ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf27m04 |
|---|---|
| Clone Library Name | barley_pub |
>Q94A68:Y1669_ARATH Putative oxidoreductase At1g06690, chloroplast precursor -| Arabidopsis thaliana (Mouse-ear cress) Length = 377 Score = 533 bits (1374), Expect = e-151 Identities = 256/340 (75%), Positives = 298/340 (87%), Gaps = 2/340 (0%) Frame = +2 Query: 167 SEGAAVEDGSKAMLGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDS 346 S A+ + SK LG S + VTKLGIG WSWGD +YWNDFQWDDRKLK AKGAFD S+D+ Sbjct: 38 SVAPAISEESKVKLGGSDLKVTKLGIGVWSWGDNSYWNDFQWDDRKLKAAKGAFDTSLDN 97 Query: 347 GITFFDTAEVYGAGVS-GAINSESLLGRFIKERQEKEK-VDVAIATKFAALPWRFGRGSV 520 GI FFDTAEVYG+ S GAI+SE+LLGRFI+ER+E+ +V++ATKFAALPWRFGR SV Sbjct: 98 GIDFFDTAEVYGSKFSLGAISSETLLGRFIRERKERYPGAEVSVATKFAALPWRFGRESV 157 Query: 521 ISALKGSLSRLGVSSVESYQLHWPGIWGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRD 700 ++ALK SLSRL +SSV+ YQLHWPG+WGNEGYLDGL DA EQGLVK+VGVSNYSEKRLRD Sbjct: 158 VTALKDSLSRLELSSVDLYQLHWPGLWGNEGYLDGLGDAVEQGLVKAVGVSNYSEKRLRD 217 Query: 701 AHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPA 880 A++RLKKRG+PLASNQVNYSLIYR PE+ GVKAACDELG+TLIAYSPIAQGALTGKYTP Sbjct: 218 AYERLKKRGIPLASNQVNYSLIYRAPEQTGVKAACDELGVTLIAYSPIAQGALTGKYTPE 277 Query: 881 NPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNA 1060 NPP+GPRGRIYT +FL+KLQPL+N+I+ IG +Y KTPTQ+ LNWL+ QGNV+PIPGAKNA Sbjct: 278 NPPSGPRGRIYTREFLTKLQPLLNRIKQIGENYSKTPTQIALNWLVAQGNVIPIPGAKNA 337 Query: 1061 EQAREFAGALGWLLTEQEVEELRSMAREVKPVMGFPVEKL 1180 EQA+EFAGA+GW LT+ EV ELRS+A E+KPV+GFPVE L Sbjct: 338 EQAKEFAGAIGWSLTDNEVSELRSLASEIKPVVGFPVEYL 377
>P63485:Y2320_MYCBO Uncharacterized oxidoreductase Mb2320 - Mycobacterium bovis| Length = 323 Score = 137 bits (344), Expect = 1e-31 Identities = 105/315 (33%), Positives = 161/315 (51%), Gaps = 5/315 (1%) Frame = +2 Query: 227 VTKLGIGAWSWGDTTYWNDFQWDDRKLKDA-KGAFDASVDSGITFFDTAEVYGAGVSGAI 403 V+++G+G W +G ++ + DR A + + G+T FDTAE+YG G Sbjct: 12 VSRIGLGTWQFGS----REWGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLG----- 62 Query: 404 NSESLLGRFIKERQEKEKVDVAIATK-FAALPWRFGRGSVISALKGSLSRLGVSSVESYQ 580 SE +LG + + ++ +V +A+K F P+ + + + S RL ++ + YQ Sbjct: 63 KSERILGEALGD----DRTEVVVASKVFPVAPFP---AVIKNRERASARRLQLNRIPLYQ 115 Query: 581 LHWPG-IWGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNY 757 +H P + + + G+ D + G + + GVSNYS R R A L G P+ SNQV++ Sbjct: 116 IHQPNPVVPDSVIMPGMRDLLDSGDIGAAGVSNYSLARWRKADAAL---GRPVVSNQVHF 172 Query: 758 SLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGR--IYTSDFLS 931 SL + + E+ V A E I +IAYSP+AQG L GKY N P G R ++ ++ L Sbjct: 173 SLAHPDALEDLVPFAELENRI-VIAYSPLAQGLLGGKYGLENRPGGVRALNPLFGTENLR 231 Query: 932 KLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQ 1111 +++PL+ +R I D P QV L WLI VV IPGA + EQ A L+ Q Sbjct: 232 RIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNVAAADIELSAQ 291 Query: 1112 EVEELRSMAREVKPV 1156 + L AR +PV Sbjct: 292 SRDALTDAARAFRPV 306
>P63484:Y2298_MYCTU Uncharacterized oxidoreductase Rv2298/MT2355 - Mycobacterium| tuberculosis Length = 323 Score = 137 bits (344), Expect = 1e-31 Identities = 105/315 (33%), Positives = 161/315 (51%), Gaps = 5/315 (1%) Frame = +2 Query: 227 VTKLGIGAWSWGDTTYWNDFQWDDRKLKDA-KGAFDASVDSGITFFDTAEVYGAGVSGAI 403 V+++G+G W +G ++ + DR A + + G+T FDTAE+YG G Sbjct: 12 VSRIGLGTWQFGS----REWGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLG----- 62 Query: 404 NSESLLGRFIKERQEKEKVDVAIATK-FAALPWRFGRGSVISALKGSLSRLGVSSVESYQ 580 SE +LG + + ++ +V +A+K F P+ + + + S RL ++ + YQ Sbjct: 63 KSERILGEALGD----DRTEVVVASKVFPVAPFP---AVIKNRERASARRLQLNRIPLYQ 115 Query: 581 LHWPG-IWGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNY 757 +H P + + + G+ D + G + + GVSNYS R R A L G P+ SNQV++ Sbjct: 116 IHQPNPVVPDSVIMPGMRDLLDSGDIGAAGVSNYSLARWRKADAAL---GRPVVSNQVHF 172 Query: 758 SLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGR--IYTSDFLS 931 SL + + E+ V A E I +IAYSP+AQG L GKY N P G R ++ ++ L Sbjct: 173 SLAHPDALEDLVPFAELENRI-VIAYSPLAQGLLGGKYGLENRPGGVRALNPLFGTENLR 231 Query: 932 KLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQ 1111 +++PL+ +R I D P QV L WLI VV IPGA + EQ A L+ Q Sbjct: 232 RIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNVAAADIELSAQ 291 Query: 1112 EVEELRSMAREVKPV 1156 + L AR +PV Sbjct: 292 SRDALTDAARAFRPV 306
>P80874:GS69_BACSU General stress protein 69 - Bacillus subtilis| Length = 331 Score = 109 bits (273), Expect = 2e-23 Identities = 83/321 (25%), Positives = 153/321 (47%), Gaps = 14/321 (4%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVS 394 +G+ +++G+G W+ G T W K + A++D GIT DTA YG G Sbjct: 9 TGIEASRIGLGTWAIGGT------MWGGTDEKTSIETIRAALDQGITLIDTAPAYGFG-- 60 Query: 395 GAINSESLLGRFIKERQEKEKVDVAIATKFAALPWR-------FGRGSVISALKGSLSRL 553 SE ++G+ IKE ++++V +A T AL W+ R ++ ++ SL RL Sbjct: 61 ---QSEEIVGKAIKEYGKRDQVILATKT---ALDWKNNQLFRHANRARIVEEVENSLKRL 114 Query: 554 GVSSVESYQLHWPG-IWGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGV 730 ++ YQ+HWP + E + + + Y+ G ++++GVSN+S +++ + Sbjct: 115 QTDYIDLYQVHWPDPLVPIEETAEVMKELYDAGKIRAIGVSNFSIEQMDTF-----RAVA 169 Query: 731 PLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRI 910 PL + Q Y+L R EE+ + A D IT + Y + +G LTGK T G R Sbjct: 170 PLHTIQPPYNLFEREMEESVLPYAKDN-KITTLLYGSLCRGLLTGKMTEEYTFEGDDLRN 228 Query: 911 YTSDF----LSKLQPLINKI-RVIGGSYDKTPTQVVLNWLICQ-GNVVPIPGAKNAEQAR 1072 + F + +N++ ++ Y K+ + + W++ Q G + + GA+ Q Sbjct: 229 HDPKFQKPRFKEYLSAVNQLDKLAKTRYGKSVIHLAVRWILDQPGADIALWGARKPGQLE 288 Query: 1073 EFAGALGWLLTEQEVEELRSM 1135 + GW L ++ +++ ++ Sbjct: 289 ALSEITGWTLNSEDQKDINTI 309
>Q09923:YAKC_SCHPO Aldo-keto reductase yakc [NADP+] - Schizosaccharomyces pombe (Fission| yeast) Length = 340 Score = 109 bits (272), Expect = 3e-23 Identities = 87/281 (30%), Positives = 139/281 (49%), Gaps = 16/281 (5%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFA--------A 490 + D G TF+D++++YG G + E +GR+ K+ ++ ++ +ATKF Sbjct: 42 AADLGCTFWDSSDMYGFGAN-----EECIGRWFKQTGRRK--EIFLATKFGYEKNPETGE 94 Query: 491 LPWRFGRGSVISALKGSLSRLGVSSVESYQLH-WPGIWGNEGYLDGLADAYEQGLVKSVG 667 L + AL SL RLG+ ++ Y +H + G E + L E G ++ +G Sbjct: 95 LSLNNEPDYIEKALDLSLKRLGIDCIDLYYVHRFSGETPIEKIMGALKKCVEAGKIRYIG 154 Query: 668 VSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPE--ENGVKAACDELGITLIAYSP 841 +S S +R A P+++ QV YS E E GV AC E IT++ Y+P Sbjct: 155 LSECSANTIRRA-----AAVYPVSAVQVEYSPFSLEIERPEIGVMKACRENNITIVCYAP 209 Query: 842 IAQGALTGKY-TPANPPTGP---RGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLN 1009 + +G LTG Y +P + P G + Y + K L+ KI I + + TP Q+ L Sbjct: 210 LGRGFLTGAYKSPDDFPEGDFRRKAPRYQKENFYKNLELVTKIEKIATANNITPGQLSLA 269 Query: 1010 WLICQG-NVVPIPGAKNAEQAREFAGALGWLLTEQEVEELR 1129 WL+ QG +++PIPG K + E GAL L++ V+E+R Sbjct: 270 WLLAQGDDILPIPGTKRVKYLEENFGALKVKLSDATVKEIR 310
>P77735:YAJO_ECOLI Uncharacterized oxidoreductase yajO - Escherichia coli| Length = 324 Score = 107 bits (266), Expect = 2e-22 Identities = 91/329 (27%), Positives = 155/329 (47%), Gaps = 9/329 (2%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG + + V++L +G ++G+ N W + + ++ +++ GI FFDTA Y Sbjct: 6 LGKTDLRVSRLCLGCMTFGEPDRGNH-AWTLPE-ESSRPIIKRALEGGINFFDTANSYSD 63 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF----AALPWRFGRGSVISALKGSLSRL 553 G +SE ++GR +++ +E DV +ATK LP R ++ ++ SL RL Sbjct: 64 G-----SSEEIVGRALRDFARRE--DVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRL 116 Query: 554 GVSSVESYQLH-WPGIWGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRG- 727 G+ V+ Q+H W E L+ L D + G + +G S+ + A + K+ G Sbjct: 117 GMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQFAQALELQKQHGW 176 Query: 728 VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKY--TPANPPTGPR 901 S Q +Y+LIYR EE + C + G+ +I +SP+A+G LT + T A + Sbjct: 177 AQFVSMQDHYNLIYRE-EEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEV 235 Query: 902 GRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQ-GNVVPIPGAKNAEQAREF 1078 G+ + + ++ + T QV L WL+ + G PI G EQ E Sbjct: 236 GKNLYKESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDEL 295 Query: 1079 AGALGWLLTEQEVEELRSMAREVKPVMGF 1165 A+ L +++ EL + + PV+GF Sbjct: 296 LNAVDITLKPEQIAELETPYKP-HPVVGF 323
>P15339:DKGB_CORSS 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain| SHS752001) Length = 277 Score = 101 bits (251), Expect = 8e-21 Identities = 86/281 (30%), Positives = 136/281 (48%), Gaps = 8/281 (2%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWR 502 A A++DSG DTA Y +ES +GR ++ ++ ++ +A+K +P R Sbjct: 33 AMVAAIDSGYRLLDTAVNY--------ENESEVGRAVRA-SSVDRDELIVASK---IPGR 80 Query: 503 -FGRGSVISALKGSLSRLGVSSVESYQLHWP----GIWGNEGYLD---GLADAYEQGLVK 658 GR + +++GSL RLG+ ++ +HWP G W LD G+ DA E GLV+ Sbjct: 81 QHGRAEAVDSIRGSLDRLGLDVIDLQLIHWPNPSVGRW-----LDTWRGMIDAREAGLVR 135 Query: 659 SVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYS 838 S+GVSN++E L+ D + GV A NQV + + ++A DE GI ++S Sbjct: 136 SIGVSNFTEPMLKTLID---ETGVTPAVNQVELHPYF---PQAALRAFHDEHGIRTESWS 189 Query: 839 PIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLI 1018 P+A+ R + T L +L + Y TPTQVVL W + Sbjct: 190 PLAR----------------RSELLTEQLLQELAVV----------YGVTPTQVVLRWHV 223 Query: 1019 CQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAR 1141 G+ PIP + + ++ RE A G+ LT +V+ + + R Sbjct: 224 QLGS-TPIPKSADPDRQRENADVFGFALTADQVDAISGLER 263
>P46905:YCCK_BACSU Uncharacterized oxidoreductase yccK - Bacillus subtilis| Length = 310 Score = 95.9 bits (237), Expect = 3e-19 Identities = 89/315 (28%), Positives = 150/315 (47%), Gaps = 11/315 (3%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG + + V ++G GA + G + + +D KD ++D G+ F DTA +YG Sbjct: 7 LGKTKLKVKRIGFGANAVGGHNLFPNL--NDETGKDL---VRTALDGGVNFIDTAFIYGL 61 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKFA------ALPWRFGRGSVISALKGSLS 547 G SE L+G ++ER + ++ IATK A ++ R + S ++ SL Sbjct: 62 G-----RSEELIGEVVQERGVRN--ELIIATKGAHKEVDGSIELDNSREFLRSEVEKSLK 114 Query: 548 RLGVSSVESYQLHWPGIWGNEGYLDG-LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKR 724 RL ++ Y +H+P + G L + ++G +K++G SN ++L+D + Sbjct: 115 RLKTDYIDLYYVHFPDGKTPLAEVAGTLKELKDEGKIKAIGASNLDYQQLQDFN-----A 169 Query: 725 GVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTP---ANPPTG 895 L Q YSLI R+ E+ + C++ GI+ I Y P+A G LTGK+T + Sbjct: 170 DGYLEVFQAEYSLIQRDAEKE-LLPYCEKQGISFIPYFPLASGLLTGKFTQDTVFDDFRK 228 Query: 896 PRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNV-VPIPGAKNAEQAR 1072 + + F+ L+ ++K++ + V L WL+ + + IPGAK EQ + Sbjct: 229 DKPQFQGETFIHNLKK-VDKLKAVAEEKQADTAHVALAWLLTRPAIDAIIPGAKRPEQLQ 287 Query: 1073 EFAGALGWLLTEQEV 1117 + L LTE EV Sbjct: 288 DNLKTLNIELTEDEV 302
>Q46851:YGHZ_ECOLI Uncharacterized protein yghZ - Escherichia coli| Length = 346 Score = 94.4 bits (233), Expect = 1e-18 Identities = 87/314 (27%), Positives = 146/314 (46%), Gaps = 20/314 (6%) Frame = +2 Query: 209 GASGVAVTKLGIGAW-SWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 G SG+ + L +G W ++G L+ + + D GIT FD A YG Sbjct: 19 GKSGLRLPALSLGLWHNFGHVN----------ALESQRAILRKAFDLGITHFDLANNYGP 68 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATK--FAALPWRFGRGS----VISALKGSLS 547 A E GR ++E + ++ I+TK + P +G G ++++L SL Sbjct: 69 PPGSA---EENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLK 125 Query: 548 RLGVSSVESYQLHWPGIWGN---EGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLK 718 R+G+ V+ + H + N E LA A + G VG+S+YS +R + + L+ Sbjct: 126 RMGLEYVDIFYSH--RVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVELLR 183 Query: 719 KRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPP--- 889 + +PL +Q +Y+L+ R +++G+ G+ IA++P+AQG LTGKY P Sbjct: 184 EWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQDSR 243 Query: 890 ---TGPRGRIYTSDFLSKLQPLINKIRVI---GGSYDKTPTQVVLNWLICQGNVVPI-PG 1048 G + R T L++ +N +R++ ++ Q+ L+WL+ V + G Sbjct: 244 MHREGNKVRGLTPKMLTEAN--LNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSVLIG 301 Query: 1049 AKNAEQAREFAGAL 1090 A AEQ E AL Sbjct: 302 ASRAEQLEENVQAL 315
>Q8X529:YGHZ_ECO57 Uncharacterized protein yghZ - Escherichia coli O157:H7| Length = 346 Score = 93.6 bits (231), Expect = 2e-18 Identities = 89/322 (27%), Positives = 147/322 (45%), Gaps = 20/322 (6%) Frame = +2 Query: 209 GASGVAVTKLGIGAW-SWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 G SG+ + L +G W ++G L+ + + D GIT FD A YG Sbjct: 19 GKSGLRLPALSLGLWHNFGHVN----------ALESQRAILRKAFDLGITHFDLANNYGP 68 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATK--FAALPWRFGRGS----VISALKGSLS 547 A E GR ++E + ++ I+TK + P +G G ++++L SL Sbjct: 69 PPGSA---EENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLK 125 Query: 548 RLGVSSVESYQLHWPGIWGN---EGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLK 718 R+G+ V+ + H + N E LA A + G VG+S+YS +R + + L Sbjct: 126 RMGLEYVDIFYSH--RVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVELLH 183 Query: 719 KRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPP--- 889 + +PL +Q +Y+L+ R +++G+ G+ IA++P+AQG LTGKY P Sbjct: 184 EWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPEDSR 243 Query: 890 ---TGPRGRIYTSDFLSKLQPLINKIRVI---GGSYDKTPTQVVLNWLICQGNVVPI-PG 1048 G + R T L++ +N +R++ ++ Q+ L+WL+ V + G Sbjct: 244 MHREGNKVRGLTPKMLTEAN--LNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLVG 301 Query: 1049 AKNAEQAREFAGALGWLLTEQE 1114 A AEQ E AL L E Sbjct: 302 ASRAEQLEENVQALNNLTFSTE 323
>Q40648:KCAB_ORYSJ Probable voltage-gated potassium channel subunit beta - Oryza sativa| subsp. japonica (Rice) Length = 328 Score = 89.7 bits (221), Expect = 2e-17 Identities = 93/337 (27%), Positives = 146/337 (43%), Gaps = 25/337 (7%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V++L GAW T+ N +K+AK A D+G+ FFD AEVY Sbjct: 6 LGRSGLRVSQLSYGAW----VTFGNQLD-----VKEAKALLQACRDAGVNFFDNAEVYAN 56 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWR--------FGRGSVISALKGS 541 G +E ++G+ +++ + DV ++TK L W R ++ L+GS Sbjct: 57 G-----RAEEIMGQAMRDLGWRRS-DVVVSTK---LFWGGQGPNDKGLSRKHIVEGLRGS 107 Query: 542 LSRLGVSSVESYQLHWPGIWGN-EGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAH---D 709 L RL + V+ H P E + + + G+ G S +S +++ +A + Sbjct: 108 LKRLDMDYVDVVYCHRPDATTPVEETVRAMNWVIDHGMAFYWGTSEWSAQQITEAWSVAN 167 Query: 710 RLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPP 889 RL G P+ Q Y+L R+ E+ G+ L +SP+A G LTGKY N P Sbjct: 168 RLDLVG-PIVE-QPEYNLFSRHKVESEFLPLYSTYGLGLTTWSPLASGVLTGKYAKGNIP 225 Query: 890 TGPR----------GRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVP 1039 R R D L K +N ++ I + Q+ + W NV Sbjct: 226 ADSRFALENYKNLANRSLVDDTLRK----VNGLKPIASELGVSLAQLAIAWCASNPNVSS 281 Query: 1040 -IPGAKNAEQAREFAGALGW--LLTEQEVEELRSMAR 1141 I GA Q E AL LLT + V+++ ++ + Sbjct: 282 VITGATKENQIVENMKALDVIPLLTPEVVDKIEAVVQ 318
>P77256:YDJG_ECOLI Uncharacterized oxidoreductase ydjG - Escherichia coli| Length = 326 Score = 87.4 bits (215), Expect = 1e-16 Identities = 84/347 (24%), Positives = 151/347 (43%), Gaps = 29/347 (8%) Frame = +2 Query: 197 KAMLGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDS---GITFFDT 367 K LG + + ++++G+G W+ G WN DR++ D +++ GI DT Sbjct: 3 KIPLGTTDITLSRMGLGTWAIGGGPAWNGDL--DRQI-----CIDTILEAHRCGINLIDT 55 Query: 368 AEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGR------------ 511 A Y G NSE ++G+ +K+ ++ V + TK + R G Sbjct: 56 APGYNFG-----NSEVIVGQALKKLPREQ---VVVETKCGIVWERKGSLFNKVGDRQLYK 107 Query: 512 ----GSVISALKGSLSRLGVSSVESYQLHWPGIWGNEGYLDGLADAY-------EQGLVK 658 S+ + SL RLG+ ++ Y HW + + +A+ +G ++ Sbjct: 108 NLSPESIREEVAASLQRLGIDYIDIYMTHWQSV---PPFFTPIAETVAVLNELKSEGKIR 164 Query: 659 SVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYS 838 ++G +N +R+ + L Q YS++ R EN + C + GI + YS Sbjct: 165 AIGAANVDADHIREYLQYGE-----LDIIQAKYSILDR-AMENELLPLCRDNGIVVQVYS 218 Query: 839 PIAQGALTGKYTPANPPTGPRGR--IYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNW 1012 P+ QG LTG T P G R + + + K+ ++ + + + Y T + L W Sbjct: 219 PLEQGLLTGTITRDYVPGGARANKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAW 278 Query: 1013 LICQGNVVPI-PGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 ++ Q +++ I GA EQ RE AL L++ + +R MA ++ Sbjct: 279 ILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREMAEALE 325
>P46336:IOLS_BACSU Protein iolS - Bacillus subtilis| Length = 310 Score = 84.0 bits (206), Expect = 1e-15 Identities = 82/306 (26%), Positives = 141/306 (46%), Gaps = 16/306 (5%) Frame = +2 Query: 197 KAMLGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEV 376 KA LG S + V +G+G + G + + + K ++ +G+T DTA + Sbjct: 3 KAKLGKSDLQVFPIGLGTNAVGGHNLYPNLNEET-----GKELVREAIRNGVTMLDTAYI 57 Query: 377 YGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVIS--------AL 532 YG G SE L+G ++E + DV IATK A + G V ++ Sbjct: 58 YGIG-----RSEELIGEVLREFNRE---DVVIATKAAHR--KQGNDFVFDNSPDFLKKSV 107 Query: 533 KGSLSRLGVSSVESYQLHWPGIWG-NEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHD 709 SL RL ++ + +H+P + ++ L + + G ++S+GVSN+S ++L++A+ Sbjct: 108 DESLKRLNTDYIDLFYIHFPDEHTPKDEAVNALNEMKKAGKIRSIGVSNFSLEQLKEAN- 166 Query: 710 RLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPP 889 K G+ + Q Y+L+ R E+ E I+ I Y P+ G L GKYT Sbjct: 167 ---KDGL-VDVLQGEYNLLNREAEKTFFPYT-KEHNISFIPYFPLVSGLLAGKYT--EDT 219 Query: 890 TGPRGRI------YTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNV-VPIPG 1048 T P G + + + + +NK+ I ++ +VL W + + + + IPG Sbjct: 220 TFPEGDLRNEQEHFKGERFKENIRKVNKLAPIAEKHNVDIPHIVLAWYLARPEIDILIPG 279 Query: 1049 AKNAEQ 1066 AK A+Q Sbjct: 280 AKRADQ 285
>P62483:KCAB2_RAT Voltage-gated potassium channel subunit beta-2 - Rattus norvegicus| (Rat) Length = 367 Score = 82.8 bits (203), Expect = 3e-15 Identities = 87/328 (26%), Positives = 141/328 (42%), Gaps = 18/328 (5%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ D+ A+ + D+GI FDTAEVY A Sbjct: 42 LGKSGLRVSCLGLGTW----VTFGGQIT-DEM----AEHLMTLAYDNGINLFDTAEVYAA 92 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E +LG IK++ + + I TK A R +I LK SL R Sbjct: 93 G-----KAEVVLGNIIKKKGWRRS-SLVITTKIFWGGKAETERGLSRKHIIEGLKASLER 146 Query: 551 LGVSSVESYQLHWPGI-WGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRG 727 L + V+ + P E + + QG+ G S +S + +A+ ++ Sbjct: 147 LQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFN 206 Query: 728 -VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPP---TG 895 +P Q Y + R E + ++G+ + +SP+A G ++GKY PP Sbjct: 207 LIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRAS 266 Query: 896 PRGRIYTSDFL-----SKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPI-PGAKN 1057 +G + D + + Q + +++ I T Q+ + W + V + GA N Sbjct: 267 LKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASN 326 Query: 1058 AEQAREFAGALGWL--LTEQEVEELRSM 1135 AEQ E GA+ L L+ V E+ S+ Sbjct: 327 AEQLMENIGAIQVLPKLSSSIVHEIDSI 354
>P62482:KCAB2_MOUSE Voltage-gated potassium channel subunit beta-2 - Mus musculus (Mouse)| Length = 367 Score = 82.8 bits (203), Expect = 3e-15 Identities = 87/328 (26%), Positives = 141/328 (42%), Gaps = 18/328 (5%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ D+ A+ + D+GI FDTAEVY A Sbjct: 42 LGKSGLRVSCLGLGTW----VTFGGQIT-DEM----AEHLMTLAYDNGINLFDTAEVYAA 92 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E +LG IK++ + + I TK A R +I LK SL R Sbjct: 93 G-----KAEVVLGNIIKKKGWRRS-SLVITTKIFWGGKAETERGLSRKHIIEGLKASLER 146 Query: 551 LGVSSVESYQLHWPGI-WGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRG 727 L + V+ + P E + + QG+ G S +S + +A+ ++ Sbjct: 147 LQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFN 206 Query: 728 -VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPP---TG 895 +P Q Y + R E + ++G+ + +SP+A G ++GKY PP Sbjct: 207 LIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRAS 266 Query: 896 PRGRIYTSDFL-----SKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPI-PGAKN 1057 +G + D + + Q + +++ I T Q+ + W + V + GA N Sbjct: 267 LKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASN 326 Query: 1058 AEQAREFAGALGWL--LTEQEVEELRSM 1135 AEQ E GA+ L L+ V E+ S+ Sbjct: 327 AEQLMENIGAIQVLPKLSSSIVHEIDSI 354
