ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf54c18 |
|---|---|
| Clone Library Name | barley_pub |
>Q5F478:ANR44_CHICK Ankyrin repeat domain-containing protein 44 - Gallus gallus (Chicken)| Length = 990 Score = 109 bits (273), Expect = 4e-23 Identities = 81/255 (31%), Positives = 121/255 (47%), Gaps = 1/255 (0%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G Q LLE N + S SPLH AA GHH+ + +LL+S V++++++ Sbjct: 539 AAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDE 598 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 +G+TAL A GH E V+ L+ A++ D + T +H + ++GH CLRL+L Sbjct: 599 KGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLL---- 654 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 + + +V+DA G TPL +A GH++ V LLL+ Sbjct: 655 ----------EVADNPDVTDAK----------------GQTPLMLAVAYGHIDAVSLLLE 688 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL- 1161 ASV DLL G T LH G+ C Q+L+ + ++ K+A G TPL Sbjct: 689 KEASVD--------AADLL--GCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLH 738 Query: 1162 MVAHSWHRNSIEEIL 1206 A H + E+L Sbjct: 739 FAAARGHATWLSELL 753 Score = 94.0 bits (232), Expect = 2e-18 Identities = 84/263 (31%), Positives = 122/263 (46%), Gaps = 38/263 (14%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA+ G IV LL GVEI+ N G TAL AC G VV L+ + AN+++ Sbjct: 208 TPLHAAASNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQ 267 Query: 715 TDYLNGGTAIHFAALHGH-ARCLRLVLAD---------------YVPSIPNFL--NQTKH 840 + NG T +HFAA H A CL L++ + ++ ++ +QT Sbjct: 268 PNN-NGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLI 326 Query: 841 RSSEEVSDADFDDD---------GLVKMVNWKADGG----------LTPLHMAALNGHVE 963 ++ E+ D D + G ++N G + PLH+AALN H + Sbjct: 327 QNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSD 386 Query: 964 CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNA 1143 C + LL G E+ D G T LH AA GGN C +LL + GA+ K+ Sbjct: 387 CCRKLLSSG---FEIDTPD-------SFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDK 436 Query: 1144 SGSTPL-MVAHSWHRNSIEEILS 1209 G TPL A + H + IE +++ Sbjct: 437 RGRTPLHYAAANCHFHCIETLVT 459 Score = 88.2 bits (217), Expect = 1e-16 Identities = 80/259 (30%), Positives = 116/259 (44%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 LV A GD +E R L+ + + +PLH A+ G +I+ LL+ SG +N Sbjct: 12 LVQAIFSGDPEEIRMLIYKTEDVNALDA--EKRTPLHVASFLGDADIIELLILSGARVNA 69 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ T L +A E VQ L+ +A+++ D N T +H AA + +C ++ Sbjct: 70 KDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDK-NWQTPLHVAAANKALKCAEII-- 126 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 +P + SS VSD GG T LH AALNGHVE V L Sbjct: 127 --IPML----------SSVNVSDR----------------GGRTALHHAALNGHVEMVNL 158 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGST 1155 LL GA+++ +D LH+AA G+ LLI GA + K+ G T Sbjct: 159 LLAKGANINAFDKKD----------RRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYT 208 Query: 1156 PLMVAHSWHRNSIEEILSN 1212 PL A S + +I + L N Sbjct: 209 PLHAAASNGQINIVKHLLN 227 Score = 85.5 bits (210), Expect = 8e-16 Identities = 74/222 (33%), Positives = 106/222 (47%), Gaps = 6/222 (2%) Frame = +1 Query: 523 GGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GGR + LH+AA GH E+V+LLL G IN + + + AL A GH EVV L+ A Sbjct: 139 GGRTA-LHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGA 197 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLR--LVLADYVPSIPNFLNQTKHRSSEEVSDA--- 867 + D G T +H AA +G ++ L L + + + N H + D+ Sbjct: 198 EVTCKD-KKGYTPLHAAASNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVN 256 Query: 868 DFDDDGLVKMVNWKADGGLTPLHMAALNGH-VECVQLLLDLGASVSEVTIEDGTTIDLLG 1044 + D G VN + G TPLH AA + H C++LL++ GA V+ + +D Sbjct: 257 ELIDYG--ANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVN-IQSKD-------- 305 Query: 1045 SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G +PLH A G Q LI G + + G+TPL VA Sbjct: 306 -GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVA 346 Score = 80.1 bits (196), Expect = 3e-14 Identities = 85/319 (26%), Positives = 130/319 (40%), Gaps = 39/319 (12%) Frame = +1 Query: 376 SMGFLSLVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAA 555 S GF +SFG + L +AA G+++ + L + G +PLHYAA Sbjct: 393 SSGFEIDTPDSFGRTC----LHAAAAGGNVECIKLLQSSGADFNKKDKRG--RTPLHYAA 446 Query: 556 AQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN---IHRTDYL 726 A H + L+ +G IN + G+T L A L + N + RT + Sbjct: 447 ANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNILGNSHENAEELERTSEM 506 Query: 727 ------------------------NGGTAIHFAALHGHARCLRLVL-----------ADY 801 G +H+AA +GH +CL L+L + Sbjct: 507 KEKEAALCLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSA 566 Query: 802 VPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLL 981 S + H + EV D ++ K + G T L +AA GH ECV+ L+ Sbjct: 567 TKSPLHLAAYNGHHQALEVLLQSLVD------LDIKDEKGRTALDLAAFKGHAECVEALI 620 Query: 982 DLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL 1161 GAS VT++D T TPLH + G+ C +LL+ N +A G TPL Sbjct: 621 SQGAS---VTVKDNVT------KRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPL 671 Query: 1162 MVAHSW-HRNSIEEILSNE 1215 M+A ++ H +++ +L E Sbjct: 672 MLAVAYGHIDAVSLLLEKE 690 Score = 79.7 bits (195), Expect = 4e-14 Identities = 74/256 (28%), Positives = 109/256 (42%), Gaps = 31/256 (12%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLE---SGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN 705 +PLH+AAA+GH +S LL+ S + +L++ +G T L AC GH ++ L+ Sbjct: 735 TPLHFAAARGHATWLSELLQIALSEEDCSLKDNQGYTPLHWACYNGHENCIEVLL--EQK 792 Query: 706 IHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG 885 R Y N + +H A ++ H C +++ SI Sbjct: 793 FFRKFYGNSFSPLHCAVINDHENCASMLIGAIDASI------------------------ 828 Query: 886 LVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGT------------T 1029 VN K D G TPLH AA HVEC+QLLL A V+ V T Sbjct: 829 ----VNCKDDKGRTPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGA 884 Query: 1030 IDLL------------GSGSTPLHYAACGGNAVCCQLL---IARGANLAAKNASGSTPL- 1161 +D L +T LH A+ G+ C L+ I + + AKN S TPL Sbjct: 885 VDFLVNIAKADLTLRDKDSNTSLHLASSKGHEKCALLILDKIQEQSLINAKNNSLQTPLH 944 Query: 1162 MVAHSWHRNSIEEILS 1209 + A + + +EE+L+ Sbjct: 945 IAARNGLKMVVEELLA 960 Score = 70.1 bits (170), Expect = 4e-11 Identities = 66/254 (25%), Positives = 98/254 (38%), Gaps = 29/254 (11%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 N+PLH AA GH +++ L+ SG + L A H + + L+ I Sbjct: 340 NTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGFEID 399 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 D G T +H AA G+ C++L+ + S ADF Sbjct: 400 TPDSF-GRTCLHAAAAGGNVECIKLL---------------------QSSGADF------ 431 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYA 1071 N K G TPLH AA N H C++ L+ GA+++E G TPLHYA Sbjct: 432 ---NKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETD----------DWGRTPLHYA 478 Query: 1072 ACG---------GN-------------------AVCCQLLIARGANLAAKNASGSTPLMV 1167 A GN A+C + L+ AN + ++ G + Sbjct: 479 AASDMDRKKNILGNSHENAEELERTSEMKEKEAALCLEFLLQNDANPSIQDKEGYNTVHY 538 Query: 1168 AHSW-HRNSIEEIL 1206 A ++ HR +E +L Sbjct: 539 AAAYGHRQCLELLL 552 Score = 64.3 bits (155), Expect = 2e-09 Identities = 50/162 (30%), Positives = 74/162 (45%), Gaps = 4/162 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA H E + LLL ++N ++ G+TALM A Q GH V L+ NI + Sbjct: 838 TPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGAVDFLV----NIAK 893 Query: 715 TDYL----NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 D + T++H A+ GH +C L+L +++ + Sbjct: 894 ADLTLRDKDSNTSLHLASSKGHEKCALLIL-------------------DKIQEQS---- 930 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEV 1008 ++N K + TPLH+AA NG V+ LL GA V V Sbjct: 931 ----LINAKNNSLQTPLHIAARNGLKMVVEELLAKGACVLAV 968
>Q8N8A2:ANR44_HUMAN Ankyrin repeat domain-containing protein 44 - Homo sapiens (Human)| Length = 944 Score = 109 bits (272), Expect = 5e-23 Identities = 82/255 (32%), Positives = 123/255 (48%), Gaps = 1/255 (0%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G Q LLE S G SPLH AA GHH+ + +LL+S V++++R+ Sbjct: 539 AAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDE 598 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 +G+TAL A GH E V+ L+ A+I D + T +H + ++GH CLRL+L Sbjct: 599 KGRTALDLAAFKGHTECVEALINQGASIFVKDNVTKRTPLHASVINGHTLCLRLLL---- 654 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 E++D + V+ K G TPL +A GH++ V LLL+ Sbjct: 655 ----------------EIADNP-------EAVDVKDAKGQTPLMLAVAYGHIDAVSLLLE 691 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL- 1161 A+V T+D+L G T LH G+ C Q+L+ + ++ K++ G TPL Sbjct: 692 KEANVD--------TVDIL--GCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLH 741 Query: 1162 MVAHSWHRNSIEEIL 1206 A H + E+L Sbjct: 742 YAAARGHATWLSELL 756 Score = 92.4 bits (228), Expect = 7e-18 Identities = 83/263 (31%), Positives = 122/263 (46%), Gaps = 38/263 (14%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA+ G +V LL GVEI+ N G TAL AC G VV L+ + AN+++ Sbjct: 208 TPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQ 267 Query: 715 TDYLNGGTAIHFAALHGH-ARCLRLVLAD---------------YVPSIPNFL--NQTKH 840 + NG T +HFAA H A CL L++ + ++ ++ +QT Sbjct: 268 PNN-NGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLI 326 Query: 841 RSSEEVSDADFDDD---------GLVKMVNWKADGG----------LTPLHMAALNGHVE 963 ++ E+ D D + G ++N G + PLH+AALN H + Sbjct: 327 QNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSD 386 Query: 964 CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNA 1143 C + LL G + T D G T LH AA GGN C +LL + GA+ K+ Sbjct: 387 CCRKLLSSGFEID--------TPDKF--GRTCLHAAAAGGNVECIKLLQSSGADFHKKDK 436 Query: 1144 SGSTPL-MVAHSWHRNSIEEILS 1209 G TPL A + H + IE +++ Sbjct: 437 CGRTPLHYAAANCHFHCIETLVT 459 Score = 90.9 bits (224), Expect = 2e-17 Identities = 76/247 (30%), Positives = 108/247 (43%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 LV A GD +E R L+ + + + +PLH AA G EI+ LL+ SG +N Sbjct: 12 LVQAIFSGDPEEIRMLIHKTEDVNTLDS--EKRTPLHVAAFLGDAEIIELLILSGARVNA 69 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ T L +A E VQ L+ +A+++ D N T +H AA + +C +++ Sbjct: 70 KDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARD-KNWQTPLHVAAANKAVKCAEVIIP 128 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 L+ VN GG T LH AALNGHVE V L Sbjct: 129 ------------------------------LLSSVNVSDRGGRTALHHAALNGHVEMVNL 158 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGST 1155 LL GA+++ +D LH+AA G+ LLI GA + K+ G T Sbjct: 159 LLAKGANINAFDKKD----------RRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYT 208 Query: 1156 PLMVAHS 1176 PL A S Sbjct: 209 PLHAAAS 215 Score = 86.7 bits (213), Expect = 4e-16 Identities = 75/222 (33%), Positives = 106/222 (47%), Gaps = 6/222 (2%) Frame = +1 Query: 523 GGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GGR + LH+AA GH E+V+LLL G IN + + + AL A GH +VV L+ A Sbjct: 139 GGRTA-LHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGA 197 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLR--LVLADYVPSIPNFLNQTKHRSSEEVSDA--- 867 + D G T +H AA +G ++ L L + I + N H + DA Sbjct: 198 EVTCKD-KKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVN 256 Query: 868 DFDDDGLVKMVNWKADGGLTPLHMAALNGH-VECVQLLLDLGASVSEVTIEDGTTIDLLG 1044 + D G VN + G TPLH AA + H C++LL++ GA V+ + +D Sbjct: 257 ELIDYG--ANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVN-IQSKD-------- 305 Query: 1045 SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G +PLH A G Q LI G + + G+TPL VA Sbjct: 306 -GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVA 346 Score = 85.5 bits (210), Expect = 8e-16 Identities = 82/300 (27%), Positives = 131/300 (43%), Gaps = 37/300 (12%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLE---SGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 + +PLH + GH + LLLE + +++++ +GQT LM A YGH + V L+ Sbjct: 634 KRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKE 693 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 AN+ D L G TA+H + GH C++++L V + ++ R+ + A Sbjct: 694 ANVDTVDIL-GCTALHRGIMTGHEECVQMLLEQEVSIL---CKDSRGRTPLHYAAARGHA 749 Query: 880 DGLVKMVN---------WKADGGLTPLHMAALNGHVECVQLLLD-------LGASVSE-- 1005 L +++ +K + G TPLH A NG+ C+++LL+ +G + Sbjct: 750 TWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTPLH 809 Query: 1006 --VTIEDGTTIDLL-------------GSGSTPLHYAACGGNAVCCQLLIARGANLAAKN 1140 + + G LL G TPL AA + C QLL+ A + A + Sbjct: 810 CAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPVNAVD 869 Query: 1141 ASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPYLCLPLMSIMSIARE-CGWRYLNK 1317 SG T LM+A + +IL N + T+ L PL S E C L+K Sbjct: 870 NSGKTALMMAAENGQAGAVDILVNSAQADL-TVKDKDLNTPLHLACSKGHEKCALLILDK 928 Score = 73.9 bits (180), Expect = 2e-12 Identities = 71/271 (26%), Positives = 110/271 (40%), Gaps = 41/271 (15%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH A G L+++G EI+ + G T L A +YGH ++ TL+ A+ + Sbjct: 308 SPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAK 367 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLAD--YVPSIPNFLNQTKHRSSE----------EV 858 ++ +H AAL+ H+ C R +L+ + + F H ++ + Sbjct: 368 CG-IHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQS 426 Query: 859 SDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 S ADF K G TPLH AA N H C++ L+ GA+V+E Sbjct: 427 SGADFHK---------KDKCGRTPLHYAAANCHFHCIETLVTTGANVNETD--------- 468 Query: 1039 LGSGSTPLHYAACG---------GNA-------------------VCCQLLIARGANLAA 1134 G T LHYAA GNA +C + L+ AN + Sbjct: 469 -DWGRTALHYAAASDMDRNKTILGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSI 527 Query: 1135 KNASGSTPLMVAHSW-HRNSIEEILSNEPGG 1224 ++ G + A ++ HR +E +L G Sbjct: 528 RDKEGYNSIHYAAAYGHRQCLELLLERTNSG 558 Score = 72.8 bits (177), Expect = 5e-12 Identities = 73/260 (28%), Positives = 110/260 (42%), Gaps = 13/260 (5%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L+ A G + LLE + G + LH GH E V +LLE V I Sbjct: 674 LMLAVAYGHIDAVSLLLEKEANVDTVDILGC--TALHRGIMTGHEECVQMLLEQEVSILC 731 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN--GGTAIHFAALHGHARCLRLV 789 ++ RG+T L A GH + L+ + + + G T +H+A +G+ C+ ++ Sbjct: 732 KDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVL 791 Query: 790 LAD----------YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHM 939 L + P +N + +S + D +V+ + D G TPL Sbjct: 792 LEQKCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSS------IVSCRDDKGRTPLRA 845 Query: 940 AALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLI-AR 1116 AA HVEC+QLLL A V+ V SG T L AA G A +L+ + Sbjct: 846 AAFADHVECLQLLLRHSAPVNAVD----------NSGKTALMMAAENGQAGAVDILVNSA 895 Query: 1117 GANLAAKNASGSTPLMVAHS 1176 A+L K+ +TPL +A S Sbjct: 896 QADLTVKDKDLNTPLHLACS 915
>O15084:ANR28_HUMAN Ankyrin repeat domain-containing protein 28 - Homo sapiens (Human)| Length = 1086 Score = 103 bits (256), Expect = 4e-21 Identities = 67/209 (32%), Positives = 103/209 (49%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA GHH+ + +L++S +++++RN G+T L A GH E V L+ A+I Sbjct: 585 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILV 644 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 DY+ T IH AA +GH+ CLRL++ + P +++ ++ D + Sbjct: 645 KDYILKRTPIHAAATNGHSECLRLLIGNAEP-----------QNAVDIQDGN-------- 685 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 G TPL ++ LNGH +CV LL+ GA+V G T LH A Sbjct: 686 --------GQTPLMLSVLNGHTDCVYSLLNKGANVDAKD----------KWGRTALHRGA 727 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL 1161 G+ C L+ GA +++ G TP+ Sbjct: 728 VTGHEECVDALLQHGAKCLLRDSRGRTPI 756 Score = 89.0 bits (219), Expect = 7e-17 Identities = 79/266 (29%), Positives = 126/266 (47%), Gaps = 38/266 (14%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLL---ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 + +P+H AA GH E + LL+ E +++++ GQT LM + GH + V +L+ Sbjct: 650 KRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKG 709 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 AN+ D G TA+H A+ GH C+ +L + L ++ R+ +S A Sbjct: 710 ANVDAKDKW-GRTALHRGAVTGHEECVDALLQHGAKCL---LRDSRGRTPIHLSAACGHI 765 Query: 880 DGLVKMVNWKA----------DGGLTPLHMAALNGHVECVQLLLDL-------GASVSEV 1008 L ++ A + G T LH A NGH CV+LLL+ G + S + Sbjct: 766 GVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPL 825 Query: 1009 ---TIEDGT-----TIDLLGS---------GSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 I D ID LG+ G TPLH AA + C QLL++ A + + Sbjct: 826 HCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSV 885 Query: 1138 NASGSTPLMV-AHSWHRNSIEEILSN 1212 +++G TPLM+ A + N++E ++S+ Sbjct: 886 DSTGKTPLMMAAENGQTNTVEMLVSS 911 Score = 86.3 bits (212), Expect = 5e-16 Identities = 79/253 (31%), Positives = 119/253 (47%), Gaps = 8/253 (3%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 LV A +GD E RAL+ + + + +PLH AA G EI+ LL+ SG +N Sbjct: 45 LVQAIFNGDPDEVRALI-FKKEDVNFQD-NEKRTPLHAAAYLGDAEIIELLILSGARVNA 102 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ + T L +A E VQ L+ +A+++ D N T +H AA + +C + Sbjct: 103 KDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARD-KNWQTPLHIAAANKAVKCAEAL-- 159 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDG-LVKM-------VNWKADGGLTPLHMAALN 951 VP + N +N + + A F G +VK+ +N +H AA Sbjct: 160 --VPLLSN-VNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYM 216 Query: 952 GHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLA 1131 GH+E V+LL+ GA EVT +D + TPLH AA G + L+ G ++ Sbjct: 217 GHIEVVKLLVSHGA---EVTCKDKKSY-------TPLHAAASSGMISVVKYLLDLGVDMN 266 Query: 1132 AKNASGSTPLMVA 1170 NA G+TPL VA Sbjct: 267 EPNAYGNTPLHVA 279 Score = 84.3 bits (207), Expect = 2e-15 Identities = 76/239 (31%), Positives = 109/239 (45%), Gaps = 29/239 (12%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH+AA GH E+V LLL G IN + + + A+ A GH EVV+ L+ A + D Sbjct: 177 LHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKD 236 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVP-SIPNFLNQTKHR----SSEEVSDADFDDDG 885 T +H AA G ++ +L V + PN T + ++V + D G Sbjct: 237 -KKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCG 295 Query: 886 LVKMVNWKADGGLTPLHMAALNGH-VECVQLLLDLGASV--------------------- 999 + VN K + G TPLH AA + H C++LL+ GA V Sbjct: 296 AI--VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFS 353 Query: 1000 -SEVTIEDGTTIDLLG-SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 S+ I+ G ID +G+TPLH AA G+ + LI GA+ A + G PL +A Sbjct: 354 RSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLA 412 Score = 80.5 bits (197), Expect = 3e-14 Identities = 66/235 (28%), Positives = 103/235 (43%), Gaps = 2/235 (0%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH A G +++SG I+ + G T L A +YGH ++ TL+ A+ + Sbjct: 341 TPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAK 400 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 ++G +H AAL G + C R +L+ + FD Sbjct: 401 RG-IHGMFPLHLAALSGFSDCCRKLLS-----------------------SGFD------ 430 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 ++ D G T LH AA G++EC+ LLL+ GA ++ G +PLHYAA Sbjct: 431 -IDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD----------KFGRSPLHYAA 479 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS--IEEILSNEPGGQIR 1233 N C L+ GA++ + G TPL A + + +E +L N+ IR Sbjct: 480 ANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIR 534 Score = 79.3 bits (194), Expect = 6e-14 Identities = 77/281 (27%), Positives = 115/281 (40%), Gaps = 73/281 (25%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR-- 714 LH A GH E V LL+ G + LR+ RG+T + + GH V+ L+ A++ Sbjct: 723 LHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANP 782 Query: 715 -TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD-DGL 888 T +G TA+H+A +GH C+ L+L V +T+ + + A +D +G Sbjct: 783 ATADNHGYTALHWACYNGHETCVELLLEQEV------FQKTEGNAFSPLHCAVINDNEGA 836 Query: 889 VKM---------VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEV----------T 1011 +M VN G TPLH AA HVEC+QLLL A V+ V Sbjct: 837 AEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMA 896 Query: 1012 IEDG--TTIDLLGSGS-------------------------------------------- 1053 E+G T+++L S + Sbjct: 897 AENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATN 956 Query: 1054 ----TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 TPLH AA G + Q L+ +GA++ A + +G TP + Sbjct: 957 AALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPAL 997 Score = 66.2 bits (160), Expect = 5e-10 Identities = 61/235 (25%), Positives = 111/235 (47%), Gaps = 11/235 (4%) Frame = +1 Query: 538 PLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT 717 PLH AA G + LL SG +I+ + G+T L A G+ E + L+ A+ ++ Sbjct: 408 PLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKK 467 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM 897 D G + +H+AA + + +CL ++ + N L++ + +D D L + Sbjct: 468 DKF-GRSPLHYAAANCNYQCLFALVGS--GASVNDLDERGCTPLHYAATSDTDGKCLEYL 524 Query: 898 VNWKADGGL------TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS-- 1053 + A+ G+ +H +A GH C+QL+ + +V +E T L S + Sbjct: 525 LRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIAS--ETPLDVLMETSGTDMLSDSDNRA 582 Query: 1054 --TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILS 1209 +PLH AA G+ ++L+ +L +N+SG TPL + A H ++ +++ Sbjct: 583 TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLIN 637 Score = 40.4 bits (93), Expect = 0.030 Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRG---QTALMQACQYGHWEVVQTLMLFN 699 +N+ LH A ++GH L+LE + NL N QT L A + G VVQ L+ Sbjct: 923 KNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKG 982 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVP 807 A++ D A+ A A CL L+LA +P Sbjct: 983 ASVLAVDENGYTPALACAPNKDVADCLALILATMMP 1018
>Q505D1:ANR28_MOUSE Ankyrin repeat domain-containing protein 28 - Mus musculus (Mouse)| Length = 1053 Score = 102 bits (255), Expect = 5e-21 Identities = 67/209 (32%), Positives = 103/209 (49%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA GHH+ + +L++S +++++RN G+T L A GH E V L+ A+I Sbjct: 552 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILV 611 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 DY+ T IH AA +GH+ CLRL++ + P +++ ++ D + Sbjct: 612 KDYVLKRTPIHAAATNGHSECLRLLIGNAEP-----------QNAVDIQDGN-------- 652 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 G TPL ++ LNGH +CV LL+ GA+V G T LH A Sbjct: 653 --------GQTPLMLSVLNGHTDCVYSLLNKGANVDAKD----------KWGRTALHRGA 694 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL 1161 G+ C L+ GA +++ G TP+ Sbjct: 695 VTGHEECVDALLQHGAKCLLRDSRGRTPI 723 Score = 87.8 bits (216), Expect = 2e-16 Identities = 78/266 (29%), Positives = 126/266 (47%), Gaps = 38/266 (14%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLL---ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 + +P+H AA GH E + LL+ E +++++ GQT LM + GH + V +L+ Sbjct: 617 KRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKG 676 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 AN+ D G TA+H A+ GH C+ +L + L ++ R+ +S A Sbjct: 677 ANVDAKDKW-GRTALHRGAVTGHEECVDALLQHGAKCL---LRDSRGRTPIHLSAACGHI 732 Query: 880 DGLVKMVNWKA----------DGGLTPLHMAALNGHVECVQLLLDL-------GASVSEV 1008 L ++ + G T LH A NGH CV+LLL+ G + S + Sbjct: 733 GVLGALLQSATSVDANPAVVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSPL 792 Query: 1009 ---TIEDGT-----TIDLLGS---------GSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 I D ID LG+ G TPLH AA + C QLL+++ A + + Sbjct: 793 HCAVINDNEGAAEMLIDSLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSA 852 Query: 1138 NASGSTPLMV-AHSWHRNSIEEILSN 1212 +++G TPLM+ A + N++E ++S+ Sbjct: 853 DSTGKTPLMMAAENGQTNTVEMLVSS 878 Score = 85.5 bits (210), Expect = 8e-16 Identities = 79/253 (31%), Positives = 118/253 (46%), Gaps = 8/253 (3%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 LV A +GD E RAL+ + + + +PLH AA G EI+ LL+ SG +N Sbjct: 12 LVQAIFNGDPDEVRALI-FKKEDVNFQD-NEKRTPLHAAAYLGDAEIIELLILSGARVNA 69 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ + T L +A E VQ L+ +A+++ D N T +H AA + +C Sbjct: 70 KDSKWLTPLHRAVASCSEEAVQILLKHSADVNARD-KNWQTPLHIAAANKAVKCAE---- 124 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDG-LVKM-------VNWKADGGLTPLHMAALN 951 VP + N +N + + A F G +VK+ +N +H AA Sbjct: 125 SLVPLLSN-VNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYM 183 Query: 952 GHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLA 1131 GH+E V+LL+ GA EVT +D + TPLH AA G + L+ G ++ Sbjct: 184 GHIEVVKLLVSHGA---EVTCKDKKSY-------TPLHAAASSGMISVVKYLLDLGVDMN 233 Query: 1132 AKNASGSTPLMVA 1170 NA G+TPL VA Sbjct: 234 EPNAYGNTPLHVA 246 Score = 85.5 bits (210), Expect = 8e-16 Identities = 72/214 (33%), Positives = 98/214 (45%), Gaps = 2/214 (0%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA+ G +V LL+ GV++N N G T L AC G VV L+ AN+++ Sbjct: 208 TPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQ 267 Query: 715 TDYLNGGTAIHFAALHGH-ARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 + G T +HFAA H A CL L++ + AD Sbjct: 268 KNE-KGFTPLHFAAASTHGALCLELLVG---------------------NGAD------- 298 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLG-SGSTPLHY 1068 VN K+ G TPLHM AL+G S S+ I+ G ID +G+TPLH Sbjct: 299 --VNMKSKDGKTPLHMTALHGRF-----------SRSQTIIQSGAVIDCEDKNGNTPLHI 345 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 AA G+ + LI GA+ A + G PL +A Sbjct: 346 AARYGHELLINTLITSGADTAKRGIHGMFPLHLA 379 Score = 80.5 bits (197), Expect = 3e-14 Identities = 66/235 (28%), Positives = 103/235 (43%), Gaps = 2/235 (0%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH A G +++SG I+ + G T L A +YGH ++ TL+ A+ + Sbjct: 308 TPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAK 367 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 ++G +H AAL G + C R +L+ + FD Sbjct: 368 RG-IHGMFPLHLAALSGFSDCCRKLLS-----------------------SGFD------ 397 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 ++ D G T LH AA G++EC+ LLL+ GA ++ G +PLHYAA Sbjct: 398 -IDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD----------KFGRSPLHYAA 446 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS--IEEILSNEPGGQIR 1233 N C L+ GA++ + G TPL A + + +E +L N+ IR Sbjct: 447 ANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIR 501 Score = 79.0 bits (193), Expect = 8e-14 Identities = 74/276 (26%), Positives = 111/276 (40%), Gaps = 68/276 (24%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A GH E V LL+ G + LR+ RG+T + + GH V+ L+ ++ Sbjct: 690 LHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSATSVDANP 749 Query: 721 YL---NGGTAIHFAALHGHARCLRLVLA-DYVPSIPNFLNQTKH----RSSEEVSDADFD 876 + +G TA+H+A +GH C+ L+L D I H +E ++ D Sbjct: 750 AVVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSPLHCAVINDNEGAAEMLID 809 Query: 877 DDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSE----------VTIEDG- 1023 G +VN G TPLH AA HVEC+QLLL A V+ + E+G Sbjct: 810 SLG-ASIVNATDSKGRTPLHAAAFTDHVECLQLLLSQNAQVNSADSTGKTPLMMAAENGQ 868 Query: 1024 -TTIDLLGSGS------------------------------------------------T 1056 T+++L S + T Sbjct: 869 TNTVEMLVSSASADLTLQDKSKNTALHLACGKGHETSALLILEKITDRNLINATNAALQT 928 Query: 1057 PLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 PLH AA G + Q L+ +GA++ A + +G TP + Sbjct: 929 PLHVAARNGLTMVVQELLGKGASVLAVDENGYTPAL 964 Score = 66.2 bits (160), Expect = 5e-10 Identities = 61/235 (25%), Positives = 111/235 (47%), Gaps = 11/235 (4%) Frame = +1 Query: 538 PLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT 717 PLH AA G + LL SG +I+ + G+T L A G+ E + L+ A+ ++ Sbjct: 375 PLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKK 434 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM 897 D G + +H+AA + + +CL ++ + N L++ + +D D L + Sbjct: 435 DKF-GRSPLHYAAANCNYQCLFALVGS--GASVNDLDERGCTPLHYAATSDTDGKCLEYL 491 Query: 898 VNWKADGGL------TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS-- 1053 + A+ G+ +H +A GH C+QL+ + +V +E T L S + Sbjct: 492 LRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIAS--ETPLDVLMETSGTDMLSDSDNRA 549 Query: 1054 --TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILS 1209 +PLH AA G+ ++L+ +L +N+SG TPL + A H ++ +++ Sbjct: 550 TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLIN 604 Score = 40.0 bits (92), Expect = 0.039 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRG---QTALMQACQYGHWEVVQTLMLFN 699 +N+ LH A +GH L+LE + NL N QT L A + G VVQ L+ Sbjct: 890 KNTALHLACGKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKG 949 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVP 807 A++ D A+ A A CL L+LA +P Sbjct: 950 ASVLAVDENGYTPALACAPNKDVADCLALILATMMP 985
>Q502K3:ANR52_DANRE Ankyrin repeat domain-containing protein 52 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 1071 Score = 100 bits (249), Expect = 2e-20 Identities = 71/209 (33%), Positives = 101/209 (48%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA G +L+++G EI+ + G T L A +YGH ++ TLM A+ R Sbjct: 308 SPLHMAAIHGRFTRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTAR 367 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 ++G +H A L+G + C R +L S + S E V A FD Sbjct: 368 QG-IHGMFPLHLAVLYGSSDCCRKLL-----SSGQLYSIVLSMSKEHVLSAGFD------ 415 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 +N + G T LH AA G++EC+ LLL GA +++ G TPLHYAA Sbjct: 416 -INTPDNFGRTCLHAAASGGNIECLNLLLSSGADMNKKD----------KFGRTPLHYAA 464 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL 1161 G C +L+ GA + ++ SG TPL Sbjct: 465 ANGRYQCVVVLVGAGAEVNERDRSGCTPL 493 Score = 94.7 bits (234), Expect = 1e-18 Identities = 77/267 (28%), Positives = 119/267 (44%), Gaps = 2/267 (0%) Frame = +1 Query: 415 CSASGERLVS-AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 C+ G V AA G+ Q LLE G SPLH A GH E V++L+ Sbjct: 540 CNTKGYSAVHYAAAHGNKQNLELLLEMCFNTLGDKESNGSISPLHLAVESGHWECVTVLI 599 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 ESGV +++ + G++ L A Q GH V+ L+ +A+ ++ + +H AA +GH+ Sbjct: 600 ESGVCVDVCDPVGRSVLYLASQRGHSRCVELLLSQSASCLLAEHRSKWGPLHVAAANGHS 659 Query: 772 RCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALN 951 CLR++L +G +VN G TPL +A L Sbjct: 660 ECLRMLLC---------------------------SEGGADLVNVTDAEGQTPLMLAVLG 692 Query: 952 GHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLA 1131 GH +CV LLL+ GA ++D G T LH A G C L++ ++ Sbjct: 693 GHTDCVHLLLERGACPD---MKD-------RRGRTALHRGAVMGREDCLTALLSHNVSVL 742 Query: 1132 AKNASGSTPLMVAHS-WHRNSIEEILS 1209 +++ G + L +A S H + + +LS Sbjct: 743 SRDFQGRSALHLAASCGHADILSNLLS 769 Score = 87.0 bits (214), Expect = 3e-16 Identities = 68/230 (29%), Positives = 110/230 (47%), Gaps = 6/230 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PL A GH + V LLLE G ++++ RG+TAL + G + + L+ N ++ Sbjct: 684 TPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTALHRGAVMGREDCLTALLSHNVSVLS 743 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 D+ G +A+H AA GHA L +L+ S P +H + A + ++ Sbjct: 744 RDF-QGRSALHLAASCGHADILSNLLSAADHSQPQDPLTDRHGYTPAHWAAYHGHEDCLE 802 Query: 895 MV------NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGST 1056 ++ + + TPLH A +NGH +LLL+ S V I D G T Sbjct: 803 VLLELKPCSIQEGNPFTPLHCALINGHSGSAELLLESSVCNSLVNIRDA-------KGRT 855 Query: 1057 PLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 PLH AA + QL++ +GA++ A + SG + LMVA + ++ +L Sbjct: 856 PLHAAAVAEDVAGLQLVLRQGADIDAVDHSGRSALMVAADYGQSGAVALL 905 Score = 86.7 bits (213), Expect = 4e-16 Identities = 73/252 (28%), Positives = 119/252 (47%), Gaps = 10/252 (3%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA+ G + + LL L+ ++ P+H+AA GH E+V LL+ G + + ++ Sbjct: 147 AAQSGYQEMVKLLLNKGANLS--ASDKKDRQPIHWAAYLGHLEVVKLLVSQGSDKSCKDK 204 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 RG T L A GH +VV+ L+ A I + G TA+H A G +A+ + Sbjct: 205 RGYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAF-GNTALHVACYTGQE-----AVANEL 258 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKM---------VNWKADGGLTPLHMAALNGH 957 + +NQ HR + A +G + + VN ++ G +PLHMAA++G Sbjct: 259 VNRGANVNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAAIHGR 318 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGS-GSTPLHYAACGGNAVCCQLLIARGANLAA 1134 + S++ I++G ID + G+TPLH AA G+ + L+ GA+ A Sbjct: 319 F-----------TRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTAR 367 Query: 1135 KNASGSTPLMVA 1170 + G PL +A Sbjct: 368 QGIHGMFPLHLA 379 Score = 84.3 bits (207), Expect = 2e-15 Identities = 71/235 (30%), Positives = 113/235 (48%), Gaps = 9/235 (3%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH+AA G+ E+V LLL G ++ + + + + A GH EVV+ L+ ++ Sbjct: 142 APLHHAAQSGYQEMVKLLLNKGANLSASDKKDRQPIHWAAYLGHLEVVKLLVSQGSDKSC 201 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVP-SIPNFLNQTK-----HRSSEEVSDADFD 876 D G T +H AA GH ++ +L + PN T + E V++ + Sbjct: 202 KD-KRGYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYTGQEAVANELVN 260 Query: 877 DDGLVKMVNWKADGGLTPLHMAAL--NGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSG 1050 V N + G TPLH+AA+ NG + C++LL++ GA V+ + E G Sbjct: 261 RGANVNQPNHR---GYTPLHLAAVSTNGAL-CLELLVNNGADVNMQSKE----------G 306 Query: 1051 STPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW-HRNSIEEILSN 1212 +PLH AA G Q+LI G + + G+TPL VA + H I +++N Sbjct: 307 KSPLHMAAIHGRFTRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTN 361 Score = 79.7 bits (195), Expect = 4e-14 Identities = 72/265 (27%), Positives = 111/265 (41%), Gaps = 53/265 (20%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AAA GH ++V LL +G EI+ N G TAL AC G V L+ AN+++ Sbjct: 208 TPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYTGQEAVANELVNRGANVNQ 267 Query: 715 TDYLN---------------------------------GGTAIHFAALHGHARCLRLVLA 795 ++ G + +H AA+HG ++++ Sbjct: 268 PNHRGYTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAAIHGRFTRSQILIQ 327 Query: 796 D--YVPSIPNFLNQTKHRSSEE----------VSDADFDDDGLVKMVNWKADGGLTPLHM 939 + + + + N H +++ + AD G+ G+ PLH+ Sbjct: 328 NGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTARQGI---------HGMFPLHL 378 Query: 940 AALNGHVECVQLLLDLGASVS-------EVTIEDGTTIDLLGS-GSTPLHYAACGGNAVC 1095 A L G +C + LL G S E + G I+ + G T LH AA GGN C Sbjct: 379 AVLYGSSDCCRKLLSSGQLYSIVLSMSKEHVLSAGFDINTPDNFGRTCLHAAASGGNIEC 438 Query: 1096 CQLLIARGANLAAKNASGSTPLMVA 1170 LL++ GA++ K+ G TPL A Sbjct: 439 LNLLLSSGADMNKKDKFGRTPLHYA 463 Score = 78.2 bits (191), Expect = 1e-13 Identities = 73/256 (28%), Positives = 114/256 (44%), Gaps = 24/256 (9%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AAA V LL +N+ + G+ L A Q G+ E+V+ L+ AN+ Sbjct: 109 TPLHIAAANRATRCVETLLPHVSSLNMADRTGRAPLHHAAQSGYQEMVKLLLNKGANLSA 168 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 +D + IH+AA GH ++L+++ + SD D Sbjct: 169 SDKKDR-QPIHWAAYLGHLEVVKLLVS-------------------QGSDKSCKDKR--- 205 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSE-------------VTIEDGTTID 1035 G TPLH AA +GHV+ V+ LL GA + E T ++ + Sbjct: 206 --------GYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYTGQEAVANE 257 Query: 1036 LLGSGS----------TPLHYAACGGN-AVCCQLLIARGANLAAKNASGSTPLMVAHSWH 1182 L+ G+ TPLH AA N A+C +LL+ GA++ ++ G +PL +A Sbjct: 258 LVNRGANVNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAAIHG 317 Query: 1183 RNSIEEILSNEPGGQI 1230 R + +IL + GG+I Sbjct: 318 RFTRSQILI-QNGGEI 332 Score = 62.4 bits (150), Expect = 7e-09 Identities = 61/221 (27%), Positives = 93/221 (42%), Gaps = 3/221 (1%) Frame = +1 Query: 523 GGRNSPLHYAAAQGHHEIVSLLLESGV---EINLRNYRGQTALMQACQYGHWEVVQTLML 693 G +PLH A GH LLLES V +N+R+ +G+T L A +Q ++ Sbjct: 815 GNPFTPLHCALINGHSGSAELLLESSVCNSLVNIRDAKGRTPLHAAAVAEDVAGLQLVLR 874 Query: 694 FNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADF 873 A+I D+ +G +A+ AA +G + + L+L HR+ ++S D Sbjct: 875 QGADIDAVDH-SGRSALMVAADYGQSGAVALLL---------------HRAKADLSLLDV 918 Query: 874 DDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS 1053 + + T LH+A H C L+L + + + T L Sbjct: 919 NKN--------------TALHLACSKAHEMCAMLILK---EIHNPILINATNSML----Q 957 Query: 1054 TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHS 1176 PLH AA G A Q L+ RGA + A + G TP + S Sbjct: 958 MPLHIAARNGLATVVQALLNRGATVLAVDEEGHTPALACAS 998 Score = 41.6 bits (96), Expect = 0.014 Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 24/128 (18%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVS----------------------EVT 1011 VN K LTPLH AA + + V LLL GA V+ E Sbjct: 67 VNAKDHVWLTPLHRAAASRNERAVGLLLRKGADVTARDKYWQTPLHIAAANRATRCVETL 126 Query: 1012 IEDGTTIDLLG-SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHR 1185 + +++++ +G PLH+AA G +LL+ +GANL+A + P+ A+ H Sbjct: 127 LPHVSSLNMADRTGRAPLHHAAQSGYQEMVKLLLNKGANLSASDKKDRQPIHWAAYLGHL 186 Query: 1186 NSIEEILS 1209 ++ ++S Sbjct: 187 EVVKLLVS 194 Score = 38.1 bits (87), Expect = 0.15 Identities = 37/132 (28%), Positives = 55/132 (41%), Gaps = 3/132 (2%) Frame = +1 Query: 424 SGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLE--- 594 SG + A D A ALL + + +N+ LH A ++ H L+L+ Sbjct: 885 SGRSALMVAADYGQSGAVALLLHRAKADLSLLDVNKNTALHLACSKAHEMCAMLILKEIH 944 Query: 595 SGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR 774 + + IN N Q L A + G VVQ L+ A + D A+ A+ A Sbjct: 945 NPILINATNSMLQMPLHIAARNGLATVVQALLNRGATVLAVDEEGHTPALACASNKAVAD 1004 Query: 775 CLRLVLADYVPS 810 CL L+L+ PS Sbjct: 1005 CLALILSTMKPS 1016 Score = 32.7 bits (73), Expect = 6.3 Identities = 27/78 (34%), Positives = 36/78 (46%) Frame = +1 Query: 928 PLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLL 1107 PL A N + + V+L L V+ + E TPLH AA G+ LL Sbjct: 11 PLVQAIFNRNADEVKLFLHKKDEVNALDQER----------RTPLHAAAWLGDVHIMDLL 60 Query: 1108 IARGANLAAKNASGSTPL 1161 I+ GAN+ AK+ TPL Sbjct: 61 ISAGANVNAKDHVWLTPL 78
>Q01484:ANK2_HUMAN Ankyrin-2 - Homo sapiens (Human)| Length = 3924 Score = 97.1 bits (240), Expect = 3e-19 Identities = 84/273 (30%), Positives = 130/273 (47%), Gaps = 9/273 (3%) Frame = +1 Query: 415 CSASG-ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 C+ +G L AA++G + + LL + + G N+ LH A+ G E+V +L+ Sbjct: 60 CNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG--NTALHIASLAGQAEVVKVLV 117 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 + G IN ++ G T L A Q H +VV+ L+ AN T +G T + A GH Sbjct: 118 KEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN-QSTATEDGFTPLAVALQQGHN 176 Query: 772 RCLRLVLAD------YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM-VNWKADGGLTP 930 + + ++L + +P++ + +S+ + D + D KM VN + G TP Sbjct: 177 QAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTP 236 Query: 931 LHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLI 1110 LH+AA G+V LLL+ GA+V +G TPLH A+ GN +LL+ Sbjct: 237 LHIAAHYGNVNVATLLLNRGAAVDFTA----------RNGITPLHVASKRGNTNMVKLLL 286 Query: 1111 ARGANLAAKNASGSTPL-MVAHSWHRNSIEEIL 1206 RG + AK G TPL A S H +E +L Sbjct: 287 DRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL 319 Score = 83.2 bits (204), Expect = 4e-15 Identities = 76/251 (30%), Positives = 114/251 (45%), Gaps = 9/251 (3%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRN--SPLHYAAAQGHHEIVSLLLESGVEINLR 618 AA G++ A LL + F RN +PLH A+ +G+ +V LLL+ G +I+ + Sbjct: 240 AAHYGNVNVATLLLNRGAAV----DFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAK 295 Query: 619 NYRGQTALMQACQYGHWEVVQTLMLFNAN-IHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 G T L A + GH +VV+ L+ A + RT NG + +H AA H C++ +L Sbjct: 296 TRDGLTPLHCAARSGHDQVVELLLERGAPLLARTK--NGLSPLHMAAQGDHVECVKHLLQ 353 Query: 796 DYVP------SIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGH 957 P L+ H V+ D N +A G TPLH+A Sbjct: 354 HKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRA---NPNARALNGFTPLHIACKKNR 410 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 ++ ++LL+ GAS+ +T SG TP+H AA G+ LL+ GA+ Sbjct: 411 IKVMELLVKYGASIQAIT----------ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVT 460 Query: 1138 NASGSTPLMVA 1170 N G T L +A Sbjct: 461 NIRGETALHMA 471 Score = 80.9 bits (198), Expect = 2e-14 Identities = 78/291 (26%), Positives = 126/291 (43%), Gaps = 35/291 (12%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A+R G + + LL++ +T G +PLH +A +G ++ S+LLE+G +L Sbjct: 504 ASRLGKTEIVQLLLQHMAHPDAATTNG--YTPLHISAREGQVDVASVLLEAGAAHSLATK 561 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLAD-- 798 +G T L A +YG +V + L+ A NG T +H AA + + + L+L Sbjct: 562 KGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGK-NGLTPLHVAAHYDNQKVALLLLEKGA 620 Query: 799 ---------YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALN 951 Y P L+ ++ +++ + +V + G+TPLH+A+ Sbjct: 621 SPHATAKNGYTP-----LHIAAKKNQMQIASTLLNYGAETNIVTKQ---GVTPLHLASQE 672 Query: 952 GHVECVQLLLDLGASVSEVTIEDGTTIDLLGS-----------------------GSTPL 1062 GH + V LLLD GA++ T T++ L G TPL Sbjct: 673 GHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPL 732 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILSN 1212 A GN L+ +GAN+ AK +G TPL A H + I +L + Sbjct: 733 IVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQH 783 Score = 80.1 bits (196), Expect = 3e-14 Identities = 79/260 (30%), Positives = 116/260 (44%), Gaps = 6/260 (2%) Frame = +1 Query: 445 AARDGDLQEARALLEYN------PRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE 606 AAR D + A LL+ + ++ T +PLH AA G+ + +LLL G Sbjct: 199 AARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAA 258 Query: 607 INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRL 786 ++ G T L A + G+ +V+ L+ I +G T +H AA GH + + L Sbjct: 259 VDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTR-DGLTPLHCAARSGHDQVVEL 317 Query: 787 VLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVEC 966 +L P L +TK+ GL+PLHMAA HVEC Sbjct: 318 LLERGAP----LLARTKN--------------------------GLSPLHMAAQGDHVEC 347 Query: 967 VQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNAS 1146 V+ LL A V +V T+D L T LH AA G+ +LL+ + AN A+ + Sbjct: 348 VKHLLQHKAPVDDV------TLDYL----TALHVAAHCGHYRVTKLLLDKRANPNARALN 397 Query: 1147 GSTPLMVAHSWHRNSIEEIL 1206 G TPL +A +R + E+L Sbjct: 398 GFTPLHIACKKNRIKVMELL 417 Score = 80.1 bits (196), Expect = 3e-14 Identities = 68/239 (28%), Positives = 104/239 (43%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +P+H AA GH IV LLL++G ++ N RG+TAL A + G EVV+ L L N + Sbjct: 433 TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL-LRNGALVD 491 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 T +H A+ G ++L+L +H + + + + Sbjct: 492 ARAREEQTPLHIASRLGKTEIVQLLL--------------QHMAHPDAATTN-------- 529 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 G TPLH++A G V+ +LL+ GA+ S T G TPLH AA Sbjct: 530 --------GYTPLHISAREGQVDVASVLLEAGAAHSLAT----------KKGFTPLHVAA 571 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPY 1251 G+ +LL+ R A + +G TPL VA + + +L + T + Y Sbjct: 572 KYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGY 630 Score = 79.3 bits (194), Expect = 6e-14 Identities = 73/231 (31%), Positives = 106/231 (45%) Frame = +1 Query: 478 ALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQ 657 ALL + ++T +PLH AA + +I S LL G E N+ +G T L A Q Sbjct: 612 ALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQ 671 Query: 658 YGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTK 837 GH ++V L+ ANIH + +G T++H AA ++ +AD + TK Sbjct: 672 EGHTDMVTLLLDKGANIHMSTK-SGLTSLHLAAQED-----KVNVADIL---------TK 716 Query: 838 HRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIE 1017 H + D D K+ G TPL +A G+V+ V LL GA+V+ T Sbjct: 717 HGA---------DQDAHTKL-------GYTPLIVACHYGNVKMVNFLLKQGANVNAKT-- 758 Query: 1018 DGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 +G TPLH AA G+ +L+ GA A A+G+T L +A Sbjct: 759 --------KNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIA 801 Score = 47.0 bits (110), Expect = 3e-04 Identities = 30/94 (31%), Positives = 47/94 (50%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L+ A G+++ LL+ + + G +PLH AA QGH I+++LL+ G + N Sbjct: 732 LIVACHYGNVKMVNFLLKQGANVNAKTKNG--YTPLHQAAQQGHTHIINVLLQHGAKPNA 789 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT 717 G TAL A + G+ VV TL + + T Sbjct: 790 TTANGNTALAIAKRLGYISVVDTLKVVTEEVTTT 823
>Q02357:ANK1_MOUSE Ankyrin-1 - Mus musculus (Mouse)| Length = 1862 Score = 96.3 bits (238), Expect = 5e-19 Identities = 80/257 (31%), Positives = 117/257 (45%), Gaps = 3/257 (1%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA+ L R LL+YN + + +PLH AA GHH + +LL+ G + N R Sbjct: 308 AAQGDHLDCVRLLLQYNAEIDDITL--DHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRAL 365 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLR-LVLADY 801 G T L AC+ H V++ L+ A+I +G T +H A+ GH ++ L+ Sbjct: 366 NGFTPLHIACKKNHIRVMELLLKTGASIDAVTE-SGLTPLHVASFMGHLPIVKNLLQRGA 424 Query: 802 VPSIPNFLNQTKHRSSEEVSDADFDDDGLVK--MVNWKADGGLTPLHMAALNGHVECVQL 975 P++ N +T + + L N KA TPLH AA GH V+L Sbjct: 425 SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKL 484 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGST 1155 LL+ GAS + T +G TPLH AA G+ L+ + A+ A G T Sbjct: 485 LLENGASPNLATT----------AGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFT 534 Query: 1156 PLMVAHSWHRNSIEEIL 1206 PL VA + + + E+L Sbjct: 535 PLHVAAKYGKVRLAELL 551 Score = 86.3 bits (212), Expect = 5e-16 Identities = 72/254 (28%), Positives = 113/254 (44%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AAR+ D + A LL+ +P S G +PLH AA + + LLL G +N Sbjct: 176 AARNDDTRTAAVLLQNDPNPDVLSKTGF--TPLHIAAHYENLNVAQLLLNRGASVNFTPQ 233 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G T L A + G+ +V+ L+ A I T + T +H AA +GH R ++L Sbjct: 234 NGITPLHIASRRGNVIMVRLLLDRGAQIE-TRTKDELTPLHCAARNGHVRISEILLDHGA 292 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 P + K GL+P+HMAA H++CV+LLL Sbjct: 293 P------------------------------IQAKTKNGLSPIHMAAQGDHLDCVRLLLQ 322 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 A + ++T++ TPLH AA G+ ++L+ +GA ++ +G TPL Sbjct: 323 YNAEIDDITLDH----------LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLH 372 Query: 1165 VAHSWHRNSIEEIL 1206 +A + + E+L Sbjct: 373 IACKKNHIRVMELL 386 Score = 81.3 bits (199), Expect = 2e-14 Identities = 81/272 (29%), Positives = 121/272 (44%), Gaps = 8/272 (2%) Frame = +1 Query: 415 CSASG-ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 C+ +G L A+++G ++ LL L + G N+ LH AA G E+V L+ Sbjct: 37 CNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG--NTALHIAALAGQDEVVRELV 94 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 G +N ++ +G T L A Q H EVV+ L+ AN +G T + A GH Sbjct: 95 NYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN-QNVATEDGFTPLAVALQQGHE 153 Query: 772 RCLRLVLADY-------VPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTP 930 + L +Y +P++ R++ + D + D L K G TP Sbjct: 154 NVV-AHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKT-------GFTP 205 Query: 931 LHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLI 1110 LH+AA ++ QLLL+ GASV+ +G TPLH A+ GN + +LL+ Sbjct: 206 LHIAAHYENLNVAQLLLNRGASVNFTP----------QNGITPLHIASRRGNVIMVRLLL 255 Query: 1111 ARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 RGA + + TPL A I EIL Sbjct: 256 DRGAQIETRTKDELTPLHCAARNGHVRISEIL 287 Score = 80.9 bits (198), Expect = 2e-14 Identities = 84/288 (29%), Positives = 131/288 (45%), Gaps = 32/288 (11%) Frame = +1 Query: 445 AARDGDLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLR 618 AAR G + LLE +P LA +T G ++PLH AA +GH + LLE Sbjct: 473 AARIGHTGMVKLLLENGASPNLA--TTAG--HTPLHTAAREGHVDTALALLEKEASQACM 528 Query: 619 NYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL-- 792 +G T L A +YG + + L+ +A+ + NG T +H A H + ++L+L Sbjct: 529 TKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAG-KNGLTPLHVAVHHNNLDIVKLLLPR 587 Query: 793 --ADYVPSIPNF--LNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHV 960 + + P+ + L+ ++ EV+ + G N ++ G+TPLH+AA GH Sbjct: 588 GGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGG---SANAESVQGVTPLHLAAQEGHT 644 Query: 961 ECVQLLLDLGAS----------------------VSEVTIEDGTTID-LLGSGSTPLHYA 1071 E V LLL A+ V++V I+ G T+D G TPLH A Sbjct: 645 EMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVA 704 Query: 1072 ACGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILSN 1212 + GN + L+ A++ AK G +PL A H + + +L N Sbjct: 705 SHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 752 Score = 76.6 bits (187), Expect = 4e-13 Identities = 74/261 (28%), Positives = 122/261 (46%), Gaps = 7/261 (2%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRN--SPLHYAAAQGHHEIVSLLLESGVEINLR 618 AA+ G ++ A LLE++ + G+N +PLH A + +IV LLL G + Sbjct: 539 AAKYGKVRLAELLLEHDA----HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 594 Query: 619 NYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLAD 798 + G T L A + EV ++L+ + + + + + G T +H AA GH + L+L+ Sbjct: 595 AWNGYTPLHIAAKQNQIEVARSLLQYGGSAN-AESVQGVTPLHLAAQEGHTEMVALLLSK 653 Query: 799 YVPSIPNFLNQTKHRSSEEVSDADFDD--DGLVK---MVNWKADGGLTPLHMAALNGHVE 963 N N++ VS D L+K V+ G TPLH+A+ G+++ Sbjct: 654 QANG--NLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIK 711 Query: 964 CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNA 1143 V+ LL A V+ T G +PLH AA G+ LL+ GA+ ++ Sbjct: 712 LVKFLLQHQADVNAKT----------KLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSS 761 Query: 1144 SGSTPLMVAHSWHRNSIEEIL 1206 +G+TPL +A S+ ++L Sbjct: 762 NGTTPLAIAKRLGYISVTDVL 782 Score = 63.9 bits (154), Expect = 3e-09 Identities = 75/255 (29%), Positives = 107/255 (41%), Gaps = 26/255 (10%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA G+ + L +GV+IN N G L A + GH ++V L L I T Sbjct: 15 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVEL-LHKEIILETTTKK 73 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV--- 900 G TA+H AAL G +R + V N Q++ + A + +VK + Sbjct: 74 GNTALHIAALAGQDEVVR----ELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 129 Query: 901 ----NWKADGGLTPLHMAALNGHVECVQLLLDLGAS------------------VSEVTI 1014 N + G TPL +A GH V L++ G + V + Sbjct: 130 GANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLL 189 Query: 1015 EDGTTIDLLG-SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS 1191 ++ D+L +G TPLH AA N QLL+ RGA++ +G TPL +A S N Sbjct: 190 QNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIA-SRRGNV 248 Query: 1192 IEEILSNEPGGQIRT 1236 I L + G QI T Sbjct: 249 IMVRLLLDRGAQIET 263
>Q5ZLC8:ANR52_CHICK Ankyrin repeat domain-containing protein 52 - Gallus gallus (Chicken)| Length = 1073 Score = 95.5 bits (236), Expect = 8e-19 Identities = 71/212 (33%), Positives = 98/212 (46%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA G +L+++G EI+ + G T L A +YGH ++ TLM A+ R Sbjct: 308 SPLHMAAIHGRFTRSQILIQNGSEIDCADKYGNTPLHVAARYGHELLISTLMTNGADTAR 367 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 ++ +H A L G + C R +L S + S+E V A FD Sbjct: 368 RG-IHDMFPLHLAVLFGFSDCCRKLL-----SSGQLYSIVSSLSNEHVLSAGFD------ 415 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 +N + G T LH AA G+VEC+ LLL GA + G TPLHYAA Sbjct: 416 -INTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRD----------KFGRTPLHYAA 464 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G+ C L+ GA++ + G TPL A Sbjct: 465 ANGSYQCTVTLVTAGASINEADCKGCTPLHYA 496 Score = 80.9 bits (198), Expect = 2e-14 Identities = 73/232 (31%), Positives = 113/232 (48%), Gaps = 8/232 (3%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH+A GH E+V+LLL G ++ + + + + A GH EV++ L+ A++ D Sbjct: 144 LHHAVHSGHLEMVNLLLNKGASLSTCDKKDRQPIHWAAFLGHLEVLKLLVARGADVMCKD 203 Query: 721 YLNGGTAIHFAALHGHARCLR--LVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 G T +H AA G +R L L + +F N H + DA ++ LV Sbjct: 204 -KKGYTLLHTAAASGQIEVVRHLLRLGVEIDEPNSFGNTALHIACYMGQDAVANE--LVN 260 Query: 895 M---VNWKADGGLTPLHMAAL--NGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTP 1059 VN + G TPLH AA+ NG + C++LL++ GA V+ + E G +P Sbjct: 261 YGANVNQPNEKGFTPLHFAAVSTNGAL-CLELLVNNGADVNFQSKE----------GKSP 309 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW-HRNSIEEILSN 1212 LH AA G Q+LI G+ + + G+TPL VA + H I +++N Sbjct: 310 LHMAAIHGRFTRSQILIQNGSEIDCADKYGNTPLHVAARYGHELLISTLMTN 361 Score = 79.7 bits (195), Expect = 4e-14 Identities = 69/234 (29%), Positives = 100/234 (42%), Gaps = 6/234 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA GH E + L E+ V +++R+++G+TAL A + G E V+ L A+ Sbjct: 586 SPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALYLATERGSTECVEVLTSHGASALV 645 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + T +H AA +G+ L L++ S E D D Sbjct: 646 KERKRKWTPLHAAAANGNTDSLHLLI----------------DSGERADITDVMD----- 684 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS-GSTPLHYA 1071 G TPL +A +NGHV+CV LLL E G+T D G T LH Sbjct: 685 ------IHGQTPLMLAIMNGHVDCVHLLL-----------EKGSTADAADKRGRTALHRG 727 Query: 1072 ACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWH-----RNSIEEILSNEP 1218 A G C L+ A + ++ G TP+ A + R ++ LS +P Sbjct: 728 AVTGCEDCLAALLDHDAFVLCRDFKGRTPIHFASACGHLEILRTLLQAALSTDP 781 Score = 79.3 bits (194), Expect = 6e-14 Identities = 69/253 (27%), Positives = 115/253 (45%), Gaps = 11/253 (4%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRN-SPLHYAAAQGHHEIVSLLLESGVEINLRN 621 A G L+ LL L ST ++ P+H+AA GH E++ LL+ G ++ ++ Sbjct: 147 AVHSGHLEMVNLLLNKGASL---STCDKKDRQPIHWAAFLGHLEVLKLLVARGADVMCKD 203 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADY 801 +G T L A G EVV+ L+ I + G TA+H A G +A+ Sbjct: 204 KKGYTLLHTAAASGQIEVVRHLLRLGVEIDEPNSF-GNTALHIACYMGQD-----AVANE 257 Query: 802 VPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM---------VNWKADGGLTPLHMAALNG 954 + + +NQ + + A +G + + VN+++ G +PLHMAA++G Sbjct: 258 LVNYGANVNQPNEKGFTPLHFAAVSTNGALCLELLVNNGADVNFQSKEGKSPLHMAAIHG 317 Query: 955 HVECVQLLLDLGASVSEVTIEDGTTIDLLGS-GSTPLHYAACGGNAVCCQLLIARGANLA 1131 + S++ I++G+ ID G+TPLH AA G+ + L+ GA+ A Sbjct: 318 RF-----------TRSQILIQNGSEIDCADKYGNTPLHVAARYGHELLISTLMTNGADTA 366 Query: 1132 AKNASGSTPLMVA 1170 + PL +A Sbjct: 367 RRGIHDMFPLHLA 379 Score = 77.0 bits (188), Expect = 3e-13 Identities = 74/262 (28%), Positives = 118/262 (45%), Gaps = 38/262 (14%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNY---RGQTALMQACQYGHWEVVQTLMLFNAN 705 +PLH AAA G+ + + LL++SG ++ + GQT LM A GH + V L+ + Sbjct: 653 TPLHAAAANGNTDSLHLLIDSGERADITDVMDIHGQTPLMLAIMNGHVDCVHLLLEKGST 712 Query: 706 IHRTDYLNGGTAIHFAALHGHARCLRLVL--------ADYVPSIP-NFLNQTKHRSS-EE 855 D G TA+H A+ G CL +L D+ P +F + H Sbjct: 713 ADAADK-RGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHFASACGHLEILRT 771 Query: 856 VSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASV------------ 999 + A D L +V++ G +P+H A+ +GH +C++LLL+ Sbjct: 772 LLQAALSTDPLDSVVDYS---GYSPMHWASYSGHEDCLELLLEHNPFAYLEGNPFTPLHC 828 Query: 1000 SEVTIEDGTT---IDLLGS---------GSTPLHYAACGGNAVCCQLLIARGANLAAKNA 1143 + + +D T ++ LG+ G TPLH AA N QLL+ A + + Sbjct: 829 AVINNQDSTAEMLVEALGAKIVNSRDAKGRTPLHAAAFADNIHGLQLLLRHQAEVDTTDK 888 Query: 1144 SGSTPLMVA-HSWHRNSIEEIL 1206 G TPLM+A + H ++E +L Sbjct: 889 LGRTPLMMASENGHTAAVEFLL 910 Score = 75.9 bits (185), Expect = 6e-13 Identities = 68/245 (27%), Positives = 108/245 (44%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 LV A + D++E R+LL + R +PLH AA G I+ LL+ SG +N Sbjct: 12 LVQAIFNRDVEEVRSLLNQKENINVLDQ--ERRTPLHTAAYIGDVAILELLILSGANVNA 69 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ T L +A + + + L+ +A+++ D T +H AA + +C+ ++ Sbjct: 70 KDTVWLTPLHRAAASRNEKALHLLLKHSADVNARDKY-WQTPLHVAAANRATKCVEAIIP 128 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 L+ VN G T LH A +GH+E V L Sbjct: 129 ------------------------------LLSTVNVADRTGRTALHHAVHSGHLEMVNL 158 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGST 1155 LL+ GAS+S +D P+H+AA G+ +LL+ARGA++ K+ G T Sbjct: 159 LLNKGASLSTCDKKD----------RQPIHWAAFLGHLEVLKLLVARGADVMCKDKKGYT 208 Query: 1156 PLMVA 1170 L A Sbjct: 209 LLHTA 213 Score = 69.3 bits (168), Expect = 6e-11 Identities = 69/256 (26%), Positives = 114/256 (44%), Gaps = 32/256 (12%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AAA + + + LLL+ ++N R+ QT L A + V+ ++ + ++ Sbjct: 76 TPLHRAAASRNEKALHLLLKHSADVNARDKYWQTPLHVAAANRATKCVEAIIPLLSTVNV 135 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADF-DDDGLV 891 D G TA+H A GH + L+L L+ + + + A F ++ Sbjct: 136 AD-RTGRTALHHAVHSGHLEMVNLLLNKGAS-----LSTCDKKDRQPIHWAAFLGHLEVL 189 Query: 892 KM-------VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTI------------ 1014 K+ V K G T LH AA +G +E V+ LL LG + E Sbjct: 190 KLLVARGADVMCKDKKGYTLLHTAAASGQIEVVRHLLRLGVEIDEPNSFGNTALHIACYM 249 Query: 1015 -EDGTTIDLLGSGS----------TPLHYAACGGN-AVCCQLLIARGANLAAKNASGSTP 1158 +D +L+ G+ TPLH+AA N A+C +LL+ GA++ ++ G +P Sbjct: 250 GQDAVANELVNYGANVNQPNEKGFTPLHFAAVSTNGALCLELLVNNGADVNFQSKEGKSP 309 Query: 1159 LMVAHSWHRNSIEEIL 1206 L +A R + +IL Sbjct: 310 LHMAAIHGRFTRSQIL 325 Score = 64.3 bits (155), Expect = 2e-09 Identities = 68/275 (24%), Positives = 112/275 (40%), Gaps = 67/275 (24%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A G + ++ LL+ + R+++G+T + A GH E+++TL+ + D Sbjct: 724 LHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHFASACGHLEILRTLLQAALSTDPLD 783 Query: 721 YL---NGGTAIHFAALHGHARCLRLVLAD----YVPSIP--------------------- 816 + +G + +H+A+ GH CL L+L Y+ P Sbjct: 784 SVVDYSGYSPMHWASYSGHEDCLELLLEHNPFAYLEGNPFTPLHCAVINNQDSTAEMLVE 843 Query: 817 ----NFLNQTKHRSSEEVSDADFDDD--GLVKMVNWKADG------GLTPLHMAALNGHV 960 +N + + A F D+ GL ++ +A+ G TPL MA+ NGH Sbjct: 844 ALGAKIVNSRDAKGRTPLHAAAFADNIHGLQLLLRHQAEVDTTDKLGRTPLMMASENGHT 903 Query: 961 ECVQLLL-DLGASVSEVTIEDGTTIDLLGS-----------GST---------------P 1059 V+ LL A+++ + + T + L S G T P Sbjct: 904 AAVEFLLYQAKANITVLDVNKNTALHLACSKGHEKCALLILGETQDLGLINASNSALQMP 963 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 LH AA G A Q L++RGA + A + G TP + Sbjct: 964 LHIAARNGLATVVQALLSRGATVLAVDEEGHTPAL 998 Score = 63.9 bits (154), Expect = 3e-09 Identities = 77/301 (25%), Positives = 113/301 (37%), Gaps = 56/301 (18%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L +AA G+++ LL L R FG +PLHYAAA G ++ L+ +G IN Sbjct: 427 LHAAASGGNVECLNLLLSSGADLRRRDKFG--RTPLHYAAANGSYQCTVTLVTAGASINE 484 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDY------------------------ 723 + +G T L A + +T + N H TD Sbjct: 485 ADCKGCTPLHYAAASDTYRRAET---HSGNSHDTDEEPLKESRMKEAFFCLEFLLDNGAD 541 Query: 724 -----LNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 G TA+H+AA +G+ + L L+L + E+V Sbjct: 542 PSLRDKQGYTAVHYAAAYGNRQNLELLL------------EMSFNCLEDVESTI------ 583 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDL----------GASVSEVTIEDGTT--I 1032 ++PLH+AA NGH E ++ L + G + + E G+T + Sbjct: 584 ----------PVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALYLATERGSTECV 633 Query: 1033 DLLGSGS------------TPLHYAACGGNAVCCQLLIARGAN---LAAKNASGSTPLMV 1167 ++L S TPLH AA GN LLI G + G TPLM+ Sbjct: 634 EVLTSHGASALVKERKRKWTPLHAAAANGNTDSLHLLIDSGERADITDVMDIHGQTPLML 693 Query: 1168 A 1170 A Sbjct: 694 A 694 Score = 35.8 bits (81), Expect = 0.74 Identities = 30/99 (30%), Positives = 43/99 (43%), Gaps = 3/99 (3%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVE---INLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 +N+ LH A ++GH + L+L + IN N Q L A + G VVQ L+ Sbjct: 924 KNTALHLACSKGHEKCALLILGETQDLGLINASNSALQMPLHIAARNGLATVVQALLSRG 983 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIP 816 A + D A+ A A CL L+L+ P P Sbjct: 984 ATVLAVDEEGHTPALACAPNKDVADCLALILSTMKPFPP 1022
>Q9Y2G4:ANKR6_HUMAN Ankyrin repeat domain-containing protein 6 - Homo sapiens (Human)| Length = 692 Score = 95.1 bits (235), Expect = 1e-18 Identities = 87/311 (27%), Positives = 148/311 (47%), Gaps = 9/311 (2%) Frame = +1 Query: 418 SASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLES 597 +A ERL+ AA G + L+ R+A T GR +PLH AA +GH +V +LL++ Sbjct: 8 AALSERLLVAAYKGQTENVVQLINKGARVA--VTKHGR-TPLHLAANKGHLPVVQILLKA 64 Query: 598 GVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARC 777 G ++++++ QTAL +A G+ E++ L+ + R D +G TA+H A+ HG ++ Sbjct: 65 GCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQD-KDGNTALHEASWHGFSQS 123 Query: 778 LRLVLADYVPSIPNFLNQTKHRSSE---EVSDADFDDDGLVKMVNWKAD----GGLTPLH 936 +L+ V + N L + K ++ ++ ++ + +AD G T LH Sbjct: 124 AKLL----VKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLH 179 Query: 937 MAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIAR 1116 +AA H+ ++LLL SV E +G T LH AA + ++L+ Sbjct: 180 VAARYNHLSIIRLLLTAFCSVHEKN----------QAGDTALHVAAALNHKKVAKILLEA 229 Query: 1117 GANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPYLCLPLMSIMSIAR-- 1290 GA+ N +G TPL A + + +L+ P G + +P S ++AR Sbjct: 230 GADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQGSVSAGDTP------SSEQAVARKE 283 Query: 1291 ECGWRYLNKSP 1323 E +L+ SP Sbjct: 284 EAREEFLSASP 294
>Q502M6:ANR29_DANRE Ankyrin repeat domain-containing protein 29 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 298 Score = 94.7 bits (234), Expect = 1e-18 Identities = 73/232 (31%), Positives = 100/232 (43%), Gaps = 23/232 (9%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 ++ L +A+ QGH+EIV LL E G + G TAL ACQ+GH VV TL+ AN+H Sbjct: 77 STALFFASQQGHNEIVKLLFEFGASTEFQTKDGGTALCAACQFGHSRVVDTLLKNGANVH 136 Query: 712 RTDYLN-GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 D LN G TA+ A+ GH +R +L+ Sbjct: 137 --DQLNDGATALFLASQEGHVNLIRQLLSSGA---------------------------- 166 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA----------------------SVS 1002 VN + G PL MAA GH E V++LL GA SV Sbjct: 167 --KVNQPREDGTAPLWMAAQMGHSEVVKVLLLRGADRDADRKDGSTALFKAAHKGHCSVM 224 Query: 1003 EVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTP 1158 E ++ ++ +L +GST LH A GG+ LL+ A+ A N + P Sbjct: 225 EELLKFSPSLGILKNGSTALHAAVMGGSLKAVDLLLKANADPALPNTNNELP 276 Score = 85.9 bits (211), Expect = 6e-16 Identities = 77/233 (33%), Positives = 120/233 (51%), Gaps = 9/233 (3%) Frame = +1 Query: 547 YAAAQGHHEIVSLLLESG-VEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDY 723 +AA +G+ ++ LLL SG V+++ ++ G TALM A GH+E V+ L++ A+I+ Sbjct: 15 WAARKGNLALLQLLLNSGRVDVDCKDAYGTTALMVASYSGHYECVRELIMQGADIN-LQR 73 Query: 724 LNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD----DGLV 891 G TA+ FA+ GH ++L L ++ S QTK + + F D L+ Sbjct: 74 ETGSTALFFASQQGHNEIVKL-LFEFGASTE---FQTKDGGTALCAACQFGHSRVVDTLL 129 Query: 892 K---MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 K V+ + + G T L +A+ GHV ++ LL GA V++ EDGT PL Sbjct: 130 KNGANVHDQLNDGATALFLASQEGHVNLIRQLLSSGAKVNQPR-EDGT---------APL 179 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLM-VAHSWHRNSIEEILSNEP 1218 AA G++ ++L+ RGA+ A GST L AH H + +EE+L P Sbjct: 180 WMAAQMGHSEVVKVLLLRGADRDADRKDGSTALFKAAHKGHCSVMEELLKFSP 232
>P16157:ANK1_HUMAN Ankyrin-1 - Homo sapiens (Human)| Length = 1881 Score = 94.0 bits (232), Expect = 2e-18 Identities = 78/257 (30%), Positives = 117/257 (45%), Gaps = 3/257 (1%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA+ L R LL+Y+ + + +PLH AA GHH + +LL+ G + N R Sbjct: 312 AAQGDHLDCVRLLLQYDAEIDDITL--DHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRAL 369 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLR-LVLADY 801 G T L AC+ H V++ L+ A+I +G T +H A+ GH ++ L+ Sbjct: 370 NGFTPLHIACKKNHVRVMELLLKTGASIDAVTE-SGLTPLHVASFMGHLPIVKNLLQRGA 428 Query: 802 VPSIPNFLNQTKHRSSEEVSDADFDDDGLVK--MVNWKADGGLTPLHMAALNGHVECVQL 975 P++ N +T + + L VN KA TPLH AA GH V+L Sbjct: 429 SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKL 488 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGST 1155 LL+ A+ + T +G TPLH AA G+ L+ + A+ A G T Sbjct: 489 LLENNANPNLATT----------AGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFT 538 Query: 1156 PLMVAHSWHRNSIEEIL 1206 PL VA + + + E+L Sbjct: 539 PLHVAAKYGKVRVAELL 555 Score = 86.3 bits (212), Expect = 5e-16 Identities = 72/254 (28%), Positives = 113/254 (44%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AAR+ D + A LL+ +P S G +PLH AA + + LLL G +N Sbjct: 180 AARNDDTRTAAVLLQNDPNPDVLSKTGF--TPLHIAAHYENLNVAQLLLNRGASVNFTPQ 237 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G T L A + G+ +V+ L+ A I T + T +H AA +GH R ++L Sbjct: 238 NGITPLHIASRRGNVIMVRLLLDRGAQIE-TKTKDELTPLHCAARNGHVRISEILLDHGA 296 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 P + K GL+P+HMAA H++CV+LLL Sbjct: 297 P------------------------------IQAKTKNGLSPIHMAAQGDHLDCVRLLLQ 326 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 A + ++T++ TPLH AA G+ ++L+ +GA ++ +G TPL Sbjct: 327 YDAEIDDITLDH----------LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLH 376 Query: 1165 VAHSWHRNSIEEIL 1206 +A + + E+L Sbjct: 377 IACKKNHVRVMELL 390 Score = 85.5 bits (210), Expect = 8e-16 Identities = 84/286 (29%), Positives = 128/286 (44%), Gaps = 30/286 (10%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AAR G + LLE N +T G ++PLH AA +GH E V LLE Sbjct: 477 AARIGHTNMVKLLLENNANPNLATTAG--HTPLHIAAREGHVETVLALLEKEASQACMTK 534 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL---- 792 +G T L A +YG V + L+ +A+ + NG T +H A H + ++L+L Sbjct: 535 KGFTPLHVAAKYGKVRVAELLLERDAHPNAAG-KNGLTPLHVAVHHNNLDIVKLLLPRGG 593 Query: 793 ADYVPSIPNF--LNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVEC 966 + + P+ + L+ ++ EV+ + G N ++ G+TPLH+AA GH E Sbjct: 594 SPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG---SANAESVQGVTPLHLAAQEGHAEM 650 Query: 967 VQLLLDLGAS----------------------VSEVTIEDGTTID-LLGSGSTPLHYAAC 1077 V LLL A+ V++V I+ G +D G TPLH A+ Sbjct: 651 VALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASH 710 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILSN 1212 GN + L+ A++ AK G +PL A H + + +L N Sbjct: 711 YGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 756 Score = 82.4 bits (202), Expect = 7e-15 Identities = 82/272 (30%), Positives = 121/272 (44%), Gaps = 8/272 (2%) Frame = +1 Query: 415 CSASG-ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 C+ +G L A+++G ++ LL L + G N+ LH AA G E+V L+ Sbjct: 41 CNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG--NTALHIAALAGQDEVVRELV 98 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 G +N ++ +G T L A Q H EVV+ L+ AN +G T + A GH Sbjct: 99 NYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN-QNVATEDGFTPLAVALQQGHE 157 Query: 772 RCLRLVLADY-------VPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTP 930 + L +Y +P++ R++ + D + D L K G TP Sbjct: 158 NVV-AHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKT-------GFTP 209 Query: 931 LHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLI 1110 LH+AA ++ QLLL+ GASV+ +G TPLH A+ GN + +LL+ Sbjct: 210 LHIAAHYENLNVAQLLLNRGASVNFTP----------QNGITPLHIASRRGNVIMVRLLL 259 Query: 1111 ARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 RGA + K TPL A I EIL Sbjct: 260 DRGAQIETKTKDELTPLHCAARNGHVRISEIL 291 Score = 77.8 bits (190), Expect = 2e-13 Identities = 75/261 (28%), Positives = 122/261 (46%), Gaps = 7/261 (2%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRN--SPLHYAAAQGHHEIVSLLLESGVEINLR 618 AA+ G ++ A LLE + + G+N +PLH A + +IV LLL G + Sbjct: 543 AAKYGKVRVAELLLERDA----HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598 Query: 619 NYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLAD 798 + G T L A + EV ++L+ + + + + + G T +H AA GHA + L+L+ Sbjct: 599 AWNGYTPLHIAAKQNQVEVARSLLQYGGSAN-AESVQGVTPLHLAAQEGHAEMVALLLSK 657 Query: 799 YVPSIPNFLNQTKHRSSEEVSDADFDD--DGLVK---MVNWKADGGLTPLHMAALNGHVE 963 N N++ V+ D L+K MV+ G TPLH+A+ G+++ Sbjct: 658 QANG--NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIK 715 Query: 964 CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNA 1143 V+ LL A V+ T G +PLH AA G+ LL+ GA+ ++ Sbjct: 716 LVKFLLQHQADVNAKT----------KLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSS 765 Query: 1144 SGSTPLMVAHSWHRNSIEEIL 1206 G+TPL +A S+ ++L Sbjct: 766 DGTTPLAIAKRLGYISVTDVL 786 Score = 63.9 bits (154), Expect = 3e-09 Identities = 75/255 (29%), Positives = 107/255 (41%), Gaps = 26/255 (10%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA G+ + L +GV+IN N G L A + GH ++V L L I T Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVEL-LHKEIILETTTKK 77 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV--- 900 G TA+H AAL G +R + V N Q++ + A + +VK + Sbjct: 78 GNTALHIAALAGQDEVVR----ELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 133 Query: 901 ----NWKADGGLTPLHMAALNGHVECVQLLLDLGAS------------------VSEVTI 1014 N + G TPL +A GH V L++ G + V + Sbjct: 134 GANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLL 193 Query: 1015 EDGTTIDLLG-SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS 1191 ++ D+L +G TPLH AA N QLL+ RGA++ +G TPL +A S N Sbjct: 194 QNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIA-SRRGNV 252 Query: 1192 IEEILSNEPGGQIRT 1236 I L + G QI T Sbjct: 253 IMVRLLLDRGAQIET 267
>Q8BTI7:ANR52_MOUSE Ankyrin repeat domain-containing protein 52 - Mus musculus (Mouse)| Length = 1076 Score = 93.6 bits (231), Expect = 3e-18 Identities = 75/230 (32%), Positives = 103/230 (44%) Frame = +1 Query: 481 LLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQY 660 LL N Y + G+ SPLH AA G +L+++G EI+ + G T L A +Y Sbjct: 291 LLVNNGADVNYQSKEGK-SPLHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAARY 349 Query: 661 GHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKH 840 GH ++ TLM A+ R ++ +H A L G + C R +L S + Sbjct: 350 GHELLISTLMTNGADTARRG-IHDMFPLHLAVLFGFSDCCRKLL-----SSGQLYSIVSS 403 Query: 841 RSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIED 1020 S+E V A FD +N G T LH AA G+VEC+ LLL GA + Sbjct: 404 LSNEHVLSAGFD-------INTPDSLGRTCLHAAASGGNVECLNLLLSSGADLRRRD--- 453 Query: 1021 GTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G TPLHYAA G+ C L+ GA + + G +PL A Sbjct: 454 -------KFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYA 496 Score = 85.1 bits (209), Expect = 1e-15 Identities = 73/263 (27%), Positives = 111/263 (42%), Gaps = 5/263 (1%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G+ Q LLE + SPLH AA GH E + L E+ V +++R++ Sbjct: 557 AAAYGNRQNLELLLEMSFNCLEDVESTVPVSPLHLAAYNGHCEALKTLAETLVNLDVRDH 616 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 +G+TAL A + G E V+ L A+ + T +H AA GH L L+ Sbjct: 617 KGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLL----- 671 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 ++ + +V DA G TPL +A +NGHV+CV LLL+ Sbjct: 672 ------IDSGERADITDVMDA----------------YGQTPLMLAIMNGHVDCVHLLLE 709 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 G++ + G T LH A G C L+ A + ++ G TP+ Sbjct: 710 KGSTADAADLR----------GRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIH 759 Query: 1165 VAHSWH-----RNSIEEILSNEP 1218 +A + R ++ LS +P Sbjct: 760 LASACGHTAVLRTLLQAALSTDP 782 Score = 80.5 bits (197), Expect = 3e-14 Identities = 66/216 (30%), Positives = 105/216 (48%), Gaps = 5/216 (2%) Frame = +1 Query: 538 PLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT 717 PLH+AA GH E++ LL+ G +++ ++ +G L A G EVV+ L+ A I Sbjct: 176 PLHWAAFLGHLEVLKLLVARGADLSCKDRKGYGLLHTAAASGQIEVVKHLLRMGAEIDEP 235 Query: 718 DYLNGGTAIHFAALHGH-ARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + G TA+H A G A + LV A + PN T + ++ + LV Sbjct: 236 NAF-GNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVN 294 Query: 895 M---VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS-GSTPL 1062 VN+++ G +PLHMAA++G + S++ I++G+ ID G+TPL Sbjct: 295 NGADVNYQSKEGKSPLHMAAIHGRF-----------TRSQILIQNGSEIDCADKFGNTPL 343 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 H AA G+ + L+ GA+ A + PL +A Sbjct: 344 HVAARYGHELLISTLMTNGADTARRGIHDMFPLHLA 379 Score = 79.3 bits (194), Expect = 6e-14 Identities = 72/232 (31%), Positives = 110/232 (47%), Gaps = 6/232 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 S LH+A GH E V+LLL G +N+ + + + L A GH EV++ L+ A++ Sbjct: 142 SALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLSC 201 Query: 715 TDYLNGGTAIHFAALHGHARCLR--LVLADYVPSIPNFLNQTKHRSSEEVSDA-DFDDDG 885 D G +H AA G ++ L + + F N H + DA + Sbjct: 202 KD-RKGYGLLHTAAASGQIEVVKHLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVN 260 Query: 886 LVKMVNWKADGGLTPLHMAAL--NGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTP 1059 VN D G TPLH+AA+ NG + C++LL++ GA V+ + E G +P Sbjct: 261 AGANVNQPNDKGFTPLHVAAVSTNGAL-CLELLVNNGADVNYQSKE----------GKSP 309 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW-HRNSIEEILSN 1212 LH AA G Q+LI G+ + + G+TPL VA + H I +++N Sbjct: 310 LHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTN 361 Score = 74.3 bits (181), Expect = 2e-12 Identities = 71/258 (27%), Positives = 109/258 (42%), Gaps = 13/258 (5%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L +AA G ++ + LL + + FG N+ LH A G + L+ +G +N Sbjct: 210 LHTAAASGQIEVVKHLLRMGAEIDEPNAFG--NTALHIACYLGQDAVAIELVNAGANVNQ 267 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL- 792 N +G T L A + + L++ N G + +H AA+HG ++++ Sbjct: 268 PNDKGFTPLHVAAVSTNGALCLELLVNNGADVNYQSKEGKSPLHMAAIHGRFTRSQILIQ 327 Query: 793 -ADYVPSIPNFLNQTKH---RSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHV 960 + F N H R E+ + +G D + PLH+A L G Sbjct: 328 NGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRGIHD--MFPLHLAVLFGFS 385 Query: 961 ECVQLLLDLGASVS-------EVTIEDGTTIDLLGS-GSTPLHYAACGGNAVCCQLLIAR 1116 +C + LL G S E + G I+ S G T LH AA GGN C LL++ Sbjct: 386 DCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDSLGRTCLHAAASGGNVECLNLLLSS 445 Query: 1117 GANLAAKNASGSTPLMVA 1170 GA+L ++ G TPL A Sbjct: 446 GADLRRRDKFGRTPLHYA 463 Score = 73.2 bits (178), Expect = 4e-12 Identities = 66/238 (27%), Positives = 105/238 (44%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 LV A D++E R+LL + R +PLH AA G I+ LLL SG +N Sbjct: 12 LVQAIFSRDVEEVRSLLSQKENINVLDQ--ERRTPLHAAAYVGDVPILQLLLMSGANVNA 69 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ T L +A + +V+ L+ +A+++ D L T +H AA + +C + Sbjct: 70 KDTLWLTPLHRAAASRNEKVLGLLLAHSADVNARDKL-WQTPLHVAAANRATKCAEALAP 128 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 L+ +N G + LH A +GH+E V L Sbjct: 129 ------------------------------LLSSLNVADRSGRSALHHAVHSGHLETVNL 158 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 LL+ GAS++ ++ PLH+AA G+ +LL+ARGA+L+ K+ G Sbjct: 159 LLNKGASLNVCDKKE----------RQPLHWAAFLGHLEVLKLLVARGADLSCKDRKG 206 Score = 64.3 bits (155), Expect = 2e-09 Identities = 67/248 (27%), Positives = 103/248 (41%), Gaps = 39/248 (15%) Frame = +1 Query: 535 SPLHYAAAQGHHE----------------------------IVSLLLESGVEINLRNYRG 630 SPLHYAAA + + LL++G + +LR+ +G Sbjct: 491 SPLHYAAASDTYRRAEPHTASSHDAEEDELLKESRRKEAFFCLEFLLDNGADPSLRDRQG 550 Query: 631 QTALMQACQYGHWEVVQTLMLFNAN-IHRTDYLNGGTAIHFAALHGHARCLR-------- 783 TA+ A YG+ + ++ L+ + N + + + +H AA +GH L+ Sbjct: 551 YTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTVPVSPLHLAAYNGHCEALKTLAETLVN 610 Query: 784 LVLADYVPSIPNFLNQTKHRSSE--EVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGH 957 L + D+ FL T+ S+E EV A L+K K TPLH AA +GH Sbjct: 611 LDVRDHKGRTALFL-ATERGSTECVEVLTA-HGASALIKERKRK----WTPLHAAAASGH 664 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 + + LL+D G + D G TPL A G+ C LL+ +G+ A Sbjct: 665 TDSLHLLIDSGERADITDVMD-------AYGQTPLMLAIMNGHVDCVHLLLEKGSTADAA 717 Query: 1138 NASGSTPL 1161 + G T L Sbjct: 718 DLRGRTAL 725 Score = 61.2 bits (147), Expect = 2e-08 Identities = 51/165 (30%), Positives = 73/165 (44%), Gaps = 1/165 (0%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML-FNANIH 711 +PLH AA + + +LL+ E+N ++ G+TALM A + G V+ L+ A++ Sbjct: 860 TPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAESGQTAAVEFLLYRGKADLT 919 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 D N TA+H A GH +C ++L A+ D GL+ Sbjct: 920 VLDE-NKNTALHLACSKGHEKCALMIL------------------------AETQDLGLI 954 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGT 1026 N PLH+AA NG VQ LL GA+V V E T Sbjct: 955 NATNSALQ---MPLHIAARNGLASVVQALLSRGATVLAVDEEGHT 996 Score = 56.2 bits (134), Expect = 5e-07 Identities = 59/222 (26%), Positives = 92/222 (41%), Gaps = 12/222 (5%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA---N 705 SP+H+A+ GH + + LLLE L G C + + T ML A Sbjct: 793 SPMHWASYTGHEDCLELLLEHSPFSYLE---GNPFTPLHCAVINNQDSTTEMLLGALGAK 849 Query: 706 IHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEV-SDADFDDD 882 I + G T +H AA + LR++L +N T H + + A+ Sbjct: 850 IVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQAE-----VNATDHTGRTALMTAAESGQT 904 Query: 883 GLVKMVNWKADGGLT--------PLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 V+ + ++ LT LH+A GH +C ++L A ++ + + T L Sbjct: 905 AAVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCALMIL---AETQDLGLINATNSAL 961 Query: 1039 LGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 PLH AA G A Q L++RGA + A + G TP + Sbjct: 962 ----QMPLHIAARNGLASVVQALLSRGATVLAVDEEGHTPAL 999 Score = 44.7 bits (104), Expect = 0.002 Identities = 36/95 (37%), Positives = 47/95 (49%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 TPLH AA G V +QLLL GA+V+ T+ L TPLH AA N L Sbjct: 43 TPLHAAAYVGDVPILQLLLMSGANVNAKD-----TLWL-----TPLHRAAASRNEKVLGL 92 Query: 1105 LIARGANLAAKNASGSTPLMVAHSWHRNSIEEILS 1209 L+A A++ A++ TPL VA + E L+ Sbjct: 93 LLAHSADVNARDKLWQTPLHVAAANRATKCAEALA 127 Score = 37.0 bits (84), Expect = 0.33 Identities = 36/130 (27%), Positives = 53/130 (40%), Gaps = 3/130 (2%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE--- 606 L++AA G LL Y + +N+ LH A ++GH + ++L + Sbjct: 895 LMTAAESGQTAAVEFLL-YRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGL 953 Query: 607 INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRL 786 IN N Q L A + G VVQ L+ A + D A+ A A CL L Sbjct: 954 INATNSALQMPLHIAARNGLASVVQALLSRGATVLAVDEEGHTPALACAPNKDVADCLAL 1013 Query: 787 VLADYVPSIP 816 +L+ P P Sbjct: 1014 ILSTMKPFPP 1023
