ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf17n09 |
|---|---|
| Clone Library Name | barley_pub |
>Q6X4A2:CIPK1_ORYSJ CIPK-like protein 1 - Oryza sativa subsp. japonica (Rice)| Length = 449 Score = 563 bits (1452), Expect = e-160 Identities = 272/422 (64%), Positives = 340/422 (80%), Gaps = 1/422 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YELG+TIGEG+FAKV+ AK+T N AIK+LD+ V +H++VEQI+REI TMKL++HPN Sbjct: 20 YELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHPN 79 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 VV+L EVM SK++I++VLE+V GGELF+ I +G+L E+EAR+YF QLINAVDYCHSRGV Sbjct: 80 VVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRGV 139 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 YHRDLK ENLLLD+ G LKVSDFGLSA + Q K DGLLHT CGTPNYVAPEV+ D+GYDG Sbjct: 140 YHRDLKLENLLLDASGNLKVSDFGLSALTEQVKADGLLHTTCGTPNYVAPEVIEDRGYDG 199 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 AAD+WSCG+IL+VL+AG+LPF+D N++ LYK IS A +CP WFSTGA+ LI RILDPN Sbjct: 200 AAADIWSCGVILYVLLAGFLPFEDDNIIALYKKISEAQFTCPSWFSTGAKKLITRILDPN 259 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAF-DSSEEHLVAERREKPESMN 1090 P TRITI+QILED WFKK YKPP+ + + S +DVDAAF DS + H+ E ++P SMN Sbjct: 260 PTTRITISQILEDPWFKKGYKPPVFDEKYETSFDDVDAAFGDSEDRHVKEETEDQPTSMN 319 Query: 1091 AFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEEACGPLGFNVRKQNY 1270 AF LIS + NL NLFE + KRET F SQ P+EI++KIEEA PLGF+++K+NY Sbjct: 320 AFELISLNQALNLDNLFEAKK--EYKRETRFTSQCPPKEIITKIEEAAKPLGFDIQKKNY 377 Query: 1271 KMKLKGDKTGRKGHLSVATEVFEVAPSLHMVELRKTGGDTLEFHSFYQNFSSELKDIVWK 1450 KM+++ K GRKG+L+VATEVF+VAPSLH+VEL+K GDTLEF FY+ S++LKD+VWK Sbjct: 378 KMRMENLKAGRKGNLNVATEVFQVAPSLHVVELKKAKGDTLEFQKFYRTLSTQLKDVVWK 437 Query: 1451 TE 1456 + Sbjct: 438 CD 439
>Q9LDI3:CPK24_ARATH CBL-interacting serine/threonine-protein kinase 24 - Arabidopsis| thaliana (Mouse-ear cress) Length = 446 Score = 470 bits (1209), Expect = e-131 Identities = 230/423 (54%), Positives = 312/423 (73%), Gaps = 4/423 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+G+TIGEG+FAKVK A++T G AIK++ ++ +L+++MV+QIKREI+ MK++RHPN Sbjct: 11 YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPN 70 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L+EV+AS SKIY+VLEFV GGELFD+IV+ G+L E E+R+YF QL++AV +CH +GV Sbjct: 71 IVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGV 130 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 YHRDLKPENLLLD+ G LKVSDFGLSA + + LL T CGTPNYVAPEVL+ +GYDG Sbjct: 131 YHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVE--LLRTTCGTPNYVAPEVLSGQGYDG 188 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 AAD+WSCG+ILFV++AGYLPF + +L LY+ I+ A SCPPWFS + LI RILDPN Sbjct: 189 SAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPN 248 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREK----PE 1081 P TRI I I +D WF+ +Y P + E+V+L+D+ A FD E VAE E+ P Sbjct: 249 PKTRIQIQGIKKDPWFRLNYVPIRAREEEEVNLDDIRAVFDGIEGSYVAENVERNDEGPL 308 Query: 1082 SMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEEACGPLGFNVRK 1261 MNAF +I+ S G NL LF++ VKR+T F S+R P EI++ IE +GF Sbjct: 309 MMNAFEMITLSQGLNLSALFDRR-QDFVKRQTRFVSRREPSEIIANIEAVANSMGFKSHT 367 Query: 1262 QNYKMKLKGDKTGRKGHLSVATEVFEVAPSLHMVELRKTGGDTLEFHSFYQNFSSELKDI 1441 +N+K +L+G + + G L+V E++EVAPSL MV++RK G+TLE+H FY+ S+L++I Sbjct: 368 RNFKTRLEGLSSIKAGQLAVVIEIYEVAPSLFMVDVRKAAGETLEYHKFYKKLCSKLENI 427 Query: 1442 VWK 1450 +W+ Sbjct: 428 IWR 430
>P92937:CPK15_ARATH CBL-interacting serine/threonine-protein kinase 15 - Arabidopsis| thaliana (Mouse-ear cress) Length = 421 Score = 422 bits (1084), Expect = e-117 Identities = 216/402 (53%), Positives = 284/402 (70%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+GK +G+G+FAKV A+ + G + AIKV+D+ +L+ M EQIKREI+ M+L+RHPN Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRHPN 71 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LHEVMA+KSKIY V+E V+GGELF+K V++GKL ED AR+YF QL+ AVD+CHSRGV Sbjct: 72 IVELHEVMATKSKIYFVMEHVKGGELFNK-VSTGKLREDVARKYFQQLVRAVDFCHSRGV 130 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD +G LK+SDFGLSA S + DGLLHT CGTP YVAPEV++ GYDG Sbjct: 131 CHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDG 190 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 ADVWSCG+ILFVL+AGYLPF D NLM LYK I +A V P W + GA+ L+KRILDPN Sbjct: 191 FKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGAKRLLKRILDPN 250 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREKPESMNA 1093 P+TR++ +I++ WF+K + + E E+ + D +A ++S E + +++ ++NA Sbjct: 251 PNTRVSTEKIMKSSWFRKGLQEEVKESVEEETEVDAEAEGNASAE----KEKKRCINLNA 306 Query: 1094 FALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEEACGPLGFNVRKQNYK 1273 F +IS S GF+L LFEK G K E F S R EI K+ E L VRK+ ++ Sbjct: 307 FEIISLSTGFDLSGLFEK---GEEKEEMRFTSNREASEITEKLVEIGKDLKMKVRKKEHE 363 Query: 1274 MKLKGDKTGRKGHLSVATEVFEVAPSLHMVELRKTGGDTLEF 1399 ++K V EVFE+APS HMV L+K+GGDT E+ Sbjct: 364 WRVKMSAEA----TVVEAEVFEIAPSYHMVVLKKSGGDTAEY 401
>Q8RWC9:CIPK1_ARATH CBL-interacting serine/threonine-protein kinase 1 - Arabidopsis| thaliana (Mouse-ear cress) Length = 444 Score = 414 bits (1065), Expect = e-115 Identities = 206/422 (48%), Positives = 297/422 (70%), Gaps = 6/422 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YELG+T+GEG+F KVK AKDT +G + A+K++D++ + QIKREI T+K+++HP+ Sbjct: 20 YELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHPH 79 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LHEV+ASK+KI MV+E V GGELFD+IV++GKL E + R+ F QLI+ + YCHS+GV Sbjct: 80 IVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKGV 139 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +HRDLK EN+LLD+ G +K++DFGLSA +DDGLLHT CG+PNYVAPEVLA++GYDG Sbjct: 140 FHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYDG 199 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A+D+WSCG+IL+V++ G LPFDD NL LY+ I + + P W S GAR +IKR+LDPN Sbjct: 200 AASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGARTMIKRMLDPN 259 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFD----SSEEHLVAERREKPE 1081 P TRIT+ I EWFK +Y P + + +++ ++ D AF SEE + + P Sbjct: 260 PVTRITVVGIKASEWFKLEYIPSIPDDDDEEEVDTDDDAFSIQELGSEE---GKGSDSPT 316 Query: 1082 SMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEEACGPLGFNVRK 1261 +NAF LI S+ +L FE+E + +R F S + ++++ KIE A +GF+V+K Sbjct: 317 IINAFQLIGMSSFLDLSGFFEQE--NVSERRIRFTSNSSAKDLLEKIETAVTEMGFSVQK 374 Query: 1262 QNYKMKLKGDKTGRKGH--LSVATEVFEVAPSLHMVELRKTGGDTLEFHSFYQNFSSELK 1435 ++ K+++K ++ +KG LSV EVFE+ PSL++VELRK+ GD+ + Y+ LK Sbjct: 375 KHAKLRVKQEERNQKGQVGLSVTAEVFEIKPSLNVVELRKSYGDSCLYRQLYERL---LK 431 Query: 1436 DI 1441 D+ Sbjct: 432 DV 433
>O22932:CPK11_ARATH CBL-interacting serine/threonine-protein kinase 11 - Arabidopsis| thaliana (Mouse-ear cress) Length = 435 Score = 360 bits (923), Expect = 1e-98 Identities = 191/405 (47%), Positives = 263/405 (64%), Gaps = 7/405 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHK-MVEQIKREIATMKLIRHP 370 YELGK +G G+FAKV A+D R G + A+K+L++ +L + + IKREI+ M+ + HP Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHP 80 Query: 371 NVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 N+V+LHEVMA+KSKI+ +EFV+GGELF+KI G+L ED +RRYF QLI+AV YCH+RG Sbjct: 81 NIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARG 140 Query: 551 VYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYD 730 VYHRDLKPENLL+D G LKVSDFGLSA + Q + DGLLHT CGTP YVAPE+L+ KGY+ Sbjct: 141 VYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE 200 Query: 731 GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDP 910 G DVWSCGI+LFVL+AGYLPF+DPN+M +YK I + P W S + + R+LD Sbjct: 201 GAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDI 260 Query: 911 NPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREKPESMN 1090 NP TRITI +IL+D WF + + H++++ E+ V E +S+N Sbjct: 261 NPETRITIDEILKDPWFVRGGFKQIKFHDDEI------------EDQKVESSLEAVKSLN 308 Query: 1091 AFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEEACGPLGFNVRKQNY 1270 AF LIS S+G +L LF + E F S+++P+ + ++E GF R++N Sbjct: 309 AFDLISYSSGLDLSGLFAGCSNSSGESE-RFLSEKSPEMLAEEVE------GF-AREENL 360 Query: 1271 KMKLKGDK------TGRKGHLSVATEVFEVAPSLHMVELRKTGGD 1387 +MK K ++ G+ G + + + L +VE R+ GGD Sbjct: 361 RMKKKKEEEYGFEMEGQNGKFGIGICISRLNDLLVVVEARRRGGD 405
>O94168:SNF1_CANTR Carbon catabolite derepressing protein kinase - Candida tropicalis| (Yeast) Length = 619 Score = 259 bits (663), Expect = 2e-68 Identities = 128/259 (49%), Positives = 182/259 (70%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ KT+GEGSF KVK+A+ G A+K+++R + + M +++REI+ ++L+RHP+ Sbjct: 52 YQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPH 111 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+ SK +I MV+EF G ELFD IV GK+ EDEARR+F Q+I AV+YCH + Sbjct: 112 IIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHKI 170 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD +K++DFGLS D L T+CG+PNY APEV++ K Y G Sbjct: 171 VHRDLKPENLLLDDQLNVKIADFGLSNIMT---DGNFLKTSCGSPNYAAPEVISGKLYAG 227 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+IL+V++ G LPFDD + L+K IS + P + S GA++L+ R+L N Sbjct: 228 PEVDVWSSGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSPGAKHLLTRMLVVN 287 Query: 914 PHTRITIAQILEDEWFKKD 970 P RITI +I+EDEWFK+D Sbjct: 288 PLNRITIHEIMEDEWFKQD 306
>P06782:SNF1_YEAST Carbon catabolite derepressing protein kinase - Saccharomyces| cerevisiae (Baker's yeast) Length = 633 Score = 259 bits (661), Expect = 4e-68 Identities = 133/288 (46%), Positives = 193/288 (67%), Gaps = 5/288 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ KT+GEGSF KVK+A T G A+K++++ + + M +I+REI+ ++L+RHP+ Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 114 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+ SK +I MV+E+ G ELFD IV K+ E EARR+F Q+I+AV+YCH + Sbjct: 115 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKI 173 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD + +K++DFGLS D L T+CG+PNY APEV++ K Y G Sbjct: 174 VHRDLKPENLLLDEHLNVKIADFGLSNIMT---DGNFLKTSCGSPNYAAPEVISGKLYAG 230 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWSCG+IL+V++ LPFDD ++ L+K IS + P + S GA LIKR+L N Sbjct: 231 PEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVN 290 Query: 914 PHTRITIAQILEDEWFKKD-----YKPPLSEHNEDVSLEDVDAAFDSS 1042 P RI+I +I++D+WFK D P L H E+ + E+ D+ D S Sbjct: 291 PLNRISIHEIMQDDWFKVDLPEYLLPPDLKPHPEEEN-ENNDSKKDGS 337
>Q38997:KIN10_ARATH SNF1-related protein kinase catalytic subunit alpha KIN10 -| Arabidopsis thaliana (Mouse-ear cress) Length = 535 Score = 259 bits (661), Expect = 4e-68 Identities = 138/339 (40%), Positives = 208/339 (61%), Gaps = 17/339 (5%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+LG+T+G GSF +VK+A+ G AIK+L+R + +M E+++REI ++L HP+ Sbjct: 42 YKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 101 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+EV+ + + IY+V+E+V GELFD IV G+L EDEAR +F Q+I+ V+YCH V Sbjct: 102 IIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMV 161 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLDS +K++DFGLS +D L T+CG+PNY APEV++ K Y G Sbjct: 162 VHRDLKPENLLLDSKCNVKIADFGLSNI---MRDGHFLKTSCGSPNYAAPEVISGKLYAG 218 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWSCG+IL+ L+ G LPFDD N+ L+K I + P S GAR+LI R+L + Sbjct: 219 PEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVD 278 Query: 914 PHTRITIAQILEDEWFK-----------KDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVA 1060 P R+TI +I + WF+ D + +E++ E ++ FD HL+ Sbjct: 279 PMKRVTIPEIRQHPWFQAHLPRYLAVPPPDTVQQAKKIDEEILQEVINMGFD--RNHLIE 336 Query: 1061 ERREKPE---SMNAFALIS---RSAGFNLGNLFEKEMMG 1159 R + + ++ + ++ R++ LG F++ M G Sbjct: 337 SLRNRTQNDGTVTYYLILDNRFRASSGYLGAEFQETMEG 375
>P92958:KIN11_ARATH SNF1-related protein kinase catalytic subunit alpha KIN11 -| Arabidopsis thaliana (Mouse-ear cress) Length = 512 Score = 258 bits (658), Expect = 8e-68 Identities = 134/295 (45%), Positives = 190/295 (64%), Gaps = 11/295 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+LGKT+G GSF KVK+A+ G AIK+L+R + +M E+++REI ++L HP+ Sbjct: 20 YKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 79 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ +EV+ + S IY+V+E+V+ GELFD IV G+L EDEAR +F Q+I+ V+YCH V Sbjct: 80 IIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMV 139 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLDS +K++DFGLS +D L T+CG+PNY APEV++ K Y G Sbjct: 140 VHRDLKPENLLLDSRCNIKIADFGLSNV---MRDGHFLKTSCGSPNYAAPEVISGKLYAG 196 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWSCG+IL+ L+ G LPFDD N+ L+K I + P S+ AR+LI R+L + Sbjct: 197 PEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVD 256 Query: 914 PHTRITIAQILEDEWFKKD------YKPP-----LSEHNEDVSLEDVDAAFDSSE 1045 P RITI +I + WF+ PP + NE++ E V+ FD ++ Sbjct: 257 PVKRITIPEIRQHRWFQTHLPRYLAVSPPDTVEQAKKINEEIVQEVVNMGFDRNQ 311
>Q00372:SNF1_CANGA Carbon catabolite derepressing protein kinase - Candida glabrata| (Yeast) (Torulopsis glabrata) Length = 612 Score = 256 bits (654), Expect = 2e-67 Identities = 125/259 (48%), Positives = 181/259 (69%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ KT+GEGSF KVK+A G A+K++++ + + M +I+REI+ ++L+RHP+ Sbjct: 39 YQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 98 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+ SK +I MV+E+ G ELFD IV K+ E EARR+F Q+I+AV+YCH + Sbjct: 99 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVEYCHRHKI 157 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD + +K++DFGLS D L T+CG+PNY APEV++ K Y G Sbjct: 158 VHRDLKPENLLLDEHLNVKIADFGLSNIMT---DGNFLKTSCGSPNYAAPEVISGKLYAG 214 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWSCG+IL+V++ LPFDD ++ L+K IS + P + S GA +LIKR+L N Sbjct: 215 PEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGASDLIKRMLIVN 274 Query: 914 PHTRITIAQILEDEWFKKD 970 P RI+I +I++DEWFK D Sbjct: 275 PLNRISIHEIMQDEWFKVD 293
>P52497:SNF1_CANAL Carbon catabolite derepressing protein kinase - Candida albicans| (Yeast) Length = 620 Score = 255 bits (652), Expect = 4e-67 Identities = 133/282 (47%), Positives = 192/282 (68%), Gaps = 5/282 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ KT+GEGSF KVK+A+ G A+K+++R + + M +++REI+ ++L+RHP+ Sbjct: 53 YQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPH 112 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+ SK +I MV+EF G ELFD IV GK+ EDEARR+F Q+I AV+YCH + Sbjct: 113 IIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHKI 171 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYV-APEVLADKGYD 730 HRDLKPENLLLD +K++DFGLS D L T+CG+PNY+ APEV++ K Y Sbjct: 172 VHRDLKPENLLLDDQLNVKIADFGLSNIMT---DGNFLKTSCGSPNYMPAPEVISGKLYA 228 Query: 731 GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDP 910 G DVWS G+IL+V++ G LPFDD + L+K IS + P + S GA++L+ R+L Sbjct: 229 GPEVDVWSAGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSAGAKHLLTRMLVV 288 Query: 911 NPHTRITIAQILEDEWFKKDYK----PPLSEHNEDVSLEDVD 1024 NP RITI +I+ED+WFK+D PP N++ + DVD Sbjct: 289 NPLNRITIHEIMEDDWFKQDMPDYLLPPDLSKNKNSKI-DVD 329
>P54645:AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Rattus| norvegicus (Rat) Length = 548 Score = 249 bits (635), Expect = 4e-65 Identities = 128/297 (43%), Positives = 188/297 (63%), Gaps = 8/297 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LG T+G G+F KVKV K G A+K+L+R + +V +I+REI +KL RHP+ Sbjct: 16 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 75 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+++ S I+MV+E+V GGELFD I +G+L E E+RR F Q+++ VDYCH V Sbjct: 76 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 135 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPEN+LLD++ K++DFGL S D L T+CG+PNY APEV++ + Y G Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G+IL+ L+ G LPFDD ++ TL+K I P + + +L+K +L + Sbjct: 193 PEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVD 252 Query: 914 PHTRITIAQILEDEWFKKDYKPPL--------SEHNEDVSLEDVDAAFDSSEEHLVA 1060 P R TI I E EWFK+D L S +D +L++V F+ SEE +++ Sbjct: 253 PMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLS 309
>Q5RDH5:AAPK1_PONPY 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Pongo| pygmaeus (Orangutan) Length = 550 Score = 249 bits (635), Expect = 4e-65 Identities = 128/297 (43%), Positives = 188/297 (63%), Gaps = 8/297 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LG T+G G+F KVKV K G A+K+L+R + +V +I+REI +KL RHP+ Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 77 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+++ S I+MV+E+V GGELFD I +G+L E E+RR F Q+++ VDYCH V Sbjct: 78 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 137 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPEN+LLD++ K++DFGL S D L T+CG+PNY APEV++ + Y G Sbjct: 138 VHRDLKPENVLLDAHMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 194 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G+IL+ L+ G LPFDD ++ TL+K I P + + +L+K +L + Sbjct: 195 PEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVD 254 Query: 914 PHTRITIAQILEDEWFKKDYKPPL--------SEHNEDVSLEDVDAAFDSSEEHLVA 1060 P R TI I E EWFK+D L S +D +L++V F+ SEE +++ Sbjct: 255 PMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLS 311
>Q13131:AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Homo| sapiens (Human) Length = 550 Score = 249 bits (635), Expect = 4e-65 Identities = 128/297 (43%), Positives = 188/297 (63%), Gaps = 8/297 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LG T+G G+F KVKV K G A+K+L+R + +V +I+REI +KL RHP+ Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 77 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+++ S I+MV+E+V GGELFD I +G+L E E+RR F Q+++ VDYCH V Sbjct: 78 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 137 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPEN+LLD++ K++DFGL S D L T+CG+PNY APEV++ + Y G Sbjct: 138 VHRDLKPENVLLDAHMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 194 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G+IL+ L+ G LPFDD ++ TL+K I P + + +L+K +L + Sbjct: 195 PEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVD 254 Query: 914 PHTRITIAQILEDEWFKKDYKPPL--------SEHNEDVSLEDVDAAFDSSEEHLVA 1060 P R TI I E EWFK+D L S +D +L++V F+ SEE +++ Sbjct: 255 PMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLS 311
>Q5EG47:AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-1 - Mus| musculus (Mouse) Length = 548 Score = 247 bits (630), Expect = 1e-64 Identities = 127/297 (42%), Positives = 187/297 (62%), Gaps = 8/297 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LG T+G G+F KVKV K G A+K+L+R + +V +I+REI +KL RHP+ Sbjct: 16 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 75 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+++ S I+MV+E+V GGELFD I +G+L E E+RR F Q+++ VDYCH V Sbjct: 76 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 135 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPEN+LLD++ K++DFGL S D L T+CG+PNY APEV++ + Y G Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G+IL+ L+ G LPFDD ++ TL+K I P + + +L+K +L + Sbjct: 193 PEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVD 252 Query: 914 PHTRITIAQILEDEWFKKDYKPPL--------SEHNEDVSLEDVDAAFDSSEEHLVA 1060 P R I I E EWFK+D L S +D +L++V F+ SEE +++ Sbjct: 253 PMKRAAIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLS 309
>Q5RD00:AAPK2_PONPY 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Pongo| pygmaeus (Orangutan) Length = 552 Score = 243 bits (619), Expect = 3e-63 Identities = 123/296 (41%), Positives = 186/296 (62%), Gaps = 8/296 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LG T+G G+F KVK+ + G A+K+L+R + +V +IKREI +KL RHP+ Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+++ + +MV+E+V GGELFD I G++ E EARR F Q+++AVDYCH V Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPEN+LLD++ K++DFGLS D L T+CG+PNY APEV++ + Y G Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGLSNI---MSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WSCG+IL+ L+ G LPFDD ++ TL+K I P + + L+ +L + Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252 Query: 914 PHTRITIAQILEDEWFKKDY------KPPLSEHN--EDVSLEDVDAAFDSSEEHLV 1057 P R TI I E EWFK+D + P + N +D ++++V F+ +E ++ Sbjct: 253 PLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVM 308
>P54646:AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Homo| sapiens (Human) Length = 552 Score = 243 bits (619), Expect = 3e-63 Identities = 123/296 (41%), Positives = 186/296 (62%), Gaps = 8/296 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LG T+G G+F KVK+ + G A+K+L+R + +V +IKREI +KL RHP+ Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+++ + +MV+E+V GGELFD I G++ E EARR F Q+++AVDYCH V Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPEN+LLD++ K++DFGL S D L T+CG+PNY APEV++ + Y G Sbjct: 136 VHRDLKPENVLLDAHMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WSCG+IL+ L+ G LPFDD ++ TL+K I P + + L+ +L + Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252 Query: 914 PHTRITIAQILEDEWFKKDY------KPPLSEHN--EDVSLEDVDAAFDSSEEHLV 1057 P R TI I E EWFK+D + P + N +D ++++V F+ +E ++ Sbjct: 253 PLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVM 308
>O74536:SNF1_SCHPO SNF1-like protein kinase ssp2 - Schizosaccharomyces pombe (Fission| yeast) Length = 576 Score = 241 bits (616), Expect = 6e-63 Identities = 136/345 (39%), Positives = 203/345 (58%), Gaps = 9/345 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y + +T+GEGSF KVK+A + A+K + R + + M +++REI+ +KL+RHP+ Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPH 93 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+ + + I MV+E+ GGELFD IV ++ EDE RR+F Q+I A++YCH + Sbjct: 94 IIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKI 152 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD +K++DFGLS D L T+CG+PNY APEV+ K Y G Sbjct: 153 VHRDLKPENLLLDDNLNVKIADFGLSNIMT---DGNFLKTSCGSPNYAAPEVINGKLYAG 209 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWSCGI+L+V++ G LPFDD + L+K ++ P + S GA++LI+R++ + Sbjct: 210 PEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMIVAD 269 Query: 914 PHTRITIAQILEDEWFK---KDYKPPLSE----HNEDVSLEDVDAAFDSSEEHLVAERR- 1069 P RITI +I D WF DY P+ E + + + + A SE+++V R Sbjct: 270 PMQRITIQEIRRDPWFNVNLPDYLRPMEEVQGSYADSRIVSKLGEAMGFSEDYIVEALRS 329 Query: 1070 -EKPESMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTP 1201 E E A+ L+ + EK + KR SF S P Sbjct: 330 DENNEVKEAYNLLHENQVIQ-----EKSHLSKSKRVDSFLSVSPP 369
>Q28948:AAPK2_PIG 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Sus| scrofa (Pig) Length = 552 Score = 241 bits (616), Expect = 6e-63 Identities = 123/296 (41%), Positives = 185/296 (62%), Gaps = 8/296 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LG T+G G+F KVK+ + G A+K+L+R + +V +IKREI +KL RHP+ Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+++ + +MV+E+V GGELFD I G++ E EARR F Q+++AVDYCH V Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV 135 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPEN+LLD+ K++DFGL S D L T+CG+PNY APEV++ + Y G Sbjct: 136 VHRDLKPENVLLDAQMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WSCG+IL+ L+ G LPFDD ++ TL+K I P + + L+ +L + Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVD 252 Query: 914 PHTRITIAQILEDEWFKKDY------KPPLSEHN--EDVSLEDVDAAFDSSEEHLV 1057 P R TI I E EWFK+D + P + N +D ++++V F+ +E ++ Sbjct: 253 PLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVM 308
>Q14680:MELK_HUMAN Maternal embryonic leucine zipper kinase - Homo sapiens (Human)| Length = 651 Score = 241 bits (615), Expect = 8e-63 Identities = 129/288 (44%), Positives = 178/288 (61%), Gaps = 2/288 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL +TIG G FAKVK+A G AIK++D+N + + +IK EI +K +RH + Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTL--GSDLPRIKTEIEALKNLRHQH 68 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 + QL+ V+ + +KI+MVLE+ GGELFD I++ +L E+E R F Q+++AV Y HS+G Sbjct: 69 ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGY 128 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLL D Y LK+ DFGL A P+ D L T CG+ Y APE++ K Y G Sbjct: 129 AHRDLKPENLLFDEYHKLKLIDFGLCA-KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLG 187 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 ADVWS GI+L+VLM G+LPFDD N+M LYK I R P W S + L++++L + Sbjct: 188 SEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVD 247 Query: 914 PHTRITIAQILEDEWFKKDYKPPL--SEHNEDVSLEDVDAAFDSSEEH 1051 P RI++ +L W +DY P+ N + L+D D + S H Sbjct: 248 PKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDD-DCVTELSVHH 294
>Q09137:AAPK2_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Rattus| norvegicus (Rat) Length = 552 Score = 241 bits (615), Expect = 8e-63 Identities = 123/296 (41%), Positives = 185/296 (62%), Gaps = 8/296 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LG T+G G+F KVK+ + G A+K+L+R + +V +IKREI +KL RHP+ Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+++ + +MV+E+V GGELFD I G++ E EARR F Q+++AVDYCH V Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMV 135 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPEN+LLD+ K++DFGL S D L T+CG+PNY APEV++ + Y G Sbjct: 136 VHRDLKPENVLLDAQMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WSCG+IL+ L+ G LPFDD ++ TL+K I P + + L+ +L + Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMHMLQVD 252 Query: 914 PHTRITIAQILEDEWFKKDY------KPPLSEHN--EDVSLEDVDAAFDSSEEHLV 1057 P R TI I E EWFK+D + P + N +D ++++V F+ +E ++ Sbjct: 253 PLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVM 308
>Q8BRK8:AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-2 - Mus| musculus (Mouse) Length = 552 Score = 240 bits (613), Expect = 1e-62 Identities = 117/259 (45%), Positives = 168/259 (64%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LG T+G G+F KVK+ + G A+K+L+R + +V +IKREI +KL RHP+ Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+++ + +MV+E+V GGELFD I G++ E EARR F Q+++AVDYCH V Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMV 135 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPEN+LLD+ K++DFGL S D L T+CG+PNY APEV++ + Y G Sbjct: 136 VHRDLKPENVLLDAQMNAKIADFGL---SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG 192 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WSCG+IL+ L+ G LPFDD ++ TL+K I P + + L+ +L + Sbjct: 193 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPDYLNRSVATLLMHMLQVD 252 Query: 914 PHTRITIAQILEDEWFKKD 970 P R TI I E EWFK+D Sbjct: 253 PLKRATIKDIREHEWFKQD 271
>Q95ZQ4:AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-2 -| Caenorhabditis elegans Length = 626 Score = 240 bits (612), Expect = 2e-62 Identities = 123/288 (42%), Positives = 180/288 (62%), Gaps = 4/288 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L +T+G G+F KVKV A+K+L+R + +V +I+REI + L RHP+ Sbjct: 87 YILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPH 146 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V+++ S I+M++E V GGELFD IV G+L EARR+F Q+I+ VDYCH V Sbjct: 147 IIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMV 206 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD +K++DFGLS D L T+CG+PNY APEV++ K Y G Sbjct: 207 VHRDLKPENLLLDEQNNVKIADFGLSNI---MTDGDFLRTSCGSPNYAAPEVISGKLYAG 263 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWSCG+IL+ L+ G LPFDD ++ +L++ I P + NL+ +L + Sbjct: 264 PEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHMLCVD 323 Query: 914 PHTRITIAQILEDEWFKKDYK----PPLSEHNEDVSLEDVDAAFDSSE 1045 P R TI ++ EWF+KD PP++E + S+ D++A + +E Sbjct: 324 PMKRATIKDVIAHEWFQKDLPNYLFPPINE--SEASIVDIEAVREVTE 369
>Q61846:MELK_MOUSE Maternal embryonic leucine zipper kinase - Mus musculus (Mouse)| Length = 643 Score = 238 bits (607), Expect = 7e-62 Identities = 127/282 (45%), Positives = 175/282 (62%), Gaps = 8/282 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL +TIG G FAKVK+A G AIK++D+N + + ++K EI +K +RH + Sbjct: 11 YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNAL--GSDLPRVKTEIDALKSLRHQH 68 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 + QL+ V+ +K+KI+MVLE+ GGELFD I++ +L E+E R F Q+++AV Y HS+G Sbjct: 69 ICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHSQGY 128 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLL D LK+ DFGL A P+ D L T CG+ Y APE++ K Y G Sbjct: 129 AHRDLKPENLLFDENHKLKLIDFGLCA-KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLG 187 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 ADVWS GI+L+VLM G+LPFDD N+M LYK I R P W S + L++++L + Sbjct: 188 SEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSILLLQQMLQVD 247 Query: 914 PHTRITIAQILEDEWFKKDY--------KPPLSEHNEDVSLE 1015 P RI++ +L W +DY K PL+ +ED E Sbjct: 248 PKKRISMRNLLNHPWVMQDYSCPVEWQSKTPLTHLDEDCVTE 289
>Q8TDC3:BRSK1_HUMAN BR serine/threonine-protein kinase 1 - Homo sapiens (Human)| Length = 794 Score = 229 bits (583), Expect = 4e-59 Identities = 108/256 (42%), Positives = 167/256 (65%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KT+G+G VK+ G AIK+++R L ++ +++REIA +KLI HP+ Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREK-LSESVLMKVEREIAILKLIEHPH 108 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 V++LH+V +K +Y+VLE V GGELFD +V G+L EAR++F Q+++A+D+CHS + Sbjct: 109 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 168 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD ++++DFG+++ D LL T+CG+P+Y PEV+ + YDG Sbjct: 169 CHRDLKPENLLLDEKNNIRIADFGMASLQ---VGDSLLETSCGSPHYACPEVIKGEKYDG 225 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 AD+WSCG+ILF L+ G LPFDD NL L + + R P + ++L++ +++ Sbjct: 226 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 285 Query: 914 PHTRITIAQILEDEWF 961 P R+++ QI + W+ Sbjct: 286 PEKRLSLEQIQKHPWY 301
>Q03141:MARK3_MOUSE MAP/microtubule affinity-regulating kinase 3 - Mus musculus (Mouse)| Length = 753 Score = 228 bits (582), Expect = 5e-59 Identities = 118/276 (42%), Positives = 172/276 (62%), Gaps = 4/276 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KTIG+G+FAKVK+A+ G AIK++D+ L ++++ RE+ MK++ HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 114 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L EV+ ++ +Y+++E+ GGE+FD +V G++ E EAR F Q+++AV YCH + + Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 174 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG FS + L T CG+P Y APE+ K YDG Sbjct: 175 VHRDLKAENLLLDADMNIKIADFG---FSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDG 231 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+IL+ L++G LPFD NL L + + R P + ST NL+KR L N Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 291 Query: 914 PHTRITIAQILEDEWF----KKDYKPPLSEHNEDVS 1009 P R T+ QI++D W ++D P E D+S Sbjct: 292 PVKRGTLEQIMKDRWINAGHEEDELKPFVEPELDIS 327
>Q5RJI5:BRSK1_MOUSE BR serine/threonine-protein kinase 1 - Mus musculus (Mouse)| Length = 778 Score = 228 bits (582), Expect = 5e-59 Identities = 107/256 (41%), Positives = 167/256 (65%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KT+G+G VK+ G A+K+++R L ++ +++REIA +KLI HP+ Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNREK-LSESVLMKVEREIAILKLIEHPH 92 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 V++LH+V +K +Y+VLE V GGELFD +V G+L EAR++F Q+++A+D+CHS + Sbjct: 93 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 152 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD ++++DFG+++ D LL T+CG+P+Y PEV+ + YDG Sbjct: 153 CHRDLKPENLLLDEKNNIRIADFGMASLQ---VGDSLLETSCGSPHYACPEVIKGEKYDG 209 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 AD+WSCG+ILF L+ G LPFDD NL L + + R P + ++L++ +++ Sbjct: 210 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 269 Query: 914 PHTRITIAQILEDEWF 961 P R+++ QI + W+ Sbjct: 270 PEKRLSLEQIQKHPWY 285
>O08679:MARK2_RAT Serine/threonine-protein kinase MARK2 - Rattus norvegicus (Rat)| Length = 722 Score = 228 bits (580), Expect = 9e-59 Identities = 116/277 (41%), Positives = 171/277 (61%), Gaps = 8/277 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KTIG+G+FAKVK+A+ G A+K++D+ L ++++ RE+ MK++ HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ-LNSSSLQKLFREVRIMKVLNHPN 111 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L EV+ ++ +Y+V+E+ GGE+FD +V G++ E EAR F Q+++AV YCH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG FS + L T CG+P Y APE+ K YDG Sbjct: 172 VHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDG 228 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+IL+ L++G LPFD NL L + + R P + ST NL+K+ L N Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILN 288 Query: 914 PHTRITIAQILEDEWFK--------KDYKPPLSEHNE 1000 P R T+ QI++D W K Y PL ++ + Sbjct: 289 PSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKD 325
>Q7KZI7:MARK2_HUMAN Serine/threonine-protein kinase MARK2 - Homo sapiens (Human)| Length = 788 Score = 228 bits (580), Expect = 9e-59 Identities = 116/277 (41%), Positives = 171/277 (61%), Gaps = 8/277 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KTIG+G+FAKVK+A+ G A+K++D+ L ++++ RE+ MK++ HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ-LNSSSLQKLFREVRIMKVLNHPN 111 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L EV+ ++ +Y+V+E+ GGE+FD +V G++ E EAR F Q+++AV YCH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG FS + L T CG+P Y APE+ K YDG Sbjct: 172 VHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDG 228 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+IL+ L++G LPFD NL L + + R P + ST NL+K+ L N Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILN 288 Query: 914 PHTRITIAQILEDEWFK--------KDYKPPLSEHNE 1000 P R T+ QI++D W K Y PL ++ + Sbjct: 289 PSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKD 325
>Q8VHF0:MARK3_RAT MAP/microtubule affinity-regulating kinase 3 - Rattus norvegicus| (Rat) Length = 797 Score = 227 bits (579), Expect = 1e-58 Identities = 117/276 (42%), Positives = 171/276 (61%), Gaps = 4/276 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KTIG+G+FAKVK+A+ G AIK++D+ L ++++ RE+ MK++ HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 114 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L EV+ ++ +Y+++E+ GGE+FD +V G++ E EAR F Q+++AV YCH + + Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 174 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG FS + L T CG+P Y APE+ K YDG Sbjct: 175 VHRDLKAENLLLDADMNIKITDFG---FSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDG 231 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+IL+ L++G LPFD NL L + + R P + ST NL+KR L N Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLN 291 Query: 914 PHTRITIAQILEDEWFKKDYK----PPLSEHNEDVS 1009 P R T+ QI++D W ++ P E D+S Sbjct: 292 PVKRGTLEQIMKDRWINAGHEEEELKPFVEPELDIS 327
