ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf4m07 |
|---|---|
| Clone Library Name | barley_pub |
>P91682:SMO_DROME Protein smoothened precursor - Drosophila melanogaster (Fruit fly)| Length = 1036 Score = 58.9 bits (141), Expect = 8e-08 Identities = 76/353 (21%), Positives = 137/353 (38%), Gaps = 24/353 (6%) Frame = +3 Query: 960 NGQWPCYFPWVNASDKDPNFY-----CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTF 1124 NG C P V +D ++Y C +RC T+ E++Q ++G G + +S Sbjct: 213 NGTGQCLSPLV-PTDTSASYYPGIEGCGVRCKDPLYTDDEHRQIHKLIGWAGSICLLSNL 271 Query: 1125 FVFATMLC-MPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWRKT-VCRD-----HYSP 1283 FV +T +PA +V ++ C I ++ T G R+ VCR H P Sbjct: 272 FVVSTFFIDWKNANKYPAVIVFYINLCFLIACVGWLLQFTSGSREDIVCRKDGTLRHSEP 331 Query: 1284 RWGYHEGNGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLKRDSILRSRWFEIGTHVI 1463 G E V L F G +F + A+ +D I + + H++ Sbjct: 332 TAG--ENLSCIVIFVLVYYFLTAGMVWFVFLTYAWHWRAMGHVQDRIDKKGSY---FHLV 386 Query: 1464 CWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVA 1643 W P T+ +A ++ + + CFV + + G L GP+ I++ Sbjct: 387 AWSLPLVLTITTMAFSEVDGNSIVGICFVGYINHSMRAG--------LLLGPLCGVILIG 438 Query: 1644 ----TGAIVMVL---YEMRNLRAASGSGRFNKHI-RIALFLVVFLGIYAFVFAYRFTITT 1799 T +VM+ + ++++ S S + + I R+ + ++ L A T Sbjct: 439 GYFITRGMVMLFGLKHFANDIKSTSASNKIHLIIMRMGVCALLTLVFILVAIACHVTEFR 498 Query: 1800 DQNKWRASLTTY----ARSAFEGTSQVGLSSKPSYGLFMAFNFFIGIQGALVS 1946 ++W S + S FE S + ++PS G+ + G ++S Sbjct: 499 HADEWAQSFRQFIICKISSVFEEKSSCRIENRPSVGVLQLHLLCLFSSGIVMS 551
>Q9PT62:FZD4_XENLA Frizzled-4 precursor - Xenopus laevis (African clawed frog)| Length = 523 Score = 58.9 bits (141), Expect = 8e-08 Identities = 64/290 (22%), Positives = 121/290 (41%), Gaps = 8/290 (2%) Frame = +3 Query: 918 TAAVPAVNTSAFLQNGQWPCYFPWVNASDKDPNFYCALRC--PSAFRTNFEYKQAEIMMG 1091 T +P + ++F N + WV S C L+C S + +I M Sbjct: 159 TPVLPGEDCNSFGPNSD---QYTWVKRS-----MNCVLKCGYDSGLYNRLSKEFTDIWMA 210 Query: 1092 IIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWRKTVCR- 1268 + L +IST F T L +P ++F+ C +I + A++ +T G + C Sbjct: 211 VWASLCFISTAFTVLTFLIDSSRFCYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDF 270 Query: 1269 DHYSPRWGYHEG--NGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLK--RDSI-LRS 1433 + + EG N C L + F G+ ++ +W + + F+A LK ++I + S Sbjct: 271 EEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHS 330 Query: 1434 RWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSWQYPLFF 1613 +F H+ W P T++ L + + C+V G + PLF Sbjct: 331 SYF----HIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNIDALTGFVVA---PLFT 383 Query: 1614 GPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNKHIRIALFLVVFLGIY 1763 + + +A G ++ L+++R+ G+ + +K R+ + + VF +Y Sbjct: 384 YLVIGTLFIAAG--LVALFKIRSNLQKDGT-KTDKLERLMVKIGVFSVLY 430
>O00144:FZD9_HUMAN Frizzled-9 precursor - Homo sapiens (Human)| Length = 591 Score = 58.5 bits (140), Expect = 1e-07 Identities = 71/359 (19%), Positives = 133/359 (37%), Gaps = 26/359 (7%) Frame = +3 Query: 1023 CALRCP---SAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFV 1193 CA RC F + + A + M + L + ST F T L P +P ++F+ Sbjct: 211 CAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFL 270 Query: 1194 LFCSHILAFAFVFTITRGWRKTVCRDHYSPRWGYHEG--NGACVFNALTVIFGGLGTTFF 1367 C ++ + AF+ G + C + EG N C L + + G+ ++ + Sbjct: 271 SMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFLLLYYFGMASSLW 330 Query: 1368 WCAVAINSFIAIYLK--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 W + + F+A K ++I +F H+ WG P T++ L +++ Sbjct: 331 WVVLTLTWFLAAGKKWGHEAIEAHGSYF----HMAAWGLPALKTIVILTLRKVAGDELTG 386 Query: 1539 FCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVM----------VLYEMRNLR 1688 C+V D A + GF +V +G +V+ L+ +R + Sbjct: 387 LCYVAS-----TDAAALT----------GFVLVPLSGYLVLGSSFLLTGFVALFHIRKIM 431 Query: 1689 AASGSG--RFNK-HIRIALFLVVFLGIYAFVFAYRFTITTDQNKWRASLTTYARSAFEGT 1859 G+ + K ++I +F +++ V + + WR T +A G Sbjct: 432 KTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCAAAAGP 491 Query: 1860 S-----QVGLSSKPSYGLFMAFNFFIGIQGALVSILFGSNTDVLTFWGERVQNIREGRS 2021 + S P+ +FM F + G + S+ T+ + I GR+ Sbjct: 492 GGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYRKIAAGRA 550
>Q99835:SMO_HUMAN Smoothened homolog precursor - Homo sapiens (Human)| Length = 787 Score = 57.8 bits (138), Expect = 2e-07 Identities = 71/330 (21%), Positives = 131/330 (39%), Gaps = 22/330 (6%) Frame = +3 Query: 960 NGQWPCYFPWVNASDKDPNFY-----CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTF 1124 N C P V +D ++Y C ++C + T E++ + G ++ + T Sbjct: 188 NSSGQCEVPLVR-TDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTL 246 Query: 1125 FVFATMLCMPRYRH-FPANLVLFVLFCSHILAFAFVFTITRGWRKT-VCRDHYSPRWGYH 1298 F AT + R + +PA ++ +V C + + ++ G R+ VCR + R G Sbjct: 247 FTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEP 306 Query: 1299 EGNG--ACVFNALTVIFGGLGTTFFWCAVAI----NSFIAIYLKRDSIL-RSRWFEIGTH 1457 N +CV +++ L W V SF A+ + ++ +F H Sbjct: 307 TSNETLSCVI-IFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYF----H 361 Query: 1458 VICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIV 1637 ++ W PF T+ LA Q+ + CFV Y + G PIG ++ Sbjct: 362 LLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAG--------FVLAPIGLVLI 413 Query: 1638 VATGAI---VMVLYEMRN----LRAASGSGRFNK-HIRIALFLVVFLGIYAFVFAYRFTI 1793 V + VM L+ +++ L + + + N+ +R+ +F + G F+ F Sbjct: 414 VGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYD 473 Query: 1794 TTDQNKWRASLTTYARSAFEGTSQVGLSSK 1883 +Q +W S Y + +GL +K Sbjct: 474 FFNQAEWERSFRDYV--LCQANVTIGLPTK 501
>Q9R216:FZD9_MOUSE Frizzled-9 precursor - Mus musculus (Mouse)| Length = 592 Score = 57.4 bits (137), Expect = 2e-07 Identities = 43/189 (22%), Positives = 77/189 (40%), Gaps = 9/189 (4%) Frame = +3 Query: 1023 CALRCP---SAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFV 1193 CA RC F + + A + M + L + ST F T L P +P ++F+ Sbjct: 212 CAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVFTFLLEPHRFQYPERPIIFL 271 Query: 1194 LFCSHILAFAFVFTITRGWRKTVCRDHYSPRWGYHEG--NGACVFNALTVIFGGLGTTFF 1367 C ++ + AF+ G + C + EG N C L + + G+ ++ + Sbjct: 272 SMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFLLLYYFGMASSLW 331 Query: 1368 WCAVAINSFIAIYLK--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 W + + F+A K ++I +F H+ WG P T++ L +++ Sbjct: 332 WVVLTLTWFLAAGKKWGHEAIEAHGSYF----HMAAWGLPALKTIVVLTLRKVAGDELTG 387 Query: 1539 FCFVTE-DP 1562 C+V DP Sbjct: 388 LCYVASMDP 396
