ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf21m03 |
|---|---|
| Clone Library Name | barley_pub |
>Q05047:C72A1_CATRO Cytochrome P450 72A1 - Catharanthus roseus (Rosy periwinkle)| (Madagascar periwinkle) Length = 524 Score = 481 bits (1238), Expect = e-135 Identities = 234/491 (47%), Positives = 328/491 (66%), Gaps = 5/491 (1%) Frame = +3 Query: 186 TPRRLGRALRAQGIGGTRYRLFTGDIPENSRFNAEARSQPMPPGSHHIAPRVLPMFTNAI 365 TP+R+ + LR QG G YR GD+ E+ + + EA S+PM ++ I PR++P + I Sbjct: 34 TPKRIEKRLRQQGFRGNPYRFLVGDVKESGKMHQEALSKPME-FNNDIVPRLMPHINHTI 92 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTR--IGRLLANGLANHEGE 539 +G+ SFTW G PR+ V +PEL++E+L++ + K + + L G+ + EG Sbjct: 93 NTYGRNSFTWMGRIPRIHVMEPELIKEVLTHS-SKYQKNFDVHNPLVKFLLTGVGSFEGA 151 Query: 540 KWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGD 719 KW+KHRRI++PAF EK+K MLP F+ C +M+T+WE QG EVD+ P F LT D Sbjct: 152 KWSKHRRIISPAFTLEKLKSMLPAFAICYHDMLTKWEKIAEKQGSHEVDIFPTFDVLTSD 211 Query: 720 VISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRM 899 VIS+ AFGS ++EG KIF+L EL + I + ++IPG+ + PTK N+RM+ I++EI Sbjct: 212 VISKVAFGSTYEEGGKIFRLLKELMDLTIDCMRDVYIPGWSYLPTKRNKRMKEINKEITD 271 Query: 900 ILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANL---GLSIEDIIQECKLFYF 1070 +LR II K+ +A+K SN+Q+ + N G+SI D+I+ECKLFYF Sbjct: 272 MLRFIINKRMKALKAGEPGEDDLLGVLLESNIQEIQKQGNKKDGGMSINDVIEECKLFYF 331 Query: 1071 AGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIFYEVLR 1250 AG ETT VLLTWT I+LS HPEWQE+AREEVL FG+ P+FE L+ LK V+MI YEVLR Sbjct: 332 AGQETTGVLLTWTTILLSKHPEWQERAREEVLQAFGKNKPEFERLNHLKYVSMILYEVLR 391 Query: 1251 LYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGIS 1430 LYPP+ LT+ +K +LG PAG +MLP + +H + IWG+DA EFNP RF DG++ Sbjct: 392 LYPPVIDLTKIVHKDTKLGSYTIPAGTQVMLPTVMLHREKSIWGEDAMEFNPMRFVDGVA 451 Query: 1431 NAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQP 1610 NA K + PF GPR+C+GQNFAL +AK+ L+ ILQRF F+++PSY+HAP+T++T+QP Sbjct: 452 NATKNNVTYLPFSWGPRVCLGQNFALLQAKLGLAMILQRFKFDVAPSYVHAPFTILTVQP 511 Query: 1611 QHGAQIRLKKI 1643 Q G+ + KK+ Sbjct: 512 QFGSHVIYKKL 522
>O23365:C97B3_ARATH Cytochrome P450 97B3 - Arabidopsis thaliana (Mouse-ear cress)| Length = 580 Score = 173 bits (439), Expect = 2e-42 Identities = 137/474 (28%), Positives = 223/474 (47%), Gaps = 50/474 (10%) Frame = +3 Query: 369 EHGKVSFTWFGPTPRVMVPDPELVREIL-SNKFGHFGKQRSTRIGRLLANGLANHEGEKW 545 EHG + FGP V++ DP + R +L N F + + + ++ GL + + W Sbjct: 109 EHGGIYKLAFGPKAFVVISDPIIARHVLRENAFSYDKGVLAEILEPIMGKGLIPADLDTW 168 Query: 546 AKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWEN------SMSAQGLCEVDVCPEFQN 707 RR + PAFH ++ M+ VFS C E+MI + E + S + E+D+ EF + Sbjct: 169 KLRRRAITPAFHKLYLEAMVKVFSDCSEKMILKSEKLIREKETSSGEDTIELDLEAEFSS 228 Query: 708 LTGDVISRTAFGSNF----QEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKN--NRR 869 L D+I + F +F +E I + G L E + T + P YW FP R Sbjct: 229 LALDIIGLSVFNYDFGSVTKESPVIKAVYGTLFEA--EHRSTFYFP-YWNFPPARWIVPR 285 Query: 870 MRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANL----GLSIE 1037 R ++++I + G + A + +N++ ++ L G+ I+ Sbjct: 286 QRKFQSDLKIINDCLDGLIQNAKETRQETDVEKLQERDYTNLKDASLLRFLVDMRGVDID 345 Query: 1038 D--IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSR 1211 D + + AG ETT+ +LTW + +LS +PE KA+ E+ G+ P +ES+ + Sbjct: 346 DRQLRDDLMTMLIAGHETTAAVLTWAVFLLSQNPEKIRKAQAEIDAVLGQGPPTYESMKK 405 Query: 1212 LKIVTMIFYEVLRLYPPITFLTRRTYKAM--------ELGGIKYPAGVNLMLPILFIHHD 1367 L+ + +I EVLRL+P L RRT K E G K P G ++ + + +H Sbjct: 406 LEYIRLIVVEVLRLFPQPPLLIRRTLKPETLPGGHKGEKEGHKVPKGTDIFISVYNLHRS 465 Query: 1368 PDIWGKDAREFNPERF-----ADGIS-----NAAKRPA-----------AFFPFGGGPRI 1484 P W + +F PERF ++GI + ++ P AF PFGGGPR Sbjct: 466 PYFW-DNPHDFEPERFLRTKESNGIEGWAGFDPSRSPGALYPNEIIADFAFLPFGGGPRK 524 Query: 1485 CIGQNFALQEAKMALSTILQRFSFEL--SPSYIHAPYTVITLQPQHGAQIRLKK 1640 CIG FAL E+ +AL+ + Q+F EL +P + + T+ ++G +LK+ Sbjct: 525 CIGDQFALMESTVALAMLFQKFDVELRGTPESVEL-VSGATIHAKNGMWCKLKR 577
>O48921:C97B2_SOYBN Cytochrome P450 97B2 - Glycine max (Soybean)| Length = 576 Score = 171 bits (434), Expect = 7e-42 Identities = 138/473 (29%), Positives = 215/473 (45%), Gaps = 49/473 (10%) Frame = +3 Query: 369 EHGKVSFTWFGPTPRVMVPDPELVREIL-SNKFGHFGKQRSTRIGRLLANGLANHEGEKW 545 EHG V FGP V+V DP + R IL N F + + + ++ GL + + W Sbjct: 104 EHGAVYKLAFGPKAFVVVSDPIVARHILRENAFSYDKGVLADILEPIMGKGLIPADLDTW 163 Query: 546 AKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGL-----CEVDVCPEFQNL 710 + RR++ PAFH+ ++ M+ +F+ C E I ++ + +G E+D+ EF +L Sbjct: 164 KQRRRVIAPAFHNSYLEAMVKIFTTCSERTILKFNKLLEGEGYDGPDSIELDLEAEFSSL 223 Query: 711 TGDVISRTAFGSNF----QEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKN--NRRM 872 D+I F +F +E I + G L E + T +IP YW P R Sbjct: 224 ALDIIGLGVFNYDFGSVTKESPVIKAVYGTLFEA--EHRSTFYIP-YWKIPLARWIVPRQ 280 Query: 873 RAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANL----GLSIED 1040 R ++++I + G A ++ N++ ++ L G ++D Sbjct: 281 RKFQDDLKVINTCLDGLIRNAKESRQETDVEKLQQRDYLNLKDASLLRFLVDMRGADVDD 340 Query: 1041 --IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRL 1214 + + AG ETT+ +LTW + +L+ +P +KA+ EV G P FESL L Sbjct: 341 RQLRDDLMTMLIAGHETTAAVLTWAVFLLAQNPSKMKKAQAEVDLVLGTGRPTFESLKEL 400 Query: 1215 KIVTMIFYEVLRLYPPITFLTRRTYKA--------MELGGIKYPAGVNLMLPILFIHHDP 1370 + + +I E LRLYP L RR+ K+ E G PAG ++ + + +H P Sbjct: 401 QYIRLIVVEALRLYPQPPLLIRRSLKSDVLPGGHKGEKDGYAIPAGTDVFISVYNLHRSP 460 Query: 1371 DIWGKDAREFNPERFADGISN------AAKRPA---------------AFFPFGGGPRIC 1487 W + +F PERF N A P+ AF PFGGGPR C Sbjct: 461 YFWDR-PDDFEPERFLVQNKNEEIEGWAGLDPSRSPGALYPNEVISDFAFLPFGGGPRKC 519 Query: 1488 IGQNFALQEAKMALSTILQRFSFEL--SPSYIHAPYTVITLQPQHGAQIRLKK 1640 +G FAL E+ +AL+ +LQ F EL +P + T T+ ++G RLKK Sbjct: 520 VGDQFALMESTVALTMLLQNFDVELKGTPESVEL-VTGATIHTKNGMWCRLKK 571
>P51870:CP4F5_RAT Cytochrome P450 4F5 - Rattus norvegicus (Rat)| Length = 526 Score = 165 bits (417), Expect = 7e-40 Identities = 124/413 (30%), Positives = 194/413 (46%), Gaps = 23/413 (5%) Frame = +3 Query: 381 VSFTWFGPT-PRVMVPDPELVREILSNKFGHFGKQRSTRIGRLL----ANGLANHEGEKW 545 + W GP P + + DP V +L + T R L +GL G+KW Sbjct: 87 IHLCWLGPVIPVLRLVDPAFVAPLLQAPA--LVAPKDTTFLRFLKPWLGDGLFLSSGDKW 144 Query: 546 AKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVI 725 ++HRR+L PAFH + +K + +F+ M +W++ + +G +++ +T D + Sbjct: 145 SRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAKWKH-LCLEGSARLEMFENISLMTLDSL 203 Query: 726 SRTAFG--SNFQEG-MKIFQLQGELSERLIQAFQTLFIP-GYWFFPTKNNRRMRAIDREI 893 + FG SN QE + ELS +I+ Q LF+ + ++ T + RR R + Sbjct: 204 QKCLFGFDSNCQESPSEYISAILELSSLIIKRSQQLFLYLDFLYYRTADGRRFRKACDLV 263 Query: 894 RMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNM----------QQSNGKANLGLSIEDI 1043 +I ++ R + + S + +GK LS EDI Sbjct: 264 HNFTDAVIRERRRLLSSQGTDEFLESKTKSKSKTLDFIDVLLLAKDEHGKE---LSDEDI 320 Query: 1044 IQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP---DFESLSRL 1214 E F F G +TT+ L+W L L+ HPE+QE+ R+EV P +++ L++L Sbjct: 321 RAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVWELLRDREPEEIEWDDLAQL 380 Query: 1215 KIVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDA 1391 +TM E LRL+PP L RR + + L G P G ++ I IHH+P +W D Sbjct: 381 PFLTMCIKESLRLHPPAIDLLRRCTQDIVLPDGRVIPKGNICVISIFGIHHNPSVW-PDP 439 Query: 1392 REFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 F+P RF D + + P +F PF GPR CIGQ FA+ E K+ ++ L RF Sbjct: 440 EVFDPFRF-DSENRQKRSPLSFIPFSAGPRNCIGQTFAMNEMKVVVALTLLRF 491
>P51869:CP4F4_RAT Cytochrome P450 4F4 - Rattus norvegicus (Rat)| Length = 522 Score = 165 bits (417), Expect = 7e-40 Identities = 127/422 (30%), Positives = 204/422 (48%), Gaps = 19/422 (4%) Frame = +3 Query: 342 LPMFTNAIKEHGKVSFTWFGPT-PRVMVPDPELVREILSNKFGHFGKQRS--TRIGRLLA 512 L T + + + TW GP P + + P+++R +LS K+ + + L Sbjct: 74 LKQVTKLVATYPQGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFLKPWLG 133 Query: 513 NGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVC 692 +GL +G+KW+ HRR+L PAFH +K + +F+ M +W++ +++ G +D+ Sbjct: 134 DGLLLSDGDKWSCHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQD-LASGGSARLDMF 192 Query: 693 PEFQNLTGDVISRTAFG--SNFQEG-MKIFQLQGELSERLIQAFQTLFIPGYWFFP-TKN 860 +T D + + F SN QE + ELS + + +Q L + + T N Sbjct: 193 KNISLMTLDSLQKCVFSFDSNCQEKPSEYISAILELSALVAKRYQQLLLHTDSLYQLTHN 252 Query: 861 NRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSN--------MQQSNGKA 1016 RR + + +I + RA+ + + + +GK Sbjct: 253 GRRFHKACKLVHNFTDAVIQGRRRALPSQHEDDILKAKARSKTLDFIDVLLLTKDEDGKE 312 Query: 1017 NLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV---LHYFGRTT 1187 LS EDI E F F G +TT+ L+W L L+ HPE+QE+ R+EV L T Sbjct: 313 ---LSDEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDRESTE 369 Query: 1188 PDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHH 1364 +++ L++L +TM E LRL+PP+T ++RR + + L G P GV ++ I HH Sbjct: 370 IEWDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHH 429 Query: 1365 DPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQ 1544 +P +W D ++P RF D + + P AF PF GPR CIGQ FA+ E K+AL+ L Sbjct: 430 NPTVW-PDPEVYDPFRF-DPENIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLL 487 Query: 1545 RF 1550 RF Sbjct: 488 RF 489
>Q8K4D6:CP4X1_RAT Cytochrome P450 4X1 - Rattus norvegicus (Rat)| Length = 507 Score = 164 bits (416), Expect = 9e-40 Identities = 125/447 (27%), Positives = 211/447 (47%), Gaps = 17/447 (3%) Frame = +3 Query: 363 IKEHGKVSFTWFGPTPRVM-VPDPELVREILSN---KFGHFGKQRSTRIGRLLANGLANH 530 +KE+ W GP + DP+ + LS K + + + +GR GL N Sbjct: 73 VKEYPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKTQYLHQLMTPFLGR----GLLNL 128 Query: 531 EGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNL 710 +G +W +HR +L PAFH + +K + + + M+ +WE + + Q ++V + Sbjct: 129 DGPRWFQHRCLLTPAFHQDILKPCVDMMAHSVNMMLDKWEKTWTTQETT-IEVFEHINLM 187 Query: 711 TGDVISRTAFGSN--------FQEGMKI-FQLQGELSERLIQAFQTLFIPGYWFFPTKNN 863 T D+I + AFG ++ +K F+L +S RL + I F + Sbjct: 188 TLDIIMKCAFGQETNCQINGTYESYVKATFELGEIISSRLYNFWHHHDII---FKLSPKG 244 Query: 864 RRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDI 1043 + + + I II +++ +K+ + + S D+ Sbjct: 245 HCFQELGKVIHQCTEKIIQDRKKTLKDQVNQDDTQTSQNFLDIVLSAQAGDEKAFSDADL 304 Query: 1044 IQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKI 1220 E F +AG + ++ ++W L L+++PE Q++ R E+ G ++ +E L + Sbjct: 305 RSEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGDGSSITWEQLDEIPY 364 Query: 1221 VTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDARE 1397 TM E LRL PPI ++R K + L G PAG+ ++L I +HH+P +W KD + Sbjct: 365 TTMCIKETLRLIPPIPSISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVW-KDPKV 423 Query: 1398 FNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF--SFELSPS 1571 F+P RF S + P AF PF GPR CIGQ FA+ E K+A++ L RF + +L+ Sbjct: 424 FDPLRFTKENSEQ-RHPCAFLPFSSGPRNCIGQQFAMLELKVAIALTLLRFRVAADLTRP 482 Query: 1572 YIHAPYTVITLQPQHGAQIRLKKI*AC 1652 + +TV L+P+HG + LKK+ C Sbjct: 483 PAFSSHTV--LRPKHGIYLHLKKLPEC 507
>P51871:CP4F6_RAT Cytochrome P450 4F6 - Rattus norvegicus (Rat)| Length = 537 Score = 164 bits (416), Expect = 9e-40 Identities = 125/414 (30%), Positives = 196/414 (47%), Gaps = 24/414 (5%) Frame = +3 Query: 381 VSFTWFGPT-PRVMVPDPELVREILSNKFGHFGKQRSTRIGRL---LANGLANHEGEKWA 548 + +W GP P + + P ++ +L K+ T G L L +GL GEKW Sbjct: 87 IHLSWVGPVYPILRLVHPNVIAPLLQASAAVAPKEM-TLYGFLKPWLGDGLLMSAGEKWN 145 Query: 549 KHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVIS 728 HRR+L PAFH + +K + +F+ M +W+ ++A+G +D+ +T D + Sbjct: 146 HHRRLLTPAFHFDILKSYVKIFNKSVNTMHAKWQR-LTAKGSARLDMFEHISLMTLDSLQ 204 Query: 729 RT--AFGSNFQEGMK-----IFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDR 887 + +F SN QE I +L + +R Q F L + ++ T + RR R Sbjct: 205 KCIFSFDSNCQESNSEYIAAILELSSLIVKRQRQPFLYL---DFLYYLTADGRRFRKACD 261 Query: 888 EIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNM---------QQSNGKANLGLSIED 1040 + +I ++ R+ N + + +GK GLS D Sbjct: 262 VVHNFTDAVI-RERRSTLNTQGVDEFLKARAKTKTLDFIDVLLLAKDEHGK---GLSDVD 317 Query: 1041 IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP---DFESLSR 1211 I E F F G +TT+ L+W L L+ HPE+QE+ R+EV P +++ L++ Sbjct: 318 IRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQ 377 Query: 1212 LKIVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKD 1388 L +TM E LRL+PP+ ++R + + L G P G ++ I +HH+P +W D Sbjct: 378 LPFLTMCIKESLRLHPPVLLISRCCSQDIVLPDGRVIPKGNICVISIFGVHHNPSVW-PD 436 Query: 1389 AREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 +NP RF D + + P AF PF GPR CIGQ FA+ E K+AL+ L RF Sbjct: 437 PEVYNPFRF-DPENPQKRSPLAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRF 489
>P79401:CP3AT_PIG Cytochrome P450 3A29 - Sus scrofa (Pig)| Length = 503 Score = 163 bits (413), Expect = 2e-39 Identities = 125/435 (28%), Positives = 204/435 (46%), Gaps = 26/435 (5%) Frame = +3 Query: 333 PRVLPMFTNAI--------------KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FG 467 PR LP F N + +++GK+ + G P + V DP +++ +L + + Sbjct: 41 PRPLPYFGNILGYRKGVDHFDKKCFQQYGKMWGVYDGRQPLLAVTDPNMIKSVLVKECYS 100 Query: 468 HFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRW 647 F +RS + N L+ E E+W + R +L+P F K+K M P+ S + +++ Sbjct: 101 VFTNRRSFGPLGAMRNALSLAEDEEWKRIRTLLSPTFTSGKLKEMFPIISHYGDLLVSNL 160 Query: 648 ENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQ-AFQTL 824 A+ V + F + DVI+ TAFG N E S++L++ +F Sbjct: 161 RKE--AEKGKPVTMKDIFGAYSMDVITSTAFGVNIDSLNNPQDPFVENSKKLLKFSFFDP 218 Query: 825 FIPGYWFFPTKNNRRMRAIDREIRMILR-----GIIGKKERAIKNXXXXXXXXXXXXXXS 989 F+ FFP + I + + L K + +K Sbjct: 219 FLLSLIFFPF-----LTPIFEVLNITLFPKSSVNFFTKSVKRMKESRLTDQQKRRVDLLQ 273 Query: 990 NMQQSNGKANL----GLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKARE 1157 M S + LS E+++ + +F FAG ETTS L+ L+ HP+ Q+K +E Sbjct: 274 LMINSQNSKEMDPHKSLSNEELVAQGIIFIFAGYETTSSALSLLAYELATHPDVQQKLQE 333 Query: 1158 EVLHYF-GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVN 1334 E+ F + P +++L++++ + M+ E LRLYP L R K +E+ G+ P G Sbjct: 334 EIEATFPNKAPPTYDALAQMEYLDMVVNETLRLYPIAARLERACKKDVEIHGVFVPKGTV 393 Query: 1335 LMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQE 1514 +++P+ +H DPD+W + EF PERF+ + P + PFG GPR CIG FAL Sbjct: 394 VVVPVFVLHRDPDLW-PEPEEFRPERFSKKHKDTI-NPYTYLPFGTGPRNCIGMRFALMN 451 Query: 1515 AKMALSTILQRFSFE 1559 K+AL +LQ FSF+ Sbjct: 452 MKLALVRVLQNFSFK 466
>Q9HCS2:CP4FC_HUMAN Cytochrome P450 4F12 - Homo sapiens (Human)| Length = 524 Score = 162 bits (411), Expect = 3e-39 Identities = 116/408 (28%), Positives = 198/408 (48%), Gaps = 20/408 (4%) Frame = +3 Query: 393 WFGPT-PRVMVPDPELVREILSNKFGHFGKQRSTRIGRL---LANGLANHEGEKWAKHRR 560 W GP P +++ P+ +R I +N + + I L L G+ G+KW++HRR Sbjct: 91 WLGPIIPFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRR 149 Query: 561 ILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRT-- 734 +L PAFH +K + +F+ M+ +W++ ++++G +D+ +T D + + Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQH-LASEGSSRLDMFEHISLMTLDSLQKCIF 208 Query: 735 AFGSNFQEGMK-----IFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRM 899 +F S+ QE I +L + +R Q + + ++ + + RR R + Sbjct: 209 SFDSHCQERPSEYIATILELSALVEKRSQHILQHM---DFLYYLSHDGRRFHRACRLVHD 265 Query: 900 ILRGIIGKKERA-----IKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLF 1064 +I ++ R I + + S + LS EDI E F Sbjct: 266 FTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTF 325 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP---DFESLSRLKIVTMIF 1235 F G +TT+ L+W L L+ HPE+QE+ R+EV P +++ L++L +TM Sbjct: 326 MFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCV 385 Query: 1236 YEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 E LRL+PP F++R + + L G P G+ ++ I+ +HH+P +W D ++P R Sbjct: 386 KESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVW-PDPEVYDPFR 444 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 F D ++ + P AF PF GPR CIGQ FA+ E K+ L+ +L F F Sbjct: 445 F-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491
