ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf5k17 |
|---|---|
| Clone Library Name | barley_pub |
>Q3SZ20:GLYM_BOVIN Serine hydroxymethyltransferase, mitochondrial precursor - Bos taurus| (Bovine) Length = 504 Score = 492 bits (1267), Expect = e-138 Identities = 260/469 (55%), Positives = 328/469 (69%), Gaps = 4/469 (0%) Frame = +1 Query: 604 AVRAW-GNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSE 780 A + W G + L+++DP++ L+ RE+DRQ RG+ELIASENF RA L+ALGS L NKYSE Sbjct: 39 ASKGWSGQESLSDSDPEMWELLRREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSE 98 Query: 781 GHPGARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPN 960 G+PG RYYGG + +D IE LC +RAL AF LDPA WGVNVQPYS + ANLA YT LL P+ Sbjct: 99 GYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPH 158 Query: 961 DRIMGLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFH 1140 DRIMGL+ P GGH++HGY + K++S SIFFES+ YK+NPQTG IDYD+L A F Sbjct: 159 DRIMGLDLPDGGHLTHGYMS-DVKRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFK 217 Query: 1141 PKILICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTST 1320 P+++I G S+Y R D+ARMR + D+ A L+ DMAHISGLVAAK SPF + D+VT+T Sbjct: 218 PRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTT 277 Query: 1321 THKNLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIA 1500 THK LRG R G+IF+RKG + G E Y FED+INFAVFPSLQGGPHN+ IA Sbjct: 278 THKTLRGARSGLIFYRKG----VQAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIA 333 Query: 1501 ALAITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTG 1680 A+A+ LKQ TP ++ Y Q++KNAQA+A+ALL R LV+GGTDNHLVL DLR GL G Sbjct: 334 AVAVALKQACTPMFREYSLQILKNAQAMANALLERGYSLVSGGTDNHLVLVDLRPKGLDG 393 Query: 1681 KNFEKVCELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 E+V EL I+ NK GD +I+PGG+R+G PA+T+RG LEDDF + F+ Sbjct: 394 ARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRGFLEDDFRKVVGFIDEGVN 453 Query: 1861 IAGSVLKQHGKVQ--KEF-LRGLENNKDIIELGNQVEAFASQFAMPGFD 1998 I V + K+Q K F L+ E + + +L +VE FA F MPGFD Sbjct: 454 IGLEVKSKTTKLQDFKSFLLKDPETSHQLADLRQRVEQFARAFPMPGFD 502
>P14519:GLYM_RABIT Serine hydroxymethyltransferase, mitochondrial precursor -| Oryctolagus cuniculus (Rabbit) Length = 504 Score = 489 bits (1258), Expect = e-137 Identities = 260/468 (55%), Positives = 327/468 (69%), Gaps = 4/468 (0%) Frame = +1 Query: 604 AVRAW-GNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSE 780 A R W G + L++ DP++ L++RE+DRQ RG+ELIASENF RA L+ALGS L NKYSE Sbjct: 39 ASRGWTGQESLSDTDPEMWELLQREKDRQCRGLELIASENFCIRAALEALGSCLNNKYSE 98 Query: 781 GHPGARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPN 960 G+PG RYYGG + +D IE LC +RAL AF LDPA WGVNVQPYS + ANLA YT LL P+ Sbjct: 99 GYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPH 158 Query: 961 DRIMGLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFH 1140 DRIMGL+ P GGH++HGY + K+VS SIFFES+ YK+NPQTG IDY++L A F Sbjct: 159 DRIMGLDLPDGGHLTHGYMS-DVKRVSATSIFFESMPYKLNPQTGLIDYEQLALTARLFR 217 Query: 1141 PKILICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTST 1320 P+++I G S+Y R D+ARMR + D+ A L+ DMAHISGLVAAK SPF + DVVT+T Sbjct: 218 PRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTT 277 Query: 1321 THKNLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIA 1500 THK LRG R G+IF+RKG R G E Y FED+INFAVFPSLQGGPHN+ IA Sbjct: 278 THKTLRGARSGLIFYRKG----VRTVDPKTGQEIPYTFEDRINFAVFPSLQGGPHNHAIA 333 Query: 1501 ALAITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTG 1680 A+A+ LKQ TP ++ Y QV+KNA+A+A ALL R LV+GGTDNHLVL DLR GL G Sbjct: 334 AVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDG 393 Query: 1681 KNFEKVCELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 E+V EL I+ NK GD +I+PGG+R+G PA+T+R EDDF + DF+ Sbjct: 394 ARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVN 453 Query: 1861 IAGSVLKQHGKVQ--KEF-LRGLENNKDIIELGNQVEAFASQFAMPGF 1995 I V ++ K+Q K F L+ E ++ + +L +V+ FA F MPGF Sbjct: 454 IGLEVKRKTAKLQDFKSFLLKDPETSQHLADLRRRVQQFARAFPMPGF 501
>P34897:GLYM_HUMAN Serine hydroxymethyltransferase, mitochondrial precursor - Homo| sapiens (Human) Length = 504 Score = 488 bits (1257), Expect = e-137 Identities = 259/469 (55%), Positives = 328/469 (69%), Gaps = 4/469 (0%) Frame = +1 Query: 604 AVRAW-GNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSE 780 A R W G + L+++DP++ L++RE+DRQ RG+ELIASENF RA L+ALGS L NKYSE Sbjct: 39 ANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSE 98 Query: 781 GHPGARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPN 960 G+PG RYYGG + +D IE LC +RAL AF LDPA WGVNVQPYS + ANLAVYT LL P+ Sbjct: 99 GYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPH 158 Query: 961 DRIMGLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFH 1140 DRIMGL+ P GGH++HGY + K++S SIFFES+ YK+NP+TG IDY++L A F Sbjct: 159 DRIMGLDLPDGGHLTHGYMS-DVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFR 217 Query: 1141 PKILICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTST 1320 P+++I G S+Y R D+ARMR + D+ A L+ DMAHISGLVAAK SPF + D+VT+T Sbjct: 218 PRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTT 277 Query: 1321 THKNLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIA 1500 THK LRG R G+IF+RKG + G E Y FED+INFAVFPSLQGGPHN+ IA Sbjct: 278 THKTLRGARSGLIFYRKG----VKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIA 333 Query: 1501 ALAITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTG 1680 A+A+ LKQ TP ++ Y QV+KNA+A+A ALL R LV+GGTDNHLVL DLR GL G Sbjct: 334 AVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDG 393 Query: 1681 KNFEKVCELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 E+V EL I+ NK GD +I+PGG+R+G PA+T+R EDDF + DF+ Sbjct: 394 ARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVN 453 Query: 1861 IAGSVLKQHGKVQ--KEF-LRGLENNKDIIELGNQVEAFASQFAMPGFD 1998 I V + K+Q K F L+ E ++ + L +VE FA F MPGFD Sbjct: 454 IGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFD 502
>P07511:GLYC_RABIT Serine hydroxymethyltransferase, cytosolic - Oryctolagus cuniculus| (Rabbit) Length = 484 Score = 482 bits (1240), Expect = e-135 Identities = 248/462 (53%), Positives = 323/462 (69%), Gaps = 6/462 (1%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 QPL ++D +V+ ++++E +RQ G+ELIASENF RAVL+ALGS L NKYSEG+PG RYY Sbjct: 24 QPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG +HID +E LC +RAL A+GLDP CWGVNVQPYS + AN AVYT L+ P+ RIMGL+ Sbjct: 84 GGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 P GGH++HG+ T KK+S SIFFES++YKVNP TGYIDYD+LE+ A FHPK++I G Sbjct: 144 PDGGHLTHGFMTDK-KKISATSIFFESMAYKVNPDTGYIDYDRLEENARLFHPKLIIAGT 202 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S Y R D+ R+R IAD+ GA LM DMAHISGLV A SPF++C VVT+TTHK LRG Sbjct: 203 SCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSPFEHCHVVTTTTHKTLRGC 262 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 R G+IF+R+G R G E Y+ E IN AVFP LQGGPHN+ IA +A+ LKQ Sbjct: 263 RAGMIFYRRG----VRSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQ 318 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 TPE+K Y +QV+ N +AL++AL+ ++VTGG+DNHL+L DLR+ G G EKV E Sbjct: 319 AMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLE 378 Query: 1705 LCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQ 1884 C I+ NK GD ++ P G+R+GTPA+T+RG LE DF+ +A F+ R ++ + Sbjct: 379 ACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTVQIQDD 438 Query: 1885 HG-----KVQKEFLRGLENNKDIIE-LGNQVEAFASQFAMPG 1992 G K KE L G E ++ + L +VE+FA+ F +PG Sbjct: 439 TGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPG 480
>P50432:GLYC_CAEEL Serine hydroxymethyltransferase - Caenorhabditis elegans| Length = 507 Score = 480 bits (1236), Expect = e-135 Identities = 246/456 (53%), Positives = 316/456 (69%), Gaps = 4/456 (0%) Frame = +1 Query: 637 EADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQ 816 + DP+V +M+ E+ RQ RG+ELIASENF +AV+DALGS + NKYSEG+PGARYYGGN+ Sbjct: 54 KVDPEVFDIMKNEKKRQRRGLELIASENFTSKAVMDALGSAMCNKYSEGYPGARYYGGNE 113 Query: 817 HIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGG 996 ID +E LC +RAL FGLDPA WGVNVQP S + AN AVYT ++ N RIMGL+ P GG Sbjct: 114 FIDQMELLCQKRALEVFGLDPAKWGVNVQPLSGSPANFAVYTAIVGSNGRIMGLDLPDGG 173 Query: 997 HVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYP 1176 H++HG++TP+ +KVS S FF+SL YKV+P TG IDYDKLE AM F PK +I G S Y Sbjct: 174 HLTHGFFTPA-RKVSATSEFFQSLPYKVDPTTGLIDYDKLEQNAMLFRPKAIIAGVSCYA 232 Query: 1177 REWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGI 1356 R D+ R R IA K GA LM DMAHISGLVAA SPF+Y DVVT+TTHK+LRGPRG + Sbjct: 233 RHLDYERFRKIATKAGAYLMSDMAHISGLVAAGLIPSPFEYSDVVTTTTHKSLRGPRGAL 292 Query: 1357 IFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATP 1536 IF+RKG + ++G + YD E+KIN AVFP LQGGPHN+ IA +A+ L+Q + Sbjct: 293 IFYRKGVR-----STNAKGVDTLYDLEEKINSAVFPGLQGGPHNHTIAGIAVALRQCLSE 347 Query: 1537 EYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHI 1716 ++ Y +QV+KNA+ LA + + L TGGTDNHL+L DLR G+ G E V +L HI Sbjct: 348 DFVQYGEQVLKNAKTLAERMKKHGYALATGGTDNHLLLVDLRPIGVEGARAEHVLDLAHI 407 Query: 1717 SINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQHGKV 1896 + NK GD ++ PGG+R+GTPA+T+RG E DFE + DF+ QIA + GK Sbjct: 408 ACNKNTCPGDVSALRPGGIRLGTPALTSRGFQEQDFEKVGDFIHEGVQIAKKYNAEAGKT 467 Query: 1897 QKEFLRGLENN----KDIIELGNQVEAFASQFAMPG 1992 K+F E N KD+ +L +VE F+++F +PG Sbjct: 468 LKDFKSFTETNEPFKKDVADLAKRVEEFSTKFEIPG 503
>Q9SZJ5:GLYM_ARATH Serine hydroxymethyltransferase, mitochondrial precursor -| Arabidopsis thaliana (Mouse-ear cress) Length = 517 Score = 480 bits (1235), Expect = e-134 Identities = 247/465 (53%), Positives = 326/465 (70%), Gaps = 6/465 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N PL E DP++ ++E E+ RQ +G+ELI SENF +V+ A+GS +TNKYSEG+PGARY Sbjct: 52 NAPLEEVDPEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARY 111 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGGN++ID E LC +RAL AF LDP WGVNVQP S + AN VYT LL P++RIM L+ Sbjct: 112 YGGNEYIDMAETLCQKRALEAFRLDPEKWGVNVQPLSGSPANFHVYTALLKPHERIMALD 171 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 P GGH+SHGY T + KK+S SIFFE++ Y+++ TGYIDYD++E A F PK+++ G Sbjct: 172 LPHGGHLSHGYQTDT-KKISAVSIFFETMPYRLDESTGYIDYDQMEKSATLFRPKLIVAG 230 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y R +D+AR+R + +K AV++ DMAHISGLVAA SPFDY DVVT+TTHK+LRG Sbjct: 231 ASAYARLYDYARIRKVCNKQKAVMLADMAHISGLVAANVIPSPFDYADVVTTTTHKSLRG 290 Query: 1342 PRGGIIFFRKG-KNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITL 1518 PRG +IFFRKG K + K QG E YDFEDKIN AVFP LQGGPHN+ I LA+ L Sbjct: 291 PRGAMIFFRKGVKEINK------QGKEVLYDFEDKINQAVFPGLQGGPHNHTITGLAVAL 344 Query: 1519 KQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKV 1698 KQ T EYKAY +QV+ N+ A L+ R LV+GGTDNHLVL +L+ G+ G EKV Sbjct: 345 KQATTSEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKV 404 Query: 1699 CELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVL 1878 E HI+ NK + GD ++ PGG+R+GTPA+T+RG +E+DF +A++ +A IA V Sbjct: 405 LEAVHIASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVK 464 Query: 1879 KQ-HGKVQKEFLRGLENN----KDIIELGNQVEAFASQFAMPGFD 1998 + G K+F+ +E++ +I +L ++VE FA QF GF+ Sbjct: 465 SEAQGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFPTIGFE 509
>P34899:GLYM_PEA Serine hydroxymethyltransferase, mitochondrial precursor - Pisum| sativum (Garden pea) Length = 518 Score = 479 bits (1233), Expect = e-134 Identities = 248/465 (53%), Positives = 325/465 (69%), Gaps = 6/465 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N PL DP++ ++E E+ RQ +G+ELI SENF +V+ A+GS +TNKYSEG+PGARY Sbjct: 53 NSPLEVIDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 112 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGGN++ID E LC +RAL AF LDPA WGVNVQP S + +N VYT LL P+DRIM L+ Sbjct: 113 YGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPSNFQVYTALLKPHDRIMALD 172 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 P GGH+SHGY T + KK+S SIFFE++ Y+++ TGYIDYD+LE A F PK+++ G Sbjct: 173 LPHGGHLSHGYQTDT-KKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAG 231 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y R +D+AR+R + DK AVL+ DMAHISGLVAA SPFDY DVVT+TTHK+LRG Sbjct: 232 ASAYARLYDYARIRKVCDKQKAVLLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRG 291 Query: 1342 PRGGIIFFRKG-KNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITL 1518 PRG +IFFRKG K + K QG E YD+EDKIN AVFP LQGGPHN+ I LA+ L Sbjct: 292 PRGAMIFFRKGLKEVNK------QGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVAL 345 Query: 1519 KQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKV 1698 KQ TPEY+AY +QV+ N+ A AL + LV+GGT+NHLVL +L+ G+ G EKV Sbjct: 346 KQATTPEYRAYQEQVLSNSSKFAKALSEKGYDLVSGGTENHLVLVNLKNKGIDGSRVEKV 405 Query: 1699 CELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV- 1875 EL HI+ NK + GD ++ PGG+R+GTPA+T+RG +E+DF +A++ A +A V Sbjct: 406 LELVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFVKVAEYFDAAVSLALKVK 465 Query: 1876 LKQHGKVQKEFLRGLENN----KDIIELGNQVEAFASQFAMPGFD 1998 + G K+F+ L+ + +I +L + VE FA QF GF+ Sbjct: 466 AESKGTKLKDFVEALQTSSYVQSEISKLKHDVEEFAKQFPTIGFE 510
>P35623:GLYC_SHEEP Serine hydroxymethyltransferase, cytosolic - Ovis aries (Sheep)| Length = 484 Score = 478 bits (1229), Expect = e-134 Identities = 252/485 (51%), Positives = 328/485 (67%), Gaps = 6/485 (1%) Frame = +1 Query: 556 PAKRQAAGADLEARRRAVRAWGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRA 735 P + ADL + + A QPL + D +V+ ++++E +RQ G+ELIASENF RA Sbjct: 4 PVNKAPRDADLWSLHEKMLA---QPLKDNDVEVYNIIKKESNRQRVGLELIASENFASRA 60 Query: 736 VLDALGSHLTNKYSEGHPGARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSC 915 VL+ALGS L NKYSEG+PG RYYGG + ID +E LC +RAL +GLDP CWGVNVQPYS Sbjct: 61 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEVLCQKRALQVYGLDPECWGVNVQPYSG 120 Query: 916 TSANLAVYTGLLLPNDRIMGLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTG 1095 + AN AVYT L+ P+ RIMGL+ P GGH++HG+ T KK+S SIFFES+ YKVNP TG Sbjct: 121 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK-KKISATSIFFESMPYKVNPDTG 179 Query: 1096 YIDYDKLEDRAMDFHPKILICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAK 1275 YI+YD+LE+ A FHP+++I G S Y R D+AR+R IAD GA LM DMAHISGLVAA Sbjct: 180 YINYDQLEENARLFHPRLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAG 239 Query: 1276 ECRSPFDYCDVVTSTTHKNLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFA 1455 SPF++C VV++TTHK LRG R G+IF+RKG R G E Y+ E IN A Sbjct: 240 VVPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKG----VRSVDPKTGKETRYNLESLINSA 295 Query: 1456 VFPSLQGGPHNNHIAALAITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTD 1635 VFP LQGGPHN+ IA +A+ LKQ TPE++AY +QV+ N +ALA AL+ R+VTGG+D Sbjct: 296 VFPGLQGGPHNHAIAGVAVALKQAMTPEFRAYQRQVVANCRALAEALMGLGYRVVTGGSD 355 Query: 1636 NHLVLWDLRTFGLTGKNFEKVCELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLE 1815 NHL+L DLR+ G G EKV E C I+ NK GD ++ P G+R+GTPA+T+RG LE Sbjct: 356 NHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLE 415 Query: 1816 DDFEVIADFLIRATQIAGSVLKQHG--KVQKEFLRGL----ENNKDIIELGNQVEAFASQ 1977 +DF +A F+ R ++ + G KEF+ L E+ + + L +VE+FA+ Sbjct: 416 EDFRKVAHFIHRGIELTLQIQDAVGVKATLKEFMEKLAGAEEHQRAVTALRAEVESFATL 475 Query: 1978 FAMPG 1992 F +PG Sbjct: 476 FPLPG 480
>P50433:GLYM_SOLTU Serine hydroxymethyltransferase, mitochondrial precursor - Solanum| tuberosum (Potato) Length = 518 Score = 477 bits (1228), Expect = e-134 Identities = 247/465 (53%), Positives = 325/465 (69%), Gaps = 6/465 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N PL DP++ ++E E+ RQ +G+ELI SENF +V+ A+GS +TNKYSEG+PGARY Sbjct: 53 NAPLEVVDPEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARY 112 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGGN++ID E LC +RAL AF LDPA WGVNVQP S + AN VYT LL P++RIM L+ Sbjct: 113 YGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFQVYTALLKPHERIMALD 172 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 P GGH+SHGY T + KK+S SIFFE++ Y+++ TGYIDYD+LE A F PK+++ G Sbjct: 173 LPHGGHLSHGYQTDT-KKISAVSIFFETMPYRLDESTGYIDYDQLEKSATLFRPKLIVAG 231 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y R +D+ R+R + +K A+L+ DMAHISGLVAA SPFDY DVVT+TTHK+LRG Sbjct: 232 ASAYARLYDYDRIRKVCNKQKAILLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRG 291 Query: 1342 PRGGIIFFRKG-KNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITL 1518 PRG +IF+RKG K + K QG E YD+EDKIN AVFP LQGGPHN+ I LA+ L Sbjct: 292 PRGAMIFYRKGVKEVNK------QGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVAL 345 Query: 1519 KQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKV 1698 KQ TPEY+AY +QV+ N+ A AL + LV+GGTDNHLVL +++ G+ G EKV Sbjct: 346 KQATTPEYRAYQEQVLSNSSKFAQALGEKGYELVSGGTDNHLVLVNMKNKGIDGSRVEKV 405 Query: 1699 CELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV- 1875 E HI+ NK + GD ++ PGG+R+GTPA+T+RG LE+DF +ADF A +IA V Sbjct: 406 LEAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFLEEDFVKVADFFDAAVKIAVKVK 465 Query: 1876 LKQHGKVQKEFLRGLENN----KDIIELGNQVEAFASQFAMPGFD 1998 + G K+F+ LE++ +I +L + VE +A QF GF+ Sbjct: 466 AETQGTKLKDFVATLESSAPIKSEIAKLRHDVEEYAKQFPTIGFE 510
>Q60V73:GLYC_CAEBR Serine hydroxymethyltransferase - Caenorhabditis briggsae| Length = 484 Score = 476 bits (1224), Expect = e-133 Identities = 245/457 (53%), Positives = 315/457 (68%), Gaps = 4/457 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP+V +M+ E+ RQ RG+ELIASENF +AV+DALGS + NKYSEG+PGARYYGGN+ I Sbjct: 33 DPEVFNIMKNEKSRQRRGLELIASENFTSKAVMDALGSAMCNKYSEGYPGARYYGGNEFI 92 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E LC +RAL FGLDPA WGVNVQ S + AN AVYT L+ N RIMGL+ P GGH+ Sbjct: 93 DQMEILCQKRALEVFGLDPAKWGVNVQSLSGSPANFAVYTALVGANGRIMGLDLPDGGHL 152 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG++TP+ +KVS S FF+S+ YKV+ Q+G IDYDKLE+ AM F PK+LI G S Y R Sbjct: 153 THGFFTPA-RKVSATSEFFQSMPYKVDAQSGLIDYDKLEENAMLFRPKVLIAGVSCYARH 211 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 D+ R R IA K GA LM DMAHISGLVAA SPF+Y DVVT+TTHK+LRGPRG +IF Sbjct: 212 LDYERFRKIATKAGAYLMSDMAHISGLVAAGLIPSPFEYSDVVTTTTHKSLRGPRGAMIF 271 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 +RKG ++G E YD E+KIN AVFP LQGGPHN+ IA +A+ LKQ + ++ Sbjct: 272 YRKGVRSVN-----AKGVETLYDLEEKINSAVFPGLQGGPHNHTIAGIAVALKQCLSEDF 326 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 Y +Q++KNA+ LA L + L TGGTDNHL+L DLR G+ G E + +L HI+ Sbjct: 327 VQYGEQILKNAKTLAERLKKHGYSLATGGTDNHLLLVDLRPIGVEGARAEHILDLAHIAC 386 Query: 1723 NKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQHGKVQK 1902 NK GD ++ PGG+R+GTPA+T+RG E DFE + DF+ QIA + GK K Sbjct: 387 NKNTCPGDVSALRPGGIRLGTPALTSRGFKEQDFEKVGDFIHEGVQIAKKYNAEAGKTLK 446 Query: 1903 EFLRGLENN----KDIIELGNQVEAFASQFAMPGFDV 2001 +F N +++ EL +VE F+ +F +PG D+ Sbjct: 447 DFKAFTATNEQFKQEVAELAKRVEEFSGKFEIPGNDL 483
>Q5E9P9:GLYC_BOVIN Serine hydroxymethyltransferase, cytosolic - Bos taurus (Bovine)| Length = 484 Score = 474 bits (1219), Expect = e-133 Identities = 245/462 (53%), Positives = 321/462 (69%), Gaps = 6/462 (1%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 QPL + D +V+ ++++E +RQ G+ELIASENF RAVL+ALGS L NKYSEG+PG RYY Sbjct: 24 QPLKDNDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG + ID +E LC +RAL +GLD CWGVNVQPYS + AN AVYT L+ P+ RIMGL+ Sbjct: 84 GGTEFIDELEVLCQKRALQVYGLDSQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 P GGH++HG+ T KK+S SIFFES+ YKVNP TGYI+YD+LE+ A FHP+++I G Sbjct: 144 PDGGHLTHGFMTDK-KKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPRLIIAGT 202 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S Y R D+AR+R IAD GA LM DMAH+SGLVAA SPF++C VV++TTHK LRG Sbjct: 203 SCYSRNLDYARLRKIADDNGAYLMADMAHVSGLVAAGVVPSPFEHCHVVSTTTHKTLRGC 262 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 R G+IF+RKG R G E Y+ E IN AVFP LQGGPHN+ IA +A+ LKQ Sbjct: 263 RAGMIFYRKG----VRSVDPKTGRETRYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQ 318 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 TPE++AY +QV+ N +ALA AL+ R+VTGG+DNHL+L DLR+ G G EKV E Sbjct: 319 AMTPEFRAYQRQVVANCRALAEALMGLGYRVVTGGSDNHLILVDLRSKGTDGGRAEKVLE 378 Query: 1705 LCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQ 1884 C I+ NK GD ++ P G+R+GTPA+T+RG LE+DF+ +A F+ R ++ + Sbjct: 379 ACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQDA 438 Query: 1885 HG--KVQKEFLRGL----ENNKDIIELGNQVEAFASQFAMPG 1992 G KEF+ L E+++ + L +VE+FA+ F +PG Sbjct: 439 VGVKATLKEFMEKLAGAEEHHRAVAALRAEVESFATLFPLPG 480
>P49357:GLYM_FLAPR Serine hydroxymethyltransferase 1, mitochondrial precursor - Flaveria| pringlei Length = 517 Score = 473 bits (1217), Expect = e-132 Identities = 245/464 (52%), Positives = 323/464 (69%), Gaps = 5/464 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N PL DP++ ++E E+ RQ +G+ELI SENF +V+ A+GS +TNKYSEG+PGARY Sbjct: 53 NAPLEVVDPEIADIIELEKARQWKGLELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARY 112 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGGN++ID E LC +RAL AF LDPA WGVNVQP S + AN VYT LL +DRIM L+ Sbjct: 113 YGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALD 172 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 P GGH+SHGY T + KK+S SIFFE++ Y++N TGYIDYD+LE A F PK+++ G Sbjct: 173 LPHGGHLSHGYQTDT-KKISAVSIFFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAG 231 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y R +D+AR+R + DK A+++ DMAHISGLVAA SPFDY DVVT+TTHK+LRG Sbjct: 232 ASAYARLYDYARIRKVCDKQKAIMLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRG 291 Query: 1342 PRGGIIFFRKG-KNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITL 1518 PRG +IFFRKG K + K QG E YD+EDKIN AVFP LQGGPHN+ I LA+ L Sbjct: 292 PRGAMIFFRKGLKEVNK------QGKEVFYDYEDKINQAVFPGLQGGPHNHTITGLAVAL 345 Query: 1519 KQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKV 1698 KQ T EYKAY +QVM N+ A L++ LV+GGT+NHLVL +L+ G+ G EKV Sbjct: 346 KQATTAEYKAYQEQVMSNSAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSKVEKV 405 Query: 1699 CELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVL 1878 E HI+ NK + GD ++ PGG+R+GTPA+T+RG +E+DF +A F A ++A + Sbjct: 406 LEAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYFFDLAVKLAVKIK 465 Query: 1879 -KQHGKVQKEFLRGLENN---KDIIELGNQVEAFASQFAMPGFD 1998 + G K+F+ +E++ +I +L + VE +A QF GF+ Sbjct: 466 GEAKGTKLKDFVTAMESSAIQSEISKLRHDVEEYAKQFPTIGFE 509
>P50431:GLYC_MOUSE Serine hydroxymethyltransferase, cytosolic - Mus musculus (Mouse)| Length = 478 Score = 473 bits (1217), Expect = e-132 Identities = 247/463 (53%), Positives = 318/463 (68%), Gaps = 6/463 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +QPL ++D +V++++++E +RQ G+ELIASENF RAVL+ALGS L NKYSEG+PG RY Sbjct: 17 SQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGSSLNNKYSEGYPGQRY 76 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + ID +E LC +RAL A+ LDP CWGVNVQPYS + AN AVYT L+ P+ RIMGL+ Sbjct: 77 YGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLD 136 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 P GGH++HG+ T KK+S SIFFES+ YKV P+TGYI+YD+LE+ A FHPK++I G Sbjct: 137 LPDGGHLTHGFMTDK-KKISATSIFFESMPYKVYPETGYINYDQLEENASLFHPKLIIAG 195 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S Y R D+AR+R IAD GA LM DMAHISGLVAA SPF++C VVT+TTHK LRG Sbjct: 196 TSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRG 255 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 R G+IF+RKG R G E Y+ E IN AVFP LQGGPHN+ IA +A+ LK Sbjct: 256 CRAGMIFYRKG----VRSVDPKTGKETYYELESLINSAVFPGLQGGPHNHAIAGVAVALK 311 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 Q T E+K Y QV+ N +AL+ AL ++VTGG+DNHL+L DLR+ G G EKV Sbjct: 312 QAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKGTDGGRAEKVL 371 Query: 1702 ELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV-- 1875 E C I+ NK GD ++ P G+R+GTPA+T+RG LE+DF+ +A F+ R ++ + Sbjct: 372 EACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQS 431 Query: 1876 ---LKQHGKVQKEFLRGLEN-NKDIIELGNQVEAFASQFAMPG 1992 K K KE L G E + L +VE FAS F++PG Sbjct: 432 HMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPG 474
>P34896:GLYC_HUMAN Serine hydroxymethyltransferase, cytosolic - Homo sapiens (Human)| Length = 483 Score = 469 bits (1208), Expect = e-131 Identities = 245/461 (53%), Positives = 316/461 (68%), Gaps = 5/461 (1%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 QPL ++D +V+ ++++E +RQ G+ELIASENF RAVL+ALGS L NKYSEG+PG RYY Sbjct: 24 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG + ID +E LC +RAL A+ LDP CWGVNVQPYS + AN AVYT L+ P+ RIMGL+ Sbjct: 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 P GGH++HG+ T KK+S SIFFES+ YKVNP TGYI+YD+LE+ A FHPK++I G Sbjct: 144 PDGGHLTHGFMTDK-KKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT 202 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S Y R ++AR+R IAD+ GA LM DMAHISGLVAA SPF++C VVT+TTHK LRG Sbjct: 203 SCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGC 262 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 R G+IF+RKG + G E Y+ E IN AVFP LQGGPHN+ IA +A+ LKQ Sbjct: 263 RAGMIFYRKG----VKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQ 318 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 T E+K Y QV+ N +AL+ AL ++VTGG+DNHL+L DLR+ G G EKV E Sbjct: 319 AMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLE 378 Query: 1705 LCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQ 1884 C I+ NK GD ++ P G+R+GTPA+T+RG LE DF+ +A F+ R ++ + Sbjct: 379 ACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSD 438 Query: 1885 HG-----KVQKEFLRGLENNKDIIELGNQVEAFASQFAMPG 1992 G K KE L G + + L +VE+FAS F +PG Sbjct: 439 TGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPG 479
>P49358:GLYN_FLAPR Serine hydroxymethyltransferase 2, mitochondrial precursor - Flaveria| pringlei Length = 517 Score = 467 bits (1201), Expect = e-130 Identities = 243/464 (52%), Positives = 320/464 (68%), Gaps = 5/464 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N PL DP++ ++E E+ RQ +G+ELI SENF +V+ A+GS +TNKYSEG+PGARY Sbjct: 53 NAPLEVGDPEIADIIELEKARQWKGLELILSENFTSLSVMQAVGSVMTNKYSEGYPGARY 112 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGGN++ID E LC +RAL AF LD A WGVNVQP S + AN VYT LL +DRIM L+ Sbjct: 113 YGGNEYIDMAETLCQKRALEAFRLDAAKWGVNVQPLSGSPANFHVYTALLKAHDRIMALD 172 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 P GGH+SHGY T + KK+S SIFFE++ Y++N TGYIDYD+LE A F PK+++ G Sbjct: 173 LPHGGHLSHGYQTDT-KKISAVSIFFETMPYRLNESTGYIDYDQLEKSATLFRPKLIVAG 231 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y R +D+AR+R + DK A+L+ DMAHISGLVAA SPFDY DVVT+TTHK+LRG Sbjct: 232 ASAYARLYDYARIRKVCDKQKAILLADMAHISGLVAAGVIPSPFDYADVVTTTTHKSLRG 291 Query: 1342 PRGGIIFFRKG-KNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITL 1518 PRG +IFFRKG K + K QG E YD+EDKIN AVFP LQGGPHN+ I LA+ L Sbjct: 292 PRGAMIFFRKGVKEVNK------QGKEVLYDYEDKINQAVFPGLQGGPHNHTITGLAVAL 345 Query: 1519 KQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKV 1698 KQ T EYKAY +QVM N A L++ LV+GGT+NHLVL +L+ G+ G EKV Sbjct: 346 KQATTAEYKAYQEQVMSNCAKFAETLVKSGYELVSGGTENHLVLVNLKNKGIDGSRVEKV 405 Query: 1699 CELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVL 1878 E HI+ NK + GD ++ PGG+R+GTPA+T+RG +E+DF +A A ++A + Sbjct: 406 LEAVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAYLFDLAVKLAVKIK 465 Query: 1879 -KQHGKVQKEFLRGLENN---KDIIELGNQVEAFASQFAMPGFD 1998 + G K+F+ ++++ +I +L + VE +A QF GF+ Sbjct: 466 GEAQGTKLKDFVAAMQSSAFQSEISKLRHDVEEYAKQFPTIGFE 509
>Q5RFK5:GLYC_PONPY Serine hydroxymethyltransferase, cytosolic - Pongo pygmaeus| (Orangutan) Length = 483 Score = 466 bits (1200), Expect = e-130 Identities = 244/461 (52%), Positives = 315/461 (68%), Gaps = 5/461 (1%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 QPL ++D +V+ ++++E +RQ G+EL ASENF +AVL+ALGS L NKYSEG+PG RYY Sbjct: 24 QPLKDSDVEVYNIIKKESNRQRVGLELFASENFASQAVLEALGSCLNNKYSEGYPGQRYY 83 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG + ID +E LC +RAL A+ LDP CWGVNVQPYS + AN AVYT L+ P+ RIMGL+ Sbjct: 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 P GGH++HG+ T KK+S SIFFES+ YKVNP TGYI+YD+LE+ A FHPK++I G Sbjct: 144 PDGGHLTHGFMT-GKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT 202 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S Y R D+AR+R IAD+ GA LM DMAHISGLVAA SPF++C VVT+TTHK LRG Sbjct: 203 SCYSRNLDYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGC 262 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 R G+IF+RKG + G E Y+ E IN AVFP LQGGPHN+ IA +A+ LKQ Sbjct: 263 RAGMIFYRKG----VQSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQ 318 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 T E+K Y QV+ N +AL+ AL ++VTGG+DNHL+L DLR+ G G EKV E Sbjct: 319 AMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLE 378 Query: 1705 LCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQ 1884 C I+ NK GD ++ P G+R+GTPA+T+RG LE DF+ +A F+ R ++ + Sbjct: 379 ACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSD 438 Query: 1885 HG-----KVQKEFLRGLENNKDIIELGNQVEAFASQFAMPG 1992 G K KE L G + + L +VE+FAS F +PG Sbjct: 439 TGVRATLKEFKERLAGDKYQGAVQALREKVESFASLFPLPG 479
>Q6FUP6:GLYC_CANGA Serine hydroxymethyltransferase, cytosolic - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 469 Score = 452 bits (1163), Expect = e-126 Identities = 235/412 (57%), Positives = 290/412 (70%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L+E DP+V +++ E DRQ I+LIASENF +V DALG+ L NKYSEG+PGARYYGG Sbjct: 17 LSETDPEVEQIIKDEVDRQKHSIDLIASENFTTTSVFDALGTPLCNKYSEGYPGARYYGG 76 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 N+HID IERLC QRAL AF + P WGVNVQ S + ANL VY L+ P++R+MGL P Sbjct: 77 NEHIDRIERLCQQRALEAFHVTPDRWGVNVQTLSGSPANLQVYQALMKPHERLMGLYLPD 136 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH+SHGY T +K+S S +FES Y+VNP+TG IDYD LE A+ + PKIL+ G S+ Sbjct: 137 GGHLSHGYAT-ENRKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILYRPKILVAGTSA 195 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R D+ RMR IADKCGA LM DMAHISGLVAA SPF+Y D+VT+TTHK+LRGPRG Sbjct: 196 YCRLIDYKRMREIADKCGAYLMVDMAHISGLVAAGVIPSPFEYADIVTTTTHKSLRGPRG 255 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 +IFFR+G R + G E YD E+ INF+VFP QGGPHN+ IAALA LKQ A Sbjct: 256 AMIFFRRG----IRSVNQKTGKEIPYDLENPINFSVFPGHQGGPHNHTIAALATALKQAA 311 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 TPE+K Y QV+KNA+AL + RLV+ GTD+H+VL LR G+ G E VCE Sbjct: 312 TPEFKEYQTQVLKNAKALENEFQTLGYRLVSNGTDSHMVLVSLREKGVDGARVEYVCEKI 371 Query: 1711 HISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIA 1866 +I++NK I GD ++ PGGVRIG PAMTTRG E+DF I ++ +A + A Sbjct: 372 NIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVRYIDQAVKFA 423
>Q75BQ6:GLYC_ASHGO Serine hydroxymethyltransferase, cytosolic - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 469 Score = 448 bits (1153), Expect = e-125 Identities = 237/457 (51%), Positives = 309/457 (67%), Gaps = 4/457 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L+E+DP+V A+++ E DRQ I LIASEN AV DALG+ + NKYSEG+PGARYYGG Sbjct: 17 LSESDPEVDAIIKDEIDRQKHSIVLIASENLTSTAVFDALGTPMCNKYSEGYPGARYYGG 76 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 NQHID +E LC +RAL AF + P WGVNVQ S + ANL VY L+ P++R+MGL P Sbjct: 77 NQHIDRMELLCQRRALEAFHVTPDRWGVNVQSLSGSPANLQVYQALMKPHERLMGLHLPD 136 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH+SHGY T + +K+S S +FES Y+V+P+TG IDYD LE A+ + PKIL+ G S+ Sbjct: 137 GGHLSHGYQTET-RKISAVSTYFESFPYRVDPETGIIDYDTLEKNAVLYRPKILVAGTSA 195 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R D+ RMR IADK GA LM DMAHISGLVAA SPF+Y D+VT+TTHK+LRGPRG Sbjct: 196 YCRLIDYKRMREIADKVGAYLMVDMAHISGLVAAGVIPSPFEYADIVTTTTHKSLRGPRG 255 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 +IFFR+G R G+E YD E INF+VFP QGGPHN+ I+ALA LKQ Sbjct: 256 AMIFFRRG----VRSVHPKTGEEVMYDLEGPINFSVFPGHQGGPHNHTISALATALKQAT 311 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 TPE++ Y + V+KNA+ L + + RLV+ GTD+H+VL LR G+ G E VCE Sbjct: 312 TPEFREYQELVLKNAKVLETEFKKLNYRLVSDGTDSHMVLVSLREKGVDGARVEHVCEKI 371 Query: 1711 HISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV---LK 1881 +I++NK I GD ++ PGGVRIG PAMTTRG E+DF I ++ RA +IA S+ L Sbjct: 372 NIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFARIVGYINRAVEIARSIQQSLP 431 Query: 1882 QHGKVQKEFLRGLENNKD-IIELGNQVEAFASQFAMP 1989 + K+F +E D I +L ++ ++ ++ +P Sbjct: 432 KEANRLKDFKAKVEGGTDEIAQLAQEIYSWTEEYPLP 468
>P37291:GLYC_YEAST Serine hydroxymethyltransferase, cytosolic - Saccharomyces cerevisiae| (Baker's yeast) Length = 469 Score = 447 bits (1151), Expect = e-125 Identities = 233/440 (52%), Positives = 301/440 (68%), Gaps = 3/440 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + DP+V ++++ E +RQ I+LIASENF +V DALG+ L+NKYSEG+PGARYYGG Sbjct: 17 LVDTDPEVDSIIKDEIERQKHSIDLIASENFTSTSVFDALGTPLSNKYSEGYPGARYYGG 76 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 N+HID +E LC QRAL AF + P WGVNVQ S + ANL VY ++ P++R+MGL P Sbjct: 77 NEHIDRMEILCQQRALKAFHVTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLMGLYLPD 136 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH+SHGY T +K+S S +FES Y+VNP+TG IDYD LE A+ + PK+L+ G S+ Sbjct: 137 GGHLSHGYAT-ENRKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILYRPKVLVAGTSA 195 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R D+ RMR IADKCGA LM DMAHISGL+AA SPF+Y D+VT+TTHK+LRGPRG Sbjct: 196 YCRLIDYKRMREIADKCGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRG 255 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 +IFFR+G R + G E YD E+ INF+VFP QGGPHN+ IAALA LKQ A Sbjct: 256 AMIFFRRG----VRSINPKTGKEVLYDLENPINFSVFPGHQGGPHNHTIAALATALKQAA 311 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 TPE+K Y QV+KNA+AL S RLV+ GTD+H+VL LR G+ G E +CE Sbjct: 312 TPEFKEYQTQVLKNAKALESEFKNLGYRLVSNGTDSHMVLVSLREKGVDGARVEYICEKI 371 Query: 1711 HISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV---LK 1881 +I++NK I GD ++ PGGVRIG PAMTTRG E+DF I ++ +A + A V L Sbjct: 372 NIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVQYINKAVEFAQQVQQSLP 431 Query: 1882 QHGKVQKEFLRGLENNKDII 1941 + K+F ++ D++ Sbjct: 432 KDACRLKDFKAKVDEGSDVL 451
>O13972:GLYD_SCHPO Probable serine hydroxymethyltransferase, cytosolic -| Schizosaccharomyces pombe (Fission yeast) Length = 467 Score = 447 bits (1150), Expect = e-125 Identities = 239/459 (52%), Positives = 307/459 (66%), Gaps = 6/459 (1%) Frame = +1 Query: 628 PLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYG 807 PL E DP V +M E DRQ + LIASENF RAV+DALGS ++NKYSEG+PGARYYG Sbjct: 11 PLKEQDPTVAEIMRHEADRQRSSVVLIASENFTSRAVMDALGSVMSNKYSEGYPGARYYG 70 Query: 808 GNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPP 987 GN+ ID IE LC +RAL AF LDPA WGVNVQ S + AN+ VY ++ P+ R+MGL+ P Sbjct: 71 GNKFIDQIETLCQERALAAFNLDPAKWGVNVQCLSGSPANMQVYQAIMPPHGRLMGLDLP 130 Query: 988 SGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 SGGH+SHGY T + KK+S S +FES+ Y+V+P TG IDYD LE A F PKIL+ G S Sbjct: 131 SGGHLSHGYQTDT-KKISAVSTYFESMPYRVDPNTGLIDYDMLEHDAQLFRPKILVAGTS 189 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 +Y R D+ARMR IAD A L+ DMAHISGLV+A SPF+Y DVVT+TTHK+LRGPR Sbjct: 190 AYCRLIDYARMRQIADSVNAYLVVDMAHISGLVSAGVIPSPFEYADVVTTTTHKSLRGPR 249 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 G +IFFR+G +RK +G+ YD EDKINF+VFP QGGPHN+ I ALA+ LKQ Sbjct: 250 GAMIFFRRG--LRKHD---KKGNPIYYDLEDKINFSVFPGHQGGPHNHTITALAVALKQC 304 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 P YK Y QV+KNA+ +R +L GTD+H+VL D+++ G+ G E+V EL Sbjct: 305 QEPAYKEYQAQVVKNAKVCEEEFKKRGYKLAADGTDSHMVLVDVKSKGVDGARAERVLEL 364 Query: 1708 CHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 +I NK + D + SP G+R+GTPAMTTRG E DF + D++ RA A ++ K+ Sbjct: 365 INIVTNKNTVPSDKSAFSPSGIRVGTPAMTTRGFKEQDFVRVVDYIDRALTFAANLQKEL 424 Query: 1888 GK---VQKEFLRGL---ENNKDIIELGNQVEAFASQFAM 1986 K K+F L E ++++L +V +AS F + Sbjct: 425 PKDANKLKDFKAKLGEGEQYPELVQLQKEVAEWASSFPL 463
>Q10104:GLYC_SCHPO Probable serine hydroxymethyltransferase, cytosolic -| Schizosaccharomyces pombe (Fission yeast) Length = 472 Score = 444 bits (1143), Expect = e-124 Identities = 230/461 (49%), Positives = 304/461 (65%), Gaps = 7/461 (1%) Frame = +1 Query: 628 PLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYG 807 PLAE DP V+ ++E E+ RQ I LIASENF RAV+DALGS + NKYSEG+PGARYYG Sbjct: 17 PLAECDPTVYKILESEKSRQKESIALIASENFTSRAVMDALGSIMQNKYSEGYPGARYYG 76 Query: 808 GNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPP 987 GN+ ID ERLC RAL AF LD WGVNVQP+S + ANL Y ++ P+DR+MGL+ P Sbjct: 77 GNEFIDQAERLCQTRALEAFHLDGEKWGVNVQPHSGSPANLQAYQAVMKPHDRLMGLDLP 136 Query: 988 SGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 GGH+SHG+ TP K +S S +F ++ Y VN +TG IDYD LE A+ F PK+++ G S Sbjct: 137 HGGHLSHGFSTPQ-KAISAVSTYFSTMPYNVNKETGIIDYDSLEKAAIQFRPKVIVAGAS 195 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 +Y R D+ RMR I + C A L+CDMAHISGLVAA SPF+Y D+VT+TTHK+LRGPR Sbjct: 196 AYARLVDYKRMRKITEMCNAYLLCDMAHISGLVAAGVIPSPFEYADIVTTTTHKSLRGPR 255 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 G +IF+RKG + +G+ Y+ EDKINF+VFP QGGPHN+ I ALA+ L Q Sbjct: 256 GAMIFYRKGTRSHDK-----RGNPILYELEDKINFSVFPGHQGGPHNHTITALAVALGQA 310 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 TPE+ Y + V+ NA+A+A+A + R +LV+GGTD HLVL DL G+ G E++ EL Sbjct: 311 KTPEFYQYQKDVLSNAKAMANAFITRGYKLVSGGTDTHLVLVDLTDKGVDGARVERILEL 370 Query: 1708 CHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIA---DFLIRATQIAGSVL 1878 +IS NK + GD ++ P G+R+GTPA TTRG E DFE + D ++ T+ Sbjct: 371 VNISANKNTVPGDKSALIPRGLRLGTPACTTRGFDEKDFERVVELIDEVVSLTKKINEAA 430 Query: 1879 KQHGKVQ----KEFLRGLENNKDIIELGNQVEAFASQFAMP 1989 + GK + K ++ +I +L +V +A +F P Sbjct: 431 LKEGKSKFRDFKAYVGDGSKFSEIAKLKKEVITWAGKFDFP 471
>Q7S5N8:GLYM_NEUCR Putative serine hydroxymethyltransferase, mitochondrial precursor -| Neurospora crassa Length = 527 Score = 441 bits (1133), Expect = e-123 Identities = 233/462 (50%), Positives = 310/462 (67%), Gaps = 21/462 (4%) Frame = +1 Query: 667 ERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHIDAIERLCH 846 ++E+ RQ + I LI SENF +AVLDALGS + NKYSEG+PGARYYGGN+ IDA ERLC Sbjct: 67 QKEKQRQKQFINLIPSENFTSQAVLDALGSPMQNKYSEGYPGARYYGGNEFIDASERLCQ 126 Query: 847 QRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHVSHGYYTPS 1026 RAL FGLDP WGVNVQ S ANL VY+ L+ +DR+MGL+ P GGH+SHGY TP+ Sbjct: 127 DRALETFGLDPKEWGVNVQALSGAPANLYVYSALMDTHDRLMGLDLPHGGHLSHGYQTPT 186 Query: 1027 GKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPREWDFARMRL 1206 KK+S S +FE+L Y+++ +TGYIDY+KLE+ A+ + PKI++ G S+Y R D+AR+R Sbjct: 187 -KKISFISKYFETLPYRLDEKTGYIDYNKLEELAITYRPKIIVAGASAYSRLIDYARLRE 245 Query: 1207 IADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIFFRKGKNMR 1386 I DK A LM DMAHISGLVAAK PF + D+VT+T+HK+LRGPRG +IFFR+G Sbjct: 246 ICDKVNAYLMADMAHISGLVAAKVMPGPFTHADIVTTTSHKSLRGPRGAMIFFRRGVRRT 305 Query: 1387 KRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEYKAYIQQVM 1566 + +G+E Y+ E IN +VFP QGGPHN+ IAALA+ LKQ TPE++AY QV+ Sbjct: 306 NK-----KGEEELYNLETPINASVFPGHQGGPHNHTIAALAVALKQAQTPEFRAYQSQVL 360 Query: 1567 KNAQALASALLRRKCR------LVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISINK 1728 NA ALA+ L K + +V+GGTDNHLVL DL+ G+ G E+V EL ++ NK Sbjct: 361 ANATALAARLGEPKDKNGLGYTIVSGGTDNHLVLIDLKPQGIDGSRVERVLELVGVAANK 420 Query: 1729 TPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLK--------- 1881 + GD +++PGG+RIGTPAMTTRG E+DF +AD + RA IA + K Sbjct: 421 NTVPGDKSALTPGGLRIGTPAMTTRGFTEEDFARVADIIDRAVTIAVRINKAAKEDAVKK 480 Query: 1882 ------QHGKVQKEFLRGLENNKDIIELGNQVEAFASQFAMP 1989 K ++L E + +I++L ++VE++ + P Sbjct: 481 GNEKAANRVKTFMDYLGNGETDPEIVQLRSEVESWVGTYPCP 522
>P34898:GLYC_NEUCR Serine hydroxymethyltransferase, cytosolic - Neurospora crassa| Length = 480 Score = 440 bits (1131), Expect = e-122 Identities = 237/458 (51%), Positives = 305/458 (66%), Gaps = 5/458 (1%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L E+DP V +M++E RQ I LIASEN RAV DALGS ++NKYSEG PGARYYGG Sbjct: 18 LVESDPQVAEIMKKEVQRQRESIILIASENVTSRAVFDALGSPMSNKYSEGLPGARYYGG 77 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 NQHID IE LC RAL AF LDP WGVNVQ S + ANL VY ++ + R+MGL+ P Sbjct: 78 NQHIDEIEVLCQNRALEAFHLDPKQWGVNVQCLSGSPANLQVYQAIMPVHGRLMGLDLPH 137 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH+SHGY TP +K+S S +FE++ Y+VN TG IDYD LE A F PK+L+ G S+ Sbjct: 138 GGHLSHGYQTPQ-RKISAVSTYFETMPYRVNIDTGLIDYDTLEKNAQLFRPKVLVAGTSA 196 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R D+ RMR IAD GA L+ DMAHISGL+A++ SPF Y DVVT+TTHK+LRGPRG Sbjct: 197 YCRLIDYERMRKIADSVGAYLVVDMAHISGLIASEVIPSPFLYADVVTTTTHKSLRGPRG 256 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 +IFFR+G R G E YD EDKINF+VFP QGGPHN+ I ALA+ LKQ A Sbjct: 257 AMIFFRRG----VRSVDAKTGKETLYDLEDKINFSVFPGHQGGPHNHTITALAVALKQAA 312 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 +PE+K Y Q+V+ NA+AL L +LV+ GTD+H+VL DLR G+ G E + E Sbjct: 313 SPEFKEYQQKVVANAKALEKKLKELGYKLVSDGTDSHMVLVDLRPIGVDGARVEFLLEQI 372 Query: 1711 HISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV---LK 1881 +I+ NK + GD +++PGG+RIGTPAMT+RG E DFE +A F+ A ++ + L Sbjct: 373 NITCNKNAVPGDKSALTPGGLRIGTPAMTSRGFGEADFEKVAVFVDEAVKLCKEIQASLP 432 Query: 1882 QHGKVQKEFLRGLENN--KDIIELGNQVEAFASQFAMP 1989 + QK+F + + I EL ++ A+++ F +P Sbjct: 433 KEANKQKDFKAKIATSDIPRINELKQEIAAWSNTFPLP 470
>Q6CLQ5:GLYM_KLULA Serine hydroxymethyltransferase, mitochondrial precursor -| Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 498 Score = 433 bits (1114), Expect = e-120 Identities = 227/486 (46%), Positives = 313/486 (64%), Gaps = 8/486 (1%) Frame = +1 Query: 559 AKRQAAG-ADLEARRRAVRAWGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRA 735 AKR A A+ A A + ++ + + DP+++ ++ +ER RQ I LI SENF ++ Sbjct: 16 AKRSLASQANTGANASANQVMVSKHVQDIDPEMYDILTKERKRQKHSITLIPSENFTSKS 75 Query: 736 VLDALGSHLTNKYSEGHPGARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSC 915 V+D LGS + NKYSEG+PG RYYGGNQ ID E LC +RAL + LDP WGVNVQP S Sbjct: 76 VMDLLGSEMQNKYSEGYPGERYYGGNQFIDMAESLCQKRALELYNLDPQLWGVNVQPLSG 135 Query: 916 TSANLAVYTGLLLPNDRIMGLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTG 1095 ANL Y+ ++ NDR+MGL+ P GGH+SHGY PSG K+S S +F+++ Y V+ QTG Sbjct: 136 APANLYAYSAVMETNDRLMGLDLPHGGHLSHGYQLPSGTKISYISKYFQTMPYHVDSQTG 195 Query: 1096 YIDYDKLEDRAMDFHPKILICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAK 1275 IDYD L + F PK+++ G S+Y R D+ R + IAD CGA LM DMAHISGLVAA Sbjct: 196 IIDYDFLSKTSKLFRPKVIVAGASAYSRVLDYKRFKEIADACGAYLMSDMAHISGLVAAG 255 Query: 1276 ECRSPFDYCDVVTSTTHKNLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFA 1455 RSPF+Y D+VT+TTHK+LRGPRG +IF+RKG +RK +G E YD + +INF+ Sbjct: 256 VTRSPFEYSDIVTTTTHKSLRGPRGAMIFYRKG--VRK---VTKKGKEVLYDLDKRINFS 310 Query: 1456 VFPSLQGGPHNNHIAALAITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTD 1635 VFP QGGPHN+ I+ALA+ LKQ ATPE+K Y V++NA+ L+++ LV+GGTD Sbjct: 311 VFPGHQGGPHNHTISALAVALKQAATPEFKEYQAAVVENARIFGEELVKKGFELVSGGTD 370 Query: 1636 NHLVLWDLRTFGLTGKNFEKVCELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLE 1815 HL+L +L G+ G E + E +I+ NK I GD ++ P G+R+GTPAMTTRG Sbjct: 371 THLILINLSNLGIDGARLETLLENINIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFGP 430 Query: 1816 DDFEVIADFLIRATQIAGSVLKQHGKVQKEFLRGLENNKDIIELGNQVEAFA-------S 1974 +F +A ++ RA ++A + Q K+ L + K++ + +QV+ A Sbjct: 431 QEFAQVAAYIDRAVKLAIGIKSQESPDAKDARSKLASFKELCKESDQVKQLADEVYQWVG 490 Query: 1975 QFAMPG 1992 +F +PG Sbjct: 491 EFPVPG 496
>Q6FQ44:GLYM_CANGA Serine hydroxymethyltransferase, mitochondrial precursor - Candida| glabrata (Yeast) (Torulopsis glabrata) Length = 485 Score = 433 bits (1114), Expect = e-120 Identities = 219/460 (47%), Positives = 300/460 (65%), Gaps = 8/460 (1%) Frame = +1 Query: 637 EADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQ 816 E DP++ ++ ER RQ + LI SENF +AV+D LGS + NKYSEG+PG RYYGGNQ Sbjct: 29 EVDPEMFRILSDERSRQKHSVTLIPSENFTSKAVMDLLGSEMQNKYSEGYPGERYYGGNQ 88 Query: 817 HIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGG 996 ID E LC RAL +GLDP WGVNVQ S ANL Y+ ++ DR+MGL+ P GG Sbjct: 89 FIDKAESLCQARALDLYGLDPEKWGVNVQALSGAPANLYAYSAVMEVGDRLMGLDLPHGG 148 Query: 997 HVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYP 1176 H+SHGY PSG K+S S +F ++ Y VN +TG IDYD L + F PK+++ G S+Y Sbjct: 149 HLSHGYQLPSGTKISYISKYFNTMPYHVNTETGIIDYDTLAMTSKLFRPKVIVAGTSAYS 208 Query: 1177 REWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGI 1356 R+ D+AR R IAD CGA L+ DMAHISGLVAA SPF++ D+VT+TTHK+LRGPRG + Sbjct: 209 RKLDYARFRKIADGCGAYLLSDMAHISGLVAANVIDSPFEHSDIVTTTTHKSLRGPRGAM 268 Query: 1357 IFFRKG-KNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVAT 1533 IF+RKG K + K+ G E + F+ INF+VFP QGGPHN+ I+ALA+ LKQ T Sbjct: 269 IFYRKGIKKVNKK-----TGKETPFTFDKTINFSVFPGHQGGPHNHTISALAVALKQAKT 323 Query: 1534 PEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCH 1713 PE+ Y +QV+ NA+A LL+R LV+GGTDNHL+L +L G+ G E + E + Sbjct: 324 PEFVEYQKQVVSNAKAFGDELLKRGFELVSGGTDNHLLLLNLSNMGIDGARLEAILEKIN 383 Query: 1714 ISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQHGK 1893 I+ NK I GD ++ P G+R+GTPAMTTRG E DF+ +A+++ A +++ ++ Q Sbjct: 384 IAANKNTIPGDKSALFPSGLRVGTPAMTTRGFQEQDFKKVAEYIDNAVKLSIALKSQESA 443 Query: 1894 VQKE-------FLRGLENNKDIIELGNQVEAFASQFAMPG 1992 K+ F + + ++ + +L +V ++ F +PG Sbjct: 444 DAKDVRSKLNSFKQLCDQSEPVQKLAEEVSSWVGTFPVPG 483
>O13426:GLYC_CANAL Serine hydroxymethyltransferase, cytosolic - Candida albicans (Yeast)| Length = 470 Score = 433 bits (1114), Expect = e-120 Identities = 228/456 (50%), Positives = 307/456 (67%), Gaps = 4/456 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + DP+V +++ E DRQ I LIASENF AV DALG+ + NKYSEG+PGARYYGG Sbjct: 18 LKDTDPEVDQIIKDEIDRQQHSIVLIASENFTTTAVFDALGTPMCNKYSEGYPGARYYGG 77 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 N+HI +E LC +RAL AFGL P WGVNVQ S + ANL VY ++ P++R+MGL+ P Sbjct: 78 NEHIHRMELLCQERALKAFGLTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLMGLDLPH 137 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH+SHGY T S +K+S S +FE++ Y+V+ +TG IDYD LE A+ + PK+L+ G S+ Sbjct: 138 GGHLSHGYQTDS-RKISAVSTYFETMPYRVDLETGLIDYDMLEKTAVLYRPKVLVAGTSA 196 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R D+ RMR IADK GA L+ DMAHISGL+AA SPF+Y D+VT+TTHK+LRGPRG Sbjct: 197 YCRLIDYKRMREIADKVGAYLVVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRG 256 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 +IFFR+G R + G E YD E+ INF+VFP QGGPHN+ IAALA LKQ Sbjct: 257 AMIFFRRG----VRSVNPKTGQEILYDLENPINFSVFPGHQGGPHNHTIAALATALKQAN 312 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 TPE+K Y +QV+KNA+AL S ++ +LV+ GTD+H+VL L+ + G E VCE Sbjct: 313 TPEFKEYQEQVLKNAKALESEFTKKGYKLVSDGTDSHMVLVSLKDKQIDGARVETVCEKI 372 Query: 1711 HISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIA---DFLIRATQIAGSVLK 1881 +I++NK I GD ++ PGGVRIG PAMTTRG E+DF+ I DF + + S L Sbjct: 373 NIALNKNSIPGDKSALVPGGVRIGAPAMTTRGLGEEDFKKIVSYIDFAVNYAKEVQSQLP 432 Query: 1882 QHGKVQKEFLRGLENNKDIIE-LGNQVEAFASQFAM 1986 + K+F + + + ++ + +++ +A F + Sbjct: 433 KDANKLKDFKNAVSGDSEKLKAVRDEIYQWAGSFPL 468
