Clone Information

BLAST Search Result

Clone Name	FLbaf39n07
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	Q9SZ30:HIS5_ARATH Imidazole glycerol phosphate synthase hisHF, c...	848	0.0
2	O94303:HIS5_SCHPO Imidazole glycerol phosphate synthase hisHF - ...	544	e-154
3	Q9P4P9:HIS5_EMENI Imidazole glycerol phosphate synthase hisHF - ...	527	e-149
4	P33734:HIS5_YEAST Imidazole glycerol phosphate synthase hisHF - ...	520	e-147
5	Q8TYW8:HIS6_METKA Imidazole glycerol phosphate synthase subunit ...	192	6e-48
6	O29439:HIS6_ARCFU Imidazole glycerol phosphate synthase subunit ...	189	4e-47
7	O27398:HIS6_METTH Imidazole glycerol phosphate synthase subunit ...	186	2e-46
8	Q5V2C9:HIS6_HALMA Imidazole glycerol phosphate synthase subunit ...	186	4e-46
9	P60666:HIS6_MYCPA Imidazole glycerol phosphate synthase subunit ...	185	7e-46
10	Q57854:HIS6_METJA Imidazole glycerol phosphate synthase subunit ...	184	9e-46
11	Q3INY2:HIS6_NATPD Imidazole glycerol phosphate synthase subunit ...	183	2e-45
12	Q4JW52:HIS6_CORJK Imidazole glycerol phosphate synthase subunit ...	183	3e-45
13	Q3A135:HIS5_PELCD Imidazole glycerol phosphate synthase subunit ...	181	8e-45
14	Q9HR52:HIS6_HALSA Imidazole glycerol phosphate synthase subunit ...	180	2e-44
15	Q8R885:HIS6_THETN Imidazole glycerol phosphate synthase subunit ...	179	3e-44
16	O31139:HIS6_CORGL Imidazole glycerol phosphate synthase subunit ...	179	5e-44
17	O66567:HIS6_AQUAE Imidazole glycerol phosphate synthase subunit ...	177	2e-43
18	O27568:HIS5_METTH Imidazole glycerol phosphate synthase subunit ...	176	2e-43
19	Q8TT96:HIS6_METAC Imidazole glycerol phosphate synthase subunit ...	176	3e-43
20	Q97KH8:HIS6_CLOAB Imidazole glycerol phosphate synthase subunit ...	176	4e-43
21	Q8FNZ9:HIS6_COREF Imidazole glycerol phosphate synthase subunit ...	175	5e-43
22	Q8PW92:HIS6_METMA Imidazole glycerol phosphate synthase subunit ...	174	1e-42
23	Q46CC5:HIS6_METBF Imidazole glycerol phosphate synthase subunit ...	174	1e-42
24	Q30PY0:HIS5_THIDN Imidazole glycerol phosphate synthase subunit ...	172	4e-42
25	Q8ZY16:HIS6_PYRAE Imidazole glycerol phosphate synthase subunit ...	172	5e-42
26	O53908:HIS6_MYCTU Imidazole glycerol phosphate synthase subunit ...	172	6e-42
27	Q7VEW8:HIS6_MYCBO Imidazole glycerol phosphate synthase subunit ...	172	6e-42
28	Q9RPQ4:HIS6_THEET Imidazole glycerol phosphate synthase subunit ...	171	1e-41
29	Q8GDQ6:HIS6_HELMO Imidazole glycerol phosphate synthase subunit ...	171	1e-41
30	Q7NNK4:HIS5_GLOVI Imidazole glycerol phosphate synthase subunit ...	171	1e-41
31	Q7UKJ9:HIS6_RHOBA Imidazole glycerol phosphate synthase subunit ...	171	1e-41
32	Q465U3:HIS5_METBF Imidazole glycerol phosphate synthase subunit ...	171	1e-41
33	P60714:HIS6_CORDI Imidazole glycerol phosphate synthase subunit ...	169	3e-41
34	P60599:HIS5_GEOSL Imidazole glycerol phosphate synthase subunit ...	169	3e-41
35	Q7ULP3:HIS5_RHOBA Imidazole glycerol phosphate synthase subunit ...	169	5e-41
36	Q47QS3:HIS6_THEFY Imidazole glycerol phosphate synthase subunit ...	168	7e-41
37	Q5KVC8:HIS5_GEOKA Imidazole glycerol phosphate synthase subunit ...	168	7e-41
38	O66943:HIS5_AQUAE Imidazole glycerol phosphate synthase subunit ...	168	7e-41
39	Q81G02:HIS6_BACCR Imidazole glycerol phosphate synthase subunit ...	167	1e-40
40	Q2RGW0:HIS5_MOOTA Imidazole glycerol phosphate synthase subunit ...	167	1e-40
41	Q8TS91:HIS5_METAC Imidazole glycerol phosphate synthase subunit ...	167	2e-40
42	P61782:HIS51_METMP Imidazole glycerol phosphate synthase subunit...	167	2e-40
43	Q9X7C2:HIS6_MYCLE Imidazole glycerol phosphate synthase subunit ...	166	4e-40
44	P62454:HIS6_METMP Imidazole glycerol phosphate synthase subunit ...	166	4e-40
45	Q5YYP3:HIS6_NOCFA Imidazole glycerol phosphate synthase subunit ...	165	6e-40
46	Q92E88:HIS6_LISIN Imidazole glycerol phosphate synthase subunit ...	165	6e-40
47	Q8R883:HIS5_THETN Imidazole glycerol phosphate synthase subunit ...	165	6e-40
48	Q63DW8:HIS6_BACCZ Imidazole glycerol phosphate synthase subunit ...	165	7e-40
49	Q3ZY50:HIS5_DEHSC Imidazole glycerol phosphate synthase subunit ...	165	7e-40
50	P60715:HIS6_GEOSL Imidazole glycerol phosphate synthase subunit ...	164	1e-39
51	Q92E86:HIS5_LISIN Imidazole glycerol phosphate synthase subunit ...	164	1e-39
52	Q39YP2:HIS6_GEOMG Imidazole glycerol phosphate synthase subunit ...	164	1e-39
53	Q39YP4:HIS5_GEOMG Imidazole glycerol phosphate synthase subunit ...	164	2e-39
54	Q970Z0:HIS6_SULTO Imidazole glycerol phosphate synthase subunit ...	163	3e-39
55	O33774:HIS6_SULSO Imidazole glycerol phosphate synthase subunit ...	163	3e-39
56	Q8KF56:HIS5_CHLTE Imidazole glycerol phosphate synthase subunit ...	163	3e-39
57	P58800:HIS6_PYRFU Imidazole glycerol phosphate synthase subunit ...	162	6e-39
58	Q3A137:HIS6_PELCD Imidazole glycerol phosphate synthase subunit ...	162	6e-39
59	P62453:HIS6_THET2 Imidazole glycerol phosphate synthase subunit ...	161	8e-39
60	Q6HLE3:HIS6_BACHK Imidazole glycerol phosphate synthase subunit ...	161	8e-39
61	Q81T58:HIS6_BACAN Imidazole glycerol phosphate synthase subunit ...	161	8e-39
62	Q3B286:HIS5_PELLD Imidazole glycerol phosphate synthase subunit ...	161	8e-39
63	Q8PVD5:HIS5_METMA Imidazole glycerol phosphate synthase subunit ...	161	8e-39
64	Q8Y9G5:HIS6_LISMO Imidazole glycerol phosphate synthase subunit ...	161	1e-38
65	Q722Y7:HIS6_LISMF Imidazole glycerol phosphate synthase subunit ...	160	1e-38
66	P62449:HIS6_BACC1 Imidazole glycerol phosphate synthase subunit ...	160	1e-38
67	Q4KJS4:HIS6_PSEF5 Imidazole glycerol phosphate synthase subunit ...	160	2e-38
68	Q57929:HIS5_METJA Imidazole glycerol phosphate synthase subunit ...	160	2e-38
69	Q9K6Z4:HIS5_BACHD Imidazole glycerol phosphate synthase subunit ...	160	2e-38
70	Q8Y9G3:HIS5_LISMO Imidazole glycerol phosphate synthase subunit ...	160	2e-38
71	Q3Z7F2:HIS5_DEHE1 Imidazole glycerol phosphate synthase subunit ...	160	2e-38
72	Q7P0F1:HIS5_CHRVO Imidazole glycerol phosphate synthase subunit ...	160	2e-38
73	Q81G04:HIS5_BACCR Imidazole glycerol phosphate synthase subunit ...	160	2e-38
74	Q7SIB9:HIS6_THET8 Imidazole glycerol phosphate synthase subunit ...	159	3e-38
75	Q87UG4:HIS6_PSESM Imidazole glycerol phosphate synthase subunit ...	159	3e-38
76	Q3IUP8:HIS5_NATPD Imidazole glycerol phosphate synthase subunit ...	159	3e-38
77	Q9X0C6:HIS6_THEMA Imidazole glycerol phosphate synthase subunit ...	159	4e-38
78	Q88R41:HIS6_PSEPK Imidazole glycerol phosphate synthase subunit ...	159	4e-38
79	Q39K85:HIS6_BURS3 Imidazole glycerol phosphate synthase subunit ...	159	4e-38
80	Q63Q92:HIS6_BURPS Imidazole glycerol phosphate synthase subunit ...	159	4e-38
81	Q3JN02:HIS6_BURP1 Imidazole glycerol phosphate synthase subunit ...	159	4e-38
82	Q722Y5:HIS5_LISMF Imidazole glycerol phosphate synthase subunit ...	159	4e-38
83	Q5JFU8:HIS6_PYRKO Imidazole glycerol phosphate synthase subunit ...	159	5e-38
84	Q9HNI6:HIS5_HALSA Imidazole glycerol phosphate synthase subunit ...	159	5e-38
85	Q31E64:HIS6_THICR Imidazole glycerol phosphate synthase subunit ...	158	7e-38
86	Q4ZLQ2:HIS6_PSEU2 Imidazole glycerol phosphate synthase subunit ...	158	7e-38
87	Q3KJI5:HIS6_PSEPF Imidazole glycerol phosphate synthase subunit ...	158	7e-38
88	Q48C81:HIS6_PSE14 Imidazole glycerol phosphate synthase subunit ...	158	7e-38
89	Q5HT90:HIS51_CAMJR Imidazole glycerol phosphate synthase subunit...	158	7e-38
90	Q5HKP2:HIS6_STAEQ Imidazole glycerol phosphate synthase subunit ...	157	1e-37
91	Q62GE5:HIS6_BURMA Imidazole glycerol phosphate synthase subunit ...	157	1e-37
92	Q97KI0:HIS5_CLOAB Imidazole glycerol phosphate synthase subunit ...	157	1e-37
93	Q7V6M5:HIS52_PROMM Imidazole glycerol phosphate synthase subunit...	157	1e-37
94	Q0P8U2:HIS51_CAMJE Imidazole glycerol phosphate synthase subunit...	157	1e-37
95	Q603K3:HIS6_METCA Imidazole glycerol phosphate synthase subunit ...	157	2e-37
96	Q9RX89:HIS5_DEIRA Imidazole glycerol phosphate synthase subunit ...	157	2e-37
97	Q47AM3:HIS6_DECAR Imidazole glycerol phosphate synthase subunit ...	157	2e-37
98	Q3SWF1:HIS6_NITWN Imidazole glycerol phosphate synthase subunit ...	156	3e-37
99	Q5KVD0:HIS6_GEOKA Imidazole glycerol phosphate synthase subunit ...	156	3e-37
100	Q7P0E9:HIS6_CHRVO Imidazole glycerol phosphate synthase subunit ...	156	3e-37
101	Q7MAS1:HIS6_WOLSU Imidazole glycerol phosphate synthase subunit ...	155	4e-37
102	Q30NR6:HIS6_THIDN Imidazole glycerol phosphate synthase subunit ...	155	4e-37
103	Q820Q0:HIS6_NITEU Imidazole glycerol phosphate synthase subunit ...	155	4e-37
104	Q3J6Q3:HIS5_NITOC Imidazole glycerol phosphate synthase subunit ...	155	4e-37
105	Q63DX0:HIS5_BACCZ Imidazole glycerol phosphate synthase subunit ...	155	4e-37
106	Q7VBF5:HIS5_PROMA Imidazole glycerol phosphate synthase subunit ...	155	6e-37
107	Q5UYV3:HIS5_HALMA Imidazole glycerol phosphate synthase subunit ...	155	6e-37
108	Q7VSY8:HIS5_BORPE Imidazole glycerol phosphate synthase subunit ...	155	6e-37
109	Q2YAU8:HIS5_NITMU Imidazole glycerol phosphate synthase subunit ...	155	8e-37
110	Q7W2Y1:HIS5_BORPA Imidazole glycerol phosphate synthase subunit ...	155	8e-37
111	Q7WDY1:HIS5_BORBR Imidazole glycerol phosphate synthase subunit ...	155	8e-37
112	Q6F7A7:HIS5_ACIAD Imidazole glycerol phosphate synthase subunit ...	155	8e-37
113	A1W0U9:HIS51_CAMJJ Imidazole glycerol phosphate synthase subunit...	155	8e-37
114	Q82A99:HIS6_STRAW Imidazole glycerol phosphate synthase subunit ...	154	1e-36
115	Q8CQ92:HIS6_STAES Imidazole glycerol phosphate synthase subunit ...	154	1e-36
116	Q81T60:HIS5_BACAN Imidazole glycerol phosphate synthase subunit ...	154	1e-36
117	Q8DTR3:HIS6_STRMU Imidazole glycerol phosphate synthase subunit ...	154	1e-36
118	Q3MEF5:HIS6_ANAVT Imidazole glycerol phosphate synthase subunit ...	154	1e-36
119	P61778:HIS5_BACC1 Imidazole glycerol phosphate synthase subunit ...	154	1e-36
120	O28019:HIS5_ARCFU Imidazole glycerol phosphate synthase subunit ...	154	1e-36
121	P72138:HIS52_PSEAE Imidazole glycerol phosphate synthase subunit...	154	1e-36
122	Q9S2T7:HIS6_STRCO Imidazole glycerol phosphate synthase subunit ...	154	2e-36
123	Q8NUI3:HIS6_STAAW Imidazole glycerol phosphate synthase subunit ...	154	2e-36
124	Q6G602:HIS6_STAAS Imidazole glycerol phosphate synthase subunit ...	154	2e-36
125	Q5HCM4:HIS6_STAAC Imidazole glycerol phosphate synthase subunit ...	154	2e-36
126	Q6GDD1:HIS6_STAAR Imidazole glycerol phosphate synthase subunit ...	153	2e-36
127	Q2YZ71:HIS6_STAAB Imidazole glycerol phosphate synthase subunit ...	153	2e-36
128	Q2RGW2:HIS6_MOOTA Imidazole glycerol phosphate synthase subunit ...	153	2e-36
129	O34727:HIS6_BACSU Imidazole glycerol phosphate synthase subunit ...	153	2e-36
130	Q65EG3:HIS6_BACLD Imidazole glycerol phosphate synthase subunit ...	153	2e-36
131	Q8YT31:HIS6_ANASP Imidazole glycerol phosphate synthase subunit ...	153	2e-36
132	Q5MZ63:HIS5_SYNP6 Imidazole glycerol phosphate synthase subunit ...	153	2e-36
133	Q8DTR1:HIS5_STRMU Imidazole glycerol phosphate synthase subunit ...	153	2e-36
134	P61779:HIS5_DESVH Imidazole glycerol phosphate synthase subunit ...	153	2e-36
135	Q3SEU8:HIS6_THIDA Imidazole glycerol phosphate synthase subunit ...	153	3e-36
136	Q4J8I9:HIS6_SULAC Imidazole glycerol phosphate synthase subunit ...	153	3e-36
137	Q89WM4:HIS6_BRAJA Imidazole glycerol phosphate synthase subunit ...	153	3e-36
138	Q9HU44:HIS61_PSEAE Imidazole glycerol phosphate synthase subunit...	153	3e-36
139	Q7M9X0:HIS5_WOLSU Imidazole glycerol phosphate synthase subunit ...	153	3e-36
140	Q7VIW9:HIS5_HELHP Imidazole glycerol phosphate synthase subunit ...	153	3e-36
141	P60667:HIS6_RHOPA Imidazole glycerol phosphate synthase subunit ...	152	4e-36
142	Q8G6F7:HIS6_BIFLO Imidazole glycerol phosphate synthase subunit ...	152	4e-36
143	Q5P795:HIS6_AZOSE Imidazole glycerol phosphate synthase subunit ...	152	4e-36
144	P64362:HIS6_STAAN Imidazole glycerol phosphate synthase subunit ...	152	5e-36
145	P64361:HIS6_STAAM Imidazole glycerol phosphate synthase subunit ...	152	5e-36
146	Q46WL8:HIS6_RALEJ Imidazole glycerol phosphate synthase subunit ...	152	5e-36
147	Q845U7:HIS6_BURCE Imidazole glycerol phosphate synthase subunit ...	152	5e-36
148	Q8DIP5:HIS5_SYNEL Imidazole glycerol phosphate synthase subunit ...	151	8e-36
149	Q7MPK8:HIS53_VIBVY Imidazole glycerol phosphate synthase subunit...	151	8e-36
150	Q7VDF1:HIS6_PROMA Imidazole glycerol phosphate synthase subunit ...	150	1e-35
151	Q8XV85:HIS6_RALSO Imidazole glycerol phosphate synthase subunit ...	150	2e-35
152	Q3B2Q6:HIS6_PELLD Imidazole glycerol phosphate synthase subunit ...	150	2e-35
153	Q3Z7F5:HIS6_DEHE1 Imidazole glycerol phosphate synthase subunit ...	150	2e-35
154	Q67KH8:HIS5_SYMTH Imidazole glycerol phosphate synthase subunit ...	150	2e-35
155	Q5P793:HIS5_AZOSE Imidazole glycerol phosphate synthase subunit ...	150	2e-35
156	Q4FPZ3:HIS6_PSYAR Imidazole glycerol phosphate synthase subunit ...	150	2e-35
157	Q3ZY29:HIS6_DEHSC Imidazole glycerol phosphate synthase subunit ...	150	2e-35
158	Q7W2X9:HIS6_BORPA Imidazole glycerol phosphate synthase subunit ...	149	3e-35
159	Q4A049:HIS6_STAS1 Imidazole glycerol phosphate synthase subunit ...	149	4e-35
160	Q3AD48:HIS6_CARHZ Imidazole glycerol phosphate synthase subunit ...	149	4e-35
161	Q7VSY6:HIS6_BORPE Imidazole glycerol phosphate synthase subunit ...	149	4e-35
162	Q7WDX9:HIS6_BORBR Imidazole glycerol phosphate synthase subunit ...	149	4e-35
163	Q5WDI0:HIS5_BACSK Imidazole glycerol phosphate synthase subunit ...	149	4e-35
164	Q6HLE5:HIS5_BACHK Imidazole glycerol phosphate synthase subunit ...	149	4e-35
165	Q46GY9:HIS6_PROMT Imidazole glycerol phosphate synthase subunit ...	149	5e-35
166	Q2YAV0:HIS6_NITMU Imidazole glycerol phosphate synthase subunit ...	149	5e-35
167	P58789:HIS5_PYRFU Imidazole glycerol phosphate synthase subunit ...	149	5e-35
168	Q4FNT5:HIS5_PELUB Imidazole glycerol phosphate synthase subunit ...	149	5e-35
169	Q3ATG0:HIS6_CHLCH Imidazole glycerol phosphate synthase subunit ...	148	7e-35
170	Q55805:HIS5_SYNY3 Imidazole glycerol phosphate synthase subunit ...	148	7e-35
171	Q6A7Y8:HIS6_PROAC Imidazole glycerol phosphate synthase subunit ...	148	9e-35
172	Q3AT63:HIS5_CHLCH Imidazole glycerol phosphate synthase subunit ...	148	9e-35
173	Q7V2P2:HIS6_PROMP Imidazole glycerol phosphate synthase subunit ...	147	1e-34
174	Q4ZLP9:HIS5_PSEU2 Imidazole glycerol phosphate synthase subunit ...	147	1e-34
175	Q31AG5:HIS5_PROM9 Imidazole glycerol phosphate synthase subunit ...	147	1e-34
176	P62450:HIS6_DESVH Imidazole glycerol phosphate synthase subunit ...	147	2e-34
177	Q9K6Z6:HIS6_BACHD Imidazole glycerol phosphate synthase subunit ...	147	2e-34
178	Q7V127:HIS5_PROMP Imidazole glycerol phosphate synthase subunit ...	147	2e-34
179	Q31CA5:HIS6_PROM9 Imidazole glycerol phosphate synthase subunit ...	147	2e-34
180	Q8ESS2:HIS6_OCEIH Imidazole glycerol phosphate synthase subunit ...	147	2e-34
181	Q9JVH5:HIS6_NEIMA Imidazole glycerol phosphate synthase subunit ...	147	2e-34
182	Q5FA23:HIS6_NEIG1 Imidazole glycerol phosphate synthase subunit ...	147	2e-34
183	Q8KCB0:HIS6_CHLTE Imidazole glycerol phosphate synthase subunit ...	147	2e-34
184	Q6F799:HIS6_ACIAD Imidazole glycerol phosphate synthase subunit ...	147	2e-34
185	Q31E66:HIS5_THICR Imidazole glycerol phosphate synthase subunit ...	147	2e-34
186	Q7U899:HIS52_SYNPX Imidazole glycerol phosphate synthase subunit...	147	2e-34
187	Q5WYE9:HIS51_LEGPL Imidazole glycerol phosphate synthase subunit...	147	2e-34
188	Q3J6Q1:HIS6_NITOC Imidazole glycerol phosphate synthase subunit ...	146	3e-34
189	Q3KJI8:HIS5_PSEPF Imidazole glycerol phosphate synthase subunit ...	146	3e-34
190	Q603K1:HIS5_METCA Imidazole glycerol phosphate synthase subunit ...	146	3e-34
191	Q47AM1:HIS5_DECAR Imidazole glycerol phosphate synthase subunit ...	146	3e-34
192	P61783:HIS52_METMP Imidazole glycerol phosphate synthase subunit...	146	3e-34
193	Q9K0H4:HIS6_NEIMB Imidazole glycerol phosphate synthase subunit ...	146	4e-34
194	Q4KJS7:HIS5_PSEF5 Imidazole glycerol phosphate synthase subunit ...	146	4e-34
195	Q5N0H4:HIS6_SYNP6 Imidazole glycerol phosphate synthase subunit ...	145	5e-34
196	Q4FPU1:HIS5_PSYAR Imidazole glycerol phosphate synthase subunit ...	145	5e-34
197	Q65EG1:HIS5_BACLD Imidazole glycerol phosphate synthase subunit ...	145	5e-34
198	Q5NMD4:HIS5_ZYMMO Imidazole glycerol phosphate synthase subunit ...	145	6e-34
199	Q316L3:HIS5_DESDG Imidazole glycerol phosphate synthase subunit ...	145	6e-34
200	P48262:HIS5_CYAPA Imidazole glycerol phosphate synthase subunit ...	145	6e-34
201	Q7MPP4:HIS52_VIBVY Imidazole glycerol phosphate synthase subunit...	145	6e-34
202	Q3Z0G2:HIS5_SHISS Imidazole glycerol phosphate synthase subunit ...	145	8e-34
203	Q83KJ5:HIS5_SHIFL Imidazole glycerol phosphate synthase subunit ...	145	8e-34
204	Q32EF2:HIS5_SHIDS Imidazole glycerol phosphate synthase subunit ...	145	8e-34
205	Q323I9:HIS5_SHIBS Imidazole glycerol phosphate synthase subunit ...	145	8e-34
206	P60595:HIS5_ECOLI Imidazole glycerol phosphate synthase subunit ...	145	8e-34
207	P60596:HIS5_ECOL6 Imidazole glycerol phosphate synthase subunit ...	145	8e-34
208	Q3M5W4:HIS5_ANAVT Imidazole glycerol phosphate synthase subunit ...	145	8e-34
209	Q88R44:HIS5_PSEPK Imidazole glycerol phosphate synthase subunit ...	144	1e-33
210	Q3AD50:HIS5_CARHZ Imidazole glycerol phosphate synthase subunit ...	144	1e-33
211	Q8DJN7:HIS6_SYNEL Imidazole glycerol phosphate synthase subunit ...	144	2e-33
212	Q316L4:HIS6_DESDG Imidazole glycerol phosphate synthase subunit ...	144	2e-33
213	Q5WDI2:HIS6_BACSK Imidazole glycerol phosphate synthase subunit ...	144	2e-33
214	Q8G4S6:HIS5_BIFLO Imidazole glycerol phosphate synthase subunit ...	144	2e-33
215	O34565:HIS5_BACSU Imidazole glycerol phosphate synthase subunit ...	143	2e-33
216	Q2RNA5:HIS5_RHORT Imidazole glycerol phosphate synthase subunit ...	143	3e-33
217	Q67KI0:HIS6_SYMTH Imidazole glycerol phosphate synthase subunit ...	142	4e-33
218	Q3SEU6:HIS5_THIDA Imidazole glycerol phosphate synthase subunit ...	142	4e-33
219	Q87UG1:HIS5_PSESM Imidazole glycerol phosphate synthase subunit ...	142	4e-33
220	Q48C78:HIS5_PSE14 Imidazole glycerol phosphate synthase subunit ...	142	4e-33
221	Q9RDX3:HIS5_LEGPN Imidazole glycerol phosphate synthase subunit ...	142	4e-33
222	Q5ZXI1:HIS51_LEGPH Imidazole glycerol phosphate synthase subunit...	142	4e-33
223	Q5X6Z7:HIS51_LEGPA Imidazole glycerol phosphate synthase subunit...	142	4e-33
224	Q7V8Q8:HIS61_PROMM Imidazole glycerol phosphate synthase subunit...	142	5e-33
225	Q8PLG8:HIS5_XANAC Imidazole glycerol phosphate synthase subunit ...	142	5e-33
226	P58237:HIS5_ECO57 Imidazole glycerol phosphate synthase subunit ...	142	5e-33
227	Q9ZGM1:HIS5_LEPBO Imidazole glycerol phosphate synthase subunit ...	142	7e-33
228	Q9HU42:HIS51_PSEAE Imidazole glycerol phosphate synthase subunit...	142	7e-33
229	Q98CT1:HIS6_RHILO Imidazole glycerol phosphate synthase subunit ...	141	9e-33
230	Q7VGZ1:HIS6_HELHP Imidazole glycerol phosphate synthase subunit ...	141	9e-33
231	Q9TLQ8:HIS5_CYACA Imidazole glycerol phosphate synthase subunit ...	141	9e-33
232	Q92TB3:HIS6_RHIME Imidazole glycerol phosphate synthase subunit ...	141	1e-32
233	P26721:HIS6_AZOBR Imidazole glycerol phosphate synthase subunit ...	141	1e-32
234	Q4FNT7:HIS6_PELUB Imidazole glycerol phosphate synthase subunit ...	140	2e-32
235	Q9KSX0:HIS5_VIBCH Imidazole glycerol phosphate synthase subunit ...	140	2e-32
236	Q5X5X2:HIS52_LEGPA Imidazole glycerol phosphate synthase subunit...	140	2e-32
237	Q5JFV0:HIS5_PYRKO Imidazole glycerol phosphate synthase subunit ...	140	3e-32
238	Q9A231:HIS5_CAUCR Imidazole glycerol phosphate synthase subunit ...	140	3e-32
239	Q8YX49:HIS5_ANASP Imidazole glycerol phosphate synthase subunit ...	140	3e-32
240	Q66C52:HIS5_YERPS Imidazole glycerol phosphate synthase subunit ...	139	3e-32
241	Q8ZFX8:HIS5_YERPE Imidazole glycerol phosphate synthase subunit ...	139	3e-32
242	Q8P9P1:HIS5_XANCP Imidazole glycerol phosphate synthase subunit ...	139	3e-32
243	Q4UU43:HIS5_XANC8 Imidazole glycerol phosphate synthase subunit ...	139	3e-32
244	Q63Q90:HIS5_BURPS Imidazole glycerol phosphate synthase subunit ...	139	3e-32
245	Q3JN00:HIS5_BURP1 Imidazole glycerol phosphate synthase subunit ...	139	3e-32
246	Q62GE3:HIS5_BURMA Imidazole glycerol phosphate synthase subunit ...	139	3e-32
247	Q9S4H8:HIS52_LEPIN Imidazole glycerol phosphate synthase subunit...	139	3e-32
248	Q8FY07:HIS6_BRUSU Imidazole glycerol phosphate synthase subunit ...	139	4e-32
249	Q57AH3:HIS6_BRUAB Imidazole glycerol phosphate synthase subunit ...	139	4e-32
250	Q2YQY8:HIS6_BRUA2 Imidazole glycerol phosphate synthase subunit ...	139	4e-32
251	Q8YE37:HIS6_BRUME Imidazole glycerol phosphate synthase subunit ...	139	6e-32
252	Q8ESS0:HIS5_OCEIH Imidazole glycerol phosphate synthase subunit ...	139	6e-32
253	Q5WX94:HIS52_LEGPL Imidazole glycerol phosphate synthase subunit...	139	6e-32
254	Q5FTN3:HIS6_GLUOX Imidazole glycerol phosphate synthase subunit ...	138	7e-32
255	Q7NDC1:HIS6_GLOVI Imidazole glycerol phosphate synthase subunit ...	138	7e-32
256	Q3BUF4:HIS5_XANC5 Imidazole glycerol phosphate synthase subunit ...	138	7e-32
257	Q5ZW90:HIS52_LEGPH Imidazole glycerol phosphate synthase subunit...	138	7e-32
258	Q02133:HIS6_LACLA Imidazole glycerol phosphate synthase subunit ...	138	1e-31
259	P60598:HIS5_CORDI Imidazole glycerol phosphate synthase subunit ...	138	1e-31
260	Q845U9:HIS5_BURCE Imidazole glycerol phosphate synthase subunit ...	138	1e-31
261	Q5H0K8:HIS5_XANOR Imidazole glycerol phosphate synthase subunit ...	137	1e-31
262	Q2P3K0:HIS5_XANOM Imidazole glycerol phosphate synthase subunit ...	137	1e-31
263	P0A1R4:HIS5_SALTY Imidazole glycerol phosphate synthase subunit ...	137	1e-31
264	P0A1R5:HIS5_SALTI Imidazole glycerol phosphate synthase subunit ...	137	1e-31
265	Q5PDP6:HIS5_SALPA Imidazole glycerol phosphate synthase subunit ...	137	1e-31
266	Q57MS0:HIS5_SALCH Imidazole glycerol phosphate synthase subunit ...	137	1e-31
267	Q820D2:HIS5_NITEU Imidazole glycerol phosphate synthase subunit ...	137	1e-31
268	P60597:HIS5_BDEBA Imidazole glycerol phosphate synthase subunit ...	137	1e-31
269	Q5LU99:HIS6_SILPO Imidazole glycerol phosphate synthase subunit ...	137	2e-31
270	Q7U5M8:HIS61_SYNPX Imidazole glycerol phosphate synthase subunit...	137	2e-31
271	Q46JZ5:HIS5_PROMT Imidazole glycerol phosphate synthase subunit ...	137	2e-31
272	Q9A229:HIS6_CAUCR Imidazole glycerol phosphate synthase subunit ...	137	2e-31
273	Q5NMD6:HIS6_ZYMMO Imidazole glycerol phosphate synthase subunit ...	136	3e-31
274	Q6AF73:HIS6_LEIXX Imidazole glycerol phosphate synthase subunit ...	136	3e-31
275	Q5QWQ7:HIS5_IDILO Imidazole glycerol phosphate synthase subunit ...	136	3e-31
276	P74106:HIS6_SYNY3 Imidazole glycerol phosphate synthase subunit ...	136	4e-31
277	Q2RNA7:HIS6_RHORT Imidazole glycerol phosphate synthase subunit ...	136	4e-31
278	Q9RWD7:HIS6_DEIRA Imidazole glycerol phosphate synthase subunit ...	136	4e-31
279	Q47XB3:HIS6_COLP3 Imidazole glycerol phosphate synthase subunit ...	135	5e-31
280	Q8D8Q3:HIS5_VIBVU Imidazole glycerol phosphate synthase subunit ...	135	5e-31
281	Q6A8L2:HIS5_PROAC Imidazole glycerol phosphate synthase subunit ...	135	5e-31
282	Q7MLS3:HIS51_VIBVY Imidazole glycerol phosphate synthase subunit...	135	5e-31
283	Q5E635:HIS5_VIBF1 Imidazole glycerol phosphate synthase subunit ...	135	8e-31
284	Q8EFB4:HIS5_SHEON Imidazole glycerol phosphate synthase subunit ...	135	8e-31
285	Q8TV83:HIS5_METKA Imidazole glycerol phosphate synthase subunit ...	135	8e-31
286	Q87C32:HIS5_XYLFT Imidazole glycerol phosphate synthase subunit ...	134	1e-30
287	P61780:HIS5_LEPIC Imidazole glycerol phosphate synthase subunit ...	134	1e-30
288	Q39K87:HIS5_BURS3 Imidazole glycerol phosphate synthase subunit ...	134	1e-30
289	P59118:HIS51_LEPIN Imidazole glycerol phosphate synthase subunit...	134	1e-30
290	Q7SIC0:HIS5_THET8 Imidazole glycerol phosphate synthase subunit ...	134	1e-30
291	P61781:HIS5_THET2 Imidazole glycerol phosphate synthase subunit ...	134	1e-30
292	Q88UE1:HIS5_LACPL Imidazole glycerol phosphate synthase subunit ...	134	1e-30
293	Q64RT2:HIS6_BACFR Imidazole glycerol phosphate synthase subunit ...	134	2e-30
294	Q5YYP7:HIS5_NOCFA Imidazole glycerol phosphate synthase subunit ...	134	2e-30
295	Q8CTV0:HIS5_STAES Imidazole glycerol phosphate synthase subunit ...	133	2e-30
296	Q5HKP0:HIS5_STAEQ Imidazole glycerol phosphate synthase subunit ...	133	2e-30
297	Q9JVH3:HIS5_NEIMA Imidazole glycerol phosphate synthase subunit ...	133	2e-30
298	P60600:HIS5_MYCPA Imidazole glycerol phosphate synthase subunit ...	133	2e-30
299	P59957:HIS5_MYCBO Imidazole glycerol phosphate synthase subunit ...	133	2e-30
300	P58788:HIS5_AGRT5 Imidazole glycerol phosphate synthase subunit ...	133	2e-30
301	Q46WL6:HIS5_RALEJ Imidazole glycerol phosphate synthase subunit ...	132	4e-30
302	Q7MLS1:HIS61_VIBVY Imidazole glycerol phosphate synthase subunit...	132	5e-30
303	Q8D8Q5:HIS6_VIBVU Imidazole glycerol phosphate synthase subunit ...	132	7e-30
304	Q87QK6:HIS6_VIBPA Imidazole glycerol phosphate synthase subunit ...	132	7e-30
305	Q87QK8:HIS5_VIBPA Imidazole glycerol phosphate synthase subunit ...	132	7e-30
306	Q9PBC8:HIS5_XYLFA Imidazole glycerol phosphate synthase subunit ...	131	9e-30
307	O06589:HIS5_MYCTU Imidazole glycerol phosphate synthase subunit ...	131	9e-30
308	Q3SWE9:HIS51_NITWN Imidazole glycerol phosphate synthase subunit...	131	9e-30
309	Q8A7Z6:HIS6_BACTN Imidazole glycerol phosphate synthase subunit ...	131	1e-29
310	Q4J8I5:HIS5_SULAC Imidazole glycerol phosphate synthase subunit ...	131	1e-29
311	P50937:HIS6_RHOS4 Imidazole glycerol phosphate synthase subunit ...	130	2e-29
312	Q5LBD7:HIS6_BACFN Imidazole glycerol phosphate synthase subunit ...	130	2e-29
313	P62448:HIS5_PHOPR Imidazole glycerol phosphate synthase subunit ...	130	2e-29
314	Q5FA21:HIS5_NEIG1 Imidazole glycerol phosphate synthase subunit ...	130	2e-29
315	O30724:HIS6_RHOCA Imidazole glycerol phosphate synthase subunit ...	130	3e-29
316	P62451:HIS6_LEPIC Imidazole glycerol phosphate synthase subunit ...	129	3e-29
317	P59119:HIS61_LEPIN Imidazole glycerol phosphate synthase subunit...	129	3e-29
318	Q7U924:HIS51_SYNPX Imidazole glycerol phosphate synthase subunit...	129	3e-29
319	Q6AE14:HIS5_LEIXX Imidazole glycerol phosphate synthase subunit ...	129	6e-29
320	Q6D408:HIS5_ERWCT Imidazole glycerol phosphate synthase subunit ...	128	8e-29
321	O69043:HIS5_CORGL Imidazole glycerol phosphate synthase subunit ...	128	8e-29
322	Q8P9N9:HIS6_XANCP Imidazole glycerol phosphate synthase subunit ...	128	1e-28
323	Q4UU45:HIS6_XANC8 Imidazole glycerol phosphate synthase subunit ...	128	1e-28
324	Q970Y7:HIS5_SULTO Imidazole glycerol phosphate synthase subunit ...	128	1e-28
325	P16249:HIS5_STRCO Imidazole glycerol phosphate synthase subunit ...	128	1e-28
326	Q8XV83:HIS5_RALSO Imidazole glycerol phosphate synthase subunit ...	128	1e-28
327	Q9X7C0:HIS5_MYCLE Imidazole glycerol phosphate synthase subunit ...	128	1e-28
328	Q89WM6:HIS5_BRAJA Imidazole glycerol phosphate synthase subunit ...	128	1e-28
329	Q65RC1:HIS6_MANSM Imidazole glycerol phosphate synthase subunit ...	127	1e-28
330	Q88UE3:HIS6_LACPL Imidazole glycerol phosphate synthase subunit ...	127	1e-28
331	P58799:HIS6_AGRT5 Imidazole glycerol phosphate synthase subunit ...	127	1e-28
332	Q9K0H2:HIS5_NEIMB Imidazole glycerol phosphate synthase subunit ...	127	1e-28
333	P44340:HIS5_HAEIN Imidazole glycerol phosphate synthase subunit ...	127	1e-28
334	Q4QN71:HIS5_HAEI8 Imidazole glycerol phosphate synthase subunit ...	127	1e-28
335	Q02132:HIS5_LACLA Imidazole glycerol phosphate synthase subunit ...	127	2e-28
336	P64365:HIS5_STAAW Imidazole glycerol phosphate synthase subunit ...	127	2e-28
337	Q6G600:HIS5_STAAS Imidazole glycerol phosphate synthase subunit ...	127	2e-28
338	P64364:HIS5_STAAN Imidazole glycerol phosphate synthase subunit ...	127	2e-28
339	P64363:HIS5_STAAM Imidazole glycerol phosphate synthase subunit ...	127	2e-28
340	Q5HCM2:HIS5_STAAC Imidazole glycerol phosphate synthase subunit ...	127	2e-28
341	Q7N6I5:HIS6_PHOLL Imidazole glycerol phosphate synthase subunit ...	126	3e-28
342	Q6GDC9:HIS5_STAAR Imidazole glycerol phosphate synthase subunit ...	126	4e-28
343	Q2YZ69:HIS5_STAAB Imidazole glycerol phosphate synthase subunit ...	126	4e-28
344	Q7N6I3:HIS5_PHOLL Imidazole glycerol phosphate synthase subunit ...	125	5e-28
345	Q6D406:HIS6_ERWCT Imidazole glycerol phosphate synthase subunit ...	125	6e-28
346	Q3SPZ6:HIS52_NITWN Imidazole glycerol phosphate synthase subunit...	125	6e-28
347	Q9KSW8:HIS6_VIBCH Imidazole glycerol phosphate synthase subunit ...	125	8e-28
348	Q8CX42:HIS6_SHEON Imidazole glycerol phosphate synthase subunit ...	125	8e-28
349	P57206:HIS6_BUCAI Imidazole glycerol phosphate synthase subunit ...	125	8e-28
350	Q47QS5:HIS5_THEFY Imidazole glycerol phosphate synthase subunit ...	125	8e-28
351	Q98CT5:HIS5_RHILO Imidazole glycerol phosphate synthase subunit ...	125	8e-28
352	Q5FTN5:HIS5_GLUOX Imidazole glycerol phosphate synthase subunit ...	125	8e-28
353	Q7V959:HIS51_PROMM Imidazole glycerol phosphate synthase subunit...	125	8e-28
354	Q5H0K6:HIS6_XANOR Imidazole glycerol phosphate synthase subunit ...	124	1e-27
355	Q2P3J8:HIS6_XANOM Imidazole glycerol phosphate synthase subunit ...	124	1e-27
356	Q5E633:HIS6_VIBF1 Imidazole glycerol phosphate synthase subunit ...	124	1e-27
357	Q3BUF2:HIS6_XANC5 Imidazole glycerol phosphate synthase subunit ...	124	1e-27
358	Q8PLG6:HIS6_XANAC Imidazole glycerol phosphate synthase subunit ...	123	2e-27
359	Q494D6:HIS6_BLOPB Imidazole glycerol phosphate synthase subunit ...	123	2e-27
360	O33777:HIS5_SULSO Imidazole glycerol phosphate synthase subunit ...	123	2e-27
361	O33565:HIS5_RHOS4 Imidazole glycerol phosphate synthase subunit ...	123	2e-27
362	P60601:HIS5_RHOPA Imidazole glycerol phosphate synthase subunit ...	123	2e-27
363	Q8FY09:HIS5_BRUSU Imidazole glycerol phosphate synthase subunit ...	123	2e-27
364	Q57AH5:HIS5_BRUAB Imidazole glycerol phosphate synthase subunit ...	123	2e-27
365	Q2YQZ0:HIS5_BRUA2 Imidazole glycerol phosphate synthase subunit ...	123	2e-27
366	P57204:HIS5_BUCAI Imidazole glycerol phosphate synthase subunit ...	123	3e-27
367	Q4JW55:HIS5_CORJK Imidazole glycerol phosphate synthase subunit ...	122	4e-27
368	Q8YE35:HIS5_BRUME Imidazole glycerol phosphate synthase subunit ...	122	4e-27
369	Q7VQW5:HIS6_BLOFL Imidazole glycerol phosphate synthase subunit ...	122	5e-27
370	P62452:HIS6_PHOPR Imidazole glycerol phosphate synthase subunit ...	122	7e-27
371	Q8FNZ6:HIS5_COREF Imidazole glycerol phosphate synthase subunit ...	122	7e-27
372	Q3Z0G0:HIS6_SHISS Imidazole glycerol phosphate synthase subunit ...	121	9e-27
373	Q3ICD4:HIS6_PSEHT Imidazole glycerol phosphate synthase subunit ...	121	9e-27
374	Q82AA2:HIS5_STRAW Imidazole glycerol phosphate synthase subunit ...	121	9e-27
375	Q5LU93:HIS5_SILPO Imidazole glycerol phosphate synthase subunit ...	121	9e-27
376	Q6KZD3:HIS5_PICTO Imidazole glycerol phosphate synthase subunit ...	121	9e-27
377	Q5LBD5:HIS5_BACFN Imidazole glycerol phosphate synthase subunit ...	121	9e-27
378	Q32EF4:HIS6_SHIDS Imidazole glycerol phosphate synthase subunit ...	121	1e-26
379	Q64RT0:HIS5_BACFR Imidazole glycerol phosphate synthase subunit ...	121	1e-26
380	P60664:HIS6_ECOLI Imidazole glycerol phosphate synthase subunit ...	120	2e-26
381	P60665:HIS6_ECO57 Imidazole glycerol phosphate synthase subunit ...	120	2e-26
382	Q4A047:HIS5_STAS1 Imidazole glycerol phosphate synthase subunit ...	120	2e-26
383	Q8A7Z4:HIS5_BACTN Imidazole glycerol phosphate synthase subunit ...	120	2e-26
384	Q83R03:HIS6_SHIFL Imidazole glycerol phosphate synthase subunit ...	120	2e-26
385	Q323I7:HIS6_SHIBS Imidazole glycerol phosphate synthase subunit ...	120	2e-26
386	P59521:HIS6_BUCBP Imidazole glycerol phosphate synthase subunit ...	120	2e-26
387	Q92TB1:HIS5_RHIME Imidazole glycerol phosphate synthase subunit ...	120	2e-26
388	P0A1R2:HIS6_SALTY Imidazole glycerol phosphate synthase subunit ...	120	3e-26
389	P0A1R3:HIS6_SALTI Imidazole glycerol phosphate synthase subunit ...	120	3e-26
390	Q5PDN6:HIS6_SALPA Imidazole glycerol phosphate synthase subunit ...	120	3e-26
391	Q57MR8:HIS6_SALCH Imidazole glycerol phosphate synthase subunit ...	119	4e-26
392	P44436:HIS6_HAEIN Imidazole glycerol phosphate synthase subunit ...	119	4e-26
393	Q4QN69:HIS6_HAEI8 Imidazole glycerol phosphate synthase subunit ...	119	4e-26
394	Q8FG48:HIS6_ECOL6 Imidazole glycerol phosphate synthase subunit ...	119	4e-26
395	Q5HSI8:HIS6_CAMJR Imidazole glycerol phosphate synthase subunit ...	118	8e-26
396	Q9PM72:HIS61_CAMJE Imidazole glycerol phosphate synthase subunit...	118	8e-26
397	P59501:HIS5_BUCBP Imidazole glycerol phosphate synthase subunit ...	118	8e-26
398	Q87C34:HIS6_XYLFT Imidazole glycerol phosphate synthase subunit ...	118	1e-25
399	Q66C54:HIS6_YERPS Imidazole glycerol phosphate synthase subunit ...	117	1e-25
400	Q9ZHE1:HIS6_BUCAP Imidazole glycerol phosphate synthase subunit ...	117	2e-25
401	Q9CLM0:HIS6_PASMU Imidazole glycerol phosphate synthase subunit ...	117	2e-25
402	Q8ZFY0:HIS6_YERPE Imidazole glycerol phosphate synthase subunit ...	116	3e-25
403	Q9PBD0:HIS6_XYLFA Imidazole glycerol phosphate synthase subunit ...	116	3e-25
404	P45603:HIS6_KLEOX Imidazole glycerol phosphate synthase subunit ...	116	3e-25
405	Q65RB8:HIS5_MANSM Imidazole glycerol phosphate synthase subunit ...	115	5e-25
406	P57921:HIS5_PASMU Imidazole glycerol phosphate synthase subunit ...	115	7e-25
407	Q8ZY40:HIS5_PYRAE Imidazole glycerol phosphate synthase subunit ...	115	9e-25
408	Q9ZHE3:HIS5_BUCAP Imidazole glycerol phosphate synthase subunit ...	115	9e-25
409	Q5QWQ5:HIS6_IDILO Imidazole glycerol phosphate synthase subunit ...	114	1e-24
410	Q5HSJ1:HIS52_CAMJR Imidazole glycerol phosphate synthase subunit...	114	2e-24
411	Q9PM75:HIS52_CAMJE Imidazole glycerol phosphate synthase subunit...	114	2e-24
412	Q492K0:HIS5_BLOPB Imidazole glycerol phosphate synthase subunit ...	113	3e-24
413	Q7VQW7:HIS5_BLOFL Imidazole glycerol phosphate synthase subunit ...	113	3e-24
414	Q85FY4:HIS5_CYAME Imidazole glycerol phosphate synthase subunit ...	112	4e-24
415	Q9RDX2:HIS6_LEGPN Imidazole glycerol phosphate synthase subunit ...	112	7e-24
416	Q47XB5:HIS5_COLP3 Imidazole glycerol phosphate synthase subunit ...	111	1e-23
417	Q9X0C8:HIS5_THEMA Imidazole glycerol phosphate synthase subunit ...	110	2e-23
418	P18785:HIS5_AZOBR Imidazole glycerol phosphate synthase subunit ...	107	2e-22
419	Q7V958:HIS62_PROMM Putative imidazole glycerol phosphate synthas...	100	2e-20
420	Q7MPP3:HIS62_VIBVY Putative imidazole glycerol phosphate synthas...	98	1e-19
421	Q84I55:HIS5_BUCMH Imidazole glycerol phosphate synthase subunit ...	94	2e-18
422	P72139:HIS62_PSEAE Putative imidazole glycerol phosphate synthas...	94	2e-18
423	Q84I54:HIS5_BUCSC Imidazole glycerol phosphate synthase subunit ...	92	6e-18
424	Q84I56:HIS5_BUCDN Imidazole glycerol phosphate synthase subunit ...	92	1e-17
425	A1W0U8:HIS62_CAMJJ Putative imidazole glycerol phosphate synthas...	82	6e-15
426	Q0P8U3:HIS62_CAMJE Putative imidazole glycerol phosphate synthas...	82	1e-14
427	Q9ZGM0:HIS6_LEPBO Putative imidazole glycerol phosphate synthase...	80	2e-14
428	Q7MPK7:HIS63_VIBVY Putative imidazole glycerol phosphate synthas...	80	2e-14
429	Q9S4H7:HIS62_LEPIN Putative imidazole glycerol phosphate synthas...	78	1e-13
430	Q7U923:HIS62_SYNPX Putative imidazole glycerol phosphate synthas...	72	7e-12
431	Q46CW8:HIS4_METBF 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	71	1e-11
432	O26931:HIS4_METTH 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	68	2e-10
433	Q2NHB3:HIS4_METST 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	65	1e-09
434	Q0W0J3:HIS4_UNCMA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	64	2e-09
435	Q8TU55:HIS4_METAC 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	63	4e-09
436	P62357:HIS4_METMP 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	62	7e-09
437	A2SQR0:HIS4_METLZ 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	62	1e-08
438	P05324:HIS4_METVA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	60	4e-08
439	Q8PWS2:HIS4_METMA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	59	6e-08
440	A0B7W4:HIS4_METTP 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	59	1e-07
441	Q50757:HIS4_METTL 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	59	1e-07
442	Q829J5:COBQ_STRAW Cobyric acid synthase - Streptomyces avermitilis	59	1e-07
443	Q8ESS1:HIS4_OCEIH 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	58	1e-07
444	P05325:HIS4_METVO 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	58	1e-07
445	Q58927:HIS4_METJA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	58	1e-07
446	Q3M7Q7:HIS4_ANAVT 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	58	2e-07
447	Q12WC6:HIS4_METBU 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	57	2e-07
448	Q8YNQ6:HIS4_ANASP 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	57	2e-07
449	Q9RJ20:COBQ_STRCO Cobyric acid synthase - Streptomyces coelicolor	57	4e-07
450	P74561:HIS4_SYNY3 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	55	8e-07
451	Q5ZW91:HIS4_LEGPH 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	55	1e-06
452	Q5X5X3:HIS4_LEGPA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	55	1e-06
453	Q2JK82:HIS4_SYNJB 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	55	1e-06
454	Q3IT10:HIS4_NATPD 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	54	2e-06
455	Q6NGL6:COBQ_CORDI Cobyric acid synthase - Corynebacterium diphth...	54	2e-06
456	A0LCF2:HIS4_MAGSM 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	53	5e-06
457	Q0I9E5:HIS4_SYNS3 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	51	2e-05
458	Q3A136:HIS4_PELCD 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	51	2e-05
459	Q5WX95:HIS4_LEGPL 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	51	2e-05
460	A1WW06:HIS4_HALHL 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	51	2e-05
461	Q3Z6V7:HIS4_DEHE1 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	50	3e-05
462	Q6AAP6:COBQ_PROAC Cobyric acid synthase - Propionibacterium acnes	50	3e-05
463	A2BW33:HIS4_PROM5 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	50	5e-05
464	Q9HN14:HIS4_HALSA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	50	5e-05
465	Q8Z5N6:COBQ_SALTI Cobyric acid synthase - Salmonella typhi	50	5e-05
466	Q3ZYM9:HIS4_DEHSC 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	49	6e-05
467	Q1GEZ5:HIS42_SILST 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamin...	49	6e-05
468	Q5YSA4:COBQ_NOCFA Cobyric acid synthase - Nocardia farcinica	49	6e-05
469	Q9A230:HIS4_CAUCR 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	49	8e-05
470	Q6NK10:PDXT_CORDI Glutamine amidotransferase subunit pdxT - Cory...	49	1e-04
471	Q73VS8:COBQ_MYCPA Cobyric acid synthase - Mycobacterium paratube...	49	1e-04
472	Q18DL2:HIS4_HALWD 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	48	1e-04
473	Q5UZH1:HIS4_HALMA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	48	1e-04
474	Q5WDI1:HIS4_BACSK 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	48	1e-04
475	Q05597:CBIP_SALTY Cobyric acid synthase - Salmonella typhimurium	48	1e-04
476	Q0BPX3:HIS4_GRABC 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	48	2e-04
477	Q89WM5:HIS4_BRAJA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	48	2e-04
478	Q98CT3:HIS4_RHILO 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	47	2e-04
479	Q97VZ9:GUAAA_SULSO GMP synthase [glutamine-hydrolyzing] subunit ...	47	2e-04
480	Q1MNC1:HIS4_RHIL3 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	47	3e-04
481	Q3SWF0:HIS4_NITWN 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	47	3e-04
482	Q7VC70:HIS4_PROMA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	47	4e-04
483	Q28NK3:HIS4_JANSC 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	46	5e-04
484	Q7NMQ9:HIS4_GLOVI 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	46	5e-04
485	Q8FY08:HIS4_BRUSU 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	46	5e-04
486	Q8YE36:HIS4_BRUME 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	46	5e-04
487	Q57AH4:HIS4_BRUAB 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	46	5e-04
488	Q2YQY9:HIS4_BRUA2 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	46	5e-04
489	Q2LVE9:HIS4_SYNAS 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	46	7e-04
490	Q03144:SNO1_YEAST Probable glutamine amidotransferase SNO1 - Sac...	45	9e-04
491	Q83GK3:PDXT_TROWT Glutamine amidotransferase subunit pdxT - Trop...	45	9e-04
492	Q83HM6:PDXT_TROW8 Glutamine amidotransferase subunit pdxT - Trop...	45	9e-04
493	Q3Z8V9:PDXT_DEHE1 Glutamine amidotransferase subunit pdxT - Deha...	45	9e-04
494	Q2KE60:HIS4_RHIEC 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	45	9e-04
495	Q7TUA7:HIS4_PROMP 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	45	9e-04
496	Q81ZV5:PDXT_STRAW Glutamine amidotransferase subunit pdxT - Stre...	45	0.001
497	Q6AFB8:PDXT_LEIXX Glutamine amidotransferase subunit pdxT - Leif...	45	0.001
498	Q57MR9:HIS4_SALCH 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	45	0.001
499	Q162Q2:HIS4_ROSDO 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino...	45	0.001
500	Q8LAD0:PDX2_ARATH Pyridoxal biosynthesis protein PDX2 - Arabidop...	45	0.001