>Q8CHL0:FZD5_RAT Frizzled-5 precursor - Rattus norvegicus (Rat)| Length = 585 Score = 57.0 bits (136), Expect = 3e-07 Identities = 67/311 (21%), Positives = 122/311 (39%), Gaps = 7/311 (2%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLC-MPRYRHFPANLVLFVLF 1199 CA+ C + E A +G+ L +IST AT L M R+R +P ++F+ Sbjct: 218 CAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFR-YPERPIIFLSA 276 Query: 1200 CSHILAFAFVFTITRGWRKTVCRDHYSPRWGYHEGNGACVFNALTVIFGGLGTTFFWCAV 1379 C ++ F+ + G C +S G C L V F G+ ++ +W + Sbjct: 277 CYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPALCTVVFLLVYFFGMASSIWWVIL 336 Query: 1380 AINSFIAIYLKRDSILRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTED 1559 ++ F+A +K + + + + H+ W P ++ ALA + C+V Sbjct: 337 SLTWFLAAGMKWGNEAIAGYAQY-FHLAAWLIPSVKSITALALSSVDGDPVAGVCYVGNQ 395 Query: 1560 PYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAA--SGSGRFNK----H 1721 + G GP+ ++V T ++ + +R+ G + +K Sbjct: 396 NLNSLRG--------FVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLM 447 Query: 1722 IRIALFLVVFLGIYAFVFAYRFTITTDQNKWRASLTTYARSAFEGTSQVGLSSKPSYGLF 1901 IRI +F +++ + V A + W A+LT A G+ +KP Y + Sbjct: 448 IRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALT----CACPGSDAGQPRAKPEYWVL 503 Query: 1902 MAFNFFIGIQG 1934 M F + G Sbjct: 504 MLKYFMCLVVG 514
>P97698:SMO_RAT Smoothened homolog precursor - Rattus norvegicus (Rat)| Length = 793 Score = 56.6 bits (135), Expect = 4e-07 Identities = 70/330 (21%), Positives = 132/330 (40%), Gaps = 22/330 (6%) Frame = +3 Query: 960 NGQWPCYFPWVNASDKDPNFY-----CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTF 1124 N C P V +D ++Y C ++C + T E++ + G ++ + T Sbjct: 192 NSSGQCEAPLVR-TDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTL 250 Query: 1125 FVFATMLCMPRYRH-FPANLVLFVLFCSHILAFAFVFTITRGWRKT-VCRDHYSPRWGYH 1298 F AT + R + +PA ++ +V C + + ++ G R+ VCR + R+G Sbjct: 251 FTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRFGEP 310 Query: 1299 EGNG--ACVFNALTVIFGGLGTTFFWCAVAI----NSFIAIYLKRDSIL-RSRWFEIGTH 1457 + +CV +++ L W V SF A+ + ++ +F H Sbjct: 311 TSSETLSCVI-IFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYF----H 365 Query: 1458 VICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIV 1637 ++ W PF T+ LA Q+ + CFV Y + G PIG ++ Sbjct: 366 LLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAG--------FVLAPIGLVLI 417 Query: 1638 VATGAI---VMVLYEMRN----LRAASGSGRFNK-HIRIALFLVVFLGIYAFVFAYRFTI 1793 V + VM L+ +++ L + + + N+ +R+ +F + G F+ F Sbjct: 418 VGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYD 477 Query: 1794 TTDQNKWRASLTTYARSAFEGTSQVGLSSK 1883 +Q +W S Y + +GL +K Sbjct: 478 FFNQAEWERSFRDYV--LCQANVTIGLPTK 505
>Q9IA05:FZD4_CHICK Frizzled-4 precursor - Gallus gallus (Chicken)| Length = 525 Score = 56.6 bits (135), Expect = 4e-07 Identities = 57/258 (22%), Positives = 111/258 (43%), Gaps = 8/258 (3%) Frame = +3 Query: 1014 NFYCALRC--PSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVL 1187 N C L+C + + + +I M + L +IST F T L +P ++ Sbjct: 185 NLDCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPII 244 Query: 1188 FVLFCSHILAFAFVFTITRGWRKTVCR-DHYSPRWGYHEG--NGACVFNALTVIFGGLGT 1358 F+ C +I + A++ +T G + C + + EG N C L + F G+ + Sbjct: 245 FLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMAS 304 Query: 1359 TFFWCAVAINSFIAIYLK--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPN 1529 + +W + + F+A LK ++I + S +F H+ W P T++ L + + Sbjct: 305 SIWWVILTLTWFLAAGLKWGHEAIEMHSSYF----HIAAWAIPAVKTIVILIMRLVDADE 360 Query: 1530 QLLFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGR 1709 C+V G + PLF + + +A G ++ L+++R+ G+ + Sbjct: 361 LTGLCYVGNQNLDALTGFVVA---PLFTYLVIGTLFIAAG--LVALFKIRSNLQKDGT-K 414 Query: 1710 FNKHIRIALFLVVFLGIY 1763 +K R+ + + VF +Y Sbjct: 415 TDKLERLMVKIGVFSVLY 432
>O42224:SMO_CHICK Smoothened homolog precursor - Gallus gallus (Chicken)| Length = 794 Score = 55.8 bits (133), Expect = 7e-07 Identities = 64/288 (22%), Positives = 117/288 (40%), Gaps = 17/288 (5%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRH-FPANLVLFVLF 1199 C ++C + T E+++ + + ++ TFF AT + R + +PA ++ +V Sbjct: 183 CGIQCQNPLFTETEHREMHVYIAFSS-VTISCTFFTLATFVADWRNSNRYPAVILFYVNA 241 Query: 1200 CSHILAFAFVFTITRGWR-KTVCRDHYSPRWGYHEGNG--ACVFNALTVIFGGLGTTFFW 1370 C + + V G R + VCR + R G N +CV +++ L + W Sbjct: 242 CFFVGSIGCVAQFMDGARDEIVCRADGTMRLGEPTSNETLSCVI-IFVIVYYSLMSGVIW 300 Query: 1371 CAVAI----NSFIAIYLKRDSIL-RSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQL 1535 + SF A+ +L ++ +F H+I W PF T+ LA Q+ + Sbjct: 301 FVMLTYAWHTSFKALGTTYQPLLGKTSYF----HLITWSIPFVLTVAILAVAQVDGDSVS 356 Query: 1536 LFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAI---VMVLYEMRN----LRAA 1694 CFV Y + G PIG ++V + VM L+ +++ L + Sbjct: 357 GICFVGYKNYRYRAG--------FVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLLSE 408 Query: 1695 SGSGRFNK-HIRIALFLVVFLGIYAFVFAYRFTITTDQNKWRASLTTY 1835 + + N+ +R+ +F + G F F +Q +W S Y Sbjct: 409 KAASKINETMLRLGIFGFLAFGFVFITFGCHFYDFFNQAEWERSFREY 456
>Q9IA02:FZD9_CHICK Frizzled-9 - Gallus gallus (Chicken)| Length = 392 Score = 55.8 bits (133), Expect = 7e-07 Identities = 65/338 (19%), Positives = 127/338 (37%), Gaps = 17/338 (5%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAE---IMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFV 1193 CA RC + + + + M + L ++ST F T L P +P ++F+ Sbjct: 17 CAPRCSPGVDVYWSREDKDFAFVWMAVWSTLCFVSTAFTVLTFLLDPHRFQYPERPIIFL 76 Query: 1194 LFCSHILAFAFVFTITRGWRKTVCRDHYSPRWGYHEG--NGACVFNALTVIFGGLGTTFF 1367 C ++ + AF+ G C + EG + C L + + G+ ++ + Sbjct: 77 SMCYNVYSVAFIIRSVAGAETIACDRENGELYIIQEGLESTGCTIVFLILYYFGMASSLW 136 Query: 1368 WCAVAINSFIAIYLK--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 W + + F+A K ++I S +F H+ WG P T++ L +++ Sbjct: 137 WVVLTLTWFLAAGKKWGHEAIEAHSSYF----HMAAWGIPAMKTIVILTMRKVAGDELTG 192 Query: 1539 FCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIV---MVLYEMRNLRAASGSG- 1706 C+V G P+ +VV T I+ + L+ +R + G+ Sbjct: 193 LCYVGSMDVSALTG--------FVLIPLSCYLVVGTSFILTGFVALFHIRKIMKTGGTNT 244 Query: 1707 -RFNK-HIRIALFLVVFLGIYAFVFAYRFTITTDQNKWRASLTTYARSAFEGTSQVGLS- 1877 + K ++I +F +++ V F + + W A G S Sbjct: 245 EKLEKLMVKIGVFSILYTVPATCVIVCYFYERLNVDYWNLRALERACVPLPGRRAADCSL 304 Query: 1878 --SKPSYGLFMAFNFFIGIQGALVSILFGSNTDVLTFW 1985 S P+ +FM F+ + + S ++ ++ L W Sbjct: 305 EASVPTVAVFM-LKIFMSLVVGITSGVWVWSSKTLQTW 341
>Q13467:FZD5_HUMAN Frizzled-5 precursor - Homo sapiens (Human)| Length = 585 Score = 55.8 bits (133), Expect = 7e-07 Identities = 68/324 (20%), Positives = 124/324 (38%), Gaps = 7/324 (2%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLC-MPRYRHFPANLVLFVLF 1199 CA+ C + E A +G+ L +IST AT L M R+R +P ++F+ Sbjct: 218 CAVPCYQPSFSADERTFATFWIGLWSVLCFISTSTTVATFLIDMERFR-YPERPIIFLSA 276 Query: 1200 CSHILAFAFVFTITRGWRKTVCRDHYSPRWGYHEGNGACVFNALTVIFGGLGTTFFWCAV 1379 C ++ F+ + G C ++ G C L V F G+ ++ +W + Sbjct: 277 CYLCVSLGFLVRLVVGHASVACSREHNHIHYETTGPALCTIVFLLVYFFGMASSIWWVIL 336 Query: 1380 AINSFIAIYLKRDSILRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTED 1559 ++ F+A +K + + + + H+ W P ++ ALA + C+V Sbjct: 337 SLTWFLAAGMKWGNEAIAGYAQY-FHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQ 395 Query: 1560 PYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAA--SGSGRFNK----H 1721 + G GP+ ++V T ++ + +R+ G + +K Sbjct: 396 NLNSLRG--------FVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLM 447 Query: 1722 IRIALFLVVFLGIYAFVFAYRFTITTDQNKWRASLTTYARSAFEGTSQVGLSSKPSYGLF 1901 IRI +F +++ + V A + W A+LT A G +KP Y + Sbjct: 448 IRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALT----CACPGHDTGQPRAKPEYWVL 503 Query: 1902 MAFNFFIGIQGALVSILFGSNTDV 1973 M F + G + S V Sbjct: 504 MLKYFMCLVVGITSGVWIWSGKTV 527
