ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf4p02 |
|---|---|
| Clone Library Name | barley_pub |
>Q6DN14:MCTP1_HUMAN Multiple C2 and transmembrane domain-containing protein 1 - Homo| sapiens (Human) Length = 999 Score = 87.4 bits (215), Expect = 3e-16 Identities = 70/284 (24%), Positives = 131/284 (46%), Gaps = 12/284 (4%) Frame = +2 Query: 1049 SKVYLTPKLW--YLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMW 1222 S ++ LW + + +IE +DL D + YVK LG+Q ++++ P +TLNP W Sbjct: 459 SDLHRKSHLWRGIVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMP-KTLNPQW 517 Query: 1223 NEDLMFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEK 1402 E F E + ++ D+ A +DD IGR + L ++R HK L Q E Sbjct: 518 REQFDFHLYEERGGVIDITAWDKDAGKRDDFIGRCQVDLSALSREQTHK-LELQLEEGEG 576 Query: 1403 HVMVDGEQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKH--------- 1555 H++ + + + + D S + D + + L ++ Sbjct: 577 HLV--------------LLVTLTASATVSISDLSVNSLEDQKEREEILKRYSPLRIFHNL 622 Query: 1556 -NIGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTW 1732 ++G L++ ++ A+GL+ D G +DP+CV + + T T+ + P+WN+ +T+ Sbjct: 623 KDVGFLQVKVIRAEGLM---AADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTF 679 Query: 1733 EVHDPCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLE 1864 + D +V+ + V+D E + + D +GKV I L +++ Sbjct: 680 NIKDIHSVLEVTVYD-------EDRDRSADF-LGKVAIPLLSIQ 715 Score = 52.4 bits (124), Expect = 1e-05 Identities = 24/65 (36%), Positives = 41/65 (63%) Frame = +2 Query: 581 VEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSK 760 ++ + +L V+V++A+ L + D+TG DP+ V+L N + T K NPEWN+VF F+ Sbjct: 622 LKDVGFLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNI 681 Query: 761 ERIQA 775 + I + Sbjct: 682 KDIHS 686 Score = 50.8 bits (120), Expect = 3e-05 Identities = 59/253 (23%), Positives = 99/253 (39%), Gaps = 8/253 (3%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFS-KERIQASX 781 + +++ ++L + D G DPYV+ +LG+ K ++ K NP+W + F F E Sbjct: 474 ITLIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYEERGGVI 533 Query: 782 XXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGELMLAVW 961 GR DL+ + + L +LEE GH L+L V Sbjct: 534 DITAWDKDAGKRDDFIGRCQVDLSALSREQTHKLEL-----QLEEGEGH-----LVLLVT 583 Query: 962 MGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLW-------YLRVNVIEAQDLIP 1120 + A + + S+ K Y +++ +L+V VI A+ L+ Sbjct: 584 LTASATVSISDL---SVNSLEDQKEREEILKRYSPLRIFHNLKDVGFLQVKVIRAEGLMA 640 Query: 1121 NDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAP 1300 D T + + L N L T + + LNP WN+ F + L ++V D Sbjct: 641 ADVTGKSDPFCVVELNNDRLLTH-TVYKNLNPEWNKVFTF-NIKDIHSVLEVTVYDEDRD 698 Query: 1301 GKDDVIGRTVISL 1339 D +G+ I L Sbjct: 699 RSADFLGKVAIPL 711 Score = 45.8 bits (107), Expect = 0.001 Identities = 37/149 (24%), Positives = 70/149 (46%) Frame = +2 Query: 1544 LWKHNIGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQ 1723 LW+ G++ + ++ + L K D G +DPY + G + +++ + + P+W EQ Sbjct: 467 LWR---GIVSITLIEGRDL---KAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQ 520 Query: 1724 YTWEVHDPCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLIV 1903 + + +++ GV D + +K G RD IG+ ++ LS L R TH L + Sbjct: 521 FDFHLYEE----RGGVID---ITAWDKDAGKRDDFIGRCQVDLSAL--SREQTHKLELQL 571 Query: 1904 LTPAGVKKMGEVQLAVRFTCSSLLNMMTL 1990 + G + L V T S+ +++ L Sbjct: 572 -----EEGEGHLVLLVTLTASATVSISDL 595 Score = 37.4 bits (85), Expect = 0.38 Identities = 26/123 (21%), Positives = 55/123 (44%) Frame = +1 Query: 2335 YNLPLLFLIGVWYYRWRSRQPPHMDTRLSHAETAHPDELDEEFDTFPTSRPPDIVRMRYD 2514 Y +PL+ L+ + + + R + E DE +E+ S + Y Sbjct: 824 YMIPLVLLLLLTWNYFLIISGKDNRQRDTVVEDMLEDEEEEDDKDDKDSEKKGFINKIY- 882 Query: 2515 RLRSVAGRIQTVVGDLATQGERLQSLLSWRDPRATALFVTFCFIAAIVLYVTPFRVVVFL 2694 ++ V +Q ++ ++A+ GER+++ +W P + L + + +LY P R +V + Sbjct: 883 AIQEVCVSVQNILDEVASFGERIKNTFNWTVPFLSWLAIVALCVFTAILYCIPLRYIVLV 942 Query: 2695 AGL 2703 G+ Sbjct: 943 WGI 945 Score = 33.5 bits (75), Expect = 5.5 Identities = 22/91 (24%), Positives = 40/91 (43%) Frame = +2 Query: 1067 PKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVA 1246 P ++ L + + Q L D+ + YVK +G + + + LNP+W E+ + Sbjct: 258 PGMYQLDITLRRGQSLAARDRGGTSDPYVKFKIGGKEVFRSKIIHKNLNPVW-EEKACIL 316 Query: 1247 AEPFEEHLILSVEDRIAPGKDDVIGRTVISL 1339 + E L + V D +DD +G + L Sbjct: 317 VDHLREPLYIKVFDYDFGLQDDFMGSAFLDL 347 Score = 33.5 bits (75), Expect = 5.5 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 1/105 (0%) Frame = +2 Query: 1562 GVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWV-RTRTIIDSFTPKWNEQYTWEV 1738 G+ +L I +G + +D GT+DPY K G K V R++ I + P W E+ V Sbjct: 259 GMYQLDITLRRGQ-SLAARDRGGTSDPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACILV 317 Query: 1739 HDPCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDR 1873 + I VFD G +D +G + L+ LE +R Sbjct: 318 DHLREPLYIKVFDYDF--------GLQDDFMGSAFLDLTQLELNR 354
>Q9R0N7:SYT7_MOUSE Synaptotagmin-7 - Mus musculus (Mouse)| Length = 403 Score = 66.2 bits (160), Expect = 8e-10 Identities = 68/264 (25%), Positives = 112/264 (42%), Gaps = 14/264 (5%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFS 757 Q L V+V+KA+ELP+KD +G+ DP+V++ L +K T+ K NP WN+ F F Sbjct: 148 QESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFE 207 Query: 758 ----KERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEE-RN 922 ++ +Q G V LN+V + + W L+ + Sbjct: 208 GFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDL-----TQMQTFWKDLKPCSD 262 Query: 923 GHKVKGELMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIE 1102 G +GEL+L++ A+ + VN+I+ Sbjct: 263 GSGSRGELLLSLCYNPSANS---------------------------------IIVNIIK 289 Query: 1103 AQDLIPNDKTRFPEVYVKAMLGNQALRTR----VSPGRTLNPMWNEDLMF-VAAEPFEE- 1264 A++L D + YVK L + R V+ R LNP++NE F + E E Sbjct: 290 ARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFAFDIPTEKLRET 349 Query: 1265 HLILSVEDRIAPGKDDVIGRTVIS 1336 +I++V D+ ++DVIG+ +S Sbjct: 350 TIIITVMDKDKLSRNDVIGKIYLS 373 Score = 37.0 bits (84), Expect = 0.50 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 7/87 (8%) Frame = +2 Query: 515 KETTPHLGGAAAGDKLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYK 694 K+ P G+ + +L + + V ++KA+ L + D+ G+ DPYV+V L YK Sbjct: 255 KDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWL-MYK 313 Query: 695 GTTRHFEKKT-------NPEWNQVFAF 754 R +KKT NP +N+ FAF Sbjct: 314 -DKRVEKKKTVTKKRNLNPIFNESFAF 339 Score = 35.0 bits (79), Expect = 1.9 Identities = 42/141 (29%), Positives = 62/141 (43%), Gaps = 7/141 (4%) Frame = +2 Query: 947 MLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPND 1126 ML + G++ DEA H + + L I+ V + L V V++AQ+L D Sbjct: 115 MLMLSPGSEEDEA-----HEGCSR---ENLGRIQFSVGYNFQESTLTVKVMKAQELPAKD 166 Query: 1127 KTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEE----HLILSVE 1285 + + +VK L L T+V + LNP WNE +F P+E+ L L V Sbjct: 167 FSGTSDPFVKIYLLPDKKHKLETKVKR-KNLNPHWNETFLF-EGFPYEKVVQRVLYLQVL 224 Query: 1286 DRIAPGKDDVIGRTVISLQHV 1348 D ++D IG I L V Sbjct: 225 DYDRFSRNDPIGEVSIPLNKV 245
>P40748:SYT3_RAT Synaptotagmin-3 - Rattus norvegicus (Rat)| Length = 588 Score = 66.2 bits (160), Expect = 8e-10 Identities = 84/296 (28%), Positives = 122/296 (41%), Gaps = 20/296 (6%) Frame = +2 Query: 494 RPEEYSLKETTPHLGGAAAGDKLTTTYDLVEQMQYLY------VRVVKAKELPSKDLTGS 655 +PE Y G +G+ + ++YLY VR+++A +LP+KD G Sbjct: 273 KPELYQGTGPGGRRTGGGSGEAGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGF 332 Query: 656 CDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFS---KERIQASXXXXXXXXXXXXX 817 DPYV++ L K T+ K NP +N+ F FS E Q Sbjct: 333 SDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPLAELAQRKLHFSVYDFDRFSR 392 Query: 818 XXXXGRVMFD-LNEVPKRVPPDSPLAPQWYRLEERNGHKVK-GELMLAVWMGTQADEAFP 991 G+V+ D L E+ ++ PPD PL W + E K GEL ++ Sbjct: 393 HDLIGQVVLDNLLELAEQ-PPDRPL---WRDILEGGSEKADLGELNFSL----------- 437 Query: 992 EAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGN 1171 +P GL L V +I+A +L D T F + YVKA L + Sbjct: 438 -------CYLPTAGL---------------LTVTIIKASNLKAMDLTGFSDPYVKASLIS 475 Query: 1172 QALRTRVS----PGRTLNPMWNEDLMF-VAAEPFEE-HLILSVEDRIAPGKDDVIG 1321 + R + TLNP +NE L+F VA E E L ++V D G ++VIG Sbjct: 476 EGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIG 531
>Q9BQG1:SYT3_HUMAN Synaptotagmin-3 - Homo sapiens (Human)| Length = 590 Score = 65.9 bits (159), Expect = 1e-09 Identities = 75/263 (28%), Positives = 108/263 (41%), Gaps = 19/263 (7%) Frame = +2 Query: 590 MQYLY------VRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQ 742 ++YLY VR+++A +LP+KD G DPYV++ L K T+ K NP +N+ Sbjct: 307 LRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNE 366 Query: 743 VFAFS---KERIQASXXXXXXXXXXXXXXXXXGRVMFD-LNEVPKRVPPDSPLAPQWYRL 910 F FS E Q G+V+ D L E+ ++ PPD PL W + Sbjct: 367 TFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQ-PPDRPL---WRDI 422 Query: 911 EERNGHKVKGELMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRV 1090 E K L + + P L V Sbjct: 423 VEGGSEKA--------------------------------DLGELNFSLCYLPTAGRLTV 450 Query: 1091 NVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVS----PGRTLNPMWNEDLMF-VAAEP 1255 +I+A +L D T F + YVKA L ++ R + TLNP +NE L+F VA E Sbjct: 451 TIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPES 510 Query: 1256 FEE-HLILSVEDRIAPGKDDVIG 1321 E L ++V D G ++VIG Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIG 533
>O35681:SYT3_MOUSE Synaptotagmin-3 - Mus musculus (Mouse)| Length = 587 Score = 65.5 bits (158), Expect = 1e-09 Identities = 73/255 (28%), Positives = 105/255 (41%), Gaps = 13/255 (5%) Frame = +2 Query: 596 YLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFS--- 757 +L VR+++A +LP+KD G DPYV++ L K T+ K NP +N+ F FS Sbjct: 312 HLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPL 371 Query: 758 KERIQASXXXXXXXXXXXXXXXXXGRVMFD-LNEVPKRVPPDSPLAPQWYRLEERNGHKV 934 E Q G+V+ D L E+ ++ PPD PL W + E K Sbjct: 372 AELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQ-PPDRPL---WRDILEGGSEKA 427 Query: 935 KGELMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDL 1114 L + + P L V +I+A +L Sbjct: 428 --------------------------------DLGELNFSLCYLPTAGRLTVTIIKASNL 455 Query: 1115 IPNDKTRFPEVYVKAMLGNQALRTRVS----PGRTLNPMWNEDLMF-VAAEPFEE-HLIL 1276 D T F + YVKA L ++ R + TLNP +NE L+F VA E E L + Sbjct: 456 KAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSI 515 Query: 1277 SVEDRIAPGKDDVIG 1321 +V D G ++VIG Sbjct: 516 AVVDYDCIGHNEVIG 530
>Q9Z1X1:FA62A_RAT Protein FAM62A - Rattus norvegicus (Rat)| Length = 1088 Score = 64.7 bits (156), Expect = 2e-09 Identities = 117/533 (21%), Positives = 199/533 (37%), Gaps = 27/533 (5%) Frame = +2 Query: 605 VRVVKAKELPSKD------LTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSKER 766 + ++ A+ L SKD + G DPY V++G +R +++ NP W + + Sbjct: 325 IHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEELNPHWGETYEVIVHE 384 Query: 767 IQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGH-KVKGE 943 + GR+ D+ +V + D+ WY L+ G ++ E Sbjct: 385 VPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGVLDN-----WYPLQGGQGQVHLRLE 439 Query: 944 LMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPN 1123 + + + D+ W+ S P A+I L V + AQDL Sbjct: 440 WLSLLPDAEKLDQVLQ--WNRGITSRPEPPSAAI------------LVVYLDRAQDLPLK 485 Query: 1124 DKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAPG 1303 + P V+ + + ++ + T P+W E F +P + L + V Sbjct: 486 KGNKEPNPMVQLSVQDVTQESKATYS-TNCPVWEEAFRFFLQDPRSQELDVQV------- 537 Query: 1304 KDDVIGRTVISLQHVARRL--DHKLLNSQWYNLEKHVMVDGEQRKETKFSSRI------H 1459 KDD T+ +L RL +L QW+ L R K RI Sbjct: 538 KDDSRALTLGALTLPLARLLTASELTLDQWFQLSSS---GPNSRLYMKLVMRILYLDSSE 594 Query: 1460 LRICLEGGYHVLDES---THYSSDLRP----TAKQLWKHNIGVLELGILTAQGLLPMKTK 1618 +R+ E G D T S D P T VL + +L AQ L+ Sbjct: 595 MRLPTEPGAQDWDSESPETGSSVDAPPRPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRF 654 Query: 1619 DG---RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHD-PCTVITIGVFDNCH 1786 G +G +DPY K + +RT + + P+WNE + V P + I VFD Sbjct: 655 LGGLVKGKSDPYVKLKVAGRSLRTHVVREDLNPRWNEVFEVIVTSIPGQELDIEVFDK-- 712 Query: 1787 LNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLIVLTPAGVKKMGEVQLAVRFTCS 1966 + +D +G+ ++ L+T+ + + + + P+G + +L+ R T + Sbjct: 713 -------DLDKDDFLGRYKVGLTTV-LNSGFLDEWLTLEDVPSGRLHLRLERLSPRPTAA 764 Query: 1967 SLLNMMTLYSQPLLPKMHYVHPLSVIQVDNLRRQATNIVSTRLSRAEP-PLRK 2122 L ++ + S+IQ A ++S L R+E PLRK Sbjct: 765 ELEEVLQVN--------------SLIQTQKSSELAAALLSVYLERSEDLPLRK 803 Score = 47.4 bits (111), Expect = 4e-04 Identities = 94/475 (19%), Positives = 168/475 (35%), Gaps = 41/475 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKD------LTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSK 760 L + V++A++L +KD + G DPYV++K+ T + NP WN+VF Sbjct: 638 LRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGRSLRTHVVREDLNPRWNEVFEVIV 697 Query: 761 ERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKG 940 I GR L V +S +W LE+ ++ Sbjct: 698 TSIPGQELDIEVFDKDLDKDDFLGRYKVGLTTV-----LNSGFLDEWLTLEDVPSGRLHL 752 Query: 941 ELMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIP 1120 L T A+ +S + LA+ VYL ++DL Sbjct: 753 RLERLSPRPTAAELEEVLQVNSLIQTQKSSELAAALLSVYLE-----------RSEDLPL 801 Query: 1121 NDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAP 1300 T+ P Y +G + +T+ + +T P+W E F+ +P E L L V Sbjct: 802 RKGTKPPSPYAILTVGETSHKTK-TVSQTSAPIWEESASFLIRKPHAESLELQVRGE--- 857 Query: 1301 GKDDVIGRTVISLQHVARRLDHKLLNSQWYNLE------KHVMVDGEQRKETKFSSRIHL 1462 +G + L + + + +L +W+ L V + + + + H Sbjct: 858 -GTGTLGSISLPLSELLQ--EEQLCLDRWFALSGQGQVLMRVQLGILVSQHSGVEAHSHS 914 Query: 1463 RICLEGGYHVLDESTHYSSDLRPTAKQL---------------------WKHNIGVLELG 1579 L VL + TH +S + +L W H+ + Sbjct: 915 SSSLNEEPEVLGDPTHTASPVLEVRHRLTHGDSPSEALIGPLGQVKLTVWYHSDEQKLIS 974 Query: 1580 ILTAQGLLPMKTKDGRGTTDPYCVA-----KYGQKWVRTRTIIDSFTPKWNEQYTWEVHD 1744 I+ + L ++GR DPY K +T + P++NE++ W++ Sbjct: 975 IIHSCRAL---RQNGRDLPDPYVSVLLLPDKNRGTKRKTSQKKRTLNPEFNERFEWDLPL 1031 Query: 1745 PCTV---ITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLI 1900 T+ + + V N E+ +GKV++ L+ ++ + Y LI Sbjct: 1032 DGTLRRKLDVSVKSNSSFMSRER------ELLGKVQLDLAEIDLSQGAAQWYDLI 1080 Score = 42.0 bits (97), Expect = 0.015 Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 7/119 (5%) Frame = +2 Query: 1562 GVLELGILTAQGLLPMKTKDG------RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQ 1723 G++ + +L A+GL +KD G +DPY + + G + +R I + P W E Sbjct: 321 GIIRIHLLAARGL---SSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEELNPHWGET 377 Query: 1724 YTWEVHD-PCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPL 1897 Y VH+ P I + VFD + +D +G++++ + + V + YPL Sbjct: 378 YEVIVHEVPGQEIEVEVFDK---------DPDKDDFLGRMKLDVGKVLQAGVLDNWYPL 427
>P47191:SYT1_CHICK Synaptotagmin-1 - Gallus gallus (Chicken)| Length = 424 Score = 64.3 bits (155), Expect = 3e-09 Identities = 78/308 (25%), Positives = 115/308 (37%), Gaps = 21/308 (6%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 K+ + D Q L V +++A ELP+ D+ G+ DPYV+V L K T+ K N Sbjct: 147 KIQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLN 206 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP L Y Sbjct: 207 PVFNEQFTF---------------------------------KVPYSELGGKTLVMAVYD 233 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFPEAWHS--DAASIPGDGLASIRSKVYLTPKLWY 1081 + + H + GE +A M T E W A + L I + P Sbjct: 234 FDRFSKHDIIGEYKVA--MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGK 291 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPG----RTLNPMWNEDLMFVAA 1249 L V ++EA++L D + YVK L R + TLNP +NE F Sbjct: 292 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV- 350 Query: 1250 EPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWYN 1393 PFE+ ++++V D GK+D IG+ + L H L N +QW+ Sbjct: 351 -PFEQIQKVQIVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHT 409 Query: 1394 LEKHVMVD 1417 L+ VD Sbjct: 410 LQPEEEVD 417 Score = 43.5 bits (101), Expect = 0.005 Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 12/231 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V +I+A +L D + YVK L + T+V +TLNP++NE F Sbjct: 161 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHR-KTLNPVFNEQFTFKV-- 217 Query: 1253 PFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 P+ E L+++V D K D+IG +++ V D + +W +L+ Sbjct: 218 PYSELGGKTLVMAVYDFDRFSKHDIIGEYKVAMNTV----DFGHVTEEWRDLQ-----SA 268 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 E+ ++ K IC +S PTA G L + IL A+ L Sbjct: 269 EKEEQEKLGD-----IC-------------FSLRYVPTA--------GKLTVVILEAKNL 302 Query: 1601 LPMKTKDGRGTTDPYC---VAKYGQKWVRTRTII--DSFTPKWNEQYTWEV 1738 K D G +DPY + + G++ + +T I ++ P +NE +++EV Sbjct: 303 ---KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV 350
>Q9BSJ8:FA62A_HUMAN Protein FAM62A - Homo sapiens (Human)| Length = 1104 Score = 64.3 bits (155), Expect = 3e-09 Identities = 118/538 (21%), Positives = 203/538 (37%), Gaps = 32/538 (5%) Frame = +2 Query: 605 VRVVKAKELPSKD------LTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSKER 766 + ++ A+ L SKD + G DPY V+LG +R +++ NP+W + + Sbjct: 333 IHLLAARGLSSKDKYVKGLIEGKSDPYALVRLGTQTFCSRVIDEELNPQWGETYEVMVHE 392 Query: 767 IQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGEL 946 + GR+ D+ +V + + + W+ L+ G + + L Sbjct: 393 VPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQ-----ASVLDDWFPLQ---GGQGQVHL 444 Query: 947 MLAVWMGTQADEAFPE---AWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLI 1117 L W+ +D E W+ +S P A+I L V + AQDL Sbjct: 445 RLE-WLSLLSDAEKLEQVLQWNWGVSSRPDPPSAAI------------LVVYLDRAQDLP 491 Query: 1118 PNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIA 1297 + P V+ + + ++ + T P+W E F +P + L + V Sbjct: 492 LKKGNKEPNPMVQLSIQDVTQESK-AVYSTNCPVWEEAFRFFLQDPQSQELDVQV----- 545 Query: 1298 PGKDDVIGRTVISLQHVARRL--DHKLLNSQWYNLEKHVMVDGEQRKETKFSSRI----H 1459 KDD T+ +L RL +L+ QW+ L R K RI Sbjct: 546 --KDDSRALTLGALTLPLARLLTAPELILDQWFQLSSS---GPNSRLYMKLVMRILYLDS 600 Query: 1460 LRICL------EGGYHVLDESTHYSSDL----RP--TAKQLWKHNIGVLELGILTAQGLL 1603 IC G + V E+ S + RP T VL + +L AQ L+ Sbjct: 601 SEICFPTVPGCPGAWDVDSENPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLI 660 Query: 1604 PMKTKDG---RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHD-PCTVITIGV 1771 G +G +DPY K + R+ + + P+WNE + V P + + V Sbjct: 661 AKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEVEV 720 Query: 1772 FDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLIVLTPAGVKKMGEVQLAV 1951 FD + +D +G+ ++RL+T+ + + + + P+G + +L Sbjct: 721 FDK---------DLDKDDFLGRCKVRLTTV-LNSGFLDEWLTLEDVPSGRLHLRLERLTP 770 Query: 1952 RFTCSSLLNMMTLYSQPLLPKMHYVHPLSVIQVDNLRRQATNIVSTRLSRAEP-PLRK 2122 R T + L ++ + S+IQ A ++S + RAE PLRK Sbjct: 771 RPTAAELEEVLQVN--------------SLIQTQKSAELAAALLSIYMERAEDLPLRK 814 Score = 54.7 bits (130), Expect = 2e-06 Identities = 94/420 (22%), Positives = 161/420 (38%), Gaps = 35/420 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSKERIQAS 778 L V + +A++LP K +P V++ + + ++ P W + F F + Q+ Sbjct: 480 LVVYLDRAQDLPLKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFRFFLQDPQSQ 539 Query: 779 XXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGH-KVKGELMLA 955 G + L + + + QW++L + ++ +L++ Sbjct: 540 ELDVQVKDDSRALTL--GALTLPLARL---LTAPELILDQWFQLSSSGPNSRLYMKLVMR 594 Query: 956 VWMGTQADEAFPE------AWHSDAASIP-GDGLASIRSKVYLTPKLWY-----LRVNVI 1099 + ++ FP AW D+ + G + + + TP + LR++V+ Sbjct: 595 ILYLDSSEICFPTVPGCPGAWDVDSENPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVL 654 Query: 1100 EAQDLIPNDK------TRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFE 1261 EAQDLI D+ + YVK L ++ R+ V LNP WNE + Sbjct: 655 EAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVR-EDLNPRWNEVFEVIVTSVPG 713 Query: 1262 EHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQRKETK 1441 + L + V D+ KDD +GR + L V L+ L+ +W LE Sbjct: 714 QELEVEVFDKDLD-KDDFLGRCKVRLTTV---LNSGFLD-EWLTLEDVP----------- 757 Query: 1442 FSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILT--------AQG 1597 S R+HLR L+ T RPTA +L + VL++ L A Sbjct: 758 -SGRLHLR---------LERLTP-----RPTAAELEE----VLQVNSLIQTQKSAELAAA 798 Query: 1598 LLP--------MKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDPCT 1753 LL + + G PY G +T+TI + P W+E ++ + P T Sbjct: 799 LLSIYMERAEDLPLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASFLIRKPHT 858 Score = 41.6 bits (96), Expect = 0.020 Identities = 36/146 (24%), Positives = 66/146 (45%), Gaps = 7/146 (4%) Frame = +2 Query: 1562 GVLELGILTAQGLLPMKTKDG------RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQ 1723 G++ + +L A+GL +KD G +DPY + + G + +R I + P+W E Sbjct: 329 GIIRIHLLAARGL---SSKDKYVKGLIEGKSDPYALVRLGTQTFCSRVIDEELNPQWGET 385 Query: 1724 YTWEVHD-PCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLI 1900 Y VH+ P I + VFD + +D +G++++ + + V +PL Sbjct: 386 YEVMVHEVPGQEIEVEVFDK---------DPDKDDFLGRMKLDVGKVLQASVLDDWFPL- 435 Query: 1901 VLTPAGVKKMGEVQLAVRFTCSSLLN 1978 + G+ Q+ +R SLL+ Sbjct: 436 --------QGGQGQVHLRLEWLSLLS 453
>Q3U7R1:FA62A_MOUSE Protein FAM62A - Mus musculus (Mouse)| Length = 1092 Score = 63.9 bits (154), Expect = 4e-09 Identities = 118/533 (22%), Positives = 194/533 (36%), Gaps = 27/533 (5%) Frame = +2 Query: 605 VRVVKAKELPSKD------LTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSKER 766 + ++ A+ L SKD + G DPY V++G +R +++ NP W + + Sbjct: 323 IHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEELNPHWGETYEVIVHE 382 Query: 767 IQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGH-KVKGE 943 + GR+ D+ +V + + + WY L+ G ++ E Sbjct: 383 VPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQ-----AGVLDNWYPLQGGQGQVHLRLE 437 Query: 944 LMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPN 1123 + + + D+ W+ S P A+I L V + AQDL Sbjct: 438 WLSLLPDAEKLDQVL--QWNRGITSRPEPPSAAI------------LVVYLDRAQDLPLK 483 Query: 1124 DKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAPG 1303 + P V+ + R + T +P+W E F +P + L + V Sbjct: 484 KGNKEPNPMVQLSV-QDVTRESKATYSTNSPVWEEAFRFFLQDPRSQELDVQV------- 535 Query: 1304 KDDVIGRTVISLQHVARRL--DHKLLNSQWYNLEKHVMVDGEQRKETKFSSRI------H 1459 KDD T+ +L RL +L QW+ L R K RI Sbjct: 536 KDDSRALTLGALTLPLARLLTASELTLDQWFQLSSS---GPNSRLYMKLVMRILYLDYSE 592 Query: 1460 LRICLEGGYHVLDE---STHYSSDLRP----TAKQLWKHNIGVLELGILTAQGLLPMKTK 1618 +R G D T S D P T VL + +L AQ L+ Sbjct: 593 IRFPTVPGAQDWDRESLETGSSVDAPPRPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRF 652 Query: 1619 DG---RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHD-PCTVITIGVFDNCH 1786 G +G +DPY K K RT + + P+WNE + V P + I VFD Sbjct: 653 LGGLVKGKSDPYVKLKVAGKSFRTHVVREDLNPRWNEVFEVIVTSIPGQELEIEVFDK-- 710 Query: 1787 LNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLIVLTPAGVKKMGEVQLAVRFTCS 1966 + +D +G+ ++ L+T+ + + + + P+G + +L R T + Sbjct: 711 -------DLDKDDFLGRYKVSLTTV-LNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAA 762 Query: 1967 SLLNMMTLYSQPLLPKMHYVHPLSVIQVDNLRRQATNIVSTRLSRAEP-PLRK 2122 L ++ + S+IQ A ++S L RAE PLRK Sbjct: 763 ELEEVLQVN--------------SLIQTQKSSELAAALLSVFLERAEDLPLRK 801 Score = 53.9 bits (128), Expect = 4e-06 Identities = 91/416 (21%), Positives = 160/416 (38%), Gaps = 33/416 (7%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSKERIQAS 778 L V + +A++LP K +P V++ + + ++ +P W + F F + ++ Sbjct: 470 LVVYLDRAQDLPLKKGNKEPNPMVQLSVQDVTRESKATYSTNSPVWEEAFRFFLQDPRSQ 529 Query: 779 XXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGH-KVKGELMLA 955 G + L + + QW++L + ++ +L++ Sbjct: 530 ELDVQVKDDSRALTL--GALTLPLARL---LTASELTLDQWFQLSSSGPNSRLYMKLVMR 584 Query: 956 VWMGTQADEAFP-----EAWHSDAASIPGDGLASIRSKVYLTPKLWY-----LRVNVIEA 1105 + ++ FP + W ++ G + + + TP + LR++V+EA Sbjct: 585 ILYLDYSEIRFPTVPGAQDWDRESLET-GSSVDAPPRPYHTTPNSHFGTENVLRIHVLEA 643 Query: 1106 QDLIPNDK------TRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEH 1267 QDLI D+ + YVK + ++ RT V LNP WNE + + Sbjct: 644 QDLIAKDRFLGGLVKGKSDPYVKLKVAGKSFRTHVVR-EDLNPRWNEVFEVIVTSIPGQE 702 Query: 1268 LILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQRKETKFS 1447 L + V D+ KDD +GR +SL V L+ L+ +W LE S Sbjct: 703 LEIEVFDKDLD-KDDFLGRYKVSLTTV---LNSGFLD-EWLTLEDVP------------S 745 Query: 1448 SRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILT--------AQGLL 1603 R+HLR L+ T RPTA +L + VL++ L A LL Sbjct: 746 GRLHLR---------LERLTP-----RPTAAELEE----VLQVNSLIQTQKSSELAAALL 787 Query: 1604 P--------MKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDP 1747 + + G PY G+ +T+T+ S P W E ++ + P Sbjct: 788 SVFLERAEDLPLRKGTKPPSPYATITVGETSHKTKTVSQSSAPVWEESASFLIRKP 843 Score = 42.0 bits (97), Expect = 0.015 Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 7/119 (5%) Frame = +2 Query: 1562 GVLELGILTAQGLLPMKTKDG------RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQ 1723 G++ + +L A+GL +KD G +DPY + + G + +R I + P W E Sbjct: 319 GIIRIHLLAARGL---SSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEELNPHWGET 375 Query: 1724 YTWEVHD-PCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPL 1897 Y VH+ P I + VFD + +D +G++++ + + V + YPL Sbjct: 376 YEVIVHEVPGQEIEVEVFDK---------DPDKDDFLGRMKLDVGKVLQAGVLDNWYPL 425
