Clone Information

BLAST Search Result

Clone Name	FLbaf11e14
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	P23901:ALDR_HORVU Aldose reductase - Hordeum vulgare (Barley)	270	7e-72
2	P45376:ALDR_MOUSE Aldose reductase - Mus musculus (Mouse)	253	1e-66
3	P07943:ALDR_RAT Aldose reductase - Rattus norvegicus (Rat)	251	4e-66
4	P16116:ALDR_BOVIN Aldose reductase - Bos taurus (Bovine)	251	6e-66
5	P15121:ALDR_HUMAN Aldose reductase - Homo sapiens (Human)	246	1e-64
6	P15122:ALDR_RABIT Aldose reductase - Oryctolagus cuniculus (Rabbit)	245	3e-64
7	Q9JII6:AK1A1_MOUSE Alcohol dehydrogenase [NADP+] - Mus musculus ...	245	3e-64
8	P80276:ALDR_PIG Aldose reductase - Sus scrofa (Pig)	244	5e-64
9	P51635:AK1A1_RAT Alcohol dehydrogenase [NADP+] - Rattus norvegic...	242	2e-63
10	P14550:AK1A1_HUMAN Alcohol dehydrogenase [NADP+] - Homo sapiens ...	242	3e-63
11	Q3ZCJ2:AK1A1_BOVIN Alcohol dehydrogenase [NADP+] - Bos taurus (B...	240	8e-63
12	P50578:AK1A1_PIG Alcohol dehydrogenase [NADP+] - Sus scrofa (Pig)	239	2e-62
13	Q10494:YDG7_SCHPO Probable oxidoreductase C26F1.07 - Schizosacch...	233	1e-60
14	P27800:ALDX_SPOSA Aldehyde reductase 1 - Sporobolomyces salmonic...	228	4e-59
15	Q9DCT1:AK1E1_MOUSE Aldo-keto reductase family 1 member E1 - Mus ...	225	3e-58
16	Q7G764:NADO1_ORYSJ Probable NAD(P)H-dependent oxidoreductase 1 -...	224	7e-58
17	O94735:XYL1_PICGU NADPH-dependent D-xylose reductase - Pichia gu...	223	1e-57
18	Q7G765:NADO2_ORYSJ Probable NAD(P)H-dependent oxidoreductase 2 -...	219	1e-56
19	P26690:6DCS_SOYBN NAD(P)H-dependent 6'-deoxychalcone synthase - ...	219	1e-56
20	P21300:ALD1_MOUSE Aldose reductase-related protein 1 - Mus muscu...	219	2e-56
21	P45377:ALD2_MOUSE Aldose reductase-related protein 2 - Mus muscu...	217	7e-56
22	O08782:ALD2_CRIGR Aldose reductase-related protein 2 - Cricetulu...	217	7e-56
23	P14065:GCY_YEAST Protein GCY - Saccharomyces cerevisiae (Baker's...	217	9e-56
24	O60218:AK1BA_HUMAN Aldo-keto reductase family 1 member B10 - Hom...	216	1e-55
25	Q9P430:XYL1_CANSH NAD(P)H-dependent D-xylose reductase - Candida...	214	6e-55
26	P70694:DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 - Mus muscul...	213	1e-54
27	Q5REQ0:AK1C1_PONPY Aldo-keto reductase family 1 member C1 homolo...	211	5e-54
28	P80508:PE2R_RABIT Prostaglandin-E(2) 9-reductase - Oryctolagus c...	210	1e-53
29	Q95JH6:AK1C1_MACFU Aldo-keto reductase family 1 member C1 homolo...	209	1e-53
30	P87039:XYL2_CANTR NADPH-dependent D-xylose reductase II,III - Ca...	209	2e-53
31	Q04828:AK1C1_HUMAN Aldo-keto reductase family 1 member C1 - Homo...	209	2e-53
32	P78736:XYL1_PACTA NAD(P)H-dependent D-xylose reductase - Pachyso...	207	5e-53
33	P31867:XYL1_PICST NAD(P)H-dependent D-xylose reductase - Pichia ...	207	7e-53
34	O13283:XYL1_CANTR NAD(P)H-dependent D-xylose reductase I,II - Ca...	207	7e-53
35	Q95JH7:AK1C1_MACFA Aldo-keto reductase family 1 member C1 homolo...	207	7e-53
36	P52895:AK1C2_HUMAN Aldo-keto reductase family 1 member C2 - Homo...	206	1e-52
37	P17516:AK1C4_HUMAN Aldo-keto reductase family 1 member C4 - Homo...	203	1e-51
38	O74237:XYL1_CANTE NAD(P)H-dependent D-xylose reductase - Candida...	202	3e-51
39	P31210:AK1D1_RAT 3-oxo-5-beta-steroid 4-dehydrogenase - Rattus n...	202	3e-51
40	Q5R7C9:AK1C3_PONPY Aldo-keto reductase family 1 member C3 homolo...	201	7e-51
41	P42330:AK1C3_HUMAN Aldo-keto reductase family 1 member C3 - Homo...	201	7e-51
42	P52898:DDBX_BOVIN Dihydrodiol dehydrogenase 3 - Bos taurus (Bovine)	200	9e-51
43	P05980:PGFS1_BOVIN Prostaglandin-F synthase 1 - Bos taurus (Bovine)	200	1e-50
44	P49378:XYL1_KLULA NAD(P)H-dependent D-xylose reductase - Kluyver...	199	3e-50
45	P52897:PGFS2_BOVIN Prostaglandin-F synthase 2 - Bos taurus (Bovine)	198	3e-50
46	Q95JH5:AK1C4_MACFA Aldo-keto reductase family 1 member C4 - Maca...	198	3e-50
47	Q6Y0Z3:XYL1_CANPA NADH-dependent D-xylose reductase - Candida pa...	197	7e-50
48	Q9P8R5:XYL1_ASPNG NAD(P)H-dependent D-xylose reductase - Aspergi...	197	7e-50
49	O70473:AK1A1_CRIGR Alcohol dehydrogenase [NADP+] - Cricetulus gr...	197	7e-50
50	Q12458:YPR1_YEAST Putative reductase 1 - Saccharomyces cerevisia...	197	1e-49
51	P22045:P100_LEIMA Probable reductase - Leishmania major	197	1e-49
52	P51652:AKC1H_RAT Aldo-keto reductase family 1 member C18 - Rattu...	197	1e-49
53	Q95JH4:AK1C4_MACFU Aldo-keto reductase family 1 member C4 - Maca...	197	1e-49
54	P51857:AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogenase - Homo s...	196	2e-49
55	Q96JD6:AKCL2_HUMAN Aldo-keto reductase family 1 member C-like pr...	195	3e-49
56	Q4R802:AKCL2_MACFA Aldo-keto reductase family 1 member C-like pr...	194	6e-49
57	Q8K023:AKC1H_MOUSE Aldo-keto reductase family 1 member C18 - Mus...	192	2e-48
58	Q876L8:XYL1_TRIRE NAD(P)H-dependent D-xylose reductase - Trichod...	191	4e-48
59	Q8VCX1:AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogenase - Mus mu...	188	3e-47
60	P28475:S6PD_MALDO NADP-dependent D-sorbitol-6-phosphate dehydrog...	188	4e-47
61	P02532:CRO_RANTE Rho crystallin - Rana temporaria (European comm...	187	6e-47
62	P17264:CRO_RANCA Rho crystallin - Rana catesbeiana (Bull frog)	185	3e-46
63	P23457:DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase - Rattus no...	184	5e-46
64	P38715:GRE3_YEAST NADPH-dependent aldose reductase GRE3 - Saccha...	183	1e-45
65	Q9TV64:AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogenase - Orycto...	183	1e-45
66	Q01213:DTDH_MUCMU 4-dihydromethyl-trisporate dehydrogenase - Muc...	182	2e-45
67	Q8VC28:AK1CD_MOUSE Aldo-keto reductase family 1 member C13 - Mus...	179	2e-44
68	P06632:DKGA_CORSC 2,5-diketo-D-gluconic acid reductase A - Coryn...	178	4e-44
69	Q46857:DKGA_ECOLI 2,5-diketo-D-gluconic acid reductase A - Esche...	171	6e-42
70	Q8XBT6:DKGA_ECO57 2,5-diketo-D-gluconic acid reductase A - Esche...	169	2e-41
71	Q8ZM06:DKGA_SALTY 2,5-diketo-D-gluconic acid reductase A - Salmo...	166	2e-40
72	P82809:AK1CD_MESAU Aldo-keto reductase family 1 member C13 - Mes...	165	4e-40
73	Q02198:MORA_PSEPU Morphine 6-dehydrogenase - Pseudomonas putida	164	7e-40
74	Q8ZI40:DKGA_YERPE 2,5-diketo-D-gluconic acid reductase A - Yersi...	163	1e-39
75	P58744:DKGA_SALTI 2,5-diketo-D-gluconic acid reductase A - Salmo...	163	1e-39
76	P38115:ARA1_YEAST D-arabinose dehydrogenase [NAD(P)+] heavy chai...	160	1e-38
77	Q09632:YOF5_CAEEL Probable oxidoreductase ZK1290.5 - Caenorhabdi...	158	4e-38
78	P47137:YJ66_YEAST Probable oxidoreductase YJR096W - Saccharomyce...	150	8e-36
79	P15339:DKGB_CORSS 2,5-diketo-D-gluconic acid reductase B - Coryn...	148	4e-35
80	Q5T2L2:AKCL1_HUMAN Aldo-keto reductase family 1 member C-like pr...	144	6e-34
81	Q8X7Z7:DKGB_ECO57 2,5-diketo-D-gluconic acid reductase B - Esche...	139	2e-32
82	Q8ZRM7:DKGB_SALTY 2,5-diketo-D-gluconic acid reductase B - Salmo...	139	3e-32
83	Q8Z988:DKGB_SALTI 2,5-diketo-D-gluconic acid reductase B - Salmo...	138	5e-32
84	Q8ZH36:DKGB_YERPE 2,5-diketo-D-gluconic acid reductase B - Yersi...	137	7e-32
85	P30863:DKGB_ECOLI 2,5-diketo-D-gluconic acid reductase B - Esche...	137	9e-32
86	Q07551:KAR_YEAST NADPH-dependent alpha-keto amide reductase - Sa...	119	3e-26
87	P82125:AFR_PIG 1,5-anhydro-D-fructose reductase - Sus scrofa (Pig)	99	5e-20
88	P76234:YEAE_ECOLI Uncharacterized protein yeaE - Escherichia coli	87	2e-16
89	P80874:GS69_BACSU General stress protein 69 - Bacillus subtilis	78	8e-14
90	P25906:YDBC_ECOLI Putative oxidoreductase ydbC - Escherichia coli	64	1e-09
91	Q9PWR1:KCAB1_CHICK Voltage-gated potassium channel subunit beta-...	63	2e-09
92	P77256:YDJG_ECOLI Uncharacterized oxidoreductase ydjG - Escheric...	62	4e-09
93	P63144:KCAB1_RAT Voltage-gated potassium channel subunit beta-1 ...	62	6e-09
94	Q28528:KCAB1_MUSPU Voltage-gated potassium channel subunit beta-...	62	6e-09
95	P63143:KCAB1_MOUSE Voltage-gated potassium channel subunit beta-...	62	6e-09
96	Q4PJK1:KCAB1_BOVIN Voltage-gated potassium channel subunit beta-...	62	6e-09
97	Q94A68:Y1669_ARATH Putative oxidoreductase At1g06690, chloroplas...	60	2e-08
98	Q9XT31:KCAB1_RABIT Voltage-gated potassium channel subunit beta-...	59	4e-08
99	Q14722:KCAB1_HUMAN Voltage-gated potassium channel subunit beta-...	59	4e-08
100	P46905:YCCK_BACSU Uncharacterized oxidoreductase yccK - Bacillus...	57	1e-07
101	P46336:IOLS_BACSU Protein iolS - Bacillus subtilis	55	6e-07
102	P76187:YDHF_ECOLI Oxidoreductase ydhF - Escherichia coli	55	8e-07
103	P63485:Y2320_MYCBO Uncharacterized oxidoreductase Mb2320 - Mycob...	54	1e-06
104	P63484:Y2298_MYCTU Uncharacterized oxidoreductase Rv2298/MT2355 ...	54	1e-06
105	Q9PTM4:KCAB3_XENLA Voltage-gated potassium channel subunit beta-...	54	2e-06
106	Q9PTM5:KCAB2_XENLA Voltage-gated potassium channel subunit beta-...	53	2e-06
107	P62483:KCAB2_RAT Voltage-gated potassium channel subunit beta-2 ...	53	2e-06
108	P62482:KCAB2_MOUSE Voltage-gated potassium channel subunit beta-...	53	2e-06
109	P40691:A115_TOBAC Auxin-induced protein PCNT115 - Nicotiana taba...	53	2e-06
110	P42972:YCSN_BACSU Uncharacterized oxidoreductase ycsN - Bacillus...	52	4e-06
111	Q09923:YAKC_SCHPO Aldo-keto reductase yakc [NADP+] - Schizosacch...	52	4e-06
112	P0A9T5:TAS_SHIFL Protein tas - Shigella flexneri	52	5e-06
113	P0A9T4:TAS_ECOLI Protein tas - Escherichia coli	52	5e-06
114	Q13303:KCAB2_HUMAN Voltage-gated potassium channel subunit beta-...	51	1e-05
115	P49249:IN22_MAIZE IN2-2 protein - Zea mays (Maize)	50	1e-05
116	Q27955:KCAB2_BOVIN Voltage-gated potassium channel subunit beta-...	50	2e-05
117	Q40648:KCAB_ORYSJ Probable voltage-gated potassium channel subun...	50	2e-05
118	Q63494:KCAB3_RAT Voltage-gated potassium channel subunit beta-3 ...	49	3e-05
119	O43448:KCAB3_HUMAN Voltage-gated potassium channel subunit beta-...	45	8e-04
120	P77735:YAJO_ECOLI Uncharacterized oxidoreductase yajO - Escheric...	43	0.003
121	Q8CG76:ARK72_MOUSE Aflatoxin B1 aldehyde reductase member 2 - Mu...	42	0.005
122	P40690:ALKE_BABBO Aldo-keto reductase - Babesia bovis	42	0.007
123	P82810:MORA_RABIT Morphine 6-dehydrogenase - Oryctolagus cunicul...	41	0.011
124	Q46851:YGHZ_ECOLI Uncharacterized protein yghZ - Escherichia coli	40	0.015
125	Q8X529:YGHZ_ECO57 Uncharacterized protein yghZ - Escherichia col...	40	0.019
126	P38918:ARK73_RAT Aflatoxin B1 aldehyde reductase member 3 - Ratt...	40	0.019
127	Q8CG45:ARK72_RAT Aflatoxin B1 aldehyde reductase member 2 - Ratt...	40	0.019
128	P54569:YQKF_BACSU Uncharacterized oxidoreductase yqkF - Bacillus...	40	0.025
129	P49261:CROB_LEPLU Rho beta-crystallin - Lepidodactylus lugubris ...	39	0.033
130	Q8NHP1:ARK74_HUMAN Aflatoxin B1 aldehyde reductase member 4 - Ho...	38	0.097
131	P55804:DHGP_ASPNG NADP(+)-dependent glycerol dehydrogenase - Asp...	37	0.16
132	Q32NM7:ILDR1_XENLA Immunoglobulin-like domain-containing recepto...	37	0.22
133	O43488:ARK72_HUMAN Aflatoxin B1 aldehyde reductase member 2 - Ho...	36	0.28
134	O95154:ARK73_HUMAN Aflatoxin B1 aldehyde reductase member 3 - Ho...	36	0.37
135	P48507:GSH0_HUMAN Glutamate--cysteine ligase regulatory subunit ...	35	0.48
136	Q00049:NORA_ASPFL Norsolorinic acid reductase - Aspergillus flavus	35	0.63
137	P43547:AAD6_YEAST Putative aryl-alcohol dehydrogenase AAD6 - Sac...	35	0.63
138	Q00258:NORA_ASPPA Norsolorinic acid reductase - Aspergillus para...	35	0.82
139	O09172:GSH0_MOUSE Glutamate--cysteine ligase regulatory subunit ...	35	0.82
140	P42884:AAD14_YEAST Putative aryl-alcohol dehydrogenase AAD14 - S...	35	0.82
141	P48508:GSH0_RAT Glutamate--cysteine ligase regulatory subunit - ...	34	1.1
142	Q2T9Y6:GSH0_BOVIN Glutamate--cysteine ligase regulatory subunit ...	34	1.4
143	Q07747:AAD4_YEAST Probable aryl-alcohol dehydrogenase AAD4 - Sac...	34	1.4
144	Q05514:MAAL_CLOTT Methylaspartate ammonia-lyase - Clostridium te...	33	3.1
145	P25612:AAD3_YEAST Putative aryl-alcohol dehydrogenase AAD3 - Sac...	32	5.3
146	P47182:AAD10_YEAST Putative aryl-alcohol dehydrogenase AAD10 - S...	32	6.9
147	Q80T03:MUC6_MOUSE Mucin-6 precursor - Mus musculus (Mouse)	32	7.0
148	Q00727:STCV_EMENI Putative sterigmatocystin biosynthesis dehydro...	31	9.1
149	Q63563:ABCC9_RAT ATP-binding cassette transporter sub-family C m...	31	9.1
150	P70170:ABCC9_MOUSE ATP-binding cassette transporter sub-family C...	31	9.1
151	Q01752:AAD_PHACH Aryl-alcohol dehydrogenase [NADP+] - Phanerocha...	31	9.1
152	Q09134:GRPA_MEDFA Abscisic acid and environmental stress-inducib...	31	9.1

>P23901:ALDR_HORVU Aldose reductase - Hordeum vulgare (Barley)|
          Length = 320
 Score =  270 bits (691), Expect = 7e-72
 Identities = 143/325 (44%), Positives = 197/325 (60%), Gaps = 5/325 (1%)
 Frame = +2

Query: 26  ARALASVGERQGMALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQV 205
           A A A++G  QG   HFVL +G  +P+VGLGTW++          A  +AGYRH+D A  
Sbjct: 2   ASAKATMG--QGEQDHFVLKSGHAMPAVGLGTWRAGSDTAHSVRTAITEAGYRHVDTAAE 59

Query: 206 YGNEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLY 385
           YG EKE+G  LK   + G+  RKDLF+TSK+WCTN APE V  AL+ TL+DLQ DY+DLY
Sbjct: 60  YGVEKEVGKGLKAAMEAGID-RKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLY 118

Query: 386 LVHWPIRMKKGAGFNPE--NVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLA 559
            +HWP R+K GA   PE   V+  D+   W  ME+L   G  + IGV N++  K+  LL 
Sbjct: 119 HIHWPFRLKDGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLR 178

Query: 560 VARVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTA 739
            A++ PA  Q+E HP W+  K+ + C   GIH +AYSPLGS       ++   PVV   A
Sbjct: 179 SAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHVTAYSPLGS----SEKNLAHDPVVEKVA 234

Query: 740 EKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEI-EQAKL 916
            KL KTP QV ++W +Q G SV+PKS+ +ERI+ NI V+ W IP + F     I ++ ++
Sbjct: 235 NKLNKTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRV 294

Query: 917 IRGK--FWTHPEGVFKSEEEIWDGE 985
           + G+  F     G ++S  ++WD E
Sbjct: 295 LTGEELFVNKTHGPYRSAADVWDHE 319

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>P45376:ALDR_MOUSE Aldose reductase - Mus musculus (Mouse)|
          Length = 316

 Score =  253 bits (646), Expect = 1e-66
 Identities = 139/284 (48%), Positives = 174/284 (61%), Gaps = 12/284 (4%)
 Frame = +2

Query: 62  MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           MA H  LN G K+P++GLGTW+S PG V +AV  A+  GYRHIDCAQVY NEKE+G AL+
Sbjct: 1   MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQ 60

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 421
           +   E V  R+DLFI SKLWCT H    V  A   TL DLQ DY+DLYL+HWP   K G 
Sbjct: 61  EKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGP 120

Query: 422 GFNP----ENVIPA--DIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTP 577
            + P     NVIP+  D   TW AME L D G  + IGVSNF+  ++E +L     +  P
Sbjct: 121 DYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKP 180

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF----SVLEHPVVVSTAEK 745
           A NQ+ECHP   Q KL + C SKGI  +AYSPLGSP    A     S+LE P + + A K
Sbjct: 181 AVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
             KT AQV +R+ +Q    V+PKS    RI  N+ V+D+ +  +
Sbjct: 241 YNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSE 284

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>P07943:ALDR_RAT Aldose reductase - Rattus norvegicus (Rat)|
          Length = 316

 Score =  251 bits (641), Expect = 4e-66
 Identities = 139/284 (48%), Positives = 172/284 (60%), Gaps = 12/284 (4%)
 Frame = +2

Query: 62  MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           MA H  LN G K+P++GLGTW+S PG V +AV  A+  GYRHIDCAQVY NEKE+G AL+
Sbjct: 1   MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQ 60

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 421
           +   E V  R+DLFI SKLWCT H    V  A   TL DLQ DY+DLYL+HWP   K G 
Sbjct: 61  EKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGP 120

Query: 422 GFNP----ENVIPA--DIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTP 577
            + P     NVIP+  D   TW AME L D G  +AIGVSNF+  ++E +L     +  P
Sbjct: 121 DYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKP 180

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF----SVLEHPVVVSTAEK 745
           A NQ+ECHP   Q KL + C  KGI  +AYSPLGSP    A     S+LE P +   A K
Sbjct: 181 AVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAK 240

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
             KT AQV +R+ +Q    V+PKS    RI  N  V+D+ +  +
Sbjct: 241 YNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNE 284

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>P16116:ALDR_BOVIN Aldose reductase - Bos taurus (Bovine)|
          Length = 315

 Score =  251 bits (640), Expect = 6e-66
 Identities = 140/280 (50%), Positives = 173/280 (61%), Gaps = 12/280 (4%)
 Frame = +2

Query: 65  ALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKK 244
           A + VL TGAK+P +GLGTW+S PG V +AV  A+  GYRHIDCA VY NE E+G AL+ 
Sbjct: 1   AHNIVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQA 60

Query: 245 VFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAG 424
              E V  R+DLFI SKLWCT H  + V  A   TL DL+ DY+DLYL+HWP   K G  
Sbjct: 61  KLQEQVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKD 120

Query: 425 FNP----ENVIPA--DIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPA 580
           F P     NVIP+  D   TW AME L D G  +AIGVSNF+  +VE++L     +  PA
Sbjct: 121 FFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPA 180

Query: 581 ANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF----SVLEHPVVVSTAEKL 748
            NQ+ECHP   Q KL   C SKGI  +AYSPLGSP    A     S+LE P + + A+K 
Sbjct: 181 VNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKY 240

Query: 749 GKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI 868
            KT AQV +R+ +Q    V+PKS   ERI  N  V+D+ +
Sbjct: 241 NKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFDFEL 280

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>P15121:ALDR_HUMAN Aldose reductase - Homo sapiens (Human)|
          Length = 316

 Score =  246 bits (628), Expect = 1e-64
 Identities = 138/281 (49%), Positives = 173/281 (61%), Gaps = 12/281 (4%)
 Frame = +2

Query: 62  MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           MA   +LN GAK+P +GLGTW+S PG V +AV  A+  GYRHIDCA VY NE E+G A++
Sbjct: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 421
           +   E V  R++LFI SKLWCT H    V  A   TL DL+ DY+DLYL+HWP   K G 
Sbjct: 61  EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120

Query: 422 GFNP----ENVIPAD--IPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTP 577
            F P     NV+P+D  I  TWAAME L D G  +AIG+SNF+  +VE +L     +  P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF----SVLEHPVVVSTAEK 745
           A NQ+ECHP   Q KL   C SKGI  +AYSPLGSP    A     S+LE P + + A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI 868
             KT AQV +R+ +Q    V+PKS   ERI  N  V+D+ +
Sbjct: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFEL 281

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>P15122:ALDR_RABIT Aldose reductase - Oryctolagus cuniculus (Rabbit)|
          Length = 316

 Score =  245 bits (625), Expect = 3e-64
 Identities = 136/284 (47%), Positives = 174/284 (61%), Gaps = 12/284 (4%)
 Frame = +2

Query: 62  MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           MA H VL  GAK+P +GLGTW+S PG V +AV  A+  GYRHIDCA VY NE E+G AL+
Sbjct: 1   MATHLVLYNGAKMPILGLGTWKSPPGQVTEAVKTAIDLGYRHIDCAHVYQNENEVGVALQ 60

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 421
           +   E V  R++LFI SKLWCT+H    V  A   TL DL+ DY+DLYL+HWP   K G+
Sbjct: 61  EKLKEQVVKREELFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGS 120

Query: 422 GFNP----ENVIPADIP--ATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTP 577
            + P     NVIP+D     TW AME L D G  ++IGVSNF+  ++E +L     +  P
Sbjct: 121 EYFPLDAAGNVIPSDTDFLDTWEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKP 180

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF----SVLEHPVVVSTAEK 745
           A NQ+ECHP   Q KL   C SKGI  +AYSPLGSP    A     S+LE P + + A+K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIADK 240

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
             KT AQV +R+ +Q    V+PKS    RI  N  V+D+ +  +
Sbjct: 241 HKKTTAQVLIRFPMQRNLVVIPKSVTPARIAENFQVFDFELSSE 284

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>Q9JII6:AK1A1_MOUSE Alcohol dehydrogenase [NADP+] - Mus musculus (Mouse)|
          Length = 325

 Score =  245 bits (625), Expect = 3e-64
 Identities = 132/276 (47%), Positives = 179/276 (64%), Gaps = 13/276 (4%)
 Frame = +2

Query: 77  VLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDE 256
           +L+TG K+P +GLGTW+SEPG V  A+  A+ AGYRHIDCA VYGNE EIG ALK+    
Sbjct: 7   LLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGS 66

Query: 257 G-VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 433
           G    R++LF+TSKLW T H PEDV  AL  TL DLQ +Y+DLYL+HWP   ++G    P
Sbjct: 67  GKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFP 126

Query: 434 ENV------IPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVE 595
           +N              TW A+E L   G  +A+G+SNF+ ++++++L+VA V PA  QVE
Sbjct: 127 KNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVE 186

Query: 596 CHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS------VLEHPVVVSTAEKLGKT 757
           CHP   Q +L   C ++G+  +AYSPLGS  + +A+       +LE PVV++ AEK G++
Sbjct: 187 CHPYLAQNELIAHCHARGLEVTAYSPLGS--SDRAWRHPDEPVLLEEPVVLALAEKHGRS 244

Query: 758 PAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWS 865
           PAQ+ LRW VQ     +PKS N  RI  NI V+D++
Sbjct: 245 PAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFT 280

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>P80276:ALDR_PIG Aldose reductase - Sus scrofa (Pig)|
          Length = 316

 Score =  244 bits (623), Expect = 5e-64
 Identities = 139/286 (48%), Positives = 175/286 (61%), Gaps = 13/286 (4%)
 Frame = +2

Query: 62  MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           MA H VL TGAK+P +GLGTW+S PG V +AV  A+  GYRHIDCA VY NE E+G  L+
Sbjct: 1   MASHLVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQ 60

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 421
           +     V  R+DLFI SKLWCT+H    V  A   TL+DL+ DY+DLYL+HWP   K G 
Sbjct: 61  EKLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGK 120

Query: 422 GFNP----ENVIP--ADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTP 577
              P     NV+P  +D   TW AME L D G  +AIGVSNF+  +VE++L     +  P
Sbjct: 121 DPFPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKP 180

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF----SVLEHPVVVSTAEK 745
           A NQ+E HP   Q KL + C SKGI  +AYSPLGSP    A     S+LE P + + A K
Sbjct: 181 AVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI-PGDL 880
             KT AQV +R+ +Q    V+PKS   ERI  N  V+D+ + P D+
Sbjct: 241 YNKTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDM 286

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>P51635:AK1A1_RAT Alcohol dehydrogenase [NADP+] - Rattus norvegicus (Rat)|
          Length = 325

 Score =  242 bits (618), Expect = 2e-63
 Identities = 130/276 (47%), Positives = 178/276 (64%), Gaps = 13/276 (4%)
 Frame = +2

Query: 77  VLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDE 256
           +L+TG K+P +GLGTW+SEPG V  A+  A+  GYRHIDCA VYGNE EIG ALK+    
Sbjct: 7   LLHTGQKMPLIGLGTWKSEPGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKESVGA 66

Query: 257 G-VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 433
           G    R++LF+TSKLW T H PEDV  A+  TL DLQ +Y+DLYL+HWP   ++G    P
Sbjct: 67  GKAVPREELFVTSKLWNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAFERGDNPFP 126