>Q9QZH0:FZD4_RAT Frizzled-4 precursor - Rattus norvegicus (Rat)| Length = 538 Score = 55.8 bits (133), Expect = 7e-07 Identities = 56/255 (21%), Positives = 110/255 (43%), Gaps = 8/255 (3%) Frame = +3 Query: 1023 CALRC--PSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVL 1196 C L+C + + + +I M + L +IST F T L +P ++F+ Sbjct: 201 CVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTTFTVLTFLIDSSRFSYPERPIIFLS 260 Query: 1197 FCSHILAFAFVFTITRGWRKTVCR-DHYSPRWGYHEG--NGACVFNALTVIFGGLGTTFF 1367 C +I + A++ +T G + C + + EG N C L + F G+ ++ + Sbjct: 261 MCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIW 320 Query: 1368 WCAVAINSFIAIYLK--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 W + + F+A LK ++I + S +F H+ W P T++ L + + Sbjct: 321 WVILTLTWFLAAGLKWGHEAIEMHSSYF----HIAAWAIPAVKTIVILIMRLVDADELTG 376 Query: 1539 FCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNK 1718 C+V G + PLF + + +A G ++ L+++R+ G+ + +K Sbjct: 377 LCYVGNQSLDALTGFVVA---PLFTYLVIGTLFIAAG--LVALFKIRSNLQKDGT-KTDK 430 Query: 1719 HIRIALFLVVFLGIY 1763 R+ + + VF +Y Sbjct: 431 LERLMVKIGVFSVLY 445
>P56726:SMO_MOUSE Smoothened homolog precursor - Mus musculus (Mouse)| Length = 793 Score = 55.5 bits (132), Expect = 9e-07 Identities = 70/330 (21%), Positives = 131/330 (39%), Gaps = 22/330 (6%) Frame = +3 Query: 960 NGQWPCYFPWVNASDKDPNFY-----CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTF 1124 N C P V +D ++Y C ++C + T E++ + G ++ + T Sbjct: 192 NSSGQCEAPLVR-TDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTL 250 Query: 1125 FVFATMLCMPRYRH-FPANLVLFVLFCSHILAFAFVFTITRGWRKT-VCRDHYSPRWGYH 1298 F AT + R + PA ++ +V C + + ++ G R+ VCR + R+G Sbjct: 251 FTLATFVADWRNSNRLPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRFGEP 310 Query: 1299 EGNG--ACVFNALTVIFGGLGTTFFWCAVAI----NSFIAIYLKRDSIL-RSRWFEIGTH 1457 + +CV +++ L W V SF A+ + ++ +F H Sbjct: 311 TSSETLSCVI-IFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYF----H 365 Query: 1458 VICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIV 1637 ++ W PF T+ LA Q+ + CFV Y + G PIG ++ Sbjct: 366 LLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAG--------FVLAPIGLVLI 417 Query: 1638 VATGAI---VMVLYEMRN----LRAASGSGRFNK-HIRIALFLVVFLGIYAFVFAYRFTI 1793 V + VM L+ +++ L + + + N+ +R+ +F + G F+ F Sbjct: 418 VGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYD 477 Query: 1794 TTDQNKWRASLTTYARSAFEGTSQVGLSSK 1883 +Q +W S Y + +GL +K Sbjct: 478 FFNQAEWERSFRDYV--LCQANVTIGLPTK 505
>Q61088:FZD4_MOUSE Frizzled-4 precursor - Mus musculus (Mouse)| Length = 537 Score = 55.5 bits (132), Expect = 9e-07 Identities = 56/255 (21%), Positives = 110/255 (43%), Gaps = 8/255 (3%) Frame = +3 Query: 1023 CALRC--PSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVL 1196 C L+C + + + +I M + L +IST F T L +P ++F+ Sbjct: 200 CVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTTFTVLTFLIDSSRFSYPERPIIFLS 259 Query: 1197 FCSHILAFAFVFTITRGWRKTVCR-DHYSPRWGYHEG--NGACVFNALTVIFGGLGTTFF 1367 C +I + A++ +T G + C + + EG N C L + F G+ ++ + Sbjct: 260 MCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIW 319 Query: 1368 WCAVAINSFIAIYLK--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 W + + F+A LK ++I + S +F H+ W P T++ L + + Sbjct: 320 WVILTLTWFLAAGLKWGHEAIEMHSSYF----HIAAWAIPAVKTIVILIMRLVDADELTG 375 Query: 1539 FCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNK 1718 C+V G + PLF + + +A G ++ L+++R+ G+ + +K Sbjct: 376 LCYVGNQNLDALTGFVVA---PLFTYLVIGTLFIAAG--LVALFKIRSNLQKDGT-KTDK 429 Query: 1719 HIRIALFLVVFLGIY 1763 R+ + + VF +Y Sbjct: 430 LERLMVKIGVFSVLY 444
>Q9ULV1:FZD4_HUMAN Frizzled-4 precursor - Homo sapiens (Human)| Length = 537 Score = 55.5 bits (132), Expect = 9e-07 Identities = 56/255 (21%), Positives = 110/255 (43%), Gaps = 8/255 (3%) Frame = +3 Query: 1023 CALRC--PSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVL 1196 C L+C + + + +I M + L +IST F T L +P ++F+ Sbjct: 200 CVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLS 259 Query: 1197 FCSHILAFAFVFTITRGWRKTVCR-DHYSPRWGYHEG--NGACVFNALTVIFGGLGTTFF 1367 C +I + A++ +T G + C + + EG N C L + F G+ ++ + Sbjct: 260 MCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIW 319 Query: 1368 WCAVAINSFIAIYLK--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 W + + F+A LK ++I + S +F H+ W P T++ L + + Sbjct: 320 WVILTLTWFLAAGLKWGHEAIEMHSSYF----HIAAWAIPAVKTIVILIMRLVDADELTG 375 Query: 1539 FCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNK 1718 C+V G + PLF + + +A G ++ L+++R+ G+ + +K Sbjct: 376 LCYVGNQNLDALTGFVVA---PLFTYLVIGTLFIAAG--LVALFKIRSNLQKDGT-KTDK 429 Query: 1719 HIRIALFLVVFLGIY 1763 R+ + + VF +Y Sbjct: 430 LERLMVKIGVFSVLY 444
>Q5RCN4:FZD6_PONPY Frizzled-6 precursor - Pongo pygmaeus (Orangutan)| Length = 707 Score = 54.7 bits (130), Expect = 2e-06 Identities = 60/277 (21%), Positives = 101/277 (36%), Gaps = 21/277 (7%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFC 1202 CA CP+ + + E + A+ +G + +T F F T L R +P +++ C Sbjct: 182 CAPPCPNMYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVC 241 Query: 1203 SHILAFAFVFTITRGWRKTVCRD-----HYSPRWGYHEGNGACVFNALTVIFGGLGTTFF 1367 I++ + G T C N AC + + F + T + Sbjct: 242 YSIVSLMYFIGFLLG-DSTACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGTVW 300 Query: 1368 WCAVAINSFIAIYLKRDSIL---RSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 W + I F+A K ++ WF H + WGTP T++ LA ++ N Sbjct: 301 WVILTITWFLAAGRKWSCEAIEQKAVWF----HAVAWGTPGFLTVMLLAMNKVEGDNISG 356 Query: 1539 FCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNK 1718 CFV + D + P+ C+ V ++ + + ++R N+ Sbjct: 357 VCFV---GLYDLDASRY-----FVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQ 408 Query: 1719 H------IRIALF-------LVVFLGIYAFVFAYRFT 1790 IRI +F LV LG Y + R T Sbjct: 409 EKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRIT 445
>O60353:FZD6_HUMAN Frizzled-6 precursor - Homo sapiens (Human)| Length = 706 Score = 54.7 bits (130), Expect = 2e-06 Identities = 60/277 (21%), Positives = 101/277 (36%), Gaps = 21/277 (7%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFC 1202 CA CP+ + + E + A+ +G + +T F F T L R +P +++ C Sbjct: 181 CAPPCPNMYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVC 240 Query: 1203 SHILAFAFVFTITRGWRKTVCRD-----HYSPRWGYHEGNGACVFNALTVIFGGLGTTFF 1367 I++ + G T C N AC + + F + T + Sbjct: 241 YSIVSLMYFIGFLLG-DSTACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGTVW 299 Query: 1368 WCAVAINSFIAIYLKRDSIL---RSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 W + I F+A K ++ WF H + WGTP T++ LA ++ N Sbjct: 300 WVILTITWFLAAGRKWSCEAIEQKAVWF----HAVAWGTPGFLTVMLLALNKVEGDNISG 355 Query: 1539 FCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNK 1718 CFV + D + P+ C+ V ++ + + ++R N+ Sbjct: 356 VCFV---GLYDLDASRY-----FVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQ 407 Query: 1719 H------IRIALF-------LVVFLGIYAFVFAYRFT 1790 IRI +F LV LG Y + R T Sbjct: 408 EKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRIT 444