>O43581:SYT7_HUMAN Synaptotagmin-7 - Homo sapiens (Human)| Length = 402 Score = 63.2 bits (152), Expect = 6e-09 Identities = 66/264 (25%), Positives = 111/264 (42%), Gaps = 14/264 (5%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFS 757 Q L ++++KA+ELP+KD +G+ DP+V++ L +K T+ K NP WN+ F F Sbjct: 147 QESTLTLKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLKTKVKRKNLNPHWNETFLFE 206 Query: 758 ----KERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEE-RN 922 ++ +Q G V LN+V + + W L+ + Sbjct: 207 GFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDL-----TQMQTFWKDLKPCSD 261 Query: 923 GHKVKGELMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIE 1102 G +GEL+L++ A+ + VN+I+ Sbjct: 262 GSGSRGELLLSLCYNPSANS---------------------------------IIVNIIK 288 Query: 1103 AQDLIPNDKTRFPEVYVKAMLGNQALRTR----VSPGRTLNPMWNEDLMF-VAAEPFEE- 1264 A++L D + YVK L + R V+ R LNP +NE F + E E Sbjct: 289 ARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPNFNESFAFDIPTEKLRET 348 Query: 1265 HLILSVEDRIAPGKDDVIGRTVIS 1336 +I++V D+ ++DVIG+ +S Sbjct: 349 TIIITVMDKDKLSRNDVIGKIYLS 372 Score = 38.1 bits (87), Expect = 0.22 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 5/85 (5%) Frame = +2 Query: 515 KETTPHLGGAAAGDKLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---- 682 K+ P G+ + +L + + V ++KA+ L + D+ G+ DPYV+V L Sbjct: 254 KDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKD 313 Query: 683 -GNYKGTTRHFEKKTNPEWNQVFAF 754 K T ++ NP +N+ FAF Sbjct: 314 KRVEKKKTVTMKRNLNPNFNESFAF 338 Score = 36.6 bits (83), Expect = 0.65 Identities = 76/313 (24%), Positives = 125/313 (39%), Gaps = 15/313 (4%) Frame = +2 Query: 947 MLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPND 1126 ML + G++ DEA H + + L I+ V + L + +++AQ+L D Sbjct: 114 MLMLSPGSEEDEA-----HEGCSR---ENLGRIQFSVGYNFQESTLTLKIMKAQELPAKD 165 Query: 1127 KTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEE----HLILSVE 1285 + + +VK L L+T+V + LNP WNE +F P+E+ L L V Sbjct: 166 FSGTSDPFVKIYLLPDKKHKLKTKVKR-KNLNPHWNETFLF-EGFPYEKVVQRILYLQVL 223 Query: 1286 DRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQRKETKFSSRIHLR 1465 D ++D IG I L ++D + + W +L+ DG + + L Sbjct: 224 DYDRFSRNDPIGEVSIPL----NKVDLTQMQTFWKDLKP--CSDGSGSR-----GELLLS 272 Query: 1466 ICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGLLPMKTKDGRGTTDPY 1645 +C P+A + + I+ A+ L K D GT+DPY Sbjct: 273 LC-----------------YNPSANS--------IIVNIIKARNL---KAMDIGGTSDPY 304 Query: 1646 CVA--KYGQKWV---RTRTIIDSFTPKWNEQYTWEVHDPC---TVITIGVFDNCHLNGGE 1801 Y K V +T T+ + P +NE + +++ T I I V D L Sbjct: 305 VKVWLMYKDKRVEKKKTVTMKRNLNPNFNESFAFDIPTEKLRETTIIITVMDKDKL---- 360 Query: 1802 KANGARDTRIGKV 1840 +R+ IGK+ Sbjct: 361 ----SRNDVIGKI 369
>P21707:SYT1_RAT Synaptotagmin-1 - Rattus norvegicus (Rat)| Length = 421 Score = 62.8 bits (151), Expect = 8e-09 Identities = 78/308 (25%), Positives = 114/308 (37%), Gaps = 21/308 (6%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V +++A ELP+ D+ G+ DPYV+V L K T+ K N Sbjct: 144 KLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLN 203 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP L Y Sbjct: 204 PVFNEQFTF---------------------------------KVPYSELGGKTLVMAVYD 230 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFPEAWHS--DAASIPGDGLASIRSKVYLTPKLWY 1081 + + H + GE + M T E W A + L I + P Sbjct: 231 FDRFSKHDIIGEFKVP--MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGK 288 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPG----RTLNPMWNEDLMFVAA 1249 L V ++EA++L D + YVK L R + TLNP +NE F Sbjct: 289 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV- 347 Query: 1250 EPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWYN 1393 PFE+ ++++V D GK+D IG+ + L H L N +QW+ Sbjct: 348 -PFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHT 406 Query: 1394 LEKHVMVD 1417 L+ VD Sbjct: 407 LQVEEEVD 414 Score = 43.1 bits (100), Expect = 0.007 Identities = 60/231 (25%), Positives = 99/231 (42%), Gaps = 12/231 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V +I+A +L D + YVK L + T+V +TLNP++NE F Sbjct: 158 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHR-KTLNPVFNEQFTFKV-- 214 Query: 1253 PFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 P+ E L+++V D K D+IG + + V D + +W +L+ Sbjct: 215 PYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV----DFGHVTEEWRDLQ-----SA 265 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 E+ ++ K IC +S PTA G L + IL A+ L Sbjct: 266 EKEEQEKLGD-----IC-------------FSLRYVPTA--------GKLTVVILEAKNL 299 Query: 1601 LPMKTKDGRGTTDPYC---VAKYGQKWVRTRTII--DSFTPKWNEQYTWEV 1738 K D G +DPY + + G++ + +T I ++ P +NE +++EV Sbjct: 300 ---KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV 347
>Q5R4J5:SYT1_PONPY Synaptotagmin-1 - Pongo pygmaeus (Orangutan)| Length = 419 Score = 62.8 bits (151), Expect = 8e-09 Identities = 78/308 (25%), Positives = 114/308 (37%), Gaps = 21/308 (6%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V +++A ELP+ D+ G+ DPYV+V L K T+ K N Sbjct: 142 KLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLN 201 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP L Y Sbjct: 202 PVFNEQFTF---------------------------------KVPYSELGGKTLVMAVYD 228 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFPEAWHS--DAASIPGDGLASIRSKVYLTPKLWY 1081 + + H + GE + M T E W A + L I + P Sbjct: 229 FDRFSKHDIIGEFKVP--MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGK 286 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPG----RTLNPMWNEDLMFVAA 1249 L V ++EA++L D + YVK L R + TLNP +NE F Sbjct: 287 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKETTIKKNTLNPYYNESFSFEV- 345 Query: 1250 EPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWYN 1393 PFE+ ++++V D GK+D IG+ + L H L N +QW+ Sbjct: 346 -PFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHT 404 Query: 1394 LEKHVMVD 1417 L+ VD Sbjct: 405 LQVEEEVD 412 Score = 42.4 bits (98), Expect = 0.012 Identities = 60/231 (25%), Positives = 98/231 (42%), Gaps = 12/231 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V +I+A +L D + YVK L + T+V +TLNP++NE F Sbjct: 156 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHR-KTLNPVFNEQFTFKV-- 212 Query: 1253 PFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 P+ E L+++V D K D+IG + + V D + +W +L+ Sbjct: 213 PYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV----DFGHVTEEWRDLQ-----SA 263 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 E+ ++ K IC +S PTA G L + IL A+ L Sbjct: 264 EKEEQEKLGD-----IC-------------FSLRYVPTA--------GKLTVVILEAKNL 297 Query: 1601 LPMKTKDGRGTTDPYC---VAKYGQKWVRTRTII--DSFTPKWNEQYTWEV 1738 K D G +DPY + + G++ + T I ++ P +NE +++EV Sbjct: 298 ---KKMDVGGLSDPYVKIHLMQNGKRLKKKETTIKKNTLNPYYNESFSFEV 345
>P46096:SYT1_MOUSE Synaptotagmin-1 - Mus musculus (Mouse)| Length = 421 Score = 62.8 bits (151), Expect = 8e-09 Identities = 78/308 (25%), Positives = 114/308 (37%), Gaps = 21/308 (6%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V +++A ELP+ D+ G+ DPYV+V L K T+ K N Sbjct: 144 KLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLN 203 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP L Y Sbjct: 204 PVFNEQFTF---------------------------------KVPYSELGGKTLVMAVYD 230 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFPEAWHS--DAASIPGDGLASIRSKVYLTPKLWY 1081 + + H + GE + M T E W A + L I + P Sbjct: 231 FDRFSKHDIIGEFKVP--MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGK 288 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPG----RTLNPMWNEDLMFVAA 1249 L V ++EA++L D + YVK L R + TLNP +NE F Sbjct: 289 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV- 347 Query: 1250 EPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWYN 1393 PFE+ ++++V D GK+D IG+ + L H L N +QW+ Sbjct: 348 -PFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHT 406 Query: 1394 LEKHVMVD 1417 L+ VD Sbjct: 407 LQVEEEVD 414 Score = 43.1 bits (100), Expect = 0.007 Identities = 60/231 (25%), Positives = 99/231 (42%), Gaps = 12/231 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V +I+A +L D + YVK L + T+V +TLNP++NE F Sbjct: 158 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHR-KTLNPVFNEQFTFKV-- 214 Query: 1253 PFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 P+ E L+++V D K D+IG + + V D + +W +L+ Sbjct: 215 PYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV----DFGHVTEEWRDLQ-----SA 265 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 E+ ++ K IC +S PTA G L + IL A+ L Sbjct: 266 EKEEQEKLGD-----IC-------------FSLRYVPTA--------GKLTVVILEAKNL 299 Query: 1601 LPMKTKDGRGTTDPYC---VAKYGQKWVRTRTII--DSFTPKWNEQYTWEV 1738 K D G +DPY + + G++ + +T I ++ P +NE +++EV Sbjct: 300 ---KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV 347
>Q60HC0:SYT1_MACFA Synaptotagmin-1 - Macaca fascicularis (Crab eating macaque)| (Cynomolgus monkey) Length = 419 Score = 62.8 bits (151), Expect = 8e-09 Identities = 78/308 (25%), Positives = 114/308 (37%), Gaps = 21/308 (6%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V +++A ELP+ D+ G+ DPYV+V L K T+ K N Sbjct: 142 KLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLN 201 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP L Y Sbjct: 202 PVFNEQFTF---------------------------------KVPYSELGGKTLVMAVYD 228 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFPEAWHS--DAASIPGDGLASIRSKVYLTPKLWY 1081 + + H + GE + M T E W A + L I + P Sbjct: 229 FDRFSKHDIIGEFKVP--MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGK 286 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPG----RTLNPMWNEDLMFVAA 1249 L V ++EA++L D + YVK L R + TLNP +NE F Sbjct: 287 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV- 345 Query: 1250 EPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWYN 1393 PFE+ ++++V D GK+D IG+ + L H L N +QW+ Sbjct: 346 -PFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHT 404 Query: 1394 LEKHVMVD 1417 L+ VD Sbjct: 405 LQVEEEVD 412 Score = 43.1 bits (100), Expect = 0.007 Identities = 60/231 (25%), Positives = 99/231 (42%), Gaps = 12/231 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V +I+A +L D + YVK L + T+V +TLNP++NE F Sbjct: 156 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHR-KTLNPVFNEQFTFKV-- 212 Query: 1253 PFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 P+ E L+++V D K D+IG + + V D + +W +L+ Sbjct: 213 PYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV----DFGHVTEEWRDLQ-----SA 263 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 E+ ++ K IC +S PTA G L + IL A+ L Sbjct: 264 EKEEQEKLGD-----IC-------------FSLRYVPTA--------GKLTVVILEAKNL 297 Query: 1601 LPMKTKDGRGTTDPYC---VAKYGQKWVRTRTII--DSFTPKWNEQYTWEV 1738 K D G +DPY + + G++ + +T I ++ P +NE +++EV Sbjct: 298 ---KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV 345
>P21579:SYT1_HUMAN Synaptotagmin-1 - Homo sapiens (Human)| Length = 422 Score = 62.8 bits (151), Expect = 8e-09 Identities = 78/308 (25%), Positives = 114/308 (37%), Gaps = 21/308 (6%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V +++A ELP+ D+ G+ DPYV+V L K T+ K N Sbjct: 145 KLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLN 204 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP L Y Sbjct: 205 PVFNEQFTF---------------------------------KVPYSELGGKTLVMAVYD 231 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFPEAWHS--DAASIPGDGLASIRSKVYLTPKLWY 1081 + + H + GE + M T E W A + L I + P Sbjct: 232 FDRFSKHDIIGEFKVP--MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGK 289 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPG----RTLNPMWNEDLMFVAA 1249 L V ++EA++L D + YVK L R + TLNP +NE F Sbjct: 290 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV- 348 Query: 1250 EPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWYN 1393 PFE+ ++++V D GK+D IG+ + L H L N +QW+ Sbjct: 349 -PFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHT 407 Query: 1394 LEKHVMVD 1417 L+ VD Sbjct: 408 LQVEEEVD 415 Score = 43.1 bits (100), Expect = 0.007 Identities = 60/231 (25%), Positives = 99/231 (42%), Gaps = 12/231 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V +I+A +L D + YVK L + T+V +TLNP++NE F Sbjct: 159 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHR-KTLNPVFNEQFTFKV-- 215 Query: 1253 PFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 P+ E L+++V D K D+IG + + V D + +W +L+ Sbjct: 216 PYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV----DFGHVTEEWRDLQ-----SA 266 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 E+ ++ K IC +S PTA G L + IL A+ L Sbjct: 267 EKEEQEKLGD-----IC-------------FSLRYVPTA--------GKLTVVILEAKNL 300 Query: 1601 LPMKTKDGRGTTDPYC---VAKYGQKWVRTRTII--DSFTPKWNEQYTWEV 1738 K D G +DPY + + G++ + +T I ++ P +NE +++EV Sbjct: 301 ---KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV 348
>P48018:SYT1_BOVIN Synaptotagmin-1 - Bos taurus (Bovine)| Length = 422 Score = 62.8 bits (151), Expect = 8e-09 Identities = 78/308 (25%), Positives = 114/308 (37%), Gaps = 21/308 (6%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V +++A ELP+ D+ G+ DPYV+V L K T+ K N Sbjct: 145 KLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLN 204 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP L Y Sbjct: 205 PVFNEQFTF---------------------------------KVPYSELGGKTLVMAVYD 231 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFPEAWHS--DAASIPGDGLASIRSKVYLTPKLWY 1081 + + H + GE + M T E W A + L I + P Sbjct: 232 FDRFSKHDIIGEFKVP--MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGK 289 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPG----RTLNPMWNEDLMFVAA 1249 L V ++EA++L D + YVK L R + TLNP +NE F Sbjct: 290 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV- 348 Query: 1250 EPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWYN 1393 PFE+ ++++V D GK+D IG+ + L H L N +QW+ Sbjct: 349 -PFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHT 407 Query: 1394 LEKHVMVD 1417 L+ VD Sbjct: 408 LQVEEEVD 415 Score = 43.1 bits (100), Expect = 0.007 Identities = 60/231 (25%), Positives = 99/231 (42%), Gaps = 12/231 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V +I+A +L D + YVK L + T+V +TLNP++NE F Sbjct: 159 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHR-KTLNPVFNEQFTFKV-- 215 Query: 1253 PFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 P+ E L+++V D K D+IG + + V D + +W +L+ Sbjct: 216 PYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV----DFGHVTEEWRDLQ-----SA 266 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 E+ ++ K IC +S PTA G L + IL A+ L Sbjct: 267 EKEEQEKLGD-----IC-------------FSLRYVPTA--------GKLTVVILEAKNL 300 Query: 1601 LPMKTKDGRGTTDPYC---VAKYGQKWVRTRTII--DSFTPKWNEQYTWEV 1738 K D G +DPY + + G++ + +T I ++ P +NE +++EV Sbjct: 301 ---KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV 348
>Q5RAG2:FA62A_PONPY Protein FAM62A - Pongo pygmaeus (Orangutan)| Length = 1104 Score = 62.4 bits (150), Expect = 1e-08 Identities = 117/538 (21%), Positives = 202/538 (37%), Gaps = 32/538 (5%) Frame = +2 Query: 605 VRVVKAKELPSKD------LTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSKER 766 + ++ A+ L SKD + G DPY V+LG +R +++ NP+W + + Sbjct: 333 IHLLAARGLTSKDKYVKGLIEGKSDPYALVRLGTQTFCSRVIDEELNPQWGETYEVMVHE 392 Query: 767 IQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGEL 946 + GR+ D+ +V + + + W+ L+ G + + L Sbjct: 393 VPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQ-----AGVLDDWFPLQ---GGQGQVHL 444 Query: 947 MLAVWMGTQADEAFPE---AWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLI 1117 L W+ +D E W+ +S P A+I L V + AQDL Sbjct: 445 RLE-WLSLLSDAEKLEQVLQWNQGVSSRPEPPSAAI------------LVVYLDRAQDLP 491 Query: 1118 PNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIA 1297 + P V+ + + ++ + T P+W E F +P + L + V Sbjct: 492 LKKGNKEPNPMVQLSIQDVTQESK-AVYSTNCPVWEEAFRFFLQDPQSQELDVQV----- 545 Query: 1298 PGKDDVIGRTVISLQHVARRL--DHKLLNSQWYNLEKHVMVDGEQRKETKFSSRI----H 1459 KDD T+ +L RL +L+ QW+ L R K RI Sbjct: 546 --KDDSRALTLGALTLPLARLLTAPELILDQWFQLSSS---GPNSRLYMKLVMRILYLDS 600 Query: 1460 LRICL------EGGYHVLDESTHYSSDL----RP--TAKQLWKHNIGVLELGILTAQGLL 1603 IC G + V E+ S + RP T VL + +L AQ L+ Sbjct: 601 SEICFPTVPGCPGAWDVDSENPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLI 660 Query: 1604 PMKTKDG---RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHD-PCTVITIGV 1771 G +G +DPY K + R+ + + P+WNE + V P + + V Sbjct: 661 AKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEVEV 720 Query: 1772 FDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLIVLTPAGVKKMGEVQLAV 1951 FD + +D +G+ ++ L+T+ + + + + P+G + +L Sbjct: 721 FDK---------DLDKDDFLGRCKVSLTTV-LNSGFLDEWLTLEDVPSGRLHLRLERLTP 770 Query: 1952 RFTCSSLLNMMTLYSQPLLPKMHYVHPLSVIQVDNLRRQATNIVSTRLSRAEP-PLRK 2122 R T + L ++ + S+IQ A ++S + RAE PLRK Sbjct: 771 RPTAAELEEVLQVN--------------SLIQTQKSAELAAALLSIYMERAEDLPLRK 814 Score = 55.8 bits (133), Expect = 1e-06 Identities = 94/420 (22%), Positives = 162/420 (38%), Gaps = 35/420 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSKERIQAS 778 L V + +A++LP K +P V++ + + ++ P W + F F + Q+ Sbjct: 480 LVVYLDRAQDLPLKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFRFFLQDPQSQ 539 Query: 779 XXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGH-KVKGELMLA 955 G + L + + + QW++L + ++ +L++ Sbjct: 540 ELDVQVKDDSRALTL--GALTLPLARL---LTAPELILDQWFQLSSSGPNSRLYMKLVMR 594 Query: 956 VWMGTQADEAFPE------AWHSDAASIP-GDGLASIRSKVYLTPKLWY-----LRVNVI 1099 + ++ FP AW D+ + G + + + TP + LR++V+ Sbjct: 595 ILYLDSSEICFPTVPGCPGAWDVDSENPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVL 654 Query: 1100 EAQDLIPNDK------TRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFE 1261 EAQDLI D+ + YVK L ++ R+ V LNP WNE + Sbjct: 655 EAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVR-EDLNPRWNEVFEVIVTSVPG 713 Query: 1262 EHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQRKETK 1441 + L + V D+ KDD +GR +SL V L+ L+ +W LE Sbjct: 714 QELEVEVFDKDLD-KDDFLGRCKVSLTTV---LNSGFLD-EWLTLEDVP----------- 757 Query: 1442 FSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILT--------AQG 1597 S R+HLR L+ T RPTA +L + VL++ L A Sbjct: 758 -SGRLHLR---------LERLTP-----RPTAAELEE----VLQVNSLIQTQKSAELAAA 798 Query: 1598 LLP--------MKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDPCT 1753 LL + + G PY G +T+T+ + P W+E ++ + P T Sbjct: 799 LLSIYMERAEDLPLRKGTKHPSPYATLTVGDTSHKTKTVSQTSAPVWDESASFLIRKPHT 858 Score = 52.4 bits (124), Expect = 1e-05 Identities = 88/422 (20%), Positives = 153/422 (36%), Gaps = 42/422 (9%) Frame = +2 Query: 599 LYVRVVKAKELPSKD------LTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSK 760 L + V++A++L +KD + G DPYV++KL + + NP WN+VF Sbjct: 649 LRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIV 708 Query: 761 ERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKG 940 + GR L V +S +W LE+ ++ Sbjct: 709 TSVPGQELEVEVFDKDLDKDDFLGRCKVSLTTVL-----NSGFLDEWLTLEDVPSGRLHL 763 Query: 941 ELMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIP 1120 L T A+ +S + LA+ +Y+ A+DL Sbjct: 764 RLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSIYME-----------RAEDLPL 812 Query: 1121 NDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAP 1300 T+ P Y +G+ + +T+ + +T P+W+E F+ +P E+L L V Sbjct: 813 RKGTKHPSPYATLTVGDTSHKTK-TVSQTSAPVWDESASFLIRKPHTENLELQVRGE--- 868 Query: 1301 GKDDVIGRTVISLQHVARRLDHKLLNSQWYNLE-----------------KHVMVDGEQR 1429 V+G + L + + +L +W+ L +H V+ Sbjct: 869 -GTGVLGSLSLPLSELL--VADQLCLDRWFTLNSGQGQVLLRAQLGILVSQHSGVEAHSH 925 Query: 1430 KETKFSSRIHLRICLEGGY-HVLDES-------THYSSDLRPTAKQLWKHNIGVLELG-- 1579 + SS + L GG HV + TH S L A L + + V Sbjct: 926 SYSHSSSSLSEEPELSGGPPHVTSSAPELRQRLTHVDSSLEAPAGPLGQVKLTVWYYSEE 985 Query: 1580 ---ILTAQGLLPMKTKDGRGTTDPYCVA------KYGQKWVRTRTIIDSFTPKWNEQYTW 1732 + G ++ ++GR DPY G K +T + +P++NE++ W Sbjct: 986 RKLVSIVHGCRALR-QNGRDPPDPYVSLLLLPDKNRGTKR-KTSQKKRTLSPEFNERFEW 1043 Query: 1733 EV 1738 E+ Sbjct: 1044 EL 1045 Score = 40.8 bits (94), Expect = 0.035 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 4/76 (5%) Frame = +2 Query: 1562 GVLELGILTAQGLLPM-KTKDG--RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTW 1732 G++ + +L A+GL K G G +DPY + + G + +R I + P+W E Y Sbjct: 329 GIIRIHLLAARGLTSKDKYVKGLIEGKSDPYALVRLGTQTFCSRVIDEELNPQWGETYEV 388 Query: 1733 EVHD-PCTVITIGVFD 1777 VH+ P I + VFD Sbjct: 389 MVHEVPGQEIEVEVFD 404
>P34693:SYT1_CAEEL Synaptotagmin-1 - Caenorhabditis elegans| Length = 441 Score = 62.0 bits (149), Expect = 1e-08 Identities = 81/309 (26%), Positives = 130/309 (42%), Gaps = 24/309 (7%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFS 757 Q L V V++A++LP D++G+ DPYV++ L K T+ K NP +N+ F F Sbjct: 172 QQGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIF- 230 Query: 758 KERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVK 937 +V F NE+ + L Y + + H Sbjct: 231 -------------------------KVAF--NEITAKT-----LVFAIYDFDRFSKHDQI 258 Query: 938 GELMLAVWMGTQADEAFPEAWHSDAASIPGD-----GLASIRSKVYLTPKLWYLRVNVIE 1102 G++++ +G A E W D A P D L I + P L V ++E Sbjct: 259 GQVLIP--LGKIDLGAVIEEW-KDIAPPPDDKEAEKSLGDICFSLRYVPTAGKLTVVILE 315 Query: 1103 AQDLIPNDKTRFPEVYVKAML--GNQALRTRVSPGR--TLNPMWNEDLMFVAAEPFEE-- 1264 A++L D + YVK +L G + L+ + + + TLNP +NE F PFE+ Sbjct: 316 AKNLKKMDVGGLSDPYVKIVLMQGGKRLKKKKTSIKKCTLNPYYNESFSFEV--PFEQIQ 373 Query: 1265 --HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH--KLLNS------QWYNLEKHVMV 1414 L+++V D G +D IGR ++ L H +L S QW+ L V Sbjct: 374 KVSLMITVMDYDKLGSNDAIGRCLLGCNGTGAELRHWMDMLASPRRPIAQWHTLGP-VEE 432 Query: 1415 DGEQRKETK 1441 +G+++ + K Sbjct: 433 EGDKKDDKK 441
>P24505:SY61_DISOM Synaptotagmin A - Discopyge ommata (Electric ray)| Length = 427 Score = 62.0 bits (149), Expect = 1e-08 Identities = 78/308 (25%), Positives = 115/308 (37%), Gaps = 21/308 (6%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V +++A ELP+ D+ G+ DPYV+V + K T+ K N Sbjct: 150 KLQFSLDYDFQNNQLIVGIIQAAELPALDVGGTSDPYVKVFVLPDKKKKYETKVHRKTLN 209 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F ++P L Y Sbjct: 210 PVFNESFIF---------------------------------KIPYSELGGKTLVMAVYD 236 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFPEAWHS--DAASIPGDGLASIRSKVYLTPKLWY 1081 + + H V GE + M T E W A + L I + P Sbjct: 237 FDRFSKHDVIGEAKVP--MNTVDFGHVTEEWRDLQGAEKEEQEKLGDICFSLRYVPTAGK 294 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPG----RTLNPMWNEDLMFVAA 1249 L V ++EA++L D + YVK L R + TLNP +NE F Sbjct: 295 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV- 353 Query: 1250 EPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWYN 1393 PFE+ ++++V D GK+D IG+ + A L H L N +QW+ Sbjct: 354 -PFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTAAELRHWSDMLANPRRPIAQWHT 412 Query: 1394 LEKHVMVD 1417 L+ VD Sbjct: 413 LQPEEEVD 420 Score = 42.0 bits (97), Expect = 0.015 Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 12/231 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V +I+A +L D + YVK + + T+V +TLNP++NE +F Sbjct: 164 LIVGIIQAAELPALDVGGTSDPYVKVFVLPDKKKKYETKVHR-KTLNPVFNESFIFKI-- 220 Query: 1253 PFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 P+ E L+++V D K DVIG + + V D + +W +L+ Sbjct: 221 PYSELGGKTLVMAVYDFDRFSKHDVIGEAKVPMNTV----DFGHVTEEWRDLQ-----GA 271 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 E+ ++ K IC +S PTA G L + IL A+ L Sbjct: 272 EKEEQEKLGD-----IC-------------FSLRYVPTA--------GKLTVVILEAKNL 305 Query: 1601 LPMKTKDGRGTTDPYC---VAKYGQKWVRTRTII--DSFTPKWNEQYTWEV 1738 K D G +DPY + + G++ + +T I ++ P +NE +++EV Sbjct: 306 ---KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV 353
>P24507:SY63_DISOM Synaptotagmin C - Discopyge ommata (Electric ray)| Length = 537 Score = 61.6 bits (148), Expect = 2e-08 Identities = 68/254 (26%), Positives = 106/254 (41%), Gaps = 11/254 (4%) Frame = +2 Query: 593 QYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFSKE 763 + L V+++KA +LP+KD G DPYV++ L K T+ K NP +N+ F F+ Sbjct: 251 EQLVVKILKALDLPAKDANGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFN-- 308 Query: 764 RIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGE 943 NE+ R L Y + + H + G+ Sbjct: 309 --------------------------VPFNELQNR-----KLHFSVYDFDRFSRHDLIGQ 337 Query: 944 LMLAVWMGTQADEAFPEAWHS--DAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLI 1117 ++L + W +A S D L I + P L + +I+A +L Sbjct: 338 VVLDNLLEFSDFSEDTTIWRDILEATSEKAD-LGEINFSLCYLPTAGRLTITIIKATNLK 396 Query: 1118 PNDKTRFPEVYVKAML--GNQALRTRVS--PGRTLNPMWNEDLMFVAAEPFEEH--LILS 1279 D T F + YVKA L + L+ R + TLNP++NE L+F EH +I++ Sbjct: 397 AMDLTGFSDPYVKASLICDERRLKKRKTSIKKNTLNPVYNEALVFDIPNENMEHVNVIIA 456 Query: 1280 VEDRIAPGKDDVIG 1321 V D G ++VIG Sbjct: 457 VMDYDCIGHNEVIG 470 Score = 35.8 bits (81), Expect = 1.1 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 7/91 (7%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V +++A DL D F + YVK L + +T+V +TLNP++NE F Sbjct: 253 LVVKILKALDLPAKDANGFSDPYVKIYLLPDRKKKFQTKVHR-KTLNPIFNETFQFNV-- 309 Query: 1253 PFEE----HLILSVEDRIAPGKDDVIGRTVI 1333 PF E L SV D + D+IG+ V+ Sbjct: 310 PFNELQNRKLHFSVYDFDRFSRHDLIGQVVL 340