Query: 434 ENV------IPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVE 595
           +N              TW A+E+L   G  +A+G+SNFS ++++++L+VA V PA  QVE
Sbjct: 127 KNADGTVKYDSTHYKETWKALEALVAKGLVKALGLSNFSSRQIDDVLSVASVRPAVLQVE 186

Query: 596 CHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS------VLEHPVVVSTAEKLGKT 757
           CHP   Q +L   C ++G+  +AYSPLGS  + +A+       +LE PVV++ AEK G++
Sbjct: 187 CHPYLAQNELIAHCQARGLEVTAYSPLGS--SDRAWRHPDEPVLLEEPVVLALAEKHGRS 244

Query: 758 PAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWS 865
           PAQ+ LRW VQ     +PKS    RI  NI V+D++
Sbjct: 245 PAQILLRWQVQRKVICIPKSITPSRILQNIQVFDFT 280

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>P14550:AK1A1_HUMAN Alcohol dehydrogenase [NADP+] - Homo sapiens (Human)|
          Length = 325

 Score =  242 bits (617), Expect = 3e-63
 Identities = 130/276 (47%), Positives = 178/276 (64%), Gaps = 13/276 (4%)
 Frame = +2

Query: 77  VLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDE 256
           +L+TG K+P +GLGTW+SEPG V  AV  A+  GYRHIDCA +YGNE EIG ALK+    
Sbjct: 7   LLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66

Query: 257 G-VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 433
           G    R++LF+TSKLW T H PEDV  AL  TL DLQ +Y+DLYL+HWP   ++G    P
Sbjct: 67  GKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFP 126

Query: 434 ENV------IPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVE 595
           +N              TW A+E+L   G  +A+G+SNF+ ++++++L+VA V PA  QVE
Sbjct: 127 KNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVE 186

Query: 596 CHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS------VLEHPVVVSTAEKLGKT 757
           CHP   Q +L   C ++G+  +AYSPLGS  + +A+       +LE PVV++ AEK G++
Sbjct: 187 CHPYLAQNELIAHCQARGLEVTAYSPLGS--SDRAWRDPDEPVLLEEPVVLALAEKYGRS 244

Query: 758 PAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWS 865
           PAQ+ LRW VQ     +PKS    RI  NI V+D++
Sbjct: 245 PAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFT 280

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>Q3ZCJ2:AK1A1_BOVIN Alcohol dehydrogenase [NADP+] - Bos taurus (Bovine)|
          Length = 325

 Score =  240 bits (613), Expect = 8e-63
 Identities = 127/274 (46%), Positives = 176/274 (64%), Gaps = 11/274 (4%)
 Frame = +2

Query: 77  VLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDE 256
           +L+TG K+P +GLGTW+S+PG V  A+  A+  GYRHIDCA +YGNE EIG ALK+    
Sbjct: 7   LLHTGQKMPLIGLGTWKSDPGQVKAAIKYALSVGYRHIDCAAIYGNETEIGEALKENVGP 66

Query: 257 G-VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 433
           G +  R++LF+TSKLW T H PEDV  AL  TL DLQ +Y+DLYL+HWP   ++G    P
Sbjct: 67  GKLVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDSPFP 126

Query: 434 ENV------IPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVE 595
           +N              TW A+E+L   G  RA+G+SNF+ ++++++L+VA V PA  QVE
Sbjct: 127 KNADGTIRYDSTHYKETWRALEALVAKGLVRALGLSNFNSRQIDDVLSVASVRPAVLQVE 186

Query: 596 CHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTF----KAFSVLEHPVVVSTAEKLGKTPA 763
           CHP   Q +L   C ++ +  +AYSPLGS        +   +L+ PVV++ AEK G++PA
Sbjct: 187 CHPYLAQNELIAHCQARNLEVTAYSPLGSSDRAWRDPEEPVLLKEPVVLALAEKHGRSPA 246

Query: 764 QVALRWGVQAGHSVLPKSTNEERIRANIDVYDWS 865
           Q+ LRW VQ   S +PKS    RI  NI V+D++
Sbjct: 247 QILLRWQVQRKVSCIPKSVTPSRILENIQVFDFT 280

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>P50578:AK1A1_PIG Alcohol dehydrogenase [NADP+] - Sus scrofa (Pig)|
          Length = 325

 Score =  239 bits (609), Expect = 2e-62
 Identities = 129/276 (46%), Positives = 175/276 (63%), Gaps = 13/276 (4%)
 Frame = +2

Query: 77  VLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDE 256
           +L+TG K+P +GLGTW+SEPG V  A+  A+  GYRHIDCA +YGNE EIG AL +    
Sbjct: 7   LLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIYGNELEIGEALTETVGP 66

Query: 257 G-VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 433
           G    R++LF+TSKLW T H PEDV  AL  TL DLQ +Y+DLYL+HWP   ++G    P
Sbjct: 67  GKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFP 126

Query: 434 ENVI------PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVE 595
           +N              TW A+E+L   G  RA+G+SNFS ++++++L+VA V PA  QVE
Sbjct: 127 KNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRPAVLQVE 186

Query: 596 CHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS------VLEHPVVVSTAEKLGKT 757
           CHP   Q +L   C ++G+  +AYSPLGS  + +A+       +LE PVV + AEK  ++
Sbjct: 187 CHPYLAQNELIAHCQARGLEVTAYSPLGS--SDRAWRDPNEPVLLEEPVVQALAEKYNRS 244

Query: 758 PAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWS 865
           PAQ+ LRW VQ     +PKS    RI  NI V+D++
Sbjct: 245 PAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFT 280

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>Q10494:YDG7_SCHPO Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe|
           (Fission yeast)
          Length = 321

 Score =  233 bits (594), Expect = 1e-60
 Identities = 123/270 (45%), Positives = 169/270 (62%), Gaps = 11/270 (4%)
 Frame = +2

Query: 68  LHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKV 247
           +HF L  G+KIP +GLGTW+SEP    +AV  A++ GYRHID A +YGNE E+G  +K  
Sbjct: 14  VHFTLADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK-- 71

Query: 248 FDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGF 427
             E    RKD+++TSKLWC  HAPE VP AL+ TL+DL+ DY+D YL+HWP+  K G   
Sbjct: 72  --ESGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDK 129

Query: 428 NPE----NVI--PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQ 589
            P+    N+I     I  TW AME L ++GK R IG+SNF+   +E +L VA+V PA +Q
Sbjct: 130 FPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQ 189

Query: 590 VECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTF---KAFSVLEHPVVVSTAEKLGK-- 754
           +E HP   Q +  +     GIH +AYSP G+  T    K   ++EH  +   A+  G+  
Sbjct: 190 MELHPFLPQTEFVEKHKKLGIHVTAYSPFGNQNTIYESKIPKLIEHETIQKIAKSKGEGV 249

Query: 755 TPAQVALRWGVQAGHSVLPKSTNEERIRAN 844
           T A +A+ W +  G SV+PKS NE+RI++N
Sbjct: 250 TGATIAVSWAITRGTSVIPKSVNEQRIKSN 279

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>P27800:ALDX_SPOSA Aldehyde reductase 1 - Sporobolomyces salmonicolor|
          Length = 323

 Score =  228 bits (581), Expect = 4e-59
 Identities = 122/267 (45%), Positives = 161/267 (60%), Gaps = 12/267 (4%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LNTGA +  VG GTWQ+ PG VG  V  A++ GYRH+D A+VY N+ E+G A+K    E 
Sbjct: 7   LNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK----EA 62

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPEN 439
              R+DLFITSKLW  +H PE V  ALD TL++L  +Y+DLYL+HWP+      G   +N
Sbjct: 63  GVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPP-EGDITQN 121

Query: 440 VIP------------ADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAA 583
           + P              +  TW AM  L D+GK +AIGVSNF  K V+ ++    VTP+ 
Sbjct: 122 LFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGVTPSV 181

Query: 584 NQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPA 763
           NQ+E HP+  Q +L     +K IH +AYSPLG+  T  A  +++HP +   AEK G TPA
Sbjct: 182 NQIERHPLLLQPELIAHHKAKNIHITAYSPLGN-NTVGAPLLVQHPEIKRIAEKNGCTPA 240

Query: 764 QVALRWGVQAGHSVLPKSTNEERIRAN 844
           QV + W +  GHSV+PKS    RI  N
Sbjct: 241 QVLIAWAIVGGHSVIPKSVTPSRIGEN 267

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>Q9DCT1:AK1E1_MOUSE Aldo-keto reductase family 1 member E1 - Mus musculus (Mouse)|
          Length = 301

 Score =  225 bits (573), Expect = 3e-58
 Identities = 120/270 (44%), Positives = 159/270 (58%), Gaps = 13/270 (4%)
 Frame = +2

Query: 98  IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 277
           IP+VGLGTW++ PG V DAV  A+  GYRH DCA +Y NE E+G  + +   EGV  R+D
Sbjct: 4   IPTVGLGTWKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKRED 63

Query: 278 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPAD- 454
           LF+ SKLWCT H    V  A   TL+ L  DY+DLYL+HWP+  K G     E  IP D 
Sbjct: 64  LFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFKPG-----EKDIPLDR 118

Query: 455 ----IPA------TWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAANQVEC 598
               IP+      TW AME L   G  + +GVSNF+ +++E LL     RV P  NQ+EC
Sbjct: 119 NGKVIPSHTSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIEC 178

Query: 599 HPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALR 778
           HP   Q KL D C  + +  +AY PLG  G    F +++  V+   A+K GK+PAQ+ +R
Sbjct: 179 HPYLNQKKLIDFCHKRNVSVTAYRPLGGSG--GGFHLMDDTVIRKIAKKHGKSPAQILIR 236

Query: 779 WGVQAGHSVLPKSTNEERIRANIDVYDWSI 868
           + +Q    V+PKS    RIR NI V+D+ +
Sbjct: 237 FQIQRNLIVIPKSVTPSRIRENIQVFDFEL 266

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>Q7G764:NADO1_ORYSJ Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp.|
           japonica (Rice)
          Length = 321

 Score =  224 bits (570), Expect = 7e-58
 Identities = 123/309 (39%), Positives = 190/309 (61%), Gaps = 12/309 (3%)
 Frame = +2

Query: 98  IPSVGLGT-----WQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG- 259
           +P VG+GT       SE      A+  A++ GYRH D A++Y  E  +G A+ +    G 
Sbjct: 16  MPRVGMGTAAFPFTSSEDTTA--AMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGL 73

Query: 260 VTTRKDLFITSKLWCTN-HAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA---GF 427
           + +R D+F+TSK+WC++ HA   VP A + TL++L  DYVDL LVHWP+ +  G     F
Sbjct: 74  IASRADVFVTSKIWCSDLHAGRVVPAARE-TLRNLGMDYVDLLLVHWPVSLTPGNYDFPF 132

Query: 428 NPENVIPA-DIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHP 604
             E ++P+ D+   W  ME  +  G ARAIGVSNFS KK+E+LL++A V PA NQVE +P
Sbjct: 133 PKEVILPSFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNP 192

Query: 605 VWQQAKLRDLCASKGIHFSAYSPLGSPGT-FKAFSVLEHPVVVSTAEKLGKTPAQVALRW 781
           +WQQ  LR++C  +G+    YSPLG+ GT + + +V++  V+   A   GKT AQ+ LRW
Sbjct: 193 MWQQRTLREVCRREGVQLCGYSPLGAKGTPWGSAAVMDSGVLQEIAGAKGKTLAQICLRW 252

Query: 782 GVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAKLIRGKFWTHPEGVFKS 961
             + G  +L K+ NE+R++ N+D+++W +  +     S++ Q + + G  +    G +KS
Sbjct: 253 LYEQGDVLLVKTYNEKRMKENLDIFNWELTDEERERISQLPQLRGLPGLEFISDHGPYKS 312

Query: 962 EEEIWDGEI 988
            E++WDG++
Sbjct: 313 VEDLWDGDV 321

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>O94735:XYL1_PICGU NADPH-dependent D-xylose reductase - Pichia guilliermondii (Yeast)|
           (Candida guilliermondii)
          Length = 317

 Score =  223 bits (568), Expect = 1e-57
 Identities = 120/300 (40%), Positives = 177/300 (59%), Gaps = 21/300 (7%)
 Frame = +2

Query: 68  LHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKV 247
           +   LN+G ++PSVG G W+ +     D +Y A+K GYR  D A+ YGNEKE+G  + + 
Sbjct: 1   MSITLNSGYEMPSVGFGCWKVDKATCADTIYNAIKVGYRLFDGAEDYGNEKEVGEGINRA 60

Query: 248 FDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRM------ 409
            DEG+  R +LF+ SKLW + H P++V  ALD TL DL+ DY+DL+L+H+PI        
Sbjct: 61  LDEGLVARDELFVVSKLWNSFHDPKNVEKALDRTLSDLKVDYLDLFLIHFPIAFKFVPFE 120

Query: 410 -KKGAGF---NPENVIPADIPA--TWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARV 571
            K   GF   + +  I   +P   TW A+E + + GK R+IG+SNF    +++LL  A++
Sbjct: 121 EKYPPGFYCGDGDKFIYEGVPIIDTWRALEKMVEKGKIRSIGISNFPGALIQDLLRGAKI 180

Query: 572 TPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS---------VLEHPV 724
            PA  Q+E HP  QQ +L +   S+GI  +AYS  G P +F   +         + EH V
Sbjct: 181 KPAVLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFG-PQSFVELNHPRVKDVKPLFEHDV 239

Query: 725 VVSTAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIE 904
           + S AEK  KTPAQV LRW  Q G +V+PKS N +R+ +N+ V D+ +  + F   S+++
Sbjct: 240 IKSVAEKANKTPAQVLLRWATQRGLAVIPKSNNPDRLLSNLKVNDFDLSQEDFKEISKLD 299

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>Q7G765:NADO2_ORYSJ Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp.|
           japonica (Rice)
          Length = 322

 Score =  219 bits (559), Expect = 1e-56
 Identities = 125/307 (40%), Positives = 185/307 (60%), Gaps = 12/307 (3%)
 Frame = +2

Query: 98  IPSVGLGT-----WQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG- 259
           +P +G+GT       SE      A+  A++ GYRH D A++Y  E  +  A+ +    G 
Sbjct: 18  MPRIGMGTAAFPFTSSEETTA--ALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGL 75

Query: 260 VTTRKDLFITSKLWCTN-HAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA---GF 427
           V +R D+F+TSKLWC++ HA   VP A + TL++L  DYVDL LVHWP  +  G+    F
Sbjct: 76  VASRADVFVTSKLWCSDLHAGRVVPAARE-TLRNLGMDYVDLLLVHWPATVAPGSYDFPF 134

Query: 428 NPENVIPA-DIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHP 604
             E + PA D+   W  ME  +  G ARAIGVSNFS KK+E+LL+ A V PAANQVE +P
Sbjct: 135 PKEEMAPAFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNP 194

Query: 605 VWQQAKLRDLCASKGIHFSAYSPLGSPGT-FKAFSVLEHPVVVSTAEKLGKTPAQVALRW 781
           +WQQ  LR++C  +G+    YSPLG+ GT + + +V++  V+   A+  GKT AQ+ LRW
Sbjct: 195 MWQQRTLREVCRREGVQLCGYSPLGAKGTPWGSAAVMDSGVLHDIAQTKGKTLAQICLRW 254

Query: 782 GVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAKLIRGKFWTHPEGVFKS 961
             + G  +L K+ NE R++ N+D++DW +  +     S++ Q + + G  +    G +K 
Sbjct: 255 MYEQGDVLLVKTYNENRMKENLDIFDWELTEEERDKISKLPQQRGLTGMQFVCDNGPYKC 314

Query: 962 EEEIWDG 982
            E++WDG
Sbjct: 315 VEDLWDG 321

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>P26690:6DCS_SOYBN NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean)|
          Length = 315

 Score =  219 bits (559), Expect = 1e-56
 Identities = 122/306 (39%), Positives = 182/306 (59%), Gaps = 8/306 (2%)
 Frame = +2

Query: 95  KIPSVGLGTWQSEPGVV-----GDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           ++P VG+G   S P         +A+  AVK GYRH D A  YG+E+ +G ALK+    G
Sbjct: 20  RMPVVGMG---SAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLG 76

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP-- 433
           + +R+DLF+TSKLW T + P  V  AL  +L+ LQ +Y+DLYL+HWP+  + G    P  
Sbjct: 77  LVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIE 136

Query: 434 -ENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVW 610
            E+++P D+   W +ME     G  +AIGVSNFS KK++ LL+VA + P  +QVE +  W
Sbjct: 137 VEDLLPFDVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAW 196

Query: 611 QQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQ 790
           QQ KLR+ C   GI  +A+SPL    +     V+E+ V+   AE  GK+ AQV+LRW  +
Sbjct: 197 QQKKLREFCKENGIIVTAFSPLRKGASRGPNEVMENDVLKEIAEAHGKSIAQVSLRWLYE 256

Query: 791 AGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAKLIRGKFWTHPEGVFKSEEE 970
            G + +PKS ++ER+  N+ ++DW++        S+I Q++LI G   T P+       +
Sbjct: 257 QGVTFVPKSYDKERMNQNLHIFDWALTEQDHHKISQISQSRLISGP--TKPQ-----LAD 309

Query: 971 IWDGEI 988
           +WD +I
Sbjct: 310 LWDDQI 315

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>P21300:ALD1_MOUSE Aldose reductase-related protein 1 - Mus musculus (Mouse)|
          Length = 316

 Score =  219 bits (557), Expect = 2e-56
 Identities = 126/281 (44%), Positives = 162/281 (57%), Gaps = 12/281 (4%)
 Frame = +2

Query: 62  MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           MA    L+T AK+P VGLGTW+S PG V +AV AA+ AGYRHIDCA VY NE E+G A++
Sbjct: 1   MATFVELSTKAKMPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQ 60

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 421
           +   E    R+DLFI SKLW T      V  A   TL DL+ DY+DLYLVHWP   + G 
Sbjct: 61  EKIKENAVKREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGN 120

Query: 422 GFNPEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTP 577
              P++      +  +     W AME L D G  +A+G+SNF+  ++E LL     +  P
Sbjct: 121 ALLPKDNKGKVLLSKSTFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKP 180

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS----VLEHPVVVSTAEK 745
             NQ+E HP   Q KL   C SKGI  +AYSPLGSP    A      V+E P +   A K
Sbjct: 181 VTNQIESHPYLTQEKLIQYCQSKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAK 240

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI 868
             KT AQV +R+ VQ    V+PKS    RI+ N+ V+D+ +
Sbjct: 241 HKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENLQVFDFQL 281

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>P45377:ALD2_MOUSE Aldose reductase-related protein 2 - Mus musculus (Mouse)|
          Length = 316

 Score =  217 bits (553), Expect = 7e-56
 Identities = 126/287 (43%), Positives = 163/287 (56%), Gaps = 12/287 (4%)
 Frame = +2

Query: 62  MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           MA    L+T AK+P VGLGTW+S P  V +AV AA+ AGYRHIDCA  Y NE E+G A++
Sbjct: 1   MATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQ 60

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 421
           +   E    R+DLFI SKLW T    + +  A   TL DL+ DY+DLYL+HWP  ++ G 
Sbjct: 61  EKIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGK 120

Query: 422 GFNPEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTP 577
              P++               W  ME L D G  +A+GVSNF+  ++E LL     +  P
Sbjct: 121 ELFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKP 180

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF----SVLEHPVVVSTAEK 745
             NQVECHP   Q KL   C SKGI  +AYSPLGSP    A     S+LE P +   A K
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAK 240

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFA 886
             KT AQV +R+ +Q    V+PKS    RI+ NI V+D+ +  +  A
Sbjct: 241 HEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMA 287

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>O08782:ALD2_CRIGR Aldose reductase-related protein 2 - Cricetulus griseus (Chinese|
           hamster)
          Length = 316

 Score =  217 bits (553), Expect = 7e-56
 Identities = 138/323 (42%), Positives = 180/323 (55%), Gaps = 15/323 (4%)
 Frame = +2

Query: 62  MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           M+    L+T AK+P VGLGTWQS PG V +AV  A+ AGYRHIDCA  Y NE E+G A++
Sbjct: 1   MSTFVELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQ 60

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 421
           +   E    R+DLFI SKLW T    + +  A   TL DL+ DY+DLYL+HWP  ++ G 
Sbjct: 61  EKIKEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGK 120

Query: 422 GFNPE----NVIPADIP--ATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTP 577
              P+    NV+ + I     W  ME L D G  +A+GVSNF+  ++E +L     +  P
Sbjct: 121 ELFPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKP 180

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF----SVLEHPVVVSTAEK 745
             NQVECHP   Q KL + C SKGI  +AYSPLGSP    A     S+LE P +   A K
Sbjct: 181 VTNQVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFA---GFSEIEQAKL 916
             KT AQV +R+ +Q    V+PKS    RI  N  V+D+ +     A   GF+   +A L
Sbjct: 241 HKKTSAQVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMATILGFNRNWRACL 300

Query: 917 IRGKFWTHPEGVFKSEEEIWDGE 985
           +       PE V   EE  +D E
Sbjct: 301 L-------PETV-NMEEYPYDAE 315

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>P14065:GCY_YEAST Protein GCY - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 312

 Score =  217 bits (552), Expect = 9e-56
 Identities = 123/278 (44%), Positives = 167/278 (60%), Gaps = 16/278 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LNTGA+IP +GLGTWQS+      AV  A+K GYRHID A +Y NE ++G A+K   D G
Sbjct: 14  LNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK---DSG 70

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRM---------- 409
           V  R+++F+T+KLWCT H   +  VALD +L+ L  DYVDLYL+HWP R+          
Sbjct: 71  V-PREEIFVTTKLWCTQH--HEPEVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDI 127

Query: 410 ----KKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVA--RV 571
                K  G    ++   +   TW  M+ L  +GK +A+GVSNFS   +++LLA    ++
Sbjct: 128 LSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKL 187

Query: 572 TPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLG 751
           TPAANQVE HP+  Q +L + C SKGI   AYSPLGS        +L+ PV++  A+K  
Sbjct: 188 TPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDA----PLLKEPVILEIAKKNN 243

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWS 865
             P  V + W VQ G+ VLPKS N +RI+ N  ++  S
Sbjct: 244 VQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIFTLS 281

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>O60218:AK1BA_HUMAN Aldo-keto reductase family 1 member B10 - Homo sapiens (Human)|
          Length = 316

 Score =  216 bits (551), Expect = 1e-55
 Identities = 131/287 (45%), Positives = 165/287 (57%), Gaps = 12/287 (4%)
 Frame = +2

Query: 62  MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           MA    L+T AK+P VGLGTW+S  G V +AV  A+ AGYRHIDCA VY NE E+G A++
Sbjct: 1   MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 421
           +   E    R+DLFI SKLW T      V  A + TL+DL+  Y+D+YL+HWP   K G 
Sbjct: 61  EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120

Query: 422 GFNPE----NVI--PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTP 577
              P+    N I   A     W AME L D G  +A+GVSNFS  ++E+LL     +  P
Sbjct: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF----SVLEHPVVVSTAEK 745
             NQVECHP   Q KL   C SKGI  +AYSPLGSP    A     S+LE P +   A K
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFA 886
             KT AQV +R+ +Q    V+PKS    RI  NI V+D+ +  +  A
Sbjct: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287

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>Q9P430:XYL1_CANSH NAD(P)H-dependent D-xylose reductase - Candida shehatae (Yeast)|
          Length = 323

 Score =  214 bits (545), Expect = 6e-55
 Identities = 121/298 (40%), Positives = 172/298 (57%), Gaps = 21/298 (7%)
 Frame = +2

Query: 74  FVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFD 253
           F LN G ++PS+G G W+ +     D VY A+KAGYR  D A+ YGNE+E+G  +K+  D
Sbjct: 9   FKLNNGLEMPSIGFGCWKLDKSTAADQVYNAIKAGYRLFDGAEDYGNEQEVGEGVKRAID 68

Query: 254 EGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRM-------K 412
           EG+ TR+++F+TSKLW   H P++V  AL+ TL+DL+ DYVDL+L+H+PI         K
Sbjct: 69  EGIVTREEIFLTSKLWNNYHDPKNVETALNKTLKDLKVDYVDLFLIHFPIAFKFVPIEEK 128

Query: 413 KGAGF---NPENVIPADIP--ATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTP 577
              GF   + +N +  D+P   TW A+E L  +GK R+IGVSNF    + +L   A + P
Sbjct: 129 YPPGFYCGDGDNFVYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLFRGATIKP 188

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF---------SVLEHPVVV 730
           A  QVE HP  QQ KL +     GI  +AYS  G P +F            ++ EH V+ 
Sbjct: 189 AVLQVEHHPYLQQPKLIEYAQKVGITVTAYSSFG-PQSFVEMNQGRALNTPTLFEHDVIK 247

Query: 731 STAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIE 904
           + A K  K PA+V LRW  Q G +V+PKS   ER+  N    D+ +  + F   S+++
Sbjct: 248 AIAAKHNKVPAEVLLRWSAQRGIAVIPKSNLPERLVQNRSFNDFELTKEDFEEISKLD 305

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>P70694:DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 - Mus musculus (Mouse)|
          Length = 323

 Score =  213 bits (543), Expect = 1e-54
 Identities = 125/313 (39%), Positives = 183/313 (58%), Gaps = 18/313 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEP---GVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           L+ G  IP +G GT+  +        +A   A+ AG+RHID A +Y NEKE+G A++   
Sbjct: 10  LSDGHFIPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F TSK+WCT H PE V V L+ +L+ LQ DYVDLYL+H+P+ MK G  + 
Sbjct: 70  ADGTVKREDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKPGENYL 129

Query: 431 PEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAV--ARVTPAAN 586
           P++          DI  TW AME   D+G A++IGVSNF+ +++E++L     +  P  N
Sbjct: 130 PKDENGKLIYDAVDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCN 189

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS-----VLEHPVVVSTAEKLG 751
           QVECHP   Q KL D C SK I   AYS LGS    +        +L++PV+ S A+K  
Sbjct: 190 QVECHPYLNQGKLLDFCRSKDIVLVAYSALGSHREKQWVDQSSPVLLDNPVLGSMAKKYN 249

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEI-EQAKLIRG- 925
           +TPA +ALR+ +Q G  VL KS +E+RI+ N+ V+++ +  +      ++ +  + I G 
Sbjct: 250 RTPALIALRYQLQRGVVVLAKSFSEKRIKENMQVFEFQLTSEDMKVLDDLNKNIRYISGS 309

Query: 926 KFWTHPEGVFKSE 964
            F  HP+  F  E
Sbjct: 310 SFKDHPDFPFWDE 322

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>Q5REQ0:AK1C1_PONPY Aldo-keto reductase family 1 member C1 homolog - Pongo pygmaeus|
           (Orangutan)
          Length = 323

 Score =  211 bits (537), Expect = 5e-54
 Identities = 123/287 (42%), Positives = 172/287 (59%), Gaps = 21/287 (7%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN    +P +G GT+         A+ A   A++AG+RHID A +Y NE+++G A++   
Sbjct: 10  LNDSHFMPVLGFGTYAPPEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F TSKLWC +H PE V  AL+ +L++LQ DYVDLYLVH+P+ +K G    
Sbjct: 70  ADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLVHFPVSVKPG---- 125

Query: 431 PENVIP-----------ADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARV 571
            E VIP            D+ ATW AME   D+G A++IGVSNF+ +++E +L     + 
Sbjct: 126 -EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184

Query: 572 TPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS-----VLEHPVVVST 736
            P  NQVECHP + Q KL D C SK I   AYS LGS    K        +LE PV+ + 
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEKWVDPNSPVLLEDPVLCAL 244

Query: 737 AEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           A+K  +TPA +ALR+ +Q G  VL KS NE+RIR N+ V+D+ +  +
Sbjct: 245 AKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRQNMQVFDFQLTSE 291

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>P80508:PE2R_RABIT Prostaglandin-E(2) 9-reductase - Oryctolagus cuniculus (Rabbit)|
          Length = 323

 Score =  210 bits (534), Expect = 1e-53
 Identities = 121/282 (42%), Positives = 169/282 (59%), Gaps = 16/282 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           L+ G  IP +G GT+  E      A+ A   A+ AG+RHID A  Y NEKE+G A++   
Sbjct: 10  LSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F TSKLWCT H PE V  +L+ +L++LQ DYVDLY++H+P  +K G    
Sbjct: 70  ADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGVEII 129