>O13425:GLYM_CANAL Serine hydroxymethyltransferase, mitochondrial precursor - Candida| albicans (Yeast) Length = 493 Score = 429 bits (1103), Expect = e-119 Identities = 230/490 (46%), Positives = 320/490 (65%), Gaps = 10/490 (2%) Frame = +1 Query: 553 RPAKRQAAGADLEARRR-----AVRAWGNQPLAEADPDVHALMERERDRQVRGIELIASE 717 R + Q+ ARR + +A ++ + + DP++ ++ +ER RQ I LI SE Sbjct: 8 RSVRAQSKNLPAFARRTYAVSPSAQALISKSVQDVDPEMADILNQERTRQKNSITLIPSE 67 Query: 718 NFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVN 897 NF +AV+D LGS + NKYSEG+PG RYYGGN+ ID E LC +RAL AFGLDP+ WGVN Sbjct: 68 NFTSKAVMDLLGSEMQNKYSEGYPGERYYGGNEIIDKAEALCQKRALEAFGLDPSQWGVN 127 Query: 898 VQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYK 1077 VQP S ANL Y+ +L DRIMGL+ P GGH+SHGY T + K+S S +F+++ Y+ Sbjct: 128 VQPLSGAPANLYAYSAILEVGDRIMGLDLPHGGHLSHGYQTKT-TKISYISKYFQTMPYR 186 Query: 1078 VNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPREWDFARMRLIADKCGAVLMCDMAHIS 1257 +N +TG IDYD LE A F PK+++ G S+Y R D+ RMR ++ + GA L+ DMAHIS Sbjct: 187 LNEETGIIDYDTLEKNAQLFRPKVIVAGASAYSRVIDYKRMRQLSIRLGAYLLSDMAHIS 246 Query: 1258 GLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFE 1437 GLV+A SPF Y D+VT+TTHK+LRGPRG +IFFRKG +RK ++G E Y+ E Sbjct: 247 GLVSAVVTDSPFPYSDIVTTTTHKSLRGPRGAMIFFRKG--IRK---VTTKGKEIPYELE 301 Query: 1438 DKINFAVFPSLQGGPHNNHIAALAITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRL 1617 KINF VFP QGGPHN+ I+ALA+ LKQ PEY Y Q+V+ NA+ A AL+ + +L Sbjct: 302 RKINFLVFPGHQGGPHNHTISALAVALKQCTEPEYVKYQQEVVSNAKHFADALVSKGFKL 361 Query: 1618 VTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISINKTPIYGDNGSISPGGVRIGTPAMT 1797 V+ GTD HL+L DLR+ + G E V E +I+ NK + GD ++ P G+R+GTPAMT Sbjct: 362 VSDGTDTHLILVDLRSRNIDGARVEAVLERANIAANKNTVPGDVSALFPSGLRVGTPAMT 421 Query: 1798 TRGCLEDDFEVIADFLIRATQIAGSV-LKQHGKVQKEFLRGLENNKD----IIELGNQVE 1962 TRG ++F+ +A+F+ +A IA + ++ GKV KE L + D + +L +V Sbjct: 422 TRGFGPEEFDKVAEFIDQAVNIAIELKAQEQGKVPKELLASFKKLADESDKVKQLDKEVV 481 Query: 1963 AFASQFAMPG 1992 ++ S++ +PG Sbjct: 482 SWVSKYPVPG 491
>Q758F0:GLYM_ASHGO Serine hydroxymethyltransferase, mitochondrial precursor - Ashbya| gossypii (Yeast) (Eremothecium gossypii) Length = 497 Score = 426 bits (1095), Expect = e-118 Identities = 218/464 (46%), Positives = 305/464 (65%), Gaps = 7/464 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +Q + E DP+++ ++ +ER RQ R I LI SENF AV++ LGS + NKYSEG+PG RY Sbjct: 37 SQHVQEFDPEMYDILTKERSRQKRSITLIPSENFTSVAVMNLLGSEMQNKYSEGYPGQRY 96 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGGNQ+ID E LC +RAL +GLDPA WGVNVQ S ANL Y+ ++ DR+MGL+ Sbjct: 97 YGGNQYIDMAESLCQKRALELYGLDPAKWGVNVQSLSGAPANLYAYSAIMEVGDRMMGLD 156 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 P GGH+SHGY +G K+S S +F++++Y+V+P TG +DYD L + + F PK+++ G Sbjct: 157 LPHGGHLSHGYQLQNGNKISYISKYFQTMAYRVDPATGLVDYDTLSETSKLFRPKVIVAG 216 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y R D+ R R IAD CGA L+ DMAH+SGLVAA SPF+Y D+VT+TTHK+LRG Sbjct: 217 TSAYARVLDYKRFREIADACGAYLLSDMAHVSGLVAAGVHPSPFEYSDIVTTTTHKSLRG 276 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRG +IF+RKG +RK +G E YD + +INF+VFP+ QGGPHN+ I+ALA+ LK Sbjct: 277 PRGAMIFYRKG--IRK---VTKKGTEIMYDLDKRINFSVFPAHQGGPHNHTISALAVALK 331 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 Q ATPE+K Y V++NA+ L +R LV+GGTD HL+L DL G+ G E + Sbjct: 332 QAATPEFKNYQTAVVENAKVFGEELSKRGFSLVSGGTDTHLLLIDLSPMGIDGSRLETIL 391 Query: 1702 ELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLK 1881 E +I+ NK I GD ++ P G+R+GTPAMTTRG +F +A ++ A ++A + Sbjct: 392 ERLNIAANKNTIPGDKSALYPSGLRVGTPAMTTRGFGPAEFGRVAAYINEAVKLAIGLKS 451 Query: 1882 QHGKVQKE-------FLRGLENNKDIIELGNQVEAFASQFAMPG 1992 Q K+ F ++ + +L N+V + +Q+ +PG Sbjct: 452 QEPVDAKDAKTRLAHFKSFCAESEQVTKLANEVADWVAQYPVPG 495
>P37292:GLYM_YEAST Serine hydroxymethyltransferase, mitochondrial precursor -| Saccharomyces cerevisiae (Baker's yeast) Length = 490 Score = 421 bits (1081), Expect = e-117 Identities = 216/465 (46%), Positives = 304/465 (65%), Gaps = 8/465 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 ++P++E DP++ ++++ER RQ I LI SENF +AV+D LGS L NKYSEG+PG RY Sbjct: 30 SKPVSEGDPEMFDILQQERHRQKHSITLIPSENFTSKAVMDLLGSELQNKYSEGYPGERY 89 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGGN+ ID E LC RAL +GLDPA WGVNVQP S ANL VY+ ++ +R+MGL+ Sbjct: 90 YGGNEIIDKSESLCQARALELYGLDPAKWGVNVQPLSGAPANLYVYSAIMNVGERLMGLD 149 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 P GGH+SHGY SG +S S +F+S+ Y V+ TG IDYD L+ A F PK+++ G Sbjct: 150 LPDGGHLSHGYQLKSGTPISFISKYFQSMPYHVDHTTGLIDYDNLQVLAKAFRPKVIVAG 209 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y R D+AR + I+ CGA LM DMAHISGLVAA SPF++ D+VT+TTHK+LRG Sbjct: 210 TSAYSRLIDYARFKEISQGCGAYLMSDMAHISGLVAANVVPSPFEHSDIVTTTTHKSLRG 269 Query: 1342 PRGGIIFFRKG-KNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITL 1518 PRG +IFFRKG K++ K+ G E Y+ E KINF+VFP QGGPHN+ I A+A+ L Sbjct: 270 PRGAMIFFRKGIKSVTKK------GKEIPYELEKKINFSVFPGHQGGPHNHTIGAMAVAL 323 Query: 1519 KQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKV 1698 KQ +PE+K Y Q+++ N++ A L + +LV+GGTDNHL++ DL + G E + Sbjct: 324 KQAMSPEFKEYQQKIVDNSKWFAQELTKMGYKLVSGGTDNHLIVIDLSGTQVDGARVETI 383 Query: 1699 CELCHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV- 1875 +I+ NK I GD ++ P G+RIGTPAMTTRG ++F +A ++ A ++A ++ Sbjct: 384 LSALNIAANKNTIPGDKSALFPSGLRIGTPAMTTRGFGREEFSQVAKYIDSAVKLAENLK 443 Query: 1876 -LKQHGKVQ-----KEFLRGLENNKDIIELGNQVEAFASQFAMPG 1992 L+ K+ EF + + ++ L ++ + Q+ +PG Sbjct: 444 TLEPTTKLDARSRLNEFKKLCNESSEVAALSGEISKWVGQYPVPG 488
>O62585:GLYC_ENCCU Serine hydroxymethyltransferase, cytosolic - Encephalitozoon cuniculi| Length = 460 Score = 377 bits (969), Expect = e-104 Identities = 194/406 (47%), Positives = 269/406 (66%) Frame = +1 Query: 628 PLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYG 807 PL ADP++HAL+ E +RQ + I LIASEN+ ++ ++A GS LTNKYSEG G RYYG Sbjct: 13 PLEMADPELHALICGEVERQKKTINLIASENYAHQSAMEACGSVLTNKYSEGRVGERYYG 72 Query: 808 GNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPP 987 G +D IE LC +RAL FGLDP WGVNVQPYS + AN A+YT ++ P RIMGL+ P Sbjct: 73 GTHWVDRIELLCQKRALELFGLDPDVWGVNVQPYSGSPANFAIYTAVVPPGGRIMGLDLP 132 Query: 988 SGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 SGGH++HGY T + +K+S +S++F+S Y V G IDY+ LE DF P ILICG S Sbjct: 133 SGGHLTHGYKTKT-RKISASSVYFDSRPYTVG-SNGLIDYEGLEKTFTDFLPHILICGYS 190 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 +Y R+ D+ R++ IA + GA L D++HIS LVA+ SPF++CD+V +TT K LRGPR Sbjct: 191 AYSRDIDYKRLQSIAGRNGAFLFADISHISPLVASGLMNSPFEHCDIVMTTTQKGLRGPR 250 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 G +IF+R+ + K G D + +INFAVFP LQGGPHN+ IA +A L Sbjct: 251 GALIFYRRA--VTKNG--------ETVDLDARINFAVFPMLQGGPHNHTIAGIASALLHA 300 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 TPE+ Y ++V++N++ L S L ++TGGTDNH++L DLR+ G+ G E +C+ Sbjct: 301 GTPEFAEYTRRVVENSRELCSRLQSLGLDILTGGTDNHMLLVDLRSTGVDGAAVEHMCDA 360 Query: 1708 CHISINKTPIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 IS+N+ I G++ +SP G+R+GT A+T RG ++ + D + Sbjct: 361 LGISLNRNAIVGNSSPLSPSGIRVGTYAVTARGFGPEEMREVGDII 406
>Q67N41:GLYA_SYMTH Serine hydroxymethyltransferase - Symbiobacterium thermophilum| Length = 412 Score = 338 bits (867), Expect = 6e-92 Identities = 189/409 (46%), Positives = 259/409 (63%), Gaps = 1/409 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L DP+V A +++E +RQ R IELIASENFV +AVL+A G+ LTNKY+EG+PG RYYGG Sbjct: 4 LKRYDPEVFAAIQQEVERQQRNIELIASENFVPKAVLEAAGTVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E + +R AFG + VNVQP+S +AN AVY L P D ++G+ Sbjct: 64 CEYVDIVENIARERLKAAFGAEH----VNVQPHSGANANTAVYFAFLQPGDTVLGMNLAQ 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S SG + F + Y ++P+T I+ D++ + A PK+++ G S+ Sbjct: 120 GGHLTHG----SPVNFSGRTYNF--VPYGLDPETERINMDQVAELARQHRPKLIVAGYSA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF R R IA++ GA+LM DMAH +GL A +P ++ VVT+TTHK LRGPRG Sbjct: 174 YPRVLDFKRFREIAEEVGAILMVDMAHFAGLAATGYYPNPVEHAHVVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G I +K +F +I+ AVFP +QGGP + IAA A+ KQ++ Sbjct: 234 GAILCKK-------------------EFAKEIDKAVFPGMQGGPLMHIIAAKAVAFKQLS 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P+Y+AY QV+KNA+ALA ALL R RLVTGGTDNHL+L DLR G+TG++ E + + Sbjct: 275 DPDYRAYCGQVVKNAKALAQALLERGYRLVTGGTDNHLMLVDLRPKGITGRDAEHLLDRV 334 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 I++NK I D + G+RIGTPAMTTRG E + IAD + RA Sbjct: 335 SITVNKNAIPNDPEKPMVTSGIRIGTPAMTTRGMKEAEMVQIADLIDRA 383
>Q3A934:GLYA_CARHZ Serine hydroxymethyltransferase - Carboxydothermus hydrogenoformans| (strain Z-2901 / DSM 6008) Length = 421 Score = 338 bits (866), Expect = 7e-92 Identities = 185/409 (45%), Positives = 252/409 (61%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L + DP++ ME+E RQ IELIASENFV RAV++A+GSHLTNKY+EG PG RY Sbjct: 5 NLRLKDVDPEIFEAMEKELSRQREKIELIASENFVSRAVMEAMGSHLTNKYAEGLPGKRY 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +++D +E L +RA FG + VNVQP+S AN+A Y L P D ++G+ Sbjct: 65 YGGCEYVDVVENLARERAKKLFGAEH----VNVQPHSGAQANMAAYMAFLEPGDTVLGMN 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG V+ + + +SY V P T I+Y+K+ + A PK+++ G Sbjct: 121 LAHGGHLTHG------SPVNFSGKLYNFVSYGVEPDTEKINYEKVFELAYKHKPKMIVAG 174 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR DF ++ IAD+ GA LM DMAHI+GLVAA SP Y DVVT+TTHK LRG Sbjct: 175 ASAYPRVIDFKHLKEIADEVGAYLMVDMAHIAGLVAAGLHPSPIPYADVVTTTTHKTLRG 234 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+IF + + KI+ VFP +QGGP + IAA A+ K Sbjct: 235 PRGGVIFCKA-------------------EHAAKIDKTVFPGVQGGPLMHVIAAKAVAFK 275 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + +PE++ Y QQV+ NA+ALA L ++ RLV+GGTDNHL+L D+R GLTGK E++ Sbjct: 276 EALSPEFREYQQQVVNNAKALAEELKKQGLRLVSGGTDNHLMLVDVRPVGLTGKRAEQLL 335 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 + +++NK I Y G+RIGTPA+TTRG E + IA+ + Sbjct: 336 DEIGVTVNKNAIPYDPESPNVTSGIRIGTPAVTTRGMKEGEMAEIAEII 384
>Q7U9J7:GLYA_SYNPX Serine hydroxymethyltransferase - Synechococcus sp. (strain WH8102)| Length = 429 Score = 336 bits (861), Expect = 3e-91 Identities = 200/436 (45%), Positives = 261/436 (59%), Gaps = 2/436 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N+ LA ADP + AL+E+E+ RQ +ELIASENF RAV+DA GS LTNKY+EG P RY Sbjct: 10 NKGLAAADPAIAALIEKEQQRQETHLELIASENFASRAVMDAQGSVLTNKYAEGLPSKRY 69 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +H+DAIE L +RA FG A W NVQP+S AN AV+ LL P D IMGL+ Sbjct: 70 YGGCEHVDAIEELAIERAKELFG---AAWA-NVQPHSGAQANFAVFLALLQPGDTIMGLD 125 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG S VSG +F + Y V+ +T +D + + A++ PK+++CG Sbjct: 126 LSHGGHLTHG----SPVNVSGK--WFNVVQYGVDRETQRLDMEAIRQLALEHKPKLIVCG 179 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR DFA R IAD+ GA L+ DMAHI+GLVAA SP +CDVVT+TTHK LRG Sbjct: 180 FSAYPRTIDFAAFRAIADEVGAFLLADMAHIAGLVAAGVHPSPVPHCDVVTTTTHKTLRG 239 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I R D DF K + AVFP QGGP + IAA A+ Sbjct: 240 PRGGLILCR------------------DADFAKKFDKAVFPGSQGGPLEHVIAAKAVAFG 281 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + P +K Y Q V+ NA ALA L+ R +V+GGTDNH+VL DLR+ G+TGK + + Sbjct: 282 EALQPAFKTYSQHVVANAAALAERLIARGIDVVSGGTDNHVVLLDLRSVGMTGKVADLLV 341 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVL 1878 HI+ NK + + G+R+GT A+TTRG F +AD IA +L Sbjct: 342 SDVHITANKNTVPFDPESPFVTSGLRLGTAALTTRGFDAGAFREVADV------IADRLL 395 Query: 1879 K-QHGKVQKEFLRGLE 1923 + VQ++ LR +E Sbjct: 396 NPEDDAVQQQCLRRVE 411
>Q3AN03:GLYA_SYNSC Serine hydroxymethyltransferase - Synechococcus sp. (strain CC9605)| Length = 431 Score = 335 bits (859), Expect = 5e-91 Identities = 194/420 (46%), Positives = 253/420 (60%), Gaps = 1/420 (0%) Frame = +1 Query: 589 EARRRAVRAWGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTN 768 +A RA+ A LA++DPD+ A + +ER RQ +ELIASENF RAV+ A GS LTN Sbjct: 3 QASGRAIDA----DLAQSDPDIAAFINQERQRQETHLELIASENFASRAVMQAQGSVLTN 58 Query: 769 KYSEGHPGARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGL 948 KY+EG P RYYGG +H+DAIE L +RA FG A W NVQP+S AN AV+ L Sbjct: 59 KYAEGLPSKRYYGGCEHVDAIEELAIERAKQLFG---AAWA-NVQPHSGAQANFAVFLAL 114 Query: 949 LLPNDRIMGLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRA 1128 L P D IMGL+ GGH++HG S VSG +F + Y V+ +T +D + + A Sbjct: 115 LQPGDTIMGLDLSHGGHLTHG----SPVNVSGK--WFNVVQYGVDKETQRLDMEAIRQLA 168 Query: 1129 MDFHPKILICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDV 1308 ++ PK+++CG S+YPR DFA R IAD+ GA L+ DMAHI+GLVAA SP +CDV Sbjct: 169 LEHKPKLIVCGYSAYPRTIDFAAFRAIADEVGAYLLADMAHIAGLVAAGVHPSPVPHCDV 228 Query: 1309 VTSTTHKNLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHN 1488 VT+TTHK LRGPRGG+I R D +F K + AVFP QGGP Sbjct: 229 VTTTTHKTLRGPRGGLILCR------------------DAEFAKKFDKAVFPGSQGGPLE 270 Query: 1489 NHIAALAITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTF 1668 + IAA A+ + P +KAY QQV+ NA ALA L+ R +V+GGTDNH+VL DLR+ Sbjct: 271 HVIAAKAVAFGEALQPSFKAYSQQVVANAAALAEQLIARGIDVVSGGTDNHVVLLDLRSI 330 Query: 1669 GLTGKNFEKVCELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 G+TGK + + HI+ NK + + G+R GT A+TTRG F +AD + Sbjct: 331 GMTGKVADLLVSDVHITANKNTVPFDPESPFVTSGLRFGTAALTTRGFDSQAFREVADVI 390
>Q3AW18:GLYA_SYNS9 Serine hydroxymethyltransferase - Synechococcus sp. (strain CC9902)| Length = 429 Score = 333 bits (854), Expect = 2e-90 Identities = 190/409 (46%), Positives = 248/409 (60%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N LA ADP++ L+++ER RQ +ELIASENF +AV+ A GS LTNKY+EG P RY Sbjct: 10 NAGLASADPEISRLIDQERHRQETHLELIASENFASQAVMQAQGSVLTNKYAEGLPAKRY 69 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +H+DAIE L +RA F A W NVQP+S AN AV+ LL P D IMGL+ Sbjct: 70 YGGCEHVDAIETLAIERAKQLFD---AAWA-NVQPHSGAQANFAVFLALLKPGDTIMGLD 125 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG S VSG +F + Y V+P T +D + + A++ PK+++CG Sbjct: 126 LSHGGHLTHG----SPVNVSGK--WFNVVQYGVDPTTQRLDMEAIRKLALEHKPKLIVCG 179 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR DFA R IAD+ GA L+ DMAHI+GLVAA SP +CDVVT+TTHK LRG Sbjct: 180 YSAYPRTIDFAAFRSIADEVGAFLLADMAHIAGLVAAGVHPSPVPHCDVVTTTTHKTLRG 239 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I R D +F K + AVFP QGGP + IAA A+ Sbjct: 240 PRGGLILCR------------------DAEFAKKFDKAVFPGTQGGPLEHVIAAKAVAFG 281 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + P +K Y QQV+ NA ALA L+ R +V+GGTDNH+VL DLR+ G+TGK + + Sbjct: 282 EALQPSFKTYSQQVVANAGALAEQLISRGINVVSGGTDNHVVLLDLRSIGMTGKVADLLV 341 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI+ NK + + G+R+GT A+TTRG D F +AD + Sbjct: 342 SDVHITANKNTVPFDPESPFVTSGLRLGTAALTTRGFDVDAFREVADVI 390
>Q8R887:GLYA_THETN Serine hydroxymethyltransferase - Thermoanaerobacter tengcongensis| Length = 413 Score = 333 bits (853), Expect = 2e-90 Identities = 183/406 (45%), Positives = 253/406 (62%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + DP++ ++ +E +RQ IELIASENFV RAV++A+G+ LTNKY+EG+PG RYYGG Sbjct: 6 IRKTDPEIAEVILKELNRQRNKIELIASENFVSRAVMEAMGTPLTNKYAEGYPGRRYYGG 65 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D E L +R FG + A NVQP+S AN+A Y LL P D ++G++ Sbjct: 66 CEYVDMAEELARERLKKLFGAEHA----NVQPHSGAQANMAAYFALLKPGDTVLGMDLAH 121 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG KV+ + + +SY V TGYIDYD++ED A PK+++ G S+ Sbjct: 122 GGHLTHG------SKVNFSGQIYNFVSYGVREDTGYIDYDQVEDLAKKHKPKLIVAGASA 175 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF + R IADK GA LM DMAHI+GLVAA +P Y DVVT+TTHK LRGPRG Sbjct: 176 YPRIIDFKKFREIADKVGAYLMVDMAHIAGLVAAGLHPNPVPYADVVTTTTHKTLRGPRG 235 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G I ++ + I+ A+FP QGGP + IAA A+ K+ Sbjct: 236 GAILCKQ-------------------EHAKAIDKALFPGTQGGPLMHIIAAKAVCFKEAL 276 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 + E+K Y +++++NA+ALA+AL+ R LV+GGTDNHL+L DLR G+TGK E + Sbjct: 277 SDEFKEYQKRIVENAKALANALMERGINLVSGGTDNHLMLLDLRNTGITGKELETRLDEV 336 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK I + G GVR+GTPA+TTRG +D IAD + Sbjct: 337 NITCNKNAIPFDPLGPNVTSGVRLGTPAVTTRGMKPEDMVEIADII 382
>Q6AM21:GLYA_DESPS Serine hydroxymethyltransferase - Desulfotalea psychrophila| Length = 425 Score = 332 bits (851), Expect = 4e-90 Identities = 186/457 (40%), Positives = 268/457 (58%), Gaps = 1/457 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + DP++ +L+++E RQ I LIASEN+V AVL+A GS LTNKYSEG+PG RYY G Sbjct: 13 LQQQDPEIFSLIQQEEVRQHNKIRLIASENYVSSAVLEATGSILTNKYSEGYPGKRYYEG 72 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 Q ID IE + RA FG + VNVQPYS + AN+AVY L P D I+G+ P Sbjct: 73 QQLIDQIESIAIDRAKAVFGAEH----VNVQPYSGSPANMAVYLAFLKPGDTILGMALPH 128 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG KVS + +F ++SY +N + G +DY+++ ++A++ PKILI G S+ Sbjct: 129 GGHLTHG------SKVSISGKYFNAVSYALNEE-GILDYEEIRNKALECKPKILIAGHSA 181 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DFA+ R IAD+ GA+LM DMAH +GLVA SPF Y DVVT+TTHK+LRGPRG Sbjct: 182 YPRILDFAKFREIADEVGALLMVDMAHFAGLVAGGVHPSPFPYADVVTTTTHKSLRGPRG 241 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 +I + ++ I+ AVFP +QGGPH++ AA+A+ LK+ + Sbjct: 242 AMIMCKA-------------------EYAKAIDKAVFPGMQGGPHDSTTAAIAVALKEAS 282 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 T +K Y QV++NA +LA L+ + LVTGGT+NHL+L DL +TGK K + Sbjct: 283 TDSFKKYTAQVVENAASLADVLIEKGFNLVTGGTENHLMLIDLSNKNITGKQAAKALDAA 342 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I +N + + P G+R+GT A+T+RG + + ++ Sbjct: 343 GIVLNCNSVPFDKRKPFDPSGIRLGTCAITSRGFAKAEMVIL------------------ 384 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAMPGFD 1998 G + + E++ + E+ +V+A +F PG + Sbjct: 385 GNMMDRVVNNFEDSAVLAEIAQEVQALCDKFPAPGLE 421
>Q8UG75:GLYA1_AGRT5 Serine hydroxymethyltransferase 1 - Agrobacterium tumefaciens (strain| C58 / ATCC 33970) Length = 429 Score = 330 bits (847), Expect = 1e-89 Identities = 189/413 (45%), Positives = 247/413 (59%), Gaps = 1/413 (0%) Frame = +1 Query: 613 AWGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPG 792 A+ ++PLAE DPD+ +E+E RQ IELIASEN V RAVL+A GS +TNKY+EG+PG Sbjct: 6 AFFSRPLAEVDPDIFGAIEKELGRQRHEIELIASENIVSRAVLEAQGSIMTNKYAEGYPG 65 Query: 793 ARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIM 972 RYYGG Q +D E L +RA FG++ A NVQP S + N AV+ LL P D M Sbjct: 66 KRYYGGCQFVDIAEELAIERAKKLFGVNFA----NVQPNSGSQMNQAVFLALLQPGDTFM 121 Query: 973 GLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKIL 1152 GL+ SGGH++HG V+ + +F +SY V +D D++E +A + PK++ Sbjct: 122 GLDLNSGGHLTHG------SPVNMSGKWFNVVSYGVREGDNLLDMDEVERKAKETRPKLI 175 Query: 1153 ICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKN 1332 + GG++Y R WD+ R R IAD+ GA LM DMAHI+GLVA + SPF +C V T+TTHK+ Sbjct: 176 LAGGTAYSRVWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPFPHCHVATTTTHKS 235 Query: 1333 LRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAI 1512 LRGPRGG+I ND D K N AVFP LQGGP + IAA A+ Sbjct: 236 LRGPRGGMIL------------------TNDEDLAKKFNSAVFPGLQGGPLMHVIAAKAV 277 Query: 1513 TLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFE 1692 + PE+K Y QV+KNA+ALA L+ +V+GGTDNHL+L DLR TGK E Sbjct: 278 AFGEALQPEFKDYAAQVVKNAKALAETLIEGGLDVVSGGTDNHLMLVDLRKKNATGKRAE 337 Query: 1693 KVCELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 +I+ NK I + GVR+GTPA TTRG E +F I ++ Sbjct: 338 AALGRAYITCNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFKEAEFREIGKLIV 390
>Q8DH33:GLYA_SYNEL Serine hydroxymethyltransferase - Synechococcus elongatus| (Thermosynechococcus elongatus) Length = 425 Score = 330 bits (845), Expect = 2e-89 Identities = 190/406 (46%), Positives = 250/406 (61%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + DP V +++RE RQ + +ELIASENF AV+ A G+ LTNKY+EG PG RYYGG Sbjct: 7 LVQTDPLVAEMVQREVQRQQQHLELIASENFTSPAVMAAQGTVLTNKYAEGLPGKRYYGG 66 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D +E+L RA FG A NVQP+S AN AV+ LL P D IMG++ Sbjct: 67 CEFVDEVEQLAIDRAKELFGAAHA----NVQPHSGAQANFAVFLALLNPGDTIMGMDLSH 122 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S VSG +F + Y V+P+T +D D++ D A PK++ICG S+ Sbjct: 123 GGHLTHG----SPVNVSGK--WFNVVHYGVHPETERLDMDQVRDLARQHRPKLIICGYSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR FA R IAD+ GA LM D+AHI+GLVA+ +P CDVVT+TTHK LRGPRG Sbjct: 177 YPRVIPFAEFRQIADEVGAYLMADIAHIAGLVASGYHPNPVPLCDVVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D D K++ AVFP QGGP + IAA A+ + Sbjct: 237 GLILTR------------------DEDLGKKLDKAVFPGTQGGPLEHVIAAKAVAFGEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+KAY QV++NAQALA+ L R+ RLV+GGTDNHL+L DLR+ LTGK +++ Sbjct: 279 KPEFKAYCGQVIRNAQALAAGLQARQLRLVSGGTDNHLMLIDLRSVNLTGKEADRLMGEI 338 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI+ NK I D S G+R+GTPA+TTRG E +F +A+ + Sbjct: 339 HITTNKNTIPFDPASPFVTSGLRLGTPALTTRGFTEVEFAEVAEII 384
>Q92GH7:GLYA_RICCN Serine hydroxymethyltransferase - Rickettsia conorii| Length = 420 Score = 328 bits (842), Expect = 5e-89 Identities = 198/448 (44%), Positives = 260/448 (58%), Gaps = 2/448 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L E D +++ +++ E+ RQ IELIASENFV AVL+A G+ LTNKY+EG+P R+ Sbjct: 5 NNNLHETDKEINEIIKHEKLRQSSVIELIASENFVSPAVLEAQGALLTNKYAEGYPSKRF 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 Y G + +D E L +R F C NVQP+S + AN AVY LL P D ++G+ Sbjct: 65 YNGCEEVDKAENLAIERVKKLFN----CKYANVQPHSGSQANQAVYLALLQPGDTVLGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFH-PKILIC 1158 SGGH++HG + +SG +F ++SY VN +T IDYD++E R D H PK+LI Sbjct: 121 LDSGGHLTHG----AAPNMSGK--WFNAVSYSVNKETYLIDYDEIE-RLADLHKPKLLIA 173 Query: 1159 GGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLR 1338 G S+YPR DFA+ R I DK GA M D+AHI+GLVA E +SP Y VTSTTHK LR Sbjct: 174 GFSAYPRNIDFAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIPYAHAVTSTTHKTLR 233 Query: 1339 GPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITL 1518 GPRGG+I ND KIN A+FP LQGGP + IAA A+ Sbjct: 234 GPRGGLIL------------------SNDEAIGHKINSALFPGLQGGPLMHIIAAKAVAF 275 Query: 1519 KQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKV 1698 + PEYK+YIQQV+ NA+ALAS+L R ++TGGTDNH+VL DLR G+TGK Sbjct: 276 LENLQPEYKSYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKLAANS 335 Query: 1699 CELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV 1875 + I+ NK I + + G+R+GTPA TTRG E DF ++ Sbjct: 336 LDRAGITCNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLV-------------- 381 Query: 1876 LKQHGKVQKEFLRGLENNKDIIELGNQV 1959 G + + L GL+NN+D L +V Sbjct: 382 ----GHMVADILDGLKNNEDNSALEQKV 405
>Q8A9S7:GLYA_BACTN Serine hydroxymethyltransferase - Bacteroides thetaiotaomicron| Length = 426 Score = 328 bits (840), Expect = 8e-89 Identities = 184/404 (45%), Positives = 249/404 (61%), Gaps = 3/404 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + ++E+E RQ++GIELIASENFV V+ A+GS LTNKY+EG+PG RYYGG + + Sbjct: 4 DDLIFDIIEKEHQRQLKGIELIASENFVSDQVMQAMGSCLTNKYAEGYPGKRYYGGCEVV 63 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E++ R FG + A NVQP+S AN AV+ +L P D+ MGL GGH+ Sbjct: 64 DQSEQIAIDRLKEIFGAEWA----NVQPHSGAQANAAVFLAVLNPGDKFMGLNLAHGGHL 119 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 SHG V+ + I + Y +N +TG +DYD++E+ A+ PK++I GGS+Y RE Sbjct: 120 SHG------SLVNTSGIIYTPCEYNLNQETGRVDYDQMEEVALREKPKMIIGGGSAYSRE 173 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 WD+ RMR IADK GA+LM DMAH +GL+AA +P Y +VTSTTHK LRGPRGG+I Sbjct: 174 WDYKRMREIADKVGAILMIDMAHPAGLIAAGLLENPVKYAHIVTSTTHKTLRGPRGGVIM 233 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 GK+ G + E ++ AVFP +QGGP + IAA A+ ++ PEY Sbjct: 234 M--GKDFPNPWGKKTPKGEIKM-MSQLLDSAVFPGVQGGPLEHVIAAKAVAFGEILQPEY 290 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTF--GLTGKNFEKVCELCHI 1716 K Y +QV KNA LA AL+ R +V+GGTDNH +L DLR+ LTGK EK I Sbjct: 291 KEYAKQVQKNAAILAQALIDRGFTIVSGGTDNHSMLVDLRSKYPDLTGKVAEKALVSADI 350 Query: 1717 SINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 ++NK + + + G+R+GTPA+TTRG ED IA+ + Sbjct: 351 TVNKNMVPFDSRSAFQTSGIRLGTPAITTRGAKEDLMIEIAEMI 394
>P77962:GLYA_SYNY3 Serine hydroxymethyltransferase - Synechocystis sp. (strain PCC 6803)| Length = 427 Score = 327 bits (839), Expect = 1e-88 Identities = 186/406 (45%), Positives = 247/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA +DP + A+++RE RQ IELIASENF AV+ A GS LTNKY+EG PG RYYGG Sbjct: 9 LATSDPALAAIIDRELQRQRTHIELIASENFTSAAVMAAQGSVLTNKYAEGLPGKRYYGG 68 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E L R FG A NVQP+S AN AV+ LL P D IMG++ Sbjct: 69 CEFVDQAETLAISRVKELFGAAHA----NVQPHSGAQANFAVFLTLLQPGDTIMGMDLSH 124 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S VSG +FE Y V +TG +DYDK+ +A++ PK+LICG S+ Sbjct: 125 GGHLTHG----SPVNVSGK--WFEVAHYGVEKETGRLDYDKIRQQALEVKPKLLICGYSA 178 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR+ +F + R IAD+ GA LM D+AHI+GLVA+ SP YCDVVT+TTHK LRGPRG Sbjct: 179 YPRQIEFDKFRAIADEVGAYLMADIAHIAGLVASGHHPSPLPYCDVVTTTTHKTLRGPRG 238 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I N+ + K + +VFP QGGP + I A A+ + Sbjct: 239 GLIM------------------TNNEELGKKFDKSVFPGTQGGPLEHVITAKAVAFGEAL 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QV+ NAQA+A L +R LV+GGTDNHL+L DLR+ +TGK +++ Sbjct: 281 KPEFKVYSGQVIANAQAMADQLQKRGFDLVSGGTDNHLMLVDLRSIAMTGKVGDQLLGEI 340 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK + + G+R+G+PAMTTRG ED+F IA+ + Sbjct: 341 NITANKNTVPFDPESPFVTSGLRLGSPAMTTRGMQEDEFRTIANII 386
>Q74CR5:GLYA_GEOSL Serine hydroxymethyltransferase - Geobacter sulfurreducens| Length = 415 Score = 327 bits (837), Expect = 2e-88 Identities = 182/405 (44%), Positives = 248/405 (61%), Gaps = 1/405 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP V + E +RQ +ELIASENFV AVL+A GS +TNKY+EG+PG RYYGG H+ Sbjct: 8 DPQVAEAIRHETERQEYNLELIASENFVSEAVLEAQGSVMTNKYAEGYPGKRYYGGCHHV 67 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG D A NVQP+S + AN+AVY +L P D I+G+ GGH+ Sbjct: 68 DVVENLAIERAKELFGADHA----NVQPHSGSQANMAVYFSVLKPGDTILGMNLSHGGHL 123 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG V+ + FF + Y V+ +T ID++++E A++ PK+++ G S+YPR Sbjct: 124 THG------SPVNFSGRFFNVVPYGVSQETETIDFNEVERLALEHKPKMIVVGASAYPRT 177 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFA R+IADK GAV+M DMAHI+GLVAA SP Y + VT+TTHK LRGPRGG+I Sbjct: 178 IDFAAFRIIADKVGAVIMVDMAHIAGLVAAGLHPSPVPYAEFVTTTTHKTLRGPRGGMIL 237 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 R+ ++ +N +FP +QGGP + IAA A+ LK+ PE+ Sbjct: 238 CRE-------------------EYAKTLNSNIFPGIQGGPLMHVIAAKAVALKEALQPEF 278 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 KAY Q++KNA+ALA L++R RLV+GGTDNHL+L +L LTGK E+ + I++ Sbjct: 279 KAYQAQIVKNAKALADELVKRGFRLVSGGTDNHLMLVNLTGTELTGKVAEESLDKAGITV 338 Query: 1723 NKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 NK + + G RIGTPA TT G E + +A F+ A Sbjct: 339 NKNTVPFETRSPFVTSGFRIGTPAATTHGLKEAEMADVAGFIAEA 383
>Q4UK96:GLYA_RICFE Serine hydroxymethyltransferase - Rickettsia felis (Rickettsia azadi)| Length = 421 Score = 324 bits (830), Expect = 1e-87 Identities = 197/440 (44%), Positives = 256/440 (58%), Gaps = 2/440 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L E D ++ +++ E+ RQ IELIASENFV AVL+A GS LTNKY+EG+ G R+ Sbjct: 5 NNHLHETDKEIDEIIKHEKLRQNSVIELIASENFVSPAVLEAQGSILTNKYAEGYSGKRF 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 Y G + +D E L +R F C NVQ +S + AN AVY LL P D I+G+ Sbjct: 65 YNGCEEVDKAENLAIERVKKLFN----CKYANVQSHSGSQANQAVYLALLQPGDTILGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFH-PKILIC 1158 SGGH++HG + +SG +F ++SY VN +T IDYD++E R D H PK+LI Sbjct: 121 LDSGGHLTHG----AAPNMSGK--WFNAVSYSVNKETYLIDYDEIE-RLADLHKPKLLIA 173 Query: 1159 GGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLR 1338 G S+YPR DFAR R IADK GA M D+AHI+GLVA E +SP Y VTSTTHK LR Sbjct: 174 GFSAYPRNIDFARFREIADKVGAYFMADIAHIAGLVATGEHQSPIPYTHAVTSTTHKTLR 233 Query: 1339 GPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITL 1518 GPRGG+I ND + KIN A+FP LQGGP + IAA A+ Sbjct: 234 GPRGGLIL------------------SNDEEIGKKINSALFPGLQGGPLMHIIAAKAVAF 275 Query: 1519 KQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKV 1698 + PEYK+YI+QV+ NA+ALAS+L R ++TGGTDNH+VL DL G+TGK Sbjct: 276 LENLQPEYKSYIKQVISNAKALASSLQERGYDILTGGTDNHIVLVDLCKDGITGKLAANS 335 Query: 1699 CELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV 1875 + I+ NK I + + G+R+GTPA TTRG E DF ++ Sbjct: 336 LDRAGITCNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLV-------------- 381 Query: 1876 LKQHGKVQKEFLRGLENNKD 1935 G + + L GL+NN+D Sbjct: 382 ----GHMVADILDGLKNNED 397
>Q1RGX5:GLYA_RICBR Serine hydroxymethyltransferase - Rickettsia bellii (strain RML369-C)| Length = 420 Score = 324 bits (830), Expect = 1e-87 Identities = 193/413 (46%), Positives = 251/413 (60%), Gaps = 5/413 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L E D + +++ E+ RQ IELIASENFV AVL+A GS LTNKY+EG+ G R+ Sbjct: 5 NNKLQEIDKGIFEIIKHEKTRQNSVIELIASENFVSPAVLEAQGSVLTNKYAEGYSGKRF 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 Y G + +D E L +RA F C NVQP+S + AN AVY L+ P D ++G+ Sbjct: 65 YNGCEEVDKAENLAIERAKKLFN----CKYANVQPHSGSQANQAVYLALMQPGDTVLGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 SGGH++HG S +SG +F ++SY V+ +T IDYD++E A+ PK+LI G Sbjct: 121 LDSGGHLTHG----STANMSGK--WFNAVSYSVDKETYLIDYDEVERLAILHKPKLLIAG 174 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR DFA+ R IADK GA LM D+AHI+GLVAA E +SP + +VTSTT+K LRG Sbjct: 175 FSAYPRNLDFAKFREIADKVGAYLMADIAHIAGLVAAGEHQSPIPHAHIVTSTTNKTLRG 234 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I ND + KIN A+FP LQGGP + IAA A+ Sbjct: 235 PRGGLIL------------------SNDEEIGKKINSALFPGLQGGPLMHIIAAKAVAFL 276 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PEYK+YI+QV+ NA+ALA +L R ++TGGTDNH+VL DLR G+TGK Sbjct: 277 ESLQPEYKSYIKQVIINAKALAGSLQERGYDILTGGTDNHIVLVDLRKDGITGKIAANSL 336 Query: 1702 ELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDF----EVIADFL 1845 + I+ NK I D S G+R+GTPA TTRG E DF +IAD L Sbjct: 337 DRAGITCNKNAIPFDKTSPFITSGIRLGTPACTTRGFKEKDFVLVGHLIADIL 389
>Q72IH2:GLYA_THET2 Serine hydroxymethyltransferase - Thermus thermophilus (strain HB27 /| ATCC BAA-163 / DSM 7039) Length = 407 Score = 323 bits (829), Expect = 1e-87 Identities = 180/405 (44%), Positives = 248/405 (61%), Gaps = 1/405 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + L+ E RQ G+ELIASENFV + V +A+GS LTNKY+EG+PGARYYGG + I Sbjct: 8 DEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCEAI 67 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG A W NVQP+S + AN+AVY L+ P D +MG++ +GGH+ Sbjct: 68 DRVESLAIERAKALFG---AAWA-NVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGGHL 123 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG +V+ + ++ +SY V P T ID +++ A++ PK+++ G S+YPR Sbjct: 124 THG------SRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPRF 177 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 WDF R IAD+ GA L+ DMAH +GLVAA +P Y VVTSTTHK LRGPRGG+I Sbjct: 178 WDFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLIL 237 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 ND + +I+ +FP +QGGP + IA A+ + PE+ Sbjct: 238 ------------------SNDPELGKRIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEF 279 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y + V++NA+ LA AL RR R+VTGGTDNHL L DLR GLTGK E+ + I++ Sbjct: 280 KEYSRLVVENAKRLAEALARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITV 339 Query: 1723 NKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 NK I + G+RIGTPA+TTRG ++ ++A+ + RA Sbjct: 340 NKNAIPFDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELIDRA 384
>Q64U78:GLYA_BACFR Serine hydroxymethyltransferase - Bacteroides fragilis| Length = 426 Score = 323 bits (829), Expect = 1e-87 Identities = 183/404 (45%), Positives = 248/404 (61%), Gaps = 3/404 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + ++E+E RQ++GIELIASENFV V++A+GS LTNKY+EG+PG RYYGG + + Sbjct: 4 DDLIFDIIEKEHQRQLKGIELIASENFVSDQVMEAMGSCLTNKYAEGYPGKRYYGGCEVV 63 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E++ R FG + A NVQP+S AN AV+ +L P D+ MGL GGH+ Sbjct: 64 DQSEQIAIDRLKEIFGAEWA----NVQPHSGAQANAAVFLAVLNPGDKFMGLNLAHGGHL 119 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 SHG V+ + I + Y + +TG +DYD++E+ A+ PK++I GGS+Y RE Sbjct: 120 SHG------SLVNTSGIIYTPCEYNLKQETGRVDYDQMEEVALREKPKMIIGGGSAYSRE 173 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 WD+ RMR IADK GA+LM DMAH +GL+AA +P Y +VTSTTHK LRGPRGG+I Sbjct: 174 WDYKRMREIADKVGAILMIDMAHPAGLIAAGLLDNPVKYAHIVTSTTHKTLRGPRGGVIM 233 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 GK+ G + E ++ AVFP +QGGP + IAA A+ + PEY Sbjct: 234 M--GKDFPNPWGKKTPKGEIKM-MSQLLDSAVFPGIQGGPLEHVIAAKAVAFGECLQPEY 290 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTF--GLTGKNFEKVCELCHI 1716 K Y +QV KNA LA AL+ R +V+GGTDNH +L DLR+ LTGK EK I Sbjct: 291 KEYQKQVQKNAAVLAQALIDRGFTIVSGGTDNHSMLVDLRSKYPTLTGKVAEKALVSADI 350 Query: 1717 SINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 ++NK + + + G+R+GTPA+TTRG ED IA+ + Sbjct: 351 TVNKNMVPFDSRSAFQTSGIRLGTPAITTRGAKEDLMLEIAEMI 394
>Q5LD58:GLYA_BACFN Serine hydroxymethyltransferase - Bacteroides fragilis (strain ATCC| 25285 / NCTC 9343) Length = 426 Score = 323 bits (829), Expect = 1e-87 Identities = 183/404 (45%), Positives = 248/404 (61%), Gaps = 3/404 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + ++E+E RQ++GIELIASENFV V++A+GS LTNKY+EG+PG RYYGG + + Sbjct: 4 DDLIFDIIEKEHQRQLKGIELIASENFVSDQVMEAMGSCLTNKYAEGYPGKRYYGGCEVV 63 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E++ R FG + A NVQP+S AN AV+ +L P D+ MGL GGH+ Sbjct: 64 DQSEQIAIDRLKEIFGAEWA----NVQPHSGAQANAAVFLAVLNPGDKFMGLNLAHGGHL 119 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 SHG V+ + I + Y + +TG +DYD++E+ A+ PK++I GGS+Y RE Sbjct: 120 SHG------SLVNTSGIIYTPCEYNLKQETGRVDYDQMEEVALREKPKMIIGGGSAYSRE 173 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 WD+ RMR IADK GA+LM DMAH +GL+AA +P Y +VTSTTHK LRGPRGG+I Sbjct: 174 WDYKRMREIADKVGAILMIDMAHPAGLIAAGLLDNPVKYAHIVTSTTHKTLRGPRGGVIM 233 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 GK+ G + E ++ AVFP +QGGP + IAA A+ + PEY Sbjct: 234 M--GKDFPNPWGKKTPKGEIKM-MSQLLDSAVFPGIQGGPLEHVIAAKAVAFGECLQPEY 290 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTF--GLTGKNFEKVCELCHI 1716 K Y +QV KNA LA AL+ R +V+GGTDNH +L DLR+ LTGK EK I Sbjct: 291 KEYQKQVQKNAAVLAQALIDRGFTIVSGGTDNHSMLVDLRSKYPTLTGKVAEKALVSADI 350 Query: 1717 SINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 ++NK + + + G+R+GTPA+TTRG ED IA+ + Sbjct: 351 TVNKNMVPFDSRSAFQTSGIRLGTPAITTRGAKEDLMLEIAEMI 394
>Q3A4L9:GLYA_PELCD Serine hydroxymethyltransferase - Pelobacter carbinolicus (strain DSM| 2380 / Gra Bd 1) Length = 416 Score = 323 bits (827), Expect = 2e-87 Identities = 183/456 (40%), Positives = 259/456 (56%), Gaps = 1/456 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +Q L + DP++ + E +RQ +E IASENFV V++A GS +TNKY+EG+P RY Sbjct: 2 SQTLIQQDPEIAEAIRLETERQEYNLEFIASENFVSEQVMEAQGSIMTNKYAEGYPAKRY 61 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + +D ERL +RA FG + A NVQ +S + AN+AVY P D ++G+ Sbjct: 62 YGGCEMVDIAERLAIERAKELFGAEHA----NVQAHSGSQANMAVYFAACKPGDTVLGMN 117 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG V+ + F +SY V +TGYIDY+++E A++ P +L+ G Sbjct: 118 LAHGGHLTHG------SPVNFSGKLFNIVSYGVQKETGYIDYEEVERLALEHKPTLLVVG 171 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR DF R IADK GA +M DMAHI+GLVAA SP Y + VT+TTHK LRG Sbjct: 172 ASAYPRTIDFPAFRKIADKVGAKIMVDMAHIAGLVAAGVHPSPVPYAEFVTTTTHKTLRG 231 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I R+ +F I+ +FP +QGGP + IAA A++ K Sbjct: 232 PRGGMILCRE-------------------EFAKTIDSNIFPGIQGGPLMHVIAAKAVSFK 272 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+K Y QV+KNA+ LA AL++R LV+GGTDNHL+L D TGK EK Sbjct: 273 EALAPEFKEYSTQVVKNAKVLADALVKRGLNLVSGGTDNHLILVDFTGTETTGKMAEKAL 332 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVL 1878 E I++NK + + G+R+GTPA TTRG E + E +AD+++RA Sbjct: 333 EKAGITVNKNSVPFETRSPFVTSGIRLGTPATTTRGLKEAEMERVADWVVRA-------- 384 Query: 1879 KQHGKVQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 L +EN+ ++ + +V +F + Sbjct: 385 ----------LDNMENDTELAAIKGEVREMCKRFPL 410
>O08370:GLYA_RICPR Serine hydroxymethyltransferase - Rickettsia prowazekii| Length = 420 Score = 322 bits (826), Expect = 3e-87 Identities = 196/439 (44%), Positives = 257/439 (58%), Gaps = 1/439 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L E D +++ +++ E+ RQ IELIASENFV AVL+A GS LTNKY+EG+P R+ Sbjct: 5 NNNLYEMDKEIYEIIKNEKIRQNNVIELIASENFVSSAVLEAQGSILTNKYAEGYPSKRF 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 Y G +D E L +R F C NVQP+S + AN VY LL P D I+G+ Sbjct: 65 YNGCDEVDKAEVLAIERIKKLFN----CKYANVQPHSGSQANQTVYLALLQPCDTILGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 SGGH++HG + +SG +F ++SY V+ +T IDYD++E A+ +PK+LI G Sbjct: 121 LDSGGHLTHG----AAPNISGK--WFNTVSYHVDQETYLIDYDEVERLAVLHNPKLLIAG 174 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR+ DFA+ R IADK GA LM D+AHI+GLVA E +SP Y VVTSTTHK LRG Sbjct: 175 FSAYPRKIDFAKFRKIADKVGAYLMADIAHIAGLVATGEHQSPIPYAHVVTSTTHKTLRG 234 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I +D + KIN A+FP LQGGP + IAA A+ Sbjct: 235 PRGGLIL------------------SDDEEIGKKINSALFPGLQGGPLMHIIAAKAVAFL 276 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PEYK YI+QV+ NA+ALA +L R ++TGGTDNH+VL DLR G+TGK Sbjct: 277 ENLQPEYKNYIKQVISNAKALAISLQERGYDILTGGTDNHIVLVDLRKDGITGKCAANSL 336 Query: 1702 ELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVL 1878 + I+ NK I D S G+R GTPA TT+G E DF +I Sbjct: 337 DRAGITCNKNAIPFDTTSPFITSGIRFGTPACTTKGFKEKDFVLI--------------- 381 Query: 1879 KQHGKVQKEFLRGLENNKD 1935 G + E L GL++N+D Sbjct: 382 ---GHMVAEILDGLKHNED 397
>Q39V87:GLYA_GEOMG Serine hydroxymethyltransferase - Geobacter metallireducens (strain| GS-15 / ATCC 53774 / DSM 7210) Length = 415 Score = 322 bits (825), Expect = 4e-87 Identities = 180/414 (43%), Positives = 248/414 (59%), Gaps = 1/414 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP V + E +RQ +ELIASENFV AV++A GS LTNKY+EG+PG RYYGG H+ Sbjct: 8 DPAVAEAIRHETERQEYNLELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCHHV 67 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG D A NVQP+S + AN+AVY +L P D I+G+ GGH+ Sbjct: 68 DVVENLAIERAKELFGADHA----NVQPHSGSQANMAVYFSVLKPGDTILGMNLSHGGHL 123 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG V+ + FF + Y V+ +T ID++++E A++ PK+++ G S+YPR Sbjct: 124 THG------SPVNFSGRFFNVVPYGVSQETETIDFNEVERLALEHKPKLIVVGASAYPRV 177 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFA R IADK GA++M DMAHI+GLVAA SP Y + VT+TTHK LRGPRGG+I Sbjct: 178 LDFAAFRAIADKVGALVMVDMAHIAGLVAAGLHPSPVPYAEFVTTTTHKTLRGPRGGMIL 237 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 R+ +F +N +FP +QGGP + IAA A+ K+ PE+ Sbjct: 238 CRE-------------------EFAKTLNSNIFPGIQGGPLMHVIAAKAVAFKEALAPEF 278 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y +Q++KNA+ LA L++R RLV+GGTDNHL+L +L LTGK E+ + I++ Sbjct: 279 KLYQEQIVKNARTLADELMKRGFRLVSGGTDNHLMLVNLTGTELTGKVAEEALDKAGITV 338 Query: 1723 NKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLK 1881 NK + + G RIGTPA T+ G E + +A F+ A G+ K Sbjct: 339 NKNTVPFETRSPFVTSGFRIGTPAATSHGLKEAEMVEVAAFIAEALANVGNEAK 392
>Q7V4U3:GLYA_PROMM Serine hydroxymethyltransferase - Prochlorococcus marinus (strain MIT| 9313) Length = 429 Score = 322 bits (824), Expect = 6e-87 Identities = 185/409 (45%), Positives = 247/409 (60%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L ++DP + L+++ER RQ +ELIASENF +AV+ A GS LTNKY+EG P RY Sbjct: 10 NAALTDSDPAIAGLIDQERQRQETHLELIASENFTSQAVMQAQGSVLTNKYAEGLPHKRY 69 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +H+DAIE L +RA FG A W NVQP+S AN AV+ LL P D IMG++ Sbjct: 70 YGGCEHVDAIEELAIERAQRLFG---AAWA-NVQPHSGAQANFAVFLALLQPGDTIMGMD 125 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG S VSG +F+ + Y V + +D + + A+ P+++ICG Sbjct: 126 LSHGGHLTHG----SPVNVSGK--WFKVVHYGVERDSQQLDMEAVRQLALKERPQLIICG 179 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR DFA R IAD+ GA L+ DMAHI+GLVAA SP +CDVVT+TTHK LRG Sbjct: 180 YSAYPRTIDFAAFRSIADEVGAYLLADMAHIAGLVAAGVHPSPIAHCDVVTTTTHKTLRG 239 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I R D DF K + AVFP QGGP + IAA A+ L Sbjct: 240 PRGGLILCR------------------DADFGRKFDKAVFPGSQGGPLEHVIAAKAVALG 281 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE++ Y QV+ NAQ LA + R +V+GGTDNHLVL DLR+ G+TGK + + Sbjct: 282 EALQPEFQVYSCQVVANAQVLAGRIQERGIAVVSGGTDNHLVLLDLRSIGMTGKVADLLV 341 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK + + G+R+GT A+TTRG ++ F +AD + Sbjct: 342 SEVNITANKNTVPFDPESPFVTSGLRLGTAALTTRGFDDEAFREVADVI 390
>Q5SI56:GLYA_THET8 Serine hydroxymethyltransferase - Thermus thermophilus (strain HB8 /| ATCC 27634 / DSM 579) Length = 407 Score = 321 bits (823), Expect = 7e-87 Identities = 179/405 (44%), Positives = 247/405 (60%), Gaps = 1/405 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + L+ E RQ G+ELIASENFV + V +A+GS LTNKY+EG+PGARYYGG + I Sbjct: 8 DEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCEVI 67 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG A W NVQP+S + AN+AVY L+ P D +MG++ +GGH+ Sbjct: 68 DRVESLAIERAKALFG---AAWA-NVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGGHL 123 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG +V+ + ++ +SY V P T ID +++ A++ PK+++ G S+YPR Sbjct: 124 THG------SRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPRF 177 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 WDF R IAD+ GA L+ DMAH +GLVAA +P Y VVTSTTHK LRGPRGG+I Sbjct: 178 WDFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLIL 237 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 ND + +I+ +FP +QGGP + IA A+ + PE+ Sbjct: 238 ------------------SNDPELGKRIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEF 279 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y + V++NA+ LA L RR R+VTGGTDNHL L DLR GLTGK E+ + I++ Sbjct: 280 KEYSRLVVENAKRLAEELARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITV 339 Query: 1723 NKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 NK I + G+RIGTPA+TTRG ++ ++A+ + RA Sbjct: 340 NKNAIPFDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELIDRA 384
>Q2JT50:GLYA_SYNJA Serine hydroxymethyltransferase - Synechococcus sp. (strain JA-3-3Ab)| (Cyanobacteria bacterium Yellowstone A-Prime) Length = 434 Score = 321 bits (823), Expect = 7e-87 Identities = 194/418 (46%), Positives = 248/418 (59%), Gaps = 13/418 (3%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LAE DP V+ L+++E +RQ +E+IASENF AVL A GS LTNKY+EG PG RYYGG Sbjct: 11 LAETDPVVYRLIQQELNRQRDHLEMIASENFTSPAVLAAQGSVLTNKYAEGLPGKRYYGG 70 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + ID IE+L RA FG A NVQP+S AN AV+ LL P D IMG++ Sbjct: 71 CEFIDEIEQLAIDRAKQLFGAAHA----NVQPHSGAQANFAVFLALLQPGDTIMGMDLAH 126 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S VSG +F + Y V+PQT ID+D++ D A PK++ICG S+ Sbjct: 127 GGHLTHG----SPVNVSGK--WFRVVHYGVDPQTERIDFDQVRDLARQHRPKLIICGYSA 180 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DFA R IAD+ GA LM D+AHI+GLVA +P CDVVT+TTHK LRGPRG Sbjct: 181 YPRIIDFAAFRAIADEVGAYLMADIAHIAGLVATGHHPNPVPICDVVTTTTHKTLRGPRG 240 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D + K++ AVFP QGGP + IA A+ + Sbjct: 241 GLILTR------------------DPELGKKLDKAVFPGSQGGPLEHVIAGKAVAFGEAL 282 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFG------------L 1674 P + Y QV+ NAQALA+ L RR RLV+GGTDNHLVL DLR+ + Sbjct: 283 QPSFAQYSAQVIANAQALAATLQRRGIRLVSGGTDNHLVLLDLRSVSAVLEKNGAADPVM 342 Query: 1675 TGKNFEKVCELCHISINKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 TGK +++ E HI+ NK I D S G+R+G+PA+TTRG +FE I + + Sbjct: 343 TGKRADRLMEEIHITANKNTIPFDPQPPSVASGLRLGSPALTTRGLGPAEFEEIGEII 400
>Q2S4G9:GLYA_SALRD Serine hydroxymethyltransferase - Salinibacter ruber (strain DSM| 13855) Length = 432 Score = 321 bits (822), Expect = 9e-87 Identities = 179/411 (43%), Positives = 246/411 (59%), Gaps = 1/411 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L DP++H ++++E RQ G+ELIASENF RAV++A+G+ LTNKY+EG PG RYYGG Sbjct: 4 LRNQDPEIHDVIQKEVQRQNDGLELIASENFASRAVMEAMGTALTNKYAEGLPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E L +RA + D W VNVQP++ AN AVY LL P D +GL+ Sbjct: 64 CEVVDRAEELARERAKELYDCD---W-VNVQPHAGAQANSAVYLTLLDPGDTFLGLDLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + I +E+ Y V +TG ID +++ DRA + PK++ G S+ Sbjct: 120 GGHLTHG------SPVNFSGILYEAEYYGVEEETGRIDMNRVRDRAKEVQPKMISIGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR++D+ R IAD+ GA L DMAH +GL+A P + VVT+TTHK LRGPRG Sbjct: 174 YPRDFDYEAFREIADEVGAFLWMDMAHTAGLIAGGVLNDPMPHTHVVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I G + G ++ + ++ AVFP QGGP + IAA A+ K+ Sbjct: 234 GMILL--GDDYENPMGKTARKSGRTKMMSELLDSAVFPGTQGGPLMHVIAAKAVGFKEAL 291 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P + Y QQV+ NAQA+ + L R LV+ GTDNHLVL DLR GLTGK E+ E Sbjct: 292 KPSFAEYTQQVVDNAQAMGAELRERGYDLVSDGTDNHLVLIDLRNKGLTGKEAEQALEAA 351 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 I+ NK + + D G+R+GTPAMTTRG D+F +A+ + R Q Sbjct: 352 GITANKNMVPFDDKSPFVTSGLRLGTPAMTTRGFGPDEFAHVAEMIDRVLQ 402