>Q8WMU5:FZD6_CANFA Frizzled-6 precursor - Canis familiaris (Dog)| Length = 712 Score = 54.7 bits (130), Expect = 2e-06 Identities = 59/276 (21%), Positives = 102/276 (36%), Gaps = 20/276 (7%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFC 1202 CA CP+ + + E + A+ +GI+ +T F F T L + +P +++ C Sbjct: 181 CAPPCPNMYFKSDELEFAKSFIGIVSIFCLCATLFTFLTFLIDVKRFRYPERPIIYYSVC 240 Query: 1203 SHILAFAFVFTITRGWRKTVCRDHYSPRWG----YHEGNGACVFNALTVIFGGLGTTFFW 1370 I++ + G R + G N AC + + F + T +W Sbjct: 241 YSIVSLMYFIGFLLGDRTACNKADEKLELGDTVVLGSQNKACTVLFMFLYFFTMAGTVWW 300 Query: 1371 CAVAINSFIAIYLKRDSIL---RSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLF 1541 + I F+A K ++ WF H + WG P T++ LA ++ N Sbjct: 301 VILTITWFLAAGRKWSCEAIEQKAVWF----HAVAWGIPGFLTVMLLAMNKVEGDNISGV 356 Query: 1542 CFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNKH 1721 CFV + D + P+ C+ V ++ + + ++R N+ Sbjct: 357 CFV---GLYDLDASRY-----FVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQE 408 Query: 1722 ------IRIALF-------LVVFLGIYAFVFAYRFT 1790 IRI +F LV LG Y + R T Sbjct: 409 KLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRIT 444
>P58421:FZD5_XENLA Frizzled-5 precursor - Xenopus laevis (African clawed frog)| Length = 559 Score = 54.7 bits (130), Expect = 2e-06 Identities = 58/244 (23%), Positives = 99/244 (40%), Gaps = 17/244 (6%) Frame = +3 Query: 870 YDLSRTRIALPITINTTAAVPAVNTSAFLQNGQWPCYFPWVNASDKDPNFY--------- 1022 Y+ + T LP T P V T +G C P+V+ + + Y Sbjct: 149 YNWTETTTTLPPT-----HPPKVKTPTSDCDGVCKCREPFVSITRESHPLYNRIKTGQVP 203 Query: 1023 -CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLC-MPRYRHFPANLVLFVL 1196 CA+ C + T E +G+ L +ISTF AT L M R+R +P ++F+ Sbjct: 204 NCAMPCFQPYFTQDEKMFVTFWIGLWSILCFISTFTTVATFLIDMERFR-YPERPIIFLS 262 Query: 1197 FCSHILAFAFVFTITRGWRKTVC-RDHYSPRWGYHE--GNGACVFNALTVIFGGLGTTFF 1367 C ++ +V + G C +DH ++E G C L + F G+ ++ + Sbjct: 263 ACYLFVSIGYVVRLIVGHENVACNKDHI-----HYETTGPALCTIVFLLIYFFGMASSIW 317 Query: 1368 WCAVAINSFIAIYLK--RDSILR-SRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 W + F+A +K ++I S++F H+ W P ++ LA + Sbjct: 318 WVILTFTWFLAAGMKWGNEAIASYSQYF----HMAAWLIPSVKSIAVLALSSVDGDPVAG 373 Query: 1539 FCFV 1550 C+V Sbjct: 374 ICYV 377
>Q9EQD0:FZD5_MOUSE Frizzled-5 precursor - Mus musculus (Mouse)| Length = 585 Score = 54.7 bits (130), Expect = 2e-06 Identities = 66/311 (21%), Positives = 120/311 (38%), Gaps = 7/311 (2%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLC-MPRYRHFPANLVLFVLF 1199 CA+ C + E A +G+ L +IST AT L M R+R +P ++F+ Sbjct: 218 CAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFR-YPERPIIFLSA 276 Query: 1200 CSHILAFAFVFTITRGWRKTVCRDHYSPRWGYHEGNGACVFNALTVIFGGLGTTFFWCAV 1379 C ++ F+ + G C +S G C L V F G+ ++ +W + Sbjct: 277 CYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPALCTVVFLLVYFFGMASSIWWVIL 336 Query: 1380 AINSFIAIYLKRDSILRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTED 1559 ++ F+A +K + + + + H+ W P ++ ALA + C+ Sbjct: 337 SLTWFLAAGMKWGNEAIAGYAQY-FHLAAWLIPSVKSITALALSSVDGDPVAGICYGVNQ 395 Query: 1560 PYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAA--SGSGRFNK----H 1721 + G GP+ ++V T ++ + +R+ G + +K Sbjct: 396 NLNSLRG--------FVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLM 447 Query: 1722 IRIALFLVVFLGIYAFVFAYRFTITTDQNKWRASLTTYARSAFEGTSQVGLSSKPSYGLF 1901 IRI +F +++ + V A + W A+LT A G +KP Y + Sbjct: 448 IRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALT----CACPGPDAGQPRAKPEYWVL 503 Query: 1902 MAFNFFIGIQG 1934 M F + G Sbjct: 504 MLKYFMCLVVG 514
>Q61089:FZD6_MOUSE Frizzled-6 precursor - Mus musculus (Mouse)| Length = 709 Score = 54.3 bits (129), Expect = 2e-06 Identities = 60/277 (21%), Positives = 100/277 (36%), Gaps = 21/277 (7%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFC 1202 CA CP+ + + E A+ +GI+ +T F F T L R +P +++ C Sbjct: 181 CAPPCPNMYFKSDELDFAKSFIGIVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVC 240 Query: 1203 SHILAFAFVFTITRGWRKTVCRD-----HYSPRWGYHEGNGACVFNALTVIFGGLGTTFF 1367 I++ + G T C N AC + + F + T + Sbjct: 241 YSIVSLMYFVGFLLG-NSTACNKADEKLELGDTVVLGSKNKACSVVFMFLYFFTMAGTVW 299 Query: 1368 WCAVAINSFIAIYLKRDSIL---RSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 W + I F+A K ++ WF H + WG P T++ LA ++ N Sbjct: 300 WVILTITWFLAAGRKWSCEAIEQKAVWF----HAVAWGAPGFLTVMLLAMNKVEGDNISG 355 Query: 1539 FCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNK 1718 CFV + D + P+ C+ V ++ + + ++R N+ Sbjct: 356 VCFV---GLYDLDASRY-----FVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQ 407 Query: 1719 H------IRIALF-------LVVFLGIYAFVFAYRFT 1790 IRI +F LV LG Y + R T Sbjct: 408 EKLKKFMIRIGVFSGLYLVPLVTLLGCYVYELVNRIT 444
>O93274:FZD8_XENLA Frizzled-8 precursor - Xenopus laevis (African clawed frog)| Length = 581 Score = 53.5 bits (127), Expect = 4e-06 Identities = 84/401 (20%), Positives = 152/401 (37%), Gaps = 35/401 (8%) Frame = +3 Query: 975 CYFPWVNASDKDPNFY----------CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTF 1124 C P V S++ Y CA+ C + F + E E +G+ L + STF Sbjct: 193 CRAPMVQVSNERHPLYNRVRTGQIPNCAMPCHNPFFSPEERTFTEFWIGLWSVLCFASTF 252 Query: 1125 FVFATMLC-MPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWRKTVCRD---------H 1274 +T L M R++ +P ++F+ C +++ ++ + G K C H Sbjct: 253 ATVSTFLIDMERFK-YPERPIIFLSACYLLVSTGYLIRLIAGHEKVACSRGELDLEHIIH 311 Query: 1275 YSPRWGYHEGNGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLK--RDSIL-RSRWFE 1445 Y G C L + F G+ ++ +W +++ F+A +K ++I S++F Sbjct: 312 YET-----TGPALCTLVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYF- 365 Query: 1446 IGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSWQYPLFFGPIG 1625 H+ W P ++ LA + CFV G + F IG Sbjct: 366 ---HLAAWLVPSIKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVIYLF--IG 420 Query: 1626 FCIVVATGAIVMVLYEMRNLRAASG--SGRFNK-HIRIALFLVVFLGIYAFVFAYRFTIT 1796 ++A + L+ +R++ G + + K IRI +F V++ V A F Sbjct: 421 SMFLLAG---FVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFSVLYTVPATIVVACFFYEQ 477 Query: 1797 TDQNKWRASLTTYARSAFEGTSQVGLSSKPSYGLFMAFNFFIGIQGALVSILFGSNTDVL 1976 ++ W A + ++ +P Y +FM F + G + S + Sbjct: 478 HNRQGWEV-----AHNCNSCQPEMAQPHRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLE 532 Query: 1977 TF--------WGERVQNIREGRSFFSGI-TSYTASSKVGAS 2072 ++ WG + G S +S + T T S G+S Sbjct: 533 SWRAFCTRCCWGSKA----TGGSMYSDVSTGLTWRSGTGSS 569