>Q27515:C13A6_CAEEL Putative cytochrome P450 CYP13A6 - Caenorhabditis elegans| Length = 518 Score = 162 bits (410), Expect = 4e-39 Identities = 113/433 (26%), Positives = 200/433 (46%), Gaps = 36/433 (8%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF-GKQRSTRIGRLLANGLAN---HE 533 K++G V GP +++ +PE+V EI +F +F G++ IG + N + Sbjct: 60 KQYGPVYGFTEGPQQTMIISEPEMVNEIFKKQFDNFYGRKLRPIIGDPEKDKRVNIFSTQ 119 Query: 534 GEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLT 713 G++W + R + +P+F + ++++ C E++ W + ++D+ +Q T Sbjct: 120 GKRWKRLRTLSSPSFSNNSLRKVRNSVQECGTEIL--WNIEQKVRKNEDIDMLIVYQEYT 177 Query: 714 GDVISRTAFGSN----------------FQEGMKIFQLQG------ELSERLIQAFQTLF 827 VISR A G + F +F + G + ++ + F Sbjct: 178 LGVISRIALGQSESNMFKNPLLPKVQAIFNGSWHVFLITGIFPPLAGVFRKMSKMLPASF 237 Query: 828 IPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSN 1007 IP + F ID+ + ++G+ + + + + Sbjct: 238 IPAFKIFDLIEVAVQARIDQRAKDEIKGVEPGEPQDFIDLFLDARVPDVKILSGEANEDF 297 Query: 1008 GKA-----NLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHY 1172 K+ N L+ ++II +C +F AG +TT++ L++ +L+ HPE Q K +EEV Sbjct: 298 AKSSVVKINKELTFDEIIAQCFVFLAAGFDTTALSLSYATYLLATHPEIQTKLQEEV--- 354 Query: 1173 FGRTTPD----FESLSRLKIVTMIFYEVLRLYP-PITFLTRRTYKAMELGGIKYPAGVNL 1337 R PD F+ LS+LK + + E LRLYP T TR+ + + G+ + G+N+ Sbjct: 355 -DRECPDPEIFFDHLSKLKYLECVMKETLRLYPLGTTANTRKCMRETTINGVNFDEGMNI 413 Query: 1338 MLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEA 1517 + +HH+P IWG+D +F PER+ +G + ++ PFG GPR CIG A E Sbjct: 414 QVDTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQ 473 Query: 1518 KMALSTILQRFSF 1556 K+ L+ IL+ +SF Sbjct: 474 KILLAQILKEYSF 486
>Q8SPK1:CP4AO_PIG Cytochrome P450 4A24 - Sus scrofa (Pig)| Length = 504 Score = 161 bits (407), Expect = 1e-38 Identities = 133/455 (29%), Positives = 216/455 (47%), Gaps = 21/455 (4%) Frame = +3 Query: 342 LPMFTNAIKEHGKVSFTW-FGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN- 515 LP ++++ W +G V+V DP+ ++ +L+ +++ + RLL Sbjct: 66 LPPLLKRVEKYPSACALWRWGTRAMVLVYDPDYMKVVLARS-----DPKNSVVYRLLIPW 120 Query: 516 ---GLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 GL G+ W + RR+L PAFH++ +K + + + + M+ +WE ++ E+ Sbjct: 121 IGCGLLLLNGQTWFQRRRMLTPAFHYDILKPYVGLMAKSVQVMLDKWEQLVAQDPRLEI- 179 Query: 687 VCPEFQNLTGDVISRTAF---GSNFQEG------MKIFQLQGELSERLIQAFQTLFIPGY 839 V P +T D I + AF GS +G I+ L+ S R AF I Y Sbjct: 180 VGP-VSLMTLDTIMKCAFSHQGSAQTDGDSHSYIQAIWDLKNLFSIRTKSAFLQNDII-Y 237 Query: 840 WFFPT--KNNRRMRAIDREIRMI--LRGIIGKKERAIKNXXXXXXXXXXXXXX-SNMQQS 1004 P KN+R R + + LR +K+ ++N + M++ Sbjct: 238 RLSPEGRKNHRAARIAHQHTDRVIQLRKAQLQKQGEMENVRKKRHLDFLDILLLARMEKG 297 Query: 1005 NGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR- 1181 N LS D+ E F F G +TT+ ++W L L+ HPE Q++ REE+ G Sbjct: 298 NS-----LSDTDLRAEVDTFMFEGHDTTASGISWILYALASHPEHQQRCREEIQGLLGDG 352 Query: 1182 TTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFI 1358 T+ ++ L ++ TM E LRLYPP+ ++R K + G PAG+ L L I + Sbjct: 353 TSITWDHLDQMPYTTMCIKEALRLYPPVPGVSRELSKPITFPDGRSLPAGITLSLSIYGL 412 Query: 1359 HHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTI 1538 HH+P +W + EF+P RFA G +A+ AF PF GG R CIG+ FA+ E K+A++ Sbjct: 413 HHNPQVW-PNPEEFDPSRFAPG---SARHSHAFMPFSGGSRNCIGKQFAMNEMKVAVALT 468 Query: 1539 LQRFSFELSPSYIHAPYTVITLQPQHGAQIRLKKI 1643 L RF PS + L ++G ++L+K+ Sbjct: 469 LLRFELAPDPSRKPIATPEVVLNSKNGIHLKLRKL 503
>P98187:CP4F8_HUMAN Cytochrome P450 4F8 - Homo sapiens (Human)| Length = 520 Score = 160 bits (404), Expect = 2e-38 Identities = 135/458 (29%), Positives = 208/458 (45%), Gaps = 24/458 (5%) Frame = +3 Query: 342 LPMFTNAIKEHGKVSFTWFGP-TPRVMVPDPELVREILSNKFGHFGKQRS--TRIGRLLA 512 L + T + + + W GP TP + + P++VR +++ K + L Sbjct: 74 LRVLTQLVATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLG 133 Query: 513 NGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVC 692 +GL G+KW HRR+L PAFH +K + +FS M +W+ ++ +G +DV Sbjct: 134 DGLLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQR-LAMEGSTCLDVF 192 Query: 693 PEFQNLTGDVISRT--AFGSNFQEGMK-----IFQLQGELSERLIQAFQTLFIPGYWFFP 851 +T D + + +F SN QE I +L + +R Q F+ + +F Sbjct: 193 EHISLMTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFFR---YKDFLYFL 249 Query: 852 TKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSN--------MQQSN 1007 T RR R + +I ++ R + + + + N Sbjct: 250 TPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVLLLSEDKN 309 Query: 1008 GKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTT 1187 GK LS EDI E F F G +TT+ L+W L L+ HPE+QE+ R+EV Sbjct: 310 GKE---LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRE 366 Query: 1188 P---DFESLSRLKIVTMIFYEVLRLYPPI-TFLTRRTYKAMELGGIKYPAGVNLMLPILF 1355 P +++ L++L +TM E LRL+PPI TF T + P G + I Sbjct: 367 PKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVCNINIFA 426 Query: 1356 IHHDPDIWGKDAREFNPERFADGISNAAKR-PAAFFPFGGGPRICIGQNFALQEAKMALS 1532 IHH+P +W D ++P RF NA KR P AF PF GPR CIGQ FA+ E K+ L+ Sbjct: 427 IHHNPSVW-PDPEVYDPFRFDP--ENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLA 483 Query: 1533 TILQRFSFELSPSYIHAPYT-VITLQPQHGAQIRLKKI 1643 L R F + P + T I L+ + G +R++ + Sbjct: 484 LTLLR--FRILPDHREPRRTPEIVLRAEDGLWLRVEPL 519
>Q29496:CP3AO_SHEEP Cytochrome P450 3A24 - Ovis aries (Sheep)| Length = 503 Score = 159 bits (403), Expect = 3e-38 Identities = 122/444 (27%), Positives = 210/444 (47%), Gaps = 35/444 (7%) Frame = +3 Query: 333 PRVLPMFTNAI--------------KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FG 467 PR LP F N + K++GK+ + G P +++ DP++++ +L + + Sbjct: 41 PRPLPYFGNVLSYRKGVCEFDEECFKKYGKMWGVFEGKQPLLVITDPDVIKTVLVKECYS 100 Query: 468 HFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRW 647 F +R ++ N ++ E E+W + R +L+P F K+K M P+ + ++ Sbjct: 101 VFTNRRVFGPMGIMKNAVSVAEDEQWKRIRTLLSPTFTSGKLKDMFPIIGKYGDVLVRNL 160 Query: 648 ENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSN----------FQEGMKI--------- 770 A+ V++ F + DVI+ T+FG N F E K Sbjct: 161 RKE--AEKGKSVNMKDIFGAYSMDVITSTSFGVNIDSLGNPQDPFVENAKKLLRFNILDP 218 Query: 771 FQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXX 950 F L L L+ F+ L I FP A+D + + R K+ R N Sbjct: 219 FLLSVVLFPFLVPIFEVLNIT---MFPKS------AVDFLTKSVKRI---KESRLKDNQK 266 Query: 951 XXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMH 1130 N ++++ + LS ++++ + +F FAG ETTS L++ L +L+ H Sbjct: 267 PRVDFLQLMINSQNSKETDN--HKALSDQELMAQSVIFIFAGYETTSNTLSFLLYILATH 324 Query: 1131 PEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELG 1307 P+ Q+K +EE+ F + P ++ L++++ + M+ E LR++P L R K +E+ Sbjct: 325 PDVQQKLQEEIDATFPNKAPPTYDVLAQMEYLDMVVNETLRMFPIAVRLDRLCKKDVEIH 384 Query: 1308 GIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRIC 1487 G+ P G + +PI +H DP +W + EF PERF+ ++ P + PFG GPR C Sbjct: 385 GVSIPKGTAVTVPIFVLHRDPQLW-PEPEEFRPERFSKKNKDSI-NPYVYLPFGTGPRNC 442 Query: 1488 IGQNFALQEAKMALSTILQRFSFE 1559 IG FA+ K+A+ +LQ FSF+ Sbjct: 443 IGMRFAIMNMKLAIVRVLQNFSFK 466
>Q6NT55:CP4FN_HUMAN Cytochrome P450 4F22 - Homo sapiens (Human)| Length = 531 Score = 159 bits (401), Expect = 5e-38 Identities = 121/443 (27%), Positives = 210/443 (47%), Gaps = 22/443 (4%) Frame = +3 Query: 381 VSFTWFGPT-PRVMVPDPELVREILSNKFGHFGKQRSTRIGRL---LANGLANHEGEKWA 548 V W GP P +++ P+ ++ +L K G L L +GL +G+KW+ Sbjct: 95 VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKD-DLFYGFLKPWLGDGLLLSKGDKWS 153 Query: 549 KHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVIS 728 +HRR+L PAFH + +K + +F+ + M +W + ++ +D+ +T D + Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRH-LAEGSAVSLDMFEHISLMTLDSLQ 212 Query: 729 RTAF--GSNFQEGMK-----IFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDR 887 + F SN QE M I +L R + L + ++ + + RR R Sbjct: 213 KCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHYL---DFIYYRSADGRRFRQACD 269 Query: 888 EIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNM-------QQSNGKANLGLSIEDII 1046 + +I ++ RA++ + + +GK LS EDI Sbjct: 270 MVHHFTTEVIQERRRALRQQGAEAWLKAKQGKTLDFIDVLLLARDEDGKE---LSDEDIR 326 Query: 1047 QECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFE--SLSRLK 1217 E F F G +TTS ++W L L+ +PE+QEK REE+ GR + E L++L Sbjct: 327 AEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLP 386 Query: 1218 IVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAR 1394 TM E LR YPP+T ++R+ + ++L G P G+ ++ I HH+P +W D++ Sbjct: 387 FTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVW-PDSK 445 Query: 1395 EFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSY 1574 +NP RF D + + P A+ PF GPR CIGQ+FA+ E ++ ++ L RF + + Sbjct: 446 VYNPYRF-DPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTR 504 Query: 1575 IHAPYTVITLQPQHGAQIRLKKI 1643 + L+ ++G ++++ + Sbjct: 505 KVRRKPELILRTENGLWLKVEPL 527
>Q3MID2:CP4F3_RAT Cytochrome P450 4F3 - Rattus norvegicus (Rat)| Length = 524 Score = 159 bits (401), Expect = 5e-38 Identities = 121/402 (30%), Positives = 189/402 (47%), Gaps = 16/402 (3%) Frame = +3 Query: 393 WFGPT-PRVMVPDPELVREILSNKFGHFGKQRSTR--IGRLLANGLANHEGEKWAKHRRI 563 W GP P + + P ++ ++ K R + L +GL G+KW++HRR+ Sbjct: 91 WVGPWHPVIRIFHPAFIKPVILAPASVAPKDRVFYRFLRPWLGDGLLLSTGDKWSRHRRM 150 Query: 564 LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG 743 L PAFH +K + +F+ M +W+ +++QG +D+ +T D + + F Sbjct: 151 LTPAFHFNILKPYVKIFNDSTNIMHAKWQR-LASQGSARLDMFEHISLMTLDSLQKCVFS 209 Query: 744 --SNFQEG-MKIFQLQGELSERLIQAFQTLFIPGYWFFP-TKNNRRMRAIDREIRMILRG 911 SN QE + ELS + + Q+L + F+ T++ R R R + Sbjct: 210 FDSNCQEKPSEYITAILELSALVARRHQSLLLHVDLFYHLTRDGMRFRKACRLVHDFTDA 269 Query: 912 IIGKKERAIKNXXXXXXXXXXXXXXSN-----MQQSNGKANLGLSIEDIIQECKLFYFAG 1076 +I ++ + + + + S + LS EDI E F F G Sbjct: 270 VIRERRCTLPDQGGDDALKAKAKAKTLDFIDVLLLSKDEHGEALSDEDIRAEADTFMFGG 329 Query: 1077 METTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD---FESLSRLKIVTMIFYEVL 1247 +TT+ L+W L L+ HPE+QE+ R+EV P+ ++ L++L +TM E L Sbjct: 330 HDTTASGLSWILYNLAKHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESL 389 Query: 1248 RLYPPITFLTRR-TYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADG 1424 RL+PP T ++R T M G P GV + I HH+P +W D +NP RF D Sbjct: 390 RLHPPATAISRCCTQDIMLPDGRVIPKGVICRISIFGTHHNPAVW-PDPEVYNPFRF-DA 447 Query: 1425 ISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 + + P AF PF GPR CIGQ FA+ E K+AL+ L RF Sbjct: 448 DNGKGRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRF 489
>Q43078:C97B1_PEA Cytochrome P450 97B1 - Pisum sativum (Garden pea)| Length = 552 Score = 158 bits (399), Expect = 8e-38 Identities = 124/434 (28%), Positives = 196/434 (45%), Gaps = 47/434 (10%) Frame = +3 Query: 369 EHGKVSFTWFGPTPRVMVPDPELVREIL-SNKFGHFGKQRSTRIGRLLANGLANHEGEKW 545 EHG V FGP V+V DP + R IL N F + + + ++ GL + E W Sbjct: 113 EHGSVYKLAFGPKAFVVVSDPIVARHILRENAFSYDKGVLADILEPIMGKGLIPADLETW 172 Query: 546 AKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGL-----CEVDVCPEFQNL 710 + RR++ P FH ++ M+ +F++C E + + + +G E+D+ EF NL Sbjct: 173 KQRRRVIAPGFHTSYLEAMVQLFTSCSERTVLKVNELLEGEGRDGQKSVELDLEAEFSNL 232 Query: 711 TGDVISRTAFGSNF----QEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKN--NRRM 872 ++I F +F E I + G L E + T +IP YW FP R Sbjct: 233 ALEIIGLGVFNYDFGSVTNESPVIKAVYGTLFEA--EHRSTFYIP-YWKFPLARWIVPRQ 289 Query: 873 RAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANL----GLSIED 1040 R ++++I + G A ++ SN++ ++ L G+ ++D Sbjct: 290 RKFQDDLKVINTCLDGLIRNAKESRQETDVEKLQQRDYSNLKDASLLRFLVDMRGVDVDD 349 Query: 1041 --IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRL 1214 + + AG ETT+ +LTW + +L+ +P+ +KA+ EV G P FE L +L Sbjct: 350 RQLRDDLMTMLIAGHETTAAVLTWAVFLLAQNPDKMKKAQAEVDLVLGMGKPTFELLKKL 409 Query: 1215 KIVTMIFYEVLRLYPPITFLTRRTYKAMEL--------GGIKYPAGVNLMLPILFIHHDP 1370 + + +I E LRLYP L RR+ K L G PAG ++ + + +H P Sbjct: 410 EYIRLIVVETLRLYPQPPLLIRRSLKPDVLPGGHKGDKDGYTIPAGTDVFISVYNLHRSP 469 Query: 1371 DIWGKDAREFNPERFADGISN----------AAKRPA-----------AFFPFGGGPRIC 1487 W + +F PERF +N ++ P AF PFGGGPR C Sbjct: 470 YFWDR-PNDFEPERFLVQNNNEEVEGWAGFDPSRSPGALYPNEIISDFAFLPFGGGPRKC 528 Query: 1488 IGQNFALQEAKMAL 1529 +G FAL E+ +AL Sbjct: 529 VGDQFALMESTVAL 542
>Q64459:CP3AB_MOUSE Cytochrome P450 3A11 - Mus musculus (Mouse)| Length = 504 Score = 157 bits (398), Expect = 1e-37 Identities = 111/409 (27%), Positives = 196/409 (47%), Gaps = 11/409 (2%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK + G TP + V DPE ++ +L + F F +R +++ ++ + ++ Sbjct: 66 KKYGKTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVGIMSKAISISKDDE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRW-ENSMSAQGLCEVDVCPEFQNLTGD 719 W ++R +L+P F K+K M PV + ++ + + + + DV + D Sbjct: 126 WKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSM---D 182 Query: 720 VISRTAFGSNFQEGMKIFQLQGELSERLIQ-------AFQTLFIPGYWFFPTKNNRRMRA 878 VI+ T+FG N E +++L++ F + P + P + Sbjct: 183 VITSTSFGVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFP--FLTPVYEMLNICM 240 Query: 879 IDRE-IRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQEC 1055 ++ I + + KE + + S+ + ++ LS +I + Sbjct: 241 FPKDSIEFFKKFVDRMKESRLDSKQKHRVDFLQLMMNSHNNSKDKVSHKALSDMEITAQS 300 Query: 1056 KLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMI 1232 +F FAG ETTS L++TL L+ HP+ Q+K ++E+ + P ++++ ++ + M+ Sbjct: 301 IIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMV 360 Query: 1233 FYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 E LRLYP L R K +EL G+ P G +M+P +HHDP W + EF PER Sbjct: 361 LNETLRLYPIANRLERVCKKDVELNGVYIPKGSTVMIPSYALHHDPQHW-SEPEEFQPER 419 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 F+ + + P + PFG GPR C+G FAL K+AL+ I+Q FSF+ Sbjct: 420 FSKE-NKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQ 467
>P20815:CP3A5_HUMAN Cytochrome P450 3A5 - Homo sapiens (Human)| Length = 502 Score = 157 bits (398), Expect = 1e-37 Identities = 111/414 (26%), Positives = 195/414 (47%), Gaps = 12/414 (2%) Frame = +3 Query: 354 TNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANH 530 T K++GK+ T+ G P + + DP+++R +L + + F +RS + + ++ Sbjct: 62 TECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLA 121 Query: 531 EGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNL 710 E E+W + R +L+P F K+K M P+ + + ++ A+ V + F Sbjct: 122 EDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRRE--AEKGKPVTLKDIFGAY 179 Query: 711 TGDVISRTAFGSN----------FQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKN 860 + DVI+ T+FG N F E K F G L + F+ P Sbjct: 180 SMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLT-----PVFE 234 Query: 861 NRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIED 1040 + ++ L + + +++ N + +++ LS + Sbjct: 235 ALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLE 294 Query: 1041 IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLK 1217 + + +F FAG ETTS +L++TL L+ HP+ Q+K ++E+ + P ++++ +++ Sbjct: 295 LAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQME 354 Query: 1218 IVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDARE 1397 + M+ E LRL+P L R K +E+ G+ P G +++P +HHDP W + E Sbjct: 355 YLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYW-TEPEE 413 Query: 1398 FNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 F PERF+ + P + PFG GPR CIG FAL K+AL +LQ FSF+ Sbjct: 414 FRPERFSK--KKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 465
>Q8SPK0:CP4AP_PIG Cytochrome P450 4A25 - Sus scrofa (Pig)| Length = 504 Score = 157 bits (397), Expect = 1e-37 Identities = 129/436 (29%), Positives = 209/436 (47%), Gaps = 20/436 (4%) Frame = +3 Query: 396 FGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN----GLANHEGEKWAKHRRI 563 +G V+V DP+ ++ +L+ + ++ + RLL GL G+ W + RR+ Sbjct: 85 WGTRAMVLVYDPDYMKVVLARS-----EPKAPVLYRLLIPWIGCGLLLLNGQTWFQRRRM 139 Query: 564 LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAF- 740 L PAFH++ +K + + + + M+ +WE ++ E+ V P +T D I + AF Sbjct: 140 LTPAFHYDILKPYVGLMAKSVQVMLDKWEQLVAQDPRLEI-VGP-VSLMTLDTIMKCAFS 197 Query: 741 --GSNFQEG------MKIFQLQGELSERLIQAFQTLFIPGYWFFPT--KNNRRMRAIDRE 890 GS +G I+ L+ S R AF I Y P KN+R R + Sbjct: 198 HQGSAQTDGDSHSYIQAIWDLKNLFSIRTKSAFLQNDII-YRLSPEGRKNHRAARIAHQH 256 Query: 891 IRMI--LRGIIGKKERAIKNXXXXXXXXXXXXXX-SNMQQSNGKANLGLSIEDIIQECKL 1061 + LR +K+ ++N + M++ N LS D+ E Sbjct: 257 TDRVIQLRKAQLQKQGEMENVRKKRHLDFLDILLLARMEKGNS-----LSDTDLRAEVDT 311 Query: 1062 FYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIFY 1238 F F G +TT+ ++W L L+ HPE Q++ REE+ G T+ ++ L ++ TM Sbjct: 312 FMFEGHDTTASGISWILYALASHPEHQQRCREEIQGLLGDGTSITWDHLDQMPYTTMCIK 371 Query: 1239 EVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 E LRLYPP+ ++R K + G PAG+ L L + +HH+P +W + EF+P RF Sbjct: 372 EALRLYPPVPGVSRELSKPITFPDGRSLPAGIILSLSVYSLHHNPQVW-PNPEEFDPSRF 430 Query: 1416 ADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTV 1595 A G +A+ AF PF GG R CIG+ FA+ E K+A++ L RF PS Sbjct: 431 APG---SARHSHAFMPFSGGSRNCIGKQFAMNEMKVAVALTLLRFELAPDPSRKPTVIPE 487 Query: 1596 ITLQPQHGAQIRLKKI 1643 + L ++G ++L+K+ Sbjct: 488 VVLHSKNGIHLKLRKL 503