>Q7W1I6:GLYA1_BORPA Serine hydroxymethyltransferase 1 - Bordetella parapertussis| Length = 430 Score = 321 bits (822), Expect = 9e-87 Identities = 182/408 (44%), Positives = 248/408 (60%), Gaps = 1/408 (0%) Frame = +1 Query: 628 PLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYG 807 PL ADP++ ++ ER RQ+ IELIASENFV +AVLDA GS +TNKY+EG+PG RYYG Sbjct: 18 PLRHADPEIWRAVDAERQRQMHSIELIASENFVSQAVLDAQGSVMTNKYAEGYPGRRYYG 77 Query: 808 GNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPP 987 G +H+D ER +RA FG C NVQP+S + AN AVY LL P DRI+GL+ Sbjct: 78 GCRHVDVAERAAIERARRLFG----CEYANVQPHSGSQANQAVYLALLAPGDRILGLDLK 133 Query: 988 SGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 +GGH++HG +V+ + +FE+LSY V+P + ID D++E A P+++I GGS Sbjct: 134 AGGHLTHG------ARVNLSGKWFEALSYGVDPVSHRIDMDEVERTARRERPRLIIAGGS 187 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 +Y R DFAR R IAD GA+ + DMAH +GLVA SP + V T+TTHK LRGPR Sbjct: 188 AYARVPDFARFRAIADATGALFVADMAHYAGLVAGGAFPSPVPFAHVTTTTTHKTLRGPR 247 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 GG+I +D D +I+ AVFP LQGGP + IAA A+ L + Sbjct: 248 GGMIL------------------TDDADIARRIDAAVFPGLQGGPLMHVIAAKAVALGEA 289 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 P ++AY + V+ NA+AL + L +V+GGTD HL + DLR +GL G E+ E Sbjct: 290 LQPGFRAYARAVIDNARALCARLAEGGLSIVSGGTDCHLGVVDLRPWGLAGNAAERALEE 349 Query: 1708 CHISINKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 I++NK + GD S + G+R+G+ A T+RG +F I D ++ Sbjct: 350 AGITVNKNAVPGDAASPAVTSGIRVGSAACTSRGMGPAEFRQIGDLVL 397
>Q7WPH6:GLYA1_BORBR Serine hydroxymethyltransferase 1 - Bordetella bronchiseptica| (Alcaligenes bronchisepticus) Length = 430 Score = 321 bits (822), Expect = 9e-87 Identities = 184/409 (44%), Positives = 248/409 (60%), Gaps = 2/409 (0%) Frame = +1 Query: 628 PLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYG 807 PL ADP++ ++ ER RQ+ IELIASENFV +AVLDA GS +TNKY+EG+PG RYYG Sbjct: 18 PLRHADPEIWRAVDAERQRQMHSIELIASENFVSQAVLDAQGSVMTNKYAEGYPGRRYYG 77 Query: 808 GNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPP 987 G +H+D ER +RA FG C NVQP+S + AN AVY LL P DRI+GL+ Sbjct: 78 GCRHVDVAERAAIERARRLFG----CEYANVQPHSGSQANQAVYLALLAPGDRILGLDLK 133 Query: 988 SGGHVSHGYYTP-SGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 +GGH++HG + SGK +FE+LSY V+P + ID D++E A P+++I GG Sbjct: 134 AGGHLTHGAHVNLSGK-------WFEALSYGVDPVSHRIDMDEVERTARRERPRLIIAGG 186 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S+Y R DFAR R IAD GA+ + DMAH +GLVA SP + V T+TTHK LRGP Sbjct: 187 SAYARVPDFARFRAIADATGALFVADMAHYAGLVAGGAFPSPVPFAHVTTTTTHKTLRGP 246 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 RGG+I +D D +I+ AVFP LQGGP + IAA A+ L + Sbjct: 247 RGGMIL------------------TDDADIARRIDAAVFPGLQGGPLMHVIAAKAVALGE 288 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 P ++AY + V+ NA+AL + L +V+GGTD HL + DLR +GL G E+ E Sbjct: 289 ALQPGFRAYARAVIDNARALCARLAEGGLSIVSGGTDCHLGVVDLRPWGLAGNAAERALE 348 Query: 1705 LCHISINKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 I++NK + GD S + G+R+G+ A T+RG +F I D ++ Sbjct: 349 EAGITVNKNAVPGDAASPAVTSGIRVGSAACTSRGMGPAEFRQIGDLVL 397
>Q5LPA8:GLYA_SILPO Serine hydroxymethyltransferase - Silicibacter pomeroyi| Length = 431 Score = 320 bits (820), Expect = 2e-86 Identities = 184/410 (44%), Positives = 241/410 (58%), Gaps = 2/410 (0%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 + L+E DP++ + E RQ IELIASEN V AV+ A GS +TNKY+EG+PG RYY Sbjct: 13 EALSERDPELFGAITSELGRQRDEIELIASENIVSAAVMQAQGSVMTNKYAEGYPGRRYY 72 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG Q++D E L +RA FG C NVQP S + AN V+ L+ P D I+G+ Sbjct: 73 GGCQYVDIAENLAIERAKQLFG----CGFANVQPNSGSQANQGVFQALIKPGDTILGMSL 128 Query: 985 PSGGHVSHGYY-TPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 +GGH++HG SGK +F ++ Y V Q +DYD++E A + PK++I G Sbjct: 129 DAGGHLTHGAAPNQSGK-------WFNAVQYGVRQQDNLLDYDQVEALAKEHRPKLIIAG 181 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 GS+ PR+ DFARMR IAD GA L DMAH +GLVAA E SPF + V T+TTHK LRG Sbjct: 182 GSAIPRQIDFARMREIADMVGAYLHVDMAHFAGLVAAGEHPSPFPHAHVATTTTHKTLRG 241 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I ND D K+N A+FP +QGGP + IAA A+ Sbjct: 242 PRGGMIL------------------TNDEDIAKKVNSAIFPGIQGGPLMHVIAAKAVAFG 283 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+K YIQQV+ NAQAL+ L++ VT GTD H+VL DLR G+ G EK Sbjct: 284 EALRPEFKTYIQQVIANAQALSDQLIKGGLDTVTHGTDTHVVLVDLRPKGVKGNATEKAL 343 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 HI+ NK + + G+R+G+PA TTRG E +F IAD++I Sbjct: 344 GRAHITCNKNGVPFDPEKPTVTSGIRLGSPAGTTRGFAETEFRQIADWII 393
>Q31RK5:GLYA_SYNP7 Serine hydroxymethyltransferase - Synechococcus sp. (strain PCC 7942)| (Anacystis nidulans R2) Length = 427 Score = 320 bits (819), Expect = 2e-86 Identities = 183/406 (45%), Positives = 244/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DP + A++ RE RQ +ELIASENF AV+ A GS LTNKY+EG P RYYGG Sbjct: 9 LAQGDPAIAAIIGRELQRQQEHLELIASENFASPAVMAAQGSVLTNKYAEGLPSKRYYGG 68 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E L +RA FG A NVQP+S AN AV+ LL P D +G++ Sbjct: 69 CEFVDQAEELAIERAKELFGAAHA----NVQPHSGAQANFAVFLTLLQPGDTFLGMDLSH 124 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S VSG +F + Y VN +T +DYD + + A+ PK++ICG S+ Sbjct: 125 GGHLTHG----SPVNVSGK--WFNAGHYGVNRETERLDYDAIRELALQHRPKLIICGYSA 178 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DFA+ R IAD+ GA L+ DMAHI+GLVAA SP +CDVVT+TTHK LRGPRG Sbjct: 179 YPRTIDFAKFREIADEVGAYLLADMAHIAGLVAAGLHPSPIPHCDVVTTTTHKTLRGPRG 238 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D + K++ +VFP QGGP + IAA A+ + Sbjct: 239 GLILTR------------------DAELGKKLDKSVFPGTQGGPLEHVIAAKAVAFGEAL 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QV+ NAQALA L R ++V+ GTDNHL+L DLR+ G+TGK + + Sbjct: 281 RPEFKTYSAQVIANAQALARQLQARGLKIVSDGTDNHLLLVDLRSIGMTGKVADLLVSDV 340 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK + + G+R+GT AMTTRG E +F ++AD + Sbjct: 341 NITANKNTVPFDPESPFVTSGIRLGTAAMTTRGFKEAEFAIVADII 386
>Q5N2P9:GLYA_SYNP6 Serine hydroxymethyltransferase - Synechococcus sp. (strain ATCC| 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) Length = 427 Score = 320 bits (819), Expect = 2e-86 Identities = 183/406 (45%), Positives = 244/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DP + A++ RE RQ +ELIASENF AV+ A GS LTNKY+EG P RYYGG Sbjct: 9 LAQGDPAIAAIIGRELQRQQEHLELIASENFASPAVMAAQGSVLTNKYAEGLPSKRYYGG 68 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E L +RA FG A NVQP+S AN AV+ LL P D +G++ Sbjct: 69 CEFVDQAEELAIERAKELFGAAHA----NVQPHSGAQANFAVFLTLLQPGDTFLGMDLSH 124 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S VSG +F + Y VN +T +DYD + + A+ PK++ICG S+ Sbjct: 125 GGHLTHG----SPVNVSGK--WFNAGHYGVNRETERLDYDAIRELALQHRPKLIICGYSA 178 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DFA+ R IAD+ GA L+ DMAHI+GLVAA SP +CDVVT+TTHK LRGPRG Sbjct: 179 YPRTIDFAKFREIADEVGAYLLADMAHIAGLVAAGLHPSPIPHCDVVTTTTHKTLRGPRG 238 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D + K++ +VFP QGGP + IAA A+ + Sbjct: 239 GLILTR------------------DAELGKKLDKSVFPGTQGGPLEHVIAAKAVAFGEAL 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QV+ NAQALA L R ++V+ GTDNHL+L DLR+ G+TGK + + Sbjct: 281 RPEFKTYSAQVIANAQALARQLQARGLKIVSDGTDNHLLLVDLRSIGMTGKVADLLVSDV 340 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK + + G+R+GT AMTTRG E +F ++AD + Sbjct: 341 NITANKNTVPFDPESPFVTSGIRLGTAAMTTRGFKEAEFAIVADII 386
>Q68W07:GLYA_RICTY Serine hydroxymethyltransferase - Rickettsia typhi| Length = 420 Score = 320 bits (819), Expect = 2e-86 Identities = 197/440 (44%), Positives = 258/440 (58%), Gaps = 2/440 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L D +++ +++ E+ RQ IELIASENFV AVL+A GS LTNKY+EG+P R+ Sbjct: 5 NNNLYGMDKEIYEIIKNEKLRQNNVIELIASENFVSSAVLEAQGSILTNKYAEGYPSKRF 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 Y G +D E L +RA F C NVQP+S + AN AVY LL P D I+G+ Sbjct: 65 YNGCDEVDKAEVLAIERAKKLFN----CKYANVQPHSGSQANQAVYLALLQPCDTILGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 SGGH++HG + +SG +F +++Y V+ +T IDYD+++ A+ +PK+LI G Sbjct: 121 LDSGGHLTHG----AAPNISGK--WFNTVAYNVDKETYLIDYDEIKRLAVLHNPKLLIAG 174 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR+ DFAR R IADK GA LM D+AHI+GLVA E +SP Y VVTSTTHK LRG Sbjct: 175 FSAYPRKIDFARFREIADKVGAYLMADIAHIAGLVATGEHQSPIPYAHVVTSTTHKTLRG 234 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDY-DFEDKINFAVFPSLQGGPHNNHIAALAITL 1518 PRGG+I +DY + KIN A+FP LQGGP + IAA A+ Sbjct: 235 PRGGLIL-------------------SDYEEIGKKINSALFPGLQGGPLMHVIAAKAVAF 275 Query: 1519 KQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKV 1698 + PEYK YI+QV+ NA+ALA +L R ++TGGTDNH+VL DLR G+TGK Sbjct: 276 LENLQPEYKCYIKQVISNAKALAISLQERGYDILTGGTDNHIVLVDLRKDGITGKCAANS 335 Query: 1699 CELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV 1875 + I+ NK I D S G+R GT A TT+G E DF +I Sbjct: 336 LDRAGITCNKNAIPFDTTSPFVTSGIRFGTSACTTKGFKEKDFVLI-------------- 381 Query: 1876 LKQHGKVQKEFLRGLENNKD 1935 G + E L GL+NN+D Sbjct: 382 ----GHMVAEILDGLKNNED 397
>Q3K5K9:GLYA3_PSEPF Serine hydroxymethyltransferase 3 - Pseudomonas fluorescens (strain| PfO-1) Length = 417 Score = 320 bits (819), Expect = 2e-86 Identities = 179/389 (46%), Positives = 238/389 (61%), Gaps = 1/389 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + A M E RQ IELIASEN+ + V+ A GS LTNKY+EG+PG RYYGG +H+ Sbjct: 12 DDALLAAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG D A NVQP+S +SAN AVY LL D I+G+ GGH+ Sbjct: 72 DKVEALAIERAKQLFGADYA----NVQPHSGSSANSAVYLALLQAGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KVS + + ++ Y ++ +TG IDYD++E A++ PK+++ G S+Y + Sbjct: 128 THG------AKVSSSGKLYNAVQYGIDTKTGLIDYDEVERLAVECKPKMIVAGFSAYSKT 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF R R IADK GA+L DMAH++GLVAA +P Y DVVT+TTHK LRGPRGG+I Sbjct: 182 LDFPRFRQIADKVGALLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 + + + E K+N AVFP QGGP + IA A+ K+ P + Sbjct: 242 AKANE-----------------EIEKKLNAAVFPGAQGGPLMHVIAGKAVCFKEALEPGF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 KAY QQV+ NAQA+AS ++R +V+GGTDNHL L L GLTGK+ + HI++ Sbjct: 285 KAYQQQVIDNAQAMASVFIKRGYDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRG 1806 NK + D S G+RIGTPA+TTRG Sbjct: 345 NKNAVPNDPQSPFVTSGLRIGTPAVTTRG 373
>Q9WZH9:GLYA_THEMA Serine hydroxymethyltransferase - Thermotoga maritima| Length = 427 Score = 319 bits (818), Expect = 3e-86 Identities = 182/424 (42%), Positives = 252/424 (59%), Gaps = 1/424 (0%) Frame = +1 Query: 637 EADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQ 816 + DP+++ ++ E RQ G+ELIASENF AV++ +GS LTNKY+EG+P RYYGG + Sbjct: 7 QVDPEIYEVLVNELKRQEYGLELIASENFASLAVIETMGSMLTNKYAEGYPKKRYYGGCE 66 Query: 817 HIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGG 996 +D E +RA FG A NVQP+S + AN+AVY L P D IMG+ GG Sbjct: 67 WVDRAEERAIERAKRLFGAKFA----NVQPHSGSQANMAVYLALAQPGDTIMGMSLSHGG 122 Query: 997 HVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYP 1176 H++HG V+ + F+ + Y VN +T IDYD++ A++ PKI++ GGS+Y Sbjct: 123 HLTHG------APVNFSGKIFKVVPYGVNLETETIDYDEVRRLALEHKPKIIVAGGSAYA 176 Query: 1177 REWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGI 1356 R DF R R IAD+ GA LM DMAH +GLVAA +P +Y VVTSTTHK LRGPRGG+ Sbjct: 177 RIIDFKRFREIADEVGAYLMVDMAHFAGLVAAGIHPNPLEYAHVVTSTTHKTLRGPRGGL 236 Query: 1357 IFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATP 1536 I ND + ++ +FP +QGGP + IAA A+ K+ T Sbjct: 237 IL------------------TNDPEIAKAVDKTIFPGIQGGPLMHVIAAKAVCFKEAMTE 278 Query: 1537 EYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHI 1716 E+K Y +QV+KNA+ +A +R R+V+GGTD HL L DL +TGK EK E C I Sbjct: 279 EFKEYQKQVVKNAKKMAEEFQKRGYRIVSGGTDTHLFLVDLTPKDITGKAAEKALESCGI 338 Query: 1717 SINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQHGK 1893 ++NK I + S G+RIGTPA+TTRG E++ E IA+ + + +V+ ++G Sbjct: 339 TVNKNTIPNEKRSPFVASGIRIGTPAVTTRGMKEEEMEEIAEMI---DLVLSNVIDENGT 395 Query: 1894 VQKE 1905 V+ E Sbjct: 396 VKPE 399
>Q5KUI2:GLYA_GEOKA Serine hydroxymethyltransferase - Geobacillus kaustophilus| Length = 412 Score = 319 bits (818), Expect = 3e-86 Identities = 187/424 (44%), Positives = 255/424 (60%), Gaps = 1/424 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + DP V A +E+ER RQ IELIASENFV RAV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 LPQQDPQVFAAIEQERKRQHAKIELIASENFVSRAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E L +RA FG + VNVQP+S AN+AVY +L D ++G+ Sbjct: 64 CEYVDIVEDLARERAKQLFGAEH----VNVQPHSGAQANMAVYFTVLEHGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + I + + Y V+P+T IDYD + ++A PK+++ G S+ Sbjct: 120 GGHLTHG------SPVNFSGIQYNFVEYGVDPETHVIDYDDVREKARLHRPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DFA+ R IAD+ GA LM DMAHI+GLVAA +P Y VT+TTHK LRGPRG Sbjct: 174 YPRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAGVHPNPVPYAHFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ++ F +I+ A+FP +QGGP + IAA A+ L + Sbjct: 234 GMILCQE-------------------QFAKQIDKAIFPGIQGGPLMHVIAAKAVALGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 ++K Y ++V++NA+ LA+AL L++GGTDNHL+L DLR LTGK EKV + Sbjct: 275 QDDFKVYAKRVVENAKRLAAALQNEGFTLISGGTDNHLLLVDLRPQQLTGKTAEKVLDEV 334 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I++NK I Y G+RIGT A+TTRG ++ + IA I G VLK Sbjct: 335 GITVNKNTIPYDPESPFVTSGIRIGTAAVTTRGFGLEEMDEIA-------AIIGLVLKNV 387 Query: 1888 GKVQ 1899 G Q Sbjct: 388 GSEQ 391
>Q2JI36:GLYA_SYNJB Serine hydroxymethyltransferase - Synechococcus sp. (strain| JA-2-3B'a(2-13)) (Cyanobacteria bacterium Yellowstone B-Prime) Length = 427 Score = 318 bits (816), Expect = 5e-86 Identities = 193/429 (44%), Positives = 252/429 (58%), Gaps = 17/429 (3%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LAE DP V+ L+++E +RQ +E+IASENF AVL A GS LTNKY+EG PG RYYGG Sbjct: 4 LAETDPVVYRLIQQELNRQRDHLEMIASENFTSPAVLAAQGSVLTNKYAEGLPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + ID IE+L RA FG A NVQP+S AN AV+ LL P D IMG++ Sbjct: 64 CEFIDEIEQLAIDRAKQLFGAAHA----NVQPHSGAQANFAVFLALLQPGDTIMGMDLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S VSG +F + Y V+PQT ID+D++ D A+ PK++ICG S+ Sbjct: 120 GGHLTHG----SPVNVSGK--WFRVVHYGVHPQTERIDFDQVRDLALQHRPKLIICGYSA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DFA R IAD+ GA L+ D+AHI+GLVA +P CDVVT+TTHK LRGPRG Sbjct: 174 YPRAIDFAAFRTIADEVGAYLLADIAHIAGLVATGHHPNPVPLCDVVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D + K++ AVFP QGGP + IA A+ + Sbjct: 234 GLILTR------------------DPELGKKLDKAVFPGSQGGPLEHVIAGKAVAFGEAL 275 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFG------------L 1674 P + Y QV+ NAQALA +L RR RLV+GGTDNHL+L DLR+ + Sbjct: 276 QPSFAQYSAQVIANAQALAGSLQRRGIRLVSGGTDNHLMLLDLRSVSAVLEKTGAADPVM 335 Query: 1675 TGKNFEKVCELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGC----LEDDFEVIAD 1839 TGK +++ HI+ NK I + G+R+G+PA+TTRG E+ E+IAD Sbjct: 336 TGKRADRLMGKIHITANKNTIPFDPQPPFVASGLRLGSPALTTRGLGPVEFEEIGEIIAD 395 Query: 1840 FLIRATQIA 1866 L + + A Sbjct: 396 CLFQPEEPA 404
>Q8EM73:GLYA_OCEIH Serine hydroxymethyltransferase - Oceanobacillus iheyensis| Length = 411 Score = 318 bits (816), Expect = 5e-86 Identities = 183/451 (40%), Positives = 263/451 (58%), Gaps = 1/451 (0%) Frame = +1 Query: 637 EADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQ 816 +AD +V M+ E++RQ IELIASENFV +AV+DA+GS LTNKY+EG+PG RYYGG + Sbjct: 6 QADTEVFEAMQAEKNRQQDKIELIASENFVTKAVMDAMGSILTNKYAEGYPGKRYYGGCE 65 Query: 817 HIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGG 996 H+D +E L RA FG D A NVQP+S AN+AVY+ +L P D ++G+ GG Sbjct: 66 HVDVVENLARDRAKELFGADHA----NVQPHSGAQANMAVYSAVLEPGDTVLGMNLNHGG 121 Query: 997 HVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYP 1176 H++HG V+ + + + Y V+ +T +DYD + ++A + PK+++ G S+Y Sbjct: 122 HLTHG------SPVNFSGQLYNFVDYGVDKETEQLDYDAVLEKAKEVKPKLIVAGASAYS 175 Query: 1177 REWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGI 1356 R +FA+ R IAD A LM DMAHI+GLVA E +P + D VT+TTHK LRGPRGG+ Sbjct: 176 RSINFAKFREIADAVDAYLMVDMAHIAGLVATGEHENPVPHADFVTTTTHKTLRGPRGGM 235 Query: 1357 IFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATP 1536 I ++ +F K++ A+FP +QGGP + IAA A++ K+ + Sbjct: 236 ILCKE-------------------EFAKKVDKAIFPGIQGGPLMHVIAAKAVSFKEALSD 276 Query: 1537 EYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHI 1716 ++KAY +Q++ NA+ L AL + R+V+GGTDNHL+L D+ LTGK EK + I Sbjct: 277 DFKAYSKQIVANAKLLGEALNKEGIRIVSGGTDNHLLLLDVTPLQLTGKVAEKALDDIGI 336 Query: 1717 SINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQHGK 1893 + NK I D S G+RIGT A+TTRG E++ + IA I LK H Sbjct: 337 TTNKNTIPFDQESPFVTSGIRIGTAAVTTRGFGEEEMKEIA-------SIISLTLKHH-- 387 Query: 1894 VQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 E+ + E +V+A +F + Sbjct: 388 ---------EDEAKLKEAAQRVQALTEKFTL 409
>Q47XG4:GLYA3_COLP3 Serine hydroxymethyltransferase 3 - Colwellia psychrerythraea (strain| 34H / ATCC BAA-681) (Vibrio psychroerythus) Length = 431 Score = 318 bits (816), Expect = 5e-86 Identities = 183/406 (45%), Positives = 247/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L+ D V ++ E RQ + IELIASEN V +AV++A G+ LTNKY+EG+PG RYYGG Sbjct: 18 LSSTDGAVQVAIDLEEARQNQQIELIASENIVSKAVMEAQGTVLTNKYAEGYPGRRYYGG 77 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E L RA F D VNVQP+S AN AV L+ P D I+G+ + Sbjct: 78 CEHVDLVETLAIDRAKLIFKAD----FVNVQPHSGAQANGAVMLALVKPGDTILGMSLDA 133 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG K + + +F ++ Y V IDYD++ A++ PK++I GGS+ Sbjct: 134 GGHLTHG------AKPAQSGKWFNAIHYGVRKDDMRIDYDQVLALAIEHQPKMIIAGGSA 187 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 PR+ DFA+ R IAD+ GA+LM DMAHI+GLVAA ++P + DVVT+TTHK LRGPRG Sbjct: 188 IPRQIDFAKFREIADQVGAILMVDMAHIAGLVAAGAHQNPLPFADVVTTTTHKTLRGPRG 247 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I N+ D KIN AVFP LQGGP + IAA A+ L +V Sbjct: 248 GLIL------------------TNNPDVAKKINSAVFPGLQGGPLMHVIAAKAVALGEVL 289 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P + AYI+QV+ NA+ LAS L +R C +VT GTD HL+L DLR GL G E+ E Sbjct: 290 EPSFGAYIKQVLSNARVLASTLQQRGCDIVTDGTDTHLMLVDLRPKGLKGNTTEESLERA 349 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + + G+R+GTPA T+RG D+FE+I ++ Sbjct: 350 GITCNKNGIPFDSEKPMVTSGIRLGTPAGTSRGFGNDEFELIGQWI 395
>Q2LQM6:GLYA_SYNAS Serine hydroxymethyltransferase - Syntrophus aciditrophicus (strain| SB) Length = 417 Score = 318 bits (815), Expect = 6e-86 Identities = 178/403 (44%), Positives = 244/403 (60%), Gaps = 1/403 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + DP++ + E RQ +ELIASENFV AVL+A G +TNKY+EG+PG RYYGG Sbjct: 4 LMKTDPEIAEAIRLETRRQAGKLELIASENFVSEAVLEAQGCIMTNKYAEGYPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D E L +R FG D VNVQP+S T AN+AVY L D I+G+ Sbjct: 64 CEYVDIAENLAIERCKALFGADY----VNVQPHSGTQANMAVYFSALSVGDTILGMNLAH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH+SHG S SG F+ + Y V+ +T IDY+++ED A+ P++++ G S+ Sbjct: 120 GGHLSHG----SPANFSGK--FYNVVPYGVDRETETIDYNQVEDLALQHKPRMIVVGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF + R IADK GA++M D+AHI+GLVA SP C+ VTSTTHK LRGPRG Sbjct: 174 YPRTIDFEKFRAIADKVGALVMADIAHIAGLVATGLHPSPVPVCEYVTSTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G++ + ++ ++ VFP +QGGP + IAA A+ K+ Sbjct: 234 GLVMCQA-------------------SYQKTLSSRVFPGVQGGPLMHIIAAKAVAFKEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 T E+K Y Q++KNAQALA L+ R RLV+GGTDNHL+L DL GLTGK ++ + Sbjct: 275 TDEFKDYQSQIVKNAQALAKELIGRGYRLVSGGTDNHLLLMDLTDKGLTGKEAQESLDSA 334 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIA 1836 I++NK I + G + G+RIGTPA+T+RG E++ IA Sbjct: 335 GITVNKNGIPFDTRGPMVTSGIRIGTPALTSRGMKEEEMRTIA 377
>Q98A81:GLYA2_RHILO Serine hydroxymethyltransferase 2 - Rhizobium loti (Mesorhizobium| loti) Length = 437 Score = 318 bits (815), Expect = 6e-86 Identities = 178/411 (43%), Positives = 254/411 (61%), Gaps = 1/411 (0%) Frame = +1 Query: 616 WGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGA 795 +G L + D VH L+ R+R ++ ++LIASENF AVL+A GS NKY+EG+PGA Sbjct: 7 YGRSSLVQVDCRVHELLLRQRRQERTMLKLIASENFASSAVLEATGSIFANKYAEGYPGA 66 Query: 796 RYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMG 975 RYY GN+ +D +E L +R FG + A NVQPYS + AN AVY LL P D++MG Sbjct: 67 RYYAGNEIVDELETLAIERLKALFGSEHA----NVQPYSGSPANQAVYRALLSPRDKVMG 122 Query: 976 LEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILI 1155 L P GGH++HG+ V+ + ++ + Y ++ +T IDYD+L + A PK++ Sbjct: 123 LPLPEGGHLTHGW------SVNFSGTDYQRVPYGLHDKTQQIDYDRLRETARRERPKLIW 176 Query: 1156 CGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNL 1335 GG+SYPR +D+A M IA + + L+ D+AHISGL+ A +P +CDVVTST+HK++ Sbjct: 177 VGGTSYPRVFDYAAMAEIALEANSYLVADIAHISGLIVAGAHPNPVVHCDVVTSTSHKSI 236 Query: 1336 RGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAIT 1515 RGPRGG I + + S S+ ++ +I+ AVFP LQGGPH N IAALA+ Sbjct: 237 RGPRGGFILSKNEDRYQALYHSTSK-----HNLAKRIDRAVFPQLQGGPHMNTIAALAVA 291 Query: 1516 LKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEK 1695 L++ ATP ++ Y Q++KNA+ALA ALL R LVTGGTDNH+++ DLR L+GK + + Sbjct: 292 LQEAATPSFRTYGHQIVKNAKALAEALLGRGYYLVTGGTDNHMLILDLRDRPLSGKAYAE 351 Query: 1696 VCELCHISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I N + GD G+R+G+PA+T+ G E + IA F+ Sbjct: 352 RLARAGIITNFDMVPGDPRDPTVTSGIRLGSPAVTSMGMREAEMVQIAAFI 402
>Q92QU6:GLYA1_RHIME Serine hydroxymethyltransferase 1 - Rhizobium meliloti (Sinorhizobium| meliloti) Length = 431 Score = 318 bits (815), Expect = 6e-86 Identities = 182/413 (44%), Positives = 246/413 (59%), Gaps = 1/413 (0%) Frame = +1 Query: 613 AWGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPG 792 A+ + LA++DP++ +E+E RQ IELIASEN V RAVL+A GS +TNKY+EG+PG Sbjct: 8 AFFTRSLADSDPEIFGAIEKELGRQRHEIELIASENIVSRAVLEAQGSIMTNKYAEGYPG 67 Query: 793 ARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIM 972 RYYGG Q++D E L +RA FG++ A NVQP S + N AV+ LL P D M Sbjct: 68 KRYYGGCQYVDIAEALAIERAKKLFGVNFA----NVQPNSGSQMNQAVFLALLQPGDTFM 123 Query: 973 GLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKIL 1152 GL+ SGGH++HG V+ + +F +SY V +D D++ +A + PK++ Sbjct: 124 GLDLNSGGHLTHG------SPVNMSGKWFNVVSYGVREDDHLLDMDEVARKAREQKPKLI 177 Query: 1153 ICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKN 1332 I GG++Y R WD+ R R IAD+ GA LM DMAHI+GLVA + SPF +C V T+TTHK+ Sbjct: 178 IAGGTAYSRIWDWKRFREIADEVGAWLMVDMAHIAGLVAGGQHPSPFPHCHVATTTTHKS 237 Query: 1333 LRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAI 1512 LRGPRGG+I ND + KIN AVFP LQGGP + IAA A+ Sbjct: 238 LRGPRGGMIL------------------TNDEEIAKKINSAVFPGLQGGPLMHVIAAKAV 279 Query: 1513 TLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFE 1692 L + P +K Y QV+KNA+ LA L +V+GGTDNHL+L DLR TGK E Sbjct: 280 ALGEALQPSFKDYAAQVVKNARTLAETLKANGLDIVSGGTDNHLMLVDLRKKNATGKRAE 339 Query: 1693 KVCELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 +++ NK I + GVR+G PA TTRG E +F+ + + ++ Sbjct: 340 AALGRAYVTCNKNGIPFDPEKPFVTSGVRLGAPAGTTRGFKEAEFKEVGELIV 392
>Q3IZN2:GLYA_RHOS4 Serine hydroxymethyltransferase - Rhodobacter sphaeroides (strain| ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) Length = 431 Score = 317 bits (813), Expect = 1e-85 Identities = 185/410 (45%), Positives = 241/410 (58%), Gaps = 2/410 (0%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 + L+ DP++ A + E RQ IELIASEN V RAV++A GS +TNKY+EG+ G RYY Sbjct: 13 ESLSSRDPELFASITGELGRQRDEIELIASENIVSRAVMEAQGSVMTNKYAEGYAGKRYY 72 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG ++D E L +RA FG C VNVQP S + AN V+ L+ P D I+G+E Sbjct: 73 GGCDYVDVAETLAIERAKQLFG----CAYVNVQPNSGSQANQGVFQALIKPGDTILGMEL 128 Query: 985 PSGGHVSHGYY-TPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 SGGH++HG SGK +F ++ Y V Q IDYD++ A + PK++I G Sbjct: 129 ASGGHLTHGAAPNQSGK-------WFNAIQYGVRQQDQLIDYDQVAALAREHKPKLIIAG 181 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 GS+ PR+ DFAR R IAD+ GA+LM DMAH +GLVA SPF + DV T+TTHK LRG Sbjct: 182 GSAIPRQIDFARFRAIADEVGALLMVDMAHFAGLVAGGAHPSPFPHADVATTTTHKTLRG 241 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I N + K+N A+FP +QGGP + IAA A+ Sbjct: 242 PRGGMIL------------------TNSEEIAKKVNSAIFPGIQGGPLMHVIAAKAVAFG 283 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+KAY QV+KNAQALA L++ +VTGGTD HL+L DLR G+ G EK Sbjct: 284 EALRPEFKAYAAQVVKNAQALADELMKGGLDIVTGGTDTHLMLVDLRPKGVKGNATEKAL 343 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 HI+ NK I + GVR+GTPA TTRG E +F I ++ Sbjct: 344 GRAHITCNKNGIPFDPEKPTVTSGVRLGTPAGTTRGFGEAEFREIGRLIV 393
>Q88R12:GLYA1_PSEPK Serine hydroxymethyltransferase 1 - Pseudomonas putida (strain| KT2440) Length = 417 Score = 317 bits (813), Expect = 1e-85 Identities = 178/389 (45%), Positives = 237/389 (60%), Gaps = 1/389 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + A M E RQ IELIASEN+ + V+ A GS LTNKY+EG+PG RYYGG +H+ Sbjct: 12 DDALLAAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG D A NVQP+S +SAN AVY LL D I+G+ GGH+ Sbjct: 72 DKVEALAIERAKQLFGADYA----NVQPHSGSSANGAVYLALLQAGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KVS + + ++ Y ++ TG IDYD++E A++ PK+++ G S+Y + Sbjct: 128 THG------AKVSSSGKLYNAVQYGIDTNTGLIDYDEVERLAVEHKPKMIVAGFSAYSKT 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF R R IADK GA+L DMAH++GLVAA +P + DVVT+TTHK LRGPRGG+I Sbjct: 182 LDFPRFRAIADKVGALLFVDMAHVAGLVAAGLYPNPIPFADVVTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 + + + E K+N AVFP QGGP + IAA A+ K+ P + Sbjct: 242 AKSNE-----------------EIEKKLNAAVFPGAQGGPLMHVIAAKAVCFKEALEPGF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 KAY QQV++NAQA+A + R +V+GGTDNHL L L GLTGK+ + HI++ Sbjct: 285 KAYQQQVIENAQAMAQVFIDRGYDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRG 1806 NK + D S G+RIGTPA+TTRG Sbjct: 345 NKNAVPNDPQSPFVTSGLRIGTPAVTTRG 373
>Q4K4P6:GLYA2_PSEF5 Serine hydroxymethyltransferase 2 - Pseudomonas fluorescens (strain| Pf-5 / ATCC BAA-477) Length = 417 Score = 317 bits (811), Expect = 2e-85 Identities = 177/389 (45%), Positives = 237/389 (60%), Gaps = 1/389 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + A + E RQ IELIASEN+ + V+ A GS LTNKY+EG+PG RYYGG +H+ Sbjct: 12 DDALLAAINAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG D A NVQP+S +SAN VY LL D I+G+ GGH+ Sbjct: 72 DKVEALAIERAKQLFGADYA----NVQPHSGSSANSEVYLALLQAGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KVS + + ++ Y ++ +TG IDYD++E A++ PK+++ G S+Y + Sbjct: 128 THG------AKVSSSGKLYNAVQYGIDTRTGLIDYDEVERLAVEHKPKMIVAGFSAYSKT 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF R R IADK GA+L DMAH++GLVAA +P Y DVVT+TTHK LRGPRGG+I Sbjct: 182 LDFPRFRQIADKVGALLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 + + + E K+N AVFP QGGP + IAA A+ K+ P + Sbjct: 242 AKANE-----------------EIEKKLNAAVFPGAQGGPLMHVIAAKAVCFKEALEPGF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 KAY QQV+ NAQA+A ++R +V+GGTDNHL L L GLTGK+ + HI++ Sbjct: 285 KAYQQQVIDNAQAMAGVFIKRGYDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRG 1806 NK + D S G+RIGTPA+TTRG Sbjct: 345 NKNAVPNDPQSPFVTSGLRIGTPAVTTRG 373
>Q2W4T2:GLYA_MAGMM Serine hydroxymethyltransferase - Magnetospirillum magneticum (strain| AMB-1 / ATCC 700264) Length = 427 Score = 316 bits (809), Expect = 3e-85 Identities = 185/413 (44%), Positives = 243/413 (58%), Gaps = 2/413 (0%) Frame = +1 Query: 613 AWGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPG 792 A+ PL+E DP+V A + +E RQ IELIASEN V RAVL+A GS +TNKY+EG+PG Sbjct: 8 AFFRTPLSERDPEVFAAITQELKRQQDQIELIASENIVSRAVLEAQGSVMTNKYAEGYPG 67 Query: 793 ARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIM 972 RYYGG + +D E L RA FG C NVQP S + AN V+ LL P D IM Sbjct: 68 KRYYGGCEFVDIAESLAISRACQIFG----CSYANVQPSSGSQANQGVFMALLQPGDTIM 123 Query: 973 GLEPPSGGHVSHGYY-TPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKI 1149 G+ +GGH++HG SGK +F+++ Y V Q ID+ ++E+ A PK+ Sbjct: 124 GMSLAAGGHLTHGAAPNQSGK-------WFKAVQYGVRQQDSQIDFAEVEELARTHRPKL 176 Query: 1150 LICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHK 1329 +I GGS+YPR DFAR R IAD+ GA M DMAH +GLVA +P + VVT+TTHK Sbjct: 177 IIAGGSAYPRTIDFARFRKIADEVGAFFMVDMAHFAGLVAGGVYPNPLPHAHVVTTTTHK 236 Query: 1330 NLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALA 1509 LRGPRGG+I ND D KIN A+FP +QGGP + IA A Sbjct: 237 TLRGPRGGMIL------------------SNDADIGKKINSAIFPGIQGGPLMHVIAGKA 278 Query: 1510 ITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNF 1689 + + PE+K Y +QV+ NA+ALA L+RR +V+GGTD+HL+L DLR LTGK Sbjct: 279 VAFGEALKPEFKLYAKQVVDNARALADTLVRRGLDIVSGGTDSHLMLVDLRPKKLTGKAA 338 Query: 1690 EKVCELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 E E ++ NK I + GVR+GTPA TTRG ++F+ + + + Sbjct: 339 EASLEHAGMTCNKNGIPFDPEKPTITSGVRLGTPAATTRGFGVEEFKKVGELI 391
>Q88UT5:GLYA_LACPL Serine hydroxymethyltransferase - Lactobacillus plantarum| Length = 412 Score = 316 bits (809), Expect = 3e-85 Identities = 175/410 (42%), Positives = 250/410 (60%), Gaps = 2/410 (0%) Frame = +1 Query: 637 EADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQ 816 E DP+V A + +E+ RQ IELIASEN V + V A GS LTNKYSEG+PG R+YGGN+ Sbjct: 5 EQDPEVWAAISKEQARQQHNIELIASENIVSKGVRAAQGSVLTNKYSEGYPGHRFYGGNE 64 Query: 817 HIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGG 996 +ID +E L +RA FG + A NVQP+S + AN A Y L+ P DR+MG+ +GG Sbjct: 65 YIDQVETLAIERAKKLFGAEYA----NVQPHSGSQANAAAYMALIQPGDRVMGMSLDAGG 120 Query: 997 HVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYP 1176 H++HG V+ + ++ Y ++P+T ++YD + +A DF PK+++ G S+Y Sbjct: 121 HLTHG------SSVNFSGKLYDFQGYGLDPETAELNYDAILAQAQDFQPKLIVAGASAYS 174 Query: 1177 REWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGI 1356 R DF + R IAD+ GA+LM DMAHI+GLVAA +P Y DVVT+TTHK LRGPRGG+ Sbjct: 175 RLIDFKKFREIADQVGALLMVDMAHIAGLVAAGLHPNPVPYADVVTTTTHKTLRGPRGGM 234 Query: 1357 IFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATP 1536 I ++ + KIN AVFP QGGP ++ IA AI L + P Sbjct: 235 ILAKE-------------------KYGKKINSAVFPGNQGGPLDHVIAGKAIALGEDLQP 275 Query: 1537 EYKAYIQQVMKNAQALASALLRRK-CRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCH 1713 E+K Y Q ++ NA+A+A R+++GGTDNHL+ D+ GL G+ + + + + Sbjct: 276 EFKVYAQHIIDNAKAMAKVFNDSDLVRVISGGTDNHLMTIDVTKSGLNGRQVQDLLDTVY 335 Query: 1714 ISINKTPIYGDN-GSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 I++NK I + G+ G+R+GTPA+TTRG E D +A+ +++A Q Sbjct: 336 ITVNKEAIPNETLGAFKTSGIRLGTPAITTRGFDEADATKVAELILQALQ 385
>Q9I138:GLYA2_PSEAE Serine hydroxymethyltransferase 2 - Pseudomonas aeruginosa| Length = 418 Score = 316 bits (809), Expect = 3e-85 Identities = 178/402 (44%), Positives = 242/402 (60%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D ++ A M+ E RQ IELIASEN+ + V+ A G LTNKY+EG+PG RYYGG +H+ Sbjct: 12 DDELLAAMDAEDRRQEDHIELIASENYASKRVMQAQGGGLTNKYAEGYPGKRYYGGCEHV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +ERL RA FG D A NVQP+S +SAN AVY LL D I+G+ GGH+ Sbjct: 72 DKVERLAIDRARQLFGADYA----NVQPHSGSSANAAVYLALLNAGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KVS + + ++ Y ++ TG IDYD++E A++ PK+++ G S+Y + Sbjct: 128 THG------AKVSSSGKLYNAVQYGLDTATGLIDYDEVERLAVEHKPKMIVAGFSAYSKT 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF R R IADK GA+L DMAH++GLVAA +P + DVVT+TTHK LRGPRGG+I Sbjct: 182 LDFPRFRAIADKVGALLFVDMAHVAGLVAAGLYPNPIPFADVVTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 R + + E K+N AVFP QGGP + IAA A+ K+ P + Sbjct: 242 ARANE-----------------EIEKKLNSAVFPGAQGGPLMHVIAAKAVCFKEALEPGF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y QV++NA+A+A + R +V+GGTDNHL+L L GLTGK + HI++ Sbjct: 285 KDYQAQVIRNAKAMAEVFIGRGYDVVSGGTDNHLMLISLVKQGLTGKAADAALGAAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + D S G+RIGTPA+TTRG E + +A ++ Sbjct: 345 NKNAVPNDPQSPFVTSGIRIGTPAVTTRGFREGECRELAGWI 386
>Q38WJ7:GLYA_LACSS Serine hydroxymethyltransferase - Lactobacillus sakei subsp. sakei| (strain 23K) Length = 415 Score = 315 bits (807), Expect = 5e-85 Identities = 180/412 (43%), Positives = 248/412 (60%), Gaps = 2/412 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DP ++ L+++E +RQ IELIASEN V AV +A GS LTNKY+EG+P R+YGG Sbjct: 2 LAKTDPVINDLIKQEENRQRHNIELIASENIVSGAVQEAQGSVLTNKYAEGYPNKRFYGG 61 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 ++ID IE L +RA FG D VNVQP+S + AN+AVY LL P D+I+G+ Sbjct: 62 CEYIDQIETLAIERAKELFGADH----VNVQPHSGSQANMAVYQALLEPGDKILGMNLTD 117 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S SG ++ SY V +DY L +A + HPK+++ G S+ Sbjct: 118 GGHLTHG----SPFNFSGQ--LYDFYSYGVADTNEQLDYASLAAKAQEVHPKMIVAGASA 171 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF R+R IAD+ GA LM DMAHI+GLVA SP Y DVVT+TTHK LRGPRG Sbjct: 172 YSRTIDFPRLREIADQVGAYLMIDMAHIAGLVATGVHPSPVPYADVVTTTTHKTLRGPRG 231 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++ I+ A+FP +QGGP + IAA A+ + Sbjct: 232 GMILCKA-------------------EYAKAIDSAIFPGIQGGPLEHVIAAKAVAFGEAL 272 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRK-CRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 PE+ AY +Q++ NAQA+A+ + R+V+GGTDNHL+L DL GL GK + + + Sbjct: 273 QPEFTAYTKQIVANAQAMAAVFDQSDLVRVVSGGTDNHLMLLDLTNSGLNGKELQNLLDS 332 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 HI++NK I + G+RIGTPA+T+RG E D E IA+ ++ + Sbjct: 333 VHITVNKNTIPFEKLSPFKTSGIRIGTPAITSRGFKEKDCEQIANLILEVIE 384
>P34895:GLYA_HYPME Serine hydroxymethyltransferase - Hyphomicrobium methylovorum| Length = 434 Score = 315 bits (807), Expect = 5e-85 Identities = 178/402 (44%), Positives = 240/402 (59%), Gaps = 1/402 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 ++E DPD+ + +++E RQ IELIASEN V +AVLDA GS LTNKY+EG+PG RYYGG Sbjct: 20 VSETDPDIFSAIQKEFGRQQHEIELIASENIVSQAVLDAAGSVLTNKYAEGYPGKRYYGG 79 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 Q++D +E + RA F C NVQP S + AN V+ L P D I+GL + Sbjct: 80 CQYVDIVEDIAIDRAKKLFN----CEFANVQPNSGSQANQGVFNALAQPGDTILGLSLAA 135 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F+++ Y V P + ID D++ A + P+I+I GGS+ Sbjct: 136 GGHLTHG------APVNQSGKWFKAVHYMVKPDSHLIDMDEVRKLAQEHKPRIIIAGGSA 189 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR+ DFA R IAD+ GA+ + DMAH +GLVAA SPF + VVT+TTHK LRGPRG Sbjct: 190 YPRKIDFAAFRAIADEVGAIFLVDMAHFAGLVAAGLIPSPFPHAHVVTTTTHKTLRGPRG 249 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ND D KIN A+FP +QGGP + IA A+ + Sbjct: 250 GMIL------------------TNDADIAKKINSAIFPGIQGGPLMHVIAGKAVAFGEAL 291 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P++K YI+QVM NA+AL L++ LV+GGTD HLVL DLR LTG EK Sbjct: 292 RPDFKVYIKQVMDNARALGEVLVQNGFALVSGGTDTHLVLVDLRPKKLTGTKAEKALGRA 351 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVI 1833 +I+ NK I + + G+R+G+PA TTRG +F+ I Sbjct: 352 NITCNKNGIPFDPEKPMVTSGIRLGSPAGTTRGFGVAEFQEI 393
>Q8KC36:GLYA_CHLTE Serine hydroxymethyltransferase - Chlorobium tepidum| Length = 440 Score = 314 bits (805), Expect = 9e-85 Identities = 180/422 (42%), Positives = 246/422 (58%), Gaps = 7/422 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L DP+V + E RQ +ELIASENF +AV++A GS +TNKY+EG+PG RY Sbjct: 3 NDILKRLDPEVFEAIANETKRQTETLELIASENFTSKAVMEACGSVMTNKYAEGYPGKRY 62 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + +D E L RA FG C VNVQP+S +SAN+AV +L P D IMGL+ Sbjct: 63 YGGCEFVDVAENLARDRAKKLFG----CEYVNVQPHSGSSANMAVLFAVLKPGDAIMGLD 118 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG KV+ + FF++ SY V+ +TG ID +K+E+ A PK++I G Sbjct: 119 LSHGGHLTHG------SKVNFSGQFFDAHSYGVDKETGIIDMNKVEEMARRVKPKLIITG 172 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y + +DF R +ADK GA+LM D+AH +GLVAA +P +C VT+TTHK LRG Sbjct: 173 ASAYSQGFDFKAFREVADKVGALLMADIAHPAGLVAAGLSANPMPHCHFVTTTTHKTLRG 232 Query: 1342 PRGGIIFFRK------GKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAA 1503 PRGG+I K G + + GS + + I+ V P +QGGP + IA Sbjct: 233 PRGGMIMMGKDFENPLGLTINTKNGSRVK------MMSEVIDAEVMPGIQGGPLMHIIAG 286 Query: 1504 LAITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGK 1683 A+ + PE+KAY QQ+ NA A+A+ L +V+GGT NHL+L DLR + GK Sbjct: 287 KAVAFGEALQPEFKAYAQQIKDNAAAMAAKFLAAGYHIVSGGTKNHLMLLDLRNKNVNGK 346 Query: 1684 NFEKVCELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 E + I++NK + + D G+RIGTPAMTTRG + E I +F+ R Sbjct: 347 VAENLLHEAGITVNKNMVPFDDKSPFVTSGIRIGTPAMTTRGMKVAEAEKIVEFIDRVIS 406 Query: 1861 IA 1866 A Sbjct: 407 AA 408
>Q31CS4:GLYA_PROM9 Serine hydroxymethyltransferase - Prochlorococcus marinus (strain MIT| 9312) Length = 423 Score = 314 bits (804), Expect = 1e-84 Identities = 180/413 (43%), Positives = 249/413 (60%), Gaps = 5/413 (1%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 Q L ++DP + + E++RQ +ELIASENF AV+ A GS LTNKY+EG P RYY Sbjct: 5 QNLKKSDPVISNFINSEKNRQETHLELIASENFASIAVMQAQGSVLTNKYAEGLPQKRYY 64 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG + +D IE L QRA F A W NVQP+S AN AV+ LL P D IMG++ Sbjct: 65 GGCEFVDEIEELAIQRAKKLFN---ANWA-NVQPHSGAQANAAVFLSLLQPGDTIMGMDL 120 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 GGH++HG V+ + +F ++ Y VN +T +++D++ + A++ PK++ICG Sbjct: 121 SHGGHLTHG------SPVNMSGKWFNAVHYGVNKETSELNFDEIREIALETKPKLIICGY 174 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S+YPR DF R IAD+ GA LM D+AHI+GLVA+K +P YCDVVT+TTHK LRGP Sbjct: 175 SAYPRTIDFESFRNIADEVGAFLMADIAHIAGLVASKLHPNPLPYCDVVTTTTHKTLRGP 234 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 RGG+I + G +F K + +VFP QGGP + IAA A+ + Sbjct: 235 RGGLILCKDG------------------EFGKKFDKSVFPGTQGGPLEHIIAAKAVAFGE 276 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 P++ Y QQV+KNA+ LAS L+ R +V+GGTDNH+VL DLR+ +TGK + + Sbjct: 277 ALQPDFVNYSQQVIKNAKVLASTLISRGIDIVSGGTDNHIVLLDLRSINMTGKIADLLVS 336 Query: 1705 LCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDF----EVIADFLI 1848 +I+ NK + + G+R+GT A+TTRG E F E+IAD L+ Sbjct: 337 AVNITANKNTVPFDPESPFVTSGLRLGTAALTTRGFNETAFAEVGEIIADRLL 389
>Q7VFL1:GLYA_HELHP Serine hydroxymethyltransferase - Helicobacter hepaticus| Length = 416 Score = 314 bits (804), Expect = 1e-84 Identities = 188/434 (43%), Positives = 255/434 (58%), Gaps = 6/434 (1%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + E D +V L+E+E +RQ +E+IASENF +V++A+GS LTNKY+EG+P RYYGG Sbjct: 5 IKEQDFEVFELIEKELERQNEHLEMIASENFTFPSVMEAMGSILTNKYAEGYPFKRYYGG 64 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D IE + +RA FG + VNVQP+S + AN AVY +L P D+I+G++ Sbjct: 65 CEFVDKIEEIAIERAKKLFGAN----FVNVQPHSGSQANAAVYAAILKPYDKILGMDLSH 120 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG KVS + ++S Y V G IDYDKL +A P +L+CG S+ Sbjct: 121 GGHLTHG------AKVSTSGQLYQSFFYGVE-LNGRIDYDKLALQAQVVKPNVLVCGFSA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y RE DF R+R IAD GA LM D+AH++GLV A E +PF +C +VT+TTHK LRGPRG Sbjct: 174 YTRELDFKRLREIADSVGAYLMGDIAHVAGLVVAGEYPNPFPHCHIVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G I ND + KIN AVFP +QGGP + IA A+ K+ Sbjct: 234 GAIL------------------TNDEELYAKINKAVFPGIQGGPLMHIIAGKAVGFKENL 275 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y +QV N QALA L++R LV+GG+DNHL+L +GK+ + Sbjct: 276 KPEWKIYAKQVKSNIQALAEVLIKRNYELVSGGSDNHLILMSFLNKDFSGKDADLALGNA 335 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDF----EVIADFLIRATQIAGSV 1875 I++NK I G+ G+RIG+PA+T RG E +F E IAD L I + Sbjct: 336 GITVNKNTIPGEIRSPFITSGIRIGSPALTARGMKEKEFEWIGEKIADIL---DDINNTN 392 Query: 1876 LKQHGKVQ-KEFLR 1914 L++H K Q K F R Sbjct: 393 LQEHIKAQVKNFSR 406
>Q8YMW8:GLYA_ANASP Serine hydroxymethyltransferase - Anabaena sp. (strain PCC 7120)| Length = 427 Score = 314 bits (804), Expect = 1e-84 Identities = 183/411 (44%), Positives = 247/411 (60%), Gaps = 5/411 (1%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L +DP + L+ +E RQ +ELIASENF AVL A GS LTNKY+EG PG RYYGG Sbjct: 9 LTNSDPAIAGLINQELQRQRDHLELIASENFTSAAVLAAQGSVLTNKYAEGLPGKRYYGG 68 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + ID IE++ RA FG D A NVQP+S AN AV+ LL P D+IMG++ Sbjct: 69 CEFIDKIEQIAIDRAKQLFGADHA----NVQPHSGAQANFAVFLTLLKPGDKIMGMDLSH 124 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S VSG +F+ Y V+ QT +DYD++ + A+ PK+LICG S+ Sbjct: 125 GGHLTHG----SPVNVSGK--WFQVCHYGVSQQTEQLDYDQIRELALRERPKLLICGYSA 178 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF + R IAD+ GA L+ D+AHI+GLVA +P YCDVVT+TTHK LRGPRG Sbjct: 179 YPRIIDFEKFRSIADEVGAYLLADIAHIAGLVATGLHPNPLPYCDVVTTTTHKTLRGPRG 238 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D + K++ +VFP QGGP + IA A+ + Sbjct: 239 GLILTR------------------DAELGKKLDKSVFPGTQGGPLEHVIAGKAVAFGEAL 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE++ Y QV+ NA+ LA+ L R +LV+ GTDNHL+L DLR+ +TGK +++ Sbjct: 281 KPEFQGYSAQVIDNARTLANQLQTRGLKLVSDGTDNHLMLVDLRSVNMTGKRADQLVSEV 340 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDF----EVIADFLI 1848 +I+ NK + + G+R+G+PAMTTRG E +F +IAD L+ Sbjct: 341 NITANKNTVPFDPQSPFVTSGLRLGSPAMTTRGMGEAEFTEIGNIIADRLL 391
>Q4ZM83:GLYA2_PSEU2 Serine hydroxymethyltransferase 2 - Pseudomonas syringae pv. syringae| (strain B728a) Length = 417 Score = 314 bits (804), Expect = 1e-84 Identities = 178/389 (45%), Positives = 234/389 (60%), Gaps = 1/389 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + + M E RQ IELIASEN+ + V+ A GS LTNKY+EG+PG RYYGG +H+ Sbjct: 12 DDALLSAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E+L +RA FG D A NVQP+S + AN AVY LL D ++G+ GGH+ Sbjct: 72 DKVEQLAIERARQLFGADYA----NVQPHSGSQANAAVYLALLQAGDTVLGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KVS + + ++ Y ++ TG IDYD++E A++ PK++I G S+Y + Sbjct: 128 THG------AKVSFSGKLYNAVQYGIDTATGLIDYDEVERIAVECQPKMIIAGFSAYSKT 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF R R IADK GA L DMAH++GLVAA +P Y DVVT+TTHK LRGPRGG+I Sbjct: 182 LDFPRFRAIADKVGAYLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 R + + K K N AVFP QGGP + IAA A+ K+ P + Sbjct: 242 ARANEELEK-----------------KFNSAVFPGGQGGPLMHVIAAKAVCFKEAMEPGF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 KAY QQV+ NAQA+A + R +V+GGTDNHL L L GLTGK+ + HI++ Sbjct: 285 KAYQQQVIDNAQAMAQVFIDRGFDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRG 1806 NK + D S G+RIGTPA+TTRG Sbjct: 345 NKNSVPNDPQSPFVTSGLRIGTPAVTTRG 373
>Q7MXW0:GLYA_PORGI Serine hydroxymethyltransferase - Porphyromonas gingivalis| (Bacteroides gingivalis) Length = 426 Score = 313 bits (803), Expect = 2e-84 Identities = 177/406 (43%), Positives = 241/406 (59%), Gaps = 3/406 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + L+E+E RQ++GIELIASENFV V+ A+GS +TNKY+EG+PG RYYGG + + Sbjct: 4 DSVIFDLIEKEHQRQLKGIELIASENFVSEQVMQAMGSCMTNKYAEGYPGKRYYGGCEVV 63 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E++ R +G + A NVQP+S AN+AV L D MGL GGH+ Sbjct: 64 DQSEQIAIDRIKQLYGAEWA----NVQPHSGAQANMAVLLACLEAGDTFMGLNLEHGGHL 119 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 SHG V+ + I + + Y ++ +TG +DYD +E A++ PK++I GGS+Y RE Sbjct: 120 SHG------SLVNSSGILYRPIGYNLSEETGMVDYDHMEKMAIEHKPKLIIGGGSAYSRE 173 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 WD+ RMR IADK GA+LM DMAH +GL+AA +P Y +VTSTTHK LRGPRGGII Sbjct: 174 WDYKRMREIADKVGALLMIDMAHPAGLIAAGLLENPVKYAHIVTSTTHKTLRGPRGGIIL 233 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 GK+ G + E ++ AVFP +QGGP + IAA A+ + P + Sbjct: 234 M--GKDFDNPWGKKTPKGEIK-KMSALLDSAVFPGVQGGPLEHVIAAKAVAFGEALDPSF 290 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTF--GLTGKNFEKVCELCHI 1716 K Y QV KNA LA A + + ++++GGTDNH +L DLR LTGK EK I Sbjct: 291 KEYQTQVKKNAAVLAQAFMDKGYKVISGGTDNHSMLIDLRPKFPELTGKVAEKALVAADI 350 Query: 1717 SINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIR 1851 ++NK + + + G R+GTPA+TTRG ED I + + R Sbjct: 351 TVNKNMVPFDSRSAFQTSGFRVGTPAITTRGVKEDKMGYIVELIDR 396
>Q9A8J6:GLYA_CAUCR Serine hydroxymethyltransferase - Caulobacter crescentus (Caulobacter| vibrioides) Length = 429 Score = 313 bits (803), Expect = 2e-84 Identities = 180/407 (44%), Positives = 244/407 (59%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA AD D+ + RE RQ IELIASEN V +AVL+A GS LTNKY+EG+PG RYYGG Sbjct: 15 LATADRDIFDRIGRELGRQQNQIELIASENIVSKAVLEAQGSILTNKYAEGYPGKRYYGG 74 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D IE + +RA FG A NVQP+S + AN AV+ LL P D +G++ + Sbjct: 75 CEYVDEIETIAIERAKALFGAGFA----NVQPHSGSQANQAVFMALLQPGDTFLGMDLAA 130 Query: 991 GGHVSHGY-YTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 GGH++HG SGK +F+ +SY V Q IDYD + + A PK++I GGS Sbjct: 131 GGHLTHGSPANQSGK-------WFKPISYSVRQQDQLIDYDGVAEVAQREKPKLIIAGGS 183 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 +Y RE DFA+ R IAD GA LM DMAH +GL+A +P + +VT+TTHK LRGPR Sbjct: 184 AYSREIDFAKFREIADSIGAYLMVDMAHYAGLIAGGAYANPIPHAHIVTTTTHKTLRGPR 243 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 GG++ ND K+N AVFP LQGGP + IAA A+ + Sbjct: 244 GGLVL------------------TNDEAIIKKVNSAVFPGLQGGPLEHVIAAKAVAFGEA 285 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 P +K Y +QV+ NA+ALA ALL+ +V+GGTD+HL+L DLR G+TG++ E E Sbjct: 286 LQPSFKDYARQVVANARALAEALLKSGVNIVSGGTDSHLMLVDLRPKGVTGRDAEHSLER 345 Query: 1708 CHISINKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +++ NK + D + G+R+GTPA TTRG E +F + + + Sbjct: 346 AYMTCNKNGVPFDTAPFTITSGIRLGTPAGTTRGFKEAEFTRVGELI 392
>P39148:GLYA_BACSU Serine hydroxymethyltransferase - Bacillus subtilis| Length = 415 Score = 313 bits (803), Expect = 2e-84 Identities = 176/409 (43%), Positives = 244/409 (59%), Gaps = 1/409 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L D V ++ ER+RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 LPAQDEQVFNAIKNERERQQTKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E + RA FG + VNVQP+S AN+AVY +L D ++G+ Sbjct: 64 CEHVDVVEDIARDRAKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + + Y V+ +T YIDYD + ++A+ PK+++ G S+ Sbjct: 120 GGHLTHG------SPVNFSGVQYNFVEYGVDKETQYIDYDDVREKALAHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF + R IAD+ GA M DMAHI+GLVAA +P Y D VT+TTHK LRGPRG Sbjct: 174 YPRTIDFKKFREIADEVGAYFMVDMAHIAGLVAAGLHPNPVPYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R+ +F KI+ ++FP +QGGP + IAA A++ +V Sbjct: 234 GMILCRE-------------------EFGKKIDKSIFPGIQGGPLMHVIAAKAVSFGEVL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 ++K Y Q V+ NA+ LA AL + +LV+GGTDNHL+L DLR+ GLTGK E V + Sbjct: 275 QDDFKTYAQNVISNAKRLAEALTKEGIQLVSGGTDNHLILVDLRSLGLTGKVAEHVLDEI 334 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 I+ NK I Y G+R+GT A+T+RG D E + + A Sbjct: 335 GITSNKNAIPYDPEKPFVTSGIRLGTAAVTSRGFDGDALEEVGAIIALA 383
>Q73GC3:GLYA_WOLPM Serine hydroxymethyltransferase - Wolbachia pipientis wMel| Length = 425 Score = 313 bits (802), Expect = 2e-84 Identities = 179/411 (43%), Positives = 246/411 (59%), Gaps = 1/411 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L D +V+ +E+E RQ ++LIASENF +AV++A GS LTNKY+EG+PG RYY G Sbjct: 15 LKSFDNEVYQSIEKELQRQKSQLQLIASENFASKAVMEAQGSFLTNKYAEGYPGKRYYCG 74 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D IE L +R FG+ A NVQP+S + AN AV+ LL P D I+GL Sbjct: 75 CEHVDKIESLAIERLCKLFGVKFA----NVQPHSGSQANQAVFASLLTPGDTILGLSLSC 130 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG + +SG +F+S+ Y VN T ++ D++E A++ PK++I G S+ Sbjct: 131 GGHLTHG----AAPSLSGK--WFKSIQYTVNKDTYLLNMDEIEKLALEHKPKLIIAGASA 184 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR+ DF R R IADK GA L+ D+AH +GL+AA E SP +Y V+TSTTHK LRGPRG Sbjct: 185 YPRKMDFKRFREIADKVGAYLLADIAHYAGLIAAGEYPSPAEYAHVMTSTTHKTLRGPRG 244 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 GI+ ND KI AVFP LQGGP + IAA A+ K+ Sbjct: 245 GIVM------------------TNDEALHKKIQSAVFPGLQGGPLMHVIAAKAVAFKEAL 286 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y ++V++NA+ LA L + ++TGGTD+H+VL DLR+ LTGK+ E Sbjct: 287 APEFKTYSKKVVENAKVLAQELQKHGLDIITGGTDSHIVLVDLRSQKLTGKDVVDSLERA 346 Query: 1711 HISINKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 I+ NK + D + G+R GT A TTRG ++F+ IA + Q Sbjct: 347 GITCNKNSVPFDTAKPTITSGLRFGTAAETTRGLEAENFKEIAGLINEVIQ 397