>O43374:RASL2_HUMAN Ras GTPase-activating protein 4 - Homo sapiens (Human)| Length = 803 Score = 61.6 bits (148), Expect = 2e-08 Identities = 59/256 (23%), Positives = 104/256 (40%), Gaps = 6/256 (2%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSKERIQAS 778 LY+R+V+ K LP+KD+TGS DPY VK+ N +T W + F E Q Sbjct: 7 LYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPII------RTATVWKTLCPFWGEEYQV- 59 Query: 779 XXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGELMLAV 958 +PP A +Y ++E + +++ V Sbjct: 60 -----------------------------HLPPTFH-AVAFYVMDE--DALSRDDVIGKV 87 Query: 959 WMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLW------YLRVNVIEAQDLIP 1120 + + P+ + A D ++ +++L ++W LR +V+EA+DL P Sbjct: 88 CLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAP 147 Query: 1121 NDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAP 1300 D+ + +V+ + T + ++ P WNE F E E L + D Sbjct: 148 KDRNGTSDPFVRVRYKGRTRETSIVK-KSCYPRWNETFEFELQEGAMEALCVEAWDWDLV 206 Query: 1301 GKDDVIGRTVISLQHV 1348 ++D +G+ VI +Q + Sbjct: 207 SRNDFLGKVVIDVQRL 222 Score = 59.7 bits (143), Expect = 7e-08 Identities = 76/316 (24%), Positives = 128/316 (40%), Gaps = 7/316 (2%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFE 1261 L + ++E ++L D T + Y + N+ + + +TL P W E+ V P Sbjct: 7 LYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQ-VHLPPTF 65 Query: 1262 EHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQRKETK 1441 + V D A +DDVIG+ ++ +A H S W +L + VD ++ + Sbjct: 66 HAVAFYVMDEDALSRDDVIGKVCLTRDTIA---SHPKGFSGWAHLTE---VDPDE----E 115 Query: 1442 FSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGLLPMKTKD 1621 IHLR+ ++ P A+ L +L A+ L P KD Sbjct: 116 VQGEIHLRL-----------------EVWPGARAC------RLRCSVLEARDLAP---KD 149 Query: 1622 GRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDPCTVITIGVFDNCHLNGGE 1801 GT+DP+ +Y + T + S P+WNE + +E+ + G + + + Sbjct: 150 RNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQE-------GAMEALCVEAWD 202 Query: 1802 KANGARDTRIGKVRIRLSTLETDRVYTHSYPLIVLTPAGVK-------KMGEVQLAVRFT 1960 +R+ +GKV I + L RV L P K +G +QL VR Sbjct: 203 WDLVSRNDFLGKVVIDVQRL---RVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLR 259 Query: 1961 CSSLLNMMTLYSQPLL 2008 ++L + Y QPL+ Sbjct: 260 DETVL--PSSYYQPLV 273
>P46097:SYT2_MOUSE Synaptotagmin-2 - Mus musculus (Mouse)| Length = 422 Score = 60.8 bits (146), Expect = 3e-08 Identities = 77/309 (24%), Positives = 119/309 (38%), Gaps = 22/309 (7%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V V++A ELP+ D+ G+ DPYV+V L K T+ K N Sbjct: 145 KLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLN 204 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP + L Y Sbjct: 205 PAFNETFTF---------------------------------KVPYQELAGKTLVMAIYD 231 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFP-EAWH--SDAASIPGDGLASIRSKVYLTPKLW 1078 + + H + GE+ + + D P E W + L I + + P Sbjct: 232 FDRFSKHDIIGEVKVPM---NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAG 288 Query: 1079 YLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTR----VSPGRTLNPMWNEDLMFVA 1246 L V ++EA++L D + YVK L R + +TLNP +NE F Sbjct: 289 KLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEI 348 Query: 1247 AEPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWY 1390 PFE+ ++++V D GK++ IG+ + L H L N +QW+ Sbjct: 349 --PFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWH 406 Query: 1391 NLEKHVMVD 1417 +L+ VD Sbjct: 407 SLKPEEEVD 415
>P29101:SYT2_RAT Synaptotagmin-2 - Rattus norvegicus (Rat)| Length = 422 Score = 60.5 bits (145), Expect = 4e-08 Identities = 77/309 (24%), Positives = 119/309 (38%), Gaps = 22/309 (7%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V V++A ELP+ D+ G+ DPYV+V L K T+ K N Sbjct: 145 KLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLN 204 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP + L Y Sbjct: 205 PAFNETFTF---------------------------------KVPYQELGGKTLVMAIYD 231 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFP-EAWH--SDAASIPGDGLASIRSKVYLTPKLW 1078 + + H + GE+ + + D P E W + L I + + P Sbjct: 232 FDRFSKHDIIGEVKVPM---NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAG 288 Query: 1079 YLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTR----VSPGRTLNPMWNEDLMFVA 1246 L V ++EA++L D + YVK L R + +TLNP +NE F Sbjct: 289 KLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEI 348 Query: 1247 AEPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWY 1390 PFE+ ++++V D GK++ IG+ + L H L N +QW+ Sbjct: 349 --PFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWH 406 Query: 1391 NLEKHVMVD 1417 +L+ VD Sbjct: 407 SLKPEEEVD 415
>Q8N9I0:SYT2_HUMAN Synaptotagmin-2 - Homo sapiens (Human)| Length = 419 Score = 60.5 bits (145), Expect = 4e-08 Identities = 77/309 (24%), Positives = 119/309 (38%), Gaps = 22/309 (7%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V V++A ELP+ D+ G+ DPYV+V L K T+ K N Sbjct: 142 KLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLN 201 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP + L Y Sbjct: 202 PAFNETFTF---------------------------------KVPYQELGGKTLVMAIYD 228 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFP-EAWH--SDAASIPGDGLASIRSKVYLTPKLW 1078 + + H + GE+ + + D P E W + L I + + P Sbjct: 229 FDRFSKHDIIGEVKVPM---NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAG 285 Query: 1079 YLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTR----VSPGRTLNPMWNEDLMFVA 1246 L V ++EA++L D + YVK L R + +TLNP +NE F Sbjct: 286 KLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEI 345 Query: 1247 AEPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWY 1390 PFE+ ++++V D GK++ IG+ + L H L N +QW+ Sbjct: 346 --PFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWH 403 Query: 1391 NLEKHVMVD 1417 +L+ VD Sbjct: 404 SLKPEEEVD 412
>P24506:SY62_DISOM Synaptotagmin B - Discopyge ommata (Electric ray)| Length = 439 Score = 60.1 bits (144), Expect = 5e-08 Identities = 79/311 (25%), Positives = 120/311 (38%), Gaps = 24/311 (7%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 K+ + D Q L V +++A ELP+ D+ G+ DPYV+V L K T+ +K N Sbjct: 162 KIQFSLDYDFQANQLTVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVQKKTLN 221 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP + L Y Sbjct: 222 PTFNESFVF---------------------------------KVPYQELGGKTLMMAVYD 248 Query: 908 LEERNGHKVKGE---LMLAVWMGTQADEAFPEAWH--SDAASIPGDGLASIRSKVYLTPK 1072 + + H G+ LM V +G Q +E W A + L I + + P Sbjct: 249 FDRFSKHDCIGQVTVLMTKVDLGQQLEE-----WRDLESAEKEEPEKLGDICTSLRYVPT 303 Query: 1073 LWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTR----VSPGRTLNPMWNEDLMF 1240 L V ++EA++L D + YVK L R + TLNP +NE F Sbjct: 304 AGKLTVCILEAKNLKKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTLNPYYNESFSF 363 Query: 1241 VAAEPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQ 1384 PFE+ + ++V D GK+D IG+ + L H L N +Q Sbjct: 364 EI--PFEQIQKVQVCVTVLDYDKIGKNDAIGKIFVGSNASGTELRHWSDMLANPRRPIAQ 421 Query: 1385 WYNLEKHVMVD 1417 W++L+ VD Sbjct: 422 WHSLKPEEEVD 432 Score = 40.0 bits (92), Expect = 0.059 Identities = 61/231 (26%), Positives = 99/231 (42%), Gaps = 12/231 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V +I+A +L D + YVK L + T+V +TLNP +NE FV Sbjct: 176 LTVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVQK-KTLNPTFNES--FVFKV 232 Query: 1253 PFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 P++E L+++V D K D IG+ + + V L +L +W +LE Sbjct: 233 PYQELGGKTLMMAVYDFDRFSKHDCIGQVTVLMTKV--DLGQQL--EEWRDLE-----SA 283 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 E+ + K IC Y PTA G L + IL A+ L Sbjct: 284 EKEEPEKLGD-----ICTSLRY-------------VPTA--------GKLTVCILEAKNL 317 Query: 1601 LPMKTKDGRGTTDPYC---VAKYGQKWVRTRTII--DSFTPKWNEQYTWEV 1738 K D G +DPY + + G++ + +T + ++ P +NE +++E+ Sbjct: 318 ---KKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEI 365
>Q62746:SYT6_RAT Synaptotagmin-6 - Rattus norvegicus (Rat)| Length = 511 Score = 57.0 bits (136), Expect = 5e-07 Identities = 69/272 (25%), Positives = 112/272 (41%), Gaps = 12/272 (4%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFS 757 + + L VR++KA +LP+KD GS DPYV++ L K TR K NP +++ F F Sbjct: 243 ESETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHF- 301 Query: 758 KERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVK 937 VP D L + + + H + Sbjct: 302 --------------------------------PVPYEELADRKLHLSVFDFDRFSRHDMI 329 Query: 938 GELMLAVWMGTQADEAFPEAWHS-DAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDL 1114 GE++L W A+ L I + P L + VI+ ++L Sbjct: 330 GEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNL 389 Query: 1115 IPNDKTRFPEVYVKAML---GNQALRTRVS-PGRTLNPMWNEDLMF-VAAEPFEE-HLIL 1276 D T + + YVK L G + + + + TLNP++NE ++F + E ++ L++ Sbjct: 390 KAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLI 449 Query: 1277 SVEDRIAPGKDDVIG--RTVISLQHVARRLDH 1366 SV D G +++IG R IS + + R DH Sbjct: 450 SVMDYDRVGHNEIIGVCRVGISAEGLGR--DH 479
>P41823:SY65_APLCA Synaptotagmin-1 - Aplysia californica (California sea hare)| Length = 428 Score = 57.0 bits (136), Expect = 5e-07 Identities = 77/304 (25%), Positives = 121/304 (39%), Gaps = 22/304 (7%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL + D Q L V V++A +LP D++G+ DPYV+V L K T+ K N Sbjct: 156 KLQFSLDYDFQKGELSVNVIQAADLPGMDMSGTSDPYVKVYLLPDKKKKYETKVHRKTLN 215 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +N+ F F +VP L Y Sbjct: 216 PVFNESFTF---------------------------------KVPYAEVGSKILTFAVYD 242 Query: 908 LEERNGHKVKGELML---AVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLW 1078 + + H G++ + ++ +G + E + + D S + L I + P Sbjct: 243 FDRFSKHDQIGQVQVPLNSIDLG-RVVEDWKDLQSPDTESEKENKLGDICFSLRYVPTAG 301 Query: 1079 YLRVNVIEAQDLIPNDKTRFPEVYVKAML--GNQALRTRVS--PGRTLNPMWNEDLMFVA 1246 L V ++EA++L D + YVK L G + L+ + + TLNP +NE F Sbjct: 302 KLTVVILEAKNLKKMDVGGLSDPYVKIALLQGTKRLKKKKTTIKKNTLNPYFNESFGFEV 361 Query: 1247 AEPFEE----HLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH---KLLN-----SQWY 1390 PFE+ LI++V D G + IGR V+ L H L N +QW+ Sbjct: 362 --PFEQIQKVTLIITVVDYDRIGTSEPIGRCVLGCNSSGTELRHWSDMLANPRRPIAQWH 419 Query: 1391 NLEK 1402 L++ Sbjct: 420 TLQE 423 Score = 44.7 bits (104), Expect = 0.002 Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 10/229 (4%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGRTLNPMWNEDLMFVA-- 1246 L VNVI+A DL D + + YVK L + T+V +TLNP++NE F Sbjct: 170 LSVNVIQAADLPGMDMSGTSDPYVKVYLLPDKKKKYETKVH-RKTLNPVFNESFTFKVPY 228 Query: 1247 AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQ 1426 AE + L +V D K D IG+ + L + D + W +L+ D E Sbjct: 229 AEVGSKILTFAVYDFDRFSKHDQIGQVQVPLNSI----DLGRVVEDWKDLQS---PDTES 281 Query: 1427 RKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGLLP 1606 KE K IC +S PTA G L + IL A+ L Sbjct: 282 EKENKLGD-----IC-------------FSLRYVPTA--------GKLTVVILEAKNL-- 313 Query: 1607 MKTKDGRGTTDPY---CVAKYGQKWVRTRTII--DSFTPKWNEQYTWEV 1738 K D G +DPY + + ++ + +T I ++ P +NE + +EV Sbjct: 314 -KKMDVGGLSDPYVKIALLQGTKRLKKKKTTIKKNTLNPYFNESFGFEV 361
>Q6DN12:MCTP2_HUMAN Multiple C2 and transmembrane domain-containing protein 2 - Homo| sapiens (Human) Length = 878 Score = 57.0 bits (136), Expect = 5e-07 Identities = 68/312 (21%), Positives = 126/312 (40%), Gaps = 13/312 (4%) Frame = +2 Query: 1001 HSDAASIPG---DGLASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGN 1171 H + S+PG DGL+++ S P + L +++ E ++L+ D+ + YVK L Sbjct: 171 HFEEQSVPGEASDGLSNLPS-----PFAYLLTIHLKEGRNLVVRDRCGTSDPYVKFKLNG 225 Query: 1172 QALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVI------ 1333 + L + LNP+W+E ++ + + ++ L + V DR D + VI Sbjct: 226 KTLYKSKVIYKNLNPVWDE-IVVLPIQSLDQKLRVKVYDRDLTTSDFMGSAFVILSDLEL 284 Query: 1334 --SLQHVARRLDHKLLNSQW--YNLEKHVMVDGEQRKETKFSSRIHLRICLEGGYHVLDE 1501 + +H+ + D L L +++V K ++S+R L L Sbjct: 285 NRTTEHILKLEDPNSLEDDMGVIVLNLNLVVKQGDFKRHRWSNRKR----LSASKSSLIR 340 Query: 1502 STHYSSDLRPTAKQLWKHNIGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRT 1681 + S L+ QLW I + LL K G T+ + K G + ++ Sbjct: 341 NLRLSESLK--KNQLWNGIISIT---------LLEGKNVSGGSMTEMFVQLKLGDQRYKS 389 Query: 1682 RTIIDSFTPKWNEQYTWEVHDPCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTL 1861 +T+ S P+W E + + +G+ D + K N + R+G ++ +S L Sbjct: 390 KTLCKSANPQWQEHFDFHYFSD----RMGILD---IEVWGKDNKKHEERLGTCKVDISAL 442 Query: 1862 ETDRVYTHSYPL 1897 + PL Sbjct: 443 PLKQANCLELPL 454 Score = 52.0 bits (123), Expect = 1e-05 Identities = 23/74 (31%), Positives = 44/74 (59%) Frame = +2 Query: 1556 NIGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWE 1735 ++G+L++ +L A LL D G +DP+C+ + G ++T T+ + P+WN+ +T+ Sbjct: 507 DVGILQVKVLKAADLL---AADFSGKSDPFCLLELGNDRLQTHTVYKNLNPEWNKVFTFP 563 Query: 1736 VHDPCTVITIGVFD 1777 + D V+ + VFD Sbjct: 564 IKDIHDVLEVTVFD 577 Score = 50.8 bits (120), Expect = 3e-05 Identities = 24/58 (41%), Positives = 36/58 (62%) Frame = +2 Query: 581 VEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF 754 V+ + L V+V+KA +L + D +G DP+ ++LGN + T K NPEWN+VF F Sbjct: 505 VKDVGILQVKVLKAADLLAADFSGKSDPFCLLELGNDRLQTHTVYKNLNPEWNKVFTF 562 Score = 42.4 bits (98), Expect = 0.012 Identities = 21/84 (25%), Positives = 43/84 (51%) Frame = +1 Query: 2452 DEEFDTFPTSRPPDIVRMRYDRLRSVAGRIQTVVGDLATQGERLQSLLSWRDPRATALFV 2631 DEE + S ++ Y ++ + +Q V+ ++A+ GER+++ +W P ++L Sbjct: 743 DEEDEDDKESEKKGLIERIY-MVQDIVSTVQNVLEEIASFGERIKNTFNWTVPFLSSLAC 801 Query: 2632 TFCFIAAIVLYVTPFRVVVFLAGL 2703 A I+LY P R ++ + G+ Sbjct: 802 LILAAATIILYFIPLRYIILIWGI 825 Score = 35.8 bits (81), Expect = 1.1 Identities = 57/269 (21%), Positives = 106/269 (39%), Gaps = 22/269 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSC--DPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFS--KER 766 L+ ++ L K+++G + +V++KLG+ + ++ K NP+W + F F +R Sbjct: 353 LWNGIISITLLEGKNVSGGSMTEMFVQLKLGDQRYKSKTLCKSANPQWQEHFDFHYFSDR 412 Query: 767 IQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKR------VPPDSPLAPQWYRLEERNGH 928 + G D++ +P + +P DS L Sbjct: 413 M-GILDIEVWGKDNKKHEERLGTCKVDISALPLKQANCLELPLDSCL------------- 458 Query: 929 KVKGELMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPK------------ 1072 G L++ V + A + SD P LA + + +T + Sbjct: 459 ---GALLMLVTLTPCAGVSV-----SDLCVCP---LADLSERKQITQRYCLQNSLKDVKD 507 Query: 1073 LWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 + L+V V++A DL+ D + + + LGN L+T + + LNP WN+ F + Sbjct: 508 VGILQVKVLKAADLLAADFSGKSDPFCLLELGNDRLQTH-TVYKNLNPEWNKVFTF-PIK 565 Query: 1253 PFEEHLILSVEDRIAPGKDDVIGRTVISL 1339 + L ++V D D +G+ I L Sbjct: 566 DIHDVLEVTVFDEDGDKPPDFLGKVAIPL 594
>P27715:UNC13_CAEEL Phorbol ester/diacylglycerol-binding protein unc-13 - Caenorhabditis| elegans Length = 2155 Score = 56.6 bits (135), Expect = 6e-07 Identities = 46/176 (26%), Positives = 79/176 (44%), Gaps = 17/176 (9%) Frame = +2 Query: 1016 SIPGDGLASIRSKVYLTPKLWYLRVN--VIEAQDLIPNDKTRFPEVYVKAMLGNQALRTR 1189 +I + L ++++ + W ++ V+ AQ LI DKT + YV A +G RTR Sbjct: 1135 NIQKETLKTVKASILEGSSKWSAKITLTVLCAQGLIAKDKTGKSDPYVTAQVGKTKRRTR 1194 Query: 1190 VSPGRTLNPMWNEDLMF----------VAAEPFEEHLILSVEDRIAPGKDDVIGRTVISL 1339 + + LNP+WNE F V + L + ++ DD +G+TVI + Sbjct: 1195 -TIHQELNPVWNEKFHFECHNSTDRIKVRVWDEDNDLKSKLRQKLTRESDDFLGQTVIEV 1253 Query: 1340 QHVARRLDHKLLNSQWYNLEKHVMVDGEQRKETKFSSRIHLRICLEG-----GYHV 1492 + ++ +D WYNLEK + + R+H+ + ++G YHV Sbjct: 1254 RTLSGEMD------VWYNLEKRT-----DKSAVSGAIRLHINVEIKGEEKLAPYHV 1298 Score = 53.1 bits (126), Expect = 7e-06 Identities = 28/70 (40%), Positives = 40/70 (57%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDP 1747 + L +L AQGL+ KD G +DPY A+ G+ RTRTI P WNE++ +E H+ Sbjct: 1159 ITLTVLCAQGLI---AKDKTGKSDPYVTAQVGKTKRRTRTIHQELNPVWNEKFHFECHNS 1215 Query: 1748 CTVITIGVFD 1777 I + V+D Sbjct: 1216 TDRIKVRVWD 1225 Score = 45.4 bits (106), Expect = 0.001 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 6/101 (5%) Frame = +2 Query: 470 FKMMQRPFRPEEYSLKETTPHL------GGAAAGDKLTTTYDLVEQMQYLYVRVVKAKEL 631 F+M++ F +E KET + G + K+T T V+ A+ L Sbjct: 1123 FQMIRTVFDVDENIQKETLKTVKASILEGSSKWSAKITLT-------------VLCAQGL 1169 Query: 632 PSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF 754 +KD TG DPYV ++G K TR ++ NP WN+ F F Sbjct: 1170 IAKDKTGKSDPYVTAQVGKTKRRTRTIHQELNPVWNEKFHF 1210
>Q9R0N8:SYT6_MOUSE Synaptotagmin-6 - Mus musculus (Mouse)| Length = 511 Score = 56.6 bits (135), Expect = 6e-07 Identities = 65/270 (24%), Positives = 108/270 (40%), Gaps = 10/270 (3%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFS 757 + + L VR++KA +LP+KD GS DPYV++ L K TR K NP +++ F F Sbjct: 243 ESETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHF- 301 Query: 758 KERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVK 937 VP D L + + + H + Sbjct: 302 --------------------------------PVPYEELADRKLHLSVFDFDRFSRHDMI 329 Query: 938 GELMLAVWMGTQADEAFPEAWHS-DAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDL 1114 GE++L W A+ L I + P L + VI+ ++L Sbjct: 330 GEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNL 389 Query: 1115 IPNDKTRFPEVYVKAML---GNQALRTRVS-PGRTLNPMWNEDLMF-VAAEPFEE-HLIL 1276 D T + + YVK L G + + + + TLNP++NE ++F + E ++ L++ Sbjct: 390 KAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLI 449 Query: 1277 SVEDRIAPGKDDVIGRTVISLQHVARRLDH 1366 SV D G +++IG + + DH Sbjct: 450 SVMDYDRVGHNEIIGVCRVGINAEGLGRDH 479
>Q86SS6:SYT9_HUMAN Synaptotagmin-9 - Homo sapiens (Human)| Length = 491 Score = 56.2 bits (134), Expect = 8e-07 Identities = 80/310 (25%), Positives = 129/310 (41%), Gaps = 19/310 (6%) Frame = +2 Query: 494 RPEEY---SLKETTPHLGGAAAGDKLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDP 664 +PE Y SL + A KL ++ L V++ KA LP+KD +G+ DP Sbjct: 199 KPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDP 258 Query: 665 YVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGR 835 YV++ L K T+ K NP +++VF F Sbjct: 259 YVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLF--------------------------- 291 Query: 836 VMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGELMLAVWMGTQADEAFPE---AWHS 1006 VP L Y + + H + G++++ ++ AD FP W Sbjct: 292 ------PVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDL-AD--FPRECILW-K 341 Query: 1007 DAASIPGDG--LASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAML---GN 1171 D + D L + + P L + +I+A++L D T + YVK L G Sbjct: 342 DIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGR 401 Query: 1172 QALRTRVSPGR-TLNPMWNEDLMF-VAAEPFEE-HLILSVEDRIAPGKDDVIGRTVISLQ 1342 + + + S R TLNP++NE ++F V E ++ HL ++V D G +++IG V + Sbjct: 402 RLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIG--VCQVG 459 Query: 1343 HVARRL--DH 1366 + A RL DH Sbjct: 460 NEAERLGRDH 469
>Q5T7P8:SYT6_HUMAN Synaptotagmin-6 - Homo sapiens (Human)| Length = 510 Score = 56.2 bits (134), Expect = 8e-07 Identities = 65/270 (24%), Positives = 108/270 (40%), Gaps = 10/270 (3%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFS 757 + + L VR++KA +LP+KD GS DPYV++ L K TR K NP +++ F F Sbjct: 242 ETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHF- 300 Query: 758 KERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVK 937 VP D L + + + H + Sbjct: 301 --------------------------------PVPYEELADRKLHLSVFDFDRFSRHDMI 328 Query: 938 GELMLAVWMGTQADEAFPEAWHS-DAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDL 1114 GE++L W A+ L I + P L + VI+ ++L Sbjct: 329 GEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNL 388 Query: 1115 IPNDKTRFPEVYVKAML---GNQALRTRVS-PGRTLNPMWNEDLMF-VAAEPFEE-HLIL 1276 D T + + YVK L G + + + + TLNP++NE ++F + E ++ L++ Sbjct: 389 KAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLI 448 Query: 1277 SVEDRIAPGKDDVIGRTVISLQHVARRLDH 1366 SV D G +++IG + + DH Sbjct: 449 SVMDYDRVGHNEIIGVCRVGITAEGLGRDH 478
>Q925C0:SYT9_RAT Synaptotagmin-9 - Rattus norvegicus (Rat)| Length = 491 Score = 55.8 bits (133), Expect = 1e-06 Identities = 81/310 (26%), Positives = 130/310 (41%), Gaps = 19/310 (6%) Frame = +2 Query: 494 RPEEY---SLKETTPHLGGAAAGDKLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDP 664 +PE Y SL + A KL ++ L V++ KA LP+KD +G+ DP Sbjct: 199 KPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDP 258 Query: 665 YVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGR 835 YV++ L K T+ K NP +++VF F Sbjct: 259 YVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFP-------------------------- 292 Query: 836 VMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGELMLAVWMGTQADEAFPE---AWHS 1006 N++ R L Y + + H + G++++ + AD FP W Sbjct: 293 --VHYNDLEAR-----KLHFSVYDFDRFSRHDLIGQVVVDHFFDL-AD--FPRECILW-K 341 Query: 1007 DAASIPGDG--LASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAML---GN 1171 D + D L + + P L + +I+A++L D T + YVK L G Sbjct: 342 DIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGR 401 Query: 1172 QALRTRVSPGR-TLNPMWNEDLMF-VAAEPFEE-HLILSVEDRIAPGKDDVIGRTVISLQ 1342 + + + S R TLNP++NE ++F V E ++ HL ++V D G ++VIG V + Sbjct: 402 RLKKRKTSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVMDYDRVGHNEVIG--VCQVG 459 Query: 1343 HVARRL--DH 1366 + A RL DH Sbjct: 460 NEAERLGRDH 469
>Q9R0N9:SYT9_MOUSE Synaptotagmin-9 - Mus musculus (Mouse)| Length = 491 Score = 55.8 bits (133), Expect = 1e-06 Identities = 81/310 (26%), Positives = 130/310 (41%), Gaps = 19/310 (6%) Frame = +2 Query: 494 RPEEY---SLKETTPHLGGAAAGDKLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDP 664 +PE Y SL + A KL ++ L V++ KA LP+KD +G+ DP Sbjct: 199 KPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDP 258 Query: 665 YVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGR 835 YV++ L K T+ K NP +++VF F Sbjct: 259 YVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFP-------------------------- 292 Query: 836 VMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGELMLAVWMGTQADEAFPE---AWHS 1006 N++ R L Y + + H + G++++ + AD FP W Sbjct: 293 --VHYNDLEAR-----KLHFSVYDFDRFSRHDLIGQVVVDHFFDL-AD--FPRECILW-K 341 Query: 1007 DAASIPGDG--LASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAML---GN 1171 D + D L + + P L + +I+A++L D T + YVK L G Sbjct: 342 DIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGR 401 Query: 1172 QALRTRVSPGR-TLNPMWNEDLMF-VAAEPFEE-HLILSVEDRIAPGKDDVIGRTVISLQ 1342 + + + S R TLNP++NE ++F V E ++ HL ++V D G ++VIG V + Sbjct: 402 RLKKRKTSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVMDYDRVGHNEVIG--VCQVG 459 Query: 1343 HVARRL--DH 1366 + A RL DH Sbjct: 460 NEAERLGRDH 469
>Q5RCK6:SYT10_PONPY Synaptotagmin-10 - Pongo pygmaeus (Orangutan)| Length = 523 Score = 55.5 bits (132), Expect = 1e-06 Identities = 69/282 (24%), Positives = 115/282 (40%), Gaps = 12/282 (4%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL T + + L V+++KA +LP+KD TG+ DPYV++ L K TR K N Sbjct: 234 KLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLN 293 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +++ F F Q S ++ F + Y Sbjct: 294 PLFDETFQFPVAYDQLSNR----------------KLHFSV-----------------YD 320 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFPEAWHS-DAASIPGDGLASIRSKVYLTPKLWYL 1084 + + H + GE++L W A+ L I + P + Sbjct: 321 FDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRM 380 Query: 1085 RVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTR----VSPGRTLNPMWNEDLMF-VAA 1249 + VI+ ++L D T + YVK L + R + + TLNP++NE ++F + Sbjct: 381 TLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPP 440 Query: 1250 EPFEE-HLILSVEDRIAPGKDDVIG--RTVISLQHVARRLDH 1366 E ++ L ++V D G ++VIG RT + + + R DH Sbjct: 441 ENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGR--DH 480
>Q6XYQ8:SYT10_HUMAN Synaptotagmin-10 - Homo sapiens (Human)| Length = 523 Score = 55.5 bits (132), Expect = 1e-06 Identities = 69/282 (24%), Positives = 115/282 (40%), Gaps = 12/282 (4%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTN 727 KL T + + L V+++KA +LP+KD TG+ DPYV++ L K TR K N Sbjct: 234 KLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLN 293 Query: 728 PEWNQVFAFSKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYR 907 P +++ F F Q S ++ F + Y Sbjct: 294 PLFDETFQFPVAYDQLSNR----------------KLHFSV-----------------YD 320 Query: 908 LEERNGHKVKGELMLAVWMGTQADEAFPEAWHS-DAASIPGDGLASIRSKVYLTPKLWYL 1084 + + H + GE++L W A+ L I + P + Sbjct: 321 FDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRM 380 Query: 1085 RVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTR----VSPGRTLNPMWNEDLMF-VAA 1249 + VI+ ++L D T + YVK L + R + + TLNP++NE ++F + Sbjct: 381 TLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPP 440 Query: 1250 EPFEE-HLILSVEDRIAPGKDDVIG--RTVISLQHVARRLDH 1366 E ++ L ++V D G ++VIG RT + + + R DH Sbjct: 441 ENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGR--DH 480
>P21521:SY65_DROME Synaptotagmin - Drosophila melanogaster (Fruit fly)| Length = 474 Score = 55.5 bits (132), Expect = 1e-06 Identities = 67/271 (24%), Positives = 107/271 (39%), Gaps = 15/271 (5%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFSKERI 769 L V V++A+ELP+ D+ G+ DPYV+V L K T+ K +P +N+ F F Sbjct: 209 LAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTF----- 263 Query: 770 QASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGELM 949 +P + L + + + H GE+ Sbjct: 264 ---------------------------KSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVK 296 Query: 950 LAVWMGTQADEAFPEAWHSDAASIPGDG----LASIRSKVYLTPKLWYLRVNVIEAQDLI 1117 + + A E W D S+ G+G L I + P L V ++EA++L Sbjct: 297 VPLCTIDLAQTI--EEWR-DLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLK 353 Query: 1118 PNDKTRFPEVYVKAML---GNQALRTRVSPGR-TLNPMWNEDLMFVAAEPFEEH----LI 1273 D + YVK + G + + + S + TLNP +NE F PFE+ L+ Sbjct: 354 KMDVGGLSDPYVKIAIMQNGKRLKKKKTSVKKCTLNPYYNESFSFEV--PFEQMQKICLV 411 Query: 1274 LSVEDRIAPGKDDVIGRTVISLQHVARRLDH 1366 ++V D G + IGR ++ L H Sbjct: 412 VTVVDYDRIGTSEPIGRCILGCMGTGTELRH 442