Query: 431 PEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P +          DI ATW AME   D+G A++IGVSNF+ +++E +L     +  P  N
Sbjct: 130 PTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPG-----TFKAFSVLEHPVVVSTAEKLG 751
           QVECHP   Q KL + C SKGI   AYS LGS          A  +LE P++ + A+K  
Sbjct: 190 QVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAKKHQ 249

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           +TPA +ALR+ +Q G  VL KS  E+RI+ NI V+++ +P +
Sbjct: 250 QTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSE 291

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>Q95JH6:AK1C1_MACFU Aldo-keto reductase family 1 member C1 homolog - Macaca fuscata|
           fuscata (Japanese macaque)
          Length = 323

 Score =  209 bits (533), Expect = 1e-53
 Identities = 120/282 (42%), Positives = 171/282 (60%), Gaps = 16/282 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  +P +G GT+         A+ A   A++AG+RHID A +Y NE+ +G A++   
Sbjct: 10  LNDGHFMPVLGFGTYAPAEVPKNKAIEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F TSKLWC +H PE V  AL+ +L++LQ DYVDLYL+H+P+ +K G    
Sbjct: 70  ADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLKPGEELI 129

Query: 431 PEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P++          D+ ATW AME   D+G A++IGVSNF+ +++E +L     +  P  N
Sbjct: 130 PKDENGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGS----PGTFKAFSV-LEHPVVVSTAEKLG 751
           QVECHP   Q KL D C SK I   AYS LGS    P   +   V LE PV+ + A+K  
Sbjct: 190 QVECHPYLNQRKLLDFCKSKDIVLVAYSALGSHREKPWVDQNSPVLLEDPVLCALAKKHK 249

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           +TPA +ALR+ +Q G  VL KS NE+RIR N+ V+++ +  +
Sbjct: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRENMKVFEFQLTSE 291

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>P87039:XYL2_CANTR NADPH-dependent D-xylose reductase II,III - Candida tropicalis|
           (Yeast)
          Length = 324

 Score =  209 bits (532), Expect = 2e-53
 Identities = 115/289 (39%), Positives = 161/289 (55%), Gaps = 23/289 (7%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LN+G ++P VG G W+       D +Y A+K GYR  D A+ YGNEKE+G  + +   EG
Sbjct: 12  LNSGYEMPLVGFGCWKVNNETAADQIYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEG 71

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK--------- 412
           +  R++LFITSKLW   H P++V  AL+ TL DL  DYVDL+L+H+PI  K         
Sbjct: 72  LVKREELFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFKFVPIEEKYP 131

Query: 413 ------KGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVT 574
                  G  F+ E+V   D   TW A+E L ++GK ++IG+SNF+   + +L+  A + 
Sbjct: 132 PGFYCGDGDNFHYEDVPLLD---TWKALEKLVEAGKIKSIGISNFTGALIYDLIRGATIK 188

Query: 575 PAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLG--------SPGTFKAFSVLEHPVVV 730
           PA  Q+E HP  QQ KL +     GI  + YS  G        S       ++ EH  + 
Sbjct: 189 PAVLQIEHHPYLQQPKLIEYVQKAGIAITGYSSFGPQSFLELESKRALNTPTLFEHETIK 248

Query: 731 STAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           S A+K GK+PAQV LRW  Q   +V+PKS N ER+  N+ V D+ +  D
Sbjct: 249 SIADKHGKSPAQVLLRWATQRNIAVIPKSNNPERLAQNLSVVDFDLTKD 297

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>Q04828:AK1C1_HUMAN Aldo-keto reductase family 1 member C1 - Homo sapiens (Human)|
          Length = 323

 Score =  209 bits (532), Expect = 2e-53
 Identities = 122/287 (42%), Positives = 173/287 (60%), Gaps = 21/287 (7%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  +P +G GT+         A+ A   A++AG+RHID A +Y NE+++G A++   
Sbjct: 10  LNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F TSKLWC +H PE V  AL+ +L++LQ DYVDLYL+H+P+ +K G    
Sbjct: 70  ADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG---- 125

Query: 431 PENVIP-----------ADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARV 571
            E VIP            D+ ATW A+E   D+G A++IGVSNF+ +++E +L     + 
Sbjct: 126 -EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184

Query: 572 TPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGS----PGTFKAFSV-LEHPVVVST 736
            P  NQVECHP + Q KL D C SK I   AYS LGS    P       V LE PV+ + 
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244

Query: 737 AEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           A+K  +TPA +ALR+ +Q G  VL KS NE+RIR N+ V+++ +  +
Sbjct: 245 AKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSE 291

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>P78736:XYL1_PACTA NAD(P)H-dependent D-xylose reductase - Pachysolen tannophilus|
           (Yeast)
          Length = 318

 Score =  207 bits (528), Expect = 5e-53
 Identities = 121/299 (40%), Positives = 170/299 (56%), Gaps = 20/299 (6%)
 Frame = +2

Query: 71  HFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           ++ LN G KIP++G+G W+ E     D VYAA+K GYR  DCA  YGNEKE+G  + +  
Sbjct: 5   YYTLNNGRKIPAIGMGCWKLENAA--DMVYAAIKEGYRLFDCACDYGNEKEVGEGINRAI 62

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRM------- 409
            +G+  RKDLFITSKLW   HA E+V  AL  +L D   DY DLYL+H+PI         
Sbjct: 63  KDGLVKRKDLFITSKLWNNFHAKENVKKALMKSLSDFNLDYFDLYLMHFPISFKFVPFEE 122

Query: 410 KKGAGF---NPENVIPADIP--ATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVT 574
           K   GF   + +  I  D+P   TW AME+L D G  ++IGVSN S   +E+L+  AR+ 
Sbjct: 123 KYPPGFYCGDGDKFIYEDVPIIETWRAMENLVDEGLVKSIGVSNVSGGLLEDLIKAARIK 182

Query: 575 PAANQVECHPVWQQAKLRDLCASKGIHFSAYS--------PLGSPGTFKAFSVLEHPVVV 730
           PA+ Q+E HP  QQ KL +    KGI  + YS         LG+    K   + E+  + 
Sbjct: 183 PASLQIEHHPYLQQNKLVEYAQLKGIVVTGYSNFGPLSFLELGNETAKKTQPLYENKTIT 242

Query: 731 STAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQ 907
           + A K GKTP QV LRW  Q G +++PKST    +  N+ V ++ +  + F   +++++
Sbjct: 243 TIAAKHGKTPFQVLLRWVNQRGIAIIPKSTFPNTLAVNLHVDEFDLTKEDFEEIAKLDR 301

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>P31867:XYL1_PICST NAD(P)H-dependent D-xylose reductase - Pichia stipitis (Yeast)|
          Length = 318

 Score =  207 bits (527), Expect = 7e-53
 Identities = 118/299 (39%), Positives = 169/299 (56%), Gaps = 24/299 (8%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LN+G  +P+VG G W+ +     + +Y A+K GYR  D A+ Y NEK +G  +KK  DEG
Sbjct: 6   LNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAIDEG 65

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK--------- 412
           +  R+DLF+TSKLW   H P++V  AL+ TL DLQ DYVDL+L+H+P+  K         
Sbjct: 66  IVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLEEKYP 125

Query: 413 ------KGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVT 574
                 KG  F+ E+V    I  TW A+E L  +GK R+IGVSNF    + +LL  A + 
Sbjct: 126 PGFYCGKGDNFDYEDV---PILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLRGATIK 182

Query: 575 PAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS---------VLEHPVV 727
           P+  QVE HP  QQ +L +   S+GI  +AYS  G P +F   +         + E+  +
Sbjct: 183 PSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFG-PQSFVELNQGRALNTSPLFENETI 241

Query: 728 VSTAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIE 904
            + A K GK+PAQV LRW  Q G +++PKS    R+  N DV  + +    FA  ++++
Sbjct: 242 KAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKLD 300

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>O13283:XYL1_CANTR NAD(P)H-dependent D-xylose reductase I,II - Candida tropicalis|
           (Yeast)
          Length = 324

 Score =  207 bits (527), Expect = 7e-53
 Identities = 114/289 (39%), Positives = 160/289 (55%), Gaps = 23/289 (7%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LN+G ++P VG G W+       D +Y A+K GYR  D A+ YGNEKE+G  + +   EG
Sbjct: 12  LNSGYEMPLVGFGCWKVTNATAADQIYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEG 71

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK--------- 412
           +  R++LFITSKLW   H P++V  AL+ TL DL  DYVDL+L+H+PI  K         
Sbjct: 72  LVKREELFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFKFVPIEEKYP 131

Query: 413 ------KGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVT 574
                  G  F+ E+V   D   TW A+E L ++GK ++IG+SNF+   + +L+  A + 
Sbjct: 132 PGFYCGDGDNFHYEDVPLLD---TWKALEKLVEAGKIKSIGISNFTGALIYDLIRGATIK 188

Query: 575 PAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLG--------SPGTFKAFSVLEHPVVV 730
           PA  Q+E HP  QQ KL +     GI  + YS  G        S       ++ EH  + 
Sbjct: 189 PAVLQIEHHPYLQQPKLIEYVQKAGIAITGYSSFGPQSFLELESKRALNTPTLFEHETIK 248

Query: 731 STAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
             A+K GK+PAQV LRW  Q   +V+PKS N ER+  N+ V D+ +  D
Sbjct: 249 LIADKHGKSPAQVLLRWATQRNIAVIPKSNNPERLAQNLSVVDFDLTKD 297

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>Q95JH7:AK1C1_MACFA Aldo-keto reductase family 1 member C1 homolog - Macaca|
           fascicularis (Crab eating macaque) (Cynomolgus monkey)
          Length = 323

 Score =  207 bits (527), Expect = 7e-53
 Identities = 119/282 (42%), Positives = 171/282 (60%), Gaps = 16/282 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  +P +G GT+         A+ A   A++AG+RHID A +Y NE+ +G A++   
Sbjct: 10  LNDGHFMPVLGFGTYAPAEVPKNKALEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F TSKLWC +H PE V  AL+ +L++LQ DYVDLYL+H+P+ +K G    
Sbjct: 70  ADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLKPGEELI 129

Query: 431 PEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P++          D+ ATW AME   D+G A++IGVSNF+ +++E +L     +  P  N
Sbjct: 130 PKDENGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGS----PGTFKAFSV-LEHPVVVSTAEKLG 751
           QVECHP   Q KL D C SK I   A+S LGS    P   +   V LE PV+ + A+K  
Sbjct: 190 QVECHPYLNQRKLLDFCKSKDIVLVAFSALGSHREKPWVDQNSPVLLEDPVLCALAKKHK 249

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           +TPA +ALR+ +Q G  VL KS NE+RIR N+ V+++ +  +
Sbjct: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRENMKVFEFQLTSE 291

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>P52895:AK1C2_HUMAN Aldo-keto reductase family 1 member C2 - Homo sapiens (Human)|
          Length = 323

 Score =  206 bits (525), Expect = 1e-52
 Identities = 122/287 (42%), Positives = 171/287 (59%), Gaps = 21/287 (7%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTW---QSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  +P +G GT+   +       +AV  A++AG+ HID A VY NE+++G A++   
Sbjct: 10  LNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F TSKLW  +H PE V  AL+ +L++LQ DYVDLYL+H+P+ +K G    
Sbjct: 70  ADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG---- 125

Query: 431 PENVIP-----------ADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARV 571
            E VIP            D+ ATW AME   D+G A++IGVSNF+ + +E +L     + 
Sbjct: 126 -EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKY 184

Query: 572 TPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGS----PGTFKAFSV-LEHPVVVST 736
            P  NQVECHP + Q KL D C SK I   AYS LGS    P       V LE PV+ + 
Sbjct: 185 KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCAL 244

Query: 737 AEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           A+K  +TPA +ALR+ +Q G  VL KS NE+RIR N+ V+++ +  +
Sbjct: 245 AKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSE 291

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>P17516:AK1C4_HUMAN Aldo-keto reductase family 1 member C4 - Homo sapiens (Human)|
          Length = 323

 Score =  203 bits (517), Expect = 1e-51
 Identities = 118/282 (41%), Positives = 171/282 (60%), Gaps = 16/282 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  +P +G GT+         AV     A++AG+RHID A +Y NE+++G A++   
Sbjct: 10  LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F TSKLWCT   P+ V  AL+ +L+ LQ DYVDLYL+H+P+ +K G    
Sbjct: 70  ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 129

Query: 431 PEN----VI--PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P++    VI    D+ ATW  ME   D+G A++IGVSNF+C+++E +L     +  P  N
Sbjct: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCN 189

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPG-----TFKAFSVLEHPVVVSTAEKLG 751
           QVECHP   Q+KL D C SK I   A+S LG+          +  +LE PV+ + A+K  
Sbjct: 190 QVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHK 249

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           +TPA +ALR+ +Q G  VL KS NE+RIR NI V+++ +  +
Sbjct: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSE 291

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>O74237:XYL1_CANTE NAD(P)H-dependent D-xylose reductase - Candida tenuis (Yeast)|
          Length = 322

 Score =  202 bits (513), Expect = 3e-51
 Identities = 114/276 (41%), Positives = 159/276 (57%), Gaps = 21/276 (7%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           L++G  +PS+G G W+      G+ VY A+KAGYR  D A+ YGNEKE+G  +K+  DEG
Sbjct: 10  LSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGDGVKRAIDEG 69

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRM-------KKG 418
           +  R+++F+TSKLW   H P++V  AL+ TL DL+ DYVDL+L+H+PI         K  
Sbjct: 70  LVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFKFVPIEEKYP 129

Query: 419 AGF---NPENVIPADIP--ATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAA 583
            GF   +  N +  D+P   TW A+E L  +GK ++IGVSNF    + +LL  A + PA 
Sbjct: 130 PGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLLRGATIKPAV 189

Query: 584 NQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF---------SVLEHPVVVST 736
            QVE HP  QQ KL +     G+  +AYS  G P +F            ++  H  + + 
Sbjct: 190 LQVEHHPYLQQPKLIEFAQKAGVTITAYSSFG-PQSFVEMNQGRALNTPTLFAHDTIKAI 248

Query: 737 AEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRAN 844
           A K  KTPA+V LRW  Q G +V+PKS   ER+  N
Sbjct: 249 AAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQN 284

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>P31210:AK1D1_RAT 3-oxo-5-beta-steroid 4-dehydrogenase - Rattus norvegicus (Rat)|
          Length = 326

 Score =  202 bits (513), Expect = 3e-51
 Identities = 123/317 (38%), Positives = 181/317 (57%), Gaps = 19/317 (5%)
 Frame = +2

Query: 71  HFVLNTGAKIPSVGLGTWQSE---PGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           H  LN G  IP +GLGT+      PG    AV  A+  GYRHID A VY NE E+G A++
Sbjct: 9   HIPLNDGNSIPIIGLGTYSDPRPVPGKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIR 68

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 421
           +   EG   R+++F   KLW T+H PE V  AL+ TLQ L+ DY+DLY++  P+  K G 
Sbjct: 69  EKVAEGKVKREEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFKPGE 128

Query: 422 GFNPEN----VI--PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTP 577
            F P++    VI   +++ ATW A+E+  D+G  +++GVSNF+ +++E +L     +  P
Sbjct: 129 EFYPKDENGRVIYHKSNLCATWEALEACKDAGLVKSLGVSNFNRRQLEVILNKPGLKYKP 188

Query: 578 AANQVECHPVWQQAKLRDLCASKGIHF-SAYSPLG---SPGTFKAFS--VLEHPVVVSTA 739
             NQVECHP + Q KL ++ AS    F  AYSPLG   +P      S  +L+  ++ S  
Sbjct: 189 VTNQVECHPYFTQTKLLEVSASSMTSFIVAYSPLGTCRNPLWVNVSSPPLLKDELLTSLG 248

Query: 740 EKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEI-EQAKL 916
           +K  KT AQ+ LR+ +Q G  V+PKST  ERI+ N  ++D+S+  +       + +  + 
Sbjct: 249 KKYNKTQAQIVLRFDIQRGLVVIPKSTTPERIKENFQIFDFSLTKEEMKDIEALNKNVRF 308

Query: 917 IRGKFWT-HPEGVFKSE 964
           +    W+ HPE  F  E
Sbjct: 309 VEMLMWSDHPEYPFHDE 325

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>Q5R7C9:AK1C3_PONPY Aldo-keto reductase family 1 member C3 homolog - Pongo pygmaeus|
           (Orangutan)
          Length = 323

 Score =  201 bits (510), Expect = 7e-51
 Identities = 117/283 (41%), Positives = 171/283 (60%), Gaps = 17/283 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVG----DAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKV 247
           LN G  +P +G GT+ + P V      +    A++AG+RHID A +Y NE+++G A++  
Sbjct: 10  LNDGHFMPVLGFGTY-APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSK 68

Query: 248 FDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGF 427
             +G   R+D+F TSKLW T H PE V  AL+ +L+  Q DYVDLYL+H P+ +K G   
Sbjct: 69  IADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEEL 128

Query: 428 NPEN----VI--PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAA 583
           +P +    VI    D+  TW AME   D+G A++IGVSNF+ +++E +L     +  P  
Sbjct: 129 SPTDENGKVIFDIVDLCTTWEAMEECKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVC 188

Query: 584 NQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS-----VLEHPVVVSTAEKL 748
           NQVECHP + ++KL D C SK I   AYS LGS    +        +LE PV+ + A+K 
Sbjct: 189 NQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKH 248

Query: 749 GKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
            +TPA +ALR+ +Q G  VL KS NE+RIR N+ V+++ +  +
Sbjct: 249 KRTPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTAE 291

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>P42330:AK1C3_HUMAN Aldo-keto reductase family 1 member C3 - Homo sapiens (Human)|
          Length = 323

 Score =  201 bits (510), Expect = 7e-51
 Identities = 117/283 (41%), Positives = 171/283 (60%), Gaps = 17/283 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVG----DAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKV 247
           LN G  +P +G GT+ + P V      +    A++AG+RHID A +Y NE+++G A++  
Sbjct: 10  LNDGHFMPVLGFGTY-APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSK 68

Query: 248 FDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGF 427
             +G   R+D+F TSKLW T H PE V  AL+ +L+  Q DYVDLYL+H P+ +K G   
Sbjct: 69  IADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEEL 128

Query: 428 NPEN----VI--PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAA 583
           +P +    VI    D+  TW AME   D+G A++IGVSNF+ +++E +L     +  P  
Sbjct: 129 SPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVC 188

Query: 584 NQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS-----VLEHPVVVSTAEKL 748
           NQVECHP + ++KL D C SK I   AYS LGS    +        +LE PV+ + A+K 
Sbjct: 189 NQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKH 248

Query: 749 GKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
            +TPA +ALR+ +Q G  VL KS NE+RIR N+ V+++ +  +
Sbjct: 249 KRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAE 291

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>P52898:DDBX_BOVIN Dihydrodiol dehydrogenase 3 - Bos taurus (Bovine)|
          Length = 323

 Score =  200 bits (509), Expect = 9e-51
 Identities = 128/315 (40%), Positives = 185/315 (58%), Gaps = 20/315 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  IP +G GT+        +A+     A++AG+RHID A +Y NE+++G A++   
Sbjct: 10  LNDGHFIPVLGFGTFAPREVPKSEALEVTKFAIEAGFRHIDSAHLYQNEEQVGQAIRSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F TSKLW T+  PE V  AL+ +L +LQ DYVDLY++H+P+ +K G    
Sbjct: 70  ADGTVKREDIFYTSKLWSTSLRPELVRPALEKSLNNLQLDYVDLYIIHFPVALKPGETLF 129

Query: 431 P--ENVIP----ADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P  EN  P     D+  TW A+E   D+G  ++IGVSNF+ K++E++L     +  P  N
Sbjct: 130 PTDENGKPIFDSVDLCRTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCN 189

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS-----VLEHPVVVSTAEKLG 751
           QVECHP + Q+KL D C S  I   AY  LGS    +  +     +LE PV+ + A+K  
Sbjct: 190 QVECHPYFNQSKLLDFCKSHDIVLVAYGALGSQRLKEWVNPNLPFLLEDPVLSAIAKKHR 249

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI-PGDLFA--GF-SEIEQAKLI 919
           +TPA VALR+ +Q G  VL KS N++RI+ NI V+D+ + P D+ A  G  S +   +L+
Sbjct: 250 QTPALVALRYQIQRGVVVLAKSYNKKRIKENIQVFDFELTPEDMKAIDGLNSNMRYNELL 309

Query: 920 RGKFWTHPEGVFKSE 964
            G    HPE  F  E
Sbjct: 310 LGV--GHPEYPFVEE 322

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>P05980:PGFS1_BOVIN Prostaglandin-F synthase 1 - Bos taurus (Bovine)|
          Length = 323

 Score =  200 bits (508), Expect = 1e-50
 Identities = 116/286 (40%), Positives = 174/286 (60%), Gaps = 17/286 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  IP +G GT+  E     +A+ A   A++ G+RH+D A +Y NE+++G A++   
Sbjct: 10  LNDGHFIPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F TSKLWC +  PE V  AL+ +LQ+LQ DYVDLY++H P+ +K G  F 
Sbjct: 70  ADGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLKPGNKFV 129

Query: 431 PEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P++          D+  TW A+E   D+G  ++IGVSNF+ K++E++L     +  P  N
Sbjct: 130 PKDESGKLIFDSVDLCHTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCN 189

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS-----VLEHPVVVSTAEKLG 751
           QVECHP   Q+KL + C S  I   AY+ LG+    +  +     +LE PV+ + A+K  
Sbjct: 190 QVECHPYLNQSKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPVLCAIAKKHK 249

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI-PGDLFA 886
           +TPA VALR+ VQ G  VL KS N++RI+ N+ V+D+ + P D+ A
Sbjct: 250 QTPALVALRYQVQRGVVVLAKSFNKKRIKENMQVFDFELTPEDMKA 295

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>P49378:XYL1_KLULA NAD(P)H-dependent D-xylose reductase - Kluyveromyces lactis (Yeast)|
           (Candida sphaerica)
          Length = 329

 Score =  199 bits (505), Expect = 3e-50
 Identities = 113/287 (39%), Positives = 159/287 (55%), Gaps = 27/287 (9%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LN G K+P VGLG W+    V  D +Y A+K GYR  D AQ Y NEKE+G  + +   EG
Sbjct: 10  LNNGEKMPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEG 69

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK--------- 412
           +  R+DL + SKLW + H P++VP AL+ TL DLQ DYVD++ +H+P+  K         
Sbjct: 70  LVKREDLVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYP 129

Query: 413 ---------KGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVA 565
                    +  G   E  +P  +  TW A+E L D GK +++G+SNFS   +++LL  A
Sbjct: 130 PGFYTGKEDEAKGHIEEEQVP--LLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGA 187

Query: 566 RVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTF------KAF---SVLEH 718
           R+ P A Q+E HP   Q +L     + GI   AYS  G P +F      KA    ++ EH
Sbjct: 188 RIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFG-PVSFLELENKKALNTPTLFEH 246

Query: 719 PVVVSTAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYD 859
             + S A K   TP QV LRW  Q G +++PKS+ +ER+  N+ + D
Sbjct: 247 DTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRIND 293

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>P52897:PGFS2_BOVIN Prostaglandin-F synthase 2 - Bos taurus (Bovine)|
          Length = 323

 Score =  198 bits (504), Expect = 3e-50
 Identities = 115/285 (40%), Positives = 173/285 (60%), Gaps = 17/285 (5%)
 Frame = +2

Query: 83  NTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFD 253
           N G  IP +G GT+  E     +A+ A   A++ G+RH+D A +Y NE+++G A++    
Sbjct: 11  NDGHFIPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKIA 70

Query: 254 EGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 433
           +G   R+D+F TSKLWC +  PE V  AL+ +LQ+LQ DYVDLY++H P+ +K G  F P
Sbjct: 71  DGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLKPGNKFVP 130

Query: 434 EN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAANQ 589
           ++          D+  TW A+E   D+G  ++IGVSNF+ K++E++L     +  P  NQ
Sbjct: 131 KDESGKLIFDSVDLCHTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQ 190

Query: 590 VECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS-----VLEHPVVVSTAEKLGK 754
           VECHP   Q+KL + C S  I   AY+ LG+    +  +     +LE PV+ + A+K  +
Sbjct: 191 VECHPYLNQSKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPVLCAIAKKHKQ 250

Query: 755 TPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI-PGDLFA 886
           TPA VALR+ VQ G  VL KS N++RI+ N+ V+D+ + P D+ A
Sbjct: 251 TPALVALRYQVQRGVVVLAKSFNKKRIKENMQVFDFELTPEDMKA 295

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>Q95JH5:AK1C4_MACFA Aldo-keto reductase family 1 member C4 - Macaca fascicularis (Crab|
           eating macaque) (Cynomolgus monkey)
          Length = 323

 Score =  198 bits (504), Expect = 3e-50
 Identities = 114/283 (40%), Positives = 172/283 (60%), Gaps = 17/283 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGV----VGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKV 247
           LN G  +P +G GT+ + P V    V +    A++AG+RHID A +Y NE+++G A++  
Sbjct: 10  LNDGHFMPVLGFGTY-APPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSK 68

Query: 248 FDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGF 427
             +G   R+D+F TSKLWCT   P+ V  AL+ +L+ LQ DYVDLYL+H+P+ +K G   
Sbjct: 69  IADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGETP 128

Query: 428 NPEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAA 583
            P++          D+ A W AME   D+G A++IGVSNF+ +++E +L     +  P  
Sbjct: 129 LPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNPGLKYKPVC 188

Query: 584 NQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPG-----TFKAFSVLEHPVVVSTAEKL 748
           NQVECHP   Q+KL D C SK I   A+S LG+          + ++LE PV+ + A+K 
Sbjct: 189 NQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPVLCALAKKH 248

Query: 749 GKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
            ++PA +ALR+ +Q G  VL KS NE+RIR N+ V+++ +  +
Sbjct: 249 KRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSE 291

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>Q6Y0Z3:XYL1_CANPA NADH-dependent D-xylose reductase - Candida parapsilosis (Yeast)|
          Length = 324

 Score =  197 bits (501), Expect = 7e-50
 Identities = 114/299 (38%), Positives = 165/299 (55%), Gaps = 24/299 (8%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LN+G +IP VG G W+    V  D +Y A+K+GYR  D A+ Y NE+E+G  +K+   EG
Sbjct: 12  LNSGYEIPLVGFGCWKLTNDVASDQIYRAIKSGYRLFDGAEDYANEQEVGEGIKRAIKEG 71

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK--------- 412
           +  R++LFITSKLW + H  ++V VAL  TL DL  DYVDL+ +H+PI  K         
Sbjct: 72  IVKREELFITSKLWNSFHDKKNVEVALMKTLSDLNLDYVDLFYIHFPIAQKPVPIEKKYP 131

Query: 413 ------KGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVT 574
                  G  ++ E V   D   TW A+E L D G A++IG+SNFS + + +L+    + 
Sbjct: 132 PGFYCGDGDKWSIEEVPLLD---TWRALEKLVDQGLAKSIGISNFSAQLIYDLIRGCTIK 188

Query: 575 PAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS---------VLEHPVV 727
           P A Q+E HP   Q KL +      I  + YS  G P +F             +LE P V
Sbjct: 189 PVALQIEHHPYLTQPKLVEYVQLHDIQITGYSSFG-PQSFLEMDLKRALDTPVLLEEPTV 247

Query: 728 VSTAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIE 904
            S A+K GK+PAQV LR+  Q G +V+P+S + +R+  N+ V D+ +  D     +E++
Sbjct: 248 KSIADKHGKSPAQVLLRYQTQRGIAVIPRSNSPDRMAQNLSVIDFELTQDDLQAIAELD 306

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>Q9P8R5:XYL1_ASPNG NAD(P)H-dependent D-xylose reductase - Aspergillus niger|
          Length = 319

 Score =  197 bits (501), Expect = 7e-50
 Identities = 117/296 (39%), Positives = 160/296 (54%), Gaps = 20/296 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LN+G  +P VG G W+       D +Y A+K GYR  D A  YGNE E G  + +   +G
Sbjct: 8   LNSGYDMPLVGFGLWKVNNDTCADQIYHAIKEGYRLFDGACDYGNEVEAGQGIARAIKDG 67

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK-------KG 418
           +  R++LFI SKLW + H  + V       L D   DY DLY+VH+PI +K         
Sbjct: 68  LVKREELFIVSKLWNSFHDGDRVEPICRKQLADWGIDYFDLYIVHFPISLKYVDPAVRYP 127

Query: 419 AGFNPE----NVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAAN 586
            G+  E        A I  TW AMESL D   AR+IG+SNFS + V +LL  AR+ PA  
Sbjct: 128 PGWKSEKDELEFGNATIQETWTAMESLVDKKLARSIGISNFSAQLVMDLLRYARIRPATL 187

