ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf17p19 |
|---|---|
| Clone Library Name | barley_pub |
>Q2LZZ7:ST38L_DROPS Serine/threonine-protein kinase 38-like - Drosophila pseudoobscura| (Fruit fly) Length = 458 Score = 409 bits (1050), Expect = e-113 Identities = 221/456 (48%), Positives = 293/456 (64%), Gaps = 4/456 (0%) Frame = +3 Query: 393 SSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVP-AEEQNNILKHLEK 569 S T K AK +EN+Y + +RK+R LE +L+D + ++ Q L+H +K Sbjct: 16 SDHTLDKATKAKVTLENYYSNLVTQYGERKQRLAKLEAQLKDESLTESQRQEKRLQHAQK 75 Query: 570 KETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQV 749 ETEY+RL+R ++GVEDFE L +IGRGAFGEVRL ++K + VYAMK L+K++ML + QV Sbjct: 76 -ETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQV 134 Query: 750 EHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKF 929 HV+AER++L E D ++VK+YYSFQD LYLIME+LPGGDMMTLLM+KDTL+E+ +F Sbjct: 135 AHVRAERDVLVEADHQWVVKMYYSFQDQVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQF 194 Query: 930 YIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYT 1109 YI+ET LAI+SIHK +IHRDIKPDN FGLC L S+ + Y Sbjct: 195 YISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDF----YR 250 Query: 1110 PGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGY 1289 AKP D +P KR + W++NRR LAYSTVGTPDYIAPEV L+ GY Sbjct: 251 DLSQAKP-SDFIGTCASPMDSKRRAES----WKRNRRALAYSTVGTPDYIAPEVFLQTGY 305 Query: 1290 GMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISK 1469 G CDWWSLG IMYEML+GYPPF S++P T RK++NWR L FP E +S E K+ I K Sbjct: 306 GPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIIK 365 Query: 1470 LLCNVEQRLGT-KGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETGA 1646 C ++RLG+ +G ++K+ +FRGV WE + + AA EV DT NF++F + Sbjct: 366 FCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVEVRSIDDTSNFDEFPDVSL 425 Query: 1647 QVQSS--SKAGPWRKMLPSKDANFVGYTYKNFEIVN 1748 ++ S+ + G +KD F+ YTYK FE+ N Sbjct: 426 EIPSAPIPQGGE-----IAKDWVFINYTYKRFEVRN 456
>Q9NBK5:ST38L_DROME Serine/threonine-protein kinase 38-like - Drosophila melanogaster| (Fruit fly) Length = 463 Score = 407 bits (1046), Expect = e-113 Identities = 219/456 (48%), Positives = 291/456 (63%), Gaps = 4/456 (0%) Frame = +3 Query: 393 SSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVP-AEEQNNILKHLEK 569 S T K AK +EN+Y + +RK+R LE +L+D + A+ Q L+H +K Sbjct: 17 SDHTLDKATKAKVTLENYYSNLVTQYGERKQRLAKLEAQLKDESLSEAQRQEKRLQHAQK 76 Query: 570 KETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQV 749 ETEY+RL+R ++GVEDFE L +IGRGAFGEVRL ++K + VYAMK L+K++ML + QV Sbjct: 77 -ETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQV 135 Query: 750 EHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKF 929 HV+AER++L E D ++VK+YYSFQD LYLIME+LPGGDMMTLLM+KDTL+E+ +F Sbjct: 136 AHVRAERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQF 195 Query: 930 YIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYT 1109 YI+ET LAI+SIHK +IHRDIKPDN FGLC L S+ + Y Sbjct: 196 YISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDF----YR 251 Query: 1110 PGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGY 1289 AKP D + S + + W++NRR LAYSTVGTPDYIAPEV L+ GY Sbjct: 252 DLSQAKP-SDFIGTCASLSCSPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGY 310 Query: 1290 GMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISK 1469 G CDWWSLG IMYEML+GYPPF S++P T RK++NWR L FP E +S E K+ I Sbjct: 311 GPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIIN 370 Query: 1470 LLCNVEQRLGT-KGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETGA 1646 C ++RLG+ +G ++K+ +FRGV WE + + AA EV DT NF++F + Sbjct: 371 FCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVEVRSIDDTSNFDEFPDVSL 430 Query: 1647 QVQSS--SKAGPWRKMLPSKDANFVGYTYKNFEIVN 1748 ++ S+ + G +KD F+ YTYK FE+ N Sbjct: 431 EIPSAPIPQGGE-----IAKDWVFINYTYKRFEVRN 461
>Q5R8M1:STK38_PONPY Serine/threonine-protein kinase 38 - Pongo pygmaeus (Orangutan)| Length = 465 Score = 402 bits (1034), Expect = e-111 Identities = 208/453 (45%), Positives = 292/453 (64%), Gaps = 4/453 (0%) Frame = +3 Query: 393 SSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKK 572 S+ TK++V K +EN Y + ++R+ R+ LE+ +++ + EE+ +K Sbjct: 13 SNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARK 72 Query: 573 ETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVE 752 ETE++RL+R ++G+EDFE L +IGRGAFGEVRL ++K + VYAMK L+K++ML + QV Sbjct: 73 ETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVG 132 Query: 753 HVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFY 932 H++AER++L E DS ++VK++YSFQD LYLIME+LPGGDMMTLLM+KDTLTE+E +FY Sbjct: 133 HIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFY 192 Query: 933 IAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSN----FPNLNEP 1100 IAETVLAI+SIH+ +IHRDIKPDN FGLC L ++ + NLN Sbjct: 193 IAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNH- 251 Query: 1101 DYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLK 1280 LP + + N ++ ++ + W++NRR LA+STVGTPDYIAPEV ++ Sbjct: 252 ---------SLPSDFT-FQNMNSKRKAET-----WKRNRRQLAFSTVGTPDYIAPEVFMQ 296 Query: 1281 KGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDL 1460 GY CDWWSLG IMYEML+GYPPF SE P T +K++NW+ L FP E +S + KDL Sbjct: 297 TGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDL 356 Query: 1461 ISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEET 1640 I + C E R+G G EIK++++F GV WE + + AA E+ DT NF++F E+ Sbjct: 357 ILRFCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPES 416 Query: 1641 GAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFE 1739 + + + +KD F+ YTYK FE Sbjct: 417 DILKPTVATSNHPETDYKNKDWVFINYTYKRFE 449
>Q15208:STK38_HUMAN Serine/threonine-protein kinase 38 - Homo sapiens (Human)| Length = 465 Score = 402 bits (1034), Expect = e-111 Identities = 208/453 (45%), Positives = 292/453 (64%), Gaps = 4/453 (0%) Frame = +3 Query: 393 SSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKK 572 S+ TK++V K +EN Y + ++R+ R+ LE+ +++ + EE+ +K Sbjct: 13 SNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARK 72 Query: 573 ETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVE 752 ETE++RL+R ++G+EDFE L +IGRGAFGEVRL ++K + VYAMK L+K++ML + QV Sbjct: 73 ETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVG 132 Query: 753 HVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFY 932 H++AER++L E DS ++VK++YSFQD LYLIME+LPGGDMMTLLM+KDTLTE+E +FY Sbjct: 133 HIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFY 192 Query: 933 IAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSN----FPNLNEP 1100 IAETVLAI+SIH+ +IHRDIKPDN FGLC L ++ + NLN Sbjct: 193 IAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNH- 251 Query: 1101 DYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLK 1280 LP + + N ++ ++ + W++NRR LA+STVGTPDYIAPEV ++ Sbjct: 252 ---------SLPSDFT-FQNMNSKRKAET-----WKRNRRQLAFSTVGTPDYIAPEVFMQ 296 Query: 1281 KGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDL 1460 GY CDWWSLG IMYEML+GYPPF SE P T +K++NW+ L FP E +S + KDL Sbjct: 297 TGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDL 356 Query: 1461 ISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEET 1640 I + C E R+G G EIK++++F GV WE + + AA E+ DT NF++F E+ Sbjct: 357 ILRFCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPES 416 Query: 1641 GAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFE 1739 + + + +KD F+ YTYK FE Sbjct: 417 DILKPTVATSNHPETDYKNKDWVFINYTYKRFE 449
>Q9Y2H1:ST38L_HUMAN Serine/threonine-protein kinase 38-like - Homo sapiens (Human)| Length = 464 Score = 402 bits (1033), Expect = e-111 Identities = 209/449 (46%), Positives = 283/449 (63%) Frame = +3 Query: 393 SSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKK 572 S+ T+++V AK +EN Y + ++R+ R+ LE +++ + EE+ +K Sbjct: 14 SNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARK 73 Query: 573 ETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVE 752 ETE++RL+R ++G++DFE L +IGRGAFGEVRL ++K + +YAMK L+KS+ML + QV Sbjct: 74 ETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVA 133 Query: 753 HVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFY 932 H++AER++L E D A++VK++YSFQD LYLIME+LPGGDMMTLLM+KDTLTE+E +FY Sbjct: 134 HIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFY 193 Query: 933 IAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTP 1112 I+ETVLAI++IH+ +IHRDIKPDN FGLC L + + ++ Sbjct: 194 ISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKA-----HRTEFYR 248 Query: 1113 GKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYG 1292 P D + + N T W+KNRR LAYSTVGTPDYIAPEV ++ GY Sbjct: 249 NLTHNPPSDFSFQNMNSKRKAET-------WKKNRRQLAYSTVGTPDYIAPEVFMQTGYN 301 Query: 1293 MECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKL 1472 CDWWSLG IMYEML+GYPPF SE P T RK++NW+ L FP E +S + KDLI + Sbjct: 302 KLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRF 361 Query: 1473 LCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETGAQV 1652 + E R+G G EIK H +F GV WE + + AA E+ DT NF+ F E+ Sbjct: 362 CIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDILQ 421 Query: 1653 QSSSKAGPWRKMLPSKDANFVGYTYKNFE 1739 + P K SKD F+ YTYK FE Sbjct: 422 PVPNTTEPDYK---SKDWVFLNYTYKRFE 447
>Q6TGC6:CBK1_PNECA Serine/threonine-protein kinase CBK1 - Pneumocystis carinii| Length = 507 Score = 401 bits (1030), Expect = e-111 Identities = 207/464 (44%), Positives = 299/464 (64%), Gaps = 8/464 (1%) Frame = +3 Query: 378 VDDAPS--SATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNI 551 V DA S T ++ A+ K +E+ YK ++ +R +RR E KL E + Sbjct: 43 VRDASSFTKTTHERAASVKLKLEHLYKVTVEQTVERNQRRMDFEAKLAQDRGSEERKKRQ 102 Query: 552 LKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEM 731 L L +KE++++RL+R K+ + DF + +IG+GAFGEVRL ++ + +YAMK L KSEM Sbjct: 103 LNSLGQKESQFLRLRRTKLSLNDFHTVKVIGKGAFGEVRLVQKIDTGKIYAMKTLLKSEM 162 Query: 732 LRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLT 911 ++ Q+ HVKAER++LAE DS ++V LYYSFQD ++LYLIME+LPGGD+MT+L++ DT + Sbjct: 163 FKKDQLAHVKAERDVLAESDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIKYDTFS 222 Query: 912 EDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLC----KPLDSSN 1079 ED +FYIAE +LAIE++HK +IHRDIKPDN FGL K D++ Sbjct: 223 EDVTRFYIAECILAIEAVHKLGFIHRDIKPDNILIDKTGHIKLSDFGLSMGFHKTHDNAY 282 Query: 1080 FPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYI 1259 + L E + S + + + + +++++ W+KNRR++AYSTVGTPDYI Sbjct: 283 YQRLFESKINTSTSS----TQNSLMVDTISLTMSSKDKIATWKKNRRIMAYSTVGTPDYI 338 Query: 1260 APEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKL 1439 APE+ + GYG ECDWWSLGAIM+E L+G+PPF SE+ T RKI+NWR +L FPE+ L Sbjct: 339 APEIFTQHGYGQECDWWSLGAIMFECLIGWPPFCSENAHETYRKIINWRENLYFPEDLHL 398 Query: 1440 SSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQN 1619 S+E +DLI KLL + +QRLG GA++IK H +FRGV W+ + ++ A F+P++ DT Sbjct: 399 SAEAEDLIRKLLTSADQRLGRYGANDIKLHPFFRGVNWDTIREINAPFIPQLKSITDTSY 458 Query: 1620 FEKFEETGAQVQSSSKAGPWRKMLPSKDAN--FVGYTYKNFEIV 1745 FE+ +T + +S K+ D N FVGYTYK F+++ Sbjct: 459 FEEI-DTIPNITMNSPPVLQNKIPSDVDQNLAFVGYTYKRFDMM 501
>Q91VJ4:STK38_MOUSE Serine/threonine-protein kinase 38 - Mus musculus (Mouse)| Length = 465 Score = 397 bits (1021), Expect = e-110 Identities = 207/453 (45%), Positives = 289/453 (63%), Gaps = 4/453 (0%) Frame = +3 Query: 393 SSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKK 572 S+ TK++V K +EN Y + ++R+ R+ LE+ +++ + EE+ +K Sbjct: 13 SNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARK 72 Query: 573 ETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVE 752 ETE++RL+R ++G+EDFE L +IGRGAFGEVRL ++K + VYAMK L+K++ML + QV Sbjct: 73 ETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVG 132 Query: 753 HVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFY 932 H++AER++L E DS ++VK++YSFQD LYLIME+LPGGDMMTLLM+KDTLTE+E +FY Sbjct: 133 HIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFY 192 Query: 933 IAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSN----FPNLNEP 1100 IAETVLAI+SIH+ +IHRDIKPDN FGLC L ++ + NLN Sbjct: 193 IAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNH- 251 Query: 1101 DYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLK 1280 LP + + N ++ ++ + W++NRR LA+STVGTPDYIAPEV ++ Sbjct: 252 ---------SLPSDFT-FQNMNSKRKAET-----WKRNRRQLAFSTVGTPDYIAPEVFMQ 296 Query: 1281 KGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDL 1460 GY CDWWSLG IMYEML+GYPPF SE P T +K++NW+ L FP E +S + K L Sbjct: 297 TGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPVSEKAKGL 356 Query: 1461 ISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEET 1640 I + C E R+G G EIK + +F GV WE + + AA E+ DT NF++F E+ Sbjct: 357 ILRFCCEWEHRIGAPGVEEIKNNLFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPES 416 Query: 1641 GAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFE 1739 + + + +KD F+ YTYK FE Sbjct: 417 DILKPTVTTSSHPETDYKNKDWVFINYTYKRFE 449
>P53894:CBK1_YEAST Serine/threonine-protein kinase CBK1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 756 Score = 397 bits (1021), Expect = e-110 Identities = 214/478 (44%), Positives = 303/478 (63%), Gaps = 26/478 (5%) Frame = +3 Query: 384 DAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHL 563 D + T+ K AA K IEN Y++ +K +R ERR LE +L E ++ L L Sbjct: 273 DLLTKGTQDKAAAVKLKIENFYQSSVKYAIERNERRVELETELTSHNWSEERKSRQLSSL 332 Query: 564 EKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRG 743 KKE++++RL+R ++ +EDF + +IG+GAFGEVRL ++K + +YAMK L KSEM ++ Sbjct: 333 GKKESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKD 392 Query: 744 QVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEA 923 Q+ HVKAER++LA DS ++V LYYSFQD ++LYLIME+LPGGD+MT+L+R TED Sbjct: 393 QLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVT 452 Query: 924 KFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLC----KPLDSSNFPNL 1091 +FY+AE +LAIE+IHK +IHRDIKPDN FGL K DS+ + L Sbjct: 453 RFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKL 512 Query: 1092 NEPDYTPGKGAKPLPDNTSRLTNPSAPKR------------TQQEQLSHWQKNRRMLAYS 1235 + D +KP N + T +A KR + ++Q+ W+K+RR++AYS Sbjct: 513 LQQDEATNGISKPGTYNAN--TTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYS 570 Query: 1236 TVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHL 1415 TVGTPDYIAPE+ L +GYG ECDWWSLGAIMYE L+G+PPF SE P T RKI+N+ L Sbjct: 571 TVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTL 630 Query: 1416 KFPEEAKLSSETKDLISKLLCNVEQRLGTK-GAHEIKAHTWFRGVQWEKLYQMKAAFVPE 1592 +FP++ +S E +DLI +LL + +QRLG GA EIK+H +FRGV W + Q++A ++P+ Sbjct: 631 QFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAPYIPK 690 Query: 1593 VNGELDTQNF-----EKFEETGAQVQSSSKAGPWRKMLPS----KDANFVGYTYKNFE 1739 ++ DT+ F E ++ A Q++ + K S +D F+GYTY F+ Sbjct: 691 LSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTYSRFD 748
>Q6CFS5:CBK1_YARLI Serine/threonine-protein kinase CBK1 - Yarrowia lipolytica (Candida| lipolytica) Length = 588 Score = 396 bits (1017), Expect = e-109 Identities = 212/487 (43%), Positives = 303/487 (62%), Gaps = 7/487 (1%) Frame = +3 Query: 300 QKFQPRDKSKSPAVPASHGKDPGKPPVDDAPSSATKQKVAAAKQYIENHYKTQMKSLQDR 479 Q+ QP+ +S + P+ + +P D S + + Q I +YK ++ +R Sbjct: 104 QQQQPQQQSVAQQQPSDYVNFTPRP---DLLSKTARDRAHNTTQVISTYYKGIVQHAIER 160 Query: 480 KERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFG 659 +RR E ++ A E +N +L + KKET Y+R++R +M +EDF + +IG+GAFG Sbjct: 161 HQRRSAAEASVEQA-TSEERRNRVLTNYGKKETAYLRMRRTRMALEDFVTVKVIGKGAFG 219 Query: 660 EVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEF 839 EVRL +++ + +YAMK + K EM + Q HVKAER++LA+ DS +IV LY+SFQDD + Sbjct: 220 EVRLVQKRDNGKIYAMKTMLKKEMDMKEQWAHVKAERDVLADSDSPWIVSLYFSFQDDLY 279 Query: 840 LYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXX 1019 LYLIME+LPGGD+MT+L++ D +ED +FYIAE VLAIE+IHK +IHRDIKPDN Sbjct: 280 LYLIMEFLPGGDLMTMLIKYDVFSEDITRFYIAECVLAIEAIHKLGFIHRDIKPDNILID 339 Query: 1020 XXXXXXXXXFGLC----KPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQ 1187 FGL K S+ + L + + P NT+R + + T + Sbjct: 340 KTGHIKLSDFGLSTGFHKTHSSAYWKKLKDGTSSNPATQMGPPQNTNRQSTYDSIHLTMR 399 Query: 1188 EQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSE 1367 +Q+S W+KNRR++AYSTVGTPDYIAPE+ + +GYG ECDWWSLGAIM+E LVG+PPF SE Sbjct: 400 QQISTWRKNRRLMAYSTVGTPDYIAPEIFVHQGYGQECDWWSLGAIMFECLVGWPPFCSE 459 Query: 1368 DPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLG-TKGAHEIKAHTWFRG 1544 P T KI+NWR L+FP++ LS E++DLI +LL + E RLG GA+EIK+H +FRG Sbjct: 460 QPRETYHKIINWRETLQFPDDVHLSPESEDLIRRLLTSSENRLGRIGGANEIKSHPFFRG 519 Query: 1545 VQWEKLYQMKAAFVPEVNGELDTQNF--EKFEETGAQVQSSSKAGPWRKMLPSKDANFVG 1718 V W + + A FVP+++ DT F ++ + Q SS++ S D F+G Sbjct: 520 VDWSSIREFNAPFVPKLSSITDTSYFPTDELGDVSEYPQQSSRSD------RSSDLPFIG 573 Query: 1719 YTYKNFE 1739 YT+ F+ Sbjct: 574 YTFSRFD 580
>Q754N7:CBK1_ASHGO Serine/threonine-protein kinase CBK1 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 719 Score = 395 bits (1014), Expect = e-109 Identities = 209/478 (43%), Positives = 298/478 (62%), Gaps = 29/478 (6%) Frame = +3 Query: 393 SSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKK 572 S +T++K AA K +EN Y++ + +R +RR LE +L E +N L L KK Sbjct: 234 SKSTQEKAAAVKLKVENFYQSSVNHAIERNQRRVELESQLLSHGWSEERKNRQLSSLGKK 293 Query: 573 ETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVE 752 E++++RL+R ++ +EDF + +IG+GAFGEVRL ++K + +YAMK L KSEM ++ Q+ Sbjct: 294 ESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLA 353 Query: 753 HVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFY 932 HVKAER++LA DS ++V LYYSFQD ++LYLIME+LPGGD+MT+L+R TED +FY Sbjct: 354 HVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFY 413 Query: 933 IAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLC----KPLDSSNFPNLNEP 1100 +AE +LAIE+IHK +IHRDIKPDN FGL K DS+ + L + Sbjct: 414 MAECILAIEAIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQE 473 Query: 1101 DY------------TPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 D G G + + L + T ++Q+ W+K+RR++AYSTVG Sbjct: 474 DEQQQNGGNMGKYPASGGGGNGGGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVG 533 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TPDYIAPE+ L +GYG ECDWWSLGAIMYE L+G+PPF SE P T RKI+N+ L FP Sbjct: 534 TPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLVFP 593 Query: 1425 EEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGE 1604 ++ +S E +DLI +LL + ++RLG GA+EIK H +FRGV WE + Q+ A ++P+++ Sbjct: 594 DDIHISYEAEDLIRRLLSHADERLGRHGANEIKNHPFFRGVDWETIRQVGAPYIPKLSSV 653 Query: 1605 LDTQNF-----EKFEETGAQVQSSSKAGPWRKMLPS--------KDANFVGYTYKNFE 1739 DT+ F E ++ A Q++ + K S +D F+GYTY F+ Sbjct: 654 TDTRFFPTDELENVPDSPAMAQAAKQREQMLKQGGSAANTAQAKEDLPFIGYTYSRFD 711
>Q6FP74:CBK1_CANGA Serine/threonine-protein kinase CBK1 - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 773 Score = 393 bits (1009), Expect = e-108 Identities = 210/475 (44%), Positives = 300/475 (63%), Gaps = 23/475 (4%) Frame = +3 Query: 384 DAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHL 563 D S +T+ K AA K +EN+Y+ +K +R ERR LE +L E L L Sbjct: 291 DLLSKSTQDKAAAVKLKVENYYQQSVKYAIERNERRVELETELGSHNWSEERNARQLASL 350 Query: 564 EKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRG 743 KKE++++RL+R ++ +EDF + +IG+GAFGEVRL ++K + +YAMK L KSEM ++ Sbjct: 351 GKKESQFLRLRRTRLSLEDFHTVQVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKD 410 Query: 744 QVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEA 923 Q+ HVKAER++LA DS +IV LYYSFQD ++LYLIME+LPGGD+MT+L+R TED Sbjct: 411 QLAHVKAERDVLAGTDSPWIVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVT 470 Query: 924 KFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLC----KPLDSSNFPNL 1091 +FY+AE +LAIE+IHK +IHRDIKPDN FGL K DS+ + L Sbjct: 471 RFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKL 530 Query: 1092 NEPDYTPGKGAKP------LPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPD 1253 + D K P + + + + + ++Q+ W+K+RR++AYSTVGTPD Sbjct: 531 LQQDEATTKNGAPNDAGDGSNNRQTMIVDSINLTMSNRQQIQTWRKSRRLMAYSTVGTPD 590 Query: 1254 YIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEA 1433 YIAPE+ L +GYG +CDWWSLGAIMYE L+G+PPF SE P T RKI+N+ L+FPE+ Sbjct: 591 YIAPEIFLYQGYGQDCDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPEDV 650 Query: 1434 KLSSETKDLISKLLCNVEQRLGTK-GAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELD 1610 +S E +DLI +LL + QRLG + GA EIK+H +FRGV W + Q++A ++P+++ D Sbjct: 651 HISYEAEDLIRRLLTHSNQRLGRQGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITD 710 Query: 1611 TQNF-----EKFEETGAQVQSSSKAGPWRK--MLPS-----KDANFVGYTYKNFE 1739 T+ F E ++ A Q++ + K + P+ +D F+GYTY F+ Sbjct: 711 TRFFPTDELENVPDSPAMAQAAKQREQMMKNGVNPNQNQVKEDLPFIGYTYSRFD 765
>Q7TSE6:ST38L_MOUSE Serine/threonine-protein kinase 38-like - Mus musculus (Mouse)| Length = 464 Score = 391 bits (1005), Expect = e-108 Identities = 203/449 (45%), Positives = 281/449 (62%) Frame = +3 Query: 393 SSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKK 572 S+ T+++V AK +EN Y + ++R+ R+ LE +++ + EE+ +K Sbjct: 14 SNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARK 73 Query: 573 ETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVE 752 ETE++RL+R ++G++DFE L +I RGAFGEVRL ++K + +YAMK L+K++ML + QV Sbjct: 74 ETEFLRLKRTRLGLDDFESLKVIARGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVA 133 Query: 753 HVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFY 932 H++AER++L E D A++VK++YSFQD LYLIME+LPGGDMMTLLM+KDTLTE+E +FY Sbjct: 134 HIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFY 193 Query: 933 IAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTP 1112 I+ETVLAI++IH+ +IHRD+KPDN FGLC L + + ++ Sbjct: 194 ISETVLAIDAIHQLGFIHRDVKPDNLLLDAKGHVKLSDFGLCTGLKKA-----HRTEFYR 248 Query: 1113 GKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYG 1292 P D + + N T W+KNRR LAYSTVGTPDYIAPEV ++ GY Sbjct: 249 NLTHNPPSDFSFQNMNSKRKAET-------WKKNRRQLAYSTVGTPDYIAPEVFMQTGYN 301 Query: 1293 MECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKL 1472 CDWWSLG IMYEML+G+PPF SE P T RK+++W+ L FP E +S + KDLI + Sbjct: 302 KLCDWWSLGVIMYEMLIGFPPFCSETPQETYRKVMSWKETLAFPPEVPVSEKAKDLILRF 361 Query: 1473 LCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETGAQV 1652 + E R+G G EIK H +F GV W + + AA E+ DT NF+ F E+ Sbjct: 362 CTDSENRIGNGGVEEIKGHPFFEGVDWGHIRERPAAIPIEIRSIDDTSNFDDFPESDILQ 421 Query: 1653 QSSSKAGPWRKMLPSKDANFVGYTYKNFE 1739 + P K SKD F+ YTYK FE Sbjct: 422 PVPNTTEPDYK---SKDWVFLNYTYKRFE 447
>Q6BLJ9:CBK1_DEBHA Serine/threonine-protein kinase CBK1 - Debaryomyces hansenii (Yeast)| (Torulaspora hansenii) Length = 716 Score = 389 bits (999), Expect = e-107 Identities = 214/476 (44%), Positives = 302/476 (63%), Gaps = 26/476 (5%) Frame = +3 Query: 390 PSSATK---QKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQ--NNIL 554 P+S K K ++ K +EN+Y+ + +R +RR LE KL + E + E+ N L Sbjct: 233 PNSLNKIAQDKASSIKLKLENYYQMSVAHAIERNQRRLDLEHKLLNEESGSSEERKNRQL 292 Query: 555 KHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEML 734 ++L KKE++++RL+R K+ +EDF + +IG+GAFGEVRL +++ + +YAMK L KSEM Sbjct: 293 QNLGKKESQFLRLRRTKLSLEDFNTVKVIGKGAFGEVRLVQKRDTGKIYAMKTLLKSEMY 352 Query: 735 RRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTE 914 ++ Q+ HVKAER++LA DS ++V LYYSFQD ++LYLIME+LPGGD+MT+L+R TE Sbjct: 353 KKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQIFTE 412 Query: 915 DEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLC----KPLDSSNF 1082 D +FY+AE VLAIE+IHK +IHRDIKPDN FGL K DS+ + Sbjct: 413 DITRFYMAECVLAIEAIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYY 472 Query: 1083 PNLNE---PDYT-PGKGAKPLP-----DNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYS 1235 L E P +T P G P + S + + + ++Q+ W+K+RR++AYS Sbjct: 473 KKLLEKENPHHTNPQNGNLQAPSMATNNRNSMMVDAIHLTMSNRQQMQTWRKSRRLMAYS 532 Query: 1236 TVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHL 1415 TVGTPDYIAPE+ + +GYG ECDWWSLGAIM+E L+G+PPF SE P T RKI+NW+ L Sbjct: 533 TVGTPDYIAPEIFVHQGYGQECDWWSLGAIMFECLIGWPPFCSETPHETYRKILNWQETL 592 Query: 1416 KFPEEAKLSSETKDLISKLLCNVEQRLGT-KGAHEIKAHTWFRGVQWEKLYQMKAAFVPE 1592 + P++ LS E++DLI KLL N E RLG GA E+K H +FRGV W+ + ++ A F+P+ Sbjct: 593 QIPDDIHLSPESEDLIRKLLTNAENRLGRYNGADELKLHPFFRGVDWDTIRKVDAPFIPK 652 Query: 1593 VNGELDTQNFEKFE-ETGAQVQSSSKAGPWRKML------PSKDANFVGYTYKNFE 1739 + DT+ F E E + SKA R + +D F+GYTY F+ Sbjct: 653 LRSITDTRFFPTDELENVPDSPALSKAMEQRDQVLQNGGNVKEDLPFIGYTYSRFD 708
>P31034:CBK1_KLULA Serine/threonine-protein kinase CBK1 - Kluyveromyces lactis (Yeast)| (Candida sphaerica) Length = 718 Score = 387 bits (994), Expect = e-106 Identities = 209/487 (42%), Positives = 293/487 (60%), Gaps = 35/487 (7%) Frame = +3 Query: 384 DAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHL 563 D + T+ K AA K IEN Y++ + +R +RR LE +L + E +N L L Sbjct: 224 DLLTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASL 283 Query: 564 EKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRG 743 KKE++++RL+R ++ ++DF + +IG+GAFGEVRL ++K + +YAMK L KSEM + Sbjct: 284 GKKESQFLRLRRTRLSLDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKD 343 Query: 744 QVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEA 923 Q+ HVKAER++LA DS ++V LYYSFQD ++LYLIME+LPGGD+MT+L+R TED Sbjct: 344 QLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVT 403 Query: 924 KFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLC----KPLDSSNFPNL 1091 +FY+AE +LAIE IHK +IHRDIKPDN FGL K DSS + L Sbjct: 404 RFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYKKL 463 Query: 1092 NEPDYTPGKGAKPLPDNTSRLTNPSAPKR------------------TQQEQLSHWQKNR 1217 + D + + L P P T ++Q+ W+K+R Sbjct: 464 LQEDEAKKQQQQQQQQQQLNLQKPQLPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSR 523 Query: 1218 RMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIV 1397 R++AYSTVGTPDYIAPE+ L +GYG ECDWWSLGAIMYE L+G+PPF SE P T RKI+ Sbjct: 524 RLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIM 583 Query: 1398 NWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTK-GAHEIKAHTWFRGVQWEKLYQMK 1574 N+ L+FP++ +S E +DLI +LL + E RLG GA EIKAH +F GV W + Q++ Sbjct: 584 NFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVE 643 Query: 1575 AAFVPEVNGELDTQNFEKFE-ETGAQVQSSSKAGPWRKML-----------PSKDANFVG 1718 A ++P+++ DT+ F E E + ++A R+ + +D F+G Sbjct: 644 APYIPKLSSVTDTRFFPTDELENVPDSPAMAQAARQREQMMTQQQGVPQSNAKEDLPFIG 703 Query: 1719 YTYKNFE 1739 YTY F+ Sbjct: 704 YTYSRFD 710
>O13310:ORB6_SCHPO Serine/threonine-protein kinase orb6 - Schizosaccharomyces pombe| (Fission yeast) Length = 469 Score = 382 bits (981), Expect = e-105 Identities = 195/451 (43%), Positives = 283/451 (62%), Gaps = 5/451 (1%) Frame = +3 Query: 399 ATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKET 578 +T KV K+YIE++YK + +R +RR LE++L E +N L+ +KE+ Sbjct: 19 STLDKVQKTKKYIEHYYKVAVDHAVERNQRRINLEQRLATERGSEERKNRQLRASGEKES 78 Query: 579 EYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHV 758 +++R +R ++ +EDF + +IG+GAFGEVRL ++ + +YAMK L K+EM +R Q+ HV Sbjct: 79 QFLRFRRTRLSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHV 138 Query: 759 KAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIA 938 KAER+LL E DS ++V LYY+FQD +LYLIME+LPGGD+MT+L+ DT +ED +FY+A Sbjct: 139 KAERDLLVESDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMA 198 Query: 939 ETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGK 1118 E VLAI +H+ YIHRDIKPDN FGL S+ F ++ Sbjct: 199 ECVLAIADVHRMGYIHRDIKPDNILIDRDGHIKLSDFGL-----STGFYKQDQ----SAS 249 Query: 1119 GAKPLPDNT---SRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGY 1289 KP NT ++ + + +++++ W+KNRR++AYSTVGTPDYIAPE+ L++GY Sbjct: 250 YMKPRTGNTVKRGQMVDAIWLTMSSKDKMATWKKNRRVMAYSTVGTPDYIAPEIFLQQGY 309 Query: 1290 GMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISK 1469 G +CDWWSLGAIM+E L+G+PPF SE+ T RKI+NWR L FP + LS E +DL+ + Sbjct: 310 GQDCDWWSLGAIMFECLIGWPPFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLMDR 369 Query: 1470 LLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNF--EKFEETG 1643 L+ + E RLG GA EI H +F G+ W+ + + A F+P + DT F ++ E+ Sbjct: 370 LMTDSEHRLGRGGAIEIMQHPFFTGIDWDHIRETAAPFIPNLKSITDTHYFPVDELEQVP 429 Query: 1644 AQVQSSSKAGPWRKMLPSKDANFVGYTYKNF 1736 Q + A + L + F+GYTYK F Sbjct: 430 EQPVTQQPASVDPQTLEQTNLAFLGYTYKKF 460
>P38679:COT1_NEUCR Serine/threonine-protein kinase cot-1 - Neurospora crassa| Length = 598 Score = 371 bits (952), Expect = e-102 Identities = 196/472 (41%), Positives = 293/472 (62%), Gaps = 13/472 (2%) Frame = +3 Query: 363 PGKPPVDDAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQ 542 P + P P++ QK + Q + +K +K ++R +R+ +E+KL + A + Sbjct: 131 PERNPDKYGPNANNNQKKCS--QLASDFFKDSVKRARERNQRQSEMEQKLGETN-DARRR 187 Query: 543 NNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKK 722 +I +KE +Y+R R K E+++ + IIG+GAFGEV+L ++K VYAMK L K Sbjct: 188 ESIWSTAGRKEGQYLRFLRTKDKPENYQTIKIIGKGAFGEVKLVQKKADGKVYAMKSLIK 247 Query: 723 SEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKD 902 +EM ++ Q+ HV+AER++LAE DS ++VKLY +FQD FLY++ME+LPGGD+MT+L++ + Sbjct: 248 TEMFKKDQLAHVRAERDILAESDSPWVVKLYTTFQDANFLYMLMEFLPGGDLMTMLIKYE 307 Query: 903 TLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNF 1082 +ED +FYIAE VLAI+++HK +IHRDIKPDN FGL S+ F Sbjct: 308 IFSEDITRFYIAEIVLAIDAVHKLGFIHRDIKPDNILLDRGGHVKLTDFGL-----STGF 362 Query: 1083 PNLNEPDY----TPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTP 1250 L++ +Y GK KP + S + + + Q++ W+++RR++AYSTVGTP Sbjct: 363 HKLHDNNYYTQLLQGKSNKPRDNRNSVAIDQINLTVSNRAQINDWRRSRRLMAYSTVGTP 422 Query: 1251 DYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEE 1430 DYIAPE+ GY +CDWWSLG IM+E LVG+PPF +ED T RKIVNWR L FP++ Sbjct: 423 DYIAPEIFTGHGYSFDCDWWSLGTIMFECLVGWPPFCAEDSHDTYRKIVNWRHSLYFPDD 482 Query: 1431 AKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELD 1610 L + ++LI L+CN E RLG GAHEIK+H +FRGV+++ L +++A F P + +D Sbjct: 483 ITLGVDAENLIRSLICNTENRLGRGGAHEIKSHAFFRGVEFDSLRRIRAPFEPRLTSAID 542 Query: 1611 TQNF--EKFEETG------AQVQSSSKAGP-WRKMLPSKDANFVGYTYKNFE 1739 T F ++ ++T AQ + A P ++ P F+GYT+K F+ Sbjct: 543 TTYFPTDEIDQTDNATLLKAQQAARGAAAPAQQEESPELSLPFIGYTFKRFD 594
>Q9NRM7:LATS2_HUMAN Serine/threonine-protein kinase LATS2 - Homo sapiens (Human)| Length = 1088 Score = 334 bits (857), Expect = 8e-91 Identities = 186/471 (39%), Positives = 273/471 (57%), Gaps = 13/471 (2%) Frame = +3 Query: 264 CEHTMDSARSWFQKFQPRDKSKSPAVPASHGKDPGK---PPVDDAPSSATKQKVA----- 419 C S R+ + + DKS+ A GKD + PV +S ++K Sbjct: 537 CAGMEQSLRAGPNEPEGGDKSRKSAKGDKGGKDKKQIQTSPVPVRKNSRDEEKRESRIKS 596 Query: 420 ----AAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYM 587 A K ++E H + +K+ Q + RR LE+++ A + EQ + K L +KE+ Y Sbjct: 597 YSPYAFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYN 656 Query: 588 RLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAE 767 RL+R KM F + +G GAFGEV L + + ++YAMK L+K ++L R QV HVKAE Sbjct: 657 RLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKAE 716 Query: 768 RNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETV 947 R++LAE D+ ++VKLYYSFQD + LY +M+Y+PGGDMM+LL+R + E A+FYIAE Sbjct: 717 RDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELT 776 Query: 948 LAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAK 1127 LAIES+HK +IHRDIKPDN FGLC ++ + + + Sbjct: 777 LAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSM 836 Query: 1128 PLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDW 1307 D ++N R + + ++++R LA+S VGTP+YIAPEVLL+KGY CDW Sbjct: 837 EPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDW 896 Query: 1308 WSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVE 1487 WS+G I++EMLVG PPF + P T K++NW + L P + KLS E +DLI+KL C+ + Sbjct: 897 WSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSAD 956 Query: 1488 QRLGTKGAHEIKAHTWFRGVQWEK-LYQMKAAFVPEVNGELDTQNFEKFEE 1637 RLG GA ++KAH +F + + + + A +VP ++ +DT NF+ +E Sbjct: 957 HRLGRNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDE 1007
>Q7TSJ6:LATS2_MOUSE Serine/threonine-protein kinase LATS2 - Mus musculus (Mouse)| Length = 1042 Score = 333 bits (855), Expect = 1e-90 Identities = 178/445 (40%), Positives = 266/445 (59%), Gaps = 6/445 (1%) Frame = +3 Query: 420 AAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQR 599 A K ++E H + +K+ Q + RR LE+++ A + EQ + K L +KE+ Y RL+R Sbjct: 559 AFKFFMEQHVENVIKTYQQKVSRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKR 618 Query: 600 HKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLL 779 KM F + +G GAFGEV L + + ++YAMK L+K ++L R QV HVKAER++L Sbjct: 619 AKMDKSMFVKIKTLGIGAFGEVCLACKLDTHALYAMKTLRKKDVLNRNQVAHVKAERDIL 678 Query: 780 AEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 AE D+ ++VKLYYSFQD + LY +M+Y+PGGDMM+LL+R + E A+FYIAE LAIE Sbjct: 679 AEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIE 738 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPD 1139 S+HK +IHRDIKPDN FGLC ++ + + + D Sbjct: 739 SVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGNHMRQDSMEPGD 798 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLG 1319 ++N R + + ++++R LA+S VGTP+YIAPEVLL+KGY CDWWS+G Sbjct: 799 LWDDVSNCRCGDRLKTLEQRAQKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVG 858 Query: 1320 AIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLG 1499 I++EMLVG PPF + P T K++NW S L P + +LS+E +DLI+KL C + RLG Sbjct: 859 VILFEMLVGQPPFLAPTPTETQLKVINWESTLHIPTQVRLSAEARDLITKLCCAADCRLG 918 Query: 1500 TKGAHEIKAHTWFRGVQWEK-LYQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGP 1676 GA ++KAH +F + + + + + A +VP ++ +DT NF+ +E ++S ++ Sbjct: 919 RDGADDLKAHPFFNTIDFSRDIRKQPAPYVPTISHPMDTSNFDPVDEESPWHEASGESAK 978 Query: 1677 WRKMLPSKDAN-----FVGYTYKNF 1736 L S + F +T++ F Sbjct: 979 AWDTLASPSSKHPEHAFYEFTFRRF 1003
>O95835:LATS1_HUMAN Serine/threonine-protein kinase LATS1 - Homo sapiens (Human)| Length = 1130 Score = 330 bits (846), Expect = 1e-89 Identities = 186/502 (37%), Positives = 271/502 (53%), Gaps = 16/502 (3%) Frame = +3 Query: 279 DSARSWFQKFQPRDKSKSPAVPASHGKDPGKPPVDDAPSSATKQKVAAAKQYIENHYKTQ 458 D + ++ DK K + K + S A K ++E H + Sbjct: 591 DESEKSYENVDSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENV 650 Query: 459 MKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTI 638 +KS Q R R+ LE ++ + + Q+ + K L +KE+ Y+RL+R KM F + Sbjct: 651 LKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKT 710 Query: 639 IGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYY 818 +G GAFGEV L R+ ++++YA K L+K ++L R QV HVKAER++LAE D+ ++V+LYY Sbjct: 711 LGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYY 770 Query: 819 SFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIK 998 SFQD + LY +M+Y+PGGDMM+LL+R E A+FYIAE A+ES+HK +IHRDIK Sbjct: 771 SFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIK 830 Query: 999 PDNXXXXXXXXXXXXXFGLC---------KPLDSSNFPNLNEPDYTPGKGAKPLPDNTSR 1151 PDN FGLC K S + P + D++ + P Sbjct: 831 PDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFS-NEWGDPSSCRCGD 889 Query: 1152 LTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 1331 P + +Q Q R LA+S VGTP+YIAPEVLL+ GY CDWWS+G I++ Sbjct: 890 RLKPLERRAARQHQ--------RCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILF 941 Query: 1332 EMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGA 1511 EMLVG PPF ++ P+ T K++NW++ L P +AKLS E DLI KL E RLG GA Sbjct: 942 EMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGA 1001 Query: 1512 HEIKAHTWFRGVQWEK-LYQMKAAFVPEVNGELDTQNFEK------FEETGAQVQSSSKA 1670 EIKAH +F+ + + L Q A+++P++ DT NF+ + + + + Sbjct: 1002 DEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTL 1061 Query: 1671 GPWRKMLPSKDANFVGYTYKNF 1736 W K + F +T++ F Sbjct: 1062 NGWYKNGKHPEHAFYEFTFRRF 1083
>Q8BYR2:LATS1_MOUSE Serine/threonine-protein kinase LATS1 - Mus musculus (Mouse)| Length = 1129 Score = 327 bits (839), Expect = 9e-89 Identities = 183/496 (36%), Positives = 276/496 (55%), Gaps = 21/496 (4%) Frame = +3 Query: 312 PRDKSKSPAVPASHGKDPGKPPVDDAPSSATKQKV--------------AAAKQYIENHY 449 P++ + + D K + +P + K K A K ++E H Sbjct: 587 PKEDDSEKSADSGDSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHV 646 Query: 450 KTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFEL 629 + +KS Q R R+ LE ++ + + Q+ + K L +KE+ Y+RL+R KM F Sbjct: 647 ENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVK 706 Query: 630 LTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVK 809 + +G GAFGEV L R+ ++++YA K L+K ++L R QV HVKAER++LAE D+ ++V+ Sbjct: 707 IKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVR 766 Query: 810 LYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHR 989 LYYSFQD + LY +M+Y+PGGDMM+LL+R E+ A+FYIAE A+ES+HK +IHR Sbjct: 767 LYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHR 826 Query: 990 DIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSA 1169 DIKPDN FGLC ++ + P + + + +N Sbjct: 827 DIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSNCRC 886 Query: 1170 PKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGY 1349 R + + ++++R LA+S VGTP+YIAPEVLL+ GY CDWWS+G I+ EMLVG Sbjct: 887 GDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILCEMLVGQ 946 Query: 1350 PPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAH 1529 PPF ++ P+ T K++ W++ L P +AKLS E DLI KL E RLG GA EIKAH Sbjct: 947 PPFLAQTPLETQMKVIIWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAH 1006 Query: 1530 TWFRGVQWEK-LYQMKAAFVPEVNGELDTQNF-----EKFEETGAQVQS-SSKAGPWRKM 1688 +F+ + + L Q A+++P++ DT NF +K G++ ++ S W K Sbjct: 1007 PFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDGSEEENISDTLSGWYKN 1066 Query: 1689 LPSKDANFVGYTYKNF 1736 + F +T++ F Sbjct: 1067 GKHPEHAFYEFTFRRF 1082
>O75116:ROCK2_HUMAN Rho-associated protein kinase 2 - Homo sapiens (Human)| Length = 1388 Score = 274 bits (701), Expect = 9e-73 Identities = 172/516 (33%), Positives = 263/516 (50%), Gaps = 15/516 (2%) Frame = +3 Query: 342 PASHGKDPGKP---PVDDAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKL 512 P GK PG P P D A +S ++ A + + ++SL D L + Sbjct: 4 PPPTGKMPGAPETAPGDGAGASRQRKLEALIR---DPRSPINVESLLDG------LNSLV 54 Query: 513 QDAEVPAEEQN-NILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTS 689 D + PA +N NI L + E +++ +M ED++++ +IGRGAFGEV+L R K S Sbjct: 55 LDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKAS 114 Query: 690 RSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPG 869 + VYAMK L K EM++R ER+++A +S ++V+L+Y+FQDD +LY++MEY+PG Sbjct: 115 QKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPG 174 Query: 870 GDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXF 1049 GD++ L+ D + E AKFY AE VLA+++IH IHRD+KPDN F Sbjct: 175 GDLVNLMSNYD-VPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADF 233 Query: 1050 GLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLA 1229 G C +D + + + Sbjct: 234 GTCMKMDETGMVHCD--------------------------------------------- 248 Query: 1230 YSTVGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIV 1397 + VGTPDYI+PEVL +G YG ECDWWS+G +YEMLVG PFY++ + T KI+ Sbjct: 249 -TAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIM 307 Query: 1398 NWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQ--WEKLYQM 1571 + ++ L FPE+A++S K+LI L + E RLG G EI+ H +F+ Q W+ + + Sbjct: 308 DHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRET 367 Query: 1572 KAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVND 1751 A VPE++ ++D+ NF+ E+ V++ P K F+G+TY ++ Sbjct: 368 AAPVVPELSSDIDSSNFDDIEDDKGDVETF----PIPKAFVGNQLPFIGFTYYRENLLLS 423 Query: 1752 D-----EVAGIAELKKKSSKSKRPTIKTLFESMDED 1844 D E I K + S+ + + TL E + + Sbjct: 424 DSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNE 459
>Q63644:ROCK1_RAT Rho-associated protein kinase 1 - Rattus norvegicus (Rat)| Length = 1369 Score = 273 bits (698), Expect = 2e-72 Identities = 161/460 (35%), Positives = 240/460 (52%), Gaps = 11/460 (2%) Frame = +3 Query: 498 LERKLQDAEVPAEEQN-NILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLC 674 L+ + D + PA +N NI L + + +++ +M ED+E++ +IGRGAFGEV+L Sbjct: 34 LDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLV 93 Query: 675 REKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIM 854 R K++R VYAMK L K EM++R ER+++A +S ++V+L+Y+FQDD +LY++M Sbjct: 94 RHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVM 153 Query: 855 EYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXX 1034 EY+PGGD++ L+ D + E A+FY AE VLA+++IH +IHRD+KPDN Sbjct: 154 EYMPGGDLVNLMSNYD-VPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHL 212 Query: 1035 XXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKN 1214 FG C ++ K Sbjct: 213 KLADFGTCMKMN----------------------------------------------KE 226 Query: 1215 RRMLAYSTVGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGYPPFYSEDPMST 1382 + + VGTPDYI+PEVL +G YG ECDWWS+G +YEMLVG PFY++ + T Sbjct: 227 GMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGT 286 Query: 1383 CRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQ--WE 1556 KI+N ++ L FP++ +S E K+LI L + E RLG G EIK H +F+ Q WE Sbjct: 287 YSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWE 346 Query: 1557 KLYQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY--- 1727 L A VP+++ ++DT NF+ EE + + P K FVG+TY Sbjct: 347 TLRDTVAPVVPDLSSDIDTSNFDDLEED----KGDEETFPIPKAFVGNQLPFVGFTYYSN 402 Query: 1728 -KNFEIVNDDEVAGIAELKKKSSKSKRPTIKTLFESMDED 1844 + N E + + K +S + TI L E + + Sbjct: 403 RRYLPSANPSENRSSSNVDKNVQESLQKTIYKLEEQLHNE 442
>P70335:ROCK1_MOUSE Rho-associated protein kinase 1 - Mus musculus (Mouse)| Length = 1354 Score = 273 bits (697), Expect = 3e-72 Identities = 161/460 (35%), Positives = 240/460 (52%), Gaps = 11/460 (2%) Frame = +3 Query: 498 LERKLQDAEVPAEEQN-NILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLC 674 L+ + D + PA +N NI L + + +++ +M ED+E++ +IGRGAFGEV+L Sbjct: 34 LDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLV 93 Query: 675 REKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIM 854 R K++R VYAMK L K EM++R ER+++A +S ++V+L+Y+FQDD +LY++M Sbjct: 94 RHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVM 153 Query: 855 EYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXX 1034 EY+PGGD++ L+ D + E A+FY AE VLA+++IH +IHRD+KPDN Sbjct: 154 EYMPGGDLVNLMSNYD-VPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHL 212 Query: 1035 XXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKN 1214 FG C ++ K Sbjct: 213 KLADFGTCMKMN----------------------------------------------KE 226 Query: 1215 RRMLAYSTVGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGYPPFYSEDPMST 1382 + + VGTPDYI+PEVL +G YG ECDWWS+G +YEMLVG PFY++ + T Sbjct: 227 GMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGT 286 Query: 1383 CRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQ--WE 1556 KI+N ++ L FP++ +S E K+LI L + E RLG G EIK H +F+ Q WE Sbjct: 287 YSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWE 346 Query: 1557 KLYQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY--- 1727 L A VP+++ ++DT NF+ EE + + P K FVG+TY Sbjct: 347 TLRDTVAPVVPDLSSDIDTSNFDDLEED----KGDEETFPIPKAFVGNQLPFVGFTYYSN 402 Query: 1728 -KNFEIVNDDEVAGIAELKKKSSKSKRPTIKTLFESMDED 1844 + N E + + K +S + TI L E + + Sbjct: 403 RRYLPSANASENRSSSNVDKSLQESLQKTIYKLEEQLHNE 442
>Q13464:ROCK1_HUMAN Rho-associated protein kinase 1 - Homo sapiens (Human)| Length = 1354 Score = 271 bits (693), Expect = 8e-72 Identities = 160/460 (34%), Positives = 240/460 (52%), Gaps = 11/460 (2%) Frame = +3 Query: 498 LERKLQDAEVPAEEQN-NILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLC 674 L+ + D + PA +N NI L + + +++ +M ED+E++ +IGRGAFGEV+L Sbjct: 34 LDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLV 93 Query: 675 REKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIM 854 R K++R VYAMK L K EM++R ER+++A +S ++V+L+Y+FQDD +LY++M Sbjct: 94 RHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVM 153 Query: 855 EYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXX 1034 EY+PGGD++ L+ D + E A+FY AE VLA+++IH +IHRD+KPDN Sbjct: 154 EYMPGGDLVNLMSNYD-VPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHL 212 Query: 1035 XXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKN 1214 FG C ++ K Sbjct: 213 KLADFGTCMKMN----------------------------------------------KE 226 Query: 1215 RRMLAYSTVGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGYPPFYSEDPMST 1382 + + VGTPDYI+PEVL +G YG ECDWWS+G +YEMLVG PFY++ + T Sbjct: 227 GMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGT 286 Query: 1383 CRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQ--WE 1556 KI+N ++ L FP++ +S E K+LI L + E RLG G EIK H +F+ Q WE Sbjct: 287 YSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWE 346 Query: 1557 KLYQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY--- 1727 L A VP+++ ++DT NF+ EE + + P K FVG+TY Sbjct: 347 TLRDTVAPVVPDLSSDIDTSNFDDLEED----KGEEETFPIPKAFVGNQLPFVGFTYYSN 402 Query: 1728 -KNFEIVNDDEVAGIAELKKKSSKSKRPTIKTLFESMDED 1844 + N ++ + K +S + TI L E + + Sbjct: 403 RRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNE 442
>O77819:ROCK1_RABIT Rho-associated protein kinase 1 - Oryctolagus cuniculus (Rabbit)| Length = 1354 Score = 270 bits (691), Expect = 1e-71 Identities = 159/460 (34%), Positives = 241/460 (52%), Gaps = 11/460 (2%) Frame = +3 Query: 498 LERKLQDAEVPAEEQN-NILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLC 674 L+ + D + PA +N NI L + + +++ +M ED+E++ +IGRGAFGEV+L Sbjct: 34 LDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLV 93 Query: 675 REKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIM 854 R K++R VYAMK L K EM++R ER+++A +S ++V+L+Y+FQDD +LY++M Sbjct: 94 RHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVM 153 Query: 855 EYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXX 1034 EY+PGGD++ L+ D + E A+FY AE VLA+++IH +IHRD+KPDN Sbjct: 154 EYMPGGDLVNLMSNYD-VPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHL 212 Query: 1035 XXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKN 1214 FG C ++ K Sbjct: 213 KLADFGTCMKMN----------------------------------------------KE 226 Query: 1215 RRMLAYSTVGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGYPPFYSEDPMST 1382 + + VGTPDYI+PEVL +G YG ECDWWS+G +YEMLVG PFY++ + T Sbjct: 227 GMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGT 286 Query: 1383 CRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQ--WE 1556 KI+N ++ L FP++ +S E K+LI L + E RLG G EIK H +F+ Q WE Sbjct: 287 YSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWE 346 Query: 1557 KLYQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY--- 1727 L A VP+++ ++DT NF+ EE + + P K FVG+TY Sbjct: 347 TLRDTVAPVVPDLSSDIDTSNFDDLEED----KGDEETFPIPKAFVGNQLPFVGFTYYSN 402 Query: 1728 -KNFEIVNDDEVAGIAELKKKSSKSKRPTIKTLFESMDED 1844 + N ++ + + K ++ + TI L E + + Sbjct: 403 RRYLSPANPNDNRTSSNVDKSLQENLQKTIYKLEEQLHNE 442
>Q28021:ROCK2_BOVIN Rho-associated protein kinase 2 - Bos taurus (Bovine)| Length = 1388 Score = 269 bits (687), Expect = 4e-71 Identities = 169/515 (32%), Positives = 263/515 (51%), Gaps = 14/515 (2%) Frame = +3 Query: 342 PASHGKDPGKPPV--DDAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQ 515 P GK PG P D ++ ++K+ A + + ++SL D L + Sbjct: 4 PPPTGKMPGAPEAVSGDGAGASRQRKLEALIR--DPRSPINVESLLDG------LNPLVL 55 Query: 516 DAEVPAEEQN-NILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSR 692 D + PA +N NI L + E +++ +M ED++++ +IGRGAFGEV+L R K S+ Sbjct: 56 DLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQ 115 Query: 693 SVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGG 872 VYAMK L K EM++R ER+++A +S ++V+L+ +FQDD++LY++MEY+PGG Sbjct: 116 KVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDKYLYMVMEYMPGG 175 Query: 873 DMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFG 1052 D++ L+ D + E AKFY AE VLA+++IH IHRD+KPDN FG Sbjct: 176 DLVNLMSNYD-VPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFG 234 Query: 1053 LCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAY 1232 C +D + + + Sbjct: 235 TCMKMDETGMVHCD---------------------------------------------- 248 Query: 1233 STVGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVN 1400 + VGTPDYI+PEVL +G YG ECDWWS+G ++EMLVG PFY++ + T KI++ Sbjct: 249 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMD 308 Query: 1401 WRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQ--WEKLYQMK 1574 ++ L FPE+A++S K+LI L + E RLG G EIK H +F+ Q W+ + + Sbjct: 309 HKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWNWDNIRETA 368 Query: 1575 AAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDD 1754 A VPE++ ++D+ NF+ E+ V++ P K F+G+TY ++ D Sbjct: 369 APVVPELSSDIDSSNFDDIEDDKGDVETF----PIPKAFVGNQLPFIGFTYYRENLLLSD 424 Query: 1755 -----EVAGIAELKKKSSKSKRPTIKTLFESMDED 1844 E I K + S+ + + TL E + + Sbjct: 425 SPSCKENDSIQSRKNEESQEIQKKLYTLEEHLSTE 459
>Q5VT25:MRCKA_HUMAN Serine/threonine-protein kinase MRCK alpha - Homo sapiens (Human)| Length = 1732 Score = 268 bits (686), Expect = 5e-71 Identities = 152/415 (36%), Positives = 224/415 (53%), Gaps = 7/415 (1%) Frame = +3 Query: 528 PAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAM 707 P + NIL++LE + ++++ ++ EDFE+L +IGRGAFGEV + + K + V+AM Sbjct: 46 PLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAM 105 Query: 708 KKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTL 887 K L K EML+R + + ER++L D+ +I L+Y+FQDD LYL+M+Y GGD++TL Sbjct: 106 KILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTL 165 Query: 888 LMR-KDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L + +D L ED A+FY+AE V+AI+S+H+ +Y+HRDIKPDN FG C Sbjct: 166 LSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSC-- 223 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 K + D T + + VG Sbjct: 224 -------------------LKLMEDGT-------------------------VQSSVAVG 239 Query: 1245 TPDYIAPEVLL-----KKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRS 1409 TPDYI+PE+L K YG ECDWWSLG MYEML G PFY+E + T KI+N + Sbjct: 240 TPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKE 299 Query: 1410 HLKFPEE-AKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFV 1586 +FP + +S KDLI +L+C+ E RLG G + K H +F G+ W+ + +A ++ Sbjct: 300 RFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYI 359 Query: 1587 PEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVND 1751 PEV+ DT NF+ ++ S + P FVG+TY + +++D Sbjct: 360 PEVSSPTDTSNFDVDDD--CLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSD 412