>P41885:RBF1_CAEEL Rabphilin-1 - Caenorhabditis elegans| Length = 1106 Score = 55.5 bits (132), Expect = 1e-06 Identities = 71/298 (23%), Positives = 119/298 (39%), Gaps = 15/298 (5%) Frame = +2 Query: 488 PFRPEEYSLKETTPHLG--GAAAGDKLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCD 661 P EE ++ +T G+ LT TY ++ L + +++AK L + D G D Sbjct: 807 PEEEEEKAITASTESASEPGSLGSITLTLTYHSADKK--LKMHLIRAKNLKAMDSNGFSD 864 Query: 662 PYVEVKL--GNYKG---TTRHFEKKTNPEWNQVFAFSKERIQASXXXXXXXXXXXXXXXX 826 PYV+ L GN K T++ EK NPEWN+ ++ Sbjct: 865 PYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSY------------YGITEDDKEKKI 912 Query: 827 XGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGELMLAVWMGTQADEAFPEAWHS 1006 + D + + ++ +A L++ N +++K + A P + Sbjct: 913 LRVTVLDRDRIGSDFLGETRIA-----LKKLNDNEMKK-------FNLYLESALPVPQQT 960 Query: 1007 DAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQA 1177 G ++ + + ++ +N +L+ D T F + Y K L ++A Sbjct: 961 KEEENEDRGKINVGLQYNIQQGSLFININ--RCVELVGMDSTGFSDPYCKVSLTPITSKA 1018 Query: 1178 LRTRVS-PGRTLNPMWNEDLMFVAAEPFEE----HLILSVEDRIAPGKDDVIGRTVIS 1336 R + S RTLNP WNE L FV PF++ L + V D DD IG ++S Sbjct: 1019 HRAKTSTKKRTLNPEWNEQLQFVV--PFKDLPKKTLQIGVYDHDLGKHDDYIGGILLS 1074 Score = 48.5 bits (114), Expect = 2e-04 Identities = 78/278 (28%), Positives = 114/278 (41%), Gaps = 19/278 (6%) Frame = +2 Query: 1004 SDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAML--GNQA 1177 +++AS PG L SI + L++++I A++L D F + YVK L GN Sbjct: 819 TESASEPGS-LGSITLTLTYHSADKKLKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTK 877 Query: 1178 LRTRVSPG--RTLNPMWNEDLMFVA-AEPFEEHLILSV----EDRIAPGKDDVIGRTVIS 1336 S +TLNP WNE++ + E +E IL V DRI D +G T I+ Sbjct: 878 ATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDRDRIG---SDFLGETRIA 934 Query: 1337 LQHVARRLDHKLLNSQWYNLEKHVMVDGEQRKETKFSSRIHLRICLEGGYHVLDESTHYS 1516 L K LN D E +K + LE V ++ Sbjct: 935 L---------KKLN------------DNEMKK---------FNLYLESALPVPQQTKEEE 964 Query: 1517 SDLRPTAKQLWKHNI--GVLELGILTAQGLLPMKTKDGRGTTDPYC---VAKYGQKWVRT 1681 ++ R ++NI G L + I L+ M D G +DPYC + K R Sbjct: 965 NEDRGKINVGLQYNIQQGSLFININRCVELVGM---DSTGFSDPYCKVSLTPITSKAHRA 1021 Query: 1682 RTIIDSFT--PKWNEQYTWEV---HDPCTVITIGVFDN 1780 +T T P+WNEQ + V P + IGV+D+ Sbjct: 1022 KTSTKKRTLNPEWNEQLQFVVPFKDLPKKTLQIGVYDH 1059
>O08625:SYT10_RAT Synaptotagmin-10 - Rattus norvegicus (Rat)| Length = 523 Score = 55.1 bits (131), Expect = 2e-06 Identities = 66/270 (24%), Positives = 112/270 (41%), Gaps = 12/270 (4%) Frame = +2 Query: 593 QYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFSKE 763 + L V+++KA +LP+KD TG+ DPYV++ L K TR K NP ++++F F Sbjct: 246 ELLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVV 305 Query: 764 RIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGE 943 Q S ++ F + Y + + H + GE Sbjct: 306 YDQLSNR----------------KLHFSI-----------------YDFDRFSRHDMIGE 332 Query: 944 LMLAVWMGTQADEAFPEAWHS-DAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIP 1120 ++L W A+ L I + P + + VI+ ++L Sbjct: 333 VILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKA 392 Query: 1121 NDKTRFPEVYVKAMLGNQALRTR----VSPGRTLNPMWNEDLMF-VAAEPFEE-HLILSV 1282 D T + YVK L + R + + TLNP++NE ++F + E ++ L ++V Sbjct: 393 MDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAV 452 Query: 1283 EDRIAPGKDDVIG--RTVISLQHVARRLDH 1366 D G ++VIG RT + + + R DH Sbjct: 453 MDYDRVGHNEVIGVCRTGLDAEGLGR--DH 480
>Q9R0N4:SYT10_MOUSE Synaptotagmin-10 - Mus musculus (Mouse)| Length = 523 Score = 55.1 bits (131), Expect = 2e-06 Identities = 66/270 (24%), Positives = 112/270 (41%), Gaps = 12/270 (4%) Frame = +2 Query: 593 QYLYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFSKE 763 + L V+++KA +LP+KD TG+ DPYV++ L K TR K NP ++++F F Sbjct: 246 ELLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVV 305 Query: 764 RIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGE 943 Q S ++ F + Y + + H + GE Sbjct: 306 YDQLSNR----------------KLHFSI-----------------YDFDRFSRHDMIGE 332 Query: 944 LMLAVWMGTQADEAFPEAWHS-DAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIP 1120 ++L W A+ L I + P + + VI+ ++L Sbjct: 333 VILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKA 392 Query: 1121 NDKTRFPEVYVKAMLGNQALRTR----VSPGRTLNPMWNEDLMF-VAAEPFEE-HLILSV 1282 D T + YVK L + R + + TLNP++NE ++F + E ++ L ++V Sbjct: 393 MDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAV 452 Query: 1283 EDRIAPGKDDVIG--RTVISLQHVARRLDH 1366 D G ++VIG RT + + + R DH Sbjct: 453 MDYDRVGHNEVIGVCRTGLDAEGLGR--DH 480
>Q5RJH2:MCTP2_MOUSE Multiple C2 and transmembrane domain-containing protein 2 - Mus| musculus (Mouse) Length = 878 Score = 54.3 bits (129), Expect = 3e-06 Identities = 32/102 (31%), Positives = 56/102 (54%) Frame = +2 Query: 1556 NIGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWE 1735 ++G+L++ +L A LL D G +DP+C+ + G ++T TI + P+WN+ +T+ Sbjct: 507 DVGILQVKVLKASDLL---AADFSGKSDPFCLLELGNDRLQTHTIYKNLNPEWNKVFTFP 563 Query: 1736 VHDPCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTL 1861 + D V+ + VFD G+KA +GKV I L ++ Sbjct: 564 IKDIHDVLEVTVFD----EDGDKA----PDFLGKVAIPLLSI 597 Score = 53.1 bits (126), Expect = 7e-06 Identities = 60/277 (21%), Positives = 114/277 (41%), Gaps = 11/277 (3%) Frame = +2 Query: 1064 TPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFV 1243 +P + L +++ E ++L+ D+ + YVK L + L + LNP+W+E ++ + Sbjct: 190 SPFAYLLTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKTLYKSKVIYKNLNPIWDE-IVVL 248 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISL---------QHVARRLDHKLLNSQW--Y 1390 + ++ L + V DR K D +G + L +H+ + D L Sbjct: 249 PIQSLDQKLRVKVYDRDLT-KSDFMGSAFVVLRDLELNRTTEHILKLEDPNSLEDDMGVI 307 Query: 1391 NLEKHVMVDGEQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVL 1570 L +++V K ++S+R L L + S LR QLW I + Sbjct: 308 VLNLNLVVKQGDFKRHRWSNRKR----LSASKSSLIRNLRLSESLR--KNQLWNGIISIT 361 Query: 1571 ELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDPC 1750 LL K G T+ + K G++ +++T+ S P+W EQ+ + Sbjct: 362 ---------LLEGKNVSGGNMTEMFVQLKLGEQRYKSKTLCKSANPQWQEQFDFHYFSD- 411 Query: 1751 TVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTL 1861 +G+ D + K + + R+G ++ +S L Sbjct: 412 ---RMGILD---IEVWGKDSKKHEERLGTCKVDISAL 442 Score = 51.6 bits (122), Expect = 2e-05 Identities = 24/58 (41%), Positives = 36/58 (62%) Frame = +2 Query: 581 VEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF 754 V+ + L V+V+KA +L + D +G DP+ ++LGN + T K NPEWN+VF F Sbjct: 505 VKDVGILQVKVLKASDLLAADFSGKSDPFCLLELGNDRLQTHTIYKNLNPEWNKVFTF 562 Score = 43.9 bits (102), Expect = 0.004 Identities = 30/123 (24%), Positives = 56/123 (45%) Frame = +1 Query: 2335 YNLPLLFLIGVWYYRWRSRQPPHMDTRLSHAETAHPDELDEEFDTFPTSRPPDIVRMRYD 2514 Y +PL L+ Y R + T+ S T +E EE S I+ Y Sbjct: 707 YMIPLALLLLFLYNFLRPMKGKASSTQDSQESTDVEEEGKEEEKE---SEKKGIIERIY- 762 Query: 2515 RLRSVAGRIQTVVGDLATQGERLQSLLSWRDPRATALFVTFCFIAAIVLYVTPFRVVVFL 2694 ++ + +Q ++ ++A+ GER++++ +W P + L I ++LY P R ++ L Sbjct: 763 MVQDIVSTVQNILEEVASFGERIKNVFNWTVPFLSLLACLILAITTVILYFIPLRYIILL 822 Query: 2695 AGL 2703 G+ Sbjct: 823 WGI 825 Score = 34.7 bits (78), Expect = 2.5 Identities = 25/86 (29%), Positives = 42/86 (48%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFE 1261 L+V V++A DL+ D + + + LGN L+T + + LNP WN+ F + Sbjct: 511 LQVKVLKASDLLAADFSGKSDPFCLLELGNDRLQTH-TIYKNLNPEWNKVFTF-PIKDIH 568 Query: 1262 EHLILSVEDRIAPGKDDVIGRTVISL 1339 + L ++V D D +G+ I L Sbjct: 569 DVLEVTVFDEDGDKAPDFLGKVAIPL 594
>Q3TZZ7:FA62B_MOUSE Protein FAM62B - Mus musculus (Mouse)| Length = 845 Score = 52.4 bits (124), Expect = 1e-05 Identities = 56/241 (23%), Positives = 100/241 (41%), Gaps = 11/241 (4%) Frame = +2 Query: 599 LYVRVVKAKELPSKD------LTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSK 760 L + ++A++L KD + G DPY +++GN ++ ++ +P+WN+V+ Sbjct: 311 LRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVGNQIFQSKVIKENLSPKWNEVYEALV 370 Query: 761 ERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKG 940 G +M DL EV K L +W+ L+E KG Sbjct: 371 YEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEK-----ERLLDEWFTLDE----VPKG 421 Query: 941 ELMLAV-WMGTQADEAFPEAWHSDAAS---IPGDGLASIRSKVYLTPKLWYLRVNVIEAQ 1108 +L L + W+ D A + +D + DGL+S +YL A+ Sbjct: 422 KLHLKLEWLTLMPDAANLDKVLADIRADKDQASDGLSSALLILYLD-----------SAR 470 Query: 1109 DLIPNDKTRF-PEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVE 1285 +L K P V+ +G++A +++ +T P+W E+ F P + L + V+ Sbjct: 471 NLPSGKKINSNPNPLVQMSVGHKAQESKIR-YKTSEPVWEENFTFFIHNPRRQDLEVEVK 529 Query: 1286 D 1288 D Sbjct: 530 D 530 Score = 41.2 bits (95), Expect = 0.026 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 4/116 (3%) Frame = +2 Query: 1562 GVLELGILTAQGLLPMKTKDG---RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTW 1732 GVL + + AQ L T +G +DPY + + G + +++ I ++ +PKWNE Y Sbjct: 309 GVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVGNQIFQSKVIKENLSPKWNEVYEA 368 Query: 1733 EVHD-PCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPL 1897 V++ P + I +FD + +D +G + I L +E +R+ + L Sbjct: 369 LVYEHPGQELEIELFDE---------DPDKDDFLGSLMIDLIEVEKERLLDEWFTL 415
>Q9Z1N9:UN13B_MOUSE Unc-13 homolog B - Mus musculus (Mouse)| Length = 1591 Score = 51.2 bits (121), Expect = 3e-05 Identities = 47/171 (27%), Positives = 76/171 (44%), Gaps = 22/171 (12%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMF------- 1240 + + V+ AQ L DKT + YV +G RT+ G LNP+W E F Sbjct: 602 ITITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIFG-NLNPVWEEKFHFECHNSSD 660 Query: 1241 ---VAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVM 1411 V ++ + V+ R+ DD +G+T+I ++ ++ +D WYNLEK Sbjct: 661 RIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMD------VWYNLEK--- 711 Query: 1412 VDGEQRKETKFSSRIHLRICLE-------GGYHV----LDEST-HYSSDLR 1528 + ++ S I L+I +E YHV L E+ HY +D++ Sbjct: 712 ----RTDKSAVSGAIRLQISVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQ 758 Score = 50.1 bits (118), Expect = 6e-05 Identities = 32/97 (32%), Positives = 49/97 (50%) Frame = +2 Query: 1487 HVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQ 1666 HV T S L T+K W I + ++ AQGL + KD G++DPY + G+ Sbjct: 580 HVQQMKTVKQSVLDGTSK--WSAKITIT---VVCAQGL---QAKDKTGSSDPYVTVQVGK 631 Query: 1667 KWVRTRTIIDSFTPKWNEQYTWEVHDPCTVITIGVFD 1777 RT+TI + P W E++ +E H+ I + V+D Sbjct: 632 TKKRTKTIFGNLNPVWEEKFHFECHNSSDRIKVRVWD 668 Score = 44.7 bits (104), Expect = 0.002 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 4/60 (6%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF----SKERIQ 772 + VV A+ L +KD TGS DPYV V++G K T+ NP W + F F S +RI+ Sbjct: 604 ITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIFGNLNPVWEEKFHFECHNSSDRIK 663
>Q62768:UN13A_RAT Unc-13 homolog A - Rattus norvegicus (Rat)| Length = 1735 Score = 51.2 bits (121), Expect = 3e-05 Identities = 38/155 (24%), Positives = 67/155 (43%), Gaps = 10/155 (6%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMF------- 1240 + + V+ AQ L DKT + YV +G RT+ G LNP+W E+ F Sbjct: 691 ISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYG-NLNPVWEENFHFECHNSSD 749 Query: 1241 ---VAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVM 1411 V ++ + V+ R DD +G+T+I ++ ++ +D WYNL+K Sbjct: 750 RIKVRVLDEDDDIKSRVKQRFKRESDDFLGQTIIEVRTLSGEMD------VWYNLDKRT- 802 Query: 1412 VDGEQRKETKFSSRIHLRICLEGGYHVLDESTHYS 1516 + + R+H+ + ++G V Y+ Sbjct: 803 ----DKSAVSGAIRLHISVEIKGEEKVAPYHVQYT 833 Score = 47.4 bits (111), Expect = 4e-04 Identities = 23/70 (32%), Positives = 38/70 (54%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDP 1747 + + ++ AQGL + KD G++DPY + G+ RT+TI + P W E + +E H+ Sbjct: 691 ISITVVCAQGL---QAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNS 747 Query: 1748 CTVITIGVFD 1777 I + V D Sbjct: 748 SDRIKVRVLD 757 Score = 44.7 bits (104), Expect = 0.002 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 4/60 (6%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF----SKERIQ 772 + VV A+ L +KD TGS DPYV V++G K T+ NP W + F F S +RI+ Sbjct: 693 ITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRIK 752
>Q9UPW8:UN13A_HUMAN Unc-13 homolog A - Homo sapiens (Human)| Length = 1703 Score = 51.2 bits (121), Expect = 3e-05 Identities = 38/155 (24%), Positives = 67/155 (43%), Gaps = 10/155 (6%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMF------- 1240 + + V+ AQ L DKT + YV +G RT+ G LNP+W E+ F Sbjct: 678 ISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYG-NLNPVWEENFHFECHNSSD 736 Query: 1241 ---VAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVM 1411 V ++ + V+ R DD +G+T+I ++ ++ +D WYNL+K Sbjct: 737 RIKVRVWDEDDDIKSRVKQRFKRESDDFLGQTIIEVRTLSGEMD------VWYNLDKRT- 789 Query: 1412 VDGEQRKETKFSSRIHLRICLEGGYHVLDESTHYS 1516 + + R+H+ + ++G V Y+ Sbjct: 790 ----DKSAVSGAIRLHISVEIKGEEKVAPYHVQYT 820 Score = 47.8 bits (112), Expect = 3e-04 Identities = 23/70 (32%), Positives = 39/70 (55%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDP 1747 + + ++ AQGL + KD G++DPY + G+ RT+TI + P W E + +E H+ Sbjct: 678 ISITVVCAQGL---QAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNS 734 Query: 1748 CTVITIGVFD 1777 I + V+D Sbjct: 735 SDRIKVRVWD 744 Score = 44.7 bits (104), Expect = 0.002 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 4/60 (6%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF----SKERIQ 772 + VV A+ L +KD TGS DPYV V++G K T+ NP W + F F S +RI+ Sbjct: 680 ITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRIK 739
>Q62769:UN13B_RAT Unc-13 homolog B - Rattus norvegicus (Rat)| Length = 1622 Score = 50.4 bits (119), Expect = 4e-05 Identities = 47/171 (27%), Positives = 76/171 (44%), Gaps = 22/171 (12%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMF------- 1240 + + V+ AQ L DKT + YV +G RT+ G LNP+W E F Sbjct: 615 ITITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIFG-NLNPVWEEKFHFECHNSSD 673 Query: 1241 ---VAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVM 1411 V ++ + V+ R+ DD +G+T+I ++ ++ +D WYNLEK Sbjct: 674 RIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMD------VWYNLEK--- 724 Query: 1412 VDGEQRKETKFSSRIHLRICLE-------GGYHV----LDEST-HYSSDLR 1528 + ++ S I L+I +E YHV L E+ HY +D++ Sbjct: 725 ----RTDKSAVSGAIRLQINVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQ 771 Score = 50.1 bits (118), Expect = 6e-05 Identities = 32/97 (32%), Positives = 49/97 (50%) Frame = +2 Query: 1487 HVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQ 1666 HV T S L T+K W I + ++ AQGL + KD G++DPY + G+ Sbjct: 593 HVQQMKTVKQSVLDGTSK--WSAKITIT---VVCAQGL---QAKDKTGSSDPYVTVQVGK 644 Query: 1667 KWVRTRTIIDSFTPKWNEQYTWEVHDPCTVITIGVFD 1777 RT+TI + P W E++ +E H+ I + V+D Sbjct: 645 TKKRTKTIFGNLNPVWEEKFHFECHNSSDRIKVRVWD 681 Score = 44.7 bits (104), Expect = 0.002 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 4/60 (6%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF----SKERIQ 772 + VV A+ L +KD TGS DPYV V++G K T+ NP W + F F S +RI+ Sbjct: 617 ITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIFGNLNPVWEEKFHFECHNSSDRIK 676
>O14065:YC31_SCHPO Uncharacterized protein C962.01 - Schizosaccharomyces pombe (Fission| yeast) Length = 1429 Score = 50.1 bits (118), Expect = 6e-05 Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 4/124 (3%) Frame = +2 Query: 1022 PGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPND-KTRFPEVYVKAMLGNQALRTRVSP 1198 P D + +K Y+ + +R++VI+A DL+ + TR + Y + ++GN + V Sbjct: 739 PVDVVEEKSAKTYIDNLVGVMRLSVIKANDLVNVELPTRKSDPYARVIVGNSVVARTVYT 798 Query: 1199 GRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHV---ARRLDHK 1369 LNP+WNE +++V + + L D G D +G I++Q A+RLD Sbjct: 799 PNNLNPIWNE-ILYVPIMADTKTIDLEAMDYEESGNDRSLGYASINVQKYIRNAKRLDRS 857 Query: 1370 LLNS 1381 L S Sbjct: 858 ALAS 861
>Q8K0T7:UN13C_MOUSE Unc-13 homolog C - Mus musculus (Mouse)| Length = 2210 Score = 50.1 bits (118), Expect = 6e-05 Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 10/142 (7%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMF------- 1240 + + V+ AQ L DKT + YV +G RT+ G LNP+W+E F Sbjct: 1218 ITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFG-NLNPVWDEKFFFECHNSTD 1276 Query: 1241 ---VAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVM 1411 V ++ + V+ DD +G+T++ ++ ++ +D WYNLEK Sbjct: 1277 RIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEVRTLSGEMD------VWYNLEK--- 1327 Query: 1412 VDGEQRKETKFSSRIHLRICLE 1477 + ++ S I L+I +E Sbjct: 1328 ----RTDKSAVSGAIRLKINVE 1345 Score = 49.3 bits (116), Expect = 1e-04 Identities = 23/70 (32%), Positives = 42/70 (60%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDP 1747 + + +++AQGL + KD G++DPY + G+ RT+TI + P W+E++ +E H+ Sbjct: 1218 ITITVVSAQGL---QAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFFFECHNS 1274 Query: 1748 CTVITIGVFD 1777 I + V+D Sbjct: 1275 TDRIKVRVWD 1284 Score = 45.8 bits (107), Expect = 0.001 Identities = 22/50 (44%), Positives = 30/50 (60%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF 754 + VV A+ L +KD TGS DPYV V++G K T+ NP W++ F F Sbjct: 1220 ITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFFF 1269 Score = 40.8 bits (94), Expect = 0.035 Identities = 41/150 (27%), Positives = 58/150 (38%), Gaps = 11/150 (7%) Frame = +2 Query: 1001 HSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLG---- 1168 H D + PG G + V VI DL F MLG Sbjct: 2045 HVDVTTTPGTGDHKVT-------------VKVIAINDLNWQTTAMFRPFVEVCMLGPSLG 2091 Query: 1169 ----NQALRTRVSPGRTLNPMWNEDLMFVAAE---PFEEHLILSVEDRIAPGKDDVIGRT 1327 Q +T+ T +P +NE F+ P L LSV+D +D +IG T Sbjct: 2092 DKKRKQGTKTK---SNTWSPKYNETFQFILGNENRPGAYELHLSVKDYCFAREDRIIGMT 2148 Query: 1328 VISLQHVARRLDHKLLNSQWYNLEKHVMVD 1417 VI LQ++A + + WY L K++ +D Sbjct: 2149 VIQLQNIAEKGSY----GAWYPLLKNLSMD 2174
>Q62770:UN13C_RAT Unc-13 homolog C - Rattus norvegicus (Rat)| Length = 2204 Score = 49.7 bits (117), Expect = 7e-05 Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 10/142 (7%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMF------- 1240 + + V+ AQ L DKT + YV +G RT+ G LNP+W+E F Sbjct: 1212 ITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFG-NLNPVWDEKFYFECHNSTD 1270 Query: 1241 ---VAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVM 1411 V ++ + V+ DD +G+T++ ++ ++ +D WYNLEK Sbjct: 1271 RIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEVRTLSGEMD------VWYNLEK--- 1321 Query: 1412 VDGEQRKETKFSSRIHLRICLE 1477 + ++ S I L+I +E Sbjct: 1322 ----RTDKSAVSGAIRLKINVE 1339 Score = 49.3 bits (116), Expect = 1e-04 Identities = 23/70 (32%), Positives = 42/70 (60%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDP 1747 + + +++AQGL + KD G++DPY + G+ RT+TI + P W+E++ +E H+ Sbjct: 1212 ITITVVSAQGL---QAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFYFECHNS 1268 Query: 1748 CTVITIGVFD 1777 I + V+D Sbjct: 1269 TDRIKVRVWD 1278 Score = 45.8 bits (107), Expect = 0.001 Identities = 22/50 (44%), Positives = 30/50 (60%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF 754 + VV A+ L +KD TGS DPYV V++G K T+ NP W++ F F Sbjct: 1214 ITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFYF 1263 Score = 43.1 bits (100), Expect = 0.007 Identities = 42/150 (28%), Positives = 59/150 (39%), Gaps = 11/150 (7%) Frame = +2 Query: 1001 HSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLG---- 1168 H D + PG G + V VI DL T F MLG Sbjct: 2039 HVDVTTTPGTGEHKVT-------------VKVIAINDLNWQTTTMFRPFVEVCMLGPSLG 2085 Query: 1169 ----NQALRTRVSPGRTLNPMWNEDLMFVAAE---PFEEHLILSVEDRIAPGKDDVIGRT 1327 Q +T+ T +P +NE F+ P L LSV+D +D +IG T Sbjct: 2086 DKKRKQGTKTK---SNTWSPKYNETFQFILGNENRPGAYELHLSVKDYCFAREDRIIGMT 2142 Query: 1328 VISLQHVARRLDHKLLNSQWYNLEKHVMVD 1417 VI LQ++A + + WY L K++ +D Sbjct: 2143 VIQLQNIAEKGSY----GAWYPLLKNLSMD 2168
>Q8NB66:UN13C_HUMAN Unc-13 homolog C - Homo sapiens (Human)| Length = 2214 Score = 49.7 bits (117), Expect = 7e-05 Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 10/142 (7%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMF------- 1240 + + V+ AQ L DKT + YV +G RT+ G LNP+W+E F Sbjct: 1222 ITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFG-NLNPVWDEKFYFECHNSTD 1280 Query: 1241 ---VAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVM 1411 V ++ + V+ DD +G+T++ ++ ++ +D WYNLEK Sbjct: 1281 RIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEVRTLSGEMD------VWYNLEK--- 1331 Query: 1412 VDGEQRKETKFSSRIHLRICLE 1477 + ++ S I L+I +E Sbjct: 1332 ----RTDKSAVSGAIRLKINVE 1349 Score = 49.3 bits (116), Expect = 1e-04 Identities = 23/70 (32%), Positives = 42/70 (60%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDP 1747 + + +++AQGL + KD G++DPY + G+ RT+TI + P W+E++ +E H+ Sbjct: 1222 ITITVVSAQGL---QAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFYFECHNS 1278 Query: 1748 CTVITIGVFD 1777 I + V+D Sbjct: 1279 TDRIKVRVWD 1288 Score = 45.8 bits (107), Expect = 0.001 Identities = 22/50 (44%), Positives = 30/50 (60%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF 754 + VV A+ L +KD TGS DPYV V++G K T+ NP W++ F F Sbjct: 1224 ITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFYF 1273 Score = 41.6 bits (96), Expect = 0.020 Identities = 42/148 (28%), Positives = 63/148 (42%), Gaps = 9/148 (6%) Frame = +2 Query: 1001 HSDAASIPGDGLASIRSKVYLTPKLWYLRVNV----IEAQDLIPN--DKTRFPEVYVKAM 1162 H D + PG G + KV L + + +E L PN DK R Sbjct: 2049 HVDITATPGTGDHKVTVKVIAINDLNWQTTAMFRPFVEVCILGPNLGDKKR--------- 2099 Query: 1163 LGNQALRTRVSPGRTLNPMWNEDLMFVAAE---PFEEHLILSVEDRIAPGKDDVIGRTVI 1333 Q +T+ T +P +NE F+ + P L LSV+D +D +IG TVI Sbjct: 2100 --KQGTKTK---SNTWSPKYNETFQFILGKENRPGAYELHLSVKDYCFAREDRIIGMTVI 2154 Query: 1334 SLQHVARRLDHKLLNSQWYNLEKHVMVD 1417 LQ++A + + WY L K++ +D Sbjct: 2155 QLQNIAEKGSY----GAWYPLLKNISMD 2178
>A0FGR8:FA62B_HUMAN Protein FAM62B - Homo sapiens (Human)| Length = 921 Score = 49.7 bits (117), Expect = 7e-05 Identities = 54/242 (22%), Positives = 101/242 (41%), Gaps = 12/242 (4%) Frame = +2 Query: 599 LYVRVVKAKELPSKD------LTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSK 760 L + ++A++L KD + G DPY +++GN +R ++ +P+WN+V+ Sbjct: 387 LRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVGNQIFQSRVIKENLSPKWNEVYEALV 446 Query: 761 ERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKG 940 G +M DL EV K L +W+ L+E KG Sbjct: 447 YEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEK-----ERLLDEWFTLDE----VPKG 497 Query: 941 ELMLAV-WMGTQADEAFPEAWHSDAAS---IPGDGLASIRSKVYLTPKLWYLRVNVIEAQ 1108 +L L + W+ + + + +D + DGL+S +YL ++ Sbjct: 498 KLHLRLEWLTLMPNASNLDKVLTDIKADKDQANDGLSSALLILYL------------DSA 545 Query: 1109 DLIPNDK--TRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSV 1282 +P+ K + P V+ +G++A +++ +T P+W E+ F P + L + V Sbjct: 546 RNLPSGKKISSNPNPVVQMSVGHKAQESKIR-YKTNEPVWEENFTFFIHNPKRQDLEVEV 604 Query: 1283 ED 1288 D Sbjct: 605 RD 606 Score = 42.4 bits (98), Expect = 0.012 Identities = 32/116 (27%), Positives = 56/116 (48%), Gaps = 4/116 (3%) Frame = +2 Query: 1562 GVLELGILTAQGLLPMKTKDG---RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTW 1732 GVL + + AQ L T +G +DPY + + G + ++R I ++ +PKWNE Y Sbjct: 385 GVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVGNQIFQSRVIKENLSPKWNEVYEA 444 Query: 1733 EVHD-PCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPL 1897 V++ P + I +FD + +D +G + I L +E +R+ + L Sbjct: 445 LVYEHPGQELEIELFDE---------DPDKDDFLGSLMIDLIEVEKERLLDEWFTL 491
>Q9Y6V0:PCLO_HUMAN Protein piccolo - Homo sapiens (Human)| Length = 5183 Score = 49.3 bits (116), Expect = 1e-04 Identities = 37/130 (28%), Positives = 57/130 (43%), Gaps = 9/130 (6%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKK 721 KL YDL L + +++A+ L +D G DP+V+V L YK T+H +K Sbjct: 4570 KLQINYDLGN----LIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGAEYKRRTKHVQKS 4625 Query: 722 TNPEWNQVFAF---SKERI-QASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPL 889 NPEWNQ + S E++ + + G V+ DL+ Sbjct: 4626 LNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSST-----SHLDN 4680 Query: 890 APQWYRLEER 919 P+WY L+E+ Sbjct: 4681 TPRWYPLKEQ 4690 Score = 42.0 bits (97), Expect = 0.015 Identities = 31/125 (24%), Positives = 65/125 (52%), Gaps = 7/125 (5%) Frame = +2 Query: 1049 SKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTLNP 1216 SK+ + L L +++++A++L+P D + + +VK L G + R ++LNP Sbjct: 4569 SKLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGAEYKRRTKHVQKSLNP 4628 Query: 1217 MWNEDLMF--VAAEPFEEH-LILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQW 1387 WN+ +++ ++ E ++ L ++V D +D +G +I L + LD+ +W Sbjct: 4629 EWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS-HLDN---TPRW 4684 Query: 1388 YNLEK 1402 Y L++ Sbjct: 4685 YPLKE 4689
>O14795:UN13B_HUMAN Unc-13 homolog B - Homo sapiens (Human)| Length = 1591 Score = 48.9 bits (115), Expect = 1e-04 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 22/171 (12%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMF------- 1240 + + V+ AQ L DKT + YV + RT+ G LNP+W E F Sbjct: 602 ITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTKTIFGN-LNPVWEEKFHFECHNSSD 660 Query: 1241 ---VAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVM 1411 V ++ + V+ R+ DD +G+T+I ++ ++ +D WYNLEK Sbjct: 661 RIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMD------VWYNLEK--- 711 Query: 1412 VDGEQRKETKFSSRIHLRICLE-------GGYHV----LDEST-HYSSDLR 1528 + ++ S I L+I +E YHV L E+ HY +D++ Sbjct: 712 ----RTDKSAVSGAIRLQISVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQ 758 Score = 47.8 bits (112), Expect = 3e-04 Identities = 31/97 (31%), Positives = 48/97 (49%) Frame = +2 Query: 1487 HVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQ 1666 HV T S L T+K W I + ++ AQGL + KD G++DPY + + Sbjct: 580 HVQQMKTVKQSVLDGTSK--WSAKITIT---VVCAQGL---QAKDKTGSSDPYVTVQVSK 631 Query: 1667 KWVRTRTIIDSFTPKWNEQYTWEVHDPCTVITIGVFD 1777 RT+TI + P W E++ +E H+ I + V+D Sbjct: 632 TKKRTKTIFGNLNPVWEEKFHFECHNSSDRIKVRVWD 668 Score = 42.4 bits (98), Expect = 0.012 Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 4/60 (6%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAF----SKERIQ 772 + VV A+ L +KD TGS DPYV V++ K T+ NP W + F F S +RI+ Sbjct: 604 ITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTKTIFGNLNPVWEEKFHFECHNSSDRIK 663