>Q9SZ30:HIS5_ARATH Imidazole glycerol phosphate synthase hisHF, chloroplast precursor -|
            Arabidopsis thaliana (Mouse-ear cress)
          Length = 592
 Score =  848 bits (2192), Expect = 0.0
 Identities = 421/557 (75%), Positives = 480/557 (86%), Gaps = 1/557 (0%)
 Frame = +3

Query: 117  SVGRSKRTNQRRRPASLSVRASGDANTV-TLLDYGAGNVRSVRNAIRHLGFNIRDVRSPE 293
            S+G   R  + + P SLSVRAS  +++V TLLDYGAGNVRS+RNA+RHLGF+I+DV++P 
Sbjct: 38   SIGNVNR--KFKSPRSLSVRASSTSDSVVTLLDYGAGNVRSIRNALRHLGFSIKDVQTPG 95

Query: 294  DILAADRLVFPGVGAFGSAMDVLNRTGMADALREYIRMDRPFLGICLGLQLLFDSSEENG 473
            DIL ADRL+FPGVGAF  AMDVLNRTGMA+AL +YI  DRPFLGICLGLQLLFDSSEENG
Sbjct: 96   DILNADRLIFPGVGAFAPAMDVLNRTGMAEALCKYIENDRPFLGICLGLQLLFDSSEENG 155

Query: 474  PVSGLGVIPGVVRRFDSSEGLIVPHIGWNALQITKDTQLLQGADGQHVYFVHSYHALPSD 653
            PV GLGVIPG+V RFD+S G+ VPHIGWNALQ+ KD+++L     +HVYFVHSY A+PSD
Sbjct: 156  PVKGLGVIPGIVGRFDASAGIRVPHIGWNALQVGKDSEILDDVGNRHVYFVHSYRAIPSD 215

Query: 654  ANKDWISLTCNYGESFISSISMGNIQAVQFHPEKSGATGLNIFENFLSPNSSGAKAPARR 833
             NKDWIS TCNYGESFISSI  GN+ AVQFHPEKSG  GL++   FL P     + P   
Sbjct: 216  ENKDWISSTCNYGESFISSIRRGNVHAVQFHPEKSGEVGLSVLRRFLHPKLPATQKPMEG 275

Query: 834  KASKLAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGA 1013
            KASKLAKRVIACLDVR+ND GDLVVTKGDQYDVR+ S+  EVRNLGKPV+LA QYY DGA
Sbjct: 276  KASKLAKRVIACLDVRTNDKGDLVVTKGDQYDVREQSNENEVRNLGKPVDLAGQYYKDGA 335

Query: 1014 DEVSFLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVAS 1193
            DE+SFLNITGFR FPLGDLPM++VLR  S+ VFVPLTVGGGIRDFTD SGRYYSSLEVA+
Sbjct: 336  DEISFLNITGFRDFPLGDLPMIQVLRQTSKNVFVPLTVGGGIRDFTDASGRYYSSLEVAA 395

Query: 1194 EYFRSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKS 1373
            EYFRSGADKISIGSDAV AAE ++++GVKTGKSSLEQISRVYGNQAVVVSIDPRRVYV  
Sbjct: 396  EYFRSGADKISIGSDAVSAAEEFIKSGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVNH 455

Query: 1374 PDEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCID 1553
            PD+V ++ ++V++ GP GEEYAWYQCTVSGGR+ RPIGA+ELAKAVEELGAGEILLNCID
Sbjct: 456  PDDVPYKVIRVTNPGPNGEEYAWYQCTVSGGREGRPIGAFELAKAVEELGAGEILLNCID 515

Query: 1554 CDGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVP 1733
            CDGQG GFDIDL+K++SD+V IPVIASSGAG  +HFSEVFEKTNASAALAAGIFHRKEVP
Sbjct: 516  CDGQGKGFDIDLVKLISDSVGIPVIASSGAGTPDHFSEVFEKTNASAALAAGIFHRKEVP 575

Query: 1734 ILAVKEHLVDAGVEVRM 1784
            I +VKEHL +  +EVR+
Sbjct: 576  IQSVKEHLQEERIEVRI 592

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>O94303:HIS5_SCHPO Imidazole glycerol phosphate synthase hisHF - Schizosaccharomyces|
            pombe (Fission yeast)
          Length = 541

 Score =  544 bits (1401), Expect = e-154
 Identities = 288/543 (53%), Positives = 372/543 (68%), Gaps = 15/543 (2%)
 Frame = +3

Query: 198  VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
            V+++DYG+GNVRS+ NA+R+LGF  + +R+P DI  A+ L+FPGVG FG   D L + G 
Sbjct: 3    VSIVDYGSGNVRSLINAVRYLGFETQWIRNPHDIEKAECLIFPGVGNFGFVCDSLAKQGF 62

Query: 378  ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
             + LR Y    +PF+ +C+G+Q LF+ S E     GLGV PG+V+RFD+ +   VPHIGW
Sbjct: 63   LEPLRRYALSGKPFMAVCVGIQALFEGSVEAPHSKGLGVFPGLVQRFDNDDKT-VPHIGW 121

Query: 558  NALQITKDT--QLLQGADGQHVYFVHSYHALPSDA---NKDWISLTCNYG-ESFISSISM 719
            N+  +  DT  +          YFVHSY  +P        ++   T  YG E+F+ +I  
Sbjct: 122  NSCAVRSDTSKEFFGMRPHDKFYFVHSY-MIPEKGLILPPEFKIATTKYGNETFVGAIVK 180

Query: 720  GNIQAVQFHPEKSGATGLNIFENFLSPNSSGAKAPARRKASKL--------AKRVIACLD 875
             N  A QFHPEKSG+ GL   + FL+ N    + P   +ASKL         KR+IACLD
Sbjct: 181  NNFLATQFHPEKSGSAGLRCLKAFLTGNY---EQPISGEASKLIENSFGGLTKRIIACLD 237

Query: 876  VRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVSFLNITGFRAF 1055
            VRSND GDLVVTKGDQYDVR+ SS  EVRNLGKPVEL  +Y+ +GADEV FLNIT FR  
Sbjct: 238  VRSNDAGDLVVTKGDQYDVREKSSGSEVRNLGKPVELCQRYFQEGADEVVFLNITSFRNC 297

Query: 1056 PLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRSGADKISIGS 1235
            P+ D PML+VL  A++ VFVPLTVGGGIRD +D  G ++ ++EVA  YFRSGADK+SIGS
Sbjct: 298  PMADAPMLQVLEKAAQTVFVPLTVGGGIRDVSDPDGTFHPAVEVAGIYFRSGADKVSIGS 357

Query: 1236 DAVFAAEAYLQTGVK-TGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQFRTVKVSS 1412
            DAV+AAE Y + G K +GK+++E IS+ YGNQAVV+S+DP+R YVK P++ +   VK S 
Sbjct: 358  DAVYAAEKYYENGKKLSGKTAIETISKAYGNQAVVISVDPKRQYVKVPEDTKHHVVKTSR 417

Query: 1413 KGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQGGGFDIDLI 1592
             GP GE Y WYQCTV GGR+ R I   EL +A E +GAGE+LLNC+D DG   G+DI+L+
Sbjct: 418  LGPNGEAYCWYQCTVKGGREYRDIDVVELTRACEAMGAGEVLLNCMDQDGSNAGYDIELV 477

Query: 1593 KMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVKEHLVDAGV 1772
            ++V ++V IPVIASSGAG  +HF EVF++T+  AALAAGIFHR+   I  VKE+L    V
Sbjct: 478  RLVKNSVNIPVIASSGAGIPQHFEEVFKETDCDAALAAGIFHRQTCRIEDVKEYLAIHDV 537

Query: 1773 EVR 1781
             VR
Sbjct: 538  LVR 540

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>Q9P4P9:HIS5_EMENI Imidazole glycerol phosphate synthase hisHF - Emericella nidulans|
            (Aspergillus nidulans)
          Length = 553

 Score =  527 bits (1357), Expect = e-149
 Identities = 287/550 (52%), Positives = 367/550 (66%), Gaps = 21/550 (3%)
 Frame = +3

Query: 195  TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTG 374
            TV LLDY AGNVRS+ NAI  +G+ +  VRSP D+   ++L+ PGVG FG  +  L+  G
Sbjct: 3    TVHLLDYVAGNVRSLVNAINKVGYEVEWVRSPSDLKDVEKLILPGVGHFGHCLSQLSSGG 62

Query: 375  MADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIG 554
                +RE+I   +PF+GIC+GLQ LF+SSEE+  + GLG IP  +R+FD+     VPHIG
Sbjct: 63   YLQPIREHIASGKPFMGICVGLQSLFESSEEDPNIPGLGTIPARLRKFDAKTKS-VPHIG 121

Query: 555  WNALQITK----DTQLLQG-ADGQHVYFVHSYHAL--PSDANKD-WISLTCNYGES-FIS 707
            WN+   T+      Q   G +     Y+VHSY A   P    KD W+  T +YGE  FI 
Sbjct: 122  WNSATDTRIDSTGGQTFYGLSPSSKYYYVHSYAAPYEPGILEKDGWLVATASYGEEKFIG 181

Query: 708  SISMGNIQAVQFHPEKSGATGLNIFENFLSPNSSGAKAPA--------RRKASKLAKRVI 863
            +I+  NI A QFHPEKSG  GL     FL     GA+  +          + + L +R+I
Sbjct: 182  AIARDNIFATQFHPEKSGQAGLRTLRAFLD----GAQLHSVTLEDSILTGEKNGLTRRII 237

Query: 864  ACLDVRSNDNGDLVVTKGDQYDVRDHSSSK---EVRNLGKPVELASQYYIDGADEVSFLN 1034
            ACLDVR+ND GDLVVTKGDQYDVR+   +    +VRNLGKPV++A +YY  GADEV+FLN
Sbjct: 238  ACLDVRTNDVGDLVVTKGDQYDVREKDGADAGGQVRNLGKPVDMAKKYYEQGADEVTFLN 297

Query: 1035 ITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRSGA 1214
            IT FR  PL DLPMLE+LR  SE VFVPLT+GGGIRD  D  G +  +L+VAS YF+SGA
Sbjct: 298  ITSFRNCPLADLPMLEILRRTSETVFVPLTIGGGIRDTVDTDGTHIPALDVASMYFKSGA 357

Query: 1215 DKISIGSDAVFAAEAYLQTG-VKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQF 1391
            DK+SIGSDAV AAE Y   G V +GK+++E IS+ YGNQAVVVS+DP+RVYV  P++ + 
Sbjct: 358  DKVSIGSDAVVAAEDYYAAGKVLSGKTAIETISKAYGNQAVVVSVDPKRVYVSQPEDTKH 417

Query: 1392 RTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQGG 1571
            RT++       G+ + WYQCT+ GGR++R +   +L +AVE +GAGEILLNCID DG   
Sbjct: 418  RTIETKFPNAAGQNFCWYQCTIKGGRETRDLDVCQLVQAVEAMGAGEILLNCIDKDGSNS 477

Query: 1572 GFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVKE 1751
            GFD++LI  V  AV IPVIASSGAG  +HF EVF++T   AAL AG+FHR E  +  VK+
Sbjct: 478  GFDLELINHVKAAVKIPVIASSGAGMPKHFEEVFDQTTTDAALGAGMFHRGEYTVGEVKQ 537

Query: 1752 HLVDAGVEVR 1781
            +L D G  VR
Sbjct: 538  YLEDRGFLVR 547

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>P33734:HIS5_YEAST Imidazole glycerol phosphate synthase hisHF - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 552

 Score =  520 bits (1340), Expect = e-147
 Identities = 286/549 (52%), Positives = 364/549 (66%), Gaps = 20/549 (3%)
 Frame = +3

Query: 198  VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPED--ILAADRLVFPGVGAFGSAMDVLNRT 371
            V ++D  +GN++S+ NAI HLG+ ++ V+SP+D  I    RL+ PGVG +G  +D L   
Sbjct: 4    VHVIDVESGNLQSLTNAIEHLGYEVQLVKSPKDFNISGTSRLILPGVGNYGHFVDNLFNR 63

Query: 372  GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHI 551
            G    +REYI   +P +GIC+GLQ LF  S E+   +GL  I   + RFD SE   VP I
Sbjct: 64   GFEKPIREYIESGKPIMGICVGLQALFAGSVESPKSTGLNYIDFKLSRFDDSEKP-VPEI 122

Query: 552  GWNALQITKDTQLLQGADG-QHVYFVHSYHALPSDANKD------WISLTCNYG-ESFIS 707
            GWN+   +++  L  G D  +  YFVHS+ A+ +   K       W      YG E FI+
Sbjct: 123  GWNSCIPSEN--LFFGLDPYKRYYFVHSFAAILNSEKKKNLENDGWKIAKAKYGSEEFIA 180

Query: 708  SISMGNIQAVQFHPEKSGATGLNIFENFLS------PNSSGAKAPARRKASK---LAKRV 860
            +++  NI A QFHPEKSG  GLN+ ENFL       PN S  +            L +R+
Sbjct: 181  AVNKNNIFATQFHPEKSGKAGLNVIENFLKQQSPPIPNYSAEEKELLMNDYSNYGLTRRI 240

Query: 861  IACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVSFLNIT 1040
            IACLDVR+ND GDLVVTKGDQYDVR+ S  K VRNLGKPV+LA +YY  GADEV+FLNIT
Sbjct: 241  IACLDVRTNDQGDLVVTKGDQYDVREKSDGKGVRNLGKPVQLAQKYYQQGADEVTFLNIT 300

Query: 1041 GFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRSGADK 1220
             FR  PL D PMLEVL+ A++ VFVPLTVGGGI+D  D  G    +LEVAS YFRSGADK
Sbjct: 301  SFRDCPLKDTPMLEVLKQAAKTVFVPLTVGGGIKDIVDVDGTKIPALEVASLYFRSGADK 360

Query: 1221 ISIGSDAVFAAEAYLQTGVK-TGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQFRT 1397
            +SIG+DAV+AAE Y + G +  G S +E IS+ YG QAVV+S+DP+RVYV S  + + + 
Sbjct: 361  VSIGTDAVYAAEKYYELGNRGDGTSPIETISKAYGAQAVVISVDPKRVYVNSQADTKNKV 420

Query: 1398 VKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQGGGF 1577
             +    GP GE+Y WYQCT+ GGR+SR +G +EL +A E LGAGEILLNCID DG   G+
Sbjct: 421  FETEYPGPNGEKYCWYQCTIKGGRESRDLGVWELTRACEALGAGEILLNCIDKDGSNSGY 480

Query: 1578 DIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVKEHL 1757
            D++LI+ V DAV IPVIASSGAG  EHF E F KT A A L AG+FHR E  +  VKE+L
Sbjct: 481  DLELIEHVKDAVKIPVIASSGAGVPEHFEEAFLKTRADACLGAGMFHRGEFTVNDVKEYL 540

Query: 1758 VDAGVEVRM 1784
            ++ G++VRM
Sbjct: 541  LEHGLKVRM 549

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>Q8TYW8:HIS6_METKA Imidazole glycerol phosphate synthase subunit hisF - Methanopyrus|
            kandleri
          Length = 272

 Score =  192 bits (487), Expect = 6e-48
 Identities = 129/312 (41%), Positives = 175/312 (56%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV+     D  V KG ++        + +R+ G P ELA  YY  GADE+ 
Sbjct: 3    LAKRIIPCLDVK-----DGRVVKGVRF--------RGLRDAGDPAELAHHYYRHGADEIV 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   A P G   M++V+R  +EKVF+P+TVGGGI D  D                 
Sbjct: 50   FLDIS---ASPEGRRLMVDVVRRTAEKVFIPMTVGGGISDVED-----------FRRALT 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + AV   E             + + + ++G+Q VVV+ID +R  +K   E 
Sbjct: 96   AGADKVSVNTAAVENPEL------------ISEAADIFGSQCVVVAIDAKREPLKPEHEH 143

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                +  +  G    EY W++  V GGR+   + A   AK VEELGAGEILL  ID DG 
Sbjct: 144  VADHIFSNDDG----EY-WFRVYVRGGREPVDLDAITWAKRVEELGAGEILLTSIDADGT 198

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI+L + V +AV+IPVIAS G G  +H  EVF++ +A AALAA IFH  +  I  V
Sbjct: 199  QEGYDIELTREVCNAVSIPVIASGGCGHPKHMVEVFKEADADAALAASIFHYGKFTIEEV 258

Query: 1746 KEHLVDAGVEVR 1781
            KEHL + GV VR
Sbjct: 259  KEHLAERGVRVR 270

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>O29439:HIS6_ARCFU Imidazole glycerol phosphate synthase subunit hisF - Archaeoglobus|
            fulgidus
          Length = 271

 Score =  189 bits (480), Expect = 4e-47
 Identities = 125/313 (39%), Positives = 174/313 (55%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV + D  +  V KG ++          +R+ G PVELA +Y  +GADE+ 
Sbjct: 2    LAKRIIPCLDV-TLDESEARVVKGVEF--------VNLRDAGDPVELAKRYDEEGADELV 52

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A P G   M++V+   +E+VF+P TVGGGI+           S+E  +    
Sbjct: 53   FLDIT---ASPEGRRTMIDVIERTAEQVFIPFTVGGGIK-----------SIEDINTILS 98

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV   E             + + + ++G+Q +VV+ID RR +  S  E 
Sbjct: 99   AGADKVSINTAAVKNPEF------------VREAADIFGSQCIVVAIDCRRNFDLSKGEY 146

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                   +         AWY+  + GGR    I A   AK VEELGAGEILL  ++ DG 
Sbjct: 147  IVELEDGTK--------AWYEVVIYGGRKPVGIDAVWWAKRVEELGAGEILLTSMNRDGT 198

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI + + +S+ V IPVIAS GAG  EHF E F +  A A LAA IFH +E+ I  +
Sbjct: 199  KDGFDIPITRKISEEVNIPVIASGGAGTKEHFYEGFVEGKADACLAASIFHYREIGIREI 258

Query: 1746 KEHLVDAGVEVRM 1784
            KE+L + GV+VR+
Sbjct: 259  KEYLAERGVQVRL 271

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>O27398:HIS6_METTH Imidazole glycerol phosphate synthase subunit hisF - Methanobacterium|
            thermoautotrophicum
          Length = 274

 Score =  186 bits (473), Expect = 2e-46
 Identities = 125/314 (39%), Positives = 170/314 (54%), Gaps = 1/314 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSN-DNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEV 1022
            LAKR+I CLD      NG +V  KG ++        K++R  G PVELA++YY DGADE+
Sbjct: 2    LAKRIIPCLDCDLQVPNGRVV--KGVEF--------KQIRYAGDPVELATRYYEDGADEI 51

Query: 1023 SFLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYF 1202
             FL+IT           M  V+   +E VFVP+ VGGGIR   D    Y+  L       
Sbjct: 52   VFLDITASHE---RRETMTHVIEATTENVFVPICVGGGIRKPED----YFKML------- 97

Query: 1203 RSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDE 1382
            ++GADK S  + A+   E             + + S + G+QA VV+ID +R Y+++P E
Sbjct: 98   KAGADKCSTNTAAIKNPEL------------INEASDLVGSQACVVAIDAKRRYIENPRE 145

Query: 1383 VQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDG 1562
               R +     G     Y WY+C++ GGR+   I A + A   ++ GAGEILL  +D DG
Sbjct: 146  SDERFIIEVDDG-----YCWYECSIYGGREFTGIDAVKWAMECQDRGAGEILLTSMDRDG 200

Query: 1563 QGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILA 1742
               G+DI L + +S+ + IPVIAS G G  EH  E F    A AALAA IFH  E P+ A
Sbjct: 201  TKMGYDIPLTRTMSENLDIPVIASGGVGEPEHIYEAFTDGKADAALAASIFHFNEYPVPA 260

Query: 1743 VKEHLVDAGVEVRM 1784
            VKE+L   GV +R+
Sbjct: 261  VKEYLRSRGVPIRL 274

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>Q5V2C9:HIS6_HALMA Imidazole glycerol phosphate synthase subunit hisF - Haloarcula|
            marismortui (Halobacterium marismortui)
          Length = 271

 Score =  186 bits (471), Expect = 4e-46
 Identities = 119/313 (38%), Positives = 163/313 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I C+DV  ++NGD  V  G  ++  +++        G PVE+A  Y   GADE  
Sbjct: 3    LTKRIIPCIDVDVDENGDAAVYTGVNFEDLEYT--------GDPVEMAKAYNESGADEFV 54

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   ML+ +   +++VF+PLTVGGGIR   D             E  R
Sbjct: 55   FLDIT---ASAEGRETMLDTVSAVADEVFIPLTVGGGIRTRAD-----------IKETLR 100

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S A+  AE  L          + + +  +G+Q +V+S+D RR +    +  
Sbjct: 101  AGADKVSINSGAI--AEPDL----------INEGAAAFGSQCIVISVDARRRFDSEGEHY 148

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                        +  E  W++CTV GGR+   +   E A   EE GAGE+ +N ID DG 
Sbjct: 149  T----------EVDGESCWFECTVKGGREGTGLDVIEWATEAEERGAGELFVNSIDADGT 198

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L+K V D V+ PVIASSG G+ E   EVF    A A LAA IFH  E  I   
Sbjct: 199  KDGYDIPLMKAVCDTVSTPVIASSGCGSPEDMEEVFVDAGADAGLAASIFHFGEYSIAET 258

Query: 1746 KEHLVDAGVEVRM 1784
            KE+L   G+ VR+
Sbjct: 259  KEYLDSKGIPVRL 271

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>P60666:HIS6_MYCPA Imidazole glycerol phosphate synthase subunit hisF - Mycobacterium|
            paratuberculosis
          Length = 265

 Score =  185 bits (469), Expect = 7e-46
 Identities = 127/331 (38%), Positives = 177/331 (53%)
 Frame = +3

Query: 792  LSPNSSGAKAPARRKASKLAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLG 971
            +SPNS+G           LA RVI CLDV   D+G +V  KG  ++         +R+ G
Sbjct: 1    MSPNSTG-----------LAVRVIPCLDV---DDGRVV--KGVNFE--------NLRDAG 36

Query: 972  KPVELASQYYIDGADEVSFLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFT 1151
             PVELA+ Y  +GADE++FL++T   A   G   ML+V+R  +E+VF+PLTVGGG+R   
Sbjct: 37   DPVELAAVYDAEGADELTFLDVT---ASSSGRATMLDVVRRTAEQVFIPLTVGGGVRTVA 93

Query: 1152 DESGRYYSSLEVASEYFRSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQA 1331
            D                R+GADK+S+ + A+   E             LE+++R +G+Q 
Sbjct: 94   D-----------VDVLLRAGADKVSVNTAAIARPEL------------LEEMARQFGSQC 130

Query: 1332 VVVSIDPRRVYVKSPDEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAV 1511
            +V+S+D R V                  G +     W + T  GGR    I A E A   
Sbjct: 131  IVLSVDARTV----------------PPGAVPTPSGW-EVTTHGGRRGTGIDAVEWASRG 173

Query: 1512 EELGAGEILLNCIDCDGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNAS 1691
             +LG GEILLN +D DG   GFD+++++ V  AVT+PVIAS GAGA EHF+   E   A 
Sbjct: 174  ADLGVGEILLNSMDADGTKAGFDLEMLQAVRSAVTVPVIASGGAGAAEHFAPAIE-AGAD 232

Query: 1692 AALAAGIFHRKEVPILAVKEHLVDAGVEVRM 1784
            A LAA +FH +E+ I  VK  + +AG+ VRM
Sbjct: 233  AVLAASVFHFRELTIGQVKAAMAEAGIPVRM 263

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>Q57854:HIS6_METJA Imidazole glycerol phosphate synthase subunit hisF - Methanococcus|
            jannaschii
          Length = 272

 Score =  184 bits (468), Expect = 9e-46
 Identities = 122/315 (38%), Positives = 172/315 (54%), Gaps = 2/315 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLD++     D  V KG ++          +R+ G PVELA  Y  +GADE+ 
Sbjct: 2    LTKRIIPCLDIK-----DGRVVKGTKF--------LNLRDAGDPVELAQYYDDEGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D+ +++V+   +EKVF+PLTVGGGI+           S+E      R
Sbjct: 49   FLDITA--SAEKRDI-IIDVVERTAEKVFIPLTVGGGIK-----------SIEDFRRILR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSP--D 1379
            +GADK+SI + AV               + +++ S ++G+Q VVV+ID +R YV     D
Sbjct: 95   AGADKVSINTAAV------------KNPNLIKEASEIFGSQCVVVAIDAKRHYVNEDEID 142

Query: 1380 EVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCD 1559
            ++    VKV       + Y W++  + GGR    I A   AK VEELGAGEILL  ID D
Sbjct: 143  KINKNVVKVE------DGYCWFEVYIYGGRKETGIDAINWAKKVEELGAGEILLTSIDKD 196

Query: 1560 GQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPIL 1739
            G   G+D+ L K +S +V +PVIAS G G  EH  E F    A AAL AGI H +E  I 
Sbjct: 197  GTKSGYDLILTKEISKSVKLPVIASGGCGKPEHVYEAFVYGKADAALMAGILHYREYTIE 256

Query: 1740 AVKEHLVDAGVEVRM 1784
             +K++  D G+ +R+
Sbjct: 257  EIKKYCADRGIPMRL 271

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>Q3INY2:HIS6_NATPD Imidazole glycerol phosphate synthase subunit hisF - Natronomonas|
            pharaonis (strain DSM 2160 / ATCC 35678)
          Length = 271

 Score =  183 bits (465), Expect = 2e-45
 Identities = 118/313 (37%), Positives = 165/313 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I C+DV  N++G+  V  G  ++  +++        G PVELA +Y   GADE  
Sbjct: 3    LTKRIIPCIDVDLNEDGEAAVYTGVNFEDLEYT--------GDPVELAKKYNEAGADEFV 54

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   ML+ +   +++ F+PLTVGGGIR   D             E  R
Sbjct: 55   FLDIT---ASAEGRETMLDTVSAVADECFIPLTVGGGIRTRDD-----------IKETLR 100

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + A+   E             + + +  +G+Q +V+S+D RR +    DE 
Sbjct: 101  AGADKVSINTGALQRPEL------------IGEGAEAFGSQCIVISVDARRRF----DEA 144

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                V+V        E  W++CT+ GGR+       E A    + GAGE+ +N ID DG 
Sbjct: 145  GEHYVEVDG------ESCWFECTIKGGREGTGTDVVEWAGEAADRGAGELFVNSIDADGT 198

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L K V D V  PVIASSG G+ EH +EVFE  +A AALAA IFH +E  I   
Sbjct: 199  KDGYDIPLTKAVCDNVPTPVIASSGCGSPEHMAEVFEDADADAALAASIFHFEEYSIEET 258

Query: 1746 KEHLVDAGVEVRM 1784
            K  L + G+ VR+
Sbjct: 259  KRSLDEQGIPVRL 271

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>Q4JW52:HIS6_CORJK Imidazole glycerol phosphate synthase subunit hisF - Corynebacterium|
            jeikeium (strain K411)
          Length = 260

 Score =  183 bits (464), Expect = 3e-45
 Identities = 130/310 (41%), Positives = 173/310 (55%)
 Frame = +3

Query: 855  RVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVSFLN 1034
            RVI CLDV   DNG +V  KG  ++         +R+ G PVELA +Y   GADE++FL+
Sbjct: 6    RVIPCLDV---DNGRVV--KGVNFE--------GLRDAGDPVELAKRYDALGADELTFLD 52

Query: 1035 ITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRSGA 1214
            ++  +    G   ML+V+R  +++VF+PLTVGGG+R           S E      R+GA
Sbjct: 53   VSASKD---GRGTMLDVVRHTADQVFIPLTVGGGVR-----------SEEDVDALLRAGA 98

Query: 1215 DKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQFR 1394
            DK+S+ S AV   E             L ++S+ +G Q +V+S+D RRV  K P E    
Sbjct: 99   DKVSVNSSAVARPEL------------LRELSQRFGAQCIVLSVDARRV--KDPVE---- 140

Query: 1395 TVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQGGG 1574
                + K P G     ++ T  GG  S  + A E A+  EELG GEILLN +D DG   G
Sbjct: 141  ----ADKYPSG-----FEVTTHGGTKSAGLDAIEWARKGEELGVGEILLNSMDGDGTKAG 191

Query: 1575 FDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVKEH 1754
            FDI++++ V  AV+IPVIAS GAGA +HF    E   A A LAA IFH  EV I  VK+ 
Sbjct: 192  FDIEMLQAVRKAVSIPVIASGGAGAPDHFPPAVE-AGADAVLAASIFHFGEVEIREVKQA 250

Query: 1755 LVDAGVEVRM 1784
            L DAG EVR+
Sbjct: 251  LADAGYEVRL 260

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>Q3A135:HIS5_PELCD Imidazole glycerol phosphate synthase subunit hisH - Pelobacter|
           carbinolicus (strain DSM 2380 / Gra Bd 1)
          Length = 206

 Score =  181 bits (460), Expect = 8e-45
 Identities = 92/204 (45%), Positives = 125/204 (61%), Gaps = 6/204 (2%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+RSV+     +G++ R    P  +  AD+LV PGVGAF   MD L   G 
Sbjct: 2   IVIIDYGMGNLRSVQKGFEKVGYSARVTDDPAVVAQADKLVLPGVGAFRDCMDQLTAGGF 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEGLIV 542
            + +  ++   RPFLGICLGLQLLF  SEE G   GL +IPG V RF     +  E L V
Sbjct: 62  VEPILRHVESGRPFLGICLGLQLLFTESEEFGHHQGLNIIPGRVVRFPGDMQEQGEVLKV 121

Query: 543 PHIGWNALQITKDTQLLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISM 719
           PH+GWN + I +   + QG D G+ VYFVHSY+ +P DA+   ++ T +YG +F +++  
Sbjct: 122 PHMGWNQIDIQRPAPIFQGLDSGESVYFVHSYYVVPEDASV--VAATADYGRTFCAAVWR 179

Query: 720 GNIQAVQFHPEKSGATGLNIFENF 791
            N+ A QFHPEKS   GL I +NF
Sbjct: 180 DNVMATQFHPEKSQQVGLRILKNF 203

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>Q9HR52:HIS6_HALSA Imidazole glycerol phosphate synthase subunit hisF - Halobacterium|
            salinarium (Halobacterium halobium)
          Length = 273

 Score =  180 bits (457), Expect = 2e-44
 Identities = 118/312 (37%), Positives = 165/312 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KRVI C+DV  +D+G+  V  G  ++        E+   G PVE+A +Y   GADE  
Sbjct: 3    LTKRVIPCIDVDLDDDGEPAVYTGVNFE--------ELAYTGDPVEMAKRYNEAGADEFV 54

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   ML+ +   +++VF+PLTVGGGIRD  D             E  R
Sbjct: 55   FLDIT---ASAEGRETMLDTVSAVADEVFIPLTVGGGIRDTDD-----------IRETLR 100

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S A+               S +++ ++ +G+Q +V+S+D RR +    DE 
Sbjct: 101  AGADKVSINSGAI------------ADPSLVDRGAKAFGSQCIVISVDARRRF----DEQ 144

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                 +V        E  W++CTV GGR+   + A E  +  +  GAGE+ +N ID DG 
Sbjct: 145  GQHYTQVDG------ESCWFECTVHGGREGTGMDAIEWVQEAQRRGAGELFVNSIDADGT 198

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L   V DAV+ PVIASSG GA    ++ ++   A AALAA IFH  E  I   
Sbjct: 199  QDGYDVPLTAAVCDAVSTPVIASSGCGAPGDMADAYD-AGADAALAASIFHFDEYSIAET 257

Query: 1746 KEHLVDAGVEVR 1781
            KE L DAG  +R
Sbjct: 258  KETLADAGYPIR 269

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>Q8R885:HIS6_THETN Imidazole glycerol phosphate synthase subunit hisF -|
            Thermoanaerobacter tengcongensis
          Length = 253

 Score =  179 bits (455), Expect = 3e-44
 Identities = 123/313 (39%), Positives = 172/313 (54%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV+     D  V KG  +          +++ G PVE+A +Y   GADE+ 
Sbjct: 2    LAKRIIPCLDVK-----DGRVVKGINF--------VNLKDAGDPVEIAERYNELGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   ++    + M++V++  SEKVF+PLTVGGGI D  D             E  +
Sbjct: 49   FLDITA--SYEKRKI-MIDVVKRTSEKVFIPLTVGGGISDIDD-----------IREVLK 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV       Q  ++            +G+Q VVV+ID +          
Sbjct: 95   AGADKVSINTQAVKQPTLIRQAALR------------FGSQCVVVAIDAK---------- 132

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                     K P G  Y  Y   ++GGR +  + A E AK V++LGAGEILL  +D DG 
Sbjct: 133  ---------KRPDGTGYNVY---INGGRINTGLDAVEWAKKVKDLGAGEILLTSMDKDGT 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI+L +++S+AV+IPVIAS GAG  EHF EVF +  A AALAA +FH  E+ I  +
Sbjct: 181  KDGYDIELTRLISEAVSIPVIASGGAGKPEHFKEVFTQGKADAALAASVFHYGELDIKEL 240

Query: 1746 KEHLVDAGVEVRM 1784
            K +L D G+ VR+
Sbjct: 241  KRYLKDEGIPVRL 253

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>O31139:HIS6_CORGL Imidazole glycerol phosphate synthase subunit hisF - Corynebacterium|
            glutamicum (Brevibacterium flavum)
          Length = 258

 Score =  179 bits (453), Expect = 5e-44
 Identities = 125/312 (40%), Positives = 172/312 (55%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A RVI CLDV   DNG +V  KG  ++         +R+ G PVELA +Y  +GADE++
Sbjct: 3    VAIRVIPCLDV---DNGRVV--KGVNFE--------NLRDAGDPVELAKRYDEEGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL++T  +    G   ML+V+R  +++VF+PLTVGGG+R           S E   +  R
Sbjct: 50   FLDVTASKH---GRGTMLDVVRRTADQVFIPLTVGGGVR-----------SEEDVDQLLR 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + A+   E             L ++S+ +G Q +V+S+D RRV        
Sbjct: 96   AGADKVSVNTSAIARPEL------------LSELSKRFGAQCIVLSVDARRV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                 +  +  P G     ++ T  GG  S  + A E AK  EELG GEILLN +D DG 
Sbjct: 136  ----PEGGTPQPSG-----FEVTTHGGSKSAELDAIEWAKRGEELGVGEILLNSMDGDGT 186

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD++L++ V  AV+IPVIAS GAG  EHF        A+A LAA IFH +EV I  V
Sbjct: 187  KNGFDLELLEKVRAAVSIPVIASGGAGKAEHFPPAV-AAGANAVLAATIFHFREVTIAEV 245

Query: 1746 KEHLVDAGVEVR 1781
            K  + DAG EVR
Sbjct: 246  KGAIKDAGFEVR 257

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>O66567:HIS6_AQUAE Imidazole glycerol phosphate synthase subunit hisF - Aquifex aeolicus|
          Length = 253

 Score =  177 bits (448), Expect = 2e-43
 Identities = 125/312 (40%), Positives = 170/312 (54%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   D G +V  KG ++          +R+ G PVE+A +Y  +GADE+ 
Sbjct: 2    LAKRIIPCLDV---DKGRVV--KGVKF--------LNLRDAGDPVEVAKRYEEEGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       M++V++  +E VF+P TVGGGIR           SLE       
Sbjct: 49   FLDIT---ASAEDREIMIDVVKKVAETVFMPFTVGGGIR-----------SLEDMRRLLE 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKISI + AV               + + + ++ +G+Q +VV+ID +R         
Sbjct: 95   AGADKISINTAAV------------KNPNLIYEGAKRFGSQCIVVAIDAKR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                     KG   E Y      + GGR    + A E AK VE LGAGEILL  +D DG 
Sbjct: 134  ---------KGNSWEVY------IHGGRTPTGLDAVEWAKKVESLGAGEILLTSMDRDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI+L + +S+AV IPVIAS GAG  EHF EVF KT   AALAA +FH +E+ I  +
Sbjct: 179  KDGYDIELNRAISEAVNIPVIASGGAGKKEHFYEVFSKTKVEAALAASVFHFREISIPEL 238

Query: 1746 KEHLVDAGVEVR 1781
            KE+L++ G+ VR
Sbjct: 239  KEYLLERGINVR 250

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>O27568:HIS5_METTH Imidazole glycerol phosphate synthase subunit hisH -|
           Methanobacterium thermoautotrophicum
          Length = 198

 Score =  176 bits (447), Expect = 2e-43
 Identities = 95/199 (47%), Positives = 128/199 (64%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG+GN+RS+ NA R +G +      P+ + AAD LV PGVGAFGSAM  L   G+
Sbjct: 2   IAIIDYGSGNLRSIANAFRKIGADALVTSDPQILEAADALVLPGVGAFGSAMAKLE--GL 59

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + L   I   +PFLGICLGLQ+L   S+E+  V GL +IPG V R     G  VPH+GW
Sbjct: 60  RETLLGNIMDGKPFLGICLGLQVLLSESQESPGVHGLDLIPGRVIRI--PPGNKVPHMGW 117

Query: 558 NALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQAV 737
           N L I +D+QLL+GA+ ++ YFVHSY+A PS+   D +    +YG    ++I   NI A 
Sbjct: 118 NQLIIVEDSQLLEGAEDEYFYFVHSYYAEPSN---DVVVARTDYGVEMTAAIESDNIHAT 174

Query: 738 QFHPEKSGATGLNIFENFL 794
           QFHPEKSG  GL++  NF+
Sbjct: 175 QFHPEKSGEAGLDVLRNFV 193

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>Q8TT96:HIS6_METAC Imidazole glycerol phosphate synthase subunit hisF - Methanosarcina|
            acetivorans
          Length = 273

 Score =  176 bits (446), Expect = 3e-43
 Identities = 116/315 (36%), Positives = 173/315 (54%), Gaps = 2/315 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV  +  G  VV KG ++         +++  G PVELA +Y  DGADE+ 
Sbjct: 2    LTKRIIPCLDVTLDRAGGCVV-KGVEF--------VDLKEAGDPVELAKRYNEDGADELV 52

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   M++V+   +++VF+PLTVGGGI           SS++   +  R
Sbjct: 53   FLDIT---ASAHGRETMIDVIERTADEVFIPLTVGGGI-----------SSIDAIRQILR 98

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRV--YVKSPD 1379
            +GADK+S+ + AV                 +++ S ++G Q +V +ID RR      +PD
Sbjct: 99   AGADKVSVNTSAV------------KNPDFIKESSDIFGAQCIVTAIDCRRNTDIKNNPD 146

Query: 1380 EVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCD 1559
            +     +++    P     AWY+  + GGR++  I A + AK  EELG+GEILL  +D D
Sbjct: 147  KT---VLELEDGTP-----AWYEVVIYGGREATGIDAVQWAKKAEELGSGEILLTSMDRD 198

Query: 1560 GQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPIL 1739
            G   G+D+ + + +S+ + IP+IAS G G  +H  E F +  A AALAA IFH  E  I 
Sbjct: 199  GTCAGYDLPITRKLSEELDIPIIASGGVGNPQHIYEGFSEGKADAALAASIFHFSEYSIW 258

Query: 1740 AVKEHLVDAGVEVRM 1784
             VKE+L +  + VR+
Sbjct: 259  EVKEYLREREIPVRL 273

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>Q97KH8:HIS6_CLOAB Imidazole glycerol phosphate synthase subunit hisF - Clostridium|
            acetobutylicum
          Length = 253

 Score =  176 bits (445), Expect = 4e-43
 Identities = 118/313 (37%), Positives = 164/313 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV   D G +V  KG  +          ++++G PVE+A  Y  +GADE+ 
Sbjct: 2    LTKRIIPCLDV---DMGRVV--KGVNF--------VNLKDVGDPVEIADFYNREGADEIV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   M++V+R  +EKVF+PLTVGGGIRD  D                R
Sbjct: 49   FLDISATNE---GRNTMIDVVRRTAEKVFIPLTVGGGIRDVDD-----------FKNILR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKISI S A+   E             + + ++ +G+Q VVV++D RR         
Sbjct: 95   AGADKISINSAAIRNPEL------------INEAAKKFGSQCVVVAVDARR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E   +   ++GGR    + A E  K  E LGAGEILL  +D DG 
Sbjct: 134  -------------NIETGGFNVFINGGRVDTSLDAIEWVKKCESLGAGEILLTSMDADGT 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D++L   V DAV IPVIAS G G +E F E+F+KT+A AAL A +FH KE  +  V
Sbjct: 181  KNGYDVELTGAVCDAVRIPVIASGGCGRLEDFDEIFKKTSADAALVASLFHYKEYTVGEV 240

Query: 1746 KEHLVDAGVEVRM 1784
            K +L +  ++VR+
Sbjct: 241  KNYLRENSIQVRL 253

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>Q8FNZ9:HIS6_COREF Imidazole glycerol phosphate synthase subunit hisF - Corynebacterium|
            efficiens
          Length = 258

 Score =  175 bits (444), Expect = 5e-43
 Identities = 122/314 (38%), Positives = 173/314 (55%), Gaps = 2/314 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A RVI CLDV   DNG +V  KG  ++         +R+ G PVELA +Y  +GADE++
Sbjct: 3    VAIRVIPCLDV---DNGRVV--KGVNFE--------NLRDAGDPVELAKRYGEEGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+++  +    G   ML+V+R  +E++F+PLTVGGG+R           S+E   +  R
Sbjct: 50   FLDVSASKD---GRGTMLDVVRRTAEQIFIPLTVGGGVR-----------SVEDVDQLLR 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + A+   E             L ++S+ +G Q +V+S+D RRV        
Sbjct: 96   AGADKVSVNTSAIARPEL------------LSELSQRFGAQCIVLSVDARRV-------- 135

Query: 1386 QFRTVKVSSKGPLGE--EYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCD 1559
                       P GE  + + ++ T  GG  S  + A E A   E+LG GEILLN +D D
Sbjct: 136  -----------PAGEAPQPSGFEVTTHGGTRSAGLDAVEWAITGEKLGVGEILLNSMDGD 184

Query: 1560 GQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPIL 1739
            G   GFD++L++ V  AV+IPVIAS GAG  EHF     +  A+A LAA IFH  EV I 
Sbjct: 185  GTKNGFDLELLEKVRAAVSIPVIASGGAGTAEHFPPAV-RAGANAVLAATIFHFGEVTIT 243

Query: 1740 AVKEHLVDAGVEVR 1781
             VK+ +  AG EVR
Sbjct: 244  EVKDAIEKAGFEVR 257

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>Q8PW92:HIS6_METMA Imidazole glycerol phosphate synthase subunit hisF - Methanosarcina|
            mazei (Methanosarcina frisia)
          Length = 273

 Score =  174 bits (441), Expect = 1e-42
 Identities = 120/315 (38%), Positives = 173/315 (54%), Gaps = 2/315 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV  +  G  VV KG ++         +++  G PVELA +Y  DGADE+ 
Sbjct: 2    LTKRIIPCLDVTLDRAGGCVV-KGVEF--------VDLKEAGDPVELAKRYNEDGADELV 52

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   M++V+   +++VF+PLTVGGGI           SS+E   +  R
Sbjct: 53   FLDIT---ASAHGRETMIDVIERTADEVFIPLTVGGGI-----------SSIEAIRQILR 98

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRR-VYVK-SPD 1379
            +GADK+S+ + AV   E             +++ S ++G Q +V +ID +R   VK +PD
Sbjct: 99   AGADKVSVNTSAVKNPEF------------IKESSDIFGAQCIVTAIDCKRNTNVKDNPD 146

Query: 1380 EVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCD 1559
            +     +++    P     AWY+  + GGR +  I A + AK  EELG+GEILL  +D D
Sbjct: 147  KT---ILELEDGTP-----AWYEVVIYGGRKNTGIDAVQWAKRAEELGSGEILLTSMDRD 198

Query: 1560 GQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPIL 1739
            G   G+DI + + +S+ + IP+IAS G G  +H  E F    A AALAA IFH  E  I 
Sbjct: 199  GTCAGYDIPITRKLSEELDIPIIASGGVGNPQHIYEGFSDGKADAALAASIFHFGEYSIQ 258

Query: 1740 AVKEHLVDAGVEVRM 1784
             VKE L +  + VR+
Sbjct: 259  EVKEFLKERKIPVRL 273

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>Q46CC5:HIS6_METBF Imidazole glycerol phosphate synthase subunit hisF - Methanosarcina|
            barkeri (strain Fusaro / DSM 804)
          Length = 273

 Score =  174 bits (441), Expect = 1e-42
 Identities = 114/315 (36%), Positives = 173/315 (54%), Gaps = 2/315 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV  +  G  VV KG ++         +++  G PVELA +Y  +GADE+ 
Sbjct: 2    LTKRIIPCLDVTLDRAGGCVV-KGVEF--------VDLKEAGDPVELAKRYNEEGADELV 52

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   M++V+   +++VF+PLT+GGGI           +S++   +  R
Sbjct: 53   FLDIT---ASAQGRKTMIDVIERTADEVFIPLTIGGGI-----------NSIDAIRQILR 98

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRV--YVKSPD 1379
            +GADK+S+ + AV                 +++ S ++G Q +V +ID RR      +PD
Sbjct: 99   AGADKVSVNTSAV------------KNPDFIKESSDIFGAQCIVTAIDCRRNTDIKNNPD 146

Query: 1380 EVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCD 1559
            +     +++    P     AWY+  + GGR++  I A + A+  EELG+GEILL  +D D
Sbjct: 147  KT---ILELEDGTP-----AWYEVVIYGGREATGIDAVQWARKAEELGSGEILLTSMDRD 198

Query: 1560 GQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPIL 1739
            G   G+D+ + K +S+ + IP+IAS G G  +H  E F    A AALAA IFH +E  I 
Sbjct: 199  GTCAGYDLPITKKLSEELDIPIIASGGVGNPQHIYEGFSIGKADAALAASIFHFREYSIK 258

Query: 1740 AVKEHLVDAGVEVRM 1784
             VKE+L D  + VR+
Sbjct: 259  EVKEYLRDREIPVRL 273

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>Q30PY0:HIS5_THIDN Imidazole glycerol phosphate synthase subunit hisH - Thiomicrospira|
           denitrificans (strain ATCC 33889 / DSM 1351)
          Length = 207

 Score =  172 bits (437), Expect = 4e-42
 Identities = 97/202 (48%), Positives = 126/202 (62%), Gaps = 4/202 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DY  GN+ SV+NA   +G        P+     D+L+ PGVGAFG AM+ L   GM
Sbjct: 2   IAIVDYNMGNLASVQNAFAKIGTQTVIEGDPKKFKEYDKLILPGVGAFGDAMEHLRERGM 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSS---EGLIVPH 548
            +A++E+    +P LGICLG+QLLF+SSEE G   GLG+I G V  FD+S   E L VPH
Sbjct: 62  IEAIKEFAASTKPILGICLGMQLLFESSEEFGEHEGLGLIKGKVVAFDTSKFEETLKVPH 121

Query: 549 IGWNALQITKDTQLLQGADGQH-VYFVHSYHALPSDANKDWISLTCNYGESFISSISMGN 725
           +GWN +  TK+  L +G D +H +YFVHSYHAL  D  KD I  T  YG  F S+++  N
Sbjct: 122 MGWNRM-FTKEHPLFEGLDEEHYLYFVHSYHAL-CDDEKDSIGRTF-YGYEFTSAVAHDN 178

Query: 726 IQAVQFHPEKSGATGLNIFENF 791
           I  +Q HPEKS   GL I ENF
Sbjct: 179 IMGIQPHPEKSHDNGLKILENF 200

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>Q8ZY16:HIS6_PYRAE Imidazole glycerol phosphate synthase subunit hisF - Pyrobaculum|
            aerophilum
          Length = 253

 Score =  172 bits (436), Expect = 5e-42
 Identities = 119/313 (38%), Positives = 170/313 (54%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A R+I CLD+   D    VV KG  +        + +R +G PVE+A +Y  +GADE++
Sbjct: 3    VALRIIPCLDI---DGKAGVVVKGVNF--------QGIREVGDPVEMAVRYEEEGADEIA 51

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
             L+IT   A P G    ++ ++  +E V +P+ VGGG+R           SLE A+  FR
Sbjct: 52   ILDIT---AAPEGRATFIDSVKRVAEAVSIPVLVGGGVR-----------SLEDATTLFR 97

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + AV                 +  ++R +G+Q+ VV+ID +          
Sbjct: 98   AGADKVSVNTAAV------------RNPQLVALLAREFGSQSTVVAIDAK---------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           EY  Y+  V GGR++  + A + AK VEELGAGEILL  ID DG 
Sbjct: 136  ------------WNGEY--YEVYVKGGREATGLDAVKWAKEVEELGAGEILLTSIDRDGT 181

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
            G G+D++LI+ V+D+V IPVIAS GAG VEHF E      A A LAA +FH + + I  V
Sbjct: 182  GLGYDVELIRRVADSVRIPVIASGGAGRVEHFYEA-AAAGADAVLAASLFHFRVLSIAQV 240

Query: 1746 KEHLVDAGVEVRM 1784
            K +L + GVEVR+
Sbjct: 241  KRYLKERGVEVRI 253

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>O53908:HIS6_MYCTU Imidazole glycerol phosphate synthase subunit hisF - Mycobacterium|
            tuberculosis
          Length = 267

 Score =  172 bits (435), Expect = 6e-42
 Identities = 121/315 (38%), Positives = 168/315 (53%)
 Frame = +3

Query: 837  ASKLAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGAD 1016
            A  LA RVI CLDV   D+G +V  KG  ++         +R+ G PVELA+ Y  +GAD
Sbjct: 10   AGGLAVRVIPCLDV---DDGRVV--KGVNFE--------NLRDAGDPVELAAVYDAEGAD 56

Query: 1017 EVSFLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASE 1196
            E++FL++T   A   G   MLEV+R  +E+VF+PLTVGGG+R   D              
Sbjct: 57   ELTFLDVT---ASSSGRATMLEVVRRTAEQVFIPLTVGGGVRTVAD-----------VDS 102

Query: 1197 YFRSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSP 1376
              R+GADK+++ + A+   +             L  ++R +G+Q +V+S+D R V V S 
Sbjct: 103  LLRAGADKVAVNTAAIACPDL------------LADMARQFGSQCIVLSVDARTVPVGS- 149

Query: 1377 DEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDC 1556
                       +  P G     ++ T  GGR    + A + A    +LG GEILLN +D 
Sbjct: 150  -----------APTPSG-----WEVTTHGGRRGTGMDAVQWAARGADLGVGEILLNSMDA 193

Query: 1557 DGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPI 1736
            DG   GFD+ L++ V  AVT+PVIAS GAGAVEHF+       A A LAA +FH +E+ I
Sbjct: 194  DGTKAGFDLALLRAVRAAVTVPVIASGGAGAVEHFAPAV-AAGADAVLAASVFHFRELTI 252

Query: 1737 LAVKEHLVDAGVEVR 1781
              VK  L   G+ VR
Sbjct: 253  GQVKAALAAEGITVR 267

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>Q7VEW8:HIS6_MYCBO Imidazole glycerol phosphate synthase subunit hisF - Mycobacterium|
            bovis
          Length = 267

 Score =  172 bits (435), Expect = 6e-42
 Identities = 121/315 (38%), Positives = 168/315 (53%)
 Frame = +3

Query: 837  ASKLAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGAD 1016
            A  LA RVI CLDV   D+G +V  KG  ++         +R+ G PVELA+ Y  +GAD
Sbjct: 10   AGGLAVRVIPCLDV---DDGRVV--KGVNFE--------NLRDAGDPVELAAVYDAEGAD 56

Query: 1017 EVSFLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASE 1196
            E++FL++T   A   G   MLEV+R  +E+VF+PLTVGGG+R   D              
Sbjct: 57   ELTFLDVT---ASSSGRATMLEVVRRTAEQVFIPLTVGGGVRTVAD-----------VDS 102

Query: 1197 YFRSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSP 1376
              R+GADK+++ + A+   +             L  ++R +G+Q +V+S+D R V V S 
Sbjct: 103  LLRAGADKVAVNTAAIACLDL------------LADMARQFGSQCIVLSVDARTVPVGS- 149

Query: 1377 DEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDC 1556
                       +  P G     ++ T  GGR    + A + A    +LG GEILLN +D 
Sbjct: 150  -----------APTPSG-----WEVTTHGGRRGTGMDAVQWAARGADLGVGEILLNSMDA 193

Query: 1557 DGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPI 1736
            DG   GFD+ L++ V  AVT+PVIAS GAGAVEHF+       A A LAA +FH +E+ I
Sbjct: 194  DGTKAGFDLALLRAVRAAVTVPVIASGGAGAVEHFAPAV-AAGADAVLAASVFHFRELTI 252

Query: 1737 LAVKEHLVDAGVEVR 1781
              VK  L   G+ VR
Sbjct: 253  GQVKAALAAEGITVR 267

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>Q9RPQ4:HIS6_THEET Imidazole glycerol phosphate synthase subunit hisF -|
            Thermoanaerobacter ethanolicus (Clostridium
            thermohydrosulfuricum)
          Length = 254

 Score =  171 bits (433), Expect = 1e-41
 Identities = 118/314 (37%), Positives = 175/314 (55%), Gaps = 1/314 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV    NG +V  KG  +          +R+ G PVE+AS Y   GADE++
Sbjct: 2    VTKRIIPCLDVH---NGRVV--KGVNF--------VNIRDAGDPVEIASYYDKAGADELT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +  L ++ M++V+R  +E+VF+P TVGGGIR           ++E   E  +
Sbjct: 49   FLDITA--SAELRNI-MIDVVRRVAEQVFIPFTVGGGIR-----------TVEDFREILK 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S AV   E             + + +  +G+Q VVV+ID +R         
Sbjct: 95   AGADKVSINSAAVKRPEL------------ISEAASRFGSQCVVVAIDAKR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                          ++ + +   ++GGR +    A E A  VE+LGAGEILL  +DCDG 
Sbjct: 134  -------------RDDNSGWDVYINGGRINTGKDAVEWAVEVEKLGAGEILLTSMDCDGT 180

Query: 1566 GGGFDIDLIKMVSDAVT-IPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILA 1742
              G+DI+L + VS++V  IPVIAS GAG +EHF E   +  A A LAA +FH +E+ I+ 
Sbjct: 181  KKGYDIELTRKVSESVRMIPVIASGGAGTMEHFREALVEGKADAVLAASLFHYREIEIME 240

Query: 1743 VKEHLVDAGVEVRM 1784
            +K++L + G+E+RM
Sbjct: 241  LKKYLKENGIEIRM 254

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>Q8GDQ6:HIS6_HELMO Imidazole glycerol phosphate synthase subunit hisF - Heliobacillus|
            mobilis
          Length = 261