>O54874:MRCKA_RAT Serine/threonine-protein kinase MRCK alpha - Rattus norvegicus (Rat)| Length = 1732 Score = 268 bits (685), Expect = 7e-71 Identities = 152/415 (36%), Positives = 224/415 (53%), Gaps = 7/415 (1%) Frame = +3 Query: 528 PAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAM 707 P + NIL++LE + ++++ ++ EDFE+L +IGRGAFGEV + + K + V+AM Sbjct: 46 PLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAM 105 Query: 708 KKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTL 887 K L K EML+R + + ER++L DS +I L+Y+FQDD LYL+M+Y GGD++TL Sbjct: 106 KILNKWEMLKRAETACFREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTL 165 Query: 888 LMR-KDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L + +D L E+ A+FY+AE V+AI+S+H+ +Y+HRDIKPDN FG C Sbjct: 166 LSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSC-- 223 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 K + D T + + VG Sbjct: 224 -------------------LKLMEDGT-------------------------VQSSVAVG 239 Query: 1245 TPDYIAPEVLL-----KKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRS 1409 TPDYI+PE+L K YG ECDWWSLG MYEML G PFY+E + T KI+N + Sbjct: 240 TPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKE 299 Query: 1410 HLKFPEE-AKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFV 1586 +FP + +S KDLI +L+C+ E RLG G + K H +F G+ W+ + +A ++ Sbjct: 300 RFQFPTQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYI 359 Query: 1587 PEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVND 1751 PEV+ DT NF+ ++ S + P FVG+TY + +++D Sbjct: 360 PEVSSPTDTSNFDVDDD--CLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSD 412
>Q3UU96:MRCKA_MOUSE Serine/threonine-protein kinase MRCK alpha - Mus musculus (Mouse)| Length = 1719 Score = 268 bits (685), Expect = 7e-71 Identities = 152/415 (36%), Positives = 224/415 (53%), Gaps = 7/415 (1%) Frame = +3 Query: 528 PAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAM 707 P + NIL++LE + ++++ ++ EDFE+L +IGRGAFGEV + + K + V+AM Sbjct: 46 PLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAM 105 Query: 708 KKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTL 887 K L K EML+R + + ER++L DS +I L+Y+FQDD LYL+M+Y GGD++TL Sbjct: 106 KILNKWEMLKRAETACFREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTL 165 Query: 888 LMR-KDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L + +D L E+ A+FY+AE V+AI+S+H+ +Y+HRDIKPDN FG C Sbjct: 166 LSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSC-- 223 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 K + D T + + VG Sbjct: 224 -------------------LKLMEDGT-------------------------VQSSVAVG 239 Query: 1245 TPDYIAPEVLL-----KKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRS 1409 TPDYI+PE+L K YG ECDWWSLG MYEML G PFY+E + T KI+N + Sbjct: 240 TPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKE 299 Query: 1410 HLKFPEE-AKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFV 1586 +FP + +S KDLI +L+C+ E RLG G + K H +F G+ W+ + +A ++ Sbjct: 300 RFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYI 359 Query: 1587 PEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVND 1751 PEV+ DT NF+ ++ S + P FVG+TY + +++D Sbjct: 360 PEVSSPTDTSNFDVDDD--CLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSD 412
>P70336:ROCK2_MOUSE Rho-associated protein kinase 2 - Mus musculus (Mouse)| Length = 1388 Score = 265 bits (676), Expect = 7e-70 Identities = 160/471 (33%), Positives = 244/471 (51%), Gaps = 9/471 (1%) Frame = +3 Query: 342 PASHGKDPGKPPV--DDAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQ 515 P GK PG P D + ++K+ A + + ++SL D L + Sbjct: 4 PPPTGKMPGAPEAAPGDGAGAGRQRKLEALIR--DPRSPINVESLLDG------LNSLVL 55 Query: 516 DAEVPAEEQN-NILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSR 692 D + PA +N NI L + E +++ +M ED++++ +IGRGAFGEV+L R K S+ Sbjct: 56 DLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQ 115 Query: 693 SVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGG 872 VYAMK L K EM++R ER+++A +S ++V+L+ +FQDD +LY++MEY+PGG Sbjct: 116 KVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGG 175 Query: 873 DMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFG 1052 D++ L+ D + E AKFY AE VLA+++IH IHRD+KPDN FG Sbjct: 176 DLVNLMSNYD-VPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFG 234 Query: 1053 LCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAY 1232 C +D + + + Sbjct: 235 TCMKMDETGMVHCD---------------------------------------------- 248 Query: 1233 STVGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVN 1400 + VGTPDYI+PEVL +G YG ECDWWS+G ++EMLVG PFY++ + T KI++ Sbjct: 249 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMD 308 Query: 1401 WRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQ--WEKLYQMK 1574 ++ L FPE+ ++S K+LI L + E RLG G EIK H +F+ Q W+ + + Sbjct: 309 HKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWNWDNIRETA 368 Query: 1575 AAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY 1727 A VPE++ ++D+ NF+ E+ V++ P K F+G+TY Sbjct: 369 APVVPELSSDIDSSNFDDIEDDKGDVETF----PIPKAFVGNQLPFIGFTY 415
>Q62868:ROCK2_RAT Rho-associated protein kinase 2 - Rattus norvegicus (Rat)| Length = 1379 Score = 260 bits (664), Expect = 2e-68 Identities = 146/411 (35%), Positives = 223/411 (54%), Gaps = 7/411 (1%) Frame = +3 Query: 516 DAEVPAEEQN-NILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSR 692 D + PA +N NI L + E +++ +M ED++++ +IGRGAFGEV+L R K S+ Sbjct: 47 DLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQ 106 Query: 693 SVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGG 872 VYAMK L K EM++R ER+++A +S ++V+L+ +FQDD +LY++MEY+PGG Sbjct: 107 KVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGG 166 Query: 873 DMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFG 1052 D++ L+ D + E AKFY AE VLA+++IH IHRD+KPDN FG Sbjct: 167 DLVNLMSNYD-VPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFG 225 Query: 1053 LCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAY 1232 C +D + + + Sbjct: 226 TCMKMDETGMVHCD---------------------------------------------- 239 Query: 1233 STVGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVN 1400 + VGTPDYI+PEVL +G YG ECDWWS+G ++EMLVG PFY++ + T KI++ Sbjct: 240 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMD 299 Query: 1401 WRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQ--WEKLYQMK 1574 ++ L FPE+ ++S K+LI L + E RLG G EIK+ ++F+ Q W+ + + Sbjct: 300 HKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRNGVEEIKSASFFKNDQWNWDNIRETA 359 Query: 1575 AAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY 1727 A VPE++ ++D+ NF+ E+ V++ P K F+G+TY Sbjct: 360 APVVPELSSDIDSSNFDDIEDDKGDVETF----PIPKAFVGNQLPFIGFTY 406
>Q80UW5:MRCKG_MOUSE Serine/threonine-protein kinase MRCK gamma - Mus musculus (Mouse)| Length = 1551 Score = 260 bits (664), Expect = 2e-68 Identities = 149/413 (36%), Positives = 222/413 (53%), Gaps = 10/413 (2%) Frame = +3 Query: 519 AEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSV 698 + P + N+ + L +++ ++ +DFE+L +IGRGAFGEV + R++ S + Sbjct: 37 SSAPLRRERNVAQFLSWASPFVTKVKELRLQRDDFEILKVIGRGAFGEVAVVRQRGSGQI 96 Query: 699 YAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDM 878 +AMK L K EML+R + + ER++L + DS ++ L+Y+FQD+E+LYL+M+Y GGD+ Sbjct: 97 FAMKMLHKWEMLKRAETACFREERDVLVKGDSRWVTALHYAFQDEEYLYLVMDYYAGGDL 156 Query: 879 MTLLMR-KDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGL 1055 +TLL R +D L + A+FY+AE VLAI S+H+ Y+HRD+KPDN FG Sbjct: 157 LTLLSRFEDRLPPELAQFYLAEMVLAIHSLHQLGYVHRDVKPDNILLDMNGHIRLADFGS 216 Query: 1056 CKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYS 1235 C L N + + + S Sbjct: 217 CLRL------------------------NNNGMVDSSV---------------------- 230 Query: 1236 TVGTPDYIAPEVLL-----KKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVN 1400 VGTPDYI+PE+L K YG +CDWWSLG YE+L G PFY+E + T KI+N Sbjct: 231 AVGTPDYISPEILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMN 290 Query: 1401 WRSHLKFPEE-AKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKA 1577 HL+FP + + + +DLI +LLC E+RLG G + + H +F GV WE+L A Sbjct: 291 HEDHLQFPADVTDVPASAQDLIRQLLCRQEERLGRGGLDDFRKHPFFEGVDWERLATSTA 350 Query: 1578 AFVPEVNGELDTQNFEKFEETGAQVQS---SSKAGPWRKMLPSKDANFVGYTY 1727 ++PE+ G +DT NF+ ++T + ++ SS LP FVG+TY Sbjct: 351 PYIPELRGPMDTSNFDVDDDTLNRPETLPPSSHGAFSGHHLP-----FVGFTY 398
>Q6DT37:MRCKG_HUMAN Serine/threonine-protein kinase MRCK gamma - Homo sapiens (Human)| Length = 1551 Score = 259 bits (662), Expect = 3e-68 Identities = 150/408 (36%), Positives = 218/408 (53%), Gaps = 7/408 (1%) Frame = +3 Query: 585 MRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKA 764 +RLQR +DFE+L +IGRGAFGEV + R++ + ++AMK L K EML+R + + Sbjct: 64 LRLQR-----DDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFRE 118 Query: 765 ERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMR-KDTLTEDEAKFYIAE 941 ER++L + DS ++ L+Y+FQD+E+LYL+M+Y GGD++TLL R +D L + A+FY+AE Sbjct: 119 ERDVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAE 178 Query: 942 TVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKG 1121 VLAI S+H+ Y+HRD+KPDN FG C L Sbjct: 179 MVLAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRL------------------ 220 Query: 1122 AKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLL-----KKG 1286 NT+ + + S VGTPDYI+PE+L K Sbjct: 221 ------NTNGMVDSSV----------------------AVGTPDYISPEILQAMEEGKGH 252 Query: 1287 YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEA-KLSSETKDLI 1463 YG +CDWWSLG YE+L G PFY+E + T KI+N HL+FP + + + +DLI Sbjct: 253 YGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPDVPDVPASAQDLI 312 Query: 1464 SKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETG 1643 +LLC E+RLG G + + H +F GV WE+L A ++PE+ G +DT NF+ ++T Sbjct: 313 RQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPMDTSNFDVDDDT- 371 Query: 1644 AQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAELKKK 1787 + P FVG+TY + + A L++K Sbjct: 372 -LNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERK 418
>Q7TT49:MRCKB_RAT Serine/threonine-protein kinase MRCK beta - Rattus norvegicus (Rat)| Length = 1713 Score = 257 bits (657), Expect = 1e-67 Identities = 157/441 (35%), Positives = 230/441 (52%), Gaps = 12/441 (2%) Frame = +3 Query: 591 LQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAER 770 +Q H+ EDFE++ +IGRGAFGEV + + K + +YAMK L K EML+R + + ER Sbjct: 69 MQLHR---EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREER 125 Query: 771 NLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMR-KDTLTEDEAKFYIAETV 947 ++L D +I L+Y+FQD+ +LYL+M+Y GGD++TLL + +D L ED A+FYI E V Sbjct: 126 DVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMV 185 Query: 948 LAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAK 1127 LAI+SIH+ +Y+HRDIKPDN FG C ++ Sbjct: 186 LAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDG---------------- 229 Query: 1128 PLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVL--LKKG---YG 1292 T Q ++ VGTPDYI+PE+L ++ G YG Sbjct: 230 -----------------TVQSSVA-------------VGTPDYISPEILQAMEDGMGKYG 259 Query: 1293 MECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEE-AKLSSETKDLISK 1469 ECDWWSLG MYEML G PFY+E + T KI+N +FP +S E KDLI + Sbjct: 260 PECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQR 319 Query: 1470 LLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETGAQ 1649 L+C+ E+RLG G + K H +F G+ WE + ++A ++P+V+ DT NF+ ++ Sbjct: 320 LICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRN 379 Query: 1650 VQ---SSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAELKKKSSKSKRPTIKT 1820 ++ S G LP F+G+T+ +S S R ++K+ Sbjct: 380 IEILPPGSHTGFSGLHLP-----FIGFTFTT-----------------ESCFSDRGSLKS 417 Query: 1821 LFES--MDEDEPVHGSFLNML 1877 + +S + +DE V N L Sbjct: 418 MIQSNTLTKDEDVQRDLENSL 438
>Q7TT50:MRCKB_MOUSE Serine/threonine-protein kinase MRCK beta - Mus musculus (Mouse)| Length = 1713 Score = 255 bits (652), Expect = 4e-67 Identities = 147/397 (37%), Positives = 214/397 (53%), Gaps = 10/397 (2%) Frame = +3 Query: 591 LQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAER 770 +Q H+ EDFE++ +IGRGAFGEV + + + + +YAMK L K EML+R + + ER Sbjct: 69 MQLHR---EDFEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREER 125 Query: 771 NLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMR-KDTLTEDEAKFYIAETV 947 ++L D +I L+Y+FQD+ +LYL+M+Y GGD++TLL + +D L ED A+FYI E V Sbjct: 126 DVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMV 185 Query: 948 LAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAK 1127 LAI+SIH+ +Y+HRDIKPDN FG C ++ Sbjct: 186 LAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDG---------------- 229 Query: 1128 PLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVL--LKKG---YG 1292 T Q ++ VGTPDYI+PE+L ++ G YG Sbjct: 230 -----------------TVQSSVA-------------VGTPDYISPEILQAMEDGMGKYG 259 Query: 1293 MECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEE-AKLSSETKDLISK 1469 ECDWWSLG MYEML G PFY+E + T KI+N +FP +S E KDLI + Sbjct: 260 PECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQR 319 Query: 1470 LLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETGAQ 1649 L+C+ E+RLG G + K H +F G+ WE + ++A ++P+V+ DT NF+ ++ Sbjct: 320 LICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDMLRN 379 Query: 1650 VQ---SSSKAGPWRKMLPSKDANFVGYTYKNFEIVND 1751 ++ S G LP F+G+T+ +D Sbjct: 380 IEILPPGSHTGFSGLHLP-----FIGFTFTTESCFSD 411
>Q9Y5S2:MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta - Homo sapiens (Human)| Length = 1711 Score = 254 bits (650), Expect = 8e-67 Identities = 140/352 (39%), Positives = 197/352 (55%), Gaps = 7/352 (1%) Frame = +3 Query: 591 LQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAER 770 +Q H+ EDFE++ +IGRGAFGEV + + K + +YAMK L K EML+R + + ER Sbjct: 69 MQLHR---EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREER 125 Query: 771 NLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMR-KDTLTEDEAKFYIAETV 947 ++L D +I L+Y+FQD+ LYL+M+Y GGD++TLL + +D L ED A+FYI E V Sbjct: 126 DVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMV 185 Query: 948 LAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAK 1127 LAI+SIH+ +Y+HRDIKPDN FG C ++ Sbjct: 186 LAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDG---------------- 229 Query: 1128 PLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVL--LKKG---YG 1292 T Q ++ VGTPDYI+PE+L ++ G YG Sbjct: 230 -----------------TVQSSVA-------------VGTPDYISPEILQAMEDGMGKYG 259 Query: 1293 MECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEE-AKLSSETKDLISK 1469 ECDWWSLG MYEML G PFY+E + T KI+N +FP +S E KDLI + Sbjct: 260 PECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQR 319 Query: 1470 LLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFE 1625 L+C+ E+RLG G + K H +F G+ WE + ++A ++P+V+ DT NF+ Sbjct: 320 LICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFD 371
>Q09013:DMPK_HUMAN Myotonin-protein kinase - Homo sapiens (Human)| Length = 639 Score = 244 bits (622), Expect = 1e-63 Identities = 147/428 (34%), Positives = 219/428 (51%), Gaps = 17/428 (3%) Frame = +3 Query: 585 MRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKA 764 +RL+ ++ +DFE+L +IGRGAF EV + + K + VYAMK + K +ML+RG+V + Sbjct: 69 VRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFRE 128 Query: 765 ERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMR-KDTLTEDEAKFYIAE 941 ER++L D +I +L+++FQD+ +LYL+MEY GGD++TLL + + + + A+FY+AE Sbjct: 129 ERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAE 188 Query: 942 TVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKG 1121 V+AI+S+H+ Y+HRDIKPDN FG C L + Sbjct: 189 IVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRA---------------- 232 Query: 1122 AKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKG----- 1286 D T R + VGTPDY++PE+L G Sbjct: 233 -----DGTVR-------------------------SLVAVGTPDYLSPEILQAVGGGPGT 262 Query: 1287 --YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP-EEAKLSSETKD 1457 YG ECDWW+LG YEM G PFY++ T KIV+++ HL P + + E +D Sbjct: 263 GSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARD 322 Query: 1458 LISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEE 1637 I +LLC E RLG GA + + H +F G+ W+ L F P+ G DT NF+ E+ Sbjct: 323 FIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFDLVED 382 Query: 1638 -------TGAQVQSSSKAG-PWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAELKKKSS 1793 G + S + G P LP FVGY+Y + D EV G ++ ++ Sbjct: 383 GLTAMVSGGGETLSDIREGAPLGVHLP-----FVGYSYSCMAL-RDSEVPGPTPMEVEAE 436 Query: 1794 KSKRPTIK 1817 + P ++ Sbjct: 437 QLLEPHVQ 444
>P54265:DMPK_MOUSE Myotonin-protein kinase - Mus musculus (Mouse)| Length = 631 Score = 241 bits (616), Expect = 7e-63 Identities = 143/397 (36%), Positives = 203/397 (51%), Gaps = 17/397 (4%) Frame = +3 Query: 588 RLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAE 767 RL+ ++ +DFE+L +IGRGAF EV + + K + VYAMK + K +ML+RG+V + E Sbjct: 60 RLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREE 119 Query: 768 RNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMR-KDTLTEDEAKFYIAET 944 R++L + D +I +L+++FQD+ +LYL+MEY GGD++TLL + + + + A+FY+AE Sbjct: 120 RDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEI 179 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 V+AI+S+H+ Y+HRDIKPDN FG C L Sbjct: 180 VMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLQ------------------ 221 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKG------ 1286 PD R + VGTPDY++PE+L G Sbjct: 222 ---PDGMVR-------------------------SLVAVGTPDYLSPEILQAVGGGPGAG 253 Query: 1287 -YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP-EEAKLSSETKDL 1460 YG ECDWW+LG YEM G PFY++ T KIV++R HL P + + E +DL Sbjct: 254 SYGPECDWWALGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPLADTVVPEEAQDL 313 Query: 1461 ISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEET 1640 I LLC E RLG GA + + H +F G+ WE L F P+ G DT NF+ E+ Sbjct: 314 IRGLLCPAEIRLGRGGAGDFQKHPFFFGLDWEGLRDSVPPFTPDFEGATDTCNFDVVEDR 373 Query: 1641 --------GAQVQSSSKAGPWRKMLPSKDANFVGYTY 1727 G + + P LP FVGY+Y Sbjct: 374 LTAMVSGGGETLSDMQEDMPLGVRLP-----FVGYSY 405
>O14578:CTRO_HUMAN Citron Rho-interacting kinase - Homo sapiens (Human)| Length = 2027 Score = 236 bits (603), Expect = 2e-61 Identities = 149/449 (33%), Positives = 223/449 (49%), Gaps = 14/449 (3%) Frame = +3 Query: 552 LKHLEKKETEYM----RLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLK 719 +KH+ +Y LQ + +DFE+ +++G G F EV++ REK + +YAMK +K Sbjct: 70 IKHVSNFVRKYSDTIAELQELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMK 129 Query: 720 KSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMR- 896 K +L + QV + ERN+L+ S +I +L Y+FQD LYL+MEY PGGD+++LL R Sbjct: 130 KKALLAQEQVSFFEEERNILSRSTSPWIPQLQYAFQDKNHLYLVMEYQPGGDLLSLLNRY 189 Query: 897 KDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSS 1076 +D L E+ +FY+AE +LA+ S+H Y+HRDIKP+N FG ++S+ Sbjct: 190 EDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILVDRTGHIKLVDFGSAAKMNSN 249 Query: 1077 NFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDY 1256 N P +GTPDY Sbjct: 250 KMVNAKLP----------------------------------------------IGTPDY 263 Query: 1257 IAPEVLL------KKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLK 1418 +APEVL K YG++CDWWS+G I YEM+ G PF T I+N++ LK Sbjct: 264 MAPEVLTVMNGDGKGTYGLDCDWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLK 323 Query: 1419 FPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVN 1598 FP++ K+SS+ DLI LLC ++RL +G + H +F + W + FVP + Sbjct: 324 FPDDPKVSSDFLDLIQSLLCGQKERLKFEG---LCCHPFFSKIDWNNIRNSPPPFVPTLK 380 Query: 1599 GELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY-KNFEIVNDDE--VAGI 1769 + DT NF++ E+ S + P ++ FVG++Y K I+ E V+G+ Sbjct: 381 SDDDTSNFDEPEKNSWVSSSPCQLSP--SGFSGEELPFVGFSYSKALGILGRSESVVSGL 438 Query: 1770 AELKKKSSKSKRPTIKTLFESMDEDEPVH 1856 K SS K+ IK+ E D + H Sbjct: 439 DSPAKTSSMEKKLLIKSK-ELQDSQDKCH 466
>O94487:PPK35_SCHPO Serine/threonine-protein kinase ppk35 - Schizosaccharomyces pombe| (Fission yeast) Length = 624 Score = 228 bits (581), Expect = 8e-59 Identities = 144/467 (30%), Positives = 234/467 (50%), Gaps = 24/467 (5%) Frame = +3 Query: 402 TKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETE 581 T++K A + + N+Y + ++ + RKER + E + + +Q + K +E Sbjct: 91 TRRKRMACQVFFLNYYISTIEYHKLRKER--LEEFTACTSSLKQSKQKRLWKEHCGRERA 148 Query: 582 YMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVK 761 ++R +R K+ F+LL +G+G +G V L +++ + + AMK +KKS + + +V+H+ Sbjct: 149 FLRKKRTKIQCSHFDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHIL 208 Query: 762 AERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAE 941 ER++L +S ++VKLYY+FQD E +YL MEY+PGGD T L K L E++ +FY+AE Sbjct: 209 NERDILTNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAE 268 Query: 942 TVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKG 1121 V AI ++HK Y+HRD+KP+N FGL + +SN N Sbjct: 269 MVAAISAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSNQVN----------- 317 Query: 1122 AKPLPDNTSRLTNPSAPKRTQQEQLSHW----QKNRRMLAYSTVGTPDYIAPEVLLKKGY 1289 L NP P TQ+++ + + +KN + S VG+P+Y+APEV+ K Y Sbjct: 318 --RLQHALVSAVNPQRPYLTQKQRRNIYKALLEKNENKV-NSVVGSPEYMAPEVVYGKKY 374 Query: 1290 GMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEE----------AKL 1439 D+WSLG I YE LVGYPPF T + WR L+ P + + Sbjct: 375 DRTVDYWSLGCICYECLVGYPPFSGSTLQETWTNLYYWREMLQRPSKNENGIYDKKARSV 434 Query: 1440 SSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKA-AFVPEVNGELDTQ 1616 S E I+K L R + EI+ H +F+ + W L + FVP + +LDT Sbjct: 435 SDEAWSFITKCLTEPTSRF--QSTIEIQKHPFFKRLHWNGLRKRAVPPFVPRLENQLDTS 492 Query: 1617 NFEKF---------EETGAQVQSSSKAGPWRKMLPSKDANFVGYTYK 1730 F+ F ++ + + + + ++ F+G+T+K Sbjct: 493 YFDDFNDEQVLDAYKDVYEKQRKAEQKAKSNGVMNGNQRQFLGFTFK 539
>P49025:CTRO_MOUSE Citron Rho-interacting kinase - Mus musculus (Mouse)| Length = 2055 Score = 223 bits (569), Expect = 2e-57 Identities = 141/450 (31%), Positives = 221/450 (49%), Gaps = 10/450 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKL 716 + ++ ++K L+ + DFE+ +++G G F EV++ REK + VYAMK + Sbjct: 69 KMKHVSSFVQKYSDTIAELRELQPSARDFEVRSLVGCGHFAEVQVVREKATGDVYAMKIM 128 Query: 717 KKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMR 896 KK +L + QV + ERN+L+ S +I +L Y+FQD LYL+MEY PGGD ++LL R Sbjct: 129 KKKALLAQEQVSFFEEERNILSRSTSPWIPQLQYAFQDKNNLYLVMEYQPGGDFLSLLNR 188 Query: 897 -KDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDS 1073 +D L E +FY+AE +LA+ S+H+ Y+HRDIKP+N FG ++S Sbjct: 189 YEDQLDESMIQFYLAELILAVHSVHQMGYVHRDIKPENILIDRTGEIKLVDFGSAAKMNS 248 Query: 1074 SNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPD 1253 + ++ A +GTPD Sbjct: 249 N-----------------------------------------------KVDAKLPIGTPD 261 Query: 1254 YIAPEVLL-----KKG-YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHL 1415 Y+APEVL ++G YG++CDWWS+G + YEM+ G PF T I+N++ L Sbjct: 262 YMAPEVLTVMNEDRRGTYGLDCDWWSVGVVAYEMVYGKTPFTEGTSARTFNNIMNFQRFL 321 Query: 1416 KFPEEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEV 1595 KFP++ K+SSE DL+ LLC ++RL +G + H +F W + FVP + Sbjct: 322 KFPDDPKVSSELLDLLQSLLCVQKERLKFEG---LCCHPFFARTDWNNIRNSPPPFVPTL 378 Query: 1596 NGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYK---NFEIVNDDEVAG 1766 + DT NF++ E+ S + P ++ FVG++Y + ++ V+ Sbjct: 379 KSDDDTSNFDEPEKNSWVSSSVCQLSP--SGFSGEELPFVGFSYSKALGYLGRSESVVSS 436 Query: 1767 IAELKKKSSKSKRPTIKTLFESMDEDEPVH 1856 + K SS K+ IK+ E D + H Sbjct: 437 LDSPAKVSSMEKKLLIKSK-ELQDSQDKCH 465
>Q09898:SID2_SCHPO Serine/threonine-protein kinase sid2 - Schizosaccharomyces pombe| (Fission yeast) Length = 607 Score = 222 bits (566), Expect = 4e-57 Identities = 133/464 (28%), Positives = 231/464 (49%), Gaps = 21/464 (4%) Frame = +3 Query: 405 KQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEY 584 K+ + + +HY Q+ L RK+R + E +L + P ++ ++K +E Y Sbjct: 138 KRMATICQMFFLDHYFEQLHYLYTRKQRARLFEEQL--LKEPDSRRDELVKRYNGRERVY 195 Query: 585 MRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKA 764 +R +R ++ DF+ +T +G+G +G V L R++ ++ + A+K + KS + + ++ HV Sbjct: 196 LRKRRTRISHGDFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDEIRHVLT 255 Query: 765 ERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 ER++L +S ++V+L Y+FQD +YL ME++PGGD TLL L + AKFY E Sbjct: 256 ERDILTTANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFYATEM 315 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 LAI+++H+ YIHRD+KP+N FGL + S K Sbjct: 316 FLAIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSSGIISK-------------KKI 362 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQ---KNRRMLAYSTVGTPDYIAPEVLLKKGYGM 1295 + + + N P+R+ +E+ ++ + A+S VG+PDY+APEVL + Y Sbjct: 363 ESMKIRLQEVNNVVVPERSMRERRQVFRTLLSQDPVYAHSVVGSPDYMAPEVLRGENYNH 422 Query: 1296 ECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE-------EAKLSSETK 1454 D+WSLG IMYE L G+PPF + T + NWR + P E + Sbjct: 423 SVDYWSLGCIMYECLSGFPPFSGSNVNETWSNLKNWRKCFQRPHYDDPRDLEFNWRDDAW 482 Query: 1455 DLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKL-YQMKAAFVPEVNGELDTQNFEKF 1631 D + + + + R + ++ H +F + W+ + + FVP++N E+D F+ F Sbjct: 483 DFVCHCITDPKDRFCS--LKQVMQHPYFSKIDWKNVRTAYRPPFVPDLNSEIDAGYFDDF 540 Query: 1632 ----------EETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKN 1733 E Q ++ + K P ++A F+G+T+++ Sbjct: 541 TNENDMSKYKEVHEKQAAIANMVNTFNK--PKRNA-FIGFTFRH 581
>O15021:MAST4_HUMAN Microtubule-associated serine/threonine-protein kinase 4 - Homo| sapiens (Human) Length = 2444 Score = 218 bits (556), Expect = 6e-56 Identities = 124/350 (35%), Positives = 183/350 (52%), Gaps = 3/350 (0%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 R K DFE + +I GA+G V R K SR +AMKK+ K ++ R Q++ ER++ Sbjct: 383 RRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDI 442 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ ++V +Y SF+ L ++MEY+ GGD TL+ L D A+ Y AETVLA+ Sbjct: 443 LTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLAL 502 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLP 1136 E +H + +HRD+KPDN FGL K S NL E Sbjct: 503 EYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYE------------- 549 Query: 1137 DNTSRLTNPSAPKRTQQEQLSHWQKN-RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 H +K+ R L GTP+YIAPEV+L++GYG DWW+ Sbjct: 550 --------------------GHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWA 589 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKL-SSETKDLISKLL-CNVE 1487 +G I+YE LVG PF+ + P ++++ + +PE+ + + +DLI+ LL N Sbjct: 590 MGIILYEFLVGCVPFFGDTPEELFGQVIS--DEINWPEKDEAPPPDAQDLITLLLRQNPL 647 Query: 1488 QRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEE 1637 +RLGT GA+E+K H +FR + W L + KA F+P++ E DT F+ E Sbjct: 648 ERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSE 697
>P05131:KAPB1_BOVIN cAMP-dependent protein kinase, beta-1-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 218 bits (555), Expect = 8e-56 Identities = 125/388 (32%), Positives = 198/388 (51%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRLQRH----KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 E ++ + L K + ++++ + G+EDFE +G G+FG V L + K + YA Sbjct: 12 EVESVKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++V+L Y+F+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + K R ++ G Sbjct: 192 V-----------------------------------------------KGR---TWTLCG 201 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TP+Y+APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G +IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFRGSGDTSNFDDYEEEDIRVSITEKCG 345
>Q60592:MAST2_MOUSE Microtubule-associated serine/threonine-protein kinase 2 - Mus| musculus (Mouse) Length = 1734 Score = 218 bits (554), Expect = 1e-55 Identities = 125/354 (35%), Positives = 185/354 (52%), Gaps = 3/354 (0%) Frame = +3 Query: 615 EDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS 794 EDFE + +I GA+G V L R K++R +AMKK+ K ++ R Q++ ER++L ++ Sbjct: 451 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 510 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V ++ SF+ L ++MEY+ GGD TLL L D + Y AETVLA+E +H + Sbjct: 511 PFVVSMFCSFETKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 570 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 +HRD+KPDN FGL K S NL E Sbjct: 571 GIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYE------------------- 611 Query: 1155 TNPSAPKRTQQEQLSHWQKN-RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 1331 H +K+ R L GTP+YIAPEV+L++GYG DWW++G I+Y Sbjct: 612 --------------GHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILY 657 Query: 1332 EMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE-EAKLSSETKDLISKLL-CNVEQRLGTK 1505 E LVG PF+ + P ++++ + +PE + L + +DL SKLL N +RLGT Sbjct: 658 EFLVGCVPFFGDTPEELFGQVIS--DEIVWPEGDDALPPDAQDLTSKLLHQNPLERLGTS 715 Query: 1506 GAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSK 1667 A+E+K H +F G+ W L + KA F+P++ E DT F+ E V S + Sbjct: 716 SAYEVKQHPFFMGLDWTGLLRQKAEFIPQLESEDDTSYFDTRSERYHHVDSEDE 769
>P05383:KAPCB_PIG cAMP-dependent protein kinase, beta-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 218 bits (554), Expect = 1e-55 Identities = 125/388 (32%), Positives = 198/388 (51%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRLQRH----KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 E ++ + L K + ++++ + G+EDFE +G G+FG V L + K + YA Sbjct: 12 EVESVKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++V+L +SF+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEFSFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + K R ++ G Sbjct: 192 V-----------------------------------------------KGR---TWTLCG 201 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TP+Y+APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G +IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFRGSGDTSNFDDYEEEDIRVSITEKCG 345
>P24256:KAPB2_BOVIN cAMP-dependent protein kinase, beta-2-catalytic subunit - Bos taurus| (Bovine) Length = 397 Score = 217 bits (553), Expect = 1e-55 Identities = 122/360 (33%), Positives = 186/360 (51%), Gaps = 5/360 (1%) Frame = +3 Query: 609 GVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 G+EDFE +G G+FG V L + K + YAMK L K ++++ Q+EH E+ +L V Sbjct: 86 GLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV 145 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 + ++V+L Y+F+D+ LY++MEY+PGG+M + L R +E A+FY A+ VL E +H Sbjct: 146 NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 205 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 + I+RD+KP+N FG K + Sbjct: 206 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--------------------------- 238 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 K R ++ GTP+Y+APE++L KGY DWW+LG ++ Sbjct: 239 --------------------KGR---TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLI 275 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT- 1502 YEM GYPPF+++ P+ KIV+ + ++FP + SS+ KDL+ LL ++ +R G Sbjct: 276 YEMAAGYPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNL 331 Query: 1503 -KGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKFEETGAQVQSSSKAG 1673 G +IK H WF W +YQ K A F+P+ G DT NF+ +EE +V + K G Sbjct: 332 KNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCG 391
>P0C1B1:CBK1_EMENI Serine/threonine-protein kinase cbk1 - Emericella nidulans| (Aspergillus nidulans) Length = 884 Score = 217 bits (553), Expect = 1e-55 Identities = 159/526 (30%), Positives = 235/526 (44%), Gaps = 100/526 (19%) Frame = +3 Query: 387 APSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLE 566 +P+ T + A K ++E H+ T + L R +RR L++ ++ + EE + KH Sbjct: 269 SPTIQTTEATAIVKVFLETHFHTLLSGLDARTQRRLELDQYIETFPLSPEEVVRVRKHWV 328 Query: 567 KKETEYMRLQR-------------HKMGVEDFELLTIIGRGAFGEVRLCREKTS------ 689 +E +Y+R R + FE L I+GRG+FG VRL REK + Sbjct: 329 TQERDYLRQYRVLKSRPQDKTSRAGTASLAGFEPLKILGRGSFGVVRLVREKRTDEQTQS 388 Query: 690 -------------------RSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDSAYIVK 809 + V+AMK ++KS M+R Q H++AER+ L+A S ++V Sbjct: 389 GRVPLAPKTNHRQAMTGVKKDVFAMKVIRKSVMIRNCQEAHLRAERDFLVASAKSRWVVP 448 Query: 810 LYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHR 989 L SFQD + LYL+M+Y+ GGD + LL+R + L E A++Y+AE +L IE H+ IHR Sbjct: 449 LIASFQDQKHLYLVMDYMVGGDFLGLLIRHNILRESIARWYVAEMILCIEEAHRLRCIHR 508 Query: 990 DIKPDNXXXXXXXXXXXXXFGLC--------------------KPLDSSNFPNLNEPDYT 1109 D+KPDN FGL K L + + + Sbjct: 509 DVKPDNFLISESGHLKISDFGLAFDGHWAHDQWYFTYQRHSLLKRLGIQIDGDAEDQKLS 568 Query: 1110 PGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQ-KNR-RMLAYSTVGTPDYIAPEVLLKK 1283 + L + L HW+ KN+ R +A S VGT Y+APEV+ Sbjct: 569 HDANIQSLGTTREDGSMEDDWIHPPTNGLLHWRDKNQTRTMARSVVGTSQYMAPEVIRGH 628 Query: 1284 GYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKF----PEEAKLSSET 1451 Y CDWWSLG I+YE L G+ PF SED T KI L F P + +S++ Sbjct: 629 PYDGRCDWWSLGVILYECLYGFTPFASEDRHQTKLKIHRHLQTLYFPVHRPTDKLVSADA 688 Query: 1452 KDLISKLLCNVEQRLGT-----------------------------------KGAHEIKA 1526 D+I+ LL E RL + A +IK+ Sbjct: 689 IDVINSLLQEKEFRLSSPKYKQNDAISSKPAKCSFYKPDSSNPSYQGHYVYPDDATDIKS 748 Query: 1527 HTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSS 1664 H +FRG+ WE++++ F+P V G DT+ F+ E + SS Sbjct: 749 HRFFRGINWEQIHRTSPPFIPMVRGWEDTRYFDDGEHPSDREDDSS 794
>Q811L6:MAST4_MOUSE Microtubule-associated serine/threonine-protein kinase 4 - Mus| musculus (Mouse) Length = 2618 Score = 217 bits (552), Expect = 2e-55 Identities = 123/350 (35%), Positives = 183/350 (52%), Gaps = 3/350 (0%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 R K DFE + +I GA+G V R K SR +AMKK+ K ++ R Q++ ER++ Sbjct: 560 RRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDI 619 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ ++V +Y SF+ L ++MEY+ GGD TL+ L D A+ Y AETVLA+ Sbjct: 620 LTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLAL 679 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLP 1136 E +H + +HRD+KPDN FGL K S NL E Sbjct: 680 EYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYE------------- 726 Query: 1137 DNTSRLTNPSAPKRTQQEQLSHWQKN-RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 H +K+ R L GTP+YIAPEV+L++GYG DWW+ Sbjct: 727 --------------------GHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWA 766 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKL-SSETKDLISKLL-CNVE 1487 +G I+YE LVG PF+ + P ++++ + +PE+ + + ++LI+ LL N Sbjct: 767 MGIILYEFLVGCVPFFGDTPEELFGQVIS--DEINWPEKDEAPPPDAQELITLLLRQNPL 824 Query: 1488 QRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEE 1637 +RLGT GA+E+K H +FR + W L + KA F+P++ E DT F+ E Sbjct: 825 ERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSE 874
>Q6P0Q8:MAST2_HUMAN Microtubule-associated serine/threonine-protein kinase 2 - Homo| sapiens (Human) Length = 1798 Score = 215 bits (548), Expect = 5e-55 Identities = 123/344 (35%), Positives = 181/344 (52%), Gaps = 3/344 (0%) Frame = +3 Query: 615 EDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS 794 EDFE + +I GA+G V L R K++R +AMKK+ K ++ R Q++ ER++L ++ Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 569 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V ++ SF L ++MEY+ GGD TLL L D + Y AETVLA+E +H + Sbjct: 570 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 629 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 +HRD+KPDN FGL K S NL E Sbjct: 630 GIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYE------------------- 670 Query: 1155 TNPSAPKRTQQEQLSHWQKN-RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 1331 H +K+ R L GTP+YIAPEV+L++GYG DWW++G I+Y Sbjct: 671 --------------GHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILY 716 Query: 1332 EMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE-EAKLSSETKDLISKLL-CNVEQRLGTK 1505 E LVG PF+ + P ++++ + +PE + L + +DL SKLL N +RLGT Sbjct: 717 EFLVGCVPFFGDTPEELFGQVIS--DEIVWPEGDEALPPDAQDLTSKLLHQNPLERLGTG 774 Query: 1506 GAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEE 1637 A+E+K H +F G+ W L + KA F+P++ E DT F+ E Sbjct: 775 SAYEVKQHPFFTGLDWTGLLRQKAEFIPQLESEDDTSYFDTRSE 818
>P54644:KRAC_DICDI RAC-family serine/threonine-protein kinase homolog - Dictyostelium| discoideum (Slime mold) Length = 444 Score = 215 bits (548), Expect = 5e-55 Identities = 128/379 (33%), Positives = 194/379 (51%), Gaps = 4/379 (1%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 K+GV DFELL ++G+G+FG+V R+K + VYAMK L K ++ +VEH +ERN+L Sbjct: 114 KVGVADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQ 173 Query: 783 EVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 +++ ++V L YSFQ ++ LY I++Y+ GG++ L + TED ++Y AE VLA+E Sbjct: 174 KINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEH 233 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H I+RD+KP+N FGLCK +G D Sbjct: 234 LHLSGVIYRDLKPENLLLTNEGHICMTDFGLCK------------------EGLLTPTDK 275 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 T + GTP+Y+APEVL GYG + DWWS G+ Sbjct: 276 TG----------------------------TFCGTPEYLAPEVLQGNGYGKQVDWWSFGS 307 Query: 1323 IMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLG 1499 ++YEML G PPFY++D RKI+ L FP +S + + L+ +LL + E+RL Sbjct: 308 LLYEMLTGLPPFYNQDVQEMYRKIM--MEKLSFPH--FISPDARSLLEQLLERDPEKRLA 363 Query: 1500 TKGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEK-FEETGAQVQSSSKA 1670 IK H +FR + WE+L+Q + F+P V G DT + F + + + + Sbjct: 364 DPNL--IKRHPFFRSIDWEQLFQKNIPPPFIPNVKGSADTSQIDPVFTDEAPSLTMAGEC 421 Query: 1671 GPWRKMLPSKDANFVGYTY 1727 + P + +F G+TY Sbjct: 422 A----LNPQQQKDFEGFTY 436
>Q6AX33:MAST3_XENLA Microtubule-associated serine/threonine-protein kinase 3 - Xenopus| laevis (African clawed frog) Length = 1482 Score = 215 bits (547), Expect = 7e-55 Identities = 125/349 (35%), Positives = 184/349 (52%), Gaps = 2/349 (0%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 R K DFE + +I GA+G V L R K +R +AMKK+ K ++ R Q+ V ER++ Sbjct: 391 RKKPCESDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIHQVFVERDI 450 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ ++V ++ SF+ L ++MEY+ GGD TLL L D ++ Y AETVLA+ Sbjct: 451 LTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMSRMYFAETVLAL 510 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLP 1136 E +H + +HRD+KPDN FGL K + NL E Sbjct: 511 EYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKVGLMNMTTNLYE------------- 557 Query: 1137 DNTSRLTNPSAPKRTQQEQLSHWQKN-RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 H +K+ R L GTP+YIAPEV+L++GYG DWW+ Sbjct: 558 --------------------GHIEKDTREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWA 597 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 +G I+YE LVG PF+ + P ++++ EEA L ++++DLI++LL N + Sbjct: 598 MGIILYEFLVGCVPFFGDTPEELFGQVISDDIIWPGGEEA-LPADSQDLITRLLRQNSLE 656 Query: 1491 RLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEE 1637 RLGT GA E+K HT+F + W L + KA FVP++ + DT F+ E Sbjct: 657 RLGTGGAQEVKQHTFFLSLDWNGLLRQKAEFVPQLEADDDTSYFDTRSE 705
>P28178:PK2_DICDI Protein kinase 2 - Dictyostelium discoideum (Slime mold)| Length = 479 Score = 214 bits (546), Expect = 9e-55 Identities = 124/382 (32%), Positives = 196/382 (51%), Gaps = 3/382 (0%) Frame = +3 Query: 615 EDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS 794 +DFELL +IG+G+FG+V ++K ++AMK L+K ++ R QV H K+E+ +L + Sbjct: 151 DDFELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISH 210 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 +IV L+Y+FQ + LY++++++ GG++ L R+ +E K Y AE V A++ +HK Sbjct: 211 PFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQ 270 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 + ++RD+KP+N FGL K ++++ D T Sbjct: 271 DIVYRDLKPENILLDSEGHICITDFGLSKKIETT--------------------DGT--- 307 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 ++ GTP+Y+APEVL G+G DWWSLG ++YE Sbjct: 308 -------------------------FTFCGTPEYLAPEVLNGHGHGCAVDWWSLGTLLYE 342 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRLGTKGA 1511 ML G PPFYS++ + +KI+N LK P +S E K L+ LL V++RLGTKG Sbjct: 343 MLTGLPPFYSQNVSTMYQKILN--GELKIP--TYISPEAKSLLEGLLTREVDKRLGTKGG 398 Query: 1512 HEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRK 1685 E+K H WF+ + WEKL +++ F P+V D + + S + Sbjct: 399 GEVKQHPWFKNIDWEKLDRKEVEVHFKPKVKSGTDISQIDPVFTQERPMDSLVETSALGD 458 Query: 1686 MLPSKDANFVGYTYKNFEIVND 1751 + KD +F G+TY I+ D Sbjct: 459 AM-GKDTSFEGFTYVADSILKD 479
>P27791:KAPCA_RAT cAMP-dependent protein kinase, alpha-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 214 bits (546), Expect = 9e-55 Identities = 124/388 (31%), Positives = 201/388 (51%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRL----QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 EQ ++ + L K + ++++ ++ ++ F+ + +G G+FG V L + K S + YA Sbjct: 12 EQESVKEFLAKAKEDFLKKWEDPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++VKL +SF+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + K R ++ G Sbjct: 192 V-----------------------------------------------KGR---TWTLCG 201 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TP+Y+APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G ++IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFKGPGDTSNFDDYEEEEIRVSINEKCG 345
>P36887:KAPCA_PIG cAMP-dependent protein kinase, alpha-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 214 bits (546), Expect = 9e-55 Identities = 124/388 (31%), Positives = 201/388 (51%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRL----QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 EQ ++ + L K + ++++ ++ ++ FE + +G G+FG V L + K + + +A Sbjct: 12 EQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++VKL YSF+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + K R ++ G Sbjct: 192 V-----------------------------------------------KGR---TWTLCG 201 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TP+Y+APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G ++IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFKGPGDTSNFDDYEEEEIRVSINEKCG 345
>P17612:KAPCA_HUMAN cAMP-dependent protein kinase, alpha-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 214 bits (546), Expect = 9e-55 Identities = 124/388 (31%), Positives = 201/388 (51%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRL----QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 EQ ++ + L K + ++++ ++ ++ FE + +G G+FG V L + K + + YA Sbjct: 12 EQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++VKL +SF+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + K R ++ G Sbjct: 192 V-----------------------------------------------KGR---TWTLCG 201 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TP+Y+APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G ++IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFKGPGDTSNFDDYEEEEIRVSINEKCG 345
>P25321:KAPCA_CRIGR cAMP-dependent protein kinase, alpha-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 214 bits (546), Expect = 9e-55 Identities = 124/388 (31%), Positives = 201/388 (51%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRL----QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 EQ ++ + L K + E+++ ++ ++ F+ + +G G+FG V L + K + + YA Sbjct: 12 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++VKL +SF+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + K R ++ G Sbjct: 192 V-----------------------------------------------KGR---TWTLCG 201 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TP+Y+APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G ++IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFKGPGDTSNFDDYEEEEIRVSINEKCG 345
>P68182:KAPCB_RAT cAMP-dependent protein kinase, beta-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 213 bits (543), Expect = 2e-54 Identities = 123/388 (31%), Positives = 193/388 (49%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRLQRH----KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 E ++ + L K + +++R + G+EDFE +G G+FG V L + K + YA Sbjct: 12 EVESVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++V+L YSF+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + + P+Y Sbjct: 192 VKGRTWTLCGTPEY---------------------------------------------- 205 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 +APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 206 ----LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G +IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFRGSGDTSNFDDYEEEEIRVSITEKCG 345
>P68181:KAPCB_MOUSE cAMP-dependent protein kinase, beta-catalytic subunit - Mus musculus| (Mouse) Length = 351 Score = 213 bits (543), Expect = 2e-54 Identities = 123/388 (31%), Positives = 193/388 (49%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRLQRH----KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 E ++ + L K + +++R + G+EDFE +G G+FG V L + K + YA Sbjct: 12 EVESVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++V+L YSF+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + + P+Y Sbjct: 192 VKGRTWTLCGTPEY---------------------------------------------- 205 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 +APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 206 ----LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G +IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFRGSGDTSNFDDYEEEEIRVSITEKCG 345
>P68180:KAPCB_CRIGR cAMP-dependent protein kinase, beta-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 213 bits (543), Expect = 2e-54 Identities = 123/388 (31%), Positives = 193/388 (49%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRLQRH----KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 E ++ + L K + +++R + G+EDFE +G G+FG V L + K + YA Sbjct: 12 EVESVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++V+L YSF+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + + P+Y Sbjct: 192 VKGRTWTLCGTPEY---------------------------------------------- 205 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 +APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 206 ----LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G +IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFRGSGDTSNFDDYEEEEIRVSITEKCG 345
>Q9P7J8:GAD8_SCHPO Serine/threonine-protein kinase gad8 - Schizosaccharomyces pombe| (Fission yeast) Length = 569 Score = 213 bits (543), Expect = 2e-54 Identities = 128/376 (34%), Positives = 198/376 (52%), Gaps = 3/376 (0%) Frame = +3 Query: 507 KLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT 686 KL D VP + L+ + Y Q + ++ FELL ++G+G+FG+V R++ Sbjct: 196 KLTDEWVPLHGGSGELR----VQMLYKPNQSTPLTIDAFELLKVVGKGSFGKVMQVRKRD 251 Query: 687 SRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLP 866 + +YA+K +KK+ ++ R +V+H AER +LA+V++ +IV L +SFQ LYL++ ++ Sbjct: 252 TSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVN 311 Query: 867 GGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXX 1046 GG++ L R+ AKFYIAE ++A+E +H+ N I+RD+KP+N Sbjct: 312 GGELFHHLQREGCFDTYRAKFYIAELLVALECLHEFNVIYRDLKPENILLDYTGHIALCD 371 Query: 1047 FGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRML 1226 FGLCK N + RT Sbjct: 372 FGLCK-------------------------------LNMAKTDRTN-------------- 386 Query: 1227 AYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWR 1406 + GTP+Y+APE+LL GY DWW+LG ++YEM+ G PPFY E+ RKI+ + Sbjct: 387 --TFCGTPEYLAPELLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKIL--Q 442 Query: 1407 SHLKFPEEAKLSSETKDLISKLLCNV-EQRLGTKGAHEIKAHTWFRGVQWEKL--YQMKA 1577 L+FP+ + + KDL+S LL E+RLG+ GA EIK H +F + W+KL +++ Sbjct: 443 DPLRFPD--NIDEKAKDLLSGLLTRAPEKRLGSGGAQEIKNHPFFDDIDWKKLCAKKIQP 500 Query: 1578 AFVPEVNGELDTQNFE 1625 F P V +DT NF+ Sbjct: 501 PFKPSVESAIDTSNFD 516
>P22612:KAPCG_HUMAN cAMP-dependent protein kinase, gamma-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 213 bits (542), Expect = 3e-54 Identities = 123/392 (31%), Positives = 197/392 (50%), Gaps = 9/392 (2%) Frame = +3 Query: 519 AEVPAEEQNNILKHLEKKETEYM----RLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT 686 A+ E++ ++ + L K +++ ++ + FE L +G G+FG V L R + Sbjct: 6 AKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQE 65 Query: 687 SRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLP 866 + YAMK L K ++++ QVEH+ E+ +L +D ++VKL +SF+D+ +LYL+MEY+P Sbjct: 66 TGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVP 125 Query: 867 GGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXX 1046 GG+M + L R +E A FY A+ VLA++ +H + IHRD+KP+N Sbjct: 126 GGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTD 185 Query: 1047 FGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRML 1226 FG K + + P+Y Sbjct: 186 FGFAKRVKGRTWTLCGTPEY---------------------------------------- 205 Query: 1227 AYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWR 1406 +APE++L KGY DWW+LG ++YEM VG+PPFY++ P+ KIV+ R Sbjct: 206 ----------LAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGR 255 Query: 1407 SHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK- 1574 ++FP +KLSS+ K L+ LL ++ +R G G +IK H WF W +Y+ K Sbjct: 256 --VRFP--SKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKV 311 Query: 1575 -AAFVPEVNGELDTQNFEKFEETGAQVQSSSK 1667 A F+P+ G D NF+ +EE ++ + K Sbjct: 312 EAPFIPKYTGPGDASNFDDYEEEELRISINEK 343
>Q8MJ44:KAPCA_CANFA cAMP-dependent protein kinase, alpha-catalytic subunit - Canis| familiaris (Dog) Length = 350 Score = 213 bits (542), Expect = 3e-54 Identities = 123/388 (31%), Positives = 201/388 (51%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRL----QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 EQ ++ + L K + ++++ ++ ++ FE + +G G+FG V L + K + + +A Sbjct: 11 EQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFA 70 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++VKL +SF+D+ LY++MEY+PGG+M + Sbjct: 71 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS 130 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 131 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 190 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + K R ++ G Sbjct: 191 V-----------------------------------------------KGR---TWTLCG 200 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TP+Y+APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 201 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 258 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G ++IK H WF W +YQ K A F+P Sbjct: 259 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIP 316 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 317 KFKGPGDTSNFDDYEEEEIRVSINEKCG 344
>O60307:MAST3_HUMAN Microtubule-associated serine/threonine-protein kinase 3 - Homo| sapiens (Human) Length = 1309 Score = 212 bits (540), Expect = 4e-54 Identities = 121/350 (34%), Positives = 182/350 (52%), Gaps = 3/350 (0%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 R K DFE + +I GA+G V L R + +R +A+KK+ K ++ R Q++ V ER++ Sbjct: 359 RRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDI 418 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ ++V ++ SF+ L ++MEY+ GGD TLL L D A+ Y AETVLA+ Sbjct: 419 LTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLAL 478 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLP 1136 E +H + +HRD+KPDN FGL K S NL E Sbjct: 479 EYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYE------------- 525 Query: 1137 DNTSRLTNPSAPKRTQQEQLSHWQKN-RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 H +K+ R + GTP+YIAPEV+ ++GYG DWW+ Sbjct: 526 --------------------GHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWA 565 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE-EAKLSSETKDLISKLLCNVE- 1487 +G ++YE LVG PF+ + P ++V+ + +PE + L ++ +DLI++LL Sbjct: 566 MGVVLYEFLVGCVPFFGDTPEELFGQVVS--DEIMWPEGDEALPADAQDLITRLLRQSPL 623 Query: 1488 QRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEE 1637 RLGT G HE+K H +F + W L + KA FVP++ E DT F+ E Sbjct: 624 DRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSE 673
