ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf129f05 |
|---|---|
| Clone Library Name | barley_pub |
>Q9SJ20:RIR1_ARATH Ribonucleoside-diphosphate reductase large subunit - Arabidopsis| thaliana (Mouse-ear cress) Length = 816 Score = 1334 bits (3452), Expect = 0.0 Identities = 651/820 (79%), Positives = 710/820 (86%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 MYVVKRDGR ETVHFDKITARLKKLSYGLS +HCDPVLVAQKVCAGVYKGVTTSQLD Sbjct: 1 MYVVKRDGRQETVHFDKITARLKKLSYGLSSDHCDPVLVAQKVCAGVYKGVTTSQLDELA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 +HPDYASLAARIAVSNLHKNTKKSFSETIKDM+ H N+RSGL SPLIA+D+ Sbjct: 61 AETAAAMTCNHPDYASLAARIAVSNLHKNTKKSFSETIKDMFYHVNDRSGLKSPLIADDV 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 +E+IM+NAARLDSEII KTLERSYLLK+ G VVERPQHMLMRV+VGIHK Sbjct: 121 FEIIMQNAARLDSEIIYDRDFEYDYFGFKTLERSYLLKVQGTVVERPQHMLMRVAVGIHK 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DDIDS I+TYHLMSQRWFTHASPTLFNAGTPRPQLSSCFL+CMKDDSIEGIY+TLKECAV Sbjct: 181 DDIDSVIQTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLVCMKDDSIEGIYETLKECAV 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY Sbjct: 241 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWHAD++EFL+LRKNHGKEE+RARDLF+ALW+PDLFM+RVQNN WS FCPNEAPGLA Sbjct: 301 LEPWHADVYEFLELRKNHGKEEHRARDLFYALWLPDLFMERVQNNGQWSLFCPNEAPGLA 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 DCWG V+ AQ LW++IL +Q+ETGTPYML+KDSCNRKSNQQNL Sbjct: 361 DCWGAEFETLYTKYEREGKAKKVVQAQQLWYEILTSQVETGTPYMLFKDSCNRKSNQQNL 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIKSSNLCTEIIE+TSP ETAVCNLASIALPRFVREKGVP++SHP KLAGS SKNRYF Sbjct: 421 GTIKSSNLCTEIIEYTSPTETAVCNLASIALPRFVREKGVPLDSHPPKLAGSLDSKNRYF 480 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF+KL EVT+TVT NLNKII++NYYPVETA+ SNMRHRPIGIGVQGLAD F+LLGMPFDS Sbjct: 481 DFEKLAEVTATVTVNLNKIIDVNYYPVETAKTSNMRHRPIGIGVQGLADAFILLGMPFDS 540 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 PEAQQLN+DIFETIYYH GPYETY GSPVSKGI+QPDMWNV+PS RW+W Sbjct: 541 PEAQQLNKDIFETIYYHALKASTELAARLGPYETYAGSPVSKGILQPDMWNVIPSDRWDW 600 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 LR+ I+K GVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL Sbjct: 601 AVLRDMISKNGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 660 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 LHDLT+MG+WTP LKNK+I E+GSI + EIPDDLKAIY+TVWEIKQ+T+VDMA DRGCY Sbjct: 661 LHDLTDMGLWTPTLKNKLINENGSIVNVAEIPDDLKAIYRTVWEIKQRTVVDMAADRGCY 720 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLKVXX 2429 IDQSQSLN+HMD+PNFAKLTSLHF+ W KGLKTGMYYLR+RAAADAIKFTVDT LK Sbjct: 721 IDQSQSLNIHMDKPNFAKLTSLHFYTWKKGLKTGMYYLRSRAAADAIKFTVDTAMLK--- 777 Query: 2430 XXXXXXXXXXXKLAEEDDEAKMAQVVCSLNNREECLACGS 2549 ++ EED+E K+AQ+VCSL N EECLACGS Sbjct: 778 -EKPSVAEGDKEVEEEDNETKLAQMVCSLTNPEECLACGS 816
>P07742:RIR1_MOUSE Ribonucleoside-diphosphate reductase large subunit - Mus musculus| (Mouse) Length = 792 Score = 1023 bits (2646), Expect = 0.0 Identities = 507/820 (61%), Positives = 603/820 (73%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 M+V+KRDGR E V FDKIT+R++KL YGL+ + DP + KV G+Y GVTT +LD Sbjct: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA LAARIAVSNLHK TKK FS+ ++D+Y + N +G SP++A Sbjct: 61 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASST 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 +++M N RL+S II KTLERSYLLK+ G V ERPQHMLMRVSVGIHK Sbjct: 121 LDIVMANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 +DID+AI TY+L+S++WFTHA PTLFNAGT RPQLSSCFL+ MKDDSIEGIYDTLK+CA+ Sbjct: 181 EDIDAAIETYNLLSEKWFTHAPPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISKSAGGIGV+V IRATGSYI GTNG SNG+VPMLRV+N+TARYVDQGG KR GAFA+Y Sbjct: 241 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWH DIFEFLDL+KN GKEE RARDLFFALW+PDLFM+RV+ N+DWS CPNE PGL Sbjct: 301 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 + WG V+ AQ LW+ I+++Q ETGTPYMLYKDSCNRKSNQQNL Sbjct: 361 EVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIK SNLCTEI+E+TS +E AVCNLAS+AL +V + + Sbjct: 421 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYV-------------------TPEHTY 461 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF+KL EVT + NLNKII++NYYP+ A SN RHRPIGIGVQGLAD F+L+ PF+S Sbjct: 462 DFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFES 521 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 PEAQ LN+ IFETIYY GPYETYEGSPVSKGI+Q DMWNV P+ W+W Sbjct: 522 PEAQLLNKQIFETIYYGALEASCELAKEYGPYETYEGSPVSKGILQYDMWNVAPTDLWDW 581 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L+E IAK G+RNSLL+APMPTAST+QILGNNE EPYTSNIY+RRVLSGEF +VN HL Sbjct: 582 KPLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHL 641 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L DLTE G+W +KN+II +GSIQ + EIPDDLK +YKTVWEI QKT++ MA +RG + Sbjct: 642 LKDLTERGLWNKEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAF 701 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLKVXX 2429 IDQSQSLN+H+ +PN+ KLTS+HF+ W +GLKTGMYYLRTR AA+ I+FT++ LK Sbjct: 702 IDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLK--- 758 Query: 2430 XXXXXXXXXXXKLAEEDDEAKMAQVVCSLNNREECLACGS 2549 EE+ E A +VCSL NREECL CGS Sbjct: 759 ------DKEKALKEEEEKERNTAAMVCSLENREECLMCGS 792
>P23921:RIR1_HUMAN Ribonucleoside-diphosphate reductase large subunit - Homo sapiens| (Human) Length = 792 Score = 1021 bits (2639), Expect = 0.0 Identities = 508/820 (61%), Positives = 603/820 (73%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 M+V+KRDGR E V FDKIT+R++KL YGL+ + DP + KV G+Y GVTT +LD Sbjct: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA LAARIAVSNLHK TKK FS+ ++D+Y + N +G SP++A+ Sbjct: 61 AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKST 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 ++++ N RL+S II KTLERSYLLK+ G V ERPQHMLMRVSVGIHK Sbjct: 121 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 +DID+AI TY+L+S+RWFTHASPTLFNAGT RPQLSSCFL+ MKDDSIEGIYDTLK+CA+ Sbjct: 181 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISKSAGGIGV+V IRATGSYI GTNG SNG+VPMLRV+N+TARYVDQGG KR GAFA+Y Sbjct: 241 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWH DIFEFLDL+KN GKEE RARDLFFALW+PDLFM+RV+ N+DWS CPNE PGL Sbjct: 301 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 + WG V+ AQ LW+ I+++Q ETGTPYMLYKDSCNRKSNQQNL Sbjct: 361 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIK SNLCTEI+E+TS +E AVCNLAS+AL +V + + Sbjct: 421 GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYV-------------------TSEHTY 461 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF KL EVT V NLNKII++NYYPV A SN RHRPIGIGVQGLAD F+L+ PF+S Sbjct: 462 DFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFES 521 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 EAQ LN+ IFETIYY GPYETYEGSPVSKGI+Q DMWNV P+ W+W Sbjct: 522 AEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDW 581 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L+E IAK G+RNSLL+APMPTAST+QILGNNE EPYTSNIY+RRVLSGEF +VN HL Sbjct: 582 KVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHL 641 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L DLTE G+W +KN+II +GSIQ + EIPDDLK +YKTVWEI QKT++ MA +RG + Sbjct: 642 LKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAF 701 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLKVXX 2429 IDQSQSLN+H+ +PN+ KLTS+HF+ W +GLKTGMYYLRTR AA+ I+FT++ LK Sbjct: 702 IDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLK--- 758 Query: 2430 XXXXXXXXXXXKLAEEDDEAKMAQVVCSLNNREECLACGS 2549 EE+ E A +VCSL NR+ECL CGS Sbjct: 759 ------DKEKVSKEEEEKERNTAAMVCSLENRDECLMCGS 792
>Q5R919:RIR1_PONPY Ribonucleoside-diphosphate reductase large subunit - Pongo pygmaeus| (Orangutan) Length = 792 Score = 1016 bits (2628), Expect = 0.0 Identities = 506/820 (61%), Positives = 602/820 (73%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 M+V+KRDGR E V FDKIT+R++KL YGL+ + DP + KV G+Y GVTT +LD Sbjct: 1 MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA LAARIAVSNLHK KK FS+ ++D+Y + N +G SP++A+ Sbjct: 61 AETAATLTTKHPDYAILAARIAVSNLHKEAKKVFSDVMEDLYNYINPHNGKHSPMVAKST 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 ++++ N RL+S II KTLERSYLLK+ G V ERPQHMLMRVSVGIHK Sbjct: 121 LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 +DID+AI TY+L+S+RWFTHASPTLFNAGT RPQLSSCFL+ MKDDSIEGIYDTLK+CA+ Sbjct: 181 EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISKSAGGIGV+V IRATGSYI GTNG SNG+VPMLRV+N+TARYVDQGG KR GAFA+Y Sbjct: 241 ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWH DIFEFLDL+KN GKEE RARDLFFALW+PDLFM+RV+ N+DWS CPNE PGL Sbjct: 301 LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 + WG V+ AQ LW+ I+++Q ETGTPYMLYKDSCNRKSNQQNL Sbjct: 361 EVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIK S+LCTEI+E+TS +E AVCNLAS+AL +V + + Sbjct: 421 GTIKCSSLCTEIVEYTSKDEVAVCNLASLALNMYV-------------------TSEHTY 461 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF KL EVT V NLNKII++NYYPV A SN RHRPIGIGVQGLAD F+L+ PF+S Sbjct: 462 DFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFES 521 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 EAQ LN+ IFETIYY GPYETYEGSPVSKGI+Q DMWNV P+ W+W Sbjct: 522 AEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDLWDW 581 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L+E IAK G+RNSLL+APMPTAST+QILGNNE EPYTSNIY+RRVLSGEF +VN HL Sbjct: 582 KLLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHL 641 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L DLTE G+W +KN+II +GSIQ + EIPDDLK +YKTVWEI QKT++ MA +RG + Sbjct: 642 LKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAF 701 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLKVXX 2429 IDQSQSLN+H+ +PN+ KLTS+HF+ W +GLKTGMYYLRTR AA+ I+FT++ LK Sbjct: 702 IDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLK--- 758 Query: 2430 XXXXXXXXXXXKLAEEDDEAKMAQVVCSLNNREECLACGS 2549 EE+ E A +VCSL NR+ECL CGS Sbjct: 759 ------DKEKVSKEEEEKERNTAAMVCSLENRDECLMCGS 792
>P79732:RIR1_DANRE Ribonucleoside-diphosphate reductase large subunit - Danio rerio| (Zebrafish) (Brachydanio rerio) Length = 794 Score = 990 bits (2559), Expect = 0.0 Identities = 494/820 (60%), Positives = 590/820 (71%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 M+V+KRDG E V FDKIT+R++KL YGL+ + DP + KV G+Y GVTT +LD Sbjct: 1 MHVIKRDGGQEGVMFDKITSRIQKLCYGLNSDFVDPTQITMKVIQGLYSGVTTVELDTLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA LAARIAVSNLHK TKK FSE ++D+Y + N + SP+I+++ Sbjct: 61 AETAATSTTKHPDYAILAARIAVSNLHKETKKVFSEVMEDLYNYVNPLNSRHSPMISKET 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 ++++ N RL+S II KTLERSYLLK+ G V ERPQHMLMRVSVGIHK Sbjct: 121 LDIVLANKDRLNSAIIYDRDFSYNFFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 +DI +AI TY+L+S++WFTHASPTLFNAGT RPQLSSCFL+ MKDDSIEGIYDTLK+CA+ Sbjct: 181 EDIAAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLAMKDDSIEGIYDTLKQCAL 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISKSAGGIGV+V IRATG YI GTNG SNG+VPMLRV N+TARYVDQGG KR GAFA+Y Sbjct: 241 ISKSAGGIGVAVSCIRATGRYIAGTNGNSNGLVPMLRVNNNTARYVDQGGNKRPGAFAMY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWH DIF+FL+L+KN GKEE RARDLF+ALW+PDLFM+RV+ N DWS CPN+ PGL Sbjct: 301 LEPWHFDIFDFLELKKNTGKEEQRARDLFYALWIPDLFMKRVETNGDWSLMCPNDCPGLD 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 +CWG V+ AQ LW+ I+++Q ETGTPYMLYKD+CNRKSN+QNL Sbjct: 361 ECWGEEFEKLYAKYEQEGRAKRVVKAQQLWYAIIESQTETGTPYMLYKDACNRKSNRQNL 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIK SNLCTEI+E+TS +E AVCNLASIAL +V + R F Sbjct: 421 GTIKCSNLCTEIVEYTSADEVAVCNLASIALNMYV-------------------TSERTF 461 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF KL VT + NLNKII++NYYPV+ A SN RHRPIGIGVQGLAD F+L+ PF+S Sbjct: 462 DFQKLASVTKVIVKNLNKIIDINYYPVKEAENSNKRHRPIGIGVQGLADAFILMRFPFES 521 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 EAQ LN IFETIYY GPY+TY G PVSKGI+Q DMW P+ W+W Sbjct: 522 TEAQLLNTQIFETIYYAALESSCELAAEYGPYQTYAGCPVSKGILQYDMWEKTPTDLWDW 581 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L+E IA GVRNSLL+APMPTAST+QILGNNE EPYTSNIY RRVLSGEF +VN HL Sbjct: 582 AALKEKIANDGVRNSLLLAPMPTASTAQILGNNESIEPYTSNIYHRRVLSGEFQIVNPHL 641 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L DLTE G+W +KN+II ++GSIQ + IPDDLK +YKTVWEI QKT++ MA DRG Y Sbjct: 642 LKDLTERGLWNEEMKNQIIAQNGSIQTIPAIPDDLKELYKTVWEISQKTILKMAADRGAY 701 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLKVXX 2429 IDQSQSLN+H+ +PN+ KLTS+HF+ W +GLKTGMYYLRT+ A+ I+FT++ LK Sbjct: 702 IDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTKPGANPIQFTLNKEKLKETQ 761 Query: 2430 XXXXXXXXXXXKLAEEDDEAKMAQVVCSLNNREECLACGS 2549 EE E A +VCSL NR ECL CGS Sbjct: 762 KTTSSED-------EETKERNKAAMVCSLENRHECLMCGS 794
>Q9UW15:RIR1_NEUCR Ribonucleoside-diphosphate reductase large chain - Neurospora crassa| Length = 929 Score = 989 bits (2556), Expect = 0.0 Identities = 488/777 (62%), Positives = 578/777 (74%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 MYV KRDGR E V FDKITAR+ +L YGL H DPV + QKV +GVY GVTT+QLD Sbjct: 1 MYVKKRDGRQERVQFDKITARVSRLCYGLDMNHVDPVAITQKVISGVYGGVTTAQLDDLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 +HPDYA LAARIAVSNLHK TKK +S I ++Y + N R+G SP+IA+D+ Sbjct: 61 AETAAYMTVTHPDYAILAARIAVSNLHKQTKKQWSLVISELYNYVNPRTGKHSPMIAKDV 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 YE +M++ DS I+ KTLERSYLLKL G + ERPQHM+MRV+VGI Sbjct: 121 YECVMRHKDEFDSAIVYDRDFNYQYFGFKTLERSYLLKLDGQIAERPQHMIMRVAVGIWG 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DD++ I TY+LMS + FTHASPTLFNAGTP+PQLSSCFL+ MK+DSIEGIYDTLK CA+ Sbjct: 181 DDVERVIETYNLMSLKTFTHASPTLFNAGTPQPQLSSCFLVDMKEDSIEGIYDTLKTCAM 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK AGGIG+++H IRATGSYI GTNGTSNGIVPMLRVFN+TARYVDQGG KR GAFA+Y Sbjct: 241 ISKMAGGIGLNIHRIRATGSYIAGTNGTSNGIVPMLRVFNNTARYVDQGGNKRPGAFAIY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWHAD+FEFLDLRKNHGKEE RARDLF ALW+PDLFM+RV+ N W+ CP+E PGLA Sbjct: 301 LEPWHADVFEFLDLRKNHGKEEVRARDLFLALWIPDLFMKRVEQNGQWTLMCPHECPGLA 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 D +G + AQ LW+ IL+AQ ETG P+MLYKD+CNRKSNQ+NL Sbjct: 361 DVYGDEFEALYEKYEKEGKGRKTVKAQKLWYAILEAQTETGNPFMLYKDACNRKSNQKNL 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTI+SSNLCTEIIE+++P+E AVCNLAS+AL F+ +N + Sbjct: 421 GTIRSSNLCTEIIEYSAPDEVAVCNLASLALSAFI------------------DYENASY 462 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF KL EVT V NLNKII++N+YPV+ A SNMRHRPIG+GVQGLAD F+ L MPFDS Sbjct: 463 DFKKLHEVTQVVVRNLNKIIDINHYPVKEAHNSNMRHRPIGVGVQGLADAFLALRMPFDS 522 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 A +LN IFETIY+ GPY TYEGSPVS+GI+Q DMWNV P+ W+W Sbjct: 523 DAASKLNIQIFETIYHAALTASCQLAKEQGPYATYEGSPVSQGILQYDMWNVTPTNLWDW 582 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L+ I K GVRNSLL+APMPTASTSQILGNNECFEPYTSNIY RRVL+GEF VVN L Sbjct: 583 TALKADIKKYGVRNSLLLAPMPTASTSQILGNNECFEPYTSNIYQRRVLAGEFQVVNPWL 642 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L DL EMG+W+ A+KN+II E GSIQ ++ IP+D+KA+YKTVWEI Q+T+V MA DRG + Sbjct: 643 LRDLVEMGLWSDAMKNRIIAEGGSIQNIQSIPNDIKALYKTVWEISQRTIVKMAADRGAF 702 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLK 2420 IDQSQSLN+HM +P K+TS+HF W GLKTGMYYLRT+AAA I+FTVD L+ Sbjct: 703 IDQSQSLNIHMREPTMGKITSMHFAGWKMGLKTGMYYLRTQAAAQPIQFTVDQEALR 759
>P36602:RIR1_SCHPO Ribonucleoside-diphosphate reductase large chain -| Schizosaccharomyces pombe (Fission yeast) Length = 811 Score = 984 bits (2543), Expect = 0.0 Identities = 487/831 (58%), Positives = 596/831 (71%), Gaps = 11/831 (1%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 M+V KRDGR E V FDKITAR+ +L YGL +H DPV + QKV +GVY GVTT +LD Sbjct: 1 MFVYKRDGRQEKVAFDKITARVSRLCYGLDSDHVDPVEITQKVISGVYPGVTTIELDNLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA LAARIAVSNLHK T+K FS ++ ++ + N ++ +P+I++ I Sbjct: 61 AETAATMTTKHPDYAILAARIAVSNLHKQTEKVFSTVVQQLHDYVNPKTDKPAPMISDKI 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 Y+++MK+ LDS II KTLERSYLL++ G V ERPQHM+MRV+VGIH Sbjct: 121 YDIVMKHKDELDSAIIYDRDFTYNFFGFKTLERSYLLRIDGKVAERPQHMIMRVAVGIHG 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 +DI++AI TY+LMSQR+FTHASPTLFNAGTPRPQLSSCFL+ MKDDSIEGIYDTLK CA+ Sbjct: 181 EDIEAAIETYNLMSQRYFTHASPTLFNAGTPRPQLSSCFLVTMKDDSIEGIYDTLKMCAM 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK+AGGIG+++HNIRATGSYI GTNGTSNGIVPM+RV+N+TARYVDQGG KR GAFA Y Sbjct: 241 ISKTAGGIGINIHNIRATGSYIAGTNGTSNGIVPMIRVYNNTARYVDQGGNKRPGAFAAY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWHAD+ +FL+LRK HG E+ RAR++F+ALW+PDLFMQRV+ NE W+ FCPNEAPGLA Sbjct: 301 LEPWHADVMDFLELRKTHGNEDFRAREMFYALWIPDLFMQRVERNEQWTFFCPNEAPGLA 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 D WG +PAQ +W+ IL++Q+ETG P+MLYKDSCNRKSNQ+N+ Sbjct: 361 DVWGDEFVALYEKYEKENRGRRSLPAQKVWYAILQSQVETGNPFMLYKDSCNRKSNQKNV 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTI+ SNLCTEI+E++SP+E AVCNLAS+ALP F+ K+ + Sbjct: 421 GTIRCSNLCTEIVEYSSPDEVAVCNLASVALPTFI--------------------KDGKY 460 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 +F KL +V VT NLNKII++NYYPV ARRSNMRHRP+G+GVQGLAD F L +PF+S Sbjct: 461 NFQKLHDVVKVVTRNLNKIIDVNYYPVPEARRSNMRHRPVGLGVQGLADAFFALRLPFES 520 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 A++LN IFETIY+ G YE+YEGSP S+GI+Q DMWNV P+ W+W Sbjct: 521 AGAKKLNIQIFETIYHAALEASCEIAQVEGTYESYEGSPASQGILQYDMWNVNPTDLWDW 580 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L+E IAK G+RNSLLVAPMPTASTSQILG NECFEPYTSN+Y RRVLSGEF +VN L Sbjct: 581 AELKEKIAKHGIRNSLLVAPMPTASTSQILGFNECFEPYTSNMYQRRVLSGEFQIVNPWL 640 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L DL E +W +KNK++ DGSIQ + EIP DLK +YKTVWEI QKT++D A DRG + Sbjct: 641 LKDLVERDLWNEDMKNKLVMLDGSIQAIPEIPQDLKDLYKTVWEISQKTVIDYAADRGPF 700 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFL---- 2417 IDQSQSLN+H+ P++ K+TS+HF+ W KGLKTGMYYLRT AA+ AIKFTVD L Sbjct: 701 IDQSQSLNIHLKDPSYGKITSMHFYGWKKGLKTGMYYLRTMAASAAIKFTVDPVALRARN 760 Query: 2418 -------KVXXXXXXXXXXXXXKLAEEDDEAKMAQVVCSLNNREECLACGS 2549 K EE D + CS+ N E C C + Sbjct: 761 EESNEENKKPVIKNGKAEISAEPTKEEIDIYNEKVLACSIKNPEACEMCSA 811
>P48591:RIR1_DROME Ribonucleoside-diphosphate reductase large subunit - Drosophila| melanogaster (Fruit fly) Length = 812 Score = 977 bits (2526), Expect = 0.0 Identities = 479/821 (58%), Positives = 600/821 (73%) Frame = +3 Query: 87 KMYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXX 266 K+YV+KRDGR E VHFDKIT+R++KL Y L+ + DPV + +V G+Y GVTT +LD Sbjct: 11 KLYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVINGLYCGVTTQELDNL 70 Query: 267 XXXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAED 446 +HPDYA LAARIAVSNLHK TKK+FS+ +D+Y H N+ + PL++E Sbjct: 71 AAEIAAGLTCNHPDYAILAARIAVSNLHKETKKAFSDVFEDLYNHVNKETNQKVPLVSEF 130 Query: 447 IYEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIH 626 Y V+ KNA RL+S II KTLERSYLLK G + ERPQHMLMRV++GIH Sbjct: 131 HYNVVKKNATRLNSSIIYDRDFGYNYFGFKTLERSYLLKRNGKIAERPQHMLMRVAIGIH 190 Query: 627 KDDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECA 806 +DID+A+ TY+L+S+R+FTHASPTLF A T RPQLSSCFL+ M DSIEGI+ ++++CA Sbjct: 191 GEDIDAAVETYNLLSERYFTHASPTLFAAATNRPQLSSCFLLTMTADSIEGIFKSVEQCA 250 Query: 807 VISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAV 986 +ISKSAGGIG++VH IRA G+ I GTNGTSNG+VPMLRVFN+ ARYVDQGGGKR GAFA+ Sbjct: 251 MISKSAGGIGLNVHCIRAKGTSICGTNGTSNGLVPMLRVFNNVARYVDQGGGKRPGAFAI 310 Query: 987 YLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGL 1166 YLEPWH+D+FEFL+L+KN GKEENRARDLF+ALW+PDLFM+RV+ N DWS CP++ PGL Sbjct: 311 YLEPWHSDVFEFLELKKNTGKEENRARDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGL 370 Query: 1167 ADCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQN 1346 D WG + AQ+LWF I++AQ+ETG PYML+KD+CNRKSNQQN Sbjct: 371 HDVWGDEFEKLYEKYEQEGRANRTVKAQSLWFAIIEAQVETGNPYMLFKDACNRKSNQQN 430 Query: 1347 LGTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRY 1526 +GTIK SNLCTEI+E+++P+E AVCNLASIAL FV + + Sbjct: 431 VGTIKCSNLCTEIVEYSAPDEIAVCNLASIALNMFV-------------------TPEKT 471 Query: 1527 FDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFD 1706 +DF KL EVT VT NLNKII++NYYP+ AR+SN+RHRP+GIG+QG AD +L+ P++ Sbjct: 472 YDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYE 531 Query: 1707 SPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWN 1886 S EA LN+ IFETIYY GPYETYEGSPVSKGI+Q DMW+ VP+ W+ Sbjct: 532 SEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNLWD 591 Query: 1887 WPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKH 2066 W L+E+I GVRNSLLVAPMPTAST+QI+GNNE FEPYT+NIY+RRVLSGEF VVN H Sbjct: 592 WQKLKESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFQVVNHH 651 Query: 2067 LLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGC 2246 LL DLTE+ +W +KN+II GSIQ +E IP ++ +YKTVWEI K+ + MA DRG Sbjct: 652 LLRDLTELDLWDDDMKNQIISSRGSIQNIETIPPKVRDLYKTVWEISVKSTIKMAADRGA 711 Query: 2247 YIDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLKVX 2426 +IDQSQS N+H+ +PN+ KLTS+HF++W GLKTGMYYLRT+ AA+AI+FTV+ V Sbjct: 712 FIDQSQSFNIHVAEPNYGKLTSIHFYSWKAGLKTGMYYLRTKPAANAIQFTVNKKQGAVS 771 Query: 2427 XXXXXXXXXXXXKLAEEDDEAKMAQVVCSLNNREECLACGS 2549 + EED E KMA +VCSL N++ C++CGS Sbjct: 772 MNGQNGTAEGSPQKYEEDRERKMADMVCSLENKDACMSCGS 812