 Score =  171 bits (433), Expect = 1e-41
 Identities = 127/312 (40%), Positives = 163/312 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV         V KG  +          +R+ G PVELA+ Y  +GADE+ 
Sbjct: 2    LAKRIIPCLDVHGGR-----VVKGTNF--------VNLRDAGDPVELAAVYDKEGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   ML+V+R  +E+VF+P TVGGG+R           ++E   E  +
Sbjct: 49   FLDIT---ASSDGRAIMLDVVRRTAEEVFIPFTVGGGLR-----------TVEDIREMLK 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKIS+ + AV       QT    G S+ +     +G+Q +VV+ID RR         
Sbjct: 95   AGADKISLNTSAV-------QTPQLIGDSAWK-----FGSQCIVVAIDARR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                 +   +G L E +  Y     GGR    I   E A+ VEELG GEILL  +D DG 
Sbjct: 134  -----RRDEEGRLLEGWEVY---THGGRKPTGIDVLEWARKVEELGCGEILLTSMDKDGT 185

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L + VS+AV IPVIAS G G +EH  E      A AALAA IFH KE  I   
Sbjct: 186  KDGYDIPLTRAVSEAVKIPVIASGGVGNLEHICEGLTAGKADAALAASIFHYKEYTIRET 245

Query: 1746 KEHLVDAGVEVR 1781
            KE+L   GV VR
Sbjct: 246  KEYLRGKGVHVR 257

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>Q7NNK4:HIS5_GLOVI Imidazole glycerol phosphate synthase subunit hisH - Gloeobacter|
           violaceus
          Length = 226

 Score =  171 bits (433), Expect = 1e-41
 Identities = 96/215 (44%), Positives = 134/215 (62%), Gaps = 4/215 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+DYG GN+ S R  +  +G  +     P  + AAD +V PGVG+F +A+  LN  G+
Sbjct: 7   IALVDYGVGNLHSARKGLEAMGARVTLSGQPLTLSAADGVVLPGVGSFDTAITRLNDRGL 66

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            DA+ + +R  +P LGICLGLQ+LFDSSEE G + GLG++PG VRRF S  GL +PH+GW
Sbjct: 67  GDAIIQLVRAGQPMLGICLGLQVLFDSSEE-GRLPGLGLLPGRVRRFRSEPGLTIPHVGW 125

Query: 558 NALQITK-DTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           N L     D  L +  A G  VYFVHSY+  P+ A +D  +   +  + F +++   N+ 
Sbjct: 126 NQLHFDNVDCPLWRDLAAGGWVYFVHSYYVDPARA-EDRAASAVHGSQHFTAAVCRDNLM 184

Query: 732 AVQFHPEKSGATGLNIFENFL--SPNSSGAKAPAR 830
           AVQFHPEKS  TGL I +NF+  + + S A+  AR
Sbjct: 185 AVQFHPEKSADTGLRILKNFVERAASRSAAEVAAR 219

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>Q7UKJ9:HIS6_RHOBA Imidazole glycerol phosphate synthase subunit hisF - Rhodopirellula|
            baltica
          Length = 262

 Score =  171 bits (432), Expect = 1e-41
 Identities = 118/316 (37%), Positives = 163/316 (51%), Gaps = 3/316 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L+ RVI CLDV         V KG  +          +R+ G PVE+A +Y  +GADE+ 
Sbjct: 2    LSARVIPCLDVHGGR-----VVKGTNF--------VNLRDAGDPVEVARRYEAEGADELV 48

Query: 1026 FLNITGF---RAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASE 1196
            FL+IT     RA       +L+V+R  +E+VF+PLTVGGG+R           ++E    
Sbjct: 49   FLDITASHEERAI------LLDVVRRTAEQVFMPLTVGGGVR-----------TVEDVRA 91

Query: 1197 YFRSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSP 1376
               +G DK+SI S AV            T    + Q +  +G Q +VV+IDP+RV     
Sbjct: 92   LLSAGCDKVSINSSAV------------TNPDFIRQAADRFGRQCIVVNIDPKRVQKD-- 137

Query: 1377 DEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDC 1556
                            GEE+  ++  ++GGR    + A + AK VEELGAGEI+L  +D 
Sbjct: 138  ----------------GEEF--WEVHINGGRKPTGLQAVQWAKRVEELGAGEIVLTSMDA 179

Query: 1557 DGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPI 1736
            DG   G+DI + + VS+AV IPV+AS GAG  +H  E      A A LAA IFH    PI
Sbjct: 180  DGTCDGYDIPITRAVSEAVRIPVVASGGAGNPDHLVEAIRDGKADAVLAASIFHFGTHPI 239

Query: 1737 LAVKEHLVDAGVEVRM 1784
               K+H+ +AG+ VRM
Sbjct: 240  GPTKQHMAEAGIRVRM 255

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>Q465U3:HIS5_METBF Imidazole glycerol phosphate synthase subunit hisH - Methanosarcina|
           barkeri (strain Fusaro / DSM 804)
          Length = 202

 Score =  171 bits (432), Expect = 1e-41
 Identities = 96/202 (47%), Positives = 124/202 (61%), Gaps = 3/202 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + +LDYG GN+RSV+  + H+G +      PE+ILAAD L+ PGVGAF  AM  L+   +
Sbjct: 4   IVILDYGLGNLRSVQKGLEHVGSSPAISGDPEEILAADGLILPGVGAFVDAMKCLD--PI 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              + EY R  +P LGICLG Q+L  SSEE     GL +I G V RF  SE L VPHIGW
Sbjct: 62  KGTIEEYARSGKPMLGICLGQQVLMSSSEEGKLTDGLDLISGKVLRFPKSE-LKVPHIGW 120

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSI--SMGNI 728
           N ++I +D  L +G  D   VYFVHS++    D   +    +CNYG  F +S+  S GN+
Sbjct: 121 NNIKIKQDHPLFEGIPDNSFVYFVHSFYV---DTASENTLASCNYGLDFSASVVNSKGNV 177

Query: 729 QAVQFHPEKSGATGLNIFENFL 794
              QFHPEKSGA GL I +NF+
Sbjct: 178 MGTQFHPEKSGAIGLKILKNFV 199

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>P60714:HIS6_CORDI Imidazole glycerol phosphate synthase subunit hisF - Corynebacterium|
            diphtheriae
          Length = 258

 Score =  169 bits (429), Expect = 3e-41
 Identities = 123/312 (39%), Positives = 171/312 (54%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A RVI CLDV+   NG +V  KG  ++         +++ G PVELA++Y  +GADE++
Sbjct: 3    VAVRVIPCLDVK---NGRVV--KGVNFE--------GLKDAGDPVELAARYDAEGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+++  +    G   MLEV+R  +++VF+PLTVGGG+R           S E   +  R
Sbjct: 50   FLDVSASQD---GRGTMLEVVRRTADQVFIPLTVGGGVR-----------SAEDVDQLLR 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + A+   E             L+++S+ +G Q VV+S+D RRV      + 
Sbjct: 96   AGADKVSVNTSAIARPEL------------LQELSQRFGAQCVVLSVDARRVPEGGKPQ- 142

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                       P G     ++ T  GG  S  I A E A+  E LG GEILLN +D DG 
Sbjct: 143  -----------PSG-----FEVTTHGGTRSAGIDAVEWAQKGEALGVGEILLNSMDGDGT 186

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD++LI+ V  AV+IPVIAS GAG  E F      + A A LAA IFH  EV I  V
Sbjct: 187  KRGFDLELIEKVRHAVSIPVIASGGAGKPEDFPPAI-ASGADAVLAASIFHFGEVTISEV 245

Query: 1746 KEHLVDAGVEVR 1781
            K+ +V AG EVR
Sbjct: 246  KKQVVAAGYEVR 257

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>P60599:HIS5_GEOSL Imidazole glycerol phosphate synthase subunit hisH - Geobacter|
           sulfurreducens
          Length = 209

 Score =  169 bits (429), Expect = 3e-41
 Identities = 92/204 (45%), Positives = 121/204 (59%), Gaps = 6/204 (2%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+RSV+     +GF       P+ +L A+++V PGVGAF   M  L + G 
Sbjct: 4   IAIIDYGMGNLRSVQKGFEKVGFEAVVTADPKVVLEAEKIVLPGVGAFRDCMRNLEQGGF 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEGLIV 542
            + +   IR  RPFLGIC+G+QLL   S E G   GL VIPG V RF     +  E L V
Sbjct: 64  VEPILRVIREGRPFLGICVGMQLLLTDSVEFGLYQGLNVIPGHVLRFPEGMREGGEELKV 123

Query: 543 PHIGWNALQI-TKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISM 719
           PH+GWN L I  +     +  DG +VYFVHSY+ +P D  +  I+ TC YG  F ++I  
Sbjct: 124 PHMGWNQLSIKRRPPAFAEVEDGANVYFVHSYYEMPDD--ESVIAATCTYGVEFCAAIWK 181

Query: 720 GNIQAVQFHPEKSGATGLNIFENF 791
            NI A QFHPEKS A GL+I +NF
Sbjct: 182 DNIVATQFHPEKSQAVGLSILKNF 205

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>Q7ULP3:HIS5_RHOBA Imidazole glycerol phosphate synthase subunit hisH - Rhodopirellula|
           baltica
          Length = 205

 Score =  169 bits (427), Expect = 5e-41
 Identities = 83/198 (41%), Positives = 117/198 (59%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           +T++DY  GN+RSV+ A+   G           I AA+RL+ PGVGAFG A+  + R  +
Sbjct: 2   ITIVDYQMGNLRSVQKAVERSGVEAEITSDASQIAAAERLILPGVGAFGDAIGEIRRRDL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              ++++I   +PFLGICLGLQ+LF+   E G   GLGV+ G V  F+      VPH+GW
Sbjct: 62  EKPIKDFIASGKPFLGICLGLQMLFEQGFEGGTHEGLGVLGGDVVAFELPAEFKVPHMGW 121

Query: 558 NALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQAV 737
           NA+ +      L    G H YFVHSY   P+D +   ++LTC+YG  F +++  GN+ A 
Sbjct: 122 NAVDVKDAGADLGIQSGTHFYFVHSYFVRPADPSV--VALTCDYGGEFCAAVRRGNLMAT 179

Query: 738 QFHPEKSGATGLNIFENF 791
           QFHPEKS   GL + + F
Sbjct: 180 QFHPEKSQGDGLRLMQRF 197

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>Q47QS3:HIS6_THEFY Imidazole glycerol phosphate synthase subunit hisF - Thermobifida|
            fusca (strain YX)
          Length = 256

 Score =  168 bits (426), Expect = 7e-41
 Identities = 123/312 (39%), Positives = 167/312 (53%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LA RVI CLDV   D G +V  KG  +        + +R+ G PVELA +Y  +GADE++
Sbjct: 3    LAVRVIPCLDV---DGGRVV--KGVNF--------QNLRDAGDPVELARRYDAEGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL++T   A         +V+R  +E+VF+PLTVGGG+R           S E      R
Sbjct: 50   FLDVT---ASSSNRETTYDVVRRTAEQVFIPLTVGGGVR-----------STEDVDRLLR 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV   E             + +I++ +G+Q +V+S D RR         
Sbjct: 96   AGADKVSINTAAVRRPEL------------IREIAQEFGSQVLVLSADVRR--------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
               TV  ++  P G     ++ T  GGR    I A E  +  EELGAGEILLN +D DG 
Sbjct: 135  ---TVNGTAT-PSG-----FEITTHGGRQGTGIDAVEWVQQAEELGAGEILLNSMDADGT 185

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD++LI+ V  AV +P+IAS GAGAVEHF+   +   A+A LAA +FH  E+ I  V
Sbjct: 186  KSGFDLELIRAVRKAVNVPLIASGGAGAVEHFAPAVD-AGANAVLAASVFHFGEITISDV 244

Query: 1746 KEHLVDAGVEVR 1781
            K  L   G  VR
Sbjct: 245  KAELRAKGYPVR 256

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>Q5KVC8:HIS5_GEOKA Imidazole glycerol phosphate synthase subunit hisH - Geobacillus|
           kaustophilus
          Length = 211

 Score =  168 bits (426), Expect = 7e-41
 Identities = 87/203 (42%), Positives = 122/203 (60%), Gaps = 4/203 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+ SV  A+  LG         E++  A  L+ PGVG+F  AM +LN TG+
Sbjct: 2   IGIIDYGMGNLYSVSKALERLGCPYVLSGDKEELEQARGLILPGVGSFRDAMHILNETGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF----DSSEGLIVP 545
           A  +R  +    P LGICLG+QLLFD SEENGP  GLG++ G V RF     + E   VP
Sbjct: 62  AAFIRSAVENGTPLLGICLGMQLLFDESEENGPTKGLGLLRGRVVRFPGVTKTGEPYKVP 121

Query: 546 HIGWNALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGN 725
           H+GWN L+  + + LL+G +  HVYFVHSY+ +P D  +D +  +  Y     + +  G 
Sbjct: 122 HMGWNRLRFHRPSPLLRGVEEGHVYFVHSYYVIPGD--EDVVLASSEYDVDVPAVVGRGC 179

Query: 726 IQAVQFHPEKSGATGLNIFENFL 794
           +   QFHPEKSGA G++I  N++
Sbjct: 180 VFGTQFHPEKSGAVGMSILNNYV 202

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>O66943:HIS5_AQUAE Imidazole glycerol phosphate synthase subunit hisH - Aquifex|
           aeolicus
          Length = 207

 Score =  168 bits (426), Expect = 7e-41
 Identities = 96/217 (44%), Positives = 129/217 (59%), Gaps = 2/217 (0%)
 Frame = +3

Query: 204 LLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILA-ADRLVFPGVGAFGSAMDVLNRTGMA 380
           ++DYG GN+RSV  A+  +GF    V +   + + AD LV PGVGAFG AM  L    + 
Sbjct: 5   VIDYGMGNLRSVSKALEAVGFPEVVVSNDYRVASEADVLVLPGVGAFGDAMKNLEELNLV 64

Query: 381 DALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGWN 560
             +R +I   +PFLGICLGLQLLF+ S E+G   GLG++ G V       G+ +PHIGWN
Sbjct: 65  SVIRRHIEKGKPFLGICLGLQLLFEKSYEHGEHRGLGILKGEVILLPL--GVKIPHIGWN 122

Query: 561 ALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQAV 737
            L   K++++L+G  +G  VYFVHSY  +P D  +  +    +YGE F+SSI + N+ A 
Sbjct: 123 QLWFKKESEILEGLKEGDFVYFVHSYRVVPED--ESVVLTKTDYGEYFVSSIELDNVVAF 180

Query: 738 QFHPEKSGATGLNIFENFLSPNSSGAKAPARRKASKL 848
           QFHPEKS   GL + ENF            +RKA KL
Sbjct: 181 QFHPEKSQKKGLKLLENF------------KRKAEKL 205

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>Q81G02:HIS6_BACCR Imidazole glycerol phosphate synthase subunit hisF - Bacillus cereus|
            (strain ATCC 14579 / DSM 31)
          Length = 252

 Score =  167 bits (424), Expect = 1e-40
 Identities = 118/313 (37%), Positives = 162/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV+        V KG  +          ++++G PVE+A  Y   GADE+ 
Sbjct: 2    LAKRIIPCLDVKEGR-----VVKGVNFI--------GLQDVGDPVEIAEAYNEAGADEIV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT       G   +++V+   + KVF+PLTVGGGI           SS++      R
Sbjct: 49   FLDITATHE---GRKTIIDVVEKTAAKVFIPLTVGGGI-----------SSVKDMYNLLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S AV                 +E+ +  +G+Q +VV+ID R+V        
Sbjct: 95   AGADKVSINSAAV------------RNPKLIEEGAEHFGSQCIVVAIDARKV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E  W    V+GGR    + A E AK V +LGAGEILL  +D DG 
Sbjct: 135  --------------AEGKW-NVYVNGGRVDTGMDAIEWAKRVVKLGAGEILLTSMDADGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L + +S +V+IPVIAS G G  +H  EVF+KT   AALAA IFH  E  + +V
Sbjct: 180  KSGYDLRLTEEISKSVSIPVIASGGCGHTDHIIEVFQKTTVDAALAASIFHYGEATVQSV 239

Query: 1746 KEHLVDAGVEVRM 1784
            K  L DA +EVR+
Sbjct: 240  KRKLRDANIEVRL 252

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>Q2RGW0:HIS5_MOOTA Imidazole glycerol phosphate synthase subunit hisH - Moorella|
           thermoacetica (strain ATCC 39073)
          Length = 210

 Score =  167 bits (424), Expect = 1e-40
 Identities = 87/199 (43%), Positives = 123/199 (61%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+ SV+ A+  LG+ +     P +I AA  ++ PGVGAF  AM  L + G+
Sbjct: 4   IAIIDYGMGNLLSVQKALDRLGYPVEVTDDPGEITAAPGVILPGVGAFADAMANLQQKGL 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
             A+RE      P LGICLGLQLLF +SEE G V+GL ++PG V+R  +  G+ VPH+GW
Sbjct: 64  VAAIREVAERGVPLLGICLGLQLLFSTSEEGGQVAGLDLLPGEVKRLPA--GIKVPHMGW 121

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N ++  +   L +G   G   YFVHSY+ +P +  ++ ++ T  YG  F  SI  GN+  
Sbjct: 122 NQVRFPRPGALFRGIPGGTDFYFVHSYYIVPRE--EEVVTGTTEYGLEFAVSIQRGNLFG 179

Query: 735 VQFHPEKSGATGLNIFENF 791
           VQFHPEKS   GL + +NF
Sbjct: 180 VQFHPEKSSRRGLEVLKNF 198

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>Q8TS91:HIS5_METAC Imidazole glycerol phosphate synthase subunit hisH - Methanosarcina|
           acetivorans
          Length = 202

 Score =  167 bits (422), Expect = 2e-40
 Identities = 92/202 (45%), Positives = 123/202 (60%), Gaps = 3/202 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+RSV+  + H+G N     +PE+IL AD ++ PGVGAF  AM  L    +
Sbjct: 4   IVIIDYGLGNLRSVQKGLEHVGANPAISGNPEEILTADGIILPGVGAFIDAMKCL--IPL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              + E+    +P LGICLG Q+L  SSEE     GL +I G V RF  SE L VPH+GW
Sbjct: 62  KGVIAEFAESGKPMLGICLGQQVLMSSSEEGRLTGGLDLIQGRVLRFPKSE-LKVPHMGW 120

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSI--SMGNI 728
           N ++I +D  L +G +DG  VYFVHSY+    D   +    +C YG  F +S+  S GN+
Sbjct: 121 NNIRIKQDHPLFKGISDGSFVYFVHSYYV---DTTAENTLASCEYGLDFSASVVNSKGNV 177

Query: 729 QAVQFHPEKSGATGLNIFENFL 794
              QFHPEKSG TGL I +NF+
Sbjct: 178 MGTQFHPEKSGTTGLKILKNFV 199

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>P61782:HIS51_METMP Imidazole glycerol phosphate synthase subunit hisH 1 -|
           Methanococcus maripaludis
          Length = 203

 Score =  167 bits (422), Expect = 2e-40
 Identities = 94/203 (46%), Positives = 124/203 (61%), Gaps = 4/203 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DY AGN+RS+  A+     NI     PE IL+AD+LV PGVG FG +M  +++   
Sbjct: 2   IAIIDYNAGNLRSIEKALELYTKNIVVTSDPETILSADKLVLPGVGNFGDSMKNISQKTG 61

Query: 378 ADALREYIR---MDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPH 548
             +L E I       PFLGICLG+QLL + SEE     GLGVI G V +F  SE   +PH
Sbjct: 62  DCSLNEIINKCVQKVPFLGICLGMQLLLEKSEECPETPGLGVIKGDVIKFKHSEK--IPH 119

Query: 549 IGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGN 725
           +GWN +   +D  L +G A+ ++ YFVHSYH  PS+  KD IS T NYG  F   ++  N
Sbjct: 120 MGWNTVNQVQDIPLFEGIANNEYFYFVHSYHVNPSE--KDVISGTTNYGYEFPCILNKKN 177

Query: 726 IQAVQFHPEKSGATGLNIFENFL 794
           + A QFHPEKSG  GL + ENF+
Sbjct: 178 VYATQFHPEKSGKNGLKMIENFV 200

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>Q9X7C2:HIS6_MYCLE Imidazole glycerol phosphate synthase subunit hisF - Mycobacterium|
            leprae
          Length = 261

 Score =  166 bits (419), Expect = 4e-40
 Identities = 116/312 (37%), Positives = 161/312 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LA RVI CLDV         V KG  +        K +R+ G  VELA+ Y  +GADE++
Sbjct: 7    LAVRVIPCLDVYCGR-----VVKGVNF--------KNLRDAGDLVELAAAYDAEGADELA 53

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL++T   A   G   MLEV+RC +E+VF+PL VGGG+R   D                R
Sbjct: 54   FLDVT---ASSSGRATMLEVVRCTAEQVFIPLMVGGGVRTVAD-----------VDVLLR 99

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+++ + A+   E             L  ++  +G+Q +V+S+D R V   S    
Sbjct: 100  AGADKVAVNTAAIARPEL------------LADMAGQFGSQCIVLSVDARTVPTGS---- 143

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                    ++ P G     ++ T  GG     I A E A    +LG GEILLN +D DG 
Sbjct: 144  --------ARTPSG-----WEATTHGGYRGTGIDAVEWAARGADLGVGEILLNSMDADGT 190

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ +++ V  AVT+PVIAS GAGA+EHF        A A LAA +FH +E+ I  V
Sbjct: 191  KAGFDLAMLRAVRAAVTVPVIASGGAGAIEHFVPAV-TAGADAVLAASVFHFRELTIGQV 249

Query: 1746 KEHLVDAGVEVR 1781
            K+ +  AG+ VR
Sbjct: 250  KDAMAAAGIAVR 261

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>P62454:HIS6_METMP Imidazole glycerol phosphate synthase subunit hisF - Methanococcus|
            maripaludis
          Length = 272

 Score =  166 bits (419), Expect = 4e-40
 Identities = 108/312 (34%), Positives = 163/312 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLD++        V KG  +         E+R+ G PVEL+  Y   GADE+ 
Sbjct: 2    LTKRIIPCLDIKEGR-----VVKGTNF--------VELRDAGDPVELSKIYNEQGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +F   D+ +++V++  +E+VF+PLTVGGGI+   D             +  R
Sbjct: 49   FLDITA--SFEKRDI-IIDVVKRTAEQVFIPLTVGGGIKTVDD-----------FRKILR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKISI + AV   +             +++ S ++G Q VVV++D +R Y+    + 
Sbjct: 95   AGADKISINTSAVKTPDL------------IKEASEIFGTQCVVVAMDVKRKYITDSQDE 142

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
              +   +     LG    W++  + GGR+   I A E AK VE LGAGEILL  +D DG 
Sbjct: 143  NLKNKNIFET-KLGS--CWFEVYIYGGREGTGIDAIEWAKKVEYLGAGEILLTSMDADGT 199

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L K +S+   +P+IAS G G   H  + F +  A AAL A I H +E  +  +
Sbjct: 200  KDGYDLVLTKAISENTKLPIIASGGCGNANHVVDAFTEGKADAALMASILHYRECTVNDL 259

Query: 1746 KEHLVDAGVEVR 1781
            K+ +    + VR
Sbjct: 260  KKEVEKNNIPVR 271

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>Q5YYP3:HIS6_NOCFA Imidazole glycerol phosphate synthase subunit hisF - Nocardia|
            farcinica
          Length = 257

 Score =  165 bits (418), Expect = 6e-40
 Identities = 119/313 (38%), Positives = 168/313 (53%), Gaps = 1/313 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A RVI CLDV   D G +V  KG  +        + +R+ G PVELA+ Y   GADE++
Sbjct: 3    VAVRVIPCLDV---DAGRVV--KGVNF--------QNLRDAGDPVELAATYDAQGADELT 49

Query: 1026 FLNITGFRAFPLGDL-PMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYF 1202
            FL++T       GD   M++V+   +E++F+PLTVGGG+R           ++E      
Sbjct: 50   FLDVTA----STGDRGTMIDVVTRTAEQIFIPLTVGGGVR-----------TVEDVDRLL 94

Query: 1203 RSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDE 1382
            R+GADK+S+ + A+   E             L ++S  +G+Q +V+S+D R V    PD 
Sbjct: 95   RAGADKVSVNTAAIARPEV------------LREMSERFGSQCIVLSVDARTVPDGQPDT 142

Query: 1383 VQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDG 1562
                        P G     ++ T  GG+    I A E A+   ELG GEILLN +D DG
Sbjct: 143  ------------PSG-----WEVTTHGGKRGTGIDAVEWAERGAELGVGEILLNSMDADG 185

Query: 1563 QGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILA 1742
               GFD+ +I+ V  AV+IPVIAS GAGAVEHF+   +   A A LAA +FH  ++ I  
Sbjct: 186  TKTGFDLPMIRAVRAAVSIPVIASGGAGAVEHFAPAVQ-AGADAVLAASVFHFGDLTIGQ 244

Query: 1743 VKEHLVDAGVEVR 1781
            VK+ L DA + VR
Sbjct: 245  VKDSLRDAHLVVR 257

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>Q92E88:HIS6_LISIN Imidazole glycerol phosphate synthase subunit hisF - Listeria innocua|
          Length = 251

 Score =  165 bits (418), Expect = 6e-40
 Identities = 116/312 (37%), Positives = 158/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV +       V KG  +          + ++G PVE+A  Y   GADE+ 
Sbjct: 2    LTKRIIPCLDVTAGR-----VVKGVNF--------VSLTDVGDPVEIAKAYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT           M++V+   +E+VF+PLTVGGGI    D             E  +
Sbjct: 49   FLDITATVELRQ---TMIDVVERTAEQVFIPLTVGGGINSVND-----------MKELLQ 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKIS+ S A+   E             +++ +  +GNQ +VV+ID +          
Sbjct: 95   AGADKISLNSAAIKRPEL------------IQEGANKFGNQCIVVAIDAK---------- 132

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                              W+  T  GGRD   + A E AK   +LGAGEILL  +D DG 
Sbjct: 133  -------------WNGSNWHVFT-RGGRDDTGLDAIEWAKKATQLGAGEILLTSMDGDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L K +S+AV++PVIAS G G   H  EVFE+TNA+AALAA IFH  E+ I  V
Sbjct: 179  KNGYDIPLTKAISEAVSVPVIASGGCGNASHMVEVFEQTNATAALAASIFHYGELSIKNV 238

Query: 1746 KEHLVDAGVEVR 1781
            K  L++ GV +R
Sbjct: 239  KTTLLEKGVNIR 250

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>Q8R883:HIS5_THETN Imidazole glycerol phosphate synthase subunit hisH -|
           Thermoanaerobacter tengcongensis
          Length = 203

 Score =  165 bits (418), Expect = 6e-40
 Identities = 86/199 (43%), Positives = 125/199 (62%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+RSV  A++++G++ +     ++I   + L+ PGVGAF  A+ VL +TGM
Sbjct: 2   IGIIDYGMGNLRSVEKALKYVGYDAKITSDAKEIKNFEALILPGVGAFPDAIRVLIKTGM 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
           A+ ++ +I   +PFLGICLG+QLLF+ S E G   GL +  G V      +G  +PH+GW
Sbjct: 62  AEEIKIHIEKGKPFLGICLGMQLLFEKSFEGGKTEGLKIFKGNV--VGLPKGNKIPHVGW 119

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N+L I KDT  L+G  +G +VYFVHSY+   +   KD+      YG    + I   N+ +
Sbjct: 120 NSLTIKKDTPFLKGIKNGDYVYFVHSYYV--NGNEKDFEYAVTEYGIEIPAVIIKDNVFS 177

Query: 735 VQFHPEKSGATGLNIFENF 791
            QFHPEKSG TGL I +NF
Sbjct: 178 CQFHPEKSGETGLKILKNF 196

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>Q63DW8:HIS6_BACCZ Imidazole glycerol phosphate synthase subunit hisF - Bacillus cereus|
            (strain ZK / E33L)
          Length = 252

 Score =  165 bits (417), Expect = 7e-40
 Identities = 118/313 (37%), Positives = 162/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV+        V KG  +          ++++G PVE+A+ Y   GADE+ 
Sbjct: 2    LAKRIIPCLDVKEGR-----VVKGVNFI--------GLQDVGDPVEIAALYNDAGADEIV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT       G   +++V+   + KVF+PLTVGGGI           SS++      R
Sbjct: 49   FLDITATHE---GRKTIIDVVEKTASKVFIPLTVGGGI-----------SSVKDMYNLLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S AV                 +E+ ++ +G+Q +VV+ID R+V        
Sbjct: 95   AGADKVSINSAAV------------RNPKLIEEGAQHFGSQCIVVAIDARKV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E  W    V+GGR    + A E AK V  LGAGEILL  +D DG 
Sbjct: 135  --------------AEGKW-NVYVNGGRVDTGMDAIEWAKCVVMLGAGEILLTSMDADGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L + +S +V++PVIAS G G  +H  EVF+KT   AALAA IFH  E  I  V
Sbjct: 180  KNGYDLRLTEEISKSVSVPVIASGGCGHADHIIEVFQKTTVDAALAASIFHYGEATIGGV 239

Query: 1746 KEHLVDAGVEVRM 1784
            K  L +A VEVR+
Sbjct: 240  KRKLRNANVEVRL 252

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>Q3ZY50:HIS5_DEHSC Imidazole glycerol phosphate synthase subunit hisH -|
           Dehalococcoides sp. (strain CBDB1)
          Length = 205

 Score =  165 bits (417), Expect = 7e-40
 Identities = 84/199 (42%), Positives = 123/199 (61%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+DYG GN++SV NAI  LG+       P++IL+A  ++ PGVGA    +  L   G+
Sbjct: 2   IALVDYGGGNLKSVANAIHALGYEFTLTSDPKEILSAQAVILPGVGAAADTVAGLRAKGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            +A++E ++ D P L IC+G+Q+LFDS+EE G    LG++ G V+R    +G+ +P +GW
Sbjct: 62  DEAIKELVKRDIPLLAICVGMQVLFDSTEEGGQTKCLGILAGEVKRL--PDGVKIPQMGW 119

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L+      L +G  DG   YFVHSY+A P+D N   I  T +YG  F S +    + A
Sbjct: 120 NQLKQRVSHPLFEGIPDGTDFYFVHSYYASPADRN--IIGATTDYGVDFCSLVINKRLIA 177

Query: 735 VQFHPEKSGATGLNIFENF 791
            QFHPEKSG+ GL +++NF
Sbjct: 178 TQFHPEKSGSYGLKLYQNF 196

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>P60715:HIS6_GEOSL Imidazole glycerol phosphate synthase subunit hisF - Geobacter|
            sulfurreducens
          Length = 253

 Score =  164 bits (416), Expect = 1e-39
 Identities = 119/313 (38%), Positives = 161/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV+        V KG Q+         E+R+ G PVE+A  Y   GADE++
Sbjct: 2    LTKRIIPCLDVKGGR-----VVKGVQF--------LELRDAGDPVEIAELYDRQGADELT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       +++V+R  +E+VF+PLTVGGG+R   D                 
Sbjct: 49   FLDIT---ASSDERSIIIDVVRRTAERVFMPLTVGGGVRTVDD-----------IRNLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV   E             + + +  +G+Q  VV+ID R+V    P E 
Sbjct: 95   AGADKVSINTAAVHRPEF------------VREAAERFGSQCTVVAIDARQV----PGEN 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
            +                  ++    GGR+   I A E A+ +EE GAGEILL  +D DG 
Sbjct: 139  R------------------WEVYTHGGRNPTGIDAVEWARRMEEYGAGEILLTSMDRDGT 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L + + DAV+IPVIAS G G +EH  + F K  ASA LAA IFH KE  I   
Sbjct: 181  KDGYDIPLTRAIVDAVSIPVIASGGVGNLEHLYDGFVKAGASACLAASIFHYKEYTIGEA 240

Query: 1746 KEHLVDAGVEVRM 1784
            KE+L   GV VR+
Sbjct: 241  KEYLRQRGVPVRL 253

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>Q92E86:HIS5_LISIN Imidazole glycerol phosphate synthase subunit hisH - Listeria|
           innocua
          Length = 208

 Score =  164 bits (416), Expect = 1e-39
 Identities = 82/198 (41%), Positives = 117/198 (59%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DY  GN +S+  A+  +G   +   +  +IL AD ++ PGVGAF  AM  L R G+
Sbjct: 2   IVIIDYDTGNTKSISKALDFIGLQNKISSNHAEILQADGVILPGVGAFPEAMQELGRRGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              L+E     +P LG+CLG+QLL +SS+E+    GLG+IPG V +     G  VPH+GW
Sbjct: 62  DVTLKEMAESGKPMLGVCLGMQLLLESSDEHLFTKGLGLIPGHVEKLPDEPGFAVPHMGW 121

Query: 558 NALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQAV 737
           N L+I + T L +   G++VY+VHSY+A   +   ++I  T  Y     S I+ GNI   
Sbjct: 122 NQLEIKRSTPLTKKLGGEYVYYVHSYYA---NCPNEYIIATSGYSVEVPSMINKGNIYGA 178

Query: 738 QFHPEKSGATGLNIFENF 791
           QFHPEKSG  GL I + F
Sbjct: 179 QFHPEKSGQIGLEILKGF 196

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>Q39YP2:HIS6_GEOMG Imidazole glycerol phosphate synthase subunit hisF - Geobacter|
            metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
          Length = 253

 Score =  164 bits (415), Expect = 1e-39
 Identities = 119/313 (38%), Positives = 161/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV+        V KG Q+         E+R+ G PVE+A  Y   GADE++
Sbjct: 2    LTKRIIPCLDVKGGR-----VVKGVQF--------LELRDAGDPVEIAEAYDRQGADELT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       +++V+R  +E+VF+PLTVGGG+R   D                 
Sbjct: 49   FLDIT---ASSDERNIIIDVVRRTAERVFMPLTVGGGVRIVDD-----------IRNLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV   E             + + +  +G+Q  VV+ID R+V    P E 
Sbjct: 95   AGADKVSINTAAVHRPEF------------VREAAERFGSQCTVVAIDARQV----PGEN 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
            +                  ++    GGR+   I A E A+ +EE GAGEILL  +D DG 
Sbjct: 139  R------------------WEVYTHGGRNPTGIDAVEWARRMEEYGAGEILLTSMDRDGT 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L + + DAV+IPVIAS G G +EH  + F K  ASA LAA IFH KE  I   
Sbjct: 181  KDGYDISLTRAIVDAVSIPVIASGGVGNLEHLHDGFVKAGASACLAASIFHYKEYTIGEA 240

Query: 1746 KEHLVDAGVEVRM 1784
            KE+L   GV VR+
Sbjct: 241  KEYLRGRGVPVRL 253

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>Q39YP4:HIS5_GEOMG Imidazole glycerol phosphate synthase subunit hisH - Geobacter|
           metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
          Length = 210

 Score =  164 bits (414), Expect = 2e-39
 Identities = 89/205 (43%), Positives = 122/205 (59%), Gaps = 6/205 (2%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTG 374
           T+ ++DYG GN+RSV+     +GF       P+ +L A+++V PGVGAF   M  L + G
Sbjct: 3   TIAIIDYGMGNLRSVQKGFEKVGFEAVVTADPKVVLEAEKVVLPGVGAFRDCMRNLEQGG 62

Query: 375 MADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEGLI 539
             + +   I+  RPFLGIC+G+QLLF  S E G   GL VIPG V RF     +  E L 
Sbjct: 63  FVEPILTVIQDGRPFLGICVGMQLLFTDSVEFGLYQGLNVIPGHVLRFPEGMRERGEDLK 122

Query: 540 VPHIGWNALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSIS 716
           VPH+GWN L I +         DG +VYFVHS++A P +  +  ++ T +YG  F +++ 
Sbjct: 123 VPHMGWNQLSIKRRPSAFSDVEDGANVYFVHSFYAKPDE--EGVVAATSSYGIDFCAAVW 180

Query: 717 MGNIQAVQFHPEKSGATGLNIFENF 791
             NI A QFHPEKS A GL+I +NF
Sbjct: 181 KDNIVATQFHPEKSQAVGLSILKNF 205

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>Q970Z0:HIS6_SULTO Imidazole glycerol phosphate synthase subunit hisF - Sulfolobus|
            tokodaii
          Length = 249

 Score =  163 bits (412), Expect = 3e-39
 Identities = 123/312 (39%), Positives = 171/312 (54%)
 Frame = +3

Query: 849  AKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVSF 1028
            AKR+IACLDV+   NG +V  KG  +          +++ G PVELAS+Y  +GADE+ F
Sbjct: 3    AKRIIACLDVK---NGRVV--KGVNF--------LNLKDKGDPVELASRYEEEGADEIVF 49

Query: 1029 LNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRS 1208
            L+IT   A   G   +LEV++  +  + +PLTVGGGIR           ++E  S    +
Sbjct: 50   LDIT---ATIEGRKALLEVVKNTASVLSIPLTVGGGIR-----------TIEDVSRILGN 95

Query: 1209 GADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQ 1388
            GADK+SI + AV              K  + + S  +G QA+VV+ID +RV         
Sbjct: 96   GADKVSINTAAV------------ENKKIITEASEQFGAQAIVVAIDVKRV--------- 134

Query: 1389 FRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQG 1568
                            ++   T SG  ++  I A + AK VE+LGAGEILL  ID DG  
Sbjct: 135  --------------NNSFIVFTRSGTYNTG-IDAIQWAKEVEKLGAGEILLTSIDKDGTR 179

Query: 1569 GGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVK 1748
             G+DI+L K V+++V IPVIAS GAG +EHF EV +   A AALAAG+FH   + I  +K
Sbjct: 180  EGYDIELTKEVNNSVNIPVIASGGAGKMEHFYEVLKV--ADAALAAGVFHDGVIKIPELK 237

Query: 1749 EHLVDAGVEVRM 1784
              L++ G+EVR+
Sbjct: 238  RFLLEKGIEVRV 249

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>O33774:HIS6_SULSO Imidazole glycerol phosphate synthase subunit hisF - Sulfolobus|
            solfataricus
          Length = 251

 Score =  163 bits (412), Expect = 3e-39
 Identities = 124/311 (39%), Positives = 164/311 (52%)
 Frame = +3

Query: 852  KRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVSFL 1031
            KR+IACLDV+  +     V KG  +          ++  G PV LAS Y  +GADE+ FL
Sbjct: 4    KRIIACLDVKDGN-----VVKGVNF--------LNLQLKGDPVSLASLYEEEGADEIVFL 50

Query: 1032 NITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRSG 1211
            +IT   A       +  V++  +  + +PLTVGGGIR   D            S   RSG
Sbjct: 51   DIT---ATIEARKALYNVIKDTASVLSIPLTVGGGIRTPDD-----------VSMALRSG 96

Query: 1212 ADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQF 1391
            ADK+SI + AV +++          K S E+    +G+QAVVV+ID +            
Sbjct: 97   ADKVSINTAAVESSQIV--------KKSAEE----FGSQAVVVAIDVK------------ 132

Query: 1392 RTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQGG 1571
               KVS          W   T SG  ++R + A + AK VEELGAGEILL  ID DG   
Sbjct: 133  ---KVSGN--------WIVFTKSGTYNTR-LDAIKWAKKVEELGAGEILLTSIDRDGTRL 180

Query: 1572 GFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVKE 1751
            G+D++L + + D+V IPVIAS GAG +EHF EVF    A AALAAGIFH   + I  +K 
Sbjct: 181  GYDLELTRKIVDSVNIPVIASGGAGKMEHFYEVFSLAKADAALAAGIFHDGIIKIKDLKS 240

Query: 1752 HLVDAGVEVRM 1784
            +L   G+EVRM
Sbjct: 241  YLSQKGIEVRM 251

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>Q8KF56:HIS5_CHLTE Imidazole glycerol phosphate synthase subunit hisH - Chlorobium|
           tepidum
          Length = 201

 Score =  163 bits (412), Expect = 3e-39
 Identities = 90/199 (45%), Positives = 117/199 (58%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V + DYGAGN+RSV  A  +LG          ++   D+++ PGVGAFG AM+ LNR G 
Sbjct: 2   VFIADYGAGNLRSVHKAFDYLGIEAVVSDKASEMSRYDKVLIPGVGAFGPAMEALNRQGF 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            +A+RE+I   R  LGICLG+QL    SEE G   GL ++PG V RF SS   I P IGW
Sbjct: 62  DEAIREHIDKGRSVLGICLGMQLFLSESEEMGAYKGLDIVPGKVLRFTSSTDKI-PQIGW 120

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N++   KD+ L +   D  + YFVHSY+  P D  +   + T   G+ F S+I    I A
Sbjct: 121 NSVDYCKDSVLFRNVPDQSYFYFVHSYYCAP-DEPESVAATTFFAGKKFCSAIEKNGIFA 179

Query: 735 VQFHPEKSGATGLNIFENF 791
           VQFHPEKS   GL + +NF
Sbjct: 180 VQFHPEKSSEAGLQVLKNF 198

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>P58800:HIS6_PYRFU Imidazole glycerol phosphate synthase subunit hisF - Pyrococcus|
            furiosus
          Length = 251

 Score =  162 bits (409), Expect = 6e-39
 Identities = 120/313 (38%), Positives = 164/313 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LA+R+IA LD++     D  V KG ++        K +R+ G P+ELA +Y  +G DE+ 
Sbjct: 2    LARRIIAALDIK-----DGRVVKGIKF--------KNIRDAGDPIELAKRYESEGIDEIV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   ++    + +L+++   +E+++VP TVGGGIR           ++E A E  R
Sbjct: 49   FLDITA--SYEKRKI-LLDLVERVAEEIYVPFTVGGGIR-----------TVEEAREIIR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADKI I + AV               S +++I+ + G+  +VV+ID +          
Sbjct: 95   RGADKIFINTAAV------------ENPSLIKEIADLIGSANLVVAIDAKW--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                      G   E Y        GGR  R + A E AK VEELGAGEILL  +D DG 
Sbjct: 134  ---------NGKFWEVYT------HGGRKPRGMDAVEWAKRVEELGAGEILLTSMDTDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI L K V DAV IPVIAS GAG  EHF EVF +  + AALAA IFH  E  +  +
Sbjct: 179  KQGFDIPLTKAVVDAVNIPVIASGGAGKPEHFLEVF-RIGSDAALAASIFHYGEYTVREL 237

Query: 1746 KEHLVDAGVEVRM 1784
            K  L   G+ VR+
Sbjct: 238  KMFLAKNGIPVRL 250

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>Q3A137:HIS6_PELCD Imidazole glycerol phosphate synthase subunit hisF - Pelobacter|
            carbinolicus (strain DSM 2380 / Gra Bd 1)
          Length = 255

 Score =  162 bits (409), Expect = 6e-39
 Identities = 117/313 (37%), Positives = 160/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV+     D  V KG Q+         E+R+ G PVE A  Y   GADE++
Sbjct: 2    LTKRIIPCLDVK-----DGRVVKGVQF--------LELRDAGDPVEAAEAYDAQGADELT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       +L+V+   +E+VF+PLTVGGGIR           ++E       
Sbjct: 49   FLDIT---ASSDKRNIILDVVSRTAERVFMPLTVGGGIR-----------TIEDIRNLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI ++AV   E             +++ +  +G+Q +VV+ID RRV    P   
Sbjct: 95   AGADKVSINTEAVNNPEF------------VKEAAERFGSQCIVVAIDARRVADSDPQR- 141

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               ++  + GGR    I A E A  +E  GAGEILL  +D DG 
Sbjct: 142  -------------------WEVYIHGGRTPTGIDAMEWAMRMEAYGAGEILLTSMDKDGT 182

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L + +SD V+IPVIAS G G +EH  +   +  ASAALAA IFH +E  I   
Sbjct: 183  KDGYDIPLTRTISDLVSIPVIASGGVGNLEHIHQGLTEGGASAALAASIFHFREYTIHEC 242

Query: 1746 KEHLVDAGVEVRM 1784
            KE+L   GV  R+
Sbjct: 243  KEYLQKRGVPARL 255

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>P62453:HIS6_THET2 Imidazole glycerol phosphate synthase subunit hisF - Thermus|
            thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
          Length = 252

 Score =  161 bits (408), Expect = 8e-39
 Identities = 121/316 (38%), Positives = 165/316 (52%), Gaps = 3/316 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR++ CLDV +       V KG  +          +R+ G PVE A  Y   GADE+ 
Sbjct: 3    LAKRIVPCLDVHAGR-----VVKGVNF--------VNLRDAGDPVEAARAYDEAGADELV 49

Query: 1026 FLNITGF---RAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASE 1196
            FL+I+     RA       +L+V+   +E+VF+PLTVGGG+R           SLE A +
Sbjct: 50   FLDISATHEERAI------LLDVVARVAERVFIPLTVGGGVR-----------SLEDARK 92

Query: 1197 YFRSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSP 1376
               SGADK+S+ S AV   E             + +++  +G QAVV++ID R       
Sbjct: 93   LLLSGADKVSVNSAAVRRPEL------------IRELADHFGAQAVVLAIDARW------ 134

Query: 1377 DEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDC 1556
                        +G   E Y      V+GGR    + A E A    ELGAGEILL  +D 
Sbjct: 135  ------------RGDFPEVY------VAGGRVPTGLHAVEWAVKGVELGAGEILLTSMDR 176

Query: 1557 DGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPI 1736
            DG   G+D+ L +MV++AV +PVIAS GAG +EHF E F+   A AALAA +FH  E+PI
Sbjct: 177  DGTKEGYDLRLTRMVAEAVGVPVIASGGAGRMEHFLEAFQ-AGAEAALAASVFHFGEIPI 235

Query: 1737 LAVKEHLVDAGVEVRM 1784
              +K +L + GV VR+
Sbjct: 236  PELKRYLAEKGVHVRL 251

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>Q6HLE3:HIS6_BACHK Imidazole glycerol phosphate synthase subunit hisF - Bacillus|
            thuringiensis subsp. konkukian
          Length = 252

 Score =  161 bits (408), Expect = 8e-39
 Identities = 118/313 (37%), Positives = 161/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV+        V KG  +          ++++G PVE+A+ Y   GADE+ 
Sbjct: 2    LAKRIIPCLDVKEGR-----VVKGVNFI--------GLQDVGDPVEIAALYNDAGADEIV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT       G   +++V+   + KVF+PLTVGGGI           SS++      R
Sbjct: 49   FLDITATHE---GRKTIIDVVEKTASKVFIPLTVGGGI-----------SSVKDMYNLLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S AV                 +E+ ++ +G+Q +VV+ID R+V        
Sbjct: 95   AGADKVSINSAAV------------RNPKLIEEGAQHFGSQCIVVAIDARKV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E  W    V+GGR    + A   AK V  LGAGEILL  +D DG 
Sbjct: 135  --------------AEGKW-NVYVNGGRVDTGMDAIGWAKRVVMLGAGEILLTSMDADGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L + +S +V+IPVIAS G G  +H  EVF+KT   AALAA IFH  E  I  V
Sbjct: 180  KNGYDLRLTEEISKSVSIPVIASGGCGHADHIIEVFQKTTVDAALAASIFHYGEATIGDV 239

Query: 1746 KEHLVDAGVEVRM 1784
            K  L +A VEVR+
Sbjct: 240  KRKLRNANVEVRL 252

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>Q81T58:HIS6_BACAN Imidazole glycerol phosphate synthase subunit hisF - Bacillus|
            anthracis
          Length = 252

 Score =  161 bits (408), Expect = 8e-39
 Identities = 118/313 (37%), Positives = 161/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV+        V KG  +          ++++G PVE+A+ Y   GADE+ 
Sbjct: 2    LAKRIIPCLDVKEGR-----VVKGVNFI--------GLQDVGDPVEIAALYNDAGADEIV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT       G   +++V+   + KVF+PLTVGGGI           SS++      R
Sbjct: 49   FLDITATHE---GRKTIIDVVEKTASKVFIPLTVGGGI-----------SSVKDMYNLLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S AV                 +E+ ++ +G+Q +VV+ID R+V        
Sbjct: 95   AGADKVSINSAAV------------RNPKLIEEGAQHFGSQCIVVAIDARKV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E  W    V+GGR    + A   AK V  LGAGEILL  +D DG 
Sbjct: 135  --------------AEGKW-NVYVNGGRVDTGMDAIGWAKRVVMLGAGEILLTSMDADGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L + +S +V+IPVIAS G G  +H  EVF+KT   AALAA IFH  E  I  V
Sbjct: 180  KNGYDLRLTEEISKSVSIPVIASGGCGHADHIIEVFQKTTVDAALAASIFHYGEATIGDV 239

Query: 1746 KEHLVDAGVEVRM 1784
            K  L +A VEVR+
Sbjct: 240  KRKLRNANVEVRL 252

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>Q3B286:HIS5_PELLD Imidazole glycerol phosphate synthase subunit hisH - Pelodictyon|
           luteolum (strain DSM 273) (Chlorobium luteolum (strain
           DSM 273))
          Length = 201

 Score =  161 bits (408), Expect = 8e-39
 Identities = 89/199 (44%), Positives = 118/199 (59%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V + DYGAGN+RSV+ A  +LG        P  +    ++V PGVGAFG A++ L+R G 
Sbjct: 2   VFIADYGAGNLRSVQKAFDYLGIPATVSSDPAKMAGCRKVVLPGVGAFGQAIEALDRLGF 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            DAL E++       GICLG+QL+   SEE G   GLG+IPG VR F S    I P IGW
Sbjct: 62  TDALSEHVDKGGHLFGICLGMQLMLSDSEEMGSHRGLGLIPGSVRHFQSDSDKI-PQIGW 120

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N++ + +++ L +G AD    YFVHSY+  P +A+    S T   G++F S+I    I A
Sbjct: 121 NSIDLKQESVLFRGIADHSFFYFVHSYYCDPLEAS-SIASTTWFAGKNFCSAIEKNGIFA 179

Query: 735 VQFHPEKSGATGLNIFENF 791
           VQFHPEKS   GL +  NF
Sbjct: 180 VQFHPEKSSEAGLQVLRNF 198

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>Q8PVD5:HIS5_METMA Imidazole glycerol phosphate synthase subunit hisH - Methanosarcina|
           mazei (Methanosarcina frisia)
          Length = 202

 Score =  161 bits (408), Expect = 8e-39
 Identities = 90/202 (44%), Positives = 121/202 (59%), Gaps = 3/202 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+RSV+  + H G +     +PE+ILAAD ++ PGVGAF  AM  L    +
Sbjct: 4   IVIIDYGLGNLRSVQKGLEHAGASPAISGNPEEILAADGIILPGVGAFIDAMKCL--VPL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              + E+    +P LGICLG Q+L  SSEE     GL +I G V RF  SE L VP +GW
Sbjct: 62  KKTIAEFAESGKPMLGICLGQQVLMSSSEEGRLTDGLDLIQGRVLRFPKSE-LKVPQMGW 120

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSI--SMGNI 728
           N +++ +D  L +G  DG  VYFVHSY+    D   +    +C YG  + +S+  S GN+
Sbjct: 121 NNIRVKQDHPLFKGIPDGSFVYFVHSYYV---DTAAENTLASCEYGLEYAASVVNSKGNV 177

Query: 729 QAVQFHPEKSGATGLNIFENFL 794
              QFHPEKSGATGL I  NF+
Sbjct: 178 MGTQFHPEKSGATGLKILRNFV 199

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>Q8Y9G5:HIS6_LISMO Imidazole glycerol phosphate synthase subunit hisF - Listeria|
            monocytogenes
          Length = 251

 Score =  161 bits (407), Expect = 1e-38
 Identities = 116/312 (37%), Positives = 158/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV +       V KG  +          + ++G PVE+A  Y   GADE+ 
Sbjct: 2    LTKRIIPCLDVTAGR-----VVKGVNF--------VSLTDVGDPVEIAKAYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT           M++V+   +E+VF+PLTVGGGI           SS+    E  +
Sbjct: 49   FLDITATVELRQ---TMIDVVERTAEQVFIPLTVGGGI-----------SSVSDMKELLQ 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKIS+ S A+   E   +   K            +GNQ +VV+ID +          
Sbjct: 95   AGADKISLNSAAIKRPELIQEGAAK------------FGNQCIVVAIDAKWN-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         G  ++ +     GGR+   + A E AK   +LGAGEILL  +D DG 
Sbjct: 135  -------------GTNWSVF---TRGGRNDTGLDAIEWAKKAVQLGAGEILLTSMDGDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L K +S+AV++PVIAS G G   H  EVFEKT A+AALAA IFH  E+ I  V
Sbjct: 179  KNGYDIPLTKAISEAVSVPVIASGGCGNAAHMVEVFEKTKATAALAASIFHYGELSIKNV 238

Query: 1746 KEHLVDAGVEVR 1781
            K  L++ GV +R
Sbjct: 239  KTTLLEKGVNIR 250

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>Q722Y7:HIS6_LISMF Imidazole glycerol phosphate synthase subunit hisF - Listeria|
            monocytogenes serotype 4b (strain F2365)
          Length = 251

 Score =  160 bits (406), Expect = 1e-38
 Identities = 116/312 (37%), Positives = 158/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV +       V KG  +          + ++G PVE+A  Y   GADE+ 
Sbjct: 2    LTKRIIPCLDVTAGR-----VVKGVNF--------VSLTDVGDPVEIAKAYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT           M++V+   +E+VF+PLTVGGGI           SS+    E  +
Sbjct: 49   FLDITATVELRQ---TMIDVVERTAEQVFIPLTVGGGI-----------SSVSDMKELLQ 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKIS+ S A+   E   +   K            +GNQ +VV+ID +          
Sbjct: 95   AGADKISLNSAAIKRPELIQEGAAK------------FGNQCIVVAIDAKWN-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         G  ++ +     GGR+   + A E AK   +LGAGEILL  +D DG 
Sbjct: 135  -------------GTNWSVF---TRGGRNDTGLDAIEWAKKAVQLGAGEILLTSMDGDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L K +S AV++PVIAS G G   H +EVFEKT A+AALAA IFH  E+ I  V
Sbjct: 179  KNGYDIPLTKAISAAVSVPVIASGGCGNAAHMAEVFEKTKATAALAASIFHYGELSIKNV 238

Query: 1746 KEHLVDAGVEVR 1781
            K  L++ GV +R
Sbjct: 239  KTTLLEKGVNIR 250

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>P62449:HIS6_BACC1 Imidazole glycerol phosphate synthase subunit hisF - Bacillus cereus|
            (strain ATCC 10987)
          Length = 252