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSV---------LEHPVVVSTA 739
           Q+E HP   Q +L +    +G+  +AYS  G P +F   SV          EH +V S A
Sbjct: 188 QIEHHPYLTQTRLVEYAQKEGLTVTAYSSFG-PLSFLELSVQNAVDSPPLFEHQLVKSIA 246

Query: 740 EKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQ 907
           EK G+TPAQV LRW  Q G +V+PKS N +R++ N+DV  W++  +     S +++
Sbjct: 247 EKHGRTPAQVLLRWATQRGIAVIPKSNNPQRLKQNLDVTGWNLEEEEIKAISGLDR 302

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>O70473:AK1A1_CRIGR Alcohol dehydrogenase [NADP+] - Cricetulus griseus (Chinese|
           hamster)
          Length = 228

 Score =  197 bits (501), Expect = 7e-50
 Identities = 109/229 (47%), Positives = 148/229 (64%), Gaps = 13/229 (5%)
 Frame = +2

Query: 107 VGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG-VTTRKDLF 283
           +GLGTW+S PG V  A+  A+  GYRHIDCA VYGNE EIG ALK+    G    R++LF
Sbjct: 2   IGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELF 61

Query: 284 ITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPEN---VIPAD 454
           +TSKLW T H PEDV  AL  TL DLQ +Y+DLYL+HWP   ++G    P+N    I  D
Sbjct: 62  VTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNDDGTIRYD 121

Query: 455 ---IPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQAKL 625
                 TW A+E+L   G  +A+G+SNF+ ++++++L+VA V PA  QVECHP   Q +L
Sbjct: 122 STHYKETWKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNEL 181

Query: 626 RDLCASKGIHFSAYSPLGSPGTFKAFS------VLEHPVVVSTAEKLGK 754
              C ++G+  +AYSPLGS  + +A+       +LE PVV++ AEK G+
Sbjct: 182 IAHCQARGLEVTAYSPLGS--SDRAWRHPDEPVLLEEPVVLALAEKHGR 228

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>Q12458:YPR1_YEAST Putative reductase 1 - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 312

 Score =  197 bits (500), Expect = 1e-49
 Identities = 121/293 (41%), Positives = 166/293 (56%), Gaps = 17/293 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LNTGA IP +G GTW+S       +V AA+KAGYRHID A +Y NE+E+G A+K   D G
Sbjct: 14  LNTGASIPVLGFGTWRSVDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIK---DSG 70

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPEN 439
           V  R+++FIT+KLW T     D   AL+ +L+ L  DYVDLYL+HWP+ +K        N
Sbjct: 71  V-PREEIFITTKLWGTEQ--RDPEAALNKSLKRLGLDYVDLYLMHWPVPLKTDR-VTDGN 126

Query: 440 VI--------PADIPA-------TWAAMESLYDSGKARAIGVSNFSCKKVEELLAVA--R 568
           V+          DI         TW  M+ L  +GK +A+GVSNFS   ++ELL     +
Sbjct: 127 VLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNK 186

Query: 569 VTPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKL 748
           V PA NQ+E HP+  Q +L   C  KGI   AYSP GS        +L+   ++  A+K 
Sbjct: 187 VVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFGSANA----PLLKEQAIIDMAKKH 242

Query: 749 GKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQ 907
           G  PAQ+ + W +Q G+ VL KS N ERI +N  ++  ++P D F   S + +
Sbjct: 243 GVEPAQLIISWSIQRGYVVLAKSVNPERIVSNFKIF--TLPEDDFKTISNLSK 293

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>P22045:P100_LEIMA Probable reductase - Leishmania major|
          Length = 284

 Score =  197 bits (500), Expect = 1e-49
 Identities = 114/268 (42%), Positives = 151/268 (56%), Gaps = 5/268 (1%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPG-VVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDE 256
           L+ G K+P  GLG WQS  G V  +AV  A+ AGYRHID A +Y NE+ +G  L+     
Sbjct: 11  LSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGLRA---S 67

Query: 257 GVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP----IRMKKGAG 424
           GV  R+D+FIT+KLW T    E    A + + Q L  DY+DLYL+HWP    I  K+G  
Sbjct: 68  GVP-REDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGKDILSKEGKK 126

Query: 425 FNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHP 604
           +            +W A E LY   K RAIGVSNF    +E++LA+  VTP  NQVE HP
Sbjct: 127 YLD----------SWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHP 176

Query: 605 VWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWG 784
           +  QA LR  C +K I   A+SPLG         +L +P++ +   K  KT AQV LRW 
Sbjct: 177 LNNQADLRAFCDAKQIKVEAWSPLGQG------KLLSNPILSAIGAKYNKTAAQVILRWN 230

Query: 785 VQAGHSVLPKSTNEERIRANIDVYDWSI 868
           +Q     +PKS + ERI  N D++D+ +
Sbjct: 231 IQKNLITIPKSVHRERIEENADIFDFEL 258

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>P51652:AKC1H_RAT Aldo-keto reductase family 1 member C18 - Rattus norvegicus (Rat)|
          Length = 323

 Score =  197 bits (500), Expect = 1e-49
 Identities = 111/282 (39%), Positives = 168/282 (59%), Gaps = 16/282 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  IP +G GT+ +E  +   ++ +   A+  G+RHIDC+ +Y NE+EIG A+    
Sbjct: 10  LNDGHSIPVLGFGTYATEENLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
           ++G   R+D+F TSKLW T+H PE V  +L+ +L+ L  DYVDLYL+H+P+ +K G    
Sbjct: 70  EDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGDELL 129

Query: 431 PE----NVI--PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P+    N+I    D+  TW AME   D+G A++IGVSNF+ +++E++L     +  P  N
Sbjct: 130 PQDEHGNLILDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCN 189

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS-----VLEHPVVVSTAEKLG 751
           QVECH    Q+KL   C    I   AY  LG+       +     +L+ P++ + A+K  
Sbjct: 190 QVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPILCTMAKKYK 249

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           +TPA +ALR+ ++ G   L KS NEERIR N+ V+D+ +  D
Sbjct: 250 RTPALIALRYQLERGIVTLVKSFNEERIRENLQVFDFQLASD 291

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>Q95JH4:AK1C4_MACFU Aldo-keto reductase family 1 member C4 - Macaca fuscata fuscata|
           (Japanese macaque)
          Length = 323

 Score =  197 bits (500), Expect = 1e-49
 Identities = 113/283 (39%), Positives = 172/283 (60%), Gaps = 17/283 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGV----VGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKV 247
           LN G  +P +G G++ + P V    V +    A++AG+RHID A +Y NE+++G A++  
Sbjct: 10  LNDGHFMPVLGFGSY-APPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSK 68

Query: 248 FDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGF 427
             +G   R+D+F TSKLWCT   P+ V  AL+ +L+ LQ DYVDLYL+H+P+ +K G   
Sbjct: 69  IADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGETP 128

Query: 428 NPEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAA 583
            P++          D+ A W AME   D+G A++IGVSNF+ +++E +L     +  P  
Sbjct: 129 LPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNPGLKYKPVC 188

Query: 584 NQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPG-----TFKAFSVLEHPVVVSTAEKL 748
           NQVECHP   Q+KL D C SK I   A+S LG+          + ++LE PV+ + A+K 
Sbjct: 189 NQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPVLCALAKKH 248

Query: 749 GKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
            ++PA +ALR+ +Q G  VL KS NE+RIR N+ V+++ +  +
Sbjct: 249 KRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSE 291

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>P51857:AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogenase - Homo sapiens (Human)|
          Length = 326

 Score =  196 bits (498), Expect = 2e-49
 Identities = 117/315 (37%), Positives = 174/315 (55%), Gaps = 20/315 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEP-----GVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKK 244
           L+ G  IP +GLGT+ SEP     G    +V  A+  GYRHID A +Y NE E+G A+++
Sbjct: 12  LSDGNSIPIIGLGTY-SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIRE 70

Query: 245 VFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAG 424
              EG   R+D+F   KLW TNH PE V   L+ TL+ LQ DYVDLY++  P+  K G  
Sbjct: 71  KIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE 130

Query: 425 FNPEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPA 580
             P +         +++ ATW AME+  D+G  +++GVSNF+ +++E +L     +  P 
Sbjct: 131 IYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPV 190

Query: 581 ANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPG-----TFKAFSVLEHPVVVSTAEK 745
           +NQVECHP + Q KL   C    I  +AYSPLG+          +  +L+  ++ S  ++
Sbjct: 191 SNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKR 250

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEI-EQAKLIR 922
             KT AQ+ LR+ +Q G  V+PKS N ERI+ N  ++D+S+  +       + +  + + 
Sbjct: 251 YNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVE 310

Query: 923 GKFW-THPEGVFKSE 964
              W  HPE  F  E
Sbjct: 311 LLMWRDHPEYPFHDE 325

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>Q96JD6:AKCL2_HUMAN Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens|
           (Human)
          Length = 320

 Score =  195 bits (496), Expect = 3e-49
 Identities = 109/290 (37%), Positives = 159/290 (54%), Gaps = 33/290 (11%)
 Frame = +2

Query: 98  IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 277
           IP+VGL +W++ PG V +AV  A+ AGYRH DCA  Y NE+E+G  ++    EG   R+D
Sbjct: 4   IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63

Query: 278 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPEN------ 439
           LFI +KLWCT H    V  A   +L+ L+ +Y+DLYL+HWP+      GF P +      
Sbjct: 64  LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM------GFKPPHPEWIMS 117

Query: 440 -----------------------VIPADIP--ATWAAMESLYDSGKARAIGVSNFSCKKV 544
                                  VIP+D     TW AME L  +G  + IGVSNF+ +++
Sbjct: 118 CSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQL 177

Query: 545 EELL--AVARVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEH 718
           E LL     R  P  NQ+ECHP   Q  L   C S+ +  +AY PLG  G+ +   ++++
Sbjct: 178 ERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG--GSCEGVDLIDN 235

Query: 719 PVVVSTAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI 868
           PV+   A++ GK+PAQ+ +R+ +Q    V+P S     I+ NI V+D+ +
Sbjct: 236 PVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFEL 285

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>Q4R802:AKCL2_MACFA Aldo-keto reductase family 1 member C-like protein 2 - Macaca|
           fascicularis (Crab eating macaque) (Cynomolgus monkey)
          Length = 320

 Score =  194 bits (493), Expect = 6e-49
 Identities = 110/290 (37%), Positives = 155/290 (53%), Gaps = 33/290 (11%)
 Frame = +2

Query: 98  IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 277
           IP+VGL  W++ PG V +AV  A+ AGYRH +CA  Y NEKE+G  ++    EG   R+D
Sbjct: 4   IPAVGLSCWKASPGKVTEAVKVAIDAGYRHFNCAYFYHNEKEVGAGIRYKIKEGAVRRED 63

Query: 278 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP-------- 433
           LFI SKLWCT H    V  A   +L+ L+ +Y+DLYL+HWP+      GF P        
Sbjct: 64  LFIASKLWCTCHKKSLVKTACRRSLKALKLNYLDLYLIHWPM------GFKPPHPEWIMS 117

Query: 434 ---------------------ENVIPADIP--ATWAAMESLYDSGKARAIGVSNFSCKKV 544
                                + VIP D     TW AME L  +G  + IGVSNF+ +++
Sbjct: 118 CSELSFCLSHPGVHDLPLDESDMVIPGDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQL 177

Query: 545 EELL--AVARVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEH 718
           E LL     R  P  NQ+ECHP   Q  L   C S+G+  +AY PLG  G+ +   +++ 
Sbjct: 178 ERLLNKPGLRFKPVTNQIECHPYLTQKNLISFCQSRGVSVTAYRPLG--GSCEGVDLIDD 235

Query: 719 PVVVSTAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI 868
           PV+   A++  K+PAQ+ +R+  Q    V+P S     I+ NI V+D+ +
Sbjct: 236 PVIQRIAKEHSKSPAQILIRFQTQRNVIVIPGSITPSHIKENIQVFDFEL 285

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>Q8K023:AKC1H_MOUSE Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse)|
          Length = 323

 Score =  192 bits (488), Expect = 2e-48
 Identities = 111/282 (39%), Positives = 165/282 (58%), Gaps = 16/282 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  IP +G GT+ +E  +   ++ +   A+  G+ HIDC+ +Y NE+EIG A+    
Sbjct: 10  LNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
           ++G   R+D+F TSKLW T+H PE V  +L+ +L+ L  DYVDLYL+H+P+ +K G    
Sbjct: 70  EDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELL 129

Query: 431 PE----NVI--PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P+    N+I    D+  TW AME   D+G A++IGVSNF+ +++E +L     +  P  N
Sbjct: 130 PKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS-----VLEHPVVVSTAEKLG 751
           QVECH    Q+KL   C    I   AY  LG+       +     +L+ PV+ + A+K  
Sbjct: 190 QVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPVLCAMAKKYK 249

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           +TPA +ALR+ +  G   L KS NEERIR N+ V+D+ +  D
Sbjct: 250 RTPALIALRYQLDRGIVALAKSFNEERIRENMQVFDFQLASD 291

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>Q876L8:XYL1_TRIRE NAD(P)H-dependent D-xylose reductase - Trichoderma reesei (Hypocrea|
           jecorina)
          Length = 324

 Score =  191 bits (486), Expect = 4e-48
 Identities = 113/296 (38%), Positives = 162/296 (54%), Gaps = 21/296 (7%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LN+G  +P VG G W+ +  V  D VY A+KAGYR  D A  YGNEKE G  + +   +G
Sbjct: 8   LNSGYDMPQVGFGLWKVDNAVCADTVYNAIKAGYRLFDGACDYGNEKECGEGVARAIKDG 67

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP---------IRMK 412
           +  R+DLFI SKLW T H  + V       L D Q DY DL+LVH+P         +R  
Sbjct: 68  LVKREDLFIVSKLWQTFHDEDKVEPITRRQLADWQIDYFDLFLVHFPAALEYVDPSVRYP 127

Query: 413 KGAGFNPENVI----PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPA 580
            G  ++ ++ +       +  TW AME L D G AR+IGVSN+  + V + L  AR+ PA
Sbjct: 128 PGWFYDGKSEVRWSKTTTLQQTWGAMERLVDKGLARSIGVSNYQAQSVYDALIYARIKPA 187

Query: 581 ANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTF-----KAFSV---LEHPVVVST 736
             Q+E HP  QQ  L  L  ++GI  +AYS  G  G       +A SV   ++ PV+ + 
Sbjct: 188 TLQIEHHPYLQQPDLVSLAQTEGIVVTAYSSFGPTGFMELDMPRAKSVAPLMDSPVIKAL 247

Query: 737 AEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIE 904
           A+K  +TPAQV LRW  Q G +V+PK++  E +  N+D   + +  +  A  ++++
Sbjct: 248 ADKHRRTPAQVLLRWATQRGIAVIPKTSRPEVMAQNLDNTSFDLDSEDLAKIADMD 303

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>Q8VCX1:AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogenase - Mus musculus (Mouse)|
          Length = 325

 Score =  188 bits (478), Expect = 3e-47
 Identities = 115/314 (36%), Positives = 170/314 (54%), Gaps = 19/314 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKA----GYRHIDCAQVYGNEKEIGFALKKV 247
           L+ G  IP +GLGT+ S+P  V    Y AVK     GYRHID A VY NE E+G A+++ 
Sbjct: 12  LSDGNNIPLIGLGTY-SDPRPVPGKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREK 70

Query: 248 FDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGF 427
             EG   R+++F   KLW T H P  V  AL+ TL+ L+ DY+DLY++  P+  K G   
Sbjct: 71  IAEGKVKREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFKPGKEI 130

Query: 428 NPEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAA 583
            P +          ++ ATW A+E+  D+G  +++GVSNF+ +++E +L     +  P  
Sbjct: 131 YPRDENGRIIYDKTNLCATWEALEACKDAGLVKSLGVSNFNRRQLELILNKPGLKYKPVT 190

Query: 584 NQVECHPVWQQAKLRDLCASKGIHFSAYSPLG---SPGTFKAFS--VLEHPVVVSTAEKL 748
           NQVECHP + Q KL   C    I   A+SPLG   +P      S  +L   ++ S  +K 
Sbjct: 191 NQVECHPYFTQTKLLKFCQQHDIVIVAHSPLGTCRNPSWVNVSSPPLLNDELLTSLGKKY 250

Query: 749 GKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEI-EQAKLIRG 925
            KT AQ+ LR+ +Q G  V+PKS   ERI+ N  ++D+S+  +       + +  + +  
Sbjct: 251 NKTQAQIVLRFNIQRGIVVIPKSFTPERIKENFQIFDFSLTEEEMKDIDALNKNVRYVEL 310

Query: 926 KFWT-HPEGVFKSE 964
             W+ HPE  F  E
Sbjct: 311 LMWSDHPEYPFHDE 324

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>P28475:S6PD_MALDO NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus|
           domestica (Apple) (Malus sylvestris)
          Length = 310

 Score =  188 bits (477), Expect = 4e-47
 Identities = 98/277 (35%), Positives = 160/277 (57%), Gaps = 14/277 (5%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           L++G ++P +GLG W+ E   + + +  A+K GYRH DCA  Y +E ++G AL + F  G
Sbjct: 6   LSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFKTG 65

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPEN 439
           +  R++LFIT+K+W ++H    V  A   +L+ LQ DY+DLYLVH+P+  K  A     +
Sbjct: 66  LVKREELFITTKIWNSDHG--HVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTAS 123

Query: 440 VIPAD----------IPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQ 589
           ++  D          +  TW  ME     G  R+IG+SN+      + LA +++ PA +Q
Sbjct: 124 LLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQ 183

Query: 590 VECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGT----FKAFSVLEHPVVVSTAEKLGKT 757
            E HP +Q+  L   C   G+  +A++PLG        F + S L+ PV+   A+K GK+
Sbjct: 184 FETHPYFQRDSLVKFCMKHGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVAKKYGKS 243

Query: 758 PAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI 868
            AQ+ LRWG+Q   +V+PKS+  +R++ N++V ++ +
Sbjct: 244 VAQICLRWGIQRKTAVIPKSSKIQRLKENLEVLEFQL 280

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>P02532:CRO_RANTE Rho crystallin - Rana temporaria (European common frog)|
          Length = 324

 Score =  187 bits (476), Expect = 6e-47
 Identities = 112/314 (35%), Positives = 168/314 (53%), Gaps = 19/314 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSE---PGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  +P +GLGT+ S      +  +AV  A+  GYRHIDCA + GNE  IG  ++   
Sbjct: 11  LNDGNMMPILGLGTYASPHVPKSLAEEAVKIAIDVGYRHIDCAFITGNEMHIGNGIRSKI 70

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F T KLWCT  +PE V   L+ +L+D+  DY+DL+L+HWP+ +K     +
Sbjct: 71  SDGTVKREDIFYTGKLWCTYFSPEMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASD 130

Query: 431 PEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P +          D+ ATW A+E+  D+G  R++GVSNF+ +++E +L     +  P  N
Sbjct: 131 PSDKDKPFIYDNVDLCATWEALEARKDAGLVRSLGVSNFNRRQLERILNKPGLKYKPVCN 190

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPG-----TFKAFSVLEHPVVVSTAEKLG 751
           QVECH    Q KL   C SK I    YS LGS             +L+ P++   A K  
Sbjct: 191 QVECHVYLNQNKLHSYCKSKDIVLVTYSVLGSHRDRNWVDLSLPVLLDDPILNKVAAKYN 250

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAKLIRGKF 931
           +T A++A+R+ +Q G  VL KS    RI+ N+ V+++ +  +       +++  L  G F
Sbjct: 251 RTSAEIAMRFILQKGIVVLAKSFTPARIKQNLGVFEFELKPEDMKSLESLDR-NLHYGPF 309

Query: 932 ---WTHPEGVFKSE 964
                HPE  F  E
Sbjct: 310 REVKQHPEYPFHDE 323

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>P17264:CRO_RANCA Rho crystallin - Rana catesbeiana (Bull frog)|
          Length = 324

 Score =  185 bits (470), Expect = 3e-46
 Identities = 113/323 (34%), Positives = 170/323 (52%), Gaps = 28/323 (8%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEP---GVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  +P +GLGT+ +      +  +AV  A+  GYRHIDCA + GNE  IG  ++   
Sbjct: 11  LNDGNMMPILGLGTYAAPDVPKSLAEEAVKTAIDVGYRHIDCAFITGNEMHIGNGIRSKI 70

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+D+F T KLWCT  +P+ V   L+ +L+D+  DY+DL+L+HWP+ +K     +
Sbjct: 71  SDGTVKREDIFYTGKLWCTYFSPDMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASD 130

Query: 431 PEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P +          D+ ATW A+E+  D+G  R++GVSNF+ +++E +L     +  P  N
Sbjct: 131 PSDKDKPFIYDNVDLCATWEALEARKDAGLVRSLGVSNFNRRQLERILNKPGLKYKPVCN 190

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPG-----TFKAFSVLEHPVVVSTAEKLG 751
           QVECH    Q KL   C SK I    YS LGS             +L+ P++   A K  
Sbjct: 191 QVECHVYLNQNKLHSYCKSKDIVLVTYSVLGSHRDRNWVDLSLPVLLDDPILNKIAAKYN 250

Query: 752 KTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI-PGDL-----------FAGFS 895
           +T A+VA+R+ +Q G  VL KS    RI+ N+ V+++ + P D+           +  F 
Sbjct: 251 RTSAEVAMRFILQKGIVVLAKSFTPARIKQNLGVFEFELKPEDMKTLESLDRNLHYGPFR 310

Query: 896 EIEQAKLIRGKFWTHPEGVFKSE 964
           E++Q          HPE  F  E
Sbjct: 311 EVKQ----------HPEYPFHDE 323

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>P23457:DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase - Rattus norvegicus (Rat)|
          Length = 322

 Score =  184 bits (468), Expect = 5e-46
 Identities = 109/288 (37%), Positives = 163/288 (56%), Gaps = 16/288 (5%)
 Frame = +2

Query: 62  MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGF 232
           ++L   LN G  IP +G GT   E     + + A   A+  G+RH D A +Y  E+E+G 
Sbjct: 4   ISLRVALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQ 63

Query: 233 ALKKVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 412
           A++   ++G   R+D+F TSKLW T H PE V   L+ TL+  Q DYVDLY++H+P+ ++
Sbjct: 64  AIRSKIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQ 123

Query: 413 KGAGFNPEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVAR 568
            G  F P +          DI  TW AME   D+G A++IGVSNF+C+++E +L     +
Sbjct: 124 PGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLK 183

Query: 569 VTPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPG-----TFKAFSVLEHPVVVS 733
             P  NQVECH    Q+K+ D C SK I   +Y  LGS         K+  +L+ PV+ +
Sbjct: 184 YKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPVLCA 243

Query: 734 TAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
            A+K  +TPA VALR+ +Q G   L +S N +RI+    V+++ +  +
Sbjct: 244 IAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASE 291

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>P38715:GRE3_YEAST NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae|
           (Baker's yeast)
          Length = 327

 Score =  183 bits (464), Expect = 1e-45
 Identities = 106/284 (37%), Positives = 155/284 (54%), Gaps = 26/284 (9%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LN G K+P VGLG W+ +  V  + +Y A+K GYR  D A  YGNEKE+G  ++K   EG
Sbjct: 7   LNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEG 66

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK--------- 412
           + +RKD+F+ SKLW   H P+ V +AL  TL D+  DY+DLY +H+PI  K         
Sbjct: 67  LVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYP 126

Query: 413 ----KGAGFNPE-NVIPADIPA--TWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARV 571
                GA    + ++  A +P   T+ A+E   D G  ++IGVSNF    +++LL   R+
Sbjct: 127 PGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRI 186

Query: 572 TPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF---------SVLEHPV 724
            P A Q+E HP   Q  L + C    I   AYS  G P +F            ++ E+ V
Sbjct: 187 KPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFG-PQSFIEMDLQLAKTTPTLFENDV 245

Query: 725 VVSTAEK-LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDV 853
           +   ++   G T +QV LRW  Q G +V+PKS+ +ER+  N+++
Sbjct: 246 IKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEI 289

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>Q9TV64:AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogenase - Oryctolagus cuniculus|
           (Rabbit)
          Length = 326

 Score =  183 bits (464), Expect = 1e-45
 Identities = 115/315 (36%), Positives = 166/315 (52%), Gaps = 20/315 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEP-----GVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKK 244
           L  G  IP +GLGT+ SEP     G    +V  A+  GYRHID A +Y NE E+G   ++
Sbjct: 12  LGDGNSIPIIGLGTY-SEPKTTPKGSCATSVKIAIDTGYRHIDGAYIYQNEHEVGETFRE 70

Query: 245 VFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAG 424
              EG   R+D+F   KLW TNH P  V   L+ TL+ L+ DY+DLY++  P+  K G  
Sbjct: 71  KIAEGKVRREDIFYCGKLWATNHDPVMVRPTLERTLKVLKLDYIDLYIIEIPMAFKPGDV 130

Query: 425 FNPEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPA 580
             P +          ++ ATW A+E+  D+G  +++GVSNF+ +++E LL     +  P 
Sbjct: 131 VYPRDENGKWLYHKTNLCATWEALEACKDAGLVKSLGVSNFNRQQLELLLNKPGLKHKPV 190

Query: 581 ANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPG-----TFKAFSVLEHPVVVSTAEK 745
            NQVECHP + Q KL   C    I   AYSPLG+             +L+  ++ S  +K
Sbjct: 191 CNQVECHPYFTQPKLLKFCQQHDIIIVAYSPLGTCRNPMWVNTSLPPLLKDTLLNSLGKK 250

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEI-EQAKLIR 922
             KT AQ+ LR+ VQ G  V+PKS N ERI+ N  ++D+S+  +       + +  + + 
Sbjct: 251 YKKTAAQIVLRFNVQRGVVVIPKSFNPERIKENFQIFDFSLTEEEMKDIEALNKNVRYVE 310

Query: 923 GKFW-THPEGVFKSE 964
              W  HPE  F  E
Sbjct: 311 LLMWRDHPEYPFNDE 325

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>Q01213:DTDH_MUCMU 4-dihydromethyl-trisporate dehydrogenase - Mucor mucedo|
          Length = 321

 Score =  182 bits (463), Expect = 2e-45
 Identities = 104/280 (37%), Positives = 152/280 (54%), Gaps = 22/280 (7%)
 Frame = +2

Query: 86  TGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVT 265
           TG K+P  G G W+ +     + VY A+K GYR  D A  YGNE E+G  + K  +EG+ 
Sbjct: 11  TGDKMPIRGFGCWKIDTKDCEETVYQAIKTGYRLFDGACDYGNEVEVGRGINKAINEGLV 70

Query: 266 TRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVI 445
            R+DLFI +KLW T H+ + V    D  L+D   +Y DLYL+H+P+ ++     +P  V 
Sbjct: 71  KREDLFIVTKLWNTFHSKKHVRALFDRQLKDTGLEYFDLYLIHFPVPLQY---VDPATVY 127

Query: 446 P---------------ADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPA 580
           P               + I   WA +E + D+G AR IGV+NF+C+ + +LL  AR+ PA
Sbjct: 128 PPGWYVGDAKSLQFEQSPIHECWAELEKIVDAGLARNIGVANFNCQAILDLLTYARIKPA 187

Query: 581 ANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPG------TFKAF-SVLEHPVVVSTA 739
             Q+E HP   Q +L      +GI  +AYS  G         + K + S+LEH  V S A
Sbjct: 188 VLQIELHPYLPQERLVKWVKEQGIQITAYSSFGPTSYVDLTESGKTYTSLLEHASVKSVA 247

Query: 740 EKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYD 859
           +K   +  QV LRW +    +V+PKS N  R++AN+++ D
Sbjct: 248 DKHNVSTGQVLLRWALDREFAVIPKSVNAGRMKANLEILD 287

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>Q8VC28:AK1CD_MOUSE Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse)|
          Length = 323

 Score =  179 bits (454), Expect = 2e-44
 Identities = 117/314 (37%), Positives = 170/314 (54%), Gaps = 19/314 (6%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKA---GYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  IP++G GT++ +      ++ AA  A   GYRH+D A  Y  E+EIG A++   
Sbjct: 10  LNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKI 69

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
             GV  R+DLFIT+KLWCT   PE V  AL+ +L+ LQ DYVDLY++H+P+ MK G    
Sbjct: 70  KAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDF 129

Query: 431 PEN------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAAN 586
           P N      +   D   TW  +E   D+G  ++IGVSNF+ +++E +L     +  P  N
Sbjct: 130 PVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCN 189