>Q03604:RIR1_CAEEL Ribonucleoside-diphosphate reductase large subunit - Caenorhabditis| elegans Length = 788 Score = 962 bits (2487), Expect = 0.0 Identities = 474/776 (61%), Positives = 579/776 (74%) Frame = +3 Query: 93 YVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXXX 272 YVVKRDGR E VHFDKIT+R++KLSYGL+ + DPV VA KV +G+YKGVTT +LD Sbjct: 8 YVVKRDGRKEDVHFDKITSRIQKLSYGLNMDFVDPVAVAIKVISGLYKGVTTVELDNLAA 67 Query: 273 XXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDIY 452 HP+YA LAARIAVSNLHK T K FSE +K ++ ++ +G +P+I+++ + Sbjct: 68 ETAASMTTQHPEYALLAARIAVSNLHKKTNKVFSEVMKTLHEFHHPHTGKHAPMISDETW 127 Query: 453 EVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHKD 632 +I KNA +L+S I+ KTLERSYLLK+ +VERPQ MLMRVS+GIH D Sbjct: 128 AIIEKNADKLNSAIVYDRDYSYTYFGFKTLERSYLLKINKEIVERPQQMLMRVSIGIHGD 187 Query: 633 DIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAVI 812 DI SAI TY+LMS+R+ THASPTLFN+GT RPQ+SSCFL+ M +DSI GIYDTLK+CA+I Sbjct: 188 DITSAIETYNLMSERYMTHASPTLFNSGTCRPQMSSCFLLTMSEDSILGIYDTLKQCALI 247 Query: 813 SKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYL 992 SKSAGGIG++VH IRATGS I GTNGTSNG++PMLRV+N+TARYVDQGG KR GAFA+YL Sbjct: 248 SKSAGGIGLNVHKIRATGSVIAGTNGTSNGLIPMLRVYNNTARYVDQGGNKRPGAFAIYL 307 Query: 993 EPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLAD 1172 EPWHADIFEF+ LRKN G EE RARDLF ALW+PDLFM+RV+ +++WS CP E PGL D Sbjct: 308 EPWHADIFEFVSLRKNTGPEEERARDLFLALWIPDLFMKRVEKDQEWSLMCPCECPGLDD 367 Query: 1173 CWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLG 1352 CWG + A+ LW I+ QIETG PY+ YKD+ NRKSNQQNLG Sbjct: 368 CWGEEFEALYAKYEAEGRVRKTVKARKLWEHIVSNQIETGLPYITYKDAANRKSNQQNLG 427 Query: 1353 TIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFD 1532 TIK SNLCTEIIE+++P+E AVCNLASIAL R+V + + FD Sbjct: 428 TIKCSNLCTEIIEYSAPDEIAVCNLASIALNRYV-------------------TPEKKFD 468 Query: 1533 FDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSP 1712 F KL EVT +T NLNKII++NYYPVE AR SNMRHRPIG+GVQGLAD FML+ PF S Sbjct: 469 FVKLAEVTKVITRNLNKIIDVNYYPVEEARNSNMRHRPIGLGVQGLADCFMLMRYPFTSA 528 Query: 1713 EAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNWP 1892 EA+ LN+ IFETIYY GPY TYEGSPVSKG +Q DMW V P+ + +W Sbjct: 529 EARDLNKRIFETIYYAALEASCELAELNGPYSTYEGSPVSKGQLQFDMWGVTPTDQCDWA 588 Query: 1893 TLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLL 2072 TLR+ IAK G+RNSLL+APMPTAST+QILGNNE EPYTSNIYSRRVLSG+F +VN H+L Sbjct: 589 TLRKKIAKHGIRNSLLMAPMPTASTAQILGNNESIEPYTSNIYSRRVLSGDFQIVNPHML 648 Query: 2073 HDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYI 2252 DL E G+WT +KN++I +GSIQ ++ IP D+K +Y+TVWEI QK +++MA DRG YI Sbjct: 649 KDLVERGLWTDEMKNRLIANNGSIQNIDGIPSDIKELYRTVWEISQKDIIEMAADRGAYI 708 Query: 2253 DQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLK 2420 DQSQSLN+HM +P++A +TS+HF+ W KGLKTGMYYLRT+ A +A++FTVD LK Sbjct: 709 DQSQSLNIHMAKPSYAGITSMHFYGWKKGLKTGMYYLRTKPAVNAVQFTVDKNALK 764
>P21524:RIR1_YEAST Ribonucleoside-diphosphate reductase large chain 1 - Saccharomyces| cerevisiae (Baker's yeast) Length = 888 Score = 958 bits (2476), Expect = 0.0 Identities = 462/772 (59%), Positives = 580/772 (75%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 MYV KRDGR E V FDKITAR+ +L YGL +H D V V Q++ +GVY+GVTT +LD Sbjct: 1 MYVYKRDGRKEPVQFDKITARISRLCYGLDPKHIDAVKVTQRIISGVYEGVTTIELDNLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA+LAARIA+SNLHK T K FS+ ++D+Y + N +G +P+I++D+ Sbjct: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVVEDLYRYVNAATGKPAPMISDDV 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 Y ++M+N +L+S I+ KTLERSYLL++ G V ERPQH++MRV++GIH Sbjct: 121 YNIVMENKDKLNSAIVYDRDFQYSYFGFKTLERSYLLRINGQVAERPQHLIMRVALGIHG 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DI++A+ TY+LMS ++FTHASPTLFNAGTP+PQ+SSCFL+ MK+DSIEGIYDTLKECA+ Sbjct: 181 RDIEAALETYNLMSLKYFTHASPTLFNAGTPKPQMSSCFLVAMKEDSIEGIYDTLKECAL 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK+AGGIG+ +HNIR+TGSYI GTNGTSNG++PM+RVFN+TARYVDQGG KR GAFA+Y Sbjct: 241 ISKTAGGIGLHIHNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWHADIF+F+D+RKNHGKEE RARDLF ALW+PDLFM+RV+ N W+ F P APGL+ Sbjct: 301 LEPWHADIFDFIDIRKNHGKEEIRARDLFPALWIPDLFMKRVEENGTWTLFSPTSAPGLS 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 DC+G I AQ LW+ IL+AQ ETGTP+++YKD+CNRKSNQ+NL Sbjct: 361 DCYG-DEFEALYTRYEKEGRGKTIKAQKLWYSILEAQTETGTPFVVYKDACNRKSNQKNL 419 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 G IKSSNLC EI+E+++P+ETAVCNLAS+ALP F+ S K + Sbjct: 420 GVIKSSNLCCEIVEYSAPDETAVCNLASVALPAFIET--------------SEDGKTSTY 465 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 +F KL E+ VT NLN++I+ NYYPVE AR+SNMRHRPI +GVQGLADTFMLL +PFDS Sbjct: 466 NFKKLHEIAKVVTRNLNRVIDRNYYPVEEARKSNMRHRPIALGVQGLADTFMLLRLPFDS 525 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 EA+ LN IFETIY+ GPYET++GSP S+GI+Q DMW+ P W+W Sbjct: 526 EEARLLNIQIFETIYHASMEASCELAQKDGPYETFQGSPASQGILQFDMWDQKPYGMWDW 585 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 TLR+ I K GVRNSL +APMPTASTSQILG NECFEP TSN+YSRRVLSGEF VVN +L Sbjct: 586 DTLRKDIMKHGVRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYL 645 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L DL ++GIW +K +I ++GSIQ + +P +LK +YKTVWEI QKT+++MA DR Y Sbjct: 646 LRDLVDLGIWDEGMKQYLITQNGSIQGLPNVPQELKDLYKTVWEISQKTIINMAADRSVY 705 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVD 2405 IDQS SLN+ + P KLTS+HF+ W KGLKTGMYYLRT+AA+ AI+FT+D Sbjct: 706 IDQSHSLNLFLRAPTMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTID 757
>P21672:RIR3_YEAST Ribonucleoside-diphosphate reductase large chain 2 - Saccharomyces| cerevisiae (Baker's yeast) Length = 869 Score = 946 bits (2445), Expect = 0.0 Identities = 459/772 (59%), Positives = 575/772 (74%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 MYV+KRDGR E V FDKIT+R+ +LSYGL D V V Q++ +GVY GVTT +LD Sbjct: 1 MYVIKRDGRKEPVQFDKITSRITRLSYGLDPNRIDAVKVTQRIISGVYSGVTTVELDNLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA+LAARIA+SNLHK T K FS+ I+D++ N +G +P+I+++I Sbjct: 61 AETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVIEDLHDWINPATGKHAPMISDEI 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 Y ++M+N L+S I+ KTLERSYLL+L G V ERPQH++MRV++GIH Sbjct: 121 YNIVMENKDTLNSAIVYDRDFQYTYFGFKTLERSYLLRLNGEVAERPQHLVMRVALGIHG 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DI+S ++TY+LMS R+FTHASPTLFNAGTP PQ+SSCFLI MKDDSIEGIYDTLKECA+ Sbjct: 181 SDIESVLKTYNLMSLRYFTHASPTLFNAGTPHPQMSSCFLIAMKDDSIEGIYDTLKECAM 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK+AGG+G+ ++NIR+TGSYI GTNGTSNG++PM+RVFN+TARYVDQGG KR GAFA++ Sbjct: 241 ISKTAGGVGLHINNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALF 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWHADIF+F+D+RK HGKEE RARDLF ALW+PDLFM+RVQ + W+ F P+ APGL Sbjct: 301 LEPWHADIFDFVDIRKTHGKEEIRARDLFPALWIPDLFMKRVQEDGPWTLFSPSAAPGLD 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 D WG I AQ LW+ IL+AQ ETGTP+M+YKD+CNRK+NQQNL Sbjct: 361 DVWG-DEFEELYTRYEREGRGKTIKAQKLWYAILQAQTETGTPFMVYKDACNRKTNQQNL 419 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIKSSNLC EI+E++SP+ETAVCNLASIALP FV S K + Sbjct: 420 GTIKSSNLCCEIVEYSSPDETAVCNLASIALPAFVEV--------------SEDGKTASY 465 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 +F++L E+ +T NLN++I+ NYYPV AR SNM+HRPI +GVQGLADT+M+L +PF+S Sbjct: 466 NFERLHEIAKVITHNLNRVIDRNYYPVPEARNSNMKHRPIALGVQGLADTYMMLRLPFES 525 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 EAQ LN+ IFETIY+ G Y T+EGSP SKGI+Q DMWN P W+W Sbjct: 526 EEAQTLNKQIFETIYHATLEASCELAQKEGKYSTFEGSPASKGILQFDMWNAKPFGMWDW 585 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 TLR+ I K G+RNSL +APMPTASTSQILG NECFEP TSN+YSRRVLSGEF VVN +L Sbjct: 586 ETLRKDIVKHGLRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYL 645 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L DL ++GIW ++K +I ++GSIQ + +P +LK +YKTVWEI QKT+++MA DR Y Sbjct: 646 LRDLVDLGIWDDSMKQYLITQNGSIQGLPNVPQELKELYKTVWEISQKTIINMAADRAIY 705 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVD 2405 IDQS SLN+ + P+ K+TS+HF+ W KGLKTGMYYLRT+AA+ AI+FT+D Sbjct: 706 IDQSHSLNLFLQAPSMGKITSMHFYGWKKGLKTGMYYLRTQAASAAIQFTID 757
>P50648:RIR1_PLAF4 Ribonucleoside-diphosphate reductase large chain - Plasmodium| falciparum (isolate Dd2) Length = 806 Score = 940 bits (2429), Expect = 0.0 Identities = 475/824 (57%), Positives = 587/824 (71%), Gaps = 6/824 (0%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 MYV+ R G E + FD+I R+++LSYGL E DP V Q V G+Y G+ T +LD Sbjct: 1 MYVLNRKGEEEDISFDQILKRIQRLSYGL-HELVDPARVTQGVINGMYSGIKTCELDELA 59 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 +HPD++ LAARI NLHKNT +E + +Y Y + G + LI++++ Sbjct: 60 AQTCAYMATTHPDFSILAARITTDNLHKNTSDDVAEVAEALYT-YKDVRGRPASLISKEV 118 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 Y+ I+ + RL+ EI KTLERSYLL++ ++ERPQH+LMRVS+GIH Sbjct: 119 YDFILLHKDRLNKEIDYTRDFNYDYFGFKTLERSYLLRINNKIIERPQHLLMRVSIGIHI 178 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DDID A+ TYHLMSQ++FTHA+PTLFN+GTPRPQ+SSCFL+ MK DSIEGI++TLK+CA+ Sbjct: 179 DDIDKALETYHLMSQKYFTHATPTLFNSGTPRPQMSSCFLLSMKADSIEGIFETLKQCAL 238 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK+AGGIGV+V +IR SYIRGTNG SNG+VPMLRVFNDTARYVDQGGGKRKG+FAVY Sbjct: 239 ISKTAGGIGVAVQDIRGQNSYIRGTNGISNGLVPMLRVFNDTARYVDQGGGKRKGSFAVY 298 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 +EPWH+DIFEFLDLRKNHGKEE RARDLF+A+WVPDLFM+RV+ N++W+ CPNE PGL+ Sbjct: 299 IEPWHSDIFEFLDLRKNHGKEELRARDLFYAVWVPDLFMKRVKENKNWTLMCPNECPGLS 358 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 + WG + AQ LWF IL++QIETG PYMLYKDSCN KSNQ+NL Sbjct: 359 ETWGEEFEKLYTKYEEENMGKKTVLAQDLWFAILQSQIETGVPYMLYKDSCNAKSNQKNL 418 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIK SNLC EIIE+TSP+E AVCNLASIAL +FV + + F Sbjct: 419 GTIKCSNLCCEIIEYTSPDEVAVCNLASIALCKFV------------------DLEKKEF 460 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 +F KL E+T +T NL+KIIE NYYPV+ A+ SN RHRPIGIGVQGLADTFMLL P++S Sbjct: 461 NFKKLYEITKIITRNLDKIIERNYYPVKEAKTSNTRHRPIGIGVQGLADTFMLLRYPYES 520 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNV-VPSTRWN 1886 A++LN+ IFET+YY GPYE+Y+GSP S+GI+Q DMWN V + W+ Sbjct: 521 DAAKELNKRIFETMYYAALEMSVELASIHGPYESYQGSPASQGILQFDMWNAKVDNKYWD 580 Query: 1887 WPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKH 2066 W L+ I K G+RNSLL+APMPTASTSQILGNNE FEPYTSNIY RRVLSGEF VVN H Sbjct: 581 WDELKAKIRKHGLRNSLLLAPMPTASTSQILGNNESFEPYTSNIYYRRVLSGEFFVVNPH 640 Query: 2067 LLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGC 2246 LL DL + G+W +K ++I +GSIQ + EIPDDLK +YKTVWEIKQK ++DMA DRG Sbjct: 641 LLKDLFDRGLWDEDMKQQLIAHNGSIQYISEIPDDLKELYKTVWEIKQKNIIDMAADRGI 700 Query: 2247 YIDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLKVX 2426 +IDQSQSLN+++ +P FAKL+S+HF+ W KGLKTG YYLRT+AA DAIKFTVDT K Sbjct: 701 FIDQSQSLNIYIQKPTFAKLSSMHFYGWEKGLKTGAYYLRTQAATDAIKFTVDTHVAKNA 760 Query: 2427 XXXXXXXXXXXXKLAEED---DEAKMAQVVCSL--NNREECLAC 2543 + + E+ + Q VC L NN E+CL C Sbjct: 761 VKLKNADGVQITREVSRETISTESTVTQNVCPLRRNNDEQCLMC 804
>P32984:RIR1_VARV Ribonucleoside-diphosphate reductase large chain - Variola virus| Length = 771 Score = 915 bits (2365), Expect = 0.0 Identities = 452/777 (58%), Positives = 561/777 (72%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 M+V+KR+G E V FDKIT+R++KL YGL+ +H DP+ +A KV G+Y GVTT +LD Sbjct: 1 MFVIKRNGYKENVMFDKITSRIRKLCYGLNTDHIDPIKIAMKVIQGIYNGVTTVELDTLT 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA LAARIAVSNLHK TKK FSE +KD++ + N ++G SP+I+ Sbjct: 61 AEIAATCTTQHPDYAILAARIAVSNLHKETKKLFSEVMKDLFNYVNPKNGKHSPIISSIT 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 +V+ K +L+S II KTLE+SYLLK+ +VERPQHMLMRV+VGIH+ Sbjct: 121 MDVVNKYKDKLNSVIIYERDFSYNYFGFKTLEKSYLLKINNKIVERPQHMLMRVAVGIHQ 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DIDSAI TY+L+S++WFTHASPTLFNAGT R Q+SSCFL+ M DDSIEGIYDTLK CA+ Sbjct: 181 WDIDSAIETYNLLSEKWFTHASPTLFNAGTSRHQMSSCFLLNMMDDSIEGIYDTLKRCAL 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK AGGIG+S+ NIRA+GSYI GTNG SNGI+PMLRV+N+TARY+DQGG KR G +Y Sbjct: 241 ISKMAGGIGLSISNIRASGSYISGTNGASNGIIPMLRVYNNTARYIDQGGNKRPGVMTIY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWH+DI FLDL+KN G EE+R RDLF ALW+PDLFM+RV+++ +WS CP+E PGL Sbjct: 301 LEPWHSDIMAFLDLKKNTGNEEHRTRDLFIALWIPDLFMKRVKDDGEWSLMCPDECPGLD 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 + WG +I A+ +W I+++QIETGTP++LYKD+CN+KSNQQNL Sbjct: 361 NVWGDEFERLYTLYEREKRYKSIIKARVVWKAIIESQIETGTPFILYKDACNKKSNQQNL 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIK SNLCTEII++ E AVCNLASIAL FV + F Sbjct: 421 GTIKCSNLCTEIIQYADANEVAVCNLASIALNMFVID--------------------GQF 460 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF KL +V + NLNKII++NYYP+ A SN RHRPIGIGVQGLAD F+LL PFDS Sbjct: 461 DFLKLKDVVKVIVRNLNKIIDINYYPIPEAEISNKRHRPIGIGVQGLADAFILLNYPFDS 520 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 EAQ LN+ IFETIYY GPY+TY GS S GI+Q D+WNVVPS WNW Sbjct: 521 LEAQDLNKKIFETIYYGALEASCELAEKEGPYDTYVGSYASNGILQYDLWNVVPSDLWNW 580 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L++ I G+RNSLLVAPMPTAST+QILGNNE EPYTSNIY+RRVLSGEF VVN HL Sbjct: 581 EPLKDKIRTYGLRNSLLVAPMPTASTAQILGNNESVEPYTSNIYTRRVLSGEFQVVNPHL 640 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L LTE +W +KN+I+ + GSIQ +P+D+K +YKT+WEI QKT++ MA DRG + Sbjct: 641 LRVLTERKLWNDEIKNRIMVDGGSIQN-TNLPEDIKRVYKTIWEIPQKTIIKMAADRGAF 699 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLK 2420 IDQSQS+N+H+ P+++KLTS+HF+ WS GLKTGMYYLRT+ A+ I+FT+D +K Sbjct: 700 IDQSQSMNIHIADPSYSKLTSMHFYGWSLGLKTGMYYLRTKPASAPIQFTLDKDKIK 756
>P12848:RIR1_VACCV Ribonucleoside-diphosphate reductase large chain - Vaccinia virus| (strain Western Reserve / WR) (VACV) Length = 771 Score = 912 bits (2358), Expect = 0.0 Identities = 450/777 (57%), Positives = 562/777 (72%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 M+V+KR+G E V FDKIT+R++KL YGL+ +H DP+ +A KV G+Y GVTT +LD Sbjct: 1 MFVIKRNGYKENVMFDKITSRIRKLCYGLNTDHIDPIKIAMKVIQGIYNGVTTVELDTLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA LAARIAVSNLHK TKK FSE ++D++ + N ++G SP+I+ Sbjct: 61 AEIAATCTTQHPDYAILAARIAVSNLHKETKKLFSEVMEDLFNYVNPKNGKHSPIISSIT 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 +++ K +L+S II KTLE+SYLLK+ +VERPQHMLMRV+VGIH+ Sbjct: 121 MDIVNKYKDKLNSVIIYERDFSYNYFGFKTLEKSYLLKINNKIVERPQHMLMRVAVGIHQ 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DIDSAI TY+L+S++WFTHASPTLFNAGT R Q+SSCFL+ M DDSIEGIYDTLK CA+ Sbjct: 181 WDIDSAIETYNLLSEKWFTHASPTLFNAGTSRHQMSSCFLLNMIDDSIEGIYDTLKRCAL 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK AGGIG+S+ NIRA+GSYI GTNG SNGI+PMLRV+N+TARY+DQGG KR G A+Y Sbjct: 241 ISKMAGGIGLSISNIRASGSYISGTNGISNGIIPMLRVYNNTARYIDQGGNKRPGVMAIY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWH+DI FLDL+KN G EE+R RDLF ALW+PDLFM+RV+++ +WS CP+E PGL Sbjct: 301 LEPWHSDIMAFLDLKKNTGNEEHRTRDLFIALWIPDLFMKRVKDDGEWSLMCPDECPGLD 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 + WG +I A+ +W I+++QIETGTP++LYKD+CN+KSNQQNL Sbjct: 361 NVWGDEFERLYTLYERERRYKSIIKARVVWKAIIESQIETGTPFILYKDACNKKSNQQNL 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIK SNLCTEII++ E AVCNLAS+AL FV + F Sbjct: 421 GTIKCSNLCTEIIQYADANEVAVCNLASVALNMFVID--------------------GRF 460 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF KL +V + NLNKII++NYYP+ A SN RHRPIGIGVQGLAD F+LL PFDS Sbjct: 461 DFLKLKDVVKVIVRNLNKIIDINYYPIPEAEISNKRHRPIGIGVQGLADAFILLNYPFDS 520 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 EAQ LN+ IFETIYY GPY+TY GS S GI+Q D+WNVVPS WNW Sbjct: 521 LEAQDLNKKIFETIYYGALEASCELAEKEGPYDTYVGSYASNGILQYDLWNVVPSDLWNW 580 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L++ I G+RNSLLVAPMPTAST+QILGNNE EPYTSNIY+RRVLSGEF VVN HL Sbjct: 581 EPLKDKIRTYGLRNSLLVAPMPTASTAQILGNNESVEPYTSNIYTRRVLSGEFQVVNPHL 640 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L LTE +W +KN+I+ + GSIQ +P+D+K +YKT+WEI QKT++ MA DRG + Sbjct: 641 LRVLTERKLWNDEIKNRIMADGGSIQN-TNLPEDIKRVYKTIWEIPQKTIIKMAADRGAF 699 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLK 2420 IDQSQS+N+H+ P+++KLTS+HF+ WS GLKTGMYYLRT+ A+ I+FT+D +K Sbjct: 700 IDQSQSMNIHIADPSYSKLTSMHFYGWSLGLKTGMYYLRTKPASAPIQFTLDKDKIK 756
>P20503:RIR1_VACCC Ribonucleoside-diphosphate reductase large chain - Vaccinia virus| (strain Copenhagen) (VACV) Length = 771 Score = 912 bits (2358), Expect = 0.0 Identities = 450/777 (57%), Positives = 562/777 (72%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 M+V+KR+G E V FDKIT+R++KL YGL+ +H DP+ +A KV G+Y GVTT +LD Sbjct: 1 MFVIKRNGYKENVMFDKITSRIRKLCYGLNTDHIDPIKIAMKVIQGIYNGVTTVELDTLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA LAARIAVSNLHK TKK FSE ++D++ + N ++G SP+I+ Sbjct: 61 AEIAATCTTQHPDYAILAARIAVSNLHKETKKLFSEVMEDLFNYVNPKNGKHSPIISSIT 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 +++ K +L+S II KTLE+SYLLK+ +VERPQHMLMRV+VGIH+ Sbjct: 121 MDIVNKYKDKLNSVIIYERDFSYNYFGFKTLEKSYLLKINNKIVERPQHMLMRVAVGIHQ 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DIDSAI TY+L+S++WFTHASPTLFNAGT R Q+SSCFL+ M DDSIEGIYDTLK CA+ Sbjct: 181 WDIDSAIETYNLLSEKWFTHASPTLFNAGTSRHQMSSCFLLNMIDDSIEGIYDTLKRCAL 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK AGGIG+S+ NIRA+GSYI GTNG SNGI+PMLRV+N+TARY+DQGG KR G A+Y Sbjct: 241 ISKMAGGIGLSISNIRASGSYISGTNGISNGIIPMLRVYNNTARYIDQGGNKRPGVMAIY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWH+DI FLDL+KN G EE+R RDLF ALW+PDLFM+RV+++ +WS CP+E PGL Sbjct: 301 LEPWHSDIMAFLDLKKNTGNEEHRTRDLFIALWIPDLFMKRVKDDGEWSLMCPDECPGLD 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 + WG +I A+ +W I+++QIETGTP++LYKD+CN+KSNQQNL Sbjct: 361 NVWGDEFERLYTLYERERRYKSIIKARVVWKAIIESQIETGTPFILYKDACNKKSNQQNL 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIK SNLCTEII++ E AVCNLAS+AL FV + F Sbjct: 421 GTIKCSNLCTEIIQYADANEVAVCNLASVALNMFVID--------------------GRF 460 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF KL +V + NLNKII++NYYP+ A SN RHRPIGIGVQGLAD F+LL PFDS Sbjct: 461 DFLKLKDVVKVIVRNLNKIIDINYYPIPEAEISNKRHRPIGIGVQGLADAFILLNYPFDS 520 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 EAQ LN+ IFETIYY GPY+TY GS S GI+Q D+WNVVPS WNW Sbjct: 521 LEAQDLNKKIFETIYYGALEASCELAEKEGPYDTYVGSYASNGILQYDLWNVVPSDLWNW 580 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L++ I G+RNSLLVAPMPTAST+QILGNNE EPYTSNIY+RRVLSGEF VVN HL Sbjct: 581 EPLKDKIRTYGLRNSLLVAPMPTASTAQILGNNESVEPYTSNIYTRRVLSGEFQVVNPHL 640 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L LTE +W +KN+I+ + GSIQ +P+D+K +YKT+WEI QKT++ MA DRG + Sbjct: 641 LRVLTERKLWNDEIKNRIMADGGSIQN-TNLPEDIKRVYKTIWEIPQKTIIKMAADRGAF 699 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLK 2420 IDQSQS+N+H+ P+++KLTS+HF+ WS GLKTGMYYLRT+ A+ I+FT+D +K Sbjct: 700 IDQSQSMNIHIADPSYSKLTSMHFYGWSLGLKTGMYYLRTKPASAPIQFTLDKDKIK 756
>Q76RD8:RIR1_VACCA Ribonucleoside-diphosphate reductase large chain - Vaccinia virus| (strain Ankara) (VACV) Length = 771 Score = 912 bits (2358), Expect = 0.0 Identities = 450/777 (57%), Positives = 562/777 (72%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 M+V+KR+G E V FDKIT+R++KL YGL+ +H DP+ +A KV G+Y GVTT +LD Sbjct: 1 MFVIKRNGYKENVMFDKITSRIRKLCYGLNTDHIDPIKIAMKVIQGIYNGVTTVELDTLA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 HPDYA LAARIAVSNLHK TKK FSE ++D++ + N ++G SP+I+ Sbjct: 61 AEIAATCTTQHPDYAILAARIAVSNLHKETKKLFSEVMEDLFNYVNPKNGKHSPIISSIT 120 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 +++ K +L+S II KTLE+SYLLK+ +VERPQHMLMRV+VGIH+ Sbjct: 121 MDIVNKYKDKLNSVIIYERDFSYNYFGFKTLEKSYLLKINNKIVERPQHMLMRVAVGIHQ 180 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DIDSAI TY+L+S++WFTHASPTLFNAGT R Q+SSCFL+ M DDSIEGIYDTLK CA+ Sbjct: 181 WDIDSAIETYNLLSEKWFTHASPTLFNAGTSRHQMSSCFLLNMIDDSIEGIYDTLKRCAL 240 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK AGGIG+S+ NIRA+GSYI GTNG SNGI+PMLRV+N+TARY+DQGG KR G A+Y Sbjct: 241 ISKMAGGIGLSISNIRASGSYISGTNGISNGIIPMLRVYNNTARYIDQGGNKRPGVMAIY 300 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWH+DI FLDL+KN G EE+R RDLF ALW+PDLFM+RV+++ +WS CP+E PGL Sbjct: 301 LEPWHSDIMAFLDLKKNTGNEEHRTRDLFIALWIPDLFMKRVKDDGEWSLMCPDECPGLD 360 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 + WG +I A+ +W I+++QIETGTP++LYKD+CN+KSNQQNL Sbjct: 361 NVWGDEFERLYTLYERERRYKSIIKARVVWKAIIESQIETGTPFILYKDACNKKSNQQNL 420 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIK SNLCTEII++ E AVCNLAS+AL FV + F Sbjct: 421 GTIKCSNLCTEIIQYADANEVAVCNLASVALNMFVID--------------------GRF 460 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF KL +V + NLNKII++NYYP+ A SN RHRPIGIGVQGLAD F+LL PFDS Sbjct: 461 DFLKLKDVVKVIVRNLNKIIDINYYPIPEAEISNKRHRPIGIGVQGLADAFILLNYPFDS 520 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNW 1889 EAQ LN+ IFETIYY GPY+TY GS S GI+Q D+WNVVPS WNW Sbjct: 521 LEAQDLNKKIFETIYYGALEASCELAEKEGPYDTYVGSYASNGILQYDLWNVVPSDLWNW 580 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L++ I G+RNSLLVAPMPTAST+QILGNNE EPYTSNIY+RRVLSGEF VVN HL Sbjct: 581 EPLKDKIRTYGLRNSLLVAPMPTASTAQILGNNESVEPYTSNIYTRRVLSGEFQVVNPHL 640 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCY 2249 L LTE +W +KN+I+ + GSIQ +P+D+K +YKT+WEI QKT++ MA DRG + Sbjct: 641 LRVLTERKLWNDEIKNRIMADGGSIQN-TNLPEDIKRVYKTIWEIPQKTIIKMAADRGAF 699 Query: 2250 IDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLK 2420 IDQSQS+N+H+ P+++KLTS+HF+ WS GLKTGMYYLRT+ A+ I+FT+D +K Sbjct: 700 IDQSQSMNIHIADPSYSKLTSMHFYGWSLGLKTGMYYLRTKPASAPIQFTLDKDKIK 756