>O42579:FZD3_XENLA Frizzled-3 precursor - Xenopus laevis (African clawed frog)| Length = 664 Score = 51.6 bits (122), Expect = 1e-05 Identities = 62/274 (22%), Positives = 102/274 (37%), Gaps = 20/274 (7%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFC 1202 C+ CP + E A +G+I + +T F F T L +P ++F C Sbjct: 184 CSPPCPHMYFRREELSFARYFIGVISIVCLSATLFTFLTFLIDVTRFRYPERPIIFYAVC 243 Query: 1203 SHILAFAFVFTITRGWRKTVCRDHYSPRW-------GYHEGNGACVFNALTVIFGGLGTT 1361 +++ F K C ++ G H N AC + + F + + Sbjct: 244 YMMVSLIFFIGFLLE-DKVACNGANPSQYKASTVTQGSH--NKACTMLFMVLYFFTMAGS 300 Query: 1362 FFWCAVAINSFIAIYLKRDSILRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLF 1541 +W + I F+A K S + + H WG P T T+I LA +I N Sbjct: 301 VWWVILTITWFLAAVPKWGSEAIEK-KALLFHASAWGIPGTLTIILLAMNKIEGDNISGV 359 Query: 1542 CFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNKH 1721 CFV H + +Y P+ +VV ++ + + +R + N+ Sbjct: 360 CFVGLYDVH-------ALRY-FVLAPLCLDVVVGVSLLLAGIISLNRVRIEIPLEKENQD 411 Query: 1722 ------IRIALF-------LVVFLGIYAFVFAYR 1784 IRI +F L+V +G Y + AYR Sbjct: 412 KLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYR 445
>Q9NPG1:FZD3_HUMAN Frizzled-3 precursor - Homo sapiens (Human)| Length = 666 Score = 51.2 bits (121), Expect = 2e-05 Identities = 59/271 (21%), Positives = 100/271 (36%), Gaps = 17/271 (6%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFC 1202 C+ CP+ + E A +G+I + +T F F T L +P ++F C Sbjct: 185 CSPPCPNMYFRREELSFARYFIGLISIICLSATLFTFLTFLIDVTRFRYPERPIIFYAVC 244 Query: 1203 ----SHILAFAFVFTITRGWRKTVCRDHYSPRWGYHEGNGACVFNALTVIFGGLGTTFFW 1370 S I F+ ++ + + N AC + + F + + +W Sbjct: 245 YMMVSLIFFIGFLLEDRVACNASIPAQYKASTVTQGSHNKACTMLFMILYFFTMAGSVWW 304 Query: 1371 CAVAINSFIAIYLKRDSILRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFV 1550 + I F+A K S + + H WG P T T+I LA +I N CFV Sbjct: 305 VILTITWFLAAVPKWGSEAIEK-KALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFV 363 Query: 1551 TEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNKH--- 1721 + D + P+ +VV ++ + + +R + N+ Sbjct: 364 ---GLYDVDALRY-----FVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLEKENQDKLV 415 Query: 1722 ---IRIALF-------LVVFLGIYAFVFAYR 1784 IRI +F L+V +G Y + AYR Sbjct: 416 KFMIRIGVFSILYLVPLLVVIGCYFYEQAYR 446
>Q61086:FZD3_MOUSE Frizzled-3 precursor - Mus musculus (Mouse)| Length = 666 Score = 50.8 bits (120), Expect = 2e-05 Identities = 63/275 (22%), Positives = 103/275 (37%), Gaps = 21/275 (7%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFC 1202 C+ CP+ + E A +G+I + +T F F T L +P ++F C Sbjct: 185 CSPPCPNMYFRREELSFARYFIGLISIICLSATLFTFLTFLIDVTRFRYPERPIIFYAVC 244 Query: 1203 SHILAFAFVFTITRGWRKTVCRDHYSP--------RWGYHEGNGACVFNALTVIFGGLGT 1358 + + +F I V + SP G H N AC + + F + Sbjct: 245 --YMMVSLIFFIGFLLEDRVACNASSPAQYKASTVTQGSH--NKACTMLFMVLYFFTMAG 300 Query: 1359 TFFWCAVAINSFIAIYLKRDSILRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLL 1538 + +W + I F+A K S + + H WG P T T+I LA +I N Sbjct: 301 SVWWVILTITWFLAAVPKWGSEAIEK-KALLFHASAWGIPGTLTIILLAMNKIEGDNISG 359 Query: 1539 FCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNK 1718 CFV + D + P+ +VV ++ + + +R + N+ Sbjct: 360 VCFV---GLYDVDALRY-----FVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLEKENQ 411 Query: 1719 H------IRIALF-------LVVFLGIYAFVFAYR 1784 IRI +F L+V +G Y + AYR Sbjct: 412 DKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYR 446
>Q9ULW2:FZD10_HUMAN Frizzled-10 precursor - Homo sapiens (Human)| Length = 581 Score = 48.9 bits (115), Expect = 9e-05 Identities = 56/301 (18%), Positives = 112/301 (37%), Gaps = 14/301 (4%) Frame = +3 Query: 1074 AEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWR 1253 A + + I L + S+ F T L P +P ++F+ C + + ++ + G Sbjct: 227 AVVWLAIWAVLCFFSSAFTVLTFLIDPARFRYPERPIIFLSMCYCVYSVGYLIRLFAGAE 286 Query: 1254 KTVCRDHYSPRWGYHEG--NGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLK--RDS 1421 C + EG + C L + + G+ ++ +W + + F+A K ++ Sbjct: 287 SIACDRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEA 346 Query: 1422 I-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSWQ 1598 I S +F H+ W P T++ L +++ C+V + G Sbjct: 347 IEANSSYF----HLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTG------ 396 Query: 1599 YPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNKH------IRIALFLVVFLGI 1760 P+ +V+ T I+ + ++R +G N +RI LF V++ Sbjct: 397 --FVLIPLACYLVIGTSFILSGFVALFHIRRVMKTGGENTDKLEKLMVRIGLFSVLYTVP 454 Query: 1761 YAFVFAYRFTITTDQNKWRASLTTYARSAFEGTSQVG---LSSKPSYGLFMAFNFFIGIQ 1931 V A F + + W+ + T + +S P+ +FM F + + Sbjct: 455 ATCVIACYFYERLNMDYWKILAAQHKCKMNNQTKTLDCLMAASIPAVEIFMVKIFMLLVV 514 Query: 1932 G 1934 G Sbjct: 515 G 515
>Q8BKG4:FZD10_MOUSE Frizzled-10 precursor - Mus musculus (Mouse)| Length = 582 Score = 48.1 bits (113), Expect = 1e-04 Identities = 48/265 (18%), Positives = 100/265 (37%), Gaps = 11/265 (4%) Frame = +3 Query: 1074 AEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWR 1253 A + + I L + S+ F T L P +P ++F+ C + + ++ + G Sbjct: 228 AVVWLAIWSVLCFFSSAFTVLTFLIDPSRFRYPERPIIFLSMCYCVYSVGYIIRLFAGAE 287 Query: 1254 KTVCRDHYSPRWGYHEG--NGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLK--RDS 1421 C + EG + C L + + G+ ++ +W + + F+A K ++ Sbjct: 288 SIACDRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEA 347 Query: 1422 I-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSWQ 1598 I S +F H+ W P T++ L +++ C+V + G Sbjct: 348 IEANSSYF----HLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTG------ 397 Query: 1599 YPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASGSGRFNKH------IRIALFLVVFLGI 1760 P+ +V+ T I+ + ++R +G N +RI +F +++ Sbjct: 398 --FVLVPLACYLVIGTSFILSGFVALFHIRRVMKTGGENTDKLEKLMVRIGVFSLLYTVP 455 Query: 1761 YAFVFAYRFTITTDQNKWRASLTTY 1835 V A F + + W+ T + Sbjct: 456 ATCVIACYFYERLNMDYWKMLATQH 480
>Q9I9M5:FZD1_XENLA Frizzled-1 precursor - Xenopus laevis (African clawed frog)| Length = 559 Score = 46.6 bits (109), Expect = 4e-04 Identities = 73/353 (20%), Positives = 139/353 (39%), Gaps = 14/353 (3%) Frame = +3 Query: 1062 EYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTIT 1241 E A I +GI L ST F T L + +P ++F+ C ++A A++ Sbjct: 234 ELNFARIWIGIWSVLCCASTLFTVLTYLVDMKRFSYPERPIIFLSGCYTMVAIAYIAGFL 293 Query: 1242 RGWRKTVCRDHYSPRWGYHEGNGA----CVFNALTVIFGGLGTTFFWCAVAINSFIAIYL 1409 K VC + ++ G C F + + F + ++ +W +++ F+A + Sbjct: 294 LE-DKVVCNERFAEDGYKTVAQGTKKEGCTFLFMMLYFFSMASSIWWVILSLTWFLAAGM 352 Query: 1410 K--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDG 1580 K ++I S++F H+ W P T+ LA Q+ CFV + G Sbjct: 353 KWGHEAIEANSQYF----HLAAWAVPAIKTITILAVGQVDGDTLSGVCFVGINNVDALRG 408 Query: 1581 KAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASG--SGRFNK-HIRIALFLVVF 1751 + + F F + A + L+ +R + G + + K +RI +F V++ Sbjct: 409 FVLAPLFVYLFIGTSFLL-----AGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGIFSVLY 463 Query: 1752 LGIYAFVFAYRFTITTDQNKWRASLTTYARSAF----EGTSQVGLSSKPSYGLFMAFNFF 1919 V A F + +W S + + + T +S P + +FM Sbjct: 464 TVPATIVIACYFYEQAFREQWEKSWISQSCKTYAIPCPSTGHPPMS--PDFTVFMI---- 517 Query: 1920 IGIQGALVSILFGSNTDVLTFWGERVQNIREGRSFFSGITSYTASSKVGASSV 2078 L++++ G + FW + + R F++ +T +SK G ++V Sbjct: 518 ----KYLMTLIVGITSG---FWIWSGKTLNSWRKFYTRLT----NSKQGETTV 559