 Score =  160 bits (406), Expect = 1e-38
 Identities = 119/313 (38%), Positives = 161/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKRVI CLDV+        V KG  +          ++++G PVE+A+ Y   GADE+ 
Sbjct: 2    LAKRVIPCLDVKEGR-----VVKGVNFI--------GLQDVGDPVEIAALYNDAGADEIV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT       G   +++V+   + KVF+PLTVGGGI +  D     Y+ L       R
Sbjct: 49   FLDITATHE---GRKTIVDVVEKTASKVFIPLTVGGGISNVKD----MYNLL-------R 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S AV                 + + +  +G+Q +VV+ID R+V        
Sbjct: 95   AGADKVSINSAAV------------RNPKLIGEGAEHFGSQCIVVAIDARKV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E  W    V+GGR    + A   AK V ELGAGEILL  +D DG 
Sbjct: 135  --------------AEDKW-NVYVNGGRVDTGMDAIRWAKRVTELGAGEILLTSMDADGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L + +S +V++PVIAS G G  +H  EVF+KT   AALAA IFH  E  I  V
Sbjct: 180  KNGYDLRLTEEISKSVSVPVIASGGCGHADHIIEVFQKTAVDAALAASIFHYGEATIGDV 239

Query: 1746 KEHLVDAGVEVRM 1784
            K  L +A VEVR+
Sbjct: 240  KRKLRNANVEVRL 252

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>Q4KJS4:HIS6_PSEF5 Imidazole glycerol phosphate synthase subunit hisF - Pseudomonas|
            fluorescens (strain Pf-5 / ATCC BAA-477)
          Length = 256

 Score =  160 bits (405), Expect = 2e-38
 Identities = 116/312 (37%), Positives = 165/312 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG +++         +R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDV---DNGRVV--KGVKFE--------NIRDAGDPVEIARRYDEQGADEIT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D  +  V R AS+ VF+PLTVGGG+R   D                 
Sbjct: 50   FLDITA--SVDGRDTTLHTVERMASQ-VFIPLTVGGGVRTVQD-----------IRNLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AVF  E             + + ++ +G+Q +VV+ID ++V        
Sbjct: 96   AGADKVSINTAAVFNPEF------------VGEAAQHFGSQCIVVAIDAKKV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                      GP GE   W +    GGR    + A E AK +E LGAGEILL  +D DG 
Sbjct: 136  ---------SGP-GEAPRW-EIFTHGGRKPTGLDAVEWAKKMEGLGAGEILLTSMDQDGM 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ + + +SDA+ IPVIAS G G ++H ++   + +ASA LAA IFH  E  +   
Sbjct: 185  KNGFDLGVTRAISDALGIPVIASGGVGNLQHLADGIIEGHASAVLAASIFHFGEYTVPEA 244

Query: 1746 KEHLVDAGVEVR 1781
            K ++   G+ VR
Sbjct: 245  KAYMAQRGIVVR 256

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>Q57929:HIS5_METJA Imidazole glycerol phosphate synthase subunit hisH - Methanococcus|
           jannaschii
          Length = 196

 Score =  160 bits (405), Expect = 2e-38
 Identities = 87/200 (43%), Positives = 125/200 (62%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DY AGN+RS++ A+  L   +    + E++LA D+++ PGVG FGSAM+  N   +
Sbjct: 2   IGIIDYNAGNLRSIQKAVE-LYDKVIITNNSEELLACDKIILPGVGNFGSAME--NLAPL 58

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + + + +    PFLGICLG+Q+LF+ SEE   + GLG+I G V +F   E L  PH+GW
Sbjct: 59  KETIYKIVDDRVPFLGICLGMQILFEESEEKRGIKGLGIIKGNVIKFKDVEKL--PHMGW 116

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N+++I KD  L +G  +  + YFVHSYH  P   ++D I     YG  F S I+  N+ A
Sbjct: 117 NSVKIVKDCPLFEGIKNNSYFYFVHSYHVNP---DEDCIVGKTEYGREFPSVINKDNVFA 173

Query: 735 VQFHPEKSGATGLNIFENFL 794
            QFHPEKSG  GL I ENF+
Sbjct: 174 TQFHPEKSGKIGLKIIENFV 193

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>Q9K6Z4:HIS5_BACHD Imidazole glycerol phosphate synthase subunit hisH - Bacillus|
           halodurans
          Length = 214

 Score =  160 bits (405), Expect = 2e-38
 Identities = 88/211 (41%), Positives = 127/211 (60%), Gaps = 5/211 (2%)
 Frame = +3

Query: 204 LLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGMAD 383
           ++DYG GN+ SV  A+  L ++      PE++  AD L+ PGVG+F  AM +LN TG+  
Sbjct: 4   IIDYGMGNLHSVSKALERLSWSYIVSEQPEELQKADGLILPGVGSFHDAMSILNETGLTA 63

Query: 384 ALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFD--SSEGLI--VPHI 551
            +++++   +P LGICLG+QLLF+ SEEN    GL ++PG V RF   +++G    VPH+
Sbjct: 64  FIKDWVDEGKPLLGICLGMQLLFEESEENKRTKGLSLLPGRVIRFPGVATDGSTYKVPHM 123

Query: 552 GWNALQITKDTQ-LLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNI 728
           GWN L   K    LL   +  HVYFVHSY  + +DA+ D +  T +Y E+  + +  GNI
Sbjct: 124 GWNQLTFRKPNHPLLTDVEEGHVYFVHSY-VVKTDAD-DVLLATSHYYETVPAVVGRGNI 181

Query: 729 QAVQFHPEKSGATGLNIFENFLSPNSSGAKA 821
              QFHPEKS   G++I  N+ +    G KA
Sbjct: 182 LGTQFHPEKSSNVGMSILRNYGAMVEKGVKA 212

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>Q8Y9G3:HIS5_LISMO Imidazole glycerol phosphate synthase subunit hisH - Listeria|
           monocytogenes
          Length = 208

 Score =  160 bits (404), Expect = 2e-38
 Identities = 80/198 (40%), Positives = 115/198 (58%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DY  GN +S+  A+  +G   +      +I  AD ++ PGVGA+  AM  L R G+
Sbjct: 2   IVIIDYDTGNTKSISKALDFIGLQNKISSDATEISQADGVILPGVGAYPEAMKELTRRGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              L+E     +P LG+CLG+QLL +SS E+   +GLG+IPG V +        VPH+GW
Sbjct: 62  NKTLKEIAAGGKPILGVCLGMQLLLESSNEHSFTNGLGLIPGHVEKLPEDPEFAVPHMGW 121

Query: 558 NALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQAV 737
           N LQI + T L +  DG++VY+VHSY+A   +  +++I  T  Y       I+ GNI   
Sbjct: 122 NQLQIKRATPLTKQLDGEYVYYVHSYYA---NCPEEYIIATSGYSIEVPGMINKGNIYGA 178

Query: 738 QFHPEKSGATGLNIFENF 791
           QFHPEKSG  GL I + F
Sbjct: 179 QFHPEKSGQIGLEILKGF 196

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>Q3Z7F2:HIS5_DEHE1 Imidazole glycerol phosphate synthase subunit hisH -|
           Dehalococcoides ethenogenes (strain 195)
          Length = 205

 Score =  160 bits (404), Expect = 2e-38
 Identities = 84/199 (42%), Positives = 120/199 (60%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+DYG GN++SV NAI  LG+  +   SPE+IL+A+ ++ PGVGA    M  L   G+
Sbjct: 2   IALVDYGGGNLKSVANAIHALGYEFKLTSSPEEILSAEAVILPGVGAAADTMAGLQSKGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
             A++E +  D P L IC+G+Q+LFD + E      LG++ G V+R    EGL +P +GW
Sbjct: 62  DKAIKELVARDIPLLAICVGMQVLFDYTAEGDNTKCLGILKGDVKRL--PEGLKIPQMGW 119

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L+      + +G  DG   YFVHSY+A P+D     I  T +YG  F S +    + A
Sbjct: 120 NQLKQRVSHPIFEGIPDGIDFYFVHSYYASPADPG--IIGATTDYGVDFCSLVISKRLIA 177

Query: 735 VQFHPEKSGATGLNIFENF 791
            QFHPEKSG+ GL +++NF
Sbjct: 178 TQFHPEKSGSYGLKLYQNF 196

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>Q7P0F1:HIS5_CHRVO Imidazole glycerol phosphate synthase subunit hisH -|
           Chromobacterium violaceum
          Length = 212

 Score =  160 bits (404), Expect = 2e-38
 Identities = 95/212 (44%), Positives = 127/212 (59%), Gaps = 12/212 (5%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDV---RSPEDILAADRLVFPGVGAFGSAMDVLNR 368
           V ++DYG GN+ SV  +++ +  N  D+   R PE ++ AD++VFPG GA    M  LNR
Sbjct: 3   VAVIDYGMGNLHSVLKSLQAVNENGADIFLTRDPEAVVKADKVVFPGQGAMPDCMRELNR 62

Query: 369 TGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEG 533
            G+A+A+RE     +PF GIC+G QLLF+ SEE G  +GLG+ PG V RF        E 
Sbjct: 63  HGLAEAVRE-TTQSKPFFGICVGAQLLFEHSEE-GDTAGLGLFPGKVVRFADDQVAGGER 120

Query: 534 LIVPHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLT---CNYGESF 701
           L VPH+GWN +  T+   L  G ADG+  YFVHSYH  P+DA     +LT    +Y + F
Sbjct: 121 LKVPHMGWNQVYQTRSHPLFAGIADGERFYFVHSYHFAPADA-----ALTLAESDYPQRF 175

Query: 702 ISSISMGNIQAVQFHPEKSGATGLNIFENFLS 797
              +  GNI A QFH EKS   GL + +NFL+
Sbjct: 176 ACIVGRGNIFATQFHTEKSHRAGLQMMKNFLA 207

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>Q81G04:HIS5_BACCR Imidazole glycerol phosphate synthase subunit hisH - Bacillus|
           cereus (strain ATCC 14579 / DSM 31)
          Length = 209

 Score =  160 bits (404), Expect = 2e-38
 Identities = 82/199 (41%), Positives = 120/199 (60%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+RSV  A++++G         ++IL +D ++ PGVGAF  AMDVL    +
Sbjct: 2   IAIIDYGMGNIRSVEQALKYIGAEYIVTSDKKEILRSDGVILPGVGAFPKAMDVLEERDL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              L+E   + +P LGICLG+QLLF+ SEE    SGLG++PG +R+   S    +PH+GW
Sbjct: 62  VCVLKEVCDIGKPLLGICLGMQLLFERSEELKDCSGLGLLPGEIRKLKVS--YKIPHMGW 119

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L+  ++  L  G  DG  VY+VHSY+A   D   + +    +YG      ++ GN+  
Sbjct: 120 NELRKEREFPLWNGLVDGSFVYYVHSYYA---DCPDEIVCGVSDYGMQVPGFVAKGNVFG 176

Query: 735 VQFHPEKSGATGLNIFENF 791
            QFHPEKSG  G+ I +NF
Sbjct: 177 AQFHPEKSGEIGMQILKNF 195

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>Q7SIB9:HIS6_THET8 Imidazole glycerol phosphate synthase subunit hisF - Thermus|
            thermophilus (strain HB8 / ATCC 27634 / DSM 579)
          Length = 252

 Score =  159 bits (403), Expect = 3e-38
 Identities = 120/316 (37%), Positives = 165/316 (52%), Gaps = 3/316 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR++ CLDV +       V KG  +          +R+ G PVE A  Y   GADE+ 
Sbjct: 3    LAKRIVPCLDVHAGR-----VVKGVNF--------VNLRDAGDPVEAARAYDEAGADELV 49

Query: 1026 FLNITGF---RAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASE 1196
            FL+I+     RA       +L+V+   +E+VF+PLTVGGG+R           SLE A +
Sbjct: 50   FLDISATHEERAI------LLDVVARVAERVFIPLTVGGGVR-----------SLEDARK 92

Query: 1197 YFRSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSP 1376
               SGADK+S+ S AV   E             + +++  +G QAVV++ID R       
Sbjct: 93   LLLSGADKVSVNSAAVRRPEL------------IRELADHFGAQAVVLAIDARW------ 134

Query: 1377 DEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDC 1556
                        +G   E +      V+GGR    + A E A    ELGAGEILL  +D 
Sbjct: 135  ------------RGDFPEVH------VAGGRVPTGLHAVEWAVKGVELGAGEILLTSMDR 176

Query: 1557 DGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPI 1736
            DG   G+D+ L +MV++AV +PVIAS GAG +EHF E F+   A AALAA +FH  E+PI
Sbjct: 177  DGTKEGYDLRLTRMVAEAVGVPVIASGGAGRMEHFLEAFQ-AGAEAALAASVFHFGEIPI 235

Query: 1737 LAVKEHLVDAGVEVRM 1784
              +K +L + GV VR+
Sbjct: 236  PKLKRYLAEKGVHVRL 251

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>Q87UG4:HIS6_PSESM Imidazole glycerol phosphate synthase subunit hisF - Pseudomonas|
            syringae pv. tomato
          Length = 256

 Score =  159 bits (403), Expect = 3e-38
 Identities = 117/312 (37%), Positives = 162/312 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG +++         +R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDV---DNGRVV--KGVKFE--------NIRDAGDPVEIARRYDEQGADEIT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D  +  V R AS+ VF+PLTVGGG+R   D                 
Sbjct: 50   FLDITA--SVDGRDTTLHTVERMASQ-VFIPLTVGGGVRTVQD-----------IRNLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AVF  E   +   +            +G+Q +VV+ID +RV        
Sbjct: 96   AGADKVSINTAAVFNPEFVGEAAAR------------FGSQCIVVAIDAKRV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                      GP GE   W +    GGR    + A   AK +E+LGAGEILL  +D DG 
Sbjct: 136  ---------SGP-GEAPRW-EIFTHGGRKPTGLDAVLWAKKMEDLGAGEILLTSMDQDGM 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ + + +SDA+ IPVIAS G G +EH +    + +ASA LAA IFH  E  +   
Sbjct: 185  KNGFDLGVTRAISDALGIPVIASGGVGNLEHLAAGVIEGHASAVLAASIFHFGEYTVPEA 244

Query: 1746 KEHLVDAGVEVR 1781
            K ++   G+ VR
Sbjct: 245  KAYMASRGIVVR 256

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>Q3IUP8:HIS5_NATPD Imidazole glycerol phosphate synthase subunit hisH - Natronomonas|
           pharaonis (strain DSM 2160 / ATCC 35678)
          Length = 215

 Score =  159 bits (403), Expect = 3e-38
 Identities = 90/206 (43%), Positives = 118/206 (57%), Gaps = 7/206 (3%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V L+DYG GN+RSV   +   G  +     P+D  AAD +V PGVGAF   M+  N    
Sbjct: 10  VVLVDYGLGNLRSVTRGLERAGAEVTLSADPDDFSAADGIVLPGVGAFSEGME--NAGPF 67

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEE-----NGPVSGLGVIPGVVRRFDSSEGLIV 542
            +AL       +P  GICLG+Q+L  SSEE      G V GL ++PG   RFD  EG  V
Sbjct: 68  REALVAAAADGQPLFGICLGMQMLLTSSEEAETVGQGDVRGLDLVPGRNVRFD--EGQKV 125

Query: 543 PHIGWNALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESF--ISSIS 716
           PH+GWN L + +D  +++G DG++ YFVHSY+A P D     +  T +Y   F  I +  
Sbjct: 126 PHMGWNELNVARDHPIVEGIDGEYAYFVHSYYAAPDDDAA--VVATTDYSVEFPAIVANE 183

Query: 717 MGNIQAVQFHPEKSGATGLNIFENFL 794
            GN+   QFHPEKSG TGL I +NF+
Sbjct: 184 AGNVFGTQFHPEKSGETGLQILQNFV 209

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>Q9X0C6:HIS6_THEMA Imidazole glycerol phosphate synthase subunit hisF - Thermotoga|
            maritima
          Length = 253

 Score =  159 bits (402), Expect = 4e-38
 Identities = 118/314 (37%), Positives = 160/314 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+IACLDV+     D  V KG  ++         +R+ G PVEL   Y   G DE+ 
Sbjct: 2    LAKRIIACLDVK-----DGRVVKGTNFE--------NLRDSGDPVELGKFYSEIGIDELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       MLE++   +E++ +P TVGGGI DF           E ASE   
Sbjct: 49   FLDIT---ASVEKRKTMLELVEKVAEQIDIPFTVGGGIHDF-----------ETASELIL 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+SI + AV               S + QI++ +G+QAVVV+ID +RV      + 
Sbjct: 95   RGADKVSINTAAV------------ENPSLITQIAQTFGSQAVVVAIDAKRV------DG 136

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
            +F     S K   G                  I   +    VE+ GAGEILL  ID DG 
Sbjct: 137  EFMVFTYSGKKNTG------------------ILLRDWVVEVEKRGAGEILLTSIDRDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D ++I+ V    T+P+IAS GAG +EHF E F    A AALAA +FH +E+ +  +
Sbjct: 179  KSGYDTEMIRFVRPLTTLPIIASGGAGKMEHFLEAF-LAGADAALAASVFHFREIDVREL 237

Query: 1746 KEHLVDAGVEVRMQ 1787
            KE+L   GV VR++
Sbjct: 238  KEYLKKHGVNVRLE 251

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>Q88R41:HIS6_PSEPK Imidazole glycerol phosphate synthase subunit hisF - Pseudomonas|
            putida (strain KT2440)
          Length = 256

 Score =  159 bits (402), Expect = 4e-38
 Identities = 116/312 (37%), Positives = 163/312 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG +++         +R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDV---DNGRVV--KGVKFE--------NIRDAGDPVEIARRYDEQGADEIT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D  +  V R AS+ VF+PLTVGGG+R   D                 
Sbjct: 50   FLDITA--SVDGRDTTLHTVERMASQ-VFIPLTVGGGVRTVQD-----------IRNLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AVF  E   +   +            +G+Q +VV+ID ++V        
Sbjct: 96   AGADKVSINTAAVFNPEFVGEAADR------------FGSQCIVVAIDAKKV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                      GP GE   W +    GGR    + A E AK +E LGAGEILL  +D DG 
Sbjct: 136  ---------SGP-GEAPRW-EIFTHGGRKPTGLDAVEWAKKMEGLGAGEILLTSMDQDGM 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ + + +SDA+ IPVIAS G G ++H ++   + +ASA LAA IFH  E  +   
Sbjct: 185  KNGFDLGVTRAISDALGIPVIASGGVGNLQHLADGILEGHASAVLAASIFHFGEYTVPEA 244

Query: 1746 KEHLVDAGVEVR 1781
            K ++   G+ VR
Sbjct: 245  KAYMASRGIVVR 256

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>Q39K85:HIS6_BURS3 Imidazole glycerol phosphate synthase subunit hisF - Burkholderia sp.|
            (strain 383) (Burkholderia cepacia (strain ATCC 17760 /
            NCIB 9086 / R18194))
          Length = 257

 Score =  159 bits (402), Expect = 4e-38
 Identities = 115/313 (36%), Positives = 160/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV +       V KG  +         E+R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDVTAGR-----VVKGVNF--------VELRDAGDPVEIARRYDDQGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT        DL +L ++   + +VF+PLTVGGG+R           ++E       
Sbjct: 50   FLDITA--TSDQRDL-ILPIIEAVASQVFIPLTVGGGVR-----------AVEDVRRLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV   +       K            YG+Q +VV+ID +RV   S D  
Sbjct: 96   AGADKVSMNSSAVANPQLVRDAADK------------YGSQCIVVAIDAKRV---SAD-- 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W   T  GGR +  + A E A+ + ELGAGEILL  +D DG 
Sbjct: 139  -------------GETPRWEVFT-HGGRKNTGLDAIEWARKMAELGAGEILLTSMDRDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + VSDAV +PVIAS G G+++H ++  +   A A LAA IFH  E  +   
Sbjct: 185  KSGFDLALTRGVSDAVPVPVIASGGVGSLQHLADGIKDGRADAVLAASIFHYGEHTVGEA 244

Query: 1746 KEHLVDAGVEVRM 1784
            K  + D G+ VR+
Sbjct: 245  KRFMADQGIPVRL 257

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>Q63Q92:HIS6_BURPS Imidazole glycerol phosphate synthase subunit hisF - Burkholderia|
            pseudomallei (Pseudomonas pseudomallei)
          Length = 257

 Score =  159 bits (402), Expect = 4e-38
 Identities = 114/313 (36%), Positives = 159/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV +       V KG  +         E+R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDVTAGR-----VVKGVNF--------VELRDAGDPVEIARRYDAQGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   +L ++   + +VF+PLTVGGG+R           ++E       
Sbjct: 50   FLDIT---ATSDGRDLILPIIEAVASQVFIPLTVGGGVR-----------AVEDVRRLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV                 +   +  YG+Q +VV+ID +RV   S D  
Sbjct: 96   AGADKVSMNSSAV------------ANPPLVRDAADKYGSQCIVVAIDAKRV---SAD-- 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W   T  GGR    + A E A+ + ELGAGEILL  +D DG 
Sbjct: 139  -------------GEPPRWEVFT-HGGRKGTGLDAVEWARKMAELGAGEILLTSMDRDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + VSDAV +PVIAS G G++EH +    + +A A LAA IFH  E  +   
Sbjct: 185  KAGFDLALTRAVSDAVPVPVIASGGVGSLEHLAAGITEGHADAVLAASIFHYGEHTVGEA 244

Query: 1746 KEHLVDAGVEVRM 1784
            K  + + G+ VR+
Sbjct: 245  KRFMAERGIAVRL 257

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>Q3JN02:HIS6_BURP1 Imidazole glycerol phosphate synthase subunit hisF - Burkholderia|
            pseudomallei (strain 1710b)
          Length = 257

 Score =  159 bits (402), Expect = 4e-38
 Identities = 114/313 (36%), Positives = 159/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV +       V KG  +         E+R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDVTAGR-----VVKGVNF--------VELRDAGDPVEIARRYDAQGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   +L ++   + +VF+PLTVGGG+R           ++E       
Sbjct: 50   FLDIT---ATSDGRDLILPIIEAVASQVFIPLTVGGGVR-----------AVEDVRRLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV                 +   +  YG+Q +VV+ID +RV   S D  
Sbjct: 96   AGADKVSMNSSAV------------ANPPLVRDAADKYGSQCIVVAIDAKRV---SAD-- 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W   T  GGR    + A E A+ + ELGAGEILL  +D DG 
Sbjct: 139  -------------GEPPRWEVFT-HGGRKGTGLDAVEWARKMAELGAGEILLTSMDRDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + VSDAV +PVIAS G G++EH +    + +A A LAA IFH  E  +   
Sbjct: 185  KAGFDLALTRAVSDAVPVPVIASGGVGSLEHLAAGITEGHADAVLAASIFHYGEHTVGEA 244

Query: 1746 KEHLVDAGVEVRM 1784
            K  + + G+ VR+
Sbjct: 245  KRFMAERGIAVRL 257

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>Q722Y5:HIS5_LISMF Imidazole glycerol phosphate synthase subunit hisH - Listeria|
           monocytogenes serotype 4b (strain F2365)
          Length = 208

 Score =  159 bits (402), Expect = 4e-38
 Identities = 81/198 (40%), Positives = 111/198 (56%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DY  GN +S+  A+  +G   +      +I  AD ++ PGVGA+  AM  L R G+
Sbjct: 2   IVIIDYDTGNTKSISKALDFIGLQNKISSDKTEIAQADGVILPGVGAYPEAMQELTRRGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              L+E     +P LG+CLG+QLL +SS E+    GLG+IPG V          VPH+GW
Sbjct: 62  DKTLKEIATAGKPILGVCLGMQLLLESSNEHSYTKGLGLIPGHVEMLPDESEFAVPHMGW 121

Query: 558 NALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQAV 737
           N LQI + T L Q   G++VY+VHSY+A   +A   +I  T  Y       I+ GNI   
Sbjct: 122 NQLQIKRTTPLTQNIAGEYVYYVHSYYANCPEA---YIIATSGYSIDIPGMINNGNIYGA 178

Query: 738 QFHPEKSGATGLNIFENF 791
           QFHPEKSG  GL I + F
Sbjct: 179 QFHPEKSGQIGLEILKGF 196

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>Q5JFU8:HIS6_PYRKO Imidazole glycerol phosphate synthase subunit hisF - Pyrococcus|
            kodakaraensis (Thermococcus kodakaraensis)
          Length = 252

 Score =  159 bits (401), Expect = 5e-38
 Identities = 119/313 (38%), Positives = 161/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+IA LD+R+       V KG ++        + +R+ G PVELA +Y  +G DE+ 
Sbjct: 2    LAKRIIAALDIRAGR-----VVKGIKF--------RNIRDAGDPVELARRYESEGIDEIV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT       G L  L+++   +E+++VP TVGGGI+           S E A E  +
Sbjct: 49   FLDITASHE-KRGIL--LDLVERVAEEIYVPFTVGGGIK-----------SAEEAGEIIK 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+ + + AV   E             + +I+ + G+  +VV+ID +          
Sbjct: 95   RGADKVFVNTAAVERPEL------------VGEIAELVGSANLVVAIDAKW--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                      G   E Y        GGR  R I A E A+ VEELGAGEILL  +D DG 
Sbjct: 134  ---------NGSFWEVYT------HGGRKPRGIDAVEWARKVEELGAGEILLTSMDTDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI L + V++AV IPVIAS GAG  EHF E F K  A AALAA IFH  E  +  +
Sbjct: 179  KEGFDIPLTRAVANAVDIPVIASGGAGRPEHFYEAF-KAGAEAALAASIFHYGEYTVGQL 237

Query: 1746 KEHLVDAGVEVRM 1784
            K  L + G+ VR+
Sbjct: 238  KGFLAERGIPVRL 250

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>Q9HNI6:HIS5_HALSA Imidazole glycerol phosphate synthase subunit hisH - Halobacterium|
           salinarium (Halobacterium halobium)
          Length = 218

 Score =  159 bits (401), Expect = 5e-38
 Identities = 89/207 (42%), Positives = 120/207 (57%), Gaps = 7/207 (3%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTG 374
           ++ ++DYG GN+RSV   +     ++  V  P  +  AD +V PGVGAFG  M+  N   
Sbjct: 12  SIVVVDYGLGNLRSVTRGLERASADVSIVGDPGALDDADGIVLPGVGAFGDGME--NAGP 69

Query: 375 MADALREYIRMDRPFLGICLGLQLLFDSSEE-----NGPVSGLGVIPGVVRRFDSSEGLI 539
             DAL +     RP  GICLG+Q+L  SSEE      G   GL +IPG   RF  +  + 
Sbjct: 70  FRDALTDAADEGRPLFGICLGMQMLLSSSEEADHEGQGDARGLDLIPGRNVRFTGT--VK 127

Query: 540 VPHIGWNALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSIS- 716
           VPH+GWN L +T+D  L+ G DG++ YFVHSY+A P D     +    +YGE F + ++ 
Sbjct: 128 VPHMGWNELAVTRDHPLVGGVDGEYAYFVHSYYAAPDDPGH--VVAETDYGERFPAVVAN 185

Query: 717 -MGNIQAVQFHPEKSGATGLNIFENFL 794
             GN+   QFHPEKSGATGL I  NF+
Sbjct: 186 DAGNVFGTQFHPEKSGATGLRILRNFV 212

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>Q31E64:HIS6_THICR Imidazole glycerol phosphate synthase subunit hisF - Thiomicrospira|
            crunogena (strain XCL-2)
          Length = 257

 Score =  158 bits (400), Expect = 7e-38
 Identities = 112/313 (35%), Positives = 162/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG Q+         ++R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDV---DNGRVV--KGVQF--------VDIRDAGDPVEVAKRYDEQGADEIT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       ++ V+   + +VF+PLTVGGGIR           S+E       
Sbjct: 50   FLDIT---ATAHERDTIVHVVEEVASQVFIPLTVGGGIR-----------SIEDVRTMLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK++I S A+F              + +++    +G+Q +VV+ID ++V        
Sbjct: 96   AGADKVAINSAAIF------------NPAFVKEACDTFGSQCIVVAIDAKKV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                       P GE   W +    GGR    I A E AK +E LGAGE+L+  +D DG 
Sbjct: 136  ----------SPKGEPDKW-EIFTHGGRKETGIDAVEWAKEMETLGAGELLVTSMDKDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + +SD+V IPVIAS G G +    +   + +A A LAA IFH  E  +   
Sbjct: 185  KSGFDLALTRTISDSVKIPVIASGGVGKLSDLCDGITQGHAEAVLAASIFHFGEHTVQEA 244

Query: 1746 KEHLVDAGVEVRM 1784
            K+ +   G+EVR+
Sbjct: 245  KQAMQKEGIEVRL 257

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>Q4ZLQ2:HIS6_PSEU2 Imidazole glycerol phosphate synthase subunit hisF - Pseudomonas|
            syringae pv. syringae (strain B728a)
          Length = 256

 Score =  158 bits (400), Expect = 7e-38
 Identities = 116/312 (37%), Positives = 162/312 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG +++         +R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDV---DNGRVV--KGVKFE--------NIRDAGDPVEIARRYDEQGADEIT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D  +  V R AS+ VF+PLTVGGG+R   D                 
Sbjct: 50   FLDITA--SVDGRDTTLHTVERMASQ-VFIPLTVGGGVRTVQD-----------IRNLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AVF  E   +   +            +G+Q +VV+ID ++V        
Sbjct: 96   AGADKVSINTAAVFNPEFVGEAAAR------------FGSQCIVVAIDAKKV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                      GP GE   W +    GGR    + A   AK +E+LGAGEILL  +D DG 
Sbjct: 136  ---------SGP-GETPRW-EIFTHGGRKPTGLDAVLWAKKMEDLGAGEILLTSMDQDGM 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ + + +SDA+ IPVIAS G G +EH +    + +ASA LAA IFH  E  +   
Sbjct: 185  KNGFDLGVTRAISDALGIPVIASGGVGNLEHLAAGVIEGHASAVLAASIFHFGEYTVPEA 244

Query: 1746 KEHLVDAGVEVR 1781
            K ++   G+ VR
Sbjct: 245  KAYMASRGIVVR 256

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>Q3KJI5:HIS6_PSEPF Imidazole glycerol phosphate synthase subunit hisF - Pseudomonas|
            fluorescens (strain PfO-1)
          Length = 256

 Score =  158 bits (400), Expect = 7e-38
 Identities = 115/312 (36%), Positives = 165/312 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG +++         +R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDV---DNGRVV--KGVKFE--------NIRDAGDPVEIARRYDEQGADEIT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D  +  V R AS+ VF+PLTVGGG+R   D                 
Sbjct: 50   FLDITA--SVDGRDTTLHTVERMASQ-VFIPLTVGGGVRTVQD-----------IRNLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AVF  E             + + ++ +G+Q +VV+ID ++V        
Sbjct: 96   AGADKVSINTAAVFNPEF------------VGEAAQHFGSQCIVVAIDAKKV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                      GP GE   W +    GGR    + A E AK +E LGAGEILL  +D DG 
Sbjct: 136  ---------SGP-GETPRW-EIFTHGGRKPTGLDAVEWAKKMEGLGAGEILLTSMDQDGM 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ + + +SDA+ IPVIAS G G ++H ++   + +ASA LAA IFH  E  +   
Sbjct: 185  KNGFDLGVTRAISDALGIPVIASGGVGNLQHLADGILEGHASAVLAASIFHFGEYTVQEA 244

Query: 1746 KEHLVDAGVEVR 1781
            K ++   G+ +R
Sbjct: 245  KAYMSKRGIVMR 256

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>Q48C81:HIS6_PSE14 Imidazole glycerol phosphate synthase subunit hisF - Pseudomonas|
            syringae pv. phaseolicola (strain 1448A / Race 6)
          Length = 256

 Score =  158 bits (400), Expect = 7e-38
 Identities = 116/312 (37%), Positives = 162/312 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG +++         +R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDV---DNGRVV--KGVKFE--------NIRDAGDPVEIARRYDEQGADEIT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D  +  V R AS+ VF+PLTVGGG+R   D                 
Sbjct: 50   FLDITA--SVDGRDTTLHTVERMASQ-VFIPLTVGGGVRTVQD-----------IRNLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AVF  E   +   +            +G+Q +VV+ID ++V        
Sbjct: 96   AGADKVSINTAAVFNPEFVGEAAAR------------FGSQCIVVAIDAKKV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                      GP GE   W +    GGR    + A   AK +E+LGAGEILL  +D DG 
Sbjct: 136  ---------SGP-GETPRW-EIFTHGGRKPTGLDAVLWAKKMEDLGAGEILLTSMDQDGM 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ + + +SDA+ IPVIAS G G +EH +    + +ASA LAA IFH  E  +   
Sbjct: 185  KNGFDLGVTRAISDALGIPVIASGGVGNLEHLAAGVIEGHASAVLAASIFHFGEYTVPEA 244

Query: 1746 KEHLVDAGVEVR 1781
            K ++   G+ VR
Sbjct: 245  KAYMASRGIVVR 256

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>Q5HT90:HIS51_CAMJR Imidazole glycerol phosphate synthase subunit hisH 1 -|
           Campylobacter jejuni (strain RM1221)
          Length = 201

 Score =  158 bits (400), Expect = 7e-38
 Identities = 83/201 (41%), Positives = 118/201 (58%), Gaps = 2/201 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+DY AGN+ SV  A   +G      ++P+D+  AD+L+ PGVG+F  AM  L   G 
Sbjct: 2   IALIDYKAGNLNSVAKAFEKIGAINFIAKNPKDLQKADKLLLPGVGSFKEAMKNLKELGF 61

Query: 378 ADALREYIRMDR-PFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIG 554
            +AL+E + + + P LGICLG+QL  +   E G   GLG I G V +F+    L +PH+G
Sbjct: 62  IEALKEQVLVQKKPILGICLGMQLFLERGYEGGVCEGLGFIEGEVVKFEEDLNLKIPHMG 121

Query: 555 WNALQITKDTQLLQGADGQ-HVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           WN L+I K   L QG D +   YFVHS++    D   +++S    YG  F++S+   +I 
Sbjct: 122 WNELEILKQVPLYQGIDNKSDFYFVHSFYVKCKD---EFVSAKAQYGHKFVASLQKDHIF 178

Query: 732 AVQFHPEKSGATGLNIFENFL 794
           A QFHPEKS   GL + ENF+
Sbjct: 179 ATQFHPEKSQNLGLKLLENFI 199

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>Q5HKP2:HIS6_STAEQ Imidazole glycerol phosphate synthase subunit hisF - Staphylococcus|
            epidermidis (strain ATCC 35984 / RP62A)
          Length = 252

 Score =  157 bits (398), Expect = 1e-37
 Identities = 104/312 (33%), Positives = 158/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KRVI CLDV+     D  V KG Q+        + +R++G PV+LA  Y   GADE+ 
Sbjct: 2    IKKRVIPCLDVK-----DGRVVKGIQF--------QSLRDIGNPVDLALYYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   A   G   M+EV+   ++++F+PLTVGGGI++  D            ++   
Sbjct: 49   FLDISKTEA---GHDLMIEVIEATAKQLFIPLTVGGGIQNLDD-----------ITQLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADKIS+ S A+   E             + Q S  +G Q + ++ID    Y K  ++ 
Sbjct: 95   HGADKISLNSSALKHPEL------------IRQASEKFGRQCICIAIDS--FYDKDRED- 139

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               Y CT  GG+    +  Y+  + VE LGAGE+L+  +  DG 
Sbjct: 140  -------------------YFCTTHGGKKLTDVSVYDWVQEVEHLGAGELLITSMHHDGM 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI+ +  +   V IP+IAS G G  +HF E+F++T+ SA LAA I H +E  +  +
Sbjct: 181  KQGFDIEHLAKIKQLVNIPIIASGGGGNAQHFVELFQQTDVSAGLAASILHDQETTVAEI 240

Query: 1746 KEHLVDAGVEVR 1781
            K+ + + G+ VR
Sbjct: 241  KDKMREGGILVR 252

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>Q62GE5:HIS6_BURMA Imidazole glycerol phosphate synthase subunit hisF - Burkholderia|
            mallei (Pseudomonas mallei)
          Length = 257

 Score =  157 bits (398), Expect = 1e-37
 Identities = 113/313 (36%), Positives = 158/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I C DV +       V KG  +         E+R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCFDVTAGR-----VVKGVNF--------VELRDAGDPVEIARRYDAQGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   +L ++   + +VF+PLTVGGG+R           ++E       
Sbjct: 50   FLDIT---ATSDGRDLILPIIEAVASQVFIPLTVGGGVR-----------AVEDVRRLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV                 +   +  YG+Q +VV+ID +RV   S D  
Sbjct: 96   AGADKVSMNSSAV------------ANPPLVRDAADKYGSQCIVVAIDAKRV---SAD-- 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W   T  GGR    + A E A+ + ELGAGEILL  +D DG 
Sbjct: 139  -------------GEPPRWEVFT-HGGRKGTGLDAVEWARKMAELGAGEILLTSMDRDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + VSDAV +PVIAS G G++EH +    + +A A LAA IFH  E  +   
Sbjct: 185  KAGFDLALTRAVSDAVPVPVIASGGVGSLEHLAAGITEGHADAVLAASIFHYGEHTVGEA 244

Query: 1746 KEHLVDAGVEVRM 1784
            K  + + G+ VR+
Sbjct: 245  KRFMAERGIAVRL 257

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>Q97KI0:HIS5_CLOAB Imidazole glycerol phosphate synthase subunit hisH - Clostridium|
           acetobutylicum
          Length = 203

 Score =  157 bits (398), Expect = 1e-37
 Identities = 81/199 (40%), Positives = 120/199 (60%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DY  GN+ SV+ A  ++G N       ++I  +D ++ PGVGAF  AM  L   G+
Sbjct: 5   IAIIDYDMGNLLSVKKAFDYIGANSFITSDSKEIEKSDAIILPGVGAFPDAMSSLKENGI 64

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              +    +  +PF GICLG+QLLFD SEE     GLG+I G +R+  +     +PH+GW
Sbjct: 65  DKTIINEAKNGKPFAGICLGMQLLFDESEEVTNTKGLGLIGGKIRKMKTE--FKIPHMGW 122

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N+L I ++  +L+G + G +VYFVHSY+A  +D N   ++  C+YG    + +S  NI  
Sbjct: 123 NSLNIPRECNILKGVSKGSYVYFVHSYYAELADKNN--LNAYCDYGTKLPAVVSYKNIFG 180

Query: 735 VQFHPEKSGATGLNIFENF 791
           +QFHPEKSG  GL I +NF
Sbjct: 181 IQFHPEKSGEIGLTILKNF 199

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>Q7V6M5:HIS52_PROMM Imidazole glycerol phosphate synthase subunit hisH 2 -|
           Prochlorococcus marinus (strain MIT 9313)
          Length = 213

 Score =  157 bits (398), Expect = 1e-37
 Identities = 89/206 (43%), Positives = 125/206 (60%), Gaps = 1/206 (0%)
 Frame = +3

Query: 204 LLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGMAD 383
           L+DYG GN+RSV+ A   L   +  VR P D+   D L+ PGVGAF  AM  L +T +  
Sbjct: 7   LIDYGMGNLRSVQIAFERLHKALHIVRQPADLSRCDALILPGVGAFDPAMVHLEQTRLVP 66

Query: 384 ALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGWNA 563
            L+ +++  RP LGICLGLQLLF+SS+E G  +GLG++ G V+R  S++G  +PH+GW A
Sbjct: 67  DLKSWVKGGRPLLGICLGLQLLFESSDE-GNATGLGLLKGHVQRLPSNQGERIPHMGWAA 125

Query: 564 LQITKDTQLLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQAVQ 740
           L+   D  LL   D    +YFVHSY A+PS  N D  ++     ++  + +  G + A Q
Sbjct: 126 LEHRNDCPLLDKEDPDSWMYFVHSYAAVPSQ-NSDLAAIAPFGRDNITAMVWKGRLGACQ 184

Query: 741 FHPEKSGATGLNIFENFLSPNSSGAK 818
           FHPEKS A G  +   +L+   +GAK
Sbjct: 185 FHPEKSAAAGERMLRRWLNWLETGAK 210

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>Q0P8U2:HIS51_CAMJE Imidazole glycerol phosphate synthase subunit hisH 1 -|
           Campylobacter jejuni
          Length = 201

 Score =  157 bits (398), Expect = 1e-37
 Identities = 83/200 (41%), Positives = 117/200 (58%), Gaps = 2/200 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+DY AGN+ SV  A   +G      ++P+D+  AD+L+ PGVG+F  AM  L   G 
Sbjct: 2   IALIDYKAGNLNSVAKAFEKIGAINFIAKNPKDLQKADKLLLPGVGSFKEAMKNLKELGF 61

Query: 378 ADALREYIRMDR-PFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIG 554
            +AL+E + + + P LGICLG+QL  +   E G   GLG I G V +F+    L +PH+G
Sbjct: 62  IEALKEQVLVQKKPILGICLGMQLFLERGYEGGVCEGLGFIEGEVVKFEEDLNLKIPHMG 121

Query: 555 WNALQITKDTQLLQGADGQ-HVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           WN L+I K   L QG D +   YFVHS++    D   +++S    YG  F++S+   +I 
Sbjct: 122 WNELEILKQVPLYQGIDNKSDFYFVHSFYVKCKD---EFVSAKAQYGHKFVASLQKDHIF 178

Query: 732 AVQFHPEKSGATGLNIFENF 791
           A QFHPEKS   GL + ENF
Sbjct: 179 ATQFHPEKSQNLGLKLLENF 198

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>Q603K3:HIS6_METCA Imidazole glycerol phosphate synthase subunit hisF - Methylococcus|
            capsulatus
          Length = 254

 Score =  157 bits (397), Expect = 2e-37
 Identities = 112/312 (35%), Positives = 161/312 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG ++         ++R+ G PVE+A +Y  +GADE++
Sbjct: 2    LAKRIIPCLDV---DNGRVV--KGVRF--------VDIRDAGDPVEIARRYDREGADELA 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       M+ V+   + +VF+PLTVGGGIR   D                 
Sbjct: 49   FLDIT---ASSDDRETMVHVVEQVAGEVFIPLTVGGGIRTLDD-----------IRRMLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AVF  E             + + +  +G+Q +VV+ID ++V        
Sbjct: 95   AGADKVSINTAAVFNPEF------------VREAAERFGSQCIVVAIDAKQV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                          E+   ++    GGR    + A + A+ + ELGAGEILL  +D DG 
Sbjct: 135  -------------SEDPPRWEIFTHGGRKPTGLDAVQWARRMVELGAGEILLTSMDRDGT 181

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + VSDAV +PVIAS G G ++H ++   +  A A LAA IFH  E  +   
Sbjct: 182  RSGFDLGLTRAVSDAVGVPVIASGGVGNLQHLADGILQGRADAVLAASIFHFAEYSLGQA 241

Query: 1746 KEHLVDAGVEVR 1781
            K+ L   G+EVR
Sbjct: 242  KDFLATQGIEVR 253

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>Q9RX89:HIS5_DEIRA Imidazole glycerol phosphate synthase subunit hisH - Deinococcus|
           radiodurans
          Length = 215

 Score =  157 bits (397), Expect = 2e-37
 Identities = 91/202 (45%), Positives = 117/202 (57%), Gaps = 1/202 (0%)
 Frame = +3

Query: 189 ANTVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNR 368
           A  V LLDYGAGNVRS   A+   G  +R   +  D+  A  LV PG G F   M+    
Sbjct: 9   APEVLLLDYGAGNVRSAARALERAGMTVRVTDNAADVPHAPALVVPGQGHFRQVMEAFEH 68

Query: 369 TGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPH 548
            G    + +  R   P LGIC+G+QLLFD SEE   V GLG+I G VR+F  +    VP 
Sbjct: 69  GGFHGPVLDAARAGVPLLGICVGMQLLFDGSEEAPGVPGLGLIAGQVRKFAPAPERKVPQ 128

Query: 549 IGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGN 725
           +GWNAL+   D+ LL+G     + YFVHSY+ +P D      ++T +YG  F S++S GN
Sbjct: 129 MGWNALEARGDSPLLRGLGPDAYAYFVHSYY-VPVDVPVTDGAVT-DYGVPFWSALSRGN 186

Query: 726 IQAVQFHPEKSGATGLNIFENF 791
           + A QFHPEKSGA GL +  NF
Sbjct: 187 LHAAQFHPEKSGAVGLALLANF 208

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>Q47AM3:HIS6_DECAR Imidazole glycerol phosphate synthase subunit hisF - Dechloromonas|
            aromatica (strain RCB)
          Length = 252

 Score =  157 bits (396), Expect = 2e-37
 Identities = 110/313 (35%), Positives = 159/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV +       V KG  +          +R+ G P+E+A +Y   GADEV+
Sbjct: 2    LAKRIIPCLDVTAGR-----VVKGTNF--------VGLRDAGDPIEIARRYNEQGADEVT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D+ +L ++   +E+VF+PLTVGGG+R   D                 
Sbjct: 49   FLDITA--SSDQRDI-ILHIIEACAEQVFIPLTVGGGVRKVED-----------VRRLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + AV   +       K G            +Q +VV+ID ++V   +P + 
Sbjct: 95   AGADKVSMNTAAVQNPDLIFDASSKVG------------SQCIVVAIDAKQV---APGQ- 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                              W+  T  GGR+   + A E AK ++ LGAGEILL  +D DG 
Sbjct: 139  ------------------WHVFT-HGGRNDTGMDAIEWAKKIDALGAGEILLTSMDRDGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + VSDAV IPVIAS G G ++H ++   +  A A LAA IFH  E  +   
Sbjct: 180  KNGFDLALTRAVSDAVKIPVIASGGVGNLQHLADGVTEGRADAVLAASIFHFGEYTVRQA 239

Query: 1746 KEHLVDAGVEVRM 1784
            KE++   G+EVR+
Sbjct: 240  KEYMASRGIEVRL 252

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>Q3SWF1:HIS6_NITWN Imidazole glycerol phosphate synthase subunit hisF - Nitrobacter|
            winogradskyi (strain Nb-255 / ATCC 25391)
          Length = 258

 Score =  156 bits (395), Expect = 3e-37
 Identities = 117/310 (37%), Positives = 160/310 (51%)
 Frame = +3

Query: 855  RVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVSFLN 1034
            RVI CLDV+     D  V KG  +         ++R+ G PVE A  Y   GADE++FL+
Sbjct: 5    RVIPCLDVK-----DGRVVKGVNF--------VDLRDAGDPVEAAIAYDAAGADELTFLD 51

Query: 1035 ITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRSGA 1214
            IT           ML+V+R  +E  F+P+TVGGG+R           ++E      RSGA
Sbjct: 52   ITATHE---NRGIMLDVVRRTAEACFMPVTVGGGVR-----------TIEDIRTLLRSGA 97

Query: 1215 DKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQFR 1394
            DK+SI S AV   E             +++ S  +G+Q +VV+ID +RV          R
Sbjct: 98   DKVSINSAAVSRREF------------VKEASEKFGDQCIVVAIDAKRVS---------R 136

Query: 1395 TVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQGGG 1574
            T         G    W +    GGR S  I A E A+ V  LGAGEILL  +D DG   G
Sbjct: 137  T---------GGTDRW-EIFTHGGRRSTGIDAIEYAQEVASLGAGEILLTSMDRDGTRQG 186

Query: 1575 FDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVKEH 1754
            FD+ L + V+D+V +PVIAS G G ++H  +   + +A+A LAA IFH  E  I   KEH
Sbjct: 187  FDLPLTRRVADSVPVPVIASGGVGNLDHLVDGIREGHATAVLAASIFHFGEFTIRQAKEH 246

Query: 1755 LVDAGVEVRM 1784
            +V AG+ +R+
Sbjct: 247  MVRAGLAMRL 256

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>Q5KVD0:HIS6_GEOKA Imidazole glycerol phosphate synthase subunit hisF - Geobacillus|
            kaustophilus
          Length = 252

 Score =  156 bits (395), Expect = 3e-37
 Identities = 112/312 (35%), Positives = 155/312 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+     D  V KG Q+         ++R+ G PVELA  Y   GADE+ 
Sbjct: 2    ITKRIIPCLDVK-----DGRVVKGVQF--------VQLRDAGDPVELAKAYDEQGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   M++V+   + ++ +P TVGGGI            SLE      R
Sbjct: 49   FLDISASHE---GRKTMVDVVERVAAQLAIPFTVGGGIH-----------SLEDMKRMLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + AV               + + + +  +G+Q +VV+ID +          
Sbjct: 95   AGADKVSLNTAAVLHP------------TLITEGADFFGSQCIVVAIDAK---------- 132

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                          E    ++    GGR++        A+    LGAGEILL  +D DG 
Sbjct: 133  ------------YDETLGSWRVYTHGGRNATNWEVVAWAQEAVRLGAGEILLTSMDADGG 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI+L + VS+AV +PVIAS GAG  EHF E FEK  A AALAA IFH KE  +  V
Sbjct: 181  KNGFDIELTRRVSEAVPVPVIASGGAGKAEHFLEAFEKGKADAALAASIFHYKETSVGQV 240

Query: 1746 KEHLVDAGVEVR 1781
            K +L + GV VR
Sbjct: 241  KAYLKEKGVNVR 252

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>Q7P0E9:HIS6_CHRVO Imidazole glycerol phosphate synthase subunit hisF - Chromobacterium|
            violaceum
          Length = 254

 Score =  156 bits (395), Expect = 3e-37
 Identities = 109/313 (34%), Positives = 164/313 (52%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV +       V KG  +          +R+ G PVE+A +Y   GADE++
Sbjct: 2    LAKRIIPCLDVTAGR-----VVKGVNF--------LGLRDAGDPVEIARRYNEQGADELT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D+ +L V+   +++VF+PLTVGGG+R   D                 
Sbjct: 49   FLDITA--SSDQRDI-ILHVIEAVADQVFIPLTVGGGVRSIAD-----------IRRLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV            T    ++Q S  +GNQ +VV++D + V   +P+  
Sbjct: 95   AGADKVSINTAAV------------THPEFVQQASEHFGNQCIVVALDAKAV---TPEND 139

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
            +                  ++    GGR+   + A E A+ +++LGAGEILL  +D DG 
Sbjct: 140  R------------------WEIFTHGGRNRTGLDAVEWARKMQQLGAGEILLTSMDRDGT 181

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GF++ L + VSDAV IPVIAS G G ++H  +  ++ +A A LAA IFH  E  +   
Sbjct: 182  KAGFNLPLTRAVSDAVNIPVIASGGVGNLQHLVDGVKEGHADAVLAASIFHFGEYTVDQA 241

Query: 1746 KEHLVDAGVEVRM 1784
            K+ +  AG+EVR+
Sbjct: 242  KQAMRAAGIEVRL 254

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>Q7MAS1:HIS6_WOLSU Imidazole glycerol phosphate synthase subunit hisF - Wolinella|
            succinogenes
          Length = 254

 Score =  155 bits (393), Expect = 4e-37
 Identities = 111/313 (35%), Positives = 161/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLD++        V KG  +          +R+ G PVE+A +Y  +GADE++
Sbjct: 4    LAKRIIPCLDIKEGR-----VVKGVNF--------LGLRDAGDPVEVARRYNEEGADEIA 50

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT           M +++R  +++VF+PLTVGGGIR   D     Y+ L        
Sbjct: 51   FLDITATHE---RRDTMCDIVRAVAKEVFIPLTVGGGIRKLED----MYTLLN------- 96

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +G DK+SI S A+               S +++ ++ +G+Q +VV+ID +    KS   V
Sbjct: 97   AGCDKVSINSSAI------------KNPSLIDEGAKRFGSQCIVVAIDAKSRADKSGWNV 144

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                                   ++GGR    I   E  K V E GAGEILL  +D DG 
Sbjct: 145  Y----------------------INGGRIDTGIDLLEWTKEVYERGAGEILLTSMDADGT 182

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D + ++ +S  V IP+IAS GAG +EH  E F  + A AALAA IFH KE+ I+ +
Sbjct: 183  KAGYDCEQLQTLSKLVDIPLIASGGAGTMEHIKEAF-LSGADAALAATIFHYKEIDIMDL 241

Query: 1746 KEHLVDAGVEVRM 1784
            K +L   G+EVR+
Sbjct: 242  KRYLRSEGIEVRL 254

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>Q30NR6:HIS6_THIDN Imidazole glycerol phosphate synthase subunit hisF - Thiomicrospira|
            denitrificans (strain ATCC 33889 / DSM 1351)
          Length = 252

 Score =  155 bits (393), Expect = 4e-37
 Identities = 108/312 (34%), Positives = 165/312 (52%)
 Frame = +3

Query: 849  AKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVSF 1028
            AKR+I CLDV+     D  V KG  +          +R+ G PVE+A +Y  +GADE++F
Sbjct: 5    AKRIIPCLDVK-----DGRVVKGVNF--------VGLRDAGDPVEVAKRYNQEGADEITF 51

Query: 1029 LNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRS 1208
            L+IT   A       +++++   + ++F+PLTVGGGIR   D     Y  L V       
Sbjct: 52   LDIT---ASSDNRDTIVDIVAQVAREIFIPLTVGGGIRKLED----IYRLLNV------- 97

Query: 1209 GADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQ 1388
            G DK+S+ S A+   +             +++ ++ +G+Q +V +ID ++          
Sbjct: 98   GCDKVSVNSAAIKRPQL------------IDESAKRFGSQCIVTAIDVKKT--------- 136

Query: 1389 FRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQG 1568
                        G+ Y  Y   ++GGR    I A E AK V E G+GEILL  +D DG  
Sbjct: 137  ------------GDRYNVY---LNGGRVDTGIDALEWAKEVVERGSGEILLTSMDADGTK 181

Query: 1569 GGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVK 1748
             GF++ + +++S+AV +PVIAS GAG ++H  E FE   A AALAA IFH +E+ I+ +K
Sbjct: 182  AGFELSITQLISEAVNVPVIASGGAGTMKHIKEAFEH-GADAALAATIFHYREIDIMDLK 240

Query: 1749 EHLVDAGVEVRM 1784
             +L D  + VR+
Sbjct: 241  RYLHDNNIPVRL 252

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>Q820Q0:HIS6_NITEU Imidazole glycerol phosphate synthase subunit hisF - Nitrosomonas|
            europaea
          Length = 258

 Score =  155 bits (393), Expect = 4e-37
 Identities = 108/313 (34%), Positives = 159/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLD++     D  V KG  +          +R+ G PVE+A  Y   GADE+ 
Sbjct: 3    LAKRIIPCLDIK-----DGRVVKGVNF--------VSLRDAGDPVEIARSYNEQGADELV 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    DL +L ++   + +VF+PLTVGGG+R   D                 
Sbjct: 50   FLDITA--SSENRDL-ILHIVEKVAAQVFIPLTVGGGVRKAED-----------VRRLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV                 +++ +  YG+Q +V++ID R++   +P+  
Sbjct: 96   AGADKVSINTSAVL------------NPMLIKESADHYGSQCIVIAIDARQIPDANPESP 143