>O66776:GLYA_AQUAE Serine hydroxymethyltransferase - Aquifex aeolicus| Length = 428 Score = 313 bits (802), Expect = 2e-84 Identities = 172/406 (42%), Positives = 246/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + DP+V + +E +RQ +E+IASENF AV++A GS LTNKY+EG PG RYYGG Sbjct: 4 LLKTDPEVFDAVVKEYERQFYNLEMIASENFTSLAVMEATGSVLTNKYAEGLPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E L +RA FG + A NVQP+S + AN+AVY +L P D IMG++ Sbjct: 64 CEYVDVVENLAIERAKKLFGAEHA----NVQPHSGSQANMAVYFAVLNPGDTIMGMDLAH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG KV+ + + + Y VNP+T IDYD+L A + PK+++ G S+ Sbjct: 120 GGHLTHG------AKVNFSGKLYNVIHYGVNPETELIDYDQLYKLAKEHKPKLIVGGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR +D+A+MR IAD+ GA+ M DMAH +GL+A +P Y VTSTTHK LRGPR Sbjct: 174 YPRVFDWAKMREIADEVGALFMVDMAHYAGLIAGGVYPNPVPYAQFVTSTTHKTLRGPRS 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G I K ++ ++ +VFP +QGGP + IAA A+ K+ Sbjct: 234 GFILTTK-------------------EYAKAVDKSVFPGIQGGPLMHVIAAKAVAFKEAM 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 + E+K Y +QV++NA+ LA L + ++VTGGTD+H+VL DLR + GK+ EK E Sbjct: 275 SEEFKEYAKQVVENARVLAEELKKYGFKIVTGGTDSHIVLVDLRNKNIIGKDAEKALEKA 334 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK + + G+RIGT A+TTRG ED+ IA ++ Sbjct: 335 GITVNKNAVPFDPLPPTKTSGIRIGTAALTTRGMKEDEMRKIAGWI 380
>O85718:GLYA_ACIRA Serine hydroxymethyltransferase - Acinetobacter radioresistens| Length = 417 Score = 313 bits (802), Expect = 2e-84 Identities = 178/411 (43%), Positives = 247/411 (60%), Gaps = 1/411 (0%) Frame = +1 Query: 616 WGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGA 795 + N +AE DP++ + E RQ IELIASEN+ AV++A GS LTNKY+EG+PG Sbjct: 2 FANISIAEFDPELAQAITNEDARQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGK 61 Query: 796 RYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMG 975 RYYGG +++D IE+L RA FG D A NVQP++ + AN AVY LL P D ++G Sbjct: 62 RYYGGCEYVDIIEQLAIDRAKELFGADYA----NVQPHAGSQANSAVYLALLNPGDTVLG 117 Query: 976 LEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILI 1155 + GGH++HG KVS + + ++ Y +NP+TG IDY+++E A++ P++++ Sbjct: 118 MSLAHGGHLTHG------AKVSFSGKTYNAIQYGLNPETGEIDYEEVERLALEHKPRMIV 171 Query: 1156 CGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNL 1335 G S+Y + D+ R R IADK GA L DMAH++GLVAA +P DV T+TTHK L Sbjct: 172 AGFSAYSQIVDWQRFRDIADKIGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTL 231 Query: 1336 RGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAIT 1515 RGPR G+I + + + E K+ AVFP QGGP + +AA AI Sbjct: 232 RGPRSGLILAKANE-----------------EIEKKLQSAVFPGNQGGPLVHAVAAKAIC 274 Query: 1516 LKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEK 1695 K+ PEYKAY QQV+KNAQA+A L+ R +V+GGT NHL L L +TGK+ + Sbjct: 275 FKEAMAPEYKAYQQQVVKNAQAMAEVLIERGYDVVSGGTKNHLFLLSLIKQDITGKDADA 334 Query: 1696 VCELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK + D S G+RIGTPA+TTRG E + +A ++ Sbjct: 335 WLGAAHITVNKNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRDLASWI 385
>Q6FA66:GLYA_ACIAD Serine hydroxymethyltransferase - Acinetobacter sp. (strain ADP1)| Length = 417 Score = 313 bits (801), Expect = 3e-84 Identities = 180/411 (43%), Positives = 247/411 (60%), Gaps = 1/411 (0%) Frame = +1 Query: 616 WGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGA 795 + N L+E DP++ +E E RQ IELIASEN+ AV++A GS LTNKY+EG+PG Sbjct: 2 FANISLSEFDPELAKSIEAEDARQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGK 61 Query: 796 RYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMG 975 RYYGG +++D IE+L RA FG D A NVQP++ + AN AVY LL D ++G Sbjct: 62 RYYGGCEYVDVIEQLAIDRAKALFGADYA----NVQPHAGSQANSAVYLALLNAGDTVLG 117 Query: 976 LEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILI 1155 + GGH++HG KV+ + + ++ Y +NP+TG IDYD++E A++ P++++ Sbjct: 118 MSLAHGGHLTHG------AKVNFSGKTYNAVQYGLNPETGEIDYDEVERLAIEHKPRMIV 171 Query: 1156 CGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNL 1335 G S+Y R D+ R R IADK GA L DMAH++GLVAA SP DV T+TTHK L Sbjct: 172 AGFSAYSRIVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPSPVQIADVTTTTTHKTL 231 Query: 1336 RGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAIT 1515 RGPR G+I + + + E K+ AVFP QGGP + IAA A+ Sbjct: 232 RGPRSGLILAKANE-----------------EIEKKLQSAVFPGNQGGPLVHAIAAKAVC 274 Query: 1516 LKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEK 1695 K+ PEYKAY QQV+KNAQA+A L+ R +V+GGTDNHL L L +TGK + Sbjct: 275 FKEAMAPEYKAYQQQVVKNAQAMAEVLIARGYDIVSGGTDNHLFLLSLIKQDVTGKEADA 334 Query: 1696 VCELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+RIGTPA+TTRG E + +A ++ Sbjct: 335 WLGNANITVNKNAVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRDLASWI 385
>Q9KMP4:GLYA2_VIBCH Serine hydroxymethyltransferase 2 - Vibrio cholerae| Length = 435 Score = 313 bits (801), Expect = 3e-84 Identities = 189/456 (41%), Positives = 259/456 (56%), Gaps = 3/456 (0%) Frame = +1 Query: 628 PLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYG 807 PLA + V A ++ E RQ IELIASEN V +AV+ A G+ LTNKY+EG+PG RYYG Sbjct: 21 PLAATNDAVFAAIQAEYTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYG 80 Query: 808 GNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPP 987 G +H+D++E++ +RA F C NVQP+S AN AV LL P D IMG+ Sbjct: 81 GCEHVDSVEQIAIERAKMLF----QCQYANVQPHSGAQANGAVMLALLQPGDTIMGMSLD 136 Query: 988 SGGHVSHGYYTP-SGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 +GGH++HG SGK +F ++ Y V+ QT I+YD + A++ PK++I GG Sbjct: 137 AGGHLTHGARPALSGK-------WFNAVQYGVDRQTLEINYDSVRALALEHKPKMIIAGG 189 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S+ PR DFA+ R I D+ GA+LM DMAHI+GLVA SP + VVT+TTHK LRGP Sbjct: 190 SAIPRTIDFAQFRSIVDEVGALLMVDMAHIAGLVATGAHPSPLPHAHVVTTTTHKTLRGP 249 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 RGG+I N + KIN AVFP LQGGP + IAA A+ + Sbjct: 250 RGGMIL------------------TNSEEIHKKINSAVFPGLQGGPLMHVIAAKAVAFGE 291 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 PE++ YI V+ NA+ LA L R C +VTGGTD HL+L DLR GL G E+ E Sbjct: 292 ALGPEFRTYIDSVIDNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNQVEQALE 351 Query: 1705 LCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLK 1881 I+ NK I + + + G+R+GTPA T+RG ++F++I +++ Sbjct: 352 RAGITCNKNGIPFDEEKPMITSGIRLGTPAGTSRGFGREEFKLIGEWI------------ 399 Query: 1882 QHGKVQKEFLRGLENNKDI-IELGNQVEAFASQFAM 1986 G V + E N D+ ++ QV+A +F + Sbjct: 400 --GDVLDGLVASPEGNPDVEQQVRKQVKALCQRFPL 433
>Q8Z2Z9:GLYA2_SALTI Serine hydroxymethyltransferase 2 - Salmonella typhi| Length = 419 Score = 313 bits (801), Expect = 3e-84 Identities = 187/416 (44%), Positives = 242/416 (58%), Gaps = 1/416 (0%) Frame = +1 Query: 601 RAVRAWGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSE 780 R R N PL + L+ +E+ RQ +ELIASENF AVL A GS LTNKY+E Sbjct: 4 RGNRMINNDPLFD-------LLNKEQQRQQHSLELIASENFASPAVLAAQGSVLTNKYAE 56 Query: 781 GHPGARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPN 960 G+ RYYGG + ID +E L RA FG VNVQP+S + AN AVY LL P Sbjct: 57 GYYQHRYYGGCKFIDEVEMLAITRAQQLFGARY----VNVQPHSGSQANQAVYLALLKPG 112 Query: 961 DRIMGLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFH 1140 D+I+G+ GGH++HG V+ + +F + Y V+ +G ID D++E A Sbjct: 113 DKILGMSLQCGGHLTHG------SPVNQSGKWFNAFHYGVDAHSGLIDMDEVETIAKRER 166 Query: 1141 PKILICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTST 1320 P+++I GGS+YPR +DFAR R IAD GA+L+ DMAH +GLVA SP Y DV+T+T Sbjct: 167 PRLIIAGGSAYPRHYDFARFRRIADAVGAMLLVDMAHFAGLVAGGCFPSPLAYADVITAT 226 Query: 1321 THKNLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIA 1500 THK LRGPRGG+I ND KI+ A+FP LQGGP + IA Sbjct: 227 THKTLRGPRGGMIL------------------TNDARLAKKIDSAIFPGLQGGPLMHVIA 268 Query: 1501 ALAITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTG 1680 A A+ L + PE+K Y QV++NAQA+ L +R L+TGGTD HL + DLR GLTG Sbjct: 269 AKAVALGEALQPEFKRYAGQVIENAQAMCQQLAQRGLTLLTGGTDCHLGIIDLRPQGLTG 328 Query: 1681 KNFEKVCELCHISINKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 E EL I++NK + GD S G+RIG+ A TRG DDF +IAD++ Sbjct: 329 AQVEYFLELAGITVNKNTLLGDPQPPSITSGIRIGSAACATRGMKADDFTLIADWI 384
>Q2RTB8:GLYA2_RHORT Serine hydroxymethyltransferase 2 - Rhodospirillum rubrum (strain| ATCC 11170 / NCIB 8255) Length = 430 Score = 313 bits (801), Expect = 3e-84 Identities = 183/407 (44%), Positives = 235/407 (57%), Gaps = 1/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ADP++ ++ E RQ IELIASEN V RAVL+A GS LTNKY+EG+PG RYYGG Sbjct: 15 VAQADPELDRVLRAELSRQQDQIELIASENIVSRAVLEAAGSVLTNKYAEGYPGKRYYGG 74 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E L +RA FG C VNVQP+S AN AV L+ P D IMG+ + Sbjct: 75 CEEVDVAEELAIERAKALFG----CSYVNVQPHSGAQANGAVMMALVKPGDTIMGMSLAA 130 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG K +F ++ Y V Q ID+D++ A PK++I GGS+ Sbjct: 131 GGHLTHGAPPAQSGK------WFNAVQYGVRLQDASIDFDEVATLAETHKPKLIIAGGSA 184 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DFA+ R IAD+ GA+ M DMAH +GLVAA SP Y D+VT+TTHK LRGPRG Sbjct: 185 YPRIIDFAKFREIADRVGALFMVDMAHFAGLVAAGLHPSPLPYADIVTTTTHKTLRGPRG 244 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G++ N+ D KIN AVFP LQGGP + IAA A+ + Sbjct: 245 GMVL------------------SNNPDIGKKINSAVFPGLQGGPLMHIIAAKAVAFGEAL 286 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y Q V+ NA+AL AL +V+GGTD HL L DLR LTG EK E Sbjct: 287 RPEFKVYAQAVIDNAKALTDALAAGGLNIVSGGTDTHLALVDLRPKALTGNIVEKSLERA 346 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 +I+ NK I + G+R+GTPA TTRG +F I ++ Sbjct: 347 NITTNKNGIPFDPEKPAITSGIRVGTPAGTTRGFGTAEFTEIGKLIV 393
>Q9HTE9:GLYA1_PSEAE Serine hydroxymethyltransferase 1 - Pseudomonas aeruginosa| Length = 417 Score = 313 bits (801), Expect = 3e-84 Identities = 177/402 (44%), Positives = 241/402 (59%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D ++ A M+ E RQ +ELIASEN+ + V+ A GS LTNKY+EG+PG RYYGG +H+ Sbjct: 12 DDELLAAMDAEEARQEDHLELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +ERL RA FG D A NVQP+S +SAN AVY LL D I+G+ GGH+ Sbjct: 72 DKVERLAIDRARQLFGADYA----NVQPHSGSSANAAVYLALLNAGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KVS + + ++ Y ++ TG IDYD++E A++ PK+++ G S+Y + Sbjct: 128 THG------AKVSSSGKLYNAVQYGLDTATGLIDYDEVERLAVEHKPKMIVAGFSAYSKT 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF R R IADK GA+L DMAH++GLVAA +P + DVVT+TTHK LRGPRGG+I Sbjct: 182 LDFPRFRAIADKVGALLFVDMAHVAGLVAAGLYPNPIPFADVVTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 R + + E K+N AVFP QGGP + IAA A+ K+ P + Sbjct: 242 ARANE-----------------EIEKKLNSAVFPGAQGGPLMHVIAAKAVCFKEALEPGF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y QV++NA+A+A + R +V+GGTDNHL+L L GLTGK + I++ Sbjct: 285 KDYQAQVIRNAKAMAEVFIGRGYDVVSGGTDNHLMLISLVRQGLTGKEADAALGRVGITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + D S G+RIGTPA+TTRG E +A ++ Sbjct: 345 NKNAVPNDPQSPFVTSGIRIGTPAITTRGLQEAQSRELAGWI 386
>Q48CP3:GLYA2_PSE14 Serine hydroxymethyltransferase 2 - Pseudomonas syringae pv.| phaseolicola (strain 1448A / Race 6) Length = 417 Score = 312 bits (799), Expect = 4e-84 Identities = 177/389 (45%), Positives = 234/389 (60%), Gaps = 1/389 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + + M E RQ IELIASEN+ + V+ A GS LTNKY+EG+PG RYYGG +H+ Sbjct: 12 DDALLSAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E+L +RA FG D A NVQP+S + AN AVY LL D ++G+ GGH+ Sbjct: 72 DKVEQLAIERAKQLFGADYA----NVQPHSGSQANAAVYLALLQAGDTVLGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KVS + + ++ Y ++ TG IDYD++E A++ PK++I G S+Y + Sbjct: 128 THG------AKVSFSGKLYNAVQYGIDTTTGLIDYDEVERIAVECQPKMIIAGFSAYSKT 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF R R IADK GA L DMAH++GLVAA +P Y DVVT+TTHK LRGPRGG+I Sbjct: 182 LDFPRFREIADKVGAYLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 + + + K K N AVFP QGGP + IAA A+ K+ P + Sbjct: 242 AKANEELEK-----------------KFNSAVFPGGQGGPLMHVIAAKAVCFKEAMEPGF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 KAY QQV+ NAQA+A + R +V+GGTDNHL L L GLTGK+ + HI++ Sbjct: 285 KAYQQQVIDNAQAMAQVFIDRGFDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRG 1806 NK + D S G+RIGTPA+TTRG Sbjct: 345 NKNSVPNDPQSPFVTSGLRIGTPAVTTRG 373
>Q88AD1:GLYA1_PSESM Serine hydroxymethyltransferase 1 - Pseudomonas syringae pv. tomato| Length = 417 Score = 312 bits (799), Expect = 4e-84 Identities = 177/389 (45%), Positives = 232/389 (59%), Gaps = 1/389 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + + M E RQ IELIASEN+ + V+ A GS LTNKY+EG+PG RYYGG +H+ Sbjct: 12 DDALLSAMNAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E+L +RA FG D A NVQP+S + AN AVY LL D ++G+ GGH+ Sbjct: 72 DKVEQLAIERARQLFGADYA----NVQPHSGSQANAAVYLALLQAGDTVLGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KVS + + ++ Y ++ TG IDYD++E A++ PK+LI G S+Y + Sbjct: 128 THG------AKVSFSGKLYNAVQYGIDTTTGLIDYDEVERIAVECQPKMLIAGFSAYSKT 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF R R IADK GA L DMAH++GLVAA +P Y DVVT+TTHK LRGPRGG+I Sbjct: 182 LDFPRFRAIADKVGAYLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 + + + K K N AVFP QGGP + IAA A+ K+ P + Sbjct: 242 AKANEELEK-----------------KFNSAVFPGGQGGPLMHVIAAKAVCFKEAMEPGF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y QQV+ NAQA+A + R +V+GGTDNHL L L GLTGK + HI++ Sbjct: 285 KTYQQQVIDNAQAMAQVFITRGFDVVSGGTDNHLFLVSLIRQGLTGKEADAALGRAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRG 1806 NK + D S G+RIGTPA+TTRG Sbjct: 345 NKNSVPNDPQSPFVTSGLRIGTPAVTTRG 373
>Q8PCN4:GLYA_XANCP Serine hydroxymethyltransferase - Xanthomonas campestris pv.| campestris Length = 417 Score = 311 bits (796), Expect = 1e-83 Identities = 179/402 (44%), Positives = 244/402 (60%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP++ + E RQ +ELIASEN+ V++A GS LTNKY+EG+PG RYYGG + + Sbjct: 12 DPELAKAIAAEAGRQEDHVELIASENYCSPLVMEAQGSQLTNKYAEGYPGKRYYGGCEFV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E+L R FG D A NVQP+S + AN AVY LL P D I+G+ GGH+ Sbjct: 72 DIAEQLAIDRIKQVFGADYA----NVQPHSGSQANQAVYLALLQPGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KV+ + F ++ Y VN Q G IDYD+++ A + PK++I G S+Y ++ Sbjct: 128 THG------AKVNASGKLFNAVQYGVNEQ-GLIDYDEVQRLATEHKPKMVIAGFSAYSQK 180 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 D+AR R IAD GA L DMAH++GLVAA SP D+ VVTSTTHK LRGPRGGII Sbjct: 181 IDWARFRAIADSVGAYLFVDMAHVAGLVAAGVYPSPMDHAHVVTSTTHKTLRGPRGGII- 239 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 + K G D K+ VFP +QGGP + IAA A+ K+ PE+ Sbjct: 240 ------LAKGAGE---------DLVKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPEF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y QQV+KNAQA+A+ L+ R ++V+GGT+NHL+L D+ ++GK+ E HI++ Sbjct: 285 KTYQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + D S G+R+GTPA+TTRG E D +A+++ Sbjct: 345 NKNSVPNDPRSPFVTSGLRLGTPAITTRGYQEQDCVDLANWI 386
>Q4UQT6:GLYA_XANC8 Serine hydroxymethyltransferase - Xanthomonas campestris pv.| campestris (strain 8004) Length = 417 Score = 311 bits (796), Expect = 1e-83 Identities = 179/402 (44%), Positives = 244/402 (60%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP++ + E RQ +ELIASEN+ V++A GS LTNKY+EG+PG RYYGG + + Sbjct: 12 DPELAKAIAAEAGRQEDHVELIASENYCSPLVMEAQGSQLTNKYAEGYPGKRYYGGCEFV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E+L R FG D A NVQP+S + AN AVY LL P D I+G+ GGH+ Sbjct: 72 DIAEQLAIDRIKQVFGADYA----NVQPHSGSQANQAVYLALLQPGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KV+ + F ++ Y VN Q G IDYD+++ A + PK++I G S+Y ++ Sbjct: 128 THG------AKVNASGKLFNAVQYGVNEQ-GLIDYDEVQRLATEHKPKMVIAGFSAYSQK 180 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 D+AR R IAD GA L DMAH++GLVAA SP D+ VVTSTTHK LRGPRGGII Sbjct: 181 IDWARFRAIADSVGAYLFVDMAHVAGLVAAGVYPSPMDHAHVVTSTTHKTLRGPRGGII- 239 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 + K G D K+ VFP +QGGP + IAA A+ K+ PE+ Sbjct: 240 ------LAKGAGE---------DLVKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPEF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y QQV+KNAQA+A+ L+ R ++V+GGT+NHL+L D+ ++GK+ E HI++ Sbjct: 285 KTYQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + D S G+R+GTPA+TTRG E D +A+++ Sbjct: 345 NKNSVPNDPRSPFVTSGLRLGTPAITTRGYQEQDCVDLANWI 386
>Q7MAR0:GLYA_WOLSU Serine hydroxymethyltransferase - Wolinella succinogenes| Length = 416 Score = 311 bits (796), Expect = 1e-83 Identities = 179/429 (41%), Positives = 253/429 (58%), Gaps = 1/429 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L D ++ L+ E DRQ +E+IASENF AV++A+GS LTNKY+EG+P RY Sbjct: 2 NYALETNDKEIFDLIHEELDRQNTHLEMIASENFTFPAVMEAMGSVLTNKYAEGYPYKRY 61 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + +D +E + +RA FG C NVQP++ + AN+AVY LL P D+I+G++ Sbjct: 62 YGGCEFVDRVEEIAIERAKKLFG----CGFANVQPHAGSQANVAVYNALLKPYDKILGMD 117 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG KVS ++S Y V GYI+YDK+E+ A P++++CG Sbjct: 118 LSHGGHLTHG------AKVSVTGQTYQSFFYGVELD-GYINYDKVEEIAKIVKPQMIVCG 170 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y RE DF R R IAD GA+L+ D+AH++GL+ A E +PF +C +VT+TTHK LRG Sbjct: 171 FSAYARELDFKRFREIADSVGALLLGDVAHVAGLIVAGEYPNPFPHCHIVTTTTHKTLRG 230 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I ND + KI+ AVFP +QGGP + IAA A+ Sbjct: 231 PRGGMIL------------------TNDEEIAKKIDKAVFPGMQGGPLMHVIAAKAVGFG 272 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+K Y +QV NA+ LA L+ R LV+GGTDNHL+L L +GK+ ++ Sbjct: 273 ENLKPEWKEYAKQVKANAKVLAKVLMARGYTLVSGGTDNHLILVSLLDKEFSGKDADRAL 332 Query: 1702 ELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVL 1878 I++NK + G+ S GVRIG+ A+T RG E +FE IA + + Sbjct: 333 GEAGITVNKNTVPGETRSPFVTSGVRIGSAALTARGMREKEFEFIATKIADVLDDVNNAA 392 Query: 1879 KQHGKVQKE 1905 K H +++KE Sbjct: 393 K-HAEIKKE 400
>Q46HB6:GLYA_PROMT Serine hydroxymethyltransferase - Prochlorococcus marinus (strain| NATL2A) Length = 411 Score = 311 bits (796), Expect = 1e-83 Identities = 177/409 (43%), Positives = 248/409 (60%), Gaps = 5/409 (1%) Frame = +1 Query: 637 EADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQ 816 + DP + L+ E RQ +ELIASENF +AV++A GS LTNKY+EG P RYYGG + Sbjct: 2 KCDPSIAKLINNELSRQETHLELIASENFASKAVMEAQGSVLTNKYAEGLPNKRYYGGCE 61 Query: 817 HIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGG 996 ++D +E+L RA FG A W NVQP+S AN AV+ LL P D IMG++ GG Sbjct: 62 YVDGVEQLAIDRAKNLFG---ANWA-NVQPHSGAQANFAVFLSLLKPGDTIMGMDLSHGG 117 Query: 997 HVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYP 1176 H++HG S VSG +F++ Y+V+ +T +D D + +A++ PK++ICG S+YP Sbjct: 118 HLTHG----SPVNVSGK--WFKTCHYEVDKKTEMLDMDAIRKKAIENQPKLIICGFSAYP 171 Query: 1177 REWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGI 1356 R+ DF R IAD+ A L+ D+AHI+GLVA+ SP YCDVVT+TTHK LRGPRGG+ Sbjct: 172 RKIDFKAFRSIADEVNAYLLADIAHIAGLVASGLHPSPIPYCDVVTTTTHKTLRGPRGGL 231 Query: 1357 IFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATP 1536 I D + K++ AVFP QGGP + IAA A+ K+ + P Sbjct: 232 IL------------------SKDKEIGKKLDKAVFPGTQGGPLEHVIAAKAVAFKEASAP 273 Query: 1537 EYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHI 1716 E+K Y Q+V+ NA+ L++ L +R +V+ GTDNH+VL DLR+ G+TGK +++ I Sbjct: 274 EFKIYSQKVISNAKVLSNQLQKRGISIVSKGTDNHIVLLDLRSIGMTGKVADQLVSDIKI 333 Query: 1717 SINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDF----EVIADFLI 1848 + NK + + G+R+G+ A+TTRG E F VIAD L+ Sbjct: 334 TANKNTVPFDPESPFVTSGLRLGSAALTTRGFNEQAFGDVGNVIADRLL 382
>Q3K6J0:GLYA2_PSEPF Serine hydroxymethyltransferase 2 - Pseudomonas fluorescens (strain| PfO-1) Length = 417 Score = 311 bits (796), Expect = 1e-83 Identities = 177/406 (43%), Positives = 245/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D D+ A ME+E RQ IELIASEN+ AV++A GS LTNKY+EG+PG RYYGG Sbjct: 8 IAKYDADLFAAMEQEAQRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP++ + AN AVY LL D I+G+ Sbjct: 68 CEYVDVVEQLAIDRAKELFGADYA----NVQPHAGSQANAAVYLALLSAGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG VS + + ++ Y ++ G IDYD++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG------ASVSSSGKLYNAIQYGIDAN-GLIDYDEVERLAVEHKPKMIVAGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + DF R R IADK GA L DMAH++GLVAA +P + DVVT+TTHK LRGPRG Sbjct: 177 YSQILDFPRFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + + D E K+N AVFP QGGP + IAA AI K+ Sbjct: 237 GLILAKA-----------------NADIEKKLNSAVFPGAQGGPLEHVIAAKAICFKEAL 279 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+KAY QQV+KNAQA+A + R +V+GGT+NHL L L ++GK+ + Sbjct: 280 QPEFKAYQQQVVKNAQAMAGVFIERGFDVVSGGTENHLFLLSLIKQEISGKDADAALGKA 339 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK + D S G+R GTPA+TTRG E + + +A ++ Sbjct: 340 FITVNKNSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELAGWI 385
>Q607U4:GLYA_METCA Serine hydroxymethyltransferase - Methylococcus capsulatus| Length = 418 Score = 310 bits (795), Expect = 1e-83 Identities = 172/406 (42%), Positives = 245/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A D ++ A ++ E RQ IELIASEN+ VL A G+ LTNKY+EG+PG RYYGG Sbjct: 8 IAGFDDELWAAIQEEERRQEDHIELIASENYASPRVLQAQGTVLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E L +RA FG D A NVQP+S + AN AVY LL P D ++G+ Sbjct: 68 CEYVDIVETLAIERAKRLFGADYA----NVQPHSGSQANAAVYMALLKPGDTVLGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG KV+ + + ++ Y +NP+TG IDYD++++ A + PK+++ G S+ Sbjct: 124 GGHLTHG------AKVNFSGKIYNAVQYGLNPETGEIDYDQVDELAREHRPKMIVAGFSA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + D+ R R IAD GA LM DMAH++GL+AA SP DV T+TTHK LRGPRG Sbjct: 178 YSQVVDWQRFRAIADSVGAWLMVDMAHVAGLIAAGLYPSPVQIADVTTTTTHKTLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + + K ++N VFP +QGGP + IAA A+ LK+ Sbjct: 238 GLILAKANPEVEK-----------------QLNSLVFPGIQGGPLMHVIAAKAVALKEAL 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P+++ Y VM+NA A+A + R R+V+GGT NHL L DL GLTGK E+V Sbjct: 281 QPDFRHYQSAVMENADAMAKTFIERGYRIVSGGTRNHLFLVDLIQKGLTGKLAEEVLGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK + D S G+R+GTPA+TTRG ++ ++A ++ Sbjct: 341 HITVNKNAVPNDPQSPFVTSGIRVGTPAVTTRGFGVEECRLLAGWM 386
>Q5WYH4:GLYA_LEGPL Serine hydroxymethyltransferase - Legionella pneumophila (strain| Lens) Length = 417 Score = 310 bits (794), Expect = 2e-83 Identities = 177/392 (45%), Positives = 235/392 (59%), Gaps = 1/392 (0%) Frame = +1 Query: 673 ERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHIDAIERLCHQR 852 E+ RQ IELIASEN+V VL+A GS LTNKY+EG+PG RYYGG + +D E L R Sbjct: 22 EKRRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGGCEFVDVAEELAISR 81 Query: 853 ALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHVSHGYYTPSGK 1032 A FG VNVQP+S + AN AV LL P D MG+ P GGH++HG Sbjct: 82 AKLLFGAHY----VNVQPHSGSQANAAVMMALLSPGDTFMGMALPHGGHLTHG------S 131 Query: 1033 KVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPREWDFARMRLIA 1212 KV+ + + S+ Y V+ TG IDYD LE A+ PK++I G S+Y R D+AR R IA Sbjct: 132 KVNFSGKLYHSVEYGVDNNTGLIDYDALEKLALQHKPKLIIAGFSAYSRILDWARFREIA 191 Query: 1213 DKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIFFRKGKNMRKR 1392 DK GA LM D+AH++GLVA SP Y DVVT+TTHK LRGPRGG+I ++ + Sbjct: 192 DKVGAYLMADIAHVAGLVAVGLYPSPVPYADVVTTTTHKTLRGPRGGLILCKENE----- 246 Query: 1393 GGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEYKAYIQQVMKN 1572 + E K+N AVFP +QGGP + IAA A+ + PE+K Y QQV+ N Sbjct: 247 ------------EIEKKLNSAVFPGMQGGPLMHVIAAKAVAFAEALLPEFKTYQQQVLAN 294 Query: 1573 AQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISINKTPIYGDNG 1752 A+ + S L R +V+GGTDNHL+L DL G+TGK + +I++NK + D Sbjct: 295 ARTMCSVLQSRGYDIVSGGTDNHLLLVDLINKGITGKEADAALGRANITVNKNSVPNDPR 354 Query: 1753 S-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 S G+R+GTPA TTRG E + ++++++ Sbjct: 355 SPFVTSGLRLGTPAATTRGFKEREITLLSNWV 386
>Q65DW5:GLYA_BACLD Serine hydroxymethyltransferase - Bacillus licheniformis (strain DSM| 13 / ATCC 14580) Length = 415 Score = 310 bits (794), Expect = 2e-83 Identities = 183/453 (40%), Positives = 257/453 (56%), Gaps = 1/453 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L D V + ++ ER RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 LPAQDEQVFSAIQDERKRQQSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D E + RA FG + VNVQP+S AN+AVY +L D ++G+ Sbjct: 64 CEHVDVAEDIARDRAKQIFGAEH----VNVQPHSGAQANMAVYFTILEHGDTVLGMNLAH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + + Y V+ +T YIDY+ + ++A+ PK+++ G S+ Sbjct: 120 GGHLTHG------SPVNFSGVQYNFVEYGVDKETQYIDYEDVREKALKHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF + R IAD+ GA +M DMAHI+GLVAA +P Y D VT+TTHK LRGPRG Sbjct: 174 YPRTIDFKKFREIADEVGAYVMVDMAHIAGLVAAGLHPNPVPYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R+ +F +I+ ++FP +QGGP + IAA A++ + Sbjct: 234 GMILCRE-------------------EFAKQIDKSIFPGIQGGPLMHVIAAKAVSFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 E+K Y Q V+ NA+ LA L + LV+GGTDNHLVL DLR+ G+TGK E V + Sbjct: 275 KDEFKTYAQNVINNAKRLAETLKKEGIELVSGGTDNHLVLVDLRSLGITGKVAENVLDEV 334 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I++NK I Y G+R+GT A+T+RG D E I + I LK H Sbjct: 335 GITVNKNAIPYDPEKPFVTSGIRVGTAAVTSRGF---DLEAIEE----VGAIIALALKNH 387 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 E+ + E +VEA ++F + Sbjct: 388 -----------EDEAKLEEAKQRVEALTNRFPL 409
>Q7V335:GLYA_PROMP Serine hydroxymethyltransferase - Prochlorococcus marinus subsp.| pastoris (strain CCMP 1378 / MED4) Length = 423 Score = 310 bits (793), Expect = 2e-83 Identities = 176/413 (42%), Positives = 249/413 (60%), Gaps = 5/413 (1%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 Q L E+DP + L+ E++RQ +ELIASENF AV+ A GS LTNKY+EG P RYY Sbjct: 5 QNLKESDPIISNLINSEKNRQETHLELIASENFASMAVMQAQGSVLTNKYAEGLPQKRYY 64 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG + +D IE L +RA F D A NVQP+S AN AV+ LL P D I+G++ Sbjct: 65 GGCEFVDEIEELAIERAKQLFDADWA----NVQPHSGAQANAAVFLSLLKPGDTILGMDL 120 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 GGH++HG V+ + +F ++ Y V+ +T ++++++ D A+ PK++ICG Sbjct: 121 SHGGHLTHG------SPVNMSGKWFNAVHYGVDKETNKLNFNEIRDIALATKPKLIICGY 174 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S+YPR+ DF R IAD+ GA LM D+AHI+GLVA K +P YCDVVT+TTHK LRGP Sbjct: 175 SAYPRKIDFESFRRIADEVGAFLMADIAHIAGLVATKLHPNPIPYCDVVTTTTHKTLRGP 234 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 RGG+I + D +F K + +VFP QGGP + IAA A+ + Sbjct: 235 RGGLILCK------------------DKEFGKKFDKSVFPGTQGGPLEHIIAAKAVAFGE 276 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 P + Y +QV+ NA+ L+S L++R +V+GGTDNH+VL DLR+ +TGK + + Sbjct: 277 ALKPNFVNYSKQVINNAKVLSSTLIKRGIDIVSGGTDNHIVLLDLRSINMTGKVADLLVS 336 Query: 1705 LCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDF----EVIADFLI 1848 +I+ NK + + G+R+GT A+TTRG +D F E+IAD L+ Sbjct: 337 EVNITANKNTVPFDPESPFVTSGLRLGTAALTTRGFNDDAFVEVGEIIADRLL 389
>Q7VDS8:GLYA_PROMA Serine hydroxymethyltransferase - Prochlorococcus marinus| Length = 419 Score = 310 bits (793), Expect = 2e-83 Identities = 181/420 (43%), Positives = 246/420 (58%), Gaps = 5/420 (1%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L DPD+ L+ +E RQ +ELIASENF AV++A GS LTNKY+EG P RY Sbjct: 5 NSDLRNTDPDISFLINQELLRQQTHLELIASENFASEAVMEAQGSVLTNKYAEGLPNKRY 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +HIDAIE+L RA T F + A NVQP+S AN AV+ LL P D IMG++ Sbjct: 65 YGGCEHIDAIEQLAITRAQTLFNAEWA----NVQPHSGAQANFAVFLALLNPGDTIMGMD 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG S VSG +F ++ Y V+ T ++++++ A+ PK++ICG Sbjct: 121 LSHGGHLTHG----SPVNVSGK--WFNAIHYGVDQTTKVLNFEQIRQVALKNRPKLIICG 174 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR DF R IAD+ A L+ D+AHI+GLVA +P YCDVVT+TTHK LRG Sbjct: 175 FSAYPRTIDFKAFRSIADEIDAYLLADIAHIAGLVACGAHPNPVPYCDVVTTTTHKTLRG 234 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I R D +F + + AVFP QGGP + IAA A+ Sbjct: 235 PRGGLILCR------------------DKEFGKRFDKAVFPGNQGGPLEHVIAAKAVAFG 276 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+K Y QV+ NA+ALA + R +V+ GTDNH+VL DLR+ +TGK + + Sbjct: 277 EALKPEFKTYTFQVISNAKALAKRIQERGISIVSEGTDNHIVLLDLRSIEMTGKKADSLI 336 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDF----EVIADFLIRATQIA 1866 +I+ NK + + G+R+GT A+TTRG E F +VIAD L+ ++ Sbjct: 337 SEVNITANKNTVPFDPESPFVTSGLRLGTAALTTRGFTEKAFIEVADVIADCLLNPEDLS 396
>Q9HVI7:GLYA3_PSEAE Serine hydroxymethyltransferase 3 - Pseudomonas aeruginosa| Length = 417 Score = 310 bits (793), Expect = 2e-83 Identities = 178/406 (43%), Positives = 243/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA D ++ A ME+E RQ IELIASEN+ AV++A GS LTNKY+EG+P RYYGG Sbjct: 8 LARYDAELFAAMEQEAQRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPHKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP++ + AN AVY LL D I+G+ Sbjct: 68 CEYVDIVEQLAIDRAKQLFGADYA----NVQPHAGSQANAAVYLALLSAGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG VS + + ++ Y ++ G IDYD++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG------ASVSSSGKLYNAVQYGIDAN-GLIDYDEVERLAVEHKPKMIVAGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + DFAR R IADK GA L DMAH++GLVAA +P + DVVT+TTHK LRGPRG Sbjct: 177 YSQVLDFARFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R + + E K+N AVFPS QGGP + IAA A+ K+ Sbjct: 237 GLILARANE-----------------EIEKKLNSAVFPSAQGGPLEHVIAAKAVCFKEAL 279 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV+KNAQ++A L R +V+GGT NHL L L +TGK+ + Sbjct: 280 QPEFKTYQQQVLKNAQSMAQVFLDRGFDVVSGGTQNHLFLLSLIKQDITGKDADAALGRA 339 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK + D S G+RIGTPA+TTRG E + +A ++ Sbjct: 340 FITVNKNSVPNDPRSPFVTSGLRIGTPAVTTRGFKEAECRELAGWI 385
>Q5ZXK6:GLYA_LEGPH Serine hydroxymethyltransferase - Legionella pneumophila subsp.| pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) Length = 417 Score = 309 bits (792), Expect = 3e-83 Identities = 176/392 (44%), Positives = 235/392 (59%), Gaps = 1/392 (0%) Frame = +1 Query: 673 ERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHIDAIERLCHQR 852 E+ RQ IELIASEN+V VL+A GS LTNKY+EG+PG RYYGG + +D E L R Sbjct: 22 EKRRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGGCEFVDVAEELAISR 81 Query: 853 ALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHVSHGYYTPSGK 1032 A FG VNVQP+S + AN AV LL P D MG+ P GGH++HG Sbjct: 82 AKLLFGAHY----VNVQPHSGSQANAAVMMALLSPGDTFMGMALPHGGHLTHG------S 131 Query: 1033 KVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPREWDFARMRLIA 1212 KV+ + + S+ Y V+ TG IDYD LE A+ PK++I G S+Y R D+AR R IA Sbjct: 132 KVNFSGKLYHSVEYGVDSNTGLIDYDALEKLALQHKPKLIIAGFSAYSRILDWARFREIA 191 Query: 1213 DKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIFFRKGKNMRKR 1392 DK GA LM D+AH++GLVA SP Y DVVT+TTHK LRGPRGG+I ++ + Sbjct: 192 DKVGAYLMADIAHVAGLVAVGLYPSPVPYADVVTTTTHKTLRGPRGGLILCKENE----- 246 Query: 1393 GGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEYKAYIQQVMKN 1572 + E K+N +VFP +QGGP + IAA A+ + PE+K Y QQV+ N Sbjct: 247 ------------EIEKKLNSSVFPGMQGGPLMHVIAAKAVAFAEALLPEFKTYQQQVLAN 294 Query: 1573 AQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISINKTPIYGDNG 1752 A+ + S L R +V+GGTDNHL+L DL G+TGK + +I++NK + D Sbjct: 295 ARTMCSVLQSRGYDIVSGGTDNHLLLVDLINKGITGKEADAAVGRANITVNKNSVPNDPR 354 Query: 1753 S-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 S G+R+GTPA TTRG E + ++++++ Sbjct: 355 SPFVTSGLRLGTPAATTRGFKEREITLLSNWV 386
>Q5X722:GLYA_LEGPA Serine hydroxymethyltransferase - Legionella pneumophila (strain| Paris) Length = 417 Score = 309 bits (792), Expect = 3e-83 Identities = 176/392 (44%), Positives = 235/392 (59%), Gaps = 1/392 (0%) Frame = +1 Query: 673 ERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHIDAIERLCHQR 852 E+ RQ IELIASEN+V VL+A GS LTNKY+EG+PG RYYGG + +D E L R Sbjct: 22 EKRRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGGCEFVDVAEELAISR 81 Query: 853 ALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHVSHGYYTPSGK 1032 A FG VNVQP+S + AN AV LL P D MG+ P GGH++HG Sbjct: 82 AKLLFGAHY----VNVQPHSGSQANAAVMMALLSPGDTFMGMALPHGGHLTHG------S 131 Query: 1033 KVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPREWDFARMRLIA 1212 KV+ + + S+ Y V+ TG IDYD LE A+ PK++I G S+Y R D+AR R IA Sbjct: 132 KVNFSGKLYHSVEYGVDSNTGLIDYDALEKLALQHKPKLIIAGFSAYSRILDWARFREIA 191 Query: 1213 DKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIFFRKGKNMRKR 1392 DK GA LM D+AH++GLVA SP Y DVVT+TTHK LRGPRGG+I ++ + Sbjct: 192 DKVGAYLMADIAHVAGLVAVGLYPSPVPYADVVTTTTHKTLRGPRGGLILCKENE----- 246 Query: 1393 GGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEYKAYIQQVMKN 1572 + E K+N +VFP +QGGP + IAA A+ + PE+K Y QQV+ N Sbjct: 247 ------------EIEKKLNSSVFPGMQGGPLMHVIAAKAVAFAEALLPEFKTYQQQVLAN 294 Query: 1573 AQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISINKTPIYGDNG 1752 A+ + S L R +V+GGTDNHL+L DL G+TGK + +I++NK + D Sbjct: 295 ARTMCSVLQSRGYDIVSGGTDNHLLLVDLINKGITGKEADAAVGRANITVNKNSVPNDPR 354 Query: 1753 S-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 S G+R+GTPA TTRG E + ++++++ Sbjct: 355 SPFVTSGLRLGTPAATTRGFKEREITLLSNWV 386
>Q3APN5:GLYA_CHLCH Serine hydroxymethyltransferase - Chlorobium chlorochromatii (strain| CaD3) Length = 438 Score = 309 bits (792), Expect = 3e-83 Identities = 178/412 (43%), Positives = 241/412 (58%), Gaps = 7/412 (1%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + D +V A + E RQ +ELIASENF RAV+ A GS +TNKY+EG+PG RYYGG Sbjct: 6 LQKQDAEVFASIANETKRQTETLELIASENFTSRAVMQACGSVMTNKYAEGYPGKRYYGG 65 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E L RA FG C VNVQP+S +SAN+AV +L P D+IMGL+ Sbjct: 66 CEFVDVAENLARDRAKKLFG----CEYVNVQPHSGSSANMAVLFSVLKPGDKIMGLDLSH 121 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + FE+ SY V+ +TG ID +K+E+ AM PK++I G S+ Sbjct: 122 GGHLTHG------SSVNFSGQMFEAHSYGVDRETGCIDMNKVEEMAMQVRPKLIIGGASA 175 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + +DF R IADK GA+LM D+AH +GL+AA +P +C VT+TTHK LRGPRG Sbjct: 176 YSQGFDFKAFRAIADKVGALLMADIAHPAGLIAAGLLPNPLQHCHFVTTTTHKTLRGPRG 235 Query: 1351 GIIFFRK------GKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAI 1512 G+I G ++ + GS + D E V P +QGGP + IA A+ Sbjct: 236 GMIMMGSDFENPLGITIKTKTGSRVKMMSEVMDAE------VMPGIQGGPLMHIIAGKAV 289 Query: 1513 TLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFE 1692 + P +K Y QVMKNA +AS + +V+GGT NHL+L DLR +TGK E Sbjct: 290 AFGEALQPAFKEYAAQVMKNASTMASRFMELGYTIVSGGTKNHLMLLDLRNKNVTGKEAE 349 Query: 1693 KVCELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 + I++NK + + D G+RIGTPAMTTRG E + IA+ + Sbjct: 350 NLLHEAGITVNKNMVPFDDKSPFVTSGIRIGTPAMTTRGMKEAESRRIAELI 401
>Q3MBD8:GLYA_ANAVT Serine hydroxymethyltransferase - Anabaena variabilis (strain ATCC| 29413 / PCC 7937) Length = 427 Score = 309 bits (792), Expect = 3e-83 Identities = 181/411 (44%), Positives = 246/411 (59%), Gaps = 5/411 (1%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L +DP + L+ +E RQ +ELIASENF AVL A GS LTNKY+EG PG RYYGG Sbjct: 9 LTNSDPAIAGLINQELQRQRDHLELIASENFTSAAVLAAQGSVLTNKYAEGLPGKRYYGG 68 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + ID IE++ RA FG A NVQP+S AN AV+ LL P D+IMG++ Sbjct: 69 CEFIDKIEQIAIDRAKQLFGAAHA----NVQPHSGAQANFAVFLTLLAPGDKIMGMDLSH 124 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S VSG +F+ Y V+ QT +DYD++ + A+ PK+LICG S+ Sbjct: 125 GGHLTHG----SPVNVSGK--WFQVCHYGVSQQTEQLDYDQIRELALRERPKLLICGYSA 178 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF + R IAD+ GA L+ D+AHI+GLVA+ P YC VVT+TTHK LRGPRG Sbjct: 179 YPRIIDFEKFRSIADEVGAYLLADIAHIAGLVASGLHPDPIPYCHVVTTTTHKTLRGPRG 238 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I D + K++ +VFP QGGP + IA A+ + Sbjct: 239 GLIL------------------TGDAELGKKLDKSVFPGSQGGPLEHVIAGKAVAFGEAL 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE++ Y QV++NA+ALA+ L R +LV+ GTDNHL+L DLR+ +TGK +++ Sbjct: 281 KPEFQGYSAQVIENARALANQLQNRGLKLVSDGTDNHLMLVDLRSVNMTGKRADQLVSEV 340 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDF----EVIADFLI 1848 +I+ NK + + G+R+G+PAMTTRG E +F +IAD L+ Sbjct: 341 NITANKNTVPFDPQSPFVTSGLRLGSPAMTTRGMGEAEFTEIGNIIADRLL 391
>Q6N622:GLYA2_RHOPA Serine hydroxymethyltransferase 2 - Rhodopseudomonas palustris| Length = 434 Score = 309 bits (792), Expect = 3e-83 Identities = 185/407 (45%), Positives = 239/407 (58%), Gaps = 1/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L AD V A + E RQ IELIASENFV RAVLDA GS LTNKY+EG+P RYYGG Sbjct: 23 LVAADHAVAAAIADEETRQRDSIELIASENFVSRAVLDAQGSVLTNKYAEGYPHRRYYGG 82 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 ++DAIE L R FG A NVQP+S + AN AV+ LL P D I+GL+ + Sbjct: 83 CANVDAIEDLVIARVNQLFGSAYA----NVQPHSGSQANQAVFLALLAPGDTILGLDLKA 138 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F+++SY V+P+T ID D++ +A P++LI GGS+ Sbjct: 139 GGHLTHG------APVNMSGRWFKAVSYGVDPETHRIDMDQVAVQARQHRPRLLIAGGSA 192 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF R R IAD+ GA+LM DMAH +GLVA SP + DVVTSTTHK LRGPRG Sbjct: 193 YPRIIDFGRFRQIADEVGAILMVDMAHFAGLVAGGVYPSPVPFADVVTSTTHKTLRGPRG 252 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G + ND + KIN A FP LQGGP + IAA A+ + Sbjct: 253 GFVL------------------TNDANIAKKINSATFPGLQGGPLMHVIAAKAVAFGEAL 294 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+ AY Q V++N + LA AL + +GGTD HL + DLR FG+TG E+ E Sbjct: 295 QPEFGAYAQAVVENCRVLAQALADGGLTITSGGTDCHLAVVDLRPFGVTGNIAEQALESV 354 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 I++NK I D + G+R+GT A T+RG D + IA ++ Sbjct: 355 GITLNKNAIPNDPEKPMVTSGIRVGTAAGTSRGFGADQYREIAGLVL 401
>Q5NN85:GLYA_ZYMMO Serine hydroxymethyltransferase - Zymomonas mobilis| Length = 429 Score = 309 bits (791), Expect = 4e-83 Identities = 180/406 (44%), Positives = 238/406 (58%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA ADPDV + E +RQ + IELIASEN V RAVL+A GS TNKY+EG+PG RYY G Sbjct: 13 LAAADPDVLTAINHELNRQRKQIELIASENIVSRAVLEAQGSVFTNKYAEGYPGKRYYQG 72 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 D IE L +RA FG + VNVQP+S AN AV + P D IMGL + Sbjct: 73 CAPSDEIETLAIERAKKLFGSE----FVNVQPHSGAQANGAVLLAVAKPGDTIMGLSLDA 128 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG K + + +F ++ Y V+P+T IDYD++ D A+ P+++I GGS+ Sbjct: 129 GGHLTHG------AKAAMSGKWFNAVQYAVHPETQLIDYDQVRDLALKNKPRVIIAGGSA 182 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DFA R +AD+ GA M DMAH +GLVA SP + + T+TTHK LRGPRG Sbjct: 183 YPRHIDFAFFRKVADEVGATFMVDMAHFAGLVAGGVHPSPVPHAHITTTTTHKTLRGPRG 242 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I +D KIN AVFP +QGGP + IAA A+ + Sbjct: 243 GMIL------------------TDDPALAKKINSAVFPGMQGGPLMHVIAAKAVAFGEAL 284 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P +K Y + V++NAQALA+ L R LVTGGTD HL L DLR G+TG++ + E Sbjct: 285 QPSFKEYAKAVVENAQALAARLKERGSDLVTGGTDTHLALVDLRPLGVTGRDADCALERA 344 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + + G+R+G+PA TTRG + +F +AD + Sbjct: 345 GITCNKNGIPFDPLPPVKTSGIRLGSPAATTRGFRKAEFLQVADMI 390
>P50435:GLYA_METEX Serine hydroxymethyltransferase - Methylobacterium extorquens| (Protomonas extorquens) Length = 434 Score = 308 bits (790), Expect = 5e-83 Identities = 178/408 (43%), Positives = 234/408 (57%), Gaps = 1/408 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LAE DP++ + +E RQ IELIASEN V RAVL+A GS LTNKY+EG+PG RYYGG Sbjct: 20 LAETDPEIAKAISQELGRQQHEIELIASENIVSRAVLEAQGSVLTNKYAEGYPGRRYYGG 79 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 Q +D E L RA FG C NVQP S + AN V+ L+ P D +GL+ + Sbjct: 80 CQFVDIAEELAIDRAKRLFG----CGFANVQPNSGSQANQGVFMALMQPGDTFLGLDLAA 135 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG + VSG +F+ +SY V + ID +++E A + PK++I GGS Sbjct: 136 GGHLTHG----APPNVSGK--WFKPVSYTVRREDQRIDMEQVERLAQEHKPKVIIAGGSG 189 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR WDFA+ R IAD GA DMAH +GLVAA SPF + V T+TTHK LRGPRG Sbjct: 190 YPRHWDFAKFREIADSVGAYFFVDMAHFAGLVAAGLHPSPFPHAHVATTTTHKTLRGPRG 249 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ND K N A+FP LQGGP + IAA A + Sbjct: 250 GMIL------------------TNDEALAKKFNSAIFPGLQGGPLMHVIAAKAAAFGEAL 291 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y +QV+ NA+ALA ++ + +GGTDNHL+L DL+ GLTGK E Sbjct: 292 KPEFKIYAKQVIDNARALADTIISGGYDITSGGTDNHLMLVDLQKKGLTGKAAEAALSRA 351 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIR 1851 I+ NK + + G+R+GTPA TTRG +F+ + +++ Sbjct: 352 DITCNKNGVPFDPQKPTITSGIRLGTPASTTRGFGVAEFKQVGSLIVQ 399
>Q8XTQ1:GLYA2_RALSO Serine hydroxymethyltransferase 2 - Ralstonia solanacearum| (Pseudomonas solanacearum) Length = 424 Score = 308 bits (790), Expect = 5e-83 Identities = 181/410 (44%), Positives = 236/410 (57%), Gaps = 1/410 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +Q LAE D + + + +E +RQ +ELIASEN V RAVL+A GS LTNKY+EG+PG RY Sbjct: 9 SQSLAERDAPIRSSLLKELERQQSQVELIASENIVSRAVLEAQGSVLTNKYAEGYPGKRY 68 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG ++ D +E L R F A NVQP+S AN AV L P D ++G+ Sbjct: 69 YGGCEYADEVESLAIDRVKQLFNAGFA----NVQPHSGAQANGAVMLALTKPGDTVLGMS 124 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 +GGH++HG K + + +F ++ Y VN T IDY+++E A + P ++I G Sbjct: 125 LDAGGHLTHG------AKPALSGKWFNAMQYGVNRDTMLIDYEQVEKLAQEHKPSLIIAG 178 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR+ DFAR R IAD GA LM DMAHI+G++AA +P D+ VVTSTTHK LRG Sbjct: 179 FSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHDNPVDHAHVVTSTTHKTLRG 238 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG + ND + KIN AVFP LQGGP + IA A+ Sbjct: 239 PRGGFVL------------------TNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFG 280 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+K YI V+ NA+AL L LVTGGTDNHL+L DLR GL G E+ Sbjct: 281 EALKPEFKTYIDSVLANAKALGEVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGTQVEQAL 340 Query: 1702 ELCHISINKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 E I+ NK I D + G+R+GTPA TTRG +FE I ++ Sbjct: 341 ERAGITCNKNGIPFDTEKPTITSGIRLGTPAATTRGFGVAEFEQIGRLIL 390
>Q88Q27:GLYA2_PSEPK Serine hydroxymethyltransferase 2 - Pseudomonas putida (strain| KT2440) Length = 417 Score = 308 bits (790), Expect = 5e-83 Identities = 177/406 (43%), Positives = 245/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ M++E RQ IELIASEN+ AV++A GS LTNKY+EG+PG RYYGG Sbjct: 8 IAKYDAELFEAMQQEALRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP++ + AN AVY LL D I+G+ Sbjct: 68 CEYVDVVEQLAIDRAKELFGADYA----NVQPHAGSQANAAVYLALLSAGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG VS + + ++ Y ++ G IDYD++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG------ASVSSSGKLYNAIQYGIDGN-GLIDYDEVERLAVEHKPKMIVAGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + DFAR R IADK GA L DMAH++GLVAA +P + DVVT+TTHK LRGPRG Sbjct: 177 YSQVLDFARFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R + D E K+N AVFP QGGP + IAA AI K+ Sbjct: 237 GLILARA-----------------NADIEKKLNSAVFPGAQGGPLEHVIAAKAICFKEAL 279 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+KAY QQV+KNAQA+AS + R +V+GGT NHL L L ++GK+ + Sbjct: 280 QPEFKAYQQQVVKNAQAMASVFIERGFDVVSGGTQNHLFLLSLIKQEISGKDADAALGKA 339 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK + D S G+R GTPA+TTRG E + + +A ++ Sbjct: 340 FITVNKNSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELAGWI 385
>Q2SFI7:GLYA1_HAHCH Serine hydroxymethyltransferase 1 - Hahella chejuensis (strain KCTC| 2396) Length = 426 Score = 308 bits (790), Expect = 5e-83 Identities = 173/406 (42%), Positives = 244/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ DP++ A + E+ RQ IELIASEN+V V++A G LTNKY+EG+PG RYYGG Sbjct: 8 IADYDPELSAAINAEKRRQEEHIELIASENYVSPRVMEAQGGVLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D E+L RA FG D A NVQP+S + AN VY L P D I+G+ Sbjct: 68 CEHVDVAEQLAIDRAKQLFGADYA----NVQPHSGSQANAGVYLALAKPGDTILGMSLDH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG K + + F ++ Y +NP+TG IDYD++E A + PK++I G S+ Sbjct: 124 GGHLTHG------AKPNFSGKIFNAVQYGLNPETGEIDYDQVERLAKEHKPKLVIAGFSA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R D+ R R IAD GA L+ DMAH++GLVAA SP DV T+TTHK LRGPRG Sbjct: 178 YSRVVDWQRFRDIADSVGAYLIVDMAHVAGLVAAGLYPSPVQIADVTTTTTHKTLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++ + E K+ +FP +QGGP + IAA A+ K+ Sbjct: 238 GLILAK-----------------SNPEIEKKLQSLIFPGIQGGPLMHVIAAKAVAFKEAL 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P ++ Y QQV+ NA+A+A A+ R ++V+GGTDNHL L DL G+TGK+ + Sbjct: 281 EPAFRDYQQQVVNNARAMADAVKARGYKVVSGGTDNHLFLIDLIDKGVTGKDADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+RIGTP +TTRG E + +A+++ Sbjct: 341 YITVNKNTVPNDPQSPFVTSGLRIGTPGVTTRGFKEKEVVELANWI 386
>Q2FLH5:GLYA_METHJ Serine hydroxymethyltransferase - Methanospirillum hungatei (strain| JF-1 / DSM 864) Length = 414 Score = 308 bits (789), Expect = 6e-83 Identities = 172/406 (42%), Positives = 241/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L DP++ A++++E +RQ+ G+ELIASEN V RAVL+A GS +TNKY+EG+PG RYYGG Sbjct: 4 LETTDPEIAAIIDKETNRQINGLELIASENVVSRAVLEASGSIMTNKYAEGYPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + D E L R + FG + A NVQP+S + AN+AVY +L P+D+I+ + Sbjct: 64 CEFHDMAENLARDRVCSLFGAEHA----NVQPHSGSQANMAVYFTVLKPSDKILSMNLSQ 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH+SHG V+ + I +ES Y V+ +T +DY + + A PKI++CG S+ Sbjct: 120 GGHLSHG------SPVNFSGIIYESHQYGVDLKTERMDYGTIAEMARTIKPKIIVCGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPRE DF I+++ GA + D+AHI+GL A SP TSTTHK LRGPRG Sbjct: 174 YPREIDFKAFAEISEEVGAYCVADIAHIAGLCATGIHPSPVGLTTFTTSTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G I D +F I+ AVFP +QGGP + IAA A+ K+ + Sbjct: 234 GFILC-------------------DKEFAAPIDKAVFPGMQGGPLMHIIAAKAVCFKEAS 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 T E+K Y +QV+KNA+ +A L RLV+GGTDNHL L DL FG+TG E+ Sbjct: 275 TKEFKKYSEQVVKNARTMAETLSANGVRLVSGGTDNHLCLLDLTNFGITGLEAEQALGNA 334 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK I + S G+R+GTPA+T+RG E + + I +++ Sbjct: 335 GITVNKNTIPNETKSPFVTSGLRVGTPAVTSRGMKESEMKQIGEWI 380