>Q9PTM4:KCAB3_XENLA Voltage-gated potassium channel subunit beta-3 - Xenopus laevis| (African clawed frog) Length = 401 Score = 81.6 bits (200), Expect = 7e-15 Identities = 86/333 (25%), Positives = 138/333 (41%), Gaps = 26/333 (7%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ + + A+ + + G+ FDTAEVY A Sbjct: 76 LGKSGLRVSCLGLGTW----VTFGSQISDEV-----AENLMTVAYEHGVNLFDTAEVYAA 126 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E LG+ +K++ E + + TK A R +I L+GSL R Sbjct: 127 G-----RAERTLGKILKKK-EWRRSSYVVTTKIYWGGQAETERGLSRKHIIEGLRGSLER 180 Query: 551 LGVSSVESYQLHWPGIWGN--------EGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAH 706 L + V+ ++ N E + + QG+ G S +S + +A+ Sbjct: 181 LQLDYVDI-------VFANRMDPNSPMEEIVRAMTFVINQGMAMYWGTSRWSAMEIMEAY 233 Query: 707 DRLKKRG-VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPAN 883 ++ +P Q Y L R E + ++G+ + +SP+A G +TGKYT Sbjct: 234 SVARQFNLIPPVCEQAEYHLFQREKVETQLPELYHKIGVGSMTWSPLACGLITGKYTDTV 293 Query: 884 PPTGPRGRIYTSDFL---------SKLQPLINKIRVIGGSYDKTPTQVVLNW-LICQGNV 1033 P R +L K + ++ I + T TQ+ + W L +G Sbjct: 294 PEKS-RASFKGYHWLKEKAISQEGKKQHSKVKELHPIADRLNCTVTQLAIAWCLRSEGVS 352 Query: 1034 VPIPGAKNAEQAREFAGALGWL--LTEQEVEEL 1126 + G N EQ E GA+ L LT Q V E+ Sbjct: 353 SVLLGVSNIEQLLENLGAIQVLPHLTPQLVTEI 385
>P76234:YEAE_ECOLI Uncharacterized protein yeaE - Escherichia coli| Length = 284 Score = 81.3 bits (199), Expect = 9e-15 Identities = 80/309 (25%), Positives = 133/309 (43%), Gaps = 1/309 (0%) Frame = +2 Query: 203 MLGASG-VAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVY 379 M+ SG V++ +G G W G+ D + K A A ++ G+T DTAE+Y Sbjct: 5 MIQFSGDVSLPAVGQGTWYMGE---------DASQRKTEVAALRAGIELGLTLIDTAEMY 55 Query: 380 GAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVISALKGSLSRLGV 559 G + + E+L G ++E+ V + +K PW G I+A + SL RL Sbjct: 56 ADGGAEKVVGEALTG--LREK-------VFLVSK--VYPWNAGGQKAINACEASLRRLNT 104 Query: 560 SSVESYQLHWPGIWGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLA 739 ++ Y LHW G + E + + QG ++ GVSN +++ G A Sbjct: 105 DYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQ--LPGGNQCA 162 Query: 740 SNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTS 919 +NQV Y L R E + + C + + ++AYSP+AQ GR+ Sbjct: 163 TNQVLYHLGSRGIEYD-LLPWCQQQQMPVMAYSPLAQA----------------GRLRNG 205 Query: 920 DFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWL 1099 + + + I +++ + QV+L W+I V+ IP A ++ A L Sbjct: 206 LLKNAV------VNEIAHAHNISAAQVLLAWVISHQGVMAIPKAATIAHVQQNAAVLEVE 259 Query: 1100 LTEQEVEEL 1126 L+ E+ L Sbjct: 260 LSSAELAML 268
>Q13303:KCAB2_HUMAN Voltage-gated potassium channel subunit beta-2 - Homo sapiens (Human)| Length = 367 Score = 80.5 bits (197), Expect = 2e-14 Identities = 85/328 (25%), Positives = 141/328 (42%), Gaps = 18/328 (5%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ D+ A+ + D+GI FDTAEVY A Sbjct: 42 LGKSGLRVSCLGLGTW----VTFGGQIT-DEM----AEQLMTLAYDNGINLFDTAEVYAA 92 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E +LG IK++ + + I TK A R +I LK SL R Sbjct: 93 G-----KAEVVLGNIIKKKGWRRS-SLVITTKIFWGGKAETERGLSRKHIIEGLKASLER 146 Query: 551 LGVSSVESYQLHWPGI-WGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRG 727 L + V+ + P E + + QG+ G S +S + +A+ ++ Sbjct: 147 LQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFN 206 Query: 728 V-PLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPP---TG 895 + P Q Y + R E + ++G+ + +SP+A G ++GKY PP Sbjct: 207 LTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRAS 266 Query: 896 PRGRIYTSDFL-----SKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPI-PGAKN 1057 +G + D + + Q + +++ I T Q+ + W + V + GA N Sbjct: 267 LKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASN 326 Query: 1058 AEQAREFAGALGWL--LTEQEVEELRSM 1135 A+Q E GA+ L L+ + E+ S+ Sbjct: 327 ADQLMENIGAIQVLPKLSSSIIHEIDSI 354
>P40691:A115_TOBAC Auxin-induced protein PCNT115 - Nicotiana tabacum (Common tobacco)| Length = 307 Score = 79.7 bits (195), Expect = 3e-14 Identities = 87/307 (28%), Positives = 133/307 (43%), Gaps = 17/307 (5%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG+ G+ V+ G+G + F + D +++SGIT DT++VYG Sbjct: 13 LGSQGLEVSAQGLGCMGM------SAFYGPPKPEPDMIQLIHHAINSGITLLDTSDVYGP 66 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKFA--------ALPWRFGRGS---VISAL 532 + E LLG+ +K + V +ATKF A R G V +A Sbjct: 67 HTN-----EILLGKALKGGTRER---VVLATKFGIVLGDEKKAEGKRAVHGDPAYVRAAC 118 Query: 533 KGSLSRLGVSSVESYQLHWPGIWGN-EGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHD 709 + SL RL + ++ Y H E + L E+G +K +G+S S +R AH Sbjct: 119 EASLKRLDIDCIDLYYQHRVDTRVPIEITVGELKKLVEEGKLKYIGLSEASASTIRRAH- 177 Query: 710 RLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPP 889 P+ + Q+ +SL R+ EE + C ELGI ++AYSP+ +G L+ Sbjct: 178 ----AVHPITAVQLEWSLWSRDVEEE-IIPTCRELGIGIVAYSPLGRGFLSSGPKLLEDM 232 Query: 890 TGPRGRIYTSDF----LSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGN-VVPIPGAK 1054 + R Y F L + L +I + TP+Q+ L W+ QGN V PIPG Sbjct: 233 SNEDYRKYLPRFQAENLENNKNLYERICEMAVRKGCTPSQLALAWVHHQGNDVCPIPGTT 292 Query: 1055 NAEQARE 1075 E + Sbjct: 293 KIENLNQ 299
>Q9PTM5:KCAB2_XENLA Voltage-gated potassium channel subunit beta-2 - Xenopus laevis| (African clawed frog) Length = 367 Score = 79.3 bits (194), Expect = 3e-14 Identities = 81/311 (26%), Positives = 132/311 (42%), Gaps = 16/311 (5%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ D+ A+ + D+GI FDTAEVY A Sbjct: 42 LGKSGLRVSCLGLGTW----VTFGGQIT-DEM----AEQLMTLAYDNGINLFDTAEVYAA 92 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E +LG IK++ + + I TK A R +I LK SL R Sbjct: 93 G-----KAEVVLGNIIKKKGWRRS-SLVITTKIFWGGKAETERGLSRKHIIEGLKASLER 146 Query: 551 LGVSSVESYQLHWPGI-WGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRG 727 L + V+ + P E + + QG+ G S +S + +A+ ++ Sbjct: 147 LQLDYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFN 206 Query: 728 -VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPP---TG 895 +P Q Y + R E + ++G+ + +SP+A G ++GKY PP Sbjct: 207 LIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDGGIPPYSRAS 266 Query: 896 PRGRIYTSDFL-----SKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPI-PGAKN 1057 +G + D + + Q + + + I T Q+ + W + V + GA N Sbjct: 267 LKGYQWLKDKILSEEGRRQQAKLKEFQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASN 326 Query: 1058 AEQAREFAGAL 1090 A+Q E GA+ Sbjct: 327 ADQLLENIGAI 337
>Q27955:KCAB2_BOVIN Voltage-gated potassium channel subunit beta-2 - Bos taurus (Bovine)| Length = 367 Score = 79.3 bits (194), Expect = 3e-14 Identities = 84/328 (25%), Positives = 141/328 (42%), Gaps = 18/328 (5%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ D+ A+ + D+GI FDTAEVY A Sbjct: 42 LGKSGLRVSCLGLGTW----VTFGGQIT-DEM----AEQLMTLAYDNGINLFDTAEVYAA 92 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E +LG IK++ + + I TK A R +I LK SL R Sbjct: 93 G-----KAEVVLGNIIKKKGWRRS-SLVITTKIFWGGKAETERGLSRKHIIEGLKASLER 146 Query: 551 LGVSSVESYQLHWPGI-WGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRG 727 L + V+ + P E + + QG+ G S +S + +A+ ++ Sbjct: 147 LQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFN 206 Query: 728 -VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPP---TG 895 +P Q Y + R E + ++G+ + +SP+A G ++GKY PP Sbjct: 207 LIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRAS 266 Query: 896 PRGRIYTSDFL-----SKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPI-PGAKN 1057 +G + D + + Q + +++ I T Q+ + W + V + GA + Sbjct: 267 LKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASS 326 Query: 1058 AEQAREFAGALGWL--LTEQEVEELRSM 1135 A+Q E GA+ L L+ + E+ S+ Sbjct: 327 ADQLMENIGAIQVLPKLSSSIIHEIDSI 354
>P63144:KCAB1_RAT Voltage-gated potassium channel subunit beta-1 - Rattus norvegicus| (Rat) Length = 401 Score = 77.8 bits (190), Expect = 1e-13 Identities = 91/359 (25%), Positives = 147/359 (40%), Gaps = 21/359 (5%) Frame = +2 Query: 128 RRTAGFRPPRAVT-SEGAAVEDGSKAM-LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDR 301 R F P ++ E A + G K LG SG+ V+ LG+G W T+ + Sbjct: 48 RSLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTW----VTFGGQISDEV- 102 Query: 302 KLKDAKGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATK 481 A+ + +SG+ FDTAEVY AG +E +LG IK++ + + I TK Sbjct: 103 ----AERLMTIAYESGVNLFDTAEVYAAG-----KAEVILGSIIKKKGWRRS-SLVITTK 152 Query: 482 F-----AALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWPGI-WGNEGYLDGLADAYE 643 A R +I LKGSL RL + V+ + P E + + Sbjct: 153 LYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVIN 212 Query: 644 QGLVKSVGVSNYSEKRLRDAHDRLKKRG-VPLASNQVNYSLIYRNPEENGVKAACDELGI 820 QG+ G S +S + +A+ ++ +P Q Y L R E + ++G+ Sbjct: 213 QGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGV 272 Query: 821 TLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLS---------KLQPLINKIRVIGG 973 + +SP+A G ++GKY P + R + +L K Q + + I Sbjct: 273 GAMTWSPLACGIISGKYGNGVPESS-RASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAE 331 Query: 974 SYDKTPTQVVLNWLICQGNVVPI-PGAKNAEQAREFAGALGWL--LTEQEVEELRSMAR 1141 T Q+ + W + V + G+ EQ E GA+ L +T V E+ ++ R Sbjct: 332 RLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILR 390
>P63143:KCAB1_MOUSE Voltage-gated potassium channel subunit beta-1 - Mus musculus (Mouse)| Length = 401 Score = 77.8 bits (190), Expect = 1e-13 Identities = 91/359 (25%), Positives = 147/359 (40%), Gaps = 21/359 (5%) Frame = +2 Query: 128 RRTAGFRPPRAVT-SEGAAVEDGSKAM-LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDR 301 R F P ++ E A + G K LG SG+ V+ LG+G W T+ + Sbjct: 48 RSLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTW----VTFGGQISDEV- 102 Query: 302 KLKDAKGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATK 481 A+ + +SG+ FDTAEVY AG +E +LG IK++ + + I TK Sbjct: 103 ----AERLMTIAYESGVNLFDTAEVYAAG-----KAEVILGSIIKKKGWRRS-SLVITTK 152 Query: 482 F-----AALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWPGI-WGNEGYLDGLADAYE 643 A R +I LKGSL RL + V+ + P E + + Sbjct: 153 LYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVIN 212 Query: 644 QGLVKSVGVSNYSEKRLRDAHDRLKKRG-VPLASNQVNYSLIYRNPEENGVKAACDELGI 820 QG+ G S +S + +A+ ++ +P Q Y L R E + ++G+ Sbjct: 213 QGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGV 272 Query: 821 TLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLS---------KLQPLINKIRVIGG 973 + +SP+A G ++GKY P + R + +L K Q + + I Sbjct: 273 GAMTWSPLACGIISGKYGNGVPESS-RASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAE 331 Query: 974 SYDKTPTQVVLNWLICQGNVVPI-PGAKNAEQAREFAGALGWL--LTEQEVEELRSMAR 1141 T Q+ + W + V + G+ EQ E GA+ L +T V E+ ++ R Sbjct: 332 RLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILR 390
>Q4PJK1:KCAB1_BOVIN Voltage-gated potassium channel subunit beta-1 - Bos taurus (Bovine)| Length = 401 Score = 77.8 bits (190), Expect = 1e-13 Identities = 91/359 (25%), Positives = 147/359 (40%), Gaps = 21/359 (5%) Frame = +2 Query: 128 RRTAGFRPPRAVT-SEGAAVEDGSKAM-LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDR 301 R F P ++ E A + G K LG SG+ V+ LG+G W T+ + Sbjct: 48 RSLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTW----VTFGGQISDEV- 102 Query: 302 KLKDAKGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATK 481 A+ + +SG+ FDTAEVY AG +E +LG IK++ + + I TK Sbjct: 103 ----AERLMTIAYESGVNLFDTAEVYAAG-----KAEVILGSIIKKKGWRRS-SLVITTK 152 Query: 482 F-----AALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWPGI-WGNEGYLDGLADAYE 643 A R +I LKGSL RL + V+ + P E + + Sbjct: 153 LYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVIN 212 Query: 644 QGLVKSVGVSNYSEKRLRDAHDRLKKRG-VPLASNQVNYSLIYRNPEENGVKAACDELGI 820 QG+ G S +S + +A+ ++ +P Q Y L R E + ++G+ Sbjct: 213 QGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGV 272 Query: 821 TLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLS---------KLQPLINKIRVIGG 973 + +SP+A G ++GKY P + R + +L K Q + + I Sbjct: 273 GAMTWSPLACGIISGKYGNGVPESS-RASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAE 331 Query: 974 SYDKTPTQVVLNWLICQGNVVPI-PGAKNAEQAREFAGALGWL--LTEQEVEELRSMAR 1141 T Q+ + W + V + G+ EQ E GA+ L +T V E+ ++ R Sbjct: 332 RLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILR 390
>P49249:IN22_MAIZE IN2-2 protein - Zea mays (Maize)| Length = 306 Score = 76.6 bits (187), Expect = 2e-13 Identities = 71/236 (30%), Positives = 116/236 (49%), Gaps = 10/236 (4%) Frame = +2 Query: 176 AAVEDGSKAMLGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGIT 355 AA+ + LG+ G+ V+ G+G G + ++ + + +K +VD+G+T Sbjct: 3 AALVSVPRIKLGSQGLEVSAQGLGCM--GMSAFYGPPKPESEMIK----LIHHAVDAGVT 56 Query: 356 FFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGS------ 517 F DT++VYG +E LLG+ + + +EKV+ +ATKF F G Sbjct: 57 FLDTSDVYGPH-----TNEVLLGKAL-QGGVREKVE--LATKFGV---SFADGKREIHGD 105 Query: 518 ---VISALKGSLSRLGVSSVESYQLH-WPGIWGNEGYLDGLADAYEQGLVKSVGVSNYSE 685 V +A +GS RLGV ++ Y H E + L E+G +K +G+S S Sbjct: 106 PAYVRTACEGSFKRLGVDCIDLYYQHRIDKRVPIEVTIGELKKLVEEGKIKYIGLSEASA 165 Query: 686 KRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQG 853 +R AH P+ + Q+ +SL R+ EE+ + C ELGI ++AYSP+ +G Sbjct: 166 STIRRAH-----AVHPITAVQLEWSLWSRDAEED-IIPTCRELGIGIVAYSPLGRG 215
>O14295:PLR1_SCHPO Pyridoxal reductase - Schizosaccharomyces pombe (Fission yeast)| Length = 333 Score = 76.3 bits (186), Expect = 3e-13 Identities = 80/333 (24%), Positives = 144/333 (43%), Gaps = 17/333 (5%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVS 394 SG V +G G W Q D ++A + ++ G ++D E YG V Sbjct: 5 SGFKVGPIGFGLMG----LTWKPKQTPD---EEAFEVMNYALSQGSNYWDAGEFYG--VD 55 Query: 395 GAINSESLLGRFIK---ERQEKEKVDVAIATKFAALPWRFGRGSVISALKGSLSRL-GVS 562 ++ LL R+ + E K + V F L V +++ ++ L G Sbjct: 56 PPTSNLDLLARYFEKYPENANKVFLSVKGGLDFKTLVPDGNPDFVSKSVENVIAHLRGTK 115 Query: 563 SVESYQLHW--PGIWGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPL 736 ++ +Q P + E + L + G + VG+S S + ++ AH VP+ Sbjct: 116 KLDLFQCARVDPNV-PIETTMKTLKGFVDSGKISCVGLSEVSAETIKRAH-----AVVPI 169 Query: 737 ASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGK---------YTPANPP 889 A+ +V YSL R+ E NG+ C +L I +IAYSP +G LTG+ + + P Sbjct: 170 AAVEVEYSLFSRDIETNGIMDICRKLSIPIIAYSPFCRGLLTGRIKTVEDLKEFAKSFPF 229 Query: 890 TGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGN--VVPIPGAKNAE 1063 R ++ D +K P + + + + T + L +++ GN V+PIPG+ + Sbjct: 230 LEYLDR-FSPDVFAKNLPFLQAVEQLAKKFGMTMPEFSLLFIMASGNGLVIPIPGSTSVS 288 Query: 1064 QAREFAGALGWLLTEQEVEELRSMAREVKPVMG 1162 + + AL L+ ++ +E + + + P+ G Sbjct: 289 RTKSNLNALNKSLSPEQFKEAKEVLSKY-PIYG 320
>Q9XT31:KCAB1_RABIT Voltage-gated potassium channel subunit beta-1 - Oryctolagus| cuniculus (Rabbit) Length = 419 Score = 75.9 bits (185), Expect = 4e-13 Identities = 84/331 (25%), Positives = 137/331 (41%), Gaps = 19/331 (5%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ + A+ + +SG+ FDTAEVY A Sbjct: 94 LGKSGLRVSCLGLGTW----VTFGGQISDEV-----AERLMTIAYESGVNLFDTAEVYAA 144 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E +LG IK++ + + I TK A R +I LKGSL R Sbjct: 145 G-----KAEVILGSIIKKKGWRRS-SLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR 198 Query: 551 LGVSSVESYQLHWPGI-WGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRG 727 L + V+ + P E + + QG+ G S +S + +A+ ++ Sbjct: 199 LQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN 258 Query: 728 -VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRG 904 +P Q Y L R E + ++G+ + +SP+A G ++GKY P + R Sbjct: 259 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESS-RA 317 Query: 905 RIYTSDFLS---------KLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPI-PGAK 1054 + +L K Q + + I T Q+ + W + V + G+ Sbjct: 318 SLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSS 377 Query: 1055 NAEQAREFAGALGWL--LTEQEVEELRSMAR 1141 EQ E GA+ L +T V E+ ++ R Sbjct: 378 TPEQLIENLGAIQVLPKMTSHVVNEIDNILR 408
>Q28528:KCAB1_MUSPU Voltage-gated potassium channel subunit beta-1 - Mustela putorius| (European polecat) Length = 408 Score = 75.9 bits (185), Expect = 4e-13 Identities = 84/331 (25%), Positives = 137/331 (41%), Gaps = 19/331 (5%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ + A+ + +SG+ FDTAEVY A Sbjct: 83 LGKSGLRVSCLGLGTW----VTFGGQISDEV-----AERLMTIAYESGVNLFDTAEVYAA 133 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E +LG IK++ + + I TK A R +I LKGSL R Sbjct: 134 G-----KAEVILGSIIKKKGWRRS-SLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR 187 Query: 551 LGVSSVESYQLHWPGI-WGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRG 727 L + V+ + P E + + QG+ G S +S + +A+ ++ Sbjct: 188 LQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN 247 Query: 728 -VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRG 904 +P Q Y L R E + ++G+ + +SP+A G ++GKY P + R Sbjct: 248 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESS-RA 306 Query: 905 RIYTSDFLS---------KLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPI-PGAK 1054 + +L K Q + + I T Q+ + W + V + G+ Sbjct: 307 SLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSS 366 Query: 1055 NAEQAREFAGALGWL--LTEQEVEELRSMAR 1141 EQ E GA+ L +T V E+ ++ R Sbjct: 367 TPEQLIENLGAIQVLPKMTSHVVNEIDNILR 397
>Q14722:KCAB1_HUMAN Voltage-gated potassium channel subunit beta-1 - Homo sapiens (Human)| Length = 419 Score = 75.9 bits (185), Expect = 4e-13 Identities = 84/331 (25%), Positives = 137/331 (41%), Gaps = 19/331 (5%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ + A+ + +SG+ FDTAEVY A Sbjct: 94 LGKSGLRVSCLGLGTW----VTFGGQISDEV-----AERLMTIAYESGVNLFDTAEVYAA 144 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E +LG IK++ + + I TK A R +I LKGSL R Sbjct: 145 G-----KAEVILGSIIKKKGWRRS-SLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR 198 Query: 551 LGVSSVESYQLHWPGI-WGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRG 727 L + V+ + P E + + QG+ G S +S + +A+ ++ Sbjct: 199 LQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN 258 Query: 728 -VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRG 904 +P Q Y L R E + ++G+ + +SP+A G ++GKY P + R Sbjct: 259 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESS-RA 317 Query: 905 RIYTSDFLS---------KLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPI-PGAK 1054 + +L K Q + + I T Q+ + W + V + G+ Sbjct: 318 SLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSS 377 Query: 1055 NAEQAREFAGALGWL--LTEQEVEELRSMAR 1141 EQ E GA+ L +T V E+ ++ R Sbjct: 378 TPEQLIENLGAIQVLPKMTSHVVNEIDNILR 408
>Q7G764:NADO1_ORYSJ Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp.| japonica (Rice) Length = 321 Score = 75.5 bits (184), Expect = 5e-13 Identities = 76/296 (25%), Positives = 124/296 (41%), Gaps = 20/296 (6%) Frame = +2 Query: 308 KDAKGAFDASVDSGITFFDTAEVYGA-GVSGAINSESLLGRFIKERQEKEKVDVAIATKF 484 +D A +++ G FDTA +Y G G +E++ I R DV + +K Sbjct: 32 EDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASR-----ADVFVTSKI 86 Query: 485 AALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWPGIW--GN----------------E 610 GR V+ A + +L LG+ V+ +HWP GN E Sbjct: 87 WCSDLHAGR--VVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDME 144 Query: 611 GYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENG 790 G G+ + + GL +++GVSN+S K+L L V A NQV + ++ ++ Sbjct: 145 GVWRGMEECHRLGLARAIGVSNFSAKKLEQL---LSLAAVRPAVNQVEVNPMW---QQRT 198 Query: 791 VKAACDELGITLIAYSPI-AQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVI 967 ++ C G+ L YSP+ A+G P G D ++ I Sbjct: 199 LREVCRREGVQLCGYSPLGAKGT-------------PWGSAAVMD--------SGVLQEI 237 Query: 968 GGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 G+ KT Q+ L WL QG+V+ + N ++ +E W LT++E E + + Sbjct: 238 AGAKGKTLAQICLRWLYEQGDVLLVK-TYNEKRMKENLDIFNWELTDEERERISQL 292
>P0A9T5:TAS_SHIFL Protein tas - Shigella flexneri| Length = 346 Score = 75.1 bits (183), Expect = 6e-13 Identities = 71/268 (26%), Positives = 111/268 (41%), Gaps = 34/268 (12%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVS 394 S + V+ LG+G ++G+ DA D +V GI D AE+Y Sbjct: 9 SSLEVSTLGLGTMTFGE----------QNSEADAHAQLDYAVAQGINLIDVAEMYPVPPR 58 Query: 395 GAIN--SESLLGRFIKERQEKEKVDVAIAT--------KFAALPWRFGRGSVISALKGSL 544 +E+ +G ++ + +EK+ +A K R ++ AL SL Sbjct: 59 PETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSL 118 Query: 545 SRLGVSSVESYQLHWP----GIWGNEGY--------------LDGLADAYEQGLVKSVGV 670 RL ++ YQ+HWP +G GY LD LA+ G ++ +GV Sbjct: 119 KRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGV 178 Query: 671 SNYSE------KRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIA 832 SN + L D HD + + + Q YSL+ R+ E G+ G+ L+A Sbjct: 179 SNETAFGVMRYLHLADKHDLPR-----IVTIQNPYSLLNRSFEV-GLAEVSQYEGVELLA 232 Query: 833 YSPIAQGALTGKYTPANPPTGPRGRIYT 916 YS + G LTGKY P G R +++ Sbjct: 233 YSCLGFGTLTGKYLNGAKPAGARNTLFS 260
