect = 5e-31 Identities = 83/262 (31%), Positives = 138/262 (52%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + GQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 71 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y + + GGELF IV +E A Q++ A+ +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ + +Q GTP Y++PEVL + Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ--AWFGFAGTPGYLSPEVLRKDP 189 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +PS RI + K W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>Q5RCC4:KCC2A_PONPY Calcium/calmodulin-dependent protein kinase type II alpha chain -| Pongo pygmaeus (Orangutan) Length = 478 Score = 135 bits (341), Expect = 5e-31 Identities = 83/262 (31%), Positives = 138/262 (52%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + GQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 71 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y + + GGELF IV +E A Q++ A+ +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ + +Q GTP Y++PEVL + Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ--AWFGFAGTPGYLSPEVLRKDP 189 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +PS RI + K W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>P11798:KCC2A_MOUSE Calcium/calmodulin-dependent protein kinase type II alpha chain - Mus| musculus (Mouse) Length = 478 Score = 135 bits (341), Expect = 5e-31 Identities = 83/262 (31%), Positives = 138/262 (52%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + GQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 71 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y + + GGELF IV +E A Q++ A+ +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ + +Q GTP Y++PEVL + Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ--AWFGFAGTPGYLSPEVLRKDP 189 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +PS RI + K W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>Q9UQM7:KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II alpha chain -| Homo sapiens (Human) Length = 478 Score = 135 bits (341), Expect = 5e-31 Identities = 83/262 (31%), Positives = 138/262 (52%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V + GQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 71 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y + + GGELF IV +E A Q++ A+ +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ + +Q GTP Y++PEVL + Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ--AWFGFAGTPGYLSPEVLRKDP 189 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +PS RI + K W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>P53681:CRK_DAUCA CDPK-related protein kinase - Daucus carota (Carrot)| Length = 602 Score = 135 bits (341), Expect = 5e-31 Identities = 86/275 (31%), Positives = 147/275 (53%), Gaps = 12/275 (4%) Frame = +2 Query: 494 RYEIGKQLGQGTFA---KVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMR-L 661 ++E+G+++G+G F + + + GQ VA+K+I K K+T IE ++RE+ ++R L Sbjct: 147 KFEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIEDVRREVKILRAL 206 Query: 662 VKHPNVLQLFEVMATKSKIYFVLEYAKGGELFNKIV-KEGKLNEDAARRYFHQLISAIDY 838 H N++Q ++ + +Y V+E +GGEL ++I+ + GK ED A+ Q+++ + + Sbjct: 207 TGHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVAF 266 Query: 839 CHSRGVYHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPE 1009 CH +GV HR DFGLS D + D L+ G+ YVAPE Sbjct: 267 CHLQGVVHRDLKPENFLFKSKDEDSQLKAIDFGLS---DYVKPDERLNDIVGSAYYVAPE 323 Query: 1010 VLSRKGYDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKAD--FKCPRY--FSA 1177 VL R +ADVWS GVI ++L+ G PF ++R + KA+ F P + S+ Sbjct: 324 VLHRS--YSTEADVWSIGVISYILLCGSRPFWARTESGIFRAVLKANLSFDEPPWPSVSS 381 Query: 1178 ELKDLLHKILDPDPSTRIPISRIKKSAWYRRPVEV 1282 E KD + ++L+ DP R+ ++ +W + ++ Sbjct: 382 EAKDFVKRLLNKDPRKRMTAAQALCHSWIKNSNDI 416
>Q6DGS3:KCC2D_DANRE Calcium/calmodulin-dependent protein kinase type II delta chain -| Danio rerio (Zebrafish) (Brachydanio rerio) Length = 493 Score = 135 bits (340), Expect = 7e-31 Identities = 82/262 (31%), Positives = 139/262 (53%), Gaps = 7/262 (2%) Frame = +2 Query: 497 YEIGKQLGQGTFAKVYYARNLATGQAVAIKMINKDKVTKVGLIEQIKREISVMRLVKHPN 676 Y++ ++LG+G F+ V +++GQ A K+IN K++ ++++RE + RL+KHPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKISSGQEYAAKIINTKKLSARDH-QKLEREARICRLLKHPN 71 Query: 677 VLQLFEVMATKSKIYFVLEYAKGGELFNKIVKEGKLNEDAARRYFHQLISAIDYCHSRGV 856 +++L + ++ + Y V + GGELF IV +E A Q++ ++ +CH G+ Sbjct: 72 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHVNGI 131 Query: 857 YHR---XXXXXXXXXXXXXXXXVSDFGLSALADCARQDGLLHTTCGTPAYVAPEVLSRKG 1027 HR ++DFGL+ +Q GTP Y++PEVL + Sbjct: 132 VHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQ--AWFGFAGTPGYLSPEVLRKDP 189 Query: 1028 YDGAKADVWSSGVILFVLVAGYLPFHETNLIEMYRRISKA--DFKCPRY--FSAELKDLL 1195 Y G D+W+ GVIL++L+ GY PF + + +Y++I DF P + + E KDL+ Sbjct: 190 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 1196 HKILDPDPSTRIPISRIKKSAW 1261 +K+L +PS RI + K W Sbjct: 249 NKMLTINPSKRITAAEAPKHPW 270
>P50526:SSP1_SCHPO Serine/threonine-protein kinase ssp1 - Schizosaccharomyces pombe| (Fission yeast) Length = 652 Score = 135 bits (339), Expect = 9e-31 Identities = 96/287 (33%), Positives = 148/287 (51%), Gaps = 19/287 (6%) Frame = +2 Query: 458 DRMDERRTILMGRYEIGKQLGQGTFAKVYYARNLATGQAVAIKMINK-DKVTKVGLI--- 625 DR R+ I YEI K+LG+G KV R+ T + +AIK+I K ++ K+G Sbjct: 124 DRFSGRKYI--NHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANAS 181 Query: 626 ---EQIKREISVMRLVKHPNVLQLFEVM--ATKSKIYFVLEYAKGGELFNKIVKEGKLNE 790 E+++REI++++ HPNV++L EV+ + +K+Y VLEY GGE+ L+ Sbjct: 182 SQKEKVRREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSI 241 Query: 791 DAARRYFHQLISAIDYCHSRGVYHRXXXXXXXXXXXXXXXXVSDFGLSALADCA---RQD 961 AR+YF ++ ++Y H +G+ HR +SDFG+S +A+ D Sbjct: 242 SEARQYFRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDND 301 Query: 962 GLLHTTCGTPAYVAPEV----LSRKGYDGAKA-DVWSSGVILFVLVAGYLPFHETNLIEM 1126 L T GTPA+ APE+ L R ++A DVW+ GV LF L+ G PF+ + E+ Sbjct: 302 VELAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNASMEYEL 361 Query: 1127 YRRISKADFKCPRY--FSAELKDLLHKILDPDPSTRIPISRIKKSAW 1261 + +I P E +DLL ++L DP RI + +K W Sbjct: 362 FDKIVNERLNIPSTPDIGEEGRDLLKRLLCKDPEQRITLVEVKLHPW 408 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 359,002,012 Number of extensions: 7580024 Number of successful extensions: 27180 Number of sequences better than 10.0: 2364 Number of HSP's gapped: 23292 Number of HSP's successfully gapped: 2516 Length of query: 721 Length of database: 100,686,439 Length adjustment: 121 Effective length of query: 600 Effective length of database: 67,496,744 Effective search space: 40498046400 Effective search space used: 40498046400 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