>O08678:MARK1_RAT Serine/threonine-protein kinase MARK1 - Rattus norvegicus (Rat)| Length = 793 Score = 227 bits (579), Expect = 1e-58 Identities = 123/317 (38%), Positives = 189/317 (59%), Gaps = 11/317 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KTIG+G+FAKVK+A+ G A+K++D+ L ++++ RE+ MK++ HPN Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 118 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L EV+ ++ +Y+V+E+ GGE+FD +V G++ E EAR F Q+++AV YCH + + Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCI 178 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG FS + L T CG+P Y APE+ K YDG Sbjct: 179 VHRDLKAENLLLDADMNIKIADFG---FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+IL+ L++G LPFD NL L + + R P + ST NL+K++L N Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLLVLN 295 Query: 914 PHTRITIAQILEDEWFK--------KDYKPPLSEHNEDVSLE---DVDAAFDSSEEHLVA 1060 P R ++ QI++D W K Y P + N+ ++ + A D + LV+ Sbjct: 296 PIKRGSLEQIMKDRWMNVGHEEEELKPYSEPELDLNDAKRIDIMVTMGFARDEINDALVS 355 Query: 1061 ERREKPESMNAFALISR 1111 ++ + E M + L+ R Sbjct: 356 QKYD--EVMATYILLGR 370
>Q8VHJ5:MARK1_MOUSE Serine/threonine-protein kinase MARK1 - Mus musculus (Mouse)| Length = 795 Score = 227 bits (579), Expect = 1e-58 Identities = 123/317 (38%), Positives = 189/317 (59%), Gaps = 11/317 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KTIG+G+FAKVK+A+ G A+K++D+ L ++++ RE+ MK++ HPN Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 118 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L EV+ ++ +Y+V+E+ GGE+FD +V G++ E EAR F Q+++AV YCH + + Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCI 178 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG FS + L T CG+P Y APE+ K YDG Sbjct: 179 VHRDLKAENLLLDADMNIKIADFG---FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+IL+ L++G LPFD NL L + + R P + ST NL+K++L N Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLLVLN 295 Query: 914 PHTRITIAQILEDEWFK--------KDYKPPLSEHNEDVSLE---DVDAAFDSSEEHLVA 1060 P R ++ QI++D W K Y P + N+ ++ + A D + LV+ Sbjct: 296 PIKRGSLEQIMKDRWMNVGHEEEELKPYSEPELDLNDAKRIDIMVTMGFARDEINDALVS 355 Query: 1061 ERREKPESMNAFALISR 1111 ++ + E M + L+ R Sbjct: 356 QKYD--EVMATYILLGR 370
>Q9P0L2:MARK1_HUMAN Serine/threonine-protein kinase MARK1 - Homo sapiens (Human)| Length = 795 Score = 226 bits (576), Expect = 3e-58 Identities = 122/315 (38%), Positives = 184/315 (58%), Gaps = 9/315 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KTIG+G+FAKVK+A+ G A+K++D+ L ++++ RE+ MK++ HPN Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 118 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L EV+ ++ +Y+V+E+ GGE+FD +V G++ E EAR F Q+++AV YCH + + Sbjct: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD +K++DFG FS + L T CG+P Y APE+ K YDG Sbjct: 179 VHRDLKAENLLLDGDMNIKIADFG---FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+IL+ L++G LPFD NL L + + R P + ST NL+K++L N Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLN 295 Query: 914 PHTRITIAQILEDEWFK--------KDYKPPLSEHNEDVSLE-DVDAAFDSSEEHLVAER 1066 P R ++ QI++D W K Y P + N+ ++ V F E + Sbjct: 296 PIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALIN 355 Query: 1067 REKPESMNAFALISR 1111 ++ E M + L+ R Sbjct: 356 QKYDEVMATYILLGR 370
>P57059:SN1L1_HUMAN Serine/threonine-protein kinase SNF1-like kinase 1 - Homo sapiens| (Human) Length = 783 Score = 226 bits (575), Expect = 3e-58 Identities = 124/315 (39%), Positives = 186/315 (59%), Gaps = 11/315 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ +T+G+G+FA VK+A+ AIK++D+ L +E+I RE+ MKL+ HP+ Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR-LDSSNLEKIYREVQLMKLLNHPH 85 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++VM +K +Y+V EF + GE+FD + ++G L E+EAR+ F Q+++AV+YCH + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHI 145 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD +K++DFG F K L T CG+P Y APEV K Y+G Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGFGNF---YKSGEPLSTWCGSPPYAAPEVFEGKEYEG 202 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++L+VL+ G LPFD PNL TL + + P + S +LI+R+L + Sbjct: 203 PQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVD 262 Query: 914 PHTRITIAQILEDEWFKKD------YKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREK 1075 P RITIAQI + W + + P S H+ +L D D + L +R+ Sbjct: 263 PARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLGVDRQRT 322 Query: 1076 PESM-----NAFALI 1105 ES+ N FA I Sbjct: 323 VESLQNSSYNHFAAI 337
>Q8CIP4:MARK4_MOUSE MAP/microtubule affinity-regulating kinase 4 - Mus musculus (Mouse)| Length = 752 Score = 224 bits (572), Expect = 7e-58 Identities = 113/274 (41%), Positives = 171/274 (62%), Gaps = 4/274 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L +TIG+G+FAKVK+A+ G AIK++D+ L ++++ RE+ MK + HPN Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPSSLQKLFREVRIMKGLNHPN 117 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L EV+ ++ +Y+V+E+ GE+FD +V+ G++ E EAR F Q+++AV YCH + + Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG FS + L T CG+P Y APE+ K YDG Sbjct: 178 VHRDLKAENLLLDAEANIKIADFG---FSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDG 234 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G+IL+ L++G LPFD NL L + + R P + ST ++++R L N Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLN 294 Query: 914 PHTRITIAQILEDEWFKKDYK----PPLSEHNED 1003 P R T+ QI++D+W Y+ P +E ED Sbjct: 295 PAKRCTLEQIMKDKWINIGYEGEELKPYTEPEED 328
>Q96L34:MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 - Homo sapiens (Human)| Length = 752 Score = 224 bits (572), Expect = 7e-58 Identities = 113/274 (41%), Positives = 171/274 (62%), Gaps = 4/274 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L +TIG+G+FAKVK+A+ G AIK++D+ L ++++ RE+ MK + HPN Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPSSLQKLFREVRIMKGLNHPN 117 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L EV+ ++ +Y+V+E+ GE+FD +V+ G++ E EAR F Q+++AV YCH + + Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG FS + L T CG+P Y APE+ K YDG Sbjct: 178 VHRDLKAENLLLDAEANIKIADFG---FSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDG 234 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G+IL+ L++G LPFD NL L + + R P + ST ++++R L N Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLN 294 Query: 914 PHTRITIAQILEDEWFKKDYK----PPLSEHNED 1003 P R T+ QI++D+W Y+ P +E ED Sbjct: 295 PAKRCTLEQIMKDKWINIGYEGEELKPYTEPEED 328
>Q05512:MARK2_MOUSE Serine/threonine-protein kinase MARK2 - Mus musculus (Mouse)| Length = 776 Score = 224 bits (572), Expect = 7e-58 Identities = 115/277 (41%), Positives = 170/277 (61%), Gaps = 8/277 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KTIG+G+FAKVK+A+ G A+K++D+ L ++++ RE+ MK++ HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQ-LNSSSLQKLFREVRIMKVLNHPN 111 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L EV+ ++ +Y+V+E+ GGE+FD +V G++ E EAR F Q+++AV YCH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG FS + L T CG+P Y APE+ K DG Sbjct: 172 VHRDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKIDG 228 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+IL+ L++G LPFD NL L + + R P + ST NL+K+ L N Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILN 288 Query: 914 PHTRITIAQILEDEWFK--------KDYKPPLSEHNE 1000 P R T+ QI++D W K Y PL ++ + Sbjct: 289 PSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKD 325
>Q9R1U5:SN1L1_RAT Serine/threonine-protein kinase SNF1-like kinase 1 - Rattus| norvegicus (Rat) Length = 776 Score = 224 bits (570), Expect = 1e-57 Identities = 112/259 (43%), Positives = 166/259 (64%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ +T+G+G+FA VK+A+ AIK++D+ L +E+I RE+ MKL+ HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR-LDSSNLEKIYREVQLMKLLNHPN 85 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++VM +K +Y+V EF + GE+FD + ++G L E+EAR+ F Q+++AV+YCH+ + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHNHHI 145 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD +K++DFG F K L T CG+P Y APEV K Y+G Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGFGNF---YKPGEPLSTWCGSPPYAAPEVFEGKEYEG 202 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++L+VL+ G LPFD PNL TL + + P + S LI+R+L + Sbjct: 203 PQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVD 262 Query: 914 PHTRITIAQILEDEWFKKD 970 P RITIAQI + W + D Sbjct: 263 PAKRITIAQIRQHRWMQAD 281
>Q8IWQ3:BRSK2_HUMAN BR serine/threonine-protein kinase 2 - Homo sapiens (Human)| Length = 736 Score = 224 bits (570), Expect = 1e-57 Identities = 115/285 (40%), Positives = 173/285 (60%), Gaps = 8/285 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KT+G+G VK+ AIK+++R L ++ +++REIA +KLI HP+ Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREK-LSESVLMKVEREIAILKLIEHPH 77 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 V++LH+V +K +Y+VLE V GGELFD +V G+L EAR++F Q+I+A+D+CHS + Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD ++++DFG+++ D LL T+CG+P+Y PEV+ + YDG Sbjct: 138 CHRDLKPENLLLDEKNNIRIADFGMASLQ---VGDSLLETSCGSPHYACPEVIRGEKYDG 194 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 ADVWSCG+ILF L+ G LPFDD NL L + + R P + ++L++ +++ + Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVD 254 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEH--------NEDVSLEDVD 1024 R+T+ I + W+ P E SLED+D Sbjct: 255 AARRLTLEHIQKHIWYIGGKNEPEPEQPIPRKVQIRSLPSLEDID 299
>Q9IA88:SN1L2_CHICK Serine/threonine-protein kinase SNF1-like kinase 2 - Gallus gallus| (Chicken) Length = 798 Score = 223 bits (569), Expect = 2e-57 Identities = 116/286 (40%), Positives = 174/286 (60%), Gaps = 15/286 (5%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ +T+G+G+FA VK+A+ AIK++D+ L +E+I RE+ MKL+ HP+ Sbjct: 26 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR-LDPSNLEKIYREVQIMKLLNHPH 84 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++VM +K +Y+V EF + GE+FD + ++G L E EAR+ F Q+++AV+YCHS + Sbjct: 85 IIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHI 144 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG F K L T CG+P Y APEV K Y+G Sbjct: 145 VHRDLKTENLLLDANMNIKLADFGFGNF---YKSGEPLSTWCGSPPYAAPEVFEGKEYEG 201 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++L+VL+ G LPFD PNL TL + + P + S LI+R+L + Sbjct: 202 PHLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEDCETLIRRMLVVD 261 Query: 914 PHTRITIAQILEDEWFKKD---------------YKPPLSEHNEDV 1006 P RITI+QI + +W + D Y L ++NE V Sbjct: 262 PTKRITISQIKQHKWMQADPSLRQQQSLSFSMQNYNSNLGDYNEQV 307
>Q60670:SN1L1_MOUSE Serine/threonine-protein kinase SNF1-like kinase 1 - Mus musculus| (Mouse) Length = 779 Score = 223 bits (569), Expect = 2e-57 Identities = 120/281 (42%), Positives = 174/281 (61%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ +T+G+G+FA VK+A+ AIK++D+ L +E+I RE+ MKL+ HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTR-LDSSNLEKIYREVQLMKLLNHPN 85 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++VM +K +Y+V EF + GE+FD + ++G L E+EAR+ F Q+++AV+YCH+ + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCHNHHI 145 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLDS +K++DFG F K L T G+P Y APEV K Y+G Sbjct: 146 VHRDLKTENLLLDSNMDIKLADFGFGNF---YKPGEPLSTCVGSPPYAAPEVFEGKEYEG 202 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G++L+VL+ G LPFD PNL TL + + P + S LI+R+L + Sbjct: 203 PQLDVWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVD 262 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFD 1036 P RITIAQI + W + D P L L+ D AFD Sbjct: 263 PAKRITIAQIRQHRWMQAD--PTL--------LQQDDPAFD 293
>Q69Z98:BRSK2_MOUSE BR serine/threonine-protein kinase 2 - Mus musculus (Mouse)| Length = 735 Score = 223 bits (569), Expect = 2e-57 Identities = 115/285 (40%), Positives = 173/285 (60%), Gaps = 8/285 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KT+G+G VK+ AIK+++R L ++ +++REIA +KLI HP+ Sbjct: 20 YRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREK-LSESVLMKVEREIAILKLIEHPH 78 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 V++LH+V +K +Y+VLE V GGELFD +V G+L EAR++F Q+I+A+D+CHS + Sbjct: 79 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 138 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD ++++DFG+++ D LL T+CG+P+Y PEV+ + YDG Sbjct: 139 CHRDLKPENLLLDERNNIRIADFGMASLQ---VGDSLLETSCGSPHYACPEVIRGEKYDG 195 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 ADVWSCG+ILF L+ G LPFDD NL L + + R P + ++L++ +++ + Sbjct: 196 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVD 255 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEH--------NEDVSLEDVD 1024 R+T+ I + W+ P E SLED+D Sbjct: 256 AARRLTLEHIQKHIWYIGGKNEPEPEQPIPRKVQIRSLPSLEDID 300
>Q9H0K1:SN1L2_HUMAN Serine/threonine-protein kinase SNF1-like kinase 2 - Homo sapiens| (Human) Length = 926 Score = 223 bits (567), Expect = 3e-57 Identities = 115/285 (40%), Positives = 175/285 (61%), Gaps = 14/285 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ T+G+G+FA VK+ + AIK++D++ L +E+I RE+ MK++ HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQ-LDAVNLEKIYREVQIMKMLDHPH 78 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++VM +KS +Y+V E+ + GE+FD + N G+L E EARR F Q+++AVDYCH R + Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG F K LL T CG+P Y APEV + Y+G Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNF---FKSGELLATWCGSPPYAAPEVFEGQQYEG 195 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++L+VL+ G LPFD P L L + + P + S +LI+R+L + Sbjct: 196 PQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLD 255 Query: 914 PHTRITIAQILEDEWF--------------KKDYKPPLSEHNEDV 1006 P R+TIAQI E +W +++ +P + E NE V Sbjct: 256 PSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQV 300
>Q02723:RKIN1_SECCE Carbon catabolite derepressing protein kinase - Secale cereale| (Rye) Length = 502 Score = 223 bits (567), Expect = 3e-57 Identities = 117/260 (45%), Positives = 167/260 (64%), Gaps = 3/260 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKL---IR 364 Y LGK +G G+FAKV +A+ AIKVL+R + +M E+ KREI ++L + Sbjct: 14 YYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRLFIDLI 73 Query: 365 HPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHS 544 HP++++++EV+ + I++V+E+ + G+L D I+ +L EDEARR F Q+I+AV+YCH Sbjct: 74 HPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVEYCHR 133 Query: 545 RGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 V HRDLKPENLLLDS +K++DFGLS D L T+CG+ NY APEV++ K Sbjct: 134 NKVVHRDLKPENLLLDSKYNVKLADFGLSNV---MHDGHFLKTSCGSLNYAAPEVISGKL 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 Y G DVWSCG+IL+ L+ G +PFDD N+ L+K I P + S R+LI R+L Sbjct: 191 YAGPEIDVWSCGVILYALLCGAVPFDDDNIPNLFKKIKGGTYILPIYLSDLVRDLISRML 250 Query: 905 DPNPHTRITIAQILEDEWFK 964 +P RITI +I + WF+ Sbjct: 251 IVDPMKRITIGEIRKHSWFQ 270
>Q8CFH6:SN1L2_MOUSE Serine/threonine-protein kinase SNF1-like kinase 2 - Mus musculus| (Mouse) Length = 931 Score = 222 bits (565), Expect = 5e-57 Identities = 115/285 (40%), Positives = 175/285 (61%), Gaps = 14/285 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ T+G+G+FA VK+ + AIK++D++ L +E+I RE+ MK++ HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQ-LDAVNLEKIYREVQIMKMLDHPH 78 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++VM +KS +Y+V E+ + GE+FD + N G+L E EARR F Q+++AVDYCH R V Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKV 138 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DFG F K LL T CG+P Y APEV + Y+G Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNF---FKTGELLATWCGSPPYAAPEVFEGQQYEG 195 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++L+VL+ G LPFD P L L + + P + S +LI+R+L + Sbjct: 196 PQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLD 255 Query: 914 PHTRITIAQILEDEWF--------------KKDYKPPLSEHNEDV 1006 P R++IAQI E +W +++ +P + E NE V Sbjct: 256 PSKRLSIAQIKEHKWMLIEVPVQRPILYPQEQENEPSIGEFNEQV 300
>P34244:HSL1_YEAST Probable serine/threonine-protein kinase HSL1 - Saccharomyces| cerevisiae (Baker's yeast) Length = 1518 Score = 220 bits (561), Expect = 1e-56 Identities = 125/324 (38%), Positives = 184/324 (56%), Gaps = 36/324 (11%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRH-------------KMVEQ-- 328 ++LGKT+G+GS +V++AK+ G AIK++ + H MV Sbjct: 81 WKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNV 140 Query: 329 --------------------IKREIATMKLIRHPNVVQLHEVMASKSKIYMVLEFVEGGE 448 I+REI MKLI H NV+ L EV +KS++Y+VLE+V+GGE Sbjct: 141 SSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGE 200 Query: 449 LFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDSYG-ALKVSDFG 625 LFD +V+ GKL E EA YF Q++ V YCHS + HRDLKPENLLLD +K++DFG Sbjct: 201 LFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFG 260 Query: 626 LSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDD 805 ++A K LL T+CG+P+Y +PE++ + Y G +DVWSCGI+LF L+ G+LPF+D Sbjct: 261 MAALELPNK---LLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFND 317 Query: 806 PNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPL 985 N+ L + P S+ AR+LI +IL +P RIT +IL+ KK P+ Sbjct: 318 DNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPV 377 Query: 986 SEHNEDVSLEDVDAAFDSSEEHLV 1057 ++ + +++ +S+ HL+ Sbjct: 378 NKVLRKMRKDNMARGKSNSDLHLL 401
>P27448:MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 - Homo sapiens (Human)| Length = 776 Score = 218 bits (554), Expect = 9e-56 Identities = 119/299 (39%), Positives = 173/299 (57%), Gaps = 27/299 (9%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y L KTIG+G+FAKVK+A+ G AIK++D+ L ++++ RE+ MK++ HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ-LNPTSLQKLFREVRIMKILNHPN 114 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQ------------- 514 +V+L EV+ ++ +Y+++E+ GGE+FD +V G++ E EAR F Q Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKVQVS 174 Query: 515 ----------LINAVDYCHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGL 664 +++AV YCH + + HRDLK ENLLLD+ +K++DFG FS + G Sbjct: 175 FDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFG---FSNEFTVGGK 231 Query: 665 LHTACGTPNYVAPEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA 844 L T CG+P Y APE+ K YDG DVWS G+IL+ L++G LPFD NL L + + R Sbjct: 232 LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG 291 Query: 845 NVSCPPWFSTGARNLIKRILDPNPHTRITIAQILEDEWF----KKDYKPPLSEHNEDVS 1009 P + ST NL+KR L NP R T+ QI++D W ++D P E D+S Sbjct: 292 KYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDIS 350
>P45894:AAPK1_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-1 -| Caenorhabditis elegans Length = 589 Score = 216 bits (550), Expect = 3e-55 Identities = 114/291 (39%), Positives = 172/291 (59%), Gaps = 1/291 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 + + +TIG+G+F VK + G AIK+L+R + V + + EI ++ + HP+ Sbjct: 24 FVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHPH 83 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 + +L V+++ S I++V+E V GGELF I G L E+RRYF Q+I+ V YCH+ + Sbjct: 84 ITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHMI 143 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD+ +K++DFGLS + D LL TACG+PNY APE++++K Y G Sbjct: 144 VHRDLKPENLLLDANKNIKIADFGLSNY---MTDGDLLSTACGSPNYAAPELISNKLYVG 200 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WSCG+IL+ ++ G LPFDD N+ TL+ I + P A +LI +L + Sbjct: 201 PEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTMLQVD 260 Query: 914 PHTRITIAQILEDEWFKKDYKPPL-SEHNEDVSLEDVDAAFDSSEEHLVAE 1063 P R + +I+ WF+ D L E + S+ D+D +E+ V E Sbjct: 261 PVKRADVKRIVNHSWFRIDLPYYLFPECENESSIVDIDVVQSVAEKFDVKE 311
>Q5REX1:SN1L2_PONPY Serine/threonine-protein kinase SNF1-like kinase 2 - Pongo pygmaeus| (Orangutan) Length = 925 Score = 216 bits (549), Expect = 3e-55 Identities = 113/285 (39%), Positives = 173/285 (60%), Gaps = 14/285 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ T+G+G+FA VK+ + AIK++D++ L +E+I RE+ MK++ HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQ-LDAVNLEKIYREVQIMKMLDHPH 78 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++VM +KS +Y+V E+ + GE+FD + N G+L E EARR F Q+++AVDYCH R + Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD+ +K++DF F K LL T G+P Y APEV + Y+G Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFSFGNF---FKSGELLATWRGSPPYAAPEVFEGQQYEG 195 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++L+VL+ G LPFD P L L + + P + S +LI+R+L + Sbjct: 196 PQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLD 255 Query: 914 PHTRITIAQILEDEWF--------------KKDYKPPLSEHNEDV 1006 P R+TIAQI E +W +++ +P + E NE V Sbjct: 256 PSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQV 300
>Q9Y2K2:QSK_HUMAN Serine/threonine-protein kinase QSK - Homo sapiens (Human)| Length = 1263 Score = 214 bits (544), Expect = 1e-54 Identities = 125/329 (37%), Positives = 186/329 (56%), Gaps = 1/329 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+ +TIG+G+FA VK A A AIK++D+ L + +++I RE+ MK++ HP+ Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQ-LDEENLKKIFREVQIMKMLCHPH 66 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++VM ++ IY+V E+ GGE+FD +V G++ E EARR F Q++ AV +CH R + Sbjct: 67 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 126 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLS-AFSPQTKDDGLLHTACGTPNYVAPEVLADKGYD 730 HRDLK ENLLLD+ +K++DFG S F+P LL T CG+P Y APE+ K YD Sbjct: 127 VHRDLKAENLLLDANLNIKIADFGFSNLFTP----GQLLKTWCGSPPYAAPELFEGKEYD 182 Query: 731 GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDP 910 G D+WS G++L+VL+ G LPFD L L + P + ST +LI+ +L Sbjct: 183 GPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVL 242 Query: 911 NPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREKPESMN 1090 +P+ R+++ QI + +W K L D D FD L+AE ++ E Sbjct: 243 DPNKRLSMEQICKHKWMK---------------LGDADPNFD----RLIAECQQLKEERQ 283 Query: 1091 AFALISRSAGFNLGNLFEKEMMGMVKRET 1177 L N L E MG+ K +T Sbjct: 284 VDPL-------NEDVLLAMEDMGLDKEQT 305
>Q6P4S6:QSK_MOUSE Serine/threonine-protein kinase QSK - Mus musculus (Mouse)| Length = 1311 Score = 213 bits (542), Expect = 2e-54 Identities = 125/329 (37%), Positives = 186/329 (56%), Gaps = 1/329 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+ +TIG+G+FA VK A A AIK++D++ L + +++I RE+ MK++ HP+ Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQ-LDEENLKKIFREVQIMKMLCHPH 66 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++VM ++ IY+V E+ GGE+FD +V G++ E EARR F Q++ AV +CH R + Sbjct: 67 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 126 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLS-AFSPQTKDDGLLHTACGTPNYVAPEVLADKGYD 730 HRDLK ENLLLD+ +K++DFG S F+P LL T CG+P Y APE+ K YD Sbjct: 127 VHRDLKAENLLLDANLNIKIADFGFSNLFTP----GQLLKTWCGSPPYAAPELFEGKEYD 182 Query: 731 GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDP 910 G D+WS G++L+VL+ G LPFD L L + P + ST +LI+ +L Sbjct: 183 GPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVL 242 Query: 911 NPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREKPESMN 1090 +P+ R+++ QI +W K L D D FD L+AE ++ E Sbjct: 243 DPNKRLSMEQICRHKWMK---------------LGDADPNFD----RLIAECQQLKEE-- 281 Query: 1091 AFALISRSAGFNLGNLFEKEMMGMVKRET 1177 +S N L E MG+ K T Sbjct: 282 -----RQSDPLNDDVLLAMEDMGLDKERT 305
>P25389:KCC4_YEAST Probable serine/threonine-protein kinase KCC4 - Saccharomyces| cerevisiae (Baker's yeast) Length = 1037 Score = 210 bits (535), Expect = 1e-53 Identities = 114/270 (42%), Positives = 168/270 (62%), Gaps = 12/270 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDR-------NHVLRHKMVE-QIKREIAT 349 ++LG+T+G GS KV++A+ R G A+KV+ + NH ++ I+REI Sbjct: 21 WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVI 80 Query: 350 MKLIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAV 529 MKL+ HPNV+ L++V + + +Y++LE+ E GELF+ +V+ G L E EA F Q+I + Sbjct: 81 MKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGI 140 Query: 530 DYCHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEV 709 YCH+ G+ HRDLKPENLLLDS+ +K++DFG++A D LL T+CG+P+Y APE+ Sbjct: 141 SYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQ---TDADLLETSCGSPHYAAPEI 197 Query: 710 LADKGYDGMAADVWSCGIILFVLMAGYLPFDDP--NLMTLYKLISRANVSCP--PWFSTG 877 ++ Y+G A+DVWSCG+ILF L+ G LPFD+ N+ L + + P S Sbjct: 198 VSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRD 257 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKK 967 A++LI +IL +P RI I IL KK Sbjct: 258 AQDLIGKILVVDPRQRIKIRDILSHPLLKK 287
>Q12263:GIN4_YEAST Serine/threonine-protein kinase GIN4 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1142 Score = 210 bits (535), Expect = 1e-53 Identities = 131/370 (35%), Positives = 199/370 (53%), Gaps = 38/370 (10%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDR-----NHVLRHKMVEQ---------I 331 ++LG+T+G GS KV++A++ G A+KV+ + +V +V I Sbjct: 19 WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGI 78 Query: 332 KREIATMKLIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFH 511 +REI MKL+ HPNV++L++V + + +Y+VLE+ E GELF+ +V G L E EA R+F Sbjct: 79 EREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFR 138 Query: 512 QLINAVDYCHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPN 691 Q+I V YCH+ G+ HRDLKPENLLLD +K++DFG++A + K LL T+CG+P+ Sbjct: 139 QIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGK---LLETSCGSPH 195 Query: 692 YVAPEVLADKGYDGMAADVWSCGIILFVLMAGYLPFD--DPNLMTLYKLISRANVSCP-- 859 Y APE+++ Y G A+DVWSCG+ILF L+ G LPFD D N+ TL + + P Sbjct: 196 YAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSD 255 Query: 860 PWFSTGARNLIKRILDPNPHTRITIAQILEDEWFKK-----------------DYKPPLS 988 S A++LI++IL +P RI IL+ +K Y PLS Sbjct: 256 DEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSIRDSKSIRGLPREDTYLTPLS 315 Query: 989 EHNEDVS---LEDVDAAFDSSEEHLVAERREKPESMNAFALISRSAGFNLGNLFEKEMMG 1159 E N + L+++ + + + E+ +P + L + F E Sbjct: 316 ESNSSIDATILQNLVILWHGRDPEGIKEKLREPGANAEKTLYALLYRFKCDTQKELIKQQ 375 Query: 1160 MVKRETSFAS 1189 VK+ S +S Sbjct: 376 QVKKRQSISS 385
>Q6NSM8:QSK_DANRE Serine/threonine-protein kinase QSK homolog - Danio rerio| (Zebrafish) (Brachydanio rerio) Length = 1187 Score = 210 bits (534), Expect = 2e-53 Identities = 107/263 (40%), Positives = 163/263 (61%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+ +TIG+G+FA VK+A A AIK++D+ L + +++I RE+ MK++RHP+ Sbjct: 59 YEMERTIGKGNFAVVKLATHMITKAKVAIKIVDKTQ-LDDENLKKIFREVQIMKMLRHPH 117 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++VM ++ IY+V E+ GGE+FD +V G++ E +ARR F Q++ AV +CH R + Sbjct: 118 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKDARRKFKQIVAAVYFCHCRSI 177 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK ENLLLD +K++DFG FS LL T CG+P Y APE+ K YDG Sbjct: 178 VHRDLKAENLLLDHNLNIKIADFG---FSNLFSRGQLLKTWCGSPPYAAPELFEGKEYDG 234 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++L+VL+ G LPFD L L + P + ST LI+ +L Sbjct: 235 PKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTDCEYLIRHMLILE 294 Query: 914 PHTRITIAQILEDEWFKKDYKPP 982 P R+++ QI +++W ++ P Sbjct: 295 PSRRLSMEQICKNKWMRQGDPDP 317
>Q84TC6:SAPK2_ORYSA Serine/threonine-protein kinase SAPK2 - Oryza sativa (Rice)| Length = 339 Score = 207 bits (528), Expect = 9e-53 Identities = 123/316 (38%), Positives = 176/316 (55%), Gaps = 14/316 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+ K IG G+F K+ +D R A+K ++R K+ E ++REI + +RHPN Sbjct: 4 YEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQ----KIDENVQREIMNHRSLRHPN 59 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+ EV+ + + + +V+E+ GGELF++I ++G+ EDEAR +F QLI+ V YCHS + Sbjct: 60 IVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQI 119 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD A LK+ DFG S S LLH + GTP Y+APEVLA Sbjct: 120 CHRDLKLENTLLDGSIAPRLKICDFGYSKSS-------LLHSQPKSTVGTPAYIAPEVLA 172 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDDP----NLMTLYKLISRANVSCPPW--FSTG 877 K YDG ADVWSCG+ L+V++ G PF+DP N I P + S Sbjct: 173 RKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYMVPDYVRVSME 232 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLS-EHNEDVSLEDVDAAFDSSEEHL 1054 R+L+ RI NP RITI +I WF K+ ++ E+ V + D++ EE + Sbjct: 233 CRHLLSRIFVANPEQRITIPEIKNHPWFLKNLPIEMTDEYQMSVQMNDINTPSQGLEEIM 292 Query: 1055 -VAERREKPESMNAFA 1099 + + KP + F+ Sbjct: 293 AIIQEARKPGDGSKFS 308
>Q75LR7:SAPK1_ORYSJ Serine/threonine-protein kinase SAPK1 - Oryza sativa subsp. japonica| (Rice) Length = 342 Score = 204 bits (519), Expect = 1e-51 Identities = 120/313 (38%), Positives = 176/313 (56%), Gaps = 15/313 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+ + IG G+F K+ +D A+K ++R K+ E ++REI + ++HPN Sbjct: 4 YEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIERGL----KIDEHVQREIMNHRSLKHPN 59 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV+ + + + +V+E+ GGELF++I N+G+ EDEAR +F QLI+ V YCHS V Sbjct: 60 IIRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQV 119 Query: 554 YHRDLKPENLLLDS--YGALKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD LK+ DFG S S +LH + GTP Y+APEVL+ Sbjct: 120 CHRDLKLENTLLDGSVTPRLKICDFGYSKSS-------VLHSQPKSTVGTPAYIAPEVLS 172 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDDP----NLMTLYKLISRANVSCPPW--FSTG 877 K YDG ADVWSCG+ L+V++ G PF+DP N I S P + S Sbjct: 173 RKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDDPRNFRKTITRILSVQYSIPDYVRVSAD 232 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLS-EHNEDVSLEDVDAAFDSSEE-- 1048 R+L+ RI NP RITI +I WF K+ ++ E+ + L D++ S EE Sbjct: 233 CRHLLSRIFVGNPEQRITIPEIKNHPWFLKNLPIEMTDEYQRSMQLADMNTPSQSLEEVM 292 Query: 1049 HLVAERREKPESM 1087 ++ E R+ ++M Sbjct: 293 AIIQEARKPGDAM 305
>P87050:CDR2_SCHPO Mitosis inducer protein kinase cdr2 - Schizosaccharomyces pombe| (Fission yeast) Length = 775 Score = 204 bits (518), Expect = 1e-51 Identities = 97/265 (36%), Positives = 163/265 (61%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +ELG ++G G ++AK G +K + L +I+ E+ ++LI HPN Sbjct: 10 WELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPN 69 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 V+QL +V++++ ++++V+E++ GGELFD ++ G E + ++ Q++ ++YCH + Sbjct: 70 VLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHI 129 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENL LD++G++K+ +FG+++ K LL T+CG+P+Y +PE++ + YDG Sbjct: 130 CHRDLKPENLYLDAHGSIKIGEFGMASIQQPGK---LLQTSCGSPHYASPEIIMGRSYDG 186 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A+D+WSCGII F L+ G LPFDD N+ +L + + P S A++L+ R+LD + Sbjct: 187 CASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPSNISPQAQHLLYRMLDVD 246 Query: 914 PHTRITIAQILEDEWFKKDYKPPLS 988 TRIT+ QI E + P +S Sbjct: 247 SSTRITMEQIREHPFLSCFVHPNIS 271
>Q75H77:SAPKA_ORYSJ Serine/threonine-protein kinase SAPK10 - Oryza sativa subsp. japonica| (Rice) Length = 362 Score = 203 bits (517), Expect = 2e-51 Identities = 119/298 (39%), Positives = 170/298 (57%), Gaps = 13/298 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL + IG G+F ++ + +G A+K ++R K+ E ++REI + +RHPN Sbjct: 23 YELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGD----KIDENVQREIINHRSLRHPN 78 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV+ + + + +V+E+ GGELF++I N+G+ EDEAR +F QLI+ V YCHS V Sbjct: 79 IIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQV 138 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD A LK+ DFG S S +LH + GTP Y+APEVL Sbjct: 139 CHRDLKLENTLLDGSTAPRLKICDFGYSKSS-------VLHSQPKSTVGTPAYIAPEVLL 191 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDDP----NLMTLYKLISRANVSCPPW--FSTG 877 K YDG ADVWSCG+ L+V++ G PF+DP N + I S P + S Sbjct: 192 KKEYDGKIADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILGVQYSIPDYVHISPE 251 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVS-LEDVDAAFDSSEE 1048 R+LI RI NP TRI+I +I WF K+ L + ++ S E+ + S +E Sbjct: 252 CRDLIARIFVANPATRISIPEIRNHPWFLKNLPADLMDDSKMSSQYEEPEQPMQSMDE 309
>Q75V57:SAPK9_ORYSJ Serine/threonine-protein kinase SAPK9 - Oryza sativa subsp.| japonica (Rice) Length = 361 Score = 202 bits (515), Expect = 3e-51 Identities = 115/278 (41%), Positives = 162/278 (58%), Gaps = 12/278 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL K IG G+F ++ ++ +G A+K +DR K+ E ++REI + +RHPN Sbjct: 22 YELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGE----KIDENVQREIINHRSLRHPN 77 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV+ + + + +V+E+ GGELF++I ++G+ EDEAR +F QLI+ V YCHS V Sbjct: 78 IIRFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQV 137 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD A LK+ DFG S S +LH + GTP Y+APEVL Sbjct: 138 CHRDLKLENTLLDGSTAPRLKICDFGYSKSS-------VLHSQPKSTVGTPAYIAPEVLL 190 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDDP----NLMTLYKLISRANVSCPPW--FSTG 877 K YDG ADVWSCG+ L+V++ G PF+DP N + I S P + S Sbjct: 191 KKEYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIQKILGVQYSIPDYVHISPE 250 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSE 991 R+LI RI NP +RIT+ +I WF K+ L + Sbjct: 251 CRDLITRIFVGNPASRITMPEIKNHPWFMKNIPADLMD 288
>Q75V63:SAPK3_ORYSA Serine/threonine-protein kinase SAPK3 - Oryza sativa (Rice)| Length = 334 Score = 200 bits (508), Expect = 2e-50 Identities = 116/291 (39%), Positives = 167/291 (57%), Gaps = 12/291 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE K +G G+F ++ +D R+ A+K ++R K+ E ++REI + +RHPN Sbjct: 5 YEALKELGAGNFGVARLVRDKRSKELVAVKYIERGK----KIDENVQREIINHRSLRHPN 60 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV + + + +V+E+ GGELF++I +G+ EDEAR +F QLI+ V YCHS + Sbjct: 61 IIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLEI 120 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD +K+ DFG S LLH + GTP Y+APEVL+ Sbjct: 121 CHRDLKLENTLLDGSPTPRVKICDFGYS-------KSALLHSKPKSTVGTPAYIAPEVLS 173 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDDP-NLMTLYKLISR---ANVSCPPW--FSTG 877 K YDG ADVWSCG+ L+V++ G PF+DP + K ISR S P + S+ Sbjct: 174 RKEYDGKVADVWSCGVTLYVMLVGSYPFEDPGDPRNFRKTISRILGVQYSIPDYVRVSSD 233 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAA 1030 R L+ +I +P RITI +I + WF K+ +SE E +D DAA Sbjct: 234 CRRLLSQIFVADPSKRITIPEIKKHTWFLKNLPKEISE-REKADYKDTDAA 283