>P0A9T4:TAS_ECOLI Protein tas - Escherichia coli| Length = 346 Score = 75.1 bits (183), Expect = 6e-13 Identities = 71/268 (26%), Positives = 111/268 (41%), Gaps = 34/268 (12%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVS 394 S + V+ LG+G ++G+ DA D +V GI D AE+Y Sbjct: 9 SSLEVSTLGLGTMTFGE----------QNSEADAHAQLDYAVAQGINLIDVAEMYPVPPR 58 Query: 395 GAIN--SESLLGRFIKERQEKEKVDVAIAT--------KFAALPWRFGRGSVISALKGSL 544 +E+ +G ++ + +EK+ +A K R ++ AL SL Sbjct: 59 PETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSL 118 Query: 545 SRLGVSSVESYQLHWP----GIWGNEGY--------------LDGLADAYEQGLVKSVGV 670 RL ++ YQ+HWP +G GY LD LA+ G ++ +GV Sbjct: 119 KRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGV 178 Query: 671 SNYSE------KRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIA 832 SN + L D HD + + + Q YSL+ R+ E G+ G+ L+A Sbjct: 179 SNETAFGVMRYLHLADKHDLPR-----IVTIQNPYSLLNRSFEV-GLAEVSQYEGVELLA 232 Query: 833 YSPIAQGALTGKYTPANPPTGPRGRIYT 916 YS + G LTGKY P G R +++ Sbjct: 233 YSCLGFGTLTGKYLNGAKPAGARNTLFS 260
>P26690:6DCS_SOYBN NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean)| Length = 315 Score = 75.1 bits (183), Expect = 6e-13 Identities = 77/306 (25%), Positives = 128/306 (41%), Gaps = 28/306 (9%) Frame = +2 Query: 308 KDAKGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIAT 478 KD K A +V G FDTA YG SE LG +KE V D+ + + Sbjct: 36 KDTKEAIIEAVKQGYRHFDTAAAYG--------SEQALGEALKEAIHLGLVSRQDLFVTS 87 Query: 479 KFAALPWRFGRGS--VISALKGSLSRLGVSSVESYQLHWP-------------------- 592 K W V+ AL+ SL L + ++ Y +HWP Sbjct: 88 KL----WVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPF 143 Query: 593 ---GIWGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSL 763 G+W + + + + GL K++GVSN+S K+L++ L + +QV +L Sbjct: 144 DVKGVW------ESMEECQKLGLTKAIGVSNFSVKKLQNL---LSVATIRPVVDQVEMNL 194 Query: 764 IYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQP 943 + ++ ++ C E GI + A+SP+ +GA G + +D L + Sbjct: 195 AW---QQKKLREFCKENGIIVTAFSPLRKGASRGP-----------NEVMENDVLKE--- 237 Query: 944 LINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEE 1123 I ++ K+ QV L WL QG V +P + + E+ + W LTEQ+ + Sbjct: 238 -------IAEAHGKSIAQVSLRWLYEQG-VTFVPKSYDKERMNQNLHIFDWALTEQDHHK 289 Query: 1124 LRSMAR 1141 + +++ Sbjct: 290 ISQISQ 295
>Q9PWR1:KCAB1_CHICK Voltage-gated potassium channel subunit beta-1 - Gallus gallus| (Chicken) Length = 401 Score = 74.7 bits (182), Expect = 8e-13 Identities = 88/354 (24%), Positives = 144/354 (40%), Gaps = 21/354 (5%) Frame = +2 Query: 128 RRTAGFRPPRAVT-SEGAAVEDGSKAM-LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDR 301 R F P ++ E A + G K LG SG+ V+ LG+G W T+ + Sbjct: 48 RSLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTW----VTFGGQISDEV- 102 Query: 302 KLKDAKGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATK 481 A+ + +SG+ FDTAEVY AG +E +LG +K++ + + I TK Sbjct: 103 ----AEQLMTIAYESGVNLFDTAEVYAAG-----KAEVILGNILKKKGWRRS-SLVITTK 152 Query: 482 F-----AALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWP-GIWGNEGYLDGLADAYE 643 A R +I L+ SL RL + V+ + P E + + Sbjct: 153 LYWGGKAETERGLSRKHIIEGLRASLQRLQLEYVDVVFANRPDNNTPMEEIVRAMTHVIN 212 Query: 644 QGLVKSVGVSNYSEKRLRDAHDRLKKRG-VPLASNQVNYSLIYRNPEENGVKAACDELGI 820 QG+ G S +S + +A+ ++ +P Q Y L R E + ++G+ Sbjct: 213 QGMAMYWGTSRWSAMEIMEAYSVARQFNLIPPVCEQAEYHLFQREKVEVQLPELYHKIGV 272 Query: 821 TLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLS---------KLQPLINKIRVIGG 973 + +SP+A G ++GKY P + R + +L K Q + + I Sbjct: 273 GAMTWSPLACGIISGKYGNGVPESS-RAALKCYQWLKEKIISEEGRKQQTKLKDLSPIAE 331 Query: 974 SYDKTPTQVVLNWLICQGNVVPI-PGAKNAEQAREFAGALGWL--LTEQEVEEL 1126 T Q+ + W + V + G+ N EQ E GA+ L +T V E+ Sbjct: 332 RLGCTLPQLAVAWCLRNEGVSSVLLGSSNPEQLIENLGAIQVLPKMTSHIVNEI 385
>P22045:P100_LEIMA Probable reductase - Leishmania major| Length = 284 Score = 74.3 bits (181), Expect = 1e-12 Identities = 85/326 (26%), Positives = 137/326 (42%), Gaps = 13/326 (3%) Frame = +2 Query: 197 KAMLGAS-GVAVTKLGIGAWSW--GDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDT 367 KAM+ S GV + + G+G W G+ T + A + ++ +G DT Sbjct: 6 KAMVTLSNGVKMPQFGLGVWQSPAGEVT---------------ENAVNWALCAGYRHIDT 50 Query: 368 AEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRG--SVISALKGS 541 A +Y N ES+ +E DV I TK W +G S ++A + S Sbjct: 51 AAIYK-------NEESVGAGLRASGVPRE--DVFITTKL----WNTEQGYESTLAAFEES 97 Query: 542 LSRLGVSSVESYQLHWP---GIWGNEG--YLD---GLADAYEQGLVKSVGVSNYSEKRLR 697 +LGV ++ Y +HWP I EG YLD Y++ V+++GVSN+ L Sbjct: 98 RQKLGVDYIDLYLIHWPRGKDILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLE 157 Query: 698 DAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTP 877 D + + VN ++ + ++A CD I + A+SP+ QG L Sbjct: 158 DV------LAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQGKLL----- 206 Query: 878 ANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKN 1057 +NP + IG Y+KT QV+L W I Q N++ IP + + Sbjct: 207 SNP----------------------ILSAIGAKYNKTAAQVILRWNI-QKNLITIPKSVH 243 Query: 1058 AEQAREFAGALGWLLTEQEVEELRSM 1135 E+ E A + L ++V + ++ Sbjct: 244 RERIEENADIFDFELGAEDVMSIDAL 269
>O43448:KCAB3_HUMAN Voltage-gated potassium channel subunit beta-3 - Homo sapiens (Human)| Length = 404 Score = 72.4 bits (176), Expect = 4e-12 Identities = 86/332 (25%), Positives = 135/332 (40%), Gaps = 25/332 (7%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ + Q D +D + + G+ FDTAEVY A Sbjct: 83 LGKSGLRVSCLGLGTW----VTFGS--QISDETAEDV---LTVAYEHGVNLFDTAEVYAA 133 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E LG +K + + V I TK A R +I L+GSL R Sbjct: 134 G-----KAERTLGNILKSKGWRRSSYV-ITTKIFWGGQAETERGLSRKHIIEGLRGSLER 187 Query: 551 LGVSSVESYQLHWPGIWGN--------EGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAH 706 L + V+ ++ N E + + QGL G S + + +A+ Sbjct: 188 LQLGYVDI-------VFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAY 240 Query: 707 DRLKKRG-VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPAN 883 ++ +P Q + L R E + ++G+ + + P+A G +T KY Sbjct: 241 SMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRV 300 Query: 884 PPT---GPRGRIYTSDFL-----SKLQPLINKIRVIGGSYDKTPTQVVLNW-LICQGNVV 1036 P T +G + D + K Q + + + T Q+ + W L +G Sbjct: 301 PDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSS 360 Query: 1037 PIPGAKNAEQAREFAGALGWL--LTEQEVEEL 1126 + G +AEQ E GAL L LT Q V E+ Sbjct: 361 VLLGVSSAEQLIEHLGALQVLSQLTPQTVMEI 392
>P23901:ALDR_HORVU Aldose reductase - Hordeum vulgare (Barley)| Length = 320 Score = 71.2 bits (173), Expect = 9e-12 Identities = 77/334 (23%), Positives = 134/334 (40%), Gaps = 18/334 (5%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVS 394 SG A+ +G+G W G T A A ++G DTA YG Sbjct: 20 SGHAMPAVGLGTWRAGSDT--------------AHSVRTAITEAGYRHVDTAAEYGV--- 62 Query: 395 GAINSESLLGRFIKERQEK--EKVDVAIATKFAALPWRFGRGSVISALKGSLSRLGVSSV 568 E +G+ +K E ++ D+ + +K V AL+ +L L + + Sbjct: 63 -----EKEVGKGLKAAMEAGIDRKDLFVTSKIWCT--NLAPERVRPALENTLKDLQLDYI 115 Query: 569 ESYQLHWPGI----------------WGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRD 700 + Y +HWP + EG + + + GLVK +GV NY+ +L Sbjct: 116 DLYHIHWPFRLKDGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKL-- 173 Query: 701 AHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPA 880 + L+ +P A Q+ ++N + + AC + GI + AYSP+ + P Sbjct: 174 -NRLLRSAKIPPAVCQMEMHPGWKNDK---IFEACKKHGIHVTAYSPLGSSEKNLAHDPV 229 Query: 881 NPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNA 1060 ++ + NK+ +KTP QV++ W + +G V IP + Sbjct: 230 ------------------VEKVANKL-------NKTPGQVLIKWALQRGTSV-IPKSSKD 263 Query: 1061 EQAREFAGALGWLLTEQEVEELRSMAREVKPVMG 1162 E+ +E GW + E++ + L S+ E + + G Sbjct: 264 ERIKENIQVFGWEIPEEDFKVLCSIKDEKRVLTG 297
>P40690:ALKE_BABBO Aldo-keto reductase - Babesia bovis| Length = 285 Score = 70.9 bits (172), Expect = 1e-11 Identities = 57/181 (31%), Positives = 82/181 (45%), Gaps = 38/181 (20%) Frame = +2 Query: 464 VAIATKFAA----LPW------RFGRGSVISALKGSLSRLGVSSVESYQLHWPGIW---- 601 V IATK A+ L W + + +++ A+ GSLSRL ++ QLHWP + Sbjct: 3 VVIATKVASRSSHLSWLRSGDCKLSKDNILKAVDGSLSRLNTDYIDLLQLHWPDRYVPMN 62 Query: 602 --GN-------------------EGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLK 718 G+ E LD L QG ++ G+SN + + K Sbjct: 63 ANGDFHEVFHDTENMIDENSVPLEDQLDALQTLLTQGKIRHWGLSNETPWGTLRFYKLAK 122 Query: 719 KRGVPL-ASNQVNYSLIYRNPEENGVKAAC--DELGITLIAYSPIAQGALTGKYTPANPP 889 + GV AS Q++Y+L+ RN E G C GI ++AY+P+A G LTGKY P Sbjct: 123 QAGVAAPASVQLHYNLLCRNEVEKGFVELCRPQNTGIAILAYAPLAGGILTGKYLEYMDP 182 Query: 890 T 892 T Sbjct: 183 T 183
>Q7G765:NADO2_ORYSJ Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp.| japonica (Rice) Length = 322 Score = 68.2 bits (165), Expect = 8e-11 Identities = 67/298 (22%), Positives = 123/298 (41%), Gaps = 19/298 (6%) Frame = +2 Query: 308 KDAKGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFA 487 ++ A +++ G FDTA +Y G ++ + ++ + DV + +K Sbjct: 34 EETTAALLRAIELGYRHFDTARLYAT--EGCVSEA--VAEAVRRGLVASRADVFVTSKLW 89 Query: 488 ALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWPGI------------------WGNEG 613 GR V+ A + +L LG+ V+ +HWP + EG Sbjct: 90 CSDLHAGR--VVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEG 147 Query: 614 YLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGV 793 G+ + + GL +++GVSN+S K+L L V A+NQV + ++ ++ + Sbjct: 148 VWRGMEECHRLGLARAIGVSNFSAKKLEQL---LSFAVVRPAANQVEMNPMW---QQRTL 201 Query: 794 KAACDELGITLIAYSPI-AQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIG 970 + C G+ L YSP+ A+G P G D + I Sbjct: 202 REVCRREGVQLCGYSPLGAKGT-------------PWGSAAVMD--------SGVLHDIA 240 Query: 971 GSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMARE 1144 + KT Q+ L W+ QG+V+ + N + +E W LTE+E +++ + ++ Sbjct: 241 QTKGKTLAQICLRWMYEQGDVLLVK-TYNENRMKENLDIFDWELTEEERDKISKLPQQ 297
>Q63494:KCAB3_RAT Voltage-gated potassium channel subunit beta-3 - Rattus norvegicus| (Rat) Length = 404 Score = 68.2 bits (165), Expect = 8e-11 Identities = 83/336 (24%), Positives = 135/336 (40%), Gaps = 26/336 (7%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGA 385 LG SG+ V+ LG+G W T+ + Q D +D + + G+ FDTAEVY A Sbjct: 83 LGKSGLRVSCLGLGTW----VTFGS--QISDETAEDL---LTVAYEHGVNLFDTAEVYAA 133 Query: 386 GVSGAINSESLLGRFIKERQEKEKVDVAIATKF-----AALPWRFGRGSVISALKGSLSR 550 G +E LG +K + + + I TK A R +I L+GSL R Sbjct: 134 G-----KAERTLGNILKSKGWR-RSSYVITTKIFWGGQAETERGLSRKHIIEGLQGSLDR 187 Query: 551 LGVSSVESYQLHWPGIWGN--------EGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAH 706 L + V+ ++ N E + + QGL G S +S + +A+ Sbjct: 188 LQLEYVDI-------VFANRSDPSSPMEEIVRAMTYVINQGLALYWGTSRWSAAEIMEAY 240 Query: 707 DRLKKRG-VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPAN 883 ++ +P Q R E + ++G+ + +SP+A +T KY Sbjct: 241 SMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACSLITSKYDGQV 300 Query: 884 PPTGP---------RGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNW-LICQGNV 1033 P + ++ + D K Q + + I T Q+ + W L +G Sbjct: 301 PDACKATVKGYQWLKEKVQSEDG-KKQQARVTDLLPIAHQLGCTVAQLAIAWCLRSEGVS 359 Query: 1034 VPIPGAKNAEQAREFAGALGWL--LTEQEVEELRSM 1135 + G +AEQ E G+L L LT Q V E+ ++ Sbjct: 360 SVLLGVSSAEQLMEHLGSLQVLGQLTPQTVMEIDAL 395
>O60218:AK1BA_HUMAN Aldo-keto reductase family 1 member B10 - Homo sapiens (Human)| Length = 316 Score = 66.6 bits (161), Expect = 2e-10 Identities = 78/302 (25%), Positives = 130/302 (43%), Gaps = 23/302 (7%) Frame = +2 Query: 305 LKDAKGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKER-QEK--EKVDVAIA 475 L K A ++D+G D A VY +E +G I+E+ QEK ++ D+ I Sbjct: 25 LGKVKEAVKVAIDAGYRHIDCAYVY--------QNEHEVGEAIQEKIQEKAVKREDLFIV 76 Query: 476 TKFAALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWP-----------------GIWG 604 +K P F R V A + +L L +S ++ Y +HWP I G Sbjct: 77 SKL--WPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGG 134 Query: 605 NEGYLDG---LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRN 775 +LD + + ++GLVK++GVSN+S ++ ++ + P+ +NQV + Sbjct: 135 KATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV-TNQVE---CHPY 190 Query: 776 PEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINK 955 + + C GIT+ AYSP+ +P P P D K Sbjct: 191 LTQEKLIQYCHSKGITVTAYSPLG--------SPDRPWAKPEDPSLLED---------PK 233 Query: 956 IRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 I+ I + KT QV++ + I Q NV+ IP + + E + L+++E+ + S Sbjct: 234 IKEIAAKHKKTAAQVLIRFHI-QRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSF 292 Query: 1136 AR 1141 R Sbjct: 293 NR 294
>P21300:ALD1_MOUSE Aldose reductase-related protein 1 - Mus musculus (Mouse)| Length = 316 Score = 65.5 bits (158), Expect = 5e-10 Identities = 75/298 (25%), Positives = 135/298 (45%), Gaps = 23/298 (7%) Frame = +2 Query: 317 KGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFA 487 K A A++D+G D A VY ++E+ +G I+E+ ++ V D+ I +K Sbjct: 29 KEAVKAAIDAGYRHIDCAYVY--------HNENEVGEAIQEKIKENAVKREDLFIVSKLW 80 Query: 488 ALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWPGIW---------GNEG--------Y 616 A F + V A + +LS L + ++ Y +HWP + N+G + Sbjct: 81 AT--FFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNALLPKDNKGKVLLSKSTF 138 Query: 617 LDG---LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEEN 787 LD + + +QGLVK++G+SN++ ++ ++ + P+ +NQ+ S Y E+ Sbjct: 139 LDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPV-TNQIE-SHPYLTQEK- 195 Query: 788 GVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVI 967 + C GI + AYSP+ +P P P + I KI+ I Sbjct: 196 -LIQYCQSKGIAVTAYSPLG--------SPDRPYAKPEDPVVME---------IPKIKEI 237 Query: 968 GGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAR 1141 + KT QV++ + + Q NVV IP + + +E + L+E+++ + S R Sbjct: 238 AAKHKKTVAQVLIRFHV-QRNVVVIPKSVTPSRIQENLQVFDFQLSEEDMAAILSFNR 294
>Q07551:KAR_YEAST NADPH-dependent alpha-keto amide reductase - Saccharomyces cerevisiae| (Baker's yeast) Length = 312 Score = 63.9 bits (154), Expect = 1e-09 Identities = 65/277 (23%), Positives = 118/277 (42%), Gaps = 7/277 (2%) Frame = +2 Query: 347 GITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVIS 526 GI D AE+Y + +G+ + EK + + + K++ P S Sbjct: 54 GIIHIDAAEIY--------RTYPEVGKALS-LTEKPRNAIFLTDKYS--PQIKMSDSPAD 102 Query: 527 ALKGSLSRLGVSSVESYQLHWP-------GIWGNEGYLDGLADAYEQGLVKSVGVSNYSE 685 L +L ++G V+ Y LH P G+ E + D + Y+ G K++GVSN++ Sbjct: 103 GLDLALKKMGTDYVDLYLLHSPFVSKEVNGLSLEEAWKD-MEQLYKSGKAKNIGVSNFA- 160 Query: 686 KRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTG 865 + D LK V NQ+ +S +N + G+ C E I + AYSP+ Sbjct: 161 --VEDLQRILKVAEVKPQVNQIEFSPFLQN-QTPGIYKFCQEHDILVEAYSPL------- 210 Query: 866 KYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIP 1045 GP + D QP ++ + Y K+ Q++L W+ +G V+P+ Sbjct: 211 ---------GPLQKKTAQD---DSQPFFEYVKELSEKYIKSEAQIILRWVTKRG-VLPVT 257 Query: 1046 GAKNAEQAREFAGALGWLLTEQEVEELRSMAREVKPV 1156 + ++ + + LT +EV+++ + E +P+ Sbjct: 258 TSSKPQRISDAQNLFSFDLTAEEVDKITELGLEHEPL 294
>Q02895:YP088_YEAST Putative aryl-alcohol dehydrogenase YPL088W - Saccharomyces| cerevisiae (Baker's yeast) Length = 342 Score = 63.5 bits (153), Expect = 2e-09 Identities = 87/334 (26%), Positives = 140/334 (41%), Gaps = 27/334 (8%) Frame = +2 Query: 206 LGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRK--LKDAKGAFDASVDSGITFFDTAEVY 379 LG SG+ ++ + IG S+G W D+ +D+ K K +D G+ FDTA+ Y Sbjct: 9 LGNSGLKISPIVIGCMSYGSKK-WADWVIEDKTQIFKIMKHCYD----KGLRTFDTADFY 63 Query: 380 GAGVSGAINSESLLGRFIKER----------QEKEKVDV---AIATKFAALPWRFGRG-- 514 G+S I E L IK E +D+ +F L RG Sbjct: 64 SNGLSERIIKEFLEYYSIKRETVVIMTKIYFPVDETLDLHHNFTLNEFEELDLSNQRGLS 123 Query: 515 --SVISALKGSLSRLGVSSVESYQLH-WPGIWGNEGYLDGLADAYEQGLVKSVGVSNYSE 685 +I+ ++ S+ RLG + ++ Q+H + + L D E G V+ +G S+ Sbjct: 124 RKHIIAGVENSVKRLG-TYIDLLQIHRLDHETPMKEIMKALNDVVEAGHVRYIGASSMLA 182 Query: 686 KRLRDAHDRLKKRG-VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALT 862 + K G S+Q Y+L+YR E + A I L+ +SP A+G LT Sbjct: 183 TEFAELQFTADKYGWFQFISSQSYYNLLYREDERELIPFA-KRHNIGLLPWSPNARGMLT 241 Query: 863 GKYTPANPPT-----GPRGRIYTSDFLSKLQ-PLINKIRVIGGSYDKTPTQVVLNWLICQ 1024 P N T P + D L + Q +IN++ + + + + W++ + Sbjct: 242 ---RPLNQSTDRIKSDPTFKSLHLDNLEEEQKEIINRVEKVSKDKKVSMAMLSIAWVLHK 298 Query: 1025 GNVVPIPGAKNAEQAREFAGALGWLLTEQEVEEL 1126 G PI G + E AL LTE+E++ L Sbjct: 299 G-CHPIVGLNTTARVDEAIAALQVTLTEEEIKYL 331
>P45377:ALD2_MOUSE Aldose reductase-related protein 2 - Mus musculus (Mouse)| Length = 316 Score = 62.0 bits (149), Expect = 6e-09 Identities = 71/298 (23%), Positives = 134/298 (44%), Gaps = 23/298 (7%) Frame = +2 Query: 317 KGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFA 487 K A A++D+G D A Y +E+ +G I+E+ +++ V D+ I +K Sbjct: 29 KEAVKAAIDAGYRHIDCAYAYC--------NENEVGEAIQEKIKEKAVQREDLFIVSKL- 79 Query: 488 ALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWP-GIW--------GNEGYL------- 619 P F + + A + +L+ L + ++ Y +HWP G+ ++G + Sbjct: 80 -WPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGRILTSKTTF 138 Query: 620 ----DGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEEN 787 +G+ + +QGLVK++GVSN++ ++ ++ + P+ +NQV + + Sbjct: 139 LEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPV-TNQVE---CHPYLTQE 194 Query: 788 GVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVI 967 + C GI++ AYSP+ +P P P D KI+ I Sbjct: 195 KLIQYCHSKGISVTAYSPLG--------SPDRPSAKPEDPSLLED---------PKIKEI 237 Query: 968 GGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAR 1141 ++KT QV++ + I Q NVV IP + + +E + L+++E+ + S R Sbjct: 238 AAKHEKTSAQVLIRFHI-QRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNR 294
>Q06494:PLR1_YEAST Putative pyridoxal reductase - Saccharomyces cerevisiae (Baker's| yeast) Length = 345 Score = 61.6 bits (148), Expect = 7e-09 Identities = 67/281 (23%), Positives = 117/281 (41%), Gaps = 28/281 (9%) Frame = +2 Query: 356 FFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAA----LPWRFGRGSVI 523 FF+ E YG ++ R+ DV I+ K A L R V+ Sbjct: 53 FFNVGEFYGPDFINLSYVHDFFAKYPDLRK-----DVVISCKGGADNATLTPRGSHDDVV 107 Query: 524 SALKGSLSRLG-------VSSVESYQLHWPGIWGNEGYLDGLADAYEQGLVKSVGVSNYS 682 ++K S+S +G V+ +++ ++ E + + LA+ +G++ + +S + Sbjct: 108 QSVKNSVSAIGGYIDIFEVARIDTSLCTKGEVYPYESF-EALAEMISEGVIGGISLSEVN 166 Query: 683 EKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALT 862 E+++R H K G L +V SL + NG+ C ELG+++I YSP+ +G LT Sbjct: 167 EEQIRAIH---KDWGKFLTCVEVELSLFSNDILHNGIAKTCAELGLSIICYSPLGRGLLT 223 Query: 863 GKY-TPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGS-YDKTP-------TQVVLNWL 1015 G+ + A+ P G + L+ + +R + DK P Q+ L W+ Sbjct: 224 GQLKSNADIPEGDFRKSLKRFSDESLKKNLTLVRFLQEEIVDKRPQNNSITLAQLALGWV 283 Query: 1016 ICQGNV--------VPIPGAKNAEQAREFAGALGWLLTEQE 1114 V +PIP + + E LT+QE Sbjct: 284 KHWNKVPEYSGAKFIPIPSGSSISKVNENFDEQKTKLTDQE 324
>Q09632:YOF5_CAEEL Probable oxidoreductase ZK1290.5 - Caenorhabditis elegans| Length = 321 Score = 61.2 bits (147), Expect = 9e-09 Identities = 67/280 (23%), Positives = 114/280 (40%), Gaps = 9/280 (3%) Frame = +2 Query: 347 GITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGS-VI 523 G DTA+ YG E LG +K + ++ ++TK W G V Sbjct: 39 GYRLIDTAKRYGV--------EKQLGIAVKNCSVPRE-EMFLSTKL----WPVDCGDEVY 85 Query: 524 SALKGSLSRLGVSSVESYQLHWPGI--W------GNEGYLDGLADAYEQGLVKSVGVSNY 679 +A + S +L ++ Y +H P + W E + YE V+S+GVSNY Sbjct: 86 NAFQTSCEKLQTDYLDMYMIHMPQLPDWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNY 145 Query: 680 SEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGAL 859 S + D + L+ + +NQV + + +K CDELGI + Y P+A Sbjct: 146 S---IEDLDELLEFASILPHANQVELHPWFHQAD---LKNYCDELGILTMGYCPLA---- 195 Query: 860 TGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVP 1039 +G+ + L K I Y K+P Q+ L W I Q NV Sbjct: 196 -------------KGKYLEDETLCK----------IASKYQKSPAQICLRWSI-QQNVPT 231 Query: 1040 IPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVKPVM 1159 +P + + + +E + L+ +++ L S + + + ++ Sbjct: 232 VPKSTDCRRLKENTNVFDFELSAEDMNTLNSFSSQNRKIV 271
>Q12458:YPR1_YEAST Putative reductase 1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 312 Score = 60.8 bits (146), Expect = 1e-08 Identities = 79/350 (22%), Positives = 142/350 (40%), Gaps = 28/350 (8%) Frame = +2 Query: 176 AAVEDGSKAMLGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGIT 355 A +++ S + +G ++ LG G W D ++ + A++ +G Sbjct: 3 ATLKNSSATLKLNTGASIPVLGFGTWRSVDNNGYH--------------SVIAALKAGYR 48 Query: 356 FFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVISALK 535 D A +Y +N E + GR IK+ + ++ I TK W + +AL Sbjct: 49 HIDAAAIY-------LNEEEV-GRAIKDSGVPRE-EIFITTKL----WGTEQRDPEAALN 95 Query: 536 GSLSRLGVSSVESYQLHWPGIWGNEGYLDG----------------------------LA 631 SL RLG+ V+ Y +HWP + DG + Sbjct: 96 KSLKRLGLDYVDLYLMHWPVPLKTDRVTDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQ 155 Query: 632 DAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDE 811 + + G K+VGVSN+S +++ + + VP A+NQ+ I+ ++ + A C E Sbjct: 156 ELPKTGKTKAVGVSNFSINNIKELLESPNNKVVP-ATNQIE---IHPLLPQDELIAFCKE 211 Query: 812 LGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTP 991 GI + AYSP + AN P L K Q +I+ + + P Sbjct: 212 KGIVVEAYSP---------FGSANAP------------LLKEQAIIDMAK----KHGVEP 246 Query: 992 TQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAR 1141 Q++++W I +G VV AK+ R + + L E + + + ++++ Sbjct: 247 AQLIISWSIQRGYVVL---AKSVNPERIVSNFKIFTLPEDDFKTISNLSK 293