>P78329:CP4F2_HUMAN Cytochrome P450 4F2 - Homo sapiens (Human)| Length = 520 Score = 156 bits (395), Expect = 2e-37 Identities = 113/405 (27%), Positives = 195/405 (48%), Gaps = 19/405 (4%) Frame = +3 Query: 393 WFGP-TPRVMVPDPELVREILSNKFGHFGKQRS--TRIGRLLANGLANHEGEKWAKHRRI 563 W GP +P + + P+++R +++ K + + + L +GL G+KW++HRR+ Sbjct: 91 WMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRM 150 Query: 564 LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG 743 L PAFH +K + +F+ M +W+ ++++G +D+ +T D + + F Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQ-LLASEGSACLDMFEHISLMTLDSLQKCVFS 209 Query: 744 --SNFQEGMK-----IFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMI 902 S+ QE I +L +S+R + L + ++ T + +R R R + Sbjct: 210 FDSHCQEKPSEYIAAILELSALVSKR---HHEILLHIDFLYYLTPDGQRFRRACRLVHDF 266 Query: 903 LRGIIGKKERAIKNXXXXXXXXXXXXXXSN-----MQQSNGKANLGLSIEDIIQECKLFY 1067 +I ++ R + + + + S + LS EDI E F Sbjct: 267 TDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFM 326 Query: 1068 FAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP---DFESLSRLKIVTMIFY 1238 F G +TT+ L+W L L+ HPE+QE+ R+EV P +++ L+ L +TM Sbjct: 327 FEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMK 386 Query: 1239 EVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 E LRL+PP+ ++R + + L G P G+ ++ + HH+P +W D ++P RF Sbjct: 387 ESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRF 445 Query: 1416 ADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 D + + P AF PF GPR CIGQ FA+ E K+ L+ L RF Sbjct: 446 -DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRF 489
>Q27520:C13A1_CAEEL Putative cytochrome P450 CYP13A1 - Caenorhabditis elegans| Length = 519 Score = 155 bits (392), Expect = 5e-37 Identities = 121/431 (28%), Positives = 200/431 (46%), Gaps = 33/431 (7%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF-GKQRSTRIG---RLLANGLANHE 533 K+ GK+ G +++ DPELV E+ ++ +F G++R+ G + L + Sbjct: 63 KKFGKIYGFTEGTLKTLVISDPELVHEVFVTQYDNFYGRKRNPIQGDSEKEKRTNLFAAQ 122 Query: 534 GEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLT 713 G +W + R I +P F + ++++ E++ E + G ++D+ +Q T Sbjct: 123 GFRWKRLRAISSPTFSNSSLRKLYQTVEDSALELLRHIEKQSA--GGKQIDMLKFYQEFT 180 Query: 714 GDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPT-----------KN 860 DVI R A G + K + +S+ F LF+ G FPT KN Sbjct: 181 LDVIGRIAMGQTDSQMFKN-PIMPIVSKLFQGNFAKLFLIG-GIFPTFLVEIIRQILLKN 238 Query: 861 NR--RMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQ--------QSNG 1010 + R I+ + I ++E KN + + ++NG Sbjct: 239 LKVGSFRKINEITLDAIHNRIKQREEDQKNGIEIGEPADFIDLFLDAKAEDVEHFGENNG 298 Query: 1011 K-------ANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLH 1169 N L+ E+I+ +C +F AG +TT++ L++ +L+ HPE Q+K +EEV Sbjct: 299 DFSKSTTYTNRQLTTEEIVGQCTVFLIAGFDTTALSLSYATYLLATHPEIQKKLQEEVNR 358 Query: 1170 YFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFL-TRRTYKAMELGGIKYPAGVNLMLP 1346 + LS+LK + +F E LRLYP F +RR + +LG +K G + + Sbjct: 359 ECPNPEVTIDQLSKLKYMECVFKEALRLYPLGAFANSRRCMRNTKLGNMKVEVGTMIQVD 418 Query: 1347 ILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMA 1526 +H DP+IWG DA +F PER+ S+ + + + PFG GPR CIG A E K+ Sbjct: 419 TWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQKSGYIPFGLGPRQCIGMRLAYMEEKIL 478 Query: 1527 LSTILQRFSFE 1559 L IL++F+FE Sbjct: 479 LVHILRKFTFE 489
>Q99N16:CP4F3_MOUSE Cytochrome P450 4F3 - Mus musculus (Mouse)| Length = 524 Score = 155 bits (391), Expect = 7e-37 Identities = 113/364 (31%), Positives = 179/364 (49%), Gaps = 16/364 (4%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 L +GL G+KW++HRR+L PAFH +K + VF+ M +W+ ++++G ++ Sbjct: 132 LGDGLLMSTGDKWSRHRRMLTPAFHFNILKPYVKVFNDSTNIMHAKWQR-LASKGSAYLN 190 Query: 687 VCPEFQNLTGDVISRTAFG--SNFQEG-MKIFQLQGELSERLIQAFQTLFIP-GYWFFPT 854 + +T D + + F SN QE + ELS + + Q L + +++ T Sbjct: 191 MFEHISLMTLDSLQKCVFSFDSNCQEKPSEYITAILELSALVARRHQRLLLHVDLFYYLT 250 Query: 855 KNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSN--------MQQSNG 1010 + R R R + +I ++ R + + + + +G Sbjct: 251 HDGMRFRKACRLVHDFTDAVIRERRRTLLDQGGDDVLKAKAKAKTLDFIDVLLLSKDEHG 310 Query: 1011 KANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP 1190 KA LS EDI E F F G +TT+ L+W L L+ HPE+QE+ R+EV P Sbjct: 311 KA---LSDEDIRAEADTFMFGGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDREP 367 Query: 1191 D---FESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFI 1358 + ++ L++L +TM E LRL+PP+T ++R + + L G P GV + I Sbjct: 368 EEIEWDDLAQLPFLTMCIKESLRLHPPVTAISRCCTQDIVLPDGRVIPKGVISRISIFGT 427 Query: 1359 HHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTI 1538 HH+P +W D ++P RF D + + P AF PF GPR CIGQ FA+ E K+AL+ Sbjct: 428 HHNPAVW-PDPEVYDPFRF-DADNVKGRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALT 485 Query: 1539 LQRF 1550 L RF Sbjct: 486 LLRF 489
>P15128:CP4B1_RABIT Cytochrome P450 4B1 - Oryctolagus cuniculus (Rabbit)| Length = 506 Score = 155 bits (391), Expect = 7e-37 Identities = 114/402 (28%), Positives = 191/402 (47%), Gaps = 23/402 (5%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCE-- 680 + GL +G KW +HR++L P FH++ +K + +F+ M+ +WE CE Sbjct: 117 IGKGLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFADSTRIMLEKWEKKA-----CEGK 171 Query: 681 -VDVCPEFQNLTGDVISRTAFG----------SNFQEGMKIFQLQGELSERLIQAFQTLF 827 D+ + ++ D + + FG S++ + L L ++ I +FQ Sbjct: 172 SFDIFSDVGHMALDTLMKCTFGKGDSGLNHRDSSYYVAVSELTL---LMQQRIDSFQYHN 228 Query: 828 IPGYWFFPTKNNRRMRAI-------DREIRMILRGIIGKKERA-IKNXXXXXXXXXXXXX 983 YW P R +RA DR IR + +KER I+N Sbjct: 229 DFIYWLTP-HGRRFLRACRAAHDHTDRVIRQRKAALQDEKEREKIQNRRHLDFLDI---- 283 Query: 984 XSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV 1163 + G++ + LS D+ E F F G +TT+ ++W L ++++PE Q++ REEV Sbjct: 284 ---LLDVRGESGVQLSDTDLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQRCREEV 340 Query: 1164 LHYFG-RTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAME-LGGIKYPAGVNL 1337 G + + +E L+++ +TM E RLYPP+ + R+ K + + G PAG + Sbjct: 341 REILGDQDSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPVSFVDGRSLPAGSLI 400 Query: 1338 MLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEA 1517 L I +H + D+W D F+P RF+ +++ + P AF PF GPR CIGQ FA+ E Sbjct: 401 SLHIYALHRNSDVW-PDPEVFDPLRFSPE-NSSGRHPYAFIPFSAGPRNCIGQQFAMNEM 458 Query: 1518 KMALSTILQRFSFELSPSYIHAPYTVITLQPQHGAQIRLKKI 1643 K+ + L RF F + P + + L+ ++G + LK + Sbjct: 459 KVVTALCLLRFEFSVDPLRLPIKLPQLVLRSKNGIHLYLKPL 500
>Q9GJX5:CP4AL_PIG Cytochrome P450 4A21 - Sus scrofa (Pig)| Length = 504 Score = 155 bits (391), Expect = 7e-37 Identities = 131/439 (29%), Positives = 209/439 (47%), Gaps = 23/439 (5%) Frame = +3 Query: 396 FGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN----GLANHEGEKWAKHRRI 563 +G V+V DP+ ++ +L+ + ++ + RLL GL G+ W + RR+ Sbjct: 85 WGTRAMVLVYDPDYMKVVLARS-----EPKAPVLYRLLIPWIGCGLLLLNGQMWFQRRRM 139 Query: 564 LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAF- 740 L PAFH++ +K + + + + M+ +WE ++ E+ V P +T D I + AF Sbjct: 140 LTPAFHYDILKPYVGLMAKSVQVMLDKWEQLVAQDPRLEI-VGP-VSLMTLDTIMKCAFS 197 Query: 741 --GSNFQEG------MKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAI----- 881 GS +G I+ L+ + RL AF I + + + RA Sbjct: 198 HQGSAQTDGDSQSYIQAIWDLKNLIFSRLRSAFLQNDI--IYRLSPEGRQCQRACQKVHQ 255 Query: 882 --DREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXX-SNMQQSNGKANLGLSIEDIIQE 1052 DR I+ LR +KE ++N + M+ N LS D+ E Sbjct: 256 HTDRVIQ--LRKTHLQKEGEMENVKKKRHLDFLDILLFARMENGNS-----LSDTDVRAE 308 Query: 1053 CKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTM 1229 F AG ++T+ ++W L L+ +PE Q++ REE+ G T+ ++ L ++ TM Sbjct: 309 VDTFMAAGHDSTASGISWVLYALASNPEHQQRCREEIQGLLGDGTSITWDHLDQMPYTTM 368 Query: 1230 IFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNP 1406 E LRLYPP+ + R K + G PAG+ L L I +HH+P +W + EF+P Sbjct: 369 CIKEALRLYPPVPSVGRELSKPITFPDGRSLPAGIILSLSIYGLHHNPQVW-PNPEEFDP 427 Query: 1407 ERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAP 1586 RFA G +A+ AF PF GG R CIG+ FA+ E K+ ++ L RF PS I P Sbjct: 428 SRFAPG---SARHSHAFMPFSGGSRNCIGKQFAMNEMKVVVALTLLRFELAPDPSRIPVP 484 Query: 1587 YTVITLQPQHGAQIRLKKI 1643 I L+ ++G + L+KI Sbjct: 485 IQGIVLKSKNGIHLNLRKI 503
>Q8N118:CP4X1_HUMAN Cytochrome P450 4X1 - Homo sapiens (Human)| Length = 509 Score = 154 bits (390), Expect = 9e-37 Identities = 121/438 (27%), Positives = 200/438 (45%), Gaps = 18/438 (4%) Frame = +3 Query: 393 WFGPTPRVM-VPDPELVREILSNKFGHFGKQRSTRIGR----LLANGLANHEGEKWAKHR 557 W GP + DP+ + +LS +S + + LL GLA +G KW +HR Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSRT-----DPKSQYLQKFSPPLLGKGLAALDGPKWFQHR 137 Query: 558 RILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTA 737 R+L P FH +K + V + + M+ +WE S Q V+V +++ D+I + A Sbjct: 138 RLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQD-TSVEVYEHINSMSLDIIMKCA 196 Query: 738 FG--SNFQE-------GMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDRE 890 F +N Q IF+L + RL + L+ F + R + + R Sbjct: 197 FSKETNCQTNSTHDPYAKAIFELSKIIFHRL---YSLLYHSDIIFKLSPQGYRFQKLSRV 253 Query: 891 IRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDI--IQECKLF 1064 + II +++++++ + K G S DI E F Sbjct: 254 LNQYTDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTF 313 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG-RTTPDFESLSRLKIVTMIFYE 1241 AG +T + ++W L L+++PE QE+ REEV G ++ ++ L + TM E Sbjct: 314 LLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKE 373 Query: 1242 VLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFA 1418 RL P + ++R K + G PAG+ ++L I +HH+P +W K+ + F+P RF+ Sbjct: 374 TCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVW-KNPKVFDPLRFS 432 Query: 1419 DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVI 1598 S+ + P A+ PF G R CIGQ FA+ E K+ ++ IL F P+ Sbjct: 433 QENSD-QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHF 491 Query: 1599 TLQPQHGAQIRLKKI*AC 1652 L+P++G + LKK+ C Sbjct: 492 ILKPKNGMYLHLKKLSEC 509
>Q9EP75:CP4FE_MOUSE Cytochrome P450 4F14 - Mus musculus (Mouse)| Length = 524 Score = 154 bits (389), Expect = 1e-36 Identities = 120/405 (29%), Positives = 189/405 (46%), Gaps = 19/405 (4%) Frame = +3 Query: 393 WFGP-TPRVMVPDPELVREILSNKFGHFGKQRS--TRIGRLLANGLANHEGEKWAKHRRI 563 W GP P + + ++VR IL+ K + + L +GL G+KW++HRR+ Sbjct: 91 WIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYSILKPWLGDGLLVSAGDKWSRHRRM 150 Query: 564 LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG 743 L PAFH +K + +F+ M +W+ +S G +D+ +T D + + F Sbjct: 151 LTPAFHFNILKPYVKIFNDSTNIMHAKWQRLIS-DGSARLDMFEHVSLMTLDSLQKCVFS 209 Query: 744 --SNFQEGMK-----IFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMI 902 SN QE I +L +++R Q L + T + R R + Sbjct: 210 FDSNCQEKSSEYIAAILELSALVAKR---HQQPLMFMDLLYNLTPDGMRFRKACNVVHEF 266 Query: 903 LRGIIGKKERAIKNXXXXXXXXXXXXXXSN-----MQQSNGKANLGLSIEDIIQECKLFY 1067 +I ++ R + + + + S + LS EDI E F Sbjct: 267 TDAVIRERHRTLPDQGLDDFLKSKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFM 326 Query: 1068 FAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD---FESLSRLKIVTMIFY 1238 F G +TT+ L+W L L+ HPE+QE+ R+EV P+ ++ L++L +TM Sbjct: 327 FEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRGREPEEIEWDDLAQLPFLTMCIK 386 Query: 1239 EVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 E LRL+PP+T ++R + + L G P G+ ++ I IHH+P +W D ++P RF Sbjct: 387 ESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYDPFRF 445 Query: 1416 ADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 D + P AF PF GPR CIGQ FA+ E K+AL+ L RF Sbjct: 446 -DPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRF 489
>Q9VG40:CP134_DROME Probable cytochrome P450 313a4 - Drosophila melanogaster (Fruit fly)| Length = 478 Score = 154 bits (388), Expect = 2e-36 Identities = 115/417 (27%), Positives = 201/417 (48%), Gaps = 8/417 (1%) Frame = +3 Query: 339 VLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKF----GHFGKQRSTRIGRL 506 +L F + +HG F+W GP P ++V DP++V++I ++ G K G Sbjct: 53 ILNAFGCFLDKHGPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGV- 111 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 GL + + +W+ HR++LNPAF H+ + LP+F+ ++ + E Q E D Sbjct: 112 ---GLFSLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLE---PLQDDGEKD 165 Query: 687 VCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNR 866 + P Q+ T + ++T GS+ ++ + S L+ +Q F K + Sbjct: 166 LIPLLQSFTLGIATQTTMGSDVKDE------ESFRSNSLLGRYQCRFCRQ---LAGKESH 216 Query: 867 RMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDII 1046 +A EIR +R II +K + N+ + + +++++ Sbjct: 217 YYQA-KTEIRQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGV-FTLKNVE 274 Query: 1047 QECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRT---TPDFESLSRLK 1217 E + F ETT+ + +TL++L+M PE+QE+A EE+ F T + ++ Sbjct: 275 DESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMV 334 Query: 1218 IVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAR 1394 + +I E +R+ PP+ ++R+T + ++L GI P GV + + I +H IWG DA Sbjct: 335 YLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAE 394 Query: 1395 EFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELS 1565 FNP+ F + K P A+ PF G R CIG +AL AK+ L+ +L+ + F+ S Sbjct: 395 TFNPDHFLPH-NIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTS 450
>Q9HBI6:CP4FB_HUMAN Cytochrome P450 4F11 - Homo sapiens (Human)| Length = 524 Score = 153 bits (387), Expect = 2e-36 Identities = 118/406 (29%), Positives = 191/406 (47%), Gaps = 20/406 (4%) Frame = +3 Query: 393 WFGPT-PRVMVPDPELVREILSNKFGHFGKQRSTR--IGRLLANGLANHEGEKWAKHRRI 563 W GPT P +++ P+++R I S K + L +GL G+KW++HRR+ Sbjct: 91 WLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRM 150 Query: 564 LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG 743 L PAFH +K + +F+ M +W+ ++++G +D+ +T D + + F Sbjct: 151 LTPAFHFNILKPYMKIFNKSVNIMHDKWQR-LASEGSARLDMFEHISLMTLDSLQKCVFS 209 Query: 744 --SNFQEGMK-----IFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMI 902 SN QE I +L + +R Q L + ++ T + +R R + Sbjct: 210 FESNCQEKPSEYIAAILELSAFVEKR---NQQILLHTDFLYYLTPDGQRFRRACHLVHDF 266 Query: 903 LRGIIGKKERA-----IKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFY 1067 +I ++ R I + + S + LS EDI E F Sbjct: 267 TDAVIQERRRTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFM 326 Query: 1068 FAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP---DFESLSRLKIVTMIFY 1238 F G +TT+ L+W L L+ HPE+QE+ R+EV P +++ L++L +TM Sbjct: 327 FEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIK 386 Query: 1239 EVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 E LRL+PP+ ++R + L G P G+ ++ I+ IH++P +W D ++P RF Sbjct: 387 ESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRF 445 Query: 1416 ADGISNAAKR-PAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 N +R P AF PF GPR CIGQ FA+ E K+ L+ L F Sbjct: 446 NQ--ENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHF 489
>P33268:CP3A8_MACFA Cytochrome P450 3A8 - Macaca fascicularis (Crab eating macaque)| (Cynomolgus monkey) Length = 503 Score = 153 bits (387), Expect = 2e-36 Identities = 113/406 (27%), Positives = 199/406 (49%), Gaps = 8/406 (1%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GKV + G P + + DP +++ +L + + F +R + N ++ E E+ Sbjct: 66 KKYGKVWGFYDGRQPVLAITDPNMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+P F K+K M+P+ + + ++ A+ V + F + DV Sbjct: 126 WKRIRSLLSPTFTSGKLKEMVPIIAKYGDVLVRNLRRE--AETGKPVTLKDVFGAYSMDV 183 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSERLIQA-FQTLFIPGYWFFP----TKNNRRMRAIDR 887 I+ T+FG N E +++L++ F F FP + R Sbjct: 184 ITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITIFPFIIPILEVLNISIFPR 243 Query: 888 EIRMILRGIIGK-KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLF 1064 E+ LR + + KE +K+ S + +++ LS +++ + +F Sbjct: 244 EVTSFLRKSVKRIKESRLKDTQKHRVDFLQLMIDSQNSKET-ESHKALSDLELVAQSIIF 302 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIFYE 1241 FAG ETTS +L++ + L+ HP+ Q+K +EE+ + P ++++ +++ + M+ E Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKLQEEIDTVLPNKAPPTYDTVLQMEYLDMVVNE 362 Query: 1242 VLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFAD 1421 LR++P L R K +E+ GI P GV +M+P +HHDP W + +F PERF+ Sbjct: 363 TLRIFPIAMRLERVCKKDVEINGIFIPKGVVVMIPSYALHHDPKYW-PEPEKFLPERFSK 421 Query: 1422 GISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 +N P + PFG GPR CIG FAL K+A+ +LQ FSF+ Sbjct: 422 K-NNDNIDPYIYTPFGSGPRNCIGMRFALMNMKLAIIRVLQNFSFK 466