>Q8NB46:ANR52_HUMAN Ankyrin repeat domain-containing protein 52 - Homo sapiens (Human)| Length = 1076 Score = 93.2 bits (230), Expect = 4e-18 Identities = 70/212 (33%), Positives = 97/212 (45%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA G +L+++G EI+ + G T L A +YGH ++ TLM A+ R Sbjct: 308 SPLHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTAR 367 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 ++ +H A L G + C R +L S + S+E V A FD Sbjct: 368 RG-IHDMFPLHLAVLFGFSDCCRKLL-----SSGQLYSIVSSLSNEHVLSAGFD------ 415 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 +N + G T LH AA G+VEC+ LLL GA + G TPLHYAA Sbjct: 416 -INTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRD----------KFGRTPLHYAA 464 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G+ C L+ GA + + G +PL A Sbjct: 465 ANGSYQCAVTLVTAGAGVNEADCKGCSPLHYA 496 Score = 84.7 bits (208), Expect = 1e-15 Identities = 66/233 (28%), Positives = 102/233 (43%), Gaps = 5/233 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA GH E + L E+ V +++R+++G+TAL A + G E V+ L A+ Sbjct: 587 SPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALI 646 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + T +H AA GH L L+ ++ + +V DA Sbjct: 647 KERKRKWTPLHAAAASGHTDSLHLL-----------IDSGERADITDVMDA--------- 686 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 G TPL +A +NGHV+CV LLL+ G++ + G T LH A Sbjct: 687 -------YGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLR----------GRTALHRGA 729 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWH-----RNSIEEILSNEP 1218 G C L+ A + ++ G TP+ +A + R ++ LS +P Sbjct: 730 VTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALSTDP 782 Score = 79.7 bits (195), Expect = 4e-14 Identities = 66/216 (30%), Positives = 103/216 (47%), Gaps = 5/216 (2%) Frame = +1 Query: 538 PLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT 717 PLH+AA GH E++ LL+ G ++ ++ +G L A G EVV+ L+ A I Sbjct: 176 PLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEP 235 Query: 718 DYLNGGTAIHFAALHGH-ARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + G TA+H A G A + LV A + PN T + ++ + LV Sbjct: 236 NAF-GNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVN 294 Query: 895 M---VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS-GSTPL 1062 VN++ G +PLHMAA++G + S++ I++G+ ID G+TPL Sbjct: 295 NGADVNYQVPEGKSPLHMAAIHGRF-----------TRSQILIQNGSEIDCADKFGNTPL 343 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 H AA G+ + L+ GA+ A + PL +A Sbjct: 344 HVAARYGHELLISTLMTNGADTARRGIHDMFPLHLA 379 Score = 79.0 bits (193), Expect = 8e-14 Identities = 72/232 (31%), Positives = 109/232 (46%), Gaps = 6/232 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 S LH+A GH E V+LLL G +N+ + + + L A GH EV++ L+ A++ Sbjct: 142 SALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLGC 201 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVL--ADYVPSIPNFLNQTKHRSSEEVSDA-DFDDDG 885 D G +H AA G ++ +L + F N H + DA + Sbjct: 202 KD-RKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVN 260 Query: 886 LVKMVNWKADGGLTPLHMAAL--NGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTP 1059 VN D G TPLH+AA+ NG + C++LL++ GA V+ E G +P Sbjct: 261 AGANVNQPNDKGFTPLHVAAVSTNGAL-CLELLVNNGADVNYQVPE----------GKSP 309 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW-HRNSIEEILSN 1212 LH AA G Q+LI G+ + + G+TPL VA + H I +++N Sbjct: 310 LHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTN 361 Score = 73.6 bits (179), Expect = 3e-12 Identities = 73/260 (28%), Positives = 112/260 (43%), Gaps = 15/260 (5%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L +AA G ++ + LL + + FG N+ LH A G + L+ +G +N Sbjct: 210 LHTAAASGQIEVVKYLLRMGAEIDEPNAFG--NTALHIACYLGQDAVAIELVNAGANVNQ 267 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL- 792 N +G T L A + + L++ N G + +H AA+HG ++++ Sbjct: 268 PNDKGFTPLHVAAVSTNGALCLELLVNNGADVNYQVPEGKSPLHMAAIHGRFTRSQILIQ 327 Query: 793 -ADYVPSIPNFLNQTKH---RSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHV 960 + F N H R E+ + +G D + PLH+A L G Sbjct: 328 NGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRGIHD--MFPLHLAVLFGFS 385 Query: 961 ECVQLLLDLG---ASVSEVTIE-------DGTTIDLLGSGSTPLHYAACGGNAVCCQLLI 1110 +C + LL G + VS ++ E D T D L G T LH AA GGN C LL+ Sbjct: 386 DCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNL--GRTCLHAAASGGNVECLNLLL 443 Query: 1111 ARGANLAAKNASGSTPLMVA 1170 + GA+L ++ G TPL A Sbjct: 444 SSGADLRRRDKFGRTPLHYA 463 Score = 72.8 bits (177), Expect = 5e-12 Identities = 66/238 (27%), Positives = 104/238 (43%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 LV A D++E R+LL + R +PLH AA G I+ LLL SG +N Sbjct: 12 LVQAIFSRDVEEVRSLLSQKENINVLDQ--ERRTPLHAAAYVGDVPILQLLLMSGANVNA 69 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ T L +A + +V+ L+ +A+++ D L T +H AA + +C + Sbjct: 70 KDTLWLTPLHRAAASRNEKVLGLLLAHSADVNARDKL-WQTPLHVAAANRATKCAEALAP 128 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 L+ +N G + LH A +GH+E V L Sbjct: 129 ------------------------------LLSSLNVADRSGRSALHHAVHSGHLETVNL 158 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 LL+ GAS++ ++ PLH+AA G+ +LL+ARGA+L K+ G Sbjct: 159 LLNKGASLNVCDKKE----------RQPLHWAAFLGHLEVLKLLVARGADLGCKDRKG 206 Score = 60.8 bits (146), Expect = 2e-08 Identities = 51/165 (30%), Positives = 73/165 (44%), Gaps = 1/165 (0%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML-FNANIH 711 +PLH AA + + +LL+ E+N ++ G+TALM A + G V+ L+ A++ Sbjct: 860 TPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRGKADLT 919 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 D N TA+H A GH +C ++L A+ D GL+ Sbjct: 920 VLDE-NKNTALHLACSKGHEKCALMIL------------------------AETQDLGLI 954 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGT 1026 N PLH+AA NG VQ LL GA+V V E T Sbjct: 955 NATNSALQ---MPLHIAARNGLASVVQALLSHGATVLAVDEEGHT 996 Score = 59.7 bits (143), Expect = 5e-08 Identities = 90/379 (23%), Positives = 142/379 (37%), Gaps = 51/379 (13%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH AA+ G+ E ++LLL SG ++ R+ G+T L A G ++ TL+ A ++ D Sbjct: 427 LHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEAD 486 Query: 721 YLNGGTAIHFAALHGHAR----------------------------CLRLVLADYV-PSI 813 G + +H+AA R CL +L + PS+ Sbjct: 487 -CKGCSPLHYAAASDTYRRAEPHTPSSHDAEEDEPLKESRRKEAFFCLEFLLDNGADPSL 545 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLT----PLHMAALNGHVECVQLLL 981 + T + + + L N D T PLH+AA NGH E ++ L Sbjct: 546 RDRQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLA 605 Query: 982 DLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGS-TP 1158 + ++ + + D G T L A G+ C ++L A GA+ K TP Sbjct: 606 E---TLVNLDVRD-------HKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTP 655 Query: 1159 L-MVAHSWHRNSIEEILSNEPGGQIRTLPSPYLCLPLM-SIMSIARECGWRYLNKSPV-- 1326 L A S H +S+ ++ + I + Y PLM +IM+ +C L K Sbjct: 656 LHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTAD 715 Query: 1327 -------------CIDPCAVCLDGSCSVAAEGCKHEFCTRCALYLCSTSYTSANPAGAIP 1467 + C CL A +F R ++L S +A + Sbjct: 716 AADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQ 775 Query: 1468 CPLCRHPIISFVALPGTSP 1524 L P+ + V G SP Sbjct: 776 AALSTDPLDAGVDYSGYSP 794 Score = 44.7 bits (104), Expect = 0.002 Identities = 36/95 (37%), Positives = 47/95 (49%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 TPLH AA G V +QLLL GA+V+ T+ L TPLH AA N L Sbjct: 43 TPLHAAAYVGDVPILQLLLMSGANVNAKD-----TLWL-----TPLHRAAASRNEKVLGL 92 Query: 1105 LIARGANLAAKNASGSTPLMVAHSWHRNSIEEILS 1209 L+A A++ A++ TPL VA + E L+ Sbjct: 93 LLAHSADVNARDKLWQTPLHVAAANRATKCAEALA 127 Score = 38.1 bits (87), Expect = 0.15 Identities = 36/130 (27%), Positives = 54/130 (41%), Gaps = 3/130 (2%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE--- 606 L++AA +G LL Y + +N+ LH A ++GH + ++L + Sbjct: 895 LMTAAENGQTAAVEFLL-YRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGL 953 Query: 607 INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRL 786 IN N Q L A + G VVQ L+ A + D A+ A A CL L Sbjct: 954 INATNSALQMPLHIAARNGLASVVQALLSHGATVLAVDEEGHTPALACAPNKDVADCLAL 1013 Query: 787 VLADYVPSIP 816 +L+ P P Sbjct: 1014 ILSTMKPFPP 1023
>Q6DD51:CSKI2_XENLA Caskin-2 - Xenopus laevis (African clawed frog)| Length = 1205 Score = 92.4 bits (228), Expect = 7e-18 Identities = 70/221 (31%), Positives = 106/221 (47%), Gaps = 2/221 (0%) Frame = +1 Query: 523 GGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 G PLHYAA QG E V LLL + +N ++ GQ L A QYGH+EV +TL+ + Sbjct: 80 GNGMRPLHYAAWQGQPEPVRLLLRASASVNAASHDGQIPLHLAAQYGHYEVSETLLQHQS 139 Query: 703 NIHRTDYLNGG--TAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFD 876 N ++N G T + A G + ++L+L ++ + L T S++ +D +F Sbjct: 140 N---PCHVNKGKKTPLDLACEFGRVKVVQLLLNSHL--CVSLLEGT----SKDPTDPNF- 189 Query: 877 DDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGST 1056 TPLH+AA NGH+E ++LLL LG +++VT T Sbjct: 190 ---------------TTPLHLAAKNGHLEVIRLLLKLGIEINKVT-----------KMGT 223 Query: 1057 PLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW 1179 LH AA G +LLI G ++ +N T L + + + Sbjct: 224 ALHEAALCGKTEVVKLLIENGVDVNIRNTYNQTALDIVNQF 264 Score = 53.5 bits (127), Expect = 3e-06 Identities = 37/103 (35%), Positives = 54/103 (52%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 VN + G + LH AAL+G+ E + LLL++ ASV I+DG +G PLHYAA Sbjct: 42 VNHQDADGFSALHHAALSGNSELLLLLLEMQASVD---IKDG-------NGMRPLHYAAW 91 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 G +LL+ A++ A + G PL +A + + E L Sbjct: 92 QGQPEPVRLLLRASASVNAASHDGQIPLHLAAQYGHYEVSETL 134 Score = 49.3 bits (116), Expect = 6e-05 Identities = 46/170 (27%), Positives = 74/170 (43%) Frame = +1 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 N++ D +G +A+H AAL G++ L L+L + ++S ++ D + Sbjct: 41 NVNHQD-ADGFSALHHAALSGNSELLLLLL--------------EMQASVDIKDGN---- 81 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 G+ PLH AA G E V+LLL ASV+ + + G PL Sbjct: 82 ------------GMRPLHYAAWQGQPEPVRLLLRASASVNAASHD----------GQIPL 119 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSN 1212 H AA G+ + L+ +N N TPL +A + R + ++L N Sbjct: 120 HLAAQYGHYEVSETLLQHQSNPCHVNKGKKTPLDLACEFGRVKVVQLLLN 169
>Q9H2K2:TNKS2_HUMAN Tankyrase-2 - Homo sapiens (Human)| Length = 1166 Score = 91.7 bits (226), Expect = 1e-17 Identities = 86/305 (28%), Positives = 128/305 (41%), Gaps = 51/305 (16%) Frame = +1 Query: 400 GNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIV 579 G S G S + +L+ AA+ GD++ + L R G +++PLH+AA +V Sbjct: 484 GISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCR-DIEGRQSTPLHFAAGYNRVSVV 542 Query: 580 SLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAAL 759 LL+ G +++ ++ G L AC YGH+EV + L+ A ++ D L T +H AA Sbjct: 543 EYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVAD-LWKFTPLHEAAA 601 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK--------------- 894 G +L+L + P N+ + + V D D D L++ Sbjct: 602 KGKYEICKLLLQH--GADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLA 659 Query: 895 ---------MVNWKADGG--LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 VN + G TPLH+AA ++E + LL GA V+ + G I L Sbjct: 660 RVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVN--AQDKGGLIPLH 717 Query: 1042 GSGS-------------------------TPLHYAACGGNAVCCQLLIARGANLAAKNAS 1146 + S TPLH AA G C LL+A GA+ KN Sbjct: 718 NAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQE 777 Query: 1147 GSTPL 1161 G TPL Sbjct: 778 GQTPL 782 Score = 90.5 bits (223), Expect = 3e-17 Identities = 85/285 (29%), Positives = 128/285 (44%), Gaps = 24/285 (8%) Frame = +1 Query: 424 SGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGV 603 + L A R+GD++ + L+ +R T G +++PLH+AA G ++V LL++G Sbjct: 24 AARELFEACRNGDVERVKRLVTPEKVNSR-DTAGRKSTPLHFAAGFGRKDVVEYLLQNGA 82 Query: 604 EINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR-CL 780 + R+ G L AC +GH EVV L+ A+ + D N T +H AA+ G C+ Sbjct: 83 NVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWN-YTPLHEAAIKGKIDVCI 141 Query: 781 RLVLADYVPSIPNFLNQT----KHRSSEEVSDADFDDDGLVKM----------------- 897 L+ P+I N +T S++ V ++ D L++ Sbjct: 142 VLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLN 201 Query: 898 VNWKADGG--LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYA 1071 VN A G TPLH+AA V+ VQLLL GA V D PLH A Sbjct: 202 VNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGD----------LVPLHNA 251 Query: 1072 ACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 G+ +LL+ GA + A + TPL A S +R + +L Sbjct: 252 CSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 296 Score = 67.0 bits (162), Expect = 3e-10 Identities = 63/239 (26%), Positives = 107/239 (44%), Gaps = 30/239 (12%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH A+ + H+++V ++++ ++N + GQT+L +A GH + + L+ + + + Sbjct: 402 TPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNI 461 Query: 715 TDYLNGGTAIHFAALH-----------GHARCLRLVL----ADYVPSIP--------NFL 825 L G TA+ + G++ R +L A V ++ N Sbjct: 462 IS-LQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCR 520 Query: 826 NQTKHRSSEEVSDADFDDDGLVKM-------VNWKADGGLTPLHMAALNGHVECVQLLLD 984 + +S+ A ++ +V+ V+ K GGL PLH A GH E +LL+ Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVK 580 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL 1161 GA V+ + TPLH AA G C+LL+ GA+ KN G+TPL Sbjct: 581 HGAVVNVADLWK----------FTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPL 629 Score = 56.2 bits (134), Expect = 5e-07 Identities = 72/304 (23%), Positives = 112/304 (36%), Gaps = 80/304 (26%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL--------------------MQAC 654 +PLH AA +G ++ +LL+ G E +RN G+TAL +++ Sbjct: 126 TPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESA 185 Query: 655 QYGHWEVVQTLML-FNANIHRTDYLNGGTAIHFAALHGHARCLRLVL-----------AD 798 + G+ E + L+ N N H +D T +H AA + + ++L+L D Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKS-TPLHLAAGYNRVKIVQLLLQHGADVHAKDKGD 244 Query: 799 YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVN-WKADGGLTPLHMAALNGHVECVQL 975 VP L+ EV++ V ++ W+ TPLH AA VE L Sbjct: 245 LVP-----LHNACSYGHYEVTELLVKHGACVNAMDLWQ----FTPLHEAASKNRVEVCSL 295 Query: 976 LLDLGASVSEVTIEDGTTIDLL-------------------------------------- 1041 LL GA + + + + IDL Sbjct: 296 LLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEM 355 Query: 1042 ------GSGSTPLHYAACG---GNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSI 1194 + T LH AA C+LL+ +GAN+ K TPL VA N + Sbjct: 356 VNFKHPQTHETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDV 415 Query: 1195 EEIL 1206 E++ Sbjct: 416 VEVV 419 Score = 49.7 bits (117), Expect = 5e-05 Identities = 63/253 (24%), Positives = 104/253 (41%), Gaps = 29/253 (11%) Frame = +1 Query: 538 PLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA----- 702 PLH A + GH+E+ LL++ G +N + T L +A EV L+ + A Sbjct: 247 PLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLL 306 Query: 703 NIHR--------TDYLNGGTAIHFAALHGHARCLRLVLADYVP-------SIPNFLNQTK 837 N H T L A F GH+ AD + NF + Sbjct: 307 NCHNKSAIDLAPTPQLKERLAYEFK---GHSLLQAAREADVTRIKKHLSLEMVNFKHPQT 363 Query: 838 HRSSEEVSDADFDD------DGLVKM---VNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 H ++ + A + L++ +N K LTPLH+A+ H + V++++ Sbjct: 364 HETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHE 423 Query: 991 ASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 A V+ +D L G T LH AA G+ C+LL++ G + + G T L + Sbjct: 424 AKVN--------ALDNL--GQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMG 473 Query: 1171 HSWHRNSIEEILS 1209 + + ++E +S Sbjct: 474 NENVQQLLQEGIS 486 Score = 44.3 bits (103), Expect = 0.002 Identities = 69/305 (22%), Positives = 109/305 (35%), Gaps = 81/305 (26%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRN----------------------YRGQTALMQ 648 +PLH AA++ E+ SLLL G + L N ++G + L Sbjct: 279 TPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQA 338 Query: 649 ACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR----CLRLVL--ADYVPS 810 A + + + L L N TA+H AA + + C L+ A+ Sbjct: 339 AREADVTRIKKHLSLEMVNFKHPQ--THETALHCAAASPYPKRKQICELLLRKGANINEK 396 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVK---MVNWKADGGLTPLHMAALNGHVECVQLLL 981 FL S + +D + +VK VN + G T LH AA GH++ +LLL Sbjct: 397 TKEFLTPLHVASEKAHNDVV---EVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLL 453 Query: 982 DLGASVSEVTIEDGTTI------------------------------------------- 1032 G + ++++ T + Sbjct: 454 SYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCT 513 Query: 1033 -------DLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS 1191 D+ G STPLH+AA + L+ GA++ AK+ G PL A S+ Sbjct: 514 VQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYE 573 Query: 1192 IEEIL 1206 + E+L Sbjct: 574 VAELL 578
>Q07DZ5:CTTB2_ORNAN Cortactin-binding protein 2 - Ornithorhynchus anatinus (Duckbill| platypus) Length = 1635 Score = 91.3 bits (225), Expect = 1e-17 Identities = 70/216 (32%), Positives = 103/216 (47%), Gaps = 5/216 (2%) Frame = +1 Query: 517 TFGGRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLML 693 + GGR + LH AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ Sbjct: 694 SLGGRPTRLHQAAAQGNVTLLSVLLNEEGLDINHACEDGSSALYSAAKNGHTDCVRLLLN 753 Query: 694 FNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADF 873 NA + D NG T + AA GH +C L++A + Sbjct: 754 ANAQVDDAD-KNGFTPLCSAAAQGHVKCAELLIAYHAD---------------------- 790 Query: 874 DDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS 1053 +N A+GG TPL++A NG+ EC++LLL+ G S +T DG Sbjct: 791 --------INHAAEGGQTPLYLACKNGNNECIKLLLEAGTDRS-ITTSDGW--------- 832 Query: 1054 TPLHYAACGGNAVCCQLLIARGA----NLAAKNASG 1149 TP+H A GN LL+ G N +K+ +G Sbjct: 833 TPVHAAVDSGNVDSLTLLMYYGGPESENSGSKDQTG 868 Score = 57.8 bits (138), Expect = 2e-07 Identities = 61/205 (29%), Positives = 88/205 (42%), Gaps = 8/205 (3%) Frame = +1 Query: 415 CSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLE 594 C L SAA++G R LL N ++ G +PL AAAQGH + LL+ Sbjct: 729 CEDGSSALYSAAKNGHTDCVRLLLNANAQVDDADKNGF--TPLCSAAAQGHVKCAELLIA 786 Query: 595 SGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR 774 +IN GQT L AC+ G+ E ++ L+ + T +G T +H A G+ Sbjct: 787 YHADINHAAEGGQTPLYLACKNGNNECIKLLLEAGTDRSITTS-DGWTPVHAAVDSGNVD 845 Query: 775 CLRLVLADYVPSIPNF--LNQTKHRSSEE------VSDADFDDDGLVKMVNWKADGGLTP 930 L L++ P N +QT S EE V AD ++N G T Sbjct: 846 SLTLLMYYGGPESENSGSKDQTGLGSREESRGAMPVISAD--------LINQADKEGWTA 897 Query: 931 LHMAALNGHVECVQLLLDLGASVSE 1005 H+AA G C+++L G +E Sbjct: 898 AHIAASKGLKNCLEILCGHGRLEAE 922 Score = 56.6 bits (135), Expect = 4e-07 Identities = 39/119 (32%), Positives = 59/119 (49%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L+Q + + + +++GL +N + G + L+ AA NGH +CV+LLL+ A Sbjct: 699 PTRLHQAAAQGNVTLLSVLLNEEGLD--INHACEDGSSALYSAAKNGHTDCVRLLLNANA 756 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 V D +G TPL AA G+ C +LLIA A++ G TPL +A Sbjct: 757 QVD----------DADKNGFTPLCSAAAQGHVKCAELLIAYHADINHAAEGGQTPLYLA 805 Score = 54.7 bits (130), Expect = 2e-06 Identities = 60/249 (24%), Positives = 103/249 (41%), Gaps = 20/249 (8%) Frame = +1 Query: 433 RLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEIN 612 RL AA G++ LL ++ G +S L+ AA GH + V LLL + +++ Sbjct: 701 RLHQAAAQGNVTLLSVLLNEEGLDINHACEDG-SSALYSAAKNGHTDCVRLLLNANAQVD 759 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH + + L+ ++A+I+ G T ++ A +G+ C++L+L Sbjct: 760 DADKNGFTPLCSAAAQGHVKCAELLIAYHADINHAAE-GGQTPLYLACKNGNNECIKLLL 818 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + + ++ +D G TP+H A +G+V+ + Sbjct: 819 --------------EAGTDRSITTSD----------------GWTPVHAAVDSGNVDSLT 848 Query: 973 LLLDLGASVSEVT-IEDGT---------------TIDLLG----SGSTPLHYAACGGNAV 1092 LL+ G SE + +D T + DL+ G T H AA G Sbjct: 849 LLMYYGGPESENSGSKDQTGLGSREESRGAMPVISADLINQADKEGWTAAHIAASKGLKN 908 Query: 1093 CCQLLIARG 1119 C ++L G Sbjct: 909 CLEILCGHG 917
>O95271:TNKS1_HUMAN Tankyrase-1 - Homo sapiens (Human)| Length = 1327 Score = 89.0 bits (219), Expect = 7e-17 Identities = 83/297 (27%), Positives = 125/297 (42%), Gaps = 51/297 (17%) Frame = +1 Query: 433 RLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEIN 612 RL+ A++ GDL+ + L R G ++PLH+AA +V LL G +++ Sbjct: 653 RLLEASKAGDLETVKQLCSSQNVNCR-DLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVH 711 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 ++ G L AC YGH+EV + L+ A+++ D L T +H AA G +L+L Sbjct: 712 AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVAD-LWKFTPLHEAAAKGKYEICKLLL 770 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK------------------------MV 900 + P N+ + + V + D D L+K + Sbjct: 771 KH--GADPTKKNRDGNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENI 828 Query: 901 NWKADGG--LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS------- 1053 N + G TPLH+AA ++E + LL+ GA V+ + G I L + S Sbjct: 829 NCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVN--AQDKGGLIPLHNAASYGHVDIA 886 Query: 1054 ------------------TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 TPLH AA G C LL+A GA+ KN G TPL +A Sbjct: 887 ALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 943 Score = 87.0 bits (214), Expect = 3e-16 Identities = 83/298 (27%), Positives = 131/298 (43%), Gaps = 47/298 (15%) Frame = +1 Query: 418 SASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLES 597 S + L+ A R+GD+ + L++ A+ G ++SPLH+AA G ++V LL+ Sbjct: 180 SGALRELLEACRNGDVSRVKRLVDAANVNAK-DMAGRKSSPLHFAAGFGRKDVVEHLLQM 238 Query: 598 GVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR- 774 G ++ R+ G L AC +GH EVV L+ A+ + D N T +H AA+ G Sbjct: 239 GANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWN-YTPLHEAAIKGKIDV 297 Query: 775 CLRLVLADYVPSIPNFLNQT----KHRSSEEVSDADFDDDGLVKM--------------- 897 C+ L+ P+I N ++ S++ V ++ D L++ Sbjct: 298 CIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTP 357 Query: 898 --VNWKADGG--LTPLHMAALNGHVECVQLLLDLGA----------------------SV 999 VN A G TPLH+AA V VQLLL GA V Sbjct: 358 LNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEV 417 Query: 1000 SEVTIEDGTTIDLLGSGS-TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 +E+ ++ G ++ + TPLH AA C LL++ GA+ N G + + +A Sbjct: 418 TELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 475 Score = 73.6 bits (179), Expect = 3e-12 Identities = 82/327 (25%), Positives = 142/327 (43%), Gaps = 50/327 (15%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 + L+ AAR G+ ++ ALL + +++ G +++PLH AA IV LLL+ G ++ Sbjct: 337 DELLEAARSGNEEKLMALLT-PLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADV 395 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 + ++ G L AC YGH+EV + L+ A ++ D L T +H AA L+ Sbjct: 396 HAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD-LWQFTPLHEAASKNRVEVCSLL 454 Query: 790 LADYV-PSIPN----------------------FLNQTKHRSSEEVSDADFDDDGLVKMV 900 L+ P++ N F + +++ E A ++++ Sbjct: 455 LSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEII 514 Query: 901 NWK-ADGGLTPLHMAALNGH---VECVQLLLDLGASVS---------------------- 1002 N+K T LH A + H + +LLL GA+V+ Sbjct: 515 NFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVM 574 Query: 1003 EVTIEDGTTIDLLGS-GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW 1179 EV + G ++ L + G T LH AA G+ C+LL++ G++ + + G T + + Sbjct: 575 EVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGN-- 632 Query: 1180 HRNSIEEILSNEPGGQIRTLPSPYLCL 1260 ++++ILS IRT Y L Sbjct: 633 --EAVQQILSEST--PIRTSDVDYRLL 655 Score = 39.7 bits (91), Expect = 0.051 Identities = 32/97 (32%), Positives = 47/97 (48%) Frame = +1 Query: 916 GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVC 1095 G L L A NG V V+ L+D A+V+ D+ G S+PLH+AA G Sbjct: 181 GALRELLEACRNGDVSRVKRLVD-AANVNAK--------DMAGRKSSPLHFAAGFGRKDV 231 Query: 1096 CQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 + L+ GAN+ A++ G PL A S+ + +L Sbjct: 232 VEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLL 268
>O89019:INVS_MOUSE Inversin - Mus musculus (Mouse)| Length = 1062 Score = 88.2 bits (217), Expect = 1e-16 Identities = 86/290 (29%), Positives = 135/290 (46%), Gaps = 37/290 (12%) Frame = +1 Query: 475 RALLEYNPR--LARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRG--QTAL 642 R +L+ P L + + GR +PLH+A A G+ +V +L S N+ +Y +T L Sbjct: 202 RCILDAAPTESLLNWQDYEGR-TPLHFAVADGNLTVVDVLT-SYESCNITSYDNLFRTPL 259 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNF 822 A GH ++V L+ N + G T +H+AA A +++ L PS+ + Sbjct: 260 HWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLQH--PSVKDD 317 Query: 823 LNQTKHRSSEEVSDADFDDDGLVKMVNWKAD---------GGLTPLHMAALNGHVECVQL 975 + + R+S + +DD L M++ K+D GG T LH AAL+GHV V+L Sbjct: 318 -SDLEGRTSFMWAAGKGNDDVLRTMLSLKSDIDINMSDKYGG-TALHAAALSGHVSTVKL 375 Query: 976 LLDLGASVS----------------------EVTIEDGTTIDLLGS-GSTPLHYAACGGN 1086 LLD A V + I+ G +DL+ G + LH+AA GGN Sbjct: 376 LLDNDAQVDATDVMKHTPLFRACEMGHRDVIQTLIKGGARVDLVDQDGHSLLHWAALGGN 435 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLM-VAHSWHRNSIEEILSNEPGGQIR 1233 A CQ+LI N ++ +G TPL A+ + N + ++ N I+ Sbjct: 436 ADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQ 485 Score = 75.5 bits (184), Expect = 8e-13 Identities = 58/208 (27%), Positives = 105/208 (50%), Gaps = 7/208 (3%) Frame = +1 Query: 520 FGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 +GG + LH AA GH V LLL++ +++ + T L +AC+ GH +V+QTL+ Sbjct: 356 YGG--TALHAAALSGHVSTVKLLLDNDAQVDATDVMKHTPLFRACEMGHRDVIQTLIKGG 413 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV-PSIPNFLNQTKHRSSEEVSDADFD 876 A + D +G + +H+AAL G+A ++++ + + P++ ++ +T + + + + Sbjct: 414 ARVDLVDQ-DGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA---AYGGYI 469 Query: 877 DDGLVKMVNWKAD------GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 + V M N AD G T LH + NG+++ ++LLLD A +++ + Sbjct: 470 NCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNE------ 522 Query: 1039 LGSGSTPLHYAACGGNAVCCQLLIARGA 1122 TPL YA G Q ++ GA Sbjct: 523 --ERYTPLDYALLGERHEVIQFMLEHGA 548 Score = 64.7 bits (156), Expect = 1e-09 Identities = 75/296 (25%), Positives = 122/296 (41%), Gaps = 45/296 (15%) Frame = +1 Query: 418 SASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLES 597 S+ ++ +AA +GD + L+ N L GR +PL Y + LL++ Sbjct: 12 SSLASQVHAAAVNGDKGALQRLIVGNSALRDKEDRFGR-TPLMYCVLADRVDCADALLKA 70 Query: 598 GVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARC 777 G ++N ++ +TAL A Q G++ ++ L+ AN + D L T +H + H +C Sbjct: 71 GADVNKTDHSRRTALHLAAQKGNYRFMKLLLTRRANWMQKD-LEEMTPLHLSTRHRSPKC 129 Query: 778 LRLVLADYVPSIPNFLNQT---------------------KHRSSEEVSD---------- 864 L L+L P + ++ KH S+ + D Sbjct: 130 LALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHAKLLIKHDSNIGIPDVEGKIPLHWA 189 Query: 865 ADFDDDGLV-------------KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSE 1005 A+ D V ++NW+ G TPLH A +G++ V +L S Sbjct: 190 ANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNLTVVDVL----TSYES 245 Query: 1006 VTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG-ANLAAKNASGSTPLMVA 1170 I T+ D L TPLH+AA G+A LL+ R + ++ G+TPL A Sbjct: 246 CNI---TSYDNL--FRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
>P23631:LATA_LATMA Alpha-latrotoxin precursor - Latrodectus mactans (Black widow spider)| Length = 1401 Score = 87.8 bits (216), Expect = 2e-16 Identities = 71/234 (30%), Positives = 111/234 (47%), Gaps = 8/234 (3%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLM-LFNANIH 711 +PLHYA G + + L + +++N ++ G T A W V TL+ +I+ Sbjct: 596 TPLHYAIRGGERILEAFLNQISIDVNAKSNTGLTPFHLAIIKNDWPVASTLLGSKKVDIN 655 Query: 712 RTDYLNGGTAIHFAALHGHARC------LRLVLADYVPSIPNFLNQTKHRSSEEVSD-AD 870 D N TA+H+AA+ G+ L+ + A+ V S P L+ + + D A Sbjct: 656 AVDE-NNITALHYAAILGYLETTKQLINLKEINANVVSS-PGLLSALHYAILYKHDDVAS 713 Query: 871 FDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSG 1050 F VN KA GG+TPLH+A + G + + L+ D+G ++ + T E Sbjct: 714 FLMRSSNVNVNLKALGGITPLHLAVIQGRKQILSLMFDIGVNIEQKTDEK---------- 763 Query: 1051 STPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSN 1212 TPLH AA Q+L+ +G+N AK SG+TPL +A ++ IL N Sbjct: 764 YTPLHLAAMSKYPELIQILLDQGSNFEAKTNSGATPLHLATFKGKSQAALILLN 817 Score = 68.2 bits (165), Expect = 1e-10 Identities = 66/256 (25%), Positives = 116/256 (45%), Gaps = 17/256 (6%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G L A+A++ + + ++PL+ AA H +++ ++ G +IN RN Sbjct: 836 AAMTGLLDVAQAIISIDATVVDIEDKNS-DTPLNLAAQNSHIDVIKYFIDQGADINTRNK 894 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 +G L+ + G+ ++V+ L NAN++ D +G ++A +GH ++ +++ Sbjct: 895 KGLAPLLAFSKKGNLDMVKYLFDKNANVYIADN-DGMNFFYYAVQNGHLNIVKYAMSE-- 951 Query: 805 PSIPNFLNQTKHRSSE-----------EVSDA-DFDDDGLVK-----MVNWKADGGLTPL 933 + N +R E V DA FD +VK + N+ G PL Sbjct: 952 KDKFEWSNTDNNRRDECPNEECAISHFAVCDAVQFDRIEIVKYFVGTLGNFAICG---PL 1008 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA 1113 H AA GH++ V+ L++ E DG+ D TPL YA+ G+ Q L++ Sbjct: 1009 HQAARYGHLDIVKYLVE-----EEFLSVDGSKTD------TPLCYASENGHFTVVQYLVS 1057 Query: 1114 RGANLAAKNASGSTPL 1161 GA + +G T + Sbjct: 1058 NGAKVNHDCGNGMTAI 1073 Score = 64.7 bits (156), Expect = 1e-09 Identities = 55/213 (25%), Positives = 94/213 (44%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN 705 G +PLH A QG +I+SL+ + GV I + T L A + E++Q L+ +N Sbjct: 729 GGITPLHLAVIQGRKQILSLMFDIGVNIEQKTDEKYTPLHLAAMSKYPELIQILLDQGSN 788 Query: 706 IHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG 885 +G T +H A G ++ ++L + EV+ D D++G Sbjct: 789 FEAKTN-SGATPLHLATFKGKSQAALILL------------------NNEVNWRDTDENG 829 Query: 886 LVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLH 1065 + P+H AA+ G ++ Q ++ + A+V V IED + TPL+ Sbjct: 830 QM------------PIHGAAMTGLLDVAQAIISIDATV--VDIEDKNS-------DTPLN 868 Query: 1066 YAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 AA + + I +GA++ +N G PL+ Sbjct: 869 LAAQNSHIDVIKYFIDQGADINTRNKKGLAPLL 901 Score = 50.4 bits (119), Expect = 3e-05 Identities = 55/219 (25%), Positives = 94/219 (42%), Gaps = 1/219 (0%) Frame = +1 Query: 385 FLSLVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGR-NSPLHYAAAQ 561 F+ +GN C L AAR G L + L+E S G + ++PL YA+ Sbjct: 995 FVGTLGNFAICGP----LHQAARYGHLDIVKYLVEEE----FLSVDGSKTDTPLCYASEN 1046 Query: 562 GHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTA 741 GH +V L+ +G ++N G TA+ +A H +VVQ L + R + + GT Sbjct: 1047 GHFTVVQYLVSNGAKVNHDCGNGMTAIDKAITKNHLQVVQFLAANGVDFRRKN--SRGTT 1104 Query: 742 IHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGG 921 A+ +A L +A+Y+ + R +++ + D D Sbjct: 1105 PFLTAVAENA----LHIAEYL--------IREKRQDININEQNVDKD------------- 1139 Query: 922 LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 T LH+A +++ ++LL+ G V+ D T +D+ Sbjct: 1140 -TALHLAVYYKNLQMIKLLIKYGIDVTIRNAYDKTALDI 1177 Score = 40.8 bits (94), Expect = 0.023 Identities = 50/166 (30%), Positives = 72/166 (43%), Gaps = 9/166 (5%) Frame = +1 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVS-DADFD 876 ANI T + +G T H AA G+ + + L S LNQ + + AD Sbjct: 482 ANIRAT-FDHGRTVFHAAAKSGNDKIM-FGLTFLAKSTE--LNQPDKKGYTPIHVAADSG 537 Query: 877 DDGLVKM-------VNWKADGGL-TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTI 1032 + G+V + +N K L TPLH+AA G V Q L++ E+ I + Sbjct: 538 NAGIVNLLIQRGVSINSKTYHFLQTPLHLAAQRGFVTTFQRLMES----PEININERDK- 592 Query: 1033 DLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G TPLHYA GG + L ++ AK+ +G TP +A Sbjct: 593 ----DGFTPLHYAIRGGERILEAFLNQISIDVNAKSNTGLTPFHLA 634
>Q09YI1:CTTB2_SHEEP Cortactin-binding protein 2 - Ovis aries (Sheep)| Length = 1641 Score = 87.8 bits (216), Expect = 2e-16 Identities = 67/200 (33%), Positives = 98/200 (49%), Gaps = 1/200 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 702 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 761 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH +C+ L++A DA+ Sbjct: 762 QVNAADK-NGFTPLCAAAAQGHFKCVELLIA---------------------YDAN---- 795 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G S T + G TP+ Sbjct: 796 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRD----------GWTPI 840 Query: 1063 HYAACGGNAVCCQLLIARGA 1122 H A GN +LL+ GA Sbjct: 841 HAAVDTGNVDSLKLLMYHGA 860 Score = 63.2 bits (152), Expect = 4e-09 Identities = 68/254 (26%), Positives = 104/254 (40%), Gaps = 26/254 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 707 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLNAEAQVNA 765 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH++ V+ L+ ++ANI H D G T ++ A +G+ C++L+L Sbjct: 766 ADKNGFTPLCAAAAQGHFKCVELLIAYDANINHAAD--GGQTPLYLACKNGNKECIKLLL 823 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G TP+H A G+V+ ++ Sbjct: 824 ----------------------------EAGTDRSV--KTRDGWTPIHAAVDTGNVDSLK 853 Query: 973 LLLDLGASV--SEVTIEDGTTI-------------------DLL----GSGSTPLHYAAC 1077 LL+ GA +++ E G I DL+ G T H AA Sbjct: 854 LLMYHGAPAHGNKLQEEPGLAIFDLDQEEHHEGTSKPVVPADLINHADSEGWTAAHIAAS 913 Query: 1078 GGNAVCCQLLIARG 1119 G C ++L G Sbjct: 914 KGFKNCLEVLCRHG 927 Score = 62.4 bits (150), Expect = 7e-09 Identities = 57/198 (28%), Positives = 90/198 (45%), Gaps = 7/198 (3%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH + V L Sbjct: 731 NYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGF--TPLCAAAAQGHFKCVEL 788 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT-DYLNGGTAIHFAALH 762 L+ IN GQT L AC+ G+ E ++ +L A R+ +G T IH A Sbjct: 789 LIAYDANINHAADGGQTPLYLACKNGNKECIK--LLLEAGTDRSVKTRDGWTPIHAAVDT 846 Query: 763 GHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK------MVNWKADGGL 924 G+ L+L++ P+ N L + + ++ D + +G K ++N G Sbjct: 847 GNVDSLKLLMYHGAPAHGNKLQEEPGLAIFDL-DQEEHHEGTSKPVVPADLINHADSEGW 905 Query: 925 TPLHMAALNGHVECVQLL 978 T H+AA G C+++L Sbjct: 906 TAAHIAASKGFKNCLEVL 923 Score = 57.8 bits (138), Expect = 2e-07 Identities = 39/119 (32%), Positives = 59/119 (49%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL+ A Sbjct: 704 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 761 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 V+ +G TPL AA G+ C +LLIA AN+ G TPL +A Sbjct: 762 QVNAAD----------KNGFTPLCAAAAQGHFKCVELLIAYDANINHAADGGQTPLYLA 810
>Q12955:ANK3_HUMAN Ankyrin-3 - Homo sapiens (Human)| Length = 4377 Score = 87.4 bits (215), Expect = 2e-16 Identities = 77/272 (28%), Positives = 126/272 (46%), Gaps = 8/272 (2%) Frame = +1 Query: 415 CSASG-ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 C+ +G L A+++G ++ LL+ + + G N+ LH A+ G E+V +L+ Sbjct: 70 CNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG--NTALHIASLAGQAEVVKVLV 127 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 +G +N ++ G T L A Q H EVV+ +L N +G T + A GH Sbjct: 128 TNGANVNAQSQNGFTPLYMAAQENHLEVVK-FLLDNGASQSLATEDGFTPLAVALQQGHD 186 Query: 772 RCLRLVLAD------YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 + + L+L + +P++ + +++ + D + D ++ G TPL Sbjct: 187 QVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNAD-------VESKSGFTPL 239 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA 1113 H+AA G++ LLL+ A+V D TPLH A+ GNA +LL+ Sbjct: 240 HIAAHYGNINVATLLLNRAAAVDFTARND----------ITPLHVASKRGNANMVKLLLD 289 Query: 1114 RGANLAAKNASGSTPLMV-AHSWHRNSIEEIL 1206 RGA + AK G TPL A S H +E +L Sbjct: 290 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLL 321 Score = 83.6 bits (205), Expect = 3e-15 Identities = 72/227 (31%), Positives = 98/227 (43%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +P+H AA GH IVS L+ G N N RG+TAL A + G EVV+ L+ A + Sbjct: 435 TPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV-E 493 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + T +H +A RL AD V + L Q ++ S Sbjct: 494 AKAKDDQTPLHISA--------RLGKADIVQQL---LQQGASPNAATTS----------- 531 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 G TPLH++A GH + LLD GAS+S T G TPLH AA Sbjct: 532 --------GYTPLHLSAREGHEDVAAFLLDHGASLSITT----------KKGFTPLHVAA 573 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNE 1215 G LL+ + A+ A SG TPL VA + + +L ++ Sbjct: 574 KYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 620 Score = 82.8 bits (203), Expect = 5e-15 Identities = 70/250 (28%), Positives = 109/250 (43%), Gaps = 8/250 (3%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A++ G+ + LL+ ++ + G +PLH A GH ++V +LL+ I + Sbjct: 275 ASKRGNANMVKLLLDRGAKIDAKTRDG--LTPLHCGARSGHEQVVEMLLDRAAPILSKTK 332 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIH--RTDYLNGGTAIHFAALHGHARCLRLVLAD 798 G + L A Q H VQ L+ N + DYL TA+H AA GH + +++L Sbjct: 333 NGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYL---TALHVAAHCGHYKVAKVLLDK 389 Query: 799 YVPSIPNFLNQTK------HRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHV 960 LN ++ +V + ++ V + GLTP+H+AA GHV Sbjct: 390 KANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVT---ESGLTPIHVAAFMGHV 446 Query: 961 ECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKN 1140 V L+ GAS + + G T LH AA G A + L+ GA + AK Sbjct: 447 NIVSQLMHHGASPNTTNVR----------GETALHMAARSGQAEVVRYLVQDGAQVEAKA 496 Query: 1141 ASGSTPLMVA 1170 TPL ++ Sbjct: 497 KDDQTPLHIS 506 Score = 82.4 bits (202), Expect = 7e-15 Identities = 83/295 (28%), Positives = 125/295 (42%), Gaps = 14/295 (4%) Frame = +1 Query: 373 ASMGFLSLVGNSFGCSAS-------GER-LVSAARDGDLQEARALLEYNPRLARYSTFGG 528 A MG +++V AS GE L AAR G + R L++ ++ + Sbjct: 441 AFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAK--D 498 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 +PLH +A G +IV LL+ G N G T L + + GH +V L+ A++ Sbjct: 499 DQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASL 558 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVP------SIPNFLNQTKHRSSEEVSDAD 870 T G T +H AA +G L+L S L+ H +++V+ Sbjct: 559 SITTK-KGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLL 617 Query: 871 FDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSG 1050 D A G TPLH+AA ++ LL+ GA + VT + G Sbjct: 618 LDQGASPHAA---AKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQ----------G 664 Query: 1051 STPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNE 1215 +H AA G+ LL+ R AN+ N SG TPL +A R ++ E+L N+ Sbjct: 665 IASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQ 719 Score = 81.6 bits (200), Expect = 1e-14 Identities = 74/241 (30%), Positives = 104/241 (43%), Gaps = 20/241 (8%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA GH E +++GV+IN+ N G AL A + GH EVV L+ AN+ Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAAT-KK 106 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 G TA+H A+L G A ++++ + N N VN + Sbjct: 107 GNTALHIASLAGQAEVVKVL-------VTNGAN-----------------------VNAQ 136 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTT-------------IDLLGSG 1050 + G TPL+MAA H+E V+ LLD GAS S T EDG T + LL Sbjct: 137 SQNGFTPLYMAAQENHLEVVKFLLDNGASQSLAT-EDGFTPLAVALQQGHDQVVSLLLEN 195 Query: 1051 ST-------PLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILS 1209 T LH AA + LL+ N ++ SG TPL +A + ++ +L Sbjct: 196 DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLL 255 Query: 1210 N 1212 N Sbjct: 256 N 256 Score = 77.4 bits (189), Expect = 2e-13 Identities = 76/286 (26%), Positives = 124/286 (43%), Gaps = 30/286 (10%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 +AR G + LL+ +T G +PLH +A +GH ++ + LL+ G +++ Sbjct: 506 SARLGKADIVQQLLQQGASPNAATTSG--YTPLHLSAREGHEDVAAFLLDHGASLSITTK 563 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 +G T L A +YG EV L+ +A+ +G T +H AA + + + + L+L D Sbjct: 564 KGFTPLHVAAKYGKLEVANLLLQKSASPDAAGK-SGLTPLHVAAHYDNQK-VALLLLDQG 621 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADG------GLTPLHMAALNGHVEC 966 S P+ + + + ++ D ++ + AD G+ +H+AA GHV+ Sbjct: 622 AS-PHAAAKNGY-TPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDM 679 Query: 967 VQLLLDLGASVS----------------------EVTIEDGTTIDLLGS-GSTPLHYAAC 1077 V LLL A+V+ EV + G +D G TPLH Sbjct: 680 VSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCH 739 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILSN 1212 GN L+ A + AK +G TPL A H + I +L N Sbjct: 740 YGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQN 785 Score = 75.1 bits (183), Expect = 1e-12 Identities = 73/254 (28%), Positives = 109/254 (42%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AAR D + A LL+ + S G +PLH AA G+ + +LLL ++ Sbjct: 209 AARKDDTKAAALLLQNDNNADVESKSGF--TPLHIAAHYGNINVATLLLNRAAAVDFTAR 266 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 T L A + G+ +V+ L+ A I +G T +H A GH + + ++L Sbjct: 267 NDITPLHVASKRGNANMVKLLLDRGAKIDAKTR-DGLTPLHCGARSGHEQVVEMLLDRAA 325 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 P L++TK+ GL+PLHMA H+ CVQLLL Sbjct: 326 P----ILSKTKN--------------------------GLSPLHMATQGDHLNCVQLLLQ 355 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 V +VT T LH AA G+ ++L+ + AN AK +G TPL Sbjct: 356 HNVPVDDVT----------NDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLH 405 Query: 1165 VAHSWHRNSIEEIL 1206 +A +R + E+L Sbjct: 406 IACKKNRIKVMELL 419 Score = 68.6 bits (166), Expect = 1e-10 Identities = 57/198 (28%), Positives = 83/198 (41%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA+ + A LLEY + G + +H AA +GH ++VSLLL +NL N Sbjct: 638 AAKKNQMDIATTLLEYGADANAVTRQG--IASVHLAAQEGHVDMVSLLLGRNANVNLSNK 695 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G T L A Q V + L+ A++ + G T +H +G+ + Sbjct: 696 SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKM-GYTPLHVGCHYGNIK---------- 744 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 I NFL Q + VN K G TPLH AA GH + +LL Sbjct: 745 --IVNFLLQHSAK------------------VNAKTKNGYTPLHQAAQQGHTHIINVLLQ 784 Query: 985 LGASVSEVTIEDGTTIDL 1038 AS +E+T+ T + + Sbjct: 785 NNASPNELTVNGNTALGI 802 Score = 57.4 bits (137), Expect = 2e-07 Identities = 38/114 (33%), Positives = 56/114 (49%), Gaps = 1/114 (0%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 +N GL LH+A+ GHVE V LL A+V T + G+T LH A+ Sbjct: 67 INICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKK----------GNTALHIASL 116 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILSNEPGGQIRT 1236 G A ++L+ GAN+ A++ +G TPL M A H ++ +L N + T Sbjct: 117 AGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLAT 170 Score = 43.1 bits (100), Expect = 0.005 Identities = 26/79 (32%), Positives = 44/79 (55%) Frame = +1 Query: 457 GDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQT 636 G+++ LL+++ ++ + G +PLH AA QGH I+++LL++ N G T Sbjct: 741 GNIKIVNFLLQHSAKVNAKTKNG--YTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNT 798 Query: 637 ALMQACQYGHWEVVQTLML 693 AL A + G+ VV TL + Sbjct: 799 ALGIARRLGYISVVDTLKI 817
>Q2IBB2:CTTB2_RHIFE Cortactin-binding protein 2 - Rhinolophus ferrumequinum (Greater| horseshoe bat) Length = 1663 Score = 87.0 bits (214), Expect = 3e-16 Identities = 68/200 (34%), Positives = 95/200 (47%), Gaps = 1/200 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 768 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 + D NG T + AA GH +C+ L+ A DAD Sbjct: 769 QVDAADK-NGFTPLCAAAAQGHFKCVELLTA---------------------YDAD---- 802 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G+ S T G TPL Sbjct: 803 -----INHTADGGQTPLYLACKNGNKECIKLLLEAGSDRSVKT----------SDGWTPL 847 Query: 1063 HYAACGGNAVCCQLLIARGA 1122 H A GN +LL+ A Sbjct: 848 HAAVDTGNVDSVKLLMYHSA 867 Score = 63.5 bits (153), Expect = 3e-09 Identities = 54/198 (27%), Positives = 90/198 (45%), Gaps = 7/198 (3%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH + V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVDAADKNGF--TPLCAAAAQGHFKCVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHG 765 L +IN GQT L AC+ G+ E ++ L+L + +G T +H A G Sbjct: 796 LTAYDADINHTADGGQTPLYLACKNGNKECIK-LLLEAGSDRSVKTSDGWTPLHAAVDTG 854 Query: 766 HARCLRLVLADYVPSIPNFLNQTKHRSSE-EVSDADFDDDGLVK------MVNWKADGGL 924 + ++L++ P+ +FL++ + S + + +G K ++N G Sbjct: 855 NVDSVKLLMYHSAPARGHFLHEEEPESGVCGLDGGEGSPEGTAKPVVPADLINQADREGW 914 Query: 925 TPLHMAALNGHVECVQLL 978 T H+AA G C+++L Sbjct: 915 TAAHIAASKGFKNCLEIL 932
>Q9Y283:INVS_HUMAN Inversin - Homo sapiens (Human)| Length = 1065 Score = 86.7 bits (213), Expect = 4e-16 Identities = 85/290 (29%), Positives = 134/290 (46%), Gaps = 37/290 (12%) Frame = +1 Query: 475 RALLEYNPR--LARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRG--QTAL 642 R +L+ P L + + GR +PLH+A A G+ +V +L S N+ +Y +T L Sbjct: 202 RCILDAAPTESLLNWQDYEGR-TPLHFAVADGNVTVVDVLT-SYESCNITSYDNLFRTPL 259 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNF 822 A GH ++V L+ N + G T +H+AA A +++ L PS+ + Sbjct: 260 HWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKH--PSVKDD 317 Query: 823 LNQTKHRSSEEVSDADFDDDGLVKMVNWKAD---------GGLTPLHMAALNGHVECVQL 975 + + R+S + DD L M++ K+D GG T LH AAL+GHV V+L Sbjct: 318 -SDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGG-TALHAAALSGHVSTVKL 375 Query: 976 LLDLGASVS----------------------EVTIEDGTTIDLLGS-GSTPLHYAACGGN 1086 LL+ A V + I+ G +DL+ G + LH+AA GGN Sbjct: 376 LLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGN 435 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLM-VAHSWHRNSIEEILSNEPGGQIR 1233 A CQ+LI N ++ +G TPL A+ + N + ++ N I+ Sbjct: 436 ADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQ 485 Score = 77.0 bits (188), Expect = 3e-13 Identities = 59/208 (28%), Positives = 105/208 (50%), Gaps = 7/208 (3%) Frame = +1 Query: 520 FGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 +GG + LH AA GH V LLLE+ +++ + T L +AC+ GH +V+QTL+ Sbjct: 356 YGG--TALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV-PSIPNFLNQTKHRSSEEVSDADFD 876 A + D +G + +H+AAL G+A ++++ + + P++ ++ +T + + + + Sbjct: 414 ARVDLVDQ-DGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA---AYGGYI 469 Query: 877 DDGLVKMVNWKAD------GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 + V M N AD G T LH + NG+++ ++LLLD A +++ + Sbjct: 470 NCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNE------ 522 Query: 1039 LGSGSTPLHYAACGGNAVCCQLLIARGA 1122 TPL YA G Q ++ GA Sbjct: 523 --ERYTPLDYALLGERHEVIQFMLEHGA 548 Score = 66.6 bits (161), Expect = 4e-10 Identities = 77/299 (25%), Positives = 122/299 (40%), Gaps = 45/299 (15%) Frame = +1 Query: 409 FGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLL 588 F S+ ++ +AA +GD + L+ N L GR +PL Y + L Sbjct: 9 FAGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGR-TPLMYCVLADRLDCADAL 67 Query: 589 LESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGH 768 L++G ++N ++ +TAL A Q G++ ++ L+ AN + D L T +H H Sbjct: 68 LKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKD-LEEMTPLHLTTRHRS 126 Query: 769 ARCLRLVLADYVPSIPNFLNQT---------------------KHRSSEEVSD------- 864 +CL L+L P + ++ KH S+ + D Sbjct: 127 PKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186 Query: 865 ---ADFDDDGLV-------------KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGAS 996 A+ D V ++NW+ G TPLH A +G+V V +L S Sbjct: 187 HWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL----TS 242 Query: 997 VSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG-ANLAAKNASGSTPLMVA 1170 I T+ D L TPLH+AA G+A LL+ R + ++ G+TPL A Sbjct: 243 YESCNI---TSYDNL--FRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
>Q6JAN1:INVS_CANFA Inversin - Canis familiaris (Dog)| Length = 1081 Score = 86.7 bits (213), Expect = 4e-16 Identities = 85/290 (29%), Positives = 134/290 (46%), Gaps = 37/290 (12%) Frame = +1 Query: 475 RALLEYNPR--LARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRG--QTAL 642 R +L+ P L + + GR +PLH+A A G+ +V +L S N+ +Y +T L Sbjct: 202 RCILDAAPTESLLNWQDYEGR-TPLHFAVADGNVTVVDVLT-SYESCNITSYDNLFRTPL 259 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNF 822 A GH ++V L+ N + G T +H+AA A +++ L PS+ + Sbjct: 260 HWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKH--PSVKDD 317 Query: 823 LNQTKHRSSEEVSDADFDDDGLVKMVNWKAD---------GGLTPLHMAALNGHVECVQL 975 + + R+S + DD L M++ K+D GG T LH AAL+GHV V+L Sbjct: 318 -SDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGG-TALHAAALSGHVSTVKL 375 Query: 976 LLDLGASVS----------------------EVTIEDGTTIDLLGS-GSTPLHYAACGGN 1086 LL+ A V + I+ G +DL+ G + LH+AA GGN Sbjct: 376 LLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGN 435 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLM-VAHSWHRNSIEEILSNEPGGQIR 1233 A CQ+LI N ++ +G TPL A+ + N + ++ N I+ Sbjct: 436 ADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQ 485 Score = 77.0 bits (188), Expect = 3e-13 Identities = 59/208 (28%), Positives = 105/208 (50%), Gaps = 7/208 (3%) Frame = +1 Query: 520 FGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 +GG + LH AA GH V LLLE+ +++ + T L +AC+ GH +V+QTL+ Sbjct: 356 YGG--TALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV-PSIPNFLNQTKHRSSEEVSDADFD 876 A + D +G + +H+AAL G+A ++++ + + P++ ++ +T + + + + Sbjct: 414 ARVDLVDQ-DGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA---AYGGYI 469 Query: 877 DDGLVKMVNWKAD------GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 + V M N AD G T LH + NG+++ ++LLLD A +++ + Sbjct: 470 NCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNE------ 522 Query: 1039 LGSGSTPLHYAACGGNAVCCQLLIARGA 1122 TPL YA G Q ++ GA Sbjct: 523 --ERYTPLDYALLGERHEVIQFMLEHGA 548 Score = 67.4 bits (163), Expect = 2e-10 Identities = 78/299 (26%), Positives = 122/299 (40%), Gaps = 45/299 (15%) Frame = +1 Query: 409 FGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLL 588 F S+ ++ +AA +GD L+ N L GR +PL Y + L Sbjct: 9 FSGSSLASQVHAAAINGDKGALHRLIIGNSALKDKEDQFGR-TPLMYCVLADRLDCADAL 67 Query: 589 LESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGH 768 L++G ++N ++ +TAL A Q G++ ++ L+ AN + D L T +H A H Sbjct: 68 LKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKD-LEEMTPLHLATRHKS 126 Query: 769 ARCLRLVLADYVPSIPNFLNQT---------------------KHRSSEEVSD------- 864 +CL L+L P + ++ KH S+ + D Sbjct: 127 PKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPL 186 Query: 865 ---ADFDDDGLV-------------KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGAS 996 A+ D V ++NW+ G TPLH A +G+V V +L S Sbjct: 187 HWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVL----TS 242 Query: 997 VSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG-ANLAAKNASGSTPLMVA 1170 I T+ D L TPLH+AA G+A LL+ R + ++ G+TPL A Sbjct: 243 YESCNI---TSYDNL--FRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296
>Q71S22:INVSA_XENLA Inversin-A - Xenopus laevis (African clawed frog)| Length = 1007 Score = 85.9 bits (211), Expect = 6e-16 Identities = 73/257 (28%), Positives = 127/257 (49%), Gaps = 10/257 (3%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLA--RYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLR 618 AA G + R +LE +P L R +GG + LH A+ G V +LLE+ V+++ Sbjct: 325 AAGKGSDEVVRTMLELDPELEVNRTDKYGG--TALHAASLSGQITTVRILLENRVQVDAV 382 Query: 619 NYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLAD 798 + TAL +AC+ GH EV+ TL+ A +H D +G + +H+AAL G+A ++++ + Sbjct: 383 DVMKHTALFRACEMGHREVISTLIKGGAKVHLVD-KDGRSPLHWAALGGNANVCQILIEN 441 Query: 799 YV-PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKAD------GGLTPLHMAALNGH 957 + P ++ +T + + + + V M N KAD G T LH + NG+ Sbjct: 442 NINPDAQDYEGRTPLQCA---AYGGYIGCMEVLMEN-KADPNIQDKNGRTALHWSCNNGY 497 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGA-NLAA 1134 ++ V+LLL A +++ + TPL YA GG+ Q ++ GA ++AA Sbjct: 498 LDAVKLLLGYSAFPNQMENTE--------ERYTPLDYALLGGHQEVIQFMLEHGALSIAA 549 Query: 1135 KNASGSTPLMVAHSWHR 1185 ++ + + H+ Sbjct: 550 IQDIAASKIQAVYKGHK 566 Score = 77.0 bits (188), Expect = 3e-13 Identities = 70/236 (29%), Positives = 106/236 (44%), Gaps = 3/236 (1%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN--ANI 708 +PLHYAA + V +LL + + G+TA M A G EVV+T++ + + Sbjct: 287 TPLHYAAQGNCPDTVRVLLSHISVRDEADLEGRTAFMWAAGKGSDEVVRTMLELDPELEV 346 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 +RTD GGTA+H A+L G +R++L + V + ++ KH Sbjct: 347 NRTDKY-GGTALHAASLSGQITTVRILLENRVQ--VDAVDVMKH---------------- 387 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 T L A GH E + L+ GA V V + G +PLH+ Sbjct: 388 ------------TALFRACEMGHREVISTLIKGGAKVHLVDKD----------GRSPLHW 425 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLM-VAHSWHRNSIEEILSNEPGGQIR 1233 AA GGNA CQ+LI N A++ G TPL A+ + +E ++ N+ I+ Sbjct: 426 AALGGNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNIQ 481 Score = 62.0 bits (149), Expect = 1e-08 Identities = 70/253 (27%), Positives = 108/253 (42%), Gaps = 13/253 (5%) Frame = +1 Query: 442 SAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 +AA GD L+ +P + GR +PL Y+ LL+ G ++N + Sbjct: 16 AAAVTGDKTTLLKLIASSPEVIDQEDQLGR-TPLMYSVLGDRRSCAEALLKHGAQVNHPD 74 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADY 801 G+TAL A Q G+ +++ L+ A+ D L TA+H + H RCL L+L Sbjct: 75 RSGRTALHLAAQTGNHRLLKLLLSRKADCTHRD-LRDITAVHLSTRHQDTRCLALILKYT 133 Query: 802 VPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM-------VNWKADGGLTPLHMAALNGHV 960 P + +Q K + A ++ V++ + G PLH AA GH Sbjct: 134 PPGQVDAQDQRKQTALH--WSAYYNRPRHVRLLVRHGSNIGIPDTEGKIPLHWAA--GHK 189 Query: 961 E-----CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA-RGA 1122 + V+ LL+ + S + +D G TPLH A GN +LL + RG Sbjct: 190 DPEAALTVRCLLEAAPTESLLNWQD-------YEGRTPLHLAVGDGNQEVVRLLTSYRGC 242 Query: 1123 NLAAKNASGSTPL 1161 N+A + TPL Sbjct: 243 NVAPYDNLFRTPL 255 Score = 41.2 bits (95), Expect = 0.018 Identities = 64/279 (22%), Positives = 106/279 (37%), Gaps = 46/279 (16%) Frame = +1 Query: 472 ARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE--------------- 606 A ALL++ ++ G + LH AA G+H ++ LLL + Sbjct: 60 AEALLKHGAQVNHPDRSG--RTALHLAAQTGNHRLLKLLLSRKADCTHRDLRDITAVHLS 117 Query: 607 --------------------INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYL 726 ++ ++ R QTAL + Y V+ L+ +NI D Sbjct: 118 TRHQDTRCLALILKYTPPGQVDAQDQRKQTALHWSAYYNRPRHVRLLVRHGSNIGIPD-T 176 Query: 727 NGGTAIHFAALHGHARCLRLV--LADYVPSIPNFLNQTKH--RSSEEVSDADFDDDGLVK 894 G +H+AA H V L + P+ + LN + R+ ++ D + + + Sbjct: 177 EGKIPLHWAAGHKDPEAALTVRCLLEAAPT-ESLLNWQDYEGRTPLHLAVGDGNQEVVRL 235 Query: 895 MVNWKADGGL-------TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS 1053 + +++ TPLH AAL G+ LLL+ S I G+ Sbjct: 236 LTSYRGCNVAPYDNLFRTPLHWAALLGYTPIAHLLLETNNS---------PNIPSDSQGA 286 Query: 1054 TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 TPLHYAA G ++L++ + + G T M A Sbjct: 287 TPLHYAAQGNCPDTVRVLLSHISVRDEADLEGRTAFMWA 325
>Q2IBE6:CTTB2_PONPY Cortactin-binding protein 2 - Pongo pygmaeus (Orangutan)| Length = 1663 Score = 85.9 bits (211), Expect = 6e-16 Identities = 70/215 (32%), Positives = 103/215 (47%), Gaps = 6/215 (2%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 768 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH C+ L++A DA+ Sbjct: 769 QVNAADK-NGFTPLCAAAAQGHFECVELLIA---------------------YDAN---- 802 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ ECV+LLL+ G + S T + G TP+ Sbjct: 803 -----INHAADGGQTPLYLACKNGNKECVKLLLEAGTNRSVKTTD----------GWTPV 847 Query: 1063 HYAACGGNAVCCQLLI-----ARGANLAAKNASGS 1152 H A GN +LL+ ARG + + + S Sbjct: 848 HAAVDTGNVDSLKLLMYHRIPARGNSFNEEESESS 882 Score = 74.3 bits (181), Expect = 2e-12 Identities = 64/202 (31%), Positives = 95/202 (47%), Gaps = 11/202 (5%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGF--TPLCAAAAQGHFECVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML--FNANIHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ G+ E V+ L+ N ++ TD G T +H A Sbjct: 796 LIAYDANINHAADGGQTPLYLACKNGNKECVKLLLEAGTNRSVKTTD---GWTPVHAAVD 852 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD---GLVK------MVNWKA 912 G+ L+L++ +P+ N N+ + SS V D D +D G+ K ++N Sbjct: 853 TGNVDSLKLLMYHRIPARGNSFNEEESESS--VFDLDGGEDSPEGISKPVIPADLINHAN 910 Query: 913 DGGLTPLHMAALNGHVECVQLL 978 G T H+AA G C+++L Sbjct: 911 REGWTAAHIAASKGFKNCLEIL 932
>Q07DX4:CTTB2_HYLLE Cortactin-binding protein 2 - Hylobates leucogenys (White-cheeked| gibbon) Length = 1663 Score = 85.9 bits (211), Expect = 6e-16 Identities = 69/215 (32%), Positives = 103/215 (47%), Gaps = 6/215 (2%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 768 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH C+ L++A DA+ Sbjct: 769 QVNAADK-NGFTPLCAAAAQGHFECVELLIA---------------------YDAN---- 802 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G + S T + G TP+ Sbjct: 803 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTD----------GWTPV 847 Query: 1063 HYAACGGNAVCCQLL-----IARGANLAAKNASGS 1152 H A GN +LL +ARG + + + S Sbjct: 848 HAAVDTGNVDSLKLLMYHRILARGNSFNEEGSESS 882 Score = 68.2 bits (165), Expect = 1e-10 Identities = 58/200 (29%), Positives = 92/200 (46%), Gaps = 9/200 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGF--TPLCAAAAQGHFECVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML--FNANIHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ G+ E ++ L+ N ++ TD G T +H A Sbjct: 796 LIAYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTD---GWTPVHAAVD 852 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSE-EVSDADFDDDGLVK------MVNWKADG 918 G+ L+L++ + + N N+ SS ++ + +G+ K ++N Sbjct: 853 TGNVDSLKLLMYHRILARGNSFNEEGSESSVFDLDGGEESPEGISKPVVPADLINHANRE 912 Query: 919 GLTPLHMAALNGHVECVQLL 978 G T H+AA G C+++L Sbjct: 913 GWTAAHIAASKGFKNCLEIL 932 Score = 63.2 bits (152), Expect = 4e-09 Identities = 62/214 (28%), Positives = 93/214 (43%), Gaps = 6/214 (2%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLSAEAQVNA 772 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH+E V+ L+ ++ANI H D G T ++ A +G+ C++L+L Sbjct: 773 ADKNGFTPLCAAAAQGHFECVELLIAYDANINHAAD--GGQTPLYLACKNGNKECIKLLL 830 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G TP+H A G+V+ ++ Sbjct: 831 ----------------------------EAGTNRSV--KTTDGWTPVHAAVDTGNVDSLK 860 Query: 973 LL-----LDLGASVSEVTIEDGTTIDLLGSGSTP 1059 LL L G S +E E + DL G +P Sbjct: 861 LLMYHRILARGNSFNEEGSE-SSVFDLDGGEESP 893
>Q2IBF8:CTTB2_EULMM Cortactin-binding protein 2 - Eulemur macaco macaco (Black lemur)| Length = 1653 Score = 85.9 bits (211), Expect = 6e-16 Identities = 67/200 (33%), Positives = 96/200 (48%), Gaps = 1/200 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 700 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 759 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH C+ L++A DA Sbjct: 760 QVNAAD-KNGFTPLCAAAAQGHFECVELLIA---------------------YDAH---- 793 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G S T + G TP+ Sbjct: 794 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRD----------GWTPV 838 Query: 1063 HYAACGGNAVCCQLLIARGA 1122 H A GN +LL+ GA Sbjct: 839 HAAVDTGNVDSLKLLMYHGA 858 Score = 62.0 bits (149), Expect = 1e-08 Identities = 54/187 (28%), Positives = 84/187 (44%), Gaps = 1/187 (0%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 705 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLNAEAQVNA 763 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH+E V+ L+ ++A+I H D G T ++ A +G+ C++L+L Sbjct: 764 ADKNGFTPLCAAAAQGHFECVELLIAYDAHINHAAD--GGQTPLYLACKNGNKECIKLLL 821 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G TP+H A G+V+ ++ Sbjct: 822 ----------------------------EAGTDRSV--KTRDGWTPVHAAVDTGNVDSLK 851 Query: 973 LLLDLGA 993 LL+ GA Sbjct: 852 LLMYHGA 858
>Q9ULJ7:ANR50_HUMAN Ankyrin repeat domain-containing protein 50 - Homo sapiens (Human)| Length = 1375 Score = 85.5 bits (210), Expect = 8e-16 Identities = 64/227 (28%), Positives = 100/227 (44%), Gaps = 1/227 (0%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PL AA +GH ++V LLLE G +++ + G+T L+ A GH VV TL+ + A + Sbjct: 696 TPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDS 755 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 D G T + A+ G+ +R +L D D+ Sbjct: 756 ID-SEGRTVLSIASAQGNVEVVRTLL-----------------------DRGLDE----- 786 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 N + D G TPLHMAA GH + L++ GA +E+ G P A+ Sbjct: 787 --NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEID----------NDGRIPFILAS 834 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVAH-SWHRNSIEEILSN 1212 G+ C Q+L+ +N+ + G L VA HR+ +E + S+ Sbjct: 835 QEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSH 881 Score = 84.3 bits (207), Expect = 2e-15 Identities = 92/339 (27%), Positives = 136/339 (40%), Gaps = 56/339 (16%) Frame = +1 Query: 367 LWASMGFLSLVGNSFGCSASGER--------LVSAARDGDLQEARALLEYNPRLARYSTF 522 L A G +V GC A+ L SAA G + ALL ++ Sbjct: 530 LAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVD--CAD 587 Query: 523 GGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 + L AA GH +IV LL+ G E+N + G+TAL+ A GH E+V+ L+ A Sbjct: 588 ADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGA 647 Query: 703 NIHRTDYLNGGTAIHFAAL-----HGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDA 867 ++ D ++G TA+ AAL GHA + L++ EV Sbjct: 648 EVNHED-VDGRTALSVAALCVPASKGHASVVSLLI----------------DRGAEVDHC 690 Query: 868 DFDD---------DGLVKMVNWKADGGL----------TPLHMAALNGHVECVQLLLDLG 990 D D +G V +V+ +GG TPL AA GH V LL G Sbjct: 691 DKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWG 750 Query: 991 ASVSEVTIEDGTTIDLLG-----------------------SGSTPLHYAACGGNAVCCQ 1101 A+V + E T + + +G TPLH AA G+ + C+ Sbjct: 751 AAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICE 810 Query: 1102 LLIARGANLAAKNASGSTPLMVA-HSWHRNSIEEILSNE 1215 LI +GA + G P ++A H + ++ +L N+ Sbjct: 811 ALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENK 849 Score = 81.6 bits (200), Expect = 1e-14 Identities = 79/253 (31%), Positives = 109/253 (43%), Gaps = 1/253 (0%) Frame = +1 Query: 415 CSASGERLVS-AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 C ++G L++ AA G L L+ L G ++PL AA QGH ++V+ L+ Sbjct: 487 CDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHG--HTPLTLAARQGHTKVVNCLI 544 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 G IN + G TAL A GH EVV L+ + D + TA+ AA GH Sbjct: 545 GCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCAD-ADSRTALRAAAWGGHE 603 Query: 772 RCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALN 951 + LN +H EV+ AD + G T L AA Sbjct: 604 DIV--------------LNLLQH--GAEVNKAD--------------NEGRTALIAAAYM 633 Query: 952 GHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLA 1131 GH E V+ LLD GA V+ ++ T + + L A G+A LLI RGA + Sbjct: 634 GHREIVEHLLDHGAEVNHEDVDGRTALSV-----AALCVPASKGHASVVSLLIDRGAEVD 688 Query: 1132 AKNASGSTPLMVA 1170 + G TPL+VA Sbjct: 689 HCDKDGMTPLLVA 701 Score = 76.6 bits (187), Expect = 4e-13 Identities = 79/293 (26%), Positives = 122/293 (41%), Gaps = 27/293 (9%) Frame = +1 Query: 373 ASMGFLSLVGNSFGCSASGERLVSAAR--------DGDLQEARALLEYNPRLARYSTFGG 528 ASMG S+V A+ + + S R G+++ R LL+ G Sbjct: 735 ASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGW 794 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 +PLH AA +GH I L+E G N + G+ + A Q GH++ VQ L+ +NI Sbjct: 795 --TPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI 852 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLAD---------------YVPSIPNFLNQTKH- 840 + Y +G A+ AAL GH + L+ + Y+ ++ N L ++ Sbjct: 853 DQRGY-DGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYF 911 Query: 841 ---RSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVT 1011 ++ E SDA+ G T LH++ GH+E VQ+L+ A V+ Sbjct: 912 LENGANVEASDAE----------------GRTALHVSCWQGHMEMVQVLIAYHADVNAAD 955 Query: 1012 IEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 E + L AA G+ QLLI GA + G+T L +A Sbjct: 956 NEKRSA----------LQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIA 998 Score = 62.4 bits (150), Expect = 7e-09 Identities = 68/290 (23%), Positives = 121/290 (41%), Gaps = 33/290 (11%) Frame = +1 Query: 439 VSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLR 618 + A+++G + LLE + + + GRN+ L AA +GH +IV LL G ++N + Sbjct: 831 ILASQEGHYDCVQILLENKSNIDQRG-YDGRNA-LRVAALEGHRDIVELLFSHGADVNCK 888 Query: 619 NY---------------------------------RGQTALMQACQYGHWEVVQTLMLFN 699 + G+TAL +C GH E+VQ L+ ++ Sbjct: 889 DADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYH 948 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 A+++ D +A+ AA GH + ++L++ + Sbjct: 949 ADVNAADN-EKRSALQSAAWQGHVKVVQLLI----------------------------E 979 Query: 880 DGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTP 1059 G V V+ + G T L +AA GH++ VQ+LL+ GA + G T Sbjct: 980 HGAV--VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHAD----------QFGRTA 1027 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILS 1209 + AA G++ +LL GA+ + +G +P V H+ + ++ + S Sbjct: 1028 MRVAAKNGHSQIIKLLEKYGAS----SLNGCSPSPV-HTMEQKPLQSLSS 1072
>Q9VUX2:MIB_DROME E3 ubiquitin-protein ligase mind-bomb - Drosophila melanogaster| (Fruit fly) Length = 1226 Score = 85.1 bits (209), Expect = 1e-15 Identities = 77/266 (28%), Positives = 117/266 (43%), Gaps = 6/266 (2%) Frame = +1 Query: 403 NSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVS 582 N G A L +A+++G ++ + LL + + G R +H+AA ++ Sbjct: 561 NVNGVFAGHTALQAASQNGHIEVIQVLLRHAVDVEIEDKDGDR--AVHHAAFGDEAAVIE 618 Query: 583 LLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALH 762 +L ++G ++N RN R QT+L A GH VV+TL+ + D G T +H A Sbjct: 619 ILAKAGADLNARNKRRQTSLHIAVNKGHLNVVKTLLTLGCHPSLQD-SEGDTPLHDAISK 677 Query: 763 GHARCLRLVL---ADYVPSIPNFLNQTKH---RSSEEVSDADFDDDGLVKMVNWKADGGL 924 H L L+L AD + N N H + + +V K D G Sbjct: 678 EHDEMLSLLLDFGADITLNNNNGFNALHHAALKGNPSAMKILLTKTNRPWIVEEKKDDGY 737 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 T LH+AALN HVE +LL+ +G + D ++L T LH A + +L Sbjct: 738 TALHLAALNNHVEIAELLVHMGKANM-----DRQNVNL----QTALHLAVERQHVQIVKL 788 Query: 1105 LIARGANLAAKNASGSTPLMVAHSWH 1182 L+ GA+L + G TPL A H Sbjct: 789 LVQDGADLNIPDKDGDTPLHEALRHH 814
>Q8UVC3:INVS_CHICK Inversin - Gallus gallus (Chicken)| Length = 1106 Score = 85.1 bits (209), Expect = 1e-15 Identities = 81/292 (27%), Positives = 130/292 (44%), Gaps = 35/292 (11%) Frame = +1 Query: 463 LQEARALLEYNPR--LARYSTFGGRNSPLHYAAAQGHHEIVSLLLE-SGVEINLRNYRGQ 633 + + +LE P L + + GR +PLH+A A G+ +V +L G + + + Sbjct: 198 IHTVKCILEAAPTESLLNWQDYEGR-TPLHFAVADGNVAVVDVLTSYEGCNVTSYDNLFR 256 Query: 634 TALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSI 813 T L A GH ++V L+ N G T +H+AA A + + L PS+ Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKFGTIPSDSQGATPLHYAAQSNFAETVEVFLKH--PSV 314 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGL--------TPLHMAALNGHVECV 969 + + + R+S + D+ + M++ K D + T LH AAL+GHV V Sbjct: 315 KDD-SDLEGRTSFMWAAGKGSDNVIRTMLDLKLDIDINMTDKYAGTALHAAALSGHVSTV 373 Query: 970 QLLLDLGASVS----------------------EVTIEDGTTIDLLGS-GSTPLHYAACG 1080 +LLL+ A V + I+ G +DL+ G +PLH+AA G Sbjct: 374 KLLLERNAQVDALDVMKHTPLFRACEMGHKEVIQTLIKGGARVDLVDQDGHSPLHWAALG 433 Query: 1081 GNAVCCQLLIARGANLAAKNASGSTPLM-VAHSWHRNSIEEILSNEPGGQIR 1233 GNA CQ+LI N ++ +G TPL A+ + N + +L N I+ Sbjct: 434 GNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMVVLLENNADPNIQ 485 Score = 72.8 bits (177), Expect = 5e-12 Identities = 61/233 (26%), Positives = 107/233 (45%), Gaps = 7/233 (3%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G R +L+ + T + LH AA GH V LLLE +++ + Sbjct: 329 AAGKGSDNVIRTMLDLKLDIDINMTDKYAGTALHAAALSGHVSTVKLLLERNAQVDALDV 388 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 T L +AC+ GH EV+QTL+ A + D +G + +H+AAL G+A ++++ + + Sbjct: 389 MKHTPLFRACEMGHKEVIQTLIKGGARVDLVDQ-DGHSPLHWAALGGNADVCQILIENKI 447 Query: 805 -PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKAD------GGLTPLHMAALNGHVE 963 P++ ++ +T + + + +V ++ AD G T LH NG+++ Sbjct: 448 NPNVQDYAGRTPLQCAAYGGYINC----MVVLLENNADPNIQDKEGRTALHWLCNNGYLD 503 Query: 964 CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGA 1122 ++LLL A + + + TPL YA G + Q ++ GA Sbjct: 504 AIKLLLGFDAFPNHMENSE--------ERYTPLDYALLGEHHEVIQFMLEHGA 548 Score = 68.2 bits (165), Expect = 1e-10 Identities = 79/297 (26%), Positives = 124/297 (41%), Gaps = 17/297 (5%) Frame = +1 Query: 406 SFGCSASGERLVS----AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHE 573 S C SG L S AA +GD L+ N L GR +PL Y + Sbjct: 4 SANCLFSGSSLASEVHAAAVNGDKSTLLKLIAGNSELKDKEDQFGR-TPLMYCVLADRVD 62 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 LL++G ++N + +TAL A Q G++ ++ L+ N + D L G T +H Sbjct: 63 CAEALLKAGADVNRADRSRRTALHLAAQKGNYRFMKLLLARRGNWMQKD-LEGMTPLHLT 121 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADG----- 918 H +CL L+L P + Q +++ + A +++ VK++ K D Sbjct: 122 TRHKSPKCLALLLKHMAPGEVD--TQDRNKQTALHWSAYYNNPEHVKLL-IKHDSNIGIP 178 Query: 919 ---GLTPLHMAALN---GHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACG 1080 G PLH AA N + V+ +L+ + S + +D G TPLH+A Sbjct: 179 DIEGKIPLHWAANNKDPSAIHTVKCILEAAPTESLLNWQD-------YEGRTPLHFAVAD 231 Query: 1081 GNAVCCQLLIA-RGANLAAKNASGSTPL-MVAHSWHRNSIEEILSNEPGGQIRTLPS 1245 GN +L + G N+ + + TPL A H + +L G T+PS Sbjct: 232 GNVAVVDVLTSYEGCNVTSYDNLFRTPLHWAALLGHAQIVHLLLERNKFG---TIPS 285
>Q09YM8:CTTB2_RABIT Cortactin-binding protein 2 - Oryctolagus cuniculus (Rabbit)| Length = 1664 Score = 85.1 bits (209), Expect = 1e-15 Identities = 69/212 (32%), Positives = 99/212 (46%), Gaps = 1/212 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++ N G +AL A GH + V+ L+ A Sbjct: 710 GRPTLLQQAAAQGNVTLLSMLLNEEGLDTNYSCEDGHSALYSAATNGHADCVRLLLNAEA 769 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ + NG T + AA GH CL L+LA SDAD Sbjct: 770 QVNAAEK-NGFTPLCAAAAQGHFECLELLLA---------------------SDAD---- 803 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 VN ADGG TPL++A NG+ +C++LLL+ G S T + G TP+ Sbjct: 804 -----VNHAADGGQTPLYLACKNGNTDCIKLLLEAGTDRSIKTRD----------GWTPV 848 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTP 1158 H A GN +LL+ A +++ P Sbjct: 849 HAAVDTGNVDSLKLLMYYQAPARGNSSNEEEP 880 Score = 68.2 bits (165), Expect = 1e-10 Identities = 57/199 (28%), Positives = 90/199 (45%), Gaps = 8/199 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA +G R LL ++ G +PL AAAQGH E + L Sbjct: 739 NYSCEDGHSALYSAATNGHADCVRLLLNAEAQVNAAEKNGF--TPLCAAAAQGHFECLEL 796 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT-DYLNGGTAIHFAALH 762 LL S ++N GQT L AC+ G+ + ++ +L A R+ +G T +H A Sbjct: 797 LLASDADVNHAADGGQTPLYLACKNGNTDCIK--LLLEAGTDRSIKTRDGWTPVHAAVDT 854 Query: 763 GHARCLRLVLADYVPSIPNFLNQTKHRSS-------EEVSDADFDDDGLVKMVNWKADGG 921 G+ L+L++ P+ N N+ + S EE S+ + ++N G Sbjct: 855 GNVDSLKLLMYYQAPARGNSSNEEEPESGAFARDGGEESSEGTSEPVVSADLINHADREG 914 Query: 922 LTPLHMAALNGHVECVQLL 978 T H+AA G C+++L Sbjct: 915 WTAAHIAASKGFKNCLEIL 933 Score = 67.4 bits (163), Expect = 2e-10 Identities = 71/228 (31%), Positives = 92/228 (40%), Gaps = 2/228 (0%) Frame = +1 Query: 493 NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWE 672 NP A S G +S L A G ++ LL SG L T L QA G+ Sbjct: 670 NPVSASTSRPGASDSLL--VTASGWSPSLTPLLMSGGPAPLAGR--PTLLQQAAAQGN-- 723 Query: 673 VVQTLMLFNANIHRTDYL--NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRS 846 V ML N T+Y +G +A++ AA +GHA C+RL+L Sbjct: 724 VTLLSMLLNEEGLDTNYSCEDGHSALYSAATNGHADCVRLLL------------------ 765 Query: 847 SEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGT 1026 VN G TPL AA GH EC++LLL A V+ DG Sbjct: 766 ------------NAEAQVNAAEKNGFTPLCAAAAQGHFECLELLLASDADVNHAA--DG- 810 Query: 1027 TIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G TPL+ A GN C +LL+ G + + K G TP+ A Sbjct: 811 -------GQTPLYLACKNGNTDCIKLLLEAGTDRSIKTRDGWTPVHAA 851
>Q9ERK0:RIPK4_MOUSE Receptor-interacting serine/threonine-protein kinase 4 - Mus musculus| (Mouse) Length = 786 Score = 84.7 bits (208), Expect = 1e-15 Identities = 76/256 (29%), Positives = 104/256 (40%), Gaps = 1/256 (0%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA++GD R LLE N + F GR +P+H A G IV LL GV++ L+ Sbjct: 513 AAQNGDEASTRLLLEKNASVNEVD-FEGR-TPMHVACQHGQENIVRTLLRRGVDVGLQGK 570 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 L A GH +V+ L L+G T +H AA GH R R+++ Sbjct: 571 DAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILI---- 626 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 L VN + TPLH+AA GH +LLL Sbjct: 627 --------------------------DLCSDVNICSLQAQTPLHVAAETGHTSTARLLLH 660 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL- 1161 GA +T E G T LH AA G+ +LLI A++ A+ T L Sbjct: 661 RGAGKEALTSE----------GYTALHLAAQNGHLATVKLLIEEKADVMARGPLNQTALH 710 Query: 1162 MVAHSWHRNSIEEILS 1209 + A H +EE++S Sbjct: 711 LAAARGHSEVVEELVS 726 Score = 73.2 bits (178), Expect = 4e-12 Identities = 65/237 (27%), Positives = 107/237 (45%), Gaps = 9/237 (3%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 ++PLH A + IV LLL +N ++ TAL A Q G + L+ NA+++ Sbjct: 474 STPLHMAVERKGRGIVELLLARKTSVNAKDEDQWTALHFAAQNGDEASTRLLLEKNASVN 533 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPS--------IPNFLNQTKHRSSEEVSDA 867 D+ G T +H A HG +R +L V +P L+ + + Sbjct: 534 EVDF-EGRTPMHVACQHGQENIVRTLLRRGVDVGLQGKDAWLP--LHYAAWQGHLPIVKL 590 Query: 868 DFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS 1047 G+ VN + G TPLH+AA GH ++L+DL + V+ +++ Sbjct: 591 LAKQPGV--SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNICSLQ---------- 638 Query: 1048 GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILSNE 1215 TPLH AA G+ +LL+ RGA A + G T L + A + H +++ ++ + Sbjct: 639 AQTPLHVAAETGHTSTARLLLHRGAGKEALTSEGYTALHLAAQNGHLATVKLLIEEK 695 Score = 68.6 bits (166), Expect = 1e-10 Identities = 54/190 (28%), Positives = 92/190 (48%), Gaps = 4/190 (2%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G L + L + T GR +PLH AA +GH+ + +L++ ++N+ + Sbjct: 579 AAWQGHLPIVKLLAKQPGVSVNAQTLDGR-TPLHLAAQRGHYRVARILIDLCSDVNICSL 637 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL---A 795 + QT L A + GH + L+ A G TA+H AA +GH ++L++ A Sbjct: 638 QAQTPLHVAAETGHTSTARLLLHRGAGKEALT-SEGYTALHLAAQNGHLATVKLLIEEKA 696 Query: 796 DYVPSIPNFLNQTK-HRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 D + P LNQT H ++ ++ +++ + GL+ LH+AA H + V+ Sbjct: 697 DVMARGP--LNQTALHLAAARGHSEVVEELVSADLIDLSDEQGLSALHLAAQGRHSQTVE 754 Query: 973 LLLDLGASVS 1002 LL GA ++ Sbjct: 755 TLLKHGAHIN 764 Score = 66.2 bits (160), Expect = 5e-10 Identities = 70/253 (27%), Positives = 108/253 (42%), Gaps = 9/253 (3%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 S LH A G E V LL + NL N +G T L A + +V+ L+ +++ Sbjct: 442 SLLHLAVEAGQEECVKWLLLNNANPNLTNRKGSTPLHMAVERKGRGIVELLLARKTSVNA 501 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQT--KHRSSEEVSDADFDDDGL 888 D + TA+HFAA +G RL+L +N+ + R+ V+ ++ + Sbjct: 502 KDE-DQWTALHFAAQNGDEASTRLLLEKNAS-----VNEVDFEGRTPMHVACQHGQENIV 555 Query: 889 VKMVNWKADGGLT------PLHMAALNGHVECVQLLLDL-GASVSEVTIEDGTTIDLLGS 1047 ++ D GL PLH AA GH+ V+LL G SV+ T++ Sbjct: 556 RTLLRRGVDVGLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLD---------- 605 Query: 1048 GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQ 1227 G TPLH AA G+ ++LI +++ + TPL VA S +L + G+ Sbjct: 606 GRTPLHLAAQRGHYRVARILIDLCSDVNICSLQAQTPLHVAAETGHTSTARLLLHRGAGK 665 Query: 1228 IRTLPSPYLCLPL 1266 Y L L Sbjct: 666 EALTSEGYTALHL 678 Score = 52.8 bits (125), Expect = 6e-06 Identities = 46/168 (27%), Positives = 72/168 (42%), Gaps = 3/168 (1%) Frame = +1 Query: 727 NGGTAIHFAALHGHARCLR-LVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM-- 897 + + +H A G C++ L+L + P++ N T + E + L + Sbjct: 439 SSASLLHLAVEAGQEECVKWLLLNNANPNLTNRKGSTPLHMAVERKGRGIVELLLARKTS 498 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 VN K + T LH AA NG +LLL+ ASV+EV E G TP+H A Sbjct: 499 VNAKDEDQWTALHFAAQNGDEASTRLLLEKNASVNEVDFE----------GRTPMHVACQ 548 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPG 1221 G + L+ RG ++ + PL A I ++L+ +PG Sbjct: 549 HGQENIVRTLLRRGVDVGLQGKDAWLPLHYAAWQGHLPIVKLLAKQPG 596 Score = 33.5 bits (75), Expect = 3.7 Identities = 30/110 (27%), Positives = 47/110 (42%), Gaps = 24/110 (21%) Frame = +1 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTT-----IDLLGSGS-------- 1053 D + LH+A G ECV+ LL L + +T G+T ++ G G Sbjct: 438 DSSASLLHLAVEAGQEECVKWLL-LNNANPNLTNRKGSTPLHMAVERKGRGIVELLLARK 496 Query: 1054 -----------TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 T LH+AA G+ +LL+ + A++ + G TP+ VA Sbjct: 497 TSVNAKDEDQWTALHFAAQNGDEASTRLLLEKNASVNEVDFEGRTPMHVA 546
>Q09YJ3:CTTB2_MUNMU Cortactin-binding protein 2 - Muntiacus muntjak (Barking deer)| (Indian muntjac) Length = 1642 Score = 84.7 bits (208), Expect = 1e-15 Identities = 65/196 (33%), Positives = 96/196 (48%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 702 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 761 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH +C+ L++A DA+ Sbjct: 762 QVNAADK-NGFTPLCAAAAQGHFKCVELLIA---------------------YDAN---- 795 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G S T + G TP+ Sbjct: 796 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRD----------GWTPI 840 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 841 HAAVDTGNVDSLKLLM 856 Score = 64.7 bits (156), Expect = 1e-09 Identities = 56/198 (28%), Positives = 89/198 (44%), Gaps = 7/198 (3%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH + V L Sbjct: 731 NYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGF--TPLCAAAAQGHFKCVEL 788 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT-DYLNGGTAIHFAALH 762 L+ IN GQT L AC+ G+ E ++ +L A R+ +G T IH A Sbjct: 789 LIAYDANINHAADGGQTPLYLACKNGNKECIK--LLLEAGTDRSVKTRDGWTPIHAAVDT 846 Query: 763 GHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK------MVNWKADGGL 924 G+ L+L++ P+ N L + + ++ + +G K ++N G Sbjct: 847 GNVDSLKLLMYHRAPAHGNKLREEPGLAIFDLDQEEERHEGTSKPVVPADLINHADSEGW 906 Query: 925 TPLHMAALNGHVECVQLL 978 T H+AA G C+++L Sbjct: 907 TAAHIAASKGFKNCLEVL 924 Score = 61.6 bits (148), Expect = 1e-08 Identities = 67/255 (26%), Positives = 107/255 (41%), Gaps = 27/255 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 707 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLNAEAQVNA 765 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH++ V+ L+ ++ANI H D G T ++ A +G+ C++L+L Sbjct: 766 ADKNGFTPLCAAAAQGHFKCVELLIAYDANINHAAD--GGQTPLYLACKNGNKECIKLLL 823 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G TP+H A G+V+ ++ Sbjct: 824 ----------------------------EAGTDRSV--KTRDGWTPIHAAVDTGNVDSLK 853 Query: 973 LLL-------------DLGASVSEVTIE----DGTT-----IDLL----GSGSTPLHYAA 1074 LL+ + G ++ ++ E +GT+ DL+ G T H AA Sbjct: 854 LLMYHRAPAHGNKLREEPGLAIFDLDQEEERHEGTSKPVVPADLINHADSEGWTAAHIAA 913 Query: 1075 CGGNAVCCQLLIARG 1119 G C ++L G Sbjct: 914 SKGFKNCLEVLCRHG 928 Score = 57.8 bits (138), Expect = 2e-07 Identities = 39/119 (32%), Positives = 59/119 (49%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL+ A Sbjct: 704 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 761 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 V+ +G TPL AA G+ C +LLIA AN+ G TPL +A Sbjct: 762 QVNAAD----------KNGFTPLCAAAAQGHFKCVELLIAYDANINHAADGGQTPLYLA 810