Query: 587 QVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF------SVLEHPVVVSTAEKL 748
           QVECH    Q KL D C SK I   AY  LG+   +K +       +L  PV+   A+K 
Sbjct: 190 QVECHLYLNQRKLLDYCESKDIVLVAYGALGTQ-RYKEWVDQNSPVLLNDPVLCDVAKKN 248

Query: 749 GKTPAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI-PGDLFAGFSEIEQAKLIRG 925
            ++PA +ALR+ +Q G   L +S  E  +R N+ V+ + + P D+       +  + +  
Sbjct: 249 KRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFRYLPA 308

Query: 926 KFWT-HPEGVFKSE 964
           +F   HPE  F  E
Sbjct: 309 EFLVDHPEYPFVEE 322

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>P06632:DKGA_CORSC 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp.|
           (strain ATCC 31090)
          Length = 278

 Score =  178 bits (452), Expect = 4e-44
 Identities = 109/292 (37%), Positives = 151/292 (51%)
 Frame = +2

Query: 77  VLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDE 256
           VLN G  IP +G G ++  P     AV  A++ GYRHID A +YGNE+ +G A+      
Sbjct: 7   VLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAA---S 63

Query: 257 GVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 436
           G+  R DLFIT+KLW   H  ++   A+  +L  L  D VDLYLVHWP           +
Sbjct: 64  GIA-RDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAA-------D 115

Query: 437 NVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQ 616
           N + A     W  M  L  +G  R+IGVSN     +E ++A   V PA NQ+E HP +QQ
Sbjct: 116 NYVHA-----WEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQ 170

Query: 617 AKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAG 796
            ++ D  A+  +   ++ PLG  G +  F     PV  + A   GKTPAQ  LRW +Q G
Sbjct: 171 REITDWAAAHDVKIESWGPLGQ-GKYDLFGA--EPVTAAAAAH-GKTPAQAVLRWHLQKG 226

Query: 797 HSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAKLIRGKFWTHPEGV 952
             V PKS   ER+  N+DV+D+ +     A    ++      G+   HP+ V
Sbjct: 227 FVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDAMDPGD-GSGRVSAHPDEV 277

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>Q46857:DKGA_ECOLI 2,5-diketo-D-gluconic acid reductase A - Escherichia coli|
          Length = 275

 Score =  171 bits (433), Expect = 6e-42
 Identities = 102/279 (36%), Positives = 149/279 (53%), Gaps = 1/279 (0%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           L  G  +P +GLG WQ+    V  A+  A++ GYR ID A  Y NE+ +G ALK      
Sbjct: 9   LQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALKNAS--- 65

Query: 260 VTTRKDLFITSKLWCTNHA-PEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 436
              R++LFIT+KLW  +H  P +   AL  +L+ LQ DY+DLYL+HWP+          +
Sbjct: 66  -VNREELFITTKLWNDDHKRPRE---ALLDSLKKLQLDYIDLYLMHWPVPAI-------D 114

Query: 437 NVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQ 616
           + + A     W  M  L   G  ++IGV NF    ++ L+    VTP  NQ+E HP+ QQ
Sbjct: 115 HYVEA-----WKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQIELHPLMQQ 169

Query: 617 AKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAG 796
            +L    A+  I   ++SPL   G      V +  V+   A+K GKTPAQ+ +RW + +G
Sbjct: 170 RQLHAWNATHKIQTESWSPLAQGGK----GVFDQKVIRDLADKYGKTPAQIVIRWHLDSG 225

Query: 797 HSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAK 913
             V+PKS    RI  N DV+D+ +  D     ++++Q K
Sbjct: 226 LVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGK 264

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>Q8XBT6:DKGA_ECO57 2,5-diketo-D-gluconic acid reductase A - Escherichia coli O157:H7|
          Length = 275

 Score =  169 bits (429), Expect = 2e-41
 Identities = 101/279 (36%), Positives = 148/279 (53%), Gaps = 1/279 (0%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           L  G  +P +GLG WQ+    V  A+  A++ GYR  D A  Y NE+ +G ALK      
Sbjct: 9   LQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSFDTAAAYKNEEGVGKALKNAS--- 65

Query: 260 VTTRKDLFITSKLWCTNH-APEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 436
              R++LFIT+KLW  +H  P +   AL  +L+ LQ DY+DLYL+HWP+          +
Sbjct: 66  -VNREELFITTKLWNDDHNRPRE---ALLDSLKKLQLDYIDLYLMHWPVPAI-------D 114

Query: 437 NVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQ 616
           + + A     W  M  L   G  ++IGV NF    ++ L+    VTP  NQ+E HP+ QQ
Sbjct: 115 HYVEA-----WKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQIELHPLMQQ 169

Query: 617 AKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAG 796
            +L    A+  I   ++SPL   G      V +  V+   A+K GKTPAQ+ +RW + +G
Sbjct: 170 RQLHAWNATHKIQTESWSPLAQGGK----GVFDQKVIRDLADKYGKTPAQIVIRWHLDSG 225

Query: 797 HSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAK 913
             V+PKS    RI  N DV+D+ +  D     ++++Q K
Sbjct: 226 LVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGK 264

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>Q8ZM06:DKGA_SALTY 2,5-diketo-D-gluconic acid reductase A - Salmonella typhimurium|
          Length = 275

 Score =  166 bits (419), Expect = 2e-40
 Identities = 99/278 (35%), Positives = 147/278 (52%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           L  G  +P +GLG W++    V  A++ A++ GYR ID A  Y NE+ +G ALK      
Sbjct: 9   LQDGNVMPQLGLGVWKASNEEVIAAIHKALEVGYRSIDTATAYQNEEGVGKALKAAS--- 65

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPEN 439
              R++LFIT+KLW  N   +    AL  +L+ LQ DY+DLYL+HWP+          ++
Sbjct: 66  -VAREELFITTKLW--NDDQKRPREALQESLKKLQLDYLDLYLMHWPVPAI-------DH 115

Query: 440 VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQA 619
            + A     W  M +L   G  ++IGV NF    ++ L+    VTP  NQ+E HP+ QQ 
Sbjct: 116 YVDA-----WKGMIALQKEGLVKSIGVCNFQIHHLQRLIDETGVTPVINQIELHPLMQQR 170

Query: 620 KLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAGH 799
           +L    A+  I   ++SPL   G      V +  V+   A+K GKTPAQ+ +RW +  G 
Sbjct: 171 QLHAWNATHKIQTESWSPLAQGGE----GVFDQKVIRELADKYGKTPAQIVIRWHLDCGL 226

Query: 800 SVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAK 913
            V+PKS    RI  N  V+D+ +  D     ++++Q K
Sbjct: 227 VVIPKSVTPSRIAENFAVWDFRLDKDELGEIAKLDQGK 264

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>P82809:AK1CD_MESAU Aldo-keto reductase family 1 member C13 - Mesocricetus auratus|
           (Golden hamster)
          Length = 322

 Score =  165 bits (417), Expect = 4e-40
 Identities = 107/311 (34%), Positives = 167/311 (53%), Gaps = 19/311 (6%)
 Frame = +2

Query: 89  GAKIPSVGLGTWQS---EPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           G  IP++G GT++          +A   A+  GYRHID A  Y  E+EIG A++     G
Sbjct: 13  GHCIPALGFGTYKPIEVPKSKAMEAANLAIGVGYRHIDTAYAYQIEEEIGQAIQSNIKAG 72

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPEN 439
           +  R+D+FIT+KLWCT   PE V  +L+     LQ ++VDL+++H+P+ MK G    P +
Sbjct: 73  IVKREDMFITTKLWCTCFQPELVRPSLEKXXXKLQLEHVDLFIMHYPVPMKAGDNDFPLD 132

Query: 440 ------VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAANQVE 595
                 +   D  ATW A+E   D+G  ++IGVSNF+ +++E +L     +  P  NQVE
Sbjct: 133 EQGKLLLDTVDFCATWEALEKXXDAGLVKSIGVSNFNMRQLERILNKPGLKYKPVCNQVE 192

Query: 596 CHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAF------SVLEHPVVVSTAEKLGKT 757
           CH    Q+KL D C SK I   A+  LG+   +K +       +L  PV+   A+   ++
Sbjct: 193 CHVYNNQSKLLDYCKSKDIVLVAFGALGTQ-RYKEWVDQDSPVLLNDPVLCGGAKXXXRS 251

Query: 758 PAQVALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI-PGDLFAGFSEIEQAKLIRGKFW 934
           PA +ALR+ VQ G   L +S  E  ++ N+ V+++ + P D+       +  + +  +F+
Sbjct: 252 PALIALRYLVQRGVVPLAQSFYESEMKENLQVFEFQLSPEDMKILDGLNKNFRYLPAQFF 311

Query: 935 T-HPEGVFKSE 964
             HPE  F  E
Sbjct: 312 ADHPEYPFSEE 322

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>Q02198:MORA_PSEPU Morphine 6-dehydrogenase - Pseudomonas putida|
          Length = 296

 Score =  164 bits (415), Expect = 7e-40
 Identities = 104/285 (36%), Positives = 154/285 (54%), Gaps = 10/285 (3%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           LN G K+P++GLG + +       A+ +A+ +GYR ID A+ Y NE ++G  ++   + G
Sbjct: 10  LNNGVKMPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGEGIR---NSG 66

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPEN 439
           V  R ++F+T+KL+  ++  E    A D +L  L  DYVDLYL+HWP +           
Sbjct: 67  VD-RAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWPTK----------- 114

Query: 440 VIPADIPAT---WAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVW 610
               D  AT   W A E +   G+ARAIGV NF   +++EL+A + V PA NQ+E HP +
Sbjct: 115 ----DWNATIQSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQIELHPYF 170

Query: 611 QQAKLRDLCASKGIHFSAYSPLG---SPGTFKAFSVLEH----PVVVSTAEKLGKTPAQV 769
            Q  L     + GI   A+SP+G   + G        +H    PV+ + AE  G++ AQV
Sbjct: 171 AQKPLLAKNRALGIVTEAWSPIGGAINDGDGDNHGGRKHPLTDPVITTIAEAHGRSAAQV 230

Query: 770 ALRWGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIE 904
            LRW  Q     +PKS N ERI  NIDV+D+++     A   E++
Sbjct: 231 ILRWHFQNDVVAIPKSVNPERIAKNIDVFDFALSDAEMAQLDELD 275

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>Q8ZI40:DKGA_YERPE 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis|
          Length = 277

 Score =  163 bits (413), Expect = 1e-39
 Identities = 97/279 (34%), Positives = 148/279 (53%), Gaps = 1/279 (0%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           L  G  +P +GLG WQ+       AV  A++ GYR ID A +Y NE+ +G ALK      
Sbjct: 9   LYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKALKAA---- 64

Query: 260 VTTRKDLFITSKLWCTN-HAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 436
              R +LFIT+KLW  + H P+    AL+ +LQ LQ DYVDLYL+HWP         +P+
Sbjct: 65  AVARDELFITTKLWNDDQHNPQQ---ALETSLQKLQLDYVDLYLIHWP---------DPK 112

Query: 437 NVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQ 616
                   + W  + +L + G  R+IGV NF    ++ L+    + P  NQ+E HP+ QQ
Sbjct: 113 Q---DHYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIELHPLLQQ 169

Query: 617 AKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAG 796
            +L    A+  I   ++SPL   G      V +  ++   A++  KTPAQ+ +RW + +G
Sbjct: 170 RQLHAWNATHHIATESWSPLAQGGK----GVFDQEIIRKLAQQYNKTPAQIVIRWHLDSG 225

Query: 797 HSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAK 913
             V+PKS    RIR N +V+D+ +  +     ++++  K
Sbjct: 226 LIVIPKSVTPARIRENFEVFDFKLQKEELLAITKLDCGK 264

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>P58744:DKGA_SALTI 2,5-diketo-D-gluconic acid reductase A - Salmonella typhi|
          Length = 275

 Score =  163 bits (413), Expect = 1e-39
 Identities = 98/278 (35%), Positives = 146/278 (52%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG 259
           L  G  +P +GLG W++    V  A++ A++ GYR ID A  Y NE+ +G ALK      
Sbjct: 9   LQDGNVMPQLGLGVWKASNEEVIAAIHKALEVGYRSIDTATAYQNEEGVGKALKAAS--- 65

Query: 260 VTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPEN 439
              R++LFIT+KLW  N   +    AL  +L+ LQ DY+DLYL+HWP+          ++
Sbjct: 66  -VAREELFITTKLW--NDDQKRPREALQESLKKLQLDYLDLYLMHWPVPAI-------DH 115

Query: 440 VIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQA 619
            + A     W  M +L   G  ++IGV NF    ++ L+    V P  NQ+E HP+ QQ 
Sbjct: 116 YVDA-----WKGMIALQKEGLVKSIGVCNFQIHHLQRLIDETGVPPVINQIELHPLMQQR 170

Query: 620 KLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAGH 799
           +L    A+  I   ++SPL   G      V +  V+   A+K GKTPAQ+ +RW +  G 
Sbjct: 171 QLHAWNATHKIQTESWSPLAQGGE----GVFDQKVIRELADKYGKTPAQIVIRWHLDCGL 226

Query: 800 SVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAK 913
            V+PKS    RI  N  V+D+ +  D     ++++Q K
Sbjct: 227 VVIPKSVTPSRIAENFAVWDFRLDKDELGEIAKLDQGK 264

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>P38115:ARA1_YEAST D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces|
           cerevisiae (Baker's yeast)
          Length = 344

 Score =  160 bits (405), Expect = 1e-38
 Identities = 104/281 (37%), Positives = 153/281 (54%), Gaps = 20/281 (7%)
 Frame = +2

Query: 68  LHFVLNTGAKIPSVGLGTWQSEPGVVG--DAVYAAVKAGYRHIDCAQVYGNEKEIGFALK 241
           ++F LN G +IP++GLGT      +     AV AA+KAGYRHID A  Y  E  +G A+K
Sbjct: 23  IYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82

Query: 242 KVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPI---RMK 412
           ++ ++G   R+DLFIT+K+W      ++V  +L+ +L+ L  +YVDL L HWP+   ++K
Sbjct: 83  ELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140

Query: 413 KGAGFNPENVIPADIPA------------TWAAMESLY---DSGKARAIGVSNFSCKKVE 547
              G +     P D               T+  +E +Y   +  + RAIGVSNFS + +E
Sbjct: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200

Query: 548 ELLAVARVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVV 727
            L+   RV P  NQVE HP   Q +LR  C    I  +AYSPLGS G       L+ P+V
Sbjct: 201 RLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGA----PNLKIPLV 256

Query: 728 VSTAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIRANID 850
              AEK   T   + + + ++ G  V+P+S N  RI ++I+
Sbjct: 257 KKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE 297

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>Q09632:YOF5_CAEEL Probable oxidoreductase ZK1290.5 - Caenorhabditis elegans|
          Length = 321

 Score =  158 bits (400), Expect = 4e-38
 Identities = 97/270 (35%), Positives = 148/270 (54%), Gaps = 3/270 (1%)
 Frame = +2

Query: 77  VLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVK-AGYRHIDCAQVYGNEKEIGFALKKVFD 253
           VL+   ++P +GLGT  S  G   DAV  ++K  GYR ID A+ YG EK++G A+K    
Sbjct: 6   VLSNNVEMPLIGLGTTHSG-GYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAVKNCS- 63

Query: 254 EGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 433
                R+++F+++KLW  +   ++V  A   + + LQTDY+D+Y++H P          P
Sbjct: 64  ---VPREEMFLSTKLWPVD-CGDEVYNAFQTSCEKLQTDYLDMYMIHMPQL--------P 111

Query: 434 ENVI--PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPV 607
           + ++        TW  ME LY+    R+IGVSN+S + ++ELL  A + P ANQVE HP 
Sbjct: 112 DWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHANQVELHPW 171

Query: 608 WQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGV 787
           + QA L++ C   GI    Y PL           LE   +   A K  K+PAQ+ LRW +
Sbjct: 172 FHQADLKNYCDELGILTMGYCPLAKG------KYLEDETLCKIASKYQKSPAQICLRWSI 225

Query: 788 QAGHSVLPKSTNEERIRANIDVYDWSIPGD 877
           Q     +PKST+  R++ N +V+D+ +  +
Sbjct: 226 QQNVPTVPKSTDCRRLKENTNVFDFELSAE 255

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>P47137:YJ66_YEAST Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's|
           yeast)
          Length = 282

 Score =  150 bits (380), Expect = 8e-36
 Identities = 95/307 (30%), Positives = 156/307 (50%), Gaps = 5/307 (1%)
 Frame = +2

Query: 74  FVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFD 253
           + L+ G KIPS+ LGT+        + VY  VK GYRH D A +YGNEKE+G  + K  +
Sbjct: 6   YKLSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLN 65

Query: 254 E--GVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQ-TDYVDLYLVHWPIRMKKGAG 424
           E  G   R+++F T+KLW + +  +    A+   L ++    Y+DL L+H P+   +G+ 
Sbjct: 66  EDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL---EGSK 122

Query: 425 FNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAANQVEC 598
              E         TW AM+   D G  ++IGVSN+  K ++ELL     +  P  NQ+E 
Sbjct: 123 LRLE---------TWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEI 173

Query: 599 HPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALR 778
            P   + +L D C SKG+   A++PL     +K    + +P ++   +++ + P QV +R
Sbjct: 174 SPWIMRQELADYCKSKGLVVEAFAPLCH--GYK----MTNPDLLKVCKEVDRNPGQVLIR 227

Query: 779 WGVQAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAKLIRGKFWTHPEGVFK 958
           W +Q G+  LPK+   +R+  N+  Y++ +  +              + KF  HP+    
Sbjct: 228 WSLQHGYLPLPKTKTVKRLEGNLAAYNFELSDE--------------QMKFLDHPDAYEP 273

Query: 959 SEEEIWD 979
           ++ E  D
Sbjct: 274 TDWECTD 280

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>P15339:DKGB_CORSS 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp.|
           (strain SHS752001)
          Length = 277

 Score =  148 bits (374), Expect = 4e-35
 Identities = 102/291 (35%), Positives = 144/291 (49%), Gaps = 2/291 (0%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTW--QSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFD 253
           LN G      GLGT+  + + GV   A+ AA+ +GYR +D A  Y NE E+G A++    
Sbjct: 9   LNDGRPFAEPGLGTYNLRGDEGVA--AMVAAIDSGYRLLDTAVNYENESEVGRAVRA--- 63

Query: 254 EGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 433
                R +L + SK+    H   +   ++ G+L  L  D +DL L+HWP         NP
Sbjct: 64  -SSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP---------NP 113

Query: 434 ENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQ 613
                 D   TW  M    ++G  R+IGVSNF+   ++ L+    VTPA NQVE HP + 
Sbjct: 114 SVGRWLD---TWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHPYFP 170

Query: 614 QAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQA 793
           QA LR      GI   ++SPL          +L+   VV      G TP QV LRW VQ 
Sbjct: 171 QAALRAFHDEHGIRTESWSPLARRSELLTEQLLQELAVV-----YGVTPTQVVLRWHVQL 225

Query: 794 GHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQAKLIRGKFWTHPE 946
           G + +PKS + +R R N DV+ +++  D     S +E+ +L  G   TH E
Sbjct: 226 GSTPIPKSADPDRQRENADVFGFALTADQVDAISGLERGRLWDGDPDTHEE 276

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>Q5T2L2:AKCL1_HUMAN Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens|
           (Human)
          Length = 302

 Score =  144 bits (364), Expect = 6e-34
 Identities = 99/281 (35%), Positives = 148/281 (52%), Gaps = 12/281 (4%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSE---PGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           LN G  +P +G GT+  +        +A   A+  G+RHID A +Y NE+E+G A+ +  
Sbjct: 13  LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72

Query: 251 DEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFN 430
            +G   R+++F T KLW T    E V  AL+ +L+ L  DYVDL+++H P  MK+     
Sbjct: 73  ADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPG--- 129

Query: 431 PENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELL--AVARVTPAANQ-VECH 601
            + ++P D             SG+     V      ++E +L     R  P  NQ VECH
Sbjct: 130 -KELLPKDA------------SGEIILETVELCDTWELELILNKPGLRYKPTCNQVVECH 176

Query: 602 PVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFS-----VLEHPVVVSTAEKLGKTPAQ 766
           P   Q+KL + C SK I   AYS LGS    +        +LE P++ S A+K  ++P Q
Sbjct: 177 PYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQ 236

Query: 767 VALRWGVQAGHSVLPKSTNEERIRANIDVYDWSI-PGDLFA 886
           VALR+ +Q G  VL KS ++ERI+ N  ++D+ + P D+ A
Sbjct: 237 VALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMKA 277

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>Q8X7Z7:DKGB_ECO57 2,5-diketo-D-gluconic acid reductase B - Escherichia coli O157:H7|
          Length = 267

 Score =  139 bits (351), Expect = 2e-32
 Identities = 89/254 (35%), Positives = 132/254 (51%), Gaps = 4/254 (1%)
 Frame = +2

Query: 98  IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 277
           IP+ GLGT++ +  VV  +V  A++ GYR ID AQ+Y NE  +G A+     E    R +
Sbjct: 3   IPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAAVGLAIA----ESGVPRHE 58

Query: 278 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADI 457
           L+IT+K+W  N + + +  +L  +LQ L+TDYVDL L+HWP               P D 
Sbjct: 59  LYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWP--------------SPNDE 104

Query: 458 PATWAAMESLYDS---GKARAIGVSNFSCKKVEE-LLAVARVTPAANQVECHPVWQQAKL 625
            +    M++L ++   G  R IG+SNF+   +E+ + AV     A NQ+E  P  Q  K+
Sbjct: 105 VSVEEFMQALLEAKKEGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKV 164

Query: 626 RDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAGHSV 805
                  GIH ++Y       T      L+  V+   A K   TPAQV L W +  G+SV
Sbjct: 165 VAWAKQHGIHITSYM------TLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV 218

Query: 806 LPKSTNEERIRANI 847
           +P ST  E + +N+
Sbjct: 219 IPSSTKRENLESNL 232

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>Q8ZRM7:DKGB_SALTY 2,5-diketo-D-gluconic acid reductase B - Salmonella typhimurium|
          Length = 267

 Score =  139 bits (349), Expect = 3e-32
 Identities = 88/258 (34%), Positives = 135/258 (52%), Gaps = 4/258 (1%)
 Frame = +2

Query: 98  IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 277
           IP+ GLGT++ +  VV  +V  A++ GYR +D AQ+Y NE  +G A+     E    R +
Sbjct: 3   IPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIA----ESGVPRNE 58

Query: 278 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADI 457
           L+IT+K+W  N + + +  +L  +L+ L+TDYVDL L+HWP               P D 
Sbjct: 59  LYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWP--------------SPGDA 104

Query: 458 PATWAAMESLYDS---GKARAIGVSNFSCKKVEE-LLAVARVTPAANQVECHPVWQQAKL 625
            +    M++L ++   G  R IG+SNF+   +E+ + AV     A NQ+E  P  Q  K+
Sbjct: 105 VSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADNIATNQIELSPYLQNRKV 164

Query: 626 RDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAGHSV 805
            D   + GIH ++Y       T      L+  V+   A K   TPAQV L W +  G+SV
Sbjct: 165 VDWAKAHGIHITSYM------TLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV 218

Query: 806 LPKSTNEERIRANIDVYD 859
           +P ST  E + +++   D
Sbjct: 219 IPSSTRRENLASSLLAQD 236

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>Q8Z988:DKGB_SALTI 2,5-diketo-D-gluconic acid reductase B - Salmonella typhi|
          Length = 267

 Score =  138 bits (347), Expect = 5e-32
 Identities = 88/258 (34%), Positives = 134/258 (51%), Gaps = 4/258 (1%)
 Frame = +2

Query: 98  IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 277
           IP+ GLGT++ +  VV  +V  A++ GYR +D AQ+Y NE  +G A+     E    R +
Sbjct: 3   IPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIA----ESGVPRNE 58

Query: 278 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADI 457
           L+IT+K+W  N + + +  +L  +L+ L+TDYVDL L+HWP               P D 
Sbjct: 59  LYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWP--------------SPGDA 104

Query: 458 PATWAAMESLYDS---GKARAIGVSNFSCKKVEE-LLAVARVTPAANQVECHPVWQQAKL 625
            +    M++L ++   G  R IG+SNF+   +E+ + AV     A NQ+E  P  Q  K+
Sbjct: 105 VSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADHIATNQIELSPYLQNRKV 164

Query: 626 RDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAGHSV 805
            D   + GIH ++Y       T      L+  V+   A K   TP QV L W +  G+SV
Sbjct: 165 VDWAKAHGIHITSYM------TLAYGKALKDEVIARIAVKHNATPVQVILAWAMGEGYSV 218

Query: 806 LPKSTNEERIRANIDVYD 859
           +P ST  E + +N+   D
Sbjct: 219 IPSSTRRENLASNLLAQD 236

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>Q8ZH36:DKGB_YERPE 2,5-diketo-D-gluconic acid reductase B - Yersinia pestis|
          Length = 267

 Score =  137 bits (346), Expect = 7e-32
 Identities = 85/251 (33%), Positives = 132/251 (52%), Gaps = 1/251 (0%)
 Frame = +2

Query: 98  IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 277
           IP  GLGT++ +  +V D+V  A+  GYR ID AQ+Y NE  +G A++    E    R +
Sbjct: 3   IPVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAIQ----ESGINRDE 58

Query: 278 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADI 457
           LFIT+K+W  N + + +  +L  ++Q L+TDYVDL L+HWP         +P + +   +
Sbjct: 59  LFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP---------SPNDEV--SV 107

Query: 458 PATWAAMESLYDSGKARAIGVSNFSCKKVEE-LLAVARVTPAANQVECHPVWQQAKLRDL 634
               + +      G  R IG+SNF+   +++ + AV     A NQ+E  P+ Q   + D 
Sbjct: 108 AEFMSELLKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNRNVVDF 167

Query: 635 CASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAGHSVLPK 814
               GI  ++Y       T      L  PV+ + AE+ G TPAQV L W +Q G+ V+P 
Sbjct: 168 AKQNGIAVTSYM------TLAYGKALAEPVIKTIAEQHGATPAQVILSWAMQLGYGVIPS 221

Query: 815 STNEERIRANI 847
           ST    + +N+
Sbjct: 222 STKAANLASNL 232

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>P30863:DKGB_ECOLI 2,5-diketo-D-gluconic acid reductase B - Escherichia coli|
          Length = 267

 Score =  137 bits (345), Expect = 9e-32
 Identities = 88/254 (34%), Positives = 132/254 (51%), Gaps = 4/254 (1%)
 Frame = +2

Query: 98  IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 277
           IP+ GLGT++ +  VV  +V  A++ GYR ID AQ+Y NE  +G A+     E    R +
Sbjct: 3   IPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAAVGQAIA----ESGVPRHE 58

Query: 278 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADI 457
           L+IT+K+W  N + + +  +L  +LQ L+TDYVDL L+HWP               P D 
Sbjct: 59  LYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWP--------------SPNDE 104

Query: 458 PATWAAMESLYDS---GKARAIGVSNFSCKKVEE-LLAVARVTPAANQVECHPVWQQAKL 625
            +    M++L ++   G  R IG+SNF+   +E+ + AV     A NQ+E  P  Q  K+
Sbjct: 105 VSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKV 164

Query: 626 RDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAGHSV 805
                  GIH ++Y       T      L+  V+   A K   TPAQV L W +  G+SV
Sbjct: 165 VAWAKQHGIHITSYM------TLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV 218

Query: 806 LPKSTNEERIRANI 847
           +P ST  + + +N+
Sbjct: 219 IPSSTKRKNLESNL 232

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>Q07551:KAR_YEAST NADPH-dependent alpha-keto amide reductase - Saccharomyces|
           cerevisiae (Baker's yeast)
          Length = 312

 Score =  119 bits (297), Expect = 3e-26
 Identities = 94/268 (35%), Positives = 124/268 (46%), Gaps = 16/268 (5%)
 Frame = +2

Query: 74  FVLNTGAKIPSV---GLGT-WQSEP--------GVVGDAVYAAVKAGYRHIDCAQVYGNE 217
           F LN G KIP++   G GT W             +V   VYA    G  HID A++Y   
Sbjct: 8   FTLNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTY 67

Query: 218 KEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 397
            E+G AL          R  +F+T K        +     LD  L+ + TDYVDLYL+H 
Sbjct: 68  PEVGKALSLT----EKPRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHS 123

Query: 398 PIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTP 577
           P   K+  G + E          W  ME LY SGKA+ IGVSNF+ + ++ +L VA V P
Sbjct: 124 PFVSKEVNGLSLEEA--------WKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKP 175