>Q9MZD9:KAPCA_SHEEP cAMP-dependent protein kinase, alpha-catalytic subunit - Ovis aries| (Sheep) Length = 351 Score = 212 bits (540), Expect = 4e-54 Identities = 123/388 (31%), Positives = 200/388 (51%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRL----QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 EQ ++ + L K + ++++ ++ ++ FE + +G G+FG V L + + + YA Sbjct: 12 EQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHTETGNHYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++VKL +SF+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + K R ++ G Sbjct: 192 V-----------------------------------------------KGR---TWTLCG 201 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TP+Y+APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G ++IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFKGPGDTSNFDDYEEEEIRVSINEKCG 345
>P00517:KAPCA_BOVIN cAMP-dependent protein kinase, alpha-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 212 bits (540), Expect = 4e-54 Identities = 123/388 (31%), Positives = 200/388 (51%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRL----QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 EQ ++ + L K + ++++ ++ ++ FE + +G G+FG V L + + + YA Sbjct: 12 EQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++VKL +SF+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + K R ++ G Sbjct: 192 V-----------------------------------------------KGR---TWTLCG 201 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TP+Y+APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G ++IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFKGPGDTSNFDDYEEEEIRVSINEKCG 345
>P05132:KAPCA_MOUSE cAMP-dependent protein kinase, alpha-catalytic subunit - Mus musculus| (Mouse) Length = 351 Score = 212 bits (539), Expect = 6e-54 Identities = 123/388 (31%), Positives = 200/388 (51%), Gaps = 9/388 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRL----QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 EQ ++ + L K + ++++ ++ ++ F+ + +G G+FG V L + K S + YA Sbjct: 12 EQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++VKL +SF+D+ LY++MEY+ GG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + K R ++ G Sbjct: 192 V-----------------------------------------------KGR---TWTLCG 201 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 TP+Y+APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G ++IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAG 1673 + G DT NF+ +EE +V + K G Sbjct: 318 KFKGPGDTSNFDDYEEEEIRVSINEKCG 345
>Q3U214:MAST3_MOUSE Microtubule-associated serine/threonine-protein kinase 3 - Mus| musculus (Mouse) Length = 1321 Score = 211 bits (536), Expect = 1e-53 Identities = 123/350 (35%), Positives = 182/350 (52%), Gaps = 3/350 (0%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 R K DFE + +I GA+G V L R + +R +A+KK+ K ++ R Q++ V ER++ Sbjct: 381 RRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDI 440 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ ++V ++ SF+ L ++MEY+ GGD TLL L D A+ Y AETVLA+ Sbjct: 441 LTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLAL 500 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLP 1136 E +H + +HRD+KPDN FGL K S NL E Sbjct: 501 EYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYE------------- 547 Query: 1137 DNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTV-GTPDYIAPEVLLKKGYGMECDWWS 1313 H +K+ R V GTP+YIAPEV+ ++GYG DWW+ Sbjct: 548 --------------------GHIEKDAREFVDKQVCGTPEYIAPEVIFRQGYGKPVDWWA 587 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE-EAKLSSETKDLISKLL-CNVE 1487 +G I+YE LVG PF+ + P ++V+ + +PE + L + +DLI++LL + Sbjct: 588 MGVILYEFLVGCVPFFGDTPEELFGQVVS--DEIMWPEGDEALPLDAQDLITRLLRQSPM 645 Query: 1488 QRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEE 1637 RLGT G HE+K H +F + W L + KA FVP++ E DT F+ E Sbjct: 646 DRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSE 695
>P22204:DBF2_YEAST Cell cycle protein kinase DBF2 - Saccharomyces cerevisiae (Baker's| yeast) Length = 572 Score = 211 bits (536), Expect = 1e-53 Identities = 148/499 (29%), Positives = 238/499 (47%), Gaps = 27/499 (5%) Frame = +3 Query: 318 DKSKSPAVPASHGKDPGKPP---VDDAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKER 488 D+ P + S+ P K P + A S+ T++ V+ K Y HY + R++R Sbjct: 71 DEVSQPDMDVSNS--PKKLPPKFYERATSNKTQRVVSVCKMYFLEHYCDMFDYVISRRQR 128 Query: 489 -RWMLERKLQDAEVPAEEQ---NNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAF 656 + +LE Q +++P +Q N ++E + +R +R K DFE++T +G+G + Sbjct: 129 TKQVLEYLQQQSQLPNSDQIKLNEEWSSYLQREHQVLRKRRLKPKNRDFEMITQVGQGGY 188 Query: 657 GEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDE 836 G+V L R+K ++ V A+K L K + + + +HV ER++L S ++VKL Y+FQD + Sbjct: 189 GQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQ 248 Query: 837 FLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXX 1016 LYL ME++PGGD TLL+ L A+FYI+E A+ ++H Y HRD+KP+N Sbjct: 249 SLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLI 308 Query: 1017 XXXXXXXXXXFGLCKPLDSS-----------NFPNLNEPDYTPGKGAKPLPDNTSRLTNP 1163 FGL S+ +L P +T K + D Sbjct: 309 DAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFT----EKSIED-------- 356 Query: 1164 SAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLV 1343 +R QL + N A S VG+PDY+A EVL K Y D+WSLG +++E LV Sbjct: 357 ---RRKMYNQLREKEIN---YANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLV 410 Query: 1344 GYPPFYSEDPMSTCRKIVNWRSHLKFPEE----AKLSSETKDLISKLLCNVEQRLGTKGA 1511 GY PF T + W+ L+ P + A S T DLI++L+ + RL + Sbjct: 411 GYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITRLIADPINRL--RSF 468 Query: 1512 HEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKML 1691 +K ++F + + L M F P+++ E D F+ F + + K+ Sbjct: 469 EHVKRMSYFADINFSTLRSMIPPFTPQLDSETDAGYFDDFTSEADMAKYADVFKRQDKLT 528 Query: 1692 PSKD-----ANFVGYTYKN 1733 D + VG+T+++ Sbjct: 529 AMVDDSAVSSKLVGFTFRH 547
>P22694:KAPCB_HUMAN cAMP-dependent protein kinase, beta-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 209 bits (533), Expect = 3e-53 Identities = 120/386 (31%), Positives = 193/386 (50%), Gaps = 9/386 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRL----QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYA 704 E ++ + L K + ++++ ++ G+EDFE +G G+FG V L + K + YA Sbjct: 12 EVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYA 71 Query: 705 MKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMT 884 MK L K ++++ Q+EH E+ +L V+ ++V+L Y+F+D+ LY++MEY+PGG+M + Sbjct: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFS 131 Query: 885 LLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP 1064 L R +E A+FY A+ VL E +H + I+RD+KP+N FG K Sbjct: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR 191 Query: 1065 LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVG 1244 + + P+Y Sbjct: 192 VKGRTWTLCGTPEY---------------------------------------------- 205 Query: 1245 TPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFP 1424 +APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP Sbjct: 206 ----LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP 259 Query: 1425 EEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVP 1589 + SS+ KDL+ LL ++ +R G G +IK H WF W +YQ K A F+P Sbjct: 260 --SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 317 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSK 1667 + G DT NF+ +EE +V + K Sbjct: 318 KFRGSGDTSNFDDYEEEDIRVSITEK 343
>Q9Y2H9:MAST1_HUMAN Microtubule-associated serine/threonine-protein kinase 1 - Homo| sapiens (Human) Length = 1570 Score = 207 bits (528), Expect = 1e-52 Identities = 120/342 (35%), Positives = 179/342 (52%), Gaps = 3/342 (0%) Frame = +3 Query: 609 GVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 G DF+ + +I GA+G V L R + +R +AMKK+ K ++ R Q++ ER++L Sbjct: 370 GENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFA 429 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 ++ ++V ++ SF+ L ++MEY+ GGD TLL L + A+ Y AETVLA+E +H Sbjct: 430 ENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLH 489 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 + +HRD+KPDN FGL K S NL E Sbjct: 490 NYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYE----------------- 532 Query: 1149 RLTNPSAPKRTQQEQLSHWQKN-RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAI 1325 H +K+ R L GTP+YIAPEV+L++GYG DWW++G I Sbjct: 533 ----------------GHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGII 576 Query: 1326 MYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE-EAKLSSETKDLISKLL-CNVEQRLG 1499 +YE LVG PF+ + P ++++ + +PE + L +E + LIS LL N RLG Sbjct: 577 LYEFLVGCVPFFGDTPEELFGQVIS--DDILWPEGDEALPTEAQLLISSLLQTNPLVRLG 634 Query: 1500 TKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFE 1625 GA E+K H++FR + W L + KA F+P + E DT F+ Sbjct: 635 AGGAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFD 676
>P32328:DBF20_YEAST Serine/threonine-protein kinase DBF20 - Saccharomyces cerevisiae| (Baker's yeast) Length = 564 Score = 207 bits (527), Expect = 1e-52 Identities = 138/476 (28%), Positives = 229/476 (48%), Gaps = 19/476 (3%) Frame = +3 Query: 363 PGKPPVD---DAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPA 533 P K P D A S T++ V + Y ++Y + R++R + R L+ Sbjct: 76 PKKLPKDFHERASQSKTQRVVNVCQLYFLDYYCDMFDYVISRRQRTKQVLRYLEQQRSVK 135 Query: 534 EEQNNILKH----LEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVY 701 N +L ++E E +R +R K +DF++LT +G+G +G+V L ++K S + Sbjct: 136 NVSNKVLNEEWALYLQREHEVLRKRRLKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEIC 195 Query: 702 AMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMM 881 A+K L K + + + HV ER++L S ++VKL Y+FQD E LYL ME++PGGD Sbjct: 196 ALKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFR 255 Query: 882 TLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCK 1061 TLL+ L A+FYI+E A+ ++H+ Y HRD+KP+N FGL Sbjct: 256 TLLINTRILKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAA 315 Query: 1062 PLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRM---LAY 1232 S+ + K + L P+ +R+ +++ + R+ A Sbjct: 316 GTVSNE----------RIESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYAN 365 Query: 1233 STVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSH 1412 S VG+PDY+A EVL K Y D+WSLG +++E LVGY PF T + W+ Sbjct: 366 SMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKT 425 Query: 1413 LKFP----EEAKLSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAA 1580 L+ P A S T DLI++L+ + R+ + +++ ++F + +E L Sbjct: 426 LRRPRTEDRRAAFSDRTWDLITRLIADPINRV--RSFEQVRKMSYFAEINFETLRTSSPP 483 Query: 1581 FVPEVNGELDTQNFEKF---EETGAQVQSSSKAGPWRKMLPSK--DANFVGYTYKN 1733 F+P+++ E D F+ F E+ + M+ D+ VG+T+++ Sbjct: 484 FIPQLDDETDAGYFDDFTNEEDMAKYADVFKRQNKLSAMVDDSAVDSKLVGFTFRH 539
>Q810W7:MAST1_RAT Microtubule-associated serine/threonine-protein kinase 1 - Rattus| norvegicus (Rat) Length = 1570 Score = 206 bits (525), Expect = 2e-52 Identities = 119/342 (34%), Positives = 179/342 (52%), Gaps = 3/342 (0%) Frame = +3 Query: 609 GVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 G DF+ + +I GA+G V L R + +R +AMKK+ K ++ R Q++ ER++L Sbjct: 372 GESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFA 431 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 ++ ++V ++ SF+ L ++MEY+ GGD TLL L + A+ Y AETVLA+E +H Sbjct: 432 ENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLH 491 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 + +HRD+KPDN FGL K S NL E Sbjct: 492 NYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYE----------------- 534 Query: 1149 RLTNPSAPKRTQQEQLSHWQKN-RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAI 1325 H +K+ R L GTP+YIAPEV+L++GYG DWW++G I Sbjct: 535 ----------------GHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGII 578 Query: 1326 MYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE-EAKLSSETKDLISKLL-CNVEQRLG 1499 +YE LVG PF+ + P ++++ + +PE + L ++ + LIS LL N RLG Sbjct: 579 LYEFLVGCVPFFGDTPEELFGQVIS--DDILWPEGDEALPTDAQLLISSLLQTNPLVRLG 636 Query: 1500 TKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFE 1625 GA E+K H++FR + W L + KA F+P + E DT F+ Sbjct: 637 AGGAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFD 678
>Q9R1L5:MAST1_MOUSE Microtubule-associated serine/threonine-protein kinase 1 - Mus| musculus (Mouse) Length = 1566 Score = 206 bits (525), Expect = 2e-52 Identities = 119/342 (34%), Positives = 179/342 (52%), Gaps = 3/342 (0%) Frame = +3 Query: 609 GVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 G DF+ + +I GA+G V L R + +R +AMKK+ K ++ R Q++ ER++L Sbjct: 371 GESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFA 430 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 ++ ++V ++ SF+ L ++MEY+ GGD TLL L + A+ Y AETVLA+E +H Sbjct: 431 ENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLH 490 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 + +HRD+KPDN FGL K S NL E Sbjct: 491 NYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYE----------------- 533 Query: 1149 RLTNPSAPKRTQQEQLSHWQKN-RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAI 1325 H +K+ R L GTP+YIAPEV+L++GYG DWW++G I Sbjct: 534 ----------------GHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGII 577 Query: 1326 MYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE-EAKLSSETKDLISKLL-CNVEQRLG 1499 +YE LVG PF+ + P ++++ + +PE + L ++ + LIS LL N RLG Sbjct: 578 LYEFLVGCVPFFGDTPEELFGQVIS--DDILWPEGDEALPTDAQLLISSLLQTNPLVRLG 635 Query: 1500 TKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFE 1625 GA E+K H++FR + W L + KA F+P + E DT F+ Sbjct: 636 AGGAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFD 677
>Q922R0:PRKX_MOUSE Serine/threonine-protein kinase PRKX - Mus musculus (Mouse)| Length = 355 Score = 204 bits (518), Expect = 2e-51 Identities = 115/354 (32%), Positives = 186/354 (52%), Gaps = 5/354 (1%) Frame = +3 Query: 594 QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN 773 Q+ ++D++ + +G G FG V L +EKT R A+K + +++R Q +HV+ E+ Sbjct: 37 QKAGHSLQDWDTIATVGTGTFGRVNLVKEKTGRQYCALKIMSIPDVIRLKQEQHVQNEKA 96 Query: 774 LLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLA 953 +L E++ +++KL ++ D+ FLY++ME++PGG++ T L + + + FY E V A Sbjct: 97 VLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFYATEIVCA 156 Query: 954 IESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 IE +H ++RD+KP+N FG AK L Sbjct: 157 IEYLHSKEIVYRDLKPENILLDREGHIKLTDFGF----------------------AKKL 194 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 D T ++ GTP+Y+APEV+ KG+G DWW+ Sbjct: 195 VDRT----------------------------WTLCGTPEYLAPEVIQSKGHGRAVDWWA 226 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG +++EML G+PPF+ ++P +KI+ + + FP + +S KDLI KLL + + Sbjct: 227 LGILIFEMLSGFPPFFDDNPFGIYQKILACK--IDFPRQLDFTS--KDLIKKLLVVDRTR 282 Query: 1491 RLGT--KGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEKFEET 1640 RLG GA +IK H WFRGV+WE + Q +K VP+++G+ D NFE + E+ Sbjct: 283 RLGNMKNGAEDIKRHRWFRGVEWESVPQRKLKPPIVPKLSGDGDISNFETYPES 336
>O42626:NRC2_NEUCR Serine/threonine-protein kinase nrc-2 - Neurospora crassa| Length = 623 Score = 203 bits (517), Expect = 2e-51 Identities = 125/368 (33%), Positives = 191/368 (51%), Gaps = 7/368 (1%) Frame = +3 Query: 585 MRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKA 764 ++++ ++G + F+ + +IG+G G+V L +EK S +YAMK L K EM++R +++ A Sbjct: 230 IKVRNVEVGPQSFDKIKLIGKGDVGKVYLVKEKKSGRLYAMKVLSKKEMIKRNKIKRALA 289 Query: 765 ERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRK--DTLTEDEAKFYIA 938 E+ +LA + +IV LY+SFQ +++LYL MEY GG+ L + + ED+A+FY A Sbjct: 290 EQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCSGGEFFRALQTRPGKCIPEDDARFYAA 349 Query: 939 ETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGK 1118 E A+E +H +I+RD+KP+N F L K D P + Sbjct: 350 EVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKQSDPGGKPTMIIGKNGTST 409 Query: 1119 GAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGME 1298 + P D S + N S VGT +YIAPEV+ G+ Sbjct: 410 SSLPTIDTKSCIAN--------------------FRTNSFVGTEEYIAPEVIKGSGHTSA 449 Query: 1299 CDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEA---KLSSETKDLISK 1469 DWW+LG ++YEML G PF ++ +T I+ R + FP+ A ++S+ K LI K Sbjct: 450 VDWWTLGILIYEMLYGTTPFKGKNRNATFANIL--REDIPFPDHAGAPQISNLCKSLIRK 507 Query: 1470 LLCNVE-QRLGTK-GAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETG 1643 LL E +RLG + GA +IK H +FR QW + MK VP +DT NF +E+ Sbjct: 508 LLIKDENRRLGARAGASDIKTHPFFRTTQWALIRHMKPPIVPNQGRGIDTLNFRNVKESE 567 Query: 1644 AQVQSSSK 1667 + S S+ Sbjct: 568 SVDISGSR 575
>P34099:KAPC_DICDI cAMP-dependent protein kinase catalytic subunit - Dictyostelium| discoideum (Slime mold) Length = 648 Score = 202 bits (514), Expect = 4e-51 Identities = 112/347 (32%), Positives = 179/347 (51%), Gaps = 5/347 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVD 791 +++F+ + ++G G FG+V L + YAMK L K+ +++ QVEH+ +E+++L+ + Sbjct: 333 LKEFKQIRVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIH 392 Query: 792 SAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHK 971 +IV LY +FQD++ LYL+ EY+ GG++ T L + + AKFY AE VLA+E +HK Sbjct: 393 HPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHK 452 Query: 972 HNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSR 1151 N ++RD+KP+N FG K ++ F P+Y Sbjct: 453 QNIVYRDLKPENLLIDNQGHIKITDFGFAKRVEDRTFTLCGTPEY--------------- 497 Query: 1152 LTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 1331 +APE++ KG+G DWW+LG +++ Sbjct: 498 -----------------------------------LAPEIIQSKGHGKAVDWWALGILIF 522 Query: 1332 EMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT-- 1502 EML GYPPFY +D + KI+ R + FP + KDLI +LL + +RLG Sbjct: 523 EMLAGYPPFYDDDTFAIYNKILAGR--ITFP--LGFDVDAKDLIKRLLTADRTRRLGALK 578 Query: 1503 KGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKFEE 1637 GA ++K H WF + WE+LYQ + F+P++ + D+ NFE ++E Sbjct: 579 DGALDVKNHRWFSDINWERLYQRRDNGPFIPKIQHQGDSSNFEMYDE 625
>P16912:KDC2_DROME Protein kinase DC2 - Drosophila melanogaster (Fruit fly)| Length = 583 Score = 202 bits (513), Expect = 6e-51 Identities = 114/350 (32%), Positives = 172/350 (49%), Gaps = 5/350 (1%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 K ++D++++ +G G FG V LCR++ S AMK L +E++R Q+EHVK ERN+L Sbjct: 268 KYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILR 327 Query: 783 EVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 E+ +++ L +S +DD LY+I +Y+ GG++ T L T + FY AE V A+E Sbjct: 328 EIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEY 387 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H ++RD+KP+N FG K L + P+Y Sbjct: 388 LHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEY------------ 435 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 IAPE++ KG+ DWW+LG Sbjct: 436 --------------------------------------IAPEIIQSKGHNKAVDWWALGV 457 Query: 1323 IMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVE-QRLG 1499 ++YEMLVGYPPFY E P KI++ K E + KDLI KLL N +RLG Sbjct: 458 LIYEMLVGYPPFYDEQPFGIYEKILSG----KIEWERHMDPIAKDLIKKLLVNDRTKRLG 513 Query: 1500 T--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKFEE 1637 GA ++K H WF+ + W +Y ++K +P+V+ + DT+NF+ + E Sbjct: 514 NMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPE 563
>P12688:YPK1_YEAST Serine/threonine-protein kinase YPK1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 680 Score = 201 bits (512), Expect = 8e-51 Identities = 127/400 (31%), Positives = 201/400 (50%), Gaps = 4/400 (1%) Frame = +3 Query: 579 EYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHV 758 +Y + + ++DF+LL +IG+G+FG+V R+K ++ VYA+K ++KS ++ + +V H Sbjct: 333 DYKPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHT 392 Query: 759 KAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIA 938 AER +LA VD +IV L +SFQ E LY ++ ++ GG++ L ++ A+FY A Sbjct: 393 LAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTA 452 Query: 939 ETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGK 1118 E + A++++HK + ++RD+KP+N FGLCK N+ + D T Sbjct: 453 ELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCK-------LNMKDDDKTD-- 503 Query: 1119 GAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGME 1298 + GTP+Y+APE+LL GY Sbjct: 504 --------------------------------------TFCGTPEYLAPELLLGLGYTKA 525 Query: 1299 CDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC 1478 DWW+LG ++YEML G PP+Y ED +KI+ + L FP+ + KDL+ LL Sbjct: 526 VDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QEPLVFPD--GFDRDAKDLLIGLLS 581 Query: 1479 -NVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKA---AFVPEVNGELDTQNFEKFEETGA 1646 + +RLG GA EI+ H +F + W++L MK + P V+ +DT NF+ EE Sbjct: 582 RDPTRRLGYNGADEIRNHPFFSQLSWKRLL-MKGYIPPYKPAVSNSMDTSNFD--EEFTR 638 Query: 1647 QVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAG 1766 + S + + S F G+TY E + V G Sbjct: 639 EKPIDSVVDEY--LSESVQKQFGGWTYVGNEQLGSSMVQG 676
>P18961:YPK2_YEAST Serine/threonine-protein kinase YPK2/YKR2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 677 Score = 200 bits (508), Expect = 2e-50 Identities = 125/399 (31%), Positives = 201/399 (50%), Gaps = 3/399 (0%) Frame = +3 Query: 579 EYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHV 758 +Y + + ++DF+LL +IG+G+FG+V R+K ++ +YA+K L+K+ ++ + +V H Sbjct: 330 DYKPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHT 389 Query: 759 KAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIA 938 AER +LA VD +IV L +SFQ E LYL++ ++ GG++ L + + ++FYIA Sbjct: 390 LAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIA 449 Query: 939 ETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGK 1118 E + A++S+HK + I+RD+KP+N FGLCK N+ + D T Sbjct: 450 ELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCK-------LNMKDNDKTD-- 500 Query: 1119 GAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGME 1298 + GTP+Y+APE+LL +GY Sbjct: 501 --------------------------------------TFCGTPEYLAPEILLGQGYTKT 522 Query: 1299 CDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC 1478 DWW+LG ++YEM+ G PP+Y E+ +KI+ + L FP+ KDL+ LL Sbjct: 523 VDWWTLGILLYEMMTGLPPYYDENVPVMYKKIL--QQPLLFPD--GFDPAAKDLLIGLLS 578 Query: 1479 -NVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKFEETGAQ 1649 + +RLG G EI+ H +F+ + W+KL + P V E+DT NF+ +E + Sbjct: 579 RDPSRRLGVNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFD--QEFTKE 636 Query: 1650 VQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAG 1766 S + + S F G+TY E + D G Sbjct: 637 KPIDSVVDEY--LSASIQKQFGGWTYIGDEQLGDSPSQG 673
>P12370:KAPC_DROME cAMP-dependent protein kinase catalytic subunit - Drosophila| melanogaster (Fruit fly) Length = 353 Score = 199 bits (507), Expect = 3e-50 Identities = 112/373 (30%), Positives = 185/373 (49%), Gaps = 5/373 (1%) Frame = +3 Query: 564 EKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRG 743 E+ E ++ R + ++DFE + +G G+FG V + + K ++ YAMK L K ++++ Sbjct: 27 EEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLK 86 Query: 744 QVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEA 923 QVEH E+ +L + ++V L Y F+D+ LY+++EY+PGG+M + L + +E + Sbjct: 87 QVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHS 146 Query: 924 KFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPD 1103 +FY A+ VLA E +H + I+RD+KP+N FG K + + P+ Sbjct: 147 RFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPE 206 Query: 1104 YTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKK 1283 Y +APE++L K Sbjct: 207 Y--------------------------------------------------LAPEIILSK 216 Query: 1284 GYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLI 1463 GY DWW+LG ++YEM GYPPF+++ P+ KIV+ + ++FP + S+ KDL+ Sbjct: 217 GYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP--SHFGSDLKDLL 272 Query: 1464 SKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEK 1628 LL ++ +R G G ++IK WF W ++Q K A F+P G DT NF+ Sbjct: 273 RNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDD 332 Query: 1629 FEETGAQVQSSSK 1667 +EE ++ S+ K Sbjct: 333 YEEEALRISSTEK 345
>P51817:PRKX_HUMAN Serine/threonine-protein kinase PRKX - Homo sapiens (Human)| Length = 358 Score = 199 bits (505), Expect = 5e-50 Identities = 109/347 (31%), Positives = 176/347 (50%), Gaps = 5/347 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVD 791 ++DF+ L +G G FG V L +EKT++ +A+K + +++R Q +HV E+++L EV Sbjct: 46 LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVS 105 Query: 792 SAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHK 971 ++++L++++ D+ FLY++MEY+PGG++ + L + + FY AE + AIE +H Sbjct: 106 HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHS 165 Query: 972 HNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSR 1151 ++RD+KP+N FG K L + P+Y Sbjct: 166 KEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEY--------------- 210 Query: 1152 LTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 1331 +APEV+ KG+G DWW+LG +++ Sbjct: 211 -----------------------------------LAPEVIQSKGHGRAVDWWALGILIF 235 Query: 1332 EMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT-- 1502 EML G+PPF+ ++P +KI+ + FP L KDLI KLL + +RLG Sbjct: 236 EMLSGFPPFFDDNPFGIYQKIL--AGKIDFPRH--LDFHVKDLIKKLLVVDRTRRLGNMK 291 Query: 1503 KGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEKFEE 1637 GA+++K H WFR V WE + Q +K VP++ G+ DT NFE + E Sbjct: 292 NGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYPE 338
>P50530:SCK1_SCHPO Serine/threonine-protein kinase sck1 - Schizosaccharomyces pombe| (Fission yeast) Length = 696 Score = 198 bits (504), Expect = 6e-50 Identities = 143/429 (33%), Positives = 206/429 (48%), Gaps = 16/429 (3%) Frame = +3 Query: 537 EQNNILKHLE---KKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAM 707 E ++ K LE K ET Y ++ + G EDF L +IG+G FG+V L R+ + +YAM Sbjct: 271 EPLDLTKSLEGEIKVETIYEHIEHVRYGPEDFTALRLIGKGTFGQVYLVRKNDTNRIYAM 330 Query: 708 KKLKKSEMLRRGQVEHVKAERNLLAEV---DSAYIVKLYYSFQDDEFLYLIMEYLPGGDM 878 KK+ K ++R+ +V H ERN+L +S +IV L +SFQ LYLI +Y+ GG++ Sbjct: 331 KKISKKLIVRKKEVTHTLGERNILVRTSLDESPFIVGLKFSFQTASDLYLITDYMSGGEL 390 Query: 879 MTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLC 1058 L + E AKFYIAE VLA+E +HKH+ I+RD+KP+N FGL Sbjct: 391 FWHLQHEGRFPEQRAKFYIAELVLALEHLHKHDIIYRDLKPENILLDADGHIALCDFGLS 450 Query: 1059 KPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYST 1238 K S+N TN + Sbjct: 451 KANLSAN-----------------------ATTN------------------------TF 463 Query: 1239 VGTPDYIAPEVLLK-KGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHL 1415 GT +Y+APEVLL+ KGY + D+WSLG +++EM G+ PFY+ D R I + + Sbjct: 464 CGTTEYLAPEVLLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGK--V 521 Query: 1416 KFPEEAKLSSETKDLISKLL-CNVEQRLG-TKGAHEIKAHTWFRGVQWEKLYQMKA--AF 1583 +FP + LSSE + + LL N RLG E+K H +F + W+ L + K F Sbjct: 522 RFP-KGVLSSEGRSFVRGLLNRNPNHRLGAVADTTELKEHPFFADINWDLLSKKKVQPPF 580 Query: 1584 VPEVNGELDTQNFEK-FEETGAQ-VQSSSKAGPWRKMLPSKDA---NFVGYTYKNFEIVN 1748 P V +LD NF+K F T + + S P P + F G+T+ N I Sbjct: 581 KPNVQNDLDVSNFDKEFTNTNVKNINIVSNVDPANASTPLSNTIQDRFRGFTFVNKSIDE 640 Query: 1749 DDEVAGIAE 1775 + G+ E Sbjct: 641 QFQNLGLQE 649
>Q10364:SCK2_SCHPO Serine/threonine-protein kinase sck2 - Schizosaccharomyces pombe| (Fission yeast) Length = 646 Score = 197 bits (500), Expect = 2e-49 Identities = 125/358 (34%), Positives = 184/358 (51%), Gaps = 8/358 (2%) Frame = +3 Query: 576 TEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEH 755 T + L +H G +DF L +IG+G FG+V L R+K + VYAMK L K ++RR +V H Sbjct: 251 TVFQPLSQHSYGPDDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAH 310 Query: 756 VKAERNLLAEV---DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAK 926 ER++L + DS +IV L +SFQ + LYL+ +Y+ GG++ L + E+ AK Sbjct: 311 TVGERDILVQTSAADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAK 370 Query: 927 FYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDY 1106 FYIAE +LA++++HK ++RD+KP+N FGL K Sbjct: 371 FYIAELLLALQALHKRGIVYRDLKPENILLDVQGHIALCDFGLSK--------------- 415 Query: 1107 TPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLL-KK 1283 N S T+ + GT DY+APEV+L + Sbjct: 416 ----------------ANLSVGTTTR----------------TFCGTTDYLAPEVILDEA 443 Query: 1284 GYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLI 1463 GY M D+WSLG ++YEM G+ PFY+++ + IV + ++FP LS E +DLI Sbjct: 444 GYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGK--VRFP-RGLLSVEARDLI 500 Query: 1464 SKLL-CNVEQRLGTKG-AHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFE 1625 LL N + RLG G E+ H +F G+ W+KL ++ F P V GE+D NF+ Sbjct: 501 KLLLNRNPKHRLGAHGDVEEVMKHPFFDGIDWKKLAAKEISPPFKPIVEGEIDVSNFD 558
>P42818:KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 - Arabidopsis thaliana| (Mouse-ear cress) Length = 465 Score = 195 bits (495), Expect = 7e-49 Identities = 117/370 (31%), Positives = 186/370 (50%), Gaps = 12/370 (3%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G++DFE++ ++G+GAFG+V R+K + +YAMK ++K ++ + E++KAER++L + Sbjct: 129 VGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTK 188 Query: 786 VDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESI 965 +D +IV+L YSFQ LYL+++++ GG + L + ED A+ Y AE V A+ + Sbjct: 189 IDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHL 248 Query: 966 HKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNT 1145 H+ +HRD+KP+N FGL K + + N Sbjct: 249 HEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSN------------------- 289 Query: 1146 SRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAI 1325 S GT +Y+APE++ KG+ DWWS+G + Sbjct: 290 -----------------------------SMCGTTEYMAPEIVRGKGHDKAADWWSVGIL 320 Query: 1326 MYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT 1502 +YEML G PPF +KIV + +K P+ LS+E ++ LL E+RLG+ Sbjct: 321 LYEMLTGKPPFLGSKG-KIQQKIV--KDKIKLPQ--FLSNEAHAILKGLLQKEPERRLGS 375 Query: 1503 --KGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEK-------FEETGAQ 1649 GA EIK H WF+G+ W+KL ++ +F PEV+G NF+K + + Sbjct: 376 GLSGAEEIKQHKWFKGINWKKLEAREVMPSFKPEVSGRQCIANFDKCWTDMSVLDSPASS 435 Query: 1650 VQSSSKAGPW 1679 S KA P+ Sbjct: 436 PSSDPKANPF 445
>Q6TJY3:KS6B1_BOVIN Ribosomal protein S6 kinase beta-1 - Bos taurus (Bovine)| Length = 527 Score = 194 bits (493), Expect = 1e-48 Identities = 133/403 (33%), Positives = 197/403 (48%), Gaps = 11/403 (2%) Frame = +3 Query: 552 LKHLEKKETEYMRLQR--HKMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKL 716 ++H EK E + R K+ E FELL ++G+G +G+V R+ T + ++AMK L Sbjct: 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVL 125 Query: 717 KKSEMLRRGQ-VEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLM 893 KK+ ++R + H KAERN+L EV +IV L Y+FQ LYLI+EYL GG++ L Sbjct: 126 KKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLE 185 Query: 894 RKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDS 1073 R+ ED A FY+AE +A+ +H+ I+RD+KP+N FGLCK Sbjct: 186 REGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK---- 241 Query: 1074 SNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPD 1253 + + D T + ++ GT + Sbjct: 242 -----------------ESIHDGT--------------------------VTHTFCGTIE 258 Query: 1254 YIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEA 1433 Y+APE+L++ G+ DWWSLGA+MY+ML G PPF E+ T KI+ + +L Sbjct: 259 YMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNL----PP 314 Query: 1434 KLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMKA--AFVPEVN 1598 L+ E +DL+ KLL N RLG A E++AH +FR + WE+L K F P + Sbjct: 315 YLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 374 Query: 1599 GELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY 1727 E D F+ V S + + S + F+G+TY Sbjct: 375 SEEDVSQFDSKFTRQTPVDSPDDSA----LSESANQVFLGFTY 413
>Q39030:KPK19_ARATH Serine/threonine-protein kinase AtPK19 - Arabidopsis thaliana| (Mouse-ear cress) Length = 471 Score = 194 bits (493), Expect = 1e-48 Identities = 118/370 (31%), Positives = 187/370 (50%), Gaps = 12/370 (3%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G+EDFE+L ++G+GAFG+V R+K + +YAMK ++K +++ + E++KAER++L + Sbjct: 135 VGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTK 194 Query: 786 VDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESI 965 +D +IV+L YSFQ LYL+++++ GG + L + ED A+ Y AE V A+ + Sbjct: 195 IDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHL 254 Query: 966 HKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNT 1145 H+ +HRD+KP+N FGL K + + N Sbjct: 255 HEKGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSN------------------- 295 Query: 1146 SRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAI 1325 S GT +Y+APE++ KG+ DWWS+G + Sbjct: 296 -----------------------------SMCGTTEYMAPEIVRGKGHDKAADWWSVGIL 326 Query: 1326 MYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT 1502 +YEML G PPF +KIV + +K P+ LS+E L+ LL E+RLG+ Sbjct: 327 LYEMLTGKPPFLGSKG-KIQQKIV--KDKIKLPQ--FLSNEAHALLKGLLQKEPERRLGS 381 Query: 1503 --KGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEK-------FEETGAQ 1649 GA EIK H WF+ + W+KL +++ +F P V+G NF+K + + Sbjct: 382 GPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVSGRQCIANFDKCWTDMSVLDSPASS 441 Query: 1650 VQSSSKAGPW 1679 S +KA P+ Sbjct: 442 PNSDAKANPF 451
>P67999:KS6B1_RAT Ribosomal protein S6 kinase beta-1 - Rattus norvegicus (Rat)| Length = 525 Score = 194 bits (492), Expect = 2e-48 Identities = 133/403 (33%), Positives = 197/403 (48%), Gaps = 11/403 (2%) Frame = +3 Query: 552 LKHLEKKETEYMRLQR--HKMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKL 716 ++H EK E + R K+ E FELL ++G+G +G+V R+ T + ++AMK L Sbjct: 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVL 125 Query: 717 KKSEMLRRGQ-VEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLM 893 KK+ ++R + H KAERN+L EV +IV L Y+FQ LYLI+EYL GG++ L Sbjct: 126 KKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLE 185 Query: 894 RKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDS 1073 R+ ED A FY+AE +A+ +H+ I+RD+KP+N FGLCK Sbjct: 186 REGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK---- 241 Query: 1074 SNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPD 1253 + + D T + ++ GT + Sbjct: 242 -----------------ESIHDGT--------------------------VTHTFCGTIE 258 Query: 1254 YIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEA 1433 Y+APE+L++ G+ DWWSLGA+MY+ML G PPF E+ T KI+ + +L Sbjct: 259 YMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNL----PP 314 Query: 1434 KLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMKA--AFVPEVN 1598 L+ E +DL+ KLL N RLG A E++AH +FR + WE+L K F P + Sbjct: 315 YLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 374 Query: 1599 GELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY 1727 E D F+ V S + + S + F+G+TY Sbjct: 375 SEEDVSQFDSKFTRQTPVDSPDDS----TLSESANQVFLGFTY 413
>P67998:KS6B1_RABIT Ribosomal protein S6 kinase beta-1 - Oryctolagus cuniculus (Rabbit)| Length = 525 Score = 194 bits (492), Expect = 2e-48 Identities = 133/403 (33%), Positives = 197/403 (48%), Gaps = 11/403 (2%) Frame = +3 Query: 552 LKHLEKKETEYMRLQR--HKMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKL 716 ++H EK E + R K+ E FELL ++G+G +G+V R+ T + ++AMK L Sbjct: 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVL 125 Query: 717 KKSEMLRRGQ-VEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLM 893 KK+ ++R + H KAERN+L EV +IV L Y+FQ LYLI+EYL GG++ L Sbjct: 126 KKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLE 185 Query: 894 RKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDS 1073 R+ ED A FY+AE +A+ +H+ I+RD+KP+N FGLCK Sbjct: 186 REGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK---- 241 Query: 1074 SNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPD 1253 + + D T + ++ GT + Sbjct: 242 -----------------ESIHDGT--------------------------VTHTFCGTIE 258 Query: 1254 YIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEA 1433 Y+APE+L++ G+ DWWSLGA+MY+ML G PPF E+ T KI+ + +L Sbjct: 259 YMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNL----PP 314 Query: 1434 KLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMKA--AFVPEVN 1598 L+ E +DL+ KLL N RLG A E++AH +FR + WE+L K F P + Sbjct: 315 YLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 374 Query: 1599 GELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY 1727 E D F+ V S + + S + F+G+TY Sbjct: 375 SEEDVSQFDSKFTRQTPVDSPDDS----TLSESANQVFLGFTY 413
>Q8BSK8:KS6B1_MOUSE Ribosomal protein S6 kinase beta-1 - Mus musculus (Mouse)| Length = 525 Score = 194 bits (492), Expect = 2e-48 Identities = 133/403 (33%), Positives = 197/403 (48%), Gaps = 11/403 (2%) Frame = +3 Query: 552 LKHLEKKETEYMRLQR--HKMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKL 716 ++H EK E + R K+ E FELL ++G+G +G+V R+ T + ++AMK L Sbjct: 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVL 125 Query: 717 KKSEMLRRGQ-VEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLM 893 KK+ ++R + H KAERN+L EV +IV L Y+FQ LYLI+EYL GG++ L Sbjct: 126 KKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLE 185 Query: 894 RKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDS 1073 R+ ED A FY+AE +A+ +H+ I+RD+KP+N FGLCK Sbjct: 186 REGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK---- 241 Query: 1074 SNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPD 1253 + + D T + ++ GT + Sbjct: 242 -----------------ESIHDGT--------------------------VTHTFCGTIE 258 Query: 1254 YIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEA 1433 Y+APE+L++ G+ DWWSLGA+MY+ML G PPF E+ T KI+ + +L Sbjct: 259 YMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNL----PP 314 Query: 1434 KLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMKA--AFVPEVN 1598 L+ E +DL+ KLL N RLG A E++AH +FR + WE+L K F P + Sbjct: 315 YLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 374 Query: 1599 GELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY 1727 E D F+ V S + + S + F+G+TY Sbjct: 375 SEEDVSQFDSKFTRQTPVDSPDDS----TLSESANQVFLGFTY 413
>P23443:KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 - Homo sapiens (Human)| Length = 525 Score = 194 bits (492), Expect = 2e-48 Identities = 133/403 (33%), Positives = 197/403 (48%), Gaps = 11/403 (2%) Frame = +3 Query: 552 LKHLEKKETEYMRLQR--HKMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKL 716 ++H EK E + R K+ E FELL ++G+G +G+V R+ T + ++AMK L Sbjct: 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVL 125 Query: 717 KKSEMLRRGQ-VEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLM 893 KK+ ++R + H KAERN+L EV +IV L Y+FQ LYLI+EYL GG++ L Sbjct: 126 KKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLE 185 Query: 894 RKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDS 1073 R+ ED A FY+AE +A+ +H+ I+RD+KP+N FGLCK Sbjct: 186 REGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK---- 241 Query: 1074 SNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPD 1253 + + D T + ++ GT + Sbjct: 242 -----------------ESIHDGT--------------------------VTHTFCGTIE 258 Query: 1254 YIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEA 1433 Y+APE+L++ G+ DWWSLGA+MY+ML G PPF E+ T KI+ + +L Sbjct: 259 YMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNL----PP 314 Query: 1434 KLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMKA--AFVPEVN 1598 L+ E +DL+ KLL N RLG A E++AH +FR + WE+L K F P + Sbjct: 315 YLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 374 Query: 1599 GELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTY 1727 E D F+ V S + + S + F+G+TY Sbjct: 375 SEEDVSQFDSKFTRQTPVDSPDDS----TLSESANQVFLGFTY 413
>P53739:KN8R_YEAST Probable serine/threonine-protein kinase YNR047W - Saccharomyces| cerevisiae (Baker's yeast) Length = 893 Score = 191 bits (484), Expect = 1e-47 Identities = 122/365 (33%), Positives = 181/365 (49%), Gaps = 4/365 (1%) Frame = +3 Query: 507 KLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT 686 K+ D P + K K + M +G + FE + ++G+G G+V L REK Sbjct: 464 KISDFPEPRRSRRLRTKSFSNKFQDIM------VGPQSFEKIRLLGQGDVGKVFLVREKK 517 Query: 687 SRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLP 866 + VYA+K L K EM++R +++ V E+ +LA + +IV LY+SFQ +++LYL MEY Sbjct: 518 TNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCM 577 Query: 867 GGDMMTLLMRKDT--LTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXX 1040 GG+ L + T + ED+A+FY +E A+E +H +I+RD+KP+N Sbjct: 578 GGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIML 637 Query: 1041 XXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRR 1220 F L S P G L D S RT Sbjct: 638 SDFDLSIQAKDSKVP------VVKGSAQSTLVDTKI----CSDGFRTN------------ 675 Query: 1221 MLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVN 1400 S VGT +YIAPEV+ G+ DWW+LG ++YEML G+ PF ++ T I+ Sbjct: 676 ----SFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNIL- 730 Query: 1401 WRSHLKFPEEAKLSSETKDLISKLLC-NVEQRLGTK-GAHEIKAHTWFRGVQWEKLYQMK 1574 ++ + FP ++S KDLI KLL N +RLG K GA ++K H +F+ VQW L + Sbjct: 731 -KNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRNQE 789 Query: 1575 AAFVP 1589 +P Sbjct: 790 PPLIP 794
>Q09831:PPK14_SCHPO Serine/threonine-protein kinase ppk14 - Schizosaccharomyces pombe| (Fission yeast) Length = 566 Score = 190 bits (483), Expect = 2e-47 Identities = 123/338 (36%), Positives = 180/338 (53%), Gaps = 7/338 (2%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 ++G FE + ++G+G G V L REK S YAMK L K EM++R + + AE+++LA Sbjct: 189 EVGPSSFEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILA 248 Query: 783 EVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKD--TLTEDEAKFYIAETVLAI 956 + +IV LY+SFQ DE+LYL MEY GG+ L R+ L+E+EAKFYIAE A+ Sbjct: 249 TSNHPFIVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAAL 308 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLP 1136 E +H +I+RD+KP+N F L K +S+ P + + P Sbjct: 309 EYLHLMGFIYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPS------A 362 Query: 1137 DNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSL 1316 N L S ++ ++ N S VGT +YIAPEV+ G+ DWW+L Sbjct: 363 QNAYALDTKSC--------IADFRTN------SFVGTEEYIAPEVIKGCGHTSAVDWWTL 408 Query: 1317 GAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEA---KLSSETKDLISKLLCNVE 1487 G + YEML PF ++ T I++ + FPE A +SS K+LI KLL E Sbjct: 409 GILFYEMLYATTPFKGKNRNMTFSNILH--KDVIFPEYADAPSISSLCKNLIRKLLVKDE 466 Query: 1488 -QRLGTK-GAHEIKAHTWFRGVQWEKLYQMKAAFVPEV 1595 RLG++ GA ++K H +F+ VQW L + +P++ Sbjct: 467 NDRLGSQAGAADVKLHPFFKNVQWALLRHTEPPIIPKL 504
>Q9UK32:KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 - Homo sapiens (Human)| Length = 745 Score = 190 bits (483), Expect = 2e-47 Identities = 123/383 (32%), Positives = 197/383 (51%), Gaps = 6/383 (1%) Frame = +3 Query: 495 MLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLC 674 M++ +++ E + ++K + T +++ K FELL ++G+G+FG+V L Sbjct: 33 MVDEPMEEGEADSCHDEGVVKEIPI--THHVKEGYEKADPAQFELLKVLGQGSFGKVFLV 90 Query: 675 REKT---SRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLY 845 R+KT + +YAMK LKK+ + R +V K ER++L EV+ +IVKL+Y+FQ + LY Sbjct: 91 RKKTGPDAGQLYAMKVLKKASLKVRDRVR-TKMERDILVEVNHPFIVKLHYAFQTEGKLY 149 Query: 846 LIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXX 1025 LI+++L GGD+ T L ++ TE++ KFY+AE LA++ +H+ ++RD+KP+N Sbjct: 150 LILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEI 209 Query: 1026 XXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHW 1205 FGL K + QE+ Sbjct: 210 GHIKLTDFGLSK-------------------------------------ESVDQEK---- 228 Query: 1206 QKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTC 1385 AYS GT +Y+APEV+ ++G+ DWWS G +M+EML G PF +D T Sbjct: 229 ------KAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETM 282 Query: 1386 RKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGAHEIKAHTWFRGVQWEKL 1562 I+ ++ L P+ LS+E + L+ L N RLG++G EIK H +F + W+KL Sbjct: 283 NMIL--KAKLGMPQ--FLSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFFANIDWDKL 338 Query: 1563 Y--QMKAAFVPEVNGELDTQNFE 1625 Y +++ F P DT F+ Sbjct: 339 YKREVQPPFKPASGKPDDTFCFD 361 Score = 91.3 bits (225), Expect = 1e-17 Identities = 77/311 (24%), Positives = 132/311 (42%), Gaps = 4/311 (1%) Frame = +3 Query: 615 EDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS 794 E +EL IG G++ + C T+ +A+K + KS +R E ++ L+ Sbjct: 424 EVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKS---KRDPSEEIEI---LMRYGQH 477 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 I+ L F D ++YL+ + + GG+++ ++++ +E EA + ++ +H Sbjct: 478 PNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQ 537 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 +HRD+KP N +S++ ++ D+ AK L L Sbjct: 538 GVVHRDLKPSNILYMD---------------ESASADSIRICDFG---FAKQLRGENGLL 579 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 P T +++APEVL+++GY CD WSLG + Y Sbjct: 580 LTPCY-------------------------TANFVAPEVLMQQGYDAACDIWSLGVLFYT 614 Query: 1335 MLVGYPPFY---SEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT 1502 ML GY PF ++ P +I N + L +S KDL+S +L + QR Sbjct: 615 MLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRY-- 672 Query: 1503 KGAHEIKAHTW 1535 A +I H+W Sbjct: 673 -TAEQILKHSW 682
>Q9USX7:PPK22_SCHPO Serine/threonine-protein kinase ppk22 - Schizosaccharomyces pombe| (Fission yeast) Length = 526 Score = 190 bits (482), Expect = 2e-47 Identities = 118/348 (33%), Positives = 180/348 (51%), Gaps = 7/348 (2%) Frame = +3 Query: 588 RLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAE 767 ++ R ++ FE + ++G+G G+V L R+K++ ++AMK L K EM++R +V V AE Sbjct: 144 KISRVEVTPHSFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAE 203 Query: 768 RNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLL--MRKDTLTEDEAKFYIAE 941 + +L + +IV LY+SFQ ++LYL MEY GG+ L + K L E +A FY AE Sbjct: 204 QEILTKSKHPFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAE 263 Query: 942 TVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKG 1121 A+E +H +I+RD+KP+N F L KP+ P + P ++ Sbjct: 264 VTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQ 323 Query: 1122 AKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMEC 1301 KP D S +N S VGT +YIAPEV+ G+ + Sbjct: 324 EKPALDTNSYFSN--------------------FRTNSFVGTEEYIAPEVIRSCGHTVAV 363 Query: 1302 DWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE---EAKLSSETKDLISKL 1472 DWW+LG +YE+L G PF ++ +T I+ S + FPE +SS K LI +L Sbjct: 364 DWWTLGIFIYEILYGTTPFKGKNRHATFSNIL--YSDVSFPEYHGAPNVSSTCKSLIRRL 421 Query: 1473 LCNVE-QRLGT-KGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELD 1610 L E +R G+ GA +IK H +FR +QW L MK +P++ ++ Sbjct: 422 LVKDESKRCGSVAGASDIKQHPFFRHIQWALLRSMKPPIIPKIEDGME 469
>P06244:KAPA_YEAST cAMP-dependent protein kinase type 1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 397 Score = 190 bits (482), Expect = 2e-47 Identities = 129/421 (30%), Positives = 196/421 (46%), Gaps = 29/421 (6%) Frame = +3 Query: 462 KSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKK--ETEYMRLQRH----------- 602 KSL DR+ + + + E A E N K +EK+ ET+ Q H Sbjct: 12 KSLDDRQGEESQ-KGETSERETTATESGNESKSVEKEGGETQEKPKQPHVTYYNEEQYKQ 70 Query: 603 ----------KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVE 752 K ++DF++L +G G+FG V L R + + YAMK LKK ++R QVE Sbjct: 71 FIAQARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVE 130 Query: 753 HVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFY 932 H ER +L+ V +I++++ +FQD + +++IM+Y+ GG++ +LL + AKFY Sbjct: 131 HTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFY 190 Query: 933 IAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTP 1112 AE LA+E +H + I+RD+KP+N FG K + + PDY Sbjct: 191 AAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDY-- 248 Query: 1113 GKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYG 1292 +A V T K Y Sbjct: 249 -------------------------------------IAPEVVST-----------KPYN 260 Query: 1293 MECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKL 1472 DWWS G ++YEML GY PFY + M T KI+N + L+FP + + KDL+S+L Sbjct: 261 KSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILN--AELRFP--PFFNEDVKDLLSRL 316 Query: 1473 LC-NVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEV-NGELDTQNFEKFE 1634 + ++ QRLG G ++K H WF+ V WEKL ++ + P + G+ DT F+K+ Sbjct: 317 ITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYP 376 Query: 1635 E 1637 E Sbjct: 377 E 377
>P11792:SCH9_YEAST Serine/threonine-protein kinase SCH9 - Saccharomyces cerevisiae| (Baker's yeast) Length = 824 Score = 189 bits (480), Expect = 4e-47 Identities = 125/401 (31%), Positives = 200/401 (49%), Gaps = 11/401 (2%) Frame = +3 Query: 582 YMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVK 761 Y + ++ G +DFE+L ++G+G FG+V ++K ++ +YAMK L K ++++ ++ H Sbjct: 399 YKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTI 458 Query: 762 AERNLL---AEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFY 932 ERN+L A S +IV L +SFQ LYL+ +Y+ GG++ L ++ +ED AKFY Sbjct: 459 GERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFY 518 Query: 933 IAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTP 1112 IAE VLA+E +H ++ ++RD+KP+N FGL K Sbjct: 519 IAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSK----------------- 561 Query: 1113 GKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLL-KKGY 1289 L D T+ + GT +Y+APE+LL + GY Sbjct: 562 ----ADLKDRTN----------------------------TFCGTTEYLAPELLLDETGY 589 Query: 1290 GMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISK 1469 D+WSLG +++EM G+ PF++E+ +KI + +KFP + LS E + + Sbjct: 590 TKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGK--VKFPRDV-LSQEGRSFVKG 646 Query: 1470 LL-CNVEQRLGT-KGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKFEE 1637 LL N + RLG E++AH +F + WE L Q K F P + E DT NF+ E Sbjct: 647 LLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDP-EF 705 Query: 1638 TGAQVQSSSKAGPW---RKMLPSKDANFVGYTYKNFEIVND 1751 T A +K P + P+ A F G+T+ + +++ Sbjct: 706 TTASTSYMNKHQPMMTATPLSPAMQAKFAGFTFVDESAIDE 746