>Q4UMH6:Y381_RICFE Putative ankyrin repeat protein RF_0381 - Rickettsia felis| (Rickettsia azadi) Length = 1179 Score = 84.3 bits (207), Expect = 2e-15 Identities = 70/237 (29%), Positives = 110/237 (46%), Gaps = 12/237 (5%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH-RT 717 LHYA G+ ++VSLL+ G ++N + G+T L A YG ++V L+ + A+++ +T Sbjct: 741 LHYAVYDGNLDLVSLLISHGADVNAKTNSGETILYSAVDYGSPDLVYLLIAYGADVNAKT 800 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM 897 D NG T +H+A G+ + L+ I N N ++ + G + + Sbjct: 801 D--NGETVLHYAVESGNLDLVSLL-------IHNGANVNNAKTILHFA----AKSGNLNL 847 Query: 898 VNW----------KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS 1047 VNW K + G T LH AA +G++ V L+ A + T S Sbjct: 848 VNWLIKNKADIHAKTNSGETILHFAAESGNLNLVNWLIKNKADIHAKT----------NS 897 Query: 1048 GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILSNE 1215 G T LH+AA GN LI A++ AK SG T L A S + N + ++ N+ Sbjct: 898 GETILHFAAKSGNLNLVNWLIKNKADIHAKTNSGETILHFAAKSGNLNLVNWLIKNK 954 Score = 82.8 bits (203), Expect = 5e-15 Identities = 84/313 (26%), Positives = 136/313 (43%), Gaps = 32/313 (10%) Frame = +1 Query: 394 LVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHE 573 L+ N + + L AA+ G+L L++ + + G + LH+AA G+ Sbjct: 822 LIHNGANVNNAKTILHFAAKSGNLNLVNWLIKNKADIHAKTNSG--ETILHFAAESGNLN 879 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 +V+ L+++ +I+ + G+T L A + G+ +V L+ A+IH +G T +HFA Sbjct: 880 LVNWLIKNKADIHAKTNSGETILHFAAKSGNLNLVNWLIKNKADIHAKTN-SGETILHFA 938 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSD--ADFDDDGLVKM-------VNW 906 A G+ + ++ + K S E + A+ + LV + +N Sbjct: 939 AKSGNLNLVNWLIKNKADI------HAKTNSGETILHFAAESGNLNLVSLLIHNGTDINT 992 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL---LGS---------- 1047 K D GLT LH A +G++ V LL+ G V+ T T + LGS Sbjct: 993 KTDDGLTALHYAVESGNLNLVSLLIHKGIDVNAKTNSGETILHFAVDLGSLDLVSLLMVR 1052 Query: 1048 ----------GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIE 1197 G T LHYA N LL+ GA++ AKN SG TPL A ++ + Sbjct: 1053 GADVNAKTDDGLTALHYAVESDNLALVSLLMVYGADVNAKNNSGETPLHYAVIFNSLDLV 1112 Query: 1198 EILSNEPGGQIRT 1236 +L + G I T Sbjct: 1113 SLLIHN-GADINT 1124 Score = 81.6 bits (200), Expect = 1e-14 Identities = 74/256 (28%), Positives = 118/256 (46%), Gaps = 10/256 (3%) Frame = +1 Query: 424 SGERLVS-AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESG 600 SGE ++ AA+ G+L L++ + + G + LH+AA G+ +V+ L+++ Sbjct: 897 SGETILHFAAKSGNLNLVNWLIKNKADIHAKTNSG--ETILHFAAKSGNLNLVNWLIKNK 954 Query: 601 VEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCL 780 +I+ + G+T L A + G+ +V +L++ N T +G TA+H+A G+ + Sbjct: 955 ADIHAKTNSGETILHFAAESGNLNLV-SLLIHNGTDINTKTDDGLTALHYAVESGNLNLV 1013 Query: 781 RLVLADYVPSIPNFLNQTKHRSSEEVSD--ADFDDDGLVKM-------VNWKADGGLTPL 933 L++ + K S E + D LV + VN K D GLT L Sbjct: 1014 SLLIHKGIDV------NAKTNSGETILHFAVDLGSLDLVSLLMVRGADVNAKTDDGLTAL 1067 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA 1113 H A + ++ V LL+ GA V+ SG TPLHYA + LLI Sbjct: 1068 HYAVESDNLALVSLLMVYGADVNAKN----------NSGETPLHYAVIFNSLDLVSLLIH 1117 Query: 1114 RGANLAAKNASGSTPL 1161 GA++ KN SG T L Sbjct: 1118 NGADINTKNNSGETVL 1133 Score = 81.3 bits (199), Expect = 2e-14 Identities = 67/211 (31%), Positives = 100/211 (47%), Gaps = 1/211 (0%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH-RT 717 LH AA G+ ++ LL ++G ++N + G+T L A + G+ +V+ L+ ANIH +T Sbjct: 642 LHCAAKNGNLDLAKLLAKNGADVNAKTDNGETVLHYAVKSGNLHLVKWLIENQANIHAKT 701 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM 897 D NG T +H+A ++ + L++A AD Sbjct: 702 D--NGETVLHYAVSFNNSDLVYLLIA---------------------YGAD--------- 729 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 VN K D GLT LH A +G+++ V LL+ GA V+ T SG T L+ A Sbjct: 730 VNAKTDNGLTALHYAVYDGNLDLVSLLISHGADVNAKT----------NSGETILYSAVD 779 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G+ LLIA GA++ AK +G T L A Sbjct: 780 YGSPDLVYLLIAYGADVNAKTDNGETVLHYA 810 Score = 44.7 bits (104), Expect = 0.002 Identities = 32/120 (26%), Positives = 62/120 (51%), Gaps = 2/120 (1%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH+A G ++VSLL+ G ++N + G TAL A + + +V LM++ A+++ + Sbjct: 1034 LHFAVDLGSLDLVSLLMVRGADVNAKTDDGLTALHYAVESDNLALVSLLMVYGADVNAKN 1093 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEV--SDADFDDDGLVK 894 +G T +H+A + + L++ + TK+ S E V S +F++ ++K Sbjct: 1094 N-SGETPLHYAVIFNSLDLVSLLIHNGADI------NTKNNSGETVLNSIMEFNNCNILK 1146 Score = 44.3 bits (103), Expect = 0.002 Identities = 19/59 (32%), Positives = 37/59 (62%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 +PLHYA ++VSLL+ +G +IN +N G+T L ++ + ++++ +L A+I+ Sbjct: 1098 TPLHYAVIFNSLDLVSLLIHNGADINTKNNSGETVLNSIMEFNNCNILKSFILGGADIN 1156
>P57078:RIPK4_HUMAN Receptor-interacting serine/threonine-protein kinase 4 - Homo sapiens| (Human) Length = 832 Score = 84.3 bits (207), Expect = 2e-15 Identities = 74/256 (28%), Positives = 105/256 (41%), Gaps = 1/256 (0%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA++GD R LLE N + F GR +P+H A G IV +LL GV+++L+ Sbjct: 559 AAQNGDESSTRLLLEKNASVNEVD-FEGR-TPMHVACQHGQENIVRILLRRGVDVSLQGK 616 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 L A GH +V+ L L+G T +H AA GH R R+++ Sbjct: 617 DAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILI---- 672 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 L VN + TPLH+AA GH +LLL Sbjct: 673 --------------------------DLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLH 706 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL- 1161 GA +T G T LH AA G+ +LL+ A++ A+ T L Sbjct: 707 RGAGKEAMT----------SDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALH 756 Query: 1162 MVAHSWHRNSIEEILS 1209 + A H +EE++S Sbjct: 757 LAAAHGHSEVVEELVS 772 Score = 75.9 bits (185), Expect = 6e-13 Identities = 60/213 (28%), Positives = 92/213 (43%), Gaps = 3/213 (1%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH+AA G LLLE +N ++ G+T + ACQ+G +V+ L+ ++ Sbjct: 556 LHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVS--- 612 Query: 721 YLNGGTA---IHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 L G A +H+AA GH ++L+ P + Sbjct: 613 -LQGKDAWLPLHYAAWQGHLPIVKLLAKQ--PGV-------------------------- 643 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYA 1071 VN + G TPLH+AA GH ++L+DL + V+ ++ TPLH A Sbjct: 644 -SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSL----------LAQTPLHVA 692 Query: 1072 ACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 A G+ +LL+ RGA A + G T L +A Sbjct: 693 AETGHTSTARLLLHRGAGKEAMTSDGYTALHLA 725 Score = 68.2 bits (165), Expect = 1e-10 Identities = 73/282 (25%), Positives = 111/282 (39%), Gaps = 1/282 (0%) Frame = +1 Query: 424 SGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGV 603 SG L+ A + +E L N S G ++PLH A + +V LLL + Sbjct: 485 SGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRG-STPLHMAVERRVRGVVELLLARKI 543 Query: 604 EINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLR 783 +N ++ TAL A Q G + L+ NA+++ D+ G T +H A HG +R Sbjct: 544 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDF-EGRTPMHVACQHGQENIVR 602 Query: 784 LVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVE 963 ++L V V+ + PLH AA GH+ Sbjct: 603 ILLRRGVD------------------------------VSLQGKDAWLPLHYAAWQGHLP 632 Query: 964 CVQLLLDL-GASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKN 1140 V+LL G SV+ T++ G TPLH AA G+ ++LI +++ + Sbjct: 633 IVKLLAKQPGVSVNAQTLD----------GRTPLHLAAQRGHYRVARILIDLCSDVNVCS 682 Query: 1141 ASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPYLCLPL 1266 TPL VA S +L + G+ Y L L Sbjct: 683 LLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHL 724 Score = 67.0 bits (162), Expect = 3e-10 Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 9/195 (4%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G L + L + T GR +PLH AA +GH+ + +L++ ++N+ + Sbjct: 625 AAWQGHLPIVKLLAKQPGVSVNAQTLDGR-TPLHLAAQRGHYRVARILIDLCSDVNVCSL 683 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL---A 795 QT L A + GH + L+L +G TA+H AA +GH ++L++ A Sbjct: 684 LAQTPLHVAAETGHTSTAR-LLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKA 742 Query: 796 DYVPSIPNFLNQT------KHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGH 957 D + P LNQT H SE V + D +++ + GL+ LH+AA H Sbjct: 743 DVLARGP--LNQTALHLAAAHGHSEVVEELVSAD-----VIDLFDEQGLSALHLAAQGRH 795 Query: 958 VECVQLLLDLGASVS 1002 + V+ LL GA ++ Sbjct: 796 AQTVETLLRHGAHIN 810
>Q07DW4:CTTB2_MUNRE Cortactin-binding protein 2 - Muntiacus reevesi (Reeve's muntjac)| (Chinese muntjac) Length = 1642 Score = 84.3 bits (207), Expect = 2e-15 Identities = 65/196 (33%), Positives = 96/196 (48%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 702 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 761 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH +C+ L++A DA+ Sbjct: 762 QVNVAD-TNGFTPLCAAAAQGHFKCVELLIA---------------------YDAN---- 795 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G S T + G TP+ Sbjct: 796 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRD----------GWTPI 840 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 841 HAAVDTGNVDSLKLLM 856 Score = 66.2 bits (160), Expect = 5e-10 Identities = 57/198 (28%), Positives = 90/198 (45%), Gaps = 7/198 (3%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ T G +PL AAAQGH + V L Sbjct: 731 NYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNVADTNGF--TPLCAAAAQGHFKCVEL 788 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT-DYLNGGTAIHFAALH 762 L+ IN GQT L AC+ G+ E ++ +L A R+ +G T IH A Sbjct: 789 LIAYDANINHAADGGQTPLYLACKNGNKECIK--LLLEAGTDRSVKTRDGWTPIHAAVDT 846 Query: 763 GHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK------MVNWKADGGL 924 G+ L+L++ P+ N L + + ++ + +G K ++N G Sbjct: 847 GNVDSLKLLMYHRAPAHGNKLREEPGLAIFDLDQEEERHEGTSKPVVPADLINHADSEGW 906 Query: 925 TPLHMAALNGHVECVQLL 978 T H+AA G C+++L Sbjct: 907 TAAHIAASKGFKNCLEVL 924 Score = 62.4 bits (150), Expect = 7e-09 Identities = 67/255 (26%), Positives = 108/255 (42%), Gaps = 27/255 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N+ Sbjct: 707 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLNAEAQVNV 765 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH++ V+ L+ ++ANI H D G T ++ A +G+ C++L+L Sbjct: 766 ADTNGFTPLCAAAAQGHFKCVELLIAYDANINHAAD--GGQTPLYLACKNGNKECIKLLL 823 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G TP+H A G+V+ ++ Sbjct: 824 ----------------------------EAGTDRSV--KTRDGWTPIHAAVDTGNVDSLK 853 Query: 973 LLL-------------DLGASVSEVTIE----DGTT-----IDLL----GSGSTPLHYAA 1074 LL+ + G ++ ++ E +GT+ DL+ G T H AA Sbjct: 854 LLMYHRAPAHGNKLREEPGLAIFDLDQEEERHEGTSKPVVPADLINHADSEGWTAAHIAA 913 Query: 1075 CGGNAVCCQLLIARG 1119 G C ++L G Sbjct: 914 SKGFKNCLEVLCRHG 928 Score = 57.8 bits (138), Expect = 2e-07 Identities = 40/119 (33%), Positives = 61/119 (51%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL+ A Sbjct: 704 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 761 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 +V + D +G TPL AA G+ C +LLIA AN+ G TPL +A Sbjct: 762 ---QVNVAD-------TNGFTPLCAAAAQGHFKCVELLIAYDANINHAADGGQTPLYLA 810
>Q108T9:CTTB2_LOXAF Cortactin-binding protein 2 - Loxodonta africana (African elephant)| Length = 1661 Score = 84.3 bits (207), Expect = 2e-15 Identities = 64/196 (32%), Positives = 97/196 (49%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 707 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 766 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH +C+ L++A +R++ Sbjct: 767 QVNAADK-NGFTPLCAAAAQGHDKCVELLIA--------------YRAN----------- 800 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G S T + G TP+ Sbjct: 801 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRD----------GWTPV 845 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 846 HAAVDTGNVDSLKLLM 861 Score = 66.6 bits (161), Expect = 4e-10 Identities = 61/205 (29%), Positives = 94/205 (45%), Gaps = 10/205 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH + V L Sbjct: 736 NYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGF--TPLCAAAAQGHDKCVEL 793 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT-DYLNGGTAIHFAALH 762 L+ IN GQT L AC+ G+ E ++ +L A R+ +G T +H A Sbjct: 794 LIAYRANINHAADGGQTPLYLACKNGNKECIK--LLLEAGTDRSVKTRDGWTPVHAAVDT 851 Query: 763 GHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD---GLVK------MVNWKAD 915 G+ L+L++ P+ + LN+ + S +V D D + G VK ++N Sbjct: 852 GNVDSLKLLMYHRAPACGDRLNEEEPES--DVFDLDGGGERPEGTVKPVVPADLINHADR 909 Query: 916 GGLTPLHMAALNGHVECVQLLLDLG 990 G T H+AA G C+++L G Sbjct: 910 EGWTAAHIAASKGFKNCLEILCQHG 934 Score = 62.8 bits (151), Expect = 6e-09 Identities = 68/256 (26%), Positives = 100/256 (39%), Gaps = 28/256 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 712 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLNAEAQVNA 770 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH + V+ L+ + ANI H D G T ++ A +G+ C++L+L Sbjct: 771 ADKNGFTPLCAAAAQGHDKCVELLIAYRANINHAAD--GGQTPLYLACKNGNKECIKLLL 828 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G TP+H A G+V+ ++ Sbjct: 829 ----------------------------EAGTDRSV--KTRDGWTPVHAAVDTGNVDSLK 858 Query: 973 LL-----------------------LDLGASVSEVTIEDGTTIDLLG----SGSTPLHYA 1071 LL LD G E T++ DL+ G T H A Sbjct: 859 LLMYHRAPACGDRLNEEEPESDVFDLDGGGERPEGTVKPVVPADLINHADREGWTAAHIA 918 Query: 1072 ACGGNAVCCQLLIARG 1119 A G C ++L G Sbjct: 919 ASKGFKNCLEILCQHG 934 Score = 57.4 bits (137), Expect = 2e-07 Identities = 39/119 (32%), Positives = 59/119 (49%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL+ A Sbjct: 709 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 766 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 V+ +G TPL AA G+ C +LLIA AN+ G TPL +A Sbjct: 767 QVNAAD----------KNGFTPLCAAAAQGHDKCVELLIAYRANINHAADGGQTPLYLA 815
>Q2QLA2:CTTB2_HORSE Cortactin-binding protein 2 - Equus caballus (Horse)| Length = 1665 Score = 84.3 bits (207), Expect = 2e-15 Identities = 69/215 (32%), Positives = 104/215 (48%), Gaps = 6/215 (2%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 710 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 769 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 + D NG T + AA GH +C++L++A DA+ Sbjct: 770 QVDAAD-KNGFTPLCAAAAQGHFKCVQLLIA---------------------YDAN---- 803 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G+ S T + G TP+ Sbjct: 804 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGSDRSIKTRD----------GWTPV 848 Query: 1063 HYAACGGNAVCCQLLI-----ARGANLAAKNASGS 1152 H A GN +LL+ A G++L + S Sbjct: 849 HAAVDTGNVDSLKLLMYHRAPAHGSSLHKEEPESS 883 Score = 62.0 bits (149), Expect = 1e-08 Identities = 69/257 (26%), Positives = 101/257 (39%), Gaps = 29/257 (11%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + +++ Sbjct: 715 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLNAEAQVDA 773 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH++ VQ L+ ++ANI H D G T ++ A +G+ C++L+L Sbjct: 774 ADKNGFTPLCAAAAQGHFKCVQLLIAYDANINHAAD--GGQTPLYLACKNGNKECIKLLL 831 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 E SD K G TP+H A G+V+ ++ Sbjct: 832 -------------------EAGSDRSI-----------KTRDGWTPVHAAVDTGNVDSLK 861 Query: 973 LLL---------------------DL---GASVSEVTIEDGTTIDLLG----SGSTPLHY 1068 LL+ DL G E T + DL+ G T H Sbjct: 862 LLMYHRAPAHGSSLHKEEPESSIFDLDRQGEESPEGTFKPVVPADLINQADREGWTAAHI 921 Query: 1069 AACGGNAVCCQLLIARG 1119 AA G C ++L G Sbjct: 922 AASKGFKNCLEILCRHG 938 Score = 58.5 bits (140), Expect = 1e-07 Identities = 40/119 (33%), Positives = 58/119 (48%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL+ A Sbjct: 712 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 769 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 V +G TPL AA G+ C QLLIA AN+ G TPL +A Sbjct: 770 QVDAAD----------KNGFTPLCAAAAQGHFKCVQLLIAYDANINHAADGGQTPLYLA 818
>Q8VBX0:ASB13_MOUSE Ankyrin repeat and SOCS box protein 13 - Mus musculus (Mouse)| Length = 278 Score = 84.3 bits (207), Expect = 2e-15 Identities = 59/208 (28%), Positives = 96/208 (46%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH A+ QG + V LLL +G +++ RN G T L AC G E V+ L+ + A ++ Sbjct: 54 TPLHAASLQGQAQCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNP 113 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 Y + +H A + G + C+RL++ ++ E D F Sbjct: 114 PLYT--ASPLHEACMSGSSECVRLLI--------------DVGANLEAHDCHFG------ 151 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 TPLH+A H++CV++LL+ GA+V+ + + T LH+AA Sbjct: 152 ----------TPLHVACAREHLDCVKVLLNAGANVNAAKLHE-----------TALHHAA 190 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTP 1158 N ++LI G N+ A++ G P Sbjct: 191 KVKNVDLIEMLIEFGGNIYARDNRGKKP 218 Score = 62.8 bits (151), Expect = 6e-09 Identities = 45/127 (35%), Positives = 58/127 (45%), Gaps = 22/127 (17%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTI-DLLGSGS------- 1053 VN +TPLH A+L G +CVQLLL GA V I+ T + D SGS Sbjct: 45 VNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLL 104 Query: 1054 --------------TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS 1191 +PLH A G++ C +LLI GANL A + TPL VA + Sbjct: 105 LSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLD 164 Query: 1192 IEEILSN 1212 ++L N Sbjct: 165 CVKVLLN 171 Score = 61.6 bits (148), Expect = 1e-08 Identities = 35/79 (44%), Positives = 46/79 (58%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 TP+H AA G +Q L+D GA V++VT++ TPLH A+ G A C QL Sbjct: 21 TPVHEAAQRGESLQLQQLIDSGACVNQVTVDS----------ITPLHAASLQGQAQCVQL 70 Query: 1105 LIARGANLAAKNASGSTPL 1161 L+A GA + A+N GSTPL Sbjct: 71 LLAAGAQVDARNIDGSTPL 89 Score = 45.8 bits (107), Expect = 7e-04 Identities = 37/119 (31%), Positives = 58/119 (48%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L +A+ G Q + LL ++ + G ++PL A A G E V LLL G ++N Sbjct: 56 LHAASLQGQAQCVQLLLAAGAQVDARNIDG--STPLCDACASGSIECVKLLLSYGAKVNP 113 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 Y + L +AC G E V+ L+ AN+ D + GT +H A H C++++L Sbjct: 114 PLYTA-SPLHEACMSGSSECVRLLIDVGANLEAHD-CHFGTPLHVACAREHLDCVKVLL 170 Score = 42.4 bits (98), Expect = 0.008 Identities = 27/95 (28%), Positives = 46/95 (48%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L A G + R L++ L + G +PLH A A+ H + V +LL +G +N Sbjct: 121 LHEACMSGSSECVRLLIDVGANLEAHDCHFG--TPLHVACAREHLDCVKVLLNAGANVNA 178 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 +TAL A + + ++++ L+ F NI+ D Sbjct: 179 AKLH-ETALHHAAKVKNVDLIEMLIEFGGNIYARD 212
>Q6B858:FANK1_BOVIN Fibronectin type 3 and ankyrin repeat domains protein 1 - Bos taurus| (Bovine) Length = 345 Score = 84.0 bits (206), Expect = 2e-15 Identities = 69/232 (29%), Positives = 106/232 (45%), Gaps = 1/232 (0%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 L AA +G+ +V +L+ G ++NL+N G+ +LM AC GH +VV+ L A+ D Sbjct: 148 LMVAAQRGYTRLVKILISHGTDVNLQNGSGKDSLMLACYAGHLDVVKYLRRHGASWDTRD 207 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 L G TA+H+AA GH + ++ D EV D Sbjct: 208 -LGGCTALHWAADGGHCNVIEWMIGDGC----------------EVDAVD---------- 240 Query: 901 NWKADGGLTPL-HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 A TPL ++A++G+ E LL+D GA +V ++D G TPL A Sbjct: 241 ---AGSRWTPLMRVSAVSGNQEVASLLIDAGA---DVNVKDK-------DGKTPLMVAVL 287 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIR 1233 + QLL+ RGA+ + KN G L +A + R ++ +L Q+R Sbjct: 288 NNHEELVQLLLDRGADASVKNEFGKGVLEMARVFDRQNVLSLLEERKRKQMR 339 Score = 52.4 bits (124), Expect = 8e-06 Identities = 56/203 (27%), Positives = 82/203 (40%), Gaps = 1/203 (0%) Frame = +1 Query: 397 VGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEI 576 V N FG +A L+ AA+ G + + L+ + + + G L A GH ++ Sbjct: 139 VPNKFGFTA----LMVAAQRGYTRLVKILISHGTDVNLQN--GSGKDSLMLACYAGHLDV 192 Query: 577 VSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAI-HFA 753 V L G + R+ G TAL A GH V++ ++ + D + T + + Sbjct: 193 VKYLRRHGASWDTRDLGGCTALHWAADGGHCNVIEWMIGDGCEVDAVDAGSRWTPLMRVS 252 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 A+ G+ L++ DA D VN K G TPL Sbjct: 253 AVSGNQEVASLLI-----------------------DAGAD-------VNVKDKDGKTPL 282 Query: 934 HMAALNGHVECVQLLLDLGASVS 1002 +A LN H E VQLLLD GA S Sbjct: 283 MVAVLNNHEELVQLLLDRGADAS 305
>Q8WZ74:CTTB2_HUMAN Cortactin-binding protein 2 - Homo sapiens (Human)| Length = 1663 Score = 84.0 bits (206), Expect = 2e-15 Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 768 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH C+ L+++ DA+ Sbjct: 769 QVNAADK-NGFTPLCAAAAQGHFECVELLIS---------------------YDAN---- 802 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G + S T + G TP+ Sbjct: 803 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTD----------GWTPV 847 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 848 HAAVDTGNVDSLKLLM 863 Score = 73.6 bits (179), Expect = 3e-12 Identities = 59/200 (29%), Positives = 94/200 (47%), Gaps = 9/200 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGF--TPLCAAAAQGHFECVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML--FNANIHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ G+ E ++ L+ N ++ TD G T +H A Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTD---GWTPVHAAVD 852 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSE-EVSDADFDDDGLVK------MVNWKADG 918 G+ L+L++ +P+ N N+ + SS ++ + +G+ K ++N Sbjct: 853 TGNVDSLKLLMYHRIPAHGNSFNEEESESSVFDLDGGEESPEGISKPVVPADLINHANRE 912 Query: 919 GLTPLHMAALNGHVECVQLL 978 G T H+AA G C+++L Sbjct: 913 GWTAAHIAASKGFKNCLEIL 932
>Q2IBF7:CTTB2_GORGO Cortactin-binding protein 2 - Gorilla gorilla gorilla (Lowland| gorilla) Length = 1663 Score = 84.0 bits (206), Expect = 2e-15 Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 768 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH C+ L+++ DA+ Sbjct: 769 QVNAADK-NGFTPLCAAAAQGHFECVELLIS---------------------YDAN---- 802 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G + S T + G TP+ Sbjct: 803 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTD----------GWTPV 847 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 848 HAAVDTGNVDSLKLLM 863 Score = 73.9 bits (180), Expect = 2e-12 Identities = 59/200 (29%), Positives = 94/200 (47%), Gaps = 9/200 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGF--TPLCAAAAQGHFECVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML--FNANIHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ G+ E ++ L+ N ++ TD G T +H A Sbjct: 796 LISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTD---GWTPVHAAVD 852 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSE-EVSDADFDDDGLVK------MVNWKADG 918 G+ L+L++ +P+ N N+ + SS ++ + +G+ K ++N Sbjct: 853 TGNVDSLKLLMYHRIPAHGNSFNEEESESSVFDLDGGEESPEGICKPVVPADLINHANRE 912 Query: 919 GLTPLHMAALNGHVECVQLL 978 G T H+AA G C+++L Sbjct: 913 GWTAAHIAASKGFKNCLEIL 932
>Q00PJ1:CTTB2_ATEAB Cortactin-binding protein 2 - Atelerix albiventris (Middle-African| hedgehog) Length = 1654 Score = 84.0 bits (206), Expect = 2e-15 Identities = 65/196 (33%), Positives = 97/196 (49%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 710 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAQA 769 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH +C+ L++A +DA+ Sbjct: 770 QVNAADK-NGFTPLCAAAAQGHFKCIELLIA---------------------NDAN---- 803 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL G+ S T + G TP+ Sbjct: 804 -----INHAADGGQTPLYLACKNGNNECIKLLLGAGSDRSVKTRD----------GWTPV 848 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 849 HAAVDTGNVDNLKLLM 864 Score = 65.9 bits (159), Expect = 7e-10 Identities = 57/200 (28%), Positives = 93/200 (46%), Gaps = 9/200 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH + + L Sbjct: 739 NYSCEDGHSALYSAAKNGHTDCVRLLLNAQAQVNAADKNGF--TPLCAAAAQGHFKCIEL 796 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHG 765 L+ + IN GQT L AC+ G+ E ++ L+L + +G T +H A G Sbjct: 797 LIANDANINHAADGGQTPLYLACKNGNNECIK-LLLGAGSDRSVKTRDGWTPVHAAVDTG 855 Query: 766 HARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD---GLVK------MVNWKADG 918 + L+L++ P N N+ K S+ + D D +++ G+ K ++N Sbjct: 856 NVDNLKLLMYYEAPIPGNSFNEEKLESN--IIDLDQEEESPEGIPKTVVPADLINHADRE 913 Query: 919 GLTPLHMAALNGHVECVQLL 978 G T H+AA G C+++L Sbjct: 914 GWTAAHIAASKGFKNCLEIL 933 Score = 58.5 bits (140), Expect = 1e-07 Identities = 39/119 (32%), Positives = 59/119 (49%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL+ A Sbjct: 712 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLNAQA 769 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 V+ +G TPL AA G+ C +LLIA AN+ G TPL +A Sbjct: 770 QVNAAD----------KNGFTPLCAAAAQGHFKCIELLIANDANINHAADGGQTPLYLA 818
>Q8HXA6:ASB15_BOVIN Ankyrin repeat and SOCS box protein 15 - Bos taurus (Bovine)| Length = 588 Score = 84.0 bits (206), Expect = 2e-15 Identities = 69/233 (29%), Positives = 119/233 (51%), Gaps = 3/233 (1%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L+ A + G ALL++N L + R S +H AA QGH +I++LLL +G ++L Sbjct: 148 LLLAIKRGSYDMVSALLKHNTSLDQPCV--KRWSAMHEAAKQGHKDIIALLLNNGGNVHL 205 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ G T L A +YGH +V++ L+ ++ +G + + AA G+ C+ L+L Sbjct: 206 KDGFGVTPLGVAAEYGHCDVLEHLIHKGGDVLALAD-DGASVLFEAAGGGNPDCISLLL- 263 Query: 796 DYVPS--IPNFLNQTK-HRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVEC 966 +Y S IPN HR++ E V + GLTP+H AA + +C Sbjct: 264 EYGGSGNIPNRAGHLPIHRAAYEGHYLALKYLIPVTSKHAIQKSGLTPIHSAADGQNAQC 323 Query: 967 VQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGAN 1125 ++LL++ G V+ + + D + T L++A C + +C ++L+A GA+ Sbjct: 324 LELLIENGFDVNSL-LADHISESYDDERKTALYFAVCNNDILCTEILLAAGAD 375 Score = 64.7 bits (156), Expect = 1e-09 Identities = 58/209 (27%), Positives = 92/209 (44%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PL A G E V LLE GV N +N +G+T L+ A + G +++V L+ N ++ + Sbjct: 113 TPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLLAIKRGSYDMVSALLKHNTSLDQ 172 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + +A+H AA GH + L+L ++ G V Sbjct: 173 -PCVKRWSAMHEAAKQGHKDIIALLL---------------------------NNGGNVH 204 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 + K G+TPL +AA GH + ++ L+ G G + L G++ L AA Sbjct: 205 L---KDGFGVTPLGVAAEYGHCDVLEHLIHKG----------GDVLALADDGASVLFEAA 251 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL 1161 GGN C LL+ G + N +G P+ Sbjct: 252 GGGNPDCISLLLEYGGSGNIPNRAGHLPI 280 Score = 34.3 bits (77), Expect = 2.2 Identities = 27/84 (32%), Positives = 39/84 (46%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 G PLH A V+ +Q +L++ S T+ + T D G TPL A G Sbjct: 76 GWFPLHEAV----VQPIQQILEVVLDASYKTLWEFKTSD----GETPLTLAVKAGLVENV 127 Query: 1099 QLLIARGANLAAKNASGSTPLMVA 1170 + L+ +G KN G TPL++A Sbjct: 128 RTLLEKGVWPNTKNDKGETPLLLA 151
>Q71S21:INVSB_XENLA Inversin-B - Xenopus laevis (African clawed frog)| Length = 1002 Score = 83.6 bits (205), Expect = 3e-15 Identities = 72/236 (30%), Positives = 108/236 (45%), Gaps = 3/236 (1%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN--ANI 708 +PLHYAA + V +LL + + G+TALM A G EVV+T++ N + Sbjct: 287 TPLHYAAQGNCPDTVRVLLSHPSVRDEADLEGRTALMWAAGKGSDEVVRTMLELNPKLEV 346 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 +RTD GGTA+H A+L G +R++L + + + ++ KH Sbjct: 347 NRTDKY-GGTALHAASLSGQITTVRILLENRAQA--DAVDVMKH---------------- 387 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 TPL A GH E + L+ GA V V + G +PLH+ Sbjct: 388 ------------TPLFRACEMGHREVIATLIKGGAKVHLVDKD----------GRSPLHW 425 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLM-VAHSWHRNSIEEILSNEPGGQIR 1233 AA GGNA CQ+LI N A++ G TPL A+ + +E ++ N+ I+ Sbjct: 426 AALGGNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNIQ 481 Score = 82.8 bits (203), Expect = 5e-15 Identities = 73/260 (28%), Positives = 126/260 (48%), Gaps = 10/260 (3%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLA--RYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 L+ AA G + R +LE NP+L R +GG + LH A+ G V +LLE+ + Sbjct: 322 LMWAAGKGSDEVVRTMLELNPKLEVNRTDKYGG--TALHAASLSGQITTVRILLENRAQA 379 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 + + T L +AC+ GH EV+ TL+ A +H D +G + +H+AAL G+A +++ Sbjct: 380 DAVDVMKHTPLFRACEMGHREVIATLIKGGAKVHLVD-KDGRSPLHWAALGGNANVCQIL 438 Query: 790 LADYV-PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKAD------GGLTPLHMAAL 948 + + + P ++ +T + + + + V M N KAD G T LH + Sbjct: 439 IENNINPDAQDYEGRTPLQCA---AYGGYIGCMEVLMEN-KADPNIQDKNGRTALHWSCN 494 Query: 949 NGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGA-N 1125 NG+++ V+LLL A +++ + TPL YA GG+ Q ++ GA + Sbjct: 495 NGYLDAVKLLLGYNAFPNQMENTE--------ERYTPLDYALLGGHQEVIQFMLEHGALS 546 Query: 1126 LAAKNASGSTPLMVAHSWHR 1185 +AA + + + H+ Sbjct: 547 IAAIQDIAAFKIQAVYKGHK 566 Score = 61.2 bits (147), Expect = 2e-08 Identities = 74/313 (23%), Positives = 123/313 (39%), Gaps = 46/313 (14%) Frame = +1 Query: 418 SASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLES 597 S+ + +AA GD L+ +P++ GR +PL Y+ LL+ Sbjct: 8 SSLASPIQAAAVTGDKTTLLRLIASSPQVIDQEDQLGR-TPLMYSVLGDRRSCAEALLKH 66 Query: 598 GVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARC 777 G ++N + G+TAL A Q G+ +++ L+ A+ D L TA+H + H +C Sbjct: 67 GAKVNRPDRSGRTALHLAAQTGNHRLLKLLLSRKADCTHRD-LCDITALHLSTRHQDTQC 125 Query: 778 LRLVLADYVPSIPNFLNQTK---------------------HRSSEEVSDAD-------- 870 L L+L P + +Q K H S+ + D + Sbjct: 126 LVLLLKYTPPGQVDAQDQRKQTALHWSAYYNRPQHVRLLVRHGSNIGIPDTEGKIPLHWA 185 Query: 871 ---------------FDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDL-GASVS 1002 F+ ++NW+ G TPLH+A +G+ E V+LL G +V+ Sbjct: 186 AGHKDPEAALTVRCLFEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLLTSYRGCNVA 245 Query: 1003 EVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIAR-GANLAAKNASGSTPLMVAHSW 1179 TPLH+AA G+ LL+ R + ++ G+TPL A Sbjct: 246 PYD----------NLFRTPLHWAALLGHTPIAHLLLERNNSPNIPSDSQGATPLHYAAQG 295 Query: 1180 HRNSIEEILSNEP 1218 + +L + P Sbjct: 296 NCPDTVRVLLSHP 308 Score = 48.1 bits (113), Expect = 1e-04 Identities = 67/279 (24%), Positives = 109/279 (39%), Gaps = 46/279 (16%) Frame = +1 Query: 472 ARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE--------------- 606 A ALL++ ++ R G + LH AA G+H ++ LLL + Sbjct: 60 AEALLKHGAKVNRPDRSG--RTALHLAAQTGNHRLLKLLLSRKADCTHRDLCDITALHLS 117 Query: 607 --------------------INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYL 726 ++ ++ R QTAL + Y + V+ L+ +NI D Sbjct: 118 TRHQDTQCLVLLLKYTPPGQVDAQDQRKQTALHWSAYYNRPQHVRLLVRHGSNIGIPD-T 176 Query: 727 NGGTAIHFAALHGHARCLRLV--LADYVPSIPNFLNQTKH--RSSEEVSDADFDDDGLVK 894 G +H+AA H V L + P+ + LN + R+ ++ D + + + Sbjct: 177 EGKIPLHWAAGHKDPEAALTVRCLFEAAPT-ESLLNWQDYEGRTPLHLAVGDGNQEVVRL 235 Query: 895 MVNWKADGGL-------TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS 1053 + +++ TPLH AAL GH LLL+ S I G+ Sbjct: 236 LTSYRGCNVAPYDNLFRTPLHWAALLGHTPIAHLLLERNNS---------PNIPSDSQGA 286 Query: 1054 TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 TPLHYAA G ++L++ + + G T LM A Sbjct: 287 TPLHYAAQGNCPDTVRVLLSHPSVRDEADLEGRTALMWA 325
>Q8TC84:FANK1_HUMAN Fibronectin type 3 and ankyrin repeat domains protein 1 - Homo| sapiens (Human) Length = 345 Score = 83.6 bits (205), Expect = 3e-15 Identities = 66/223 (29%), Positives = 106/223 (47%), Gaps = 1/223 (0%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 L AA +G+ +V +L+ +G ++NL+N G+ +LM AC GH +VV+ L A+ D Sbjct: 148 LMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQARD 207 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 L G TA+H+AA GH + ++ D + D D G Sbjct: 208 -LGGCTALHWAADGGHCSVIEWMIKDGC-------------------EVDVVDTG----- 242 Query: 901 NWKADGGLTPL-HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 G TPL ++A++G+ LL+D GA+V+ ++D +G TPL A Sbjct: 243 -----SGWTPLMRVSAVSGNQRVASLLIDAGANVN---VKDR-------NGKTPLMVAVL 287 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 + QLL+ +GA+ + KN G L +A + R S+ +L Sbjct: 288 NNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVVSLL 330 Score = 69.3 bits (168), Expect = 6e-11 Identities = 68/233 (29%), Positives = 108/233 (46%), Gaps = 5/233 (2%) Frame = +1 Query: 487 EYNPRLARYSTFGGRNSP-LHYAAAQGHHEIVSLLLESG-VEINLRNYRGQTALMQACQY 660 EY+P ++ +T +S LH A + +++ +L+ G V++++ N G TALM A Q Sbjct: 95 EYSPLVSVSTTREPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQK 154 Query: 661 GHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKH 840 G+ +V+ L+ +++ + +G ++ A GH ++ + +H Sbjct: 155 GYTRLVKILVSNGTDVNLKNG-SGKDSLMLACYAGHLDVVKYL--------------RRH 199 Query: 841 RSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIED 1020 +S + D GG T LH AA GH SV E I+D Sbjct: 200 GASWQARDL----------------GGCTALHWAADGGH-----------CSVIEWMIKD 232 Query: 1021 GTTIDLL--GSGSTPL-HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G +D++ GSG TPL +A GN LLI GAN+ K+ +G TPLMVA Sbjct: 233 GCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVA 285 Score = 40.4 bits (93), Expect = 0.030 Identities = 19/58 (32%), Positives = 33/58 (56%) Frame = +1 Query: 517 TFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLM 690 T G + +A G+ + SLL+++G +N+++ G+T LM A H E+VQ L+ Sbjct: 241 TGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLL 298 Score = 33.1 bits (74), Expect = 4.8 Identities = 17/51 (33%), Positives = 26/51 (50%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTL 687 +PL A H E+V LLL+ G + +++N G+ L A + VV L Sbjct: 280 TPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVVSLL 330
>Q2QL82:CTTB2_MICMU Cortactin-binding protein 2 - Microcebus murinus (Lesser mouse lemur)| Length = 1647 Score = 83.6 bits (205), Expect = 3e-15 Identities = 65/196 (33%), Positives = 95/196 (48%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 695 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 754 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH C+ L++A DA+ Sbjct: 755 QVNAAD-KNGFTPLCAAAAQGHFECVELLIA---------------------YDAN---- 788 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G S T + G TP+ Sbjct: 789 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRD----------GWTPV 833 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 834 HAAVDTGNVDSLKLLM 849 Score = 71.2 bits (173), Expect = 2e-11 Identities = 59/199 (29%), Positives = 92/199 (46%), Gaps = 8/199 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 724 NYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGF--TPLCAAAAQGHFECVEL 781 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT-DYLNGGTAIHFAALH 762 L+ IN GQT L AC+ G+ E ++ +L A R+ +G T +H A Sbjct: 782 LIAYDANINHAADGGQTPLYLACKNGNKECIK--LLLEAGTDRSVKTRDGWTPVHAAVDT 839 Query: 763 GHARCLRLVLADYVPSIPNFLNQTKHRSS-EEVSDADFDDDGLVK------MVNWKADGG 921 G+ L+L++ P+ N LN+ + S ++ D + +G K ++N G Sbjct: 840 GNVDSLKLLMYHRAPAHGNSLNEEEPESDVSDLDDGEESSEGESKPVVPADLINHADREG 899 Query: 922 LTPLHMAALNGHVECVQLL 978 T H+AA G C+++L Sbjct: 900 WTAAHIAASKGFKNCLEIL 918 Score = 57.8 bits (138), Expect = 2e-07 Identities = 39/119 (32%), Positives = 59/119 (49%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL+ A Sbjct: 697 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 754 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 V+ +G TPL AA G+ C +LLIA AN+ G TPL +A Sbjct: 755 QVNAAD----------KNGFTPLCAAAAQGHFECVELLIAYDANINHAADGGQTPLYLA 803
>Q8WXK3:ASB13_HUMAN Ankyrin repeat and SOCS box protein 13 - Homo sapiens (Human)| Length = 278 Score = 83.6 bits (205), Expect = 3e-15 Identities = 59/208 (28%), Positives = 95/208 (45%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH A+ QG V LLL +G +++ RN G T L AC G E V+ L+ + A ++ Sbjct: 54 TPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNP 113 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 Y + +H A + G + C+RL++ ++ E D F Sbjct: 114 PLYT--ASPLHEACMSGSSECVRLLI--------------DVGANLEAHDCHFG------ 151 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 TPLH+A H++CV++LL+ GA+V+ + + T LH+AA Sbjct: 152 ----------TPLHVACAREHLDCVKVLLNAGANVNAAKLHE-----------TALHHAA 190 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTP 1158 N ++LI G N+ A++ G P Sbjct: 191 KVKNVDLIEMLIEFGGNIYARDNRGKKP 218 Score = 62.0 bits (149), Expect = 1e-08 Identities = 45/127 (35%), Positives = 57/127 (44%), Gaps = 22/127 (17%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTI-DLLGSGS------- 1053 VN +TPLH A+L G CVQLLL GA V I+ T + D SGS Sbjct: 45 VNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLL 104 Query: 1054 --------------TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS 1191 +PLH A G++ C +LLI GANL A + TPL VA + Sbjct: 105 LSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLD 164 Query: 1192 IEEILSN 1212 ++L N Sbjct: 165 CVKVLLN 171 Score = 59.7 bits (143), Expect = 5e-08 Identities = 34/79 (43%), Positives = 46/79 (58%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 TP+H AA G +Q L++ GA V++VT++ TPLH A+ G A C QL Sbjct: 21 TPVHEAAQRGESLQLQQLIESGACVNQVTVDS----------ITPLHAASLQGQARCVQL 70 Query: 1105 LIARGANLAAKNASGSTPL 1161 L+A GA + A+N GSTPL Sbjct: 71 LLAAGAQVDARNIDGSTPL 89 Score = 45.1 bits (105), Expect = 0.001 Identities = 30/87 (34%), Positives = 45/87 (51%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 ++PL A A G E V LLL G ++N Y + L +AC G E V+ L+ AN+ Sbjct: 86 STPLCDACASGSIECVKLLLSYGAKVNPPLYTA-SPLHEACMSGSSECVRLLIDVGANLE 144 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVL 792 D + GT +H A H C++++L Sbjct: 145 AHD-CHFGTPLHVACAREHLDCVKVLL 170 Score = 42.4 bits (98), Expect = 0.008 Identities = 27/95 (28%), Positives = 46/95 (48%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L A G + R L++ L + G +PLH A A+ H + V +LL +G +N Sbjct: 121 LHEACMSGSSECVRLLIDVGANLEAHDCHFG--TPLHVACAREHLDCVKVLLNAGANVNA 178 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 +TAL A + + ++++ L+ F NI+ D Sbjct: 179 AKLH-ETALHHAAKVKNVDLIEMLIEFGGNIYARD 212
>Q9H9B1:EHMT1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 - Homo| sapiens (Human) Length = 1267 Score = 83.2 bits (204), Expect = 4e-15 Identities = 71/247 (28%), Positives = 110/247 (44%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 ++L +AR G+LQ+ +L + SPLH AA GH +I +L+++G I Sbjct: 709 KQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANI 768 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 + + +T LM+A + H E V+ L+ A + D G T +H AA GH ++ + Sbjct: 769 DTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD-AEGSTCLHLAAKKGHYEVVQYL 827 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 L S+ D VN + DGG TP+ A HV+ V Sbjct: 828 L----------------------SNGQMD-------VNCQDDGGWTPMIWATEYKHVDLV 858 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 +LLL G S++ I D + LH+AA G ++L+A +L A N G Sbjct: 859 KLLLSKG---SDINIRD-------NEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHG 908 Query: 1150 STPLMVA 1170 +PL +A Sbjct: 909 DSPLHIA 915 Score = 33.1 bits (74), Expect = 4.8 Identities = 23/69 (33%), Positives = 33/69 (47%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G + A LL L + G +SPLH AA + ++ V L L ++ L+N Sbjct: 882 AAFSGCVDIAEILLAAKCDLHAVNIHG--DSPLHIAARENRYDCVVLFLSRDSDVTLKNK 939 Query: 625 RGQTALMQA 651 G+T L A Sbjct: 940 EGETPLQCA 948
>Q9BGT9:ASB7_MACFA Ankyrin repeat and SOCS box protein 7 - Macaca fascicularis (Crab| eating macaque) (Cynomolgus monkey) Length = 318 Score = 83.2 bits (204), Expect = 4e-15 Identities = 69/238 (28%), Positives = 105/238 (44%), Gaps = 29/238 (12%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 A A G V +LE G N R+ G T L + G V+ + A+ D + Sbjct: 21 AVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIG 80 Query: 730 GGTAIHFAALHGHARCLRLVL-ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM--- 897 G TA+H+AA+HG AR RL+L ++Y I N + A + D V++ Sbjct: 81 GFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVA--AHYGRDSFVRLLLE 138 Query: 898 ----VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVS-------------------EV 1008 V+ +D G TPL +A + CV++LLD A++ + Sbjct: 139 FKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQNGFLLRYAVIKSNHSYCRM 198 Query: 1009 TIEDGTTIDL--LGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHS 1176 ++ G DL L G TPLH +A + +C ++L GA+ +N G TPL V+ S Sbjct: 199 FLQRGADTDLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSIS 256 Score = 50.4 bits (119), Expect = 3e-05 Identities = 44/160 (27%), Positives = 65/160 (40%) Frame = +1 Query: 727 NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNW 906 NG T +HF+A G RC+R+ L +H + V D Sbjct: 46 NGWTLLHFSAARGKERCVRVFL--------------EHGADPTVKDLI------------ 79 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 GG T LH AA++G +L+L+ + + G TPLH AA G Sbjct: 80 ---GGFTALHYAAMHGRARIARLMLESEYRSDIINAKSN-------DGWTPLHVAAHYGR 129 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 +LL+ A + + G+TPL +A R+S +IL Sbjct: 130 DSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKIL 169 Score = 48.5 bits (114), Expect = 1e-04 Identities = 51/198 (25%), Positives = 79/198 (39%), Gaps = 2/198 (1%) Frame = +1 Query: 445 AARDGDLQEARALLE--YNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLR 618 AA G + AR +LE Y + + G +PLH AA G V LLLE E++ Sbjct: 88 AAMHGRARIARLMLESEYRSDIINAKSNDGW-TPLHVAAHYGRDSFVRLLLEFKAEVDPL 146 Query: 619 NYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLAD 798 + +G T L A V+ L+ NANI + G + +A + + R+ L Sbjct: 147 SDKGTTPLQLAIIRERSSCVKILLDHNANID----IQNGFLLRYAVIKSNHSYCRMFL-- 200 Query: 799 YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLL 978 + +D D + + G TPLH++AL V C ++L Sbjct: 201 -----------------QRGADTDLG----------RLEDGQTPLHLSALRDDVLCARML 233 Query: 979 LDLGASVSEVTIEDGTTI 1032 + GA + E T + Sbjct: 234 YNYGADTNTRNYEGQTPL 251
>Q5RCK5:ASB7_PONPY Ankyrin repeat and SOCS box protein 7 - Pongo pygmaeus (Orangutan)| Length = 318 Score = 82.8 bits (203), Expect = 5e-15 Identities = 71/246 (28%), Positives = 108/246 (43%), Gaps = 32/246 (13%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 S + A A G V +LE G N R+ G T L + G V+ + A+ Sbjct: 16 SQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTV 75 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVL-ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 D + G TA+H+AA+HG AR RL+L ++Y I N + A + D V Sbjct: 76 KDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVA--AHYGRDSFV 133 Query: 892 KMV-NWKA------DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDG--------- 1023 +++ +KA D G TPL +A + CV++LLD A++ I++G Sbjct: 134 RLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANID---IQNGFLLRYAVIK 190 Query: 1024 ---------------TTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTP 1158 T + L G TPLH +A + +C ++L GA+ +N G TP Sbjct: 191 SNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTP 250 Query: 1159 LMVAHS 1176 L V+ S Sbjct: 251 LAVSIS 256 Score = 50.4 bits (119), Expect = 3e-05 Identities = 44/160 (27%), Positives = 65/160 (40%) Frame = +1 Query: 727 NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNW 906 NG T +HF+A G RC+R+ L +H + V D Sbjct: 46 NGWTLLHFSAARGKERCVRVFL--------------EHGADPTVKDLI------------ 79 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 GG T LH AA++G +L+L+ + + G TPLH AA G Sbjct: 80 ---GGFTALHYAAMHGRARIARLMLESEYRSDIINAKSN-------DGWTPLHVAAHYGR 129 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 +LL+ A + + G+TPL +A R+S +IL Sbjct: 130 DSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKIL 169
>Q8ZWC4:Y1861_PYRAE Putative ankyrin repeat protein PAE1861 - Pyrobaculum aerophilum| Length = 256 Score = 82.4 bits (202), Expect = 7e-15 Identities = 76/252 (30%), Positives = 119/252 (47%), Gaps = 7/252 (2%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L++AAR G+ + LL +G +PL+YAA +G V LL+++G + N Sbjct: 6 LLNAARRGEAELLTRLLNEGCSPDVQDDYG--RTPLYYAAERGDVGTVDLLIKAGADPNA 63 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 R+ G+T ++ A Q + V+ L + A++ AA +G + +R +LA Sbjct: 64 RDREGKTPIIIATQSRKFGVIPLLSASAVGVEE--------ALYTAARNGCHKAVRYMLA 115 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV-------NWKADGGLTPLHMAALNG 954 V + E + D GLVK++ N + G TPLHMA+ + Sbjct: 116 RGV--------RPGASHGESLLHLVAGDAGLVKLLLEYGVDPNARDAHGKTPLHMASEHN 167 Query: 955 HVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAA 1134 +CV+LLL G +V ++D G+G TPLHYA + C +LL+ GA+L A Sbjct: 168 CAQCVELLLKRG---PDVNVKD-------GAGRTPLHYA---DDVDCIKLLLRYGADLNA 214 Query: 1135 KNASGSTPLMVA 1170 + G TPL A Sbjct: 215 VDNMGRTPLHYA 226 Score = 39.7 bits (91), Expect = 0.051 Identities = 29/90 (32%), Positives = 44/90 (48%) Frame = +1 Query: 940 AALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG 1119 AA G E + LL+ G S ++D G TPL+YAA G+ LLI G Sbjct: 9 AARRGEAELLTRLLNEGCSPD---VQDDY-------GRTPLYYAAERGDVGTVDLLIKAG 58 Query: 1120 ANLAAKNASGSTPLMVAHSWHRNSIEEILS 1209 A+ A++ G TP+++A + + +LS Sbjct: 59 ADPNARDREGKTPIIIATQSRKFGVIPLLS 88
>A0M8S4:CTTB2_PAPAN Cortactin-binding protein 2 - Papio anubis (Olive baboon)| Length = 1663 Score = 82.4 bits (202), Expect = 7e-15 Identities = 65/196 (33%), Positives = 95/196 (48%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 768 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 I+ D NG T + AA GH C+ L++A DA+ Sbjct: 769 QINAAD-KNGFTPLCAAAAQGHFECVELLIA---------------------YDAN---- 802 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A N + EC++LLL+ G + S T + G TP+ Sbjct: 803 -----INHAADGGQTPLYLACKNENKECIKLLLEAGTNRSVKTTD----------GWTPV 847 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 848 HAAVDTGNVDSLKLLM 863 Score = 70.1 bits (170), Expect = 4e-11 Identities = 57/200 (28%), Positives = 92/200 (46%), Gaps = 9/200 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQINAADKNGF--TPLCAAAAQGHFECVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML--FNANIHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ + E ++ L+ N ++ TD G T +H A Sbjct: 796 LIAYDANINHAADGGQTPLYLACKNENKECIKLLLEAGTNRSVKTTD---GWTPVHAAVD 852 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSE-EVSDADFDDDGLVK------MVNWKADG 918 G+ L+L++ +P+ N N+ + S ++ + +G+ K ++N Sbjct: 853 TGNVDSLKLLMYHRIPACGNSFNEEESESGVFDLDGGEESPEGIFKPVVPADLINHANRE 912 Query: 919 GLTPLHMAALNGHVECVQLL 978 G T H+AA G C+++L Sbjct: 913 GWTAAHIAASKGFKNCLEIL 932 Score = 57.0 bits (136), Expect = 3e-07 Identities = 38/119 (31%), Positives = 58/119 (48%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL A Sbjct: 711 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 768 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 ++ +G TPL AA G+ C +LLIA AN+ G TPL +A Sbjct: 769 QINAAD----------KNGFTPLCAAAAQGHFECVELLIAYDANINHAADGGQTPLYLA 817
>Q07DY4:CTTB2_COLGU Cortactin-binding protein 2 - Colobus guereza (Black-and-white| colobus monkey) Length = 1663 Score = 82.4 bits (202), Expect = 7e-15 Identities = 65/196 (33%), Positives = 95/196 (48%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 768 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 I+ D NG T + AA GH C+ L++A DA+ Sbjct: 769 QINAAD-KNGFTPLCAAAAQGHFECVELLIA---------------------YDAN---- 802 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A N + EC++LLL+ G + S T + G TP+ Sbjct: 803 -----INHAADGGQTPLYLACKNENKECIKLLLEAGTNRSVKTTD----------GWTPV 847 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 848 HAAVDTGNVDSLKLLM 863 Score = 70.1 bits (170), Expect = 4e-11 Identities = 57/200 (28%), Positives = 92/200 (46%), Gaps = 9/200 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQINAADKNGF--TPLCAAAAQGHFECVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML--FNANIHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ + E ++ L+ N ++ TD G T +H A Sbjct: 796 LIAYDANINHAADGGQTPLYLACKNENKECIKLLLEAGTNRSVKTTD---GWTPVHAAVD 852 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSE-EVSDADFDDDGLVK------MVNWKADG 918 G+ L+L++ +P+ N N+ + S ++ + +G+ K ++N Sbjct: 853 TGNVDSLKLLMYHRIPACGNSFNEEESESGVFDLDGGEESPEGIFKPVVPADLINHANRE 912 Query: 919 GLTPLHMAALNGHVECVQLL 978 G T H+AA G C+++L Sbjct: 913 GWTAAHIAASKGFKNCLEIL 932 Score = 57.0 bits (136), Expect = 3e-07 Identities = 38/119 (31%), Positives = 58/119 (48%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL A Sbjct: 711 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 768 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 ++ +G TPL AA G+ C +LLIA AN+ G TPL +A Sbjct: 769 QINAAD----------KNGFTPLCAAAAQGHFECVELLIAYDANINHAADGGQTPLYLA 817
>Q2IBA2:CTTB2_CERAE Cortactin-binding protein 2 - Cercopithecus aethiops (Green monkey)| (Grivet) Length = 1662 Score = 82.4 bits (202), Expect = 7e-15 Identities = 65/196 (33%), Positives = 95/196 (48%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 768 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 I+ D NG T + AA GH C+ L++A DA+ Sbjct: 769 QINAAD-KNGFTPLCAAAAQGHFECVELLIA---------------------YDAN---- 802 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A N + EC++LLL+ G + S T + G TP+ Sbjct: 803 -----INHAADGGQTPLYLACKNENKECIKLLLEAGTNRSVKTTD----------GWTPV 847 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 848 HAAVDTGNVDSLKLLM 863 Score = 70.1 bits (170), Expect = 4e-11 Identities = 57/200 (28%), Positives = 92/200 (46%), Gaps = 9/200 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQINAADKNGF--TPLCAAAAQGHFECVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML--FNANIHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ + E ++ L+ N ++ TD G T +H A Sbjct: 796 LIAYDANINHAADGGQTPLYLACKNENKECIKLLLEAGTNRSVKTTD---GWTPVHAAVD 852 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSE-EVSDADFDDDGLVK------MVNWKADG 918 G+ L+L++ +P+ N N+ + S ++ + +G+ K ++N Sbjct: 853 TGNVDSLKLLMYHRIPACGNSFNEEESESGVFDLDGGEESPEGIFKPVVPADLINHANRE 912 Query: 919 GLTPLHMAALNGHVECVQLL 978 G T H+AA G C+++L Sbjct: 913 GWTAAHIAASKGFKNCLEIL 932 Score = 57.0 bits (136), Expect = 3e-07 Identities = 38/119 (31%), Positives = 58/119 (48%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL A Sbjct: 711 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 768 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 ++ +G TPL AA G+ C +LLIA AN+ G TPL +A Sbjct: 769 QINAAD----------KNGFTPLCAAAAQGHFECVELLIAYDANINHAADGGQTPLYLA 817
>Q4X251:AKR1_ASPFU Palmitoyltransferase akr1 - Aspergillus fumigatus (Sartorya fumigata)| Length = 738 Score = 82.0 bits (201), Expect = 9e-15 Identities = 73/249 (29%), Positives = 109/249 (43%), Gaps = 1/249 (0%) Frame = +1 Query: 427 GERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE 606 GE ++ AR G++ + L + A Y G +PLH+AA + + LL++G + Sbjct: 64 GEDIMQIARIGEIGPMQRLFDEKKFTANYQDEEGI-TPLHWAAINNQYAMCKFLLDNGAD 122 Query: 607 INLRNYRG-QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLR 783 +N + T M A Q H+ +V L+ A+ TD + G +H A + G+A L Sbjct: 123 VNAKGGDSVATPAMWAAQRCHYYIVHLLLQHGADPLLTD-VQGYNILHLATIDGNAFLLV 181 Query: 784 LVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVE 963 L+L +P + ++Q H T L AA G+ Sbjct: 182 LLLHQEIPV--DVIDQQGH----------------------------TGLMWAAYKGYPA 211 Query: 964 CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNA 1143 CV L L GA+V+ V +DG G TPLH+A G+ C Q LI GA+ AK Sbjct: 212 CVDLFLRWGANVNAV--DDG--------GLTPLHWALVKGSLPCVQKLIEYGADRFAKTR 261 Query: 1144 SGSTPLMVA 1170 G +P VA Sbjct: 262 DGKSPATVA 270
>Q91ZU0:ASB7_MOUSE Ankyrin repeat and SOCS box protein 7 - Mus musculus (Mouse)| Length = 318 Score = 81.6 bits (200), Expect = 1e-14 Identities = 70/241 (29%), Positives = 106/241 (43%), Gaps = 32/241 (13%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 A A G V +LE G N R+ G T L + G V+ + A+ D + Sbjct: 21 AVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIG 80 Query: 730 GGTAIHFAALHGHARCLRLVL-ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV-N 903 G TA+H+AA+HG AR RL+L ++Y I N + A + D V+++ Sbjct: 81 GFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVA--AHYGRDSFVRLLLE 138 Query: 904 WKA------DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDG-------------- 1023 +KA D G TPL +A + CV++LLD A++ I++G Sbjct: 139 FKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANID---IQNGFLLRYAVIKSNHSY 195 Query: 1024 ----------TTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAH 1173 T + L G TPLH +A + +C ++L GA+ +N G TPL V+ Sbjct: 196 CRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSI 255 Query: 1174 S 1176 S Sbjct: 256 S 256 Score = 50.4 bits (119), Expect = 3e-05 Identities = 44/160 (27%), Positives = 65/160 (40%) Frame = +1 Query: 727 NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNW 906 NG T +HF+A G RC+R+ L +H + V D Sbjct: 46 NGWTLLHFSAARGKERCVRVFL--------------EHGADPTVKDLI------------ 79 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 GG T LH AA++G +L+L+ + + G TPLH AA G Sbjct: 80 ---GGFTALHYAAMHGRARIARLMLESEYRSDIINAKSN-------DGWTPLHVAAHYGR 129 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 +LL+ A + + G+TPL +A R+S +IL Sbjct: 130 DSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKIL 169 Score = 46.6 bits (109), Expect = 4e-04 Identities = 50/198 (25%), Positives = 79/198 (39%), Gaps = 2/198 (1%) Frame = +1 Query: 445 AARDGDLQEARALLE--YNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLR 618 AA G + AR +LE Y + + G +PLH AA G V LLLE E++ Sbjct: 88 AAMHGRARIARLMLESEYRSDIINAKSNDGW-TPLHVAAHYGRDSFVRLLLEFKAEVDPL 146 Query: 619 NYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLAD 798 + +G T L A V+ L+ NANI + G + +A + + R+ L Sbjct: 147 SDKGTTPLQLAIIRERSSCVKILLDHNANID----IQNGFLLRYAVIKSNHSYCRMFL-- 200 Query: 799 YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLL 978 + +D + + + G TPLH++AL V C ++L Sbjct: 201 -----------------QRGADTNLG----------RLEDGQTPLHLSALRDDVLCARML 233 Query: 979 LDLGASVSEVTIEDGTTI 1032 + GA + E T + Sbjct: 234 YNYGADTNTRNYEGQTPL 251
>Q9H672:ASB7_HUMAN Ankyrin repeat and SOCS box protein 7 - Homo sapiens (Human)| Length = 318 Score = 81.6 bits (200), Expect = 1e-14 Identities = 70/241 (29%), Positives = 106/241 (43%), Gaps = 32/241 (13%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 A A G V +LE G N R+ G T L + G V+ + A+ D + Sbjct: 21 AVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIG 80 Query: 730 GGTAIHFAALHGHARCLRLVL-ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV-N 903 G TA+H+AA+HG AR RL+L ++Y I N + A + D V+++ Sbjct: 81 GFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVA--AHYGRDSFVRLLLE 138 Query: 904 WKA------DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDG-------------- 1023 +KA D G TPL +A + CV++LLD A++ I++G Sbjct: 139 FKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANID---IQNGFLLRYAVIKSNHSY 195 Query: 1024 ----------TTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAH 1173 T + L G TPLH +A + +C ++L GA+ +N G TPL V+ Sbjct: 196 CRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSI 255 Query: 1174 S 1176 S Sbjct: 256 S 256 Score = 50.4 bits (119), Expect = 3e-05 Identities = 44/160 (27%), Positives = 65/160 (40%) Frame = +1 Query: 727 NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNW 906 NG T +HF+A G RC+R+ L +H + V D Sbjct: 46 NGWTLLHFSAARGKERCVRVFL--------------EHGADPTVKDLI------------ 79 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 GG T LH AA++G +L+L+ + + G TPLH AA G Sbjct: 80 ---GGFTALHYAAMHGRARIARLMLESEYRSDIINAKSN-------DGWTPLHVAAHYGR 129 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 +LL+ A + + G+TPL +A R+S +IL Sbjct: 130 DSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKIL 169 Score = 46.6 bits (109), Expect = 4e-04 Identities = 50/198 (25%), Positives = 79/198 (39%), Gaps = 2/198 (1%) Frame = +1 Query: 445 AARDGDLQEARALLE--YNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLR 618 AA G + AR +LE Y + + G +PLH AA G V LLLE E++ Sbjct: 88 AAMHGRARIARLMLESEYRSDIINAKSNDGW-TPLHVAAHYGRDSFVRLLLEFKAEVDPL 146 Query: 619 NYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLAD 798 + +G T L A V+ L+ NANI + G + +A + + R+ L Sbjct: 147 SDKGTTPLQLAIIRERSSCVKILLDHNANID----IQNGFLLRYAVIKSNHSYCRMFL-- 200 Query: 799 YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLL 978 + +D + + + G TPLH++AL V C ++L Sbjct: 201 -----------------QRGADTNLG----------RLEDGQTPLHLSALRDDVLCARML 233 Query: 979 LDLGASVSEVTIEDGTTI 1032 + GA + E T + Sbjct: 234 YNYGADTNTRNYEGQTPL 251
>Q08DV6:ASB3_BOVIN Ankyrin repeat and SOCS box protein 3 - Bos taurus (Bovine)| Length = 525 Score = 81.6 bits (200), Expect = 1e-14 Identities = 56/195 (28%), Positives = 96/195 (49%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH AA+QGH +I+ +LLE+G + N T L A + G +V++ L+ + AN++ + Sbjct: 83 LHLAASQGHWKIIQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLRYGANVNGSH 142 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 + G A+H A+ G+A ++L+L K +++E D Sbjct: 143 SMCGWNALHQASFQGNAEIIKLLL--------------KKGANKECQD------------ 176 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACG 1080 D G+TPL +AA G +E + +L+ GA V+ ++ +TPL AA Sbjct: 177 ----DFGITPLFVAAQYGKLESLSILISSGADVNCQALDK----------ATPLFIAAQE 222 Query: 1081 GNAVCCQLLIARGAN 1125 G+ C +LL++ GA+ Sbjct: 223 GHTECVELLLSSGAD 237 Score = 71.2 bits (173), Expect = 2e-11 Identities = 58/195 (29%), Positives = 94/195 (48%), Gaps = 8/195 (4%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L A +G + R LL Y + + G N+ LH A+ QG+ EI+ LLL+ G Sbjct: 116 LFLAVENGQIDVLRLLLRYGANVNGSHSMCGWNA-LHQASFQGNAEIIKLLLKKGANKEC 174 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ G T L A QYG E + L+ A+++ L+ T + AA GH C+ L+L+ Sbjct: 175 QDDFGITPLFVAAQYGKLESLSILISSGADVN-CQALDKATPLFIAAQEGHTECVELLLS 233 Query: 796 -----DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGG---LTPLHMAALN 951 D + N+ Q ++ ++ D L+ + N D G ++P++ A L Sbjct: 234 SGADPDLYCNEDNW--QLPIHAAAQMGHTKILDL-LIPLTNRVCDTGPNKVSPVYSAVLG 290 Query: 952 GHVECVQLLLDLGAS 996 GH EC+++LL G S Sbjct: 291 GHEECLEMLLQSGYS 305 Score = 63.2 bits (152), Expect = 4e-09 Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 4/260 (1%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE---INL 615 AAR+G+++ R LL+ + G P+H A+ E + +L+ + I Sbjct: 17 AAREGNVKVLRKLLKKGRSIDVADNRGWM--PIHEASYHNSVECLRMLIRADSSENYIKT 74 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 + + G AL A GHW+++Q L+ A+ + T L T + A +G LRL+L Sbjct: 75 KTFEGFCALHLAASQGHWKIIQILLEAGADPNATT-LEETTPLFLAVENGQIDVLRLLLR 133 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 Y ++ +G M W A LH A+ G+ E ++L Sbjct: 134 -YGANV----------------------NGSHSMCGWNA------LHQASFQGNAEIIKL 164 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGST 1155 LL GA+ +D G TPL AA G +LI+ GA++ + +T Sbjct: 165 LLKKGANKE---CQDDF-------GITPLFVAAQYGKLESLSILISSGADVNCQALDKAT 214 Query: 1156 PLMV-AHSWHRNSIEEILSN 1212 PL + A H +E +LS+ Sbjct: 215 PLFIAAQEGHTECVELLLSS 234
>Q8WXH4:ASB11_HUMAN Ankyrin repeat and SOCS box protein 11 - Homo sapiens (Human)| Length = 323 Score = 81.6 bits (200), Expect = 1e-14 Identities = 80/271 (29%), Positives = 108/271 (39%) Frame = +1 Query: 394 LVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHE 573 + G C A L AA G L + L+ + + R S LH A GH Sbjct: 55 IYGGISDCWADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTI--NRVSSLHEACLGGHVA 112 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 LLE+G +N G T L AC G V L+ F A +L + IH A Sbjct: 113 CAKALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEVHL--ASPIHEA 170 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 GH C+ ++LA+ V EV TPL Sbjct: 171 VKRGHRECMEILLANNV------------NIDHEVPQLG------------------TPL 200 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA 1113 ++A V+CV+ LL+LGASV + G +D TPLH AA N LL Sbjct: 201 YVACTYQRVDCVKKLLELGASV-----DHGQWLD------TPLHAAARQSNVEVIHLLTD 249 Query: 1114 RGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 GANL +NA G + L +A ++S+E+ L Sbjct: 250 YGANLKRRNAQGKSALDLAAP--KSSVEQAL 278
>Q5B0V6:AKR1_EMENI Palmitoyltransferase akr1 - Emericella nidulans (Aspergillus| nidulans) Length = 737 Score = 81.6 bits (200), Expect = 1e-14 Identities = 73/260 (28%), Positives = 113/260 (43%), Gaps = 7/260 (2%) Frame = +1 Query: 427 GERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE 606 GE ++ AR G++ + L + A YS G +PLH+AA + + L++SG + Sbjct: 65 GEDIMQVARIGEVSVMQKLFDEKKFTANYSDEEGI-TPLHWAAINNQYAMCKFLIDSGAD 123 Query: 607 INLRNYRG-QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLR 783 +N + T M A Q H+ +V L+ + A+ TD + G +H A + G+A L Sbjct: 124 VNAKGGESVATPAMWAAQRCHYYIVHLLLQYGADPLLTD-VQGYNILHLATIDGNAFLLV 182 Query: 784 LVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVE 963 L+L +P V +V+ + G T L AA G+ Sbjct: 183 LLLHQEIP---------------------------VDVVDQQ---GHTGLMWAAYKGYPA 212 Query: 964 CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNA 1143 CV L L GA+ + V +DG G PLH+A G+ C ++ GA+ A Sbjct: 213 CVDLFLRWGANPNAV--DDG--------GLAPLHWALVKGSLPCVLKILEYGADRFATTT 262 Query: 1144 SGSTPLMVA------HSWHR 1185 G TP +VA H W+R Sbjct: 263 DGKTPALVAQEMNTRHVWYR 282
>Q8Q0U0:Y045_METMA Putative ankyrin repeat protein MM_0045 - Methanosarcina mazei| (Methanosarcina frisia) Length = 360 Score = 81.3 bits (199), Expect = 2e-14 Identities = 76/281 (27%), Positives = 133/281 (47%), Gaps = 8/281 (2%) Frame = +1 Query: 388 LSLVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGH 567 + + N FG + + + A++ G + LL N Y G+ + L AA +G+ Sbjct: 56 MDFISNLFGRDKN-QSFLEASKQGQTENVEKLLRSNKVDVNYQDAYGKTA-LISAADKGY 113 Query: 568 HEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIH 747 +++ LL+ESG ++L++ G TAL+ A + +++ L+ A+++ D NG TA+ Sbjct: 114 RDVIGLLIESGPNLDLQDENGNTALISAAKIERGDIIDLLVKNGADLNFQDE-NGETALK 172 Query: 748 FAALHGHARCLRLVLADYVPSIPNFLN-QTKHRSSEEVSDADFDDDGLVKM-------VN 903 FA G+ +AD + LN Q ++ + + AD + ++ +N Sbjct: 173 FAVKVGYKN-----IADQLIDAGTDLNIQDENGETALICAADRAHRDIAELLIKAGADLN 227 Query: 904 WKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGG 1083 + + G T L A GH V+LL++ GA ++ ++D +G+T L YAA G Sbjct: 228 IQDNSGKTALVAATKIGHKGIVELLVNAGA---DLNLQD-------KNGNTALIYAADRG 277 Query: 1084 NAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 LLI GA+L + +G T LM + R I E+L Sbjct: 278 YRDIVNLLIEGGASLNIPDEAGLTALMFSAQTGRKDIVELL 318 Score = 58.2 bits (139), Expect = 1e-07 Identities = 43/163 (26%), Positives = 79/163 (48%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA + H +I LL+++G ++N+++ G+TAL+ A + GH +V+ L+ A+++ D N Sbjct: 207 AADRAHRDIAELLIKAGADLNIQDNSGKTALVAATKIGHKGIVELLVNAGADLNLQD-KN 265 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 G TA+ +AA G+ + L++ + +S + D Sbjct: 266 GNTALIYAADRGYRDIVNLLI--------------EGGASLNIPD--------------- 296 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 + GLT L +A G + V+LL+ GA ++ + T DL Sbjct: 297 -EAGLTALMFSAQTGRKDIVELLIKAGADINIEDKNNKTAADL 338 Score = 51.6 bits (122), Expect = 1e-05 Identities = 32/86 (37%), Positives = 50/86 (58%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 N+ L YAA +G+ +IV+LL+E G +N+ + G TALM + Q G ++V+ L+ A+I+ Sbjct: 267 NTALIYAADRGYRDIVNLLIEGGASLNIPDEAGLTALMFSAQTGRKDIVELLIKAGADIN 326 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLV 789 D N TA AA G + L+ Sbjct: 327 IED-KNNKTAADLAAEVGFEEIVDLL 351
>Q09YG9:CTTB2_SAIBB Cortactin-binding protein 2 - Saimiri boliviensis boliviensis| (Bolivian squirrel monkey) Length = 1659 Score = 81.3 bits (199), Expect = 2e-14 Identities = 63/196 (32%), Positives = 94/196 (47%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++ +LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 705 GRPTLLQQAAAQGNVTLLLMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEA 764 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH C+ L++A DA+ Sbjct: 765 QVNAADK-NGFTPLCAAAAQGHFECVELLIA---------------------YDAN---- 798 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N ADGG TPL++A NG+ EC++LLL+ G + T + G TP+ Sbjct: 799 -----INHAADGGQTPLYLACKNGNKECIKLLLEAGTDRNVKTTD----------GWTPV 843 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 844 HAAVDTGNVDSLKLLM 859 Score = 69.3 bits (168), Expect = 6e-11 Identities = 65/214 (30%), Positives = 94/214 (43%), Gaps = 6/214 (2%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 710 LQQAAAQGNVTLLLMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLSAEAQVNA 768 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH+E V+ L+ ++ANI H D G T ++ A +G+ C++L+L Sbjct: 769 ADKNGFTPLCAAAAQGHFECVELLIAYDANINHAAD--GGQTPLYLACKNGNKECIKLLL 826 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 E +D N K G TP+H A G+V+ ++ Sbjct: 827 -------------------EAGTDR-----------NVKTTDGWTPVHAAVDTGNVDSLK 856 Query: 973 LLL-----DLGASVSEVTIEDGTTIDLLGSGSTP 1059 LL+ G S SE E G DL G G +P Sbjct: 857 LLMYHRVPAHGNSFSEEESESG-VFDLDGGGESP 889 Score = 45.8 bits (107), Expect = 7e-04 Identities = 44/190 (23%), Positives = 76/190 (40%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L +AA G + L+ Y+ + ++ GG+ +PL+ A G+ E + LLLE+G + N+ Sbjct: 777 LCAAAAQGHFECVELLIAYDANI-NHAADGGQ-TPLYLACKNGNKECIKLLLEAGTDRNV 834 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 + G T + A G+ + ++ LM H + + L G Sbjct: 835 KTTDGWTPVHAAVDTGNVDSLKLLMYHRVPAHGNSFSEEESESGVFDLDGG--------- 885 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 ++ S+ V ADF +N G T H+AA G C+++ Sbjct: 886 ----------GESPEGKSKPVVTADF--------INHANREGWTAAHIAASKGFKNCLEI 927 Query: 976 LLDLGASVSE 1005 L G +E Sbjct: 928 LCRHGGLETE 937
>Q5RFS1:ASB11_PONPY Ankyrin repeat and SOCS box protein 11 - Pongo pygmaeus (Orangutan)| Length = 323 Score = 81.3 bits (199), Expect = 2e-14 Identities = 80/271 (29%), Positives = 108/271 (39%) Frame = +1 Query: 394 LVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHE 573 + G C A L AA G L + L+ + + R S LH A GH Sbjct: 55 IYGGISDCWADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTI--NRVSSLHEACLGGHVA 112 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 LLE+G +N G T L AC G V L+ F A +L + IH A Sbjct: 113 CAKALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQFEVHL--ASPIHEA 170 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 GH C+ ++LA+ V EV TPL Sbjct: 171 VKRGHRECMEILLANNV------------NIDHEVPQLG------------------TPL 200 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA 1113 ++A V+CV+ LL+LGASV + G +D TPLH AA N LL Sbjct: 201 YVACTYQRVDCVKKLLELGASV-----DHGQWLD------TPLHAAARQSNVEVIHLLTD 249 Query: 1114 RGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 GANL +NA G + L +A ++S+E+ L Sbjct: 250 YGANLKRRNAQGKSALDLAAP--KSSVEQAL 278
>Q07E41:CTTB2_DASNO Cortactin-binding protein 2 - Dasypus novemcinctus (Nine-banded| armadillo) Length = 1665 Score = 79.7 bits (195), Expect = 4e-14 Identities = 62/196 (31%), Positives = 92/196 (46%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 711 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAKA 770 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 I D NG T + AA GH C+ L++A + Sbjct: 771 QIDAAD-KNGFTPLCAAAAQGHFECVELLIAYHA-------------------------- 803 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 ++ ADGG TPL++A NG+ EC+++LL+ G S T + G TP+ Sbjct: 804 ----NIDHAADGGQTPLYLACKNGNKECIKVLLEAGTDRSVKTRD----------GWTPV 849 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 850 HAAVDTGNVDSLKLLM 865 Score = 65.1 bits (157), Expect = 1e-09 Identities = 53/198 (26%), Positives = 88/198 (44%), Gaps = 7/198 (3%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 740 NYSCEDGHSALYSAAKNGHTDCVRLLLNAKAQIDAADKNGF--TPLCAAAAQGHFECVEL 797 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHG 765 L+ I+ GQT L AC+ G+ E ++ L+ + +G T +H A G Sbjct: 798 LIAYHANIDHAADGGQTPLYLACKNGNKECIKVLLEAGTD-RSVKTRDGWTPVHAAVDTG 856 Query: 766 HARCLRLVLADYVPSIPNFLNQTKHRSSE-EVSDADFDDDGLVK------MVNWKADGGL 924 + L+L++ P++ + LN+ + ++ +G K ++N G Sbjct: 857 NVDSLKLLMYHRAPTLGHSLNEEEPEPGAFDLDQGQEGSEGTAKPVVPTDLINHANREGW 916 Query: 925 TPLHMAALNGHVECVQLL 978 T H+AA G C+++L Sbjct: 917 TAAHIAASKGFKNCLEIL 934 Score = 64.7 bits (156), Expect = 1e-09 Identities = 69/256 (26%), Positives = 102/256 (39%), Gaps = 28/256 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + +I+ Sbjct: 716 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLNAKAQIDA 774 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH+E V+ L+ ++ANI H D G T ++ A +G+ C++++L Sbjct: 775 ADKNGFTPLCAAAAQGHFECVELLIAYHANIDHAAD--GGQTPLYLACKNGNKECIKVLL 832 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G TP+H A G+V+ ++ Sbjct: 833 ----------------------------EAGTDRSV--KTRDGWTPVHAAVDTGNVDSLK 862 Query: 973 LL-----------------------LDLGASVSEVTIEDGTTIDLLG----SGSTPLHYA 1071 LL LD G SE T + DL+ G T H A Sbjct: 863 LLMYHRAPTLGHSLNEEEPEPGAFDLDQGQEGSEGTAKPVVPTDLINHANREGWTAAHIA 922 Query: 1072 ACGGNAVCCQLLIARG 1119 A G C ++L G Sbjct: 923 ASKGFKNCLEILCRHG 938 Score = 56.6 bits (135), Expect = 4e-07 Identities = 38/119 (31%), Positives = 58/119 (48%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL+ A Sbjct: 713 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLNAKA 770 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 + +G TPL AA G+ C +LLIA AN+ G TPL +A Sbjct: 771 QIDAAD----------KNGFTPLCAAAAQGHFECVELLIAYHANIDHAADGGQTPLYLA 819
>Q5U312:RAI14_RAT Ankycorbin - Rattus norvegicus (Rat)| Length = 978 Score = 79.3 bits (194), Expect = 6e-14 Identities = 68/259 (26%), Positives = 114/259 (44%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 +RL+ A +GD ++ +LL A G+ + H AAA+GH E + +++ GV++ Sbjct: 21 DRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTA-FHLAAAKGHVECLKVMVTHGVDV 79 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 ++ G +AL A + GH E ++ L+ + + D L G TA+H+AA G + ++++ Sbjct: 80 TAQDSSGHSALHIAAKNGHPEYIKKLLQYKSPAESVDNL-GKTALHYAAAQGSLQAVQVL 138 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 +H+S + D D G PL +A NGH E Sbjct: 139 --------------CEHKSPINLKDLD----------------GNIPLLVAIQNGHSEAC 168 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 LLD GA V+ +G T L A G+A + LI +GA+L ++ G Sbjct: 169 HFLLDHGADVNSRD----------KNGRTALMLACETGSANTVEALIKKGADLNLVDSLG 218 Query: 1150 STPLMVAHSWHRNSIEEIL 1206 L + I+ +L Sbjct: 219 HNALYYSKLSENAGIQSLL 237 Score = 62.0 bits (149), Expect = 1e-08 Identities = 45/150 (30%), Positives = 72/150 (48%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G LQ + L E+ + G N PL A GH E LL+ G ++N R+ Sbjct: 126 AAAQGSLQAVQVLCEHKSPINLKDLDG--NIPLLVAIQNGHSEACHFLLDHGADVNSRDK 183 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G+TALM AC+ G V+ L+ A+++ D L G A++++ L +A L+L+ + Sbjct: 184 NGRTALMLACETGSANTVEALIKKGADLNLVDSL-GHNALYYSKLSENAGIQSLLLSK-I 241 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + TK + ++VS + G K Sbjct: 242 SQDADLKTPTKAKQHDQVSKISSERSGTPK 271 Score = 55.8 bits (133), Expect = 7e-07 Identities = 40/125 (32%), Positives = 60/125 (48%) Frame = +1 Query: 418 SASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLES 597 S+ L AA++G + + LL+Y G + LHYAAAQG + V +L E Sbjct: 84 SSGHSALHIAAKNGHPEYIKKLLQYKSPAESVDNLG--KTALHYAAAQGSLQAVQVLCEH 141 Query: 598 GVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARC 777 INL++ G L+ A Q GH E L+ A+++ D NG TA+ A G A Sbjct: 142 KSPINLKDLDGNIPLLVAIQNGHSEACHFLLDHGADVNSRD-KNGRTALMLACETGSANT 200 Query: 778 LRLVL 792 + ++ Sbjct: 201 VEALI 205
>Q8UVC1:INVS_DANRE Inversin - Danio rerio (Zebrafish) (Brachydanio rerio)| Length = 1021 Score = 79.3 bits (194), Expect = 6e-14 Identities = 74/264 (28%), Positives = 116/264 (43%), Gaps = 32/264 (12%) Frame = +1 Query: 475 RALLEYNPR--LARYSTFGGRNSPLHYAAAQGHHEIVSLLLE-SGVEINLRNYRGQTALM 645 R +LE P L + + GR +PLH+A A G+ +V +L G + + +T L Sbjct: 195 RCILEAAPTESLLNWQDYEGR-TPLHFAVADGNEAVVEVLTSYEGCSVTAYDNLFRTPLH 253 Query: 646 QACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADY-VPSIPNF 822 A GH ++V L+ N + G T +H+ A A + + L + V P+ Sbjct: 254 WAALLGHAKIVHLLLERNKSGMIPSDSQGATPLHYGAQSNFADTVAVFLKHHSVRDEPDL 313 Query: 823 LNQTKH-----RSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDL 987 +T + S +V D + +N G T LH AAL+GHV V+LLL+ Sbjct: 314 EGRTAFMWAAGKGSNDVIKIMLDLKKDID-INMTDKYGGTALHAAALSGHVSTVRLLLEQ 372 Query: 988 GASVSEVT----------------------IEDGTTIDLLG-SGSTPLHYAACGGNAVCC 1098 G V + I+ G +DL+ G + LH+AA GGNA C Sbjct: 373 GGMVDPLDVMKHTPLFRACEMGHRDVILTLIKGGARVDLVDIDGHSALHWAALGGNAEVC 432 Query: 1099 QLLIARGANLAAKNASGSTPLMVA 1170 ++L+ G + ++ +G TPL A Sbjct: 433 EVLMENGISPNLQDQAGRTPLQCA 456 Score = 76.3 bits (186), Expect = 5e-13 Identities = 61/207 (29%), Positives = 101/207 (48%), Gaps = 6/207 (2%) Frame = +1 Query: 520 FGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 +GG + LH AA GH V LLLE G ++ + T L +AC+ GH +V+ TL+ Sbjct: 349 YGG--TALHAAALSGHVSTVRLLLEQGGMVDPLDVMKHTPLFRACEMGHRDVILTLIKGG 406 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 A + D ++G +A+H+AAL G+A +++ + + PN +Q + + A + Sbjct: 407 ARVDLVD-IDGHSALHWAALGGNAEVCEVLMENGIS--PNLQDQAGRTPLQCAAYAGY-I 462 Query: 880 DGLVKMVNWKAD------GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 + + ++ AD G T LH + NG+++ V+LLL GA + + + Sbjct: 463 NCMALLIQHDADPNIQDKEGRTALHWSCNNGYLDAVKLLLGCGAFPNHMEHTE------- 515 Query: 1042 GSGSTPLHYAACGGNAVCCQLLIARGA 1122 TPL YA G + Q L+ GA Sbjct: 516 -ERYTPLDYALLGEHQELTQFLLEHGA 541 Score = 65.5 bits (158), Expect = 9e-10 Identities = 64/216 (29%), Positives = 100/216 (46%), Gaps = 7/216 (3%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLF--NANI 708 +PLHY A + V++ L+ + + G+TA M A G +V++ ++ + +I Sbjct: 284 TPLHYGAQSNFADTVAVFLKHHSVRDEPDLEGRTAFMWAAGKGSNDVIKIMLDLKKDIDI 343 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + TD GGTA+H AAL GH +RL+L P L+ KH + D L Sbjct: 344 NMTDKY-GGTALHAAALSGHVSTVRLLLEQGGMVDP--LDVMKHTPLFRACEMGHRDVIL 400 Query: 889 VKM-----VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS 1053 + V+ G + LH AAL G+ E ++L++ G S + ++D +G Sbjct: 401 TLIKGGARVDLVDIDGHSALHWAALGGNAEVCEVLMENGISPN---LQDQ-------AGR 450 Query: 1054 TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL 1161 TPL AA G C LLI A+ ++ G T L Sbjct: 451 TPLQCAAYAGYINCMALLIQHDADPNIQDKEGRTAL 486 Score = 60.1 bits (144), Expect = 4e-08 Identities = 68/275 (24%), Positives = 115/275 (41%), Gaps = 12/275 (4%) Frame = +1 Query: 442 SAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 +AA +GD L+ + FG +PL Y + +LL++G IN + Sbjct: 14 AAAVNGDKNTLHKLITESALRDSEDQFG--RTPLMYCVLADRLDCAEVLLKAGAGINKTD 71 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADY 801 + +TAL A Q G+ ++ L+ +A+ D L T +H A+ H ++ L L+L Sbjct: 72 HSQRTALHLAAQKGNVRFMKLLLSRHADWRLKD-LEEMTPLHLASRHSSSKPLSLLLKHM 130 Query: 802 VPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM-------VNWKADGGLTPLHMAALNGH- 957 P + Q +++ + A ++ VK+ + G PLH AA N H Sbjct: 131 APGEVD--TQDRNKQTALHWSAFYNHPEHVKLLIKHDSNIGIPDSEGKIPLHWAAHNKHP 188 Query: 958 --VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA-RGANL 1128 V+ +L+ + S + +D G TPLH+A GN ++L + G ++ Sbjct: 189 NATRTVRCILEAAPTESLLNWQD-------YEGRTPLHFAVADGNEAVVEVLTSYEGCSV 241 Query: 1129 AAKNASGSTPL-MVAHSWHRNSIEEILSNEPGGQI 1230 A + TPL A H + +L G I Sbjct: 242 TAYDNLFRTPLHWAALLGHAKIVHLLLERNKSGMI 276
>Q9CQ31:ASB11_MOUSE Ankyrin repeat and SOCS box protein 11 - Mus musculus (Mouse)| Length = 323 Score = 79.3 bits (194), Expect = 6e-14 Identities = 75/259 (28%), Positives = 100/259 (38%) Frame = +1 Query: 394 LVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHE 573 + G C A L AA G L + L+ + + R S LH A GH Sbjct: 55 IYGGLSDCWADRSPLHEAAAQGRLLALKTLIAQGINVNLVTI--NRVSSLHEACLGGHVA 112 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 LLE+G +N + G T L AC G V L+ F A YL + IH A Sbjct: 113 CAKALLENGAHVNAQTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEIYL--ASPIHEA 170 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 GH C+ ++L V +EV TPL Sbjct: 171 VKRGHRECMEILLTKDV------------NIEQEVPQLG------------------TPL 200 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA 1113 ++A V+CV+ LL+LGASV + G +D TPLH A + LL Sbjct: 201 YVACTYQRVDCVKKLLELGASV-----DHGQWLD------TPLHAAVRQSSVEVINLLTV 249 Query: 1114 RGANLAAKNASGSTPLMVA 1170 GANL +NA G + L +A Sbjct: 250 YGANLNLRNAQGKSALDLA 268 Score = 51.6 bits (122), Expect = 1e-05 Identities = 33/106 (31%), Positives = 48/106 (45%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 VN ++ LH A L GHV C + LL+ GA V+ T+ G+TPL A C Sbjct: 91 VNLVTINRVSSLHEACLGGHVACAKALLENGAHVNAQTVH----------GATPLFNACC 140 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNE 1215 G+A C +L+ GA + S HR +E +L+ + Sbjct: 141 SGSAACVNVLLEFGAKAQLEIYLASPIHEAVKRGHRECMEILLTKD 186
>Q3SZE4:ASB11_BOVIN Ankyrin repeat and SOCS box protein 11 - Bos taurus (Bovine)| Length = 323 Score = 79.3 bits (194), Expect = 6e-14 Identities = 78/271 (28%), Positives = 109/271 (40%) Frame = +1 Query: 394 LVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHE 573 + G C A L AA G L + L+ + + R S LH A GH Sbjct: 55 IFGEISDCWADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTI--NRVSSLHEACLGGHVA 112 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 LLE+G +N G T L AC G V L+ F A +L + IH A Sbjct: 113 CAKALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEVHL--ASPIHEA 170 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 G+ C+ ++LA+ V N + H TPL Sbjct: 171 VKRGNRECMEILLANNV----NIDQEVPHLG--------------------------TPL 200 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA 1113 + A ++CV+ LL+LGA+V+ G +D TPLH AA + LLI Sbjct: 201 YAACTYQRLDCVKKLLELGANVNH-----GQWLD------TPLHAAAKQNSVEIIHLLID 249 Query: 1114 RGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 GANL KNA G + L +A ++S+E+ L Sbjct: 250 YGANLKCKNAQGQSALDLAAP--KSSVEQAL 278