>Q63553:SNRK_RAT SNF-related serine/threonine-protein kinase - Rattus norvegicus| (Rat) Length = 746 Score = 199 bits (507), Expect = 3e-50 Identities = 106/271 (39%), Positives = 165/271 (60%), Gaps = 3/271 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L KT+G G FA VK+A+ G A+KV+D+ L + +E+ MKL++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPN 74 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGK-LGEDEARRYFHQLINAVDYCHSRG 550 +V+L+EV+ +++K+Y++LE +GG++FD I+ + L ED A++YF Q+++A+ YCH Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134 Query: 551 VYHRDLKPENLLL-DSYGALKVSDFGLS-AFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 V HRDLKPEN++ + G +K++DFG S F P K L T+CG+ Y APE+L Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK----LTTSCGSLAYSAPEILLGDE 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 YD A D+WS G+ILF+L+ G PF + N +I + PP S G R+LI R+L Sbjct: 191 YDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRML 250 Query: 905 DPNPHTRITIAQILEDEWFKKDYKPPLSEHN 997 +P R ++ +I W + P +++N Sbjct: 251 QRDPKRRASLEEIESHPWLQGVDPSPATKYN 281
>Q8VDU5:SNRK_MOUSE SNF-related serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 748 Score = 199 bits (507), Expect = 3e-50 Identities = 106/271 (39%), Positives = 165/271 (60%), Gaps = 3/271 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L KT+G G FA VK+A+ G A+KV+D+ L + +E+ MKL++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPN 74 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGK-LGEDEARRYFHQLINAVDYCHSRG 550 +V+L+EV+ +++K+Y++LE +GG++FD I+ + L ED A++YF Q+++A+ YCH Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134 Query: 551 VYHRDLKPENLLL-DSYGALKVSDFGLS-AFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 V HRDLKPEN++ + G +K++DFG S F P K L T+CG+ Y APE+L Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK----LTTSCGSLAYSAPEILLGDE 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 YD A D+WS G+ILF+L+ G PF + N +I + PP S G R+LI R+L Sbjct: 191 YDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRML 250 Query: 905 DPNPHTRITIAQILEDEWFKKDYKPPLSEHN 997 +P R ++ +I W + P +++N Sbjct: 251 QRDPKRRASLEEIESHPWLQGVDPSPATKYN 281
>Q6DE87:CHK1_XENLA Serine/threonine-protein kinase Chk1 - Xenopus laevis (African clawed| frog) Length = 474 Score = 199 bits (507), Expect = 3e-50 Identities = 136/460 (29%), Positives = 220/460 (47%), Gaps = 43/460 (9%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 ++L +T+GEG++ +V++A + + A+K++D E IK+EI +++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAA--DCPENIKKEICINRMLSHTN 66 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+ + + Y+ LE+ GGELFD+I + E +A+++F QLI V+Y HS G+ Sbjct: 67 IVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHSIGI 126 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLLD LK+SDFGL+ + LL+ CGT YVAPE++ + + Sbjct: 127 THRDIKPENLLLDERDQLKISDFGLATVFRHNGKERLLNKMCGTLPYVAPELIKSRAFHA 186 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPN-LMTLYKLISRANVSCPPW--FSTGARNLIKRIL 904 DVWSCGI+L ++AG LP+D PN + Y N PW S L+ ++L Sbjct: 187 DPVDVWSCGIVLTAMLAGELPWDQPNEVCQEYCDWKEKNHYLTPWKKISATPLALLCKML 246 Query: 905 DPNPHTRITIAQILEDEWFKKDYKPPL------SEHNEDVSL------EDVDAAFDSSEE 1048 NP +RITI I +D WF + K L S + D S+ D+D + S E Sbjct: 247 TENPQSRITIPDIKKDRWFTEIIKKGLKRSRVISGGSSDSSVLCKQIRSDIDISHFSHSE 306 Query: 1049 HLVAERREKPESMNAFALISRSAGF--NL---------------GNLFEKEMMG------ 1159 A +PE A A ++ + NL L +++G Sbjct: 307 EKTALSSTQPEPRTALATWDSNSSYIDNLVQGKGISFSQPACPDNMLLNSQLIGTPGSSQ 366 Query: 1160 -----MVKRETSFASQRTPQEIMSKIEEACGPLGFNVRKQNYKMKLKGDKTGRKGHLSVA 1324 +VKR T F ++ + S + + C +G+ ++K R L Sbjct: 367 NVWQRLVKRMTRFFTKVNAESSYSNLMDTCEKMGYVLKKSCANEVTLSTTDRRNNKLIFK 426 Query: 1325 TEVFEVAPSLHMVELRKTGGDTLEFHSFYQNFSSELKDIV 1444 + E+ + +++ R + GD LEF + ++ +V Sbjct: 427 VNLVEMEDRI-LLDFRLSKGDGLEFKRHFLKIKKKMDAVV 465
>Q02066:AAIP_WHEAT Abscisic acid-inducible protein kinase - Triticum aestivum (Wheat)| Length = 332 Score = 199 bits (505), Expect = 4e-50 Identities = 116/302 (38%), Positives = 168/302 (55%), Gaps = 14/302 (4%) Frame = +2 Query: 215 GEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQLHEV 394 G G+F K+ +D R A+K ++R H K+ E ++REI + ++HPN+++ EV Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIERGH----KIDEHVQREIMNHRSLKHPNIIRFKEV 56 Query: 395 MASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRDLKP 574 + + + + +V+E+ GGELF +I N+G+ EDE R +F QLI+ V YCHS V HRDLK Sbjct: 57 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSMQVCHRDLKL 116 Query: 575 ENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLADKGYDGM 736 EN LLD A LK+ DFG S S +LH + GTP Y+APEVL+ + YDG Sbjct: 117 ENTLLDGSVAPRLKICDFGYSKSS-------VLHSQPKSTVGTPAYIAPEVLSRREYDGK 169 Query: 737 AADVWSCGIILFVLMAGYLPFDDP----NLMTLYKLISRANVSCPPW--FSTGARNLIKR 898 ADVWSCG+ L+V++ G PF+DP N I S P + S +L+ R Sbjct: 170 VADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYSVPDYVRVSMDCIHLLSR 229 Query: 899 ILDPNPHTRITIAQILEDEWFKKDYKPPLS-EHNEDVSLEDVDAAFDSSEEHL-VAERRE 1072 I NP RITI +I WF K ++ E+ + L D++ S EE + + + + Sbjct: 230 IFVGNPQQRITIPEIKNHPWFLKRLPVEMTDEYQRSMQLADMNTPSQSLEEAMAIIQEAQ 289 Query: 1073 KP 1078 KP Sbjct: 290 KP 291
>Q01919:KIN4_YEAST Serine/threonine-protein kinase KIN4 - Saccharomyces cerevisiae| (Baker's yeast) Length = 800 Score = 196 bits (499), Expect = 2e-49 Identities = 118/309 (38%), Positives = 176/309 (56%), Gaps = 14/309 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGAT-----CAIKVLDRNHVLRHKMVE-QIKREIATMK 355 Y +G T+GEG F KVK+ + + AIK++ R+ + + E +I REI +K Sbjct: 46 YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALK 105 Query: 356 LIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDY 535 + HPN++ L EV+ + I +VLEFV GGE + I +L E A R F QLI+ V+Y Sbjct: 106 HLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNY 165 Query: 536 CHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPE-VL 712 H +G+ HRDLK ENLLLD + L ++DFG + +D+ L+ T+CG+P Y APE V+ Sbjct: 166 MHYKGLVHRDLKLENLLLDKHENLVITDFGF--VNEFFEDNELMKTSCGSPCYAAPELVV 223 Query: 713 ADKGYDGMAADVWSCGIILFVLMAGYLPFDD-------PNLMTLYKLISRANVSCPPWFS 871 + K Y+ ADVWSCG+IL+ ++AGYLP+DD ++ LYK I++ + P + + Sbjct: 224 STKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYIT 283 Query: 872 TGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEH 1051 R+L++RIL PNP RI + I W K H +S++ + +EH Sbjct: 284 PIPRDLLRRILVPNPRRRINLQTIKRHVWLK--------PHEAFLSIQP-----NYWDEH 330 Query: 1052 LVAERREKP 1078 L ER + P Sbjct: 331 LQKERPKPP 339
>P22987:KIN1_SCHPO Protein kinase kin1 - Schizosaccharomyces pombe (Fission yeast)| Length = 891 Score = 194 bits (494), Expect = 8e-49 Identities = 106/281 (37%), Positives = 158/281 (56%), Gaps = 18/281 (6%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNH----------------VLRHKMVE 325 Y LGKTIG GS KVKVA + G AIK++ R H + + + Sbjct: 125 YVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNK 184 Query: 326 QIK--REIATMKLIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEAR 499 +I+ RE A L+RHP + + +V + S YMV EFV+GG++ D I++ GKL E +AR Sbjct: 185 EIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQAR 244 Query: 500 RYFHQLINAVDYCHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTAC 679 ++ Q+ +A+ Y H V HRDLK EN+L+ G +K+ DFGLS + L T C Sbjct: 245 KFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNL---YRRQSRLRTFC 301 Query: 680 GTPNYVAPEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP 859 G+ + APE+L + Y G DVWS GI+L+VL+ G +PFDD N+ L+ I + V P Sbjct: 302 GSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYP 361 Query: 860 PWFSTGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPP 982 + S+ + L+ R+L +P R T+ ++L W ++Y+ P Sbjct: 362 SYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWMIRNYEGP 402
>O14757:CHK1_HUMAN Serine/threonine-protein kinase Chk1 - Homo sapiens (Human)| Length = 476 Score = 194 bits (494), Expect = 8e-49 Identities = 141/461 (30%), Positives = 212/461 (45%), Gaps = 44/461 (9%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 ++L +T+GEG++ +V++A + A+K++D + E IK+EI K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAV--DCPENIKKEICINKMLNHEN 66 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 VV+ + + Y+ LE+ GGELFD+I + E +A+R+FHQL+ V Y H G+ Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGI 126 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLLD LK+SDFGL+ + LL+ CGT YVAPE+L + + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHA 186 Query: 734 MAADVWSCGIILFVLMAGYLPFDDP-NLMTLYKLISRANVSCPPW--FSTGARNLIKRIL 904 DVWSCGI+L ++AG LP+D P + Y PW + L+ +IL Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246 Query: 905 DPNPHTRITIAQILEDEWF----KKDYKPP------LSEHNEDVSLE-----DVDAAFDS 1039 NP RITI I +D W+ KK K P +SE S D + Sbjct: 247 VENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDFSPVNSA 306 Query: 1040 SEEHLVAERREKPESMNAFALISRS--------AGFNLGN-------LFEKEMMG----- 1159 S E V +PE +L S G + L +++G Sbjct: 307 SSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLLGTPGSS 366 Query: 1160 ------MVKRETSFASQRTPQEIMSKIEEACGPLGFNVRKQNYKMKLKGDKTGRKGHLSV 1321 +VKR T F ++ + ++E C LG+ +K R L Sbjct: 367 QNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRRNNKLIF 426 Query: 1322 ATEVFEVAPSLHMVELRKTGGDTLEFHSFYQNFSSELKDIV 1444 + E+ + +V+ R + GD LEF + +L DIV Sbjct: 427 KVNLLEMDDKI-LVDFRLSKGDGLEFKRHFLKIKGKLIDIV 466
>Q7XQP4:SAPK7_ORYSJ Serine/threonine-protein kinase SAPK7 - Oryza sativa subsp. japonica| (Rice) Length = 359 Score = 194 bits (493), Expect = 1e-48 Identities = 123/320 (38%), Positives = 170/320 (53%), Gaps = 18/320 (5%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL K IG G+F ++ ++ A+K + R K+ E + REI + +RHPN Sbjct: 4 YELLKDIGAGNFGVARLMRNKETKELVAMKYIPRGL----KIDENVAREIINHRSLRHPN 59 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV+ + + + +V+E+ GGELFD+I N+G+ EDEAR +F QLI V YCH + Sbjct: 60 IIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHFMQI 119 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD A LK+ DFG S S LLH + GTP Y+APEVL+ Sbjct: 120 CHRDLKLENTLLDGSPAPRLKICDFGYSKSS-------LLHSKPKSTVGTPAYIAPEVLS 172 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDDP----NLMTLYKLISRANVSCPPW--FSTG 877 + YDG ADVWSCG+ L+V++ G PF+DP N I P + S Sbjct: 173 RREYDGKTADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYVHVSQD 232 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAA----FDSSE 1045 R L+ RI NP RITI +I WF K+ L+E + + + ++A S E Sbjct: 233 CRQLLSRIFVANPAKRITIREIRNHPWFLKNLPRELTEAAQAMYYKKDNSAPTYSVQSVE 292 Query: 1046 E--HLVAERREKPESMNAFA 1099 E +V E R P S A Sbjct: 293 EIMKIVEEARTPPRSSTPVA 312
>Q5N942:SAPK4_ORYSJ Serine/threonine-protein kinase SAPK4 - Oryza sativa subsp. japonica| (Rice) Length = 360 Score = 194 bits (492), Expect = 1e-48 Identities = 118/315 (37%), Positives = 169/315 (53%), Gaps = 18/315 (5%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE + IG G+F ++ ++ A+K ++R H ++ E + REI + +RHPN Sbjct: 4 YEAVRDIGSGNFGVARLMRNRETRELVAVKCIERGH----RIDENVYREIINHRSLRHPN 59 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV+ + + + +V+EF GGELFD+I + G+ EDEAR +F QLI V YCH + Sbjct: 60 IIRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHHMQI 119 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN+LLD A LK+ DFG S S +LH +A GTP Y+APEVL+ Sbjct: 120 CHRDLKLENVLLDGSPAPRLKICDFGYSKSS-------VLHSRPKSAVGTPAYIAPEVLS 172 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPF---DDP-NLMTLYKLISRANVSCPPW--FSTG 877 + YDG ADVWSCG+ L+V++ G PF DDP N+ + I P + S Sbjct: 173 RREYDGKLADVWSCGVTLYVMLVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYVHISAE 232 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSE------HNEDVSLEDVDAAFDS 1039 + LI RI NP RIT+ +I WF K+ L+E + D S+ Sbjct: 233 CKQLIARIFVNNPLRRITMKEIKSHPWFLKNLPRELTETAQAMYYRRDNSVPSFSDQTSE 292 Query: 1040 SEEHLVAERREKPES 1084 +V E R P+S Sbjct: 293 EIMKIVQEARTMPKS 307
>Q9NRH2:SNRK_HUMAN SNF-related serine/threonine-protein kinase - Homo sapiens (Human)| Length = 765 Score = 192 bits (488), Expect = 4e-48 Identities = 103/271 (38%), Positives = 163/271 (60%), Gaps = 3/271 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L KT+G G FA VK+A+ G A+KV+D+ L + +E+ MKL++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTK-LDTLATGHLFQEVRCMKLVQHPN 74 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGK-LGEDEARRYFHQLINAVDYCHSRG 550 +V+L+EV+ +++K+Y++LE +GG++FD I+ + L ED A++YF Q+++A+ YCH Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134 Query: 551 VYHRDLKPENLLL-DSYGALKVSDFGLS-AFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 V HRDLKPEN++ + G +K++DFG S F P K L T+CG+ Y APE+L Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK----LTTSCGSLAYSAPEILLGDE 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 YD A D+WS G+ILF+L+ G PF + N +I + P S ++LI R+L Sbjct: 191 YDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRML 250 Query: 905 DPNPHTRITIAQILEDEWFKKDYKPPLSEHN 997 +P R ++ +I W + P +++N Sbjct: 251 QRDPKRRASLEEIENHPWLQGVDPSPATKYN 281
>O88866:HUNK_MOUSE Hormonally up-regulated neu tumor-associated kinase - Mus musculus| (Mouse) Length = 714 Score = 192 bits (488), Expect = 4e-48 Identities = 112/279 (40%), Positives = 163/279 (58%), Gaps = 7/279 (2%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMV-EQIKREIATMKLIRHPNVVQ 382 + +GEGSFAKV+ G AIKV+D+ + V + ++RE ++IRHPN+ Q Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 383 LHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHR 562 L +++ +++ Y+V+E GG L KI +L E EARRY QLI+AV++ H GV HR Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHR 185 Query: 563 DLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAA 742 DLK ENLLLD +K+ DFGLS + T CG+P Y APE+LA K Y G Sbjct: 186 DLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKI 244 Query: 743 DVWSCGIILFVLMAGYLPF--DDPNLMTLY-KLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+ ++ ++ G LPF + +L LY K++ +A P STGA N ++ +L+P+ Sbjct: 245 DVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPD 304 Query: 914 PHTRITIAQILEDEWFKKDY--KPPLS-EHNEDVSLEDV 1021 P R I Q L + W ++Y K P + + +SLED+ Sbjct: 305 PVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDL 343
>Q7Y0B9:SAPK8_ORYSJ Serine/threonine-protein kinase SAPK8 - Oryza sativa subsp.| japonica (Rice) Length = 371 Score = 192 bits (487), Expect = 5e-48 Identities = 111/278 (39%), Positives = 157/278 (56%), Gaps = 12/278 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL + IG G+F ++ +D R A+K ++R K+ + ++REI + ++HPN Sbjct: 33 YELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGE----KIDDNVQREIINHRSLKHPN 88 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV+ + + + +V+E+ GGELF++I + + EDEAR +F QLI+ V YCHS V Sbjct: 89 IIRFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYCHSMQV 148 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD A LK+ DFG S S +LH + GTP Y+APEVL Sbjct: 149 CHRDLKLENTLLDGSPAPRLKICDFGYSKSS-------VLHSQPKSTVGTPAYIAPEVLL 201 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDDP----NLMTLYKLISRANVSCPP--WFSTG 877 K YDG ADVWSCG+ L+V++ G PF+DP N + I S P S Sbjct: 202 KKEYDGKTADVWSCGVTLYVMVVGAYPFEDPEEPKNFRKTIQRILNVQYSIPENVDISPE 261 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSE 991 R+LI RI +P RITI +I WF K+ L + Sbjct: 262 CRHLISRIFVGDPSLRITIPEIRSHGWFLKNLPADLMD 299
>P43291:ASK1_ARATH Serine/threonine-protein kinase ASK1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 363 Score = 191 bits (485), Expect = 9e-48 Identities = 110/278 (39%), Positives = 158/278 (56%), Gaps = 12/278 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL K IG G+F ++ K + A+K ++R K+ E + REI + +RHPN Sbjct: 4 YELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGP----KIDENVAREIINHRSLRHPN 59 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV+ + + + + +E+ GGELF++I ++G+ EDEAR +F QLI+ V YCH+ + Sbjct: 60 IIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQI 119 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD A LK+ DFG S S LLH + GTP Y+APEVL+ Sbjct: 120 CHRDLKLENTLLDGSPAPRLKICDFGYSKSS-------LLHSRPKSTVGTPAYIAPEVLS 172 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDD----PNLMTLYKLISRANVSCPPW--FSTG 877 + YDG ADVWSCG+ L+V++ G PF+D N + I P + S Sbjct: 173 RREYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHISQD 232 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSE 991 +NL+ RI N RITIA+I + WF K+ L+E Sbjct: 233 CKNLLSRIFVANSLKRITIAEIKKHSWFLKNLPRELTE 270
>O60285:NUAK1_HUMAN NUAK family SNF1-like kinase 1 - Homo sapiens (Human)| Length = 661 Score = 191 bits (484), Expect = 1e-47 Identities = 116/329 (35%), Positives = 171/329 (51%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL +T+G+G++ KVK A + +G AIK + ++ + + + I+REI M + HP+ Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPH 114 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ ++EV +K KI +++E+ GEL+D I +L E E R +F Q+++AV YCH GV Sbjct: 115 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 174 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK EN+LLD +K++DFGLS + D L T CG+P Y +PE++ + Y G Sbjct: 175 VHRDLKLENILLDDNCNIKIADFGLSNL---YQKDKFLQTFCGSPLYASPEIVNGRPYRG 231 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D W+ G++L+ L+ G +PFD + L + IS P + AR LI+ +L N Sbjct: 232 PEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYR-EPTQPSDARGLIRWMLMVN 290 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREKPESMNA 1093 P R TI I W YK S+ D DA DS E P Sbjct: 291 PDRRATIEDIANHWWVNWGYKS---------SVCDCDALHDS----------ESPLLARI 331 Query: 1094 FALISRSAGFNLGNLFEKEMMGMVKRETS 1180 RS G E +M G+ K TS Sbjct: 332 IDWHHRSTGLQADT--EAKMKGLAKPTTS 358
>Q91ZN7:CHK1_RAT Serine/threonine-protein kinase Chk1 - Rattus norvegicus (Rat)| Length = 476 Score = 191 bits (484), Expect = 1e-47 Identities = 139/461 (30%), Positives = 211/461 (45%), Gaps = 44/461 (9%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 ++L +T+GEG++ +V++A + A+K++D + E IK+EI K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAI--DCPENIKKEICINKMLNHEN 66 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 VV+ + + Y+ LE+ GGELFD+I + E +A+R+FHQL+ V Y H G+ Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGI 126 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLLD LK+SDFGL+ + LL+ CGT YVAPE+L K + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHA 186 Query: 734 MAADVWSCGIILFVLMAGYLPFDDP-NLMTLYKLISRANVSCPPW--FSTGARNLIKRIL 904 DVWSCGI+L ++AG LP+D P + Y PW + L+ +IL Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246 Query: 905 DPNPHTRITIAQILEDEWFKKDY----KPP------LSEHNEDVSLE-----DVDAAFDS 1039 NP RITI I +D W+ K K P +SE + S D Sbjct: 247 VENPSARITIPDIKKDRWYNKPLNRGAKRPRATSGGMSESSSGFSKHIHSNLDFSPINSG 306 Query: 1040 SEEHLVAERREKPESMNAFAL----------ISRSAGFNLGN-----LFEKEMMG----- 1159 S E V +PE +L + + F+ L +++G Sbjct: 307 SSEENVKFSSSQPEPRTGLSLWDTGPSNVDKLVQGISFSQPTCPDHMLVNSQLLGTPGSS 366 Query: 1160 ------MVKRETSFASQRTPQEIMSKIEEACGPLGFNVRKQNYKMKLKGDKTGRKGHLSV 1321 +VKR T F ++ + ++E LG+ +K R L Sbjct: 367 QNPWQRLVKRMTRFFTKLDADKSYQCLKETFEKLGYQWKKSCMNQVTVSTMDRRNNKLIF 426 Query: 1322 ATEVFEVAPSLHMVELRKTGGDTLEFHSFYQNFSSELKDIV 1444 + E+ + +V+ R + GD LEF + +L DIV Sbjct: 427 KINLVEMDEKI-LVDFRLSKGDGLEFKRHFLKIKGKLSDIV 466
>Q6ZI44:SAPK6_ORYSJ Serine/threonine-protein kinase SAPK6 - Oryza sativa subsp.| japonica (Rice) Length = 365 Score = 190 bits (483), Expect = 2e-47 Identities = 111/279 (39%), Positives = 159/279 (56%), Gaps = 13/279 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL K IG G+F ++ ++ A+K + R K+ E + REI + +RHPN Sbjct: 4 YELLKDIGSGNFGVARLMRNRETKELVAMKYIPRGL----KIDENVAREIINHRSLRHPN 59 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV+ + + + +V+E+ GGELFD+I ++G+ EDE+R +F QLI V YCH + Sbjct: 60 IIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHFMQI 119 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD A LK+ DFG S S LLH + GTP Y+APEVL+ Sbjct: 120 CHRDLKLENTLLDGSPAPRLKICDFGYSKSS-------LLHSKPKSTVGTPAYIAPEVLS 172 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDDPN-----LMTLYKLISRANVSCPPW--FST 874 + YDG ADVWSCG+ L+V++ G PF+DP+ T+ +++S P + S Sbjct: 173 RREYDGKMADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIVS-IQYKIPEYVHISQ 231 Query: 875 GARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSE 991 R L+ RI NP RITI +I WF K+ L+E Sbjct: 232 DCRQLLSRIFVANPAKRITIREIRNHPWFMKNLPRELTE 270
>Q5R7G9:NUAK2_PONPY NUAK family SNF1-like kinase 2 - Pongo pygmaeus (Orangutan)| Length = 628 Score = 189 bits (481), Expect = 3e-47 Identities = 102/266 (38%), Positives = 156/266 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE +T+G+G++ KVK A+++ +G AIK + ++ + + + I+REI M + HP+ Sbjct: 53 YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ +HEV + SKI +V+E+ G+L+D I +L E EAR +F Q+++AV YCH V Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK EN+LLD+ G +K++DFGLS Q K L T CG+P Y +PE++ K Y G Sbjct: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGK---FLQTFCGSPLYASPEIVNGKPYTG 228 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D WS G++L++L+ G +PFD + L K IS PP + A LI+ +L N Sbjct: 229 PEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP-KPSDACGLIRWLLMVN 287 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSE 991 P R T+ + W Y + E Sbjct: 288 PTRRATLEDVASHWWVNWGYATRVGE 313
>Q9H093:NUAK2_HUMAN NUAK family SNF1-like kinase 2 - Homo sapiens (Human)| Length = 628 Score = 189 bits (481), Expect = 3e-47 Identities = 102/266 (38%), Positives = 156/266 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE +T+G+G++ KVK A+++ +G AIK + ++ + + + I+REI M + HP+ Sbjct: 53 YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ +HEV + SKI +V+E+ G+L+D I +L E EAR +F Q+++AV YCH V Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK EN+LLD+ G +K++DFGLS Q K L T CG+P Y +PE++ K Y G Sbjct: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGK---FLQTFCGSPLYASPEIVNGKPYTG 228 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D WS G++L++L+ G +PFD + L K IS PP + A LI+ +L N Sbjct: 229 PEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPP-KPSDACGLIRWLLMVN 287 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSE 991 P R T+ + W Y + E Sbjct: 288 PTRRATLEDVASHWWVNWGYATRVGE 313
>Q8IY84:NIM1_HUMAN Serine/threonine-protein kinase NIM1 - Homo sapiens (Human)| Length = 436 Score = 189 bits (481), Expect = 3e-47 Identities = 106/295 (35%), Positives = 165/295 (55%), Gaps = 8/295 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y + IG G+F++VK+ + AIK+LD+ L K + REI++M+ + HPN Sbjct: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTK-LDQKTQRLLSREISSMEKLHHPN 132 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+EV+ + SK+++V+E+ GGELF KI GKL E E++ F Q+++AV + H + Sbjct: 133 IIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQI 192 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK EN+ S +KV DFG FS +K +L+T CG+P Y APE+ D+ Y G Sbjct: 193 IHRDLKAENVFYTSNTCVKVGDFG---FSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIG 249 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 + D+W+ G++L+ ++ G +PF + L K I S PP S LI+ +L Sbjct: 250 IYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQI 309 Query: 914 PHTRITIAQILEDEWFK-KDYKPPLSEH-------NEDVSLEDVDAAFDSSEEHL 1054 P R I I+ DEW + Y PL +E +L++ + S+ EHL Sbjct: 310 PTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHL 364
>Q8BHI9:NIM1_MOUSE Serine/threonine-protein kinase NIM1 - Mus musculus (Mouse)| Length = 436 Score = 189 bits (479), Expect = 5e-47 Identities = 105/295 (35%), Positives = 165/295 (55%), Gaps = 8/295 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y + IG G+F++VK+ + AIK+LD+ L K + REI++M+ + HPN Sbjct: 74 YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTK-LDQKTQRLLSREISSMEKLHHPN 132 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L+EV+ + SK+++V+E+ GGELF KI GKL E E++ F Q+++AV + H + Sbjct: 133 IVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQI 192 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK EN+ S +KV DFG FS +K +L+T CG+P Y APE+ D+ Y G Sbjct: 193 IHRDLKAENVFYTSRTCVKVGDFG---FSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVG 249 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 + D+W+ G++L+ ++ G +PF + L K I + P S LI+ +L P Sbjct: 250 VYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPT 309 Query: 914 PHTRITIAQILEDEWFK-KDYKPPLSEH-------NEDVSLEDVDAAFDSSEEHL 1054 P R I I+ +EW + Y PL +E +L++ + S+ EHL Sbjct: 310 PTERYGINYIMSNEWMRGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHL 364
>Q68UT7:HUNK_PANTR Hormonally up-regulated neu tumor-associated kinase - Pan troglodytes| (Chimpanzee) Length = 714 Score = 189 bits (479), Expect = 5e-47 Identities = 110/279 (39%), Positives = 162/279 (58%), Gaps = 7/279 (2%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMV-EQIKREIATMKLIRHPNVVQ 382 + +GEGSFAKV+ G AIKV+D+ + V + ++RE ++IRHPN+ Q Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 383 LHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHR 562 L +++ +++ Y+V+E GG L KI +L E EARRY QLI+AV++ H GV HR Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHR 185 Query: 563 DLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAA 742 DLK ENLLLD +K+ DFGLS + T CG+P Y APE+LA K Y G Sbjct: 186 DLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKI 244 Query: 743 DVWSCGIILFVLMAGYLPF--DDPNLMTLY-KLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+ ++ ++ G LPF + +L LY K++ + P STGA + ++ +L+P+ Sbjct: 245 DVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPD 304 Query: 914 PHTRITIAQILEDEWFKKDY--KPPLS-EHNEDVSLEDV 1021 P R I Q L + W ++Y K P + + +SLED+ Sbjct: 305 PVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDL 343
>P57058:HUNK_HUMAN Hormonally up-regulated neu tumor-associated kinase - Homo sapiens| (Human) Length = 714 Score = 189 bits (479), Expect = 5e-47 Identities = 110/279 (39%), Positives = 162/279 (58%), Gaps = 7/279 (2%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMV-EQIKREIATMKLIRHPNVVQ 382 + +GEGSFAKV+ G AIKV+D+ + V + ++RE ++IRHPN+ Q Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 383 LHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHR 562 L +++ +++ Y+V+E GG L KI +L E EARRY QLI+AV++ H GV HR Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHR 185 Query: 563 DLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAA 742 DLK ENLLLD +K+ DFGLS + T CG+P Y APE+LA K Y G Sbjct: 186 DLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKI 244 Query: 743 DVWSCGIILFVLMAGYLPF--DDPNLMTLY-KLISRANVSCPPWFSTGARNLIKRILDPN 913 DVWS G+ ++ ++ G LPF + +L LY K++ + P STGA + ++ +L+P+ Sbjct: 245 DVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPD 304 Query: 914 PHTRITIAQILEDEWFKKDY--KPPLS-EHNEDVSLEDV 1021 P R I Q L + W ++Y K P + + +SLED+ Sbjct: 305 PVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDL 343
>Q66HE5:NUAK2_RAT NUAK family SNF1-like kinase 2 - Rattus norvegicus (Rat)| Length = 630 Score = 188 bits (478), Expect = 6e-47 Identities = 99/266 (37%), Positives = 158/266 (59%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE +T+G+G++ KVK A+++ +G AIK + ++ + + + I+REI M + HP+ Sbjct: 57 YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPH 115 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ +HEV + SKI +V+E+ G+L+D I +L E +AR +F Q+++A+ YCH G+ Sbjct: 116 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLNERDARHFFRQIVSALHYCHQNGI 175 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK EN+LLD+ G +K++DFGLS + K L T CG+P Y +PE++ K Y G Sbjct: 176 VHRDLKLENILLDASGNIKIADFGLSNLYHKGK---FLQTFCGSPLYASPEIVNGKPYVG 232 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D WS G++L++L+ G +PFD + TL K IS + P + A LI+ +L N Sbjct: 233 PEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQIS-SGAYREPCKPSDACGLIRWLLMVN 291 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSE 991 P R T+ + W Y + E Sbjct: 292 PIRRATLEDVASHWWVNWGYSTRIGE 317
>O35280:CHK1_MOUSE Serine/threonine-protein kinase Chk1 - Mus musculus (Mouse)| Length = 476 Score = 188 bits (478), Expect = 6e-47 Identities = 137/461 (29%), Positives = 210/461 (45%), Gaps = 44/461 (9%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 ++L +T+GEG++ +V++A + A+K++D + E IK+EI K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAI--DCPENIKKEICINKMLSHEN 66 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 VV+ + Y+ LE+ GGELFD+I + E +A+R+FHQL+ V Y H G+ Sbjct: 67 VVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGI 126 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLLD LK+SDFGL+ + LL+ CGT YVAPE+L K + Sbjct: 127 THRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHA 186 Query: 734 MAADVWSCGIILFVLMAGYLPFDDP-NLMTLYKLISRANVSCPPW--FSTGARNLIKRIL 904 DVWSCGI+L ++AG LP+D P + Y PW + L+ +IL Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246 Query: 905 DPNPHTRITIAQILEDEWFKKDY----KPP------LSEHNEDVSLE-----DVDAAFDS 1039 P RITI I +D W+ K K P +SE + S D + Sbjct: 247 VETPSARITIPDIKKDRWYNKPLNRGAKRPRATSGGMSESSSGFSKHIHSNLDFSPVNNG 306 Query: 1040 SEEHLVAERREKPESMNAFAL----------ISRSAGFNLGN-----LFEKEMMG----- 1159 S E V +PE +L + + F+ L +++G Sbjct: 307 SSEETVKFSSSQPEPRTGLSLWDTGPSNVDKLVQGISFSQPTCPEHMLVNSQLLGTPGSS 366 Query: 1160 ------MVKRETSFASQRTPQEIMSKIEEACGPLGFNVRKQNYKMKLKGDKTGRKGHLSV 1321 +VKR T F ++ + ++E LG+ +K R L Sbjct: 367 QNPWQRLVKRMTRFFTKLDADKSYQCLKETFEKLGYQWKKSCMNQVTVSTTDRRNNKLIF 426 Query: 1322 ATEVFEVAPSLHMVELRKTGGDTLEFHSFYQNFSSELKDIV 1444 + E+ + +V+ R + GD LEF + +L D+V Sbjct: 427 KINLVEMDEKI-LVDFRLSKGDGLEFKRHFLKIKGKLSDVV 466
>Q7XKA8:SAPK5_ORYSJ Serine/threonine-protein kinase SAPK5 - Oryza sativa subsp. japonica| (Rice) Length = 370 Score = 187 bits (476), Expect = 1e-46 Identities = 108/289 (37%), Positives = 160/289 (55%), Gaps = 18/289 (6%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE + IG G+F K+ ++ A+K ++R + ++ E + REI + +RHPN Sbjct: 4 YEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGN----RIDENVFREIVNHRSLRHPN 59 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV+ + + +V+E+ GGELF++I +G+ EDEAR +F QL+ V YCH+ + Sbjct: 60 IIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHAMQI 119 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD A LK+ DFG S S LLH + GTP Y+APEVL+ Sbjct: 120 CHRDLKLENTLLDGSPAPRLKICDFGYSKSS-------LLHSRPKSTVGTPAYIAPEVLS 172 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDDPN------------LMTLYKLISRANVSCP 859 + YDG ADVWSCG+ L+V++ G PF+DP + YK+ +VS P Sbjct: 173 RREYDGKLADVWSCGVTLYVMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYVHVSQP 232 Query: 860 PWFSTGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDV 1006 R+L+ RI NP+ RI++ +I WF K+ L E + V Sbjct: 233 ------CRHLLSRIFVANPYKRISMGEIKSHPWFLKNLPRELKEEAQAV 275
>P07334:CDR1_SCHPO Mitosis inducer protein kinase cdr1 - Schizosaccharomyces pombe| (Fission yeast) Length = 593 Score = 187 bits (476), Expect = 1e-46 Identities = 99/251 (39%), Positives = 149/251 (59%), Gaps = 1/251 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 + LGKT+G GS + V++AK + G AIK++ + I EI M+L+RHPN Sbjct: 12 WRLGKTLGTGSTSCVRLAKHAKTGDLAAIKIIPIRYA-------SIGMEILMMRLLRHPN 64 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L++V +Y+ LE+V GELF I G L E EA Y Q+++AV +CH Sbjct: 65 ILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCHRFRF 124 Query: 554 YHRDLKPENLLLD-SYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYD 730 HRDLK EN+L+ + +K++DFG++ P +D L CG+ +Y+APE+++ K Y Sbjct: 125 RHRDLKLENILIKVNEQQIKIADFGMATVEP---NDSCLENYCGSLHYLAPEIVSHKPYR 181 Query: 731 GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDP 910 G ADVWSCG+IL+ L++ LPF N +Y I P S+ A++L+ R+LD Sbjct: 182 GAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPSSISSAAQDLLHRMLDV 241 Query: 911 NPHTRITIAQI 943 NP TRITI ++ Sbjct: 242 NPSTRITIPEV 252
>P97477:STK6_MOUSE Serine/threonine-protein kinase 6 - Mus musculus (Mouse)| Length = 395 Score = 187 bits (474), Expect = 2e-46 Identities = 89/267 (33%), Positives = 156/267 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++G+ +G+G F V +A++ ++ A+KVL + + + + Q++RE+ +RHPN Sbjct: 124 FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPN 183 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ +++Y++LE+ G ++ ++ K E Y +L NA+ YCHS+ V Sbjct: 184 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 243 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL S G LK++DFG S +P ++ T CGT +Y+ PE++ + +D Sbjct: 244 IHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TMCGTLDYLPPEMIEGRMHD- 298 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++ + + G PF+ Y+ ISR + P + + GAR+LI R+L N Sbjct: 299 EKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHN 358 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEH 994 R+T+A++LE W K + P + H Sbjct: 359 ASQRLTLAEVLEHPWIKANSSKPPTGH 385
>O13945:PPK9_SCHPO Protein kinase domain-containing protein ppk9 - Schizosaccharomyces| pombe (Fission yeast) Length = 532 Score = 187 bits (474), Expect = 2e-46 Identities = 90/257 (35%), Positives = 156/257 (60%) Frame = +2 Query: 200 LGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVV 379 LG+T+G+G+ AKVK+ K + A+K++ + + ++++RE+ ++ + HPN++ Sbjct: 25 LGRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKRLQREVTILRQLHHPNII 84 Query: 380 QLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYH 559 L++V + LE+++ +L +V +L E R+ F Q+++A+DYCH V H Sbjct: 85 TLYQVFRVPKYTVLALEYMDT-DLHSMVVKHNRLDECTTRKIFRQIVHAIDYCHLHRVAH 143 Query: 560 RDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMA 739 RDLK EN+LL+ +K++DFGLS F D L T+CGTP+Y APEV+ + YDG Sbjct: 144 RDLKLENILLNKDLVVKLTDFGLSNFM---LDGSFLSTSCGTPHYAAPEVIQGRYYDGCD 200 Query: 740 ADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPNPH 919 DVW CGI+L++++ G PF+D + + + + + P + S+ A +LI+++L P Sbjct: 201 VDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCKGIYTIPSFVSSSASDLIRQMLMVLPT 260 Query: 920 TRITIAQILEDEWFKKD 970 +RI +A+I++ WF D Sbjct: 261 SRIKVAEIMQHPWFIAD 277
>Q641K5:NUAK1_MOUSE NUAK family SNF1-like kinase 1 - Mus musculus (Mouse)| Length = 658 Score = 187 bits (474), Expect = 2e-46 Identities = 99/261 (37%), Positives = 150/261 (57%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL +T+G+G++ KVK A + +G AIK + ++ + + I+REI M + HP+ Sbjct: 56 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHPH 115 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ ++EV +K KI +++E+ GEL+D I +L E E R +F Q+++AV YCH GV Sbjct: 116 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 175 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK EN+LLD +K++DFGLS + D L T CG+P Y +PE++ + Y G Sbjct: 176 VHRDLKLENILLDDNCNIKIADFGLSNL---YQKDKFLQTFCGSPLYASPEIVNGRPYRG 232 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D W+ G++L+ L+ G +PFD + L + IS P + AR LI+ +L N Sbjct: 233 PEVDSWALGVLLYTLIYGTMPFDGFDHKNLIRQISSGEYR-EPTQPSDARGLIRWMLMVN 291 Query: 914 PHTRITIAQILEDEWFKKDYK 976 P R TI I W YK Sbjct: 292 PDRRATIEDIANHWWVNWGYK 312