>O57328:FZD1_CHICK Frizzled-1 precursor - Gallus gallus (Chicken)| Length = 592 Score = 45.4 bits (106), Expect = 0.001 Identities = 70/349 (20%), Positives = 141/349 (40%), Gaps = 10/349 (2%) Frame = +3 Query: 1062 EYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTIT 1241 E + + +GI L ST F T L + +P ++F+ C +A A++ Sbjct: 264 ELRFSRTWIGIWSVLCCASTLFTVLTYLVDMKRFSYPERPIIFLSGCYTAVAVAYIAGFL 323 Query: 1242 RGWRKTVCRDHYSPRWGYHEGNGA----CVFNALTVIFGGLGTTFFWCAVAINSFIAIYL 1409 R VC + ++ G C + + F G+ ++ +W +++ F+A + Sbjct: 324 LEER-VVCNERFAEDGSRTVAQGTKREGCTILFMMLYFFGMASSIWWVILSLTWFLAAGM 382 Query: 1410 K--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDG 1580 K ++I S++F H+ W P T+ LA Q+ CFV + G Sbjct: 383 KWGHEAIEANSQYF----HLAAWAVPAIKTITILALGQVDGDVLSGVCFVGINNVDALRG 438 Query: 1581 KAFSWQYPLFFGPIGFCIVVATGAIVMVLYEMRNLRAASG--SGRFNK-HIRIALFLVVF 1751 + + F F + A + L+ +R + G + + K +RI +F V++ Sbjct: 439 FVLAPLFVYLFIGTSFLL-----AGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGIFSVLY 493 Query: 1752 LGIYAFVFAYRFTITTDQNKWRASLTTYARSAFEGTSQVGLSSKPSYGLFMAFNFFIGIQ 1931 V A F + +W S T + ++ ++ S+ M+ +F + + Sbjct: 494 TVPATIVIACYFYEQAFREQWERSWVTQSCKSYAIPCP---NNHSSHHPPMSPDFTVFMI 550 Query: 1932 GALVSILFGSNTDVLTFWGERVQNIREGRSFFSGITSYTASSKVGASSV 2078 L++++ G + FW + + R F++ +T +SK G ++V Sbjct: 551 KYLMTLIVGITSG---FWIWSGKTLNSWRKFYTRLT----NSKQGETTV 592
>Q61091:FZD8_MOUSE Frizzled-8 precursor - Mus musculus (Mouse)| Length = 685 Score = 45.1 bits (105), Expect = 0.001 Identities = 77/382 (20%), Positives = 139/382 (36%), Gaps = 62/382 (16%) Frame = +3 Query: 975 CYFPWVNASDKDPNFY----------CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTF 1124 C P V+ S + Y CAL C + F + E +G+ L ++STF Sbjct: 231 CRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTF 290 Query: 1125 FVFATMLC-MPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWRKTVC------------ 1265 +T L M R++ +P ++F+ C ++ ++ + G K C Sbjct: 291 ATVSTFLIDMERFK-YPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGRGG 349 Query: 1266 -------------RDHYSP--RWGYHE-------------GNGACVFNALTVIFGGLGTT 1361 R SP R Y E G C L V F G+ ++ Sbjct: 350 AGGAAAAGAGAAGRGASSPGARGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASS 409 Query: 1362 FFWCAVAINSFIAIYLK--RDSIL-RSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQ 1532 +W +++ F+A +K ++I S++F H+ W P ++ LA + Sbjct: 410 IWWVILSLTWFLAAGMKWGNEAIAGYSQYF----HLAAWLVPSVKSIAVLALSSVDGDPV 465 Query: 1533 LLFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIV---MVLYEMRN-LRAASG 1700 C+V G P+ + + T ++ + L+ +R+ ++ G Sbjct: 466 AGICYVGNQSLDNLRG--------FVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQGG 517 Query: 1701 SGRFNK----HIRIALFLVVFLGIYAFVFAYRFTITTDQNKWRASLTTYARSAFEGTSQV 1868 + +K IR+ LF V++ A V A F ++ +W A+ Q Sbjct: 518 PTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDL----QP 573 Query: 1869 GLSSKPSYGLFMAFNFFIGIQG 1934 + +P Y +FM F + G Sbjct: 574 DQARRPDYAVFMLKYFMCLVVG 595
>Q5BL72:FZD7_XENTR Frizzled-7 precursor - Xenopus tropicalis (Western clawed frog)| (Silurana tropicalis) Length = 548 Score = 43.5 bits (101), Expect = 0.004 Identities = 40/162 (24%), Positives = 72/162 (44%), Gaps = 10/162 (6%) Frame = +3 Query: 1062 EYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTIT 1241 E + A + +GI L IST F T L R +P ++F+ C ++A A+ T Sbjct: 223 EVRFARLWVGIWAILCGISTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAY----T 278 Query: 1242 RGW---RKTVCRDHYSPRWGYHEGNGA----CVFNALTVIFGGLGTTFFWCAVAINSFIA 1400 G+ + VC + +S G C + + F G+ ++ +W +++ F+A Sbjct: 279 AGFLLEERGVCVERFSEDSYRTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLA 338 Query: 1401 IYLK--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQI 1517 +K ++I S++F H+ W P T+ LA Q+ Sbjct: 339 AGMKWGHEAIEANSQYF----HLAAWAVPAVKTITILAMGQV 376
>Q9H461:FZD8_HUMAN Frizzled-8 precursor - Homo sapiens (Human)| Length = 694 Score = 43.1 bits (100), Expect = 0.005 Identities = 73/381 (19%), Positives = 136/381 (35%), Gaps = 61/381 (16%) Frame = +3 Query: 975 CYFPWVNASDKDPNFY----------CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTF 1124 C P V+ S + Y CAL C + F + E +G+ L ++STF Sbjct: 234 CRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTF 293 Query: 1125 FVFATMLC-MPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWRKTVC------------ 1265 +T L M R++ +P ++F+ C ++ ++ + G K C Sbjct: 294 ATVSTFLIDMERFK-YPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGG 352 Query: 1266 --------------------RDHYSPRWGYHE-------GNGACVFNALTVIFGGLGTTF 1364 R Y + G C L V F G+ ++ Sbjct: 353 AGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSI 412 Query: 1365 FWCAVAINSFIAIYLK--RDSIL-RSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQL 1535 +W +++ F+A +K ++I S++F H+ W P ++ LA + Sbjct: 413 WWVILSLTWFLAAGMKWGNEAIAGYSQYF----HLAAWLVPSVKSIAVLALSSVDGDPVA 468 Query: 1536 LFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIV---MVLYEMRN-LRAASGS 1703 C+V G P+ + + T ++ + L+ +R+ ++ G Sbjct: 469 GICYVGNQSLDNLRG--------FVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQDGP 520 Query: 1704 GRFNK----HIRIALFLVVFLGIYAFVFAYRFTITTDQNKWRASLTTYARSAFEGTSQVG 1871 + +K IR+ LF V++ A V A F ++ +W A+ Q Sbjct: 521 TKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDL----QPD 576 Query: 1872 LSSKPSYGLFMAFNFFIGIQG 1934 + +P Y +FM F + G Sbjct: 577 QARRPDYAVFMLKYFMCLVVG 597
>Q61090:FZD7_MOUSE Frizzled-7 precursor - Mus musculus (Mouse)| Length = 572 Score = 43.1 bits (100), Expect = 0.005 Identities = 39/159 (24%), Positives = 69/159 (43%), Gaps = 7/159 (4%) Frame = +3 Query: 1062 EYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTIT 1241 E + A + +G+ LS ST F T L R +P ++F+ C ++A A V Sbjct: 247 ERRFARLWVGVWSVLSCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFL 306 Query: 1242 RGWRKTVCRDHYSPRWGYHEGNGA----CVFNALTVIFGGLGTTFFWCAVAINSFIAIYL 1409 R VC + +S G C + + F G+ ++ +W +++ F+A + Sbjct: 307 LEDR-AVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGM 365 Query: 1410 K--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQI 1517 K ++I S++F H+ W P T+ LA Q+ Sbjct: 366 KWGHEAIEANSQYF----HLAAWAVPAVKTITILAMGQV 400
>Q498S8:FZD8_RAT Frizzled-8 precursor - Rattus norvegicus (Rat)| Length = 684 Score = 42.7 bits (99), Expect = 0.006 Identities = 74/382 (19%), Positives = 136/382 (35%), Gaps = 62/382 (16%) Frame = +3 Query: 975 CYFPWVNASDKDPNFY----------CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTF 1124 C P V+ S + Y CAL C + F + E +G+ L ++STF Sbjct: 230 CRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTF 289 Query: 1125 FVFATMLC-MPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWRKTVC------------ 1265 +T L M R++ +P ++F+ C ++ ++ + G K C Sbjct: 290 ATVSTFLIDMERFK-YPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGG 348 Query: 1266 ---------------RDHYSPRWGYHE-------------GNGACVFNALTVIFGGLGTT 1361 R Y E G C L V F G+ ++ Sbjct: 349 AGGAATAGAGAAGAGASSPGARGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASS 408 Query: 1362 FFWCAVAINSFIAIYLK--RDSIL-RSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQ 1532 +W +++ F+A +K ++I S++F H+ W P ++ LA + Sbjct: 409 IWWVILSLTWFLAAGMKWGNEAIAGYSQYF----HLAAWLVPSVKSIAVLALSSVDGDPV 464 Query: 1533 LLFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIV---MVLYEMRN-LRAASG 1700 C+V G P+ + + T ++ + L+ +R+ ++ G Sbjct: 465 AGICYVGNQSLDNLRG--------FVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQGG 516 Query: 1701 SGRFNK----HIRIALFLVVFLGIYAFVFAYRFTITTDQNKWRASLTTYARSAFEGTSQV 1868 + +K IR+ LF V++ A V A F ++ +W A+ Q Sbjct: 517 PTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDL----QP 572 Query: 1869 GLSSKPSYGLFMAFNFFIGIQG 1934 + +P Y +FM F + G Sbjct: 573 DQARRPDYAVFMLKYFMCLVVG 594