>Q9Z268:RASL1_MOUSE RasGAP-activating-like protein 1 - Mus musculus (Mouse)| Length = 799 Score = 48.9 bits (115), Expect = 1e-04 Identities = 55/213 (25%), Positives = 85/213 (39%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFE 1261 L + V+E + L D + + Y + +Q + + R+L+P W E+ F Sbjct: 7 LSIRVVEGRALPAKDVSGSSDPYCLVKVDDQVVARTATIWRSLSPFWGEEYTVHLPLDF- 65 Query: 1262 EHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQRKETK 1441 HL V D G DD+IG+ ISL A D + ++S W NL + V D E + E Sbjct: 66 HHLAFYVLDEDTVGHDDIIGK--ISLSKEAITADPRGIDS-WINLSR-VDPDAEVQGE-- 119 Query: 1442 FSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGLLPMKTKD 1621 +CL+ K L L + A+ L P +D Sbjct: 120 --------VCLD-------------------VKLLEDARGRCLRCHVRQARDLAP---RD 149 Query: 1622 GRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNE 1720 GT+DP+ +G + T TI + P W+E Sbjct: 150 ISGTSDPFARVFWGNHSLETSTIKKTRFPHWDE 182 Score = 45.1 bits (105), Expect = 0.002 Identities = 59/260 (22%), Positives = 100/260 (38%), Gaps = 7/260 (2%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGN-YKGTTRHFEKKTNPEWNQVFAFSKERIQA 775 L +RVV+ + LP+KD++GS DPY VK+ + T + +P W + Sbjct: 7 LSIRVVEGRALPAKDVSGSSDPYCLVKVDDQVVARTATIWRSLSPFWGE----------- 55 Query: 776 SXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGELMLA 955 E +P D + E+ GH +++ Sbjct: 56 --------------------------EYTVHLPLDFHHLAFYVLDEDTVGH---DDIIGK 86 Query: 956 VWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLW------YLRVNVIEAQDLI 1117 + + +A A P S D A ++ +V L KL LR +V +A+DL Sbjct: 87 ISLSKEAITADPRGIDSWINLSRVDPDAEVQGEVCLDVKLLEDARGRCLRCHVRQARDLA 146 Query: 1118 PNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIA 1297 P D + + + + GN +L T +T P W+E L A L + + D Sbjct: 147 PRDISGTSDPFARVFWGNHSLETSTIK-KTRFPHWDEVLELREAPGTTSPLRVELWDWDM 205 Query: 1298 PGKDDVIGRTVISLQHVARR 1357 GK+D +G + Q + ++ Sbjct: 206 VGKNDFLGMVEFTPQTLQQK 225 Score = 41.2 bits (95), Expect = 0.026 Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 1/117 (0%) Frame = +2 Query: 1607 MKTKDGRGTTDPYCVAKYGQKWV-RTRTIIDSFTPKWNEQYTWEVHDPCTVITIGVFDNC 1783 + KD G++DPYC+ K + V RT TI S +P W E+YT VH P F + Sbjct: 17 LPAKDVSGSSDPYCLVKVDDQVVARTATIWRSLSPFWGEEYT--VHLPLD------FHHL 68 Query: 1784 HLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLIVLTPAGVKKMGEVQLAVR 1954 ++ D IGK+ + + D S+ + + GEV L V+ Sbjct: 69 AFYVLDEDTVGHDDIIGKISLSKEAITADPRGIDSWINLSRVDPDAEVQGEVCLDVK 125
>Q9Z0R6:ITSN2_MOUSE Intersectin-2 - Mus musculus (Mouse)| Length = 1658 Score = 47.0 bits (110), Expect = 5e-04 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Frame = +2 Query: 1082 LRVNVIEAQDLI---PNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V+VIEA +L PN K+ Y + +G+Q+ TR TLNP WN + F + Sbjct: 1532 LMVHVIEATELKACKPNGKSN---PYCEVSMGSQSYTTRTLQD-TLNPKWNFNCQFFIKD 1587 Query: 1253 PFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHK 1369 +++ L L++ DR DD +GRT + + + + K Sbjct: 1588 LYQDVLCLTMFDRDQFSPDDFLGRTEVPVAKIRTEQESK 1626 Score = 41.6 bits (96), Expect = 0.020 Identities = 19/47 (40%), Positives = 27/47 (57%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWN 739 L V V++A EL + G +PY EV +G+ TTR + NP+WN Sbjct: 1532 LMVHVIEATELKACKPNGKSNPYCEVSMGSQSYTTRTLQDTLNPKWN 1578 Score = 37.7 bits (86), Expect = 0.29 Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Frame = +2 Query: 1559 IGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEV 1738 IG L + ++ A L K G ++PYC G + TRT+ D+ PKWN + + Sbjct: 1529 IGRLMVHVIEATELKACKPN---GKSNPYCEVSMGSQSYTTRTLQDTLNPKWNFNCQFFI 1585 Query: 1739 HDPC-TVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTL--ETDRVYTHSYP 1894 D V+ + +FD + + G + + K+R + T R+ H P Sbjct: 1586 KDLYQDVLCLTMFDRDQFSPDDFL-GRTEVPVAKIRTEQESKGPTTRRLLLHEVP 1639
>Q9NZM3:ITSN2_HUMAN Intersectin-2 - Homo sapiens (Human)| Length = 1696 Score = 47.0 bits (110), Expect = 5e-04 Identities = 33/99 (33%), Positives = 51/99 (51%), Gaps = 3/99 (3%) Frame = +2 Query: 1082 LRVNVIEAQDLI---PNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 L V+VIEA +L PN K+ Y + +G+Q+ TR TLNP WN + F + Sbjct: 1570 LMVHVIEATELKACKPNGKSN---PYCEISMGSQSYTTRTIQD-TLNPKWNFNCQFFIKD 1625 Query: 1253 PFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHK 1369 +++ L L++ DR DD +GRT I + + + K Sbjct: 1626 LYQDVLCLTLFDRDQFSPDDFLGRTEIPVAKIRTEQESK 1664 Score = 41.2 bits (95), Expect = 0.026 Identities = 18/47 (38%), Positives = 27/47 (57%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWN 739 L V V++A EL + G +PY E+ +G+ TTR + NP+WN Sbjct: 1570 LMVHVIEATELKACKPNGKSNPYCEISMGSQSYTTRTIQDTLNPKWN 1616 Score = 37.4 bits (85), Expect = 0.38 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 1/106 (0%) Frame = +2 Query: 1559 IGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEV 1738 IG L + ++ A L K G ++PYC G + TRTI D+ PKWN + + Sbjct: 1567 IGRLMVHVIEATELKACKPN---GKSNPYCEISMGSQSYTTRTIQDTLNPKWNFNCQFFI 1623 Query: 1739 HDPC-TVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDR 1873 D V+ + +FD + + D +G+ I ++ + T++ Sbjct: 1624 KDLYQDVLCLTLFD--------RDQFSPDDFLGRTEIPVAKIRTEQ 1661
>Q7ZWU7:F62BB_XENLA Protein FAM62B-B - Xenopus laevis (African clawed frog)| Length = 876 Score = 46.6 bits (109), Expect = 6e-04 Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 4/116 (3%) Frame = +2 Query: 1562 GVLELGILTAQGLLPMKTKDG---RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTW 1732 GVL + L AQ L+ T +G +DPY V + G + +++ I ++ PKWNE Y Sbjct: 317 GVLRIHFLEAQDLMWKDTYMKGLVKGKSDPYGVVRLGNQVFQSKVIKENLNPKWNEVYEA 376 Query: 1733 EVHD-PCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPL 1897 VH+ P + I +FD + +D +G + I L +E +RV + L Sbjct: 377 LVHEHPGQELEIELFDE---------DTDKDDFLGSLLIDLVEVEKERVVDEWFTL 423 Score = 44.3 bits (103), Expect = 0.003 Identities = 55/249 (22%), Positives = 91/249 (36%), Gaps = 19/249 (7%) Frame = +2 Query: 599 LYVRVVKAKELPSKD------LTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSK 760 L + ++A++L KD + G DPY V+LGN ++ ++ NP+WN+V+ Sbjct: 319 LRIHFLEAQDLMWKDTYMKGLVKGKSDPYGVVRLGNQVFQSKVIKENLNPKWNEVYEALV 378 Query: 761 ERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKG 940 G ++ DL EV K D +W+ L+E K+ Sbjct: 379 HEHPGQELEIELFDEDTDKDDFLGSLLIDLVEVEKERVVD-----EWFTLDEATSGKL-- 431 Query: 941 ELMLAVWMGTQADEAFPEAWHSDAA--SIPGDGLASIRSKVYLTPKLWY----LRVN--- 1093 L L E + S A DGL++ +YL L +N Sbjct: 432 HLKLEWLTPKSTTENLDQVLKSIKADKDQANDGLSAALLILYLDSARSLPNNPLEINHDG 491 Query: 1094 ----VIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFE 1261 +E P YV +G+ ++V +T P+W + F P Sbjct: 492 MKKAAVEKAKKAGKKIGSSPNPYVLFSVGHTVQESKVK-YKTAEPVWEQTFTFFVHNPKR 550 Query: 1262 EHLILSVED 1288 + L + V+D Sbjct: 551 QDLEVEVKD 559 Score = 39.3 bits (90), Expect = 0.10 Identities = 62/275 (22%), Positives = 112/275 (40%), Gaps = 15/275 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDK------TRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFV 1243 LR++ +EAQDL+ D + Y LGNQ +++V LNP WNE + Sbjct: 319 LRIHFLEAQDLMWKDTYMKGLVKGKSDPYGVVRLGNQVFQSKVIK-ENLNPKWNEVYEAL 377 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGE 1423 E + L + + D KDD +G +I L V + + + +W+ L++ Sbjct: 378 VHEHPGQELEIELFDE-DTDKDDFLGSLLIDLVEV----EKERVVDEWFTLDEATSGKLH 432 Query: 1424 QRKE--TKFSSRIHLRICLEGGYHVLDESTHYSSD-----LRPTAKQLWKHNIGVLELGI 1582 + E T S+ +L L+ D++ S +A+ L + + + G+ Sbjct: 433 LKLEWLTPKSTTENLDQVLKSIKADKDQANDGLSAALLILYLDSARSLPNNPLEINHDGM 492 Query: 1583 LTAQGLLPMKTKDGRGTT-DPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDPCTV- 1756 A K G++ +PY + G ++ + P W + +T+ VH+P Sbjct: 493 KKAAVEKAKKAGKKIGSSPNPYVLFSVGHTVQESKVKYKTAEPVWEQTFTFFVHNPKRQD 552 Query: 1757 ITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTL 1861 + + V D H N +G ++I LS + Sbjct: 553 LEVEVKDENHQNS-----------MGNIKIPLSQI 576
>Q5FWL4:F62BA_XENLA Protein FAM62B-A - Xenopus laevis (African clawed frog)| Length = 872 Score = 46.6 bits (109), Expect = 6e-04 Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 4/116 (3%) Frame = +2 Query: 1562 GVLELGILTAQGLLPMKTKDG---RGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTW 1732 GVL + L AQ L+ T +G +DPY V + G + +++ I ++ PKWNE Y Sbjct: 313 GVLRIHFLEAQDLMWKDTYMKGLVKGKSDPYGVVRLGNQVFQSKVIKENLNPKWNEVYEA 372 Query: 1733 EVHD-PCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPL 1897 VH+ P + I +FD + +D +G + I L +E +RV + L Sbjct: 373 LVHEHPGQELEIELFDE---------DTDKDDFLGSLLIDLVEVEKERVVDEWFSL 419 Score = 45.1 bits (105), Expect = 0.002 Identities = 55/249 (22%), Positives = 91/249 (36%), Gaps = 19/249 (7%) Frame = +2 Query: 599 LYVRVVKAKELPSKD------LTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSK 760 L + ++A++L KD + G DPY V+LGN ++ ++ NP+WN+V+ Sbjct: 315 LRIHFLEAQDLMWKDTYMKGLVKGKSDPYGVVRLGNQVFQSKVIKENLNPKWNEVYEALV 374 Query: 761 ERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKG 940 G ++ DL EV K D +W+ L+E K+ Sbjct: 375 HEHPGQELEIELFDEDTDKDDFLGSLLIDLVEVEKERVVD-----EWFSLDEATSGKL-- 427 Query: 941 ELMLAVWMGTQADEAFPEAWHSDAA--SIPGDGLASIRSKVYLTPKLWY----LRVN--- 1093 L L + + S A DGL+S +YL L +N Sbjct: 428 HLKLEWLTPNSTTDNLDQVLKSIKADKDQANDGLSSALLILYLDSARSLPNNPLEINHDG 487 Query: 1094 ----VIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFE 1261 +E P YV +G+ ++V +T P+W + F P Sbjct: 488 MKKAAVEKAKKAGKKIGSSPNPYVLFSVGHAVQESKVK-YKTAEPLWEQTFTFFVHNPKR 546 Query: 1262 EHLILSVED 1288 + L + V+D Sbjct: 547 QDLEVEVKD 555 Score = 40.0 bits (92), Expect = 0.059 Identities = 54/236 (22%), Positives = 99/236 (41%), Gaps = 14/236 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDK------TRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFV 1243 LR++ +EAQDL+ D + Y LGNQ +++V LNP WNE + Sbjct: 315 LRIHFLEAQDLMWKDTYMKGLVKGKSDPYGVVRLGNQVFQSKVIK-ENLNPKWNEVYEAL 373 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGE 1423 E + L + + D KDD +G +I L V + + + +W++L++ Sbjct: 374 VHEHPGQELEIELFDE-DTDKDDFLGSLLIDLVEV----EKERVVDEWFSLDEATSGKLH 428 Query: 1424 QRKE--TKFSSRIHLRICLEGGYHVLDESTHYSSD-----LRPTAKQLWKHNIGVLELGI 1582 + E T S+ +L L+ D++ S +A+ L + + + G+ Sbjct: 429 LKLEWLTPNSTTDNLDQVLKSIKADKDQANDGLSSALLILYLDSARSLPNNPLEINHDGM 488 Query: 1583 LTAQGLLPMKTKDGRGTT-DPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEVHDP 1747 A K G++ +PY + G ++ + P W + +T+ VH+P Sbjct: 489 KKAAVEKAKKAGKKIGSSPNPYVLFSVGHAVQESKVKYKTAEPLWEQTFTFFVHNP 544
>Q9HC10:OTOF_HUMAN Otoferlin - Homo sapiens (Human)| Length = 1997 Score = 45.8 bits (107), Expect = 0.001 Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 1/89 (1%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSP-GRTLNPMWNEDLMFVAAEPF 1258 +RV V+ A DL P D + Y+ LG +R + + + LNP++ + A+ P Sbjct: 1494 VRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPM 1553 Query: 1259 EEHLILSVEDRIAPGKDDVIGRTVISLQH 1345 E L ++V D G DD+IG T I L++ Sbjct: 1554 ESMLTVAVYDWDLVGTDDLIGETKIDLEN 1582 Score = 34.7 bits (78), Expect = 2.5 Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 2/50 (4%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLG--NYKGTTRHFEKKTNPEWNQVF 748 V VV+A +L D+ G DPY+ ++LG + + + K+ NP + + F Sbjct: 1496 VYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSF 1545
>Q9ESF1:OTOF_MOUSE Otoferlin - Mus musculus (Mouse)| Length = 1997 Score = 45.4 bits (106), Expect = 0.001 Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 1/89 (1%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSP-GRTLNPMWNEDLMFVAAEPF 1258 +R+ V+ A DL P D + Y+ LG +R + + + LNP++ + A+ P Sbjct: 1494 VRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPM 1553 Query: 1259 EEHLILSVEDRIAPGKDDVIGRTVISLQH 1345 E L ++V D G DD+IG T I L++ Sbjct: 1554 ESMLTVAVYDWDLVGTDDLIGETKIDLEN 1582 Score = 35.4 bits (80), Expect = 1.5 Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 2/50 (4%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLG--NYKGTTRHFEKKTNPEWNQVF 748 + VV+A +L D+ G DPY+ +KLG + + + K+ NP + + F Sbjct: 1496 IYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSF 1545
>Q9PU36:PCLO_CHICK Protein piccolo - Gallus gallus (Chicken)| Length = 5120 Score = 45.1 bits (105), Expect = 0.002 Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 18/140 (12%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL--------------GNYK 694 +L YD + + L + +++A+ L +D G DP+V+V L YK Sbjct: 4616 QLQINYD--KHLGNLIIHILQARNLAPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYK 4673 Query: 695 GTTRHFEKKTNPEWNQVFAF---SKERI-QASXXXXXXXXXXXXXXXXXGRVMFDLNEVP 862 T++ +K NPEWNQ + S E++ + + G V+ DL+ V Sbjct: 4674 RRTKYVQKSLNPEWNQTVIYKNISTEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSVS 4733 Query: 863 KRVPPDSPLAPQWYRLEERN 922 + P+WY L+E++ Sbjct: 4734 Q-----LDNTPRWYPLKEQS 4748 Score = 35.4 bits (80), Expect = 1.5 Identities = 35/153 (22%), Positives = 72/153 (47%), Gaps = 16/153 (10%) Frame = +2 Query: 992 EAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAML-- 1165 EA S + I G+ I+ ++ L L +++++A++L P D + + +VK L Sbjct: 4602 EATKSGSHPITGE----IQLQINYDKHLGNLIIHILQARNLAPRDNNGYSDPFVKVYLLP 4657 Query: 1166 -----------GNQALRTRVSPGRTLNPMWNEDLMF--VAAEPFEEH-LILSVEDRIAPG 1303 + R ++LNP WN+ +++ ++ E ++ L ++V D Sbjct: 4658 GRGQVMVVQNASAEYKRRTKYVQKSLNPEWNQTVIYKNISTEQLKKKTLEVTVWDYDRFS 4717 Query: 1304 KDDVIGRTVISLQHVARRLDHKLLNSQWYNLEK 1402 +D +G +I L V+ +LD+ +WY L++ Sbjct: 4718 SNDFLGEVLIDLSSVS-QLDN---TPRWYPLKE 4746
>Q9VVI3:NEDD4_DROME E3 ubiquitin-protein ligase Nedd-4 - Drosophila melanogaster (Fruit| fly) Length = 1007 Score = 45.1 bits (105), Expect = 0.002 Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 7/124 (5%) Frame = +2 Query: 1079 YLRVNVIEAQDLIPNDKTRFPEVYVKAMLGN-------QALRTRVSPGRTLNPMWNEDLM 1237 +LR+ V+ Q L D + YV+ L ++ T+ +TLNP WNE+ + Sbjct: 71 HLRIVVLTGQSLAKKDIFGASDPYVRIDLNTINGDINIDSVLTKTKK-KTLNPTWNEEFI 129 Query: 1238 FVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVD 1417 F +P E L+ V D +DD +G ++L ++ + + + Q Y L V Sbjct: 130 F-RVKPSEHKLVFQVFDENRLTRDDFLGMVELTLVNLPTEQEGRTIGEQSYTLRPRRSVG 188 Query: 1418 GEQR 1429 + R Sbjct: 189 AKSR 192 Score = 39.7 bits (91), Expect = 0.077 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 7/60 (11%) Frame = +2 Query: 596 YLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKG-------TTRHFEKKTNPEWNQVFAF 754 +L + V+ + L KD+ G+ DPYV + L G T+ +K NP WN+ F F Sbjct: 71 HLRIVVLTGQSLAKKDIFGASDPYVRIDLNTINGDINIDSVLTKTKKKTLNPTWNEEFIF 130 Score = 32.7 bits (73), Expect = 9.4 Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 7/109 (6%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQ-------KWVRTRTIIDSFTPKWNEQY 1726 L + +LT Q L KD G +DPY V T+T + P WNE++ Sbjct: 72 LRIVVLTGQSLAK---KDIFGASDPYVRIDLNTINGDINIDSVLTKTKKKTLNPTWNEEF 128 Query: 1727 TWEVHDPCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDR 1873 + V + VFD L RD +G V + L L T++ Sbjct: 129 IFRVKPSEHKLVFQVFDENRL--------TRDDFLGMVELTLVNLPTEQ 169
>Q9JKS6:PCLO_RAT Protein piccolo - Rattus norvegicus (Rat)| Length = 5085 Score = 44.3 bits (103), Expect = 0.003 Identities = 38/155 (24%), Positives = 62/155 (40%), Gaps = 22/155 (14%) Frame = +2 Query: 521 TTPHLGGAAAGDKLTTTYDLVEQMQY----LYVRVVKAKELPSKDLTGSCDPYVEVKL-- 682 T P G AA +T L Q+ Y L + +++A+ L +D G DP+V+V L Sbjct: 4626 TKPTDGPKAASHPITGEIQL--QINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLP 4683 Query: 683 ------------GNYKGTTRHFEKKTNPEWNQVFAFS----KERIQASXXXXXXXXXXXX 814 YK T++ +K NPEWNQ + ++ ++ + Sbjct: 4684 GRGQVMVVQNASAEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLMKKTLEVTVWDYDRFS 4743 Query: 815 XXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEER 919 G V+ DL+ P+WY L+E+ Sbjct: 4744 SNDFLGEVLIDLSST-----SHLDNTPRWYPLKEQ 4773 Score = 33.1 bits (74), Expect = 7.2 Identities = 26/123 (21%), Positives = 58/123 (47%), Gaps = 16/123 (13%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML-------------GNQALRTRVSPGRTLNPMW 1222 L +++++A++L+P D + + +VK L + R ++LNP W Sbjct: 4654 LIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKYVQKSLNPEW 4713 Query: 1223 NEDLMFVA---AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYN 1393 N+ +++ + + ++ L ++V D +D +G +I L + LD+ +WY Sbjct: 4714 NQTVIYKSISMEQLMKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS-HLDN---TPRWYP 4769 Query: 1394 LEK 1402 L++ Sbjct: 4770 LKE 4772
>O95294:RASL1_HUMAN RasGAP-activating-like protein 1 - Homo sapiens (Human)| Length = 804 Score = 43.9 bits (102), Expect = 0.004 Identities = 57/252 (22%), Positives = 98/252 (38%), Gaps = 6/252 (2%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSKERIQAS 778 L VRVV+ + LP+KD++GS DPY VK+ + +T W + F E Sbjct: 7 LNVRVVEGRALPAKDVSGSSDPYCLVKVDD------EVVARTATVWRSLGPFWGE----- 55 Query: 779 XXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKVKGELMLAV 958 E +P D + E+ GH +++ + Sbjct: 56 -------------------------EYTVHLPLDFHQLAFYVLDEDTVGH---DDIIGKI 87 Query: 959 WMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLW------YLRVNVIEAQDLIP 1120 + +A A P S D A ++ ++ L+ ++ LR +V++A+DL P Sbjct: 88 SLSREAITADPRGIDSWINLSRVDPDAEVQGEICLSVQMLEDGQGRCLRCHVLQARDLAP 147 Query: 1121 NDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAP 1300 D + + + + G+Q+L T +T P W+E L L + + D Sbjct: 148 RDISGTSDPFARVFWGSQSLETSTIK-KTRFPHWDEVLELREMPGAPSPLRVELWDWDMV 206 Query: 1301 GKDDVIGRTVIS 1336 GK+D +G S Sbjct: 207 GKNDFLGMVEFS 218 Score = 39.7 bits (91), Expect = 0.077 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 1/117 (0%) Frame = +2 Query: 1607 MKTKDGRGTTDPYCVAKYGQKWV-RTRTIIDSFTPKWNEQYTWEVHDPCTVITIGVFDNC 1783 + KD G++DPYC+ K + V RT T+ S P W E+YT VH P F Sbjct: 17 LPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYT--VHLPLD------FHQL 68 Query: 1784 HLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLIVLTPAGVKKMGEVQLAVR 1954 ++ D IGK+ + + D S+ + + GE+ L+V+ Sbjct: 69 AFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEICLSVQ 125 Score = 35.0 bits (79), Expect = 1.9 Identities = 16/53 (30%), Positives = 30/53 (56%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQV 745 Q + L V++A++L +D++G+ DP+ V G+ T +K P W++V Sbjct: 131 QGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEV 183
>Q9Z0R4:ITSN1_MOUSE Intersectin-1 - Mus musculus (Mouse)| Length = 1714 Score = 43.9 bits (102), Expect = 0.004 Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 5/108 (4%) Frame = +2 Query: 1046 RSKVYLTPK-----LWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTL 1210 R K YL + L VNV+E +L P Y + +G+Q T+ TL Sbjct: 1574 REKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQD-TL 1632 Query: 1211 NPMWNEDLMFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVAR 1354 NP WN + F + +E L ++V +R DD +GRT I + + + Sbjct: 1633 NPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKK 1680 Score = 41.6 bits (96), Expect = 0.020 Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 1/106 (0%) Frame = +2 Query: 1559 IGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEV 1738 IG L + ++ L P ++ G ++PYC G + T+TI D+ PKWN + + Sbjct: 1588 IGRLMVNVVEGIELKPCRS---HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFI 1644 Query: 1739 HD-PCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDR 1873 D V+ I VF E+ + D +G+ IR++ ++ D+ Sbjct: 1645 RDLEQEVLCITVF--------ERDQFSPDDFLGRTEIRVADIKKDQ 1682 Score = 33.5 bits (75), Expect = 5.5 Identities = 17/47 (36%), Positives = 24/47 (51%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWN 739 L V VV+ EL G +PY EV +G+ T+ + NP+WN Sbjct: 1591 LMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWN 1637
>Q15811:ITSN1_HUMAN Intersectin-1 - Homo sapiens (Human)| Length = 1721 Score = 43.9 bits (102), Expect = 0.004 Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 5/108 (4%) Frame = +2 Query: 1046 RSKVYLTPK-----LWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTL 1210 R K YL + L VNV+E +L P Y + +G+Q T+ TL Sbjct: 1581 REKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQD-TL 1639 Query: 1211 NPMWNEDLMFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVAR 1354 NP WN + F + +E L ++V +R DD +GRT I + + + Sbjct: 1640 NPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKK 1687 Score = 41.6 bits (96), Expect = 0.020 Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 1/106 (0%) Frame = +2 Query: 1559 IGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEV 1738 IG L + ++ L P ++ G ++PYC G + T+TI D+ PKWN + + Sbjct: 1595 IGRLMVNVVEGIELKPCRS---HGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFI 1651 Query: 1739 HD-PCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDR 1873 D V+ I VF E+ + D +G+ IR++ ++ D+ Sbjct: 1652 RDLEQEVLCITVF--------ERDQFSPDDFLGRTEIRVADIKKDQ 1689 Score = 33.5 bits (75), Expect = 5.5 Identities = 17/47 (36%), Positives = 24/47 (51%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWN 739 L V VV+ EL G +PY EV +G+ T+ + NP+WN Sbjct: 1598 LMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWN 1644
>Q9NZM1:MYOF_HUMAN Myoferlin - Homo sapiens (Human)| Length = 2061 Score = 43.5 bits (101), Expect = 0.005 Identities = 26/97 (26%), Positives = 50/97 (51%), Gaps = 9/97 (9%) Frame = +2 Query: 1073 LWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 +++LR V +A++L+ DK F + Y +++ T + TLNP W++ ++F E Sbjct: 1138 IYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTEIIHS-TLNPTWDQTIIFDEVE 1196 Query: 1253 PFEE---------HLILSVEDRIAPGKDDVIGRTVIS 1336 + E +I+ + D GKD+ +GR++ S Sbjct: 1197 IYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFS 1233 Score = 41.6 bits (96), Expect = 0.020 Identities = 54/218 (24%), Positives = 90/218 (41%), Gaps = 15/218 (6%) Frame = +2 Query: 1067 PKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVS-PGRTLNPMWNEDLMFV 1243 P+ +R+ ++ +L P D + Y+K LG + + R TLNP++ Sbjct: 1550 PQECTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELS 1609 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQH--VARRLDHKLLNSQWYNLEKHVMVD 1417 P E+ L +SV D +D+ +G T+I L++ ++R H + ++ V Sbjct: 1610 CYLPQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEY--CVSGVNTW 1667 Query: 1418 GEQRKETKFSSRI------HLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGV---- 1567 +Q + T+ + I E G + YS D K L +H +G Sbjct: 1668 RDQLRPTQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQH-LGAPEER 1726 Query: 1568 LELGILTAQGLLP--MKTKDGRGTTDPYCVAKYGQKWV 1675 L L IL QGL+P ++T+ T P Q WV Sbjct: 1727 LALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWV 1764 Score = 39.3 bits (90), Expect = 0.10 Identities = 21/55 (38%), Positives = 26/55 (47%) Frame = +2 Query: 581 VEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQV 745 + QM + + VK + D DP+VEV K T EK NPEWNQV Sbjct: 370 IPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQV 424 Score = 36.6 bits (83), Expect = 0.65 Identities = 31/106 (29%), Positives = 55/106 (51%), Gaps = 7/106 (6%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMF-VAAEP- 1255 LRV ++E+ IP K P+ V + ++ +T+ LNP+WNE L F + P Sbjct: 2 LRV-IVESASNIPKTKFGKPDPIVSVIFKDEKKKTK-KVDNELNPVWNEILEFDLRGIPL 59 Query: 1256 -FEEHLILSVEDRIAPGKDDVIGRTVISLQHV----ARRLDHKLLN 1378 F L + V+D G++ +IG ++L+ + +R L +KL++ Sbjct: 60 DFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLIS 105 Score = 33.5 bits (75), Expect = 5.5 Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Frame = +2 Query: 575 DLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGN--YKGTTRHFEKKTNPEWNQVF 748 D V Q + + +V+ EL +D G CDPY+++ LG + + NP + +++ Sbjct: 1547 DSVPQECTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMY 1606 Query: 749 AFS 757 S Sbjct: 1607 ELS 1609
>Q4QQM1:PA24B_MOUSE Cytosolic phospholipase A2 beta - Mus musculus (Mouse)| Length = 1012 Score = 43.1 bits (100), Expect = 0.007 Identities = 26/59 (44%), Positives = 32/59 (54%), Gaps = 3/59 (5%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAFSKER 766 L VRV++A LPSKDL S D YV + L ++ TR + NP WNQ F F R Sbjct: 241 LTVRVLRASGLPSKDLVTSSDCYVTLNLPTASSHTLQTRTVKNSRNPVWNQNFHFRIHR 299
>Q69ZN7:MYOF_MOUSE Myoferlin - Mus musculus (Mouse)| Length = 2048 Score = 42.7 bits (99), Expect = 0.009 Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 9/97 (9%) Frame = +2 Query: 1073 LWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAE 1252 +++LR + +A++L+ DK F + Y +++ T + TLNP W++ ++F E Sbjct: 1125 IYHLRCYIYQARNLMALDKDSFSDPYAHVSFLHRSKTTEIIHS-TLNPTWDQTIIFDEVE 1183 Query: 1253 PFEE---------HLILSVEDRIAPGKDDVIGRTVIS 1336 F E ++ + + D GKD+ +GR++ S Sbjct: 1184 IFGEPQTVLQNPPNVTIELFDNDQVGKDEFLGRSICS 1220 Score = 39.3 bits (90), Expect = 0.10 Identities = 53/218 (24%), Positives = 88/218 (40%), Gaps = 15/218 (6%) Frame = +2 Query: 1067 PKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVS-PGRTLNPMWNEDLMFV 1243 P+ +R+ +++ L P D + Y+K LG + + R TLNP++ Sbjct: 1537 PQECTVRIYIVQGLQLQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELS 1596 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQH--VARRLDHKLLNSQWYNLEKHVMVD 1417 P E+ L +SV D +D+ +G T I L++ ++R H + Q+ V Sbjct: 1597 CYLPQEKDLKISVYDYDTFTRDEKVGETTIDLENRFLSRFGSHCGIPEQY--CVSGVNTW 1654 Query: 1418 GEQRKETKFSSRIHL------RICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGV---- 1567 +Q + T+ + + E G + Y D K L +H +G Sbjct: 1655 RDQLRPTQLLQNVARFKGFPPPVLSEDGSRIRYGGRDYHLDEFEANKILHQH-LGAPEER 1713 Query: 1568 LELGILTAQGLLP--MKTKDGRGTTDPYCVAKYGQKWV 1675 L L IL QGL+P ++T+ T P Q WV Sbjct: 1714 LALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWV 1751 Score = 38.1 bits (87), Expect = 0.22 Identities = 20/55 (36%), Positives = 26/55 (47%) Frame = +2 Query: 581 VEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQV 745 + QM + + VK + D DP+VEV K T E+ NPEWNQV Sbjct: 370 IPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIERNANPEWNQV 424 Score = 35.8 bits (81), Expect = 1.1 Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 3/90 (3%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMF-VAAEPF 1258 LRV ++E+ IP K P+ V + ++ +T+ LNP+WNE L F + P Sbjct: 2 LRV-IVESATNIPKTKFGKPDPIVSVIFKDEKKKTK-KVDNELNPVWNEILEFDLRGIPL 59 Query: 1259 E--EHLILSVEDRIAPGKDDVIGRTVISLQ 1342 + L++ V+D G++ +IG +SL+ Sbjct: 60 DSSSSLVIVVKDFETIGQNKLIGTATVSLK 89