>Q9Z148:EHMT2_MOUSE Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 - Mus| musculus (Mouse) Length = 1263 Score = 78.6 bits (192), Expect = 1e-13 Identities = 68/252 (26%), Positives = 116/252 (46%), Gaps = 2/252 (0%) Frame = +1 Query: 433 RLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEIN 612 +L + + G+LQ+ +L N S + +PLH AA +G EI +LL++G IN Sbjct: 706 QLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 765 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 + + +T LM+A H EV + ++ ++ + +G T +H AA G+ + L+L Sbjct: 766 AVDKQQRTPLMEAVVNNHLEVARYMVQLGGCVYSKEE-DGSTCLHHAAKIGNLEMVSLLL 824 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 S+ +V VN + GG TP+ AA + H++ ++ Sbjct: 825 -----------------STGQVD------------VNAQDSGGWTPIIWAAEHKHIDVIR 855 Query: 973 LLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGS 1152 +LL GA V+ E+ LH+A+ G+A ++L+ +L A N G Sbjct: 856 MLLTRGADVTLTDNEENIC----------LHWASFTGSAAIAEVLLNAQCDLHAVNYHGD 905 Query: 1153 TPLMVA--HSWH 1182 TPL +A S+H Sbjct: 906 TPLHIAARESYH 917 Score = 58.9 bits (141), Expect = 8e-08 Identities = 56/202 (27%), Positives = 95/202 (47%), Gaps = 1/202 (0%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESG-VEIN 612 L+ A + L+ AR +++ + YS ++ LH+AA G+ E+VSLLL +G V++N Sbjct: 775 LMEAVVNNHLEVARYMVQLGGCV--YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 832 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 ++ G T ++ A ++ H +V++ L+ A++ TD +H+A+ G A ++L Sbjct: 833 AQDSGGWTPIIWAAEHKHIDVIRMLLTRGADVTLTDN-EENICLHWASFTGSAAIAEVLL 891 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 +A D + VN+ D TPLH+AA + +CV Sbjct: 892 -----------------------NAQCD----LHAVNYHGD---TPLHIAARESYHDCVL 921 Query: 973 LLLDLGASVSEVTIEDGTTIDL 1038 L L GA+ E T DL Sbjct: 922 LFLSRGANPELRNKEGDTAWDL 943 Score = 40.0 bits (92), Expect = 0.039 Identities = 68/279 (24%), Positives = 106/279 (37%), Gaps = 2/279 (0%) Frame = +1 Query: 382 GFLSLVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQ 561 G LS VG G G + A E R L ++PR L+ + Q Sbjct: 669 GCLSAVGLPPG---PGREALEKALVIQESERRKKLRFHPR------------QLYLSVKQ 713 Query: 562 GHHEIVSLLLESGVEINLRNYRG--QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGG 735 G + V L+L ++ N ++ + +T L A Q G E+ L+ ANI+ D Sbjct: 714 GELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQR- 772 Query: 736 TAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKAD 915 T + A ++ H R ++ L V K + Sbjct: 773 TPLMEAVVNNHLEVARYMVQ------------------------------LGGCVYSKEE 802 Query: 916 GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVC 1095 G T LH AA G++E V LLL G +V +D G TP+ +AA + Sbjct: 803 DGSTCLHHAAKIGNLEMVSLLLSTGQV--DVNAQDS-------GGWTPIIWAAEHKHIDV 853 Query: 1096 CQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSN 1212 ++L+ RGA++ + + L A +I E+L N Sbjct: 854 IRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 892
>Q96KQ7:EHMT2_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 - Homo| sapiens (Human) Length = 1210 Score = 78.6 bits (192), Expect = 1e-13 Identities = 69/252 (27%), Positives = 116/252 (46%), Gaps = 2/252 (0%) Frame = +1 Query: 433 RLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEIN 612 +L + + G+LQ+ +L N S + +PLH AA +G EI +LL++G IN Sbjct: 653 QLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 712 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 + + +T LM+A H EV + ++ ++ + +G T +H AA G+ + L+L Sbjct: 713 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEE-DGSTCLHHAAKIGNLEMVSLLL 771 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 S+ +V VN + GG TP+ AA + H+E ++ Sbjct: 772 -----------------STGQVD------------VNAQDSGGWTPIIWAAEHKHIEVIR 802 Query: 973 LLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGS 1152 +LL GA V+ E+ LH+A+ G+A ++L+ +L A N G Sbjct: 803 MLLTRGADVTLTDNEENIC----------LHWASFTGSAAIAEVLLNARCDLHAVNYHGD 852 Query: 1153 TPLMVA--HSWH 1182 TPL +A S+H Sbjct: 853 TPLHIAARESYH 864 Score = 58.9 bits (141), Expect = 8e-08 Identities = 57/202 (28%), Positives = 95/202 (47%), Gaps = 1/202 (0%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESG-VEIN 612 L+ A + L+ AR +++ + YS ++ LH+AA G+ E+VSLLL +G V++N Sbjct: 722 LMEAVVNNHLEVARYMVQRGGCV--YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVN 779 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 ++ G T ++ A ++ H EV++ L+ A++ TD +H+A+ G A ++L Sbjct: 780 AQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDN-EENICLHWASFTGSAAIAEVLL 838 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 +A D + VN+ D TPLH+AA + +CV Sbjct: 839 -----------------------NARCD----LHAVNYHGD---TPLHIAARESYHDCVL 868 Query: 973 LLLDLGASVSEVTIEDGTTIDL 1038 L L GA+ E T DL Sbjct: 869 LFLSRGANPELRNKEGDTAWDL 890 Score = 40.4 bits (93), Expect = 0.030 Identities = 68/279 (24%), Positives = 106/279 (37%), Gaps = 2/279 (0%) Frame = +1 Query: 382 GFLSLVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQ 561 G LS VG G G + A E R L ++PR L+ + Q Sbjct: 616 GCLSAVGLPLG---PGREALEKALVIQESERRKKLRFHPR------------QLYLSVKQ 660 Query: 562 GHHEIVSLLLESGVEINLRNYRG--QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGG 735 G + V L+L ++ N ++ + +T L A Q G E+ L+ ANI+ D Sbjct: 661 GELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQR- 719 Query: 736 TAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKAD 915 T + A ++ H R ++ G V K + Sbjct: 720 TPLMEAVVNNHLEVARYMV---------------------------QRGGCVYS---KEE 749 Query: 916 GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVC 1095 G T LH AA G++E V LLL G +V +D G TP+ +AA + Sbjct: 750 DGSTCLHHAAKIGNLEMVSLLLSTGQV--DVNAQDS-------GGWTPIIWAAEHKHIEV 800 Query: 1096 CQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSN 1212 ++L+ RGA++ + + L A +I E+L N Sbjct: 801 IRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 839
>Q9EP71:RAI14_MOUSE Ankycorbin - Mus musculus (Mouse)| Length = 979 Score = 78.2 bits (191), Expect = 1e-13 Identities = 67/259 (25%), Positives = 114/259 (44%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 +RL+ A +GD ++ +LL A G+ + H AAA+GH E + +++ GV++ Sbjct: 21 DRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTA-FHLAAAKGHVECLKVMVTHGVDV 79 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 ++ G +AL A + GH E ++ L+ + + D +G TA+H+AA G + ++L+ Sbjct: 80 TAQDSSGHSALHVAAKNGHPECIRKLLQYKSPAENIDN-SGKTALHYAAAQGCLQAVQLL 138 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 +H+S + D D G PL +A NGH E Sbjct: 139 --------------CEHKSPINLKDLD----------------GNIPLLVAVQNGHSEAC 168 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 LLD GA V+ +G T L A G++ LI +GA+L+ ++ G Sbjct: 169 HFLLDHGADVNSRD----------KNGRTALMLACETGSSNTVDALIKKGADLSLVDSLG 218 Query: 1150 STPLMVAHSWHRNSIEEIL 1206 L + I+ +L Sbjct: 219 HNALHYSKLSENAGIQNLL 237 Score = 62.0 bits (149), Expect = 1e-08 Identities = 46/150 (30%), Positives = 70/150 (46%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G LQ + L E+ + G N PL A GH E LL+ G ++N R+ Sbjct: 126 AAAQGCLQAVQLLCEHKSPINLKDLDG--NIPLLVAVQNGHSEACHFLLDHGADVNSRDK 183 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G+TALM AC+ G V L+ A++ D L G A+H++ L +A L+L+ + Sbjct: 184 NGRTALMLACETGSSNTVDALIKKGADLSLVDSL-GHNALHYSKLSENAGIQNLLLSK-I 241 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + TK + ++VS + G K Sbjct: 242 SQDADLKTPTKPKQHDQVSKISSERSGTPK 271
>Q07E15:CTTB2_MUSPF Cortactin-binding protein 2 - Mustela putorius furo (European| domestic ferret) (Mustela furo) Length = 1645 Score = 77.8 bits (190), Expect = 2e-13 Identities = 63/196 (32%), Positives = 93/196 (47%), Gaps = 1/196 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 706 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 765 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH +C+ L++A Y +I Sbjct: 766 QVNAAD-KNGFTPLCAAAAQGHFKCVELLIA-YNANI----------------------- 800 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 N AD G TPL++A NG+ EC++ LL+ G S T + G TP+ Sbjct: 801 ------NHAADEGQTPLYLACKNGNKECIKHLLEAGTDRSVKTRD----------GWTPV 844 Query: 1063 HYAACGGNAVCCQLLI 1110 H A GN +LL+ Sbjct: 845 HAAVDAGNVDSLKLLM 860 Score = 60.8 bits (146), Expect = 2e-08 Identities = 80/332 (24%), Positives = 129/332 (38%), Gaps = 37/332 (11%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 711 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLNAEAQVNA 769 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH++ V+ L+ +NANI H D G T ++ A +G+ C++ +L Sbjct: 770 ADKNGFTPLCAAAAQGHFKCVELLIAYNANINHAAD--EGQTPLYLACKNGNKECIKHLL 827 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G TP+H A G+V+ ++ Sbjct: 828 ----------------------------EAGTDRSV--KTRDGWTPVHAAVDAGNVDSLK 857 Query: 973 LL-----------------------LDLGASVSEVTIEDGTTIDLLG----SGSTPLHYA 1071 LL LD G E T + DL+ G T H A Sbjct: 858 LLMYHRAPARRNSLHEEEPESGVFDLDQGEESPEGTSKPVIPADLINHADREGWTAAHIA 917 Query: 1072 ACGGNAVCCQLLIA-RGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSP 1248 A G C ++L RG ++ T VA ++ +E + + + +I SP Sbjct: 918 ASKGFKDCLEILCKHRGLEPERRDKCNRTAHDVATDDCKHLLENLNALKIPVRISGGESP 977 Query: 1249 --------YLCLPLMSIMSIARECGWRYLNKS 1320 + C + ++I ++ W +K+ Sbjct: 978 PGNYGSDDFECENTICALNIRKQTSWEDFSKA 1009
>Q8VHK2:CSKI1_RAT Caskin-1 - Rattus norvegicus (Rat)| Length = 1430 Score = 77.8 bits (190), Expect = 2e-13 Identities = 70/277 (25%), Positives = 117/277 (42%), Gaps = 27/277 (9%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRN------------SPLHYAAAQGHHE 573 + LV A + D+ A+ LL+ PR + G S LH+AA G+ E Sbjct: 5 QELVQAVKAEDVGTAQRLLQ-RPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTE 63 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 ++SLLLE+ +++++ +G L A G E ++ L+L + G +H A Sbjct: 64 LISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMK-LVLKAGSAVNVPSDEGHIPLHLA 122 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV----------- 900 A HGH ++L S P ++ + + +F G+V+++ Sbjct: 123 AQHGHYDVSEMLLQH--QSNPCIVDNSGKTPLDLA--CEFGRVGVVQLLLSSNMCAALLE 178 Query: 901 ----NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 + G +PLH+AA NGH++ ++LLL G ++ T T LH Sbjct: 179 PRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQT-----------KSGTALHE 227 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW 1179 AA G +LL+ G N +N T L + H + Sbjct: 228 AALCGKTEVVRLLLDSGINAQVRNTYSQTALDIVHQF 264
>Q6P9K8:CSKI1_MOUSE Caskin-1 - Mus musculus (Mouse)| Length = 1431 Score = 77.8 bits (190), Expect = 2e-13 Identities = 70/277 (25%), Positives = 117/277 (42%), Gaps = 27/277 (9%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRN------------SPLHYAAAQGHHE 573 + LV A + D+ A+ LL+ PR + G S LH+AA G+ E Sbjct: 5 QELVQAVKAEDVGTAQRLLQ-RPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTE 63 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 ++SLLLE+ +++++ +G L A G E ++ L+L + G +H A Sbjct: 64 LISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMK-LVLKAGSAVNVPSDEGHIPLHLA 122 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV----------- 900 A HGH ++L S P ++ + + +F G+V+++ Sbjct: 123 AQHGHYDVSEMLLQH--QSNPCMVDNSGKTPLDLA--CEFGRVGVVQLLLSSNMCAALLE 178 Query: 901 ----NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 + G +PLH+AA NGH++ ++LLL G ++ T T LH Sbjct: 179 PRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQT-----------KSGTALHE 227 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW 1179 AA G +LL+ G N +N T L + H + Sbjct: 228 AALCGKTEVVRLLLDSGINAQVRNTYSQTALDIVHQF 264
>Q3V096:ANR42_MOUSE Ankyrin repeat domain-containing protein 42 - Mus musculus (Mouse)| Length = 527 Score = 77.8 bits (190), Expect = 2e-13 Identities = 68/258 (26%), Positives = 111/258 (43%), Gaps = 4/258 (1%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A R GD+++ ++E L + +PLH+AA G E + LL SG + Sbjct: 33 AVRAGDVKQLSDIVERGANLNEVDALH-QFTPLHWAAHSGSLECLHWLLWSGADATQTTT 91 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 RG TA A G +Q L++ AN+ D G T +H AA HGH+ L+++L V Sbjct: 92 RGWTAAHIAAIRGQDACLQALIINGANLATQDD-RGCTPLHLAATHGHSFSLQIMLRSGV 150 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 D + WK P+H A+ +G + C+QLL+ Sbjct: 151 ------------------------DPSVTDKREWK------PVHYASFHGRLGCLQLLVK 180 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGAN----LAAKNASGS 1152 G + +V +G+ P+H AA G+ C + L++R + L A N +G Sbjct: 181 WGCGIEDVDY----------NGNLPVHLAAMEGHLHCLKFLLSRMNSATQALKAFNDNGE 230 Query: 1153 TPLMVAHSWHRNSIEEIL 1206 L +A + + ++ E + Sbjct: 231 NVLDLAQRFLKQNVVEFI 248 Score = 77.4 bits (189), Expect = 2e-13 Identities = 65/223 (29%), Positives = 100/223 (44%), Gaps = 11/223 (4%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA GH + ++L SGV+ ++ + R + A +G +Q L+ + I Sbjct: 128 TPLHLAATHGHSFSLQIMLRSGVDPSVTDKREWKPVHYASFHGRLGCLQLLVKWGCGIED 187 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDAD--FDDDGL 888 DY NG +H AA+ GH CL+ +L+ + + + + E V D F + Sbjct: 188 VDY-NGNLPVHLAAMEGHLHCLKFLLSRMNSATQAL--KAFNDNGENVLDLAQRFLKQNV 244 Query: 889 VKMVNWKADGG---------LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 V+ + G P H+AA G +E ++ L+ G V + D Sbjct: 245 VEFIQGAQYEGSHPDDHDDLAFPGHVAAFKGDLEVLKKLI--GDGVINLNERDD------ 296 Query: 1042 GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 +GSTP+H AA G+ C Q LI GA N +G TP VA Sbjct: 297 -NGSTPMHKAAGQGHIDCLQWLIEMGAESNITNKAGETPSDVA 338 Score = 40.4 bits (93), Expect = 0.030 Identities = 19/52 (36%), Positives = 30/52 (57%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTL 687 ++P+H AA QGH + + L+E G E N+ N G+T A ++ H V+ L Sbjct: 299 STPMHKAAGQGHIDCLQWLIEMGAESNITNKAGETPSDVAKRFAHLAAVKLL 350
>Q8NFD2:ANKK1_HUMAN Ankyrin repeat and protein kinase domain-containing protein 1 - Homo| sapiens (Human) Length = 765 Score = 77.8 bits (190), Expect = 2e-13 Identities = 73/263 (27%), Positives = 108/263 (41%), Gaps = 38/263 (14%) Frame = +1 Query: 496 PRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEV 675 PR + + +PLH+ AQG E V LLL V+++ + G T L+ A Q ++ Sbjct: 351 PRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDL 410 Query: 676 VQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLAD---------------YVPS 810 L+ A+ +R D +G +HFAA +G RL+L ++ + Sbjct: 411 CALLLAHGADANRVDE-DGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAA 469 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 NF N + S + N G TPLH+AA GHV V+LL G Sbjct: 470 QNNFENVARLLVSRQADP------------NLHEAEGKTPLHVAAYFGHVSLVKLLTSQG 517 Query: 991 ASVS----------------------EVTIEDGTTIDLLG-SGSTPLHYAACGGNAVCCQ 1101 A + + ++ G D L SG PLH AA G + C+ Sbjct: 518 AELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICK 577 Query: 1102 LLIARGANLAAKNASGSTPLMVA 1170 +L+ GA+L G TPL +A Sbjct: 578 MLLRYGASLELPTHQGWTPLHLA 600 Score = 67.0 bits (162), Expect = 3e-10 Identities = 62/226 (27%), Positives = 89/226 (39%) Frame = +1 Query: 538 PLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT 717 PLH AAA+G + I +LL G + L ++G T L A GH E++ L +AN+ Sbjct: 563 PLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGAL 622 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM 897 +N T +H AA HG + +L + PN Q+ Sbjct: 623 GAVNW-TPLHLAARHGEEAVVSALLQ--CGADPNAAEQS--------------------- 658 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 G TPLH+A V LL+ A+V G TP H AA Sbjct: 659 -------GWTPLHLAVQRSTFLSVINLLEHHANVHARN----------KVGWTPAHLAAL 701 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNE 1215 GN ++L+ GA L ++ TPL +A + I L + Sbjct: 702 KGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGK 747 Score = 52.8 bits (125), Expect = 6e-06 Identities = 57/186 (30%), Positives = 78/186 (41%), Gaps = 10/186 (5%) Frame = +1 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 Y N T +HF G +RL+LA V + QT + + A L ++ Sbjct: 359 YENKVTPLHFLVAQGSVEQVRLLLAHEV----DVDCQTASGYTPLLIAAQDQQPDLCALL 414 Query: 901 -------NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTP 1059 N + G PLH AA NG +LLLD GA V E G TP Sbjct: 415 LAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQERE----------GWTP 464 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSN---EPGGQI 1230 LH AA +LL++R A+ A G TPL VA + S+ ++L++ E Q Sbjct: 465 LHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQ 524 Query: 1231 RTLPSP 1248 R L +P Sbjct: 525 RNLRTP 530 Score = 50.8 bits (120), Expect = 2e-05 Identities = 50/198 (25%), Positives = 85/198 (42%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L +AA G + LL Y L + G +PLH AA +GH EI+ LL ES + Sbjct: 564 LHTAAARGKYLICKMLLRYGASLELPTHQGW--TPLHLAAYKGHLEIIHLLAESHANMGA 621 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 T L A ++G VV L+ A+ + + +G T +H A Sbjct: 622 LGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQ-SGWTPLHLAVQRS---------- 670 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 + + +N +H ++ V+ + G TP H+AAL G+ +++ Sbjct: 671 ----TFLSVINLLEHHAN----------------VHARNKVGWTPAHLAALKGNTAILKV 710 Query: 976 LLDLGASVSEVTIEDGTT 1029 L++ GA ++ ++DG + Sbjct: 711 LVEAGA---QLDVQDGVS 725
>Q66H07:FANK1_RAT Fibronectin type 3 and ankyrin repeat domains 1 protein - Rattus| norvegicus (Rat) Length = 344 Score = 77.4 bits (189), Expect = 2e-13 Identities = 64/223 (28%), Positives = 101/223 (45%), Gaps = 1/223 (0%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 L AA +G+ +V +L+ +G ++NL+N G+ +LM AC GH +VV+ L A+ D Sbjct: 148 LMVAAQKGYTRLVKILISNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRKHGASWDARD 207 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 L G TA+H+AA GH + ++ D + D D G Sbjct: 208 -LGGCTALHWAADGGHCPVIDWMIKD-------------------GCEVDVVDTG----- 242 Query: 901 NWKADGGLTPL-HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 G TPL ++A+ G + LL++ GA +V + D G TPL A Sbjct: 243 -----SGWTPLMRVSAVTGSQKVASLLIEAGA---DVNVRD-------KDGKTPLMVAVL 287 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 + QLL+ +GA+ KN G L +A + R ++ +L Sbjct: 288 NNHEQLVQLLLDKGADATVKNEFGKGVLEMARVFDRQNVLSLL 330 Score = 40.8 bits (94), Expect = 0.023 Identities = 20/58 (34%), Positives = 34/58 (58%) Frame = +1 Query: 517 TFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLM 690 T G + +A G ++ SLL+E+G ++N+R+ G+T LM A H ++VQ L+ Sbjct: 241 TGSGWTPLMRVSAVTGSQKVASLLIEAGADVNVRDKDGKTPLMVAVLNNHEQLVQLLL 298
>Q9DAM9:FANK1_MOUSE Fibronectin type 3 and ankyrin repeat domains 1 protein - Mus| musculus (Mouse) Length = 344 Score = 77.4 bits (189), Expect = 2e-13 Identities = 64/226 (28%), Positives = 103/226 (45%), Gaps = 1/226 (0%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 L AA +G+ +V +L+ +G ++NL+N G+ +LM AC GH +VV+ L A+ D Sbjct: 148 LMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWEARD 207 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 L G TA+H+AA GH + ++ D + D D G Sbjct: 208 -LGGCTALHWAADGGHCSVIDWMIKD-------------------GCEVDVVDTG----- 242 Query: 901 NWKADGGLTPL-HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 G TPL ++A+ G + LL++ GA V+ + +DG TPL A Sbjct: 243 -----SGWTPLMRVSAVTGSQKVASLLIEAGADVN-IKDKDG---------KTPLMVAVL 287 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNE 1215 + QLL+ +GA+ KN G L +A + R ++ +L + Sbjct: 288 NNHEQLVQLLLDKGADATVKNEFGKGVLEMARVFDRQNVLSLLEEK 333 Score = 63.2 bits (152), Expect = 4e-09 Identities = 67/233 (28%), Positives = 105/233 (45%), Gaps = 5/233 (2%) Frame = +1 Query: 487 EYNPRLARYSTFGGRNSP-LHYAAAQGHHEIVSLLLESG-VEINLRNYRGQTALMQACQY 660 EY+P ++ +T +S H A + +++ +LE G V I++ N G TALM A Q Sbjct: 95 EYSPVVSVATTREPISSEHFHRAVSVNDEDLLLRILEGGHVMIDVPNKFGFTALMVAAQK 154 Query: 661 GHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKH 840 G+ +V+ L+ +++ + +G ++ A GH ++ + +H Sbjct: 155 GYTRLVKILVSNGTDVNLKNG-SGKDSLMLACYAGHLDVVKYL--------------RRH 199 Query: 841 RSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIED 1020 +S E D GG T LH AA GH SV + I+D Sbjct: 200 GASWEARDL----------------GGCTALHWAADGGH-----------CSVIDWMIKD 232 Query: 1021 GTTIDLL--GSGSTPL-HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G +D++ GSG TPL +A G+ LLI GA++ K+ G TPLMVA Sbjct: 233 GCEVDVVDTGSGWTPLMRVSAVTGSQKVASLLIEAGADVNIKDKDGKTPLMVA 285 Score = 49.3 bits (116), Expect = 6e-05 Identities = 56/203 (27%), Positives = 82/203 (40%), Gaps = 1/203 (0%) Frame = +1 Query: 397 VGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEI 576 V N FG +A L+ AA+ G + + L+ N G++S L A GH ++ Sbjct: 139 VPNKFGFTA----LMVAAQKGYTRLVKILVS-NGTDVNLKNGSGKDS-LMLACYAGHLDV 192 Query: 577 VSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAI-HFA 753 V L G R+ G TAL A GH V+ ++ + D +G T + + Sbjct: 193 VKYLRRHGASWEARDLGGCTALHWAADGGHCSVIDWMIKDGCEVDVVDTGSGWTPLMRVS 252 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 A+ G + L++ + AD VN K G TPL Sbjct: 253 AVTGSQKVASLLIE---------------------AGAD---------VNIKDKDGKTPL 282 Query: 934 HMAALNGHVECVQLLLDLGASVS 1002 +A LN H + VQLLLD GA + Sbjct: 283 MVAVLNNHEQLVQLLLDKGADAT 305
>Q8IYU2:HACE1_HUMAN E3 ubiquitin-protein ligase HACE1 - Homo sapiens (Human)| Length = 909 Score = 77.0 bits (188), Expect = 3e-13 Identities = 67/212 (31%), Positives = 96/212 (45%), Gaps = 1/212 (0%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + S LH AA G E + LLL+ G N ++ G T L A + G + + L+ ++A++ Sbjct: 65 KRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADV 124 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + + G TAIH+ A++G L H + VSD D +D Sbjct: 125 NICNN-EGLTAIHWLAVNGRTELL-------------------HDLVQHVSDVDVEDAM- 163 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 G T LH+A NGH VQ LLD GA ++ + SG+TPL++ Sbjct: 164 ----------GQTALHVACQNGHKTTVQCLLDSGADINRPNV----------SGATPLYF 203 Query: 1069 AACGGNAVCCQLLIARGAN-LAAKNASGSTPL 1161 A G Q+L+ RGA L KN G TPL Sbjct: 204 ACSHGQRDTAQILLLRGAKYLPDKN--GVTPL 233 Score = 59.3 bits (142), Expect = 6e-08 Identities = 42/124 (33%), Positives = 69/124 (55%), Gaps = 3/124 (2%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AAR+G + LLEY+ + + G + +H+ A G E++ L++ ++++ + Sbjct: 105 AARNGQKKCMSKLLEYSADVNICNNEG--LTAIHWLAVNGRTELLHDLVQHVSDVDVEDA 162 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGH---ARCLRLVLA 795 GQTAL ACQ GH VQ L+ A+I+R + ++G T ++FA HG A+ L L A Sbjct: 163 MGQTALHVACQNGHKTTVQCLLDSGADINRPN-VSGATPLYFACSHGQRDTAQILLLRGA 221 Query: 796 DYVP 807 Y+P Sbjct: 222 KYLP 225 Score = 55.5 bits (132), Expect = 9e-07 Identities = 52/192 (27%), Positives = 80/192 (41%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA G + +S LLE ++N+ N G TA+ G E++ L+ +++ Sbjct: 100 TPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDV 159 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 D + G TA+H A +GH ++ +L S AD Sbjct: 160 EDAM-GQTALHVACQNGHKTTVQCLLD---------------------SGAD-------- 189 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 +N G TPL+ A +G + Q+LL GA + D +G TPL Sbjct: 190 -INRPNVSGATPLYFACSHGQRDTAQILLLRGAKY----LPD-------KNGVTPLDLCV 237 Query: 1075 CGGNAVCCQLLI 1110 GG C++LI Sbjct: 238 QGGYGETCEVLI 249 Score = 54.3 bits (129), Expect = 2e-06 Identities = 39/125 (31%), Positives = 53/125 (42%), Gaps = 23/125 (18%) Frame = +1 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL------------- 1041 N++ G TPLH+AA NG +C+ LL+ A V+ E T I L Sbjct: 92 NYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLV 151 Query: 1042 ----------GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS 1191 G T LH A G+ Q L+ GA++ N SG+TPL A S + Sbjct: 152 QHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRD 211 Query: 1192 IEEIL 1206 +IL Sbjct: 212 TAQIL 216 Score = 46.2 bits (108), Expect = 6e-04 Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 3/94 (3%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A GH V LL+SG +IN N G T L AC +G + Q L+L A Sbjct: 168 LHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAK----- 222 Query: 721 YL---NGGTAIHFAALHGHARCLRLVLADYVPSI 813 YL NG T + G+ VL Y P + Sbjct: 223 YLPDKNGVTPLDLCVQGGYGETCE-VLIQYHPRL 255 Score = 32.7 bits (73), Expect = 6.3 Identities = 17/37 (45%), Positives = 23/37 (62%) Frame = +1 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 LH AA G+ C LL+ +GAN ++ SG TPL +A Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLA 105
>Q8WXD9:CSKI1_HUMAN Caskin-1 - Homo sapiens (Human)| Length = 1431 Score = 77.0 bits (188), Expect = 3e-13 Identities = 68/277 (24%), Positives = 118/277 (42%), Gaps = 27/277 (9%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRN------------SPLHYAAAQGHHE 573 + LV A + D+ A+ LL+ PR + G S LH+AA G+ E Sbjct: 5 QELVQAVKAEDVGTAQRLLQ-RPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTE 63 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 ++SLLLE+ +++++ +G L A G E ++ ++ + ++ G +H A Sbjct: 64 LISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSD-EGHIPLHLA 122 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV----------- 900 A HGH ++L S P ++ + + +F G+V+++ Sbjct: 123 AQHGHYDVSEMLLQH--QSNPCMVDNSGKTPLDLA--CEFGRVGVVQLLLSSNMCAALLE 178 Query: 901 ----NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 + G +PLH+AA NGH++ ++LLL G ++ T T LH Sbjct: 179 PRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQT-----------KSGTALHE 227 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW 1179 AA G +LL+ G N +N T L + H + Sbjct: 228 AALCGKTEVVRLLLDSGINAHVRNTYSQTALDIVHQF 264 Score = 48.5 bits (114), Expect = 1e-04 Identities = 49/189 (25%), Positives = 82/189 (43%) Frame = +1 Query: 640 LMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPN 819 L+Q + G +++ + N N D G +A+H AAL+G+ + L+L Sbjct: 22 LLQRPRPGKAKLLGSTKKINVNFQDPD---GFSALHHAALNGNTELISLLL--------- 69 Query: 820 FLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASV 999 E A V+ K + G+ PLH AA G E ++L+L G++V Sbjct: 70 -----------EAQAA----------VDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAV 108 Query: 1000 SEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW 1179 + + E G PLH AA G+ ++L+ +N + SG TPL +A + Sbjct: 109 NIPSDE----------GHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEF 158 Query: 1180 HRNSIEEIL 1206 R + ++L Sbjct: 159 GRVGVVQLL 167
>Q9WV72:ASB3_MOUSE Ankyrin repeat and SOCS box protein 3 - Mus musculus (Mouse)| Length = 525 Score = 77.0 bits (188), Expect = 3e-13 Identities = 54/195 (27%), Positives = 93/195 (47%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A +QGH +I +LLE+G + N T L A + G +V++ L+ AN++ + Sbjct: 83 LHLAVSQGHWKITQILLEAGADPNETTLEETTPLFLAVESGRIDVLKLLLQHGANVNGSH 142 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 ++G ++H A+ G+A ++L+L K + E D Sbjct: 143 SMSGWNSLHQASFQGNAETIKLLL--------------KQGADRECQD------------ 176 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACG 1080 D G+TPL +AA G +E + +L+ GA+V+ ++ +TPL AA Sbjct: 177 ----DFGITPLFVAAQYGKLESMSILISSGANVNCQALDK----------ATPLFIAAQE 222 Query: 1081 GNAVCCQLLIARGAN 1125 G+ C +LL++ GA+ Sbjct: 223 GHTKCVELLLSSGAD 237 Score = 60.8 bits (146), Expect = 2e-08 Identities = 69/260 (26%), Positives = 108/260 (41%), Gaps = 4/260 (1%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE---INL 615 AAR+G+++ R LL+ + G P+H AA E + +L+ + I Sbjct: 17 AAREGNVKILRKLLKKGRSVDVADNRGWM--PIHEAAYHNAVECLQMLIHTDSSENYIKA 74 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 + + G AL A GHW++ Q L+ A+ + T L T + A G L+L+L Sbjct: 75 KTFEGFCALHLAVSQGHWKITQILLEAGADPNETT-LEETTPLFLAVESGRIDVLKLLL- 132 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 +H ++ +G M W + LH A+ G+ E ++L Sbjct: 133 -------------QHGANV---------NGSHSMSGWNS------LHQASFQGNAETIKL 164 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGST 1155 LL GA D D G TPL AA G +LI+ GAN+ + +T Sbjct: 165 LLKQGA--------DRECQD--DFGITPLFVAAQYGKLESMSILISSGANVNCQALDKAT 214 Query: 1156 PLMV-AHSWHRNSIEEILSN 1212 PL + A H +E +LS+ Sbjct: 215 PLFIAAQEGHTKCVELLLSS 234 Score = 35.8 bits (81), Expect = 0.74 Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 3/139 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINL--RNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 +PL AA +GH + V LLL SG + +L Q + A Q GH E + L++ N Sbjct: 214 TPLFIAAQEGHTKCVELLLSSGADPDLYCNEDNWQLPIHAAAQMGHTETLD-LLIPRTNR 272 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLAD-YVPSIPNFLNQTKHRSSEEVSDADFDDDG 885 + + ++ A G CL ++L + Y P L D D G Sbjct: 273 ACDTEPDKVSPVYSAVFGGREECLEMLLQNGYSPDAQMCLVFGFSSPLCMAFQKDCDFSG 332 Query: 886 LVKMVNWKADGGLTPLHMA 942 +V ++ K L LH+A Sbjct: 333 IVNIL-LKYGAQLNELHLA 350
>Q9J4Z6:V244_FOWPV Putative ankyrin repeat protein FPV244 - Fowlpox virus (FPV)| Length = 668 Score = 76.3 bits (186), Expect = 5e-13 Identities = 70/263 (26%), Positives = 122/263 (46%), Gaps = 3/263 (1%) Frame = +1 Query: 391 SLVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAA-AQGH 567 +++ N + + L+ A R+ DL+ + LL Y+ + S +N+PLHYA A Sbjct: 229 AIIDNRSNINKNDLSLLKAIRNTDLETS--LLLYDSGFSVNSIDVYKNTPLHYAVQAPSL 286 Query: 568 HEIVSLLLESGVEINLRNYRGQTALMQACQYGH-WEVVQTLMLFNANIHRTDYLNGGTAI 744 +V LLE G+++N +N +G+T L + G+ E ++TL++ A+++ D ++ Sbjct: 287 SRLVPKLLERGIDVNAKNIKGETPLYLMAKNGYDTENIRTLIMRGADVNAAD------SL 340 Query: 745 HFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGL 924 + LH + L Y ++ L + ++ + D Sbjct: 341 YITPLHQAS-----TLDRYKDTVITLLELGANVNARDYCDK------------------- 376 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA-VCCQ 1101 TP+H AA+ +V + LLD GA + ++ + GT LH+A G N + + Sbjct: 377 TPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTV----------LHFALYGTNPYMSVK 426 Query: 1102 LLIARGANLAAKNASGSTPLMVA 1170 LI RGAN+ +KN STPL A Sbjct: 427 TLIDRGANVNSKNKYLSTPLHYA 449 Score = 53.9 bits (128), Expect = 3e-06 Identities = 67/242 (27%), Positives = 107/242 (44%), Gaps = 30/242 (12%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +P+HYAA +G+ ++V+LLL G ++N+ + L A + + ++ ++ +NI++ Sbjct: 180 TPIHYAAERGNTKMVNLLLSYGADVNIITLDDLSVLEYAVDSKNIDTIKAIIDNRSNINK 239 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLAD---YVPSIPNFLNQTKHRSSEEVSDADFDDDG 885 D L+ AI L L+L D V SI + N H + + S + Sbjct: 240 ND-LSLLKAIRNTDLE-----TSLLLYDSGFSVNSIDVYKNTPLHYAVQAPSLSRLVPKL 293 Query: 886 LVK--MVNWKADGGLTPLHMAALNGH-VECVQLLLDLGASV--------------SEVTI 1014 L + VN K G TPL++ A NG+ E ++ L+ GA V S + Sbjct: 294 LERGIDVNAKNIKGETPLYLMAKNGYDTENIRTLIMRGADVNAADSLYITPLHQASTLDR 353 Query: 1015 EDGTTIDLLGSGS----------TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 T I LL G+ TP+HYAA N V L+ GA++ A + T L Sbjct: 354 YKDTVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTVLH 413 Query: 1165 VA 1170 A Sbjct: 414 FA 415
>Q9XZC0:LCTA_LATMA Alpha-latrocrustotoxin - Latrodectus mactans (Black widow spider)| Length = 1395 Score = 76.3 bits (186), Expect = 5e-13 Identities = 62/235 (26%), Positives = 114/235 (48%), Gaps = 8/235 (3%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH + +L+ E+ IN+++ G T L A + + L+ N + Sbjct: 581 TPLHLSITSNSRAARTLINETPAGINIKSNSGLTPLHLAVLQNNLSAAKVLVKSNKKVKL 640 Query: 715 TDYLNGG-TAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDA--DFD-DD 882 + N G T +H+A++ G+ ++ ++ + N + K+ + ++ FD Sbjct: 641 NEMDNNGMTPLHYASMLGNLEFVKYFTSEQGIDV-NAKTKVKNWTPLHLAILFKKFDVAQ 699 Query: 883 GLVKM----VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSG 1050 L+++ ++ +AD +TPLH+AA G+ + V+ +L+ GA V + T +G Sbjct: 700 SLLQVRNIDISTRADQAITPLHLAAATGNSQIVKTILNSGAVVDQET----------ANG 749 Query: 1051 STPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNE 1215 T LH A N Q LIA+GAN+ AK GSTPL A + + +I ++L ++ Sbjct: 750 FTALHLAIMNPNTETPQFLIAKGANINAKTNDGSTPLHFAAALGKTNIFQLLMDK 804 Score = 58.9 bits (141), Expect = 8e-08 Identities = 61/211 (28%), Positives = 90/211 (42%), Gaps = 9/211 (4%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH- 711 +PLH AAA G+ +IV +L SG ++ G TAL A + E Q L+ ANI+ Sbjct: 718 TPLHLAAATGNSQIVKTILNSGAVVDQETANGFTALHLAIMNPNTETPQFLIAKGANINA 777 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSI--PNFLNQTKHRSS------EEVSDA 867 +T+ +G T +HFAA G +L L D +I N +NQ + V Sbjct: 778 KTN--DGSTPLHFAAALGKTNIFQL-LMDKGANIKAENLINQMPIHEAVVNGHLAIVKML 834 Query: 868 DFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS 1047 D L+ N + + P ++AA + + L GA V+E Sbjct: 835 IEQDSSLMNAKNMRDE---YPFYLAAEKRYKDVFNYLESKGADVNEKN----------ND 881 Query: 1048 GSTPLHYAACGGNAVCCQLLIARGANLAAKN 1140 G+T LH + G Q LI GA+ +N Sbjct: 882 GNTLLHLFSINGEVEVVQFLIQNGADFRLRN 912 Score = 50.1 bits (118), Expect = 4e-05 Identities = 42/154 (27%), Positives = 66/154 (42%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 ++PLH+AAA G I LL++ G I N Q + +A GH +V+ L+ ++++ Sbjct: 783 STPLHFAAALGKTNIFQLLMDKGANIKAENLINQMPIHEAVVNGHLAIVKMLIEQDSSLM 842 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 + + AA + + N+L E AD Sbjct: 843 NAKNMRDEYPFYLAAEKRY------------KDVFNYL---------ESKGAD------- 874 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 VN K + G T LH+ ++NG VE VQ L+ GA Sbjct: 875 --VNEKNNDGNTLLHLFSINGEVEVVQFLIQNGA 906 Score = 43.1 bits (100), Expect = 0.005 Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +1 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 ++N G TPLH+A+ + + V+ LL+ GA V+ T + T PLH AA Sbjct: 503 LLNVPDKNGYTPLHIASERKNNDFVKFLLEKGADVNVRTFANELT---------PLHLAA 553 Query: 1075 CGGNAVCCQLLIA-RGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGG 1224 + + L+ RG ++ AK +G TPL ++ + + + +++ P G Sbjct: 554 RQDFTIIVKTLMEKRGIDVNAKERAGFTPLHLSITSNSRAARTLINETPAG 604 Score = 37.4 bits (85), Expect = 0.26 Identities = 21/52 (40%), Positives = 28/52 (53%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS 1053 VN + TPLH AA N H++ V+ L+ GA V+ E+ IDL G S Sbjct: 1119 VNTRNKEQFTPLHAAASNDHIDVVKYLIQKGADVNAKGDENLKPIDLAGEKS 1170 Score = 33.9 bits (76), Expect = 2.8 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 9/222 (4%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 N+ LH + G E+V L+++G + LRN ++ A ++GH +V + N Sbjct: 883 NTLLHLFSINGEVEVVQFLIQNGADFRLRNKERKSFFDLAVEFGHAGIVGYAIEENKVDL 942 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDAD----FDD 879 + Y G I + A+ + R+ + Y N + + + + D F Sbjct: 943 QEPY--RGKTILYHAICDSVKYDRIEVVRYFVETLNEDQCSPLQEAAAYAHLDLVKYFVQ 1000 Query: 880 DGLVKMVNWKADGGLTPLHMAALNGHVECVQLL-----LDLGASVSEVTIEDGTTIDLLG 1044 + + + D ++PL +A + V+ LD+ + + T + D Sbjct: 1001 ERGINPTAFNNDNQVSPLCIAIVGAPCGFVKSCDTPERLDVVEYLVDKTPDINKECDT-- 1058 Query: 1045 SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 STP+ A G LI GA+ K G PL +A Sbjct: 1059 QQSTPVSSAVYGNKVSILNYLIRNGAD-PNKKVRGDPPLFIA 1099
>Q2QLG9:CTTB2_OTOGA Cortactin-binding protein 2 - Otolemur garnettii (Small-eared galago)| (Garnett's greater bushbaby) Length = 1655 Score = 76.3 bits (186), Expect = 5e-13 Identities = 65/207 (31%), Positives = 98/207 (47%), Gaps = 6/207 (2%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN G +AL A + GH + V+ L+ A Sbjct: 700 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 759 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 ++ D NG T + AA GH C+ L++A DA Sbjct: 760 QVNAAD-KNGFTPLCAAAAQGHFECVELLIA---------------------YDAH---- 793 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N AD G TPL++A NG+ EC++LLL+ G + + T + G TP+ Sbjct: 794 -----INHAADEGQTPLYLACKNGNKECIKLLLEAGTNRNVKTRD----------GWTPV 838 Query: 1063 HYAACGGNAVCCQLLI-----ARGANL 1128 H G+ +LL+ ARG +L Sbjct: 839 HAVVDTGDVDSLKLLMYHRAPARGNSL 865 Score = 72.8 bits (177), Expect = 5e-12 Identities = 56/198 (28%), Positives = 91/198 (45%), Gaps = 7/198 (3%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 729 NYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGF--TPLCAAAAQGHFECVEL 786 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHG 765 L+ IN GQT L AC+ G+ E ++ L+ N +G T +H G Sbjct: 787 LIAYDAHINHAADEGQTPLYLACKNGNKECIKLLLEAGTN-RNVKTRDGWTPVHAVVDTG 845 Query: 766 HARCLRLVLADYVPSIPNFLNQTKHRSS-EEVSDADFDDDGLVK------MVNWKADGGL 924 L+L++ P+ N LN+ + +S ++ + + +G+ K ++N+ G Sbjct: 846 DVDSLKLLMYHRAPARGNSLNEEEPKSDIFDLDEGEESPEGISKPVIPADLINYANREGW 905 Query: 925 TPLHMAALNGHVECVQLL 978 T H+AA G C+++L Sbjct: 906 TAAHIAASKGFKNCLEIL 923 Score = 55.8 bits (133), Expect = 7e-07 Identities = 38/119 (31%), Positives = 59/119 (49%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P L Q + + + +++GL +N+ + G + L+ AA NGH +CV+LLL+ A Sbjct: 702 PTLLQQAAAQGNVTLLSMLLNEEGLD--INYSCEDGHSALYSAAKNGHTDCVRLLLNAEA 759 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 V+ +G TPL AA G+ C +LLIA A++ G TPL +A Sbjct: 760 QVNAAD----------KNGFTPLCAAAAQGHFECVELLIAYDAHINHAADEGQTPLYLA 808
>Q8WXK1:ASB15_HUMAN Ankyrin repeat and SOCS box protein 15 - Homo sapiens (Human)| Length = 588 Score = 76.3 bits (186), Expect = 5e-13 Identities = 67/233 (28%), Positives = 115/233 (49%), Gaps = 3/233 (1%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L+ A + G L+++N L + R S +H AA QG +IV+LLL+ G ++L Sbjct: 148 LLIAVKKGSYDMVSTLIKHNTSLDQPCV--KRWSAMHEAAKQGRKDIVALLLKHGGNVHL 205 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 R+ G T L A +YGH +V++ L+ ++ +G + + AA G+ C+ L+L Sbjct: 206 RDGFGVTPLGVAAEYGHCDVLEHLIHKGGDVLALAD-DGASVLFEAAGGGNPDCISLLL- 263 Query: 796 DYVPS--IPNFLNQTK-HRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVEC 966 +Y S +PN HR++ E V N GLTP+H AA + +C Sbjct: 264 EYGGSGNVPNRAGHLPIHRAAYEGHYLALKYLIPVTSKNAIRKSGLTPIHSAADGQNAQC 323 Query: 967 VQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGAN 1125 ++LL++ G V+ + + D + T L++A + C ++L+A GA+ Sbjct: 324 LELLIENGFDVNTL-LADHISQSCDDERKTALYFAVSNNDVHCTEVLLAAGAD 375 Score = 64.7 bits (156), Expect = 1e-09 Identities = 58/209 (27%), Positives = 91/209 (43%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PL A G E V LLE GV N +N +G+T L+ A + G +++V TL+ N ++ + Sbjct: 113 TPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLIAVKKGSYDMVSTLIKHNTSLDQ 172 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + +A+H AA G + L+L KH + + D Sbjct: 173 -PCVKRWSAMHEAAKQGRKDIVALLL--------------KHGGNVHLRDG--------- 208 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 G+TPL +AA GH + ++ L+ G G + L G++ L AA Sbjct: 209 -------FGVTPLGVAAEYGHCDVLEHLIHKG----------GDVLALADDGASVLFEAA 251 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL 1161 GGN C LL+ G + N +G P+ Sbjct: 252 GGGNPDCISLLLEYGGSGNVPNRAGHLPI 280 Score = 35.8 bits (81), Expect = 0.74 Identities = 27/84 (32%), Positives = 39/84 (46%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 G PLH A V+ +Q +L++ S T+ + T D G TPL A G Sbjct: 76 GWFPLHEAV----VQPIQQILEIVLDASYKTLWEFKTCD----GETPLTLAVKAGLVENV 127 Query: 1099 QLLIARGANLAAKNASGSTPLMVA 1170 + L+ +G KN G TPL++A Sbjct: 128 RTLLEKGVWPNTKNDKGETPLLIA 151
>Q3U0D9:HACE1_MOUSE E3 ubiquitin-protein ligase HACE1 - Mus musculus (Mouse)| Length = 909 Score = 75.9 bits (185), Expect = 6e-13 Identities = 66/212 (31%), Positives = 96/212 (45%), Gaps = 1/212 (0%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + S LH AA G E + LLL+ G N ++ G T L A + G + + L+ ++A++ Sbjct: 65 KRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADV 124 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + + G TAIH+ A++G L H + V+D D +D Sbjct: 125 NICNN-EGLTAIHWLAVNGRTELL-------------------HDLVQHVTDVDVEDAM- 163 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 G T LH+A NGH VQ LLD GA ++ + SG+TPL++ Sbjct: 164 ----------GQTALHVACQNGHKTTVQCLLDSGADINRPNV----------SGATPLYF 203 Query: 1069 AACGGNAVCCQLLIARGAN-LAAKNASGSTPL 1161 A G Q+L+ RGA L KN G TPL Sbjct: 204 ACSHGQRDTAQILLLRGAKYLPDKN--GVTPL 233 Score = 60.1 bits (144), Expect = 4e-08 Identities = 42/124 (33%), Positives = 69/124 (55%), Gaps = 3/124 (2%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AAR+G + LLEY+ + + G + +H+ A G E++ L++ ++++ + Sbjct: 105 AARNGQKKCMSKLLEYSADVNICNNEG--LTAIHWLAVNGRTELLHDLVQHVTDVDVEDA 162 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGH---ARCLRLVLA 795 GQTAL ACQ GH VQ L+ A+I+R + ++G T ++FA HG A+ L L A Sbjct: 163 MGQTALHVACQNGHKTTVQCLLDSGADINRPN-VSGATPLYFACSHGQRDTAQILLLRGA 221 Query: 796 DYVP 807 Y+P Sbjct: 222 KYLP 225 Score = 55.1 bits (131), Expect = 1e-06 Identities = 52/192 (27%), Positives = 79/192 (41%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA G + +S LLE ++N+ N G TA+ G E++ L+ ++ Sbjct: 100 TPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTDVDV 159 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 D + G TA+H A +GH ++ +L S AD Sbjct: 160 EDAM-GQTALHVACQNGHKTTVQCLLD---------------------SGAD-------- 189 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 +N G TPL+ A +G + Q+LL GA + D +G TPL Sbjct: 190 -INRPNVSGATPLYFACSHGQRDTAQILLLRGAKY----LPD-------KNGVTPLDLCV 237 Query: 1075 CGGNAVCCQLLI 1110 GG C++LI Sbjct: 238 QGGYGQTCEVLI 249 Score = 54.3 bits (129), Expect = 2e-06 Identities = 39/125 (31%), Positives = 53/125 (42%), Gaps = 23/125 (18%) Frame = +1 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL------------- 1041 N++ G TPLH+AA NG +C+ LL+ A V+ E T I L Sbjct: 92 NYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLV 151 Query: 1042 ----------GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS 1191 G T LH A G+ Q L+ GA++ N SG+TPL A S + Sbjct: 152 QHVTDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRD 211 Query: 1192 IEEIL 1206 +IL Sbjct: 212 TAQIL 216 Score = 46.6 bits (109), Expect = 4e-04 Identities = 33/94 (35%), Positives = 42/94 (44%), Gaps = 3/94 (3%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A GH V LL+SG +IN N G T L AC +G + Q L+L A Sbjct: 168 LHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAK----- 222 Query: 721 YL---NGGTAIHFAALHGHARCLRLVLADYVPSI 813 YL NG T + G+ + VL Y P + Sbjct: 223 YLPDKNGVTPLDLCVQGGYGQTCE-VLIQYHPRL 255 Score = 32.7 bits (73), Expect = 6.3 Identities = 17/37 (45%), Positives = 23/37 (62%) Frame = +1 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 LH AA G+ C LL+ +GAN ++ SG TPL +A Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLA 105
>Q9Z2X3:PSD10_RAT 26S proteasome non-ATPase regulatory subunit 10 - Rattus norvegicus| (Rat) Length = 231 Score = 75.5 bits (184), Expect = 8e-13 Identities = 69/253 (27%), Positives = 114/253 (45%) Frame = +1 Query: 412 GCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 GC S + + A +G L E + + + LA + R + LH+A + GH EIV LL Sbjct: 3 GC-VSNLMVCNLAYNGKLDELKESILADKSLATRTDQDSRTA-LHWACSAGHTEIVEFLL 60 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 + GV +N ++ G + L A G E+V+ L++ A ++ + NG TA+H+AA Sbjct: 61 QLGVPVNEKDDAGWSPLHIAASAGRDEIVKALLIKGAQVNAVNQ-NGCTALHYAA----- 114 Query: 772 RCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALN 951 ++ +H + + + + D K T +H AA Sbjct: 115 ------------------SKNRHEIAVMLLEGGANPDA-------KNHYDATAMHRAAAK 149 Query: 952 GHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLA 1131 G+++ V +LL AS + I+D G+TPLH A +LL+ +GA++ Sbjct: 150 GNLKMVHILLFYKASTN---IQD-------TEGNTPLHLACDEERVEEAKLLVTQGASIY 199 Query: 1132 AKNASGSTPLMVA 1170 +N TPL VA Sbjct: 200 IENKEEKTPLQVA 212 Score = 51.2 bits (121), Expect = 2e-05 Identities = 34/94 (36%), Positives = 46/94 (48%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 T LH A GH E V+ LL LG V+E +G +PLH AA G + Sbjct: 42 TALHWACSAGHTEIVEFLLQLGVPVNEKD----------DAGWSPLHIAASAGRDEIVKA 91 Query: 1105 LIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 L+ +GA + A N +G T L A S +R+ I +L Sbjct: 92 LLIKGAQVNAVNQNGCTALHYAASKNRHEIAVML 125
>Q5ZIJ9:MIB2_CHICK E3 ubiquitin-protein ligase MIB2 - Gallus gallus (Chicken)| Length = 954 Score = 75.5 bits (184), Expect = 8e-13 Identities = 68/269 (25%), Positives = 122/269 (45%), Gaps = 7/269 (2%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A+ G L + LL+ + + G ++ LHYAA ++ +L+ G +L N Sbjct: 472 ASYQGHLDVVKILLQAHATVNLRDEEG--DTALHYAAFGNQADVARVLMAKGAGADLLNN 529 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 TAL A G EVVQ L N +++ D +G T +H+A + + ++ V Sbjct: 530 AKCTALYVAVSQGFTEVVQALCELNCDVNLPD-SHGDTPLHYAITADYKVIIEILTE--V 586 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVK-------MVNWKADGGLTPLHMAALNGHVE 963 P+I + + + S + + K +V+ K + G T LH+AALN H E Sbjct: 587 PNIDFTVQNCQGFNLLHYSALKGNKLAIKKILARARQLVDSKKEDGFTALHLAALNNHKE 646 Query: 964 CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNA 1143 ++L+ G +V +++ TPLH A G+ QLL++ G+++ A++ Sbjct: 647 VAEILIKEGR--CDVNVKN-------NRNQTPLHLAIIQGHVGLVQLLVSEGSDVNAEDE 697 Query: 1144 SGSTPLMVAHSWHRNSIEEILSNEPGGQI 1230 G T + +A R + +L + G++ Sbjct: 698 DGDTAMHIA--LERQQLMSVLMEKREGEM 724
>Q80SY4:MIB1_MOUSE E3 ubiquitin-protein ligase MIB1 - Mus musculus (Mouse)| Length = 1006 Score = 75.5 bits (184), Expect = 8e-13 Identities = 74/264 (28%), Positives = 112/264 (42%), Gaps = 7/264 (2%) Frame = +1 Query: 412 GCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 G A + +A+++G + + LL+ N + G R +H+AA ++ +L Sbjct: 460 GQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDR--AVHHAAFGDEGAVIEVLH 517 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 ++N RN R QT L A GH +VV+TL+ F + D G T +H A Sbjct: 518 RGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQD-SEGDTPLHDAISKKRD 576 Query: 772 RCLRLVL---ADYVPSIPNFLNQTKH---RSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 L ++L AD + N N H R + +V+ K D G T L Sbjct: 577 DILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTAL 636 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLG-SGSTPLHYAACGGNAVCCQLLI 1110 H+AALN HVE +LL+ G +D+ + T LH A + +LL+ Sbjct: 637 HLAALNNHVEVAELLVHQG----------NANLDIQNVNQQTALHLAVERQHTQIVRLLV 686 Query: 1111 ARGANLAAKNASGSTPLMVAHSWH 1182 GA L ++ G TPL A H Sbjct: 687 RAGAKLDIQDKDGDTPLHEALRHH 710 Score = 64.3 bits (155), Expect = 2e-09 Identities = 89/399 (22%), Positives = 139/399 (34%), Gaps = 104/399 (26%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 R +PLH A +GH ++V LL+ G +L++ G T L A +++ L+ A++ Sbjct: 530 RQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADV 589 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 T+ NG A+H AAL G+ +R++L+ +P Sbjct: 590 TITNN-NGFNALHHAALRGNPSAMRVLLS----KLPR----------------------- 621 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG-----------------------ASV 999 +V+ K D G T LH+AALN HVE +LL+ G + Sbjct: 622 PWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQI 681 Query: 1000 SEVTIEDGTTIDLLGS-GSTPLHYAAC--------------------------------- 1077 + + G +D+ G TPLH A Sbjct: 682 VRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQDMQDVGKVDAAWEPSKNTLIMG 741 Query: 1078 ---------GGNAVCCQLLIARGANLAAKNASGSTPLMVAHS---------WHRNSIE-- 1197 ++ C L A GA+L+ +N G +PL + H+ + Sbjct: 742 LGTQGAEKKSAASIAC-FLAANGADLSIRNKKGQSPLDLCPDPSLCKALAKCHKEKVSGQ 800 Query: 1198 ------EILSNE--------------------PGGQIRTLPSPYLCLPLMSIMSIARECG 1299 ++SN+ P G I T LC P + I +E Sbjct: 801 VGSRSPSMISNDSETLEECMVCSDMKRDTLFGPCGHIATCS---LCSPRVKKCLICKE-- 855 Query: 1300 WRYLNKSPVCIDPCAVCLDGSCSVAAEGCKHE-FCTRCA 1413 +S I+ C VC D +V + C H C CA Sbjct: 856 ---QVQSRTKIEECVVCSDKKAAVLFQPCGHMCACENCA 891 Score = 39.3 bits (90), Expect = 0.067 Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 23/119 (19%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIE------------DGTTIDLLGSGS--- 1053 G T + A+ NGHV+ ++LLL V + +G I++L GS Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADL 523 Query: 1054 --------TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 TPLH A G+ + L+ G + + +++ G TPL A S R+ I +L Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
>Q86YT6:MIB1_HUMAN E3 ubiquitin-protein ligase MIB1 - Homo sapiens (Human)| Length = 1006 Score = 75.5 bits (184), Expect = 8e-13 Identities = 74/264 (28%), Positives = 112/264 (42%), Gaps = 7/264 (2%) Frame = +1 Query: 412 GCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 G A + +A+++G + + LL+ N + G R +H+AA ++ +L Sbjct: 460 GQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDR--AVHHAAFGDEGAVIEVLH 517 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 ++N RN R QT L A GH +VV+TL+ F + D G T +H A Sbjct: 518 RGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQD-SEGDTPLHDAISKKRD 576 Query: 772 RCLRLVL---ADYVPSIPNFLNQTKH---RSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 L ++L AD + N N H R + +V+ K D G T L Sbjct: 577 DILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTAL 636 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLG-SGSTPLHYAACGGNAVCCQLLI 1110 H+AALN HVE +LL+ G +D+ + T LH A + +LL+ Sbjct: 637 HLAALNNHVEVAELLVHQG----------NANLDIQNVNQQTALHLAVERQHTQIVRLLV 686 Query: 1111 ARGANLAAKNASGSTPLMVAHSWH 1182 GA L ++ G TPL A H Sbjct: 687 RAGAKLDIQDKDGDTPLHEALRHH 710 Score = 39.3 bits (90), Expect = 0.067 Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 23/119 (19%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIE------------DGTTIDLLGSGS--- 1053 G T + A+ NGHV+ ++LLL V + +G I++L GS Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADL 523 Query: 1054 --------TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 TPLH A G+ + L+ G + + +++ G TPL A S R+ I +L Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
>Q804S5:MIB1_DANRE E3 ubiquitin-protein ligase mib1 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 1030 Score = 74.7 bits (182), Expect = 1e-12 Identities = 73/263 (27%), Positives = 113/263 (42%), Gaps = 6/263 (2%) Frame = +1 Query: 412 GCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 G A + +A+++G + + LL+++ L G R +H+A+ ++ +L Sbjct: 460 GQCAGHTAMQAASQNGHVDVLKLLLKHSVDLEAEDKDGDR--AVHHASFGDEGSVIEVLH 517 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 G ++N RN R QT L A GH +VV+TL+ F + D G T +H A Sbjct: 518 RGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQD-SEGDTPLHDAISKKRD 576 Query: 772 RCLRLVL---ADYVPSIPNFLNQTKH---RSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 L ++L AD + N N H R + +V+ K D G T L Sbjct: 577 DMLSVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTAL 636 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA 1113 H+AALN HVE +LL+ G + +V + T LH A + +LL+ Sbjct: 637 HLAALNNHVEVAELLVHQGNANLDVQNV---------NQQTALHLAVERQHTQIVRLLVR 687 Query: 1114 RGANLAAKNASGSTPLMVAHSWH 1182 A L ++ G TPL A H Sbjct: 688 AEAKLDVQDKDGDTPLHEALRHH 710 Score = 37.7 bits (86), Expect = 0.20 Identities = 35/119 (29%), Positives = 56/119 (47%), Gaps = 23/119 (19%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLL----DLGA-------SVSEVTIED-GTTIDLLGSGS--- 1053 G T + A+ NGHV+ ++LLL DL A +V + D G+ I++L G Sbjct: 464 GHTAMQAASQNGHVDVLKLLLKHSVDLEAEDKDGDRAVHHASFGDEGSVIEVLHRGGADL 523 Query: 1054 --------TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 TPLH A G+ + L+ G + + +++ G TPL A S R+ + +L Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVL 582
>Q15653:IKBB_HUMAN NF-kappa-B inhibitor beta - Homo sapiens (Human)| Length = 356 Score = 74.7 bits (182), Expect = 1e-12 Identities = 73/246 (29%), Positives = 103/246 (41%), Gaps = 20/246 (8%) Frame = +1 Query: 484 LEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL--ESGVE-INLRNYRGQTALMQAC 654 L + P + Y T G ++ LH A H + LL +G E ++L+N GQTAL A Sbjct: 44 LSWAPLVFGYVTEDG-DTALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQTALHLAA 102 Query: 655 QYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLAD-----------Y 801 G V+ L A + + G TA+H A G C R +L Y Sbjct: 103 ILGETSTVEKLYAAGAGLCVAER-RGHTALHLACRVGAHACARALLQPRPRRPREAPDTY 161 Query: 802 VPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKAD------GGLTPLHMAALNGHVE 963 + P+ T H D+D + + +WK G TPLH+A ++ VE Sbjct: 162 LAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVE 221 Query: 964 CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNA 1143 V+LL D GA + + G +PLH A A +LL+ GAN AA+ Sbjct: 222 MVRLLRDAGADLDKPEPT---------CGRSPLHLAVEAQAADVLELLLRAGANPAARMY 272 Query: 1144 SGSTPL 1161 G TPL Sbjct: 273 GGRTPL 278
>Q8VHK1:CSKI2_MOUSE Caskin-2 - Mus musculus (Mouse)| Length = 1201 Score = 74.7 bits (182), Expect = 1e-12 Identities = 68/245 (27%), Positives = 103/245 (42%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G L+ LLE + + G R PLHYAA QG E V LLL + +N + Sbjct: 56 AALGGSLELIALLLEAQATVDIKDSNGMR--PLHYAAWQGRLEPVRLLLRASAAVNAASL 113 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 GQ L A QYGH+EV + L+ +N + L T + A G + +L+L ++ Sbjct: 114 DGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLK-KTPLDLACEFGRLKVAQLLLNSHL 172 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 +++ D ++ TPLH+AA NGH E ++ LL Sbjct: 173 ------CVALLEGEAKDPCDPNY----------------TTPLHLAAKNGHREVIRQLLK 210 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 G ++ T T LH AA G +LL+ G ++ +N T L Sbjct: 211 AGIEINRQT-----------KTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALD 259 Query: 1165 VAHSW 1179 + + + Sbjct: 260 IVNQF 264 Score = 51.2 bits (121), Expect = 2e-05 Identities = 34/103 (33%), Positives = 52/103 (50%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 +N++ G + LH AAL G +E + LLL+ A+V I+D +G PLHYAA Sbjct: 42 INYQDADGFSALHHAALGGSLELIALLLEAQATVD---IKDS-------NGMRPLHYAAW 91 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 G +LL+ A + A + G PL +A + + E+L Sbjct: 92 QGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134 Score = 49.7 bits (117), Expect = 5e-05 Identities = 33/105 (31%), Positives = 52/105 (49%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 V+ K G+ PLH AA G +E V+LLL A+V+ +++ G PLH AA Sbjct: 75 VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLD----------GQIPLHLAAQ 124 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSN 1212 G+ ++L+ +N N TPL +A + R + ++L N Sbjct: 125 YGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLN 169
>Q9Y575:ASB3_HUMAN Ankyrin repeat and SOCS box protein 3 - Homo sapiens (Human)| Length = 518 Score = 74.7 bits (182), Expect = 1e-12 Identities = 67/233 (28%), Positives = 104/233 (44%), Gaps = 9/233 (3%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH AA+QGH +IV +LLE+G + N T L A + G +V++ L+ AN++ + Sbjct: 83 LHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSH 142 Query: 721 YLNGGTAIHFAALHGHARCLRLVLA--------DYVPSIPNFLNQTKHRSSEEVSDADFD 876 + G ++H A+ +A ++L+L D P F+ ++ E +S Sbjct: 143 SMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFV-AAQYGKLESLSILISS 201 Query: 877 DDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGST 1056 VN +A TPL +AA GH +CV+LLL GA ED S Sbjct: 202 GAN----VNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNED--------SWQL 249 Query: 1057 PLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA-HSWHRNSIEEILSN 1212 P+H AA G+ LLI + +P+ A H + +E +L N Sbjct: 250 PIHAAAQMGHTKILDLLIPLTNRACDTGLNKVSPVYSAVFGGHEDCLEILLRN 302 Score = 67.8 bits (164), Expect = 2e-10 Identities = 57/196 (29%), Positives = 93/196 (47%), Gaps = 9/196 (4%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L A +G + R LL++ + + G NS LH A+ Q + EI+ LLL G Sbjct: 116 LFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNS-LHQASFQENAEIIKLLLRKGANKEC 174 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ G T L A QYG E + L+ AN++ L+ T + AA GH +C+ L+L+ Sbjct: 175 QDDFGITPLFVAAQYGKLESLSILISSGANVN-CQALDKATPLFIAAQEGHTKCVELLLS 233 Query: 796 DYV-PSIPNFLNQTK-----HRSSEEVSDADFDDDGLVKMVNWKADGGL---TPLHMAAL 948 P + + N+ H +++ D L+ + N D GL +P++ A Sbjct: 234 SGADPDL--YCNEDSWQLPIHAAAQMGHTKIL--DLLIPLTNRACDTGLNKVSPVYSAVF 289 Query: 949 NGHVECVQLLLDLGAS 996 GH +C+++LL G S Sbjct: 290 GGHEDCLEILLRNGYS 305 Score = 63.5 bits (153), Expect = 3e-09 Identities = 69/260 (26%), Positives = 111/260 (42%), Gaps = 4/260 (1%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE---INL 615 AAR+G+++ R LL+ + G P+H AA E + +L+ + I + Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWM--PIHEAAYHNSVECLQMLINADSSENYIKM 74 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 + + G AL A GHW++VQ L+ A+ + T L T + A +G LRL+L Sbjct: 75 KTFEGFCALHLAASQGHWKIVQILLEAGADPNATT-LEETTPLFLAVENGQIDVLRLLL- 132 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 +H ++ +G M W + LH A+ + E ++L Sbjct: 133 -------------QHGANV---------NGSHSMCGWNS------LHQASFQENAEIIKL 164 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGST 1155 LL GA+ +D G TPL AA G +LI+ GAN+ + +T Sbjct: 165 LLRKGANKE---CQDDF-------GITPLFVAAQYGKLESLSILISSGANVNCQALDKAT 214 Query: 1156 PLMV-AHSWHRNSIEEILSN 1212 PL + A H +E +LS+ Sbjct: 215 PLFIAAQEGHTKCVELLLSS 234 Score = 54.7 bits (130), Expect = 2e-06 Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 32/182 (17%) Frame = +1 Query: 721 YLNGGTAIHFAALHGHARCLRLVL--------ADYVPSIPNFLNQTKHRSSEEVSDADFD 876 Y + + + AA G+ + LR +L AD +P +++ + +S E + Sbjct: 7 YADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMP--IHEAAYHNSVECLQMLIN 64 Query: 877 DDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGT---------T 1029 D + K G LH+AA GH + VQ+LL+ GA + T+E+ T Sbjct: 65 ADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQ 124 Query: 1030 IDLL-----------GS----GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 ID+L GS G LH A+ NA +LL+ +GAN ++ G TPL Sbjct: 125 IDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLF 184 Query: 1165 VA 1170 VA Sbjct: 185 VA 186
>Q25338:LITD_LATMA Delta-latroinsectotoxin precursor - Latrodectus mactans (Black widow| spider) Length = 1214 Score = 74.3 bits (181), Expect = 2e-12 Identities = 77/290 (26%), Positives = 125/290 (43%), Gaps = 33/290 (11%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A R G + R LLE +P + +PLH A + + +LL ++ N ++ Sbjct: 578 ATRSGFSKTVRNLLE-SPNIKVNEKEDDGFTPLHTAVMSTYMVVDALLNHPDIDKNAQST 636 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G T A EV ++L+ NA+++ D +N IHFAA G + LR +++ Sbjct: 637 SGLTPFHLAIINESQEVAESLVESNADLNIQD-VNHMAPIHFAASMGSIKMLRYLISIKD 695 Query: 805 PSIPNFLNQTKH----------RSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNG 954 N + + + + + + DD + +V ADG LT LH+A G Sbjct: 696 KVSINSVTENNNWTPLHFAIYFKKEDAAKELLKQDDINLTIV---ADGNLTVLHLAVSTG 752 Query: 955 HVECVQLLLDLGASVSEVT----------------------IEDGTTIDLLGSGS-TPLH 1065 + ++ LL G+++ E T IE+G I+ + + TPLH Sbjct: 753 QINIIKELLKRGSNIEEKTGEGYTSLHIAAMRKEPEIAVVLIENGADIEARSADNLTPLH 812 Query: 1066 YAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNE 1215 AA G L+ +GA++ AK A GST L +A S + E L N+ Sbjct: 813 SAAKIGRKSTVLYLLEKGADIGAKTADGSTALHLAVSGRKMKTVETLLNK 862 Score = 40.8 bits (94), Expect = 0.023 Identities = 40/167 (23%), Positives = 71/167 (42%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH AA + EI +L+E+G +I R+ T L A + G V L+ A+I Sbjct: 778 LHIAAMRKEPEIAVVLIENGADIEARSADNLTPLHSAAKIGRKSTVLYLLEKGADIGAKT 837 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 +G TA+H A V + ++ LN+ + ++D++ + Sbjct: 838 -ADGSTALHLA-----------VSGRKMKTVETLLNKGANLK-------EYDNNKYL--- 875 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 P+H A +N ++ V+L L+ S+ + E+G T +L Sbjct: 876 ---------PIHKAIINDDLDMVRLFLEKDPSLKDDETEEGRTSIML 913 Score = 40.8 bits (94), Expect = 0.023 Identities = 30/86 (34%), Positives = 40/86 (46%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA G V LLE G +I + G TAL A + V+TL+ AN+ Sbjct: 809 TPLHSAAKIGRKSTVLYLLEKGADIGAKTADGSTALHLAVSGRKMKTVETLLNKGANLKE 868 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVL 792 D N IH A ++ +RL L Sbjct: 869 YDN-NKYLPIHKAIINDDLDMVRLFL 893 Score = 38.1 bits (87), Expect = 0.15 Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 1/92 (1%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 + K G TPLH+AA G V+LL++ GA V+ T + + TPLH A Sbjct: 530 IELKDKNGFTPLHIAAEAGQAGFVKLLINHGADVNAKTSK---------TNLTPLHLATR 580 Query: 1078 GG-NAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G + LL + + K G TPL A Sbjct: 581 SGFSKTVRNLLESPNIKVNEKEDDGFTPLHTA 612
>Q8VHS6:ASB15_MOUSE Ankyrin repeat and SOCS box protein 15 - Mus musculus (Mouse)| Length = 583 Score = 74.3 bits (181), Expect = 2e-12 Identities = 71/259 (27%), Positives = 122/259 (47%), Gaps = 2/259 (0%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L+ A + G AL++YN L + R S +H AA QG +I++LLL ++L Sbjct: 148 LLIAIKRGSYDMVSALIKYNTSLDQPCV--KRWSAMHEAAKQGRKDIITLLLNHRGNVHL 205 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 R+ G T L A +YGH +V++ L+ ++ +G + + AA G+ C+ L+L Sbjct: 206 RDGFGVTPLGVAAEYGHCDVLEHLIHKGGDVFALAD-DGASVLFEAAGGGNPDCISLLLK 264 Query: 796 -DYVPSIPNFLNQTK-HRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 ++PN HR++ E V + GLTP+H AA + +C+ Sbjct: 265 YGGSGNVPNRAGHLPIHRAAYEGHYLALKYLIPVTSKHAIQKSGLTPIHSAAEGQNAQCL 324 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 +LL++ G V + + D + T L++A + C ++L+A GA+ N Sbjct: 325 ELLIENGFDV-KALLADHISQSYDDERKTALYFAVSNNDIHCTEVLLAAGAD---PNLDP 380 Query: 1150 STPLMVAHSWHRNSIEEIL 1206 L+VA +R+ I +L Sbjct: 381 LNCLLVAVRANRHEIVRLL 399 Score = 63.9 bits (154), Expect = 3e-09 Identities = 56/209 (26%), Positives = 90/209 (43%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PL A G E V LL+ GV N +N +G+T L+ A + G +++V L+ +N ++ + Sbjct: 113 TPLTLAVKAGLVENVKTLLDKGVWPNTKNDKGETPLLIAIKRGSYDMVSALIKYNTSLDQ 172 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + +A+H AA G + L+L HR + + D Sbjct: 173 -PCVKRWSAMHEAAKQGRKDIITLLL--------------NHRGNVHLRDG--------- 208 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 G+TPL +AA GH + ++ L+ G G L G++ L AA Sbjct: 209 -------FGVTPLGVAAEYGHCDVLEHLIHKG----------GDVFALADDGASVLFEAA 251 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL 1161 GGN C LL+ G + N +G P+ Sbjct: 252 GGGNPDCISLLLKYGGSGNVPNRAGHLPI 280 Score = 34.3 bits (77), Expect = 2.2 Identities = 27/84 (32%), Positives = 38/84 (45%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 G PLH A V+ +Q +L+ S T+ + T D G TPL A G Sbjct: 76 GWFPLHEAV----VQPIQQILETVLDASYKTLWEFKTCD----GETPLTLAVKAGLVENV 127 Query: 1099 QLLIARGANLAAKNASGSTPLMVA 1170 + L+ +G KN G TPL++A Sbjct: 128 KTLLDKGVWPNTKNDKGETPLLIA 151
>Q8N6D5:ANR29_HUMAN Ankyrin repeat domain-containing protein 29 - Homo sapiens (Human)| Length = 301 Score = 74.3 bits (181), Expect = 2e-12 Identities = 69/228 (30%), Positives = 111/228 (48%), Gaps = 2/228 (0%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH-RT 717 L AA GH + V L+ G +INL+ G TAL A Q GH +VV+ L F A+ RT Sbjct: 50 LMVAAYAGHIDCVRELVLQGADINLQRESGTTALFFAAQQGHNDVVRFLFGFGASTEFRT 109 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM 897 +GGTA+ A+ +GH + + +L KH ++ + D +D Sbjct: 110 K--DGGTALLAASQYGHMQVVETLL--------------KHGAN--IHDQLYD------- 144 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 G T L +AA G+++ ++LLL GA V++ +DGT PL A+ Sbjct: 145 -------GATALFLAAQGGYLDVIRLLLASGAKVNQPR-QDGT---------APLWIASQ 187 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLM-VAHSWHRNSIEEILSNEP 1218 G++ ++++ RGA+ A G+T L+ A+ + + I+E+L P Sbjct: 188 MGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYNDVIKELLKFSP 235 Score = 54.3 bits (129), Expect = 2e-06 Identities = 41/133 (30%), Positives = 69/133 (51%), Gaps = 1/133 (0%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA+ G L R LL ++ + G +PL A+ GH E+V ++L G + + Sbjct: 149 LFLAAQGGYLDVIRLLLASGAKVNQPRQDG--TAPLWIASQMGHSEVVRVMLLRGADRDA 206 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL- 792 G TAL++A G+ +V++ L+ F+ + NG +A+H A L G+ + + L+L Sbjct: 207 ARNDGTTALLKAANKGYNDVIKELLKFSPTLGILK--NGTSALHAAVLSGNIKTVALLLE 264 Query: 793 ADYVPSIPNFLNQ 831 A PS+ N N+ Sbjct: 265 AGADPSLRNKANE 277 Score = 40.0 bits (92), Expect = 0.039 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 1/106 (0%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 V+ + G T L +AA GH++CV+ L+ GA ++ SG+T L +AA Sbjct: 39 VDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQR----------ESGTTALFFAAQ 88 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW-HRNSIEEILSN 1212 G+ + L GA+ + G T L+ A + H +E +L + Sbjct: 89 QGHNDVVRFLFGFGASTEFRTKDGGTALLAASQYGHMQVVETLLKH 134 Score = 34.3 bits (77), Expect = 2.2 Identities = 25/89 (28%), Positives = 41/89 (46%) Frame = +1 Query: 940 AALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG 1119 AA G++ ++LLL+ G + GTT+ L AA G+ C + L+ +G Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCRDSHGTTL---------LMVAAYAGHIDCVRELVLQG 69 Query: 1120 ANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 A++ + SG+T L A N + L Sbjct: 70 ADINLQRESGTTALFFAAQQGHNDVVRFL 98
>Q9P0K7:RAI14_HUMAN Ankycorbin - Homo sapiens (Human)| Length = 980 Score = 73.9 bits (180), Expect = 2e-12 Identities = 66/259 (25%), Positives = 111/259 (42%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 +RL+ A +GD ++ +LL A G+ + H AAA+GH E + +++ GV++ Sbjct: 21 DRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTA-FHLAAAKGHVECLRVMITHGVDV 79 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 ++ G +AL A + H E ++ L+ D +G TA+H+AA G + ++++ Sbjct: 80 TAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVD-SSGKTALHYAAAQGCLQAVQIL 138 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 +H+S + D D G PL +A NGH E Sbjct: 139 --------------CEHKSPINLKDLD----------------GNIPLLLAVQNGHSEIC 168 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 LLD GA V+ SG T L A G++ + LI +GA+L ++ G Sbjct: 169 HFLLDHGADVNSRN----------KSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLG 218 Query: 1150 STPLMVAHSWHRNSIEEIL 1206 L + I+ +L Sbjct: 219 YNALHYSKLSENAGIQSLL 237 Score = 66.6 bits (161), Expect = 4e-10 Identities = 48/150 (32%), Positives = 73/150 (48%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G LQ + L E+ + G N PL A GH EI LL+ G ++N RN Sbjct: 126 AAAQGCLQAVQILCEHKSPINLKDLDG--NIPLLLAVQNGHSEICHFLLDHGADVNSRNK 183 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G+TALM AC+ G V+ L+ A+++ D L G A+H++ L +A L+L+ + Sbjct: 184 SGRTALMLACEIGSSNAVEALIKKGADLNLVDSL-GYNALHYSKLSENAGIQSLLLSK-I 241 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + TK + ++VS + G K Sbjct: 242 SQDADLKTPTKPKQHDQVSKISSERSGTPK 271
>Q68DC2:ANKS6_HUMAN Ankyrin repeat and SAM domain-containing protein 6 - Homo sapiens| (Human) Length = 871 Score = 73.9 bits (180), Expect = 2e-12 Identities = 60/198 (30%), Positives = 94/198 (47%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 N+ L +AAA GH +V LL G +N RN+ G +ALMQA ++GH V L+ A+++ Sbjct: 79 NTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADVN 138 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 + L G + + A+ GH ++L+L F++ H S E++ D+ L Sbjct: 139 AQNRL-GASVLTVASRGGHLGVVKLLL-----EAGAFVDH-HHPSGEQLGLGGSRDEPL- 190 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYA 1071 +T L A +GH V+LL++ GA + T+ G +PL A Sbjct: 191 ---------DITALMAAIQHGHEAVVRLLMEWGADPNHA----ARTV-----GWSPLMLA 232 Query: 1072 ACGGNAVCCQLLIARGAN 1125 A G Q L+ +GAN Sbjct: 233 ALTGRLGVAQQLVEKGAN 250 Score = 64.7 bits (156), Expect = 1e-09 Identities = 79/306 (25%), Positives = 123/306 (40%), Gaps = 55/306 (17%) Frame = +1 Query: 403 NSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVS 582 N +G SA L+ AAR G + A LL++ + + G S L A+ GH +V Sbjct: 108 NHYGWSA----LMQAARFGHVSVAHLLLDHGADVNAQNRLGA--SVLTVASRGGHLGVVK 161 Query: 583 LLLESGVEINLRNYRGQ--------------TALMQACQYGHWEVVQTLMLFNANIHRTD 720 LLLE+G ++ + G+ TALM A Q+GH VV+ LM + A+ + Sbjct: 162 LLLEAGAFVDHHHPSGEQLGLGGSRDEPLDITALMAAIQHGHEAVVRLLMEWGADPNHAA 221 Query: 721 YLNGGTAIHFAALHGHAR----------------------------CLRLVLADYVPSI- 813 G + + AAL G C L DY+ + Sbjct: 222 RTVGWSPLMLAALTGRLGVAQQLVEKGANPDHLSVLEKTAFEVALDCKHRDLVDYLDPLT 281 Query: 814 ------------PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGH 957 P+ + K + + V + +D V +VN G TPL +AA+ G Sbjct: 282 TVRPKTDEEKRRPDIFHALKMGNFQLVKEIADEDPSHVNLVN---GDGATPLMLAAVTGQ 338 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 + VQLL++ A V + +D G T L A GN + L+ +GA++ + Sbjct: 339 LALVQLLVERHADVDK---QDSV------HGWTALMQATYHGNKEIVKYLLNQGADVTLR 389 Query: 1138 NASGST 1155 +G T Sbjct: 390 AKNGYT 395 Score = 37.4 bits (85), Expect = 0.26 Identities = 49/162 (30%), Positives = 70/162 (43%), Gaps = 15/162 (9%) Frame = +1 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRS-SEEVSDADFDDDGLVKM--- 897 G TA+ FAA GH +R +L +N H S + A F + + Sbjct: 78 GNTALQFAAAGGHEPLVRFLLRRGAS-----VNSRNHYGWSALMQAARFGHVSVAHLLLD 132 Query: 898 ----VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLH 1065 VN + G + L +A+ GH+ V+LLL+ GA V G + L GS PL Sbjct: 133 HGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDH-HHPSGEQLGLGGSRDEPLD 191 Query: 1066 YAAC-----GGNAVCCQLLIARGA--NLAAKNASGSTPLMVA 1170 A G+ +LL+ GA N AA+ G +PLM+A Sbjct: 192 ITALMAAIQHGHEAVVRLLMEWGADPNHAARTV-GWSPLMLA 232 Score = 37.0 bits (84), Expect = 0.33 Identities = 30/91 (32%), Positives = 42/91 (46%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 V+ + G T L AA GH V+ LL GASV+ G + L AA Sbjct: 71 VDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRN----------HYGWSALMQAAR 120 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 G+ LL+ GA++ A+N G++ L VA Sbjct: 121 FGHVSVAHLLLDHGADVNAQNRLGASVLTVA 151 Score = 35.4 bits (80), Expect = 0.97 Identities = 18/54 (33%), Positives = 32/54 (59%) Frame = +1 Query: 1045 SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 +G+T L +AA GG+ + L+ RGA++ ++N G + LM A + S+ +L Sbjct: 77 AGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLL 130
>Q6GNY1:MIB1_XENLA E3 ubiquitin-protein ligase mib1 - Xenopus laevis (African clawed| frog) Length = 1011 Score = 73.6 bits (179), Expect = 3e-12 Identities = 74/283 (26%), Positives = 124/283 (43%), Gaps = 8/283 (2%) Frame = +1 Query: 412 GCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 G A + +A+++G + + LL+++ + G R +H+AA ++ +L Sbjct: 460 GQCAGHTAMQAASQNGHVDILKLLLKHSVDVEAEDKDGDR--AVHHAAFGDEGTVIEVLQ 517 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 G ++N RN R QT L A GH +VV+ L+ F+ + D G T +H A Sbjct: 518 RGGADLNARNKRRQTPLHIAVNKGHLQVVKKLLDFSCHPSLQD-SEGDTPLHDAISKKRD 576 Query: 772 RCLRLVL---ADYVPSIPNFLNQTKH---RSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 L ++L AD + N N H R + +V+ K D G T L Sbjct: 577 DILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTAL 636 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLG-SGSTPLHYAACGGNAVCCQLLI 1110 H+AALN HVE +LL+ G++ +D+ + T LH A + +LL+ Sbjct: 637 HLAALNNHVEVAELLVHQGSA----------NLDIQNVNQQTALHLAVERQHTQIVRLLV 686 Query: 1111 ARGANLAAKNASGSTPLMVAHSWHR-NSIEEILSNEPGGQIRT 1236 A L ++ G TPL A H + + ++ + G++ T Sbjct: 687 RAEAKLDIQDKDGDTPLHEALRHHTLSQLRQLQDMQDVGKVDT 729
>Q28BK1:HACE1_XENTR E3 ubiquitin-protein ligase HACE1 - Xenopus tropicalis (Western| clawed frog) (Silurana tropicalis) Length = 912 Score = 73.6 bits (179), Expect = 3e-12 Identities = 65/212 (30%), Positives = 96/212 (45%), Gaps = 1/212 (0%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + S LH AA G E + LLL+ G + N ++ G T L A + G + + L+ +NA++ Sbjct: 65 KRSLLHIAANCGSVECLVLLLKRGADPNYQDISGCTPLHLAARNGQKKCMSKLLEYNADV 124 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + + G TAIH+ A++G L H + V++ D +D Sbjct: 125 NICNN-EGLTAIHWLAVNGRTELL-------------------HDLVQHVTNVDVED--- 161 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 G T LH+A NGH V LLD GA ++ + SG+TPL++ Sbjct: 162 --------AMGQTALHVACQNGHKTTVLCLLDSGADINRPNV----------SGATPLYF 203 Query: 1069 AACGGNAVCCQLLIARGAN-LAAKNASGSTPL 1161 A G Q+L+ RGA L KN G TPL Sbjct: 204 ACSHGQRDTAQILLLRGAKYLPDKN--GVTPL 233 Score = 58.5 bits (140), Expect = 1e-07 Identities = 42/124 (33%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AAR+G + LLEYN + + G + +H+ A G E++ L++ +++ + Sbjct: 105 AARNGQKKCMSKLLEYNADVNICNNEG--LTAIHWLAVNGRTELLHDLVQHVTNVDVEDA 162 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGH---ARCLRLVLA 795 GQTAL ACQ GH V L+ A+I+R + ++G T ++FA HG A+ L L A Sbjct: 163 MGQTALHVACQNGHKTTVLCLLDSGADINRPN-VSGATPLYFACSHGQRDTAQILLLRGA 221 Query: 796 DYVP 807 Y+P Sbjct: 222 KYLP 225 Score = 55.8 bits (133), Expect = 7e-07 Identities = 55/192 (28%), Positives = 78/192 (40%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA G + +S LLE ++N+ N G TA+ G E++ L+ N+ Sbjct: 100 TPLHLAARNGQKKCMSKLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTNVDV 159 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 D + G TA+H A +GH + L L D S AD Sbjct: 160 EDAM-GQTALHVACQNGHKTTV-LCLLD--------------------SGAD-------- 189 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 +N G TPL+ A +G + Q+LL GA + D +G TPL Sbjct: 190 -INRPNVSGATPLYFACSHGQRDTAQILLLRGAKY----LPD-------KNGVTPLDLCV 237 Query: 1075 CGGNAVCCQLLI 1110 GG C +LI Sbjct: 238 QGGYGETCDILI 249 Score = 51.6 bits (122), Expect = 1e-05 Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 23/125 (18%) Frame = +1 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL------------- 1041 N++ G TPLH+AA NG +C+ LL+ A V+ E T I L Sbjct: 92 NYQDISGCTPLHLAARNGQKKCMSKLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLV 151 Query: 1042 ----------GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS 1191 G T LH A G+ L+ GA++ N SG+TPL A S + Sbjct: 152 QHVTNVDVEDAMGQTALHVACQNGHKTTVLCLLDSGADINRPNVSGATPLYFACSHGQRD 211 Query: 1192 IEEIL 1206 +IL Sbjct: 212 TAQIL 216 Score = 45.8 bits (107), Expect = 7e-04 Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 3/108 (2%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A GH V LL+SG +IN N G T L AC +G + Q L+L A Sbjct: 168 LHVACQNGHKTTVLCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAK----- 222 Query: 721 YL---NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEE 855 YL NG T + G+ +++ + + T++ E Sbjct: 223 YLPDKNGVTPLDLCVQGGYGETCDILIQHHPRLFQTLIQMTQNEDLRE 270
>Q6DCL5:HACE1_XENLA E3 ubiquitin-protein ligase HACE1 - Xenopus laevis (African clawed| frog) Length = 944 Score = 73.6 bits (179), Expect = 3e-12 Identities = 65/212 (30%), Positives = 96/212 (45%), Gaps = 1/212 (0%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + S LH AA G E + LLL+ G + N ++ G T L A + G + + L+ +NA++ Sbjct: 65 KRSLLHIAANCGSVECLVLLLKRGADPNYQDISGCTPLHLAARNGQKKCMSKLLEYNADV 124 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + + G TAIH+ A++G L H + V++ D +D Sbjct: 125 NICNN-EGLTAIHWLAVNGRTELL-------------------HDLVQHVTNVDVED--- 161 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 G T LH+A NGH V LLD GA ++ + SG+TPL++ Sbjct: 162 --------AMGQTALHVACQNGHKTTVLCLLDSGADINRPNV----------SGATPLYF 203 Query: 1069 AACGGNAVCCQLLIARGAN-LAAKNASGSTPL 1161 A G Q+L+ RGA L KN G TPL Sbjct: 204 ACSHGQRDTAQILLLRGAKYLPDKN--GVTPL 233 Score = 58.5 bits (140), Expect = 1e-07 Identities = 42/124 (33%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AAR+G + LLEYN + + G + +H+ A G E++ L++ +++ + Sbjct: 105 AARNGQKKCMSKLLEYNADVNICNNEG--LTAIHWLAVNGRTELLHDLVQHVTNVDVEDA 162 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGH---ARCLRLVLA 795 GQTAL ACQ GH V L+ A+I+R + ++G T ++FA HG A+ L L A Sbjct: 163 MGQTALHVACQNGHKTTVLCLLDSGADINRPN-VSGATPLYFACSHGQRDTAQILLLRGA 221 Query: 796 DYVP 807 Y+P Sbjct: 222 KYLP 225 Score = 55.8 bits (133), Expect = 7e-07 Identities = 55/192 (28%), Positives = 78/192 (40%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA G + +S LLE ++N+ N G TA+ G E++ L+ N+ Sbjct: 100 TPLHLAARNGQKKCMSKLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTNVDV 159 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 D + G TA+H A +GH + L L D S AD Sbjct: 160 EDAM-GQTALHVACQNGHKTTV-LCLLD--------------------SGAD-------- 189 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 +N G TPL+ A +G + Q+LL GA + D +G TPL Sbjct: 190 -INRPNVSGATPLYFACSHGQRDTAQILLLRGAKY----LPD-------KNGVTPLDLCV 237 Query: 1075 CGGNAVCCQLLI 1110 GG C +LI Sbjct: 238 QGGYGETCDILI 249 Score = 51.6 bits (122), Expect = 1e-05 Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 23/125 (18%) Frame = +1 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL------------- 1041 N++ G TPLH+AA NG +C+ LL+ A V+ E T I L Sbjct: 92 NYQDISGCTPLHLAARNGQKKCMSKLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLV 151 Query: 1042 ----------GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS 1191 G T LH A G+ L+ GA++ N SG+TPL A S + Sbjct: 152 QHVTNVDVEDAMGQTALHVACQNGHKTTVLCLLDSGADINRPNVSGATPLYFACSHGQRD 211 Query: 1192 IEEIL 1206 +IL Sbjct: 212 TAQIL 216 Score = 45.8 bits (107), Expect = 7e-04 Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 3/108 (2%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A GH V LL+SG +IN N G T L AC +G + Q L+L A Sbjct: 168 LHVACQNGHKTTVLCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAK----- 222 Query: 721 YL---NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEE 855 YL NG T + G+ +++ + + T++ E Sbjct: 223 YLPDKNGVTPLDLCVQGGYGETCDILIQHHPRLFQTLIQMTQNEELRE 270
>Q7Z8U2:AKR1_ASPOR Palmitoyltransferase akr1 - Aspergillus oryzae| Length = 737 Score = 73.6 bits (179), Expect = 3e-12 Identities = 73/258 (28%), Positives = 110/258 (42%), Gaps = 1/258 (0%) Frame = +1 Query: 400 GNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIV 579 G + G GE ++ AR G++ + L + A + G +PLH+AA + + Sbjct: 55 GAARGSIPLGEDIMQIARIGEVPAMQRLFDEKKFSANHKDEEGI-TPLHWAAINNQYAMC 113 Query: 580 SLLLESGVEINLRNYRG-QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAA 756 LL+SG ++N + T M A Q H+ +V L+ A+ TD + G +H A Sbjct: 114 KFLLDSGADVNAKGGESVATPAMWAAQRCHYYIVHLLLQRGADPLLTD-VQGYNILHLAT 172 Query: 757 LHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLH 936 + G+A L L+L +P V +V+ + G T L Sbjct: 173 IDGNAFLLVLLLHQEIP---------------------------VDVVDQQ---GHTGLM 202 Query: 937 MAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIAR 1116 AA G+ V L L GA + V ++G G TPLH+A G+ C LI Sbjct: 203 WAAYKGYPALVDLFLRWGAHANAV--DEG--------GLTPLHWALVKGSLPCVLKLIEY 252 Query: 1117 GANLAAKNASGSTPLMVA 1170 GA+ AK G TP +VA Sbjct: 253 GADKFAKTRDGKTPAVVA 270
>Q8N9B4:ANR42_HUMAN Ankyrin repeat domain-containing protein 42 - Homo sapiens (Human)| Length = 389 Score = 73.2 bits (178), Expect = 4e-12 Identities = 55/207 (26%), Positives = 92/207 (44%), Gaps = 44/207 (21%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA GH + ++L SGV+ ++ + R + A +G +Q L+ + +I Sbjct: 100 TPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIED 159 Query: 715 TDYLNGGTAIHFAALHGHARCLRL----------VLADYVPSIPNFLNQT----KHRSSE 852 DY NG +H AA+ GH C + VL + + N L+ K + Sbjct: 160 VDY-NGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQ 218 Query: 853 EVSDADFD------------------------------DDGLVKMVNWKADGGLTPLHMA 942 + A+++ +DG++ +N +AD G TP+H A Sbjct: 219 FIQGAEYEGKDLEDQETLAFPGHVAAFKGDLGMLKKLVEDGVIN-INERADNGSTPMHKA 277 Query: 943 ALNGHVECVQLLLDLGASVSEVTIEDG 1023 A GH+EC+Q L+ +GA S +T + G Sbjct: 278 AGQGHIECLQWLIKMGAD-SNITNKAG 303 Score = 66.6 bits (161), Expect = 4e-10 Identities = 65/244 (26%), Positives = 103/244 (42%), Gaps = 6/244 (2%) Frame = +1 Query: 493 NPRLARYSTFGGRNSPLHYAAAQGHHEIVSL--LLESGVEINLRNYRGQTALMQACQYGH 666 NP + FG + + + EIV L LL G +I RG TA A G Sbjct: 18 NPCSRKKVHFGSIHDAVRAGDVKQLSEIVCLHWLLWHGADITHVTTRGWTASHIAAIRGQ 77 Query: 667 WEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRS 846 VQ L++ AN+ D G T +H AA HGH+ L+++L V Sbjct: 78 DACVQALIMNGANLTAQDD-RGCTPLHLAATHGHSFTLQIMLRSGV-------------- 122 Query: 847 SEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGT 1026 D + W+ P+H AA +G + C+QLL+ G S+ +V Sbjct: 123 ----------DPSVTDKREWR------PVHYAAFHGRLGCLQLLVKWGCSIEDVDY---- 162 Query: 1027 TIDLLGSGSTPLHYAACGGNAVCCQLLIARGAN----LAAKNASGSTPLMVAHSWHRNSI 1194 +G+ P+H AA G+ C + L++R ++ L A N +G L +A + + +I Sbjct: 163 ------NGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNI 216 Query: 1195 EEIL 1206 + + Sbjct: 217 LQFI 220 Score = 37.7 bits (86), Expect = 0.20 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 5/86 (5%) Frame = +1 Query: 445 AARDGDLQEARALLE-----YNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 AA GDL + L+E N R ST P+H AA QGH E + L++ G + Sbjct: 243 AAFKGDLGMLKKLVEDGVININERADNGST------PMHKAAGQGHIECLQWLIKMGADS 296 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTL 687 N+ N G+ A ++ H V+ L Sbjct: 297 NITNKAGERPSDVAKRFAHLAAVKLL 322