>Q4K5R9:GLYA1_PSEF5 Serine hydroxymethyltransferase 1 - Pseudomonas fluorescens (strain| Pf-5 / ATCC BAA-477) Length = 417 Score = 308 bits (789), Expect = 6e-83 Identities = 177/406 (43%), Positives = 244/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D D+ A ME+E RQ IELIASEN+ AV++A GS LTNKY+EG+PG RYYGG Sbjct: 8 IAKYDADLFAAMEQEAQRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP++ + AN AVY LL D I+G+ Sbjct: 68 CEYVDVVEQLAIDRAKELFGADYA----NVQPHAGSQANAAVYLALLQGGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG VS + + ++ Y ++ G IDYD++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG------AAVSSSGKLYNAIQYGIDAN-GLIDYDEVERLAVEHKPKMIVAGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + DF R R IADK GA L DMAH++GLVAA +P + DVVT+TTHK LRGPRG Sbjct: 177 YSQILDFPRFREIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R + D E K+N AVFP QGGP + IAA AI K+ Sbjct: 237 GLILARA-----------------NADIEKKLNSAVFPGAQGGPLEHVIAAKAICFKEAL 279 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+KAY +QV+KNAQA+A + R +V+GGT NHL L L ++GK+ + Sbjct: 280 QPEFKAYQEQVVKNAQAMAEVFIARGFDVVSGGTKNHLFLLSLIKQDISGKDADAALGKA 339 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK + D S G+R GTPA+TTRG E + + +A ++ Sbjct: 340 FITVNKNSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELAGWI 385
>Q47MD6:GLYA_THEFY Serine hydroxymethyltransferase - Thermobifida fusca (strain YX)| Length = 423 Score = 308 bits (788), Expect = 8e-83 Identities = 183/431 (42%), Positives = 249/431 (57%), Gaps = 6/431 (1%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 Q LA+ DP+V A ++ E RQ +E+IASENF RAVL+A G+ LTNKY+EG+PG RYY Sbjct: 10 QSLAQLDPEVAAAVDAELARQRDTLEMIASENFAPRAVLEAQGTVLTNKYAEGYPGRRYY 69 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG +H+D IE+L RA FG + A NVQP+S AN AVY LL P D I+GL+ Sbjct: 70 GGCEHVDVIEQLAIDRAKALFGAEHA----NVQPHSGAQANTAVYFALLQPGDTILGLDL 125 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 GGH++HG +++ + +++Y V G IDYD++E A + PK++I G Sbjct: 126 AHGGHLTHGM------RINYSGKILNAVAYHVRESDGLIDYDEVEALAKEHQPKLIIAGW 179 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S+YPR+ DFAR R IAD+ GA+LM DMAH +GLVAA +P Y DVVT+TTHK L GP Sbjct: 180 SAYPRQLDFARFREIADQTGALLMVDMAHFAGLVAAGLHPNPVPYADVVTTTTHKTLGGP 239 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 RGG+I ++ + KIN AVFP +QGGP + IAA A+ LK Sbjct: 240 RGGLILAKE-------------------ELGKKINSAVFPGMQGGPLQHVIAAKAVALKV 280 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKC-----RLVTGGTDNHLVLWDLRTFGLTGKNF 1689 A+ E+ ++ + A+ LA L + R++TGGTD HLVL DL L GK Sbjct: 281 AASEEFAERQRRTLSGAKILAERLTQPDAAEAGIRVLTGGTDVHLVLVDLVNSELNGKEA 340 Query: 1690 EKVCELCHISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIA 1866 E I++N+ + D + G+RIGTPA+ TRG + DF +AD + A + Sbjct: 341 EDRLHEIGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDADFAEVADIIAEALKPG 400 Query: 1867 GSVLKQHGKVQ 1899 +VQ Sbjct: 401 FDAATLRSRVQ 411
>Q9RYB2:GLYA_DEIRA Serine hydroxymethyltransferase - Deinococcus radiodurans| Length = 408 Score = 308 bits (788), Expect = 8e-83 Identities = 174/412 (42%), Positives = 249/412 (60%), Gaps = 1/412 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +QP A D V L+ +E +RQ G+ELIASENF AV +A GS LTNKY+EG+PG R+ Sbjct: 5 DQPQAVRDDAVFDLIAQEAERQRTGLELIASENFTSAAVREAQGSVLTNKYAEGYPGKRW 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + +D +E+L R F + A NVQP+S +SANLAVY L+ P D ++G++ Sbjct: 65 YGGCEVVDQVEQLAIDRVKQLFNAEWA----NVQPHSGSSANLAVYNALIQPGDTVLGMD 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG K + + + ++ ++Y+++ +T ID +++ A + PK++I G Sbjct: 121 LSHGGHLTHG------NKANFSGMRYQMVAYQLDRETERIDMEEVRRLAHEHKPKMIIAG 174 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y R DFA R IAD+ GA+L D+AHI+GL+AA E + + VV STTHK LRG Sbjct: 175 ASAYSRVIDFAAFREIADEVGALLFADIAHIAGLIAAGEHPNALPHAHVVASTTHKTLRG 234 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGGII ND + +++ VFP QGGP + IAA A+ Sbjct: 235 PRGGIIL------------------ANDPEIAKQLDRTVFPGYQGGPLEHVIAAKAVAFG 276 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+K Y +Q++KNAQALA ++ R+V+GGTDNHL L DLR GL G ++ Sbjct: 277 EALRPEFKDYARQIIKNAQALAGEFQQKGYRVVSGGTDNHLFLLDLRPQGLNGTKATRLL 336 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 + HI+I+K+ + Y + GG+RIGTPA+TTRG E +AD + RA Sbjct: 337 DANHITISKSTLPYDTEKILHGGGIRIGTPAVTTRGMTEAHMTQVADLIDRA 388
>Q30P60:GLYA2_THIDN Serine hydroxymethyltransferase 2 - Thiomicrospira denitrificans| (strain ATCC 33889 / DSM 1351) Length = 420 Score = 308 bits (788), Expect = 8e-83 Identities = 178/429 (41%), Positives = 249/429 (58%), Gaps = 1/429 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 ++ L AD +V +++E E RQ +E+IASENF AV++A+GS TNKY+EG+P RY Sbjct: 6 SKSLEHADREVFSIIEGELKRQTAHLEMIASENFTSPAVMEAMGSVFTNKYAEGYPYKRY 65 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG ++ DA+E+L RA FG C NVQP+S + AN AVY LL D+++G++ Sbjct: 66 YGGCEYADAVEQLAIDRACEIFG----CKFANVQPHSGSQANAAVYAALLKAGDKLLGMD 121 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG K S + + S +Y V G +DYDK+ + A PKI++CG Sbjct: 122 LSHGGHLTHG------SKPSFSGQNYSSFTYGVEAD-GRMDYDKILEIAKAVQPKIIVCG 174 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y RE DF + R IAD GA L D+AH++GLVAA E SPF + VVT+TTHK LRG Sbjct: 175 ASAYAREIDFKKFREIADAVGAFLFADIAHVAGLVAADEHMSPFPHAHVVTTTTHKTLRG 234 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I +D + KIN A+FP +QGGP + IAA A+ K Sbjct: 235 PRGGMIM------------------TDDEEIAKKINSAIFPGIQGGPLVHVIAAKAVAFK 276 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 ++ P ++ Y +QV NA+ L L +R LV+GGTDNHLVL +GK+ + Sbjct: 277 EILDPSWREYAKQVKANAKVLEVVLTKRGYDLVSGGTDNHLVLVSFLNRDFSGKDADAAL 336 Query: 1702 ELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVL 1878 E I++NK + D S G+RIG+PA+T RG E +FE+IA+ + Sbjct: 337 ERAGITVNKNGVPNDTRSPFITSGIRIGSPALTARGMKEAEFELIANKICDVLDNINDT- 395 Query: 1879 KQHGKVQKE 1905 + H K+ KE Sbjct: 396 ELHVKINKE 404
>Q6LHN7:GLYA2_PHOPR Serine hydroxymethyltransferase 2 - Photobacterium profundum| (Photobacterium sp. (strain SS9)) Length = 431 Score = 308 bits (788), Expect = 8e-83 Identities = 186/435 (42%), Positives = 255/435 (58%), Gaps = 8/435 (1%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ D V+A +E E +RQ + IELIASEN V +AV+ A G+ LTNKY+EG+ G RYYGG Sbjct: 18 LAQVDGAVNAGIEAELNRQNQQIELIASENIVSKAVMQAQGTCLTNKYAEGYAGHRYYGG 77 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E++ RA F C VNVQP+S AN AV LL P D I+G+ + Sbjct: 78 CEHVDEVEKIAIARAKQLF----QCEYVNVQPHSGAQANGAVMLALLQPGDTILGMSLDA 133 Query: 991 GGHVSHGYYTP-SGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 GGH++HG SGK +F+++ Y VN T IDY+++ + A++ PK++I GGS Sbjct: 134 GGHLTHGARPALSGK-------WFDAVQYGVNKDTLEIDYNQVRELAIEHKPKMIIAGGS 186 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 + PR +FA+ R IAD+ GA LM DMAHI+GL+AA E SP + V+T+TTHK LRGPR Sbjct: 187 AIPRIINFAKFREIADEVGAFLMVDMAHIAGLIAAGEHPSPIPHAHVITTTTHKTLRGPR 246 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 GG+I N D KIN AVFP LQGGP + IA A+ + Sbjct: 247 GGMIL------------------TNLEDINKKINSAVFPGLQGGPLMHVIAGKAVAFGEA 288 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 P++K YI+ V+ NA+ LA L R C +VT GTD HL+L DLR GL G E E Sbjct: 289 LEPDFKIYIKNVISNAKVLAEVLQNRGCDIVTNGTDTHLMLVDLRPKGLKGNAAENALER 348 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL------IRATQIA 1866 I+ NK I + + G+R+GTPA T+RG D+F+ I +++ + A Sbjct: 349 AGITCNKNGIPFDTEKPMVTSGIRLGTPAGTSRGFGNDEFKQIGEWIGDVLDGLAANPED 408 Query: 1867 GSVLKQHGKVQKEFL 1911 S +++H K Q + L Sbjct: 409 NSEVEKHVKQQVQKL 423
>Q3KDV1:GLYA1_PSEPF Serine hydroxymethyltransferase 1 - Pseudomonas fluorescens (strain| PfO-1) Length = 412 Score = 308 bits (788), Expect = 8e-83 Identities = 174/406 (42%), Positives = 240/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L DP + L++RER+RQ +ELIASEN+V VL A GS LTNKY+EG+PG RYYGG Sbjct: 3 LQNFDPAIARLIDRERNRQETHLELIASENYVSEEVLQAQGSLLTNKYAEGYPGRRYYGG 62 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D IE L +RA FG C VNVQP+S + AN AV+ +L P DRI+G+ Sbjct: 63 CKVVDEIENLAIERARKLFG----CEYVNVQPHSGSQANQAVFLAVLEPGDRILGMSLAH 118 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + FF++ +Y + + +DYD++ED A + PK++I G S+ Sbjct: 119 GGHLTHG------ASVNFSGKFFQAFTYGLEKDSETLDYDQMEDLAREHRPKMIIAGASA 172 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF R R I D+ GA LM DMAH +GL+AA SP D +TSTTHK LRGPRG Sbjct: 173 YSRVIDFPRFRKICDEIGAYLMVDMAHYAGLIAAGVYPSPVGIADFITSTTHKTLRGPRG 232 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++ ++ +FP QGGP + IAA A+ + Sbjct: 233 GLILAKA-------------------EYAAVLDKTIFPVYQGGPLMHVIAAKAVAFNEAL 273 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 E+K Y Q+V+ NA+ +A L RR R+V+GGTD H+ L DLR +TGK+ E + E Sbjct: 274 GDEFKHYQQRVINNARTMADVLTRRGLRVVSGGTDCHMFLLDLRAMNITGKDAEALLESA 333 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+RIGTPA+TTRG E + +A+ + Sbjct: 334 HITLNKNAIPDDPQKPAITSGIRIGTPALTTRGFGEAECAEVANLI 379
>Q71WN9:GLYA_LISMF Serine hydroxymethyltransferase - Listeria monocytogenes serotype 4b| (strain F2365) Length = 413 Score = 307 bits (786), Expect = 1e-82 Identities = 175/453 (38%), Positives = 260/453 (57%), Gaps = 1/453 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + D +V ++ E RQ IELIASENFV V++A+GS LTNKY+EG+PG RYYGG Sbjct: 4 LQKQDKEVFDAIKLELGRQRANIELIASENFVSEQVMEAMGSVLTNKYAEGYPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D +E L RA FG + A NVQP+S AN+AVY +L P D ++G+ Sbjct: 64 CEFVDIVEDLARDRAKKLFGAEYA----NVQPHSGAQANMAVYHTVLEPGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + + Y V T IDYD + + A+ PK+++ G S+ Sbjct: 120 GGHLTHG------SPVNFSGVLYNFVEYGVREDTKEIDYDIVREAALKHKPKMIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR+ DFA+ R IAD+ GA LM DMAHI+GLVAA ++P Y D T+TTHK LRGPRG Sbjct: 174 YPRKIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPYADFTTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++E K+N ++FP +QGGP + IAA A+ + Sbjct: 234 GMILAKA-------------------EWEQKLNKSIFPGIQGGPLMHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+ AY +Q+++N++ LA L ++TGG+DNHL+L DL+ GLTGK EKV + Sbjct: 275 QPEFTAYCEQIIRNSKKLAETLQANDVAVLTGGSDNHLLLIDLKPLGLTGKAAEKVLDEV 334 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I++NK I + G+R+G A+TTRG F+ +A +++ Sbjct: 335 GITVNKNTIPFETESPFVTSGIRVGVAAVTTRG-----FDEVA-------------IEKV 376 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 G + E L LEN + + ++ +V +++ + Sbjct: 377 GVLISEVLHNLENEEVLADVKARVATLTNEYPL 409
>Q8XJ32:GLYA_CLOPE Serine hydroxymethyltransferase - Clostridium perfringens| Length = 410 Score = 306 bits (785), Expect = 2e-82 Identities = 170/406 (41%), Positives = 245/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L D + L+++E++RQ IELIASENFV +AV++A+GS+LTNKY+EG+P RYYGG Sbjct: 6 LEREDEQIAHLVQKEKERQENSIELIASENFVSKAVMEAMGSYLTNKYAEGYPSKRYYGG 65 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +D +E L +R FG + A NVQP+S + AN+AVY +L P D ++G++ Sbjct: 66 CHVVDEVEDLARERVKKLFGAEHA----NVQPHSGSQANMAVYFSILEPGDTVLGMDLSH 121 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + F +SY V+ +T I+Y+ + + A+ PK+++ G S+ Sbjct: 122 GGHLTHG------SSVNFSGRLFNFVSYGVDKETETINYETVRELALKHKPKLIVAGASA 175 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF +R IAD+ GA LM D+AHI+GLVA SP Y D VTSTTHK LRGPRG Sbjct: 176 YSRIIDFKTLREIADEVGAYLMVDIAHIAGLVATGLHPSPVPYADFVTSTTHKTLRGPRG 235 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ++ F ++ +FP +QGGP + IAA A+ K+ Sbjct: 236 GLILCKE-------------------KFAKVLDKNIFPGIQGGPLMHIIAAKAVCFKEAL 276 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P +K Y++QV+KNA LA AL +LV+ GTDNHL+L DL +TGK+ E + + Sbjct: 277 EPSFKTYMEQVVKNAHVLAEALEAYGFKLVSNGTDNHLILVDLTNKDITGKDAEILLDSI 336 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK + + S GVRIGTPA+TTRG E++ + IA + Sbjct: 337 GITLNKNTVPNETRSPFVTSGVRIGTPAITTRGFKEEEMKEIASII 382
>Q6MLK1:GLYA_BDEBA Serine hydroxymethyltransferase - Bdellovibrio bacteriovorus| Length = 415 Score = 306 bits (785), Expect = 2e-82 Identities = 172/428 (40%), Positives = 253/428 (59%), Gaps = 4/428 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DP++ A + +E +RQ G+E+IASEN+ +AV++A GS LTNKY+EG+PG RYYGG Sbjct: 8 LAQVDPEILAAINKESERQQFGLEMIASENYTSKAVMEAQGSILTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 ++D +E L +RA FG+ A NVQP+S + AN+ VY + I+G++ Sbjct: 68 CVNVDTVESLAIERAKKLFGVQYA----NVQPHSGSQANMGVYLAACKAGETILGMDLSH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + F++ SYK++P+TG ++YD + A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGMLFKAASYKLDPETGRLNYDTIRATAKEVQPKLIIAGYSA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DFA+ + IAD+ GA L+ DMAH +GLVA SP Y D +T+TTHK LRGPRG Sbjct: 178 YPRTLDFAKFKEIADEVGAQLLVDMAHFAGLVATGHHPSPVPYADYITTTTHKTLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I N + +N +FP +QGGP + IA A+ + Sbjct: 238 GMIL------------------TNSEEKAKTMNSRIFPGIQGGPLEHVIAGKAVAFGEAL 279 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y +V+ NA+ LA LL +LVTGGTDNHL+L DL +TGK E + Sbjct: 280 KPEFKDYSGKVVSNAKVLAEELLSAGFKLVTGGTDNHLILVDLSDREITGKLAENSLDEA 339 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL---IRATQIAGSVL 1878 I++NK + + S GVRIGTPA+TTRG + + IA ++ + + AG Sbjct: 340 GITVNKNTVPNEKRSPFVTSGVRIGTPALTTRGMGPAEMKQIAKWIGQVLNNAEDAGVKN 399 Query: 1879 KQHGKVQK 1902 + H +V++ Sbjct: 400 RVHEEVKE 407
>Q87WC1:GLYA2_PSESM Serine hydroxymethyltransferase 2 - Pseudomonas syringae pv. tomato| Length = 417 Score = 306 bits (784), Expect = 2e-82 Identities = 176/406 (43%), Positives = 244/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D D+ A ME+E RQ IELIASEN+ AV++A GS LTNKY+EG+PG RYYGG Sbjct: 8 IAKYDADLFAAMEQEALRQEEHIELIASENYTSPAVMEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP++ + AN AVY LL D I+G+ Sbjct: 68 CEYVDVVEQLAIDRAKELFGADYA----NVQPHAGSQANSAVYLALLQGGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG VS + + ++ Y ++ G IDYD++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG------ASVSSSGKLYNAVQYGIDGN-GMIDYDEVERLAVEHKPKMIVAGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + DF R R IADK GA L DMAH++GLVAA +P + DVVT+TTHK LRGPRG Sbjct: 177 YSQILDFPRFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R + D E K+N AVFP QGGP + IAA AI K+ Sbjct: 237 GLILARA-----------------NADIEKKLNSAVFPGSQGGPLEHVIAAKAICFKEAL 279 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV+KNA+A+A + R +V+GGT+NHL L L ++GK+ + Sbjct: 280 QPEFKTYQQQVVKNAKAMAGVFIERGFDVVSGGTENHLFLLSLIKQDISGKDADAALGRA 339 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK + D S G+R GTPA+TTRG E + + +A ++ Sbjct: 340 FITVNKNSVPNDPRSPFVTSGLRFGTPAVTTRGFKETECKELAGWI 385
>Q63MV1:GLYA2_BURPS Serine hydroxymethyltransferase 2 - Burkholderia pseudomallei| (Pseudomonas pseudomallei) Length = 424 Score = 306 bits (783), Expect = 3e-82 Identities = 180/410 (43%), Positives = 233/410 (56%), Gaps = 1/410 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +Q LAE D V + +E +RQ +ELIASEN V RAVLDA GS LTNKY+EG+PG RY Sbjct: 9 SQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRY 68 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + D +E L +R F A NVQP+S AN AV L P D ++G+ Sbjct: 69 YGGCEFADEVEALAIERVKRLFNAGHA----NVQPHSGAQANGAVMLALAKPGDTVLGMS 124 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 +GGH++HG K + + +F +L Y V+ T IDYD++E A P ++I G Sbjct: 125 LDAGGHLTHG------AKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHKPSLIIAG 178 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR+ DFAR R IAD GA LM DMAHI+G++AA +P ++ VVTSTTHK LRG Sbjct: 179 FSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRG 238 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG + ND + KIN AVFP LQGGP + IA A+ Sbjct: 239 PRGGFVL------------------TNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFG 280 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + T ++K YI +V+ NAQAL L LVTGGTDNHL+L DLR GL G E+ Sbjct: 281 EALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQAL 340 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 E I+ NK I + G+R+GTPA TTRG +F + ++ Sbjct: 341 ERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLIL 390
>Q3JGP5:GLYA2_BURP1 Serine hydroxymethyltransferase 2 - Burkholderia pseudomallei (strain| 1710b) Length = 424 Score = 306 bits (783), Expect = 3e-82 Identities = 180/410 (43%), Positives = 233/410 (56%), Gaps = 1/410 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +Q LAE D V + +E +RQ +ELIASEN V RAVLDA GS LTNKY+EG+PG RY Sbjct: 9 SQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRY 68 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + D +E L +R F A NVQP+S AN AV L P D ++G+ Sbjct: 69 YGGCEFADEVEALAIERVKRLFNAGHA----NVQPHSGAQANGAVMLALAKPGDTVLGMS 124 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 +GGH++HG K + + +F +L Y V+ T IDYD++E A P ++I G Sbjct: 125 LDAGGHLTHG------AKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHKPSLIIAG 178 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR+ DFAR R IAD GA LM DMAHI+G++AA +P ++ VVTSTTHK LRG Sbjct: 179 FSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRG 238 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG + ND + KIN AVFP LQGGP + IA A+ Sbjct: 239 PRGGFVL------------------TNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFG 280 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + T ++K YI +V+ NAQAL L LVTGGTDNHL+L DLR GL G E+ Sbjct: 281 EALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQAL 340 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 E I+ NK I + G+R+GTPA TTRG +F + ++ Sbjct: 341 ERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLIL 390
>Q983B6:GLYA1_RHILO Serine hydroxymethyltransferase 1 - Rhizobium loti (Mesorhizobium| loti) Length = 437 Score = 306 bits (783), Expect = 3e-82 Identities = 180/406 (44%), Positives = 233/406 (57%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L +ADP++ + E RQ IELIASEN V RAVL+A GS +TNKY+EG+PG RYYGG Sbjct: 19 LEDADPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSIMTNKYAEGYPGKRYYGG 78 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 Q +D E L +RA FG C NVQP S + N AV+ LL P D MGL+ S Sbjct: 79 CQFVDVAEELAIERAKKLFG----CNFANVQPNSGSQMNQAVFLALLQPGDTFMGLDLNS 134 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F+ +SY V + +D D +E A + PK+++ GG++ Sbjct: 135 GGHLTHG------SPVNMSGKWFKVVSYGVRKEDHLLDMDAIEKTAHETKPKLILAGGTA 188 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R WD+ R R IAD GA LM DMAHI+GLVA SP + VVT+TTHK+LRGPRG Sbjct: 189 YSRIWDWKRFREIADAVGAYLMVDMAHIAGLVAGGVHPSPLPHAHVVTTTTHKSLRGPRG 248 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ND D K+N AVFP LQGGP + IAA A+ + Sbjct: 249 GMILC------------------NDEDIAKKMNSAVFPGLQGGPLMHVIAAKAVAFGEAL 290 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P +K Y + V NA+ALAS+L +V+GGTDNHL+L DLR TGK E Sbjct: 291 KPSFKVYAESVAANAKALASSLKETGLDIVSGGTDNHLMLVDLRPKNATGKRAEAALGRA 350 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK I + GVR+GTPA TTRG + +F I + Sbjct: 351 NITCNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFGQAEFREIGKLI 396
>Q8PPE3:GLYA_XANAC Serine hydroxymethyltransferase - Xanthomonas axonopodis pv. citri| Length = 417 Score = 305 bits (782), Expect = 4e-82 Identities = 176/402 (43%), Positives = 245/402 (60%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP++ + E RQ +ELIASEN+ V++A GS LTNKY+EG+PG RYYGG + + Sbjct: 12 DPELAKAIAAEAGRQEDHVELIASENYCSPLVMEAQGSQLTNKYAEGYPGKRYYGGCEFV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E+L +R FG D A NVQP+S + AN AVY LL P D I+G+ GGH+ Sbjct: 72 DIAEQLAIERIKQVFGADYA----NVQPHSGSQANQAVYLALLQPGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KV+ + F ++ Y VN Q G IDYD+++ A + PK+++ G S+Y ++ Sbjct: 128 THG------AKVNVSGKLFNAVQYGVNEQ-GLIDYDEVQRLATEHKPKMVVAGFSAYSQK 180 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 D+AR R IAD GA L DMAHI+GLVAA SP ++ VVTSTTHK LRGPRGGII Sbjct: 181 IDWARFRAIADSVGAYLFVDMAHIAGLVAAGVYPSPMEHAHVVTSTTHKTLRGPRGGIIV 240 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 +G S + + K+ VFP +QGGP + IAA A+ K+ P + Sbjct: 241 --------AKGAS--------EELQKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y QQV+KNAQA+A+ L+ R ++V+GGT+NHL+L D+ ++GK+ E HI++ Sbjct: 285 KTYQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + D S G+R+GTPA+TTRG E D +A+++ Sbjct: 345 NKNSVPNDPRSPFVTSGLRLGTPAITTRGYQEQDSIDLANWI 386
>Q8Y4B2:GLYA_LISMO Serine hydroxymethyltransferase - Listeria monocytogenes| Length = 413 Score = 305 bits (782), Expect = 4e-82 Identities = 174/453 (38%), Positives = 259/453 (57%), Gaps = 1/453 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + D +V ++ E RQ IELIASENFV V++A+GS LTNKY+EG+PG RYYGG Sbjct: 4 LQKQDKEVFDAIKLELGRQRANIELIASENFVSEQVMEAMGSVLTNKYAEGYPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D +E L RA FG + A NVQP+S AN+AVY +L P D ++G+ Sbjct: 64 CEFVDIVEDLARDRAKKLFGAEYA----NVQPHSGAQANMAVYHTVLEPGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + + Y V T IDYD + + A+ PK+++ G S+ Sbjct: 120 GGHLTHG------SPVNFSGVLYNFVEYGVREDTKEIDYDIVREAALKHKPKMIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR+ DFA+ R IAD+ GA LM DMAHI+GLVAA ++P Y D T+TTHK LRGPRG Sbjct: 174 YPRKIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPYADFTTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++E K+N ++FP +QGGP + IAA A+ + Sbjct: 234 GMILAKA-------------------EWEQKLNKSIFPGIQGGPLMHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+ Y +Q+++N++ LA L ++TGG+DNHL+L DL+ GLTGK EKV + Sbjct: 275 QPEFTTYCEQIIRNSKKLAETLQANDVAVLTGGSDNHLLLIDLKPLGLTGKAAEKVLDEV 334 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I++NK I + G+R+G A+TTRG F+ +A +++ Sbjct: 335 GITVNKNTIPFETESPFVTSGIRVGVAAVTTRG-----FDEVA-------------IEKV 376 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 G + E L LEN + + ++ +V +++ + Sbjct: 377 GVLISEVLHNLENEEVLADVKARVATLTNEYPL 409
>Q5FNK4:GLYA_GLUOX Serine hydroxymethyltransferase - Gluconobacter oxydans| (Gluconobacter suboxydans) Length = 434 Score = 305 bits (782), Expect = 4e-82 Identities = 180/415 (43%), Positives = 238/415 (57%), Gaps = 1/415 (0%) Frame = +1 Query: 592 ARRRAVRAWGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNK 771 A + + + + PL E D +V ++ E RQ GIELIASEN AV++A GS LTNK Sbjct: 5 ASQSTLNRFFHAPLKEVDAEVATILNEELTRQQDGIELIASENMASFAVMEAQGSVLTNK 64 Query: 772 YSEGHPGARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLL 951 Y+EG PG RYYGG +D +E L R FG + A NVQP+S +AN A + L Sbjct: 65 YAEGLPGKRYYGGCVDVDRVENLAIDRLKKIFGAEFA----NVQPHSGANANQAAFMALA 120 Query: 952 LPNDRIMGLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAM 1131 P D ++GL +GGH++HG + SG +F S+ Y V + G IDYD++E A Sbjct: 121 KPGDTVLGLSLAAGGHLTHG----AAPNYSGK--WFNSVQYGVRAEDGLIDYDQMEALAR 174 Query: 1132 DFHPKILICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVV 1311 + PKI++ G S+YPR DFAR R IAD+ GA LM DMAH +GLVAA +P D+ Sbjct: 175 EHKPKIIVAGSSAYPRVIDFARFRKIADEVGAYLMVDMAHFAGLVAAGLYPNPVPMADIT 234 Query: 1312 TSTTHKNLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNN 1491 TSTTHK LRGPRGGII N+ D K+N AVFP LQGGP + Sbjct: 235 TSTTHKTLRGPRGGIIL------------------TNNPDLAKKVNSAVFPGLQGGPLMH 276 Query: 1492 HIAALAITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFG 1671 IA A+ + + E+KAY ++V+ NA+ALA L R +VTGGTD+HL+L DLR Sbjct: 277 VIAGKAVAFGEALSDEFKAYQKRVLANARALADELQNRGFDIVTGGTDSHLILVDLRPKK 336 Query: 1672 LTGKNFEKVCELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVI 1833 +TGK E + E I+ NK I + G+R+G+PA T RG E +F + Sbjct: 337 VTGKLAEAILERAGITANKNAIPFDPEKPFVTSGIRLGSPAATARGFGEAEFREV 391
>Q2T437:GLYA2_BURTA Serine hydroxymethyltransferase 2 - Burkholderia thailandensis| (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) Length = 424 Score = 305 bits (782), Expect = 4e-82 Identities = 180/411 (43%), Positives = 236/411 (57%), Gaps = 2/411 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +Q LAE D V + +E +RQ +ELIASEN V RAVLDA GS LTNKY+EG+PG RY Sbjct: 9 SQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRY 68 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + D +E L R F A NVQP+S AN AV L P D ++G+ Sbjct: 69 YGGCEFADEVEALAIDRVKQIFNAGHA----NVQPHSGAQANGAVMLALAKPGDTVLGMS 124 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 +GGH++HG K + + +F ++ Y V+ T IDYD++E+ A P ++I G Sbjct: 125 LDAGGHLTHG------AKPALSGKWFNAVQYGVSRDTMLIDYDQVEELAQQHKPSLIIAG 178 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR+ DFAR R IAD GA LM DMAHI+G++AA +P ++ VVTSTTHK LRG Sbjct: 179 FSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRG 238 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG + ND + KIN AVFP LQGGP + IA A+ Sbjct: 239 PRGGFVL------------------TNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFG 280 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + T ++K YI +V+ NAQAL L LVTGGTDNHL+L DLR GL G E+ Sbjct: 281 EALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQAL 340 Query: 1702 ELCHISINKT--PIYGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 E I+ NK P + +I+ G+R+GTPA TTRG +F + ++ Sbjct: 341 ERSGITCNKNGIPFDAEKPTIT-SGIRLGTPAGTTRGFGAAEFREVGRLIL 390
>Q48DU7:GLYA1_PSE14 Serine hydroxymethyltransferase 1 - Pseudomonas syringae pv.| phaseolicola (strain 1448A / Race 6) Length = 417 Score = 305 bits (781), Expect = 5e-82 Identities = 175/406 (43%), Positives = 244/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D D+ A ME+E RQ IELIASEN+ AV++A GS LTNKY+EG+PG RYYGG Sbjct: 8 IAKYDADLFAAMEQEALRQEEHIELIASENYTSPAVMEAQGSALTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D IE+L RA FG D A NVQP++ + AN AVY LL D I+G+ Sbjct: 68 CEYVDVIEQLAIDRAKELFGADYA----NVQPHAGSQANSAVYLALLQGGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG VS + + ++ Y ++ G IDYD++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG------ASVSSSGKLYNAVQYGIDAN-GMIDYDEVERLAVEHKPKMIVAGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + DF R R IADK GA L DMAH++GLVAA +P + DVVT+TTHK LRGPRG Sbjct: 177 YSQILDFPRFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R + + E K+N AVFP QGGP + IAA A+ K+ Sbjct: 237 GLILARA-----------------NAEIEKKLNSAVFPGSQGGPLEHVIAAKAVCFKEAL 279 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV+KNA+A+A + R +V+GGT+NHL L L ++GK+ + Sbjct: 280 QPEFKTYQQQVVKNAKAMAGVFIERGFDVVSGGTENHLFLLSLIKQDISGKDADAALGRA 339 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK + D S G+R GTPA+TTRG E + + +A ++ Sbjct: 340 FITVNKNSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELAGWI 385
>Q927V4:GLYA_LISIN Serine hydroxymethyltransferase - Listeria innocua| Length = 413 Score = 305 bits (780), Expect = 7e-82 Identities = 174/453 (38%), Positives = 260/453 (57%), Gaps = 1/453 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + D +V ++ E RQ IELIASENFV V++A+GS LTNKY+EG+PG RYYGG Sbjct: 4 LQKQDKEVFDAIKLELGRQRANIELIASENFVSEQVMEAMGSVLTNKYAEGYPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D +E L RA FG + A NVQP+S AN+AVY +L P D ++G+ Sbjct: 64 CEFVDIVEDLARDRAKKLFGAEYA----NVQPHSGAQANMAVYHTVLEPGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + + Y V T IDY+ + + A+ PK+++ G S+ Sbjct: 120 GGHLTHG------SPVNFSGVLYNFVEYGVREDTKEIDYEIVREAALKHKPKMIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR+ DFA+ R IAD+ GA LM DMAHI+GLVAA ++P Y D T+TTHK LRGPRG Sbjct: 174 YPRKIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPYADFTTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++E K+N ++FP +QGGP + IAA A+ + Sbjct: 234 GMILAKA-------------------EWEQKLNKSIFPGIQGGPLMHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+ AY +Q+++N++ LA L ++TGG+DNHL+L DL+ GLTGK EKV + Sbjct: 275 QPEFTAYCEQIIRNSKKLAETLQANDVAVLTGGSDNHLLLIDLKPLGLTGKAAEKVLDEV 334 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I++NK I + G+R+G A+TTRG F+ +A +++ Sbjct: 335 GITVNKNTIPFETESPFVTSGIRVGVAAVTTRG-----FDEVA-------------IEKV 376 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 G + E L LEN + + ++ +V +++ + Sbjct: 377 GVLISEVLHNLENEEVLADVKARVANLTNEYPL 409
>Q7NYI8:GLYA_CHRVO Serine hydroxymethyltransferase - Chromobacterium violaceum| Length = 415 Score = 305 bits (780), Expect = 7e-82 Identities = 179/409 (43%), Positives = 242/409 (59%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +Q +A+ DP++ A + E RQ IELIASEN+ AV++A GS LTNKY+EG+PG R+ Sbjct: 5 DQTIAKFDPELAAAIAAECQRQEDHIELIASENYTSPAVMEAQGSQLTNKYAEGYPGKRF 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +H+D +E+L R FG + A NVQP+S + AN AVY +L P D +MG+ Sbjct: 65 YGGCEHVDVVEQLAIDRVKQLFGAEYA----NVQPHSGSQANQAVYFSILKPGDTVMGMN 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG S +SG F ++Y +N + IDYD +E AM+ PK++I G Sbjct: 121 LGHGGHLTHG----SPANLSGK--MFNIVAYGLNDKEE-IDYDDMERVAMETKPKLIIGG 173 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y +DF RM IA K GA M DMAH +GLVAA +P + D VTSTTHK LRG Sbjct: 174 ASAYALRFDFERMGQIAKKVGAYFMVDMAHYAGLVAAGLYPNPVPHADFVTSTTHKTLRG 233 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGGII + +FE IN VFP+LQGGP + IAA A+ K Sbjct: 234 PRGGIILAKA-------------------EFEKSINSNVFPTLQGGPLEHVIAAKAVAFK 274 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + P +K Y QQV+KNA +A L R R+V+G T++H+ L DLR GLTGK + + Sbjct: 275 EALQPAFKEYQQQVLKNAAIMAKTLAERGLRIVSGRTESHVFLVDLRAKGLTGKQADALL 334 Query: 1702 ELCHISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+RIG+PA+TTRG E + +A+ + Sbjct: 335 GRAHITVNKNAIPNDPETPFVTSGIRIGSPAITTRGFKEAEAIEVANMV 383
>Q46RR4:GLYA2_RALEJ Serine hydroxymethyltransferase 2 - Ralstonia eutropha (strain| JMP134) (Alcaligenes eutrophus) Length = 424 Score = 305 bits (780), Expect = 7e-82 Identities = 179/410 (43%), Positives = 235/410 (57%), Gaps = 1/410 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +QPLAE D V + +E +RQ +ELIASEN V RAVL+A GS LTNKY+EG+PG RY Sbjct: 9 SQPLAERDALVRGALSKELERQQSQVELIASENIVSRAVLEAQGSVLTNKYAEGYPGKRY 68 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + D +E L +R F A NVQP+S AN +V L P D ++G+ Sbjct: 69 YGGCKFADEVESLAIERVKQLFNAGFA----NVQPHSGAQANGSVMLALTKPGDTVLGMS 124 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 +GGH++HG K + + +F ++ Y VN ++ IDYD++E A + P ++I G Sbjct: 125 LDAGGHLTHG------AKPALSGKWFNAVQYGVNRESMLIDYDQVEALAKEHKPSLIIAG 178 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR+ DFAR R IAD GA LM DMAHI+G++AA +P DY VVTSTTHK LRG Sbjct: 179 FSAYPRQLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHSNPVDYAHVVTSTTHKTLRG 238 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG + N + KIN AVFP LQGGP + IAA A+ Sbjct: 239 PRGGFVL------------------TNHEEIAKKINSAVFPGLQGGPLMHVIAAKAVAFG 280 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + T +++ YI V+ NA+AL L LVTGGTDNHL+L DLR GL G E+ Sbjct: 281 EAMTSDFRTYIDNVLANAKALGEVLKEGGVDLVTGGTDNHLLLVDLRPKGLKGTQVEQAL 340 Query: 1702 ELCHISINKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 E I+ NK I D + G+R+G PA TTRG +F I ++ Sbjct: 341 ERAGITCNKNGIPFDTEKPTITSGIRLGAPAATTRGFGVAEFREIGRLIL 390
>Q62DI5:GLYA2_BURMA Serine hydroxymethyltransferase 2 - Burkholderia mallei (Pseudomonas| mallei) Length = 424 Score = 305 bits (780), Expect = 7e-82 Identities = 179/410 (43%), Positives = 232/410 (56%), Gaps = 1/410 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +Q LAE D V + +E +RQ +ELIASEN V RAVLDA GS LTNKY+EG+PG RY Sbjct: 9 SQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRY 68 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + D +E L +R F A NVQP+S AN AV L P D ++G+ Sbjct: 69 YGGCEFADEVEALAIERVKRLFNAGHA----NVQPHSGAQANGAVMLALAKPGDTVLGMS 124 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 +GGH++HG K + + +F +L Y V+ T +DYD++E A P ++I G Sbjct: 125 LDAGGHLTHG------AKPALSGKWFNALQYGVSRDTMLLDYDQVEALAQQHKPSLIIAG 178 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR+ DFAR R IAD GA LM DMAHI+G++AA +P ++ VVTSTTHK LRG Sbjct: 179 FSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRG 238 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG + ND + KIN AVFP LQGGP + IA A+ Sbjct: 239 PRGGFVL------------------TNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFG 280 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + T ++K YI V+ NAQAL L LVTGGTDNHL+L DLR GL G E+ Sbjct: 281 EALTDDFKTYIDHVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQAL 340 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 E I+ NK I + G+R+GTPA TTRG +F + ++ Sbjct: 341 ERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLIL 390
>Q4ZNH2:GLYA1_PSEU2 Serine hydroxymethyltransferase 1 - Pseudomonas syringae pv. syringae| (strain B728a) Length = 417 Score = 305 bits (780), Expect = 7e-82 Identities = 175/406 (43%), Positives = 244/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D D+ A ME+E RQ IELIASEN+ AV++A GS LTNKY+EG+PG RYYGG Sbjct: 8 IAKYDADLFAAMEQEALRQEEHIELIASENYTSPAVMEAQGSALTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D IE+L RA FG D A NVQP++ + AN AVY LL D I+G+ Sbjct: 68 CEYVDIIEQLAIDRAKELFGADYA----NVQPHAGSQANSAVYLALLQGGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG VS + + ++ Y ++ G IDYD++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG------ASVSSSGKLYNAVQYGIDAN-GMIDYDEVERLAVEHKPKMIVAGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + DF R R IADK GA L DMAH++GLVAA +P + DVVT+TTHK LRGPRG Sbjct: 177 YSQILDFPRFRAIADKVGAYLFVDMAHVAGLVAAGVYPNPVPFADVVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R + + E K+N AVFP QGGP + IAA A+ K+ Sbjct: 237 GLILARA-----------------NAEIEKKLNSAVFPGSQGGPLEHVIAAKAVCFKEAL 279 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV+KNA+A+A + R +V+GGT+NHL L L ++GK+ + Sbjct: 280 QPEFKTYQQQVVKNAKAMAGVFIERGFDVVSGGTENHLFLLSLIKQDISGKDADAALGRA 339 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK + D S G+R GTPA+TTRG E + + +A ++ Sbjct: 340 FITVNKNSVPNDPRSPFVTSGLRFGTPAVTTRGFKEAECKELAGWI 385
>Q39A26:GLYA1_BURS3 Serine hydroxymethyltransferase 1 - Burkholderia sp. (strain 383)| (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) Length = 424 Score = 305 bits (780), Expect = 7e-82 Identities = 181/410 (44%), Positives = 234/410 (57%), Gaps = 1/410 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 +QPLAE D V + + +E +RQ +ELIASEN V RAVL+A GS LTNKY+EG+PG RY Sbjct: 9 SQPLAERDAPVRSAILKELERQQSQVELIASENIVSRAVLEAQGSVLTNKYAEGYPGKRY 68 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG + D +E L R F A NVQP+S AN +V L P D ++G+ Sbjct: 69 YGGCEFADEVEALAIDRVKQIFNAGYA----NVQPHSGAQANGSVMLALAKPGDTVLGMS 124 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 +GGH++HG K + + +F ++ Y VN T IDYD++E A + P ++I G Sbjct: 125 LDAGGHLTHG------AKPALSGKWFNAVQYGVNRDTMLIDYDQVEALAHEHKPNLIIAG 178 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+YPR DFAR R IAD GA LM DMAHI+G++AA +P ++ VVTSTTHK LRG Sbjct: 179 FSAYPRALDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRG 238 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG + ND D KIN AVFP LQGGP + IA A+ Sbjct: 239 PRGGFVL------------------TNDEDIAKKINSAVFPGLQGGPLMHVIAGKAVAFG 280 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 +V ++K YI V+ NAQAL L LVTGGTDNHL+L DLR GL G E+ Sbjct: 281 EVLQADFKTYIDNVLANAQALGEVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAPVEQAL 340 Query: 1702 ELCHISINKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 E I+ NK I D + G+R+GTPA TTRG +F + ++ Sbjct: 341 ERAGITCNKNGIPFDTEKPTVTSGIRLGTPAGTTRGFGVAEFREVGRLIL 390
>Q3B2I7:GLYA_PELLD Serine hydroxymethyltransferase - Pelodictyon luteolum (strain DSM| 273) (Chlorobium luteolum (strain DSM 273)) Length = 440 Score = 304 bits (779), Expect = 9e-82 Identities = 182/434 (41%), Positives = 249/434 (57%), Gaps = 8/434 (1%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D +V + E RQ+ +ELIASENF RAV+ A GS +TNKY+EG+PG RYYGG + + Sbjct: 10 DREVFDAIAGETVRQMETLELIASENFTSRAVMQACGSVMTNKYAEGYPGKRYYGGCEFV 69 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E L +RA FG C VNVQP+S +SAN+AV +L P DRIMGL+ GGH+ Sbjct: 70 DIAEDLARERARKLFG----CEYVNVQPHSGSSANMAVLFSVLKPGDRIMGLDLSHGGHL 125 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG V+ + F++ SY V+ +TG ID +K+E+ A+DF P+++ICG S+Y + Sbjct: 126 THG------SSVNFSGQMFDARSYGVDRETGIIDMNKVEEMALDFKPRLIICGASAYSQG 179 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 +DF R IADK GA LM D+AH +GL+AA P +C VT+TTHK LRGPRGG+I Sbjct: 180 FDFKAFREIADKVGAFLMADIAHPAGLIAAGLLTDPMPHCHFVTTTTHKTLRGPRGGMIM 239 Query: 1363 FRK------GKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 K G ++ + G + D E V P +QGGP + IA A+ + Sbjct: 240 MGKDFENPMGITIKTKNGPRVKMMSEVMDAE------VMPGIQGGPLMHIIAGKAVAFGE 293 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 PE++ Y QV KNA ++A +V+GGT NHL+L DLR + GK E + Sbjct: 294 ALRPEFREYAVQVRKNAASMAERFTSLGYNIVSGGTKNHLMLLDLRNKDVNGKVAENLLH 353 Query: 1705 LCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA-TQIAGSVL 1878 I++NK + + D G+RIGT AMTTRG E D +IA+ + R T A S + Sbjct: 354 DAGITVNKNMVPFDDKSPFVTSGIRIGTAAMTTRGMKEADATLIAELIDRVITGAAESTI 413 Query: 1879 KQHGKVQKEFLRGL 1920 K K +R L Sbjct: 414 AATCKDVKAEIRSL 427
>P56990:GLYA_NEIMB Serine hydroxymethyltransferase - Neisseria meningitidis serogroup B| Length = 416 Score = 304 bits (779), Expect = 9e-82 Identities = 173/406 (42%), Positives = 245/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DPD+ A + +E RQ +ELIASEN+V AV+DA GS LTNKY+EG+PG RYYGG Sbjct: 8 LAQYDPDLAAAIAQEDQRQQDHVELIASENYVSCAVMDAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG A NVQP+S + AN AVY +L P D I+G+ Sbjct: 68 CEYVDIVEQLAIDRVKELFGAAYA----NVQPHSGSQANQAVYASVLKPGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG + +SG + +++Y ++ + +DY ++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG----ASVNISGK--LYNAVTYGLD-ENEVLDYAEVERLALEHKPKMIVAGASA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + D+A+ R IADK GA L DMAH +GLVA E +P +CD VT+TTHK LRGPRG Sbjct: 177 YALQIDWAKFREIADKVGAYLFVDMAHYAGLVAGGEYPNPVPFCDFVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D E +N ++FPSLQGGP + IAA A+ K+ Sbjct: 237 GVILCR------------------DNTHEKALNSSIFPSLQGGPLMHVIAAKAVAFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y +QV NA A+A L++R R+V+G T++H+ L DL+ +TGK E Sbjct: 279 QPEFKQYAKQVKINAAAMAEELVKRGLRIVSGRTESHVFLVDLQPMKITGKAAEAALGKA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+RIG+ AMTTRG E D V+A+ + Sbjct: 339 HITVNKNAIPNDPEKPFVTSGIRIGSAAMTTRGFNEADARVLANLV 384
>Q7MEH7:GLYA2_VIBVY Serine hydroxymethyltransferase 2 - Vibrio vulnificus (strain YJ016)| Length = 431 Score = 304 bits (779), Expect = 9e-82 Identities = 188/455 (41%), Positives = 256/455 (56%), Gaps = 3/455 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L+ D V A ++ E RQ IELIASEN V +AV+ A G+ LTNKY+EG+PG RYYGG Sbjct: 18 LSATDDAVFAGIQAEFTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGG 77 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E + +RA F C NVQP+S AN AV LL P D IMG+ + Sbjct: 78 CEHVDTVEAIAIERAKKLFN----CEYANVQPHSGAQANGAVKLALLQPGDTIMGMSLDA 133 Query: 991 GGHVSHGYYTP-SGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 GGH++HG SGK +F ++ Y V+ +T I+YD + A++ PK++I GGS Sbjct: 134 GGHLTHGARPALSGK-------WFNAVQYGVDKETLEINYDDVRALAVEHKPKMIIAGGS 186 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 + PR DFA+ R IAD+ GA+LM DMAHI+GL+A SP + VVT+TTHK LRGPR Sbjct: 187 AIPRVIDFAKFREIADEVGAILMVDMAHIAGLIATGAHPSPLPHAHVVTTTTHKTLRGPR 246 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 GG+I N + KIN AVFP LQGGP + IAA A+ + Sbjct: 247 GGMIL------------------TNHEEIIKKINSAVFPGLQGGPLMHVIAAKAVAFGEA 288 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 PE+K YI V+ NA+ LA L R C +VTGGTD HL+L DLR GL G E+ E Sbjct: 289 LGPEFKTYIDSVINNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNKAEEALER 348 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQ 1884 I+ NK I + + GVR+GTPA T+RG ++F++I ++ Sbjct: 349 AGITCNKNGIPFDTEKPMITSGVRLGTPAGTSRGFGAEEFKLIGHWI------------- 395 Query: 1885 HGKVQKEFLRGLENNKDIIE-LGNQVEAFASQFAM 1986 G V + E N ++ + + +V+A S+F + Sbjct: 396 -GDVLDGLVENPEGNAEVEQRVRKEVKALCSRFPL 429
>Q3BXI8:GLYA_XANC5 Serine hydroxymethyltransferase - Xanthomonas campestris pv.| vesicatoria (strain 85-10) Length = 417 Score = 304 bits (778), Expect = 1e-81 Identities = 176/402 (43%), Positives = 244/402 (60%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP++ + E RQ +ELIASEN+ V++A GS LTNKY+EG+PG RYYGG + + Sbjct: 12 DPELAKAIAAEAGRQEDHVELIASENYCSPLVMEAQGSQLTNKYAEGYPGKRYYGGCEFV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E+L R FG D A NVQP+S + AN AVY LL P D I+G+ GGH+ Sbjct: 72 DIAEQLAIDRIKQVFGADYA----NVQPHSGSQANQAVYLALLQPGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KV+ + F ++ Y VN Q G IDYD+++ A + PK+++ G S+Y ++ Sbjct: 128 THG------AKVNVSGKLFYAVQYGVNEQ-GLIDYDEVQRLATEHKPKMVVAGFSAYSQK 180 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 D+AR R IAD GA L DMAHI+GLVAA SP ++ VVTSTTHK LRGPRGGII Sbjct: 181 IDWARFRAIADSVGAYLFVDMAHIAGLVAAGVYPSPMEHAHVVTSTTHKTLRGPRGGIIV 240 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 +G S + + K+ VFP +QGGP + IAA A+ K+ P + Sbjct: 241 --------AKGAS--------EELQKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y QQV+KNAQA+A+ L+ R ++V+GGT+NHL+L D+ ++GK+ E HI++ Sbjct: 285 KTYQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + D S G+R+GTPA+TTRG E D +A+++ Sbjct: 345 NKNSVPNDPRSPFVTSGLRLGTPAITTRGYQEQDSIDLANWI 386
>Q5GTS7:GLYA_WOLTR Serine hydroxymethyltransferase - Wolbachia sp. subsp. Brugia malayi| (strain TRS) Length = 425 Score = 304 bits (778), Expect = 1e-81 Identities = 173/407 (42%), Positives = 241/407 (59%), Gaps = 1/407 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D +++ +ERE RQ ++LIASENF +AV++A GS LTNKY+EG+ G RYY G +++ Sbjct: 19 DDEIYQSIERELQRQRSQLQLIASENFASKAVMEAQGSFLTNKYAEGYIGKRYYCGCEYV 78 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +R F + A NVQP+S + AN AV+ LL P D I+GL GGH+ Sbjct: 79 DEVENLAIERLCKLFNVRFA----NVQPHSGSQANQAVFASLLTPGDTILGLSISCGGHL 134 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG + +SG +F+S+ Y ++ T +D D++E A++ PK++I G S+YPR Sbjct: 135 THG----AAPNLSGK--WFKSIQYAIDRGTCLLDMDEVERLALEHKPKLIIAGASAYPRR 188 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF R R IADK A L+ D+AH +GL+AA E SP Y ++TSTTHK LRGPRGG++ Sbjct: 189 MDFKRFREIADKVSAYLLADIAHYAGLIAAGEYPSPAKYAHIITSTTHKTLRGPRGGVVI 248 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 ND K+ AVFP LQGGP + IAA A+ K+ PE+ Sbjct: 249 ------------------TNDEALHKKVQSAVFPGLQGGPLMHVIAAKAVAFKEALAPEF 290 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 KAYI++V++NA+ LA AL + ++TGGTD+H+VL DLR LTGK E I+ Sbjct: 291 KAYIKRVVENAKVLAQALQKHGLSVITGGTDSHIVLVDLRPQKLTGKGAVDSLERAGITC 350 Query: 1723 NKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 NK + D G+R GT A TTRG ++F+ IAD + Q Sbjct: 351 NKNSVPFDMEKPTITSGLRFGTAAETTRGLKAENFKEIADLINEVIQ 397
>Q7ND67:GLYA_GLOVI Serine hydroxymethyltransferase - Gloeobacter violaceus| Length = 426 Score = 304 bits (778), Expect = 1e-81 Identities = 180/414 (43%), Positives = 243/414 (58%), Gaps = 5/414 (1%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L DP V ++RE +RQ +ELIASENF AV+ A GS LTNKY+EG P RYYGG Sbjct: 8 LRATDPLVAGWIDRELNRQRSHLELIASENFTSAAVMAAQGSVLTNKYAEGLPSKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +DA+E++ RA FG A NVQP+S AN AV+ LL D+I+G++ Sbjct: 68 CEFVDAVEQIAIDRAKALFGAAHA----NVQPHSGAQANAAVFLALLERGDKILGMDLSH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + I+FE+L Y V+P + ID+D++ + A PK++ICG S+ Sbjct: 124 GGHLTHG------SPVNQSGIYFEALHYGVDPASHRIDFDQVRELAHAHRPKLIICGYSA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF R IAD+ GA L+ D+AHI+GLV A +P +CDVVT+TTHK LRGPRG Sbjct: 178 YPRVIDFECFREIADEVGAYLLADIAHIAGLVVAGVHPNPIPHCDVVTTTTHKTLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D + + AVFP QGGP + IAA A+ + Sbjct: 238 GLILTR------------------DEALGKRFDKAVFPGTQGGPLEHVIAAKAVAFGEAL 279 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y V+ NA+ALA L R LV+GGTDNHL+L DLR+ LTGK + + Sbjct: 280 QPEFKTYAADVVANARALAERLTARGLTLVSGGTDNHLMLVDLRSVDLTGKQADLLMSDV 339 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDF----EVIADFLIRAT 1857 +I+ NK I + G+R+G+PAMTTRG +F E+IA+ L + T Sbjct: 340 NITTNKNTIPFDPQSPFVTSGLRLGSPAMTTRGLGTTEFGEIGEIIANRLTQPT 393
>P24531:GLYA_CAMJE Serine hydroxymethyltransferase - Campylobacter jejuni| Length = 414 Score = 304 bits (778), Expect = 1e-81 Identities = 172/402 (42%), Positives = 236/402 (58%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D ++ L +E +RQ G+E+IASENF V++ +GS LTNKY+EG+PG RYYGG + + Sbjct: 7 DKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRYYGGCEFV 66 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D IE L +R F C NVQP S + AN VY L+ P D+I+G++ GGH+ Sbjct: 67 DEIETLAIERCKKLFN----CKFANVQPNSGSQANQGVYAALINPGDKILGMDLSHGGHL 122 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KVS + +ES Y V G IDY+K+ + A PK+++CG S+Y R Sbjct: 123 THG------AKVSSSGKMYESCFYGVELD-GRIDYEKVREIAKKEKPKLIVCGASAYARV 175 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFA+ R IAD+ GA L D+AHI+GLV A E SPF Y VV+STTHK LRGPRGGII Sbjct: 176 IDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAHVVSSTTHKTLRGPRGGIIM 235 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 ND + KIN A+FP +QGGP + IAA A+ K + E+ Sbjct: 236 ------------------TNDEELAKKINSAIFPGIQGGPLMHVIAAKAVGFKFNLSDEW 277 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y +QV NAQ LA+ L+ RK +LV+ GTDNHLVL +GK+ + I+ Sbjct: 278 KVYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGITA 337 Query: 1723 NKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + G+ G+R+GTPA+T RG E + E++++++ Sbjct: 338 NKNTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNYI 379
>Q8YGG7:GLYA_BRUME Serine hydroxymethyltransferase - Brucella melitensis| Length = 438 Score = 304 bits (778), Expect = 1e-81 Identities = 179/409 (43%), Positives = 234/409 (57%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L + DP++ + E RQ IELIASEN V RAVL+A GS LTNKY+EG+PG RY Sbjct: 17 NASLEDIDPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRY 76 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG Q++D +E L +RA FG + A NVQP S + N AV+ LL P D MGL+ Sbjct: 77 YGGCQYVDVVEELAIERAKKLFGAEFA----NVQPNSGSQMNQAVFLALLQPGDTFMGLD 132 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 SGGH++HG V+ + +F +SY V +D D++ A + PK+++ G Sbjct: 133 LNSGGHLTHG------SPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAG 186 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 G++Y R WD+ R R IAD+ GA LM DMAHI+GLVA + SP + V T+TTHK+LRG Sbjct: 187 GTAYSRIWDWKRFREIADEVGACLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRG 246 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I ND D KIN AVFP LQGGP + IA A+ Sbjct: 247 PRGGMIL------------------TNDADIAKKINSAVFPGLQGGPLMHVIAGKAVAFA 288 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+K Y + V+ NA+ALA L +V+GGTDNHL+L DLR TGK E Sbjct: 289 EALKPEFKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAAL 348 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK I + GVR+GTPA TTRG +F+ I + Sbjct: 349 GRANITCNKNGIPFDPEKPFVASGVRLGTPAGTTRGFGVAEFKEIGSLI 397