>Q8XBT6:DKGA_ECO57 2,5-diketo-D-gluconic acid reductase A - Escherichia coli O157:H7| Length = 275 Score = 60.5 bits (145), Expect = 2e-08 Identities = 72/309 (23%), Positives = 126/309 (40%), Gaps = 3/309 (0%) Frame = +2 Query: 218 GVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVSG 397 G + +LG+G W + ++ A +++ G FDTA Y Sbjct: 12 GNVMPQLGLGVWQASN--------------EEVITAIQKALEVGYRSFDTAAAY------ 51 Query: 398 AINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVISALKGSLSRLGVSSVESY 577 +E +G+ +K + ++ I TK W AL SL +L + ++ Y Sbjct: 52 --KNEEGVGKALKNASVNRE-ELFITTKL----WNDDHNRPREALLDSLKKLQLDYIDLY 104 Query: 578 QLHWPGIWGNEGYLD---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQ 748 +HWP + + Y++ G+ + ++GL+KS+GV N+ L+ D + GV NQ Sbjct: 105 LMHWP-VPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLID---ETGVTPVINQ 160 Query: 749 VNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFL 928 + + + + + A I ++SP+AQG GK F Sbjct: 161 IELHPLMQQRQLHAWNATHK---IQTESWSPLAQG---GK----------------GVFD 198 Query: 929 SKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTE 1108 K+ IR + Y KTP Q+V+ W + G VV IP + + E + L + Sbjct: 199 QKV------IRDLADKYGKTPAQIVIRWHLDSGLVV-IPKSVTPSRIAENFDVWDFRLDK 251 Query: 1109 QEVEELRSM 1135 E+ E+ + Sbjct: 252 DELGEIAKL 260
>P58744:DKGA_SALTI 2,5-diketo-D-gluconic acid reductase A - Salmonella typhi| Length = 275 Score = 60.1 bits (144), Expect = 2e-08 Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 3/309 (0%) Frame = +2 Query: 218 GVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVSG 397 G + +LG+G W + ++ A +++ G DTA Y Sbjct: 12 GNVMPQLGLGVWKASN--------------EEVIAAIHKALEVGYRSIDTATAY------ 51 Query: 398 AINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVISALKGSLSRLGVSSVESY 577 +E +G+ +K + ++ I TK W + AL+ SL +L + ++ Y Sbjct: 52 --QNEEGVGKALKAASVARE-ELFITTKL----WNDDQKRPREALQESLKKLQLDYLDLY 104 Query: 578 QLHWPGIWGNEGYLD---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQ 748 +HWP + + Y+D G+ ++GLVKS+GV N+ L+ D + GVP NQ Sbjct: 105 LMHWP-VPAIDHYVDAWKGMIALQKEGLVKSIGVCNFQIHHLQRLID---ETGVPPVINQ 160 Query: 749 VNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFL 928 + + + + + A I ++SP+AQG F Sbjct: 161 IELHPLMQQRQLHAWNATHK---IQTESWSPLAQGG-------------------EGVFD 198 Query: 929 SKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTE 1108 K+ IR + Y KTP Q+V+ W + G VV IP + + E + L + Sbjct: 199 QKV------IRELADKYGKTPAQIVIRWHLDCGLVV-IPKSVTPSRIAENFAVWDFRLDK 251 Query: 1109 QEVEELRSM 1135 E+ E+ + Sbjct: 252 DELGEIAKL 260
>P25906:YDBC_ECOLI Putative oxidoreductase ydbC - Escherichia coli| Length = 286 Score = 59.7 bits (143), Expect = 3e-08 Identities = 71/282 (25%), Positives = 111/282 (39%), Gaps = 16/282 (5%) Frame = +2 Query: 347 GITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAA--------LPWR 502 G+ DT++ YG V+ I I+E D+ I TK A LP Sbjct: 49 GVNHIDTSDFYGPHVTNQI---------IREALYPYSDDLTIVTKIGARRGEDASWLP-A 98 Query: 503 FGRGSVISALKGSLSRLGVSSVESYQL-------HWPGIWGNEGYLDGLADAYEQGLVKS 661 F + A+ +L LG+ ++ L H P E L LA+ +QGLVK Sbjct: 99 FSPAELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKH 158 Query: 662 VGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSP 841 +G+SN + ++ +A ++ + Q Y++ +R + A D L IAY P Sbjct: 159 IGLSNVTPTQVAEA-----RKIAEIVCVQNEYNIAHRADD-----AMIDALAHDGIAYVP 208 Query: 842 IAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLIC 1021 G +TP T + + S TP QV L WL+ Sbjct: 209 FFP---LGGFTPLQSST---------------------LSDVAASLGATPMQVALAWLLQ 244 Query: 1022 QG-NVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMARE 1144 + N++ IPG + RE A L+E+ + L ++RE Sbjct: 245 RSPNILLIPGTSSVAHLRENMAAEKLHLSEEVLSTLDGISRE 286
>P06632:DKGA_CORSC 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain| ATCC 31090) Length = 278 Score = 59.7 bits (143), Expect = 3e-08 Identities = 72/286 (25%), Positives = 115/286 (40%), Gaps = 11/286 (3%) Frame = +2 Query: 311 DAKGAFDASVDSGITFFDTAEVYG--AGVSGAINSESLLGRFIKERQEKEKVDVAIATKF 484 D + A + +++ G DTA +YG GV AI + + + D+ I TK Sbjct: 28 DTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAASGIA-----------RDDLFITTKL 76 Query: 485 AALPW--RFGRGSVISALKGSLSRLGVSSVESYQLHWPGIWGNEGYLDGLADAYEQ---- 646 W R +A+ SL++L + V+ Y +HWP D A+E+ Sbjct: 77 ----WNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP-----TPAADNYVHAWEKMIEL 127 Query: 647 ---GLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELG 817 GL +S+GVSN+ L + GV A NQ+ Y+ E AA D Sbjct: 128 RAAGLTRSIGVSNHLVPHLERI---VAATGVVPAVNQIELHPAYQQREITDWAAAHD--- 181 Query: 818 ITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQ 997 + + ++ P+ QG KY L +P + ++ KTP Q Sbjct: 182 VKIESWGPLGQG----KYD-----------------LFGAEP----VTAAAAAHGKTPAQ 216 Query: 998 VVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 VL W + +G VV P + E+ E + LT+ E+ + +M Sbjct: 217 AVLRWHLQKGFVV-FPKSVRRERLEENLDVFDFDLTDTEIAAIDAM 261
>Q8ZI40:DKGA_YERPE 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis| Length = 277 Score = 58.5 bits (140), Expect = 6e-08 Identities = 69/303 (22%), Positives = 125/303 (41%), Gaps = 3/303 (0%) Frame = +2 Query: 218 GVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVSG 397 G + +LG+G W +++ + A +++ G DTA +Y Sbjct: 12 GRLMPQLGLGVWQ--------------ASIQETELAVSKALEVGYRSIDTAAIY------ 51 Query: 398 AINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVISALKGSLSRLGVSSVESY 577 +E +G+ +K ++ I TK W + + AL+ SL +L + V+ Y Sbjct: 52 --KNEEGVGKALKAAAVARD-ELFITTKL----WNDDQHNPQQALETSLQKLQLDYVDLY 104 Query: 578 QLHWPGIWGNEGYLDG---LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQ 748 +HWP + Y+ L EQGL++S+GV N+ L+ D + G+ NQ Sbjct: 105 LIHWPDP-KQDHYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLID---ETGIAPTVNQ 160 Query: 749 VNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFL 928 + + + + + A I ++SP+AQG GK ++ + + Sbjct: 161 IELHPLLQQRQLHAWNATHH---IATESWSPLAQG---GK------------GVFDQEII 202 Query: 929 SKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTE 1108 KL Y+KTP Q+V+ W + G +V IP + + RE + L + Sbjct: 203 RKLAQ----------QYNKTPAQIVIRWHLDSGLIV-IPKSVTPARIRENFEVFDFKLQK 251 Query: 1109 QEV 1117 +E+ Sbjct: 252 EEL 254
>Q9DCT1:AK1E1_MOUSE Aldo-keto reductase family 1 member E1 - Mus musculus (Mouse)| Length = 301 Score = 57.8 bits (138), Expect = 1e-07 Identities = 69/301 (22%), Positives = 131/301 (43%), Gaps = 25/301 (8%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEK---EKVDVAIATKFAAL 493 A +++ G FD A +Y ++ES +G I E+ ++ ++ D+ + +K Sbjct: 22 AVKLAINLGYRHFDCAYLY--------HNESEVGMGISEKIKEGVVKREDLFVVSKLWCT 73 Query: 494 PWRFGRGSVISALKGSLSRLGVSSVESYQLHWPG-----------------IWGNEGYLD 622 + + V +A +L L + ++ Y +HWP I + +LD Sbjct: 74 CHK--KSLVKTACTNTLEALNLDYLDLYLIHWPMGFKPGEKDIPLDRNGKVIPSHTSFLD 131 Query: 623 ---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGV 793 + D +GLVK++GVSN++ ++L D+ R P+ +NQ+ +P N Sbjct: 132 TWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPI-TNQIEC-----HPYLNQK 185 Query: 794 KAA--CDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVI 967 K C + +++ AY P+ G G + D IR I Sbjct: 186 KLIDFCHKRNVSVTAYRPLG---------------GSGGGFHLMD--------DTVIRKI 222 Query: 968 GGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREV 1147 + K+P Q+++ + I Q N++ IP + + RE + LTE+++EEL S+ + + Sbjct: 223 AKKHGKSPAQILIRFQI-QRNLIVIPKSVTPSRIRENIQVFDFELTEKDMEELLSLDKNL 281 Query: 1148 K 1150 + Sbjct: 282 R 282
>Q46857:DKGA_ECOLI 2,5-diketo-D-gluconic acid reductase A - Escherichia coli| Length = 275 Score = 57.4 bits (137), Expect = 1e-07 Identities = 71/309 (22%), Positives = 125/309 (40%), Gaps = 3/309 (0%) Frame = +2 Query: 218 GVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVSG 397 G + +LG+G W + ++ A +++ G DTA Y Sbjct: 12 GNVMPQLGLGVWQASN--------------EEVITAIQKALEVGYRSIDTAAAY------ 51 Query: 398 AINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVISALKGSLSRLGVSSVESY 577 +E +G+ +K + ++ I TK W AL SL +L + ++ Y Sbjct: 52 --KNEEGVGKALKNASVNRE-ELFITTKL----WNDDHKRPREALLDSLKKLQLDYIDLY 104 Query: 578 QLHWPGIWGNEGYLD---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQ 748 +HWP + + Y++ G+ + ++GL+KS+GV N+ L+ D + GV NQ Sbjct: 105 LMHWP-VPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLID---ETGVTPVINQ 160 Query: 749 VNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFL 928 + + + + + A I ++SP+AQG GK F Sbjct: 161 IELHPLMQQRQLHAWNATHK---IQTESWSPLAQG---GK----------------GVFD 198 Query: 929 SKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTE 1108 K+ IR + Y KTP Q+V+ W + G VV IP + + E + L + Sbjct: 199 QKV------IRDLADKYGKTPAQIVIRWHLDSGLVV-IPKSVTPSRIAENFDVWDFRLDK 251 Query: 1109 QEVEELRSM 1135 E+ E+ + Sbjct: 252 DELGEIAKL 260
>Q02198:MORA_PSEPU Morphine 6-dehydrogenase - Pseudomonas putida| Length = 296 Score = 57.0 bits (136), Expect = 2e-07 Identities = 74/315 (23%), Positives = 130/315 (41%), Gaps = 3/315 (0%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVS 394 +GV + LG+G ++ ++ A +++ SG DTA Y Sbjct: 12 NGVKMPALGLGVFA--------------ASAEETASAIASAISSGYRLIDTARSY----- 52 Query: 395 GAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVISALKGSLSRLGVSSVES 574 N+E+ +G I+ ++ ++ + TK + + R + A SL RLG+ V+ Sbjct: 53 ---NNEAQVGEGIRN-SGVDRAEMFVTTKLFNCDYGYERA--LRAFDESLGRLGLDYVDL 106 Query: 575 YQLHWPGIWGNEGYLDGLA--DAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQ 748 Y LHWP N A G +++GV N+ E +L + + V A NQ Sbjct: 107 YLLHWPTKDWNATIQSWKAAEKILGDGRARAIGVCNFLEDQL---DELIAASDVVPAVNQ 163 Query: 749 VNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFL 928 + + + + A LGI A+SPI GA+ N G + Sbjct: 164 IELHPYF---AQKPLLAKNRALGIVTEAWSPIG-GAI-------NDGDG-------DNHG 205 Query: 929 SKLQPLINK-IRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLT 1105 + PL + I I ++ ++ QV+L W Q +VV IP + N E+ + + L+ Sbjct: 206 GRKHPLTDPVITTIAEAHGRSAAQVILRWHF-QNDVVAIPKSVNPERIAKNIDVFDFALS 264 Query: 1106 EQEVEELRSMAREVK 1150 + E+ +L + V+ Sbjct: 265 DAEMAQLDELDTGVR 279
>Q8ZM06:DKGA_SALTY 2,5-diketo-D-gluconic acid reductase A - Salmonella typhimurium| Length = 275 Score = 57.0 bits (136), Expect = 2e-07 Identities = 71/309 (22%), Positives = 124/309 (40%), Gaps = 3/309 (0%) Frame = +2 Query: 218 GVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVSG 397 G + +LG+G W + ++ A +++ G DTA Y Sbjct: 12 GNVMPQLGLGVWKASN--------------EEVIAAIHKALEVGYRSIDTATAY------ 51 Query: 398 AINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVISALKGSLSRLGVSSVESY 577 +E +G+ +K + ++ I TK W + AL+ SL +L + ++ Y Sbjct: 52 --QNEEGVGKALKAASVARE-ELFITTKL----WNDDQKRPREALQESLKKLQLDYLDLY 104 Query: 578 QLHWPGIWGNEGYLD---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQ 748 +HWP + + Y+D G+ ++GLVKS+GV N+ L+ D + GV NQ Sbjct: 105 LMHWP-VPAIDHYVDAWKGMIALQKEGLVKSIGVCNFQIHHLQRLID---ETGVTPVINQ 160 Query: 749 VNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFL 928 + + + + + A I ++SP+AQG F Sbjct: 161 IELHPLMQQRQLHAWNATHK---IQTESWSPLAQGG-------------------EGVFD 198 Query: 929 SKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTE 1108 K+ IR + Y KTP Q+V+ W + G VV IP + + E + L + Sbjct: 199 QKV------IRELADKYGKTPAQIVIRWHLDCGLVV-IPKSVTPSRIAENFAVWDFRLDK 251 Query: 1109 QEVEELRSM 1135 E+ E+ + Sbjct: 252 DELGEIAKL 260
>P76187:YDHF_ECOLI Oxidoreductase ydhF - Escherichia coli| Length = 298 Score = 56.6 bits (135), Expect = 2e-07 Identities = 68/296 (22%), Positives = 121/296 (40%), Gaps = 7/296 (2%) Frame = +2 Query: 272 YWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVSGAINSESL-LGRFIKERQE 448 YW W+ + + +D G+T D A++YG A E+L L ++ER E Sbjct: 21 YWRLMDWN-MSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALKLAPHLRERME 79 Query: 449 -KEKVDVAIATKFAALPWRF--GRGSVISALKGSLSRLGVSSVESYQLHWPG-IWGNEGY 616 K +A + + + R +I + + SL L ++ +H P + + Sbjct: 80 IVSKCGIATTAREENVIGHYITDRDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEV 139 Query: 617 LDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVK 796 D ++ G V+ GVSN++ + RL LA+NQV S +++ +G Sbjct: 140 ADAFKHLHQSGKVRHFGVSNFTPAQFALLQSRLP---FTLATNQVEISPVHQPLLLDGTL 196 Query: 797 AACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGS 976 +L + P+A L G GR++ D+ QPL +++ V+ Sbjct: 197 DQLQQLRV-----RPMAWSCLGG------------GRLFNDDY---FQPLRDELAVVAEE 236 Query: 977 YDK-TPTQVVLNWLI-CQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMA 1138 + + QVV W++ +PI G+ E+ R A +T Q+ +R A Sbjct: 237 LNAGSIEQVVYAWVLRLPSQPLPIIGSGKIERVRAAVEAETLKMTRQQWFRIRKAA 292
>Q9TV64:AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogenase - Oryctolagus cuniculus (Rabbit)| Length = 326 Score = 56.6 bits (135), Expect = 2e-07 Identities = 51/181 (28%), Positives = 90/181 (49%), Gaps = 2/181 (1%) Frame = +2 Query: 620 DGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKA 799 + L + GLVKS+GVSN++ ++L ++ + P+ NQV + P+ + Sbjct: 152 EALEACKDAGLVKSLGVSNFNRQQLELLLNKPGLKHKPVC-NQVECHPYFTQPK---LLK 207 Query: 800 ACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINK--IRVIGG 973 C + I ++AYSP+ T NP + TS L PL+ + +G Sbjct: 208 FCQQHDIIIVAYSPLG--------TCRNPMW-----VNTS-----LPPLLKDTLLNSLGK 249 Query: 974 SYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVKP 1153 Y KT Q+VL + + +G VV IP + N E+ +E + LTE+E++++ ++ + V+ Sbjct: 250 KYKKTAAQIVLRFNVQRG-VVVIPKSFNPERIKENFQIFDFSLTEEEMKDIEALNKNVRY 308 Query: 1154 V 1156 V Sbjct: 309 V 309
>P51857:AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogenase - Homo sapiens (Human)| Length = 326 Score = 56.6 bits (135), Expect = 2e-07 Identities = 49/170 (28%), Positives = 86/170 (50%) Frame = +2 Query: 641 EQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGI 820 + GLVKS+GVSN++ ++L ++ + P+ SNQV + P+ + C + I Sbjct: 159 DAGLVKSLGVSNFNRRQLELILNKPGLKHKPV-SNQVECHPYFTQPK---LLKFCQQHDI 214 Query: 821 TLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQV 1000 + AYSP+ ++PP L K L+N +G Y+KT Q+ Sbjct: 215 VITAYSPLGTSRNPIWVNVSSPP------------LLK-DALLNS---LGKRYNKTAAQI 258 Query: 1001 VLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 VL + I +G VV IP + N E+ +E + LTE+E++++ ++ + V+ Sbjct: 259 VLRFNIQRG-VVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVR 307
>O08782:ALD2_CRIGR Aldose reductase-related protein 2 - Cricetulus griseus (Chinese| hamster) Length = 316 Score = 55.8 bits (133), Expect = 4e-07 Identities = 70/298 (23%), Positives = 125/298 (41%), Gaps = 23/298 (7%) Frame = +2 Query: 317 KGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFA 487 K A ++D+G D A Y +E +G I+E+ +++ V D+ I +K Sbjct: 29 KEAVKVAIDAGYRHIDCAYAY--------YNEHEVGEAIQEKIKEKAVRREDLFIVSKL- 79 Query: 488 ALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWPG-----------------IWGNEGY 616 P F R + A + +L+ L + ++ Y +HWP + + Sbjct: 80 -WPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGNVLTSKITF 138 Query: 617 LDG---LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEEN 787 LD + + ++GLVK++GVSN++ ++ ++ + P+ +NQV + + Sbjct: 139 LDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPV-TNQVE---CHPYLTQE 194 Query: 788 GVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVI 967 + C GIT+ AYSP+ +P P P D KI+ I Sbjct: 195 KLIEYCHSKGITVTAYSPLG--------SPNRPWAKPEDPSLLED---------PKIKEI 237 Query: 968 GGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAR 1141 + KT QV++ + I Q NVV IP + + E + L++QE+ + R Sbjct: 238 AAKHKKTSAQVLIRFHI-QRNVVVIPKSVTPARIHENFQVFDFQLSDQEMATILGFNR 294
>P14065:GCY_YEAST Protein GCY - Saccharomyces cerevisiae (Baker's yeast)| Length = 312 Score = 54.3 bits (129), Expect = 1e-06 Identities = 79/351 (22%), Positives = 139/351 (39%), Gaps = 28/351 (7%) Frame = +2 Query: 176 AAVEDGSKAMLGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGIT 355 A + D +K + +G + ++G+G W K DA A ++ G Sbjct: 3 ATLHDSTKILSLNTGAQIPQIGLGTWQ--------------SKENDAYKAVLTALKDGYR 48 Query: 356 FFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVISALK 535 DTA +Y +E +G+ IK+ + ++ + TK W AL Sbjct: 49 HIDTAAIY--------RNEDQVGQAIKDSGVPRE-EIFVTTKL----WCTQHHEPEVALD 95 Query: 536 GSLSRLGVSSVESYQLHWPGIWG-----NEGYL------DG-----------------LA 631 SL RLG+ V+ Y +HWP NE L DG + Sbjct: 96 QSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQ 155 Query: 632 DAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDE 811 + + G K+VGVSN+S L+D + P A+NQV + P++ + C Sbjct: 156 ELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTP-AANQVEIHPLL--PQDELIN-FCKS 211 Query: 812 LGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTP 991 GI + AYSP+ ++D +P+I + I + P Sbjct: 212 KGIVVEAYSPLG----------------------STDAPLLKEPVILE---IAKKNNVQP 246 Query: 992 TQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMARE 1144 VV++W + +G VV +P + N ++ + + L+ ++ E + ++++E Sbjct: 247 GHVVISWHVQRGYVV-LPKSVNPDRIK--TNRKIFTLSTEDFEAINNISKE 294
>Q96JD6:AKCL2_HUMAN Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens| (Human) Length = 320 Score = 53.5 bits (127), Expect = 2e-06 Identities = 72/330 (21%), Positives = 131/330 (39%), Gaps = 45/330 (13%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVY------GAGVSGAINSESLLGRFIKERQEKEKVDVAIATKF 484 A ++D+G FD A Y GAG+ I ++ + D+ IATK Sbjct: 22 AVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAV-----------RREDLFIATKL 70 Query: 485 AALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWPG----------------------- 595 + + V +A + SL L ++ ++ Y +HWP Sbjct: 71 WCTCHK--KSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHP 128 Query: 596 -------------IWGNEGYLD---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRG 727 I + +LD + D GLVK++GVSN++ ++L ++ R Sbjct: 129 RVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRF 188 Query: 728 VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGR 907 PL +NQ+ + + + + C +++ AY P+ G+ G NP Sbjct: 189 KPL-TNQIE---CHPYLTQKNLISFCQSRDVSVTAYRPLG-GSCEGVDLIDNP------- 236 Query: 908 IYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGA 1087 I+ I + K+P Q+++ + I Q NV+ IPG+ +E Sbjct: 237 ---------------VIKRIAKEHGKSPAQILIRFQI-QRNVIVIPGSITPSHIKENIQV 280 Query: 1088 LGWLLTEQEVEELRSMAREVKPVMGFPVEK 1177 + LT+ +++ + S+ R ++ M FP+ K Sbjct: 281 FDFELTQHDMDNILSLNRNLRLAM-FPITK 309
>P28475:S6PD_MALDO NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica| (Apple) (Malus sylvestris) Length = 310 Score = 53.1 bits (126), Expect = 3e-06 Identities = 77/341 (22%), Positives = 133/341 (39%), Gaps = 28/341 (8%) Frame = +2 Query: 212 ASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDA-KGAFDASVDSGITFFDTAEVYGAG 388 +SG + +G+G W R KD K ++ G FD A Y Sbjct: 7 SSGYEMPVIGLGLW---------------RLEKDELKEVILNAIKIGYRHFDCAAHYK-- 49 Query: 389 VSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVISALKGSLSRLGVSSV 568 S A E+L F ++E ++ I TK W G V+ A K SL +L + + Sbjct: 50 -SEADVGEALAEAFKTGLVKRE--ELFITTKI----WNSDHGHVVEACKNSLEKLQIDYL 102 Query: 569 ESYQLHWP------------GIWGNEGYLD------------GLADAYEQGLVKSVGVSN 676 + Y +H+P + G + LD G+ GLV+S+G+SN Sbjct: 103 DLYLVHYPMPTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSN 162 Query: 677 YSEKRLRD--AHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQ 850 Y RD A+ ++K P S + R + + C + G+ A++P+ Sbjct: 163 YELFLTRDCLAYSKIK----PAVSQFETHPYFQR----DSLVKFCMKHGVLPTAHTPLG- 213 Query: 851 GALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKI-RVIGGSYDKTPTQVVLNWLICQG 1027 GA K D + PL + + + Y K+ Q+ L W I Q Sbjct: 214 GAAANK-----------------DMFGSVSPLDDPVLNDVAKKYGKSVAQICLRWGI-QR 255 Query: 1028 NVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 IP + ++ +E L + L++++++ + S+ R+ + Sbjct: 256 KTAVIPKSSKIQRLKENLEVLEFQLSDEDMQLIYSIDRKYR 296