>O61065:RIR1_CRYPV Ribonucleoside-diphosphate reductase large chain - Cryptosporidium| parvum Length = 803 Score = 905 bits (2339), Expect = 0.0 Identities = 452/821 (55%), Positives = 576/821 (70%), Gaps = 3/821 (0%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 MYVV R G E V FD+I +R+ KLSYGL DP V Q V G+Y G+ TS+LD Sbjct: 1 MYVVNRKGEEEPVSFDQILSRITKLSYGL-HPLVDPARVTQAVINGLYSGIKTSELDELA 59 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 +H D++ LAARI+ SNLHKNT + +Y ++ + G +PLI++ + Sbjct: 60 SQTCAYMAATHNDFSKLAARISTSNLHKNTSSDIGDVASQLY-NFKDNQGCPAPLISKPV 118 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 Y+ IM+N R++S+I KTLERSYLLK+ VVERPQH+LMRVS GIH Sbjct: 119 YDFIMENRERINSKIDFSKDFEYDYFAFKTLERSYLLKIDNKVVERPQHLLMRVSCGIHC 178 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DI++A+ TY L+SQ++FTHA+PTLFN+GTPRPQ+SSCFL+ + +DSI GI+DTL +CA Sbjct: 179 GDIEAALETYELLSQKYFTHATPTLFNSGTPRPQMSSCFLLRIPEDSINGIFDTLTKCAN 238 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK+AGG+GV+V NIR TGSYIRGTNG SNG++PMLRV+NDTARY+DQGGGKRKGA A+Y Sbjct: 239 ISKTAGGLGVAVSNIRGTGSYIRGTNGRSNGLIPMLRVYNDTARYIDQGGGKRKGAIAIY 298 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 LEPWH D+ EF+++RKNHGKEE R RDLF ALWVPDLFM+RV+ ++DW+ CP+E GL Sbjct: 299 LEPWHVDVVEFIEIRKNHGKEEMRCRDLFPALWVPDLFMERVEKDQDWTLMCPDECRGLQ 358 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 D WG + AQ LWF IL+AQIETGTP++ YKD+ N KSNQ+NL Sbjct: 359 DVWGDDFKKLYEEYEKQGRGRKTMKAQKLWFLILQAQIETGTPFICYKDAANSKSNQKNL 418 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTI SSNLCTEIIE+TS +E AVCNLASI LP+FV N+ F Sbjct: 419 GTIVSSNLCTEIIEYTSTDEVAVCNLASIGLPKFV------------------DKNNKTF 460 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DFDKL EVT +T NLNK+I++ YY ++ ++SN+RHRP+GIG+QGLAD FM+L MP++S Sbjct: 461 DFDKLKEVTKVITRNLNKLIDVGYYSLKECKKSNLRHRPLGIGIQGLADCFMMLRMPYES 520 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVP-STRWN 1886 A++LN+ IFE IYY GPYETY GSP SKGI+Q DMW V P S + Sbjct: 521 EGAKKLNKQIFEVIYYAALDASCELAEKYGPYETYSGSPASKGILQFDMWGVTPDSGLCD 580 Query: 1887 WPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKH 2066 W L++ I+K G+RNSLL++PMPTASTSQILGNNE FEP+TSNIY RRVLSGEF VVN H Sbjct: 581 WDLLKDRISKHGIRNSLLISPMPTASTSQILGNNESFEPFTSNIYHRRVLSGEFFVVNPH 640 Query: 2067 LLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGC 2246 LL+DL E+G+W LK II +GSIQ + IP+D++ +YKTVWEIKQKT++DMA DRG Sbjct: 641 LLNDLLELGLWDDRLKQNIIANNGSIQNILTIPEDIRELYKTVWEIKQKTVIDMAADRGP 700 Query: 2247 YIDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLKVX 2426 Y+ QSQSLN+HM+ NFAKL+S+HF+ W KGLKTG+YYLRT++A I+FTVD LK Sbjct: 701 YVCQSQSLNIHMENANFAKLSSMHFYGWKKGLKTGIYYLRTQSATRPIQFTVDQQLLKSE 760 Query: 2427 XXXXXXXXXXXXKLAEEDDEAKMAQVV--CSLNNREECLAC 2543 + E + + +A + ++ + EEC+ C Sbjct: 761 TKEKDSLETNKRQALEPEAQKLIACPLRPTNMKDDEECMMC 801
>P50647:RIR1_PLAFG Ribonucleoside-diphosphate reductase large chain - Plasmodium| falciparum (isolate FCR-3 / Gambia) Length = 804 Score = 902 bits (2331), Expect = 0.0 Identities = 461/823 (56%), Positives = 576/823 (69%), Gaps = 5/823 (0%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 MYV+ R G E + FD+I R+++LSYGL + P V Q V G+Y + T +LD Sbjct: 1 MYVLNRKGEEEDISFDQILKRIQRLSYGLHKLGEYPACVTQGVINGMYSSIKTCELDELA 60 Query: 270 XXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDI 449 +HPD++ LAARI NLHKNT +E + +Y Y + G + LI++++ Sbjct: 61 AQTCAYMATTHPDFSILAARITTDNLHKNTSDDVAEVAEALYT-YKDGRGRPASLISKEV 119 Query: 450 YEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHK 629 Y+ I+ + RL+ EI KTLERSYLL++ ++ERPQH+LMRVS+GIH Sbjct: 120 YDFILLHKVRLNKEIDYTTHFNYDYFGFKTLERSYLLRINNKIIERPQHLLMRVSIGIHI 179 Query: 630 DDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAV 809 DDID A+ TYHLMSQ++FTHA+PTLFN+GTPRPQ+SSCFL+ MK DSIEGI++TLK+CA+ Sbjct: 180 DDIDKALETYHLMSQKYFTHATPTLFNSGTPRPQMSSCFLLSMKADSIEGIFETLKQCAL 239 Query: 810 ISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVY 989 ISK+AGGIGV+V +IR SYIRGTNG SNG+VPMLRVFNDTARYVDQGGGKRKG++AVY Sbjct: 240 ISKTAGGIGVAVQDIRGQNSYIRGTNGISNGLVPMLRVFNDTARYVDQGGGKRKGSYAVY 299 Query: 990 LEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLA 1169 +EPWH+DIFEFLDLRKNHGKEE RARDLF+A+WVPDLFM+RV+ N++W+ CPNE PGL+ Sbjct: 300 IEPWHSDIFEFLDLRKNHGKEELRARDLFYAVWVPDLFMKRVKENKNWTLMCPNECPGLS 359 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 + WG + AQ LWF IL++QIETG P LYKDSCN K +NL Sbjct: 360 ETWGEEFEKLYTKYEEENMGKKTVLAQDLWFAILQSQIETGVPIYLYKDSCNAKP-IKNL 418 Query: 1350 GTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 GTIK SNLC EIIE+TSP+E AVCNLASIAL +FV + + F Sbjct: 419 GTIKCSNLCCEIIEYTSPDEVAVCNLASIALCKFV------------------DLEKKEF 460 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 +F KL E+T +T NL+KIIE NYYPV+ A+ SN RHRPIGIGVQGLADTFMLL ++S Sbjct: 461 NFKKLYEITKIITRNLDKIIERNYYPVKEAKTSNTRHRPIGIGVQGLADTFMLLRYLYES 520 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNV-VPSTRWN 1886 A++LN+ I+ET+YY GPYE+Y+GSP S+GI+Q DMWN V + W+ Sbjct: 521 DAAKELNKRIYETMYY-AALEMSVDWLQSGPYESYQGSPGSQGILQFDMWNAKVDNKYWD 579 Query: 1887 WPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKH 2066 W L+ IAK G+RN LL+APMPTASTSQILGNNE FEPYTSNIY RRVLSGEF VVN H Sbjct: 580 WDELKLKIAKTGLRNLLLLAPMPTASTSQILGNNESFEPYTSNIYYRRVLSGEFFVVNPH 639 Query: 2067 LLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGC 2246 LL DL + G+W +K ++I +GSIQ + EIPDDLK +YKTVWEIKQK ++DMA DRG Sbjct: 640 LLKDLFDRGLWDEDMKQQLIAHNGSIQYISEIPDDLKELYKTVWEIKQKNIIDMAADRGY 699 Query: 2247 YIDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLK-V 2423 +IDQSQSLN+++ +P FAKL+S+HF+ W KGLKTG YYLRT+AA DAIKFTVDT K Sbjct: 700 FIDQSQSLNIYIQKPTFAKLSSMHFYGWEKGLKTGAYYLRTQAATDAIKFTVDTHVAKNA 759 Query: 2424 XXXXXXXXXXXXXKLAEEDDEAKMAQVVC---SLNNREECLAC 2543 +++ E + C NN E+CL C Sbjct: 760 VKLKNADGVQITREVSRETIQLNQRYSKCVSFKSNNDEQCLMC 802
>O15909:RIR1_TRYBB Ribonucleoside-diphosphate reductase large chain - Trypanosoma brucei| brucei Length = 838 Score = 837 bits (2162), Expect = 0.0 Identities = 427/793 (53%), Positives = 551/793 (69%), Gaps = 18/793 (2%) Frame = +3 Query: 96 VVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXXXX 275 V KRDG E + +R+ L G+ + D + + V GV +G++TS LD Sbjct: 8 VTKRDGSVEPYDEKVVRSRIVNLMSGIDSYYVDVDDLVRVVGEGVREGMSTSMLDELLAE 67 Query: 276 XXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDIYE 455 HPDY LA R+AV+ LHK T +S ++ + ++ H ++ + +PLI+E++++ Sbjct: 68 TAAYCVTKHPDYGLLAGRLAVTALHKTTTESVLDSFRVLHEHVSQATKRHAPLISEELWD 127 Query: 456 VIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLG---GV--VVERPQHMLMRVSVG 620 + K++A L I KTLERSYLL++ GV VVERPQ M +RV++G Sbjct: 128 IANKHSAALQQIINYERDFDFEYFGYKTLERSYLLRVHKGRGVMEVVERPQQMFLRVALG 187 Query: 621 IHKDDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKE 800 IH +D++ TY MSQ +FTHA+PTLFNAGTP PQ+SSCFL+ M++DSI+GIYDTLK+ Sbjct: 188 IHGEDLERVKETYDYMSQGFFTHATPTLFNAGTPFPQMSSCFLVAMREDSIDGIYDTLKQ 247 Query: 801 CAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAF 980 CA+ISKSAGGIG+ +HNIRA GSYI GTNGTSNG+VPMLRV+N+TARYVDQGGGKRKGAF Sbjct: 248 CAIISKSAGGIGIHMHNIRAAGSYIAGTNGTSNGLVPMLRVWNNTARYVDQGGGKRKGAF 307 Query: 981 AVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAP 1160 A+YLEPWHADIF FL L+KN GKE+ RARDLF+ LW+PDLFM+RV+++ W+ PN AP Sbjct: 308 AIYLEPWHADIFGFLLLKKNTGKEDQRARDLFYGLWIPDLFMERVESHGTWTLMDPNTAP 367 Query: 1161 GLADCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQ 1340 L+DC+G I AQ LWF IL++Q+ETG P+MLYKD+CN KSNQ Sbjct: 368 FLSDCYGQEFTDLYERYEREGRGVRTIQAQELWFLILESQVETGVPFMLYKDACNFKSNQ 427 Query: 1341 QNLGTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKN 1520 +NLGTIK SNLCTEI+E+TS +E AVCNLASIALPRFV K+ Sbjct: 428 KNLGTIKCSNLCTEIVEYTSRDEVAVCNLASIALPRFV--------------------KD 467 Query: 1521 RYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMP 1700 FD+ L EVT VT NLN++I+ N+YPV AR SN+RHRP+GIGVQGLAD F LL +P Sbjct: 468 GAFDYVALKEVTKVVTRNLNRVIDRNHYPVCEARYSNLRHRPVGIGVQGLADAFALLSLP 527 Query: 1701 FDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTR 1880 F PEA++LNR IFETIY GPYET++GSP S+G +Q D+W+ R Sbjct: 528 FAHPEAKKLNRQIFETIYIAAVEASTELAEKDGPYETFKGSPASEGKLQFDLWDEERRIR 587 Query: 1881 -------------WNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIY 2021 W+W +L+E + KVG+RNSLL+APMPTASTSQILGNNEC EP+TSNIY Sbjct: 588 GMNEDSVHSHCGLWDWDSLKERVVKVGMRNSLLIAPMPTASTSQILGNNECIEPFTSNIY 647 Query: 2022 SRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWE 2201 RRVLSGEF VVNKHL+ +L + +W ++ KII +GS+ ++EIP+ ++ +YK VWE Sbjct: 648 VRRVLSGEFPVVNKHLVKELIRLRLWNDDMRRKIIALNGSVSGIKEIPERIRELYKVVWE 707 Query: 2202 IKQKTLVDMAVDRGCYIDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAA 2381 I+QK L+DMA DRG YIDQSQSLN+ + P ++LTS+HF++W KGLKTGMYYLR++ AA Sbjct: 708 IRQKDLIDMAADRGRYIDQSQSLNLFLATPTSSQLTSMHFYSWKKGLKTGMYYLRSQPAA 767 Query: 2382 DAIKFTVDTGFLK 2420 DAIKFT+D +K Sbjct: 768 DAIKFTLDPKAMK 780
>Q8SR37:RIR1_ENCCU Ribonucleoside-diphosphate reductase large chain - Encephalitozoon| cuniculi Length = 768 Score = 728 bits (1880), Expect = 0.0 Identities = 361/764 (47%), Positives = 505/764 (66%) Frame = +3 Query: 114 RTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXXXXXXXXXX 293 ++E + D I +R++ L H D + +++ +G + +T + Sbjct: 11 KSEKLGIDLIRSRIEGYVKDLKLRHVDVDELVERIVSGWCEDMTRKETIDYCSETAASMI 70 Query: 294 XSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDIYEVIMKNA 473 HP+Y +++RI VS +H+ T SF E IK + H +++E++Y +I+++ Sbjct: 71 TKHPEYGQISSRIIVSYIHEITMDSFVEKIKYIQKHRG--------MVSEEMYGIILEHG 122 Query: 474 ARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIHKDDIDSAIR 653 ++ I TL +SYL+K+G ++ERPQ M MRV++ IHK D + Sbjct: 123 ETIEGMINYENDFLFSYFGILTLMKSYLIKVGEEIIERPQDMFMRVALQIHKTDFEKVRE 182 Query: 654 TYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGI 833 Y+L+S +FTHA+PTL+N+ PQL+SCFLI ++DSIEG+Y + + A+I+K +GGI Sbjct: 183 VYNLLSGHYFTHATPTLYNSCLKNPQLASCFLITPREDSIEGVYHMINQAAIITKYSGGI 242 Query: 834 GVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADI 1013 G+++H IR+ GS +R T G SNGI+P+++V N T RY++QG +R G+ A++LEPWH +I Sbjct: 243 GLNLHGIRSKGSSLRSTGGRSNGIIPLIQVLNATKRYINQGAERRPGSIAIFLEPWHMEI 302 Query: 1014 FEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLADCWGXXXX 1193 F+FL+LRKN G EE RARD+F ALW+ DLFM+RV+NNE+WS FCP++A GL+D WG Sbjct: 303 FDFLELRKNTGPEEFRARDIFTALWINDLFMERVKNNEEWSLFCPSQAVGLSDVWGEEFN 362 Query: 1194 XXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNL 1373 V+PAQ LW I++AQIETGTPYM YKD+CNR SNQQ+LGTIKSSNL Sbjct: 363 ALYCKYEKTISRT-VVPAQKLWKAIIEAQIETGTPYMCYKDACNRLSNQQHLGTIKSSNL 421 Query: 1374 CTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEV 1553 C EI+E++S EET+VCNLASI LP FV K+ +FDF+ V Sbjct: 422 CAEIVEYSSGEETSVCNLASICLPMFV--------------------KDGWFDFEAFRRV 461 Query: 1554 TSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNR 1733 +T NLN++I+ NYYPVE ARRSNMR+RPIGIGVQGLAD F +L + F+S A+ LN+ Sbjct: 462 VKILTVNLNRVIDFNYYPVEEARRSNMRNRPIGIGVQGLADLFAILRLAFESDGARSLNQ 521 Query: 1734 DIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNWPTLRETIA 1913 DIFE +YY GP+ +YEGSP+SKGI ++ S W+W LRE I Sbjct: 522 DIFEAMYYSAMEASCELAEKEGPFPSYEGSPISKGIFHFELAGRKASGNWDWEGLRERIR 581 Query: 1914 KVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMG 2093 + GVRNSLL+A MPTA TSQI GNNE FEP+ SNIY+RR +GEF +VN+HL++DL +G Sbjct: 582 RHGVRNSLLIALMPTAGTSQIFGNNEAFEPHASNIYTRRTHAGEFQIVNQHLVNDLVRLG 641 Query: 2094 IWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLN 2273 +W+ +KN +I +GSIQ + IP +++ IYKT WEIK K+++D+A DR ++DQSQSLN Sbjct: 642 LWSYEMKNLVIENEGSIQNITSIPHEIREIYKTAWEIKMKSVIDLAADRQVFVDQSQSLN 701 Query: 2274 VHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVD 2405 + + +P +++LTS+HF+ + GLKTGMYYLRTR AIKFTVD Sbjct: 702 IFIAKPTYSQLTSMHFYGYHCGLKTGMYYLRTRPITSAIKFTVD 745
>Q7T6Y8:RIR1_MIMIV Ribonucleoside-diphosphate reductase large chain - Mimivirus| Length = 881 Score = 655 bits (1690), Expect = 0.0 Identities = 341/776 (43%), Positives = 486/776 (62%), Gaps = 5/776 (0%) Frame = +3 Query: 108 DGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXXXXXXXX 287 +G + + + I ++K+ + H D + + + + T +D Sbjct: 75 NGSIQVITSEIIRTYVEKIFEKMEVTHLDIDKMTKNIFPKLKSINTIKDIDNQIISTASE 134 Query: 288 XXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDIYEVIMK 467 H DY +A I ++NLH NT F ET + +Y + +E S +P+I+E+IY I K Sbjct: 135 MVTDHYDYPKIAVWILMTNLHDNTSDDFLETAEKLYNNKSE-SNKNAPIISENIYNFIKK 193 Query: 468 NAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRVSVGIH--KDDID 641 + ++ I +TLE+SYL ++ +VERPQH+ MRV++ +H K+D+D Sbjct: 194 HIKEINRVIRYDRDYNLTIFGFRTLEKSYLKRINKKIVERPQHLFMRVAITLHYRKNDLD 253 Query: 642 SAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAVISKS 821 TY +S+ +FTHA+PTLFNAGT QLSSCFL+ + DS+E I + KECA+ISK Sbjct: 254 RIFETYKYLSKGYFTHATPTLFNAGTTHEQLSSCFLLGI-GDSLEEISECWKECALISKH 312 Query: 822 AGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPW 1001 AGGIG+ + NIR G+YI T G + G+ +L +FND +RY +QGG KR G+FA+++EPW Sbjct: 313 AGGIGIHMTNIRVEGAYIASTQGEAGGL-RVLTIFNDISRYANQGG-KRPGSFAIFIEPW 370 Query: 1002 HADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEAPGLADCWG 1181 H DIF FLDL+KN G E RARDLF L + D+FM+RV ++ WS CP++ P L + +G Sbjct: 371 HGDIFFFLDLKKNTGAETERARDLFLGLMINDIFMERVYKDDVWSLMCPSQCPNLLNKYG 430 Query: 1182 XXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIK 1361 I A LWF I+++QIETG PY+++KD+ N KSNQ N+G + Sbjct: 431 DEFTKEYLKYESEGIYLKQIRAIDLWFKIMESQIETGVPYVMFKDAINDKSNQINIGVVN 490 Query: 1362 SSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDK 1541 SNLC EI+E + +VCNL+SI LPRFV+ I+ P+ F++ K Sbjct: 491 GSNLCCEIVEVSDKNNFSVCNLSSICLPRFVKI----IDEVPT------------FNYQK 534 Query: 1542 LGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQ 1721 L +++ +T NLN II++N+YP++ R +N+R RPIGIGVQGLAD F + PFDS A+ Sbjct: 535 LFKISRILTRNLNNIIDINFYPLDKTRITNLRDRPIGIGVQGLADVFAMFKTPFDSEIAR 594 Query: 1722 QLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPST---RWNWP 1892 LNR IFETIYY G Y+TY+GSP+S+G Q D+WN S W+W Sbjct: 595 DLNRKIFETIYYGALTESNKLAREFGTYQTYQGSPISQGKFQFDLWNFDKSQLSGMWDWE 654 Query: 1893 TLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLL 2072 LR+ I GVRNSL+ MPTASTSQI+G NEC EPYT NIYSR ++GE+ V+NKHL+ Sbjct: 655 LLRQEILNHGVRNSLVTTCMPTASTSQIMGWNECIEPYTENIYSRSTMAGEYFVINKHLI 714 Query: 2073 HDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYI 2252 DL E+G+W + + I Y GS+ + IPD++KAIY+TVWEI QK++++MA DR ++ Sbjct: 715 KDLIELGVWNSEMVDLIKYYKGSVANIPNIPDNIKAIYRTVWEIPQKSIIEMAADRAPFV 774 Query: 2253 DQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTGFLK 2420 DQ+QS+N+++D+P+FA+L S F+AW KGLKTGMYYLR++ A+ A +F +D +K Sbjct: 775 DQTQSMNLYIDKPSFARLNSCLFYAWRKGLKTGMYYLRSKPASSANQFGIDIDKIK 830
>P42491:RIR1_ASFB7 Ribonucleoside-diphosphate reductase large chain - African swine| fever virus (strain BA71V) (ASFV) Length = 778 Score = 457 bits (1176), Expect = e-127 Identities = 287/734 (39%), Positives = 402/734 (54%), Gaps = 47/734 (6%) Frame = +3 Query: 300 HPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDIYEVIMKNAAR 479 H DY++LAAR++V LH++T SFS+ ++ L + LSP + +Y K A Sbjct: 48 HYDYSTLAARLSVYQLHQSTASSFSKAVR---LQAAQSCSRLSPQFVDVVY----KYKAI 100 Query: 480 LDSEIIXXXXXXXXXXXXKTLERSYLLK-LGGVVVERPQHMLMRVSVGIHKD----DIDS 644 DS I +T++ SYLLK GV++ERPQ MRV++ I+ +I Sbjct: 101 FDSYIDYNRDYKLSLLGIETMKNSYLLKNKDGVIMERPQDAYMRVAIMIYGMGKVVNIKM 160 Query: 645 AIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAVISKSA 824 + TY L+S+ THASPT+FNAGT +PQLSSCFL+ + +D++E +YD +K +IS Sbjct: 161 ILLTYDLLSRHVITHASPTMFNAGTKKPQLSSCFLLNV-NDNLENLYDMVKTAGIISGGG 219 Query: 825 GGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWH 1004 GGIG+ + IRA S+I G+ SNGI + + N + Y +QGG R GA+AVYLE WH Sbjct: 220 GGIGLCLSGIRAKNSFISGSGLRSNGIQNYIMLQNASQCYANQGG-LRPGAYAVYLELWH 278 Query: 1005 ADIFEFLDLRKNHGK---EENRARDLFFALWVPDLFMQ----RVQNNED--WSPFCPNEA 1157 DIF FL + + G+ + A +L + LWVPDLFM+ ++ N D W F P++A Sbjct: 279 QDIFTFLQMPRLKGQMAEQRLNAPNLKYGLWVPDLFMEILEDQIHNRGDGTWYLFSPDQA 338 Query: 1158 PGLADCWGXXXXXXXXXXXXXXXXXX----------VIPAQTLWFDILKAQIETGTPYML 1307 P L + V A+ + + K I+ G PY+ Sbjct: 339 PNLHKVFDLERSQHENAHREFKKLYYQYVAEKRYTGVTTAKEIIKEWFKTVIQVGNPYIG 398 Query: 1308 YKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSP------EETAVCNLASIALPRFVREKGV 1469 +KD+ NRKSN ++GTI +SNLC IE T P E VCNLA++ L F+RE G Sbjct: 399 FKDAINRKSNLSHVGTITNSNLC---IEVTIPCWEGDKAEQGVCNLAAVNLAAFIRENG- 454 Query: 1470 PIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPI 1649 +D+ L E + VT NL+ II+ YYP E RRSNMRHRPI Sbjct: 455 -------------------YDYRGLIEASGNVTENLDNIIDNGYYPTEATRRSNMRHRPI 495 Query: 1650 GIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPV 1829 GIGV GLAD F L M F SPEA ++ I +YY G + ++ GS Sbjct: 496 GIGVFGLADVFASLKMKFGSPEAIAMDEAIHAALYYGAMRRSIELAKEKGSHPSFPGSAA 555 Query: 1830 SKGIIQPDMW------------NVVPST-----RWNWPTLRETIAKVGVRNSLLVAPMPT 1958 SKG++QPD+W V +T R +W LR A GVRN L A MPT Sbjct: 556 SKGLLQPDLWVRCGDLSSSWEERVAQTTQGVLTRKSWWQLR-LAAMQGVRNGYLTALMPT 614 Query: 1959 ASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDG 2138 A++S G NECFEP+TSN+Y+RR LSGEF+V+NK+L+ DL E+ +WT A++ +++ G Sbjct: 615 ATSSNSTGKNECFEPFTSNLYTRRTLSGEFIVLNKYLIDDLKEIDLWTEAIQQQLLNAGG 674 Query: 2139 SIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVHMDQPNFAKLTSLH 2318 SIQ + +IP +++ YKT E+ QK L A R ++ QS SLN + +P +++ ++ Sbjct: 675 SIQHILDIPAEIRDRYKTSREMNQKILTKHAAARNPFVSQSMSLNYYFYEPELSQVLTVL 734 Query: 2319 FHAWSKGLKTGMYY 2360 W KGL TG YY Sbjct: 735 VLGWKKGLTTGSYY 748
>P26685:RIR1_ASFM2 Ribonucleoside-diphosphate reductase large chain - African swine| fever virus (isolate Malawi Lil 20/1) (ASFV) Length = 779 Score = 447 bits (1151), Expect = e-125 Identities = 279/734 (38%), Positives = 397/734 (54%), Gaps = 47/734 (6%) Frame = +3 Query: 300 HPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDIYEVIMKNAAR 479 H DY++LAAR++V LH++T SFS+ + R ++ +V+ K A Sbjct: 49 HYDYSTLAARLSVYLLHQSTASSFSKAVSLQAAQSCSR-------LSSHFVDVVYKYKAI 101 Query: 480 LDSEIIXXXXXXXXXXXXKTLERSYLLK-LGGVVVERPQHMLMRVSVGIHKD----DIDS 644 DS I +T++ SYLLK GV++ERPQ MRV++ IH ++ Sbjct: 102 FDSYIDYSRDYKLSLLGIETMKNSYLLKNKDGVIMERPQDAYMRVAIMIHGMGRVVNMKM 161 Query: 645 AIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKECAVISKSA 824 + TY L+S+ THASPT+FNAGT +PQLSSCFL+ + +D++E +YD +K +IS Sbjct: 162 ILLTYDLLSRHVITHASPTMFNAGTKKPQLSSCFLLNV-NDNLENLYDMVKTAGIISGGG 220 Query: 825 GGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWH 1004 GGIG+ + IRA S+I G+ SNGI + + N + Y +QGG R GA+AVYLE WH Sbjct: 221 GGIGLCLSGIRAKNSFISGSGLRSNGIQNYIVLQNASQCYANQGG-LRPGAYAVYLELWH 279 Query: 1005 ADIFEFLDLRKNHGK---EENRARDLFFALWVPDLFMQ----RVQNNED--WSPFCPNEA 1157 DIF FL + + G+ + A +L + LWVPDLFM+ ++ N D W F P++A Sbjct: 280 QDIFTFLQMPRLKGQMAEQRLNAPNLKYGLWVPDLFMEILEDQIHNRGDGTWYLFSPDQA 339 Query: 1158 PGLADCWGXXXXXXXXXXXXXXXXXX----------VIPAQTLWFDILKAQIETGTPYML 1307 P L + V A+ + + K ++ G PY+ Sbjct: 340 PNLHKVFDLERSQHENAHREFKKLYYQYVAEKRYTGVTTAKEIIKEWFKTVVQVGNPYIG 399 Query: 1308 YKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSP------EETAVCNLASIALPRFVREKGV 1469 +KD+ NRKSN ++GTI +SNLC IE T P E VCNLA++ L F+RE Sbjct: 400 FKDAINRKSNLSHVGTITNSNLC---IEITIPCWEGNEAEQGVCNLAAVNLAAFIRESS- 455 Query: 1470 PIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPI 1649 +D+ L E VT NL+ II+ YYP E RRSNMRHRPI Sbjct: 456 -------------------YDYRGLIEAAGNVTENLDNIIDNGYYPTEATRRSNMRHRPI 496 Query: 1650 GIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPV 1829 GIGV GLAD F L M F SPEA ++ I +YY G + ++ GS Sbjct: 497 GIGVFGLADVFASLKMKFGSPEAIAIDEAIHAALYYGAMRRSIELAKEKGSHPSFPGSAA 556 Query: 1830 SKGIIQPDMW----NVVPS-------------TRWNWPTLRETIAKVGVRNSLLVAPMPT 1958 SKG++QPD+W +++PS T W LR A GVRN L A MPT Sbjct: 557 SKGLLQPDLWVRCGDLIPSWENRVAQTTQGVLTPKKWWQLR-LAAIQGVRNGYLTALMPT 615 Query: 1959 ASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDG 2138 A++S G NECFEP+TSN+Y+RR LSGEF+++NK+L+ DL E+ +W+ ++ +++ G Sbjct: 616 ATSSNSTGKNECFEPFTSNLYTRRTLSGEFIILNKYLMDDLEEINLWSEDIQQQLLNAGG 675 Query: 2139 SIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVHMDQPNFAKLTSLH 2318 SIQ + +IP +++ YKT E+ QK L A R ++ QS SLN + +P +++ ++ Sbjct: 676 SIQHILDIPAEIRERYKTSREMNQKILTKHAAARNPFVSQSMSLNYYFYEPELSQVLTVL 735 Query: 2319 FHAWSKGLKTGMYY 2360 W KGL TG YY Sbjct: 736 VLGWKKGLTTGSYY 749