>Q57DY5:GLYA_BRUAB Serine hydroxymethyltransferase - Brucella abortus| Length = 438 Score = 304 bits (778), Expect = 1e-81 Identities = 179/409 (43%), Positives = 234/409 (57%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L + DP++ + E RQ IELIASEN V RAVL+A GS LTNKY+EG+PG RY Sbjct: 17 NASLEDIDPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRY 76 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG Q++D +E L +RA FG + A NVQP S + N AV+ LL P D MGL+ Sbjct: 77 YGGCQYVDVVEELAIERAKKLFGAEFA----NVQPNSGSQMNQAVFLALLQPGDTFMGLD 132 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 SGGH++HG V+ + +F +SY V +D D++ A + PK+++ G Sbjct: 133 LNSGGHLTHG------SPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAG 186 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 G++Y R WD+ R R IAD+ GA LM DMAHI+GLVA + SP + V T+TTHK+LRG Sbjct: 187 GTAYSRIWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRG 246 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I ND D KIN AVFP LQGGP + IA A+ Sbjct: 247 PRGGMIL------------------TNDADIAKKINSAVFPGLQGGPLMHVIAGKAVAFA 288 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+K Y + V+ NA+ALA L +V+GGTDNHL+L DLR TGK E Sbjct: 289 EALKPEFKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAAL 348 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK I + GVR+GTPA TTRG +F+ I + Sbjct: 349 GRANITCNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFGVAEFKEIGSLI 397
>Q2YN95:GLYA_BRUA2 Serine hydroxymethyltransferase - Brucella abortus (strain 2308)| Length = 438 Score = 304 bits (778), Expect = 1e-81 Identities = 179/409 (43%), Positives = 234/409 (57%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L + DP++ + E RQ IELIASEN V RAVL+A GS LTNKY+EG+PG RY Sbjct: 17 NASLEDIDPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRY 76 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG Q++D +E L +RA FG + A NVQP S + N AV+ LL P D MGL+ Sbjct: 77 YGGCQYVDVVEELAIERAKKLFGAEFA----NVQPNSGSQMNQAVFLALLQPGDTFMGLD 132 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 SGGH++HG V+ + +F +SY V +D D++ A + PK+++ G Sbjct: 133 LNSGGHLTHG------SPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAG 186 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 G++Y R WD+ R R IAD+ GA LM DMAHI+GLVA + SP + V T+TTHK+LRG Sbjct: 187 GTAYSRIWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRG 246 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I ND D KIN AVFP LQGGP + IA A+ Sbjct: 247 PRGGMIL------------------TNDADIAKKINSAVFPGLQGGPLMHVIAGKAVAFA 288 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+K Y + V+ NA+ALA L +V+GGTDNHL+L DLR TGK E Sbjct: 289 EALKPEFKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAAL 348 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK I + GVR+GTPA TTRG +F+ I + Sbjct: 349 GRANITCNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFGVAEFKEIGSLI 397
>Q8D7G5:GLYA2_VIBVU Serine hydroxymethyltransferase 2 - Vibrio vulnificus| Length = 431 Score = 304 bits (778), Expect = 1e-81 Identities = 188/455 (41%), Positives = 256/455 (56%), Gaps = 3/455 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L+ D V A ++ E RQ IELIASEN V +AV+ A G+ LTNKY+EG+PG RYYGG Sbjct: 18 LSATDDAVFAGIQAEFTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGG 77 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E + +RA F C NVQP+S AN AV LL P D IMG+ + Sbjct: 78 CEHVDTVEAIAIERAKKLFN----CEYANVQPHSGAQANGAVKLALLQPGDTIMGMSLDA 133 Query: 991 GGHVSHGYYTP-SGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 GGH++HG SGK +F ++ Y V+ +T I+YD + A++ PK++I GGS Sbjct: 134 GGHLTHGARPALSGK-------WFNAVQYGVDKETLEINYDDVRALAVEHKPKMIIAGGS 186 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 + PR DFA+ R IAD+ GA+LM DMAHI+GL+A SP + VVT+TTHK LRGPR Sbjct: 187 AIPRVIDFAKFREIADEVGAILMVDMAHIAGLIATGAHPSPLPHAHVVTTTTHKTLRGPR 246 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 GG+I N + KIN AVFP LQGGP + IAA A+ + Sbjct: 247 GGMIL------------------TNHEEIIKKINSAVFPGLQGGPLMHVIAAKAVAFGEA 288 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 PE+K YI V+ NA+ LA L R C +VTGGTD HL+L DLR GL G E+ E Sbjct: 289 LGPEFKTYIDSVIDNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNKAEEALER 348 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQ 1884 I+ NK I + + GVR+GTPA T+RG ++F++I ++ Sbjct: 349 AGITCNKNGIPFDTEKPMITSGVRLGTPAGTSRGFGAEEFKLIGHWI------------- 395 Query: 1885 HGKVQKEFLRGLENNKDIIE-LGNQVEAFASQFAM 1986 G V + E N ++ + + +V+A S+F + Sbjct: 396 -GDVLDGLVENPEGNAEVEQRVRKEVKALCSRFPL 429
>Q2S9R4:GLYA2_HAHCH Serine hydroxymethyltransferase 2 - Hahella chejuensis (strain KCTC| 2396) Length = 418 Score = 304 bits (778), Expect = 1e-81 Identities = 172/406 (42%), Positives = 241/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A DPD+ M+ E RQ IELIASEN+ V++A GS LTNKY+EG+P RYYGG Sbjct: 8 IASFDPDLWTAMQGETQRQEEHIELIASENYTSPRVMEAQGSALTNKYAEGYPNKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVY L P D I+G+ Sbjct: 68 CEYVDVVEQLAIDRAKELFGADYA----NVQPHSGSQANAAVYMALCKPGDVILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG VS + ++++ Y +NP+TG IDY+++ A + PK+++ G S+ Sbjct: 124 GGHLTHG------ASVSFSGRIYKAVQYGLNPETGEIDYEEVAKLARENKPKMIVAGFSA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R D+ R R IAD+ GA L DMAHI+GLVAA SP DV T+TTHK L GPRG Sbjct: 178 YSRVIDWERFRAIADEVGAYLFVDMAHIAGLVAAGVYPSPVQIADVTTTTTHKTLGGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + + + K K+NFAVFP QGGP + IAA A+ K+ Sbjct: 238 GLILAKANEELEK-----------------KLNFAVFPESQGGPLMHVIAAKAVCFKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 T E+K Y QV+KNA+ +A ++R +V+GGTD+HL L DL +TGK+ + Sbjct: 281 TDEFKQYQAQVVKNARVMADTFIQRGYDIVSGGTDDHLFLVDLIKKDITGKDADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+RIGTPA+T RG E + + + D++ Sbjct: 341 NITVNKNAVPNDPRSPFVTSGLRIGTPAITRRGMGEVEAKELTDWI 386
>Q9XAY7:GLYA_NEIMA Serine hydroxymethyltransferase - Neisseria meningitidis serogroup A| Length = 416 Score = 303 bits (777), Expect = 2e-81 Identities = 172/406 (42%), Positives = 245/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DPD+ A + +E RQ +ELIASEN+V AV++A GS LTNKY+EG+PG RYYGG Sbjct: 8 LAQYDPDLAAAIAQEDQRQQDHVELIASENYVSCAVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG A NVQP+S + AN AVY +L P D I+G+ Sbjct: 68 CEYVDIVEQLAIDRVKKLFGAQYA----NVQPHSGSQANQAVYASVLKPGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG + +SG + +++Y ++ + +DY ++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG----ASVNISGK--LYNAVTYGLD-ENEVLDYAEVERLALEHKPKMIVAGASA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + D+A+ R IADK GA L DMAH +GLVA E +P +CD VT+TTHK LRGPRG Sbjct: 177 YALQIDWAKFREIADKVGAYLFVDMAHYAGLVAGGEYPNPVPFCDFVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D E +N ++FPSLQGGP + IAA A+ K+ Sbjct: 237 GVILCR------------------DNTHEKALNSSIFPSLQGGPLMHVIAAKAVAFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y +QV NA A+A L++R R+V+G T++H+ L DL+ +TGK E Sbjct: 279 QPEFKQYAKQVKINAAAMAEELVKRGLRIVSGRTESHVFLVDLQPMKITGKAAEAALGKA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+RIG+ AMTTRG E D V+A+ + Sbjct: 339 HITVNKNAIPNDPEKPFVTSGIRIGSAAMTTRGFNEADARVLANLV 384
>Q9XAZ1:GLYA_NEIMF Serine hydroxymethyltransferase - Neisseria meningitidis serogroup C| / serotype 2a (strain ATCC 700532 / FAM18) Length = 416 Score = 303 bits (776), Expect = 2e-81 Identities = 171/406 (42%), Positives = 245/406 (60%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DPD+ A + +E RQ +ELIASEN+V AV++A GS LTNKY+EG+PG RYYGG Sbjct: 8 LAQYDPDLAAAIAQEDQRQQDHVELIASENYVSCAVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG A NVQP+S + AN AVY +L P D I+G+ Sbjct: 68 CEYVDIVEQLAIDRVKKLFGAQYA----NVQPHSGSQANQAVYASVLKPGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG + +SG + +++Y ++ + +DY ++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG----ASVNISGK--LYNAVTYGLD-ENEVLDYAEVERLALEHKPKMIVAGASA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + D+A+ R IADK GA L DMAH +GL+A E +P +CD VT+TTHK LRGPRG Sbjct: 177 YALQIDWAKFREIADKVGAYLFVDMAHYAGLIAGGEYPNPVPFCDFVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D E +N ++FPSLQGGP + IAA A+ K+ Sbjct: 237 GVILCR------------------DNTHEKALNSSIFPSLQGGPLMHVIAAKAVAFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y +QV NA A+A L++R R+V+G T++H+ L DL+ +TGK E Sbjct: 279 QPEFKQYAKQVKINAAAMAEELVKRGLRIVSGRTESHVFLVDLQPMKITGKAAEAALGKA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+RIG+ AMTTRG E D V+A+ + Sbjct: 339 HITVNKNAIPNDPEKPFVTSGIRIGSAAMTTRGFNEADARVLANLV 384
>Q474L3:GLYA1_RALEJ Serine hydroxymethyltransferase 1 - Ralstonia eutropha (strain| JMP134) (Alcaligenes eutrophus) Length = 415 Score = 303 bits (776), Expect = 2e-81 Identities = 169/405 (41%), Positives = 239/405 (59%), Gaps = 2/405 (0%) Frame = +1 Query: 637 EADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQ 816 + DP+V A +++E RQ IELIASEN+ AV+ A GS LTNKY+EG+PG RYYGG + Sbjct: 11 QIDPEVFAAIQKENQRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCE 70 Query: 817 HIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGG 996 ++D +E+L R FG + A NVQP S + AN VY +L P D IMG+ GG Sbjct: 71 YVDIVEQLAIDRVKQLFGAEAA----NVQPNSGSQANQGVYFAVLKPGDTIMGMSLAEGG 126 Query: 997 HVSHGY-YTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSY 1173 H++HG SGK +F +SY +N Q IDYD LE A + PK++I G S++ Sbjct: 127 HLTHGMALNMSGK-------WFNVVSYGLNAQED-IDYDALEKLAQEKKPKLIIAGASAF 178 Query: 1174 PREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGG 1353 DF R+ +A GA M DMAH +GL+AA +P + D VT+TTHK+LRGPRGG Sbjct: 179 ALRIDFERIGKVAKSIGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 238 Query: 1354 IIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVAT 1533 +I + + E IN ++FP +QGGP + IA A+ K+ T Sbjct: 239 VILMKA-------------------EHEKAINSSIFPGIQGGPLMHVIAGKAVAFKEALT 279 Query: 1534 PEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCH 1713 PE+KAY +QV+KNA LA L+ R R+V+G T++H++L DLR +TGK E++ H Sbjct: 280 PEFKAYQEQVVKNAAVLAETLIARGLRIVSGRTESHVMLVDLRAKNITGKEAERILGEAH 339 Query: 1714 ISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +++NK I D G+R+G+PAMTTRG E++ ++ + + Sbjct: 340 LTVNKNAIPNDPEKPFVTSGIRVGSPAMTTRGFKEEEARIVGNLI 384
>Q87I03:GLYA2_VIBPA Serine hydroxymethyltransferase 2 - Vibrio parahaemolyticus| Length = 431 Score = 303 bits (775), Expect = 3e-81 Identities = 178/407 (43%), Positives = 239/407 (58%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L+ D V A ++ E RQ IELIASEN V +AV+ A G+ LTNKY+EG+PG RYYGG Sbjct: 18 LSATDDAVFAGIQAEFTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGG 77 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E + +RA F C NVQP+S AN AV LL P D I+G+ + Sbjct: 78 CEHVDTVEAIAIERAKKLFN----CEYANVQPHSGAQANGAVKLALLQPGDTILGMSLDA 133 Query: 991 GGHVSHGYYTP-SGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 GGH++HG SGK +F ++ Y V+ +T I+YD + A++ PK++I GGS Sbjct: 134 GGHLTHGARPALSGK-------WFNAVQYGVDRETLEINYDDVRALALEHKPKMIIAGGS 186 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 + PR DFA+ R IAD+ A+LM DMAHI+GL+A SP + VVT+TTHK LRGPR Sbjct: 187 AIPRTIDFAKFREIADEVNAILMVDMAHIAGLIATGAHPSPLPHAHVVTTTTHKTLRGPR 246 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 GG+I N D KIN AVFP LQGGP + IAA A+ + Sbjct: 247 GGMIL------------------TNHEDIIKKINSAVFPGLQGGPLMHVIAAKAVAFGEA 288 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 PE+K YI V+ NA+ LA L R C +VTGGTD HL+L DLR GL G E+ E Sbjct: 289 LGPEFKTYIDSVINNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNKAEEALER 348 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + + G+R+GTPA T+RG ++F++I +++ Sbjct: 349 AGITCNKNGIPFDTEKPMITSGIRLGTPAGTSRGFGAEEFKLIGNWI 395
>Q6YR37:GLYA_ONYPE Serine hydroxymethyltransferase - Onion yellows phytoplasma| Length = 416 Score = 302 bits (774), Expect = 3e-81 Identities = 176/412 (42%), Positives = 246/412 (59%), Gaps = 4/412 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + D ++ L+E+E+ RQ I LIASENFV +AVLDA GS LTNKY+EG+P ARYY G Sbjct: 7 LKDQDQEIFDLIEQEKIRQKENILLIASENFVSQAVLDAQGSILTNKYAEGYPQARYYNG 66 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D IE++ QRA FG A NVQP+S + AN+ + LL P D+I+GL Sbjct: 67 CKNVDQIEKIAIQRATKLFGAKYA----NVQPHSGSQANMGAFQALLKPGDKILGLSLMD 122 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG+ K+S + F+E+ Y V+PQT +DYD++ A+ PK++I G S+ Sbjct: 123 GGHLTHGH------KLSFSGGFYEAHFYNVHPQTEMLDYDEIRKVALKVKPKLIIAGYSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFD-YCDVVTSTTHKNLRGPR 1347 Y + +F + R IAD+ A LM D+AHI+GLVA PF+ DVVTST HK LRGPR Sbjct: 177 YSKTINFKKFRQIADEVNAYLMADIAHIAGLVACGLHPCPFEANADVVTSTMHKTLRGPR 236 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 GG+I K + + KIN +FP +QGGP + IAA A+ ++ Sbjct: 237 GGLILTNKEEVFK------------------KINRGIFPGIQGGPCIHTIAAKAVAFQEA 278 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFG--LTGKNFEKVC 1701 P +K Y +QV+KNA A A ++ R+V+GGTDNHL L D++ TG + Sbjct: 279 MMPSFKEYQKQVIKNANTFAKAFQQKGYRIVSGGTDNHLFLIDVKHKNPEFTGSKIANML 338 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 E +I +NK I + G+RIGTPAMTT G E+DF ++AD + +A Sbjct: 339 EKINIVVNKNTIPFDQEKPFVTSGIRIGTPAMTTVGFRENDFILVADLMDKA 390
>Q30R29:GLYA1_THIDN Serine hydroxymethyltransferase 1 - Thiomicrospira denitrificans| (strain ATCC 33889 / DSM 1351) Length = 415 Score = 302 bits (774), Expect = 3e-81 Identities = 178/434 (41%), Positives = 252/434 (58%), Gaps = 7/434 (1%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L E D D+ L E+E +RQ +E+IASENF AV++A+GS TNKY+EG+P RYYGG Sbjct: 4 LKEFDKDIFDLCEKELERQSNHLEMIASENFTLPAVMEAMGSVFTNKYAEGYPAKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 ++ D +E+L RA FG C NVQP+S + AN AVY LL D+++G++ Sbjct: 64 CEYADGVEQLAIDRACKLFG----CNYANVQPHSGSQANAAVYAALLKAGDKLLGMDLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG K S + + S +Y V G ++YDK+ + A PKI++CG S+ Sbjct: 120 GGHLTHG------SKPSFSGQNYSSFTYGVELD-GRMNYDKILEIAKAVQPKIIVCGASA 172 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y RE DF + R IAD GA++ D+AH++GLV A E SPF + VVT+TTHK L GPRG Sbjct: 173 YAREIDFKKFREIADAVGAIMFADIAHVAGLVVAGEHMSPFPHAHVVTTTTHKTLAGPRG 232 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ND D KIN A+FP +QGGP + IAA A+ K Sbjct: 233 GMIM------------------TNDEDIAKKINSAIFPGIQGGPLVHVIAAKAVGFKYNL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 + E+K Y QV NA+ L L++R LV+GGTDNHLVL +GK+ + Sbjct: 275 SAEWKDYAVQVKANAKILGEVLVKRGYDLVSGGTDNHLVLLSFLNRDFSGKDADIALGNA 334 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL------IRATQIAG 1869 I++NK + G+ S G+RIG+PA+T+RG E +FE IA+ + I T++ Sbjct: 335 GITVNKNTVPGETRSPFVTSGIRIGSPALTSRGMKEREFEFIANKIADVLDDINNTKLQE 394 Query: 1870 SVLKQHGKVQKEFL 1911 SV K+ ++ ++F+ Sbjct: 395 SVKKELKELAQKFV 408
>Q7NBH8:GLYA_MYCGA Serine hydroxymethyltransferase - Mycoplasma gallisepticum| Length = 414 Score = 302 bits (773), Expect = 5e-81 Identities = 172/421 (40%), Positives = 248/421 (58%), Gaps = 2/421 (0%) Frame = +1 Query: 649 DVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHIDA 828 ++ L+ +E RQ IELIASEN+V AVL A GS LTNKY+EG P RYYGG +++D Sbjct: 7 EIFKLINQELQRQQDQIELIASENYVSEAVLRATGSVLTNKYAEGTPNKRYYGGCEYVDQ 66 Query: 829 IERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHVSH 1008 IE + ++ FG A NVQP+S ++AN A Y LL P+D+++ + GGH++H Sbjct: 67 IELIAIEKLKKLFGARHA----NVQPHSGSTANAAAYLALLQPHDKVLAMGLNDGGHLTH 122 Query: 1009 GYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPREWD 1188 G KV+ + ++ Y V+P T +DYD++ +A++ PK+++CG S+Y R D Sbjct: 123 G------SKVNFSGKIYDFYHYNVDPNTYLLDYDEILKKAIEVKPKLIVCGASNYSRAID 176 Query: 1189 FARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIFFR 1368 FA+ R IAD A LM D+AHI+GL+ A ++P +YCD++TSTTHK LRGPRGGII Sbjct: 177 FAKFRQIADHVSAYLMADIAHIAGLIVAGYHQNPVEYCDIITSTTHKTLRGPRGGIIL-- 234 Query: 1369 KGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEYKA 1548 N D KI+ AVFP GGP + IAA AI + P++K Sbjct: 235 ----------------TNREDLIKKIDSAVFPGELGGPLMHVIAAKAIAFDEALQPKFKT 278 Query: 1549 YIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDL-RTFGLTGKNFEKVCELCHISIN 1725 YI+ V+ N++A A + + +++ GTDNHL +L + F LTG E +I +N Sbjct: 279 YIKNVIDNSKAFCEAFINKGYQIIANGTDNHLFSINLFKKFNLTGDLVENWLYQANIVVN 338 Query: 1726 KTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQHGKVQK 1902 K I Y N S++P G+R+GT AMT+RG ++ DF IAD++ + + G L KV+ Sbjct: 339 KNMIPYDSNKSMNPSGIRLGTAAMTSRGLVQSDFVQIADWIDQIIKAKGD-LNVINKVKS 397 Query: 1903 E 1905 E Sbjct: 398 E 398
>Q2RFW7:GLYA_MOOTA Serine hydroxymethyltransferase - Moorella thermoacetica (strain ATCC| 39073) Length = 416 Score = 302 bits (773), Expect = 5e-81 Identities = 173/405 (42%), Positives = 241/405 (59%), Gaps = 1/405 (0%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 + +A+ DP++ A + E RQ +ELIASENFV +AV++A LTNKY+EG+PG RYY Sbjct: 4 ETVAKVDPEIVAAVRGELQRQRTHLELIASENFVSQAVMEAYSCVLTNKYAEGYPGKRYY 63 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG + D +E L +RA FG + A NVQP+S + AN AVY +L P D+ +G+ Sbjct: 64 GGCEWADVVENLARERAKALFGAEHA----NVQPHSGSQANTAVYLAVLNPGDKALGMNL 119 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 GGH++HG VS + ++ Y V+ +TG IDYD + A + P++++ G Sbjct: 120 AHGGHLTHG------SPVSLSGKYYNFCFYGVDAKTGRIDYDAVARIAREERPRLIVAGA 173 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S+YPR DFAR R IAD+ GA+LM DMAHI+GLVAA +P Y VT+TTHK +RGP Sbjct: 174 SAYPRVIDFARFREIADEVGALLMVDMAHIAGLVAAGIHPNPVPYAHFVTTTTHKTMRGP 233 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 RGGII + ++ I+ AVFP +QGGP + IAA A+ LK+ Sbjct: 234 RGGIILTTR-------------------EYARDIDKAVFPGVQGGPLMHVIAAKAVALKE 274 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 PE+K Y +Q++ NA+ LA AL+ LV+GGTDNHL+L DLR +TG+ E + Sbjct: 275 AMLPEFKRYQEQIVTNARTLADALMGYGFNLVSGGTDNHLMLVDLRNKNITGREAEDILA 334 Query: 1705 LCHISINKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIA 1836 I++NK I D S G+R+GT A+T+RG D +A Sbjct: 335 SVQITVNKNAIPFDPQKPSVTSGIRLGTAALTSRGMDADAMVQVA 379
>Q97GV1:GLYA_CLOAB Serine hydroxymethyltransferase - Clostridium acetobutylicum| Length = 411 Score = 302 bits (773), Expect = 5e-81 Identities = 165/403 (40%), Positives = 242/403 (60%), Gaps = 1/403 (0%) Frame = +1 Query: 640 ADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQH 819 +D +V++++E E RQ IELIASENF +AV++A+GS+LTNKY+EG+PG RYYGG Sbjct: 9 SDSEVYSIIEEENARQENNIELIASENFTSKAVMEAMGSYLTNKYAEGYPGKRYYGGCYV 68 Query: 820 IDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGH 999 +D +E L +RA F + A NVQP+S + AN+AVY +L P D IMG+ GGH Sbjct: 69 VDKVEELARERAKKLFKAEHA----NVQPHSGSQANMAVYFAVLKPGDTIMGMNLTDGGH 124 Query: 1000 VSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPR 1179 ++HG V+ + F ++Y V+ +T IDY+ +A++ PK+++ G S+Y R Sbjct: 125 LTHG------SPVNFSGKLFNIIAYGVSDETEQIDYEAFRKKALECKPKMIVSGASAYSR 178 Query: 1180 EWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGII 1359 DF ++R I D+ GA +M DMAHI+GLVAA SP Y D VT+TTHK LRGPRGG I Sbjct: 179 IIDFKKIREICDEVGAYMMVDMAHIAGLVAAGLHPSPIPYADFVTTTTHKTLRGPRGGAI 238 Query: 1360 FFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPE 1539 F ++ + I+ +VFP +QGGP + IA A+ + + Sbjct: 239 FCKE-------------------KYAKDIDKSVFPGMQGGPLMHIIAGKAVCFGEALKDD 279 Query: 1540 YKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHIS 1719 +K Y QQ++ NA+ A L + R+V+GGTDNHL+L DL +TGK+ E + + I+ Sbjct: 280 FKDYAQQIVNNAKVFADELTKYGFRIVSGGTDNHLLLVDLTNKNITGKDAEHLLDSVGIT 339 Query: 1720 INKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK I + G+R+GTP++TTRG E++ + +A F+ Sbjct: 340 ANKNTIPFEKKSPFITSGIRMGTPSVTTRGFKEEEMKKVAYFI 382
>Q5HW65:GLYA_CAMJR Serine hydroxymethyltransferase - Campylobacter jejuni (strain| RM1221) Length = 414 Score = 302 bits (773), Expect = 5e-81 Identities = 171/402 (42%), Positives = 236/402 (58%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D ++ L +E +RQ G+E+IASENF V++ +GS LTNKY+EG+PG RYYGG + + Sbjct: 7 DKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRYYGGCEFV 66 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D IE L +R F C NVQP S + AN VY L+ P D+I+G++ GGH+ Sbjct: 67 DEIETLAIERCKKLFN----CKFANVQPNSGSQANQGVYAALINPGDKILGMDLSHGGHL 122 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG KVS + +ES Y V G IDY+K+ + A PK+++CG S+Y R Sbjct: 123 THG------AKVSSSGKMYESCFYGVELD-GRIDYEKVREIAKKEKPKLIVCGASAYARV 175 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFA+ R IAD+ GA L D+AHI+GLV A E SPF + VV+STTHK LRGPRGGII Sbjct: 176 IDFAKFREIADEVGAYLFADIAHIAGLVVAGEHPSPFPHAHVVSSTTHKTLRGPRGGIIM 235 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 ND + KIN A+FP +QGGP + IAA A+ K + E+ Sbjct: 236 ------------------TNDEELAKKINSAIFPGIQGGPLMHVIAAKAVGFKFNLSDEW 277 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y +QV NAQ LA+ L+ RK +LV+ GTDNHLVL +GK+ + I+ Sbjct: 278 KVYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGITA 337 Query: 1723 NKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + G+ G+R+GTPA+T RG E + E++++++ Sbjct: 338 NKNTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNYI 379
>P24060:GLYA_BRAJA Serine hydroxymethyltransferase - Bradyrhizobium japonicum| Length = 432 Score = 302 bits (773), Expect = 5e-81 Identities = 174/406 (42%), Positives = 234/406 (57%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L +ADP++ A ++ E RQ +ELIASEN V RAVL+A GS +TNKY+EG+PGARYYGG Sbjct: 18 LDQADPEIAAAIKGELGRQRHEVELIASENIVSRAVLEAQGSVMTNKYAEGYPGARYYGG 77 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E L RA FG A NVQP S + N AV+ LL P D MGL+ + Sbjct: 78 CEWVDVAENLAIDRAKKLFGAGFA----NVQPNSGSQMNQAVFLALLQPGDTFMGLDLAA 133 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F++ Y V + ID D ++ +A + PK+++ GGS+ Sbjct: 134 GGHLTHG------SPVNMSGKWFKAAHYTVRREDQIIDMDAVQKQAEEIKPKLIVAGGSA 187 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R WDF R R IAD GA L+ DMAH +GLVA SP Y V T+TTHK+LRGPRG Sbjct: 188 YSRAWDFKRFREIADSVGAYLLVDMAHFAGLVAGGVHASPVPYAHVTTTTTHKSLRGPRG 247 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ND K+N A+FP LQGGP + IAA A+ + Sbjct: 248 GLIL------------------SNDETLAKKLNSAIFPGLQGGPLMHVIAAKAVAFGEAL 289 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P++K Y + V++NA+ALA A+ +V+GGTDNHL+L DLR GL G EK Sbjct: 290 RPDFKVYAKNVVENAKALAEAMKSHGFDIVSGGTDNHLMLVDLRPKGLKGNVSEKALVRA 349 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + G+R+GTPA TTRG +F+ + + Sbjct: 350 AITCNKNGIPFDPEKPFVTSGLRLGTPAATTRGFGVAEFQQVGGMI 395
>Q2NIT8:GLYA_AYWBP Serine hydroxymethyltransferase - Aster yellows witches'-broom| phytoplasma (strain AYWB) Length = 429 Score = 302 bits (773), Expect = 5e-81 Identities = 176/412 (42%), Positives = 245/412 (59%), Gaps = 4/412 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + D ++ L+E+E+ RQ I LIASENFV +AVLDA GS LTNKY+EG+P ARYY G Sbjct: 20 LKDQDQEIFDLIEQEKARQKENILLIASENFVSQAVLDAQGSILTNKYAEGYPQARYYNG 79 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D IE++ QRA FG A NVQP+S + AN+ V+ LL P D+I+GL Sbjct: 80 CKNVDQIEKIAIQRATKLFGAKYA----NVQPHSGSQANMGVFQALLKPGDKILGLSLMD 135 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG+ K+S + F+E+ Y VNPQT +DYD++ A+ PK++I G S+ Sbjct: 136 GGHLTHGH------KLSFSGGFYEAHFYNVNPQTEMLDYDEIRKVALAVKPKLIIAGYSA 189 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFD-YCDVVTSTTHKNLRGPR 1347 Y + +F + R IAD+ A L+ D+AHI+GLVA PF+ DVVTST HK LRGPR Sbjct: 190 YSKTINFKKFRQIADEVNAYLIADIAHIAGLVACGLHPCPFEANADVVTSTMHKTLRGPR 249 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 GG+I K + + KIN +FP +QGGP + IAA A+ ++ Sbjct: 250 GGLILTNKEELFK------------------KINRGIFPGIQGGPCIHTIAAKAVAFQEA 291 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDL--RTFGLTGKNFEKVC 1701 P +K Y +QV+KNA A A ++ R+V+G TDNHL L D+ + TG + Sbjct: 292 MMPSFKEYQKQVIKNANTFAKAFQQKGYRIVSGSTDNHLFLIDVKHKNTEFTGAKIANML 351 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 E +I +NK I + G+RIGTPAMTT G E+DF +AD + +A Sbjct: 352 EKINIVVNKNTIPFDQEKPFVTSGIRIGTPAMTTVGFRENDFVAVADLMDKA 403
>Q2G646:GLYA_NOVAD Serine hydroxymethyltransferase - Novosphingobium aromaticivorans| (strain DSM 12444) Length = 436 Score = 301 bits (772), Expect = 6e-81 Identities = 179/402 (44%), Positives = 231/402 (57%), Gaps = 1/402 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L AD +V A + E RQ IELIASEN AVL+A GS TNKY+EG+PG RYYGG Sbjct: 20 LETADAEVFAAIRGELKRQQTKIELIASENITSLAVLEATGSVFTNKYAEGYPGKRYYGG 79 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 ++ D +E L +RA FG C NVQP S + N AV+ LL P D MGL+ S Sbjct: 80 CEYADVVENLAIERAKKLFG----CNFANVQPNSGSQMNQAVFLALLQPGDSFMGLDLNS 135 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F+ + Y V ID D++ A + PK++I GG++ Sbjct: 136 GGHLTHG------SPVNMSGKWFKPIPYGVRADDHLIDMDEVARLARENKPKLIIAGGTA 189 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R WDF R R IAD+ GA L+ DM+H SGLVA SPF + VVTSTTHK+LRGPR Sbjct: 190 YSRVWDFKRFREIADEVGAWLLVDMSHFSGLVAGGAHPSPFPHAHVVTSTTHKSLRGPRS 249 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 GII ND D K N AVFP +QGGP + IAA A+ + Sbjct: 250 GIIL------------------TNDEDLAKKFNMAVFPGMQGGPLVHVIAAKAVAFGEAL 291 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+KAY Q++ NA+ALA A+ +V+GGTDNHL+L DL +TGK EK + Sbjct: 292 RPEFKAYAAQIVANARALAEAVKDAGLSVVSGGTDNHLMLVDLSAKDVTGKAAEKGLDRA 351 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVI 1833 ++ NK + D S G+R+GTPA TTRG E++F I Sbjct: 352 WLTCNKNGVPFDKRSPFVTSGIRLGTPAGTTRGFREEEFRKI 393
>Q74LC1:GLYA_LACJO Serine hydroxymethyltransferase - Lactobacillus johnsonii| Length = 411 Score = 301 bits (772), Expect = 6e-81 Identities = 176/406 (43%), Positives = 243/406 (59%), Gaps = 2/406 (0%) Frame = +1 Query: 637 EADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQ 816 E P + ++ E RQ IELIASEN V AV +A GS LTNKY+EG+PG RYYGG Q Sbjct: 5 EKSPALWDAIKSEEKRQEDTIELIASENIVSDAVREAQGSVLTNKYAEGYPGKRYYGGCQ 64 Query: 817 HIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGG 996 +ID +E+L A F + A NVQP+S + AN+ VY LL P D I+G+ +GG Sbjct: 65 YIDKVEQLAIDYAKKLFNAEYA----NVQPHSGSQANMTVYNALLKPGDTILGMGMDAGG 120 Query: 997 HVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYP 1176 H++HG KV+ + F S+SY +NP+T +D+D++ A++ PK++I G S+Y Sbjct: 121 HLTHG------SKVNFSGKIFNSISYDLNPETEELDFDRIRQLAIEKKPKLIIAGASAYS 174 Query: 1177 REWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGI 1356 R D+ + R IAD+ GA LM DMAHI+GLVA SP DVVT+TTHK LRGPRGG+ Sbjct: 175 RIIDWQKFREIADEVGAYLMVDMAHIAGLVATGAHPSPVPIADVVTTTTHKTLRGPRGGM 234 Query: 1357 IFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATP 1536 I N+ + KI+ A+FP QGGP + IAA A + P Sbjct: 235 IL------------------SNNKELGKKIDSALFPGTQGGPLEHVIAAKAQAFYEDLQP 276 Query: 1537 EYKAYIQQVMKNAQALASALLRRK-CRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCH 1713 E+ YI QV+KN++A+A K R+V+GGTDNHL++ D+ G+TGK+ + + + + Sbjct: 277 EFTQYIDQVIKNSKAMAEEFKNSKNIRVVSGGTDNHLMIIDITKTGVTGKDAQNLLDSVN 336 Query: 1714 ISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 I+ NK I GD S G+RIGTPA+T+RG E D + +A +I Sbjct: 337 ITTNKESIPGDKRSPFITSGLRIGTPAITSRGFKEPDAKEVAKIII 382
>Q3SRV3:GLYA_NITWN Serine hydroxymethyltransferase - Nitrobacter winogradskyi (strain| Nb-255 / ATCC 25391) Length = 433 Score = 301 bits (770), Expect = 1e-80 Identities = 179/406 (44%), Positives = 233/406 (57%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LAEADP++ A + E RQ IELIASEN V RAVL+A GS +TNKY+EG+PGARYYGG Sbjct: 19 LAEADPEIAAAITGELGRQRHEIELIASENIVSRAVLEAQGSVMTNKYAEGYPGARYYGG 78 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E L +RA FG A NVQP S + N AV+ LL P D MGL+ + Sbjct: 79 CEWVDVAETLAIERAKKLFGARFA----NVQPNSGSQMNQAVFLALLQPGDTFMGLDLAA 134 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F+ Y V ID D++ RA + PK++I GGS+ Sbjct: 135 GGHLTHG------APVNMSGKWFKVAHYTVRRDDHLIDMDEVARRAEEVKPKLIIAGGSA 188 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R WDF R R IAD GA LM DMAH +GLVA SP + V T+TTHK+LRGPRG Sbjct: 189 YSRPWDFKRFREIADSVGAYLMVDMAHFAGLVAGGVHASPVPHAHVTTTTTHKSLRGPRG 248 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ND K N A+FP LQGGP + IAA A+ L + Sbjct: 249 GLILC------------------NDEALAKKFNSAIFPGLQGGPLMHVIAAKAVALGEAL 290 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P++K Y + V++NA+ALA +L +V+GGTDNHL+L DLR GL G EK Sbjct: 291 RPDFKIYAKNVVENARALAESLRGHGFDIVSGGTDNHLMLVDLRPKGLKGNVSEKALVRA 350 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 ++ NK I + G+R+GTPA TTRG +F+ + + Sbjct: 351 GLTCNKNGIPFDPEKPFVTSGLRLGTPATTTRGFGVSEFKQVGGLI 396
>Q7VUW7:GLYA_BORPE Serine hydroxymethyltransferase - Bordetella pertussis| Length = 415 Score = 301 bits (770), Expect = 1e-80 Identities = 167/409 (40%), Positives = 241/409 (58%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L + DPDV A +++E RQ + IELIASEN+ AV+ A G+ LTNKY+EG+PG RY Sbjct: 5 NLTLDQVDPDVWAAIQKEDVRQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRY 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +++D +E+L R FG + A NVQP S + AN VY +L P D ++G+ Sbjct: 65 YGGCEYVDVVEQLAIDRLKQIFGAEAA----NVQPNSGSQANQGVYMAVLKPGDTVLGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG V+ + + + Y ++ +DY ++E + PK+++ G Sbjct: 121 LAEGGHLTHG------ASVNASGKLYNFVPYGLDADE-VLDYAQVERLTKEHKPKLIVAG 173 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y DF RM IA GA+ M D+AH +GLVA +P + D VTSTTHK+LRG Sbjct: 174 ASAYALHIDFERMARIAHDNGALFMVDIAHYAGLVAGGAYPNPVPHADFVTSTTHKSLRG 233 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I + +FE +N A+FP +QGGP + IAA A+ K Sbjct: 234 PRGGVIMMKA-------------------EFEKAVNSAIFPGIQGGPLMHVIAAKAVAFK 274 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + +PE++ Y QQV+KNA+ LA L++R R+V+G T++H++L DLR G+TGK E V Sbjct: 275 EALSPEFQDYAQQVVKNAKVLADTLVKRGLRIVSGRTESHVMLVDLRPKGITGKEAEAVL 334 Query: 1702 ELCHISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+R+GTPAMTTRG E + E+ A+ + Sbjct: 335 GQAHITVNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTANLI 383
>Q7WFD2:GLYA2_BORBR Serine hydroxymethyltransferase 2 - Bordetella bronchiseptica| (Alcaligenes bronchisepticus) Length = 415 Score = 301 bits (770), Expect = 1e-80 Identities = 167/409 (40%), Positives = 241/409 (58%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L + DPDV A +++E RQ + IELIASEN+ AV+ A G+ LTNKY+EG+PG RY Sbjct: 5 NLTLDQVDPDVWAAIQKEDVRQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRY 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +++D +E+L R FG + A NVQP S + AN VY +L P D ++G+ Sbjct: 65 YGGCEYVDVVEQLAIDRLKQIFGAEAA----NVQPNSGSQANQGVYMAVLKPGDTVLGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG V+ + + + Y ++ +DY ++E + PK+++ G Sbjct: 121 LAEGGHLTHG------ASVNASGKLYNFVPYGLDADE-VLDYAQVERLTKEHKPKLIVAG 173 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y DF RM IA GA+ M D+AH +GLVA +P + D VTSTTHK+LRG Sbjct: 174 ASAYALHIDFERMARIAHDNGALFMVDIAHYAGLVAGGAYPNPVPHADFVTSTTHKSLRG 233 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I + +FE +N A+FP +QGGP + IAA A+ K Sbjct: 234 PRGGVIMMKA-------------------EFEKAVNSAIFPGIQGGPLMHVIAAKAVAFK 274 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + +PE++ Y QQV+KNA+ LA L++R R+V+G T++H++L DLR G+TGK E V Sbjct: 275 EALSPEFQDYAQQVVKNAKVLADTLVKRGLRIVSGRTESHVMLVDLRPKGITGKEAEAVL 334 Query: 1702 ELCHISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+R+GTPAMTTRG E + E+ A+ + Sbjct: 335 GQAHITVNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTANLI 383
>Q2RVA2:GLYA1_RHORT Serine hydroxymethyltransferase 1 - Rhodospirillum rubrum (strain| ATCC 11170 / NCIB 8255) Length = 434 Score = 301 bits (770), Expect = 1e-80 Identities = 178/407 (43%), Positives = 240/407 (58%), Gaps = 1/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L+ AD V + +E RQ IELIASENFV +AVL+A GS LTNKY+EG+P RYYGG Sbjct: 23 LSAADDAVAIAIAQETTRQRESIELIASENFVSKAVLEAQGSVLTNKYAEGYPQRRYYGG 82 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 ++D +E L R FG A NVQP+S + AN AV+ LL P D I+GL+ + Sbjct: 83 CANVDRVEDLAIARLNQLFGSTYA----NVQPHSGSQANQAVFLALLAPGDTILGLDLKA 138 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG + +SG +F ++SY V+P+T ID +++ D A PK+LI GGS+ Sbjct: 139 GGHLTHG----APVNISGR--WFTAVSYGVDPRTHLIDMEQMADLARRHRPKLLIAGGSA 192 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DFAR R IAD+ GA+LM DMAH +GLVA SP + DV+TSTTHK LRGPRG Sbjct: 193 YPRLLDFARFRQIADEVGAILMVDMAHFAGLVAGGVYPSPVPFADVITSTTHKTLRGPRG 252 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G + ND KIN AVFP LQGGP + IAA A+ + Sbjct: 253 GFVL------------------TNDAAIAKKINSAVFPGLQGGPLMHIIAAKAVAFGEAL 294 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P +K Y ++V++N + LA LL + +GGTD HL + DLR G+TG E+ E Sbjct: 295 DPSFKIYARRVVENCRVLAQTLLDGGLAITSGGTDCHLAVVDLRPLGVTGTIAEQALESI 354 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 I++NK I D + G+R+G+ A T+RG +++ IA ++ Sbjct: 355 GITLNKNAIPNDPEKPMVTSGIRVGSAAGTSRGFGPEEYRRIAALIL 401
>Q3IRX5:GLYA_NATPD Serine hydroxymethyltransferase - Natronomonas pharaonis (strain DSM| 2160 / ATCC 35678) Length = 424 Score = 300 bits (769), Expect = 1e-80 Identities = 176/410 (42%), Positives = 240/410 (58%), Gaps = 3/410 (0%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 + + EADP + A + ERDRQ + +IASEN V AVL A S LTNKY+EG+PG RYY Sbjct: 4 EQVREADPAIAAALADERDRQEDTLAMIASENHVSEAVLQAQSSELTNKYAEGYPGERYY 63 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 G D +E L +RA +G + +NVQP+S T AN+AVY +L P DRI+ LE Sbjct: 64 AGCGPADDVEELAIERAEELWGAEH----INVQPHSGTQANMAVYLAMLEPGDRILSLEL 119 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 GGH+SHG+ +G + +E Y+V+P+TGYIDYD+L ++A F P I++ G Sbjct: 120 EHGGHLSHGHPA----NFTGQT--YEVEQYEVDPETGYIDYDELHEQAEAFEPDIIVSGY 173 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S+YPRE +F R++ AD A + D+AHI+GLVAA +SP D VT +THK +R Sbjct: 174 SAYPREVEFERIQEAADAVDAYHLADIAHITGLVAAGVHQSPVGVADFVTGSTHKTIRAG 233 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 RGGI+ D ++ D I+ AVFP QGGP +++A A+ K+ Sbjct: 234 RGGIVMC-------------------DEEYADDIDAAVFPGAQGGPLMHNVAGKAVGFKE 274 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTF--GLTGKNFEKV 1698 PE++ Y QQV+ NA+AL L LV+GGTDNHLVL DLR +G E+ Sbjct: 275 ALQPEFEQYAQQVIDNAEALGERLQEHGFSLVSGGTDNHLVLVDLRESHPDTSGTVAEEA 334 Query: 1699 CELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 E I +NK + G+ S +P G+R GTPA+TTRG E E +AD + Sbjct: 335 LEAAGIVLNKNTVPGETRSAFNPSGIRAGTPALTTRGFDEQACERVADII 384
>Q2KV15:GLYA_BORA1 Serine hydroxymethyltransferase - Bordetella avium (strain 197N)| Length = 416 Score = 300 bits (769), Expect = 1e-80 Identities = 165/406 (40%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + DPD+ A +++E +RQ + IELIASEN+ AV+ A G+ LTNKY+EG+PG RYYGG Sbjct: 8 LDKVDPDLWAAIQKEDERQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG + A NVQP S + AN VY +L P D ++G+ Sbjct: 68 CEYVDIVEQLAIDRLKELFGAEAA----NVQPNSGSQANQGVYMAVLKPGDTVLGMSLAE 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + LSY ++ + ++Y ++E A + PK+++ G S+ Sbjct: 124 GGHLTHG------ASVNASGKLYNFLSYGLD-ENEVLNYAQVEALAREHKPKLIVAGASA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y DF RM IA + GA+ M D+AH +GLVA + +P + D VTSTTHK+LRGPRG Sbjct: 177 YALHIDFERMARIARENGALFMVDIAHYAGLVAGGQYPNPVPHADFVTSTTHKSLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + E +N A+FP +QGGP + IAA A+ K+ Sbjct: 237 GVIMMKA-------------------QHEKAVNSAIFPGIQGGPLEHVIAAKAVAFKEAL 277 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 +PE+K Y QV+KNA+ LA L++R R+V+G T++H++L DLR G+TGK E V Sbjct: 278 SPEFKDYASQVVKNAKVLAETLVKRGLRIVSGRTESHVMLVDLRAKGITGKEAEAVLGKA 337 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+R+GTPAMTTRG E + E+ + + Sbjct: 338 HITVNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTGNLI 383
>P0A2E1:GLYA_SALTY Serine hydroxymethyltransferase - Salmonella typhimurium| Length = 417 Score = 300 bits (768), Expect = 2e-80 Identities = 171/406 (42%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDVVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLQPGDTVLGMNLAQ 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ ++G IDYD++ A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGID-ESGKIDYDEMAKLAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GL+AA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + G D + K+N AVFPS QGGP + IA A+ LK+ Sbjct: 237 GLILAKGG----------------DEELYKKLNSAVFPSAQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGT+NHL L DL LTGK + Sbjct: 281 EPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+RIG+PA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWM 386
>P0A2E2:GLYA_SALTI Serine hydroxymethyltransferase - Salmonella typhi| Length = 417 Score = 300 bits (768), Expect = 2e-80 Identities = 171/406 (42%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDVVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLQPGDTVLGMNLAQ 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ ++G IDYD++ A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGID-ESGKIDYDEMAKLAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GL+AA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + G D + K+N AVFPS QGGP + IA A+ LK+ Sbjct: 237 GLILAKGG----------------DEELYKKLNSAVFPSAQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGT+NHL L DL LTGK + Sbjct: 281 EPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+RIG+PA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWM 386
>Q5PII3:GLYA_SALPA Serine hydroxymethyltransferase - Salmonella paratyphi-a| Length = 417 Score = 300 bits (768), Expect = 2e-80 Identities = 171/406 (42%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDVVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLQPGDTVLGMNLAQ 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ ++G IDYD++ A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGID-ESGKIDYDEMAKLAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GL+AA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + G D + K+N AVFPS QGGP + IA A+ LK+ Sbjct: 237 GLILAKGG----------------DEELYKKLNSAVFPSAQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGT+NHL L DL LTGK + Sbjct: 281 EPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+RIG+PA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWM 386
>Q57LF7:GLYA_SALCH Serine hydroxymethyltransferase - Salmonella choleraesuis| Length = 417 Score = 300 bits (768), Expect = 2e-80 Identities = 171/406 (42%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDVVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLQPGDTVLGMNLAQ 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ ++G IDYD++ A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGID-ESGKIDYDEMAKLAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GL+AA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + G D + K+N AVFPS QGGP + IA A+ LK+ Sbjct: 237 GLILAKGG----------------DEELYKKLNSAVFPSAQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGT+NHL L DL LTGK + Sbjct: 281 EPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+RIG+PA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWM 386
>Q831F9:GLYA_ENTFA Serine hydroxymethyltransferase - Enterococcus faecalis| (Streptococcus faecalis) Length = 412 Score = 300 bits (768), Expect = 2e-80 Identities = 172/405 (42%), Positives = 237/405 (58%), Gaps = 2/405 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DPD+ + RE +RQ +ELIASEN V +AV+ A GS LTNKY+EG+PG RYYGG + I Sbjct: 7 DPDLWNAIAREEERQENNLELIASENVVSKAVMAAQGSILTNKYAEGYPGKRYYGGCEFI 66 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L RA FG A NVQ +S + AN A Y L+ P D I+G++ +GGH+ Sbjct: 67 DIVENLAIDRAKELFGAKFA----NVQAHSGSQANTAAYLSLVEPGDTILGMDLSAGGHL 122 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG S SG + F +SY V+P T IDYD + A + PK+++ G S+Y R Sbjct: 123 THG----SPVNFSGKTYNF--VSYGVDPSTEVIDYDVVRILAREHRPKLIVAGASAYSRT 176 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF R R IAD+ A LM DMAHI+GLVA+ +P Y D+VTSTTHK LRGPRGG+I Sbjct: 177 IDFKRFREIADEVDAKLMVDMAHIAGLVASGLHPNPVPYADIVTSTTHKTLRGPRGGLIL 236 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 N + K+N ++FP +QGGP + IA A K+ P + Sbjct: 237 ------------------TNSEELAKKVNSSIFPGIQGGPLEHVIAGKAAAFKEALDPSF 278 Query: 1543 KAYIQQVMKNAQALASALLRR-KCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHIS 1719 Y QQV+ NAQA+ + + RL++G TDNHL+L ++ FGL GK E + + +I+ Sbjct: 279 AEYSQQVIANAQAMTKVFNQAPEARLISGATDNHLLLIEVTGFGLNGKEAEAILDSVNIT 338 Query: 1720 INKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIR 1851 +NK I + G+RIGTPA+T+RG E+D +A +++ Sbjct: 339 VNKNSIPFEQLSPFKTSGIRIGTPAITSRGFKEEDAVEVAKLIVQ 383
>Q5GW07:GLYA_XANOR Serine hydroxymethyltransferase - Xanthomonas oryzae pv. oryzae| Length = 417 Score = 300 bits (767), Expect = 2e-80 Identities = 174/402 (43%), Positives = 242/402 (60%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP++ + E RQ +ELIASEN+ + V++A GS LTNKY+EG+PG RYYGG + Sbjct: 12 DPELAKAIAAEAGRQEDHVELIASENYCSQLVMEAQGSQLTNKYAEGYPGKRYYGGCAFV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E+L R F D A NVQP+S + AN AVY LL P D I+G+ GGH+ Sbjct: 72 DIAEQLAIDRIKQVFDADYA----NVQPHSGSQANQAVYLALLQPGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG K + + F ++ Y VN Q G IDYD+++ A + PK+++ G S+Y ++ Sbjct: 128 THG------AKANVSGKLFNAVQYGVNEQ-GLIDYDEVQRLATEHTPKMVVAGFSAYSQK 180 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 D+AR R IAD GA L DMAHI+GLVAA SP ++ VVTSTTHK LRGPRGGII Sbjct: 181 IDWARFRAIADSVGAYLFVDMAHIAGLVAAGVYPSPMEHAHVVTSTTHKTLRGPRGGIIV 240 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 +G S + + K+ VFP +QGGP + IAA A+ K+ P + Sbjct: 241 --------AKGAS--------EELQKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y QQV+KNAQA+A+ L+ R ++V+GGT+NHL+L D+ ++GK+ E HI++ Sbjct: 285 KTYQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + D S G+R+GTPA+TTRG E D +A+++ Sbjct: 345 NKNAVPNDPRSPFVTSGLRLGTPAITTRGYKEPDSIDLANWI 386
>Q2NZ83:GLYA_XANOM Serine hydroxymethyltransferase - Xanthomonas oryzae pv. oryzae| (strain MAFF 311018) Length = 417 Score = 300 bits (767), Expect = 2e-80 Identities = 174/402 (43%), Positives = 242/402 (60%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP++ + E RQ +ELIASEN+ + V++A GS LTNKY+EG+PG RYYGG + Sbjct: 12 DPELAKAIAAEAGRQEDHVELIASENYCSQLVMEAQGSQLTNKYAEGYPGKRYYGGCAFV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E+L R F D A NVQP+S + AN AVY LL P D I+G+ GGH+ Sbjct: 72 DIAEQLAIDRIKQVFDADYA----NVQPHSGSQANQAVYLALLQPGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG K + + F ++ Y VN Q G IDYD+++ A + PK+++ G S+Y ++ Sbjct: 128 THG------AKANVSGKLFNAVQYGVNEQ-GLIDYDEVQRLATEHTPKMVVAGFSAYSQK 180 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 D+AR R IAD GA L DMAHI+GLVAA SP ++ VVTSTTHK LRGPRGGII Sbjct: 181 IDWARFRAIADSVGAYLFVDMAHIAGLVAAGVYPSPMEHAHVVTSTTHKTLRGPRGGIIV 240 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 +G S + + K+ VFP +QGGP + IAA A+ K+ P + Sbjct: 241 --------AKGAS--------EELQKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y QQV+KNAQA+A+ L+ R ++V+GGT+NHL+L D+ ++GK+ E HI++ Sbjct: 285 KTYQQQVVKNAQAMANTLIARGYKIVSGGTENHLMLVDMIGRDVSGKDAEAALGKAHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + D S G+R+GTPA+TTRG E D +A+++ Sbjct: 345 NKNAVPNDPRSPFVTSGLRLGTPAITTRGYKEPDSIDLANWI 386
>Q31FS6:GLYA_THICR Serine hydroxymethyltransferase - Thiomicrospira crunogena (strain| XCL-2) Length = 423 Score = 300 bits (767), Expect = 2e-80 Identities = 172/411 (41%), Positives = 239/411 (58%), Gaps = 3/411 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N +A D + M E RQ IELIASEN+ V++A GS LTNKY+EG+P RY Sbjct: 5 NMTIAGYDDALADAMNAEAQRQEDHIELIASENYTSPRVMEAQGSVLTNKYAEGYPNKRY 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +H+D +E+L RA FG D A NVQP+S + AN VY LL P D ++G+ Sbjct: 65 YGGCEHVDVVEQLAIDRAKELFGADYA----NVQPHSGSQANAPVYMALLEPGDTVLGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG + VS + + ++ Y +NP+TG IDYD++E A + PK++I G Sbjct: 121 LAHGGHLTHGSH------VSFSGKMYNAVQYGLNPETGVIDYDEVERLAKEHKPKMIIAG 174 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y + D+ + R IAD GA LM DMAH++GLVAA E +P DV T+TTHK LRG Sbjct: 175 FSAYSQVVDWQKFREIADAVGAYLMVDMAHVAGLVAAGEYPNPVQIADVTTTTTHKTLRG 234 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PR G+I + ++ + E K+N A+FP QGGP + IAA A+ K Sbjct: 235 PRSGLILAK-----------------SNPEIEKKLNSAIFPGAQGGPLMHVIAAKAVAFK 277 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + PE+K Y +QV NA+A+A + R +V+ GT+NHL L GLTGK + Sbjct: 278 EAMEPEFKTYAKQVKVNAKAMADVFMARGFDVVSKGTENHLFLVSFIEQGLTGKLVDAAL 337 Query: 1702 ELCHISINKTPIYGDNGSISP---GGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI+INK + N +SP G+R+GT A TTRG E+D + +A ++ Sbjct: 338 GEAHITINKNSV--PNDPMSPFVTSGIRVGTAASTTRGFTEEDSKNLASWM 386
>Q3YZ04:GLYA_SHISS Serine hydroxymethyltransferase - Shigella sonnei (strain Ss046)| Length = 417 Score = 299 bits (766), Expect = 3e-80 Identities = 175/406 (43%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDIVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ TG+IDY LE +A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GLVAA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I +GGS + K+N AVFP QGGP + IA A+ LK+ Sbjct: 237 GLIL--------AKGGS--------EELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGTDNHL L DL LTGK + Sbjct: 281 EPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+R+GTPA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWM 386
>P0A827:GLYA_SHIFL Serine hydroxymethyltransferase - Shigella flexneri| Length = 417 Score = 299 bits (766), Expect = 3e-80 Identities = 175/406 (43%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDIVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ TG+IDY LE +A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GLVAA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I +GGS + K+N AVFP QGGP + IA A+ LK+ Sbjct: 237 GLIL--------AKGGS--------EELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGTDNHL L DL LTGK + Sbjct: 281 EPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+R+GTPA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWM 386