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
            +                  ++    GGR    I A E A+ ++ LGAGEILL  +D DG 
Sbjct: 144  R------------------WEVFTHGGRKPTGIDAIEWAQKIQALGAGEILLTSMDRDGT 185

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + +SD+V +PVIAS G G ++H  E     +A A LAA IFH  E  IL  
Sbjct: 186  RSGFDLTLTRAISDSVDLPVIASGGVGHLDHLVEGILAGHADAVLAASIFHYGEYSILQA 245

Query: 1746 KEHLVDAGVEVRM 1784
            K++L   G+EVR+
Sbjct: 246  KQYLSSHGIEVRL 258

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>Q3J6Q3:HIS5_NITOC Imidazole glycerol phosphate synthase subunit hisH - Nitrosococcus|
           oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 209

 Score =  155 bits (393), Expect = 4e-37
 Identities = 93/208 (44%), Positives = 125/208 (60%), Gaps = 4/208 (1%)
 Frame = +3

Query: 192 NTVTLLDYGAGNVRSVRNAIRHLGFNIR-DVRS-PEDILAADRLVFPGVGAFGSAMDVLN 365
           ++V ++DYG GN+RSV  A+  +   +R DV S P+ I AADR+VFPGVGA    M  L 
Sbjct: 2   SSVAVIDYGMGNLRSVSKALEQVAGKVRIDVTSNPQRIRAADRVVFPGVGAIRDCMHELR 61

Query: 366 RTGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEG-LIV 542
           R  + D +      DRPFLGICLGLQ L + SEEN  V  LG++PG V+RFD+ +  L V
Sbjct: 62  RLNL-DIVVAQCAADRPFLGICLGLQALLELSEENHGVPCLGILPGRVQRFDAVKADLKV 120

Query: 543 PHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISM 719
           PH+GWN     +   L          YFVHSY+ +P + +   ++   +Y  SF S+++ 
Sbjct: 121 PHMGWNQAHQVRAHPLWNAIPQNCRFYFVHSYYTVPDETS--LVASRTDYSTSFASALAR 178

Query: 720 GNIQAVQFHPEKSGATGLNIFENFLSPN 803
            NI AVQFHPEKS   GL +  NFL+ N
Sbjct: 179 DNIFAVQFHPEKSHTFGLQLLANFLTWN 206

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>Q63DX0:HIS5_BACCZ Imidazole glycerol phosphate synthase subunit hisH - Bacillus|
           cereus (strain ZK / E33L)
          Length = 209

 Score =  155 bits (393), Expect = 4e-37
 Identities = 81/199 (40%), Positives = 117/199 (58%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+RSV  A++++G         E+I  +D ++ PGVGAF  AMD+L    +
Sbjct: 2   IAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              L+E  R  +P LGICLG+QLLF+ SEE    +GL ++PGV+R+        +PH+GW
Sbjct: 62  VRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKL--KVPYKIPHMGW 119

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L+   +  L  G  DG  VY+VHSY+A   D   + +    +YG      ++ GNI  
Sbjct: 120 NELKKEGEIALWNGVEDGSFVYYVHSYYA---DCPNEIVYGISDYGVKVPGFVAKGNIYG 176

Query: 735 VQFHPEKSGATGLNIFENF 791
            QFHPEKSG  G+ I +NF
Sbjct: 177 AQFHPEKSGDIGMQILKNF 195

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>Q7VBF5:HIS5_PROMA Imidazole glycerol phosphate synthase subunit hisH -|
           Prochlorococcus marinus
          Length = 213

 Score =  155 bits (392), Expect = 6e-37
 Identities = 80/202 (39%), Positives = 126/202 (62%), Gaps = 2/202 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+DYG GN+ SV  + + L  +++ +  P D+   D L+ PGVG+F  AM  L +T +
Sbjct: 5   IGLIDYGMGNLHSVEQSFKRLNQSLKIISGPNDLSNCDALILPGVGSFDPAMKNLQQTNL 64

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              L++++  ++P LGICLGLQLLF+SS+E G   GLG++ G ++    SE  ++PH+GW
Sbjct: 65  IPELKKWVLNNKPLLGICLGLQLLFESSDE-GKSKGLGLLKGTIKHLPKSEKQLIPHMGW 123

Query: 558 NALQITKDTQLLQ-GADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSIS-MGNIQ 731
             L   K+  L +  +  Q +YFVHSY A+PSD N   I+ + N+G+  I+++     + 
Sbjct: 124 AELNQDKECPLFKSNSSPQWMYFVHSYSAIPSDKND--IASSVNFGDEKITAVVWKKKLA 181

Query: 732 AVQFHPEKSGATGLNIFENFLS 797
           A QFHPEKSG +G  +  N+L+
Sbjct: 182 ACQFHPEKSGRSGELLLSNWLA 203

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>Q5UYV3:HIS5_HALMA Imidazole glycerol phosphate synthase subunit hisH - Haloarcula|
           marismortui (Halobacterium marismortui)
          Length = 232

 Score =  155 bits (392), Expect = 6e-37
 Identities = 91/223 (40%), Positives = 119/223 (53%), Gaps = 24/223 (10%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V ++DYG GN+RSV   +   G N+     P +  AAD +V PGVGAF   MD  N    
Sbjct: 10  VVVVDYGLGNLRSVTRGLERAGANVSLSEDPAEFDAADGIVLPGVGAFSEGMD--NAGPF 67

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEE-----NGPVSGLGVIPGVVRRFDSSEGLIV 542
            +AL E     +P  GICLG+Q+L  +SEE      G   GL +IPG   RF  S    V
Sbjct: 68  REALVEQAEAGKPLFGICLGMQMLLTTSEEADHEGQGDAEGLDLIPGKNVRF--SRDQTV 125

Query: 543 PHIGWNALQITKDTQLLQG-----------------ADGQHVYFVHSYHALPSDANKDWI 671
           PH+GWN L +T+D  L++G                  DG+H YFVHSY+A+P D +    
Sbjct: 126 PHMGWNELDVTRDHPLVEGVDSVGSKTPRADGTGGSVDGEHAYFVHSYYAVPDDESA--T 183

Query: 672 SLTCNYGESFISSIS--MGNIQAVQFHPEKSGATGLNIFENFL 794
             T +YG  F S ++   GN+   QFHPEKSG TGL I  N++
Sbjct: 184 VATTDYGTDFASIVANDAGNVFGTQFHPEKSGETGLRILRNYV 226

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>Q7VSY8:HIS5_BORPE Imidazole glycerol phosphate synthase subunit hisH - Bordetella|
           pertussis
          Length = 225

 Score =  155 bits (392), Expect = 6e-37
 Identities = 94/227 (41%), Positives = 128/227 (56%), Gaps = 26/227 (11%)
 Frame = +3

Query: 192 NTVTLLDYGAGNVRSVRNAIRHLG--FNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLN 365
           +T+ ++DYG GN  SV  A++H     +IR    PE I AADR+VFPG GA    M  LN
Sbjct: 2   STIAIVDYGMGNFHSVARALQHAAPDADIRICNRPEQIDAADRVVFPGQGAMPDCMRTLN 61

Query: 366 RTGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFD-------- 521
            +G+  A+ E     +P +G+C+G Q+LF+ SEE G    LG+ PG VRRF         
Sbjct: 62  ESGLRAAV-ERAAASKPLMGVCVGEQMLFERSEEGGTPC-LGIFPGEVRRFAGPQFADPV 119

Query: 522 ------------SSEGLIVPHIGWNALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANK 662
                       + E L VPH+GWN ++ T+   L +G  DG H YFVHSY+A PSD   
Sbjct: 120 AADQAAAAPPAAARERLKVPHMGWNQVRQTRSHALWEGIPDGTHFYFVHSYYAAPSDP-- 177

Query: 663 DWISLTC---NYGESFISSISMGNIQAVQFHPEKSGATGLNIFENFL 794
              +LT    +YG +F  +++  NI AVQFHPEKS   GL ++ NF+
Sbjct: 178 ---ALTTGVTDYGVAFTCAVAAANIFAVQFHPEKSAEHGLRLYRNFV 221

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>Q2YAU8:HIS5_NITMU Imidazole glycerol phosphate synthase subunit hisH - Nitrosospira|
           multiformis (strain ATCC 25196 / NCIMB 11849)
          Length = 212

 Score =  155 bits (391), Expect = 8e-37
 Identities = 91/209 (43%), Positives = 129/209 (61%), Gaps = 10/209 (4%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFN--IRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRT 371
           + ++DYG GN+RSV  A+ H+     I    +PE +  A+R+V PG GA    +  L+R 
Sbjct: 4   IAIVDYGMGNLRSVAKALEHVAPEAVIAVTNNPEVVRKAERVVVPGQGAMPDCLRELDRL 63

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSS-------E 530
           G+ +A+R+    ++PFLGIC+GLQ+LFDSSEE G VSGLG++PG V+RF +S       +
Sbjct: 64  GLREAVRD-AAANKPFLGICIGLQMLFDSSEE-GNVSGLGIVPGRVKRFPASAMKDEKGQ 121

Query: 531 GLIVPHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFIS 707
            L VPH+GWN +  +    L +  A+    YFVHSY+  P+DA+    S    Y  SF  
Sbjct: 122 KLKVPHMGWNQVHQSVGHSLWKNIANDSRFYFVHSYYVEPADADSAGHSA---YPFSFTC 178

Query: 708 SISMGNIQAVQFHPEKSGATGLNIFENFL 794
           +++  NI AVQFHPEKS A GL +  NF+
Sbjct: 179 AVAKDNIFAVQFHPEKSHAAGLTLLGNFV 207

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>Q7W2Y1:HIS5_BORPA Imidazole glycerol phosphate synthase subunit hisH - Bordetella|
           parapertussis
          Length = 225

 Score =  155 bits (391), Expect = 8e-37
 Identities = 94/227 (41%), Positives = 128/227 (56%), Gaps = 26/227 (11%)
 Frame = +3

Query: 192 NTVTLLDYGAGNVRSVRNAIRHLG--FNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLN 365
           +T+ ++DYG GN  SV  A++H     +IR    PE I AADR+VFPG GA    M  LN
Sbjct: 2   STIAIVDYGMGNFHSVARALQHAAPDADIRICNRPEQIDAADRVVFPGQGAMPDCMRTLN 61

Query: 366 RTGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFD-------- 521
            +G+  A+ E     +P +G+C+G Q+LF+ SEE G    LG+ PG VRRF         
Sbjct: 62  ESGLRAAV-ERAAASKPLMGVCVGEQMLFERSEE-GDTPCLGIFPGEVRRFAGPQFADPV 119

Query: 522 ------------SSEGLIVPHIGWNALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANK 662
                       + E L VPH+GWN ++ T+   L +G  DG H YFVHSY+A PSD   
Sbjct: 120 AADQAAAAPPAAARERLKVPHMGWNQVRQTRSHALWEGIPDGTHFYFVHSYYAAPSDP-- 177

Query: 663 DWISLTC---NYGESFISSISMGNIQAVQFHPEKSGATGLNIFENFL 794
              +LT    +YG +F  +++  NI AVQFHPEKS   GL ++ NF+
Sbjct: 178 ---ALTTGVTDYGVAFTCAVAAANIFAVQFHPEKSAEHGLRLYRNFV 221

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>Q7WDY1:HIS5_BORBR Imidazole glycerol phosphate synthase subunit hisH - Bordetella|
           bronchiseptica (Alcaligenes bronchisepticus)
          Length = 225

 Score =  155 bits (391), Expect = 8e-37
 Identities = 94/227 (41%), Positives = 128/227 (56%), Gaps = 26/227 (11%)
 Frame = +3

Query: 192 NTVTLLDYGAGNVRSVRNAIRHLG--FNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLN 365
           +T+ ++DYG GN  SV  A++H     +IR    PE I AADR+VFPG GA    M  LN
Sbjct: 2   STIAIVDYGMGNFHSVARALQHAAPDADIRICNRPEQIDAADRVVFPGQGAMPDCMRTLN 61

Query: 366 RTGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFD-------- 521
            +G+  A+ E     +P +G+C+G Q+LF+ SEE G    LG+ PG VRRF         
Sbjct: 62  ESGLRAAV-ERAAASKPLMGVCVGEQMLFERSEE-GDTPCLGIFPGEVRRFAGPQFADPV 119

Query: 522 ------------SSEGLIVPHIGWNALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANK 662
                       + E L VPH+GWN ++ T+   L +G  DG H YFVHSY+A PSD   
Sbjct: 120 AADQAAAAPPAAARERLKVPHMGWNQVRQTRSHALWEGIPDGTHFYFVHSYYAAPSDP-- 177

Query: 663 DWISLTC---NYGESFISSISMGNIQAVQFHPEKSGATGLNIFENFL 794
              +LT    +YG +F  +++  NI AVQFHPEKS   GL ++ NF+
Sbjct: 178 ---ALTTGVTDYGVAFTCAVAAANIFAVQFHPEKSAEHGLRLYRNFV 221

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>Q6F7A7:HIS5_ACIAD Imidazole glycerol phosphate synthase subunit hisH - Acinetobacter|
           sp. (strain ADP1)
          Length = 205

 Score =  155 bits (391), Expect = 8e-37
 Identities = 81/204 (39%), Positives = 116/204 (56%), Gaps = 2/204 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + LLDYG GN+ S   A+ H+G  +     P+ I  AD++VFPGVGA    M  ++  G+
Sbjct: 4   IALLDYGMGNLHSAAKALEHVGATVDVTNDPKLIAKADKIVFPGVGAMRDCMQGMHEAGI 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + +R+ +  ++P L IC+G+Q L +SSEENG V  LG+  G V+ F     L VPH+GW
Sbjct: 64  DEVVRQAV-FNKPVLAICVGMQALLESSEENGGVPALGIFEGAVKHFPDLGHLKVPHMGW 122

Query: 558 NALQITKDTQLLQGADGQ--HVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           N +        +     Q    YFVHSY+  P  +  D I+ TC+YG  F ++I   N+ 
Sbjct: 123 NQVYQNDPAHPMWNNIDQDSRFYFVHSYYVEPKQS--DLIAATCDYGLQFCTAIHKDNLF 180

Query: 732 AVQFHPEKSGATGLNIFENFLSPN 803
           A QFHPEKS   GL + +NF+  N
Sbjct: 181 ATQFHPEKSHTAGLQLLKNFVEWN 204

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>A1W0U9:HIS51_CAMJJ Imidazole glycerol phosphate synthase subunit hisH 1 -|
           Campylobacter jejuni subsp. jejuni serotype O:23/36
           (strain 81-176)
          Length = 201

 Score =  155 bits (391), Expect = 8e-37
 Identities = 82/200 (41%), Positives = 116/200 (58%), Gaps = 2/200 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+DY AGN+ SV  A   +G      ++P+D+  AD+L+ PGVG+F  AM  L   G 
Sbjct: 2   IALIDYKAGNLNSVAKAFEKIGAINFIAKNPKDLQKADKLLLPGVGSFKEAMKNLKELGF 61

Query: 378 ADALREYIRMDR-PFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIG 554
            +AL+E + + + P LGICLG+QL  +   E G   GLG I G V +F+    L +PH+G
Sbjct: 62  IEALKEQVLVQKKPILGICLGMQLFLERGYEGGVCEGLGFIEGEVVKFEEDLNLKIPHMG 121

Query: 555 WNALQITKDTQLLQGADGQ-HVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           WN L+I K   L QG + +   YFVHS++    D   +++S    YG  F++S+    I 
Sbjct: 122 WNELEILKQDPLYQGINNKSDFYFVHSFYVKCKD---EFVSAKAQYGHKFVASLQKDRIF 178

Query: 732 AVQFHPEKSGATGLNIFENF 791
           A QFHPEKS   GL + ENF
Sbjct: 179 ATQFHPEKSQNLGLKLLENF 198

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>Q82A99:HIS6_STRAW Imidazole glycerol phosphate synthase subunit hisF - Streptomyces|
            avermitilis
          Length = 251

 Score =  154 bits (390), Expect = 1e-36
 Identities = 113/312 (36%), Positives = 155/312 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LA RVI CLDV   DNG +V  KG  +        + +R+ G PVE+A  Y  +GADE++
Sbjct: 3    LAVRVIPCLDV---DNGRVV--KGVNF--------QNLRDAGDPVEMAKVYDAEGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT             +V+R  +E+VF+PLTVGGG+R   D             +  R
Sbjct: 50   FLDITASSG---NRETTYDVVRRTAEQVFIPLTVGGGVRTPDD-----------VDKLLR 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+ + + A+   E             + +I+  +G Q +V+S+D RR         
Sbjct: 96   AGADKVGVNTAAIARPEL------------IREIAERFGRQVLVLSVDARRT-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E   ++ T  GGR    I A E A    ELGAGEILLN +D DG 
Sbjct: 136  ---------------ESGSFEVTTHGGRKGTGIDAVEWAHRAAELGAGEILLNSMDADGT 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+++I  V   VT+PVIAS GAG ++HF        A A LAA +FH  ++ I  V
Sbjct: 181  KDGYDLEMIAAVRAHVTVPVIASGGAGKLDHFPPAI-AAGADAVLAASVFHFGDLRIGEV 239

Query: 1746 KEHLVDAGVEVR 1781
            KE L  AG  VR
Sbjct: 240  KETLRAAGHPVR 251

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>Q8CQ92:HIS6_STAES Imidazole glycerol phosphate synthase subunit hisF - Staphylococcus|
            epidermidis (strain ATCC 12228)
          Length = 252

 Score =  154 bits (390), Expect = 1e-36
 Identities = 104/312 (33%), Positives = 157/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KRVI CLDV+     D  V KG Q+        + +R++G PV+LA  Y   GADE+ 
Sbjct: 2    IKKRVIPCLDVK-----DGRVVKGIQF--------QSLRDIGNPVDLALYYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   A   G   M+EV+   ++++F+PLTVGGGI++  D            ++   
Sbjct: 49   FLDISKTEA---GHDLMIEVIEATAKQLFIPLTVGGGIQNLDD-----------ITQLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADKIS+ S A+   E             + Q S  +G Q + ++ID    Y K   + 
Sbjct: 95   HGADKISLNSSALKHPEL------------IRQASEKFGRQCICIAIDS--FYDKDRKD- 139

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               Y CT  GG+    +  Y+  + VE LGAGE+L+  +  DG 
Sbjct: 140  -------------------YFCTTHGGKKLTDVRVYDWVQEVELLGAGELLITSMHHDGM 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI+ +  +   V IP+IAS G G  +HF E+F++T+ SA LAA I H +E  +  +
Sbjct: 181  KQGFDIEHLAKIKQLVNIPIIASGGGGNAQHFVELFQQTDVSAGLAASILHDQETTVAEI 240

Query: 1746 KEHLVDAGVEVR 1781
            K+ + + G+ VR
Sbjct: 241  KDKMREGGILVR 252

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>Q81T60:HIS5_BACAN Imidazole glycerol phosphate synthase subunit hisH - Bacillus|
           anthracis
          Length = 209

 Score =  154 bits (390), Expect = 1e-36
 Identities = 80/199 (40%), Positives = 117/199 (58%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+RSV  A++++G         E+I  +D ++ PGVGAF  AMD+L    +
Sbjct: 2   IAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              L+E  R  +P LGICLG+QLLF+ SEE    +GL ++PGV+R+        +PH+GW
Sbjct: 62  VRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKL--KVPYKIPHMGW 119

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L+   +  L  G  DG  VY+VHSY+A   D   + +    +YG      ++ GNI  
Sbjct: 120 NELKKEGEIALWNGVEDGSFVYYVHSYYA---DCPNEIVYGISDYGVKVPGFVAKGNIYG 176

Query: 735 VQFHPEKSGATGLNIFENF 791
            QFHPEKSG  G+ + +NF
Sbjct: 177 AQFHPEKSGDIGMQMLKNF 195

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>Q8DTR3:HIS6_STRMU Imidazole glycerol phosphate synthase subunit hisF - Streptococcus|
            mutans
          Length = 251

 Score =  154 bits (389), Expect = 1e-36
 Identities = 108/312 (34%), Positives = 157/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV+     D  V KG  +          + ++G PV+ A  YY  G DE+ 
Sbjct: 2    LKKRIIPCLDVK-----DGRVVKGVNF--------VNLTDVGDPVDAARAYYEAGCDELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A        ++++R  +++VF+P TVGGGIR   D            ++  +
Sbjct: 49   FLDIT---ATSDNRETTVDMVRHVADQVFIPFTVGGGIRSVDD-----------MNKMLK 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+++ S A+                 ++  +  +G+Q VVV+ID R    K  D+ 
Sbjct: 95   AGADKVAVNSSAI------------ANPQLIKDCAEKFGSQCVVVAIDAR----KEADD- 137

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                             +W+   V+GGR    I      K   +LGAGEILL  +D DG 
Sbjct: 138  -----------------SWH-VYVAGGRKDTGIDLLAWVKEAVQLGAGEILLTSMDKDGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+D++  V+    IP+IAS GAG +EH  E+FEKT A+ ALAA IFH  EV I   
Sbjct: 180  KSGFDLDMLNAVAQLADIPIIASGGAGNMEHMVEIFEKTPATGALAASIFHYGEVSIADT 239

Query: 1746 KEHLVDAGVEVR 1781
            K+ + + G+EVR
Sbjct: 240  KKAMKEHGIEVR 251

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>Q3MEF5:HIS6_ANAVT Imidazole glycerol phosphate synthase subunit hisF - Anabaena|
            variabilis (strain ATCC 29413 / PCC 7937)
          Length = 257

 Score =  154 bits (389), Expect = 1e-36
 Identities = 108/313 (34%), Positives = 161/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L+KR++ CLDV++       V KG  +         ++++ G PVELA  Y   GADE+ 
Sbjct: 2    LSKRILPCLDVKAGR-----VVKGVNF--------VDLKDAGDPVELAKVYNDAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT           +++V+   +E+VF+PLTVGGGI+           SLE      R
Sbjct: 49   FLDITATHE---DRDTIIDVVYRTAEQVFIPLTVGGGIQ-----------SLENVKALLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S AV   E             +++ S  +GNQ +VV+ID RR         
Sbjct: 95   AGADKVSINSAAVRDPEL------------IDRASDRFGNQCIVVAIDARR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                 +V    P  + Y      V GGR++  + A   AK VE+ GAGE+L+  +D DG 
Sbjct: 134  -----RVDPSNPGWDVY------VRGGRENTGLDALSWAKEVEKRGAGELLVTSMDADGT 182

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D++L + ++++V IPVIAS GAG  EH      +  A AAL A + H  ++ +  +
Sbjct: 183  QAGYDLELTRAIAESVEIPVIASGGAGNCEHIYTALTEGKAEAALLASLLHYGQLSVAEI 242

Query: 1746 KEHLVDAGVEVRM 1784
            K +L D  V VR+
Sbjct: 243  KNYLRDCQVPVRL 255

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>P61778:HIS5_BACC1 Imidazole glycerol phosphate synthase subunit hisH - Bacillus|
           cereus (strain ATCC 10987)
          Length = 209

 Score =  154 bits (389), Expect = 1e-36
 Identities = 81/199 (40%), Positives = 116/199 (58%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+RSV  A++H+G         E+I  +D ++ PGVGAF  AMDVL    +
Sbjct: 2   IAIIDYGMGNIRSVEQALKHIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDVLEEKDL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              L+E  R  +P LGICLG+QLLF+ SEE    +GL ++PGV+R+        +PH+GW
Sbjct: 62  VRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKL--KVPYKIPHMGW 119

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L+   +  L  G  DG  VY+VHSY+A   D   + +    +YG      ++  NI  
Sbjct: 120 NELKKEGEIALWNGVEDGSFVYYVHSYYA---DCPNEIVYGISDYGVKVPGFVAKENIYG 176

Query: 735 VQFHPEKSGATGLNIFENF 791
            QFHPEKSG  G+ + +NF
Sbjct: 177 AQFHPEKSGDIGMQMLKNF 195

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>O28019:HIS5_ARCFU Imidazole glycerol phosphate synthase subunit hisH - Archaeoglobus|
           fulgidus
          Length = 197

 Score =  154 bits (389), Expect = 1e-36
 Identities = 86/202 (42%), Positives = 120/202 (59%), Gaps = 2/202 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + +++YG GN++S+  A+  +G  +     PE I  A  +VFPGVGAF SA++ LN    
Sbjct: 2   IAIVNYGVGNLKSISKALETVGAKVSVTSDPEKIKCASGVVFPGVGAFKSAIEKLN---- 57

Query: 378 ADALREYI-RMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIG 554
              +R+ I  ++ P LGICLG+QL    S E G   GL  IPG V RF  S G  VPH+G
Sbjct: 58  --LIRDVIDSLEVPILGICLGMQLFATESTEGGVYRGLDYIPGRVVRFPPSVGK-VPHMG 114

Query: 555 WNALQITKDTQLLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           WN L+IT++ ++L G + G+ VYFVHSY+    D   +++    +YG  F S +   N  
Sbjct: 115 WNTLKITREAEILDGVESGEFVYFVHSYYMQTDD---EFVISKTDYGIDFPSGVERENYI 171

Query: 732 AVQFHPEKSGATGLNIFENFLS 797
             QFHPEKSG  GL I ENF++
Sbjct: 172 GFQFHPEKSGKVGLRILENFVN 193

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>P72138:HIS52_PSEAE Imidazole glycerol phosphate synthase subunit hisH 2 - Pseudomonas|
           aeruginosa
          Length = 202

 Score =  154 bits (389), Expect = 1e-36
 Identities = 82/201 (40%), Positives = 122/201 (60%), Gaps = 2/201 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+ SV N ++ +G   +   S EDI  A++L+ PGVGAF + M  L ++G+
Sbjct: 2   IVVIDYGVGNIASVLNMLKRVGAKAKASDSREDIEQAEKLILPGVGAFDAGMQTLRKSGL 61

Query: 378 ADALREYIRMDR-PFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIG 554
            D L E + + R P +G+CLG Q+L   SEE G   GLG I     RF+  +   VPH+G
Sbjct: 62  VDVLTEQVMIKRKPVMGVCLGSQMLGLRSEE-GAEPGLGWIDMDSVRFERRDDRKVPHMG 120

Query: 555 WNALQITKDTQLLQGADGQ-HVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           WN +    +  +L G + Q   YFVHSY+ +P D   D I L+CNYG+ F ++++  N+ 
Sbjct: 121 WNQVSPQLEHPILSGINEQSRFYFVHSYYMVPKD--PDDILLSCNYGQKFTAAVARDNVF 178

Query: 732 AVQFHPEKSGATGLNIFENFL 794
             QFHPEKS   G+ +F+NF+
Sbjct: 179 GFQFHPEKSHKFGMQLFKNFV 199

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>Q9S2T7:HIS6_STRCO Imidazole glycerol phosphate synthase subunit hisF - Streptomyces|
            coelicolor
          Length = 251

 Score =  154 bits (388), Expect = 2e-36
 Identities = 110/312 (35%), Positives = 157/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LA RVI CLDV   DNG +V  KG  +        + +R+ G PVE+A  Y  +GADE++
Sbjct: 3    LAVRVIPCLDV---DNGRVV--KGVNF--------QNLRDAGDPVEMAKVYDAEGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT             +V+R  +E+VF+PLTVGGG+R   D             +  R
Sbjct: 50   FLDITASSG---NRETTYDVVRRTAEQVFIPLTVGGGVRTAED-----------VDKLLR 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+ + + A+   +             + +I+  +G Q +V+S+D RR         
Sbjct: 96   AGADKVGVNTAAIARPDL------------IREIAERFGRQVLVLSVDARRT-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E   ++ T  GGR    I A E A    ELGAGEILLN +D DG 
Sbjct: 136  ---------------EAGTFEVTTHGGRRGTGIDAVEWAHRAAELGAGEILLNSMDADGT 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D++++  V   V++PVIAS GAG++ HF+   E   A A LAA +FH  ++ I  V
Sbjct: 181  KDGYDLEMLAAVRKHVSVPVIASGGAGSLAHFAPAVE-AGADAVLAASVFHFGDLRIGEV 239

Query: 1746 KEHLVDAGVEVR 1781
            K  L +AG  VR
Sbjct: 240  KTTLREAGHPVR 251

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>Q8NUI3:HIS6_STAAW Imidazole glycerol phosphate synthase subunit hisF - Staphylococcus|
            aureus (strain MW2)
          Length = 252

 Score =  154 bits (388), Expect = 2e-36
 Identities = 107/312 (34%), Positives = 159/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+     D  V KG Q+        K +R++G PV+LA  Y   GADE+ 
Sbjct: 2    IKKRIIPCLDVK-----DGRVVKGIQF--------KGLRDIGNPVDLAMYYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   MLEV+   + ++F+PLTVGGGI+           SL+  ++   
Sbjct: 49   FLDISKTEE---GHSLMLEVIEQTASRLFIPLTVGGGIQ-----------SLDDITQLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ S A+                 ++Q S  +G Q + ++ID            
Sbjct: 95   HGADKVSLNSSAL------------KNPQLIKQASDKFGRQCICIAID------------ 130

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                   S   P  E  A Y CT +GG+    I  Y+  + VE+LGAGE+L+  +  DG 
Sbjct: 131  -------SYYDP--ERKAHYCCT-TGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGM 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI+ +  +   V IP+IAS G G  +HF E+F++T+ SA LAA I H +E  + ++
Sbjct: 181  KQGFDIEHLANIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSI 240

Query: 1746 KEHLVDAGVEVR 1781
            KE +   G+ VR
Sbjct: 241  KEVIRQGGIAVR 252

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>Q6G602:HIS6_STAAS Imidazole glycerol phosphate synthase subunit hisF - Staphylococcus|
            aureus (strain MSSA476)
          Length = 252

 Score =  154 bits (388), Expect = 2e-36
 Identities = 107/312 (34%), Positives = 159/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+     D  V KG Q+        K +R++G PV+LA  Y   GADE+ 
Sbjct: 2    IKKRIIPCLDVK-----DGRVVKGIQF--------KGLRDIGNPVDLAMYYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   MLEV+   + ++F+PLTVGGGI+           SL+  ++   
Sbjct: 49   FLDISKTEE---GHSLMLEVIEQTASRLFIPLTVGGGIQ-----------SLDDITQLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ S A+                 ++Q S  +G Q + ++ID            
Sbjct: 95   HGADKVSLNSSAL------------KNPQLIKQASDKFGRQCICIAID------------ 130

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                   S   P  E  A Y CT +GG+    I  Y+  + VE+LGAGE+L+  +  DG 
Sbjct: 131  -------SYYDP--ERKAHYCCT-TGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGM 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI+ +  +   V IP+IAS G G  +HF E+F++T+ SA LAA I H +E  + ++
Sbjct: 181  KQGFDIEHLANIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSI 240

Query: 1746 KEHLVDAGVEVR 1781
            KE +   G+ VR
Sbjct: 241  KEVIRQGGIAVR 252

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>Q5HCM4:HIS6_STAAC Imidazole glycerol phosphate synthase subunit hisF - Staphylococcus|
            aureus (strain COL)
          Length = 252

 Score =  154 bits (388), Expect = 2e-36
 Identities = 107/312 (34%), Positives = 159/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+     D  V KG Q+        K +R++G PV+LA  Y   GADE+ 
Sbjct: 2    IKKRIIPCLDVK-----DGRVVKGIQF--------KGLRDIGNPVDLAMYYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   MLEV+   + ++F+PLTVGGGI+           SL+  ++   
Sbjct: 49   FLDISKTEE---GHSLMLEVIEQTASRLFIPLTVGGGIQ-----------SLDDITQLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ S A+                 ++Q S  +G Q + ++ID            
Sbjct: 95   HGADKVSLNSSAL------------KNPQLIKQASDKFGRQCICIAID------------ 130

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                   S   P  E  A Y CT +GG+    I  Y+  + VE+LGAGE+L+  +  DG 
Sbjct: 131  -------SYYDP--ERKAHYCCT-TGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGM 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI+ +  +   V IP+IAS G G  +HF E+F++T+ SA LAA I H +E  + ++
Sbjct: 181  KQGFDIEHLANIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSI 240

Query: 1746 KEHLVDAGVEVR 1781
            KE +   G+ VR
Sbjct: 241  KEVIRQGGIAVR 252

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>Q6GDD1:HIS6_STAAR Imidazole glycerol phosphate synthase subunit hisF - Staphylococcus|
            aureus (strain MRSA252)
          Length = 252

 Score =  153 bits (387), Expect = 2e-36
 Identities = 107/312 (34%), Positives = 158/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+     D  V KG Q+        K +R++G PV+LA  Y   GADE+ 
Sbjct: 2    IKKRIIPCLDVK-----DGRVVKGIQF--------KGLRDIGNPVDLAMYYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   MLEV+   + ++F+PLTVGGGI+           SL+  ++   
Sbjct: 49   FLDISKTEE---GHSLMLEVIEQTASRLFIPLTVGGGIQ-----------SLDDITQLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ S A+                 ++Q S  +G Q + ++ID            
Sbjct: 95   HGADKVSLNSSAL------------KNPQLIKQASDKFGRQCICIAID------------ 130

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                   S   P  E  A Y CT  GG+    I  Y+  + VE+LGAGE+L+  +  DG 
Sbjct: 131  -------SYYDP--ERKAHYCCT-HGGKKLTNIKVYDWVQQVEQLGAGELLVTSMGHDGM 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI+ +  +   V IP+IAS G G  +HF E+F++T+ SA LAA I H +E  + ++
Sbjct: 181  KQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSI 240

Query: 1746 KEHLVDAGVEVR 1781
            KE +   G+ VR
Sbjct: 241  KEAIRQGGIAVR 252

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>Q2YZ71:HIS6_STAAB Imidazole glycerol phosphate synthase subunit hisF - Staphylococcus|
            aureus (strain bovine RF122)
          Length = 252

 Score =  153 bits (387), Expect = 2e-36
 Identities = 107/312 (34%), Positives = 158/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+     D  V KG Q+        K +R++G PV+LA  Y   GADE+ 
Sbjct: 2    IKKRIIPCLDVK-----DGRVVKGIQF--------KGLRDIGNPVDLAMYYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   MLEV+   + ++F+PLTVGGGI+           SL+  ++   
Sbjct: 49   FLDISKTEE---GHSLMLEVIEQTASRLFIPLTVGGGIQ-----------SLDDITQLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ S A+                 ++Q S  +G Q + ++ID            
Sbjct: 95   HGADKVSLNSSAL------------KNPQLIKQASDKFGRQCICIAID------------ 130

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                   S   P  E  A Y CT  GG+    I  Y+  + VE+LGAGE+L+  +  DG 
Sbjct: 131  -------SYYDP--ERKAHYCCT-HGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGM 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI+ +  +   V IP+IAS G G  +HF E+F++T+ SA LAA I H +E  + ++
Sbjct: 181  KQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSI 240

Query: 1746 KEHLVDAGVEVR 1781
            KE +   G+ VR
Sbjct: 241  KEVIRQGGIAVR 252

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>Q2RGW2:HIS6_MOOTA Imidazole glycerol phosphate synthase subunit hisF - Moorella|
            thermoacetica (strain ATCC 39073)
          Length = 252

 Score =  153 bits (387), Expect = 2e-36
 Identities = 121/315 (38%), Positives = 158/315 (50%), Gaps = 2/315 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV   D+G +V  KG  +          +R+ G PVELA+ Y  +GADE+ 
Sbjct: 2    LTKRIIPCLDV---DHGRVV--KGTNF--------LNLRDAGDPVELAAAYDREGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   A   G   M++V R  + +VF+P TVGGG+R           SLE       
Sbjct: 49   FLDIS---ASVEGRDIMIDVARRTAAQVFIPFTVGGGLR-----------SLEDIRAMLA 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKIS+ + AV   +             +   +R +G+Q VVV+ID RR         
Sbjct: 95   AGADKISLNTAAVLDPDL------------VATAARRFGSQCVVVAIDARRT-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIG--AYELAKAVEELGAGEILLNCIDCD 1559
                      GP       ++    GGR  RP G  A   A+ VEELGAGEILL  +DCD
Sbjct: 135  ----------GP-----GRWEVYTHGGR--RPTGRDAVAWARQVEELGAGEILLTSMDCD 177

Query: 1560 GQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPIL 1739
            G   G+D++L   VS AV IPVIAS G G +EH  E      A A LAA IFH     I 
Sbjct: 178  GTLDGYDLELTATVSQAVNIPVIASGGVGKLEHLYEGLTAGRADAVLAASIFHFGTYTIK 237

Query: 1740 AVKEHLVDAGVEVRM 1784
              K++L   GV VR+
Sbjct: 238  EAKDYLAARGVPVRL 252

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>O34727:HIS6_BACSU Imidazole glycerol phosphate synthase subunit hisF - Bacillus|
            subtilis
          Length = 252

 Score =  153 bits (387), Expect = 2e-36
 Identities = 111/312 (35%), Positives = 152/312 (48%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+        V KG Q+         E+++ G PVELA  Y  +GADE+ 
Sbjct: 2    ITKRIIPCLDVKEGR-----VVKGIQF--------LELKDAGDPVELAEVYDREGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   M++V+   + K+ +P TVGGGI   +D                R
Sbjct: 49   FLDISASHE---GRKTMVDVVEQVAAKLAIPFTVGGGINQLSD-----------MKTILR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + AV   E             + + +  +G+Q +V++ID +  Y K  D  
Sbjct: 95   AGADKVSVNTAAVLRPEL------------ITEGAEFFGSQCIVLAIDAK--YDKESDT- 139

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               Y+    GGR          AK   + GAGEILL  +D DG+
Sbjct: 140  -------------------YKVYTHGGRKKTDWEVTAWAKEGVKRGAGEILLTSMDSDGE 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD  L K+VS+AV +PVIAS GAG  +H  E F K  A AALAA IFH KE  I  V
Sbjct: 181  KKGFDHTLTKLVSEAVPVPVIASGGAGNAQHMLEAFTKGEADAALAASIFHYKETSIKEV 240

Query: 1746 KEHLVDAGVEVR 1781
            K +L + GV VR
Sbjct: 241  KSYLKEYGVNVR 252

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>Q65EG3:HIS6_BACLD Imidazole glycerol phosphate synthase subunit hisF - Bacillus|
            licheniformis (strain DSM 13 / ATCC 14580)
          Length = 252

 Score =  153 bits (387), Expect = 2e-36
 Identities = 109/312 (34%), Positives = 151/312 (48%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+     D  V KG Q+         E+++ G PVELA  Y  +GADE+ 
Sbjct: 2    ITKRIIPCLDVK-----DGRVVKGVQF--------VELKDAGDPVELAEVYDHEGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   M++V+   + K+ +P TVGGGI    D                R
Sbjct: 49   FLDISASHE---GRKTMVDVVERVAAKLAIPFTVGGGINRLDD-----------MKTILR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + AV   E             + + +  +G+Q +VV+ID +          
Sbjct: 95   AGADKVSVNTAAVLRPEL------------ITEGADFFGSQCIVVAIDAK---------- 132

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E   Y     GGR    + A   AK     GAGEILL  +D DG+
Sbjct: 133  ------------YDPEADLYYVYTHGGRKKTNLEAVSWAKEAVRRGAGEILLTSMDSDGE 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD  L K+VS+AV++PVIAS GAG  +H  + F +  A AALAA IFH KE  +  V
Sbjct: 181  KNGFDCRLTKLVSEAVSVPVIASGGAGRADHMYDAFAEGRADAALAASIFHYKETSVKEV 240

Query: 1746 KEHLVDAGVEVR 1781
            K +L + GV VR
Sbjct: 241  KAYLKERGVNVR 252

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>Q8YT31:HIS6_ANASP Imidazole glycerol phosphate synthase subunit hisF - Anabaena sp.|
            (strain PCC 7120)
          Length = 259

 Score =  153 bits (387), Expect = 2e-36
 Identities = 107/313 (34%), Positives = 162/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L+KR++ CLDV++       V KG  +         ++++ G PVELA  Y   GADE+ 
Sbjct: 2    LSKRILPCLDVKAGR-----VVKGVNF--------VDLKDAGDPVELAKVYNDAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT           +++V+   +E+VF+PLTVGGGI+           SLE      R
Sbjct: 49   FLDITATHE---DRDTIIDVVYRTAEQVFIPLTVGGGIQ-----------SLENVKALLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S AV   E             +++ S  +GNQ +VV+ID RR         
Sbjct: 95   AGADKVSINSAAVRDPEL------------IDRASDHFGNQCIVVAIDARR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                 +V    P  + Y      V GGR++  + A   AK VE+ GAGE+L+  +D DG 
Sbjct: 134  -----RVDPSNPGWDVY------VRGGRENTGLDALSWAKEVEKRGAGELLVTSMDADGT 182

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI+L + ++++V IPV+AS GAG  EH      +  A AAL A + H  ++ +  +
Sbjct: 183  QAGYDIELTRAIAESVEIPVVASGGAGNCEHIYTALTEGKAEAALLASLLHYGQLSVAEI 242

Query: 1746 KEHLVDAGVEVRM 1784
            K +L ++ V VR+
Sbjct: 243  KNYLHESQVPVRL 255

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>Q5MZ63:HIS5_SYNP6 Imidazole glycerol phosphate synthase subunit hisH - Synechococcus|
           sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)
           (Anacystis nidulans)
          Length = 217

 Score =  153 bits (387), Expect = 2e-36
 Identities = 88/204 (43%), Positives = 124/204 (60%), Gaps = 4/204 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DY  GN+ S    +   G N      P  ILAAD ++ PGVGAF  AMD L    +
Sbjct: 7   IAVVDYDMGNLHSACKGLEAAGANPIVTADPATILAADGVLLPGVGAFDPAMDHLRDRQL 66

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + L +     +PFLGICLGLQLLF++SEE G  +GLG++PG V+RF S  GL++PH+GW
Sbjct: 67  IEPLHQAATSGKPFLGICLGLQLLFEASEE-GQSAGLGILPGRVQRFRSEPGLVIPHMGW 125

Query: 558 NALQITK-DTQLLQ--GADGQHVYFVHSYHALPSDANKDWISLTCNYG-ESFISSISMGN 725
           N LQ+ + D  L Q  GAD    YFVH+Y+ +PS+      + T  +G +   ++I+   
Sbjct: 126 NQLQLQQPDCPLWQNLGAD-PWFYFVHTYYVVPSEPT--LTAATVQHGSQPVTAAIARDR 182

Query: 726 IQAVQFHPEKSGATGLNIFENFLS 797
           + AVQFHPEKS   GL +  NF++
Sbjct: 183 LWAVQFHPEKSAKAGLQLLANFVT 206

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>Q8DTR1:HIS5_STRMU Imidazole glycerol phosphate synthase subunit hisH - Streptococcus|
           mutans
          Length = 201

 Score =  153 bits (387), Expect = 2e-36
 Identities = 78/199 (39%), Positives = 113/199 (56%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DY AGN  +V  A+  LG        P+ I+AA  L+ PGVGAF +AM  L + G+
Sbjct: 2   IIVIDYDAGNTANVLRALDKLGVKAELSADPQKIVAASGLILPGVGAFPAAMAELEKRGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              ++E +    P LGICLG+QLL +   E+   +G G I G+ +   +  G  VPH+GW
Sbjct: 62  VAVIKEAVAKGIPLLGICLGMQLLVEKGLEHCETAGFGFISGICQEISAKAGFPVPHMGW 121

Query: 558 NALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQAV 737
           N LQ+ + + L  G  GQ VYFVHSY    +D  +++I +T +Y     + I   N+   
Sbjct: 122 NDLQVKQKSALTAGLQGQAVYFVHSYF---TDVPQEYIDVTVDYSIEVPAMIHKDNVYGA 178

Query: 738 QFHPEKSGATGLNIFENFL 794
           QFHPEKSG  GL I + F+
Sbjct: 179 QFHPEKSGDVGLGILKKFV 197

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>P61779:HIS5_DESVH Imidazole glycerol phosphate synthase subunit hisH - Desulfovibrio|
           vulgaris (strain Hildenborough / ATCC 29579 / NCIMB
           8303)
          Length = 213

 Score =  153 bits (387), Expect = 2e-36
 Identities = 85/205 (41%), Positives = 117/205 (57%), Gaps = 7/205 (3%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + +LDY AGN  SVR A+ HLG        PE I  A  ++FPGVGA G AM+ L  TG+
Sbjct: 2   LAILDYKAGNQTSVRRALDHLGIPCVITADPEVIQGAAGVIFPGVGAAGQAMNELVTTGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF------DSSEGLI 539
            + LR  ++  RP LGIC+G Q++ D S+EN     LG+IPG  R F      +    + 
Sbjct: 62  DEVLRRQVQAGRPLLGICVGCQIMLDYSQEN-DTKALGIIPGECRLFNPAWTDEDGAPIR 120

Query: 540 VPHIGWNALQITKDTQLLQGADGQ-HVYFVHSYHALPSDANKDWISLTCNYGESFISSIS 716
           VPH+GWN +   +  +LL+G + +   YFVHSY+  P +   +++  TC YG  F +   
Sbjct: 121 VPHMGWNHIVQRRPCELLKGIEPEAEFYFVHSYYPAPPE---EYVIATCTYGAEFCAIHG 177

Query: 717 MGNIQAVQFHPEKSGATGLNIFENF 791
              + AVQFHPEKSG  GL +  NF
Sbjct: 178 GPGLWAVQFHPEKSGRPGLRLLANF 202

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>Q3SEU8:HIS6_THIDA Imidazole glycerol phosphate synthase subunit hisF - Thiobacillus|
            denitrificans (strain ATCC 25259)
          Length = 251

 Score =  153 bits (386), Expect = 3e-36
 Identities = 108/313 (34%), Positives = 160/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV    NG +V  KG  +         E+++ G PVE+A  Y   GADE++
Sbjct: 2    LAKRIIPCLDVT---NGRVV--KGVNF--------VELKDAGDPVEIARGYNEAGADELT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    DL +L ++   + +VF+PLTVGGG+R   D                 
Sbjct: 49   FLDITA--SSDNRDL-ILHIVEAVASEVFIPLTVGGGVRAVAD-----------VQRLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV            T    ++  +  YG+Q +VV+ID +RV        
Sbjct: 95   AGADKVSINTSAV------------TNPQLVKDAADRYGSQCIVVAIDAKRV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         G+ +  +     GGR +  + A E AK +E LGAGE+LL  +D DG 
Sbjct: 135  -------------GDHWEVF---THGGRTATGLDAVEWAKKMESLGAGELLLTSMDRDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD++L + +SDAV +P++AS G G ++H  +   +  A A LAA IFH  E  +   
Sbjct: 179  KTGFDLELTRAISDAVDVPIVASGGVGTLQHMVDGVREGRADAVLAASIFHFGEYRVDEA 238

Query: 1746 KEHLVDAGVEVRM 1784
            K ++   G+EVR+
Sbjct: 239  KAYMKRHGIEVRL 251

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>Q4J8I9:HIS6_SULAC Imidazole glycerol phosphate synthase subunit hisF - Sulfolobus|
            acidocaldarius
          Length = 249

 Score =  153 bits (386), Expect = 3e-36
 Identities = 116/312 (37%), Positives = 167/312 (53%)
 Frame = +3

Query: 849  AKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVSF 1028
            +KR+I CLDV+     D  V KG  +          + + G PVELA++Y  +GADE+ F
Sbjct: 3    SKRIIPCLDVK-----DGRVVKGVNF--------LNLVDKGDPVELAARYEEEGADEIVF 49

Query: 1029 LNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRS 1208
            L+IT   A   G   M+ V++  +  + +PLTVGGGIR           SL+  S+   +
Sbjct: 50   LDIT---ATIEGRKTMMNVVKDTASVISIPLTVGGGIR-----------SLDDVSKILGN 95

Query: 1209 GADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQ 1388
            GADK+SI + AV              K  +   S  +G+QA+VV+ID +R+         
Sbjct: 96   GADKVSINTAAV------------ENKDLVSISSAEFGSQAIVVAIDVKRI--------- 134

Query: 1389 FRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQG 1568
                        G +Y  Y  T SG + +  I A   AK VE+LGAGEILL  ID DG  
Sbjct: 135  ------------GNDY--YVFTRSG-KYNTGINAISWAKEVEKLGAGEILLTSIDRDGTR 179

Query: 1569 GGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVK 1748
             G+DI++ +++S +V IP+IAS GAG ++ F  + +   A AALAAG+FH   + I+ +K
Sbjct: 180  EGYDIEITELISKSVNIPIIASGGAGKIDDFLGILKV--ADAALAAGVFHDGVIRIMDLK 237

Query: 1749 EHLVDAGVEVRM 1784
            ++L   GVEVRM
Sbjct: 238  KYLGKNGVEVRM 249

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>Q89WM4:HIS6_BRAJA Imidazole glycerol phosphate synthase subunit hisF - Bradyrhizobium|
            japonicum
          Length = 257

 Score =  153 bits (386), Expect = 3e-36
 Identities = 111/310 (35%), Positives = 155/310 (50%)
 Frame = +3

Query: 855  RVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVSFLN 1034
            RVI CLDV+     D  V KG  +         ++R+ G PVE A  Y   GADE++FL+
Sbjct: 5    RVIPCLDVK-----DGRVVKGVNF--------VDLRDAGDPVEAAIAYDAAGADELTFLD 51

Query: 1035 ITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRSGA 1214
            IT           ML+V+R  +E  F+P+TVGGG+R+  D                R+GA
Sbjct: 52   ITATHE---NRGIMLDVVRRTAEACFMPVTVGGGVREVDD-----------IKTLLRAGA 97

Query: 1215 DKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQFR 1394
            DK+SI S AV   E   +   K            +G Q VVV+ID +RV           
Sbjct: 98   DKVSINSAAVSRREFVKEAAEK------------FGEQCVVVAIDAKRV----------- 134

Query: 1395 TVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQGGG 1574
                  K P G+ +  +     GGR++  I A E A+ V  LGAGEILL  +D DG   G
Sbjct: 135  ------KRPGGDRWEIF---THGGRNATGIDAIEYAQEVVSLGAGEILLTSMDRDGTRQG 185

Query: 1575 FDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVKEH 1754
            FDI L + ++D++ +PVIAS G G ++H  +     +A+A LAA IFH  E  +   KEH
Sbjct: 186  FDIPLTRAIADSIPVPVIASGGVGNLDHLVDGIRDGHATAVLAASIFHFGEFTVREAKEH 245

Query: 1755 LVDAGVEVRM 1784
            +   G+ +R+
Sbjct: 246  MARRGLPMRL 255

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>Q9HU44:HIS61_PSEAE Imidazole glycerol phosphate synthase subunit hisF1 - Pseudomonas|
            aeruginosa
          Length = 256

 Score =  153 bits (386), Expect = 3e-36
 Identities = 112/312 (35%), Positives = 158/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG +++         +R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDV---DNGRVV--KGVKFE--------NIRDAGDPVEIARRYDEQGADEIT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D  +  V R AS+ VF+PLTVGGG+R   D                 
Sbjct: 50   FLDITA--SVDGRDTTLHTVERMASQ-VFIPLTVGGGVRSVQD-----------IRNLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AVF  E   +   +            +G+Q +VV+ID ++V        
Sbjct: 96   AGADKVSINTAAVFNPEFVGEAADR------------FGSQCIVVAIDAKKVSAP----- 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W +    GGR    + A   AK +E+LGAGEILL  +D DG 
Sbjct: 139  -------------GEAPRW-EIFTHGGRKPTGLDAVLWAKKMEDLGAGEILLTSMDQDGV 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ + + +S+AV +PVIAS G G +EH +    +  A A LAA IFH  E  +   
Sbjct: 185  KSGYDLGVTRAISEAVNVPVIASGGVGNLEHLAAGILEGKADAVLAASIFHFGEYTVPEA 244

Query: 1746 KEHLVDAGVEVR 1781
            K +L   G+ VR
Sbjct: 245  KAYLASRGIVVR 256

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>Q7M9X0:HIS5_WOLSU Imidazole glycerol phosphate synthase subunit hisH - Wolinella|
           succinogenes
          Length = 205

 Score =  153 bits (386), Expect = 3e-36
 Identities = 83/202 (41%), Positives = 126/202 (62%), Gaps = 4/202 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V +++Y  GN+ SV NA+  +G   +  + P  +L  DRL+ PGVGAFG AM+ L ++GM
Sbjct: 2   VGIVNYNIGNLASVLNALVKVGAKAQIEKEPSRLLEYDRLILPGVGAFGDAMEHLVQSGM 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSS---EGLIVPH 548
            +A+ E+ +  +P LGICLG+QLLF+ S E G  +GLG++ G +  FD +   EG  +P 
Sbjct: 62  KEAVLEFAKSGKPLLGICLGMQLLFEKSYEFGEHAGLGLLEGEIIPFDKTRMGEGYKIPQ 121

Query: 549 IGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGN 725
           +GWN     K + LL+G  +G ++Y+VHS+HA+ +   +D +  +  YG  F+S+I   N
Sbjct: 122 MGWNRFYAKKKSPLLKGLEEGFYLYYVHSFHAV-AKREEDVLGESV-YGYPFVSAIERDN 179

Query: 726 IQAVQFHPEKSGATGLNIFENF 791
           +   Q HPEKS   GL I +NF
Sbjct: 180 VAGFQPHPEKSHDVGLRILKNF 201

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>Q7VIW9:HIS5_HELHP Imidazole glycerol phosphate synthase subunit hisH - Helicobacter|
           hepaticus
          Length = 217

 Score =  153 bits (386), Expect = 3e-36
 Identities = 88/214 (41%), Positives = 123/214 (57%), Gaps = 14/214 (6%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDV----------RSPEDILAADRLVFPGVGAFGS 347
           V +++YG GN+ SV+NA   +  +  DV            PE +   D+L+ PGVGAFG+
Sbjct: 6   VGIINYGVGNLGSVQNAFAFIQTHFSDVLPHTLEIKVESHPERLQDYDKLLLPGVGAFGN 65

Query: 348 AMDVLNRTGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSS 527
           AM  L  T + +A+RE+++  +  +GICLG+QLLF+ SEE G   GLG+I G V  F+  
Sbjct: 66  AMTHLKNTHLDEAIREFVQSGKFLIGICLGMQLLFEQSEEFGNHKGLGLIEGKVVGFEHI 125

Query: 528 EGLIVPHIGWNALQIT---KDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGE 695
             L VPHIGWN+   T   K ++L +G ADG   YFVHS+H         +I   C YG 
Sbjct: 126 APLKVPHIGWNSCNFTPEGKHSKLFRGIADGSFFYFVHSFHI---QTQPQFILAQCTYGY 182

Query: 696 SFISSISMGNIQAVQFHPEKSGATGLNIFENFLS 797
            F + +   N+ A+Q HPEKS   GL +  NFL+
Sbjct: 183 PFGAIVHKDNLFAIQAHPEKSHNVGLRLLANFLT 216