>Q7TPS0:KS6A6_MOUSE Ribosomal protein S6 kinase alpha-6 - Mus musculus (Mouse)| Length = 764 Score = 189 bits (479), Expect = 5e-47 Identities = 132/437 (30%), Positives = 214/437 (48%), Gaps = 6/437 (1%) Frame = +3 Query: 333 PAVPASHGKDPGKPPVDDAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKL 512 P P D V + SS+ Q V K + + K + D K M++ + Sbjct: 3 PFAPVEDPWDQEDMEVFGSTSSSEPQVVFTMKNAATVMREHERKEVNDLK----MVDEPM 58 Query: 513 QDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT-- 686 ++ E + + ++K E T++++ K F+LL ++G+G+FG+V L R+KT Sbjct: 59 EEGEPVSCRREELVK--EVPITQHVKEGYEKADPAQFDLLKVLGQGSFGKVFLVRKKTGP 116 Query: 687 -SRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYL 863 + +YAMK L+K+ + R +V K ER++L EV+ +IVKL+Y+FQ + LYLI+++L Sbjct: 117 DAGQLYAMKVLRKASLKVRDRVR-TKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFL 175 Query: 864 PGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXX 1043 GGD+ T L ++ TE++ KFY+AE LA++ +H+ ++RD+KP+N Sbjct: 176 RGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHRLGIVYRDLKPENILLDEIGHIKLT 235 Query: 1044 XFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRM 1223 FGL K + QE+ Sbjct: 236 DFGLSK-------------------------------------ESVDQEK---------- 248 Query: 1224 LAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNW 1403 AYS GT +Y+APEV+ ++ + DWWS G +M+EML G PF +D T I+ Sbjct: 249 KAYSFCGTVEYMAPEVVNRRAHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMIL-- 306 Query: 1404 RSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGAHEIKAHTWFRGVQWEKLY--QMK 1574 ++ L P+ LS+E + L+ L N RLG++G E+K H +F + W KLY +++ Sbjct: 307 KAKLGMPQ--FLSAEAQSLLRMLFKRNPANRLGSEGVEEVKRHAFFASIDWNKLYKREVQ 364 Query: 1575 AAFVPEVNGELDTQNFE 1625 F P DT F+ Sbjct: 365 PPFRPASGKPDDTFCFD 381 Score = 94.7 bits (234), Expect = 1e-18 Identities = 80/312 (25%), Positives = 131/312 (41%), Gaps = 5/312 (1%) Frame = +3 Query: 615 EDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS 794 E +EL IG G++ + C S +A+K + K+ +R E ++ L+ Sbjct: 444 EAYELKEDIGIGSYSVCKRCIHSASNVEFAVKIIDKN---KRDPSEEIEI---LMRYGQH 497 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 I+ L F D +++YL+ + + GG+++ +++K +E EA + +E +H Sbjct: 498 PNIISLKEVFDDGKYVYLVTDLMKGGELLDRILKKKCFSEQEASNVLYVITKTVECLHSQ 557 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFP-NLNEPDYTPGKGAKPLPDNTSR 1151 +HRD+KP N +D S P ++ D+ AK L Sbjct: 558 GVVHRDLKPSNILY----------------MDESAHPDSIKICDF---GFAKQLRGENGL 598 Query: 1152 LTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 1331 L P T +++APEVL ++GY CD WSLG ++Y Sbjct: 599 LLTPCY-------------------------TANFVAPEVLTQQGYDAACDIWSLGVLLY 633 Query: 1332 EMLVGYPPFY---SEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLG 1499 ML GY PF ++ P +I N R L +S KDL+S +L + QR Sbjct: 634 TMLAGYTPFSNGPNDTPEEILLRIGNGRFSLSGGIWDNISRGAKDLLSHMLHMDPHQRY- 692 Query: 1500 TKGAHEIKAHTW 1535 A ++ H W Sbjct: 693 --TAEQVLKHPW 702
>P25341:KIN82_YEAST Probable serine/threonine-protein kinase KIN82 - Saccharomyces| cerevisiae (Baker's yeast) Length = 720 Score = 188 bits (478), Expect = 7e-47 Identities = 114/332 (34%), Positives = 172/332 (51%), Gaps = 4/332 (1%) Frame = +3 Query: 615 EDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS 794 + FE + ++G+G G+V L RE+ + ++A+K L K EM++R +++ V E+ +LA D Sbjct: 322 QSFEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDH 381 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDT--LTEDEAKFYIAETVLAIESIH 968 +IV LY+SFQ ++LYL MEY GG+ L + + + E++AKFY +E V A+E +H Sbjct: 382 PFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLH 441 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 +I+RD+KP+N F L S P + + Y K Sbjct: 442 LLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKIC-------- 493 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 S RT S VGT +Y+APEV+ G+ DWW+LG ++ Sbjct: 494 -----SDGFRTN----------------SFVGTEEYLAPEVIRGNGHTAAVDWWTLGILI 532 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTK 1505 YEML G PF ++ T I+ +KFP + ++S KDLI KLL N +RLG+K Sbjct: 533 YEMLFGCTPFKGDNSNETFSNILT--KDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSK 590 Query: 1506 -GAHEIKAHTWFRGVQWEKLYQMKAAFVPEVN 1598 GA +IK H +F+ VQW L +P +N Sbjct: 591 SGAADIKRHPFFKKVQWSFLRNQDPPLIPALN 622
>P51812:KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 - Homo sapiens (Human)| Length = 740 Score = 188 bits (477), Expect = 9e-47 Identities = 137/429 (31%), Positives = 209/429 (48%), Gaps = 11/429 (2%) Frame = +3 Query: 504 RKLQDAEVPAEEQNNILKHLEKKE---TEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLC 674 +++ D + EE N + + KE T +++ K FELL ++G+G+FG+V L Sbjct: 26 QQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLV 85 Query: 675 RE---KTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLY 845 ++ +R +YAMK LKK+ + R +V K ER++L EV+ +IVKL+Y+FQ + LY Sbjct: 86 KKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEVNHPFIVKLHYAFQTEGKLY 144 Query: 846 LIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXX 1025 LI+++L GGD+ T L ++ TE++ KFY+AE LA++ +H I+RD+KP+N Sbjct: 145 LILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEE 204 Query: 1026 XXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHW 1205 FGL K E + H Sbjct: 205 GHIKLTDFGLSK------------------------------------------ESIDHE 222 Query: 1206 QKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTC 1385 +K AYS GT +Y+APEV+ ++G+ DWWS G +M+EML G PF +D T Sbjct: 223 KK-----AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETM 277 Query: 1386 RKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWE 1556 I+ ++ L P+ LS E + L+ L N RLG G EIK H++F + W Sbjct: 278 TMIL--KAKLGMPQ--FLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWN 333 Query: 1557 KLY--QMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYK 1730 KLY ++ F P DT F+ E A+ S P PS +A+ + + Sbjct: 334 KLYRREIHPPFKPATGRPEDTFYFD--PEFTAKTPKDSPGIP-----PSANAHQLFRGFS 386 Query: 1731 NFEIVNDDE 1757 I +DDE Sbjct: 387 FVAITSDDE 395 Score = 99.0 bits (245), Expect = 7e-20 Identities = 87/343 (25%), Positives = 147/343 (42%), Gaps = 7/343 (2%) Frame = +3 Query: 588 RLQRHKMGVED-FELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKA 764 +L R+ + D +E+ IG G++ + C K + +A+K + KS +R E ++ Sbjct: 410 QLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI 466 Query: 765 ERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 LL I+ L + D +++Y++ E + GG+++ ++R+ +E EA + Sbjct: 467 ---LLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTI 523 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 +E +H +HRD+KP N +S N ++ D+ A Sbjct: 524 TKTVEYLHAQGVVHRDLKPSNILYVD---------------ESGNPESIRICDFG---FA 565 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 K L L P T +++APEVL ++GY CD Sbjct: 566 KQLRAENGLLMTPCY-------------------------TANFVAPEVLKRQGYDAACD 600 Query: 1305 WWSLGAIMYEMLVGYPPFYS---EDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL 1475 WSLG ++Y ML GY PF + + P +I + + L +S KDL+SK+L Sbjct: 601 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML 660 Query: 1476 -CNVEQRLGTKGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEV 1595 + QRL A + H W V W++L YQ+ P + Sbjct: 661 HVDPHQRL---TAALVLRHPWI--VHWDQLPQYQLNRQDAPHL 698
>P06245:KAPB_YEAST cAMP-dependent protein kinase type 2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 380 Score = 188 bits (477), Expect = 9e-47 Identities = 109/355 (30%), Positives = 176/355 (49%), Gaps = 6/355 (1%) Frame = +3 Query: 591 LQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAER 770 + + K + DF+++ +G G+FG V L R + YA+K LKK ++++ QVEH ER Sbjct: 60 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDER 119 Query: 771 NLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVL 950 +L V+ ++++++ +FQD ++++M+Y+ GG++ +LL + AKFY AE +L Sbjct: 120 RMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVIL 179 Query: 951 AIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKP 1130 A+E +H HN I+RD+KP+N FG K + + + PDY Sbjct: 180 ALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDY-------- 231 Query: 1131 LPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWW 1310 IAPEV+ K Y DWW Sbjct: 232 ------------------------------------------IAPEVITTKPYNKSVDWW 249 Query: 1311 SLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVE 1487 SLG ++YEML GY PFY PM T KI+ + + +P + DL+SKL+ ++ Sbjct: 250 SLGVLIYEMLAGYTPFYDTTPMKTYEKIL--QGKVVYP--PYFHPDVVDLLSKLITADLT 305 Query: 1488 QRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEV-NGELDTQNFEKFEE 1637 +R+G G+ +IKAH WF V WE+L ++ + P + +G DT F+++ E Sbjct: 306 RRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPE 360
>P18654:KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 - Mus musculus (Mouse)| Length = 740 Score = 187 bits (474), Expect = 2e-46 Identities = 137/445 (30%), Positives = 216/445 (48%), Gaps = 9/445 (2%) Frame = +3 Query: 450 KTQMKSLQDRKER-RWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFE 626 K ++S D E + +++ + + E+ + + +K + T +++ K FE Sbjct: 12 KMAVESPSDSAENGQQIMDEPMGEEEINPQTEEGSIKEIAI--THHVKEGHEKADPSQFE 69 Query: 627 LLTIIGRGAFGEVRLCRE---KTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA 797 LL ++G+G+FG+V L ++ +R +YAMK LKK+ + R +V K ER++L EV+ Sbjct: 70 LLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVEVNHP 128 Query: 798 YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHN 977 +IVKL+Y+FQ + LYLI+++L GGD+ T L ++ TE++ KFY+AE LA++ +H Sbjct: 129 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG 188 Query: 978 YIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLT 1157 I+RD+KP+N FGL K Sbjct: 189 IIYRDLKPENILLDEEGHIKLTDFGLSK-------------------------------- 216 Query: 1158 NPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEM 1337 E + H +K AYS GT +Y+APEV+ ++G+ DWWS G +M+EM Sbjct: 217 ----------ESIDHEKK-----AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEM 261 Query: 1338 LVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT--KG 1508 L G PF +D T I+ ++ L P+ LS E + L+ L N RLG G Sbjct: 262 LTGTLPFQGKDRKETMTMIL--KAKLGMPQ--FLSPEAQSLLRMLFKRNPANRLGAGPDG 317 Query: 1509 AHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWR 1682 EIK H++F + W KLY ++ F P DT F+ E A+ S P Sbjct: 318 VEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFD--PEFTAKTPKDSPGIP-- 373 Query: 1683 KMLPSKDANFVGYTYKNFEIVNDDE 1757 PS +A+ + + I +DDE Sbjct: 374 ---PSANAHQLFRGFSFVAITSDDE 395 Score = 99.0 bits (245), Expect = 7e-20 Identities = 87/343 (25%), Positives = 147/343 (42%), Gaps = 7/343 (2%) Frame = +3 Query: 588 RLQRHKMGVED-FELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKA 764 +L R+ + D +E+ IG G++ + C K + +A+K + KS +R E ++ Sbjct: 410 QLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI 466 Query: 765 ERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 LL I+ L + D +++Y++ E + GG+++ ++R+ +E EA + Sbjct: 467 ---LLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTI 523 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 +E +H +HRD+KP N +S N ++ D+ A Sbjct: 524 TKTVEYLHAQGVVHRDLKPSNILYVD---------------ESGNPESIRICDFG---FA 565 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 K L L P T +++APEVL ++GY CD Sbjct: 566 KQLRAENGLLMTPCY-------------------------TANFVAPEVLKRQGYDAACD 600 Query: 1305 WWSLGAIMYEMLVGYPPFYS---EDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL 1475 WSLG ++Y ML GY PF + + P +I + + L +S KDL+SK+L Sbjct: 601 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML 660 Query: 1476 -CNVEQRLGTKGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEV 1595 + QRL A + H W V W++L YQ+ P + Sbjct: 661 HVDPHQRL---TAALVLRHPWI--VHWDQLPQYQLNRQDAPHL 698
>Q15418:KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 - Homo sapiens (Human)| Length = 735 Score = 186 bits (471), Expect = 4e-46 Identities = 135/424 (31%), Positives = 211/424 (49%), Gaps = 10/424 (2%) Frame = +3 Query: 513 QDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT-- 686 ++A + + +LK + T +++ K FELL ++G+G+FG+V L R+ T Sbjct: 28 EEAGLQPSKDEGVLKEISI--THHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRP 85 Query: 687 -SRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYL 863 S +YAMK LKK+ + R +V K ER++LA+V+ ++VKL+Y+FQ + LYLI+++L Sbjct: 86 DSGHLYAMKVLKKATLKVRDRVR-TKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFL 144 Query: 864 PGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXX 1043 GGD+ T L ++ TE++ KFY+AE L ++ +H I+RD+KP+N Sbjct: 145 RGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLT 204 Query: 1044 XFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRM 1223 FGL K E + H +K Sbjct: 205 DFGLSK------------------------------------------EAIDHEKK---- 218 Query: 1224 LAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNW 1403 AYS GT +Y+APEV+ ++G+ DWWS G +M+EML G PF +D T I+ Sbjct: 219 -AYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL-- 275 Query: 1404 RSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--Q 1568 ++ L P+ LS+E + L+ L N RLG+ GA EIK H ++ + W KLY + Sbjct: 276 KAKLGMPQ--FLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRRE 333 Query: 1569 MKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDAN--FVGYTYKNFEI 1742 +K F P V DT F+ E ++ S P PS A+ F G+++ + Sbjct: 334 IKPPFKPAVAQPDDTFYFD--TEFTSRTPKDSPGIP-----PSAGAHQLFRGFSFVATGL 386 Query: 1743 VNDD 1754 + DD Sbjct: 387 MEDD 390 Score = 100 bits (248), Expect = 3e-20 Identities = 85/314 (27%), Positives = 136/314 (43%), Gaps = 4/314 (1%) Frame = +3 Query: 639 IGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYY 818 IG G++ E + C K + YA+K + KS +R E ++ LL I+ L Sbjct: 424 IGVGSYSECKRCVHKATNMEYAVKVIDKS---KRDPSEEIEI---LLRYGQHPNIITLKD 477 Query: 819 SFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIK 998 + D + +YL+ E + GG+++ ++R+ +E EA F + +E +H +HRD+K Sbjct: 478 VYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLK 537 Query: 999 PDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKR 1178 P N +D S P R+ + K+ Sbjct: 538 PSNILY----------------VDESGNP------------------ECLRICDFGFAKQ 563 Query: 1179 TQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPF 1358 + E L + T +++APEVL ++GY CD WSLG ++Y ML GY PF Sbjct: 564 LRAE---------NGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPF 614 Query: 1359 Y---SEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGAHEIKA 1526 S+ P +I + + L +S KDL+SK+L + QRL K ++ Sbjct: 615 ANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAK---QVLQ 671 Query: 1527 HTWFRGVQWEKLYQ 1568 H W Q +KL Q Sbjct: 672 HPWV--TQKDKLPQ 683
>P21137:KAPC_CAEEL cAMP-dependent protein kinase catalytic subunit - Caenorhabditis| elegans Length = 404 Score = 186 bits (471), Expect = 4e-46 Identities = 115/392 (29%), Positives = 185/392 (47%), Gaps = 20/392 (5%) Frame = +3 Query: 507 KLQDAEVPAEEQNNIL-KHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREK 683 KL + P E+ L K E + + ++ ++DF+ + +G G+FG V L + K Sbjct: 42 KLSILDDPVEDFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHK 101 Query: 684 TSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYL 863 S + YAMK L K ++++ QVEH E+ +L +D ++V + +SF+D+ LY+++E++ Sbjct: 102 QSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFI 161 Query: 864 PGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXX 1043 GG+M + L R +E ++FY A+ VLA E +H + I+RD+KP+N Sbjct: 162 SGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKIT 221 Query: 1044 XFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRM 1223 FG K + + P+Y Sbjct: 222 DFGFAKRVKGRTWTLCGTPEY--------------------------------------- 242 Query: 1224 LAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNW 1403 +APE++L KGY DWW+LG ++YEM GYPPF+++ P+ KIV+ Sbjct: 243 -----------LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 291 Query: 1404 RSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK 1574 + +KFP + S+E KDL+ LL ++ +R G G +IK H WF W +YQ K Sbjct: 292 K--VKFP--SHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKK 347 Query: 1575 ----------------AAFVPEVNGELDTQNF 1622 A P V+G DT++F Sbjct: 348 ITPPSFSKGESNGRLFEALYPRVDGPADTRHF 379
>Q17941:AKT1_CAEEL Serine/threonine-protein kinase akt-1 - Caenorhabditis elegans| Length = 541 Score = 185 bits (469), Expect = 7e-46 Identities = 121/388 (31%), Positives = 194/388 (50%), Gaps = 8/388 (2%) Frame = +3 Query: 594 QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN 773 +R K+ +EDF+ L ++G+G FG+V LC+EK ++ +YA+K LKK ++ R +V H E Sbjct: 184 KRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENR 243 Query: 774 LLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLA 953 +L ++ +L YSFQ+ +L +M++ GG++ T + + T +E A+FY AE VLA Sbjct: 244 VLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLA 303 Query: 954 IESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 + +H+ + ++RD+K +N FGLCK Sbjct: 304 LGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCK------------------------ 339 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 E++S K + GTP+Y+APEVL YG DWW Sbjct: 340 ------------------EEISFGDKTS-----TFCGTPEYLAPEVLDDHDYGRCVDWWG 376 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQ 1490 +G +MYEM+ G PFYS+D I+ L+FP +KLS E + L++ LL + Q Sbjct: 377 VGVVMYEMMCGRLPFYSKDHNKLFELIM--AGDLRFP--SKLSQEARTLLTGLLVKDPTQ 432 Query: 1491 RL--GTKGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFE-KFEETGAQVQ 1655 RL G + A EI +FR V WE Y +++ + P V E DT F+ +F Q+ Sbjct: 433 RLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYFDNEFTSQPVQLT 492 Query: 1656 SSSKAGPWRKMLPSKD--ANFVGYTYKN 1733 S++G + ++ +NF +++ N Sbjct: 493 PPSRSGALATVDEQEEMQSNFTQFSFHN 520
>P18652:KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha - Gallus gallus (Chicken)| Length = 752 Score = 184 bits (467), Expect = 1e-45 Identities = 132/405 (32%), Positives = 203/405 (50%), Gaps = 10/405 (2%) Frame = +3 Query: 576 TEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT---SRSVYAMKKLKKSEMLRRGQ 746 T +++ K FELL ++G+G+FG+V L R+ T S +YAMK LKK+ + R + Sbjct: 65 THHVKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDR 124 Query: 747 VEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAK 926 V K ER++LA+V+ ++VKL+Y+FQ + LYLI+++L GGD+ T L ++ TE++ K Sbjct: 125 VR-TKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVK 183 Query: 927 FYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDY 1106 FY+AE L ++ +H I+RD+KP+N FGL K Sbjct: 184 FYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK--------------- 228 Query: 1107 TPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKG 1286 E + H +K AYS GT +Y+APEV+ ++G Sbjct: 229 ---------------------------EAIDHEKK-----AYSFCGTVEYMAPEVVNRQG 256 Query: 1287 YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLIS 1466 + DWWS G +M+EML G PF +D T I+ ++ L P+ LS+E + L+ Sbjct: 257 HSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL--KAKLGMPQ--FLSAEAQSLLR 312 Query: 1467 KLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKF 1631 L N RLG+ GA EIK H ++ + W KLY ++K F P V DT F+ Sbjct: 313 ALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTFYFD-- 370 Query: 1632 EETGAQVQSSSKAGPWRKMLPSKDAN--FVGYTYKNFEIVNDDEV 1760 E ++ S P PS A+ F G+++ ++ D +V Sbjct: 371 TEFTSRTPKDSPGIP-----PSAGAHQLFRGFSFVATGLMEDSKV 410 Score = 95.5 bits (236), Expect = 8e-19 Identities = 86/352 (24%), Positives = 151/352 (42%), Gaps = 5/352 (1%) Frame = +3 Query: 495 MLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLC 674 M + K++ A+ P +++++ L K ++ + + + IG G++ + C Sbjct: 405 MEDSKVKPAQPPL---HSVVQQLHGKNIQFS---------DGYVVKEAIGVGSYSVCKRC 452 Query: 675 REKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIM 854 KT+ YA+K + KS +R E ++ LL I+ L + D +++YL+ Sbjct: 453 IHKTTNMEYAVKVIDKS---KRDPSEEIEI---LLRYGQHPNIITLKDVYDDGKYVYLVT 506 Query: 855 EYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXX 1034 E + GG+++ ++R+ +E EA + +E +H +HRD+KP N Sbjct: 507 ELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILY------ 560 Query: 1035 XXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKN 1214 +D S P + R+ + K+ + E Sbjct: 561 ----------VDESGNP------------------ESIRICDFGFAKQLRAE-------- 584 Query: 1215 RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKI 1394 L + T +++APEVL ++GY CD WSLG ++Y ML G PF + P T +I Sbjct: 585 -NGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPF-ANGPSDTPEEI 642 Query: 1395 VNWRSHLKFPEEA----KLSSETKDLISKLL-CNVEQRLGTKGAHEIKAHTW 1535 + KF +S KDL+SK+L + QRL K ++ H W Sbjct: 643 LTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAK---QVLQHPW 691
>Q63531:KS6A1_RAT Ribosomal protein S6 kinase alpha-1 - Rattus norvegicus (Rat)| Length = 735 Score = 183 bits (465), Expect = 2e-45 Identities = 135/424 (31%), Positives = 211/424 (49%), Gaps = 10/424 (2%) Frame = +3 Query: 513 QDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT-- 686 ++A + + ILK + T +++ K FELL ++G+G+FG+V L R+ T Sbjct: 28 EEAGLQPSKDEGILKEISI--THHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRP 85 Query: 687 -SRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYL 863 + +YAMK LKK+ + R +V K ER++LA+V+ ++VKL+Y+FQ + LYLI+++L Sbjct: 86 DNGHLYAMKVLKKATLKVRDRVR-TKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFL 144 Query: 864 PGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXX 1043 GGD+ T L ++ TE++ KFY+AE L ++ +H I+RD+KP+N Sbjct: 145 RGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLT 204 Query: 1044 XFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRM 1223 FGL K E + H +K Sbjct: 205 DFGLSK------------------------------------------EAIDHEKK---- 218 Query: 1224 LAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNW 1403 AYS GT +Y+APEV+ ++G+ DWWS G +M+EML G PF +D T I+ Sbjct: 219 -AYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL-- 275 Query: 1404 RSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--Q 1568 ++ L P+ LS+E + L+ L N RLG+ GA EIK H ++ + W KLY + Sbjct: 276 KAKLGMPQ--FLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRRE 333 Query: 1569 MKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDAN--FVGYTYKNFEI 1742 +K F P V DT F+ E ++ S P PS A+ F G+++ + Sbjct: 334 IKPPFKPAVAQPDDTFYFD--TEFTSRTPRDSPGIP-----PSAGAHQLFRGFSFVATGL 386 Query: 1743 VNDD 1754 + DD Sbjct: 387 MEDD 390 Score = 99.8 bits (247), Expect = 4e-20 Identities = 88/315 (27%), Positives = 134/315 (42%), Gaps = 5/315 (1%) Frame = +3 Query: 639 IGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYY 818 IG G++ + C K + YA+K + KS +R E ++ LL I+ L Sbjct: 424 IGVGSYSVCKRCVHKATNMEYAVKVIDKS---KRDPSEEIEI---LLRYGQHPNIITLKD 477 Query: 819 SFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIK 998 + D + +YL+ E + GG+++ ++R+ +E EA F + +E +H +HRD+K Sbjct: 478 VYDDSKHVYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTVEYLHSQGVVHRDLK 537 Query: 999 PDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKR 1178 P N +S N L D+ AK L L P Sbjct: 538 PSNILYVD---------------ESGNPECLRICDFG---FAKQLRAENGLLMTPCY--- 576 Query: 1179 TQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPF 1358 T +++APEVL ++GY CD WSLG ++Y ML GY PF Sbjct: 577 ----------------------TANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPF 614 Query: 1359 YSEDPMSTCRKIVNWRSHLKFPEEA----KLSSETKDLISKLL-CNVEQRLGTKGAHEIK 1523 + P T +I+ S KF +S KDL+SK+L + QRL K ++ Sbjct: 615 -ANGPSDTPEEILTRISSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAK---QVL 670 Query: 1524 AHTWFRGVQWEKLYQ 1568 H W Q +KL Q Sbjct: 671 QHPWI--TQKDKLPQ 683
>Q9Z0Z0:KGP1B_MOUSE cGMP-dependent protein kinase 1, beta isozyme - Mus musculus (Mouse)| Length = 686 Score = 183 bits (464), Expect = 3e-45 Identities = 110/360 (30%), Positives = 172/360 (47%), Gaps = 6/360 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRS-VYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 + DF ++ +G G FG V L + K+ S +AMK LKK ++ Q EH+++E+ ++ Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 S +IV+LY +F+D ++LY++ME GG++ T+L + + + +FY A V A +H Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 I+RD+KP+N FG K + G G K Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI---------------GFGKK------- 529 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 ++ GTP+Y+APE++L KG+ + D+WSLG +M Sbjct: 530 --------------------------TWTFCGTPEYVAPEIILNKGHDISADYWSLGILM 563 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT- 1502 YE+L G PPF DPM T I+ ++FP+ K++ +LI KL N +RLG Sbjct: 564 YELLTGSPPFSGPDPMKTYNIILRGIDMIEFPK--KIAKNAANLIKKLCRDNPSERLGNL 621 Query: 1503 -KGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAG 1673 G +I+ H WF G WE L + + +P V DT NF+ F E + +G Sbjct: 622 KNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEPPPDDNSG 681
>P14619:KGP1B_HUMAN cGMP-dependent protein kinase 1, beta isozyme - Homo sapiens (Human)| Length = 686 Score = 183 bits (464), Expect = 3e-45 Identities = 110/360 (30%), Positives = 172/360 (47%), Gaps = 6/360 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRS-VYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 + DF ++ +G G FG V L + K+ S +AMK LKK ++ Q EH+++E+ ++ Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 S +IV+LY +F+D ++LY++ME GG++ T+L + + + +FY A V A +H Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 I+RD+KP+N FG K + G G K Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI---------------GFGKK------- 529 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 ++ GTP+Y+APE++L KG+ + D+WSLG +M Sbjct: 530 --------------------------TWTFCGTPEYVAPEIILNKGHDISADYWSLGILM 563 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT- 1502 YE+L G PPF DPM T I+ ++FP+ K++ +LI KL N +RLG Sbjct: 564 YELLTGSPPFSGPDPMKTYNIILRGIDMIEFPK--KIAKNAANLIKKLCRDNPSERLGNL 621 Query: 1503 -KGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAG 1673 G +I+ H WF G WE L + + +P V DT NF+ F E + +G Sbjct: 622 KNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSG 681
>P21136:KGP1B_BOVIN cGMP-dependent protein kinase 1, beta isozyme - Bos taurus (Bovine)| Length = 686 Score = 183 bits (464), Expect = 3e-45 Identities = 110/360 (30%), Positives = 172/360 (47%), Gaps = 6/360 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRS-VYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 + DF ++ +G G FG V L + K+ S +AMK LKK ++ Q EH+++E+ ++ Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 S +IV+LY +F+D ++LY++ME GG++ T+L + + + +FY A V A +H Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 I+RD+KP+N FG K + G G K Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI---------------GFGKK------- 529 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 ++ GTP+Y+APE++L KG+ + D+WSLG +M Sbjct: 530 --------------------------TWTFCGTPEYVAPEIILNKGHDISADYWSLGILM 563 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT- 1502 YE+L G PPF DPM T I+ ++FP+ K++ +LI KL N +RLG Sbjct: 564 YELLTGSPPFSGPDPMKTYNIILRGIDMIEFPK--KIAKNAANLIKKLCRDNPSERLGNL 621 Query: 1503 -KGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAG 1673 G +I+ H WF G WE L + + +P V DT NF+ F E + +G Sbjct: 622 KNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSG 681
>Q13976:KGP1A_HUMAN cGMP-dependent protein kinase 1, alpha isozyme - Homo sapiens (Human)| Length = 671 Score = 183 bits (464), Expect = 3e-45 Identities = 110/360 (30%), Positives = 172/360 (47%), Gaps = 6/360 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRS-VYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 + DF ++ +G G FG V L + K+ S +AMK LKK ++ Q EH+++E+ ++ Sbjct: 357 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 416 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 S +IV+LY +F+D ++LY++ME GG++ T+L + + + +FY A V A +H Sbjct: 417 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 476 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 I+RD+KP+N FG K + G G K Sbjct: 477 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI---------------GFGKK------- 514 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 ++ GTP+Y+APE++L KG+ + D+WSLG +M Sbjct: 515 --------------------------TWTFCGTPEYVAPEIILNKGHDISADYWSLGILM 548 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT- 1502 YE+L G PPF DPM T I+ ++FP+ K++ +LI KL N +RLG Sbjct: 549 YELLTGSPPFSGPDPMKTYNIILRGIDMIEFPK--KIAKNAANLIKKLCRDNPSERLGNL 606 Query: 1503 -KGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAG 1673 G +I+ H WF G WE L + + +P V DT NF+ F E + +G Sbjct: 607 KNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSG 666
>P00516:KGP1A_BOVIN cGMP-dependent protein kinase 1, alpha isozyme - Bos taurus (Bovine)| Length = 671 Score = 183 bits (464), Expect = 3e-45 Identities = 110/360 (30%), Positives = 172/360 (47%), Gaps = 6/360 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRS-VYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 + DF ++ +G G FG V L + K+ S +AMK LKK ++ Q EH+++E+ ++ Sbjct: 357 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 416 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 S +IV+LY +F+D ++LY++ME GG++ T+L + + + +FY A V A +H Sbjct: 417 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 476 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 I+RD+KP+N FG K + G G K Sbjct: 477 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI---------------GFGKK------- 514 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 ++ GTP+Y+APE++L KG+ + D+WSLG +M Sbjct: 515 --------------------------TWTFCGTPEYVAPEIILNKGHDISADYWSLGILM 548 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT- 1502 YE+L G PPF DPM T I+ ++FP+ K++ +LI KL N +RLG Sbjct: 549 YELLTGSPPFSGPDPMKTYNIILRGIDMIEFPK--KIAKNAANLIKKLCRDNPSERLGNL 606 Query: 1503 -KGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAG 1673 G +I+ H WF G WE L + + +P V DT NF+ F E + +G Sbjct: 607 KNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSG 666
>O77676:KGP1A_RABIT cGMP-dependent protein kinase 1, alpha isozyme - Oryctolagus| cuniculus (Rabbit) Length = 671 Score = 182 bits (462), Expect = 5e-45 Identities = 110/360 (30%), Positives = 172/360 (47%), Gaps = 6/360 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRS-VYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 + DF ++ +G G FG V L + K+ S +AMK LKK ++ Q EH+++E+ ++ Sbjct: 357 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 416 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 S +IV+LY +F+D ++LY++ME GG++ T+L + + + +FY A V A +H Sbjct: 417 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 476 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 I+RD+KP+N FG K + G G K Sbjct: 477 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI---------------GFGKK------- 514 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 ++ GTP+Y+APE++L KG+ + D+WSLG +M Sbjct: 515 --------------------------TWTFCGTPEYVAPEIILNKGHDISADYWSLGILM 548 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT- 1502 YE+L G PPF DPM T I+ ++FP+ K++ +LI KL N +RLG Sbjct: 549 YELLTGSPPFSGPDPMKTYNIILRGIDMIEFPK--KIAKNAANLIKKLCRDNPSERLGNL 606 Query: 1503 -KGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAG 1673 G +I+ H WF G WE L + + +P V DT NF+ F E + +G Sbjct: 607 KNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDGFPEDNDEPPPDDNSG 666
>Q9HBY8:SGK2_HUMAN Serine/threonine-protein kinase Sgk2 - Homo sapiens (Human)| Length = 427 Score = 182 bits (461), Expect = 6e-45 Identities = 126/376 (33%), Positives = 186/376 (49%), Gaps = 6/376 (1%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDS 794 DF+ L +IG+G +G+V L + K+ + YA+K L+K +L++ + H+ AER+ LL V Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V L YSFQ E LY +++Y+ GG++ L R+ E A+FY AE AI +H Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 N I+RD+KP+N FGLCK +G +P D TS Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCK------------------EGVEP-EDTTS-- 252 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 + GTP+Y+APEVL K+ Y DWW LGA++YE Sbjct: 253 --------------------------TFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYE 286 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGA 1511 ML G PPFYS+D I++ L+ P +++ DL+ LL + QRLG+K Sbjct: 287 MLHGLPPFYSQDVSQMYENILH--QPLQIPGGRTVAA--CDLLQSLLHKDQRQRLGSKAD 342 Query: 1512 H-EIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWR 1682 EIK H +F + W+ LY ++ F P V G D ++F+ E T V S P Sbjct: 343 FLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDP-EFTQEAVSKSIGCTPDT 401 Query: 1683 KMLPS-KDANFVGYTY 1727 S + F+G++Y Sbjct: 402 VASSSGASSAFLGFSY 417
>Q9WUT3:KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 - Mus musculus (Mouse)| Length = 733 Score = 182 bits (461), Expect = 6e-45 Identities = 133/416 (31%), Positives = 207/416 (49%), Gaps = 11/416 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAM 707 E+ I+K ++ + +++ K FELL ++G+G++G+V L R+ T +YAM Sbjct: 33 EEEGIVKEIDI--SNHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAM 90 Query: 708 KKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTL 887 K LKK+ + R +V K ER++LAEV+ +IVKL+Y+FQ + LYLI+++L GGD+ T Sbjct: 91 KVLKKATLKVRDRVRS-KMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTR 149 Query: 888 LMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPL 1067 L ++ TE++ KFY+AE LA++ +H I+RD+KP+N FGL Sbjct: 150 LSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGL---- 205 Query: 1068 DSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGT 1247 +K D+ R AYS GT Sbjct: 206 ------------------SKEATDHDKR-------------------------AYSFCGT 222 Query: 1248 PDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE 1427 +Y+APEV+ ++G+ DWWS G +M+EML G PF +D T I+ ++ L P+ Sbjct: 223 IEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALIL--KAKLGMPQ 280 Query: 1428 EAKLSSETKDLISKLL----CNVEQRLGTKGAHEIKAHTWFRGVQWEKLY--QMKAAFVP 1589 LS+E + L+ L CN G G EIK H +F + W KLY ++K F P Sbjct: 281 --FLSAEAQSLLRALFKRNPCN-RLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKP 337 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDAN--FVGYTYKNFEIVND 1751 V DT +F+ E A+ + S P PS +A+ F G+++ +V + Sbjct: 338 AVGRPEDTFHFD--PEFTARTPTDSPGVP-----PSANAHHLFRGFSFVASSLVQE 386 Score = 97.8 bits (242), Expect = 2e-19 Identities = 82/340 (24%), Positives = 147/340 (43%), Gaps = 4/340 (1%) Frame = +3 Query: 615 EDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS 794 + +E+ IG G++ + C K + + YA+K + KS +R E ++ LL Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKS---KRDPSEEIEI---LLRYGQH 466 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 I+ L + D +++YL+ME + GG+++ ++R+ +E EA + ++ +H Sbjct: 467 PNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQ 526 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 +HRD+KP N +D S P + R+ Sbjct: 527 GVVHRDLKPSNILY----------------MDESGNP------------------ESIRI 552 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 + K+ + E L + T +++APEVL ++GY CD WSLG ++Y Sbjct: 553 CDFGFAKQLRAE---------NGLLMTPCYTANFVAPEVLKRQGYDAACDVWSLGILLYT 603 Query: 1335 MLVGYPPFYS---EDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT 1502 ML G+ PF + + P +I + + L +S KD++SK+L + +QRL Sbjct: 604 MLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQRL-- 661 Query: 1503 KGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNF 1622 A ++ H W ++ Q+ V V G + F Sbjct: 662 -TAVQVLKHPWIVNREYLSQNQLSRQDVHLVKGAMAATYF 700
>Q9WUA6:AKT3_MOUSE RAC-gamma serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 479 Score = 181 bits (460), Expect = 8e-45 Identities = 127/399 (31%), Positives = 184/399 (46%), Gaps = 5/399 (1%) Frame = +3 Query: 468 LQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGR 647 LQ ++E R Q + EE + H ++K + DF+ L ++G+ Sbjct: 109 LQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKT------------MNDFDYLKLLGK 156 Query: 648 GAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQ 827 G FG+V L REK S YAMK LKK ++ + +V H E +L ++ L YSFQ Sbjct: 157 GTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQ 216 Query: 828 DDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDN 1007 + L +MEY+ GG++ L R+ +ED +FY AE V A++ +H ++RD+K +N Sbjct: 217 TKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLEN 276 Query: 1008 XXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQ 1187 FGLCK +T+ + K Sbjct: 277 LMLDKDGHIKITDFGLCK----------------------------EGITDAATMK---- 304 Query: 1188 EQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSE 1367 + GTP+Y+APEVL YG DWW LG +MYEM+ G PFY++ Sbjct: 305 ---------------TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ 349 Query: 1368 DPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWF 1538 D I+ +KFP LSS+ K L+S LL + +RL G A EI H++F Sbjct: 350 DHEKLFELIL--MEDIKFPR--TLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFF 405 Query: 1539 RGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQ 1649 GV W+ +Y K F P+V E DT+ F+ EE AQ Sbjct: 406 SGVNWQDVYDKKLVPPFKPQVTSETDTRYFD--EEFTAQ 442
>Q9Y243:AKT3_HUMAN RAC-gamma serine/threonine-protein kinase - Homo sapiens (Human)| Length = 479 Score = 181 bits (460), Expect = 8e-45 Identities = 127/399 (31%), Positives = 184/399 (46%), Gaps = 5/399 (1%) Frame = +3 Query: 468 LQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGR 647 LQ ++E R Q + EE + H ++K + DF+ L ++G+ Sbjct: 109 LQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKT------------MNDFDYLKLLGK 156 Query: 648 GAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQ 827 G FG+V L REK S YAMK LKK ++ + +V H E +L ++ L YSFQ Sbjct: 157 GTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQ 216 Query: 828 DDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDN 1007 + L +MEY+ GG++ L R+ +ED +FY AE V A++ +H ++RD+K +N Sbjct: 217 TKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLEN 276 Query: 1008 XXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQ 1187 FGLCK +T+ + K Sbjct: 277 LMLDKDGHIKITDFGLCK----------------------------EGITDAATMK---- 304 Query: 1188 EQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSE 1367 + GTP+Y+APEVL YG DWW LG +MYEM+ G PFY++ Sbjct: 305 ---------------TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ 349 Query: 1368 DPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWF 1538 D I+ +KFP LSS+ K L+S LL + +RL G A EI H++F Sbjct: 350 DHEKLFELIL--MEDIKFPR--TLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFF 405 Query: 1539 RGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQ 1649 GV W+ +Y K F P+V E DT+ F+ EE AQ Sbjct: 406 SGVNWQDVYDKKLVPPFKPQVTSETDTRYFD--EEFTAQ 442
>P05986:KAPC_YEAST cAMP-dependent protein kinase type 3 - Saccharomyces cerevisiae| (Baker's yeast) Length = 398 Score = 179 bits (455), Expect = 3e-44 Identities = 111/365 (30%), Positives = 173/365 (47%), Gaps = 6/365 (1%) Frame = +3 Query: 561 LEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRR 740 L KK R K + DF++L +G G+FG V L R + YA+K LKK +++ Sbjct: 68 LVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKL 127 Query: 741 GQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDE 920 QVEH ER +L+ V +I++++ +FQD + ++++M+Y+ GG++ +LL + Sbjct: 128 KQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPV 187 Query: 921 AKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEP 1100 AKFY AE LA+E +H + I+RD+KP+N FG K + + P Sbjct: 188 AKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTP 247 Query: 1101 DYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLK 1280 DY +A V T Sbjct: 248 DY---------------------------------------IAPEVVST----------- 257 Query: 1281 KGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDL 1460 K Y DWWS G ++YEML GY PFY+ + M T I+N + LKFP + +DL Sbjct: 258 KPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILN--AELKFP--PFFHPDAQDL 313 Query: 1461 ISKLLC-NVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEV-NGELDTQNF 1622 + KL+ ++ +RLG G+ ++K H WF V WEKL ++ + P + G+ DT F Sbjct: 314 LKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQF 373 Query: 1623 EKFEE 1637 +++ E Sbjct: 374 DRYPE 378
>Q63484:AKT3_RAT RAC-gamma serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 479 Score = 179 bits (455), Expect = 3e-44 Identities = 126/399 (31%), Positives = 183/399 (45%), Gaps = 5/399 (1%) Frame = +3 Query: 468 LQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGR 647 LQ ++E R Q + EE + H ++K + DF+ L ++G+ Sbjct: 109 LQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKT------------MNDFDYLKLLGK 156 Query: 648 GAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQ 827 G FG+V L REK S YAMK LKK ++ + +V H E +L ++ L YSFQ Sbjct: 157 GTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQ 216 Query: 828 DDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDN 1007 + L +MEY+ GG++ L R+ +ED +FY AE V A++ +H ++RD+K +N Sbjct: 217 TKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLEN 276 Query: 1008 XXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQ 1187 FGLCK +T+ + K Sbjct: 277 LMLDKDGHIKITDFGLCK----------------------------EGITDAATMK---- 304 Query: 1188 EQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSE 1367 + GTP+Y+APEVL YG DWW LG +MYEM+ G PFY++ Sbjct: 305 ---------------TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ 349 Query: 1368 DPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWF 1538 D I+ +KFP LSS+ K L+S LL + +RL G EI H++F Sbjct: 350 DHEKLFELIL--MEDIKFPR--TLSSDAKSLLSGLLIKDPNKRLGGGPDDPKEIMRHSFF 405 Query: 1539 RGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQ 1649 GV W+ +Y K F P+V E DT+ F+ EE AQ Sbjct: 406 SGVNWQDVYDKKLVPPFKPQVTSETDTRYFD--EEFTAQ 442
>P10666:KS6AB_XENLA Ribosomal protein S6 kinase 2 beta - Xenopus laevis (African clawed| frog) Length = 629 Score = 179 bits (453), Expect = 5e-44 Identities = 118/358 (32%), Positives = 182/358 (50%), Gaps = 8/358 (2%) Frame = +3 Query: 576 TEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT---SRSVYAMKKLKKSEMLRRGQ 746 T +++ K F LL ++G+G+FG+V L R+ T + +YAMK LKK+ + R + Sbjct: 47 THHVKEGAEKADQSHFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDR 106 Query: 747 VEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAK 926 V K ER++LA+V ++V+L+Y+FQ + LYLI+++L GGD+ T L ++ TE++ K Sbjct: 107 VR-TKMERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVK 165 Query: 927 FYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDY 1106 FY+AE L ++ +H I+RD+KP+N FGL K Sbjct: 166 FYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK--------------- 210 Query: 1107 TPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKG 1286 E + H +K AYS GT +Y+APEV+ ++G Sbjct: 211 ---------------------------EAIDHEKK-----AYSFCGTVEYMAPEVVNRQG 238 Query: 1287 YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLIS 1466 + DWWS G +M+EML G PF +D T I+ ++ L P+ LS+E + L+ Sbjct: 239 HSHGADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL--KAKLGMPQ--FLSNEAQSLLR 294 Query: 1467 KLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFE 1625 L N RLG+ +GA E+K H +F + W KLY ++ F P V DT F+ Sbjct: 295 ALFKRNATNRLGSGVEGAEELKRHPFFSTIDWNKLYRRELSPPFKPSVTQPDDTYYFD 352 Score = 79.3 bits (194), Expect = 6e-14 Identities = 60/240 (25%), Positives = 103/240 (42%) Frame = +3 Query: 639 IGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYY 818 IG G++ + C K + YA+K + KS +R E ++ R + I+ L Sbjct: 422 IGVGSYSVCKRCVHKGTNMEYAVKVIDKS---KRDPSEEIEILRRYGQHPN---IITLKD 475 Query: 819 SFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIK 998 +++ +YL+ E + GG+++ ++R+ +E EA + +E +H +HRD+K Sbjct: 476 VYEECNSIYLVTELMRGGELLDRILRQKFFSEREACSVLFTVCKTVEYLHSQGVVHRDLK 535 Query: 999 PDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKR 1178 P N +D S P + R+ + K+ Sbjct: 536 PSNILY----------------VDESGDP------------------ESIRICDFGFSKQ 561 Query: 1179 TQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPF 1358 + E L + T +++APEVL ++GY CD WSLG ++Y ML GY PF Sbjct: 562 LRAE---------NGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPF 612
>Q8INB9:AKT1_DROME RAC serine/threonine-protein kinase - Drosophila melanogaster (Fruit| fly) Length = 611 Score = 179 bits (453), Expect = 5e-44 Identities = 114/356 (32%), Positives = 174/356 (48%), Gaps = 5/356 (1%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 K+ +E+FE L ++G+G FG+V LCREK + +YA+K LKK ++++ +V H E +L Sbjct: 260 KVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLK 319 Query: 783 EVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 + +++ L YSFQ ++ L +M+Y+ GG++ L + TED +FY AE + A+ Sbjct: 320 STNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGY 379 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H I+RD+K +N FGLCK D T G+ K Sbjct: 380 LHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK------------EDITYGRTTK----- 422 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 + GTP+Y+APEVL YG DWW G Sbjct: 423 ------------------------------TFCGTPEYLAPEVLDDNDYGQAVDWWGTGV 452 Query: 1323 IMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL- 1496 +MYEM+ G PFY+ D I+ +KFP ++ E K+L++ LL + ++RL Sbjct: 453 VMYEMICGRLPFYNRDHDVLFTLIL--VEEVKFPR--NITDEAKNLLAGLLAKDPKKRLG 508 Query: 1497 -GTKGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKFEETGAQVQ 1655 G EI+AH +F + W L K F P+V + DT+ F+K E TG V+ Sbjct: 509 GGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDK-EFTGESVE 563
>P10665:KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha - Xenopus laevis (African clawed| frog) Length = 733 Score = 178 bits (452), Expect = 7e-44 Identities = 119/358 (33%), Positives = 182/358 (50%), Gaps = 8/358 (2%) Frame = +3 Query: 576 TEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT---SRSVYAMKKLKKSEMLRRGQ 746 T +++ K DF LL ++G+G+FG+V L R+ T + +YAMK LKK+ + R + Sbjct: 47 THHVKEGSEKADQSDFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDR 106 Query: 747 VEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAK 926 V K ER++LA+V ++V+L+Y+FQ + LYLI+++L GGD+ T L ++ TE++ K Sbjct: 107 VR-TKMERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVK 165 Query: 927 FYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDY 1106 FY+AE L ++ +H I+RD+KP+N FGL K Sbjct: 166 FYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK--------------- 210 Query: 1107 TPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKG 1286 E + H +K AYS GT +Y+APEV+ ++G Sbjct: 211 ---------------------------EAIDHEKK-----AYSFCGTVEYMAPEVVNRQG 238 Query: 1287 YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLIS 1466 + DWWS G +M+EML G PF +D T I+ ++ L P+ LS+E + L+ Sbjct: 239 HSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL--KAKLGMPQ--FLSNEAQSLLR 294 Query: 1467 KLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFE 1625 L N RLG+ +GA EIK +F + W KL+ +M F P V DT F+ Sbjct: 295 ALFKRNPTNRLGSAMEGAEEIKRQPFFSTIDWNKLFRREMSPPFKPAVTQADDTYYFD 352 Score = 87.8 bits (216), Expect = 2e-16 Identities = 74/304 (24%), Positives = 132/304 (43%), Gaps = 5/304 (1%) Frame = +3 Query: 639 IGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYY 818 IG G++ + C K + YA+K + K+ +R E ++ R + I+ L Sbjct: 422 IGVGSYSVCKRCVHKGTNMEYAVKVIDKT---KRDPSEEIEILRRYGQHPN---IIALKD 475 Query: 819 SFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIK 998 +++ +Y++ E + GG+++ ++R+ +E EA + +E++H +HRD+K Sbjct: 476 VYKEGNSIYVVTELMRGGELLDRILRQKFFSEREASSVLFTVCKTVENLHSQGVVHRDLK 535 Query: 999 PDNXXXXXXXXXXXXXFGLCKPLDSSNFP-NLNEPDYTPGKGAKPLPDNTSRLTNPSAPK 1175 P N +D S P ++ D+ AK L + L P Sbjct: 536 PSNILY----------------VDESGDPESIRICDFG---FAKQLRADNGLLMTPCY-- 574 Query: 1176 RTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPP 1355 T +++APEVL ++GY CD WSLG ++Y ML GY P Sbjct: 575 -----------------------TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTP 611 Query: 1356 F---YSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGAHEIK 1523 F + P +I + + L+ +S+ KDL+S++L + +RL K ++ Sbjct: 612 FANGLGDTPEEILARIGSGKFTLRGGNWNTVSAAAKDLVSRMLHVDPHKRLTAK---QVL 668 Query: 1524 AHTW 1535 H W Sbjct: 669 QHEW 672
>Q15349:KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 - Homo sapiens (Human)| Length = 733 Score = 178 bits (452), Expect = 7e-44 Identities = 129/416 (31%), Positives = 206/416 (49%), Gaps = 11/416 (2%) Frame = +3 Query: 537 EQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCRE---KTSRSVYAM 707 E+ ++K ++ + +++ K FELL ++G+G++G+V L R+ + +YAM Sbjct: 33 EEEGVVKEIDI--SHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAM 90 Query: 708 KKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTL 887 K LKK+ + R +V K ER++LAEV+ +IVKL+Y+FQ + LYLI+++L GGD+ T Sbjct: 91 KVLKKATLKVRDRVRS-KMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTR 149 Query: 888 LMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPL 1067 L ++ TE++ KFY+AE LA++ +H I+RD+KP+N FGL K Sbjct: 150 LSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSK-- 207 Query: 1068 DSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGT 1247 E + H ++ AYS GT Sbjct: 208 ----------------------------------------EAIDHDKR-----AYSFCGT 222 Query: 1248 PDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPE 1427 +Y+APEV+ ++G+ DWWS G +M+EML G PF +D T I+ ++ L P+ Sbjct: 223 IEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALIL--KAKLGMPQ 280 Query: 1428 EAKLSSETKDLISKLL----CNVEQRLGTKGAHEIKAHTWFRGVQWEKLY--QMKAAFVP 1589 LS E + L+ L CN G G EIK H +F + W LY ++K F P Sbjct: 281 --FLSGEAQSLLRALFKRNPCN-RLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKP 337 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDAN--FVGYTYKNFEIVND 1751 V DT +F+ E A+ + S P PS +A+ F G+++ ++ + Sbjct: 338 AVGRPEDTFHFD--PEFTARTPTDSPGVP-----PSANAHHLFRGFSFVASSLIQE 386 Score = 96.7 bits (239), Expect = 3e-19 Identities = 85/341 (24%), Positives = 144/341 (42%), Gaps = 5/341 (1%) Frame = +3 Query: 615 EDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS 794 + +E+ IG G++ + C K + + YA+K + KS +R E ++ LL Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS---KRDPSEEIEI---LLRYGQH 466 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 I+ L + D +F+YL+ME + GG+++ ++R+ +E EA + ++ +H Sbjct: 467 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 526 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFP-NLNEPDYTPGKGAKPLPDNTSR 1151 +HRD+KP N D S P ++ D+ AK L Sbjct: 527 GVVHRDLKPSNILYR----------------DESGSPESIRVCDF---GFAKQLRAGNGL 567 Query: 1152 LTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 1331 L P T +++APEVL ++GY CD WSLG ++Y Sbjct: 568 LMTPCY-------------------------TANFVAPEVLKRQGYDAACDIWSLGILLY 602 Query: 1332 EMLVGYPPFYS---EDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLG 1499 ML G+ PF + + P +I + + L +S KD++SK+L + QRL Sbjct: 603 TMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRL- 661 Query: 1500 TKGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNF 1622 A ++ H W ++ Q+ V V G + F Sbjct: 662 --TAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAMAATYF 700