>O84834:RIR1_CHLTR Ribonucleoside-diphosphate reductase alpha subunit - Chlamydia| trachomatis Length = 1047 Score = 421 bits (1082), Expect = e-117 Identities = 280/844 (33%), Positives = 428/844 (50%), Gaps = 28/844 (3%) Frame = +3 Query: 96 VVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXXXX 275 V+ +DG T T+ ++ A L + + E D L+ A Y G+ S++ Sbjct: 239 VLSKDGSTYTMTHSQLLAHLAR-ACSRFPETTDAALLTDMAFANFYSGIKESEVVLACIM 297 Query: 276 XXXXXXXSHPDYASLAARIAVSNLHKNT--KKSFSETIKDMYLHYNERSGLLSPLIAE-D 446 PDYA +AA + + ++K K ++E ++ + + +R IAE D Sbjct: 298 AARANIEKEPDYAFVAAELLLDVVYKEALGKSKYAEDLEQAHRDHFKR------YIAEGD 351 Query: 447 IYEVI--MKNAARLDS---EIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRV 611 Y + +K+ LD+ + + L Y G +E PQ MRV Sbjct: 352 TYRLNAELKHLFDLDALADAMDLSRDLQFSYMGIQNLYDRYFNHHEGCRLETPQIFWMRV 411 Query: 612 SVGIHKDDIDS---AIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGI 782 ++G+ ++ D AI Y+L+S +T A+PTLFN+G QLSSC+L ++D+ + I Sbjct: 412 AMGLALNEQDKTSWAITFYNLLSTFRYTPATPTLFNSGMRHSQLSSCYLSTVQDNLVN-I 470 Query: 783 YDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGG 962 Y + + A++SK AGGIG IRATG+ I+GTNG S G++P ++V NDTA V+QGG Sbjct: 471 YKVIADNAMLSKWAGGIGNDWTAIRATGALIKGTNGRSQGVIPFIKVTNDTAVAVNQGG- 529 Query: 963 KRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPF 1142 KRKGA VYLE WH D +FL+LRKN G E RA D+ A W+PDLF +R+Q W+ F Sbjct: 530 KRKGAVCVYLEVWHLDYEDFLELRKNTGDERRRAHDVNIASWIPDLFFKRLQQKGTWTLF 589 Query: 1143 CPNEAPGLADCWGXXXXXXXXXXXXXXXXXXV-----IPAQTLWFDILKAQIETGTPYML 1307 P++ PGL D +G + + A+ LW +L ETG P+M Sbjct: 590 SPDDVPGLHDAYGEEFERLYEEYERKVDTGEIRLFKKVEAEDLWRKMLSMLFETGHPWMT 649 Query: 1308 YKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHP 1487 +KD N +S Q + G ++ SNLCTEI+ S ETAVCNL SI L + + G+ Sbjct: 650 FKDPSNIRSAQDHKGVVRCSNLCTEILLNCSETETAVCNLGSINLVQHIVGDGL------ 703 Query: 1488 SKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQG 1667 D +KL E S L+ +I++N+YP + A+ +N HR IG+GV G Sbjct: 704 --------------DEEKLSETISIAVRMLDNVIDINFYPTKEAKEANFAHRAIGLGVMG 749 Query: 1668 LADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQ 1847 D L + + S EA + E I Y+ G Y +Y+GS +G++ Sbjct: 750 FQDALYKLDISYASQEAVEFADYSSELISYYAIQASCLLAKERGTYSSYKGSKWDRGLLP 809 Query: 1848 PDMWNVVP------------STRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNE 1991 D ++ S+R +W +R + + G+R+ L+A PTA+ S I+G + Sbjct: 810 IDTIQLLANYRGEANLQMDTSSRKDWEPIRSLVKEHGMRHCQLMAIAPTATISNIIGVTQ 869 Query: 1992 CFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDD 2171 EP +++ + LSGEF + N +L+ L ++GIW + + + Y DGS+ ++E IPD Sbjct: 870 SIEPTYKHLFVKSNLSGEFTIPNVYLIEKLKKLGIWDADMLDDLKYFDGSLLEIERIPDH 929 Query: 2172 LKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTG 2351 LK I+ T +EI+ + +++ A R +ID QSLN+++ QP+ KL++++ AW KGLKT Sbjct: 930 LKHIFLTAFEIEPEWIIECASRRQKWIDMGQSLNLYLAQPDGKKLSNMYLTAWKKGLKT- 988 Query: 2352 MYYLRTRAAADAIKFTVDTGFLKVXXXXXXXXXXXXXKLAEEDDEAKMAQVVCSLNNREE 2531 YYLR+ +A K VD + + E +A VCSL E Sbjct: 989 TYYLRSSSATTVEKSFVDINKRGIQPRWMKNKSASAGIIVERAKKAP----VCSL--EEG 1042 Query: 2532 CLAC 2543 C AC Sbjct: 1043 CEAC 1046
>Q9PL93:RIR1_CHLMU Ribonucleoside-diphosphate reductase alpha subunit - Chlamydia| muridarum Length = 1047 Score = 421 bits (1081), Expect = e-116 Identities = 266/798 (33%), Positives = 411/798 (51%), Gaps = 28/798 (3%) Frame = +3 Query: 96 VVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXXXX 275 V+ +DG T + ++ ARL + + E D L+ + Y G+ S++ Sbjct: 239 VLSKDGSTYMITHSQLLARLAR-ACSRFPETTDAALLTDMAFSNFYSGIKESEVVLACIM 297 Query: 276 XXXXXXXSHPDYASLAARIAVSNLHKNT--KKSFSETIKDMYLHYNER------SGLLSP 431 PDYA +AA + + ++K + E ++ +Y + +R S L+P Sbjct: 298 AARANIEKEPDYAFVAAELLLDVVYKEALDRSRGDEDLEQVYRDHFKRYIMEGDSYRLNP 357 Query: 432 LIAEDIYEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMRV 611 + + NA L ++ + L Y G +E PQ MRV Sbjct: 358 ELKNLFDLDALANAMDLSRDL------QFSYMGIQNLYDRYFNHDDGRRLETPQIFWMRV 411 Query: 612 SVGIHKDDIDS---AIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGI 782 ++G+ + D AI Y+L+S +T A+PTLFN+G QLSSC+L ++DD + I Sbjct: 412 AMGLALKEQDKTYWAITFYNLLSTFRYTPATPTLFNSGMRHSQLSSCYLSTVQDDLVN-I 470 Query: 783 YDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGG 962 Y + + A++SK AGGIG IRATG+ I+GTNG S G++P ++V NDTA V+QGG Sbjct: 471 YKVISDNAMLSKWAGGIGNDWTAIRATGALIKGTNGKSQGVIPFIKVTNDTAVAVNQGG- 529 Query: 963 KRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPF 1142 KRKGA VYLE WH D +FL+LRKN G + RA D+ A W+PDLF +R+Q W+ F Sbjct: 530 KRKGAVCVYLEVWHLDYEDFLELRKNTGDDRRRAHDVNTASWIPDLFFKRLQQKGSWTLF 589 Query: 1143 CPNEAPGLADCWGXXXXXXXXXXXXXXXXXXV-----IPAQTLWFDILKAQIETGTPYML 1307 P++ PGL D +G + + A+ LW +L ETG P+M Sbjct: 590 SPDDVPGLHDAYGEEFERLYEEYERKVDSGEIRLYKKVEAEDLWRKMLSMLFETGHPWMT 649 Query: 1308 YKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHP 1487 +KD N +S Q + G ++ SNLCTEI+ S ETAVCNL S+ L + + + G+ Sbjct: 650 FKDPSNIRSAQDHTGVVRCSNLCTEILLNCSETETAVCNLGSVNLVQHILDDGL------ 703 Query: 1488 SKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQG 1667 D +KL E S L+ +I++N+YP + A+ +N HR IG+GV G Sbjct: 704 --------------DEEKLSETISIAVRMLDNVIDINFYPTKEAKEANFAHRAIGLGVMG 749 Query: 1668 LADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQ 1847 D L + + S EA + E I Y+ G Y +Y+GS +G++ Sbjct: 750 FQDALYKLDISYASQEAVEFADYSSELISYYAIQASCLLAKERGTYSSYKGSKWDRGLLP 809 Query: 1848 PDMWNVVP------------STRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNE 1991 D ++ S R +W +R I + G+RN L+A PTA+ S I+G + Sbjct: 810 IDTIQLLANYRGKDNLQMDTSVRKDWEPIRSLIREHGMRNCQLMAIAPTATISNIIGVTQ 869 Query: 1992 CFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDD 2171 EP +++ + LSGEF + N +L+ L ++GIW + + + Y DGS+ ++E +PD Sbjct: 870 SIEPTYKHLFVKSNLSGEFTIPNVYLIEKLKKLGIWDADMLDDLKYFDGSLLEIERVPDH 929 Query: 2172 LKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVHMDQPNFAKLTSLHFHAWSKGLKTG 2351 +K I+ T +EI+ + +++ A R +ID QSLN+++ QP+ KL++++ AW KGLKT Sbjct: 930 IKHIFLTAFEIEPEWILECASRRQKWIDMGQSLNLYLAQPDGKKLSNMYLTAWKKGLKT- 988 Query: 2352 MYYLRTRAAADAIKFTVD 2405 YYLR+ +A K VD Sbjct: 989 TYYLRSSSATTVEKSFVD 1006
>Q9Z6S5:RIR1_CHLPN Ribonucleoside-diphosphate reductase alpha subunit - Chlamydia| pneumoniae (Chlamydophila pneumoniae) Length = 1044 Score = 418 bits (1075), Expect = e-116 Identities = 267/804 (33%), Positives = 415/804 (51%), Gaps = 33/804 (4%) Frame = +3 Query: 93 YVV-KRDGRTETVHFDKITARLKKLSYGLSQ--EHCDPVLVAQKVCAGVYKGVTTSQLDX 263 YVV K DG T + + T K+ S+ + + D L+A +Y G+ ++ Sbjct: 235 YVVQKEDG---TTYLLRKTDLEKRFSWACKRFPKTTDSQLLADMAFMNLYSGIKEDEVTT 291 Query: 264 XXXXXXXXXXXSHPDYASLAARIAVSNLHKNT------KKSFSETIKDMYLHY--NERSG 419 PDYA +AA + S+L++ T + SE K + Y N Sbjct: 292 ACIMAARANIEREPDYAFIAAELLTSSLYEETLGCSSQDPNLSEIHKKHFKEYILNGEEY 351 Query: 420 LLSPLIAEDIYEVIMKNAARLDSEIIXXXXXXXXXXXX-KTLERSYLLKLGGVVVERPQH 596 L+P + + + + SE++ + L Y G +E Q Sbjct: 352 RLNPQLKDYDLDAL--------SEVLDLSRDQQFSYMGVQNLYDRYFNLHEGRRLETAQI 403 Query: 597 MLMRVSVGIHKDDIDS----AIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKD 764 MRVS+G+ ++ + AI Y+L+S +T A+PTLFN+G QLSSC+L +KD Sbjct: 404 FWMRVSMGLALNEGEQKNFWAITFYNLLSTFRYTPATPTLFNSGMRHSQLSSCYLSTVKD 463 Query: 765 DSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARY 944 D + IY + + A++SK AGGIG ++RATG+ I+GTNG S G++P ++V NDTA Sbjct: 464 D-LSHIYKVISDNALLSKWAGGIGNDWTDVRATGAVIKGTNGKSQGVIPFIKVANDTAIA 522 Query: 945 VDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNN 1124 V+QGG KRKGA VYLE WH D +FL+LRKN G E R D+ A W+PDLF +R++ Sbjct: 523 VNQGG-KRKGAMCVYLENWHLDYEDFLELRKNTGDERRRTHDINTASWIPDLFFKRLEKK 581 Query: 1125 EDWSPFCPNEAPGLADCWGXXXXXXXXXXXXXXXXXXV-----IPAQTLWFDILKAQIET 1289 W+ F P++ PGL + +G + + A+ LW +L ET Sbjct: 582 GMWTLFSPDDVPGLHEAYGLEFEKLYEEYERKVESGEIRLYKKVEAEVLWRKMLSMLYET 641 Query: 1290 GTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGV 1469 G P++ +KD N +SNQ ++G ++ SNLCTEI+ S ETAVCNL SI L +R Sbjct: 642 GHPWITFKDPSNIRSNQDHVGVVRCSNLCTEILLNCSESETAVCNLGSINLVEHIR---- 697 Query: 1470 PIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPI 1649 N D +KL E S L+ +I++N+YP A+++N+ HR + Sbjct: 698 ----------------NDKLDEEKLKETISIAIRILDNVIDLNFYPTPEAKQANLTHRAV 741 Query: 1650 GIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPV 1829 G+GV G D L + + S EA + + + E I Y+ G Y +Y GS Sbjct: 742 GLGVMGFQDVLYELNISYASQEAVEFSDECSEIIAYYAILASSLLAKERGTYASYSGSKW 801 Query: 1830 SKGIIQPDMWNVVPSTRW------------NWPTLRETIAKVGVRNSLLVAPMPTASTSQ 1973 +G + D ++ TR +W +R+TI K G+RNS ++A PTA+ S Sbjct: 802 DRGYLPLDTIELLKETRGEHNVLVDTSSKKDWTPVRDTIQKYGMRNSQVMAIAPTATISN 861 Query: 1974 ILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKM 2153 I+G + EP +++ + LSGEF + N +L+ L E+G+W + + + Y DGS+ ++ Sbjct: 862 IIGVTQSIEPMYKHLFVKSNLSGEFTIPNTYLIKKLKELGLWDAEMLDDLKYFDGSLLEI 921 Query: 2154 EEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVHMDQPNFAKLTSLHFHAWS 2333 E IP+ LK ++ T +EI+ + +++ R +ID SLN+++ +P+ KL++++ AW Sbjct: 922 ERIPNHLKKLFLTAFEIEPEWIIECTSRRQKWIDMGVSLNLYLAEPDGKKLSNMYLTAWK 981 Query: 2334 KGLKTGMYYLRTRAAADAIKFTVD 2405 KGLKT YYLR++AA K +D Sbjct: 982 KGLKT-TYYLRSQAATSVEKSFID 1004
>O66503:RIR1_AQUAE Ribonucleoside-diphosphate reductase alpha subunit - Aquifex aeolicus| Length = 801 Score = 305 bits (780), Expect = 9e-82 Identities = 244/839 (29%), Positives = 391/839 (46%), Gaps = 74/839 (8%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXX 269 MYV+KR GR E + +KI +K GL+ DP+ + G+TT ++ Sbjct: 3 MYVIKRSGRKEKLDINKIRIAIKFACEGLN---VDPLELEADAQIQFRDGITTKEIQQLL 59 Query: 270 XXXXXXXXXSH-PDYASLAARIAVSNLHKNTKKSFSETIKD---MYLHYNERS--GLLSP 431 + PD+ AAR+ + +L+K+ +++D Y YN ++ + Sbjct: 60 IKTAAEKVSAERPDWTYTAARLLLYDLYKDVAHLRGYSLRDDLGKYKPYNRKNFYSFVKE 119 Query: 432 LIAEDIY-EVIMKNAA-----RLDSEIIXXXXXXXXXXXXKTLERSYLLK-LGGVVVERP 590 + + IY E +++N + +L + I K L YL++ G V+E P Sbjct: 120 YVEKGIYGEYLLENYSEEDFNKLANYIKPERDLYFTYTGIKILYDRYLVRDEEGRVIELP 179 Query: 591 QHMLMRVSVGIH-----KDDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLIC 755 Q M M +++ + ++ + A + Y ++S+ T A+PTL NA P QLSSCF++ Sbjct: 180 QEMYMLIAMTLAVPEKPEERLKWAKKFYDVLSEHKVTVATPTLMNARRPFTQLSSCFVLT 239 Query: 756 MKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDT 935 + DD + I+D +K+ +ISK AGG+GV + IRATG+ IR G S+G++P++++ NDT Sbjct: 240 VDDDLFD-IFDNVKKAGMISKFAGGLGVYLGKIRATGAPIRKFKGASSGVIPVVKLINDT 298 Query: 936 ARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRV 1115 YVDQ G RKG+ ++ L+ WH DI +FL+++ N G E +A D+ A+ +PDLFM+R+ Sbjct: 299 MTYVDQ-LGMRKGSASITLDIWHKDILDFLEVKTNVGDERKKAHDIHPAVSIPDLFMKRL 357 Query: 1116 QNNEDWSPFCPN---------------------------------------EAPGLADCW 1178 +N EDW+ P E GL D + Sbjct: 358 KNREDWTLIDPYWARQYITRKIYDGKYKEVKPLPGSHYYVGIKEDGTQDILEPKGLEDFY 417 Query: 1179 G--XXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLG 1352 G + + LW +L ETG PY+ ++D NRK+ ++ G Sbjct: 418 GEEFEKWYLELEENLPSYAKKKVNSFELWKRLLTVAFETGEPYIFFRDEANRKNPNKHTG 477 Query: 1353 TIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKG-VPIESHPSKLAGSN-GSKN-- 1520 + SSNLC EI++ SP + P E G + + L N GS N Sbjct: 478 MVYSSNLCHEIVQTMSPSKH--------EKPVLDPETGEITYKKEAGDLPVCNLGSVNLG 529 Query: 1521 RYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMP 1700 + +++ EV + L+ +IEMN+Y + A +N R+R IGIGV + G+ Sbjct: 530 KVHTEEEIKEVLPLLVRMLDNVIEMNFYAIPEAEYTNKRYRAIGIGVSNYHYCLVKNGIK 589 Query: 1701 FDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGII-QPDMWNVVPST 1877 ++S E + +FE I ++ G Y+ ++GS SKGI+ + + ++ Sbjct: 590 WESEEHLKFADKLFELIAFYALKGSLELAKERGRYKLFDGSNWSKGILFGRSVEEIEENS 649 Query: 1878 RWN-----WPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSG 2042 R N W L E I K G+RN+ L+A MPT STS ILG +P + Y +SG Sbjct: 650 RQNGNNLPWRELAEEIKKYGIRNAYLLALMPTGSTSLILGATPSIDPIFARFYKEENMSG 709 Query: 2043 EFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAI---YKTVWEIKQK 2213 + ++P ++ YKT + I + Sbjct: 710 -----------------------------------ILPQVPPEVDRFYWHYKTAYTIDHE 734 Query: 2214 TLVDMAVDRGCYIDQSQSLNVHMDQPNF--AKLTSLHFHAWSKGLKTGMYYLRTRAAAD 2384 + A R +IDQ+QSLN+ +D N +L+ L+ AW GLKT +YYLR+R+A D Sbjct: 735 WTIRAAAVRQKWIDQAQSLNLFVDPQNIDGPRLSRLYELAWELGLKT-IYYLRSRSAMD 792
>Q9ZLF9:RIR1_HELPJ Ribonucleoside-diphosphate reductase alpha subunit - Helicobacter| pylori J99 (Campylobacter pylori J99) Length = 788 Score = 287 bits (734), Expect = 2e-76 Identities = 248/822 (30%), Positives = 375/822 (45%), Gaps = 52/822 (6%) Frame = +3 Query: 96 VVKRDGRTETVHFDKITARLKKLS---YGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXX 266 VVKR+GR E + KI K + G+SQ + Q +TT ++ Sbjct: 4 VVKRNGRIEPLDITKIQKYTKDATDNLEGVSQSELEVDARLQ-----FRDKITTEEIQQT 58 Query: 267 XXXXXXXXXX-SHPDYASLAARIAVSNL-HKNTKKSFSETIKDMYLHYNERSGLLSPLIA 440 P+++ +A+R+ + +L HK + + +K+ + + E+ +L Sbjct: 59 LIKTAVDKIDIDTPNWSFVASRLFLYDLYHKVSGFTGYRHLKEYFENAEEKGRILKGFKE 118 Query: 441 EDIYEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLK-LGGVVVERPQHMLMRVSV 617 + E L+S+I KTL YLLK +E PQHM M +++ Sbjct: 119 KFDLEF-------LNSQIKPERDFQFNYLGIKTLYDRYLLKDANNHPIELPQHMFMSIAM 171 Query: 618 GIHKDDIDS---AIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYD 788 + +++ + A+ Y ++S+ A+PTL NA T + QLSSC+ I D+IEGI+D Sbjct: 172 FLAQNEQELNKIALEFYEVLSKFEAMCATPTLANARTTKHQLSSCY-IGSTPDNIEGIFD 230 Query: 789 TLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKR 968 + KE A++SK GGIG +R+ GSYI G S G +P L++ ND A VDQ G R Sbjct: 231 SYKEMALLSKYGGGIGWDFSLVRSIGSYIDGHKNASAGTIPFLKIANDVAIAVDQLG-TR 289 Query: 969 KGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCP 1148 KGA AVYLE WH D+ EF+DLRKN G E RA DLF ALWV DLFM+RV + W+ F P Sbjct: 290 KGAIAVYLEIWHIDVMEFIDLRKNSGDERRRAHDLFPALWVCDLFMKRVLEDAMWTLFDP 349 Query: 1149 NEAPGLADCWG-XXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCN 1325 E L + +G I A+ LW IL E G P++ +KD+ N Sbjct: 350 YECKDLTELYGQDFEKRYLEYEKDPKIIKEYINAKDLWKKILMNYFEAGLPFLAFKDNAN 409 Query: 1326 RKSNQQNLGTIKSSNLCTEIIEFTSPEETAV-CNLASIALPRFVREKGVPIESHPSKLAG 1502 R + + G I+SSNLCTEI + T+P + A+ F ++ V +S+ +K A Sbjct: 410 RCNPNAHAGIIRSSNLCTEIFQNTAPNHYYMQIEYTDGAIEFFEEKELVTTDSNITKCAN 469 Query: 1503 SNGSKN-----RYFDFDKLGE-----VTSTVTFNLNKI--------------------IE 1592 S + + + K+ + V + + NL+KI I+ Sbjct: 470 KLTSTDILKGKKIYIATKVAKDGQTAVCNLASINLSKINTEEDIKRVVPIMVRLLDNVID 529 Query: 1593 MNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXX 1772 +N+YP + +N+++R IG+GV G A + + S E + + E I YH Sbjct: 530 LNFYPNRKVKATNLQNRAIGLGVMGEAQMLAEHQIAWGSKEHLEKIDALMEQISYHAIDT 589 Query: 1773 XXXXXXXXGPYETYEGSPVSKGIIQPDMWN-----VVPSTRWN----WPTLRETIAKVGV 1925 G Y+ +E S SKGI D N + +N W LRE + G+ Sbjct: 590 SANLAKEKGVYKDFENSEWSKGIFPIDKANNEALKLTEKGLFNHACDWQGLREKVKANGM 649 Query: 1926 RNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTP 2105 RN L+A PT+S S ++G + EP + LSG VV +L + W Sbjct: 650 RNGYLMAIAPTSSISILVGTTQTIEPIYKKKWFEENLSGLIPVVVPNL-----NVETWN- 703 Query: 2106 ALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVHMD 2285 Y + ++I K L+ A R +IDQ QS+NV + Sbjct: 704 -------------------------FYTSAYDIDAKDLIKAAAVRQKWIDQGQSINVFLR 738 Query: 2286 QPNFA--KLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVD 2405 N + L ++ AW GLK+ YYLR+ + + K +D Sbjct: 739 IENASGKTLHEIYTLAWKLGLKS-TYYLRSESPSIDEKSVLD 779
>P55982:RIR1_HELPY Ribonucleoside-diphosphate reductase alpha subunit - Helicobacter| pylori (Campylobacter pylori) Length = 788 Score = 285 bits (729), Expect = 7e-76 Identities = 250/824 (30%), Positives = 370/824 (44%), Gaps = 54/824 (6%) Frame = +3 Query: 96 VVKRDGRTETVHFDKITARLKKLS---YGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXX 266 VVKR+GR E + KI K + G+SQ + Q +TT ++ Sbjct: 4 VVKRNGRIEPLDITKIQKYTKDATDNLEGVSQSELEVDARLQ-----FRDKITTEEIQQT 58 Query: 267 XXXXXXXXXX-SHPDYASLAARIAVSNL-HKNTKKSFSETIKDMYLHYNERSGLLSPLIA 440 P+++ +A+R+ + +L HK + + +K+ + + E+ +L Sbjct: 59 LIKTAVDKIDIDTPNWSFVASRLFLYDLYHKVSGFTGYRHLKEYFENAEEKGRILKGFKE 118 Query: 441 EDIYEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLLK-LGGVVVERPQHMLMRVSV 617 + E L+S+I KTL YLLK +E PQHM M +++ Sbjct: 119 KFDLEF-------LNSQIKPERDFQFNYLGIKTLYDRYLLKDANNNPIELPQHMFMSIAM 171 Query: 618 GIHKDDIDS---AIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYD 788 + +++ + A+ Y ++S+ A+PTL NA T + QLSSC+ I D+IEGI+D Sbjct: 172 FLAQNEQEPNKIALEFYEVLSKFEAMCATPTLANARTTKHQLSSCY-IGSTPDNIEGIFD 230 Query: 789 TLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKR 968 + KE A++SK GGIG +R+ GSYI G S G +P L++ ND A VDQ G R Sbjct: 231 SYKEMALLSKYGGGIGWDFSLVRSIGSYIDGHKNASAGTIPFLKIANDVAIAVDQLG-TR 289 Query: 969 KGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCP 1148 KGA AVYLE WH D+ EF+DLRKN G E RA DLF ALWV DLF++RV + W+ F P Sbjct: 290 KGAIAVYLEIWHIDVMEFIDLRKNSGDERRRAHDLFPALWVCDLFLKRVLEDAMWTLFDP 349 Query: 1149 NEAPGLADCWG-XXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCN 1325 E L + +G I A+ LW IL E G P++ +KD+ N Sbjct: 350 YECKDLTELYGQDFEKRYLEYEKDPKIIKEYINAKDLWKKILMNYFEAGLPFLAFKDNAN 409 Query: 1326 RKSNQQNLGTIKSSNLCTEIIEFTSPEE---------------------TAVCNLASIA- 1439 R + + G I+SSNLCTEI + T+P T N+ A Sbjct: 410 RCNPNAHAGIIRSSNLCTEIFQNTAPNHYYMQIEYTDGTIEFFEEKELVTTDSNITKCAN 469 Query: 1440 -LPRFVREKGVPI----------ESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKI 1586 L KG PI ++ LA N SK + + V + L+ + Sbjct: 470 KLTSTDILKGKPIYIATKVAKDGQTAVCNLASINLSKIN--TEEDIKRVVPIMVRLLDNV 527 Query: 1587 IEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXX 1766 I++N+YP + +N+++R IG+GV G A + + S E + + E I YH Sbjct: 528 IDLNFYPNRKVKATNLQNRAIGLGVMGEAQMLAEHQIAWGSKEHLEKIDALMEQISYHAI 587 Query: 1767 XXXXXXXXXXGPYETYEGSPVSKGIIQPDMWN-----VVPSTRWN----WPTLRETIAKV 1919 G Y+ +E S SKGI D N + +N W LRE + Sbjct: 588 DTSANLAKEKGVYKDFENSEWSKGIFPIDKANNEALKLTEKGLFNHACDWQGLREKVKAN 647 Query: 1920 GVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIW 2099 G+RN L+A PT+S S ++G + EP + LSG VV +L + W Sbjct: 648 GMRNGYLMAIAPTSSISILVGTTQTIEPIYKKKWFEENLSGLIPVVVPNL-----NVETW 702 Query: 2100 TPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVH 2279 Y + ++I K L+ A R +IDQ QSLNV Sbjct: 703 N--------------------------FYTSAYDIDAKDLIKAAAVRQKWIDQGQSLNVF 736 Query: 2280 MDQPNFA--KLTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVD 2405 + N + L ++ AW GLK+ YYLR+ + + K +D Sbjct: 737 LRIENASGKTLHDIYTLAWKLGLKS-TYYLRSESPSIDEKSVLD 779
>P50642:RIR1_EHV4 Ribonucleoside-diphosphate reductase large chain - Equine herpesvirus| 4 (strain 1942) (EHV-4) (Equine rhinopneumonitis virus) Length = 789 Score = 256 bits (653), Expect = 5e-67 Identities = 178/587 (30%), Positives = 290/587 (49%), Gaps = 22/587 (3%) Frame = +3 Query: 690 ASPTLFNAGTPRPQLSSCFLICMK-DDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATG 866 A+P + G ++SC+L+ + D I ++E I + GGIG+S+ Sbjct: 206 ATPIMLFGGRDCGSMASCYLLNPRVTDMNSAIPALMEEVGPILCNRGGIGLSLQRFNTPP 265 Query: 867 SYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHG 1046 T G S G++ +L++ + ++ G + G VY EPWHADI L++R Sbjct: 266 -----TEGCSRGVMALLKLLDSMTMAINSDGERPTGV-CVYFEPWHADIRAILNMRGMLA 319 Query: 1047 KEEN-RARDLFFALWVPDLFMQRVQNNED------WSPFCPNEAPGLADCWGXXXXXXXX 1205 ++E R ++F +W PDLF R Q D W+ F + A L +G Sbjct: 320 RDETVRCDNIFACMWTPDLFFDRYQRYVDGESGIMWTLF-DDTASHLCHMYGNDFTREYE 378 Query: 1206 XXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSN--QQNLGTIKSSNLCT 1379 IP Q + F I+++ + TG+P++++KD+CNR + + G I SNLCT Sbjct: 379 RLERCGFGIDAIPIQDMAFIIVRSAVMTGSPFLMFKDACNRHYHFDMRQRGAIMGSNLCT 438 Query: 1380 EIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTS 1559 EII+ + VCNLASI LP+ + +P P +AG YFDF LG + Sbjct: 439 EIIQHADETQNGVCNLASINLPKCL---ALP----PPNIAGVP-----YFDFAALGRAAA 486 Query: 1560 TVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDI 1739 T T +N ++ + YP +++ +R +G+G+QGL TF++L + SPEA QLN+ I Sbjct: 487 TATIFVNAMMCASTYPTVKSQKGVEENRSLGLGIQGLHTTFLMLDLDMASPEAHQLNKQI 546 Query: 1740 FETIYYH-XXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMW-NVVPSTRWNWPTLRETIA 1913 E + + P++ +E S S+G + D + NV + R W LR I Sbjct: 547 AERLLLNSMKASATLCKLGMQPFKGFEDSKYSRGELPFDAYPNVTLTNRNAWRRLRTDIK 606 Query: 1914 KVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMG 2093 + G+ NS VA MPT S+SQ+ ++E F P +N++S+ +GE + N L+ + + Sbjct: 607 QYGLYNSQFVAYMPTVSSSQVTESSEGFSPVYTNLFSKVTATGEVLRPNVLLMRTIRSIF 666 Query: 2094 IWTPALKNKIIYEDGSIQKMEEIPDDLK-----AIYKTVWEIKQKTLVDMAVDRGCYIDQ 2258 A + + + + DL + +KT +E Q L++M DR ++DQ Sbjct: 667 PQECARLQALSTLEAAKWSVVGAFGDLPVGHPLSKFKTAFEYDQTMLINMCADRAAFVDQ 726 Query: 2259 SQSLNVHMDQPNFAKL-----TSLHFHAWSKGLKTGMYYLRTRAAAD 2384 SQS+++ + +P KL +L HA+ +GLKTGMYY + + A + Sbjct: 727 SQSMSLFITEPADGKLPASRIMNLLVHAYKRGLKTGMYYCKIKKATN 773