Query: 578 AANQVECHPVWQQAK--LRDLCASKGIHFSAYSPLG--SPGTFKAFSVLEHPVVVSTAEK 745
             NQ+E  P  Q     +   C    I   AYSPLG     T +  S      V   +EK
Sbjct: 176 QVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQDDSQPFFEYVKELSEK 235

Query: 746 LGKTPAQVALRWGVQAGHSVLPKSTNEE 829
             K+ AQ+ LRW  + G  VLP +T+ +
Sbjct: 236 YIKSEAQIILRWVTKRG--VLPVTTSSK 261

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>P82125:AFR_PIG 1,5-anhydro-D-fructose reductase - Sus scrofa (Pig)|
          Length = 206

 Score = 98.6 bits (244), Expect = 5e-20
 Identities = 71/219 (32%), Positives = 99/219 (45%), Gaps = 1/219 (0%)
 Frame = +2

Query: 95  KIPSVGLGTWQSEPG-VVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTR 271
           KIP +GLGTWQ+ PG  V +AV  A+  GYRH D A +Y NE E+G  ++   DEGV  R
Sbjct: 1   KIPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRR 60

Query: 272 KDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPA 451
           +DLFI SK                      +  Y+DL  +HWP++ K G           
Sbjct: 61  EDLFIVSK----------------------KXXYLDLXNIHWPMQFKPG---------EV 89

Query: 452 DIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQAKLRD 631
           D+P   + M           I  SN   K            P  NQ+E HP   Q     
Sbjct: 90  DLPVDRSGM-----------IVASNTDFK-----------XPVTNQIESHPYLTQK--IS 125

Query: 632 LCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKL 748
              S+ +  +AY PLG  G+ +   +LE PV+ + A+++
Sbjct: 126 FXQSRNVSVTAYRPLG--GSSEGVPLLEDPVIQTXAKRI 162

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>P76234:YEAE_ECOLI Uncharacterized protein yeaE - Escherichia coli|
          Length = 284

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 79/270 (29%), Positives = 119/270 (44%), Gaps = 16/270 (5%)
 Frame = +2

Query: 98  IPSVGLGTWQ-----SEPGVVGDAVYAAVKAGYRHIDCAQVY---GNEKEIGFALKKVFD 253
           +P+VG GTW      S+      A+ A ++ G   ID A++Y   G EK +G AL  +  
Sbjct: 14  LPAVGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGL-- 71

Query: 254 EGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 433
                R+ +F+ SK++  N   +    A + +L+ L TDY+DLYL+HW         F  
Sbjct: 72  -----REKVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHW------SGSFAF 120

Query: 434 ENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQ 613
           E  +        AAME L   GK R  GVSN     ++EL  +    P  NQ   + V  
Sbjct: 121 EETV--------AAMEKLIAQGKIRRWGVSNLDYADMQELWQL----PGGNQCATNQVLY 168

Query: 614 QAKLRDL-------CASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPAQVA 772
               R +       C  + +   AYSPL   G  +   +L++ VV   A     + AQV 
Sbjct: 169 HLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRN-GLLKNAVVNEIAHAHNISAAQVL 227

Query: 773 LRWGV-QAGHSVLPKSTNEERIRANIDVYD 859
           L W +   G   +PK+     ++ N  V +
Sbjct: 228 LAWVISHQGVMAIPKAATIAHVQQNAAVLE 257

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>P80874:GS69_BACSU General stress protein 69 - Bacillus subtilis|
          Length = 331

 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 58/177 (32%), Positives = 88/177 (49%), Gaps = 14/177 (7%)
 Frame = +2

Query: 77  VLNTGAKIPSVGLGTWQSEPGVVG--------DAVYAAVKAGYRHIDCAQVYG---NEKE 223
           + +TG +   +GLGTW     + G        + + AA+  G   ID A  YG   +E+ 
Sbjct: 6   IADTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEI 65

Query: 224 IGFALKKVF--DEGVTTRKDLFITSKLWCTNHAPED-VPVALDGTLQDLQTDYVDLYLVH 394
           +G A+K+    D+ +   K            HA    +   ++ +L+ LQTDY+DLY VH
Sbjct: 66  VGKAIKEYGKRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLYQVH 125

Query: 395 WPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVA 565
           WP           + ++P  I  T   M+ LYD+GK RAIGVSNFS ++++   AVA
Sbjct: 126 WP-----------DPLVP--IEETAEVMKELYDAGKIRAIGVSNFSIEQMDTFRAVA 169

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>P25906:YDBC_ECOLI Putative oxidoreductase ydbC - Escherichia coli|
          Length = 286

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 72/282 (25%), Positives = 116/282 (41%), Gaps = 24/282 (8%)
 Frame = +2

Query: 74  FVLNTGAKIPSVGLGTWQ-SEPGVVGD---------AVYAAVKAGYRHIDCAQVYG---N 214
           F L T + +  +G G  Q + PGV G           +  A+  G  HID +  YG    
Sbjct: 6   FTLGTKS-VNRLGYGAMQLAGPGVFGPPRDRHVAITVLREALALGVNHIDTSDFYGPHVT 64

Query: 215 EKEIGFALKKVFDEGVTTRKDLFITSKL---------WCTNHAPEDVPVALDGTLQDLQT 367
            + I  AL    D       DL I +K+         W    +P ++  A+   L++L  
Sbjct: 65  NQIIREALYPYSD-------DLTIVTKIGARRGEDASWLPAFSPAELQKAVHDNLRNLGL 117

Query: 368 DYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVE 547
           D +D+      +R+  G G  P       I A+   +  +   G  + IG+SN +  +V 
Sbjct: 118 DVLDVV----NLRVMMGDGHGPAE---GSIEASLTVLAEMQQQGLVKHIGLSNVTPTQVA 170

Query: 548 ELLAVARVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVV 727
           E   +A +    N+         A + D  A  GI +  + PLG       F+ L+   +
Sbjct: 171 EARKIAEIVCVQNEYNIAHRADDAMI-DALAHDGIAYVPFFPLGG------FTPLQSSTL 223

Query: 728 VSTAEKLGKTPAQVALRWGVQAGHSVL--PKSTNEERIRANI 847
              A  LG TP QVAL W +Q   ++L  P +++   +R N+
Sbjct: 224 SDVAASLGATPMQVALAWLLQRSPNILLIPGTSSVAHLRENM 265

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>Q9PWR1:KCAB1_CHICK Voltage-gated potassium channel subunit beta-1 - Gallus gallus|
           (Chicken)
          Length = 401

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 83/323 (25%), Positives = 133/323 (41%), Gaps = 54/323 (16%)
 Frame = +2

Query: 41  SVGERQGMALHFVLNTGAKIPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQV 205
           S  ++ GM    +  +G ++  +GLGTW +  G + D V       A ++G    D A+V
Sbjct: 64  STAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAEQLMTIAYESGVNLFDTAEV 123

Query: 206 YGNEKE---IGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQ 355
           Y   K    +G  LKK   +G   R  L IT+KL+    A  +       +   L  +LQ
Sbjct: 124 YAAGKAEVILGNILKK---KG-WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLRASLQ 179

Query: 356 DLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSC 535
            LQ +YVD+   +            P+N  P +      AM  + + G A   G S +S 
Sbjct: 180 RLQLEYVDVVFAN-----------RPDNNTPME--EIVRAMTHVINQGMAMYWGTSRWSA 226

Query: 536 KKVEELLAVAR----VTPAANQVECHPVWQQAK----LRDLCASKGIHFSAYSPL----- 676
            ++ E  +VAR    + P   Q E H ++Q+ K    L +L    G+    +SPL     
Sbjct: 227 MEIMEAYSVARQFNLIPPVCEQAEYH-LFQREKVEVQLPELYHKIGVGAMTWSPLACGII 285

Query: 677 ----------GSPGTFKAFSVLEHPVVVS--------------TAEKLGKTPAQVALRWG 784
                      S    K +  L+  ++                 AE+LG T  Q+A+ W 
Sbjct: 286 SGKYGNGVPESSRAALKCYQWLKEKIISEEGRKQQTKLKDLSPIAERLGCTLPQLAVAWC 345

Query: 785 V--QAGHSVLPKSTNEERIRANI 847
           +  +   SVL  S+N E++  N+
Sbjct: 346 LRNEGVSSVLLGSSNPEQLIENL 368

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>P77256:YDJG_ECOLI Uncharacterized oxidoreductase ydjG - Escherichia coli|
          Length = 326

 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 60/224 (26%), Positives = 87/224 (38%), Gaps = 27/224 (12%)
 Frame = +2

Query: 86  TGAKIPSVGLGTWQSEPG----------VVGDAVYAAVKAGYRHIDCAQVYG---NEKEI 226
           T   +  +GLGTW    G          +  D +  A + G   ID A  Y    +E  +
Sbjct: 9   TDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIV 68

Query: 227 GFALKKVFDEGVTT----------RKDLF--ITSKLWCTNHAPEDVPVALDGTLQDLQTD 370
           G ALKK+  E V            +  LF  +  +    N +PE +   +  +LQ L  D
Sbjct: 69  GQALKKLPREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAASLQRLGID 128

Query: 371 YVDLYLVHWPIRMKKGAGFNPENVIP--ADIPATWAAMESLYDSGKARAIGVSNFSCKKV 544
           Y+D+Y+ HW            ++V P    I  T A +  L   GK RAIG +N     +
Sbjct: 129 YIDIYMTHW------------QSVPPFFTPIAETVAVLNELKSEGKIRAIGAANVDADHI 176

Query: 545 EELLAVARVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPL 676
            E L    +     +        + +L  LC   GI    YSPL
Sbjct: 177 REYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPL 220

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>P63144:KCAB1_RAT Voltage-gated potassium channel subunit beta-1 - Rattus norvegicus|
           (Rat)
          Length = 401

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 79/320 (24%), Positives = 130/320 (40%), Gaps = 51/320 (15%)
 Frame = +2

Query: 41  SVGERQGMALHFVLNTGAKIPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQV 205
           S  ++ GM    +  +G ++  +GLGTW +  G + D V       A ++G    D A+V
Sbjct: 64  STAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEV 123

Query: 206 YGNEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQ 364
           Y   K     L  +  +    R  L IT+KL+    A  +       +   L G+LQ LQ
Sbjct: 124 YAAGK-AEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQ 182

Query: 365 TDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKV 544
            +YVD+   +            P++  P +      AM  + + G A   G S +S  ++
Sbjct: 183 LEYVDVVFAN-----------RPDSNTPME--EIVRAMTHVINQGMAMYWGTSRWSAMEI 229

Query: 545 EELLAVAR----VTPAANQVECHPVWQQAK----LRDLCASKGIHFSAYSPL-------- 676
            E  +VAR    + P   Q E H ++Q+ K    L +L    G+    +SPL        
Sbjct: 230 MEAYSVARQFNMIPPVCEQAEYH-LFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGK 288

Query: 677 -------GSPGTFKAFSVLEHPVVVS--------------TAEKLGKTPAQVALRWGV-- 787
                   S  + K +  L+  +V                 AE+LG T  Q+A+ W +  
Sbjct: 289 YGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRN 348

Query: 788 QAGHSVLPKSTNEERIRANI 847
           +   SVL  S+  E++  N+
Sbjct: 349 EGVSSVLLGSSTPEQLIENL 368

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>Q28528:KCAB1_MUSPU Voltage-gated potassium channel subunit beta-1 - Mustela putorius|
           (European polecat)
          Length = 408

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 79/314 (25%), Positives = 128/314 (40%), Gaps = 51/314 (16%)
 Frame = +2

Query: 59  GMALHFVLNTGAKIPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYGNEKE 223
           GMA   +  +G ++  +GLGTW +  G + D V       A ++G    D A+VY   K 
Sbjct: 77  GMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK- 135

Query: 224 IGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDL 382
               L  +  +    R  L IT+KL+    A  +       +   L G+LQ LQ +YVD+
Sbjct: 136 AEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDV 195

Query: 383 YLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAV 562
              +            P++  P +      AM  + + G A   G S +S  ++ E  +V
Sbjct: 196 VFAN-----------RPDSNTPME--EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSV 242

Query: 563 AR----VTPAANQVECHPVWQQAK----LRDLCASKGIHFSAYSPL-------------- 676
           AR    + P   Q E H ++Q+ K    L +L    G+    +SPL              
Sbjct: 243 ARQFNMIPPVCEQAEYH-LFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVP 301

Query: 677 -GSPGTFKAFSVLEHPVVVS--------------TAEKLGKTPAQVALRWGV--QAGHSV 805
             S  + K +  L+  +V                 AE+LG T  Q+A+ W +  +   SV
Sbjct: 302 ESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSV 361

Query: 806 LPKSTNEERIRANI 847
           L  S+  E++  N+
Sbjct: 362 LLGSSTPEQLIENL 375

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>P63143:KCAB1_MOUSE Voltage-gated potassium channel subunit beta-1 - Mus musculus|
           (Mouse)
          Length = 401

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 79/320 (24%), Positives = 130/320 (40%), Gaps = 51/320 (15%)
 Frame = +2

Query: 41  SVGERQGMALHFVLNTGAKIPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQV 205
           S  ++ GM    +  +G ++  +GLGTW +  G + D V       A ++G    D A+V
Sbjct: 64  STAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEV 123

Query: 206 YGNEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQ 364
           Y   K     L  +  +    R  L IT+KL+    A  +       +   L G+LQ LQ
Sbjct: 124 YAAGK-AEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQ 182

Query: 365 TDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKV 544
            +YVD+   +            P++  P +      AM  + + G A   G S +S  ++
Sbjct: 183 LEYVDVVFAN-----------RPDSNTPME--EIVRAMTHVINQGMAMYWGTSRWSAMEI 229

Query: 545 EELLAVAR----VTPAANQVECHPVWQQAK----LRDLCASKGIHFSAYSPL-------- 676
            E  +VAR    + P   Q E H ++Q+ K    L +L    G+    +SPL        
Sbjct: 230 MEAYSVARQFNMIPPVCEQAEYH-LFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGK 288

Query: 677 -------GSPGTFKAFSVLEHPVVVS--------------TAEKLGKTPAQVALRWGV-- 787
                   S  + K +  L+  +V                 AE+LG T  Q+A+ W +  
Sbjct: 289 YGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRN 348

Query: 788 QAGHSVLPKSTNEERIRANI 847
           +   SVL  S+  E++  N+
Sbjct: 349 EGVSSVLLGSSTPEQLIENL 368

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>Q4PJK1:KCAB1_BOVIN Voltage-gated potassium channel subunit beta-1 - Bos taurus|
           (Bovine)
          Length = 401

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 79/320 (24%), Positives = 130/320 (40%), Gaps = 51/320 (15%)
 Frame = +2

Query: 41  SVGERQGMALHFVLNTGAKIPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQV 205
           S  ++ GM    +  +G ++  +GLGTW +  G + D V       A ++G    D A+V
Sbjct: 64  STAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEV 123

Query: 206 YGNEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQ 364
           Y   K     L  +  +    R  L IT+KL+    A  +       +   L G+LQ LQ
Sbjct: 124 YAAGK-AEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQ 182

Query: 365 TDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKV 544
            +YVD+   +            P++  P +      AM  + + G A   G S +S  ++
Sbjct: 183 LEYVDVVFAN-----------RPDSNTPME--EIVRAMTHVINQGMAMYWGTSRWSAMEI 229

Query: 545 EELLAVAR----VTPAANQVECHPVWQQAK----LRDLCASKGIHFSAYSPL-------- 676
            E  +VAR    + P   Q E H ++Q+ K    L +L    G+    +SPL        
Sbjct: 230 MEAYSVARQFNMIPPVCEQAEYH-LFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGK 288

Query: 677 -------GSPGTFKAFSVLEHPVVVS--------------TAEKLGKTPAQVALRWGV-- 787
                   S  + K +  L+  +V                 AE+LG T  Q+A+ W +  
Sbjct: 289 YGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRN 348

Query: 788 QAGHSVLPKSTNEERIRANI 847
           +   SVL  S+  E++  N+
Sbjct: 349 EGVSSVLLGSSTPEQLIENL 368

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>Q94A68:Y1669_ARATH Putative oxidoreductase At1g06690, chloroplast precursor -|
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 377

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 63/269 (23%), Positives = 107/269 (39%), Gaps = 38/269 (14%)
 Frame = +2

Query: 176 GYRHIDCAQVYGNEKEIG-FALKKVFDEGVTTRKDLFITSKLWCTNH--------APEDV 328
           G    D A+VYG++  +G  + + +    +  RK+ +  +++               E V
Sbjct: 98  GIDFFDTAEVYGSKFSLGAISSETLLGRFIRERKERYPGAEVSVATKFAALPWRFGRESV 157

Query: 329 PVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKAR 508
             AL  +L  L+   VDLY +HWP     G   N   +           +    + G  +
Sbjct: 158 VTALKDSLSRLELSSVDLYQLHWP-----GLWGNEGYL---------DGLGDAVEQGLVK 203

Query: 509 AIGVSNFSCKKVE---ELLAVARVTPAANQVECHPVW---QQAKLRDLCASKGIHFSAYS 670
           A+GVSN+S K++    E L    +  A+NQV    ++   +Q  ++  C   G+   AYS
Sbjct: 204 AVGVSNYSEKRLRDAYERLKKRGIPLASNQVNYSLIYRAPEQTGVKAACDELGVTLIAYS 263

Query: 671 PLGSPGTFKAFSVLEHPV----------------------VVSTAEKLGKTPAQVALRWG 784
           P+ + G        E+P                       +    E   KTP Q+AL W 
Sbjct: 264 PI-AQGALTGKYTPENPPSGPRGRIYTREFLTKLQPLLNRIKQIGENYSKTPTQIALNWL 322

Query: 785 VQAGHSV-LPKSTNEERIRANIDVYDWSI 868
           V  G+ + +P + N E+ +       WS+
Sbjct: 323 VAQGNVIPIPGAKNAEQAKEFAGAIGWSL 351

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>Q9XT31:KCAB1_RABIT Voltage-gated potassium channel subunit beta-1 - Oryctolagus|
           cuniculus (Rabbit)
          Length = 419

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 78/314 (24%), Positives = 127/314 (40%), Gaps = 51/314 (16%)
 Frame = +2

Query: 59  GMALHFVLNTGAKIPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYGNEKE 223
           GM    +  +G ++  +GLGTW +  G + D V       A ++G    D A+VY   K 
Sbjct: 88  GMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK- 146

Query: 224 IGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDL 382
               L  +  +    R  L IT+KL+    A  +       +   L G+LQ LQ +YVD+
Sbjct: 147 AEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDV 206

Query: 383 YLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAV 562
              +            P++  P +      AM  + + G A   G S +S  ++ E  +V
Sbjct: 207 VFAN-----------RPDSNTPME--EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSV 253

Query: 563 AR----VTPAANQVECHPVWQQAK----LRDLCASKGIHFSAYSPL-------------- 676
           AR    + P   Q E H ++Q+ K    L +L    G+    +SPL              
Sbjct: 254 ARQFNMIPPVCEQAEYH-LFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVP 312

Query: 677 -GSPGTFKAFSVLEHPVVVS--------------TAEKLGKTPAQVALRWGV--QAGHSV 805
             S  + K +  L+  +V                 AE+LG T  Q+A+ W +  +   SV
Sbjct: 313 ESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSV 372

Query: 806 LPKSTNEERIRANI 847
           L  S+  E++  N+
Sbjct: 373 LLGSSTPEQLIENL 386

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>Q14722:KCAB1_HUMAN Voltage-gated potassium channel subunit beta-1 - Homo sapiens|
           (Human)
          Length = 419

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 78/314 (24%), Positives = 127/314 (40%), Gaps = 51/314 (16%)
 Frame = +2

Query: 59  GMALHFVLNTGAKIPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYGNEKE 223
           GM    +  +G ++  +GLGTW +  G + D V       A ++G    D A+VY   K 
Sbjct: 88  GMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK- 146

Query: 224 IGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDL 382
               L  +  +    R  L IT+KL+    A  +       +   L G+LQ LQ +YVD+
Sbjct: 147 AEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDV 206

Query: 383 YLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAV 562
              +            P++  P +      AM  + + G A   G S +S  ++ E  +V
Sbjct: 207 VFAN-----------RPDSNTPME--EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSV 253

Query: 563 AR----VTPAANQVECHPVWQQAK----LRDLCASKGIHFSAYSPL-------------- 676
           AR    + P   Q E H ++Q+ K    L +L    G+    +SPL              
Sbjct: 254 ARQFNMIPPVCEQAEYH-LFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVP 312

Query: 677 -GSPGTFKAFSVLEHPVVVS--------------TAEKLGKTPAQVALRWGV--QAGHSV 805
             S  + K +  L+  +V                 AE+LG T  Q+A+ W +  +   SV
Sbjct: 313 ESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSV 372

Query: 806 LPKSTNEERIRANI 847
           L  S+  E++  N+
Sbjct: 373 LLGSSTPEQLIENL 386

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>P46905:YCCK_BACSU Uncharacterized oxidoreductase yccK - Bacillus subtilis|
          Length = 310

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 71/287 (24%), Positives = 116/287 (40%), Gaps = 36/287 (12%)
 Frame = +2

Query: 149 DAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPEDV 328
           D V  A+  G   ID A +YG  +      + V + GV  R +L I +K     H   D 
Sbjct: 40  DLVRTALDGGVNFIDTAFIYGLGRSEELIGEVVQERGV--RNELIIATK---GAHKEVDG 94

Query: 329 PVALDGT-----------LQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAA 475
            + LD +           L+ L+TDY+DLY VH+P       G  P     A++  T   
Sbjct: 95  SIELDNSREFLRSEVEKSLKRLKTDYIDLYYVHFP------DGKTP----LAEVAGT--- 141

Query: 476 MESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQAKLRDLCASKGIH 655
           ++ L D GK +AIG SN   +++++  A   +     +        + +L   C  +GI 
Sbjct: 142 LKELKDEGKIKAIGASNLDYQQLQDFNADGYLEVFQAEYSLIQRDAEKELLPYCEKQGIS 201

Query: 656 FSAYSPLGS---PGTFKAFSVLEH--------------------PVVVSTAEKLGKTPAQ 766
           F  Y PL S    G F   +V +                       + + AE+     A 
Sbjct: 202 FIPYFPLASGLLTGKFTQDTVFDDFRKDKPQFQGETFIHNLKKVDKLKAVAEEKQADTAH 261

Query: 767 VALRWGV--QAGHSVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEI 901
           VAL W +   A  +++P +   E+++ N+   +  +  D     S+I
Sbjct: 262 VALAWLLTRPAIDAIIPGAKRPEQLQDNLKTLNIELTEDEVNFISDI 308

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>P46336:IOLS_BACSU Protein iolS - Bacillus subtilis|
          Length = 310

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 40/145 (27%), Positives = 75/145 (51%), Gaps = 11/145 (7%)
 Frame = +2

Query: 149 DAVYAAVKAGYRHIDCAQVYG---NEKEIGFALKKVFDEGVTTRKDLFITSKL------- 298
           + V  A++ G   +D A +YG   +E+ IG  L++        R+D+ I +K        
Sbjct: 39  ELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLREF------NREDVVIATKAAHRKQGN 92

Query: 299 -WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAA 475
            +  +++P+ +  ++D +L+ L TDY+DL+ +H+           P+   P D      A
Sbjct: 93  DFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHF-----------PDEHTPKDEAVN--A 139

Query: 476 MESLYDSGKARAIGVSNFSCKKVEE 550
           +  +  +GK R+IGVSNFS ++++E
Sbjct: 140 LNEMKKAGKIRSIGVSNFSLEQLKE 164

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>P76187:YDHF_ECOLI Oxidoreductase ydhF - Escherichia coli|
          Length = 298

 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 68/248 (27%), Positives = 101/248 (40%), Gaps = 23/248 (9%)
 Frame = +2

Query: 176 GYRHIDCAQVYGNEKEIGFALKKVFDEGVTT----RKDLFITSKLWCTNHAPEDVPV--- 334
           G   +D A +YG     G+  +  F E +      R+ + I SK      A E+  +   
Sbjct: 45  GVTTVDHADIYG-----GYQCEAAFGEALKLAPHLRERMEIVSKCGIATTAREENVIGHY 99

Query: 335 ---------ALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESL 487
                    + + +L +L TD++DL L+H            P+ ++ AD  A   A + L
Sbjct: 100 ITDRDHIIKSAEQSLINLATDHLDLLLIH-----------RPDPLMDADEVAD--AFKHL 146

Query: 488 YDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQAKL---RDLCASKGIHF 658
           + SGK R  GVSNF+  +   L +    T A NQVE  PV Q   L    D      +  
Sbjct: 147 HQSGKVRHFGVSNFTPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRVRP 206

Query: 659 SAYSPLGSPGTFK--AFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAGHSVLP--KSTNE 826
            A+S LG    F    F  L   + V   E    +  QV   W ++     LP   S   
Sbjct: 207 MAWSCLGGGRLFNDDYFQPLRDELAVVAEELNAGSIEQVVYAWVLRLPSQPLPIIGSGKI 266

Query: 827 ERIRANID 850
           ER+RA ++
Sbjct: 267 ERVRAAVE 274

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>P63485:Y2320_MYCBO Uncharacterized oxidoreductase Mb2320 - Mycobacterium bovis|
          Length = 323

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 77/299 (25%), Positives = 114/299 (38%), Gaps = 44/299 (14%)
 Frame = +2

Query: 95  KIPSVGLGTWQS-----------EPGVVGDAVYAAVKAGYRHIDCAQVYG---NEKEIGF 232
           ++  +GLGTWQ              G   D V  A   G    D A++YG   +E+ +G 
Sbjct: 11  QVSRIGLGTWQFGSREWGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLGKSERILGE 70

Query: 233 ALKKVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 412
           AL          R ++ + SK++     P  +      + + LQ + + LY +H P    
Sbjct: 71  ALGD-------DRTEVVVASKVFPVAPFPAVIKNRERASARRLQLNRIPLYQIHQP---- 119

Query: 413 KGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQV 592
                NP  V+P  +      M  L DSG   A GVSN+S  +  +  A       +NQV
Sbjct: 120 -----NP--VVPDSV--IMPGMRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQV 170

Query: 593 E---CHPVWQQAKLRDLCASKGIH---FSAYSPLGS------------PGTFKAFSVLEH 718
                HP      L DL     +      AYSPL              PG  +A + L  
Sbjct: 171 HFSLAHP----DALEDLVPFAELENRIVIAYSPLAQGLLGGKYGLENRPGGVRALNPLFG 226

Query: 719 PVVVSTAEKLGKT-----------PAQVALRWGVQ-AGHSVLPKSTNEERIRANIDVYD 859
              +   E L  T           PAQVAL W +   G   +P +++ E++  N+   D
Sbjct: 227 TENLRRIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNVAAAD 285

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>P63484:Y2298_MYCTU Uncharacterized oxidoreductase Rv2298/MT2355 - Mycobacterium|
           tuberculosis
          Length = 323

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 77/299 (25%), Positives = 114/299 (38%), Gaps = 44/299 (14%)
 Frame = +2

Query: 95  KIPSVGLGTWQS-----------EPGVVGDAVYAAVKAGYRHIDCAQVYG---NEKEIGF 232
           ++  +GLGTWQ              G   D V  A   G    D A++YG   +E+ +G 
Sbjct: 11  QVSRIGLGTWQFGSREWGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLGKSERILGE 70

Query: 233 ALKKVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 412
           AL          R ++ + SK++     P  +      + + LQ + + LY +H P    
Sbjct: 71  ALGD-------DRTEVVVASKVFPVAPFPAVIKNRERASARRLQLNRIPLYQIHQP---- 119

Query: 413 KGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQV 592
                NP  V+P  +      M  L DSG   A GVSN+S  +  +  A       +NQV
Sbjct: 120 -----NP--VVPDSV--IMPGMRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQV 170

Query: 593 E---CHPVWQQAKLRDLCASKGIH---FSAYSPLGS------------PGTFKAFSVLEH 718
                HP      L DL     +      AYSPL              PG  +A + L  
Sbjct: 171 HFSLAHP----DALEDLVPFAELENRIVIAYSPLAQGLLGGKYGLENRPGGVRALNPLFG 226

Query: 719 PVVVSTAEKLGKT-----------PAQVALRWGVQ-AGHSVLPKSTNEERIRANIDVYD 859
              +   E L  T           PAQVAL W +   G   +P +++ E++  N+   D
Sbjct: 227 TENLRRIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNVAAAD 285

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>Q9PTM4:KCAB3_XENLA Voltage-gated potassium channel subunit beta-3 - Xenopus laevis|
           (African clawed frog)
          Length = 401