>O57329:FZD7_CHICK Frizzled-7 precursor - Gallus gallus (Chicken)| Length = 567 Score = 42.0 bits (97), Expect = 0.011 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 7/159 (4%) Frame = +3 Query: 1062 EYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTIT 1241 E + A + +G+ L ST F T L R +P ++F+ C ++A A+ Sbjct: 243 EVRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAYAAGFL 302 Query: 1242 RGWRKTVCRDHYSPRWGYHEGNGA----CVFNALTVIFGGLGTTFFWCAVAINSFIAIYL 1409 R VC + +S G C + + F G+ ++ +W +++ F+A + Sbjct: 303 LEER-VVCLERFSEDGYRTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLAAGM 361 Query: 1410 K--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQI 1517 K ++I S++F H+ W P T+ LA Q+ Sbjct: 362 KWGHEAIEANSQYF----HLAAWAVPAVKTITILAMGQV 396
>O75084:FZD7_HUMAN Frizzled-7 precursor - Homo sapiens (Human)| Length = 574 Score = 41.2 bits (95), Expect = 0.018 Identities = 38/159 (23%), Positives = 68/159 (42%), Gaps = 7/159 (4%) Frame = +3 Query: 1062 EYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTIT 1241 E + A + +G+ L ST F T L R +P ++F+ C ++A A V Sbjct: 249 ERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFL 308 Query: 1242 RGWRKTVCRDHYSPRWGYHEGNGA----CVFNALTVIFGGLGTTFFWCAVAINSFIAIYL 1409 R VC + +S G C + + F G+ ++ +W +++ F+A + Sbjct: 309 LEDR-AVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGM 367 Query: 1410 K--RDSI-LRSRWFEIGTHVICWGTPFTCTLIALAAQQI 1517 K ++I S++F H+ W P T+ LA Q+ Sbjct: 368 KWGHEAIEANSQYF----HLAAWAVPAVKTITILAMGQV 402
>Q9VVX3:FRIZ2_DROME Frizzled-2 precursor - Drosophila melanogaster (Fruit fly)| Length = 694 Score = 40.8 bits (94), Expect = 0.024 Identities = 65/331 (19%), Positives = 134/331 (40%), Gaps = 10/331 (3%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFC 1202 C + C F +N E A + + + L + ST T + +P ++F+ C Sbjct: 300 CGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSAC 359 Query: 1203 SHILAFAFVFTITRGWRKTVCRDHYSPRWGYHEGNGACVFNALTVIFGGLGTTFFWCAVA 1382 ++A ++ + C D R G +C L F G+ ++ +W ++ Sbjct: 360 YFMVAVGYLSRNFLQNEEIAC-DGLLLRES-STGPHSCTLVFLLTYFFGMASSIWWVILS 417 Query: 1383 INSFIAIYLK--RDSILR-SRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFCFVT 1553 F+A LK ++I + S++F H+ W P ++ L + L C+V Sbjct: 418 FTWFLAAGLKWGNEAITKHSQYF----HLAAWLIPTVQSVAVLLLSAVDGDPILGICYVG 473 Query: 1554 E-DPYHPKDGKAFSWQYPLFFGPIGFCIVVATGAIV---MVLYEMRN-LRAASGSGRFNK 1718 +P H K P+ +V+ T ++ + L+ +R+ ++ G G K Sbjct: 474 NLNPDHLK---------TFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVK 524 Query: 1719 HIRIALFLVVFLGIYAFVFAYRFTITTDQNKWRAS-LTTYARSAFEGTSQV-GLSSKPSY 1892 ++ L++ +GI++ ++ TI + A+ + ++ +QV G KP Y Sbjct: 525 ADKLEK-LMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLY 583 Query: 1893 GLFMAFNFFIGIQGALVSILFGSNTDVLTFW 1985 + M +F+ + + S ++ + L W Sbjct: 584 SVLM-LKYFMALAVGITSGVWIWSGKTLESW 613
>Q9PTW1:FZD6_CHICK Frizzled-6 - Gallus gallus (Chicken)| Length = 190 Score = 38.9 bits (89), Expect = 0.090 Identities = 20/81 (24%), Positives = 36/81 (44%) Frame = +3 Query: 1023 CALRCPSAFRTNFEYKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFC 1202 CA CP+ + N+E A+ +GI+ +T F F T L + +P +++ C Sbjct: 69 CAPPCPNMYFKNYELDVAKSFIGIVSIFCLCATLFTFLTFLIDVKRFRYPERPIIYYSVC 128 Query: 1203 SHILAFAFVFTITRGWRKTVC 1265 I++ + G +T C Sbjct: 129 YSIVSLMYFIGFLLG-NRTAC 148
>P35352:CAR3_DICDI Cyclic AMP receptor 3 - Dictyostelium discoideum (Slime mold)| Length = 490 Score = 38.9 bits (89), Expect = 0.090 Identities = 53/225 (23%), Positives = 84/225 (37%), Gaps = 8/225 (3%) Frame = +3 Query: 1185 LFVLFCSHILAFAFVFTITRGWRKTVCRDHYSPRWGYHEGNGACVFNALTVIFGGLGTTF 1364 + FCS LA + TI T+ S G+ C A + +G L + Sbjct: 58 IITFFCSTSLAKDLISTIL-----TLIEKKQS------NGSFQCYLYATVITYGSLAC-W 105 Query: 1365 FWCAVAINSFIAIYLKRDSILRSRWFEIGTHVICWGTPFTCTLIALAAQQIGTPNQLLFC 1544 W S + +KR+ FE HV CW PF ++I L+ I +C Sbjct: 106 LWTLCLSFSIYNLIVKREP--EPEKFEKYYHVFCWVVPFIMSVIMLSKGVIEVTGN--WC 161 Query: 1545 FVTEDPYHPKDGKAF-SWQYPLFFGP---IGFCIVVATGAIVMVLYEMRNLRAASGSGR- 1709 ++ G + +++ LF+GP I F V G Y++ + R Sbjct: 162 WI---------GNTYVGYRFGLFYGPFLAIWFLAAVLVGLTSRYTYKVIRSSVSDNKDRH 212 Query: 1710 FNKHIRIALFLVVFLGIYAFVFAYRFTITTDQN---KWRASLTTY 1835 ++ +++VFL +VFA I N W + L TY Sbjct: 213 MTYQFKLINYIIVFL--LCWVFAVINRIVNGLNMFPAWVSILHTY 255
>P13773:CAR1_DICDI Cyclic AMP receptor 1 - Dictyostelium discoideum (Slime mold)| Length = 392 Score = 38.5 bits (88), Expect = 0.12 Identities = 35/168 (20%), Positives = 69/168 (41%), Gaps = 7/168 (4%) Frame = +3 Query: 1302 GNGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLKRDSILRSRWFEIGTHVICWGTPF 1481 G C A+ + +G + +AI+ ++ I + R FE +++CWG P Sbjct: 75 GGFPCYLYAIVITYGSFACWLWTLCLAISIYMLIVKREPEPER---FEKYYYLLCWGLPL 131 Query: 1482 TCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFS-WQYPLFFGPIGFCIVVATGAIV 1658 T++ LA + +C++ G +F+ +++ LF+GP F + A A++ Sbjct: 132 ISTIVMLAKNTVQFVGN--WCWI---------GVSFTGYRFGLFYGP--FLFIWAISAVL 178 Query: 1659 MVLYEMRNLRAASGSGRFNK------HIRIALFLVVFLGIYAFVFAYR 1784 + L NK ++ +++VFL + F R Sbjct: 179 VGLTSRYTYVVIHNGVSDNKEKHLTYQFKLINYIIVFLVCWVFAVVNR 226
>Q5UAW9:GP157_HUMAN Probable G-protein coupled receptor 157 - Homo sapiens (Human)| Length = 335 Score = 36.6 bits (83), Expect = 0.45 Identities = 31/141 (21%), Positives = 55/141 (39%), Gaps = 2/141 (1%) Frame = +3 Query: 1104 LSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWRKTVCRDHYSP 1283 LS + + + AT P R L+LF+ + A ++ + + + + P Sbjct: 24 LSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQNFA--------GP 75 Query: 1284 RWGYHEGNGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLKRDSILRSR--WFEIGTH 1457 W CV F + F+ A+A+ +++I R W H Sbjct: 76 SWD-------CVLQGALSTFANTSSFFWTVAIALYLYLSIVRAARGPRTDRLLW---AFH 125 Query: 1458 VICWGTPFTCTLIALAAQQIG 1520 V+ WG P T+ A+A ++IG Sbjct: 126 VVSWGVPLVITVAAVALKKIG 146