>Q964T1:CP4CU_BLAGE Cytochrome P450 4c21 - Blattella germanica (German cockroach)| Length = 501 Score = 153 bits (386), Expect = 3e-36 Identities = 115/406 (28%), Positives = 183/406 (45%), Gaps = 18/406 (4%) Frame = +3 Query: 393 WFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNP 572 +FG P V + PEL+ +L N L GL G KW +HR+I+ P Sbjct: 75 YFGNRPFVNISSPELIEVVLRNTQLIDKAFLYDLFHSWLGTGLLTSSGAKWHQHRKIITP 134 Query: 573 AFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNF 752 FH ++ + +F+ E ++ + + + G + N D+I TA G++ Sbjct: 135 TFHFSILEGFITIFAEKSEILVRKLQKEV---GRGPFFIRQYVSNCALDIICETAMGTSV 191 Query: 753 Q---EGMK-----IFQLQGELSER-----LIQAFQTLFIPGYWFFPTKNNRRMRAIDREI 893 EG I ++ LS+R L F P YW + + ++ ++ + Sbjct: 192 NAQDEGFSEYVTAINKMTDVLSDRMANPLLYPEFIFKLTPYYW----THKKCLKVLNGFV 247 Query: 894 RMIL--RGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFY 1067 I+ R KK + + + + + L+ DI++E F Sbjct: 248 NKIIQERKEERKKSKVTQTSEDADIGKKKRVPFLDTLLDASEDDNKLTDTDILEEVHTFM 307 Query: 1068 FAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRT--TPDFESLSRLKIVTMIFYE 1241 F G +T S +TW L L HPE QE+A +EV F + P L+ + + + E Sbjct: 308 FEGHDTVSAAMTWLLFELGHHPEIQEEAYKEVQDIFQGSDRVPTMADLNNMNYLERVIKE 367 Query: 1242 VLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF-A 1418 LRL+P + + R ++ ELGG PAG N+ + FIH +P+I+ + R FNP+ F Sbjct: 368 SLRLHPSVIYFVREAHQDFELGGYTIPAGTNIDFSVPFIHRNPEIF-PNPRCFNPDNFLP 426 Query: 1419 DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 D + N + P A+ PF GPR CIGQ FAL E K+ LS +L+ + F Sbjct: 427 DRVVN--RHPYAYIPFSAGPRNCIGQRFALLEEKVVLSYLLRHYRF 470
>Q27518:C13A2_CAEEL Putative cytochrome P450 CYP13A2 - Caenorhabditis elegans| Length = 515 Score = 153 bits (386), Expect = 3e-36 Identities = 113/431 (26%), Positives = 201/431 (46%), Gaps = 33/431 (7%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF----------GKQRSTRIGRLLAN 515 K++GKV G ++V DP +V EI +F +F ++ R+ L A Sbjct: 64 KKYGKVYGYTDGTQRTLVVADPAMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLLAA- 122 Query: 516 GLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCP 695 +G +W + R I + +F + +K+M E++ E + G ++D+ Sbjct: 123 -----QGYRWKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQTA--GGEQIDMLR 175 Query: 696 EFQNLTGDVISRTAFGSNFQEGMK--IFQLQGEL---SERLIQAFQTLFIPGYWFFPTKN 860 +Q T DVI R A G K I + E+ S + + +F P F Sbjct: 176 FYQEYTMDVIGRFAMGQTDSMMFKNPIVNVVREIFCGSRKNLMLICQVFPPIGQFIRDLT 235 Query: 861 NRRMRAIDREIRMILRGIIG------KKERAIKNXXXXXXXXXXXXXXSN---------- 992 + R ++ I++ ++ ++E+ ++ S+ Sbjct: 236 FKFPRIPAFKLYSIMQDVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEARE 295 Query: 993 -MQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLH 1169 + N K LS ++++ +C LF G +TT++ L++ +L+++P+ QEK EE+ Sbjct: 296 DFSKRNLKITKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAR 355 Query: 1170 YFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFL-TRRTYKAMELGGIKYPAGVNLMLP 1346 FG + +FE L RLK + + E LRLYP + +R+ K + G+K AGV + + Sbjct: 356 EFGTSEVEFEKLGRLKYMDCVIKEALRLYPLASISNSRKCMKTTTVNGVKIEAGVYVQMD 415 Query: 1347 ILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMA 1526 +H+DP++WG+D +EF PER++ + A+ PFG GPR CIG A+ E K+ Sbjct: 416 TWSLHYDPELWGEDVKEFKPERWS--TDEPLEHKGAYLPFGLGPRQCIGMRLAIMEQKIL 473 Query: 1527 LSTILQRFSFE 1559 L+ +L+ ++FE Sbjct: 474 LTHLLKNYTFE 484
>Q9HB55:CP343_HUMAN Cytochrome P450 3A43 - Homo sapiens (Human)| Length = 503 Score = 152 bits (384), Expect = 5e-36 Identities = 103/405 (25%), Positives = 193/405 (47%), Gaps = 7/405 (1%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 +++G++ + G P +++ DP++++ +L + + F Q L + L+ E E+ Sbjct: 66 EKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+PAF K K M+P+ S C + ++ A+ +++ F T DV Sbjct: 126 WKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQE--AENSKSINLKDFFGAYTMDV 183 Query: 723 ISRTAFGSNFQ-----EGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDR 887 I+ T FG N + + ++ L + F L + P + + Sbjct: 184 ITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPK 243 Query: 888 EIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFY 1067 ++ L+ I + + + + K++ LS +++ + + Sbjct: 244 DVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIII 303 Query: 1068 FAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSRLKIVTMIFYEV 1244 FA +TTS L + + L+ HP+ Q+K +EE+ P +++L +++ + M+ E Sbjct: 304 FAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNET 363 Query: 1245 LRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADG 1424 LRL+P ++ +TR K +E+ G+ P G+ +M+PI +HHDP W + +F PERF+ Sbjct: 364 LRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPERFSKK 422 Query: 1425 ISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 ++ + PFG GPR CIG FAL K+A+ LQ FSF+ Sbjct: 423 NKDSIDL-YRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 466
>Q27514:C13A5_CAEEL Putative cytochrome P450 CYP13A5 - Caenorhabditis elegans| Length = 520 Score = 152 bits (383), Expect = 6e-36 Identities = 111/433 (25%), Positives = 202/433 (46%), Gaps = 33/433 (7%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRI----GRLLANGLANHE 533 KE+G + G ++V +PE V E+ +F +F +++ I + L + + Sbjct: 62 KEYGPIYGITEGVEKTLIVSNPEFVHEVFVKQFDNFYGRKTNPIQGDPNKNKRAHLVSAQ 121 Query: 534 GEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLT 713 G +W + R + +P F ++ +++++ E++ +++ SA+G VD+ +Q T Sbjct: 122 GHRWKRLRTLSSPTFSNKNLRKIMSTVEETVVELMRHLDDA-SAKGKA-VDLLDYYQEFT 179 Query: 714 GDVISRTAFGSN----------------FQEGMK-------IFQLQGELSERLIQAFQTL 824 D+I R A G F++G K IF + G + F ++ Sbjct: 180 LDIIGRIAMGQTESLMFRNPMLPKVKGIFKDGRKLPFLVSGIFPIAGTMFREFFMRFPSI 239 Query: 825 FIPGYWFFPTKNNRRMRAIDREIRMILRGI--IGKKERAIKNXXXXXXXXXXXXXXSNM- 995 P + T + +++ GI G+ + I S + Sbjct: 240 Q-PAFDIMSTVEKALNKRLEQRAADEKAGIEPSGEPQDFIDLFLDARANVDFFEEESALG 298 Query: 996 --QQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLH 1169 + K + L+ ++II + +F AG +TT++ L+++ +L+ HPE Q+K +EEV Sbjct: 299 FAKTEIAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDR 358 Query: 1170 YFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFL-TRRTYKAMELGGIKYPAGVNLMLP 1346 F+ +S+LK + + E LR+YP + + R+ K + G++ G N+ + Sbjct: 359 ECPNPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMKETNVLGVQIEKGTNVQVD 418 Query: 1347 ILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMA 1526 +H+DP +WG+DA EF PER+ G + PFG GPRICIG A+ E KM Sbjct: 419 TWTLHYDPKVWGEDANEFRPERWESG-DELFYAKGGYLPFGMGPRICIGMRLAMMEKKML 477 Query: 1527 LSTILQRFSFELS 1565 L+ IL++++FE S Sbjct: 478 LTHILKKYTFETS 490
>P33274:CP4F1_RAT Cytochrome P450 4F1 - Rattus norvegicus (Rat)| Length = 524 Score = 151 bits (382), Expect = 8e-36 Identities = 128/450 (28%), Positives = 201/450 (44%), Gaps = 31/450 (6%) Frame = +3 Query: 294 RSQPMPPGSHHIAPRV---------LPMFTNAIKEHGKVSFTWFGP-TPRVMVPDPELVR 443 R P PP + + V L T + + + W GP P + + ++VR Sbjct: 49 RGFPQPPKRNWLMGHVGMVTPTEQGLKELTRLVGTYPQGFLMWIGPMVPVITLCHSDIVR 108 Query: 444 EILSNKFGHFGKQRS--TRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFS 617 IL+ K T + L +GL G+KW++HRR+L PAFH +K + +F+ Sbjct: 109 SILNASAAVALKDVIFYTILKPWLGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFN 168 Query: 618 ACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG--SNFQEGMK-----IFQ 776 M +W+ +S +G +D+ +T D + + F SN QE I + Sbjct: 169 DSTNIMHAKWKRLIS-EGSSRLDMFEHVSLMTLDSLQKCVFSFDSNCQEKSSEYIAAILE 227 Query: 777 LQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXX 956 L +++R Q L + T + R + +I ++ R + + Sbjct: 228 LSALVAKR---HQQPLLFMDLLYNLTPDGMRFHKACNLVHEFTDAVIRERRRTLPDQGLD 284 Query: 957 XXXXXXXXXXSN--------MQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTL 1112 + + +GK LS EDI E F F G +TT+ L+W L Sbjct: 285 EFLKSKAKSKTLDFIDVLLLTKDEDGKE---LSDEDIRAEADTFMFEGHDTTASGLSWIL 341 Query: 1113 IVLSMHPEWQEKAREEVLHYFGRTTPD---FESLSRLKIVTMIFYEVLRLYPPITFLTRR 1283 L+ PE+QE+ R+EV P+ ++ L++L +TM E LRL+PP+T ++R Sbjct: 342 YNLANDPEYQERCRQEVQELLRDRDPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRC 401 Query: 1284 TYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFF 1460 + + L G P G+ ++ I IHH+P +W D +NP RF D + P AF Sbjct: 402 CTQDILLPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYNPFRF-DPENIKDSSPLAFI 459 Query: 1461 PFGGGPRICIGQNFALQEAKMALSTILQRF 1550 PF GPR CIGQ FA+ E K+AL+ L RF Sbjct: 460 PFSAGPRNCIGQTFAMSEMKVALALTLLRF 489
>P10611:CP4A4_RABIT Cytochrome P450 4A4 precursor - Oryctolagus cuniculus (Rabbit)| Length = 510 Score = 151 bits (381), Expect = 1e-35 Identities = 122/437 (27%), Positives = 207/437 (47%), Gaps = 22/437 (5%) Frame = +3 Query: 399 GPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN----GLANHEGEKWAKHRRIL 566 G R++V DP+ ++ IL ++ R +L+ GL +G+ W +HRR+L Sbjct: 92 GNKARLLVYDPDYLKVILGRS-----DPKAPRNYKLMTPWIGYGLLLLDGQTWFQHRRML 146 Query: 567 NPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQN---LTGDVISRTA 737 PAFH++ +K + + + M+ RWE +S E+ FQ+ +T D I + A Sbjct: 147 TPAFHYDILKPYVGLMVDSVQIMLDRWEQLISQDSSLEI-----FQHVSLMTLDTIMKCA 201 Query: 738 FGSNFQEGMKI-------FQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRM--RAIDRE 890 F ++Q +++ Q +L+ + + +F + + R+ RA Sbjct: 202 F--SYQGSVQLDRNSHSYIQAINDLNNLVFYRARNVFHQSDFLYRLSPEGRLFHRACQLA 259 Query: 891 IRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNM----QQSNGKANLGLSIEDIIQECK 1058 R I +K + + ++ + NG + LS +D+ E Sbjct: 260 HEHTDRVIQQRKAQLQQEGELEKVRRKRRLDFLDVLLFAKMENGSS---LSDQDLRAEVD 316 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIF 1235 F F G +TT+ ++W L+ HPE Q + REE+ G + +E L ++ TM Sbjct: 317 TFMFEGHDTTASGVSWIFYALATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCI 376 Query: 1236 YEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 E LRLYPP+ +TR+ K + G P GV L L I +H++P +W ++ F+P R Sbjct: 377 KEALRLYPPVPSVTRQLSKPVTFPDGRSLPKGVILFLSIYGLHYNPKVW-QNPEVFDPFR 435 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYT 1592 FA ++A AF PF GG R CIG+ FA++E K+A++ L RF P+ I P Sbjct: 436 FAP---DSAYHSHAFLPFSGGARNCIGKQFAMRELKVAVALTLVRFELLPDPTRIPIPIA 492 Query: 1593 VITLQPQHGAQIRLKKI 1643 + L+ ++G +RL+K+ Sbjct: 493 RVVLKSKNGIHLRLRKL 509
>P05183:CP3A2_RAT Cytochrome P450 3A2 - Rattus norvegicus (Rat)| Length = 504 Score = 151 bits (381), Expect = 1e-35 Identities = 111/406 (27%), Positives = 195/406 (48%), Gaps = 8/406 (1%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK+ + G TP + D E+++ +L + F F +R ++ ++ + E+ Sbjct: 66 KKYGKIWGLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVSVAKDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W ++R +L+P F ++K M P+ + ++ + A+ V + F + DV Sbjct: 126 WKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQE--AETGKPVTMKKVFGAYSMDV 183 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSERLIQA--FQTLFIPGYWF---FPTKNNRRMRAIDR 887 I+ T+FG N E +++L++ F LF+ F P + + Sbjct: 184 ITSTSFGVNVDSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEMLNICMFPK 243 Query: 888 EIRMILRGIIGK-KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLF 1064 + + + + KE + + ++ + ++ LS +II + +F Sbjct: 244 DSIAFFQKFVHRIKETRLDSKHKHRVDFLQLMLNAHNNSKDEVSHKALSDVEIIAQSVIF 303 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIFYE 1241 FAG ETTS L++ L L+ HP+ Q+K +EE+ + P ++ + ++ + M+ E Sbjct: 304 IFAGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPSKAPPTYDIVMEMEYLDMVLNE 363 Query: 1242 VLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFAD 1421 LRLYP L R K +EL G+ P G + +P +HHDP W K EF+PERF+ Sbjct: 364 TLRLYPIGNRLERVCKKDIELDGLFIPKGSVVTIPTYALHHDPQHWPKP-EEFHPERFSK 422 Query: 1422 GISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 + + P + PFG GPR CIG FAL K+AL+ +LQ FSF+ Sbjct: 423 E-NKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQ 467
>Q9JMA7:CP341_MOUSE Cytochrome P450 3A41 - Mus musculus (Mouse)| Length = 504 Score = 151 bits (381), Expect = 1e-35 Identities = 108/409 (26%), Positives = 194/409 (47%), Gaps = 11/409 (2%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 +++GK + G P ++ DPE+++ +L + F F +R +++ ++ + E+ Sbjct: 66 EKYGKTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITR-WENSMSAQGLCEVDVCPEFQNLTGD 719 W ++R +L+P F K+K M PV + ++ + + + + DV + D Sbjct: 126 WKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSI---D 182 Query: 720 VISRTAFGSNFQ-----EGMKIFQLQGELSERLIQ--AFQTLFIPGYWFFPTKNNRRMRA 878 VI+ T+FG N E + + +G L F + P + P + Sbjct: 183 VITSTSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFP--FLTPVYEMLNICM 240 Query: 879 IDREIRMILRGIIGK-KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQEC 1055 ++ + + + KE + + ++ + ++ LS +I + Sbjct: 241 FPKDSIEFFKKFVNRMKESRLDSKQKHRVDFLQLMMNAHNNSKDKDSHKALSDMEITAQS 300 Query: 1056 KLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMI 1232 +F FAG ETTS L++TL L+ HP+ Q+K +EE+ + P ++++ ++ + M+ Sbjct: 301 IVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMV 360 Query: 1233 FYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 E LRLYP L R K +EL G+ P G +M+P +HHDP W + EF PER Sbjct: 361 LNETLRLYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHW-PEPEEFQPER 419 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 F+ + + P + PFG GPR CIG FA K+AL+ ++Q FSF+ Sbjct: 420 FSKE-NKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQ 467
>Q08477:CP4F3_HUMAN Cytochrome P450 4F3 - Homo sapiens (Human)| Length = 520 Score = 150 bits (379), Expect = 2e-35 Identities = 107/364 (29%), Positives = 176/364 (48%), Gaps = 16/364 (4%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 L +GL GEKW++HRR+L PAFH +K + +F+ M +W+ ++++G +D Sbjct: 132 LGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQ-LLASEGSARLD 190 Query: 687 VCPEFQNLTGDVISRTAFG--SNFQEGMK-----IFQLQGELSERLIQAFQTLFIPGYWF 845 + +T D + + F S+ QE I +L +++R Q L + + Sbjct: 191 MFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKR---HQQILLYIDFLY 247 Query: 846 FPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSN-----MQQSNG 1010 + T + +R R R + +I ++ R + + + + S Sbjct: 248 YLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD 307 Query: 1011 KANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP 1190 + LS EDI E F F G +TT+ L+W L L+ HPE+QE+ R+EV P Sbjct: 308 EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREP 367 Query: 1191 ---DFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFI 1358 +++ L++L +TM E LRL+PP+ ++R + + L G P G+ ++ + Sbjct: 368 KEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGT 427 Query: 1359 HHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTI 1538 HH+P +W D ++P RF D + + P AF PF GPR CIGQ FA+ E K+ L Sbjct: 428 HHNPAVW-PDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLT 485 Query: 1539 LQRF 1550 L RF Sbjct: 486 LLRF 489
>P14579:CP4A5_RABIT Cytochrome P450 4A5 precursor - Oryctolagus cuniculus (Rabbit)| Length = 511 Score = 150 bits (379), Expect = 2e-35 Identities = 115/432 (26%), Positives = 194/432 (44%), Gaps = 15/432 (3%) Frame = +3 Query: 393 WFGPTP-RVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILN 569 W G RV + DP+ ++ IL + T + + GL G+ W +HRR+L Sbjct: 89 WIGGNKVRVQLYDPDYMKVILGRSDPK-SRGSYTFVAPWIGYGLLLLNGQPWFQHRRMLT 147 Query: 570 PAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAF--- 740 PAFH++ +K + + + M+ +WE +S ++V + +T D I + AF Sbjct: 148 PAFHYDILKPYVGLMVDSVQIMLDKWEQLVSQDS--SLEVFQDISLMTLDTIMKCAFSYQ 205 Query: 741 GS---NFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMR------AIDREI 893 GS + + Q G+L+ + + +F + R+ A + Sbjct: 206 GSVQLDSRNSQSYIQAVGDLNNLVFARVRNIFHQSDTIYRLSPEGRLSHRACQLAHEHTD 265 Query: 894 RMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFA 1073 R+I + ++ + NG + LS +D+ E F F Sbjct: 266 RVIQQRKAQLQQEGELEKVRRKRRLDFLDVLLFAKMENGSS---LSDQDLRAEVDTFMFE 322 Query: 1074 GMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIFYEVLR 1250 G +TT+ ++W L+ HPE Q + REE+ G + +E L ++ TM E +R Sbjct: 323 GHDTTASGVSWIFYALATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEAMR 382 Query: 1251 LYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGI 1427 LYPP+ ++R + G P G + L I +HH+P++W + F+P RF G Sbjct: 383 LYPPVPAISRDLSSPVTFPDGRSLPKGFTVTLSIYGLHHNPNVW-PNPEVFDPGRFTPG- 440 Query: 1428 SNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQ 1607 +A+ AF PF GG R CIG+ FA+ E K+A++ L RF P+ I P + L+ Sbjct: 441 --SARHSHAFLPFSGGARNCIGKQFAMNELKVAVALTLVRFELLPDPTRIPKPTARLVLK 498 Query: 1608 PQHGAQIRLKKI 1643 +G +RL+K+ Sbjct: 499 SNNGIHLRLRKL 510