 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 76/317 (23%), Positives = 128/317 (40%), Gaps = 54/317 (17%)
 Frame = +2

Query: 59  GMALHFVLNTGAKIPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYG---N 214
           GM    +  +G ++  +GLGTW +    + D V       A + G    D A+VY     
Sbjct: 70  GMKYRNLGKSGLRVSCLGLGTWVTFGSQISDEVAENLMTVAYEHGVNLFDTAEVYAAGRA 129

Query: 215 EKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDY 373
           E+ +G  LKK        R    +T+K++    A  +       +   L G+L+ LQ DY
Sbjct: 130 ERTLGKILKK----KEWRRSSYVVTTKIYWGGQAETERGLSRKHIIEGLRGSLERLQLDY 185

Query: 374 VDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEEL 553
           VD+   +   RM   +    E ++         AM  + + G A   G S +S  ++ E 
Sbjct: 186 VDIVFAN---RMDPNSPM--EEIV--------RAMTFVINQGMAMYWGTSRWSAMEIMEA 232

Query: 554 LAVAR----VTPAANQVECHPVWQQAK----LRDLCASKGIHFSAYSPLG---------- 679
            +VAR    + P   Q E H ++Q+ K    L +L    G+    +SPL           
Sbjct: 233 YSVARQFNLIPPVCEQAEYH-LFQREKVETQLPELYHKIGVGSMTWSPLACGLITGKYTD 291

Query: 680 -----SPGTFKAFSVLEHPVVVS--------------TAEKLGKTPAQVALRWGVQAG-- 796
                S  +FK +  L+   +                 A++L  T  Q+A+ W +++   
Sbjct: 292 TVPEKSRASFKGYHWLKEKAISQEGKKQHSKVKELHPIADRLNCTVTQLAIAWCLRSEGV 351

Query: 797 HSVLPKSTNEERIRANI 847
            SVL   +N E++  N+
Sbjct: 352 SSVLLGVSNIEQLLENL 368

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>Q9PTM5:KCAB2_XENLA Voltage-gated potassium channel subunit beta-2 - Xenopus laevis|
           (African clawed frog)
          Length = 367

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 71/304 (23%), Positives = 121/304 (39%), Gaps = 50/304 (16%)
 Frame = +2

Query: 86  TGAKIPSVGLGTWQSEPGVVGD-----AVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           +G ++  +GLGTW +  G + D      +  A   G    D A+VY   K     L  + 
Sbjct: 45  SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103

Query: 251 DEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWPIRM 409
            +    R  L IT+K++    A  +       +   L  +L+ LQ DYVD+   + P   
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLDYVDVVFANRP--- 160

Query: 410 KKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVAR----VTP 577
                 +P       +  T  AM  + + G A   G S +S  ++ E  +VAR    + P
Sbjct: 161 ------DPN----TPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPP 210

Query: 578 AANQVECHPVWQ---QAKLRDLCASKGIHFSAYSPLG---------------SPGTFKAF 703
              Q E H   +   + +L +L    G+    +SPL                S  + K +
Sbjct: 211 ICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDGGIPPYSRASLKGY 270

Query: 704 SVLEHPVV--------------VSTAEKLGKTPAQVALRWGV--QAGHSVLPKSTNEERI 835
             L+  ++               + AE+LG T  Q+A+ W +  +   SVL  ++N +++
Sbjct: 271 QWLKDKILSEEGRRQQAKLKEFQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQL 330

Query: 836 RANI 847
             NI
Sbjct: 331 LENI 334

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>P62483:KCAB2_RAT Voltage-gated potassium channel subunit beta-2 - Rattus norvegicus|
           (Rat)
          Length = 367

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 71/304 (23%), Positives = 121/304 (39%), Gaps = 50/304 (16%)
 Frame = +2

Query: 86  TGAKIPSVGLGTWQSEPGVVGD-----AVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           +G ++  +GLGTW +  G + D      +  A   G    D A+VY   K     L  + 
Sbjct: 45  SGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103

Query: 251 DEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWPIRM 409
            +    R  L IT+K++    A  +       +   L  +L+ LQ +YVD+   + P   
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--- 160

Query: 410 KKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVAR----VTP 577
                 +P       +  T  AM  + + G A   G S +S  ++ E  +VAR    + P
Sbjct: 161 ------DPN----TPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPP 210

Query: 578 AANQVECHPVWQ---QAKLRDLCASKGIHFSAYSPLG---------------SPGTFKAF 703
              Q E H   +   + +L +L    G+    +SPL                S  + K +
Sbjct: 211 ICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGY 270

Query: 704 SVLEHPV--------------VVSTAEKLGKTPAQVALRWGV--QAGHSVLPKSTNEERI 835
             L+  +              + + AE+LG T  Q+A+ W +  +   SVL  ++N E++
Sbjct: 271 QWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQL 330

Query: 836 RANI 847
             NI
Sbjct: 331 MENI 334

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>P62482:KCAB2_MOUSE Voltage-gated potassium channel subunit beta-2 - Mus musculus|
           (Mouse)
          Length = 367

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 71/304 (23%), Positives = 121/304 (39%), Gaps = 50/304 (16%)
 Frame = +2

Query: 86  TGAKIPSVGLGTWQSEPGVVGD-----AVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           +G ++  +GLGTW +  G + D      +  A   G    D A+VY   K     L  + 
Sbjct: 45  SGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103

Query: 251 DEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWPIRM 409
            +    R  L IT+K++    A  +       +   L  +L+ LQ +YVD+   + P   
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--- 160

Query: 410 KKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVAR----VTP 577
                 +P       +  T  AM  + + G A   G S +S  ++ E  +VAR    + P
Sbjct: 161 ------DPN----TPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPP 210

Query: 578 AANQVECHPVWQ---QAKLRDLCASKGIHFSAYSPLG---------------SPGTFKAF 703
              Q E H   +   + +L +L    G+    +SPL                S  + K +
Sbjct: 211 ICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGY 270

Query: 704 SVLEHPV--------------VVSTAEKLGKTPAQVALRWGV--QAGHSVLPKSTNEERI 835
             L+  +              + + AE+LG T  Q+A+ W +  +   SVL  ++N E++
Sbjct: 271 QWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQL 330

Query: 836 RANI 847
             NI
Sbjct: 331 MENI 334

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>P40691:A115_TOBAC Auxin-induced protein PCNT115 - Nicotiana tabacum (Common tobacco)|
          Length = 307

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 70/284 (24%), Positives = 111/284 (39%), Gaps = 40/284 (14%)
 Frame = +2

Query: 116 GTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYG---NEKEIGFALKKVFDEGVTTRKDLFI 286
           G  + EP ++   ++ A+ +G   +D + VYG   NE  +G ALK    E V       I
Sbjct: 35  GPPKPEPDMI-QLIHHAINSGITLLDTSDVYGPHTNEILLGKALKGGTRERVVLATKFGI 93

Query: 287 T-------SKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVI 445
                         +  P  V  A + +L+ L  D +DLY  H             +  +
Sbjct: 94  VLGDEKKAEGKRAVHGDPAYVRAACEASLKRLDIDCIDLYYQH-----------RVDTRV 142

Query: 446 PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQ---Q 616
           P +I  T   ++ L + GK + IG+S  S   +    AV  +T  A Q+E   +W    +
Sbjct: 143 PIEI--TVGELKKLVEEGKLKYIGLSEASASTIRRAHAVHPIT--AVQLEWS-LWSRDVE 197

Query: 617 AKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLE-------------------------HP 721
            ++   C   GI   AYSPLG         +LE                         + 
Sbjct: 198 EEIIPTCRELGIGIVAYSPLGRGFLSSGPKLLEDMSNEDYRKYLPRFQAENLENNKNLYE 257

Query: 722 VVVSTAEKLGKTPAQVALRWGVQAGHSV--LPKSTNEERIRANI 847
            +   A + G TP+Q+AL W    G+ V  +P +T  E +  N+
Sbjct: 258 RICEMAVRKGCTPSQLALAWVHHQGNDVCPIPGTTKIENLNQNM 301

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>P42972:YCSN_BACSU Uncharacterized oxidoreductase ycsN - Bacillus subtilis|
          Length = 300

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 64/282 (22%), Positives = 108/282 (38%), Gaps = 27/282 (9%)
 Frame = +2

Query: 113 LGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT----RKDL 280
           L  W      +   +   +  G    D A +YG     G+  +K+F   +      R+++
Sbjct: 22  LNEWNYSDAELLSLIEWCIDHGITTFDHADIYG-----GYTCEKLFGNALALSPGLRENI 76

Query: 281 FITSKLWCTNHAPE--------------DVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 418
            + +K      +PE               +  +++ +L +L+TDY+D+ L+H P  +   
Sbjct: 77  ELVTKCGIVLESPERPAHRSHHYNTSKSHILASVEQSLMNLRTDYIDMLLIHRPDPL--- 133

Query: 419 AGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVEC 598
              +PE V          A ++L  SGK R  GVSNF   +   L +        NQ+E 
Sbjct: 134 --MDPEGVA--------EAFQALKCSGKVRYFGVSNFKDHQYRMLESYLPEKLVTNQIEL 183

Query: 599 HPVWQQAKL---RDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVVVSTAEKLGKTPA-- 763
                +  L    +LC  K I   A+SPL     F   +  +  V  +     G+  A  
Sbjct: 184 SAYELENMLDGTLNLCQEKRIPPMAWSPLAGGKVFTENTDKDRRVRTALESVQGEIGAAS 243

Query: 764 --QVALRWGVQAGHSVLP--KSTNEERIRANIDVYDWSIPGD 877
             +V   W       ++P   S   ERI A I+   + +  D
Sbjct: 244 LDEVMYAWLYTHPAGIMPIVGSGKRERISAAINALSYKLDQD 285

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>Q09923:YAKC_SCHPO Aldo-keto reductase yakc [NADP+] - Schizosaccharomyces pombe|
           (Fission yeast)
          Length = 340

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 66/259 (25%), Positives = 105/259 (40%), Gaps = 43/259 (16%)
 Frame = +2

Query: 164 AVKAGYRHIDCAQVYG---NEKEIGFALKKVFDEGVTTRKDLFITSKLW----------C 304
           A   G    D + +YG   NE+ IG   K+        RK++F+ +K             
Sbjct: 42  AADLGCTFWDSSDMYGFGANEECIGRWFKQT-----GRRKEIFLATKFGYEKNPETGELS 96

Query: 305 TNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMES 484
            N+ P+ +  ALD +L+ L  D +DLY VH      + +G  P       I     A++ 
Sbjct: 97  LNNEPDYIEKALDLSLKRLGIDCIDLYYVH------RFSGETP-------IEKIMGALKK 143

Query: 485 LYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQAKLRDL-----CASKG 649
             ++GK R IG+S  S   +    AV  V  +A QVE  P   + +  ++     C    
Sbjct: 144 CVEAGKIRYIGLSECSANTIRRAAAVYPV--SAVQVEYSPFSLEIERPEIGVMKACRENN 201

Query: 650 IHFSAYSPLG---------SPGTF------------KAFSVLEHPVVVSTAEKLGK---- 754
           I    Y+PLG         SP  F            +  +  ++  +V+  EK+      
Sbjct: 202 ITIVCYAPLGRGFLTGAYKSPDDFPEGDFRRKAPRYQKENFYKNLELVTKIEKIATANNI 261

Query: 755 TPAQVALRWGVQAGHSVLP 811
           TP Q++L W +  G  +LP
Sbjct: 262 TPGQLSLAWLLAQGDDILP 280

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>P0A9T5:TAS_SHIFL Protein tas - Shigella flexneri|
          Length = 346

 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 85/344 (24%), Positives = 135/344 (39%), Gaps = 62/344 (18%)
 Frame = +2

Query: 62   MALHFVLNTGAKIPSVGLGTWQ-SEPGVVGDA---VYAAVKAGYRHIDCAQVYG------ 211
            M  H + ++  ++ ++GLGT    E     DA   +  AV  G   ID A++Y       
Sbjct: 1    MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60

Query: 212  ----NEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPE------------DVPVALD 343
                 E  +G  L K       +R+ L I SK+   +   +            ++  AL 
Sbjct: 61   TQGLTETYVGNWLAKH-----GSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALH 115

Query: 344  GTLQDLQTDYVDLYLVHWPIRMKK---GAGFNPENVIPA-DIPATWAAMESLYDSGKARA 511
             +L+ LQTDY+DLY VHWP R        G++  +  PA  +  T  A+     +GK R 
Sbjct: 116  DSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRY 175

Query: 512  IGVSNFSCKKVEELLAVA------RVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYS- 670
            IGVSN +   V   L +A      R+    N         +  L ++   +G+   AYS 
Sbjct: 176  IGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSC 235

Query: 671  ---------------PLGSPGT-FKAFSVLEH-------PVVVSTAEKLGKTPAQVALRW 781
                           P G+  T F  F+              V  A + G  PAQ+AL +
Sbjct: 236  LGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAF 295

Query: 782  GVQAGH--SVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQ 907
              +     S L  +T  ++++ NI+     +  D+ A    + Q
Sbjct: 296  VRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQ 339

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>P0A9T4:TAS_ECOLI Protein tas - Escherichia coli|
          Length = 346

 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 85/344 (24%), Positives = 135/344 (39%), Gaps = 62/344 (18%)
 Frame = +2

Query: 62   MALHFVLNTGAKIPSVGLGTWQ-SEPGVVGDA---VYAAVKAGYRHIDCAQVYG------ 211
            M  H + ++  ++ ++GLGT    E     DA   +  AV  G   ID A++Y       
Sbjct: 1    MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60

Query: 212  ----NEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPE------------DVPVALD 343
                 E  +G  L K       +R+ L I SK+   +   +            ++  AL 
Sbjct: 61   TQGLTETYVGNWLAKH-----GSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALH 115

Query: 344  GTLQDLQTDYVDLYLVHWPIRMKK---GAGFNPENVIPA-DIPATWAAMESLYDSGKARA 511
             +L+ LQTDY+DLY VHWP R        G++  +  PA  +  T  A+     +GK R 
Sbjct: 116  DSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRY 175

Query: 512  IGVSNFSCKKVEELLAVA------RVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYS- 670
            IGVSN +   V   L +A      R+    N         +  L ++   +G+   AYS 
Sbjct: 176  IGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSC 235

Query: 671  ---------------PLGSPGT-FKAFSVLEH-------PVVVSTAEKLGKTPAQVALRW 781
                           P G+  T F  F+              V  A + G  PAQ+AL +
Sbjct: 236  LGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAF 295

Query: 782  GVQAGH--SVLPKSTNEERIRANIDVYDWSIPGDLFAGFSEIEQ 907
              +     S L  +T  ++++ NI+     +  D+ A    + Q
Sbjct: 296  VRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQ 339

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>Q13303:KCAB2_HUMAN Voltage-gated potassium channel subunit beta-2 - Homo sapiens|
           (Human)
          Length = 367

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 70/304 (23%), Positives = 120/304 (39%), Gaps = 50/304 (16%)
 Frame = +2

Query: 86  TGAKIPSVGLGTWQSEPGVVGD-----AVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           +G ++  +GLGTW +  G + D      +  A   G    D A+VY   K     L  + 
Sbjct: 45  SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103

Query: 251 DEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWPIRM 409
            +    R  L IT+K++    A  +       +   L  +L+ LQ +YVD+   + P   
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--- 160

Query: 410 KKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVAR----VTP 577
                 +P       +  T  AM  + + G A   G S +S  ++ E  +VAR      P
Sbjct: 161 ------DPN----TPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPP 210

Query: 578 AANQVECHPVWQ---QAKLRDLCASKGIHFSAYSPLG---------------SPGTFKAF 703
              Q E H   +   + +L +L    G+    +SPL                S  + K +
Sbjct: 211 ICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGY 270

Query: 704 SVLEHPV--------------VVSTAEKLGKTPAQVALRWGV--QAGHSVLPKSTNEERI 835
             L+  +              + + AE+LG T  Q+A+ W +  +   SVL  ++N +++
Sbjct: 271 QWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQL 330

Query: 836 RANI 847
             NI
Sbjct: 331 MENI 334

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>P49249:IN22_MAIZE IN2-2 protein - Zea mays (Maize)|
          Length = 306

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 54/183 (29%), Positives = 82/183 (44%), Gaps = 8/183 (4%)
 Frame = +2

Query: 155 VYAAVKAGYRHIDCAQVYG---NEKEIGFALKKVFDEGV--TTRKDLFITSKLWCTNHAP 319
           ++ AV AG   +D + VYG   NE  +G AL+    E V   T+  +         +  P
Sbjct: 47  IHHAVDAGVTFLDTSDVYGPHTNEVLLGKALQGGVREKVELATKFGVSFADGKREIHGDP 106

Query: 320 EDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSG 499
             V  A +G+ + L  D +DLY  H   R+ K         +P ++  T   ++ L + G
Sbjct: 107 AYVRTACEGSFKRLGVDCIDLYYQH---RIDKR--------VPIEV--TIGELKKLVEEG 153

Query: 500 KARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQAKLRDL---CASKGIHFSAYS 670
           K + IG+S  S   +    AV  +T  A Q+E   +W +    D+   C   GI   AYS
Sbjct: 154 KIKYIGLSEASASTIRRAHAVHPIT--AVQLEWS-LWSRDAEEDIIPTCRELGIGIVAYS 210

Query: 671 PLG 679
           PLG
Sbjct: 211 PLG 213

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>Q27955:KCAB2_BOVIN Voltage-gated potassium channel subunit beta-2 - Bos taurus|
           (Bovine)
          Length = 367

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 69/304 (22%), Positives = 121/304 (39%), Gaps = 50/304 (16%)
 Frame = +2

Query: 86  TGAKIPSVGLGTWQSEPGVVGD-----AVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           +G ++  +GLGTW +  G + D      +  A   G    D A+VY   K     L  + 
Sbjct: 45  SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNII 103

Query: 251 DEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWPIRM 409
            +    R  L IT+K++    A  +       +   L  +L+ LQ +YVD+   + P   
Sbjct: 104 KKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP--- 160

Query: 410 KKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVAR----VTP 577
                 +P       +  T  AM  + + G A   G S +S  ++ E  +VAR    + P
Sbjct: 161 ------DPN----TPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPP 210

Query: 578 AANQVECHPVWQ---QAKLRDLCASKGIHFSAYSPLG---------------SPGTFKAF 703
              Q E H   +   + +L +L    G+    +SPL                S  + K +
Sbjct: 211 ICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGY 270

Query: 704 SVLEHPV--------------VVSTAEKLGKTPAQVALRWGV--QAGHSVLPKSTNEERI 835
             L+  +              + + AE+LG T  Q+A+ W +  +   SVL  +++ +++
Sbjct: 271 QWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASSADQL 330

Query: 836 RANI 847
             NI
Sbjct: 331 MENI 334

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>Q40648:KCAB_ORYSJ Probable voltage-gated potassium channel subunit beta - Oryza|
           sativa subsp. japonica (Rice)
          Length = 328

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 74/308 (24%), Positives = 120/308 (38%), Gaps = 50/308 (16%)
 Frame = +2

Query: 86  TGAKIPSVGLGTW-----QSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVF 250
           +G ++  +  G W     Q +       + A   AG    D A+VY N +      + + 
Sbjct: 9   SGLRVSQLSYGAWVTFGNQLDVKEAKALLQACRDAGVNFFDNAEVYANGRAEEIMGQAMR 68

Query: 251 DEGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWPIRM 409
           D G   R D+ +++KL+     P D       +   L G+L+ L  DYVD+   H     
Sbjct: 69  DLG-WRRSDVVVSTKLFWGGQGPNDKGLSRKHIVEGLRGSLKRLDMDYVDVVYCH----- 122

Query: 410 KKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVAR----VTP 577
                  P+   P  +  T  AM  + D G A   G S +S +++ E  +VA     V P
Sbjct: 123 ------RPDATTP--VEETVRAMNWVIDHGMAFYWGTSEWSAQQITEAWSVANRLDLVGP 174

Query: 578 AANQVEC-----HPVWQQAKLRDLCASKGIHFSAYSPLGS--------PGTFKAFS---- 706
              Q E      H V  +++   L ++ G+  + +SPL S         G   A S    
Sbjct: 175 IVEQPEYNLFSRHKV--ESEFLPLYSTYGLGLTTWSPLASGVLTGKYAKGNIPADSRFAL 232

Query: 707 -----VLEHPVVVST----------AEKLGKTPAQVALRWGVQAGH--SVLPKSTNEERI 835
                +    +V  T          A +LG + AQ+A+ W     +  SV+  +T E +I
Sbjct: 233 ENYKNLANRSLVDDTLRKVNGLKPIASELGVSLAQLAIAWCASNPNVSSVITGATKENQI 292

Query: 836 RANIDVYD 859
             N+   D
Sbjct: 293 VENMKALD 300

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>Q63494:KCAB3_RAT Voltage-gated potassium channel subunit beta-3 - Rattus norvegicus|
           (Rat)
          Length = 404

 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 72/306 (23%), Positives = 116/306 (37%), Gaps = 52/306 (16%)
 Frame = +2

Query: 20  PSARALASVGERQGMALHFVLNTGAKIPSVGLGTW-----QSEPGVVGDAVYAAVKAGYR 184
           P+     S G   GM    +  +G ++  +GLGTW     Q       D +  A + G  
Sbjct: 64  PAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDLLTVAYEHGVN 123

Query: 185 HIDCAQVYG---NEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VPV 334
             D A+VY     E+ +G  LK    +G   R    IT+K++    A  +       +  
Sbjct: 124 LFDTAEVYAAGKAERTLGNILK---SKG-WRRSSYVITTKIFWGGQAETERGLSRKHIIE 179

Query: 335 ALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAI 514
            L G+L  LQ +YVD+   +     +       E ++         AM  + + G A   
Sbjct: 180 GLQGSLDRLQLEYVDIVFAN-----RSDPSSPMEEIV--------RAMTYVINQGLALYW 226

Query: 515 GVSNFSCKKVEELLAVAR----VTPAANQVECHPVWQQAK----LRDLCASKGIHFSAYS 670
           G S +S  ++ E  ++AR    + P   Q E H  +Q+ K    L +L    G+    +S
Sbjct: 227 GTSRWSAAEIMEAYSMARQFNLIPPVCEQAENH-FFQREKVEMQLPELYHKIGVGSVTWS 285

Query: 671 PL---------------GSPGTFKAFSVLEHPV--------------VVSTAEKLGKTPA 763
           PL                   T K +  L+  V              ++  A +LG T A
Sbjct: 286 PLACSLITSKYDGQVPDACKATVKGYQWLKEKVQSEDGKKQQARVTDLLPIAHQLGCTVA 345

Query: 764 QVALRW 781
           Q+A+ W
Sbjct: 346 QLAIAW 351

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>O43448:KCAB3_HUMAN Voltage-gated potassium channel subunit beta-3 - Homo sapiens|
           (Human)
          Length = 404

 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 71/306 (23%), Positives = 116/306 (37%), Gaps = 52/306 (16%)
 Frame = +2

Query: 20  PSARALASVGERQGMALHFVLNTGAKIPSVGLGTW-----QSEPGVVGDAVYAAVKAGYR 184
           P+     S G   GM    +  +G ++  +GLGTW     Q       D +  A + G  
Sbjct: 64  PAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVN 123

Query: 185 HIDCAQVYG---NEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VPV 334
             D A+VY     E+ +G  LK    +G   R    IT+K++    A  +       +  
Sbjct: 124 LFDTAEVYAAGKAERTLGNILK---SKG-WRRSSYVITTKIFWGGQAETERGLSRKHIIE 179

Query: 335 ALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAI 514
            L G+L+ LQ  YVD+   +     +       E ++         AM  + + G A   
Sbjct: 180 GLRGSLERLQLGYVDIVFAN-----RSDPNCPMEEIV--------RAMTYVINQGLALYW 226

Query: 515 GVSNFSCKKVEELLAVAR----VTPAANQVECHPVWQQAK----LRDLCASKGIHFSAYS 670
           G S +   ++ E  ++AR    + P   Q E H ++Q+ K    L +L    G+    + 
Sbjct: 227 GTSRWGAAEIMEAYSMARQFNLIPPVCEQAE-HHLFQREKVEMQLPELYHKIGVGSVTWY 285

Query: 671 PLGS-----------PGT----FKAFSVLEHPV--------------VVSTAEKLGKTPA 763
           PL             P T     K +  L+  V              ++  A +LG T A
Sbjct: 286 PLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGCTVA 345

Query: 764 QVALRW 781
           Q+A+ W
Sbjct: 346 QLAIAW 351

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>P77735:YAJO_ECOLI Uncharacterized oxidoreductase yajO - Escherichia coli|
          Length = 324

 Score = 42.7 bits (99), Expect = 0.003
 Identities = 58/269 (21%), Positives = 97/269 (36%), Gaps = 42/269 (15%)
 Frame = +2

Query: 101 PSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGN---EKEIGFALKKVFDEGVTTR 271
           P  G   W          +  A++ G    D A  Y +   E+ +G AL+         R
Sbjct: 26  PDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDF-----ARR 80

Query: 272 KDLFITSKLWCTNHAPEDVPVAL---------DGTLQDLQTDYVDLYLVH-WPIRMKKGA 421
           +D+ + +K++   H   D+P  L         D +L+ L  DYVD+  +H W        
Sbjct: 81  EDVVVATKVF---HRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYN----- 132

Query: 422 GFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECH 601
                      I  T  A+  +  +GKAR IG S+    +  + L + +    A  V   
Sbjct: 133 ---------TPIEETLEALNDVVKAGKARYIGASSMHASQFAQALELQKQHGWAQFVSMQ 183

Query: 602 PVW------QQAKLRDLCASKGIHFSAYSPLGSPGTFKAFSVLEHPVV------------ 727
             +      ++ ++  LC  +G+    +SPL      + +      +V            
Sbjct: 184 DHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLYKES 243

Query: 728 -----------VSTAEKLGKTPAQVALRW 781
                         +E+LG T AQVAL W
Sbjct: 244 DENDAQIAERLTGVSEELGATRAQVALAW 272

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>Q8CG76:ARK72_MOUSE Aflatoxin B1 aldehyde reductase member 2 - Mus musculus (Mouse)|
          Length = 367

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 51/204 (25%), Positives = 86/204 (42%), Gaps = 12/204 (5%)
 Frame = +2

Query: 101 PSVGLGTWQSEPGVVGDAVYAAVKA----GYRHIDCAQVY--GNEKEIGFALKKVFDEGV 262
           P+  LGT +    +   A  A+V+A    G+  +D A +Y  G  + I   L      G 
Sbjct: 46  PATVLGTMEMGRRMDASASAASVRAFLERGHSELDTAFMYCDGQSENILGGLGLGLGSGD 105

Query: 263 TTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENV 442
            T K     +     +  P+ V   L+ +L+ LQ   VDL+ +H            P++ 
Sbjct: 106 CTVKIATKANPWEGKSLKPDSVRSQLETSLKRLQCPRVDLFYLH-----------APDHS 154

Query: 443 IPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVAR----VTPAANQVECHPVW 610
            P  +  T  A   L+  GK   +G+SN++  +V E+  + +    + P   Q   +   
Sbjct: 155 TP--VEETLRACHQLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATT 212

Query: 611 QQ--AKLRDLCASKGIHFSAYSPL 676
           +Q  A+L       G+ F AY+PL
Sbjct: 213 RQVEAELLPCLRHFGLRFYAYNPL 236

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>P40690:ALKE_BABBO Aldo-keto reductase - Babesia bovis|
          Length = 285

 Score = 41.6 bits (96), Expect = 0.007
 Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 22/141 (15%)
 Frame = +2

Query: 320 EDVPVALDGTLQDLQTDYVDLYLVHWPIR---MKKGAGFN----------PENVIPADIP 460
           +++  A+DG+L  L TDY+DL  +HWP R   M     F+           EN +P +  
Sbjct: 29  DNILKAVDGSLSRLNTDYIDLLQLHWPDRYVPMNANGDFHEVFHDTENMIDENSVPLEDQ 88

Query: 461 ATWAAMESLYDSGKARAIGVSN---FSCKKVEELLAVARV-TPAANQVECHPVWQ---QA 619
               A+++L   GK R  G+SN   +   +  +L   A V  PA+ Q+  + + +   + 
Sbjct: 89  LD--ALQTLLTQGKIRHWGLSNETPWGTLRFYKLAKQAGVAAPASVQLHYNLLCRNEVEK 146