>P31749:AKT1_HUMAN RAC-alpha serine/threonine-protein kinase - Homo sapiens (Human)| Length = 480 Score = 178 bits (451), Expect = 9e-44 Identities = 117/358 (32%), Positives = 177/358 (49%), Gaps = 6/358 (1%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 +H++ + +FE L ++G+G FG+V L +EK + YAMK LKK ++ + +V H E + Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ L YSFQ + L +MEY GG++ L R+ +ED A+FY AE V A+ Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 261 Query: 957 ESIH-KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 + +H + N ++RD+K +N FGLCK + + Sbjct: 262 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCK---------------------EGI 300 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 D + T GTP+Y+APEVL YG DWW Sbjct: 301 KDGATMKT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWG 334 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG +MYEM+ G PFY++D I+ ++FP L E K L+S LL + +Q Sbjct: 335 LGVVMYEMMCGRLPFYNQDHEKLFELIL--MEEIRFPR--TLGPEAKSLLSGLLKKDPKQ 390 Query: 1491 RL--GTKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQV 1652 RL G++ A EI H +F G+ W+ +Y+ K + F P+V E DT+ F+ EE AQ+ Sbjct: 391 RLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFD--EEFTAQM 446
>Q7ZX15:AKT2A_XENLA RAC-beta serine/threonine-protein kinase-A - Xenopus laevis (African| clawed frog) Length = 486 Score = 177 bits (450), Expect = 1e-43 Identities = 112/346 (32%), Positives = 167/346 (48%), Gaps = 5/346 (1%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 K+ + DF+ L ++G+G FG+V L REK + YAMK L+K ++ + +V H E +L Sbjct: 151 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTLTESRVLQ 210 Query: 783 EVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 ++ L Y+FQ + L +MEY GG++ L R+ TED A+FY AE V A+E Sbjct: 211 NTKHPFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEY 270 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H N ++RDIK +N FGLCK + + D Sbjct: 271 LHSRNVVYRDIKLENLMLDKDGHVKITDFGLCK---------------------EGITDG 309 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 + T GTP+Y+APEVL YG DWW LG Sbjct: 310 ATMRT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWGLGV 343 Query: 1323 IMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRL- 1496 +MYEM+ G PFY++D I+ ++FP LS E K L++ LL + +QRL Sbjct: 344 VMYEMMCGRLPFYNQDHERLFELIL--MEEIRFPR--TLSPEAKSLLAGLLKKDPKQRLG 399 Query: 1497 -GTKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFE 1625 G A E+ +H +F + W+ + + K F P+V E+DT+ F+ Sbjct: 400 GGPNDAQEVMSHRFFVSINWQDVTERKLTPPFKPQVTSEIDTRYFD 445
>Q06226:SGK1_RAT Serine/threonine-protein kinase Sgk1 - Rattus norvegicus (Rat)| Length = 430 Score = 177 bits (449), Expect = 2e-43 Identities = 121/379 (31%), Positives = 185/379 (48%), Gaps = 9/379 (2%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDS 794 DF L +IG+G+FG+V L R K + YA+K L+K +L++ + +H+ +ERN LL V Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V L++SFQ + LY +++Y+ GG++ L R+ E A+FY AE A+ +H Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 N ++RD+KP+N FGLCK Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCK------------------------------- 245 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 E + H + GTP+Y+APEVL K+ Y DWW LGA++YE Sbjct: 246 -----------ENIEH-----NGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYE 289 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGA 1511 ML G PPFYS + I+N LK +++ + L+ LL + +RLG K Sbjct: 290 MLYGLPPFYSRNTAEMYDNILNKPLQLK-----NITNSARHLLEGLLQKDRTKRLGAKDD 344 Query: 1512 H-EIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWR 1682 EIK+H +F + W+ L K F P V+G D ++F+ E T V SS P Sbjct: 345 FMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDP-EFTEEPVPSSIGRSPDS 403 Query: 1683 KMLPS--KDA--NFVGYTY 1727 ++ + K+A F+G++Y Sbjct: 404 ILVTASVKEAAEAFLGFSY 422
>Q9UBS0:KS6B2_HUMAN Ribosomal protein S6 kinase beta-2 - Homo sapiens (Human)| Length = 482 Score = 177 bits (449), Expect = 2e-43 Identities = 122/384 (31%), Positives = 190/384 (49%), Gaps = 9/384 (2%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKLKKSEMLRRGQ-VEHVKAER 770 ++G FELL ++G+G +G+V R+ + +YAMK L+K++++R + H +AER Sbjct: 61 RIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAER 120 Query: 771 NLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVL 950 N+L V +IV+L Y+FQ LYLI+E L GG++ T L R+ ED A FY+AE L Sbjct: 121 NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL 180 Query: 951 AIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKP 1130 A+ +H I+RD+KP+N FGLCK +++E GA Sbjct: 181 ALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCK-------ESIHE-------GA-- 224 Query: 1131 LPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWW 1310 + ++ GT +Y+APE+L++ G+ DWW Sbjct: 225 -------------------------------VTHTFCGTIEYMAPEILVRSGHNRAVDWW 253 Query: 1311 SLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVE 1487 SLGA+MY+ML G PPF +E+ T KI+ R L P L+ + +DL+ K L N Sbjct: 254 SLGALMYDMLTGSPPFTAENRKKTMDKII--RGKLALP--PYLTPDARDLVKKFLKRNPS 309 Query: 1488 QRL--GTKGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGAQVQ 1655 QR+ G A +++ H +FR + W+ L +++ F P + E D F+ V Sbjct: 310 QRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVD 369 Query: 1656 SSSKAGPWRKMLPSKDANFVGYTY 1727 S + S + F+G+TY Sbjct: 370 SPDDTA----LSESANQAFLGFTY 389
>Q6PFQ0:KS6A6_DANRE Ribosomal protein S6 kinase alpha-6 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 740 Score = 177 bits (449), Expect = 2e-43 Identities = 129/394 (32%), Positives = 195/394 (49%), Gaps = 10/394 (2%) Frame = +3 Query: 576 TEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCRE---KTSRSVYAMKKLKKSEMLRRGQ 746 T +++ K FELL ++G+G+FG+V L R+ + +YAMK LKK+ + R + Sbjct: 52 THHVKEGCEKADPSQFELLKVLGQGSFGKVFLVRKLMGPDAGQLYAMKVLKKASLKVRDR 111 Query: 747 VEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAK 926 V K ER++L EV+ +IVKL+Y+FQ + LYLI+++L GGD+ T L ++ TE++ K Sbjct: 112 VR-TKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVMFTEEDVK 170 Query: 927 FYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDY 1106 FY+AE LA++ +H ++RD+KP+N FGL K Sbjct: 171 FYLAELALALDHLHNLGIVYRDLKPENILLDEAGHIKLTDFGLSK--------------- 215 Query: 1107 TPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKG 1286 E + +K AYS GT +Y+APEV+ ++G Sbjct: 216 ---------------------------ESVDQDKK-----AYSFCGTVEYMAPEVVNRRG 243 Query: 1287 YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLIS 1466 + DWWSLG +M+EML G PF +D T I+ ++ L P+ LS E + L+ Sbjct: 244 HTQSADWWSLGVLMFEMLTGTLPFQGKDRNETMNMIL--KAKLGMPQ--FLSLEAQGLLR 299 Query: 1467 KLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKF 1631 L N RLG G EIK HT+F + W KLY +++ F P DT F+ Sbjct: 300 MLFKRNPSNRLGAGPDGVEEIKRHTFFSTIDWNKLYRRELQPPFKPASGKPDDTFCFD-- 357 Query: 1632 EETGAQVQSSSKAGPWRKMLPSKDAN--FVGYTY 1727 E A+ S P PS +A+ F G+++ Sbjct: 358 PEFTAKTPKDSPGIP-----PSANAHQLFKGFSF 386 Score = 92.4 bits (228), Expect = 7e-18 Identities = 75/308 (24%), Positives = 131/308 (42%), Gaps = 3/308 (0%) Frame = +3 Query: 621 FELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAY 800 +EL IG G++ + C + + +A+K + KS +R E ++ L+ Sbjct: 420 YELKEDIGVGSYSICKRCIHRVTAMEFAVKIIDKS---KRDPSEEIEI---LMRYGQHPN 473 Query: 801 IVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNY 980 I+ L + + F+YL+ E + GG+++ ++R+ +E EA + ++ +H Sbjct: 474 IITLKDVYDEGRFVYLVTELMKGGELLDKILRQKFFSEREASAVLYTITKTVDYLHCQGV 533 Query: 981 IHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTN 1160 +HRD+KP N DS N ++ D+ AK L + L Sbjct: 534 VHRDLKPSNILYMD---------------DSGNPDSIRICDFG---FAKQLRGDNGLLLT 575 Query: 1161 PSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEML 1340 P T +++APEVL+++GY CD WSLG ++Y ML Sbjct: 576 PCY-------------------------TANFVAPEVLMRQGYDAACDIWSLGVLLYTML 610 Query: 1341 VGYPPFY---SEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGA 1511 GY PF ++ P +I + + L +S +KDL+S +L T A Sbjct: 611 AGYTPFANGPNDTPEEILLRIGSGKFSLSGGNWDSVSDSSKDLLSHMLHVDPHHRYT--A 668 Query: 1512 HEIKAHTW 1535 ++ H+W Sbjct: 669 EQVLKHSW 676
>Q6IP76:AKT2B_XENLA RAC-beta serine/threonine-protein kinase-B - Xenopus laevis (African| clawed frog) Length = 485 Score = 177 bits (449), Expect = 2e-43 Identities = 113/348 (32%), Positives = 168/348 (48%), Gaps = 5/348 (1%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 R K+ + DF+ L ++G+G FG+V L REK + YAMK L+K ++ + +V H E + Sbjct: 148 RPKVTMNDFDYLKLLGKGTFGKVILVREKATGLYYAMKILRKEVIIAKDEVAHTLTESRV 207 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ L Y+FQ + L +MEY GG++ L R+ TED A+FY AE V A+ Sbjct: 208 LQNTKHPFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSAL 267 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLP 1136 E +H N ++RDIK +N FGLCK + + Sbjct: 268 EYLHSRNVVYRDIKLENLMLDKDGHVKITDFGLCK---------------------EGIT 306 Query: 1137 DNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSL 1316 D + T GTP+Y+APEVL YG DWW L Sbjct: 307 DGATMRT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWGL 340 Query: 1317 GAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQR 1493 G +MYEM+ G PFY++D I+ +FP LS E K L++ LL + +QR Sbjct: 341 GVVMYEMMCGRLPFYNQDHERLFELIL--MEETRFPR--TLSPEAKSLLAGLLKKDPKQR 396 Query: 1494 L--GTKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFE 1625 L G A E+ +H +F + W+ + + K + F P+V E+DT+ F+ Sbjct: 397 LGGGPDDAQEVMSHGFFASINWQDVTERKLSPPFKPQVTSEIDTRYFD 444
>Q9Z1M4:KS6B2_MOUSE Ribosomal protein S6 kinase beta-2 - Mus musculus (Mouse)| Length = 485 Score = 177 bits (448), Expect = 2e-43 Identities = 140/466 (30%), Positives = 220/466 (47%), Gaps = 21/466 (4%) Frame = +3 Query: 585 MRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKLKKSEMLRRGQ-VE 752 + L ++G FELL+++G+G +G+V R+ + +YAMK L+K++++ + Sbjct: 55 VNLGPERIGPHCFELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTA 114 Query: 753 HVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFY 932 H +AERN+L V +IV+L Y+FQ LYLI+E L GG++ T L R+ ED A FY Sbjct: 115 HTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFY 174 Query: 933 IAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTP 1112 +AE LA+ +H H I+RD+KP+N FGLCK +++E Sbjct: 175 LAEITLALGHLHSHGIIYRDLKPENIMLSSQGHIKLTDFGLCK-------ESIHE----- 222 Query: 1113 GKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYG 1292 GA + ++ GT +Y+APE+L++ G+ Sbjct: 223 --GA---------------------------------ITHTFCGTIEYMAPEILVRTGHN 247 Query: 1293 MECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKL 1472 DWWSLGA+MY+ML G PPF +E+ T KI+ + L P L+ + +DL K Sbjct: 248 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKII--KGKLVLP--PYLTPDARDLAKKF 303 Query: 1473 L-CNVEQRL--GTKGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKFEE 1637 L N QR+ G A +++ H +FR + W+ L ++ F P + E D F+ Sbjct: 304 LKRNPTQRIGGGLGDAADVQRHPFFRHINWDDLLARRVDPPFRPSLQSEEDVSQFDARFT 363 Query: 1638 TGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAELKKKS----SKSKR 1805 V S + S + F+G+TY +++ + + K +S + S R Sbjct: 364 RQTPVDSPDDTA----LSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPR 419 Query: 1806 PTIKTL----FE----SMDEDEPVHGSFLNMLPHKEGQPSSHSSAP 1919 I L FE S EP+ S +LP P + S+AP Sbjct: 420 TPISPLKFSPFEGFRPSPGPPEPMEPSLPPLLPSPPSPPPT-STAP 464
>Q8C050:KS6A5_MOUSE Ribosomal protein S6 kinase alpha-5 - Mus musculus (Mouse)| Length = 863 Score = 177 bits (448), Expect = 2e-43 Identities = 134/447 (29%), Positives = 215/447 (48%), Gaps = 17/447 (3%) Frame = +3 Query: 567 KKETEYMRLQRH--KMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKLKKSEM 731 K E L H K+G+E+FELL ++G GA+G+V L R+ + +YAMK LKK+ + Sbjct: 28 KHELRTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDAGKLYAMKVLKKATI 87 Query: 732 LRRGQV-EHVKAERNLLAEV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDT 905 +++ + EH + ER +L + S ++V L+Y+FQ + L+LI++Y+ GG++ T L +++ Sbjct: 88 VQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRER 147 Query: 906 LTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFP 1085 TE E + Y+ E VLA+E +HK I+RDIK +N FGL K Sbjct: 148 FTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEF------ 201 Query: 1086 NLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAP 1265 + D T R AYS GT +Y+AP Sbjct: 202 ---------------VADETER-------------------------AYSFCGTIEYMAP 221 Query: 1266 EVLL--KKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVN--WRSHLKFPEEA 1433 +++ G+ DWWSLG +MYE+L G PF + ++ +I +S +P+E Sbjct: 222 DIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQE- 280 Query: 1434 KLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVN 1598 +S+ KDL+ +LL + ++RL G + A EIK H +F ++W+ L K A F P + Sbjct: 281 -MSTVAKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKIKWDDLAAKKVPAPFKPVIR 339 Query: 1599 GELDTQNF-EKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAE 1775 ELD NF E+F E ++ + S + F GY++ I+ A I Sbjct: 340 DELDVSNFAEEFTEMDPTYSPAA-------LPQSSERLFQGYSFVAPSILFKRNAAVIDP 392 Query: 1776 LKKKSSKSKRPTIKTLFESMDEDEPVH 1856 L+ + +M +D P + Sbjct: 393 LQFHMGVDRPGVTNVARSAMMKDSPFY 419 Score = 83.6 bits (205), Expect = 3e-15 Identities = 66/218 (30%), Positives = 86/218 (39%), Gaps = 7/218 (3%) Frame = +3 Query: 843 YLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXX 1022 +L+ME L GG++ + RK +E EA + + + V A+ +H +HRD+KP+N Sbjct: 559 FLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTD 618 Query: 1023 XXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSH 1202 K +D F L PD P K Sbjct: 619 ENDNLEI-----KVIDFG-FARLKPPDNQPLK---------------------------- 644 Query: 1203 WQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMST 1382 + T Y APE+L GY CD WSLG I+Y ML G PF S D T Sbjct: 645 ----------TPCFTLHYAAPELLTHNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLT 694 Query: 1383 CRKIVNWRSHLK-----FPEEA--KLSSETKDLISKLL 1475 C V +K F EA +S E KDLI LL Sbjct: 695 CTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLL 732
>O75582:KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 - Homo sapiens (Human)| Length = 802 Score = 177 bits (448), Expect = 2e-43 Identities = 135/447 (30%), Positives = 215/447 (48%), Gaps = 17/447 (3%) Frame = +3 Query: 567 KKETEYMRLQRH--KMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKLKKSEM 731 K E L H K+G+E+FELL ++G GA+G+V L R+ + +YAMK LKK+ + Sbjct: 29 KHELRTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATI 88 Query: 732 LRRGQV-EHVKAERNLLAEV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDT 905 +++ + EH + ER +L + S ++V L+Y+FQ + L+LI++Y+ GG++ T L +++ Sbjct: 89 VQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRER 148 Query: 906 LTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFP 1085 TE E + Y+ E VLA+E +HK I+RDIK +N FGL K Sbjct: 149 FTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEF------ 202 Query: 1086 NLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAP 1265 + D T R AYS GT +Y+AP Sbjct: 203 ---------------VADETER-------------------------AYSFCGTIEYMAP 222 Query: 1266 EVLL--KKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVN--WRSHLKFPEEA 1433 +++ G+ DWWSLG +MYE+L G PF + ++ +I +S +P+E Sbjct: 223 DIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQE- 281 Query: 1434 KLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVN 1598 +S+ KDLI +LL + ++RL G + A EIK H +F+ + W+ L K A F P + Sbjct: 282 -MSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIR 340 Query: 1599 GELDTQNF-EKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAE 1775 ELD NF E+F E ++ + S + F GY++ I+ A I Sbjct: 341 DELDVSNFAEEFTEMDPTYSPAA-------LPQSSEKLFQGYSFVAPSILFKRNAAVIDP 393 Query: 1776 LKKKSSKSKRPTIKTLFESMDEDEPVH 1856 L+ + +M +D P + Sbjct: 394 LQFHMGVERPGVTNVARSAMMKDSPFY 420 Score = 99.4 bits (246), Expect = 5e-20 Identities = 83/286 (29%), Positives = 112/286 (39%), Gaps = 7/286 (2%) Frame = +3 Query: 639 IGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYY 818 +G G+F R C K S +A+K + K R + K L IVKL+ Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISK-----RMEANTQKEITALKLCEGHPNIVKLHE 486 Query: 819 SFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIK 998 F D +L+ME L GG++ + +K +E EA + + + V A+ +H +HRD+K Sbjct: 487 VFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLK 546 Query: 999 PDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKR 1178 P+N L + F L PD P K Sbjct: 547 PENLLFTDEND------NLEIKIIDFGFARLKPPDNQPLK-------------------- 580 Query: 1179 TQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPF 1358 + T Y APE+L + GY CD WSLG I+Y ML G PF Sbjct: 581 ------------------TPCFTLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPF 622 Query: 1359 YSEDPMSTCRKIVNWRSHLK-----FPEEA--KLSSETKDLISKLL 1475 S D TC V +K F EA +S E KDLI LL Sbjct: 623 QSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLL 668
>Q9Z2B9:KS6A4_MOUSE Ribosomal protein S6 kinase alpha-4 - Mus musculus (Mouse)| Length = 773 Score = 177 bits (448), Expect = 2e-43 Identities = 140/478 (29%), Positives = 229/478 (47%), Gaps = 13/478 (2%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKLKKSEMLRRGQV-EHVKAER 770 K+ VE+F LL ++G GA+G+V L R+ +YAMK L+K+ +++R + EH + ER Sbjct: 27 KVSVENFALLKVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTER 86 Query: 771 NLLAEVDSA-YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETV 947 ++L V A ++V L+Y+FQ D L+LI++Y+ GG+M T L ++ E E + Y E V Sbjct: 87 SVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIV 146 Query: 948 LAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAK 1127 LA+E +HK I+RD+K +N FGL K L E Sbjct: 147 LALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEF-------LTE---------- 189 Query: 1128 PLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKK-GYGMECD 1304 +K R +S GT +Y+APE++ K G+G D Sbjct: 190 --------------------------EKER---TFSFCGTIEYMAPEIIRSKAGHGKAVD 220 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WWSLG +++E+L G PF E +T ++ P ++ +DL+ +LLC + Sbjct: 221 WWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPLRIGPVAQDLLQRLLCKD 280 Query: 1482 VEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKFEETGAQ 1649 ++RLG +GA E+K+H +F+G+ W L K A F P++ ELD NF + Sbjct: 281 PKKRLGAGPQGAQEVKSHPFFQGLDWWALAARKIPAPFRPQIRSELDVGNFAEEFTRLEP 340 Query: 1650 VQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAELKKKSSKSKRPTIKTLFE 1829 V S + + P P F GY++ I+ D A +A++ + RP + Sbjct: 341 VYSPAGSPP-----PGDPRIFQGYSFVAPSILFDHNNAVMADVLQAPGAGYRPGRAAVAR 395 Query: 1830 S-MDEDEPVHGSF-LNMLPHKEGQPSSHSSAPPEQYQPRRK*DMEVLKSKPQKSKREE 1997 S M +D P + L++ GQ S Q Q ++ +++L + +++ + E Sbjct: 396 SAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEENTQRE 453 Score = 89.0 bits (219), Expect = 7e-17 Identities = 84/311 (27%), Positives = 130/311 (41%), Gaps = 10/311 (3%) Frame = +3 Query: 639 IGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYY 818 +G+G+F R CR++ S +A+K L S L V A R + + +V L+ Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKIL--SRRLEENTQREVAALRLCQSHPN---VVNLHE 471 Query: 819 SFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH-NYIHRDI 995 D YL++E L GG+++ + +K +E EA + V A+ +H+ +HRD+ Sbjct: 472 VLHDQLHTYLVLELLRGGELLEHIRKKRLFSESEASQILRSLVSAVSFMHEEAGVVHRDL 531 Query: 996 KPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPK 1175 KP+N D TPG K + +RL P +P Sbjct: 532 KPENILYA---------------------------DDTPGAPVKIIDFGFARL-RPQSPA 563 Query: 1176 RTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPP 1355 Q + T Y APE+L ++GY CD WSLG I+Y ML G P Sbjct: 564 EPMQ---------------TPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVP 608 Query: 1356 F--------YSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKG 1508 F S+ C KI R L +S E K+L+ LL + +RL +G Sbjct: 609 FQGASGQGGQSQAAEIMC-KIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEG 667 Query: 1509 AHEIKAHTWFR 1541 +++ +W + Sbjct: 668 ---LRSSSWLQ 675
>Q98TY9:AKT1_XENLA RAC-alpha serine/threonine-protein kinase - Xenopus laevis (African| clawed frog) Length = 481 Score = 176 bits (447), Expect = 3e-43 Identities = 122/378 (32%), Positives = 181/378 (47%), Gaps = 6/378 (1%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 +HK+ + +FE L ++G+G FG+V L +EK + YAMK LKK ++ + +V H E + Sbjct: 143 KHKVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 202 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ L YSFQ + L +MEY GG++ L R+ +ED A+FY AE V A+ Sbjct: 203 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERIFSEDRARFYGAEIVSAL 262 Query: 957 ESIH-KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 + +H + N ++RD+K +N FGLCK + + Sbjct: 263 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCK---------------------EGI 301 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 D + T GTP+Y+APEVL YG DWW Sbjct: 302 KDGATMKT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWG 335 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG +MYEM+ G PFY++D I+ ++FP L E K L+S LL + +Q Sbjct: 336 LGVVMYEMMCGRLPFYNQDHEKLFELIL--MEEIRFPR--TLLPEAKSLLSGLLKKDPKQ 391 Query: 1491 RL--GTKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQVQS 1658 RL G A EI H +F G+ W+ +Y+ K F P+V E DT+ F+ EE AQ+ + Sbjct: 392 RLGGGPDDAKEIMQHKFFAGIVWQDVYEKKLVPPFKPQVTSETDTRYFD--EEFTAQMIT 449 Query: 1659 SSKAGPWRKMLPSKDANF 1712 + P +D NF Sbjct: 450 ITP--------PDQDDNF 459
>Q01314:AKT1_BOVIN RAC-alpha serine/threonine-protein kinase - Bos taurus (Bovine)| Length = 480 Score = 176 bits (447), Expect = 3e-43 Identities = 117/358 (32%), Positives = 176/358 (49%), Gaps = 6/358 (1%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 +H++ + DFE L ++G+G FG+V L +EK + YAMK LKK ++ + +V H E + Sbjct: 142 KHRVTMNDFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ L YSFQ + L +MEY GG++ L R+ +ED A+FY AE V A+ Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 261 Query: 957 ESIH-KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 + +H + ++RD+K +N FGLCK + + Sbjct: 262 DYLHSEKEVVYRDLKLENLMLDKDGHIKITDFGLCK---------------------EGI 300 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 D + T GTP+Y+APEVL YG DWW Sbjct: 301 KDGATMKT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWG 334 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG +MYEM+ G PFY++D I+ ++FP LS E K L+S LL + +Q Sbjct: 335 LGVVMYEMMCGRLPFYNQDHEKLFELIL--MEEIRFPR--TLSPEAKSLLSGLLKKDPKQ 390 Query: 1491 RL--GTKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQV 1652 RL G++ A EI H +F + W+ +Y+ K + F P+V E DT+ F+ EE AQ+ Sbjct: 391 RLGGGSEDAKEIMQHRFFASIVWQDVYEKKLSPPFKPQVTSETDTRYFD--EEFTAQM 446
>Q8R4U9:SGK2_RAT Serine/threonine-protein kinase Sgk2 - Rattus norvegicus (Rat)| Length = 367 Score = 176 bits (446), Expect = 3e-43 Identities = 126/388 (32%), Positives = 188/388 (48%), Gaps = 7/388 (1%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDS 794 DF+ L +IG+G +G+V L + K+ + YA+K L+K +L+ + H+ AERN LL V Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAERNVLLKNVRH 93 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V L YSFQ E LY +++Y+ GG++ L R+ E A+FY AE AI +H Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAEVASAIGYLHSL 153 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 N I+RD+KP+N FGLCK EP+ T Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCK--------ECVEPEETTS------------- 192 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 + GTP+Y+APEVL K+ Y DWW LGA++YE Sbjct: 193 --------------------------TFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYE 226 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGA 1511 ML G PPF++ D I++ L+ P +++ DL+ LL + QRLG+K Sbjct: 227 MLHGLPPFFNTDVAQMYENILH--QPLQIPGGRTVAA--CDLLQGLLHKDQRQRLGSKED 282 Query: 1512 H-EIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWR 1682 +IK H +F + W+ LY ++ F P V G D ++F+ E T V S P Sbjct: 283 FLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDP-EFTQEAVSKSIGCTP-D 340 Query: 1683 KMLPSKDAN--FVGYTYKNFEIVNDDEV 1760 M S A+ F+G++Y +DD++ Sbjct: 341 TMSSSSGASSAFLGFSYAQ----DDDDI 364
>Q9WVC6:SGK1_MOUSE Serine/threonine-protein kinase Sgk1 - Mus musculus (Mouse)| Length = 431 Score = 176 bits (446), Expect = 3e-43 Identities = 121/379 (31%), Positives = 184/379 (48%), Gaps = 9/379 (2%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDS 794 DF L +IG+G+FG+V L R K YA+K L+K +L++ + +H+ +ERN LL V Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V L++SFQ + LY +++Y+ GG++ L R+ E A+FY AE A+ +H Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 N ++RD+KP+N FGLCK Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCK------------------------------- 245 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 E + H + GTP+Y+APEVL K+ Y DWW LGA++YE Sbjct: 246 -----------ENIEH-----NGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYE 289 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGA 1511 ML G PPFYS + I+N LK +++ + L+ LL + +RLG K Sbjct: 290 MLYGLPPFYSRNTAEMYDNILNKPLQLK----PNITNSARHLLEGLLQKDRTKRLGAKDD 345 Query: 1512 H-EIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWR 1682 EIK+H +F + W+ L K F P V+G D ++F+ E T V SS P Sbjct: 346 FMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDP-EFTEEPVPSSIGRSPDS 404 Query: 1683 KMLPS--KDA--NFVGYTY 1727 ++ + K+A F+G++Y Sbjct: 405 ILVTASVKEAAEAFLGFSY 423
>O00141:SGK1_HUMAN Serine/threonine-protein kinase Sgk1 - Homo sapiens (Human)| Length = 431 Score = 176 bits (446), Expect = 3e-43 Identities = 120/379 (31%), Positives = 184/379 (48%), Gaps = 9/379 (2%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDS 794 DF L +IG+G+FG+V L R K YA+K L+K +L++ + +H+ +ERN LL V Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V L++SFQ + LY +++Y+ GG++ L R+ E A+FY AE A+ +H Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 N ++RD+KP+N FGLCK Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCK------------------------------- 245 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 E + H + GTP+Y+APEVL K+ Y DWW LGA++YE Sbjct: 246 -----------ENIEH-----NSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYE 289 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGA 1511 ML G PPFYS + I+N LK +++ + L+ LL + +RLG K Sbjct: 290 MLYGLPPFYSRNTAEMYDNILNKPLQLK----PNITNSARHLLEGLLQKDRTKRLGAKDD 345 Query: 1512 H-EIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWR 1682 EIK+H +F + W+ L K F P V+G D ++F+ E T V +S P Sbjct: 346 FMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDP-EFTEEPVPNSIGKSPDS 404 Query: 1683 KMLPS--KDA--NFVGYTY 1727 ++ + K+A F+G++Y Sbjct: 405 VLVTASVKEAAEAFLGFSY 423
>Q8R4V0:SGK3_RAT Serine/threonine-protein kinase Sgk3 - Rattus norvegicus (Rat)| Length = 496 Score = 176 bits (445), Expect = 4e-43 Identities = 141/492 (28%), Positives = 213/492 (43%), Gaps = 15/492 (3%) Frame = +3 Query: 297 FQKFQPRDK---SKSPAVPASHGKDPGKPPV-DDAPSSATKQKVAAAKQYIENHYKTQMK 464 F+++ DK S PA K P K D+ KQ+ A ++I+N + Sbjct: 48 FRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQN--LVRYP 105 Query: 465 SLQDRKERRWMLE----RKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELL 632 L + + R L+ R D +E++ H + DF+ L Sbjct: 106 ELYNHPDVRAFLQMDSPRHQSDPSEDEDERSTPKPHSTSRNINLGPTGNPHAKPSDFDFL 165 Query: 633 TIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDSAYIVK 809 +IG+G+FG+V L + K YA+K L+K +L R + +H+ AERN LL V ++V Sbjct: 166 KVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVG 225 Query: 810 LYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHR 989 L+YSFQ E LY +++++ GG++ L R+ + E A+FY AE A+ +H ++R Sbjct: 226 LHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYR 285 Query: 990 DIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSA 1169 D+KP+N FGLCK + D T+ Sbjct: 286 DLKPENILLDSMGHVVLTDFGLCKE-------------------GIAISDTTT------- 319 Query: 1170 PKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGY 1349 + GTP+Y+APEV+ K+ Y DWW LGA++YEML G Sbjct: 320 ---------------------TFCGTPEYLAPEVIRKQPYDRTVDWWCLGAVLYEMLYGL 358 Query: 1350 PPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAH-EIKA 1526 PPFY D I++ +L+ S ++L+ K N + RLG K EI+ Sbjct: 359 PPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEK---NRQNRLGAKEDFLEIQN 415 Query: 1527 HTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKF---EETGAQVQSSSKAGPWRKML 1691 H +F + W L Q K F P V G D +NF+ E V SS + Sbjct: 416 HPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASV 475 Query: 1692 PSKDANFVGYTY 1727 D FVG++Y Sbjct: 476 LEADDAFVGFSY 487
>Q9XT18:SGK1_RABIT Serine/threonine-protein kinase Sgk1 - Oryctolagus cuniculus (Rabbit)| Length = 431 Score = 176 bits (445), Expect = 4e-43 Identities = 120/379 (31%), Positives = 184/379 (48%), Gaps = 9/379 (2%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDS 794 DF L +IG+G+FG+V L R K + YA+K L+K +L++ + +H+ +ERN LL V Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V L++SFQ + LY +++Y+ GG++ L R+ E A+FY AE A+ +H Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 N ++RD+KP+N FGLCK Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCK------------------------------- 245 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 E + H + GTP+Y+APEVL K+ Y DWW LGA++YE Sbjct: 246 -----------ENIEH-----NGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYE 289 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGA 1511 ML G PPFYS + I+N LK +++ + L+ LL + +RLG K Sbjct: 290 MLYGLPPFYSRNTAEMYDNILNKPLQLK----PNITNSARHLLEGLLQKDRTKRLGAKDD 345 Query: 1512 H-EIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWR 1682 EI+ H +F + W+ L K F P V+G D ++F+ E T V SS P Sbjct: 346 FMEIRNHVFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDP-EFTEEPVPSSIGRSPDS 404 Query: 1683 KMLPS--KDA--NFVGYTY 1727 ++ + K+A F+G++Y Sbjct: 405 ILITASVKEAAEAFLGFSY 423
>Q12706:PSK1_SCHPO Serine/threonine-protein kinase psk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 436 Score = 176 bits (445), Expect = 4e-43 Identities = 111/348 (31%), Positives = 175/348 (50%), Gaps = 8/348 (2%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQ-VEHVKAERNLL 779 KM DF+ LT++GRG++G+V L ++K + ++A K+LKK+ ++ R + +E K ER +L Sbjct: 85 KMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQIL 144 Query: 780 AEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 EV +I +LYY+FQD + LYLI++Y PGG++ + L + L ED FY AE LA+ Sbjct: 145 EEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALI 204 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPD 1139 +HK ++RD+KP+N FGL K ++ GA Sbjct: 205 HLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAEN---------------GAD---- 245 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLG 1319 S VGT +Y APE+LL++ Y DWWS+G Sbjct: 246 -----------------------------CRSFVGTEEYCAPEILLEQPYDHAVDWWSMG 276 Query: 1320 AIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRL 1496 +++++L G PPF + + KI + ++ F ++S+ +D+I+K L N +QRL Sbjct: 277 ILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPF----YVTSDARDIINKFLKKNPKQRL 332 Query: 1497 GT----KGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNF 1622 G KG IK H +R + W KL + + VP + +NF Sbjct: 333 GADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPCITNPEAAENF 380
>P40376:KAPB_SCHPO cAMP-dependent protein kinase catalytic subunit - Schizosaccharomyces| pombe (Fission yeast) Length = 512 Score = 176 bits (445), Expect = 4e-43 Identities = 117/431 (27%), Positives = 204/431 (47%), Gaps = 7/431 (1%) Frame = +3 Query: 390 PSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEK 569 P SA++ ++ Q + ++ S + ERR ++ L+D + + +L + Sbjct: 127 PESASRSSSQSSHQRHSRDGRGELGS--EHGERRSAMDG-LRDRHIRKVRVSQLLDLQRR 183 Query: 570 KETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQV 749 + + + G++DF L +G G+FG V L + +R YA+K L+K +++ Q+ Sbjct: 184 RIRPADHTTKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQI 243 Query: 750 EHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKF 929 EH ER +L+ V +I L+ +FQD + L+++M++ GG++ +LL + E AKF Sbjct: 244 EHTCDERYILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKF 303 Query: 930 YIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNL-NEPDY 1106 Y AE +LA++ +H + ++RD+KP+N FG K + +SN L PDY Sbjct: 304 YAAEVILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCCTLCGTPDY 363 Query: 1107 TPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKG 1286 +APE++ K Sbjct: 364 --------------------------------------------------LAPEIISLKP 373 Query: 1287 YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLIS 1466 Y DWWSLG +++EML GYPPFYSE+PM I+ + + +P + S + DL+S Sbjct: 374 YNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGK--VNYP--SYFSPASIDLLS 429 Query: 1467 KLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVN-GELDTQNFEK 1628 LL ++ R G G+ +I H WFR + W+K+ +++ +VP + G D+ F+ Sbjct: 430 HLLQRDITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPPIQAGMGDSSQFDA 489 Query: 1629 FEETGAQVQSS 1661 + + +S Sbjct: 490 YADVATDYGTS 500
>Q9ERE3:SGK3_MOUSE Serine/threonine-protein kinase Sgk3 - Mus musculus (Mouse)| Length = 496 Score = 175 bits (444), Expect = 6e-43 Identities = 141/492 (28%), Positives = 213/492 (43%), Gaps = 15/492 (3%) Frame = +3 Query: 297 FQKFQPRDK---SKSPAVPASHGKDPGKPPV-DDAPSSATKQKVAAAKQYIENHYKTQMK 464 F+++ DK S PA K P K D+ KQ+ A ++I+N + Sbjct: 48 FRRYAEFDKLYNSLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQN--LVRYP 105 Query: 465 SLQDRKERRWMLE----RKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELL 632 L + + R L+ R D +E++ H + DF+ L Sbjct: 106 ELYNHPDVRAFLQMDSPRHQSDPSEDEDERSTSKPHSTSRNINLGPTGNPHAKPTDFDFL 165 Query: 633 TIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDSAYIVK 809 +IG+G+FG+V L + K YA+K L+K +L R + +H+ AERN LL V ++V Sbjct: 166 KVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVG 225 Query: 810 LYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHR 989 L+YSFQ E LY +++++ GG++ L R+ + E A+FY AE A+ +H ++R Sbjct: 226 LHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYR 285 Query: 990 DIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSA 1169 D+KP+N FGLCK + D T+ Sbjct: 286 DLKPENILLDSMGHVVLTDFGLCKE-------------------GIAISDTTT------- 319 Query: 1170 PKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGY 1349 + GTP+Y+APEV+ K+ Y DWW LGA++YEML G Sbjct: 320 ---------------------TFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGL 358 Query: 1350 PPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAH-EIKA 1526 PPFY D I++ +L+ S ++L+ K N + RLG K EI+ Sbjct: 359 PPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEK---NRQNRLGAKEDFLEIQN 415 Query: 1527 HTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKF---EETGAQVQSSSKAGPWRKML 1691 H +F + W L Q K F P V G D +NF+ E V SS + Sbjct: 416 HPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASV 475 Query: 1692 PSKDANFVGYTY 1727 D FVG++Y Sbjct: 476 LEADDAFVGFSY 487
>Q16512:PKN1_HUMAN Serine/threonine-protein kinase N1 - Homo sapiens (Human)| Length = 942 Score = 175 bits (444), Expect = 6e-43 Identities = 122/387 (31%), Positives = 190/387 (49%), Gaps = 8/387 (2%) Frame = +3 Query: 591 LQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAER 770 L++ + +EDF+ L ++GRG FG+V L + S ++A+K LKK +++ R +VE + E+ Sbjct: 605 LRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEK 664 Query: 771 NLLAEVDSA---YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAE 941 +LA V SA ++V L+ FQ E + +MEY GGD+M L + D +E A FY A Sbjct: 665 RILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAIFYSAC 723 Query: 942 TVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKG 1121 VL ++ +H+H ++RD+K DN FGLCK G G Sbjct: 724 VVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCK----------------EGMG 767 Query: 1122 AKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMEC 1301 D TS + GTP+++APEVL Y Sbjct: 768 ---YGDRTS----------------------------TFCGTPEFLAPEVLTDTSYTRAV 796 Query: 1302 DWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-C 1478 DWW LG ++YEMLVG PF +D IVN +++P LS+E ++ +LL Sbjct: 797 DWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVN--DEVRYPR--FLSAEAIGIMRRLLRR 852 Query: 1479 NVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKFEETGA 1646 N E+RLG+ + A ++K +FR + WE L ++ FVP ++G D NF+ EE Sbjct: 853 NPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFD--EEFTG 910 Query: 1647 QVQSSSKAGPWRKMLPSKDANFVGYTY 1727 + + S R + ++ A F+ + + Sbjct: 911 EAPTLSPPRDARPLTAAEQAAFLDFDF 937
>P31748:AKT_MLVAT AKT kinase-transforming protein - AKT8 murine leukemia virus| Length = 501 Score = 175 bits (443), Expect = 8e-43 Identities = 116/358 (32%), Positives = 175/358 (48%), Gaps = 6/358 (1%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 +H++ + +FE L ++G+G FG+V L +EK + YAMK LKK ++ + +V H E + Sbjct: 163 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 222 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ L YSFQ + L +MEY GG++ L R+ +ED A+FY AE V A+ Sbjct: 223 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 282 Query: 957 ESIH-KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 + +H + N ++RD+K +N FGLCK + + Sbjct: 283 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCK---------------------EGI 321 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 D + T GTP+Y+APEVL YG DWW Sbjct: 322 KDGATMKT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWG 355 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG +MYEM+ G PFY++D I+ ++FP L E K L+S LL + Q Sbjct: 356 LGVVMYEMMCGRLPFYNQDHEKLFELIL--MEEIRFPR--TLGPEAKSLLSGLLKKDPTQ 411 Query: 1491 RL--GTKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQV 1652 RL G++ A EI H +F + W+ +Y+ K + F P+V E DT+ F+ EE AQ+ Sbjct: 412 RLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFD--EEFTAQM 467
>P47196:AKT1_RAT RAC-alpha serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 480 Score = 175 bits (443), Expect = 8e-43 Identities = 116/358 (32%), Positives = 175/358 (48%), Gaps = 6/358 (1%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 +H++ + +FE L ++G+G FG+V L +EK + YAMK LKK ++ + +V H E + Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ L YSFQ + L +MEY GG++ L R+ +ED A+FY AE V A+ Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 261 Query: 957 ESIH-KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 + +H + N ++RD+K +N FGLCK + + Sbjct: 262 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCK---------------------EGI 300 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 D + T GTP+Y+APEVL YG DWW Sbjct: 301 KDGATMKT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWG 334 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG +MYEM+ G PFY++D I+ ++FP L E K L+S LL + Q Sbjct: 335 LGVVMYEMMCGRLPFYNQDHEKLFELIL--MEEIRFPR--TLGPEAKSLLSGLLKKDPTQ 390 Query: 1491 RL--GTKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQV 1652 RL G++ A EI H +F + W+ +Y+ K + F P+V E DT+ F+ EE AQ+ Sbjct: 391 RLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFD--EEFTAQM 446
>Q9QZS5:SGK2_MOUSE Serine/threonine-protein kinase Sgk2 - Mus musculus (Mouse)| Length = 367 Score = 174 bits (442), Expect = 1e-42 Identities = 124/387 (32%), Positives = 186/387 (48%), Gaps = 6/387 (1%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDS 794 DF+ L +IG+G +G+V L + K+ + YA+K L+K +L+ + H+ AERN LL V Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAERNVLLKNVRH 93 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V L YSFQ E LY +++Y+ GG++ L R+ E A+FY AE AI +H Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSL 153 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 N I+RD+KP+N FGLCK EP+ T Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCK--------ECVEPEETTS------------- 192 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 + GTP+Y+APEVL K+ Y DWW LGA++YE Sbjct: 193 --------------------------TFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYE 226 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGA 1511 ML G PPF++ D I++ L+ P +++ DL+ LL + QRLG+K Sbjct: 227 MLHGLPPFFNTDVAQMYENILH--QPLQIPGGRTVAA--CDLLQGLLHKDQRQRLGSKED 282 Query: 1512 H-EIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWR 1682 +IK H +F + W+ LY ++ F P V G D ++F+ E T V S P Sbjct: 283 FLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDP-EFTQEAVSKSIGCTPDT 341 Query: 1683 KMLPS-KDANFVGYTYKNFEIVNDDEV 1760 S + F+G++Y +DD++ Sbjct: 342 VASSSGASSAFLGFSYAQ----DDDDI 364
>Q5F3L1:KS6A5_CHICK Ribosomal protein S6 kinase alpha-5 - Gallus gallus (Chicken)| Length = 789 Score = 174 bits (442), Expect = 1e-42 Identities = 119/360 (33%), Positives = 188/360 (52%), Gaps = 15/360 (4%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKLKKSEMLRRGQV-EHVKAER 770 K+G+E+FELL ++G GA+G+V L R+ + +YAMK LKK+ ++++ + EH + ER Sbjct: 33 KVGIENFELLKVLGTGAYGKVFLVRKVSGHDAGKLYAMKVLKKATIVQKAKTTEHTRTER 92 Query: 771 NLLAEV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETV 947 +L + S ++V L+Y+FQ D L+LI++Y+ GG++ T L +++ +E+E + YI E V Sbjct: 93 QVLEHIRQSPFLVTLHYAFQTDTKLHLILDYINGGELFTHLSQRERFSENEVQIYIGEIV 152 Query: 948 LAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAK 1127 LA+E +HK I+RDIK +N FGL K Sbjct: 153 LALEHLHKLGIIYRDIKLENILLDSDGHVVLTDFGLSKEF-------------------- 192 Query: 1128 PLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLL--KKGYGMEC 1301 L D R AYS GT +Y+AP+++ G+ Sbjct: 193 -LTDENER-------------------------AYSFCGTIEYMAPDIVRGGDTGHDKAV 226 Query: 1302 DWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVN--WRSHLKFPEEAKLSSETKDLISKLL 1475 DWWS+G +MYE+L G PF + ++ +I +S +P+E +S+ +KD+I +LL Sbjct: 227 DWWSVGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQE--MSALSKDIIQRLL 284 Query: 1476 C-NVEQRL--GTKGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNF-EKFEE 1637 + ++RL G A EIK H +F+ + W+ L K A F P + ELD NF E+F E Sbjct: 285 MKDPKKRLGCGPTDADEIKQHPFFQNINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTE 344 Score = 94.0 bits (232), Expect = 2e-18 Identities = 81/288 (28%), Positives = 119/288 (41%), Gaps = 9/288 (3%) Frame = +3 Query: 639 IGRGAFGEVRLCREKTSRSVYAMKKL-KKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLY 815 +G G+F R C K + YA+K + K+ E + ++ +K L E +VKL+ Sbjct: 422 LGEGSFSICRKCLHKKTSQEYAVKIISKRMEANTQREITALK-----LCE-GHPNVVKLH 475 Query: 816 YSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDI 995 + D +L+ME L GG+++ + +K +E EA + V A+ +H +HRD+ Sbjct: 476 EVYHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRLVSAVSHMHDVGVVHRDL 535 Query: 996 KPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNP-SAP 1172 KP+ NL D T K + +RL P + P Sbjct: 536 KPE---------------------------NLLFTDETDNSEIKIIDFGFARLKPPDNQP 568 Query: 1173 KRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYP 1352 +T T Y APE+ GY CD WSLG I+Y ML G Sbjct: 569 LKT------------------PCFTLHYAAPELFNHNGYDESCDLWSLGVILYTMLSGQV 610 Query: 1353 PFYSEDPMSTCRKIVNWRSHLK-----FPEEA--KLSSETKDLISKLL 1475 PF S+D TC + +K F EA +S E K+LI LL Sbjct: 611 PFQSQDKSLTCTSALEIMKKIKKGEFSFEGEAWKNVSEEAKELIQGLL 658
>Q21734:KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-1 - Caenorhabditis elegans| Length = 784 Score = 174 bits (442), Expect = 1e-42 Identities = 136/420 (32%), Positives = 203/420 (48%), Gaps = 14/420 (3%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKLKKSEMLRRGQVEHVKAERN 773 K FELL ++G+G+FG+V L R+ R VYAMK LKK+ + R + + K ERN Sbjct: 98 KADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR-QRTKLERN 156 Query: 774 LLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLA 953 +LA + +IVKL+Y+FQ + LYLI+++L GGD+ T L ++ TED+ KFY+AE LA Sbjct: 157 ILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLA 216 Query: 954 IESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 +E +H ++RD+KP+N FGL K S Sbjct: 217 LEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE------------------ 258 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 K+T YS GT +Y+APEV+ ++G+ M D+WS Sbjct: 259 -------------KKT----------------YSFCGTVEYMAPEVINRRGHSMAADFWS 289 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG +M+EML G+ PF D T +I+ ++ L P L+ E + L+ L N + Sbjct: 290 LGVLMFEMLTGHLPFQGRDRNDTMTQIL--KAKLSMPH--FLTQEAQSLLRALFKRNSQN 345 Query: 1491 RLGT--KGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSS 1664 RLG G EIK H +F + + KL +N E+D F+ + V S+S Sbjct: 346 RLGAGPDGVEEIKRHAFFAKIDFVKL----------LNKEID----PPFKPALSTVDSTS 391 Query: 1665 KAGP-----WRKMLPSKDANFVGY-TYKNFEIVNDDEVAGIAELKKKSSKSKR--PTIKT 1820 P K P+ A+ G+ ++ F V++ + E +K +KS R PT KT Sbjct: 392 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSN----AVMEERKLIAKSVRSVPTAKT 447 Score = 101 bits (252), Expect = 1e-20 Identities = 92/354 (25%), Positives = 154/354 (43%), Gaps = 5/354 (1%) Frame = +3 Query: 615 EDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS 794 +D+E+L IG GA V C+ K +R YA+K +KK+ +V+ LL Sbjct: 452 DDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVD------ILLRHSHH 505 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTL-TEDEAKFYIAETVLAIESIHK 971 ++VKL+ ++D+ +Y+I E GG+++ L+ K +L +E E +A + A++ +H Sbjct: 506 QFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHS 565 Query: 972 HNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSR 1151 HRD+ N F L K P ++ R Sbjct: 566 QQVAHRDLTAAN-----------ILFAL--------------------KDGDP---SSLR 591 Query: 1152 LTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 1331 + + K+++ E + + T ++APEVL K+GY CD WSLG +++ Sbjct: 592 IVDFGFAKQSRAE---------NGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLH 642 Query: 1332 EMLVGYPPFY---SEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGT 1502 ML G PF ++ P +++ + + + P +S E KDL+ K+L R T Sbjct: 643 TMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVT 702 Query: 1503 KGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVNGELDTQNFE-KFEETGAQVQSS 1661 A + H W +K E GELD QN + E+T + S+ Sbjct: 703 --AKQALQHKWI----GQKEALPDRPIQSEQVGELDMQNVKVALEQTYKAIASA 750
>Q60823:AKT2_MOUSE RAC-beta serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 481 Score = 174 bits (442), Expect = 1e-42 Identities = 112/348 (32%), Positives = 166/348 (47%), Gaps = 5/348 (1%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 R K+ + DF+ L ++G+G FG+V L REK + YAMK L+K ++ + +V H E + Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ L Y+FQ + L +MEY GG++ L R+ TED A+FY AE V A+ Sbjct: 204 LQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSAL 263 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLP 1136 E +H + ++RDIK +N FGLCK + + Sbjct: 264 EYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCK---------------------EGIS 302 Query: 1137 DNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSL 1316 D + T GTP+Y+APEVL YG DWW L Sbjct: 303 DGATMKT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWGL 336 Query: 1317 GAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQR 1493 G +MYEM+ G PFY++D I+ ++FP L E K L++ LL + +QR Sbjct: 337 GVVMYEMMCGRLPFYNQDHERLFELIL--MEEIRFPR--TLGPEAKSLLAGLLKKDPKQR 392 Query: 1494 L--GTKGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFE 1625 L G A E+ H +F + W+ + Q K F P+V E+DT+ F+ Sbjct: 393 LGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFD 440
>P31751:AKT2_HUMAN RAC-beta serine/threonine-protein kinase - Homo sapiens (Human)| Length = 481 Score = 174 bits (442), Expect = 1e-42 Identities = 112/348 (32%), Positives = 167/348 (47%), Gaps = 5/348 (1%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 R K+ + DF+ L ++G+G FG+V L REK + YAMK L+K ++ + +V H E + Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ L Y+FQ + L +MEY GG++ L R+ TE+ A+FY AE V A+ Sbjct: 204 LQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSAL 263 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLP 1136 E +H + ++RDIK +N FGLCK + + Sbjct: 264 EYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCK---------------------EGIS 302 Query: 1137 DNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSL 1316 D + T GTP+Y+APEVL YG DWW L Sbjct: 303 DGATMKT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWGL 336 Query: 1317 GAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQR 1493 G +MYEM+ G PFY++D I+ ++FP LS E K L++ LL + +QR Sbjct: 337 GVVMYEMMCGRLPFYNQDHERLFELIL--MEEIRFPR--TLSPEAKSLLAGLLKKDPKQR 392 Query: 1494 L--GTKGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFE 1625 L G A E+ H +F + W+ + Q K F P+V E+DT+ F+ Sbjct: 393 LGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFD 440
>P32023:KGP25_DROME cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 - Drosophila| melanogaster (Fruit fly) Length = 934 Score = 174 bits (441), Expect = 1e-42 Identities = 113/386 (29%), Positives = 186/386 (48%), Gaps = 17/386 (4%) Frame = +3 Query: 525 VPAEEQNNILKHLEKKETEYM---RLQRHKMGVE-------DFELLTIIGRGAFGEVRLC 674 + E N ++ +L++ + Y ++R K+ E D ++ +G G FG V L Sbjct: 581 IDRETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELV 640 Query: 675 REK--TSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYL 848 + +SRS +A+K++KKS+++ Q +H+ +E+ ++ E + +IVKL+ +F+D ++LY+ Sbjct: 641 QTNGDSSRS-FALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYM 699 Query: 849 IMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXX 1028 +ME GG++ T+L K + +FY A V A + +H N I+RD+KP+N Sbjct: 700 LMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERG 759 Query: 1029 XXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQ 1208 FG K L T R T Sbjct: 760 YVKLVDFGFAKKL------------------------QTGRKT----------------- 778 Query: 1209 KNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCR 1388 ++ GTP+Y+APEV+L +G+ + D+WSLG +M+E+L G PPF DPM T Sbjct: 779 -------WTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYN 831 Query: 1389 KIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTK--GAHEIKAHTWFRGVQWEK 1559 I+ ++FP ++ +LI KL N +RLG + G EI+ H WF G W Sbjct: 832 IILKGIDAIEFPR--NITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWG 889 Query: 1560 LYQ--MKAAFVPEVNGELDTQNFEKF 1631 L ++ P V +DT NF+ + Sbjct: 890 LQNCTLEPPIKPAVKSVVDTTNFDDY 915
>Q03043:KGP24_DROME cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B -| Drosophila melanogaster (Fruit fly) Length = 1088 Score = 174 bits (441), Expect = 1e-42 Identities = 113/386 (29%), Positives = 186/386 (48%), Gaps = 17/386 (4%) Frame = +3 Query: 525 VPAEEQNNILKHLEKKETEYM---RLQRHKMGVE-------DFELLTIIGRGAFGEVRLC 674 + E N ++ +L++ + Y ++R K+ E D ++ +G G FG V L Sbjct: 735 IDRETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELV 794 Query: 675 REK--TSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYL 848 + +SRS +A+K++KKS+++ Q +H+ +E+ ++ E + +IVKL+ +F+D ++LY+ Sbjct: 795 QTNGDSSRS-FALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYM 853 Query: 849 IMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXX 1028 +ME GG++ T+L K + +FY A V A + +H N I+RD+KP+N Sbjct: 854 LMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERG 913 Query: 1029 XXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQ 1208 FG K L T R T Sbjct: 914 YVKLVDFGFAKKL------------------------QTGRKT----------------- 932 Query: 1209 KNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCR 1388 ++ GTP+Y+APEV+L +G+ + D+WSLG +M+E+L G PPF DPM T Sbjct: 933 -------WTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYN 985 Query: 1389 KIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTK--GAHEIKAHTWFRGVQWEK 1559 I+ ++FP ++ +LI KL N +RLG + G EI+ H WF G W Sbjct: 986 IILKGIDAIEFPR--NITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWG 1043 Query: 1560 LYQ--MKAAFVPEVNGELDTQNFEKF 1631 L ++ P V +DT NF+ + Sbjct: 1044 LQNCTLEPPIKPAVKSVVDTTNFDDY 1069