>P20749:BCL3_HUMAN B-cell lymphoma 3-encoded protein - Homo sapiens (Human)| Length = 446 Score = 72.8 bits (177), Expect = 5e-12 Identities = 76/267 (28%), Positives = 109/267 (40%), Gaps = 28/267 (10%) Frame = +1 Query: 532 NSPLHYAAAQGH----HEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 ++PLH A QG+ H +V+L + G E+++ N QT L A VV+ L+ Sbjct: 128 DTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLVTAG 187 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 A+ D +G TA H A H CLR +L P + ++ ++D Sbjct: 188 ASPMALDR-HGQTAAHLACEHRSPTCLRALLDSAAP------------GTLDLEARNYD- 233 Query: 880 DGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDG------------ 1023 GLT LH+A E VQLLL+ GA + V I+ G Sbjct: 234 -------------GLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNS 280 Query: 1024 -TTIDLL-----------GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMV 1167 + + LL SGS+ LH A+ G + L+ GA+ + KN TPLMV Sbjct: 281 LSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMV 340 Query: 1168 AHSWHRNSIEEILSNEPGGQIRTLPSP 1248 A S I + P + PSP Sbjct: 341 ARSRRVIDILRGKATRPASTSQPDPSP 367 Score = 36.2 bits (82), Expect = 0.57 Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 1/112 (0%) Frame = +1 Query: 373 ASMGFLSLVGNSFGCSASGERLVSAARDGDLQEA-RALLEYNPRLARYSTFGGRNSPLHY 549 A+ G L L ++ G + A + + QE + LLE + GR SPL + Sbjct: 220 AAPGTLDLEARNY----DGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGR-SPLIH 274 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN 705 A +V LLL+ G +N + Y G +AL A G +V+TL+ A+ Sbjct: 275 AVENNSLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGAD 326 Score = 34.3 bits (77), Expect = 2.2 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 1/95 (1%) Frame = +1 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS-GSTPLH 1065 + M + G TPLH+A + G++ V L++L + G +D+ + TPLH Sbjct: 117 IAMATRADEDGDTPLHIAVVQGNLPAVHRLVNLFQ-------QGGRELDIYNNLRQTPLH 169 Query: 1066 YAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 A +LL+ GA+ A + G T +A Sbjct: 170 LAVITTLPSVVRLLVTAGASPMALDRHGQTAAHLA 204
>P0C0T2:ANKS6_RAT Ankyrin repeat and SAM domain-containing protein 6 - Rattus| norvegicus (Rat) Length = 885 Score = 72.8 bits (177), Expect = 5e-12 Identities = 76/264 (28%), Positives = 108/264 (40%), Gaps = 26/264 (9%) Frame = +1 Query: 412 GCSASG-ERLVSAARDGDLQEARALLE---------------YNPRLARYSTFG------ 525 G A G + L+ A GD AR LLE P AR G Sbjct: 4 GALAPGLQLLLRACEQGDTDTARRLLEPGGEPVAGSEAGAEPAGPEAARAVEAGTPVPVD 63 Query: 526 ----GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML 693 NS L AAA GH +V LL G +N RN+ G +ALMQA + GH V L+ Sbjct: 64 CSDEAGNSALQLAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARCGHASVAHLLLD 123 Query: 694 FNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADF 873 A+++ + L G + + A+ GH ++L+L ++ S E + Sbjct: 124 HGADVNAQNRL-GASVLTVASRGGHLGVVKLLLE------AGATVDHRNPSGESTASGGS 176 Query: 874 DDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS 1053 D+ L G+T L A +GH V+LL++ GA + T+ G Sbjct: 177 RDELL----------GITALMAAVQHGHEAVVRLLMEWGADPNHT----ARTV-----GW 217 Query: 1054 TPLHYAACGGNAVCCQLLIARGAN 1125 +PL AA G Q L+ +GAN Sbjct: 218 SPLMLAALLGKLSVVQQLVEKGAN 241 Score = 70.1 bits (170), Expect = 4e-11 Identities = 81/306 (26%), Positives = 128/306 (41%), Gaps = 55/306 (17%) Frame = +1 Query: 403 NSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVS 582 N +G SA L+ AAR G A LL++ + + G S L A+ GH +V Sbjct: 99 NHYGWSA----LMQAARCGHASVAHLLLDHGADVNAQNRLGA--SVLTVASRGGHLGVVK 152 Query: 583 LLLESGVEINLRNYRGQ--------------TALMQACQYGHWEVVQTLMLFNANIHRTD 720 LLLE+G ++ RN G+ TALM A Q+GH VV+ LM + A+ + T Sbjct: 153 LLLEAGATVDHRNPSGESTASGGSRDELLGITALMAAVQHGHEAVVRLLMEWGADPNHTA 212 Query: 721 YLNGGTAIHFAALHGHARCLRLV----------------------------LADYVPSI- 813 G + + AAL G ++ + LADY+ + Sbjct: 213 RTVGWSPLMLAALLGKLSVVQQLVEKGANPDHLGVLEKTAFEVALDRKHRDLADYLDPLT 272 Query: 814 ------------PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGH 957 P+ + K + + V + +D V +VN G TPL +AA+ G Sbjct: 273 TVRPKTDEEKRRPDIFHALKMGNFQLVKEIADEDPNHVNLVN---GDGATPLMLAAVTGQ 329 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 + VQLL++ A +++ +D G T L A GN + L+ +GA++ + Sbjct: 330 LPLVQLLVEKHADMNK---QDSV------HGWTALMQATYHGNKEIVKYLLNQGADVTLR 380 Query: 1138 NASGST 1155 +G T Sbjct: 381 AKNGYT 386
>Q96I34:PP16A_HUMAN Protein phosphatase 1 regulatory subunit 16A - Homo sapiens (Human)| Length = 528 Score = 72.4 bits (176), Expect = 7e-12 Identities = 74/251 (29%), Positives = 104/251 (41%), Gaps = 7/251 (2%) Frame = +1 Query: 436 LVSAARDGDLQEARALLE--YNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 L+ AA DL+E R L +P LA + LH E+V LLE+G I Sbjct: 75 LLEAAARNDLEEVRQFLGSGVSPDLANEDGL----TALHQCCIDDFREMVQQLLEAGANI 130 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 N + T L A GH +V+ L+ AN+ + +G CL Sbjct: 131 NACDSECWTPLHAAATCGHLHLVELLIASGANLLAVN-TDGNMPYDLCDDEQTLDCLETA 189 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM-----VNWKADGGLTPLHMAALNG 954 +AD + Q ++ V + DD ++ ++ D G T LH+AA NG Sbjct: 190 MAD------RGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANG 243 Query: 955 HVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAA 1134 E LLL+ AS+S + G PLH AA G +LL+A GA+L A Sbjct: 244 FSEAAALLLEHRASLSAKDQD----------GWEPLHAAAYWGQVPLVELLVAHGADLNA 293 Query: 1135 KNASGSTPLMV 1167 K+ TPL V Sbjct: 294 KSLMDETPLDV 304
>Q8WXE0:CSKI2_HUMAN Caskin-2 - Homo sapiens (Human)| Length = 1202 Score = 72.4 bits (176), Expect = 7e-12 Identities = 67/245 (27%), Positives = 102/245 (41%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G L+ LLE + + G R PLHYAA QG E V LLL + +N + Sbjct: 56 AALGGSLELIALLLEAQATVDIKDSNGMR--PLHYAAWQGRLEPVRLLLRASAAVNAASL 113 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 GQ L A QYGH+EV + L+ +N + T + A G + +L+L ++ Sbjct: 114 DGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAK-KTPLDLACEFGRLKVAQLLLNSHL 172 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 +++ D ++ TPLH+AA NGH E ++ LL Sbjct: 173 ------CVALLEGEAKDPCDPNY----------------TTPLHLAAKNGHREVIRQLLR 210 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 G ++ T T LH AA G +LL+ G ++ +N T L Sbjct: 211 AGIEINRQT-----------KTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALD 259 Query: 1165 VAHSW 1179 + + + Sbjct: 260 IVNQF 264 Score = 51.6 bits (122), Expect = 1e-05 Identities = 35/103 (33%), Positives = 52/103 (50%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 VN++ G + LH AAL G +E + LLL+ A+V I+D +G PLHYAA Sbjct: 42 VNYQDADGFSALHHAALGGSLELIALLLEAQATVD---IKDS-------NGMRPLHYAAW 91 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 G +LL+ A + A + G PL +A + + E+L Sbjct: 92 QGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134 Score = 50.8 bits (120), Expect = 2e-05 Identities = 33/105 (31%), Positives = 53/105 (50%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 V+ K G+ PLH AA G +E V+LLL A+V+ +++ G PLH AA Sbjct: 75 VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLD----------GQIPLHLAAQ 124 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSN 1212 G+ ++L+ +N N + TPL +A + R + ++L N Sbjct: 125 YGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLN 169
>Q96NW4:ANR27_HUMAN Ankyrin repeat domain-containing protein 27 - Homo sapiens (Human)| Length = 1050 Score = 72.0 bits (175), Expect = 9e-12 Identities = 68/242 (28%), Positives = 97/242 (40%), Gaps = 40/242 (16%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNP--------------------------------RLARY 513 E+L+ A DGDL+ R LLE+ RLA+ Sbjct: 671 EKLLRAVADGDLEMVRYLLEWTEEDLEDAEDTVSAADPEFCHPLCQCPKCAPAQKRLAKV 730 Query: 514 STFG--------GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHW 669 G +SPLH AA G +++ LLL+ G RN L ACQ GH+ Sbjct: 731 PASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHF 790 Query: 670 EVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSS 849 +VV+ L+ NA ++ D L+G T + +A GH + L+L +H +S Sbjct: 791 QVVKCLLDSNAKPNKKD-LSGNTPLIYACSGGHHELVALLL--------------QHGAS 835 Query: 850 EEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTT 1029 +N + G T LH A + HV V+LLL GASV + T Sbjct: 836 ----------------INASNNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTA 879 Query: 1030 ID 1035 +D Sbjct: 880 VD 881 Score = 66.2 bits (160), Expect = 5e-10 Identities = 46/155 (29%), Positives = 68/155 (43%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 ++PLH AA G ++ LL+ G +N +Y G T L ACQ G+ V L+ + A+ Sbjct: 464 HTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAE 523 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 D NG T +H A +GH C++ ++ V S + K Sbjct: 524 VQDN-NGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEK------------------ 564 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGAS 996 G TPLH+AA G+ ++ LL GAS Sbjct: 565 ---------GDTPLHIAARWGYQGVIETLLQNGAS 590 Score = 56.6 bits (135), Expect = 4e-07 Identities = 43/145 (29%), Positives = 63/145 (43%) Frame = +1 Query: 727 NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNW 906 +G + +H AALHG A + L+L KH ++ +AD Sbjct: 743 DGSSPLHVAALHGRADLIPLLL--------------KHGANAGARNAD------------ 776 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 PLH+A GH + V+ LLD A ++ + SG+TPL YA GG+ Sbjct: 777 ----QAVPLHLACQQGHFQVVKCLLDSNAKPNKKDL----------SGNTPLIYACSGGH 822 Query: 1087 AVCCQLLIARGANLAAKNASGSTPL 1161 LL+ GA++ A N G+T L Sbjct: 823 HELVALLLQHGASINASNNKGNTAL 847 Score = 53.9 bits (128), Expect = 3e-06 Identities = 43/153 (28%), Positives = 62/153 (40%), Gaps = 29/153 (18%) Frame = +1 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL----------------- 1041 D G TPLH+AA+ G + LL+ GA V+ T + L Sbjct: 461 DRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKA 520 Query: 1042 ------GSGSTPLHYAACGGNAVCCQLLI---ARGANLAAKNASGSTPLMVAHSW-HRNS 1191 +G+TPLH A G+ C + L+ L N G TPL +A W ++ Sbjct: 521 SAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGV 580 Query: 1192 IEEILSNEPGGQI--RTLPSPYLCLPLMSIMSI 1284 IE +L N +I R +P C I+S+ Sbjct: 581 IETLLQNGASTEIQNRLKETPLKCALNSKILSV 613 Score = 51.6 bits (122), Expect = 1e-05 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 3/103 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH A +G+ + LLL +++ G T L AC YGH + V+ L+ ++ R Sbjct: 498 TPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCR 557 Query: 715 TDYLN--GGTAIHFAALHGHARCLRLVLADYVPS-IPNFLNQT 834 D N G T +H AA G+ + +L + + I N L +T Sbjct: 558 LDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKET 600 Score = 39.7 bits (91), Expect = 0.051 Identities = 20/41 (48%), Positives = 25/41 (60%) Frame = +1 Query: 1048 GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 GS+PLH AA G A LL+ GAN A+NA + PL +A Sbjct: 744 GSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLA 784
>Q9Z2X2:PSD10_MOUSE 26S proteasome non-ATPase regulatory subunit 10 - Mus musculus| (Mouse) Length = 231 Score = 71.6 bits (174), Expect = 1e-11 Identities = 67/253 (26%), Positives = 112/253 (44%) Frame = +1 Query: 412 GCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 GC S + + A G L E + + + LA + R + LH+A + GH EIV LL Sbjct: 3 GC-VSNIMICNLAYSGKLDELKERILADKSLATRTDQDSRTA-LHWACSAGHTEIVEFLL 60 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 + GV +N ++ G + L A G E+V+ L++ A+++ + NG T +H+AA Sbjct: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQ-NGCTPLHYAA----- 114 Query: 772 RCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALN 951 ++ +H + + + + D K T +H AA Sbjct: 115 ------------------SKNRHEIAVMLLEGGANPDA-------KDHYDATAMHRAAAK 149 Query: 952 GHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLA 1131 G+++ V +LL AS + I+D G+TPLH A + L+ +GA++ Sbjct: 150 GNLKMVHILLFYKASTN---IQD-------TEGNTPLHLACDEERVEEAKFLVTQGASIY 199 Query: 1132 AKNASGSTPLMVA 1170 +N TPL VA Sbjct: 200 IENKEEKTPLQVA 212 Score = 54.3 bits (129), Expect = 2e-06 Identities = 35/94 (37%), Positives = 48/94 (51%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 T LH A GH E V+ LL LG V+ D +G +PLH AA G + Sbjct: 42 TALHWACSAGHTEIVEFLLQLGVPVN----------DKDDAGWSPLHIAASAGRDEIVKA 91 Query: 1105 LIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 L+ +GA++ A N +G TPL A S +R+ I +L Sbjct: 92 LLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVML 125
>Q2QLB3:CTTB2_CALMO Cortactin-binding protein 2 - Callicebus moloch (Dusky titi monkey)| Length = 1663 Score = 71.6 bits (174), Expect = 1e-11 Identities = 61/216 (28%), Positives = 90/216 (41%), Gaps = 1/216 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN +C+ GH Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINY-----------SCEDGH------------ 745 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 +A++ AA +GH C+RL+L+ + +V+ AD Sbjct: 746 -----------SALYSAAKNGHTDCVRLLLS----------------AEAQVNAAD---- 774 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 G TPL AA GH ECV+LL+ A+++ G G TPL Sbjct: 775 ----------TNGFTPLCAAAAQGHFECVELLIAYDANINHAA----------GGGQTPL 814 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 + A GN C +LL+ G + K G TP+ A Sbjct: 815 YLACKNGNKECIKLLLEAGTDRCVKTTDGWTPVHAA 850 Score = 70.5 bits (171), Expect = 3e-11 Identities = 59/202 (29%), Positives = 92/202 (45%), Gaps = 11/202 (5%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ T G +PL AAAQGH E V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADTNGF--TPLCAAAAQGHFECVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN--IHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ G+ E ++ L+ + + TD G T +H A Sbjct: 796 LIAYDANINHAAGGGQTPLYLACKNGNKECIKLLLEAGTDRCVKTTD---GWTPVHAAVD 852 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG---------LVKMVNWKA 912 G+ L+L++ VP+ N ++ + S V D D +++ ++N Sbjct: 853 TGNVDSLKLLMYHRVPAHGNSFSEEESESG--VFDLDGEEESPEGKSKPVVTADLINHAN 910 Query: 913 DGGLTPLHMAALNGHVECVQLL 978 G T H+AA G C+++L Sbjct: 911 REGWTAAHIAAAKGFKNCLEIL 932 Score = 65.5 bits (158), Expect = 9e-10 Identities = 69/255 (27%), Positives = 102/255 (40%), Gaps = 27/255 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLSAEAQVNA 772 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 + G T L A GH+E V+ L+ ++ANI+ G T ++ A +G+ C++L+L Sbjct: 773 ADTNGFTPLCAAAAQGHFECVELLIAYDANINHAAG-GGQTPLYLACKNGNKECIKLLL- 830 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 + G + V K G TP+H A G+V+ ++L Sbjct: 831 ---------------------------EAGTDRCV--KTTDGWTPVHAAVDTGNVDSLKL 861 Query: 976 LL-----DLGASVSEVTIEDG------------------TTIDLLG----SGSTPLHYAA 1074 L+ G S SE E G T DL+ G T H AA Sbjct: 862 LMYHRVPAHGNSFSEEESESGVFDLDGEEESPEGKSKPVVTADLINHANREGWTAAHIAA 921 Query: 1075 CGGNAVCCQLLIARG 1119 G C ++L G Sbjct: 922 AKGFKNCLEILCRHG 936
>Q86SG2:ANR23_HUMAN Ankyrin repeat domain-containing protein 23 - Homo sapiens (Human)| Length = 305 Score = 71.6 bits (174), Expect = 1e-11 Identities = 59/218 (27%), Positives = 91/218 (41%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AAA+ ++ L G + N + +TAL AC GH ++V L++ A + D L+ Sbjct: 118 AAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLD 177 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 T + +A GH L+ LNQ VN + Sbjct: 178 R-TPVFWACRGGHLVILK-----------QLLNQGAR-------------------VNAR 206 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA 1089 G TPLH+A H +C++ L++ GA ++ E G T LH A G+ Sbjct: 207 DKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKE----------GDTALHEAVRHGSY 256 Query: 1090 VCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEI 1203 +LL+ GA L +NA+ TP+ +A W R E + Sbjct: 257 KAMKLLLLYGAELGVRNAASVTPVQLARDWQRGIREAL 294 Score = 51.2 bits (121), Expect = 2e-05 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 8/99 (8%) Frame = +1 Query: 508 RYSTFGG--------RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYG 663 +Y T GG + LH+A +GH ++V+ LL +G ++ R+ +T + AC+ G Sbjct: 129 KYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGG 188 Query: 664 HWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCL 780 H +++ L+ A ++ D + G T +H A H CL Sbjct: 189 HLVILKQLLNQGARVNARDKI-GSTPLHVAVRTRHPDCL 226 Score = 47.8 bits (112), Expect = 2e-04 Identities = 26/88 (29%), Positives = 46/88 (52%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A R G L + LL R+ G ++PLH A H + + L+E G +N ++ Sbjct: 184 ACRGGHLVILKQLLNQGARVNARDKIG--STPLHVAVRTRHPDCLEHLIECGAHLNAQDK 241 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANI 708 G TAL +A ++G ++ ++ L+L+ A + Sbjct: 242 EGDTALHEAVRHGSYKAMKLLLLYGAEL 269
>Q7Z020:TRPA1_DROME Transient receptor potential cation channel subfamily A member 1 -| Drosophila melanogaster (Fruit fly) Length = 1197 Score = 71.2 bits (173), Expect = 2e-11 Identities = 72/294 (24%), Positives = 121/294 (41%), Gaps = 41/294 (13%) Frame = +1 Query: 445 AARDGDLQEARALLEYNP---RLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 A G + + + E P RL T + +PLH A+ H +IVS L+ G +IN Sbjct: 306 ACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINA 365 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 + ++ L+ A W+ V L+ A I D +HF ++G L Sbjct: 366 LDKEHRSPLLLAASRSGWKTVHLLIRLGACISVKDAA-ARNVLHFVIMNGGR------LT 418 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 D+ + N Q + L ++N K G +PLH A+ +GH+ ++ Sbjct: 419 DFAEQVANCQTQAQ----------------LKLLLNEKDSMGCSPLHYASRDGHIRSLEN 462 Query: 976 LLDLGASVSE------------------------VTIEDGTTI--DLLGSGSTPLHYAAC 1077 L+ LGA ++ + E G+ I + G+G TPLH ++ Sbjct: 463 LIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQ 522 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVA------------HSWHRNSIEEI 1203 G+ QLL+ RGA L ++ +G PL +A HS H + ++++ Sbjct: 523 QGHTRVVQLLLNRGA-LLHRDHTGRNPLQLAAMSGYTETIELLHSVHSHLLDQV 575 Score = 52.8 bits (125), Expect = 6e-06 Identities = 49/219 (22%), Positives = 86/219 (39%), Gaps = 6/219 (2%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 N+PLH A ++ + LL V+ + N + Q + A + V++L + + Sbjct: 124 NTPLHIAVESDAYDALDYLLSIPVDTGVLNEKKQAPVHLATELNK---VKSLRVMGQYRN 180 Query: 712 RTDYLNGG----TAIHFAALHGHARCLRLVLADY--VPSIPNFLNQTKHRSSEEVSDADF 873 D GG TA+H AA++ H C R+++ ++ P P Sbjct: 181 VIDIQQGGEHGRTALHLAAIYDHEECARILITEFDACPRKP------------------- 221 Query: 874 DDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS 1053 + G P+H AA N + +++ G E + D G+ Sbjct: 222 ------------CNNGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYD--SEGN 267 Query: 1054 TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 PLH A GG+ +L + GA ++ + STP+ +A Sbjct: 268 VPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLA 306 Score = 49.7 bits (117), Expect = 5e-05 Identities = 66/270 (24%), Positives = 106/270 (39%), Gaps = 37/270 (13%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 N PLH A G + V L L+SG +I+ + + T + AC G ++V+ + Sbjct: 267 NVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEK 326 Query: 712 R-----TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFD 876 R TD + T +H A++ H + ++A+ N L++ +HRS Sbjct: 327 RLCLSCTD-VQKMTPLHCASMFDHPDIVSYLVAEGADI--NALDK-EHRS---------- 372 Query: 877 DDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSE-----------VTIEDG 1023 PL +AA + V LL+ LGA +S V + G Sbjct: 373 -----------------PLLLAASRSGWKTVHLLIRLGACISVKDAAARNVLHFVIMNGG 415 Query: 1024 TTIDLL--------------------GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNA 1143 D G +PLHYA+ G+ + LI GA + KN Sbjct: 416 RLTDFAEQVANCQTQAQLKLLLNEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNN 475 Query: 1144 SGSTPLMVAHSWHR-NSIEEILSNEPGGQI 1230 + +PL A + R N++ ++L +E G I Sbjct: 476 NNESPLHFAARYGRYNTVRQLLDSEKGSFI 505
>Q9BXW6:OSBL1_HUMAN Oxysterol-binding protein-related protein 1 - Homo sapiens (Human)| Length = 950 Score = 71.2 bits (173), Expect = 2e-11 Identities = 65/222 (29%), Positives = 98/222 (44%), Gaps = 19/222 (8%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPR---LARYSTFGGRNS-----PLHYAAAQGHHEIVSL 585 ++L+ AR+G+ +E R LLE R +A + G S PLH A GH ++V Sbjct: 7 QQLLHHARNGNAEEVRQLLETMARNEVIADINCKGRSKSNLGWTPLHLACYFGHRQVVQD 66 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHG 765 LL++G E+N+ N G T L +A G E+V L+ +NA+ T +NG H Sbjct: 67 LLKAGAEVNVLNDMGDTPLHRAAFTGRKELVMLLLEYNAD---TTIVNGSGQTAKEVTH- 122 Query: 766 HARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM-----------VNWKA 912 A+ + S+ + +T+ R EE+ A + ++ VN Sbjct: 123 ---------AEEIRSMLEAVERTQQRKLEELLLAAAREGKTTELTALLNRPNPPDVNCSD 173 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 G TPLH AA H +C LL GA + D +DL Sbjct: 174 QLGNTPLHCAAYRAHKQCALKLLRSGADPNLKNKNDQKPLDL 215 Score = 50.1 bits (118), Expect = 4e-05 Identities = 35/98 (35%), Positives = 45/98 (45%) Frame = +1 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 K++ G TPLH+A GH + VQ LL GA V+ + G TPLH AA G Sbjct: 44 KSNLGWTPLHLACYFGHRQVVQDLLKAGAEVNVLN----------DMGDTPLHRAAFTGR 93 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEE 1200 LL+ A+ N SG T V H+ S+ E Sbjct: 94 KELVMLLLEYNADTTIVNGSGQTAKEVTHAEEIRSMLE 131
>Q6GQX6:ANKS6_MOUSE Ankyrin repeat and SAM domain-containing protein 6 - Mus musculus| (Mouse) Length = 883 Score = 71.2 bits (173), Expect = 2e-11 Identities = 77/264 (29%), Positives = 109/264 (41%), Gaps = 26/264 (9%) Frame = +1 Query: 412 GCSASG-ERLVSAARDGDLQEARALLE---------------YNPRLARYSTFGGR---- 531 G A G + L+ A GD AR LLE P R + G Sbjct: 4 GALAPGLQLLLRACEQGDTDTARRLLEPGADPVAGPEAGAEPAGPEAVRAAEAGAPVPVD 63 Query: 532 ------NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML 693 NS L AAA GH +V LL G +N RN+ G +ALMQA + GH V L+ Sbjct: 64 CSDEAGNSALQLAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARCGHVSVAHLLLD 123 Query: 694 FNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADF 873 A+++ + L G + + A+ GH ++L+L +I + H S E Sbjct: 124 HGADVNAQNRL-GASVLTVASRGGHLGVVKLLLE--AGAIVD-----HHTPSGESPATGG 175 Query: 874 DDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS 1053 D L+ G+T L A +GH V+LL++ GA + T+ G Sbjct: 176 SGDELL---------GITALMAAVQHGHEAVVRLLMEWGADPNHT----ARTV-----GW 217 Query: 1054 TPLHYAACGGNAVCCQLLIARGAN 1125 +PL AA G Q L+ +GAN Sbjct: 218 SPLMLAALLGKLNVAQQLVEKGAN 241 Score = 67.0 bits (162), Expect = 3e-10 Identities = 80/306 (26%), Positives = 126/306 (41%), Gaps = 55/306 (17%) Frame = +1 Query: 403 NSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVS 582 N +G SA L+ AAR G + A LL++ + + G S L A+ GH +V Sbjct: 99 NHYGWSA----LMQAARCGHVSVAHLLLDHGADVNAQNRLGA--SVLTVASRGGHLGVVK 152 Query: 583 LLLESGVEINLRNYRGQ--------------TALMQACQYGHWEVVQTLMLFNANIHRTD 720 LLLE+G ++ G+ TALM A Q+GH VV+ LM + A+ + T Sbjct: 153 LLLEAGAIVDHHTPSGESPATGGSGDELLGITALMAAVQHGHEAVVRLLMEWGADPNHTA 212 Query: 721 YLNGGTAIHFAALHGHARCLRLV----------------------------LADYVPSI- 813 G + + AAL G + + LA+Y+ + Sbjct: 213 RTVGWSPLMLAALLGKLNVAQQLVEKGANPDHLSVLEKTAFEVALDRKYRDLAEYLDPLT 272 Query: 814 ------------PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGH 957 P+ K + + V + +D V +VN G TPL +AA+ GH Sbjct: 273 TVRPKTDEEKRRPDIFYALKMGNFQLVKEIADEDPNHVNLVN---GDGATPLMLAAVTGH 329 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 + VQLL++ A + + +D G T L A GN + L+ +GA++A + Sbjct: 330 LPLVQLLVEKHADMDK---QDSV------HGWTALMQATYHGNKEIVKYLLNQGADVALR 380 Query: 1138 NASGST 1155 +G T Sbjct: 381 AKNGYT 386
>Q8BZ25:ANKK1_MOUSE Ankyrin repeat and protein kinase domain-containing protein 1 - Mus| musculus (Mouse) Length = 745 Score = 71.2 bits (173), Expect = 2e-11 Identities = 71/255 (27%), Positives = 113/255 (44%), Gaps = 32/255 (12%) Frame = +1 Query: 502 LARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQ 681 L + R +PLH+ A G E V LLL V+++ + G T L+ A Q ++ Sbjct: 361 LVASDVYENRVTPLHFLVAGGSLEQVRLLLSHDVDVDCQTASGYTPLLIATQDQQPDLCA 420 Query: 682 TLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVS 861 L+ A+ + D +G +HFAA +G RL+L +N +H + Sbjct: 421 LLLAHGADTNLADE-DGWAPLHFAAQNGDDHTARLLLDHGA-----LVNAREHEGWTPLH 474 Query: 862 DA---DFDDDGLVKMVNWKAD------GGLTPLHMAALNGHVECVQLLLDLGASVS---- 1002 A +F++ + +V+ +AD G TPLH+AA GH+ V+LL GA + Sbjct: 475 LAAQNNFENVARL-LVSRQADLSPHEAEGKTPLHVAAYFGHIGLVKLLSGQGAELDAQQR 533 Query: 1003 ------------------EVTIEDGTTIDLLG-SGSTPLHYAACGGNAVCCQLLIARGAN 1125 + ++ G D L SG +PLH AA G + ++L+ GA+ Sbjct: 534 NLRTPLHLAVERGKVRAIQHLLKCGALPDALDHSGYSPLHIAAARGKDLIFKMLLRYGAS 593 Query: 1126 LAAKNASGSTPLMVA 1170 L + G TPL +A Sbjct: 594 LELRTQQGWTPLHLA 608 Score = 64.3 bits (155), Expect = 2e-09 Identities = 57/212 (26%), Positives = 81/212 (38%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AAA+G I +LL G + LR +G T L A GH E++ L + ++ Sbjct: 570 SPLHIAAARGKDLIFKMLLRYGASLELRTQQGWTPLHLATYKGHLEIIHQLAKSHVDLDA 629 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + T +H AA G + +L + PN Q+ Sbjct: 630 LGSMQ-WTPLHLAAFQGEEGVMLALL--QCGANPNAAEQS-------------------- 666 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 G TPLH+A G + LL+ GA + G TP H AA Sbjct: 667 --------GWTPLHLAVHKGTFLGITHLLEYGADIHACN----------KVGWTPAHLAA 708 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 GN ++L+ A + K TPL +A Sbjct: 709 LKGNTAILKVLVKAAAQVDVKGGVSCTPLQLA 740 Score = 54.3 bits (129), Expect = 2e-06 Identities = 43/119 (36%), Positives = 56/119 (47%), Gaps = 3/119 (2%) Frame = +1 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACG 1080 N + G PLH AA NG +LLLD GA V+ E G TPLH AA Sbjct: 430 NLADEDGWAPLHFAAQNGDDHTARLLLDHGALVNAREHE----------GWTPLHLAAQN 479 Query: 1081 GNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSN---EPGGQIRTLPSP 1248 +LL++R A+L+ A G TPL VA + + ++LS E Q R L +P Sbjct: 480 NFENVARLLVSRQADLSPHEAEGKTPLHVAAYFGHIGLVKLLSGQGAELDAQQRNLRTP 538
>O75832:PSD10_HUMAN 26S proteasome non-ATPase regulatory subunit 10 - Homo sapiens| (Human) Length = 226 Score = 70.9 bits (172), Expect = 2e-11 Identities = 67/253 (26%), Positives = 113/253 (44%) Frame = +1 Query: 412 GCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 GC S + + A G L+E + + + LA + R + LH+A + GH EIV LL Sbjct: 3 GC-VSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTA-LHWACSAGHTEIVEFLL 60 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 + GV +N ++ G + L A G E+V+ L+ A ++ + NG T +H+AA Sbjct: 61 QLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQ-NGCTPLHYAA----- 114 Query: 772 RCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALN 951 ++ +H + + + + D K T +H AA Sbjct: 115 ------------------SKNRHEIAVMLLEGGANPDA-------KDHYEATAMHRAAAK 149 Query: 952 GHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLA 1131 G+++ + +LL AS + I+D G+TPLH A +LL+++GA++ Sbjct: 150 GNLKMIHILLYYKASTN---IQD-------TEGNTPLHLACDEERVEEAKLLVSQGASIY 199 Query: 1132 AKNASGSTPLMVA 1170 +N TPL VA Sbjct: 200 IENKEEKTPLQVA 212 Score = 53.9 bits (128), Expect = 3e-06 Identities = 35/94 (37%), Positives = 47/94 (50%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 T LH A GH E V+ LL LG V+ D +G +PLH AA G + Sbjct: 42 TALHWACSAGHTEIVEFLLQLGVPVN----------DKDDAGWSPLHIAASAGRDEIVKA 91 Query: 1105 LIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 L+ +GA + A N +G TPL A S +R+ I +L Sbjct: 92 LLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
>A1X157:CTTB2_ECHTE Cortactin-binding protein 2 - Echinops telfairi (Lesser hedgehog| tenrec) Length = 1666 Score = 70.9 bits (172), Expect = 2e-11 Identities = 61/216 (28%), Positives = 92/216 (42%), Gaps = 1/216 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN +C+ GH Sbjct: 712 GRPTLLQQAAAQGNVTLLSMLLNEEGLDIN-----------HSCEDGH------------ 748 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 +A++ AA +GH C+RL+L + +V+ AD D Sbjct: 749 -----------SALYSAAKNGHTDCVRLLL----------------NAEAQVNAADND-- 779 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 G TP+ AA GHV+CV+LL+ A+++ E G TPL Sbjct: 780 ------------GFTPVCAAAAQGHVKCVELLVAYHANINHAAAE----------GQTPL 817 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 + A GN C +LL+ G + + K G TP+ A Sbjct: 818 YLACKNGNKECIKLLLEAGTDRSVKTRDGWTPVHAA 853 Score = 54.3 bits (129), Expect = 2e-06 Identities = 64/255 (25%), Positives = 98/255 (38%), Gaps = 27/255 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL +S G +S L+ AA GH + V LLL + ++N Sbjct: 717 LQQAAAQGNVTLLSMLLNEEGLDINHSCEDG-HSALYSAAKNGHTDCVRLLLNAEAQVNA 775 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 + G T + A GH + V+ L+ ++ANI+ G T ++ A +G+ C++L+L Sbjct: 776 ADNDGFTPVCAAAAQGHVKCVELLVAYHANINHA-AAEGQTPLYLACKNGNKECIKLLL- 833 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 + G + V K G TP+H A G V+ ++L Sbjct: 834 ---------------------------EAGTDRSV--KTRDGWTPVHAAVDTGSVDGLKL 864 Query: 976 L-----------------------LDLGASVSEVTIEDGTTIDLLG----SGSTPLHYAA 1074 L LD G + E T DL+ G T H AA Sbjct: 865 LLYHRAPACGDGLDTEASRLGVFDLDEGEANPESTPTPVIPADLINHANREGWTAAHIAA 924 Query: 1075 CGGNAVCCQLLIARG 1119 G C ++L G Sbjct: 925 SKGFKNCLKILCRHG 939
>Q812A3:ANR23_MOUSE Ankyrin repeat domain-containing protein 23 - Mus musculus (Mouse)| Length = 306 Score = 70.9 bits (172), Expect = 2e-11 Identities = 58/212 (27%), Positives = 89/212 (41%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AAA+ ++ L G + N + +TAL AC GH ++V L+ A I D L+ Sbjct: 119 AAAENQEALIDKYLADGGDPNAHDKLHRTALHWACLKGHRQLVNKLLAAGAAIEVRDLLD 178 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 T + +A GH L+ LNQ ++++ W Sbjct: 179 R-TPVFWACRGGHLDILK-----------RLLNQGAQVNAQDKI--------------WS 212 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA 1089 TPLH+A GH +C++ L++ GA ++ E G T LH A G+ Sbjct: 213 -----TPLHVAVRMGHSDCLEHLIECGAHINAQDKE----------GDTALHEAVRYGHH 257 Query: 1090 VCCQLLIARGANLAAKNASGSTPLMVAHSWHR 1185 +LL+ GA L KN + TP+ +A W R Sbjct: 258 KATKLLLLYGAKLGVKNVASQTPVQLARDWQR 289 Score = 57.8 bits (138), Expect = 2e-07 Identities = 42/166 (25%), Positives = 72/166 (43%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH+A +GH ++V+ LL +G I +R+ +T + AC+ GH ++++ L+ A ++ D Sbjct: 149 LHWACLKGHRQLVNKLLAAGAAIEVRDLLDRTPVFWACRGGHLDILKRLLNQGAQVNAQD 208 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 + T +H A GH+ CL + + H + Sbjct: 209 KI-WSTPLHVAVRMGHSDCLE-----------HLIECGAH-------------------I 237 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 N + G T LH A GH + +LLL GA + + T + L Sbjct: 238 NAQDKEGDTALHEAVRYGHHKATKLLLLYGAKLGVKNVASQTPVQL 283 Score = 52.4 bits (124), Expect = 8e-06 Identities = 28/88 (31%), Positives = 45/88 (51%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A R G L + LL ++ ++PLH A GH + + L+E G IN ++ Sbjct: 185 ACRGGHLDILKRLLNQGAQVNAQDKIW--STPLHVAVRMGHSDCLEHLIECGAHINAQDK 242 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANI 708 G TAL +A +YGH + + L+L+ A + Sbjct: 243 EGDTALHEAVRYGHHKATKLLLLYGAKL 270 Score = 48.9 bits (115), Expect = 8e-05 Identities = 27/86 (31%), Positives = 48/86 (55%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +P+ +A GH +I+ LL G ++N ++ T L A + GH + ++ L+ A+I+ Sbjct: 180 TPVFWACRGGHLDILKRLLNQGAQVNAQDKIWSTPLHVAVRMGHSDCLEHLIECGAHINA 239 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVL 792 D G TA+H A +GH + +L+L Sbjct: 240 QD-KEGDTALHEAVRYGHHKATKLLL 264
>Q9GKW8:AND1A_MACFA Ankyrin repeat and death domain-containing protein 1A precursor -| Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) Length = 418 Score = 70.9 bits (172), Expect = 2e-11 Identities = 66/229 (28%), Positives = 103/229 (44%), Gaps = 8/229 (3%) Frame = +1 Query: 544 HYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDY 723 H AA G + + L+ SG + ++++ G TAL A GH V+Q L+ ++ + Sbjct: 73 HRAAEHGQLDALDFLVGSGCDHSVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQN- 131 Query: 724 LNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQ--------TKHRSSEEVSDADFDD 879 G TA+H AA H C+RL+L S N L Q SE+VS Sbjct: 132 AEGLTALHAAAGGTHPHCVRLLLR--AGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHA 189 Query: 880 DGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTP 1059 G + AD G +PLH+A ++ VQLL++ S S++ D TP Sbjct: 190 GGCTNV----ADHGASPLHLAVMHNFPALVQLLIN---SDSDLNAMDNRQ-------QTP 235 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 LH AA ++L+ G +L ++ G T L VA + S+ +++ Sbjct: 236 LHLAAEHAWQDIAEMLLIAGVDLNLRDKQGKTALAVAARSNHVSLVDMI 284 Score = 60.8 bits (146), Expect = 2e-08 Identities = 56/193 (29%), Positives = 81/193 (41%), Gaps = 2/193 (1%) Frame = +1 Query: 562 GHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLM--LFNANIHRTDYLNGG 735 GH I+ +L+ SG +I+ ++ G T L A Q GH V+ +M L + + D L G Sbjct: 11 GHLRILQILVNSGAKIHCKSKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKL-GR 69 Query: 736 TAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKAD 915 TA H AA HG L ++ V D + Sbjct: 70 TAFHRAAEHGQLDALDFLVGS--------------GCDHSVKDKE--------------- 100 Query: 916 GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVC 1095 G T LH+AA GH+ +Q L+D+G + E E G T LH AA G + C Sbjct: 101 -GNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAE----------GLTALHAAAGGTHPHC 149 Query: 1096 CQLLIARGANLAA 1134 +LL+ G+ + A Sbjct: 150 VRLLLRAGSTVNA 162 Score = 43.1 bits (100), Expect = 0.005 Identities = 20/54 (37%), Positives = 34/54 (62%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLM 690 + +PLH AA +I +LL +GV++NLR+ +G+TAL A + H +V ++ Sbjct: 232 QQTPLHLAAEHAWQDIAEMLLIAGVDLNLRDKQGKTALAVAARSNHVSLVDMII 285
>Q09YK4:CTTB2_ATEGE Cortactin-binding protein 2 - Ateles geoffroyi (Black-handed spider| monkey) Length = 1660 Score = 70.5 bits (171), Expect = 3e-11 Identities = 61/211 (28%), Positives = 96/211 (45%), Gaps = 11/211 (5%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGF--TPLCAAAAQGHFECVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN--IHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ G+ E ++ L+ A+ + TD G T++H A Sbjct: 796 LVAYDAHINHAADGGQTPLYLACKNGNKECIKLLLEAGADRSVKTTD---GWTSVHAAVD 852 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG---------LVKMVNWKA 912 G+ L+L++ VP+ N ++ + S V D D +++ ++N Sbjct: 853 TGNVDSLKLLMYHRVPAHGNSFSEEESESG--VFDLDGEEESPEGKSKPVVTADLINHAN 910 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSE 1005 G T H+AA G C+++L G +E Sbjct: 911 REGWTAAHIAASKGFKNCLEILCRHGGLETE 941 Score = 67.4 bits (163), Expect = 2e-10 Identities = 62/216 (28%), Positives = 91/216 (42%), Gaps = 1/216 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN +C+ GH Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINY-----------SCEDGH------------ 745 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 +A++ AA +GH C+RL+L+ + +V+ AD Sbjct: 746 -----------SALYSAAKNGHTDCVRLLLS----------------AEAQVNAAD---- 774 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 G TPL AA GH ECV+LL+ A ++ DG G TPL Sbjct: 775 ----------KNGFTPLCAAAAQGHFECVELLVAYDAHINHAA--DG--------GQTPL 814 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 + A GN C +LL+ GA+ + K G T + A Sbjct: 815 YLACKNGNKECIKLLLEAGADRSVKTTDGWTSVHAA 850 Score = 61.6 bits (148), Expect = 1e-08 Identities = 69/256 (26%), Positives = 102/256 (39%), Gaps = 28/256 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLSAEAQVNA 772 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH+E V+ L+ ++A+I H D G T ++ A +G+ C++L+L Sbjct: 773 ADKNGFTPLCAAAAQGHFECVELLVAYDAHINHAAD--GGQTPLYLACKNGNKECIKLLL 830 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G T +H A G+V+ ++ Sbjct: 831 ----------------------------EAGADRSV--KTTDGWTSVHAAVDTGNVDSLK 860 Query: 973 LLL-----DLGASVSEVTIEDG------------------TTIDLLG----SGSTPLHYA 1071 LL+ G S SE E G T DL+ G T H A Sbjct: 861 LLMYHRVPAHGNSFSEEESESGVFDLDGEEESPEGKSKPVVTADLINHANREGWTAAHIA 920 Query: 1072 ACGGNAVCCQLLIARG 1119 A G C ++L G Sbjct: 921 ASKGFKNCLEILCRHG 936
>Q96DX5:ASB9_HUMAN Ankyrin repeat and SOCS box protein 9 - Homo sapiens (Human)| Length = 294 Score = 70.5 bits (171), Expect = 3e-11 Identities = 59/209 (28%), Positives = 87/209 (41%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH A GH V +LL+ G ++N T L AC G W+ V L+ A++ Sbjct: 71 SPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQP 130 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 L + IH AA GH C+ ++A Y +I + ++ Sbjct: 131 ESDL--ASPIHEAARRGHVECVNSLIA-YGGNIDHKISHLG------------------- 168 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 TPL++A N CV+ LL+ GA V++ +D +PLH A Sbjct: 169 ----------TPLYLACENQQRACVKKLLESGADVNQGKGQD-----------SPLHAVA 207 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL 1161 + LL+ GA+ AKNA G P+ Sbjct: 208 RTASEELACLLMDFGADTQAKNAEGKRPV 236 Score = 52.8 bits (125), Expect = 6e-06 Identities = 48/188 (25%), Positives = 78/188 (41%), Gaps = 23/188 (12%) Frame = +1 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM 897 D ++ + +H AA+HGH LR N ++Q Sbjct: 32 DAVSDWSPMHEAAIHGHQLSLR-----------NLISQGW-------------------A 61 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVT---------------------- 1011 VN ++PLH A L GH+ CV++LL GA V+ VT Sbjct: 62 VNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLL 121 Query: 1012 IEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA-HSWHRN 1188 ++ G ++ ++P+H AA G+ C LIA G N+ K + TPL +A + R Sbjct: 122 LQHGASVQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRA 181 Query: 1189 SIEEILSN 1212 ++++L + Sbjct: 182 CVKKLLES 189 Score = 41.2 bits (95), Expect = 0.018 Identities = 40/171 (23%), Positives = 69/171 (40%), Gaps = 1/171 (0%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI- 708 ++PL A G + V+LLL+ G + + + + +A + GH E V +L+ + NI Sbjct: 103 HTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SPIHEAARRGHVECVNSLIAYGGNID 161 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 H+ +L GT ++ A + C++ +L S AD + Sbjct: 162 HKISHL--GTPLYLACENQQRACVKKLLE---------------------SGADVN---- 194 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 + G +PLH A E LL+D GA E ++L+ Sbjct: 195 ------QGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELV 239
>Q9NU02:ANKR5_HUMAN Ankyrin repeat domain-containing protein 5 - Homo sapiens (Human)| Length = 776 Score = 70.5 bits (171), Expect = 3e-11 Identities = 77/280 (27%), Positives = 120/280 (42%), Gaps = 34/280 (12%) Frame = +1 Query: 433 RLVSAARDGDLQEARALLEYN-PRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 +++ R+ D ++ L + P L Y+ S LH A+ ++VS LL+ G Sbjct: 15 KVLQCVRNKDKKQIEKLTKLGYPELINYTEPINGLSALHLASVSNDIDMVSFLLDLGAHP 74 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAAL---HGHARCL 780 ++++ G T M+A + GH ++ L A++ D N G + F + H RC Sbjct: 75 DVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVD--NEGKGVLFYCILPTKRHYRCA 132 Query: 781 RLVLADYVPSIPNFLNQTKH---RSSEEVSDA-DFDDDGLVKMVNWKA---DGGLTPLHM 939 L+ ++ + N + K R+ E+ D D L K N A G T L Sbjct: 133 -LIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVCLTFLEKGANPNAINSSTGRTALME 191 Query: 940 AALNGHVECVQLLLDLGASVSEVTIE---------DGTTIDLLG--------------SG 1050 A+ G VE V+ +L+ G V+ + G D+L +G Sbjct: 192 ASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISING 251 Query: 1051 STPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 +TPLHYAA GG A CC+ + RG +L KN TP VA Sbjct: 252 NTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVA 291 Score = 43.1 bits (100), Expect = 0.005 Identities = 28/79 (35%), Positives = 43/79 (54%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 TPL A +G+++ V+ LL+ GA+V+ T + L TPLH+A G +L Sbjct: 527 TPLMTACASGNIDVVKFLLEKGANVN-------ATDNFLW---TPLHFACHAGQQDIVEL 576 Query: 1105 LIARGANLAAKNASGSTPL 1161 L+ GA + A + + STPL Sbjct: 577 LVESGALIDAASINNSTPL 595 Score = 41.2 bits (95), Expect = 0.018 Identities = 31/118 (26%), Positives = 55/118 (46%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L++A G++ + LLE + F +PLH+A G +IV LL+ESG I+ Sbjct: 529 LMTACASGNIDVVKFLLEKGANVNATDNFLW--TPLHFACHAGQQDIVELLVESGALIDA 586 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 + T L +A + + V+ L+ A + + G +A+ A + R + L+ Sbjct: 587 ASINNSTPLNRAIESCRLDTVKYLLDIGAKF-QLENRKGHSAMDVAKAYADYRIIDLI 643 Score = 38.9 bits (89), Expect = 0.088 Identities = 34/134 (25%), Positives = 60/134 (44%) Frame = +1 Query: 592 ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA 771 ESG+ +++++ +T LM AC G+ +VV+ L+ AN++ TD T +HFA G Sbjct: 513 ESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFL-WTPLHFACHAGQQ 571 Query: 772 RCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALN 951 + L++ S + A ++ TPL+ A + Sbjct: 572 DIVELLV----------------ESGALIDAASINNS--------------TPLNRAIES 601 Query: 952 GHVECVQLLLDLGA 993 ++ V+ LLD+GA Sbjct: 602 CRLDTVKYLLDIGA 615 Score = 38.1 bits (87), Expect = 0.15 Identities = 50/197 (25%), Positives = 77/197 (39%), Gaps = 2/197 (1%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PL A A G+ ++V LLE G +N + T L AC G ++V+ L+ A I Sbjct: 527 TPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDA 586 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSI-PNF-LNQTKHRSSEEVSDADFDDDGL 888 +N T ++ A RL Y+ I F L K S+ +V+ A + D + Sbjct: 587 AS-INNSTPLNRA-----IESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKA-YADYRI 639 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 + ++ K D P L G + L E+ E+ + G +T Sbjct: 640 IDLIKEKLDNLPKPAENQKLKGKTPPI-----LKTEGPEIKKEEELLSSIYGVPTTSEGK 694 Query: 1069 AACGGNAVCCQLLIARG 1119 GN V LI G Sbjct: 695 KVQKGNVVHLNSLITSG 711
>Q9C7A2:Y3236_ARATH Ankyrin repeat-containing protein At3g12360 - Arabidopsis thaliana| (Mouse-ear cress) Length = 590 Score = 70.1 bits (170), Expect = 4e-11 Identities = 61/212 (28%), Positives = 94/212 (44%), Gaps = 11/212 (5%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L +AA G L + LL+Y+ R + PLH AA QGHH IV +LL+ ++ Sbjct: 133 LFTAADKGHLDVVKELLKYSSRESIAKKNRSGYDPLHIAAIQGHHAIVEVLLDHDATLSQ 192 Query: 616 R-NYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 T L+ A GH EVV L+ N+ N A+H AA GH ++ +L Sbjct: 193 TFGPSNATPLVSAAMRGHTEVVNQLLSKAGNLLEISRSNNKNALHLAARQGHVEVIKALL 252 Query: 793 ADYVPSIPNFLNQ---------TKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAA 945 + P + +++ K +SSE V D +V + + T LH+A Sbjct: 253 SK-DPQLARRIDKKGQTALHMAVKGQSSEVVKLLLDADPAIVMQPDKSCN---TALHVAT 308 Query: 946 LNGHVECVQLLLDL-GASVSEVTIEDGTTIDL 1038 E V+LLL L + + +T + T +D+ Sbjct: 309 RKKRAEIVELLLSLPDTNANTLTRDHKTALDI 340 Score = 57.0 bits (136), Expect = 3e-07 Identities = 67/247 (27%), Positives = 104/247 (42%), Gaps = 17/247 (6%) Frame = +1 Query: 607 INLRNYRGQTALMQACQYGHWEVVQTLMLFNA--NIHRTDYLNGGTAIHFAALHGHARCL 780 +N N G+TAL A GH +VV+ L+ +++ +I + + +G +H AA+ GH + Sbjct: 122 VNEVNELGETALFTAADKGHLDVVKELLKYSSRESIAKKN-RSGYDPLHIAAIQGHHAIV 180 Query: 781 RLVL-------ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHM 939 ++L + PS L R EV + G ++ LH+ Sbjct: 181 EVLLDHDATLSQTFGPSNATPLVSAAMRGHTEVVNQLLSKAG--NLLEISRSNNKNALHL 238 Query: 940 AALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLI-AR 1116 AA GHVE ++ LL ++ ID G T LH A G ++ +LL+ A Sbjct: 239 AARQGHVEVIKALLSKDPQLAR-------RID--KKGQTALHMAVKGQSSEVVKLLLDAD 289 Query: 1117 GANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPYLC-------LPLMSI 1275 A + + S +T L VA R I E+L + P TL + LPL Sbjct: 290 PAIVMQPDKSCNTALHVATRKKRAEIVELLLSLPDTNANTLTRDHKTALDIAEGLPLSEE 349 Query: 1276 MSIAREC 1296 S +EC Sbjct: 350 SSYIKEC 356
>Q9ERC1:MYO16_RAT Myosin-XVI - Rattus norvegicus (Rat)| Length = 1912 Score = 70.1 bits (170), Expect = 4e-11 Identities = 79/256 (30%), Positives = 116/256 (45%), Gaps = 3/256 (1%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 S LH A + I +L++ GV +N ++ + AC + ++V L+L AN+ Sbjct: 95 SLLHLCARYDNVFIAEVLIDRGVNVNHQDEDFWAPMHIACACDNPDIVLLLILAGANVLL 154 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTK-HRSSEEVSDA-DFDDDGL 888 D +NG + +A + + L D N L Q K R ++D F G Sbjct: 155 QD-VNGNIPLDYAVEGTESSAILLAYLDENGVDLNSLRQIKLQRPLSMLTDVRHFLSSG- 212 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 VN K D G+T LHMA +G+ E V LLL+ G ++ ++DG TPLH Sbjct: 213 -GDVNEKNDDGVTLLHMACASGYKEVVLLLLEHGGDLN--GMDDGYW--------TPLHL 261 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEE-ILSNEPGGQIRTLPS 1245 AA G +LL+A AN N +G P +A S SIEE +L E + R S Sbjct: 262 AAKYGQTTLVKLLLAHQANPHLVNCNGEKPSDIAAS---ESIEEMLLKAEIAWEERMKES 318 Query: 1246 PYLCLPLMSIMSIARE 1293 P S+ S+A+E Sbjct: 319 P-------SVPSLAQE 327
>Q02989:LITA_LATMA Alpha-latroinsectotoxin precursor - Latrodectus mactans (Black widow| spider) Length = 1411 Score = 70.1 bits (170), Expect = 4e-11 Identities = 64/260 (24%), Positives = 114/260 (43%), Gaps = 32/260 (12%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH + + L+ + IN+++ G T L A + V + L A ++ Sbjct: 604 TPLHLSISSTSETAAILIRNTNAVINIKSKVGLTPLHLATLQNNLSVSKLLAGKGAYLND 663 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHR--------SSEEVSDAD 870 D NG T +H+AA+ G+ + +L +I + K +V++ Sbjct: 664 GD-ANGMTPLHYAAMTGNLEMVDFLLNQQYININAATKEKKWTPLHLAILFKKNDVAERL 722 Query: 871 FDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVT------------- 1011 D+ L + + +GG+ PLH+A+ G+ + V LL A V+ +T Sbjct: 723 LSDENL--NIRLETNGGINPLHLASATGNKQLVIELLAKNADVTRLTSKGFSALHLGIIG 780 Query: 1012 ---------IEDGTTI-DLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL 1161 +E G + D SG TPLH+AA G A +LL++RGA++ A++ + P+ Sbjct: 781 KNEEIPFFLVEKGANVNDKTNSGVTPLHFAAGLGKANIFRLLLSRGADIKAEDINSQMPI 840 Query: 1162 MVAHS-WHRNSIEEILSNEP 1218 A S H + ++ +P Sbjct: 841 HEAVSNGHLEIVRILIEKDP 860 Score = 54.3 bits (129), Expect = 2e-06 Identities = 61/241 (25%), Positives = 94/241 (39%), Gaps = 25/241 (10%) Frame = +1 Query: 508 RYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTL 687 R T GG N PLH A+A G+ ++V LL ++ +G +AL + E+ L Sbjct: 731 RLETNGGIN-PLHLASATGNKQLVIELLAKNADVTRLTSKGFSALHLGIIGKNEEIPFFL 789 Query: 688 MLFNANIHRTDYLNGG-TAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSD 864 + AN++ D N G T +HFAA G A RL+L+ Sbjct: 790 VEKGANVN--DKTNSGVTPLHFAAGLGKANIFRLLLS---------------------RG 826 Query: 865 ADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEV------------ 1008 AD + + + P+H A NGH+E V++L++ S+ V Sbjct: 827 ADIKAEDINSQM---------PIHEAVSNGHLEIVRILIEKDPSLMNVKNIRNEYPFYLA 877 Query: 1009 ------------TIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGS 1152 +D ++ +G+T LH + G Q L+ GAN KN Sbjct: 878 VEKRYKDIFDYFVSKDANVNEVDHNGNTLLHLFSSTGELEVVQFLMQNGANFRLKNNERK 937 Query: 1153 T 1155 T Sbjct: 938 T 938 Score = 43.9 bits (102), Expect = 0.003 Identities = 40/168 (23%), Positives = 63/168 (37%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH+AA G I LLL G +I + Q + +A GH E+V+ L+ + ++ Sbjct: 805 TPLHFAAGLGKANIFRLLLSRGADIKAEDINSQMPIHEAVSNGHLEIVRILIEKDPSLMN 864 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + + A + + DY S +N+ H Sbjct: 865 VKNIRNEYPFYLAVEKRYKD-----IFDYFVSKDANVNEVDH------------------ 901 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 G T LH+ + G +E VQ L+ GA+ E T DL Sbjct: 902 -------NGNTLLHLFSSTGELEVVQFLMQNGANFRLKNNERKTFFDL 942 Score = 40.8 bits (94), Expect = 0.023 Identities = 49/213 (23%), Positives = 87/213 (40%), Gaps = 3/213 (1%) Frame = +1 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHG 765 L+++G ++ G+ A+ A G+++V + L+ + N+ NG T +H AA Sbjct: 486 LIQNGANVSETFELGRGAIHAAASAGNYDVGELLLNKDINLLEKADKNGYTPLHIAADSN 545 Query: 766 HARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAA 945 + ++ + +AD + V K+D TPLH+AA Sbjct: 546 KNDFVMFLIGN---------------------NADVN-------VRTKSDL-FTPLHLAA 576 Query: 946 LNGHVECVQLLLDLGASVSEVTIEDGTTIDLLG---SGSTPLHYAACGGNAVCCQLLIAR 1116 + Q L+D+ T IDL SG TPLH + + L+ Sbjct: 577 RRDLTDVTQTLIDI------------TEIDLNAQDKSGFTPLHLSISSTSETAAILIRNT 624 Query: 1117 GANLAAKNASGSTPLMVAHSWHRNSIEEILSNE 1215 A + K+ G TPL +A + S+ ++L+ + Sbjct: 625 NAVINIKSKVGLTPLHLATLQNNLSVSKLLAGK 657 Score = 36.6 bits (83), Expect = 0.44 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 1/59 (1%) Frame = +1 Query: 538 PLHYAAAQGHHEIVSLLLE-SGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 PL+ AA QG EIV L+E V+IN RN TAL A + +VV+ L+ A+++ Sbjct: 1116 PLYIAARQGRFEIVRCLIEVHKVDINTRNKERFTALHAAARNDFMDVVKYLVRQGADVN 1174
>Q2QLF8:CTTB2_CALJA Cortactin-binding protein 2 - Callithrix jacchus (Common marmoset)| Length = 1662 Score = 70.1 bits (170), Expect = 4e-11 Identities = 62/216 (28%), Positives = 92/216 (42%), Gaps = 1/216 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN +C+ GH Sbjct: 708 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINY-----------SCEDGH------------ 744 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 +A++ AA +GH C+RL+L+ + +V+ AD Sbjct: 745 -----------SALYSAAKNGHTDCVRLLLS----------------AEAQVNAAD---- 773 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 G TPL AA GH ECV+LL+ A+++ DG G TPL Sbjct: 774 ----------KNGFTPLCAAAAQGHFECVELLIAYDANINHAA--DG--------GQTPL 813 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 + A GN C +LL+ G + + K G TP+ A Sbjct: 814 YLACKNGNKECIRLLLEAGTDRSVKTTDGWTPVHAA 849 Score = 67.8 bits (164), Expect = 2e-10 Identities = 59/209 (28%), Positives = 94/209 (44%), Gaps = 9/209 (4%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH E V L Sbjct: 737 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGF--TPLCAAAAQGHFECVEL 794 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN--IHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ G+ E ++ L+ + + TD G T +H A Sbjct: 795 LIAYDANINHAADGGQTPLYLACKNGNKECIRLLLEAGTDRSVKTTD---GWTPVHAAVD 851 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSE-EVSDADFDDDGLVK------MVNWKADG 918 G+ L+L++ VP+ N ++ + S ++ + + +G K +N Sbjct: 852 TGNVDSLKLLMYHRVPAHGNSFSEEESESGVFDLDEGEESPEGKSKPVVTADFINHANRE 911 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSE 1005 G T H+AA G C+++L G +E Sbjct: 912 GWTAAHIAASKGFKNCLEILCRHGGLETE 940 Score = 66.2 bits (160), Expect = 5e-10 Identities = 71/256 (27%), Positives = 102/256 (39%), Gaps = 28/256 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 713 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLSAEAQVNA 771 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH+E V+ L+ ++ANI H D G T ++ A +G+ C+RL+L Sbjct: 772 ADKNGFTPLCAAAAQGHFECVELLIAYDANINHAAD--GGQTPLYLACKNGNKECIRLLL 829 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G TP+H A G+V+ ++ Sbjct: 830 ----------------------------EAGTDRSV--KTTDGWTPVHAAVDTGNVDSLK 859 Query: 973 LLL-----DLGASVSEVTIEDG------------------TTIDLLG----SGSTPLHYA 1071 LL+ G S SE E G T D + G T H A Sbjct: 860 LLMYHRVPAHGNSFSEEESESGVFDLDEGEESPEGKSKPVVTADFINHANREGWTAAHIA 919 Query: 1072 ACGGNAVCCQLLIARG 1119 A G C ++L G Sbjct: 920 ASKGFKNCLEILCRHG 935
>Q4I8B6:AKR1_GIBZE Palmitoyltransferase AKR1 - Gibberella zeae (Fusarium graminearum)| Length = 702 Score = 70.1 bits (170), Expect = 4e-11 Identities = 75/257 (29%), Positives = 101/257 (39%), Gaps = 7/257 (2%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 ++ AR GD+ L E A Y G +PLH+AA + + L+E G EIN Sbjct: 32 IMQVARVGDVPAMEKLFESGEYDATYHDDEGI-TPLHWAAINNQYAMCKFLIEHGAEINR 90 Query: 616 RNYRG-QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 + T L A Q H+ V L+ A+ TD G +H + +G+ L L+L Sbjct: 91 KGGESIATPLQWAAQRCHYYTVNLLLQHGADPLVTD-AQGYNTLHISTFNGNVLLLVLLL 149 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 +P +V D G T L AA G +CV Sbjct: 150 HQGIP--------------VDVIDT----------------FGHTALMWAAYKGFPQCVD 179 Query: 973 LLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGS 1152 L L GASV T E G T LH+A G+ C LI GA+ AK +G Sbjct: 180 LFLRWGASV-HATDE---------QGFTALHWALVKGSPGCILKLIEYGADRFAKTQTGK 229 Query: 1153 TPLMVAH------SWHR 1185 TP + A +WHR Sbjct: 230 TPSVTAKELNTEVAWHR 246 Score = 50.4 bits (119), Expect = 3e-05 Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 12/134 (8%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH + G+ ++ LLL G+ +++ + G TALM A G + V + + A++H TD Sbjct: 133 LHISTFNGNVLLLVLLLHQGIPVDVIDTFGHTALMWAAYKGFPQCVDLFLRWGASVHATD 192 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADY------------VPSIPNFLNQTKHRSSEEVSD 864 G TA+H+A + G C+ L L +Y PS+ T+ +++ Sbjct: 193 E-QGFTALHWALVKGSPGCI-LKLIEYGADRFAKTQTGKTPSVTAKELNTEVAWHRALTE 250 Query: 865 ADFDDDGLVKMVNW 906 FD+DG + W Sbjct: 251 CGFDEDGHPAVPPW 264
>Q91ZT8:ASB9_MOUSE Ankyrin repeat and SOCS box protein 9 - Mus musculus (Mouse)| Length = 290 Score = 69.7 bits (169), Expect = 5e-11 Identities = 60/209 (28%), Positives = 87/209 (41%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH A +GH S+LL G ++N +T L AC G + V L+ A H Sbjct: 67 SPLHEACLRGHLSCASVLLSHGAQVNGMTIDWRTPLFNACVSGSQDCVNLLLQHGATPHP 126 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 L + IH AA G+ +C+ + A ++ D++ L Sbjct: 127 ETEL--ASPIHEAAKRGYVKCIESLAA-------------------HGANIDYNISHLG- 164 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 TPL++A N V C + LL+ G SV++ G +D +PLH A Sbjct: 165 ----------TPLYVACKNQQVACAKKLLESGVSVNQ-----GKGLD------SPLHVVA 203 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL 1161 + LL+ GAN AKNA G P+ Sbjct: 204 RMSSVELVHLLMDFGANAQAKNADGKRPV 232 Score = 49.7 bits (117), Expect = 5e-05 Identities = 36/105 (34%), Positives = 49/105 (46%), Gaps = 22/105 (20%) Frame = +1 Query: 922 LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTID-------------LLGSGST-- 1056 ++PLH A L GH+ C +LL GA V+ +TI+ T + LL G+T Sbjct: 66 VSPLHEACLRGHLSCASVLLSHGAQVNGMTIDWRTPLFNACVSGSQDCVNLLLQHGATPH 125 Query: 1057 -------PLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 P+H AA G C + L A GAN+ + TPL VA Sbjct: 126 PETELASPIHEAAKRGYVKCIESLAAHGANIDYNISHLGTPLYVA 170
>Q8BLA8:TRPA1_MOUSE Transient receptor potential cation channel subfamily A member 1 -| Mus musculus (Mouse) Length = 1125 Score = 69.3 bits (168), Expect = 6e-11 Identities = 67/259 (25%), Positives = 115/259 (44%), Gaps = 17/259 (6%) Frame = +1 Query: 445 AARDGDLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLE-SGVEINL 615 AA ++ + LL NP L + SPLH A ++E++ +L E INL Sbjct: 106 AAEKNQVESVKFLLSQGANPNLRNRNMM----SPLHIAVHGMYNEVIKVLTEHKATNINL 161 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 G TALM C + E +Q L+ A + +++ G +H AA G +C+ L+LA Sbjct: 162 EGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKW-GDYPVHQAAFSGAKKCMELILA 220 Query: 796 ---DYVPSIPNFLNQTKHRSSE----EVSDADFDDDGLVKM-------VNWKADGGLTPL 933 S +N H+ + V D D ++KM ++ + L Sbjct: 221 YGEKNGYSRETHINFVNHKKASPLHLAVQSGDLD---MIKMCLDNGAHIDMMENAKCMAL 277 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA 1113 H AA G + V+L++ S++ +D G+ T LH A+ + + LI+ Sbjct: 278 HFAATQGATDIVKLMISSYTGSSDIV----NAVD--GNQETLLHRASLFDHHDLAEYLIS 331 Query: 1114 RGANLAAKNASGSTPLMVA 1170 GA++ + ++ G +PL++A Sbjct: 332 VGADINSTDSEGRSPLILA 350 Score = 63.2 bits (152), Expect = 4e-09 Identities = 48/160 (30%), Positives = 83/160 (51%), Gaps = 10/160 (6%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA GH ++V LLL+ G + L ++ G TAL A G+ + ++ ++ + N+ Sbjct: 485 TPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVIL--DTNLKC 541 Query: 715 TDYLN--GGTAIHFAALHGHARCLRLVLADYVPSIPN-----FLNQTKHRSSEEVSDADF 873 TD L+ G TA+HFAA GHA+ + ++L+ + N FL+ H +EV Sbjct: 542 TDRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTI 601 Query: 874 DD---DGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 + D +++ + P+ M + EC+++LLD Sbjct: 602 RNKRWDECLQVFTHNSPSNRCPI-MEMVEYLPECMKVLLD 640 Score = 62.8 bits (151), Expect = 6e-09 Identities = 60/259 (23%), Positives = 111/259 (42%), Gaps = 5/259 (1%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLM--LFNANI 708 +PLHYA QG V+ LL V I+ ++ ++ L A YG Q L+ + + + Sbjct: 416 TPLHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRL 475 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 L+G T +H AA +GH + ++L+L + + +SD + Sbjct: 476 LNEGDLHGMTPLHLAAKNGHDKVVQLLLK---------------KGALFLSDHN------ 514 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 G T LH A++ G+ + ++++LD ++ E+G +T LH+ Sbjct: 515 ----------GWTALHHASMGGYTQTMKVILDTNLKCTDRLDEEG---------NTALHF 555 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGG---QIRTL 1239 AA G+A +L++ A++ S + H+ + + + N+ Q+ T Sbjct: 556 AAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTIRNKRWDECLQVFTH 615 Query: 1240 PSPYLCLPLMSIMSIAREC 1296 SP P+M ++ EC Sbjct: 616 NSPSNRCPIMEMVEYLPEC 634 Score = 51.2 bits (121), Expect = 2e-05 Identities = 34/106 (32%), Positives = 54/106 (50%) Frame = +1 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAV 1092 D L PLH AA G VE ++L+++ G+S + I DG G+TPLH AA Sbjct: 62 DENLCPLHHAAAEGQVELMELIIN-GSSCEVLNIMDGY-------GNTPLHCAAEKNQVE 113 Query: 1093 CCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQI 1230 + L+++GAN +N + +PL +A N + ++L+ I Sbjct: 114 SVKFLLSQGANPNLRNRNMMSPLHIAVHGMYNEVIKVLTEHKATNI 159 Score = 47.8 bits (112), Expect = 2e-04 Identities = 58/243 (23%), Positives = 102/243 (41%), Gaps = 2/243 (0%) Frame = +1 Query: 397 VGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEI 576 VG CS ++ +GD+ ++ +L++Y PLH+AAA+G E+ Sbjct: 25 VGEDMDCSKESFKVDI---EGDMCRLEDFIKNRRKLSKYED--ENLCPLHHAAAEGQVEL 79 Query: 577 VSLLLE-SGVEI-NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHF 750 + L++ S E+ N+ + G T L A + E V+ L+ AN + + N + +H Sbjct: 80 MELIINGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFLLSQGANPNLRN-RNMMSPLHI 138 Query: 751 AALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTP 930 A+HG + VL T+H+++ +N + + G T Sbjct: 139 -AVHGMYNEVIKVL-------------TEHKATN---------------INLEGENGNTA 169 Query: 931 LHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLI 1110 L + E +Q+LL+ GA + + G P+H AA G C +L++ Sbjct: 170 LMSTCAKDNSEALQILLEKGAKLCKSN----------KWGDYPVHQAAFSGAKKCMELIL 219 Query: 1111 ARG 1119 A G Sbjct: 220 AYG 222
>Q18297:TRPA1_CAEEL Transient receptor potential cation channel subfamily A member 1| homolog - Caenorhabditis elegans Length = 1193 Score = 69.3 bits (168), Expect = 6e-11 Identities = 70/267 (26%), Positives = 117/267 (43%), Gaps = 25/267 (9%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE-INLRN 621 AA G L+ +AL+E + + PLH AA E+VS L+E + I++ + Sbjct: 301 AAEKGFLEVLKALVEAGGNKNELNEV--KAVPLHVAAQMNQLEVVSYLIEEEKDNIDVVD 358 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADY 801 +G T LM A + + V+ L+ AN+ TD + T + A + +L D+ Sbjct: 359 EQGLTPLMMAVTHDSKKCVEYLIAKKANLTITDK-DERTPVFIGAKFNALSSVEYIL-DH 416 Query: 802 VPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLL 981 + ++ +S + +D MVN TP+H+ A NG++E +QLL Sbjct: 417 LRKKNKETERSALKSPTRNTLRIVSEDVRRTMVNMVDRDQNTPMHIVASNGYLEMMQLLQ 476 Query: 982 DLGASVSEVTIEDGTTIDLLG------------------------SGSTPLHYAACGGNA 1089 GAS+++V ++ T + G++ LH AA G+ Sbjct: 477 KHGASITQVNEDEETALHRAAIGGQTGAVRQLLEWDIRLLLMKDEMGNSALHLAARSGHD 536 Query: 1090 VCCQLLIARGANLAAKNASGSTPLMVA 1170 ++L+ GA+ AKN+ TPL VA Sbjct: 537 ATTKVLLDNGADKEAKNSYQKTPLQVA 563 Score = 66.2 bits (160), Expect = 5e-10 Identities = 65/262 (24%), Positives = 115/262 (43%), Gaps = 36/262 (13%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLHYAA + + + L++ +++ + T L+ AC +G E++Q L+ N+N+ + Sbjct: 158 TPLHYAAMKSNFSALHALIKLKADVDAEDDNKMTPLLLACVHGSQEIIQELIKANSNVTK 217 Query: 715 TDY-LNGGTAIHFAALHGHARCLRLVL-ADYVPSIP--NFLNQTKHRSSEEVSDADFDDD 882 D LN T H AL G L +++ D V +I N N K + + + Sbjct: 218 RDQRLN--TVFHIVALRGEPEYLEMMMDHDPVEAIKALNLFNNEKKTPLRMAVEGNHPET 275 Query: 883 GLVKMVNWK-------ADGGLTPLHMAALNGHVECVQLLLDLGAS--------------- 996 L K++ + D +H AA G +E ++ L++ G + Sbjct: 276 -LKKILQMEKKNSCKWMDREKELIHFAAEKGFLEVLKALVEAGGNKNELNEVKAVPLHVA 334 Query: 997 --------VSEVTIEDGTTIDLLG-SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 VS + E+ ID++ G TPL A + C + LIA+ ANL + Sbjct: 335 AQMNQLEVVSYLIEEEKDNIDVVDEQGLTPLMMAVTHDSKKCVEYLIAKKANLTITDKDE 394 Query: 1150 STPLMVAHSWHR-NSIEEILSN 1212 TP+ + ++ +S+E IL + Sbjct: 395 RTPVFIGAKFNALSSVEYILDH 416 Score = 50.1 bits (118), Expect = 4e-05 Identities = 63/266 (23%), Positives = 107/266 (40%), Gaps = 1/266 (0%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 +AR+G++ + L P LA + G +PLHYAA G+++ V LLL N +N Sbjct: 39 SAREGNVNALQEALLKAP-LAVNAQDGDFMTPLHYAARYGNYDAVKLLLSKNALPNTKNR 97 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G T L A +Y ++G++ ++ D Sbjct: 98 EGDTPLHIASKY--------------------------------IYGYSDICSIIDEDQA 125 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 S + TK ++ +A ++ + VN LTPLH AA+ + + L+ Sbjct: 126 DSARKYNTATK-----KIINALVSENAEIDPVN---KYQLTPLHYAAMKSNFSALHALIK 177 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL- 1161 L A +V ED + TPL A G+ Q LI +N+ ++ +T Sbjct: 178 LKA---DVDAEDDNKM-------TPLLLACVHGSQEIIQELIKANSNVTKRDQRLNTVFH 227 Query: 1162 MVAHSWHRNSIEEILSNEPGGQIRTL 1239 +VA +E ++ ++P I+ L Sbjct: 228 IVALRGEPEYLEMMMDHDPVEAIKAL 253 Score = 43.1 bits (100), Expect = 0.005 Identities = 32/91 (35%), Positives = 48/91 (52%) Frame = +1 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 +AD + +H +A G+V +Q L L A ++ V +DG + TPLHYAA GN Sbjct: 28 EADNLRSIIHQSAREGNVNALQEAL-LKAPLA-VNAQDGDFM-------TPLHYAARYGN 78 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLMVAHSW 1179 +LL+++ A KN G TPL +A + Sbjct: 79 YDAVKLLLSKNALPNTKNREGDTPLHIASKY 109 Score = 35.8 bits (81), Expect = 0.74 Identities = 18/50 (36%), Positives = 27/50 (54%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLM 690 LH AA G+ IV + GV I+ R+ G+TA AC+ H +V + + Sbjct: 592 LHTAAFYGNESIVRYFIAEGVTIDRRDEEGKTAFDIACENDHKDVARAFL 641
>Q5DU14:MYO16_MOUSE Myosin-XVI - Mus musculus (Mouse)| Length = 1919 Score = 69.3 bits (168), Expect = 6e-11 Identities = 72/229 (31%), Positives = 103/229 (44%), Gaps = 5/229 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 S LH A + I +L++ GV +N ++ T + AC + ++V L+L AN+ Sbjct: 95 SLLHLCARYDNVFIAEVLIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLILAGANVFL 154 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTK-HRSSEEVSDA-DFDDDGL 888 D +NG + +A + + L D + L Q K R ++D F G Sbjct: 155 QD-VNGNIPLDYAVEGTESSAILLAYLDEKGVDLSSLRQIKLQRPLSMLTDVRHFLSSG- 212 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS---TP 1059 VN K D G+T LHMA +G+ E V LLL+ G DL G+ TP Sbjct: 213 -GDVNEKNDDGVTLLHMACASGYKEVVLLLLEHGG-------------DLNGTDDRYWTP 258 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 LH AA G +LL+A AN N +G P +A S SIEE+L Sbjct: 259 LHLAAKYGQTTLVKLLLAHQANPHLVNCNGEKPSDIAAS---ESIEEML 304
>Q9D2J7:ANKR5_MOUSE Ankyrin repeat domain-containing protein 5 - Mus musculus (Mouse)| Length = 775 Score = 69.3 bits (168), Expect = 6e-11 Identities = 75/280 (26%), Positives = 120/280 (42%), Gaps = 34/280 (12%) Frame = +1 Query: 433 RLVSAARDGDLQEARALLEYN-PRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 R++ R+ D ++ L P L ++ S LH A+ ++VS LL+ G Sbjct: 15 RVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHP 74 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAAL---HGHARCL 780 +++++ G T M+A + GH ++ L A++ D N G + F + H RC Sbjct: 75 DVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVD--NEGKGVLFYCILPTKRHYRC- 131 Query: 781 RLVLADYVPSIPNFLNQTKH---RSSEEVSDA-DFDDDGLVKMVNWKA---DGGLTPLHM 939 L+ ++ + N + K R+ EE D D L K N A G T L Sbjct: 132 SLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAINTSTGRTALME 191 Query: 940 AALNGHVECVQLLLDLGASVSEVTIE---------DGTTIDLLG--------------SG 1050 ++ G +E V+ +L+ G V+ + G D+L G Sbjct: 192 SSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDG 251 Query: 1051 STPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 +TPLH+AA GG A CC+ + RG +L KN TP +VA Sbjct: 252 NTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVA 291 Score = 45.1 bits (105), Expect = 0.001 Identities = 29/88 (32%), Positives = 49/88 (55%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 V+ K + TPL +A +G+++ V+ L++ GA+V+ T + L TPLH+A Sbjct: 518 VDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVN-------ATDNFLW---TPLHFACH 567 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPL 1161 G +LL+ GA++ A + + STPL Sbjct: 568 AGQQDIVELLVKAGASIDATSINNSTPL 595 Score = 38.1 bits (87), Expect = 0.15 Identities = 21/65 (32%), Positives = 33/65 (50%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PL A A G+ ++V L+E G +N + T L AC G ++V+ L+ A+I Sbjct: 527 TPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDA 586 Query: 715 TDYLN 729 T N Sbjct: 587 TSINN 591 Score = 37.4 bits (85), Expect = 0.26 Identities = 21/68 (30%), Positives = 40/68 (58%) Frame = +1 Query: 589 LESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGH 768 +E+G+ +++++ +T LM AC G+ +VV+ L+ AN++ TD T +HFA G Sbjct: 512 IETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFL-WTPLHFACHAGQ 570 Query: 769 ARCLRLVL 792 + L++ Sbjct: 571 QDIVELLV 578 Score = 37.4 bits (85), Expect = 0.26 Identities = 27/118 (22%), Positives = 53/118 (44%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L+ A G++ + L+E + F +PLH+A G +IV LL+++G I+ Sbjct: 529 LMIACASGNIDVVKFLIEKGANVNATDNFLW--TPLHFACHAGQQDIVELLVKAGASIDA 586 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 + T L +A + + V+ L+ A + + G A+ A + R + ++ Sbjct: 587 TSINNSTPLSRAIESCRLDTVKYLLDMGAKF-QIENRKGHAAMDIAKAYADYRIIDMI 643
>Q80YE7:DAPK1_MOUSE Death-associated protein kinase 1 - Mus musculus (Mouse)| Length = 1442 Score = 68.9 bits (167), Expect = 8e-11 Identities = 67/246 (27%), Positives = 111/246 (45%), Gaps = 1/246 (0%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L+ AA G++Q + L++ R+ GG N+ +++A+ GH + + L E+ +++ Sbjct: 383 LLIAAGCGNIQMLQLLIKRGSRIDVQDK-GGSNA-IYWASRHGHVDTLKFLNENKCPLDV 440 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 ++ G+TAL A +YGH +VVQ L F +N D T +H AA HG+ + + Sbjct: 441 KDKSGETALHVAARYGHADVVQLLCSFGSNPDFQD-KEEETPLHCAAWHGYYSVAKALCE 499 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 V N N+ S + D +V A+ G L+ + +GH+ Sbjct: 500 --VGCNVNIKNREGETPLLTASARGYHD-----IVECLAEHG-ADLNASDKDGHIALHLA 551 Query: 976 LLDLGASVSEVTIEDGTTIDLLG-SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGS 1152 + V + + G+ +D G+TPLH A G+A L NL N G Sbjct: 552 VRRCQMEVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIVVALCEASCNLDISNKYGR 611 Query: 1153 TPLMVA 1170 TPL +A Sbjct: 612 TPLHLA 617 Score = 66.2 bits (160), Expect = 5e-10 Identities = 50/187 (26%), Positives = 88/187 (47%), Gaps = 8/187 (4%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA G++ + L E G +N++N G+T L+ A G+ ++V+ L A+++ Sbjct: 480 TPLHCAAWHGYYSVAKALCEVGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNA 539 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 +D +G A+H A ++ +L +F++ + + A D + Sbjct: 540 SD-KDGHIALHLAVRRCQMEVIKTLLGH-----GSFVDFQDRHGNTPLHVACKDGSAPIV 593 Query: 895 MVNWKAD--------GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSG 1050 + +A G TPLH+AA NG ++ V+ L +GA+V +T DG T + L Sbjct: 594 VALCEASCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGANVEALT-SDGKTAEDLAKA 652 Query: 1051 STPLHYA 1071 H A Sbjct: 653 EQHEHVA 659 Score = 62.8 bits (151), Expect = 6e-09 Identities = 58/205 (28%), Positives = 85/205 (41%) Frame = +1 Query: 595 SGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR 774 S ++N N G L+ A G+ +++Q L+ + I D G AI++A+ HGH Sbjct: 368 SSYDVNQPNKHGTPPLLIAAGCGNIQMLQLLIKRGSRIDVQDK-GGSNAIYWASRHGHVD 426 Query: 775 CLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNG 954 L+ FLN+ K ++ K G T LH+AA G Sbjct: 427 TLK------------FLNENKCP------------------LDVKDKSGETALHVAARYG 456 Query: 955 HVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAA 1134 H + VQLL G++ E+ TPLH AA G + L G N+ Sbjct: 457 HADVVQLLCSFGSNPDFQDKEE----------ETPLHCAAWHGYYSVAKALCEVGCNVNI 506 Query: 1135 KNASGSTPLMVAHSWHRNSIEEILS 1209 KN G TPL+ A + + I E L+ Sbjct: 507 KNREGETPLLTASARGYHDIVECLA 531 Score = 40.4 bits (93), Expect = 0.030 Identities = 27/79 (34%), Positives = 37/79 (46%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 N+PLH A G IV L E+ +++ N G+T L A G +VV+ L L AN+ Sbjct: 578 NTPLHVACKDGSAPIVVALCEASCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGANVE 637 Query: 712 RTDYLNGGTAIHFAALHGH 768 +G TA A H Sbjct: 638 ALT-SDGKTAEDLAKAEQH 655
>Q07E28:CTTB2_NEONE Cortactin-binding protein 2 - Neofelis nebulosa (Clouded leopard)| Length = 1658 Score = 68.9 bits (167), Expect = 8e-11 Identities = 60/216 (27%), Positives = 90/216 (41%), Gaps = 1/216 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AA QG+ ++S+LL E G++IN +C+ GH Sbjct: 706 GRPTLLQQAATQGNVTLLSMLLNEEGLDINY-----------SCEDGH------------ 742 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 +A++ AA +GH C+RL+L + +V+ AD + Sbjct: 743 -----------SALYSAAKNGHTDCVRLLL----------------NAGAQVNAADTN-- 773 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 G TPL AA GH +CV+LL+ A+++ E G TPL Sbjct: 774 ------------GFTPLCAAAAQGHFKCVELLISYDANINHAADE----------GQTPL 811 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 + A GN C QLL+ G + + K G TP+ A Sbjct: 812 YLACKNGNKECIQLLLEAGTDRSVKTRDGWTPVHAA 847 Score = 64.7 bits (156), Expect = 1e-09 Identities = 66/234 (28%), Positives = 101/234 (43%), Gaps = 6/234 (2%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL +G ++N Sbjct: 711 LQQAATQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLNAGAQVNA 769 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH++ V+ L+ ++ANI H D G T ++ A +G+ C++L+L Sbjct: 770 ADTNGFTPLCAAAAQGHFKCVELLISYDANINHAAD--EGQTPLYLACKNGNKECIQLLL 827 Query: 793 -ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 A S+ T ++ + + D L ++ +A LH E V Sbjct: 828 EAGTDRSVKTRDGWTPVHAAVDTGNV----DSLKLLMYHRAPACRNSLH----EEESESV 879 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLG----SGSTPLHYAACGGNAVCCQLLIARG 1119 LD G E T + +L+ G T H AA G C ++L G Sbjct: 880 VFDLDQGEESPEGTSKPVVPAELINHADREGWTAAHIAASKGFKNCLEILCMHG 933
>Q5REW9:ANR27_PONPY Ankyrin repeat domain-containing protein 27 - Pongo pygmaeus| (Orangutan) Length = 1050 Score = 68.9 bits (167), Expect = 8e-11 Identities = 66/242 (27%), Positives = 97/242 (40%), Gaps = 40/242 (16%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNP--------------------------------RLARY 513 E+L+ A DGDL+ R LLE+ RLA+ Sbjct: 671 EKLLRAVADGDLEMVRYLLEWTEEDLEDAEDTVSAVDPEFCHPLCQCPKCAPAQKRLAKV 730 Query: 514 STFG--------GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHW 669 G +SPL+ AA G +++ LLL+ G RN L ACQ GH+ Sbjct: 731 PASGLGVNVTSQDGSSPLYVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHF 790 Query: 670 EVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSS 849 +VV+ L+ NA ++ D L+G T + +A GH + L+L +H ++ Sbjct: 791 QVVKCLLDSNAKPNKKD-LSGNTPLIYACSGGHHEVVALLL--------------QHGAA 835 Query: 850 EEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTT 1029 +N + G T LH A + HV V+LLL GASV + T Sbjct: 836 ----------------INTSNNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTA 879 Query: 1030 ID 1035 +D Sbjct: 880 VD 881 Score = 66.2 bits (160), Expect = 5e-10 Identities = 46/155 (29%), Positives = 68/155 (43%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 ++PLH AA G ++ LL+ G +N +Y G T L ACQ G+ V L+ + A+ Sbjct: 464 HTPLHVAALCGQASLIDLLVSKGAVVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAE 523 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 D NG T +H A +GH C++ ++ V S + K Sbjct: 524 VQDN-NGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEK------------------ 564 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGAS 996 G TPLH+AA G+ ++ LL GAS Sbjct: 565 ---------GDTPLHIAARWGYQAIIETLLQNGAS 590 Score = 54.7 bits (130), Expect = 2e-06 Identities = 45/153 (29%), Positives = 62/153 (40%), Gaps = 29/153 (18%) Frame = +1 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL----------------- 1041 D G TPLH+AAL G + LL+ GA V+ T + L Sbjct: 461 DRGHTPLHVAALCGQASLIDLLVSKGAVVNATDYHGATPLHLACQKGYQSVTLLLLHYKA 520 Query: 1042 ------GSGSTPLHYAACGGNAVCCQLLI---ARGANLAAKNASGSTPLMVAHSW-HRNS 1191 +G+TPLH A G+ C + L+ L N G TPL +A W ++ Sbjct: 521 SAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQAI 580 Query: 1192 IEEILSN--EPGGQIRTLPSPYLCLPLMSIMSI 1284 IE +L N P Q R +P C I+S+ Sbjct: 581 IETLLQNGASPEIQNRLKETPLKCALNSKILSV 613 Score = 54.7 bits (130), Expect = 2e-06 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 3/103 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH A +G+ + LLL +++ G T L AC YGH + V+ L+ ++ R Sbjct: 498 TPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCR 557 Query: 715 TDYLN--GGTAIHFAALHGHARCLRLVLADYV-PSIPNFLNQT 834 D N G T +H AA G+ + +L + P I N L +T Sbjct: 558 LDIGNEKGDTPLHIAARWGYQAIIETLLQNGASPEIQNRLKET 600 Score = 51.6 bits (122), Expect = 1e-05 Identities = 41/145 (28%), Positives = 61/145 (42%) Frame = +1 Query: 727 NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNW 906 +G + ++ AALHG A + L+L KH ++ +AD Sbjct: 743 DGSSPLYVAALHGRADLIPLLL--------------KHGANAGARNAD------------ 776 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 PLH+A GH + V+ LLD A ++ + SG+TPL YA GG+ Sbjct: 777 ----QAVPLHLACQQGHFQVVKCLLDSNAKPNKKDL----------SGNTPLIYACSGGH 822 Query: 1087 AVCCQLLIARGANLAAKNASGSTPL 1161 LL+ GA + N G+T L Sbjct: 823 HEVVALLLQHGAAINTSNNKGNTAL 847 Score = 37.4 bits (85), Expect = 0.26 Identities = 19/41 (46%), Positives = 25/41 (60%) Frame = +1 Query: 1048 GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 GS+PL+ AA G A LL+ GAN A+NA + PL +A Sbjct: 744 GSSPLYVAALHGRADLIPLLLKHGANAGARNADQAVPLHLA 784
>Q6RI86:TRPA1_RAT Transient receptor potential cation channel subfamily A member 1 -| Rattus norvegicus (Rat) Length = 1125 Score = 68.6 bits (166), Expect = 1e-10 Identities = 69/259 (26%), Positives = 114/259 (44%), Gaps = 17/259 (6%) Frame = +1 Query: 445 AARDGDLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLE-SGVEINL 615 AA ++ + LL NP L + +PLH A ++E++ +L E INL Sbjct: 106 AAEKNQVESVKFLLSQGANPNLRNRNMM----APLHIAVQGMYNEVIKVLTEHKATNINL 161 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 G TALM C + E +Q L+ A + +++ G +H AA G RC+ L+LA Sbjct: 162 EGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKW-GDYPVHQAAFSGAKRCMELILA 220 Query: 796 -----DYVPSIP-NFLNQTKHRSSE-EVSDADFDDDGLVKM-------VNWKADGGLTPL 933 Y NF+N K V D D ++KM ++ + L Sbjct: 221 YGEKTGYSREAHINFVNHKKASPLHLAVQSGDLD---MIKMCLDSGAHIDMMENAKCMAL 277 Query: 934 HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIA 1113 H AA G + V+L++ S++ +D G+ T LH A+ + LI+ Sbjct: 278 HFAATQGATDIVKLMISSYTGSSDIV----NAVD--GNQETLLHRASLFDHHDLADYLIS 331 Query: 1114 RGANLAAKNASGSTPLMVA 1170 GA++ + ++ G +PL++A Sbjct: 332 VGADINSTDSEGRSPLILA 350 Score = 62.4 bits (150), Expect = 7e-09 Identities = 40/115 (34%), Positives = 65/115 (56%), Gaps = 7/115 (6%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA GH ++V LLL+ G + L ++ G TAL A G+ + ++ ++ + N+ Sbjct: 485 TPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVIL--DTNLKC 541 Query: 715 TDYLN--GGTAIHFAALHGHARCLRLVLADYVPSIPN-----FLNQTKHRSSEEV 858 TD L+ G TA+HFAA GHA+ + ++L+ + N FL+ H +EV Sbjct: 542 TDRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEV 596 Score = 61.6 bits (148), Expect = 1e-08 Identities = 75/326 (23%), Positives = 125/326 (38%), Gaps = 65/326 (19%) Frame = +1 Query: 514 STFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQ-------------------- 633 ST SPL A A IV+LLL G +++++++ G+ Sbjct: 338 STDSEGRSPLILATASASWNIVNLLLSKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEF 397 Query: 634 ------------------TALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAAL 759 T L AC+ G V L+ FN ++H + + + +HFAA Sbjct: 398 LQMQHIKELVMDEDNDGCTPLHYACRQGAPVSVNNLLRFNVSVH-SKSKDKKSPLHFAAS 456 Query: 760 HGHAR-CLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLH 936 +G C RL+ +++SD ++G + G+TPLH Sbjct: 457 YGRINTCQRLL--------------------QDISDTRLLNEGDLH--------GMTPLH 488 Query: 937 MAALNGHVECVQLLLDLGA---------------------SVSEVTIEDG--TTIDLLGS 1047 +AA NGH + VQLLL GA +V ++ T L Sbjct: 489 LAAKNGHDKVVQLLLKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEE 548 Query: 1048 GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGG- 1224 G+T LH+AA G+A +L++ A++ S + H+ + + + ++ Sbjct: 549 GNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTIRSKRWDE 608 Query: 1225 --QIRTLPSPYLCLPLMSIMSIAREC 1296 Q+ T SP P+M ++ EC Sbjct: 609 CLQVFTHDSPSNRCPIMEMVEYLPEC 634 Score = 47.8 bits (112), Expect = 2e-04 Identities = 60/260 (23%), Positives = 99/260 (38%), Gaps = 34/260 (13%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH A G +++ + L+SG I++ AL A G ++V+ ++ ++ Sbjct: 242 SPLHLAVQSGDLDMIKMCLDSGAHIDMMENAKCMALHFAATQGATDIVK--LMISSYTGS 299 Query: 715 TDYLNG-----GTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 +D +N T +H A+L H LADY+ S+ +N T Sbjct: 300 SDIVNAVDGNQETLLHRASLFDHHD-----LADYLISVGADINSTDSE------------ 342 Query: 880 DGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVS----------EVTIED--- 1020 G +PL +A + V LLL GA V +T++ Sbjct: 343 -------------GRSPLILATASASWNIVNLLLSKGAKVDIKDHLGRNFLHLTVQQPYG 389 Query: 1021 ---------------GTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGST 1155 +D G TPLHYA G V L+ ++ +K+ + Sbjct: 390 LRNLRPEFLQMQHIKELVMDEDNDGCTPLHYACRQGAPVSVNNLLRFNVSVHSKSKDKKS 449 Query: 1156 PLMVAHSWHR-NSIEEILSN 1212 PL A S+ R N+ + +L + Sbjct: 450 PLHFAASYGRINTCQRLLQD 469 Score = 47.4 bits (111), Expect = 2e-04 Identities = 32/106 (30%), Positives = 52/106 (49%) Frame = +1 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAV 1092 D L LH AA G VE +QL+++ G+S + + D G+TPLH+AA Sbjct: 62 DENLCLLHHAAAEGQVELMQLIIN-GSSCEALNVMDDY-------GNTPLHWAAEKNQVE 113 Query: 1093 CCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQI 1230 + L+++GAN +N + PL +A N + ++L+ I Sbjct: 114 SVKFLLSQGANPNLRNRNMMAPLHIAVQGMYNEVIKVLTEHKATNI 159