>Q31XT6:GLYA_SHIBS Serine hydroxymethyltransferase - Shigella boydii serotype 4 (strain| Sb227) Length = 417 Score = 299 bits (766), Expect = 3e-80 Identities = 175/406 (43%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDIVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ TG+IDY LE +A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GLVAA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I +GGS + K+N AVFP QGGP + IA A+ LK+ Sbjct: 237 GLIL--------AKGGS--------EELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGTDNHL L DL LTGK + Sbjct: 281 EPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+R+GTPA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWM 386
>P0A825:GLYA_ECOLI Serine hydroxymethyltransferase - Escherichia coli| Length = 417 Score = 299 bits (766), Expect = 3e-80 Identities = 175/406 (43%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDIVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ TG+IDY LE +A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GLVAA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I +GGS + K+N AVFP QGGP + IA A+ LK+ Sbjct: 237 GLIL--------AKGGS--------EELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGTDNHL L DL LTGK + Sbjct: 281 EPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+R+GTPA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWM 386
>P0A826:GLYA_ECOL6 Serine hydroxymethyltransferase - Escherichia coli O6| Length = 417 Score = 299 bits (766), Expect = 3e-80 Identities = 175/406 (43%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDIVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ TG+IDY LE +A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GLVAA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I +GGS + K+N AVFP QGGP + IA A+ LK+ Sbjct: 237 GLIL--------AKGGS--------EELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGTDNHL L DL LTGK + Sbjct: 281 EPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+R+GTPA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWM 386
>Q391K1:GLYA2_BURS3 Serine hydroxymethyltransferase 2 - Burkholderia sp. (strain 383)| (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) Length = 415 Score = 299 bits (766), Expect = 3e-80 Identities = 169/426 (39%), Positives = 251/426 (58%), Gaps = 4/426 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A DP+++A +E+E RQ IELIASEN+ AV+ A GS LTNKY+EG+PG RYYGG Sbjct: 9 VANVDPELYAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG + A NVQP S + AN V+ +L P D IMG+ Sbjct: 69 CEYVDVVEQLAIDRVKQLFGAEAA----NVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 124 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F +SY +N IDY+ E A + PK+++ G S+ Sbjct: 125 GGHLTHG------SPVNMSGKWFNVVSYGLNENED-IDYEAAEQLAQEHKPKLIVAGASA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 + + DF R+ IA GA LM DMAH +GL+AA +P + D VT+TTHK+LRGPRG Sbjct: 178 FSLKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++E IN A+FP +QGGP + IA A+ K+ Sbjct: 238 GVILMKA-------------------EYEKPINSAIFPGIQGGPLMHVIAGKAVAFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 +PE+KAY ++V++NA+ LA L++R R+V+G T++H++L DLR +TGK E Sbjct: 279 SPEFKAYQEKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGAA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL---IRATQIAGSVL 1878 HI++NK I D GVR+G+PAMTTRG + E++ + + + A + A ++ Sbjct: 339 HITVNKNAIPNDPEKPFVTSGVRLGSPAMTTRGFGVKEAEIVGNLIADVLEAPEDAATLE 398 Query: 1879 KQHGKV 1896 + G+V Sbjct: 399 RVRGQV 404
>Q8U7Y5:GLYA2_AGRT5 Serine hydroxymethyltransferase 2 - Agrobacterium tumefaciens (strain| C58 / ATCC 33970) Length = 422 Score = 299 bits (766), Expect = 3e-80 Identities = 180/424 (42%), Positives = 242/424 (57%), Gaps = 2/424 (0%) Frame = +1 Query: 640 ADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQH 819 +D + + E DRQ IELIASEN V VL A GS LTNKY+EG+PG RYYGG + Sbjct: 11 SDTVIADAIAEELDRQKTQIELIASENIVSADVLAAQGSVLTNKYAEGYPGKRYYGGCEF 70 Query: 820 IDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGH 999 +D +E++ R FG + A NVQP+S AN AV+ LL P DRIMGL GGH Sbjct: 71 VDKVEQVAIDRLKQLFGAEFA----NVQPHSGAQANQAVFLALLQPGDRIMGLSLAHGGH 126 Query: 1000 VSHGY-YTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYP 1176 ++HG T SGK +F+ +SY+V+P+T ID +K+ ++A++ PK+++ G S+YP Sbjct: 127 LTHGSPVTMSGK-------WFDVVSYEVDPETHLIDMEKVREKALETKPKLIVAGASAYP 179 Query: 1177 REWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGI 1356 R+ DFA R IAD+ GA LM DMAH +GL+A + + V TSTTHK LRGPRGG+ Sbjct: 180 RQIDFAGFREIADEVGAYLMVDMAHYAGLIAGGHYPNAVPHAHVTTSTTHKTLRGPRGGV 239 Query: 1357 IFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATP 1536 I ND D K+N AVFP QGGP + IAA A+ + P Sbjct: 240 IL------------------TNDADLAKKLNSAVFPGNQGGPLMHVIAAKAVAFGEALRP 281 Query: 1537 EYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHI 1716 E+ Y QV+ NAQALA L++ +V+GGTD+H+VL DLR G+TGK E E + Sbjct: 282 EFSDYAGQVIANAQALAKVLIQGGLGIVSGGTDSHMVLVDLRPKGVTGKIAEIALERAGL 341 Query: 1717 SINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQHGK 1893 + NK I D G+R+G+ A TTRG +FE I ++R + + Sbjct: 342 TCNKNSIPNDPEKPFVTSGIRLGSSAGTTRGFGVLEFEKIGALILRVIDALATNAEGDSA 401 Query: 1894 VQKE 1905 V+ E Sbjct: 402 VEAE 405
>Q6N693:GLYA1_RHOPA Serine hydroxymethyltransferase 1 - Rhodopseudomonas palustris| Length = 432 Score = 299 bits (766), Expect = 3e-80 Identities = 176/406 (43%), Positives = 230/406 (56%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L +ADP++ A + E RQ +ELIASEN V RAVL+A GS +TNKY+EG+PG RYYGG Sbjct: 18 LEQADPEIAAAIRGELGRQRHEVELIASENIVSRAVLEAQGSVMTNKYAEGYPGNRYYGG 77 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E L RA FG + A NVQP S + N AV+ LL P D MGL+ + Sbjct: 78 CEFVDVAENLAIDRAKKLFGANFA----NVQPNSGSQMNQAVFLALLQPGDTFMGLDLAA 133 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F+ + Y V + ID D + A + PK++I GGS+ Sbjct: 134 GGHLTHG------APVNMSGKWFKPVHYTVRREDQMIDMDAVAKLAEEAKPKLIIAGGSA 187 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR WDF R R IAD GA M DMAH +GLVA SP + V T+TTHK+LRGPRG Sbjct: 188 YPRAWDFKRFREIADSVGAYFMVDMAHFAGLVAGGVHASPVPHAHVTTTTTHKSLRGPRG 247 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ND K N A+FP LQGGP + IAA A+ K+ Sbjct: 248 GLIL------------------TNDEALAKKFNSAIFPGLQGGPLMHVIAAKAVAFKEAL 289 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P++K Y + V++NA+ALA L LV+GGTDNHL+L DLR GL G EK Sbjct: 290 QPDFKVYTKNVVENAKALAETLRSAGFDLVSGGTDNHLMLVDLRPKGLKGNVSEKALVRA 349 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + G+R+GTPA TTRG +F+ + + Sbjct: 350 GITCNKNGIPFDPEKPFVTSGLRLGTPAATTRGFGVAEFQQVGHLI 395
>Q5V3D7:GLYA_HALMA Serine hydroxymethyltransferase - Haloarcula marismortui| (Halobacterium marismortui) Length = 415 Score = 299 bits (765), Expect = 4e-80 Identities = 174/412 (42%), Positives = 235/412 (57%), Gaps = 3/412 (0%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 + + EADP V +E ER RQ + +IASEN V AV++A S LTNKY+EG+PG RYY Sbjct: 4 ETVREADPAVADALEGERGRQNDTLAMIASENHVSEAVMEAQSSELTNKYAEGYPGERYY 63 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 GG ++ D +E L RA +G D VNVQP+S + AN+ VY G+L P D+I+ L+ Sbjct: 64 GGCEYADDVEELAIDRAKELWGADH----VNVQPHSGSQANMGVYLGVLEPGDKILSLDL 119 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 GGH+SHG+ + A +E YKV+ +TGY+DY+ L D A +F P I++ G Sbjct: 120 THGGHLSHGH------PANFAGQVYEVEQYKVDEETGYVDYEGLHDHAEEFEPDIIVSGY 173 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S+YPRE DF R++ AD A + D+AHI+GLVAA SP D VT +THK +R Sbjct: 174 SAYPREVDFERIQEAADAVDAYHLADIAHITGLVAAGVHESPVGVADFVTGSTHKTIRAG 233 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 RGGII D ++ D I+ AVFP QGGP +++A A+ + Sbjct: 234 RGGIIMC-------------------DEEYADDIDAAVFPGSQGGPLMHNVAGKAVGFGE 274 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTF--GLTGKNFEKV 1698 PE++ Y QQ + NA AL LV+GGTDNHLVL DLR TGK E+ Sbjct: 275 ALAPEFEQYAQQTVDNAIALGEQFKEHGLSLVSGGTDNHLVLIDLRPSHPDTTGKEVEEA 334 Query: 1699 CELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIR 1851 E I +N + G+ S +P G+R GTPA+TTRG ED +AD + + Sbjct: 335 LEEAGIVLNANTVPGETRSAFNPSGIRAGTPALTTRGFDEDACREVADLIYK 386
>Q8XA55:GLYA_ECO57 Serine hydroxymethyltransferase - Escherichia coli O157:H7| Length = 417 Score = 299 bits (765), Expect = 4e-80 Identities = 175/406 (43%), Positives = 242/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDIVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ TG+IDY LE +A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GLVAA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I +GGS + K+N AVFP QGGP + IA A+ LK+ Sbjct: 237 GLIL--------AKGGS--------EELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGTDNHL L DL LTGK + Sbjct: 281 EPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+R+GTPA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEVEAKELAGWM 386
>Q8Y1G1:GLYA1_RALSO Serine hydroxymethyltransferase 1 - Ralstonia solanacearum| (Pseudomonas solanacearum) Length = 415 Score = 299 bits (765), Expect = 4e-80 Identities = 171/405 (42%), Positives = 238/405 (58%), Gaps = 2/405 (0%) Frame = +1 Query: 637 EADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQ 816 + DP+V A +++E RQ IELIASEN+ AV+ A GS LTNKY+EG+PG RYYGG + Sbjct: 11 QIDPEVFAAIQQENQRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCE 70 Query: 817 HIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGG 996 ++D +E+L R FG + A NVQP S + AN V+ +L P D IMG+ GG Sbjct: 71 YVDVVEQLAIDRVKQLFGAEAA----NVQPNSGSQANQGVFFAMLKPGDTIMGMSLAEGG 126 Query: 997 HVSHGY-YTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSY 1173 H++HG SGK +F +SY +N Q IDYD LE A + PK++I G S++ Sbjct: 127 HLTHGMALNMSGK-------WFNVVSYGLNAQED-IDYDALEALAQEKKPKLIIAGASAF 178 Query: 1174 PREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGG 1353 DF R+ +A GA M DMAH +GL+AA +P + D VT+TTHK+LRGPRGG Sbjct: 179 ALRIDFERIAKVAKAVGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 238 Query: 1354 IIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVAT 1533 +I + + E IN A+FP +QGGP + IA A+ K+ + Sbjct: 239 VILMKA-------------------EHEKAINSAIFPGIQGGPLMHVIAGKAVAFKEAQS 279 Query: 1534 PEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCH 1713 P +KAY +QV+KNA+A+A L+ R R+V+G T++H++L DLR +TGK EKV H Sbjct: 280 PTFKAYQEQVVKNARAMAETLMARGLRIVSGRTESHVMLVDLRAKSITGKEAEKVLGDAH 339 Query: 1714 ISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I++NK I D G+R+G+PAMTTRG E + +A + Sbjct: 340 ITVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFKEGEAVKVAHLI 384
>Q4FLT4:GLYA_PELUB Serine hydroxymethyltransferase - Pelagibacter ubique| Length = 436 Score = 298 bits (764), Expect = 5e-80 Identities = 173/433 (39%), Positives = 241/433 (55%), Gaps = 1/433 (0%) Frame = +1 Query: 610 RAWGNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHP 789 +++ + L+ DP++H + E RQ + IELIASEN V +AVL+A GS LTNKY+EG+P Sbjct: 13 KSFFDDSLSVTDPELHKAISDELKRQQQHIELIASENIVSQAVLEAQGSVLTNKYAEGYP 72 Query: 790 GARYYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRI 969 G RYY G +H+D E L +R F C N QP+S AN AV+ LL P D Sbjct: 73 GKRYYNGCEHVDVAENLAIERLKKIFD----CKFANAQPHSGAQANGAVFLALLNPGDTF 128 Query: 970 MGLEPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKI 1149 MG+ SGGH++HG K+S + +F + Y V+ ++ IDYD +E A++ PK+ Sbjct: 129 MGMSLNSGGHITHGL------KISMSGKWFNPIGYDVDKESELIDYDNVEKLALEHKPKL 182 Query: 1150 LICGGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHK 1329 +ICGGS+Y R DF R R IADK GA LM DMAH SGLVA K +P ++ VVTSTTHK Sbjct: 183 IICGGSAYSRVIDFKRFREIADKVGAYLMVDMAHFSGLVAGKGYPNPCEHAHVVTSTTHK 242 Query: 1330 NLRGPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALA 1509 R RGGII N D K N AVFP QGGP + IA A Sbjct: 243 VFRSARGGIIL------------------TNHEDLAKKFNTAVFPGYQGGPLMHVIAGKA 284 Query: 1510 ITLKQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNF 1689 + P++K YI+ V+ NA+ L+ L ++ +GGTD HL+L DLR F + G Sbjct: 285 AGFLEALRPDFKDYIKSVLANAKILSETLKNNGFKIYSGGTDTHLMLVDLRPFNVKGNAA 344 Query: 1690 EKVCELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIA 1866 + +I+ NK I + + G+R+GT A TTRG +FE + + + + + Sbjct: 345 AESLSNANITCNKNGIPFDSEKPMITSGIRLGTQAATTRGFGLKEFEKVGELITKVVKGL 404 Query: 1867 GSVLKQHGKVQKE 1905 + +GK+++E Sbjct: 405 SENPEDNGKIEEE 417
>Q3J9K8:GLYA_NITOC Serine hydroxymethyltransferase - Nitrosococcus oceani (strain ATCC| 19707 / NCIMB 11848) Length = 417 Score = 298 bits (764), Expect = 5e-80 Identities = 181/455 (39%), Positives = 253/455 (55%), Gaps = 1/455 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A D ++ + E RQ IELIASEN+V VL+A GS LTNKY+EG+PG RYYGG Sbjct: 8 IASYDEELETALTNEARRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D ERL +RA F D A NVQP+S + AN A LL P D +MGL Sbjct: 68 CEYVDVAERLAIERAKILFEADYA----NVQPHSGSQANAAACLALLAPGDTLMGLSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG KV+ + F ++ + VN TG IDYD++E A PK++I G ++ Sbjct: 124 GGHLTHG------AKVNFSGQIFNAVQFGVNADTGLIDYDEVEQLAKAHRPKLIIAGFTA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R D+ R R IAD GA L+ D+AH++G++AA +P DV TSTTHK LRGPR Sbjct: 178 YSRIVDWQRFRAIADGVGAYLLADIAHLAGMIAAGIYPNPVQIADVTTSTTHKTLRGPRS 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + + E K+N VFP +QGGP + +AA A+ K+ Sbjct: 238 GLILAKANP-----------------EIEKKLNSKVFPGIQGGPLMHVVAAKAVAFKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P +K Y +QV++NAQA+A A+ R ++V+GGTD+HL L DL GLTGK + Sbjct: 281 EPAFKDYQRQVIRNAQAMAEAIQSRGYKIVSGGTDSHLFLVDLVAKGLTGKAADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 +I++NK + D S G+RIG+PAMTTRG E + ++AG V Sbjct: 341 NITVNKNTVPNDPQSPFVTSGIRIGSPAMTTRGFKEAEI----------CELAGWVC--- 387 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAMPG 1992 + L +EN I + +V A ++F + G Sbjct: 388 -----DVLDDIENETVIADTKEKVLALCARFPVYG 417
>Q9CHW7:GLYA_LACLA Serine hydroxymethyltransferase - Lactococcus lactis subsp. lactis| (Streptococcus lactis) Length = 415 Score = 298 bits (764), Expect = 5e-80 Identities = 172/406 (42%), Positives = 236/406 (58%), Gaps = 2/406 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP++ A + E RQ + IELIASEN V +AV+ A GS LTNKY+EG+PG RYYGG + + Sbjct: 12 DPELWAAIHAEEIRQQQNIELIASENIVSKAVMAAQGSVLTNKYAEGYPGKRYYGGTEAV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG A NVQP+S + AN A Y L+ P D ++G++ +GGH+ Sbjct: 72 DVVENLAIERAKELFGAKFA----NVQPHSGSQANAAAYMALIQPGDTVLGMDLNAGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG + SG + F + Y VN +T +DYD++ A PK+++ G S+Y R Sbjct: 128 THG----ASVNFSGKTYHF--VPYGVNSETELLDYDEILKIAKQVQPKLIVAGASAYSRL 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFA+ R IAD GA LM DMAHI+GLVA +P Y DVVT+TTHK LRGPRGG+I Sbjct: 182 IDFAKFREIADSVGAKLMVDMAHIAGLVATGAHPNPLPYADVVTTTTHKTLRGPRGGMIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 ND KIN A+FP QGGP + IAA A+ K+ PE+ Sbjct: 242 ------------------TNDEALAKKINSAIFPGTQGGPLEHVIAAKAVAFKEALDPEF 283 Query: 1543 KAYIQQVMKNAQALASALLR-RKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHIS 1719 YI+QV+KN QA+A + RL+ GG+DNHL+ + G+ GK + + + HI+ Sbjct: 284 TTYIEQVIKNTQAMAEEFAKVEGLRLIAGGSDNHLLNLKVLDLGINGKEAQDLLDSVHIT 343 Query: 1720 INKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 +NK I + S GVRIG A+T+RG E + + +A + A Sbjct: 344 LNKEAIPDETLSPFKTSGVRIGAAAITSRGFKEVEAKKVAQLVSEA 389
>Q5M4W1:GLYA_STRT2 Serine hydroxymethyltransferase - Streptococcus thermophilus (strain| ATCC BAA-250 / LMG 18311) Length = 416 Score = 298 bits (763), Expect = 7e-80 Identities = 171/408 (41%), Positives = 242/408 (59%), Gaps = 2/408 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP++ ++ E +RQ IELIASEN V +AV+ A G+ LTNKY+EG+PG RYYGG I Sbjct: 12 DPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKYAEGYPGKRYYGGTAVI 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG+ A NVQP+S + AN AVY L+ P D +MG++ +GGH+ Sbjct: 72 DVVETLAIERAKKLFGVKFA----NVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG VS + + +SY V+ ++ +DYD + +A + PK+++ G S+Y R Sbjct: 128 THG------APVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYSRI 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFA+ R IAD GA LM DMAHI+GLVA+ SP Y V T+TTHK LRGPRGG+I Sbjct: 182 IDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 +D D K+N AVFP LQGGP + IAA A+ LK+ P + Sbjct: 242 ------------------TDDEDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAF 283 Query: 1543 KAYIQQVMKNAQALASALLRR-KCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHIS 1719 K Y + V+KNA A+A + R+++GGT+NHL L D+ GK + V E +I+ Sbjct: 284 KEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNIT 343 Query: 1720 INKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 +NK I Y G+R+G+PA+T+RG E + IA++++ A + Sbjct: 344 LNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALE 391
>Q7W400:GLYA2_BORPA Serine hydroxymethyltransferase 2 - Bordetella parapertussis| Length = 415 Score = 298 bits (763), Expect = 7e-80 Identities = 166/409 (40%), Positives = 240/409 (58%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L + DPDV A +++E RQ + IELIASEN+ AV+ A G+ LTNKY+EG+PG RY Sbjct: 5 NLTLDQVDPDVWAAIQKEDVRQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRY 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +++D +E+L R FG + A NVQP S + AN VY +L P D ++G+ Sbjct: 65 YGGCEYVDVVEQLAIDRLKQIFGAEAA----NVQPNSGSQANQGVYMAVLKPGDTVLGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG V+ + + + Y ++ +DY ++E + PK+++ G Sbjct: 121 LAEGGHLTHG------ASVNASGKLYNFVPYGLDADE-VLDYAQVERLTKEHKPKLIVAG 173 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y DF RM IA GA+ M D+AH +GLVA +P + D VTSTTHK+LRG Sbjct: 174 ASAYALHIDFERMARIAHDNGALFMVDIAHYAGLVAGGAYPNPVPHADFVTSTTHKSLRG 233 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I + + E +N A+FP +QGGP + IAA A+ K Sbjct: 234 PRGGVIMMKA-------------------EVEKAVNSAIFPGIQGGPLMHVIAAKAVAFK 274 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + +PE++ Y QQV+KNA+ LA L++R R+V+G T++H++L DLR G+TGK E V Sbjct: 275 EALSPEFQDYAQQVVKNAKVLADTLVKRGLRIVSGRTESHVMLVDLRPKGITGKEAEAVL 334 Query: 1702 ELCHISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+R+GTPAMTTRG E + E+ A+ + Sbjct: 335 GQAHITVNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTANLI 383
>Q32D21:GLYA_SHIDS Serine hydroxymethyltransferase - Shigella dysenteriae serotype 1| (strain Sd197) Length = 417 Score = 298 bits (762), Expect = 9e-80 Identities = 174/406 (42%), Positives = 241/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E+ RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN VYT LL P D ++G+ Sbjct: 68 CEYVDIVEQLAIDRAKELFGADYA----NVQPHSGSQANFTVYTALLEPGDTVLGMNLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ TG+IDY LE +A + PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GLVAA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I +GGS + K+N AVFP QGGP + IA A+ LK+ Sbjct: 237 GLIL--------AKGGS--------EELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R ++V+GGTDNHL L DL LTGK + Sbjct: 281 EPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+R+GTPA+T RG E + + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWM 386
>Q4FUZ8:GLYA_PSYAR Serine hydroxymethyltransferase - Psychrobacter arcticum| Length = 418 Score = 298 bits (762), Expect = 9e-80 Identities = 170/406 (41%), Positives = 241/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + DP + M E RQ IELIASEN+ +AV++A G+ LTNKY+EG+PG RYYGG Sbjct: 7 IKDFDPVLAKAMAAESVRQENHIELIASENYCSQAVMEAQGTDLTNKYAEGYPGKRYYGG 66 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E+L RA FG + VNVQP+S + AN AV+ LL ND ++G+ + Sbjct: 67 CEHVDVVEQLAIDRAKELFGAEY----VNVQPHSGSQANSAVFLALLEANDTVLGMSLDA 122 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG + ++ + + + ++ Y + TG IDYD++E A + PK++I G S+ Sbjct: 123 GGHLTHGAH------INFSGLNYNAVQYGLVEGTGLIDYDQVESLAKEHKPKMIIAGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + D+AR R IAD+ GA L+ DMAH++GL+A SP + DVVT+TTHK LRGPR Sbjct: 177 YSQVVDWARFREIADEVGAYLLVDMAHVAGLIAGGVYPSPVPFADVVTTTTHKTLRGPRS 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D K+N AVFP QGGP + IAA AI K+ Sbjct: 237 GMILAR------------------DEKLAKKLNSAVFPGNQGGPLMHVIAAKAICFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 +K Y QQV+KNAQA+A + R +++GGT+NHL+L L +TGK +K Sbjct: 279 ENNFKTYQQQVVKNAQAMAKVIQERGYEIISGGTENHLMLISLVKQEMTGKEADKWLGDA 338 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK + D S G+RIGTPA+TTRG E +A ++ Sbjct: 339 HITVNKNAVPNDPKSPFVTSGIRIGTPAITTRGFNEAQAGALAGWI 384
>Q8G1F1:GLYA_BRUSU Serine hydroxymethyltransferase - Brucella suis| Length = 438 Score = 298 bits (762), Expect = 9e-80 Identities = 177/409 (43%), Positives = 232/409 (56%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L + DP++ + E RQ IELIASEN V RAVL+A GS LTNKY+EG+PG RY Sbjct: 17 NASLEDIDPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRY 76 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG Q++D +E L +RA F + A NVQP S + N AV+ LL P D MGL+ Sbjct: 77 YGGCQYVDVVEELAIERAKKLFSAEFA----NVQPNSGSQMNQAVFLALLQPGDTFMGLD 132 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 SGGH++HG V+ + +F +SY V +D D++ A + PK+++ G Sbjct: 133 LNSGGHLTHG------SPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAG 186 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 G++Y R WD+ R R IAD+ GA LM DMAHI+GLVA + SP + V T+TTHK+LRG Sbjct: 187 GTAYSRIWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRG 246 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I ND D KIN AVFP LQGGP + IA A+ Sbjct: 247 PRGGMIL------------------TNDADIAKKINSAVFPGLQGGPLMHVIAGKAVAFA 288 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + E+K Y + V+ NA+ALA L +V+GGTDNHL+L DLR TGK E Sbjct: 289 EALKLEFKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAAL 348 Query: 1702 ELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK I + GVR+GTPA TTRG +F+ I + Sbjct: 349 GRANITCNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFGVAEFKEIGSLI 397
>Q6G3L3:GLYA_BARHE Serine hydroxymethyltransferase - Bartonella henselae (Rochalimaea| henselae) Length = 437 Score = 298 bits (762), Expect = 9e-80 Identities = 180/409 (44%), Positives = 236/409 (57%), Gaps = 1/409 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N L D + + E +RQ IELIASEN V RAVL+A GS LTNKY+EG+PG RY Sbjct: 14 NDNLQTVDVAIFDAIRGEFERQQHEIELIASENIVSRAVLEAQGSVLTNKYAEGYPGKRY 73 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG Q +D IE L +RA FG D A NVQ S + N AV+ LL P D MGL+ Sbjct: 74 YGGCQFVDVIENLAIERAKKLFGADFA----NVQANSGSQMNQAVFLALLKPGDTFMGLD 129 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 SGGH++HG S +SG +F+S+SY V + +D + +E A + PK++I G Sbjct: 130 LNSGGHLTHG----SSVNMSGK--WFKSISYGVRKEDQLLDMEAVERLAKEHKPKLIIAG 183 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 GS+Y R WD+ + R IAD+ GA L+ DM+HI+GLVA SP + +VT+TTHK+LRG Sbjct: 184 GSAYSRLWDWKKFREIADEIGAYLLVDMSHIAGLVAGGVHPSPVPHAHIVTTTTHKSLRG 243 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I ND KIN A+FP LQGGP + IAA A+ + Sbjct: 244 PRGGLIL------------------TNDEILAKKINSAIFPGLQGGPLMHVIAAKAVAFE 285 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + P +K Y V+ NA+ LA L +V+GGTDNHL+L DLR+ +TGK E Sbjct: 286 EALQPVFKDYSANVVANAKTLAKTLQSNGFDIVSGGTDNHLLLVDLRSKKVTGKCAELAL 345 Query: 1702 ELCHISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI+ NK I D G+R+G+PA TTRG E++F IA + Sbjct: 346 GRAHITCNKNSIPFDLETPFITSGIRLGSPAATTRGFAENEFIEIAHMI 394
>Q5M0B4:GLYA_STRT1 Serine hydroxymethyltransferase - Streptococcus thermophilus (strain| CNRZ 1066) Length = 416 Score = 297 bits (761), Expect = 1e-79 Identities = 171/408 (41%), Positives = 241/408 (59%), Gaps = 2/408 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP++ ++ E +RQ IELIASEN V +AV+ A G+ LTNKY+EG+PG RYYGG I Sbjct: 12 DPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKYAEGYPGKRYYGGTAVI 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG A NVQP+S + AN AVY L+ P D +MG++ +GGH+ Sbjct: 72 DVVETLAIERAKKLFGAKFA----NVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG VS + + +SY V+ ++ +DYD + +A + PK+++ G S+Y R Sbjct: 128 THG------APVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYSRI 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFA+ R IAD GA LM DMAHI+GLVA+ SP Y V T+TTHK LRGPRGG+I Sbjct: 182 IDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 +D D K+N AVFP LQGGP + IAA A+ LK+ P + Sbjct: 242 ------------------TDDEDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAF 283 Query: 1543 KAYIQQVMKNAQALASALLRR-KCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHIS 1719 K Y + V+KNA A+A + R+++GGT+NHL L D+ GK + V E +I+ Sbjct: 284 KEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNIT 343 Query: 1720 INKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQ 1860 +NK I Y G+R+G+PA+T+RG E + IA++++ A + Sbjct: 344 LNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALE 391
>Q2NS25:GLYA_SODGM Serine hydroxymethyltransferase - Sodalis glossinidius (strain| morsitans) Length = 417 Score = 297 bits (761), Expect = 1e-79 Identities = 175/406 (43%), Positives = 239/406 (58%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D ++ ME+E RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDAELWHAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D ++G+ Sbjct: 68 CEYVDVVEQLAIDRAKALFGADYA----NVQPHSGSQANFAVYTTLLQPGDTVLGMNLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + Y ++ ++G+IDYD+L + A PK++I G S+ Sbjct: 124 GGHLTHG------SPVNFSGKLYNIVPYGID-ESGHIDYDQLAELAKTHQPKMIIGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+ARMR IAD GA L DMAH++GL+AA +P + VVT+TTHK L GPRG Sbjct: 177 YSGVVDWARMRQIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I +GGS + K+N AVFP QGGP + IAA A+ LK+ Sbjct: 237 GLIL--------AKGGS--------EELYKKLNSAVFPGAQGGPLMHVIAAKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P +K Y QQV KNA+A+ L R +V+G TDNHL L DL LTGK + Sbjct: 281 EPAFKTYQQQVAKNAKAMVEVFLSRGFNVVSGATDNHLFLLDLVDKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+RIGTPA+T RG E D +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGMRIGTPAVTRRGFTEADVRDLAGWM 386
>Q82UP9:GLYA_NITEU Serine hydroxymethyltransferase - Nitrosomonas europaea| Length = 416 Score = 297 bits (761), Expect = 1e-79 Identities = 172/406 (42%), Positives = 236/406 (58%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + DPD+ ++ E RQ IELIASEN+ AVL A G+ LTNKY+EG+PG RYYGG Sbjct: 8 IEQVDPDLWQAIKGEVQRQEDHIELIASENYASPAVLQAQGTVLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R F + VNVQP+S + AN AVY L P D ++G+ Sbjct: 68 CRYVDIVEQLAIDRLRNLFNAEY----VNVQPHSGSQANAAVYLSALKPGDTLLGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S +SG F S+SY +NP+T IDY +LE A + P++++ G SS Sbjct: 124 GGHLTHG----SAVNMSGK--IFNSISYGLNPETEEIDYAELERLAHEHKPRMIVAGASS 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R D+ R IAD GA L DMAH +GL+AA +P D VTSTTHK LRGPRG Sbjct: 178 YARVIDWKAFRQIADNVGAYLFVDMAHYAGLIAAGYYPNPVGIADFVTSTTHKTLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + + E +N AVFP QGGP + IAA A+ K+ + Sbjct: 238 GVIMAKP-------------------EHEKALNSAVFPQTQGGPLMHVIAAKAVAFKEAS 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 + +K Y +QV++NA+ +A L +R R+V+G TD H+ L DLR LTG+ E E Sbjct: 279 SQAFKDYQKQVIENARVMARVLQQRGLRIVSGRTDCHMFLVDLRAKNLTGREAESALEAA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+RIGTPA+TTRG E + E +A+ + Sbjct: 339 HITVNKNAIPNDPQKPFVTSGIRIGTPAITTRGFKEPESEELANLV 384
>Q9XB01:GLYA_NEIGO Serine hydroxymethyltransferase - Neisseria gonorrhoeae| Length = 416 Score = 297 bits (761), Expect = 1e-79 Identities = 169/406 (41%), Positives = 243/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DPD+ A + +E RQ +ELIASEN+V AV++A GS LTNKY+EG+P RYYGG Sbjct: 8 LAQYDPDLAAAIAQEDRRQQDHVELIASENYVSCAVMEAQGSQLTNKYAEGYPAKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG A NVQP+S + AN AVY +L P D I+G+ Sbjct: 68 CEYVDIVEQLAIDRVKELFGAAYA----NVQPHSGSQANQAVYASVLKPGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG + +SG + +++Y ++ + +DY ++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG----ASVNISGK--LYNAVTYGLD-ENEVLDYAEVERLALEHKPKMIVAGASA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + D+A+ R IADK GA L DMAH +GLVA E +P +CD VT+TTHK LRGPRG Sbjct: 177 YALQIDWAKFREIADKVGAYLFVDMAHYAGLVAGGEYPNPVPFCDFVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D E +N ++FPSLQGGP + IAA A+ K+ Sbjct: 237 GVILCR------------------DNTHEKALNSSIFPSLQGGPLMHVIAAKAVAFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y +QV NA +A L++R R+V+G T++H+ L DL+ +TGK E Sbjct: 279 QPEFKQYAKQVKINAAVMAEELVKRGLRIVSGRTESHVFLVDLQPMKITGKAAEAALGKA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+RIG+ AMTTRG E D V+++ + Sbjct: 339 HITVNKNAIPNDPEKPFVTSGIRIGSAAMTTRGFNETDARVLSNLV 384
>Q5F8C0:GLYA_NEIG1 Serine hydroxymethyltransferase - Neisseria gonorrhoeae (strain ATCC| 700825 / FA 1090) Length = 416 Score = 297 bits (761), Expect = 1e-79 Identities = 169/406 (41%), Positives = 243/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DPD+ A + +E RQ +ELIASEN+V AV++A GS LTNKY+EG+P RYYGG Sbjct: 8 LAQYDPDLAAAIAQEDRRQQDHVELIASENYVSCAVMEAQGSQLTNKYAEGYPAKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG A NVQP+S + AN AVY +L P D I+G+ Sbjct: 68 CEYVDIVEQLAIDRVKELFGAAYA----NVQPHSGSQANQAVYASVLKPGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG + +SG + +++Y ++ + +DY ++E A++ PK+++ G S+ Sbjct: 124 GGHLTHG----ASVNISGK--LYNAVTYGLD-ENEVLDYAEVERLALEHKPKMIVAGASA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + D+A+ R IADK GA L DMAH +GLVA E +P +CD VT+TTHK LRGPRG Sbjct: 177 YALQIDWAKFREIADKVGAYLFVDMAHYAGLVAGGEYPNPVPFCDFVTTTTHKTLRGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I R D E +N ++FPSLQGGP + IAA A+ K+ Sbjct: 237 GVILCR------------------DNTHEKALNSSIFPSLQGGPLMHVIAAKAVAFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y +QV NA +A L++R R+V+G T++H+ L DL+ +TGK E Sbjct: 279 QPEFKQYAKQVKINAAVMAEELVKRGLRIVSGRTESHVFLVDLQPMKITGKAAEAALGKA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+RIG+ AMTTRG E D V+++ + Sbjct: 339 HITVNKNAIPNDPEKPFVTSGIRIGSAAMTTRGFNETDARVLSNLV 384
>Q601P7:GLYA_MYCH2 Serine hydroxymethyltransferase - Mycoplasma hyopneumoniae (strain| 232) Length = 418 Score = 297 bits (761), Expect = 1e-79 Identities = 175/427 (40%), Positives = 251/427 (58%), Gaps = 7/427 (1%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + L+ E RQ IELIASEN+ V+ A G+ L+NKY EG+PG RYYGG I Sbjct: 9 DQQISELINLESKRQNSQIELIASENYASEDVILANGTSLSNKYGEGYPGKRYYGGCTFI 68 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D IE++ +R F ++ A NVQPYS +SAN AV+ LL P D+I+GL+ +GGH+ Sbjct: 69 DQIEKIAIERVKKLFKIEYA----NVQPYSGSSANAAVFAALLKPGDKILGLDLNAGGHL 124 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 SHGY K++ + +F+ +SY ++ + +DYD +E A+ P ++ICG S+Y R+ Sbjct: 125 SHGY------KINFSGMFYSGISYFLD-ENELLDYDAIEKIALKTKPNLIICGYSAYSRK 177 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFAR R IADK A L+ D+AHI+GL+AA + SP Y ++TSTT K LRGPRGG+I Sbjct: 178 IDFARFRQIADKVNAFLLADIAHIAGLIAAGQHPSPVGYAHIITSTTQKTLRGPRGGLIL 237 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 N + KI+ VFP +QGGP + IAA A+ K+ P + Sbjct: 238 ------------------TNSKEIAAKIDKVVFPGIQGGPFFHTIAAKAVAFKEALEPWF 279 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWD-LRTFGLTGKNFEKVCELCHIS 1719 K Y Q++KNA AS +++ R+V+ GT+NHL D L ++ L GK + + E +I Sbjct: 280 KEYCAQIVKNASHFASEFIKKGIRIVSQGTENHLFTIDVLSSYNLNGKQAQILLESVNII 339 Query: 1720 INKTPIYGDNGSISP---GGVRIGTPAMTTRGCLEDDFEVIA---DFLIRATQIAGSVLK 1881 NK I N ++SP G+R+GTPAMT+RG E +F +A DF++R ++ +K Sbjct: 340 TNKNTI--PNDTLSPFVTSGLRLGTPAMTSRGFKEQEFSQMAEIIDFVLRKKELNALEIK 397 Query: 1882 QHGKVQK 1902 + K K Sbjct: 398 EIKKKVK 404
>Q3SGX5:GLYA_THIDA Serine hydroxymethyltransferase - Thiobacillus denitrificans (strain| ATCC 25259) Length = 414 Score = 297 bits (760), Expect = 1e-79 Identities = 174/407 (42%), Positives = 235/407 (57%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DPD+ A +++E RQ IELIASEN+ AV+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 LAKTDPDLWAAIQQEDRRQQDHIELIASENYTSPAVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG + A NVQP S + AN AV+ L P D IMG+ Sbjct: 68 CEYVDIVEQLAIDRVKALFGAEAA----NVQPNSGSQANQAVFMAFLKPGDTIMGMSLAE 123 Query: 991 GGHVSHGY-YTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 GGH++HG SGK +F ++Y +N + IDY+ +E A + PK++I G S Sbjct: 124 GGHLTHGMALNMSGK-------WFNVVAYGLNEKEE-IDYEAMERLAREHKPKLIIAGAS 175 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 +Y DF R IA + GA+ M DMAH +GL+AA +P + DVVTSTTHK LRGPR Sbjct: 176 AYALRIDFERFAKIAKEIGAIFMVDMAHYAGLIAAGLYPNPVPHADVVTSTTHKTLRGPR 235 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 GGII + + E IN A+FP LQGGP + IA A K+ Sbjct: 236 GGIILMKA-------------------EHEKAINSAIFPGLQGGPLMHVIAGKATAFKEA 276 Query: 1528 ATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCEL 1707 AT ++K Y +QV+ NA + L+ R R+++G T++H+ L DLR LTGK E + Sbjct: 277 ATKDFKRYQEQVIDNALVMCKVLVERGLRIISGRTESHVFLVDLRAKNLTGKEAEALLGR 336 Query: 1708 CHISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D G+RIGTPAMTTRG E + E +A + Sbjct: 337 AHITVNKNAIPNDPQKPFVTSGIRIGTPAMTTRGFTELEAEQLAHLI 383
>Q92XS8:GLYA2_RHIME Serine hydroxymethyltransferase 2 - Rhizobium meliloti (Sinorhizobium| meliloti) Length = 422 Score = 296 bits (759), Expect = 2e-79 Identities = 180/422 (42%), Positives = 243/422 (57%), Gaps = 2/422 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + + RE RQ IELIASEN V AVL A GS +TNKY+EG+PG RYYGG Q++ Sbjct: 12 DSVIAGAIAREMGRQRSEIELIASENIVSPAVLAAQGSVMTNKYAEGYPGHRYYGGCQYV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E +RA F VNVQP+S AN AV LL P D MGL +GGH+ Sbjct: 72 DLVEAAAIERAGMLFDAS----FVNVQPHSGAQANGAVMLALLKPGDTFMGLSLAAGGHL 127 Query: 1003 SHGYY-TPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPR 1179 +HG T SGK +F ++ Y V IDYD+LE +A+ PK++I GGS+YPR Sbjct: 128 THGARPTMSGK-------WFNAVQYGVRESDCLIDYDELEVKAIATRPKLIITGGSAYPR 180 Query: 1180 EWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGII 1359 DF R+R IAD GA +M DMAH +GLVA +P + D+VT+TTHK LRGPRGG+I Sbjct: 181 LIDFKRIRAIADSVGAAMMVDMAHFAGLVAGGVHPNPVEIADIVTTTTHKTLRGPRGGMI 240 Query: 1360 FFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPE 1539 N+ D K+N AVFP LQGGP + IAA A+ L + Sbjct: 241 L------------------TNNQDVAKKVNSAVFPGLQGGPLMHVIAAKAVALGEALEDN 282 Query: 1540 YKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHIS 1719 ++ Y +Q++ NA+ALASAL R +V+GGTD HL+L DLR+ G++GK+ E+ ++ Sbjct: 283 FRQYARQMVANARALASALTERGYDIVSGGTDTHLILVDLRSKGVSGKDAEEALGRAGLT 342 Query: 1720 INKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQHGKV 1896 NK I D + G+R+GTPA T+RG E +F + + G+ +Q G+ Sbjct: 343 CNKNGIPFDPAPPAVTSGIRLGTPAATSRGFREAEFNEVGALIANVLDALGT--EQSGEQ 400 Query: 1897 QK 1902 ++ Sbjct: 401 ER 402
>Q481S6:GLYA2_COLP3 Serine hydroxymethyltransferase 2 - Colwellia psychrerythraea (strain| 34H / ATCC BAA-681) (Vibrio psychroerythus) Length = 417 Score = 296 bits (759), Expect = 2e-79 Identities = 172/396 (43%), Positives = 232/396 (58%), Gaps = 1/396 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N +A D + ME+E RQ +ELIASEN+ V+ A GS LTNKY+EG+PG RY Sbjct: 5 NDQIAGFDDSIWQAMEQEDKRQQDHVELIASENYTSARVMQAQGSQLTNKYAEGYPGKRY 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +H+D IE+L RA FG D A NVQP+S + AN AV+ LL P + ++G+ Sbjct: 65 YGGCEHVDVIEQLAIDRAKELFGADYA----NVQPHSGSQANAAVFMALLKPGETVLGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG KVS + + ++ Y +N TG IDY+++E A + PK++I G Sbjct: 121 LAHGGHLTHG------SKVSFSGKIYNAVQYGLNEATGEIDYEEVERLAKEHQPKMIIAG 174 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y R D+ R R IAD GA L DMAH++GLVAA +P DVVT+TTHK LRG Sbjct: 175 FSAYSRVVDWQRFRDIADSIGAWLFVDMAHVAGLVAAGLYPNPVPIADVVTTTTHKTLRG 234 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I ++ + K K+N AVFP+ QGGP + IAA AI K Sbjct: 235 PRGGLILAKQNDELAK-----------------KLNSAVFPAGQGGPLMHVIAAKAICFK 277 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + Y Y QQV+ NA+ +A R +V+GGTDNHL L DL G+TGK+ + Sbjct: 278 EALGEGYVEYQQQVIDNAREMAKTFQTRGYNVVSGGTDNHLFLLDLIDKGITGKDADAAL 337 Query: 1702 ELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRG 1806 +I++NK + D S G+RIGTPA+T+RG Sbjct: 338 GRANITVNKNSVPNDPQSPFVTSGLRIGTPAITSRG 373
>Q8F6A0:GLYA_LEPIN Serine hydroxymethyltransferase - Leptospira interrogans| Length = 415 Score = 296 bits (758), Expect = 2e-79 Identities = 169/408 (41%), Positives = 238/408 (58%), Gaps = 1/408 (0%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 Q L +ADP++ A +++E +RQ +E+IASENFV RAVL+A S LTNKY+EG+PG RYY Sbjct: 2 QFLPKADPEIFAALKKEDERQENNLEMIASENFVSRAVLEAYTSTLTNKYAEGYPGKRYY 61 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 G + D +E L +RA FG A NVQP+S AN+AV+ L P D +G+ Sbjct: 62 NGCHNADVVETLAIERAKKLFGSQYA----NVQPHSGAQANMAVFLACLEPGDSFLGMNL 117 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 GGH++HG S VSG ++ + Y V+ +T I+YD++ A + PK+++ G Sbjct: 118 AHGGHLTHG----SPVNVSGK--IYKPIPYGVDSKTETINYDEVAKLAREHKPKLIVAGA 171 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S+Y R DF++ IA + GA LM D+AHISGLVA SP D VT+TTHK LRGP Sbjct: 172 SAYARTIDFSKFAEIAKEVGAKLMADIAHISGLVATGYHPSPIGMFDFVTTTTHKTLRGP 231 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 RGG+I + + E +N VFP +QGGP + IAA A+ ++ Sbjct: 232 RGGLIL-------------------STLENEKVLNSRVFPGIQGGPLMHVIAAKAVAFQE 272 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 P+YK YI+ V+ NA+ LA ++R R+V+GGTDNHLVL D+ GLTG + Sbjct: 273 ALQPDYKKYIETVLANAKTLAEVFVKRGYRVVSGGTDNHLVLLDVSVKGLTGAQAADGLD 332 Query: 1705 LCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +++NK I + N G+R+GTPA+TTRG D E + + + Sbjct: 333 EVGVTVNKNAIPFDKNPPAVASGIRLGTPALTTRGLKPADMETVGNLI 380
>Q72PY2:GLYA_LEPIC Serine hydroxymethyltransferase - Leptospira interrogans serogroup| Icterohaemorrhagiae serovar copenhageni Length = 415 Score = 296 bits (758), Expect = 2e-79 Identities = 169/408 (41%), Positives = 238/408 (58%), Gaps = 1/408 (0%) Frame = +1 Query: 625 QPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYY 804 Q L +ADP++ A +++E +RQ +E+IASENFV RAVL+A S LTNKY+EG+PG RYY Sbjct: 2 QFLPKADPEIFAALKKEDERQENNLEMIASENFVSRAVLEAYTSTLTNKYAEGYPGKRYY 61 Query: 805 GGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEP 984 G + D +E L +RA FG A NVQP+S AN+AV+ L P D +G+ Sbjct: 62 NGCHNADVVETLAIERAKKLFGSQYA----NVQPHSGAQANMAVFLACLEPGDSFLGMNL 117 Query: 985 PSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGG 1164 GGH++HG S VSG ++ + Y V+ +T I+YD++ A + PK+++ G Sbjct: 118 AHGGHLTHG----SPVNVSGK--IYKPIPYGVDSKTETINYDEVAKLAREHKPKLIVAGA 171 Query: 1165 SSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGP 1344 S+Y R DF++ IA + GA LM D+AHISGLVA SP D VT+TTHK LRGP Sbjct: 172 SAYARTIDFSKFAEIAKEVGAKLMADIAHISGLVATGYHPSPIGMFDFVTTTTHKTLRGP 231 Query: 1345 RGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQ 1524 RGG+I + + E +N VFP +QGGP + IAA A+ ++ Sbjct: 232 RGGLIL-------------------STLENEKVLNSRVFPGIQGGPLMHVIAAKAVAFQE 272 Query: 1525 VATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 P+YK YI+ V+ NA+ LA ++R R+V+GGTDNHLVL D+ GLTG + Sbjct: 273 ALQPDYKKYIETVLANAKTLAEVFVKRGYRVVSGGTDNHLVLLDVSVKGLTGAQAADGLD 332 Query: 1705 LCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +++NK I + N G+R+GTPA+TTRG D E + + + Sbjct: 333 EVGVTVNKNAIPFDKNPPAVASGIRLGTPALTTRGLKPADMETVGNLI 380
>Q5FMC0:GLYA_LACAC Serine hydroxymethyltransferase - Lactobacillus acidophilus| Length = 411 Score = 296 bits (758), Expect = 2e-79 Identities = 173/407 (42%), Positives = 242/407 (59%), Gaps = 2/407 (0%) Frame = +1 Query: 634 AEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGN 813 AE P + + +E RQ IELIASEN V AV +A GS LTNKY+EG+PG RYYGG Sbjct: 4 AEKSPALWDAIRQEEKRQQNTIELIASENIVSDAVREAQGSVLTNKYAEGYPGRRYYGGC 63 Query: 814 QHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSG 993 Q+ID +E+L A F A NVQP+S + AN+AVY LL P D I+G+ +G Sbjct: 64 QYIDQVEQLAIDYAKKLFNAKFA----NVQPHSGSQANMAVYQALLKPGDVILGMGMDAG 119 Query: 994 GHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSY 1173 GH++HG KV+ + ++S Y +N +T +D+D++ A++ PK+++ G S+Y Sbjct: 120 GHLTHG------AKVNFSGKEYKSYEYGLNVETEELDFDQIRKVALEVKPKLIVAGASAY 173 Query: 1174 PREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGG 1353 R D+ + R IAD+ GA LM DMAHI+GLVA + SP D+VT+TTHK LRGPRGG Sbjct: 174 SRIIDWQKFRDIADEVGAYLMVDMAHIAGLVATDQHPSPIPVADIVTTTTHKTLRGPRGG 233 Query: 1354 IIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVAT 1533 +I N+ + KIN A+FP +QGGP + IA A + Sbjct: 234 MIL------------------SNNLEIGKKINSALFPGIQGGPLEHVIAGKAQAFYEDLQ 275 Query: 1534 PEYKAYIQQVMKNAQALASAL-LRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 P++ YI+QV+KNA+A+A R+V+GGTDNHL++ D+ GLTGK+ + + + Sbjct: 276 PQFTDYIKQVVKNAKAMAEVFDESENIRVVSGGTDNHLMIIDITDTGLTGKDAQNLLDFV 335 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLI 1848 +I+ NK I GD S G+RIGTPA+T+RG E+D A +I Sbjct: 336 NITTNKESIPGDKRSPFITSGLRIGTPAITSRGFNEEDARKTASLII 382
>Q6D246:GLYA1_ERWCT Serine hydroxymethyltransferase 1 - Erwinia carotovora subsp.| atroseptica (Pectobacterium atrosepticum) Length = 417 Score = 296 bits (758), Expect = 2e-79 Identities = 173/406 (42%), Positives = 238/406 (58%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ D D+ ME+E RQ IELIASEN+ V+ A GS LTNKY+EG+PG RYYGG Sbjct: 8 IADYDADLWQAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L RA FG D A NVQP+S + AN AVYT LL P D I+G+ Sbjct: 68 CEYVDIVEQLAIDRAKALFGADYA----NVQPHSGSQANFAVYTALLQPGDTILGMNLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG S +SG ++ + Y ++ ++G IDYD++ + A PK+++ G S+ Sbjct: 124 GGHLTHG----SPVNLSGK--LYKVIPYGID-ESGKIDYDEMAELARTHQPKMIVGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y D+A+MR IAD GA L DMAH++GL+AA +P + +VT+TTHK L GPRG Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAADVYPNPVPHAHIVTTTTHKTLAGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + G D D K+N AVFP QGGP + IA A+ LK+ Sbjct: 237 GLILAKGG----------------DEDLYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAM 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K Y QQV KNA+A+ L R +V+G T NHL L DL + LTGK + Sbjct: 281 EPEFKVYQQQVAKNAKAMVEVFLSRGFNVVSGATSNHLFLLDLVSKNLTGKEADAALGRA 340 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D S G+RIGTPA T RG E + +A ++ Sbjct: 341 NITVNKNSVPNDPKSPFVTSGIRIGTPAATRRGFKEAEVRELAGWI 386
>Q6MS85:GLYA_MYCMS Serine hydroxymethyltransferase - Mycoplasma mycoides subsp. mycoides| SC Length = 413 Score = 296 bits (757), Expect = 3e-79 Identities = 169/405 (41%), Positives = 238/405 (58%), Gaps = 2/405 (0%) Frame = +1 Query: 646 PDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHID 825 P + + +E RQ IELIASEN+V +AVL+ GS LTNKY+EG+PG RYYGG + ID Sbjct: 7 PLIKESLNKELKRQQSHIELIASENYVSKAVLELNGSVLTNKYAEGYPGKRYYGGCEFID 66 Query: 826 AIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHVS 1005 IE L Q A F + A N+QP+S + AN A Y LL P DR++ + +GGH++ Sbjct: 67 EIESLGIQTAKELFHAEHA----NIQPHSGSQANDAAYKALLEPKDRVVAMSLDAGGHLT 122 Query: 1006 HGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPREW 1185 HGY ++ + ++ Y VN T +DY ++E ++ PK+++ G S+Y R Sbjct: 123 HGY------PINFSGYTYDFRFYGVNKDTEQLDYQEIEKIVLEHKPKLIVAGASAYSRII 176 Query: 1186 DFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIFF 1365 DF + + IADK GA LM DMAHI+GLVAA +P +Y D+VT+TTHK LRG RGG+I Sbjct: 177 DFKKFKEIADKVGAYLMVDMAHIAGLVAAGVHPNPLEYADIVTTTTHKTLRGARGGLILC 236 Query: 1366 RKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEYK 1545 ++ +F K++ AVFP QGGP N IA L + +T E+K Sbjct: 237 KQ-------------------EFAKKVDLAVFPGSQGGPLENLIAGKTQALLEASTDEFK 277 Query: 1546 AYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLR-TFGLTGKNFEKVCELCHISI 1722 Y +Q++KN +ALA+ L RLV GG+DNHL+ D++ T +TGK EK+ E I Sbjct: 278 EYGKQIVKNTKALANVLQENGLRLVAGGSDNHLINVDVKSTLRITGKKAEKILESIGIIC 337 Query: 1723 NKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 NK I + G+R+GTPAMTTRG E++F+ + ++ A Sbjct: 338 NKNMIPFDTEKPFYTSGIRLGTPAMTTRGFKEEEFKQVGLIIVNA 382
>Q8TK94:GLYA_METAC Serine hydroxymethyltransferase - Methanosarcina acetivorans| Length = 412 Score = 296 bits (757), Expect = 3e-79 Identities = 169/415 (40%), Positives = 239/415 (57%), Gaps = 1/415 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + DPD+ +++E DRQ + LIASEN+ RAV++A GS +TNKY+EG+ G RYYGG Sbjct: 4 IEKIDPDMFEAIQKEADRQEHKLNLIASENYASRAVMEAQGSIMTNKYAEGYSGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +D E L RA FG VNVQP+S + AN+AVY +L P D IM ++ Sbjct: 64 CDFVDIAENLAIARAKEIFGAKY----VNVQPHSGSGANMAVYFSVLQPGDTIMSMDLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH+SHG VS + + + Y V+ +T +DYD+L A + PK+++CG S+ Sbjct: 120 GGHLSHG------SPVSFSGKLYNIVPYGVSKETEALDYDELMKMAKECKPKMIVCGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF + R IAD+ GA L+ D+AHI+GLV + SP Y D VT+TTHK LRGPRG Sbjct: 174 YPRVIDFKKFREIADEVGAYLLADIAHIAGLVVSGVHPSPVPYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + + G +N AVFP +QGGP + IAA A+ K+ Sbjct: 234 GMII--------SKTEELAMG----------VNKAVFPGIQGGPLMHVIAAKAVAFKEAM 275 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 +++ Q +KNA+ L + L + +V+GGTDNHL+L +L +TGK+ E Sbjct: 276 DEKFRQDQAQTVKNAKVLCACLKEKGFDIVSGGTDNHLMLVNLNNMNITGKDAEAAMSKA 335 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGS 1872 I NK + + GVR+GTPA TTRG E + E+IAD++ A + AG+ Sbjct: 336 GIIANKNTVPFETRSPFITSGVRLGTPACTTRGMKEKEMELIADYIETAIKNAGN 390
>Q6ADF0:GLYA_LEIXX Serine hydroxymethyltransferase - Leifsonia xyli subsp. xyli| Length = 430 Score = 296 bits (757), Expect = 3e-79 Identities = 174/414 (42%), Positives = 243/414 (58%), Gaps = 6/414 (1%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LAE DP++ +++ E RQ +E+IASENFV RAVL+++GS LTNKY+EG+PG RYYGG Sbjct: 13 LAEVDPEIAEVLQLELGRQRDYLEMIASENFVPRAVLESVGSVLTNKYAEGYPGRRYYGG 72 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D E+L RA + FG + A NVQP+S SAN AV + + P + I+GLE Sbjct: 73 CEYVDIAEQLAIDRAKSLFGAEYA----NVQPHSGASANAAVLSAIATPGETILGLELAH 128 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG K++ + + +++Y V+P+T +D D + DRA++ P+++I G S+ Sbjct: 129 GGHLTHGM------KLNFSGKLYNAVAYGVDPETFLVDMDAVRDRALEHKPQVIIAGWSA 182 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR+ DFA R IAD+ GA L DMAH +GLVAA SP Y DVV+ST HK L GPR Sbjct: 183 YPRQLDFAAFRAIADEVGAKLWVDMAHFAGLVAAGLHPSPVPYADVVSSTVHKTLGGPRS 242 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G I R D + K+N VFP QGGP + IAA A K A Sbjct: 243 GFIVSR------------------DTELAKKLNSNVFPGQQGGPLMHVIAAKATAFKLAA 284 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCR-----LVTGGTDNHLVLWDLRTFGLTGKNFEK 1695 T E+K + ++ AQ LA L R ++TGGTD HLVL DLRT L G+ E Sbjct: 285 TDEFKDRQARTIRGAQLLAERLTAADSRASGVDVLTGGTDVHLVLADLRTSELDGQQAED 344 Query: 1696 VCELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 + I++N+ + + + G+RIGTPA+ TRG + +F +AD + A Sbjct: 345 ILHEVGITVNRNAVPFDPRPPMVTSGLRIGTPALATRGFGDTEFTEVADIIALA 398