>P50646:RIR1_BHV1C Ribonucleoside-diphosphate reductase large chain - Bovine herpesvirus| 1.1 (strain Cooper) (BoHV-1) (Infectious bovine rhinotracheitis virus) Length = 787 Score = 253 bits (645), Expect = 4e-66 Identities = 186/596 (31%), Positives = 289/596 (48%), Gaps = 26/596 (4%) Frame = +3 Query: 690 ASPTLFNAGTPRPQLSSCFLICMK-DDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATG 866 A+P + AG R L+SC+L+ + S E + E A I + GGIG+S + Sbjct: 208 ATPIMLFAGRARGSLASCYLLNPQVSSSTEAVEAITTEVARILLNRGGIGISFQSFDRAV 267 Query: 867 SYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHG 1046 S GI+ L++ + A ++ + G VYLEPWH D+ L++R Sbjct: 268 S-----RDCKRGIMGALKLLDSMAMAINSDSERPTG-ICVYLEPWHCDVRAVLNMRGLLA 321 Query: 1047 KEEN-RARDLFFALWVPDLFMQR----VQNNED--WSPFCPNEAPGLADCWGXXXXXXXX 1205 ++E+ R +LF LWVPDL R ++ E W+ F + A L+ G Sbjct: 322 RDESTRCDNLFSCLWVPDLLFDRYLAHLEGREGVVWTLF-DDRASHLSRLHGPAFTAEYE 380 Query: 1206 XXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLG-TIKSSNLCTE 1382 +P Q L F I+++ + TG+P++++KD+CNR + G + SNLCTE Sbjct: 381 RLEREGLGVETVPVQDLAFLIVRSIVMTGSPFVMFKDACNRHYHMDTAGDALTGSNLCTE 440 Query: 1383 IIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTST 1562 I++ SP+ VCNLAS+ LPR VRE G G+ FDF L +T Sbjct: 441 IVQRASPDAHGVCNLASVNLPRCVRE-------------GEGGALA--FDFAALSTAAAT 485 Query: 1563 VTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIF 1742 +N ++ YP E A R RHR +GIG QGL + LGM SP A++LN +I Sbjct: 486 AAIFVNAMMLGGQYPTEKAARGVARHRSLGIGFQGLHTLLLELGMDMLSPAARRLNVEIA 545 Query: 1743 ETIYYH-XXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMW-NVVPSTRWNWPTLRETIAK 1916 E + P+E + S ++G++ D + VV S W LRE +A+ Sbjct: 546 ERLLLAVMATSATLCEYGCAPFEDFARSKFARGLMPFDGYEGVVLSLPRAWARLREKVAR 605 Query: 1917 VGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFV--------VVNKHLL 2072 G+ N+ VA MPT S+SQ+ +E F P +N++S+ +SGE + + KH Sbjct: 606 HGLYNAQFVALMPTVSSSQVTEGSEGFSPVFTNMFSKVTMSGELLRPNLPLMRALRKHFT 665 Query: 2073 HDLTEMGIWTPALKNKIIYEDGSIQKM--EEIPDDLKAIYKTVWEIKQKTLVDMAVDRGC 2246 + + +G + E S+ + P A +KT +E Q+ L+D+ DR Sbjct: 666 REASRLG-----AVRALDREQWSVAAALGDLAPGHPLAKFKTAFEYDQERLIDLCADRAP 720 Query: 2247 YIDQSQSLNVHMDQPNFAK-----LTSLHFHAWSKGLKTGMYYLRTRAAADAIKFT 2399 ++DQSQS+++ + +P K + +L +A+ KGLKTG+YY + R A + FT Sbjct: 721 FVDQSQSMSLFVTEPMDGKVPASQIMNLLVYAYKKGLKTGLYYCKIRKATNNGVFT 776
>P28846:RIR1_EHV1B Ribonucleoside-diphosphate reductase large chain - Equine herpesvirus| 1 (strain Ab4p) (EHV-1) (Equine abortion virus) Length = 790 Score = 252 bits (644), Expect = 5e-66 Identities = 177/587 (30%), Positives = 289/587 (49%), Gaps = 22/587 (3%) Frame = +3 Query: 690 ASPTLFNAGTPRPQLSSCFLICMK-DDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATG 866 A+P + G L+SC+L+ + D + ++E I + GGIG+S+ Sbjct: 207 ATPIMLFGGRDCGSLASCYLLNPRVTDMNSAMLALMEEAGPILCNRGGIGLSLQRFNTPP 266 Query: 867 SYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHG 1046 G S G++ +L++ + ++ G + G VY EPWHADI L++R Sbjct: 267 K-----EGCSRGVMALLKLIDSMTMAINSDGERPTGV-CVYFEPWHADIRAILNMRGMLA 320 Query: 1047 KEEN-RARDLFFALWVPDLFMQRVQNNED------WSPFCPNEAPGLADCWGXXXXXXXX 1205 ++E R ++F +W PDLF R Q D W+ F + A L +G Sbjct: 321 RDETVRCDNIFACMWTPDLFFDRYQRYLDGESGVMWTLF-DDTASHLCHMYGKEFEEEYE 379 Query: 1206 XXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSN--QQNLGTIKSSNLCT 1379 IP Q + F I+++ + TG+P++++KD+CN+ + + G I SNLCT Sbjct: 380 RLEQCGFGVDSIPIQDMAFIIVRSAVMTGSPFLMFKDACNKHYHFDLRRKGAIMGSNLCT 439 Query: 1380 EIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTS 1559 EII+ + VCNLASI LP+ + +P P AG YFDF LG + Sbjct: 440 EIIQHADETQNGVCNLASINLPKCL---AIP----PPHTAGVP-----YFDFAALGRAAA 487 Query: 1560 TVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDI 1739 T T +N ++ YP ++R +R +G+G+QGL F++L + SPEA+QLN+ I Sbjct: 488 TATIFVNSMMRAGTYPTVKSQRGVDENRSLGLGIQGLHTAFLMLDLDMASPEARQLNKQI 547 Query: 1740 FETIYYH-XXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMW-NVVPSTRWNWPTLRETIA 1913 E + + P++ +E S S G + D + V + R W LR I Sbjct: 548 AERLLLNSMKASATLCRLGMKPFKGFEDSKYSLGELPFDSYPGVTLANRNAWRRLRTEIK 607 Query: 1914 KVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEM- 2090 + G+ NS VA MPT S+SQ+ ++E F P +N++S+ +GE + N L+ + + Sbjct: 608 QHGLYNSQFVAYMPTVSSSQVTESSEGFSPVYTNLFSKVTATGEVLRPNLLLMRTIRSIF 667 Query: 2091 ---GIWTPALKNKIIYEDGSIQKMEEIP-DDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQ 2258 AL + + + ++P + +KT +E Q+TL+DM DR ++DQ Sbjct: 668 PRECARLQALSTLEMAQWSVVGAFGDLPVGHPLSKFKTAFEYDQRTLIDMCADRAPFVDQ 727 Query: 2259 SQSLNVHMDQP-----NFAKLTSLHFHAWSKGLKTGMYYLRTRAAAD 2384 SQS+++ + +P +K+ SL HA+ +GLKTGMYY + + A + Sbjct: 728 SQSMSLFITEPADGKLPASKIMSLLVHAYKRGLKTGMYYCKIKKATN 774
>P50643:RIR1_PRVKA Ribonucleoside-diphosphate reductase large chain - Pseudorabies virus| (strain Kaplan) (PRV) Length = 835 Score = 237 bits (605), Expect = 2e-61 Identities = 177/594 (29%), Positives = 283/594 (47%), Gaps = 24/594 (4%) Frame = +3 Query: 690 ASPTLFNAGTPRPQLSSCFLIC----MKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIR 857 A+P + AG R L+SC+L+ ++++ I D E A I GG+G+S+ + Sbjct: 261 ATPLMLFAGRARGSLASCYLLNPLPRTTEEAVRAITD---EVAPILLRRGGVGLSLQSFN 317 Query: 858 ATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRK 1037 T S + GI+ +L+ + ++ + G VY+EPWHAD+ L++R Sbjct: 318 RTPS-----GDCTRGIMAVLKALDSMTAAINSDSERPTGV-CVYVEPWHADVRAVLNMRG 371 Query: 1038 NHGKEEN-RARDLFFALWVPDLFMQRVQNNED------WSPFCPNEAPGLADCWGXXXXX 1196 +E+ R ++F LW PDLF QR Q + D W+ F + A LA G Sbjct: 372 MLAADESLRCDNIFSCLWTPDLFFQRYQRHLDGERAVKWTLF-DDRASHLASLHGPDFAR 430 Query: 1197 XXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGT-IKSSNL 1373 +P Q + F I+++ + TG+P+++ KD+CNR + G + +SNL Sbjct: 431 EYERLERLGLGVESLPIQDMAFLIVRSAVMTGSPFLMMKDACNRHFHTDTRGAALATSNL 490 Query: 1374 CTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEV 1553 CTEI++ +P E VCNLAS+ LP + LAG FDF L Sbjct: 491 CTEIVQRATPGENGVCNLASVNLP--------------ACLAGGA------FDFAALRRA 530 Query: 1554 TSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNR 1733 +N ++ + YP + R R +GIG+QGL T + L M P A++LN Sbjct: 531 ARVAAVFVNAMMRIGNYPTGASVEGVRRSRSLGIGLQGLHTTVLALDMDMADPAARRLNA 590 Query: 1734 DIFETIYYHXXXXXXXXXXXX-GPYETYEGSPVSKGIIQPDMWNVVPSTR-WNWPTLRET 1907 I E + Y P++ +E S ++G++ D + V W LR Sbjct: 591 AIAEELLYGVMDASVELCERGLRPFDGFEHSRYARGVMPFDAYERVSLREPMRWDALRVR 650 Query: 1908 IAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTE 2087 IA+ GV N+ VA MPT S+SQ+ ++E F P +N++S+ +SGE + N L+ L Sbjct: 651 IAEHGVYNAQFVALMPTVSSSQVTESSEGFSPTFTNMFSKVTISGELLRPNLPLMETLRR 710 Query: 2088 MGIWTPALKNKIIYEDGSIQKMEEIPDDLK-----AIYKTVWEIKQKTLVDMAVDRGCYI 2252 + A ++ + + + + +L A +KT +E Q+ L+DM DR ++ Sbjct: 711 LFPRECARRDAVARLERAQWSVAAAFGELPAGHPLAKFKTAFEYDQELLIDMCADRAPFV 770 Query: 2253 DQSQSLNVHMDQPNFAKL-----TSLHFHAWSKGLKTGMYYLRTRAAADAIKFT 2399 D SQS+++ + +P KL L A++ GLKTGMYY + R A + FT Sbjct: 771 DHSQSMSLFLTEPADGKLHASRVMGLLMRAYNLGLKTGMYYCKIRKATNNGVFT 824
>O83972:RIR1_TREPA Ribonucleoside-diphosphate reductase alpha subunit - Treponema| pallidum Length = 845 Score = 235 bits (600), Expect = 7e-61 Identities = 189/629 (30%), Positives = 297/629 (47%), Gaps = 19/629 (3%) Frame = +3 Query: 546 RSYLLKLGG-VVVERPQHMLMRVSVGIHKDDIDSAI----RTYHLMSQRWFTHASPTLFN 710 R Y+++ V +E PQ M + +++ + ++ + R Y ++S+ T A+PTL N Sbjct: 249 RRYVIRTRAHVPLETPQEMFLGIALHLAMNETQDRMQWVKRFYTVLSKLQVTVATPTLSN 308 Query: 711 AGTPRPQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNG 890 A P QLSSCF+ + D S++GIY ++ + +SK GG+G+ +RA G+ IRG G Sbjct: 309 ARKPFHQLSSCFVDTVPD-SLDGIYRSIDNFSQVSKFGGGMGLYFGKVRAVGAPIRGFQG 367 Query: 891 TSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARD 1070 + GI+ +++ NDTA VDQ G R+G+ AVYL+ WH DI EFL LR N+G + +A D Sbjct: 368 AAGGILRWIKLANDTAVAVDQLG-VRQGSVAVYLDVWHKDIPEFLQLRTNNGDDRMKAHD 426 Query: 1071 LFFALWVPDLFMQRVQNN--EDWSPFCPNE-----APGLADCWG-XXXXXXXXXXXXXXX 1226 +F A+ PDLF + V++N W CP+E L D + Sbjct: 427 VFPAVCYPDLFWKTVRDNLGASWYLMCPHEILTVKGYALEDFYAEEWEKRYWDCVKDARI 486 Query: 1227 XXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPE 1406 IP + L +LK+ +ETGTP+ Y+D NR + + G I SNLCTEI + Sbjct: 487 SKRTIPIKELVRLVLKSVVETGTPFAFYRDHANRANPNGHRGIIYCSNLCTEI-----AQ 541 Query: 1407 ETAVCNLASIALPRFVREKGVPIESHPS-----KLAGSNGSKNRYFDFDKLGEVTSTVTF 1571 + NL S+ + +K V + P LA S D +L EV Sbjct: 542 NMSAINLVSVKITEVDGQKVVVQTTRPGDFVVCNLASLVLSNIDLSDDKELREVVRVAVR 601 Query: 1572 NLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETI 1751 L+ +I++ YYPV A+ +N +R IG+GV G G+ ++S E IFE I Sbjct: 602 ALDNVIDLTYYPVPYAQVTNAYYRAIGLGVSGYHHVLAQQGIDWESDEHLAFADRIFERI 661 Query: 1752 YYHXXXXXXXXXXXXGPYETYEGSPVSKGIIQPDMWNVVPSTRWNWPTLRETIAKVGVRN 1931 G Y + GS G V +W L+ +A G+RN Sbjct: 662 NRAAIEASMTIAREKGAYGCFTGSDWCTGAYFRKRGYVSE----DWQRLQREVATHGMRN 717 Query: 1932 SLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPAL 2111 L+A PT+STS I G +P ++ F+ K +L M P+L Sbjct: 718 GYLLAVAPTSSTSIIAGTTAGVDP---------IMKQYFLEEKKGML-----MPRVAPSL 763 Query: 2112 KNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVHMDQP 2291 K +YK+ ++Q+ + A R +IDQ+QS+N+++ Sbjct: 764 SQKTC-----------------PLYKSAHAVEQRWSIRAAGLRQRHIDQAQSVNLYITTD 806 Query: 2292 -NFAKLTSLHFHAWSKGLKTGMYYLRTRA 2375 ++ L+ +AW G+K+ +YY+R+++ Sbjct: 807 FTLKQVLDLYVYAWEVGMKS-LYYVRSQS 834
>P74240:RIR1_SYNY3 Ribonucleoside-diphosphate reductase alpha subunit - Synechocystis| sp. (strain PCC 6803) Length = 767 Score = 221 bits (563), Expect = 1e-56 Identities = 187/672 (27%), Positives = 296/672 (44%), Gaps = 27/672 (4%) Frame = +3 Query: 87 KMYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQL-DX 263 ++ V++RDG + ++ KI A + GL + + + + + +G++T ++ D Sbjct: 30 RIQVIRRDGSSTPLNIGKIRAVVDWACLGLE---VNSIALEAGLTTRLREGISTREIQDN 86 Query: 264 XXXXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAE 443 + PD+ +A R+ V +L K+T ++ Y Y + + + Sbjct: 87 LISCALEMCSPNEPDWRYVAGRLHVWSLWKDT------LVRRGY-QYGQYLRTVQTKVTN 139 Query: 444 DIYE--VIMKNAARLDSE---IIXXXXXXXXXXXXKTLERSYLLKLGGVVVERPQHMLMR 608 Y+ ++ + L I L YLL E PQ L+ Sbjct: 140 GEYDSRILTYSEGELQEAGCWINSDWDTDYDYAGAVLLTSRYLLPN-----ELPQEALLT 194 Query: 609 -----VSVGIHKDDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSI 773 SV + A R Y ++ R + A+P L N P L+SCF++ M +D++ Sbjct: 195 CALLLASVEAPDRRLQWARRFYESIAARRISLATPILANLRVPGGSLTSCFIVAM-EDNL 253 Query: 774 EGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQ 953 E I+ + A ISK+ GG+GV+V IRATGS++ G S G++P ++ NDTA V+Q Sbjct: 254 ESIFGEITNAARISKNGGGVGVNVSRIRATGSWVMGKPNASGGVIPWTKLLNDTAIAVNQ 313 Query: 954 GGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDW 1133 GG+R GA V L+ WH D+ EFL+++ +G + +A D+F L +PD FM+RV N EDW Sbjct: 314 -GGRRAGAVTVGLDVWHLDVPEFLEMQAENGDQRRKAYDIFPQLILPDEFMRRVINKEDW 372 Query: 1134 S---PFCPNEAPG--LADCWGXXXXXXXXXXXXXXXXXXV----IPAQTLWFDILKAQIE 1286 + P+ E G LA+ WG I A+ L+ I++ Q+E Sbjct: 373 TLVDPYEVREKMGIELAELWGEQFEGAYREIESNLDTTITLYKRINARELFKQIMRTQVE 432 Query: 1287 TGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETA-VCNLASIALPRFVREK 1463 TG PY+ +KD+ N+ + ++LG I +NLC E +P + A CNL S+ L Sbjct: 433 TGMPYLSFKDTINKANPNKHLGYIPGTNLCCESFSNVTPGQDAHCCNLVSLNLAN----- 487 Query: 1464 GVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHR 1643 D + V+ L+ IE+ P A+ N ++R Sbjct: 488 ---------------------LDLQDIAGVSQIAVRMLDNTIELTAPPFADAKSHNNKYR 526 Query: 1644 PIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGS 1823 IG+G GLAD + +D E +NR +FE I Y G Y + GS Sbjct: 527 TIGVGAMGLADWLAKRRLNYD--ELADINR-LFEEIGYWCTQSSMELAKERGAYPAFPGS 583 Query: 1824 PVSKGII---QPDMW---NVVPSTRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGN 1985 KG++ +P W N RW L I G+RNS + A P S+S + G Sbjct: 584 DWQKGLLIGSKPVSWFQANAAKPERWE--KLSNDIQTHGIRNSHITAIAPNTSSSLVQGC 641 Query: 1986 NECFEPYTSNIY 2021 P S + Sbjct: 642 TASILPVYSRFF 653
>P08543:RIR1_HHV11 Ribonucleoside-diphosphate reductase large chain - Human herpesvirus| 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) Length = 1137 Score = 219 bits (559), Expect = 4e-56 Identities = 173/611 (28%), Positives = 277/611 (45%), Gaps = 28/611 (4%) Frame = +3 Query: 657 YHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLKE--CAVISKSAGG 830 +H + ++P + N GT SSC+L+ + + + + A+++++ GG Sbjct: 554 FHRLYDHQIVPSTPAMLNLGTRNYYTSSCYLVNPQATTNKATLRAITSNVSAILARN-GG 612 Query: 831 IGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHAD 1010 IG+ V +G GT++ ++P L+V + ++ + GA VYLEPWH D Sbjct: 613 IGLCVQAFNDSGP------GTAS-VMPALKVLDSLVAAHNKESARPTGA-CVYLEPWHTD 664 Query: 1011 IFEFLDLRKN-HGKEENRARDLFFALWVPDLFMQRV------QNNEDWSPFCPNEAPGLA 1169 + L ++ G+E R ++F ALW+PDLF +R+ + N W+ F + + LA Sbjct: 665 VRAVLRMKGVLAGEEAQRCDNIFSALWMPDLFFKRLIRHLDGEKNVTWTLFDRDTSMSLA 724 Query: 1170 DCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNL 1349 D G IP Q L + I+++ TG+P++++KD+ NR Sbjct: 725 DFHGEEFEKLYQHLEVMGFGEQ-IPIQELAYGIVRSAATTGSPFVMFKDAVNRHYIYDTQ 783 Query: 1350 GT-IKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRY 1526 G I SNLCTEI+ S + VCNL S+ L R V + Sbjct: 784 GAAIAGSNLCTEIVHPASKRSSGVCNLGSVNLARCV--------------------SRQT 823 Query: 1527 FDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFD 1706 FDF +L + +N +I+ P R N R +GIG+QGL + LG+ + Sbjct: 824 FDFGRLRDAVQACVLMVNIMIDSTLQPTPQCTRGNDNLRSMGIGMQGLHTACLKLGLDLE 883 Query: 1707 SPEAQQLNRDIFETIYYHXXXXXXXXXXXXG-PYETYEGSPVSKGIIQPDMWNVVPSTR- 1880 S E Q LN+ I E + P+ ++ S G W P R Sbjct: 884 SAEFQDLNKHIAEVMLLSAMKTSNALCVRGARPFNHFKRSMYRAGRFH---WERFPDARP 940 Query: 1881 ---WNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFV 2051 W LR+++ K G+RNS VA MPTA+++QI +E F P +N++S+ GE + Sbjct: 941 RYEGEWEMLRQSMMKHGLRNSQFVALMPTAASAQISDVSEGFAPLFTNLFSKVTRDGETL 1000 Query: 2052 VVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAI--------YKTVWEIK 2207 N LL +L T + K + D K + L + +KT ++ Sbjct: 1001 RPNTLLLKELER----TFSGKRLLEVMDSLDAKQWSVAQALPCLEPTHPLRRFKTAFDYD 1056 Query: 2208 QKTLVDMAVDRGCYIDQSQSLNVHMDQP-----NFAKLTSLHFHAWSKGLKTGMYYLRTR 2372 QK L+D+ DR Y+D SQS+ +++ + + L L HA+ +GLKTGMYY + R Sbjct: 1057 QKLLIDLCADRAPYVDHSQSMTLYVTEKADGTLPASTLVRLLVHAYKRGLKTGMYYCKVR 1116 Query: 2373 AAADAIKFTVD 2405 A ++ F D Sbjct: 1117 KATNSGVFGGD 1127
>P09853:RIR1_HHV23 Ribonucleoside-diphosphate reductase large chain - Human herpesvirus| 2 (strain 333) (HHV-2) (Human herpes simplex virus 2) Length = 1144 Score = 215 bits (547), Expect = 9e-55 Identities = 169/607 (27%), Positives = 275/607 (45%), Gaps = 24/607 (3%) Frame = +3 Query: 657 YHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTLK-ECAVISKSAGGI 833 +H + ++P + N GT SSC+L+ + + + + + I GGI Sbjct: 561 FHRLYDHQIVPSTPAMLNLGTRNYYTSSCYLVNPQATTNQATLRAITGNVSAILARNGGI 620 Query: 834 GVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADI 1013 G+ + ++ + GT++ I+P L+V + ++ + GA VYLEPWH+D+ Sbjct: 621 GLCMQ------AFNDASPGTAS-IMPALKVLDSLVAAHNKQSTRPTGA-CVYLEPWHSDV 672 Query: 1014 FEFLDLRKN-HGKEENRARDLFFALWVPDLFMQRV------QNNEDWSPFCPNEAPGLAD 1172 L ++ G+E R ++F ALW+PDLF +R+ + N WS F + + LAD Sbjct: 673 RAVLRMKGVLAGEEAQRCDNIFSALWMPDLFFKRLIRHLDGEKNVTWSLFDRDTSMSLAD 732 Query: 1173 CWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLG 1352 G IP Q L + I+++ TG+P++++KD+ NR G Sbjct: 733 FHGEEFEKLYEHLEAMGFGE-TIPIQDLAYAIVRSAATTGSPFIMFKDAVNRHYIYDTQG 791 Query: 1353 T-IKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYF 1529 I SNLCTEI+ +S + VCNL S+ L R V R F Sbjct: 792 AAIAGSNLCTEIVHPSSKRSSGVCNLGSVNLARCV--------------------SRRTF 831 Query: 1530 DFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDS 1709 DF L + +N +I+ P R + R +GIG+QGL + +G+ +S Sbjct: 832 DFGMLRDAVQACVLMVNIMIDSTLQPTPQCARGHDNLRSMGIGMQGLHTACLKMGLDLES 891 Query: 1710 PEAQQLNRDIFETIYYHXXXXXXXXXXXXG-PYETYEGSPVSKGIIQPDMW-NVVPSTRW 1883 E + LN I E + P+ ++ S G + + N P Sbjct: 892 AEFRDLNTHIAEVMLLAAMKTSNALCVRGARPFSHFKRSMYRAGRFHWERFSNASPRYEG 951 Query: 1884 NWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNK 2063 W LR+++ K G+RNS +A MPTA+++QI +E F P +N++S+ GE + N Sbjct: 952 EWEMLRQSMMKHGLRNSQFIALMPTAASAQISDVSEGFAPLFTNLFSKVTRDGETLRPNT 1011 Query: 2064 HLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAI--------YKTVWEIKQKTL 2219 LL +L T K + DG K + L + +KT ++ Q+ L Sbjct: 1012 LLLKELER----TFGGKRLLDAMDGLEAKQWSVAQALPCLDPAHPLRRFKTAFDYDQELL 1067 Query: 2220 VDMAVDRGCYIDQSQSLNVHMDQP-----NFAKLTSLHFHAWSKGLKTGMYYLRTRAAAD 2384 +D+ DR Y+D SQS+ +++ + + L L HA+ +GLKTGMYY + R A + Sbjct: 1068 IDLCADRAPYVDHSQSMTLYVTEKADGTLPASTLVRLLVHAYKRGLKTGMYYCKVRKATN 1127 Query: 2385 AIKFTVD 2405 + F D Sbjct: 1128 SGVFAGD 1134
>P09248:RIR1_VZVD Ribonucleoside-diphosphate reductase large chain - Varicella-zoster| virus (strain Dumas) (HHV-3) (Human herpesvirus 3) Length = 775 Score = 214 bits (544), Expect = 2e-54 Identities = 162/592 (27%), Positives = 277/592 (46%), Gaps = 26/592 (4%) Frame = +3 Query: 690 ASPTLFNAGTPRPQLSSCFLICMKDDSI-EGIYDTLKECAVISKSAGGIGVSVHNIRATG 866 A+P + G +SC+L+ + ++ + + + +S GG+G+S+ ++ Sbjct: 199 ATPVMMFLGRETGATASCYLMDPESITVGRAVRAITGDVGTVLQSRGGVGISLQSLN--- 255 Query: 867 SYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHG 1046 + T + G++ +L++ + ++ + G VY+EPWH D+ L R Sbjct: 256 --LIPTENQTKGLLAVLKLLDCMVMAINSDCERPTGV-CVYIEPWHVDLQTVLATRGMLV 312 Query: 1047 KEEN-RARDLFFALWVPDLFMQRV------QNNEDWSPFCPNEAPGLADCWGXXXXXXXX 1205 ++E R ++F LW PDLF +R +N W+ F N A L G Sbjct: 313 RDEIFRCDNIFCCLWTPDLFFERYLSYLKGASNVQWTLF-DNRADILRTLHGEAFTSTYL 371 Query: 1206 XXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGT-IKSSNLCTE 1382 +P Q + F I+++ TG+P++++KD+CNR + G I SNLCTE Sbjct: 372 RLEREGLGVSSVPIQDIAFTIIRSAAVTGSPFLMFKDACNRNYHMNTQGNAITGSNLCTE 431 Query: 1383 IIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTST 1562 I++ + VCNLASI L + + V F+ + L T Sbjct: 432 IVQKADAHQHGVCNLASINLTTCLSKGPVS------------------FNLNDLQLTART 473 Query: 1563 VTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIF 1742 LN ++ +P + + + +R +GIG+QGL T + LG S A++LN I Sbjct: 474 TVIFLNGVLAAGNFPCKKSCKGVKNNRSLGIGIQGLHTTCLRLGFDLTSQPARRLNVQIA 533 Query: 1743 ETIYYHXXXXXXXXXXXXG--PYETYEGSPVSKGIIQPDMWNVVPSTRWNWPTLRETIAK 1916 E + Y G P++ + S +KG + D ++ + W TLR+ I Sbjct: 534 ELMLYETMKTSMEMCKIGGLAPFKGFTESKYAKGWLHQDGFSTISYLDLPWCTLRDDICA 593 Query: 1917 VGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEM-- 2090 G+ NS +A MPT S++Q+ +E F P +N++S+ SGE + N L+ +L +M Sbjct: 594 YGLYNSQFLALMPTVSSAQVTECSEGFSPIYNNMFSKVTTSGELLRPNLDLMDELRDMYS 653 Query: 2091 ------GIWTPALKNK--IIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGC 2246 + KN+ +I G + + LK YKT +E +Q+ LVDM +R Sbjct: 654 CEEKRLEVINILEKNQWSVIRSFGCLSNSHPL---LK--YKTAFEYEQEDLVDMCAERAP 708 Query: 2247 YIDQSQSLNVHMDQ-PN----FAKLTSLHFHAWSKGLKTGMYYLRTRAAADA 2387 +IDQSQS+ + +++ P+ +K+ +L A+ GLKTGMYY + R A ++ Sbjct: 709 FIDQSQSMTLFIEERPDGTIPASKIMNLLIRAYKAGLKTGMYYCKIRKATNS 760
>Q01037:RIR1_SHV21 Ribonucleoside-diphosphate reductase large chain - Saimiriine| herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri) Length = 767 Score = 209 bits (532), Expect = 5e-53 Identities = 177/644 (27%), Positives = 280/644 (43%), Gaps = 15/644 (2%) Frame = +3 Query: 657 YHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGIYDTL-KECAVISKSAGGI 833 Y ++S + A+P + +AG LSSCF+I D+ + ++ E A + S G+ Sbjct: 164 YKVISSQLVCCATPVMRSAGVAGENLSSCFIIAPTLDTEKSTISSIFGELAPLLASRSGV 223 Query: 834 GVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADI 1013 GV V G I N V FND + R + A Y+E WH I Sbjct: 224 GVDVTKFSFGGKNIHSCLKLINAQVEF---FNDKS--------VRPVSVATYIEVWHCQI 272 Query: 1014 FEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNED--WSPFCPNEAPGLADCWGXX 1187 EFL + + R +F + VP LF + +++ + W F P +AP L +G Sbjct: 273 HEFLSAKLPENPD--RCNSIFQGVCVPSLFFKMYESDPNGLWYLFDPQDAPNLTRLYGLE 330 Query: 1188 XXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLG-TIKS 1364 + ++L F ++ I+TG+PY++ K++ N+ + G I Sbjct: 331 FEEEYLRLVSEKKYKQSVTLKSLMFSLINTIIKTGSPYVISKEAMNKHHWYETQGEAINC 390 Query: 1365 SNLCTEIIEFTSPEE-TAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDK 1541 SNLC EI++ P++ T+ CNLA++ LP+ + P S FDF K Sbjct: 391 SNLCAEIVQ--QPKQFTSTCNLANVCLPKCLNSSNFPYTC----------SNTAQFDFSK 438 Query: 1542 LGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQ 1721 L F +N I ++ P +A R R +GIG GLAD F +G + E++ Sbjct: 439 LEYAVQAAVFIINACI-LSPSPTSSAT-VGQRERSMGIGCHGLADVFSEMGYGYLDLESE 496 Query: 1722 QLNRDIFETIYYHXXXXXXXXXXXXG--PYETYEGSPVSKGIIQPDMWNVVPST--RWNW 1889 L+RDIFET+YY P+ + S ++ G+ W+ +P W Sbjct: 497 CLDRDIFETMYYTAVKTSSEICSVGKGQPFAGFRKSKLAHGVFHWATWDAMPQRVPMKQW 556 Query: 1890 PTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHL 2069 L++ I K GV NS +A MPTA TSQ+ G + F PY +N+ S+ E + N Sbjct: 557 IHLQDNIKKFGVFNSQFIALMPTAGTSQLTGYTDSFYPYFANMSSKVSNKEEIMKPNITF 616 Query: 2070 LHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYK---TVWEIKQKTLVDMAVDR 2240 L ++ + T + + G + M P+D+ YK T ++ + + A R Sbjct: 617 LKNVKPQDLCT------VRFYGGDVSMM---PEDVSTRYKHFLTAFDYCPEAQMRRASIR 667 Query: 2241 GCYIDQSQSLNVHMDQPNFAK---LTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTG 2411 Y+DQSQSL + + + N L L + GLKT MYY R + ++ Sbjct: 668 APYVDQSQSLTLFLTEENVQSAKYLKDLLLLGFRLGLKTIMYYCRVKKTTKLLQLEC--- 724 Query: 2412 FLKVXXXXXXXXXXXXXKLAEEDDEAKMAQVVCSLNNREECLAC 2543 LK+ LA E ++ + C L ++ EC+AC Sbjct: 725 -LKLDEHTKKDAQIVLADLARELPDSHKTEDACPL-DQSECIAC 766