>Q8BW96:KCC1D_MOUSE Calcium/calmodulin-dependent protein kinase type 1D - Mus musculus| (Mouse) Length = 385 Score = 187 bits (474), Expect = 2e-46 Identities = 125/381 (32%), Positives = 194/381 (50%), Gaps = 10/381 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E +T+G G+F++V +A++ G A+K + + L+ K I+ EIA ++ I+H N Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKK-ALKGKE-SSIENEIAVLRKIKHEN 80 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L ++ S + +Y+V++ V GGELFD+IV G E +A Q+++AV Y H G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 554 YHRDLKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLL D + +SDFGLS + K D ++ TACGTP YVAPEVLA K Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSKM--EGKGD-VMSTACGTPGYVAPEVLAQKP 197 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y A D WS G+I ++L+ GY PF D N L++ I +A P W S A++ I Sbjct: 198 Y-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256 Query: 893 KRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERRE 1072 + +++ +P+ R T Q W D LS++ + + F S+ Sbjct: 257 RNLMEKDPNKRYTCEQAARHPWIAGD--TALSKNIHESVSAQIRKNFAKSKWR------- 307 Query: 1073 KPESMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQR---TPQEIMSKIEEACGPL 1243 ++ NA A++ LG+ + V S ASQ+ P + S + + G Sbjct: 308 --QAFNATAVVRHMRRLQLGSSLDSS-NASVSSNLSLASQKDCLAPSTLCSFLSSSSGVA 364 Query: 1244 GFNVRKQNYKMKLKGDKTGRK 1306 G ++ + TG K Sbjct: 365 GVGAERRPRPTTVTTGHTGSK 385
>Q8AYC9:CHK1_CHICK Serine/threonine-protein kinase Chk1 - Gallus gallus (Chicken)| Length = 476 Score = 187 bits (474), Expect = 2e-46 Identities = 138/464 (29%), Positives = 211/464 (45%), Gaps = 47/464 (10%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 ++L +T+GEG++ +V++A + R A+K++D E IK+EI K++ H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAA--DCPENIKKEICINKMLNHEN 66 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 VV+ + + Y+ LE+ GGELFD+I + E EA+R+F QLI V Y HS G+ Sbjct: 67 VVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHSMGI 126 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLLLD LK+SDFGL+ + LL+ CGT YVAPE+L + Sbjct: 127 THRDLKPENLLLDERDNLKISDFGLATVFKHNGRERLLNKMCGTLPYVAPELLRRPEFRA 186 Query: 734 MAADVWSCGIILFVLMAGYLPFDDP-NLMTLYKLISRANVSCPPW--FSTGARNLIKRIL 904 DVW+CG++L ++AG LP+D P + Y PW + L+ +IL Sbjct: 187 EPVDVWACGVVLTAMLAGELPWDQPSDSCQEYSDWKERKTYLAPWRKIDSAPLALLHKIL 246 Query: 905 DPNPHTRITIAQILEDEWFKKDYKP-----------------PLSEH-NEDVSLEDVDAA 1030 NP RITI I +D W+ + K L +H D V +A Sbjct: 247 TENPTARITIPDIKKDRWYCRPLKKGTKRGRVSSGGVTESPGALPKHIRSDTDFSPVKSA 306 Query: 1031 FDSSEEHLVAERREKPESMNAFALISRSAG----------FNL-----GNLFEKEMMG-- 1159 E + +PE AL S G F+ L +++G Sbjct: 307 LG---EDKASYSTSQPEPGTGGALWDSSTGSIDRLVQGISFSQPACPEHMLLNSQLLGTP 363 Query: 1160 ---------MVKRETSFASQRTPQEIMSKIEEACGPLGFNVRKQNYKMKLKGDKTGRKGH 1312 +V+R T F ++ + + C +G+ KQ+ ++ T R+ + Sbjct: 364 GSSQSPWQRLVRRMTRFFTKLDADGSYRSLRDVCEKMGYG-WKQSCTNQVTISTTDRRNN 422 Query: 1313 LSVATEVFEVAPSLHMVELRKTGGDTLEFHSFYQNFSSELKDIV 1444 + S +V+ R + GD LEF + +L D+V Sbjct: 423 KLIFKVNLLEMESRILVDFRLSKGDGLEFKRHFLKIKGKLSDVV 466
>P59241:STK6_RAT Serine/threonine-protein kinase 6 - Rattus norvegicus (Rat)| Length = 397 Score = 186 bits (472), Expect = 3e-46 Identities = 90/268 (33%), Positives = 156/268 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++G+ +G+G F V +A++ ++ A+KVL + + + + Q++RE+ +RHPN Sbjct: 126 FDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQLRREVEIQSHLRHPN 185 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ +++Y++LE+ G ++ ++ K E Y +L NA+ YCHS+ V Sbjct: 186 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 245 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL S G LK++DFG S +P ++ T CGT +Y PE++ + +D Sbjct: 246 IHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYQPPEMIEGRMHD- 300 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++ + + G PF+ Y+ ISR + P + + GAR+LI R+L N Sbjct: 301 EKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHN 360 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEHN 997 R+T+A++LE W K + P + HN Sbjct: 361 SSQRLTLAEVLEHPWIKANSSKPPTGHN 388
>Q8IU85:KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D - Homo sapiens| (Human) Length = 385 Score = 186 bits (471), Expect = 4e-46 Identities = 125/367 (34%), Positives = 192/367 (52%), Gaps = 10/367 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E +T+G G+F++V +A++ G A+K + + L+ K I+ EIA ++ I+H N Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKK-ALKGKE-SSIENEIAVLRKIKHEN 80 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L ++ S + +Y+V++ V GGELFD+IV G E +A Q+++AV Y H G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 554 YHRDLKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLL D + +SDFGLS + K D ++ TACGTP YVAPEVLA K Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSKM--EGKGD-VMSTACGTPGYVAPEVLAQKP 197 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y A D WS G+I ++L+ GY PF D N L++ I +A P W S A++ I Sbjct: 198 Y-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256 Query: 893 KRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERRE 1072 + +++ +P+ R T Q W D + H E VS + + F S+ Sbjct: 257 RNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIH-ESVSAQ-IRKNFAKSKWR------- 307 Query: 1073 KPESMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQR---TPQEIMSKIEEACGPL 1243 ++ NA A++ +LG+ + V S ASQ+ P + S I + G Sbjct: 308 --QAFNATAVVRHMRKLHLGSSLDSS-NASVSSSLSLASQKDCLAPSTLCSFISSSSGVS 364 Query: 1244 GFNVRKQ 1264 G ++ Sbjct: 365 GVGAERR 371
>Q63450:KCC1A_RAT Calcium/calmodulin-dependent protein kinase type 1 - Rattus| norvegicus (Rat) Length = 374 Score = 186 bits (471), Expect = 4e-46 Identities = 106/267 (39%), Positives = 155/267 (58%), Gaps = 8/267 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+ +G G+F++V +A+D R AIK + + + + ++ EIA + I+HPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGKE--GSMENEIAVLHKIKHPN 77 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L ++ S +Y++++ V GGELFD+IV G E +A R Q+++AV Y H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 554 YHRDLKPENLL---LDSYGALKVSDFGLSAFSPQTKDDG-LLHTACGTPNYVAPEVLADK 721 HRDLKPENLL LD + +SDFGLS + +D G +L TACGTP YVAPEVLA K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLS----KMEDPGSVLSTACGTPGYVAPEVLAQK 193 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNL 889 Y A D WS G+I ++L+ GY PF D N L++ I +A P W S A++ Sbjct: 194 PY-SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDF 252 Query: 890 IKRILDPNPHTRITIAQILEDEWFKKD 970 I+ +++ +P R T Q L+ W D Sbjct: 253 IRHLMEKDPEKRFTCEQALQHPWIAGD 279
>Q91YS8:KCC1A_MOUSE Calcium/calmodulin-dependent protein kinase type 1 - Mus musculus| (Mouse) Length = 374 Score = 186 bits (471), Expect = 4e-46 Identities = 106/267 (39%), Positives = 155/267 (58%), Gaps = 8/267 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+ +G G+F++V +A+D R AIK + + + + ++ EIA + I+HPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGKE--GSMENEIAVLHKIKHPN 77 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L ++ S +Y++++ V GGELFD+IV G E +A R Q+++AV Y H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 554 YHRDLKPENLL---LDSYGALKVSDFGLSAFSPQTKDDG-LLHTACGTPNYVAPEVLADK 721 HRDLKPENLL LD + +SDFGLS + +D G +L TACGTP YVAPEVLA K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLS----KMEDPGSVLSTACGTPGYVAPEVLAQK 193 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNL 889 Y A D WS G+I ++L+ GY PF D N L++ I +A P W S A++ Sbjct: 194 PY-SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDF 252 Query: 890 IKRILDPNPHTRITIAQILEDEWFKKD 970 I+ +++ +P R T Q L+ W D Sbjct: 253 IRHLMEKDPEKRFTCEQALQHPWIAGD 279
>Q14012:KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 - Homo sapiens| (Human) Length = 370 Score = 186 bits (471), Expect = 4e-46 Identities = 106/267 (39%), Positives = 155/267 (58%), Gaps = 8/267 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+ +G G+F++V +A+D R AIK + + + + ++ EIA + I+HPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKE--GSMENEIAVLHKIKHPN 77 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L ++ S +Y++++ V GGELFD+IV G E +A R Q+++AV Y H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 554 YHRDLKPENLL---LDSYGALKVSDFGLSAFSPQTKDDG-LLHTACGTPNYVAPEVLADK 721 HRDLKPENLL LD + +SDFGLS + +D G +L TACGTP YVAPEVLA K Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLS----KMEDPGSVLSTACGTPGYVAPEVLAQK 193 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNL 889 Y A D WS G+I ++L+ GY PF D N L++ I +A P W S A++ Sbjct: 194 PY-SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDF 252 Query: 890 IKRILDPNPHTRITIAQILEDEWFKKD 970 I+ +++ +P R T Q L+ W D Sbjct: 253 IRHLMEKDPEKRFTCEQALQHPWIAGD 279
>Q9C098:DCLK3_HUMAN Serine/threonine-protein kinase DCLK3 - Homo sapiens (Human)| Length = 648 Score = 185 bits (469), Expect = 7e-46 Identities = 106/309 (34%), Positives = 175/309 (56%), Gaps = 10/309 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE G+ IG+G+FA VK + A+K++D++ + + + + EI ++ + HPN Sbjct: 356 YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKE--DMVDSEILIIQSLSHPN 413 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LHEV + +IY++LE+V+GG+LFD I+ S K E +A L A+ + H + + Sbjct: 414 IVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSI 473 Query: 554 YHRDLKPENLLL----DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 HRDLKPENLL+ D LK++DFGL+ + + T CGTP YVAPE+L++K Sbjct: 474 VHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRP-----IFTVCGTPTYVAPEILSEK 528 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDP--NLMTLYKLISRANVS-CPPWF---STGAR 883 GY G+ D+W+ G+IL++L+ G+ PF P + L+ +I + PP++ S A+ Sbjct: 529 GY-GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAK 587 Query: 884 NLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAE 1063 +L+ R+L +P R T Q+L+ W + K + + VS SSE H ++ Sbjct: 588 DLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKRQKQVS--------PSSEGHFRSQ 639 Query: 1064 RREKPESMN 1090 + E ++ Sbjct: 640 HKRVVEQVS 648
>P43292:ASK2_ARATH Serine/threonine-protein kinase ASK2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 353 Score = 184 bits (467), Expect = 1e-45 Identities = 117/342 (34%), Positives = 179/342 (52%), Gaps = 15/342 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ K +G G+F ++ + A+K ++R K+ E + REI + ++HPN Sbjct: 4 YDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGR----KIDENVAREIINHRSLKHPN 59 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ EV+ + + + +V+E+ GGELFD+I +G+ E EAR +F QLI VDYCHS + Sbjct: 60 IIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSLQI 119 Query: 554 YHRDLKPENLLLDSYGA--LKVSDFGLSAFSPQTKDDGLLH----TACGTPNYVAPEVLA 715 HRDLK EN LLD A LK+ DFG S S +LH + GTP Y+APEVL+ Sbjct: 120 CHRDLKLENTLLDGSPAPLLKICDFGYSKSS-------ILHSRPKSTVGTPAYIAPEVLS 172 Query: 716 DKGYDGMAADVWSCGIILFVLMAGYLPFDDP----NLMTLYKLISRANVSCPPW--FSTG 877 + YDG ADVWSCG+ L+V++ G PF+DP N + I P + S Sbjct: 173 RREYDGKHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQE 232 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLE-DVDAAFDSSEE-- 1048 ++L+ RI N RIT+ +I W+ K+ L E + + D + S E+ Sbjct: 233 CKHLLSRIFVTNSAKRITLKEIKNHPWYLKNLPKELLESAQAAYYKRDTSFSLQSVEDIM 292 Query: 1049 HLVAERREKPESMNAFALISRSAGFNLGNLFEKEMMGMVKRE 1174 +V E R S +A +S+G E+++ V+ E Sbjct: 293 KIVGEARNPAPSTSAV----KSSGSGADEEEEEDVEAEVEEE 330
>Q2TA06:STK6_BOVIN Serine/threonine-protein kinase 6 - Bos taurus (Bovine)| Length = 402 Score = 184 bits (466), Expect = 1e-45 Identities = 91/272 (33%), Positives = 154/272 (56%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A++ ++ A+KVL + + + + Q++RE+ +RHPN Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ +++Y++LE+ G ++ ++ K E Y +L NA+ YCHS+ V Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL S G LK++DFG S +P ++ T CGT +Y+ PE++ + +D Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD- 307 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++ + + G PF+ Y+ ISR + P GAR+LI R+L N Sbjct: 308 EKVDLWSLGVLCYEFLVGKPPFEADTYQETYRRISRVEFTFPDCVPEGARDLISRLLKHN 367 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEHNEDVS 1009 P R T+ ++LE W + KP + E S Sbjct: 368 PSQRPTLKEVLEHPWIIANSKPSSCQKKESTS 399
>Q91819:STK6L_XENLA Serine/threonine-protein kinase Eg2-like - Xenopus laevis (African| clawed frog) Length = 408 Score = 184 bits (466), Expect = 1e-45 Identities = 87/263 (33%), Positives = 155/263 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A++ + A+KVL ++ + + + Q++RE+ +RHPN Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPN 199 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ S++Y++L++ GGELF ++ + + + Y QL A+ YCHS+ V Sbjct: 200 ILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHSKKV 259 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL S G LK++DFG S +P ++ T CGT +Y+ PE++ + +D Sbjct: 260 IHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD- 314 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++ + + G PF+ Y+ IS+ PP+ S A++L+ ++L N Sbjct: 315 EKVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEAKDLVSKLLKHN 374 Query: 914 PHTRITIAQILEDEWFKKDYKPP 982 P+ R+ + +LE W K+ + P Sbjct: 375 PNHRLPLKGVLEHPWIVKNSQQP 397
>Q8BZN4:NUAK2_MOUSE NUAK family SNF1-like kinase 2 - Mus musculus (Mouse)| Length = 639 Score = 184 bits (466), Expect = 1e-45 Identities = 101/274 (36%), Positives = 159/274 (58%), Gaps = 8/274 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE +T+G+G++ KVK A+++ +G AIK + ++ + + + I+REI M + HP+ Sbjct: 57 YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPH 115 Query: 374 VVQLHEVMASK--------SKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAV 529 ++ +HEV S+ SKI +V+E+ G+L+D I +L E +AR +F Q+++A+ Sbjct: 116 IIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSAL 175 Query: 530 DYCHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEV 709 YCH G+ HRDLK EN+LLD+ G +K++DFGLS + K L T CG+P Y +PE+ Sbjct: 176 HYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGK---FLQTFCGSPLYASPEI 232 Query: 710 LADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNL 889 + K Y G D WS G++L++L+ G +PFD + TL K IS PP + A L Sbjct: 233 VNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTLVKQISNGAYREPP-KPSDACGL 291 Query: 890 IKRILDPNPHTRITIAQILEDEWFKKDYKPPLSE 991 I+ +L NP R T+ + W Y + E Sbjct: 292 IRWLLMVNPTRRATLEDVASHWWVNWGYTTGVGE 325
>Q91820:STK6_XENLA Serine/threonine-protein kinase 6 - Xenopus laevis (African clawed| frog) Length = 407 Score = 183 bits (465), Expect = 2e-45 Identities = 87/259 (33%), Positives = 153/259 (59%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A++ + A+KVL ++ + + + Q++RE+ +RHPN Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPN 199 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ S++Y++L++ GGELF ++ + + + Y QL A+ YCHS+ V Sbjct: 200 ILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHSKKV 259 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL S G LK++DFG S +P ++ T CGT +Y+ PE++ + +D Sbjct: 260 IHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD- 314 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++ + + G PF+ Y+ IS+ PP+ S AR+L+ ++L N Sbjct: 315 ETVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEARDLVSKLLKHN 374 Query: 914 PHTRITIAQILEDEWFKKD 970 P+ R+ + +LE W K+ Sbjct: 375 PNHRLPLKGVLEHPWIIKN 393
>P06244:KAPA_YEAST cAMP-dependent protein kinase type 1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 397 Score = 183 bits (465), Expect = 2e-45 Identities = 95/293 (32%), Positives = 165/293 (56%), Gaps = 18/293 (6%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++ +T+G GSF +V + + NG A+KVL + V+R K VE E + ++ HP Sbjct: 87 FQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPF 146 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++++ +I+M+++++EGGELF + S + A+ Y ++ A++Y HS+ + Sbjct: 147 IIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDI 206 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPEN+LLD G +K++DFG + + P + +T CGTP+Y+APEV++ K Y+ Sbjct: 207 IYRDLKPENILLDKNGHIKITDFGFAKYVPD-----VTYTLCGTPDYIAPEVVSTKPYN- 260 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 + D WS GI+++ ++AGY PF D N M Y+ I A + PP+F+ ++L+ R++ + Sbjct: 261 KSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRD 320 Query: 914 PHTRITIAQ-----ILEDEWFKK-------------DYKPPLSEHNEDVSLED 1018 R+ Q + WFK+ Y+PP+ + D S D Sbjct: 321 LSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFD 373
>O08875:DCLK1_RAT Serine/threonine-protein kinase DCLK1 - Rattus norvegicus (Rat)| Length = 433 Score = 182 bits (463), Expect = 3e-45 Identities = 102/282 (36%), Positives = 164/282 (58%), Gaps = 10/282 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++G+TIG+G+FA VK + A+K++ ++ + I+ E++ ++ ++HPN Sbjct: 83 YKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKE--HMIQNEVSILRRVKHPN 140 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L E M +++Y+V+E V+GG+LFD I ++ K E +A + L +A+ Y HS + Sbjct: 141 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNI 200 Query: 554 YHRDLKPENLLL----DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 HRD+KPENLL+ D +LK+ DFGL+ T DG L+T CGTP YVAPE++A+ Sbjct: 201 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA-----TIVDGPLYTVCGTPTYVAPEIIAET 255 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPF----DDPNLMTLYKLISRANVSCPPW--FSTGAR 883 GY G+ D+W+ G+I ++L+ G+ PF DD ++ L+ + + P W S A+ Sbjct: 256 GY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAK 314 Query: 884 NLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVS 1009 LI +L N R + Q+LE W D P +EH V+ Sbjct: 315 ELINMMLLVNVDQRFSAVQVLEHPWVNDDGLPE-NEHQLSVA 355
>Q9JLM8:DCLK1_MOUSE Serine/threonine-protein kinase DCLK1 - Mus musculus (Mouse)| Length = 756 Score = 182 bits (463), Expect = 3e-45 Identities = 102/282 (36%), Positives = 164/282 (58%), Gaps = 10/282 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++G+TIG+G+FA VK + A+K++ ++ + I+ E++ ++ ++HPN Sbjct: 406 YKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKE--HMIQNEVSILRRVKHPN 463 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L E M +++Y+V+E V+GG+LFD I ++ K E +A + L +A+ Y HS + Sbjct: 464 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNI 523 Query: 554 YHRDLKPENLLL----DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 HRD+KPENLL+ D +LK+ DFGL+ T DG L+T CGTP YVAPE++A+ Sbjct: 524 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA-----TIVDGPLYTVCGTPTYVAPEIIAET 578 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPF----DDPNLMTLYKLISRANVSCPPW--FSTGAR 883 GY G+ D+W+ G+I ++L+ G+ PF DD ++ L+ + + P W S A+ Sbjct: 579 GY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAK 637 Query: 884 NLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVS 1009 LI +L N R + Q+LE W D P +EH V+ Sbjct: 638 ELINMMLLVNVDQRFSAVQVLEHPWVNDDGLPE-NEHQLSVA 678
>Q6GPL3:AUKBB_XENLA Serine/threonine-protein kinase 12-B - Xenopus laevis (African| clawed frog) Length = 368 Score = 182 bits (462), Expect = 4e-45 Identities = 85/267 (31%), Positives = 157/267 (58%), Gaps = 3/267 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++G+ +G+G F V +A++ +N A+KVL ++ + + + Q++REI +RHPN Sbjct: 100 FDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPN 159 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++++ + +IY++LEF GEL+ ++ G+ E + + +L +A+ YCH R V Sbjct: 160 ILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALQYCHERKV 219 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLL+ G LK++DFG S +P + T CGT +Y+ PE++ K +D Sbjct: 220 IHRDIKPENLLMGYKGELKIADFGWSVHAPSLR----RRTMCGTLDYLPPEMIEGKTHD- 274 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+W G++ + + G PFD P+ ++ I ++ PP+ S G+++LI ++L + Sbjct: 275 EKVDLWCAGVLCYEFLVGMPPFDSPSHSETHRRIVNVDLKFPPFLSEGSKDLISKLLRYH 334 Query: 914 PHTRITIAQILEDEWFKKDYK---PPL 985 P R+ + ++E W K + + PP+ Sbjct: 335 PAQRLPLKGVMEHPWVKANSRRVLPPV 361
>Q6DE08:AUKBA_XENLA Serine/threonine-protein kinase 12-A - Xenopus laevis (African clawed| frog) Length = 361 Score = 182 bits (462), Expect = 4e-45 Identities = 85/272 (31%), Positives = 159/272 (58%), Gaps = 3/272 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++G+ +G+G F V +A++ +N A+KVL ++ + + + Q++REI +RHPN Sbjct: 93 FDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPN 152 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++++ + +IY++LEF GEL+ ++ G+ E + + +L +A+ YCH R V Sbjct: 153 ILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALHYCHERKV 212 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLL+ G LK++DFG S +P + T CGT +Y+ PE++ K +D Sbjct: 213 IHRDIKPENLLMGYKGELKIADFGWSVHAPSLR----RRTMCGTLDYLPPEMIEGKTHD- 267 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+W G++ + + G PFD P+ ++ I ++ PP+ S G+++LI ++L + Sbjct: 268 EKVDLWCAGVLCYEFLVGMPPFDSPSHTETHRRIVNVDLKFPPFLSDGSKDLISKLLRYH 327 Query: 914 PHTRITIAQILEDEWFKKDYK---PPLSEHNE 1000 P R+ + ++E W K + + PP+ + + Sbjct: 328 PPQRLPLKGVMEHPWVKANSRRVLPPVYQSTQ 359
>Q9D2E1:TSSK3_MOUSE Testis-specific serine/threonine-protein kinase 3 - Mus musculus| (Mouse) Length = 268 Score = 182 bits (461), Expect = 6e-45 Identities = 98/258 (37%), Positives = 157/258 (60%), Gaps = 3/258 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+LGKTIGEG+++KVK A ++ AIK++D+ + + RE+ ++ + H N Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 374 VVQLHEVMASKS-KIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 ++Q++E++ S KIY+V+E EGG++FD ++N G L E A+ F Q++ A+ YCH G Sbjct: 70 IIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129 Query: 551 VYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYD 730 V HRDLK EN LL + LK++DFG + P+++ + L T CG+ Y APEVL +D Sbjct: 130 VAHRDLKCENALLQGFN-LKLTDFGFAKVLPKSRRE-LSQTFCGSTAYAAPEVLQGIPHD 187 Query: 731 GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPP--WFSTGARNLIKRIL 904 DVWS G++L+V++ LPFDD ++ + + VS P ST ++L+KR+L Sbjct: 188 SKKGDVWSMGVVLYVMLCASLPFDDTDIPKML-WQQQKGVSFPTHLGISTECQDLLKRLL 246 Query: 905 DPNPHTRITIAQILEDEW 958 +P+ R +I ++ W Sbjct: 247 EPDMILRPSIEEVSWHPW 264
>O14965:STK6_HUMAN Serine/threonine-protein kinase 6 - Homo sapiens (Human)| Length = 403 Score = 182 bits (461), Expect = 6e-45 Identities = 89/270 (32%), Positives = 155/270 (57%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A++ ++ A+KVL + + + + Q++RE+ +RHPN Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ +++Y++LE+ G ++ ++ K E Y +L NA+ YCHS+ V Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL S G LK++DFG S +P ++ T CGT +Y+ PE++ + +D Sbjct: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD- 307 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++ + + G PF+ YK ISR + P + + GAR+LI R+L N Sbjct: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367 Query: 914 PHTRITIAQILEDEWFKKDYKPPLSEHNED 1003 P R + ++LE W + P + N++ Sbjct: 368 PSQRPMLREVLEHPWITANSSKPSNCQNKE 397
>O70150:KCC1B_RAT Calcium/calmodulin-dependent protein kinase type 1B - Rattus| norvegicus (Rat) Length = 343 Score = 182 bits (461), Expect = 6e-45 Identities = 106/266 (39%), Positives = 155/266 (58%), Gaps = 7/266 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+ + +G G+F++V +A++ + A+K + + LR K ++ EIA ++ I HPN Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKK-ALRGKEA-LVENEIAVLRRISHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L +V S S +Y+ +E V GGELFD+I+ G E +A Q++ AV Y HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 554 YHRDLKPENLLLDS---YGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLL + + VSDFGLS + + +L TACGTP YVAPE+L K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLS----KIQAGNMLGTACGTPGYVAPELLEQKP 188 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRAN--VSCPPW--FSTGARNLI 892 Y G A DVW+ G+I ++L+ GY PF D + L+ I RA+ P W S A++ I Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 893 KRILDPNPHTRITIAQILEDEWFKKD 970 + +L+ +P R T Q L+ W D Sbjct: 248 RHLLERDPQKRFTCQQALQHLWISGD 273
>Q9QYK9:KCC1B_MOUSE Calcium/calmodulin-dependent protein kinase type 1B - Mus musculus| (Mouse) Length = 343 Score = 182 bits (461), Expect = 6e-45 Identities = 106/266 (39%), Positives = 155/266 (58%), Gaps = 7/266 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+ + +G G+F++V +A++ + A+K + + LR K ++ EIA ++ I HPN Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKK-ALRGKEA-LVENEIAVLRRISHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L +V S S +Y+ +E V GGELFD+I+ G E +A Q++ AV Y HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 554 YHRDLKPENLLLDS---YGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLL + + VSDFGLS + + +L TACGTP YVAPE+L K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLS----KIQAGNMLGTACGTPGYVAPELLEQKP 188 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRAN--VSCPPW--FSTGARNLI 892 Y G A DVW+ G+I ++L+ GY PF D + L+ I RA+ P W S A++ I Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 893 KRILDPNPHTRITIAQILEDEWFKKD 970 + +L+ +P R T Q L+ W D Sbjct: 248 RHLLERDPQKRFTCQQALQHLWISGD 273
>Q03002:YP141_YEAST Putative serine/threonine-protein kinase YPL141C - Saccharomyces| cerevisiae (Baker's yeast) Length = 865 Score = 181 bits (460), Expect = 7e-45 Identities = 111/277 (40%), Positives = 163/277 (58%), Gaps = 20/277 (7%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVA--KDTRNGATC--------AIKVLDRNHVLRHKMVE-QIKRE 340 Y LG T+GEG F KVK+ K+ N + AIK++ R+ + E +I RE Sbjct: 41 YILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYRE 100 Query: 341 IATMKLIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLI 520 I +K + HPN+V+L EV+ + I +VLE+ GGE + I +L E A R F QLI Sbjct: 101 INALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLI 160 Query: 521 NAVDYCHSRGVYHRDLKPENLLLDSYGALKVSDFG-LSAFSPQTKDDGLLHTACGTPNYV 697 + V Y HS+G+ HRDLK ENLLLD L ++DFG ++ F + + L+ T+CG+P Y Sbjct: 161 SGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNE---LMKTSCGSPCYA 217 Query: 698 APE-VLADKGYDGMAADVWSCGIILFVLMAGYLPF-DDPN------LMTLYKLISRANVS 853 APE V++ + Y+ AD+WSCG+IL+ ++AGYLP+ DDPN + LY I+ + Sbjct: 218 APELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLK 277 Query: 854 CPPWFSTGARNLIKRILDPNPHTRITIAQILEDEWFK 964 P + R+L++R+L +P RI + QI + EW K Sbjct: 278 FPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLK 314
>Q8N568:DCLK2_HUMAN Serine/threonine-protein kinase DCLK2 - Homo sapiens (Human)| Length = 766 Score = 181 bits (459), Expect = 9e-45 Identities = 98/269 (36%), Positives = 156/269 (57%), Gaps = 10/269 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++GK IG+G+FA VK D G A+K++D+ + + I+ E++ ++ ++HPN Sbjct: 394 YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHL--IENEVSILRRVKHPN 451 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ L E M + +++++V+E V+GG+LFD I +S K E + + L NA+ Y H + Sbjct: 452 IIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSI 511 Query: 554 YHRDLKPENLLL----DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 HRD+KPENLL+ D +LK+ DFGL+ T +G L+T CGTP YVAPE++A+ Sbjct: 512 VHRDIKPENLLVCEYPDGTKSLKLGDFGLA-----TVVEGPLYTVCGTPTYVAPEIIAET 566 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLM--TLYK--LISRANVSCPPW--FSTGAR 883 GY G+ D+W+ G+I ++L+ G+ PF N + L+ L + P W + A+ Sbjct: 567 GY-GLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAK 625 Query: 884 NLIKRILDPNPHTRITIAQILEDEWFKKD 970 LI ++L N R T QIL W D Sbjct: 626 ELISQMLQVNVEARCTAGQILSHPWVSDD 654
>O59790:ARK1_SCHPO Serine/threonine-protein kinase ark1 - Schizosaccharomyces pombe| (Fission yeast) Length = 355 Score = 181 bits (459), Expect = 9e-45 Identities = 91/273 (33%), Positives = 159/273 (58%), Gaps = 1/273 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+GK +G+G F +V +AK+ + G A+K L ++ +++ K+ +Q++REI +RH N Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ + +IY++LEF GEL+ + + + E+ A +Y Q+ NA+ Y H + V Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 208 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPEN+LL G +K+SDFG S +P + T CGT +Y+ PE++ K + Sbjct: 209 IHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRT----TLCGTLDYLPPEMVEGKEHT- 263 Query: 734 MAADVWSCGIILFVLMAGYLPFDD-PNLMTLYKLISRANVSCPPWFSTGARNLIKRILDP 910 D+WS G++ + + G PF+D YK I++ ++ P + AR+LI R+L Sbjct: 264 EKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLISRLLQH 323 Query: 911 NPHTRITIAQILEDEWFKKDYKPPLSEHNEDVS 1009 NP R+++ Q++ W K YK + + + S Sbjct: 324 NPEKRMSLEQVMRHPWIVK-YKDSWTRKSSESS 355
>Q6P2M8:KCC1B_HUMAN Calcium/calmodulin-dependent protein kinase type 1B - Homo sapiens| (Human) Length = 343 Score = 181 bits (458), Expect = 1e-44 Identities = 106/266 (39%), Positives = 154/266 (57%), Gaps = 7/266 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+ + +G G+F++V +A++ + A+K + + LR K ++ EIA ++ I HPN Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKK-ALRGKEA-LVENEIAVLRRISHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L +V S S +Y+ +E V GGELFD+I+ G E +A Q++ AV Y HS G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 554 YHRDLKPENLLLDS---YGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLL + + VSDFGLS + + +L TACGTP YVAPE+L K Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLS----KIQAGNMLGTACGTPGYVAPELLEQKP 188 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRAN--VSCPPW--FSTGARNLI 892 Y G A DVW+ G+I ++L+ GY PF D + L+ I RA+ P W S A++ I Sbjct: 189 Y-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFI 247 Query: 893 KRILDPNPHTRITIAQILEDEWFKKD 970 + +L+ +P R T Q L W D Sbjct: 248 RHLLERDPQKRFTCQQALRHLWISGD 273
>Q6PGN3:DCLK2_MOUSE Serine/threonine-protein kinase DCLK2 - Mus musculus (Mouse)| Length = 756 Score = 181 bits (458), Expect = 1e-44 Identities = 99/269 (36%), Positives = 155/269 (57%), Gaps = 10/269 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y +GK IG+G+FA VK D G A+K++D+ + + I+ E++ ++ ++HPN Sbjct: 393 YRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHL--IENEVSILRRVKHPN 450 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ L E M + + +++V+E V+GG+LFD I +S K E + + L NA+ Y HS + Sbjct: 451 IIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSI 510 Query: 554 YHRDLKPENLLL----DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 HRD+KPENLL+ D +LK+ DFGL+ T +G L+T CGTP YVAPE++A+ Sbjct: 511 VHRDIKPENLLVCEYPDGTKSLKLGDFGLA-----TVVEGPLYTVCGTPTYVAPEIIAET 565 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLM--TLYK--LISRANVSCPPW--FSTGAR 883 GY G+ DVW+ G+I ++L+ G+ PF N + L+ L + P W + A+ Sbjct: 566 GY-GLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAK 624 Query: 884 NLIKRILDPNPHTRITIAQILEDEWFKKD 970 LI ++L N R T +IL W D Sbjct: 625 ELISQMLQVNVEARCTAGEILSHPWVSDD 653
>O15075:DCLK1_HUMAN Serine/threonine-protein kinase DCLK1 - Homo sapiens (Human)| Length = 740 Score = 181 bits (458), Expect = 1e-44 Identities = 101/282 (35%), Positives = 164/282 (58%), Gaps = 10/282 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++G+TIG+G+FA VK + A+K++ ++ + I+ E++ ++ ++HPN Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKE--HMIQNEVSILRRVKHPN 447 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L E M +++Y+V+E V+GG+LFD I ++ K E +A + L +A+ Y HS + Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNI 507 Query: 554 YHRDLKPENLLL----DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 HRD+KPENLL+ D +LK+ DFGL+ T DG L+T CGTP YVAPE++A+ Sbjct: 508 VHRDIKPENLLVYEHQDGSKSLKLGDFGLA-----TIVDGPLYTVCGTPTYVAPEIIAET 562 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPF----DDPNLMTLYKLISRANVSCPPW--FSTGAR 883 GY G+ D+W+ G+I ++L+ G+ PF DD ++ L+ + + P W S A+ Sbjct: 563 GY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAK 621 Query: 884 NLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVS 1009 LI +L + R + Q+LE W D P +EH V+ Sbjct: 622 ELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPE-NEHQLSVA 662
>Q501V0:KPSH1_DANRE Serine/threonine-protein kinase H1 homolog - Danio rerio| (Zebrafish) (Brachydanio rerio) Length = 422 Score = 180 bits (457), Expect = 2e-44 Identities = 97/262 (37%), Positives = 155/262 (59%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ IG GSF++V + AIK+++ + ++ E E+ ++ +RH N Sbjct: 96 YDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREGREVCES---ELCVLRRVRHTN 152 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++QL EV + ++YMV+E GGELFD+I+ G E +A R +++ V Y H+ G+ Sbjct: 153 IIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGI 212 Query: 554 YHRDLKPENLLLDSYGA---LKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLL GA + ++DFGL A + + D+ L+ T CGTP Y+APE+L K Sbjct: 213 THRDLKPENLLYYHPGADSKIMITDFGL-ASTRKKGDECLMKTTCGTPEYIAPEILVRKP 271 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLI--SRANVSCPPWFSTG--ARNLI 892 Y A D+W+ G+I ++L++G +PF+D N M LY+ I + + S PW S A++ I Sbjct: 272 YTN-AVDMWALGVISYILLSGTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDFI 330 Query: 893 KRILDPNPHTRITIAQILEDEW 958 R+L +P+ R++ Q L+ W Sbjct: 331 DRVLTVDPNERLSAGQALKHPW 352
>P05986:KAPC_YEAST cAMP-dependent protein kinase type 3 - Saccharomyces cerevisiae| (Baker's yeast) Length = 398 Score = 179 bits (455), Expect = 3e-44 Identities = 90/293 (30%), Positives = 165/293 (56%), Gaps = 18/293 (6%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++ +T+G GSF +V + + NG A+K L ++ +++ K VE E + ++ HP Sbjct: 88 FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPF 147 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++++ +++MV++++EGGELF + S + A+ Y ++ A++Y HS+ + Sbjct: 148 IIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDI 207 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPEN+LLD G +K++DFG + + P + +T CGTP+Y+APEV++ K Y+ Sbjct: 208 IYRDLKPENILLDKNGHIKITDFGFAKYVPD-----VTYTLCGTPDYIAPEVVSTKPYN- 261 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 + D WS G++++ ++AGY PF + N M Y+ I A + PP+F A++L+K+++ + Sbjct: 262 KSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRD 321 Query: 914 PHTRITIAQ-----ILEDEWFKK-------------DYKPPLSEHNEDVSLED 1018 R+ Q + WF + Y+PP+ + D S D Sbjct: 322 LSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFD 374