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>P60667:HIS6_RHOPA Imidazole glycerol phosphate synthase subunit hisF - Rhodopseudomonas|
            palustris
          Length = 255

 Score =  152 bits (385), Expect = 4e-36
 Identities = 112/310 (36%), Positives = 152/310 (49%)
 Frame = +3

Query: 855  RVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVSFLN 1034
            RVI CLDV+     D  V KG  +         ++R+ G PVE A  Y   GADE+ FL+
Sbjct: 5    RVIPCLDVK-----DGRVVKGVNF--------VDLRDAGDPVEAAIAYDAAGADELCFLD 51

Query: 1035 ITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFRSGA 1214
            IT           ML+V+R  +E  F+P+TVGGG+R   D                RSGA
Sbjct: 52   ITATHE---NRGIMLDVVRRTAEACFMPVTVGGGVRTVDD-----------IKTLLRSGA 97

Query: 1215 DKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEVQFR 1394
            DK+SI S AV   E   +   K            +G+Q +VV+ID +RV  +   E+   
Sbjct: 98   DKVSINSAAVARREFVKEAAEK------------FGDQCIVVAIDAKRVPGRDRWEI--- 142

Query: 1395 TVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQGGG 1574
                                  GGR    I A E A+ V  LGAGEILL  +D DG   G
Sbjct: 143  -------------------FTHGGRKGTGIDAIEFAQEVVSLGAGEILLTSMDRDGTKSG 183

Query: 1575 FDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAVKEH 1754
            FDI L + ++D+V +PVIAS G G ++H  +   + +A+A LAA IFH  E  I   K+H
Sbjct: 184  FDIPLTRAIADSVGVPVIASGGVGNLDHLVDGIREGHATAVLAASIFHFGEYTIRQAKDH 243

Query: 1755 LVDAGVEVRM 1784
            +V AG+ +R+
Sbjct: 244  MVQAGLPMRL 253

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>Q8G6F7:HIS6_BIFLO Imidazole glycerol phosphate synthase subunit hisF - Bifidobacterium|
            longum
          Length = 256

 Score =  152 bits (385), Expect = 4e-36
 Identities = 111/314 (35%), Positives = 158/314 (50%), Gaps = 2/314 (0%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LA RVI CLDV   D G +V  KG  ++         +++ G PVELA++YY   ADE++
Sbjct: 3    LAVRVIPCLDV---DAGRVV--KGVHFE--------NLKDAGDPVELAAEYYRQRADEIT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL++T   +       M++V+   +E+VF+P+TVGGG+R   D                R
Sbjct: 50   FLDVTASSSHRN---TMIDVVSRTAEQVFIPMTVGGGVRTPED-----------VDSLLR 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+ + + A+               S + +++  +GNQ +V+S+D RR         
Sbjct: 96   CGADKVGVNTAAI------------NDPSLISRVADRFGNQVLVLSVDARR--------- 134

Query: 1386 QFRTVKVSSKGPLGEEY--AWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCD 1559
                         GE++  + ++ T  GGR S  I A    K  E+LGAGEILLN +D D
Sbjct: 135  -----------EKGEQHTQSGFEVTTMGGRKSTGIDAIWWVKRAEQLGAGEILLNSMDAD 183

Query: 1560 GQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPIL 1739
            G   GFD+++I+ V   V IP+IAS GAG VE F    E   A A LAA +FH   + I 
Sbjct: 184  GTKEGFDLEMIRAVRKEVKIPIIASGGAGKVEDFPPAIE-AGADAVLAASVFHYGILTIA 242

Query: 1740 AVKEHLVDAGVEVR 1781
             VK  L   G  VR
Sbjct: 243  DVKAELKKHGYTVR 256

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>Q5P795:HIS6_AZOSE Imidazole glycerol phosphate synthase subunit hisF - Azoarcus sp.|
            (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 252

 Score =  152 bits (385), Expect = 4e-36
 Identities = 111/313 (35%), Positives = 159/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV +       V KG  +         E+R+ G PVE+A +Y   GADE++
Sbjct: 2    LAKRIIPCLDVNAGR-----VVKGVNF--------VELRDAGDPVEIARRYDEQGADEIT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    D+ +L V+   +E+VF+PLTVGGG+R           ++E       
Sbjct: 49   FLDITA--SSDARDI-ILHVVEQVAEQVFIPLTVGGGVR-----------TVEDVRRLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV   +   +   K G            +Q +VV+ID ++    +P   
Sbjct: 95   AGADKVSINTAAVNNPQVVAEAAGKVG------------SQCIVVAIDAKQT---APGR- 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               +Q    GGR++  + A E A+ V  LGAGEILL  +D DG 
Sbjct: 139  -------------------WQVFTHGGRNNTGLDAVEWAQKVAALGAGEILLTSMDRDGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + V+DAV IPVIAS G G +EH +E   +  A A LAA IFH  +  +   
Sbjct: 180  KIGFDLGLTRAVADAVPIPVIASGGVGTLEHLAEGVSEGRADAVLAASIFHFGQHTVREA 239

Query: 1746 KEHLVDAGVEVRM 1784
            KE +   G+EVR+
Sbjct: 240  KELMRSRGIEVRL 252

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>P64362:HIS6_STAAN Imidazole glycerol phosphate synthase subunit hisF - Staphylococcus|
            aureus (strain N315)
          Length = 252

 Score =  152 bits (384), Expect = 5e-36
 Identities = 107/312 (34%), Positives = 157/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+     D  V KG Q+        K +R++G PV+LA  Y   GADE+ 
Sbjct: 2    IKKRIIPCLDVK-----DGRVVKGIQF--------KGLRDIGNPVDLAIYYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   MLEV+   + ++F+PLTVGGGI+           SL+  ++   
Sbjct: 49   FLDISKTEE---GHSLMLEVIEQTASRLFIPLTVGGGIQ-----------SLDDITQLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ S A+                 ++Q S  +G Q + ++ID            
Sbjct: 95   HGADKVSLNSSAL------------KNPQLIKQASDKFGRQCICIAID------------ 130

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                   S   P  E  A Y CT  GG+    I  Y+  + VE+LGAGE+L+  +  DG 
Sbjct: 131  -------SYYDP--ERKAHYCCT-HGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGM 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI+ +  +   V IP+IAS G G  +HF E+F +T+ SA LAA I H +E  + ++
Sbjct: 181  KQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFNQTDVSAGLAASILHDRETTVQSI 240

Query: 1746 KEHLVDAGVEVR 1781
            KE +   G+ VR
Sbjct: 241  KEVIRQGGIAVR 252

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>P64361:HIS6_STAAM Imidazole glycerol phosphate synthase subunit hisF - Staphylococcus|
            aureus (strain Mu50 / ATCC 700699)
          Length = 252

 Score =  152 bits (384), Expect = 5e-36
 Identities = 107/312 (34%), Positives = 157/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+     D  V KG Q+        K +R++G PV+LA  Y   GADE+ 
Sbjct: 2    IKKRIIPCLDVK-----DGRVVKGIQF--------KGLRDIGNPVDLAIYYNEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   MLEV+   + ++F+PLTVGGGI+           SL+  ++   
Sbjct: 49   FLDISKTEE---GHSLMLEVIEQTASRLFIPLTVGGGIQ-----------SLDDITQLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ S A+                 ++Q S  +G Q + ++ID            
Sbjct: 95   HGADKVSLNSSAL------------KNPQLIKQASDKFGRQCICIAID------------ 130

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                   S   P  E  A Y CT  GG+    I  Y+  + VE+LGAGE+L+  +  DG 
Sbjct: 131  -------SYYDP--ERKAHYCCT-HGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGM 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI+ +  +   V IP+IAS G G  +HF E+F +T+ SA LAA I H +E  + ++
Sbjct: 181  KQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFNQTDVSAGLAASILHDRETTVQSI 240

Query: 1746 KEHLVDAGVEVR 1781
            KE +   G+ VR
Sbjct: 241  KEVIRQGGIAVR 252

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>Q46WL8:HIS6_RALEJ Imidazole glycerol phosphate synthase subunit hisF - Ralstonia|
            eutropha (strain JMP134) (Alcaligenes eutrophus)
          Length = 256

 Score =  152 bits (384), Expect = 5e-36
 Identities = 114/313 (36%), Positives = 159/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV    NG +V  KG  +         E+R+ G PVE+A +Y   GADE++
Sbjct: 2    LAKRIIPCLDVT---NGRVV--KGVNF--------VELRDAGDPVEIARRYDEQGADEIT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   +L ++   + +VF+PLTVGGG+R           ++E       
Sbjct: 49   FLDIT---ATSDGRDLILHIIEAVASQVFIPLTVGGGVR-----------AVEDVRRLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKIS+ S A+   +        TGK         YG+Q +VV+ID +R         
Sbjct: 95   AGADKISVNSSAIANPQLVSDA---TGK---------YGSQCIVVAIDAKR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                    S  P GE   W   T  GGR +  + A E AK +   GAGEILL  +D DG 
Sbjct: 134  --------SSAP-GEPPRWEVFT-HGGRKATGLDAVEWAKEMAARGAGEILLTSMDRDGT 183

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD++L + VSDAV +PVIAS G G ++  ++     +A A LAA IFH  +  +   
Sbjct: 184  KSGFDLELTRAVSDAVPVPVIASGGVGGLQDLADGIRLGHADAVLAASIFHYGQHTVGEA 243

Query: 1746 KEHLVDAGVEVRM 1784
            K  +   G+ VR+
Sbjct: 244  KAFMAREGIPVRI 256

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>Q845U7:HIS6_BURCE Imidazole glycerol phosphate synthase subunit hisF - Burkholderia|
            cepacia (Pseudomonas cepacia)
          Length = 257

 Score =  152 bits (384), Expect = 5e-36
 Identities = 112/313 (35%), Positives = 157/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV +       V KG  +         E+R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDVTAGR-----VVKGVNF--------VELRDAGDPVEIARRYDEQGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT        DL +L ++   + +VF+PLTVGGG+R           ++E       
Sbjct: 50   FLDITA--TSDQRDL-ILPIIEAVASQVFIPLTVGGGVR-----------AVEDVRRLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV   +       K            YG+Q +VV+ID +RV   S D  
Sbjct: 96   AGADKVSMNSSAVANPQLVRDAADK------------YGSQCIVVAIDAKRV---SAD-- 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W   T  GGR    + A E A+ + E GAGEILL  +D DG 
Sbjct: 139  -------------GEAPRWEVFT-HGGRKGTGLDAIEWARKMAEFGAGEILLTSMDRDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + VSDAV +PVIAS G G+++  ++  +   A A LAA IFH  E  +   
Sbjct: 185  KSGFDLALTRGVSDAVPVPVIASGGVGSLQDLADGIKDGRADAVLAASIFHYGEHTVGEA 244

Query: 1746 KEHLVDAGVEVRM 1784
            K  + + G+ VR+
Sbjct: 245  KRFMAEQGIPVRL 257

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>Q8DIP5:HIS5_SYNEL Imidazole glycerol phosphate synthase subunit hisH - Synechococcus|
           elongatus (Thermosynechococcus elongatus)
          Length = 209

 Score =  151 bits (382), Expect = 8e-36
 Identities = 86/209 (41%), Positives = 116/209 (55%), Gaps = 6/209 (2%)
 Frame = +3

Query: 189 ANTVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNR 368
           A  + ++DY  GN+ SV  A+  +G        P +I AAD +V PGVGAF  AM  L  
Sbjct: 3   APAIAIIDYDMGNLHSVSKALEVVGARPLISDRPAEIFAADAVVLPGVGAFDPAMARLQE 62

Query: 369 TGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPH 548
             +   + + I    PFLGICLGLQ+LF+ SEE G   GLG+  G V+RF S  GL +PH
Sbjct: 63  RELVPVIEQIIEQGMPFLGICLGLQVLFECSEE-GTEPGLGIFAGKVKRFQSEPGLTIPH 121

Query: 549 IGWNALQITKDTQLLQGADGQH------VYFVHSYHALPSDANKDWISLTCNYGESFISS 710
           +GWN L +      L     QH      VYFVHSY   P D +    +  C+  ++  ++
Sbjct: 122 MGWNQLTLRPSASPL----WQHLPPSPWVYFVHSYFVAPEDPSL-VAATVCHGQQTVTAA 176

Query: 711 ISMGNIQAVQFHPEKSGATGLNIFENFLS 797
           I+  N+ A QFHPEKSGA GL +  NF++
Sbjct: 177 IARNNLFACQFHPEKSGAVGLQLLRNFVA 205

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>Q7MPK8:HIS53_VIBVY Imidazole glycerol phosphate synthase subunit hisH 3 - Vibrio|
           vulnificus (strain YJ016)
          Length = 206

 Score =  151 bits (382), Expect = 8e-36
 Identities = 78/207 (37%), Positives = 126/207 (60%), Gaps = 7/207 (3%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           +T++DYG GN+++  N  + L   +       D+  A +++ PGVGAF  AM +LN +GM
Sbjct: 2   ITIVDYGLGNIKAFANLYKKLNIELVFASDVNDLANATKIILPGVGAFDHAMQMLNDSGM 61

Query: 378 ADALREYIRMDR-PFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLI----- 539
            + L E +   + P +GIC+G+Q++ DSSEE G + GLG IPG V++F      +     
Sbjct: 62  RETLDELVLEKKVPVIGICVGMQMMADSSEE-GQLKGLGWIPGTVKKFKRESQALESQYP 120

Query: 540 VPHIGWNALQITKDTQLLQGADGQHV-YFVHSYHALPSDANKDWISLTCNYGESFISSIS 716
           +PH+GWN+L+I + ++LL G D Q + YF+HSY+  P+D  K+ +  T NYG  +   ++
Sbjct: 121 LPHMGWNSLEIARTSELLLGLDEQKLFYFLHSYYYEPND--KEHVVATANYGFEYACIVN 178

Query: 717 MGNIQAVQFHPEKSGATGLNIFENFLS 797
             N+  +Q HPEKS   G+ + ++F S
Sbjct: 179 KDNVYGIQCHPEKSHHNGVALLKSFAS 205

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>Q7VDF1:HIS6_PROMA Imidazole glycerol phosphate synthase subunit hisF - Prochlorococcus|
            marinus
          Length = 257

 Score =  150 bits (380), Expect = 1e-35
 Identities = 110/312 (35%), Positives = 161/312 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A R+I CLDV    NG +V  KG  +          +R+ G PVELA +Y  +GADE+ 
Sbjct: 2    VALRLIPCLDVA---NGRVV--KGVNF--------VGLRDAGDPVELACRYSREGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I            ++E++R  +E V +P TVGGGI           SS+E  +E  R
Sbjct: 49   FLDIAASHE---ARATLVEIVRRTAESVTIPFTVGGGI-----------SSIEGITELLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKIS+ S AV                 + + +  +G+Q +VV+ID +R         
Sbjct: 95   AGADKISLNSSAV------------KDPGLVSRGACQFGSQCIVVAIDAKRRL------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                          EE + +   V+GGR +  + A   A+ V ELGAGEILL  +D DG 
Sbjct: 136  --------------EESSGWDVFVNGGRKNTGLDALSWARKVVELGAGEILLTSMDGDGT 181

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D++L K +S +V +PVIAS GAG +E   E FE  NASAAL A + H +++ I  +
Sbjct: 182  QKGYDLELTKTISQSVQVPVIASGGAGCLEDVFEAFEYGNASAALLASLLHDQDLTIEEI 241

Query: 1746 KEHLVDAGVEVR 1781
            K +L+   + +R
Sbjct: 242  KNYLLKKNLIIR 253

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>Q8XV85:HIS6_RALSO Imidazole glycerol phosphate synthase subunit hisF - Ralstonia|
            solanacearum (Pseudomonas solanacearum)
          Length = 256

 Score =  150 bits (379), Expect = 2e-35
 Identities = 113/313 (36%), Positives = 157/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV    NG +V  KG  +         E+R+ G PVE+A +Y   GADE++
Sbjct: 2    LAKRIIPCLDVT---NGRVV--KGVNF--------VELRDAGDPVEIARRYDEQGADEIT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G   +L ++   + +VF+PLTVGGG+R           +LE       
Sbjct: 49   FLDIT---ATSDGRDLILHIIEAVASQVFIPLTVGGGVR-----------ALEDVRRLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADKIS+ S AV                 +   S  +G Q +VV+ID ++V   S D  
Sbjct: 95   AGADKISMNSSAV------------ANPQLVSDASARHGAQCIVVAIDAKKV---SAD-- 137

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W   T  GGR +  + A   A+ +   GAGEILL  +D DG 
Sbjct: 138  -------------GEPPRWEVFT-HGGRKATGLDAVAWAREMARRGAGEILLTSMDRDGT 183

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD++L + VSDAV +PVIAS G G ++H ++  +  +A A LAA IFH  E  +   
Sbjct: 184  KSGFDLELTRAVSDAVPVPVIASGGVGNLQHLADGIKLGHADAVLAASIFHYGEHTVGEA 243

Query: 1746 KEHLVDAGVEVRM 1784
            K  +    + VRM
Sbjct: 244  KRFMAQQDIPVRM 256

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>Q3B2Q6:HIS6_PELLD Imidazole glycerol phosphate synthase subunit hisF - Pelodictyon|
            luteolum (strain DSM 273) (Chlorobium luteolum (strain
            DSM 273))
          Length = 251

 Score =  150 bits (379), Expect = 2e-35
 Identities = 116/313 (37%), Positives = 161/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDVR     D  V KG  ++         +R+ G  +E A  Y  + ADE+ 
Sbjct: 2    LAKRIIPCLDVR-----DGRVVKGINFE--------GLRDAGSILEQARFYNNELADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   +       + EVL+ + E VF+PLTVGGGI           +S+E A E F 
Sbjct: 49   FLDISA--SLESRRTTLEEVLKVSGE-VFIPLTVGGGI-----------NSVERAREVFL 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ + AV   E             + +I+  YG+QAVVV+ID ++V  +     
Sbjct: 95   HGADKVSVNTAAVKEPEL------------ISRIAEKYGSQAVVVAIDIKKVDGR----- 137

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               Y      G+      A E A  V+ELGAGEILL  +D DG 
Sbjct: 138  -------------------YIVHTHSGKQPTAYEALEWALKVQELGAGEILLTSMDRDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D D + ++S AV IPVIAS GAG++EH  + F K +A AALAA IFH ++  I   
Sbjct: 179  KEGYDNDSLALISTAVHIPVIASGGAGSLEHLYDGFTKGHADAALAASIFHFRQHSIREA 238

Query: 1746 KEHLVDAGVEVRM 1784
            K++L D G+ VR+
Sbjct: 239  KQYLRDRGITVRL 251

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>Q3Z7F5:HIS6_DEHE1 Imidazole glycerol phosphate synthase subunit hisF - Dehalococcoides|
            ethenogenes (strain 195)
          Length = 253

 Score =  150 bits (379), Expect = 2e-35
 Identities = 113/314 (35%), Positives = 155/314 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KRVI CLDV   +NG +V  KG        +S   +R+ G PVELA++YY +GADE+ 
Sbjct: 2    LNKRVIPCLDV---NNGRVV--KG--------TSFVNLRDAGNPVELAARYYREGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   A       M EV+   S++VF+PL VGGG+R   D            +   R
Sbjct: 49   FLDIS---ATTEERKTMAEVVEQVSKEVFIPLCVGGGLRSIAD-----------MNTLLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S AV   +   +   K            +G Q +VV+ID +R         
Sbjct: 95   AGADKVSINSAAVSDPDLISRGAEK------------FGRQCIVVAIDAKR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E + +Q     G+    + A E A   E LGAGEILL  ID DG+
Sbjct: 134  ---------------EGSGWQVYTHSGKKPAGLDAVEWAIKAEALGAGEILLTSIDADGK 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D +L + +S  + IPVIAS GAG+ E      +K  A A LAA IFH     I  V
Sbjct: 179  NTGYDNELNREISSRLNIPVIASGGAGSPEDLYNALDKGQADAVLAASIFHYGRYTIAEV 238

Query: 1746 KEHLVDAGVEVRMQ 1787
            K++L   G+ VR++
Sbjct: 239  KQYLKSKGLPVRLE 252

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>Q67KH8:HIS5_SYMTH Imidazole glycerol phosphate synthase subunit hisH -|
           Symbiobacterium thermophilum
          Length = 212

 Score =  150 bits (379), Expect = 2e-35
 Identities = 83/199 (41%), Positives = 116/199 (58%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+ SVRNA+R +GF       P  +  AD LV PGVGAFG+ M  L R G+
Sbjct: 4   IVIVDYGMGNLASVRNALRAVGFEAAVSDDPAAVAGADGLVLPGVGAFGTGMQNLARRGL 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
             A+R+     RP LGICLG+QLL    +E GP  GLG++ G V R    +GL +P IGW
Sbjct: 64  DQAVRQAAAAGRPVLGICLGMQLLLAEGDEGGPRPGLGLLEGRVARL--PDGLPLPQIGW 121

Query: 558 NALQITKDTQLLQGADGQH-VYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N ++  +D  L  G       YF H+Y A+  +     ++LT +YG ++ S +  GN+  
Sbjct: 122 NLVEPQRDHPLFAGLPTPFWAYFDHAY-AVEGEPPSTALALT-DYGRTYPSVVGRGNLLG 179

Query: 735 VQFHPEKSGATGLNIFENF 791
           +QFHPEKS   GL +  N+
Sbjct: 180 IQFHPEKSSRAGLRMLANW 198

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>Q5P793:HIS5_AZOSE Imidazole glycerol phosphate synthase subunit hisH - Azoarcus sp.|
           (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 212

 Score =  150 bits (379), Expect = 2e-35
 Identities = 88/210 (41%), Positives = 122/210 (58%), Gaps = 10/210 (4%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHL--GFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRT 371
           V ++DYG GN+RSV  AI H+  G  +     P  + AA R+VFPG GA    M  L+  
Sbjct: 4   VAIIDYGMGNLRSVAKAIEHVAPGKRVAVTSDPAVVAAAARVVFPGQGAMPDCMRELDLR 63

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSE------- 530
           G+ + ++      +PFLGIC+G Q+LF+ SEE G V GLG++PG V RF  ++       
Sbjct: 64  GLREVVKT-AAASKPFLGICIGQQMLFEHSEE-GNVPGLGILPGGVVRFPDAKMVAADGS 121

Query: 531 GLIVPHIGWNALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFIS 707
            L VPH+GWN +   K   + +G  D +  YFVHSY   P+DA    ++   +YG  F S
Sbjct: 122 RLKVPHMGWNEVCQRKPHPMWEGIPDNERFYFVHSYFVAPADAAL--VAAESDYGTRFTS 179

Query: 708 SISMGNIQAVQFHPEKSGATGLNIFENFLS 797
           +++  NI AVQFHPEKS   GL +  NF+S
Sbjct: 180 AVARANIFAVQFHPEKSAQAGLKMLANFIS 209

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>Q4FPZ3:HIS6_PSYAR Imidazole glycerol phosphate synthase subunit hisF - Psychrobacter|
            arcticum
          Length = 260

 Score =  150 bits (378), Expect = 2e-35
 Identities = 109/313 (34%), Positives = 155/313 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG Q+         ++++ G PVE+A +Y   GADE++
Sbjct: 2    LAKRIIPCLDV---DNGRVV--KGVQF--------VDIKDAGDPVEVAKRYNEQGADEIT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT        D     V R A E VFVPLTVGGG+R   D                 
Sbjct: 49   FLDITA--TSDERDTTYHTVERMA-ETVFVPLTVGGGVRKIAD-----------IRNLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK++I S AVF  E   +   K            +GNQ +VV+ID +RV     D +
Sbjct: 95   AGADKVAINSAAVFTPEFVGEAAQK------------FGNQCIVVAIDAKRVADIEVDGI 142

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               ++    GGR    I A   A+ + ELGAGE+L+  +D DG 
Sbjct: 143  IMPR---------------WEIFTHGGRKPTGIDAVAWARKMAELGAGELLVTSMDGDGT 187

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L+K ++  V +PVIAS G G ++H +E   +    A LAA IFH  E  +   
Sbjct: 188  KKGYDLALMKQITSRVNVPVIASGGVGNLQHLAEGVLEGGVDAVLAASIFHFGEYTVQEA 247

Query: 1746 KEHLVDAGVEVRM 1784
            K ++   G+++R+
Sbjct: 248  KAYMAAQGIQMRL 260

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>Q3ZY29:HIS6_DEHSC Imidazole glycerol phosphate synthase subunit hisF - Dehalococcoides|
            sp. (strain CBDB1)
          Length = 253

 Score =  150 bits (378), Expect = 2e-35
 Identities = 114/314 (36%), Positives = 157/314 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KRVI CLDV   +NG +V  KG        +S   +R+ G PVELA++YY +GADE+ 
Sbjct: 2    LNKRVIPCLDV---NNGRVV--KG--------TSFVNLRDAGDPVELAARYYREGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   A       M EV+   S++VF+PL VGGG+R   D            +   R
Sbjct: 49   FLDIS---ATTEERKTMAEVVEKVSKEVFIPLCVGGGLRSIAD-----------MTTLLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV   +   +   K            +G Q +VV+ID +R         
Sbjct: 95   AGADKVSVNSAAVSDPDLISRGAEK------------FGRQCIVVAIDAKR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                          E  +W   T SG + +  + A E A   E+LGAGEILL  ID DG+
Sbjct: 134  --------------EGNSWQVYTHSGKKPTG-LDAVEWAMKAEQLGAGEILLTSIDADGK 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D +L + V   + IPVIAS GAG+ E      +K  A A LAA IFH     I  V
Sbjct: 179  NTGYDNELNREVGSRLNIPVIASGGAGSPEDLYNALDKGQADAVLAASIFHYGRYSIAEV 238

Query: 1746 KEHLVDAGVEVRMQ 1787
            K++L   G+ VR++
Sbjct: 239  KKYLKSKGLPVRLE 252

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>Q7W2X9:HIS6_BORPA Imidazole glycerol phosphate synthase subunit hisF - Bordetella|
            parapertussis
          Length = 269

 Score =  149 bits (377), Expect = 3e-35
 Identities = 108/316 (34%), Positives = 156/316 (49%)
 Frame = +3

Query: 837  ASKLAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGAD 1016
            AS L +R+I CLDV +       V KG  +          + + G PVE+A +Y   GAD
Sbjct: 11   ASTLTRRIIPCLDVTAGR-----VVKGVNF--------VNLTDAGDPVEIARRYNEQGAD 57

Query: 1017 EVSFLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASE 1196
            E++FL+IT   A   G   +L ++   + +VF+PLTVGGG+R  +D              
Sbjct: 58   ELTFLDIT---ATSDGHDLILPIIEQVASQVFIPLTVGGGVRQVSD-----------VQR 103

Query: 1197 YFRSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSP 1376
               +GADKISI S AV   E             +   +  +G+Q +VV+ID RR   +  
Sbjct: 104  LLNAGADKISINSAAVANPEL------------VRAAADYHGSQCIVVAIDARRSSAE-- 149

Query: 1377 DEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDC 1556
                            GE   W   T  GGR +  + A   A+ +   GAGEILL  +D 
Sbjct: 150  ----------------GEPARWEVFT-HGGRKATGLDAVAWARRMAAYGAGEILLTSMDR 192

Query: 1557 DGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPI 1736
            DG   GFD++L + VSDAV +PVIAS G G ++H ++      ASA LAA IFH  +  +
Sbjct: 193  DGTKSGFDLELTRAVSDAVPVPVIASGGVGNLQHLADGVTTGRASAVLAASIFHFGQHTV 252

Query: 1737 LAVKEHLVDAGVEVRM 1784
               K+++ + G+ VR+
Sbjct: 253  RECKQYMAERGIAVRL 268

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>Q4A049:HIS6_STAS1 Imidazole glycerol phosphate synthase subunit hisF - Staphylococcus|
            saprophyticus subsp. saprophyticus (strain ATCC 15305 /
            DSM 20229)
          Length = 252

 Score =  149 bits (376), Expect = 4e-35
 Identities = 103/312 (33%), Positives = 151/312 (48%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            + KR+I CLDV+     D  V KG Q+        K +R++G PV+ A  Y   GADE+ 
Sbjct: 2    IKKRIIPCLDVK-----DGRVVKGIQF--------KGLRDIGNPVDFALYYNEQGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   A   G   +L+V+   +EK+F+PLTVGGGI           S+++  S+   
Sbjct: 49   FLDISRTEA---GHDLVLDVISETAEKLFIPLTVGGGI-----------STIDDISQLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ S A+               S +++ S  +G Q + ++ID            
Sbjct: 95   HGADKVSLNSSAL------------KNPSFIKEASEKFGRQCICIAIDSN---------- 132

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E   Y C   GG+       Y+  + VE LGAGE+L+  +  DG 
Sbjct: 133  ------------YDSELNDYFCYTHGGKQRTDKRVYDWVQEVEALGAGELLITSMTHDGM 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+  +  +   V IPVIAS G G  EHF ++F++TN SA LAA I H KE  +  +
Sbjct: 181  KQGFDVSHLHEIEKLVNIPVIASGGGGNPEHFVDLFKETNVSAGLAASILHDKETTVNQI 240

Query: 1746 KEHLVDAGVEVR 1781
            K  +   G+ VR
Sbjct: 241  KSSMKRGGIPVR 252

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>Q3AD48:HIS6_CARHZ Imidazole glycerol phosphate synthase subunit hisF - Carboxydothermus|
            hydrogenoformans (strain Z-2901 / DSM 6008)
          Length = 259

 Score =  149 bits (376), Expect = 4e-35
 Identities = 111/313 (35%), Positives = 154/313 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L  R+I CLDV         V KG  +          + + G PVELA+ Y  +GADEV 
Sbjct: 2    LTVRIIPCLDVNKGR-----VVKGVNF--------LNLVDAGDPVELAAFYDREGADEVV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +F  G   M+EV +  +  + +P T+GGGIR+  D                 
Sbjct: 49   FLDITA--SFE-GRQTMVEVAKRTATTLSIPFTIGGGIRNIDD-----------IRALLA 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            SGADK+SI S AV   E   +  +K            +G+Q +VV+ID +R         
Sbjct: 95   SGADKVSINSAAVKNPELVREAALK------------FGSQCIVVAIDAKR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                          ++   ++  + GGR    I A E AK VE LGAGEILL  +D DG 
Sbjct: 134  --------------KKDGGFEVYIHGGRTPTGIDAVEWAKEVERLGAGEILLTSMDRDGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D++L + ++DAV IPVIAS G G + HF E     +ASA LAA +FH  +  I  V
Sbjct: 180  KDGYDLELTREIADAVKIPVIASGGVGELSHFYEGVVLGHASALLAASVFHFGKFTIKEV 239

Query: 1746 KEHLVDAGVEVRM 1784
            K +L + G+ VR+
Sbjct: 240  KRYLKERGIPVRL 252

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>Q7VSY6:HIS6_BORPE Imidazole glycerol phosphate synthase subunit hisF - Bordetella|
            pertussis
          Length = 269

 Score =  149 bits (376), Expect = 4e-35
 Identities = 108/316 (34%), Positives = 156/316 (49%)
 Frame = +3

Query: 837  ASKLAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGAD 1016
            AS L +R+I CLDV +       V KG  +          + + G PVE+A +Y   GAD
Sbjct: 11   ASTLTRRIIPCLDVTAGR-----VVKGVNF--------VNLTDAGDPVEIARRYNEQGAD 57

Query: 1017 EVSFLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASE 1196
            E++FL+IT   A   G   +L ++   + +VF+PLTVGGG+R  +D              
Sbjct: 58   ELTFLDIT---ATSDGRDLILPIIEQVASQVFIPLTVGGGVRQVSD-----------VQR 103

Query: 1197 YFRSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSP 1376
               +GADKISI S AV   E             +   +  +G+Q +VV+ID RR   +  
Sbjct: 104  LLNAGADKISINSAAVANPEL------------VRAAADYHGSQCIVVAIDARRSSAE-- 149

Query: 1377 DEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDC 1556
                            GE   W   T  GGR +  + A   A+ +   GAGEILL  +D 
Sbjct: 150  ----------------GEPARWEVFT-HGGRKATGLDAVAWARRMAAYGAGEILLTSMDR 192

Query: 1557 DGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPI 1736
            DG   GFD++L + VSDAV +PVIAS G G ++H ++      ASA LAA IFH  +  +
Sbjct: 193  DGTKSGFDLELTRAVSDAVPVPVIASGGVGNLQHLADGVTTGRASAVLAASIFHFGQHTV 252

Query: 1737 LAVKEHLVDAGVEVRM 1784
               K+++ + G+ VR+
Sbjct: 253  RECKQYMAERGIAVRL 268

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>Q7WDX9:HIS6_BORBR Imidazole glycerol phosphate synthase subunit hisF - Bordetella|
            bronchiseptica (Alcaligenes bronchisepticus)
          Length = 269

 Score =  149 bits (376), Expect = 4e-35
 Identities = 108/316 (34%), Positives = 156/316 (49%)
 Frame = +3

Query: 837  ASKLAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGAD 1016
            AS L +R+I CLDV +       V KG  +          + + G PVE+A +Y   GAD
Sbjct: 11   ASTLTRRIIPCLDVTAGR-----VVKGVNF--------VNLTDAGDPVEIARRYNEQGAD 57

Query: 1017 EVSFLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASE 1196
            E++FL+IT   A   G   +L ++   + +VF+PLTVGGG+R  +D              
Sbjct: 58   ELTFLDIT---ATSDGRDLILPIIEQVASQVFIPLTVGGGVRQVSD-----------VQR 103

Query: 1197 YFRSGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSP 1376
               +GADKISI S AV   E             +   +  +G+Q +VV+ID RR   +  
Sbjct: 104  LLNAGADKISINSAAVANPEL------------VRAAADYHGSQCIVVAIDARRSSAE-- 149

Query: 1377 DEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDC 1556
                            GE   W   T  GGR +  + A   A+ +   GAGEILL  +D 
Sbjct: 150  ----------------GEPARWEVFT-HGGRKATGLDAVAWARRMAAYGAGEILLTSMDR 192

Query: 1557 DGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPI 1736
            DG   GFD++L + VSDAV +PVIAS G G ++H ++      ASA LAA IFH  +  +
Sbjct: 193  DGTKSGFDLELTRAVSDAVPVPVIASGGVGNLQHLADGVTTGRASAVLAASIFHFGQHTV 252

Query: 1737 LAVKEHLVDAGVEVRM 1784
               K+++ + G+ VR+
Sbjct: 253  RECKQYMAERGIAVRL 268

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>Q5WDI0:HIS5_BACSK Imidazole glycerol phosphate synthase subunit hisH - Bacillus|
           clausii (strain KSM-K16)
          Length = 207

 Score =  149 bits (376), Expect = 4e-35
 Identities = 78/202 (38%), Positives = 117/202 (57%), Gaps = 4/202 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+ SV  A+  L          E++  A  L+ PGVGAF  AM++L +T +
Sbjct: 2   IGIIDYGMGNLHSVSKALERLAIPYFISSDGEELAKAKALILPGVGAFPDAMNILTQTNV 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFD--SSEG--LIVP 545
              L  ++  ++P LGICLG+QLLF+SS E+ P +GLG +PG V RF   ++EG    VP
Sbjct: 62  QPFLDNWVAENKPLLGICLGMQLLFESSNEHQPTAGLGYLPGRVERFSGTTAEGHAYKVP 121

Query: 546 HIGWNALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGN 725
           H+GWN L+  + T L +G    +VYFVHSY         D +  + +Y +S  + +  G 
Sbjct: 122 HMGWNKLEFHRPTPLTEGVPDGYVYFVHSYVV---RTETDIVVASSDYYQSVPAIVQKGQ 178

Query: 726 IQAVQFHPEKSGATGLNIFENF 791
           +  +QFHPEKS   G+ + + F
Sbjct: 179 VYGMQFHPEKSSTVGMALLKRF 200

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>Q6HLE5:HIS5_BACHK Imidazole glycerol phosphate synthase subunit hisH - Bacillus|
           thuringiensis subsp. konkukian
          Length = 209

 Score =  149 bits (376), Expect = 4e-35
 Identities = 78/199 (39%), Positives = 115/199 (57%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+RSV  A++++G         E+I  +D ++ PGVGAF  AMD+L    +
Sbjct: 2   IAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              L+E     +P LGICLG+QLLF+ SEE    +GL ++PGV+R+        +PH+GW
Sbjct: 62  VRVLQEIGCSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKL--KVPYKIPHMGW 119

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L+   +  L  G  D   VY+VHSY+A   D   + +    +YG      ++ GNI  
Sbjct: 120 NELKKEGEIALWNGVEDSSFVYYVHSYYA---DCPNEIVYGISDYGVKVPGFVAKGNIYG 176

Query: 735 VQFHPEKSGATGLNIFENF 791
            QFHPEKSG  G+ + +NF
Sbjct: 177 AQFHPEKSGDIGMQMLKNF 195

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>Q46GY9:HIS6_PROMT Imidazole glycerol phosphate synthase subunit hisF - Prochlorococcus|
            marinus (strain NATL2A)
          Length = 256

 Score =  149 bits (375), Expect = 5e-35
 Identities = 110/312 (35%), Positives = 161/312 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A R+I CLDV    NG +V  KG  +          +R+ G PVEL  +Y   GADE+ 
Sbjct: 2    VALRLIPCLDV---SNGRVV--KGVNF--------VGLRDAGDPVELGCRYSKAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       +++++R  SE V +P TVGGGI           SSL   +E  R
Sbjct: 49   FLDIT---ATYEKRSTLVDMVRRTSESVTIPFTVGGGI-----------SSLNGINELLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV               S + + +  +G+Q +VV+ID ++         
Sbjct: 95   AGADKVSLNSSAV------------KDPSLISKGANRFGSQCIVVAIDAKK--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                  + +K         +   VSGGR++  + A E A+ V E+GAGEILL  +D DG 
Sbjct: 134  ---NKNIPNK---------WDVYVSGGRNNTGLDAIEWAEKVFEMGAGEILLTSMDGDGT 181

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI+L K ++D V IPVIAS GAG + H  E F    +SAAL A + H  ++ I  +
Sbjct: 182  QNGYDIELTKCIADKVPIPVIASGGAGCLRHIKEAFTLGKSSAALLASLLHDGQLTIREI 241

Query: 1746 KEHLVDAGVEVR 1781
            KE+L+   + +R
Sbjct: 242  KEYLIKENLPIR 253

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>Q2YAV0:HIS6_NITMU Imidazole glycerol phosphate synthase subunit hisF - Nitrosospira|
            multiformis (strain ATCC 25196 / NCIMB 11849)
          Length = 252

 Score =  149 bits (375), Expect = 5e-35
 Identities = 107/313 (34%), Positives = 159/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV    NG +V  KG ++          +R+ G P+E+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDVT---NGRVV--KGVKF--------VSLRDAGDPIEIARRYDDQGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   +    DL +L ++   + +VF+PLTVGGG+R   D                 
Sbjct: 50   FLDITA--SSDDRDL-ILHIIEEVAAQVFIPLTVGGGVRKVED-----------VRRLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + A+   +       +            YG+Q +VV+ID +R         
Sbjct: 96   AGADKVSINTSAIQNPQLVADAAGR------------YGSQCIVVAIDAKR--------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                   + +G        ++    GGR    + A E AK ++ LGAGEILL  +D DG 
Sbjct: 135  -------AGQG--------WEVFTHGGRKPTGLDAIEWAKKMQSLGAGEILLTSMDRDGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + VSDAV +PVIAS G G ++H  +   + +A A LAA +FH  E  +   
Sbjct: 180  RDGFDLALTRAVSDAVDVPVIASGGVGNLQHLVDGVVEGHADAVLAASVFHYGEYTVRQA 239

Query: 1746 KEHLVDAGVEVRM 1784
            KE++   G+EVR+
Sbjct: 240  KEYMSQHGIEVRL 252

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>P58789:HIS5_PYRFU Imidazole glycerol phosphate synthase subunit hisH - Pyrococcus|
           furiosus
          Length = 194

 Score =  149 bits (375), Expect = 5e-35
 Identities = 86/200 (43%), Positives = 122/200 (61%), Gaps = 2/200 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++D G GN+ +V+ A++  G+   D   P +I  AD++V PGVG FG+ +D L    +
Sbjct: 4   IAIVDLGIGNLANVKKALK--GYITSD---PYEIEKADKIVLPGVGNFGAVVDKL--API 56

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            D + E I   +PFLGICLG+QLLF+ SEE+    GLG+  G V +    + +  PHIGW
Sbjct: 57  KDIIIEGINEGKPFLGICLGMQLLFEESEESPGKEGLGIFKGKVVKL---KNVRTPHIGW 113

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNY-GESFISSISMGNIQ 731
           N + I K+ +L +G  +G + YFVHSYHA+P D   D I+ T +Y    F+SS+   NI 
Sbjct: 114 NQVWIKKECKLFEGLKNGSYFYFVHSYHAVPQD--PDIIATTTDYENAEFVSSVCFENIF 171

Query: 732 AVQFHPEKSGATGLNIFENF 791
            VQFHPEKS   GL +  NF
Sbjct: 172 GVQFHPEKSSKNGLILLRNF 191

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>Q4FNT5:HIS5_PELUB Imidazole glycerol phosphate synthase subunit hisH - Pelagibacter|
           ubique
          Length = 208

 Score =  149 bits (375), Expect = 5e-35
 Identities = 82/207 (39%), Positives = 119/207 (57%), Gaps = 7/207 (3%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLG---FNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNR 368
           VT++DY +GN+ SV N+ + +     NI        I ++D++V PG G+F S +D LN 
Sbjct: 3   VTIVDYNSGNISSVINSFKEVAKDKVNIEVTSDLNKIRSSDKVVLPGQGSFKSCVDALNA 62

Query: 369 -TGMADALREY-IRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLI- 539
             G+ + L E+ +   +P LGIC+GLQ+  D   E     GLG I G V + D+      
Sbjct: 63  INGLVETLNEFTVTNKKPLLGICVGLQMFADLGYEETETKGLGWISGKVSKIDNQNNKFK 122

Query: 540 VPHIGWNALQITKDTQLLQGADGQ-HVYFVHSYHALPSDANKDWISLTCNYGESFISSIS 716
           +PHIGWN + I K++++ +G   + H+YFVHSY  +P D  K  IS T +Y  + + S+ 
Sbjct: 123 LPHIGWNEINIVKESKIFEGIKNKSHMYFVHSYEFIPDD--KSVISATTDYSSNIVCSVE 180

Query: 717 MGNIQAVQFHPEKSGATGLNIFENFLS 797
             NI   QFHPEKS   GL I ENFL+
Sbjct: 181 KENIFGTQFHPEKSDKLGLKIIENFLN 207

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>Q3ATG0:HIS6_CHLCH Imidazole glycerol phosphate synthase subunit hisF - Chlorobium|
            chlorochromatii (strain CaD3)
          Length = 251

 Score =  148 bits (374), Expect = 7e-35
 Identities = 120/312 (38%), Positives = 159/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDVR     D  V KG  ++         +R+ G  +E A  Y  + ADE+ 
Sbjct: 2    LAKRIIPCLDVR-----DGRVVKGINFE--------GLRDAGSILEQARFYNNELADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   A        LE +   SE+VF+PLTVGGGI           SS+E A E F 
Sbjct: 49   FLDIS---ASLESRRTTLEEVMKVSEEVFIPLTVGGGI-----------SSVERAREVFL 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ + AV   + YL          + +I+  YG+QAVVV+ID ++V        
Sbjct: 95   HGADKVSVNTAAV--NDPYL----------ISRIAEKYGSQAVVVAIDIKKV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         G  Y  +      G+      A E A  V+ELGAGEILL  +D DG 
Sbjct: 135  -------------GNHYMVH---THSGKQITQYEALEWALKVQELGAGEILLTSMDRDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G++ + ++M+S AV IPVIAS GAG +EH  + F K  A AALAA IFH +   I   
Sbjct: 179  KEGYENNSLRMISTAVHIPVIASGGAGNLEHLYDGFSKGCADAALAASIFHFRHYSIRQA 238

Query: 1746 KEHLVDAGVEVR 1781
            KE+L   GV VR
Sbjct: 239  KEYLHKRGVAVR 250

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>Q55805:HIS5_SYNY3 Imidazole glycerol phosphate synthase subunit hisH - Synechocystis|
           sp. (strain PCC 6803)
          Length = 210

 Score =  148 bits (374), Expect = 7e-35
 Identities = 87/201 (43%), Positives = 115/201 (57%), Gaps = 2/201 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DY  GN+ SV   +  +G N         I  A  +V PGVG+F  A+  L   G+
Sbjct: 4   IAVVDYDMGNLHSVCKGLEKVGGNPLVTDQAHVIDGATAIVLPGVGSFDPAVQHLRARGL 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + L+  I    PFLGICLG QLLFDSSEE G  +GLG+IPG V+ F S  GL +PH+GW
Sbjct: 64  EEVLKTAIAKGIPFLGICLGSQLLFDSSEE-GQETGLGIIPGQVKHFRSEPGLTIPHMGW 122

Query: 558 NALQITK-DTQLLQGADGQ-HVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           N LQ  + D  L Q    +  VYFVHSY+  P D      S T +  ++  ++I+  N+ 
Sbjct: 123 NGLQFNQPDLCLWQDLPPEPQVYFVHSYYMAPLDPQVIAAS-TTHGSQTIAAAIAKDNVM 181

Query: 732 AVQFHPEKSGATGLNIFENFL 794
           AVQFHPEKS   GL I  NF+
Sbjct: 182 AVQFHPEKSSTLGLKILANFV 202

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>Q6A7Y8:HIS6_PROAC Imidazole glycerol phosphate synthase subunit hisF -|
            Propionibacterium acnes
          Length = 251

 Score =  148 bits (373), Expect = 9e-35
 Identities = 113/312 (36%), Positives = 154/312 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A RVI CLDV+     D  V KG  +          +R+ G PVELA++Y   GADEV+
Sbjct: 1    MAIRVIPCLDVK-----DGRVVKGVNF--------VGLRDAGDPVELAAEYGRLGADEVT 47

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   A   G     E++   +E VFVPLTVGGG+R   D                R
Sbjct: 48   FLDIS---ASTEGRATTREMVTRCAETVFVPLTVGGGVRGVDD-----------VDVLLR 93

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+ + + A+                 +++++  +GNQ +V+S+D RR     PD  
Sbjct: 94   AGADKVGVNTAAI------------AHPGMIDEVADRFGNQVIVLSVDARR----EPDR- 136

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                       P G     +  T  GG  S  + A E A    E GAGEILLN +D DG 
Sbjct: 137  -----------PSG-----FGVTTHGGTRSAGLDAVEWACQAVERGAGEILLNSMDADGT 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFDI++I+ V  AV +P+IAS GAG V  F E   +    A LAA +FH   + I  +
Sbjct: 181  ADGFDIEMIEAVRAAVDVPLIASGGAGKVADFVEA-ARAGVDAVLAASVFHYHTLTIAQI 239

Query: 1746 KEHLVDAGVEVR 1781
            K+ L  AG EVR
Sbjct: 240  KDGLRHAGFEVR 251

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>Q3AT63:HIS5_CHLCH Imidazole glycerol phosphate synthase subunit hisH - Chlorobium|
           chlorochromatii (strain CaD3)
          Length = 201

 Score =  148 bits (373), Expect = 9e-35
 Identities = 85/199 (42%), Positives = 111/199 (55%), Gaps = 1/199 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V + DYGAGN+RSV  A   LG        P  +    +++ PGVGAFG AM  L   G 
Sbjct: 2   VFIADYGAGNLRSVLKAFEFLGIKAIVSNDPRKMAGYRKVLLPGVGAFGQAMQSLEALGF 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
             AL E++      LGICLG+QLL   SEE G   GL ++PG V+ F SS   I P IGW
Sbjct: 62  VSALLEHVDKGGHLLGICLGMQLLLSESEEMGTHKGLNLVPGKVKHFVSSSDKI-PQIGW 120

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           NA+  +K + L +  AD    YFVHSY+   +++ +   + T   G++F S+I    I A
Sbjct: 121 NAVDFSKQSDLFRNVADHSFFYFVHSYYC-ETESVEAVAATTLFAGQNFCSAIEKNGIFA 179

Query: 735 VQFHPEKSGATGLNIFENF 791
           VQFHPEKS   GL +  NF
Sbjct: 180 VQFHPEKSADAGLKVLANF 198

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>Q7V2P2:HIS6_PROMP Imidazole glycerol phosphate synthase subunit hisF - Prochlorococcus|
            marinus subsp. pastoris (strain CCMP 1378 / MED4)
          Length = 255

 Score =  147 bits (372), Expect = 1e-34
 Identities = 108/312 (34%), Positives = 160/312 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A R+I CLDV    NG +V  KG  +          +R+ G PVELA +Y   GADE+ 
Sbjct: 2    VALRLIPCLDVA---NGRVV--KGVNF--------VNLRDSGDPVELACKYSEAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I   RA       +++++   ++ V +P TVGGGI           +S+   ++  R
Sbjct: 49   FLDI---RASVENRKTLVDLVSRTAKSVKIPFTVGGGI-----------NSINSINDLLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV                 + + S  +G Q +V++ID R+   K     
Sbjct: 95   AGADKVSLNSSAV------------KNPDIISKSSTNFGTQCIVIAIDARKKITK----- 137

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                            Y  ++  V GGR++  +     AK VEELGAGEILL  +D DG 
Sbjct: 138  ----------------YNEWEVYVKGGRENTGLDVISWAKKVEELGAGEILLTSMDGDGT 181

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L + V++AV IPVIAS GAG+VE   +VF K  ASAAL A + H K++ I  +
Sbjct: 182  QNGYDLLLTQTVANAVNIPVIASGGAGSVEDIYDVFTKGKASAALLASLLHDKKLTIDEI 241

Query: 1746 KEHLVDAGVEVR 1781
            K  L++  + +R
Sbjct: 242  KSFLIEKKLPIR 253

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>Q4ZLP9:HIS5_PSEU2 Imidazole glycerol phosphate synthase subunit hisH - Pseudomonas|
           syringae pv. syringae (strain B728a)
          Length = 212

 Score =  147 bits (372), Expect = 1e-34
 Identities = 87/206 (42%), Positives = 120/206 (58%), Gaps = 7/206 (3%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILA-ADRLVFPGVGAFGSAMDVLNRT 371
           TV ++DYG GN+ SV  A+ H+G     + S   ++  ADR+VFPGVGA    M  + R 
Sbjct: 3   TVAVIDYGMGNLHSVAKALEHVGAGRVLITSDAKVIREADRIVFPGVGAIRDCMAEIRRL 62

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEGL 536
           G  D+L + +  DRPFLGIC+G+Q L DSSEENG V  +G+ PG V+ F     +  E L
Sbjct: 63  GF-DSLVQEVSQDRPFLGICVGMQALLDSSEENGGVDCIGMFPGQVKFFGKDLHEEGEHL 121

Query: 537 IVPHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSI 713
            VPH+GWN +    D  L     D    YFVHS++     AN+  +    +YG  F +++
Sbjct: 122 KVPHMGWNQVAQAVDHPLWHDIPDQARFYFVHSFYI--DAANQRQVVGRGHYGLDFAAAL 179

Query: 714 SMGNIQAVQFHPEKSGATGLNIFENF 791
           + G+  AVQFHPEKS   GL + +NF
Sbjct: 180 ADGSRFAVQFHPEKSHTHGLQLLQNF 205

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>Q31AG5:HIS5_PROM9 Imidazole glycerol phosphate synthase subunit hisH -|
           Prochlorococcus marinus (strain MIT 9312)
          Length = 205

 Score =  147 bits (372), Expect = 1e-34
 Identities = 85/202 (42%), Positives = 119/202 (58%), Gaps = 2/202 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+DYG GN+ SV  ++  LG  I  +++  +  A   ++ PGVGAF  AM  L  T +
Sbjct: 4   IGLIDYGMGNIHSVTKSLESLGEEIILIKNFSESKACKAIILPGVGAFDPAMINLINTDL 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              L+ +I   + FLGICLGLQLLF+SS+E G V GLG++ G +++  +     +PH+GW
Sbjct: 64  IIDLKNWINSGKSFLGICLGLQLLFESSDE-GKVQGLGILKGKIQKIPNIVNQRIPHMGW 122

Query: 558 NALQITKDTQLLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYG-ESFISSISMGNIQ 731
             L  TK   LL+  +    VYFVHSYHA+P D +   I+   NYG E   + I   N+ 
Sbjct: 123 CELLPTKTNTLLELEELNNWVYFVHSYHAIPDDFS--IIAAQVNYGSEKLTAMIENDNLL 180

Query: 732 AVQFHPEKSGATGLNIFENFLS 797
           A QFHPEKSG TG  +   +LS
Sbjct: 181 ACQFHPEKSGKTGEKLLRRWLS 202

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>P62450:HIS6_DESVH Imidazole glycerol phosphate synthase subunit hisF - Desulfovibrio|
            vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)
          Length = 259

 Score =  147 bits (371), Expect = 2e-34
 Identities = 108/313 (34%), Positives = 158/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L+KR+I CLDVR+       +TKG +++           ++G PV  A +YY +GADE+ 
Sbjct: 2    LSKRIIPCLDVRAGR-----LTKGVKFEGNV--------DIGDPVATARRYYEEGADEIV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            F +IT         L ++E  R ASE +F+P +VGGGI    D                 
Sbjct: 49   FYDITASHEDRGIFLDVVE--RVASE-IFIPFSVGGGINTVDDMRA-----------VLM 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GA+K+S+ S AV   +             + Q +  +G+QA+VV +D ++V        
Sbjct: 95   AGAEKVSVNSGAVKTPDI------------ISQGAAAFGSQAIVVGMDVKQV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                 + S+  P G     Y+  + GGR    + A E AK  E LGAGE+ +N ID DG 
Sbjct: 135  -----EKSATIPSG-----YEIVIHGGRKYMGMDAIEWAKTCESLGAGELCVNSIDADGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+++ L +M+SDAVTIPVIAS GAG+ EH  +   +  ASAAL A I H     I  +
Sbjct: 185  KDGYELTLTRMISDAVTIPVIASGGAGSPEHMYDALTRGGASAALIASIVHYGTYTIPDL 244

Query: 1746 KEHLVDAGVEVRM 1784
            K  +   G ++RM
Sbjct: 245  KRRISGMGAKMRM 257

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>Q9K6Z6:HIS6_BACHD Imidazole glycerol phosphate synthase subunit hisF - Bacillus|
            halodurans
          Length = 252