>P43754:RIR1_HAEIN Ribonucleoside-diphosphate reductase alpha subunit - Haemophilus| influenzae Length = 756 Score = 189 bits (479), Expect = 7e-47 Identities = 194/816 (23%), Positives = 321/816 (39%), Gaps = 42/816 (5%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQL-DXX 266 + V KRDG E ++ DKI + + GL V + + Y+G+ TS + + Sbjct: 5 LMVTKRDGTQEQINLDKIHRVITWAAEGLDNVSVSQVELRSHI--QFYEGIRTSDIHETI 62 Query: 267 XXXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAED 446 PDY LAAR+A+ +L K F +Y H + L+ + Sbjct: 63 IKAAADLISKDSPDYQYLAARLAIFHLRKKAYGHFDPP--RLYDHVKK-------LVRME 113 Query: 447 IYE-VIMKNAAR-----LDSEIIXXXXXXXXXXXXKTLERSYLL--KLGGVVVERPQHML 602 Y+ ++ + R +D I K LE YL+ ++ G + E Q + Sbjct: 114 KYDQALLDDYTREEWDTMDGFIDHWRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLY 173 Query: 603 MRVSVGIH-----KDDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLI-CMKD 764 + VS + + +D R Y S + +P + TP Q SSC LI C D Sbjct: 174 LLVSASLFSKYPKETRLDYVKRFYDATSTFKISLPTPIMAGVRTPTRQFSSCVLIEC--D 231 Query: 765 DSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARY 944 DS++ I T GIG++ IRA GS IRG G +P + F + Sbjct: 232 DSLDSINATASAIVKYVSQRAGIGINAGAIRALGSEIRGGEAFHTGCIPFYKYFQTAVKS 291 Query: 945 VDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNN 1124 QGG R GA +Y WH + L L+ N G E+NR R + + + + L QR+ Sbjct: 292 CSQGG-VRGGAATLYYPIWHLEAENLLVLKNNRGVEDNRVRHMDYGVQLNKLMYQRLIKG 350 Query: 1125 EDWSPFCPNEAPGLADCWGXXXXXXXXXXXXXXXXXXV----IPAQTLWFDILKAQIETG 1292 + + F P++ PGL + + + + A ++ +++ + TG Sbjct: 351 SEITLFSPSDVPGLYEAFFADQDKFEELYVKYEQDPTIRKRTVKAVEIFSLLMQERASTG 410 Query: 1293 TPYMLYKDSCNRKSN-QQNLGTIKSSNLCTEIIEFTSP--------EETAVCNLASIALP 1445 Y+ D CN S + ++ SNLC EI T P E A+C L++ L Sbjct: 411 RIYIQNVDHCNTHSPFDPQVAPVRQSNLCLEIALPTKPLQHINDENGEIALCTLSAFNL- 469 Query: 1446 RFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARR 1625 + + D+L E+ +L+ +++ YPV A+R Sbjct: 470 ------------------------GKIENLDELEELADLAVRSLDALLDYQDYPVVAAKR 505 Query: 1626 SNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPY 1805 S++ R +GIGV A G+ + A L FE I Y+ G Sbjct: 506 SSLARRSLGIGVINYAYYLAKNGVRYSDGSANDLTHRTFEAIQYYLLKASMNLAKEQGAC 565 Query: 1806 ETYEGSPVSKGIIQPDMWN------VVPSTRWNWPTLRETIAKVGVRNSLLVAPMPTAST 1967 E + + +KGI+ D + ++W +LR+ I + G+RNS L A MP+ ++ Sbjct: 566 EYFNETTYAKGILPIDTYKKDLDSLTQEPLHYDWESLRKDIQEFGLRNSTLTALMPSETS 625 Query: 1968 SQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQ 2147 SQI EP ++ + +DG ++ Sbjct: 626 SQISNATNGIEPPRGHVSIK--------------------------------ASKDGILK 653 Query: 2148 KMEEIPDDLKAIYKTVWEIKQKT-LVDMAVDRGCYIDQSQSLNVHMDQPNFAK------- 2303 ++ ++L Y+ +W+I + + ++DQ+ S N + D F Sbjct: 654 QVVPEYENLMDNYELLWDIPSNDGYLHLVGIMQKFVDQAISANTNYDPKRFEDGKVPMKV 713 Query: 2304 LTSLHFHAWSKGLKTGMYYLRTRAAADAIKFTVDTG 2411 L A+ GLKT +YY TR A+ ++ +D G Sbjct: 714 LLKDLLTAYKYGLKT-LYYQNTRDGAEDVQEDLDDG 748
>P37426:RIR1_SALTY Ribonucleoside-diphosphate reductase 1 subunit alpha - Salmonella| typhimurium Length = 761 Score = 187 bits (474), Expect = 3e-46 Identities = 197/801 (24%), Positives = 308/801 (38%), Gaps = 36/801 (4%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQL-DXX 266 + V KRDGRTE ++ DKI L + GL+ V + + Y G+ TS + + Sbjct: 5 LLVTKRDGRTERINLDKIHRVLDWAAEGLNNVSVSQVELRSHI--QFYDGIKTSDIHETI 62 Query: 267 XXXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAED 446 PDY LAAR+A+ +L K F ++ G + ED Sbjct: 63 IKAAADLISRDAPDYQYLAARLAIFHLRKKAFGQFEPPALYHHVVKMVELGKYDNHLLED 122 Query: 447 IYEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLL--KLGGVVVERPQHMLMRVSVG 620 E K ++DS I+ K LE YL+ ++ G + E Q + + V+ Sbjct: 123 YTEEEFK---QMDSFIVHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAAC 179 Query: 621 IHKD-----DIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLI-CMKDDSIEGI 782 + + +D R Y +S + +P + TP Q SSC LI C DS++ I Sbjct: 180 LFSNYPRETRLDYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIEC--GDSLDSI 237 Query: 783 YDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGG 962 T GIG++ IRA GS IRG G +P + F + QGG Sbjct: 238 NATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGG- 296 Query: 963 KRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPF 1142 R GA ++ WH ++ L L+ N G E NR R + + + + L R+ D + F Sbjct: 297 VRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGGDITLF 356 Query: 1143 CPNEAPGLADCWGXXXXXXXXXXXXXXXXXXV----IPAQTLWFDILKAQIETGTPYMLY 1310 P++ PGL D + + + A L+ +++ + TG Y+ Sbjct: 357 SPSDVPGLYDAFFADQDEFERLYVKYEHDDSIRKQRVKAVELFSLMMQERASTGRIYIQN 416 Query: 1311 KDSCNRKSN-QQNLGTIKSSNLCTEIIEFTSP--------EETAVCNLASIALPRFVREK 1463 D CN S + ++ SNLC EI T P E A+C L++ L Sbjct: 417 VDHCNTHSPFDPVVAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNL------- 469 Query: 1464 GVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHR 1643 D+L E+ L+ +++ YP+ A+R M R Sbjct: 470 ------------------GAIKTLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRR 511 Query: 1644 PIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGS 1823 +GIGV A G + A L FE I Y+ G + + Sbjct: 512 TLGIGVINFAYWLAKNGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNET 571 Query: 1824 PVSKGIIQPDMWN------VVPSTRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGN 1985 +KGI+ D + V ++W LRE+I G+RNS L A MP+ ++SQI Sbjct: 572 TYAKGILPIDTYKKDLDAIVNEPLHYDWEQLRESIKTHGLRNSTLSALMPSETSSQISNA 631 Query: 1986 NECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIP 2165 EP + + +DG ++++ Sbjct: 632 TNGIEPPRGYVSIK--------------------------------ASKDGILRQVVPDY 659 Query: 2166 DDLKAIYKTVWEIKQKT-LVDMAVDRGCYIDQSQSLNVHMDQPNF-------AKLTSLHF 2321 + LK Y+ +WE+ + + +IDQS S N + D F +L Sbjct: 660 EHLKDAYELLWEMPNNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLL 719 Query: 2322 HAWSKGLKTGMYYLRTRAAAD 2384 A+ G+KT +YY TR A+ Sbjct: 720 TAYKFGVKT-LYYQNTRDGAE 739
>P00452:RIR1_ECOLI Ribonucleoside-diphosphate reductase 1 subunit alpha - Escherichia| coli Length = 761 Score = 184 bits (467), Expect = 2e-45 Identities = 206/803 (25%), Positives = 315/803 (39%), Gaps = 38/803 (4%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQL-DXX 266 + V KRDG TE ++ DKI L + GL V + + Y G+ TS + + Sbjct: 5 LLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHI--QFYDGIKTSDIHETI 62 Query: 267 XXXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAED 446 PDY LAAR+A+ +L K F ++ G + ED Sbjct: 63 IKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLED 122 Query: 447 IYEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLL--KLGGVVVERPQHMLMRVSVG 620 E K ++D+ I K LE YL+ ++ G + E Q + + V+ Sbjct: 123 YTEEEFK---QMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAAC 179 Query: 621 IHKD-----DIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLI-CMKDDSIEGI 782 + + + R Y +S + +P + TP Q SSC LI C DS++ I Sbjct: 180 LFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIEC--GDSLDSI 237 Query: 783 YDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGG 962 T GIG++ IRA GS IRG G +P + F + QGG Sbjct: 238 NATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGG- 296 Query: 963 KRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPF 1142 R GA ++ WH ++ L L+ N G E NR R + + + + L R+ ED + F Sbjct: 297 VRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLF 356 Query: 1143 CPNEAPGLADCWGXXXXXXXXXXXXXXXXXXV----IPAQTLWFDILKAQIETGTPYMLY 1310 P++ PGL D + + + A L+ +++ + TG Y+ Sbjct: 357 SPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQN 416 Query: 1311 KDSCNRKSN-QQNLGTIKSSNLCTEIIEFTSP--------EETAVCNLASIALPRFVREK 1463 D CN S + ++ SNLC EI T P E A+C L++ L Sbjct: 417 VDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNL------- 469 Query: 1464 GVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHR 1643 G+ N + D+L E+ L+ +++ YP+ A+R M R Sbjct: 470 ---------------GAIN---NLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRR 511 Query: 1644 PIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGS 1823 +GIGV A G + A L FE I Y+ G + + Sbjct: 512 TLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNET 571 Query: 1824 PVSKGIIQPDMWNVVPST------RWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGN 1985 +KGI+ D + T ++W LRE+I G+RNS L A MP+ ++SQI Sbjct: 572 TYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNA 631 Query: 1986 NECFEP---YTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKME 2156 EP Y S S+ + + V +H LHD E+ +W ++ DG +Q + Sbjct: 632 TNGIEPPRGYVSIKASKDGILRQVVPDYEH-LHDAYEL-LW------EMPGNDGYLQLV- 682 Query: 2157 EIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVHMDQPNF-------AKLTSL 2315 I QK +IDQS S N + D F +L Sbjct: 683 --------------GIMQK-----------FIDQSISANTNYDPSRFPSGKVPMQQLLKD 717 Query: 2316 HFHAWSKGLKTGMYYLRTRAAAD 2384 A+ G+KT +YY TR A+ Sbjct: 718 LLTAYKFGVKT-LYYQNTRDGAE 739
>Q8K9W3:RIR1_BUCAP Ribonucleoside-diphosphate reductase alpha subunit - Buchnera| aphidicola subsp. Schizaphis graminum Length = 763 Score = 177 bits (448), Expect = 3e-43 Identities = 197/801 (24%), Positives = 317/801 (39%), Gaps = 36/801 (4%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQL-DXX 266 ++V KR+G+ E ++ DKI L + GL V + ++ Y ++T + + Sbjct: 5 LFVTKRNGKKEKINLDKIHKVLNWAAKGLENISVSQVELRSRI--QFYNNISTVNIHETI 62 Query: 267 XXXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAED 446 + PDY +AAR+A+ +L K F ++Y H ++ L + Sbjct: 63 IKAAADLISENTPDYQYMAARLAIFHLRKKAYGQFEPP--NLYYHV-KKMVQLGKYDEKL 119 Query: 447 IYEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLL--KLGGVVVERPQHMLMRVSVG 620 + + ++S + K LE YLL ++ G + E Q + + +S Sbjct: 120 LQNYSFEEYVEMNSFVDHRRDMNFSYAAVKQLEAKYLLQNRVTGQIYESAQFLYILISAC 179 Query: 621 IH-----KDDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLI-CMKDDSIEGI 782 + K ++ R Y+ +S + +P + TP Q SSC LI C D++ I Sbjct: 180 LFSKYEKKVRMNYIQRFYNAISTFKISLPTPIMSGVRTPTRQFSSCVLIECA--DNLNSI 237 Query: 783 YDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGG 962 T GIG++ IRA GS IR G +P + F + QGG Sbjct: 238 NATTSAIVKYVSQRAGIGINAGQIRALGSPIRNGEAFHTGCIPFYKHFQSAVKSCSQGG- 296 Query: 963 KRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPF 1142 R GA V+ WH +I L L+ N G EENR R L +A+ + L QR+ + + F Sbjct: 297 VRGGAATVFYPIWHLEIESLLVLKNNRGIEENRVRHLDYAVQINKLMYQRMLLGQKITLF 356 Query: 1143 CPNEAPGLADCWGXXXXXXXXXXXXXXXXXXV----IPAQTLWFDILKAQIETGTPYMLY 1310 P++ P L + + + I A L+ I++ + TG Y+ + Sbjct: 357 SPSDVPKLYEFFFSDQKKFKEIYIKYEKNRNIRKKSINAIDLFCLIMRERASTGRIYIQH 416 Query: 1311 KDSCNRKSN-QQNLGTIKSSNLCTEIIEFTSP--------EETAVCNLASIALPRFVREK 1463 D CN S L TI+ SNLC EI T P E A+C L+++ L Sbjct: 417 VDHCNSHSAFNSKLATIRQSNLCLEITLPTKPLNNIDDKNGEIALCTLSALNL------- 469 Query: 1464 GVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHR 1643 G N D L E+++ L++I+E YPV A++S + R Sbjct: 470 ---------------GLIN---DLHDLKELSTLSVRALDEILEYQNYPVVCAKKSAISRR 511 Query: 1644 PIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGS 1823 +GIGV A + + A+ L FE I Y+ G + + Sbjct: 512 SLGIGVINFAYYLAKNKVRYSDGSAKNLTHKTFEAIQYYLLKASCELAKEKGSCSLFNQT 571 Query: 1824 PVSKGIIQPDMWN------VVPSTRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGN 1985 G D + NW LR+ I K G+RNS L A MP+ ++SQI Sbjct: 572 NYYLGKFPIDTYKKDIDSICNEPLHLNWNLLRKKIKKYGLRNSTLSALMPSETSSQISNA 631 Query: 1986 NECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIP 2165 EP I ++K+ +DG ++++ Sbjct: 632 TNGIEPPRGFI-----------------------------SIKSS---KDGMLRQVVPEY 659 Query: 2166 DDLKAIYKTVWEIKQKT-LVDMAVDRGCYIDQSQSLNVHMDQPNFAK----LTSLHFH-- 2324 LK+ Y+ +WEI +++ ++DQS S N + D F + L + Sbjct: 660 KKLKSEYELLWEIPNNIGYLELVAIMQKFVDQSISANTNYDPKRFLNEKIPMKQLIYDLL 719 Query: 2325 -AWSKGLKTGMYYLRTRAAAD 2384 A+ G+KT +YY TR A+ Sbjct: 720 VAYKLGIKT-LYYQNTRDGAE 739
>P57276:RIR1_BUCAI Ribonucleoside-diphosphate reductase alpha subunit - Buchnera| aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) Length = 761 Score = 175 bits (443), Expect = 1e-42 Identities = 201/809 (24%), Positives = 318/809 (39%), Gaps = 44/809 (5%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQ-KVCAGV--YKGVTTSQL- 257 ++V KRDGR E ++ DKI L S GL D V V+Q ++C+ + Y +TT + Sbjct: 5 LFVTKRDGRKEKINLDKIHKVLNWASEGL-----DDVSVSQVELCSRIQFYNNITTINIH 59 Query: 258 DXXXXXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLI 437 + PDY +AAR+A+ +L K F +Y H + L Sbjct: 60 ETIIKAAADLISQDTPDYQYMAARLAIFHLRKKAYGQFEPP--KLYDHVKKMVDL----- 112 Query: 438 AEDIYEVIMKNAA-----RLDSEIIXXXXXXXXXXXXKTLERSYLL--KLGGVVVERPQH 596 E E ++KN + +++S I K LE YL+ ++ G + E Q Sbjct: 113 -EKYDENLLKNYSYKEFLQMNSFIDHWRDMNFSYAAVKQLEGKYLIQNRVNGKIYESAQF 171 Query: 597 MLMRVSVGIHKD-----DIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLI-CM 758 + + +S + ++ R Y+ +S + +P + TP Q SSC LI C Sbjct: 172 LYILISACLFSQYPKNVRMNYIHRFYNAISTFKISLPTPIMSGVRTPTRQFSSCVLIEC- 230 Query: 759 KDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTA 938 DS+ I T GIGV+ IRA GS IR G +P + F Sbjct: 231 -GDSLNSINATTSSIVKYVSQRAGIGVNAGQIRALGSPIRNGEAFHTGCIPFYKHFQSAV 289 Query: 939 RYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQ 1118 + QGG R GA ++ WH ++ L L+ N G EENR R + +A+ + L QR+ Sbjct: 290 KSCSQGG-VRGGAATIFYPIWHLEVESLLVLKNNRGIEENRVRHIDYAIQINKLMYQRML 348 Query: 1119 NNEDWSPFCPNEAPGLADCWGXXXXXXXXXXXXXXXXXXV----IPAQTLWFDILKAQIE 1286 + + + F P++ P L + + I A L+ +++ + Sbjct: 349 SGDQITLFSPSDVPDLYKAFFSDQKKFKKIYLQYEKNKNIRKKTIKALDLFSLMMQERTS 408 Query: 1287 TGTPYMLYKDSCNRKSN-QQNLGTIKSSNLCTEIIEFT--------SPEETAVCNLASIA 1439 TG Y+ D CN S L I+ SNLC EI T + E A+C L++ Sbjct: 409 TGRIYVQNVDHCNLHSAFNPELSPIRQSNLCLEITLPTKSLNDVHDTDGEIALCTLSAFN 468 Query: 1440 LPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETA 1619 L G DF +L ++ L++I++ YPV A Sbjct: 469 L----------------------GKIKSLDDFKELSILSVRA---LDEILDYQNYPVLAA 503 Query: 1620 RRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXG 1799 ++S + R +GIGV A + + A L FE + Y+ G Sbjct: 504 KKSAISRRSLGIGVINFAYYLAKNKVRYSDGSAHNLTHKTFEAMQYYLLEASCELAKEKG 563 Query: 1800 PYETYEGSPVSKGIIQPDMWNVVPSTRWN------WPTLRETIAKVGVRNSLLVAPMPTA 1961 + + G + D + N W LR I K G+RNS L A MP+ Sbjct: 564 ACSLFNHTNYYLGKLPIDTYKKYIDDICNEPLHLDWNLLRSKIKKYGLRNSTLSALMPSE 623 Query: 1962 STSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGS 2141 ++SQI EP I + + +DG Sbjct: 624 TSSQISNATNGIEPPRGFISIK--------------------------------VSKDGI 651 Query: 2142 IQKMEEIPDDLKAIYKTVWEIKQKT-LVDMAVDRGCYIDQSQSLNVHMDQPNFAK----L 2306 ++++ L+ Y+ +W+I T + +A +IDQS S+N H D F + Sbjct: 652 LRQVVPEYKKLRLQYELLWDIPNNTGYLQLAGIMQKFIDQSISVNTHYDPARFLNNKIPM 711 Query: 2307 TSLHFH---AWSKGLKTGMYYLRTRAAAD 2384 L + ++ GLKT +YY TR ++ Sbjct: 712 KQLLYDLLLSYKLGLKT-LYYQNTRDGSE 739
>P32282:RIR1_BPT4 Ribonucleoside-diphosphate reductase subunit alpha - Bacteriophage T4| Length = 754 Score = 172 bits (435), Expect = 9e-42 Identities = 193/811 (23%), Positives = 316/811 (38%), Gaps = 40/811 (4%) Frame = +3 Query: 96 VVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQLDXXXXX 275 V+K G +++ KI +K LS+ DP + + + + + G+TT + Sbjct: 6 VIKSSGVSQSFDPQKI---IKVLSWAAEGTSVDPYELYENIKSYLRDGMTTDDIQTIVIK 62 Query: 276 XXXXXXX-SHPDYASLAARIAVSNLHKNTKKSFSETIKDMYLHYNERSGLLSPLIAEDIY 452 PDY +AAR + L K+ + ++ Y +G P Sbjct: 63 AAANSISVEEPDYQYVAARCLMFALRKHVYGQYEPRSFIDHISYCVNAGKYDP------- 115 Query: 453 EVIMKNAAR----LDSEIIXXXXXXXXXXXXKTLERSYLLK--LGGVVVERPQHMLMRVS 614 E++ K +A L+S+I L+ YL+K G + E PQ M + Sbjct: 116 ELLSKYSAEEITFLESKIKHERDMEFTYSGAMQLKEKYLVKDKTTGQIYETPQFAFMTIG 175 Query: 615 VGIHKDD----IDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDSIEGI 782 + +H+D+ + IR Y +S R + +P + TP Q SSC +I DS++ I Sbjct: 176 MALHQDEPVDRLKHVIRFYEAVSTRQISLPTPIMAGCRTPTRQFSSCVVI-EAGDSLKSI 234 Query: 783 YDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGG 962 GIG++V IRA GS I G++P + F + QGG Sbjct: 235 NKASASIVEYISKRAGIGINVGMIRAEGSKIGMGEVRHTGVIPFWKHFQTAVKSCSQGG- 293 Query: 963 KRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPF 1142 R GA Y WH ++ L L+ N G EENR R + + + + DL M+R N+ + F Sbjct: 294 IRGGAATAYYPIWHLEVENLLVLKNNKGVEENRIRHMDYGVQLNDLMMERFGKNDYITLF 353 Query: 1143 CPNEAPG-LADCWGXXXXXXXXXXXXXXXXXXV----IPAQTLWFDILKAQIETGTPYML 1307 P+E G L + + I A+ L+ ++ + T Y+ Sbjct: 354 SPHEMGGELYYSYFKDQDRFRELYEAAEKDPNIRKKRIKARELFELLMTERSGTARIYVQ 413 Query: 1308 YKDSCNRKSN-QQNLGTIKSSNLCTEII----EFTSPE-ETAVCNLASIALPRFVREKGV 1469 + D+ N + + I+ SNLC EI + SP+ E +C L++ L F Sbjct: 414 FIDNTNNYTPFIREKAPIRQSNLCCEIAIPTNDVNSPDAEIGLCTLSAFVLDNF------ 467 Query: 1470 PIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPI 1649 + D DK+ E+ L+ +++ YPV A ++ R R + Sbjct: 468 -----------------DWQDQDKINELAEVQVRALDNLLDYQGYPVPEAEKAKKR-RNL 509 Query: 1650 GIGVQGLADTFMLLGMPFDSPE-AQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSP 1826 G+GV A L F S E A L ++FE + Y GP E Y + Sbjct: 510 GVGVTNYA---AWLASNFASYEDANDLTHELFERLQYGLIKASIKLAKEKGPSEYYSDTR 566 Query: 1827 VSKGIIQPDMWN------VVPSTRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNN 1988 S+G + D +N P +W LRE + G+RNS L A MP S+SQ+ + Sbjct: 567 WSRGELPIDWYNKKIDQIAAPKYVCDWSALREDLKLFGIRNSTLSALMPCESSSQVSNST 626 Query: 1989 ECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPD 2168 +EP + + G F V ++ H++ Sbjct: 627 NGYEPPRGPVSVKESKEGSFNQVVPNIEHNID---------------------------- 658 Query: 2169 DLKAIYKTVWEIKQK----TLVDMAVDRGCYIDQSQSLNVHMDQPNFAK-------LTSL 2315 +Y W++ +K L +A+ ++ QS S N + D F K + Sbjct: 659 ----LYDYTWKLAKKGNKPYLTQVAIMLK-WVCQSASANTYYDPQIFPKGKVPMSIMIDD 713 Query: 2316 HFHAWSKGLKTGMYYLRTRAAADAIKFTVDT 2408 + W G+K YY TR + + ++T Sbjct: 714 MLYGWYYGIK-NFYYHNTRDGSGTDDYEIET 743
>P03190:RIR1_EBV Ribonucleoside-diphosphate reductase large chain - Epstein-Barr virus| (strain B95-8) (HHV-4) (Human herpesvirus 4) Length = 826 Score = 170 bits (431), Expect = 3e-41 Identities = 156/629 (24%), Positives = 275/629 (43%), Gaps = 35/629 (5%) Frame = +3 Query: 603 MRVSVGIHKDDIDSAIRTY-----HLMSQRWFTHASPTLFNAGTPRPQLSSCFL----IC 755 +R ++ + +I+S + + HL SQ ++P + AG L+SC L + Sbjct: 137 LRAALQRARPEIESDMEVFDYYFEHLTSQT-VCCSTPFMRFAGVENSTLASCILTTPDLS 195 Query: 756 MKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDT 935 + D + +Y L G+GV V G +I ++R+ N Sbjct: 196 SEWDVTQALYRHLGRYLF---QRAGVGVGVTGAGQDGKHIS----------LLMRMINSH 242 Query: 936 ARYVDQGGGKRKGAFAVYLEPWHADIFEFLD--LRKNHGKEENRARDLFFALWVPDLFMQ 1109 Y + G KR + A Y+EPWH+ IF+FL+ L +NH R +F L+VP+LF + Sbjct: 243 VEYHNYGC-KRPVSVAAYMEPWHSQIFKFLETKLPENH----ERCPGIFTGLFVPELFFK 297 Query: 1110 RVQNN--EDWSPFCPNEAPGLADCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQI 1283 ++ DW F P +A L +G + ++L F I+ + Sbjct: 298 LFRDTPWSDWYLFDPKDAGDLERLYGEEFEREYYRLVTAGKFCGRVSIKSLMFSIVNCAV 357 Query: 1284 ETGTPYMLYKDSCNRKSNQQNLG-TIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVRE 1460 + G+P++L K++CN + G + ++NLC E+++ S + A CNLA+I LPR + Sbjct: 358 KAGSPFILLKEACNAHFWRDLQGEAMNAANLCAEVLQ-PSRKSVATCNLANICLPRCLVN 416 Query: 1461 KGVPIESHPSKLAGSN---------------GSKNRYFDFDKLGEVTSTVTFNLNKIIEM 1595 + + + + G G+ F +L + T TF + I Sbjct: 417 APLAVRAQRADTQGDELLLALPRLSVTLPGEGAVGDGFSLARLRDATQCATFVVACSILQ 476 Query: 1596 NYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXX 1775 ++ ++M G+GVQGLAD F LG + P ++ LN++IFE +Y+ Sbjct: 477 GSPTYDSRDMASM-----GLGVQGLADVFADLGWQYTDPPSRSLNKEIFEHMYFTALCTS 531 Query: 1776 XXXXXXXGP-YETYEGSPVSKGIIQPDMW--NVVPSTRWNWPTLRETIAKVGVRNSLLVA 1946 + ++ S + G W + R W L E I + G+ NS +A Sbjct: 532 SLIGLHTRKIFPGFKQSKYAGGWFHWHDWAGTDLSIPREIWSRLSERIVRDGLFNSQFIA 591 Query: 1947 PMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKII 2126 MPT+ +Q+ G ++ F P+ +N ++ E + N+ + + + Sbjct: 592 LMPTSGCAQVTGCSDAFYPFYANASTKVTNKEEALRPNRSFWRHVRLDD------REALN 645 Query: 2127 YEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVHMDQPNFAK- 2303 G + + E ++T ++ Q+ L+ M+ DR ++DQSQS ++ + + + A+ Sbjct: 646 LVGGRVSCLPEALRQRYLRFQTAFDYNQEDLIQMSRDRAPFVDQSQSHSLFLREEDAARA 705 Query: 2304 --LTSLHFHAWSKGLKTGMYYLRTRAAAD 2384 L +L ++ GLKT MYY R AAD Sbjct: 706 STLANLLVRSYELGLKTIMYYCRIEKAAD 734