>P53355:DAPK1_HUMAN Death-associated protein kinase 1 - Homo sapiens (Human)| Length = 1432 Score = 68.6 bits (166), Expect = 1e-10 Identities = 60/221 (27%), Positives = 105/221 (47%), Gaps = 13/221 (5%) Frame = +1 Query: 424 SGERLVS-AARDG--DLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLL 588 SGE + AAR G D+ + + L + NP + +PLH AA G++ + L Sbjct: 444 SGEMALHVAARYGHADVAQVQVLCSFGSNPNIQDKE----EETPLHCAAWHGYYSVAKAL 499 Query: 589 LESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGH 768 E+G +N++N G+T L+ A G+ ++V+ L A+++ D +G A+H A Sbjct: 500 CEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACD-KDGHIALHLAVRRCQ 558 Query: 769 ARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKAD--------GGL 924 ++ +L+ F++ + + A D + + + +A+ G Sbjct: 559 MEVIKTLLSQGC-----FVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGR 613 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS 1047 TPLH+AA NG ++ V+ L +GASV +T + T DL S Sbjct: 614 TPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARS 654 Score = 62.0 bits (149), Expect = 1e-08 Identities = 73/257 (28%), Positives = 114/257 (44%), Gaps = 12/257 (4%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L+ AA G++Q + L++ R+ GG N+ +++AA GH + + L E+ +++ Sbjct: 383 LLIAAGCGNIQILQLLIKRGSRIDVQDK-GGSNA-VYWAARHGHVDTLKFLSENKCPLDV 440 Query: 616 RNYRGQTALMQACQYGHWEV--VQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLR-L 786 ++ G+ AL A +YGH +V VQ L F +N + D T +H AA HG+ + L Sbjct: 441 KDKSGEMALHVAARYGHADVAQVQVLCSFGSNPNIQD-KEEETPLHCAAWHGYYSVAKAL 499 Query: 787 VLADYVPSIPNFLNQTK---------HRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHM 939 A +I N +T H E +++ D + K DG + LH+ Sbjct: 500 CEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDK------DGHIA-LHL 552 Query: 940 AALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG 1119 A +E ++ LL G V +D G+TPLH A GN L Sbjct: 553 AVRRCQMEVIKTLLSQGCFVD---YQD-------RHGNTPLHVACKDGNMPIVVALCEAN 602 Query: 1120 ANLAAKNASGSTPLMVA 1170 NL N G TPL +A Sbjct: 603 CNLDISNKYGRTPLHLA 619 Score = 55.5 bits (132), Expect = 9e-07 Identities = 53/207 (25%), Positives = 83/207 (40%), Gaps = 2/207 (0%) Frame = +1 Query: 595 SGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR 774 S ++N N G L+ A G+ +++Q L+ + I D G A+++AA HGH Sbjct: 368 SNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDK-GGSNAVYWAARHGHVD 426 Query: 775 CLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNG 954 L+ + + P ++ K G LH+AA G Sbjct: 427 TLKFLSENKCP------------------------------LDVKDKSGEMALHVAARYG 456 Query: 955 HVEC--VQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANL 1128 H + VQ+L G++ + E+ TPLH AA G + L G N+ Sbjct: 457 HADVAQVQVLCSFGSNPNIQDKEE----------ETPLHCAAWHGYYSVAKALCEAGCNV 506 Query: 1129 AAKNASGSTPLMVAHSWHRNSIEEILS 1209 KN G TPL+ A + + I E L+ Sbjct: 507 NIKNREGETPLLTASARGYHDIVECLA 533 Score = 34.3 bits (77), Expect = 2.2 Identities = 27/90 (30%), Positives = 38/90 (42%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A +DG++ AL E N L + +G +PLH AA G ++V L G + Sbjct: 586 ACKDGNMPIVVALCEANCNLDISNKYG--RTPLHLAANNGILDVVRYLCLMGASVEALTT 643 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHR 714 G+TA A H V L + HR Sbjct: 644 DGKTAEDLARSEQHEHVAGLLARLRKDTHR 673
>Q07DV1:CTTB2_AOTNA Cortactin-binding protein 2 - Aotus nancymaae (Ma's night monkey)| Length = 1649 Score = 68.6 bits (166), Expect = 1e-10 Identities = 61/216 (28%), Positives = 92/216 (42%), Gaps = 1/216 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AAAQG+ ++S+LL E G++IN +C+ GH Sbjct: 709 GRPTLLQQAAAQGNVTLLSMLLNEEGLDINY-----------SCEDGH------------ 745 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 +A++ AA +GH C+RL+L+ + +V+ AD Sbjct: 746 -----------SALYSAAKNGHTDCVRLLLS----------------AEAQVNAAD---- 774 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 G TPL AA GH +CV+LL+ A+++ DG G TPL Sbjct: 775 ----------KNGFTPLCAAAAQGHFKCVELLIAYDANINHAA--DG--------GQTPL 814 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 + A GN C +LL+ G + + K G TP+ A Sbjct: 815 YLACKNGNKECIKLLLEAGTDRSVKTTDGWTPVHAA 850 Score = 66.6 bits (161), Expect = 4e-10 Identities = 62/215 (28%), Positives = 91/215 (42%), Gaps = 15/215 (6%) Frame = +1 Query: 406 SFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSL 585 ++ C L SAA++G R LL ++ G +PL AAAQGH + V L Sbjct: 738 NYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGF--TPLCAAAAQGHFKCVEL 795 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN--IHRTDYLNGGTAIHFAAL 759 L+ IN GQT L AC+ G+ E ++ L+ + + TD G T +H A Sbjct: 796 LIAYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTTD---GWTPVHAAVD 852 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG-------------LVKMV 900 G+ L+L++ VP+ N S EE FD DG ++ Sbjct: 853 TGNVDSLKLLMYHRVPAHGNSF------SEEESESGVFDLDGGEESPEGKSKPVVTADLI 906 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSE 1005 N G T H+AA G C+++L G +E Sbjct: 907 NHANREGWTAAHIAASKGFKNCLEILCRHGGLETE 941 Score = 65.1 bits (157), Expect = 1e-09 Identities = 70/256 (27%), Positives = 103/256 (40%), Gaps = 28/256 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL + ++N Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLSAEAQVNA 772 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH++ V+ L+ ++ANI H D G T ++ A +G+ C++L+L Sbjct: 773 ADKNGFTPLCAAAAQGHFKCVELLIAYDANINHAAD--GGQTPLYLACKNGNKECIKLLL 830 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 + G + V K G TP+H A G+V+ ++ Sbjct: 831 ----------------------------EAGTDRSV--KTTDGWTPVHAAVDTGNVDSLK 860 Query: 973 LLL-----DLGASVSEVTIEDG------------------TTIDLLG----SGSTPLHYA 1071 LL+ G S SE E G T DL+ G T H A Sbjct: 861 LLMYHRVPAHGNSFSEEESESGVFDLDGGEESPEGKSKPVVTADLINHANREGWTAAHIA 920 Query: 1072 ACGGNAVCCQLLIARG 1119 A G C ++L G Sbjct: 921 ASKGFKNCLEILCRHG 936
>Q9GZV1:ANKR2_HUMAN Ankyrin repeat domain-containing protein 2 - Homo sapiens (Human)| Length = 333 Score = 68.6 bits (166), Expect = 1e-10 Identities = 60/233 (25%), Positives = 98/233 (42%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA +G +++ L G + + +TAL +A GH E+++ L+ A + D L+ Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 TA+H+A GH ++L+ + H + V D K+++ Sbjct: 188 C-TAMHWACRGGHLEVVKLLQS--------------HGADTNVRD---------KLLS-- 221 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA 1089 TPLH+A G VE V+ L LG ++ E G T LH A Sbjct: 222 -----TPLHVAVRTGQVEIVEHFLSLGLEINARDRE----------GDTALHDAVRLNRY 266 Query: 1090 VCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSP 1248 +LL+ GA++ KN +G TP + W ++ + EPG + L P Sbjct: 267 KIIKLLLLHGADMMTKNLAGKTPTDLVQLWQADTRHALEHPEPGAEHNGLEGP 319 Score = 48.9 bits (115), Expect = 8e-05 Identities = 46/171 (26%), Positives = 73/171 (42%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 R + LH A+ +GH EI+ LL++G ++ ++ TA+ AC+ GH EVV+ L A+ Sbjct: 154 RRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADT 213 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + D L T +H A G V + +FL+ L Sbjct: 214 NVRDKLL-STPLHVAVRTGQ-----------VEIVEHFLS-------------------L 242 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +N + G T LH A + ++LLL GA + + T DL+ Sbjct: 243 GLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTPTDLV 293
>Q17QS6:ASB5_BOVIN Ankyrin repeat and SOCS box protein 5 - Bos taurus (Bovine)| Length = 329 Score = 68.2 bits (165), Expect = 1e-10 Identities = 67/231 (29%), Positives = 99/231 (42%), Gaps = 7/231 (3%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA+QG + LL G +N T L +AC H +TL+ AN++ Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTIDHVTPLHEACLGDHVACARTLLQAGANVNA 131 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLA-DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 ++G T + A G C L+L P + + L H ++ + + L Sbjct: 132 IT-IDGVTPLFNACSQGSTSCTELLLEYGAKPQLESCLPSPTHEAASK-----GHHECLE 185 Query: 892 KMVNWKADGGL------TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGS 1053 +++W D TPL++A ++ CV+ LL GA V + D Sbjct: 186 ILISWGVDVDQDIPHLGTPLYVACMSQQFHCVRKLLYAGADVQKGKYWD----------- 234 Query: 1054 TPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 TPLH AA LL+ GA++ AKN P+ VA S NS+ E L Sbjct: 235 TPLHAAAQQSCTEIVNLLLEFGADINAKNTDLLRPVDVATS---NSLVERL 282 Score = 52.8 bits (125), Expect = 6e-06 Identities = 32/96 (33%), Positives = 46/96 (47%) Frame = +1 Query: 922 LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQ 1101 +TPLH A L HV C + LL GA+V+ +TI+ G TPL A G+ C + Sbjct: 104 VTPLHEACLGDHVACARTLLQAGANVNAITID----------GVTPLFNACSQGSTSCTE 153 Query: 1102 LLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILS 1209 LL+ GA ++ S A H +E ++S Sbjct: 154 LLLEYGAKPQLESCLPSPTHEAASKGHHECLEILIS 189 Score = 35.4 bits (80), Expect = 0.97 Identities = 17/30 (56%), Positives = 22/30 (73%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 ++PLH AA Q EIV+LLLE G +IN +N Sbjct: 234 DTPLHAAAQQSCTEIVNLLLEFGADINAKN 263
>Q7S3M5:AKR1_NEUCR Palmitoyltransferase AKR1 - Neurospora crassa| Length = 729 Score = 68.2 bits (165), Expect = 1e-10 Identities = 74/272 (27%), Positives = 109/272 (40%), Gaps = 7/272 (2%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 ++ AR GD+ L A YS G +PLH+AA + + L++ G EIN Sbjct: 47 IMQMARVGDITGMEKLFAAGEYDATYSDDEGI-TPLHWAAINNQYAMCKFLIDKGAEINK 105 Query: 616 RNYRG-QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 + T L A Q H+ V L+ A+ TD G +H + +G+ + L+L Sbjct: 106 KGGESVATPLQWAAQRCHYYTVHLLLQHGADPLITDS-QGYNTLHISTFNGNVLLIVLLL 164 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 +P +V DA G T L +A G CV Sbjct: 165 HQGIPV--------------DVEDAY----------------GHTALMWSAYKGFPACVD 194 Query: 973 LLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGS 1152 + L GASV + G T LH+A G+ C Q LI GA+ AK A+G Sbjct: 195 VFLRWGASVHAKDEQ----------GFTALHWALVKGSPGCIQKLIEYGADRFAKTANGK 244 Query: 1153 TPLMVAH------SWHRNSIEEILSNEPGGQI 1230 TP + A +W + +++E +E G I Sbjct: 245 TPAITAQELNTVAAWQK-ALDECGYDEHGNAI 275
>Q68LP1:MIB2_RAT E3 ubiquitin-protein ligase MIB2 - Rattus norvegicus (Rat)| Length = 971 Score = 67.8 bits (164), Expect = 2e-10 Identities = 71/269 (26%), Positives = 113/269 (42%), Gaps = 9/269 (3%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G ++ R LL+ + G N+ LHY A E LLL +G ++ +N Sbjct: 486 AAYLGQVELVRLLLQARASVDLLDEEG--NTALHYTAMGNQPEATRLLLSAGCGVDAQNG 543 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 TAL A Q G EVV+ L +++ D + T +H A G + + V Sbjct: 544 TRSTALHVAVQRGFLEVVKILCEHGCDVNLPD-AHADTPLHSAISAGAGASSIVEVLTEV 602 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLV---------KMVNWKADGGLTPLHMAALNGH 957 P I + T + + A L ++V+ K + G T LH+AALN H Sbjct: 603 PGID--VTATNSQGFTLLHHASLKGHVLAVRKILARARQLVDAKKEDGFTALHLAALNNH 660 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 E Q+L+ G +V + + +PLH A + LL+ G N+ + Sbjct: 661 REVAQVLIREGR--CDVNVRNRKL-------QSPLHLAVQQAHLGLVPLLVDAGCNVNTE 711 Query: 1138 NASGSTPLMVAHSWHRNSIEEILSNEPGG 1224 + G T L VA R+ + ++++ GG Sbjct: 712 DEEGDTALHVA--LQRHQLLPLVADRAGG 738 Score = 50.4 bits (119), Expect = 3e-05 Identities = 45/122 (36%), Positives = 59/122 (48%), Gaps = 1/122 (0%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLG-SGSTPLHYAACGGNAVC 1095 G T L +AA G VE V+LLL ASV DLL G+T LHY A G Sbjct: 479 GRTALQVAAYLGQVELVRLLLQARASV-----------DLLDEEGNTALHYTAMGNQPEA 527 Query: 1096 CQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPYLCLPLMSI 1275 +LL++ G + A+N + ST L VA + +IL E G + LP + PL S Sbjct: 528 TRLLLSAGCGVDAQNGTRSTALHVAVQRGFLEVVKILC-EHGCDV-NLPDAHADTPLHSA 585 Query: 1276 MS 1281 +S Sbjct: 586 IS 587
>Q5KP49:AKR1_CRYNE Palmitoyltransferase AKR1 - Cryptococcus neoformans (Filobasidiella| neoformans) Length = 776 Score = 67.8 bits (164), Expect = 2e-10 Identities = 70/240 (29%), Positives = 96/240 (40%), Gaps = 3/240 (1%) Frame = +1 Query: 448 ARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEIN-LRNY 624 A+ GD A+L+ NP L + +PLH+AA H LL++SG +I+ + Sbjct: 77 AQRGDTAAIAAMLQENPSLNLSARDAQDVTPLHWAAINAHMGTCRLLIDSGADIDAIGGE 136 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNA--NIHRTDYLNGGTAIHFAALHGHARCLRLVLAD 798 T L A + GH VV L+ A NIH + N LH L Sbjct: 137 LKATPLQWAARNGHLYVVHLLISRGADPNIHDSQGFN--------TLH---------LIT 179 Query: 799 YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLL 978 + ++ L + + D D G T L AA G V LL Sbjct: 180 HSSAVMPLLYMLHQPVAIDEKDTD----------------GHTALMWAAYQGDALSVDLL 223 Query: 979 LDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTP 1158 + GASV+ +G TPLH+AA GN V L+ GA+L AK +G TP Sbjct: 224 IRHGASVNSTD----------NAGMTPLHWAAVKGNKVSIMHLVEAGASLDAKEEAGKTP 273 Score = 42.0 bits (97), Expect = 0.010 Identities = 43/165 (26%), Positives = 64/165 (38%), Gaps = 23/165 (13%) Frame = +1 Query: 736 TAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKAD 915 T +H+AA++ H RL++ S AD D G + Sbjct: 106 TPLHWAAINAHMGTCRLLID---------------------SGADIDAIG--------GE 136 Query: 916 GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLG----------------- 1044 TPL AA NGH+ V LL+ GA + + T+ L+ Sbjct: 137 LKATPLQWAARNGHLYVVHLLISRGADPNIHDSQGFNTLHLITHSSAVMPLLYMLHQPVA 196 Query: 1045 ------SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL 1161 G T L +AA G+A+ LLI GA++ + + +G TPL Sbjct: 197 IDEKDTDGHTALMWAAYQGDALSVDLLIRHGASVNSTDNAGMTPL 241
>Q495B1:AKD1A_HUMAN Ankyrin repeat and death domain-containing protein 1A precursor -| Homo sapiens (Human) Length = 423 Score = 67.8 bits (164), Expect = 2e-10 Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 9/230 (3%) Frame = +1 Query: 544 HYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDY 723 H AA G + + L+ SG + N+++ G TAL A GH V+Q L+ ++ + Sbjct: 73 HRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQN- 131 Query: 724 LNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQ--------TKHRSSEEVSDADFDD 879 G TA+H AA H C++L+L S N L Q SE+VS Sbjct: 132 AEGLTALHSAAGGSHPDCVQLLLR--AGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHA 189 Query: 880 DGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTP 1059 G +V+ + G +PLH+A + V+LL++ + V+ V TP Sbjct: 190 GGCANVVDHQ---GASPLHLAVRHNFPALVRLLINSDSDVNAVD----------NRQQTP 236 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA-HSWHRNSIEEIL 1206 LH AA +L+ G +L ++ G T L VA S H + ++ I+ Sbjct: 237 LHLAAEHAWQDIADMLLIAGVDLNLRDKQGKTALAVAVRSNHVSLVDMII 286 Score = 65.5 bits (158), Expect = 9e-10 Identities = 63/225 (28%), Positives = 104/225 (46%), Gaps = 8/225 (3%) Frame = +1 Query: 562 GHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLM--LFNANIHRTDYLNGG 735 GH I+ +L+ SG +I+ + G T L A Q GH V+ +M L + + D L G Sbjct: 11 GHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKL-GR 69 Query: 736 TAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKAD 915 TA H AA HG L ++ + + + ++ ++ L ++V+ D Sbjct: 70 TAFHRAAEHGQLDALDFLVGS---GCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLD 126 Query: 916 ------GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 GLT LH AA H +CVQLLL G++V+ +T ++ + LHYAA Sbjct: 127 LEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKN----------LSCLHYAAL 176 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSN 1212 G+ ++LI G + G++PL +A + ++ +L N Sbjct: 177 SGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLIN 221 Score = 42.7 bits (99), Expect = 0.006 Identities = 20/54 (37%), Positives = 34/54 (62%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLM 690 + +PLH AA +I +LL +GV++NLR+ +G+TAL A + H +V ++ Sbjct: 233 QQTPLHLAAEHAWQDIADMLLIAGVDLNLRDKQGKTALAVAVRSNHVSLVDMII 286
>Q9J4Z5:V245_FOWPV Putative ankyrin repeat protein FPV245 - Fowlpox virus (FPV)| Length = 436 Score = 67.4 bits (163), Expect = 2e-10 Identities = 62/228 (27%), Positives = 113/228 (49%), Gaps = 14/228 (6%) Frame = +1 Query: 571 EIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHF 750 E++ +L+SGV++N +N + +T L A + EV++ L + A+++ D NG IH Sbjct: 105 EMIKTILDSGVKVNTKNAKSKTFLHYAIKNNDLEVIKMLFEYGADVNIKDD-NGCYPIHI 163 Query: 751 AALHGHARCLRLVL--ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV-------N 903 A ++L+L Y N+ N H + A + D +K+V + Sbjct: 164 ATRSNSYEIIKLLLEKGAYANVKDNYGNSPLHNA------AKYGDYACIKLVLDHTNNIS 217 Query: 904 WKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYA---A 1074 K + G+TPLH A L V+LL++ S+++ ++ G TPLHYA Sbjct: 218 NKCNNGVTPLHNAILYNR-SAVELLIN-NRSINDTDVD----------GYTPLHYALQPP 265 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW-HRNS-IEEILSN 1212 C + + +L+ A+++ K+ +G P+ A + +R+S I+E+L+N Sbjct: 266 CSIDII--DILLYNNADISIKDNNGRNPIDTAFKYINRDSVIKELLAN 311 Score = 48.9 bits (115), Expect = 8e-05 Identities = 46/187 (24%), Positives = 77/187 (41%), Gaps = 1/187 (0%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A ++ DL+ + L EY + G P+H A +EI+ LLLE G N+++ Sbjct: 131 AIKNNDLEVIKMLFEYGADVNIKDDNGCY--PIHIATRSNSYEIIKLLLEKGAYANVKDN 188 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G + L A +YG + ++ L+L + N NG T +H A L+ + L+ Sbjct: 189 YGNSPLHNAAKYGDYACIK-LVLDHTNNISNKCNNGVTPLHNAILYNRSAVELLI----- 242 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNG-HVECVQLLL 981 ++ ++D D D G TPLH A ++ + +LL Sbjct: 243 -------------NNRSINDTDVD--------------GYTPLHYALQPPCSIDIIDILL 275 Query: 982 DLGASVS 1002 A +S Sbjct: 276 YNNADIS 282
>Q05921:RN5A_MOUSE 2-5A-dependent ribonuclease - Mus musculus (Mouse)| Length = 735 Score = 67.4 bits (163), Expect = 2e-10 Identities = 78/287 (27%), Positives = 122/287 (42%), Gaps = 30/287 (10%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRL-ARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEIN 612 L+ A + GD+ + LLE A T+G +PLH A G +IV+LLL G + + Sbjct: 29 LIKAVQKGDVVRVQQLLEKGADANACEDTWGW--TPLHNAVQAGRVDIVNLLLSHGADPH 86 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 R G T + A G ++++ L+ A+++ D NG TA AA G+A LR + Sbjct: 87 RRKKNGATPFIIAGIQGDVKLLEILLSCGADVNECDE-NGFTAFMEAAERGNAEALRFLF 145 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 A + N QT K GG T L AA GH+E ++ Sbjct: 146 AK--GANVNLRRQT------------------TKDKRRLKQGGATALMSAAEKGHLEVLR 185 Query: 973 LLL-DLGASV--------------------------SEVTIEDGTTIDLLGS-GSTPLHY 1068 +LL D+ A V + + I+ G +++ G G TPL Sbjct: 186 ILLNDMKAEVDARDNMGRNALIRTLLNWDCENVEEITSILIQHGADVNVRGERGKTPLIA 245 Query: 1069 AACGGNAVCCQLLIAR-GANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 A + Q+L++R G N+ A++ G T L++A I ++L Sbjct: 246 AVERKHTGLVQMLLSREGINIDARDNEGKTALLIAVDKQLKEIVQLL 292 Score = 40.0 bits (92), Expect = 0.039 Identities = 49/209 (23%), Positives = 80/209 (38%), Gaps = 10/209 (4%) Frame = +1 Query: 634 TALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSI 813 ++L++A Q G VQ L+ A+ + + G T +H A G + L+L+ Sbjct: 27 SSLIKAVQKGDVVRVQQLLEKGADANACEDTWGWTPLHNAVQAGRVDIVNLLLSH----- 81 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 HR + G TP +A + G V+ +++LL GA Sbjct: 82 ----GADPHRRKKN---------------------GATPFIIAGIQGDVKLLEILLSCGA 116 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNAS--------- 1146 V+E +G T AA GNA + L A+GAN+ + + Sbjct: 117 DVNECD----------ENGFTAFMEAAERGNAEALRFLFAKGANVNLRRQTTKDKRRLKQ 166 Query: 1147 -GSTPLMVAHSWHRNSIEEILSNEPGGQI 1230 G+T LM A + IL N+ ++ Sbjct: 167 GGATALMSAAEKGHLEVLRILLNDMKAEV 195 Score = 37.0 bits (84), Expect = 0.33 Identities = 55/204 (26%), Positives = 74/204 (36%), Gaps = 12/204 (5%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYR----------GQTALMQACQYGHWEVVQTLML-F 696 AA +G+ E + L G +NLR G TALM A + GH EV++ L+ Sbjct: 132 AAERGNAEALRFLFAKGANVNLRRQTTKDKRRLKQGGATALMSAAEKGHLEVLRILLNDM 191 Query: 697 NANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFD 876 A + D + I R L + V I + L Q AD Sbjct: 192 KAEVDARDNMGRNALI---------RTLLNWDCENVEEITSILIQ---------HGAD-- 231 Query: 877 DDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL-GSGS 1053 VN + + G TPL A H VQ+LL +G ID G Sbjct: 232 -------VNVRGERGKTPLIAAVERKHTGLVQMLLS----------REGINIDARDNEGK 274 Query: 1054 TPLHYAACGGNAVCCQLLIARGAN 1125 T L A QLL+ +GA+ Sbjct: 275 TALLIAVDKQLKEIVQLLLEKGAD 298
>Q923M0:PP16A_MOUSE Protein phosphatase 1 regulatory subunit 16A - Mus musculus (Mouse)| Length = 524 Score = 67.4 bits (163), Expect = 2e-10 Identities = 71/257 (27%), Positives = 104/257 (40%), Gaps = 13/257 (5%) Frame = +1 Query: 436 LVSAARDGDLQEARALLE--YNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 L+ AA DL+E R L +P LA + LH E+ LL++G ++ Sbjct: 75 LLEAAARNDLEEVRQFLTSGVSPNLANEDGL----TALHQCCIDDFQEMAQQLLDAGADV 130 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 N R+ T L A GH +V+ L+ A++ + +G CL Sbjct: 131 NARDSECWTPLHAAATCGHLHLVELLISRGADLLAVNS-DGNMPYDLCEDAQTLDCLETA 189 Query: 790 LADY---------VPSIPNF--LNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLH 936 +A+ ++P LN ++R + +D D G T LH Sbjct: 190 MANQGITQEGIEEARAVPELCMLNDLQNRLQAGANLSD------------PLDHGATLLH 237 Query: 937 MAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIAR 1116 +AA NG E LLL+ GAS+S + G PLH AA G +LL+A Sbjct: 238 IAAANGFSEVATLLLEQGASLSAKDHD----------GWEPLHAAAYWGQVHLVELLVAH 287 Query: 1117 GANLAAKNASGSTPLMV 1167 GA+L K+ TPL V Sbjct: 288 GADLNGKSLVDETPLDV 304
>Q8K4M9:OSBL1_RAT Oxysterol-binding protein-related protein 1 - Rattus norvegicus (Rat)| Length = 950 Score = 67.4 bits (163), Expect = 2e-10 Identities = 63/222 (28%), Positives = 96/222 (43%), Gaps = 19/222 (8%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFG--GRN------SPLHYAAAQGHHEIVSL 585 ++L+ AR+G+ +E R LLE R + GR+ +PLH A GH ++V Sbjct: 7 QQLLHHARNGNAEEVRKLLEAMARAEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVQD 66 Query: 586 LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHG 765 LL++G ++N+ N G T L +A G E+V L+ +NA+ T +NG A H Sbjct: 67 LLKAGAKVNMLNDMGDTPLHRAAFTGRKELVMLLLEYNAD---TTVVNGSGQTAKEATHD 123 Query: 766 HARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM-----------VNWKA 912 + + + +T+ R EE+ + ++ VN Sbjct: 124 KE----------IRQMLEAVERTQQRKLEELLLGAAREGRTAEVSALLSRPNPPDVNCSD 173 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 G TPLH AA H +CV LL GA S D +DL Sbjct: 174 QLGNTPLHCAAYRAHKQCVLKLLRSGADPSLKNKNDQKPLDL 215 Score = 42.7 bits (99), Expect = 0.006 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEY-NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE 606 E L+ AAR+G E ALL NP S G N+PLH AA + H + V LL SG + Sbjct: 143 ELLLGAAREGRTAEVSALLSRPNPPDVNCSDQLG-NTPLHCAAYRAHKQCVLKLLRSGAD 201 Query: 607 INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +L+N Q L H ++ +++ N +H+ Sbjct: 202 PSLKNKNDQKPL----DLAHGTEMKHILVGNKVVHK 233 Score = 34.7 bits (78), Expect = 1.7 Identities = 26/73 (35%), Positives = 32/73 (43%) Frame = +1 Query: 943 ALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGA 1122 A NG+ E V+ LL+ A V D G TPLH A G+ Q L+ GA Sbjct: 13 ARNGNAEEVRKLLEAMARAEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVQDLLKAGA 72 Query: 1123 NLAAKNASGSTPL 1161 + N G TPL Sbjct: 73 KVNMLNDMGDTPL 85
>Q8WWX0:ASB5_HUMAN Ankyrin repeat and SOCS box protein 5 - Homo sapiens (Human)| Length = 329 Score = 67.4 bits (163), Expect = 2e-10 Identities = 65/235 (27%), Positives = 98/235 (41%), Gaps = 11/235 (4%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA+QG + LL G +N T L +AC H +TL+ AN++ Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 131 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVL-----ADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 ++G T + A G C L+L A +P+ ++ + E D Sbjct: 132 IT-IDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLPSPTHEAASKGHHECLDI---- 186 Query: 880 DGLVKMVNWKADGGL------TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +++W D TPL++A ++ C+ LL GA V + D Sbjct: 187 -----LISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWD------- 234 Query: 1042 GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 TPLH AA + LL+ GA++ AKN P+ VA S + +E IL Sbjct: 235 ----TPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATS--SSMVERIL 283 Score = 55.8 bits (133), Expect = 7e-07 Identities = 41/131 (31%), Positives = 61/131 (46%), Gaps = 1/131 (0%) Frame = +1 Query: 922 LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQ 1101 +TPLH A L HV C + LL+ GA+V+ +TI+ G TPL A G+ C + Sbjct: 104 VTPLHEACLGDHVACARTLLEAGANVNAITID----------GVTPLFNACSQGSPSCAE 153 Query: 1102 LLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPYLCLPL-MSIM 1278 LL+ GA ++ S A H ++ ++S G P+L PL ++ M Sbjct: 154 LLLEYGAKAQLESCLPSPTHEAASKGHHECLDILIS---WGIDVDQEIPHLGTPLYVACM 210 Query: 1279 SIARECGWRYL 1311 S C W+ L Sbjct: 211 SQQFHCIWKLL 221 Score = 48.1 bits (113), Expect = 1e-04 Identities = 33/119 (27%), Positives = 54/119 (45%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L +A G A LLEY + S SP H AA++GHHE + +L+ G++++ Sbjct: 140 LFNACSQGSPSCAELLLEYGAKAQLESCLP---SPTHEAASKGHHECLDILISWGIDVDQ 196 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 T L AC + + L+ A++ + Y + T +H AA + L+L Sbjct: 197 EIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWD--TPLHAAAQQSSTEIVNLLL 253 Score = 36.2 bits (82), Expect = 0.57 Identities = 17/30 (56%), Positives = 22/30 (73%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 ++PLH AA Q EIV+LLLE G +IN +N Sbjct: 234 DTPLHAAAQQSSTEIVNLLLEFGADINAKN 263
>A0M8T5:CTTB2_FELCA Cortactin-binding protein 2 - Felis silvestris catus (Cat)| Length = 1658 Score = 67.0 bits (162), Expect = 3e-10 Identities = 59/216 (27%), Positives = 90/216 (41%), Gaps = 1/216 (0%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLL-ESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GR + L AA QG+ ++S+LL E G++IN +C+ GH Sbjct: 706 GRPTLLQQAATQGNVTLLSMLLNEEGLDINY-----------SCEDGH------------ 742 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 +A++ AA +GH C+RL+L + +V+ AD + Sbjct: 743 -----------SALYSAAKNGHTDCVRLLL----------------NAGAQVNAADTN-- 773 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 G TPL AA GH +CV+LL+ A+++ E G TPL Sbjct: 774 ------------GFTPLCAAAAQGHFKCVELLISYDANINHAADE----------GQTPL 811 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 + A G+ C QLL+ G + + K G TP+ A Sbjct: 812 YLACKNGSKECIQLLLEAGTDRSVKTRDGWTPVHAA 847 Score = 63.9 bits (154), Expect = 3e-09 Identities = 66/234 (28%), Positives = 100/234 (42%), Gaps = 6/234 (2%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G++ LL YS G +S L+ AA GH + V LLL +G ++N Sbjct: 711 LQQAATQGNVTLLSMLLNEEGLDINYSCEDG-HSALYSAAKNGHTDCVRLLLNAGAQVNA 769 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G T L A GH++ V+ L+ ++ANI H D G T ++ A +G C++L+L Sbjct: 770 ADTNGFTPLCAAAAQGHFKCVELLISYDANINHAAD--EGQTPLYLACKNGSKECIQLLL 827 Query: 793 -ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 A S+ T ++ + + D L ++ +A LH E V Sbjct: 828 EAGTDRSVKTRDGWTPVHAAVDTGNV----DSLKLLMYHRAPACRNSLH----EEESESV 879 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLG----SGSTPLHYAACGGNAVCCQLLIARG 1119 LD G E T + +L+ G T H AA G C ++L G Sbjct: 880 VFDLDQGEESPEGTSKPVVPAELINHADREGWTAAHIAASKGFKNCLEILCMHG 933
>Q9WV06:ANKR2_MOUSE Ankyrin repeat domain-containing protein 2 - Mus musculus (Mouse)| Length = 328 Score = 67.0 bits (162), Expect = 3e-10 Identities = 60/233 (25%), Positives = 98/233 (42%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA +G +++ L G + + +TAL +A GH E+++ L+ A + D L+ Sbjct: 124 AAVEGKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLD 183 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 TA+H+A GH +RL+ +D + D K+++ Sbjct: 184 C-TAMHWACRGGHLEVVRLL-------------------QSRGADTNVRD----KLLS-- 217 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA 1089 TPLH+A GHVE V+ L LG ++ E G + LH A Sbjct: 218 -----TPLHVAVRTGHVEIVEHFLSLGLDINAKDRE----------GDSALHDAVRLNRY 262 Query: 1090 VCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSP 1248 +LL+ GA++ AKN +G TP + W ++ + EP + L P Sbjct: 263 KIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERP 315 Score = 51.6 bits (122), Expect = 1e-05 Identities = 31/89 (34%), Positives = 48/89 (53%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 R + LH A+ +GH EI+ LLE+G ++ ++ TA+ AC+ GH EVV+ L A+ Sbjct: 150 RRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADT 209 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLA 795 + D L T +H A GH + L+ Sbjct: 210 NVRDKLL-STPLHVAVRTGHVEIVEHFLS 237 Score = 44.7 bits (104), Expect = 0.002 Identities = 26/84 (30%), Positives = 44/84 (52%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 +H+A GH E+V LL G + N+R+ T L A + GH E+V+ + +I+ D Sbjct: 187 MHWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKD 246 Query: 721 YLNGGTAIHFAALHGHARCLRLVL 792 G +A+H A + ++L+L Sbjct: 247 -REGDSALHDAVRLNRYKIIKLLL 269 Score = 44.7 bits (104), Expect = 0.002 Identities = 20/59 (33%), Positives = 36/59 (61%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 ++PLH A GH EIV L G++IN ++ G +AL A + +++++ L+L A++ Sbjct: 217 STPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGADM 275
>O75762:TRPA1_HUMAN Transient receptor potential cation channel subfamily A member 1 -| Homo sapiens (Human) Length = 1119 Score = 66.6 bits (161), Expect = 4e-10 Identities = 50/160 (31%), Positives = 83/160 (51%), Gaps = 10/160 (6%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA GH ++V LLL+ G + L ++ G TAL A G+ + ++ ++ + N+ Sbjct: 484 TPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVIL--DTNLKC 540 Query: 715 TDYL--NGGTAIHFAALHGHARCLRLVLADYVPSIPN-----FLNQTKHRSSEEVSDADF 873 TD L +G TA+HFAA GHA+ + L+L+ + N FL+ H +EV Sbjct: 541 TDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEVVLTII 600 Query: 874 DD---DGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 D +K+ + + G P+ + EC+++LLD Sbjct: 601 RSKRWDECLKIFSHNSPGNKCPI-TEMIEYLPECMKVLLD 639 Score = 65.9 bits (159), Expect = 7e-10 Identities = 70/277 (25%), Positives = 120/277 (43%), Gaps = 31/277 (11%) Frame = +1 Query: 493 NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESG-VEINLRNYRGQTALMQACQYGHW 669 NP L ++ +PLH A ++E++ +LLE +++NL G TA++ AC + Sbjct: 123 NPNLRNFNMM----APLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNS 178 Query: 670 EVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSS 849 E +Q L+ A +++ G IH AA G C+ ++L +H S Sbjct: 179 EALQILLNKGAKPCKSNKW-GCFPIHQAAFSGSKECMEIILRF----------GEEHGYS 227 Query: 850 EEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEV------- 1008 ++ +N+ +G TPLH+A NG +E +++ LD GA + V Sbjct: 228 RQLH------------INFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTA 275 Query: 1009 ---TIEDGTT-------------IDLL----GSGSTPLHYAACGGNAVCCQLLIARGANL 1128 G T +D++ G T LH A+ + LI+ GA++ Sbjct: 276 IHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDHHELADYLISVGADI 335 Query: 1129 AAKNASGSTPLMVA---HSWHRNSIEEILSNEPGGQI 1230 ++ G +PL++A SW N + +LS G Q+ Sbjct: 336 NKIDSEGRSPLILATASASW--NIVNLLLSK--GAQV 368 Score = 58.5 bits (140), Expect = 1e-07 Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 3/188 (1%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN- 621 A R G LL +N + +S + SPLH+AA+ G LL+ + L N Sbjct: 420 ACRQGGPGSVNNLLGFNVSI--HSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLLNE 477 Query: 622 --YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 G T L A + GH +VVQ L+L + +D+ NG TA+H A++ G+ + ++++L Sbjct: 478 GDLHGMTPLHLAAKNGHDKVVQ-LLLKKGALFLSDH-NGWTALHHASMGGYTQTMKVIL- 534 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 D +K + + G T LH AA GH + V L Sbjct: 535 ----------------------------DTNLKCTDRLDEDGNTALHFAAREGHAKAVAL 566 Query: 976 LLDLGASV 999 LL A + Sbjct: 567 LLSHNADI 574 Score = 58.2 bits (139), Expect = 1e-07 Identities = 76/316 (24%), Positives = 118/316 (37%), Gaps = 62/316 (19%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEIN-------------------LRNYR---------- 627 SPL A A IV+LLL G +++ L+N R Sbjct: 344 SPLILATASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIK 403 Query: 628 ---------GQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR-C 777 G T L AC+ G V L+ FN +IH + + +HFAA +G C Sbjct: 404 ELVMDEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSK-DKKSPLHFAASYGRINTC 462 Query: 778 LRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGH 957 RL+ +++SD ++G + G+TPLH+AA NGH Sbjct: 463 QRLL--------------------QDISDTRLLNEGDLH--------GMTPLHLAAKNGH 494 Query: 958 VECVQLLLDLGA---------------------SVSEVTIEDG--TTIDLLGSGSTPLHY 1068 + VQLLL GA +V ++ T L G+T LH+ Sbjct: 495 DKVVQLLLKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHF 554 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSP 1248 AA G+A LL++ A++ S + H+ + + I+ ++ + Sbjct: 555 AAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEVVLTIIRSKRWDE------- 607 Query: 1249 YLCLPLMSIMSIAREC 1296 CL + S S +C Sbjct: 608 --CLKIFSHNSPGNKC 621 Score = 53.9 bits (128), Expect = 3e-06 Identities = 66/269 (24%), Positives = 116/269 (43%), Gaps = 15/269 (5%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLES---GVEI-N 612 A ++GDL+ + L+ ++ GR + +H+AA QG EIV L++ S V+I N Sbjct: 246 AVQNGDLEMIKMCLDNGAQIDPVEK--GRCTAIHFAATQGATEIVKLMISSYSGSVDIVN 303 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 + +T L +A + H E+ L+ A+I++ D G + + A + L+L Sbjct: 304 TTDGCHETMLHRASLFDHHELADYLISVGADINKID-SEGRSPLILATASASWNIVNLLL 362 Query: 793 A-----DYVPSI-PNFLNQTKHR--SSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAAL 948 + D + NFL+ T + + + + ++V + + G TPLH A Sbjct: 363 SKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYACR 422 Query: 949 NGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANL 1128 G V LL S+ + + +PLH+AA G CQ L+ ++ Sbjct: 423 QGGPGSVNNLLGFNVSIHSKSKDK----------KSPLHFAASYGRINTCQRLLQDISDT 472 Query: 1129 AAKNAS---GSTPLMVAHSWHRNSIEEIL 1206 N G TPL +A + + ++L Sbjct: 473 RLLNEGDLHGMTPLHLAAKNGHDKVVQLL 501 Score = 36.2 bits (82), Expect = 0.57 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 25/134 (18%) Frame = +1 Query: 880 DGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGAS--------------------- 996 D +++++ D G TPLH A +E V+ LL GA+ Sbjct: 85 DSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNN 144 Query: 997 -VSEVTIEDGTT-IDLLG-SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL-M 1164 V +V +E T ++L G +G+T + A N+ Q+L+ +GA N G P+ Sbjct: 145 EVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLNKGAKPCKSNKWGCFPIHQ 204 Query: 1165 VAHSWHRNSIEEIL 1206 A S + +E IL Sbjct: 205 AAFSGSKECMEIIL 218 Score = 34.7 bits (78), Expect = 1.7 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Frame = +1 Query: 931 LHMAALNGHVECVQLLLDLGASVSEVTIEDGTTI--DLLGSGSTPLHYAACGGNAVCCQL 1104 LH AA G +E ++ ++T + + ++ G+TPLH A + Sbjct: 67 LHYAAAEGQIELME----------KITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKF 116 Query: 1105 LIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 L++RGAN +N + PL +A N + ++L Sbjct: 117 LLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVL 150 Score = 32.3 bits (72), Expect = 8.2 Identities = 26/82 (31%), Positives = 41/82 (50%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A+ G Q + +L+ N + G N+ LH+AA +GH + V+LLL +I L N Sbjct: 521 ASMGGYTQTMKVILDTNLKCTDRLDEDG-NTALHFAAREGHAKAVALLLSHNADIVL-NK 578 Query: 625 RGQTALMQACQYGHWEVVQTLM 690 + + L A EVV T++ Sbjct: 579 QQASFLHLALHNKRKEVVLTII 600
>Q9JIA3:IKBB_RAT NF-kappa-B inhibitor beta - Rattus norvegicus (Rat)| Length = 359 Score = 66.6 bits (161), Expect = 4e-10 Identities = 79/272 (29%), Positives = 111/272 (40%), Gaps = 22/272 (8%) Frame = +1 Query: 412 GCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL 591 G + G + G + E L + P + Y T G ++ LH A H + LL Sbjct: 20 GLGSLGPDAAAPGGPGLVAELSPELSWAPLVFGYVTEDG-DTALHLAVIHQHEPFLDFLL 78 Query: 592 --ESGVE-INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALH 762 +G E ++L+N GQTAL A G V+ L A + T+ G TA+H A Sbjct: 79 GFSAGTEYLDLQNDLGQTALHLAAILGEASTVEKLYAAGAGVLVTER-GGHTALHLAC-R 136 Query: 763 GHARCLRLVLADYVPSIPNFLNQTKHRSSEE----VSDADF---------------DDDG 885 A VL PS P + T S++ S A D+D Sbjct: 137 VRAHTCAYVLLQPRPSHPRDASDTYLTQSQDHTPDTSHAPVATDPQPNPGNEEELRDEDW 196 Query: 886 LVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLH 1065 +++ DG TPLH+A ++ E VQLL D GA +++ G TPLH Sbjct: 197 RLQLEAENYDGH-TPLHVAVIHKDAEMVQLLRDAGADLNKPEPT---------CGRTPLH 246 Query: 1066 YAACGGNAVCCQLLIARGANLAAKNASGSTPL 1161 A G A LL+ GA+ A+ G TPL Sbjct: 247 LAVEGQAAGVLALLLKAGADPTARMYGGRTPL 278
>Q862Z2:ASB5_RABIT Ankyrin repeat and SOCS box protein 5 - Oryctolagus cuniculus| (Rabbit) Length = 329 Score = 66.6 bits (161), Expect = 4e-10 Identities = 65/235 (27%), Positives = 98/235 (41%), Gaps = 11/235 (4%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA+QG + LL G +N T L +AC H +TL+ AN++ Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTIDHITPLHEACLGDHVACARTLLEAGANVNA 131 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVL-----ADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 ++G T + A G C L+L A +P+ ++ + E D Sbjct: 132 IT-IDGVTPLFNACSQGSTSCTELLLEYGAKAQLESCLPSPTHEAASKGHHEFLDL---- 186 Query: 880 DGLVKMVNWKADGGL------TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +++W D TPL++A ++ C+ LL GA V + D Sbjct: 187 -----LISWGIDVDQDIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWD------- 234 Query: 1042 GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 TPLH AA + LLI GA++ AKN P+ VA + + +E IL Sbjct: 235 ----TPLHAAAQQSSTEIVNLLIEFGADINAKNTELLRPVDVATT--SSMVERIL 283 Score = 55.8 bits (133), Expect = 7e-07 Identities = 41/131 (31%), Positives = 61/131 (46%), Gaps = 1/131 (0%) Frame = +1 Query: 922 LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQ 1101 +TPLH A L HV C + LL+ GA+V+ +TI+ G TPL A G+ C + Sbjct: 104 ITPLHEACLGDHVACARTLLEAGANVNAITID----------GVTPLFNACSQGSTSCTE 153 Query: 1102 LLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPYLCLPL-MSIM 1278 LL+ GA ++ S A H ++ ++S G P+L PL ++ M Sbjct: 154 LLLEYGAKAQLESCLPSPTHEAASKGHHEFLDLLIS---WGIDVDQDIPHLGTPLYVACM 210 Query: 1279 SIARECGWRYL 1311 S C W+ L Sbjct: 211 SQQFHCIWKLL 221 Score = 35.4 bits (80), Expect = 0.97 Identities = 16/30 (53%), Positives = 22/30 (73%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 ++PLH AA Q EIV+LL+E G +IN +N Sbjct: 234 DTPLHAAAQQSSTEIVNLLIEFGADINAKN 263
>Q92625:ANKS1_HUMAN Ankyrin repeat and SAM domain-containing protein 1A - Homo sapiens| (Human) Length = 1134 Score = 66.6 bits (161), Expect = 4e-10 Identities = 63/206 (30%), Positives = 92/206 (44%), Gaps = 1/206 (0%) Frame = +1 Query: 388 LSLVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRN-SPLHYAAAQG 564 L+ V +S GC L AA GD Q R L+ P R + N + LH AA G Sbjct: 105 LTNVADSKGCYP----LHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYG 160 Query: 565 HHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAI 744 H E+V +LLE + +RN + +T L A YG EVV+ L+ + N+ + T + Sbjct: 161 HTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCN-TKKHTPL 219 Query: 745 HFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGL 924 H AA +GH ++++L DA D N++ + G Sbjct: 220 HLAARNGHKAVVQVLL-----------------------DAGMDS-------NYQTEMG- 248 Query: 925 TPLHMAALNGHVECVQLLLDLGASVS 1002 + LH AAL G + VQ+LL G V+ Sbjct: 249 SALHEAALFGKTDVVQILLAAGTDVN 274 Score = 61.2 bits (147), Expect = 2e-08 Identities = 56/208 (26%), Positives = 93/208 (44%), Gaps = 2/208 (0%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH+AA GH ++V +LL + N+ + +G L A G ++V+ L+ + R Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141 Query: 715 TDYLNGG--TAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + N TA+H AA +GH ++++L EE++D Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLL-------------------EELTDPT------ 176 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 M N K + TPL +AAL G +E V++LL+ ++ + TPLH Sbjct: 177 --MRNNKFE---TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKK----------HTPLHL 221 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGS 1152 AA G+ Q+L+ G + + GS Sbjct: 222 AARNGHKAVVQVLLDAGMDSNYQTEMGS 249 Score = 53.9 bits (128), Expect = 3e-06 Identities = 68/269 (25%), Positives = 110/269 (40%), Gaps = 10/269 (3%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQG--------HHEIVSL 585 + L+ AAR G L LL + + GG S + G H + SL Sbjct: 5 QELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHPLSSL 64 Query: 586 L-LESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALH 762 L + G +N + G T L A GH +VV+ L+ +A + D G +H AA Sbjct: 65 LSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADS-KGCYPLHLAAWK 123 Query: 763 GHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMA 942 G A+ +RL++ + R +E+ +D + T LH A Sbjct: 124 GDAQIVRLLIHQ---------GPSHTRVNEQNNDNE------------------TALHCA 156 Query: 943 ALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGA 1122 A GH E V++LL+ +++ T+ + TPL AA G ++L+ Sbjct: 157 AQYGHTEVVKVLLE---ELTDPTMRNNKF-------ETPLDLAALYGRLEVVKMLLNAHP 206 Query: 1123 NLAAKNASGSTPL-MVAHSWHRNSIEEIL 1206 NL + N TPL + A + H+ ++ +L Sbjct: 207 NLLSCNTKKHTPLHLAARNGHKAVVQVLL 235 Score = 46.6 bits (109), Expect = 4e-04 Identities = 36/109 (33%), Positives = 48/109 (44%), Gaps = 3/109 (2%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 VN G TPLH AALNGH + V++LL D T G PLH AA Sbjct: 73 VNCVDSTGYTPLHHAALNGHKDVVEVLLR----------NDALTNVADSKGCYPLHLAAW 122 Query: 1078 GGNAVCCQLLIARG---ANLAAKNASGSTPLMVAHSWHRNSIEEILSNE 1215 G+A +LLI +G + +N T L A + + ++L E Sbjct: 123 KGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEE 171
>Q9BZF9:UACA_HUMAN Uveal autoantigen with coiled-coil domains and ankyrin repeats - Homo| sapiens (Human) Length = 1416 Score = 66.2 bits (160), Expect = 5e-10 Identities = 60/223 (26%), Positives = 97/223 (43%), Gaps = 2/223 (0%) Frame = +1 Query: 550 AAAQGHHE-IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYL 726 AA +G E + S+L + GV + G++ G+ E + +++ +I +D Sbjct: 41 AAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTA 100 Query: 727 NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNW 906 G A+H AA +GHA CL+ +L P T+H + Sbjct: 101 -GRNALHLAAKYGHALCLQKLLQYNCP--------TEHADLQ------------------ 133 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 G T LH AA+ +QLL D GASV+ ++ G TPL A Sbjct: 134 ----GRTALHDAAMADCPSSIQLLCDHGASVNAKDVD----------GRTPLVLATQMSR 179 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLMVAHSWH-RNSIEEILSN 1212 CQLLI RGA++ +++ T LM+ + R+++E ++ N Sbjct: 180 PTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKN 222 Score = 63.2 bits (152), Expect = 4e-09 Identities = 73/274 (26%), Positives = 108/274 (39%), Gaps = 23/274 (8%) Frame = +1 Query: 373 ASMGFLSLVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYA 552 AS G + ++ + +RL+ AA GD+++ ++L GR S H Sbjct: 17 ASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVNPGKLDVEGR-SVFHVV 75 Query: 553 AAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNG 732 ++G+ E ++ +L GV+I + G+ AL A +YGH +Q L+ +N D L G Sbjct: 76 TSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHAD-LQG 134 Query: 733 GTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKA 912 TA+H AA +AD SI + H +S D D Sbjct: 135 RTALHDAA-----------MADCPSSIQLLCD---HGASVNAKDVD-------------- 166 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVS----------------------EVTIEDGT 1026 G TPL +A QLL+D GA V+ EV I++G Sbjct: 167 --GRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGA 224 Query: 1027 TIDLLGS-GSTPLHYAACGGNAVCCQLLIARGAN 1125 I LL + G +YA G N LL N Sbjct: 225 DISLLDALGHDSSYYARIGDNLDILTLLKTASEN 258
>Q06547:GABP2_HUMAN GA-binding protein beta chain - Homo sapiens (Human)| Length = 395 Score = 66.2 bits (160), Expect = 5e-10 Identities = 41/122 (33%), Positives = 63/122 (51%) Frame = +1 Query: 427 GERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE 606 G++L+ AAR G E R L+ A ++T SPLH AA GH+ +LL +GV Sbjct: 7 GKKLLEAARAGQDDEVRILMANG---APFTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVS 63 Query: 607 INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRL 786 + R +T L A GH +V+ L+ A+++ D L TA+H+A H H + L Sbjct: 64 RDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLK-MTALHWATEHNHQEVVEL 122 Query: 787 VL 792 ++ Sbjct: 123 LI 124 Score = 55.1 bits (131), Expect = 1e-06 Identities = 24/59 (40%), Positives = 40/59 (67%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 +PLH AA++GH IV +LL+ G ++N ++ TAL A ++ H EVV+ L+ + A++H Sbjct: 73 TPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131 Score = 48.5 bits (114), Expect = 1e-04 Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = +1 Query: 853 EVSDADFDDDGLVKMVN---WKADG-GLTPLHMAALNGHVECVQLLLDLGASVSEVTIED 1020 E + A DD+ + M N + D G +PLH+AA GH ++LL G S T D Sbjct: 12 EAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVD 71 Query: 1021 GTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEE 1200 TPLH AA G+A ++L+ GA++ AK+ T L A + + E Sbjct: 72 ----------RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVE 121 Query: 1201 IL 1206 +L Sbjct: 122 LL 123 Score = 46.2 bits (108), Expect = 6e-04 Identities = 54/201 (26%), Positives = 82/201 (40%) Frame = +1 Query: 640 LMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPN 819 L++A + G + V+ LM N TD+L G + +H AA +GH Sbjct: 10 LLEAARAGQDDEVRILMA-NGAPFTTDWL-GTSPLHLAAQYGH----------------- 50 Query: 820 FLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASV 999 + ++E + A D K+ TPLHMAA GH V++LL GA V Sbjct: 51 ------YSTTEVLLRAGVSRDARTKVDR-------TPLHMAASEGHASIVEVLLKHGADV 97 Query: 1000 SEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW 1179 + D+L T LH+A + +LLI GA++ ++ T ++ Sbjct: 98 N--------AKDML--KMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDN 147 Query: 1180 HRNSIEEILSNEPGGQIRTLP 1242 + EIL QI T P Sbjct: 148 GNEDLAEILQIAMQNQINTNP 168
>Q91ZT7:ASB10_MOUSE Ankyrin repeat and SOCS box protein 10 - Mus musculus (Mouse)| Length = 467 Score = 66.2 bits (160), Expect = 5e-10 Identities = 76/281 (27%), Positives = 112/281 (39%), Gaps = 45/281 (16%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA++GH E++ LLL + + G+TAL +AC GH V+ L++ A+ + Sbjct: 118 TPLHVAASRGHTEVLELLLRRRAKPDSAP-GGRTALHEACSAGHAACVRVLLVAGADPNT 176 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 D +G +H G C+ L+L F Q R+ +E Sbjct: 177 LDQ-DGKRPLHLCRGPGILECVELLL--------KFGAQVDGRTEDEEE----------- 216 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTI-------------- 1032 TPLH+AA GHVE LLL GA E T + Sbjct: 217 ----------TPLHIAARLGHVELADLLLRWGACPDVRNSEGWTPLLAACDIRCQSPKDA 266 Query: 1033 ------------DLLGSGS----------TPLHYAACGGNAVCCQLLIARGANLAAKNAS 1146 LL G+ PLH A G++ QLL++ G N A + Sbjct: 267 EATTNRCFQLCRLLLSVGADADAANQDKQRPLHLACRHGHSAVVQLLLSCGVNANAMDYG 326 Query: 1147 GSTPL---------MVAHSWHRNSIEEILSNEPGGQIRTLP 1242 G TPL VAHS +++ ++L++ G +R P Sbjct: 327 GHTPLHCALLGPTTAVAHS-PEHTVRDLLNH---GAVRVWP 363 Score = 56.6 bits (135), Expect = 4e-07 Identities = 62/228 (27%), Positives = 88/228 (38%), Gaps = 16/228 (7%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G + LL R A+ + G + LH A + GH V +LL +G + N + Sbjct: 123 AASRGHTEVLELLLR---RRAKPDSAPGGRTALHEACSAGHAACVRVLLVAGADPNTLDQ 179 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA-DY 801 G+ L G E V+ L+ F A + T +H AA GH L+L Sbjct: 180 DGKRPLHLCRGPGILECVELLLKFGAQVDGRTEDEEETPLHIAARLGHVELADLLLRWGA 239 Query: 802 VPSIPNFLNQT-----------KHRSSEEVSDADFDDDGLVKMVNWKADGG----LTPLH 936 P + N T + +E ++ F L+ V AD PLH Sbjct: 240 CPDVRNSEGWTPLLAACDIRCQSPKDAEATTNRCFQLCRLLLSVGADADAANQDKQRPLH 299 Query: 937 MAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACG 1080 +A +GH VQLLL G + + + G TPLH A G Sbjct: 300 LACRHGHSAVVQLLLSCGVNANAMDY----------GGHTPLHCALLG 337
>Q8N283:ANR35_HUMAN Ankyrin repeat domain-containing protein 35 - Homo sapiens (Human)| Length = 1001 Score = 66.2 bits (160), Expect = 5e-10 Identities = 76/279 (27%), Positives = 118/279 (42%), Gaps = 4/279 (1%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 ++L+ A GD+ AL G+ SP H AA++G E +++LL +G +I Sbjct: 22 QKLLEAVHRGDVGRVAALASRKSARPTKLDSNGQ-SPFHLAASKGLTECLTILLANGADI 80 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 N +N G TAL A + V+ L+ AN D N + +H+AA G A + L+ Sbjct: 81 NSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAEN-RSPLHWAASSGCASSV-LL 138 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 L D H + +V D D G TPL +A+L GH Sbjct: 139 LCD-------------HEAFLDVLDND----------------GRTPLMIASLGGHAAIC 169 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 LL GA V+ D + + L A G+A +LL++ GA+ A +++G Sbjct: 170 SQLLQRGARVNVTDKNDKSALIL----------ACEKGSAEVAELLLSHGADAGAVDSTG 219 Query: 1150 STPLMVA-HSWHR---NSIEEILSNEPGGQIRTLPSPYL 1254 L A H+ + +++ LS G R + P L Sbjct: 220 HDALHYALHTQDKALWRHLQQALSRRRRGGQRLVQHPDL 258
>Q05823:RN5A_HUMAN 2-5A-dependent ribonuclease - Homo sapiens (Human)| Length = 741 Score = 65.9 bits (159), Expect = 7e-10 Identities = 74/279 (26%), Positives = 121/279 (43%), Gaps = 13/279 (4%) Frame = +1 Query: 418 SASGER--------LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHE 573 S+SG R L+ A ++ D+ + LLE + GG +PLH A + Sbjct: 15 SSSGRRAAVEDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGW-TPLHNAVQMSRED 73 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 IV LLL G + LR G T + A G ++++ + A+++ D+ G TA A Sbjct: 74 IVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFY-GFTAFMEA 132 Query: 754 ALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPL 933 A++G + L+ + N R ++E D + L K GG T L Sbjct: 133 AVYGKVKALKFL-------YKRGANVNLRRKTKE------DQERLRK-------GGATAL 172 Query: 934 HMAALNGHVECVQLLLD-LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA---VCCQ 1101 AA GHVE +++LLD +GA V+ D +G + +H ++ Sbjct: 173 MDAAEKGHVEVLKILLDEMGADVN--------ACDNMGRNAL-IHALLSSDDSDVEAITH 223 Query: 1102 LLIARGANLAAKNASGSTPLMVA-HSWHRNSIEEILSNE 1215 LL+ GA++ + G TPL++A H ++ +L E Sbjct: 224 LLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQE 262 Score = 52.8 bits (125), Expect = 6e-06 Identities = 50/186 (26%), Positives = 82/186 (44%), Gaps = 17/186 (9%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH- 711 +P AA G +++ L L G ++N ++ G TA M+A YG + ++ L AN++ Sbjct: 94 TPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNL 153 Query: 712 ----RTDY----LNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEE-VSD 864 + D G TA+ AA GH L+++L + + N ++ +S Sbjct: 154 RRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSS 213 Query: 865 ADFDDDGLVKM-------VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDG 1023 D D + + + VN + + G TPL +A H+ VQ LL+ T DG Sbjct: 214 DDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDG 273 Query: 1024 TTIDLL 1041 T LL Sbjct: 274 KTALLL 279
>Q8R516:MIB2_MOUSE E3 ubiquitin-protein ligase MIB2 - Mus musculus (Mouse)| Length = 973 Score = 65.9 bits (159), Expect = 7e-10 Identities = 103/444 (23%), Positives = 162/444 (36%), Gaps = 42/444 (9%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G ++ R LL+ + G N+ LHY A E +LL +G ++ RN Sbjct: 488 AAYLGQVELVRLLLQARASMDLPDDEG--NTVLHYTAMGNQPEATRVLLSAGCAVDARNG 545 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 TAL A Q G EVV+ L +++ D + T +H A G + + V Sbjct: 546 TRSTALHVAVQRGFLEVVKILCERGCDVNLPD-AHADTPLHSAISAGAGASSIVEVLTEV 604 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLV---------KMVNWKADGGLTPLHMAALNGH 957 P I + T + + A L ++V+ K + G T LH+AALN H Sbjct: 605 PGID--VTATNSQGFTLLHHASLKGHVLAVRKILARARQLVDAKKEDGFTALHLAALNNH 662 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 E Q+L+ G +V + + +PLH A + LL+ G ++ + Sbjct: 663 REVAQVLIREGR--CDVNVRNRKL-------QSPLHLAVQQAHLGLVPLLVDAGCSVNTE 713 Query: 1138 NASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPYLCLPLMSIMSIARECGWRYLNK 1317 + G T L VA R+ + ++++ GG P P L + + C + Sbjct: 714 DEEGDTALHVA--LQRHQLLPLVADRAGGD----PGPLQLLSRLQASGLP-GCTELTVGA 766 Query: 1318 SPVCI----------------DPCAVCLDGSCSVAAEGCKHEFCTRCA----------LY 1419 + C P + +G A +GC F R A + Sbjct: 767 AVACFLALEGADVSYANHRGRSPLDLATEGRVLKALQGCAQRFRERQAGGGGGVPPGPRH 826 Query: 1420 LCSTSYTSAN-----PAG--AIPCPLCRHPIISFVALPGTSPKRELPRNSLSLSFCATCP 1578 + ST T N AG A C +C + + P + + + C C Sbjct: 827 VLSTPNTVTNLHVSGTAGPEAAECLVCSELALLILFSP-CQHRTVCEECARRMKKCIRCQ 885 Query: 1579 AVSSDSAAPGGTEFHCGSGVRMPP 1650 V S P G+E V PP Sbjct: 886 VVISKKLRPDGSEVVNAIQVPGPP 909
>Q91ZT9:ASB8_MOUSE Ankyrin repeat and SOCS box protein 8 - Mus musculus (Mouse)| Length = 288 Score = 65.9 bits (159), Expect = 7e-10 Identities = 52/172 (30%), Positives = 77/172 (44%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN 705 G PLH A + V LLLE G E+N + +TAL A + V+ L+ + AN Sbjct: 52 GTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAERDE-ACVEVLLEYGAN 110 Query: 706 IHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG 885 + D N T +H+AA +A C+R +L S V+ D+++D Sbjct: 111 PNALDG-NRDTPLHWAAFKNNAECVRALL----------------ESGASVNALDYNND- 152 Query: 886 LVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 TPL AA+ G++E V +LLD GA V + ++ T I L Sbjct: 153 -------------TPLSWAAMKGNLESVSILLDYGAEVRVINLKGQTPISRL 191 Score = 57.4 bits (137), Expect = 2e-07 Identities = 55/198 (27%), Positives = 83/198 (41%) Frame = +1 Query: 568 HEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIH 747 H+ V L+ G ++N + L AC + V+ L+ A ++ D N TA+H Sbjct: 34 HDNVEDLIRGGADVNC-THGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNR-TALH 91 Query: 748 FAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLT 927 +AA A C+ VL +Y + PN L+ + T Sbjct: 92 YAAERDEA-CVE-VLLEYGAN-PNALDGNRD----------------------------T 120 Query: 928 PLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLL 1107 PLH AA + ECV+ LL+ GASV+ + + TPL +AA GN +L Sbjct: 121 PLHWAAFKNNAECVRALLESGASVNALDYNN----------DTPLSWAAMKGNLESVSIL 170 Query: 1108 IARGANLAAKNASGSTPL 1161 + GA + N G TP+ Sbjct: 171 LDYGAEVRVINLKGQTPI 188 Score = 55.8 bits (133), Expect = 7e-07 Identities = 44/143 (30%), Positives = 66/143 (46%), Gaps = 32/143 (22%) Frame = +1 Query: 829 QTKHRSSEEV-----SDADFDDDGLVKMVNWKAD-----GGLTPLHMAALNGHVECVQLL 978 Q+K+ SE + + F D + ++ AD G L PLH A + +CV+LL Sbjct: 13 QSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELL 72 Query: 979 LDLGASVS---------------------EVTIEDGTTIDLL-GSGSTPLHYAACGGNAV 1092 L+ GA V+ EV +E G + L G+ TPLH+AA NA Sbjct: 73 LEKGAEVNALDGYNRTALHYAAERDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAE 132 Query: 1093 CCQLLIARGANLAAKNASGSTPL 1161 C + L+ GA++ A + + TPL Sbjct: 133 CVRALLESGASVNALDYNNDTPL 155 Score = 50.8 bits (120), Expect = 2e-05 Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Frame = +1 Query: 448 ARDGDLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 A + D LLEY NP + G R++PLH+AA + + E V LLESG +N + Sbjct: 93 AAERDEACVEVLLEYGANPN----ALDGNRDTPLHWAAFKNNAECVRALLESGASVNALD 148 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAI 744 Y T L A G+ E V L+ + A + R L G T I Sbjct: 149 YNNDTPLSWAAMKGNLESVSILLDYGAEV-RVINLKGQTPI 188
>Q08E43:ASB8_BOVIN Ankyrin repeat and SOCS box protein 8 - Bos taurus (Bovine)| Length = 288 Score = 65.9 bits (159), Expect = 7e-10 Identities = 52/172 (30%), Positives = 77/172 (44%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN 705 G PLH A + V LLLE G E+N + +TAL A + V+ L+ + AN Sbjct: 52 GTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDE-ACVEVLLEYGAN 110 Query: 706 IHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG 885 + D N T +H+AA +A C+R +L S V+ D+++D Sbjct: 111 PNALDG-NRDTPLHWAAFKNNAECVRALL----------------ESGASVNALDYNND- 152 Query: 886 LVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 TPL AA+ G++E V +LLD GA V + ++ T I L Sbjct: 153 -------------TPLSWAAMKGNLESVSILLDYGAEVRVINLKGQTPISRL 191 Score = 57.0 bits (136), Expect = 3e-07 Identities = 55/198 (27%), Positives = 83/198 (41%) Frame = +1 Query: 568 HEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIH 747 H+ V L+ G ++N + L AC + V+ L+ A ++ D N TA+H Sbjct: 34 HDNVEDLIRGGADVNC-THGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNR-TALH 91 Query: 748 FAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLT 927 +AA A C+ VL +Y + PN L+ + T Sbjct: 92 YAAEKDEA-CVE-VLLEYGAN-PNALDGNRD----------------------------T 120 Query: 928 PLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLL 1107 PLH AA + ECV+ LL+ GASV+ + + TPL +AA GN +L Sbjct: 121 PLHWAAFKNNAECVRALLESGASVNALDYNN----------DTPLSWAAMKGNLESVSIL 170 Query: 1108 IARGANLAAKNASGSTPL 1161 + GA + N G TP+ Sbjct: 171 LDYGAEVRVINLKGQTPI 188 Score = 55.8 bits (133), Expect = 7e-07 Identities = 44/143 (30%), Positives = 66/143 (46%), Gaps = 32/143 (22%) Frame = +1 Query: 829 QTKHRSSEEV-----SDADFDDDGLVKMVNWKAD-----GGLTPLHMAALNGHVECVQLL 978 Q+K+ SE + + F D + ++ AD G L PLH A + +CV+LL Sbjct: 13 QSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELL 72 Query: 979 LDLGASVS---------------------EVTIEDGTTIDLL-GSGSTPLHYAACGGNAV 1092 L+ GA V+ EV +E G + L G+ TPLH+AA NA Sbjct: 73 LEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAE 132 Query: 1093 CCQLLIARGANLAAKNASGSTPL 1161 C + L+ GA++ A + + TPL Sbjct: 133 CVRALLESGASVNALDYNNDTPL 155 Score = 50.8 bits (120), Expect = 2e-05 Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Frame = +1 Query: 448 ARDGDLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 A + D LLEY NP + G R++PLH+AA + + E V LLESG +N + Sbjct: 93 AAEKDEACVEVLLEYGANPN----ALDGNRDTPLHWAAFKNNAECVRALLESGASVNALD 148 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAI 744 Y T L A G+ E V L+ + A + R L G T I Sbjct: 149 YNNDTPLSWAAMKGNLESVSILLDYGAEV-RVINLKGQTPI 188
>Q6P6B7:ANR16_HUMAN Ankyrin repeat domain-containing protein 16 - Homo sapiens (Human)| Length = 361 Score = 65.5 bits (158), Expect = 9e-10 Identities = 64/226 (28%), Positives = 94/226 (41%), Gaps = 1/226 (0%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLE-SGVEINLRN 621 A+R+GD + LL P + + R +PLH AA GH E V +LL+ E + R+ Sbjct: 144 ASREGDPLILQYLLTVCPGAWKTES-KIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRD 202 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADY 801 G TALM A Q GH +V + L+ + + G A+H AA+ G +R + Sbjct: 203 NCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFL---- 258 Query: 802 VPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLL 981 VS+ D D + LT LH AA GH +Q LL Sbjct: 259 ------------------VSELGVDVDVRATSTH------LTALHYAAKEGHTSTIQTLL 294 Query: 982 DLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG 1119 LGA ++ ++ + LH A G + C + L+ G Sbjct: 295 SLGADINSKDEKN----------RSALHLACAGQHLACAKFLLQSG 330 Score = 60.5 bits (145), Expect = 3e-08 Identities = 63/253 (24%), Positives = 102/253 (40%), Gaps = 42/253 (16%) Frame = +1 Query: 538 PLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN---- 705 PLH AA+ GH + V LL G ++ T LM AC + V+Q L+ AN Sbjct: 74 PLHEAASMGHRDCVRYLLGRGAAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLK 133 Query: 706 -----------------------------IHRTDYLNGGTAIHFAALHGHARCLRLVL-- 792 +T+ T +H AA+HGH ++++L Sbjct: 134 NKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKR 193 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDAD-----FDDDGLVKMVNWKADGGLTPLHMAALNGH 957 Y P + T + + D D+ G ++ + G LH AA+ G Sbjct: 194 CQYEPDYRDNCGVTALMDAIQCGHIDVARLLLDEHG--ACLSAEDSLGAQALHRAAVTGQ 251 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGS--TPLHYAACGGNAVCCQLLIARGANLA 1131 E ++ L VSE+ G +D+ + + T LHYAA G+ Q L++ GA++ Sbjct: 252 DEAIRFL------VSEL----GVDVDVRATSTHLTALHYAAKEGHTSTIQTLLSLGADIN 301 Query: 1132 AKNASGSTPLMVA 1170 +K+ + L +A Sbjct: 302 SKDEKNRSALHLA 314 Score = 38.5 bits (88), Expect = 0.11 Identities = 28/84 (33%), Positives = 38/84 (45%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 G T LH AA +GH + + L + E T D PLH AA G+ C Sbjct: 37 GDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDY---------KRPLHEAASMGHRDCV 87 Query: 1099 QLLIARGANLAAKNASGSTPLMVA 1170 + L+ RGA + + TPLM+A Sbjct: 88 RYLLGRGAAVDCLKKADWTPLMMA 111
>Q96AX9:MIB2_HUMAN E3 ubiquitin-protein ligase MIB2 - Homo sapiens (Human)| Length = 1013 Score = 65.1 bits (157), Expect = 1e-09 Identities = 62/227 (27%), Positives = 96/227 (42%), Gaps = 9/227 (3%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 N+ LHYAA E +LL +G + N TAL A Q G EVV+ L +++ Sbjct: 557 NTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 616 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 D + T +H A G + + VP+I + T + + A L Sbjct: 617 LPD-AHSDTPLHSAISAGTGASGIVEVLTEVPNID--VTATNSQGFTLLHHASLKGHALA 673 Query: 892 ---------KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLG 1044 ++V+ K + G T LH+AALN H E Q+L+ G +V + + Sbjct: 674 VRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGR--CDVNVRNRKL----- 726 Query: 1045 SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHR 1185 +PLH A + LL+ G ++ A++ G T L VA H+ Sbjct: 727 --QSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQ 771 Score = 45.4 bits (106), Expect = 0.001 Identities = 40/121 (33%), Positives = 55/121 (45%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 G T L +AA G VE ++LLL A V E G+T LHYAA G Sbjct: 523 GRTALQVAAYLGQVELIRLLLQARAGVDLPDDE----------GNTALHYAALGNQPEAT 572 Query: 1099 QLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPYLCLPLMSIM 1278 ++L++ G A N++ ST L VA R +E + + G LP + PL S + Sbjct: 573 RVLLSAGCRADAINSTQSTALHVA--VQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI 630 Query: 1279 S 1281 S Sbjct: 631 S 631
>Q00420:GABP2_MOUSE GA-binding protein beta chain - Mus musculus (Mouse)| Length = 383 Score = 65.1 bits (157), Expect = 1e-09 Identities = 41/122 (33%), Positives = 62/122 (50%) Frame = +1 Query: 427 GERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE 606 G++L+ AAR G E R L+ A ++T SPLH AA GH +LL +GV Sbjct: 7 GKKLLEAARAGQDDEVRILMANG---APFTTDWLGTSPLHLAAQYGHFSTTEVLLRAGVS 63 Query: 607 INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRL 786 + R +T L A GH +V+ L+ A+++ D L TA+H+A H H + L Sbjct: 64 RDARTKVDRTPLHMAASEGHANIVEVLLKHGADVNAKDMLK-MTALHWATEHNHQEVVEL 122 Query: 787 VL 792 ++ Sbjct: 123 LI 124 Score = 55.1 bits (131), Expect = 1e-06 Identities = 24/59 (40%), Positives = 40/59 (67%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 +PLH AA++GH IV +LL+ G ++N ++ TAL A ++ H EVV+ L+ + A++H Sbjct: 73 TPLHMAASEGHANIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131 Score = 48.1 bits (113), Expect = 1e-04 Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = +1 Query: 853 EVSDADFDDDGLVKMVN---WKADG-GLTPLHMAALNGHVECVQLLLDLGASVSEVTIED 1020 E + A DD+ + M N + D G +PLH+AA GH ++LL G S T D Sbjct: 12 EAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHFSTTEVLLRAGVSRDARTKVD 71 Query: 1021 GTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEE 1200 TPLH AA G+A ++L+ GA++ AK+ T L A + + E Sbjct: 72 ----------RTPLHMAASEGHANIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVE 121 Query: 1201 IL 1206 +L Sbjct: 122 LL 123 Score = 45.8 bits (107), Expect = 7e-04 Identities = 54/201 (26%), Positives = 81/201 (40%) Frame = +1 Query: 640 LMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPN 819 L++A + G + V+ LM N TD+L G + +H AA +GH ++L Sbjct: 10 LLEAARAGQDDEVRILMA-NGAPFTTDWL-GTSPLHLAAQYGHFSTTEVLLRA------- 60 Query: 820 FLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASV 999 G+ + K D TPLHMAA GH V++LL GA V Sbjct: 61 ---------------------GVSRDARTKVDR--TPLHMAASEGHANIVEVLLKHGADV 97 Query: 1000 SEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW 1179 + D+L T LH+A + +LLI GA++ ++ T ++ Sbjct: 98 N--------AKDML--KMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDN 147 Query: 1180 HRNSIEEILSNEPGGQIRTLP 1242 + EIL QI T P Sbjct: 148 GNEDLAEILQIAMQNQINTNP 168
>Q8HYY4:UACA_BOVIN Uveal autoantigen with coiled-coil domains and ankyrin repeats| protein - Bos taurus (Bovine) Length = 1401 Score = 64.7 bits (156), Expect = 1e-09 Identities = 61/223 (27%), Positives = 98/223 (43%), Gaps = 2/223 (0%) Frame = +1 Query: 550 AAAQGHHEIVS-LLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYL 726 AA +G E VS +L + GV + G++A G+ E + +++ +I +D Sbjct: 28 AAERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITTSDTA 87 Query: 727 NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNW 906 G A+H AA +GHA CL+ +L P T+H + Sbjct: 88 -GRNALHLAAKYGHALCLQKLLQYNCP--------TEHVDLQ------------------ 120 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 G T LH AA+ +QLL D GASV+ ++ G TPL A Sbjct: 121 ----GRTALHDAAMADCPSSIQLLCDHGASVNAKDVD----------GRTPLVLATQMCR 166 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLMVAHSWH-RNSIEEILSN 1212 CQLLI RGA++ +++ T LM+ + ++++E ++ N Sbjct: 167 PTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLIKN 209 Score = 61.6 bits (148), Expect = 1e-08 Identities = 69/255 (27%), Positives = 102/255 (40%), Gaps = 23/255 (9%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 +RL+ AA GD+++ ++L GR S H A++G+ E ++ +L GV+I Sbjct: 23 DRLMRAAERGDVEKVSSILAKKGVNPGKLDVEGR-SAFHVVASKGNLECLNAILIHGVDI 81 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 + G+ AL A +YGH +Q L+ +N D L G TA+H AA Sbjct: 82 TTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHVD-LQGRTALHDAA----------- 129 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 +AD SI + H +S D D G TPL +A Sbjct: 130 MADCPSSIQLLCD---HGASVNAKDVD----------------GRTPLVLATQMCRPTIC 170 Query: 970 QLLLDLGASVS----------------------EVTIEDGTTIDLLGS-GSTPLHYAACG 1080 QLL+D GA ++ EV I++G + LL + G +YA G Sbjct: 171 QLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLIKNGADVTLLDALGHDSSYYARIG 230 Query: 1081 GNAVCCQLLIARGAN 1125 N LL N Sbjct: 231 DNLDILTLLKTASEN 245
>Q00653:NFKB2_HUMAN Nuclear factor NF-kappa-B p100 subunit - Homo sapiens (Human)| Length = 900 Score = 64.7 bits (156), Expect = 1e-09 Identities = 75/269 (27%), Positives = 109/269 (40%), Gaps = 34/269 (12%) Frame = +1 Query: 457 GDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL-------ESGVEINL 615 G +ARALL L G ++PLH A G ++ ++ + GV +NL Sbjct: 465 GVTADARALLAGQRHLLTAQDENG-DTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNL 522 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA--ALHGHARCLRLV 789 N+ QT L A G VV L+ A+ D +G +A+H A A G LR + Sbjct: 523 TNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDR-HGDSAMHLALRAGAGAPELLRAL 581 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 L P++P L+ DF+ GL P+H+A EC+ Sbjct: 582 LQSGAPAVPQLLHMP-----------DFE--------------GLYPVHLAVRARSPECL 616 Query: 970 QLLLDLGASVSEVTIEDG-------TTIDLLG------------------SGSTPLHYAA 1074 LL+D GA V + G T ++ LG +G+TPLH AA Sbjct: 617 DLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAA 676 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL 1161 G +LL+ GA++ A+N PL Sbjct: 677 GLGYPTLTRLLLKAGADIHAENEEPLCPL 705
>Q9TU71:ANKR1_RABIT Ankyrin repeat domain-containing protein 1 - Oryctolagus cuniculus| (Rabbit) Length = 319 Score = 64.7 bits (156), Expect = 1e-09 Identities = 55/187 (29%), Positives = 81/187 (43%) Frame = +1 Query: 631 QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPS 810 +TAL +AC GH +V+ LM A I D L TAIH+A G+ L+L+L Sbjct: 154 RTALHRACLEGHLAIVEKLMEAGAQIEFRDMLES-TAIHWACRGGNLEVLKLLL------ 206 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 ++S D K+++ T LH+A GH EC + L+ Sbjct: 207 ----------NKGAKISARD-------KLLS-------TALHVAVRTGHYECAEHLIACE 242 Query: 991 ASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 A ++ E G TPLH A +LLI GA+L KN++G TP+ + Sbjct: 243 ADLNAKDRE----------GDTPLHDAVRLNRYKMIRLLIMYGADLTIKNSAGKTPMDLV 292 Query: 1171 HSWHRNS 1191 +W + Sbjct: 293 LNWQNGT 299 Score = 58.9 bits (141), Expect = 8e-08 Identities = 49/171 (28%), Positives = 75/171 (43%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + + LH A +GH IV L+E+G +I R+ TA+ AC+ G+ EV++ L+ A I Sbjct: 153 KRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNLEVLKLLLNKGAKI 212 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 D L TA+H A GH C ++A +AD Sbjct: 213 SARDKLL-STALHVAVRTGHYECAEHLIA---------------------CEAD------ 244 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +N K G TPLH A + ++LL+ GA ++ T +DL+ Sbjct: 245 ---LNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLTIKNSAGKTPMDLV 292 Score = 48.1 bits (113), Expect = 1e-04 Identities = 32/110 (29%), Positives = 56/110 (50%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 L EA A +E+ L ++ +H+A G+ E++ LLL G +I+ R+ TAL Sbjct: 172 LMEAGAQIEFRDML--------ESTAIHWACRGGNLEVLKLLLNKGAKISARDKLLSTAL 223 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 A + GH+E + L+ A+++ D G T +H A + +RL++ Sbjct: 224 HVAVRTGHYECAEHLIACEADLNAKD-REGDTPLHDAVRLNRYKMIRLLI 272 Score = 47.8 bits (112), Expect = 2e-04 Identities = 33/98 (33%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 T LH A L GH+ V+ L++ GA + D+L S T +H+A GGN +L Sbjct: 155 TALHRACLEGHLAIVEKLMEAGAQIE--------FRDMLES--TAIHWACRGGNLEVLKL 204 Query: 1105 LIARGANLAAKNASGSTPLMVA-HSWHRNSIEEILSNE 1215 L+ +GA ++A++ ST L VA + H E +++ E Sbjct: 205 LLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACE 242
>O60733:PA2G6_HUMAN 85 kDa calcium-independent phospholipase A2 - Homo sapiens (Human)| Length = 806 Score = 64.3 bits (155), Expect = 2e-09 Identities = 71/262 (27%), Positives = 105/262 (40%), Gaps = 6/262 (2%) Frame = +1 Query: 403 NSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVS 582 N GC+ L A R GD + L++Y + + G + HYA + +++ Sbjct: 149 NEEGCTP----LHLACRKGDGEILVELVQYCHTQMDVTDYKGE-TVFHYAVQGDNSQVLQ 203 Query: 583 LLLESGVE-INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAAL 759 LL + V +N N +G T L ACQ G E+V+ L+L NA + G IH A Sbjct: 204 LLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNARCNIMG--PNGYPIHSAMK 261 Query: 760 HGHARCLRLVLADYVPSI----PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLT 927 C ++++ I P + H + G VN + G T Sbjct: 262 FSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAKNAEMARMLLKRGC--NVNSTSSAGNT 319 Query: 928 PLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS-GSTPLHYAACGGNAVCCQL 1104 LH+A + +C +LL GA+ D G G+TPLH A N + Sbjct: 320 ALHVAVMRNRFDCAIVLLTHGANA-----------DARGEHGNTPLHLAMSKDNVEMIKA 368 Query: 1105 LIARGANLAAKNASGSTPLMVA 1170 LI GA + N G TP +A Sbjct: 369 LIVFGAEVDTPNDFGETPTFLA 390 Score = 35.8 bits (81), Expect = 0.74 Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 1/97 (1%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 G TPLH+A G E + L+ + +VT G T+ HYA G N+ Sbjct: 152 GCTPLHLACRKGDGEILVELVQYCHTQMDVTDYKGETV---------FHYAVQGDNSQVL 202 Query: 1099 QLLIARG-ANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 QLL A L N G TPL +A + + +L Sbjct: 203 QLLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVL 239
>Q8BG95:MYPT2_MOUSE Protein phosphatase 1 regulatory subunit 12B - Mus musculus (Mouse)| Length = 976 Score = 64.3 bits (155), Expect = 2e-09 Identities = 69/242 (28%), Positives = 102/242 (42%), Gaps = 35/242 (14%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 A + G + V LL G +IN N G TAL QAC + ++V+ L+ AN+++ D N Sbjct: 65 ACSSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQD--N 122 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPS-------------IPN-----------FLNQTK 837 G + LH A C L +A+Y S +P+ L Q K Sbjct: 123 EG----WTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVK 178 Query: 838 HRSSE-EVSDADFDDDGLVKMVNW----------KADGGLTPLHMAALNGHVECVQLLLD 984 + + E S + + L W +A G T LH+AA G+ E ++LL+ Sbjct: 179 KQGVDLEQSRKEEEQQMLQDARQWLNSGRIEDVRQARSGATALHVAAAKGYSEVLRLLIQ 238 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 G E+ ++D G TPLH AA G C +L ++ +N G TP Sbjct: 239 AGY---ELNVQDH-------DGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFD 288 Query: 1165 VA 1170 VA Sbjct: 289 VA 290 Score = 41.6 bits (96), Expect = 0.014 Identities = 25/75 (33%), Positives = 42/75 (56%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 LQ+AR L + R+ + LH AAA+G+ E++ LL+++G E+N++++ G T L Sbjct: 196 LQDARQWLN-SGRIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPL 254 Query: 643 MQACQYGHWEVVQTL 687 A +G E L Sbjct: 255 HAAAHWGVKEACSIL 269
>P81069:GABP3_MOUSE GA-binding protein beta-2-1 chain - Mus musculus (Mouse)| Length = 414 Score = 64.3 bits (155), Expect = 2e-09 Identities = 42/122 (34%), Positives = 63/122 (51%) Frame = +1 Query: 427 GERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE 606 G+RL+ AAR G E R L+ A ++T SPLH AA GH+ +LL +GV Sbjct: 7 GKRLLEAARKGQDDEVRILMANG---APFTTDWLGTSPLHLAAQYGHYSTAEVLLRAGVS 63 Query: 607 INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRL 786 + R +T L A GH +V+ L+ A+++ D L TA+H+A H H + L Sbjct: 64 RDARTKVDRTPLHMAAADGHVHIVELLVRSGADVNAKDMLQ-MTALHWATEHHHRLVVEL 122 Query: 787 VL 792 ++ Sbjct: 123 LI 124 Score = 50.4 bits (119), Expect = 3e-05 Identities = 31/89 (34%), Positives = 49/89 (55%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA+ G A LL ++R + +PLH AAA GH IV LL+ SG ++N ++ Sbjct: 45 AAQYGHYSTAEVLLRAG--VSRDARTKVDRTPLHMAAADGHVHIVELLVRSGADVNAKDM 102 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIH 711 TAL A ++ H VV+ L+ + A+++ Sbjct: 103 LQMTALHWATEHHHRLVVELLIKYGADVY 131 Score = 46.6 bits (109), Expect = 4e-04 Identities = 53/199 (26%), Positives = 84/199 (42%) Frame = +1 Query: 640 LMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPN 819 L++A + G + V+ LM N TD+L G + +H AA +GH Sbjct: 10 LLEAARKGQDDEVRILMA-NGAPFTTDWL-GTSPLHLAAQYGH----------------- 50 Query: 820 FLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASV 999 + ++E + A D K+ TPLHMAA +GHV V+LL+ GA V Sbjct: 51 ------YSTAEVLLRAGVSRDARTKVDR-------TPLHMAAADGHVHIVELLVRSGADV 97 Query: 1000 SEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSW 1179 + D+L T LH+A + + +LLI GA++ A + + +A Sbjct: 98 N--------AKDML--QMTALHWATEHHHRLVVELLIKYGADVYAFSKFDKSAFDIAMEK 147 Query: 1180 HRNSIEEILSNEPGGQIRT 1236 + I +L Q+ T Sbjct: 148 NNTEILVMLQEAMQNQVNT 166
>Q5R6D7:ASB8_PONPY Ankyrin repeat and SOCS box protein 8 - Pongo pygmaeus (Orangutan)| Length = 288 Score = 64.3 bits (155), Expect = 2e-09 Identities = 52/172 (30%), Positives = 76/172 (44%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN 705 G PLH A + V LLLE G E+N + +TAL A + V+ L+ + AN Sbjct: 52 GTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDE-ACVEVLLEYGAN 110 Query: 706 IHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG 885 + D N T +H+AA +A C+R +L S V+ D+++D Sbjct: 111 PNALDG-NRDTPLHWAAFKNNAECVRALL----------------ESGASVNALDYNND- 152 Query: 886 LVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 TPL AA+ G++E V +LLD GA V + + T I L Sbjct: 153 -------------TPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPISRL 191 Score = 56.2 bits (134), Expect = 5e-07 Identities = 55/198 (27%), Positives = 83/198 (41%) Frame = +1 Query: 568 HEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIH 747 H+ V L+ G ++N + L AC + V+ L+ A ++ D N TA+H Sbjct: 34 HDNVEDLIRGGADVNC-THGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNR-TALH 91 Query: 748 FAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLT 927 +AA A C+ VL +Y + PN L+ + T Sbjct: 92 YAAEKDEA-CVE-VLLEYGAN-PNALDGNRD----------------------------T 120 Query: 928 PLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLL 1107 PLH AA + ECV+ LL+ GASV+ + + TPL +AA GN +L Sbjct: 121 PLHWAAFKNNAECVRALLESGASVNALDYNN----------DTPLSWAAMKGNLESVSIL 170 Query: 1108 IARGANLAAKNASGSTPL 1161 + GA + N G TP+ Sbjct: 171 LDYGAEVRVINLIGQTPI 188 Score = 55.8 bits (133), Expect = 7e-07 Identities = 44/143 (30%), Positives = 66/143 (46%), Gaps = 32/143 (22%) Frame = +1 Query: 829 QTKHRSSEEV-----SDADFDDDGLVKMVNWKAD-----GGLTPLHMAALNGHVECVQLL 978 Q+K+ SE + + F D + ++ AD G L PLH A + +CV+LL Sbjct: 13 QSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELL 72 Query: 979 LDLGASVS---------------------EVTIEDGTTIDLL-GSGSTPLHYAACGGNAV 1092 L+ GA V+ EV +E G + L G+ TPLH+AA NA Sbjct: 73 LEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAE 132 Query: 1093 CCQLLIARGANLAAKNASGSTPL 1161 C + L+ GA++ A + + TPL Sbjct: 133 CVRALLESGASVNALDYNNDTPL 155 Score = 49.7 bits (117), Expect = 5e-05 Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Frame = +1 Query: 448 ARDGDLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 A + D LLEY NP + G R++PLH+AA + + E V LLESG +N + Sbjct: 93 AAEKDEACVEVLLEYGANPN----ALDGNRDTPLHWAAFKNNAECVRALLESGASVNALD 148 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAI 744 Y T L A G+ E V L+ + A + R L G T I Sbjct: 149 YNNDTPLSWAAMKGNLESVSILLDYGAEV-RVINLIGQTPI 188
>Q9H765:ASB8_HUMAN Ankyrin repeat and SOCS box protein 8 - Homo sapiens (Human)| Length = 288 Score = 64.3 bits (155), Expect = 2e-09 Identities = 52/172 (30%), Positives = 76/172 (44%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN 705 G PLH A + V LLLE G E+N + +TAL A + V+ L+ + AN Sbjct: 52 GTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDE-ACVEVLLEYGAN 110 Query: 706 IHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG 885 + D N T +H+AA +A C+R +L S V+ D+++D Sbjct: 111 PNALDG-NRDTPLHWAAFKNNAECVRALL----------------ESGASVNALDYNND- 152 Query: 886 LVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 TPL AA+ G++E V +LLD GA V + + T I L Sbjct: 153 -------------TPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPISRL 191 Score = 56.2 bits (134), Expect = 5e-07 Identities = 55/198 (27%), Positives = 83/198 (41%) Frame = +1 Query: 568 HEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIH 747 H+ V L+ G ++N + L AC + V+ L+ A ++ D N TA+H Sbjct: 34 HDNVEDLIRGGADVNC-THGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNR-TALH 91 Query: 748 FAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLT 927 +AA A C+ VL +Y + PN L+ + T Sbjct: 92 YAAEKDEA-CVE-VLLEYGAN-PNALDGNRD----------------------------T 120 Query: 928 PLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLL 1107 PLH AA + ECV+ LL+ GASV+ + + TPL +AA GN +L Sbjct: 121 PLHWAAFKNNAECVRALLESGASVNALDYNN----------DTPLSWAAMKGNLESVSIL 170 Query: 1108 IARGANLAAKNASGSTPL 1161 + GA + N G TP+ Sbjct: 171 LDYGAEVRVINLIGQTPI 188 Score = 55.8 bits (133), Expect = 7e-07 Identities = 44/143 (30%), Positives = 66/143 (46%), Gaps = 32/143 (22%) Frame = +1 Query: 829 QTKHRSSEEV-----SDADFDDDGLVKMVNWKAD-----GGLTPLHMAALNGHVECVQLL 978 Q+K+ SE + + F D + ++ AD G L PLH A + +CV+LL Sbjct: 13 QSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELL 72 Query: 979 LDLGASVS---------------------EVTIEDGTTIDLL-GSGSTPLHYAACGGNAV 1092 L+ GA V+ EV +E G + L G+ TPLH+AA NA Sbjct: 73 LEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAE 132 Query: 1093 CCQLLIARGANLAAKNASGSTPL 1161 C + L+ GA++ A + + TPL Sbjct: 133 CVRALLESGASVNALDYNNDTPL 155 Score = 49.7 bits (117), Expect = 5e-05 Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Frame = +1 Query: 448 ARDGDLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 A + D LLEY NP + G R++PLH+AA + + E V LLESG +N + Sbjct: 93 AAEKDEACVEVLLEYGANPN----ALDGNRDTPLHWAAFKNNAECVRALLESGASVNALD 148 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAI 744 Y T L A G+ E V L+ + A + R L G T I Sbjct: 149 YNNDTPLSWAAMKGNLESVSILLDYGAEV-RVINLIGQTPI 188