 Score =  147 bits (371), Expect = 2e-34
 Identities = 111/312 (35%), Positives = 152/312 (48%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L KR+I CLDV+     D  V KG Q+         ++R+ G PVELA+ Y   GADE+ 
Sbjct: 2    LTKRIIPCLDVK-----DGRVVKGVQF--------VDLRDAGDPVELAAFYDEQGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   M++V+   +  + +P TVGGGI           +SLE      R
Sbjct: 49   FLDISASHE---GRETMIDVVEKVAGTLAIPFTVGGGI-----------NSLEDMKRVLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + AV   E             + + +  +G+Q +VV+ID +          
Sbjct: 95   AGADKVSLNTAAVTRPEL------------ITEGADYFGSQCIVVAIDAK---------- 132

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                          E    ++    GGR        + A+     GAGEILL  +D DG 
Sbjct: 133  ------------YDEALGSWRIYTHGGRTPTEWEVCDWAREAVRRGAGEILLTSMDQDGA 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L   VS+AV++PVIAS GAGA E F +VF    A AALAA IFH KE  +  V
Sbjct: 181  KTGFDLALTTKVSEAVSVPVIASGGAGAKEDFVDVFMNAYADAALAASIFHYKETSVAEV 240

Query: 1746 KEHLVDAGVEVR 1781
            K HL + GV VR
Sbjct: 241  KTHLREEGVAVR 252

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>Q7V127:HIS5_PROMP Imidazole glycerol phosphate synthase subunit hisH -|
           Prochlorococcus marinus subsp. pastoris (strain CCMP
           1378 / MED4)
          Length = 205

 Score =  147 bits (371), Expect = 2e-34
 Identities = 79/201 (39%), Positives = 121/201 (60%), Gaps = 2/201 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+DYG GN+ SV  A+  L   I  +++   I     L+ PGVG+F  A++ L++T +
Sbjct: 4   IGLIDYGMGNIHSVTKALESLEEEIILIKNNHQIKDCKALILPGVGSFDPAINNLSKTEL 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              ++ +I+  + FLGICLGLQLLF+SS+E G ++GLG++ G +++        +PH+GW
Sbjct: 64  IIDIKNWIKSGKSFLGICLGLQLLFESSDE-GTINGLGIVKGQIKKIPQLSDQRIPHVGW 122

Query: 558 NALQITKDTQLLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYG-ESFISSISMGNIQ 731
             L  T+   LL+  +    VYFVHSYHA+PS  N + I+   +YG E   + I   N+ 
Sbjct: 123 CELLPTRKNSLLKVDELNNWVYFVHSYHAVPS--NNNLITANVSYGSEKLTAMIERDNLM 180

Query: 732 AVQFHPEKSGATGLNIFENFL 794
           A QFHPEKSG TG  +   ++
Sbjct: 181 ACQFHPEKSGKTGEKLLRRWI 201

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>Q31CA5:HIS6_PROM9 Imidazole glycerol phosphate synthase subunit hisF - Prochlorococcus|
            marinus (strain MIT 9312)
          Length = 256

 Score =  147 bits (370), Expect = 2e-34
 Identities = 104/312 (33%), Positives = 158/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A R+I CLDV         V KG  +          +R+ G PVELA +Y  +GADE+ 
Sbjct: 2    VALRLIPCLDVAHGR-----VVKGVNF--------VNLRDSGDPVELACRYSDEGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I   RA       +++++   ++ V +P TVGGGI            S+   ++  R
Sbjct: 49   FLDI---RASVENRNTLVDLVSRTAKSVKIPFTVGGGI-----------DSVSSINDLLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV                 + + SR +GNQ +V++ID +R   K+ +  
Sbjct: 95   AGADKVSLNSSAV------------RNPDLISKSSREFGNQCIVIAIDAKRKVNKTDE-- 140

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               ++  V GGR++  I     AK VEELGAGEILL  +D DG 
Sbjct: 141  -------------------WEVYVKGGRENTGIDVLSWAKKVEELGAGEILLTSMDGDGT 181

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L + V++ V IPVIAS GAG +E   +VF +  ASAAL A + H K++ +  +
Sbjct: 182  QNGYDLHLTESVANIVNIPVIASGGAGCLEDIYDVFNEGRASAALLASLLHDKKLSLREI 241

Query: 1746 KEHLVDAGVEVR 1781
            K  L++  + +R
Sbjct: 242  KTFLLERKLPIR 253

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>Q8ESS2:HIS6_OCEIH Imidazole glycerol phosphate synthase subunit hisF - Oceanobacillus|
            iheyensis
          Length = 254

 Score =  147 bits (370), Expect = 2e-34
 Identities = 106/312 (33%), Positives = 156/312 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG ++         +++++  PVELA +Y  +GADE+ 
Sbjct: 2    LAKRIIPCLDV---DNGRVV--KGKKF--------LDIQDVADPVELAKRYNDEGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            F +IT            L+V+   ++++ +P  VGGGIR   D             +  R
Sbjct: 49   FYDITASNE---QRGIFLDVVEKVAKEIAIPFMVGGGIRTTKD-----------IHQVLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            SGADK+SI S AV   E   ++  K            +G+Q  V+SID + + V      
Sbjct: 95   SGADKVSINSAAVQRPELIFESAQK------------FGSQCTVLSIDAKEIAVGK---- 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               +   ++GGR    I A E AK  E  GAGEI++N +D DG+
Sbjct: 139  -------------------WNVFINGGRKDTGIDAIEWAKKGESYGAGEIVVNAMDADGE 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+++ L   ++ AV IPVIAS GAG ++HF +V       AALAA +FH  E+ I A+
Sbjct: 180  KNGYNLPLTTAIATAVNIPVIASGGAGNIQHFKDVLSH-EIDAALAASVFHYDEIKIPAL 238

Query: 1746 KEHLVDAGVEVR 1781
            K +L +  + VR
Sbjct: 239  KTYLNEQEISVR 250

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>Q9JVH5:HIS6_NEIMA Imidazole glycerol phosphate synthase subunit hisF - Neisseria|
            meningitidis serogroup A
          Length = 255

 Score =  147 bits (370), Expect = 2e-34
 Identities = 106/313 (33%), Positives = 159/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV+     D  V KG  +          +R+ G PVE A +Y  +GADE++
Sbjct: 3    LAKRIIPCLDVK-----DGRVVKGVNFI--------GLRDAGDPVEAAKRYNGEGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       +L ++   + +VF+PLTVGGG+R   D                 
Sbjct: 50   FLDIT---ASSDNRDTILHIIEEVAGQVFIPLTVGGGVRTVAD-----------IRRLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV            T    +++ +  +G+QA+V ++D + V   +P+  
Sbjct: 96   AGADKVSINTAAV------------TRPDLIDEAAGFFGSQAIVAAVDAKAV---NPENT 140

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
            +                  ++    GGR+   + A E A  +++ GAGEILL  +D DG 
Sbjct: 141  R------------------WEIFTHGGRNPTGLDAVEWAIEMQKRGAGEILLTGMDRDGT 182

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GF++ L + V++AV IPVIAS G G V H  E   +  A A LAAG+FH  E+ I   
Sbjct: 183  KQGFNLPLTRAVAEAVDIPVIASGGVGNVRHLIEGITEGKADAVLAAGVFHFGEIAIREA 242

Query: 1746 KEHLVDAGVEVRM 1784
            K  + +AG+EVR+
Sbjct: 243  KHAMREAGIEVRL 255

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>Q5FA23:HIS6_NEIG1 Imidazole glycerol phosphate synthase subunit hisF - Neisseria|
            gonorrhoeae (strain ATCC 700825 / FA 1090)
          Length = 255

 Score =  147 bits (370), Expect = 2e-34
 Identities = 107/313 (34%), Positives = 158/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV+     D  V KG  +          +R+ G PVE A +Y  +GADE++
Sbjct: 3    LAKRIIPCLDVK-----DGRVVKGVNFI--------GLRDAGDPVEAAKRYNGEGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       +L ++   + +VF+PLTVGGG+R   D                 
Sbjct: 50   FLDIT---ASSDNRDTILHIIEEVAGQVFIPLTVGGGVRTVAD-----------IRRLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV            T    + + +  +G+QA+V ++D + V   +P+  
Sbjct: 96   AGADKVSINTAAV------------TRPDLINEAAGFFGSQAIVAAVDAKAV---NPENT 140

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
            +                  ++    GGR+   + A E A  +++ GAGEILL  +D DG 
Sbjct: 141  R------------------WEIFTHGGRNPTGLDAVEWAVEMQKRGAGEILLTGMDRDGT 182

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GF++ L + V++AV IPVIAS G G V H  E   +  A A LAAGIFH  E+ I   
Sbjct: 183  KQGFNLPLTRAVAEAVDIPVIASGGVGNVRHLIEGITEGKADAVLAAGIFHFGEIAIREA 242

Query: 1746 KEHLVDAGVEVRM 1784
            K  + +AG+EVR+
Sbjct: 243  KRTMREAGIEVRL 255

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>Q8KCB0:HIS6_CHLTE Imidazole glycerol phosphate synthase subunit hisF - Chlorobium|
            tepidum
          Length = 251

 Score =  147 bits (370), Expect = 2e-34
 Identities = 116/313 (37%), Positives = 160/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDVR     D  V KG  ++         +R+ G  +E A  Y  + ADE+ 
Sbjct: 2    LAKRIIPCLDVR-----DGRVVKGINFE--------GLRDAGSILEQARFYNNEMADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+   +       + EVL+ + E VF+PLTVGGGI           SS+E A + F 
Sbjct: 49   FLDISA--SLESRRTTLEEVLKVSGE-VFIPLTVGGGI-----------SSVERAHDAFL 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+S+ + AV   E             + +I+  +G+QAVVV+ID ++V        
Sbjct: 95   HGADKVSVNTAAVSEPEL------------ISRIAEKFGSQAVVVAIDVKKV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
              R +  +  G    EY                 A E A  V+ELGAGEILL  +D DG 
Sbjct: 135  DGRYIVHTHSGKKPTEYE----------------AVEWAHKVQELGAGEILLTSMDRDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D +++KM+S  V IPVIAS GAG +EH    F   +A AALAA IFH +   I   
Sbjct: 179  QEGYDNEILKMISTTVHIPVIASGGAGNLEHLYRGFTDGHADAALAASIFHFRTYSIRQA 238

Query: 1746 KEHLVDAGVEVRM 1784
            KE+L + G+ VR+
Sbjct: 239  KEYLRERGITVRL 251

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>Q6F799:HIS6_ACIAD Imidazole glycerol phosphate synthase subunit hisF - Acinetobacter|
            sp. (strain ADP1)
          Length = 252

 Score =  147 bits (370), Expect = 2e-34
 Identities = 109/313 (34%), Positives = 157/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV   DNG +V  KG Q+         ++R+ G PVE+A +Y   GADE++
Sbjct: 2    LAKRIIPCLDV---DNGRVV--KGVQF--------LDIRDAGDPVEVARRYNEQGADEIT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A   G       +   +E VFVPLTVGGG+R   D                 
Sbjct: 49   FLDIT---ATHHGRDTTYRTVERMAESVFVPLTVGGGVRKVED-----------IRLLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S AVF  E             +++ S+ +G Q +VV+ID +    K+ D  
Sbjct: 95   AGADKVSINSAAVFNPEF------------VQEASQRFGAQCIVVAIDAK----KTGDNT 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               ++    GGR    I A E +  + E GAGE+L+  +D DG 
Sbjct: 139  -------------------WEIFTHGGRKPTGIDALEWSVKMAEYGAGELLVTSMDADGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L++ +++ V+IP IAS G G ++H ++   K  A A LAA IFH  +  I   
Sbjct: 180  KAGYDIALMREINNRVSIPTIASGGVGNLQHMADGILKGGADAVLAASIFHFGQHTIPEA 239

Query: 1746 KEHLVDAGVEVRM 1784
            K+ L   G+E+R+
Sbjct: 240  KQFLAAQGIEMRL 252

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>Q31E66:HIS5_THICR Imidazole glycerol phosphate synthase subunit hisH - Thiomicrospira|
           crunogena (strain XCL-2)
          Length = 213

 Score =  147 bits (370), Expect = 2e-34
 Identities = 90/212 (42%), Positives = 122/212 (57%), Gaps = 6/212 (2%)
 Frame = +3

Query: 186 DANTVTLLDYGAGNVRSVRNAIRHLG-FNIRDVRSP--EDILAADRLVFPGVGAFGSAMD 356
           D   VT++DYG GN+RSV  A  H    N R   S   EDI +AD ++FPG GA  + M 
Sbjct: 3   DQKLVTVIDYGMGNLRSVAKAAEHAADSNTRICISDKAEDIRSADAIIFPGQGAAKACMK 62

Query: 357 VLNRTGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSS--E 530
            LN T +  AL +    ++PFLGIC+GLQ+L   S+EN  V  L ++ G V++FD S   
Sbjct: 63  ALNETNITHALIQ-AATEKPFLGICMGLQVLMTHSQENEGVDCLDILKGDVQKFDLSGHP 121

Query: 531 GLIVPHIGWNALQITKDTQLLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYGESFIS 707
            L +PH+GWN +  T D  L    +     YFVHSY   P D  K  I+    +G+ F S
Sbjct: 122 ELKMPHMGWNQIHQTIDHPLWHNIEQNSRFYFVHSYFVSPHD--KQIIAGETTHGKRFTS 179

Query: 708 SISMGNIQAVQFHPEKSGATGLNIFENFLSPN 803
           +I+  N+ A+Q HPEKS   GL +F+NFL+ N
Sbjct: 180 AIAQNNLFAIQAHPEKSADAGLQLFKNFLNWN 211

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>Q7U899:HIS52_SYNPX Imidazole glycerol phosphate synthase subunit hisH 2 -|
           Synechococcus sp. (strain WH8102)
          Length = 212

 Score =  147 bits (370), Expect = 2e-34
 Identities = 85/206 (41%), Positives = 117/206 (56%), Gaps = 2/206 (0%)
 Frame = +3

Query: 204 LLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGMAD 383
           L+DYG GN+ SV  A   LG     V +P D+   D LV PGVG+F  A+D L  TG+  
Sbjct: 7   LIDYGMGNLHSVEKAFNRLGHQPSRVVNPSDLDGCDALVLPGVGSFDPAIDNLQSTGLIP 66

Query: 384 ALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGWNA 563
            L+ +   DRP LGICLGLQLLF+SS E G + GLG+I G V R     G  +PH+GW  
Sbjct: 67  DLKRWNEADRPLLGICLGLQLLFESSAE-GRLEGLGLIKGHVERLPIGAGARIPHMGWAP 125

Query: 564 LQITKDTQLLQGADG-QHVYFVHSYHALPSDANKDWISLTCNYGESFISS-ISMGNIQAV 737
           L + +   +L  AD    VYFVHSY A+P     + ++   ++G S +++ +    + A 
Sbjct: 126 LDLRRANPMLAAADPLAWVYFVHSYAAVPE--RPETLAAAASFGSSSVTAMVWQRRLGAC 183

Query: 738 QFHPEKSGATGLNIFENFLSPNSSGA 815
           QFHPEKS  +G  + + +L     GA
Sbjct: 184 QFHPEKSSDSGSAMLKRWLDWLQRGA 209

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>Q5WYE9:HIS51_LEGPL Imidazole glycerol phosphate synthase subunit hisH 1 - Legionella|
           pneumophila (strain Lens)
          Length = 213

 Score =  147 bits (370), Expect = 2e-34
 Identities = 85/211 (40%), Positives = 123/211 (58%), Gaps = 10/211 (4%)
 Frame = +3

Query: 192 NTVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRT 371
           ++V++LDYG GN+ SV  A ++   ++  V +PE+I++ADRLV PGVGAF   M  L   
Sbjct: 2   SSVSILDYGVGNLLSVARAFQYFDASVNLVSTPEEIMSADRLVLPGVGAFEDGMKGLTTL 61

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSS--EGLI-- 539
              + ++++ R  +PFLGICLG+Q++   S E G   GLG+I G V    S   +G +  
Sbjct: 62  NFIEPIKQFARSGKPFLGICLGMQMMLSKSTEFGQHEGLGLIAGEVVSVPSHGVDGQLHK 121

Query: 540 VPHIGWNALQITKD------TQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESF 701
           +PHIGWN L  T +      T L        VYFVHS+ A+PS+  K  ++ T   G++ 
Sbjct: 122 IPHIGWNELVSTSEGEDWCHTILKNIPLNSSVYFVHSFMAMPSNPKKR-LADTLYDGQAI 180

Query: 702 ISSISMGNIQAVQFHPEKSGATGLNIFENFL 794
            + I   N+   QFHPEKSG  GL+I + FL
Sbjct: 181 SAVIKDENMYGCQFHPEKSGEVGLSIIQQFL 211

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>Q3J6Q1:HIS6_NITOC Imidazole glycerol phosphate synthase subunit hisF - Nitrosococcus|
            oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 257

 Score =  146 bits (369), Expect = 3e-34
 Identities = 109/312 (34%), Positives = 154/312 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV    NG +V  KG ++          +R+ G PVE+A +Y   GADE++
Sbjct: 3    LAKRIIPCLDVA---NGRVV--KGVRF--------VNIRDAGDPVEIARRYDEQGADEIT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       M+ V+   + +VF+PLTVGGGIR            LE       
Sbjct: 50   FLDIT---ASSDNRDTMVHVVEEVAAQVFIPLTVGGGIR-----------YLEDIRRLLI 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+ I + AV   E             + + +  +G+Q +VV+ID ++V        
Sbjct: 96   AGADKVGINTAAVQRPEL------------VREAAERFGSQCIVVAIDAKQV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                          +E   ++    GGR    + A   A+ + E GAGEILL  +D DG 
Sbjct: 136  -----------SSADEPPQWEVFTHGGRKETGLDAVAWARQMVEFGAGEILLTSMDRDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + +S+A+ +PVIAS G G +EH      +  A A LAA IFH  E  I   
Sbjct: 185  REGFDLPLTRTISEAIPVPVIASGGVGTLEHLVAGILEGKADAVLAASIFHFGEYTIAEA 244

Query: 1746 KEHLVDAGVEVR 1781
            KEHL   G+E+R
Sbjct: 245  KEHLSAHGIEMR 256

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>Q3KJI8:HIS5_PSEPF Imidazole glycerol phosphate synthase subunit hisH - Pseudomonas|
           fluorescens (strain PfO-1)
          Length = 212

 Score =  146 bits (369), Expect = 3e-34
 Identities = 86/206 (41%), Positives = 119/206 (57%), Gaps = 7/206 (3%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILA-ADRLVFPGVGAFGSAMDVLNRT 371
           TV ++DYG GN+ SV  A+ H+G     + S   ++  ADR+VFPGVGA    M  + R 
Sbjct: 3   TVAVIDYGMGNLHSVAKALEHVGAGKVLITSDAAVIREADRVVFPGVGAIRDCMAEIRRL 62

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEGL 536
           G    +RE +  DRPFLGIC+G+Q L DSSEEN  V  +G+ PG V+ F     +  E L
Sbjct: 63  GFDSLVRE-VSQDRPFLGICVGMQALLDSSEENDGVDCIGLFPGAVKFFGKDLHEDGEHL 121

Query: 537 IVPHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSI 713
            VPH+GWN ++   D  L     D    YFVHSY+   +  N   +  + +YG  F +++
Sbjct: 122 KVPHMGWNEVKQAVDHPLWHNIPDLARFYFVHSYYI--AAGNPRQVVGSGHYGVDFAAAL 179

Query: 714 SMGNIQAVQFHPEKSGATGLNIFENF 791
           + G+  AVQFHPEKS   GL + +NF
Sbjct: 180 AEGSRFAVQFHPEKSHTHGLQLLQNF 205

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>Q603K1:HIS5_METCA Imidazole glycerol phosphate synthase subunit hisH - Methylococcus|
           capsulatus
          Length = 217

 Score =  146 bits (369), Expect = 3e-34
 Identities = 85/211 (40%), Positives = 122/211 (57%), Gaps = 10/211 (4%)
 Frame = +3

Query: 192 NTVTLLDYGAGNVRSVRNAIRHLGFN--IRDVRSPEDILAADRLVFPGVGAFGSAMDVLN 365
           ++V ++DYG GN+ S+  A++H   N  +     P+ ILA+DR+VFPGVGA    M  L 
Sbjct: 2   SSVAVIDYGMGNLHSIAKALQHADANAAVTVTSDPDVILASDRVVFPGVGAMRDCMAHLA 61

Query: 366 RTGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFD------SS 527
              +   +R     ++PFLGICLG+Q L + SEENG    LG+I G V RF       + 
Sbjct: 62  ERRLEQVVRR-AAAEKPFLGICLGMQALLEESEENGGTRCLGLITGRVLRFPEGLTGAAG 120

Query: 528 EGLIVPHIGWNALQITKDTQ-LLQGADGQH-VYFVHSYHALPSDANKDWISLTCNYGESF 701
           E L +PH+GWN +  +  +  L  G   +   YFVHSY+A P+D     ++ T +Y   F
Sbjct: 121 EPLKIPHMGWNRVHFSDPSHPLWAGIPAESWFYFVHSYYAAPADPAD--VAATSDYPTPF 178

Query: 702 ISSISMGNIQAVQFHPEKSGATGLNIFENFL 794
            ++++ G + AVQFHPEKS A GL +  NFL
Sbjct: 179 AAAVARGKVFAVQFHPEKSQAAGLRLLANFL 209

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>Q47AM1:HIS5_DECAR Imidazole glycerol phosphate synthase subunit hisH - Dechloromonas|
           aromatica (strain RCB)
          Length = 215

 Score =  146 bits (369), Expect = 3e-34
 Identities = 89/210 (42%), Positives = 121/210 (57%), Gaps = 10/210 (4%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHL--GFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNR 368
           T+ ++DYG GN+RSV  A+ H+  G  +     P  + AA+R+VFPG GA    M  L+ 
Sbjct: 7   TIAVIDYGMGNLRSVSKALEHVAGGKQVIVTADPAVVAAAERVVFPGQGAMPDCMRELDA 66

Query: 369 TGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFD-------SS 527
            G+  A+    + D+PFLGIC+G Q+LF+ S+E G V  LGV  G V+RF        + 
Sbjct: 67  RGLRTAVLAAAK-DKPFLGICVGEQMLFEHSDE-GNVPALGVFAGNVKRFPDEKMHLPTG 124

Query: 528 EGLIVPHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFI 704
           E L VPH+GWN ++  K   L  G ADG   YFVHSY   P+D     ++  C YG  F 
Sbjct: 125 ERLKVPHMGWNEVR-QKPHALWSGIADGSRFYFVHSYFVEPADLAL--VTGICEYGVPFT 181

Query: 705 SSISMGNIQAVQFHPEKSGATGLNIFENFL 794
            ++   NI AVQFHPEKS   GL + +NF+
Sbjct: 182 CAVGRDNIFAVQFHPEKSARDGLQLLKNFV 211

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>P61783:HIS52_METMP Imidazole glycerol phosphate synthase subunit hisH 2 -|
           Methanococcus maripaludis
          Length = 202

 Score =  146 bits (369), Expect = 3e-34
 Identities = 81/201 (40%), Positives = 115/201 (57%), Gaps = 2/201 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GNV S++N I  +GF+      PE I  A +L+ PGVG+F S M  L   G+
Sbjct: 2   IAIIDYGMGNVGSIKNMIAKIGFDAIITNDPELISKATKLILPGVGSFDSGMTNLKELGL 61

Query: 378 ADALREYIRMDR-PFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIG 554
            D L + +  ++ P LGICLG+ LL +SSEE G + GLG I     +F  S    +PH+G
Sbjct: 62  IDILNKKVVQEKTPLLGICLGMHLLTNSSEE-GRLKGLGFINAKTVKFKLSNKFKIPHMG 120

Query: 555 WNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           WN ++ +   +L     +    YFVHSY+ +  D  K  I +T  Y   F S++S  NI 
Sbjct: 121 WNYVKFSIKNKLSDNLIENSRFYFVHSYYVICED--KKNILMTTEYENEFTSAVSKDNIY 178

Query: 732 AVQFHPEKSGATGLNIFENFL 794
            VQFHPEKS   G+ + ENF+
Sbjct: 179 GVQFHPEKSHKFGMKLMENFI 199

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>Q9K0H4:HIS6_NEIMB Imidazole glycerol phosphate synthase subunit hisF - Neisseria|
            meningitidis serogroup B
          Length = 255

 Score =  146 bits (368), Expect = 4e-34
 Identities = 106/313 (33%), Positives = 158/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV+     D  V KG  +          +R+ G PVE A +Y  +GADE++
Sbjct: 3    LAKRIIPCLDVK-----DGRVVKGVNFI--------GLRDAGDPVEAAKRYNGEGADELT 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       +L ++   + +VF+PLTVGGG+R   D                 
Sbjct: 50   FLDIT---ASSDNRDTILHIIEEVAGQVFIPLTVGGGVRTVAD-----------IRRLLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV            T    +++ +  +G+QA+V ++D +     +P+  
Sbjct: 96   AGADKVSINTAAV------------TRPDLIDEAAGFFGSQAIVAAVDAKAA---NPENT 140

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
            +                  ++    GGR+   + A E A  +++ GAGEILL  +D DG 
Sbjct: 141  R------------------WEIFTHGGRNPTGLDAVEWAVEMQKRGAGEILLTGMDRDGT 182

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GF++ L + V++AV IPVIAS G G V H  E   +  A A LAAGIFH  E+ I   
Sbjct: 183  KQGFNLPLTRAVAEAVDIPVIASGGVGNVRHLIEGITEGKADAVLAAGIFHFGEIAIREA 242

Query: 1746 KEHLVDAGVEVRM 1784
            K  + +AG+EVR+
Sbjct: 243  KRAMREAGIEVRL 255

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>Q4KJS7:HIS5_PSEF5 Imidazole glycerol phosphate synthase subunit hisH - Pseudomonas|
           fluorescens (strain Pf-5 / ATCC BAA-477)
          Length = 212

 Score =  146 bits (368), Expect = 4e-34
 Identities = 87/206 (42%), Positives = 119/206 (57%), Gaps = 7/206 (3%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILA-ADRLVFPGVGAFGSAMDVLNRT 371
           TV ++DYG GN+ SV  A+ H+G     + S   ++  ADR+VFPGVGA    M  + R 
Sbjct: 3   TVAVIDYGMGNLHSVAKALEHVGAGKVLITSDASVIREADRVVFPGVGAIRDCMAEIRRL 62

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEGL 536
           G  DAL   +  DRPFLGIC+G+Q L D SEEN  V  +G+ PG V+ F     +  E L
Sbjct: 63  GF-DALVREVSQDRPFLGICVGMQALLDHSEENEGVDCIGLFPGQVKFFGKGLIEDGEHL 121

Query: 537 IVPHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSI 713
            VPH+GWN ++   D  L    AD    YFVHSY+   +  N   +  + +YG  F +++
Sbjct: 122 KVPHMGWNEVKQAVDHPLWHNIADLARFYFVHSYYI--NAGNTRQVVGSGHYGVDFAAAL 179

Query: 714 SMGNIQAVQFHPEKSGATGLNIFENF 791
           + G+  AVQFHPEKS   GL + +NF
Sbjct: 180 ADGSRFAVQFHPEKSHTHGLQLLQNF 205

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>Q5N0H4:HIS6_SYNP6 Imidazole glycerol phosphate synthase subunit hisF - Synechococcus|
            sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)
            (Anacystis nidulans)
          Length = 255

 Score =  145 bits (367), Expect = 5e-34
 Identities = 105/312 (33%), Positives = 154/312 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR++ CLDV++       V KG  +         ++R+ G PVELA  Y   GADE+ 
Sbjct: 2    LAKRILPCLDVKAGR-----VVKGVNF--------VDLRDAGDPVELAQAYDAAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I            +++V+   +E+VF+PLTV GGI D           LE   +  R
Sbjct: 49   FLDIAATHE---ERQILVDVVYRTAEQVFIPLTVSGGIND-----------LETIRQLPR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI S A    +             + + S  +G+Q +VV+ID RR         
Sbjct: 95   AGADKVSINSAAARDPDL------------IRRASDRFGSQCIVVAIDARR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                 +     P  + Y      V GGR++  I A   A+ V   GAGE+L+  +D DG 
Sbjct: 134  -----RTDPDNPGWDVY------VRGGRENTGIDALTWAETVARNGAGELLVTSMDADGT 182

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D++L + ++D V IPVIAS GAG  E  +E F   +A AAL A + H  ++ I  +
Sbjct: 183  QAGYDLELTRAIADRVEIPVIASGGAGTCEDIAEAFRTGHAEAALLASLLHYGQLTIAEI 242

Query: 1746 KEHLVDAGVEVR 1781
            K+HL  A +  R
Sbjct: 243  KDHLRSAQIPTR 254

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>Q4FPU1:HIS5_PSYAR Imidazole glycerol phosphate synthase subunit hisH - Psychrobacter|
           arcticum
          Length = 214

 Score =  145 bits (367), Expect = 5e-34
 Identities = 77/210 (36%), Positives = 120/210 (57%), Gaps = 8/210 (3%)
 Frame = +3

Query: 189 ANTVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNR 368
           A  + LLDYG GN+ S   A+  +G  +     P+ + AAD++ FPGVGA    +  ++ 
Sbjct: 4   ATKIALLDYGMGNLHSASKALSAVGAEVSITNDPKVVAAADKIFFPGVGAMRDCIAGMHE 63

Query: 369 TGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF------DSSE 530
            G+ D +R+ I  ++P + IC+G+Q LF+ S ENG    L ++ G V  F      +   
Sbjct: 64  AGIDDVIRQAI-FNKPVMAICVGMQALFEQSAENGGTPCLSILDGTVPAFNPEWKDEKGV 122

Query: 531 GLIVPHIGWNALQ-ITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFI 704
            + VPH+GWN +  +  +  L  G  D  H YFVHSY+  P+D+++  ++  C+YG+ F 
Sbjct: 123 QIKVPHMGWNTISGMNFEHPLWNGIEDKAHFYFVHSYYCEPADSSQ--VAAICDYGQPFC 180

Query: 705 SSISMGNIQAVQFHPEKSGATGLNIFENFL 794
           +SI   N+ A QFHPEKS   GL + +NF+
Sbjct: 181 ASILQDNLFATQFHPEKSHTAGLQLLKNFV 210

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>Q65EG1:HIS5_BACLD Imidazole glycerol phosphate synthase subunit hisH - Bacillus|
           licheniformis (strain DSM 13 / ATCC 14580)
          Length = 212

 Score =  145 bits (367), Expect = 5e-34
 Identities = 77/202 (38%), Positives = 115/202 (56%), Gaps = 4/202 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+ SV  A+  +         P+++  AD  + PGVGAF  AM++L   G+
Sbjct: 2   IGVIDYGMGNLYSVSKALERIDAPYFVSEHPDELKRADSYILPGVGAFRDAMEILTENGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPG-VVRRFDSSEG---LIVP 545
              ++      +P LGICLG+QLLF+ SEE+G   GLG++ G VV+  D  +    L VP
Sbjct: 62  KTFIQAAANEGKPLLGICLGMQLLFEESEEHGASEGLGLLKGKVVKLKDCDQAGNRLKVP 121

Query: 546 HIGWNALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGN 725
           H+GWN L++ +D+ LL  A     YFVHSY+   S   ++ +  +  YG    + + +GN
Sbjct: 122 HMGWNLLKVHRDSPLLPKAKEGFAYFVHSYYV--SGIEEEALLASAEYGVCVPAVVGLGN 179

Query: 726 IQAVQFHPEKSGATGLNIFENF 791
           +   QFHPEKS   G+ I E F
Sbjct: 180 VYGAQFHPEKSSTVGMLILERF 201

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>Q5NMD4:HIS5_ZYMMO Imidazole glycerol phosphate synthase subunit hisH - Zymomonas|
           mobilis
          Length = 229

 Score =  145 bits (366), Expect = 6e-34
 Identities = 89/211 (42%), Positives = 119/211 (56%), Gaps = 6/211 (2%)
 Frame = +3

Query: 189 ANTVTLLDYGAGNVRSVRNAIRHLGF---NIRDVRSPEDILAADRLVFPGVGAFGSAMDV 359
           ++TV L+DYGAGN+RSV NA+   G    N+    +P+++L ADR+V PGVGAF S M  
Sbjct: 22  SSTVALIDYGAGNLRSVANALLASGLARENLVVTANPDEVLQADRVVLPGVGAFASCMQA 81

Query: 360 LNRT-GMADALREYI-RMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSE- 530
           L     M  AL + +    RPFLGIC+G+QLL D  EE G   GLG I G V     ++ 
Sbjct: 82  LKAIPDMVPALEKAVLEKGRPFLGICVGMQLLADQGEEYGVHQGLGWIKGKVTPLRPNDP 141

Query: 531 GLIVPHIGWNALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISS 710
              VPH+GWN + +T D+  L  A     YF+HSY  +P D  +  +  T  +G    ++
Sbjct: 142 SCKVPHMGWNQIGLTTDSHPLLRAG--EAYFLHSYAFVPED--ESTLLATTEHGGLVTAA 197

Query: 711 ISMGNIQAVQFHPEKSGATGLNIFENFLSPN 803
           +   NI  VQFHPEKS + GL     FL  N
Sbjct: 198 VGRDNIMGVQFHPEKSQSYGLEFLSRFLDWN 228

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>Q316L3:HIS5_DESDG Imidazole glycerol phosphate synthase subunit hisH - Desulfovibrio|
           desulfuricans (strain G20)
          Length = 213

 Score =  145 bits (366), Expect = 6e-34
 Identities = 82/205 (40%), Positives = 112/205 (54%), Gaps = 7/205 (3%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + +L Y AGN  SVR A+ H+G        P +I A++ ++FPGVGA G AMD L   G+
Sbjct: 2   LAILKYKAGNQTSVRRALNHIGIPNVITADPAEIAASEGIIFPGVGAAGQAMDELTAAGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF------DSSEGLI 539
              L+E +   +P LGIC+G Q++ D S+EN     LG+IPG    F      ++   + 
Sbjct: 62  DAVLKEQVEAGKPLLGICVGCQIMLDYSQEN-DTRTLGIIPGECHLFNPALEDETGAPIR 120

Query: 540 VPHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSIS 716
           VPH+GWN +   K   L +G +D    YFVHSY   P     D++  T  YG+ F S   
Sbjct: 121 VPHMGWNRVIPRKPCALFKGISDDAEFYFVHSYFPNP---QPDYVIATTTYGKEFCSVHG 177

Query: 717 MGNIQAVQFHPEKSGATGLNIFENF 791
              + AVQFHPEKSG  GL +  NF
Sbjct: 178 GPGLWAVQFHPEKSGRPGLKLLSNF 202

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>P48262:HIS5_CYAPA Imidazole glycerol phosphate synthase subunit hisH - Cyanophora|
           paradoxa
          Length = 215

 Score =  145 bits (366), Expect = 6e-34
 Identities = 82/202 (40%), Positives = 120/202 (59%), Gaps = 3/202 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           ++++DY  GN+ SV   I   G   + + S E+I  A  L+ PGVG+F  AM  L +  +
Sbjct: 12  ISIIDYQMGNLYSVCKGIERSGGIPKIINSAEEIKKATALILPGVGSFDPAMKQLKKQDL 71

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + +++ I   +PFLGICLGL LLF+ SEE G  SGLG++ G V+R  +   + +PH+GW
Sbjct: 72  INPIKDAISEKKPFLGICLGLHLLFEESEE-GIESGLGILSGSVKRIKNEPEITIPHMGW 130

Query: 558 NALQITKDTQLLQGADGQH--VYFVHSYHALPSDANKDWISLTCNYG-ESFISSISMGNI 728
           N LQ+T     L     ++  VYFVHSY A P + N   I+    +G +   ++I   NI
Sbjct: 131 NQLQLTNPKCYLWDGLTKYPWVYFVHSYFAQPKNPNV--IAAAVTHGTQQVTAAIQYENI 188

Query: 729 QAVQFHPEKSGATGLNIFENFL 794
            AVQFHPEKS + GL++  NF+
Sbjct: 189 SAVQFHPEKSASIGLHMLNNFV 210

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>Q7MPP4:HIS52_VIBVY Imidazole glycerol phosphate synthase subunit hisH 2 - Vibrio|
           vulnificus (strain YJ016)
          Length = 214

 Score =  145 bits (366), Expect = 6e-34
 Identities = 87/202 (43%), Positives = 114/202 (56%), Gaps = 3/202 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLG-FNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTG 374
           + ++DY  GNVRS+ NAI H+G + I     P+ I +AD L+ PGVGAF  AM  L +  
Sbjct: 3   IVIIDYDMGNVRSIENAINHIGDYTIIVSGEPDTIRSADCLILPGVGAFPDAMKKLEQQK 62

Query: 375 MADALREYIRMDR-PFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHI 551
           + D L E + + R P LGICLG+QLLF+SSEE     GLG IPG V        L VPH+
Sbjct: 63  LIDLLTEEVVVRRKPVLGICLGMQLLFESSEEIQLTKGLGWIPGKVEYMRPGNDLRVPHV 122

Query: 552 GWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNI 728
           GWN+L + K+  L     D +  YFVHS   L  +  + +   T  YG    +S+   NI
Sbjct: 123 GWNSLILKKENSLFDYLQDDKDFYFVHS---LWVNCPEKYKLATFEYGIEMTASVQYENI 179

Query: 729 QAVQFHPEKSGATGLNIFENFL 794
             +QFHPEKS   GL    +FL
Sbjct: 180 VGMQFHPEKSQRNGLEAIRSFL 201

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>Q3Z0G2:HIS5_SHISS Imidazole glycerol phosphate synthase subunit hisH - Shigella|
           sonnei (strain Ss046)
          Length = 196

 Score =  145 bits (365), Expect = 8e-34
 Identities = 83/200 (41%), Positives = 116/200 (58%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V +LD G  N+ SV++AI   G+  +  R P+ +L AD+L  PGVG   +AMD +    +
Sbjct: 3   VVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVREREL 62

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            D ++      +P LGICLG+QLL   SEE+  V  LG+I   V +  +  GL +PH+GW
Sbjct: 63  FDLIKA---CTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKM-TDFGLPLPHMGW 118

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N +      +L QG  DG + YFVHSY A+P +    W    CNYGE F +++   N   
Sbjct: 119 NRVYPQAGNRLFQGIEDGAYFYFVHSY-AMPVNP---WTIAQCNYGEPFTAAVQKDNFYG 174

Query: 735 VQFHPEKSGATGLNIFENFL 794
           VQFHPE+SGA G  + +NFL
Sbjct: 175 VQFHPERSGAAGAKLLKNFL 194

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>Q83KJ5:HIS5_SHIFL Imidazole glycerol phosphate synthase subunit hisH - Shigella|
           flexneri
          Length = 196

 Score =  145 bits (365), Expect = 8e-34
 Identities = 83/200 (41%), Positives = 116/200 (58%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V +LD G  N+ SV++AI   G+  +  R P+ +L AD+L  PGVG   +AMD +    +
Sbjct: 3   VVILDTGCANLNSVKSAIARHGYEPKVSRDPDIVLLADKLFLPGVGTAQAAMDQVREREL 62

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            D ++      +P LGICLG+QLL   SEE+  V  LG+I   V +  +  GL +PH+GW
Sbjct: 63  FDLIKA---CTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKM-TDFGLPLPHMGW 118

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N +      +L QG  DG + YFVHSY A+P +    W    CNYGE F +++   N   
Sbjct: 119 NRVYPQAGNRLFQGIEDGAYFYFVHSY-AMPVNP---WTIAQCNYGEPFTAAVQKDNFYG 174

Query: 735 VQFHPEKSGATGLNIFENFL 794
           VQFHPE+SGA G  + +NFL
Sbjct: 175 VQFHPERSGAAGAKLLKNFL 194

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>Q32EF2:HIS5_SHIDS Imidazole glycerol phosphate synthase subunit hisH - Shigella|
           dysenteriae serotype 1 (strain Sd197)
          Length = 196

 Score =  145 bits (365), Expect = 8e-34
 Identities = 83/200 (41%), Positives = 116/200 (58%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V +LD G  N+ SV++AI   G+  +  R P+ +L AD+L  PGVG   +AMD +    +
Sbjct: 3   VVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVREREL 62

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            D ++      +P LGICLG+QLL   SEE+  V  LG+I   V +  +  GL +PH+GW
Sbjct: 63  FDLIKA---CTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKM-TDFGLPLPHMGW 118

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N +      +L QG  DG + YFVHSY A+P +    W    CNYGE F +++   N   
Sbjct: 119 NRVYPQAGNRLFQGIEDGAYFYFVHSY-AMPVNP---WTIAQCNYGEPFTAAVQKDNFYG 174

Query: 735 VQFHPEKSGATGLNIFENFL 794
           VQFHPE+SGA G  + +NFL
Sbjct: 175 VQFHPERSGAAGAKLLKNFL 194

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>Q323I9:HIS5_SHIBS Imidazole glycerol phosphate synthase subunit hisH - Shigella|
           boydii serotype 4 (strain Sb227)
          Length = 196

 Score =  145 bits (365), Expect = 8e-34
 Identities = 83/200 (41%), Positives = 116/200 (58%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V +LD G  N+ SV++AI   G+  +  R P+ +L AD+L  PGVG   +AMD +    +
Sbjct: 3   VVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVREREL 62

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            D ++      +P LGICLG+QLL   SEE+  V  LG+I   V +  +  GL +PH+GW
Sbjct: 63  FDLIKA---CTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKM-TDFGLPLPHMGW 118

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N +      +L QG  DG + YFVHSY A+P +    W    CNYGE F +++   N   
Sbjct: 119 NRVYPQAGNRLFQGIEDGAYFYFVHSY-AMPVNP---WTIAQCNYGEPFTAAVQKDNFYG 174

Query: 735 VQFHPEKSGATGLNIFENFL 794
           VQFHPE+SGA G  + +NFL
Sbjct: 175 VQFHPERSGAAGAKLLKNFL 194

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>P60595:HIS5_ECOLI Imidazole glycerol phosphate synthase subunit hisH - Escherichia|
           coli
          Length = 196

 Score =  145 bits (365), Expect = 8e-34
 Identities = 83/200 (41%), Positives = 116/200 (58%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V +LD G  N+ SV++AI   G+  +  R P+ +L AD+L  PGVG   +AMD +    +
Sbjct: 3   VVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVREREL 62

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            D ++      +P LGICLG+QLL   SEE+  V  LG+I   V +  +  GL +PH+GW
Sbjct: 63  FDLIKA---CTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKM-TDFGLPLPHMGW 118

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N +      +L QG  DG + YFVHSY A+P +    W    CNYGE F +++   N   
Sbjct: 119 NRVYPQAGNRLFQGIEDGAYFYFVHSY-AMPVNP---WTIAQCNYGEPFTAAVQKDNFYG 174

Query: 735 VQFHPEKSGATGLNIFENFL 794
           VQFHPE+SGA G  + +NFL
Sbjct: 175 VQFHPERSGAAGAKLLKNFL 194

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>P60596:HIS5_ECOL6 Imidazole glycerol phosphate synthase subunit hisH - Escherichia|
           coli O6
          Length = 196

 Score =  145 bits (365), Expect = 8e-34
 Identities = 83/200 (41%), Positives = 116/200 (58%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V +LD G  N+ SV++AI   G+  +  R P+ +L AD+L  PGVG   +AMD +    +
Sbjct: 3   VVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVREREL 62

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            D ++      +P LGICLG+QLL   SEE+  V  LG+I   V +  +  GL +PH+GW
Sbjct: 63  FDLIKA---CTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKM-TDFGLPLPHMGW 118

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N +      +L QG  DG + YFVHSY A+P +    W    CNYGE F +++   N   
Sbjct: 119 NRVYPQAGNRLFQGIEDGAYFYFVHSY-AMPVNP---WTIAQCNYGEPFTAAVQKDNFYG 174

Query: 735 VQFHPEKSGATGLNIFENFL 794
           VQFHPE+SGA G  + +NFL
Sbjct: 175 VQFHPERSGAAGAKLLKNFL 194

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>Q3M5W4:HIS5_ANAVT Imidazole glycerol phosphate synthase subunit hisH - Anabaena|
           variabilis (strain ATCC 29413 / PCC 7937)
          Length = 211

 Score =  145 bits (365), Expect = 8e-34
 Identities = 81/202 (40%), Positives = 118/202 (58%), Gaps = 2/202 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V ++DY  GN+ SV   +   G       S +++  AD ++ PGVGAF  A+  L    +
Sbjct: 4   VAVIDYEMGNLHSVCKGLEKAGATPIITHSHQELTKADAVILPGVGAFDPAVQSLRSRDL 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              +++ I   +PFLGICLGLQ+LF+SS E G   GLG+I G VRRF S  G+ +PH+GW
Sbjct: 64  EQPIKDTIASGKPFLGICLGLQILFESSAE-GTQPGLGIIKGKVRRFISEPGITIPHMGW 122

Query: 558 NALQITKDTQLL--QGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           N L++T+   +L         VYFVHSY+  P +      ++T +  ++  ++I+  N+ 
Sbjct: 123 NQLELTQPKSILWEHLPPQPWVYFVHSYYVDPVEPQVRAATVT-HGTQTVTAAIAHENLM 181

Query: 732 AVQFHPEKSGATGLNIFENFLS 797
           AVQFHPEKS   GL I  NF+S
Sbjct: 182 AVQFHPEKSSNIGLQILSNFVS 203

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>Q88R44:HIS5_PSEPK Imidazole glycerol phosphate synthase subunit hisH - Pseudomonas|
           putida (strain KT2440)
          Length = 212

 Score =  144 bits (364), Expect = 1e-33
 Identities = 86/208 (41%), Positives = 118/208 (56%), Gaps = 7/208 (3%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILA-ADRLVFPGVGAFGSAMDVLNRT 371
           TV ++DYG GN+ SV  A+ H+G     V S   ++  ADR+VFPGVGA    M  + R 
Sbjct: 3   TVAVIDYGMGNLHSVAKALEHVGAGKVLVTSDASVIREADRVVFPGVGAIRDCMAEIRRL 62

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEGL 536
           G    +RE +  DRPFLGIC+G+Q L + SEEN  V  +G+ PG VR F     +  E L
Sbjct: 63  GFDSLVRE-VSQDRPFLGICVGMQALLEHSEENAGVDCIGLFPGQVRFFGKDLQEEGEHL 121

Query: 537 IVPHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSI 713
            VPH+GWN +  T D  L     D    YFVHSY+   +      +    +YG  F +++
Sbjct: 122 KVPHMGWNEVSQTIDHPLWHDIPDRARFYFVHSYYI--NAGKPGQVVGRGHYGVDFAAAL 179

Query: 714 SMGNIQAVQFHPEKSGATGLNIFENFLS 797
           + G+  AVQFHPEKS   GL + +NF++
Sbjct: 180 ADGSRFAVQFHPEKSHTHGLQLLQNFIA 207

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>Q3AD50:HIS5_CARHZ Imidazole glycerol phosphate synthase subunit hisH -|
           Carboxydothermus hydrogenoformans (strain Z-2901 / DSM
           6008)
          Length = 199

 Score =  144 bits (363), Expect = 1e-33
 Identities = 82/197 (41%), Positives = 112/197 (56%), Gaps = 2/197 (1%)
 Frame = +3

Query: 204 LLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGMAD 383
           ++DY  GN+ SV  A+  LG+       P  IL  D +V PGVGAF  A+  L   G+  
Sbjct: 4   VVDYEMGNLLSVTKALEELGYKPSVTSDPRKILEEDLVVLPGVGAFRDAVRNLKEKGLFL 63

Query: 384 ALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGWNA 563
           AL+E   ++RP LGICLG+QL F  S E+G   GL +IPG V RF  +    +PH+GWN 
Sbjct: 64  ALKERASLNRPILGICLGMQLFFTKSYEDGEYEGLDLIPGEVVRFQKAPK--IPHMGWNN 121

Query: 564 LQITKDT--QLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQAV 737
           L +  DT  +L +     +VYFVHSY+A     +  ++     YGE F +++  G+I   
Sbjct: 122 L-VPVDTTHELFKNLPDYYVYFVHSYYA---QTDSRYVLAYTEYGEKFPAAVRRGSIIGF 177

Query: 738 QFHPEKSGATGLNIFEN 788
           QFHPEKSG  G  I +N
Sbjct: 178 QFHPEKSGPVGRQILKN 194

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>Q8DJN7:HIS6_SYNEL Imidazole glycerol phosphate synthase subunit hisF - Synechococcus|
            elongatus (Thermosynechococcus elongatus)
          Length = 281

 Score =  144 bits (362), Expect = 2e-33
 Identities = 106/321 (33%), Positives = 160/321 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR++ CLDV++       V KG  +          +R+ G PVELA  Y   GADE+ 
Sbjct: 3    LAKRILPCLDVKAGR-----VVKGVNF--------VNLRDAGDPVELAQAYNAAGADELV 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT           +++V+   +++VF+PLTVGGGI+           SL +  +  R
Sbjct: 50   FLDITATHE---ERNILIDVVYRTADQVFIPLTVGGGIQ-----------SLTMIKDLLR 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV   +             + Q S  +G Q +VV+ID RR    +PD+ 
Sbjct: 96   AGADKVSLNSAAVRQPDL------------VNQASDRFGAQCIVVAIDARREPDCAPDQP 143

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
            +                  +Q  V GGR++  + A   A  + + GAGE+L+  +D DG 
Sbjct: 144  R------------------WQVYVRGGREATGLDAVAWAVEMAKRGAGELLVTSMDADGT 185

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D++L + +++ V IPVIAS GAG  EH      +  A AAL A + H  ++ I  +
Sbjct: 186  QAGYDLELTRAIAERVEIPVIASGGAGTCEHIRAALVEGKAEAALLASLLHYGQLTIAQI 245

Query: 1746 KEHLVDAGVEVRMQ*SEMDQP 1808
            K +L    V VR Q   + QP
Sbjct: 246  KGYLHQHQVPVR-QAEPLPQP 265

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>Q316L4:HIS6_DESDG Imidazole glycerol phosphate synthase subunit hisF - Desulfovibrio|
            desulfuricans (strain G20)
          Length = 259

 Score =  144 bits (362), Expect = 2e-33
 Identities = 105/313 (33%), Positives = 154/313 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L+KR+I CLDVR     D  +TKG ++            ++G PVE A +YY  GADE+ 
Sbjct: 2    LSKRIIPCLDVR-----DGRLTKGIKFQGNV--------DIGDPVESARRYYEQGADEIV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            F +IT       G    L+++   +  +F+P +VGGGI    D             +   
Sbjct: 49   FYDITASHE---GRGIFLDIVEKVASSIFIPFSVGGGINTVDD-----------MRDALN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GA+K+S+ S AV   +   +   +            +G+QA+V+ +D +RV   +P E 
Sbjct: 95   AGAEKVSVNSGAVKDPDIISKGAAR------------FGSQAIVLGMDVKRV---APTEA 139

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                       P G     Y+  + GGR    + A + AK  E LGAGEI +N ID DG 
Sbjct: 140  I----------PSG-----YEIVIHGGRKHMGMDALDWAKTAEVLGAGEICVNSIDADGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+++ L +M+SDAV IPVIAS GAG   H  +   K  ASAAL A I H  E  I  +
Sbjct: 185  KDGYELTLTRMISDAVQIPVIASGGAGHPAHMYDALTKGGASAALIASIVHYGEYTIPDL 244

Query: 1746 KEHLVDAGVEVRM 1784
            K+ +   G ++R+
Sbjct: 245  KKQIQAMGCKMRL 257

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>Q5WDI2:HIS6_BACSK Imidazole glycerol phosphate synthase subunit hisF - Bacillus clausii|
            (strain KSM-K16)
          Length = 252

 Score =  144 bits (362), Expect = 2e-33
 Identities = 106/312 (33%), Positives = 151/312 (48%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLDV+        V KG Q+          +R+ G PVELA+ Y  +GADE+ 
Sbjct: 2    LAKRIIPCLDVKEGR-----VVKGTQF--------LSLRDAGDPVELAAFYDKEGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I+       G   M++V+R  +  + +P TVGGGI    D                R
Sbjct: 49   FLDISASHE---GRETMVDVVREVAATLAIPFTVGGGINTLAD-----------IRRILR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + A+    A+++ G              +G+Q +VV+ID +          
Sbjct: 95   AGADKVSINTAALLRP-AFIREGAD-----------YFGSQCIVVAIDAK---------- 132

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                          +    ++    GGR      A + AK    LGAGE+L+  +D DG 
Sbjct: 133  ------------FDQALGTWRVYTHGGRKQTNWLATDWAKEAVRLGAGELLVTSMDQDGA 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L+K +++  T+PVIAS GAGA   F +VF+   A AALAA IFH KE  I  V
Sbjct: 181  KTGFDLPLLKAINEVATVPVIASGGAGAANDFVDVFKYNYADAALAASIFHYKETSIQEV 240

Query: 1746 KEHLVDAGVEVR 1781
            K  L + G  +R
Sbjct: 241  KARLREEGECIR 252

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>Q8G4S6:HIS5_BIFLO Imidazole glycerol phosphate synthase subunit hisH -|
           Bifidobacterium longum
          Length = 215

 Score =  144 bits (362), Expect = 2e-33
 Identities = 80/214 (37%), Positives = 123/214 (57%), Gaps = 13/214 (6%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTG 374
           T  + DYG GNVRS+  A+ +LG +          L AD LV PGVGAF + M+ L +  
Sbjct: 3   TAVVFDYGFGNVRSMVRALANLGVDTTLTSDYRQSLEADGLVVPGVGAFAACMEGLKKVD 62

Query: 375 MADALREYIRMDRPFLGICLGLQLLFDSSEENGP-VSGLGVIPGVVRRFDSSEGLIVPHI 551
               + + IR  RP LG+C+G Q++F+   E+G   +G+G+I G V   D+    +VPH+
Sbjct: 63  GDRVIYDRIRAGRPVLGVCVGEQIMFEHGLEHGAHAAGIGLIGGSVNLLDAD---VVPHM 119

Query: 552 GWNALQITKDTQLLQGADGQHVYFVHSYHAL---PSDANKDWISLT--------CNYGES 698
           GW+ ++   D+ LL G + +  YFVHSY A+   P+D ++  I L+        C+YG S
Sbjct: 120 GWDTIETAPDSVLLNGVENERFYFVHSYAAMEVKPADTSRFDIDLSDSPERVSWCSYGRS 179

Query: 699 -FISSISMGNIQAVQFHPEKSGATGLNIFENFLS 797
            F+++   G + A QFHPEKSG  G  + +N+++
Sbjct: 180 RFVAAYEHGPLSATQFHPEKSGDAGSQLLKNWIA 213

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>O34565:HIS5_BACSU Imidazole glycerol phosphate synthase subunit hisH - Bacillus|
           subtilis
          Length = 212