>Q89AS4:RIR1_BUCBP Ribonucleoside-diphosphate reductase alpha subunit - Buchnera| aphidicola subsp. Baizongia pistaciae Length = 761 Score = 168 bits (425), Expect = 1e-40 Identities = 199/804 (24%), Positives = 318/804 (39%), Gaps = 40/804 (4%) Frame = +3 Query: 90 MYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQL-DXX 266 ++V KR+G+ E ++ DKI L + GL E+ VA K Y + T+ + + Sbjct: 5 LFVTKRNGKIELINLDKIHRVLNWAAKGL--ENISISQVALKSRIQFYNNIKTTIIHETI 62 Query: 267 XXXXXXXXXXSHPDYASLAARIAVSNLHKNTKKSFS-----ETIKDMYLHYNERSGLLSP 431 + PDY +AAR+ + +L K F+ + +K+M LL+ Sbjct: 63 IKAAADLISENSPDYQYMAARLTIFHLRKKAFGQFNPPNLYDHVKNMIKLEKYDQHLLND 122 Query: 432 LIAEDIYEVIMKNAARLDSEIIXXXXXXXXXXXXKTLERSYLL--KLGGVVVERPQHMLM 605 +D +IM +S I K LE YL+ ++ + E Q + + Sbjct: 123 YPKQDF--LIM------NSFIKHRRDMNFSYAAVKQLEGKYLIQNRVTKKIYESAQFLYI 174 Query: 606 RVSVGI-----HKDDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRPQLSSCFLICMKDDS 770 +S + ++ + Y +S + +P + TP Q SSC LI +D+ Sbjct: 175 LISACLFSKYPNETRMKYIKNFYDAISTFKISLPTPIMAGLRTPTRQFSSCVLI-ESEDN 233 Query: 771 IEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFNDTARYVD 950 + I T GIG++ IRA GS IR + G +P + F + Sbjct: 234 LNSINATTSAIVKYVSQRAGIGINAGRIRALGSPIRNGDTLHTGCIPFYKHFQSAVKSCS 293 Query: 951 QGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQNNED 1130 QGG R GA ++ WH +I L L+ N G EENR R + +++ + L QR+ E Sbjct: 294 QGG-VRGGAATIFYPIWHFEIESLLVLKNNRGIEENRVRHMDYSVQLNKLMYQRLILGEH 352 Query: 1131 WSPFCPNEAPGLADCWGXXXXXXXXXXXXXXXXXXV----IPAQTLWFDILKAQIETGTP 1298 + F P++ P L D + + + A L+ +++ + TG Sbjct: 353 ITLFSPSDVPNLYDSFFNNQEKFERLYIKYENDKTIRKKKVKASYLFSLMMQERTSTGRI 412 Query: 1299 YMLYKDSCNRKSN-QQNLGTIKSSNLCTEIIEFTSP--------EETAVCNLASIALPRF 1451 Y+ D CN S + I+ SNLC EI T E ++C L++I L Sbjct: 413 YIQNVDHCNSHSAFNPKIAPIRQSNLCLEITLPTKALQDVHDKNGEISLCTLSAINL--- 469 Query: 1452 VREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSN 1631 GS N D KL ++ + L+ +++ YP+ +A++S Sbjct: 470 -------------------GSLNNLNDLSKL---SNLIVRALDSVLDYQEYPILSAKKSA 507 Query: 1632 MRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYET 1811 + R +GIGV A G+ + A L FE I YH G Sbjct: 508 LSRRTLGIGVINFAYYLAKNGVRYSDGSANNLTHRTFEAIQYHLLNASCVLAQEKGACHW 567 Query: 1812 YEGSPVSKGIIQPDMWNVVPSTRWN------WPTLRETIAKVGVRNSLLVAPMPTASTSQ 1973 + + KGI+ D + N W LR+ I K G+RNS L A MP+ ++SQ Sbjct: 568 FSHTNYYKGILPIDTYKKNVDEICNEPLHLDWELLRKKIKKYGLRNSTLSALMPSETSSQ 627 Query: 1974 ILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKM 2153 I EP R ++S + +K DG ++++ Sbjct: 628 ISNATNGIEP------PRGLIS---IKASK-----------------------DGMLRQV 655 Query: 2154 EEIPDDLKAIYKTVWEIKQKT-LVDMAVDRGCYIDQSQSLNVHMDQ---PN----FAKLT 2309 LK Y+ +W I T + +A ++DQS S N + D PN +L Sbjct: 656 VPEYKRLKNNYELLWNIPNNTGYLQLASIMQKFVDQSISANTNYDPKLFPNNKIPMQQLI 715 Query: 2310 SLHFHAWSKGLKTGMYYLRTRAAA 2381 A+ GLKT +YY TR A Sbjct: 716 LDLLTAYKLGLKT-LYYQNTRDGA 738
>P78027:RIR1_MYCPN Ribonucleoside-diphosphate reductase alpha subunit - Mycoplasma| pneumoniae Length = 721 Score = 160 bits (406), Expect = 2e-38 Identities = 147/606 (24%), Positives = 260/606 (42%), Gaps = 42/606 (6%) Frame = +3 Query: 681 FTHASPTLFNAGTP-RPQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIR 857 F A+PT NAG R + SC+L+ + +D++E I + +SK GG+ + + NIR Sbjct: 155 FQPATPTFLNAGRKKRGEFVSCYLLRI-EDNMESIGRAITTTLQLSKRDGGVALLLTNIR 213 Query: 858 ATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRK 1037 +G+ I+ S+GI+P++++ D+ Y +Q G +R+GA AVYL H D+ +FLD ++ Sbjct: 214 ESGAPIKKIENQSSGIIPIMKLLEDSFSYANQLG-QRQGAGAVYLHAHHPDVMQFLDTKR 272 Query: 1038 NHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNEA-----PGLADCWGXXXXXXX 1202 + E+ R + L L +PD+ +NNE+ + F P + L+D Sbjct: 273 ENADEKIRIKSLSLGLVIPDITFTLAKNNEEMALFSPYDVYEEYGKPLSDI--SVTEMYY 330 Query: 1203 XXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTE 1382 I A+ + + + E+G PY+L+ D+ NR++ N I SNLC+E Sbjct: 331 ELLANQRIKKTFINARKFFQTVAELHFESGYPYILFDDTVNRRNAHPN--RIVMSNLCSE 388 Query: 1383 IIEFTSPEE------------TAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRY 1526 I++ ++P E CNL S+ + + +ES P Sbjct: 389 IVQPSTPSEFHHDLAFKKVGNDISCNLGSLNIAK-------AMESGP------------- 428 Query: 1527 FDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFD 1706 +F +L ++ ++++ + P + ++ N + +G+G L + ++ Sbjct: 429 -EFSELVKLAIESLDLVSRVSNLETAP--SIQKGNSENHALGLGAMNLHGFLATNQIYYN 485 Query: 1707 SPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGI-------IQPDMWN- 1862 SPEA F T+ YH G ++ +E + + G ++PD W Sbjct: 486 SPEAIDFTNIFFYTVAYHAFKASSELALEKGKFKNFENTKFADGSYFDKYIKVEPDFWTP 545 Query: 1863 -------------VVPSTRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEP 2003 V TR NW L I K G+ NS L+A PT S S + +P Sbjct: 546 KTERVKALFQKYQVEIPTRENWKELALNIQKNGLANSHLLAIAPTGSISYLSSCTPSLQP 605 Query: 2004 YTSNIYSRRVLSGEFVVVNKHLLHDLTEMG-IWTPALKNKIIYEDGSIQKMEEIPDDLKA 2180 S + R+ +G I+ PA ++ D Sbjct: 606 VVSPVEVRKE----------------GRLGRIYVPAY---------------QLNKDSYP 634 Query: 2181 IYKT-VWEIKQKTLVDMAVDRGCYIDQSQSLNVHM-DQPNFAKLTSLHFHAWSKGLKTGM 2354 YK +E+ + ++++A ++DQ+ SL + M D+ L + +A+ KG + + Sbjct: 635 FYKDGAYELGPEPIINIAAAAQQHVDQAISLTLFMTDKATTRDLNKAYIYAFKKGC-SSI 693 Query: 2355 YYLRTR 2372 YY+R R Sbjct: 694 YYVRVR 699
>P47473:RIR1_MYCGE Ribonucleoside-diphosphate reductase alpha subunit - Mycoplasma| genitalium Length = 721 Score = 154 bits (389), Expect = 2e-36 Identities = 153/623 (24%), Positives = 265/623 (42%), Gaps = 48/623 (7%) Frame = +3 Query: 681 FTHASPTLFNAGTP-RPQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIR 857 F A+PT NAG R + SC+L+ + +D++E I + +SK GG+ + + N+R Sbjct: 155 FQPATPTFLNAGRKKRGEFVSCYLLRI-EDNMESIGRAITTTLQLSKRDGGVALLLSNLR 213 Query: 858 ATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRK 1037 G+ I+ S+GI+P++++ D+ Y +Q G +R+GA AVYL H D+ +FLD ++ Sbjct: 214 EAGAPIKKIENQSSGIIPIMKLLEDSFSYSNQLG-QRQGAGAVYLHCHHPDVMQFLDTKR 272 Query: 1038 NHGKEENRARDLFFALWVPDLFMQRVQNNEDWSPFCPNE-----APGLADCWGXXXXXXX 1202 + E+ R + L L +PD+ Q +NNE + F P + L+D Sbjct: 273 ENADEKIRIKSLSLGLVIPDITFQLAKNNEMMALFSPYDIYQEYGKALSDI--SVTEMYY 330 Query: 1203 XXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTE 1382 I A+ + I + E+G PY+L+ D+ NR++ +N I SNLC+E Sbjct: 331 ELLENQRIKKTFISARKFFQTIAELHFESGYPYILFDDTVNRRNAHKN--RIVMSNLCSE 388 Query: 1383 IIEFTSPEE------------TAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRY 1526 I++ + P E CNL S+ + R A +GS+ Sbjct: 389 IVQPSLPSEFYSDLTFKKVGSDISCNLGSLNIAR----------------AMESGSE--- 429 Query: 1527 FDFDKLGEVTSTVTFNLNKIIEMNYYPVETA---RRSNMRHRPIGIGVQGLADTFMLLGM 1697 L E+ +L+ + ++ +ETA ++ N + +G+G L + Sbjct: 430 -----LAELIQLAIESLDLVSRIS--SLETAPSIKKGNSENHALGLGAMNLHGFLATNAI 482 Query: 1698 PFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGPYETYEGSPVSKGI-------IQPDM 1856 +DS EA F T+ YH G ++ +E + + G + D Sbjct: 483 YYDSKEAVDFTNIFFYTVAYHAFSASNKLALELGKFKDFENTKFADGSYFDKYTKVASDF 542 Query: 1857 WN--------------VVPSTRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNEC 1994 W V T+ NW L +I K G+ NS L+A PT S S + Sbjct: 543 WTCKTEKVQALFDKYQVKIPTQENWKQLVASIQKDGLANSHLMAIAPTGSISYLSSCTPS 602 Query: 1995 FEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEMG-IWTPALK----NKIIYEDGSIQKMEE 2159 +P S + R+ ++G I+ PA K N ++DG+ Sbjct: 603 LQPVVSPVEVRKE----------------GKLGRIYVPAYKLDNDNYQYFKDGA------ 640 Query: 2160 IPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSLNVHM-DQPNFAKLTSLHFHAWSK 2336 +E+ + ++++ ++DQ+ SL + M D+ L + +A+ K Sbjct: 641 ------------YELGFEPIINIVAAAQQHVDQAISLTLFMTDKATTRDLNKAYIYAFKK 688 Query: 2337 GLKTGMYYLRTRAAADAIKFTVD 2405 G + +YY+R R D +K + D Sbjct: 689 GC-SSIYYVRVR--QDVLKDSED 708
>P39452:RIR3_ECOLI Ribonucleoside-diphosphate reductase 2 alpha subunit - Escherichia| coli Length = 714 Score = 147 bits (372), Expect = 2e-34 Identities = 153/644 (23%), Positives = 251/644 (38%), Gaps = 33/644 (5%) Frame = +3 Query: 549 SYLLKL--GGVVVERPQHMLMRVSVGIHKDDIDSAIRTYHLMSQRWFTHASPTLFNAGTP 722 SY LK G +E + V++ + + D A++ M F A+PT N G Sbjct: 111 SYTLKTFDGKRYLEDFADRVTMVALTLAQGDETLALQLTDEMLSGRFQPATPTFLNCGKQ 170 Query: 723 -RPQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSN 899 R +L SCFL+ + +D++E I + +SK GG+ + N+R G+ I+ S+ Sbjct: 171 QRGELVSCFLLRI-EDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSS 229 Query: 900 GIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFF 1079 G++P++++ D Y +Q G R+GA AVYL H DI FLD ++ + E+ R + L Sbjct: 230 GVIPVMKMLEDAFSYANQLGA-RQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSL 288 Query: 1080 ALWVPDLFMQRVQNNEDWSPFCPNEAPGL-----ADCWGXXXXXXXXXXXXXXXXXXVIP 1244 + +PD+ + N + F P + + AD + Sbjct: 289 GVVIPDITFHLAKENAQMALFSPYDVERVYGKPFADV--AISQHYDELVADERIRKKYLN 346 Query: 1245 AQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETAVCN 1424 A+ + + + Q E+G PY++Y+D+ NR + G I SNLC+EI++ S E Sbjct: 347 ARDFFQRLAEIQFESGYPYIMYEDTVNRAN--PIAGRINMSNLCSEILQVNSASE----- 399 Query: 1425 LASIALPRFVREKGVPIESHPSKLAGSNGSKN--RYFDFDKLGEVTSTVTFNLNKIIEMN 1598 ++ + ++ + GS N D T L + +M+ Sbjct: 400 ----------YDENLDYTRTGHDISCNLGSLNIAHTMDSPDFARTVETAVRGLTAVSDMS 449 Query: 1599 YY-PVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXX 1775 + V + N IG+G L G+ + SPEA F I +H Sbjct: 450 HIRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYAITWHALRTS 509 Query: 1776 XXXXXXXGPYETYEG------------SPVSKGIIQPDMWNV---------VPSTRWNWP 1892 G ET+ G S +G QP V TR W Sbjct: 510 MLLARERG--ETFAGFKQSRYASGEYFSQYLQGNWQPKTAKVGELFTRSGITLPTREMWA 567 Query: 1893 TLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLL 2072 LR+ + + G+ N L A PT S S I P + + R+ Sbjct: 568 QLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRK-------------- 613 Query: 2073 HDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYI 2252 K +Y E + A+Y+ +EI + ++D + ++ Sbjct: 614 -----------EGKTGRVYYPAPFMTNENL-----ALYQDAYEIGAEKIIDTYAEATRHV 657 Query: 2253 DQSQSLNVHM-DQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAA 2381 DQ SL + D + +AW KG+KT +YY+R R A Sbjct: 658 DQGLSLTLFFPDTATTRDINKAQIYAWRKGIKT-LYYIRLRQMA 700
>Q08698:RIR3_SALTY Ribonucleoside-diphosphate reductase 2 alpha subunit - Salmonella| typhimurium Length = 714 Score = 140 bits (354), Expect = 2e-32 Identities = 149/643 (23%), Positives = 251/643 (39%), Gaps = 32/643 (4%) Frame = +3 Query: 549 SYLLKL--GGVVVERPQHMLMRVSVGIHKDDIDSAIRTYHLMSQRWFTHASPTLFNAGTP 722 SY LK G +E + + V++ + + D A + M F A+PT N G Sbjct: 111 SYTLKTFDGKRYLEHFEDRVTMVALTLAQGDETLATQLTDEMLSGRFQPATPTFLNCGKQ 170 Query: 723 -RPQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSN 899 R +L SCFL+ + +D++E I + +SK GG+ + N+R G+ I+ S+ Sbjct: 171 QRGELVSCFLLRI-EDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSS 229 Query: 900 GIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFF 1079 G++P++++ D Y +Q G R+GA AVYL H DI FLD ++ + E+ R + L Sbjct: 230 GVIPVMKMLEDAFSYANQLGA-RQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSL 288 Query: 1080 ALWVPDLFMQRVQNNEDWSPFCPNEAP---GLADCWGXXXXXXXXXXXXXXXXXXVIPAQ 1250 + +PD+ + + N + F P + G I A+ Sbjct: 289 GVVIPDITFRLAKENAQMALFSPYDIQRRYGKPFGDIAISERYDELIADPHVRKTYINAR 348 Query: 1251 TLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETAVCNLA 1430 + + + Q E+G PY++++D+ NR + G I SNLC+EI++ S Sbjct: 349 DFFQTLAEIQFESGYPYIMFEDTVNRAN--PIAGRINMSNLCSEILQVNSASR------- 399 Query: 1431 SIALPRFVREKGVPIESHPSKLAGSNGSKN--RYFDFDKLGEVTSTVTFNLNKIIEMNYY 1604 + + ++ + GS N D +G T L + +M++ Sbjct: 400 --------YDDNLDYTHIGHDISCNLGSLNIAHVMDSPDIGRTVETAIRGLTAVSDMSHI 451 Query: 1605 -PVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXX 1781 V + N IG+G L G+ + SPEA F TI +H Sbjct: 452 RSVPSIAAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYTITWHAVHTSMR 511 Query: 1782 XXXXXGPYETYEGSPVSK--------GIIQPDMW--------------NVVPSTRWNWPT 1895 G +T+ G S+ +Q D W + TR W Sbjct: 512 LARERG--KTFAGFAQSRYASGDYFTQYLQDD-WQPKTAKVRALFARSGITLPTREMWLK 568 Query: 1896 LRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLH 2075 LR+ + + G+ N L A PT S S I P + I R+ Sbjct: 569 LRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKIEIRK--------------- 613 Query: 2076 DLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYID 2255 K +Y E + +Y+ ++I + ++D + ++D Sbjct: 614 ----------EGKTGRVYYPAPFMTNENLD-----MYQDAYDIGPEKIIDTYAEATRHVD 658 Query: 2256 QSQSLNVHM-DQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAA 2381 Q SL + D + +AW KG+K+ +YY+R R A Sbjct: 659 QGLSLTLFFPDTATTRDINKAQIYAWRKGIKS-LYYIRLRQLA 700
>P0A5W8:RIR1_MYCTU Ribonucleoside-diphosphate reductase alpha subunit - Mycobacterium| tuberculosis Length = 725 Score = 138 bits (348), Expect = 1e-31 Identities = 149/650 (22%), Positives = 262/650 (40%), Gaps = 39/650 (6%) Frame = +3 Query: 549 SYLLKL--GGVVVERPQHMLMRVSVGIHKDDIDSAIRTYHLMSQRWFTHASPTLFNAGTP 722 SY LK G +ER + ++ V++ + D A + F A+PT N+G Sbjct: 122 SYTLKTFDGKRYLERFEDRVVMVALTLAAGDTALAELLVDEIIDGRFQPATPTFLNSGKK 181 Query: 723 -RPQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSN 899 R + SCFL+ + +D++E I ++ +SK GG+ + + NIR G+ I+ S+ Sbjct: 182 QRGEPVSCFLLRV-EDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQSS 240 Query: 900 GIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFF 1079 G++P++++ D Y +Q G R+GA AVYL H DI+ FLD ++ + E+ R + L Sbjct: 241 GVIPIMKLLEDAFSYANQLGA-RQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSL 299 Query: 1080 ALWVPDLFMQRVQNNED---WSPFCPNEAPGLADCWGXXXXXXXXXXXXXXXXXXVIPAQ 1250 + +PD+ + + N+D +SP+ G+ I A+ Sbjct: 300 GVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFADISVTEKYYEMVDDARIRKTKIKAR 359 Query: 1251 TLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPE-------- 1406 + + + Q E+G PY++++D+ NR + G I SNLC+EI++ ++P Sbjct: 360 EFFQTLAELQFESGYPYIMFEDTVNRANPID--GKITHSNLCSEILQVSTPSLFNEDLSY 417 Query: 1407 ----ETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFN 1574 + CNL S+ + + + DF + EV Sbjct: 418 AKVGKDISCNLGSLNIAKTMDSP----------------------DFAQTIEVAIRALTA 455 Query: 1575 LNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIY 1754 ++ + + V + + N IG+G L + + S E F T+ Sbjct: 456 VSD--QTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLARERIFYGSDEGIDFTNIYFYTVL 513 Query: 1755 YHXXXXXXXXXXXXGP-YETYEGSPVSKG---------IIQPDMWNV----------VPS 1874 YH G ++ +E S + G I +P V +P Sbjct: 514 YHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTDQIWEPKTQKVRQLFADAGIRIP- 572 Query: 1875 TRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVV 2054 T+ +W L+E++ G+ N L A PT S S I + P S + R+ G+ Sbjct: 573 TQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRK--EGKI-- 628 Query: 2055 VNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAV 2234 ++ Y + +D Y+ +EI + ++D Sbjct: 629 --------------------GRVYY------PAPYMTNDNLEYYEDAYEIGYEKIIDTYA 662 Query: 2235 DRGCYIDQSQSLNVHM-DQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAA 2381 ++DQ SL + D + +AW KG+KT +YY+R R A Sbjct: 663 AATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKT-LYYIRLRQMA 711
>P0A5W9:RIR1_MYCBO Ribonucleoside-diphosphate reductase alpha subunit - Mycobacterium| bovis Length = 725 Score = 138 bits (348), Expect = 1e-31 Identities = 149/650 (22%), Positives = 262/650 (40%), Gaps = 39/650 (6%) Frame = +3 Query: 549 SYLLKL--GGVVVERPQHMLMRVSVGIHKDDIDSAIRTYHLMSQRWFTHASPTLFNAGTP 722 SY LK G +ER + ++ V++ + D A + F A+PT N+G Sbjct: 122 SYTLKTFDGKRYLERFEDRVVMVALTLAAGDTALAELLVDEIIDGRFQPATPTFLNSGKK 181 Query: 723 -RPQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSN 899 R + SCFL+ + +D++E I ++ +SK GG+ + + NIR G+ I+ S+ Sbjct: 182 QRGEPVSCFLLRV-EDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQSS 240 Query: 900 GIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFF 1079 G++P++++ D Y +Q G R+GA AVYL H DI+ FLD ++ + E+ R + L Sbjct: 241 GVIPIMKLLEDAFSYANQLGA-RQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSL 299 Query: 1080 ALWVPDLFMQRVQNNED---WSPFCPNEAPGLADCWGXXXXXXXXXXXXXXXXXXVIPAQ 1250 + +PD+ + + N+D +SP+ G+ I A+ Sbjct: 300 GVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFADISVTEKYYEMVDDARIRKTKIKAR 359 Query: 1251 TLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPE-------- 1406 + + + Q E+G PY++++D+ NR + G I SNLC+EI++ ++P Sbjct: 360 EFFQTLAELQFESGYPYIMFEDTVNRANPID--GKITHSNLCSEILQVSTPSLFNEDLSY 417 Query: 1407 ----ETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFN 1574 + CNL S+ + + + DF + EV Sbjct: 418 AKVGKDISCNLGSLNIAKTMDSP----------------------DFAQTIEVAIRALTA 455 Query: 1575 LNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIY 1754 ++ + + V + + N IG+G L + + S E F T+ Sbjct: 456 VSD--QTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLARERIFYGSDEGIDFTNIYFYTVL 513 Query: 1755 YHXXXXXXXXXXXXGP-YETYEGSPVSKG---------IIQPDMWNV----------VPS 1874 YH G ++ +E S + G I +P V +P Sbjct: 514 YHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTDQIWEPKTQKVRQLFADAGIRIP- 572 Query: 1875 TRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVV 2054 T+ +W L+E++ G+ N L A PT S S I + P S + R+ G+ Sbjct: 573 TQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRK--EGKI-- 628 Query: 2055 VNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAV 2234 ++ Y + +D Y+ +EI + ++D Sbjct: 629 --------------------GRVYY------PAPYMTNDNLEYYEDAYEIGYEKIIDTYA 662 Query: 2235 DRGCYIDQSQSLNVHM-DQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAA 2381 ++DQ SL + D + +AW KG+KT +YY+R R A Sbjct: 663 AATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKT-LYYIRLRQMA 711
>Q9CBQ0:RIR1_MYCLE Ribonucleoside-diphosphate reductase alpha subunit - Mycobacterium| leprae Length = 721 Score = 136 bits (343), Expect = 4e-31 Identities = 149/652 (22%), Positives = 261/652 (40%), Gaps = 41/652 (6%) Frame = +3 Query: 549 SYLLKL--GGVVVERPQHMLMRVSVGIHKDDIDSAIRTYHLMSQRWFTHASPTLFNAGTP 722 SY LK G +ER + + V++ + D A + + F A+PT N+G Sbjct: 118 SYTLKTFDGKRYLERLEDRVCMVALTLAAGDTGLAEKLVDEIIDGRFQPATPTFLNSGKK 177 Query: 723 -RPQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSN 899 R + SCFL+ + +D++E I ++ +SK GG+ + + NIR G+ I+ S+ Sbjct: 178 QRGEPVSCFLLRI-EDNMESIGRSVNSALQLSKRGGGVALLLSNIREHGAPIKNIEHQSS 236 Query: 900 GIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFF 1079 G++P++++ D Y +Q G R+GA AVYL H DI+ FLD ++ + E+ R + L Sbjct: 237 GVIPIMKLLEDAFSYANQLGA-RQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSL 295 Query: 1080 ALWVPDLFMQRVQNNEDWSPFCPNEAPGL-----ADCWGXXXXXXXXXXXXXXXXXXVIP 1244 + +PD+ + + NED F + + AD I Sbjct: 296 GVIIPDITFELAKRNEDMYLFSSYDVERVYEVPFADI--SVTEKYYEMLDDARIRKTKIK 353 Query: 1245 AQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPE------ 1406 A+ + + + Q E+G PY++++D+ NR + + G I SNLC+EI++ ++P Sbjct: 354 AREFFQKLAELQFESGYPYVMFEDTVNRANPIE--GKITHSNLCSEILQVSTPSLFNDDL 411 Query: 1407 ------ETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVT 1568 + CNL S+ + + + DF + EV Sbjct: 412 SYAKVGKDISCNLGSLNIAKTMDSP----------------------DFAQTVEVAIRAL 449 Query: 1569 FNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFET 1748 ++ + + V + + N IG+G L G+ + S E F T Sbjct: 450 TAVSD--QTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLSREGIFYGSEEGVDFTNIYFYT 507 Query: 1749 IYYHXXXXXXXXXXXXGP-YETYEGSPVSKGII---------QPDMWNV----------V 1868 + +H G ++ +E S + G +P V + Sbjct: 508 VLFHVLLASNSIAIERGTFFKGFERSKYASGEFFDKYIEQTWEPKTDKVRQLFAEAAIRI 567 Query: 1869 PSTRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEF 2048 P T+ +W L+E + G+ N L A PT S S I + P S + R+ G+ Sbjct: 568 P-TQNDWKRLKELVVAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRK--EGKI 624 Query: 2049 VVVNKHLLHDLTEMGIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDM 2228 ++ Y + +D Y+ +EI + ++D Sbjct: 625 ----------------------GRVYY------PAPYMTNDNLQYYQDAYEIGYQKIIDT 656 Query: 2229 AVDRGCYIDQSQSLNVHM-DQPNFAKLTSLHFHAWSKGLKTGMYYLRTRAAA 2381 ++DQ SL + D + +AW KG+KT +YY+R R A Sbjct: 657 YAAATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKT-LYYIRLRQMA 707
>P50620:RIR1_BACSU Ribonucleoside-diphosphate reductase alpha subunit - Bacillus| subtilis Length = 700 Score = 135 bits (340), Expect = 9e-31 Identities = 138/635 (21%), Positives = 255/635 (40%), Gaps = 36/635 (5%) Frame = +3 Query: 576 VVERPQHMLMRVSVGIHKDDIDSAIRTYHLMSQRWFTHASPTLFNAGTPRP-QLSSCFLI 752 ++ER + + V++ D + A +LM + + ++PT NAG R +L SCFL+ Sbjct: 114 ILERYEDRISIVALFFANGDTEKAKEYVNLMINQEYQPSTPTFLNAGRKRRGELVSCFLL 173 Query: 753 CMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGIVPMLRVFND 932 + +DS+ I + +SK GG+ +++ +RA G I+ + G+V ++++ ++ Sbjct: 174 EV-NDSLNDISRAIDISMQLSKLGGGVSLNLSKLRAKGEAIKDVENATKGVVGVMKLLDN 232 Query: 933 TARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQR 1112 RY DQ G +R+G+ A YL +H DI +FLD +K E+ R + L + +PD F++ Sbjct: 233 AFRYADQMG-QRQGSGAAYLNIFHRDINDFLDTKKISADEDVRVKTLSIGVVIPDKFVEL 291 Query: 1113 VQNNEDWSPFCPN----EAPGLADCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQ 1280 + ++ F P+ E D + P + L + + Sbjct: 292 AREDKAAYVFYPHTIYKEYGQHMDEMDMNEMYDKFVDNPRVKKEKINPRKLL-EKLAMLR 350 Query: 1281 IETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTS-------PEETAV-----CN 1424 E+G PY++++D+ N+ ++ +K SNLC+E+++ + EE + CN Sbjct: 351 SESGYPYIMFQDNVNKVHANNHISKVKFSNLCSEVLQASQVSSYTDYDEEDEIGLDISCN 410 Query: 1425 LASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYY 1604 L S+ + + K + K D L V+ T Sbjct: 411 LGSLNILNVMEHKSI--------------EKTVKLATDSLTHVSETTDIR---------- 446 Query: 1605 PVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXX 1784 RR+N + IG+G L G+ ++SPEA+ F + ++ Sbjct: 447 NAPAVRRANKAMKSIGLGAMNLHGYLAQNGIAYESPEARDFANTFFMMVNFYSIQRSAEI 506 Query: 1785 XXXXG-PYETYEGSPVSKG---------IIQPDMWNV--------VPSTRWNWPTLRETI 1910 G ++ YEGS + G P + +P+T +W L+ + Sbjct: 507 AKEKGETFDQYEGSTYATGEYFDKYVSTDFSPKYEKIANLFEGMHIPTTE-DWKKLKAFV 565 Query: 1911 AKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFVVVNKHLLHDLTEM 2090 A+ G+ +S + PT S S + + P I R + + Sbjct: 566 AEHGMYHSYRLCIAPTGSISYVQSSTASVMPIMERIEERTYGNSK--------------- 610 Query: 2091 GIWTPALKNKIIYEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVDMAVDRGCYIDQSQSL 2270 + M + + YK +++ +VDM +IDQ S Sbjct: 611 ----------------TYYPMPGLASNNWFFYKEAYDMDMFKVVDMIATIQQHIDQGISF 654 Query: 2271 NVHM-DQPNFAKLTSLHFHAWSKGLKTGMYYLRTR 2372 + + D L + +A +G+KT +YY RT+ Sbjct: 655 TLFLKDTMTTRDLNRIDLYAHHRGIKT-IYYARTK 688