>P31750:AKT1_MOUSE RAC-alpha serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 480 Score = 174 bits (440), Expect = 2e-42 Identities = 116/358 (32%), Positives = 174/358 (48%), Gaps = 6/358 (1%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 +H++ + +FE L ++G+G FG+V L +EK + YAMK LKK ++ + +V H E + Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ L YSFQ + L +MEY GG++ L R+ +ED A+FY AE V A+ Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 261 Query: 957 ESIH-KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 + +H + N ++RD+K +N FGLCK + + Sbjct: 262 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCK---------------------EGI 300 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 D + T GTP+Y+APEVL YG DWW Sbjct: 301 KDGATMKT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWG 334 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG +MYEM+ G PFY++D I+ + FP L E K L+S LL + Q Sbjct: 335 LGVVMYEMMCGRLPFYNQDHEKLFELIL--MEEIAFPR--TLGPEAKSLLSGLLKKDPTQ 390 Query: 1491 RL--GTKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQV 1652 RL G++ A EI H +F + W+ +Y+ K + F P+V E DT+ F+ EE AQ+ Sbjct: 391 RLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFD--EEFTAQM 446
>Q5R4K3:KS6A5_PONPY Ribosomal protein S6 kinase alpha-5 - Pongo pygmaeus (Orangutan)| Length = 802 Score = 173 bits (439), Expect = 2e-42 Identities = 134/447 (29%), Positives = 213/447 (47%), Gaps = 17/447 (3%) Frame = +3 Query: 567 KKETEYMRLQRH--KMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKLKKSEM 731 K E L H ++G+E+FELL ++G GA+G+V L R+ + +YAMK LKK+ + Sbjct: 29 KHELRTANLTGHAERVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATI 88 Query: 732 LRRGQV-EHVKAERNLLAEV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDT 905 +++ + EH + ER +L S ++V L+Y+FQ + L+LI++Y+ GG++ T L +++ Sbjct: 89 VQKAKTTEHTRTERQVLEHTRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRER 148 Query: 906 LTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFP 1085 TE E + Y+ E VLA+E +HK I+RDIK +N FGL K Sbjct: 149 FTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVMLTDFGLSKEF------ 202 Query: 1086 NLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAP 1265 + D T R AYS GT +Y+AP Sbjct: 203 ---------------VADETER-------------------------AYSFCGTIEYMAP 222 Query: 1266 EVLL--KKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVN--WRSHLKFPEEA 1433 +++ G+ DWWSLG +MYE+L G PF + ++ +I +S +P+E Sbjct: 223 DIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQE- 281 Query: 1434 KLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVN 1598 +S+ KDLI LL + ++RL G + A EIK H +F+ + W+ L K A F P + Sbjct: 282 -MSALAKDLIQHLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIR 340 Query: 1599 GELDTQNF-EKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAE 1775 ELD NF E+F E ++ + S + F GY++ I+ A I Sbjct: 341 DELDVSNFAEEFTEMDPTYSPAA-------LPQSSEKLFQGYSFVAPSILFKRNAAVIDP 393 Query: 1776 LKKKSSKSKRPTIKTLFESMDEDEPVH 1856 L+ + +M +D P + Sbjct: 394 LQFHMEVERPGVTNVARSAMMKDSPFY 420 Score = 100 bits (250), Expect = 2e-20 Identities = 90/325 (27%), Positives = 131/325 (40%), Gaps = 7/325 (2%) Frame = +3 Query: 522 EVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVY 701 EV N+ + K++ + Q + + ++D L G G+F R C K S + Sbjct: 399 EVERPGVTNVARSAMMKDSPFY--QHYDLDLKDKPL----GEGSFSICRKCVHKKSNQAF 452 Query: 702 AMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMM 881 A+K + K R + K L IVKL+ F D +L+ME L GG++ Sbjct: 453 AVKIISK-----RMEANTQKEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELF 507 Query: 882 TLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCK 1061 + +K +E EA + + + V A+ +H +HRD+KP+N Sbjct: 508 ERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLF--------------- 552 Query: 1062 PLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTV 1241 D ++ + D+ A+P P + L P Sbjct: 553 -TDENDNLEIKIIDF---GFARPKPPDNQPLKTPCF------------------------ 584 Query: 1242 GTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLK- 1418 T Y APE+L + GY CD WSLG I+Y ML G PF S D TC V +K Sbjct: 585 -TLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKK 643 Query: 1419 ----FPEEA--KLSSETKDLISKLL 1475 F EA +S E KDLI LL Sbjct: 644 GDFSFEGEAWKNVSQEAKDLIQGLL 668
>Q16513:PKN2_HUMAN Serine/threonine-protein kinase N2 - Homo sapiens (Human)| Length = 984 Score = 173 bits (438), Expect = 3e-42 Identities = 120/399 (30%), Positives = 185/399 (46%), Gaps = 28/399 (7%) Frame = +3 Query: 513 QDAEVPAEEQNNILKHLEKKETEYM--------------------RLQRHKMGVEDFELL 632 QD+E + QN+ L K ++EY QR + ++DF Sbjct: 601 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC 660 Query: 633 TIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA---YI 803 ++GRG FG+V L K + ++A+K LKK +++ R +V+ + E+ + V+S ++ Sbjct: 661 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL 720 Query: 804 VKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYI 983 V L+ FQ E + +MEY GGD+M + + D +E A FY A VL ++ +H+H + Sbjct: 721 VNLFACFQTKEHVCFVMEYAAGGDLM-MHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIV 779 Query: 984 HRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNP 1163 +RD+K DN FGLCK G G D TS Sbjct: 780 YRDLKLDNLLLDTEGFVKIADFGLCK----------------EGMG---YGDRTS----- 815 Query: 1164 SAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLV 1343 + GTP+++APEVL + Y DWW LG ++YEMLV Sbjct: 816 -----------------------TFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLV 852 Query: 1344 GYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT--KGAH 1514 G PF +D IVN +++P LS+E ++ +LL N E+RLG K A Sbjct: 853 GESPFPGDDEEEVFDSIVN--DEVRYPR--FLSTEAISIMRRLLRRNPERRLGASEKDAE 908 Query: 1515 EIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFE 1625 ++K H +FR + W L ++K F+P + G D NF+ Sbjct: 909 DVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFD 947
>O75676:KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 - Homo sapiens (Human)| Length = 772 Score = 172 bits (437), Expect = 4e-42 Identities = 140/478 (29%), Positives = 226/478 (47%), Gaps = 13/478 (2%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKLKKSEMLRRGQV-EHVKAER 770 K+ VE+FELL ++G GA+G+V L R+ +YAMK L+K+ +++R + EH + ER Sbjct: 27 KVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTER 86 Query: 771 NLLAEVDSA-YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETV 947 ++L V A ++V L+Y+FQ D L+LI++Y+ GG+M T L ++ E E + Y E V Sbjct: 87 SVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIV 146 Query: 948 LAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAK 1127 LA+E +HK I+RD+K +N FGL K L E Sbjct: 147 LALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEF-------LTE---------- 189 Query: 1128 PLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKK-GYGMECD 1304 +K R +S GT +Y+APE++ K G+G D Sbjct: 190 --------------------------EKER---TFSFCGTIEYMAPEIIRSKTGHGKAVD 220 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WWSLG +++E+L G PF E +T ++ P ++ +DL+ +LLC + Sbjct: 221 WWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKD 280 Query: 1482 VEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKFEETGAQ 1649 ++RLG +GA E++ H +F+G+ W L K A F P++ ELD NF + E T + Sbjct: 281 PKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAE-EFTRLE 339 Query: 1650 VQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAELKKKSSKSKRPTIKTLFE 1829 S P P F GY++ I+ D A + + + RP + Sbjct: 340 PVYSPPGSP----PPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVAR 395 Query: 1830 S-MDEDEPVHGSF-LNMLPHKEGQPSSHSSAPPEQYQPRRK*DMEVLKSKPQKSKREE 1997 S M +D P + L++ GQ S Q Q ++ +++L + + + + E Sbjct: 396 SAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQRE 453 Score = 85.9 bits (211), Expect = 6e-16 Identities = 84/313 (26%), Positives = 129/313 (41%), Gaps = 12/313 (3%) Frame = +3 Query: 639 IGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYY 818 +G+G+F R CR++ S +A+K L S L V A R + + +V L+ Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKIL--SRRLEANTQREVAALRLCQSHPN---VVNLHE 471 Query: 819 SFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH-NYIHRDI 995 D YL++E L GG+++ + +K +E EA + V A+ +H+ +HRD+ Sbjct: 472 VHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDL 531 Query: 996 KPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLT--NPSA 1169 KP+N D TPG K + +RL +P Sbjct: 532 KPENILYA---------------------------DDTPGAPVKIIDFGFARLRPQSPGV 564 Query: 1170 PKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGY 1349 P +T T Y APE+L ++GY CD WSLG I+Y ML G Sbjct: 565 PMQTP------------------CFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQ 606 Query: 1350 PPF--------YSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT 1502 PF S+ C KI R L +S E K+L+ LL + +RL Sbjct: 607 VPFQGASGQGGQSQAAEIMC-KIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKL 665 Query: 1503 KGAHEIKAHTWFR 1541 +G ++ +W + Sbjct: 666 EG---LRGSSWLQ 675
>P70268:PKN1_MOUSE Serine/threonine-protein kinase N1 - Mus musculus (Mouse)| Length = 946 Score = 172 bits (436), Expect = 5e-42 Identities = 120/387 (31%), Positives = 189/387 (48%), Gaps = 8/387 (2%) Frame = +3 Query: 591 LQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAER 770 L++ + +EDF+ L ++GRG FG+V L ++S ++A+K LKK +++ R +VE + E+ Sbjct: 609 LRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEK 668 Query: 771 NLLAEVDSA---YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAE 941 +LA V A ++V L+ FQ E + +MEY GGD+M L + D +E A FY A Sbjct: 669 RILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAVFYSAC 727 Query: 942 TVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKG 1121 VL ++ +H+H ++RD+K DN FGLCK G G Sbjct: 728 VVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCK----------------EGMG 771 Query: 1122 AKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMEC 1301 D TS + GTP+++APEVL Y Sbjct: 772 ---YGDRTS----------------------------TFCGTPEFLAPEVLTDTSYTRAV 800 Query: 1302 DWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-C 1478 DWW LG ++YEMLVG PF +D IVN +++P LS+E ++ +LL Sbjct: 801 DWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVN--DEVRYPR--FLSAEAIGIMRRLLRR 856 Query: 1479 NVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKFEETGA 1646 N E+RLG+ + A ++K +FR + W+ L ++ FVP ++G D NF+ EE Sbjct: 857 NPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPPFVPTLSGRTDVSNFD--EEFTG 914 Query: 1647 QVQSSSKAGPWRKMLPSKDANFVGYTY 1727 + + S R + ++ A F + + Sbjct: 915 EAPTLSPPRDARPLTAAEQAAFRDFDF 941
>P47197:AKT2_RAT RAC-beta serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 481 Score = 171 bits (434), Expect = 8e-42 Identities = 112/348 (32%), Positives = 165/348 (47%), Gaps = 5/348 (1%) Frame = +3 Query: 597 RHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNL 776 R K+ + DF+ L ++G+G FG+V L REK + YAMK L+K ++ + +V H E + Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203 Query: 777 LAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 L ++ L Y+FQ + L +MEY GGD+ L R+ TED A+FY AE V A+ Sbjct: 204 LQNTRHPFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSAL 263 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLP 1136 E +H + ++RDIK +N FGL K + + Sbjct: 264 EYLHSTDVVYRDIKLENLMLDKDGHIKITDFGLSK---------------------EGIS 302 Query: 1137 DNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSL 1316 D + T GTP+Y+APEVL YG DWW L Sbjct: 303 DGATMKT--------------------------FCGTPEYLAPEVLEDNDYGRAVDWWGL 336 Query: 1317 GAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQR 1493 G +MYEM+ G PFY++D I+ ++FP L E K L++ LL + +QR Sbjct: 337 GVVMYEMMCGRLPFYNQDHERLFELIL--MEEIRFPR--TLGPEAKSLLAGLLKKDPKQR 392 Query: 1494 L--GTKGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFE 1625 L G A E+ H +F + W+ + Q K F P+V E+DT+ F+ Sbjct: 393 LGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFD 440
>O08874:PKN2_RAT Serine/threonine-protein kinase N2 - Rattus norvegicus (Rat)| Length = 985 Score = 171 bits (432), Expect = 1e-41 Identities = 115/363 (31%), Positives = 175/363 (48%), Gaps = 8/363 (2%) Frame = +3 Query: 561 LEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRR 740 LE K ++ QR + ++DF ++GRG FG+V L K + ++A+K LKK +++ R Sbjct: 642 LEDKRSQ----QRFQFNLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVAR 697 Query: 741 GQVEHVKAERNLLAEVDSA---YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLT 911 +V+ + E+ + V+S ++V L+ FQ E + +MEY GGD+M + + D + Sbjct: 698 DEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLM-MHIHTDVFS 756 Query: 912 EDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNL 1091 E A FY A VL ++ +H+H ++RD+K DN FGLCK Sbjct: 757 EPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEASVKIADFGLCK---------- 806 Query: 1092 NEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEV 1271 G G D TS + GTP+++APEV Sbjct: 807 ------EGMG---YGDRTS----------------------------TFCGTPEFLAPEV 829 Query: 1272 LLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSET 1451 L + Y DWW LG ++YEMLVG PF +D IVN +++P LS+E Sbjct: 830 LTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVN--DEVRYPR--FLSTEA 885 Query: 1452 KDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQ 1616 ++ +LL N E+RLG K A ++K H +FR W L ++K FVP + G D Sbjct: 886 ISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALLDKKVKPPFVPTIRGREDVS 945 Query: 1617 NFE 1625 NF+ Sbjct: 946 NFD 948
>Q63433:PKN1_RAT Serine/threonine-protein kinase N1 - Rattus norvegicus (Rat)| Length = 946 Score = 171 bits (432), Expect = 1e-41 Identities = 120/387 (31%), Positives = 187/387 (48%), Gaps = 8/387 (2%) Frame = +3 Query: 591 LQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAER 770 L++ + +EDF+ L ++GRG FG+V L +S ++A+K LKK +++ R +VE + E+ Sbjct: 609 LRKSPLTLEDFKFLAVLGRGHFGKVLLSEFHSSGELFAIKALKKGDIVARDEVESLMCEK 668 Query: 771 NLLAEVDSA---YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAE 941 +LA V A ++V L+ FQ E + +MEY GGD+M L + D +E A FY A Sbjct: 669 RILATVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAGFYSAC 727 Query: 942 TVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKG 1121 VL ++ +H+H ++RD+K DN FGLCK G G Sbjct: 728 VVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCK----------------EGMG 771 Query: 1122 AKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMEC 1301 D TS + GTP+++APEVL Y Sbjct: 772 ---YGDRTS----------------------------TFCGTPEFLAPEVLTDTSYTRAV 800 Query: 1302 DWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-C 1478 DWW LG +YEMLVG PF +D IVN +++P LS+E ++ +LL Sbjct: 801 DWWGLGVFLYEMLVGESPFPGDDEEEVFDSIVN--DEVRYPR--FLSAEAIGIMRRLLRR 856 Query: 1479 NVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKFEETGA 1646 N E+RLG+ + A ++K +FR + W+ L ++ FVP ++G D NF+ EE Sbjct: 857 NPERRLGSTERDAEDVKKQPFFRTLDWDALLARRLPPPFVPTLSGRTDVSNFD--EEFTG 914 Query: 1647 QVQSSSKAGPWRKMLPSKDANFVGYTY 1727 + + S R + ++ A F + + Sbjct: 915 EAPTLSPPRDARPLTAAEQAAFRDFDF 941
>Q64595:KGP2_RAT cGMP-dependent protein kinase 2 - Rattus norvegicus (Rat)| Length = 762 Score = 171 bits (432), Expect = 1e-41 Identities = 116/410 (28%), Positives = 193/410 (47%), Gaps = 8/410 (1%) Frame = +3 Query: 426 KQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHK 605 ++Y+E + T + + R +R M KL A + + L++K + Sbjct: 398 QKYLEGYVATLNRDDEKRHAKRSMSSWKLSKA------LSLEMIQLKEKVARFSSTSPF- 450 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 ++ E++ +G G FG V L + K +AMK ++K ++ Q EHV +E+ +L E Sbjct: 451 ---QNLEIIATLGVGGFGRVELVKVKNENIAFAMKCIRKKHIVDTKQQEHVYSEKRILEE 507 Query: 786 VDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESI 965 + S +IVKLY +F+D++++Y+++E GG++ ++L + + E +KF +A A + + Sbjct: 508 LCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYL 567 Query: 966 HKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNT 1145 H+ I+RD+KP+N FG K + G G K Sbjct: 568 HRLGIIYRDLKPENLILDADGYLKLVDFGFAKKI---------------GSGQK------ 606 Query: 1146 SRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAI 1325 ++ GTP+Y+APEV+L KG+ D+WSLG + Sbjct: 607 ---------------------------TWTFCGTPEYVAPEVILNKGHDFSVDFWSLGIL 639 Query: 1326 MYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT 1502 +YE+L G PPF D M T I+ + FP K++ +DLI +L N +RLG Sbjct: 640 VYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPR--KITRRPEDLIRRLCRQNPTERLGN 697 Query: 1503 --KGAHEIKAHTWFRGVQWEKLYQMKAAFVP-----EVNGELDTQNFEKF 1631 G ++IK H W G WE L KA +P E++G +D F+K+ Sbjct: 698 LKNGINDIKKHRWLNGFNWEGL---KARSLPSPLRRELSGPIDHSYFDKY 744
>P49673:KAPC_ASCSU cAMP-dependent protein kinase catalytic subunit - Ascaris suum (Pig| roundworm) (Ascaris lumbricoides) Length = 337 Score = 171 bits (432), Expect = 1e-41 Identities = 104/351 (29%), Positives = 164/351 (46%), Gaps = 5/351 (1%) Frame = +3 Query: 600 HKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLL 779 +K+ V+DF+ + IG G+FG V L + + S +A+KK+ E++ Q EHV +E+ LL Sbjct: 22 NKLNVDDFDRICTIGTGSFGRVYLVQHRASEQYFALKKMAIREVVSMRQTEHVHSEKRLL 81 Query: 780 AEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 + + +IVK+Y + D LY++ EYL GG++ + L T + A+FY AE V A++ Sbjct: 82 SRLSHPFIVKMYCASWDKYNLYMLFEYLAGGELFSYLRASRTFSNSMARFYAAEIVCALQ 141 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPD 1139 +H N +RD+KP+N FG K + + P+Y Sbjct: 142 YLHSKNIAYRDLKPENLMLNKEGHLKMTDFGFAKEVIDRTWTMCGTPEY----------- 190 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLG 1319 +APEV+ KG+ DWWSLG Sbjct: 191 ---------------------------------------LAPEVIGNKGHDTAVDWWSLG 211 Query: 1320 AIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRL 1496 ++YEM++G PPF + KI+ L+F L + KDL+ KLL + QRL Sbjct: 212 VLIYEMMIGIPPFRGKTLDEIYEKII--LGKLRFTRSFDLFA--KDLVKKLLQVDRTQRL 267 Query: 1497 GTK--GAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEE 1637 G + GA ++ H WF + W+ + MK +P + DT NF+ ++E Sbjct: 268 GNQKDGAADVMNHKWFTDIDWDDVQNMKLTPPIIPTLYSNGDTGNFDSYDE 318
>Q8BWW9:PKN2_MOUSE Serine/threonine-protein kinase N2 - Mus musculus (Mouse)| Length = 983 Score = 170 bits (431), Expect = 2e-41 Identities = 112/352 (31%), Positives = 170/352 (48%), Gaps = 8/352 (2%) Frame = +3 Query: 594 QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN 773 QR + ++DF ++GRG FG+V L K + ++A+K LKK +++ R +V+ + E+ Sbjct: 647 QRFQFSLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKR 706 Query: 774 LLAEVDSA---YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 + V+S ++V L+ FQ E + +MEY GGD+M + + D +E A FY A Sbjct: 707 IFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLM-MHIHTDVFSEPRAVFYAACV 765 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 VL ++ +H+H ++RD+K DN FGLCK G G Sbjct: 766 VLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCK----------------EGMG- 808 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 D TS + GTP+++APEVL + Y D Sbjct: 809 --YGDRTS----------------------------TFCGTPEFLAPEVLTETSYTRAVD 838 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CN 1481 WW LG ++YEMLVG PF +D IVN +++P LS+E ++ +LL N Sbjct: 839 WWGLGVLIYEMLVGESPFPGDDEEEVFDSIVN--DEVRYPR--FLSTEAISIMRRLLRRN 894 Query: 1482 VEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFE 1625 E+RLG K A ++K H +FR W L ++K FVP + G D NF+ Sbjct: 895 PERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFD 946
>Q13237:KGP2_HUMAN cGMP-dependent protein kinase 2 - Homo sapiens (Human)| Length = 762 Score = 170 bits (431), Expect = 2e-41 Identities = 102/344 (29%), Positives = 167/344 (48%), Gaps = 5/344 (1%) Frame = +3 Query: 615 EDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS 794 ++ E++ +G G FG V L + K +AMK ++K ++ Q EHV +E+ +L E+ S Sbjct: 451 QNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS 510 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 +IVKLY +F+D++++Y+++E GG++ ++L + + E +KF +A A + +H+ Sbjct: 511 PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRL 570 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 I+RD+KP+N FG K + G G K Sbjct: 571 GIIYRDLKPENLILDAEGYLKLVDFGFAKKI---------------GSGQK--------- 606 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 ++ GTP+Y+APEV+L KG+ D+WSLG ++YE Sbjct: 607 ------------------------TWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYE 642 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT--K 1505 +L G PPF D M T I+ + FP K++ +DLI +L N +RLG Sbjct: 643 LLTGNPPFSGVDQMMTYNLILKGIEKMDFPR--KITRRPEDLIRRLCRQNPTERLGNLKN 700 Query: 1506 GAHEIKAHTWFRGVQWE--KLYQMKAAFVPEVNGELDTQNFEKF 1631 G ++IK H W G WE K + + E+ G +D F+K+ Sbjct: 701 GINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKY 744
>Q5R7A7:SGK3_PONPY Serine/threonine-protein kinase Sgk3 - Pongo pygmaeus (Orangutan)| Length = 496 Score = 170 bits (430), Expect = 2e-41 Identities = 118/377 (31%), Positives = 174/377 (46%), Gaps = 7/377 (1%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDS 794 DF+ L +IG+G+FG+V L + K YA+K L+K +L R + +H+ AERN LL V Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V L+YSFQ E LY +++++ GG++ L R+ + E A+FY AE A+ +H Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 ++RD+KP+N FGLCK + D T+ Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKE-------------------GIAISDTTT-- 319 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 + GTP+Y+APEV+ K+ Y DWW LGA++YE Sbjct: 320 --------------------------TFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYE 353 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAH 1514 ML G PPFY D I++ L+ S ++L+ K + + RLG K Sbjct: 354 MLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEK---DRQNRLGAKEDF 410 Query: 1515 -EIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKF---EETGAQVQSSSKAGP 1676 EI+ H +F + W L Q K F P V G D +NF+ E V SS Sbjct: 411 LEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSI 470 Query: 1677 WRKMLPSKDANFVGYTY 1727 + D FVG++Y Sbjct: 471 VNASVLEADDAFVGFSY 487
>Q96BR1:SGK3_HUMAN Serine/threonine-protein kinase Sgk3 - Homo sapiens (Human)| Length = 496 Score = 170 bits (430), Expect = 2e-41 Identities = 118/377 (31%), Positives = 174/377 (46%), Gaps = 7/377 (1%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEVDS 794 DF+ L +IG+G+FG+V L + K YA+K L+K +L R + +H+ AERN LL V Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V L+YSFQ E LY +++++ GG++ L R+ + E A+FY AE A+ +H Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 ++RD+KP+N FGLCK + D T+ Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKE-------------------GIAISDTTT-- 319 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 + GTP+Y+APEV+ K+ Y DWW LGA++YE Sbjct: 320 --------------------------TFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYE 353 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKGAH 1514 ML G PPFY D I++ L+ S ++L+ K + + RLG K Sbjct: 354 MLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEK---DRQNRLGAKEDF 410 Query: 1515 -EIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKF---EETGAQVQSSSKAGP 1676 EI+ H +F + W L Q K F P V G D +NF+ E V SS Sbjct: 411 LEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSI 470 Query: 1677 WRKMLPSKDANFVGYTY 1727 + D FVG++Y Sbjct: 471 VNASVLEADDAFVGFSY 487
>Q61410:KGP2_MOUSE cGMP-dependent protein kinase 2 - Mus musculus (Mouse)| Length = 762 Score = 169 bits (428), Expect = 4e-41 Identities = 116/410 (28%), Positives = 192/410 (46%), Gaps = 8/410 (1%) Frame = +3 Query: 426 KQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHK 605 ++Y+E + T + + R +R M KL A + + L++K + Sbjct: 398 QKYLEGYVATLNRDDEKRHAKRSMSSWKLSKA------LSLEMIQLKEKVARFSSTSPF- 450 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 ++ E++ +G G FG V L + K +AMK ++K ++ Q EHV +E+ +L E Sbjct: 451 ---QNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEE 507 Query: 786 VDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESI 965 + S +IVKLY +F+D++++Y+++E GG++ ++L + + E +KF +A A + + Sbjct: 508 LCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYL 567 Query: 966 HKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNT 1145 H I+RD+KP+N FG K + G G K Sbjct: 568 HLLGIIYRDLKPENLILDADGYLKLVDFGFAKKI---------------GSGQK------ 606 Query: 1146 SRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAI 1325 ++ GTP+Y+APEV+L KG+ D+WSLG + Sbjct: 607 ---------------------------TWTFCGTPEYVAPEVILNKGHDFSVDFWSLGIL 639 Query: 1326 MYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT 1502 +YE+L G PPF D M T I+ + FP K++ +DLI +L N +RLG Sbjct: 640 VYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPR--KITRRPEDLIRRLCRQNPTERLGN 697 Query: 1503 --KGAHEIKAHTWFRGVQWEKLYQMKAAFVP-----EVNGELDTQNFEKF 1631 G ++IK H W G WE L KA +P E++G +D F+K+ Sbjct: 698 LKNGINDIKKHRWLNGFNWEGL---KARSLPSPLRRELSGPIDHSYFDKY 744
>P17252:KPCA_HUMAN Protein kinase C alpha type - Homo sapiens (Human)| Length = 672 Score = 168 bits (426), Expect = 7e-41 Identities = 122/430 (28%), Positives = 206/430 (47%), Gaps = 7/430 (1%) Frame = +3 Query: 480 KERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFG 659 +E L +K + A++ N ++ E ++ L R K+ DF L ++G+G+FG Sbjct: 295 EEGNMELRQKFEKAKL-GPAGNKVISPSEDRKQPSNNLDRVKL--TDFNFLMVLGKGSFG 351 Query: 660 EVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA-YIVKLYYSFQDDE 836 +V L K + +YA+K LKK +++ VE E+ +LA +D ++ +L+ FQ + Sbjct: 352 KVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVD 411 Query: 837 FLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXX 1016 LY +MEY+ GGD+M + + E +A FY AE + + +HK I+RD+K DN Sbjct: 412 RLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVML 471 Query: 1017 XXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQL 1196 FG+CK + + D + T Sbjct: 472 DSEGHIKIADFGMCK---------------------EHMMDGVTTRT------------- 497 Query: 1197 SHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPM 1376 GTPDYIAPE++ + YG DWW+ G ++YEML G PPF ED Sbjct: 498 -------------FCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDED 544 Query: 1377 STCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWFRGV 1547 + I+ ++ +P+ LS E + L+ + +RL G +G +++ H +FR + Sbjct: 545 ELFQSIM--EHNVSYPK--SLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRI 600 Query: 1548 QWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKD-ANFVG 1718 WEKL +++ F P+V G+ +NF+KF G V + P + ++ + D ++F G Sbjct: 601 DWEKLENREIQPPFKPKVCGK-GAENFDKFFTRGQPVLTP----PDQLVIANIDQSDFEG 655 Query: 1719 YTYKNFEIVN 1748 ++Y N + V+ Sbjct: 656 FSYVNPQFVH 665
>P05696:KPCA_RAT Protein kinase C alpha type - Rattus norvegicus (Rat)| Length = 672 Score = 168 bits (425), Expect = 9e-41 Identities = 121/424 (28%), Positives = 204/424 (48%), Gaps = 7/424 (1%) Frame = +3 Query: 498 LERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCR 677 L +K + A++ N ++ E ++ L R K+ DF L ++G+G+FG+V L Sbjct: 301 LRQKFEKAKL-GPAGNKVISPSEDRKQPSNNLDRVKL--TDFNFLMVLGKGSFGKVMLAD 357 Query: 678 EKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA-YIVKLYYSFQDDEFLYLIM 854 K + +YA+K LKK +++ VE E+ +LA +D ++ +L+ FQ + LY +M Sbjct: 358 RKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVM 417 Query: 855 EYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXX 1034 EY+ GGD+M + + E +A FY AE + + +HK I+RD+K DN Sbjct: 418 EYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHI 477 Query: 1035 XXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKN 1214 FG+CK + + D + T Sbjct: 478 KIADFGMCK---------------------EHMMDGVTTRT------------------- 497 Query: 1215 RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKI 1394 GTPDYIAPE++ + YG DWW+ G ++YEML G PPF ED + I Sbjct: 498 -------FCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSI 550 Query: 1395 VNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWFRGVQWEKL- 1562 + ++ +P+ LS E + L+ + +RL G +G +++ H +FR + WEKL Sbjct: 551 M--EHNVSYPK--SLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLE 606 Query: 1563 -YQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKD-ANFVGYTYKNF 1736 +++ F P+V G+ +NF+KF G V + P + ++ + D ++F G++Y N Sbjct: 607 NREIQPPFKPKVCGK-GAENFDKFFTRGQPVLTP----PDQLVIANIDQSDFEGFSYVNP 661 Query: 1737 EIVN 1748 + V+ Sbjct: 662 QFVH 665
>P10102:KPCA_RABIT Protein kinase C alpha type - Oryctolagus cuniculus (Rabbit)| Length = 672 Score = 168 bits (425), Expect = 9e-41 Identities = 121/424 (28%), Positives = 204/424 (48%), Gaps = 7/424 (1%) Frame = +3 Query: 498 LERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCR 677 L +K + A++ N ++ E ++ L R K+ DF L ++G+G+FG+V L Sbjct: 301 LRQKFEKAKL-GPAGNKVISPSEDRKQPSNNLDRVKL--TDFNFLMVLGKGSFGKVMLAD 357 Query: 678 EKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA-YIVKLYYSFQDDEFLYLIM 854 K + +YA+K LKK +++ VE E+ +LA +D ++ +L+ FQ + LY +M Sbjct: 358 RKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALMDKPPFLTQLHSCFQTVDRLYFVM 417 Query: 855 EYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXX 1034 EY+ GGD+M + + E +A FY AE + + +HK I+RD+K DN Sbjct: 418 EYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHI 477 Query: 1035 XXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKN 1214 FG+CK + + D + T Sbjct: 478 KIADFGMCK---------------------EHMMDGVTTRT------------------- 497 Query: 1215 RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKI 1394 GTPDYIAPE++ + YG DWW+ G ++YEML G PPF ED + I Sbjct: 498 -------FCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSI 550 Query: 1395 VNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWFRGVQWEKL- 1562 + ++ +P+ LS E + L+ + +RL G +G +++ H +FR + WEKL Sbjct: 551 M--EHNVSYPK--SLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLE 606 Query: 1563 -YQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKD-ANFVGYTYKNF 1736 +++ F P+V G+ +NF+KF G V + P + ++ + D ++F G++Y N Sbjct: 607 NREIQPPFKPKVCGK-GAENFDKFFTRGQPVVTP----PDQLVIANIDQSDFEGFSYVNP 661 Query: 1737 EIVN 1748 + V+ Sbjct: 662 QFVH 665
>P34885:KPC1B_CAEEL Protein kinase C-like 1B - Caenorhabditis elegans| Length = 707 Score = 168 bits (425), Expect = 9e-41 Identities = 104/348 (29%), Positives = 167/348 (47%), Gaps = 8/348 (2%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA- 782 + + DF + ++G+G+FG+V L K + VYA+K LKK +++ VE E+ +L+ Sbjct: 373 LSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSL 432 Query: 783 EVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 ++ L+ SFQ + L+ +MEY+ GGD+M + R E A+FY AE A++ Sbjct: 433 AAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQF 492 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H+++ I+RD+K DN FG+CK + N NL Sbjct: 493 LHRNDVIYRDLKLDNILLDAEGHCRLADFGMCK--EGINKDNLTS--------------- 535 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 + GTPDYIAPE+L + YG+ DWW+LG Sbjct: 536 ------------------------------TFCGTPDYIAPEILQEMEYGVSVDWWALGV 565 Query: 1323 IMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRLG 1499 +MYEM+ G PPF +++ I+N + +P LS E +++ + N +RLG Sbjct: 566 LMYEMMAGQPPFEADNEDDLFEAILN--DDVLYP--VWLSKEAVNILKAFMTKNAGKRLG 621 Query: 1500 ----TKGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFE 1625 G I+AH +FR + W+ L Q+K F P++ + D NF+ Sbjct: 622 CVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFD 669
>P04409:KPCA_BOVIN Protein kinase C alpha type - Bos taurus (Bovine)| Length = 672 Score = 167 bits (423), Expect = 2e-40 Identities = 121/424 (28%), Positives = 203/424 (47%), Gaps = 7/424 (1%) Frame = +3 Query: 498 LERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCR 677 L +K + A++ N ++ E + L R K+ DF L ++G+G+FG+V L Sbjct: 301 LRQKFEKAKL-GPAGNKVISPSEDRRQPSNNLDRVKL--TDFNFLMVLGKGSFGKVMLAD 357 Query: 678 EKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA-YIVKLYYSFQDDEFLYLIM 854 K + +YA+K LKK +++ VE E+ +LA +D ++ +L+ FQ + LY +M Sbjct: 358 RKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVM 417 Query: 855 EYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXX 1034 EY+ GGD+M + + E +A FY AE + + +HK I+RD+K DN Sbjct: 418 EYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHI 477 Query: 1035 XXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKN 1214 FG+CK + + D + T Sbjct: 478 KIADFGMCK---------------------EHMMDGVTTRT------------------- 497 Query: 1215 RRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKI 1394 GTPDYIAPE++ + YG DWW+ G ++YEML G PPF ED + I Sbjct: 498 -------FCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSI 550 Query: 1395 VNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWFRGVQWEKL- 1562 + ++ +P+ LS E + L+ + +RL G +G +++ H +FR + WEKL Sbjct: 551 M--EHNVSYPK--SLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDWEKLE 606 Query: 1563 -YQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKD-ANFVGYTYKNF 1736 +++ F P+V G+ +NF+KF G V + P + ++ + D ++F G++Y N Sbjct: 607 NREIQPPFKPKVCGK-GAENFDKFFTRGQPVLTP----PDQLVIANIDQSDFEGFSYVNP 661 Query: 1737 EIVN 1748 + V+ Sbjct: 662 QFVH 665
>O48963:PHOT1_ARATH Phototropin-1 - Arabidopsis thaliana (Mouse-ear cress)| Length = 996 Score = 167 bits (422), Expect = 2e-40 Identities = 114/359 (31%), Positives = 177/359 (49%), Gaps = 10/359 (2%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G++ F+ + +G G G V L + ++AMK + K+ ML R +V +AER +L Sbjct: 658 IGLKHFKPVKPLGSGDTGSVHLVELVGTDQLFAMKAMDKAVMLNRNKVHRARAEREILDL 717 Query: 786 VDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMR--KDTLTEDEAKFYIAETVLAIE 959 +D ++ LY SFQ + LI +Y PGG++ LL R + L ED +FY A+ V+A+E Sbjct: 718 LDHPFLPALYASFQTKTHICLITDYYPGGELFMLLDRQPRKVLKEDAVRFYAAQVVVALE 777 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGL-----CKPLDSSNFPNLNEPDYTPGKGA 1124 +H I+RD+KP+N F L CKP P+++E Sbjct: 778 YLHCQGIIYRDLKPENVLIQGNGDISLSDFDLSCLTSCKP--QLLIPSIDE--------- 826 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 K+ + +Q + + S VGT +YIAPE++ G+ D Sbjct: 827 ------------KKKKKQQKSQQTPIFMAEPMRASNSFVGTEEYIAPEIISGAGHTSAVD 874 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CN 1481 WW+LG +MYEML GY PF + T ++ + LKFP S + K LI +LL + Sbjct: 875 WWALGILMYEMLYGYTPFRGKTRQKTFTNVL--QKDLKFPASIPASLQVKQLIFRLLQRD 932 Query: 1482 VEQRLGT-KGAHEIKAHTWFRGVQWEKLYQMKAAFVPEVN-GELDTQNFEKFEETGAQV 1652 ++RLG +GA+E+K H++F+G+ W A + N EL+T F E G +V Sbjct: 933 PKKRLGCFEGANEVKQHSFFKGINW--------ALIRCTNPPELETPIFSGEAENGEKV 983
>P20444:KPCA_MOUSE Protein kinase C alpha type - Mus musculus (Mouse)| Length = 672 Score = 166 bits (420), Expect = 4e-40 Identities = 119/430 (27%), Positives = 203/430 (47%), Gaps = 7/430 (1%) Frame = +3 Query: 480 KERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFG 659 +E L +K + A++ N ++ E ++ L R K+ DF L ++G+G+FG Sbjct: 295 EEGNMELRQKFEKAKL-GPVGNKVISPSEDRKQPSNNLDRVKL--TDFNFLMVLGKGSFG 351 Query: 660 EVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA-YIVKLYYSFQDDE 836 +V L K + +YA+K LKK +++ VE E+ +LA +D ++ +L+ FQ + Sbjct: 352 KVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVD 411 Query: 837 FLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXX 1016 LY +MEY+ GGD+M + + E +A FY AE + + +HK I+RD+K +N Sbjct: 412 RLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLNNVML 471 Query: 1017 XXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQL 1196 FG+CK + + D + T Sbjct: 472 NSEGHIKIADFGMCK---------------------EHMMDGVTTRT------------- 497 Query: 1197 SHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPM 1376 GTPDYIAPE++ + YG DWW+ G ++YEML G PPF ED Sbjct: 498 -------------FCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDED 544 Query: 1377 STCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQR---LGTKGAHEIKAHTWFRGV 1547 + I+ ++ +P+ LS E + L+ + G +G +++ H +FR + Sbjct: 545 ELFQSIM--EHNVSYPK--SLSKEAVSICKGLMTKQPAKRLGCGPEGERDVREHAFFRRI 600 Query: 1548 QWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKD-ANFVG 1718 WEKL +++ F P+V G+ +NF+KF G V + P + ++ + D ++F G Sbjct: 601 DWEKLENREIQPPFKPKVCGK-GAENFDKFFTRGQPVLTP----PDQLVIANIDQSDFEG 655 Query: 1719 YTYKNFEIVN 1748 ++Y N + V+ Sbjct: 656 FSYVNPQFVH 665
>Q16974:KPC1_APLCA Calcium-dependent protein kinase C - Aplysia californica (California| sea hare) Length = 649 Score = 166 bits (419), Expect = 5e-40 Identities = 112/383 (29%), Positives = 174/383 (45%), Gaps = 7/383 (1%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA 797 DF LT++G+G+FG+V L K + +YA+K LKK +++ VE E+ +LA D Sbjct: 319 DFNFLTVLGKGSFGKVVLAERKGTDELYAIKILKKDVIIQDDDVECTMIEKRVLALPDKP 378 Query: 798 -YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V+L+ FQ + LY +MEY+ GGD+M + ++ E A FY AE + + +H Sbjct: 379 PFLVQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAAFYAAEIAIGLFYLHTQ 438 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 ++RD+K DN FG+CK + D T+R Sbjct: 439 GIVYRDLKLDNVMLDAEGHIKIADFGMCK--------------------ENIMGDKTTR- 477 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 + GTPDYIAPE++L + YG DWW+ G ++YE Sbjct: 478 --------------------------TFCGTPDYIAPEIVLYQPYGRSVDWWAYGVLLYE 511 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQR---LGTK 1505 ML G PPF ED I + ++ +P+ LS E L LL + G Sbjct: 512 MLAGQPPFDGEDEEELFTSITD--HNVSYPK--ALSREAVSLCKGLLTKTPAKRLGCGPN 567 Query: 1506 GAHEIKAHTWFRGVQWEK--LYQMKAAFVPEVNGELDTQNFEK-FEETGAQVQSSSKAGP 1676 G +IK +FR +QWE+ L +++ + P + D NF++ F V + K Sbjct: 568 GERDIKDRAFFRPIQWERIELREVQPPYKPRIKSRKDVSNFDREFTSEAPNVTPTDKL-- 625 Query: 1677 WRKMLPSKDANFVGYTYKNFEIV 1745 ++ F G++Y N E V Sbjct: 626 --FIMNLDQCEFSGFSYVNPEFV 646
>P18653:KS6A1_MOUSE Ribosomal protein S6 kinase alpha-1 - Mus musculus (Mouse)| Length = 724 Score = 164 bits (415), Expect = 1e-39 Identities = 130/424 (30%), Positives = 204/424 (48%), Gaps = 10/424 (2%) Frame = +3 Query: 513 QDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT-- 686 ++A + + ILK + T +++ K FELL ++G+G+FG+V L R+ T Sbjct: 28 EEAGLQPSKDEAILKEISI--THHVKAGSEKADPSQFELLKVLGQGSFGKVFLVRKVTRP 85 Query: 687 -SRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYL 863 S +YAMK LKK+ + R +V K ER++LA+V+ ++VKL+Y+FQ + LYLI+++L Sbjct: 86 DSGHLYAMKVLKKATLKVRDRVR-TKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFL 144 Query: 864 PGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXX 1043 GGD+ T L ++ TE++ KFY+AE L ++ +H I+RD+KP+N Sbjct: 145 RGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLT 204 Query: 1044 XFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRM 1223 FGL K E + H +K Sbjct: 205 DFGLSK------------------------------------------EAIDHEKK---- 218 Query: 1224 LAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNW 1403 AYS GT +Y+APEV+ ++G+ DWWS G +M +D T I+ Sbjct: 219 -AYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLM-----------GKDRKETMTLIL-- 264 Query: 1404 RSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--Q 1568 ++ L P+ LS+E + L+ L N RLG+ GA EIK H ++ + W KLY + Sbjct: 265 KAKLGMPQ--FLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRRE 322 Query: 1569 MKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDAN--FVGYTYKNFEI 1742 +K F P V DT F+ E ++ S P PS A+ F G+++ + Sbjct: 323 IKPPFKPAVAQPDDTFYFD--TEFTSRTPRDSPGIP-----PSAGAHQLFRGFSFVATGL 375 Query: 1743 VNDD 1754 + DD Sbjct: 376 MEDD 379 Score = 98.2 bits (243), Expect = 1e-19 Identities = 86/314 (27%), Positives = 133/314 (42%), Gaps = 4/314 (1%) Frame = +3 Query: 639 IGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYY 818 IG G++ + C K + YA+K + KS +R E ++ LL I+ L Sbjct: 413 IGVGSYSVCKRCVHKATNMEYAVKVIDKS---KRDPSEEIEI---LLRYGQHPNIITLKD 466 Query: 819 SFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIK 998 + D + +YL+ E + GG+++ ++R+ +E EA F + +E +H +HRD+K Sbjct: 467 VYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTISKTVEYLHSQGVVHRDLK 526 Query: 999 PDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKR 1178 P N +S N L D+ AK L L P Sbjct: 527 PSNILYVD---------------ESGNPECLRICDFG---FAKQLRAENGLLMTPCY--- 565 Query: 1179 TQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPF 1358 T +++APEVL ++GY CD WSLG ++Y ML GY PF Sbjct: 566 ----------------------TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPF 603 Query: 1359 Y---SEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTKGAHEIKA 1526 S+ P +I + + L +S KDL+SK+L + QRL K ++ Sbjct: 604 ANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAK---QVLQ 660 Query: 1527 HTWFRGVQWEKLYQ 1568 H W Q +KL Q Sbjct: 661 HPWI--TQKDKLPQ 672
>P05130:KPC1_DROME Protein kinase C, brain isozyme - Drosophila melanogaster (Fruit fly)| Length = 679 Score = 164 bits (415), Expect = 1e-39 Identities = 111/383 (28%), Positives = 175/383 (45%), Gaps = 7/383 (1%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA 797 DF + ++G+G+FG+V L K S +YA+K LKK +++ VE E+ +LA + Sbjct: 349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKP 408 Query: 798 -YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 ++V+L+ FQ + L+ +MEY+ GGD+M + + E A FY AE + +H Sbjct: 409 PFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTK 468 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRL 1154 ++RD+K DN FG+CK Sbjct: 469 GILYRDLKLDNVLLDADGHVKIADFGMCKE------------------------------ 498 Query: 1155 TNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYE 1334 N K T+ + GTPDYIAPE++L + YG DWW+ G ++YE Sbjct: 499 -NIVGDKTTK----------------TFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYE 541 Query: 1335 MLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC---NVEQRLGTK 1505 MLVG PPF ED I + ++ +P+ LS E K+ L N G+ Sbjct: 542 MLVGQPPFDGEDEEELFAAITD--HNVSYPK--SLSKEAKEACKGFLTKQPNKRLGCGSS 597 Query: 1506 GAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEK-FEETGAQVQSSSKAGP 1676 G +++ H +FR + WEK+ +++ F P++ D NF+K F + + K Sbjct: 598 GEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKV-- 655 Query: 1677 WRKMLPSKDANFVGYTYKNFEIV 1745 M+ + FVG++Y N E V Sbjct: 656 --FMMNLDQSEFVGFSYMNPEYV 676
>Q18846:KS6A2_CAEEL Putative ribosomal protein S6 kinase alpha-2 - Caenorhabditis elegans| Length = 772 Score = 164 bits (414), Expect = 2e-39 Identities = 120/399 (30%), Positives = 191/399 (47%), Gaps = 11/399 (2%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCRE---KTSRSVYAMKKLKKSEMLRRGQ-VEHVKAER 770 K+ +E+F LL ++G+GA+G+V L R+ K ++YAMK L+K+ +L + + +EH AER Sbjct: 11 KVSMENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAER 70 Query: 771 NLLAEV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETV 947 +L + + ++V L+Y+FQ D L+++MEY+ GG++ T L + + A+F IAE V Sbjct: 71 QVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEAARFVIAELV 130 Query: 948 LAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAK 1127 +AI+S+H+ I+RD+K +N FGL K Sbjct: 131 VAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLF-------------------- 170 Query: 1128 PLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKK--GYGMEC 1301 LP R A S GT +Y++PEV+ + GY Sbjct: 171 -LPGELDR-------------------------ANSYCGTIEYMSPEVINRPEGGYSDVV 204 Query: 1302 DWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-C 1478 DWWSLG I +E+L G PF + ++ + I K P + + +D I +LL Sbjct: 205 DWWSLGVISFELLTGCSPFTVDGAQNSSKDIAKRIMTKKVPFPKTMDVDARDFIGQLLEK 264 Query: 1479 NVEQRLGTKGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEKFEETGAQV 1652 +E+RLG G EIK H + + W+ + +K VP + +LDTQ F E T Sbjct: 265 KLEKRLGYNGVDEIKNHKFMSSIDWDAAVKRTLKPVIVPRIGHDLDTQFFSA-EFTSQPP 323 Query: 1653 QSSSKAGPWRKMLPSKDANFVGYTYKNFEIV-NDDEVAG 1766 S P + + F GY+Y + ++ +D V G Sbjct: 324 LYSPAESPL-----NANTLFRGYSYVSPSVIFANDNVIG 357 Score = 96.3 bits (238), Expect = 5e-19 Identities = 85/315 (26%), Positives = 148/315 (46%), Gaps = 13/315 (4%) Frame = +3 Query: 636 IIGRGAFGEVRLCREKTSRSVYAMKKLKK---SEMLRRGQV-EHVKAERNLLAEVDSAYI 803 ++G+GAF VR C + +A+K + + S+ R ++ E V+ N I Sbjct: 387 LLGKGAFSVVRRCERVVDGAQFAVKIVSQKFASQAQREARILEMVQGHPN---------I 437 Query: 804 VKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYI 983 V+L+ D YL+ME L G +++ + + + TE EA + + V A++ +H + Sbjct: 438 VQLHDVHSDPLHFYLVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHDKRIV 497 Query: 984 HRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNP 1163 HRD+KP+N L + +DSS L + + A+ LP+ Sbjct: 498 HRDLKPENI--------------LFESIDSSARLRLVDFGF-----ARLLPN-------- 530 Query: 1164 SAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVL----LKKGYGMECDWWSLGAIMY 1331 + ++QL Q R+M T+ Y APEVL + Y +CD WSLG +++ Sbjct: 531 -----SMEQQLKSVQVLRKMTPCFTL---QYAAPEVLDVGDSQPEYNEQCDLWSLGVVLF 582 Query: 1332 EMLVGYPPFYSEDPMSTCRKIVN--WRSHLKFPEEA--KLSSETKDLISKLL-CNVEQRL 1496 ML G PF++ + +I+ R+ F +A +S++ K+LI+ LL + ++RL Sbjct: 583 TMLSGQVPFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADAKNLITGLLTVDPKKRL 642 Query: 1497 GTKGAHEIKAHTWFR 1541 + E+ AH W + Sbjct: 643 SMQ---ELTAHMWLK 654
>P63319:KPCG_RAT Protein kinase C gamma type - Rattus norvegicus (Rat)| Length = 697 Score = 163 bits (412), Expect = 3e-39 Identities = 118/396 (29%), Positives = 184/396 (46%), Gaps = 12/396 (3%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 ++ + DF L ++G+G+FG+V L + S +YA+K LKK +++ V+ E+ +LA Sbjct: 345 RLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLA 404 Query: 783 EVDSA------YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 ++ +L+ +FQ + LY +MEY+ GGD+M + + E A FY AE Sbjct: 405 LGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEI 464 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 + + +H I+RD+K DN FG+CK Sbjct: 465 AIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKE-------------------- 504 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 P +T+R + GTPDYIAPE++ + YG D Sbjct: 505 NVFPGSTTR---------------------------TFCGTPDYIAPEIIAYQPYGKSVD 537 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WWS G ++YEML G PPF ED + I+ + +P+ LS E + L + Sbjct: 538 WWSFGVLLYEMLAGQPPFDGEDEEELFQAIM--EQTVTYPK--SLSREAVAICKGFLTKH 593 Query: 1482 VEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQ 1649 +RLG+ G I+AH +FR + WE+L +++ A F P G +NF+KF A Sbjct: 594 PGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCGR-SGENFDKFFTRAAP 652 Query: 1650 VQSSSKAGPWRKMLPSKD-ANFVGYTYKNFEIVNDD 1754 + P R +L S D A+F G+TY N + V+ D Sbjct: 653 ALTP----PDRLVLASIDQADFQGFTYVNPDFVHPD 684
>P63318:KPCG_MOUSE Protein kinase C gamma type - Mus musculus (Mouse)| Length = 697 Score = 163 bits (412), Expect = 3e-39 Identities = 118/396 (29%), Positives = 184/396 (46%), Gaps = 12/396 (3%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 ++ + DF L ++G+G+FG+V L + S +YA+K LKK +++ V+ E+ +LA Sbjct: 345 RLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLA 404 Query: 783 EVDSA------YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 ++ +L+ +FQ + LY +MEY+ GGD+M + + E A FY AE Sbjct: 405 LGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEI 464 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 + + +H I+RD+K DN FG+CK Sbjct: 465 AIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKE-------------------- 504 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 P +T+R + GTPDYIAPE++ + YG D Sbjct: 505 NVFPGSTTR---------------------------TFCGTPDYIAPEIIAYQPYGKSVD 537 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WWS G ++YEML G PPF ED + I+ + +P+ LS E + L + Sbjct: 538 WWSFGVLLYEMLAGQPPFDGEDEEELFQAIM--EQTVTYPK--SLSREAVAICKGFLTKH 593 Query: 1482 VEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQ 1649 +RLG+ G I+AH +FR + WE+L +++ A F P G +NF+KF A Sbjct: 594 PGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCGR-SGENFDKFFTRAAP 652 Query: 1650 VQSSSKAGPWRKMLPSKD-ANFVGYTYKNFEIVNDD 1754 + P R +L S D A+F G+TY N + V+ D Sbjct: 653 ALTP----PDRLVLASIDQADFQGFTYVNPDFVHPD 684
>P93025:PHOT2_ARATH Phototropin-2 - Arabidopsis thaliana (Mouse-ear cress)| Length = 915 Score = 162 bits (411), Expect = 4e-39 Identities = 104/320 (32%), Positives = 162/320 (50%), Gaps = 4/320 (1%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G+ F+ + +G G G V L K + +YAMK ++K+ ML R + ER +++ Sbjct: 572 VGLHHFKPIKPLGSGDTGSVHLVELKGTGELYAMKAMEKTMMLNRNKAHRACIEREIISL 631 Query: 786 VDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRK--DTLTEDEAKFYIAETVLAIE 959 +D ++ LY SFQ + LI ++ PGG++ LL R+ LTED A+FY AE V+ +E Sbjct: 632 LDHPFLPTLYASFQTSTHVCLITDFCPGGELFALLDRQPMKILTEDSARFYAAEVVIGLE 691 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPD 1139 +H ++RD+KP+N F L ++ P L P Sbjct: 692 YLHCLGIVYRDLKPENILLKKDGHIVLADFDL--SFMTTCTPQLIIP------------- 736 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLG 1319 PS +R++ + L + + S VGT +YIAPE++ G+ DWW+LG Sbjct: 737 -----AAPSKRRRSKSQPLPTFVAEPSTQSNSFVGTEEYIAPEIITGAGHTSAIDWWALG 791 Query: 1320 AIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRL 1496 ++YEML G PF ++ T I++ L FP +S + LI+ LL + RL Sbjct: 792 ILLYEMLYGRTPFRGKNRQKTFANILH--KDLTFPSSIPVSLVGRQLINTLLNRDPSSRL 849 Query: 1497 GTK-GAHEIKAHTWFRGVQW 1553 G+K GA+EIK H +FRG+ W Sbjct: 850 GSKGGANEIKQHAFFRGINW 869
>P10829:KPCG_RABIT Protein kinase C gamma type - Oryctolagus cuniculus (Rabbit)| Length = 697 Score = 162 bits (411), Expect = 4e-39 Identities = 118/396 (29%), Positives = 183/396 (46%), Gaps = 12/396 (3%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 ++ + DF L ++G+G+FG+V L + S +YA+K LKK +++ V+ E+ +LA Sbjct: 345 RLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLA 404 Query: 783 EVDSA------YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 ++ +L+ +FQ + LY +MEY+ GGD+M + + E A FY AE Sbjct: 405 LGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEI 464 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 + + +H I+RD+K DN FG+CK Sbjct: 465 AIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKE-------------------- 504 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 P T+R + GTPDYIAPE++ + YG D Sbjct: 505 NVFPGTTTR---------------------------TFCGTPDYIAPEIIAYQPYGKSVD 537 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WWS G ++YEML G PPF ED + I+ + +P+ LS E + L + Sbjct: 538 WWSFGVLLYEMLAGQPPFDGEDEEELFQAIM--EQTVTYPK--SLSREAVAICKGFLTKH 593 Query: 1482 VEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQ 1649 +RLG+ G I+AH +FR + WE+L +++ A F P G +NF+KF A Sbjct: 594 PGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCGR-SGENFDKFFTRAAP 652 Query: 1650 VQSSSKAGPWRKMLPSKD-ANFVGYTYKNFEIVNDD 1754 + P R +L S D A+F G+TY N + V+ D Sbjct: 653 AVTP----PDRLVLASIDQADFQGFTYVNPDFVHPD 684
>P05128:KPCG_BOVIN Protein kinase C gamma type - Bos taurus (Bovine)| Length = 682 Score = 162 bits (409), Expect = 7e-39 Identities = 117/396 (29%), Positives = 183/396 (46%), Gaps = 12/396 (3%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 ++ + DF L ++G+G+FG+V L + S +YA+K LKK +++ V+ E+ +LA Sbjct: 330 RLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLA 389 Query: 783 EVDSA------YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 ++ +L+ +FQ + LY +MEY+ GGD+M + + E A FY AE Sbjct: 390 LGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEI 449 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 + + +H I+RD+K DN FG+CK Sbjct: 450 AIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKE-------------------- 489 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 P +T+R + GTPDYIAPE++ + YG D Sbjct: 490 NVFPGSTTR---------------------------TFCGTPDYIAPEIIAYQPYGKSVD 522 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WWS G ++YEML G PPF ED + I+ + +P+ LS E + L + Sbjct: 523 WWSFGVLLYEMLAGQPPFDGEDEEELFQAIM--EQTVTYPK--SLSREAVAICKGFLTKH 578 Query: 1482 VEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEETGAQ 1649 +RLG+ G I+AH +FR + W++L +++ A F P G +NF+KF A Sbjct: 579 PAKRLGSGPDGEPTIRAHGFFRWIDWDRLERLEIAPPFRPRPCGR-SGENFDKFFTRAAP 637 Query: 1650 VQSSSKAGPWRKMLPSKD-ANFVGYTYKNFEIVNDD 1754 + P R +L S D A F G+TY N + V+ D Sbjct: 638 ALTP----PDRLVLASIDQAEFQGFTYVNPDFVHPD 669