 Score =  143 bits (361), Expect = 2e-33
 Identities = 76/202 (37%), Positives = 110/202 (54%), Gaps = 4/202 (1%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++DYG GN+ SV  A+  +G        PE++  AD  + PGVG+FG AMD L  T +
Sbjct: 2   IGVIDYGMGNLYSVSKALERVGVPYFVSEKPEELKEADAFILPGVGSFGDAMDNLGYTKL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF----DSSEGLIVP 545
              + + +   R  LGICLG+QLLF+ SEENG  SGLG++ G   R     +    L VP
Sbjct: 62  DQLIHDMVSEGRLLLGICLGMQLLFEESEENGTASGLGLLKGKAVRLKAEDEKGNKLKVP 121

Query: 546 HIGWNALQITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGN 725
           H+GWN L    ++ LL   +  + YFVHSY+    + N   +  + +YG    + +   N
Sbjct: 122 HMGWNRLSFHNESPLLTKTEQGYAYFVHSYYIDGMEENA--LLASADYGVRVPAVVGKRN 179

Query: 726 IQAVQFHPEKSGATGLNIFENF 791
           +   QFHPEKS   G++I   F
Sbjct: 180 VFGAQFHPEKSSTVGMSILTQF 201

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>Q2RNA5:HIS5_RHORT Imidazole glycerol phosphate synthase subunit hisH - Rhodospirillum|
           rubrum (strain ATCC 11170 / NCIB 8255)
          Length = 214

 Score =  143 bits (360), Expect = 3e-33
 Identities = 91/210 (43%), Positives = 115/210 (54%), Gaps = 11/210 (5%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRH------LGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDV 359
           V L+DYG+GN+RS   A+        +   I   R  E +L ADR+V PGVGAF +    
Sbjct: 3   VALIDYGSGNLRSAAKALERAARDGGVAAEIVVTRDVEGVLGADRVVLPGVGAFANCRRG 62

Query: 360 LNRT-GMADALREYIRMD-RPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSE- 530
           L    GM +AL E   +  RPFLGIC+G+QLL D   E G   GLG I G V     ++ 
Sbjct: 63  LQGIDGMVEALAEVALVRARPFLGICVGMQLLADEGVEYGRHPGLGWIGGTVEAISPADP 122

Query: 531 GLIVPHIGWNALQITKDTQ-LLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYGESFI 704
            L +PH+GWN+L    D+  LL G + G HVYFVHSYH  P+D      S+   YG    
Sbjct: 123 ALKIPHMGWNSLDFQADSHALLAGIEPGTHVYFVHSYHFRPADPATRLASV--EYGGPLT 180

Query: 705 SSISMGNIQAVQFHPEKSGATGLNIFENFL 794
           + I   N+   QFHPEKS A GL +  NFL
Sbjct: 181 AMIGRENLVGTQFHPEKSQAAGLRLIANFL 210

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>Q67KI0:HIS6_SYMTH Imidazole glycerol phosphate synthase subunit hisF - Symbiobacterium|
            thermophilum
          Length = 254

 Score =  142 bits (359), Expect = 4e-33
 Identities = 110/312 (35%), Positives = 155/312 (49%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLD+R     D  V K  Q+ +    +       G PV LA++Y   GADE+ 
Sbjct: 3    LAKRIIPCLDIR-----DGRVVKNVQFHLNTWDA-------GDPVALAAEYDRQGADEIV 50

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I    A   G    L+VL  A+E+VFVPLT+GGG+           S++E    Y R
Sbjct: 51   FLDIN---ASWEGRSATLDVLSRAAEQVFVPLTIGGGV-----------SAVEHVKAYLR 96

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ + AV   +             +++I+ ++G+  +VV+ID +R         
Sbjct: 97   AGADKVSVNTAAVQRPDL------------IDEIADLFGSSTLVVAIDCKR--------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E  W +  + GGR    I A   A+     GAGE+L+  +D DG 
Sbjct: 136  -------------RPEGGW-EVYLHGGRTPTGIDAVAWAEEAARRGAGELLVTSMDADGT 181

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L + ++DAV +PVIAS GAG+ E   EV     A AALAA IFH     +  V
Sbjct: 182  RQGYDIALHQALADAVGVPVIASGGAGSPEDILEVLTVGRADAALAASIFHSGRHTVGEV 241

Query: 1746 KEHLVDAGVEVR 1781
            K  L + GV VR
Sbjct: 242  KAFLRERGVLVR 253

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>Q3SEU6:HIS5_THIDA Imidazole glycerol phosphate synthase subunit hisH - Thiobacillus|
           denitrificans (strain ATCC 25259)
          Length = 228

 Score =  142 bits (359), Expect = 4e-33
 Identities = 88/212 (41%), Positives = 122/212 (57%), Gaps = 10/212 (4%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDV--RSPEDILAADRLVFPGVGAFGSAMDVLNRT 371
           + ++DYG GN+RSV  AI H+  +   V   SP+ I  A R+VFPG GA    M  ++  
Sbjct: 5   IAVVDYGMGNLRSVSKAIEHVAPSATVVVTSSPDVIAEAGRVVFPGQGAARDCMREIDAR 64

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-------DSSE 530
           G+ +A+    R  +PFLGIC+G+Q+LF+ SEE G  + LG++PG V+RF       D   
Sbjct: 65  GLREAIATAAR-SKPFLGICMGMQVLFEHSEE-GDTACLGILPGNVQRFPHEAMHDDRGN 122

Query: 531 GLIVPHIGWNALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFIS 707
            L VPH+GWN +       L  G  DG+  YFVHSY   P+    D I+   +Y   F  
Sbjct: 123 KLKVPHMGWNNVHQGAPHPLWSGIEDGERFYFVHSYFVQPT--TPDLIAGFSHYPFPFTC 180

Query: 708 SISMGNIQAVQFHPEKSGATGLNIFENFLSPN 803
           +++ GNI AVQFHPEKS   GL +  NF++ N
Sbjct: 181 AVASGNIFAVQFHPEKSQNAGLTLLGNFVTWN 212

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>Q87UG1:HIS5_PSESM Imidazole glycerol phosphate synthase subunit hisH - Pseudomonas|
           syringae pv. tomato
          Length = 212

 Score =  142 bits (359), Expect = 4e-33
 Identities = 85/206 (41%), Positives = 118/206 (57%), Gaps = 7/206 (3%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILA-ADRLVFPGVGAFGSAMDVLNRT 371
           TV ++DYG GN+ SV  A+ H+G     + S   ++  ADR+VFPGVGA    M  + R 
Sbjct: 3   TVAVIDYGMGNLHSVAKALEHVGAGRVLITSDAKVIREADRVVFPGVGAIRDCMAEIRRL 62

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEGL 536
           G    +RE +  DRPFLGIC+G+Q L D SEE+G V  +G+ PG V+ F     +  E L
Sbjct: 63  GFDSLVRE-VSQDRPFLGICVGMQALLDRSEESGGVDCIGLFPGQVKFFGKNLHEEGEHL 121

Query: 537 IVPHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSI 713
            VPH+GWN +    D  L     D    YFVHS++     AN+  +    +YG  F +++
Sbjct: 122 KVPHMGWNQVTQAVDHPLWHDIPDLARFYFVHSFYI--DAANQRQVVGRGHYGLDFAAAL 179

Query: 714 SMGNIQAVQFHPEKSGATGLNIFENF 791
           + G+  AVQFHPEKS   GL + +NF
Sbjct: 180 ADGSRFAVQFHPEKSHTHGLQLLQNF 205

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>Q48C78:HIS5_PSE14 Imidazole glycerol phosphate synthase subunit hisH - Pseudomonas|
           syringae pv. phaseolicola (strain 1448A / Race 6)
          Length = 212

 Score =  142 bits (359), Expect = 4e-33
 Identities = 85/206 (41%), Positives = 118/206 (57%), Gaps = 7/206 (3%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILA-ADRLVFPGVGAFGSAMDVLNRT 371
           TV ++DYG GN+ SV  A+ H+G     + S   ++  ADR+VFPGVGA    M  + R 
Sbjct: 3   TVAVIDYGMGNLHSVAKALEHVGAGRVLITSDAKVIREADRVVFPGVGAIRDCMAEIRRL 62

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEGL 536
           G    +RE +  DRPFLGIC+G+Q L D SEE+G V  +G+ PG V+ F     +  E L
Sbjct: 63  GFDSLVRE-VSQDRPFLGICVGMQALLDRSEESGGVDCIGLFPGQVKFFGKDLYEEGEHL 121

Query: 537 IVPHIGWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSI 713
            VPH+GWN +    D  L     D    YFVHS++     AN+  +    +YG  F +++
Sbjct: 122 KVPHMGWNQVAQAVDHPLWHDIPDLARFYFVHSFYI--DAANQRQVVGRGHYGLDFAAAL 179

Query: 714 SMGNIQAVQFHPEKSGATGLNIFENF 791
           + G+  AVQFHPEKS   GL + +NF
Sbjct: 180 ADGSRFAVQFHPEKSHTHGLQLLQNF 205

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>Q9RDX3:HIS5_LEGPN Imidazole glycerol phosphate synthase subunit hisH - Legionella|
           pneumophila
          Length = 213

 Score =  142 bits (359), Expect = 4e-33
 Identities = 83/211 (39%), Positives = 122/211 (57%), Gaps = 10/211 (4%)
 Frame = +3

Query: 192 NTVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRT 371
           ++V+++DYG GN+ SV  A ++   ++  V +PE+I++ADRLV PGVGAF   M  L   
Sbjct: 2   SSVSIVDYGVGNLLSVARAFQYFDASVNLVSTPEEIMSADRLVLPGVGAFEDGMKGLTTL 61

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSS--EGLI-- 539
              + ++++ R  +PFLGICLG+Q++   S E G   GL +I G V    S   +G +  
Sbjct: 62  NFIEPIKQFARSGKPFLGICLGMQMMLSRSTEFGQHEGLDLIAGEVVSVPSHGVDGQLHK 121

Query: 540 VPHIGWNALQITKD------TQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESF 701
           +PHIGWN L  T +      T L        VYFVHS+ A+PS+  K  ++ T   G++ 
Sbjct: 122 IPHIGWNELVSTSEGEDWCHTILKNIPLNSSVYFVHSFMAMPSNPKKR-LADTLYDGQAI 180

Query: 702 ISSISMGNIQAVQFHPEKSGATGLNIFENFL 794
            + I   N+   QFHPEKSG  GL+I + FL
Sbjct: 181 SAVIKDENMYGCQFHPEKSGEVGLSIIQQFL 211

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>Q5ZXI1:HIS51_LEGPH Imidazole glycerol phosphate synthase subunit hisH 1 - Legionella|
           pneumophila subsp. pneumophila (strain Philadelphia 1 /
           ATCC 33152 / DSM 7513)
          Length = 213

 Score =  142 bits (359), Expect = 4e-33
 Identities = 83/211 (39%), Positives = 122/211 (57%), Gaps = 10/211 (4%)
 Frame = +3

Query: 192 NTVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRT 371
           ++V+++DYG GN+ SV  A ++   ++  V +PE+I++ADRLV PGVGAF   M  L   
Sbjct: 2   SSVSIVDYGVGNLLSVARAFQYFDASVNLVSTPEEIMSADRLVLPGVGAFEDGMKGLTTL 61

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSS--EGLI-- 539
              + ++++ R  +PFLGICLG+Q++   S E G   GL +I G V    S   +G +  
Sbjct: 62  NFIEPIKQFARSGKPFLGICLGMQMMLSRSTEFGQHEGLDLIAGEVVSVPSHGVDGQLHK 121

Query: 540 VPHIGWNALQITKD------TQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESF 701
           +PHIGWN L  T +      T L        VYFVHS+ A+PS+  K  ++ T   G++ 
Sbjct: 122 IPHIGWNELVSTSEGEDWCHTILKNIPLNSSVYFVHSFMAMPSNPKKR-LADTLYDGQAI 180

Query: 702 ISSISMGNIQAVQFHPEKSGATGLNIFENFL 794
            + I   N+   QFHPEKSG  GL+I + FL
Sbjct: 181 SAVIKDENMYGCQFHPEKSGEVGLSIIQQFL 211

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>Q5X6Z7:HIS51_LEGPA Imidazole glycerol phosphate synthase subunit hisH 1 - Legionella|
           pneumophila (strain Paris)
          Length = 213

 Score =  142 bits (359), Expect = 4e-33
 Identities = 83/211 (39%), Positives = 122/211 (57%), Gaps = 10/211 (4%)
 Frame = +3

Query: 192 NTVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRT 371
           ++V+++DYG GN+ SV  A ++   ++  V +PE+I++ADRLV PGVGAF   M  L   
Sbjct: 2   SSVSIVDYGVGNLLSVARAFQYFDASVNLVSTPEEIMSADRLVLPGVGAFEDGMKGLTTL 61

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSS--EGLI-- 539
              + ++++ R  +PFLGICLG+Q++   S E G   GL +I G V    S   +G +  
Sbjct: 62  NFIEPIKQFARSGKPFLGICLGMQMMLSRSTEFGQHEGLDLIAGEVVSVPSHGVDGQLHK 121

Query: 540 VPHIGWNALQITKD------TQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESF 701
           +PHIGWN L  T +      T L        VYFVHS+ A+PS+  K  ++ T   G++ 
Sbjct: 122 IPHIGWNELVSTSEGEDWCHTILKNIPLNSSVYFVHSFMAMPSNPKKR-LADTLYDGQAI 180

Query: 702 ISSISMGNIQAVQFHPEKSGATGLNIFENFL 794
            + I   N+   QFHPEKSG  GL+I + FL
Sbjct: 181 SAVIKDENMYGCQFHPEKSGEVGLSIIQQFL 211

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>Q7V8Q8:HIS61_PROMM Imidazole glycerol phosphate synthase subunit hisF1 - Prochlorococcus|
            marinus (strain MIT 9313)
          Length = 256

 Score =  142 bits (358), Expect = 5e-33
 Identities = 106/312 (33%), Positives = 152/312 (48%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            +A R+I CLDV      D  V KG  +          +R+ G PVELA +Y   GADE+ 
Sbjct: 2    VALRLIPCLDV-----ADGRVVKGVNF--------VGLRDAGDPVELACRYSQAGADELV 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+I        G   ++ ++R  +E V +P TVGGGI           SSL+  +E  R
Sbjct: 49   FLDIAASHE---GRATLVALVRRTAEAVTIPFTVGGGI-----------SSLDGITELLR 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+S+ S AV   +   Q   +            +G Q +VV+ID RR         
Sbjct: 95   AGADKVSLNSSAVRDPDLVAQGADR------------FGCQCIVVAIDARR--------- 133

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E + +   V GGR +  + A   A+   ELGAGEILL  +D DG 
Sbjct: 134  -------------RPECSGWDVFVKGGRQNTGLDAVSWARQAAELGAGEILLTSMDGDGT 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D++L + V +AV +PVIAS GAG ++H +E F    ASAAL A + H   + +  +
Sbjct: 181  QAGYDLELTQAVVEAVPVPVIASGGAGCLDHIAEAFTIGKASAALLASLLHDGVLSVEQI 240

Query: 1746 KEHLVDAGVEVR 1781
            K  L+  G+ +R
Sbjct: 241  KTDLLMRGLSIR 252

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>Q8PLG8:HIS5_XANAC Imidazole glycerol phosphate synthase subunit hisH - Xanthomonas|
           axonopodis pv. citri
          Length = 200

 Score =  142 bits (358), Expect = 5e-33
 Identities = 84/200 (42%), Positives = 113/200 (56%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V L+D G  N+ SVR A+  LG + R VR    +  A R++ PGVGA   AM  L   G+
Sbjct: 4   VALIDAGGANLGSVRYALERLGVDARLVRDAAGLQGAQRVILPGVGAAPEAMSRLRAQGL 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + LRE   +  P +GICLG+QLLF+ SEE G V  LG++PG+VR    + G+ +PH+GW
Sbjct: 64  VEPLRE---LQVPLIGICLGMQLLFEHSEE-GDVECLGLLPGIVRHMTPALGIRIPHMGW 119

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L   +D+ LL G  +    YFVH Y A P  A+       C++G  F + +  G    
Sbjct: 120 NQLVPMRDSALLAGLPERASAYFVHGY-AAPVTAD---TVAACDHGGLFTAVVQNGLRCG 175

Query: 735 VQFHPEKSGATGLNIFENFL 794
            QFHPE+S  TG  I  NFL
Sbjct: 176 AQFHPERSAETGARILRNFL 195

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>P58237:HIS5_ECO57 Imidazole glycerol phosphate synthase subunit hisH - Escherichia|
           coli O157:H7
          Length = 196

 Score =  142 bits (358), Expect = 5e-33
 Identities = 82/200 (41%), Positives = 115/200 (57%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V +L  G  N+ SV++AI   G+  +  R P+ +L AD+L  PGVG   +AMD +    +
Sbjct: 3   VVILGTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVREREL 62

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            D ++      +P LGICLG+QLL   SEE+  V  LG+I   V +  +  GL +PH+GW
Sbjct: 63  FDLIKA---CTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKM-TDFGLPLPHMGW 118

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N +      +L QG  DG + YFVHSY A+P +    W    CNYGE F +++   N   
Sbjct: 119 NRVYPQAGNRLFQGIEDGAYFYFVHSY-AMPVNP---WTIAQCNYGEPFTAAVQKDNFYG 174

Query: 735 VQFHPEKSGATGLNIFENFL 794
           VQFHPE+SGA G  + +NFL
Sbjct: 175 VQFHPERSGAAGAKLLKNFL 194

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>Q9ZGM1:HIS5_LEPBO Imidazole glycerol phosphate synthase subunit hisH - Leptospira|
           borgpetersenii
          Length = 204

 Score =  142 bits (357), Expect = 7e-33
 Identities = 78/205 (38%), Positives = 125/205 (60%), Gaps = 5/205 (2%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + +LDYG GN+++  N ++ L F+ + V++ +++   ++++ PGVG+F S M+ L  +G+
Sbjct: 2   IGILDYGVGNLKAFANVLKGLNFHHQIVKTEQELKGCEKIIMPGVGSFDSVMNKLIESGI 61

Query: 378 ADALREYIRMDR-PFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFD---SSEGLIVP 545
            D L + I   + P LG+C+G+Q+L  SSEE G  SGLG I G V++F+   S   L +P
Sbjct: 62  RDVLSDLIINKKIPILGVCVGMQILASSSEE-GSKSGLGWIRGRVKKFNFDRSDFSLTIP 120

Query: 546 HIGWNALQITKDTQLLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMG 722
            IGWN +  TK+  LL+  +     YF+HSY+ +  +  KD I++  NYG  F  +++  
Sbjct: 121 QIGWNEVNSTKENTLLKNLEKNPRFYFLHSYY-IECEDKKDVIAI-ANYGGDFTCAVNRE 178

Query: 723 NIQAVQFHPEKSGATGLNIFENFLS 797
           NI   QFHPEKS   G+ +  NF S
Sbjct: 179 NIYGTQFHPEKSHHNGVALIRNFAS 203

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>Q9HU42:HIS51_PSEAE Imidazole glycerol phosphate synthase subunit hisH 1 - Pseudomonas|
           aeruginosa
          Length = 213

 Score =  142 bits (357), Expect = 7e-33
 Identities = 86/208 (41%), Positives = 119/208 (57%), Gaps = 7/208 (3%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILA-ADRLVFPGVGAFGSAMDVLNRT 371
           TV ++DYG GN+ SV  A+ H+G     V S   ++  ADR+VFPGVGA    M  + R 
Sbjct: 4   TVAVIDYGMGNLHSVAKALEHVGAGRVLVSSDAAVIREADRVVFPGVGAIRDCMAEIRRL 63

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-----DSSEGL 536
           G  DAL   +  DRPFLGIC+G+Q L + SEEN  V  +G+ PG VR F     ++ E L
Sbjct: 64  GF-DALVREVSQDRPFLGICVGMQALLERSEENDGVDCIGLFPGQVRFFGKDLHEAGEHL 122

Query: 537 IVPHIGWNAL-QITKDTQLLQGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSI 713
            VPH+GWN + Q  +     +  D    YFVHSY+      N   +    +YG  F +++
Sbjct: 123 KVPHMGWNQVSQAVEHPLWHEIPDQARFYFVHSYYI--EAGNPRQVVGHGHYGVDFAAAL 180

Query: 714 SMGNIQAVQFHPEKSGATGLNIFENFLS 797
           + G+  AVQFHPEKS   GL + +NF++
Sbjct: 181 AEGSRFAVQFHPEKSHTHGLQLLQNFVA 208

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>Q98CT1:HIS6_RHILO Imidazole glycerol phosphate synthase subunit hisF - Rhizobium loti|
            (Mesorhizobium loti)
          Length = 263

 Score =  141 bits (356), Expect = 9e-33
 Identities = 111/325 (34%), Positives = 154/325 (47%), Gaps = 4/325 (1%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L  RVI CLDV+     D  V KG  +         ++ + G PVE A  Y   GADE+ 
Sbjct: 2    LKARVIPCLDVK-----DGRVVKGVNF--------VDLIDAGDPVEAAKAYDAAGADELC 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       + +V+   +E+ F+PLTVGGG+R   D             +   
Sbjct: 49   FLDIT---ASSDNRETIFDVIARTAEQCFMPLTVGGGVRQVAD-----------IRKLLL 94

Query: 1206 SGADKISIGSDAV----FAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKS 1373
            +GADK+SI + AV    F AEA                +  +GNQ +VV+ID ++V    
Sbjct: 95   AGADKVSINTAAVKNPDFVAEA----------------ADKFGNQCIVVAIDAKKV---- 134

Query: 1374 PDEVQFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCID 1553
                             GE   W +    GGR+   I A E A+ + + GAGEILL  +D
Sbjct: 135  --------------SGAGEADRW-EIFTHGGREKTGIDAVEFARKMVDRGAGEILLTSMD 179

Query: 1554 CDGQGGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVP 1733
             DG   G+DI L + ++DAV  P+IAS G G ++H  E     +A A LAA IFH     
Sbjct: 180  RDGTKAGYDIALTRAIADAVRAPIIASGGVGTLDHLVEGIRDGHAGAVLAASIFHFGTYT 239

Query: 1734 ILAVKEHLVDAGVEVRMQ*SEMDQP 1808
            I   K H+  AG+ +R+  S  D+P
Sbjct: 240  IAQAKAHMAAAGLPMRLD-SSGDRP 263

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>Q7VGZ1:HIS6_HELHP Imidazole glycerol phosphate synthase subunit hisF - Helicobacter|
            hepaticus
          Length = 251

 Score =  141 bits (356), Expect = 9e-33
 Identities = 106/313 (33%), Positives = 160/313 (51%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            LAKR+I CLD+    NG  VV   +   ++D          G PVE+A +Y  +GADE+ 
Sbjct: 3    LAKRIIPCLDI----NGGRVVKGVNFIGLQD---------AGDPVEIARRYNDEGADEIV 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
             L+IT   ++    + M+EV++  +++VF+P +VGGGIR           SLE  S    
Sbjct: 50   LLDITA--SYEQRGI-MIEVVKNIAKEVFIPFSVGGGIR-----------SLEDMSALLN 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +G DKISI S A+                 +++ ++ +G+Q +VV++D ++V   S    
Sbjct: 96   AGCDKISINSAAI------------RNPQLIDESAKRFGSQCIVVAVDVKKVSQNS---- 139

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               +   ++GGR        E        GAGEILL  ID DG 
Sbjct: 140  -------------------WNVYINGGRVDSGKDMLEWINEACARGAGEILLTSIDTDGT 180

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
             GG+D  +I+ V  ++ +P+IAS GAG++E F++VF    A AALAA +FH KE+ I  +
Sbjct: 181  KGGYDKAMIEAVK-SINVPIIASGGAGSMEDFADVFVH-GADAALAASVFHYKEIEIKML 238

Query: 1746 KEHLVDAGVEVRM 1784
            K +L D GV VR+
Sbjct: 239  KTYLQDKGVPVRI 251

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>Q9TLQ8:HIS5_CYACA Imidazole glycerol phosphate synthase subunit hisH - Cyanidium|
           caldarium
          Length = 214

 Score =  141 bits (356), Expect = 9e-33
 Identities = 88/214 (41%), Positives = 122/214 (57%), Gaps = 14/214 (6%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDIL--AADRLVFPGVGAFGSAMDVLNRT 371
           + +++ G GN+ SV NAI ++GFN   + + +D++  A   LV PGVG+F  A+D L + 
Sbjct: 4   IGIINCGMGNLHSVSNAISNIGFNPVIINASKDLVSFACSALVLPGVGSFDLAIDRLEKK 63

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHI 551
            + + ++ +I+ DRPF+GICLGLQLLF+ S+E G   GL +  G V +F  S    VPH+
Sbjct: 64  NLIEPVKLWIQEDRPFVGICLGLQLLFEGSDE-GSKPGLKIFNGYVSQFKHSLVKKVPHM 122

Query: 552 GWNALQITKDTQL-----------LQGADGQHVYFVHSYHALPSDA-NKDWISLTCNYGE 695
           GWN L   +   +           LQ       YFVHSY+  P D    +  SLT    +
Sbjct: 123 GWNKLYFNRFNTIDNLVPHYFHYDLQ----PWAYFVHSYYIEPKDCYTFNTTSLTFYGKQ 178

Query: 696 SFISSISMGNIQAVQFHPEKSGATGLNIFENFLS 797
             +SSIS  NI A QFHPEKSG  GL I + FLS
Sbjct: 179 KIVSSISYNNILATQFHPEKSGLFGLFILKRFLS 212

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>Q92TB3:HIS6_RHIME Imidazole glycerol phosphate synthase subunit hisF - Rhizobium|
            meliloti (Sinorhizobium meliloti)
          Length = 258

 Score =  141 bits (355), Expect = 1e-32
 Identities = 107/313 (34%), Positives = 149/313 (47%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L  RVI CLDV+     D  V KG  +         ++ + G PVE A  Y   GADE+ 
Sbjct: 3    LKARVIPCLDVK-----DGRVVKGVNF--------VDLIDAGDPVEAARAYDAAGADELC 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       + +V+   +E+ F+PLTVGGG+R   D             +   
Sbjct: 50   FLDIT---ASSDNRETIFDVVARTAEQCFMPLTVGGGVRQVAD-----------IRKLLL 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV   E   +   K            +G+Q +VV+ID ++V  +     
Sbjct: 96   AGADKVSINTAAVKNPEFVAEAADK------------FGDQCIVVAIDAKKVSAQ----- 138

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W +    GGR    I A E A+ V +LGAGEILL  +D DG 
Sbjct: 139  -------------GEADRW-EIFTHGGRQPTGIDAIEFARKVVDLGAGEILLTSMDRDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+DI L + ++DAV  PVIAS G G ++H  E     +A+A LAA IFH     I   
Sbjct: 185  KSGYDISLTRAIADAVRAPVIASGGVGTLDHMVEGIRDGHATAVLAASIFHFGTYSIGEA 244

Query: 1746 KEHLVDAGVEVRM 1784
            K H+   G+ +R+
Sbjct: 245  KRHMAKHGIAMRL 257

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>P26721:HIS6_AZOBR Imidazole glycerol phosphate synthase subunit hisF - Azospirillum|
            brasilense
          Length = 261

 Score =  141 bits (355), Expect = 1e-32
 Identities = 106/312 (33%), Positives = 152/312 (48%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L  RVI CLDV+     D  V KG  +         ++ + G PVE A  Y  +GADE++
Sbjct: 2    LKMRVIPCLDVK-----DGRVVKGVNF--------VDLIDAGDPVEQARVYDREGADELT 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT           + +V+R  +E+VF+PLTVGGG+R   D             +   
Sbjct: 49   FLDITASHE---NRDTIYDVVRRTAEQVFMPLTVGGGVRTVDD-----------IRKLLL 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + A+   E             +++ +  +G Q +VV+ID ++V        
Sbjct: 95   AGADKVSINTAAIHRPEF------------VQEAAEKFGAQCIVVAIDAKQV-------- 134

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                           E   ++    GGR +  I A E AK +E  GAGEILL  +D DG 
Sbjct: 135  ---------------EPGRWEIFTHGGRKATGIDAIEWAKRMESYGAGEILLTSMDRDGT 179

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              GFD+ L + V+D + IPVIAS G G ++H  E   + +A+A LAA IFH     I   
Sbjct: 180  KSGFDLALTRKVADGLRIPVIASGGVGTLDHLVEGIREGHATAVLAASIFHFGTYTIGQA 239

Query: 1746 KEHLVDAGVEVR 1781
            K  L +AG+ VR
Sbjct: 240  KAALAEAGIPVR 251

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>Q4FNT7:HIS6_PELUB Imidazole glycerol phosphate synthase subunit hisF - Pelagibacter|
            ubique
          Length = 251

 Score =  140 bits (353), Expect = 2e-32
 Identities = 105/313 (33%), Positives = 157/313 (50%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L  R+I CLDV+   NG +V  KG  +         ++++ G PVE A  Y   GADE+ 
Sbjct: 2    LKNRIIPCLDVK---NGRVV--KGINF--------VDLKDAGDPVEQAKIYSDGGADEIC 48

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT  +        + +V+   S+K FVPLTVGGG+R   D            ++   
Sbjct: 49   FLDITASKE---NRDTIYDVVERTSKKCFVPLTVGGGVRGVED-----------INKLLN 94

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
             GADK+SI + AV + E  +++            S+ +G+Q +VV+ID +    K+ D+ 
Sbjct: 95   CGADKVSINTAAVQSPEMIIES------------SKKFGSQCIVVAIDAK----KNGDK- 137

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                               ++    GGR++  I A E AK +E+ GAGE+L+  +D DG 
Sbjct: 138  -------------------WEVFTHGGRNNTNIDAIEFAKKMEDNGAGELLVTSMDRDGT 178

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D DL+  +S  V IP+IAS G G ++H  +     NASA LAA IFH     I   
Sbjct: 179  QIGYDNDLMFKISSTVNIPIIASGGVGNLDHLVDGIRLGNASAVLAASIFHYGTHSINEA 238

Query: 1746 KEHLVDAGVEVRM 1784
            K++L   G+ VR+
Sbjct: 239  KQYLNSKGIPVRI 251

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>Q9KSX0:HIS5_VIBCH Imidazole glycerol phosphate synthase subunit hisH - Vibrio|
           cholerae
          Length = 203

 Score =  140 bits (353), Expect = 2e-32
 Identities = 80/205 (39%), Positives = 117/205 (57%), Gaps = 6/205 (2%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V ++D G  N+ SV+ AI  LG+ +   R P+ +LAAD+L  PGVG    AM  L    +
Sbjct: 5   VVIIDTGCANISSVKFAIERLGYAVTISRDPQVVLAADKLFLPGVGTASEAMKNLTERDL 64

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGP-----VSGLGVIPGVVRRFDSSEGLIV 542
            + ++   R+++P LGICLG+QLL   SEE G      V  LG++ G VR   + + L +
Sbjct: 65  IELVK---RVEKPLLGICLGMQLLGKLSEEKGQKADEIVQCLGLVDGEVRLLQTGD-LPL 120

Query: 543 PHIGWNALQITKDTQLLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISM 719
           PH+GWN +Q+ +   L  G +   + YFVHS+ A+P     D+    C YG+ F ++I  
Sbjct: 121 PHMGWNTVQVKEGHPLFNGIEPDAYFYFVHSF-AMPVG---DYTIAQCEYGQPFSAAIQA 176

Query: 720 GNIQAVQFHPEKSGATGLNIFENFL 794
           GN   VQFHPE+S   G  + +NFL
Sbjct: 177 GNYYGVQFHPERSSKAGARLIQNFL 201

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>Q5X5X2:HIS52_LEGPA Imidazole glycerol phosphate synthase subunit hisH 2 - Legionella|
           pneumophila (strain Paris)
          Length = 199

 Score =  140 bits (353), Expect = 2e-32
 Identities = 81/205 (39%), Positives = 113/205 (55%), Gaps = 1/205 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + ++D    N+ S+ NA+  LG +       E+I  A  ++ PGVG   S M  L + G+
Sbjct: 2   IAVIDVSGNNLTSLTNALIRLGGHFALTHDAEEIQKASHVILPGVGTARSGMTALQQNGL 61

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            D LR    + +P LGICLG+QLL + SEE+  +  LG+IPGV     +     VPH+GW
Sbjct: 62  IDVLRT---LTQPLLGICLGMQLLLEYSEEDD-IPCLGLIPGVAELLKAERNHPVPHMGW 117

Query: 558 NALQITKDTQLLQGADGQ-HVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L   K + L QG +   +VYFVHSY AL +D   D+    C Y E F + +  GN   
Sbjct: 118 NNLHWQKTSSLQQGLNNSDYVYFVHSY-ALKAD---DYALARCQYHEEFTAVVKKGNFYG 173

Query: 735 VQFHPEKSGATGLNIFENFLSPNSS 809
           +QFHPEKS   G+ +  NFLS  S+
Sbjct: 174 MQFHPEKSADVGMVLLNNFLSLEST 198

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>Q5JFV0:HIS5_PYRKO Imidazole glycerol phosphate synthase subunit hisH - Pyrococcus|
           kodakaraensis (Thermococcus kodakaraensis)
          Length = 195

 Score =  140 bits (352), Expect = 3e-32
 Identities = 89/203 (43%), Positives = 120/203 (59%), Gaps = 5/203 (2%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLN--RT 371
           + ++D G GN+ +VR A   LG  I     P  I  A+++V PGVG FG+ M+ L   R 
Sbjct: 2   IAVVDLGIGNLANVRKA---LGGVITS--DPYAIEGAEKIVLPGVGNFGAVMEKLEPLRG 56

Query: 372 GMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHI 551
            + DA+ +     +P LGICLGLQLLF+ SEE+    GLGV  G V RF   +G+ VPHI
Sbjct: 57  VIIDAIND----GKPLLGICLGLQLLFEGSEESPGKPGLGVFRGNVVRF---QGVRVPHI 109

Query: 552 GWNALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGES--FISSISMG 722
           GWN +   K+  L +G  DG + YFVHSY+ALP +     ++   + G    F S++   
Sbjct: 110 GWNQVWQRKECPLFEGIKDGAYFYFVHSYYALPEEDVTVGVTDYESKGAKVVFTSAVCRD 169

Query: 723 NIQAVQFHPEKSGATGLNIFENF 791
           N+ AVQFHPEKSG  GL + ENF
Sbjct: 170 NVYAVQFHPEKSGRNGLRLLENF 192

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>Q9A231:HIS5_CAUCR Imidazole glycerol phosphate synthase subunit hisH - Caulobacter|
           crescentus (Caulobacter vibrioides)
          Length = 213

 Score =  140 bits (352), Expect = 3e-32
 Identities = 80/209 (38%), Positives = 119/209 (56%), Gaps = 9/209 (4%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRH------LGFNIRDVRSPEDILAADRLVFPGVGAFGSAMD 356
           TV L+DYG+GN+RS   A+R       L  +I     P+ +  ADR+  PGVGAF S   
Sbjct: 3   TVALIDYGSGNLRSAEKALREAARRRALDADIVVTADPDLVAKADRVFLPGVGAFASCRA 62

Query: 357 VLNRTGMADALREYIR-MDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEG 533
            L+ TG+ +A+ + +     PF+GIC+G QLL     E G   GL  I G V++ + ++ 
Sbjct: 63  GLDATGVYEAMNQAVHGRGVPFMGICVGHQLLATEGLEFGVTPGLNWIQGQVKKLEPNDP 122

Query: 534 -LIVPHIGWNALQITKDTQLLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYGESFIS 707
            L +PH+GWNA+ + +   L  G D G H+YF +S+   PS      +  T ++G  F +
Sbjct: 123 TLTIPHMGWNAISLVRPHALFAGIDDGAHMYFANSFALTPSHVED--VVATADHGGPFTA 180

Query: 708 SISMGNIQAVQFHPEKSGATGLNIFENFL 794
           +++  N+  VQFHPEKS A+GL +  NFL
Sbjct: 181 AVAKDNVAGVQFHPEKSQASGLALLANFL 209

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>Q8YX49:HIS5_ANASP Imidazole glycerol phosphate synthase subunit hisH - Anabaena sp.|
           (strain PCC 7120)
          Length = 211

 Score =  140 bits (352), Expect = 3e-32
 Identities = 79/202 (39%), Positives = 116/202 (57%), Gaps = 2/202 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V ++DY  GN+ SV   +   G         +++  AD ++ PGVGAF  A+  L    +
Sbjct: 4   VAVIDYEMGNLHSVCKGLEKAGATPIITHCHQELTKADAVILPGVGAFDPAVQSLRSRDL 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
              +++ I   +PFLGICLGLQ+LF+SS E G   GLG+I G VRRF    G+ +PH+GW
Sbjct: 64  EQPIKDTIASGKPFLGICLGLQILFESSAE-GNQPGLGIIKGKVRRFVWEPGITIPHMGW 122

Query: 558 NALQITKDTQLL--QGADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQ 731
           N L++T+   +L         VYFVHSY+  P +      ++T +  ++  ++I+  N+ 
Sbjct: 123 NQLELTQPKSILWEHLPPQPWVYFVHSYYVDPFEPQVRAATVT-HGTQTVTAAIAHENLM 181

Query: 732 AVQFHPEKSGATGLNIFENFLS 797
           AVQFHPEKS   GL I  NF+S
Sbjct: 182 AVQFHPEKSSNIGLQILSNFVS 203

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>Q66C52:HIS5_YERPS Imidazole glycerol phosphate synthase subunit hisH - Yersinia|
           pseudotuberculosis
          Length = 196

 Score =  139 bits (351), Expect = 3e-32
 Identities = 82/200 (41%), Positives = 118/200 (59%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V +LD G  N+ SV  A++ LG+     R P  +L AD+L  PGVG   +AM+ L +  +
Sbjct: 3   VVILDTGCANLSSVTYAVQRLGYTPVISRDPAVVLRADKLFMPGVGTAHAAMEQLRQREL 62

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + ++      +P LGICLG+QLL  SSEE+G ++ LG+I   V++  +  GL +PH+GW
Sbjct: 63  IELIKS---CTQPVLGICLGMQLLATSSEESGGITTLGMIDAPVKKM-TDFGLPLPHMGW 118

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N +       L +G  DG + YFVH Y A+P   N   I+ T NYGE F +++   N   
Sbjct: 119 NQITAQAGNHLFRGIPDGTYFYFVHGY-AMPICPNT--IAQT-NYGEPFTAAVEKDNFFG 174

Query: 735 VQFHPEKSGATGLNIFENFL 794
           VQFHPE+SGA G  + +NFL
Sbjct: 175 VQFHPERSGAAGAQLMKNFL 194

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>Q8ZFX8:HIS5_YERPE Imidazole glycerol phosphate synthase subunit hisH - Yersinia|
           pestis
          Length = 196

 Score =  139 bits (351), Expect = 3e-32
 Identities = 82/200 (41%), Positives = 118/200 (59%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           V +LD G  N+ SV  A++ LG+     R P  +L AD+L  PGVG   +AM+ L +  +
Sbjct: 3   VVILDTGCANLSSVTYAVQRLGYTPVISRDPAVVLRADKLFMPGVGTAHAAMEQLRQREL 62

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + ++      +P LGICLG+QLL  SSEE+G ++ LG+I   V++  +  GL +PH+GW
Sbjct: 63  IELIKS---CTQPVLGICLGMQLLATSSEESGGITTLGMIDAPVKKM-TDFGLPLPHMGW 118

Query: 558 NALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N +       L +G  DG + YFVH Y A+P   N   I+ T NYGE F +++   N   
Sbjct: 119 NQITAQAGNHLFRGIPDGTYFYFVHGY-AMPICPNT--IAQT-NYGEPFTAAVEKDNFFG 174

Query: 735 VQFHPEKSGATGLNIFENFL 794
           VQFHPE+SGA G  + +NFL
Sbjct: 175 VQFHPERSGAAGAQLMKNFL 194

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>Q8P9P1:HIS5_XANCP Imidazole glycerol phosphate synthase subunit hisH - Xanthomonas|
           campestris pv. campestris
          Length = 200

 Score =  139 bits (351), Expect = 3e-32
 Identities = 82/200 (41%), Positives = 114/200 (57%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+D G  N+ SVR A+  LG   R VR  + +  A+R++ PGVGA   AM  L   G+
Sbjct: 4   LALIDAGGANLGSVRYALERLGVEARVVRDAQGLQGAERVILPGVGAAPEAMARLRAQGL 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + L++   +  P +GICLG+QLLF+ SEE G V  LG++PG+VR    + G+ VPH+GW
Sbjct: 64  IEPLQQ---LQVPLIGICLGMQLLFEHSEE-GDVDCLGMLPGIVRHMTPALGIRVPHMGW 119

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L   +D+ LL G  +    YFVH Y A P  A+       C++G  F + +  G    
Sbjct: 120 NQLVPMRDSALLAGLPERASAYFVHGY-AAPVTAD---TVAACDHGGLFTAVVQSGLRCG 175

Query: 735 VQFHPEKSGATGLNIFENFL 794
            QFHPE+S  TG  I  NFL
Sbjct: 176 AQFHPERSADTGARILRNFL 195

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>Q4UU43:HIS5_XANC8 Imidazole glycerol phosphate synthase subunit hisH - Xanthomonas|
           campestris pv. campestris (strain 8004)
          Length = 200

 Score =  139 bits (351), Expect = 3e-32
 Identities = 82/200 (41%), Positives = 114/200 (57%), Gaps = 1/200 (0%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + L+D G  N+ SVR A+  LG   R VR  + +  A+R++ PGVGA   AM  L   G+
Sbjct: 4   LALIDAGGANLGSVRYALERLGVEARVVRDAQGLQGAERVILPGVGAAPEAMARLRAQGL 63

Query: 378 ADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFDSSEGLIVPHIGW 557
            + L++   +  P +GICLG+QLLF+ SEE G V  LG++PG+VR    + G+ VPH+GW
Sbjct: 64  IEPLQQ---LQVPLIGICLGMQLLFEHSEE-GDVDCLGMLPGIVRHMTPALGIRVPHMGW 119

Query: 558 NALQITKDTQLLQG-ADGQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMGNIQA 734
           N L   +D+ LL G  +    YFVH Y A P  A+       C++G  F + +  G    
Sbjct: 120 NQLVPMRDSALLAGLPERASAYFVHGY-AAPVTAD---TVAACDHGGLFTAVVQSGLRCG 175

Query: 735 VQFHPEKSGATGLNIFENFL 794
            QFHPE+S  TG  I  NFL
Sbjct: 176 AQFHPERSADTGARILRNFL 195

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>Q63Q90:HIS5_BURPS Imidazole glycerol phosphate synthase subunit hisH - Burkholderia|
           pseudomallei (Pseudomonas pseudomallei)
          Length = 213

 Score =  139 bits (351), Expect = 3e-32
 Identities = 84/213 (39%), Positives = 120/213 (56%), Gaps = 10/213 (4%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHL--GFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNR 368
           ++ ++DYG GN+RSV  A+       +++ V  PE I AADR+V PG GA    M  L  
Sbjct: 4   SIAIVDYGMGNLRSVAQALMKAEPAADVKIVDRPEAIRAADRVVLPGQGAMPDCMRCLGE 63

Query: 369 TGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-------DSS 527
           +G+ +A+ E  R  +P LG+C+G Q+LFD S E G   GLG++PG V RF       D  
Sbjct: 64  SGLQEAVVEASRT-KPLLGVCVGEQMLFDWSAE-GDTKGLGLLPGKVVRFALEGRLQDDG 121

Query: 528 EGLIVPHIGWNALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFI 704
               VP +GWN ++ T+   L  G  D  + YFVHSY+ +P   N    +    YG+ F 
Sbjct: 122 SRFKVPQMGWNRVRQTQAHPLWDGVPDDAYFYFVHSYYVVPD--NPAHTAGETLYGDVFT 179

Query: 705 SSISMGNIQAVQFHPEKSGATGLNIFENFLSPN 803
           S+++  N+ A QFHPEKS   GL ++ NF+  N
Sbjct: 180 SAVARDNLFATQFHPEKSAEVGLRLYRNFVHWN 212

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>Q3JN00:HIS5_BURP1 Imidazole glycerol phosphate synthase subunit hisH - Burkholderia|
           pseudomallei (strain 1710b)
          Length = 213

 Score =  139 bits (351), Expect = 3e-32
 Identities = 84/213 (39%), Positives = 120/213 (56%), Gaps = 10/213 (4%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHL--GFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNR 368
           ++ ++DYG GN+RSV  A+       +++ V  PE I AADR+V PG GA    M  L  
Sbjct: 4   SIAIVDYGMGNLRSVAQALMKAEPAADVKIVDRPEAIRAADRVVLPGQGAMPDCMRCLGE 63

Query: 369 TGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-------DSS 527
           +G+ +A+ E  R  +P LG+C+G Q+LFD S E G   GLG++PG V RF       D  
Sbjct: 64  SGLQEAVVEASRT-KPLLGVCVGEQMLFDWSAE-GDTKGLGLLPGKVVRFALEGRLQDDG 121

Query: 528 EGLIVPHIGWNALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFI 704
               VP +GWN ++ T+   L  G  D  + YFVHSY+ +P   N    +    YG+ F 
Sbjct: 122 SRFKVPQMGWNRVRQTQAHPLWDGVPDDAYFYFVHSYYVVPD--NPAHTAGETLYGDVFT 179

Query: 705 SSISMGNIQAVQFHPEKSGATGLNIFENFLSPN 803
           S+++  N+ A QFHPEKS   GL ++ NF+  N
Sbjct: 180 SAVARDNLFATQFHPEKSAEVGLRLYRNFVHWN 212

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>Q62GE3:HIS5_BURMA Imidazole glycerol phosphate synthase subunit hisH - Burkholderia|
           mallei (Pseudomonas mallei)
          Length = 213

 Score =  139 bits (351), Expect = 3e-32
 Identities = 84/213 (39%), Positives = 120/213 (56%), Gaps = 10/213 (4%)
 Frame = +3

Query: 195 TVTLLDYGAGNVRSVRNAIRHL--GFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNR 368
           ++ ++DYG GN+RSV  A+       +++ V  PE I AADR+V PG GA    M  L  
Sbjct: 4   SIAIVDYGMGNLRSVAQALMKAEPAADVKIVDRPEAIRAADRVVLPGQGAMPDCMRCLGE 63

Query: 369 TGMADALREYIRMDRPFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRF-------DSS 527
           +G+ +A+ E  R  +P LG+C+G Q+LFD S E G   GLG++PG V RF       D  
Sbjct: 64  SGLQEAVVEASRT-KPLLGVCVGEQMLFDWSAE-GDTKGLGLLPGKVVRFALEGRLQDDG 121

Query: 528 EGLIVPHIGWNALQITKDTQLLQGA-DGQHVYFVHSYHALPSDANKDWISLTCNYGESFI 704
               VP +GWN ++ T+   L  G  D  + YFVHSY+ +P   N    +    YG+ F 
Sbjct: 122 SRFKVPQMGWNRVRQTQAHPLWDGVPDDAYFYFVHSYYVVPD--NPAHTAGETLYGDVFT 179

Query: 705 SSISMGNIQAVQFHPEKSGATGLNIFENFLSPN 803
           S+++  N+ A QFHPEKS   GL ++ NF+  N
Sbjct: 180 SAVARDNLFATQFHPEKSAEVGLRLYRNFVHWN 212

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>Q9S4H8:HIS52_LEPIN Imidazole glycerol phosphate synthase subunit hisH - Leptospira|
           interrogans
          Length = 204

 Score =  139 bits (351), Expect = 3e-32
 Identities = 76/205 (37%), Positives = 125/205 (60%), Gaps = 5/205 (2%)
 Frame = +3

Query: 198 VTLLDYGAGNVRSVRNAIRHLGFNIRDVRSPEDILAADRLVFPGVGAFGSAMDVLNRTGM 377
           + +LDYG GN+++  N ++ L F  + V++ +++ +  +++ PGVG+F S MD L+ +G+
Sbjct: 2   IGILDYGVGNLKAFANVLKDLNFRNQIVKTEQELKSCTKIIMPGVGSFDSVMDKLSESGI 61

Query: 378 ADALREYIRMDR-PFLGICLGLQLLFDSSEENGPVSGLGVIPGVVRRFD---SSEGLIVP 545
            D L + +   + P LG+C+G+Q+L  SSEE G  SGLG I G V++F+   S+  L VP
Sbjct: 62  RDVLSDLVMSKKIPVLGVCVGMQILASSSEE-GTKSGLGWIQGKVKKFNFDQSNSLLTVP 120

Query: 546 HIGWNALQITKDTQLLQGAD-GQHVYFVHSYHALPSDANKDWISLTCNYGESFISSISMG 722
            IGWN +   +D +LL   +     YF+HSY+ +  + + D I+   +YG +F  +++  
Sbjct: 121 QIGWNEVTSIRDNKLLLNLEKNPRFYFLHSYY-MECEEDNDVIAF-ADYGGNFTCAVNRD 178

Query: 723 NIQAVQFHPEKSGATGLNIFENFLS 797
           NI   QFHPEKS   G+ +  NF S
Sbjct: 179 NIFGTQFHPEKSHHNGVALLRNFAS 203

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>Q8FY07:HIS6_BRUSU Imidazole glycerol phosphate synthase subunit hisF - Brucella suis|
          Length = 261

 Score =  139 bits (350), Expect = 4e-32
 Identities = 106/313 (33%), Positives = 149/313 (47%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L  RVI CLDV+     D  V KG  +         ++ + G PVE A  Y   GADE+ 
Sbjct: 3    LKARVIPCLDVK-----DGRVVKGVNF--------VDLIDAGDPVEAARAYDAAGADELC 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       + +V+   +E+ F+PLTVGGG+R   D             +   
Sbjct: 50   FLDIT---ASSDNRETIFDVVARTAEQCFMPLTVGGGVRQVAD-----------IRKLLL 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV   E   +   K            +GNQ +VV+ID ++V        
Sbjct: 96   AGADKVSINTAAVKNPEFVAEAADK------------FGNQCIVVAIDAKKV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W +    GGR    I A E A+ V +LGAGEILL  +D DG 
Sbjct: 136  ----------SGAGENDRW-EIFTHGGRQPTGIDAVEFAQKVVDLGAGEILLTSMDRDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L + V+D+V  PVIAS G G ++H        +A+A LAA IFH     I   
Sbjct: 185  KAGYDVALTRAVADSVRAPVIASGGVGTLDHLVAGIRDGHATAVLAASIFHFGTYTIGEA 244

Query: 1746 KEHLVDAGVEVRM 1784
            K ++ +AG+ +R+
Sbjct: 245  KRYMAEAGIPMRL 257

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>Q57AH3:HIS6_BRUAB Imidazole glycerol phosphate synthase subunit hisF - Brucella abortus|
          Length = 261

 Score =  139 bits (350), Expect = 4e-32
 Identities = 106/313 (33%), Positives = 149/313 (47%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L  RVI CLDV+     D  V KG  +         ++ + G PVE A  Y   GADE+ 
Sbjct: 3    LKARVIPCLDVK-----DGRVVKGVNF--------VDLIDAGDPVEAARAYDAAGADELC 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       + +V+   +E+ F+PLTVGGG+R   D             +   
Sbjct: 50   FLDIT---ASSDNRETIFDVVARTAEQCFMPLTVGGGVRQVAD-----------IRKLLL 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV   E   +   K            +GNQ +VV+ID ++V        
Sbjct: 96   AGADKVSINTAAVKNPEFVAEAADK------------FGNQCIVVAIDAKKV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W +    GGR    I A E A+ V +LGAGEILL  +D DG 
Sbjct: 136  ----------SGAGENDRW-EIFTHGGRQPTGIDAVEFAQKVVDLGAGEILLTSMDRDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L + V+D+V  PVIAS G G ++H        +A+A LAA IFH     I   
Sbjct: 185  KAGYDVALTRAVADSVRAPVIASGGVGTLDHLVAGIRDGHATAVLAASIFHFGTYTIGEA 244

Query: 1746 KEHLVDAGVEVRM 1784
            K ++ +AG+ +R+
Sbjct: 245  KRYMAEAGIPMRL 257

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>Q2YQY8:HIS6_BRUA2 Imidazole glycerol phosphate synthase subunit hisF - Brucella abortus|
            (strain 2308)
          Length = 261

 Score =  139 bits (350), Expect = 4e-32
 Identities = 106/313 (33%), Positives = 149/313 (47%)
 Frame = +3

Query: 846  LAKRVIACLDVRSNDNGDLVVTKGDQYDVRDHSSSKEVRNLGKPVELASQYYIDGADEVS 1025
            L  RVI CLDV+     D  V KG  +         ++ + G PVE A  Y   GADE+ 
Sbjct: 3    LKARVIPCLDVK-----DGRVVKGVNF--------VDLIDAGDPVEAARAYDAAGADELC 49

Query: 1026 FLNITGFRAFPLGDLPMLEVLRCASEKVFVPLTVGGGIRDFTDESGRYYSSLEVASEYFR 1205
            FL+IT   A       + +V+   +E+ F+PLTVGGG+R   D             +   
Sbjct: 50   FLDIT---ASSDNRETIFDVVARTAEQCFMPLTVGGGVRQVAD-----------IRKLLL 95

Query: 1206 SGADKISIGSDAVFAAEAYLQTGVKTGKSSLEQISRVYGNQAVVVSIDPRRVYVKSPDEV 1385
            +GADK+SI + AV   E   +   K            +GNQ +VV+ID ++V        
Sbjct: 96   AGADKVSINTAAVKNPEFVAEAADK------------FGNQCIVVAIDAKKV-------- 135

Query: 1386 QFRTVKVSSKGPLGEEYAWYQCTVSGGRDSRPIGAYELAKAVEELGAGEILLNCIDCDGQ 1565
                         GE   W +    GGR    I A E A+ V +LGAGEILL  +D DG 
Sbjct: 136  ----------SGAGENDRW-EIFTHGGRQPTGIDAVEFAQKVVDLGAGEILLTSMDRDGT 184

Query: 1566 GGGFDIDLIKMVSDAVTIPVIASSGAGAVEHFSEVFEKTNASAALAAGIFHRKEVPILAV 1745
              G+D+ L + V+D+V  PVIAS G G ++H        +A+A LAA IFH     I   
Sbjct: 185  KAGYDVALTRAVADSVRAPVIASGGVGTLDHLVAGIRDGHATAVLAASIFHFGTYTIGEA 244

Query: 1746 KEHLVDAGVEVRM 1784
            K ++ +AG+ +R+
Sbjct: 245  KRYMAEAGIPMRL 257


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 333,156,825
Number of extensions: 7374713
Number of successful extensions: 25473
Number of sequences better than 10.0: 856
Number of HSP's gapped: 23795
Number of HSP's successfully gapped: 920
Length of query: 661
Length of database: 100,686,439
Length adjustment: 120
Effective length of query: 541
Effective length of database: 67,771,039
Effective search space: 36664132099
Effective search space used: 36664132099
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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full-length cDNA and EST

Clone Information

BLAST Search Result