>P30863:DKGB_ECOLI 2,5-diketo-D-gluconic acid reductase B - Escherichia coli| Length = 267 Score = 52.8 bits (125), Expect = 3e-06 Identities = 55/241 (22%), Positives = 106/241 (43%), Gaps = 6/241 (2%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPW--RFG 508 +++ G DTA++Y ++E+ +G+ I E + ++ I TK W Sbjct: 25 ALELGYRAIDTAQIY--------DNEAAVGQAIAE-SGVPRHELYITTKI----WIENLS 71 Query: 509 RGSVISALKGSLSRLGVSSVESYQLHWPGIWGN---EGYLDGLADAYEQGLVKSVGVSNY 679 + +I +LK SL +L V+ +HWP E ++ L +A +QGL + +G+SN+ Sbjct: 72 KDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKQGLTREIGISNF 131 Query: 680 SEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGAL 859 + + A + + A+NQ+ S +N + V A + GI + +Y +A Sbjct: 132 TIPLMEKAIAAVGAENI--ATNQIELSPYLQNRK---VVAWAKQHGIHITSYMTLAY--- 183 Query: 860 TGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQG-NVV 1036 G+ + +++ I ++ TP QV+L W + +G +V+ Sbjct: 184 --------------GKALKDEVIAR----------IAAKHNATPAQVILAWAMGEGYSVI 219 Query: 1037 P 1039 P Sbjct: 220 P 220
>Q8VCX1:AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogenase - Mus musculus (Mouse)| Length = 325 Score = 52.8 bits (125), Expect = 3e-06 Identities = 69/300 (23%), Positives = 128/300 (42%), Gaps = 22/300 (7%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWR 502 A ++D G D A VY ++E +G I+E+ + KV L W Sbjct: 39 AVKTAIDEGYRHIDGAYVY--------HNEHEVGEAIREKIAEGKVKREEIFYCGKL-WN 89 Query: 503 FGR--GSVISALKGSLSRLGVSSVESYQLHWPGIW--GNEGY------------------ 616 V+ AL+ +L L + ++ Y + P + G E Y Sbjct: 90 TEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFKPGKEIYPRDENGRIIYDKTNLCAT 149 Query: 617 LDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVK 796 + L + GLVKS+GVSN++ ++L ++ + P+ +NQV + + + Sbjct: 150 WEALEACKDAGLVKSLGVSNFNRRQLELILNKPGLKYKPV-TNQVECHPYF---TQTKLL 205 Query: 797 AACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGS 976 C + I ++A+SP+ ++PP + + L+ L G Sbjct: 206 KFCQQHDIVIVAHSPLGTCRNPSWVNVSSPP------LLNDELLTSL----------GKK 249 Query: 977 YDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVKPV 1156 Y+KT Q+VL + I +G +V IP + E+ +E + LTE+E++++ ++ + V+ V Sbjct: 250 YNKTQAQIVLRFNIQRG-IVVIPKSFTPERIKENFQIFDFSLTEEEMKDIDALNKNVRYV 308
>Q00049:NORA_ASPFL Norsolorinic acid reductase - Aspergillus flavus| Length = 388 Score = 52.4 bits (124), Expect = 4e-06 Identities = 70/343 (20%), Positives = 145/343 (42%), Gaps = 18/343 (5%) Frame = +2 Query: 197 KAMLGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEV 376 + + ++GV V+ L +G S+G+ W + + D +SG F D A Sbjct: 17 RILSSSAGVRVSPLCLGTMSFGNG--WKGVMGECDQATSFN-MLDTFYESGGNFIDVANF 73 Query: 377 YGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVIS---------- 526 Y G ++E +G ++ +RQ ++ ++ ++TK+ FG + S Sbjct: 74 YQGG-----DTERWVGEWMAQRQNRD--EIVLSTKYTMGYTMFGPQKIKSNYQGNHAKSL 126 Query: 527 --ALKGSLSRLGVSSVESYQLH-WPGIWGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLR 697 ++K SL +L ++ +H W E + L G V +GVS+ + Sbjct: 127 RLSVKASLQKLQTDYIDLLYVHMWDFTTSVEEVMRSLNHLVANGKVLYLGVSDTPAWLVV 186 Query: 698 DAHDRLKKRGV-PLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTG--K 868 + + G+ P + Q ++S +R+ E + + C+ G+ L + + +G + Sbjct: 187 KCNAFARANGLTPFSVYQGHWSCAFRDFERD-ILPMCESEGMGLAPWGVLGRGQFRSAEE 245 Query: 869 YTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVV-PIP 1045 ++ GP+ K + L K+ + + T + +++ + V P+ Sbjct: 246 FSREGRKMGPQDE--------KHRRLGEKLDQMAQQKNTKATSIAQAYVMHKAPYVFPVI 297 Query: 1046 GAKNAEQAREFAGALGWLLTEQEVEELRSMAREVKPV-MGFPV 1171 G + E +E ALG +L+E+E+ E+ + +P +GFP+ Sbjct: 298 GGRKVEHLKENIEALGLVLSEEEIREI----DDAEPFDVGFPM 336
>Q8NHP1:ARK74_HUMAN Aflatoxin B1 aldehyde reductase member 4 - Homo sapiens (Human)| Length = 331 Score = 52.4 bits (124), Expect = 4e-06 Identities = 59/185 (31%), Positives = 81/185 (43%), Gaps = 5/185 (2%) Frame = +2 Query: 332 ASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPW---R 502 A ++ G T DTA +Y G SE++LG + R V IATK A PW Sbjct: 34 AFLERGHTEIDTAFLYSDG-----QSETILGG-LGLRMGSSDCRVKIATK--ANPWIGNS 85 Query: 503 FGRGSVISALKGSLSRLGVSSVESYQLHWPGIWGN-EGYLDGLADAYEQGLVKSVGVSNY 679 SV S L+ SL RL V+ + LH P E L +++G +G+SNY Sbjct: 86 LKPDSVRSQLETSLKRLQCPCVDLFYLHAPDHSAPVEETLRACHQLHQEGKFVELGLSNY 145 Query: 680 SEKRLRDAHDRLKKRGVPLAS-NQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGA 856 + + + K G L + Q YS R E + G+ AY+P+A G Sbjct: 146 AAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETE-LFPYLRHFGLRFYAYNPLAGGL 204 Query: 857 LTGKY 871 LTGKY Sbjct: 205 LTGKY 209
>P16116:ALDR_BOVIN Aldose reductase - Bos taurus (Bovine)| Length = 315 Score = 52.4 bits (124), Expect = 4e-06 Identities = 66/297 (22%), Positives = 123/297 (41%), Gaps = 23/297 (7%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAAL 493 A ++D G D A VY +E+ +G ++ + +++ V D+ I +K Sbjct: 30 AVKVAIDLGYRHIDCAHVY--------QNENEVGLALQAKLQEQVVKREDLFIVSKLWCT 81 Query: 494 PWRFGRGSVISALKGSLSRLGVSSVESYQLHWPG-----------------IWGNEGYLD 622 + V A + +LS L + ++ Y +HWP I + ++D Sbjct: 82 --YHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKDFFPLDEDGNVIPSEKDFVD 139 Query: 623 ---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGV 793 + + ++GLVK++GVSN++ ++ L K G+ VN + + + Sbjct: 140 TWTAMEELVDEGLVKAIGVSNFNHLQVEKI---LNKPGLKY-KPAVNQIECHPYLTQEKL 195 Query: 794 KAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGG 973 C+ GI + AYSP+ +P P P D +I+ I Sbjct: 196 IQYCNSKGIVVTAYSPLG--------SPDRPWAKPEDPSILED---------PRIKAIAD 238 Query: 974 SYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMARE 1144 Y+KT QV++ + I Q N++ IP + E+ E + L ++++ L S R+ Sbjct: 239 KYNKTTAQVLIRFPI-QRNLIVIPKSVTPERIAENFQVFDFELDKEDMNTLLSYNRD 294
>Q00258:NORA_ASPPA Norsolorinic acid reductase - Aspergillus parasiticus| Length = 388 Score = 52.0 bits (123), Expect = 6e-06 Identities = 71/341 (20%), Positives = 144/341 (42%), Gaps = 18/341 (5%) Frame = +2 Query: 212 ASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGV 391 ++GV V+ L +G S+G+ W + + D +SG F D A Y G Sbjct: 22 SAGVRVSPLCLGTMSFGNG--WKGVMGECDQATSFN-MLDTFYESGGNFIDVANFYQGG- 77 Query: 392 SGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRGSVIS------------ALK 535 ++E +G ++ +RQ ++ ++ ++TK+ FG + S ++K Sbjct: 78 ----DTERWVGEWMAQRQNRD--EIVLSTKYTMGYTMFGPQKIKSNFQGNHAKSLRLSVK 131 Query: 536 GSLSRLGVSSVESYQLH-WPGIWGNEGYLDGLADAYEQGLVKSVGVSNYSEKRLRDAHDR 712 SL +L ++ +H W E + L G V +GVS+ + + Sbjct: 132 ASLQKLQTDYIDLLYVHMWDFTTSVEEVMRSLNHLVANGKVLYLGVSDTPAWLVVKCNAF 191 Query: 713 LKKRGV-PLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTG--KYTPAN 883 + G+ P + Q ++S +R+ E + + C+ G+ L + + +G +++ Sbjct: 192 ARANGLTPFSVYQGHWSSAFRDFERD-ILPMCESEGMGLAPWGVLGRGQFRSAEEFSREG 250 Query: 884 PPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVV-PIPGAKNA 1060 GP+ K + L K+ + + T + +++ + V P+ G + Sbjct: 251 RKMGPQDE--------KHRRLGEKLDQMAQQKNTKATSIAQAYVMHKAPYVFPVIGGRKV 302 Query: 1061 EQAREFAGALGWLLTEQEVEELRSMAREVKPV-MGFPVEKL 1180 E +E ALG +L+E+E+ E+ + +P +GFP+ L Sbjct: 303 EHLKENIEALGLVLSEEEIREI----DDAEPFDVGFPMNFL 339
>P80276:ALDR_PIG Aldose reductase - Sus scrofa (Pig)| Length = 316 Score = 51.6 bits (122), Expect = 8e-06 Identities = 67/296 (22%), Positives = 123/296 (41%), Gaps = 23/296 (7%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAAL 493 A ++D G D A VY +E+ +G ++E+ + + V D+ I +K Sbjct: 31 AVKVAIDLGYRHIDCAHVY--------QNENEVGLGLQEKLQGQVVKREDLFIVSKLWCT 82 Query: 494 PWRFGRGSVISALKGSLSRLGVSSVESYQLHWPGIW--GNEGY-LDG------------- 625 + V A + +L L + ++ Y +HWP + G + + LDG Sbjct: 83 DHE--KNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDPFPLDGDGNVVPDESDFVE 140 Query: 626 ----LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGV 793 + + ++GLVK++GVSN++ ++ L K G+ VN ++ + + Sbjct: 141 TWEAMEELVDEGLVKAIGVSNFNHLQVEKI---LNKPGLKY-KPAVNQIEVHPYLTQEKL 196 Query: 794 KAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGG 973 C GI + AYSP+ +P P P D +I+ I Sbjct: 197 IEYCKSKGIVVTAYSPLG--------SPDRPWAKPEDPSLLED---------PRIKAIAA 239 Query: 974 SYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAR 1141 Y+KT QV++ + + Q N++ IP + E+ E + L+ +++ L S R Sbjct: 240 KYNKTTAQVLIRFPM-QRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNR 294
>P15121:ALDR_HUMAN Aldose reductase - Homo sapiens (Human)| Length = 316 Score = 50.8 bits (120), Expect = 1e-05 Identities = 67/296 (22%), Positives = 121/296 (40%), Gaps = 23/296 (7%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAAL 493 A ++D G D A VY +E+ +G I+E+ ++ V ++ I +K Sbjct: 31 AVKVAIDVGYRHIDCAHVY--------QNENEVGVAIQEKLREQVVKREELFIVSKLWCT 82 Query: 494 PWRFGRGSVISALKGSLSRLGVSSVESYQLHWPG-----------------IWGNEGYLD 622 +G V A + +LS L + ++ Y +HWP + + LD Sbjct: 83 YHE--KGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILD 140 Query: 623 ---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGV 793 + + ++GLVK++G+SN++ ++ L K G+ VN + + + Sbjct: 141 TWAAMEELVDEGLVKAIGISNFNHLQVEMI---LNKPGLKY-KPAVNQIECHPYLTQEKL 196 Query: 794 KAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGG 973 C GI + AYSP+ +P P P D +I+ I Sbjct: 197 IQYCQSKGIVVTAYSPLG--------SPDRPWAKPEDPSLLED---------PRIKAIAA 239 Query: 974 SYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAR 1141 ++KT QV++ + + Q N+V IP + E+ E + L+ Q++ L S R Sbjct: 240 KHNKTTAQVLIRFPM-QRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294
>Q8X7Z7:DKGB_ECO57 2,5-diketo-D-gluconic acid reductase B - Escherichia coli O157:H7| Length = 267 Score = 50.4 bits (119), Expect = 2e-05 Identities = 54/241 (22%), Positives = 105/241 (43%), Gaps = 6/241 (2%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPW--RFG 508 +++ G DTA++Y ++E+ +G I E + ++ I TK W Sbjct: 25 ALELGYRAIDTAQIY--------DNEAAVGLAIAE-SGVPRHELYITTKI----WIENLS 71 Query: 509 RGSVISALKGSLSRLGVSSVESYQLHWPGIWGN---EGYLDGLADAYEQGLVKSVGVSNY 679 + +I +LK SL +L V+ +HWP E ++ L +A ++GL + +G+SN+ Sbjct: 72 KDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKEGLTREIGISNF 131 Query: 680 SEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGAL 859 + + A + + A+NQ+ S +N + V A + GI + +Y +A Sbjct: 132 TIPLMEKAIAAVGAENI--ATNQIELSPYLQNRK---VVAWAKQHGIHITSYMTLAY--- 183 Query: 860 TGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQG-NVV 1036 G+ + +++ I ++ TP QV+L W + +G +V+ Sbjct: 184 --------------GKALKDEVIAR----------IAAKHNATPAQVILAWAMGEGYSVI 219 Query: 1037 P 1039 P Sbjct: 220 P 220
>Q4R802:AKCL2_MACFA Aldo-keto reductase family 1 member C-like protein 2 - Macaca| fascicularis (Crab eating macaque) (Cynomolgus monkey) Length = 320 Score = 49.7 bits (117), Expect = 3e-05 Identities = 68/327 (20%), Positives = 135/327 (41%), Gaps = 42/327 (12%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAAL 493 A ++D+G F+ A Y ++E +G I+ + ++ V D+ IA+K Sbjct: 22 AVKVAIDAGYRHFNCAYFY--------HNEKEVGAGIRYKIKEGAVRREDLFIASKLWCT 73 Query: 494 PWRFGRGSVISALKGSLSRLGVSSVESYQLHWPG-------------------------- 595 + + V +A + SL L ++ ++ Y +HWP Sbjct: 74 CHK--KSLVKTACRRSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPGVH 131 Query: 596 ----------IWGNEGYLD---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPL 736 I G+ +LD + D GLVK++GVSN++ ++L ++ R P+ Sbjct: 132 DLPLDESDMVIPGDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPV 191 Query: 737 ASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYT 916 +NQ+ + + + + C G+++ AY P+ G Sbjct: 192 -TNQIE---CHPYLTQKNLISFCQSRGVSVTAYRPLG------------------GSCEG 229 Query: 917 SDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGW 1096 D + P+I + I + K+P Q+++ + Q NV+ IPG+ +E + Sbjct: 230 VDLID--DPVIQR---IAKEHSKSPAQILIRFQ-TQRNVIVIPGSITPSHIKENIQVFDF 283 Query: 1097 LLTEQEVEELRSMAREVKPVMGFPVEK 1177 LT+ +++ + S+ R ++ + FP+ K Sbjct: 284 ELTQHDMDNILSLDRNLR-LATFPITK 309
>P38918:ARK73_RAT Aflatoxin B1 aldehyde reductase member 3 - Rattus norvegicus (Rat)| Length = 327 Score = 49.3 bits (116), Expect = 4e-05 Identities = 55/186 (29%), Positives = 80/186 (43%), Gaps = 6/186 (3%) Frame = +2 Query: 332 ASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGR 511 A + G T DTA VY G S I + LG + V IATK A + FG+ Sbjct: 30 AFLQRGHTEIDTAFVYANGQSETILGDLGLGL------GRSGCKVKIATKAAPM---FGK 80 Query: 512 ----GSVISALKGSLSRLGVSSVESYQLHWPGIWGN-EGYLDGLADAYEQGLVKSVGVSN 676 V L+ SL RL V+ + LH+P E L +++G +G+SN Sbjct: 81 TLKPADVRFQLETSLKRLQCPRVDLFYLHFPDHGTPIEETLQACHQLHQEGKFVELGLSN 140 Query: 677 YSEKRLRDAHDRLKKRGVPLAS-NQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQG 853 Y + + KK G + + Q Y+ I R E + G+ A++P+A G Sbjct: 141 YVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQVETE-LFPCLRHFGLRFYAFNPLAGG 199 Query: 854 ALTGKY 871 LTG+Y Sbjct: 200 LLTGRY 205
>Q8CG45:ARK72_RAT Aflatoxin B1 aldehyde reductase member 2 - Rattus norvegicus (Rat)| Length = 367 Score = 49.3 bits (116), Expect = 4e-05 Identities = 57/189 (30%), Positives = 82/189 (43%), Gaps = 9/189 (4%) Frame = +2 Query: 332 ASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPW---R 502 A ++ G+ DTA +Y G SES+LG + V IATK A PW Sbjct: 70 AFLERGLNELDTAFMYCDG-----QSESILGSLGLGLGSGD-CTVKIATK--ANPWDGKS 121 Query: 503 FGRGSVISALKGSLSRLGVSSVESYQLHWPGIWGNEGY-----LDGLADAYEQGLVKSVG 667 SV S L+ SL RL V+ + LH P + G L +++G +G Sbjct: 122 LKPDSVRSQLETSLKRLQCPRVDLFYLHAP----DHGTPIVETLQACQQLHQEGKFVELG 177 Query: 668 VSNYSEKRLRDAHDRLKKRGVPLAS-NQVNYSLIYRNPEENGVKAACDELGITLIAYSPI 844 +SNY+ + + + K G L + Q Y+ R E + G+ AY+P+ Sbjct: 178 LSNYASWEVAEIYTLCKSNGWILPTVYQGMYNATTRQVETE-LLPCLRYFGLRFYAYNPL 236 Query: 845 AQGALTGKY 871 A G LTGKY Sbjct: 237 AGGLLTGKY 245
>P45376:ALDR_MOUSE Aldose reductase - Mus musculus (Mouse)| Length = 316 Score = 49.3 bits (116), Expect = 4e-05 Identities = 66/296 (22%), Positives = 120/296 (40%), Gaps = 23/296 (7%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAAL 493 A ++D G D A+VY +E +G ++E+ +++ V D+ I +K Sbjct: 31 AVKVAIDLGYRHIDCAQVY--------QNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCT 82 Query: 494 PWRFGRGSVISALKGSLSRLGVSSVESYQLHWPG-----------------IWGNEGYLD 622 + V A + +LS L + ++ Y +HWP I + ++D Sbjct: 83 --FHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVD 140 Query: 623 ---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGV 793 + ++GLVK++GVSN++ ++ L K G+ VN + + + Sbjct: 141 TWTAMEQLVDEGLVKTIGVSNFNPLQIERI---LNKPGLKY-KPAVNQIECHPYLTQEKL 196 Query: 794 KAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGG 973 C GI + AYSP+ +P P P D +I+ I Sbjct: 197 IEYCHSKGIVVTAYSPLG--------SPDRPWAKPEDPSLLED---------PRIKAIAA 239 Query: 974 SYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAR 1141 Y+KT QV++ + I Q N+V IP + + E + ++ +++ L S R Sbjct: 240 KYNKTTAQVLIRFPI-QRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNR 294
>P78736:XYL1_PACTA NAD(P)H-dependent D-xylose reductase - Pachysolen tannophilus (Yeast)| Length = 318 Score = 48.9 bits (115), Expect = 5e-05 Identities = 83/345 (24%), Positives = 132/345 (38%), Gaps = 33/345 (9%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYG--AG 388 +G + +G+G W KL++A A++ G FD A YG Sbjct: 10 NGRKIPAIGMGCW----------------KLENAADMVYAAIKEGYRLFDCACDYGNEKE 53 Query: 389 VSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWR--FGRGSVISALKGSLSRLGVS 562 V IN R IK+ K K D+ I +K W + +V AL SLS + Sbjct: 54 VGEGIN------RAIKDGLVKRK-DLFITSKL----WNNFHAKENVKKALMKSLSDFNLD 102 Query: 563 SVESYQLHWP--------------GIWGNEG----YLD--------GLADAYEQGLVKSV 664 + Y +H+P G + +G Y D + + ++GLVKS+ Sbjct: 103 YFDLYLMHFPISFKFVPFEEKYPPGFYCGDGDKFIYEDVPIIETWRAMENLVDEGLVKSI 162 Query: 665 GVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPI 844 GVSN S L D +K + AS Q+ + + ++N + GI + YS Sbjct: 163 GVSNVSGGLLEDL---IKAARIKPASLQIEH---HPYLQQNKLVEYAQLKGIVVTGYSNF 216 Query: 845 AQGALTGKYTPANPPTGPRGRI-YTSDFLSKLQPLINK--IRVIGGSYDKTPTQVVLNWL 1015 GP + ++ K QPL I I + KTP QV+L W Sbjct: 217 ----------------GPLSFLELGNETAKKTQPLYENKTITTIAAKHGKTPFQVLLRW- 259 Query: 1016 ICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 + Q + IP + + LT+++ EE+ + R ++ Sbjct: 260 VNQRGIAIIPKSTFPNTLAVNLHVDEFDLTKEDFEEIAKLDRHLR 304
>P47137:YJ66_YEAST Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's| yeast) Length = 282 Score = 48.5 bits (114), Expect = 6e-05 Identities = 62/273 (22%), Positives = 118/273 (43%), Gaps = 10/273 (3%) Frame = +2 Query: 338 VDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEK----EKVDVAIATKFAALPWRF 505 V G FDTA +YG N + + IK E ++ ++ TK W Sbjct: 37 VKCGYRHFDTAVLYG-------NEKEVGDGIIKWLNEDPGNHKREEIFYTTKL----WNS 85 Query: 506 GRG--SVISALKGSLSRL-GVSSVESYQLHWPGIWGNEGYLD---GLADAYEQGLVKSVG 667 G +A++ L+ + G+ ++ +H P + G++ L+ + +A ++GLVKS+G Sbjct: 86 QNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP-LEGSKLRLETWRAMQEAVDEGLVKSIG 144 Query: 668 VSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIA 847 VSNY +K + + + + + P+ NQ+ S E + C G+ + A++P+ Sbjct: 145 VSNYGKKHIDELLNWPELKHKPVV-NQIEISPWIMRQE---LADYCKSKGLVVEAFAPLC 200 Query: 848 QGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQG 1027 G Y NP D L + + D+ P QV++ W + Q Sbjct: 201 HG-----YKMTNP-----------DLLKVCKEV-----------DRNPGQVLIRWSL-QH 232 Query: 1028 NVVPIPGAKNAEQAREFAGALGWLLTEQEVEEL 1126 +P+P K ++ A + L++++++ L Sbjct: 233 GYLPLPKTKTVKRLEGNLAAYNFELSDEQMKFL 265
>Q8ZRM7:DKGB_SALTY 2,5-diketo-D-gluconic acid reductase B - Salmonella typhimurium| Length = 267 Score = 48.5 bits (114), Expect = 6e-05 Identities = 54/241 (22%), Positives = 103/241 (42%), Gaps = 6/241 (2%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPW--RFG 508 +++ G DTA++Y ++E+ +G+ I E ++ I TK W Sbjct: 25 ALELGYRAVDTAQIY--------DNEAAVGQAIAESGVPRN-ELYITTKI----WIENLS 71 Query: 509 RGSVISALKGSLSRLGVSSVESYQLHWPG---IWGNEGYLDGLADAYEQGLVKSVGVSNY 679 + +I +LK SL +L V+ +HWP E ++ L +A +QGL + +G+SN+ Sbjct: 72 KDKLIPSLKESLKKLRTDYVDLTLIHWPSPGDAVSVEEFMQALLEAKKQGLTREIGISNF 131 Query: 680 SEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGAL 859 + + A + + A+NQ+ S +N + V GI + +Y +A Sbjct: 132 TIPLMEKAIAAVGADNI--ATNQIELSPYLQNRK---VVDWAKAHGIHITSYMTLAY--- 183 Query: 860 TGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQG-NVV 1036 G+ + +++ I ++ TP QV+L W + +G +V+ Sbjct: 184 --------------GKALKDEVIAR----------IAAKHNATPAQVILAWAMGEGYSVI 219 Query: 1037 P 1039 P Sbjct: 220 P 220
>O43488:ARK72_HUMAN Aflatoxin B1 aldehyde reductase member 2 - Homo sapiens (Human)| Length = 359 Score = 47.8 bits (112), Expect = 1e-04 Identities = 58/188 (30%), Positives = 80/188 (42%), Gaps = 5/188 (2%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPW- 499 A A ++ G T DTA +Y G S I LG + + K IATK A PW Sbjct: 59 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK------IATK--ANPWD 110 Query: 500 --RFGRGSVISALKGSLSRLGVSSVESYQLHWPGIWGN-EGYLDGLADAYEQGLVKSVGV 670 SV S L+ SL RL V+ + LH P E L +++G +G+ Sbjct: 111 GKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGL 170 Query: 671 SNYSEKRLRDAHDRLKKRGVPLAS-NQVNYSLIYRNPEENGVKAACDELGITLIAYSPIA 847 SNY+ + + K G L + Q Y+ R E + G+ AY+P+A Sbjct: 171 SNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETE-LFPCLRHFGLRFYAYNPLA 229 Query: 848 QGALTGKY 871 G LTGKY Sbjct: 230 GGLLTGKY 237
>P07943:ALDR_RAT Aldose reductase - Rattus norvegicus (Rat)| Length = 316 Score = 47.8 bits (112), Expect = 1e-04 Identities = 67/296 (22%), Positives = 120/296 (40%), Gaps = 23/296 (7%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAAL 493 A ++D G D A+VY +E +G ++E+ +++ V D+ I +K Sbjct: 31 AVKVAIDMGYRHIDCAQVY--------QNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCT 82 Query: 494 PWRFGRGSVISALKGSLSRLGVSSVESYQLHWPG-----------------IWGNEGYLD 622 + V A + +LS L + ++ Y +HWP I + ++D Sbjct: 83 --FHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVD 140 Query: 623 ---GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGV 793 + ++GLVK++GVSN++ ++ L K G+ VN + + + Sbjct: 141 TWTAMEQLVDEGLVKAIGVSNFNPLQIERI---LNKPGLKY-KPAVNQIECHPYLTQEKL 196 Query: 794 KAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGG 973 C GI + AYSP+ +P P P D +I+ I Sbjct: 197 IEYCHCKGIVVTAYSPLG--------SPDRPWAKPEDPSLLED---------PRIKEIAA 239 Query: 974 SYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAR 1141 Y+KT QV++ + I Q N+V IP + + E + L+ +++ L S R Sbjct: 240 KYNKTTAQVLIRFPI-QRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNR 294