>Q16975:KPC2_APLCA Calcium-independent protein kinase C - Aplysia californica| (California sea hare) Length = 743 Score = 161 bits (408), Expect = 9e-39 Identities = 106/356 (29%), Positives = 166/356 (46%), Gaps = 9/356 (2%) Frame = +3 Query: 588 RLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAE 767 R ++ + DF + ++G+G+FG+V L +K + VYA+K LKK +++ VE E Sbjct: 392 RSHHSRISLHDFNFIKVLGKGSFGKVMLAEKKGTDEVYAIKVLKKDVIIQDDDVECTMTE 451 Query: 768 RNLLA-EVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 + +LA ++ L+ SFQ E L+ +MEY+ GGD+M + R E A+FY AE Sbjct: 452 KRILALSAKHPFLTALHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEPRARFYAAEV 511 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 LA+ +H+H I+RD+K DN FG+CK + N Sbjct: 512 TLALMFLHRHGIIYRDLKLDNILLDAEGHCKIADFGMCKEGMTEN--------------- 556 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 L + GTPDYIAPE+L + Y D Sbjct: 557 --------------------------------KLTQTFCGTPDYIAPEILQELKYDASVD 584 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WW+LG +MYEM+ G PPF +++ I++ + +P LS E ++ + N Sbjct: 585 WWALGVLMYEMMAGQPPFEADNEDDLFESILH--DDVLYP--VWLSKEAVSILKGFMTKN 640 Query: 1482 VEQRLG---TKGAHE-IKAHTWF-RGVQWEKLYQ--MKAAFVPEVNGELDTQNFEK 1628 +RLG T+G + I H +F + WE L Q +K F P++ + D NF++ Sbjct: 641 PAKRLGCVTTQGCEKAILVHPFFHEKIDWEALEQRKVKPPFKPKIKNKTDANNFDR 696
>Q4R4U2:KPCG_MACFA Protein kinase C gamma type - Macaca fascicularis (Crab eating| macaque) (Cynomolgus monkey) Length = 697 Score = 160 bits (406), Expect = 1e-38 Identities = 117/396 (29%), Positives = 182/396 (45%), Gaps = 12/396 (3%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 ++ + DF L ++G+G+FG+V L + S +YA+K LKK +++ V+ E+ +LA Sbjct: 345 RLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLA 404 Query: 783 EVDSA------YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 ++ +L+ +FQ + LY +MEY+ GGD+M + + E A FY AE Sbjct: 405 LGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEI 464 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 + + +H I+RD+K DN FG+CK Sbjct: 465 AIGLFFLHNQGIIYRDLKLDNVVLDAEGLIKITDFGMCK--------------------E 504 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 P T+R + GTPDYIAPE++ + YG D Sbjct: 505 NVFPGTTTR---------------------------TFCGTPDYIAPEIIAYQPYGKSVD 537 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WWS G ++YEML G PPF ED + I+ + +P+ LS E + L + Sbjct: 538 WWSFGVLLYEMLAGQPPFDGEDEEELFQAIM--EQTVTYPK--SLSREAVAICKGFLTKH 593 Query: 1482 VEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKFEETGAQ 1649 +RLG+ G I+AH +FR + WE+L +++ F P G +NF+KF A Sbjct: 594 PGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGR-SGENFDKFFTRAAP 652 Query: 1650 VQSSSKAGPWRKMLPSKD-ANFVGYTYKNFEIVNDD 1754 + P R +L S D A+F G+TY N + V+ D Sbjct: 653 ALTP----PDRLVLASIDQADFQGFTYVNPDFVHPD 684
>P05129:KPCG_HUMAN Protein kinase C gamma type - Homo sapiens (Human)| Length = 697 Score = 160 bits (406), Expect = 1e-38 Identities = 117/396 (29%), Positives = 182/396 (45%), Gaps = 12/396 (3%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 ++ + DF L ++G+G+FG+V L + S +YA+K LKK +++ V+ E+ +LA Sbjct: 345 RLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLA 404 Query: 783 EVDSA------YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAET 944 ++ +L+ +FQ + LY +MEY+ GGD+M + + E A FY AE Sbjct: 405 LGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEI 464 Query: 945 VLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGA 1124 + + +H I+RD+K DN FG+CK Sbjct: 465 AIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCK--------------------E 504 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 P T+R + GTPDYIAPE++ + YG D Sbjct: 505 NVFPGTTTR---------------------------TFCGTPDYIAPEIIAYQPYGKSVD 537 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WWS G ++YEML G PPF ED + I+ + +P+ LS E + L + Sbjct: 538 WWSFGVLLYEMLAGQPPFDGEDEEELFQAIM--EQTVTYPK--SLSREAVAICKGFLTKH 593 Query: 1482 VEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMK--AAFVPEVNGELDTQNFEKFEETGAQ 1649 +RLG+ G I+AH +FR + WE+L +++ F P G +NF+KF A Sbjct: 594 PGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGR-SGENFDKFFTRAAP 652 Query: 1650 VQSSSKAGPWRKMLPSKD-ANFVGYTYKNFEIVNDD 1754 + P R +L S D A+F G+TY N + V+ D Sbjct: 653 ALTP----PDRLVLASIDQADFQGFTYVNPDFVHPD 684
>Q04759:KPCT_HUMAN Protein kinase C theta type - Homo sapiens (Human)| Length = 706 Score = 160 bits (405), Expect = 2e-38 Identities = 120/416 (28%), Positives = 188/416 (45%), Gaps = 7/416 (1%) Frame = +3 Query: 522 EVPAEEQNNILKHLEKKETEYMRLQRH-KMGVEDFELLTIIGRGAFGEVRLCREKTSRSV 698 E P +E + + HL + E R K+ +EDF L ++G+G+FG+V L K + Sbjct: 347 ESPLDEVDKMC-HLPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQF 405 Query: 699 YAMKKLKKSEMLRRGQVEHVKAERNLLAEV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGD 875 +A+K LKK +L VE E+ +L+ + ++ ++ +FQ E L+ +MEYL GGD Sbjct: 406 FAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGD 465 Query: 876 MMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGL 1055 +M + A FY AE +L ++ +H ++RD+K DN FG+ Sbjct: 466 LMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGM 525 Query: 1056 CKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYS 1235 CK + L + N + Sbjct: 526 CK-----------------------------------------ENMLGDAKTN------T 538 Query: 1236 TVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHL 1415 GTPDYIAPE+LL + Y DWWS G ++YEML+G PF+ +D I + Sbjct: 539 FCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSI-----RM 593 Query: 1416 KFPEEAK-LSSETKDLISKLLC-NVEQRLGTKGAHEIKAHTWFRGVQWEKL--YQMKAAF 1583 P + L E KDL+ KL E+RLG +G +I+ H FR + WE+L ++ F Sbjct: 594 DNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRG--DIRQHPLFREINWEELERKEIDPPF 651 Query: 1584 VPEVNGELDTQNFEK-FEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVN 1748 P+V D NF+K F ++ + +A ++ S D N ++NF +N Sbjct: 652 RPKVKSPFDCSNFDKEFLNEKPRLSFADRA-----LINSMDQNM----FRNFSFMN 698
>P38070:KBN8_YEAST Probable serine/threonine-protein kinase YBR028C - Saccharomyces| cerevisiae (Baker's yeast) Length = 525 Score = 160 bits (404), Expect = 3e-38 Identities = 99/314 (31%), Positives = 154/314 (49%), Gaps = 26/314 (8%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEML------------------- 734 + DF+ + ++G+GA+G+V L ++ + +YAMK+L+K+E+L Sbjct: 125 LHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGN 184 Query: 735 -------RRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLM 893 ++E AER++L+E++ IVKL+YSF D+ LYL+++Y+PGG++ L Sbjct: 185 NNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLK 244 Query: 894 RKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDS 1073 TL E FY AE A+ +H ++RD+KP+N FGL K S Sbjct: 245 EHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSK--KS 302 Query: 1074 SNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPD 1253 +N ++E D P+N + L YS +GTP+ Sbjct: 303 ANDSAVDEED----------PENVNAL-------------------------YSIIGTPE 327 Query: 1254 YIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEA 1433 Y APE+LL K Y CDW+SLG ++Y+MLVG PP+ + KI + K P Sbjct: 328 YCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIP--F 385 Query: 1434 KLSSETKDLISKLL 1475 LS KD+++ LL Sbjct: 386 YLSEGMKDILNALL 399
>Q9XTG7:AKT2_CAEEL Serine/threonine-protein kinase akt-2 - Caenorhabditis elegans| Length = 528 Score = 159 bits (402), Expect = 4e-38 Identities = 106/359 (29%), Positives = 167/359 (46%), Gaps = 5/359 (1%) Frame = +3 Query: 594 QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN 773 +++ + ++DF+ L ++G+G FG+V LCREK+S +YA+K ++K ++ R +V H E Sbjct: 171 RKNTVTMDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENR 230 Query: 774 LLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLA 953 +L ++ L YSFQ + +ME+ GG++ T L R T +E +FY +E +LA Sbjct: 231 VLYACVHPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILA 290 Query: 954 IESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 + +H N ++RD+K +N FGLCK Sbjct: 291 LGYLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCK------------------------ 326 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 E++ + K + GTP+Y+APEV+ Y DWW Sbjct: 327 ------------------EEIKYGDKTS-----TFCGTPEYLAPEVIEDIDYDRSVDWWG 363 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQR 1493 +G +MYEM+ G PF +++ I LKFP +LS E L+S LL V + Sbjct: 364 VGVVMYEMMCGRLPFSAKENGKLFELITT--CDLKFPN--RLSPEAVTLLSGLLERVPAK 419 Query: 1494 ---LGTKGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEKFEETGAQVQ 1655 G A E+ +F+ V WE +++ F P V E DT F++ E T VQ Sbjct: 420 RLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDTSFFDR-EFTSMPVQ 477
>O55173:PDPK1_RAT 3-phosphoinositide-dependent protein kinase 1 - Rattus norvegicus| (Rat) Length = 559 Score = 159 bits (401), Expect = 6e-38 Identities = 127/446 (28%), Positives = 202/446 (45%), Gaps = 13/446 (2%) Frame = +3 Query: 594 QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN 773 Q K EDF+ I+G G+F V L RE + YA+K L+K +++ +V +V ER+ Sbjct: 76 QPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERD 135 Query: 774 LLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLA 953 +++ +D + VKLY++FQDDE LY + Y G+++ + + + E +FY AE V A Sbjct: 136 VMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSA 195 Query: 954 IESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 +E +H IHRD+KP+N FG K L PD Sbjct: 196 LEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL---------SPD---------- 236 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 +++ A S VGT Y++PE+L +K D W+ Sbjct: 237 --------------------------SKQARANSFVGTAQYVSPELLTEKSACKSSDLWA 270 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG I+Y+++ G PPF + + +KI+ + FPE K + +DL+ KLL + + Sbjct: 271 LGCIIYQLVAGLPPFRAGNEYLIFQKII--KLEYDFPE--KFFPKARDLVEKLLVLDATK 326 Query: 1491 RLG---TKGAHEIKAHTWFRGVQWEKLYQMK----AAFVPEVNGELDTQNFEKFEETGA- 1646 RLG +G +KAH +F + WE L+Q A++P ++ E D + ++ + Sbjct: 327 RLGCEEMEGYGPLKAHPFFESITWENLHQQTPPKLTAYLPAMS-EDDEDCYGNYDNLLSQ 385 Query: 1647 ----QVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAELKKKSSKSKRPTI 1814 QV SSS + L + DA+ + N E D EL + S+ ++ Sbjct: 386 FGCMQVSSSSSS----HSLCAVDASLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEK--- 438 Query: 1815 KTLFESMDEDEPVHGSFLNMLPHKEG 1892 + L E P H N L K G Sbjct: 439 RLLLEKQAGGNPWHQFVENNLILKMG 464
>Q9WTQ0:KPCT_RAT Protein kinase C theta type - Rattus norvegicus (Rat)| Length = 707 Score = 159 bits (401), Expect = 6e-38 Identities = 114/387 (29%), Positives = 177/387 (45%), Gaps = 5/387 (1%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 K+ ++DF L ++G+G+FG+V L K ++ +A+K LKK +L VE E+ +L+ Sbjct: 374 KLKIDDFILHKMLGKGSFGKVFLAEFKRTKQFFAIKALKKDVVLMDDDVECTMVEKRVLS 433 Query: 783 EV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 + ++ ++ +FQ E L+ +MEYL GGD+M + A FY AE +L ++ Sbjct: 434 LAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEVILGLQ 493 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPD 1139 +H ++RD+K DN FG+CK Sbjct: 494 FLHSKGIVYRDLKLDNILLDRDGHIKIADFGMCK-------------------------- 527 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLG 1319 + L + N + GTPDYIAPE+LL + Y DWWS G Sbjct: 528 ---------------ENMLGDAKTN------TFCGTPDYIAPEILLGQKYNHSVDWWSFG 566 Query: 1320 AIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAK-LSSETKDLISKLLC-NVEQR 1493 ++YEML+G PF+ +D I + P + L E KDL+ KL E+R Sbjct: 567 VLLYEMLIGQSPFHGQDEEELFHSI-----RMDNPFYPRWLEREAKDLLVKLFVREPEKR 621 Query: 1494 LGTKGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSK 1667 LG +G +I+ H FR + WE+L ++ F P+V D NF+K E ++ S Sbjct: 622 LGVRG--DIRQHPLFREINWEELERKEIDPPFRPKVKSPYDCSNFDK--EFLSEKPRLSF 677 Query: 1668 AGPWRKMLPSKDANFVGYTYKNFEIVN 1748 A R ++ S D N + NF +N Sbjct: 678 AD--RALINSMDQNM----FSNFSFIN 698
>Q9Z2A0:PDPK1_MOUSE 3-phosphoinositide-dependent protein kinase 1 - Mus musculus (Mouse)| Length = 559 Score = 158 bits (400), Expect = 7e-38 Identities = 100/329 (30%), Positives = 158/329 (48%), Gaps = 4/329 (1%) Frame = +3 Query: 594 QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN 773 Q K EDF+ I+G G+F V L RE + YA+K L+K +++ +V +V ER+ Sbjct: 76 QPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERD 135 Query: 774 LLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLA 953 +++ +D + VKLY++FQDDE LY + Y G+++ + + + E +FY AE V A Sbjct: 136 VMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSA 195 Query: 954 IESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 +E +H IHRD+KP+N FG K L Sbjct: 196 LEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLS--------------------- 234 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 ++++ A S VGT Y++PE+L +K D W+ Sbjct: 235 ------------------------PESKQARANSFVGTAQYVSPELLTEKSACKSSDLWA 270 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG I+Y+++ G PPF + + +KI+ H FPE K + +DL+ KLL + + Sbjct: 271 LGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYH--FPE--KFFPKARDLVEKLLVLDATK 326 Query: 1491 RLG---TKGAHEIKAHTWFRGVQWEKLYQ 1568 RLG +G +KAH +F + WE L+Q Sbjct: 327 RLGCEEMEGYGPLKAHPFFETITWENLHQ 355
>O15530:PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 - Homo sapiens (Human)| Length = 556 Score = 158 bits (400), Expect = 7e-38 Identities = 125/446 (28%), Positives = 200/446 (44%), Gaps = 13/446 (2%) Frame = +3 Query: 594 QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN 773 Q K EDF+ I+G G+F V L RE + YA+K L+K +++ +V +V ER+ Sbjct: 73 QPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERD 132 Query: 774 LLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLA 953 +++ +D + VKLY++FQDDE LY + Y G+++ + + + E +FY AE V A Sbjct: 133 VMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSA 192 Query: 954 IESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPL 1133 +E +H IHRD+KP+N FG K L Sbjct: 193 LEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLS--------------------- 231 Query: 1134 PDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWS 1313 ++++ A S VGT Y++PE+L +K D W+ Sbjct: 232 ------------------------PESKQARANSFVGTAQYVSPELLTEKSACKSSDLWA 267 Query: 1314 LGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQ 1490 LG I+Y+++ G PPF + + +KI+ + FPE K + +DL+ KLL + + Sbjct: 268 LGCIIYQLVAGLPPFRAGNEYLIFQKII--KLEYDFPE--KFFPKARDLVEKLLVLDATK 323 Query: 1491 RLG---TKGAHEIKAHTWFRGVQWEKLYQMK----AAFVPEVNGELDTQNFEKFEETGA- 1646 RLG +G +KAH +F V WE L+Q A++P ++ E D + ++ + Sbjct: 324 RLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMS-EDDEDCYGNYDNLLSQ 382 Query: 1647 ----QVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAELKKKSSKSKRPTI 1814 QV SSS + L + D + N E D + EL + S+ ++ Sbjct: 383 FGCMQVSSSSSS----HSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEK--- 435 Query: 1815 KTLFESMDEDEPVHGSFLNMLPHKEG 1892 + L E P H N L K G Sbjct: 436 RLLLEKQAGGNPWHQFVENNLILKMG 461
>Q5R4K9:KPCI_PONPY Protein kinase C iota type - Pongo pygmaeus (Orangutan)| Length = 587 Score = 158 bits (399), Expect = 1e-37 Identities = 112/399 (28%), Positives = 191/399 (47%), Gaps = 15/399 (3%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G++DF+LL +IGRG++ +V L R K + +YAMK +KK + ++ V+ E+++ + Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQ 299 Query: 786 VDS-AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 + ++V L+ FQ + L+ ++EY+ GGD+M + R+ L E+ A+FY AE LA+ Sbjct: 300 ASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNY 359 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H+ I+RD+K DN +G+CK +G +P D Sbjct: 360 LHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCK------------------EGLRP-GDT 400 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 TS + GTP+YIAPE+L + YG DWW+LG Sbjct: 401 TS----------------------------TFCGTPNYIAPEILRGEDYGFSVDWWALGV 432 Query: 1323 IMYEMLVGYPPF----YSEDPMSTCRKI---VNWRSHLKFPE--EAKLSSETKDLISKLL 1475 +M+EM+ G PF S++P V ++ P K +S K ++K Sbjct: 433 LMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNK-- 490 Query: 1476 CNVEQRLG---TKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEET 1640 + ++RLG G +I+ H +FR V W+ + Q + F P ++GE NF+ + T Sbjct: 491 -DPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDS-QFT 548 Query: 1641 GAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDE 1757 VQ + + + + F G+ Y N +++ +E Sbjct: 549 NEPVQLTPDDDDIVRKIDQSE--FEGFEYINPLLMSAEE 585
>Q62074:KPCI_MOUSE Protein kinase C iota type - Mus musculus (Mouse)| Length = 586 Score = 158 bits (399), Expect = 1e-37 Identities = 112/399 (28%), Positives = 191/399 (47%), Gaps = 15/399 (3%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G++DF+LL +IGRG++ +V L R K + +YAMK +KK + ++ V+ E+++ + Sbjct: 239 LGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQ 298 Query: 786 VDS-AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 + ++V L+ FQ + L+ ++EY+ GGD+M + R+ L E+ A+FY AE LA+ Sbjct: 299 ASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNY 358 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H+ I+RD+K DN +G+CK +G +P D Sbjct: 359 LHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCK------------------EGLRP-GDT 399 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 TS + GTP+YIAPE+L + YG DWW+LG Sbjct: 400 TS----------------------------TFCGTPNYIAPEILRGEDYGFSVDWWALGV 431 Query: 1323 IMYEMLVGYPPF----YSEDPMSTCRKI---VNWRSHLKFPE--EAKLSSETKDLISKLL 1475 +M+EM+ G PF S++P V ++ P K +S K ++K Sbjct: 432 LMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNK-- 489 Query: 1476 CNVEQRLG---TKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEET 1640 + ++RLG G +I+ H +FR V W+ + Q + F P ++GE NF+ + T Sbjct: 490 -DPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDS-QFT 547 Query: 1641 GAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDE 1757 VQ + + + + F G+ Y N +++ +E Sbjct: 548 NEPVQLTPDDDDIVRKIDQSE--FEGFEYINPLLMSAEE 584
>P41743:KPCI_HUMAN Protein kinase C iota type - Homo sapiens (Human)| Length = 587 Score = 158 bits (399), Expect = 1e-37 Identities = 112/399 (28%), Positives = 191/399 (47%), Gaps = 15/399 (3%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G++DF+LL +IGRG++ +V L R K + +YAMK +KK + ++ V+ E+++ + Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQ 299 Query: 786 VDS-AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 + ++V L+ FQ + L+ ++EY+ GGD+M + R+ L E+ A+FY AE LA+ Sbjct: 300 ASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNY 359 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H+ I+RD+K DN +G+CK +G +P D Sbjct: 360 LHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCK------------------EGLRP-GDT 400 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 TS + GTP+YIAPE+L + YG DWW+LG Sbjct: 401 TS----------------------------TFCGTPNYIAPEILRGEDYGFSVDWWALGV 432 Query: 1323 IMYEMLVGYPPF----YSEDPMSTCRKI---VNWRSHLKFPE--EAKLSSETKDLISKLL 1475 +M+EM+ G PF S++P V ++ P K +S K ++K Sbjct: 433 LMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNK-- 490 Query: 1476 CNVEQRLG---TKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEET 1640 + ++RLG G +I+ H +FR V W+ + Q + F P ++GE NF+ + T Sbjct: 491 -DPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDS-QFT 548 Query: 1641 GAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDE 1757 VQ + + + + F G+ Y N +++ +E Sbjct: 549 NEPVQLTPDDDDIVRKIDQSE--FEGFEYINPLLMSAEE 585
>Q02111:KPCT_MOUSE Protein kinase C theta type - Mus musculus (Mouse)| Length = 707 Score = 157 bits (398), Expect = 1e-37 Identities = 114/387 (29%), Positives = 176/387 (45%), Gaps = 5/387 (1%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 K+ ++DF L ++G+G+FG+V L K + +A+K LKK +L VE E+ +L+ Sbjct: 374 KLKIDDFILHKMLGKGSFGKVFLAEFKRTNQFFAIKALKKDVVLMDDDVECTMVEKRVLS 433 Query: 783 EV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 + ++ ++ +FQ E L+ +MEYL GGD+M + A FY AE +L ++ Sbjct: 434 LAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEVILGLQ 493 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPD 1139 +H ++RD+K DN FG+CK Sbjct: 494 FLHSKGIVYRDLKLDNILLDRDGHIKIADFGMCK-------------------------- 527 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLG 1319 + L + N + GTPDYIAPE+LL + Y DWWS G Sbjct: 528 ---------------ENMLGDAKTN------TFCGTPDYIAPEILLGQKYNHSVDWWSFG 566 Query: 1320 AIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAK-LSSETKDLISKLLC-NVEQR 1493 ++YEML+G PF+ +D I + P + L E KDL+ KL E+R Sbjct: 567 VLVYEMLIGQSPFHGQDEEELFHSI-----RMDNPFYPRWLEREAKDLLVKLFVREPEKR 621 Query: 1494 LGTKGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSK 1667 LG +G +I+ H FR + WE+L ++ F P+V D NF+K E ++ S Sbjct: 622 LGVRG--DIRQHPLFREINWEELERKEIDPPFRPKVKSPYDCSNFDK--EFLSEKPRLSF 677 Query: 1668 AGPWRKMLPSKDANFVGYTYKNFEIVN 1748 A R ++ S D N + NF +N Sbjct: 678 AD--RALINSMDQNM----FSNFSFIN 698
>Q05513:KPCZ_HUMAN Protein kinase C zeta type - Homo sapiens (Human)| Length = 592 Score = 157 bits (397), Expect = 2e-37 Identities = 125/449 (27%), Positives = 217/449 (48%), Gaps = 29/449 (6%) Frame = +3 Query: 498 LERKLQDAEVPAEEQNNIL------KHLE-KKETEYMRLQRHKM---------GVEDFEL 629 ++ K +DA++P+EE + I KH K ++E ++ M G++DF+L Sbjct: 195 VDDKNEDADLPSEETDGIAYISSSRKHDSIKDDSEDLKPVIDGMDGIKISQGLGLQDFDL 254 Query: 630 LTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS-AYIV 806 + +IGRG++ +V L R K + +YAMK +KK + ++ V+ E+++ + S ++V Sbjct: 255 IRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNPFLV 314 Query: 807 KLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIH 986 L+ FQ L+L++EY+ GGD+M + R+ L E+ A+FY AE +A+ +H+ I+ Sbjct: 315 GLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIY 374 Query: 987 RDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPS 1166 RD+K DN +G+CK +G P D TS Sbjct: 375 RDLKLDNVLLDADGHIKLTDYGMCK------------------EGLGP-GDTTS------ 409 Query: 1167 APKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVG 1346 + GTP+YIAPE+L + YG DWW+LG +M+EM+ G Sbjct: 410 ----------------------TFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAG 447 Query: 1347 YPPF--YSEDP-MSTCRKI--VNWRSHLKFPE--EAKLSSETKDLISKLLCNVEQRLGTK 1505 PF +++P M+T + V ++ P K S K ++K + ++RLG + Sbjct: 448 RSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNK---DPKERLGCR 504 Query: 1506 ---GAHEIKAHTWFRGVQWEKLYQMKA--AFVPEVNGELDTQNFEKFEETGAQVQSSSKA 1670 G +IK+H +FR + W+ L + +A F P++ + NF+ + T VQ + Sbjct: 505 PQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNFDT-QFTSEPVQLTPDD 563 Query: 1671 GPWRKMLPSKDANFVGYTYKNFEIVNDDE 1757 K + + F G+ Y N +++ +E Sbjct: 564 EDAIKRIDQSE--FEGFEYINPLLLSTEE 590
>Q90XF2:KPCI_DANRE Protein kinase C iota type - Danio rerio (Zebrafish) (Brachydanio| rerio) Length = 588 Score = 157 bits (396), Expect = 2e-37 Identities = 113/399 (28%), Positives = 189/399 (47%), Gaps = 15/399 (3%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G+ DF+LL +IGRG++ +V L R K + +YAMK +KK + ++ V+ E+++ + Sbjct: 241 LGLIDFDLLRVIGRGSYAKVLLVRLKKTERIYAMKVVKKELVNDDEDIDWVQTEKHVFEQ 300 Query: 786 VDS-AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 + ++V L+ FQ + L+ ++EY+ GGD+M + R+ L E+ A+FY AE LA+ Sbjct: 301 ASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNY 360 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H+ I+RD+K DN +G+CK +G +P D Sbjct: 361 LHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCK------------------EGLRP-GDT 401 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 TS + GTP+YIAPE+L + YG DWW+LG Sbjct: 402 TS----------------------------TFCGTPNYIAPEILRGEDYGFSVDWWALGV 433 Query: 1323 IMYEMLVGYPPF----YSEDPMSTCRKI---VNWRSHLKFPE--EAKLSSETKDLISKLL 1475 +M+EM+ G PF S++P V ++ P K +S K ++K Sbjct: 434 LMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKGFLNK-- 491 Query: 1476 CNVEQRLG---TKGAHEIKAHTWFRGVQWEKLYQMKAA--FVPEVNGELDTQNFEKFEET 1640 ++RLG G +I AH +FR V W+ + Q + F P ++GE NF+ + T Sbjct: 492 -ESKERLGCHPQTGFADIMAHPFFRNVDWDLMEQKQVVPPFKPNISGEFGLDNFDA-QFT 549 Query: 1641 GAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDE 1757 +Q + K + + F G+ Y N +++ +E Sbjct: 550 NEPIQLTPDDDDAVKKIDQSE--FEGFEYINPLLMSAEE 586
>P47997:G11A_ORYSA Protein kinase G11A - Oryza sativa (Rice)| Length = 589 Score = 156 bits (395), Expect = 3e-37 Identities = 113/367 (30%), Positives = 173/367 (47%), Gaps = 37/367 (10%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G+ F+LL +G G G V L ++S +AMK + K+ + R ++ + E+ +L Sbjct: 190 LGLSHFKLLKKLGCGDIGSVYLSELSGTKSYFAMKVMDKASLASRKKLLRAQTEKEILQC 249 Query: 786 VDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRK--DTLTEDEAKFYIAETVLAIE 959 +D ++ LY F+ D+F L+ME+ PGGD+ TL R+ E KFY+AE +LA+E Sbjct: 250 LDHPFLPTLYTHFETDKFSCLVMEFCPGGDLHTLRQRQRGKYFPEQAVKFYVAEILLAME 309 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGL-CKPLDSSNFPNLNEPD------YTPGK 1118 +H I+RD+KP+N F L + S + PD Sbjct: 310 YLHMLGIIYRDLKPENVLVREDGHIMLSDFDLSLRCAVSPTLIRSSNPDAEALRKNNQAY 369 Query: 1119 GAKPLPDNTSRLTNPSA--------------------PKRTQQEQLSHWQK------NRR 1220 +P S + PS PK Q+S W + + R Sbjct: 370 CVQPACVEPSCMIQPSCATPTTCFGPRFFSKSKKDRKPKPEVVNQVSPWPELIAEPSDAR 429 Query: 1221 MLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVN 1400 +++ VGT +Y+APE++ +G+G DWW+ G +YE+L G PF +T ++ Sbjct: 430 SMSF--VGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGNRATLFNVIG 487 Query: 1401 WRSHLKFPEEAKLSSETKDLISKLLC-NVEQRLGTK-GAHEIKAHTWFRGVQWEKLYQMK 1574 L+FPE +S +DLI LL +QRLG K GA EIK H +F GV W + + Sbjct: 488 --QPLRFPEYPVVSFSARDLIRGLLVKEPQQRLGCKRGATEIKQHPFFEGVNWALI---R 542 Query: 1575 AAFVPEV 1595 A PEV Sbjct: 543 CASPPEV 549
>P36583:PCK2_SCHPO Protein kinase C-like 2 - Schizosaccharomyces pombe (Fission yeast)| Length = 1016 Score = 156 bits (394), Expect = 4e-37 Identities = 116/483 (24%), Positives = 215/483 (44%), Gaps = 27/483 (5%) Frame = +3 Query: 261 HCEHTMDSARSWFQKFQPRDKSKSPAVPASHGKDPGKPPVDDAPSSATKQKVAAAKQYIE 440 H H ++S K + DK+ +V + P P D P+S + K+ Sbjct: 555 HKHHHHKKSKSSSSKHKENDKA---SVSITTTTTPSITPADPVPTSPKPLAIEPVKRKPV 611 Query: 441 NHYKTQMKSLQDRK--ERRWMLERKLQDAE-----------------VPAEEQNNILKHL 563 + ++ S+ D K ++E+K+ D VP+ E + + + L Sbjct: 612 HAGNLEVTSVSDNKLGATVQVVEQKVDDKADALTKPPSLDAVKEPIPVPSVETSVVAQDL 671 Query: 564 EKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRG 743 K ++G+EDF L+++G+G FG+V L K+ + +YA+K LKK +L Sbjct: 672 THKAK--------RIGLEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILEND 723 Query: 744 QVEHVKAERNLLAEVD---SAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTE 914 +VE K+E+ + + ++V L+ FQ + +Y +M+++ GGD+M L ++++ + Sbjct: 724 EVESTKSEKRVFLVANRERHPFLVNLHSCFQTETRIYFVMDFVSGGDLM-LHIQQEQFSR 782 Query: 915 DEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLN 1094 A+FY AE LA++ H + I+RD+K DN +GLCK Sbjct: 783 RRAQFYAAEVCLALKYFHDNGIIYRDLKLDNILLSPDGHVKVADYGLCKE---------- 832 Query: 1095 EPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVL 1274 W N + GTP+++APE+L Sbjct: 833 ----------------------------------DMWHDN---TTATFCGTPEFMAPEIL 855 Query: 1275 LKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETK 1454 L++ Y DWW+ G ++Y+ML+G PF ED I++ +P + ++ Sbjct: 856 LEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILS--DEPLYP--IHMPRDSV 911 Query: 1455 DLISKLLC-NVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQMKA--AFVPEVNGELDTQN 1619 ++ +LL + ++RLG+ A ++ H +F + W+ +Y + ++P +N DT+ Sbjct: 912 SILQQLLTRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIPSLNSPTDTKY 971 Query: 1620 FEK 1628 F++ Sbjct: 972 FDE 974
>P36582:PCK1_SCHPO Protein kinase C-like 1 - Schizosaccharomyces pombe (Fission yeast)| Length = 988 Score = 156 bits (394), Expect = 4e-37 Identities = 98/354 (27%), Positives = 172/354 (48%), Gaps = 7/354 (1%) Frame = +3 Query: 588 RLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAE 767 R +++++ ++DF L ++G+G FG+V L K ++ YA+K LKK +L+ ++E +K E Sbjct: 653 REKKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTE 712 Query: 768 RNLLAEVDS---AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIA 938 +++ + +++ L+ SFQ +Y +MEY+ GGD+M + R+ + A+FY A Sbjct: 713 KHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQQ-FSVKRARFYGA 771 Query: 939 ETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGK 1118 E LA++ H++ +RD+K DN +GLCK Sbjct: 772 EVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCK------------------- 812 Query: 1119 GAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGME 1298 L NT+ + GTP+++APE+LL++ Y + Sbjct: 813 -ENMLLGNTTS---------------------------TFCGTPEFMAPEILLEQQYSKD 844 Query: 1299 CDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC 1478 DWW+ G +MY+ML+G PF ED I++ A S + L+++ Sbjct: 845 VDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPINMPADAVSLLRGLLTR--- 901 Query: 1479 NVEQRLGT--KGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEK 1628 + QRLG+ K A+E+ AH +F + W+ LY + ++ P +N D NF++ Sbjct: 902 DPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPSYKPLINDPRDLNNFDE 955
>Q25378:KPC1_LYTPI Protein kinase C - Lytechinus pictus (Painted sea urchin)| Length = 658 Score = 156 bits (394), Expect = 4e-37 Identities = 110/381 (28%), Positives = 177/381 (46%), Gaps = 15/381 (3%) Frame = +3 Query: 534 EEQNNILKHLEKKETEYMRLQRHK----MGV---EDFELLTIIGRGAFGEVRLCREKTSR 692 +E + +K L E+++ Q MGV DF L+++G+G+FG+V L +K + Sbjct: 289 DELTSNIKKLPMPTQEHVKPQNSNSMSGMGVVRASDFNFLSVLGKGSFGKVMLAEKKGTD 348 Query: 693 SVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS-AYIVKLYYSFQDDEFLYLIMEYLPG 869 +YA+K LKK +++ VE E+ +L A++ L+ FQ + L+ +ME++ G Sbjct: 349 ELYAIKILKKDVIIQDDDVECTMTEKRVLGLPSKPAFLTALHSCFQTMDRLFFVMEFVNG 408 Query: 870 GDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXF 1049 GD+M + + E A FY AE + + +H I+RD+K DN F Sbjct: 409 GDLMFQIQKVGKFREPHAVFYAAEIAVGLFYLHSQGVIYRDLKLDNVLVDAEGHIKIADF 468 Query: 1050 GLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLA 1229 G+CK ++NE D T Sbjct: 469 GMCK-------EHMNEGDTT---------------------------------------- 481 Query: 1230 YSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRS 1409 + GTPDYIAPE++ + YG DWW+ G ++YEML G PPF ED + I+ Sbjct: 482 RTFCGTPDYIAPEIVAYQPYGKAVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIM---E 538 Query: 1410 HL-KFPEEAKLSSET--KDLISKLLCNVEQRLGT--KGAHEIKAHTWFRGVQWEKL--YQ 1568 H+ +P+ S T K ++K + +RLG+ G +I+ H +FR + WEKL + Sbjct: 539 HVPSYPKSMSRESVTMCKGFLTK---HPGKRLGSGPTGEQDIREHQFFRRIDWEKLANRE 595 Query: 1569 MKAAFVPEVNGELDTQNFEKF 1631 ++ FVP V +NF+ + Sbjct: 596 IQPPFVPSVRNPRAAENFDPY 616
>P16054:KPCE_MOUSE Protein kinase C epsilon type - Mus musculus (Mouse)| Length = 737 Score = 155 bits (393), Expect = 5e-37 Identities = 111/433 (25%), Positives = 190/433 (43%), Gaps = 8/433 (1%) Frame = +3 Query: 354 GKDPGKPPVDDAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPA 533 G + +P ++PS + K A + ++K L++ + + + ++ + Sbjct: 326 GAESPQPASGNSPSEDDRSKSAPTSPCDQ-----ELKELENNIRKALSFDNRGEEHRASS 380 Query: 534 EEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKK 713 + E E + +R +G+++F + ++G+G+FG+V L K VYA+K Sbjct: 381 ATDGQLASPGENGEVRPGQAKR--LGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKV 438 Query: 714 LKKSEMLRRGQVEHVKAERNLLAEVDS-AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLL 890 LKK +L+ V+ E+ +LA Y+ +LY FQ + L+ +MEY+ GGD+M + Sbjct: 439 LKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQI 498 Query: 891 MRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLD 1070 R E ++FY AE A+ +H+H I+RD+K DN FG+CK Sbjct: 499 QRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCK--- 555 Query: 1071 SSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTP 1250 + + + + T P Sbjct: 556 ------------------EGIMNGVTTTTFCGTP-------------------------- 571 Query: 1251 DYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEE 1430 DYIAPE+L + YG DWW+LG +MYEM+ G PPF +++ I++ + +P Sbjct: 572 DYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILH--DDVLYP-- 627 Query: 1431 AKLSSETKDLISKLLC-NVEQRLG----TKGAHEIKAHTWFRGVQWEKLYQ--MKAAFVP 1589 LS E ++ + N +RLG G IK H +F+ + W L Q +K F P Sbjct: 628 VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKP 687 Query: 1590 EVNGELDTQNFEK 1628 + + D NF++ Sbjct: 688 RIKTKRDVNNFDQ 700
>Q03042:KGP1_DROME cGMP-dependent protein kinase, isozyme 1 - Drosophila melanogaster| (Fruit fly) Length = 768 Score = 155 bits (392), Expect = 6e-37 Identities = 97/358 (27%), Positives = 173/358 (48%), Gaps = 7/358 (1%) Frame = +3 Query: 579 EYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCR--EKTSRSVYAMKKLKKSEMLRRGQVE 752 E ++ + + + D E+++ +G G FG V L + + ++A+K LKK ++ Q E Sbjct: 443 EQLQQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEE 502 Query: 753 HVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFY 932 H+ +ER+++ S +I +LY +F+D++++Y+++E GG++ T+L + + ++ A+F Sbjct: 503 HIFSERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFI 562 Query: 933 IAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTP 1112 I + A E +H I+RD+KP+N FG K + +S+ Sbjct: 563 IGCVLQAFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSS----------- 611 Query: 1113 GKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYG 1292 ++ GTP+Y+APE++L KG+ Sbjct: 612 -------------------------------------KTWTFCGTPEYVAPEIILNKGHD 634 Query: 1293 MECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKL 1472 D+W+LG +++E+L G PPF + DPM T I+ + FP+ +S LI +L Sbjct: 635 RAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKH--ISRWAVQLIKRL 692 Query: 1473 LCNV-EQRLG--TKGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEKF 1631 +V +RLG T G +IK H WF G W+ L + FV + D + F++F Sbjct: 693 CRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDRF 750
>Q9V3I5:JIL1_DROME Chromosomal serine/threonine-protein kinase JIL-1 - Drosophila| melanogaster (Fruit fly) Length = 1207 Score = 154 bits (389), Expect = 1e-36 Identities = 113/386 (29%), Positives = 177/386 (45%), Gaps = 12/386 (3%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRS---VYAMKKLKKSEML-RRGQVEHVKAERN 773 + + DF+++ ++G GA+G V L R+ T +YAMK L K ++ +R EH K ER Sbjct: 256 VSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERV 315 Query: 774 LLAEVD-SAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVL 950 +L + + ++V L+Y+FQ LYL++++ GG++ T L + E + YIAE VL Sbjct: 316 VLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVL 375 Query: 951 AIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKP 1130 A+E +H+ I+RDIK +N FGL K L + N Sbjct: 376 ALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAEN----------------- 418 Query: 1131 LPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLL--KKGYGMECD 1304 A+S GT +Y+APE++ G+ D Sbjct: 419 -----------------------------EYRAHSFCGTLEYMAPEIIRTGPPGHDSAVD 449 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CN 1481 WWS+G + +E+L G PF + D +I + + S+ +D + K+L N Sbjct: 450 WWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKN 509 Query: 1482 VEQRLG--TKGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGAQ 1649 ++RLG + A EIK H +F G+ W++L + KA + P + E D QNF E T Sbjct: 510 PKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSN-EFTDQV 568 Query: 1650 VQSSSKAGPWRKMLPSKDANFVGYTY 1727 + P PS+ F GYTY Sbjct: 569 PEDPECDAP-----PSRIRLFRGYTY 589 Score = 54.7 bits (130), Expect = 2e-06 Identities = 67/279 (24%), Positives = 111/279 (39%), Gaps = 11/279 (3%) Frame = +3 Query: 555 KHLEKK------ETEYMR--LQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMK 710 +HLE+ E +Y LQ +D EL T GA+G + ++ V+ K Sbjct: 593 EHLEQMRRDNHCEIQYFNTGLQNIPCRPDDLELGTRTSNGAYGTCHFVVDSSTDLVFLAK 652 Query: 711 KLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLL 890 + S+ R +V+ + + L + IV + +F++ +++MEYL G ++ T Sbjct: 653 IIPLSKF-RPSEVDALIS--CALDTTNHKNIVSYHGTFREKCETWIVMEYLSGPEL-TAS 708 Query: 891 MRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLD 1070 +R D ED + + V+A+ IH ++IH D+KP+N Sbjct: 709 IRMD---EDSCREIFLQLVMAVRHIHSKHFIHGDLKPENIM------------------- 746 Query: 1071 SSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTP 1250 F N D T +L + + + W+ R T Sbjct: 747 ---FENRE--------------DRTVKLIDFGS--ACYNNRFKSWKDKPRY-------TL 780 Query: 1251 DYIAPEVLLKKG---YGMECDWWSLGAIMYEMLVGYPPF 1358 DY PE+L Y D + LGA +Y MLVG+ P+ Sbjct: 781 DYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPY 819
>Q6P5Z2:PKN3_HUMAN Serine/threonine-protein kinase N3 - Homo sapiens (Human)| Length = 889 Score = 154 bits (388), Expect = 2e-36 Identities = 108/346 (31%), Positives = 164/346 (47%), Gaps = 8/346 (2%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVD 791 ++DF L ++GRG FG+V L + K + YA+K LKK E+L R ++E + E+ +L V Sbjct: 556 LQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVG 615 Query: 792 SA---YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 +++ L FQ + E++PGGD+M + + +D E +A+FY+A VL ++ Sbjct: 616 CTGHPFLLSLLACFQTSSHACFVTEFVPGGDLM-MQIHEDVFPEPQARFYVACVVLGLQF 674 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H+ I+RD+K DN FGLCK G G D Sbjct: 675 LHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCK----------------EGIG---FGDR 715 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 TS + GTP+++APEVL ++ Y DWW LG Sbjct: 716 TS----------------------------TFCGTPEFLAPEVLTQEAYTRAVDWWGLGV 747 Query: 1323 IMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNV-EQRLG 1499 ++YEMLVG PF P T ++ + ++ P LS + + I KLL E+RLG Sbjct: 748 LLYEMLVGECPF----PGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLLQKCPEKRLG 803 Query: 1500 T--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFE 1625 + A EIK +FR W+ L ++ FVP + G D + FE Sbjct: 804 AGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFE 849
>P09217:KPCZ_RAT Protein kinase C zeta type - Rattus norvegicus (Rat)| Length = 592 Score = 154 bits (388), Expect = 2e-36 Identities = 113/397 (28%), Positives = 193/397 (48%), Gaps = 13/397 (3%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G++DF+L+ +IGRG++ +V L R K + +YAMK +KK + ++ V+ E+++ + Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQ 306 Query: 786 VDS-AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 S ++V L+ FQ L+L++EY+ GGD+M + R+ L E+ A+FY AE +A+ Sbjct: 307 ASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNF 366 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H+ I+RD+K DN +G+CK +G P D Sbjct: 367 LHERGIIYRDLKLDNVLLDADGHIKLTDYGMCK------------------EGLGP-GDT 407 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 TS + GTP+YIAPE+L + YG DWW+LG Sbjct: 408 TS----------------------------TFCGTPNYIAPEILRGEEYGFSVDWWALGV 439 Query: 1323 IMYEMLVGYPPF--YSEDP-MSTCRKI--VNWRSHLKFPE--EAKLSSETKDLISKLLCN 1481 +M+EM+ G PF +++P M+T + V ++ P K S K ++K + Sbjct: 440 LMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNK---D 496 Query: 1482 VEQRLGTK---GAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGA 1646 ++RLG + G +IK+H +FR + W+ L Q F P++ + NF+ + T Sbjct: 497 PKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQITDDYGLDNFDT-QFTSE 555 Query: 1647 QVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDE 1757 VQ + K + + F G+ Y N +++ +E Sbjct: 556 PVQLTPDDEDVIKRIDQSE--FEGFEYINPLLLSAEE 590
>Q02956:KPCZ_MOUSE Protein kinase C zeta type - Mus musculus (Mouse)| Length = 592 Score = 154 bits (388), Expect = 2e-36 Identities = 113/397 (28%), Positives = 193/397 (48%), Gaps = 13/397 (3%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G++DF+L+ +IGRG++ +V L R K + +YAMK +KK + ++ V+ E+++ + Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQ 306 Query: 786 VDS-AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 S ++V L+ FQ L+L++EY+ GGD+M + R+ L E+ A+FY AE +A+ Sbjct: 307 ASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNF 366 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H+ I+RD+K DN +G+CK +G P D Sbjct: 367 LHERGIIYRDLKLDNVLLDADGHIKLTDYGMCK------------------EGLGP-GDT 407 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 TS + GTP+YIAPE+L + YG DWW+LG Sbjct: 408 TS----------------------------TFCGTPNYIAPEILRGEEYGFSVDWWALGV 439 Query: 1323 IMYEMLVGYPPF--YSEDP-MSTCRKI--VNWRSHLKFPE--EAKLSSETKDLISKLLCN 1481 +M+EM+ G PF +++P M+T + V ++ P K S K ++K + Sbjct: 440 LMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNK---D 496 Query: 1482 VEQRLGTK---GAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGA 1646 ++RLG + G +IK+H +FR + W+ L Q F P++ + NF+ + T Sbjct: 497 PKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQITDDYGLDNFDT-QFTSE 555 Query: 1647 QVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDE 1757 VQ + K + + F G+ Y N +++ +E Sbjct: 556 PVQLTPDDEDVIKRIDQSE--FEGFEYINPLLLSAEE 590
>P43057:KPC1_CANAL Protein kinase C-like 1 - Candida albicans (Yeast)| Length = 1097 Score = 154 bits (388), Expect = 2e-36 Identities = 109/418 (26%), Positives = 191/418 (45%), Gaps = 18/418 (4%) Frame = +3 Query: 429 QYIENHYKTQMKSLQDRKERRWMLE-------RKLQDAEVPAEEQNNILKHLEKK---ET 578 +Y EN T ++ Q R ++ K Q+ +V +Q L H ++ Sbjct: 696 KYTENEILTDVQQDQVRSPFADQIQGVPETSHAKQQNQQVQQVQQQEELGHQRTHSSGKS 755 Query: 579 EYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHV 758 + ++ K+G++DF+ L ++G+G FG+V L + + + A+K LKK ++ + E V Sbjct: 756 GKSKRRKRKVGLDDFQFLAVLGKGNFGKVMLAESRHTSKLCAIKVLKKDFIVENDEAESV 815 Query: 759 KAERNLLAEVDS---AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKF 929 K+E+ + + +++ L+ FQ + +Y +MEY+ GGD+M + +K+ T AKF Sbjct: 816 KSEKRVFLTANKEMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHI-QKNRFTAKRAKF 874 Query: 930 YIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYT 1109 Y E +L ++ H + ++RD+K DN +GLCK Sbjct: 875 YACEVLLGLKYFHDNGIVYRDLKLDNILLTTKGHIKIGDYGLCKE--------------- 919 Query: 1110 PGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGY 1289 W K+ + GTP+++APE++ K Y Sbjct: 920 -----------------------------DMWHKS---TTSTFCGTPEFMAPEIVAGKAY 947 Query: 1290 GMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISK 1469 DWW+ G ++++ML+ PF +D I N +K+P LS +T ++ Sbjct: 948 DRSVDWWAFGVLLFQMLLCQSPFKGDDEDDIFNAIEN--DEVKYP--INLSRQTVLVLQA 1003 Query: 1470 LLC-NVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFEK 1628 LL + QRLG+ K A EI H +F V ++ + ++ A ++PEV E D NF+K Sbjct: 1004 LLTKDPSQRLGSGPKDAEEIMEHPYFHDVNFDDVLNCRIPAPYIPEVQSEHDYSNFDK 1061
>P05771:KPCB_HUMAN Protein kinase C beta type - Homo sapiens (Human)| Length = 671 Score = 153 bits (386), Expect = 3e-36 Identities = 114/419 (27%), Positives = 187/419 (44%), Gaps = 8/419 (1%) Frame = +3 Query: 513 QDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSR 692 Q +VP E+ N + + R +M + DF L ++G+G+FG+V L K + Sbjct: 312 QGTKVPEEKTTNTVSKFDNNGN------RDRMKLTDFNFLMVLGKGSFGKVMLSERKGTD 365 Query: 693 SVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA-YIVKLYYSFQDDEFLYLIMEYLPG 869 +YA+K LKK +++ VE E+ +LA ++ +L+ FQ + LY +MEY+ G Sbjct: 366 ELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNG 425 Query: 870 GDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXF 1049 GD+M + + E A FY AE + + + I+RD+K DN F Sbjct: 426 GDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADF 485 Query: 1050 GLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLA 1229 G+CK + + D + T P Sbjct: 486 GMCK---------------------ENIWDGVTTKTFCGTP------------------- 505 Query: 1230 YSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRS 1409 DYIAPE++ + YG DWW+ G ++YEML G PF ED + I+ Sbjct: 506 -------DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIM--EH 556 Query: 1410 HLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHTWFRGVQWEKL--YQMK 1574 ++ +P+ +S E + L+ + +RL G +G +IK H +FR + WEKL +++ Sbjct: 557 NVAYPK--SMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQ 614 Query: 1575 AAFVPEVNGELDTQNFEK-FEETGAQVQSSSKAGPWRKMLPSKDAN-FVGYTYKNFEIV 1745 + P+ + DT NF+K F ++ + K + + D N F G++Y N E V Sbjct: 615 PPYKPKARDKRDTSNFDKEFTRQPVELTPTDKL-----FIMNLDQNEFAGFSYTNPEFV 668
>P34722:KPC1_CAEEL Protein kinase C-like 1 - Caenorhabditis elegans| Length = 704 Score = 153 bits (386), Expect = 3e-36 Identities = 106/348 (30%), Positives = 157/348 (45%), Gaps = 7/348 (2%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 K + F LL ++G+G+FG+V L K YAMK LKK +L E ER +L Sbjct: 369 KFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLI 428 Query: 783 EVDSA-YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 ++ +L+ SFQ +E+L+ +MEYL GGD+M + + E +FY E V+A++ Sbjct: 429 LASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQ 488 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPD 1139 +H +N I+RD+K DN FG+ K Sbjct: 489 FLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKT------------------------- 523 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRM-LAYSTVGTPDYIAPEVLLKKGYGMECDWWSL 1316 + NR +A + GTPDYI+PE++ + Y D+WS Sbjct: 524 ----------------------EMNRENGMASTFCGTPDYISPEIIKGQLYNEAVDFWSF 561 Query: 1317 GAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQR 1493 G +MYEMLVG PF+ E I+N R + FP+ +S E +S L N R Sbjct: 562 GVLMYEMLVGQSPFHGEGEDELFDSILNERPY--FPK--TISKEAAKCLSALFDRNPNTR 617 Query: 1494 LGTKGAHE--IKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFE 1625 LG + I+ H +FRGV W++ Q+ F P + D NF+ Sbjct: 618 LGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASNFD 665
>O19111:KPCZ_RABIT Protein kinase C zeta type - Oryctolagus cuniculus (Rabbit)| Length = 591 Score = 152 bits (383), Expect = 7e-36 Identities = 112/397 (28%), Positives = 194/397 (48%), Gaps = 13/397 (3%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAE 785 +G++DF+L+ +IGRG++ +V L R K + VYAMK +KK + ++ V+ E+++ + Sbjct: 246 LGLQDFDLIRVIGRGSYAKVLLVRLKKNGQVYAMKVVKKELVHDDEDIDWVQTEKHVFEQ 305 Query: 786 VD-SAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 + ++V L+ FQ L+L++EY+ GGD+M + R+ L E+ A+FY AE +A+ Sbjct: 306 ASGNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNF 365 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H+ I+RD+K DN +G+CK +G P D Sbjct: 366 LHERGIIYRDLKLDNVLLDADGHIKLTDYGMCK------------------EGLGP-GDT 406 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 TS + GTP+YIAPE+L + YG DWW+LG Sbjct: 407 TS----------------------------TFCGTPNYIAPEILRGEEYGFSVDWWALGV 438 Query: 1323 IMYEMLVGYPPF--YSEDP-MSTCRKI--VNWRSHLKFPE--EAKLSSETKDLISKLLCN 1481 +M+EM+ G PF +++P M+T + V ++ P K S K ++K + Sbjct: 439 LMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNK---D 495 Query: 1482 VEQRLGTK---GAHEIKAHTWFRGVQWEKLYQMKA--AFVPEVNGELDTQNFEKFEETGA 1646 ++RLG + G +IK+H +FR + W+ L + +A F P++ + N + + T Sbjct: 496 PKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNSDT-QFTSE 554 Query: 1647 QVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDE 1757 VQ + K + + F G+ Y N +++ +E Sbjct: 555 PVQLTPDDEDVIKRIDQSE--FEGFEYINPLLLSTEE 589
>P05772:KPCB_RABIT Protein kinase C beta type - Oryctolagus cuniculus (Rabbit)| Length = 671 Score = 152 bits (383), Expect = 7e-36 Identities = 117/435 (26%), Positives = 192/435 (44%), Gaps = 10/435 (2%) Frame = +3 Query: 471 QDRKERRWMLERKL--QDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIG 644 + +E R ER Q + P E+ N + + R +M + DF L ++G Sbjct: 296 EGNEELRQKFERAKIGQGTKTPEEKTTNTISKFDNNGN------RDRMKLTDFNFLMVLG 349 Query: 645 RGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA-YIVKLYYS 821 +G+FG+V L K + +YA+K LKK +++ VE E+ +LA ++ +L+ Sbjct: 350 KGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSC 409 Query: 822 FQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKP 1001 FQ + LY +MEY+ GGD+M + + E A FY AE + + + I+RD+K Sbjct: 410 FQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKL 469 Query: 1002 DNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRT 1181 DN FG+CK + + D + T P Sbjct: 470 DNVMLDSEGHIKIADFGMCK---------------------ENIWDGVTTKTFCGTP--- 505 Query: 1182 QQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFY 1361 DYIAPE++ + YG DWW+ G ++YEML G PF Sbjct: 506 -----------------------DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFE 542 Query: 1362 SEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHT 1532 ED + I+ ++ +P+ +S E + L+ + +RL G +G +IK H Sbjct: 543 GEDEDELFQSIM--EHNVAYPK--SMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKDHA 598 Query: 1533 WFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEK-FEETGAQVQSSSKAGPWRKMLPSKD 1703 +FR + WEKL +++ + P+ + DT NF+K F ++ + K + + D Sbjct: 599 FFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKL-----FIMNLD 653 Query: 1704 AN-FVGYTYKNFEIV 1745 N F G++Y N E V Sbjct: 654 QNEFAGFSYTNPEFV 668
>P68403:KPCB_RAT Protein kinase C beta type - Rattus norvegicus (Rat)| Length = 671 Score = 151 bits (382), Expect = 9e-36 Identities = 117/435 (26%), Positives = 192/435 (44%), Gaps = 10/435 (2%) Frame = +3 Query: 471 QDRKERRWMLERKL--QDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIG 644 + +E R ER Q + P E+ N + + R +M + DF L ++G Sbjct: 296 EGNEELRQKFERAKIGQGTKAPEEKTANTISKFDNNGN------RDRMKLTDFNFLMVLG 349 Query: 645 RGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA-YIVKLYYS 821 +G+FG+V L K + +YA+K LKK +++ VE E+ +LA ++ +L+ Sbjct: 350 KGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSC 409 Query: 822 FQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKP 1001 FQ + LY +MEY+ GGD+M + + E A FY AE + + + I+RD+K Sbjct: 410 FQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKL 469 Query: 1002 DNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRT 1181 DN FG+CK + + D + T P Sbjct: 470 DNVMLDSEGHIKIADFGMCK---------------------ENIWDGVTTKTFCGTP--- 505 Query: 1182 QQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFY 1361 DYIAPE++ + YG DWW+ G ++YEML G PF Sbjct: 506 -----------------------DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFE 542 Query: 1362 SEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHT 1532 ED + I+ ++ +P+ +S E + L+ + +RL G +G +IK H Sbjct: 543 GEDEDELFQSIM--EHNVAYPK--SMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHA 598 Query: 1533 WFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEK-FEETGAQVQSSSKAGPWRKMLPSKD 1703 +FR + WEKL +++ + P+ + DT NF+K F ++ + K + + D Sbjct: 599 FFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKL-----FIMNLD 653 Query: 1704 AN-FVGYTYKNFEIV 1745 N F G++Y N E V Sbjct: 654 QNEFAGFSYTNPEFV 668