>Q8BWQ5:DCLK3_MOUSE Serine/threonine-protein kinase DCLK3 - Mus musculus (Mouse)| Length = 619 Score = 179 bits (455), Expect = 3e-44 Identities = 95/267 (35%), Positives = 162/267 (60%), Gaps = 10/267 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++G IG+G+FA VK + A+K++D++ + + + + EI ++ + HPN Sbjct: 343 YDIGGVIGDGNFATVKECRHRETKQAYAMKMIDKSQLKGKEDI--VDSEILIIQSLSHPN 400 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LHEV ++++IY+++E+V+GG+LFD IV + K E EA L A+ + H + + Sbjct: 401 IVKLHEVYETEAEIYLIMEYVQGGDLFDAIVENVKFPEPEAAVMITDLCKALVHMHDKNI 460 Query: 554 YHRDLKPENLLL----DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 HRD+KPENLL+ D LK++DFGL+ + + + T CGTP YVAPE+L++K Sbjct: 461 VHRDVKPENLLVQRNEDKSITLKLADFGLAKYVVRP-----IFTVCGTPTYVAPEILSEK 515 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDP--NLMTLYKLI--SRANVSCPPW--FSTGAR 883 GY G+ D+W+ G+IL++L+ G+ PF P + L+ +I + P W S A+ Sbjct: 516 GY-GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAK 574 Query: 884 NLIKRILDPNPHTRITIAQILEDEWFK 964 +L++ +L+ +P R T Q+L+ W + Sbjct: 575 DLVRNLLEVDPKKRYTAEQVLQHPWIE 601
>O64629:AUR3_ARATH Serine/threonine-protein kinase Aurora-3 - Arabidopsis thaliana| (Mouse-ear cress) Length = 288 Score = 179 bits (455), Expect = 3e-44 Identities = 91/264 (34%), Positives = 158/264 (59%), Gaps = 2/264 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F +V +A++ ++ A+KV+ + + ++K+ Q++RE+ +RHPN Sbjct: 22 FEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQLRREMEIQTSLRHPN 81 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L +I+++LE+ GGEL+ + +G L E +A Y L A+ YCH + V Sbjct: 82 ILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCHGKCV 141 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLLD G LK++DFG S S + T CGT +Y+APE++ ++ +D Sbjct: 142 IHRDIKPENLLLDHEGRLKIADFGWSVQSSNKR-----KTMCGTLDYLAPEMVENRDHD- 195 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP--PWFSTGARNLIKRILD 907 A D W+ GI+ + + G PF+ + +K I + ++S P P S A+NLI ++L Sbjct: 196 YAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAKNLISQLLV 255 Query: 908 PNPHTRITIAQILEDEWFKKDYKP 979 +P R++I +I++ W K+ P Sbjct: 256 KDPSKRLSIEKIMQHPWIVKNADP 279
>Q755C4:IPL1_ASHGO Spindle assembly checkpoint kinase - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 367 Score = 179 bits (454), Expect = 4e-44 Identities = 79/259 (30%), Positives = 153/259 (59%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+GK +G+G F +V + +G CA+K +++ ++++ + +Q +RE+ +RHPN Sbjct: 109 FEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLRHPN 168 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 + QL+ + ++Y+++E++ GEL+ + + A Y +Q+ +A+DY H R + Sbjct: 169 LTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALDYMHERNI 228 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPEN+++ +K++DFG S +P+ T CGT +Y++PE++ + Y+ Sbjct: 229 LHRDIKPENIIIGFNNTIKLTDFGWSVITPK---GSKRKTLCGTVDYLSPELIRSREYN- 284 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVW+ G++ + L+ G PF++ + YK I + N+ P T AR+LI R+L+ + Sbjct: 285 EKVDVWALGVLTYELLVGSPPFEEESKELTYKRILKRNLIFPDHVDTEARHLISRLLEYD 344 Query: 914 PHTRITIAQILEDEWFKKD 970 P RI + ++ + W +K+ Sbjct: 345 PGDRIPLKEVKKHPWIEKN 363
>P28178:PK2_DICDI Protein kinase 2 - Dictyostelium discoideum (Slime mold)| Length = 479 Score = 179 bits (453), Expect = 5e-44 Identities = 98/260 (37%), Positives = 147/260 (56%), Gaps = 3/260 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +EL IG+GSF KV K A+KVL ++ ++ K V K E ++ I HP Sbjct: 153 FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPF 212 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V LH +K K+YMVL+FV GGELF + G+ E + Y ++++A+D+ H + + Sbjct: 213 IVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDI 272 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPEN+LLDS G + ++DFGLS T DG T CGTP Y+APEVL G+ G Sbjct: 273 VYRDLKPENILLDSEGHICITDFGLSKKIETT--DGTF-TFCGTPEYLAPEVLNGHGH-G 328 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D WS G +L+ ++ G PF N+ T+Y+ I + P + S A++L++ +L Sbjct: 329 CAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLLEGLLTRE 388 Query: 914 PHTRITI---AQILEDEWFK 964 R+ ++ + WFK Sbjct: 389 VDKRLGTKGGGEVKQHPWFK 408
>Q4KTY1:KPSH1_PINFU Serine/threonine-protein kinase H1 homolog - Pinctada fucata (Pearl| oyster) Length = 415 Score = 179 bits (453), Expect = 5e-44 Identities = 110/318 (34%), Positives = 168/318 (52%), Gaps = 7/318 (2%) Frame = +2 Query: 26 QNNGRQEERDRDHTSDPPDLIHR*FIGPPPPPWRKLXXXXXXXXXXXXXXXXXXXXYELG 205 + N Q RD T DP + GPPP R Y++ Sbjct: 33 RQNPHQNRGPRDPTKDPKNA------GPPPEGQRS---NRKVKKYRDKFDPRVTAKYDIK 83 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 IG G+F+KV + AIK++DR ++ K E + E+A ++ ++H ++QL Sbjct: 84 ALIGRGNFSKVVRVEHRVTKQPYAIKMIDR---VQGK--EVFESEVAVLRRVKHSYIIQL 138 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 EV +K K+YMV+E GGELFD+I+ G E +A R + +++ V Y H G+ HRD Sbjct: 139 IEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNMVLDGVKYLHGLGITHRD 198 Query: 566 LKPENLLLDSYG---ALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGM 736 LKPENLL G + ++DFGLS S + + + T CGTP Y+APE++A K Y Sbjct: 199 LKPENLLYYHPGHDSKIMITDFGLS--STRKGPENFMRTTCGTPEYIAPEIIARKPY-MC 255 Query: 737 AADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSC--PPW--FSTGARNLIKRIL 904 D+W+ G+I ++L++G +PFDD N LY+LI +A S W S A++ I ++L Sbjct: 256 QVDMWAVGVITYILLSGTMPFDDENKTRLYRLILKAKYSYAGEHWKDVSAQAKDFIDKLL 315 Query: 905 DPNPHTRITIAQILEDEW 958 +P R++ A L+ +W Sbjct: 316 VVSPGDRLSAADALKHQW 333
>Q9HFF4:PPK1_SCHPO Serine/threonine-protein kinase ppk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1023 Score = 178 bits (452), Expect = 6e-44 Identities = 106/284 (37%), Positives = 163/284 (57%), Gaps = 27/284 (9%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKV------AKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMK 355 Y LG+TIG G F KVK+ A T + +T + + ++ ++ RE+A +K Sbjct: 492 YILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNCQTSRLMREVAILK 551 Query: 356 LI--RHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAV 529 + HP++V+ + + +K +VL++V GGELFD I+ +L + A R F QLI+ V Sbjct: 552 GLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLISGV 611 Query: 530 DYCHSRGVYHRDLKPENLLLDSYGALKVSDFG----------LSAFSPQTKDDGLLHTAC 679 Y HSRGV HRDLK EN+LLD+ + ++DFG LS S T+ L T+C Sbjct: 612 AYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTFGHFNTLSEHSLPTEKPDLFSTSC 671 Query: 680 GTPNYVAPEVLADKG--YDGMAADVWSCGIILFVLMAGYLPFDD-------PNLMTLYKL 832 G+P Y APE++ K Y G AD+WSCG+IL+ ++AGYLPFDD N+ LY+ Sbjct: 672 GSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPFDDDPHNPNGENVPRLYRY 731 Query: 833 ISRANVSCPPWFSTGARNLIKRILDPNPHTRITIAQILEDEWFK 964 I + P +F + AR+++K+IL P+P R+ ++ I+ + + Sbjct: 732 ICSTPLIFPEFFKSKARDILKKILVPDPAKRVRMSAIMNHAYLR 775
>P34099:KAPC_DICDI cAMP-dependent protein kinase catalytic subunit - Dictyostelium| discoideum (Slime mold) Length = 648 Score = 178 bits (451), Expect = 8e-44 Identities = 95/304 (31%), Positives = 169/304 (55%) Frame = +2 Query: 17 IPKQNNGRQEERDRDHTSDPPDLIHR*FIGPPPPPWRKLXXXXXXXXXXXXXXXXXXXXY 196 I +Q +Q+ + + PP ++ F+ PP +L + Sbjct: 295 IRQQQQSQQQLQQQQLQQIPPPTVNSFFLPPPVNARERLKE------------------F 336 Query: 197 ELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNV 376 + + +G G+F KV + ++T++G A+K L++ +V++ K VE + E + + I HP + Sbjct: 337 KQIRVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFI 396 Query: 377 VQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVY 556 V L++ + K+Y++ E+V GGE+F + S K A+ Y +++ A+++ H + + Sbjct: 397 VNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQNIV 456 Query: 557 HRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGM 736 +RDLKPENLL+D+ G +K++DFG F+ + +D T CGTP Y+APE++ KG+ G Sbjct: 457 YRDLKPENLLIDNQGHIKITDFG---FAKRVED--RTFTLCGTPEYLAPEIIQSKGH-GK 510 Query: 737 AADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPNP 916 A D W+ GI++F ++AGY PF D + +Y I ++ P F A++LIKR+L + Sbjct: 511 AVDWWALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRLLTADR 570 Query: 917 HTRI 928 R+ Sbjct: 571 TRRL 574
>Q09170:CDS1_SCHPO Serine/threonine-protein kinase cds1 - Schizosaccharomyces pombe| (Fission yeast) Length = 460 Score = 178 bits (451), Expect = 8e-44 Identities = 102/292 (34%), Positives = 162/292 (55%), Gaps = 14/292 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVL----RHKMVEQIKREIATMKLI 361 YE+ +T+G G+FA VK+A + +G AIK++++ +L + E +REI +K + Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSL 226 Query: 362 RHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCH 541 HP VVQ HE+ + ++++V+E+VEGG+L D ++ +G + E + + QL+ + + H Sbjct: 227 HHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLH 286 Query: 542 SRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 +GV HRD+KPEN+L+ + LK+SDFGL+ T L T CGT Y+APEVL K Sbjct: 287 KQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGT--GTFLETFCGTMGYLAPEVLKSK 344 Query: 722 ------GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPW----FS 871 GYD D+WS G +L+V++ +PF + +LIS+ P S Sbjct: 345 NVNLDGGYDD-KVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEIS 403 Query: 872 TGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDA 1027 +LI R+L+ NP RI+ ++ L+ WF Y EH S + +A Sbjct: 404 EEGIDLINRMLEINPEKRISESEALQHPWF---YTVSTHEHRTPPSSSEHEA 452
>O01427:AIR2_CAEEL Aurora/Ipl1-related protein kinase 2 - Caenorhabditis elegans| Length = 305 Score = 178 bits (451), Expect = 8e-44 Identities = 88/257 (34%), Positives = 145/257 (56%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A+ AIKVL ++ ++ + Q++REI + HPN Sbjct: 30 FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPN 89 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ KIY+VLE+ GGE++ ++ S + E A +Y +++ +A+ YCH + V Sbjct: 90 IIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYMYEIADALSYCHRKNV 149 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLL+ S G LK+ DFG S +P K T CGT +Y+ PE++ + Sbjct: 150 IHRDIKPENLLIGSQGELKIGDFGWSVHAPSNK----RQTMCGTMDYLPPEMVNGADHSD 205 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D+W+ G++ + + G PF+ + Y I A + P GAR+LI R+L + Sbjct: 206 -AVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDLIGRLLVVD 264 Query: 914 PHTRITIAQILEDEWFK 964 P R T+ Q+ E W + Sbjct: 265 PKARCTLEQVKEHYWIQ 281
>Q96PN8:TSSK3_HUMAN Testis-specific serine/threonine-protein kinase 3 - Homo sapiens| (Human) Length = 268 Score = 177 bits (450), Expect = 1e-43 Identities = 98/258 (37%), Positives = 155/258 (60%), Gaps = 3/258 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+LGKTIGEG+++KVK A ++ AIKV+D+ + + RE+ ++ + H N Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 374 VVQLHEVMASKS-KIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 ++Q++E++ S KI +V+E EGG++FD ++N G L E A+ F Q++ A+ YCH G Sbjct: 70 IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129 Query: 551 VYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYD 730 V HRDLK EN LL + LK++DFG + P++ + L T CG+ Y APEVL +D Sbjct: 130 VAHRDLKCENALLQGFN-LKLTDFGFAKVLPKSHRE-LSQTFCGSTAYAAPEVLQGIPHD 187 Query: 731 GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGA--RNLIKRIL 904 DVWS G++L+V++ LPFDD ++ + + VS P S A ++L+KR+L Sbjct: 188 SKKGDVWSMGVVLYVMLCASLPFDDTDIPKML-WQQQKGVSFPTHLSISADCQDLLKRLL 246 Query: 905 DPNPHTRITIAQILEDEW 958 +P+ R +I ++ W Sbjct: 247 EPDMILRPSIEEVSWHPW 264
>Q6C3J2:IPL1_YARLI Spindle assembly checkpoint kinase - Yarrowia lipolytica (Candida| lipolytica) Length = 371 Score = 177 bits (450), Expect = 1e-43 Identities = 90/275 (32%), Positives = 153/275 (55%), Gaps = 6/275 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+GK +G+G F KV + KD + G A+K +++ ++ + +Q +RE+ +RH N Sbjct: 99 FEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQSNLRHTN 158 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 V++L K ++Y++LE+V GEL+ + N + E A Y +Q+ A+ Y H + + Sbjct: 159 VLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHGKNI 218 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPEN+LL +K+SDFG S +P + T CGT +Y+ PE++ + YD Sbjct: 219 IHRDIKPENILLHFNDTIKISDFGWSVHAPSNRRS----TLCGTMDYLPPEIVQSRPYD- 273 Query: 734 MAADVWSCGIILFVLMAGYLPFDDP-NLMTLYKLISRANVSCPPWFSTGARNLIKRILDP 910 DVWS GI+++ + G PF++P Y+ I + ++ PP+ S A +LIKR+L Sbjct: 274 KNVDVWSLGILMYEFLCGAPPFEEPGGAQATYRRIVKLDLRIPPYVSADAADLIKRMLTL 333 Query: 911 NPHTRITIAQILEDEWFKK-----DYKPPLSEHNE 1000 +P R + + + W + YK P + +E Sbjct: 334 DPAKRFKLKDMHKHPWIVRLRPTWKYKVPKTASHE 368
>Q91YA2:KPSH1_MOUSE Serine/threonine-protein kinase H1 - Mus musculus (Mouse)| Length = 424 Score = 176 bits (447), Expect = 2e-43 Identities = 98/262 (37%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ IG GSF++V + AIK+++ + ++ E E+ ++ +RH N Sbjct: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCES---ELRVLRRVRHAN 154 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++QL EV ++ ++YMV+E GGELFD+I+ G E +A R +++ V Y H+ G+ Sbjct: 155 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 214 Query: 554 YHRDLKPENLLLDSYGA---LKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLL G + ++DFGL A + + DD L+ T CGTP Y+APEVL K Sbjct: 215 THRDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVRKP 273 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSC--PPWFSTG--ARNLI 892 Y + D+W+ G+I ++L++G +PF+D N LY+ I R S PW S A++ I Sbjct: 274 YTN-SVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFI 332 Query: 893 KRILDPNPHTRITIAQILEDEW 958 R+L +P R+T Q L W Sbjct: 333 DRLLTVDPGARMTALQALRHPW 354
>P11801:KPSH1_HUMAN Serine/threonine-protein kinase H1 - Homo sapiens (Human)| Length = 424 Score = 176 bits (447), Expect = 2e-43 Identities = 98/262 (37%), Positives = 152/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ IG GSF++V + AIK+++ + ++ E E+ ++ +RH N Sbjct: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCES---ELRVLRRVRHAN 154 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++QL EV ++ ++YMV+E GGELFD+I+ G E +A R +++ V Y H+ G+ Sbjct: 155 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 214 Query: 554 YHRDLKPENLLLDSYGA---LKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLL G + ++DFGL A + + DD L+ T CGTP Y+APEVL K Sbjct: 215 THRDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVRKP 273 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPWFSTG--ARNLI 892 Y + D+W+ G+I ++L++G +PF+D N LY+ I R + S PW S A++ I Sbjct: 274 YTN-SVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFI 332 Query: 893 KRILDPNPHTRITIAQILEDEW 958 R+L +P R+T Q L W Sbjct: 333 DRLLTVDPGARMTALQALRHPW 354
>Q0V7M1:KPSH1_BOVIN Serine/threonine-protein kinase H1 - Bos taurus (Bovine)| Length = 424 Score = 176 bits (447), Expect = 2e-43 Identities = 98/262 (37%), Positives = 152/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ IG GSF++V + AIK+++ + ++ E E+ ++ +RH N Sbjct: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCES---ELRVLRRVRHAN 154 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++QL EV ++ ++YMV+E GGELFD+I+ G E +A R +++ V Y H+ G+ Sbjct: 155 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 214 Query: 554 YHRDLKPENLLLDSYGA---LKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLL G + ++DFGL A + + DD L+ T CGTP Y+APEVL K Sbjct: 215 THRDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVRKP 273 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPWFSTG--ARNLI 892 Y + D+W+ G+I ++L++G +PF+D N LY+ I R + S PW S A++ I Sbjct: 274 YTN-SVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFI 332 Query: 893 KRILDPNPHTRITIAQILEDEW 958 R+L +P R+T Q L W Sbjct: 333 DRLLTVDPGARMTALQALRHPW 354
>Q6CWQ4:IPL1_KLULA Spindle assembly checkpoint kinase - Kluyveromyces lactis (Yeast)| (Candida sphaerica) Length = 361 Score = 176 bits (447), Expect = 2e-43 Identities = 83/255 (32%), Positives = 150/255 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+GK +G+G F KV K G CA+K +++ ++++ + +Q +RE+ +H N Sbjct: 100 FEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFKHKN 159 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 + QL+ + ++Y+++E+V GEL+ + N+G L E A + +Q+ NA+DY HS+ + Sbjct: 160 LTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKNI 219 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPEN+L+ +K++DFG S ++ +D T CGT +Y++PE++ + Y+ Sbjct: 220 LHRDIKPENILIGFNNTIKLTDFGWSVYN---EDGQKRKTLCGTIDYLSPELIKSREYNN 276 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVW+ G++ + L+ G PF++ Y+ I R ++ P S AR+LI R+L Sbjct: 277 -KVDVWALGVLTYELLVGSPPFEEDTKEMTYRRILRCDLKFPLNVSPQARDLIVRLLQFE 335 Query: 914 PHTRITIAQILEDEW 958 P RI ++++ W Sbjct: 336 PSKRIPLSEVKSHAW 350
>Q61XD3:AIR2_CAEBR Aurora/Ipl1-related protein kinase 2 - Caenorhabditis briggsae| Length = 302 Score = 176 bits (447), Expect = 2e-43 Identities = 82/255 (32%), Positives = 145/255 (56%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A+ CAIKVL ++ ++ + Q++REI ++HPN Sbjct: 27 FEIGRPLGKGKFGSVYLARTKTGHFHCAIKVLFKSQLISGGVEHQLEREIEIQSHLQHPN 86 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ KIY++LE+ GGE++ ++ + E A +Y +++ +A+ YCH + V Sbjct: 87 IIRLYNYFWDAKKIYLILEYAPGGEMYKQLTTQKRFTEAMAGKYMYEIADALSYCHRKNV 146 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLL+ + G LK+ DFG S +P K T CGT +Y+ PE++ + Sbjct: 147 IHRDIKPENLLIGAQGELKIGDFGWSVHAPSNK----RQTMCGTMDYLPPEMVNGNSHSD 202 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D+W+ G++ + + G PF+ N Y I + P + GAR+LI ++L + Sbjct: 203 -AVDLWAIGVLCYEFLVGKPPFEHENQADTYSAIKAGRFTYPDFVKKGARDLIGKLLVVD 261 Query: 914 PHTRITIAQILEDEW 958 P R ++ ++ + W Sbjct: 262 PRRRCSLQEVKDHYW 276
>O61267:LOK_DROME Ovarian-specific serine/threonine-protein kinase Lok - Drosophila| melanogaster (Fruit fly) Length = 476 Score = 176 bits (446), Expect = 3e-43 Identities = 98/272 (36%), Positives = 155/272 (56%), Gaps = 15/272 (5%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHV------LRHKMVEQIKREIATMK 355 Y + + +G G++ V++ DTR A+K++ +N + +++ E MK Sbjct: 174 YYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMK 233 Query: 356 LIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDY 535 + HP VV++H+++ +YMVLEF+ GG+L ++I+++ L ED ++ YF+Q+ +AV Y Sbjct: 234 NLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKY 293 Query: 536 CHSRGVYHRDLKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPE 706 H RG+ HRDLKP+N+LL D LKVSDFGLS F + D ++ T CGTP YVAPE Sbjct: 294 LHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKF---VQKDSVMRTLCGTPLYVAPE 350 Query: 707 VLADKGYDGMA--ADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSC--PPWFST 874 VL G + D+WS G++LF ++G LPF D + I + + P W S Sbjct: 351 VLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSV 410 Query: 875 G--ARNLIKRILDPNPHTRITIAQILEDEWFK 964 A+ LI ++L +P R +I +L+ W + Sbjct: 411 SQRAKLLINQMLIVDPERRPSIDDVLQSSWLR 442
>O55099:AURKB_RAT Serine/threonine-protein kinase 12 - Rattus norvegicus (Rat)| Length = 343 Score = 176 bits (446), Expect = 3e-43 Identities = 83/257 (32%), Positives = 149/257 (57%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A++ ++ A+K+L ++ + + + Q++REI ++HPN Sbjct: 80 FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPN 139 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++QL+ + +IY++LE+ GEL+ ++ SG E +L +A+ YCH + V Sbjct: 140 ILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELSDALMYCHKKKV 199 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL G LK++DFG S +P + T CGT +Y+ PE++ + ++ Sbjct: 200 IHRDIKPENLLLGLQGELKIADFGWSVHAPSLR----RKTMCGTLDYLPPEMIEGRMHNE 255 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 M D+W G++ + LM G PF+ P+ Y+ I + ++ P GA++LI ++L N Sbjct: 256 M-VDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMPLGAKDLISKLLKHN 314 Query: 914 PHTRITIAQILEDEWFK 964 P R+ + Q+ W + Sbjct: 315 PSQRLPLEQVSAHPWVR 331
>P06245:KAPB_YEAST cAMP-dependent protein kinase type 2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 380 Score = 176 bits (445), Expect = 4e-43 Identities = 99/293 (33%), Positives = 160/293 (54%), Gaps = 18/293 (6%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++ +T+G GSF +V + + NG AIKVL + V++ K VE E +KL+ HP Sbjct: 70 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPF 129 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++++ I+MV++++EGGELF + S + A+ Y ++I A++Y H+ + Sbjct: 130 LIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNI 189 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPEN+LLD G +K++DFG A QT + T CGTP+Y+APEV+ K Y+ Sbjct: 190 IYRDLKPENILLDRNGHIKITDFGF-AKEVQT----VTWTLCGTPDYIAPEVITTKPYN- 243 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 + D WS G++++ ++AGY PF D M Y+ I + V PP+F +L+ +++ + Sbjct: 244 KSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITAD 303 Query: 914 PHTRITIAQ-----ILEDEWFKK-------------DYKPPLSEHNEDVSLED 1018 RI Q I WF + Y+PP++ D SL D Sbjct: 304 LTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFD 356
>O61661:CHK1_DROME Serine/threonine-protein kinase grp - Drosophila melanogaster (Fruit| fly) Length = 512 Score = 176 bits (445), Expect = 4e-43 Identities = 104/336 (30%), Positives = 182/336 (54%), Gaps = 6/336 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHK-MVEQIKREIATMKLIRHP 370 + L +T+GEG++ +VK+ + + G A+K++D + +H +++E+ K+++ Sbjct: 22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVD---LKKHPDAANSVRKEVCIQKMLQDK 78 Query: 371 NVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 ++++ + S Y+ LE+ GGELFD+I + + EA+RYF QL++ ++Y H RG Sbjct: 79 HILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRG 138 Query: 551 VYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYD 730 + HRDLKPENLLLD + +K+SDFG++ + LL CGT YVAPEVL K Y Sbjct: 139 IAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYH 197 Query: 731 GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSC---PPW--FSTGARNLIK 895 AD+WSCG+IL ++AG LP+D P+ R N PW T A +L++ Sbjct: 198 AQPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLR 257 Query: 896 RILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREK 1075 ++L +P TR+T+ + L+ +W + +++ L D AA + + + K Sbjct: 258 KLLATSPGTRLTLEKTLDHKWCNMQF----ADNERSYDLVDSAAALE------ICSPKAK 307 Query: 1076 PESMNAFALISRSAGFNLGNLFEKEMMGMVKRETSF 1183 + + + A +S ++ + + M ++ + F Sbjct: 308 RQRLQSSAHLSNGLDDSISRNYCSQPMPTMRSDDDF 343
>Q9UQB9:AURKC_HUMAN Serine/threonine-protein kinase 13 - Homo sapiens (Human)| Length = 309 Score = 175 bits (444), Expect = 5e-43 Identities = 87/255 (34%), Positives = 147/255 (57%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A+ + A+KVL ++ + + + Q++REI ++HPN Sbjct: 43 FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPN 102 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ ++Y++LE+ GEL+ ++ S KL E +L +A+ YCH + V Sbjct: 103 ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKV 162 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL G +K++DFG S +P + T CGT +Y+ PE++ + YD Sbjct: 163 IHRDIKPENLLLGFRGEVKIADFGWSVHTPSLR----RKTMCGTLDYLPPEMIEGRTYD- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+W G++ + L+ GY PF+ + Y+ I + +V P GAR+LI R+L Sbjct: 218 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 277 Query: 914 PHTRITIAQILEDEW 958 P R+ +AQIL+ W Sbjct: 278 PLERLPLAQILKHPW 292
>O88445:AURKC_MOUSE Serine/threonine-protein kinase 13 - Mus musculus (Mouse)| Length = 282 Score = 175 bits (443), Expect = 7e-43 Identities = 84/258 (32%), Positives = 150/258 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G G F +V +A+ N A+KVL ++ + + + Q++RE+ ++H N Sbjct: 16 FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRN 75 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ ++IY++LE+ GGEL+ ++ KL + +L +A+ YCH + V Sbjct: 76 ILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKV 135 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL G +K+SDFG S +P + T CGT +Y+ PE++A K Y+ Sbjct: 136 IHRDIKPENLLLGLNGEVKISDFGWSVHTPSLR----RKTMCGTLDYLPPEMIAQKPYNE 191 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 M D+W G++ + L+ G PF+ Y+ I + + P GA++LI ++L + Sbjct: 192 M-VDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYH 250 Query: 914 PHTRITIAQILEDEWFKK 967 P R+++AQ+L+ W ++ Sbjct: 251 PSERLSLAQVLKHPWVRE 268
>O70126:AURKB_MOUSE Serine/threonine-protein kinase 12 - Mus musculus (Mouse)| Length = 345 Score = 174 bits (442), Expect = 9e-43 Identities = 82/257 (31%), Positives = 150/257 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A++ ++ A+K+L ++ + + + Q++REI ++HPN Sbjct: 82 FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPN 141 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++QL+ + +IY++LE+ GEL+ ++ S E +L +A+ YCH + V Sbjct: 142 ILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDALTYCHKKKV 201 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL G LK++DFG S +P + T CGT +Y+ PE++ + ++ Sbjct: 202 IHRDIKPENLLLGLQGELKIADFGWSVHAPSLR----RKTMCGTLDYLPPEMIEGRMHNE 257 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 M D+W G++ + LM G PF+ P+ Y+ I + ++ P +GA++LI ++L N Sbjct: 258 M-VDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDLISKLLKHN 316 Query: 914 PHTRITIAQILEDEWFK 964 P R+ +A++ W + Sbjct: 317 PWQRLPLAEVAAHPWVR 333
>P13185:KIN1_YEAST Protein kinase KIN1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1064 Score = 174 bits (440), Expect = 2e-42 Identities = 94/289 (32%), Positives = 153/289 (52%), Gaps = 26/289 (8%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDR------------------NHVLRH-- 313 +E +T+G GS KVK+AK CA+K+++R VL Sbjct: 120 WEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQK 179 Query: 314 KMVEQIKREIATMK------LIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSG 475 K+ ++I R+ T++ ++ HP++ +L E+ + YM+ E+V GG+L D I+ G Sbjct: 180 KLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHG 239 Query: 476 KLGEDEARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKD 655 + E +AR++ + +A+ Y H+ + HRDLK EN+++ +K+ DFGLS K Sbjct: 240 SIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRKQ 299 Query: 656 DGLLHTACGTPNYVAPEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLI 835 LHT CG+ + APE+L Y G DVWS G++LFVL+ G +PFDD N L++ I Sbjct: 300 ---LHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKI 356 Query: 836 SRANVSCPPWFSTGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPP 982 + V P S +L+ ++L +P R T+ Q++E W + + P Sbjct: 357 KQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVRGFNGP 405
>Q6NW76:AURKB_DANRE Serine/threonine-protein kinase 12 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 320 Score = 173 bits (439), Expect = 2e-42 Identities = 80/267 (29%), Positives = 154/267 (57%), Gaps = 3/267 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++G+ +G+G F V +A++ + A+KVL ++ +++ + Q++REI +RHPN Sbjct: 53 FDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLRHPN 112 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++ + ++++++LE+ GE++ ++ G+ + Y ++ +A+ YCH + V Sbjct: 113 ILRFYNYFHDDTRVFLILEYAPRGEMYKELQRYGRFDDQRTATYMEEVSDALQYCHEKKV 172 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL G LK++DFG S +P + T CGT +Y+ PE++ +D Sbjct: 173 IHRDIKPENLLLGYRGELKIADFGWSVHAPSLR----RRTMCGTLDYLPPEMIEGHSHD- 227 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS G++ + + G PF+ + YK I++ ++ P S GAR+LI ++L + Sbjct: 228 EKVDLWSIGVLCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHS 287 Query: 914 PHTRITIAQILEDEWFKKDYK---PPL 985 P R+ + ++E W K + + PP+ Sbjct: 288 PSMRLPLRSVMEHPWVKANSRRVLPPV 314
>P25323:MYLK_DICDI Myosin light chain kinase - Dictyostelium discoideum (Slime mold)| Length = 295 Score = 172 bits (437), Expect = 3e-42 Identities = 96/266 (36%), Positives = 152/266 (57%), Gaps = 7/266 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE + +G G+F+ V + ++ + AIKV++++ L + +K E+ +K + HPN Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSE-LGKDYEKNLKMEVDILKKVNHPN 66 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ L E+ + K+Y+V+E V GGELFDKIV G E +A ++++AV Y H + Sbjct: 67 IIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNI 126 Query: 554 YHRDLKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL +++ + ++DFGLS QT ++ TACGTP+YVAPEVL G Sbjct: 127 VHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTL---VMQTACGTPSYVAPEVLNATG 183 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPP--W--FSTGARNLI 892 YD D+WS G+I ++L+ G+ PF + +++ I AN P W S A++ I Sbjct: 184 YD-KEVDMWSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFI 242 Query: 893 KRILDPNPHTRITIAQILEDEWFKKD 970 ++L + R+ L W K + Sbjct: 243 GKLLVVDVSKRLNATNALNHPWLKSN 268
>P13186:KIN2_YEAST Serine/threonine-protein kinase KIN2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 1147 Score = 172 bits (437), Expect = 3e-42 Identities = 97/291 (33%), Positives = 154/291 (52%), Gaps = 28/291 (9%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDR--------NHVL-----------RHK 316 +E +T+G GS KVK+ K + C IK+++R H L R K Sbjct: 99 WEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQK 158 Query: 317 MVEQ-------IKREIATMKLIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSG 475 +E+ RE + +++ HP++ +L E+ + YM+ E+V GG+L D I+ G Sbjct: 159 RLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHG 218 Query: 476 KLGEDEARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKD 655 L E AR++ + +A+ Y H+ + HRDLK EN+++ S G +K+ DFGLS K Sbjct: 219 SLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQ 278 Query: 656 DGLLHTACGTPNYVAPEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLI 835 LHT CG+ + APE+L + Y G D+WS GI+L+VL+ G +PFDD N L++ I Sbjct: 279 ---LHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKI 335 Query: 836 SRANVSCPPWFSTGARNLIKRILDPNPHTRITIAQILEDEWFKK--DYKPP 982 + V P S +L+ R++ +P R T+ ++E W + D+K P Sbjct: 336 KKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYDFKAP 386
>P21137:KAPC_CAEEL cAMP-dependent protein kinase catalytic subunit - Caenorhabditis| elegans Length = 404 Score = 172 bits (437), Expect = 3e-42 Identities = 96/257 (37%), Positives = 146/257 (56%), Gaps = 5/257 (1%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 KT+G GSF +V + K ++G A+K+LD+ V++ K VE E ++ I P +V + Sbjct: 85 KTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNM 144 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 S +YMVLEF+ GGE+F + G+ E +R Y Q++ A +Y HS + +RD Sbjct: 145 TFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRD 204 Query: 566 LKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAAD 745 LKPENLL+DS G LK++DFG F+ + K G T CGTP Y+APE++ KGY+ A D Sbjct: 205 LKPENLLIDSTGYLKITDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVD 258 Query: 746 VWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPNPHTR 925 W+ G++++ + AGY PF + +Y+ I V P FS ++L+K +L + R Sbjct: 259 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKR 318 Query: 926 I-----TIAQILEDEWF 961 +A I +WF Sbjct: 319 YGNLKNGVADIKNHKWF 335
>Q61241:TSSK1_MOUSE Testis-specific serine/threonine-protein kinase 1 - Mus musculus| (Mouse) Length = 364 Score = 172 bits (436), Expect = 4e-42 Identities = 100/261 (38%), Positives = 148/261 (56%), Gaps = 6/261 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y +G +GEGS+AKVK A R A+K++DR + + + REI + ++ H + Sbjct: 12 YIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPSDFLEKFLPREIEILAMLNHRS 71 Query: 374 VVQLHEVMA-SKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 +V+ +E+ A S K+Y+V+E G+L + I G L ED+AR+ FHQL +A+ YCH Sbjct: 72 IVKTYEIFATSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDLD 131 Query: 551 VYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDG----LLHTACGTPNYVAPEVLAD 718 V HRDLK ENLLLD +K+SDFG S +DD L T CG+ Y APEVL Sbjct: 132 VVHRDLKSENLLLDKDFNIKLSDFGFS--KRCLRDDSGRLILSKTFCGSAAYAAPEVLQG 189 Query: 719 KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTL-YKLISRANVSCPPWFSTGARNLIK 895 Y D+WS G+IL++++ G +P+DD N+ L + R N + ++LI Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKLRIQKEHRVNFPRSKHLTGECKDLIY 249 Query: 896 RILDPNPHTRITIAQILEDEW 958 R+L P+ + R+ I +IL W Sbjct: 250 RMLQPDVNRRLHIDEILNHCW 270
>Q96NX5:KCC1G_HUMAN Calcium/calmodulin-dependent protein kinase type 1G - Homo sapiens| (Human) Length = 476 Score = 172 bits (436), Expect = 4e-42 Identities = 95/258 (36%), Positives = 145/258 (56%), Gaps = 7/258 (2%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 + +G G+F++V + K G A+K + ++ R +E EIA +K I+H N+V L Sbjct: 27 EVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLEN---EIAVLKKIKHENIVTL 83 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 ++ S + Y+V++ V GGELFD+I+ G E +A Q+++AV Y H G+ HRD Sbjct: 84 EDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRD 143 Query: 566 LKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGM 736 LKPENLL + + ++DFGLS + + +G++ TACGTP YVAPEVLA K Y Sbjct: 144 LKPENLLYLTPEENSKIMITDFGLS----KMEQNGIMSTACGTPGYVAPEVLAQKPY-SK 198 Query: 737 AADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLIKRIL 904 A D WS G+I ++L+ GY PF + L++ I P W S A++ I +L Sbjct: 199 AVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLL 258 Query: 905 DPNPHTRITIAQILEDEW 958 + +P+ R T + L W Sbjct: 259 EKDPNERYTCEKALSHPW 276
>Q9Z265:CHK2_MOUSE Serine/threonine-protein kinase Chk2 - Mus musculus (Mouse)| Length = 546 Score = 172 bits (436), Expect = 4e-42 Identities = 107/317 (33%), Positives = 167/317 (52%), Gaps = 20/317 (6%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVE-----QIKREIATMKL 358 Y + KT+G G+ +VK+A + + AIK++ + E ++ EI +K Sbjct: 224 YIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEILKK 283 Query: 359 IRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYC 538 + HP ++++ +V ++ Y+VLE +EGGELFD++V + +L E + YF+Q++ AV Y Sbjct: 284 LNHPCIIKIKDVFDAED-YYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYL 342 Query: 539 HSRGVYHRDLKPENLLLDSYG---ALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEV 709 H G+ HRDLKPEN+LL S +K++DFG S +T L+ T CGTP Y+APEV Sbjct: 343 HENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGET---SLMRTLCGTPTYLAPEV 399 Query: 710 LADKGYDG--MAADVWSCGIILFVLMAGYLPFDDPNLMTLYK---LISRANVSCPPW--F 868 L G G A D WS G+ILF+ ++GY PF + K + N W Sbjct: 400 LVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWTDV 459 Query: 869 STGARNLIKRILDPNPHTRITIAQI-----LEDEWFKKDYKPPLSEHNEDVSLEDVDAAF 1033 S A +L+K++L +P R+T + L+DE+ KK ++ L + V+L A Sbjct: 460 SEEALDLVKKLLVVDPKARLTTEEALNHPWLQDEYMKKKFQDLLVQEKNSVTLPVAPAQT 519 Query: 1034 DSSEEHLVAERREKPES 1084 S + L E P + Sbjct: 520 SSQKRPLELEVEGMPST 536