Query: 620 KLRDLC--ASKGIHFSAYSPL 676
              +LC   + GI   AY+PL
Sbjct: 147 GFVELCRPQNTGIAILAYAPL 167

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>P82810:MORA_RABIT Morphine 6-dehydrogenase - Oryctolagus cuniculus (Rabbit)|
          Length = 125

 Score = 40.8 bits (94), Expect = 0.011
 Identities = 37/111 (33%), Positives = 49/111 (44%)
 Frame = +2

Query: 506 RAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYSPLGSP 685
           ++IGVSNF+ K+V             NQVE HP   Q        SK I   AYS LGS 
Sbjct: 40  KSIGVSNFNHKRVX------------NQVEXHPYLNQ--------SKDIVLVAYSALGS- 78

Query: 686 GTFKAFSVLEHPVVVSTAEKLGKTPAQVALRWGVQAGHSVLPKSTNEERIR 838
                           + +   ++PA +ALR+ +Q G  VL KS  E  I+
Sbjct: 79  ----------------SRDPWKQSPALIALRYQLQRGVVVLAKSFIEREIK 113

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>Q46851:YGHZ_ECOLI Uncharacterized protein yghZ - Escherichia coli|
          Length = 346

 Score = 40.4 bits (93), Expect = 0.015
 Identities = 55/234 (23%), Positives = 103/234 (44%), Gaps = 25/234 (10%)
 Frame = +2

Query: 50  ERQG-MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAV-----KAGYRHIDCAQVYG 211
           ER G M   +   +G ++P++ LG W +   V       A+       G  H D A  YG
Sbjct: 8   ERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYG 67

Query: 212 N-----EKEIGFALKKVFDEGVTTRKDLFITSK----LWC----TNHAPEDVPVALDGTL 352
                 E+  G  L++ F      R +L I++K    +W     +  + + +  +LD +L
Sbjct: 68  PPPGSAEENFGRLLREDF---AAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSL 124

Query: 353 QDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFS 532
           + +  +YVD++  H   R+ +             +  T +A+     SGKA  +G+S++S
Sbjct: 125 KRMGLEYVDIFYSH---RVDENT----------PMEETASALAHAVQSGKALYVGISSYS 171

Query: 533 ---CKKVEELLAVARVTPAANQVECHPV--W-QQAKLRDLCASKGIHFSAYSPL 676
               +K+ ELL   ++    +Q   + +  W  ++ L D   + G+   A++PL
Sbjct: 172 PERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPL 225

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>Q8X529:YGHZ_ECO57 Uncharacterized protein yghZ - Escherichia coli O157:H7|
          Length = 346

 Score = 40.0 bits (92), Expect = 0.019
 Identities = 55/234 (23%), Positives = 103/234 (44%), Gaps = 25/234 (10%)
 Frame = +2

Query: 50  ERQG-MALHFVLNTGAKIPSVGLGTWQSEPGVVGDAVYAAV-----KAGYRHIDCAQVYG 211
           ER G M   +   +G ++P++ LG W +   V       A+       G  H D A  YG
Sbjct: 8   ERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYG 67

Query: 212 N-----EKEIGFALKKVFDEGVTTRKDLFITSK----LWC----TNHAPEDVPVALDGTL 352
                 E+  G  L++ F      R +L I++K    +W     +  + + +  +LD +L
Sbjct: 68  PPPGSAEENFGRLLREDF---AAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSL 124

Query: 353 QDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFS 532
           + +  +YVD++  H   R+ +             +  T +A+     SGKA  +G+S++S
Sbjct: 125 KRMGLEYVDIFYSH---RVDENT----------PMEETASALAHAVQSGKALYVGISSYS 171

Query: 533 ---CKKVEELLAVARVTPAANQVECHPV--W-QQAKLRDLCASKGIHFSAYSPL 676
               +K+ ELL   ++    +Q   + +  W  ++ L D   + G+   A++PL
Sbjct: 172 PERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPL 225

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>P38918:ARK73_RAT Aflatoxin B1 aldehyde reductase member 3 - Rattus norvegicus (Rat)|
          Length = 327

 Score = 40.0 bits (92), Expect = 0.019
 Identities = 45/187 (24%), Positives = 81/187 (43%), Gaps = 12/187 (6%)
 Frame = +2

Query: 152 AVYAAVKAGYRHIDCAQVYGNEK------EIGFALKKVFDEGVTTRKDLFITSKLWCTNH 313
           +V A ++ G+  ID A VY N +      ++G  L +   +     K     + ++    
Sbjct: 27  SVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCKVKIATK----AAPMFGKTL 82

Query: 314 APEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYD 493
            P DV   L+ +L+ LQ   VDL+ +H+           P++  P  I  T  A   L+ 
Sbjct: 83  KPADVRFQLETSLKRLQCPRVDLFYLHF-----------PDHGTP--IEETLQACHQLHQ 129

Query: 494 SGKARAIGVSNFSCKKVEELLAVAR----VTPAANQVECHPVWQQ--AKLRDLCASKGIH 655
            GK   +G+SN+   +V E+  + +    + P   Q   + + +Q   +L       G+ 
Sbjct: 130 EGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETELFPCLRHFGLR 189

Query: 656 FSAYSPL 676
           F A++PL
Sbjct: 190 FYAFNPL 196

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>Q8CG45:ARK72_RAT Aflatoxin B1 aldehyde reductase member 2 - Rattus norvegicus (Rat)|
          Length = 367

 Score = 40.0 bits (92), Expect = 0.019
 Identities = 51/204 (25%), Positives = 85/204 (41%), Gaps = 12/204 (5%)
 Frame = +2

Query: 101 PSVGLGTWQSEPGVVGDAVYAAVKA----GYRHIDCAQVY--GNEKEIGFALKKVFDEGV 262
           P   LGT +    +   A  A V+A    G   +D A +Y  G  + I  +L      G 
Sbjct: 46  PGTVLGTMEMGRRMDASASAATVRAFLERGLNELDTAFMYCDGQSESILGSLGLGLGSGD 105

Query: 263 TTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENV 442
            T K     +     +  P+ V   L+ +L+ LQ   VDL+ +H            P++ 
Sbjct: 106 CTVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPRVDLFYLH-----------APDHG 154

Query: 443 IPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVAR----VTPAANQVECHPVW 610
            P  I  T  A + L+  GK   +G+SN++  +V E+  + +    + P   Q   +   
Sbjct: 155 TP--IVETLQACQQLHQEGKFVELGLSNYASWEVAEIYTLCKSNGWILPTVYQGMYNATT 212

Query: 611 QQAKLRDLCASK--GIHFSAYSPL 676
           +Q +   L   +  G+ F AY+PL
Sbjct: 213 RQVETELLPCLRYFGLRFYAYNPL 236

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>P54569:YQKF_BACSU Uncharacterized oxidoreductase yqkF - Bacillus subtilis|
          Length = 306

 Score = 39.7 bits (91), Expect = 0.025
 Identities = 40/173 (23%), Positives = 70/173 (40%), Gaps = 15/173 (8%)
 Frame = +2

Query: 98  IPSVGLGTWQ--SEPGVVGDAVYAAVKAGYRHIDCAQVYG---NEKEIGFALKKVFDEGV 262
           I  VGLG     +E       +  A++ G  ++D A +Y    NE+ +G A++       
Sbjct: 13  ISEVGLGCMSLGTEKNKALSILDEAIELGINYLDTADLYDRGRNEEIVGDAIQN------ 66

Query: 263 TTRKDLFITSKL----------WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 412
             R D+ + +K           W  + +   +  A+  +L  L+TDY+DLY +H      
Sbjct: 67  -RRHDIILATKAGNRWDDGSEGWYWDPSKAYIKEAVKKSLTRLKTDYIDLYQLH------ 119

Query: 413 KGAGFNPENVIPADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARV 571
                     I  +I  T  A E L   G  R  G+S+     ++E +  + +
Sbjct: 120 -------GGTIEDNIDETIEAFEELKQEGVIRYYGISSIRPNVIKEYVKKSNI 165

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>P49261:CROB_LEPLU Rho beta-crystallin - Lepidodactylus lugubris (Mourning gecko)|
          Length = 89

 Score = 39.3 bits (90), Expect = 0.033
 Identities = 21/49 (42%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
 Frame = +2

Query: 359 LQTDYVDLYLVHWPIRMKKGAGFNPENVIPA--DIPATWAAMESLYDSG 499
           ++ DY+DLYL+H+P+  K         VIP+  DI  TW  ME L D+G
Sbjct: 20  IKLDYLDLYLIHFPMGFK---------VIPSNTDIRDTWEGMEDLVDAG 59

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>Q8NHP1:ARK74_HUMAN Aflatoxin B1 aldehyde reductase member 4 - Homo sapiens (Human)|
          Length = 331

 Score = 37.7 bits (86), Expect = 0.097
 Identities = 45/183 (24%), Positives = 75/183 (40%), Gaps = 11/183 (6%)
 Frame = +2

Query: 161 AAVKAGYRHIDCAQVY--GNEKEI--GFALKKVFDEGVTTRKDLFITSKLWCTNHA-PED 325
           A ++ G+  ID A +Y  G  + I  G  L+    +    R  +   +  W  N   P+ 
Sbjct: 34  AFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSD---CRVKIATKANPWIGNSLKPDS 90

Query: 326 VPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKA 505
           V   L+ +L+ LQ   VDL+ +H P                A +  T  A   L+  GK 
Sbjct: 91  VRSQLETSLKRLQCPCVDLFYLHAPDH-------------SAPVEETLRACHQLHQEGKF 137

Query: 506 RAIGVSNFSCKKVEELLAVAR----VTPAANQVECHPVWQQ--AKLRDLCASKGIHFSAY 667
             +G+SN++  +V E+  + +    + P   Q       +Q   +L       G+ F AY
Sbjct: 138 VELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPYLRHFGLRFYAY 197

Query: 668 SPL 676
           +PL
Sbjct: 198 NPL 200

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>P55804:DHGP_ASPNG NADP(+)-dependent glycerol dehydrogenase - Aspergillus niger|
          Length = 99

 Score = 37.0 bits (84), Expect = 0.16
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 8/38 (21%)
 Frame = +2

Query: 359 LQTDYVDLYLVHWPIRMKKG--------AGFNPENVIP 448
           L+ DY+DL+LVHWPI  +K          G   EN++P
Sbjct: 20  LKVDYIDLFLVHWPIAAEKAIGVSNWTIEGLEKENILP 57

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>Q32NM7:ILDR1_XENLA Immunoglobulin-like domain-containing receptor 1 precursor -|
           Xenopus laevis (African clawed frog)
          Length = 545

 Score = 36.6 bits (83), Expect = 0.22
 Identities = 31/106 (29%), Positives = 39/106 (36%), Gaps = 2/106 (1%)
 Frame = +1

Query: 208 RQRERDRIRSQEGVRRG--RNHSERSFHHLQTMVXXXXXXXXXXXXXXXXXXXXDRLRGS 381
           R R+ D   S E   R   R HS+RS  H +                       D    +
Sbjct: 367 RNRQLDDSLSNETNWRAQERQHSDRSSGHRRDPPNNRRPRRDVSPPRRYGDSYSDESANN 426

Query: 382 IPRALADPDEERRRLQPGERHPGRHTGDVGGDGEPLRLRQGPRHRR 519
            PR  ++P  +R R  P ER      GD G  G P R  +  RHRR
Sbjct: 427 DPRGRSNPHSDRAR--PTERRRSPERGDQGRRGSPDRYSRSQRHRR 470

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>O43488:ARK72_HUMAN Aflatoxin B1 aldehyde reductase member 2 - Homo sapiens (Human)|
          Length = 359

 Score = 36.2 bits (82), Expect = 0.28
 Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
 Frame = +2

Query: 317 PEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDS 496
           P+ V   L+ +L+ LQ   VDL+ +H            P++  P  +  T  A + L+  
Sbjct: 116 PDSVRSQLETSLKRLQCPQVDLFYLH-----------APDHGTP--VEETLHACQRLHQE 162

Query: 497 GKARAIGVSNFSCKKVEELLAVAR----VTPAANQVECHPVWQQ--AKLRDLCASKGIHF 658
           GK   +G+SN++  +V E+  + +    + P   Q   +   +Q   +L       G+ F
Sbjct: 163 GKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRF 222

Query: 659 SAYSPL 676
            AY+PL
Sbjct: 223 YAYNPL 228

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>O95154:ARK73_HUMAN Aflatoxin B1 aldehyde reductase member 3 - Homo sapiens (Human)|
          Length = 331

 Score = 35.8 bits (81), Expect = 0.37
 Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
 Frame = +2

Query: 317 PEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVIPADIPATWAAMESLYDS 496
           P+ +   L+ +L+ LQ   VDL+ +H            P++  P  +  T  A   L+  
Sbjct: 88  PDSLRFQLETSLKRLQCPRVDLFYLHM-----------PDHSTP--VEETLRACHQLHQE 134

Query: 497 GKARAIGVSNFSCKKVEELLAVAR----VTPAANQVECHPVWQQ--AKLRDLCASKGIHF 658
           GK   +G+SN++  +V E+  + +    + P   Q   + + +Q   +L       G+ F
Sbjct: 135 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRF 194

Query: 659 SAYSPL 676
            A++PL
Sbjct: 195 YAFNPL 200

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>P48507:GSH0_HUMAN Glutamate--cysteine ligase regulatory subunit - Homo sapiens|
           (Human)
          Length = 274

 Score = 35.4 bits (80), Expect = 0.48
 Identities = 28/109 (25%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
 Frame = +2

Query: 269 RKDLFITSKLWCT-NHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVI 445
           R+++ +++KL+   +++      A+D     L    +D  ++  P  ++ G   + E++ 
Sbjct: 86  REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASP-PIEDGVNLSLEHLQ 144

Query: 446 PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQV 592
           P      W  +E+L  S K  AIG S+    ++E+L   A+V P +NQV
Sbjct: 145 PY-----WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188

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>Q00049:NORA_ASPFL Norsolorinic acid reductase - Aspergillus flavus|
          Length = 388

 Score = 35.0 bits (79), Expect = 0.63
 Identities = 60/250 (24%), Positives = 104/250 (41%), Gaps = 37/250 (14%)
 Frame = +2

Query: 62  MALHFVLNT--GAKIPSVGLGTWQ---SEPGVVGDAVYAA--------VKAGYRHIDCAQ 202
           +  H +L++  G ++  + LGT        GV+G+   A          ++G   ID A 
Sbjct: 13  LGYHRILSSSAGVRVSPLCLGTMSFGNGWKGVMGECDQATSFNMLDTFYESGGNFIDVAN 72

Query: 203 VY---GNEKEIG--FALKKVFDEGVTTRK-----DLFITSKL---WCTNHAPEDVPVALD 343
            Y     E+ +G   A ++  DE V + K      +F   K+   +  NHA + + +++ 
Sbjct: 73  FYQGGDTERWVGEWMAQRQNRDEIVLSTKYTMGYTMFGPQKIKSNYQGNHA-KSLRLSVK 131

Query: 344 GTLQDLQTDYVDLYLVH-WPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKARAIGV 520
            +LQ LQTDY+DL  VH W                   +     ++  L  +GK   +GV
Sbjct: 132 ASLQKLQTDYIDLLYVHMWD--------------FTTSVEEVMRSLNHLVANGKVLYLGV 177

Query: 521 SNFSCKKVEELLAVARVTPAANQVECHPVWQ----------QAKLRDLCASKGIHFSAYS 670
           S+     V +  A AR    AN +    V+Q          +  +  +C S+G+  + + 
Sbjct: 178 SDTPAWLVVKCNAFAR----ANGLTPFSVYQGHWSCAFRDFERDILPMCESEGMGLAPWG 233

Query: 671 PLGSPGTFKA 700
            LG  G F++
Sbjct: 234 VLGR-GQFRS 242

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>P43547:AAD6_YEAST Putative aryl-alcohol dehydrogenase AAD6 - Saccharomyces cerevisiae|
           (Baker's yeast)
          Length = 212

 Score = 35.0 bits (79), Expect = 0.63
 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 16/99 (16%)
 Frame = +2

Query: 149 DAVYAAVKAGYRHIDCAQVYGNEKE---IG--FALKKVFDEGVTTRKDLFIT-------- 289
           DA Y   +AG   ID A  Y NE+    IG     +K+ D+ V   K  F T        
Sbjct: 60  DAFY---EAGGNFIDTANNYQNEQSEAWIGEWMVSRKLRDQIVIATK--FTTDYKKYDVG 114

Query: 290 ---SKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 397
              S  +C NH    + V++  +L+ LQTD++D+  VHW
Sbjct: 115 GGKSANYCGNHK-RSLHVSVRDSLRKLQTDWIDILYVHW 152

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>Q00258:NORA_ASPPA Norsolorinic acid reductase - Aspergillus parasiticus|
          Length = 388

 Score = 34.7 bits (78), Expect = 0.82
 Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 11/142 (7%)
 Frame = +2

Query: 308 NHAPEDVPVALDGTLQDLQTDYVDLYLVH-WPIRMKKGAGFNPENVIPADIPATWAAMES 484
           NHA + + +++  +LQ LQTDY+DL  VH W                   +     ++  
Sbjct: 121 NHA-KSLRLSVKASLQKLQTDYIDLLYVHMWD--------------FTTSVEEVMRSLNH 165

Query: 485 LYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQVECHPVWQ---QAKLRD-------L 634
           L  +GK   +GVS+     V +  A AR    AN +    V+Q    +  RD       +
Sbjct: 166 LVANGKVLYLGVSDTPAWLVVKCNAFAR----ANGLTPFSVYQGHWSSAFRDFERDILPM 221

Query: 635 CASKGIHFSAYSPLGSPGTFKA 700
           C S+G+  + +  LG  G F++
Sbjct: 222 CESEGMGLAPWGVLGR-GQFRS 242

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>O09172:GSH0_MOUSE Glutamate--cysteine ligase regulatory subunit - Mus musculus|
           (Mouse)
          Length = 274

 Score = 34.7 bits (78), Expect = 0.82
 Identities = 28/109 (25%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
 Frame = +2

Query: 269 RKDLFITSKLWCT-NHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVI 445
           R+++ +++KL+   +++      A+D     L    +D  ++  P  ++ G   + E++ 
Sbjct: 86  REEMKVSAKLFIVGSNSSSSTRSAVDMACSVLGVAQLDSVIMASP-PIEDGVNLSLEHLQ 144

Query: 446 PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQV 592
           P      W  +E+L  S K  AIG S+    ++E+L   A+V P +NQV
Sbjct: 145 PY-----WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188

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>P42884:AAD14_YEAST Putative aryl-alcohol dehydrogenase AAD14 - Saccharomyces|
           cerevisiae (Baker's yeast)
          Length = 376

 Score = 34.7 bits (78), Expect = 0.82
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 14/97 (14%)
 Frame = +2

Query: 149 DAVYAAVKAGYRHIDCAQVYGNEKE---IG--FALKKVFDEGVTTRKDLFITSKL----- 298
           DA Y   +AG   ID A  Y NE+    IG   A +K+ D+ V   K      K      
Sbjct: 60  DAFY---EAGGNCIDTANSYQNEESEIWIGEWMASRKLRDQIVIATKFTGDYKKYEVGGG 116

Query: 299 ----WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 397
               +C NH    + V++  +L+ LQTD++D+  +HW
Sbjct: 117 KSANYCGNHK-RSLHVSVRDSLRKLQTDWIDILYIHW 152

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>P48508:GSH0_RAT Glutamate--cysteine ligase regulatory subunit - Rattus norvegicus|
           (Rat)
          Length = 274

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 28/109 (25%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
 Frame = +2

Query: 269 RKDLFITSKLWCT-NHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVI 445
           R+++ +++KL+   +++      A+D     L    +D  ++  P  ++ G   + E++ 
Sbjct: 86  REEMKVSAKLFIVGSNSSSSTRNAVDMACSVLGVAQLDSVIMASP-PIEDGVNLSLEHLQ 144

Query: 446 PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQV 592
           P      W  +E+L  S K  AIG S+    ++E+L   A+V P +NQV
Sbjct: 145 PY-----WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188

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>Q2T9Y6:GSH0_BOVIN Glutamate--cysteine ligase regulatory subunit - Bos taurus (Bovine)|
          Length = 274

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 27/109 (24%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
 Frame = +2

Query: 269 RKDLFITSKLWCT-NHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPENVI 445
           R+++ +++KL+   +++      A+D     L    +D  ++  P  ++ G   + E++ 
Sbjct: 86  REEMKVSAKLFIVGSNSSSSTRNAVDMACSVLGVAQLDSVIIASP-PVEDGVNLSLEHLQ 144

Query: 446 PADIPATWAAMESLYDSGKARAIGVSNFSCKKVEELLAVARVTPAANQV 592
           P      W  +++L  S K  AIG S+    ++E+L   A+V P +NQV
Sbjct: 145 PY-----WEELQNLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188

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>Q07747:AAD4_YEAST Probable aryl-alcohol dehydrogenase AAD4 - Saccharomyces cerevisiae|
           (Baker's yeast)
          Length = 329

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 14/97 (14%)
 Frame = +2

Query: 149 DAVYAAVKAGYRHIDCAQVYGNEKE---IGFALK--KVFDEGVTTRKDLFITSKL----- 298
           DA Y   +AG   ID A  Y NE+    IG  +K  K+ D+ V   K      K      
Sbjct: 14  DAFY---EAGGNCIDTANSYQNEESEIWIGEWMKSRKLRDQIVIATKFTGDYKKYEVGGG 70

Query: 299 ----WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 397
               +C NH    + V++  +L+ LQTD++D+  VHW
Sbjct: 71  KSANYCGNHK-HSLHVSVRDSLRKLQTDWIDILYVHW 106

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>Q05514:MAAL_CLOTT Methylaspartate ammonia-lyase - Clostridium tetanomorphum|
          Length = 413

 Score = 32.7 bits (73), Expect = 3.1
 Identities = 15/37 (40%), Positives = 21/37 (56%)
 Frame = +1

Query: 943  GRRVQIRRGDLGW*NIVSTATVPCAEGGLFSYAGGGC 1053
            G  VQI+  DLG  N ++ A + C   G+ +Y GG C
Sbjct: 325  GHMVQIKTPDLGGVNNIADAIMYCKANGMGAYCGGTC 361

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>P25612:AAD3_YEAST Putative aryl-alcohol dehydrogenase AAD3 - Saccharomyces cerevisiae|
           (Baker's yeast)
          Length = 363

 Score = 32.0 bits (71), Expect = 5.3
 Identities = 13/33 (39%), Positives = 22/33 (66%)
 Frame = +2

Query: 299 WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 397
           +C NH    + V++  +L+ LQTD++D+  VHW
Sbjct: 118 YCGNHK-RSLHVSVRDSLRKLQTDWIDILYVHW 149

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>P47182:AAD10_YEAST Putative aryl-alcohol dehydrogenase AAD10 - Saccharomyces|
           cerevisiae (Baker's yeast)
          Length = 288

 Score = 31.6 bits (70), Expect = 6.9
 Identities = 13/33 (39%), Positives = 22/33 (66%)
 Frame = +2

Query: 299 WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 397
           +C NH    + V++  +L+ LQTD++D+  VHW
Sbjct: 33  FCGNHK-RSLHVSVRDSLRKLQTDWIDILYVHW 64

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>Q80T03:MUC6_MOUSE Mucin-6 precursor - Mus musculus (Mouse)|
          Length = 2850

 Score = 31.6 bits (70), Expect = 7.0
 Identities = 13/30 (43%), Positives = 13/30 (43%)
 Frame = +1

Query: 976  GW*NIVSTATVPCAEGGLFSYAGGGCQLNC 1065
            GW N V   TVPC     FSY    C   C
Sbjct: 694  GWRNSVDNCTVPCTGNRTFSYDSQACDRTC 723

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>Q00727:STCV_EMENI Putative sterigmatocystin biosynthesis dehydrogenase stcV -|
           Emericella nidulans (Aspergillus nidulans)
          Length = 387

 Score = 31.2 bits (69), Expect = 9.1
 Identities = 54/250 (21%), Positives = 97/250 (38%), Gaps = 37/250 (14%)
 Frame = +2

Query: 62  MALHFVLN--TGAKIPSVGLGT------WQSEPG-VVGDAVYAAV----KAGYRHIDCAQ 202
           +  H VL+   G ++  + LGT      W    G V  +  +A +    +AG   ID A 
Sbjct: 13  LGYHRVLSPLAGIRVSPLCLGTMHFGGQWTRAMGDVTKETAFALLDRFYEAGGNFIDTAN 72

Query: 203 VY---GNEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNH--APEDVP------------ 331
            Y   G+EK +G   + V   G   R +L + +K   +     PE +             
Sbjct: 73  FYQGEGSEKWLG---EWVASRG--NRDELVLATKYTMSYRLTGPEKIKSNFQGSHSKSLR 127

Query: 332 VALDGTLQDLQTDYVDLYLVH-WPIRMKKGAGFNPENVIPADIPATWAAMESLYDSGKAR 508
           ++++ +L  L+TDY+DL  VH W                   +     ++  L  +GK  
Sbjct: 128 LSVEASLAKLRTDYIDLLYVHMWD--------------FSTSVEEVMQSLHHLVAAGKVL 173

Query: 509 AIGVSN------FSCKKVEELLAVARVTPAANQVECHPVWQQAKLRDLCASKGIHFSAYS 670
            IG+S+        C +      + R      +  C     + ++  +C S+G+  + + 
Sbjct: 174 NIGISDAPAWVVAKCNEYARFHGLTRFCVYQGRWACSYRDFEREILPMCQSEGLALAPWG 233

Query: 671 PLGSPGTFKA 700
            LG  G +K+
Sbjct: 234 ALGR-GQYKS 242

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>Q63563:ABCC9_RAT ATP-binding cassette transporter sub-family C member 9 - Rattus|
            norvegicus (Rat)
          Length = 1545

 Score = 31.2 bits (69), Expect = 9.1
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
 Frame = +2

Query: 269  RKDLFITSKLWCTNHAP-----EDVPVALDGTLQDLQTDYVDLYLVHWPIRMKK 415
            R  + +T KL    HA      +D  V  +GTL+D+QT  V+LY  HW   M +
Sbjct: 860  RTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELY-EHWKTLMNR 912

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>P70170:ABCC9_MOUSE ATP-binding cassette transporter sub-family C member 9 - Mus musculus|
            (Mouse)
          Length = 1546

 Score = 31.2 bits (69), Expect = 9.1
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
 Frame = +2

Query: 269  RKDLFITSKLWCTNHAP-----EDVPVALDGTLQDLQTDYVDLYLVHWPIRMKK 415
            R  + +T KL    HA      +D  V  +GTL+D+QT  V+LY  HW   M +
Sbjct: 861  RTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELY-EHWKTLMNR 913

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>Q01752:AAD_PHACH Aryl-alcohol dehydrogenase [NADP+] - Phanerochaete chrysosporium|
           (White-rot fungus) (Sporotrichum pruinosum)
          Length = 385

 Score = 31.2 bits (69), Expect = 9.1
 Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 16/122 (13%)
 Frame = +2

Query: 80  LNTGAKIPSVGLGTWQSEPGV-VGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDE 256
           ++ G K    G+GT   E    + DA Y    AG   ID A VY +E    F  + +   
Sbjct: 36  MSIGDKWHPYGMGTMDKEASFKLLDAFY---NAGGNFIDTANVYQDETSEEFIGEWMEAR 92

Query: 257 G------VTTRKDLF---------ITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLV 391
           G      V T+  L          I  K     ++ + + +++  +L+ L+T Y+D++ V
Sbjct: 93  GNRDQMVVATKYSLVYKRGASFEEIPQKTQYVGNSLKSMHISVHDSLRKLRTSYIDIFYV 152

Query: 392 HW 397
           H+
Sbjct: 153 HF 154

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>Q09134:GRPA_MEDFA Abscisic acid and environmental stress-inducible protein - Medicago|
            falcata (Sickle medic)
          Length = 159

 Score = 31.2 bits (69), Expect = 9.1
 Identities = 10/17 (58%), Positives = 14/17 (82%)
 Frame = +1

Query: 1021 GGLFSYAGGGCQLNCHG 1071
            GG +++ GGGCQ +CHG
Sbjct: 124  GGGYNHGGGGCQYHCHG 140


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 168,299,731
Number of extensions: 3468462
Number of successful extensions: 11887
Number of sequences better than 10.0: 152
Number of HSP's gapped: 11588
Number of HSP's successfully gapped: 156
Length of query: 404
Length of database: 100,686,439
Length adjustment: 115
Effective length of query: 289
Effective length of database: 69,142,514
Effective search space: 19982186546
Effective search space used: 19982186546
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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full-length cDNA and EST

Clone Information

BLAST Search Result