>Q30YL7:GLYA_DESDG Serine hydroxymethyltransferase - Desulfovibrio desulfuricans (strain| G20) Length = 412 Score = 296 bits (757), Expect = 3e-79 Identities = 178/449 (39%), Positives = 247/449 (55%), Gaps = 1/449 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP+V + +E +RQ +ELIASENFV AV A GS LT+KY+EG+PG RYYGG + + Sbjct: 8 DPEVGRAIVQEVERQTGKLELIASENFVSPAVRAAQGSVLTHKYAEGYPGKRYYGGCEFV 67 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E L RA FG A NVQP+S + AN+AVY L P D I+ ++ GGH+ Sbjct: 68 DVAENLAIDRACEIFGAQYA----NVQPHSGSQANMAVYFSALTPGDTILAMDLSHGGHL 123 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG V+ + F+ + Y V+ +TG IDYD + + A + P +++ G S+Y R Sbjct: 124 THG------SPVNFSGRFYNVVFYGVSRETGCIDYDSVAELAREHRPAMIVAGASAYSRI 177 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFAR R IAD+ G++LM DMAHI+GLVAA SP T+TTHK LRGPRGG+I Sbjct: 178 IDFARFRAIADEVGSLLMVDMAHIAGLVAAGLHPSPVGTAHFTTTTTHKTLRGPRGGMIL 237 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 +D + K+N +FP +QGGP + IAA A+ + PE+ Sbjct: 238 -------------------SDEEAAKKLNSQIFPGIQGGPLMHVIAAKAVAFGEALRPEF 278 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 AY +QV+ NA LA+ L LV+GGTDNHL+L DL +TGK+ + +L I+ Sbjct: 279 GAYQKQVVANAAKLAATLTDAGFELVSGGTDNHLMLVDLTNKDITGKDAQHALDLAGITA 338 Query: 1723 NKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQHGKVQ 1899 NK + + G+R+GTPA+TTRG E + +A ++I A Sbjct: 339 NKNTVPFETRSPFVTSGIRLGTPALTTRGMKEAEMVKVAGWIIDA--------------- 383 Query: 1900 KEFLRGLENNKDIIELGNQVEAFASQFAM 1986 L + N + E+ VE FA QF + Sbjct: 384 ---LGNIGNETRLAEISRDVEKFARQFPL 409
>P34894:GLYA_ACTAC Serine hydroxymethyltransferase - Actinobacillus| actinomycetemcomitans (Haemophilus actinomycetemcomitans) Length = 420 Score = 296 bits (757), Expect = 3e-79 Identities = 174/406 (42%), Positives = 239/406 (58%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A+ DP + +E E RQ IELIASEN+ V+ A GS TNKY+EG+PG RYYGG Sbjct: 8 IADYDPVLWQAIENENRRQEEHIELIASENYASPRVMQAQGSQFTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 ++ D +E+L +RA FG D VNVQP+S + AN AVY GLL P D I+G+ Sbjct: 68 CEYADIVEQLAIERAKELFGADY----VNVQPHSGSQANAAVYMGLLNPGDTILGMSLAH 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG VS + + + Y + + G IDYD L +A D PK+++ G S+ Sbjct: 124 GGHLTHG------ASVSFSGKIYHAEQYGITDE-GLIDYDALRKQAHDVKPKMIVGGFSA 176 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y + D+ +MR IAD+ GA L DMAH++GLVAA +P Y VVT+TTHK L GPRG Sbjct: 177 YSQVVDWKKMREIADEVGAYLFVDMAHVAGLVAAGIYPNPLPYAHVVTTTTHKTLGGPRG 236 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I S GDE Y K+N AVFP+ QGGP + IAA A+ K+ Sbjct: 237 GLIL-------------SSCGDEEIY---KKLNSAVFPAGQGGPLVHIIAAKAVCFKEAL 280 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PEYK Y Q V+KNA+A+ +R ++V+ GT+NHL L DL + GLTGK + Sbjct: 281 EPEYKVYQQNVLKNAKAMVEVFKQRCYKVVSNGTENHLFLVDLVSHGLTGKAADAALGKA 340 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I++NK + D G+R+GTP++T RG E D + +A ++ Sbjct: 341 NITVNKNSVPNDPQKPFITSGIRVGTPSVTRRGFNEADVKELAGWM 386
>Q9K6G4:GLYA_BACHD Serine hydroxymethyltransferase - Bacillus halodurans| Length = 413 Score = 295 bits (756), Expect = 4e-79 Identities = 176/453 (38%), Positives = 256/453 (56%), Gaps = 1/453 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L DP V +++E RQ IELIASENFV AV++A S LTNKY+EG+PG RYYGG Sbjct: 4 LQSKDPKVFEAVQQELGRQRDKIELIASENFVSEAVMEAQSSVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E L RA FG + VNVQP+S AN+AVY +L D ++G+ Sbjct: 64 CEYVDIVEDLARDRAKEIFGGEH----VNVQPHSGAQANMAVYFTILEHGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + I + + Y V+ ++ IDY+++ A + PK+++ G S+ Sbjct: 120 GGHLTHG------SPVNFSGIQYNFVEYGVDKESQRIDYEEVRRLAKEHQPKMIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPRE DFA+ R IAD+ GA LM DMAHI+GLVAA ++P + VT+TTHK LRGPRG Sbjct: 174 YPREIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPHSHFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + +F +I+ ++FP +QGGP + IAA A+ + Sbjct: 234 GMIICNE-------------------EFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+K+Y + +++NA+ L L LV+GGTDNHL+L DLR+ GLTGK EK + Sbjct: 275 QPEFKSYGEAIIRNAKRLGEKLTSEGIDLVSGGTDNHLLLLDLRSLGLTGKVAEKALDDV 334 Query: 1711 HISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I+ NK I + G+RIGT A+T+RG E+ + I Sbjct: 335 GITTNKNTIPFDPESPFVTSGIRIGTAAVTSRGLDEEAMDEI------------------ 376 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 G L+ ++N + + E +V+A ++F M Sbjct: 377 GATIALTLKNVDNEEKMNEARERVDALTAKFPM 409
>Q47WY2:GLYA4_COLP3 Serine hydroxymethyltransferase 4 - Colwellia psychrerythraea (strain| 34H / ATCC BAA-681) (Vibrio psychroerythus) Length = 417 Score = 295 bits (756), Expect = 4e-79 Identities = 172/396 (43%), Positives = 231/396 (58%), Gaps = 1/396 (0%) Frame = +1 Query: 622 NQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARY 801 N +A D + ME+E RQ +ELIASEN+ V+ A GS LTNKY+EG+PG RY Sbjct: 5 NDQIAGFDDSIWQAMEQEDKRQQDHVELIASENYTSARVMQAQGSQLTNKYAEGYPGKRY 64 Query: 802 YGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLE 981 YGG +H+D IE+L RA FG D A NVQP+S + AN AV+ LL P + ++G+ Sbjct: 65 YGGCEHVDVIEQLAIDRAKELFGADYA----NVQPHSGSQANAAVFMALLKPGETVLGMS 120 Query: 982 PPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICG 1161 GGH++HG KVS + + ++ Y +N TG IDYD++ A + PK++I G Sbjct: 121 LAHGGHLTHG------SKVSFSGKIYNAVQYGLNEVTGEIDYDEVARLAKEHQPKMIIAG 174 Query: 1162 GSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRG 1341 S+Y R D+ R R IAD GA L DMAH++GLVAA +P DVVT+TTHK LRG Sbjct: 175 FSAYSRVVDWQRFRDIADSIGAWLFVDMAHVAGLVAAGLYPNPVPIADVVTTTTHKTLRG 234 Query: 1342 PRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLK 1521 PRGG+I ++ + K K+N AVFP+ QGGP + IAA AI K Sbjct: 235 PRGGLILAKQNDELAK-----------------KLNSAVFPAGQGGPLMHVIAAKAICFK 277 Query: 1522 QVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVC 1701 + Y Y QQV+ NA+ +A R +V+GGTDNHL L DL G+TGK+ + Sbjct: 278 EALGEGYVEYQQQVIDNAREMAKTFQTRGYNVVSGGTDNHLFLLDLIDKGITGKDADAAL 337 Query: 1702 ELCHISINKTPIYGDNGS-ISPGGVRIGTPAMTTRG 1806 +I++NK + D S G+RIGTPA+T+RG Sbjct: 338 GRANITVNKNSVPNDPQSPFVTSGLRIGTPAITSRG 373
>P56089:GLYA_HELPY Serine hydroxymethyltransferase - Helicobacter pylori (Campylobacter| pylori) Length = 416 Score = 295 bits (755), Expect = 6e-79 Identities = 172/404 (42%), Positives = 237/404 (58%), Gaps = 1/404 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L + D ++ L+ E RQ +E+IASEN+ +V++A+GS LTNKY+EG+P RYYGG Sbjct: 5 LEQTDSEIFELIFEEYKRQNEHLEMIASENYTFASVMEAMGSVLTNKYAEGYPNKRYYGG 64 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D IE L +RA F C NVQ +S + AN AVY LL P D+I+G++ Sbjct: 65 CEVVDKIESLAIERAKKLFN----CQFANVQAHSGSQANNAVYHALLKPYDKILGMDLSC 120 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG KVS ++S SY VN GYIDY++ A P+I++CG S+ Sbjct: 121 GGHLTHG------AKVSLTGKHYQSFSYGVNLD-GYIDYEEALKIAQSVKPEIIVCGFSA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPRE DF + R IAD+ GA+L+ D+AH++GLV E PF +C VV+STTHK LRGPRG Sbjct: 174 YPREIDFKKFREIADEVGALLLGDIAHVAGLVVTGEHAHPFPHCHVVSSTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 GII ND + KI+ A+FP QGGP + IAA A+ K+ Sbjct: 234 GIIL------------------TNDEEIAAKIDKAIFPGTQGGPLMHVIAAKAVGFKENL 275 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+KAY Q V N Q LA AL + +LV+GGT NHL+L D +GK+ + Sbjct: 276 KPEFKAYAQLVKSNMQVLAKALKEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNA 335 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIAD 1839 I++NK I G+ S G+RIG+ A++ RG +FE+I + Sbjct: 336 GITVNKNTIPGETRSPFVTSGIRIGSAALSARGMGAKEFEIIGN 379
>Q39J72:GLYA3_BURS3 Serine hydroxymethyltransferase 3 - Burkholderia sp. (strain 383)| (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) Length = 415 Score = 295 bits (755), Expect = 6e-79 Identities = 164/393 (41%), Positives = 234/393 (59%), Gaps = 1/393 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A DP++ A +E+E RQ IELIASEN+ AV+ A GS LTNKY+EG+PG RYYGG Sbjct: 9 IANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG + A NVQP S + AN V+ +L P D IMG+ Sbjct: 69 CEYVDVVEQLAIDRVKQLFGAEAA----NVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 124 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F +SY +N IDY+ E A + PK+++ G S+ Sbjct: 125 GGHLTHG------SPVNMSGKWFNVVSYGLNENED-IDYEAAEQLAQEHKPKLIVAGASA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 + + DF R+ IA GA LM DMAH +GL+AA +P + D VT+TTHK+LRGPRG Sbjct: 178 FSLKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++E IN A+FP +QGGP + IA A+ K+ Sbjct: 238 GVILMKA-------------------EYEKPINSAIFPGIQGGPLMHVIAGKAVAFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 +PE+KAY ++V++NA+ LA L++R R+V+G T++H++L DLR +TGK E Sbjct: 279 SPEFKAYQEKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRG 1806 HI++NK I D GVR+G+PAMTTRG Sbjct: 339 HITVNKNAIPNDPEKPFVTSGVRLGSPAMTTRG 371
>Q87AS2:GLYA_XYLFT Serine hydroxymethyltransferase - Xylella fastidiosa (strain| Temecula1 / ATCC 700964) Length = 417 Score = 295 bits (754), Expect = 7e-79 Identities = 172/402 (42%), Positives = 241/402 (59%), Gaps = 1/402 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP++ + E RQ +ELIASEN+ V+ GS LTNKY+EG+ G RYYGG +++ Sbjct: 12 DPELAKAIAAEVRRQEDHVELIASENYCSTLVMQVQGSQLTNKYAEGYSGKRYYGGCEYV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E+L +RA FG D A NVQP+S + AN AVY LL P D I+G+ GGH+ Sbjct: 72 DIAEQLAIERAKKLFGADYA----NVQPHSGSQANQAVYFALLQPGDTILGMSLAHGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG + VSG F ++ Y VN Q G IDY+ +E A++ PK+++ G S+Y ++ Sbjct: 128 THG----ANVNVSGK--LFNAVQYGVNAQ-GLIDYEAVESLALEHRPKMVVAGFSAYSQK 180 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 D+AR R IAD+ GA L+ DMAH++GLVAA SP + VVTSTTHK LRGPRGGII Sbjct: 181 IDWARFRAIADQVGAYLLVDMAHVAGLVAAGVYPSPLPHAHVVTSTTHKTLRGPRGGIIV 240 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 + + + K+ VFP +QGGP + IAA A+ K+ P + Sbjct: 241 AQAPQEALVK----------------KLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAF 284 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y QQV+KNA+A+A L+ R ++V+GGT+NHL+L D+ ++GK+ E HI++ Sbjct: 285 KVYQQQVVKNAKAMAGTLMLRGYKIVSGGTENHLMLVDMIGRDVSGKDAEGALGQVHITV 344 Query: 1723 NKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 NK + D S G+R+GTPA+TTRG E D +A ++ Sbjct: 345 NKNAVPDDPRSPFVTSGLRLGTPAVTTRGYQEQDCVDLAHWI 386
>Q4AAB2:GLYA_MYCHJ Serine hydroxymethyltransferase - Mycoplasma hyopneumoniae (strain J| / ATCC 25934 / NCTC 10110) Length = 418 Score = 295 bits (754), Expect = 7e-79 Identities = 174/427 (40%), Positives = 250/427 (58%), Gaps = 7/427 (1%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + L+ E RQ IELIASEN+ V+ A G+ +NKY EG+PG RYYGG I Sbjct: 9 DQQISELINLESKRQNSQIELIASENYASEDVILANGTSPSNKYGEGYPGKRYYGGCTFI 68 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D IE++ +R F ++ A NVQPYS +SAN AV+ LL P D+I+GL+ +GGH+ Sbjct: 69 DQIEKIAIERVKKLFKIEYA----NVQPYSGSSANAAVFAALLKPGDKILGLDLNAGGHL 124 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 SHGY K++ + +F+ +SY ++ + +DYD +E A+ P ++ICG S+Y R+ Sbjct: 125 SHGY------KINFSGMFYSGISYFLD-ENELLDYDAIEKIALKTKPNLIICGYSAYSRK 177 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFAR R IADK A L+ D+AHI+GL+AA + SP Y ++TSTT K LRGPRGG+I Sbjct: 178 IDFARFRQIADKVNAFLLADIAHIAGLIAAGQHPSPVGYAHIITSTTQKTLRGPRGGLIL 237 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 N + KI+ VFP +QGGP + IAA A+ K+ P + Sbjct: 238 ------------------TNSKEIAAKIDKVVFPGIQGGPFFHTIAAKAVAFKEALEPWF 279 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWD-LRTFGLTGKNFEKVCELCHIS 1719 K Y Q++KNA AS +++ R+V+ GT+NHL D L ++ L GK + + E +I Sbjct: 280 KEYCAQIVKNASHFASEFIKKGIRIVSQGTENHLFTIDVLSSYNLNGKQAQILLESVNII 339 Query: 1720 INKTPIYGDNGSISP---GGVRIGTPAMTTRGCLEDDFEVIA---DFLIRATQIAGSVLK 1881 NK I N ++SP G+R+GTPAMT+RG E +F +A DF++R ++ +K Sbjct: 340 TNKNTI--PNDTLSPFVTSGLRLGTPAMTSRGFKEQEFSQMAEIIDFVLRKKELNALEIK 397 Query: 1882 QHGKVQK 1902 + K K Sbjct: 398 EIKKKVK 404
>Q6HAW9:GLYA_BACHK Serine hydroxymethyltransferase - Bacillus thuringiensis subsp.| konkukian Length = 414 Score = 295 bits (754), Expect = 7e-79 Identities = 179/453 (39%), Positives = 249/453 (54%), Gaps = 1/453 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L D V A +E E RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 5 LKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 64 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E + R FG + VNVQP+S AN+AVY +L D ++G+ Sbjct: 65 CEHVDVVEDIARDRVKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSH 120 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + + Y V+ ++ I+YD + +A + PK+++ G S+ Sbjct: 121 GGHLTHG------SPVNFSGVQYNFVEYGVDAESHRINYDDVLAKAKEHKPKLIVAGASA 174 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF R R IAD+ GA LM DMAHI+GLVAA +P + VT+TTHK LRGPRG Sbjct: 175 YPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRG 234 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + F +I+ ++FP +QGGP + IAA A+ + Sbjct: 235 GMILCEE-------------------QFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEAL 275 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 ++K Y Q ++ NA LA L + LV+GGTDNHL+L D+R +TGK E V + Sbjct: 276 QDDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEV 335 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I++NK I + S GVRIGT A+T+RG +D + IA + LK H Sbjct: 336 GITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEDMDEIASLI-------AYTLKNH 388 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 EN + E +VEA S+F M Sbjct: 389 -----------ENEAALEEARKRVEALTSKFPM 410
>Q81JY4:GLYA_BACAN Serine hydroxymethyltransferase - Bacillus anthracis| Length = 413 Score = 295 bits (754), Expect = 7e-79 Identities = 179/453 (39%), Positives = 249/453 (54%), Gaps = 1/453 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L D V A +E E RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 LKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E + R FG + VNVQP+S AN+AVY +L D ++G+ Sbjct: 64 CEHVDVVEDIARDRVKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + + Y V+ ++ I+YD + +A + PK+++ G S+ Sbjct: 120 GGHLTHG------SPVNFSGVQYNFVEYGVDAESHCINYDDVLAKAKEHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF R R IAD+ GA LM DMAHI+GLVAA +P + VT+TTHK LRGPRG Sbjct: 174 YPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + F +I+ ++FP +QGGP + IAA A+ + Sbjct: 234 GMILCEE-------------------QFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 ++K Y Q ++ NA LA L + LV+GGTDNHL+L D+R +TGK E V + Sbjct: 275 QDDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEV 334 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I++NK I + S GVRIGT A+T+RG +D + IA + LK H Sbjct: 335 GITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEDMDEIASLI-------AYTLKNH 387 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 EN + E +VEA S+F M Sbjct: 388 -----------ENEAALEEARKRVEALTSKFPM 409
>Q47IH1:GLYA_DECAR Serine hydroxymethyltransferase - Dechloromonas aromatica (strain| RCB) Length = 416 Score = 294 bits (753), Expect = 9e-79 Identities = 174/405 (42%), Positives = 236/405 (58%), Gaps = 3/405 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 LA+ DP++ ++ E RQ IELIASEN+V +AV++A GS LTNKY+EG+PG RYYGG Sbjct: 8 LAKVDPELWQAIQAEVQRQEDHIELIASENYVSKAVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D E++ R FG + A NVQP S + AN AV P D IMG+ Sbjct: 68 CEYVDVAEQIAIDRLKKLFGAEAA----NVQPNSGSQANQAVLMAFAKPGDTIMGMSLAE 123 Query: 991 GGHVSHGY-YTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGS 1167 GGH++HG SGK +F +SY +N + IDYDK+E A + PKI++ G S Sbjct: 124 GGHLTHGMALNMSGK-------WFNVVSYGLNEKEE-IDYDKMEALAREHKPKIIVAGAS 175 Query: 1168 SYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPR 1347 +Y D+ R IA + GA+ DMAH +GL+AA +P + DVVTSTTHK LRGPR Sbjct: 176 AYALRIDWERFAKIAKEVGAIFWVDMAHYAGLIAAGFYPNPVPFADVVTSTTHKTLRGPR 235 Query: 1348 GGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQV 1527 GG+I + + E +N A+FP LQGGP + IAA A+ K+ Sbjct: 236 GGVILMKA-------------------EHEKALNSAIFPGLQGGPLEHVIAAKAVAFKEA 276 Query: 1528 ATPEYKAYIQQVMKNAQALASAL-LRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCE 1704 ATPE+K Y +QV+ NA+ +A L R R+V+G T++H+ L DLR +TGK+ E Sbjct: 277 ATPEFKNYQEQVINNARVMARVLGEERGLRIVSGRTESHVFLLDLRAKNITGKDAEAALG 336 Query: 1705 LCHISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIA 1836 HI++NK I D G+RIG+PAMTTRG E + E IA Sbjct: 337 RAHITVNKNGIPNDPQKPFVTSGIRIGSPAMTTRGFTEIEAEQIA 381
>Q5PBM8:GLYA_ANAMM Serine hydroxymethyltransferase - Anaplasma marginale (strain St.| Maries) Length = 430 Score = 294 bits (753), Expect = 9e-79 Identities = 173/406 (42%), Positives = 232/406 (57%), Gaps = 1/406 (0%) Frame = +1 Query: 619 GNQPLAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGAR 798 GN + D +V M E +RQ +++IASENFV RAVL A GS LTNKY+EG+ G+R Sbjct: 6 GNVDIGVFDAEVANSMSAELERQNTLLQMIASENFVSRAVLQAQGSVLTNKYAEGYAGSR 65 Query: 799 YYGGNQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGL 978 YY G +D +E L +R FG C NVQP+S + AN V+ LL P D I+G+ Sbjct: 66 YYCGCALVDVVENLAVERLCRLFG----CKFANVQPHSGSQANQQVFMALLKPGDTILGM 121 Query: 979 EPPSGGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILIC 1158 GGH++HG + VSG +F ++SY VN TG ID D++E A+ P ++I Sbjct: 122 SLDCGGHLTHG----AAPNVSGR--WFNAVSYGVNRDTGLIDMDEVEALALSAKPSLIIA 175 Query: 1159 GGSSYPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLR 1338 G SSYPR DFA R IADK GA L+ D+AH SGL+A SPF + VVTSTTHK LR Sbjct: 176 GASSYPRRIDFAAFRAIADKVGAYLLADIAHYSGLIAGGCYPSPFGHAHVVTSTTHKTLR 235 Query: 1339 GPRGGIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITL 1518 GPRG +I +D + KI +VFP +QGGP + IAA A+ Sbjct: 236 GPRGAVIM------------------TDDEEIHKKIRLSVFPGMQGGPLMHVIAAKAVAF 277 Query: 1519 KQVATPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKV 1698 K+ P++K Y QQV++N++ LA L +VTGGTD+H+VL DLR+ G+TG+ Sbjct: 278 KEALHPDFKLYAQQVLENSRVLAGVLSSEGLDVVTGGTDSHIVLLDLRSKGVTGREVSSS 337 Query: 1699 CELCHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVI 1833 E I NK + + G+R+G+ A T+RG +FE I Sbjct: 338 LERAGIVCNKNAVPFDTEKPWVTSGIRLGSAAETSRGLGVPEFESI 383
>Q63RB4:GLYA1_BURPS Serine hydroxymethyltransferase 1 - Burkholderia pseudomallei| (Pseudomonas pseudomallei) Length = 415 Score = 294 bits (753), Expect = 9e-79 Identities = 164/406 (40%), Positives = 241/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A DP++ +++E RQ IELIASEN+ AV+ A GS LTNKY+EG+PG RYYGG Sbjct: 9 IANVDPEIWQAIQQENVRQEEHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG + A NVQP S + AN V+ +L P D IMG+ Sbjct: 69 CEYVDIVEQLAIDRVKALFGAEAA----NVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 124 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F +SY +N + IDY+ E A + PK+++ G S+ Sbjct: 125 GGHLTHG------SPVNMSGKWFNVVSYGLN-EAEDIDYEAAEQLAHEHKPKLIVAGASA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 + + DF R+ IA GA LM DMAH +GL+AA +P + D VT+TTHK+LRGPRG Sbjct: 178 FALKIDFERLAKIAKAVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++E +IN A+FP +QGGP + IAA A+ K+ Sbjct: 238 GVILMKA-------------------EYEKQINSAIFPGIQGGPLMHVIAAKAVAFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 +PE+K Y Q+V++NA+ LA L++R R+V+G T++H++L DLR +TGK E Sbjct: 279 SPEFKEYQQKVVENARVLAQTLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGNA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D GVR+G+PAMTTRG + E++ + + Sbjct: 339 HITVNKNAIPNDPEKPFVTSGVRLGSPAMTTRGFGPQEAELVGNLI 384
>Q3JP81:GLYA1_BURP1 Serine hydroxymethyltransferase 1 - Burkholderia pseudomallei (strain| 1710b) Length = 415 Score = 294 bits (753), Expect = 9e-79 Identities = 164/406 (40%), Positives = 241/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A DP++ +++E RQ IELIASEN+ AV+ A GS LTNKY+EG+PG RYYGG Sbjct: 9 IANVDPEIWQAIQQENVRQEEHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG + A NVQP S + AN V+ +L P D IMG+ Sbjct: 69 CEYVDIVEQLAIDRVKALFGAEAA----NVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 124 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F +SY +N + IDY+ E A + PK+++ G S+ Sbjct: 125 GGHLTHG------SPVNMSGKWFNVVSYGLN-EAEDIDYEAAEQLAHEHKPKLIVAGASA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 + + DF R+ IA GA LM DMAH +GL+AA +P + D VT+TTHK+LRGPRG Sbjct: 178 FALKIDFERLAKIAKAVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++E +IN A+FP +QGGP + IAA A+ K+ Sbjct: 238 GVILMKA-------------------EYEKQINSAIFPGIQGGPLMHVIAAKAVAFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 +PE+K Y Q+V++NA+ LA L++R R+V+G T++H++L DLR +TGK E Sbjct: 279 SPEFKEYQQKVVENARVLAQTLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGNA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D GVR+G+PAMTTRG + E++ + + Sbjct: 339 HITVNKNAIPNDPEKPFVTSGVRLGSPAMTTRGFGPQEAELVGNLI 384
>Q62I16:GLYA1_BURMA Serine hydroxymethyltransferase 1 - Burkholderia mallei (Pseudomonas| mallei) Length = 415 Score = 294 bits (753), Expect = 9e-79 Identities = 164/406 (40%), Positives = 241/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 +A DP++ +++E RQ IELIASEN+ AV+ A GS LTNKY+EG+PG RYYGG Sbjct: 9 IANVDPEIWQAIQQENVRQEEHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 68 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D +E+L R FG + A NVQP S + AN V+ +L P D IMG+ Sbjct: 69 CEYVDIVEQLAIDRVKALFGAEAA----NVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 124 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + +F +SY +N + IDY+ E A + PK+++ G S+ Sbjct: 125 GGHLTHG------SPVNMSGKWFNVVSYGLN-EAEDIDYEAAEQLAHEHKPKLIVAGASA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 + + DF R+ IA GA LM DMAH +GL+AA +P + D VT+TTHK+LRGPRG Sbjct: 178 FALKIDFERLAKIAKAVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + ++E +IN A+FP +QGGP + IAA A+ K+ Sbjct: 238 GVILMKA-------------------EYEKQINSAIFPGIQGGPLMHVIAAKAVAFKEAL 278 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 +PE+K Y Q+V++NA+ LA L++R R+V+G T++H++L DLR +TGK E Sbjct: 279 SPEFKEYQQKVVENARVLAQTLVKRGLRIVSGRTESHVMLVDLRAKNITGKAAEAALGNA 338 Query: 1711 HISINKTPIYGD-NGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 HI++NK I D GVR+G+PAMTTRG + E++ + + Sbjct: 339 HITVNKNAIPNDPEKPFVTSGVRLGSPAMTTRGFGPQEAELVGNLI 384
>Q72CT0:GLYA_DESVH Serine hydroxymethyltransferase - Desulfovibrio vulgaris (strain| Hildenborough / ATCC 29579 / NCIMB 8303) Length = 412 Score = 294 bits (752), Expect = 1e-78 Identities = 176/449 (39%), Positives = 243/449 (54%), Gaps = 1/449 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 DP+V + E +RQ +ELIASENFV AV A GS LT+KY+EG+PG RYYGG + + Sbjct: 8 DPEVGKAIILEIERQTGKLELIASENFVSAAVRQAQGSVLTHKYAEGYPGKRYYGGCEFV 67 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D E + +RA T FG C NVQP+S + AN+ VY L P D I+G+ GGH+ Sbjct: 68 DIAENIAIERARTIFG----CEYANVQPHSGSQANMGVYFACLKPGDTILGMNLSHGGHL 123 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG V+ + F + Y V +TG IDY+++ A + P +++ G S+YPR Sbjct: 124 THG------SPVNFSGRLFNVVFYGVEKETGRIDYEQVAALAREHKPSLIVAGASAYPRT 177 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFAR R IAD+ GA LM DMAHI+GLVAA SP + T+TTHK LRGPRGG+I Sbjct: 178 IDFARFRAIADEVGAKLMVDMAHIAGLVAAGYHPSPVQHAHYTTTTTHKTLRGPRGGMIL 237 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 + D +N +FP +QGGP + IAA A+ + P + Sbjct: 238 -------------------STEDNGKTLNSQIFPGIQGGPLMHVIAAKAVAFGEALRPAF 278 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K Y +QV+ NA ALA L LV+GGTDNHL+L DL + +TGK+ E + I++ Sbjct: 279 KEYQKQVVDNAAALAGVLTAAGFDLVSGGTDNHLMLVDLTSKDVTGKDAEIALDKAGITV 338 Query: 1723 NKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQHGKVQ 1899 NK + + GVR+GTPA+TTRG + E + +++ A Sbjct: 339 NKNTVPFETRSPFVTSGVRLGTPALTTRGMKAAEMEKVGGWIVDA--------------- 383 Query: 1900 KEFLRGLENNKDIIELGNQVEAFASQFAM 1986 + N + E+ +VE FA QF + Sbjct: 384 ---IANTTNETRLAEISREVERFARQFPL 409
>Q4A8E1:GLYA_MYCH7 Serine hydroxymethyltransferase - Mycoplasma hyopneumoniae (strain| 7448) Length = 418 Score = 293 bits (751), Expect = 2e-78 Identities = 173/427 (40%), Positives = 251/427 (58%), Gaps = 7/427 (1%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + L+ E RQ IELIASEN+ V+ A G+ L+NKY EG+PG RYYGG I Sbjct: 9 DQQISELINLESKRQNSQIELIASENYASEDVILANGTSLSNKYGEGYPGKRYYGGCTFI 68 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D IE++ +R F ++ A NVQPYS +SAN AV+ LL P D+I+GL+ +GGH+ Sbjct: 69 DQIEKIAIERVKKLFKIEYA----NVQPYSGSSANAAVFAALLKPGDKILGLDLNAGGHL 124 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 SHGY K++ + +F+ +SY ++ + +DY+ +E A+ P ++ICG S+Y R+ Sbjct: 125 SHGY------KINFSGMFYSGISYFLD-ENELLDYEAIEKIALKTKPNLIICGYSAYSRK 177 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DFAR R IADK A L+ D+AHI+GL+AA + SP Y ++TSTT K LRGPRGG+I Sbjct: 178 IDFARFRQIADKVNAFLLADIAHIAGLIAAGQHPSPVGYAHIITSTTQKTLRGPRGGLIL 237 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 + + KI+ VFP +QGGP + IAA A+ K+ P + Sbjct: 238 ------------------TSSKEIAAKIDKVVFPGIQGGPFFHTIAAKAVAFKEALEPWF 279 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWD-LRTFGLTGKNFEKVCELCHIS 1719 K Y Q++KNA AS +++ R+V+ GT+NHL D L ++ L GK + + E +I Sbjct: 280 KEYCAQIVKNAAHFASEFIKKGIRIVSQGTENHLFTIDVLSSYNLNGKQAQILLESVNII 339 Query: 1720 INKTPIYGDNGSISP---GGVRIGTPAMTTRGCLEDDFEVIA---DFLIRATQIAGSVLK 1881 NK I N ++SP G+R+GTPAMT+RG E +F +A DF++R ++ +K Sbjct: 340 TNKNTI--PNDTLSPFVTSGLRLGTPAMTSRGFKEQEFSQMAEIIDFVLRKKELNALEIK 397 Query: 1882 QHGKVQK 1902 + K K Sbjct: 398 EIKKKVK 404
>Q2ST43:GLYA_MYCCT Serine hydroxymethyltransferase - Mycoplasma capricolum subsp.| capricolum (strain California kid / ATCC 27343 / NCTC 10154) Length = 413 Score = 293 bits (751), Expect = 2e-78 Identities = 168/399 (42%), Positives = 236/399 (59%), Gaps = 2/399 (0%) Frame = +1 Query: 664 MERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHIDAIERLC 843 + +E RQ IELIASEN+V +AVL+ GS LTNKY+EG+PG RYYGG + ID IE L Sbjct: 13 LNKELKRQQSHIELIASENYVSQAVLELNGSVLTNKYAEGYPGKRYYGGCEFIDEIESLG 72 Query: 844 HQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHVSHGYYTP 1023 Q A F + A N+QP+S + AN A Y LL P DR++ + +GGH++HGY Sbjct: 73 IQTAKELFHAEHA----NIQPHSGSQANDAAYKALLEPKDRVVAMGLDAGGHLTHGY--- 125 Query: 1024 SGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPREWDFARMR 1203 ++ + ++ Y VN T +DY ++E ++ PK+++ G S+Y R DF + + Sbjct: 126 ---PINFSGYTYDFRFYGVNKDTEQLDYQEIEQIVLEHKPKLIVAGASAYSRIIDFKKFK 182 Query: 1204 LIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIFFRKGKNM 1383 IADK GA LM DMAHI+GLVAA +P +Y D+VT+TTHK LRG RGG+I ++ Sbjct: 183 EIADKVGAYLMVDMAHIAGLVAAGVHPNPMEYADIVTTTTHKTLRGARGGLILCKQ---- 238 Query: 1384 RKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEYKAYIQQV 1563 +F K++ AVFP QGGP N IA L + +T E+K Y +Q+ Sbjct: 239 ---------------EFAKKVDSAVFPGSQGGPLENLIAGKTQALLEASTDEFKEYGKQI 283 Query: 1564 MKNAQALASALLRRKCRLVTGGTDNHLVLWDLR-TFGLTGKNFEKVCELCHISINKTPI- 1737 +KN +ALA+ L RLV GG+DNHL+ D++ T +TGK EK+ E I NK I Sbjct: 284 VKNTKALANVLQENGLRLVAGGSDNHLINVDIKSTLQITGKKAEKILESIGIICNKNMIP 343 Query: 1738 YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRA 1854 + G+R+GTPAMTTRG E++F+ + ++ A Sbjct: 344 FDTEKPFYTSGIRLGTPAMTTRGFKEEEFKQVGLIIVSA 382
>O51547:GLYA_BORBU Serine hydroxymethyltransferase - Borrelia burgdorferi (Lyme disease| spirochete) Length = 417 Score = 293 bits (751), Expect = 2e-78 Identities = 180/429 (41%), Positives = 243/429 (56%), Gaps = 2/429 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D + L+E+E+ R+ IELIASENF + A+GS LTNKY+EG+P RYYGG I Sbjct: 3 DDQIFNLIEKEKLREREHIELIASENFTSLEIRQAVGSILTNKYAEGYPLNRYYGGCSFI 62 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D IE L RA FG A NVQP+S + AN+A L+ P DRI+G++ GGH+ Sbjct: 63 DEIETLAISRAKELFGAKYA----NVQPHSGSQANMAAIMALISPGDRILGMQLSHGGHL 118 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG +V+ + IFF + Y V+ + IDYD++ A D P ++I G SSY RE Sbjct: 119 THG------SRVNFSGIFFNTYFYGVSRDSELIDYDEVLKIAKDCRPNLIIAGASSYSRE 172 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF + R IAD A L+CD+AHI+GL+ A S D + TSTTHK LRGPRGGII Sbjct: 173 IDFKKFREIADDVSAYLLCDIAHIAGLIVAGFHNSSIDVAHLTTSTTHKTLRGPRGGIIL 232 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 GK+ K + + + +N VFP QGGP + IA AI K+ + Sbjct: 233 --SGKDFDK----LVNFNGKEKPLFNAVNSTVFPGTQGGPLVHVIAGKAIAFKEALQESF 286 Query: 1543 KAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHISI 1722 K YI V+KN + +A R+V+GGTDNHL L DL + LTG + EK+ E +I++ Sbjct: 287 KEYIANVIKNTKVMAEYFKSEGFRIVSGGTDNHLFLVDLSSSDLTGADAEKLLESVNITL 346 Query: 1723 NKTPIYGDNGSIS-PGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSV-LKQHGKV 1896 NK I D S S G+RIG A+T+RG E D +A F++RA + + LKQ K Sbjct: 347 NKNAIPFDKKSPSLASGIRIGGAAITSRGLNESDSLNVAKFIVRALKAKSDIELKQIKKE 406 Query: 1897 QKEFLRGLE 1923 F+R + Sbjct: 407 VVRFIRDFD 415
>P66804:GLYA_STAAW Serine hydroxymethyltransferase - Staphylococcus aureus (strain MW2)| Length = 412 Score = 293 bits (750), Expect = 2e-78 Identities = 168/407 (41%), Positives = 238/407 (58%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + D + +ERE RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E + RA FG + VNVQP+S + AN+AVY L D ++G+ Sbjct: 64 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + F+ + Y V+ T I+YD++ A++ PK+++ G S+ Sbjct: 120 GGHLTHG------APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF + + IAD+ A LM DMAHI+GLVAA +P +Y D VT+TTHK LRGPRG Sbjct: 174 YSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ++ +++ I+ +FP +QGGP + IAA A+ + Sbjct: 234 GMILCKE-------------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLR-TFGLTGKNFEKVCEL 1707 +K Y QQV+KNA+ LA AL+ R+V+GGTDNHLV D++ + GLTGK E+ + Sbjct: 275 ENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDS 334 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + G+R+GTPA TTRG E FE +A + Sbjct: 335 VGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKII 381
>Q6G7J7:GLYA_STAAS Serine hydroxymethyltransferase - Staphylococcus aureus (strain| MSSA476) Length = 412 Score = 293 bits (750), Expect = 2e-78 Identities = 168/407 (41%), Positives = 238/407 (58%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + D + +ERE RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E + RA FG + VNVQP+S + AN+AVY L D ++G+ Sbjct: 64 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + F+ + Y V+ T I+YD++ A++ PK+++ G S+ Sbjct: 120 GGHLTHG------APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF + + IAD+ A LM DMAHI+GLVAA +P +Y D VT+TTHK LRGPRG Sbjct: 174 YSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ++ +++ I+ +FP +QGGP + IAA A+ + Sbjct: 234 GMILCKE-------------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLR-TFGLTGKNFEKVCEL 1707 +K Y QQV+KNA+ LA AL+ R+V+GGTDNHLV D++ + GLTGK E+ + Sbjct: 275 ENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDS 334 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + G+R+GTPA TTRG E FE +A + Sbjct: 335 VGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKII 381
>Q6GEW2:GLYA_STAAR Serine hydroxymethyltransferase - Staphylococcus aureus (strain| MRSA252) Length = 412 Score = 293 bits (750), Expect = 2e-78 Identities = 168/407 (41%), Positives = 238/407 (58%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + D + +ERE RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E + RA FG + VNVQP+S + AN+AVY L D ++G+ Sbjct: 64 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + F+ + Y V+ T I+YD++ A++ PK+++ G S+ Sbjct: 120 GGHLTHG------APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF + + IAD+ A LM DMAHI+GLVAA +P +Y D VT+TTHK LRGPRG Sbjct: 174 YSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ++ +++ I+ +FP +QGGP + IAA A+ + Sbjct: 234 GMILCKE-------------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLR-TFGLTGKNFEKVCEL 1707 +K Y QQV+KNA+ LA AL+ R+V+GGTDNHLV D++ + GLTGK E+ + Sbjct: 275 ENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDS 334 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + G+R+GTPA TTRG E FE +A + Sbjct: 335 VGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKII 381
>P99091:GLYA_STAAN Serine hydroxymethyltransferase - Staphylococcus aureus (strain N315)| Length = 412 Score = 293 bits (750), Expect = 2e-78 Identities = 168/407 (41%), Positives = 238/407 (58%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + D + +ERE RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E + RA FG + VNVQP+S + AN+AVY L D ++G+ Sbjct: 64 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + F+ + Y V+ T I+YD++ A++ PK+++ G S+ Sbjct: 120 GGHLTHG------APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF + + IAD+ A LM DMAHI+GLVAA +P +Y D VT+TTHK LRGPRG Sbjct: 174 YSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ++ +++ I+ +FP +QGGP + IAA A+ + Sbjct: 234 GMILCKE-------------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLR-TFGLTGKNFEKVCEL 1707 +K Y QQV+KNA+ LA AL+ R+V+GGTDNHLV D++ + GLTGK E+ + Sbjct: 275 ENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDS 334 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + G+R+GTPA TTRG E FE +A + Sbjct: 335 VGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKII 381
>P66803:GLYA_STAAM Serine hydroxymethyltransferase - Staphylococcus aureus (strain Mu50| / ATCC 700699) Length = 412 Score = 293 bits (750), Expect = 2e-78 Identities = 168/407 (41%), Positives = 238/407 (58%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + D + +ERE RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E + RA FG + VNVQP+S + AN+AVY L D ++G+ Sbjct: 64 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + F+ + Y V+ T I+YD++ A++ PK+++ G S+ Sbjct: 120 GGHLTHG------APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF + + IAD+ A LM DMAHI+GLVAA +P +Y D VT+TTHK LRGPRG Sbjct: 174 YSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ++ +++ I+ +FP +QGGP + IAA A+ + Sbjct: 234 GMILCKE-------------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLR-TFGLTGKNFEKVCEL 1707 +K Y QQV+KNA+ LA AL+ R+V+GGTDNHLV D++ + GLTGK E+ + Sbjct: 275 ENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDS 334 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + G+R+GTPA TTRG E FE +A + Sbjct: 335 VGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKII 381
>Q5HE87:GLYA_STAAC Serine hydroxymethyltransferase - Staphylococcus aureus (strain COL)| Length = 412 Score = 293 bits (750), Expect = 2e-78 Identities = 168/407 (41%), Positives = 238/407 (58%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + D + +ERE RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E + RA FG + VNVQP+S + AN+AVY L D ++G+ Sbjct: 64 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + F+ + Y V+ T I+YD++ A++ PK+++ G S+ Sbjct: 120 GGHLTHG------APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF + + IAD+ A LM DMAHI+GLVAA +P +Y D VT+TTHK LRGPRG Sbjct: 174 YSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ++ +++ I+ +FP +QGGP + IAA A+ + Sbjct: 234 GMILCKE-------------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLR-TFGLTGKNFEKVCEL 1707 +K Y QQV+KNA+ LA AL+ R+V+GGTDNHLV D++ + GLTGK E+ + Sbjct: 275 ENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDS 334 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + G+R+GTPA TTRG E FE +A + Sbjct: 335 VGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKII 381
>Q630T3:GLYA_BACCZ Serine hydroxymethyltransferase - Bacillus cereus (strain ZK / E33L)| Length = 414 Score = 293 bits (750), Expect = 2e-78 Identities = 178/453 (39%), Positives = 249/453 (54%), Gaps = 1/453 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L D V A +E E RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 5 LKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 64 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E + R FG + VNVQP+S AN+AVY +L D ++G+ Sbjct: 65 CEHVDVVEDIARDRVKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSH 120 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + + Y V+ ++ I+YD + +A + PK+++ G S+ Sbjct: 121 GGHLTHG------SPVNFSGVQYNFVEYGVDAESHRINYDDVLAKAKEHKPKLIVAGASA 174 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF R R IAD+ GA LM DMAHI+GLVAA +P + VT+TTHK LRGPRG Sbjct: 175 YPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRG 234 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + F +I+ ++FP +QGGP + IAA A+ + Sbjct: 235 GMILCEE-------------------QFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEAL 275 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 ++K Y Q ++ NA LA L + LV+GGTDNHL+L D+R +TGK E V + Sbjct: 276 QDDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEV 335 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I++NK I + S GVRIGT A+T+RG ++ + IA + LK H Sbjct: 336 GITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEEMDEIASLI-------AYTLKNH 388 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 EN + E +VEA S+F M Sbjct: 389 -----------ENEAALEEARKRVEALTSKFPM 410
>Q72XD7:GLYA_BACC1 Serine hydroxymethyltransferase - Bacillus cereus (strain ATCC 10987)| Length = 413 Score = 293 bits (750), Expect = 2e-78 Identities = 178/453 (39%), Positives = 249/453 (54%), Gaps = 1/453 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L D V A +E E RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 LKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +H+D +E + R FG + VNVQP+S AN+AVY +L D ++G+ Sbjct: 64 CEHVDVVEDIARDRVKEIFGAEH----VNVQPHSGAQANMAVYFTILEQGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + + + + Y V+ ++ I+YD + +A + PK+++ G S+ Sbjct: 120 GGHLTHG------SPVNFSGVQYNFVEYGVDAESHRINYDDVLAKAKEHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 YPR DF R R IAD+ GA LM DMAHI+GLVAA +P + VT+TTHK LRGPRG Sbjct: 174 YPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I + F +I+ ++FP +QGGP + IAA A+ + Sbjct: 234 GMILCEE-------------------QFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 ++K Y Q ++ NA LA L + LV+GGTDNHL+L D+R +TGK E V + Sbjct: 275 QDDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEV 334 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFLIRATQIAGSVLKQH 1887 I++NK I + S GVRIGT A+T+RG ++ + IA + LK H Sbjct: 335 GITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEEMDEIASLI-------AYTLKNH 387 Query: 1888 GKVQKEFLRGLENNKDIIELGNQVEAFASQFAM 1986 EN + E +VEA S+F M Sbjct: 388 -----------ENEAALEEARKRVEALTSKFPM 409
>Q2YUJ1:GLYA_STAAB Serine hydroxymethyltransferase - Staphylococcus aureus (strain| bovine RF122) Length = 412 Score = 293 bits (749), Expect = 3e-78 Identities = 168/407 (41%), Positives = 238/407 (58%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + D + +ERE RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E + RA FG + VNVQP+S + AN+AVY L D ++G+ Sbjct: 64 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALEMGDTVLGMNLRH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + F+ + Y V+ T I+YD++ A++ PK+++ G S+ Sbjct: 120 GGHLTHG------APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF + + IAD+ A LM DMAHI+GLVAA +P +Y D VT+TTHK LRGPRG Sbjct: 174 YSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ++ +++ I+ +FP +QGGP + IAA A+ + Sbjct: 234 GMILCKE-------------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLR-TFGLTGKNFEKVCEL 1707 +K Y QQV+KNA+ LA AL+ R+V+GGTDNHLV D++ + GLTGK E+ + Sbjct: 275 ENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDS 334 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + G+R+GTPA TTRG E FE +A + Sbjct: 335 VGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKII 381
>Q2FF15:GLYA_STAA3 Serine hydroxymethyltransferase - Staphylococcus aureus (strain| USA300) Length = 412 Score = 293 bits (749), Expect = 3e-78 Identities = 168/407 (41%), Positives = 238/407 (58%), Gaps = 2/407 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 + + D + +ERE RQ IELIASENFV AV++A GS LTNKY+EG+PG RYYGG Sbjct: 4 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 + +D E + RA FG + VNVQP+S + AN+AVY L D ++G+ Sbjct: 64 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGSQANMAVYLVALGMGDTVLGMNLSH 119 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG V+ + F+ + Y V+ T I+YD++ A++ PK+++ G S+ Sbjct: 120 GGHLTHG------APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASA 173 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R DF + + IAD+ A LM DMAHI+GLVAA +P +Y D VT+TTHK LRGPRG Sbjct: 174 YSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRG 233 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 G+I ++ +++ I+ +FP +QGGP + IAA A+ + Sbjct: 234 GMILCKE-------------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEAL 274 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLR-TFGLTGKNFEKVCEL 1707 +K Y QQV+KNA+ LA AL+ R+V+GGTDNHLV D++ + GLTGK E+ + Sbjct: 275 ENNFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDS 334 Query: 1708 CHISINKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 I+ NK I + G+R+GTPA TTRG E FE +A + Sbjct: 335 VGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKII 381
>Q6CZV5:GLYA2_ERWCT Serine hydroxymethyltransferase 2 - Erwinia carotovora subsp.| atroseptica (Pectobacterium atrosepticum) Length = 423 Score = 293 bits (749), Expect = 3e-78 Identities = 176/406 (43%), Positives = 240/406 (59%), Gaps = 1/406 (0%) Frame = +1 Query: 631 LAEADPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGG 810 L E DP++ + E DRQ +ELIASEN+ V+ S TNKY+EG+ G RYY G Sbjct: 8 LTEFDPELADAILHEEDRQETHVELIASENYASPLVMAIQNSVFTNKYAEGYLGKRYYSG 67 Query: 811 NQHIDAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPS 990 +++D ERL +RA F D A NVQP++ AN AV+ L P D +MG+ Sbjct: 68 CEYVDVAERLAIERAKVLFDCDYA----NVQPHAGAQANAAVFLALTNPGDTVMGMNLAQ 123 Query: 991 GGHVSHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSS 1170 GGH++HG PS SG ++ + Y ++ +TG IDYD++E A++ PK+LI G S+ Sbjct: 124 GGHLTHG--NPSN--FSGRH--YKIVPYGLDSETGLIDYDEMERIALETRPKMLIGGFSA 177 Query: 1171 YPREWDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRG 1350 Y R D+ARMR IADK GA+ DMAH++GLVAA E +P VVTSTTHK LRGPRG Sbjct: 178 YSRHKDWARMRTIADKVGAIFWVDMAHVAGLVAAGEYPNPLPQAHVVTSTTHKTLRGPRG 237 Query: 1351 GIIFFRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVA 1530 GII KG++ DF K+N AVFP +QGGP + IAA A+ K+ Sbjct: 238 GII-LAKGQS---------------EDFYKKLNAAVFPGIQGGPLMHVIAAKAVAFKEAL 281 Query: 1531 TPEYKAYIQQVMKNAQALASALLRRKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELC 1710 PE+ Y +QV+ NA+A+A + +R ++V+ GTDNHL+L DL TGK+ + Sbjct: 282 RPEFTVYQRQVVANARAMARIIQQRGYKIVSDGTDNHLLLIDLSAKPYTGKDADAALSDA 341 Query: 1711 HISINKTPIYGDNGS-ISPGGVRIGTPAMTTRGCLEDDFEVIADFL 1845 +I+ NK + D S G+RIGTPA+TTRG + E +A +L Sbjct: 342 YITTNKNSVPNDPRSPFVTSGLRIGTPAVTTRGFGVTECEQLAGWL 387
>Q8DPZ0:GLYA_STRR6 Serine hydroxymethyltransferase - Streptococcus pneumoniae (strain| ATCC BAA-255 / R6) Length = 418 Score = 292 bits (748), Expect = 4e-78 Identities = 165/405 (40%), Positives = 238/405 (58%), Gaps = 2/405 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D D+ + +E +RQ IELIASEN V +AV+ A GS LTNKY+EG+PG RYYGG + Sbjct: 12 DADLWNAIAKEEERQQNNIELIASENVVSKAVMAAQGSILTNKYAEGYPGRRYYGGTDVV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG A NVQP+S + AN A Y L+ P D +MG++ +GGH+ Sbjct: 72 DVVETLAIERAKEIFGAKFA----NVQPHSGSQANCAAYMSLIEPGDTVMGMDLAAGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG VS + + LSY V+P+T +D+D + +A + PK+++ G S+Y + Sbjct: 128 THG------APVSFSGQTYNFLSYSVDPETELLDFDAILKQAQEVKPKLIVAGASAYSQI 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF++ R IAD GA LM DMAHI+GLVAA SP Y + T+TTHK LRGPRGG+I Sbjct: 182 IDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPVPYAHITTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 ND + KIN A+FP +QGGP + +AA A++ K+V P + Sbjct: 242 ------------------TNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFKEVLDPAF 283 Query: 1543 KAYIQQVMKNAQALASALLR-RKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHIS 1719 K Y V+KN++A+A L+ R+++GGT+NHL L D+ GK + + + +I+ Sbjct: 284 KEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQNLLDEVNIT 343 Query: 1720 INKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIR 1851 +NK I Y G+RIG A+T RG E++ +A+ +I+ Sbjct: 344 LNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIK 388
>Q97R16:GLYA_STRPN Serine hydroxymethyltransferase - Streptococcus pneumoniae| Length = 418 Score = 292 bits (748), Expect = 4e-78 Identities = 165/405 (40%), Positives = 238/405 (58%), Gaps = 2/405 (0%) Frame = +1 Query: 643 DPDVHALMERERDRQVRGIELIASENFVCRAVLDALGSHLTNKYSEGHPGARYYGGNQHI 822 D D+ + +E +RQ IELIASEN V +AV+ A GS LTNKY+EG+PG RYYGG + Sbjct: 12 DADLWNAIAKEEERQQNNIELIASENVVSKAVMAAQGSILTNKYAEGYPGRRYYGGTDVV 71 Query: 823 DAIERLCHQRALTAFGLDPACWGVNVQPYSCTSANLAVYTGLLLPNDRIMGLEPPSGGHV 1002 D +E L +RA FG A NVQP+S + AN A Y L+ P D +MG++ SGGH+ Sbjct: 72 DVVETLAIERAKEIFGAKFA----NVQPHSGSQANCAAYMSLIEPGDTVMGMDLASGGHL 127 Query: 1003 SHGYYTPSGKKVSGASIFFESLSYKVNPQTGYIDYDKLEDRAMDFHPKILICGGSSYPRE 1182 +HG VS + + +SY V+P+T +D+D + +A + PK+++ G S+Y + Sbjct: 128 THG------APVSFSGQTYNFVSYSVDPKTELLDFDAILKQAQEVKPKLIVAGASAYSQI 181 Query: 1183 WDFARMRLIADKCGAVLMCDMAHISGLVAAKECRSPFDYCDVVTSTTHKNLRGPRGGIIF 1362 DF++ R IAD GA LM DMAHI+GLVAA SP Y + T+TTHK LRGPRGG+I Sbjct: 182 IDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPVPYAHITTTTTHKTLRGPRGGLIL 241 Query: 1363 FRKGKNMRKRGGSFSQGDENDYDFEDKINFAVFPSLQGGPHNNHIAALAITLKQVATPEY 1542 ND + KIN A+FP +QGGP + +AA A++ K+V P + Sbjct: 242 ------------------TNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFKEVLDPAF 283 Query: 1543 KAYIQQVMKNAQALASALLR-RKCRLVTGGTDNHLVLWDLRTFGLTGKNFEKVCELCHIS 1719 K Y V+KN++A+A L+ R+++GGT+NHL L D+ GK + + + +I+ Sbjct: 284 KEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQNLLDEVNIT 343 Query: 1720 INKTPI-YGDNGSISPGGVRIGTPAMTTRGCLEDDFEVIADFLIR 1851 +NK I Y G+RIG A+T RG E++ +A+ +I+ Sbjct: 344 LNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIK 388 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 346,797,524 Number of extensions: 7668233 Number of successful extensions: 23505 Number of sequences better than 10.0: 360 Number of HSP's gapped: 22029 Number of HSP's successfully gapped: 362 Length of query: 758 Length of database: 100,686,439 Length adjustment: 121 Effective length of query: 637 Effective length of database: 67,496,744 Effective search space: 42995425928 Effective search space used: 42995425928 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