>Q9BXA7:TSSK1_HUMAN Testis-specific serine/threonine-protein kinase 1 - Homo sapiens| (Human) Length = 367 Score = 172 bits (435), Expect = 6e-42 Identities = 98/264 (37%), Positives = 148/264 (56%), Gaps = 7/264 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LG +GEGS+AKVK A R AIK++DR + + + REI + ++ H + Sbjct: 12 YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCS 71 Query: 374 VVQLHEVM-ASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 +++ +E+ S K+Y+V+E G+L + I G L EDEAR+ FHQL A+ YCH Sbjct: 72 IIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131 Query: 551 VYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDD----GLLHTACGTPNYVAPEVLAD 718 V HRDLK +NLLLD +K+SDF S +DD L T CG+P Y APEVL Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFS--KRCLRDDSGRMALSKTFCGSPAYAAPEVLQG 189 Query: 719 KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP--PWFSTGARNLI 892 Y D+WS G+IL++++ G +P+DD N+ + ++ V+ P + ++LI Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLI 249 Query: 893 KRILDPNPHTRITIAQILEDEWFK 964 +L P+ + R+ I +IL W + Sbjct: 250 YHMLQPDVNRRLHIDEILSHCWMQ 273
>P54644:KRAC_DICDI RAC-family serine/threonine-protein kinase homolog - Dictyostelium| discoideum (Slime mold) Length = 444 Score = 171 bits (434), Expect = 7e-42 Identities = 95/273 (34%), Positives = 152/273 (55%), Gaps = 10/273 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +EL +G+GSF KV + G A+KVL + H++ H VE E ++ I HP Sbjct: 120 FELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKINHPF 179 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L+ ++ K+Y +L++V GGELF + K ED R Y +++ A+++ H GV Sbjct: 180 LVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGV 239 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLLL + G + ++DFGL T D T CGTP Y+APEVL GY G Sbjct: 240 IYRDLKPENLLLTNEGHICMTDFGLCKEGLLTPTD-KTGTFCGTPEYLAPEVLQGNGY-G 297 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D WS G +L+ ++ G PF + ++ +Y+ I +S P + S AR+L++++L+ + Sbjct: 298 KQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLEQLLERD 357 Query: 914 PHTRITIAQILE----------DEWFKKDYKPP 982 P R+ +++ ++ F+K+ PP Sbjct: 358 PEKRLADPNLIKRHPFFRSIDWEQLFQKNIPPP 390
>Q7TNJ7:KCC1G_RAT Calcium/calmodulin-dependent protein kinase type 1G - Rattus| norvegicus (Rat) Length = 476 Score = 171 bits (434), Expect = 7e-42 Identities = 95/258 (36%), Positives = 145/258 (56%), Gaps = 7/258 (2%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 + +G G+F++V + K G A+K + ++ R +E EIA +K I+H N+V L Sbjct: 27 EVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLEN---EIAVLKRIKHENIVTL 83 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 ++ S + Y+V++ V GGELFD+I+ G E +A Q+++AV Y H G+ HRD Sbjct: 84 EDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRD 143 Query: 566 LKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGM 736 LKPENLL + + ++DFGLS + + +G++ TACGTP YVAPEVLA K Y Sbjct: 144 LKPENLLYLTPEENSKIMITDFGLS----KMEQNGVMSTACGTPGYVAPEVLAQKPY-SK 198 Query: 737 AADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLIKRIL 904 A D WS G+I ++L+ GY PF + L++ I P W S A++ I +L Sbjct: 199 AVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLL 258 Query: 905 DPNPHTRITIAQILEDEW 958 + +P+ R T + L W Sbjct: 259 EKDPNERYTCEKALRHPW 276
>Q91VB2:KCC1G_MOUSE Calcium/calmodulin-dependent protein kinase type 1G - Mus musculus| (Mouse) Length = 477 Score = 171 bits (434), Expect = 7e-42 Identities = 95/258 (36%), Positives = 145/258 (56%), Gaps = 7/258 (2%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 + +G G+F++V + K G A+K + ++ R +E EIA +K I+H N+V L Sbjct: 27 EVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLEN---EIAVLKRIKHENIVTL 83 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 ++ S + Y+V++ V GGELFD+I+ G E +A Q+++AV Y H G+ HRD Sbjct: 84 EDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRD 143 Query: 566 LKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGM 736 LKPENLL + + ++DFGLS + + +G++ TACGTP YVAPEVLA K Y Sbjct: 144 LKPENLLYLTPEENSKIMITDFGLS----KMEQNGVMSTACGTPGYVAPEVLAQKPY-SK 198 Query: 737 AADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLIKRIL 904 A D WS G+I ++L+ GY PF + L++ I P W S A++ I +L Sbjct: 199 AVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLL 258 Query: 905 DPNPHTRITIAQILEDEW 958 + +P+ R T + L W Sbjct: 259 EKDPNERYTCEKALRHPW 276
>Q3SZW1:TSSK1_BOVIN Testis-specific serine/threonine-protein kinase 1 - Bos taurus| (Bovine) Length = 367 Score = 171 bits (432), Expect = 1e-41 Identities = 97/262 (37%), Positives = 148/262 (56%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y +G +GEGS+AKVK A R A+K++DR + + + REI + ++ H + Sbjct: 12 YIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPTDFLEKFLPREIEILAMLNHRS 71 Query: 374 VVQLHEVM-ASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 +++ +E+ S K+Y+V+E G+L + I G L ED+AR+ FHQL +A+ YCH Sbjct: 72 IIKTYEIFETSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDLD 131 Query: 551 VYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDG----LLHTACGTPNYVAPEVLAD 718 V HRDLK ENLLLD +K+SDFG S +DD L T CG+ Y APEVL Sbjct: 132 VVHRDLKCENLLLDKDFNIKLSDFGFS--KRCLRDDSGRLTLSKTFCGSAAYAAPEVLQG 189 Query: 719 KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP--PWFSTGARNLI 892 Y D+WS G+IL++++ G +P+DD N+ + ++ V+ P + ++LI Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 R+L P+ R+ I +IL W Sbjct: 250 YRMLQPDVTRRLHIDEILSHCW 271
>O96017:CHK2_HUMAN Serine/threonine-protein kinase Chk2 - Homo sapiens (Human)| Length = 543 Score = 169 bits (429), Expect = 3e-41 Identities = 107/305 (35%), Positives = 163/305 (53%), Gaps = 20/305 (6%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVE-----QIKREIATMKL 358 Y + KT+G G+ +VK+A + + AIK++ + E ++ EI +K Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279 Query: 359 IRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYC 538 + HP ++++ ++ Y+VLE +EGGELFDK+V + +L E + YF+Q++ AV Y Sbjct: 280 LNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYL 338 Query: 539 HSRGVYHRDLKPENLLLDSYG---ALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEV 709 H G+ HRDLKPEN+LL S +K++DFG S +T L+ T CGTP Y+APEV Sbjct: 339 HENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGET---SLMRTLCGTPTYLAPEV 395 Query: 710 LADKGYDG--MAADVWSCGIILFVLMAGYLPFDDPNLMTLYK---LISRANVSCPPW--F 868 L G G A D WS G+ILF+ ++GY PF + K + N W Sbjct: 396 LVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEV 455 Query: 869 STGARNLIKRILDPNPHTRITIAQI-----LEDEWFKKDYKPPLSEHNEDVSLEDVDAAF 1033 S A +L+K++L +P R T + L+DE K+ ++ LSE NE +L V A Sbjct: 456 SEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQP 515 Query: 1034 DSSEE 1048 +S + Sbjct: 516 STSRK 520
>P38991:IPL1_YEAST Spindle assembly checkpoint kinase - Saccharomyces cerevisiae| (Baker's yeast) Length = 367 Score = 169 bits (428), Expect = 4e-41 Identities = 77/259 (29%), Positives = 147/259 (56%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +ELGK +G+G F KV + G CA+KV+++ ++++ + +Q +RE+ + HPN Sbjct: 104 FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPN 163 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 + + + + ++Y+++E++ GE++ + G + A Y +Q+ NA+DY H + + Sbjct: 164 LTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNI 223 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPEN+L+ +K++DFG S +P + T CGT +Y++PE++ + YD Sbjct: 224 IHRDIKPENILIGFNNVIKLTDFGWSIINP---PENRRKTVCGTIDYLSPEMVESREYD- 279 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D W+ G++ F L+ G PF++ T YK I+ ++ P S A++LI ++L + Sbjct: 280 HTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYD 339 Query: 914 PHTRITIAQILEDEWFKKD 970 P R+ + + W ++ Sbjct: 340 PKDRMRLGDVKMHPWILRN 358
>P53681:CRK_DAUCA CDPK-related protein kinase - Daucus carota (Carrot)| Length = 602 Score = 169 bits (428), Expect = 4e-41 Identities = 104/278 (37%), Positives = 157/278 (56%), Gaps = 14/278 (5%) Frame = +2 Query: 194 YELGKTIGEGSFA---KVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMK-LI 361 +E+G+ +G G F + K K G A+KV+ + + +E ++RE+ ++ L Sbjct: 148 FEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIEDVRREVKILRALT 207 Query: 362 RHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVN-SGKLGEDEARRYFHQLINAVDYC 538 H N+VQ ++ + +Y+V+E EGGEL D+I++ GK ED+A+ Q++N V +C Sbjct: 208 GHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVAFC 267 Query: 539 HSRGVYHRDLKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEV 709 H +GV HRDLKPEN L D LK DFGLS + K D L+ G+ YVAPEV Sbjct: 268 HLQGVVHRDLKPENFLFKSKDEDSQLKAIDFGLSDY---VKPDERLNDIVGSAYYVAPEV 324 Query: 710 LADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSC--PPW--FSTG 877 L + Y ADVWS G+I ++L+ G PF +++ + +AN+S PPW S+ Sbjct: 325 L-HRSY-STEADVWSIGVISYILLCGSRPFWARTESGIFRAVLKANLSFDEPPWPSVSSE 382 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFK--KDYKPPL 985 A++ +KR+L+ +P R+T AQ L W K D K PL Sbjct: 383 AKDFVKRLLNKDPRKRMTAAQALCHSWIKNSNDIKFPL 420
>O59697:PPK25_SCHPO Serine/threonine-protein kinase ppk25 - Schizosaccharomyces pombe| (Fission yeast) Length = 423 Score = 169 bits (427), Expect = 5e-41 Identities = 97/256 (37%), Positives = 150/256 (58%), Gaps = 1/256 (0%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 KTIG GS KVK+ + G A+K++ + V +++RE +L+RHPN+ ++ Sbjct: 57 KTIGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTV-RVQREALLGRLLRHPNICRV 115 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 + + + + Y++ E+V GG+L + I+ GKL ED AR + QLINA+ Y H + HRD Sbjct: 116 IDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYLHKNFIVHRD 175 Query: 566 LKPENLLLDSYGA-LKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAA 742 LK EN+LL +K+ DFGLS F +KDD LL T CG+ + APE+L K Y G Sbjct: 176 LKIENVLLTQDSRQVKLIDFGLSNF--YSKDD-LLRTYCGSLYFAAPELLDAKPYIGPEV 232 Query: 743 DVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPNPHT 922 DVWS G++++V++ G +PFDD ++ L+ I + P + S +LI +L+ NP Sbjct: 233 DVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPSYISEDCCSLIAAMLNVNPRK 292 Query: 923 RITIAQILEDEWFKKD 970 R ++ Q + W KK+ Sbjct: 293 RCSLEQAAKFPWLKKN 308
>P16912:KDC2_DROME Protein kinase DC2 - Drosophila melanogaster (Fruit fly)| Length = 583 Score = 169 bits (427), Expect = 5e-41 Identities = 93/278 (33%), Positives = 154/278 (55%), Gaps = 14/278 (5%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ KT+G G+F +V + +D + CA+K+L V+R K +E +K E ++ IRHP Sbjct: 274 YQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPF 333 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 V+ L S +YM+ ++V GGELF + N+GK + Y ++++A++Y HS + Sbjct: 334 VISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQI 393 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL++ G LK++DFG F+ + +D T CGTP Y+APE++ KG++ Sbjct: 394 VYRDLKPENLLINRDGHLKITDFG---FAKKLRD--RTWTLCGTPEYIAPEIIQSKGHN- 447 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D W+ G++++ ++ GY PF D +Y+ I + A++LIK++L + Sbjct: 448 KAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVND 507 Query: 914 PHTRI-----TIAQILEDEWFK---------KDYKPPL 985 R+ + WFK K KPP+ Sbjct: 508 RTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPI 545
>Q9MZD9:KAPCA_SHEEP cAMP-dependent protein kinase, alpha-catalytic subunit - Ovis aries| (Sheep) Length = 351 Score = 169 bits (427), Expect = 5e-41 Identities = 88/237 (37%), Positives = 139/237 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K T G A+K+LD+ V++ K +E E ++ + P Sbjct: 44 FERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274
>Q6FV07:IPL1_CANGA Spindle assembly checkpoint kinase - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 358 Score = 169 bits (427), Expect = 5e-41 Identities = 77/259 (29%), Positives = 153/259 (59%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F KV + ++G CA+K +++N +L+ +++Q+KRE+ + HPN Sbjct: 100 FEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQLGMDHPN 159 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ + ++Y+++E GEL+ + N+G + A Y +Q+ +A+ Y H + + Sbjct: 160 IIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALHYMHKKRI 219 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPEN+L+ +K++DFG S +P + T CGT +Y++PE++ + YD Sbjct: 220 IHRDVKPENVLIGFDNVVKLADFGWSILNP---EGSKRKTLCGTIDYLSPEMITPREYDE 276 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 DVW+ G++ + L+ G PF++ + YK I + +++ P S A++LI ++L + Sbjct: 277 Q-VDVWALGVLAYELVVGVPPFEENSKELTYKRILKCDLNFPESISKDAKDLISKLLVTD 335 Query: 914 PHTRITIAQILEDEWFKKD 970 R+++ + W K+ Sbjct: 336 TTQRLSLTGVKTHPWILKN 354
>Q9N0X0:AURKB_PIG Serine/threonine-protein kinase 12 - Sus scrofa (Pig)| Length = 344 Score = 169 bits (427), Expect = 5e-41 Identities = 80/257 (31%), Positives = 147/257 (57%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A++ ++ A+KVL ++ + + + Q++REI ++HPN Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLQHPN 136 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ + +IY++LE+ GEL+ ++ E +L +A+ YCH + V Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKCRTFDEQRTATIMEELADALIYCHGKKV 196 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL G LK++DFG S +P + T CGT +Y+ PE++ + ++ Sbjct: 197 IHRDIKPENLLLGLQGELKIADFGWSVHAPSLR----RKTMCGTLDYLPPEMIEGRTHN- 251 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+W G++ + L+ G PF+ + Y+ I + ++ PP GA++LI ++L N Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIGKVDLKFPPSVPAGAQDLISKLLKHN 311 Query: 914 PHTRITIAQILEDEWFK 964 P R+ +AQ+ W + Sbjct: 312 PSDRLPLAQVSAHPWVR 328
>Q7YRC6:AURKB_BOVIN Serine/threonine-protein kinase 12 - Bos taurus (Bovine)| Length = 344 Score = 168 bits (425), Expect = 8e-41 Identities = 80/257 (31%), Positives = 148/257 (57%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A++ ++ A+KVL ++ + + + Q++REI ++HPN Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLQHPN 136 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ + +IY++LE+ GEL+ ++ S E +L +A+ YCH++ V Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELADALTYCHAKKV 196 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL G LK++DFG S +P + T CGT +Y+ PE++ + ++ Sbjct: 197 IHRDIKPENLLLGLRGELKIADFGWSVHAPSLR----RKTMCGTLDYLPPEMIEGRTHN- 251 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+W G++ + L+ G PF+ + Y+ I + ++ PP GA++ I ++L N Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPPSVPLGAQDFIYKLLKHN 311 Query: 914 PHTRITIAQILEDEWFK 964 P R+ +AQ+ W + Sbjct: 312 PSERLPLAQVSAHPWVR 328
>P34208:CHK1_SCHPO Serine/threonine-protein kinase chk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 496 Score = 167 bits (423), Expect = 1e-40 Identities = 132/480 (27%), Positives = 215/480 (44%), Gaps = 67/480 (13%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHK----MVEQIKREIATMKLI 361 Y +G+ IG G+FA V++ D N A+K +++ H ++ EI KL Sbjct: 10 YHIGREIGTGAFASVRLCYDD-NAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLC 68 Query: 362 R-HPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYC 538 H N++ + + ++VLEF +GG+LFDKI + ED A+ YF QL+ + + Sbjct: 69 NGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFM 128 Query: 539 HSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLAD 718 HS+GV HRDLKPEN+LLD G LK+SDFG ++ LL++ G+P Y APE+ Sbjct: 129 HSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEI--T 186 Query: 719 KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP---PW--FSTGAR 883 + YDG DVWSCGIILF L+ G P+D+ T L+ + P PW S GA Sbjct: 187 QQYDGSKVDVWSCGIILFALLLGNTPWDEAISNTGDYLLYKKQCERPSYHPWNLLSPGAY 246 Query: 884 NLIKRILDPNPHTRITIAQILEDEWFKKD--YKPPLSEHNEDVSL--------------- 1012 ++I +L +P R ++ +++ W ++ + V+L Sbjct: 247 SIITGMLRSDPFKRYSVKHVVQHPWLTSSTPFRTKNGNCADPVALASRLMLKLRIDLDKP 306 Query: 1013 -------EDVDAAFDSSEEHLVAERREKPESMNAFALISRSAGFN----LGNLFEK---- 1147 D+ F ++ +++ + + + +S+ N + + EK Sbjct: 307 RLASSRASQNDSGFSMTQPAFKKNDQKELDRVEVYGALSQPVQLNKNIDVTEILEKDPSL 366 Query: 1148 ----EMMGMVK----------------RETSFASQRTPQEIMSKIEEACGPLGFN----- 1252 E G +K R T F S+ + + I+ + ++ L + Sbjct: 367 SQFCENEGFIKRLAKKAKNFYEICPPERLTRFYSRASRETIIDHLYDSLRLLAISVTMKY 426 Query: 1253 VRKQNYKMKLKGDKTGRKGHLSVATEVFEVAPSLHMVELRKTGGDTLEFHSFYQNFSSEL 1432 VR Q DK RK L E+ + +L ++ K GD LE+ F++N S + Sbjct: 427 VRNQTILYVNLHDK--RKCLLQGVIELTNLGHNLELINFIKRNGDPLEWRKFFKNVVSSI 484
>P28583:CDPK_SOYBN Calcium-dependent protein kinase SK5 - Glycine max (Soybean)| Length = 508 Score = 167 bits (423), Expect = 1e-40 Identities = 100/272 (36%), Positives = 145/272 (53%), Gaps = 9/272 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMK-LIRHP 370 YE+G+ +G+G F +G A K + + +L + E + REI M L H Sbjct: 34 YEVGRKLGQGQFGTTFECTRRASGGKFACKSIPKRKLLCKEDYEDVWREIQIMHHLSEHA 93 Query: 371 NVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 NVV++ + +++V+E EGGELFD+IV G E +A R ++ V+ CHS G Sbjct: 94 NVVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKTIVEVVEACHSLG 153 Query: 551 VYHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 V HRDLKPEN L D+ LK +DFGLS F K G+P YVAPEVL + Sbjct: 154 VMHRDLKPENFLFDTIDEDAKLKATDFGLSVF---YKPGESFCDVVGSPYYVAPEVL--R 208 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPF---DDPNLMTLYKLISRANVSCPPW--FSTGARN 886 G +DVWS G+IL++L++G PF +P + L+ + + PW S A++ Sbjct: 209 KLYGPESDVWSAGVILYILLSGVPPFWAESEPGIFRQI-LLGKLDFHSEPWPSISDSAKD 267 Query: 887 LIKRILDPNPHTRITIAQILEDEWFKKDYKPP 982 LI+++LD NP TR+T ++L W D P Sbjct: 268 LIRKMLDQNPKTRLTAHEVLRHPWIVDDNIAP 299
>Q00168:KCC2A_DROME Calcium/calmodulin-dependent protein kinase type II alpha chain -| Drosophila melanogaster (Fruit fly) Length = 530 Score = 167 bits (422), Expect = 2e-40 Identities = 97/262 (37%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ + +G+G+F+ VK G A K+++ L + ++++RE + + HPN Sbjct: 14 YDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKK-LTARDFQKLEREARICRKLHHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ + ++ Y+V + V GGELF+ IV E +A Q++ +V++CH GV Sbjct: 73 IVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGV 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKAKGAAVKLADFGL-AIEVQGDHQAWFGFA-GTPGYLSPEVLKKEP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G + D+W+CG+IL++L+ GY PF D + LY I + P W + A+NLI Sbjct: 191 Y-GKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP+ RIT A+ L+ W Sbjct: 250 NQMLTVNPNKRITAAEALKHPW 271
>P36887:KAPCA_PIG cAMP-dependent protein kinase, alpha-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 167 bits (422), Expect = 2e-40 Identities = 87/237 (36%), Positives = 138/237 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K G A+K+LD+ V++ K +E E ++ + P Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 104 LVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274
>Q96GD4:AURKB_HUMAN Serine/threonine-protein kinase 12 - Homo sapiens (Human)| Length = 344 Score = 167 bits (422), Expect = 2e-40 Identities = 81/257 (31%), Positives = 147/257 (57%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G+ +G+G F V +A++ ++ A+KVL ++ + + + Q++REI + HPN Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPN 136 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ + +IY++LE+ GEL+ ++ S E +L +A+ YCH + V Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKV 196 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLLL G LK++DFG S +P + T CGT +Y+ PE++ + ++ Sbjct: 197 IHRDIKPENLLLGLKGELKIADFGWSVHAPSLR----RKTMCGTLDYLPPEMIEGRMHN- 251 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+W G++ + L+ G PF+ + Y+ I + ++ P TGA++LI ++L N Sbjct: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN 311 Query: 914 PHTRITIAQILEDEWFK 964 P R+ +AQ+ W + Sbjct: 312 PSERLPLAQVSAHPWVR 328
>O88831:KKCC2_RAT Calcium/calmodulin-dependent protein kinase kinase 2 - Rattus| norvegicus (Rat) Length = 587 Score = 166 bits (421), Expect = 2e-40 Identities = 104/317 (32%), Positives = 167/317 (52%), Gaps = 30/317 (9%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHK------------------- 316 Y L IG+GS+ VK+A + + A+KVL + ++R Sbjct: 164 YTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCI 223 Query: 317 ----MVEQIKREIATMKLIRHPNVVQLHEVM--ASKSKIYMVLEFVEGGELFDKIVNSGK 478 +EQ+ +EIA +K + HPNVV+L EV+ ++ +YMV E V G + + + Sbjct: 224 QPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPTLKP 282 Query: 479 LGEDEARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDD 658 L ED+AR YF LI ++Y H + + HRD+KP NLL+ G +K++DFG+S + D Sbjct: 283 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVS--NEFKGSD 340 Query: 659 GLLHTACGTPNYVAPEVLAD--KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKL 832 LL GTP ++APE L++ K + G A DVW+ G+ L+ + G PF D +M L+ Sbjct: 341 ALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSK 400 Query: 833 ISRANVSCP--PWFSTGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDV 1006 I + P P + ++LI R+LD NP +RI + +I W + PL +E+ Sbjct: 401 IKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENC 460 Query: 1007 SLEDV-DAAFDSSEEHL 1054 +L +V + ++S +H+ Sbjct: 461 TLVEVTEEEVENSVKHI 477
>Q8C078:KKCC2_MOUSE Calcium/calmodulin-dependent protein kinase kinase 2 - Mus musculus| (Mouse) Length = 588 Score = 166 bits (421), Expect = 2e-40 Identities = 104/317 (32%), Positives = 167/317 (52%), Gaps = 30/317 (9%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHK------------------- 316 Y L IG+GS+ VK+A + + A+KVL + ++R Sbjct: 165 YTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGARPAPGGCI 224 Query: 317 ----MVEQIKREIATMKLIRHPNVVQLHEVM--ASKSKIYMVLEFVEGGELFDKIVNSGK 478 +EQ+ +EIA +K + HPNVV+L EV+ ++ +YMV E V G + + + Sbjct: 225 QPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPTLKP 283 Query: 479 LGEDEARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDD 658 L ED+AR YF LI ++Y H + + HRD+KP NLL+ G +K++DFG+S + D Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVS--NEFKGSD 341 Query: 659 GLLHTACGTPNYVAPEVLAD--KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKL 832 LL GTP ++APE L++ K + G A DVW+ G+ L+ + G PF D +M L+ Sbjct: 342 ALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSK 401 Query: 833 ISRANVSCP--PWFSTGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDV 1006 I + P P + ++LI R+LD NP +RI + +I W + PL +E+ Sbjct: 402 IKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENC 461 Query: 1007 SLEDV-DAAFDSSEEHL 1054 +L +V + ++S +H+ Sbjct: 462 TLVEVTEEEVENSVKHI 478
>Q96RR4:KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase kinase 2 - Homo sapiens| (Human) Length = 588 Score = 166 bits (421), Expect = 2e-40 Identities = 104/317 (32%), Positives = 167/317 (52%), Gaps = 30/317 (9%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHK------------------- 316 Y L IG+GS+ VK+A + + A+KVL + ++R Sbjct: 165 YTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCI 224 Query: 317 ----MVEQIKREIATMKLIRHPNVVQLHEVM--ASKSKIYMVLEFVEGGELFDKIVNSGK 478 +EQ+ +EIA +K + HPNVV+L EV+ ++ +YMV E V G + + + Sbjct: 225 QPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPTLKP 283 Query: 479 LGEDEARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDD 658 L ED+AR YF LI ++Y H + + HRD+KP NLL+ G +K++DFG+S + D Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVS--NEFKGSD 341 Query: 659 GLLHTACGTPNYVAPEVLAD--KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKL 832 LL GTP ++APE L++ K + G A DVW+ G+ L+ + G PF D +M L+ Sbjct: 342 ALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSK 401 Query: 833 ISRANVSCP--PWFSTGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDV 1006 I + P P + ++LI R+LD NP +RI + +I W + PL +E+ Sbjct: 402 IKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENC 461 Query: 1007 SLEDV-DAAFDSSEEHL 1054 +L +V + ++S +H+ Sbjct: 462 TLVEVTEEEVENSVKHI 478
>P17612:KAPCA_HUMAN cAMP-dependent protein kinase, alpha-catalytic subunit - Homo| sapiens (Human) Length = 351 Score = 166 bits (421), Expect = 2e-40 Identities = 87/237 (36%), Positives = 138/237 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K G A+K+LD+ V++ K +E E ++ + P Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274
>Q8MJ44:KAPCA_CANFA cAMP-dependent protein kinase, alpha-catalytic subunit - Canis| familiaris (Dog) Length = 350 Score = 166 bits (421), Expect = 2e-40 Identities = 87/237 (36%), Positives = 138/237 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K G A+K+LD+ V++ K +E E ++ + P Sbjct: 43 FERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 102 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 103 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 162 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 163 IYRDLKPENLLIDQQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 216 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L Sbjct: 217 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>P00517:KAPCA_BOVIN cAMP-dependent protein kinase, alpha-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 166 bits (421), Expect = 2e-40 Identities = 87/237 (36%), Positives = 138/237 (58%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K G A+K+LD+ V++ K +E E ++ + P Sbjct: 44 FERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274
>P27791:KAPCA_RAT cAMP-dependent protein kinase, alpha-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 166 bits (420), Expect = 3e-40 Identities = 86/233 (36%), Positives = 137/233 (58%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 KT+G GSF +V + K +G A+K+LD+ V++ K +E E ++ + P +V+L Sbjct: 48 KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + +RD Sbjct: 108 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167 Query: 566 LKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAAD 745 LKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ A D Sbjct: 168 LKPENLLIDQQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVD 221 Query: 746 VWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274
>P05132:KAPCA_MOUSE cAMP-dependent protein kinase, alpha-catalytic subunit - Mus| musculus (Mouse) Length = 351 Score = 166 bits (420), Expect = 3e-40 Identities = 86/233 (36%), Positives = 137/233 (58%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 KT+G GSF +V + K +G A+K+LD+ V++ K +E E ++ + P +V+L Sbjct: 48 KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + +RD Sbjct: 108 EFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167 Query: 566 LKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAAD 745 LKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ A D Sbjct: 168 LKPENLLIDQQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVD 221 Query: 746 VWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274
>Q7TPS0:KS6A6_MOUSE Ribosomal protein S6 kinase alpha-6 - Mus musculus (Mouse)| Length = 764 Score = 166 bits (419), Expect = 4e-40 Identities = 102/291 (35%), Positives = 159/291 (54%), Gaps = 12/291 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YEL + IG GS++ K + + A+K++D+N + E+I+ M+ +HPN Sbjct: 446 YELKEDIGIGSYSVCKRCIHSASNVEFAVKIIDKN---KRDPSEEIE---ILMRYGQHPN 499 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ L EV +Y+V + ++GGEL D+I+ E EA + + V+ HS+GV Sbjct: 500 IISLKEVFDDGKYVYLVTDLMKGGELLDRILKKKCFSEQEASNVLYVITKTVECLHSQGV 559 Query: 554 YHRDLKPENLLLDSYGA----LKVSDFGLSAFSPQTK-DDGLLHTACGTPNYVAPEVLAD 718 HRDLKP N+L A +K+ DFG F+ Q + ++GLL T C T N+VAPEVL Sbjct: 560 VHRDLKPSNILYMDESAHPDSIKICDFG---FAKQLRGENGLLLTPCYTANFVAPEVLTQ 616 Query: 719 KGYDGMAADVWSCGIILFVLMAGYLPF-----DDPNLMTLYKLISRANVSCPPW--FSTG 877 +GYD A D+WS G++L+ ++AGY PF D P + L R ++S W S G Sbjct: 617 QGYDA-ACDIWSLGVLLYTMLAGYTPFSNGPNDTPEEILLRIGNGRFSLSGGIWDNISRG 675 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAA 1030 A++L+ +L +PH R T Q+L+ W + + P + N D ++ AA Sbjct: 676 AKDLLSHMLHMDPHQRYTAEQVLKHPWITQREQLPRHQPNSDEPPQEAVAA 726 Score = 149 bits (376), Expect = 4e-35 Identities = 85/279 (30%), Positives = 157/279 (56%), Gaps = 16/279 (5%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRN---GATCAIKVLDRNHV-LRHKMVEQIKREIATMKLI 361 ++L K +G+GSF KV + + G A+KVL + + +R ++ +++R+I + Sbjct: 93 FDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLRKASLKVRDRVRTKMERDILVE--V 150 Query: 362 RHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCH 541 HP +V+LH ++ K+Y++L+F+ GG++F ++ E++ + Y +L A+D+ H Sbjct: 151 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 210 Query: 542 SRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 G+ +RDLKPEN+LLD G +K++DFGLS S + ++ CGT Y+APEV+ + Sbjct: 211 RLGIVYRDLKPENILLDEIGHIKLTDFGLSKES--VDQEKKAYSFCGTVEYMAPEVVNRR 268 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRI 901 + +AD WS G+++F ++ G LPF + +I +A + P + S A++L++ + Sbjct: 269 AH-SQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRML 327 Query: 902 LDPNPHTRI------------TIAQILEDEWFKKDYKPP 982 NP R+ A I ++ +K++ +PP Sbjct: 328 FKRNPANRLGSEGVEEVKRHAFFASIDWNKLYKREVQPP 366
>P42818:KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 - Arabidopsis thaliana| (Mouse-ear cress) Length = 465 Score = 166 bits (419), Expect = 4e-40 Identities = 89/263 (33%), Positives = 150/263 (57%), Gaps = 6/263 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+ K +G+G+F KV + A+KV+ ++H++ E +K E + I HP Sbjct: 134 FEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPF 193 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +VQL +K ++Y+VL+F+ GG LF ++ + G ED AR Y ++++AV + H +G+ Sbjct: 194 IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 253 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLS-AFSPQTKDDGLLHTACGTPNYVAPEVLADKGYD 730 HRDLKPEN+L+D+ G + ++DFGL+ F T+ + + CGT Y+APE++ KG+D Sbjct: 254 MHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSM----CGTTEYMAPEIVRGKGHD 309 Query: 731 GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDP 910 AAD WS GI+L+ ++ G PF K++ + + P + S A ++K +L Sbjct: 310 -KAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIV-KDKIKLPQFLSNEAHAILKGLLQK 367 Query: 911 NPHTRI-----TIAQILEDEWFK 964 P R+ +I + +WFK Sbjct: 368 EPERRLGSGLSGAEEIKQHKWFK 390
>P22694:KAPCB_HUMAN cAMP-dependent protein kinase, beta-catalytic subunit - Homo| sapiens (Human) Length = 351 Score = 166 bits (419), Expect = 4e-40 Identities = 90/261 (34%), Positives = 145/261 (55%), Gaps = 5/261 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K A+K+LD+ V++ K +E E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L + Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 914 PHTRI-----TIAQILEDEWF 961 R ++ I +WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P25321:KAPCA_CRIGR cAMP-dependent protein kinase, alpha-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 166 bits (419), Expect = 4e-40 Identities = 86/233 (36%), Positives = 136/233 (58%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 KT+G GSF +V + K G A+K+LD+ V++ K +E E ++ + P +V+L Sbjct: 48 KTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + +RD Sbjct: 108 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167 Query: 566 LKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAAD 745 LKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ A D Sbjct: 168 LKPENLLIDQQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN-KAVD 221 Query: 746 VWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274
>P24256:KAPB2_BOVIN cAMP-dependent protein kinase, beta-2-catalytic subunit - Bos| taurus (Bovine) Length = 397 Score = 166 bits (419), Expect = 4e-40 Identities = 90/261 (34%), Positives = 145/261 (55%), Gaps = 5/261 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K A+K+LD+ V++ K +E E ++ + P Sbjct: 90 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 149 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 150 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 209 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 210 IYRDLKPENLLIDHQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 263 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L + Sbjct: 264 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 323 Query: 914 PHTRI-----TIAQILEDEWF 961 R ++ I +WF Sbjct: 324 LTKRFGNLKNGVSDIKTHKWF 344
>P05131:KAPB1_BOVIN cAMP-dependent protein kinase, beta-1-catalytic subunit - Bos| taurus (Bovine) Length = 351 Score = 166 bits (419), Expect = 4e-40 Identities = 90/261 (34%), Positives = 145/261 (55%), Gaps = 5/261 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K A+K+LD+ V++ K +E E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L + Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 914 PHTRI-----TIAQILEDEWF 961 R ++ I +WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P68182:KAPCB_RAT cAMP-dependent protein kinase, beta-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 165 bits (417), Expect = 7e-40 Identities = 90/261 (34%), Positives = 145/261 (55%), Gaps = 5/261 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K A+K+LD+ V++ K +E E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L + Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 914 PHTRI-----TIAQILEDEWF 961 R ++ I +WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P68181:KAPCB_MOUSE cAMP-dependent protein kinase, beta-catalytic subunit - Mus| musculus (Mouse) Length = 351 Score = 165 bits (417), Expect = 7e-40 Identities = 90/261 (34%), Positives = 145/261 (55%), Gaps = 5/261 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K A+K+LD+ V++ K +E E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L + Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 914 PHTRI-----TIAQILEDEWF 961 R ++ I +WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P68180:KAPCB_CRIGR cAMP-dependent protein kinase, beta-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 165 bits (417), Expect = 7e-40 Identities = 90/261 (34%), Positives = 145/261 (55%), Gaps = 5/261 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K A+K+LD+ V++ K +E E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 104 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L + Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 914 PHTRI-----TIAQILEDEWF 961 R ++ I +WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>Q924X7:STK33_MOUSE Serine/threonine-protein kinase 33 - Mus musculus (Mouse)| Length = 491 Score = 164 bits (416), Expect = 9e-40 Identities = 91/268 (33%), Positives = 150/268 (55%), Gaps = 13/268 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y G+ +G+GSF V A D GA AIK +++ M + ++RE++ +K + H + Sbjct: 111 YTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSSAM-KLLEREVSILKTVNHQH 169 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ L +V S K+Y+V+E E GEL + G E+E R L +A+ Y H++ + Sbjct: 170 IIHLEQVFESPQKMYLVMELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKDI 229 Query: 554 YHRDLKPENLLLDSYGA---------LKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPE 706 HRDLK EN+++ S +KV+DFGLS ++ +G++ T CGTP Y+APE Sbjct: 230 VHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPE 289 Query: 707 VLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANV--SCPPW--FST 874 V+ Y D+WS G+I+F+L+ G PF + LY+LI + + P W S Sbjct: 290 VINAHDY-SQQCDIWSIGVIMFILLCGEPPFLANSEEKLYELIKKGELRFENPVWESVSD 348 Query: 875 GARNLIKRILDPNPHTRITIAQILEDEW 958 A+N +K+++ +P RIT ++L+++W Sbjct: 349 SAKNTLKQLMKVDPAHRITAKELLDNQW 376