>Q27513:C13A4_CAEEL Putative cytochrome P450 CYP13A4 - Caenorhabditis elegans| Length = 520 Score = 149 bits (377), Expect = 3e-35 Identities = 116/437 (26%), Positives = 205/437 (46%), Gaps = 37/437 (8%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF-GKQRSTRIGRLLANGLAN---HE 533 K++G + G ++V +PE V E+ +F +F G++ + G N A+ + Sbjct: 62 KKYGSIYGITEGVEKTLVVSNPEFVHEVFVKQFDNFYGRKTNPIQGDPNKNKRAHLVLAQ 121 Query: 534 GEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLT 713 G +W + R + +P F ++ +++++ E++ R + SA+G VD+ +Q T Sbjct: 122 GHRWKRLRTLASPTFSNKSLRKIMSTVEETVVELM-RHLDEASAKGKA-VDLLDYYQEFT 179 Query: 714 GDVISRTAFGSN----------------FQEGMK-------IFQLQGELSERLIQAFQTL 824 D+I R A G F++G K +F + G L +L F Sbjct: 180 LDIIGRIAMGQTESLMFRNPMLPKVKEIFKKGGKMPFLIAGVFPIAGTLMRQLFMKFPK- 238 Query: 825 FIPGYWFFPTKNNRRMRAIDREIRMILRGI--IGKKERAIKNXXXXXXXXXXXXXXSNMQ 998 F P + T + +++ GI G+ + I S + Sbjct: 239 FSPAFGIMNTMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDARANVDFIEEESTLG 298 Query: 999 QSNG---KANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLH 1169 + K + L+ ++II + +F AG +TT++ L+++ +L+ HPE Q+K +EEV Sbjct: 299 FAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEV-- 356 Query: 1170 YFGRTTPD----FESLSRLKIVTMIFYEVLRLYPPITFL-TRRTYKAMELGGIKYPAGVN 1334 R PD F+ +S+LK + + E LR+YP + + R+ K + G++ G N Sbjct: 357 --DRECPDPEVTFDQISKLKYMECVVKEALRMYPLASLVHNRKCMKKTNVLGVEIDEGTN 414 Query: 1335 LMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQE 1514 + + +H+DP +WG DA EF PER+ G + PFG GPRICIG A+ E Sbjct: 415 VQVDTWTLHYDPKVWGDDASEFKPERWETG-DELFYAKGGYLPFGMGPRICIGMRLAMME 473 Query: 1515 AKMALSTILQRFSFELS 1565 K+ L+ IL++++F+ S Sbjct: 474 EKLLLTHILKKYTFDTS 490
>Q86W10:CP4Z1_HUMAN Cytochrome P450 4Z1 - Homo sapiens (Human)| Length = 505 Score = 149 bits (376), Expect = 4e-35 Identities = 124/438 (28%), Positives = 204/438 (46%), Gaps = 21/438 (4%) Frame = +3 Query: 393 WFGP-TPRVMVPDPELVREILSN---KFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRR 560 W GP T V DP+ + +L K K + +GR GL +G KW KHR+ Sbjct: 83 WVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGR----GLVTLDGSKWKKHRQ 138 Query: 561 ILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQN---LTGDVISR 731 I+ P F+ +K + + S M+ +WE ++ E+ FQ+ +T D I + Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLEL-----FQHVSLMTLDSIMK 193 Query: 732 TAFG--------SNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDR 887 AF S +K ++S + + F L F + + ++ Sbjct: 194 CAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNF--LHHNDLVFKFSSQGQIFSKFNQ 251 Query: 888 EIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANL-GLSIEDIIQECKLF 1064 E+ +I ++ ++K+ ++ S N S D+ E K F Sbjct: 252 ELHQFTEKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTF 311 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIFYE 1241 FAG +TTS ++W L L+ +PE Q++ R+E+ G ++ +E LS++ TM E Sbjct: 312 MFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKE 371 Query: 1242 VLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFA 1418 LRLY P+ ++R K + G PAG+ + + I +HH+P W +D + FNP RF+ Sbjct: 372 CLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFW-EDPQVFNPLRFS 430 Query: 1419 DGISNAAK-RPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTV 1595 N+ K P AF PF G R CIGQ+FA+ E K+A++ L R F+L+P + P V Sbjct: 431 R--ENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLR--FKLAPDHSRPPQPV 486 Query: 1596 --ITLQPQHGAQIRLKKI 1643 + L+ ++G + KK+ Sbjct: 487 RQVVLKSKNGIHVFAKKV 504
>P20816:CP4A2_RAT Cytochrome P450 4A2 precursor - Rattus norvegicus (Rat)| Length = 504 Score = 149 bits (376), Expect = 4e-35 Identities = 115/465 (24%), Positives = 205/465 (44%), Gaps = 24/465 (5%) Frame = +3 Query: 321 HHIAPRVLPMFTNAIKEHGKVSFTWF-GPTPRVMVPDPELVREILSNKFGHFGKQRSTRI 497 H++ R +++ W G T RV++ DP+ V+ +L G + + Sbjct: 62 HNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVL----GRSDPKPYQSL 117 Query: 498 GRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLC 677 + GL G+KW +HRR+L PAFH++ +K + + + M+ +WE Sbjct: 118 APWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPL 177 Query: 678 EVDVCPEFQNLTGDVISRTAFGSNFQEGMKI-----FQLQGELSERLIQAFQTLFIPGYW 842 E+ L D + + AF + + + +L+ + ++ F Sbjct: 178 EIFHYVSLMTL--DTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSI 235 Query: 843 FFPTKNNRRM-RAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKAN 1019 + ++ R+ R + G+I ++ ++N +Q++ K + Sbjct: 236 IYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNE-------------EELQKARKKRH 282 Query: 1020 L---------------GLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAR 1154 L LS ED+ E F F G +TT+ ++W L+ HPE QE+ R Sbjct: 283 LDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCR 342 Query: 1155 EEVLHYFGR-TTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAG 1328 EEV G T+ ++ L ++ TM E LRLY P+ ++R + G P G Sbjct: 343 EEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKG 402 Query: 1329 VNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFAL 1508 + + + I +HH+P W + + F+P RF+ ++ + A+ PF GG R CIG+ FA+ Sbjct: 403 IRVTILIYGLHHNPSYW-PNPKVFDPSRFSP---DSPRHSHAYLPFSGGARNCIGKQFAM 458 Query: 1509 QEAKMALSTILQRFSFELSPSYIHAPYTVITLQPQHGAQIRLKKI 1643 E K+A++ L RF P+ I P + L+ ++G +RLKK+ Sbjct: 459 NELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKL 503
>P51538:CP3A9_RAT Cytochrome P450 3A9 - Rattus norvegicus (Rat)| Length = 503 Score = 148 bits (374), Expect = 7e-35 Identities = 113/408 (27%), Positives = 197/408 (48%), Gaps = 10/408 (2%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK+ + G P + + DP++++ +L + + F +R+ +L ++ E E+ Sbjct: 66 KKYGKLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVGILKKAISISEDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRW-ENSMSAQGLCEVDVCPEFQNLTGD 719 W + R +L+P F K+K M P+ + + ++ + S + D+ F + D Sbjct: 126 WKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDI---FGAYSMD 182 Query: 720 VISRTAFGSNFQEGMKIFQLQGELSERLIQ--AFQTLFIPGYWF---FPTKNNRRMRAID 884 VI+ T+FG N E ++L++ F LF+ F P + Sbjct: 183 VITATSFGVNVDSLNNPQDPFVEKVKKLLKFDIFDPLFLSVTLFPFLTPLFEALNVSMFP 242 Query: 885 REIRMILRGIIGK-KERAIKNXXXXXXXXXXXXXXSNMQQSNGK-ANLGLSIEDIIQECK 1058 R++ + + + KE +K N Q S K ++ LS +I+ + Sbjct: 243 RDVIDFFKTSVERMKENRMKEKEKQRMDFLQLMI--NSQNSKVKDSHKALSDVEIVAQSV 300 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIF 1235 +F FAG ETTS L++ L +L++HP+ Q+K ++E+ + +++L +++ + M+ Sbjct: 301 IFIFAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVV 360 Query: 1236 YEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 E LRLYP L R +E+ G+ P G +M+P +H DP W + EF PERF Sbjct: 361 NETLRLYPIAGRLERVCKTDVEINGVFIPKGTVVMIPTFALHKDPHYW-PEPEEFRPERF 419 Query: 1416 ADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 + + P + PFG GPR CIG FAL K+AL +LQ FSF+ Sbjct: 420 SKKNQDNIN-PYMYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFSFQ 466
>Q9VFJ0:CP131_DROME Probable cytochrome P450 313a1 - Drosophila melanogaster (Fruit fly)| Length = 492 Score = 148 bits (374), Expect = 7e-35 Identities = 112/435 (25%), Positives = 184/435 (42%), Gaps = 22/435 (5%) Frame = +3 Query: 336 RVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTR-IGRLLA 512 R L T + ++G TW GP P ++ DP++V +I S+ H Q I + Sbjct: 53 RKLSFRTKYLNKYGSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMG 112 Query: 513 NGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVC 692 NGL + W R+ NP+F + + +F A + ++ + + E+DV Sbjct: 113 NGLLGKQDPHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKG---EIDVV 169 Query: 693 PEFQNLTGDVISRTAFGS------NFQEGMKIFQLQGELSERLIQAFQTLF-------IP 833 PE + + ++T GS +F+ G + + +S + L I Sbjct: 170 PEMLRWSFKIAAQTTMGSEVKHDEHFKNGSLVESFESLISHSTLNILMPLVQNRMISKIC 229 Query: 834 GYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGK 1013 GY N R I+ +L ++ KK + + + Sbjct: 230 GYDKLRADNFSR-------IQKMLDNVVNKKVNPLPKTDSDPESNIVINRAMELYRKGD- 281 Query: 1014 ANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV------LHYF 1175 ++ D+ EC + AG +T+++ + L +L+ HPE QE EE+ +F Sbjct: 282 ----ITYMDVKSECCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHF 337 Query: 1176 GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELG-GIKYPAGVNLMLPIL 1352 G T PD + L L+ + E LRL P I R T + L G+ P GV + + + Sbjct: 338 GITYPDMQKLDYLE---RVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMF 394 Query: 1353 FIHHDPDIWGKDAREFNPERF-ADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMAL 1529 H +P++WG DA FNP+ F A+ + K P A+ PF G R CIG +A+ +K AL Sbjct: 395 HTHRNPEVWGPDADNFNPDNFLAENMEQ--KHPYAYIPFARGKRNCIGSKYAMMSSKFAL 452 Query: 1530 STILQRFSFELSPSY 1574 IL+ + S Y Sbjct: 453 CRILRNYKISTSTLY 467
>Q09653:C13AA_CAEEL Putative cytochrome P450 CYP13A10 - Caenorhabditis elegans| Length = 519 Score = 148 bits (374), Expect = 7e-35 Identities = 109/424 (25%), Positives = 191/424 (45%), Gaps = 36/424 (8%) Frame = +3 Query: 399 GPTPRVMVPDPELVREILSNKFGHFGKQRSTRIG----RLLANGLANHEGEKWAKHRRIL 566 G ++V D ++VR+I ++ +F ++ I + L + +G +W + R I Sbjct: 73 GTIKTLIVSDIDIVRQIFVEQYDNFYGRKLNPIQGDPEKDERTNLFSAQGFRWKRLRAIS 132 Query: 567 NPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGS 746 +P F + ++++ E++ E S ++D+ +Q T D I R A G Sbjct: 133 SPTFSNNSLRKINVTVEDSAMELLRHIEEQTSEGQ--QIDMLQFYQEFTMDTIGRIAMGQ 190 Query: 747 N----------------FQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRA 878 F + K L G + L Q F+ + FP Sbjct: 191 TDSQMFKNPLLKFVRAIFGDNRKHIPLIGGVFPTLAQVFRFFMLK----FPLLGAANFIH 246 Query: 879 IDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXX--------SNMQQSNGK------- 1013 +++ + ++ I ++E KN + Q++NG Sbjct: 247 VNKTVVTAVQNRIDQRENDRKNGIEIGEPQDFIDLFLEARADDVEHFQENNGDFSKTSSY 306 Query: 1014 ANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD 1193 N L+ ++I+ +C +F AG +TT++ L++T +L+ HPE Q+K +EE+ + Sbjct: 307 GNRQLTTQEIVGQCLVFLIAGFDTTALSLSYTTFLLATHPEVQKKLQEEIERECIEPSIS 366 Query: 1194 FESLSRLKIVTMIFYEVLRLYPPITFL-TRRTYKAMELGGIKYPAGVNLMLPILFIHHDP 1370 F+ LS+LK + I E LRLYP T +RR +A +LG ++ G + + +H D Sbjct: 367 FDHLSKLKYMDCIIKETLRLYPLGTMANSRRCMRATKLGNVEVEVGTMVQVDTWSLHTDT 426 Query: 1371 DIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 IWG DA+EF PER+ D + + + FG GPR C+G A E KM L+ IL+++ Sbjct: 427 KIWGDDAKEFKPERWLDPNCDQVFQKGGYISFGLGPRQCVGMRLAYMEEKMLLAHILRKY 486 Query: 1551 SFEL 1562 +FE+ Sbjct: 487 TFEV 490
>O35728:CP4AE_MOUSE Cytochrome P450 4A14 precursor - Mus musculus (Mouse)| Length = 507 Score = 148 bits (373), Expect = 9e-35 Identities = 119/435 (27%), Positives = 195/435 (44%), Gaps = 20/435 (4%) Frame = +3 Query: 399 GPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN----GLANHEGEKWAKHRRIL 566 G RV++ DP+ V+ +L +++ I + A GL G+KW +HRR+L Sbjct: 89 GSNIRVLLYDPDYVKVVLGRS-----DPKASGIYQFFAPWIGYGLLLLNGKKWFQHRRML 143 Query: 567 NPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAF-- 740 PAFH++ +K + + + M+ +WE E+ C L D + + AF Sbjct: 144 TPAFHYDILKPYVKIMADSVNIMLDKWEKLDGQDHPLEIFHCVSLMTL--DTVMKCAFSY 201 Query: 741 -GS-NFQEGMKIFQLQGE-LSERLIQAFQTLFIPGYWFFPTKNNRRM---------RAID 884 GS E K++ E L+ + F + ++ R+ D Sbjct: 202 QGSVQLDENSKLYTKAVEDLNNLTFFRLRNAFYKYNIIYNMSSDGRLSHHACQIAHEHTD 261 Query: 885 REIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLF 1064 I+M + + +E K + M+ N LS ED+ E F Sbjct: 262 GVIKM-RKSQLQNEEELQKARKKRHLDFLDILLFARMEDRNS-----LSDEDLRAEVDTF 315 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIFYE 1241 F G +TT+ ++W L+ HPE Q++ REEV G T+ ++ L ++ TM E Sbjct: 316 MFEGHDTTASGISWIFYALATHPEHQQRCREEVQSILGDGTSVTWDHLGQMPYTTMCIKE 375 Query: 1242 VLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFA 1418 LRLYPP+ ++R + G P G+ + I +HH+P W + + F+P RFA Sbjct: 376 ALRLYPPVISVSRELSSPVTFPDGRSIPKGITATISIYGLHHNPRFW-PNPKVFDPSRFA 434 Query: 1419 DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVI 1598 S+ + A+ PF GG R CIG+ FA+ E K+A++ L RF P+ I P + Sbjct: 435 PDSSHHSH---AYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPIARL 491 Query: 1599 TLQPQHGAQIRLKKI 1643 L+ ++G + LKK+ Sbjct: 492 VLKSKNGIHLCLKKL 506
>P24463:CP3AC_CANFA Cytochrome P450 3A12 - Canis familiaris (Dog)| Length = 503 Score = 147 bits (372), Expect = 1e-34 Identities = 108/415 (26%), Positives = 193/415 (46%), Gaps = 18/415 (4%) Frame = +3 Query: 369 EHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEKW 545 ++G++ + G P + + DP++++ +L + + F +R+ + + ++ E E+W Sbjct: 67 KYGRMWGFYDGRQPVLAITDPDMIKTVLVKECYSVFTNRRTLGPVGFMKSAISLSEDEEW 126 Query: 546 AKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVI 725 + R +L+P F K+K M P+ + ++ A+ +++ F + DVI Sbjct: 127 KRMRTLLSPTFTTGKLKEMFPIIGQYGDVLVNNLRKE--AEKGKAINLKDVFGAYSMDVI 184 Query: 726 SRTAFGSNFQEGMKIFQLQGELSERLIQA-------FQTLFIP---------GYWFFPTK 857 + T+FG N E +++L++ F L P W FP K Sbjct: 185 TSTSFGVNIDSLNHPQDPFVENTKKLLKFDFLDPFFFSILLFPFLTPVFEILNIWLFPKK 244 Query: 858 NNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIE 1037 R + + KE +K+ S + + LS Sbjct: 245 VTDFFR----------KSVERMKESRLKDKQKHRVDFLQLMINSQNSKEMD-THKALSDL 293 Query: 1038 DIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRL 1214 +++ + +F FAG ETTS L++ + L+ HP+ Q+K +EE+ F + P +++L ++ Sbjct: 294 ELVAQSIIFIFAGYETTSTSLSFLMYELATHPDVQQKLQEEIDATFPNKALPTYDALVQM 353 Query: 1215 KIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAR 1394 + + M+ E LRLYP L R K +E+ G+ P G +M+P +H D +W + Sbjct: 354 EYLDMVLNETLRLYPIAGRLERVCKKDVEISGVFIPKGTVVMVPTFTLHRDQSLW-PEPE 412 Query: 1395 EFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 EF PERF+ ++ P + PFG GPR CIG FA+ K+AL +LQ FSF+ Sbjct: 413 EFRPERFSRKNKDSI-NPYTYLPFGTGPRNCIGMRFAIMNMKLALVRVLQNFSFK 466
>P08684:CP3A4_HUMAN Cytochrome P450 3A4 - Homo sapiens (Human)| Length = 503 Score = 147 bits (372), Expect = 1e-34 Identities = 105/408 (25%), Positives = 193/408 (47%), Gaps = 10/408 (2%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GKV + G P + + DP++++ +L + + F +R + + ++ E E+ Sbjct: 66 KKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+P F K+K M+P+ + + ++ A+ V + F + DV Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRE--AETGKPVTLKDVFGAYSMDV 183 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWF--------FPTKNNRRMRA 878 I+ T+FG N + Q E + + F+ ++ P + Sbjct: 184 ITSTSFGVNIDS---LNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICV 240 Query: 879 IDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECK 1058 RE+ LR + + + + + +++ LS +++ + Sbjct: 241 FPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSI 300 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIF 1235 +F FAG ETTS +L++ + L+ HP+ Q+K +EE+ + P ++++ +++ + M+ Sbjct: 301 IFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVV 360 Query: 1236 YEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 E LRL+P L R K +E+ G+ P GV +M+P +H DP W + +F PERF Sbjct: 361 NETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPERF 419 Query: 1416 ADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 + + P + PFG GPR CIG FAL K+AL +LQ FSF+ Sbjct: 420 SKKNKDNID-PYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>Q27517:C13A3_CAEEL Putative cytochrome P450 CYP13A3 - Caenorhabditis elegans| Length = 520 Score = 147 bits (371), Expect = 1e-34 Identities = 125/467 (26%), Positives = 206/467 (44%), Gaps = 43/467 (9%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRI----GRLLANGLANHE 533 KE+G + G ++V DPE V E+ +F +F ++ + + L + Sbjct: 62 KEYGPMYGFTDGVEKTLVVSDPEFVHEVFVKQFDNFYARKQNPLQGDPDKDPRIHLVTSQ 121 Query: 534 GEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLT 713 G +W + R + +P F ++ ++++ EM+ E + G +D+ +Q T Sbjct: 122 GHRWKRLRTLASPTFSNKSLRKIFSTVEESVAEMMRHLEKGTA--GGKTIDILEYYQEFT 179 Query: 714 GDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQT-----LFIPGY---------WFF- 848 D+I + A G Q G +F + +++ F T I G WFF Sbjct: 180 MDIIGKIAMG---QSGSMMF--ENPWLDKIRAIFNTRGNIIFIICGIVPFTGSIFRWFFS 234 Query: 849 --PTKNNRRMRAIDREIRMILR----------GIIGKKERAIKNXXXXXXXXXXXXXXSN 992 PT EI + R GI E ++ Sbjct: 235 KVPTAQTVTSLMHTLEIALTKRVEQRAADEKAGIESSGEP--QDFIDLFLDVQADTDFLE 292 Query: 993 MQQSNG-------KANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKA 1151 + NG K + L+ ++II + +F AG +TT++ L+++ +L+ HPE Q+K Sbjct: 293 DETKNGFARSQIVKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKL 352 Query: 1152 REEVLHYFGRTTPD----FESLSRLKIVTMIFYEVLRLYPPITFL-TRRTYKAMELGGIK 1316 +EEV R PD F+ LS+LK + + E LRLYP + + R+ K+ + G+K Sbjct: 353 QEEV----DRECPDPEVTFDQLSKLKYMECVIKETLRLYPLASIVHNRKCMKSTTVLGMK 408 Query: 1317 YPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQ 1496 G N+ +H+DP WG++A EF PER+ G A + A+ PFG GPRICIG Sbjct: 409 IEEGTNVQADTWTLHYDPKFWGENANEFKPERWESGDEQAVAK-GAYLPFGLGPRICIGM 467 Query: 1497 NFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQPQHGAQIRLK 1637 A E KM L+ IL+++S E + H P ++ + + LK Sbjct: 468 RLAYMEEKMLLAQILKKYSLE-TTFETHIPLKLVGIATTAPTNVHLK 513