>Q6MNP6:NRDJ_BDEBA Vitamin B12-dependent ribonucleotide reductase - Bdellovibrio| bacteriovorus Length = 764 Score = 104 bits (260), Expect = 2e-21 Identities = 133/594 (22%), Positives = 228/594 (38%), Gaps = 48/594 (8%) Frame = +3 Query: 723 RPQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNG 902 RPQ S+CF+ + DDSIE I+D K A + K G G + IR+ G+ G S+G Sbjct: 166 RPQCSACFIQSV-DDSIESIFDLAKTEAKLFKYGSGTGSNFSKIRSKYE-ATGSGGKSSG 223 Query: 903 IVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFA 1082 ++ L V + A + GG R+ A V ++ H ++ +F+D + +EE +A L A Sbjct: 224 LISFLEVLDKGAGAIKSGGTTRRAAKMVVVDIDHPEVLDFIDWKM---REEQKAHLLIAA 280 Query: 1083 ----------------------LWVPDLFMQRVQNNEDWSPFCPNEAPGLADCWGXXXXX 1196 + V D FM+ V+ W L + Sbjct: 281 GLSADFEGEAYRTVSGQNANNSVRVSDAFMKAVEQERPWKLKARLTGKVLRE-------- 332 Query: 1197 XXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLC 1376 IPA +W I +A P + + D+ N+ I SSN C Sbjct: 333 --------------IPAGEVWNRITRAAWMCADPGIQFHDTINKWHTCPETDIIHSSNPC 378 Query: 1377 TEIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVT 1556 +E + + + CNLASI L +F+ + G FDF+ Sbjct: 379 SEYMFL----DDSACNLASINLVKFLNDTGD-------------------FDFESFIHTA 415 Query: 1557 STVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRD 1736 T+ +++ + YP + +++ +RP+G+G L M G+ +DS E + Sbjct: 416 RTLFVAQEILVDYSSYPTQRVAQNSHDYRPLGLGFANLGSLLMRKGVAYDSDEGRAWAGA 475 Query: 1737 IFETIYYHXXXXXXXXXXXXGPYETYEGSPVS--------KGIIQPDMWNVVP-----ST 1877 + + GP+ Y + S + + W ++P + Sbjct: 476 LTSLMSGVAYLTSSEMARAKGPFAGYRKNSKSMLKVMKMHERALNQVAWKMLPAGIDKAV 535 Query: 1878 RWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILG-NNECFEPYTSNI-YSRRVLSGEFV 2051 R W + K G RN+ PT + ++ + EP S I + + V GE Sbjct: 536 RNLWKGVLYNGEKYGYRNAQATVIAPTGTIGLLMDCDTTGIEPDFSLIKFKKLVGGGEIQ 595 Query: 2052 VVNKHLLHDLTEMGIWTPALKN--KIIYEDGSIQKMEEI-PDDLKAIYKTVWEIKQKTL- 2219 +VN+ + L + + + K + E+ S+ ++ P+DL Q+ L Sbjct: 596 IVNQSVDAALASLQYFEDERQAILKYVEENNSVVGAPQMHPEDLPVFDTATAMPGQRVLS 655 Query: 2220 ----VDMAVDRGCYIDQSQSLNVHMDQPNFA---KLTSLHFHAWSKGLKTGMYY 2360 V M +I + S V+M P+ A ++ ++F AW G+K Y Sbjct: 656 PESHVKMMAAVQPFISGAISKTVNM--PSTATEEDISRIYFLAWKLGVKAVAVY 707
>O54196:NRDJ_STRCL Vitamin B12-dependent ribonucleotide reductase - Streptomyces| clavuligerus Length = 961 Score = 103 bits (258), Expect = 3e-21 Identities = 129/591 (21%), Positives = 226/591 (38%), Gaps = 31/591 (5%) Frame = +3 Query: 681 FTHASPTLFNAGTPRP-QLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIR 857 F+ SP FN GTP+P Q+S+CF++ + DDS+E I D KE +I K G G+++ IR Sbjct: 139 FSFNSPVWFNVGTPQPQQVSACFILSV-DDSMESILDWYKEEGMIFKGGSGAGLNLSRIR 197 Query: 858 ATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRK 1037 ++ + + G ++G V +R + +A + GG R+ A V L+ H DI F++ + Sbjct: 198 SSKELL-SSGGNASGPVSFMRGADASAGTIKSGGATRRAAKMVILDVDHPDIEGFIETKV 256 Query: 1038 NHGKEENRARDLFF--ALWVPDLFMQRVQNNEDWSPFCPNEAPGLADCWGXXXXXXXXXX 1211 ++ RD F L D+ + QN N + + D + Sbjct: 257 KEEEKIRALRDAGFDMDLGGDDITSVQYQN--------ANNSVRVNDEFMRAVESGSAFG 308 Query: 1212 XXXXXXXXVI---PAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTE 1382 +I A+ L+ + +A P + Y D+ NR G I SN C+E Sbjct: 309 LRARMTGEIIEQVDAKALFRKMAQAAWACADPGIQYDDTINRWHTCPESGRINGSNPCSE 368 Query: 1383 IIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTST 1562 + + CNLAS+ L +F+ + +G N+ FD ++ +V Sbjct: 369 YMHL----DNTSCNLASLNLMKFLTD---------------DGEGNQSFDVERFAKVVEL 409 Query: 1563 VTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIF 1742 V ++ I +P + + R +GIG L M G +DS + + I Sbjct: 410 VITAMDISICFADFPTQKIGENTRAFRQLGIGYANLGALLMATGHAYDSDGGRAIAGAIS 469 Query: 1743 ETIYYHXXXXXXXXXXXXGPYETY-----------------EGSPVSKGIIQPDMWNVVP 1871 + GPY+ Y + V + +W Sbjct: 470 SLMTGTSYRRSAELAAVVGPYDGYARNAAPHNQVMRQHADANDTAVRMDDLDTPIWAAAT 529 Query: 1872 STRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILG-NNECFEPYTSNI-YSRRVLSGE 2045 T W + K G RN+ PT + + + EP + + + + V G Sbjct: 530 ET---WQDVLRLGEKNGFRNAQASVIAPTGTIGLAMSCDTTGLEPDLALVKFKKLVGGGS 586 Query: 2046 FVVVNKHLLHDLTEMGIWTPALKNKI--IYEDGSIQKMEEIPDDLKAIYKTVW---EIKQ 2210 +VN + L +G ++ + I E G++ + + ++ I Sbjct: 587 MQIVNGTVPQALRRLGYQAEQIEAIVEHIAEHGNVLDAPGLKTEHYKVFDCAMGERSISA 646 Query: 2211 KTLVDMAVDRGCYIDQSQSLNVHM-DQPNFAKLTSLHFHAWSKGLKTGMYY 2360 V M +I + S V+M + ++ ++F AW G+K Y Sbjct: 647 MGHVRMMAAIQPWISGALSKTVNMPESATVEEVEEIYFEAWKMGVKALAIY 697
>O69981:NRDJ_STRCO Vitamin B12-dependent ribonucleotide reductase - Streptomyces| coelicolor Length = 967 Score = 102 bits (255), Expect = 7e-21 Identities = 96/384 (25%), Positives = 159/384 (41%), Gaps = 6/384 (1%) Frame = +3 Query: 681 FTHASPTLFNAGTPRP-QLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIR 857 F+ SP FN GTP+P Q+S+CF++ + DDS+E I D KE +I K G G+++ IR Sbjct: 139 FSFNSPVWFNVGTPQPQQVSACFILSV-DDSMESILDWYKEEGMIFKGGSGAGLNLSRIR 197 Query: 858 ATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRK 1037 ++ + + G ++G V +R + +A + GG R+ A V L+ H DI +F+ + Sbjct: 198 SSKELL-SSGGNASGPVSFMRGADASAGTIKSGGATRRAAKMVILDVDHPDIEDFIQTKV 256 Query: 1038 NHGKEENRARDLFF--ALWVPDLFMQRVQNNEDWSPFCPNEAPGLADCWGXXXXXXXXXX 1211 ++ RD F L D+ + QN N + + D + Sbjct: 257 KEEEKIRALRDAGFDMDLGGDDITSVQYQN--------ANNSVRVNDTFMKAVQDGGKFG 308 Query: 1212 XXXXXXXXVI---PAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTE 1382 VI A+ L+ + +A P + Y D+ N G I SN C+E Sbjct: 309 LTSRMTGEVIEEVDAKALFRKMAEAAWACADPGIQYDDTINAWHTCPESGRINGSNPCSE 368 Query: 1383 IIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTST 1562 + + CNLAS+ L +F+++ +G N+ FD ++ +V Sbjct: 369 YMHL----DNTSCNLASLNLMKFLKD---------------DGKGNQSFDAERFSKVVEL 409 Query: 1563 VTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIF 1742 V ++ I +P + + R +GIG L M G +DS + L I Sbjct: 410 VITAMDISICFADFPTQKIGENTRAFRQLGIGYANLGALLMATGHAYDSDGGRALAGAIT 469 Query: 1743 ETIYYHXXXXXXXXXXXXGPYETY 1814 + GPY+ Y Sbjct: 470 SLMTGTSYRRSAELAAIVGPYDGY 493
>Q82KE2:NRDJ_STRAW Vitamin B12-dependent ribonucleotide reductase - Streptomyces| avermitilis Length = 964 Score = 101 bits (251), Expect = 2e-20 Identities = 94/384 (24%), Positives = 160/384 (41%), Gaps = 6/384 (1%) Frame = +3 Query: 681 FTHASPTLFNAGTPRP-QLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIR 857 F+ SP FN GTP+P Q+S+CF++ + DDS+E I D KE +I K G G+++ IR Sbjct: 138 FSFNSPVWFNVGTPQPQQVSACFILAV-DDSMESILDWYKEEGMIFKGGSGAGLNLSRIR 196 Query: 858 ATGSYIRGTNGTSNGIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRK 1037 ++ + + G ++G V +R + +A + GG R+ A V L+ H DI +F++ + Sbjct: 197 SSKELL-SSGGNASGPVSFMRGADASAGTIKSGGATRRAAKMVILDVDHPDIEDFIETKV 255 Query: 1038 NHGKEENRARDLFF--ALWVPDLFMQRVQNNEDWSPFCPNEAPGLADCWGXXXXXXXXXX 1211 ++ RD F L D+ + QN N + + D + Sbjct: 256 KEEEKIRALRDAGFDMDLGGDDITSVQYQN--------ANNSVRVNDTFMKAVEEGGKFG 307 Query: 1212 XXXXXXXXVI---PAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTE 1382 VI A++L+ + +A P + Y D+ N G I SN C+E Sbjct: 308 LTSRMTGEVIEEVDAKSLFRKMAEAAWACADPGIQYDDTINHWHTCPESGRINGSNPCSE 367 Query: 1383 IIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTST 1562 + + CNLAS+ L +F+++ +G + F+ ++ +V Sbjct: 368 YMHL----DNTSCNLASLNLMKFLKD---------------DGKGRQSFEVERFAKVVEL 408 Query: 1563 VTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIF 1742 V ++ I +P + + R +GIG L M G +DS + L I Sbjct: 409 VITAMDISICFADFPTQKIGENTRAFRQLGIGYANLGALLMATGHAYDSDGGRALAGAIT 468 Query: 1743 ETIYYHXXXXXXXXXXXXGPYETY 1814 + GPY+ Y Sbjct: 469 SLMTGTSYKRSAELAAVVGPYDGY 492
>Q7UI46:NRDJ_RHOBA Vitamin B12-dependent ribonucleotide reductase - Rhodopirellula| baltica Length = 1040 Score = 97.8 bits (242), Expect = 2e-19 Identities = 127/591 (21%), Positives = 226/591 (38%), Gaps = 46/591 (7%) Frame = +3 Query: 726 PQLSSCFLICMKDDSIEGIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSNGI 905 PQ S+CF+ + DD++E I A++ K G G + IR+ + G GT +G Sbjct: 209 PQGSACFIQSV-DDNMEDIMRLACSEAMLFKFGSGTGTDLSTIRSQREKLSG-GGTPSGP 266 Query: 906 VPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLF--- 1076 + +RV++ A V GG R+ A L+ WH DI EF++ + EE +A L Sbjct: 267 LSFMRVYDSIAGVVKSGGKTRRAAKMQSLKVWHPDILEFIECK---WAEEKKAHALIREG 323 Query: 1077 -------------------FALWVPDLFMQRVQNNEDWSPFCPNEAPGLADCWGXXXXXX 1199 ++ + D +M+ V+ NE++ + P Sbjct: 324 YDSNFNGEAYASVCFQNANLSVRLTDDYMEAVRKNENFQTRWITDKP------------- 370 Query: 1200 XXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCT 1379 A+ L + + G P + Y + N+ N G I +SN C+ Sbjct: 371 -------TTEPPSYVAKELLNKMAECAWHCGDPGVQYDTTINKWHTCPNSGAINASNPCS 423 Query: 1380 EIIEFTSPEETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTS 1559 E + ++TA CNLASI L +FV++ G FD ++ Sbjct: 424 EYMFL---DDTA-CNLASINLMKFVQQDGS-------------------FDHERFRAACR 460 Query: 1560 TVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDI 1739 T +++ YP E R++ + RP+G+G L M G+P+DS A+ + + Sbjct: 461 TFFIAQEILVDHASYPTEPIARNSHKFRPLGLGYSNLGSVIMTAGLPYDSDAARGMCGSL 520 Query: 1740 FETIYYHXXXXXXXXXXXXGPYETY-EGSPVSKGIIQP-----DMWN------VVPSTRW 1883 ++ G ++ Y E ++Q D N + + R Sbjct: 521 TALLHGEANRTSAELASVVGTFDGYVENEAPMLRVMQMHRDACDQINDDGPAELKEAARE 580 Query: 1884 NWPTLRETIAKVGVRNSLLVAPMPTASTSQILG-NNECFEPYTSNI-YSRRVLSGEFVVV 2057 W + E K G RN+ PT + S ++ + EP + + Y + G +V Sbjct: 581 LWDGVLEIGEKYGFRNAQATVLAPTGTISFMMDCDTTGIEPDIALVKYKQLAGGGMLKIV 640 Query: 2058 NKHLLHDLTEMGIWTPALKNKIIYEDG--SIQKMEEIPDDLKAIYKTVWE-------IKQ 2210 N+ + L +G + + Y D +I+ + D+ A++ ++ I Sbjct: 641 NQTVKLGLKTLGYDADTIDEILKYVDANDTIEGAPGLQDEHLAVFDCAFKPANGVRSIGW 700 Query: 2211 KTLVDMAVDRGCYIDQSQSLNVHMDQPNFAK-LTSLHFHAWSKGLKTGMYY 2360 + + M ++ + S V+M + + +F W GLK Y Sbjct: 701 RAHITMMAAAQPFLSGAISKTVNMPTDVTPQDIADAYFWGWELGLKAIAIY 751
>P52343:RIR1_HHV6U Ribonucleoside-diphosphate reductase large chain - Human herpesvirus| 6A (strain Uganda-1102) (HHV-6 variant A) (Human B lymphotropic virus) Length = 804 Score = 63.5 bits (153), Expect = 4e-09 Identities = 62/244 (25%), Positives = 103/244 (42%), Gaps = 5/244 (2%) Frame = +3 Query: 1521 RYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMP 1700 ++F F++L V + N +I+ + R +GI V GL FM +G+ Sbjct: 469 KFFMFNELRRVVRKMVLVANAVIDYAVENKDFLCEGIEDGRSLGICVTGLHSVFMTVGLS 528 Query: 1701 FDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXG-PYETYEGSPVSKGIIQPDMWNVVPST 1877 + P+A++L R I E IYY P ++ S + G++ D ++ V T Sbjct: 529 YAHPDARRLYRMICEHIYYTCVRTSVDCCMKGAEPCNLFDRSKYALGMLYFDHFDNVECT 588 Query: 1878 --RWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRRVLSGEFV 2051 W TLR+ + GVRN A I+ ++E F P N RR S V Sbjct: 589 LPEELWTTLRKDVLMHGVRNIHFTAGTAMQKEFDIINSSESFWPMEDNKILRR--SNIKV 646 Query: 2052 VVNKHLLHDLTEMGIWTPALKNKII--YEDGSIQKMEEIPDDLKAIYKTVWEIKQKTLVD 2225 V+ K L+D+T +++ LK+ I Y + + + + LK + V + D Sbjct: 647 VIGKDGLNDVT--SVYSSELKSLYIPVYNNLLLNRFNKHQQYLKTVGYRVLNVDTNLFTD 704 Query: 2226 MAVD 2237 +D Sbjct: 705 KELD 708
>P50641:RIR1_HHV7J Ribonucleoside-diphosphate reductase large chain - Human herpesvirus| 7 (strain JI) (HHV-7) (Human T lymphotropic virus) Length = 806 Score = 60.1 bits (144), Expect = 5e-08 Identities = 80/366 (21%), Positives = 144/366 (39%), Gaps = 4/366 (1%) Frame = +3 Query: 945 VDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDLFFALWVPDLFMQRVQN- 1121 V++ K G +YLE WH + +LD + + F L +P++FM+R++ Sbjct: 289 VEKDTNKTTG-LTIYLEIWHLSLLMWLDFCEILPTTVQ----VKFCLILPEIFMERLKTE 343 Query: 1122 NEDWSPFCPNEAPGLADCWGXXXXXXXXXXXXXXXXXXVIPAQTLWFDILKAQIETGTPY 1301 N WS F A L + I +TL +I + + G Sbjct: 344 NSYWSVFHKALAINLG-LYDESDFTSKYLECERTAEHARIKTETLLDNICRC-LRRGQMG 401 Query: 1302 MLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETAVCNLASIALPRFVREKGVPIES 1481 +++ + ++ S + + N ++I F TA ++ L FV +S Sbjct: 402 FIFRKNIHKYSMLPQIASYCLGN-SMDVIPFEYGLNTAF--RIALNLSYFVENVSEEQKS 458 Query: 1482 HPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYYPVETARRSNMRHRPIGIGV 1661 H + +++ F+ K+ + + + N +I+ + + R + I V Sbjct: 459 HTN--IDMFHYRDKIFNLKKMRKTVTELVLIGNAVIDYALENRDFLMDGIVNARSLAICV 516 Query: 1662 QGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXG-PYETYEGSPVSKG 1838 GL M + +PF+S QL R + E IYY P ++ S ++G Sbjct: 517 TGLHSALMSMNLPFNSQLGCQLYRIVCENIYYSSVRTSMNCCKKGAEPCSFFQRSKYAQG 576 Query: 1839 IIQPDMWNVVPSTRWN--WPTLRETIAKVGVRNSLLVAPMPTASTSQILGNNECFEPYTS 2012 I+ D+++ V T N W LR I K G+RN V+ + +L ++ F P Sbjct: 577 ILHCDLYDNVEYTLPNVLWTNLRSDIKKYGLRNLTFVSGSAMSKEFDLLNCSQSFCPIEG 636 Query: 2013 NIYSRR 2030 N +R Sbjct: 637 NKILKR 642
>Q8F3P1:NRDJ_LEPIN Vitamin B12-dependent ribonucleotide reductase - Leptospira| interrogans Length = 1209 Score = 50.4 bits (119), Expect = 4e-05 Identities = 33/111 (29%), Positives = 53/111 (47%), Gaps = 2/111 (1%) Frame = +3 Query: 726 PQLSSCFLICMKDDSIE--GIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSN 899 PQ +CF+ + DD + GI D A + K G G + N+R + G G S+ Sbjct: 202 PQPHACFIQSVDDDLVNEGGIMDLWVREARLFKYGSGTGTNFSNLRGENEPLSG-GGKSS 260 Query: 900 GIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKE 1052 G++ L++ + A + GG R+ A V L+ H DI F+D + K+ Sbjct: 261 GLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDVDHPDIENFIDWKVTEEKK 311 Score = 49.7 bits (117), Expect = 7e-05 Identities = 43/190 (22%), Positives = 70/190 (36%) Frame = +3 Query: 1245 AQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETAVCN 1424 A+ LW I A + P Y + N G I +SN C+E + + CN Sbjct: 449 ARELWEKISYAAWASADPGTQYHTTINEWHTCPEDGPINASNPCSEYMFL----DNTACN 504 Query: 1425 LASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYY 1604 LAS L +FV + + FD + + T L + M + Sbjct: 505 LASANLQKFVNLETLN------------------FDVEGFRYLCKLWTIILEISVTMAQF 546 Query: 1605 PVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXX 1784 P + + + R +G+G L M+LG+P+DS +A + I ++ Sbjct: 547 PSKEIAELSYKFRTLGLGYANLGSVLMVLGIPYDSQQAMAITGAISSIMHMTAYATSAEM 606 Query: 1785 XXXXGPYETY 1814 GP+ Y Sbjct: 607 AKEQGPFVGY 616
>Q72S00:NRDJ_LEPIC Vitamin B12-dependent ribonucleotide reductase - Leptospira| interrogans serogroup Icterohaemorrhagiae serovar copenhageni Length = 1209 Score = 50.4 bits (119), Expect = 4e-05 Identities = 33/111 (29%), Positives = 53/111 (47%), Gaps = 2/111 (1%) Frame = +3 Query: 726 PQLSSCFLICMKDDSIE--GIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSN 899 PQ +CF+ + DD + GI D A + K G G + N+R + G G S+ Sbjct: 202 PQPHACFIQSVDDDLVNEGGIMDLWVREARLFKYGSGTGTNFSNLRGENEPLSG-GGKSS 260 Query: 900 GIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKE 1052 G++ L++ + A + GG R+ A V L+ H DI F+D + K+ Sbjct: 261 GLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDVDHPDIENFIDWKVTEEKK 311 Score = 49.7 bits (117), Expect = 7e-05 Identities = 43/190 (22%), Positives = 70/190 (36%) Frame = +3 Query: 1245 AQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETAVCN 1424 A+ LW I A + P Y + N G I +SN C+E + + CN Sbjct: 449 ARELWEKISYAAWASADPGTQYHTTINEWHTCPEDGPINASNPCSEYMFL----DNTACN 504 Query: 1425 LASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMNYY 1604 LAS L +FV + + FD + + T L + M + Sbjct: 505 LASANLQKFVNLETLN------------------FDVEGFRYLCKLWTIILEISVTMAQF 546 Query: 1605 PVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXX 1784 P + + + R +G+G L M+LG+P+DS +A + I ++ Sbjct: 547 PSKEIAELSYKFRTLGLGYANLGSVLMVLGIPYDSQQAMAITGAISSIMHMTAYATSAEM 606 Query: 1785 XXXXGPYETY 1814 GP+ Y Sbjct: 607 AKEQGPFVGY 616
>Q8UEM4:NRDJ_AGRT5 Vitamin B12-dependent ribonucleotide reductase - Agrobacterium| tumefaciens (strain C58 / ATCC 33970) Length = 1272 Score = 48.9 bits (115), Expect = 1e-04 Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 2/107 (1%) Frame = +3 Query: 726 PQLSSCFLICMKDDSIE--GIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSN 899 PQ +CF+ ++DD + GI D A + K G G + +R G + G G S+ Sbjct: 194 PQPHACFIQSVEDDLVNEGGIMDLWVREARLFKYGSGTGSNFSYLRGEGEKLSG-GGKSS 252 Query: 900 GIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKN 1040 G++ L++ + A + GG R+ A V ++ H DI ++D + N Sbjct: 253 GLMSFLKIGDRAAGAIKSGGTTRRAAKMVVVDADHPDIEAYIDWKVN 299 Score = 43.5 bits (101), Expect = 0.005 Identities = 37/163 (22%), Positives = 64/163 (39%) Frame = +3 Query: 1239 IPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETAV 1418 + A+ LW I A + P + + + N G I++SN C+E + ++TA Sbjct: 431 LKARDLWEKISHAAWASADPGLHFNTTMNDWHTSPAEGPIRASNPCSEYMFL---DDTA- 486 Query: 1419 CNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMN 1598 CNLAS+ L +F +K + D T L + M Sbjct: 487 CNLASLNLLQF------------------KDAKTKRIDIADYEHAVRLWTVVLEVSVMMA 528 Query: 1599 YYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQL 1727 +P + +R +G+G + M G+P+DS E + + Sbjct: 529 QFPSRQIAERSYEYRTLGLGYANIGGLLMSSGIPYDSDEGRAI 571
>Q89MB9:NRDJ_BRAJA Vitamin B12-dependent ribonucleotide reductase - Bradyrhizobium| japonicum Length = 1254 Score = 46.6 bits (109), Expect = 6e-04 Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Frame = +3 Query: 726 PQLSSCFLICMKDDSIE--GIYDTLKECAVISKSAGGIGVSVHNIRATGSYIRGTNGTSN 899 PQ +CF+ + DD + GI D A + K G G + +R G + G G S+ Sbjct: 194 PQPHACFIQGVGDDLVNEGGIMDLWVREARLFKYGSGTGSNFSRLRGEGEKLSG-GGRSS 252 Query: 900 GIVPMLRVFNDTARYVDQGGGKRKGAFAVYLEPWHADIFEFLDLRKNHGKEENRARDL 1073 G++ L++ + A + GG R+ A V ++ H DI ++D + KEE + L Sbjct: 253 GLMSFLKIGDRAAGAIKSGGTTRRAAKMVVVDVDHPDIETYIDWKV---KEEQKVAAL 307 Score = 43.5 bits (101), Expect = 0.005 Identities = 38/163 (23%), Positives = 66/163 (40%) Frame = +3 Query: 1239 IPAQTLWFDILKAQIETGTPYMLYKDSCNRKSNQQNLGTIKSSNLCTEIIEFTSPEETAV 1418 + A+ LW I A + P + + + N + G I++SN C+E + ++TA Sbjct: 431 LKARDLWEKIGYAAWASADPGLHFNTTMNDWHTCKASGDIRASNPCSEYMFL---DDTA- 486 Query: 1419 CNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKIIEMN 1598 CNLAS L F ++FD + + T L + M Sbjct: 487 CNLASANLLTFYNVA------------------TKHFDVEGYEHLCRLWTVVLEISVMMA 528 Query: 1599 YYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQL 1727 +P + + R +G+G + M +G+P+DS E + L Sbjct: 529 QFPSKAIAELSYEFRTLGLGYANIGGLLMTMGLPYDSKEGRAL 571
>Q9XD73:NRDJ_STRCT Vitamin B12-dependent ribonucleotide reductase - Streptomyces| cattleya Length = 599 Score = 40.0 bits (92), Expect = 0.053 Identities = 33/136 (24%), Positives = 54/136 (39%) Frame = +3 Query: 1407 ETAVCNLASIALPRFVREKGVPIESHPSKLAGSNGSKNRYFDFDKLGEVTSTVTFNLNKI 1586 + + CNLAS+ L +F+R+ ++ +G+ G N D ++ +V V ++ Sbjct: 4 DNSSCNLASLNLMKFLRD-----DTASDGASGAGG--NMSLDAERFAKVVELVITAMDIS 56 Query: 1587 IEMNYYPVETARRSNMRHRPIGIGVQGLADTFMLLGMPFDSPEAQQLNRDIFETIYYHXX 1766 I +P E + R +GIG L M G +DS + L I + Sbjct: 57 ICFADFPTEKIGETTRAFRQLGIGYANLGALLMATGHAYDSDGGRALAGAITSLMTGTSY 116 Query: 1767 XXXXXXXXXXGPYETY 1814 GPYE Y Sbjct: 117 RRSAELAAVVGPYEGY 132
>P16782:RIR1_HCMVA Ribonucleoside-diphosphate reductase large chain - Human| cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) Length = 906 Score = 38.9 bits (89), Expect = 0.12 Identities = 44/167 (26%), Positives = 73/167 (43%), Gaps = 9/167 (5%) Frame = +3 Query: 1509 GSKNRYFDFDKLGE-VTSTVTFN---LNKIIEMNYYPVETARRSNMRHRPIGIGVQGLAD 1676 G+ RYFD L E VT V + L+ ++ + + VE+A + RP+ IGV GL Sbjct: 623 GNTRRYFDLSVLRELVTEAVVWGNARLDALMSASEWWVESALE---KLRPLHIGVAGLHT 679 Query: 1677 TFMLLGMPFDSPEAQQLNRDIFETIYYHXXXXXXXXXXXXGP-YETYEGSPVSKGIIQPD 1853 M LG + + + L IFE +Y+ P E +E + +G + Sbjct: 680 ALMRLGFTYFA--SWDLIERIFEHMYFAAVRASVDLCKSGLPRCEWFERTIYQEGKFIFE 737 Query: 1854 MWNV----VPSTRWNWPTLRETIAKVGVRNSLLVAPMPTASTSQILG 1982 ++ + + S RW LR + + G+RN +A P + + G Sbjct: 738 LYRLPRLSIASARWE--ALRADMLEFGLRNCQFLAVGPDDEVAHLWG 782
>Q58242:Y832_METJA Uncharacterized protein MJ0832 [Contains: Mja rnr-1 intein; Mja| rnr-2 intein] - Methanococcus jannaschii Length = 1750 Score = 37.7 bits (86), Expect = 0.26 Identities = 20/57 (35%), Positives = 34/57 (59%) Frame = +3 Query: 87 KMYVVKRDGRTETVHFDKITARLKKLSYGLSQEHCDPVLVAQKVCAGVYKGVTTSQL 257 + YV+KRD R E + +K+ L ++ G++ D ++ +VCA VY G+TT +L Sbjct: 13 EFYVIKRDKRKEKFNVNKLAKSL--INSGVNYGDLDTII--SEVCAKVYNGITTDEL 65
>Q821Z7:GLMS_CHLCV Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] -| Chlamydophila caviae Length = 609 Score = 33.5 bits (75), Expect = 5.0 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 8/94 (8%) Frame = +3 Query: 570 GVVVERPQHMLMRVSVG--------IHKDDIDSAIRTYHLMSQRWFTHASPTLFNAGTPR 725 G+ P+ + +R +VG + K+++ S++ H RW TH PT+ NA Sbjct: 33 GLAAVIPERLFVRKTVGRVDELRSSLEKENVPSSLAIGHT---RWATHGVPTVKNAHPHV 89 Query: 726 PQLSSCFLICMKDDSIEGIYDTLKECAVISKSAG 827 + S+C ++ GI D KE + S G Sbjct: 90 DENSACAIV------HNGIIDNFKELRSLLISEG 117 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 452,562,589 Number of extensions: 9630864 Number of successful extensions: 25964 Number of sequences better than 10.0: 70 Number of HSP's gapped: 25676 Number of HSP's successfully gapped: 97 Length of query: 937 Length of database: 100,686,439 Length adjustment: 123 Effective length of query: 814 Effective length of database: 66,948,154 Effective search space: 54495797356 Effective search space used: 54495797356 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