>Q9D1A4:ASB5_MOUSE Ankyrin repeat and SOCS box protein 5 - Mus musculus (Mouse)| Length = 329 Score = 64.3 bits (155), Expect = 2e-09 Identities = 65/235 (27%), Positives = 97/235 (41%), Gaps = 11/235 (4%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 SPLH AA+QG + LL G +N T L +AC H +TL+ AN + Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTIDHVTPLHEACLGDHVACARTLLEAGANANA 131 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVL-----ADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 ++G T + A G A C L+L A P+ ++ + E D Sbjct: 132 IT-IDGVTPLFNACSQGSASCAELLLEYGAKAQLESCFPSPTHEAASKGHHECLDI---- 186 Query: 880 DGLVKMVNWKADGGL------TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 ++ W D TPL++A ++ C+ LL GA V + D Sbjct: 187 -----LIAWGIDVDQDIPHLGTPLYVACMSQQFHCIWKLLYAGADVHKGKYWD------- 234 Query: 1042 GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 TPLH AA + LL+ GA++ AKN P+ +A S +++E IL Sbjct: 235 ----TPLHAAAQQPSTEIVNLLLEFGADINAKNTDLLRPVDLATS--NSAVERIL 283 Score = 55.1 bits (131), Expect = 1e-06 Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 1/131 (0%) Frame = +1 Query: 922 LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQ 1101 +TPLH A L HV C + LL+ GA+ + +TI+ G TPL A G+A C + Sbjct: 104 VTPLHEACLGDHVACARTLLEAGANANAITID----------GVTPLFNACSQGSASCAE 153 Query: 1102 LLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPYLCLPL-MSIM 1278 LL+ GA ++ S A H ++ +++ G P+L PL ++ M Sbjct: 154 LLLEYGAKAQLESCFPSPTHEAASKGHHECLDILIA---WGIDVDQDIPHLGTPLYVACM 210 Query: 1279 SIARECGWRYL 1311 S C W+ L Sbjct: 211 SQQFHCIWKLL 221 Score = 35.4 bits (80), Expect = 0.97 Identities = 17/30 (56%), Positives = 22/30 (73%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 ++PLH AA Q EIV+LLLE G +IN +N Sbjct: 234 DTPLHAAAQQPSTEIVNLLLEFGADINAKN 263
>Q5BKI6:ANKR1_XENTR Ankyrin repeat domain-containing protein 1 - Xenopus tropicalis| (Western clawed frog) (Silurana tropicalis) Length = 318 Score = 64.3 bits (155), Expect = 2e-09 Identities = 58/220 (26%), Positives = 91/220 (41%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA ++ L G + N + +TAL +AC GH ++V+ L+ ANI D L Sbjct: 126 AALDNKMPVIEKYLADGGDPNTCDEYKRTALHRACSEGHTDMVEKLIEAGANIEFKDMLE 185 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 TA+H+ G L+L+L ++ D K+++ Sbjct: 186 S-TALHWTCRGGSVETLKLLL----------------NKGAAINARD-------KLLS-- 219 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA 1089 TPLH+A GH EC + L+ A + E G TP+H Sbjct: 220 -----TPLHVAVRTGHYECAEHLIACEADLHARDRE----------GDTPMHDGVRLNRY 264 Query: 1090 VCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILS 1209 +LLI G +L KN++G TP+ + W +N +EI + Sbjct: 265 KMMRLLILYGVDLNIKNSAGKTPMELVMQW-QNGAKEIFN 303 Score = 49.7 bits (117), Expect = 5e-05 Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 8/108 (7%) Frame = +1 Query: 496 PRLARYSTFGG--------RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQA 651 P + +Y GG + + LH A ++GH ++V L+E+G I ++ TAL Sbjct: 133 PVIEKYLADGGDPNTCDEYKRTALHRACSEGHTDMVEKLIEAGANIEFKDMLESTALHWT 192 Query: 652 CQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 C+ G E ++ L+ A I+ D L T +H A GH C ++A Sbjct: 193 CRGGSVETLKLLLNKGAAINARDKLL-STPLHVAVRTGHYECAEHLIA 239 Score = 46.2 bits (108), Expect = 6e-04 Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 10/123 (8%) Frame = +1 Query: 877 DDGLVKMVNWKADGG---------LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTT 1029 D+ + + + ADGG T LH A GH + V+ L++ GA++ + + Sbjct: 129 DNKMPVIEKYLADGGDPNTCDEYKRTALHRACSEGHTDMVEKLIEAGANIEFKDMLE--- 185 Query: 1030 IDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA-HSWHRNSIEEIL 1206 ST LH+ GG+ +LL+ +GA + A++ STPL VA + H E ++ Sbjct: 186 -------STALHWTCRGGSVETLKLLLNKGAAINARDKLLSTPLHVAVRTGHYECAEHLI 238 Query: 1207 SNE 1215 + E Sbjct: 239 ACE 241 Score = 43.5 bits (101), Expect = 0.004 Identities = 32/110 (29%), Positives = 50/110 (45%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 L EA A +E+ L ++ LH+ G E + LLL G IN R+ T L Sbjct: 171 LIEAGANIEFKDML--------ESTALHWTCRGGSVETLKLLLNKGAAINARDKLLSTPL 222 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 A + GH+E + L+ A++H D G T +H + +RL++ Sbjct: 223 HVAVRTGHYECAEHLIACEADLHARD-REGDTPMHDGVRLNRYKMMRLLI 271 Score = 35.0 bits (79), Expect = 1.3 Identities = 13/60 (21%), Positives = 33/60 (55%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 ++PLH A GH+E L+ +++ R+ G T + + +++++ L+L+ +++ Sbjct: 219 STPLHVAVRTGHYECAEHLIACEADLHARDREGDTPMHDGVRLNRYKMMRLLILYGVDLN 278
>Q5UPG5:YL093_MIMIV Putative ankyrin repeat protein L93 - Mimivirus| Length = 421 Score = 63.9 bits (154), Expect = 3e-09 Identities = 60/216 (27%), Positives = 98/216 (45%), Gaps = 8/216 (3%) Frame = +1 Query: 547 YAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHW----EVVQTLMLFNANIHR 714 YA + + + LLL+ G + N+++ G TALM AC+Y + E+++ L+ A+I+ Sbjct: 224 YANTTSNIKTIKLLLDRGADTNIKDKIGLTALMLACKYANTPNSIEIIKLLLDKGADIN- 282 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 T G TA+ FA + + ++L+L D + D Sbjct: 283 TGNGEGWTALMFACKYANIEAIKLLL-----------------------DKNAD------ 313 Query: 895 MVNWKADGGLTPLHMAALNGH----VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 +N K GLT L +A + +E ++LLLD GA ++ G G T L Sbjct: 314 -INAKDKIGLTALMLACKYANTPNSIEIIKLLLDKGADINTGN----------GEGWTAL 362 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 +A N +LL+ + A++ AK+ G TPLM A Sbjct: 363 MFACKYANIEAIKLLLDKNADINAKDKDGWTPLMFA 398 Score = 59.7 bits (143), Expect = 5e-08 Identities = 51/170 (30%), Positives = 83/170 (48%), Gaps = 15/170 (8%) Frame = +1 Query: 547 YAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYL 726 YA EI+ LLL+ G +IN N G TALM AC+Y + E ++ L+ NA+I+ D + Sbjct: 261 YANTPNSIEIIKLLLDKGADINTGNGEGWTALMFACKYANIEAIKLLLDKNADINAKDKI 320 Query: 727 NGGTAIHFAALHGHA----RCLRLVLADYVPSIPN--------FLNQTKHRSSEEVS--- 861 G TA+ A + + ++L+L D I + K+ + E + Sbjct: 321 -GLTALMLACKYANTPNSIEIIKLLL-DKGADINTGNGEGWTALMFACKYANIEAIKLLL 378 Query: 862 DADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVT 1011 D + D +N K G TPL A + ++E ++LLLD A ++E++ Sbjct: 379 DKNAD-------INAKDKDGWTPLMFACVYANIETIKLLLDKRADINEIS 421 Score = 57.8 bits (138), Expect = 2e-07 Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 2/133 (1%) Frame = +1 Query: 400 GNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPL--HYAAAQGHHE 573 GN G +A L+ A + +++ + LL+ N + G L YA E Sbjct: 284 GNGEGWTA----LMFACKYANIEAIKLLLDKNADINAKDKIGLTALMLACKYANTPNSIE 339 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA 753 I+ LLL+ G +IN N G TALM AC+Y + E ++ L+ NA+I+ D +G T + FA Sbjct: 340 IIKLLLDKGADINTGNGEGWTALMFACKYANIEAIKLLLDKNADINAKD-KDGWTPLMFA 398 Query: 754 ALHGHARCLRLVL 792 ++ + ++L+L Sbjct: 399 CVYANIETIKLLL 411 Score = 53.1 bits (126), Expect = 5e-06 Identities = 60/227 (26%), Positives = 104/227 (45%), Gaps = 7/227 (3%) Frame = +1 Query: 577 VSLLLESGVEINLRNYRGQTALMQAC----QYGHWEVVQTLMLFNANIHRTDYLNGGTAI 744 V+LLL G ++NL QT LM A Q G ++V+ L+ ++A I +D +G TA+ Sbjct: 86 VNLLLSKGAKVNLMKNEKQTVLMLASLNSRQIGSTDIVKLLLDYDAKIDISDE-DGWTAL 144 Query: 745 HFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGL 924 +A+++ + + + ++ LN+ DAD + K N + + Sbjct: 145 MYASINSNE-------SSTIATVKLLLNR----------DADIN-----KKDNQGKNSFM 182 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 + +++ V+LLL+ G+++ E+ T + + YA N +L Sbjct: 183 WACQYSNTTSNIKTVKLLLNRGSNIDELDNNGWTALMI------ACKYANTTSNIKTIKL 236 Query: 1105 LIARGANLAAKNASGSTPLMVAHSWHR--NSIEEI-LSNEPGGQIRT 1236 L+ RGA+ K+ G T LM+A + NSIE I L + G I T Sbjct: 237 LLDRGADTNIKDKIGLTALMLACKYANTPNSIEIIKLLLDKGADINT 283 Score = 53.1 bits (126), Expect = 5e-06 Identities = 73/275 (26%), Positives = 116/275 (42%), Gaps = 15/275 (5%) Frame = +1 Query: 457 GDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHE----IVSLLLESGVEINLRNY 624 G + LL+Y+ ++ G + L YA+ + V LLL +IN ++ Sbjct: 118 GSTDIVKLLLDYDAKIDISDEDGW--TALMYASINSNESSTIATVKLLLNRDADINKKDN 175 Query: 625 RGQTALMQACQYGHW----EVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 +G+ + M ACQY + + V+ L+ +NI D NG TA+ A + + Sbjct: 176 QGKNSFMWACQYSNTTSNIKTVKLLLNRGSNIDELDN-NGWTALMIACKYANT------- 227 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGH----V 960 + +I L++ AD N K GLT L +A + + Sbjct: 228 TSNIKTIKLLLDR----------GAD---------TNIKDKIGLTALMLACKYANTPNSI 268 Query: 961 ECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKN 1140 E ++LLLD GA ++ G G T L +A N +LL+ + A++ AK+ Sbjct: 269 EIIKLLLDKGADINTGN----------GEGWTALMFACKYANIEAIKLLLDKNADINAKD 318 Query: 1141 ASGSTPLMVAHSWHR--NSIEEI-LSNEPGGQIRT 1236 G T LM+A + NSIE I L + G I T Sbjct: 319 KIGLTALMLACKYANTPNSIEIIKLLLDKGADINT 353 Score = 36.6 bits (83), Expect = 0.44 Identities = 19/57 (33%), Positives = 32/57 (56%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 L +A + E + LLL+ +IN ++ G T LM AC Y + E ++ L+ A+I+ Sbjct: 362 LMFACKYANIEAIKLLLDKNADINAKDKDGWTPLMFACVYANIETIKLLLDKRADIN 418
>Q8WXI3:ASB10_HUMAN Ankyrin repeat and SOCS box protein 10 - Homo sapiens (Human)| Length = 467 Score = 63.9 bits (154), Expect = 3e-09 Identities = 69/248 (27%), Positives = 96/248 (38%), Gaps = 36/248 (14%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA++GH E++ LLL + G+TAL +AC GH V L++ A+ + Sbjct: 118 TPLHVAASRGHTEVLRLLLRRRARPDSAP-GGRTALHEACAAGHTACVHVLLVAGADPNI 176 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 D +G +H G C L+L F + RS EE Sbjct: 177 ADQ-DGKRPLHLCRGPGTLECAELLL--------RFGARVDGRSEEEEE----------- 216 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGA-------------------SVSEVTIE 1017 TPLH+AA GHVE LLL GA +T Sbjct: 217 ----------TPLHVAARLGHVELADLLLRRGACPDARNAEGWTPLLAACDVRCQSITDA 266 Query: 1018 DGTTID-------LLGSGS----------TPLHYAACGGNAVCCQLLIARGANLAAKNAS 1146 + TT LL +G+ PLH A G+A +LL++ G + + Sbjct: 267 EATTARCLQLCSLLLSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSANTMDYG 326 Query: 1147 GSTPLMVA 1170 G TPL A Sbjct: 327 GHTPLHCA 334 Score = 61.6 bits (148), Expect = 1e-08 Identities = 65/235 (27%), Positives = 93/235 (39%), Gaps = 16/235 (6%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA G + R LL R AR + G + LH A A GH V +LL +G + N+ + Sbjct: 123 AASRGHTEVLRLLLR---RRARPDSAPGGRTALHEACAAGHTACVHVLLVAGADPNIADQ 179 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA-DY 801 G+ L G E + L+ F A + T +H AA GH L+L Sbjct: 180 DGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLRRGA 239 Query: 802 VPSIPNFLNQTKHRSS-----EEVSDADFDDDGLVKMVNWKADGGLT----------PLH 936 P N T ++ + ++DA+ +++ + G PLH Sbjct: 240 CPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQRPLH 299 Query: 937 MAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQ 1101 +A GH V+LLL G S + T+D G TPLH A G A Q Sbjct: 300 LACRRGHAAVVELLLSCGVSAN--------TMDY--GGHTPLHCALQGPAAALAQ 344
>Q3UMR0:ANR27_MOUSE Ankyrin repeat domain-containing protein 27 - Mus musculus (Mouse)| Length = 1048 Score = 63.9 bits (154), Expect = 3e-09 Identities = 68/241 (28%), Positives = 92/241 (38%), Gaps = 39/241 (16%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNP-------------------------------RLARYS 516 E+L+ A DGDL+ R LLE+ +LAR S Sbjct: 671 EKLLRAVADGDLEMVRYLLEWTEDDLDDVEDAISTVDLEFCHPLCQCPKCAPAQKLARIS 730 Query: 517 TFG--------GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWE 672 G SPLH AA G ++V LLL+ G RN L ACQ GH++ Sbjct: 731 ANGLSVNVTNQDGFSPLHMAALHGRTDLVPLLLKHGAYSGARNTSQAVPLHLACQQGHFQ 790 Query: 673 VVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSE 852 V + L+ NA ++ D L+G T + A GH L+L +H +S Sbjct: 791 VAKCLLDSNAKPNKKD-LSGNTPLICACSAGHHEVAALLL--------------QHGAS- 834 Query: 853 EVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTI 1032 +N + G T LH A + H V+LLL GASV + T Sbjct: 835 ---------------INACNNKGNTALHEAVMGRHTLVVELLLFYGASVDILNKRQYTAA 879 Query: 1033 D 1035 D Sbjct: 880 D 880 Score = 55.8 bits (133), Expect = 7e-07 Identities = 67/287 (23%), Positives = 110/287 (38%), Gaps = 74/287 (25%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 ++PLH A +G + LLL +++ G T L AC YG + V+ L+ ++ Sbjct: 497 STPLHLACQKGFQSVTLLLLHYKASTEVQDNNGNTPLHLACTYGQEDCVKALVYYDVQAC 556 Query: 712 RTDYLN--GGTAIHFAALHGHARCLRLVLADYVP-SIPNFLNQT---------------- 834 R D N G TA+H AA G+ + +L + P ++ N L +T Sbjct: 557 RLDIGNEKGDTALHIAARWGYEGIIETLLQNGAPTAVQNRLKETPLKCALNSKILSIMEA 616 Query: 835 KHRSSE-EVSDADFDDDGLVKMVNWKADGGLT-----------------------PLHMA 942 H SS+ ++ + V+ + G T L A Sbjct: 617 HHLSSDRRPRPSEVPAQSPTRSVDSISQGSSTSSFSSISVSFRQEEVKKDYREVEKLLRA 676 Query: 943 ALNGHVECVQLLL--------DLGASVSEVTIE----------------------DGTTI 1032 +G +E V+ LL D+ ++S V +E +G ++ Sbjct: 677 VADGDLEMVRYLLEWTEDDLDDVEDAISTVDLEFCHPLCQCPKCAPAQKLARISANGLSV 736 Query: 1033 DLLG-SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 ++ G +PLH AA G LL+ GA A+N S + PL +A Sbjct: 737 NVTNQDGFSPLHMAALHGRTDLVPLLLKHGAYSGARNTSQAVPLHLA 783 Score = 55.1 bits (131), Expect = 1e-06 Identities = 28/86 (32%), Positives = 43/86 (50%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA G ++ L+ G +N +Y G T L ACQ G V L+ + A+ Sbjct: 465 TPLHVAALCGQASLIDFLVSKGAVVNATDYHGSTPLHLACQKGFQSVTLLLLHYKASTEV 524 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVL 792 D NG T +H A +G C++ ++ Sbjct: 525 QDN-NGNTPLHLACTYGQEDCVKALV 549 Score = 54.3 bits (129), Expect = 2e-06 Identities = 51/185 (27%), Positives = 73/185 (39%) Frame = +1 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 R+ RGQT L A G ++ L+ A ++ TDY +G T +H A G L+L Sbjct: 459 RDDRGQTPLHVAALCGQASLIDFLVSKGAVVNATDY-HGSTPLHLACQKGFQSVTLLLL- 516 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 +++S EV D + G TPLH+A G +CV+ Sbjct: 517 -------------HYKASTEVQD----------------NNGNTPLHLACTYGQEDCVKA 547 Query: 976 LLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGST 1155 L+ + I + G T LH AA G + L+ GA A +N T Sbjct: 548 LVYYDVQACRLDIGN-------EKGDTALHIAARWGYEGIIETLLQNGAPTAVQNRLKET 600 Query: 1156 PLMVA 1170 PL A Sbjct: 601 PLKCA 605 Score = 48.9 bits (115), Expect = 8e-05 Identities = 43/153 (28%), Positives = 58/153 (37%), Gaps = 29/153 (18%) Frame = +1 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL----------------- 1041 D G TPLH+AAL G + L+ GA V+ T + L Sbjct: 461 DRGQTPLHVAALCGQASLIDFLVSKGAVVNATDYHGSTPLHLACQKGFQSVTLLLLHYKA 520 Query: 1042 ------GSGSTPLHYAACGGNAVCCQLLI---ARGANLAAKNASGSTPLMVAHSW-HRNS 1191 +G+TPLH A G C + L+ + L N G T L +A W + Sbjct: 521 STEVQDNNGNTPLHLACTYGQEDCVKALVYYDVQACRLDIGNEKGDTALHIAARWGYEGI 580 Query: 1192 IEEILSN--EPGGQIRTLPSPYLCLPLMSIMSI 1284 IE +L N Q R +P C I+SI Sbjct: 581 IETLLQNGAPTAVQNRLKETPLKCALNSKILSI 613 Score = 47.0 bits (110), Expect = 3e-04 Identities = 59/227 (25%), Positives = 85/227 (37%), Gaps = 8/227 (3%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQA------CQYGHWEVVQTLMLFNANIH 711 A A G E+V LLE E +L + + + CQ Q L +AN Sbjct: 676 AVADGDLEMVRYLLE-WTEDDLDDVEDAISTVDLEFCHPLCQCPKCAPAQKLARISANGL 734 Query: 712 RTDYLN--GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG 885 + N G + +H AALHG D VP + L + + S A Sbjct: 735 SVNVTNQDGFSPLHMAALHGRT--------DLVPLL---LKHGAYSGARNTSQA------ 777 Query: 886 LVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLH 1065 PLH+A GH + + LLD A ++ + SG+TPL Sbjct: 778 -------------VPLHLACQQGHFQVAKCLLDSNAKPNKKDL----------SGNTPLI 814 Query: 1066 YAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 A G+ LL+ GA++ A N G+T L A + E+L Sbjct: 815 CACSAGHHEVAALLLQHGASINACNNKGNTALHEAVMGRHTLVVELL 861
>Q4KL97:ANKR1_XENLA Ankyrin repeat domain-containing protein 1 - Xenopus laevis (African| clawed frog) Length = 318 Score = 63.9 bits (154), Expect = 3e-09 Identities = 59/220 (26%), Positives = 90/220 (40%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA I+ L G + N + +TAL +AC GH +V+ L+ ANI D L Sbjct: 126 AALDNKMSIIEKYLADGGDPNTCDEYKRTALHRACSEGHTAIVEKLIEAGANIEFKDMLE 185 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 TA+H+ G L+L+L ++ D K+++ Sbjct: 186 S-TALHWTCRGGSVETLKLLL----------------NKGAAINARD-------KLLS-- 219 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA 1089 TPLH+A G+ EC + L+ A ++ E G TP+H Sbjct: 220 -----TPLHVAVRTGYYECGEHLIACEADLNAKDRE----------GDTPMHDGVRLNRY 264 Query: 1090 VCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILS 1209 +LLI G NL KN +G TP+ + W +N +EI + Sbjct: 265 KMIRLLILYGVNLNIKNCAGKTPMELVMQW-QNGAKEIFN 303 Score = 45.4 bits (106), Expect = 0.001 Identities = 27/83 (32%), Positives = 42/83 (50%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + + LH A ++GH IV L+E+G I ++ TAL C+ G E ++ L+ A I Sbjct: 152 KRTALHRACSEGHTAIVEKLIEAGANIEFKDMLESTALHWTCRGGSVETLKLLLNKGAAI 211 Query: 709 HRTDYLNGGTAIHFAALHGHARC 777 + D L T +H A G+ C Sbjct: 212 NARDKLL-STPLHVAVRTGYYEC 233 Score = 37.4 bits (85), Expect = 0.26 Identities = 30/110 (27%), Positives = 50/110 (45%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 L EA A +E+ L ++ LH+ G E + LLL G IN R+ T L Sbjct: 171 LIEAGANIEFKDML--------ESTALHWTCRGGSVETLKLLLNKGAAINARDKLLSTPL 222 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 A + G++E + L+ A+++ D G T +H + +RL++ Sbjct: 223 HVAVRTGYYECGEHLIACEADLNAKD-REGDTPMHDGVRLNRYKMIRLLI 271
>Q7ZT11:ANKR1_CHICK Ankyrin repeat domain-containing protein 1 - Gallus gallus (Chicken)| Length = 319 Score = 63.9 bits (154), Expect = 3e-09 Identities = 58/221 (26%), Positives = 91/221 (41%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA + ++ L + N+ N +TAL +AC GH EVV+ L+ A + D L Sbjct: 127 AALENKLPVIEKYLSDKGDPNVCNEYKRTALHRACSEGHLEVVKKLVEAGALLELKDMLE 186 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 TA+H+A G+ ++ +L D G+ + K Sbjct: 187 S-TALHWACRGGNLEIVKFLL----------------------------DKGINRNARDK 217 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA 1089 TPLH+A G +C + L+ A ++ E G TP+H A Sbjct: 218 LRS--TPLHVAVRTGQHDCAEHLIACEADLNAKDRE----------GDTPMHDAVRLNRY 265 Query: 1090 VCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSN 1212 +LLI GA+L KN G TP+ + W +N +E+ +N Sbjct: 266 KMVRLLILYGADLTIKNVDGKTPMDLVLQW-QNGTKELFNN 305 Score = 55.8 bits (133), Expect = 7e-07 Identities = 46/171 (26%), Positives = 77/171 (45%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + + LH A ++GH E+V L+E+G + L++ TAL AC+ G+ E+V+ L+ N Sbjct: 153 KRTALHRACSEGHLEVVKKLVEAGALLELKDMLESTALHWACRGGNLEIVKFLLDKGINR 212 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + D L T +H A G C ++A +AD Sbjct: 213 NARDKLR-STPLHVAVRTGQHDCAEHLIA---------------------CEAD------ 244 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +N K G TP+H A + V+LL+ GA ++ ++ T +DL+ Sbjct: 245 ---LNAKDREGDTPMHDAVRLNRYKMVRLLILYGADLTIKNVDGKTPMDLV 292 Score = 42.7 bits (99), Expect = 0.006 Identities = 33/110 (30%), Positives = 52/110 (47%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 L EA ALLE L ++ LH+A G+ EIV LL+ G+ N R+ T L Sbjct: 172 LVEAGALLELKDML--------ESTALHWACRGGNLEIVKFLLDKGINRNARDKLRSTPL 223 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 A + G + + L+ A+++ D G T +H A + +RL++ Sbjct: 224 HVAVRTGQHDCAEHLIACEADLNAKD-REGDTPMHDAVRLNRYKMVRLLI 272 Score = 42.4 bits (98), Expect = 0.008 Identities = 23/88 (26%), Positives = 47/88 (53%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A R G+L+ + LL+ + R + R++PLH A G H+ L+ ++N ++ Sbjct: 193 ACRGGNLEIVKFLLDKG--INRNARDKLRSTPLHVAVRTGQHDCAEHLIACEADLNAKDR 250 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANI 708 G T + A + +++V+ L+L+ A++ Sbjct: 251 EGDTPMHDAVRLNRYKMVRLLILYGADL 278
>Q3ZBX7:ANKR1_BOVIN Ankyrin repeat domain-containing protein 1 - Bos taurus (Bovine)| Length = 319 Score = 63.9 bits (154), Expect = 3e-09 Identities = 55/187 (29%), Positives = 80/187 (42%) Frame = +1 Query: 631 QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPS 810 +TAL +AC GH +V+ L+ A I D L TAIH+A+ G L+L+L Sbjct: 154 RTALHRACLEGHLAIVEKLIEAGAQIEFRDMLES-TAIHWASRGGSLDVLKLLL------ 206 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 ++S D K+++ TPLH+A GH EC + L+ Sbjct: 207 ----------NKGAKISARD-------KLLS-------TPLHVAVRTGHYECAEHLIACE 242 Query: 991 ASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 A ++ E G TPLH A +LLI GA+L KN +G TP+ + Sbjct: 243 ADLNAKDRE----------GDTPLHDAVRLNRYKMIRLLITYGADLNVKNCAGKTPMDLV 292 Query: 1171 HSWHRNS 1191 W + Sbjct: 293 LHWQNGT 299 Score = 52.8 bits (125), Expect = 6e-06 Identities = 46/171 (26%), Positives = 72/171 (42%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + + LH A +GH IV L+E+G +I R+ TA+ A + G +V++ L+ A I Sbjct: 153 KRTALHRACLEGHLAIVEKLIEAGAQIEFRDMLESTAIHWASRGGSLDVLKLLLNKGAKI 212 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 D L T +H A GH C ++A +AD Sbjct: 213 SARDKLL-STPLHVAVRTGHYECAEHLIA---------------------CEAD------ 244 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +N K G TPLH A + ++LL+ GA ++ T +DL+ Sbjct: 245 ---LNAKDREGDTPLHDAVRLNRYKMIRLLITYGADLNVKNCAGKTPMDLV 292 Score = 48.1 bits (113), Expect = 1e-04 Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 23/117 (19%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTID-------------LLGSG----- 1050 T LH A L GH+ V+ L++ GA + + + T I LL G Sbjct: 155 TALHRACLEGHLAIVEKLIEAGAQIEFRDMLESTAIHWASRGGSLDVLKLLLNKGAKISA 214 Query: 1051 -----STPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 STPLH A G+ C + LIA A+L AK+ G TPL A +R + +L Sbjct: 215 RDKLLSTPLHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLL 271 Score = 43.5 bits (101), Expect = 0.004 Identities = 30/110 (27%), Positives = 55/110 (50%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 L EA A +E+ L ++ +H+A+ G +++ LLL G +I+ R+ T L Sbjct: 172 LIEAGAQIEFRDML--------ESTAIHWASRGGSLDVLKLLLNKGAKISARDKLLSTPL 223 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 A + GH+E + L+ A+++ D G T +H A + +RL++ Sbjct: 224 HVAVRTGHYECAEHLIACEADLNAKD-REGDTPLHDAVRLNRYKMIRLLI 272 Score = 41.6 bits (96), Expect = 0.014 Identities = 21/89 (23%), Positives = 45/89 (50%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A+R G L + LL +++ ++PLH A GH+E L+ ++N ++ Sbjct: 193 ASRGGSLDVLKLLLNKGAKISARDKL--LSTPLHVAVRTGHYECAEHLIACEADLNAKDR 250 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIH 711 G T L A + +++++ L+ + A+++ Sbjct: 251 EGDTPLHDAVRLNRYKMIRLLITYGADLN 279 Score = 33.9 bits (76), Expect = 2.8 Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 9/110 (8%) Frame = +1 Query: 370 WASMG----FLSLVGNSFGCSASGERLVS-----AARDGDLQEARALLEYNPRLARYSTF 522 WAS G L L+ N ++ ++L+S A R G + A L+ L Sbjct: 192 WASRGGSLDVLKLLLNKGAKISARDKLLSTPLHVAVRTGHYECAEHLIACEADLNAKDRE 251 Query: 523 GGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWE 672 G ++PLH A ++++ LL+ G ++N++N G+T + HW+ Sbjct: 252 G--DTPLHDAVRLNRYKMIRLLITYGADLNVKNCAGKTPMDLVL---HWQ 296
>P83757:CACT_DROYA NF-kappa-B inhibitor cactus - Drosophila yakuba (Fruit fly)| Length = 489 Score = 63.5 bits (153), Expect = 3e-09 Identities = 69/296 (23%), Positives = 122/296 (41%), Gaps = 7/296 (2%) Frame = +1 Query: 385 FLSLVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQG 564 F S ++ + SG S+A + A ++ Y ++P H A G Sbjct: 179 FQSSTASTANANPSGXGATSSAPPSSINIXNAWEQF------YQQNDDGDTPXHLACISG 232 Query: 565 HHEIVSLLLESGVE---INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGG 735 E+V+ L+ +N++N QT L A +++ L+L A + +G Sbjct: 233 SVEVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPNIMRILLLAGAEVRDR---HGN 289 Query: 736 TAIHFAALHGHARCLRLVLADY-VPSIPNFLNQTKHRSSEE-VSDADFDDDGLVKMVNWK 909 TA+H + + G +C+R + ++ I Q HRS+++ VS F L + + Sbjct: 290 TALHLSCIAGEKQCVRALTEEFGATEIHEAHRQYGHRSNDKAVSSLSFAR--LPADLEIR 347 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA 1089 G +H+AA GH++ +++L+ GA ++ +G SG TPLH A G N Sbjct: 348 NYDGERCVHLAAEAGHIDILRILVSHGA---DINAREGK------SGRTPLHIAIEGCNE 398 Query: 1090 VCCQLLI--ARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPSPY 1251 L+ NL +G T A +++ ++ IL + S Y Sbjct: 399 DLANFLLDECEKLNLETATYAGLTAYQFACIMNKSRMQNILEKRGAETVTPPDSDY 454
>O60237:MYPT2_HUMAN Protein phosphatase 1 regulatory subunit 12B - Homo sapiens (Human)| Length = 982 Score = 63.2 bits (152), Expect = 4e-09 Identities = 68/237 (28%), Positives = 100/237 (42%), Gaps = 30/237 (12%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 A + G + V LL G +IN N G TAL QAC + ++V+ L+ AN+++ D Sbjct: 65 ACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN-E 123 Query: 730 GGTAIHFAALHG----------HARCLRLV---------LADYVPSIPNFLNQTKHRSSE 852 G T +H AA G H + +V LA+ L Q K + + Sbjct: 124 GWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVD 183 Query: 853 -EVSDADFDDDGLVKMVNW----------KADGGLTPLHMAALNGHVECVQLLLDLGASV 999 E S + + L W +A G T LH+AA G+ E ++LL+ G Sbjct: 184 LEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGY-- 241 Query: 1000 SEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 E+ ++D G TPLH AA G C +L ++ +N G TP VA Sbjct: 242 -ELNVQDY-------DGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVA 290 Score = 43.1 bits (100), Expect = 0.005 Identities = 20/49 (40%), Positives = 32/49 (65%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTL 687 LH AAA+G+ E++ LL+++G E+N+++Y G T L A +G E L Sbjct: 221 LHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSIL 269
>Q9CR42:ANKR1_MOUSE Ankyrin repeat domain-containing protein 1 - Mus musculus (Mouse)| Length = 319 Score = 63.2 bits (152), Expect = 4e-09 Identities = 55/183 (30%), Positives = 79/183 (43%) Frame = +1 Query: 631 QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPS 810 +TAL +AC GH +V+ LM A I D L TAIH+A G+A L+L+L Sbjct: 154 RTALHRACLEGHLAIVEKLMEAGAQIEFRDMLES-TAIHWACRGGNADVLKLLL------ 206 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 ++S D K+++ T LH+A GH EC + L+ Sbjct: 207 ----------NKGAKISARD-------KLLS-------TALHVAVRTGHYECAEHLIACE 242 Query: 991 ASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 A ++ E G TPLH A +LL+ GA+L KN +G TP+ + Sbjct: 243 ADLNAKDRE----------GDTPLHDAVRLNRYKMIRLLMTFGADLKVKNCAGKTPMDLV 292 Query: 1171 HSW 1179 W Sbjct: 293 LHW 295 Score = 58.9 bits (141), Expect = 8e-08 Identities = 48/171 (28%), Positives = 74/171 (43%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + + LH A +GH IV L+E+G +I R+ TA+ AC+ G+ +V++ L+ A I Sbjct: 153 KRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNADVLKLLLNKGAKI 212 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 D L TA+H A GH C ++A +AD Sbjct: 213 SARDKLL-STALHVAVRTGHYECAEHLIA---------------------CEAD------ 244 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +N K G TPLH A + ++LL+ GA + T +DL+ Sbjct: 245 ---LNAKDREGDTPLHDAVRLNRYKMIRLLMTFGADLKVKNCAGKTPMDLV 292 Score = 49.3 bits (116), Expect = 6e-05 Identities = 34/98 (34%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQL 1104 T LH A L GH+ V+ L++ GA + D+L S T +H+A GGNA +L Sbjct: 155 TALHRACLEGHLAIVEKLMEAGAQIE--------FRDMLES--TAIHWACRGGNADVLKL 204 Query: 1105 LIARGANLAAKNASGSTPLMVA-HSWHRNSIEEILSNE 1215 L+ +GA ++A++ ST L VA + H E +++ E Sbjct: 205 LLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACE 242 Score = 47.4 bits (111), Expect = 2e-04 Identities = 31/110 (28%), Positives = 56/110 (50%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 L EA A +E+ L ++ +H+A G+ +++ LLL G +I+ R+ TAL Sbjct: 172 LMEAGAQIEFRDML--------ESTAIHWACRGGNADVLKLLLNKGAKISARDKLLSTAL 223 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 A + GH+E + L+ A+++ D G T +H A + +RL++ Sbjct: 224 HVAVRTGHYECAEHLIACEADLNAKD-REGDTPLHDAVRLNRYKMIRLLM 272
>Q59H18:TNI3K_HUMAN Serine/threonine-protein kinase TNNI3K - Homo sapiens (Human)| Length = 936 Score = 62.8 bits (151), Expect = 6e-09 Identities = 64/198 (32%), Positives = 85/198 (42%), Gaps = 17/198 (8%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A + + E+++ LL SG +I Y G TAL A GH E L+ AN++ D Sbjct: 206 LHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQD 265 Query: 721 YLNGGTAIHFAALHGHARCLRLVL---AD------------YVPSIPNFLNQTKHRSSEE 855 + T +H AA +GH + RL+L AD ++ S FLN K EE Sbjct: 266 AV-FFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAK-LLMEE 323 Query: 856 VSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLL--DLGASVSEVTIEDGTT 1029 S AD VN + + PLH + GH + V+ LL DL V I Sbjct: 324 GSKAD---------VNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNI----- 369 Query: 1030 IDLLGSGSTPLHYAACGG 1083 G TPLH A G Sbjct: 370 -----YGDTPLHLACYNG 382 Score = 56.6 bits (135), Expect = 4e-07 Identities = 81/321 (25%), Positives = 129/321 (40%), Gaps = 63/321 (19%) Frame = +1 Query: 520 FGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 +GG + LH A GH E +LL+ G +N+++ T L A YGH +V + L+ F Sbjct: 233 YGGLTA-LHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 291 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 A+++ + + G +H A+ G +L++ + + N + H S F Sbjct: 292 ADVNVSGEV-GDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCS--RFGH 348 Query: 880 DGLVK------------MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIED- 1020 +VK +VN D TPLH+A NG E + ++ + + S +T E+ Sbjct: 349 HDIVKYLLQSDLEVQPHVVNIYGD---TPLHLACYNGKFEVAKEIIQISGTES-LTKENI 404 Query: 1021 ------------GTTIDLL---------------GSGSTPLHYAACGGNAVCCQLLIARG 1119 G +IDL+ G T LH A G+ Q L+ G Sbjct: 405 FSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNG 464 Query: 1120 A--NLAAKNASGS-------TPLMVAHSWHRNSIEEILS--------------NEPGGQI 1230 A NL A + S S T LM A+ ++I +L ++PGG Sbjct: 465 ADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLKHYKRPQDELPCNEYSQPGGDG 524 Query: 1231 RTLPSPYLCLPLMSIMSIARE 1293 + P PL I S+ +E Sbjct: 525 SYVSVP---SPLGKIKSMTKE 542
>P97819:PA2G6_MOUSE 85 kDa calcium-independent phospholipase A2 - Mus musculus (Mouse)| Length = 752 Score = 62.8 bits (151), Expect = 6e-09 Identities = 68/261 (26%), Positives = 104/261 (39%), Gaps = 5/261 (1%) Frame = +1 Query: 403 NSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVS 582 N GC+ L A R GD + L++Y + G + HYA + +++ Sbjct: 149 NEEGCTP----LHLACRKGDSEILVELVQYCHAQMDVTDNKGETA-FHYAVQGDNPQVLQ 203 Query: 583 LL-LESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAAL 759 LL + +N N +G T L AC+ G E+V+ L+L NA + GG IH A Sbjct: 204 LLGKNASAGLNQVNNQGLTPLHLACKMGKQEMVRVLLLCNARCNIMG--PGGFPIHTAMK 261 Query: 760 HGHARCLRLVLADYVPSI----PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLT 927 C ++++ I P + H + G V+ + G T Sbjct: 262 FSQKGCAEMIISMDSNQIHSKDPRYGASPLHWAKNAEMARMLLKRGCD--VDSTSSSGNT 319 Query: 928 PLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLL 1107 LH+A + +CV +LL GA+ G+TPLH A N + L Sbjct: 320 ALHVAVMRNRFDCVMVLLTYGANAGARGEH----------GNTPLHLAMSKDNMEMVKAL 369 Query: 1108 IARGANLAAKNASGSTPLMVA 1170 I GA + N G TP ++A Sbjct: 370 IVFGAEVDTPNDFGETPALIA 390
>Q4R544:ASB8_MACFA Ankyrin repeat and SOCS box protein 8 - Macaca fascicularis (Crab| eating macaque) (Cynomolgus monkey) Length = 288 Score = 62.8 bits (151), Expect = 6e-09 Identities = 51/172 (29%), Positives = 75/172 (43%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN 705 G PLH A + V LLLE G E+N + +T L A + V+ L+ + AN Sbjct: 52 GTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTVLHYAAEKDE-ACVEVLLEYGAN 110 Query: 706 IHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDG 885 + D N T +H+AA +A C+R +L S V+ D+++D Sbjct: 111 PNALDG-NRDTPLHWAAFKNNAECVRALL----------------ESGASVNALDYNND- 152 Query: 886 LVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 TPL AA+ G++E V +LLD GA V + + T I L Sbjct: 153 -------------TPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPISRL 191 Score = 55.8 bits (133), Expect = 7e-07 Identities = 44/143 (30%), Positives = 66/143 (46%), Gaps = 32/143 (22%) Frame = +1 Query: 829 QTKHRSSEEV-----SDADFDDDGLVKMVNWKAD-----GGLTPLHMAALNGHVECVQLL 978 Q+K+ SE + + F D + ++ AD G L PLH A + +CV+LL Sbjct: 13 QSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELL 72 Query: 979 LDLGASVS---------------------EVTIEDGTTIDLL-GSGSTPLHYAACGGNAV 1092 L+ GA V+ EV +E G + L G+ TPLH+AA NA Sbjct: 73 LEKGAEVNALDGYNRTVLHYAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAE 132 Query: 1093 CCQLLIARGANLAAKNASGSTPL 1161 C + L+ GA++ A + + TPL Sbjct: 133 CVRALLESGASVNALDYNNDTPL 155 Score = 54.7 bits (130), Expect = 2e-06 Identities = 54/198 (27%), Positives = 82/198 (41%) Frame = +1 Query: 568 HEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIH 747 H+ V L+ G ++N + L AC + V+ L+ A ++ D N T +H Sbjct: 34 HDNVEDLIRGGADVNC-THGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNR-TVLH 91 Query: 748 FAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLT 927 +AA A C+ VL +Y + PN L+ + T Sbjct: 92 YAAEKDEA-CVE-VLLEYGAN-PNALDGNRD----------------------------T 120 Query: 928 PLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLL 1107 PLH AA + ECV+ LL+ GASV+ + + TPL +AA GN +L Sbjct: 121 PLHWAAFKNNAECVRALLESGASVNALDYNN----------DTPLSWAAMKGNLESVSIL 170 Query: 1108 IARGANLAAKNASGSTPL 1161 + GA + N G TP+ Sbjct: 171 LDYGAEVRVINLIGQTPI 188 Score = 49.7 bits (117), Expect = 5e-05 Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Frame = +1 Query: 448 ARDGDLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 A + D LLEY NP + G R++PLH+AA + + E V LLESG +N + Sbjct: 93 AAEKDEACVEVLLEYGANPN----ALDGNRDTPLHWAAFKNNAECVRALLESGASVNALD 148 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAI 744 Y T L A G+ E V L+ + A + R L G T I Sbjct: 149 YNNDTPLSWAAMKGNLESVSILLDYGAEV-RVINLIGQTPI 188
>Q96Q27:ASB2_HUMAN Ankyrin repeat and SOCS box protein 2 - Homo sapiens (Human)| Length = 587 Score = 62.8 bits (151), Expect = 6e-09 Identities = 74/327 (22%), Positives = 134/327 (40%), Gaps = 11/327 (3%) Frame = +1 Query: 415 CSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLE 594 C+ L + DL+ + L+ ++ + +G +PL AA G E + L + Sbjct: 187 CNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYG--ITPLFVAAQSGQLEALRFLAK 244 Query: 595 SGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR 774 G +IN + +AL +AC+ H EVV+ L+ A+ ++T+ +G +H A+ G+ R Sbjct: 245 YGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTN-KDGLLPLHIASKKGNYR 303 Query: 775 CLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNG 954 ++++L ++T+ R S G++PLH+AA Sbjct: 304 IVQMLLP--------VTSRTRIRRS-----------------------GVSPLHLAAERN 332 Query: 955 HVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAA 1134 H E ++ LL V+ + + S+ L++A N +LL+ GA+ Sbjct: 333 HDEVLEALLSARFDVNTPLAPERARL-YEDRRSSALYFAVVNNNVYATELLLQHGAD--- 388 Query: 1135 KNASGSTPLMVA--HSW---------HRNSIEEILSNEPGGQIRTLPSPYLCLPLMSIMS 1281 N +PL+VA H H +I+ ++ P T+ CL L+ Sbjct: 389 PNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLL---- 444 Query: 1282 IARECGWRYLNKSPVCIDPCAVCLDGS 1362 ++L +PC CL G+ Sbjct: 445 -------KFLMDLGCDGEPCFSCLYGN 464 Score = 53.5 bits (127), Expect = 3e-06 Identities = 61/228 (26%), Positives = 93/228 (40%), Gaps = 1/228 (0%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 R +PL+ A + + E V +L++ + N R RG TAL ++ EV+Q L+ A + Sbjct: 157 RETPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKV 216 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + G T + AA G LR LA Y AD Sbjct: 217 ESKN-AYGITPLFVAAQSGQLEALRF-LAKY--------------------GAD------ 248 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 +N +A + L+ A N H E V+ LL GA ++ + G PLH Sbjct: 249 ---INTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKD----------GLLPLHI 295 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILS 1209 A+ GN Q+L+ + + SG +PL + A H +E +LS Sbjct: 296 ASKKGNYRIVQMLLPVTSRTRIRR-SGVSPLHLAAERNHDEVLEALLS 342 Score = 50.4 bits (119), Expect = 3e-05 Identities = 53/212 (25%), Positives = 78/212 (36%), Gaps = 1/212 (0%) Frame = +1 Query: 538 PLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT 717 PL A G E + +++ G + N G L +A YG ++ L Sbjct: 60 PLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQ 119 Query: 718 DYLNGGTAIHFAALHGHARCL-RLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 L TA++ A GH CL L+ A P I N +S E Sbjct: 120 RTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISN-------KSRE-------------- 158 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 TPL+ A + E V++L+ A + G T LH + Sbjct: 159 ----------TPLYKACERKNAEAVKILVQHNADTNH----------RCNRGWTALHESV 198 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 + Q+L++ GA + +KNA G TPL VA Sbjct: 199 SRNDLEVMQILVSGGAKVESKNAYGITPLFVA 230
>Q9W0T5:PYX_DROME Transient receptor potential channel pyrexia - Drosophila| melanogaster (Fruit fly) Length = 956 Score = 62.4 bits (150), Expect = 7e-09 Identities = 69/268 (25%), Positives = 114/268 (42%), Gaps = 6/268 (2%) Frame = +1 Query: 385 FLSLVGNSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQG 564 FL L+ +S C+ + L+ + G ++ LL++ + GR +PLH+A + Sbjct: 89 FLELMTDSADCNLA---LICCSVFGSVENTLFLLKHYNADPNVADSRGR-TPLHFACCRA 144 Query: 565 HHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAI 744 + I +LL+ G + N + R + + C V L+L + +A+ Sbjct: 145 NAPIAKVLLDFGADPNRWDARKEVTSLH-CAASSKSVECILLLLRRKASINIGIEKRSAL 203 Query: 745 HFAALHGHARCLRLVL---ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKA- 912 H+A C+ ++L AD P+ P +T ++ A L + ++ Sbjct: 204 HYAIDVNAVDCVEILLKYGAD--PNTPQVYTETPLHTASAAGFAKCVQLLLSHNADVRSQ 261 Query: 913 --DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 +G +T LH+AA N +VEC +LLL+ A V S TPLH A + Sbjct: 262 FGEGKVTALHLAAENDYVECARLLLEHRAEVDCRN----------ASHQTPLHLACLSQS 311 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLMVA 1170 LLI+ GAN+ A G T L A Sbjct: 312 IGTVDLLISYGANVNAVYRDGRTALHAA 339 Score = 57.8 bits (138), Expect = 2e-07 Identities = 58/193 (30%), Positives = 87/193 (45%), Gaps = 1/193 (0%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFG-GRNSPLHYAAAQGHHEIVSLLLESGVEIN 612 L +A+ G + + LL +N + S FG G+ + LH AA + E LLLE E++ Sbjct: 236 LHTASAAGFAKCVQLLLSHNADVR--SQFGEGKVTALHLAAENDYVECARLLLEHRAEVD 293 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 RN QT L AC V L+ + AN++ Y +G TA+H AA+ +R L Sbjct: 294 CRNASHQTPLHLACLSQSIGTVDLLISYGANVNAV-YRDGRTALH-AAIVKQSRSLDCCN 351 Query: 793 ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ 972 A ++ +V+ AD + G TPLH+AALN CV Sbjct: 352 ALL-------------KAGADVNKAD--------------NYGYTPLHIAALNEFSSCVY 384 Query: 973 LLLDLGASVSEVT 1011 ++ GA ++ T Sbjct: 385 TFIEHGADITART 397
>P97570:PA2G6_RAT 85 kDa calcium-independent phospholipase A2 - Rattus norvegicus (Rat)| Length = 751 Score = 62.4 bits (150), Expect = 7e-09 Identities = 67/259 (25%), Positives = 101/259 (38%), Gaps = 1/259 (0%) Frame = +1 Query: 403 NSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVS 582 N GC+ L A R GD + L++Y + G + HYA + +++ Sbjct: 148 NEEGCTP----LHLACRKGDSEILVELVQYCHAQMDVTDNKGETA-FHYAVQGDNPQVLQ 202 Query: 583 LL-LESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAAL 759 LL + +N N +G T L ACQ G E+V+ L+L NA + GG IH A Sbjct: 203 LLGKNASAGLNQVNNQGLTPLHLACQMGKQEMVRVLLLCNARCNIMG--PGGFPIHTAMK 260 Query: 760 HGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHM 939 C ++++ S ++ D G +PLH Sbjct: 261 FSQKGCAEMIIS---------------MDSNQIHSKD-------------PRYGASPLHW 292 Query: 940 AALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG 1119 A + E ++LL G V + SG+T LH A C +L+ G Sbjct: 293 AK---NAEMARMLLKRGCDVDSTS----------ASGNTALHVAVTRNRFDCVMVLLTYG 339 Query: 1120 ANLAAKNASGSTPLMVAHS 1176 AN A+ G+TPL +A S Sbjct: 340 ANAGARGEHGNTPLHLAMS 358 Score = 43.1 bits (100), Expect = 0.005 Identities = 56/214 (26%), Positives = 88/214 (41%), Gaps = 25/214 (11%) Frame = +1 Query: 619 NYRGQTALMQACQYGHWEVVQTLMLF-NANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 N G T L AC+ G E++ L+ + +A + TD G TA H+A + + L+L+ Sbjct: 148 NEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDN-KGETAFHYAVQGDNPQVLQLLGK 206 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 + + NQ GLTPLH+A G E V++ Sbjct: 207 NASAGLNQVNNQ-----------------------------GLTPLHLACQMGKQEMVRV 237 Query: 976 LLDLGA---------------------SVSEVTIE-DGTTIDLLGS--GSTPLHYAACGG 1083 LL A +E+ I D I G++PLH+A Sbjct: 238 LLLCNARCNIMGPGGFPIHTAMKFSQKGCAEMIISMDSNQIHSKDPRYGASPLHWAK--- 294 Query: 1084 NAVCCQLLIARGANLAAKNASGSTPLMVAHSWHR 1185 NA ++L+ RG ++ + +ASG+T L VA + +R Sbjct: 295 NAEMARMLLKRGCDVDSTSASGNTALHVAVTRNR 328 Score = 35.8 bits (81), Expect = 0.74 Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 1/97 (1%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 G TPLH+A G E + L+ + +VT G T HYA G N Sbjct: 151 GCTPLHLACRKGDSEILVELVQYCHAQMDVTD---------NKGETAFHYAVQGDNPQVL 201 Query: 1099 QLLIAR-GANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 QLL A L N G TPL +A + + +L Sbjct: 202 QLLGKNASAGLNQVNNQGLTPLHLACQMGKQEMVRVL 238
>P19838:NFKB1_HUMAN Nuclear factor NF-kappa-B p105 subunit - Homo sapiens (Human)| Length = 968 Score = 62.4 bits (150), Expect = 7e-09 Identities = 75/280 (26%), Positives = 111/280 (39%), Gaps = 51/280 (18%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLE------SGVEINLRNYRGQTALMQACQYGHWEVVQTLML 693 +S LH A H ++V LLE S IN+RN QT L A +VV+ L+ Sbjct: 544 DSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLR 603 Query: 694 FNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADF 873 A++ D L G + +H AA GH + L ++L KH+ + + D Sbjct: 604 AGADLSLLDRL-GNSVLHLAAKEGHDKVLSILL--------------KHKKAALLLDHPN 648 Query: 874 DDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTT-------- 1029 D GL +H+A ++ + C+ LL+ GA V+ + G T Sbjct: 649 GD-------------GLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEH 695 Query: 1030 --IDLLG---------------SGSTPLHYAACGGNAVCCQLLIARGANLAAKN------ 1140 I L G G+TPLH AA G+ LL A GA+ +N Sbjct: 696 DNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYD 755 Query: 1141 --------------ASGSTPLMVAHSWHRNSIEEILSNEP 1218 G+TPL +A SW + +IL+ +P Sbjct: 756 LDDSWENAGEDEGVVPGTTPLDMATSW---QVFDILNGKP 792 Score = 41.6 bits (96), Expect = 0.014 Identities = 44/192 (22%), Positives = 74/192 (38%), Gaps = 27/192 (14%) Frame = +1 Query: 676 VQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEE 855 V+ L+ ++ NG + +H A +H H++ +R +L E Sbjct: 525 VKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLL--------------------E 564 Query: 856 VSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTID 1035 V+ DD ++N + D TPLH+A + + V+ LL GA +S + + + Sbjct: 565 VTSGLISDD----IINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLH 620 Query: 1036 LL--------------------------GSGSTPLHYAACGGNAVCCQLLIARGANL-AA 1134 L G G +H A + C LL+A GA++ A Sbjct: 621 LAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQ 680 Query: 1135 KNASGSTPLMVA 1170 + SG T L +A Sbjct: 681 EQKSGRTALHLA 692
>Q3SX45:ASB2_BOVIN Ankyrin repeat and SOCS box protein 2 - Bos taurus (Bovine)| Length = 633 Score = 62.4 bits (150), Expect = 7e-09 Identities = 74/327 (22%), Positives = 133/327 (40%), Gaps = 11/327 (3%) Frame = +1 Query: 415 CSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLE 594 C+ L + DL+ L+ ++ + +G +PL AA G E + L + Sbjct: 233 CNRGWTALHESVARNDLEVMEILVSGGAKVEAKNAYG--ITPLFVAAQSGQLEALRFLAK 290 Query: 595 SGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR 774 G +IN + +AL +AC+ GH EVV+ L+ A+ ++T+ +G +H A+ G+ R Sbjct: 291 YGADINTQASDSASALYEACKNGHEEVVEFLLSQGADANKTN-KDGMLPLHIASKKGNYR 349 Query: 775 CLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNG 954 ++++L ++T+ R S G++PLH+AA Sbjct: 350 IVQMLLP--------VTSRTRVRRS-----------------------GISPLHLAAERN 378 Query: 955 HVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAA 1134 + E ++ LL V+ + + S+ L++A N +LL+ GA+ Sbjct: 379 NDEVLEALLGARFDVNAPLAPERARL-YEDRRSSALYFAVVNNNVYATELLLLAGAD--- 434 Query: 1135 KNASGSTPLMVA--HSW---------HRNSIEEILSNEPGGQIRTLPSPYLCLPLMSIMS 1281 N PL+VA H H +I+ ++ P T+ CL L+ Sbjct: 435 PNRDVINPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLL---- 490 Query: 1282 IARECGWRYLNKSPVCIDPCAVCLDGS 1362 ++L +PC CL G+ Sbjct: 491 -------KFLMDLGCNGEPCFSCLYGN 510 Score = 62.0 bits (149), Expect = 1e-08 Identities = 65/266 (24%), Positives = 114/266 (42%), Gaps = 9/266 (3%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L AA G L +AL P + T + L+ A +GH + + LL++G E ++ Sbjct: 140 LHEAAYYGQLNCLKALHRAYPAVIDQRTLQ-EETALYLATCRGHVDCLQFLLQAGAEPDI 198 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANI-HRTDYLNGGTAIHFAALHGHARCLRLVL 792 N +T L +AC+ + E V+ L+ + A+ HR + G TA+H + + +++ Sbjct: 199 SNKSRETPLYKACERKNVEAVRILVQYKADTNHRCN--RGWTALHESVARNDLEVMEILV 256 Query: 793 A--------DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAAL 948 + + P F+ + A + D +N +A + L+ A Sbjct: 257 SGGAKVEAKNAYGITPLFVAAQSGQLEALRFLAKYGAD-----INTQASDSASALYEACK 311 Query: 949 NGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANL 1128 NGH E V+ LL GA ++ + G PLH A+ GN Q+L+ + Sbjct: 312 NGHEEVVEFLLSQGADANKTNKD----------GMLPLHIASKKGNYRIVQMLLPVTSRT 361 Query: 1129 AAKNASGSTPLMVAHSWHRNSIEEIL 1206 + SG +PL +A + + + E L Sbjct: 362 RVRR-SGISPLHLAAERNNDEVLEAL 386 Score = 54.3 bits (129), Expect = 2e-06 Identities = 62/252 (24%), Positives = 100/252 (39%), Gaps = 1/252 (0%) Frame = +1 Query: 418 SASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLES 597 S S E +++A G QE + +YN S+ P+ A + E ++ ++++ Sbjct: 71 SVSPESALTSAPKGLFQEV--MQKYN---RSKSSQLAPVDPVLKAIKEDDEEALTAMIKA 125 Query: 598 GVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARC 777 G ++ N G L +A YG ++ L + L TA++ A GH C Sbjct: 126 GKNLSEPNKEGWLPLHEAAYYGQLNCLKALHRAYPAVIDQRTLQEETALYLATCRGHVDC 185 Query: 778 LRLVL-ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNG 954 L+ +L A P I N +S E TPL+ A Sbjct: 186 LQFLLQAGAEPDISN-------KSRE------------------------TPLYKACERK 214 Query: 955 HVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAA 1134 +VE V++L+ A + G T LH + + ++L++ GA + A Sbjct: 215 NVEAVRILVQYKADTNH----------RCNRGWTALHESVARNDLEVMEILVSGGAKVEA 264 Query: 1135 KNASGSTPLMVA 1170 KNA G TPL VA Sbjct: 265 KNAYGITPLFVA 276
>Q865U8:ANKR1_PIG Ankyrin repeat domain-containing protein 1 - Sus scrofa (Pig)| Length = 319 Score = 62.4 bits (150), Expect = 7e-09 Identities = 54/187 (28%), Positives = 81/187 (43%) Frame = +1 Query: 631 QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPS 810 +TAL +AC GH +V+ L+ A I D L TAIH+A+ G+ L+L+L Sbjct: 154 RTALHRACLEGHLAIVEKLIEAGAQIEFRDMLES-TAIHWASRGGNLDVLKLLL------ 206 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 ++S D K+++ T LH+A GH EC + L+ Sbjct: 207 ----------NKGAKISARD-------KLLS-------TALHVAVRTGHYECAEHLIACE 242 Query: 991 ASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 A ++ E G TPLH A +LLI GA+L KN +G TP+ + Sbjct: 243 ADLNAKDRE----------GDTPLHDAVRLNRYKMIRLLITYGADLNVKNCAGKTPMDLV 292 Query: 1171 HSWHRNS 1191 +W + Sbjct: 293 LNWQNGT 299 Score = 55.5 bits (132), Expect = 9e-07 Identities = 47/171 (27%), Positives = 74/171 (43%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + + LH A +GH IV L+E+G +I R+ TA+ A + G+ +V++ L+ A I Sbjct: 153 KRTALHRACLEGHLAIVEKLIEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKI 212 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 D L TA+H A GH C ++A +AD Sbjct: 213 SARDKLL-STALHVAVRTGHYECAEHLIA---------------------CEAD------ 244 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +N K G TPLH A + ++LL+ GA ++ T +DL+ Sbjct: 245 ---LNAKDREGDTPLHDAVRLNRYKMIRLLITYGADLNVKNCAGKTPMDLV 292 Score = 46.2 bits (108), Expect = 6e-04 Identities = 31/110 (28%), Positives = 57/110 (51%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 L EA A +E+ L ++ +H+A+ G+ +++ LLL G +I+ R+ TAL Sbjct: 172 LIEAGAQIEFRDML--------ESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTAL 223 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 A + GH+E + L+ A+++ D G T +H A + +RL++ Sbjct: 224 HVAVRTGHYECAEHLIACEADLNAKD-REGDTPLHDAVRLNRYKMIRLLI 272 Score = 45.1 bits (105), Expect = 0.001 Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 23/117 (19%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTID-------------LLGSG----- 1050 T LH A L GH+ V+ L++ GA + + + T I LL G Sbjct: 155 TALHRACLEGHLAIVEKLIEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKISA 214 Query: 1051 -----STPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 ST LH A G+ C + LIA A+L AK+ G TPL A +R + +L Sbjct: 215 RDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLL 271 Score = 33.5 bits (75), Expect = 3.7 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 9/100 (9%) Frame = +1 Query: 370 WASMG----FLSLVGNSFGCSASGERLVSAA-----RDGDLQEARALLEYNPRLARYSTF 522 WAS G L L+ N ++ ++L+S A R G + A L+ L Sbjct: 192 WASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDRE 251 Query: 523 GGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 G ++PLH A ++++ LL+ G ++N++N G+T + Sbjct: 252 G--DTPLHDAVRLNRYKMIRLLITYGADLNVKNCAGKTPM 289
>Q15327:ANKR1_HUMAN Ankyrin repeat domain-containing protein 1 - Homo sapiens (Human)| Length = 319 Score = 62.4 bits (150), Expect = 7e-09 Identities = 55/187 (29%), Positives = 80/187 (42%) Frame = +1 Query: 631 QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPS 810 +TAL +AC GH +V+ LM A I D L TAIH+A+ G+ L+L+L Sbjct: 154 RTALHRACLEGHLAIVEKLMEAGAQIEFRDMLES-TAIHWASRGGNLDVLKLLL------ 206 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 ++S D K+++ T LH+A GH EC + L+ Sbjct: 207 ----------NKGAKISARD-------KLLS-------TALHVAVRTGHYECAEHLIACE 242 Query: 991 ASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 A ++ E G TPLH A +LLI GA+L KN +G TP+ + Sbjct: 243 ADLNAKDRE----------GDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLV 292 Query: 1171 HSWHRNS 1191 W + Sbjct: 293 LHWQNGT 299 Score = 54.3 bits (129), Expect = 2e-06 Identities = 47/171 (27%), Positives = 74/171 (43%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + + LH A +GH IV L+E+G +I R+ TA+ A + G+ +V++ L+ A I Sbjct: 153 KRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKI 212 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 D L TA+H A GH C ++A +AD Sbjct: 213 SARDKLL-STALHVAVRTGHYECAEHLIA---------------------CEAD------ 244 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +N K G TPLH A + ++LL+ GA ++ T +DL+ Sbjct: 245 ---LNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLV 292 Score = 47.4 bits (111), Expect = 2e-04 Identities = 31/110 (28%), Positives = 57/110 (51%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 L EA A +E+ L ++ +H+A+ G+ +++ LLL G +I+ R+ TAL Sbjct: 172 LMEAGAQIEFRDML--------ESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTAL 223 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 A + GH+E + L+ A+++ D G T +H A + +RL++ Sbjct: 224 HVAVRTGHYECAEHLIACEADLNAKD-REGDTPLHDAVRLNRYKMIRLLI 272 Score = 45.1 bits (105), Expect = 0.001 Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 23/117 (19%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTID-------------LLGSG----- 1050 T LH A L GH+ V+ L++ GA + + + T I LL G Sbjct: 155 TALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKISA 214 Query: 1051 -----STPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 ST LH A G+ C + LIA A+L AK+ G TPL A +R + +L Sbjct: 215 RDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLL 271 Score = 33.9 bits (76), Expect = 2.8 Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 9/110 (8%) Frame = +1 Query: 370 WASMG----FLSLVGNSFGCSASGERLVSAA-----RDGDLQEARALLEYNPRLARYSTF 522 WAS G L L+ N ++ ++L+S A R G + A L+ L Sbjct: 192 WASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDRE 251 Query: 523 GGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWE 672 G ++PLH A ++++ LL+ G ++N++N G+T + HW+ Sbjct: 252 G--DTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVL---HWQ 296
>Q9GL21:UACA_CANFA Uveal autoantigen with coiled-coil domains and ankyrin repeats -| Canis familiaris (Dog) Length = 1415 Score = 62.0 bits (149), Expect = 1e-08 Identities = 78/294 (26%), Positives = 114/294 (38%), Gaps = 23/294 (7%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 +RL+ AA GD+++ ++L GR S H A++G+ E ++ +L GV+I Sbjct: 38 DRLMKAAERGDVEKVSSILAKKGINPGKLDVEGR-SAFHVVASKGNLECLNAILIHGVDI 96 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 + G+ AL A +YGH +Q L+ +N D L G TA+H AA Sbjct: 97 TTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHAD-LQGRTALHDAA----------- 144 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 +AD SI + H +S D D G TPL +A Sbjct: 145 MADCPSSIQLLCD---HGASVNAKDVD----------------GRTPLVLATQMCRPAIC 185 Query: 970 QLLLDLGASVS----------------------EVTIEDGTTIDLLGS-GSTPLHYAACG 1080 QLL+D GA ++ EV +++G + LL + G +YA G Sbjct: 186 QLLIDRGAEINSRDKQNRTALMLGCEYGCKDAVEVLLKNGADVSLLDALGHDSSYYARIG 245 Query: 1081 GNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLP 1242 N LL K AS +T N E+ P Q R LP Sbjct: 246 DNLDILTLL---------KTASENT----------NKGRELWKKGPSLQQRNLP 280
>Q9WV48:SHAN1_RAT SH3 and multiple ankyrin repeat domains protein 1 - Rattus norvegicus| (Rat) Length = 2167 Score = 62.0 bits (149), Expect = 1e-08 Identities = 70/248 (28%), Positives = 106/248 (42%), Gaps = 10/248 (4%) Frame = +1 Query: 499 RLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY-RGQTALMQACQY-GHWE 672 +LA+ T G L Y G + V+ LL+ G++ N + G+T L A Q G E Sbjct: 170 QLAKLHTKTGLKKFLEYVQL-GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVE 228 Query: 673 VVQTLMLFNANIHRTDYL--NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRS 846 V++TL L A+I D+ +G TA+H AA H CL L + PN+ ++ Sbjct: 229 VIRTLCLGGAHI---DFRARDGMTALHKAACARH--CLALTALLDLGGSPNYKDRRGLTP 283 Query: 847 SEEVSDADFDDDGLVKMVNWKA------DGGLTPLHMAALNGHVECVQLLLDLGASVSEV 1008 + D ++ +A + G +H A GH + ++ LL GA Sbjct: 284 LFHTAMVGGDPRCCELLLYNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQ 343 Query: 1009 TIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRN 1188 SG+T LH A C ++L+ RGAN KN +G TP VA Sbjct: 344 N----------ASGNTALHICALYNKETCARILLYRGANKDVKNNNGQTPFQVAVIAGNF 393 Query: 1189 SIEEILSN 1212 + E++ N Sbjct: 394 ELGELIRN 401
>Q60778:IKBB_MOUSE NF-kappa-B inhibitor beta - Mus musculus (Mouse)| Length = 359 Score = 62.0 bits (149), Expect = 1e-08 Identities = 71/247 (28%), Positives = 104/247 (42%), Gaps = 21/247 (8%) Frame = +1 Query: 484 LEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLL--ESGVE-INLRNYRGQTALMQAC 654 L + P + Y T G ++ LH A H + LL +G E ++L+N GQTAL A Sbjct: 44 LSWAPLVFGYVTEDG-DTALHLAVIHQHEPFLDFLLGFSAGHEYLDLQNDLGQTALHLAA 102 Query: 655 QYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPN----- 819 G V+ L A + + G TA+H A A VL PS P Sbjct: 103 ILGEASTVEKLYAAGAGVLVAER-GGHTALHLAC-RVRAHTCACVLLQPRPSHPRDASDT 160 Query: 820 FLNQ-------TKHRSSEEVSDADFDDDGLVKMVNWKAD------GGLTPLHMAALNGHV 960 +L Q T H + S + +++ + +W+ G TPLH+A ++ Sbjct: 161 YLTQSQDCTPDTSHAPAAVDSQPNPENEEEPRDEDWRLQLEAENYDGHTPLHVAVIHKDA 220 Query: 961 ECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKN 1140 E V+LL D GA +++ G TPLH A A +LL+ GA+ A+ Sbjct: 221 EMVRLLRDAGADLNKPEPT---------CGRTPLHLAVEAQAASVLELLLKAGADPTARM 271 Query: 1141 ASGSTPL 1161 G TPL Sbjct: 272 YGGRTPL 278
>Q3KP44:ANR55_HUMAN Ankyrin repeat domain-containing protein 55 - Homo sapiens (Human)| Length = 613 Score = 62.0 bits (149), Expect = 1e-08 Identities = 76/298 (25%), Positives = 118/298 (39%), Gaps = 41/298 (13%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA +GD+ A++ +P + G +PL +A + + V LLL+ G IN+++ Sbjct: 33 AASNGDVNALTAVIREDPSILECCDSEGC-TPLMHAVSGRQADTVKLLLKMGANINMQDA 91 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G+T+L A G E +L L N H NG +H A R L ++L Sbjct: 92 YGRTSLCLATYLGWLEGCVSL-LRNGAKHNIPDKNGRLPLHAATAEPDMRLLTVLLQQSN 150 Query: 805 PSIPN--------------FLNQTKHRSSEEVSDAD---FDDDGLVKM------------ 897 S N F NQ +H AD D D + Sbjct: 151 ISEINHQDNEGMTPLHWAAFHNQPQHTQMLLKKGADPTLVDKDFKTALHWAVQSGNRILC 210 Query: 898 ------------VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +N+ + G T +H+AA G + + L A V E ++ +D+ Sbjct: 211 SIILSHHQGPSIINYDDESGKTCVHIAAAAGFSDIIHEL----ARVPECNLQ---ALDV- 262 Query: 1042 GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNE 1215 TPLH+AA G A C Q L+ G + ++ + STPL A + ++LS E Sbjct: 263 -DDRTPLHWAAAAGKAECVQSLLELGMDSNLRDINESTPLAYALYCGHTACVKLLSQE 319
>P59672:ANKS1_MOUSE Ankyrin repeat and SAM domain-containing protein 1A - Mus musculus| (Mouse) Length = 1150 Score = 62.0 bits (149), Expect = 1e-08 Identities = 76/268 (28%), Positives = 112/268 (41%), Gaps = 9/268 (3%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQG-------HHEIVSLL 588 + L+ AAR G L LL RL+ S FGG G H + SLL Sbjct: 5 QELLEAARTGHLPAVEKLLS-GKRLS--SGFGGGGGGSGSGGGSGGGGLGSSSHPLSSLL 61 Query: 589 -LESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHG 765 + G +N + G T L A GH +VV+ L+ +A + D G +H AA G Sbjct: 62 SMWRGPNVNCVDSTGYTPLHHAALNGHRDVVEVLLRNDALTNVADS-KGCYPLHLAAWKG 120 Query: 766 HARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAA 945 A+ +RL++ PS Q E FD +N K + T LH AA Sbjct: 121 DAQIVRLLIQQG-PSHTRVNEQNALEIRELKKYGPFDP-----YINAKNNDNETALHCAA 174 Query: 946 LNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGAN 1125 GH E V+ LL+ +++ T+ + TPL AA G +LL+ N Sbjct: 175 QYGHTEVVKALLE---ELTDPTMRNNKF-------ETPLDLAALYGRLEVVKLLLGAHPN 224 Query: 1126 LAAKNASGSTPL-MVAHSWHRNSIEEIL 1206 L + + TPL + A + H+ ++ +L Sbjct: 225 LLSCSTRKHTPLHLAARNGHKAVVQVLL 252 Score = 58.9 bits (141), Expect = 8e-08 Identities = 64/227 (28%), Positives = 92/227 (40%), Gaps = 22/227 (9%) Frame = +1 Query: 388 LSLVGNSFGCSASGERLVSAARDGDLQEARALLEYNP--------------RLARYSTF- 522 L+ V +S GC L AA GD Q R L++ P L +Y F Sbjct: 101 LTNVADSKGCYP----LHLAAWKGDAQIVRLLIQQGPSHTRVNEQNALEIRELKKYGPFD 156 Query: 523 -------GGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQ 681 + LH AA GH E+V LLE + +RN + +T L A YG EVV+ Sbjct: 157 PYINAKNNDNETALHCAAQYGHTEVVKALLEELTDPTMRNNKFETPLDLAALYGRLEVVK 216 Query: 682 TLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVS 861 L+ + N+ T +H AA +GH ++++L Sbjct: 217 LLLGAHPNLLSCS-TRKHTPLHLAARNGHKAVVQVLL----------------------- 252 Query: 862 DADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVS 1002 DA D N++ + G + LH AAL G + VQ+LL G V+ Sbjct: 253 DAGMDS-------NYQTEMG-SALHEAALFGKTDVVQILLAAGIDVN 291
>Q9J513:V222_FOWPV Putative ankyrin repeat protein FPV222 - Fowlpox virus (FPV)| Length = 747 Score = 61.6 bits (148), Expect = 1e-08 Identities = 54/210 (25%), Positives = 101/210 (48%), Gaps = 9/210 (4%) Frame = +1 Query: 568 HEIVSL--LLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA--NIHRTDYLNGG 735 +++VS+ LE G+ N +N T L A ++ + ++++ L+ A NI+ +D++ Sbjct: 17 NDVVSVRKYLEKGINPNEKNKDNCTMLYTAVEHRYIDIIKLLLDHGADPNIYSSDHM--- 73 Query: 736 TAIHFAALHGHARCLRLVLADY--VPSIPNFLNQT---KHRSSEEVSDADFDDDGLVKMV 900 T +H ++ R + ++ Y + ++ N+ N + E++ + LV M Sbjct: 74 TPLHSVSVIIPIRKISKLITKYGNLVTLANYRNTFFVYNENRNLEIAKMLIQNGALVNMN 133 Query: 901 NWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACG 1080 N K +TPLH+A+ +G + V+LLL GA+ + +T G T LHY+ Sbjct: 134 NMK---NITPLHIASSSGSYKMVELLLLHGANTNALT----------SYGETSLHYSVSS 180 Query: 1081 GNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 + +LLI G N+ N T L++A Sbjct: 181 NDLNISELLIENGTNVNVANKDSITALIIA 210 Score = 39.3 bits (90), Expect = 0.067 Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 3/91 (3%) Frame = +1 Query: 529 RNSPLHYAAAQGHHE---IVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 +N+P HYA E + LL +G NL N +G+T L AC+Y + E V+ L+ Sbjct: 362 QNTPAHYAVKLPISESCKYLKLLKLAGASFNLTNRKGRTPLHTACKYNNTEAVKYLIESG 421 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 + + D ++ T +++A + ++++L Sbjct: 422 CDTNIVDVMS-FTPLNYAVYYEREDTVKILL 451 Score = 35.4 bits (80), Expect = 0.97 Identities = 41/177 (23%), Positives = 79/177 (44%), Gaps = 1/177 (0%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESG-VEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 +PL+YA + V +LLESG V+ NL +Y+ + ++QA + + +++ ML NA I Sbjct: 433 TPLNYAVYYEREDTVKILLESGCVDPNLCDYKEVSPIIQAIKRNNKNIIK--MLLNAGID 490 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 +N +H A + L+ +L S EV+ DD V Sbjct: 491 -IKPINECYGLHMLAALHNKDLLKWLLCTI--------------SELEVNGV---DDHYV 532 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 + ++ A+ + +++L++ G +++VT D T ++ S ++ L Sbjct: 533 PLASYVAE-----------LSDIRIMEILIEKGLDLNKVTGPDETMFTMIFSATSDL 578 Score = 33.9 bits (76), Expect = 2.8 Identities = 21/82 (25%), Positives = 40/82 (48%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A+ G + LL + +++G + LHY+ + I LL+E+G +N+ N Sbjct: 144 ASSSGSYKMVELLLLHGANTNALTSYG--ETSLHYSVSSNDLNISELLIENGTNVNVANK 201 Query: 625 RGQTALMQACQYGHWEVVQTLM 690 TAL+ A + ++V+ L+ Sbjct: 202 DSITALIIAVEIMSIDLVRLLL 223
>Q5RF15:TNI3K_PONPY Serine/threonine-protein kinase TNNI3K - Pongo pygmaeus (Orangutan)| Length = 618 Score = 61.6 bits (148), Expect = 1e-08 Identities = 69/226 (30%), Positives = 95/226 (42%), Gaps = 17/226 (7%) Frame = +1 Query: 457 GDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQT 636 G+ R L+ R +R + G + LH A + + E+++ LL G +I Y G T Sbjct: 79 GNKSHIRTLMLKGLRPSRLTRNGF--TALHLAVYKDNAELITSLLHGGADIQQVGYGGLT 136 Query: 637 ALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL---AD--- 798 AL A GH E L+ AN++ D + T +H AA +GH + RL+L AD Sbjct: 137 ALHIATIAGHLEAADVLLQHGANVNIQDAV-FFTPLHIAAYYGHEQVTRLLLKFGADVNV 195 Query: 799 ---------YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALN 951 ++ S FLN K EE S AD VN + + PLH + Sbjct: 196 SGEVGDRPLHLASAKGFLNIAK-LLMEEGSKAD---------VNAQDNEDHVPLHFCSRF 245 Query: 952 GHVECVQLLL--DLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGG 1083 GH + V+ LL DL V I G TPLH A G Sbjct: 246 GHHDIVKYLLQNDLEVQPHVVNI----------YGDTPLHLACYNG 281 Score = 56.6 bits (135), Expect = 4e-07 Identities = 81/321 (25%), Positives = 129/321 (40%), Gaps = 63/321 (19%) Frame = +1 Query: 520 FGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 +GG + LH A GH E +LL+ G +N+++ T L A YGH +V + L+ F Sbjct: 132 YGGLTA-LHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 190 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDD 879 A+++ + + G +H A+ G +L++ + + N + H S F Sbjct: 191 ADVNVSGEV-GDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCS--RFGH 247 Query: 880 DGLVK------------MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIED- 1020 +VK +VN D TPLH+A NG E + ++ + + S +T E+ Sbjct: 248 HDIVKYLLQNDLEVQPHVVNIYGD---TPLHLACYNGKFEVAKEIIQISGTES-LTKENI 303 Query: 1021 ------------GTTIDLL---------------GSGSTPLHYAACGGNAVCCQLLIARG 1119 G +IDL+ G T LH A G+ Q L+ G Sbjct: 304 FSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIHLVQFLLDNG 363 Query: 1120 A--NLAAKNASGS-------TPLMVAHSWHRNSIEEILS--------------NEPGGQI 1230 A NL A + S S T LM A+ ++I +L ++PGG Sbjct: 364 ADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLKHYKRPQDELPCNEYSQPGGDG 423 Query: 1231 RTLPSPYLCLPLMSIMSIARE 1293 + P PL I S+ +E Sbjct: 424 SYVSVP---SPLGKIKSMTKE 441
>Q10728:MYPT1_RAT Protein phosphatase 1 regulatory subunit 12A - Rattus norvegicus| (Rat) Length = 1032 Score = 61.6 bits (148), Expect = 1e-08 Identities = 67/254 (26%), Positives = 105/254 (41%), Gaps = 36/254 (14%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 A + G + V LL G +IN N G TAL QAC + ++V+ L+ ANI++ D N Sbjct: 47 ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPD--N 104 Query: 730 GGTAIHFAALHGHARCLRLVLADYV-----------------------PSIPNFLNQTKH 840 G + LH A C L +A+++ ++ L + Sbjct: 105 EG----WIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVN 160 Query: 841 RSSEEVSDADFDDD-------------GLVKMVNWKADGGLTPLHMAALNGHVECVQLLL 981 R ++ A +++ G + V GG T LH+AA G+ E ++LL+ Sbjct: 161 RQGVDIEAARKEEERIMLRDARQWLNSGHISDVRHAKSGG-TALHVAAAKGYTEVLKLLI 219 Query: 982 DLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL 1161 G +V I+D G TPLH AA G C++L+ ++ N G T Sbjct: 220 QAGY---DVNIKDY-------DGWTPLHAAAHWGKEEACRILVDNLCDMETVNKVGQTAF 269 Query: 1162 MVAHSWHRNSIEEI 1203 VA +EE+ Sbjct: 270 DVADEDILGYLEEL 283
>Q9DBR7:MYPT1_MOUSE Protein phosphatase 1 regulatory subunit 12A - Mus musculus (Mouse)| Length = 1004 Score = 61.6 bits (148), Expect = 1e-08 Identities = 67/254 (26%), Positives = 105/254 (41%), Gaps = 36/254 (14%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 A + G + V LL G +IN N G TAL QAC + ++V+ L+ ANI++ D N Sbjct: 47 ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPD--N 104 Query: 730 GGTAIHFAALHGHARCLRLVLADYV-----------------------PSIPNFLNQTKH 840 G + LH A C L +A+++ ++ L + Sbjct: 105 EG----WIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVN 160 Query: 841 RSSEEVSDADFDDD-------------GLVKMVNWKADGGLTPLHMAALNGHVECVQLLL 981 R ++ A +++ G + V GG T LH+AA G+ E ++LL+ Sbjct: 161 RQGVDIEAARKEEERVMLRDARQWLNSGHISDVRHAKSGG-TALHVAAAKGYTEVLKLLI 219 Query: 982 DLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL 1161 G +V I+D G TPLH AA G C++L+ ++ N G T Sbjct: 220 QAGY---DVNIKDY-------DGWTPLHAAAHWGKEEACRILVDNLCDMETVNKVGQTAF 269 Query: 1162 MVAHSWHRNSIEEI 1203 VA +EE+ Sbjct: 270 DVADEDILGYLEEL 283
>Q8BLD6:ANR55_MOUSE Ankyrin repeat domain-containing protein 55 - Mus musculus (Mouse)| Length = 626 Score = 61.6 bits (148), Expect = 1e-08 Identities = 66/268 (24%), Positives = 109/268 (40%), Gaps = 3/268 (1%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 AA +GD+ +++ +P + G +PL +A + + V LLL+ G IN ++ Sbjct: 33 AASNGDVNSLTSVIREDPSILECCDSEGC-TPLMHAVSGRQVDTVKLLLKMGANINTQDA 91 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 G+T+L A G W +L N H NG +H A R L ++L Sbjct: 92 YGRTSLCLATYLG-WLEGCVSLLRNGAKHNIPDKNGRLPLHAATAEPDVRLLIVLLQQ-- 148 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 + L++ H+ +E G+TPLH AA + + Q+LL Sbjct: 149 ----SSLSEINHQDTE----------------------GMTPLHWAAFHNRPQHTQMLLK 182 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKN---ASGST 1155 GA D T +D T LH+A GN + C ++++ + N SG T Sbjct: 183 KGA--------DPTLVD--KDFKTALHWAVQSGNRILCSIILSHRQGPSIINYDDESGKT 232 Query: 1156 PLMVAHSWHRNSIEEILSNEPGGQIRTL 1239 + +A + I L+ P ++ L Sbjct: 233 CVHIAAASGFGDIINDLAKVPECNLQAL 260 Score = 60.5 bits (145), Expect = 3e-08 Identities = 61/203 (30%), Positives = 92/203 (45%), Gaps = 9/203 (4%) Frame = +1 Query: 538 PLHYAAAQGHHEIVSLLLESGV--EINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 PLH A A+ ++ +LL+ EIN ++ G T L A + + Q L+ A+ Sbjct: 129 PLHAATAEPDVRLLIVLLQQSSLSEINHQDTEGMTPLHWAAFHNRPQHTQMLLKKGADPT 188 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYV-PSIPNFLNQTKHRSSEEVSDADFDD--D 882 D + TA+H+A G+ ++L+ PSI N+ +++ + + F D + Sbjct: 189 LVDK-DFKTALHWAVQSGNRILCSIILSHRQGPSIINYDDESGKTCVHIAAASGFGDIIN 247 Query: 883 GLVKMVNWKADG----GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSG 1050 L K+ TPLH AA +G ECVQ LLDLG D D+ + Sbjct: 248 DLAKVPECNLQALDVDDRTPLHWAAASGKAECVQSLLDLGM--------DSNLRDI--NE 297 Query: 1051 STPLHYAACGGNAVCCQLLIARG 1119 STPL YA G+ C +LL G Sbjct: 298 STPLAYALYCGHTACVRLLSREG 320 Score = 41.2 bits (95), Expect = 0.018 Identities = 22/51 (43%), Positives = 29/51 (56%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTL 687 +PLH+AAA G E V LL+ G++ NLR+ T L A GH V+ L Sbjct: 266 TPLHWAAASGKAECVQSLLDLGMDSNLRDINESTPLAYALYCGHTACVRLL 316 Score = 36.2 bits (82), Expect = 0.57 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +1 Query: 922 LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS-GSTPLHYAACGGNAVCC 1098 L ++ AA NG V S++ V ED + ++ S G TPL +A G Sbjct: 27 LAMVYQAASNGDVN----------SLTSVIREDPSILECCDSEGCTPLMHAVSGRQVDTV 76 Query: 1099 QLLIARGANLAAKNASGSTPLMVA 1170 +LL+ GAN+ ++A G T L +A Sbjct: 77 KLLLKMGANINTQDAYGRTSLCLA 100
>Q53RE8:ANR39_HUMAN Ankyrin repeat domain-containing protein 39 - Homo sapiens (Human)| Length = 183 Score = 61.6 bits (148), Expect = 1e-08 Identities = 39/117 (33%), Positives = 63/117 (53%) Frame = +1 Query: 442 SAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 SAA +GDL + L++ ++ + G + LHYA+ GH+ + LLESG + + + Sbjct: 37 SAALNGDLGRVKHLIQKAEDPSQPDSAG--YTALHYASRNGHYAVCQFLLESGAKCDAQT 94 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G TAL +A GH E+ + L+ +N D +G T++H AA GH L+L Sbjct: 95 HGGATALHRASYCGHTEIARLLLSHGSNPRVVDD-DGMTSLHKAAERGHGDICSLLL 150 Score = 45.1 bits (105), Expect = 0.001 Identities = 42/144 (29%), Positives = 58/144 (40%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA G V L++ + + + G TAL A + GH+ V Q L+ A + Sbjct: 38 AALNGDLGRVKHLIQKAEDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTH-G 96 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 G TA+H A+ GH RL+L+ H S+ V D Sbjct: 97 GATALHRASYCGHTEIARLLLS--------------HGSNPRVVD--------------- 127 Query: 910 ADGGLTPLHMAALNGHVECVQLLL 981 D G+T LH AA GH + LLL Sbjct: 128 -DDGMTSLHKAAERGHGDICSLLL 150 Score = 43.5 bits (101), Expect = 0.004 Identities = 37/122 (30%), Positives = 52/122 (42%), Gaps = 8/122 (6%) Frame = +1 Query: 877 DDGLVKMVNWKAD-------GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTID 1035 D G VK + KA+ G T LH A+ NGH Q LL+ GA T Sbjct: 43 DLGRVKHLIQKAEDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQT-------- 94 Query: 1036 LLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILSN 1212 G+T LH A+ G+ +LL++ G+N + G T L A H + +L + Sbjct: 95 --HGGATALHRASYCGHTEIARLLLSHGSNPRVVDDDGMTSLHKAAERGHGDICSLLLQH 152 Query: 1213 EP 1218 P Sbjct: 153 SP 154 Score = 37.4 bits (85), Expect = 0.26 Identities = 26/73 (35%), Positives = 32/73 (43%) Frame = +1 Query: 916 GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVC 1095 GG T LH A+ GH E +LLL G++ V G T LH AA G+ Sbjct: 96 GGATALHRASYCGHTEIARLLLSHGSNPRVVD----------DDGMTSLHKAAERGHGDI 145 Query: 1096 CQLLIARGANLAA 1134 C LL+ L A Sbjct: 146 CSLLLQHSPALKA 158 Score = 36.6 bits (83), Expect = 0.44 Identities = 29/89 (32%), Positives = 40/89 (44%) Frame = +1 Query: 940 AALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG 1119 AALNG + V+ L+ ED + D +G T LHYA+ G+ CQ L+ G Sbjct: 38 AALNGDLGRVKHLIQKA--------EDPSQPD--SAGYTALHYASRNGHYAVCQFLLESG 87 Query: 1120 ANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 A A+ G+T L A I +L Sbjct: 88 AKCDAQTHGGATALHRASYCGHTEIARLL 116
>Q8CGB3:UACA_MOUSE Uveal autoantigen with coiled-coil domains and ankyrin repeats - Mus| musculus (Mouse) Length = 1411 Score = 61.2 bits (147), Expect = 2e-08 Identities = 61/223 (27%), Positives = 95/223 (42%), Gaps = 2/223 (0%) Frame = +1 Query: 550 AAAQGHHEIVS-LLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYL 726 AA +G E VS +L + GV + G++A G+ E + ++ ++ D Sbjct: 43 AAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVASKGNLECLNAILTHGIDVATRDSA 102 Query: 727 NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNW 906 G A+H AA +GHA CL+ +L P T+H + Sbjct: 103 -GRNALHLAAKYGHALCLQKLLQYNCP--------TEHVDLQ------------------ 135 Query: 907 KADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN 1086 G T LH A + +QLL D GASV+ I+ G TPL A Sbjct: 136 ----GRTALHDAVMADCPSSIQLLCDHGASVNAKDID----------GRTPLVLATQMCR 181 Query: 1087 AVCCQLLIARGANLAAKNASGSTPLMVAHSWH-RNSIEEILSN 1212 CQLLI RGA++ +++ T LM+ + R+++E ++ N Sbjct: 182 PTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVKN 224 Score = 50.8 bits (120), Expect = 2e-05 Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 1/190 (0%) Frame = +1 Query: 640 LMQACQYGHWEVVQTLMLFNANIHRTDY-LNGGTAIHFAALHGHARCLRLVLADYVPSIP 816 LM+A + G E V ++ L +H + G +A H A G+ CL +L + Sbjct: 40 LMKAAERGDVEKVSSI-LAKKGVHPGKLDVEGRSAFHVVASKGNLECLNAILTHGI---- 94 Query: 817 NFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGAS 996 +V+ D G LH+AA GH C+Q LL Sbjct: 95 ------------DVATRD--------------SAGRNALHLAAKYGHALCLQKLLQYNCP 128 Query: 997 VSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHS 1176 V ++ G T LH A QLL GA++ AK+ G TPL++A Sbjct: 129 TEHVDLQ----------GRTALHDAVMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQ 178 Query: 1177 WHRNSIEEIL 1206 R +I ++L Sbjct: 179 MCRPTICQLL 188 Score = 41.2 bits (95), Expect = 0.018 Identities = 25/85 (29%), Positives = 45/85 (52%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PL A I LL++ G ++N R+ + +TALM C+YG + V+ L+ A++ Sbjct: 171 TPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVKNGADLTL 230 Query: 715 TDYLNGGTAIHFAALHGHARCLRLV 789 D L G + ++A + + L L+ Sbjct: 231 LDAL-GHDSSYYARIGDNLDILNLL 254
>Q7TQP6:TNI3K_RAT Serine/threonine-protein kinase TNNI3K - Rattus norvegicus (Rat)| Length = 835 Score = 61.2 bits (147), Expect = 2e-08 Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 10/201 (4%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESG--VEINLR 618 AA G Q LL++ + G R PLH A+A+G IV LL+E G ++N + Sbjct: 174 AAYYGHEQVTSVLLKFGADVNVSGEVGDR--PLHLASAKGFFNIVKLLVEEGSKADVNAQ 231 Query: 619 NYRGQTALMQACQYGHWEVVQTLMLFNANIH-RTDYLNGGTAIHFAALHGHARCLR-LVL 792 + L ++GH +V L+ + + + G T +H A +G+ + +V Sbjct: 232 DNEDHVPLHFCSRFGHHNIVSYLLQSDLEVQPHVINIYGDTPLHLACYNGNFEVAKEIVQ 291 Query: 793 ADYVPSIP--NFLNQTKHRSS----EEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNG 954 S+ N ++T S+ + + F D +N + G T LH A +G Sbjct: 292 VTGTESLTKENIFSETAFHSACTYGKNIDLVKFLLDQNAVNINHRGRDGHTGLHSACYHG 351 Query: 955 HVECVQLLLDLGASVSEVTIE 1017 H+ VQ LLD GA ++ V + Sbjct: 352 HIRLVQFLLDNGADMNLVACD 372 Score = 59.7 bits (143), Expect = 5e-08 Identities = 73/261 (27%), Positives = 106/261 (40%), Gaps = 17/261 (6%) Frame = +1 Query: 457 GDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQT 636 G+ RAL+ R +R + G LH A + E+++ LL SG ++ Y G T Sbjct: 79 GNKSHIRALMLKGLRPSRLTRNGF--PALHLAVYKDSPELITSLLHSGADVQQVGYGGLT 136 Query: 637 ALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL---AD--- 798 AL A GH E + L+ AN++ D + T +H AA +GH + ++L AD Sbjct: 137 ALHIAAIAGHPEAAEVLLQHGANVNVQDAV-FFTPLHIAAYYGHEQVTSVLLKFGADVNV 195 Query: 799 ---------YVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALN 951 ++ S F N K EE S AD VN + + PLH + Sbjct: 196 SGEVGDRPLHLASAKGFFNIVK-LLVEEGSKAD---------VNAQDNEDHVPLHFCSRF 245 Query: 952 GHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN-AVCCQLLIARGA-N 1125 GH V LL V I G TPLH A GN V +++ G + Sbjct: 246 GHHNIVSYLLQSDLEVQPHVINI--------YGDTPLHLACYNGNFEVAKEIVQVTGTES 297 Query: 1126 LAAKNASGSTPLMVAHSWHRN 1188 L +N T A ++ +N Sbjct: 298 LTKENIFSETAFHSACTYGKN 318 Score = 43.1 bits (100), Expect = 0.005 Identities = 28/96 (29%), Positives = 42/96 (43%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 G LH+A E + LL GA V +V G T LH AA G+ Sbjct: 101 GFPALHLAVYKDSPELITSLLHSGADVQQVGY----------GGLTALHIAAIAGHPEAA 150 Query: 1099 QLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 ++L+ GAN+ ++A TPL +A + + +L Sbjct: 151 EVLLQHGANVNVQDAVFFTPLHIAAYYGHEQVTSVL 186
>O14974:MYPT1_HUMAN Protein phosphatase 1 regulatory subunit 12A - Homo sapiens (Human)| Length = 1030 Score = 61.2 bits (147), Expect = 2e-08 Identities = 67/254 (26%), Positives = 105/254 (41%), Gaps = 36/254 (14%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 A + G + V LL G +IN N G TAL QAC + ++V+ L+ ANI++ D N Sbjct: 47 ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPD--N 104 Query: 730 GGTAIHFAALHGHARCLRLVLADYV-----------------------PSIPNFLNQTKH 840 G + LH A C L +A+++ ++ L + Sbjct: 105 EG----WIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVN 160 Query: 841 RSSEEVSDADFDDD-------------GLVKMVNWKADGGLTPLHMAALNGHVECVQLLL 981 R ++ A +++ G + V GG T LH+AA G+ E ++LL+ Sbjct: 161 RQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGG-TALHVAAAKGYTEVLKLLI 219 Query: 982 DLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL 1161 G +V I+D G TPLH AA G C++L+ ++ N G T Sbjct: 220 QAGY---DVNIKDY-------DGWTPLHAAAHWGKEEACRILVDNLCDMEMVNKVGQTAF 269 Query: 1162 MVAHSWHRNSIEEI 1203 VA +EE+ Sbjct: 270 DVADEDILGYLEEL 283
>Q8R560:ANKR1_RAT Ankyrin repeat domain-containing protein 1 - Rattus norvegicus (Rat)| Length = 319 Score = 61.2 bits (147), Expect = 2e-08 Identities = 54/187 (28%), Positives = 79/187 (42%) Frame = +1 Query: 631 QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPS 810 +TAL +AC GH +V+ LM A I D L TAIH+A G+ L+L+L Sbjct: 154 RTALHRACLEGHLAIVEKLMEAGAQIEFRDMLES-TAIHWACRGGNLDVLKLLL------ 206 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 ++S D K+++ T LH+A GH EC + L+ Sbjct: 207 ----------NKGAKISARD-------KLLS-------TALHVAVRTGHYECAEHLIACE 242 Query: 991 ASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 A ++ E G TPLH A +LL+ GA+L KN +G TP+ + Sbjct: 243 ADLNAKDRE----------GDTPLHDAVRLNRYKMIRLLMTFGADLNVKNCAGKTPMDLV 292 Query: 1171 HSWHRNS 1191 W + Sbjct: 293 LHWQNGT 299 Score = 59.7 bits (143), Expect = 5e-08 Identities = 48/171 (28%), Positives = 75/171 (43%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + + LH A +GH IV L+E+G +I R+ TA+ AC+ G+ +V++ L+ A I Sbjct: 153 KRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNLDVLKLLLNKGAKI 212 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 D L TA+H A GH C ++A +AD Sbjct: 213 SARDKLL-STALHVAVRTGHYECAEHLIA---------------------CEAD------ 244 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL 1041 +N K G TPLH A + ++LL+ GA ++ T +DL+ Sbjct: 245 ---LNAKDREGDTPLHDAVRLNRYKMIRLLMTFGADLNVKNCAGKTPMDLV 292 Score = 47.0 bits (110), Expect = 3e-04 Identities = 31/110 (28%), Positives = 56/110 (50%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 L EA A +E+ L ++ +H+A G+ +++ LLL G +I+ R+ TAL Sbjct: 172 LMEAGAQIEFRDML--------ESTAIHWACRGGNLDVLKLLLNKGAKISARDKLLSTAL 223 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 A + GH+E + L+ A+++ D G T +H A + +RL++ Sbjct: 224 HVAVRTGHYECAEHLIACEADLNAKD-REGDTPLHDAVRLNRYKMIRLLM 272 Score = 45.1 bits (105), Expect = 0.001 Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 23/117 (19%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTID-------------LLGSG----- 1050 T LH A L GH+ V+ L++ GA + + + T I LL G Sbjct: 155 TALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNLDVLKLLLNKGAKISA 214 Query: 1051 -----STPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 ST LH A G+ C + LIA A+L AK+ G TPL A +R + +L Sbjct: 215 RDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLL 271