>O75923:DYSF_HUMAN Dysferlin - Homo sapiens (Human)| Length = 2080 Score = 42.4 bits (98), Expect = 0.012 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%) Frame = +2 Query: 1076 WYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEP 1255 ++LR + +A+DL DK F + Y +Q+ +T V TLNP W++ L+F E Sbjct: 1152 YHLRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKN-TLNPTWDQTLIFYEIEI 1210 Query: 1256 FEE---------HLILSVEDRIAPGKDDVIGRTVI--SLQHVAR 1354 F E +++ + D G D+ +GR + SL+ + R Sbjct: 1211 FGEPATVAEQPPSIVVELYDHDTYGADEFMGRCICQPSLERMPR 1254 Score = 37.0 bits (84), Expect = 0.50 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = +2 Query: 1067 PKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSP-GRTLNPMWNEDLMFV 1243 P+ +R+ ++ A L P D + Y+K +G +++ + + TL P++ + Sbjct: 1575 PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELT 1634 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQH 1345 P E+ L +++ D KD+ IG TV+ L++ Sbjct: 1635 CTLPLEKDLKITLYDYDLLSKDEKIGETVVDLEN 1668 Score = 33.1 bits (74), Expect = 7.2 Identities = 13/35 (37%), Positives = 20/35 (57%) Frame = +2 Query: 1634 TDPYCVAKYGQKWVRTRTIIDSFTPKWNEQYTWEV 1738 +D YC A + RT+ I +S P WNE + W++ Sbjct: 20 SDAYCSAVFAGVKKRTKVIKNSVNPVWNEGFEWDL 54
>Q50L43:PA24D_MOUSE Cytosolic phospholipase A2 delta - Mus musculus (Mouse)| Length = 825 Score = 42.0 bits (97), Expect = 0.015 Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 3/55 (5%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGT---TRHFEKKTNPEWNQVFAF 754 L V++++A+ LP DL DPYV V+L G T+ ++P WN+ F+F Sbjct: 33 LTVKILEARSLPRADLLSQADPYVTVQLPTASGMKFKTQTVTNSSHPVWNETFSF 87
>Q5RBF2:NED4L_PONPY E3 ubiquitin-protein ligase NEDD4-like protein - Pongo pygmaeus| (Orangutan) Length = 959 Score = 42.0 bits (97), Expect = 0.015 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML------GNQALRTRVSPGRTLNPMWNEDLMFV 1243 LRV V+ DL D + YVK L AL + +TLNP WNE+ F Sbjct: 26 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYF- 84 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHV 1348 P L+ V D +DD +G+ + L H+ Sbjct: 85 RVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHL 119 Score = 39.3 bits (90), Expect = 0.10 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Frame = +2 Query: 1601 LPMKTKDGRGTTDPYC-----VAKYGQKW--VRTRTIIDSFTPKWNEQYTWEVHDPCTVI 1759 + + KD G +DPY VA ++ V+T+TI + PKWNE++ + V+ + Sbjct: 34 IDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRL 93 Query: 1760 TIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETD 1870 VFD L RD +G+V + LS L T+ Sbjct: 94 LFEVFDENRL--------TRDDFLGQVDVPLSHLPTE 122 Score = 38.1 bits (87), Expect = 0.22 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 9/65 (13%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKG---------TTRHFEKKTNPEWN 739 + + L V+VV +L KD+ G+ DPY VKL Y T+ +K NP+WN Sbjct: 22 ESRILRVKVVSGIDLAKKDIFGASDPY--VKLSLYVADENRELALVQTKTIKKTLNPKWN 79 Query: 740 QVFAF 754 + F F Sbjct: 80 EEFYF 84
>Q8CFI0:NED4L_MOUSE E3 ubiquitin-protein ligase NEDD4-like protein - Mus musculus (Mouse)| Length = 1004 Score = 42.0 bits (97), Expect = 0.015 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML------GNQALRTRVSPGRTLNPMWNEDLMFV 1243 LRV V+ DL D + YVK L AL + +TLNP WNE+ F Sbjct: 50 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYF- 108 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHV 1348 P L+ V D +DD +G+ + L H+ Sbjct: 109 RVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHL 143 Score = 39.3 bits (90), Expect = 0.10 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Frame = +2 Query: 1601 LPMKTKDGRGTTDPYC-----VAKYGQKW--VRTRTIIDSFTPKWNEQYTWEVHDPCTVI 1759 + + KD G +DPY VA ++ V+T+TI + PKWNE++ + V+ + Sbjct: 58 IDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRL 117 Query: 1760 TIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETD 1870 VFD L RD +G+V + LS L T+ Sbjct: 118 LFEVFDENRL--------TRDDFLGQVDVPLSHLPTE 146 Score = 38.1 bits (87), Expect = 0.22 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 9/65 (13%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKG---------TTRHFEKKTNPEWN 739 + + L V+VV +L KD+ G+ DPY VKL Y T+ +K NP+WN Sbjct: 46 ESRILRVKVVSGIDLAKKDIFGASDPY--VKLSLYVADENRELALVQTKTIKKTLNPKWN 103 Query: 740 QVFAF 754 + F F Sbjct: 104 EEFYF 108
>Q96PU5:NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like protein - Homo sapiens (Human)| Length = 975 Score = 42.0 bits (97), Expect = 0.015 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML------GNQALRTRVSPGRTLNPMWNEDLMFV 1243 LRV V+ DL D + YVK L AL + +TLNP WNE+ F Sbjct: 22 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYF- 80 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHV 1348 P L+ V D +DD +G+ + L H+ Sbjct: 81 RVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHL 115 Score = 39.3 bits (90), Expect = 0.10 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Frame = +2 Query: 1601 LPMKTKDGRGTTDPYC-----VAKYGQKW--VRTRTIIDSFTPKWNEQYTWEVHDPCTVI 1759 + + KD G +DPY VA ++ V+T+TI + PKWNE++ + V+ + Sbjct: 30 IDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRL 89 Query: 1760 TIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETD 1870 VFD L RD +G+V + LS L T+ Sbjct: 90 LFEVFDENRL--------TRDDFLGQVDVPLSHLPTE 118 Score = 38.1 bits (87), Expect = 0.22 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 9/65 (13%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKG---------TTRHFEKKTNPEWN 739 + + L V+VV +L KD+ G+ DPY VKL Y T+ +K NP+WN Sbjct: 18 ESRILRVKVVSGIDLAKKDIFGASDPY--VKLSLYVADENRELALVQTKTIKKTLNPKWN 75 Query: 740 QVFAF 754 + F F Sbjct: 76 EEFYF 80
>Q9QYX7:PCLO_MOUSE Protein piccolo - Mus musculus (Mouse)| Length = 5038 Score = 41.6 bits (96), Expect = 0.020 Identities = 33/139 (23%), Positives = 56/139 (40%), Gaps = 18/139 (12%) Frame = +2 Query: 557 KLTTTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL--------------GNYK 694 +L YDL L + +++A+ L +D G DP+V+V L YK Sbjct: 4597 QLQINYDLGN----LIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASVEYK 4652 Query: 695 GTTRHFEKKTNPEWNQVFAFS----KERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVP 862 T++ +K NPEWNQ + ++ ++ + G V+ DL+ Sbjct: 4653 RRTKYVQKSLNPEWNQTVIYKSISMEQLMKKTLEVTVWDYDRFSSNDFLGEVLIDLSST- 4711 Query: 863 KRVPPDSPLAPQWYRLEER 919 P+WY L+E+ Sbjct: 4712 ----SHLDNTPRWYPLKEQ 4726 Score = 32.7 bits (73), Expect = 9.4 Identities = 26/123 (21%), Positives = 58/123 (47%), Gaps = 16/123 (13%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML-------------GNQALRTRVSPGRTLNPMW 1222 L +++++A++L+P D + + +VK L + R ++LNP W Sbjct: 4607 LIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASVEYKRRTKYVQKSLNPEW 4666 Query: 1223 NEDLMFVA---AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYN 1393 N+ +++ + + ++ L ++V D +D +G +I L + LD+ +WY Sbjct: 4667 NQTVIYKSISMEQLMKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTS-HLDN---TPRWYP 4722 Query: 1394 LEK 1402 L++ Sbjct: 4723 LKE 4725
>P05696:KPCA_RAT Protein kinase C alpha type - Rattus norvegicus (Rat)| Length = 672 Score = 41.6 bits (96), Expect = 0.020 Identities = 37/125 (29%), Positives = 58/125 (46%), Gaps = 8/125 (6%) Frame = +2 Query: 1046 RSKVYLTPKLW--YLRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRT 1207 R ++YL ++ L V V +A++LIP D + YVK L N++ + + T Sbjct: 159 RGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRST 218 Query: 1208 LNPMWNEDLMFVAAEPFEEHLILSVE--DRIAPGKDDVIGRTVISLQHVARRLDHKLLNS 1381 LNP WNE F +P ++ LSVE D ++D +G + + K+ S Sbjct: 219 LNPQWNESFTF-KLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELM-----KMPAS 272 Query: 1382 QWYNL 1396 WY L Sbjct: 273 GWYKL 277 Score = 38.9 bits (89), Expect = 0.13 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 5/57 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF 754 L+V V AK L D G DPYV++KL K T+ NP+WN+ F F Sbjct: 173 LHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTF 229 Score = 35.4 bits (80), Expect = 1.5 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 5/62 (8%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYTW 1732 L + + A+ L+PM D G +DPY K + +T+TI + P+WNE +T+ Sbjct: 173 LHVTVRDAKNLIPM---DPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTF 229 Query: 1733 EV 1738 ++ Sbjct: 230 KL 231
>P10102:KPCA_RABIT Protein kinase C alpha type - Oryctolagus cuniculus (Rabbit)| Length = 672 Score = 41.6 bits (96), Expect = 0.020 Identities = 37/125 (29%), Positives = 58/125 (46%), Gaps = 8/125 (6%) Frame = +2 Query: 1046 RSKVYLTPKLW--YLRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRT 1207 R ++YL ++ L V V +A++LIP D + YVK L N++ + + T Sbjct: 159 RGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRST 218 Query: 1208 LNPMWNEDLMFVAAEPFEEHLILSVE--DRIAPGKDDVIGRTVISLQHVARRLDHKLLNS 1381 LNP WNE F +P ++ LSVE D ++D +G + + K+ S Sbjct: 219 LNPQWNESFTF-KLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELM-----KMPAS 272 Query: 1382 QWYNL 1396 WY L Sbjct: 273 GWYKL 277 Score = 38.9 bits (89), Expect = 0.13 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 5/57 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF 754 L+V V AK L D G DPYV++KL K T+ NP+WN+ F F Sbjct: 173 LHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTF 229 Score = 35.4 bits (80), Expect = 1.5 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 5/62 (8%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYTW 1732 L + + A+ L+PM D G +DPY K + +T+TI + P+WNE +T+ Sbjct: 173 LHVTVRDAKNLIPM---DPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTF 229 Query: 1733 EV 1738 ++ Sbjct: 230 KL 231
>Q7L804:RFIP2_HUMAN Rab11 family-interacting protein 2 - Homo sapiens (Human)| Length = 512 Score = 41.2 bits (95), Expect = 0.026 Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 9/130 (6%) Frame = +2 Query: 596 YLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQVFAFSKE--RI 769 ++ V V++AK+L K +G+ D Y ++LG K +T EK P W + +F I Sbjct: 14 HVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLI 73 Query: 770 QAS-----XXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHKV 934 Q S G+V +LN++ +W+RLE + G ++ Sbjct: 74 QGSPEKYILFLIVMHRSLVGLDKFLGQVAINLNDI---FEDKQRRKTEWFRLESKQGKRI 130 Query: 935 K--GELMLAV 958 K GE+ + + Sbjct: 131 KNRGEIKVNI 140
>P46934:NEDD4_HUMAN E3 ubiquitin-protein ligase NEDD4 - Homo sapiens (Human)| Length = 1000 Score = 41.2 bits (95), Expect = 0.026 Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 11/148 (7%) Frame = +2 Query: 1550 KHNIGVLELGILTAQGLLPMKTKDGRGTTDPYC-VAKYGQK-----WVRTRTIIDSFTPK 1711 + N ++ + ++ GL KD G +DPY V Y V+T+TI S PK Sbjct: 115 EENSRIVRVRVIAGIGLAK---KDILGASDPYVRVTLYDPMNGVLTSVQTKTIKKSLNPK 171 Query: 1712 WNEQYTWEVHDPCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLET-----DRV 1876 WNE+ + VH + VFD L RD +G+V + L L T +R Sbjct: 172 WNEEILFRVHPQQHRLLFEVFDENRL--------TRDDFLGQVDVPLYPLPTENPRLERP 223 Query: 1877 YTHSYPLIVLTPAGVKKMGEVQLAVRFT 1960 YT + VL P K + L ++ T Sbjct: 224 YT--FKDFVLHPRSHKSRVKGYLRLKMT 249 Score = 38.1 bits (87), Expect = 0.22 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 6/63 (9%) Frame = +2 Query: 584 EQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKG------TTRHFEKKTNPEWNQV 745 E + + VRV+ L KD+ G+ DPYV V L + T+ +K NP+WN+ Sbjct: 116 ENSRIVRVRVIAGIGLAKKDILGASDPYVRVTLYDPMNGVLTSVQTKTIKKSLNPKWNEE 175 Query: 746 FAF 754 F Sbjct: 176 ILF 178 Score = 34.7 bits (78), Expect = 2.5 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 6/92 (6%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQ------ALRTRVSPGRTLNPMWNEDLMFV 1243 +RV VI L D + YV+ L + +++T+ ++LNP WNE+++F Sbjct: 121 VRVRVIAGIGLAKKDILGASDPYVRVTLYDPMNGVLTSVQTKTIK-KSLNPKWNEEILF- 178 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISL 1339 P + L+ V D +DD +G+ + L Sbjct: 179 RVHPQQHRLLFEVFDENRLTRDDFLGQVDVPL 210
>P17252:KPCA_HUMAN Protein kinase C alpha type - Homo sapiens (Human)| Length = 672 Score = 41.2 bits (95), Expect = 0.026 Identities = 37/125 (29%), Positives = 58/125 (46%), Gaps = 8/125 (6%) Frame = +2 Query: 1046 RSKVYLTPKLW--YLRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRT 1207 R ++YL ++ L V V +A++LIP D + YVK L N++ + + T Sbjct: 159 RGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRST 218 Query: 1208 LNPMWNEDLMFVAAEPFEEHLILSVE--DRIAPGKDDVIGRTVISLQHVARRLDHKLLNS 1381 LNP WNE F +P ++ LSVE D ++D +G + + K+ S Sbjct: 219 LNPQWNESFTF-KLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELM-----KMPAS 272 Query: 1382 QWYNL 1396 WY L Sbjct: 273 GWYKL 277 Score = 38.9 bits (89), Expect = 0.13 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 5/57 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF 754 L+V V AK L D G DPYV++KL K T+ NP+WN+ F F Sbjct: 173 LHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTF 229 Score = 35.4 bits (80), Expect = 1.5 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 5/62 (8%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYTW 1732 L + + A+ L+PM D G +DPY K + +T+TI + P+WNE +T+ Sbjct: 173 LHVTVRDAKNLIPM---DPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTF 229 Query: 1733 EV 1738 ++ Sbjct: 230 KL 231
>Q9ESD7:DYSF_MOUSE Dysferlin - Mus musculus (Mouse)| Length = 2083 Score = 41.2 bits (95), Expect = 0.026 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%) Frame = +2 Query: 1076 WYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEP 1255 ++LR + +A+DL DK F + Y +Q+ +T V TLNP W++ L+F E Sbjct: 1155 YHLRCYLYQARDLPAMDKDSFSDPYSIVSFLHQSQKTVVEKN-TLNPTWDQTLIFYEIEI 1213 Query: 1256 FEEH---------LILSVEDRIAPGKDDVIGRTVI--SLQHVAR 1354 F E +++ + D G D+ +GR + SL+ + R Sbjct: 1214 FGEPASIAEHPPCIVVELYDHDTYGADEFMGRCICQPSLERMPR 1257 Score = 37.4 bits (85), Expect = 0.38 Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = +2 Query: 1067 PKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSP-GRTLNPMWNEDLMFV 1243 P+ +R+ ++ A L P D + Y+K +G +++ + + TL P++ + Sbjct: 1578 PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELT 1637 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQH 1345 P E+ L +++ D KD+ IG TVI L++ Sbjct: 1638 CTLPLEKDLKITLYDYDLLSKDEKIGETVIDLEN 1671
>P48231:TCB2_YEAST Tricalbin-2 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1178 Score = 40.8 bits (94), Expect = 0.035 Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 4/93 (4%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQA----LRTRVSPGRTLNPMWNEDLMFVAA 1249 L++ A++LI +K + + YV+ L ++ +T V +TLNP WNE + Sbjct: 985 LKITAKSAENLIGVNKNGYSDPYVEFFLNEKSTSPFFKTAVQK-KTLNPTWNESKTIEVS 1043 Query: 1250 EPFEEHLILSVEDRIAPGKDDVIGRTVISLQHV 1348 ++L ++V+D + + IG+ V+ L + Sbjct: 1044 NRVNDYLTINVKDYESTNSNRSIGKAVVPLSTI 1076 Score = 34.7 bits (78), Expect = 2.5 Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 5/120 (4%) Frame = +2 Query: 1556 NIGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQK----WVRTRTIIDSFTPKWNEQ 1723 N G L++ +A+ L+ + G +DPY +K + +T + P WNE Sbjct: 981 NSGDLKITAKSAENLIGVNKN---GYSDPYVEFFLNEKSTSPFFKTAVQKKTLNPTWNES 1037 Query: 1724 YTWEVHDPCT-VITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLI 1900 T EV + +TI V D E N R IGK + LST++ + T + PL+ Sbjct: 1038 KTIEVSNRVNDYLTINVKDY------ESTNSNRS--IGKAVVPLSTIDPESDTTFNIPLV 1089
>Q9JIR4:RIMS1_RAT Regulating synaptic membrane exocytosis protein 1 - Rattus norvegicus| (Rat) Length = 1615 Score = 40.0 bits (92), Expect = 0.059 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 15/130 (11%) Frame = +2 Query: 1061 LTPKLWY------LRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTL 1210 L+ KLWY L VNV++A DL P R YVK +++ R + + L Sbjct: 760 LSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKLL 819 Query: 1211 NPMWNEDLMF--VAAEPFEEHLI-LSVED--RIAPGKDDVIGRTVISLQHVARRLDHKLL 1375 P WN+ ++ V F E ++ ++V D R+ + + +G +I L+ LD + Sbjct: 820 EPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQDEESEFLGEILIELE--TALLDDE-- 875 Query: 1376 NSQWYNLEKH 1405 WY L+ H Sbjct: 876 -PHWYKLQTH 884
>Q99NE5:RIMS1_MOUSE Regulating synaptic membrane exocytosis protein 1 - Mus musculus| (Mouse) Length = 1463 Score = 40.0 bits (92), Expect = 0.059 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 15/130 (11%) Frame = +2 Query: 1061 LTPKLWY------LRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTL 1210 L+ KLWY L VNV++A DL P R YVK +++ R + + L Sbjct: 581 LSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKLL 640 Query: 1211 NPMWNEDLMF--VAAEPFEEHLI-LSVED--RIAPGKDDVIGRTVISLQHVARRLDHKLL 1375 P WN+ ++ V F E ++ ++V D R+ + + +G +I L+ LD + Sbjct: 641 EPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQDEESEFLGEILIELE--TALLDDE-- 696 Query: 1376 NSQWYNLEKH 1405 WY L+ H Sbjct: 697 -PHWYKLQTH 705
>Q12466:TCB1_YEAST Tricalbin-1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1186 Score = 39.7 bits (91), Expect = 0.077 Identities = 24/68 (35%), Positives = 37/68 (54%) Frame = +2 Query: 1205 TLNPMWNEDLMFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQ 1384 TLNP+W+E L +V F + L +SV D+ A KD V+GR +L + + + L +Q Sbjct: 431 TLNPVWDETL-YVLLNSFTDPLTISVYDKRAKLKDKVLGRIQYNLNTLHDKTTQRNLKAQ 489 Query: 1385 WYNLEKHV 1408 + K V Sbjct: 490 FLRNSKPV 497 Score = 39.3 bits (90), Expect = 0.10 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 3/85 (3%) Frame = +2 Query: 1103 AQDLIPNDKTRFPEVYVKAMLGNQ---ALRTRVSPGRTLNPMWNEDLMFVAAEPFEEHLI 1273 A++LI +D + + Y+K + N+ A +T+V +TLNP WN++ + L Sbjct: 1001 AENLIASDLNGYSDPYLKYYINNEEDCAYKTKVVK-KTLNPKWNDEGTIQINNRLNDVLR 1059 Query: 1274 LSVEDRIAPGKDDVIGRTVISLQHV 1348 + V D + DD IG I L V Sbjct: 1060 IKVMDWDSTSADDTIGTAEIPLNKV 1084 Score = 38.1 bits (87), Expect = 0.22 Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 1/135 (0%) Frame = +2 Query: 1556 NIGVLELGILTAQGLLPMKTKDGRGTTDPYCVAKYGQKWV-RTRTIIDSFTPKWNEQYTW 1732 +IG+LE+ + A+GL + + DPY ++ + +TRT+ D+ P W+E Sbjct: 384 SIGILEITVKNAKGLKRTSSILNE-SIDPYLSFEFNDISIAKTRTVRDTLNPVWDETLYV 442 Query: 1733 EVHDPCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHSYPLIVLTP 1912 ++ +TI V+D K +D +G+++ L+TL D+ + L Sbjct: 443 LLNSFTDPLTISVYD--------KRAKLKDKVLGRIQYNLNTLH-DKTTQRNLKAQFLRN 493 Query: 1913 AGVKKMGEVQLAVRF 1957 + K +GE+ +RF Sbjct: 494 S--KPVGELTFDLRF 506 Score = 38.1 bits (87), Expect = 0.22 Identities = 25/103 (24%), Positives = 50/103 (48%) Frame = +2 Query: 1049 SKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNE 1228 + V TP + +RV + +A DL +K + Y K ++ + +TLNP+WN+ Sbjct: 649 NSVAYTPPIGAIRVFIEKANDLRNLEKFGTIDPYCKVLVNGLSKGRTDFKSQTLNPVWNQ 708 Query: 1229 DLMFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARR 1357 +++VA + + L D KD +G +++Q + ++ Sbjct: 709 -VIYVAVTSPNQRITLQCMDVETVNKDRSLGEFNVNVQDLFKK 750 Score = 33.5 bits (75), Expect = 5.5 Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKL-GNYKGTTRHFEKKTNPEWNQV 745 V + KA +L + + G+ DPY +V + G KG T + NP WNQV Sbjct: 662 VFIEKANDLRNLEKFGTIDPYCKVLVNGLSKGRTDFKSQTLNPVWNQV 709 Score = 32.7 bits (73), Expect = 9.4 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 3/58 (5%) Frame = +2 Query: 575 DLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKG---TTRHFEKKTNPEWN 739 DL+ L + A+ L + DL G DPY++ + N + T+ +K NP+WN Sbjct: 986 DLITNSGDLTIMSRSAENLIASDLNGYSDPYLKYYINNEEDCAYKTKVVKKTLNPKWN 1043
>O95712:PA24B_HUMAN Cytosolic phospholipase A2 beta - Homo sapiens (Human)| Length = 1012 Score = 39.7 bits (91), Expect = 0.077 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 3/59 (5%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLG---NYKGTTRHFEKKTNPEWNQVFAFSKER 766 L VRV++A LPSKDL D YV + L +++ TR + ++P WNQ F F R Sbjct: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHR 301
>Q14184:DOC2B_HUMAN Double C2-like domain-containing protein beta - Homo sapiens (Human)| Length = 412 Score = 39.7 bits (91), Expect = 0.077 Identities = 61/234 (26%), Positives = 99/234 (42%), Gaps = 15/234 (6%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGR-TLNPMWNEDLMFVA- 1246 L + +A+ L P D + YVK L ++A + R R TLNP WNE L + Sbjct: 143 LHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGI 202 Query: 1247 --AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYN--LEKHVMV 1414 + + L +SV D ++ IG T + L+ + K +++ +N LEK + V Sbjct: 203 TDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKL------KPNHTKTFNICLEKQLPV 256 Query: 1415 DGEQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQ 1594 D + K + RI + S YSS + G+L +GI+ Sbjct: 257 DKTEDKSLEERGRILI-------------SLKYSSQKQ-----------GLL-VGIVRCA 291 Query: 1595 GLLPMKTKDGRGTTDPYCVAKYGQKWV------RTRTIIDSFTPKWNEQYTWEV 1738 L M D G +DPY V Y + V +T + P++NE++ +E+ Sbjct: 292 HLAAM---DANGYSDPY-VKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEI 341 Score = 33.5 bits (75), Expect = 5.5 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 5/61 (8%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFA 751 Q Q L V +V+ L + D G DPYV+ L K T +K NPE+N+ F Sbjct: 279 QKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFC 338 Query: 752 F 754 + Sbjct: 339 Y 339 Score = 32.7 bits (73), Expect = 9.4 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 5/57 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL--GNYKGT---TRHFEKKTNPEWNQVFAF 754 L+ + KAK L D G DPYV++ L G K T+ NP WN+ + Sbjct: 143 LHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTY 199
>P05126:KPCB_BOVIN Protein kinase C beta type - Bos taurus (Bovine)| Length = 673 Score = 39.3 bits (90), Expect = 0.10 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 5/61 (8%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFA 751 + + L V V AK L D G DPYV++KL K T+ + NPEWN+ F Sbjct: 169 EREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFR 228 Query: 752 F 754 F Sbjct: 229 F 229 Score = 33.1 bits (74), Expect = 7.2 Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Frame = +2 Query: 1565 VLELGILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYT 1729 VL + + A+ L+PM D G +DPY K + +T+TI S P+WNE + Sbjct: 172 VLIVVVRDAKNLVPM---DPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFR 228 Query: 1730 WEVHD 1744 +++ + Sbjct: 229 FQLKE 233
>P20444:KPCA_MOUSE Protein kinase C alpha type - Mus musculus (Mouse)| Length = 672 Score = 39.3 bits (90), Expect = 0.10 Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 8/134 (5%) Frame = +2 Query: 1046 RSKVYLTPKLW--YLRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRT 1207 R ++YL ++ L V V +A++LIP D + YVK L N++ + + Sbjct: 159 RGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSN 218 Query: 1208 LNPMWNEDLMFVAAEPFEEHLILSVE--DRIAPGKDDVIGRTVISLQHVARRLDHKLLNS 1381 LNP WNE F +P ++ LSVE D ++D +G + + K+ S Sbjct: 219 LNPQWNESFTF-KLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELM-----KMPAS 272 Query: 1382 QWYNLEKHVMVDGE 1423 WY + H +GE Sbjct: 273 GWY--KAHNQEEGE 284 Score = 39.3 bits (90), Expect = 0.10 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 5/57 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF 754 L+V V AK L D G DPYV++KL K T+ NP+WN+ F F Sbjct: 173 LHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSNLNPQWNESFTF 229 Score = 35.4 bits (80), Expect = 1.5 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 5/62 (8%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYTW 1732 L + + A+ L+PM D G +DPY K + +T+TI + P+WNE +T+ Sbjct: 173 LHVTVRDAKNLIPM---DPNGLSDPYVKLKLIPDPKNESKQKTKTIRSNLNPQWNESFTF 229 Query: 1733 EV 1738 ++ Sbjct: 230 KL 231
>P68403:KPCB_RAT Protein kinase C beta type - Rattus norvegicus (Rat)| Length = 671 Score = 38.9 bits (89), Expect = 0.13 Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 5/59 (8%) Frame = +2 Query: 593 QYLYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF 754 + L V V AK L D G DPYV++KL K T+ + NPEWN+ F F Sbjct: 171 EVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRF 229 Score = 33.1 bits (74), Expect = 7.2 Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Frame = +2 Query: 1565 VLELGILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYT 1729 VL + + A+ L+PM D G +DPY K + +T+TI S P+WNE + Sbjct: 172 VLIVVVRDAKNLVPM---DPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFR 228 Query: 1730 WEVHD 1744 +++ + Sbjct: 229 FQLKE 233
>P05772:KPCB_RABIT Protein kinase C beta type - Oryctolagus cuniculus (Rabbit)| Length = 671 Score = 38.9 bits (89), Expect = 0.13 Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 5/59 (8%) Frame = +2 Query: 593 QYLYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF 754 + L V V AK L D G DPYV++KL K T+ + NPEWN+ F F Sbjct: 171 EVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRF 229 Score = 33.1 bits (74), Expect = 7.2 Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Frame = +2 Query: 1565 VLELGILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYT 1729 VL + + A+ L+PM D G +DPY K + +T+TI S P+WNE + Sbjct: 172 VLIVVVRDAKNLVPM---DPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFR 228 Query: 1730 WEVHD 1744 +++ + Sbjct: 229 FQLKE 233
>P68404:KPCB_MOUSE Protein kinase C beta type - Mus musculus (Mouse)| Length = 673 Score = 38.9 bits (89), Expect = 0.13 Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 5/59 (8%) Frame = +2 Query: 593 QYLYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF 754 + L V V AK L D G DPYV++KL K T+ + NPEWN+ F F Sbjct: 171 EVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRF 229 Score = 33.1 bits (74), Expect = 7.2 Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Frame = +2 Query: 1565 VLELGILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYT 1729 VL + + A+ L+PM D G +DPY K + +T+TI S P+WNE + Sbjct: 172 VLIVVVRDAKNLVPM---DPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFR 228 Query: 1730 WEVHD 1744 +++ + Sbjct: 229 FQLKE 233