>P05383:KAPCB_PIG cAMP-dependent protein kinase, beta-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 164 bits (416), Expect = 9e-40 Identities = 90/261 (34%), Positives = 145/261 (55%), Gaps = 5/261 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + K A+K+LD+ V++ K +E E ++ + P Sbjct: 44 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +YMV+E+V GGE+F + G+ E AR Y Q++ +Y HS + Sbjct: 104 LVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+D G ++V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IYRDLKPENLLIDHQGYIQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D W+ G++++ + AGY PF + +Y+ I V P FS+ ++L++ +L + Sbjct: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 Query: 914 PHTRI-----TIAQILEDEWF 961 R ++ I +WF Sbjct: 278 LTKRFGNLKNGVSDIKTHKWF 298
>P12370:KAPC_DROME cAMP-dependent protein kinase catalytic subunit - Drosophila| melanogaster (Fruit fly) Length = 353 Score = 164 bits (414), Expect = 2e-39 Identities = 92/261 (35%), Positives = 145/261 (55%), Gaps = 5/261 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E KT+G GSF +V + + A+K+LD+ V++ K VE E ++ I+ P Sbjct: 46 FERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPF 105 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V L S +YMVLE+V GGE+F + G+ E +R Y Q++ A +Y H + Sbjct: 106 LVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDL 165 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 +RDLKPENLL+DS G LKV+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 166 IYRDLKPENLLIDSQGYLKVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 219 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D W+ G++++ + AGY PF + +Y+ I V P F + ++L++ +L + Sbjct: 220 KAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVD 279 Query: 914 -----PHTRITIAQILEDEWF 961 + + + I +WF Sbjct: 280 LTKRYGNLKAGVNDIKNQKWF 300
>Q5ZKI0:KCC2D_CHICK Calcium/calmodulin-dependent protein kinase type II delta chain -| Gallus gallus (Chicken) Length = 479 Score = 163 bits (413), Expect = 2e-39 Identities = 95/262 (36%), Positives = 152/262 (58%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKITTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q + A GTP Y++PEVL Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGL-AIEVQGEQQAWFGFA-GTPGYLSPEVLRKDP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT ++ L+ W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>P27466:KCC1_YEAST Calcium/calmodulin-dependent protein kinase I - Saccharomyces| cerevisiae (Baker's yeast) Length = 446 Score = 163 bits (413), Expect = 2e-39 Identities = 94/265 (35%), Positives = 145/265 (54%), Gaps = 10/265 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKM-VEQIKREIATMKLIRHP 370 Y GKT+G G+F V+ AK+T G A+K+L + + +K+ +E + E+ ++ + HP Sbjct: 37 YVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHP 96 Query: 371 NVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 N+V + SK K Y++ + +GGELFD+I+ GK E++A R ++++AV Y HS+ Sbjct: 97 NIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQN 156 Query: 551 VYHRDLKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 + HRDLKPENLL L V+DFG++ D+ LL+ G+ YVAPEVL Sbjct: 157 IVHRDLKPENLLYIDKSDESPLVVADFGIA--KRLKSDEELLYKPAGSLGYVAPEVLTQD 214 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSC----PPW--FSTGAR 883 G+ G D+WS G+I + L+ GY F + + P W S A+ Sbjct: 215 GH-GKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAK 273 Query: 884 NLIKRILDPNPHTRITIAQILEDEW 958 I + L+ +P R T A++LED W Sbjct: 274 QFILKALNLDPSKRPTAAELLEDPW 298
>Q6BVA0:IPL1_DEBHA Spindle assembly checkpoint kinase - Debaryomyces hansenii (Yeast)| (Torulaspora hansenii) Length = 412 Score = 163 bits (413), Expect = 2e-39 Identities = 81/255 (31%), Positives = 144/255 (56%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+GK +G+G KV K +G A+KV+ + ++ K+ + +REI + HP Sbjct: 148 FEIGKVLGKGKLGKVYCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIEIQSNLIHPK 207 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 + +L+ +Y++LE+ GEL+ + + + A Y +Q+ A+DY H++ + Sbjct: 208 ISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALDYLHTKHI 267 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPEN+LL + +K+SDFG S S + L T CGT +Y+ PE++ +D Sbjct: 268 IHRDIKPENILLSTDNCIKLSDFGWSVKSLPSSSTKRL-TICGTLDYLPPEMIESNEHD- 325 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 D+WS GI+ + + G PF++ + + YK I++ ++ P + S+ A +LI R+L + Sbjct: 326 YTVDIWSLGILCYEFLVGKPPFEEIDKNSTYKRIAKVDLKIPSFLSSEATDLILRLLQKS 385 Query: 914 PHTRITIAQILEDEW 958 P RIT+A+++ W Sbjct: 386 PKKRITLAEVMNHPW 400
>O00444:PLK4_HUMAN Serine/threonine-protein kinase PLK4 - Homo sapiens (Human)| Length = 970 Score = 163 bits (412), Expect = 3e-39 Identities = 90/285 (31%), Positives = 153/285 (53%), Gaps = 3/285 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++G +G+GSFA V A+ G AIK++D+ + + MV++++ E+ ++HP+ Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGK-LGEDEARRYFHQLINAVDYCHSRG 550 +++L+ + +Y+VLE GE+ + N K E+EAR + HQ+I + Y HS G Sbjct: 72 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG 131 Query: 551 VYHRDLKPENLLLDSYGALKVSDFGLSA--FSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 + HRDL NLLL +K++DFGL+ P K +T CGTPNY++PE+ A + Sbjct: 132 ILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKH----YTLCGTPNYISPEI-ATRS 186 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 G+ +DVWS G + + L+ G PFD + + A+ P + S A++LI ++L Sbjct: 187 AHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLL 246 Query: 905 DPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDS 1039 NP R++++ +L+ P N +D+ DS Sbjct: 247 RRNPADRLSLSSVLDH---------PFMSRNSSTKSKDLGTVEDS 282
>P11275:KCC2A_RAT Calcium/calmodulin-dependent protein kinase type II alpha chain -| Rattus norvegicus (Rat) Length = 478 Score = 163 bits (412), Expect = 3e-39 Identities = 96/262 (36%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 71 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y++ + V GGELF+ IV E +A Q++ AV +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A + + A GTP Y++PEVL Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGL-AIEVEGEQQAWFGFA-GTPGYLSPEVLRKDP 189 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT A+ L+ W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>Q5RCC4:KCC2A_PONPY Calcium/calmodulin-dependent protein kinase type II alpha chain -| Pongo pygmaeus (Orangutan) Length = 478 Score = 163 bits (412), Expect = 3e-39 Identities = 96/262 (36%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 71 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y++ + V GGELF+ IV E +A Q++ AV +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A + + A GTP Y++PEVL Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGL-AIEVEGEQQAWFGFA-GTPGYLSPEVLRKDP 189 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT A+ L+ W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>P11798:KCC2A_MOUSE Calcium/calmodulin-dependent protein kinase type II alpha chain -| Mus musculus (Mouse) Length = 478 Score = 163 bits (412), Expect = 3e-39 Identities = 96/262 (36%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 71 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y++ + V GGELF+ IV E +A Q++ AV +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A + + A GTP Y++PEVL Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGL-AIEVEGEQQAWFGFA-GTPGYLSPEVLRKDP 189 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT A+ L+ W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>Q9UQM7:KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II alpha chain -| Homo sapiens (Human) Length = 478 Score = 163 bits (412), Expect = 3e-39 Identities = 96/262 (36%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 71 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y++ + V GGELF+ IV E +A Q++ AV +CH GV Sbjct: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 131 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A + + A GTP Y++PEVL Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGL-AIEVEGEQQAWFGFA-GTPGYLSPEVLRKDP 189 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT A+ L+ W Sbjct: 249 NKMLTINPSKRITAAEALKHPW 270
>O88764:DAPK3_RAT Death-associated protein kinase 3 - Rattus norvegicus (Rat)| Length = 448 Score = 163 bits (412), Expect = 3e-39 Identities = 97/270 (35%), Positives = 154/270 (57%), Gaps = 13/270 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHV---LRHKMVEQIKREIATMKLIR 364 YE+G+ +G G FA V+ + G A K + + + R E+I+RE++ ++ IR Sbjct: 13 YEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIR 72 Query: 365 HPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHS 544 HPN++ LH+V +K+ + ++LE V GGELFD + L EDEA ++ Q+++ V Y HS Sbjct: 73 HPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132 Query: 545 RGVYHRDLKPEN-LLLDSYGA---LKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVL 712 + + H DLKPEN +LLD + A +K+ DFG+ + + + GTP +VAPE++ Sbjct: 133 KRIAHFDLKPENIMLLDKHAASPRIKLIDFGI---AHRIEAGSEFKNIFGTPEFVAPEIV 189 Query: 713 ADKGYD--GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSC-PPWFSTG-- 877 Y+ G+ AD+WS G+I ++L++G PF IS N +FS+ Sbjct: 190 ---NYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSE 246 Query: 878 -ARNLIKRILDPNPHTRITIAQILEDEWFK 964 A++ I+R+L +P R+TIAQ LE W K Sbjct: 247 LAKDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>O54784:DAPK3_MOUSE Death-associated protein kinase 3 - Mus musculus (Mouse)| Length = 448 Score = 163 bits (412), Expect = 3e-39 Identities = 97/270 (35%), Positives = 154/270 (57%), Gaps = 13/270 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHV---LRHKMVEQIKREIATMKLIR 364 YE+G+ +G G FA V+ + G A K + + + R E+I+RE++ ++ IR Sbjct: 13 YEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIR 72 Query: 365 HPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHS 544 HPN++ LH+V +K+ + ++LE V GGELFD + L EDEA ++ Q+++ V Y HS Sbjct: 73 HPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132 Query: 545 RGVYHRDLKPEN-LLLDSYGA---LKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVL 712 + + H DLKPEN +LLD + A +K+ DFG+ + + + GTP +VAPE++ Sbjct: 133 KRIAHFDLKPENIMLLDKHAASPRIKLIDFGI---AHRIEAGSEFKNIFGTPEFVAPEIV 189 Query: 713 ADKGYD--GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSC-PPWFSTG-- 877 Y+ G+ AD+WS G+I ++L++G PF IS N +FS+ Sbjct: 190 ---NYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSE 246 Query: 878 -ARNLIKRILDPNPHTRITIAQILEDEWFK 964 A++ I+R+L +P R+TIAQ LE W K Sbjct: 247 LAKDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>Q7RJG2:CDPK4_PLAYO Calcium-dependent protein kinase 4 - Plasmodium yoelii yoelii| Length = 528 Score = 163 bits (412), Expect = 3e-39 Identities = 112/396 (28%), Positives = 196/396 (49%), Gaps = 11/396 (2%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 K +G+GSF +V ++KD G AIKV+ + HV R + + RE+ +K++ H N+++L Sbjct: 74 KILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIMKL 133 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 +E + Y+V + GGELFD+I++ + E +A R Q+++ + Y H V HRD Sbjct: 134 YEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVHRD 193 Query: 566 LKPENLLLDSYG----ALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 LKPEN+LL++ +K+ DFGLS +K + GT Y+AP+VL G Sbjct: 194 LKPENILLETKNKEDMIIKIIDFGLSTHFEYSKK---MKDKIGTAYYIAPDVL--HGTYD 248 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP-PWF---STGARNLIKRI 901 D+WSCG+IL++L++G PF+ N + K + + P F S A++LIK++ Sbjct: 249 EKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAKDLIKKM 308 Query: 902 LDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREKPE 1081 L RI+ LE EW + S+ N ++ + ++ + + ++ ++ Sbjct: 309 LMYTSAVRISARDALEHEWIRL----MTSKDNVNIDIPSLELSITNIKQFQSTQK----- 359 Query: 1082 SMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEE-ACGPLGFNVR 1258 L + ++ M + T+ + +I K+++ G L N Sbjct: 360 ------------------LAQAALLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNEL 401 Query: 1259 KQNYK--MKLKGDKTGRKGHLSVATEVFEVAPSLHM 1360 YK +KLKGD T + ++ EV ++ S+ + Sbjct: 402 IIGYKELLKLKGDDTTDLDNAAIEVEVDQILSSIDL 437
>P62345:CDPK4_PLABA Calcium-dependent protein kinase 4 - Plasmodium berghei (strain Anka)| Length = 528 Score = 163 bits (412), Expect = 3e-39 Identities = 112/396 (28%), Positives = 196/396 (49%), Gaps = 11/396 (2%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 K +G+GSF +V ++KD G AIKV+ + HV R + + RE+ +K++ H N+++L Sbjct: 74 KILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIMKL 133 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 +E + Y+V + GGELFD+I++ + E +A R Q+++ + Y H V HRD Sbjct: 134 YEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVHRD 193 Query: 566 LKPENLLLDSYG----ALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 LKPEN+LL++ +K+ DFGLS +K + GT Y+AP+VL G Sbjct: 194 LKPENILLETKNKEDMIIKIIDFGLSTHFEYSKK---MKDKIGTAYYIAPDVL--HGTYD 248 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP-PWF---STGARNLIKRI 901 D+WSCG+IL++L++G PF+ N + K + + P F S A++LIK++ Sbjct: 249 EKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAKDLIKKM 308 Query: 902 LDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREKPE 1081 L RI+ LE EW + S+ N ++ + ++ + + ++ ++ Sbjct: 309 LMYTSAVRISARDALEHEWIRL----MTSKDNVNIDIPSLELSITNIKQFQSTQK----- 359 Query: 1082 SMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEE-ACGPLGFNVR 1258 L + ++ M + T+ + +I K+++ G L N Sbjct: 360 ------------------LAQAALLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNEL 401 Query: 1259 KQNYK--MKLKGDKTGRKGHLSVATEVFEVAPSLHM 1360 YK +KLKGD T + ++ EV ++ S+ + Sbjct: 402 IIGYKELLKLKGDDTTDLDNAAIEVEVDQILSSIDL 437
>Q6SA08:TSSK4_HUMAN Testis-specific serine/threonine-protein kinase 4 - Homo sapiens| (Human) Length = 328 Score = 162 bits (411), Expect = 3e-39 Identities = 99/301 (32%), Positives = 158/301 (52%), Gaps = 15/301 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+GK IG GS+ V A T+ A+K++ + + + + REI MK++RH Sbjct: 25 YEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKY 84 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ + + S S++Y++LE +GG++ + I G E A ++F QL + Y HS+ + Sbjct: 85 LINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSI 144 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDG-------------LLHTACGTPNY 694 HRDLK ENLLLD + +K+SDFG + P + G L T CG+ Y Sbjct: 145 VHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAY 204 Query: 695 VAPEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPP--WF 868 PE+L Y+ +D WS G+IL+ L+ +LPFDD NL L + ++ V+ P Sbjct: 205 ACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLR-ETQKEVTFPANHTI 263 Query: 869 STGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEE 1048 S +NLI ++L R TI I++D W K ++P H E LE + +++++ Sbjct: 264 SQECKNLILQML-RQATKRATILDIIKDSWVLK-FQPEQPTH-EIRLLEAMCQLHNTTKQ 320 Query: 1049 H 1051 H Sbjct: 321 H 321
>P15791:KCC2D_RAT Calcium/calmodulin-dependent protein kinase type II delta chain -| Rattus norvegicus (Rat) Length = 533 Score = 162 bits (410), Expect = 5e-39 Identities = 95/262 (36%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKDP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT ++ L+ W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>O77708:KCC2D_RABIT Calcium/calmodulin-dependent protein kinase type II delta chain -| Oryctolagus cuniculus (Rabbit) Length = 533 Score = 162 bits (410), Expect = 5e-39 Identities = 95/262 (36%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKDP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT ++ L+ W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q95266:KCC2D_PIG Calcium/calmodulin-dependent protein kinase type II delta chain -| Sus scrofa (Pig) Length = 499 Score = 162 bits (410), Expect = 5e-39 Identities = 95/262 (36%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKDP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT ++ L+ W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q6PHZ2:KCC2D_MOUSE Calcium/calmodulin-dependent protein kinase type II delta chain -| Mus musculus (Mouse) Length = 499 Score = 162 bits (410), Expect = 5e-39 Identities = 95/262 (36%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKDP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT ++ L+ W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q13557:KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II delta chain -| Homo sapiens (Human) Length = 499 Score = 162 bits (410), Expect = 5e-39 Identities = 95/262 (36%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKDP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT ++ L+ W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>Q2HJF7:KCC2D_BOVIN Calcium/calmodulin-dependent protein kinase type II delta chain -| Bos taurus (Bovine) Length = 488 Score = 162 bits (410), Expect = 5e-39 Identities = 95/262 (36%), Positives = 151/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ +V++CH G+ Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKDP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 191 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT ++ L+ W Sbjct: 250 NKMLTINPAKRITASEALKHPW 271
>P40376:KAPB_SCHPO cAMP-dependent protein kinase catalytic subunit -| Schizosaccharomyces pombe (Fission yeast) Length = 512 Score = 162 bits (410), Expect = 5e-39 Identities = 88/233 (37%), Positives = 135/233 (57%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 +T+G GSF +V + + N AIKVL++ ++ K +E E + ++HP + L Sbjct: 205 QTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILSRVQHPFITIL 264 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 ++MV++F EGGELF + + E A+ Y ++I A+DY H + +RD Sbjct: 265 WGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHNQIVYRD 324 Query: 566 LKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAAD 745 LKPENLLLD +G LK+ DFG F+ + T CGTP+Y+APE+++ K Y+ AAD Sbjct: 325 LKPENLLLDRFGHLKIVDFG---FAKRVSTSNCC-TLCGTPDYLAPEIISLKPYN-KAAD 379 Query: 746 VWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 WS GI++F ++AGY PF N M LY+ I V+ P +FS + +L+ +L Sbjct: 380 WWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHLL 432
>Q12152:YP150_YEAST Putative serine/threonine-protein kinase YPL150W - Saccharomyces| cerevisiae (Baker's yeast) Length = 901 Score = 162 bits (409), Expect = 6e-39 Identities = 93/252 (36%), Positives = 140/252 (55%), Gaps = 1/252 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y++ K IGEGSF KV +A +K D+N I RE+ + P Sbjct: 41 YKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKND-------PNIVREVFYHRQFDFPY 93 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 + +L+EV+ ++SK++M LE+ G EL+D +++ ++ E F Q+ AV Y HS Sbjct: 94 ITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHC 153 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLK EN+LLD G K++DFG F+ + L T CGT Y+APE++ + YDG Sbjct: 154 VHRDLKLENILLDKNGNAKLTDFG---FTRECMTKTTLETVCGTTVYMAPELIERRTYDG 210 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPN-LMTLYKLISRANVSCPPWFSTGARNLIKRILDP 910 D+WS G+IL+ L+ GYLPFDD + T +K+++ AR+LI R+L Sbjct: 211 FKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAK 270 Query: 911 NPHTRITIAQIL 946 NP R +++Q+L Sbjct: 271 NPGERPSLSQVL 282
>Q64702:PLK4_MOUSE Serine/threonine-protein kinase PLK4 - Mus musculus (Mouse)| Length = 925 Score = 162 bits (409), Expect = 6e-39 Identities = 85/265 (32%), Positives = 149/265 (56%), Gaps = 3/265 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++G +G+GSFA V A+ G AIK++D+ + + MV++++ E+ ++HP+ Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGK-LGEDEARRYFHQLINAVDYCHSRG 550 V++L+ + +Y+VLE GE+ + N K E EAR + HQ+I + Y HS G Sbjct: 72 VLELYNYFEDNNYVYLVLEMCHNGEMNRYLKNRMKPFSEREARHFMHQIITGMLYLHSHG 131 Query: 551 VYHRDLKPENLLLDSYGALKVSDFGLSA--FSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 + HRDL N+LL +K++DFGL+ P K +T CGTPNY++PE+ A + Sbjct: 132 ILHRDLTLSNILLTRNMNIKIADFGLATQLNMPHEKH----YTLCGTPNYISPEI-ATRS 186 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 G+ +D+WS G + + L+ G PFD + + A+ P + S A++LI ++L Sbjct: 187 AHGLESDIWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPAFLSREAQDLIHQLL 246 Query: 905 DPNPHTRITIAQILEDEWFKKDYKP 979 NP R++++ +L+ + ++ P Sbjct: 247 RRNPADRLSLSSVLDHPFMSRNPSP 271
>P22612:KAPCG_HUMAN cAMP-dependent protein kinase, gamma-catalytic subunit - Homo| sapiens (Human) Length = 351 Score = 162 bits (409), Expect = 6e-39 Identities = 90/261 (34%), Positives = 146/261 (55%), Gaps = 5/261 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E +T+G GSF +V + + G A+K+L++ V++ K VE I E ++ I P Sbjct: 44 FERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPF 103 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+L S +Y+V+E+V GGE+F ++ G+ E A Y Q++ AV Y HS + Sbjct: 104 LVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDL 163 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRDLKPENLL+D G L+V+DFG F+ + K G T CGTP Y+APE++ KGY+ Sbjct: 164 IHRDLKPENLLIDQQGYLQVTDFG---FAKRVK--GRTWTLCGTPEYLAPEIILSKGYN- 217 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPN 913 A D W+ G++++ + G+ PF + +Y+ I V P S+ ++L++ +L + Sbjct: 218 KAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVD 277 Query: 914 -----PHTRITIAQILEDEWF 961 + R + I +WF Sbjct: 278 LTKRFGNLRNGVGDIKNHKWF 298
>P28582:CDPK_DAUCA Calcium-dependent protein kinase - Daucus carota (Carrot)| Length = 532 Score = 162 bits (409), Expect = 6e-39 Identities = 97/266 (36%), Positives = 142/266 (53%), Gaps = 8/266 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMK-LIRHP 370 Y LGK +G G F V + +G A K + + ++ E IKREI ++ L P Sbjct: 81 YTLGKELGRGQFGCVYQCTENSSGQLYACKSILKRKLVSKNDKEDIKREIQILQHLSGQP 140 Query: 371 NVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 N+V+ V + +++V+E GGELFD+I+ G E A Q++N V CH G Sbjct: 141 NIVEFKGVFEDRQSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVVHVCHFMG 200 Query: 551 VYHRDLKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 V HRDLKPEN LL D LK +DFGLS F + K + G+ YVAPEVL + Sbjct: 201 VMHRDLKPENFLLSSKDKDAMLKATDFGLSVFIEEGK---VYRNIVGSAYYVAPEVLR-R 256 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNL 889 Y G D+WS G+IL++L++G PF N ++ I + PW S A++L Sbjct: 257 SY-GKEIDIWSAGVILYILLSGVPPFWAENEKGIFDAILEGVIDFESEPWPSVSNSAKDL 315 Query: 890 IKRILDPNPHTRITIAQILEDEWFKK 967 ++++L +P RIT AQ+L+ W ++ Sbjct: 316 VRKMLTQDPRRRITSAQVLDHPWMRE 341
>P62343:CDPK1_PLAFK Calcium-dependent protein kinase 1 - Plasmodium falciparum (isolate| K1 / Thailand) Length = 524 Score = 162 bits (409), Expect = 6e-39 Identities = 94/273 (34%), Positives = 148/273 (54%), Gaps = 19/273 (6%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLR------------HKMVEQIKREIAT 349 + +G G++ +V + ++ AIKV+ ++ + K+ E+I EI+ Sbjct: 60 RKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNEISL 119 Query: 350 MKLIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAV 529 +K + HPN+++L +V K Y+V EF EGGELF++I+N K E +A Q+++ + Sbjct: 120 LKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGI 179 Query: 530 DYCHSRGVYHRDLKPENLLLDSYGAL---KVSDFGLSAFSPQTKDDGLLHTACGTPNYVA 700 Y H + HRD+KPEN+LL++ +L K+ DFGLS+F + D L GT Y+A Sbjct: 180 CYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSK---DNKLRDRLGTAYYIA 236 Query: 701 PEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRAN--VSCPPW--F 868 PEVL K + DVWSCG+IL++L+ GY PF N + K + + W Sbjct: 237 PEVLRKKYNE--KCDVWSCGVILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNI 294 Query: 869 STGARNLIKRILDPNPHTRITIAQILEDEWFKK 967 S A+ LIK +L + + RIT + L +W KK Sbjct: 295 SEEAKELIKLMLTYDYNKRITAKEALNSKWIKK 327
>P62344:CDPK1_PLAF7 Calcium-dependent protein kinase 1 - Plasmodium falciparum (isolate| 3D7) Length = 524 Score = 162 bits (409), Expect = 6e-39 Identities = 94/273 (34%), Positives = 148/273 (54%), Gaps = 19/273 (6%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLR------------HKMVEQIKREIAT 349 + +G G++ +V + ++ AIKV+ ++ + K+ E+I EI+ Sbjct: 60 RKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNEISL 119 Query: 350 MKLIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAV 529 +K + HPN+++L +V K Y+V EF EGGELF++I+N K E +A Q+++ + Sbjct: 120 LKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGI 179 Query: 530 DYCHSRGVYHRDLKPENLLLDSYGAL---KVSDFGLSAFSPQTKDDGLLHTACGTPNYVA 700 Y H + HRD+KPEN+LL++ +L K+ DFGLS+F + D L GT Y+A Sbjct: 180 CYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSK---DNKLRDRLGTAYYIA 236 Query: 701 PEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRAN--VSCPPW--F 868 PEVL K + DVWSCG+IL++L+ GY PF N + K + + W Sbjct: 237 PEVLRKKYNE--KCDVWSCGVILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNI 294 Query: 869 STGARNLIKRILDPNPHTRITIAQILEDEWFKK 967 S A+ LIK +L + + RIT + L +W KK Sbjct: 295 SEEAKELIKLMLTYDYNKRITAKEALNSKWIKK 327
>Q922R0:PRKX_MOUSE Serine/threonine-protein kinase PRKX - Mus musculus (Mouse)| Length = 355 Score = 161 bits (408), Expect = 8e-39 Identities = 84/232 (36%), Positives = 138/232 (59%) Frame = +2 Query: 209 TIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQLH 388 T+G G+F +V + K+ CA+K++ V+R K + ++ E A +K I HP +++L Sbjct: 51 TVGTGTFGRVNLVKEKTGRQYCALKIMSIPDVIRLKQEQHVQNEKAVLKEINHPFLIKLL 110 Query: 389 EVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRDL 568 +YM++EFV GGELF + N G+ + Y +++ A++Y HS+ + +RDL Sbjct: 111 WTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFYATEIVCAIEYLHSKEIVYRDL 170 Query: 569 KPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAADV 748 KPEN+LLD G +K++DFG F+ + D T CGTP Y+APEV+ KG+ G A D Sbjct: 171 KPENILLDREGHIKLTDFG---FAKKLVD--RTWTLCGTPEYLAPEVIQSKGH-GRAVDW 224 Query: 749 WSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 W+ GI++F +++G+ PF D N +Y+ I + P +++LIK++L Sbjct: 225 WALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPRQLDFTSKDLIKKLL 276
>Q60806:PLK3_MOUSE Serine/threonine-protein kinase PLK3 - Mus musculus (Mouse)| Length = 631 Score = 161 bits (408), Expect = 8e-39 Identities = 97/278 (34%), Positives = 145/278 (52%), Gaps = 2/278 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y G+ +G+G FA+ A DT +G A+KV+ ++ V + E+I EI + ++H + Sbjct: 63 YTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH 122 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+ IY+ LE L L E E R Y Q+++ + Y H RG+ Sbjct: 123 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 182 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAF--SPQTKDDGLLHTACGTPNYVAPEVLADKGY 727 HRDLK N + LKV DFGL+A P+ + T CGTPNYVAPEVL +G+ Sbjct: 183 LHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKK----TICGTPNYVAPEVLLRQGH 238 Query: 728 DGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILD 907 G ADVWS G +++ L+ G PF+ +L Y+ I + + + P S AR L+ IL Sbjct: 239 -GPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILR 297 Query: 908 PNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDV 1021 +P R +I QIL ++F K Y P + V++ D+ Sbjct: 298 ASPRDRPSIEQILRHDFFTKGYTPDRLPVSSCVTVPDL 335
>P08413:KCC2B_RAT Calcium/calmodulin-dependent protein kinase type II beta chain -| Rattus norvegicus (Rat) Length = 542 Score = 161 bits (408), Expect = 8e-39 Identities = 98/262 (37%), Positives = 149/262 (56%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + IG+G+F+ V+ G A K+++ L + ++++RE +L++H N Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKK-LSARDHQKLEREARICRLLKHSN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ AV +CH GV Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKEA 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A+NLI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT + L+ W Sbjct: 250 NQMLTINPAKRITAHEALKHPW 271
>P28652:KCC2B_MOUSE Calcium/calmodulin-dependent protein kinase type II beta chain -| Mus musculus (Mouse) Length = 542 Score = 161 bits (408), Expect = 8e-39 Identities = 98/262 (37%), Positives = 149/262 (56%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + IG+G+F+ V+ G A K+++ L + ++++RE +L++H N Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKK-LSARDHQKLEREARICRLLKHSN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ AV +CH GV Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKEA 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A+NLI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT + L+ W Sbjct: 250 NQMLTINPAKRITAHEALKHPW 271
>Q13554:KCC2B_HUMAN Calcium/calmodulin-dependent protein kinase type II beta chain -| Homo sapiens (Human) Length = 664 Score = 161 bits (408), Expect = 8e-39 Identities = 98/262 (37%), Positives = 149/262 (56%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + IG+G+F+ V+ G A K+++ L + ++++RE +L++H N Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKK-LSARDHQKLEREARICRLLKHSN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ AV +CH GV Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKEA 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A+NLI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT + L+ W Sbjct: 250 NQMLTINPAKRITAHEALKHPW 271
>Q9N3Z3:CHK1_CAEEL Serine/threonine-protein kinase chk-1 - Caenorhabditis elegans| Length = 503 Score = 161 bits (408), Expect = 8e-39 Identities = 125/454 (27%), Positives = 208/454 (45%), Gaps = 28/454 (6%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIR--- 364 Y + +T+GEG+F +V + +T+N A ++ I++E K + Sbjct: 24 YRVVQTLGEGAFGEVLLIVNTKNPEVAAAMKKINIANKSKDFIDNIRKEYLLQKRVSAVG 83 Query: 365 HPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHS 544 H NV+++ + Y+ LE+ +GGELFDKI + A+ YF QLI + + H Sbjct: 84 HDNVIRMIGMRNDPQFYYLFLEYADGGELFDKIEPDCGMSPVFAQFYFKQLICGLKFIHD 143 Query: 545 RGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 V HRD+KPENLLL LK+SDFG++ ++ LL +CGT Y APE+ A K Sbjct: 144 NDVVHRDIKPENLLLTGTHVLKISDFGMATLYRNKGEERLLDLSCGTIPYAAPELCAGKK 203 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPN--LMTLYKLISRANVSCPPWFSTGARNL--I 892 Y G DVWS GI+L ++ G LP+D + + IS ++ PW R L + Sbjct: 204 YRGPPVDVWSSGIVLIAMLTGELPWDRASDASQSYMGWISNTSLDERPWKKIDVRALCML 263 Query: 893 KRILDPNPHTRITIAQILEDEWFKKDY--------KPPLSEHNEDVSLEDVDAAFDSSEE 1048 ++I+ R TI QI D W++ ++ +P N D ++ A S++ Sbjct: 264 RKIVTDKTDKRATIEQIQADPWYQHNFGQVETPNGRPLKRARNNDENITCTQQAECSAKR 323 Query: 1049 HLVAERREK---PESMNA-FALISRSAGFNLGNLFEKE------MMGMVKRETSFASQRT 1198 + EK E NA F+ +++ L + + MV R T F Sbjct: 324 RHLETPNEKSTLAERQNASFSQPTKTEDLLLTQHIDMSQTNSNLLQRMVCRMTRFCVVTD 383 Query: 1199 PQEIMSKIEEACGPLGFNVRK-QNYKMKLKGDKTGRKGHLSVATEVFEVAPSLH--MVEL 1369 + K+ A GF VR+ +Y++ + T R+ + V+ P MV+ Sbjct: 384 IRSTYQKVARASEHAGFGVRETDDYRLLV----TWREVSMMVSLYTMGDIPDKPRVMVDF 439 Query: 1370 RKTGGDTLEFHSFYQNFSSELKDIVWKTESNTIA 1471 R++ GD ++F + + + + + + +N +A Sbjct: 440 RRSRGDGIQFKKMFMDVRNRMHEWICTDGNNWLA 473
>Q8IBS5:CDPK4_PLAF7 Calcium-dependent protein kinase 4 - Plasmodium falciparum (isolate| 3D7) Length = 528 Score = 161 bits (408), Expect = 8e-39 Identities = 112/396 (28%), Positives = 195/396 (49%), Gaps = 11/396 (2%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 K +G+GSF +V +++D G AIKV+ + HV R E + RE+ +K++ H N+++L Sbjct: 74 KILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDHINIMKL 133 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 +E + Y+V + GGELFD+I++ + E +A R Q+++ + Y H V HRD Sbjct: 134 YEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITYMHKNNVVHRD 193 Query: 566 LKPENLLLDSYG----ALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 LKPEN+LL++ +K+ DFGLS +K + GT Y+AP+VL G Sbjct: 194 LKPENILLETKNKEDMIIKIIDFGLSTHFEYSKK---MKDKIGTAYYIAPDVL--HGTYD 248 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP-PWF---STGARNLIKRI 901 D+WSCG+IL++L++G PF+ N + K + + P F S A++LIK++ Sbjct: 249 EKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVEAGKYTFDLPQFKKISDKAKDLIKKM 308 Query: 902 LDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERREKPE 1081 L RI+ LE EW K S+ N ++ + ++ + + + ++ Sbjct: 309 LMYTSAVRISARDALEHEWIKM----MTSKDNLNIDIPSLELSIANIRQFQSTQK----- 359 Query: 1082 SMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEE-ACGPLGFNVR 1258 L + ++ M + T+ + +I K+++ G L N Sbjct: 360 ------------------LAQAALLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNEL 401 Query: 1259 KQNYK--MKLKGDKTGRKGHLSVATEVFEVAPSLHM 1360 YK +KLKG+ T + ++ EV ++ S+ + Sbjct: 402 IIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSIDL 437
>Q9D411:TSSK4_MOUSE Testis-specific serine/threonine-protein kinase 4 - Mus musculus| (Mouse) Length = 328 Score = 160 bits (406), Expect = 1e-38 Identities = 98/301 (32%), Positives = 154/301 (51%), Gaps = 15/301 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 YE+GK IG GS+ V A T+ A+K++ + + + + REI MK++RH Sbjct: 25 YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKY 84 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ ++ + + S++Y++LE +GG++ + I G E A ++F Q+ + Y HS+G+ Sbjct: 85 LINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFSQMALGIAYLHSKGI 144 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKD-------------DGLLHTACGTPNY 694 HRDLK ENLLLD +K+SDFG + P ++ L T CG+ Y Sbjct: 145 VHRDLKLENLLLDKRENVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAY 204 Query: 695 VAPEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPP--WF 868 PE+L Y+ +D WS G+IL+ L+ LPFDD NL L + ++ V+ P Sbjct: 205 ACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLR-ETQKEVTFPANLTI 263 Query: 869 STGARNLIKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEE 1048 S +NLI ++L + R TI +L D W K P NE LE + S++ Sbjct: 264 SQECKNLILQLLRQST-KRATILDVLRDPWMLK--FQPEQPSNEIRLLEAMYQPTSSAKR 320 Query: 1049 H 1051 H Sbjct: 321 H 321
>Q9H4B4:PLK3_HUMAN Serine/threonine-protein kinase PLK3 - Homo sapiens (Human)| Length = 646 Score = 160 bits (406), Expect = 1e-38 Identities = 97/278 (34%), Positives = 145/278 (52%), Gaps = 2/278 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y G+ +G+G FA+ A DT G+ A+KV+ ++ V + E+I EI + ++H + Sbjct: 62 YLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRH 121 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+ IY+ LE L L E E R Y Q+++ + Y H RG+ Sbjct: 122 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 181 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAF--SPQTKDDGLLHTACGTPNYVAPEVLADKGY 727 HRDLK N + LKV DFGL+A P+ + T CGTPNYVAPEVL +G+ Sbjct: 182 LHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKK----TICGTPNYVAPEVLLRQGH 237 Query: 728 DGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILD 907 G ADVWS G +++ L+ G PF+ +L Y+ I + + + P S AR L+ IL Sbjct: 238 -GPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILR 296 Query: 908 PNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDV 1021 +P R +I QIL ++F K Y P + V++ D+ Sbjct: 297 ASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVPDL 334