>P42972:YCSN_BACSU Uncharacterized oxidoreductase ycsN - Bacillus subtilis| Length = 300 Score = 47.4 bits (111), Expect = 1e-04 Identities = 63/287 (21%), Positives = 119/287 (41%), Gaps = 8/287 (2%) Frame = +2 Query: 278 NDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVSGAINSESL-LGRFIKERQE-K 451 N++ + D +L + +D GIT FD A++YG + +L L ++E E Sbjct: 23 NEWNYSDAELLSL---IEWCIDHGITTFDHADIYGGYTCEKLFGNALALSPGLRENIELV 79 Query: 452 EKVDVAIAT----KFAALPWRFGRGSVISALKGSLSRLGVSSVESYQLHWPG-IWGNEGY 616 K + + + + + + ++++++ SL L ++ +H P + EG Sbjct: 80 TKCGIVLESPERPAHRSHHYNTSKSHILASVEQSLMNLRTDYIDMLLIHRPDPLMDPEGV 139 Query: 617 LDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVK 796 + G V+ GVSN+ + + R L ++ L +NQ+ S +G Sbjct: 140 AEAFQALKCSGKVRYFGVSNFKDHQYRMLESYLPEK---LVTNQIELSAYELENMLDGTL 196 Query: 797 AACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGS 976 C E I +A+SP+A G + + T + R+ T+ L +Q I S Sbjct: 197 NLCQEKRIPPMAWSPLAGGKVFTENTDKD------RRVRTA--LESVQGEIG-----AAS 243 Query: 977 YDKTPTQVVLNWLICQ-GNVVPIPGAKNAEQAREFAGALGWLLTEQE 1114 D +V+ WL ++PI G+ E+ AL + L + + Sbjct: 244 LD----EVMYAWLYTHPAGIMPIVGSGKRERISAAINALSYKLDQDQ 286
>P31210:AK1D1_RAT 3-oxo-5-beta-steroid 4-dehydrogenase - Rattus norvegicus (Rat)| Length = 326 Score = 47.4 bits (111), Expect = 1e-04 Identities = 69/298 (23%), Positives = 125/298 (41%), Gaps = 22/298 (7%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWR 502 A ++D G D A VY +E +G I+E+ + KV L W Sbjct: 39 AVKTAIDEGYRHIDGAYVY--------RNEHEVGEAIREKVAEGKVKREEIFYCGKL-WS 89 Query: 503 FGRGS--VISALKGSLSRLGVSSVESYQLHWPGIW--GNEGY------------------ 616 V AL+ +L L + ++ Y + P + G E Y Sbjct: 90 TDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFKPGEEFYPKDENGRVIYHKSNLCAT 149 Query: 617 LDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVK 796 + L + GLVKS+GVSN++ ++L ++ + P+ +NQV + + V Sbjct: 150 WEALEACKDAGLVKSLGVSNFNRRQLEVILNKPGLKYKPV-TNQVECHPYFTQTKLLEVS 208 Query: 797 AACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGS 976 A+ + ++AYSP+ ++PP + + L+ L G Sbjct: 209 AS--SMTSFIVAYSPLGTCRNPLWVNVSSPP------LLKDELLTSL----------GKK 250 Query: 977 YDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 Y+KT Q+VL + I +G VV IP + E+ +E + LT++E++++ ++ + V+ Sbjct: 251 YNKTQAQIVLRFDIQRGLVV-IPKSTTPERIKENFQIFDFSLTKEEMKDIEALNKNVR 307
>Q8Z988:DKGB_SALTI 2,5-diketo-D-gluconic acid reductase B - Salmonella typhi| Length = 267 Score = 47.0 bits (110), Expect = 2e-04 Identities = 57/242 (23%), Positives = 104/242 (42%), Gaps = 7/242 (2%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPW--RFG 508 +++ G DTA++Y ++E+ +G+ I E ++ I TK W Sbjct: 25 ALELGYRAVDTAQIY--------DNEAAVGQAIAESGVPRN-ELYITTKI----WIENLS 71 Query: 509 RGSVISALKGSLSRLGVSSVESYQLHWPG---IWGNEGYLDGLADAYEQGLVKSVGVSNY 679 + +I +LK SL +L V+ +HWP E ++ L +A +QGL + +G+SN+ Sbjct: 72 KDKLIPSLKESLKKLRTDYVDLTLIHWPSPGDAVSVEEFMQALLEAKKQGLTREIGISNF 131 Query: 680 SEKRLRDAHDRLKKRGVP-LASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGA 856 + + A + G +A+NQ+ S +N + V GI + +Y +A G Sbjct: 132 TIPLMEKA---IAAVGADHIATNQIELSPYLQNRK---VVDWAKAHGIHITSYMTLAYGK 185 Query: 857 LTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQG-NV 1033 + +I +I V ++ TP QV+L W + +G +V Sbjct: 186 ------------------------ALKDEVIARIAV---KHNATPVQVILAWAMGEGYSV 218 Query: 1034 VP 1039 +P Sbjct: 219 IP 220
>O13283:XYL1_CANTR NAD(P)H-dependent D-xylose reductase I,II - Candida tropicalis| (Yeast) Length = 324 Score = 46.6 bits (109), Expect = 2e-04 Identities = 76/340 (22%), Positives = 133/340 (39%), Gaps = 33/340 (9%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYG--AG 388 SG + +G G W + T A ++ +G FD AE YG Sbjct: 14 SGYEMPLVGFGCWKVTNAT--------------AADQIYNAIKTGYRLFDGAEDYGNEKE 59 Query: 389 VSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWR--FGRGSVISALKGSLSRLGVS 562 V IN R IKE K + ++ I +K W +V +AL +LS L + Sbjct: 60 VGEGIN------RAIKEGLVKRE-ELFITSKL----WNNFHDPKNVETALNKTLSDLNLD 108 Query: 563 SVESYQLHWP--------------GIWGNEG----YLD--------GLADAYEQGLVKSV 664 V+ + +H+P G + +G Y D L E G +KS+ Sbjct: 109 YVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFHYEDVPLLDTWKALEKLVEAGKIKSI 168 Query: 665 GVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPI 844 G+SN++ + +D ++ + A Q+ + + P+ LI Y Sbjct: 169 GISNFTGALI---YDLIRGATIKPAVLQIEHHPYLQQPK--------------LIEYVQK 211 Query: 845 AQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLI---NKIRVIGGSYDKTPTQVVLNWL 1015 A A+TG + GP+ + + P + I++I + K+P QV+L W Sbjct: 212 AGIAITGYSS-----FGPQSFLELESKRALNTPTLFEHETIKLIADKHGKSPAQVLLRW- 265 Query: 1016 ICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 Q N+ IP + N E+ + + + LT+ +++ + + Sbjct: 266 ATQRNIAVIPKSNNPERLAQNLSVVDFDLTKDDLDNIAKL 305
>Q8CG76:ARK72_MOUSE Aflatoxin B1 aldehyde reductase member 2 - Mus musculus (Mouse)| Length = 367 Score = 46.2 bits (108), Expect = 3e-04 Identities = 57/186 (30%), Positives = 82/186 (44%), Gaps = 6/186 (3%) Frame = +2 Query: 332 ASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGR 511 A ++ G + DTA +Y G SE++LG + V IATK A PW G+ Sbjct: 70 AFLERGHSELDTAFMYCDG-----QSENILGGLGLGLGSGD-CTVKIATK--ANPWE-GK 120 Query: 512 G----SVISALKGSLSRLGVSSVESYQLHWPG-IWGNEGYLDGLADAYEQGLVKSVGVSN 676 SV S L+ SL RL V+ + LH P E L +++G +G+SN Sbjct: 121 SLKPDSVRSQLETSLKRLQCPRVDLFYLHAPDHSTPVEETLRACHQLHQEGKFVELGLSN 180 Query: 677 YSEKRLRDAHDRLKKRGVPLAS-NQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQG 853 Y+ + + K G L + Q Y+ R E + G+ AY+P+A G Sbjct: 181 YASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVEAE-LLPCLRHFGLRFYAYNPLAGG 239 Query: 854 ALTGKY 871 LTGKY Sbjct: 240 LLTGKY 245
>P87039:XYL2_CANTR NADPH-dependent D-xylose reductase II,III - Candida tropicalis| (Yeast) Length = 324 Score = 45.8 bits (107), Expect = 4e-04 Identities = 76/340 (22%), Positives = 132/340 (38%), Gaps = 33/340 (9%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYG--AG 388 SG + +G G W + T A ++ +G FD AE YG Sbjct: 14 SGYEMPLVGFGCWKVNNET--------------AADQIYNAIKTGYRLFDGAEDYGNEKE 59 Query: 389 VSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWR--FGRGSVISALKGSLSRLGVS 562 V IN R IKE K + ++ I +K W +V +AL +LS L + Sbjct: 60 VGEGIN------RAIKEGLVKRE-ELFITSKL----WNNFHDPKNVETALNKTLSDLNLD 108 Query: 563 SVESYQLHWP--------------GIWGNEG----YLD--------GLADAYEQGLVKSV 664 V+ + +H+P G + +G Y D L E G +KS+ Sbjct: 109 YVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFHYEDVPLLDTWKALEKLVEAGKIKSI 168 Query: 665 GVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPI 844 G+SN++ + +D ++ + A Q+ + + P+ LI Y Sbjct: 169 GISNFTGALI---YDLIRGATIKPAVLQIEHHPYLQQPK--------------LIEYVQK 211 Query: 845 AQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLI---NKIRVIGGSYDKTPTQVVLNWL 1015 A A+TG + GP+ + + P + I+ I + K+P QV+L W Sbjct: 212 AGIAITGYSS-----FGPQSFLELESKRALNTPTLFEHETIKSIADKHGKSPAQVLLRW- 265 Query: 1016 ICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 Q N+ IP + N E+ + + + LT+ +++ + + Sbjct: 266 ATQRNIAVIPKSNNPERLAQNLSVVDFDLTKDDLDNIAKL 305
>O95154:ARK73_HUMAN Aflatoxin B1 aldehyde reductase member 3 - Homo sapiens (Human)| Length = 331 Score = 45.8 bits (107), Expect = 4e-04 Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 6/186 (3%) Frame = +2 Query: 332 ASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGR 511 A ++ G T DTA VY G SE++LG + R V I TK L FG Sbjct: 34 AFLERGHTEIDTAFVYSEG-----QSETILGG-LGLRLGGSDCRVKIDTKAIPL---FGN 84 Query: 512 G----SVISALKGSLSRLGVSSVESYQLHWPG-IWGNEGYLDGLADAYEQGLVKSVGVSN 676 S+ L+ SL RL V+ + LH P E L +++G +G+SN Sbjct: 85 SLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSN 144 Query: 677 YSEKRLRDAHDRLKKRGVPLAS-NQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQG 853 Y+ + + K G L + Q Y+ I R E + G+ A++P+A G Sbjct: 145 YAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETE-LFPCLRHFGLRFYAFNPLAGG 203 Query: 854 ALTGKY 871 LTGKY Sbjct: 204 LLTGKY 209
>P15122:ALDR_RABIT Aldose reductase - Oryctolagus cuniculus (Rabbit)| Length = 316 Score = 45.4 bits (106), Expect = 5e-04 Identities = 67/299 (22%), Positives = 122/299 (40%), Gaps = 26/299 (8%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAAL 493 A ++D G D A VY +E+ +G ++E+ +++ V ++ I +K Sbjct: 31 AVKTAIDLGYRHIDCAHVY--------QNENEVGVALQEKLKEQVVKREELFIVSKLWCT 82 Query: 494 PWRFGRGSVISALKGSLSRLGVSSVESYQLHWPGIW--GNEGY----------------- 616 + V A + +L+ L + ++ Y +HWP + G+E + Sbjct: 83 S--HDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGSEYFPLDAAGNVIPSDTDFLD 140 Query: 617 ----LDGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEE 784 ++GL D +GLVKS+GVSN++ ++ L K G+ VN + + Sbjct: 141 TWEAMEGLVD---EGLVKSIGVSNFNHLQIERI---LNKPGLKY-KPAVNQIECHPYLTQ 193 Query: 785 NGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRV 964 + C GI + AYSP+ +P P P D +I+ Sbjct: 194 EKLIQYCHSKGIVVTAYSPLG--------SPDRPWAKPEDPSLLED---------PRIKA 236 Query: 965 IGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAR 1141 I + KT QV++ + + Q N+V IP + + E + L+ +++ L S R Sbjct: 237 IADKHKKTTAQVLIRFPM-QRNLVVIPKSVTPARIAENFQVFDFELSSEDMTTLLSYNR 294
>Q76KC2:PLD_MICLT Pyridoxal 4-dehydrogenase - Microbacterium luteolum (Aureobacterium| luteolum) Length = 342 Score = 44.7 bits (104), Expect = 0.001 Identities = 29/92 (31%), Positives = 43/92 (46%) Frame = +2 Query: 197 KAMLGASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEV 376 K LG +G+ VT LG+G G + DA +A DSGI +FD+A + Sbjct: 8 KRALGRTGLTVTALGLGTAPLGGL-------YAPVSRADADALLEAGWDSGIRYFDSAPM 60 Query: 377 YGAGVSGAINSESLLGRFIKERQEKEKVDVAI 472 YG G E LLG ++E+ E+ + + Sbjct: 61 YGYG-----RCEHLLGDMLREKPERAVISTKV 87
>Q9JII6:AK1A1_MOUSE Alcohol dehydrogenase [NADP+] - Mus musculus (Mouse)| Length = 325 Score = 44.7 bits (104), Expect = 0.001 Identities = 62/295 (21%), Positives = 121/295 (41%), Gaps = 22/295 (7%) Frame = +2 Query: 317 KGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALP 496 K A ++ +G D A VYG +E+ +G +KE K + Sbjct: 30 KAAIKHALSAGYRHIDCASVYG--------NETEIGEALKESVGSGKAVPREELFVTSKL 81 Query: 497 W--RFGRGSVISALKGSLSRLGVSSVESYQLHWPGIW--GNEGY---LDG---------- 625 W + V AL+ +L+ L + ++ Y +HWP + G+ + DG Sbjct: 82 WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVRYDSTHYK 141 Query: 626 -----LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENG 790 L +GLVK++G+SN++ +++ D L V A QV + +N Sbjct: 142 ETWKALEVLVAKGLVKALGLSNFNSRQIDDV---LSVASVRPAVLQVE---CHPYLAQNE 195 Query: 791 VKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIG 970 + A C G+ + AYSP+ ++ P P + +P+ + + Sbjct: 196 LIAHCHARGLEVTAYSPLGSSDRAWRH-PDEP-------------VLLEEPV---VLALA 238 Query: 971 GSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 + ++P Q++L W + Q V+ IP + N + + + + +E+++L ++ Sbjct: 239 EKHGRSPAQILLRWQV-QRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDAL 292
>O74237:XYL1_CANTE NAD(P)H-dependent D-xylose reductase - Candida tenuis (Yeast)| Length = 322 Score = 44.3 bits (103), Expect = 0.001 Identities = 73/341 (21%), Positives = 131/341 (38%), Gaps = 33/341 (9%) Frame = +2 Query: 212 ASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGV 391 +SG + +G G W + T A ++ +G FD AE YG Sbjct: 11 SSGHLMPSIGFGCWKLANAT--------------AGEQVYQAIKAGYRLFDGAEDYG--- 53 Query: 392 SGAINSESLLGRFIKERQEK---EKVDVAIATKFAALPWR--FGRGSVISALKGSLSRLG 556 +E +G +K ++ ++ ++ + +K W +V +AL +L+ L Sbjct: 54 -----NEKEVGDGVKRAIDEGLVKREEIFLTSKL----WNNYHDPKNVETALNKTLADLK 104 Query: 557 VSSVESYQLHWP--------------GIWGNEG----YLD--------GLADAYEQGLVK 658 V V+ + +H+P G + +G Y D L G +K Sbjct: 105 VDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIK 164 Query: 659 SVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYS 838 S+GVSN+ L D L+ + A QV + + P+ + + G+T+ AYS Sbjct: 165 SIGVSNFPGALLLDL---LRGATIKPAVLQVEHHPYLQQPK---LIEFAQKAGVTITAYS 218 Query: 839 PIAQGALT--GKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNW 1012 + + N PT ++ D I+ I Y+KTP +V+L W Sbjct: 219 SFGPQSFVEMNQGRALNTPT-----LFAHD----------TIKAIAAKYNKTPAEVLLRW 263 Query: 1013 LICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 Q + IP + E+ + + LT+++ EE+ + Sbjct: 264 -AAQRGIAVIPKSNLPERLVQNRSFNTFDLTKEDFEEIAKL 303
>P50578:AK1A1_PIG Alcohol dehydrogenase [NADP+] - Sus scrofa (Pig)| Length = 325 Score = 44.3 bits (103), Expect = 0.001 Identities = 47/228 (20%), Positives = 102/228 (44%), Gaps = 20/228 (8%) Frame = +2 Query: 527 ALKGSLSRLGVSSVESYQLHWPGIWGN---------EGYLDGLADAYE-----------Q 646 AL+ +L+ L + ++ Y +HWP + +G + A Y+ + Sbjct: 94 ALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTIRYDATHYKDTWKALEALVAK 153 Query: 647 GLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITL 826 GLV+++G+SN+S +++ D L V A QV + +N + A C G+ + Sbjct: 154 GLVRALGLSNFSSRQIDDV---LSVASVRPAVLQVE---CHPYLAQNELIAHCQARGLEV 207 Query: 827 IAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVL 1006 AYSP+ G+ + N P + +P+ ++ + Y+++P Q++L Sbjct: 208 TAYSPL--GSSDRAWRDPNEP------------VLLEEPV---VQALAEKYNRSPAQILL 250 Query: 1007 NWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 W + Q V+ IP + + + + + +E+++L ++ + ++ Sbjct: 251 RWQV-QRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALNKNLR 297
>Q9P8R5:XYL1_ASPNG NAD(P)H-dependent D-xylose reductase - Aspergillus niger| Length = 319 Score = 43.5 bits (101), Expect = 0.002 Identities = 41/173 (23%), Positives = 77/173 (44%), Gaps = 3/173 (1%) Frame = +2 Query: 641 EQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGI 820 ++ L +S+G+SN+S + + D + R L Y R E + G+ Sbjct: 156 DKKLARSIGISNFSAQLVMDLLRYARIRPATLQIEHHPYLTQTRLVEY------AQKEGL 209 Query: 821 TLIAYS---PIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTP 991 T+ AYS P++ L+ + +PP F +L ++ I + +TP Sbjct: 210 TVTAYSSFGPLSFLELSVQNAVDSPPL----------FEHQL------VKSIAEKHGRTP 253 Query: 992 TQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 QV+L W +G V IP + N ++ ++ GW L E+E++ + + R ++ Sbjct: 254 AQVLLRWATQRGIAV-IPKSNNPQRLKQNLDVTGWNLEEEEIKAISGLDRGLR 305
>P27800:ALDX_SPOSA Aldehyde reductase 1 - Sporobolomyces salmonicolor| Length = 323 Score = 43.5 bits (101), Expect = 0.002 Identities = 61/261 (23%), Positives = 101/261 (38%), Gaps = 27/261 (10%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRG 514 ++++G D A+VY +++ +G IKE K + D+ I +K W Sbjct: 35 AIETGYRHLDLAKVY--------SNQPEVGAAIKEAGVKRE-DLFITSKL----WNNSHR 81 Query: 515 --SVISALKGSLSRLGVSSVESYQLHWPGIWGNEGYLD------------------GLAD 634 V AL +L LG+ ++ Y +HWP + EG + L D Sbjct: 82 PEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGDITQNLFPKANDKEVKLDLEVSLVD 141 Query: 635 AY-------EQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGV 793 + + G VK++GVSN+ K + DA ++ GV + NQ+ + PE + Sbjct: 142 TWKAMVKLLDTGKVKAIGVSNFDAKMV-DA--IIEATGVTPSVNQIERHPLLLQPE---L 195 Query: 794 KAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGG 973 A I + AYSP+ + +P +I+ I Sbjct: 196 IAHHKAKNIHITAYSPLGNNTVGAPLLVQHP----------------------EIKRIAE 233 Query: 974 SYDKTPTQVVLNWLICQGNVV 1036 TP QV++ W I G+ V Sbjct: 234 KNGCTPAQVLIAWAIVGGHSV 254
>Q8ZH36:DKGB_YERPE 2,5-diketo-D-gluconic acid reductase B - Yersinia pestis| Length = 267 Score = 43.1 bits (100), Expect = 0.003 Identities = 52/237 (21%), Positives = 98/237 (41%), Gaps = 6/237 (2%) Frame = +2 Query: 347 GITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPW--RFGRGSV 520 G DTA++Y +E+ +G+ I+E + ++ I TK W + + Sbjct: 29 GYRAIDTAQIY--------ENEAPVGQAIQE-SGINRDELFITTKI----WIANLSKDKL 75 Query: 521 ISALKGSLSRLGVSSVESYQLHWPGIWGNEG---YLDGLADAYEQGLVKSVGVSNYSEKR 691 I +L+ S+ +L V+ +HWP ++ L A GL + +G+SN++ Sbjct: 76 IPSLRESIQKLKTDYVDLTLIHWPSPNDEVSVAEFMSELLKAKGLGLTRQIGISNFTIDL 135 Query: 692 LRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALTGKY 871 ++ A + +A+NQ+ S + +N V + GI + +Y +A G Sbjct: 136 MKQAIAAVGAE--EIATNQIELSPLLQN---RNVVDFAKQNGIAVTSYMTLAYGK----- 185 Query: 872 TPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNWLICQG-NVVP 1039 + +P+ I+ I + TP QV+L+W + G V+P Sbjct: 186 -------------------ALAEPV---IKTIAEQHGATPAQVILSWAMQLGYGVIP 220
>P17264:CRO_RANCA Rho crystallin - Rana catesbeiana (Bull frog)| Length = 324 Score = 43.1 bits (100), Expect = 0.003 Identities = 51/237 (21%), Positives = 99/237 (41%), Gaps = 22/237 (9%) Frame = +2 Query: 503 FGRGSVISALKGSLSRLGVSSVESYQLHWPGIWGNEGYLD-------------------- 622 F V L+ SL +G+ ++ + +HWP G D Sbjct: 91 FSPDMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASDPSDKDKPFIYDNVDLCATWE 150 Query: 623 GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAA 802 L + GLV+S+GVSN++ ++L ++ + P+ NQV +Y N +N + + Sbjct: 151 ALEARKDAGLVRSLGVSNFNRRQLERILNKPGLKYKPVC-NQVECH-VYLN--QNKLHSY 206 Query: 803 CDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKL--QPLINKIRVIGGS 976 C I L+ YS + R R + L L P++NK I Sbjct: 207 CKSKDIVLVTYSVLG---------------SHRDRNWVDLSLPVLLDDPILNK---IAAK 248 Query: 977 YDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREV 1147 Y++T +V + +++ +G +V + + + ++ G + L ++++ L S+ R + Sbjct: 249 YNRTSAEVAMRFILQKG-IVVLAKSFTPARIKQNLGVFEFELKPEDMKTLESLDRNL 304
>P02532:CRO_RANTE Rho crystallin - Rana temporaria (European common frog)| Length = 324 Score = 42.4 bits (98), Expect = 0.005 Identities = 49/237 (20%), Positives = 99/237 (41%), Gaps = 22/237 (9%) Frame = +2 Query: 503 FGRGSVISALKGSLSRLGVSSVESYQLHWPGIWGNEGYLD-------------------- 622 F V L+ SL +G+ ++ + +HWP G D Sbjct: 91 FSPEMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASDPSDKDKPFIYDNVDLCATWE 150 Query: 623 GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAA 802 L + GLV+S+GVSN++ ++L ++ + P+ NQV +Y N +N + + Sbjct: 151 ALEARKDAGLVRSLGVSNFNRRQLERILNKPGLKYKPVC-NQVECH-VYLN--QNKLHSY 206 Query: 803 CDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKL--QPLINKIRVIGGS 976 C I L+ YS + R R + L L P++NK + Sbjct: 207 CKSKDIVLVTYSVLG---------------SHRDRNWVDLSLPVLLDDPILNK---VAAK 248 Query: 977 YDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREV 1147 Y++T ++ + +++ +G +V + + + ++ G + L ++++ L S+ R + Sbjct: 249 YNRTSAEIAMRFILQKG-IVVLAKSFTPARIKQNLGVFEFELKPEDMKSLESLDRNL 304
>Q8VC28:AK1CD_MOUSE Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse)| Length = 323 Score = 42.4 bits (98), Expect = 0.005 Identities = 66/297 (22%), Positives = 123/297 (41%), Gaps = 25/297 (8%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAG--VSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFG 508 ++D G DTA Y + AI S+ G +E D+ I TK +R Sbjct: 41 ALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVVKRE-------DLFITTKLWCTCFR-- 91 Query: 509 RGSVISALKGSLSRLGVSSVESYQLHWP-----------------GIWGNEGYLDG---L 628 V AL+ SL +L + V+ Y +H+P + + D L Sbjct: 92 PELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERL 151 Query: 629 ADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACD 808 + + GLVKS+GVSN++ ++L ++ + P+ NQV L Y N + + C+ Sbjct: 152 EECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVC-NQVECHL-YLN--QRKLLDYCE 207 Query: 809 ELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRV---IGGSY 979 I L+AY + T +Y +++ + P++ V + Sbjct: 208 SKDIVLVAYGALG----TQRY---------------KEWVDQNSPVLLNDPVLCDVAKKN 248 Query: 980 DKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 ++P + L +LI +G +VP+ + + RE G+ L+ ++++ L + + + Sbjct: 249 KRSPALIALRYLIQRG-IVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFR 304
>P70694:DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 - Mus musculus (Mouse)| Length = 323 Score = 42.0 bits (97), Expect = 0.006 Identities = 72/314 (22%), Positives = 129/314 (41%), Gaps = 31/314 (9%) Frame = +2 Query: 314 AKGAFDASVDSGITFFDTAEVYG--AGVSGAINSESLLGRFIKERQEKEKVDVAIATKFA 487 A A ++D+G D+A +Y V AI S+ G +E D+ +K Sbjct: 34 ATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTVKRE-------DIFYTSKV- 85 Query: 488 ALPW-RFGRGSVISA-LKGSLSRLGVSSVESYQLHWP-GIWGNEGYLD------------ 622 W F R ++ L+ SL +L + V+ Y +H+P + E YL Sbjct: 86 ---WCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKPGENYLPKDENGKLIYDAV 142 Query: 623 GLADAYEQ-------GLVKSVGVSNYSEKRLRDAHDRLKKRGVPL--ASNQVNYSLIYRN 775 + D +E GL KS+GVSN++ ++L LKK G+ NQV + Sbjct: 143 DICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKI---LKKPGLKYKPVCNQVEC-----H 194 Query: 776 PEENGVKAA--CDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLI 949 P N K C I L+AYS + G ++ + P++ Sbjct: 195 PYLNQGKLLDFCRSKDIVLVAYSAL-------------------GSHREKQWVDQSSPVL 235 Query: 950 NKIRVIGG---SYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVE 1120 V+G Y++TP + L + + +G VV + + + ++ +E + LT ++++ Sbjct: 236 LDNPVLGSMAKKYNRTPALIALRYQLQRG-VVVLAKSFSEKRIKENMQVFEFQLTSEDMK 294 Query: 1121 ELRSMAREVKPVMG 1162 L + + ++ + G Sbjct: 295 VLDDLNKNIRYISG 308