>O70537:CP3AV_MESAU Cytochrome P450 3A31 - Mesocricetus auratus (Golden hamster)| Length = 501 Score = 147 bits (370), Expect = 2e-34 Identities = 110/406 (27%), Positives = 194/406 (47%), Gaps = 8/406 (1%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK+ + G P V D E+++ +L + + F +R +++ ++ + E+ Sbjct: 66 KKYGKIWGLFEGQRPLFTVTDTEMIKNVLVKECYSIFTNRRDFGPVGIMSKAVSISKDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+P F K+K M P+ +++ ++ + +G V F + DV Sbjct: 126 WKRIRALLSPTFTSGKLKEMFPIIEQY-GDILVKFLRREAEKGN-PVTTKEVFGAYSMDV 183 Query: 723 ISRTAFGSNFQE--GMKIFQLQGELSERLIQAFQTLFIPGYWF---FPTKNNRRMRAIDR 887 I+ TAFG + K +G R F LF+ F P + + Sbjct: 184 ITSTAFGVSVDSLNNPKDLLWKGRKLLRF-DFFDPLFLSVVLFPFLIPIYEKLNVSMFPK 242 Query: 888 EIRMILRGIIGK-KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLF 1064 + R + K KE + N ++ ++ LS +II + +F Sbjct: 243 DSISFFRKFVDKTKENRLD--YNQKHRVDFLQLMMNSHDNSKDSHKALSDMEIIAQSIIF 300 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV-LHYFGRTTPDFESLSRLKIVTMIFYE 1241 FAG +TTS L++ L +L+ HP+ Q+K +EE+ + + P ++ + ++ + M+ E Sbjct: 301 IFAGYDTTSSTLSFALYLLATHPDVQKKLQEEIDIALPNKARPSYDKVMEMEYLDMVLNE 360 Query: 1242 VLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFAD 1421 LRLYP + L R + +E+ G+ P G +M+P+ +H+DP W + +F PERF+ Sbjct: 361 TLRLYPIGSRLERVCKQDVEMDGVFVPKGSIVMVPVFALHYDPQYW-PEPEKFRPERFSK 419 Query: 1422 GISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 + + P F PFG GPR CIG FAL K+AL+ +LQ FS + Sbjct: 420 E-NKGSIDPYIFLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSLQ 464
>P79102:CP3AS_BOVIN Cytochrome P450 3A28 - Bos taurus (Bovine)| Length = 507 Score = 147 bits (370), Expect = 2e-34 Identities = 116/433 (26%), Positives = 209/433 (48%), Gaps = 13/433 (3%) Frame = +3 Query: 300 QPMPP-GSHHIAPRVLPMFTN-AIKEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGH 470 +P+P GS + +P F N K++GK+ + G P + + DP++++ +L + + Sbjct: 42 RPVPYFGSTMAYHKGIPEFDNQCFKKYGKMWGFYEGRQPMLAITDPDIIKTVLVKECYSV 101 Query: 471 FGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWE 650 F +R ++ ++ E+W + R +L+PAF K+K M P+ + ++ Sbjct: 102 FTNRRIFGPMGIMKYAISLAWDEQWKRIRTLLSPAFTSGKLKEMFPIIGQYGDMLVRNLR 161 Query: 651 NSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTL-- 824 A+ V++ F + DVI+ TAFG N E S+ L++ F+ Sbjct: 162 KE--AEKGNPVNMKDMFGAYSMDVITGTAFGVNIDSLNNPHDPFVEHSKNLLR-FRPFDP 218 Query: 825 FIPGYWFFPTKNN----RRMRAIDRE-IRMILRGIIGKKERAI--KNXXXXXXXXXXXXX 983 FI FP N + + + + + KE + K Sbjct: 219 FILSIILFPFLNPVFEILNITLFPKSTVDFFTKSVKKIKESRLTDKQMNRVDLLQLMINS 278 Query: 984 XSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV 1163 ++ + N KA LS +++ + +F F G ETTS L++ + L+ HP Q+K +EE+ Sbjct: 279 QNSKEIDNHKA---LSDIELVAQSTIFIFGGYETTSSTLSFIIYELTTHPHVQQKLQEEI 335 Query: 1164 LHYF-GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLM 1340 F + P +++L +++ + M+ E LR++P L R K +E+ G+ P G ++ Sbjct: 336 DATFPNKAPPTYDALVQMEYLDMVVNETLRMFPIAGRLERVCKKDVEIHGVTIPKGTTVL 395 Query: 1341 LPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAK 1520 +P+ +H++P++W + EF PERF+ ++ P + PFG GPR C+G FA+ K Sbjct: 396 VPLFVLHNNPELW-PEPEEFRPERFSKNNKDSI-NPYVYLPFGTGPRNCLGMRFAIMNIK 453 Query: 1521 MALSTILQRFSFE 1559 +AL ILQ FSF+ Sbjct: 454 LALVRILQNFSFK 466
>P04800:CP3A1_RAT Cytochrome P450 3A1 - Rattus norvegicus (Rat)| Length = 504 Score = 147 bits (370), Expect = 2e-34 Identities = 107/406 (26%), Positives = 193/406 (47%), Gaps = 8/406 (1%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK+ + G P + D E+++ +L + F F +R ++ ++ + E+ Sbjct: 66 KKYGKIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVSVAKDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W ++R +L+P F ++K M P+ + ++ + A+ V + F + DV Sbjct: 126 WKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQE--AETGKPVTMKKVFGAYSMDV 183 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSERLIQA--FQTLFIPGYWF---FPTKNNRRMRAIDR 887 I+ T+FG N E +++L++ F LF+ F P + + Sbjct: 184 ITSTSFGVNVDSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEMLNICMFPK 243 Query: 888 E-IRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLF 1064 + I + + KE + + ++ + +++ LS +I + +F Sbjct: 244 DSIEFFKKFVYRMKETRLDSVQKHRVDFLQLMMNAHNDSKDKESHTALSDMEITAQSIIF 303 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIFYE 1241 FAG E TS L++ L L+ HP+ Q+K +EE+ + P ++++ ++ + M+ E Sbjct: 304 IFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNE 363 Query: 1242 VLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFAD 1421 LRLYP L R K +E+ G+ P G +M+P +H DP W + EF PERF+ Sbjct: 364 TLRLYPIGNRLERVCKKDVEINGVFMPKGSVVMIPSYALHRDPQHW-PEPEEFRPERFSK 422 Query: 1422 GISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 + + P + PFG GPR CIG FAL K+AL+ +LQ FSF+ Sbjct: 423 E-NKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQ 467
>Q91WL5:CP4AC_MOUSE Cytochrome P450 4A12 - Mus musculus (Mouse)| Length = 508 Score = 146 bits (369), Expect = 3e-34 Identities = 112/433 (25%), Positives = 192/433 (44%), Gaps = 17/433 (3%) Frame = +3 Query: 396 FGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLA----NGLANHEGEKWAKHRRI 563 +G R+ V DP+ ++ IL ++ R LA GL +G+ W +HRR+ Sbjct: 89 WGSKVRIQVYDPDYMKLILGRS-----DPKANGSYRFLAPWIGRGLLLLDGQTWFQHRRM 143 Query: 564 LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG 743 L PAFH++ +K + + M+ +WE + E+ +T D I + AF Sbjct: 144 LTPAFHYDILKPYTEIMADSVRVMLDKWEQIVGQDSTLEI--FRHITLMTLDTIMKCAFS 201 Query: 744 SNFQEGM-----KIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMR------AIDRE 890 + Q +L++ + + +F + +N A D Sbjct: 202 HEGSVQLDRKYKSYIQAVEDLNDLVFSRVRNIFHQNDIIYRVSSNGCKANSACKLAHDHT 261 Query: 891 IRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYF 1070 ++I I ++ + NGK+ LS +D+ E F F Sbjct: 262 DQVIKSRRIQLQDEEELEKLKKKRRLDFLDILLFARMENGKS---LSDKDLRAEVDTFMF 318 Query: 1071 AGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIFYEVL 1247 G +TT+ ++W L+ +PE Q++ R+E+ G T+ + L ++ TM E L Sbjct: 319 EGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLGDGTSITWNDLDKMPYTTMCIKEAL 378 Query: 1248 RLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADG 1424 R+YPP+ ++R + G P G+++ML +HH+P +W + F+P RFA G Sbjct: 379 RIYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVW-PNPEVFDPSRFAPG 437 Query: 1425 ISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITL 1604 S + +F PF GG R CIG+ FA+ E K+A++ L RF P+ + P I L Sbjct: 438 SS---RHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRVPIPIPRIVL 494 Query: 1605 QPQHGAQIRLKKI 1643 + ++G + LKK+ Sbjct: 495 KSKNGIHLHLKKL 507
>Q27519:C13A7_CAEEL Putative cytochrome P450 CYP13A7 - Caenorhabditis elegans| Length = 518 Score = 146 bits (369), Expect = 3e-34 Identities = 117/450 (26%), Positives = 206/450 (45%), Gaps = 41/450 (9%) Frame = +3 Query: 351 FTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRI----GRLLANG 518 F+ K++G V G +++ DPE V E+ +F +F ++ T I + Sbjct: 57 FSEWTKKYGPVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGRKLTAIQGDPNKNKRVP 116 Query: 519 LANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPE 698 L +G +W + R + +P F ++ +++++ E++ E + SA+G +D+ Sbjct: 117 LVAAQGHRWKRLRTLASPTFSNKSLRKIMGTVEESVTELVRSLEKA-SAEGK-TLDMLEY 174 Query: 699 FQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQ-----TLFIPGYWFFPTKNN 863 +Q T D+I + A G K + + +++ F+ I G + F Sbjct: 175 YQEFTMDIIGKMAMGQE-----KSLMFRNPMLDKVKTIFKEGRNNVFMISGIFPFVGIAL 229 Query: 864 RRMRA------IDREIRMILRGIIGKK-------ERA--IKNXXXXXXXXXXXXXXSNMQ 998 R + A + +I+ IL + K+ E+A + S + Sbjct: 230 RNIFAKFPSLQMATDIQSILEKALNKRLEQREADEKAGIEPSGEPQDFIDLFLDARSTVD 289 Query: 999 QSNGKANLGLSIEDIIQECK------------LFYFAGMETTSVLLTWTLIVLSMHPEWQ 1142 G+A + ++++ K +F AG +TT++ L+++ +L+ HPE Q Sbjct: 290 FFEGEAEQDFAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQ 349 Query: 1143 EKAREEVLHYFGRTTPD----FESLSRLKIVTMIFYEVLRLYPPITFL-TRRTYKAMELG 1307 +K +EEV R PD F+ LS+LK + + E LRLYP + + R+ K + Sbjct: 350 KKLQEEV----DRECPDPEVTFDQLSKLKYLECVVKEALRLYPLASLVHNRKCLKTTNVL 405 Query: 1308 GIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRIC 1487 G++ AG N+ + +HHDP +WG D EF PER+ G + PFG GPRIC Sbjct: 406 GMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERWESG-DELFFAKGGYLPFGMGPRIC 464 Query: 1488 IGQNFALQEAKMALSTILQRFSFELSPSYI 1577 IG A+ E KM L+ IL+ ++FE +P + Sbjct: 465 IGMRLAMMEMKMLLTNILKNYTFETTPETV 494
>P20817:CP4AE_RAT Cytochrome P450 4A14 precursor - Rattus norvegicus (Rat)| Length = 507 Score = 146 bits (368), Expect = 3e-34 Identities = 120/472 (25%), Positives = 203/472 (43%), Gaps = 31/472 (6%) Frame = +3 Query: 321 HHIAPRVLPMFTNAIKEHGKVSFTWF-GPTPRVMVPDPELVREILSNKFGHFGKQRSTRI 497 H + R +++ W G RV++ DP+ V+ +L +++ I Sbjct: 62 HDLKDREFQQVLTWVEKFPGACLQWLSGSKTRVLLYDPDYVKVVLGRS-----DPKASGI 116 Query: 498 GRLLAN----GLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSA 665 + LA GL G+KW +HRR+L PAFH+ +K + + + M+ +WE Sbjct: 117 YQFLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYGILKPYVKIMADSVNIMLDKWEKLDDQ 176 Query: 666 QGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQ--TLFIPGY 839 E+ L D + + AF +G + + ++ T F Sbjct: 177 DHPLEIFHYVSLMTL--DTVMKCAFS---HQGSVQLDVNSRSYTKAVEDLNNLTFFRVRS 231 Query: 840 WFFPTKNNRRMRAIDREIRMILR-------GIIGKKERAIKNXXXXXXXXXXXXXXSNMQ 998 F+ M + R R + G+I ++ ++N +Q Sbjct: 232 AFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKMRKAQLQNE-------------EELQ 278 Query: 999 QSNGKANL---------------GLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHP 1133 ++ K +L LS ED+ E F F G +TT+ ++W L+ HP Sbjct: 279 KARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHP 338 Query: 1134 EWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMEL-G 1307 E QE+ REEV G T+ ++ L ++ TM E LRLYPP+ ++R + Sbjct: 339 EHQERCREEVQSILGDGTSVTWDHLDQIPYTTMCIKEALRLYPPVPSVSRELSSPVTFPD 398 Query: 1308 GIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRIC 1487 G P G+ + I +HH+P W + + F+P RF+ ++ + A+ PF GG R C Sbjct: 399 GRSIPKGITTTILIYGLHHNPSYW-PNPKVFDPSRFSP---DSPRHSHAYLPFSGGARNC 454 Query: 1488 IGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQPQHGAQIRLKKI 1643 IG+ FA+ E K+A++ L RF P+ I P + L+ ++G +RLKK+ Sbjct: 455 IGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMARLVLKSKNGIHLRLKKL 506
>P14580:CP4A6_RABIT Cytochrome P450 4A6 precursor - Oryctolagus cuniculus (Rabbit)| Length = 510 Score = 146 bits (368), Expect = 3e-34 Identities = 113/430 (26%), Positives = 191/430 (44%), Gaps = 14/430 (3%) Frame = +3 Query: 396 FGPTPRVMVPDPELVREILSNKFGHFGKQRSTR-IGRLLANGLANHEGEKWAKHRRILNP 572 +G +++ DP+ ++ IL Q S R + + GL G+ W +HRR+L P Sbjct: 91 WGSRAHLLIYDPDYMKVILGRSDPK--AQGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148 Query: 573 AFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNF 752 AFH++ +K + + + + M+ +WE +S ++V + +T D I + AF Sbjct: 149 AFHYDILKPYVGLMADSVQIMLDKWEQLVSQDS--SLEVFQDISLMTLDTIMKCAFSHQG 206 Query: 753 -----QEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMR------AIDREIRM 899 + Q G+L+ + +F + R+ A + R+ Sbjct: 207 SVQLDRNSQSYIQAVGDLNNLFFSRVRNVFHQSDTIYRLSPEGRLSHRACQLAHEHTDRV 266 Query: 900 ILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGM 1079 I + ++ + NG + LS +D+ E F F G Sbjct: 267 IQQRKAQLQQEGELEKVRRKRRLDFLDVLLFAKMENGSS---LSDQDLRAEVDTFMFEGH 323 Query: 1080 ETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIFYEVLRLY 1256 +TT+ ++W L+ HPE Q + REE+ G + +E L ++ TM E LRLY Sbjct: 324 DTTASGISWIFYALATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEALRLY 383 Query: 1257 PPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISN 1433 PP+ + R+ + G P GV + L I +HH+P +W + F+P FA G Sbjct: 384 PPVPGVGRQLSSPVTFPDGRSLPKGVIVTLSIYALHHNPKVW-PNPEVFDPFPFAPG--- 439 Query: 1434 AAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQPQ 1613 +A+ AF PF GGPR CIG+ FA+ E K+A++ L RF P + + L+ Sbjct: 440 SARHSHAFLPFSGGPRNCIGKQFAMNELKVAVALTLVRFELLPDPKRVPDQKPRLVLKSS 499 Query: 1614 HGAQIRLKKI 1643 +G +RL+K+ Sbjct: 500 NGIHLRLRKL 509
>Q64464:CP3AD_MOUSE Cytochrome P450 3A13 - Mus musculus (Mouse)| Length = 503 Score = 146 bits (368), Expect = 3e-34 Identities = 111/409 (27%), Positives = 195/409 (47%), Gaps = 11/409 (2%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK+ + G P + + DP++++ +L + + F +R +L ++ E E+ Sbjct: 66 KKYGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGILKKAISISENEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCE---VDVCPEFQNLT 713 W + R +L+P F ++K M P+ + + ++ QGL E + F + Sbjct: 126 WKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMR-----QGLGEGKPTSMKDIFGAYS 180 Query: 714 GDVISRTAFGSNFQEGMKIFQLQGELSERLIQ--AFQTLFIPGYWF---FPTKNNRRMRA 878 DVI+ T+FG N E ++L++ F LF+ F P + + Sbjct: 181 MDVITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPVFDALNVSL 240 Query: 879 IDRE-IRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQEC 1055 R+ I + KE +K S ++ +++ LS +I+ + Sbjct: 241 FPRDVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTK-ESHKALSDVEIVAQS 299 Query: 1056 KLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSRLKIVTMI 1232 +F FAG ETTS L++ L +L++HP+ Q+K ++E+ P +++L +++ + M+ Sbjct: 300 VIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPNKAPATYDTLLQMEYLDMV 359 Query: 1233 FYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 E LRLYP L R +E+ G+ P G +M+P +H DP W + EF PER Sbjct: 360 VNETLRLYPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYW-PEPEEFRPER 418 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 F+ ++ P + PFG GPR CIG FAL K+AL +LQ F+ + Sbjct: 419 FSKKNQDSI-NPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQ 466
>Q64462:CP4B1_MOUSE Cytochrome P450 4B1 - Mus musculus (Mouse)| Length = 511 Score = 145 bits (365), Expect = 7e-34 Identities = 109/395 (27%), Positives = 180/395 (45%), Gaps = 16/395 (4%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 + GL EG KW +HR++L P FH++ +K + +F+ M+ +WE S D Sbjct: 122 IGKGLLVLEGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRVMLDKWEKKASENK--SFD 179 Query: 687 VCPEFQNLTGDVISRTAFG---SNFQEGMKIFQLQGE----LSERLIQAFQTLFIPGYWF 845 + + ++ D + + FG S + L L ++ I +FQ YW Sbjct: 180 IFCDVGHMALDTLMKCTFGKGDSGLSHSDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWL 239 Query: 846 FPTKNNRRMRAI-------DREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQS 1004 P R +RA D IR + +KE+ + + Sbjct: 240 TP-HGRRFLRACQIAHDHTDHVIRQRKAALQDEKEQK------KLQERRHLDFLDILLGA 292 Query: 1005 NGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG-R 1181 ++ + LS D+ E F F G +TT+ ++W L ++++P Q++ REEV G R Sbjct: 293 RDESGIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMHQQRCREEVREILGDR 352 Query: 1182 TTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAME-LGGIKYPAGVNLMLPILFI 1358 + ++ L+++ +TM E RLYPP+ + R+ K + + G PAG + L I + Sbjct: 353 DSFQWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISLHIYAL 412 Query: 1359 HHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTI 1538 H + +W D F+P RF+ + + P AF PF GPR CIGQ FA+ E K+ + Sbjct: 413 HRNSAVW-PDPEVFDPLRFSPE-NMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALC 470 Query: 1539 LQRFSFELSPSYIHAPYTVITLQPQHGAQIRLKKI 1643 L RF F PS I + L+ ++G + LK + Sbjct: 471 LLRFEFSPDPSKIPIKVPQLILRSKNGIHLYLKPL 505
>P15129:CP4B1_RAT Cytochrome P450 4B1 - Rattus norvegicus (Rat)| Length = 511 Score = 144 bits (364), Expect = 1e-33 Identities = 115/396 (29%), Positives = 182/396 (45%), Gaps = 17/396 (4%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 + GL +G KW +HR++L P FH++ +K + +F+ M+ +WE S D Sbjct: 122 IGKGLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRMMLDKWEKKASENK--SFD 179 Query: 687 VCPEFQNLTGDVISRTAFG---SNFQEGMKIFQLQGE----LSERLIQAFQTLFIPGYWF 845 + + ++ D + + FG S + L L ++ I +FQ YW Sbjct: 180 IFCDVGHMALDTLMKCTFGKGDSGLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWL 239 Query: 846 FPTKNNRRMRAI-------DREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQS 1004 P R +RA D IR + +KER K +S Sbjct: 240 TP-HGRRFLRACKIAHDHTDEVIRQRKAALQDEKER--KKIQQRRHLDFLDILLGVRDES 296 Query: 1005 NGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG-R 1181 K LS ++ E F F G +TT+ ++W L ++++PE Q+ REEV G + Sbjct: 297 GIK----LSDAELRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQ 352 Query: 1182 TTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAME-LGGIKYPAGVNLMLPILFI 1358 + ++ L+++ +TM E RLYPP+ + R+ K + + G PAG + L I + Sbjct: 353 DSFQWDDLAKMTYLTMCMKECFRLYPPVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYAL 412 Query: 1359 HHDPDIWGKDAREFNPERFADGISNAAKR-PAAFFPFGGGPRICIGQNFALQEAKMALST 1535 H + +W D F+P RF+ NAA R P AF PF GPR CIGQ FA+ E K+ + Sbjct: 413 HRNSTVW-PDPEVFDPLRFSP--ENAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTAL 469 Query: 1536 ILQRFSFELSPSYIHAPYTVITLQPQHGAQIRLKKI 1643 L RF F L PS + + L+ ++G + LK + Sbjct: 470 CLLRFEFSLDPSKMPIKVPQLILRSKNGIHLYLKPL 505