>P05771:KPCB_HUMAN Protein kinase C beta type - Homo sapiens (Human)| Length = 671 Score = 38.9 bits (89), Expect = 0.13 Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 5/57 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF 754 L V V AK L D G DPYV++KL K T+ + NPEWN+ F F Sbjct: 173 LIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRF 229 Score = 32.7 bits (73), Expect = 9.4 Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Frame = +2 Query: 1565 VLELGILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYT 1729 VL + + A+ L+PM D G +DPY K + +T+TI S P+WNE + Sbjct: 172 VLIVLVRDAKNLVPM---DPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFR 228 Query: 1730 WEVHD 1744 +++ + Sbjct: 229 FQLKE 233
>P50232:SYT4_RAT Synaptotagmin-4 - Rattus norvegicus (Rat)| Length = 425 Score = 38.5 bits (88), Expect = 0.17 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 7/59 (11%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKT-------NPEWNQVFAF 754 L V V+KA+ LP D++G DPYV+V L Y R +KKT N +N++F F Sbjct: 304 LTVVVLKARHLPKSDVSGLSDPYVKVNL--YHAKKRISKKKTHVKKCTPNAVFNELFVF 360
>P40749:SYT4_MOUSE Synaptotagmin-4 - Mus musculus (Mouse)| Length = 425 Score = 38.5 bits (88), Expect = 0.17 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 7/59 (11%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKT-------NPEWNQVFAF 754 L V V+KA+ LP D++G DPYV+V L Y R +KKT N +N++F F Sbjct: 304 LTVVVLKARHLPKSDVSGLSDPYVKVNL--YHAKKRISKKKTHVKKCTPNAVFNELFVF 360
>Q9H2B2:SYT4_HUMAN Synaptotagmin-4 - Homo sapiens (Human)| Length = 425 Score = 38.5 bits (88), Expect = 0.17 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 7/59 (11%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKT-------NPEWNQVFAF 754 L V V+KA+ LP D++G DPYV+V L Y R +KKT N +N++F F Sbjct: 304 LTVVVLKARHLPKSDVSGLSDPYVKVNL--YHAKKRISKKKTHVKKCTPNAVFNELFVF 360
>Q06846:RP3A_BOVIN Rabphilin-3A - Bos taurus (Bovine)| Length = 704 Score = 38.5 bits (88), Expect = 0.17 Identities = 68/329 (20%), Positives = 113/329 (34%), Gaps = 21/329 (6%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF--- 754 L+ ++KAK L D G DPYV++ L + K T+ NP WN+ + Sbjct: 419 LHCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGI 478 Query: 755 -SKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHK 931 ++ + + G F L K++ P+ + +N + Sbjct: 479 TDEDMQRKTLRISVCDEDKFGHNEFIGETRFSL----KKLKPN----------QRKNFNI 524 Query: 932 VKGELMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWY------LRVN 1093 ++ GT + + GD I + + L Y L V Sbjct: 525 CLERVIPMKRAGTTGSARGMALYEEEQVERIGD----IEERGKILVSLMYSTQQGGLIVG 580 Query: 1094 VIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTLNPMWNEDLMF--VAAEP 1255 +I L D + + +VK L G +A +TLNP +NE+ + ++ Sbjct: 581 IIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDL 640 Query: 1256 FEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQRKE 1435 ++ L +SV D +D IG + + RL H WY K+ K+ Sbjct: 641 AKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKH------WYECLKN--------KD 686 Query: 1436 TKFSSRIHLRICLEGGYHVLDESTHYSSD 1522 K +H L H SSD Sbjct: 687 KKIER-----------WHQLQNENHVSSD 704
>P10895:PLCD1_BOVIN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 -| Bos taurus (Bovine) Length = 695 Score = 38.5 bits (88), Expect = 0.17 Identities = 36/108 (33%), Positives = 51/108 (47%), Gaps = 7/108 (6%) Frame = +2 Query: 1064 TPKLWYLRVNVIEAQDLIPNDKTRF----PEVYVK--AMLGNQALR-TRVSPGRTLNPMW 1222 TPK L V VI Q L +K + P+V V+ + G+ A R T V NP W Sbjct: 566 TPKR--LNVRVISGQQLPKVNKNKNSIVDPKVTVEIHGVTGDVASRQTAVVTNNGFNPWW 623 Query: 1223 NEDLMFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDH 1366 + +L F A P + VED A K+D IG++ I L+ + + H Sbjct: 624 DTELEFEVAVPELALVRFVVEDYDASSKNDFIGQSTIPLKSLKQGYRH 671
>P63319:KPCG_RAT Protein kinase C gamma type - Rattus norvegicus (Rat)| Length = 697 Score = 38.5 bits (88), Expect = 0.17 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 11/116 (9%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTLNPMWNEDLMF-VA 1246 + + V EA++LIP D + YVK L N + + TLNP+WNE +F + Sbjct: 173 IHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFNLK 232 Query: 1247 AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARR-LD--HKLLN---SQWYNL 1396 E L + V D ++D +G + + + +D +KLLN ++YN+ Sbjct: 233 PGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNV 288 Score = 35.4 bits (80), Expect = 1.5 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAFS 757 +++ V +A+ L D G DPYV++KL K T+ + NP WN+ F F+ Sbjct: 173 IHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFN 230
>P10829:KPCG_RABIT Protein kinase C gamma type - Oryctolagus cuniculus (Rabbit)| Length = 697 Score = 38.5 bits (88), Expect = 0.17 Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 11/116 (9%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTLNPMWNEDLMF-VA 1246 + V V EA++LIP D + YVK L N + + TLNP+WNE +F + Sbjct: 173 IHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLK 232 Query: 1247 AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARR-LD--HKLLN---SQWYNL 1396 E L + V D ++D +G + + + +D +KLLN ++YN+ Sbjct: 233 PGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNV 288 Score = 37.0 bits (84), Expect = 0.50 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAFS 757 ++V V +A+ L D G DPYV++KL K TR + NP WN+ F F+ Sbjct: 173 IHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFN 230
>P63318:KPCG_MOUSE Protein kinase C gamma type - Mus musculus (Mouse)| Length = 697 Score = 38.5 bits (88), Expect = 0.17 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 11/116 (9%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTLNPMWNEDLMF-VA 1246 + + V EA++LIP D + YVK L N + + TLNP+WNE +F + Sbjct: 173 IHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFNLK 232 Query: 1247 AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARR-LD--HKLLN---SQWYNL 1396 E L + V D ++D +G + + + +D +KLLN ++YN+ Sbjct: 233 PGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNV 288 Score = 35.4 bits (80), Expect = 1.5 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAFS 757 +++ V +A+ L D G DPYV++KL K T+ + NP WN+ F F+ Sbjct: 173 IHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFN 230
>P05129:KPCG_HUMAN Protein kinase C gamma type - Homo sapiens (Human)| Length = 697 Score = 38.5 bits (88), Expect = 0.17 Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 11/116 (9%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTLNPMWNEDLMF-VA 1246 + V V EA++LIP D + YVK L N + + TLNP+WNE +F + Sbjct: 173 IHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLK 232 Query: 1247 AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARR-LD--HKLLN---SQWYNL 1396 E L + V D ++D +G + + + +D +KLLN ++YN+ Sbjct: 233 PGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNV 288 Score = 37.0 bits (84), Expect = 0.50 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAFS 757 ++V V +A+ L D G DPYV++KL K TR + NP WN+ F F+ Sbjct: 173 IHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFN 230
>P05128:KPCG_BOVIN Protein kinase C gamma type - Bos taurus (Bovine)| Length = 682 Score = 38.5 bits (88), Expect = 0.17 Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 11/116 (9%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTLNPMWNEDLMF-VA 1246 + V V EA++LIP D + YVK L N + + TLNP+WNE +F + Sbjct: 158 IHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLK 217 Query: 1247 AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARR-LD--HKLLN---SQWYNL 1396 E L + V D ++D +G + + + +D +KLLN ++YN+ Sbjct: 218 PGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNV 273 Score = 37.0 bits (84), Expect = 0.50 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAFS 757 ++V V +A+ L D G DPYV++KL K TR + NP WN+ F F+ Sbjct: 158 IHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFN 215
>P90980:KPC2_CAEEL Protein kinase C-like 2 - Caenorhabditis elegans| Length = 682 Score = 38.5 bits (88), Expect = 0.17 Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 12/132 (9%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML-----GNQALRTRVSPGRTLNPMWNEDLMF-V 1243 L + ++EA++LIP D + YVK L G ++ + + TLNP WNE + + Sbjct: 175 LTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTYKL 234 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLD---HKLLNS---QWYNLEKH 1405 + L + V D ++D +G + + + +KLL++ ++YN+ Sbjct: 235 LPGDKDRRLSIEVWDWDRTSRNDFMGSLSFGISELMKEAASGWYKLLSAEEGEFYNINIT 294 Query: 1406 VMVDGEQRKETK 1441 D + K K Sbjct: 295 PEYDEDMEKVRK 306 Score = 37.0 bits (84), Expect = 0.50 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL------GNYKGTTRHFEKKTNPEWNQVFAF 754 L +++++AK L D G DPYV+ KL K T+ NP+WN+ F + Sbjct: 175 LTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTY 232 Score = 35.0 bits (79), Expect = 1.9 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 6/63 (9%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKY------GQKWVRTRTIIDSFTPKWNEQYT 1729 L + IL A+ L+PM D G +DPY K + +T+T+ + P+WNE +T Sbjct: 175 LTIKILEAKNLIPM---DPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFT 231 Query: 1730 WEV 1738 +++ Sbjct: 232 YKL 234
>Q4R4U2:KPCG_MACFA Protein kinase C gamma type - Macaca fascicularis (Crab eating| macaque) (Cynomolgus monkey) Length = 697 Score = 38.1 bits (87), Expect = 0.22 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 11/116 (9%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTLNPMWNEDLMF-VA 1246 + + V EA++LIP D + YVK L N + + TLNP+WNE +F + Sbjct: 173 IHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLK 232 Query: 1247 AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARR-LD--HKLLN---SQWYNL 1396 E L + V D ++D +G + + + +D +KLLN ++YN+ Sbjct: 233 PGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNV 288 Score = 36.6 bits (83), Expect = 0.65 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAFS 757 +++ V +A+ L D G DPYV++KL K TR + NP WN+ F F+ Sbjct: 173 IHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFN 230
>P05130:KPC1_DROME Protein kinase C, brain isozyme - Drosophila melanogaster (Fruit fly)| Length = 679 Score = 38.1 bits (87), Expect = 0.22 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 7/110 (6%) Frame = +2 Query: 1046 RSKVYL--TPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRT 1207 R ++YL K L V + E ++LIP D + YVK L +Q+ + + Sbjct: 177 RGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKKKTRTIKAC 236 Query: 1208 LNPMWNEDLMF-VAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVAR 1354 LNP+WNE L + + E + +++ V D ++D +G + + + Sbjct: 237 LNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEIIK 286 Score = 35.8 bits (81), Expect = 1.1 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%) Frame = +2 Query: 515 KETTPHLGGAAAGDKLTTTY-DLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL--- 682 KE P L G ++ Y ++ + L V++ + + L D G DPYV+VKL Sbjct: 162 KENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPD 221 Query: 683 --GNYKGTTRHFEKKTNPEWNQVFAF 754 K TR + NP WN+ + Sbjct: 222 DKDQSKKKTRTIKACLNPVWNETLTY 247 Score = 33.5 bits (75), Expect = 5.5 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 15/87 (17%) Frame = +2 Query: 1562 GVLELGILTAQGLLPMKTKDGR--------GTTDPYCVAKY-----GQKWVRTRTIIDSF 1702 G + L I + LL ++ K+GR G +DPY K Q +TRTI Sbjct: 178 GRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKKKTRTIKACL 237 Query: 1703 TPKWNEQYTWEV--HDPCTVITIGVFD 1777 P WNE T+++ D I I V+D Sbjct: 238 NPVWNETLTYDLKPEDKDRRILIEVWD 264
>P70610:DOC2B_RAT Double C2-like domain-containing protein beta - Rattus norvegicus| (Rat) Length = 412 Score = 38.1 bits (87), Expect = 0.22 Identities = 60/232 (25%), Positives = 95/232 (40%), Gaps = 13/232 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGR-TLNPMWNEDLMFVA- 1246 L + +A+ L P D + YVK L ++A + R R TLNP WNE L + Sbjct: 143 LHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGI 202 Query: 1247 --AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 + + L +SV D ++ IG T + L ++L + LEK + VD Sbjct: 203 TDEDMIRKTLRISVCDEDKFRHNEFIGETRVPL----KKLKPNHTKTFSICLEKQLPVDK 258 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 + K + RI + S YSS + G+L +GI+ L Sbjct: 259 AEDKSLEERGRILI-------------SLKYSSQKQ-----------GLL-VGIVRCAHL 293 Query: 1601 LPMKTKDGRGTTDPYCVAKYGQKWV------RTRTIIDSFTPKWNEQYTWEV 1738 M D G +DPY V Y + V +T + P++NE++ +E+ Sbjct: 294 AAM---DANGYSDPY-VKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEI 341 Score = 33.5 bits (75), Expect = 5.5 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 5/61 (8%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFA 751 Q Q L V +V+ L + D G DPYV+ L K T +K NPE+N+ F Sbjct: 279 QKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFC 338 Query: 752 F 754 + Sbjct: 339 Y 339
>Q9UT00:YKH3_SCHPO Uncharacterized protein PYUK71.03c - Schizosaccharomyces pombe| (Fission yeast) Length = 1225 Score = 37.7 bits (86), Expect = 0.29 Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Frame = +2 Query: 575 DLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL-GNYKGTTRHFEKKTNPEWNQVF 748 ++ E M + V V+KA +LP+ D G DP+V +L G T+ ++ NP +N+ F Sbjct: 1031 EMYENMGEMTVDVIKATDLPAADSNGKSDPFVVFELQGEEVYRTKTHKRTLNPTFNESF 1089
>Q9C8S6:Y1322_ARATH C2 domain-containing protein At1g63220 - Arabidopsis thaliana| (Mouse-ear cress) Length = 147 Score = 37.7 bits (86), Expect = 0.29 Identities = 25/89 (28%), Positives = 40/89 (44%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFE 1261 L V ++ A+ L D + YV+ Q ++ V+ G P WNE +F +E Sbjct: 6 LEVVLVSAKGLEDADFLNNMDPYVQLTCRTQDQKSNVAEGMGTTPEWNETFIFTVSEGTT 65 Query: 1262 EHLILSVEDRIAPGKDDVIGRTVISLQHV 1348 E L + D+ +DD +G I L+ V Sbjct: 66 E-LKAKIFDKDVGTEDDAVGEATIPLEPV 93 Score = 33.1 bits (74), Expect = 7.2 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFE-KKTNPEWNQVFAFS 757 L V +V AK L D + DPYV++ + E T PEWN+ F F+ Sbjct: 6 LEVVLVSAKGLEDADFLNNMDPYVQLTCRTQDQKSNVAEGMGTTPEWNETFIFT 59
>Q9Y2J0:RP3A_HUMAN Rabphilin-3A - Homo sapiens (Human)| Length = 694 Score = 37.7 bits (86), Expect = 0.29 Identities = 68/329 (20%), Positives = 112/329 (34%), Gaps = 21/329 (6%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF--- 754 L ++KAK L D G DPYV++ L + K T+ NP WN+ + Sbjct: 409 LQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGI 468 Query: 755 -SKERIQASXXXXXXXXXXXXXXXXXGRVMFDLNEVPKRVPPDSPLAPQWYRLEERNGHK 931 ++ + + G F L K++ P+ + +N + Sbjct: 469 TDEDMQRKTLRISVCDEDKFGHNEFIGETRFSL----KKLKPN----------QRKNFNI 514 Query: 932 VKGELMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWY------LRVN 1093 ++ GT + + GD I + + L Y L V Sbjct: 515 CLERVIPMKRAGTTGSARGMALYEEEQVERVGD----IEERGKILVSLMYSTQQGGLIVG 570 Query: 1094 VIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRTLNPMWNEDLMF--VAAEP 1255 +I L D + + +VK L G +A +TLNP +NE+ + ++ Sbjct: 571 IIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDL 630 Query: 1256 FEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQRKE 1435 ++ L +SV D +D IG + + RL H WY K+ K+ Sbjct: 631 AKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKH------WYECLKN--------KD 676 Query: 1436 TKFSSRIHLRICLEGGYHVLDESTHYSSD 1522 K +H L H SSD Sbjct: 677 KKIER-----------WHQLQNENHVSSD 694 Score = 32.7 bits (73), Expect = 9.4 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 11/86 (12%) Frame = +2 Query: 1496 DESTHYSSDLRPTA-----KQLWKHNIGVLELGILTAQGLLPMKTKDGRGTTDPYCV--- 1651 +E+ Y SD T L+ + L+ I+ A+GL PM D G DPY Sbjct: 380 EEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPM---DSNGLADPYVKLHL 436 Query: 1652 ---AKYGQKWVRTRTIIDSFTPKWNE 1720 A K +RT+T+ ++ P WNE Sbjct: 437 LPGASKSNK-LRTKTLRNTRNPIWNE 461
>P70169:DOC2B_MOUSE Double C2-like domain-containing protein beta - Mus musculus (Mouse)| Length = 412 Score = 37.7 bits (86), Expect = 0.29 Identities = 60/232 (25%), Positives = 95/232 (40%), Gaps = 13/232 (5%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAML---GNQALRTRVSPGR-TLNPMWNEDLMFVA- 1246 L + +A+ L P D + YVK L ++A + R R TLNP WNE L + Sbjct: 143 LHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGI 202 Query: 1247 --AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDG 1420 + + L +SV D ++ IG T + L ++L + LEK + VD Sbjct: 203 TDEDMVRKTLRISVCDEDKFRHNEFIGETRVPL----KKLKPNHTKTFSICLEKQLPVDK 258 Query: 1421 EQRKETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQLWKHNIGVLELGILTAQGL 1600 + K + RI + S YSS + G+L +GI+ L Sbjct: 259 AEDKSLEERGRILI-------------SLKYSSQKQ-----------GLL-VGIVRCAHL 293 Query: 1601 LPMKTKDGRGTTDPYCVAKYGQKWV------RTRTIIDSFTPKWNEQYTWEV 1738 M D G +DPY V Y + V +T + P++NE++ +E+ Sbjct: 294 AAM---DANGYSDPY-VKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEI 341 Score = 33.5 bits (75), Expect = 5.5 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 5/61 (8%) Frame = +2 Query: 587 QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFA 751 Q Q L V +V+ L + D G DPYV+ L K T +K NPE+N+ F Sbjct: 279 QKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFC 338 Query: 752 F 754 + Sbjct: 339 Y 339
>Q92462:PUB1_SCHPO E3 ubiquitin-protein ligase pub1 - Schizosaccharomyces pombe (Fission| yeast) Length = 767 Score = 37.4 bits (85), Expect = 0.38 Identities = 16/49 (32%), Positives = 25/49 (51%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNE 1228 +RV ++ A L D RFP+ + + + T + +TLNP WNE Sbjct: 10 IRVTIVAADGLYKRDVFRFPDPFAVLTVDGEQTHTTTAIKKTLNPYWNE 58
>Q9ZT47:PP16A_CUCMA 16 kDa phloem protein 1 - Cucurbita maxima (Pumpkin) (Winter squash)| Length = 150 Score = 37.4 bits (85), Expect = 0.38 Identities = 32/152 (21%), Positives = 62/152 (40%), Gaps = 4/152 (2%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFP-EVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEP- 1255 + V++I + L +D P + Y + Q ++V+ NP+W+E F+A P Sbjct: 6 MEVHLISGKGLQAHDPLNKPIDPYAEINFKGQERMSKVAKNAGPNPLWDEKFKFLAEYPG 65 Query: 1256 --FEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQR 1429 + H++ V D A DD IG I + K+++ +G ++ Sbjct: 66 SGGDFHILFKVMDHDAIDGDDYIGDVKIDV--------------------KNLLAEGVRK 105 Query: 1430 KETKFSSRIHLRICLEGGYHVLDESTHYSSDL 1525 +++ R+ YHVL H+ ++ Sbjct: 106 GKSEMPPRM---------YHVLAHKIHFKGEI 128
>P46935:NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4 - Mus musculus (Mouse)| Length = 887 Score = 37.4 bits (85), Expect = 0.38 Identities = 44/151 (29%), Positives = 63/151 (41%), Gaps = 11/151 (7%) Frame = +2 Query: 1541 QLWKHNIGVLELGILTAQGLLPMKTKDGRGTTDPYC-VAKYGQKW-----VRTRTIIDSF 1702 +L + V+ + ++ GL KD G +DPY V Y V+T+TI S Sbjct: 71 ELHNDDTRVVRVKVIAGIGLAK---KDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSL 127 Query: 1703 TPKWNEQYTWEVHDPCTVITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLET----- 1867 PKWNE+ + V I VFD L RD +G+V + L L T Sbjct: 128 NPKWNEEILFRVLPQRHRILFEVFDENRL--------TRDDFLGQVDVPLYPLPTENPRM 179 Query: 1868 DRVYTHSYPLIVLTPAGVKKMGEVQLAVRFT 1960 +R YT + VL P K + L ++ T Sbjct: 180 ERPYT--FKDFVLHPRSHKSRVKGYLRLKMT 208 Score = 35.8 bits (81), Expect = 1.1 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 6/56 (10%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKG------TTRHFEKKTNPEWNQVFAF 754 V+V+ L KD+ G+ DPYV V L + T+ +K NP+WN+ F Sbjct: 82 VKVIAGIGLAKKDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSLNPKWNEEILF 137
>Q16974:KPC1_APLCA Calcium-dependent protein kinase C - Aplysia californica| (California sea hare) Length = 649 Score = 37.4 bits (85), Expect = 0.38 Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 5/53 (9%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNY-----KGTTRHFEKKTNPEWNQVF 748 V +++AK L D G DPYV+VKL Y K T+ + NP WN+ F Sbjct: 159 VEILEAKNLCPMDPNGLADPYVKVKLIPYDAHKLKLKTKTIKASLNPVWNESF 211 Score = 34.3 bits (77), Expect = 3.2 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 6/84 (7%) Frame = +2 Query: 1088 VNVIEAQDLIPNDKTRFPEVYVKAML-----GNQALRTRVSPGRTLNPMWNEDL-MFVAA 1249 V ++EA++L P D + YVK L L+T+ +LNP+WNE + + Sbjct: 159 VEILEAKNLCPMDPNGLADPYVKVKLIPYDAHKLKLKTKTIKA-SLNPVWNESFTVDIGP 217 Query: 1250 EPFEEHLILSVEDRIAPGKDDVIG 1321 E + L L V D ++D +G Sbjct: 218 EDNSKRLSLEVWDWDRTSRNDFMG 241 Score = 33.9 bits (76), Expect = 4.2 Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 5/58 (8%) Frame = +2 Query: 1580 ILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYTWEV 1738 IL A+ L PM D G DPY K + ++T+TI S P WNE +T ++ Sbjct: 161 ILEAKNLCPM---DPNGLADPYVKVKLIPYDAHKLKLKTKTIKASLNPVWNESFTVDI 215
>Q28BX9:K0528_XENTR Uncharacterized protein KIAA0528 homolog - Xenopus tropicalis| (Western clawed frog) (Silurana tropicalis) Length = 1014 Score = 37.4 bits (85), Expect = 0.38 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSC-DPYVEVKLGNYKGTTRHFEKKTNPEWN 739 L V++V + LP D D +VEVK GN T + K NP+WN Sbjct: 5 LKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYHKSLNPQWN 52
>Q86XP0:PA24D_HUMAN Cytosolic phospholipase A2 delta - Homo sapiens (Human)| Length = 818 Score = 37.0 bits (84), Expect = 0.50 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKG---TTRHFEKKTNPEWNQVFAF 754 L VRV++A+ L DL DPYV ++L G T+ ++P WN+ F F Sbjct: 24 LTVRVLEARNLRWADLLSEADPYVILQLSTAPGMKFKTKTLTDTSHPVWNEAFRF 78 Score = 34.7 bits (78), Expect = 2.5 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 3/94 (3%) Frame = +2 Query: 1076 WYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGN---QALRTRVSPGRTLNPMWNEDLMFVA 1246 W L V V+EA++L D + YV L +T+ T +P+WNE F+ Sbjct: 22 WQLTVRVLEARNLRWADLLSEADPYVILQLSTAPGMKFKTKTLTD-TSHPVWNEAFRFLI 80 Query: 1247 AEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHV 1348 + L LS+ D + +DD+ + + + V Sbjct: 81 QSQVKNVLELSIYDEDSVTEDDICFKVLYDISEV 114
>Q62940:NEDD4_RAT E3 ubiquitin-protein ligase NEDD4 - Rattus norvegicus (Rat)| Length = 887 Score = 37.0 bits (84), Expect = 0.50 Identities = 40/126 (31%), Positives = 53/126 (42%), Gaps = 11/126 (8%) Frame = +2 Query: 1616 KDGRGTTDPYC-VAKYGQKW-----VRTRTIIDSFTPKWNEQYTWEVHDPCTVITIGVFD 1777 KD G +DPY V Y V+T+TI S PKWNE+ + V I VFD Sbjct: 90 KDILGASDPYVRVTLYDPMSGVLTSVQTKTIKKSLNPKWNEEILFRVLPQQHRILFEVFD 149 Query: 1778 NCHLNGGEKANGARDTRIGKVRIRLSTLET-----DRVYTHSYPLIVLTPAGVKKMGEVQ 1942 L RD +G+V + L L T +R YT + VL P K + Sbjct: 150 ENRL--------TRDDFLGQVDVPLYPLPTENPRMERPYT--FKDFVLHPRSHKSRVKGY 199 Query: 1943 LAVRFT 1960 L ++ T Sbjct: 200 LRLKMT 205 Score = 35.8 bits (81), Expect = 1.1 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 6/56 (10%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKG------TTRHFEKKTNPEWNQVFAF 754 V+V+ L KD+ G+ DPYV V L + T+ +K NP+WN+ F Sbjct: 79 VKVIAGIGLAKKDILGASDPYVRVTLYDPMSGVLTSVQTKTIKKSLNPKWNEEILF 134 Score = 32.7 bits (73), Expect = 9.4 Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 6/92 (6%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQ------ALRTRVSPGRTLNPMWNEDLMFV 1243 +RV VI L D + YV+ L + +++T+ ++LNP WNE+++F Sbjct: 77 VRVKVIAGIGLAKKDILGASDPYVRVTLYDPMSGVLTSVQTKTIK-KSLNPKWNEEILF- 134 Query: 1244 AAEPFEEHLILSVEDRIAPGKDDVIGRTVISL 1339 P + ++ V D +DD +G+ + L Sbjct: 135 RVLPQQHRILFEVFDENRLTRDDFLGQVDVPL 166
>P04409:KPCA_BOVIN Protein kinase C alpha type - Bos taurus (Bovine)| Length = 672 Score = 37.0 bits (84), Expect = 0.50 Identities = 35/125 (28%), Positives = 57/125 (45%), Gaps = 8/125 (6%) Frame = +2 Query: 1046 RSKVYLTPKLW--YLRVNVIEAQDLIPNDKTRFPEVYVKAML----GNQALRTRVSPGRT 1207 R ++YL ++ L V V +A++LIP D + YVK L N++ + + T Sbjct: 159 RGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRST 218 Query: 1208 LNPMWNEDLMFVAAEPFEEHLILSVE--DRIAPGKDDVIGRTVISLQHVARRLDHKLLNS 1381 LNP W+E F +P ++ LS E D ++D +G + + K+ S Sbjct: 219 LNPRWDESFTF-KLKPSDKDRRLSEEIWDWDRTTRNDFMGSLSFGVSELM-----KMPAS 272 Query: 1382 QWYNL 1396 WY L Sbjct: 273 GWYKL 277 Score = 36.2 bits (82), Expect = 0.85 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 5/57 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAF 754 L+V V AK L D G DPYV++KL K T+ NP W++ F F Sbjct: 173 LHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWDESFTF 229 Score = 33.9 bits (76), Expect = 4.2 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 5/62 (8%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPYCVAKY-----GQKWVRTRTIIDSFTPKWNEQYTW 1732 L + + A+ L+PM D G +DPY K + +T+TI + P+W+E +T+ Sbjct: 173 LHVTVRDAKNLIPM---DPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWDESFTF 229 Query: 1733 EV 1738 ++ Sbjct: 230 KL 231
>Q8IYJ3:SYTL1_HUMAN Synaptotagmin-like protein 1 - Homo sapiens (Human)| Length = 562 Score = 36.6 bits (83), Expect = 0.65 Identities = 37/117 (31%), Positives = 55/117 (47%), Gaps = 9/117 (7%) Frame = +2 Query: 1016 SIPGDGLA-----SIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAML--GNQ 1174 S+ GD A S+ ++ P LRV+VI+ Q L + R + YVK+ L Q Sbjct: 256 SLSGDAEAVQVRGSVHFALHYEPGAAELRVHVIQCQGLAAARRRR-SDPYVKSYLLPDKQ 314 Query: 1175 ALRTRVSPGRTLNPMWNEDLMFVA--AEPFEEHLILSVEDRIAPGKDDVIGRTVISL 1339 + R R LNP++NE L + AE L LSV R + G++ +G + L Sbjct: 315 SKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVWHRESLGRNIFLGEVEVPL 371
>P47709:RP3A_RAT Rabphilin-3A - Rattus norvegicus (Rat)| Length = 684 Score = 36.6 bits (83), Expect = 0.65 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 7/94 (7%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTL----NPMWNEDLMF--V 1243 L+ +I A+ L P D + YVK L A ++ +TL NP+WNE L + + Sbjct: 399 LQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGI 458 Query: 1244 AAEPFE-EHLILSVEDRIAPGKDDVIGRTVISLQ 1342 E + + L +SV D G ++ IG T SL+ Sbjct: 459 TEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLK 492 Score = 33.1 bits (74), Expect = 7.2 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 11/86 (12%) Frame = +2 Query: 1496 DESTHYSSDLRPTA-----KQLWKHNIGVLELGILTAQGLLPMKTKDGRGTTDPYCV--- 1651 +E+ Y SD T L+ + L+ I+ A+GL PM D G DPY Sbjct: 370 EEANSYDSDQATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPM---DSNGLADPYVKLHL 426 Query: 1652 ---AKYGQKWVRTRTIIDSFTPKWNE 1720 A K +RT+T+ ++ P WNE Sbjct: 427 LPGASKSNK-LRTKTLRNTRNPVWNE 451