>Q923T9:KCC2G_MOUSE Calcium/calmodulin-dependent protein kinase type II gamma chain - Mus| musculus (Mouse) Length = 529 Score = 160 bits (406), Expect = 1e-38 Identities = 111/346 (32%), Positives = 180/346 (52%), Gaps = 9/346 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ + A K+++ L + ++++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A HQ++ +V++ H + Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDI 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q + A GTP Y++PEVL Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGL-AIEVQGEQQAWFGFA-GTPGYLSPEVLRKDP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A+NLI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 893 KRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDV--SLEDVDAAFDSSEEHLVAER 1066 ++L NP RIT Q L+ W + H ++ L +A R Sbjct: 250 NQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNA------------R 297 Query: 1067 REKPESMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQ 1204 R+ ++ L+SR+ L +K G+ KR++S + PQ Sbjct: 298 RKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKKRKSSSSVHLMPQ 343
>Q13555:KCC2G_HUMAN Calcium/calmodulin-dependent protein kinase type II gamma chain -| Homo sapiens (Human) Length = 558 Score = 160 bits (406), Expect = 1e-38 Identities = 111/346 (32%), Positives = 180/346 (52%), Gaps = 9/346 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ + A K+++ L + ++++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A HQ++ +V++ H + Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDI 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q + A GTP Y++PEVL Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGL-AIEVQGEQQAWFGFA-GTPGYLSPEVLRKDP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A+NLI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 893 KRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDV--SLEDVDAAFDSSEEHLVAER 1066 ++L NP RIT Q L+ W + H ++ L +A R Sbjct: 250 NQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNA------------R 297 Query: 1067 REKPESMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQ 1204 R+ ++ L+SR+ L +K G+ KR++S + PQ Sbjct: 298 RKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKKRKSSSSVHLMPQ 343
>Q6DGS3:KCC2D_DANRE Calcium/calmodulin-dependent protein kinase type II delta chain -| Danio rerio (Zebrafish) (Brachydanio rerio) Length = 493 Score = 160 bits (406), Expect = 1e-38 Identities = 95/262 (36%), Positives = 150/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ +G A K+++ L + ++++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCVKISSGQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 71 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ +V +CH G+ Sbjct: 72 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHVNGI 131 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL Sbjct: 132 VHRDLKPENLLLASKMKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKDP 189 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 190 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT A+ + W Sbjct: 249 NKMLTINPSKRITAAEAPKHPW 270
>P53683:CDPK2_ORYSJ Calcium-dependent protein kinase, isoform 2 - Oryza sativa subsp.| japonica (Rice) Length = 533 Score = 160 bits (406), Expect = 1e-38 Identities = 111/382 (29%), Positives = 181/382 (47%), Gaps = 8/382 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMK-LIRHP 370 Y LGK +G G F + + +G A K + + ++ E I+REI M+ L Sbjct: 85 YSLGKELGRGQFGVTYLCTEIASGKQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQQ 144 Query: 371 NVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 N+V+ KS +++V+E GGELFD+I+ G E A ++N V+ CH G Sbjct: 145 NIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYSERAAATICRAVVNVVNICHFMG 204 Query: 551 VYHRDLKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 V HRDLKPEN LL + LK +DFGLS F + K + G+ YVAPEVL + Sbjct: 205 VMHRDLKPENFLLATKEENAMLKATDFGLSVFIEEGK---MYRDIVGSAYYVAPEVLR-R 260 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANV--SCPPW--FSTGARNL 889 Y G DVWS G+IL++L++G PF ++ I + + PW S A++L Sbjct: 261 NY-GKEIDVWSAGVILYILLSGVPPFWAETEKGIFDAILQGEIDFESQPWPSISESAKDL 319 Query: 890 IKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERR 1069 ++++L +P RIT AQ+L+ W + + + S + +D+A S + A + Sbjct: 320 VRKMLTQDPKKRITSAQVLQHPWLR----------DGEASDKPIDSAVLSRMKQFRAMNK 369 Query: 1070 EKPESMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEEACGPLGF 1249 K ++ A NL E+E+ G+ + T+ + + +++ LG Sbjct: 370 LKKMALKVIA----------SNLNEEEIKGLKQMFTNMDTDNSGTITYEELKAGLAKLGS 419 Query: 1250 NVRKQNYKMKLKGDKTGRKGHL 1315 + + K ++ G + Sbjct: 420 KLSEAEVKQLMEAADVDGNGSI 441
>Q7RAH3:CDPK1_PLAYO Calcium-dependent protein kinase 1 - Plasmodium yoelii yoelii| Length = 535 Score = 160 bits (406), Expect = 1e-38 Identities = 93/271 (34%), Positives = 146/271 (53%), Gaps = 17/271 (6%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLR----------HKMVEQIKREIATMK 355 + +G G++ +V + K+ + AIKV+ ++ + K E+I EI+ +K Sbjct: 61 RKLGSGAYGEVLLCKEKNGHSEKAIKVIKKSQFDKGRYNDDNKNIEKFHEEIYNEISLLK 120 Query: 356 LIRHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDY 535 + HPN+++L +V K Y+V EF EGGELF++I+N K E +A Q+++ + Y Sbjct: 121 SLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICY 180 Query: 536 CHSRGVYHRDLKPENLLLDSYGAL---KVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPE 706 H + HRD+KPEN+LL++ +L K+ DFGLS+F + D L GT Y+APE Sbjct: 181 LHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSK---DYKLRDRLGTAYYIAPE 237 Query: 707 VLADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRAN--VSCPPW--FST 874 VL K + DVWSCG+I+++L+ GY PF N + K + + W S Sbjct: 238 VLKKKYNE--KCDVWSCGVIMYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISD 295 Query: 875 GARNLIKRILDPNPHTRITIAQILEDEWFKK 967 A+ LIK +L + + R T + L W KK Sbjct: 296 EAKELIKLMLTYDYNKRCTAEEALNSRWIKK 326
>P22216:RAD53_YEAST Serine/threonine-protein kinase RAD53 - Saccharomyces cerevisiae| (Baker's yeast) Length = 821 Score = 160 bits (405), Expect = 2e-38 Identities = 91/273 (33%), Positives = 143/273 (52%), Gaps = 18/273 (6%) Frame = +2 Query: 200 LGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVV 379 + + +G+G+FA VK A + G T A+K++ + V+ + ++ + RE+ ++ + HP +V Sbjct: 200 IDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGN--MDGVTRELEVLQKLNHPRIV 257 Query: 380 QLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYH 559 +L YMV+EFV GG+L D + G +GED R Q++ A+ Y HS G+ H Sbjct: 258 RLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISH 317 Query: 560 RDLKPENLLL--DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYD- 730 RDLKP+N+L+ D +K++DFGL+ + + T CGT YVAPEV+ K Sbjct: 318 RDLKPDNILIEQDDPVLVKITDFGLAKVQ---GNGSFMKTFCGTLAYVAPEVIRGKDTSV 374 Query: 731 -----------GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPW---- 865 D+WS G +++V++ G+LPF LYK I R + P Sbjct: 375 SPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFR 434 Query: 866 FSTGARNLIKRILDPNPHTRITIAQILEDEWFK 964 S AR+ I +L +P+ R T A+ L W K Sbjct: 435 ISEEARDFIDSLLQVDPNNRSTAAKALNHPWIK 467
>Q39030:KPK19_ARATH Serine/threonine-protein kinase AtPK19 - Arabidopsis thaliana| (Mouse-ear cress) Length = 471 Score = 160 bits (405), Expect = 2e-38 Identities = 89/263 (33%), Positives = 148/263 (56%), Gaps = 6/263 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+ K +G+G+F KV + A+KV+ ++ ++ E +K E + I HP Sbjct: 140 FEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPF 199 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +VQL +K ++Y+VL+F+ GG LF ++ + G ED AR Y ++++AV + H +G+ Sbjct: 200 IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 259 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLS-AFSPQTKDDGLLHTACGTPNYVAPEVLADKGYD 730 HRDLKPEN+L+D G + ++DFGL+ F T+ + + CGT Y+APE++ KG+D Sbjct: 260 MHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSM----CGTTEYMAPEIVRGKGHD 315 Query: 731 GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDP 910 AAD WS GI+L+ ++ G PF K++ + + P + S A L+K +L Sbjct: 316 -KAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIV-KDKIKLPQFLSNEAHALLKGLLQK 373 Query: 911 NPHTRI-----TIAQILEDEWFK 964 P R+ +I + +WFK Sbjct: 374 EPERRLGSGPSGAEEIKKHKWFK 396
>Q9VKN7:AURKB_DROME Serine/threonine-protein kinase Ial - Drosophila melanogaster| (Fruit fly) Length = 329 Score = 160 bits (405), Expect = 2e-38 Identities = 88/259 (33%), Positives = 140/259 (54%), Gaps = 2/259 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +E+G +G G F +V +A++ + A+KV+ + + + + Q+ REI ++HP+ Sbjct: 53 FEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHPH 112 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEAR--RYFHQLINAVDYCHSR 547 +++L +S+IY+ LE GELF + + DE R +Y +Q+ NA++YCH Sbjct: 113 ILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLN 172 Query: 548 GVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGY 727 V HRDLKPEN+LL S LK++DFG SA +P K T CGT +Y+ PE++ Y Sbjct: 173 NVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNK----RRTLCGTLDYLPPEMVDGNSY 228 Query: 728 DGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILD 907 D + D W GI+ + + G PF+ + + Y I R +S P S G + LI +L Sbjct: 229 DD-SVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCKELIGGLLR 287 Query: 908 PNPHTRITIAQILEDEWFK 964 RIT+ ++ W K Sbjct: 288 KESKGRITLVDVMTHYWVK 306
>P11730:KCC2G_RAT Calcium/calmodulin-dependent protein kinase type II gamma chain -| Rattus norvegicus (Rat) Length = 527 Score = 160 bits (404), Expect = 2e-38 Identities = 95/262 (36%), Positives = 150/262 (57%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ + A K+++ L + ++++RE +L++HPN Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKK-LSARDHQKLEREARICRLLKHPN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A HQ++ +V++ H + Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDI 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q + A GTP Y++PEVL Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGL-AIEVQGEQQAWFGFA-GTPGYLSPEVLRKDP 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A+NLI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RIT Q L+ W Sbjct: 250 NQMLTINPAKRITADQALKHPW 271
>Q9R011:PLK3_RAT Serine/threonine-protein kinase PLK3 - Rattus norvegicus (Rat)| Length = 615 Score = 159 bits (403), Expect = 3e-38 Identities = 113/364 (31%), Positives = 170/364 (46%), Gaps = 13/364 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y G+ +G+G FA+ A DT A+KV+ ++ V + E+I EI + ++H + Sbjct: 31 YIKGRLLGKGGFARCYEATDTETSIAYAVKVIPQSRVAKPHQREKIINEIELHRDLQHRH 90 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+ IY+ LE L L E E R Y Q+++ + Y H RG+ Sbjct: 91 IVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 150 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAF--SPQTKDDGLLHTACGTPNYVAPEVLADKGY 727 HRDLK N + LKV DFGL+A P+ + T CGTPNYVAPEVL +G+ Sbjct: 151 LHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKK----TICGTPNYVAPEVLLRQGH 206 Query: 728 DGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILD 907 G ADVWS G +++ L+ G PF+ +L Y+ I + + + P S AR L+ IL Sbjct: 207 -GPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILR 265 Query: 908 PNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVD------AAFDSSEEHLVAERR 1069 +P R +I QIL ++F K Y P + V++ D+ + F + L R+ Sbjct: 266 ASPRDRPSIEQILRHDFFTKGYTPDRLPVSSCVTVPDLTPPNPARSLFAKVTKSLFGRRK 325 Query: 1070 EK-----PESMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEEAC 1234 K E N L+S ++G+ V+ E AS P ++ E Sbjct: 326 SKNKNHSEEQDNVSCLVSGLMRTSIGH-------PDVRPEAPAASALAPVSLVETAAEDS 378 Query: 1235 GPLG 1246 P G Sbjct: 379 SPRG 382
>Q21734:KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-1 - Caenorhabditis| elegans Length = 784 Score = 159 bits (403), Expect = 3e-38 Identities = 87/248 (35%), Positives = 148/248 (59%), Gaps = 3/248 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTR---NGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIR 364 +EL K +G+GSF KV + + R +G A+KVL + L+ + ++ K E + I Sbjct: 104 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL-KKATLKVRDRQRTKLERNILAHIS 162 Query: 365 HPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHS 544 HP +V+LH ++ K+Y++L+F+ GG+LF ++ ED+ + Y +L A+++ HS Sbjct: 163 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 222 Query: 545 RGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 G+ +RDLKPEN+LLD+ G +KV+DFGLS + ++ CGT Y+APEV+ +G Sbjct: 223 LGIVYRDLKPENILLDADGHIKVTDFGLS--KEAIDSEKKTYSFCGTVEYMAPEVINRRG 280 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRIL 904 + MAAD WS G+++F ++ G+LPF + I +A +S P + + A++L++ + Sbjct: 281 H-SMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALF 339 Query: 905 DPNPHTRI 928 N R+ Sbjct: 340 KRNSQNRL 347 Score = 140 bits (352), Expect = 2e-32 Identities = 102/328 (31%), Positives = 170/328 (51%), Gaps = 22/328 (6%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLR--HKMVEQIKREIATMKLIRH 367 YE+ + IG G+ + V C +K R + ++ K V E+ L+RH Sbjct: 454 YEILEKIGNGAHSVVH---------KCQMKATRRKYAVKIVKKAVFDATEEVDI--LLRH 502 Query: 368 PN---VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLG-EDEARRYFHQLINAVDY 535 + VV+L +V ++ IYM+ E EGGEL DK+VN LG E E L+NAV Y Sbjct: 503 SHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQY 562 Query: 536 CHSRGVYHRDLKPENLLL----DSYGALKVSDFGLSAFSPQTK-DDGLLHTACGTPNYVA 700 HS+ V HRDL N+L +L++ DFG F+ Q++ ++G+L T C T +VA Sbjct: 563 LHSQQVAHRDLTAANILFALKDGDPSSLRIVDFG---FAKQSRAENGMLMTPCYTAQFVA 619 Query: 701 PEVLADKGYDGMAADVWSCGIILFVLMAGYLPF-----DDPNLMTLYKLISRANVSCPPW 865 PEVL +GYD + DVWS G++L ++ G PF D P+ + + +++ P W Sbjct: 620 PEVLRKQGYD-RSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVW 678 Query: 866 --FSTGARNLIKRILDPNPHTRITIAQILEDEWFKKDY----KPPLSEHNEDVSLEDVDA 1027 S A++L++++LD +P+ R+T Q L+ +W + +P SE ++ +++V Sbjct: 679 DTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKV 738 Query: 1028 AFDSSEEHLVAERREKPESMNAFALISR 1111 A + + + + + + + + AL R Sbjct: 739 ALEQTYKAIASAPSVQLRPVGSSALAKR 766
>Q80YE7:DAPK1_MOUSE Death-associated protein kinase 1 - Mus musculus (Mouse)| Length = 1442 Score = 159 bits (403), Expect = 3e-38 Identities = 102/291 (35%), Positives = 155/291 (53%), Gaps = 17/291 (5%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVL---RHKMVEQIKREIATMKLIR 364 Y+ G+ +G G FA VK ++ G A K + + R E I+RE++ +K IR Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIR 72 Query: 365 HPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHS 544 HPNV+ LHEV +K+ + ++LE V GGELFD + L E+EA + Q+++ V Y HS Sbjct: 73 HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILSGVYYLHS 132 Query: 545 RGVYHRDLKPENLLLDSYGA----LKVSDFGLS---AFSPQTKDDGLLHTACGTPNYVAP 703 + H DLKPEN++L +K+ DFGL+ F + K+ GTP +VAP Sbjct: 133 LQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKN------IFGTPEFVAP 186 Query: 704 EVLADKGYD--GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWF--- 868 E++ Y+ G+ AD+WS G+I ++L++G PF +S N F Sbjct: 187 EIV---NYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYDFEEEFFRN 243 Query: 869 -STGARNLIKRILDPNPHTRITIAQILEDEWFK-KDYKPPLSEHNEDVSLE 1015 ST A++ I+R+L +P R+TI L+ W K KD + LS V++E Sbjct: 244 TSTLAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNME 294
>Q9M077:AUR1_ARATH Serine/threonine-protein kinase Aurora-1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 294 Score = 159 bits (403), Expect = 3e-38 Identities = 81/264 (30%), Positives = 146/264 (55%), Gaps = 2/264 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++GK +G G F V +A++ R+ A+KVL ++ + + ++ Q++RE+ +RHPN Sbjct: 31 FDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQLQQSQVEHQLRREVEIQSHLRHPN 90 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ + ++Y++LE+ GEL+ + E A Y L A+ YCH + V Sbjct: 91 ILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATYVASLARALIYCHGKHV 150 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLL+ + G LK++DFG S + + T CGT +Y+ PE++ +D Sbjct: 151 IHRDIKPENLLIGAQGELKIADFGWSVHTFNRR-----RTMCGTLDYLPPEMVESVEHDA 205 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP--PWFSTGARNLIKRILD 907 + D+WS GI+ + + G PF+ Y+ I + ++ P P S A++LI ++L Sbjct: 206 -SVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISASAKDLISQMLV 264 Query: 908 PNPHTRITIAQILEDEWFKKDYKP 979 R+ + ++LE W ++ P Sbjct: 265 KESSQRLPLHKLLEHPWIVQNADP 288
>Q96PF2:TSSK2_HUMAN Testis-specific serine/threonine-protein kinase 2 - Homo sapiens| (Human) Length = 358 Score = 159 bits (402), Expect = 4e-38 Identities = 89/262 (33%), Positives = 144/262 (54%), Gaps = 5/262 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y +G +G+GS+AKVK A R A+K++DR + + RE+ + + H + Sbjct: 12 YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGS 71 Query: 374 VVQLHEVM-ASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 +++ +E+ S +IY+++E G+L + I G L ED AR+ F QL +AV YCH Sbjct: 72 IIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLD 131 Query: 551 VYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLL--HTACGTPNYVAPEVLADKG 724 + HRDLK ENLLLD +K+SDFG S + + ++ T CG+ Y APEVL Sbjct: 132 IVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIP 191 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP--PWFSTGARNLIKR 898 Y D+WS G+IL++++ G +P+DD ++ + ++ V P + ++LI R Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYR 251 Query: 899 ILDPNPHTRITIAQILEDEWFK 964 +L P+ R+ I +IL W + Sbjct: 252 MLQPDVSQRLHIDEILSHSWLQ 273
>P18653:KS6A1_MOUSE Ribosomal protein S6 kinase alpha-1 - Mus musculus (Mouse)| Length = 724 Score = 159 bits (402), Expect = 4e-38 Identities = 101/286 (35%), Positives = 159/286 (55%), Gaps = 13/286 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y + +TIG GS++ K A+KV+D++ + E+I+ ++ +HPN Sbjct: 407 YVVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKS---KRDPSEEIE---ILLRYGQHPN 460 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ L +V +Y+V E + GGEL DKI+ E EA H + V+Y HS+GV Sbjct: 461 IITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTISKTVEYLHSQGV 520 Query: 554 YHRDLKPENLL-LDSYG---ALKVSDFGLSAFSPQTK-DDGLLHTACGTPNYVAPEVLAD 718 HRDLKP N+L +D G L++ DFG F+ Q + ++GLL T C T N+VAPEVL Sbjct: 521 VHRDLKPSNILYVDESGNPECLRICDFG---FAKQLRAENGLLMTPCYTANFVAPEVLKR 577 Query: 719 KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA-----NVSCPPW--FSTG 877 +GYD D+WS GI+L+ ++AGY PF + T ++++R +S W S Sbjct: 578 QGYD-EGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSET 636 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWF-KKDYKPPLSEHNEDVSL 1012 A++L+ ++L +PH R+T Q+L+ W +KD P ++D+ L Sbjct: 637 AKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQSQLSHQDLQL 682 Score = 137 bits (345), Expect = 2e-31 Identities = 87/249 (34%), Positives = 146/249 (58%), Gaps = 4/249 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKV-KVAKDTR--NGATCAIKVLDRNHV-LRHKMVEQIKREIATMKLI 361 +EL K +G+GSF KV V K TR +G A+KVL + + +R ++ +++R+I + + Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDI--LADV 119 Query: 362 RHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCH 541 HP VV+LH ++ K+Y++L+F+ GG+LF ++ E++ + Y +L +D+ H Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179 Query: 542 SRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 S G+ +RDLKPEN+LLD G +K++DFGLS + ++ CGT Y+APEV+ + Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQ 237 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRI 901 G+ +AD WS G++ + D MT LI +A + P + ST A++L++ + Sbjct: 238 GHT-HSADWWSYGVL--------MGKDRKETMT---LILKAKLGMPQFLSTEAQSLLRAL 285 Query: 902 LDPNPHTRI 928 NP R+ Sbjct: 286 FKRNPANRL 294
>Q15418:KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 - Homo sapiens (Human)| Length = 735 Score = 159 bits (402), Expect = 4e-38 Identities = 101/286 (35%), Positives = 160/286 (55%), Gaps = 13/286 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y + +TIG GS+++ K A+KV+D++ + E+I+ ++ +HPN Sbjct: 418 YVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKS---KRDPSEEIE---ILLRYGQHPN 471 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 ++ L +V +Y+V E + GGEL DKI+ E EA H + V+Y HS+GV Sbjct: 472 IITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGV 531 Query: 554 YHRDLKPENLL-LDSYG---ALKVSDFGLSAFSPQTK-DDGLLHTACGTPNYVAPEVLAD 718 HRDLKP N+L +D G L++ DFG F+ Q + ++GLL T C T N+VAPEVL Sbjct: 532 VHRDLKPSNILYVDESGNPECLRICDFG---FAKQLRAENGLLMTPCYTANFVAPEVLKR 588 Query: 719 KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA-----NVSCPPW--FSTG 877 +GYD D+WS GI+L+ ++AGY PF + T ++++R +S W S Sbjct: 589 QGYD-EGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSET 647 Query: 878 ARNLIKRILDPNPHTRITIAQILEDEWF-KKDYKPPLSEHNEDVSL 1012 A++L+ ++L +PH R+T Q+L+ W +KD P ++D+ L Sbjct: 648 AKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQL 693 Score = 155 bits (393), Expect = 4e-37 Identities = 89/249 (35%), Positives = 151/249 (60%), Gaps = 4/249 (1%) Frame = +2 Query: 194 YELGKTIGEGSFAKV-KVAKDTR--NGATCAIKVLDRNHV-LRHKMVEQIKREIATMKLI 361 +EL K +G+GSF KV V K TR +G A+KVL + + +R ++ +++R+I + + Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDI--LADV 119 Query: 362 RHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCH 541 HP VV+LH ++ K+Y++L+F+ GG+LF ++ E++ + Y +L +D+ H Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179 Query: 542 SRGVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 S G+ +RDLKPEN+LLD G +K++DFGLS + ++ CGT Y+APEV+ + Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQ 237 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRI 901 G+ +AD WS G+++F ++ G LPF + LI +A + P + ST A++L++ + Sbjct: 238 GH-SHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRAL 296 Query: 902 LDPNPHTRI 928 NP R+ Sbjct: 297 FKRNPANRL 305
>Q3MHJ9:KCC2B_BOVIN Calcium/calmodulin-dependent protein kinase type II beta chain -| Bos taurus (Bovine) Length = 542 Score = 159 bits (402), Expect = 4e-38 Identities = 97/262 (37%), Positives = 148/262 (56%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + IG+G+F+ V+ G A K+++ L + ++++RE +L++H N Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKK-LSARDHQKLEREARICRLLKHSN 72 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ AV +CH GV Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL + Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKEA 190 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A+NLI Sbjct: 191 Y-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI 249 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RI + L+ W Sbjct: 250 NQMLTINPAKRIMAHEALKHPW 271
>P39009:DUN1_YEAST DNA damage response protein kinase DUN1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 513 Score = 159 bits (402), Expect = 4e-38 Identities = 99/285 (34%), Positives = 148/285 (51%), Gaps = 29/285 (10%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y LGK +G G +A VK AK+ + G A+K+ K +Q + E + ++HPN Sbjct: 200 YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPN 259 Query: 374 VVQLHEVMA---SKSKI--YMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYC 538 +V L + SKS+I Y+VLE ++ GELF++IV L +DE++ F QL+ + Y Sbjct: 260 IVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYL 319 Query: 539 HSRGVYHRDLKPENLLLDSYG-------------------ALKVSDFGLSAFSPQTKDDG 661 H + + HRD+KPEN+LL+ +K++DFGL+ F+ + + Sbjct: 320 HEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQ--- 376 Query: 662 LLHTACGTPNYVAPEVLADKGYDGMAADVWSCGIILFVLMAGYLPFDD---PNLMTLYKL 832 +T CGTP+YVAPEVL KGY D+WS G+IL+V + G+ PF D P + L Sbjct: 377 FTNTLCGTPSYVAPEVLTKKGYTS-KVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQIL 435 Query: 833 ISRANVSCPPW--FSTGARNLIKRILDPNPHTRITIAQILEDEWF 961 ++ P W +LI +L NP R I + L WF Sbjct: 436 QAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWF 480
>P38147:CHK1_YEAST Serine/threonine-protein kinase CHK1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 527 Score = 159 bits (402), Expect = 4e-38 Identities = 101/269 (37%), Positives = 160/269 (59%), Gaps = 16/269 (5%) Frame = +2 Query: 200 LGKTIGEGSFAKVKVAKDTRNGATC-AIKVLDRNHVLRHKMV----EQIKREIATM-KLI 361 LG T+G+G+FA VK A + + A+K + HV K + + I +E+ K Sbjct: 17 LGDTVGQGAFACVKNAHLQMDPSIILAVKFI---HVPTCKKMGLSDKDITKEVVLQSKCS 73 Query: 362 RHPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCH 541 +HPNV++L + SK ++++LE +GG+LFDKI + D A+ YF QL++A++Y H Sbjct: 74 KHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLH 133 Query: 542 SR-GVYHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTAC---GTPNYVAPEV 709 GV HRD+KPEN+LLD G LK++DFGL+ S + DG L + G+P Y+APEV Sbjct: 134 VECGVAHRDIKPENILLDKNGNLKLADFGLA--SQFRRKDGTLRVSMDQRGSPPYMAPEV 191 Query: 710 L-ADKGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMT---LYKLISRANVSCPPW--FS 871 L +++GY D+WS GI+LFVL+ G P++ P+L ++ + + N++ PW Sbjct: 192 LYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIE 251 Query: 872 TGARNLIKRILDPNPHTRITIAQILEDEW 958 NL+++IL P+P+ R+T+ + W Sbjct: 252 FTHLNLLRKILQPDPNKRVTLKALKLHPW 280
>Q683C9:AUR2_ARATH Serine/threonine-protein kinase Aurora-2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 282 Score = 159 bits (402), Expect = 4e-38 Identities = 82/264 (31%), Positives = 147/264 (55%), Gaps = 2/264 (0%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 +++GK +G G F V +A++ R+ A+KVL + + + ++ Q++RE+ +RHPN Sbjct: 19 FDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQSQVEHQLRREVEIQSHLRHPN 78 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +++L+ + ++Y++LE+ GEL+ ++ E A Y L A+ YCH + V Sbjct: 79 ILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVASLARALIYCHGKHV 138 Query: 554 YHRDLKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDG 733 HRD+KPENLL+ + G LK++DFG S + + T CGT +Y+ PE++ +D Sbjct: 139 IHRDIKPENLLIGAQGELKIADFGWSVHTFNRR-----RTMCGTLDYLPPEMVESVEHDA 193 Query: 734 MAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCP--PWFSTGARNLIKRILD 907 + D+WS GI+ + + G PF+ YK I + ++ P P S+ A++LI ++L Sbjct: 194 -SVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSSSAKDLISQMLV 252 Query: 908 PNPHTRITIAQILEDEWFKKDYKP 979 R+ + ++LE W ++ P Sbjct: 253 KESTQRLALHKLLEHPWIVQNADP 276
>Q06850:CDPK1_ARATH Calcium-dependent protein kinase, isoform AK1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 610 Score = 159 bits (401), Expect = 5e-38 Identities = 112/364 (30%), Positives = 180/364 (49%), Gaps = 8/364 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMK-LIRHP 370 Y LG+ +G+G F + + G A K + + +L + VE ++REI M L HP Sbjct: 150 YSLGRKLGQGQFGTTFLCVEKTTGKEFACKSIAKRKLLTDEDVEDVRREIQIMHHLAGHP 209 Query: 371 NVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRG 550 NV+ + +++V+E GGELFD+I+ G E +A ++ V+ CHS G Sbjct: 210 NVISIKGAYEDVVAVHLVMECCAGGELFDRIIQRGHYTERKAAELTRTIVGVVEACHSLG 269 Query: 551 VYHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADK 721 V HRDLKPEN L S LK DFGLS F K D + G+P YVAPEVL K Sbjct: 270 VMHRDLKPENFLFVSKHEDSLLKTIDFGLSMF---FKPDDVFTDVVGSPYYVAPEVLR-K 325 Query: 722 GYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANV--SCPPW--FSTGARNL 889 Y G ADVWS G+I+++L++G PF +++ + ++ S PW S A++L Sbjct: 326 RY-GPEADVWSAGVIVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAKDL 384 Query: 890 IKRILDPNPHTRITIAQILEDEWFKKDYKPPLSEHNEDVSLEDVDAAFDSSEEHLVAERR 1069 ++++L +P R+T Q+L W + D P D DS+ V R Sbjct: 385 VRKMLVRDPKKRLTAHQVLCHPWVQVDGVAP-------------DKPLDSA----VLSRM 427 Query: 1070 EKPESMNAFALISRSAGFNLGNLFEKEMMGMVKRETSFASQRTPQEIMSKIEEACGPLGF 1249 ++ +MN F ++ +L E+E+ G+ + + ++ Q +++ +G Sbjct: 428 KQFSAMNKFKKMALRV--IAESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGA 485 Query: 1250 NVRK 1261 N+++ Sbjct: 486 NLKE 489
>Q9DG02:KCC2D_XENLA Calcium/calmodulin-dependent protein kinase type II delta chain -| Xenopus laevis (African clawed frog) Length = 475 Score = 158 bits (400), Expect = 7e-38 Identities = 94/262 (35%), Positives = 148/262 (56%), Gaps = 7/262 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPN 373 Y+L + +G+G+F+ V+ G A K+++ L + ++++RE +L++HPN Sbjct: 13 YQLFEELGKGAFSVVRRCIKINIGQEYAAKIINTKK-LSARDHQKLEREAKICRLLKHPN 71 Query: 374 VVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGV 553 +V+LH+ ++ + Y+V + V GGELF+ IV E +A Q++ +V++CH G+ Sbjct: 72 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 131 Query: 554 YHRDLKPENLLLDSY---GALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKG 724 HRDLKPENLLL S A+K++DFGL A Q A GTP Y++PEVL Sbjct: 132 VHRDLKPENLLLASKLKGAAVKLADFGL-AIEVQGDQQAWFGFA-GTPGYLSPEVLRKDP 189 Query: 725 YDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRA--NVSCPPW--FSTGARNLI 892 Y G D+W+CG+IL++L+ GY PF D + LY+ I + P W + A++LI Sbjct: 190 Y-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248 Query: 893 KRILDPNPHTRITIAQILEDEW 958 ++L NP RI + L W Sbjct: 249 NKMLTINPAKRINATEALRHPW 270
>Q9WTK7:STK11_MOUSE Serine/threonine-protein kinase 11 - Mus musculus (Mouse)| Length = 436 Score = 158 bits (399), Expect = 9e-38 Identities = 95/273 (34%), Positives = 154/273 (56%), Gaps = 7/273 (2%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVE-QIKREIATMKLIRHP 370 Y +G +GEGS+ KVK D+ A+K+L + + R E +K+EI ++ +RH Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHR 108 Query: 371 NVVQLHEVMAS--KSKIYMVLEFVEGG--ELFDKIVNSGKLGEDEARRYFHQLINAVDYC 538 NV+QL +V+ + K K+YMV+E+ G E+ D + + +A YF QLI+ ++Y Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK-RFPVCQAHGYFRQLIDGLEYL 167 Query: 539 HSRGVYHRDLKPENLLLDSYGALKVSDFGLS-AFSPQTKDDGLLHTACGTPNYVAPEVLA 715 HS+G+ H+D+KP NLLL + G LK+SD G++ A P DD T+ G+P + PE+ Sbjct: 168 HSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDD-TCRTSQGSPAFQPPEIAN 226 Query: 716 D-KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLI 892 + G D+WS G+ L+ + G PF+ N+ L++ I R + + P +L+ Sbjct: 227 GLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGRGDFTIPCDCGPPLSDLL 286 Query: 893 KRILDPNPHTRITIAQILEDEWFKKDYKPPLSE 991 + +L+ P R +I QI + WF+K K PL+E Sbjct: 287 RGMLEYEPAKRFSIRQIRQHSWFRK--KHPLAE 317
>Q9P7I2:KCC1_SCHPO Calcium/calmodulin-dependent protein kinase type I -| Schizosaccharomyces pombe (Fission yeast) Length = 335 Score = 158 bits (399), Expect = 9e-38 Identities = 95/274 (34%), Positives = 148/274 (54%), Gaps = 9/274 (3%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLI--RH 367 Y +G+ +G G++A V+ A A K++++ + K + +K EIA +K + H Sbjct: 31 YRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKK--MMEKKQDFVKNEIAILKRVSYEH 88 Query: 368 PNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSR 547 PN++ L + + + +Y++ E GGELFD+I G E +A +AV Y H Sbjct: 89 PNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDN 148 Query: 548 GVYHRDLKPENLLL---DSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLAD 718 G+ HRDLKPENLL D L ++DFGLS F + +L TACGTP Y+APEV Sbjct: 149 GIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFY-EDSQYYMLMTACGTPEYMAPEVFRR 207 Query: 719 KGYDGMAADVWSCGIILFVLMAGYLPFDDPNLMTLYK--LISRANVSCPPW--FSTGARN 886 GY G D+W+ G+I + L++GY PF P+ + + + L + + P W S A++ Sbjct: 208 TGY-GKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAKD 266 Query: 887 LIKRILDPNPHTRITIAQILEDEWFKKDYKPPLS 988 IK+ L+ +P R+T A L+ F + +P S Sbjct: 267 FIKKCLENDPSKRLTAADALKHP-FLSEKRPATS 299
>O43293:DAPK3_HUMAN Death-associated protein kinase 3 - Homo sapiens (Human)| Length = 454 Score = 158 bits (399), Expect = 9e-38 Identities = 92/270 (34%), Positives = 148/270 (54%), Gaps = 13/270 (4%) Frame = +2 Query: 194 YELGKTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVL---RHKMVEQIKREIATMKLIR 364 YE+G+ +G G FA V+ + G A K + + + R E+I+RE+ ++ IR Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR 72 Query: 365 HPNVVQLHEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHS 544 HPN++ LH++ +K+ + ++LE V GGELFD + L EDEA ++ Q+++ V Y HS Sbjct: 73 HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132 Query: 545 RGVYHRDLKPENLLLDSYGA----LKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVL 712 + + H DLKPEN++L +K+ DFG+ + + + GTP +VAPE++ Sbjct: 133 KRIAHFDLKPENIMLLDKNVPNPRIKLIDFGI---AHKIEAGNEFKNIFGTPEFVAPEIV 189 Query: 713 ADKGYD--GMAADVWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWF----ST 874 Y+ G+ AD+WS G+I ++L++G PF IS N + S Sbjct: 190 ---NYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSE 246 Query: 875 GARNLIKRILDPNPHTRITIAQILEDEWFK 964 A++ I+R+L +P R+TIAQ LE W K Sbjct: 247 LAKDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>Q63484:AKT3_RAT RAC-gamma serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 479 Score = 158 bits (399), Expect = 9e-38 Identities = 84/241 (34%), Positives = 136/241 (56%) Frame = +2 Query: 206 KTIGEGSFAKVKVAKDTRNGATCAIKVLDRNHVLRHKMVEQIKREIATMKLIRHPNVVQL 385 K +G+G+F KV + ++ +G A+K+L + ++ V E +K RHP + L Sbjct: 152 KLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSL 211 Query: 386 HEVMASKSKIYMVLEFVEGGELFDKIVNSGKLGEDEARRYFHQLINAVDYCHSRGVYHRD 565 +K ++ V+E+V GGELF + ED R Y ++++A+DY HS + +RD Sbjct: 212 KYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRD 271 Query: 566 LKPENLLLDSYGALKVSDFGLSAFSPQTKDDGLLHTACGTPNYVAPEVLADKGYDGMAAD 745 LK ENL+LD G +K++DFGL D + T CGTP Y+APEVL D Y G A D Sbjct: 272 LKLENLMLDKDGHIKITDFGLC--KEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRAVD 328 Query: 746 VWSCGIILFVLMAGYLPFDDPNLMTLYKLISRANVSCPPWFSTGARNLIKRILDPNPHTR 925 W G++++ +M G LPF + + L++LI ++ P S+ A++L+ +L +P+ R Sbjct: 329 WWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKR 388 Query: 926 I 928 + Sbjct: 389 L 389 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 341,790,874 Number of extensions: 7956910 Number of successful extensions: 29184 Number of sequences better than 10.0: 2617 Number of HSP's gapped: 24641 Number of HSP's successfully gapped: 2731 Length of query: 629 Length of database: 100,686,439 Length adjustment: 119 Effective length of query: 510 Effective length of database: 68,045,334 Effective search space: 34703120340 Effective search space used: 34703120340 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