>P51635:AK1A1_RAT Alcohol dehydrogenase [NADP+] - Rattus norvegicus (Rat)| Length = 325 Score = 41.6 bits (96), Expect = 0.008 Identities = 61/295 (20%), Positives = 119/295 (40%), Gaps = 22/295 (7%) Frame = +2 Query: 317 KGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALP 496 K A ++ G D A VYG +E+ +G +KE K + Sbjct: 30 KAAIKYALSVGYRHIDCASVYG--------NETEIGEALKESVGAGKAVPREELFVTSKL 81 Query: 497 W--RFGRGSVISALKGSLSRLGVSSVESYQLHWPGIW--GNEGY---LDG---------- 625 W + V A++ +L+ L + ++ Y +HWP + G+ + DG Sbjct: 82 WNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVKYDSTHYK 141 Query: 626 -----LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENG 790 L +GLVK++G+SN+S +++ D L V A QV + +N Sbjct: 142 ETWKALEALVAKGLVKALGLSNFSSRQIDDV---LSVASVRPAVLQVE---CHPYLAQNE 195 Query: 791 VKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIG 970 + A C G+ + AYSP+ ++ P P + +P+ + + Sbjct: 196 LIAHCQARGLEVTAYSPLGSSDRAWRH-PDEP-------------VLLEEPV---VLALA 238 Query: 971 GSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 + ++P Q++L W + Q V+ IP + + + + + +E+++L ++ Sbjct: 239 EKHGRSPAQILLRWQV-QRKVICIPKSITPSRILQNIQVFDFTFSPEEMKQLDAL 292
>Q876L8:XYL1_TRIRE NAD(P)H-dependent D-xylose reductase - Trichoderma reesei (Hypocrea| jecorina) Length = 324 Score = 39.7 bits (91), Expect = 0.030 Identities = 46/197 (23%), Positives = 82/197 (41%), Gaps = 13/197 (6%) Frame = +2 Query: 641 EQGLVKSVGVSNYSEKRLRDA--HDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDEL 814 ++GL +S+GVSNY + + DA + R+K A+ Q+ + + P+ + + Sbjct: 158 DKGLARSIGVSNYQAQSVYDALIYARIKP-----ATLQIEHHPYLQQPD---LVSLAQTE 209 Query: 815 GITLIAYSPIAQGALTGKYTPANPPTG------PRGRIYTSDFLSKLQPLINK--IRVIG 970 GI + AYS PTG PR + + PL++ I+ + Sbjct: 210 GIVVTAYSSFG-------------PTGFMELDMPRAK--------SVAPLMDSPVIKALA 248 Query: 971 GSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREV- 1147 + +TP QV+L W +G + IP E + + L +++ ++ M + Sbjct: 249 DKHRRTPAQVLLRWATQRG-IAVIPKTSRPEVMAQNLDNTSFDLDSEDLAKIADMDLNIR 307 Query: 1148 --KPVMGFPVEKL*ICG 1192 KP F KL + G Sbjct: 308 FNKPTNYFSANKLYLFG 324
>Q9P430:XYL1_CANSH NAD(P)H-dependent D-xylose reductase - Candida shehatae (Yeast)| Length = 323 Score = 39.7 bits (91), Expect = 0.030 Identities = 74/341 (21%), Positives = 132/341 (38%), Gaps = 34/341 (9%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVS 394 +G+ + +G G W +T A ++A + +G FD AE YG Sbjct: 13 NGLEMPSIGFGCWKLDKSTA-------------ADQVYNA-IKAGYRLFDGAEDYG---- 54 Query: 395 GAINSESLLGRFIKERQEKEKVDVAIATK----FAALPWR--FGRGSVISALKGSLSRLG 556 +E +G +K +D I T+ + W +V +AL +L L Sbjct: 55 ----NEQEVGEGVKRA-----IDEGIVTREEIFLTSKLWNNYHDPKNVETALNKTLKDLK 105 Query: 557 VSSVESYQLHWP--------------GIWGNEG----YLD--------GLADAYEQGLVK 658 V V+ + +H+P G + +G Y D L + G ++ Sbjct: 106 VDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFVYEDVPILETWKALEKLVKAGKIR 165 Query: 659 SVGVSNYSEKRLRDAHDRLKKRGVPL--ASNQVNYSLIYRNPEENGVKAACDELGITLIA 832 S+GVSN+ L D RG + A QV + + P+ + ++GIT+ A Sbjct: 166 SIGVSNFPGALLLDLF-----RGATIKPAVLQVEHHPYLQQPK---LIEYAQKVGITVTA 217 Query: 833 YSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPTQVVLNW 1012 YS + P + +GR + L + + I+ I ++K P +V+L W Sbjct: 218 YS---------SFGPQSFVEMNQGRALNTPTLFEH----DVIKAIAAKHNKVPAEVLLRW 264 Query: 1013 LICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 Q + IP + E+ + + LT+++ EE+ + Sbjct: 265 -SAQRGIAVIPKSNLPERLVQNRSFNDFELTKEDFEEISKL 304
>P97382:KCAB3_MOUSE Voltage-gated potassium channel subunit beta-3 - Mus musculus (Mouse)| Length = 249 Score = 39.3 bits (90), Expect = 0.039 Identities = 53/226 (23%), Positives = 91/226 (40%), Gaps = 24/226 (10%) Frame = +2 Query: 530 LKGSLSRLGVSSVESYQLHWPGIWGN--------EGYLDGLADAYEQGLVKSVGVSNYSE 685 L+GSL RL + V+ ++ N E + + QGL G S +S Sbjct: 26 LQGSLDRLQLEYVDI-------VFANRSDPNSPMEEIVRAMTYVINQGLALYWGTSRWSA 78 Query: 686 KRLRDAHDRLKKRG-VPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQGALT 862 + +A+ ++ +P Q R E + ++G+ + +SP+A G +T Sbjct: 79 AEIMEAYSMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACGLIT 138 Query: 863 GKYTPANPPT---GPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTPT---------QVVL 1006 KY P T +G + + + + + RV+ D PT Q+ + Sbjct: 139 SKYDGRVPDTCKATVKGYQWLKEKVQSEEGKKQQARVM----DLLPTARQLGCTVGQLAI 194 Query: 1007 NW-LICQGNVVPIPGAKNAEQAREFAGALGWL--LTEQEVEELRSM 1135 W L +G + G +AEQ E G+L L LT Q V E+ ++ Sbjct: 195 AWCLRSEGVSSVLLGVSSAEQLMEHLGSLQVLSQLTPQTVVEIDAL 240
>P14550:AK1A1_HUMAN Alcohol dehydrogenase [NADP+] - Homo sapiens (Human)| Length = 325 Score = 38.9 bits (89), Expect = 0.050 Identities = 60/295 (20%), Positives = 117/295 (39%), Gaps = 22/295 (7%) Frame = +2 Query: 317 KGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALP 496 K A ++ G D A +YG +E +G +KE K + Sbjct: 30 KAAVKYALSVGYRHIDCAAIYG--------NEPEIGEALKEDVGPGKAVPREELFVTSKL 81 Query: 497 W--RFGRGSVISALKGSLSRLGVSSVESYQLHWPGIW--GNEGY---LDG---------- 625 W + V AL+ +L+ L + ++ Y +HWP + G+ + DG Sbjct: 82 WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYK 141 Query: 626 -----LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENG 790 L +GLV+++G+SN++ +++ D L V A QV + +N Sbjct: 142 ETWKALEALVAKGLVQALGLSNFNSRQIDDI---LSVASVRPAVLQVE---CHPYLAQNE 195 Query: 791 VKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIG 970 + A C G+ + AYSP+ + P P + +P+ + + Sbjct: 196 LIAHCQARGLEVTAYSPLGSSDRAWR-DPDEP-------------VLLEEPV---VLALA 238 Query: 971 GSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 Y ++P Q++L W + Q V+ IP + + + + + +E+++L ++ Sbjct: 239 EKYGRSPAQILLRWQV-QRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNAL 292
>P38715:GRE3_YEAST NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae| (Baker's yeast) Length = 327 Score = 38.5 bits (88), Expect = 0.066 Identities = 72/348 (20%), Positives = 128/348 (36%), Gaps = 36/348 (10%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVS 394 +G+ + +G+G W N +K FD + D G + G G+ Sbjct: 9 NGLKMPLVGLGCWKIDKKVCANQIY---EAIKLGYRLFDGACDYG-----NEKEVGEGIR 60 Query: 395 GAINSESLLGRFIKERQEKEKVDVAIATKFAALPWR--FGRGSVISALKGSLSRLGVSSV 568 AI SE L+ R D+ + +K W V ALK +LS +G+ + Sbjct: 61 KAI-SEGLVSR----------KDIFVVSKL----WNNFHHPDHVKLALKKTLSDMGLDYL 105 Query: 569 ESYQLHWPGIWG----NEGYLDG--------------------------LADAYEQGLVK 658 + Y +H+P + E Y G L + ++GL+K Sbjct: 106 DLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIK 165 Query: 659 SVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYS 838 S+GVSN+ ++D + + V L Y + + C I ++AYS Sbjct: 166 SIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYL------TQEHLVEFCKLHDIQVVAYS 219 Query: 839 PIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLI---NKIRVIGGSY-DKTPTQVVL 1006 GP+ I L+K P + + I+ + ++ T +QV+L Sbjct: 220 SF----------------GPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLL 263 Query: 1007 NWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 W +G V +K + LTEQE++++ ++ ++ Sbjct: 264 RWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISALNANIR 311
>P52895:AK1C2_HUMAN Aldo-keto reductase family 1 member C2 - Homo sapiens (Human)| Length = 323 Score = 38.5 bits (88), Expect = 0.066 Identities = 60/299 (20%), Positives = 117/299 (39%), Gaps = 23/299 (7%) Frame = +2 Query: 323 AFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAAL 493 A ++++G D+A VY N+E +G I+ + V D+ +K + Sbjct: 37 AVKLAIEAGFHHIDSAHVY--------NNEEQVGLAIRSKIADGSVKREDIFYTSKLWSN 88 Query: 494 PWRFGRGSVISALKGSLSRLGVSSVESYQLHWP-GIWGNEGYL----------------- 619 R V AL+ SL L + V+ Y +H+P + E + Sbjct: 89 SHR--PELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCA 146 Query: 620 --DGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGV 793 + + + GL KS+GVSN++ + L ++ + P+ NQV + + + Sbjct: 147 TWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVC-NQVECHPYF---NQRKL 202 Query: 794 KAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGG 973 C I L+AYS + P P + D + + + Sbjct: 203 LDFCKSKDIVLVAYSALGSHR-------EEPWVDPNSPVLLEDPV---------LCALAK 246 Query: 974 SYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 + +TP + L + + +G VV + + N ++ R+ + LT +E++ + + R V+ Sbjct: 247 KHKRTPALIALRYQLQRG-VVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVR 304
>Q3ZCJ2:AK1A1_BOVIN Alcohol dehydrogenase [NADP+] - Bos taurus (Bovine)| Length = 325 Score = 38.5 bits (88), Expect = 0.066 Identities = 59/300 (19%), Positives = 120/300 (40%), Gaps = 22/300 (7%) Frame = +2 Query: 317 KGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALP 496 K A ++ G D A +YG +E+ +G +KE K+ + Sbjct: 30 KAAIKYALSVGYRHIDCAAIYG--------NETEIGEALKENVGPGKLVPREELFVTSKL 81 Query: 497 W--RFGRGSVISALKGSLSRLGVSSVESYQLHWPGIW--GNEGY---LDG---------- 625 W + V AL+ +L+ L + ++ Y +HWP + G+ + DG Sbjct: 82 WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDSPFPKNADGTIRYDSTHYK 141 Query: 626 -----LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENG 790 L +GLV+++G+SN++ +++ D L V A QV + +N Sbjct: 142 ETWRALEALVAKGLVRALGLSNFNSRQIDDV---LSVASVRPAVLQVE---CHPYLAQNE 195 Query: 791 VKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIG 970 + A C + + AYSP+ + P P + +P+ + + Sbjct: 196 LIAHCQARNLEVTAYSPLGSSDRAWR-DPEEP-------------VLLKEPV---VLALA 238 Query: 971 GSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 + ++P Q++L W + Q V IP + + E + + +E+++L ++ + ++ Sbjct: 239 EKHGRSPAQILLRWQV-QRKVSCIPKSVTPSRILENIQVFDFTFSPEEMKQLDALNKNLR 297
>P51652:AKC1H_RAT Aldo-keto reductase family 1 member C18 - Rattus norvegicus (Rat)| Length = 323 Score = 38.1 bits (87), Expect = 0.086 Identities = 74/297 (24%), Positives = 125/297 (42%), Gaps = 25/297 (8%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAALPWRF 505 ++D G D + +Y +E +G+ I + E V D+ +K + R Sbjct: 41 AIDVGFRHIDCSHLY--------QNEEEIGQAIVSKIEDGTVKREDIFYTSKLWSTSHR- 91 Query: 506 GRGSVISALKGSLSRLGVSSVESYQLHWPGIW--GNEGY---------LD--GLADAYEQ 646 V +L+ SL +L + V+ Y +H+P G+E LD L D +E Sbjct: 92 -PELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGDELLPQDEHGNLILDTVDLCDTWEA 150 Query: 647 -------GLVKSVGVSNYSEKRLRDAHDR--LKKRGVPLASNQVNYSLIYRNPEENGVKA 799 GL KS+GVSN++ ++L ++ LK R V NQV L Y N ++ + A Sbjct: 151 MEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPV---CNQVECHL-YLN--QSKLLA 204 Query: 800 ACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSY 979 C I L+AY A G KY N T + D + + + Y Sbjct: 205 YCKMNDIVLVAYG--ALGTQRYKYC-INEDT----PVLLDDPI---------LCTMAKKY 248 Query: 980 DKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 +TP + L + + +G +V + + N E+ RE + L ++E L ++ R ++ Sbjct: 249 KRTPALIALRYQLERG-IVTLVKSFNEERIRENLQVFDFQLASDDMEILDNLDRNLR 304
>Q8K023:AKC1H_MOUSE Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse)| Length = 323 Score = 37.7 bits (86), Expect = 0.11 Identities = 70/298 (23%), Positives = 124/298 (41%), Gaps = 26/298 (8%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAALPWRF 505 ++D G D + +Y +E +G+ I + E V D+ +K + R Sbjct: 41 AIDVGFCHIDCSHLY--------QNEEEIGQAILSKIEDGTVKREDIFYTSKLWSTSHR- 91 Query: 506 GRGSVISALKGSLSRLGVSSVESYQLHWPGIW--GNE-------GYLD----GLADAYEQ 646 V +L+ SL +L + V+ Y +H+P GNE G L L D +E Sbjct: 92 -PELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEA 150 Query: 647 -------GLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAAC 805 GL KS+GVSN++ ++L ++ + P+ NQV L Y N ++ + A C Sbjct: 151 MEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVC-NQVECHL-YLN--QSKLLAYC 206 Query: 806 DELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVI---GGS 976 I L+AY A G KY +++ P++ V+ Sbjct: 207 KMNDIVLVAYG--ALGTQRYKYC-----------------INEDTPVLLDDPVLCAMAKK 247 Query: 977 YDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 Y +TP + L + + +G +V + + N E+ RE + L +++ L + R ++ Sbjct: 248 YKRTPALIALRYQLDRG-IVALAKSFNEERIRENMQVFDFQLASDDMKILDGLDRNLR 304
>Q04828:AK1C1_HUMAN Aldo-keto reductase family 1 member C1 - Homo sapiens (Human)| Length = 323 Score = 37.7 bits (86), Expect = 0.11 Identities = 58/295 (19%), Positives = 116/295 (39%), Gaps = 23/295 (7%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAALPWRF 505 ++++G D+A +Y N+E +G I+ + V D+ +K R Sbjct: 41 AIEAGFRHIDSAHLY--------NNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHR- 91 Query: 506 GRGSVISALKGSLSRLGVSSVESYQLHWP-GIWGNEGYL-------------------DG 625 V AL+ SL L + V+ Y +H+P + E + + Sbjct: 92 -PELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEA 150 Query: 626 LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAAC 805 + + GL KS+GVSN++ ++L ++ + P+ NQV + + + C Sbjct: 151 VEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVC-NQVECHPYF---NQRKLLDFC 206 Query: 806 DELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDK 985 I L+AYS + P P + D + + + + + Sbjct: 207 KSKDIVLVAYSALGSHR-------EEPWVDPNSPVLLEDPV---------LCALAKKHKR 250 Query: 986 TPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 TP + L + + +G VV + + N ++ R+ + LT +E++ + + R V+ Sbjct: 251 TPALIALRYQLQRG-VVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVR 304
>O70473:AK1A1_CRIGR Alcohol dehydrogenase [NADP+] - Cricetulus griseus (Chinese| hamster) Length = 228 Score = 37.0 bits (84), Expect = 0.19 Identities = 46/198 (23%), Positives = 82/198 (41%), Gaps = 22/198 (11%) Frame = +2 Query: 317 KGAFDASVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALP 496 K A ++ G D A VYG +E +G +KE K + Sbjct: 15 KAAIKYALSVGYRHIDCAAVYG--------NEIEIGEALKENVGPGKAVPREELFVTSKL 66 Query: 497 W--RFGRGSVISALKGSLSRLGVSSVESYQLHWPGIW---------GNEGYLDGLADAYE 643 W + V +AL+ +L+ L + ++ Y +HWP + ++G + + Y+ Sbjct: 67 WNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNDDGTIRYDSTHYK 126 Query: 644 Q-----------GLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENG 790 + GLVK++G+SN++ +++ D L V A QV + +N Sbjct: 127 ETWKALEALVAKGLVKALGLSNFNSRQIDDI---LSVASVRPAVLQVE---CHPYLAQNE 180 Query: 791 VKAACDELGITLIAYSPI 844 + A C G+ + AYSP+ Sbjct: 181 LIAHCQARGLEVTAYSPL 198
>Q9H987:SYP2L_HUMAN Synaptopodin 2-like protein - Homo sapiens (Human)| Length = 977 Score = 36.2 bits (82), Expect = 0.33 Identities = 46/172 (26%), Positives = 62/172 (36%), Gaps = 11/172 (6%) Frame = -3 Query: 537 PFSAEITLPRPNLHGRAANFVAMATSTFSFSCLSLINLPSRLSEFIAPDTPA-----PYT 373 P A + PRP G A A PS + P TP P T Sbjct: 439 PLPAPVASPRPFQPGGGAPTPA----------------PSIFNRSARPFTPGLQGQRPTT 482 Query: 372 SAVSKKVIPLSTLASNAPLASLS-----FLSSHWKSFQ*VVSPQDQAPMPSLVTATPDAP 208 ++V + PL+ +N L LS FLSS Q P+PS + P Sbjct: 483 TSVIFR--PLAPKRANDSLGGLSPAPPPFLSS-----------QGPTPLPSFTSGVPSHA 529 Query: 207 SIALLPSSTAAPSDVTARGGRN-PAVRRWPRSGRQPQHPAPPATCRAIADGS 55 ++ PS+ + VTA PA R G P+ PAPP+ + S Sbjct: 530 PVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTAS 581
>P56958:RNB_HHV1M RNA-binding protein - Human herpesvirus 1 (strain MP) (HHV-1)| (Human herpes simplex virus 1) Length = 161 Score = 35.8 bits (81), Expect = 0.43 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Frame = -3 Query: 267 VSPQDQAPMPSLVTATPDAPSIALLPSSTAAPSDVTA-RGGRNPAVRRWPRSGRQPQHPA 91 +S +A P + TP P +P P + R R+P V R PR RQP+ P Sbjct: 72 ISKPSEAVRPPTIPRTPRVPREPRVPRPPREPREPRVPRASRDPRVPRDPRDPRQPRSPR 131 Query: 90 PPATCR 73 P + R Sbjct: 132 EPRSPR 137
>Q9P7E8:APP1_SCHPO Protein app1 - Schizosaccharomyces pombe (Fission yeast)| Length = 857 Score = 35.8 bits (81), Expect = 0.43 Identities = 40/149 (26%), Positives = 66/149 (44%), Gaps = 1/149 (0%) Frame = -3 Query: 507 PNLHGRAANFVAMATSTFSFSCLSLINLPSRLSEFIAPDTPAPYTSAVSKKVIPLSTLAS 328 P + ++F + A ++F+ N P+ +S AP+ P TS S + P + Sbjct: 438 PKTAAKISSFNSKAGTSFA-KPRPFTNNPNPIS---APEKP---TSGESLSLNPPPAMPK 490 Query: 327 NAPLASLSFLSSHWKSFQ*-VVSPQDQAPMPSLVTATPDAPSIALLPSSTAAPSDVTARG 151 P +S S+ K+ Q V++P P P P+APS+ P++ AP +A Sbjct: 491 VFPERDIS--SASQKAAQPSVITPS--VPQPPAAPVVPEAPSVHQPPAAPVAPEVPSA-- 544 Query: 150 GRNPAVRRWPRSGRQPQHPAPPATCRAIA 64 + PA P + PQ PA P A++ Sbjct: 545 PQRPAAPVVPEAPSVPQRPAVPVVPEALS 573 Score = 33.1 bits (74), Expect = 2.8 Identities = 31/115 (26%), Positives = 47/115 (40%), Gaps = 2/115 (1%) Frame = -3 Query: 423 PSRLSEFIAPDTPA-PYTSAVSKKVIPLSTLASNAPLASLSFLSSHWKSFQ*VVSPQ-DQ 250 P R + + P+ P+ P AV V+P + P+A V+P+ Sbjct: 545 PQRPAAPVVPEAPSVPQRPAVP--VVPEALSVPQPPVAP--------------VAPEVPS 588 Query: 249 APMPSLVTATPDAPSIALLPSSTAAPSDVTARGGRNPAVRRWPRSGRQPQHPAPP 85 P P + P+APS+ P + AP + + PAV P + PQ PA P Sbjct: 589 VPQPPVAPVVPEAPSVPQPPVAPVAPEVPSV--PQRPAVPVVPEAPSVPQPPAAP 641
>Q80UE6:WNK4_MOUSE Serine/threonine-protein kinase WNK4 - Mus musculus (Mouse)| Length = 1222 Score = 35.4 bits (80), Expect = 0.56 Identities = 30/70 (42%), Positives = 35/70 (50%) Frame = -3 Query: 381 PYTSAVSKKVIPLSTLASNAPLASLSFLSSHWKSFQ*VVSPQDQAPMPSLVTATPDAPSI 202 PY A S ++PLS+ AS PL S S S F PQD P T+ P PS Sbjct: 841 PYPQAPSS-LLPLSSSASQVPLPSSSLPISAPLPFS-PSYPQD----PLSPTSLPVCPSP 894 Query: 201 ALLPSSTAAP 172 LPS+TAAP Sbjct: 895 PSLPSTTAAP 904
>P05980:PGFS1_BOVIN Prostaglandin-F synthase 1 - Bos taurus (Bovine)| Length = 323 Score = 35.4 bits (80), Expect = 0.56 Identities = 37/177 (20%), Positives = 77/177 (43%) Frame = +2 Query: 620 DGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKA 799 + L + GL KS+GVSN++ K+L ++ + P+ NQV + ++ + Sbjct: 149 EALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVC-NQVE---CHPYLNQSKLLE 204 Query: 800 ACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSY 979 C I L+AY+ + L+ NP + D + + I + Sbjct: 205 FCKSHDIVLVAYAALGAQLLSEWVNSNNP-------VLLEDPV---------LCAIAKKH 248 Query: 980 DKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 +TP V L + + +G VV + + N ++ +E + LT ++++ + + R ++ Sbjct: 249 KQTPALVALRYQVQRG-VVVLAKSFNKKRIKENMQVFDFELTPEDMKAIDGLNRNIR 304
>P52898:DDBX_BOVIN Dihydrodiol dehydrogenase 3 - Bos taurus (Bovine)| Length = 323 Score = 35.4 bits (80), Expect = 0.56 Identities = 61/287 (21%), Positives = 116/287 (40%), Gaps = 23/287 (8%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAALPWRF 505 ++++G D+A +Y +E +G+ I+ + V D+ +K + R Sbjct: 41 AIEAGFRHIDSAHLY--------QNEEQVGQAIRSKIADGTVKREDIFYTSKLWSTSLR- 91 Query: 506 GRGSVISALKGSLSRLGVSSVESYQLHWPGIWGNEGYL--------------------DG 625 V AL+ SL+ L + V+ Y +H+P L + Sbjct: 92 -PELVRPALEKSLNNLQLDYVDLYIIHFPVALKPGETLFPTDENGKPIFDSVDLCRTWEA 150 Query: 626 LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAAC 805 L + GL KS+GVSN++ K+L ++ + P+ NQV + ++ + C Sbjct: 151 LEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVC-NQVECHPYF---NQSKLLDFC 206 Query: 806 DELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDK 985 I L+AY + L P P FL + P+++ I + + Sbjct: 207 KSHDIVLVAYGALGSQRLKEWVNPNLP------------FLLE-DPVLS---AIAKKHRQ 250 Query: 986 TPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEEL 1126 TP V L + I +G VV + + N ++ +E + LT ++++ + Sbjct: 251 TPALVALRYQIQRG-VVVLAKSYNKKRIKENIQVFDFELTPEDMKAI 296
>P31867:XYL1_PICST NAD(P)H-dependent D-xylose reductase - Pichia stipitis (Yeast)| Length = 318 Score = 35.0 bits (79), Expect = 0.73 Identities = 64/298 (21%), Positives = 114/298 (38%), Gaps = 31/298 (10%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEK---EKVDVAIATKFAALPWR- 502 ++ +G FD AE Y +E L+G +K+ ++ ++ D+ + +K W Sbjct: 34 AIKTGYRLFDGAEDYA--------NEKLVGAGVKKAIDEGIVKREDLFLTSKL----WNN 81 Query: 503 -FGRGSVISALKGSLSRLGVSSVESYQLHWP------------------GIWGNEGYLD- 622 +V AL +LS L V V+ + +H+P G N Y D Sbjct: 82 YHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLEEKYPPGFYCGKGDNFDYEDV 141 Query: 623 -------GLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPE 781 L + G ++S+GVSN+ L D L+ + + QV + + P Sbjct: 142 PILETWKALEKLVKAGKIRSIGVSNFPGALLLDL---LRGATIKPSVLQVEHHPYLQQPR 198 Query: 782 ENGVKAACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIR 961 + GI + AYS + P + +GR + L + + I+ Sbjct: 199 ---LIEFAQSRGIAVTAYS---------SFGPQSFVELNQGRALNTSPLFENET----IK 242 Query: 962 VIGGSYDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 I + K+P QV+L W Q + IP + + E + L EQ+ ++ + Sbjct: 243 AIAAKHGKSPAQVLLRW-SSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKL 299
>Q6Y0Z3:XYL1_CANPA NADH-dependent D-xylose reductase - Candida parapsilosis (Yeast)| Length = 324 Score = 35.0 bits (79), Expect = 0.73 Identities = 69/339 (20%), Positives = 130/339 (38%), Gaps = 32/339 (9%) Frame = +2 Query: 215 SGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGVS 394 SG + +G G W ND D ++ SG FD AE Y Sbjct: 14 SGYEIPLVGFGCWK-----LTNDVASDQ---------IYRAIKSGYRLFDGAEDYA---- 55 Query: 395 GAINSESLLGRFIKERQEKEKVDVAIATKFAALPWR--FGRGSVISALKGSLSRLGVSSV 568 +E +G IK R KE + + W + +V AL +LS L + V Sbjct: 56 ----NEQEVGEGIK-RAIKEGIVKREELFITSKLWNSFHDKKNVEVALMKTLSDLNLDYV 110 Query: 569 ESYQLHWP--------------GIWGNEG---------YLD---GLADAYEQGLVKSVGV 670 + + +H+P G + +G LD L +QGL KS+G+ Sbjct: 111 DLFYIHFPIAQKPVPIEKKYPPGFYCGDGDKWSIEEVPLLDTWRALEKLVDQGLAKSIGI 170 Query: 671 SNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGITLIAYSPIAQ 850 SN+S + + +D ++ + + Q+ + P+ L+ Y + Sbjct: 171 SNFSAQLI---YDLIRGCTIKPVALQIEHHPYLTQPK--------------LVEYVQLHD 213 Query: 851 GALTGKYTPANPPTGPRGRIYTSDFLSKLQ-PLINK---IRVIGGSYDKTPTQVVLNWLI 1018 +TG Y+ P + D L P++ + ++ I + K+P QV+L + Sbjct: 214 IQITG-YSSFGPQS-----FLEMDLKRALDTPVLLEEPTVKSIADKHGKSPAQVLLRYQT 267 Query: 1019 CQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSM 1135 +G + IP + + ++ + + + LT+ +++ + + Sbjct: 268 QRG-IAVIPRSNSPDRMAQNLSVIDFELTQDDLQAIAEL 305