>Q02928:CP4AB_HUMAN Cytochrome P450 4A11 precursor - Homo sapiens (Human)| Length = 519 Score = 144 bits (363), Expect = 1e-33 Identities = 123/438 (28%), Positives = 199/438 (45%), Gaps = 22/438 (5%) Frame = +3 Query: 396 FGPTPRVMVPDPELVREIL--SNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILN 569 +G RV + DP+ ++ IL S+ H G R + + GL G+ W +HRR+L Sbjct: 91 WGGKVRVQLYDPDYMKVILGRSDPKSH-GSYRF--LAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 570 PAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQN---LTGDVISRTAF 740 PAFH++ +K + + + M+ +WE + EV FQ+ +T D I + AF Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEV-----FQHVSLMTLDTIMKCAF 202 Query: 741 GS--------NFQEGMK-IFQLQGELSERLIQAFQ------TLFIPGYWFFPTKNNRRMR 875 N Q ++ I L + R+ AF +L G W Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQH 262 Query: 876 AIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQEC 1055 ++ + + + K+ K + M+ NG LS +D+ E Sbjct: 263 T--DQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKME--NGSI---LSDKDLRAEV 315 Query: 1056 KLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMI 1232 F F G +TT+ ++W L L+ HP+ QE+ REE+ G + + L ++ TM Sbjct: 316 DTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMC 375 Query: 1233 FYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPE 1409 E LRLYPP+ + R + G P G+ ++L I +HH+P +W + F+P Sbjct: 376 IKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPF 434 Query: 1410 RFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPY 1589 RFA G +A+ AF PF GG R CIG+ FA+ E K+A + L RF P+ I P Sbjct: 435 RFAPG---SAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPI 491 Query: 1590 TVITLQPQHGAQIRLKKI 1643 + L+ ++G +RL+++ Sbjct: 492 ARLVLKSKNGIHLRLRRL 509
>Q64148:CP3AA_MESAU Cytochrome P450 3A10 - Mesocricetus auratus (Golden hamster)| Length = 503 Score = 144 bits (363), Expect = 1e-33 Identities = 113/411 (27%), Positives = 190/411 (46%), Gaps = 13/411 (3%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK+ + G P + + DPE+++ +L + + +F +RS + + + E+ Sbjct: 66 KKYGKIWGFYDGRVPVLAIADPEIIKTVLVKECYSNFTNRRSFGPVGFMKKSITISKDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMIT---RWENSMSAQGLCEVDVCPEFQNLT 713 W + R +L+PAF K+K M P+ + ++ R E + E+ + Sbjct: 126 WKRLRTLLSPAFTSGKLKEMFPIIGQYGDTLVKNLRREEEKGKPVNMKEI-----LGAYS 180 Query: 714 GDVISRTAFGSNFQEGMKIFQLQGELSERLIQA-FQTLFIPGYWFFPTKNN----RRMRA 878 DVI+ T+FG N + + ++++ F FI FP R Sbjct: 181 MDVITGTSFGVNVDSLNNPEDPFVQKARKILKFNFFDPFILSIILFPFLTTIYDLLRFSI 240 Query: 879 IDREIRMILRGIIG--KKERAIKNXXXXXXXXXXXXXXSNMQQSNGK-ANLGLSIEDIIQ 1049 R+ + I KK R N N Q S GK + LS ++ Sbjct: 241 FPRQSTNFFKKFITTMKKNRLHSNQKTRMDFFQLMM---NTQNSKGKESQKALSDLEMAA 297 Query: 1050 ECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSRLKIVT 1226 + +F FAG E+TS + L L+ HP+ Q+K +E+ P ++ L ++ + Sbjct: 298 QAIIFIFAGYESTSTSICLVLYELATHPDVQKKLHDEIDSALPNKAPVTYDVLMGMEYLD 357 Query: 1227 MIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNP 1406 M+ E LRLYP L R + KA+E+ G+ P G+ +M+P +H DP+ W + EF P Sbjct: 358 MVINEGLRLYPIANRLERISKKAVEINGLFIPKGITVMVPTYPLHRDPEYW-PEPEEFRP 416 Query: 1407 ERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 ERF+ + + P + PFG GPR CIG FAL K+A+ ++LQ F+ + Sbjct: 417 ERFSKE-NKGSIDPYVYMPFGNGPRNCIGMRFALLSMKLAVVSVLQNFTLQ 466
>P05184:CP3A3_HUMAN Cytochrome P450 3A3 - Homo sapiens (Human)| Length = 504 Score = 144 bits (363), Expect = 1e-33 Identities = 105/409 (25%), Positives = 194/409 (47%), Gaps = 11/409 (2%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GKV + G P + + DP++++ +L + + F + + + ++ E E+ Sbjct: 66 KKYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+P F K+K M+P+ + + ++ V + F + DV Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGK--PVTLKDVFGAYSMDV 183 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWF--------FPTKNNRRMRA 878 I+ ++FG N + Q L E + + F+ ++ P + Sbjct: 184 ITSSSFGVNVDS---LNNPQDPLVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICV 240 Query: 879 IDREIRMILRGIIGK-KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQEC 1055 RE+ LR + + KE +++ S+ +++ LS +++ + Sbjct: 241 FPREVTNFLRKAVKRMKESRLEDTQKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQS 300 Query: 1056 KLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMI 1232 +F FAG ETTS +L++ + L+ HP+ Q+K +EE+ + P ++++ +++ + M+ Sbjct: 301 IIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 360 Query: 1233 FYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 E LRL+P L R K +E+ G+ P G +M+P +H DP W + +F PER Sbjct: 361 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW-TEPEKFLPER 419 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 F+ + P + PFG GPR CIG FAL K+AL +LQ FSF+ Sbjct: 420 FSKKNKDNID-PYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 467
>Q2KIG5:THAS_BOVIN Thromboxane-A synthase - Bos taurus (Bovine)| Length = 533 Score = 144 bits (362), Expect = 2e-33 Identities = 116/467 (24%), Positives = 207/467 (44%), Gaps = 44/467 (9%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIG-RLLANGLANHEGEK 542 K++G +S + G +++ +P+++ ++L KF +F + +T + + +A+ + ++ Sbjct: 72 KQYGPLSGYYLGRLMFIVISEPDMIEQVLVEKFSNFTNRMATGLEPKPVADSVLFLRDKR 131 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L AF EK+ M P+ S C+ ++ E AQ D+ + T DV Sbjct: 132 WEEVRSVLTVAFSPEKLSEMTPLISRACDVLLAHLERH--AQSGEAFDIQRTYCCYTTDV 189 Query: 723 ISRTAFGSN----------FQEGMKIFQLQGELSERLIQ--AFQTLFIPGYWFFPTKNNR 866 ++ AFG+ F E + F L+ +F ++ +P P KN Sbjct: 190 VASVAFGTEVNSQEAPEHPFVEHCRRFFASSIPKPLLVLLLSFPSIMVPLARILPNKNRD 249 Query: 867 RMRAIDREIRMILRGIIGKKER------------------------AIKNXXXXXXXXXX 974 + ++R +I +++ ++ Sbjct: 250 ELNGF---FNKLIRNVIALRDQQAAEERRRDFLQMVQDVRHSAATVGVEKFDIVRQVFSA 306 Query: 975 XXXXSNMQQSNGKANLG--LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEK 1148 +N + + L LS+++++ + +F AG E + L++ +L+ +PE QEK Sbjct: 307 TKCPANPPRRHSPRPLSKPLSVDEVVGQAFIFLIAGYEIVTNTLSFATYLLATNPECQEK 366 Query: 1149 AREEVLHYFGR-TTPDFESLSR-LKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYP 1322 EEV + P++ SL L + M+ E LR+YPP TR + E+ G + P Sbjct: 367 LLEEVDCFSKEHLAPEYCSLQEGLPYLDMVIKETLRMYPPAFRFTRVAAQDCEVLGQRIP 426 Query: 1323 AGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNF 1502 AG L + +H+DP+ W + FNPERF + +RP + PFG GPR C+G Sbjct: 427 AGAVLETAVGALHYDPEHW-PNPENFNPERFT-AEAQQRRRPYTYLPFGAGPRSCLGVRL 484 Query: 1503 ALQEAKMALSTILQRFSFELSPSYIHAPYTV---ITLQPQHGAQIRL 1634 L E K+ L IL++F FE P P + L P++G IR+ Sbjct: 485 GLLELKLTLLHILRKFRFEACPE-TQVPLQLESKSALGPKNGVYIRI 530
>Q9VXY0:CP4S3_DROME Probable cytochrome P450 4s3 - Drosophila melanogaster (Fruit fly)| Length = 495 Score = 144 bits (362), Expect = 2e-33 Identities = 133/481 (27%), Positives = 201/481 (41%), Gaps = 27/481 (5%) Frame = +3 Query: 276 RFNAEARSQPMPPGSHHIAPRVLPMFTNAIKE----HGKVSFTWFGPTPRVMVPDPELVR 443 R A++ P P IA N +KE HG V WFG VM DPE ++ Sbjct: 27 RLQRFAKTLPGPTIGELIANVKKGEILNWLKELREKHGPVFRIWFGKDLMVMFTDPEDIK 86 Query: 444 EILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSAC 623 ++L N + + L GL + GE W + R++L P FH + Sbjct: 87 QLLGNNQLLTKSRNYELLEPWLGKGLLTNGGESWHRRRKLLTPGFHFRILSEFKEPMEEN 146 Query: 624 CEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERL 803 C ++ R + + D+ P D I TA G K QLQ + Sbjct: 147 CRILVRRLRTKANGESF---DIYPYITLFALDAICETAMGIK-----KHAQLQSD--SEY 196 Query: 804 IQAFQTLFIP------GYW------FFPTKNNRRMRAI--------DREIRMILRGIIGK 923 +QA Q++ +W F TK + A +R IR+ +I + Sbjct: 197 VQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLIQE 256 Query: 924 KERAIKNXXXXXXXXXXXXXXSNM---QQSNGKANLGLSIEDIIQECKLFYFAGMETTSV 1094 + +M Q G A L S DI +E F F G +TTS Sbjct: 257 RNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAEL--SDTDIREEVDTFMFEGHDTTSS 314 Query: 1095 LLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFL 1274 + + L +LS +P+ Q++A EE GR + ES+ L+ V E LR+YP + F Sbjct: 315 AIAFALSLLSKNPDVQQRAFEEASELEGR---EKESMPYLEAVIK---ETLRIYPSVPFF 368 Query: 1275 TRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAA 1454 +R+ + +E+G + P G ++ I +H DP + D F+P+RF ++ P A Sbjct: 369 SRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNF-PDPERFDPDRFL--VNEKQMHPFA 425 Query: 1455 FFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQPQHGAQIRL 1634 F F GPR CIGQ FA+ E K +L+ +L+ S+ P H P + L + G IRL Sbjct: 426 FAAFSAGPRNCIGQKFAMLELKTSLAMLLR--SYRFLPDKDHQPKPLAELVTKSGNGIRL 483 Query: 1635 K 1637 + Sbjct: 484 R 484
>P08516:CP4AA_RAT Cytochrome P450 4A10 - Rattus norvegicus (Rat)| Length = 509 Score = 143 bits (360), Expect = 3e-33 Identities = 112/437 (25%), Positives = 197/437 (45%), Gaps = 20/437 (4%) Frame = +3 Query: 393 WF-GPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN----GLANHEGEKWAKHR 557 WF G ++V DP+ ++ IL ++ + RLLA GL G+ W +HR Sbjct: 88 WFWGSKAYLIVYDPDYMKVILGRS-----DPKANGVYRLLAPWIGYGLLLLNGQPWFQHR 142 Query: 558 RILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTA 737 R+L PAFH++ +K + + M+ +WE +++ +T D + + A Sbjct: 143 RMLTPAFHYDILKPYVKNMADSIRLMLDKWEQLAGQDS--SIEIFQHISLMTLDTVMKCA 200 Query: 738 FGSNFQEGM-----KIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMI 902 F N + Q G L++ + +F + +N + +R ++ Sbjct: 201 FSHNGSVQVDGNYKSYIQAIGNLNDLFHSRVRNIFHQNDTIYNFSSNGHL--FNRACQLA 258 Query: 903 ---LRGIIGKKERAIKNXXXXXXXXXXXXXXSN-----MQQSNGKANLGLSIEDIIQECK 1058 G+I ++ ++N + NG + LS +D+ E Sbjct: 259 HDHTDGVIKLRKDQLQNAGELEKVKKKRRLDFLDILLLARMENGDS---LSDKDLRAEVD 315 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIF 1235 F F G +TT+ ++W L+ HPE Q++ REEV G ++ ++ L ++ TM Sbjct: 316 TFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSVLGDGSSITWDHLDQIPYTTMCI 375 Query: 1236 YEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 E LRLYPP+ + R ++ G P G+ + L I +HH+P +W + F+P R Sbjct: 376 KEALRLYPPVPGIVRELSTSVTFPDGRSLPKGIQVTLSIYGLHHNPKVW-PNPEVFDPSR 434 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYT 1592 FA ++ + +F PF GG R CIG+ FA+ E K+ ++ L RF P+ + P Sbjct: 435 FAP---DSPRHSHSFLPFSGGARNCIGKQFAMSEMKVIVALTLLRFELLPDPTKVPIPLP 491 Query: 1593 VITLQPQHGAQIRLKKI 1643 + L+ ++G + LKK+ Sbjct: 492 RLVLKSKNGIYLYLKKL 508
>P14581:CP4A7_RABIT Cytochrome P450 4A7 precursor - Oryctolagus cuniculus (Rabbit)| Length = 511 Score = 143 bits (360), Expect = 3e-33 Identities = 105/390 (26%), Positives = 178/390 (45%), Gaps = 14/390 (3%) Frame = +3 Query: 516 GLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCP 695 GL EG+ W +HRR+L PAFH++ +K + + + M+ + E A+ +++ Sbjct: 130 GLLLLEGQTWFQHRRMLTPAFHYDILKPYVGLMVDSVQVMLDKLEKL--ARKDAPLEIYE 187 Query: 696 EFQNLTGDVISRTAFGSN------FQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTK 857 +T + I + AF + Q ELS+ +Q + +F + + Sbjct: 188 HVSLMTLETIMKCAFSHQGSVQLESRTSKSYIQAVRELSDLALQRVRNVFHQSDFLYRLS 247 Query: 858 NNRRMR------AIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKAN 1019 R+ A + R+I + ++ + NG + Sbjct: 248 PEGRLSHRACQLAHEHTDRVIQQRKAQLQQEGELEKVRRKRRLDFLDVLLFAKMENGSS- 306 Query: 1020 LGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDF 1196 LS +D+ E F F G +TT+ ++W L+ HPE Q + REE+ G + + Sbjct: 307 --LSDQDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQHRCREEIQGLLGDGASITW 364 Query: 1197 ESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPD 1373 E L ++ TM E LRLYPP+ + + + G P G+ + L I +HH+P Sbjct: 365 EHLDKMPYTTMCIKEALRLYPPVPGVGSKLSSPVTFPDGRSLPKGIIITLSIYGLHHNPK 424 Query: 1374 IWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFS 1553 +W + F+P RFA G +A+ AF PF GG R CIG+ FA+ E K+A++ L RF Sbjct: 425 VW-PNPEVFDPSRFAPG---SARHSHAFLPFSGGSRNCIGKQFAMNELKVAVALTLVRFE 480 Query: 1554 FELSPSYIHAPYTVITLQPQHGAQIRLKKI 1643 P+ + P T + L+ ++G +RL+K+ Sbjct: 481 LLPDPTRVPIPITRLVLKSKNGIHLRLRKL 510
>Q64481:CP3AG_MOUSE Cytochrome P450 3A16 - Mus musculus (Mouse)| Length = 504 Score = 142 bits (359), Expect = 4e-33 Identities = 109/411 (26%), Positives = 188/411 (45%), Gaps = 13/411 (3%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 +++GK + G P ++ DPE ++ +L + F F ++ +++ ++ + E+ Sbjct: 66 EKYGKTWGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGIMSKSISLAKDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W ++R +L+P F +K M PV +++ ++ + +G V V + DV Sbjct: 126 WKRYRALLSPTFTSGNLKEMFPVIEQY-GDILVKYLRQEAEKGK-PVAVKDVLGAYSMDV 183 Query: 723 ISRTAFGSNF-----------QEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRR 869 I T FG N + K+ + L A P Y N Sbjct: 184 IISTTFGVNIDSLNNPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTPIYEML----NIC 239 Query: 870 MRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQ 1049 M D I + + E + + + + + ++ LS +I Sbjct: 240 MFPKD-SIEFFKKFVDRMTENRLDSKQKHRVDFIYLMMEAYNKSKDKDSHKALSEIEITA 298 Query: 1050 ECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVT 1226 + +F FAG ETTS +L++T+ L+ HP+ Q+K +EE+ + P ++++ ++ + Sbjct: 299 QSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPPTYDTVMAMEYLD 358 Query: 1227 MIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNP 1406 M+ E LRLYP L R K +E+ GI P G +++P +HHDP W + EF P Sbjct: 359 MVLNETLRLYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHW-PEPEEFQP 417 Query: 1407 ERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 ERF+ + + P + PFG GPR CIG FAL K+AL +LQ FSF+ Sbjct: 418 ERFSKE-NKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQ 467
>O18993:CP3AL_CALJA Cytochrome P450 3A21 - Callithrix jacchus (Common marmoset)| Length = 503 Score = 142 bits (358), Expect = 5e-33 Identities = 108/406 (26%), Positives = 196/406 (48%), Gaps = 8/406 (1%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK+ + G P + + DP +++ +L + + F +R + + ++ + ++ Sbjct: 66 KKYGKMWGIYDGRQPVLAITDPNIIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAQDDE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+P F K+K M+P+ + E ++ A+ +++ F + DV Sbjct: 126 WKRIRSLLSPTFTSGKLKEMVPIIAQYGEVLVRNLRR--EAEKGKPINMKDIFGAYSMDV 183 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSERLIQ-AFQTLFIPGYWFF----PTKNNRRMRAIDR 887 I+ T+FG N E +++L++ F F F P + R Sbjct: 184 ITGTSFGVNIDSLNNPQDPFVESTKKLLRFDFLDPFFLSITIFPFLTPILEALNISMFPR 243 Query: 888 EIRMILRGIIGK-KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLF 1064 + LR I + KE +K+ S + +++ LS +++ + +F Sbjct: 244 DSTSFLRKSIKRIKESRLKDTHKHRVDFLQLMIDSQNSKET-ESDKALSDLELVAQSIIF 302 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSRLKIVTMIFYE 1241 FAG ETTS L++ + L+ HP+ Q+K +EE+ P ++++ +++ + M+ E Sbjct: 303 IFAGYETTSSTLSFIMYELATHPDVQQKLQEEIDAVLPNKAPATYDTVLQMEYLDMVVNE 362 Query: 1242 VLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFAD 1421 LRL+P L R K +E+ G+ P GV +M+P +H+DP W + +F PERF+ Sbjct: 363 TLRLFPLAMRLERVCKKDVEINGVFIPKGVVVMIPSYALHYDPKYW-TEPEKFLPERFSK 421 Query: 1422 GISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 + P + PFG GPR CIG FAL K+AL +LQ FSF+ Sbjct: 422 NNKDNID-PYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>P24464:CP4AC_RAT Cytochrome P450 4A12 - Rattus norvegicus (Rat)| Length = 508 Score = 142 bits (357), Expect = 6e-33 Identities = 117/444 (26%), Positives = 197/444 (44%), Gaps = 28/444 (6%) Frame = +3 Query: 396 FGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN----GLANHEGEKWAKHRRI 563 +G R+ V DP+ ++ IL +S R LA GL G+ W +HRR+ Sbjct: 89 WGSNVRIQVYDPDYMKLILGRS-----DPKSHHSYRFLAPWIGYGLLLLNGQTWFQHRRM 143 Query: 564 LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTG---DVISRT 734 L PAFH++ +K + + + M+ +WE + E+ FQ++T D I + Sbjct: 144 LTPAFHYDTLKPYVGIMADSVRIMLDKWEQIVGQDSTLEI-----FQHITLMTLDTIMKC 198 Query: 735 AFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAI-------DREI 893 AF QEG + + + ++ L FF +N I R+ Sbjct: 199 AFS---QEGSVQLDRKYKSYIKAVEDLNNLS-----FFRIRNIFHQNDIIYSLSSNGRKA 250 Query: 894 RMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQ------------SNGKANLGLSIE 1037 R + ++ IK+ ++ NG + LS + Sbjct: 251 RSAWQLAHEHTDQVIKSRKAQLQDEEELQKVKQKRRLDFLDILLFARIENGSS---LSDK 307 Query: 1038 DIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRL 1214 D+ E F F G +TT+ ++W L+ +PE Q+ R+E+ G + ++ L ++ Sbjct: 308 DLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQGCRKEIQSLLGDGASITWDDLDKM 367 Query: 1215 KIVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDA 1391 TM E LR+YPP+T ++R + G P G+ +ML +HH+P +W + Sbjct: 368 PYTTMCIKEALRIYPPVTAVSRMLSTPVTFPDGRSLPKGITVMLSFYGLHHNPTVW-PNP 426 Query: 1392 REFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPS 1571 F+P RFA +++ +F PF GG R CIG+ FA+ E K+A++ L RF P+ Sbjct: 427 EVFDPYRFAP---ESSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPT 483 Query: 1572 YIHAPYTVITLQPQHGAQIRLKKI 1643 I P + L+ ++G +RLKK+ Sbjct: 484 RIPIPIPRLVLKSKNGIYLRLKKL 507