>O00421:CCRL2_HUMAN C-C chemokine receptor-like 2 - Homo sapiens (Human)| Length = 344 Score = 33.9 bits (76), Expect = 2.9 Identities = 36/164 (21%), Positives = 60/164 (36%), Gaps = 2/164 (1%) Frame = +3 Query: 1281 PRWGYHEGNGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLKRDSILRSRWFEIG--T 1454 P W + G+ C G TFF C + + ++ K + R G T Sbjct: 92 PFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIIT 151 Query: 1455 HVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCI 1634 V+ W T TL + +Q C + P+ P D + F W++ L + + Sbjct: 152 SVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPAD-ETF-WKHFLTL-KMNISV 208 Query: 1635 VVATGAIVMVLYEMRNLRAASGSGRFNKHIRIALFLVVFLGIYA 1766 +V I LY R++ + +VVFL ++A Sbjct: 209 LVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWA 252
>O19906:GLTB_CYACA Ferredoxin-dependent glutamate synthase - Cyanidium caldarium| Length = 1549 Score = 33.5 bits (75), Expect = 3.8 Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 15/123 (12%) Frame = +3 Query: 144 NYTNGNTLGLPQFNPLLGVANAGCPAADNVFLNTTATAVAPNNSYVQEIVNFFPYCRPML 323 N +N ++ L L CP A +FL A P Y Q +++F+ YC Sbjct: 305 NVSNSDSANLDSVVELFLHVGHSCPEA-LMFLIPEAYENNPKLKYHQNLISFYEYCAGFQ 363 Query: 324 DQWNAAGKLIVFP-------------TKPQAFDATWEGV--KASLIGTLNSAYSLVRTLG 458 + W+ LIVF +P + T + V AS G LN SL+R G Sbjct: 364 EAWDGPA-LIVFSDGHTVGASLDRNGLRPARYCVTEDNVLILASEGGVLNLDPSLIRLKG 422 Query: 459 HSG 467 G Sbjct: 423 RLG 425
>P41586:PACR_HUMAN Pituitary adenylate cyclase-activating polypeptide type I receptor| precursor - Homo sapiens (Human) Length = 468 Score = 33.1 bits (74), Expect = 5.0 Identities = 52/234 (22%), Positives = 88/234 (37%), Gaps = 5/234 (2%) Frame = +3 Query: 1095 IGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWRKTVCRDH 1274 +G+ + + T +LC R H N + LF S +L VF + W +D Sbjct: 159 VGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFI--KDWILYAEQDS 216 Query: 1275 YSPRWGYHEGNGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLKRDSILRSRWFEIGT 1454 E VF V+ + +FW + I L ++ R + Sbjct: 217 NHCFISTVECKAVMVFFHYCVV-----SNYFW--LFIEGLYLFTLLVETFFPERRYFYWY 269 Query: 1455 HVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSW--QYPLFFGPIGF 1628 +I WGTP C + L F + D A W + P+ G I Sbjct: 270 TIIGWGTPTVCVTVWAT---------LRLYFDDTGCWDMNDSTALWWVIKGPV-VGSIMV 319 Query: 1629 CIVVATGAIVMVLYEMRNLRAASGSGRFNKHIRIA---LFLVVFLGIYAFVFAY 1781 V+ G IV+++ ++++ G + ++R+A L L+ GI+ VFA+ Sbjct: 320 NFVLFIGIIVILVQKLQS--PDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAF 371
>Q5FVG1:GP157_RAT Probable G-protein coupled receptor 157 - Rattus norvegicus (Rat)| Length = 330 Score = 32.7 bits (73), Expect = 6.5 Identities = 35/160 (21%), Positives = 63/160 (39%), Gaps = 8/160 (5%) Frame = +3 Query: 1065 YKQAEIMMGIIGWLSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTITR 1244 +++A +++ + LS + + + AT P R L+LF+ + A ++ + Sbjct: 13 WERAVVLLSCV--LSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYG--- 67 Query: 1245 GWRKTVCRDHYSPRWGYHEGNGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLKRDSI 1424 V +D W CV F ++FFW IA+YL + + Sbjct: 68 -----VLQDFAGTSWD-------CVLQGALSTFANT-SSFFWTVA-----IALYLYLNIV 109 Query: 1425 LRSR--------WFEIGTHVICWGTPFTCTLIALAAQQIG 1520 +R W H+I WG P T+ A+ ++IG Sbjct: 110 RATRGPCTDHLVW---AFHLISWGVPLAITVAAVCLKKIG 146
>Q8C206:GP157_MOUSE Probable G-protein coupled receptor 157 - Mus musculus (Mouse)| Length = 330 Score = 32.7 bits (73), Expect = 6.5 Identities = 31/141 (21%), Positives = 55/141 (39%), Gaps = 2/141 (1%) Frame = +3 Query: 1104 LSYISTFFVFATMLCMPRYRHFPANLVLFVLFCSHILAFAFVFTITRGWRKTVCRDHYSP 1283 LS + + + AT P R L+LF+ + A ++ + V +D Sbjct: 24 LSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYG--------VLQDFAGT 75 Query: 1284 RWGYHEGNGACVFNALTVIFGGLGTTFFWCAVAINSFIAIY--LKRDSILRSRWFEIGTH 1457 W CV F + F+ A+A+ +++I + S W H Sbjct: 76 SWD-------CVLQGALSTFANTSSFFWTVAIALYLYLSIVRTTRGPSTDHLIW---AFH 125 Query: 1458 VICWGTPFTCTLIALAAQQIG 1520 +I WG P T+ A++ ++IG Sbjct: 126 LISWGVPLAITVAAVSLKKIG 146
>Q11NY7:DXS_CYTH3 1-deoxy-D-xylulose-5-phosphate synthase - Cytophaga hutchinsonii| (strain ATCC 33406 / NCIMB 9469) Length = 636 Score = 32.7 bits (73), Expect = 6.5 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Frame = +3 Query: 231 VFLNTTATAVAPN----NSYVQEIVNFFPYCRPMLDQWNAAGKLIVFPTKPQAFDATWE- 395 + LN A+ PN Y+ +I Y R + WN GK+ F QA + E Sbjct: 173 IVLNDNCMAIDPNVGALKDYLVDITTSRTYNRVRDEVWNMLGKISKFGPNAQAIASKVES 232 Query: 396 GVKASLIGTLNSAYSL 443 G+KASL+ N SL Sbjct: 233 GLKASLLKQSNLFESL 248
>Q9XSD7:CCRL2_MACMU C-C chemokine receptor-like 2 - Macaca mulatta (Rhesus macaque)| Length = 344 Score = 32.7 bits (73), Expect = 6.5 Identities = 36/164 (21%), Positives = 62/164 (37%), Gaps = 2/164 (1%) Frame = +3 Query: 1281 PRWGYHEGNGACVFNALTVIFGGLGTTFFWCAVAINSFIAIYLKRD--SILRSRWFEIGT 1454 P W + G+ C G TFF C + + ++ K + S+ R I T Sbjct: 92 PFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTLQRYLVFLHKGNFFSVRRRVPCGIVT 151 Query: 1455 HVICWGTPFTCTLIALAAQQIGTPNQLLFCFVTEDPYHPKDGKAFSWQYPLFFGPIGFCI 1634 + W T T+ A + + C + P+ P D + F W++ L + + Sbjct: 152 SAVAWVTAILATVPEFAVYKPQMEDPKYKCAFSRTPFLPAD-ETF-WKHFLTL-KMNVSV 208 Query: 1635 VVATGAIVMVLYEMRNLRAASGSGRFNKHIRIALFLVVFLGIYA 1766 +V I LY G R++ + +VVFL ++A Sbjct: 209 LVFPLFIFTFLYVQMRKTLRFGEQRYSLFKLVFAIMVVFLLMWA 252
>Q6PRD1:GP179_HUMAN Probable G-protein coupled receptor 179 precursor - Homo sapiens| (Human) Length = 2367 Score = 32.3 bits (72), Expect = 8.5 Identities = 16/38 (42%), Positives = 22/38 (57%) Frame = +2 Query: 815 RLEQPHLRPTSLPPRLSELRSVEDSYCSADHHQHDRRR 928 RLE+P P S PP ++ SV+ S+ S H+ RRR Sbjct: 890 RLERPRGAPLSAPPSPAKSSSVDSSHTSGRLHEEARRR 927
>Q8BTI8:SRRM2_MOUSE Serine/arginine repetitive matrix protein 2 - Mus musculus (Mouse)| Length = 2703 Score = 32.3 bits (72), Expect = 8.5 Identities = 21/44 (47%), Positives = 22/44 (50%) Frame = -1 Query: 1047 RQRGNAGRSRSWGPCRRRSPTGSSTATDRSAGRQKCSRQGRRRS 916 R GRSRS P RRRS T S RS R + R GR RS Sbjct: 604 RTPARRGRSRSRTPTRRRSRT-RSPVRRRSRSRSQARRSGRSRS 646
>Q9UQ35:SRRM2_HUMAN Serine/arginine repetitive matrix protein 2 - Homo sapiens (Human)| Length = 2752 Score = 32.3 bits (72), Expect = 8.5 Identities = 18/44 (40%), Positives = 21/44 (47%) Frame = -1 Query: 1047 RQRGNAGRSRSWGPCRRRSPTGSSTATDRSAGRQKCSRQGRRRS 916 R GRSRS P RR + S T R R + R+GR RS Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRS 704
>Q9HC84:MUC5B_HUMAN Mucin-5B precursor - Homo sapiens (Human)| Length = 5703 Score = 32.3 bits (72), Expect = 8.5 Identities = 20/64 (31%), Positives = 29/64 (45%) Frame = +1 Query: 142 LTTPTATPSACHSSTRSLALPTLAAPRRITFSLIRPQRRLPLITATCRRSLTSSPTAVPC 321 LT+P TP+A S S + P R LP++T+T +S +S T +P Sbjct: 4224 LTSPATTPTATSSKATSSSSP-------------RTATTLPVLTSTATKSTATSVTPIPS 4270 Query: 322 LTSG 333 T G Sbjct: 4271 STLG 4274 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 310,183,455 Number of extensions: 6544386 Number of successful extensions: 22703 Number of sequences better than 10.0: 52 Number of HSP's gapped: 22623 Number of HSP's successfully gapped: 52 Length of query: 737 Length of database: 100,686,439 Length adjustment: 121 Effective length of query: 616 Effective length of database: 67,496,744 Effective search space: 41577994304 Effective search space used: 41577994304 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