>P15792:KPK1_PHAVU Protein kinase PVPK-1 - Phaseolus vulgaris (Kidney bean) (French| bean) Length = 609 Score = 150 bits (380), Expect = 2e-35 Identities = 111/375 (29%), Positives = 174/375 (46%), Gaps = 38/375 (10%) Frame = +3 Query: 585 MRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKA 764 +R + + + F LL +G G G V L +R+ +AMK + K+E+ R ++ + Sbjct: 217 VRTRDGMLEMRHFRLLKKLGCGDIGSVYLAELSGTRTSFAMKVMNKTELANRKKLLRAQT 276 Query: 765 ERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRK--DTLTEDEAKFYIA 938 ER +L +D ++ LY F+ + F L+ME+ PGGD+ L R+ +E +FY+A Sbjct: 277 EREILQSLDHPFLPTLYTHFETEIFSCLVMEFCPGGDLHALRQRQPGKYFSEHAVRFYVA 336 Query: 939 ETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGL---CKP----LDSSN------ 1079 E +L++E +H I+RD+KP+N F L C + SSN Sbjct: 337 EVLLSLEYLHMLGIIYRDLKPENVLVREDGHIMLSDFDLSLRCSVSPTLVKSSNNLQTKS 396 Query: 1080 ---------------------FPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQL 1196 P+ P + GK K D S+ N + T +L Sbjct: 397 SGYCVQPSCIEPTCVMQPDCIKPSCFTPRFLSGKSKK---DKKSKPKNDMHNQVTPLPEL 453 Query: 1197 SHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPM 1376 N R +++ VGT +Y+APE++ +G+G DWW+ G +YE+L G PF Sbjct: 454 IAEPTNARSMSF--VGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGRTPFKGSANR 511 Query: 1377 STCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQ-RLG-TKGAHEIKAHTWFRGVQ 1550 +T ++ L+FPE +S +DLI LL Q RL +GA EIK H +F+ V Sbjct: 512 ATLFNVIG--QPLRFPESPTVSFAARDLIRGLLVKEPQHRLAYRRGATEIKQHPFFQNVN 569 Query: 1551 WEKLYQMKAAFVPEV 1595 W + + A PEV Sbjct: 570 WALI---RCATPPEV 581
>O43930:PRKY_HUMAN Serine/threonine-protein kinase PRKY - Homo sapiens (Human)| Length = 277 Score = 150 bits (378), Expect = 3e-35 Identities = 78/280 (27%), Positives = 135/280 (48%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVD 791 ++D + L +G G FG V L +EKT++ +A+K + +++RR Q +HV E+++L EV Sbjct: 46 LQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVS 105 Query: 792 SAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHK 971 ++++L++++ ++ FLY++MEY+PGG++ + L + + FY AE + AIE +H Sbjct: 106 HPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHS 165 Query: 972 HNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSR 1151 ++RD+KP+N FG K L + P+Y Sbjct: 166 KEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEY--------------- 210 Query: 1152 LTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 1331 +APEV+ KG+G DWW+LG +++ Sbjct: 211 -----------------------------------LAPEVIQSKGHGRAVDWWALGILIF 235 Query: 1332 EMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSET 1451 EML G+PPF+ ++P +KI+ L FP +T Sbjct: 236 EMLSGFPPFFDDNPFGIYQKIL--AGKLYFPRHLDFHVKT 273
>P90980:KPC2_CAEEL Protein kinase C-like 2 - Caenorhabditis elegans| Length = 682 Score = 150 bits (378), Expect = 3e-35 Identities = 108/389 (27%), Positives = 174/389 (44%), Gaps = 12/389 (3%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDS- 794 DF LT++G+G+FG+V L +KT++ ++A+K LKK +++ VE E+ +LA + Sbjct: 347 DFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKP 406 Query: 795 AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKH 974 +++V L+ FQ + LY +ME++ GGD+M + + E A FY AE + + +H Sbjct: 407 SFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSK 466 Query: 975 NYIHRDIKPDNXXXXXXXXXXXXXFGLCKPL---DSSNFPNLNEPDYTPGKGAKPLPDNT 1145 I+RD+K DN FG+CK D++ PDY Sbjct: 467 GIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDY------------- 513 Query: 1146 SRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAI 1325 IAPE++L + YG DWW+ G + Sbjct: 514 -------------------------------------IAPEIILYQPYGKSVDWWAYGVL 536 Query: 1326 MYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRLGT 1502 ++EML G PPF ED I ++ +P+ LS E L LL N +RLG Sbjct: 537 LFEMLAGQPPFDGEDEDELFTAIT--EHNVSYPK--SLSKEAVSLCKALLIKNPSKRLGC 592 Query: 1503 KG-----AHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGAQVQSS 1661 G + +IK H +FR + W K+ Q++ F P++ + T+N F+ + ++ + Sbjct: 593 TGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRSTEN---FDHSFLKLPTK 649 Query: 1662 SKAGPWRKMLPSKDANFVGYTYKNFEIVN 1748 W + N G + NF VN Sbjct: 650 MTPPDWEVL-----ENLKGDEFSNFSFVN 673
>Q8K045:PKN3_MOUSE Serine/threonine-protein kinase N3 - Mus musculus (Mouse)| Length = 878 Score = 147 bits (371), Expect = 2e-34 Identities = 108/346 (31%), Positives = 160/346 (46%), Gaps = 8/346 (2%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVD 791 ++DF L ++GRG FG+V L + K + YA+K LKK E+L R +++ + E+ +L V Sbjct: 545 LQDFRCLAVLGRGHFGKVLLVQYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRILETVG 604 Query: 792 SA---YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 +++ L Q + E+LPGGD+M + +D E +A FY+A VL ++ Sbjct: 605 RTGHPFLLSLLACLQTSSHACFVTEFLPGGDLMAQI-HEDVFPEPQACFYLACVVLGLQF 663 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H+ I+RD+K DN FGLCK G G D Sbjct: 664 LHEKRIIYRDLKLDNLLLDAQGFLKIADFGLCK----------------EGIG---FGDR 704 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 TS + GTP+++APEVL ++ Y DWW LG Sbjct: 705 TS----------------------------TFCGTPEFLAPEVLTQEAYTRAVDWWGLGV 736 Query: 1323 IMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLG 1499 ++YEMLVG PF P T ++ P LS + +LI KLL + E+RLG Sbjct: 737 LLYEMLVGECPF----PGDTEEEVFECIVSADVPCPHFLSVQGLELIQKLLQKSPEKRLG 792 Query: 1500 T--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVPEVNGELDTQNFE 1625 + A EIK +FR W+ L ++ FVP + G D + FE Sbjct: 793 AGERDAEEIKVQPFFRTTNWQALLARTVQPPFVPTLCGPADLRYFE 838
>O94324:PPK31_SCHPO Serine/threonine-protein kinase ppk31 - Schizosaccharomyces pombe| (Fission yeast) Length = 1032 Score = 145 bits (367), Expect = 5e-34 Identities = 108/390 (27%), Positives = 174/390 (44%), Gaps = 51/390 (13%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAE-RNLLAEV 788 +++F LL I RGA+G V L ++++S +A+K + KS + +++ + E RN+ + Sbjct: 525 LDEFILLKEINRGAYGRVYLAKKRSSGKYFALKMIPKSSLDSLKKIKGLLLEKRNMHIQR 584 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 VKLYY+F ++L L+M+Y GGD TL+ + L E Y AE + AIE +H Sbjct: 585 YGPNTVKLYYAFDSGDYLCLVMDYFNGGDCETLIQKLGPLPEQWVCQYAAELLNAIELLH 644 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSN------------------FPNLN 1094 + IH DIKP N FGL + ++ + L Sbjct: 645 QDGIIHHDIKPANMLVDETGHIRLTDFGLSENVEEKKEVYKLTKRMSFEQKHGNLYEQLQ 704 Query: 1095 EPDYTPGKGAKPLPDNTSRLTNPSAPKRTQ---QEQLSHW-------------------- 1205 + + + N L +P++ + + H Sbjct: 705 PKKFEFVRYVRNYRGNIDELEKAESPQQNSDYANDSVQHLLDFDINNMDETAIHMLMNQL 764 Query: 1206 --QKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMS 1379 ++NR + GTP+Y+APE+L+ M D W++G +++EML G PF + + Sbjct: 765 EKKENRTFIKKDISGTPNYMAPEILMGVDTQMG-DIWAMGCVIFEMLTGTRPFEANTVKA 823 Query: 1380 TCRKI----VNWRSHLKFPEEAKLSSETKDLISKLL---CNVEQRLGTKGAHEIKAHTWF 1538 +I + W +K S E DLI+KL+ CN +RLG+ G EIK H +F Sbjct: 824 IWARIERNDIGWTKRVK----ESCSKEAVDLITKLMDPDCN--KRLGSNGYQEIKKHPFF 877 Query: 1539 RGVQWEKLYQMKAAFVPEVNGELDTQNFEK 1628 R ++W+ L FVP+ D FEK Sbjct: 878 RTIKWDNLNSGPGPFVPQTENVEDLTYFEK 907
>Q5PU49:KPCD_CANFA Protein kinase C delta type - Canis familiaris (Dog)| Length = 674 Score = 145 bits (367), Expect = 5e-34 Identities = 108/383 (28%), Positives = 174/383 (45%), Gaps = 6/383 (1%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 + +++F ++G+G+FG+V L K + +A+K LKK +L VE E+ +LA Sbjct: 341 RCNIDNFIFHKVLGKGSFGKVLLVELKGKKEFFAIKALKKDVVLIDDDVECTMVEKRVLA 400 Query: 783 EV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 ++ ++ L+ +FQ + L+ +ME+L GGD+M + K A FY AE V ++ Sbjct: 401 LAWENPFLTHLFCTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIVCGLQ 460 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPD 1139 +H I+RD+K DN FG+CK Sbjct: 461 FLHNKGIIYRDLKLDNVMLDQDGHIKIADFGMCK-------------------------- 494 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLG 1319 N K+ A + GTPDYIAPE+L Y DWWS G Sbjct: 495 -----ENIFGEKQ----------------ASTFCGTPDYIAPEILQGLKYSFSVDWWSFG 533 Query: 1320 AIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRL 1496 ++YEML+G PF+ +D I H +P ++ E+KD++ KLL + +RL Sbjct: 534 VLLYEMLIGQSPFHGDDEDELFESIRVDTPH--YPR--WITKESKDILEKLLERDTTKRL 589 Query: 1497 GTKGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNF-EKFEETGAQVQSSSK 1667 G G IK H +F+ + W L + ++ F P+V D NF ++F A++ + K Sbjct: 590 GVTG--NIKIHPFFKTINWTLLEKRAVEPPFKPKVKSPGDYSNFDQEFLNEKARLSYTDK 647 Query: 1668 AGPWRKMLPSKDAN-FVGYTYKN 1733 ++ S D F G+++ N Sbjct: 648 -----NLIDSMDQTAFAGFSFVN 665
>P83099:KPC4_DROME Putative protein kinase C delta type homolog - Drosophila| melanogaster (Fruit fly) Length = 671 Score = 145 bits (366), Expect = 6e-34 Identities = 116/395 (29%), Positives = 178/395 (45%), Gaps = 15/395 (3%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA-EV 788 V+DF L ++G+G+FG+V L + + YA+K LKK +L V+ ER +LA Sbjct: 340 VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGT 399 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 Y+ L+ +FQ + L+ +MEYL GGD+M + +E+ A+FY AE + ++ +H Sbjct: 400 KHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLH 459 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCK---PLDSSNFPNLNEPDYTPGKGAKPLPD 1139 K I+RD+K DN FG+CK LD + PDY Sbjct: 460 KKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDY----------- 508 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLG 1319 +APE++ + Y DWWS G Sbjct: 509 ---------------------------------------MAPEIIKGEKYNQNVDWWSFG 529 Query: 1320 AIMYEMLVGYPPF--YSEDPM--STCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNV 1484 ++YEML+G PF ED + S C +I W FP +S+E ++ LL + Sbjct: 530 VLLYEMLIGQSPFSGCDEDELFWSICNEI-PW-----FP--VYISAEATGILKGLLEKDY 581 Query: 1485 EQRLGTK--GAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEK-FEETGAQ 1649 +R+G++ A +I H +FR + W L Q++ F P+V LDTQ F++ F + Sbjct: 582 TKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVR 641 Query: 1650 VQSSSKAGPWRKMLPSKD-ANFVGYTYKNFEIVND 1751 + K ++L S D F G+TY N I D Sbjct: 642 LTPIDK-----EILASMDQKQFHGFTYTNPHITLD 671
>Q09639:GRK2_CAEEL G protein-coupled receptor kinase 2 - Caenorhabditis elegans| Length = 707 Score = 145 bits (366), Expect = 6e-34 Identities = 131/439 (29%), Positives = 196/439 (44%), Gaps = 20/439 (4%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 ++ + DF + IIGRG FGEV CR+ + +YAMK L K + + ER +L+ Sbjct: 185 QLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLS 244 Query: 783 EV----DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVL 950 V D +IV + Y+FQ + L I++ + GGD+ L + TE E FY +E +L Sbjct: 245 LVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFYASEVIL 304 Query: 951 AIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKP 1130 +E +H ++RD+KP N GL DY+ K Sbjct: 305 GLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLAC-------------DYSKKK---- 347 Query: 1131 LPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKK-GYGMECDW 1307 +++VGT Y+APEVL K Y DW Sbjct: 348 --------------------------------PHASVGTHGYMAPEVLAKGVAYDSSADW 375 Query: 1308 WSLGAIMYEMLVGYPPF---YSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL- 1475 +SLG ++Y++L G+ PF S+D + + ++ P E LS + +DL+ LL Sbjct: 376 FSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMTLT--QDIELPNEG-LSKDCRDLLEGLLK 432 Query: 1476 CNVEQRLGT--KGAHEIKAHTWFRGVQWEKLY--QMKAAFVP---EVNG--ELDTQNFEK 1628 +V RLG KG E+K H +F+ V W+ +Y +M +P EVN D NF+ Sbjct: 433 RDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYLRRMTPPLIPPRGEVNAADAFDIGNFDD 492 Query: 1629 FEETGAQVQ--SSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDDEVAGIAELKKKSSKSK 1802 E G ++Q S + ++ + N + T FE+VN D A AE KK+S + Sbjct: 493 DEVKGVKLQDGDSDLYKNFNIVISERWQNEIAETI--FEVVNQD--ADKAESKKRSKQK- 547 Query: 1803 RPTIKTLFESMDEDEPVHG 1859 IK E D D VHG Sbjct: 548 ---IKVAVEEKDSDVIVHG 563
>Q03407:PKH1_YEAST Serine/threonine-protein kinase PKH1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 766 Score = 145 bits (365), Expect = 8e-34 Identities = 98/320 (30%), Positives = 158/320 (49%), Gaps = 2/320 (0%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 KMG++DF+ +G G++ V L + S YA+K L K ++R+ +V++V E+ L Sbjct: 119 KMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQ 178 Query: 783 EVDSAY-IVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 +++ I KL+++FQD+ LY ++EY P GD + L+ + +L E A++Y ++ + A++ Sbjct: 179 KLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVD 238 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPD 1139 S+H IHRDIKP+N FG K L EP T KP D Sbjct: 239 SLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILP-------EEPSNT--ADGKPYFD 289 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLG 1319 ++ + S VGT +Y++PE+L CD W+ G Sbjct: 290 LYAK-------------------------SKSFVGTAEYVSPELLNDNYTDSRCDIWAFG 324 Query: 1320 AIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL 1496 I+Y+ML G PPF + + T +K++ +++ A KDL+ KLL + RL Sbjct: 325 CILYQMLAGKPPFKAANEYLTFQKVMK----IQYAFTAGFPQIVKDLVKKLLVRDPNDRL 380 Query: 1497 GTKGAHEIKAHTWFRGVQWE 1556 K +IKAH +F V +E Sbjct: 381 TIK---QIKAHLFFHEVNFE 397
>Q02156:KPCE_HUMAN Protein kinase C epsilon type - Homo sapiens (Human)| Length = 737 Score = 144 bits (364), Expect = 1e-33 Identities = 109/438 (24%), Positives = 188/438 (42%), Gaps = 13/438 (2%) Frame = +3 Query: 354 GKDPGKPPVDDAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPA 533 G + +P +PS + K A + ++K L++ + + + ++ + Sbjct: 326 GAESPQPASGSSPSEEDRSKSAPTSPCDQ-----EIKELENNIRKALSFDNRGEEHRAAS 380 Query: 534 EEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKK 713 ++ E E + +R +G+++F + ++G+G+FG+V L K VYA+K Sbjct: 381 SPDGQLMSPGENGEVRQGQAKR--LGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKV 438 Query: 714 LKKSEMLRRGQVEHVKAERNLLAEVDS-AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLL 890 LKK +L+ V+ E+ +LA Y+ +LY FQ + L+ +MEY+ GGD+M + Sbjct: 439 LKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQI 498 Query: 891 MRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP-- 1064 R E ++FY AE A+ +H+H I+RD+K DN FG+CK Sbjct: 499 QRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGI 558 Query: 1065 ---LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYS 1235 + ++ F PDY AP+ Q+ + Sbjct: 559 LNGVTTTTF--CGTPDYI-------------------APEILQELE-------------- 583 Query: 1236 TVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHL 1415 YG DWW+LG +MYEM+ G PPF +++ I++ + Sbjct: 584 -----------------YGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILH--DDV 624 Query: 1416 KFPEEAKLSSETKDLISKLLC-NVEQRLG----TKGAHEIKAHTWFRGVQWEKLYQ--MK 1574 +P LS E ++ + N +RLG G IK H +F+ + W L Q +K Sbjct: 625 LYP--VWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIK 682 Query: 1575 AAFVPEVNGELDTQNFEK 1628 F P + + D NF++ Sbjct: 683 PPFKPRIKTKRDVNNFDQ 700
>P28867:KPCD_MOUSE Protein kinase C delta type - Mus musculus (Mouse)| Length = 674 Score = 144 bits (364), Expect = 1e-33 Identities = 109/380 (28%), Positives = 170/380 (44%), Gaps = 6/380 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEV- 788 +E+F ++G+G+FG+V L K +A+K LKK +L VE E+ +LA Sbjct: 344 LENFTFQKVLGKGSFGKVLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEKRVLALAW 403 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 +S ++ L +FQ + L+ +ME+L GGD+M + K A FY AE + ++ +H Sbjct: 404 ESPFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLH 463 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 I+RD+K DN FG+CK E + G+ Sbjct: 464 SKGIIYRDLKLDNVMLDRDGHIKIADFGMCK-----------ENIFGEGR---------- 502 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 A + GTPDYIAPE+L Y DWWS G ++ Sbjct: 503 --------------------------ASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLL 536 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTK 1505 YEML+G PF+ +D I H +P ++ E+KD++ KL + ++RLG Sbjct: 537 YEMLIGQSPFHGDDEDELFESIRVDTPH--YPR--WITKESKDIMEKLFERDPDKRLGVT 592 Query: 1506 GAHEIKAHTWFRGVQWEKLYQMKA--AFVPEVNGELDTQNFE-KFEETGAQVQSSSKAGP 1676 G I+ H +F+ + W L + K F P+V D NF+ +F Q+ S K Sbjct: 593 G--NIRIHPFFKTINWSLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDK--- 647 Query: 1677 WRKMLPSKDAN-FVGYTYKN 1733 ++ S D F G+++ N Sbjct: 648 --NLIDSMDQEAFHGFSFVN 665
>Q19266:KPC3_CAEEL Protein kinase C-like 3 - Caenorhabditis elegans| Length = 597 Score = 144 bits (364), Expect = 1e-33 Identities = 98/357 (27%), Positives = 164/357 (45%), Gaps = 17/357 (4%) Frame = +3 Query: 606 MGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLL-A 782 + + DF LLT+IGRG++ +V ++R +YA+K +KK ++ V+ E+++ A Sbjct: 248 VSLNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEA 307 Query: 783 EVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIES 962 + ++V L+ FQ + L+ ++E++PGGD+M + ++ L E+ A+FY E +LA+ Sbjct: 308 ASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHF 367 Query: 963 IHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDN 1142 +H I+RD+K DN +G+CK N+ + D T Sbjct: 368 LHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCK-------ENIKDGDLTS---------- 410 Query: 1143 TSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGA 1322 + GTP+YIAPE+L YG DWW+LG Sbjct: 411 ------------------------------TFCGTPNYIAPEILRGDEYGFSVDWWALGV 440 Query: 1323 IMYEMLVGYPPF------YSEDPMSTCRKIVNWRSHLKFPE--EAKLSSETKDLISKLLC 1478 +M+EM+ G PF SE+ + ++ P + S K ++K Sbjct: 441 LMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNK--- 497 Query: 1479 NVEQRLGTK-----GAHEIKAHTWFRG-VQWEKLYQMKAA--FVPEVNGELDTQNFE 1625 + +RLG K G ++K H +FRG + WE L Q A + P V + D +F+ Sbjct: 498 DPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHPAVESDRDLTHFD 554
>Q12236:KOK0_YEAST Probable serine/threonine-protein kinase YOL100W - Saccharomyces| cerevisiae (Baker's yeast) Length = 1081 Score = 144 bits (364), Expect = 1e-33 Identities = 91/331 (27%), Positives = 168/331 (50%), Gaps = 2/331 (0%) Frame = +3 Query: 570 KETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQV 749 KE+ + K G++DF+ ++IG GA+ V L ++ YA K L K ++R+ +V Sbjct: 162 KESSKAQKNIIKKGIKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKV 221 Query: 750 EHVKAERNLLAEVD-SAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAK 926 ++V E+ L +++ S +V+L+ +FQD+ LY ++EY P GD ++L+ + +L E A+ Sbjct: 222 KYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCAR 281 Query: 927 FYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDY 1106 +Y A+ + AI+ +H + IHRDIKP+N FG K L+ +N ++++P+Y Sbjct: 282 YYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTN-NSVSKPEY 340 Query: 1107 TPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKG 1286 +K S VGT +Y++PE+L Sbjct: 341 DLSTRSK-----------------------------------SFVGTAEYVSPELLNDSF 365 Query: 1287 YGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLIS 1466 CD W+ G I+++M+ G PPF + + T +K++ +++ +DL+ Sbjct: 366 TDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMK----VQYAFTPGFPLIIRDLVK 421 Query: 1467 KLLC-NVEQRLGTKGAHEIKAHTWFRGVQWE 1556 K+L N+++RL +IK H +F+ + ++ Sbjct: 422 KILVKNLDRRLTIS---QIKEHHFFKDLNFK 449
>P09216:KPCE_RAT Protein kinase C epsilon type - Rattus norvegicus (Rat)| Length = 737 Score = 144 bits (362), Expect = 2e-33 Identities = 110/438 (25%), Positives = 187/438 (42%), Gaps = 13/438 (2%) Frame = +3 Query: 354 GKDPGKPPVDDAPSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPA 533 G + +P ++PS + K A + ++K L++ + + + ++ + Sbjct: 326 GAESPQPASGNSPSEDDRSKSAPTSPCDQ-----ELKELENNIRKALSFDNRGEEHRASS 380 Query: 534 EEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKK 713 + E E + +R +G+++F + ++G+G+FG+V L K VYA+K Sbjct: 381 STDGQLASPGENGEVRQGQAKR--LGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKV 438 Query: 714 LKKSEMLRRGQVEHVKAERNLLAEVDS-AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLL 890 LKK +L+ V+ E+ +LA Y+ +LY FQ + L+ +MEY+ GGD+M + Sbjct: 439 LKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQI 498 Query: 891 MRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP-- 1064 R E + FY AE A+ +H+H I+RD+K DN FG+CK Sbjct: 499 QRSRKFDEPRSGFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHSKLADFGMCKEGI 558 Query: 1065 ---LDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYS 1235 + ++ F PDY AP+ Q+ + Sbjct: 559 LNGVTTTTF--CGTPDYI-------------------APEILQELE-------------- 583 Query: 1236 TVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHL 1415 YG DWW+LG +MYEM+ G PPF +++ I++ + Sbjct: 584 -----------------YGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILH--DDV 624 Query: 1416 KFPEEAKLSSETKDLISKLLC-NVEQRLG----TKGAHEIKAHTWFRGVQWEKLYQ--MK 1574 +P LS E ++ + N +RLG G IK H +F+ + W L Q MK Sbjct: 625 LYP--VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKMK 682 Query: 1575 AAFVPEVNGELDTQNFEK 1628 F P + + D NF++ Sbjct: 683 PPFKPRIKTKRDVNNFDQ 700
>P68404:KPCB_MOUSE Protein kinase C beta type - Mus musculus (Mouse)| Length = 673 Score = 144 bits (362), Expect = 2e-33 Identities = 113/437 (25%), Positives = 195/437 (44%), Gaps = 9/437 (2%) Frame = +3 Query: 471 QDRKERRWMLERKL--QDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIG 644 + +E R ER Q + P E+ N + + R +M + DF L ++G Sbjct: 296 EGNEELRQKFERAKIGQGTKAPEEKTANTISKFDNNGN------RDRMKLTDFNFLMVLG 349 Query: 645 RGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA-YIVKLYYS 821 +G+FG+V L K + +YA+K LKK +++ VE E+ +LA ++ +L+ Sbjct: 350 KGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSC 409 Query: 822 FQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKP 1001 FQ + LY +MEY+ GGD+M + + E A FY AE + + + I+RD+K Sbjct: 410 FQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKL 469 Query: 1002 DNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRT 1181 DN FG+CK + + D + T P Sbjct: 470 DNVMLDSEGHIKIADFGMCK---------------------ENIWDGVTTKTFCGTP--- 505 Query: 1182 QQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFY 1361 DYIAPE++ + YG DWW+ G ++YEML G PF Sbjct: 506 -----------------------DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFE 542 Query: 1362 SEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-NVEQRL--GTKGAHEIKAHT 1532 ED + I+ ++ +P+ +S E + L+ + +RL G +G +IK H Sbjct: 543 GEDEDELFQSIM--EHNVAYPK--SMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHA 598 Query: 1533 WFRGVQWEKL--YQMKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKD- 1703 +FR + WEKL +++ + P+ G + +NF++F V + P ++++ + D Sbjct: 599 FFRYIDWEKLERKEIQPPYKPKACGR-NAENFDRFFTRHPPVLTP----PDQEVIRNIDQ 653 Query: 1704 ANFVGYTYKNFEIVNDD 1754 + F G+++ N E + + Sbjct: 654 SEFEGFSFVNSEFLKPE 670
>P05126:KPCB_BOVIN Protein kinase C beta type - Bos taurus (Bovine)| Length = 673 Score = 143 bits (360), Expect = 3e-33 Identities = 111/421 (26%), Positives = 190/421 (45%), Gaps = 10/421 (2%) Frame = +3 Query: 522 EVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVY 701 + P E+ N + + R +M + DF L ++G+G+FG+V L K + +Y Sbjct: 315 KTPEEKTTNTISKFDNNGN------RDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELY 368 Query: 702 AMKKLKKSEMLRRGQVEHVKAERNLLAEVDSA-YIVKLYYSFQDDEFLYLIMEYLPGGDM 878 A+K LKK +++ VE E+ +LA ++ +L+ FQ + LY +MEY+ GGD+ Sbjct: 369 AVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDL 428 Query: 879 MTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLC 1058 M + + E A FY AE + + + I+RD+K DN FG+C Sbjct: 429 MYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMC 488 Query: 1059 KPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYST 1238 K + + D + T P Sbjct: 489 K---------------------ENIWDGVTTKTFCGTP---------------------- 505 Query: 1239 VGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLK 1418 DYIAPE++ + YG DWW+ G ++YEML G PF ED + I+ ++ Sbjct: 506 ----DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIM--EHNVA 559 Query: 1419 FPEEAKLSSET----KDLISKLLCNVEQRL--GTKGAHEIKAHTWFRGVQWEKL--YQMK 1574 +P+ +S E K LI+K + +RL G +G +IK H +FR + WEKL +++ Sbjct: 560 YPK--SMSKEAVAICKGLITK---HPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQ 614 Query: 1575 AAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKD-ANFVGYTYKNFEIVND 1751 + P+ G + +NF++F V + P ++++ + D + F G+++ N E + Sbjct: 615 PPYKPKACGR-NAENFDRFFTRHPPVLTP----PDQEVIRNIDQSEFEGFSFVNSEFLKP 669 Query: 1752 D 1754 + Sbjct: 670 E 670
>P09215:KPCD_RAT Protein kinase C delta type - Rattus norvegicus (Rat)| Length = 673 Score = 142 bits (359), Expect = 4e-33 Identities = 108/380 (28%), Positives = 170/380 (44%), Gaps = 6/380 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEV- 788 +E+F ++G+G+FG+V L K +A+K LKK +L VE E+ +LA Sbjct: 344 LENFTFQKVLGKGSFGKVLLAELKGKERYFAIKYLKKDVVLIDDDVECTMVEKRVLALAW 403 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 ++ ++ L +FQ + L+ +ME+L GGD+M + K A FY AE + ++ +H Sbjct: 404 ENPFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLH 463 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 I+RD+K DN FG+CK Sbjct: 464 GKGIIYRDLKLDNVMLDKDGHIKIADFGMCKE---------------------------- 495 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 + + +NR A + GTPDYIAPE+L Y DWWS G ++ Sbjct: 496 ----------------NIFGENR---ASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLL 536 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTK 1505 YEML+G PF+ +D I H +P ++ E+KD++ KL + +RLG Sbjct: 537 YEMLIGQSPFHGDDEDELFESIRVDTPH--YPR--WITKESKDIMEKLFERDPAKRLGVT 592 Query: 1506 GAHEIKAHTWFRGVQWEKLYQMKA--AFVPEVNGELDTQNFE-KFEETGAQVQSSSKAGP 1676 G I+ H +F+ + W L + K F P+V D NF+ +F Q+ S K Sbjct: 593 G--NIRLHPFFKTINWNLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDK--- 647 Query: 1677 WRKMLPSKDAN-FVGYTYKN 1733 ++ S D F G+++ N Sbjct: 648 --NLIDSMDQTAFKGFSFVN 665
>P10830:KPCE_RABIT Protein kinase C epsilon type - Oryctolagus cuniculus (Rabbit)| Length = 736 Score = 142 bits (357), Expect = 7e-33 Identities = 99/358 (27%), Positives = 160/358 (44%), Gaps = 13/358 (3%) Frame = +3 Query: 594 QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN 773 Q ++G+++F + ++G+G+FG+V L K VYA+K LKK +L+ V+ E+ Sbjct: 398 QAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKR 457 Query: 774 LLAEVDS-AYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVL 950 +LA Y+ +LY FQ + L+ +MEY+ GGD+M + R E ++FY AE Sbjct: 458 ILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTS 517 Query: 951 AIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP-----LDSSNFPNLNEPDYTPG 1115 A+ +H+H I+RD+K DN FG+CK + ++ F PDY Sbjct: 518 ALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTF--CGTPDYI-- 573 Query: 1116 KGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGM 1295 AP+ Q+ + YG Sbjct: 574 -----------------APEILQELE-------------------------------YGP 585 Query: 1296 ECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL 1475 DWW+LG +MYEM+ G PPF +++ I++ + +P LS E ++ + Sbjct: 586 SVDWWALGVLMYEMMAGQPPFEADNEDDLFESILH--DDVLYP--VWLSKEAVSILKAFM 641 Query: 1476 C-NVEQRLG----TKGAHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFEK 1628 N +RLG G IK H +F+ + W L Q +K F P + + D NF++ Sbjct: 642 TKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQ 699
>P13677:KPC2_DROME Protein kinase C, eye isozyme - Drosophila melanogaster (Fruit fly)| Length = 700 Score = 142 bits (357), Expect = 7e-33 Identities = 106/421 (25%), Positives = 185/421 (43%), Gaps = 8/421 (1%) Frame = +3 Query: 507 KLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKT 686 +L+D EV + + N + ++ K+ + +R + DF + +IG+G+FG+V L + Sbjct: 334 RLRD-EVRHDRRPNEKRRMDNKDMPHNMSKRDMIRAADFNFVKVIGKGSFGKVLLAERRG 392 Query: 687 SRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA-EVDSAYIVKLYYSFQDDEFLYLIMEYL 863 + +YA+K L+K +++ +E E+ +LA ++V ++ FQ + L+ +MEY Sbjct: 393 TDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYC 452 Query: 864 PGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXX 1043 GGD+M + + E A FY E +A+ +H+ + I+RD+K DN Sbjct: 453 KGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLV 512 Query: 1044 XFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRM 1223 FGL K E ++ Q R Sbjct: 513 DFGLSK------------------------------------------EGVTERQTTR-- 528 Query: 1224 LAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNW 1403 + GTP+Y+APE++ Y + DWWS G +++E + G PF +D + R I + Sbjct: 529 ---TFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDK 585 Query: 1404 RSHLKFPEEAKLSSETKDLISKLLC---NVEQRLGTKGAHEIKAHTWFRGVQWEK--LYQ 1568 ++ FP+ S E D+I+ L N G EI H +FR V W+K + Sbjct: 586 KA--VFPKH--FSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACE 641 Query: 1569 MKAAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRK--MLPSKDANFVGYTYKNFEI 1742 M+ P + D NF+ A + + P K M+ +F+G+++ N E Sbjct: 642 MEPPIKPMIKHRKDISNFD-----DAFTKEKTDLTPTDKLFMMNLDQNDFIGFSFMNPEF 696 Query: 1743 V 1745 + Sbjct: 697 I 697
>P24583:KPC1_YEAST Protein kinase C-like 1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1151 Score = 141 bits (356), Expect = 9e-33 Identities = 104/420 (24%), Positives = 184/420 (43%), Gaps = 7/420 (1%) Frame = +3 Query: 516 DAEVPAEEQNNILKHLEKKETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRS 695 D + P + Q + +K+ + R K+ +++F LL ++G+G FG+V L + K + Sbjct: 794 DQQSPQKSQTSTSAKHKKRAAK-----RRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDR 848 Query: 696 VYAMKKLKKSEMLRRGQVEHVKAERN---LLAEVDSAYIVKLYYSFQDDEFLYLIMEYLP 866 + A+K LKK +++ +E +AE+ L + ++ LY SFQ + +Y ME++ Sbjct: 849 LCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIG 908 Query: 867 GGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXX 1046 GGD+M ++ L+ AKFY AE +LA++ H + I+RD+K +N Sbjct: 909 GGDLM-WHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIAD 967 Query: 1047 FGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRML 1226 +GLCK W NR Sbjct: 968 YGLCKD--------------------------------------------EMWYGNR--- 980 Query: 1227 AYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWR 1406 + GTP+++APE+L ++ Y DWW+ G ++Y+ML+ PF +D I+ Sbjct: 981 TSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDE 1040 Query: 1407 SHLKFPEEAKLSSETKDLISKLLCNVEQRLGT--KGAHEIKAHTWFRGVQWEKL--YQMK 1574 ++ + L++K + E+RLG + A E+ +FR + ++ + ++K Sbjct: 1041 PLYPIDMAGEIVQIFQGLLTK---DPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVK 1097 Query: 1575 AAFVPEVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDANFVGYTYKNFEIVNDD 1754 ++PE+ DT FE Q + A P LPS ++ F + DD Sbjct: 1098 PPYIPEIKSPEDTSYFE---------QEFTSAPPTLTPLPSVLTTSQQEEFRGFSFMPDD 1148
>Q03306:PKH3_YEAST Serine/threonine-protein kinase PKH3 - Saccharomyces cerevisiae| (Baker's yeast) Length = 898 Score = 141 bits (355), Expect = 1e-32 Identities = 94/327 (28%), Positives = 159/327 (48%), Gaps = 10/327 (3%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEV-RLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-- 773 K DF +G G++ V + +K+ +YA+K K +++ +V++V E+N Sbjct: 5 KRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTM 64 Query: 774 -LLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVL 950 LLA+ A I+KLYY+F D+E LY ++++ PGG++++LL + T + + + A+ + Sbjct: 65 NLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLID 124 Query: 951 AIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKP 1130 A+E IH H IHRD+KP+N FG +D P+L+ G AK Sbjct: 125 ALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATID----PSLS------GDSAKF 174 Query: 1131 LPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWW 1310 D+ N + S VGT +Y++PE+LL G D W Sbjct: 175 NSDSNGSKDNQNCA--------------------SFVGTAEYVSPELLLYNQCGYGSDIW 214 Query: 1311 SLGAIMYEMLVGYPPFYSEDPMSTCRKIV----NWRSHLKFPEE-AKLSSETKDLISKLL 1475 +LG ++Y+ + G PPF E+ + T KIV W + + + ++ +L+ K+L Sbjct: 215 ALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKIL 274 Query: 1476 -CNVEQRLGTKGAHEIKAHTWFRGVQW 1553 V +R+ + +IK H +F V W Sbjct: 275 VIEVNERISLE---QIKRHPYFSKVDW 298
>Q05999:KPK7_ARATH Putative serine/threonine-protein kinase PK7 - Arabidopsis thaliana| (Mouse-ear cress) Length = 578 Score = 140 bits (353), Expect = 2e-32 Identities = 116/437 (26%), Positives = 193/437 (44%), Gaps = 50/437 (11%) Frame = +3 Query: 393 SSATKQKVAAAKQYIENHYKTQMKSLQ-------DRKERRWMLERKLQDAEVPAEEQNNI 551 SS T AKQ N ++ S+ D ++ M+ R ++V E ++ Sbjct: 87 SSPTNTFYTEAKQSFTNTEFSECASISTIGIGGIDLEKNGVMIYRGSIGSDVSDESSSSG 146 Query: 552 LK------HLEKKETEYMRLQ--RHKMG----VEDFELLTIIGRGAFGEVRLCREKTSRS 695 L H + + ++ +Q R ++G +DF+L+ +G G G V L + Sbjct: 147 LSNAAYKPHRDNNDKRWVAIQEVRSRVGSSLEAKDFKLIKKLGGGDIGNVYLAELIGTGV 206 Query: 696 VYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGD 875 +A+K ++K+ + R ++ + E+ +L +D ++ LY F+ + L+ME+ PGGD Sbjct: 207 SFAVKVMEKAAIAARKKLVRAQTEKEILQSLDHPFLPTLYSHFETEMNSCLVMEFCPGGD 266 Query: 876 MMTL--LMRKDTLTEDEAKFYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXF 1049 + +L R E A+FY+AE +LA+E +H I+RD+KP+N F Sbjct: 267 LHSLRQKQRGKYFPEQAARFYVAEVLLAMEYLHMLGIIYRDLKPENVLVREDGHIMLSDF 326 Query: 1050 GL--------------CKPLDSSNFPNLNEPDYTPGKGAKPLPD------NTSRLTNPSA 1169 L L+S + +P PD T R + Sbjct: 327 DLSLRCAVSPTLVRFAAITLESKSSSYCIQPTCVDQSSCIVQPDCIQPVCFTPRFLSKGK 386 Query: 1170 PKRTQQEQLSHWQKNRRMLAYST-------VGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 ++ + + ++A T VGT +Y+APE++ +G+G DWW+ G + Sbjct: 387 HRKKSNDMSRQIRPLPELIAEPTSARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFL 446 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQ-RLG-T 1502 YE+L G PF D +T +V L+FPE +S +DLI LL Q RL Sbjct: 447 YELLFGITPFRGGDNRATLFNVVG--QPLRFPEHPNVSFAARDLIRGLLVKEPQHRLAYR 504 Query: 1503 KGAHEIKAHTWFRGVQW 1553 +GA EIK H +F+ V W Sbjct: 505 RGATEIKQHPFFQSVNW 521
>Q8SRK8:KAPC_ENCCU Probable cAMP-dependent protein kinase catalytic subunit -| Encephalitozoon cuniculi Length = 322 Score = 139 bits (351), Expect = 4e-32 Identities = 102/339 (30%), Positives = 158/339 (46%), Gaps = 5/339 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTS-RSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 ++DFE + ++G GAFG+V L R K+S SV+AMK L E+LR+ + ++ E ++L + Sbjct: 4 IQDFEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILKRI 63 Query: 789 DSA-YIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESI 965 ++ KLY + + LIMEY+ GG++ L + E A+FY AE + A+ I Sbjct: 64 YGCPFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRFI 123 Query: 966 HKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNT 1145 H ++RD+KP+N FG +S N Sbjct: 124 HGRGILYRDLKPENILITSTGHIKLIDFGF-SVYESENI--------------------- 161 Query: 1146 SRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAI 1325 Y GTP+Y++PE L + G D+W LG + Sbjct: 162 ----------------------------YMISGTPEYMSPEKLRSEDDGRASDYWGLGVM 193 Query: 1326 MYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGT 1502 +YEML G PPFY + KI+ S++ FP +S + LI+ LL N RLGT Sbjct: 194 IYEMLCGDPPFYDSSADAIYHKIL--ESNVVFPH--YVSPVARCLITGLLDKNRATRLGT 249 Query: 1503 KGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDT 1613 KG EI H +F+G+ W ++ +++ F+P N L + Sbjct: 250 KGICEIMGHPFFKGIDWHEVESRRIEPPFIPNPNTVLSS 288
>P34100:PKD1_DICDI Developmentally-regulated protein kinase 1 - Dictyostelium discoideum| (Slime mold) Length = 416 Score = 139 bits (350), Expect = 5e-32 Identities = 104/341 (30%), Positives = 145/341 (42%), Gaps = 5/341 (1%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVD 791 + DF +G G+FG +LCR + S + K L++ ++ EHV E N++ + Sbjct: 33 ISDFNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVHEKHKEHVNNEINIMLNIS 92 Query: 792 SAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIHK 971 YIVK Y +F ++ IMEY D+ L TE K +AE VLAIE +H Sbjct: 93 HPYIVKTYSTFNTPTKIHFIMEYAGKKDLFHHLRANKCFTEQTTKLIVAEIVLAIEYLHA 152 Query: 972 HNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTSR 1151 N I+RD+KP+N FG K GK NTS Sbjct: 153 ENIIYRDLKPENILIDEKGHIKLTDFGFSKKT-------------VGGK-------NTS- 191 Query: 1152 LTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVL-LKKGYGMECDWWSLGAIM 1328 S GT DY+APE+L G+G DWW+LG ++ Sbjct: 192 ---------------------------SVCGTFDYMAPEILNSSNGHGKPVDWWALGVVV 224 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRLGTK 1505 YE++ G PF + RK L F + + LS E KD I +LL + +RLGT Sbjct: 225 YELVTGKLPFSNSKESLLNRKA---DFQLIF-QNSYLSDEIKDFIFQLLSVDPSKRLGTF 280 Query: 1506 GAHEIKAHTWFRGVQW---EKLYQMKAAFVPEVNGELDTQN 1619 + I+ H WF + W E YQ ++G L T N Sbjct: 281 DSCSIRNHKWFSDINWLHLESKYQ--------IDGPLSTLN 313
>P13678:KPC3_DROME Protein kinase C - Drosophila melanogaster (Fruit fly)| Length = 634 Score = 139 bits (350), Expect = 5e-32 Identities = 96/351 (27%), Positives = 161/351 (45%), Gaps = 10/351 (2%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 K + DF + ++G+G+FG+V L +K + +YA+K LKK +++ V+ E+ +LA Sbjct: 297 KCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILA 356 Query: 783 -EVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 + ++ L+ FQ + L+ +MEY+ GGD+M + + A FY AE LA++ Sbjct: 357 LAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQ 416 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP-----LDSSNFPNLNEPDYTPGKGA 1124 +H H I+RD+K DN FG+CK + ++ F PDY Sbjct: 417 FLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTF--CGTPDYI----- 469 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 AP+ ++++ YG D Sbjct: 470 --------------APEILKEQE-------------------------------YGASVD 484 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WW+LG +MYEM+ G PPF +++ I++ + +P LS E ++ L N Sbjct: 485 WWALGVLMYEMMAGQPPFEADNEDELFDSIMH--DDVLYP--VWLSREAVSILKGFLTKN 540 Query: 1482 VEQRLGTKG-AHEIKAHTWFRGVQWEKLYQ--MKAAFVPEVNGELDTQNFE 1625 EQRLG G +EI+ H +F + W++L + +K F P++ D NF+ Sbjct: 541 PEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFD 591
>Q753D9:PKH3_ASHGO Serine/threonine-protein kinase PKH3 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 726 Score = 139 bits (349), Expect = 6e-32 Identities = 95/323 (29%), Positives = 148/323 (45%), Gaps = 6/323 (1%) Frame = +3 Query: 618 DFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN---LLAEV 788 DF +G G++ V E++S+ YA+K K ++ +V++V E+N LL + Sbjct: 9 DFLFREELGHGSYSTVYRVVERSSQHQYAIKICSKRHIIGENKVKYVTIEKNTLNLLGQA 68 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 + I+KLYY+F D E LY +M+ PGG+++ LL R+ +E A+ Y+ + V +E IH Sbjct: 69 NHPGIIKLYYTFHDQENLYFVMDLAPGGELLQLLRRQRVFSEAWARHYMCQLVDTVEYIH 128 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPDNTS 1148 IHRD+KP+N FG + S+ G KP Sbjct: 129 SMGVIHRDLKPENVLLDKEGRLMIADFGAAYTVGQSD---------AGSDGDKP------ 173 Query: 1149 RLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIM 1328 A S VGT +Y++PE+LL+ D W+LG ++ Sbjct: 174 --------------------------ATSFVGTAEYVSPELLLENKSYYSSDVWALGCML 207 Query: 1329 YEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNVEQRLGTKG 1508 Y+ L G PPF ++ M T +IVN + P + L+SK+L + T Sbjct: 208 YQFLQGTPPFRGQNEMETFEQIVNLDYTWRIPANPLAAG----LVSKILVLDPSQRYT-- 261 Query: 1509 AHEIKAHTWFRGVQW---EKLYQ 1568 +IK H WF GV W EK+++ Sbjct: 262 LEQIKKHKWFSGVDWNNKEKIWR 284
>Q9W0V1:PDPK1_DROME 3-phosphoinositide-dependent protein kinase 1 - Drosophila| melanogaster (Fruit fly) Length = 836 Score = 138 bits (348), Expect = 8e-32 Identities = 106/404 (26%), Positives = 184/404 (45%), Gaps = 24/404 (5%) Frame = +3 Query: 429 QYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEKKETEYMRLQRHKM 608 Q +N + Q + L +++ + Q + P ++Q + + ++ + ++ + Sbjct: 182 QQYQNDIRQQTEILDMLRQQHQQGYQSQQQQQQPQQQQEQQQQQEQSQQQQQLQNPAPRR 241 Query: 609 GVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLAEV 788 DF IG G++ V L + SR YA+K +K +LR + +++K ER ++ ++ Sbjct: 242 SPNDFIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMHQM 301 Query: 789 DSAY-IVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESI 965 + V L +FQD LY +M Y GDM+ + R + + Y AE +LA E + Sbjct: 302 TNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDVACTRHYAAELLLACEHM 361 Query: 966 HKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDS---------------SNFPNLNEP 1100 H+ N +HRD+KP+N FG K + + SN +E Sbjct: 362 HRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHERALATEHCSEQRRSNSDEDDED 421 Query: 1101 DYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAY---STVGTPDYIAPEV 1271 + D S + ++ Q+E S + RR + S VGT Y++PEV Sbjct: 422 SDRLENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRYNRHRKASFVGTAQYVSPEV 481 Query: 1272 LLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSET 1451 L D W+LG I+Y+M+ G PPF + ++I++ + FP+ + Sbjct: 482 LQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILD--CAVDFPQ--GFDKDA 537 Query: 1452 KDLISKLL-CNVEQRLGTK---GAHE-IKAHTWFRGVQWEKLYQ 1568 +DL+ KLL + RLG + G +E I+AH +F G+ W+ L Q Sbjct: 538 EDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAGIDWQTLRQ 581
>P23298:KPCL_MOUSE Protein kinase C eta type - Mus musculus (Mouse)| Length = 683 Score = 136 bits (342), Expect = 4e-31 Identities = 95/353 (26%), Positives = 163/353 (46%), Gaps = 12/353 (3%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 + G+++FE + ++G+G+FG+V L R K + +YA+K LKK +L+ VE E+ +L+ Sbjct: 349 RFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILS 408 Query: 783 EV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 + ++ +L+ FQ + L+ +ME++ GGD+M + + E A+FY AE + A+ Sbjct: 409 LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALM 468 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP-----LDSSNFPNLNEPDYTPGKGA 1124 +H+ I+RD+K DN FG+CK + ++ F PDY Sbjct: 469 FLHEKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATF--CGTPDYI----- 521 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 AP+ Q+ ML YG D Sbjct: 522 --------------APEILQE-----------ML--------------------YGPAVD 536 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLC-N 1481 WW++G ++YEML G+ PF +E+ I+N + +P L + + ++ + N Sbjct: 537 WWAMGVLLYEMLCGHAPFEAENEDDLFEAILN--DEVVYP--TWLHEDARGILKSFMTKN 592 Query: 1482 VEQRLGT---KGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFE 1625 RLG+ G HEI H +F+ + W +L Q++ F P + D NF+ Sbjct: 593 PTMRLGSLTQGGEHEILRHPFFKEIDWAQLNHRQLEPPFRPRIKSREDVSNFD 645
>Q6FV07:IPL1_CANGA Spindle assembly checkpoint kinase - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 358 Score = 135 bits (341), Expect = 5e-31 Identities = 93/313 (29%), Positives = 150/313 (47%), Gaps = 1/313 (0%) Frame = +3 Query: 600 HKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLL 779 +K+ ++DFE+ +G+G FG+V R K S + A+K ++K+E+L+ ++ +K E ++ Sbjct: 93 NKLSLKDFEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQ 152 Query: 780 AEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 +D I+KLY F D++ +YL+ME+ G++ L + A YI + A+ Sbjct: 153 LGMDHPNIIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALH 212 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYTPGKGAKPLPD 1139 +HK IHRD+KP+N F N+ + L D Sbjct: 213 YMHKKRIIHRDVKPENVLI--------------------GFDNVVK-----------LAD 241 Query: 1140 NTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLG 1319 + NP KR + GT DY++PE++ + Y + D W+LG Sbjct: 242 FGWSILNPEGSKRK-----------------TLCGTIDYLSPEMITPREYDEQVDVWALG 284 Query: 1320 AIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLL-CNVEQRL 1496 + YE++VG PPF T ++I+ + L FPE +S + KDLISKLL + QRL Sbjct: 285 VLAYELVVGVPPFEENSKELTYKRIL--KCDLNFPE--SISKDAKDLISKLLVTDTTQRL 340 Query: 1497 GTKGAHEIKAHTW 1535 G +K H W Sbjct: 341 SLTG---VKTHPW 350
>Q64617:KPCL_RAT Protein kinase C eta type - Rattus norvegicus (Rat)| Length = 683 Score = 135 bits (339), Expect = 9e-31 Identities = 97/352 (27%), Positives = 161/352 (45%), Gaps = 11/352 (3%) Frame = +3 Query: 603 KMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLLA 782 + G+++FE + ++G+G+FG+V L R K + +YA+K LKK +L+ VE E+ +L+ Sbjct: 349 RFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILS 408 Query: 783 EV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIE 959 + ++ +L+ FQ + L+ +ME++ GGD+M + + E A+FY AE + A+ Sbjct: 409 LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALM 468 Query: 960 SIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP-----LDSSNFPNLNEPDYTPGKGA 1124 +H+ I+RD+K DN FG+CK + ++ F PDY Sbjct: 469 FLHEKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATF--CGTPDYI----- 521 Query: 1125 KPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECD 1304 AP+ Q+ ML YG D Sbjct: 522 --------------APEILQE-----------ML--------------------YGPAVD 536 Query: 1305 WWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCNV 1484 WW++G ++YEML G+ PF +E+ I+N + +P T L S + N Sbjct: 537 WWAMGVLLYEMLCGHAPFEAENEDDLFEAILN--DEVVYPTWLH-EDATGILKSFMTKNP 593 Query: 1485 EQRLGT---KGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFE 1625 RLG+ G HEI H +F+ + W +L Q++ F P + D NF+ Sbjct: 594 TMRLGSLTQGGEHEILRHPFFKEIDWVQLNHRQLEPPFRPRIKSREDVSNFD 645
>Q9LSF1:OXI1_ARATH Serine/threonine-protein kinase OXI1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 421 Score = 134 bits (338), Expect = 1e-30 Identities = 107/372 (28%), Positives = 176/372 (47%), Gaps = 30/372 (8%) Frame = +3 Query: 594 QRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVY-------AMKKLKKSEMLRRGQVE 752 Q + E+L+++GRGA G V L R+ ++ + A++K KK + + Sbjct: 8 QSRALDFNRLEVLSLLGRGAKGVVFLVRDDDAKLLALKVILKEAIEKKKKGRESEDDEYK 67 Query: 753 HVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLL-MRKDTLTEDEA-K 926 V E+ +L+ D L+ D+ + ++Y PG ++ +L M+ +++ DE + Sbjct: 68 RVSFEQGVLSRFDHPLFPSLHGVLATDKVIGYAIDYCPGQNLNSLRKMQSESMFSDEIIR 127 Query: 927 FYIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCK---PLDSSNFPNLNE 1097 FY AE VLA++ +H ++RD+KPDN F L P P+L++ Sbjct: 128 FYAAELVLALDYLHNQGIVYRDLKPDNVMIQENGHLMLIDFDLSTNLAPRTPQPSPSLSK 187 Query: 1098 PDYTPGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYST-------VGTPDY 1256 P T K K L TS + +P QE +S + ++ S+ VGT +Y Sbjct: 188 PSPTM-KRKKRLFRFTSFCNSGISP----QESISVHSSSTLAVSDSSGEKSNSFVGTEEY 242 Query: 1257 IAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAK 1436 +APEV+ G+ DWWSLG ++YEML G PF + T +I++ K P Sbjct: 243 VAPEVISGDGHDFAVDWWSLGVVLYEMLYGATPFRGSNRKETFYRILS-----KPPNLTG 297 Query: 1437 LSSETKDLISKLLCNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQM-KAAFVP-------- 1589 ++ +DLI +LL R EIK H +FRGV WEK+ + + ++P Sbjct: 298 ETTSLRDLIRRLLEKDPSR--RINVEEIKGHDFFRGVDWEKVILVSRPPYIPAPDDGGDK 355 Query: 1590 --EVNGELDTQN 1619 +VN ++D +N Sbjct: 356 GTDVNTKMDVEN 367
>Q6DE08:AUKBA_XENLA Serine/threonine-protein kinase 12-A - Xenopus laevis (African clawed| frog) Length = 361 Score = 134 bits (338), Expect = 1e-30 Identities = 107/385 (27%), Positives = 167/385 (43%), Gaps = 1/385 (0%) Frame = +3 Query: 390 PSSATKQKVAAAKQYIENHYKTQMKSLQDRKERRWMLERKLQDAEVPAEEQNNILKHLEK 569 PSSAT + K+ + + T +L +R L R A + + + Sbjct: 19 PSSATAAQRVLRKEPYVSTFTTPSDNLL---AQRTQLSRITPSASSSVPGRVAVSTEMPS 75 Query: 570 KETEYMRLQRHKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQV 749 + T + + K ++DF++ +G+G FG V L REK ++ + A+K L KS++ + G Sbjct: 76 QNTALAEMPKRKFTIDDFDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVE 135 Query: 750 EHVKAERNLLAEVDSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKF 929 ++ E + + + I+++Y F D + +YL++E+ P G++ L + E + Sbjct: 136 HQLRREIEIQSHLRHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSAT 195 Query: 930 YIAETVLAIESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKPLDSSNFPNLNEPDYT 1109 ++ E A+ H+ IHRDIKP+N Sbjct: 196 FMEELADALHYCHERKVIHRDIKPENLLMGY----------------------------- 226 Query: 1110 PGKGAKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGY 1289 KG + D + PS +RT GT DY+ PE++ K + Sbjct: 227 --KGELKIADFGWSVHAPSLRRRTM------------------CGTLDYLPPEMIEGKTH 266 Query: 1290 GMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISK 1469 + D W G + YE LVG PPF S T R+IVN LKFP LS +KDLISK Sbjct: 267 DEKVDLWCAGVLCYEFLVGMPPFDSPSHTETHRRIVN--VDLKFP--PFLSDGSKDLISK 322 Query: 1470 LL-CNVEQRLGTKGAHEIKAHTWFR 1541 LL + QRL KG E H W + Sbjct: 323 LLRYHPPQRLPLKGVME---HPWVK 344
>Q8TFG6:PPK18_SCHPO Serine/threonine-protein kinase ppk18 - Schizosaccharomyces pombe| (Fission yeast) Length = 1316 Score = 133 bits (334), Expect = 3e-30 Identities = 66/149 (44%), Positives = 97/149 (65%), Gaps = 1/149 (0%) Frame = +3 Query: 612 VEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERN-LLAEV 788 ++D+E++ I +G FG V L R+ T+ +YA+K L+K +M+ + QV +VKAER L+A+ Sbjct: 561 IQDYEIIKPISKGTFGTVYLSRKNTTGEIYAIKVLRKVDMISKNQVANVKAERAVLMAQE 620 Query: 789 DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAIESIH 968 +SA++ KLYY+FQ ++LYL+ME++ GGD +LL T+ E AK YIAE L +E +H Sbjct: 621 ESAFVAKLYYAFQSRDYLYLVMEFMNGGDCASLLKSLYTIPESWAKIYIAEVALGLEHLH 680 Query: 969 KHNYIHRDIKPDNXXXXXXXXXXXXXFGL 1055 + IHRDIKPDN FGL Sbjct: 681 RLGIIHRDIKPDNILMSITGHLKLADFGL 709 Score = 102 bits (253), Expect = 8e-21 Identities = 59/160 (36%), Positives = 85/160 (53%), Gaps = 3/160 (1%) Frame = +3 Query: 1239 VGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLK 1418 VGTPDY+APE L DWW+LG +++E L GYPPF++E P I+ +++ Sbjct: 832 VGTPDYLAPETLRGSTQDDMVDWWALGCVLFEFLFGYPPFHAETPEKVFENIL--ANNIA 889 Query: 1419 FP--EEAKLSSETKDLISKLL-CNVEQRLGTKGAHEIKAHTWFRGVQWEKLYQMKAAFVP 1589 +P E S E DLI+ L N E+RLG +EIK H +F G+ W+ ++ +A F+P Sbjct: 890 WPDLEMYPCSEEALDLINGFLQPNPERRLGFSDINEIKEHPFFNGINWDDIFSHEAPFIP 949 Query: 1590 EVNGELDTQNFEKFEETGAQVQSSSKAGPWRKMLPSKDAN 1709 LDT F+ A+ SS ++ SKD N Sbjct: 950 APETPLDTAYFDSRGAGAAESNMSSSVNSGEEV--SKDNN 987
>P24723:KPCL_HUMAN Protein kinase C eta type - Homo sapiens (Human)| Length = 682 Score = 132 bits (332), Expect = 6e-30 Identities = 96/353 (27%), Positives = 160/353 (45%), Gaps = 11/353 (3%) Frame = +3 Query: 600 HKMGVEDFELLTIIGRGAFGEVRLCREKTSRSVYAMKKLKKSEMLRRGQVEHVKAERNLL 779 +++G+++FE + ++G+G+FG+V L R K + +YA+K LKK +L VE E+ +L Sbjct: 347 NRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRIL 406 Query: 780 AEV-DSAYIVKLYYSFQDDEFLYLIMEYLPGGDMMTLLMRKDTLTEDEAKFYIAETVLAI 956 + + ++ +L+ FQ + L+ +ME++ GGD+M + + E A+FY AE + A+ Sbjct: 407 SLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISAL 466 Query: 957 ESIHKHNYIHRDIKPDNXXXXXXXXXXXXXFGLCKP-----LDSSNFPNLNEPDYTPGKG 1121 +H I+RD+K DN FG+CK + ++ F PDY Sbjct: 467 MFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATF--CGTPDYI---- 520 Query: 1122 AKPLPDNTSRLTNPSAPKRTQQEQLSHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMEC 1301 AP+ Q+ ML YG Sbjct: 521 ---------------APEILQE-----------ML--------------------YGPAV 534 Query: 1302 DWWSLGAIMYEMLVGYPPFYSEDPMSTCRKIVNWRSHLKFPEEAKLSSETKDLISKLLCN 1481 DWW++G ++YEML G+ PF +E+ I+N + +P T L S + N Sbjct: 535 DWWAMGVLLYEMLCGHAPFEAENEDDLFEAILN--DEVVYPTWLH-EDATGILKSFMTKN 591 Query: 1482 VEQRLGT---KGAHEIKAHTWFRGVQWEKL--YQMKAAFVPEVNGELDTQNFE 1625 RLG+ G H I H +F+ + W +L Q++ F P + D NF+ Sbjct: 592 PTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFD 644 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 379,014,162 Number of extensions: 8514091 Number of successful extensions: 32747 Number of sequences better than 10.0: 2149 Number of HSP's gapped: 30705 Number of HSP's successfully gapped: 3417 Length of query: 700 Length of database: 100,686,439 Length adjustment: 120 Effective length of query: 580 Effective length of database: 67,771,039 Effective search space: 39307202620 Effective search space used: 39307202620 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