>Q0P5B9:ANR39_BOVIN Ankyrin repeat domain-containing protein 39 - Bos taurus (Bovine)| Length = 183 Score = 60.8 bits (146), Expect = 2e-08 Identities = 38/117 (32%), Positives = 63/117 (53%) Frame = +1 Query: 442 SAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 SAA +GDL + L++ ++ + G + LHYA+ GH+ + LLESG + + + Sbjct: 37 SAALNGDLGRVKYLIQKAVDPSQPDSAG--YTALHYASRNGHYAVCQFLLESGAKCDAQT 94 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G TAL +A GH ++ + L+ +N D +G T++H AA GH L+L Sbjct: 95 HGGATALHRASYCGHTDIARLLLSHGSNPRLVD-ADGMTSLHKAAEKGHVDICSLLL 150 Score = 51.2 bits (121), Expect = 2e-05 Identities = 45/153 (29%), Positives = 64/153 (41%) Frame = +1 Query: 550 AAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLN 729 AA G V L++ V+ + + G TAL A + GH+ V Q L+ A + Sbjct: 38 AALNGDLGRVKYLIQKAVDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTH-G 96 Query: 730 GGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWK 909 G TA+H A+ GH RL+L+ H S+ + DAD Sbjct: 97 GATALHRASYCGHTDIARLLLS--------------HGSNPRLVDAD------------- 129 Query: 910 ADGGLTPLHMAALNGHVECVQLLLDLGASVSEV 1008 G+T LH AA GHV+ LLL ++ V Sbjct: 130 ---GMTSLHKAAEKGHVDICSLLLQHSPALKAV 159 Score = 44.7 bits (104), Expect = 0.002 Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 8/122 (6%) Frame = +1 Query: 877 DDGLVKMVNWKA-------DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTID 1035 D G VK + KA G T LH A+ NGH Q LL+ GA T Sbjct: 43 DLGRVKYLIQKAVDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQT-------- 94 Query: 1036 LLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILSN 1212 G+T LH A+ G+ +LL++ G+N +A G T L A H + +L + Sbjct: 95 --HGGATALHRASYCGHTDIARLLLSHGSNPRLVDADGMTSLHKAAEKGHVDICSLLLQH 152 Query: 1213 EP 1218 P Sbjct: 153 SP 154 Score = 37.4 bits (85), Expect = 0.26 Identities = 27/89 (30%), Positives = 38/89 (42%) Frame = +1 Query: 940 AALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG 1119 AALNG + V+ L+ S+ +G T LHYA+ G+ CQ L+ G Sbjct: 38 AALNGDLGRVKYLIQKAVDPSQPD----------SAGYTALHYASRNGHYAVCQFLLESG 87 Query: 1120 ANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 A A+ G+T L A I +L Sbjct: 88 AKCDAQTHGGATALHRASYCGHTDIARLL 116 Score = 36.6 bits (83), Expect = 0.44 Identities = 25/73 (34%), Positives = 33/73 (45%) Frame = +1 Query: 916 GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVC 1095 GG T LH A+ GH + +LLL G++ V + G T LH AA G+ Sbjct: 96 GGATALHRASYCGHTDIARLLLSHGSNPRLVDAD----------GMTSLHKAAEKGHVDI 145 Query: 1096 CQLLIARGANLAA 1134 C LL+ L A Sbjct: 146 CSLLLQHSPALKA 158
>Q9NXR5:ANR10_HUMAN Ankyrin repeat domain-containing protein 10 - Homo sapiens (Human)| Length = 420 Score = 60.8 bits (146), Expect = 2e-08 Identities = 51/182 (28%), Positives = 79/182 (43%), Gaps = 3/182 (1%) Frame = +1 Query: 640 LMQACQYGHWEVVQTLMLFNANIHRT--DYLNGGTAIHFAALHGHARCL-RLVLADYVPS 810 L +AC+ G + +L+ + H D G T +H+AA G CL +LV A Sbjct: 26 LHRACRDGDLATLCSLLQQTPHAHLASEDSFYGWTPVHWAAHFGKLECLVQLVRAGAT-- 83 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 LN + R ++ TP H+AA GH +C+ L+ G Sbjct: 84 ----LNVSTTRYAQ------------------------TPAHIAAFGGHPQCLVWLIQAG 115 Query: 991 ASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 A++++ E G TP+H AA G+ C L+A GA++ +NASG T +A Sbjct: 116 ANINKPDCE----------GETPIHKAARSGSLECISALVANGAHVDLRNASGLTAADIA 165 Query: 1171 HS 1176 + Sbjct: 166 QT 167 Score = 42.7 bits (99), Expect = 0.006 Identities = 30/110 (27%), Positives = 51/110 (46%) Frame = +1 Query: 463 LQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTAL 642 +Q RA N RY+ +P H AA GH + + L+++G IN + G+T + Sbjct: 75 VQLVRAGATLNVSTTRYA-----QTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPI 129 Query: 643 MQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 +A + G E + L+ A++ + +G TA A G C + +L Sbjct: 130 HKAARSGSLECISALVANGAHVDLRN-ASGLTAADIAQTQGFQECAQSLL 178 Score = 42.4 bits (98), Expect = 0.008 Identities = 61/253 (24%), Positives = 90/253 (35%), Gaps = 12/253 (4%) Frame = +1 Query: 388 LSLVGNSFGCSA--SGERLVS-------AARDGDLQEARALLEYNPR--LARYSTFGGRN 534 +S G G A S E L+S A RDGDL +LL+ P LA +F G Sbjct: 1 MSAAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLATLCSLLQQTPHAHLASEDSFYGW- 59 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +P+H+AA G E + L+ +G +N+ R Sbjct: 60 TPVHWAAHFGKLECLVQLVRAGATLNVSTTR----------------------------- 90 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 T H AA GH +CL ++ ++ ++ D + Sbjct: 91 ----YAQTPAHIAAFGGHPQCLVWLI----------------QAGANINKPDCE------ 124 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLL-GSGSTPLHYA 1071 G TP+H AA +G +EC+ L + +G +DL SG T A Sbjct: 125 --------GETPIHKAARSGSLECISAL-----------VANGAHVDLRNASGLTAADIA 165 Query: 1072 ACGGNAVCCQLLI 1110 G C Q L+ Sbjct: 166 QTQGFQECAQSLL 178 Score = 41.2 bits (95), Expect = 0.018 Identities = 24/67 (35%), Positives = 34/67 (50%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +P+H AA G E +S L+ +G ++LRN G TA A G E Q+L+ N H Sbjct: 127 TPIHKAARSGSLECISALVANGAHVDLRNASGLTAADIAQTQGFQECAQSLLNLQ-NCHL 185 Query: 715 TDYLNGG 735 + N G Sbjct: 186 NHFYNNG 192
>Q95N27:PP16B_BOVIN Protein phosphatase 1 regulatory inhibitor subunit 16B - Bos taurus| (Bovine) Length = 568 Score = 60.5 bits (145), Expect = 3e-08 Identities = 59/244 (24%), Positives = 101/244 (41%), Gaps = 2/244 (0%) Frame = +1 Query: 436 LVSAARDGDLQEARALLE--YNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 L+ A+ D +E R L+ +P L + LH EIV LLL G + Sbjct: 72 LLEASLRNDAEEVRYFLKNKVSPDLCNEDGL----TALHQCCIDNFEEIVKLLLSHGANV 127 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 N ++ T L A GH +V+ L+ + A++ + +G + Sbjct: 128 NAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNS-DGNMPYDLCEDEPTLDVIETC 186 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 +A Y +N+ + +++ + ++W G T LH+A NG++ Sbjct: 187 MA-YQGITQEKINEMRAAPEQQMISDIHCMIAAGQDLDWVDAQGATLLHIAGANGYLRAA 245 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 +LLLD G V ++D G PLH AA G +LL++ GA+L+A+ + Sbjct: 246 ELLLDHGV---RVDVKD-------WDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMD 295 Query: 1150 STPL 1161 P+ Sbjct: 296 EMPI 299 Score = 43.1 bits (100), Expect = 0.005 Identities = 48/196 (24%), Positives = 74/196 (37%), Gaps = 28/196 (14%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN----- 699 +PLH AA GH +V +L++ G ++ N G +V++T M + Sbjct: 136 TPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGITQE 195 Query: 700 --------------ANIH-------RTDYLN--GGTAIHFAALHGHARCLRLVLADYVPS 810 ++IH D+++ G T +H A +G+ R L+L Sbjct: 196 KINEMRAAPEQQMISDIHCMIAAGQDLDWVDAQGATLLHIAGANGYLRAAELLL------ 249 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 H +V D D G PLH AA G ++ +LL+ G Sbjct: 250 --------DHGVRVDVKDWD----------------GWEPLHAAAFWGQMQMAELLVSHG 285 Query: 991 ASVSEVTIEDGTTIDL 1038 AS+S T D IDL Sbjct: 286 ASLSARTSMDEMPIDL 301
>Q9J569:V162_FOWPV Putative ankyrin repeat protein FPV162 - Fowlpox virus (FPV)| Length = 603 Score = 60.1 bits (144), Expect = 4e-08 Identities = 65/244 (26%), Positives = 111/244 (45%), Gaps = 12/244 (4%) Frame = +1 Query: 475 RALLEYNPRLARYSTFGGRNSPLHYAAAQGH-HEIVSLLLESGVEINLRNYRGQTAL-MQ 648 R L+EY + N+PL AA + ++ + L+E G ++ ++N G T L + Sbjct: 144 RILVEYGANVNALDN--KHNTPLALAAELSNTNKTIETLIELGADVKIKNNDGITPLHLA 201 Query: 649 ACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSI--PNF 822 A + V+TL+L A+++ T G T +H AA +L +Y + N Sbjct: 202 AKSSSDSKTVETLILHGADVNAT-CSEGNTPLHDAATSYELSNTIEMLIEYGAEVNAANS 260 Query: 823 LNQTK-HRSSEEVSDADFDDDGLVKMVNWKADGGL--TPLHMAALNGHV-ECVQLLLDLG 990 + T H ++ + + N A G+ TPLH+A + + E +++L++ G Sbjct: 261 VGDTPLHCAARSRNPVHKLKTLIAHGSNVNAVNGISVTPLHLATYSDNATEALKVLIEHG 320 Query: 991 ASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNA----VCCQLLIARGANLAAKNASGSTP 1158 A V+ V I G TP+HY + ++ +LL+ GA++ AKN G TP Sbjct: 321 AEVNSVDIY----------GRTPMHYISRSYSSQSLKTAVELLVEHGADIEAKNVIGGTP 370 Query: 1159 LMVA 1170 L A Sbjct: 371 LSSA 374 Score = 57.0 bits (136), Expect = 3e-07 Identities = 64/223 (28%), Positives = 100/223 (44%), Gaps = 10/223 (4%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQY--GHWEVVQTLMLFNAN 705 ++PLHYA + E LL+ G + N + GQT L A E+V+ L+ + AN Sbjct: 93 STPLHYAVQENGLEATKKLLDLGADPNTKYMNGQTPLHCAAMVIPDGPELVRILVEYGAN 152 Query: 706 IHRTDYLNGGTAIHFAALHGHARCLRLVL---ADYVPSIPNFLNQTK-HRSSEEVSDADF 873 ++ D + A L + + ++ AD I N T H +++ SD+ Sbjct: 153 VNALDNKHNTPLALAAELSNTNKTIETLIELGADV--KIKNNDGITPLHLAAKSSSDSKT 210 Query: 874 DDDGLV--KMVNWKADGGLTPLHMAALNGHV-ECVQLLLDLGASVSEVTIEDGTTIDLLG 1044 + ++ VN G TPLH AA + + +++L++ GA V+ Sbjct: 211 VETLILHGADVNATCSEGNTPLHDAATSYELSNTIEMLIEYGAEVNAAN----------S 260 Query: 1045 SGSTPLHYAACGGNAV-CCQLLIARGANLAAKNASGSTPLMVA 1170 G TPLH AA N V + LIA G+N+ A N TPL +A Sbjct: 261 VGDTPLHCAARSRNPVHKLKTLIAHGSNVNAVNGISVTPLHLA 303
>Q8VHQ3:PP16B_MOUSE Protein phosphatase 1 regulatory inhibitor subunit 16B - Mus musculus| (Mouse) Length = 568 Score = 60.1 bits (144), Expect = 4e-08 Identities = 59/244 (24%), Positives = 101/244 (41%), Gaps = 2/244 (0%) Frame = +1 Query: 436 LVSAARDGDLQEARALLE--YNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 L+ A+ D +E R L+ +P L + LH EIV LLL G + Sbjct: 72 LLEASLRNDAEEVRYFLKNKVSPDLCNEDGL----TALHQCCIDNFEEIVKLLLSHGANV 127 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 N ++ T L A GH +V+ L+ + A++ + +G + Sbjct: 128 NAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNS-DGNMPYDLCEDEPTLDVIETC 186 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 +A Y +N+ + +++ + ++W G T LH+A NG++ Sbjct: 187 MA-YQGITQEKINEMRAAPEQKMISDIHCMIAAGQDLDWIDGQGATLLHIAGANGYLRAA 245 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 +LLLD G V ++D G PLH AA G +LL++ GA+L+A+ + Sbjct: 246 ELLLDHGV---RVDVKD-------WDGWEPLHAAAFWGQMPMAELLVSHGASLSARTSMD 295 Query: 1150 STPL 1161 P+ Sbjct: 296 EMPI 299 Score = 42.4 bits (98), Expect = 0.008 Identities = 48/196 (24%), Positives = 73/196 (37%), Gaps = 28/196 (14%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN----- 699 +PLH AA GH +V +L++ G ++ N G +V++T M + Sbjct: 136 TPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGITQE 195 Query: 700 --------------ANIH-------RTDYLNG--GTAIHFAALHGHARCLRLVLADYVPS 810 ++IH D+++G T +H A +G+ R L+L Sbjct: 196 KINEMRAAPEQKMISDIHCMIAAGQDLDWIDGQGATLLHIAGANGYLRAAELLL------ 249 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 H +V D D G PLH AA G + +LL+ G Sbjct: 250 --------DHGVRVDVKDWD----------------GWEPLHAAAFWGQMPMAELLVSHG 285 Query: 991 ASVSEVTIEDGTTIDL 1038 AS+S T D IDL Sbjct: 286 ASLSARTSMDEMPIDL 301
>Q9J5G9:V034_FOWPV Putative ankyrin repeat protein FPV034 - Fowlpox virus (FPV)| Length = 415 Score = 59.7 bits (143), Expect = 5e-08 Identities = 56/214 (26%), Positives = 99/214 (46%), Gaps = 7/214 (3%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A + +++ LL G+ IN+++ +G TAL ++++V L+ NA+I Sbjct: 111 LHSAITHENKKMIELLCLHGININVKDDKGYTALYYTICNNNYDMVCFLLEKNADI---S 167 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 +N + +HF + + VL D + N +N K V + G + ++ Sbjct: 168 IVNKYSMLHFLSTSNKYHNVMAVLLDKGIDV-NIINHVKAPIHVAVERNNIY--GTMLLI 224 Query: 901 NWKAD-------GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTP 1059 N AD GG T LH+A + E +L++ GA+V + +D G+TP Sbjct: 225 NRNADVNIKELHGGRTSLHLAIKERNYEAAFVLINNGANVD--SFDD--------VGNTP 274 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPL 1161 + AA + +LL+ GA++ +N G TP+ Sbjct: 275 IFIAASLQDVRFMKLLLDNGADINVRNVFGETPV 308 Score = 42.0 bits (97), Expect = 0.010 Identities = 47/246 (19%), Positives = 85/246 (34%), Gaps = 21/246 (8%) Frame = +1 Query: 475 RALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQAC 654 R +L + Y F + L A H +V++ ++ IN+ + G T L A Sbjct: 30 RMILNQQENINTYKHF----NMLRKAVLNHDHNLVNIFIDKNFNINIADSVGYTLLRYAV 85 Query: 655 QYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQT 834 + + + L+ + I++ DY +H A H + + + L+ + Sbjct: 86 EVDDVNIAKILLDAGSIINKNDY----RLLHSAITHENKKMIELLCLHGI---------- 131 Query: 835 KHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVS---- 1002 +N K D G T L+ N + + V LL+ A +S Sbjct: 132 --------------------NINVKDDKGYTALYYTICNNNYDMVCFLLEKNADISIVNK 171 Query: 1003 -----------------EVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLA 1131 V ++ G ++++ P+H A N LLI R A++ Sbjct: 172 YSMLHFLSTSNKYHNVMAVLLDKGIDVNIINHVKAPIHVAVERNNIYGTMLLINRNADVN 231 Query: 1132 AKNASG 1149 K G Sbjct: 232 IKELHG 237 Score = 35.8 bits (81), Expect = 0.74 Identities = 22/79 (27%), Positives = 39/79 (49%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A ++ + + A L+ + + G N+P+ AA+ + LLL++G +IN+RN Sbjct: 245 AIKERNYEAAFVLINNGANVDSFDDVG--NTPIFIAASLQDVRFMKLLLDNGADINVRNV 302 Query: 625 RGQTALMQACQYGHWEVVQ 681 G+T + G EV Q Sbjct: 303 FGETPVNMVITGGSKEVTQ 321
>Q9Y566:SHAN1_HUMAN SH3 and multiple ankyrin repeat domains protein 1 - Homo sapiens| (Human) Length = 2161 Score = 59.7 bits (143), Expect = 5e-08 Identities = 69/248 (27%), Positives = 106/248 (42%), Gaps = 10/248 (4%) Frame = +1 Query: 499 RLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY-RGQTALMQACQY-GHWE 672 +LA+ T G L Y G + V+ LL+ G++ N + G+T L A Q G E Sbjct: 170 QLAKLHTKTGLKKFLEYVQL-GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVE 228 Query: 673 VVQTLMLFNANIHRTDYL--NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRS 846 V++TL L A+I D+ +G TA+H AA H CL L + PN+ ++ Sbjct: 229 VIRTLCLGGAHI---DFRARDGMTALHKAACARH--CLALTALLDLGGSPNYKDRRGLTP 283 Query: 847 SEEVSDADFDDDGLVKMVNWKA------DGGLTPLHMAALNGHVECVQLLLDLGASVSEV 1008 + D ++ +A + G +H A GH + ++ LL GA Sbjct: 284 LFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQ 343 Query: 1009 TIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRN 1188 SG+T LH A C ++L+ RGA+ KN +G TP VA Sbjct: 344 N----------ASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNF 393 Query: 1189 SIEEILSN 1212 + E++ N Sbjct: 394 ELGELIRN 401 Score = 46.2 bits (108), Expect = 6e-04 Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 4/114 (3%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL-HYAA 1074 ++++A G+T LH AA H + LLDLG S + G TPL H A Sbjct: 240 IDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKD----------RRGLTPLFHTAM 289 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEIL--SNEPGGQ 1227 GG+ CC+LL+ A L + +G + H +E +L EPG Q Sbjct: 290 VGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQ 343
>Q63369:NFKB1_RAT Nuclear factor NF-kappa-B p105 subunit - Rattus norvegicus (Rat)| Length = 522 Score = 59.7 bits (143), Expect = 5e-08 Identities = 71/280 (25%), Positives = 110/280 (39%), Gaps = 51/280 (18%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLE------SGVEINLRNYRGQTALMQACQYGHWEVVQTLML 693 +S LH A H ++V LLE S IN+RN QT L A +VV+ L+ Sbjct: 91 DSVLHLAIIHLHAQLVRDLLEVTSGSISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLR 150 Query: 694 FNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADF 873 A++ D G + +H AA GH + L ++L + ++ Sbjct: 151 VGADLSLLDRW-GNSVLHLAAKEGHDKILGVLLKNSKAAL-------------------- 189 Query: 874 DDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTT-------- 1029 ++N GL +H+A ++ + C+QLL+ GA V+ + G T Sbjct: 190 -------LINHPNGEGLNAIHIAVMSNSLSCLQLLVAAGAEVNAQEQKSGRTALHLAVEY 242 Query: 1030 --IDLLG---------------SGSTPLHYAACGGNAVCCQLLIARGANLAAKN------ 1140 I L G G+TPLH AA G+ LL A GA+ +N Sbjct: 243 DNISLAGCLLLEGDALVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYD 302 Query: 1141 --------------ASGSTPLMVAHSWHRNSIEEILSNEP 1218 G+TPL +A +W + +IL+ +P Sbjct: 303 LDDSWEKAGEDEGVVPGTTPLDMAANW---QVFDILNGKP 339 Score = 48.1 bits (113), Expect = 1e-04 Identities = 47/200 (23%), Positives = 78/200 (39%), Gaps = 27/200 (13%) Frame = +1 Query: 676 VQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEE 855 V+ L+ ++ NG + +H A +H HA+ +R +L E Sbjct: 72 VKMLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVRDLL--------------------E 111 Query: 856 VSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTID 1035 V+ DD ++N + D TPLH+A + + V+ LL +GA +S + + + Sbjct: 112 VTSGSISDD----IINMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVLH 167 Query: 1036 LL--------------------------GSGSTPLHYAACGGNAVCCQLLIARGANL-AA 1134 L G G +H A + C QLL+A GA + A Sbjct: 168 LAAKEGHDKILGVLLKNSKAALLINHPNGEGLNAIHIAVMSNSLSCLQLLVAAGAEVNAQ 227 Query: 1135 KNASGSTPLMVAHSWHRNSI 1194 + SG T L +A + S+ Sbjct: 228 EQKSGRTALHLAVEYDNISL 247
>P25799:NFKB1_MOUSE Nuclear factor NF-kappa-B p105 subunit - Mus musculus (Mouse)| Length = 971 Score = 59.7 bits (143), Expect = 5e-08 Identities = 74/278 (26%), Positives = 108/278 (38%), Gaps = 27/278 (9%) Frame = +1 Query: 466 QEARALLEYNPRLARYSTFGGRN----SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQ 633 Q R LLE L RN +PLH A ++V LL G +++L + G Sbjct: 553 QLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGN 612 Query: 634 TALMQACQYGHWEVVQTLMLFNANIHRTDYLNGG--TAIHFAALHGHARCLRLVLADYVP 807 + L A + GH ++ L+ D+ NG AIH A + CL L++A Sbjct: 613 SVLHLAAKEGHDRILSILLKSRKAAPLIDHPNGEGLNAIHIAVMSNSLPCLLLLVA---- 668 Query: 808 SIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQ-LLLD 984 + EV+ + G TPLH+A ++ LLL+ Sbjct: 669 ------------AGAEVNAQE-------------QKSGRTPLHLAVEYDNISLAGCLLLE 703 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKN-------- 1140 A V D TT D G+TPLH AA G+ LL A GA+ +N Sbjct: 704 GDAHV------DSTTYD----GTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLD 753 Query: 1141 ------------ASGSTPLMVAHSWHRNSIEEILSNEP 1218 G+TPL +A +W + +IL+ +P Sbjct: 754 DSWEKAGEDEGVVPGTTPLDMAANW---QVFDILNGKP 788 Score = 47.0 bits (110), Expect = 3e-04 Identities = 47/200 (23%), Positives = 78/200 (39%), Gaps = 27/200 (13%) Frame = +1 Query: 676 VQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEE 855 V+ L+ ++ NG + +H A +H HA+ +R +L E Sbjct: 521 VKMLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVRDLL--------------------E 560 Query: 856 VSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTID 1035 V+ DD ++N + D TPLH+A + + V+ LL +GA +S + + + Sbjct: 561 VTSGLISDD----IINMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVLH 616 Query: 1036 LL--------------------------GSGSTPLHYAACGGNAVCCQLLIARGANL-AA 1134 L G G +H A + C LL+A GA + A Sbjct: 617 LAAKEGHDRILSILLKSRKAAPLIDHPNGEGLNAIHIAVMSNSLPCLLLLVAAGAEVNAQ 676 Query: 1135 KNASGSTPLMVAHSWHRNSI 1194 + SG TPL +A + S+ Sbjct: 677 EQKSGRTPLHLAVEYDNISL 696
>Q04861:NFKB1_CHICK Nuclear factor NF-kappa-B p105 subunit [Contains: Nuclear factor| NF-kappa-B p50 subunit] - Gallus gallus (Chicken) Length = 984 Score = 59.7 bits (143), Expect = 5e-08 Identities = 80/313 (25%), Positives = 118/313 (37%), Gaps = 51/313 (16%) Frame = +1 Query: 433 RLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVE-- 606 RL A GD+ R LL L G N LH + H E+V LLE + Sbjct: 513 RLFDYAVTGDV---RMLLAVQRHLTAVQDDNGDNV-LHLSIIHLHRELVKNLLEVMPDMN 568 Query: 607 ----INLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHAR 774 IN+RN QT L A EVV+ L+ AN++ D +G + +H AA G + Sbjct: 569 YNNIINMRNDLYQTPLHLAVITKQAEVVEDLLKAGANVNLLDR-HGNSVLHLAAAEGDDK 627 Query: 775 CLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNG 954 L L+L KH+ + + D + GL+ +HM Sbjct: 628 ILSLLL--------------KHQKASSMIDLSNGE-------------GLSAIHMVVTAN 660 Query: 955 HVECVQLLLDLGASVSEVTIEDGTT----------IDLLG---------------SGSTP 1059 + C++LL+ G V+ + G T + L G G+TP Sbjct: 661 SLSCLKLLIAAGVDVNAQEQKSGRTALHLAVEQENVPLAGCLLLEGDADVDSTTYDGTTP 720 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKN--------------------ASGSTPLMVAHSW 1179 LH AA G +L A GA+ +N G+TPL +A +W Sbjct: 721 LHIAAGRGFTKLAAVLKAAGADPHVENFEPLFDVEEDVKDDDDDEGIVPGTTPLDMAANW 780 Query: 1180 HRNSIEEILSNEP 1218 + +IL+ +P Sbjct: 781 ---EVYDILNGKP 790
>Q06527:ANKH_CHRVI Ankyrin homolog precursor - Chromatium vinosum (Allochromatium| vinosum) Length = 323 Score = 59.7 bits (143), Expect = 5e-08 Identities = 73/256 (28%), Positives = 106/256 (41%) Frame = +1 Query: 403 NSFGCSASGERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVS 582 N FG +A L+ A DL+ LL + + G +PL +AA GH I + Sbjct: 62 NQFGKTA----LMFAVEGDDLETVALLLSRGADVNARTVAGC--TPLTFAAEAGHIGISA 115 Query: 583 LLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALH 762 LLLE G ++ R G ALM A ++G ++V+ L+ A+ D G TA+ AA Sbjct: 116 LLLERGAHVHDRTRSGWDALMIASRHGITDMVEQLLFKGADPKAAD-REGRTALMQAASK 174 Query: 763 GHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMA 942 G L L++ E +D + D G T L +A Sbjct: 175 GETGVLPLLI-------------------EGGADLEARD-----------KQGATALLIA 204 Query: 943 ALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGA 1122 A G V+ L LGA + +D L GST L A G+ + L+A GA Sbjct: 205 ADQGQAGAVETLAGLGAQLD--------AVDAL--GSTALILAVGHGHVAMVERLLAMGA 254 Query: 1123 NLAAKNASGSTPLMVA 1170 + ++ G+T LM A Sbjct: 255 DPNRQDRKGTTALMEA 270 Score = 47.0 bits (110), Expect = 3e-04 Identities = 64/216 (29%), Positives = 93/216 (43%), Gaps = 6/216 (2%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH-RT 717 L A G E + LL+ G ++ N G+TALM A + E V L+ A+++ RT Sbjct: 36 LRLNAMIGDTETAAELLDQGAHVDAPNQFGKTALMFAVEGDDLETVALLLSRGADVNART 95 Query: 718 DYLNGGTAIHFAALHGHARCLRLVL---ADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + G T + FAA GH L+L A + + S ++ D + L Sbjct: 96 --VAGCTPLTFAAEAGHIGISALLLERGAHVHDRTRSGWDALMIASRHGIT--DMVEQLL 151 Query: 889 VKMVNWKADG--GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPL 1062 K + KA G T L AA G + LL++ GA + + G+T L Sbjct: 152 FKGADPKAADREGRTALMQAASKGETGVLPLLIEGGADLEARDKQ----------GATAL 201 Query: 1063 HYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 AA G A + L GA L A +A GST L++A Sbjct: 202 LIAADQGQAGAVETLAGLGAQLDAVDALGSTALILA 237
>Q9WTK5:NFKB2_MOUSE Nuclear factor NF-kappa-B p100 subunit - Mus musculus (Mouse)| Length = 899 Score = 59.3 bits (142), Expect = 6e-08 Identities = 74/269 (27%), Positives = 107/269 (39%), Gaps = 34/269 (12%) Frame = +1 Query: 457 GDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLES-------GVEINL 615 G +ARALL L G ++PLH A G ++ + GV INL Sbjct: 465 GVTADARALLAGQRHLLMAQDENG-DTPLHLAIIHGQTGVIEQIAHVIYHAQYLGV-INL 522 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHA--RCLRLV 789 N+ QT L A G VV L+ A+ D +G +A+H A G A L+ + Sbjct: 523 TNHLHQTPLHLAVITGQTRVVSFLLQVGADPTLLDR-HGDSALHLALRAGAAAPELLQAL 581 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 L ++P L+ DF+ GL P+H+A EC+ Sbjct: 582 LRSGAHAVPQILHMP-----------DFE--------------GLYPVHLAVHARSPECL 616 Query: 970 QLLLDLGASVSEVTIEDGTT-------IDLLG------------------SGSTPLHYAA 1074 LL+D GA V + G T ++ LG +G+TPLH AA Sbjct: 617 DLLVDCGAEVEAPERQGGRTALHLATEMEELGLVTHLVTKLHANVNARTFAGNTPLHLAA 676 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGSTPL 1161 G+ +LL+ GA++ A+N PL Sbjct: 677 GLGSPTLTRLLLKAGADIHAENEEPLCPL 705
>Q9D2X0:ANR39_MOUSE Ankyrin repeat domain-containing protein 39 - Mus musculus (Mouse)| Length = 183 Score = 59.3 bits (142), Expect = 6e-08 Identities = 38/117 (32%), Positives = 62/117 (52%) Frame = +1 Query: 442 SAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 SAA +GDL + ++ ++ + G + LHYA+ GH+ + LLESG + + + Sbjct: 37 SAALNGDLGRVKYFIQKATDPSQPDSAG--YTALHYASRNGHYAVCQFLLESGAKCDAQT 94 Query: 622 YRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 + G TAL +A GH E+ + L+ +N D +G T++H AA GH L+L Sbjct: 95 HGGATALHRASYCGHTEIARLLLSHGSNPWLVDN-DGMTSLHKAAEKGHEDICSLLL 150 Score = 42.7 bits (99), Expect = 0.006 Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 1/101 (0%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 G T LH A+ NGH Q LL+ GA T G+T LH A+ G+ Sbjct: 64 GYTALHYASRNGHYAVCQFLLESGAKCDAQT----------HGGATALHRASYCGHTEIA 113 Query: 1099 QLLIARGANLAAKNASGSTPL-MVAHSWHRNSIEEILSNEP 1218 +LL++ G+N + G T L A H + +L + P Sbjct: 114 RLLLSHGSNPWLVDNDGMTSLHKAAEKGHEDICSLLLQHSP 154 Score = 36.2 bits (82), Expect = 0.57 Identities = 26/73 (35%), Positives = 32/73 (43%) Frame = +1 Query: 916 GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVC 1095 GG T LH A+ GH E +LLL G++ V G T LH AA G+ Sbjct: 96 GGATALHRASYCGHTEIARLLLSHGSNPWLVD----------NDGMTSLHKAAEKGHEDI 145 Query: 1096 CQLLIARGANLAA 1134 C LL+ L A Sbjct: 146 CSLLLQHSPALKA 158 Score = 35.8 bits (81), Expect = 0.74 Identities = 26/89 (29%), Positives = 37/89 (41%) Frame = +1 Query: 940 AALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARG 1119 AALNG + V+ + S+ +G T LHYA+ G+ CQ L+ G Sbjct: 38 AALNGDLGRVKYFIQKATDPSQPD----------SAGYTALHYASRNGHYAVCQFLLESG 87 Query: 1120 ANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 A A+ G+T L A I +L Sbjct: 88 AKCDAQTHGGATALHRASYCGHTEIARLL 116
>Q5GIG6:TNI3K_MOUSE Serine/threonine-protein kinase TNNI3K - Mus musculus (Mouse)| Length = 834 Score = 58.9 bits (141), Expect = 8e-08 Identities = 68/252 (26%), Positives = 103/252 (40%), Gaps = 8/252 (3%) Frame = +1 Query: 457 GDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQT 636 G+ RAL+ R +R + G LH A + E+++ LL SG ++ Y G T Sbjct: 79 GNKSHIRALMLKGLRPSRLTRNGF--PALHLAVYKDSLELITSLLHSGADVQQAGYGGLT 136 Query: 637 ALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIP 816 AL A GH E V+ L+ AN++ D + T +H AA +GH + ++L + Sbjct: 137 ALHIAAIAGHPEAVEVLLQHGANVNVQDAV-FFTPLHIAAYYGHEQVTSVLLK--FGADV 193 Query: 817 NFLNQTKHRSSEEVSDADFDD------DGLVKMVNWKADGGLTPLHMAALNGHVECVQLL 978 N + R S F + +G VN + + PLH + GH V L Sbjct: 194 NVSGEVGDRPLHLASAKGFFNIVKLLVEGNKADVNAQDNEDHVPLHFCSRFGHHNIVSYL 253 Query: 979 LDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGN-AVCCQLLIARGA-NLAAKNASGS 1152 L V I G TPLH A GN V +++ G +L +N Sbjct: 254 LQSDLEVQPHVINI--------YGDTPLHLACYNGNFEVAKEIVHVTGTESLTKENIFSE 305 Query: 1153 TPLMVAHSWHRN 1188 T A ++ +N Sbjct: 306 TAFHSACTYGKN 317 Score = 57.0 bits (136), Expect = 3e-07 Identities = 82/321 (25%), Positives = 133/321 (41%), Gaps = 63/321 (19%) Frame = +1 Query: 520 FGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN 699 +GG + LH AA GH E V +LL+ G +N+++ T L A YGH +V L+ F Sbjct: 132 YGGLTA-LHIAAIAGHPEAVEVLLQHGANVNVQDAVFFTPLHIAAYYGHEQVTSVLLKFG 190 Query: 700 ANIHRTDYLNGGTAIHFAALHGHARCLRLVL------------ADYVPSIPNFLNQTKHR 843 A+++ + + G +H A+ G ++L++ D+VP +F ++ H Sbjct: 191 ADVNVSGEV-GDRPLHLASAKGFFNIVKLLVEGNKADVNAQDNEDHVPL--HFCSRFGHH 247 Query: 844 SSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIED- 1020 + D + ++N D TPLH+A NG+ E + ++ + + S +T E+ Sbjct: 248 NIVSYL-LQSDLEVQPHVINIYGD---TPLHLACYNGNFEVAKEIVHVTGTES-LTKENI 302 Query: 1021 ------------GTTIDLL---------------GSGSTPLHYAACGGNAVCCQLLIARG 1119 G IDL+ G T LH A G+ Q L+ G Sbjct: 303 FSETAFHSACTYGKNIDLVKFLLDQNAVNINHRGRDGHTGLHSACYHGHIRLVQFLLDNG 362 Query: 1120 A--NLAAKNASGS-------TPLMVAHSWHRNSIEEILS--------------NEPGGQI 1230 A NL A + S S T LM A+ ++I +L ++PGG Sbjct: 363 ADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLKHYKRPQDELPCNEYSQPGGDG 422 Query: 1231 RTLPSPYLCLPLMSIMSIARE 1293 + P PL I S+ +E Sbjct: 423 SYVSVP---SPLGKIKSMTKE 440
>Q96T49:PP16B_HUMAN Protein phosphatase 1 regulatory inhibitor subunit 16B - Homo sapiens| (Human) Length = 567 Score = 58.9 bits (141), Expect = 8e-08 Identities = 59/244 (24%), Positives = 101/244 (41%), Gaps = 2/244 (0%) Frame = +1 Query: 436 LVSAARDGDLQEARALLE--YNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 L+ A+ D +E R L+ +P L + LH EIV LLL G + Sbjct: 72 LLEASLRNDAEEVRYFLKNKVSPDLCNEDGL----TALHQCCIDNFEEIVKLLLSHGANV 127 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLV 789 N ++ T L A GH +V+ L+ + A++ + +G + Sbjct: 128 NAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVN-SDGNMPYDLCEDEPTLDVIETC 186 Query: 790 LADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECV 969 +A Y +N+ + +++ + ++W G T LH+A NG++ Sbjct: 187 MA-YQGITQEKINEMRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAA 245 Query: 970 QLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 +LLLD G V ++D G PLH AA G +LL++ GA+L+A+ + Sbjct: 246 ELLLDHGV---RVDVKD-------WDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMD 295 Query: 1150 STPL 1161 P+ Sbjct: 296 EMPI 299 Score = 44.7 bits (104), Expect = 0.002 Identities = 49/196 (25%), Positives = 74/196 (37%), Gaps = 28/196 (14%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFN----- 699 +PLH AA GH +V +L++ G ++ N G +V++T M + Sbjct: 136 TPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGITQE 195 Query: 700 --------------ANIH-------RTDYLN--GGTAIHFAALHGHARCLRLVLADYVPS 810 A+IH D+++ G T +H A +G+ R L+L Sbjct: 196 KINEMRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLL------ 249 Query: 811 IPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLG 990 H +V D D G PLH AA G ++ +LL+ G Sbjct: 250 --------DHGVRVDVKDWD----------------GWEPLHAAAFWGQMQMAELLVSHG 285 Query: 991 ASVSEVTIEDGTTIDL 1038 AS+S T D IDL Sbjct: 286 ASLSARTSMDEMPIDL 301
>Q9J5A7:V155_FOWPV Putative ankyrin repeat protein FPV115 - Fowlpox virus (FPV)| Length = 542 Score = 58.5 bits (140), Expect = 1e-07 Identities = 58/206 (28%), Positives = 96/206 (46%), Gaps = 5/206 (2%) Frame = +1 Query: 571 EIVSLLLESGVEINLRNYRGQTALMQACQYGHW-EVVQTLMLFNANIHRTDYLNGGTAIH 747 +++ L+E G++IN ++ +G+TAL AC + E V+ +M + A+I+ D G T +H Sbjct: 233 DMLLFLIEIGLDINTKDKKGKTALHYACNSINCIETVKEIMKYGADINVKDR-EGLTPLH 291 Query: 748 FAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLT 927 A +G + +L++ +Y + T + E + + LVK + K +T Sbjct: 292 SACKYGDLKLSKLLI-EYGADVKVKTTSTVLNLAVESGNVE-----LVKFLIEKNPEFIT 345 Query: 928 P----LHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVC 1095 L +A + V LLLD G V+ STPLH GN+ Sbjct: 346 SDYLSLSLAIRCKDINIVLLLLDAGMDVNSSKCI-----------STPLHLGVILGNSNI 394 Query: 1096 CQLLIARGANLAAKNASGSTPLMVAH 1173 +LL+ GAN+ A + G TPL A+ Sbjct: 395 VKLLLDHGANINAIDKYGETPLEAAN 420 Score = 33.9 bits (76), Expect = 2.8 Identities = 29/119 (24%), Positives = 57/119 (47%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L SA + GDL+ ++ L+EY + +T ++ L+ A G+ E+V L+E E Sbjct: 290 LHSACKYGDLKLSKLLIEYGADVKVKTT----STVLNLAVESGNVELVKFLIEKNPEFIT 345 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVL 792 +Y +L C+ ++ L+L +A + T +H + G++ ++L+L Sbjct: 346 SDYL-SLSLAIRCK----DINIVLLLLDAGMDVNSSKCISTPLHLGVILGNSNIVKLLL 399
>Q9TXQ1:PME5_CAEEL Poly(ADP-ribose) polymerase pme-5 - Caenorhabditis elegans| Length = 2276 Score = 58.5 bits (140), Expect = 1e-07 Identities = 68/291 (23%), Positives = 118/291 (40%), Gaps = 59/291 (20%) Frame = +1 Query: 514 STFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML 693 ST R +PL A +G+ E+ L+E G + ++ + +T L+ A G L+ Sbjct: 494 STGQNRLTPLMMACGKGYLEMAKKLVEKGALVEGKDKKKRTPLIHAMLNGQIHTAAFLLA 553 Query: 694 FNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA--DYVPSIPN---------------- 819 A++ D +G TA H+AA +G CL+L+ + D + S PN Sbjct: 554 KGASLTLADS-SGNTAAHYAAAYGFLDCLKLLASIDDNILSEPNDWQLYPLSVAYLKGHY 612 Query: 820 ----FLNQTKHRSSEEVSDAD------------FDDDGLVK--------MVNWKADGGL- 924 +L + H+ ++ D + D+ + K +V KAD L Sbjct: 613 GIVTWLLEGPHKDKANINAKDNNGATLLSNLLSYADETMHKELLSQIEYLVARKADASLA 672 Query: 925 -----TPLHMAALNGHV----------ECVQLLLDLGASVSEVTIEDGTTIDLLG-SGST 1056 TPLH+ ++ + + +++ LD I+ G +D+ +T Sbjct: 673 DSSGQTPLHLFSMQRIILKGSGEAAENDAMRMTLDNYKKCFNTLIKAGAKVDVYDHEDNT 732 Query: 1057 PLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILS 1209 PLHYA GN + L++ + AN L + H+N + EIL+ Sbjct: 733 PLHYALTNGNLMLFNLMLDKVAN--------KRNLFEKWANHQNFLHEILA 775 Score = 39.7 bits (91), Expect = 0.051 Identities = 52/207 (25%), Positives = 90/207 (43%), Gaps = 2/207 (0%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 +HYAA + LL++G + + + +T L A + G LM ++ + D Sbjct: 383 MHYAACAPGTAPMEFLLKNGGSVTMLTKQTETPLHVAARAGRAVNCTFLMKEMLDLEKGD 442 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMV 900 +G + I R R ++ S + L+ R++ +V DA + +V + Sbjct: 443 --DGESTI---------RADRSIINARTRSGNSALHLAVLRNNLDVVDALLAEPTIV-VD 490 Query: 901 NWKADGG--LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAA 1074 N + G LTPL MA G++E + L++ GA V + TPL +A Sbjct: 491 NPTSTGQNRLTPLMMACGKGYLEMAKKLVEKGALVEGKDKKK----------RTPLIHAM 540 Query: 1075 CGGNAVCCQLLIARGANLAAKNASGST 1155 G L+A+GA+L ++SG+T Sbjct: 541 LNGQIHTAAFLLAKGASLTLADSSGNT 567 Score = 35.8 bits (81), Expect = 0.74 Identities = 18/49 (36%), Positives = 27/49 (55%) Frame = +1 Query: 1045 SGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNS 1191 +G+T LH AA + +C LI + ++ KN G+TPL +A R S Sbjct: 1171 NGNTILHLAAIKNSTICLMTLIRKKCHVDLKNKDGNTPLALAVHHGRQS 1219 Score = 33.1 bits (74), Expect = 4.8 Identities = 30/113 (26%), Positives = 49/113 (43%), Gaps = 6/113 (5%) Frame = +1 Query: 850 EEVSDADFDDDGLV------KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVT 1011 +E+ D + DDG ++N + G + LH+A L +++ V LL +E T Sbjct: 433 KEMLDLEKGDDGESTIRADRSIINARTRSGNSALHLAVLRNNLDVVDALL------AEPT 486 Query: 1012 IEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 I + TPL A G + L+ +GA + K+ TPL+ A Sbjct: 487 IVVDNPTSTGQNRLTPLMMACGKGYLEMAKKLVEKGALVEGKDKKKRTPLIHA 539
>Q9BZ19:CT086_HUMAN Ankyrin repeat-containing protein C20orf86 - Homo sapiens (Human)| Length = 240 Score = 58.5 bits (140), Expect = 1e-07 Identities = 49/174 (28%), Positives = 76/174 (43%), Gaps = 17/174 (9%) Frame = +1 Query: 703 NIHRTDYLNGGTAIHFAALHGH--------ARCL-------RLVLA--DYVPSIPNFLNQ 831 N+ R YL+ G + L H + C+ LVLA + PS + L Sbjct: 29 NLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAAVEGDPSKLSCLGL 88 Query: 832 TKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVT 1011 T+ + F+ + K +W + L++A+ GH + VQ LL+ GAS Sbjct: 89 TEDSFYRTANSEHFEGE---KWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASC---- 141 Query: 1012 IEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAH 1173 + G TPLH AA G + C LL+ GA++ ++A G TP+ +AH Sbjct: 142 ------LSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAH 189 Score = 40.8 bits (94), Expect = 0.023 Identities = 25/77 (32%), Positives = 38/77 (49%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINL 615 L A+ G + LLE+ S G +PLH AAA G + + LLL+ G I+ Sbjct: 119 LYVASHRGHFDAVQYLLEHGASCLSRSPLG--RTPLHVAAAMGRSDCIILLLQHGASIHD 176 Query: 616 RNYRGQTALMQACQYGH 666 R+ +G+T + A + H Sbjct: 177 RDAKGETPISIAHRLNH 193 Score = 35.8 bits (81), Expect = 0.74 Identities = 25/76 (32%), Positives = 35/76 (46%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 L+ A+ +GH + V LLE G R+ G+T L A G + + L+ A+IH D Sbjct: 119 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 178 Query: 721 YLNGGTAIHFAALHGH 768 G T I A H Sbjct: 179 -AKGETPISIAHRLNH 193
>Q810B6:ANFY1_MOUSE Ankyrin repeat and FYVE domain-containing protein 1 - Mus musculus| (Mouse) Length = 1169 Score = 58.5 bits (140), Expect = 1e-07 Identities = 63/235 (26%), Positives = 105/235 (44%), Gaps = 10/235 (4%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH- 711 +PLH AA+ G E V LLE G +N ++ G+T + A H ++Q L++ + NI Sbjct: 772 TPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPVHVAISNQHSVIIQ-LLISHPNIEL 830 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 G T A + + + +L + N K R+ V+ + D + ++ Sbjct: 831 SVRDRQGLTPFACAMTYKNNKAAEAILKRESGAAEQVDN--KGRNFLHVAVQNSDIESVL 888 Query: 892 KMVNWKAD--------GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS 1047 +++ +A+ LTPLH+A G V+ LL GA V+E+T Sbjct: 889 FLISVQANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELT----------KH 938 Query: 1048 GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHR-NSIEEILS 1209 T LH AA C +L+ G + AA + +G+ L +A R N+I +L+ Sbjct: 939 RQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRALLT 993 Score = 57.0 bits (136), Expect = 3e-07 Identities = 67/249 (26%), Positives = 102/249 (40%), Gaps = 22/249 (8%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A + + LLE +IN+R G+TAL A ++ VV + A++ D Sbjct: 626 LHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKHQLPLVVDAICTRGADMSVPD 685 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYV-------PSIPNFLNQTKHRSSEEVSDADFD- 876 G + AL + + L + P L HR+ +E +++ Sbjct: 686 --EKGNPPLWLALASNLEDIASTLVRHGCDATCWGPGPSGCLQTLLHRAVDENNESTACF 743 Query: 877 ------DDGLVKMVNWKADG------GLTPLHMAALNGHVECVQLLLDLGASVSEVTIED 1020 D + +G G TPLH+AA G E VQ LL+ GA+V+ E Sbjct: 744 LIRSGCDVNSPRQPGTNGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAE- 802 Query: 1021 GTTIDLLGSGSTPLHYAACGGNAVCCQLLIAR-GANLAAKNASGSTPLMVAHSWHRN-SI 1194 G TP+H A ++V QLLI+ L+ ++ G TP A ++ N + Sbjct: 803 ---------GRTPVHVAISNQHSVIIQLLISHPNIELSVRDRQGLTPFACAMTYKNNKAA 853 Query: 1195 EEILSNEPG 1221 E IL E G Sbjct: 854 EAILKRESG 862 Score = 54.7 bits (130), Expect = 2e-06 Identities = 56/232 (24%), Positives = 98/232 (42%), Gaps = 22/232 (9%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRG------------QTALMQACQYGHWEVVQT 684 LH A + + L+ SG ++N G QT L A +G E VQ Sbjct: 729 LHRAVDENNESTACFLIRSGCDVNSPRQPGTNGEGEEEARDGQTPLHLAASWGLEETVQC 788 Query: 685 LMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSI----------PNFLNQT 834 L+ F AN++ D G T +H A + H+ ++L+++ P+I F Sbjct: 789 LLEFGANVNAQD-AEGRTPVHVAISNQHSVIIQLLISH--PNIELSVRDRQGLTPFACAM 845 Query: 835 KHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTI 1014 +++++ + G + V+ K G LH+A N +E V L+ + A+V+ + Sbjct: 846 TYKNNKAAEAILKRESGAAEQVDNK---GRNFLHVAVQNSDIESVLFLISVQANVNS-RV 901 Query: 1015 EDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 +D + + TPLH A G+ + + L+ GA + T L +A Sbjct: 902 QDASKL-------TPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLA 946 Score = 46.2 bits (108), Expect = 6e-04 Identities = 69/248 (27%), Positives = 102/248 (41%), Gaps = 16/248 (6%) Frame = +1 Query: 562 GHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH-RTDYLNGGT 738 G H I + LL SG IN GQT L A Q + L+ A+I+ RT +G T Sbjct: 600 GMHTIAAQLLGSGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQ--DGET 657 Query: 739 AIHFAALHG-----HARCLR---LVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 A+ A H A C R + + D + P +L + E+++ Sbjct: 658 ALQLAIKHQLPLVVDAICTRGADMSVPDEKGNPPLWLALASNL--EDIASTLVRHGCDAT 715 Query: 895 MVNWKADGGL-TPLHMAALNGHVECVQLLLDLGASVSEVTIE--DGTTIDLLGSGSTPLH 1065 G L T LH A + L+ G V+ +G + G TPLH Sbjct: 716 CWGPGPSGCLQTLLHRAVDENNESTACFLIRSGCDVNSPRQPGTNGEGEEEARDGQTPLH 775 Query: 1066 YAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQI----R 1233 AA G Q L+ GAN+ A++A G TP+ VA S + I ++L + P ++ R Sbjct: 776 LAASWGLEETVQCLLEFGANVNAQDAEGRTPVHVAISNQHSVIIQLLISHPNIELSVRDR 835 Query: 1234 TLPSPYLC 1257 +P+ C Sbjct: 836 QGLTPFAC 843 Score = 46.2 bits (108), Expect = 6e-04 Identities = 50/235 (21%), Positives = 80/235 (34%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A ++ D++ L+ + + +PLH A G IV LL +G ++N Sbjct: 878 AVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTK 937 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 QTAL A Q + L+ + D NG A+H A +HG +R +L + Sbjct: 938 HRQTALHLAAQQDLPTICSVLLENGVDFAAVDE-NGNNALHLAVMHGRLNNIRALLTECT 996 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 F + G +PLH+ G + Sbjct: 997 VDAEAFNLR-----------------------------GQSPLHILGQYGKENAAAIFDL 1027 Query: 985 LGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 + E ++ G+T L A GNA C+ ++ G L N G Sbjct: 1028 FLECMPEYPLDKPD-----AEGNTVLLLAYMKGNANLCRAIVRSGVRLGVNNNQG 1077 Score = 42.0 bits (97), Expect = 0.010 Identities = 59/264 (22%), Positives = 98/264 (37%), Gaps = 38/264 (14%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN-- 705 N L AA G+ L SG N RN G+T L AC++G + L+ AN Sbjct: 459 NCLLQRAAGAGNEAAALFLATSGAHANHRNKWGETPLHTACRHGLANLTAELLQQGANPN 518 Query: 706 ----------------IHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTK 837 + D + T +H A + H + ++L N L+ T Sbjct: 519 LQTEEALTLPKESPVLMSSADSIYLQTPLHMAIAYNHPDVVSVILEQKA----NALHATN 574 Query: 838 H-RSSEEVSDADFDDDGLVKMVNWKA-------------------DGGLTPLHMAALNGH 957 + + + S D D ++ + W G T LHMA Sbjct: 575 NLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQTLLHMAIQRQD 634 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 + LL+ A ++ T + T + L PL +A+C RGA+++ Sbjct: 635 SKSALFLLEHQADINVRTQDGETALQLAIKHQLPLVV-----DAIC-----TRGADMSVP 684 Query: 1138 NASGSTPLMVAHSWHRNSIEEILS 1209 + G+ PL +A + +++E+I S Sbjct: 685 DEKGNPPLWLALA---SNLEDIAS 705
>Q5UQZ7:YR901_MIMIV Putative ankyrin repeat protein R901 - Mimivirus| Length = 361 Score = 58.2 bits (139), Expect = 1e-07 Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 13/217 (5%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 +N + +A+ GH E+V L+ G I+ + A+ A Q GH EVV+ L+ NANI Sbjct: 139 KNYAIIWASRNGHIEVVEYLVSQGANISAED---NLAIRWASQNGHLEVVKYLVSLNANI 195 Query: 709 HR-TDYLNGGTAIHFAALHGHARCLRLVLA---------DYV---PSIPNFLNQTKHRSS 849 DY A+ +A+ +GH ++ ++ DY SI L K+ S Sbjct: 196 RADNDY-----AVRWASQNGHLEIVKYLVGQGANIRANDDYAVRWASINGHLEVVKYLVS 250 Query: 850 EEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTT 1029 ++ +D D+ VK A+ NGH++ V+ L+ GA ++T+E+ Sbjct: 251 QD-ADIRALDNSAVK--------------CASRNGHLKVVEYLVSSGA---DITVENNCA 292 Query: 1030 IDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKN 1140 I L A+ G+ + L+A+G ++ A+N Sbjct: 293 IGL----------ASRNGHLEVVKYLVAQGTDIRAEN 319
>P98150:NFKB2_CHICK Nuclear factor NF-kappa-B p100 subunit - Gallus gallus (Chicken)| Length = 906 Score = 58.2 bits (139), Expect = 1e-07 Identities = 73/254 (28%), Positives = 107/254 (42%), Gaps = 21/254 (8%) Frame = +1 Query: 469 EARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI------NLRNYRG 630 + R LL LA G ++PLH A ++ L+E V I N+ N Sbjct: 454 DPRMLLAVQRHLAASQDENG-DTPLHLAIIHEQTAVIKQLIEVVVSIPSQQIINITNNLQ 512 Query: 631 QTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLAD---- 798 QT L A +VVQ L+ +AN D G + +H A LR++LA Sbjct: 513 QTPLHLAVITKQPQVVQLLLEAHANPTLLDRY-GNSLLHLALQAADEEMLRMLLAHLASA 571 Query: 799 --YVPSIPNFLNQTK-HRSSEEVSDADFDDDGLVKMVNWKAD-------GGLTPLHMAAL 948 Y+ +PNF H + + S A D +V AD GG TPLH+A Sbjct: 572 TPYLLHLPNFQGLLPVHLAVKAKSPACLD-----LLVRKGADVNGVERQGGRTPLHLAVE 626 Query: 949 NGHVE-CVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGAN 1125 ++ L+ LGA+V+ T +G+TPLH AA G+ +LL+ GA+ Sbjct: 627 MENLNMATHLVKKLGANVNSRTF----------AGNTPLHLAAGLGSPTLTKLLLKAGAD 676 Query: 1126 LAAKNASGSTPLMV 1167 + +N +P V Sbjct: 677 VQRENDEPVSPSSV 690
>Q9QZH2:BARD1_RAT BRCA1-associated RING domain protein 1 - Rattus norvegicus (Rat)| Length = 768 Score = 58.2 bits (139), Expect = 1e-07 Identities = 29/85 (34%), Positives = 54/85 (63%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A+ +G V LL++G + N++++ G T L +AC +GH ++V+ L+ NA ++ T Sbjct: 422 LHIASIKGDISSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKIVELLLQHNALVNTTG 481 Query: 721 YLNGGTAIHFAALHGHARCLRLVLA 795 Y N + +H AA +GH ++++L+ Sbjct: 482 YHN-DSPLHDAAKNGHIDIVKVLLS 505 Score = 51.6 bits (122), Expect = 1e-05 Identities = 45/149 (30%), Positives = 62/149 (41%) Frame = +1 Query: 589 LESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGH 768 L SG+ RN+RG+T L A G V+ L L N N G T +H A HGH Sbjct: 405 LSSGIPARKRNHRGETLLHIASIKGDISSVEYL-LQNGNDPNVKDHAGWTPLHEACSHGH 463 Query: 769 ARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAAL 948 + + L+L + LV + D +PLH AA Sbjct: 464 LKIVELLL---------------------------QHNALVNTTGYHND---SPLHDAAK 493 Query: 949 NGHVECVQLLLDLGASVSEVTIEDGTTID 1035 NGH++ V++LL GAS + V I +D Sbjct: 494 NGHIDIVKVLLSHGASRNAVNIFGERPVD 522 Score = 44.7 bits (104), Expect = 0.002 Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 3/96 (3%) Frame = +1 Query: 427 GERLVSAAR-DGDLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLES 597 GE L+ A GD+ LL+ +P + ++ + +PLH A + GH +IV LLL+ Sbjct: 418 GETLLHIASIKGDISSVEYLLQNGNDPNVKDHAGW----TPLHEACSHGHLKIVELLLQH 473 Query: 598 GVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN 705 +N Y + L A + GH ++V+ L+ A+ Sbjct: 474 NALVNTTGYHNDSPLHDAAKNGHIDIVKVLLSHGAS 509 Score = 38.5 bits (88), Expect = 0.11 Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRN-SPLHYAAAQGHHEIVSLLLESGVEIN 612 L A G L+ LL++N A +T G N SPLH AA GH +IV +LL G N Sbjct: 455 LHEACSHGHLKIVELLLQHN---ALVNTTGYHNDSPLHDAAKNGHIDIVKVLLSHGASRN 511 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLML 693 N G+ + Y E +++L+L Sbjct: 512 AVNIFGE----RPVDYTDAENIRSLLL 534 Score = 35.4 bits (80), Expect = 0.97 Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 1/134 (0%) Frame = +1 Query: 814 PNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGA 993 P+ LN + HR G+ + G T LH+A++ G + V+ LL G Sbjct: 385 PSLLNNSTHRQMMSKPSTVKLSSGIP--ARKRNHRGETLLHIASIKGDISSVEYLLQNG- 441 Query: 994 SVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM-VA 1170 ++ ++D +G TPLH A G+ +LL+ A + +PL A Sbjct: 442 --NDPNVKDH-------AGWTPLHEACSHGHLKIVELLLQHNALVNTTGYHNDSPLHDAA 492 Query: 1171 HSWHRNSIEEILSN 1212 + H + ++ +LS+ Sbjct: 493 KNGHIDIVKVLLSH 506
>Q99728:BARD1_HUMAN BRCA1-associated RING domain protein 1 - Homo sapiens (Human)| Length = 777 Score = 58.2 bits (139), Expect = 1e-07 Identities = 30/85 (35%), Positives = 53/85 (62%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A+ +G V LL++G + N++++ G T L +AC +GH +VV+ L+ A ++ T Sbjct: 432 LHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTG 491 Query: 721 YLNGGTAIHFAALHGHARCLRLVLA 795 Y N + +H AA +GH ++L+L+ Sbjct: 492 YQN-DSPLHDAAKNGHVDIVKLLLS 515 Score = 49.3 bits (116), Expect = 6e-05 Identities = 42/133 (31%), Positives = 63/133 (47%) Frame = +1 Query: 616 RNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA 795 RN+RG+T L A G V+ L+ ++ + D+ G T +H A HGH + + L+L Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHA-GWTPLHEACNHGHLKVVELLL- 481 Query: 796 DYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQL 975 +H++ LV ++ D +PLH AA NGHV+ V+L Sbjct: 482 -------------QHKA-------------LVNTTGYQND---SPLHDAAKNGHVDIVKL 512 Query: 976 LLDLGASVSEVTI 1014 LL GAS + V I Sbjct: 513 LLSYGASRNAVNI 525 Score = 43.5 bits (101), Expect = 0.004 Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 3/96 (3%) Frame = +1 Query: 427 GERLVSAAR-DGDLQEARALLEY--NPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLES 597 GE L+ A GD+ LL+ +P + ++ + +PLH A GH ++V LLL+ Sbjct: 428 GETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGW----TPLHEACNHGHLKVVELLLQH 483 Query: 598 GVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN 705 +N Y+ + L A + GH ++V+ L+ + A+ Sbjct: 484 KALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGAS 519 Score = 37.4 bits (85), Expect = 0.26 Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Frame = +1 Query: 436 LVSAARDGDLQEARALLEYNPRLARYSTFGGRN-SPLHYAAAQGHHEIVSLLLESGVEIN 612 L A G L+ LL++ A +T G +N SPLH AA GH +IV LLL G N Sbjct: 465 LHEACNHGHLKVVELLLQHK---ALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRN 521 Query: 613 LRNYRGQTALMQACQYGHWEVVQTLML 693 N G ++ Y E +++L+L Sbjct: 522 AVNIFG----LRPVDYTDDESMKSLLL 544 Score = 33.5 bits (75), Expect = 3.7 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 1/98 (1%) Frame = +1 Query: 919 GLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 G T LH+A++ G + V+ LL G S+ ++D +G TPLH A G+ Sbjct: 428 GETLLHIASIKGDIPSVEYLLQNG---SDPNVKDH-------AGWTPLHEACNHGHLKVV 477 Query: 1099 QLLIARGANLAAKNASGSTPLM-VAHSWHRNSIEEILS 1209 +LL+ A + +PL A + H + ++ +LS Sbjct: 478 ELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLS 515
>Q1LZC5:ANR54_BOVIN Ankyrin repeat domain-containing protein 54 - Bos taurus (Bovine)| Length = 299 Score = 58.2 bits (139), Expect = 1e-07 Identities = 36/88 (40%), Positives = 48/88 (54%) Frame = +1 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAV 1092 D G T LH A+ NG+ + VQLLLD GA ++ G G+TPLH AAC +A Sbjct: 140 DKGRTALHFASCNGNDQIVQLLLDHGADPNQRD----------GLGNTPLHLAACTNHAP 189 Query: 1093 CCQLLIARGANLAAKNASGSTPLMVAHS 1176 L+ GA + A + +G TPL +A S Sbjct: 190 VITTLLRGGARVDALDRAGRTPLHLAKS 217 Score = 53.9 bits (128), Expect = 3e-06 Identities = 44/155 (28%), Positives = 70/155 (45%), Gaps = 10/155 (6%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 +RL +A D++ + LLE G + LH+A+ G+ +IV LLL+ G + Sbjct: 111 KRLRDSANANDVETVQQLLEEGTDPCAADDKG--RTALHFASCNGNDQIVQLLLDHGADP 168 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA------ALHGHA 771 N R+ G T L A H V+ TL+ A + D G T +H A GH+ Sbjct: 169 NQRDGLGNTPLHLAACTNHAPVITTLLRGGARVDALDRA-GRTPLHLAKSKLNILQEGHS 227 Query: 772 RCL---RLVLADYVPSIPNFLNQT-KHRSSEEVSD 864 +CL RL + + + +L + +H E + D Sbjct: 228 QCLEAVRLEVKQIIQMLREYLERLGRHEQRERLDD 262
>Q9J507:V228_FOWPV Putative ankyrin repeat protein FPV228 - Fowlpox virus (FPV)| Length = 525 Score = 57.8 bits (138), Expect = 2e-07 Identities = 46/217 (21%), Positives = 101/217 (46%), Gaps = 5/217 (2%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA + ++ +LL + ++N+ + G T L A + + E ++ L+ +N +++ Sbjct: 126 TPLHLAAESNNTTLLKILLYNNAKVNILDIYGNTCLHYAVRGRNIESIKLLLSYNVDVNI 185 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 ++ +A+H A G ++ R +++ + + N + + ++ + D + Sbjct: 186 RNFTYWYSALHEAVQIGDSKISRCIVSLLLCNKANVNTRCRLNTTPIFYAINCIDTLKLL 245 Query: 895 M-----VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTP 1059 + +N +D +H+A N + ++ LLD GA V+ + G TP Sbjct: 246 LENGADINATSDNDNAVIHLATENRRYDIIKTLLDYGADVNMIGYR----------GKTP 295 Query: 1060 LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 L+YA + +LL+ G+N + +TPL ++ Sbjct: 296 LYYATENYSYRNMKLLLDHGSNPNIADHIMNTPLFIS 332 Score = 50.1 bits (118), Expect = 4e-05 Identities = 51/211 (24%), Positives = 89/211 (42%), Gaps = 12/211 (5%) Frame = +1 Query: 544 HYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDY 723 H + +V++L + + I+ N+ L++A + + ++++TL+ + I+ D Sbjct: 12 HAVSINDRFSVVNILEKKNIPIDYINFHPDNPLLEAVKLTNTDMIKTLLDYGICINTRDI 71 Query: 724 LNGGTAIHFAAL----------HGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADF 873 L G TA+H A+ HGH DYV + +N Sbjct: 72 L-GNTALHLIAMDYYVPHNDIKHGHHN-------DYVFKMVPIINLF------------- 110 Query: 874 DDDGLVKMVNWKADGGL--TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS 1047 L K N A L TPLH+AA + + +++LL A V+ + I Sbjct: 111 ----LRKKANINACNNLNQTPLHLAAESNNTTLLKILLYNNAKVNILDI----------Y 156 Query: 1048 GSTPLHYAACGGNAVCCQLLIARGANLAAKN 1140 G+T LHYA G N +LL++ ++ +N Sbjct: 157 GNTCLHYAVRGRNIESIKLLLSYNVDVNIRN 187 Score = 41.2 bits (95), Expect = 0.018 Identities = 35/163 (21%), Positives = 70/163 (42%) Frame = +1 Query: 571 EIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHF 750 + + LLLE+G +IN + + A + +++++TL+ + A+++ Y G T +++ Sbjct: 240 DTLKLLLENGADINATSDNDNAVIHLATENRRYDIIKTLLDYGADVNMIGY-RGKTPLYY 298 Query: 751 AALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTP 930 A + R ++L+L H S+ ++D + TP Sbjct: 299 ATENYSYRNMKLLL--------------DHGSNPNIADHIMN----------------TP 328 Query: 931 LHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTP 1059 L ++ +E ++LLD GA ++ V T I L P Sbjct: 329 LFISIKCTCIENTKMLLDSGADINHVNDNGETPISYLAPNLIP 371 Score = 38.1 bits (87), Expect = 0.15 Identities = 18/71 (25%), Positives = 38/71 (53%) Frame = +1 Query: 514 STFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLML 693 +T N+ +H A ++I+ LL+ G ++N+ YRG+T L A + + ++ L+ Sbjct: 254 ATSDNDNAVIHLATENRRYDIIKTLLDYGADVNMIGYRGKTPLYYATENYSYRNMKLLLD 313 Query: 694 FNANIHRTDYL 726 +N + D++ Sbjct: 314 HGSNPNIADHI 324
>Q52T38:TIP1_ARATH Palmitoyltransferase TIP1 - Arabidopsis thaliana (Mouse-ear cress)| Length = 620 Score = 57.8 bits (138), Expect = 2e-07 Identities = 56/208 (26%), Positives = 88/208 (42%), Gaps = 1/208 (0%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWE-VVQTLMLFNANIHRT 717 LH++A +G ++ LLL+ G ++ + G A A QYG + + +NA+ Sbjct: 102 LHWSAVRGAIQVAELLLQEGARVDATDMYGYQATHVAAQYGQTAFLCHVVSKWNADPDVP 161 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM 897 D +G + +H+AA G A +RL+L FL+ + R +E Sbjct: 162 DN-DGRSPLHWAAYKGFADSIRLLL---------FLDAYRGRQDKE-------------- 197 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 G TPLH AA+ G++E +L+ G ++ I D T G TP AA Sbjct: 198 -------GCTPLHWAAIRGNLEACTVLVQAGKK-EDLMITDKT-------GLTPAQLAA- 241 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPL 1161 N + +L K GS+PL Sbjct: 242 EKNHRQVSFFLGNARSLLEKRCDGSSPL 269
>Q6S5H4:POT15_HUMAN Prostate, ovary, testis-expressed protein on chromosome 15 - Homo| sapiens (Human) Length = 581 Score = 57.8 bits (138), Expect = 2e-07 Identities = 60/239 (25%), Positives = 105/239 (43%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + + LH A+A G+ E+V LLL+ ++N+ + + +TAL++A Q E V L+ A+ Sbjct: 173 KRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADG 232 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + D G TA+H+ A++ + + L Y I + Sbjct: 233 NIQDEY-GNTALHY-AIYNEDKLMAKALLLYGADIES----------------------- 267 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 K GLTPL + + V+ L+ A+++ L G T L Sbjct: 268 ------KNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNA----------LDRYGRTALIL 311 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPS 1245 A C G+A LL+ + ++++++ SG T A S H + I E+LS+ Q+ + S Sbjct: 312 AVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISS 370 Score = 37.0 bits (84), Expect = 0.33 Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 1/111 (0%) Frame = +1 Query: 472 ARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQA 651 A+ALL Y + + G +PL + ++V L++ +N + G+TAL+ A Sbjct: 255 AKALLLYGADIESKNKCG--LTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILA 312 Query: 652 CQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA-ALHGHARCLRLVLADY 801 G +V L+ N ++ D L+G TA +A + H H C +L+DY Sbjct: 313 VCCGSASIVNLLLEQNVDVSSQD-LSGQTAREYAVSSHHHVIC--ELLSDY 360
>Q86YR6:ANR21_HUMAN Ankyrin repeat domain-containing protein 21 - Homo sapiens (Human)| Length = 584 Score = 57.8 bits (138), Expect = 2e-07 Identities = 60/239 (25%), Positives = 105/239 (43%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 + + LH A+A G+ E+V LLL+ ++N+ + + +TAL++A Q E V L+ A+ Sbjct: 173 KRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADR 232 Query: 709 HRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGL 888 + D G TA+H+ A++ + + L Y I + Sbjct: 233 NIPDEY-GNTALHY-AIYNEDKLMAKALLLYGADIES----------------------- 267 Query: 889 VKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHY 1068 K GLTPL + + V+ L+ A+++ L G T L Sbjct: 268 ------KNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNV----------LDRYGRTALIL 311 Query: 1069 AACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEILSNEPGGQIRTLPS 1245 A C G+A LL+ + ++++++ SG T A S H + I E+LS+ Q+ + S Sbjct: 312 AVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISS 370 Score = 37.7 bits (86), Expect = 0.20 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +1 Query: 472 ARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQA 651 A+ALL Y + + G +PL + ++V L++ +N+ + G+TAL+ A Sbjct: 255 AKALLLYGADIESKNKCG--LTPLLLGVHEQKQQVVKFLIKKKANLNVLDRYGRTALILA 312 Query: 652 CQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA-ALHGHARCLRLVLADY 801 G +V L+ N ++ D L+G TA +A + H H C +L+DY Sbjct: 313 VCCGSASIVNLLLEQNVDVSSQD-LSGQTAREYAVSSHHHVIC--ELLSDY 360
>Q6ZW76:ANKS3_HUMAN Ankyrin repeat and SAM domain-containing protein 3 - Homo sapiens| (Human) Length = 656 Score = 57.8 bits (138), Expect = 2e-07 Identities = 50/159 (31%), Positives = 65/159 (40%) Frame = +1 Query: 523 GGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNA 702 GG +PL YA+ GH IV LLLE+GV +N+ GQT LM A G+ + L+ A Sbjct: 67 GGGWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPEGQTPLMLASSCGNESIAYFLLQQGA 126 Query: 703 NIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 + D + G TA+ GH +R +L D Sbjct: 127 ELEMKD-IQGWTALFHCTSAGHQHMVRFLL----------------------------DS 157 Query: 883 GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASV 999 G V + G TPL AA GH VQ L+ G V Sbjct: 158 GANANVR-EPICGFTPLMEAAAAGHEIIVQYFLNHGVKV 195 Score = 53.1 bits (126), Expect = 5e-06 Identities = 37/115 (32%), Positives = 56/115 (48%), Gaps = 1/115 (0%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRN-YRGQTALMQACQYGHWEVVQTLMLFNANIHRT 717 L + + GH +V LL+SG N+R G T LM+A GH +VQ + + Sbjct: 139 LFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEAAAAGHEIIVQYFLNHGVKVDAR 198 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDD 882 D+ +G TA A +GH + + L + Y PS+P L +RS E+ D D+ Sbjct: 199 DH-SGATARMLAKQYGHMKIVAL-MDTYSPSLPKSL----YRSPEKYEDLSSSDE 247 Score = 51.6 bits (122), Expect = 1e-05 Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 1/147 (0%) Frame = +1 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 +N K GG TPL A+ GH V LLL+ G SV+ T E G TPL A+ Sbjct: 62 LNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPE----------GQTPLMLASS 111 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLM-VAHSWHRNSIEEILSNEPGGQIRTLPSPYL 1254 GN L+ +GA L K+ G T L + H++ + +L + +R + Sbjct: 112 CGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGF- 170 Query: 1255 CLPLMSIMSIARECGWRYLNKSPVCID 1335 PLM + E +Y V +D Sbjct: 171 -TPLMEAAAAGHEIIVQYFLNHGVKVD 196 Score = 49.3 bits (116), Expect = 6e-05 Identities = 24/63 (38%), Positives = 39/63 (61%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PL AAA GH IV L GV+++ R++ G TA M A QYGH ++V + ++ ++ + Sbjct: 171 TPLMEAAAAGHEIIVQYFLNHGVKVDARDHSGATARMLAKQYGHMKIVALMDTYSPSLPK 230 Query: 715 TDY 723 + Y Sbjct: 231 SLY 233 Score = 47.8 bits (112), Expect = 2e-04 Identities = 56/223 (25%), Positives = 89/223 (39%), Gaps = 1/223 (0%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESG-VEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT 717 LH AA+ G +E+V ++ +++N +N G T LM A GH +V L+ +++ Sbjct: 39 LHTAASIGQYEVVKECVQRRELDLNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVN-V 97 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM 897 G T + A+ G+ SI FL Q E+ D Sbjct: 98 PTPEGQTPLMLASSCGNE------------SIAYFLLQ----QGAELEMKDIQ------- 134 Query: 898 VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAAC 1077 G T L GH V+ LLD GA+ + + G TPL AA Sbjct: 135 -------GWTALFHCTSAGHQHMVRFLLDSGANAN---------VREPICGFTPLMEAAA 178 Query: 1078 GGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 G+ + Q + G + A++ SG+T M+A + I ++ Sbjct: 179 AGHEIIVQYFLNHGVKVDARDHSGATARMLAKQYGHMKIVALM 221
>Q9P2R3:ANFY1_HUMAN Ankyrin repeat and FYVE domain-containing protein 1 - Homo sapiens| (Human) Length = 1169 Score = 57.8 bits (138), Expect = 2e-07 Identities = 63/235 (26%), Positives = 104/235 (44%), Gaps = 10/235 (4%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH- 711 +PLH AA+ G E V LLE G +N ++ G+T + A H ++Q L++ + +IH Sbjct: 772 TPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQ-LLVSHPDIHL 830 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 G T A + + +L + N K R+ V+ + D + ++ Sbjct: 831 NVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDN--KGRNFLHVAVQNSDIESVL 888 Query: 892 KMVNWKAD--------GGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS 1047 +++ A+ LTPLH+A G V+ LL GA V+E+T Sbjct: 889 FLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELT----------KH 938 Query: 1048 GSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHR-NSIEEILS 1209 T LH AA C +L+ G + AA + +G+ L +A R N+I +L+ Sbjct: 939 RQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLT 993 Score = 53.9 bits (128), Expect = 3e-06 Identities = 68/249 (27%), Positives = 100/249 (40%), Gaps = 22/249 (8%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTD 720 LH A + + LLE +IN+R G+TAL A + VV + A++ D Sbjct: 626 LHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPD 685 Query: 721 YLNGGTAIHFAALHGHARCLRLVLADYV-------PSIPNFLNQTKHRSSEEVSD----- 864 G + AL + + L + P L HR+ +E ++ Sbjct: 686 --EKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACF 743 Query: 865 -----ADFDDD---GLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIED 1020 D + G +A G TPLH+AA G E VQ LL+ GA+V+ E Sbjct: 744 LIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAE- 802 Query: 1021 GTTIDLLGSGSTPLHYAACGGNAVCCQLLIAR-GANLAAKNASGSTPLMVAHSWHRN-SI 1194 G TP+H A + V QLL++ +L ++ G TP A ++ N S Sbjct: 803 ---------GRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSA 853 Query: 1195 EEILSNEPG 1221 E IL E G Sbjct: 854 EAILKRESG 862 Score = 52.0 bits (123), Expect = 1e-05 Identities = 59/233 (25%), Positives = 96/233 (41%), Gaps = 23/233 (9%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEINLRNYRG------------QTALMQACQYGHWEVVQT 684 LH A + + L+ SG ++N G QT L A +G E VQ Sbjct: 729 LHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQC 788 Query: 685 LMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLA---------DYVPSIPNFLNQT- 834 L+ F AN++ D G T IH A H ++L+++ D P T Sbjct: 789 LLEFGANVNAQD-AEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTF 847 Query: 835 -KHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVT 1011 ++S+E + + G + V+ K G LH+A N +E V L+ + A+V+ Sbjct: 848 KNNKSAEAILKR---ESGAAEQVDNK---GRNFLHVAVQNSDIESVLFLISVHANVNS-R 900 Query: 1012 IEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA 1170 ++D + + TPLH A G+ + + L+ GA + T L +A Sbjct: 901 VQDASKL-------TPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLA 946 Score = 50.8 bits (120), Expect = 2e-05 Identities = 55/238 (23%), Positives = 89/238 (37%), Gaps = 3/238 (1%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A ++ D++ L+ + + + +PLH A G IV LL +G ++N Sbjct: 878 AVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTK 937 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 QTAL A Q + L+ + D NG A+H A +HG +R++L + Sbjct: 938 HRQTALHLAAQQDLPTICSVLLENGVDFAAVDE-NGNNALHLAVMHGRLNNIRVLLTECT 996 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 F + G +PLH+ G + Sbjct: 997 VDAEAFNLR-----------------------------GQSPLHILGQYGK--------E 1019 Query: 985 LGASVSEVTIE--DGTTIDLL-GSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASG 1149 A++ ++ +E G +D GST L A GNA C+ ++ GA L N G Sbjct: 1020 NAAAIFDLFLECMPGYPLDKPDADGSTVLLLAYMKGNANLCRAIVRSGARLGVNNNQG 1077 Score = 45.1 bits (105), Expect = 0.001 Identities = 64/287 (22%), Positives = 106/287 (36%), Gaps = 51/287 (17%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNAN-- 705 N L AA G+ L +G +N RN G+T L AC++G + L+ AN Sbjct: 459 NCLLQRAAGAGNEAAALFLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPN 518 Query: 706 ----------------IHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTK 837 D ++ T +H A + H + ++L N L+ T Sbjct: 519 LQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKA----NALHATN 574 Query: 838 H-RSSEEVSDADFDDDGLVKMVNWKA-------------------DGGLTPLHMAALNGH 957 + + + S D D ++ + W G T LHMA Sbjct: 575 NLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQD 634 Query: 958 VECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAK 1137 + LL+ A ++ T + T + L PL +A+C RGA+++ Sbjct: 635 SKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVV-----DAIC-----TRGADMSVP 684 Query: 1138 NASGSTPLMVAHSWHRNSIEEILSN-------------EPGGQIRTL 1239 + G+ PL +A + N++E+I S PGG ++TL Sbjct: 685 DEKGNPPLWLALA---NNLEDIASTLVRHGCDATCWGPGPGGCLQTL 728 Score = 39.7 bits (91), Expect = 0.051 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 2/84 (2%) Frame = +1 Query: 925 TPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGS-GSTPLHYAACGGNA-VCC 1098 TPLH+ AL + ++ A ++E ++ G ++ S G TPLH + GN V Sbjct: 325 TPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFS 384 Query: 1099 QLLIARGANLAAKNASGSTPLMVA 1170 QLL + +L K+ GST L +A Sbjct: 385 QLLQCKQLDLELKDHEGSTALWLA 408
>Q9J5I7:V014_FOWPV Putative ankyrin repeat protein FPV014 - Fowlpox virus (FPV)| Length = 437 Score = 57.4 bits (137), Expect = 2e-07 Identities = 62/247 (25%), Positives = 101/247 (40%), Gaps = 23/247 (9%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 S LH A G+ EI +LL G +L TAL +A H+++V LM FN + Sbjct: 35 SLLHCAVENGNTEIARILLLEGANPDLYTESTPTALHRAVILRHYDIVNLLMEFNVDPDN 94 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVK 894 + T + +A + + +L DY AD +D + Sbjct: 95 YENHESRTPLEYAVKLNDVKMTKTLL-DY--------------------GADAED---IY 130 Query: 895 MVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTI-------------D 1035 N P++ AA NG++E +LL+D GA ++ ++ TI + Sbjct: 131 RFN-------CPINDAAANGNLEICKLLIDAGARINSRSMGSVYTIHHAIRSGNYELVVE 183 Query: 1036 LLGSGSTP----------LHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHR 1185 LL G+ P LH+A G+A L+ GA++ ++ G TPL +A + Sbjct: 184 LLSRGALPDVEDELSFSSLHHAVMEGSADMVLTLLEHGASVDVQDFCGRTPLFLAANASE 243 Query: 1186 NSIEEIL 1206 I ++L Sbjct: 244 LDIVKVL 250 Score = 50.4 bits (119), Expect = 3e-05 Identities = 49/186 (26%), Positives = 82/186 (44%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A + D++ + LL+Y F N P++ AAA G+ EI LL+++G IN R+ Sbjct: 107 AVKLNDVKMTKTLLDYGADAEDIYRF---NCPINDAAANGNLEICKLLIDAGARINSRSM 163 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYV 804 + A + G++E+V L+ A D L+ +++H A + G A + +L Sbjct: 164 GSVYTIHHAIRSGNYELVVELLSRGALPDVEDELS-FSSLHHAVMEGSADMVLTLL---- 218 Query: 805 PSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLD 984 +H +S +V D G TPL +AA ++ V++LLD Sbjct: 219 ----------EHGASVDVQDF----------------CGRTPLFLAANASELDIVKVLLD 252 Query: 985 LGASVS 1002 A S Sbjct: 253 FWADTS 258
>Q9Z2F6:BCL3_MOUSE B-cell lymphoma 3-encoded protein homolog - Mus musculus (Mouse)| Length = 440 Score = 57.4 bits (137), Expect = 2e-07 Identities = 64/220 (29%), Positives = 89/220 (40%), Gaps = 4/220 (1%) Frame = +1 Query: 529 RNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANI 708 R +PLH A ++V LL+ +G + GQTA+ AC++ +Q L L +A Sbjct: 159 RQTPLHLAVITTLPDMVRLLVTAGASPMALDRHGQTAIHLACEHRSPSCLQAL-LDSATS 217 Query: 709 HRTDY----LNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFD 876 D G TA+H A G + L+L E +D D Sbjct: 218 GSVDLEVRNYEGLTALHVAVNTGCQEAVLLLL-------------------ERGADIDAV 258 Query: 877 DDGLVKMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGST 1056 D G +PL A N + VQLLL GA+V+ + SGS+ Sbjct: 259 D----------IKSGRSPLIHAVENNSLNMVQLLLLHGANVNA----------QMYSGSS 298 Query: 1057 PLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHS 1176 LH A+ G + L+ GA+ KN TPLMVA S Sbjct: 299 ALHSASGRGLLPLVRTLVRSGADSGLKNCHNDTPLMVARS 338 Score = 34.3 bits (77), Expect = 2.2 Identities = 27/87 (31%), Positives = 38/87 (43%) Frame = +1 Query: 445 AARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNY 624 A G + LLE + GR SPL +A +V LLL G +N + Y Sbjct: 236 AVNTGCQEAVLLLLERGADIDAVDIKSGR-SPLIHAVENNSLNMVQLLLLHGANVNAQMY 294 Query: 625 RGQTALMQACQYGHWEVVQTLMLFNAN 705 G +AL A G +V+TL+ A+ Sbjct: 295 SGSSALHSASGRGLLPLVRTLVRSGAD 321
>Q566C8:ANR54_RAT Ankyrin repeat domain-containing protein 54 - Rattus norvegicus (Rat)| Length = 299 Score = 57.4 bits (137), Expect = 2e-07 Identities = 36/88 (40%), Positives = 49/88 (55%) Frame = +1 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAV 1092 D G T LH A+ NG+ + VQLLLD GA ++ +DG G+TPLH AAC + Sbjct: 140 DKGRTALHFASCNGNDQIVQLLLDHGADPNQ---QDGL-------GNTPLHLAACTNHVP 189 Query: 1093 CCQLLIARGANLAAKNASGSTPLMVAHS 1176 L+ GA + A + +G TPL +A S Sbjct: 190 VITTLLRGGARVDALDRAGRTPLHLAKS 217 Score = 52.0 bits (123), Expect = 1e-05 Identities = 43/155 (27%), Positives = 70/155 (45%), Gaps = 10/155 (6%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 +RL +A D++ + LLE G + LH+A+ G+ +IV LLL+ G + Sbjct: 111 KRLRDSANANDIETVQQLLEDGADPCAADDKG--RTALHFASCNGNDQIVQLLLDHGADP 168 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA------ALHGHA 771 N ++ G T L A H V+ TL+ A + D G T +H A GH+ Sbjct: 169 NQQDGLGNTPLHLAACTNHVPVITTLLRGGARVDALDRA-GRTPLHLAKSKLNILQEGHS 227 Query: 772 RCL---RLVLADYVPSIPNFLNQT-KHRSSEEVSD 864 +CL RL + + + +L + +H E + D Sbjct: 228 QCLEAVRLEVKQIIHMLREYLERLGRHEQRERLDD 262 Score = 40.8 bits (94), Expect = 0.023 Identities = 30/83 (36%), Positives = 41/83 (49%) Frame = +1 Query: 922 LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQ 1101 L L +A +E VQ LL+ GA D D G T LH+A+C GN Q Sbjct: 110 LKRLRDSANANDIETVQQLLEDGA--------DPCAAD--DKGRTALHFASCNGNDQIVQ 159 Query: 1102 LLIARGANLAAKNASGSTPLMVA 1170 LL+ GA+ ++ G+TPL +A Sbjct: 160 LLLDHGADPNQQDGLGNTPLHLA 182
>Q91WK7:ANR54_MOUSE Ankyrin repeat domain-containing protein 54 - Mus musculus (Mouse)| Length = 299 Score = 57.4 bits (137), Expect = 2e-07 Identities = 36/88 (40%), Positives = 49/88 (55%) Frame = +1 Query: 913 DGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAV 1092 D G T LH A+ NG+ + VQLLLD GA ++ +DG G+TPLH AAC + Sbjct: 140 DKGRTALHFASCNGNDQIVQLLLDHGADPNQ---QDGL-------GNTPLHLAACTNHVP 189 Query: 1093 CCQLLIARGANLAAKNASGSTPLMVAHS 1176 L+ GA + A + +G TPL +A S Sbjct: 190 VITTLLRGGARVDALDRAGRTPLHLAKS 217 Score = 51.6 bits (122), Expect = 1e-05 Identities = 43/155 (27%), Positives = 70/155 (45%), Gaps = 10/155 (6%) Frame = +1 Query: 430 ERLVSAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEI 609 +RL +A D++ + LLE G + LH+A+ G+ +IV LLL+ G + Sbjct: 111 KRLRDSANANDVETVQQLLEDGADPCAADDKG--RTALHFASCNGNDQIVQLLLDHGADP 168 Query: 610 NLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFA------ALHGHA 771 N ++ G T L A H V+ TL+ A + D G T +H A GH+ Sbjct: 169 NQQDGLGNTPLHLAACTNHVPVITTLLRGGARVDALDRA-GRTPLHLAKSKLNILQEGHS 227 Query: 772 RCL---RLVLADYVPSIPNFLNQT-KHRSSEEVSD 864 +CL RL + + + +L + +H E + D Sbjct: 228 QCLEAVRLEVKQIIHMLREYLERLGRHEQRERLDD 262 Score = 41.2 bits (95), Expect = 0.018 Identities = 31/83 (37%), Positives = 41/83 (49%) Frame = +1 Query: 922 LTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQ 1101 L L +A VE VQ LL+ GA D D G T LH+A+C GN Q Sbjct: 110 LKRLRDSANANDVETVQQLLEDGA--------DPCAAD--DKGRTALHFASCNGNDQIVQ 159 Query: 1102 LLIARGANLAAKNASGSTPLMVA 1170 LL+ GA+ ++ G+TPL +A Sbjct: 160 LLLDHGADPNQQDGLGNTPLHLA 182
>Q6UB98:ANR12_HUMAN Ankyrin repeat domain-containing protein 12 - Homo sapiens (Human)| Length = 2062 Score = 57.4 bits (137), Expect = 2e-07 Identities = 49/148 (33%), Positives = 75/148 (50%), Gaps = 2/148 (1%) Frame = +1 Query: 769 ARCLRLVLADYVP-SIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAA 945 A +++ D P S PN +QT + S + D VN + + G TPLHMAA Sbjct: 138 ALLMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKD----KVNKRNERGETPLHMAA 193 Query: 946 LNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGAN 1125 + G V+ V+ L+ LGA+V+ ++D +G TPLH A G ++LIA GA+ Sbjct: 194 IRGDVKQVKELISLGANVN---VKD-------FAGWTPLHEACNVGYYDVAKILIAAGAD 243 Query: 1126 LAAKNASGSTPLM-VAHSWHRNSIEEIL 1206 + + TPL A S HR+ ++ +L Sbjct: 244 VNTQGLDDDTPLHDSASSGHRDIVKLLL 271 Score = 55.5 bits (132), Expect = 9e-07 Identities = 28/86 (32%), Positives = 52/86 (60%) Frame = +1 Query: 535 SPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHR 714 +PLH AA +G + V L+ G +N++++ G T L +AC G+++V + L+ A+++ Sbjct: 187 TPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVN- 245 Query: 715 TDYLNGGTAIHFAALHGHARCLRLVL 792 T L+ T +H +A GH ++L+L Sbjct: 246 TQGLDDDTPLHDSASSGHRDIVKLLL 271 Score = 44.3 bits (103), Expect = 0.002 Identities = 37/145 (25%), Positives = 63/145 (43%) Frame = +1 Query: 604 EINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLR 783 ++N RN RG+T L A G + V+ L+ AN++ D+ G T +H A G+ + Sbjct: 177 KVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFA-GWTPLHEACNVGYYDVAK 235 Query: 784 LVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGGLTPLHMAALNGHVE 963 +++A + +V+ DDD TPLH +A +GH + Sbjct: 236 ILIA----------------AGADVNTQGLDDD--------------TPLHDSASSGHRD 265 Query: 964 CVQLLLDLGASVSEVTIEDGTTIDL 1038 V+LLL G + + +D+ Sbjct: 266 IVKLLLRHGGNAFQANKHGERPVDV 290
>Q8IUH5:ZDH17_HUMAN Palmitoyltransferase ZDHHC17 - Homo sapiens (Human)| Length = 632 Score = 57.0 bits (136), Expect = 3e-07 Identities = 62/229 (27%), Positives = 91/229 (39%), Gaps = 9/229 (3%) Frame = +1 Query: 541 LHYAAAQGHHEIVSLLLESGVEIN-LRNYRGQTALMQACQYGHWEVVQTLMLFNANIHRT 717 LH+AA ++V + G ++ L T L A + GH +V LM + A+ Sbjct: 94 LHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLI 153 Query: 718 DYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKM 897 D G + IH AA GH + ++A + D D D Sbjct: 154 DG-EGCSCIHLAAQFGHTSIVAYLIA-------------------KGQDVDMMDQN---- 189 Query: 898 VNWKADGGLTPLHMAALNGH-VECVQLLLDLGASVSEVTIEDGTTIDLLGSG---STPLH 1065 G+TPL AA H V+ +LLL SV+ LG +T LH Sbjct: 190 -------GMTPLMWAAYRTHSVDPTRLLLTFNVSVN------------LGDKYHKNTALH 230 Query: 1066 YAACGGNAVCCQLLIARGANLAAKNASGSTPLMVA----HSWHRNSIEE 1200 +A GN LL+ GAN+ A+N G + L +A + W N ++E Sbjct: 231 WAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQE 279 Score = 54.7 bits (130), Expect = 2e-06 Identities = 44/169 (26%), Positives = 75/169 (44%) Frame = +1 Query: 532 NSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQYGHWEVVQTLMLFNANIH 711 ++PLH+A QGH +V L++ G + +L + G + + A Q+GH +V L+ ++ Sbjct: 125 STPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVD 184 Query: 712 RTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLV 891 D NG T + +AA H+ +L + S+ L H++ Sbjct: 185 MMDQ-NGMTPLMWAAYRTHSVDPTRLLLTFNVSVN--LGDKYHKN--------------- 226 Query: 892 KMVNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL 1038 T LH A L G+ + LLL+ GA+V I+ + +DL Sbjct: 227 -----------TALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDL 264 Score = 41.2 bits (95), Expect = 0.018 Identities = 23/72 (31%), Positives = 41/72 (56%) Frame = +1 Query: 442 SAARDGDLQEARALLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRN 621 +A R + R LL +N + + +N+ LH+A G+ ++SLLLE+G ++ +N Sbjct: 197 AAYRTHSVDPTRLLLTFNVSVNLGDKYH-KNTALHWAVLAGNTTVISLLLEAGANVDAQN 255 Query: 622 YRGQTALMQACQ 657 +G++AL A Q Sbjct: 256 IKGESALDLAKQ 267
>Q5UPF8:YL088_MIMIV Putative ankyrin repeat protein L88 - Mimivirus| Length = 879 Score = 57.0 bits (136), Expect = 3e-07 Identities = 65/227 (28%), Positives = 100/227 (44%), Gaps = 6/227 (2%) Frame = +1 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGH----WEVVQTLMLFNANIHRTDYLNGGTA 741 +++LLL+ G +IN R+ G TALM A + + V+ L+ +ANI D NG T Sbjct: 120 VINLLLKYGADINARDNNGYTALMNASSNSNSSSTYTTVKLLLDNDANIDDKDK-NGLTC 178 Query: 742 IHFAALHGHARCLRLVLADYVPSIPNFLNQTKHRSSEEVSDADFDDDGLVKMVNWKADGG 921 + A C + L + +I L AD +N + G Sbjct: 179 LMHA-------CNNVTLKSSIGTIELLLYY----------GAD---------INAVDNNG 212 Query: 922 LTPL-HMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDLLGSGSTPLHYAACGGNAVCC 1098 T L H + ++E ++LLL+ GA + V + G T ++ S YA + Sbjct: 213 RTALMHACDNSNNIELIELLLNRGADIEAVDYK-GLTCLMIAS-----KYAGSINSVEVV 266 Query: 1099 QLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEI-LSNEPGGQIRT 1236 ++LI RGAN+ A+N TPLM A + N+ I L + G I T Sbjct: 267 EILINRGANIEARNEKLRTPLMYACKYSHNNTSVIKLLLDKGANIET 313 Score = 49.7 bits (117), Expect = 5e-05 Identities = 59/233 (25%), Positives = 99/233 (42%), Gaps = 20/233 (8%) Frame = +1 Query: 526 GRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQY----GHWEVVQTLML 693 GR + +H + E++ LLL G +I +Y+G T LM A +Y EVV+ L+ Sbjct: 212 GRTALMHACDNSNNIELIELLLNRGADIEAVDYKGLTCLMIASKYAGSINSVEVVEILIN 271 Query: 694 FNANIH-RTDYLNGGTAIHFAALHGHARCLRLVL--------ADYVPSIPNFLNQTKHRS 846 ANI R + L H + ++L+L D + L T + S Sbjct: 272 RGANIEARNEKLRTPLMYACKYSHNNTSVIKLLLDKGANIETTDLRNNTALILAST-YSS 330 Query: 847 SEEVSDADFDDDGLVKMVNWKADGGLTPLHMAAL----NGHVECVQLLLDLGASVSEVTI 1014 S E D + N D G L++A + N + E V+LL+D G++++ + Sbjct: 331 SVEPIKLLLDKGANINHTN---DEGCNALNLACINSSYNNNSEIVKLLIDRGSNINNMDS 387 Query: 1015 ED---GTTIDLLGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLM 1164 E +T + +G GS N ++L+ A+ N +G+T L+ Sbjct: 388 ERTILTSTCEFIGKGS----------NIDTVKILLDNNADPNIPNTNGNTTLL 430 Score = 42.7 bits (99), Expect = 0.006 Identities = 56/238 (23%), Positives = 103/238 (43%), Gaps = 26/238 (10%) Frame = +1 Query: 571 EIVSLLLESGVEINLRNYRGQTALMQACQYGHW----EVVQTLMLFNANIHRTDYLNG-- 732 E + LLL+ G IN N G AL AC + E+V+ L+ +NI+ D Sbjct: 333 EPIKLLLDKGANINHTNDEGCNALNLACINSSYNNNSEIVKLLIDRGSNINNMDSERTIL 392 Query: 733 GTAIHFAALHGHARCLRLVLADYV-PSIPNFLNQTK--HRSSEEVSDADFDDD---GLVK 894 + F + ++++L + P+IPN T + + + D D ++K Sbjct: 393 TSTCEFIGKGSNIDTVKILLDNNADPNIPNTNGNTTLLYMCKKYIKDGPKKRDLNFNVIK 452 Query: 895 M----------VNWKADGGLTPLHMAALNGHVECVQLLLDLGASVSEVTIEDGTTIDL-- 1038 + +N K + LT L + +E ++LLLD G ++ + + L Sbjct: 453 LLLDYKANPNFINKKNENSLTRLSKYSDKVDIEIIKLLLDYGVDINSTNNYCNSALLLFC 512 Query: 1039 --LGSGSTPLHYAACGGNAVCCQLLIARGANLAAKNASGSTPLMVAHSWHRNSIEEIL 1206 L + T + Y N V +LL+ +GA++ N++G+T L + N++ +I+ Sbjct: 513 MDLQNSCTKISYNC--KNIV--KLLLEKGADVNIINSNGNTALSIICESDDNNLSDII 566 Score = 39.7 bits (91), Expect = 0.051 Identities = 35/151 (23%), Positives = 70/151 (46%), Gaps = 7/151 (4%) Frame = +1 Query: 481 LLEYNPRLARYSTFGGRNSPLHYAAAQGHHEIVSLLLESGVEINLRNYRGQTALMQACQY 660 LL++ + G + LH + E + LLL++G + N+++ +G+TAL +A ++ Sbjct: 660 LLKHKTTKINFQNSSGITALLHECQVSDNIEPIKLLLDNGADPNIQDEKGETALHKAVRH 719 Query: 661 -GHWEVVQTLMLFNANIHRTDYLNGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQTK 837 +V++ LM ++AN + + N G + A +R ++V N +N Sbjct: 720 TNKIDVIKLLMDYHANPY--IFRNKGQDLLSYAFKKSSR------RNFVNIAKNLINNPC 771 Query: 838 HRSSEEVSDADFDDD------GLVKMVNWKA 912 H S+E F+ ++KM+ + A Sbjct: 772 HVLSDENRSQIFESKDKENIISIIKMLEYNA 802 Score = 38.9 bits (89), Expect = 0.088 Identities = 50/211 (23%), Positives = 87/211 (41%), Gaps = 38/211 (18%) Frame = +1 Query: 574 IVSLLLESGVEINLRNYRGQTALMQACQYGH---WEVVQTLMLFNAN------------- 705 IV LLLE G ++N+ N G TAL C+ ++++ L+ NAN Sbjct: 529 IVKLLLEKGADVNIINSNGNTALSIICESDDNNLSDIIELLLAHNANPNTINKEEYTPLM 588 Query: 706 --IHRTDYL---------------NGGTAIHFAALHGHARCLRLVLADYVPSIPNFLNQT 834 I R DY + + F + G ++ + V + I Sbjct: 589 HLIERFDYFLTNSKSIPQNIESDSDSDSMSGFESYRGFSQSSKSVNKYNLDKI------E 642 Query: 835 KHRSSEEVSDADFDDDGLVK----MVNWKADGGLTP-LHMAALNGHVECVQLLLDLGASV 999 K+++ E++ + + L+K +N++ G+T LH ++ ++E ++LLLD GA Sbjct: 643 KNKNEPEINYRQKNLEMLLKHKTTKINFQNSSGITALLHECQVSDNIEPIKLLLDNGA-- 700 Query: 1000 SEVTIEDGTTIDLLGSGSTPLHYAACGGNAV 1092 + I+D G T LH A N + Sbjct: 701 -DPNIQD-------EKGETALHKAVRHTNKI 723 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 394,354,416 Number of extensions: 9463187 Number of successful extensions: 38108 Number of sequences better than 10.0: 801 Number of HSP's gapped: 34594 Number of HSP's successfully gapped: 2466 Length of query: 718 Length of database: 100,686,439 Length adjustment: 121 Effective length of query: 597 Effective length of database: 67,496,744 Effective search space: 40295556168 Effective search space used: 40295556168 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