>P04487:RNB_HHV11 RNA-binding protein - Human herpesvirus 1 (strain 17) (HHV-1)| (Human herpes simplex virus 1) Length = 161 Score = 35.0 bits (79), Expect = 0.73 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Frame = -3 Query: 267 VSPQDQAPMPSLVTATPDAPSIALLPSSTAAPSDVTA-RGGRNPAVRRWPRSGRQPQHPA 91 +S +A P + TP P +P P + R R+P V R PR RQP+ P Sbjct: 72 ISKPSEAVRPPTIPRTPRVPREPRVPRPPREPREPRVPRAPRDPRVPRDPRDPRQPRSPR 131 Query: 90 PPATCR 73 P + R Sbjct: 132 EPRSPR 137
>O94735:XYL1_PICGU NADPH-dependent D-xylose reductase - Pichia guilliermondii (Yeast)| (Candida guilliermondii) Length = 317 Score = 34.7 bits (78), Expect = 0.95 Identities = 36/172 (20%), Positives = 74/172 (43%), Gaps = 2/172 (1%) Frame = +2 Query: 641 EQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGI 820 E+G ++S+G+SN+ ++D L+ + A Q+ + + P + GI Sbjct: 154 EKGKIRSIGISNFPGALIQDL---LRGAKIKPAVLQIEHHPYLQQPR---LIEYVQSQGI 207 Query: 821 TLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINK--IRVIGGSYDKTPT 994 + AYS + + N P + ++PL I+ + +KTP Sbjct: 208 AITAYSSFGPQS----FVELNHPR-----------VKDVKPLFEHDVIKSVAEKANKTPA 252 Query: 995 QVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 QV+L W +G V IP + N ++ + L++++ +E+ + E++ Sbjct: 253 QVLLRWATQRGLAV-IPKSNNPDRLLSNLKVNDFDLSQEDFKEISKLDIELR 303
>P49378:XYL1_KLULA NAD(P)H-dependent D-xylose reductase - Kluyveromyces lactis (Yeast)| (Candida sphaerica) Length = 329 Score = 34.3 bits (77), Expect = 1.2 Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 4/174 (2%) Frame = +2 Query: 641 EQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDELGI 820 +QG +KS+G+SN+S ++D + + V L Y +E +K GI Sbjct: 163 DQGKIKSLGISNFSGALIQDLLRGARIKPVALQIEHHPYL-----TQERLIKYV-KNAGI 216 Query: 821 TLIAYS---PIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTP 991 ++AYS P++ L K N PT ++ D I+ I + TP Sbjct: 217 QVVAYSSFGPVSFLELENK-KALNTPT-----LFEHD----------TIKSIASKHKVTP 260 Query: 992 TQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWL-LTEQEVEELRSMAREVK 1150 QV+L W Q + IP + E+ + L LT+ E++++ + + ++ Sbjct: 261 QQVLLRW-ATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISGLNQNIR 313
>P24939:V33P_ADE02 33 kDa phosphoprotein - Human adenovirus 2 (HAdV-2)| Length = 228 Score = 34.3 bits (77), Expect = 1.2 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Frame = -3 Query: 255 DQAPMPSLVTATPDAPSIALLPS--STAAPSDVTARGGRNPAVRRWPRSGRQPQHPAPPA 82 D+ P PS+ +P +A +PS +T+AP A R P RRW +G + AP A Sbjct: 53 DETPSPSVAFPSPAPQKLATVPSIATTSAPQAPPALPVRRPN-RRWDTTGTRAAPTAPAA 111 Query: 81 TCRA 70 A Sbjct: 112 AAAA 115
>P50555:TNR1A_PIG Tumor necrosis factor receptor superfamily member 1A precursor -| Sus scrofa (Pig) Length = 461 Score = 34.3 bits (77), Expect = 1.2 Identities = 25/95 (26%), Positives = 41/95 (43%) Frame = -3 Query: 342 STLASNAPLASLSFLSSHWKSFQ*VVSPQDQAPMPSLVTATPDAPSIALLPSSTAAPSDV 163 S + S +P++S +F W + + P++ AP P P + + P+ST P+ + Sbjct: 286 SPVPSFSPISSPTFTPCDWSNIKVTSPPKEIAPPPQ-----GAGPILPMPPASTPVPTPL 340 Query: 162 TARGGRNPAVRRWPRSGRQPQHPAPPATCRAIADG 58 GG + P A PAT A+ DG Sbjct: 341 PKWGGSAHSAHSAPAQ----LADADPATLYAVVDG 371
>Q8BWB1:SYP2L_MOUSE Synaptopodin 2-like protein - Mus musculus (Mouse)| Length = 975 Score = 34.3 bits (77), Expect = 1.2 Identities = 48/177 (27%), Positives = 67/177 (37%), Gaps = 5/177 (2%) Frame = -3 Query: 570 STEETPRRESEPFSAEITLPRPNLHGRAANFVAMATSTFSFSCLSLINLPSRLSEFIAPD 391 S + PR +S P A + LP L + A++ + F + I PS + P Sbjct: 415 SLQSPPRAQSAPPEAAV-LPLSPL-----SVPAVSPTPFFPDGGAPIPAPSIFNRSARPF 468 Query: 390 TPA---PYTSAVSKKVIPLSTLASNAPLASLSFLSSHWKSFQ*VVSPQDQAPMPSLVTAT 220 TP + S PL+ N L S S S + + PQ P+PS T Sbjct: 469 TPGLQGQRSGTTSVIFRPLAPKKVNEGLGSTSPAPSPFAA-----PPQGPTPLPSFTTVV 523 Query: 219 PDAPSIALLPSSTAAPS-DVTARGGRN-PAVRRWPRSGRQPQHPAPPATCRAIADGS 55 P ++ SST S VTA PA R G P+ P PP+ + S Sbjct: 524 PSHTPVSGASSSTQRSSGPVTATSSLYIPAPSRPVTPGGAPEPPTPPSAAAMTSTAS 580
>P54728:RD23B_MOUSE UV excision repair protein RAD23 homolog B - Mus musculus (Mouse)| Length = 416 Score = 34.3 bits (77), Expect = 1.2 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 3/79 (3%) Frame = -3 Query: 264 SPQDQAPMPSLVTATPDAPSIALLPSSTAA---PSDVTARGGRNPAVRRWPRSGRQPQHP 94 SP + P++ A AP+ AL P+ST A P+ TA PA P + Sbjct: 95 SPTTVSSSPAVAAAQAPAPTPALAPTSTPASTTPASTTASSEPAPAGATQPEKPAEKPAQ 154 Query: 93 APPATCRAIADGSGGRNYR 37 P T A AD + G + R Sbjct: 155 TPVLTSPAPADSTPGDSSR 173
>P52897:PGFS2_BOVIN Prostaglandin-F synthase 2 - Bos taurus (Bovine)| Length = 323 Score = 34.3 bits (77), Expect = 1.2 Identities = 37/177 (20%), Positives = 76/177 (42%) Frame = +2 Query: 620 DGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKA 799 + L + GL KS+GVSN++ K+L ++ + P+ NQV + ++ + Sbjct: 149 EALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVC-NQVE---CHPYLNQSKLLE 204 Query: 800 ACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSY 979 C I L+AY+ + L+ NP + D + + I + Sbjct: 205 FCKSHDIVLVAYAALGAQLLSEWVNSNNP-------VLLEDPV---------LCAIAKKH 248 Query: 980 DKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 +TP V L + + +G VV + + N ++ +E + LT ++++ + + R + Sbjct: 249 KQTPALVALRYQVQRG-VVVLAKSFNKKRIKENMQVFDFELTPEDMKAIDGLNRNTR 304
>Q8TAX7:MUC7_HUMAN Mucin-7 precursor - Homo sapiens (Human)| Length = 377 Score = 34.3 bits (77), Expect = 1.2 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 1/66 (1%) Frame = -3 Query: 264 SPQDQAPMPSLVTAT-PDAPSIALLPSSTAAPSDVTARGGRNPAVRRWPRSGRQPQHPAP 88 +PQD P +AT P PS + P +TAAP +A P+ P + P P P Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAP--PTP 218 Query: 87 PATCRA 70 PAT A Sbjct: 219 PATTPA 224 Score = 32.3 bits (72), Expect = 4.7 Identities = 36/121 (29%), Positives = 42/121 (34%), Gaps = 11/121 (9%) Frame = -3 Query: 399 APDTPAPYTSAVSKKVIPLSTLAS------NAPLASLSFLSSHWKSFQ*VVSPQDQAPM- 241 AP TP+ T A P T A+ P S + S AP+ Sbjct: 191 APPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLS 250 Query: 240 ---PSLVTATPDAPSIALL-PSSTAAPSDVTARGGRNPAVRRWPRSGRQPQHPAPPATCR 73 P TA P PS L PSS +AP + TA A P P PAP T Sbjct: 251 SSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAP-----PSSPAPQETTA 305 Query: 72 A 70 A Sbjct: 306 A 306
>Q2QLG9:CTTB2_OTOGA Cortactin-binding protein 2 - Otolemur garnettii (Small-eared| galago) (Garnett's greater bushbaby) Length = 1655 Score = 34.3 bits (77), Expect = 1.2 Identities = 20/58 (34%), Positives = 23/58 (39%) Frame = -3 Query: 258 QDQAPMPSLVTATPDAPSIALLPSSTAAPSDVTARGGRNPAVRRWPRSGRQPQHPAPP 85 ++ P P +TPDAP A P S A P G P P S P APP Sbjct: 374 EENGPSPG---STPDAPGSAAPPGSAAPPGSAAPPGSAAPPGSAAPHSFHSPCASAPP 428
>Q8R4X3:RBM12_MOUSE RNA-binding protein 12 - Mus musculus (Mouse)| Length = 1002 Score = 33.9 bits (76), Expect = 1.6 Identities = 40/181 (22%), Positives = 61/181 (33%), Gaps = 17/181 (9%) Frame = -3 Query: 543 SEPFSAEITLPR--PNLHGRAANFVAMATSTF-------SFSCLSLINLPSRLSEFIA-- 397 S S+ + LP PN + + + V TS +FS S+ P + Sbjct: 110 SSGMSSRVNLPAIVPNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPSMGTSFGSP 169 Query: 396 ------PDTPAPYTSAVSKKVIPLSTLASNAPLASLSFLSSHWKSFQ*VVSPQDQAPMPS 235 P T +P + + P+ + S PL S+ + P+P Sbjct: 170 TFSSTIPSTASPMNTVPPPPIPPIPAMPSLPPLPSIPPI-----------------PVPP 212 Query: 234 LVTATPDAPSIALLPSSTAAPSDVTARGGRNPAVRRWPRSGRQPQHPAPPATCRAIADGS 55 V P P + +P + P P P SG P +P P A A +GS Sbjct: 213 PVPTLPPVPPVPPIPPVPSVP----------PMTTLPPMSGMPPLNPPPVAPLPAGMNGS 262 Query: 54 G 52 G Sbjct: 263 G 263
>Q5REQ0:AK1C1_PONPY Aldo-keto reductase family 1 member C1 homolog - Pongo pygmaeus| (Orangutan) Length = 323 Score = 33.9 bits (76), Expect = 1.6 Identities = 56/295 (18%), Positives = 116/295 (39%), Gaps = 23/295 (7%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKV---DVAIATKFAALPWRF 505 ++++G D+A +Y N+E +G I+ + V D+ +K R Sbjct: 41 AIEAGFRHIDSAHLY--------NNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHR- 91 Query: 506 GRGSVISALKGSLSRLGVSSVESYQLHWP-GIWGNEGYL-------------------DG 625 V AL+ SL L + V+ Y +H+P + E + + Sbjct: 92 -PELVRPALERSLKNLQLDYVDLYLVHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEA 150 Query: 626 LADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAAC 805 + + GL KS+GVSN++ ++L ++ + P+ NQV + + + C Sbjct: 151 MEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVC-NQVECHPYF---NQRKLLDFC 206 Query: 806 DELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDK 985 I L+AYS + K+ N P + + + + + Sbjct: 207 KSKDIVLVAYSALGSHR-EEKWVDPNSPVLLEDPV---------------LCALAKKHKQ 250 Query: 986 TPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 TP + L + + +G VV + + N ++ R+ + LT ++++ + + R ++ Sbjct: 251 TPALIALRYQLQRG-VVVLAKSYNEQRIRQNMQVFDFQLTSEDMKTIDGLNRNMR 304
>Q9P1Z0:ZBTB4_HUMAN Zinc finger and BTB domain-containing protein 4 - Homo sapiens| (Human) Length = 1013 Score = 33.5 bits (75), Expect = 2.1 Identities = 25/81 (30%), Positives = 36/81 (44%) Frame = -3 Query: 258 QDQAPMPSLVTATPDAPSIALLPSSTAAPSDVTARGGRNPAVRRWPRSGRQPQHPAPPAT 79 ++ P P ATP +P+ A+ P++ A P+ T A R PR+GR + A P Sbjct: 520 REYPPPPPEPAATPTSPATAVSPATAAGPAMATT---TEEAKGRNPRAGRTLTYTAKP-- 574 Query: 78 CRAIADGSGGRNYRGVVSGRG 16 G GG +GRG Sbjct: 575 ----VGGIGGGGGPPTGAGRG 591
>P11847:RCEM_RHOCA Reaction center protein M chain - Rhodobacter capsulatus| (Rhodopseudomonas capsulata) Length = 307 Score = 33.5 bits (75), Expect = 2.1 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 15/103 (14%) Frame = +2 Query: 251 WSWGDTTYWNDFQWDDRKLKDAKGAFDA-------SVDSGITFFDT------AEVYGAGV 391 W W +W + G F S+D G F++ A +YG+ + Sbjct: 154 WLWSVLGFWRPILMGSWSVAPPYGIFSHLDWTNQFSLDHGNLFYNPFHGLSIAALYGSAL 213 Query: 392 SGAINSESLLG--RFIKERQEKEKVDVAIATKFAALPWRFGRG 514 A++ ++L RF ER+ ++ VD A++ AAL WR+ G Sbjct: 214 LFAMHGATILAVTRFGGERELEQIVDRGTASERAALFWRWTMG 256
>Q82K53:IF2_STRAW Translation initiation factor IF-2 - Streptomyces avermitilis| Length = 1046 Score = 33.5 bits (75), Expect = 2.1 Identities = 24/78 (30%), Positives = 29/78 (37%) Frame = -3 Query: 249 APMPSLVTATPDAPSIALLPSSTAAPSDVTARGGRNPAVRRWPRSGRQPQHPAPPATCRA 70 AP P+ P AP PS+ AAP+ A PR G +P P P A Sbjct: 117 APRPAPAAPAPAAPEFTAPPSAPAAPA----------AAASGPRPGARPGAPKPGGARPA 166 Query: 69 IADGSGGRNYRGVVSGRG 16 G RG + RG Sbjct: 167 TPGQGQGGQVRGERTDRG 184
>Q924A2:CIC_MOUSE Protein capicua homolog - Mus musculus (Mouse)| Length = 2510 Score = 33.5 bits (75), Expect = 2.1 Identities = 35/102 (34%), Positives = 46/102 (45%), Gaps = 10/102 (9%) Frame = -3 Query: 423 PSRLSEFIAPDTPAPYTSAVSKKVIPLST------LASNAPLASLSFLSSHWKSFQ*VVS 262 P+ ++ AP PAP TS + +P T LA+ AP A + L S + Sbjct: 1749 PAPGTKAAAPSGPAPTTSI--RFTLPPGTSTNGKVLAATAPTAGIPILQSVPSA------ 1800 Query: 261 PQDQAPMPSLVTATPDAPSIALLPSST----AAPSDVTARGG 148 P +A S V ATP S LLP AAPS ++ RGG Sbjct: 1801 PPPKAQSVSPVQATPSGGSAQLLPGKVLVPLAAPS-MSVRGG 1841
>Q04893:YM96_YEAST Uncharacterized protein YMR317W - Saccharomyces cerevisiae (Baker's| yeast) Length = 1140 Score = 33.1 bits (74), Expect = 2.8 Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 13/150 (8%) Frame = -3 Query: 567 TEETPRRESEPFSAEITLPRPNLHGRAANFVAMATSTFSFSCLSLINLPSRLSEFIAPDT 388 + E P S S+E + + ++ +ATS+ S PS S ++ + Sbjct: 261 SSEAPSATSSSVSSEAS---SSTSSSVSSEAPLATSSVVSS-----EAPSSTSSVVSSEA 312 Query: 387 PAPYTSAVSKKVIPL--STLASNAPLASLSFLSSHWKSFQ*VV-----------SPQDQA 247 P+ +S+VS ++ S+++S APLA+ S +SS S S +A Sbjct: 313 PSSTSSSVSSEISSTTSSSVSSEAPLATSSVVSSEAPSSTSSSVSSEISSTTSSSVSSEA 372 Query: 246 PMPSLVTATPDAPSIALLPSSTAAPSDVTA 157 P+ + + +APS S+ APS ++ Sbjct: 373 PLATSSVVSSEAPSSTSSSVSSEAPSSTSS 402
>Q9JLU4:SHAN3_RAT SH3 and multiple ankyrin repeat domains protein 3 - Rattus norvegicus| (Rat) Length = 1815 Score = 33.1 bits (74), Expect = 2.8 Identities = 17/32 (53%), Positives = 21/32 (65%), Gaps = 2/32 (6%) Frame = -1 Query: 1073 PGPAPRSLPPGSAPR--CPGK*ASSEPPELGF 984 P P+PR+ PPGS P PG+ +S E PEL F Sbjct: 1326 PMPSPRAQPPGSIPADPGPGQGSSEEEPELVF 1357
>Q4ACU6:SHAN3_MOUSE SH3 and multiple ankyrin repeat domains protein 3 - Mus musculus| (Mouse) Length = 1805 Score = 33.1 bits (74), Expect = 2.8 Identities = 17/32 (53%), Positives = 21/32 (65%), Gaps = 2/32 (6%) Frame = -1 Query: 1073 PGPAPRSLPPGSAPR--CPGK*ASSEPPELGF 984 P P+PR+ PPGS P PG+ +S E PEL F Sbjct: 1325 PMPSPRAQPPGSIPADPGPGQGSSEEEPELVF 1356
>Q6R8J2:HEG_DANRE Protein HEG precursor - Danio rerio (Zebrafish) (Brachydanio rerio)| Length = 977 Score = 33.1 bits (74), Expect = 2.8 Identities = 29/108 (26%), Positives = 40/108 (37%), Gaps = 24/108 (22%) Frame = -3 Query: 396 PDTPAPYTSAVSKKVIPLSTLASNAPLASLSFLSSHWKSFQ*VV---------------- 265 P T VS +TL + P + L H+ + Q Sbjct: 435 PQVTDEATDEVSTVYSSTTTLTTTTPSVTTRQLQPHYTTVQTQTQHTTIVTTDIIQVLRT 494 Query: 264 SPQDQAPMPSLVTATPDAPSIA--------LLPSSTAAPSDVTARGGR 145 +P +P+L T+ P APS A L +STA P + TA GGR Sbjct: 495 TPSTAHHVPTLTTSGPQAPSTADSSDVTTLHLETSTATPGNTTAHGGR 542
>P21184:FLICA_PSEAE A-type flagellin - Pseudomonas aeruginosa| Length = 394 Score = 33.1 bits (74), Expect = 2.8 Identities = 26/88 (29%), Positives = 40/88 (45%) Frame = +2 Query: 212 ASGVAVTKLGIGAWSWGDTTYWNDFQWDDRKLKDAKGAFDASVDSGITFFDTAEVYGAGV 391 A+ V +GIGA+S GDT + + KD GA ++V SG+ DT G G Sbjct: 223 AAAVNDANVGIGAFSDGDT-----ISYVSKAGKDGSGAITSAV-SGVVIADTGST-GVGT 275 Query: 392 SGAINSESLLGRFIKERQEKEKVDVAIA 475 + + + F K K+D++ A Sbjct: 276 AAGVTPSAT--AFAKTNDTVAKIDISTA 301
>Q5R7C9:AK1C3_PONPY Aldo-keto reductase family 1 member C3 homolog - Pongo pygmaeus| (Orangutan) Length = 323 Score = 33.1 bits (74), Expect = 2.8 Identities = 57/292 (19%), Positives = 115/292 (39%), Gaps = 21/292 (7%) Frame = +2 Query: 335 SVDSGITFFDTAEVYGAGVSGAINSESLLGRFIKERQEKEKVDVAIATKFAALPWRFGRG 514 ++++G D+A +Y N+E +G I+ + V + L F R Sbjct: 41 AIEAGFRHIDSAHLY--------NNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRP 92 Query: 515 SVIS-ALKGSLSRLGVSSVESYQLHWP---------GIWGNEGYL-----------DGLA 631 ++ AL+ SL + + V+ Y +H P G + + + Sbjct: 93 ELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAME 152 Query: 632 DAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKAACDE 811 + + GL KS+GVSN++ ++L ++ + P+ NQV + + + C Sbjct: 153 ECKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVC-NQVECHPYFNRSK---LLDFCKS 208 Query: 812 LGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQPLINKIRVIGGSYDKTP 991 I L+AYS A G+ K P + D + + + + +TP Sbjct: 209 KDIVLVAYS--ALGSQRDKRW-----VDPNSPVLLEDPV---------LCALAKKHKRTP 252 Query: 992 TQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREV 1147 + L + + +G VV + + N ++ RE + LT +++ + + R + Sbjct: 253 ALIALRYQLQRG-VVVLAKSYNEQRIRENVQVFEFQLTAEDMRAIDGLNRNL 303
>Q4VCS5:AMOT_HUMAN Angiomotin - Homo sapiens (Human)| Length = 1084 Score = 32.0 bits (71), Expect = 6.2 Identities = 41/173 (23%), Positives = 69/173 (39%), Gaps = 9/173 (5%) Frame = -3 Query: 570 STEETPRRESEPFSAEITLPRPNLHGRAANFVAMATSTFSFSCLSLINLPSRLSEFIAPD 391 ST+ ES +A + P AA A+ + + + + P ++ AP Sbjct: 863 STQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPA 922 Query: 390 T---PAPYTSAVSKKVIP------LSTLASNAPLASLSFLSSHWKSFQ*VVSPQDQAPMP 238 P+P T+A + + + AS A A+++ ++ + Q + P P Sbjct: 923 AAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAP 982 Query: 237 SLVTATPDAPSIALLPSSTAAPSDVTARGGRNPAVRRWPRSGRQPQHPAPPAT 79 +LV A + A P+ T AP+ A PA P + Q + PA PAT Sbjct: 983 ALVPVPAPAAAQASAPAQTQAPTSAPA-VAPTPAPTPTP-AVAQAEVPASPAT 1033
>Q9BYB0:SHAN3_HUMAN SH3 and multiple ankyrin repeat domains protein 3 - Homo sapiens| (Human) Length = 1741 Score = 31.6 bits (70), Expect = 8.0 Identities = 16/32 (50%), Positives = 20/32 (62%), Gaps = 2/32 (6%) Frame = -1 Query: 1073 PGPAPRSLPPGSAP--RCPGK*ASSEPPELGF 984 P P+PR+ PPG P PG+ +S E PEL F Sbjct: 1251 PLPSPRAQPPGGTPADAGPGQGSSEEEPELVF 1282
>Q9NTZ6:RBM12_HUMAN RNA-binding protein 12 - Homo sapiens (Human)| Length = 932 Score = 31.6 bits (70), Expect = 8.0 Identities = 40/150 (26%), Positives = 59/150 (39%), Gaps = 21/150 (14%) Frame = -3 Query: 438 SLINLPSRLSEFIAPDTPAPYTSAVS-----KKVIPLST--LASNAPLASLSFLSSHWKS 280 S +NLP+ +S F P +P+ T+ S K + ST + + P SF S + S Sbjct: 115 SRVNLPTTVSNFNNP-SPSVVTATTSVHESNKNIQTFSTASVGTAPPNMGASFGSPTFSS 173 Query: 279 -FQ*VVSPQDQAPMPSL-----VTATPDAPSIALLPSSTAAPS--------DVTARGGRN 142 SP + P P + + + P PSI +P P+ + Sbjct: 174 TVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVP 233 Query: 141 PAVRRWPRSGRQPQHPAPPATCRAIADGSG 52 P P SG P +P P A A +GSG Sbjct: 234 PMTPLPPMSGMPPLNPPPVAPLPAGMNGSG 263
>Q43402:OLNB6_BRANA Oleosin-B6 - Brassica napus (Rape)| Length = 375 Score = 31.6 bits (70), Expect = 8.0 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 8/70 (11%) Frame = -3 Query: 267 VSPQDQAP--------MPSLVTATPDAPSIALLPSSTAAPSDVTARGGRNPAVRRWPRSG 112 V+P++ P P A P+AP+ P++ AAP+ A PA P + Sbjct: 189 VNPENNPPPAGAPPTGSPPAAPAAPEAPAAPAAPAAPAAPAAPAA-----PAAPEDPAAP 243 Query: 111 RQPQHPAPPA 82 P+ PA PA Sbjct: 244 AAPEAPATPA 253
>Q8WXI7:MUC16_HUMAN Mucin-16 - Homo sapiens (Human)| Length = 22152 Score = 31.6 bits (70), Expect = 8.0 Identities = 30/108 (27%), Positives = 46/108 (42%) Frame = -3 Query: 462 STFSFSCLSLINLPSRLSEFIAPDTPAPYTSAVSKKVIPLSTLASNAPLASLSFLSSHWK 283 STF F LS ++ + S A T + A + + + L T+ S A + L F H Sbjct: 3727 STFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLETMISPAT-SQLPFSIGHIT 3785 Query: 282 SFQ*VVSPQDQAPMPSLVTATPDAPSIALLPSSTAAPSDVTARGGRNP 139 S V+P A + + PD S +ST P+ +A G+ P Sbjct: 3786 S---AVTPAAMARSSGVTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVP 3830
>Q3TLR7:DTL_MOUSE Denticleless protein homolog - Mus musculus (Mouse)| Length = 729 Score = 31.6 bits (70), Expect = 8.0 Identities = 33/133 (24%), Positives = 50/133 (37%), Gaps = 1/133 (0%) Frame = -3 Query: 447 SCLSLINLPSRLSEFIAPDTPAPYTSAVSKKVIPLSTLASNAPLASLSFLSSHWKSFQ*V 268 SC + LPS F TPA S+VS++ S S PL+S +W + Sbjct: 452 SCAGDLPLPSSTPTFSVKTTPATTRSSVSRRGSISS--VSPKPLSSFKMSLRNWVT---- 505 Query: 267 VSPQDQAPMPSLVTATP-DAPSIALLPSSTAAPSDVTARGGRNPAVRRWPRSGRQPQHPA 91 +P P+ + T +P AL+P S + RN RR S + Sbjct: 506 RTPSSSPPVTPPASETKISSPRKALIPVSQKSSQADACSESRNRVKRRLDSSCLESVKQK 565 Query: 90 PPATCRAIADGSG 52 +C + + G Sbjct: 566 CVKSCNCVTELDG 578
>Q99280:CY43_TRYBB Receptor-type adenylate cyclase GRESAG 4.3 - Trypanosoma brucei| brucei Length = 1229 Score = 31.6 bits (70), Expect = 8.0 Identities = 22/76 (28%), Positives = 35/76 (46%) Frame = -3 Query: 471 MATSTFSFSCLSLINLPSRLSEFIAPDTPAPYTSAVSKKVIPLSTLASNAPLASLSFLSS 292 + T+ F +++ LP FI P TP P+ ++ S+ VI LS +++LSS Sbjct: 537 IVTAVFGIVTKAVLGLPGLT--FIDPITPTPHLNSFSRNVIHLSPTLEQQLYVLVNYLSS 594 Query: 291 HWKSFQ*VVSPQDQAP 244 F V +AP Sbjct: 595 IRADFPNCVIRGGEAP 610
>P82809:AK1CD_MESAU Aldo-keto reductase family 1 member C13 - Mesocricetus auratus| (Golden hamster) Length = 322 Score = 31.6 bits (70), Expect = 8.0 Identities = 38/180 (21%), Positives = 83/180 (46%), Gaps = 3/180 (1%) Frame = +2 Query: 620 DGLADAYEQGLVKSVGVSNYSEKRLRDAHDRLKKRGVPLASNQVNYSLIYRNPEENGVKA 799 + L + GLVKS+GVSN++ ++L ++ + P+ NQV +Y N ++ + Sbjct: 149 EALEKXXDAGLVKSIGVSNFNMRQLERILNKPGLKYKPVC-NQVECH-VYNN--QSKLLD 204 Query: 800 ACDELGITLIAYSPIAQGALTGKYTPANPPTGPRGRIYTSDFLSKLQP-LINKIRVIGGS 976 C I L+A+ + T +Y +++ + P L+N + GG+ Sbjct: 205 YCKSKDIVLVAFGALG----TQRY---------------KEWVDQDSPVLLNDPVLCGGA 245 Query: 977 --YDKTPTQVVLNWLICQGNVVPIPGAKNAEQAREFAGALGWLLTEQEVEELRSMAREVK 1150 ++P + L +L+ +G VVP+ + + +E + L+ ++++ L + + + Sbjct: 246 KXXXRSPALIALRYLVQRG-VVPLAQSFYESEMKENLQVFEFQLSPEDMKILDGLNKNFR 304 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 224,459,072 Number of extensions: 5029377 Number of successful extensions: 18888 Number of sequences better than 10.0: 151 Number of HSP's gapped: 18676 Number of HSP's successfully gapped: 159 Length of query: 454 Length of database: 100,686,439 Length adjustment: 117 Effective length of query: 337 Effective length of database: 68,593,924 Effective search space: 23116152388 Effective search space used: 23116152388 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