>P47708:RP3A_MOUSE Rabphilin-3A - Mus musculus (Mouse)| Length = 681 Score = 36.6 bits (83), Expect = 0.65 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 7/94 (7%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTL----NPMWNEDLMF--V 1243 L+ +I A+ L P D + YVK L A ++ +TL NP+WNE L + + Sbjct: 396 LQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGI 455 Query: 1244 AAEPFE-EHLILSVEDRIAPGKDDVIGRTVISLQ 1342 E + + L +SV D G ++ IG T SL+ Sbjct: 456 TEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLK 489 Score = 32.7 bits (73), Expect = 9.4 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 11/86 (12%) Frame = +2 Query: 1496 DESTHYSSDLRPTA-----KQLWKHNIGVLELGILTAQGLLPMKTKDGRGTTDPYCV--- 1651 +E+ Y SD T L+ + L+ I+ A+GL PM D G DPY Sbjct: 367 EEANSYDSDEATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPM---DSNGLADPYVKLHL 423 Query: 1652 ---AKYGQKWVRTRTIIDSFTPKWNE 1720 A K +RT+T+ ++ P WNE Sbjct: 424 LPGASKSNK-LRTKTLRNTRNPVWNE 448
>O77793:PA24A_HORSE Cytosolic phospholipase A2 - Equus caballus (Horse)| Length = 749 Score = 36.6 bits (83), Expect = 0.65 Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGT---TRHFEKKTNPEWNQVFAF 754 +R K + D+ + DPYVE+ + + + TRHF NP WN+ F F Sbjct: 25 LRATKVTKGAFGDMLDTPDPYVELFISSTPDSRKRTRHFNNNINPVWNETFEF 77
>P13677:KPC2_DROME Protein kinase C, eye isozyme - Drosophila melanogaster (Fruit fly)| Length = 700 Score = 36.6 bits (83), Expect = 0.65 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Frame = +2 Query: 506 YSLKETTPHLGGAAAGDKLTTTYDLVE-QMQYLYVRVVKAKELPSKDLTGSCDPYVEVKL 682 ++ +ET P + GA + VE + L V + +A L D G DPY+ V++ Sbjct: 176 HACQETVPPMCGADISEVRGKLLLYVELKGNNLKVDIKEAANLIPMDTNGFSDPYIAVQM 235 Query: 683 -----GNYKGTTRHFEKKTNPEWNQVFAF 754 G K T+ +K NP +N+ F F Sbjct: 236 HPDRSGRTKKKTKTIQKNLNPVFNETFTF 264
>Q03640:TCB3_YEAST Tricalbin-3 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1545 Score = 36.2 bits (82), Expect = 0.85 Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Frame = +2 Query: 581 VEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKT-NPEWNQ 742 VE YL ++++ L S D G DP+V + + + K + +KKT +P WN+ Sbjct: 1130 VEDTGYLNIKLISGHGLKSADRNGYSDPFVHIFVNDKKVFKSNIKKKTLDPVWNE 1184 Score = 36.2 bits (82), Expect = 0.85 Identities = 19/87 (21%), Positives = 40/87 (45%) Frame = +2 Query: 1079 YLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPF 1258 YL + +I L D+ + + +V + ++ + +TL+P+WNED Sbjct: 1135 YLNIKLISGHGLKSADRNGYSDPFVHIFVNDKKVFKSNIKKKTLDPVWNEDAKIPILSRS 1194 Query: 1259 EEHLILSVEDRIAPGKDDVIGRTVISL 1339 + +I +V D G +D +G+ + + Sbjct: 1195 KNQVIFNVLDWDRAGDNDDLGQASLDV 1221
>Q9NYJ8:TAB2_HUMAN Mitogen-activated protein kinase kinase kinase 7-interacting| protein 2 - Homo sapiens (Human) Length = 693 Score = 36.2 bits (82), Expect = 0.85 Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 7/119 (5%) Frame = -1 Query: 746 TPGSTQDWSSFQNAELCPYNSRASPQHTGHNFQ*GPYLEVPSLLPLEHKGTASAQPGHRW 567 TPG T + + + +N +PQ Q GP+ P+ PL H T+S QP + Sbjct: 221 TPGGTTRQTQQHSGWVSQFNPM-NPQQVYQPSQPGPWTTCPASNPLSH--TSSQQPNQQG 277 Query: 566 W*ACHLQLPHQGEE*SPSRSTPP----GGMASASS*MTVLNQTIPTQGRKGR---KIQP 411 H+ +P SP+ S PP G + +S+ Q I T RK + K++P Sbjct: 278 HQTSHVYMPIS----SPTTSQPPTIHSSGSSQSSAHSQYNIQNISTGPRKNQIEIKLEP 332
>P39940:RSP5_YEAST E3 ubiquitin-protein ligase RSP5 - Saccharomyces cerevisiae| (Baker's yeast) Length = 809 Score = 36.2 bits (82), Expect = 0.85 Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKT-NPEWNQVFAF 754 V++V A+ L +D+ S DP+ + + Y+ + KKT NP WN+ F F Sbjct: 7 VKLVAAESLYKRDVFRSPDPFAVLTIDGYQTKSTSAAKKTLNPYWNETFKF 57 Score = 34.3 bits (77), Expect = 3.2 Identities = 17/68 (25%), Positives = 33/68 (48%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVSPGRTLNPMWNEDLMFVAAEPFE 1261 + V ++ A+ L D R P+ + + ++ + +TLNP WNE F + Sbjct: 5 ISVKLVAAESLYKRDVFRSPDPFAVLTIDGYQTKSTSAAKKTLNPYWNETFKF---DDIN 61 Query: 1262 EHLILSVE 1285 E+ IL+++ Sbjct: 62 ENSILTIQ 69
>Q9JIS1:RIMS2_RAT Regulating synaptic membrane exocytosis protein 2 - Rattus| norvegicus (Rat) Length = 1555 Score = 36.2 bits (82), Expect = 0.85 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEV-----KLGNYKGTTRHFEKKTNPEWNQVFAFS 757 L V ++ AK+LPS++ +PYV++ + K T+ +K P+WNQ F +S Sbjct: 760 LIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYS 817
>Q9EQZ7:RIMS2_MOUSE Regulating synaptic membrane exocytosis protein 2 - Mus musculus| (Mouse) Length = 1530 Score = 36.2 bits (82), Expect = 0.85 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEV-----KLGNYKGTTRHFEKKTNPEWNQVFAFS 757 L V ++ AK+LPS++ +PYV++ + K T+ +K P+WNQ F +S Sbjct: 831 LIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYS 888
>Q9UQ26:RIMS2_HUMAN Regulating synaptic membrane exocytosis protein 2 - Homo sapiens| (Human) Length = 1411 Score = 36.2 bits (82), Expect = 0.85 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEV-----KLGNYKGTTRHFEKKTNPEWNQVFAFS 757 L V ++ AK+LPS++ +PYV++ + K T+ +K P+WNQ F +S Sbjct: 822 LIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYS 879
>O04883:PLDA1_PIMBR Phospholipase D alpha 1 - Pimpinella brachycarpa| Length = 808 Score = 36.2 bits (82), Expect = 0.85 Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Frame = +2 Query: 1139 PEVYVKAMLGNQAL-RTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAPGKDDV 1315 P++Y L + RTR+ NP WNE P ++I +V+D D+ Sbjct: 47 PKIYASIDLDKARVGRTRMIENEPNNPKWNESFHIYCGHP-STNVIFTVKD------DNP 99 Query: 1316 IGRTVISLQHVARRLDHKLLNSQWYNLEKHVMVDGEQRKETKFSSRIHLRI 1468 IG T+I ++ H+LL + ++K V + E + S+IH+++ Sbjct: 100 IGATLIGRAYLP---VHELLEGE--EVDKWVEILDEDKNPISEGSKIHVKL 145
>P50393:PA24A_RAT Cytosolic phospholipase A2 - Rattus norvegicus (Rat)| Length = 752 Score = 36.2 bits (82), Expect = 0.85 Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLG---NYKGTTRHFEKKTNPEWNQVFAF 754 +R K + D+ + DPYVE+ + + + TRHF NP WN+ F F Sbjct: 25 LRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEF 77
>P47713:PA24A_MOUSE Cytosolic phospholipase A2 - Mus musculus (Mouse)| Length = 748 Score = 36.2 bits (82), Expect = 0.85 Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLG---NYKGTTRHFEKKTNPEWNQVFAF 754 +R K + D+ + DPYVE+ + + + TRHF NP WN+ F F Sbjct: 25 LRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEF 77
>P47712:PA24A_HUMAN Cytosolic phospholipase A2 - Homo sapiens (Human)| Length = 749 Score = 36.2 bits (82), Expect = 0.85 Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Frame = +2 Query: 605 VRVVKAKELPSKDLTGSCDPYVEVKLG---NYKGTTRHFEKKTNPEWNQVFAF 754 +R K + D+ + DPYVE+ + + + TRHF NP WN+ F F Sbjct: 25 LRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEF 77
>Q5RDC8:K0528_PONPY Uncharacterized protein KIAA0528 homolog - Pongo pygmaeus| (Orangutan) Length = 1000 Score = 36.2 bits (82), Expect = 0.85 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSC-DPYVEVKLGNYKGTTRHFEKKTNPEWN 739 L V++V + LP D D +VEVK GN T + K NP+WN Sbjct: 5 LKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWN 52
>Q7TPS5:K0528_MOUSE Uncharacterized protein KIAA0528 - Mus musculus (Mouse)| Length = 1016 Score = 36.2 bits (82), Expect = 0.85 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSC-DPYVEVKLGNYKGTTRHFEKKTNPEWN 739 L V++V + LP D D +VEVK GN T + K NP+WN Sbjct: 5 LKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWN 52
>Q86YS7:K0528_HUMAN Uncharacterized protein KIAA0528 - Homo sapiens (Human)| Length = 1000 Score = 36.2 bits (82), Expect = 0.85 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSC-DPYVEVKLGNYKGTTRHFEKKTNPEWN 739 L V++V + LP D D +VEVK GN T + K NP+WN Sbjct: 5 LKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWN 52
>Q17388:FER1_CAEEL Sperm vesicle fusion protein fer-1 - Caenorhabditis elegans| Length = 2034 Score = 36.2 bits (82), Expect = 0.85 Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 1/97 (1%) Frame = +2 Query: 1058 YLTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQALRTRVS-PGRTLNPMWNEDL 1234 ++ P +RV +IEA LI N + + YVK G Q + + + +P++ E + Sbjct: 1377 FVGPTRCLVRVYIIEANGLISNARKGRVDSYVKLHCGKQNVNLKKNYRSECCDPIFGERV 1436 Query: 1235 MFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQH 1345 P E+ L ++V + D IG T I L++ Sbjct: 1437 DMTVTIPLEKDLKITVMGKRRILSDQEIGSTTIDLEN 1473
>P50392:PA24A_DANRE Cytosolic phospholipase A2 - Danio rerio (Zebrafish) (Brachydanio| rerio) Length = 741 Score = 35.8 bits (81), Expect = 1.1 Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 9/69 (13%) Frame = +2 Query: 575 DLVEQMQY---LYVRVVKAKELPSK---DLTGSCDPYVEVKLGNY---KGTTRHFEKKTN 727 +++ + QY L + VV+A+ + DL + DPYVE+ + + TRH N Sbjct: 3 NIIVEHQYSHRLKLTVVRAENVTKGAFGDLLDTPDPYVELSVPTTPESRKRTRHINNDIN 62 Query: 728 PEWNQVFAF 754 P+WN+ F F Sbjct: 63 PKWNETFEF 71
>Q25378:KPC1_LYTPI Protein kinase C - Lytechinus pictus (Painted sea urchin)| Length = 658 Score = 35.8 bits (81), Expect = 1.1 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 5/60 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-----GNYKGTTRHFEKKTNPEWNQVFAFSKE 763 L V V +AK L D G DP+V++KL K TR + NP W + F F+ E Sbjct: 164 LQVTVAEAKNLIPMDPNGLSDPFVKLKLIPDQKRETKKKTRTIKGSLNPTWGESFDFNLE 223
>Q8R5Z2:TIG_FUSNN Trigger factor - Fusobacterium nucleatum subsp. nucleatum| Length = 429 Score = 35.4 bits (80), Expect = 1.5 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Frame = +2 Query: 497 PEEYSLKETTPHLGGAAAGDKLTTTY-DLVEQMQYLYVRVVKAKELPSKD---LTGSCDP 664 P+E + H+ A D + + ++V++ + V V+ KE+ KD LT D Sbjct: 50 PKEVLMTNYKDHIESDVANDAINANFPEIVDKEKLEPVSYVRLKEINLKDDLNLTFDIDV 109 Query: 665 YVEVKLGNYKG 697 Y + +LGNYKG Sbjct: 110 YPQFELGNYKG 120
>Q8K4S1:PLCE1_MOUSE 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon 1 -| Mus musculus (Mouse) Length = 2282 Score = 35.4 bits (80), Expect = 1.5 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 3/63 (4%) Frame = +2 Query: 1061 LTPKLWYLRVNVIEAQDLIPNDKTRFPEVYVKAM---LGNQALRTRVSPGRTLNPMWNED 1231 L P ++ L +I Q++ P++ T P + V + L + RT+ TLNPMWNE Sbjct: 1846 LDPAIYSL--TIISGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQ 1903 Query: 1232 LMF 1240 +F Sbjct: 1904 FLF 1906
>P47861:SYT5_RAT Synaptotagmin-5 - Rattus norvegicus (Rat)| Length = 386 Score = 35.0 bits (79), Expect = 1.9 Identities = 46/203 (22%), Positives = 90/203 (44%), Gaps = 27/203 (13%) Frame = +2 Query: 1430 KETKFSSRIHLRICLEGGYHVLDESTHYSSDLRPTAKQ-----LWKHNIGVLE------- 1573 K+++ +++HL+ E G +D+ +L P+ L KH +G L+ Sbjct: 61 KKSQAQAQVHLQEVKELGRSYIDKVQPEIEELDPSPSMPGQQVLDKHQLGRLQYSLDYDF 120 Query: 1574 ------LGILTAQGLLPMKTKDGRGTTDPYCVAKY----GQKWVRTRTIIDSFTPKWNEQ 1723 +GIL A+GL + D G++DPY V+ Y ++ T+ + P + E Sbjct: 121 QTGQLLVGILQAEGLAAL---DLGGSSDPY-VSVYLLPDKRRRHETKVHRQTLNPHFGET 176 Query: 1724 YTWEVHDPCT-----VITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHS 1888 + ++V P V+ + V+D + R+ IG+VR+ +S++ R Sbjct: 177 FAFKV--PYVELGGRVLVMAVYDFDRFS--------RNDAIGEVRVPMSSVNLGRPVQAW 226 Query: 1889 YPLIVLTPAGVKKMGEVQLAVRF 1957 L V +K+G++ ++R+ Sbjct: 227 RELQVAPKEEQEKLGDICFSLRY 249 Score = 34.7 bits (78), Expect = 2.5 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 7/59 (11%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKT-------NPEWNQVFAF 754 L V V++AK L D+ G DPYV+V L +G + +KKT NP +N+ F+F Sbjct: 256 LTVIVLEAKNLKKMDVGGLSDPYVKVHL--LQGGKKVRKKKTTIKKNTLNPYYNEAFSF 312
>Q99P84:PLCE1_RAT 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon 1 -| Rattus norvegicus (Rat) Length = 2281 Score = 35.0 bits (79), Expect = 1.9 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 3/54 (5%) Frame = +2 Query: 1088 VNVIEAQDLIPNDKTRFPEVYVKAM---LGNQALRTRVSPGRTLNPMWNEDLMF 1240 + +I Q++ P++ T P + V + L + RT+ TLNPMWNE +F Sbjct: 1852 LTIISGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLF 1905
>P49147:PA24A_CHICK Cytosolic phospholipase A2 - Gallus gallus (Chicken)| Length = 748 Score = 35.0 bits (79), Expect = 1.9 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 9/68 (13%) Frame = +2 Query: 578 LVEQMQYLYVRVVKAKELPSK------DLTGSCDPYVEVKLGNY---KGTTRHFEKKTNP 730 +V + QY +V V ++ + D+ + DPYVE+ + + + T+HF NP Sbjct: 10 IVVEHQYSHVFTVTVRKATNVTKGAIGDMLDTPDPYVELFIPSAPDCRKRTKHFNNDVNP 69 Query: 731 EWNQVFAF 754 WN+ F F Sbjct: 70 VWNETFEF 77
>Q9R0N5:SYT5_MOUSE Synaptotagmin-5 - Mus musculus (Mouse)| Length = 386 Score = 34.7 bits (78), Expect = 2.5 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 7/59 (11%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKT-------NPEWNQVFAF 754 L V V++AK L D+ G DPYV+V L +G + +KKT NP +N+ F+F Sbjct: 256 LTVIVLEAKNLKKMDVGGLSDPYVKVHL--LQGGKKVRKKKTTIKKNTLNPYYNEAFSF 312 Score = 32.7 bits (73), Expect = 9.4 Identities = 46/203 (22%), Positives = 89/203 (43%), Gaps = 27/203 (13%) Frame = +2 Query: 1430 KETKFSSRIHLRICLEGGYHVLDESTHYSSDL-----RPTAKQLWKHNIGVLE------- 1573 K+++ +++HL+ E G +D+ +L P + KH +G L+ Sbjct: 61 KKSQAQAQVHLQEVKELGRSYIDKVQPEIEELDRSPSMPGQQVSDKHQLGRLQYSLDYDF 120 Query: 1574 ------LGILTAQGLLPMKTKDGRGTTDPYCVAKY----GQKWVRTRTIIDSFTPKWNEQ 1723 +GIL AQGL + D G++DPY V+ Y ++ T+ + P + E Sbjct: 121 QTGQLLVGILQAQGLAAL---DLGGSSDPY-VSVYLLPDKRRRHETKVHRQTLNPHFGET 176 Query: 1724 YTWEVHDPCT-----VITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLETDRVYTHS 1888 + ++V P V+ + V+D + R+ IG+VR+ +S++ R Sbjct: 177 FAFKV--PYVELGGRVLVMAVYDFDRFS--------RNDAIGEVRVPMSSVNLGRPVQAW 226 Query: 1889 YPLIVLTPAGVKKMGEVQLAVRF 1957 L V +K+G++ ++R+ Sbjct: 227 RELQVAPKEEQEKLGDICFSLRY 249
>O00445:SYT5_HUMAN Synaptotagmin-5 - Homo sapiens (Human)| Length = 386 Score = 34.7 bits (78), Expect = 2.5 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 7/59 (11%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKT-------NPEWNQVFAF 754 L V V++AK L D+ G DPYV+V L +G + +KKT NP +N+ F+F Sbjct: 256 LTVIVLEAKNLKKMDVGGLSDPYVKVHL--LQGGKKVRKKKTTIKKNTLNPYYNEAFSF 312
>P70611:DOC2A_RAT Double C2-like domain-containing protein alpha - Rattus norvegicus| (Rat) Length = 403 Score = 34.7 bits (78), Expect = 2.5 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL--GNYKGT---TRHFEKKTNPEWNQVFAFS 757 L+ R+++AK L D G DPYV++ L G K T+ NP WN+ +S Sbjct: 109 LHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYS 166 Score = 33.9 bits (76), Expect = 4.2 Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 13/113 (11%) Frame = +2 Query: 1565 VLELGILTAQGLLPMKTKDGRGTTDPY---------CVAKYGQKWVRTRTIIDSFTPKWN 1717 +L IL A+GL PM D G DPY C A ++T+T ++ P WN Sbjct: 108 MLHCRILRAKGLKPM---DFNGLADPYVKLHLLPGACKANK----LKTKTQRNTLNPVWN 160 Query: 1718 EQYTWE--VHDPCT--VITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLE 1864 E+ T+ D T V+ I V D L+ E IG++R+ L L+ Sbjct: 161 EELTYSGITDDDITHKVLRISVCDEDKLSHNE--------FIGEIRVPLRRLK 205
>Q7TNF0:DOC2A_MOUSE Double C2-like domain-containing protein alpha - Mus musculus| (Mouse) Length = 405 Score = 34.7 bits (78), Expect = 2.5 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 5/58 (8%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL--GNYKGT---TRHFEKKTNPEWNQVFAFS 757 L+ R+++AK L D G DPYV++ L G K T+ NP WN+ +S Sbjct: 111 LHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYS 168 Score = 33.9 bits (76), Expect = 4.2 Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 13/113 (11%) Frame = +2 Query: 1565 VLELGILTAQGLLPMKTKDGRGTTDPY---------CVAKYGQKWVRTRTIIDSFTPKWN 1717 +L IL A+GL PM D G DPY C A ++T+T ++ P WN Sbjct: 110 MLHCRILRAKGLKPM---DFNGLADPYVKLHLLPGACKANK----LKTKTQRNTLNPVWN 162 Query: 1718 EQYTWE--VHDPCT--VITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLE 1864 E+ T+ D T V+ I V D L+ E IG++R+ L L+ Sbjct: 163 EELTYSGITDDDITHKVLRISVCDEDKLSHNE--------FIGEIRVPLRRLK 207
>Q9USG8:MU190_SCHPO Meiotically up-regulated gene 190 protein - Schizosaccharomyces pombe| (Fission yeast) Length = 1188 Score = 34.3 bits (77), Expect = 3.2 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 8/92 (8%) Frame = +2 Query: 1088 VNVIEAQDLIPNDKTRFPEVYVKA---MLGNQALRTRVSPGRTLNPMWNEDLMF-VAAEP 1255 V++ A+DL D + Y+ G TRV + LNP+WNE V + Sbjct: 473 VHINRAEDLSKQDVNGLSDAYITVGFHKFGKPLYCTRVVK-QDLNPIWNEYAFIPVFPDQ 531 Query: 1256 FEEHLILSVE----DRIAPGKDDVIGRTVISL 1339 + +S+E DR +P DDV+GRT I L Sbjct: 532 VKAGEKISIELWDSDRFSP--DDVVGRTKIGL 561
>Q5RAT8:IF38_PONPY Eukaryotic translation initiation factor 3 subunit 8 - Pongo pygmaeus| (Orangutan) Length = 913 Score = 34.3 bits (77), Expect = 3.2 Identities = 27/94 (28%), Positives = 36/94 (38%), Gaps = 9/94 (9%) Frame = -2 Query: 2362 QSGIGEEDCRQYQLRIQDQYHKEDMDQYSRQWVPPVTDLIKPSSNCNQRAQDTHD-TEEV 2186 + G EE CR Y LRI Y+K D + RQ PP +D+ E + Sbjct: 492 EKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERL 551 Query: 2185 C---LALSHAPHVR-----IHIQHVLHNFFSQWW 2108 C A +R HI H H S+W+ Sbjct: 552 CKYIYAKDRTDRIRTCAILCHIYH--HALHSRWY 583
>Q99613:IF38_HUMAN Eukaryotic translation initiation factor 3 subunit 8 - Homo sapiens| (Human) Length = 913 Score = 34.3 bits (77), Expect = 3.2 Identities = 27/94 (28%), Positives = 36/94 (38%), Gaps = 9/94 (9%) Frame = -2 Query: 2362 QSGIGEEDCRQYQLRIQDQYHKEDMDQYSRQWVPPVTDLIKPSSNCNQRAQDTHD-TEEV 2186 + G EE CR Y LRI Y+K D + RQ PP +D+ E + Sbjct: 492 EKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERL 551 Query: 2185 C---LALSHAPHVR-----IHIQHVLHNFFSQWW 2108 C A +R HI H H S+W+ Sbjct: 552 CKYIYAKDRTDRIRTCAILCHIYH--HALHSRWY 583
>Q70J99:UN13D_HUMAN Unc-13 homolog D - Homo sapiens (Human)| Length = 1090 Score = 33.9 bits (76), Expect = 4.2 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 10/99 (10%) Frame = +2 Query: 1082 LRVNVIEAQDLIPNDKTRFPEVYVKAMLGNQ------ALRTRVSPGRTLNPMWNEDLMF- 1240 LRV ++ A L+P D + +V+ L + A R + L+P+++E F Sbjct: 927 LRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEFL 986 Query: 1241 VAAEPFEEH---LILSVEDRIAPGKDDVIGRTVISLQHV 1348 V AEP + L+L+V D G DD+ G + L+ V Sbjct: 987 VPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREV 1025
>Q8R3B1:PLCD1_MOUSE 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 -| Mus musculus (Mouse) Length = 756 Score = 33.9 bits (76), Expect = 4.2 Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 11/119 (9%) Frame = +2 Query: 1061 LTPKLWY----LRVNVIEAQDLIPNDKTRF----PEVYVKAMLGNQALRTR---VSPGRT 1207 LT W+ LRV +I Q L +K + P+V V+ Q + +R V Sbjct: 620 LTQGPWWAPKKLRVWIISGQQLPKVNKNKNSIVDPKVIVEIHGVGQDVASRQTAVITNNG 679 Query: 1208 LNPMWNEDLMFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQHVARRLDHKLLNSQ 1384 NP W+ + FV A P + VED + K+D IG++ I + + H L S+ Sbjct: 680 FNPRWDTEFEFVVAVPDLALVRFMVEDYDSSSKNDFIGQSTIPWNSLKQGYRHVHLLSK 738
>O04865:PLDA1_VIGUN Phospholipase D alpha 1 - Vigna unguiculata (Cowpea)| Length = 809 Score = 33.5 bits (75), Expect = 5.5 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 2/98 (2%) Frame = +2 Query: 1181 RTRVSPGRTLNPMWNEDLMFVAAEPFEEHLILSVEDRIAPGKDDVIGRTVISLQH--VAR 1354 RTR+ T NP WNE ++I +V+D D+ IG T+I + V+ Sbjct: 62 RTRIIENETTNPKWNESFHIYCGH-LASNIIFTVKD------DNPIGATLIGRAYVPVSE 114 Query: 1355 RLDHKLLNSQWYNLEKHVMVDGEQRKETKFSSRIHLRI 1468 LD + ++K V + ++ + S+IH+R+ Sbjct: 115 VLD-------GHEIDKWVEILDTEKNPIEGGSKIHVRL 145
>Q14183:DOC2A_HUMAN Double C2-like domain-containing protein alpha - Homo sapiens (Human)| Length = 400 Score = 33.5 bits (75), Expect = 5.5 Identities = 35/112 (31%), Positives = 48/112 (42%), Gaps = 13/112 (11%) Frame = +2 Query: 1568 LELGILTAQGLLPMKTKDGRGTTDPY---------CVAKYGQKWVRTRTIIDSFTPKWNE 1720 L IL A+GL PM D G DPY C A ++T+T ++ P WNE Sbjct: 106 LHCSILRAKGLKPM---DFNGLADPYVKLHLLPGACKANK----LKTKTQRNTLNPVWNE 158 Query: 1721 QYTWE--VHDPCT--VITIGVFDNCHLNGGEKANGARDTRIGKVRIRLSTLE 1864 T+ D T V+ I V D L+ E IG++R+ L L+ Sbjct: 159 DLTYSGITDDDITHKVLRIAVCDEDKLSHNE--------FIGEIRVPLRRLK 202 Score = 32.7 bits (73), Expect = 9.4 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 5/96 (5%) Frame = +2 Query: 968 TQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEAQDLIPNDKTRFPEV 1147 T D A +++ SD A+ L ++ + L +++ A+ L P D + Sbjct: 72 TPEDGAEVDSYDSDDAT----ALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADP 127 Query: 1148 YVKAMLGNQA-----LRTRVSPGRTLNPMWNEDLMF 1240 YVK L A L+T+ TLNP+WNEDL + Sbjct: 128 YVKLHLLPGACKANKLKTKTQRN-TLNPVWNEDLTY 162
>Q14644:RASA3_HUMAN Ras GTPase-activating protein 3 - Homo sapiens (Human)| Length = 834 Score = 33.1 bits (74), Expect = 7.2 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 4/60 (6%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL-GNYKG---TTRHFEKKTNPEWNQVFAFSKER 766 L R+V+ + LP + G CDPY V L G ++ T+ K NP++++VF F R Sbjct: 147 LATRIVECQGLPI--VNGQCDPYATVTLAGPFRSEAKKTKVKRKTNNPQFDEVFYFEVTR 204
>P50904:RASA1_RAT Ras GTPase-activating protein 1 - Rattus norvegicus (Rat)| Length = 1038 Score = 33.1 bits (74), Expect = 7.2 Identities = 17/63 (26%), Positives = 31/63 (49%) Frame = +2 Query: 566 TTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQV 745 T+ + Q+ L + + +A +LP K T +PY + L + + H + NP W++ Sbjct: 576 TSNKRLRQVSSLVLHIEEAHKLPVKHFT---NPYCNIYLNSVQVAKTHAREGQNPVWSEE 632 Query: 746 FAF 754 F F Sbjct: 633 FVF 635
>P20936:RASA1_HUMAN Ras GTPase-activating protein 1 - Homo sapiens (Human)| Length = 1047 Score = 33.1 bits (74), Expect = 7.2 Identities = 17/63 (26%), Positives = 31/63 (49%) Frame = +2 Query: 566 TTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQV 745 T+ + Q+ L + + +A +LP K T +PY + L + + H + NP W++ Sbjct: 585 TSNKRLRQVSSLVLHIEEAHKLPVKHFT---NPYCNIYLNSVQVAKTHAREGQNPVWSEE 641 Query: 746 FAF 754 F F Sbjct: 642 FVF 644
>P09851:RASA1_BOVIN Ras GTPase-activating protein 1 - Bos taurus (Bovine)| Length = 1044 Score = 33.1 bits (74), Expect = 7.2 Identities = 17/63 (26%), Positives = 31/63 (49%) Frame = +2 Query: 566 TTYDLVEQMQYLYVRVVKAKELPSKDLTGSCDPYVEVKLGNYKGTTRHFEKKTNPEWNQV 745 T+ + Q+ L + + +A +LP K T +PY + L + + H + NP W++ Sbjct: 582 TSNKRLRQVSSLILHIEEAHKLPVKHFT---NPYCNIYLNSVQVAKTHAREGQNPVWSEE 638 Query: 746 FAF 754 F F Sbjct: 639 FVF 641
>Q39055:CNX2_ARATH Molybdopterin biosynthesis protein CNX2 - Arabidopsis thaliana| (Mouse-ear cress) Length = 390 Score = 33.1 bits (74), Expect = 7.2 Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 16/142 (11%) Frame = +2 Query: 1778 NCHLNGGEKANG---ARDTRIGKVRIRLSTLETDRVYTHSYPL-----IVLTPAG---VK 1924 +CHL G + +N + G V ++T ++R+++ SY I P + Sbjct: 10 DCHL-GFKNSNFLLVGSEVGSGSVTRTITTTTSERLFSSSYAAHQVDQIKDNPVSDMLID 68 Query: 1925 KMGEVQLAVRFTCSSLLNMMTLYSQP-----LLPKMHYVHPLSVIQVDNLRRQATNIVST 2089 K G + +R + + N+ Y P L PK + ++++ L A + Sbjct: 69 KFGRLHTYLRISLTERCNLRCQYCMPSEGVELTPKPQLLSQSEIVRLAGLFVSA-GVNKI 127 Query: 2090 RLSRAEPPLRKEIVEYMLDVDS 2155 RL+ EP +RK+I E L + S Sbjct: 128 RLTGGEPTVRKDIEEICLQLSS 149
>Q5U303:TAB2_RAT Mitogen-activated protein kinase kinase kinase 7-interacting| protein 2 - Rattus norvegicus (Rat) Length = 693 Score = 32.7 bits (73), Expect = 9.4 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Frame = -1 Query: 677 SPQHTGHNFQ*GPYLEVPSLLPLEHKGTASAQPGHRWW*ACHLQLPHQGEE*SPSRSTPP 498 +PQ Q GP+ P+ PL H T++ QP + H+ +P SP+ PP Sbjct: 243 NPQQAYQPSQPGPWTTYPASNPLPH--TSTQQPNQQGHQTSHVYMPIS----SPTTPQPP 296 Query: 497 GGMASASS*MTVLN----QTIPTQGRKGR---KIQPTMTDS 396 +SASS + + Q I T RK + K++P +S Sbjct: 297 TVHSSASSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNS 337
>Q7L8C5:SYT13_HUMAN Synaptotagmin-13 - Homo sapiens (Human)| Length = 426 Score = 32.7 bits (73), Expect = 9.4 Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 6/111 (5%) Frame = +2 Query: 926 HKVKGELMLAVWMGTQADEAFPEAWHSDAASIPGDGLASIRSKVYLTPKLWYLRVNVIEA 1105 H V GEL L + + A +A P G + + P L V +I+A Sbjct: 252 HSVAGELRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKA 311 Query: 1106 QDLIPNDKTRF--PEVYVKAMLGNQALRTRVSPGRT----LNPMWNEDLMF 1240 ++L N +V VK L +QA + + + +NP+WNE +MF Sbjct: 312 KNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMF 362
>Q3MJ16:PA24E_HUMAN Cytosolic phospholipase A2 epsilon - Homo sapiens (Human)| Length = 838 Score = 32.7 bits (73), Expect = 9.4 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Frame = +2 Query: 599 LYVRVVKAKELPSKDLTGSCDPYVEVKL---GNYKGTTRHFEKKTNPEWNQVFAF 754 L VRV++ K + D+ D +V + L K TR NPEWN+ F F Sbjct: 52 LTVRVIRMKNVRQADMLSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNF 106
>Q9Z2T6:KRT85_MOUSE Keratin type II cuticular Hb5 - Mus musculus (Mouse)| Length = 507 Score = 32.7 bits (73), Expect = 9.4 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 1/110 (0%) Frame = -1 Query: 2882 VAAIEHARHRATETSKALDREARETVAPYSMLSVLAGSLLKKFSGTDGILWRNLGCLRV- 2706 +A +E A +A + L +E +E + L + + + G + L +G + V Sbjct: 385 LAELEGALQKAKQDMACLLKEYQEVMNSKLALDIEIATYRRLLEGEEQRLCEGVGSVNVC 444 Query: 2705 YRPARKTTTRNGVTYRTIAAMKQKVTNSAVALGSLQLSRDCSLSPCVARS 2556 +R T G+TY T +Q V+ +V GS+ + S SPC R+ Sbjct: 445 VSSSRGGVTCGGLTYGTTPG-RQIVSGPSVTGGSITVMAPDSCSPCQPRA 493
>Q9P2E2:KIF17_HUMAN Kinesin-like protein KIF17 - Homo sapiens (Human)| Length = 1029 Score = 32.7 bits (73), Expect = 9.4 Identities = 13/28 (46%), Positives = 17/28 (60%) Frame = -3 Query: 2580 PLSLCCKITNNSLDPPSDAPEAVVPHPY 2497 P L C ++NNS PP+ APE P P+ Sbjct: 976 PPGLSCPLSNNSAIPPTQAPEMPQPRPF 1003 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 587,046,894 Number of extensions: 13896526 Number of successful extensions: 38774 Number of sequences better than 10.0: 166 Number of HSP's gapped: 38657 Number of HSP's successfully gapped: 373 Length of query: 1022 Length of database: 100,686,439 Length adjustment: 123 Effective length of query: 899 Effective length of database: 66,948,154 Effective search space: 60186390446 Effective search space used: 60186390446 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