>P13584:CP4B1_HUMAN Cytochrome P450 4B1 - Homo sapiens (Human)| Length = 511 Score = 141 bits (355), Expect = 1e-32 Identities = 114/401 (28%), Positives = 187/401 (46%), Gaps = 22/401 (5%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 + GL EG KW +HR++L P FH++ +K + VF+ M+ +WE A+ D Sbjct: 122 IGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEK--AREGKSFD 179 Query: 687 VCPEFQNLTGDVISRTAFGS--------NFQEGMKIFQLQGELSERLIQ-AFQTLFIPGY 839 + + ++ + + + FG + + + L + +RL+ + FI Y Sbjct: 180 IFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFI--Y 237 Query: 840 WFFPTKNNRRMRAI-------DREIRMILRGIIGKKERA-IKNXXXXXXXXXXXXXXSNM 995 W P R +RA D+ IR + +K R I+N + Sbjct: 238 WLTP-HGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDI-------L 289 Query: 996 QQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF 1175 + + ++ LS D+ E F F G +TT+ ++W L ++++PE Q + REEV Sbjct: 290 LGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREIL 349 Query: 1176 GRTTPDF---ESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAME-LGGIKYPAGVNLML 1343 G DF + L ++ +TM E RLYPP+ + R+ K + + G PAG + + Sbjct: 350 G--DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISM 407 Query: 1344 PILFIHHDPDIWGKDAREFNPERFADGISNAAKR-PAAFFPFGGGPRICIGQNFALQEAK 1520 I +H + +W D F+ RF+ NA+KR P AF PF GPR CIGQ FA+ E K Sbjct: 408 HIYALHRNSAVW-PDPEVFDSLRFST--ENASKRHPFAFMPFSAGPRNCIGQQFAMSEMK 464 Query: 1521 MALSTILQRFSFELSPSYIHAPYTVITLQPQHGAQIRLKKI 1643 + + L RF F L PS + + L+ ++G + LK + Sbjct: 465 VVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPL 505
>P24462:CP3A7_HUMAN Cytochrome P450 3A7 - Homo sapiens (Human)| Length = 503 Score = 141 bits (355), Expect = 1e-32 Identities = 111/412 (26%), Positives = 200/412 (48%), Gaps = 14/412 (3%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++ KV + P + + DP++++ +L + + F +R + N ++ E E+ Sbjct: 66 KKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+P F K+K M+P+ + + ++ A+ V + F + DV Sbjct: 126 WKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRE--AETGKPVTLKHVFGAYSMDV 183 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTL--FIPGYWFFPTKNNRRMRAID---- 884 I+ T+FG + E +++L++ F L F+ FP + A++ Sbjct: 184 ITSTSFGVSIDSLNNPQDPFVENTKKLLR-FNPLDPFVLSIKVFPFLTPI-LEALNITVF 241 Query: 885 --REIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECK 1058 + I + + + KE +K S + + + LS +++ + Sbjct: 242 PRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQ-NSKDSETHKALSDLELMAQSI 300 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIF 1235 +F FAG ETTS +L++ + L+ HP+ Q+K ++E+ + P ++++ +L+ + M+ Sbjct: 301 IFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVV 360 Query: 1236 YEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 E LRL+P L R K +E+ G+ P GV +M+P +HHDP W ++ +F PERF Sbjct: 361 NETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYW-REPEKFLPERF 419 Query: 1416 A----DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 + D I P + PFG GPR CIG FAL K+AL +LQ FSF+ Sbjct: 420 SKKNKDNID-----PYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFK 466
>P29981:CP4C1_BLADI Cytochrome P450 4C1 - Blaberus discoidalis (Tropical cockroach)| Length = 511 Score = 140 bits (353), Expect = 2e-32 Identities = 124/429 (28%), Positives = 189/429 (44%), Gaps = 21/429 (4%) Frame = +3 Query: 327 IAPR--VLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIG 500 I PR + +F K +G + W GP +V + PE V IL + H K Sbjct: 53 IVPRNKLFQVFDRRAKLYGPLYRIWAGPIAQVGLTRPEHVELILRDT-KHIDKSLVYSFI 111 Query: 501 R-LLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLC 677 R L GL G KW HR+++ P FH + + + VF E ++ + ++ + + Sbjct: 112 RPWLGEGLLTGTGAKWHSHRKMITPTFHFKILDIFVDVFVEKSEILVKKLQSKVGGK--- 168 Query: 678 EVDVCPEFQNLTGDVISRTAFG--SNFQEGMKIFQLQG--ELSERLIQ-AFQTLFIPGYW 842 + D+ P + D+I TA G N QE + ++ E+SE +Q + + P Sbjct: 169 DFDIYPFITHCALDIICETAMGIQMNAQEESESEYVKAVYEISELTMQRSVRPWLHPKVI 228 Query: 843 FFPTKNNRRMRAIDREI----------RMILRGIIGKKERAIKNXXXXXXXXXXXXXXSN 992 F T +R R + R LR + G K I N + Sbjct: 229 FDLTTMGKRYAECLRILHGFTNKVIQERKSLRQMTGMKP-TISNEEDELLGKKKRLAFLD 287 Query: 993 MQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHY 1172 + + +S DI +E F F G +TTS + W L +L HPE Q+K EE+ H Sbjct: 288 LLLEASENGTKMSDTDIREEVDTFMFEGHDTTSAGICWALFLLGSHPEIQDKVYEELDHI 347 Query: 1173 FGRT--TPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLP 1346 F + + L+ +K + + E LRL+P + F+ R + ++G PAG + L Sbjct: 348 FQGSDRSTTMRDLADMKYLERVIKESLRLFPSVPFIGRVLKEDTKIGDYLVPAGCMMNLQ 407 Query: 1347 ILFIHHDPDIWGKDAREFNPERFADGISNAAKR-PAAFFPFGGGPRICIGQNFALQEAKM 1523 I +H + D + + FNP+ F AKR P A+ PF GPR CIGQ FA E K Sbjct: 408 IYHVHRNQDQY-PNPEAFNPDNFLP--ERVAKRHPYAYVPFSAGPRNCIGQKFATLEEKT 464 Query: 1524 ALSTILQRF 1550 LS+IL+ F Sbjct: 465 VLSSILRNF 473
>Q9V770:C6A17_DROME Probable cytochrome P450 6a17 - Drosophila melanogaster (Fruit fly)| Length = 501 Score = 140 bits (353), Expect = 2e-32 Identities = 114/432 (26%), Positives = 194/432 (44%), Gaps = 19/432 (4%) Frame = +3 Query: 405 TPRVMVPDPELVREILSNKFGHFGKQRS--TRIGRLLANGLANHEGEKWAKHRRILNPAF 578 T +V D EL++ +L F HF + I L+ L + EG+KW R L P F Sbjct: 77 TRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTF 136 Query: 579 HHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQE 758 K+K M P+ EEM + + +A ++V T DVI AFG N Sbjct: 137 TSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVLEVVDLVARYTADVIGNCAFGLNCNS 196 Query: 759 GMKIFQLQGE--------LSERLIQAFQTLFIPGYWFFPTKNNR-RMRAIDREIRMILRG 911 ++ + E ++E +F+ G FP + R R++ +E Sbjct: 197 ---LYDPKAEFVSIGKRAITEHRYGNMLDIFLFG---FPKLSRRLRLKLNIQEAEDFYTK 250 Query: 912 IIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTS 1091 I+ + + +G + GL+ +++ + +F+ AG ET+S Sbjct: 251 IVRETIDYRLRTKEKRNDFMDSLIEMYKNEQSGNSEDGLTFNELLAQAFIFFVAGFETSS 310 Query: 1092 VLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDF--ESLSRLKIVTMIFYEVLRLYPPI 1265 + + L L+ + + Q+K REE+ + FG+ +F E + +K + + E LR YP + Sbjct: 311 TTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVL 370 Query: 1266 TFLTRRTYKAMELGGIKY--PAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAA 1439 LTR T KY G +++P L IH+DPDI+ + F PERF D AA Sbjct: 371 AHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIY-PEPEIFKPERFTDE-EIAA 428 Query: 1440 KRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTV----ITLQ 1607 + + PFG GPR CIG F + + + L+ +++ + F +SP P + I + Sbjct: 429 RPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPE-TQIPMKIVVKNILIS 487 Query: 1608 PQHGAQIRLKKI 1643 ++G ++++K+ Sbjct: 488 AENGIHLKVEKL 499
>P47787:THAS_PIG Thromboxane-A synthase - Sus scrofa (Pig)| Length = 534 Score = 140 bits (352), Expect = 2e-32 Identities = 109/468 (23%), Positives = 210/468 (44%), Gaps = 45/468 (9%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRI-GRLLANGLANHEGEK 542 K++G +S + G V++ DP++++++L+ KF +F + +T + + +A+ + ++ Sbjct: 72 KQYGPLSGYYLGRRMIVVISDPDMIKQVLAEKFSNFTNRMATGLESKPVADSILFLRDKR 131 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L AF +K+ ++ P+ S C+ ++ E + ++ C + T DV Sbjct: 132 WEEVRSVLTSAFSPKKLNKLTPLISQACDLLLAHLERYAESGDAFDIQRC--YCCYTTDV 189 Query: 723 ISRTAFGSNFQEG-----------MKIFQLQ-GELSERLIQAFQTLFIPGYWFFPTKNNR 866 ++ AFG+ + F L LI +F ++ +P P N+ Sbjct: 190 VASVAFGTQVNSSEEPEHPFVKHCRRFFAFSVPRLILVLILSFPSIMVPLARILP---NK 246 Query: 867 RMRAIDREIRMILRGIIGKKERA---------------IKNXXXXXXXXXXXXXXSNMQQ 1001 + ++ ++R +I +++ +++ Sbjct: 247 KRDEVNGFFNKLIRNVIALRDQQAAEERRQDFLQMVLDLRHSAPSVGVENFDIVRQAFSS 306 Query: 1002 SNG------------KANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQE 1145 + G + L++++++ + LF AG E + L++ +L+ +P+ QE Sbjct: 307 AKGCPADPSQPHLPRPLSKPLTVDEVVGQAFLFLIAGYEIITNTLSFVTYLLATNPDCQE 366 Query: 1146 KAREEVLHYFGR-TTPDFESLSR-LKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKY 1319 K EV + + +P+ SL + L + M+ E LR+YPP TR + E+ G + Sbjct: 367 KLLREVDDFSKKHPSPEHCSLQQGLPYLDMVLSETLRMYPPAFRFTREAARDCEVLGQRI 426 Query: 1320 PAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQN 1499 PAG L + + +HHDP W F+PERF + ++P + PFG GPR C+G Sbjct: 427 PAGTVLEVAVGALHHDPKHW-PHPETFDPERFT-AEAQRLQQPFTYLPFGAGPRSCLGVQ 484 Query: 1500 FALQEAKMALSTILQRFSFELSPSYIHAPYTV---ITLQPQHGAQIRL 1634 L E K+ L IL++F FE P P + L P++G IR+ Sbjct: 485 LGLLEIKLTLLHILRKFRFEACPE-TQVPLQLESKSALSPKNGVYIRI 531
>Q64417:CP3AE_CAVPO Cytochrome P450 3A14 - Cavia porcellus (Guinea pig)| Length = 503 Score = 140 bits (352), Expect = 2e-32 Identities = 111/429 (25%), Positives = 192/429 (44%), Gaps = 21/429 (4%) Frame = +3 Query: 333 PRVLPMFTNAI--------------KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FG 467 P+ LP+F N + K++G + + GP P + + +P++++ +L + + Sbjct: 41 PKPLPLFGNVLSYRKGMWSFDIECRKKYGNMWGLYDGPQPVLAITEPDMIKAVLVKECYS 100 Query: 468 HFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRW 647 F +RS + ++ E E+W + R L+P F K+K M P+ + ++ Sbjct: 101 VFTNRRSLVPVGFMKKAVSLSEDEEWKRIRTQLSPNFTSGKLKEMFPIIKQYGDVLVKNL 160 Query: 648 ENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQA-FQTL 824 A+ V + F + D+I TAFG N + +L + F + Sbjct: 161 RQE--AEKGKPVQLKEIFGAYSMDIIVATAFGVNVDSLNNPHDPFVSKARKLFRFDFLSP 218 Query: 825 FIPGYWFFPTKNNR-RMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQ 1001 F+ FP M +I R L+ ++ +N + Sbjct: 219 FLLSIVMFPFLTQLYEMLSISIFPRDSLKFFTKFVKKTKENHLESNKKQRVDFLQMMLNS 278 Query: 1002 SNGK---ANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHY 1172 N K ++ LS +I+ + +F FAG ETTS L++ + L+ HP+ Q+K ++E+ Sbjct: 279 QNFKDTESHKALSDVEILAQSIIFIFAGYETTSSTLSFIMYSLATHPDVQKKLQQEIDKT 338 Query: 1173 F-GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPI 1349 + P ++ + ++ + M+ E LRLYP + R + K E+ G+ +P G +M+P Sbjct: 339 LPNKAFPTYDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKDFEINGMSFPKGTGVMIPS 398 Query: 1350 LFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMAL 1529 +H D W + EF PERF+ + P + PFG GPR CIG AL K+AL Sbjct: 399 FALHRDSKYW-PEPDEFRPERFSKK-NKENIDPYIYMPFGNGPRNCIGMRMALMNLKLAL 456 Query: 1530 STILQRFSF 1556 +LQ FSF Sbjct: 457 IRLLQNFSF 465
>Q9VGB4:CP132_DROME Probable cytochrome P450 313a2 - Drosophila melanogaster (Fruit fly)| Length = 493 Score = 140 bits (352), Expect = 2e-32 Identities = 107/422 (25%), Positives = 182/422 (43%), Gaps = 15/422 (3%) Frame = +3 Query: 354 TNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFG-HFGKQRSTRIGRLLANGLANH 530 T + +HG W G TP V+ DP++ ++L++ F + Q + + + GL Sbjct: 59 TTYMDKHGSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTL 118 Query: 531 EGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNL 710 +G KW R+ +NPAF H + LP+F+A + +++ ++ S QG E DV + Sbjct: 119 QGSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFD-SFVGQG--EKDVLSDLIRW 175 Query: 711 TGDVISRTAFGS------NFQEGMKIFQLQGELSERLIQAF----QTLFIPGYWFFPTKN 860 + + ++T G+ NF+ + Q L +I F Q + + Sbjct: 176 SFAIATQTTLGTDVTKDDNFENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFGLEWLR 235 Query: 861 NRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIED 1040 R AI++ I IL + N + +S+ + Sbjct: 236 RRDASAINKMINNILDKKLNSNPENYCESELKTVIHRAIELFRNDE---------MSLME 286 Query: 1041 IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRT---TPDFESLSR 1211 + EC A ET++ + + L++L+M PE QE E+ +F L + Sbjct: 287 LGAECSSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQ 346 Query: 1212 LKIVTMIFYEVLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKD 1388 L + + E LRL P + F +R T + + L G+ P G+ + + I + D WG + Sbjct: 347 LVYLDRVLNETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSE 406 Query: 1389 AREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSP 1568 A +FNPE F + + P AF PF G R CIG + L +K+AL IL+ + + S Sbjct: 407 AAQFNPENFLPEKIH-DRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSF 465 Query: 1569 SY 1574 Y Sbjct: 466 PY 467
>Q27516:C13A8_CAEEL Putative cytochrome P450 CYP13A8 - Caenorhabditis elegans| Length = 509 Score = 140 bits (352), Expect = 2e-32 Identities = 115/431 (26%), Positives = 201/431 (46%), Gaps = 33/431 (7%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF-GKQRSTRIGRLLANG---LANHE 533 KE+GK+ G +++ DP+LV+EIL ++ +F G++ + G + + + Sbjct: 57 KEYGKIYGFTEGMQKVMVISDPDLVQEILVKQYDNFYGRKHNPVQGDPDKDKDIHIVGAQ 116 Query: 534 GEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLT 713 G +W + R I PAF + IK++L +E++ + S G V++ +Q T Sbjct: 117 GFRWKRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREE-SENGKA-VNMHLFYQEYT 174 Query: 714 GDVISRTAFGSNFQEGMK---IFQLQGELSERLIQAFQTLFIPGY--------WFFPTKN 860 DVISR A G + K + ++G Q + +F G+ W F Sbjct: 175 FDVISRVAMGQPDSQMFKNPLLKDVKGFFEHNRWQIW--MFSGGFPFAVSFLKWLFIKVG 232 Query: 861 N---RRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQ----------- 998 + + + + I ++E K+ N + Sbjct: 233 KFGAGPFIVVQKSVTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEVEHFGESND 292 Query: 999 ---QSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLH 1169 +S+ N L+ ++II +C +F AG +TT++ L++ L+++P+ Q K ++EV Sbjct: 293 EFHKSSSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVDK 352 Query: 1170 YFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFL-TRRTYKAMELGGIKYPAGVNLMLP 1346 F+ LS+LK + + E LRL+P +F +RR + +G AGV++M+ Sbjct: 353 ECPNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVIGEQIVEAGVDVMID 412 Query: 1347 ILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMA 1526 +HHD ++WG D EF PER+ ++ A+ FG GPR+C+G FAL E K Sbjct: 413 TWTLHHDKNVWGNDVEEFKPERWDSPLTPQQ----AYLSFGAGPRVCLGMRFALLEQKGL 468 Query: 1527 LSTILQRFSFE 1559 LS IL++++FE Sbjct: 469 LSHILKKYTFE 479
>Q27589:CP4D2_DROME Cytochrome P450 4d2 - Drosophila melanogaster (Fruit fly)| Length = 501 Score = 139 bits (351), Expect = 3e-32 Identities = 116/445 (26%), Positives = 199/445 (44%), Gaps = 21/445 (4%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRL-LANGLANHEGEK 542 +++G++ W V DP + +LS++ H K ++ L +GL G K Sbjct: 63 RKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQ-QHITKNNLYKLLNCWLGDGLLMSTGRK 121 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W R+I+ P FH + +++ + +F M+ + ++ A G +++ P D+ Sbjct: 122 WHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQS--RADGKTPINIFPVICLTALDI 179 Query: 723 ISRTAFGSNF----QEGMKIFQLQGELSERLIQAFQTLFIPGYWFF----PTKNNRRMRA 878 I+ TA G+ + Q +++ LI+ F + W F PT+ R+ +A Sbjct: 180 IAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKA 239 Query: 879 IDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQ--------SNGKANLGLSI 1034 I + + II ++ + N ++ + LS Sbjct: 240 I-KVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSD 298 Query: 1035 EDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG--RTTP-DFESL 1205 EDI +E F F G +TT+ +++ L +S HPE Q++ ++E+ G R +P L Sbjct: 299 EDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDL 358 Query: 1206 SRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGK 1385 LK + + E LRL+PP+ + R + +E+ G PAG N + I + DP+ + + Sbjct: 359 GELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYF-E 417 Query: 1386 DAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFS-FEL 1562 EF PERF + P A+ PF GPR CIGQ FA+ E K +S +L+ F L Sbjct: 418 SPDEFRPERFDADVPQI--HPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPL 475 Query: 1563 SPSYIHAPYTVITLQPQHGAQIRLK 1637 P H+ I L+ +G + LK Sbjct: 476 GPEPRHS--MNIVLRSANGVHLGLK 498
>O88833:CP4AA_MOUSE Cytochrome P450 4A10 - Mus musculus (Mouse)| Length = 509 Score = 139 bits (351), Expect = 3e-32 Identities = 113/435 (25%), Positives = 197/435 (45%), Gaps = 18/435 (4%) Frame = +3 Query: 393 WF-GPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN----GLANHEGEKWAKHR 557 WF G + V DP+ ++ IL ++ RLLA GL G+ W +HR Sbjct: 88 WFWGSKAYLTVYDPDYMKVILGRS-----DPKANGAYRLLAPWIGYGLLLLNGQPWFQHR 142 Query: 558 RILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTA 737 R+L PAFH++ +K + + M+ +WE +++ +T D + + A Sbjct: 143 RMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDS--SIEIFQHISLMTLDTVMKCA 200 Query: 738 F---GSNFQEGMKIFQLQ--GELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMI 902 F GS +G LQ G+L+ + +F + +N R+ ++ Sbjct: 201 FSHKGSVQVDGNYRTYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAKQACQLAHD 260 Query: 903 -LRGIIGKKERAIKNXXXXXXXXXXXXXXSN-----MQQSNGKANLGLSIEDIIQECKLF 1064 G+I ++ +++ + NG + +S +D+ E F Sbjct: 261 HTDGVIKLRKDQLQDEGELEKIKKKRRLDFLDILLFARMENGDS---MSDKDLRAEVDTF 317 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIFYE 1241 F G +TT+ ++W L+ HP+ Q++ REEV G ++ ++ L ++ TM E Sbjct: 318 MFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKE 377 Query: 1242 VLRLYPPITFLTRRTYKAMEL-GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFA 1418 LRLYPP+ + R ++ G P GV + L I +HH+P +W + F+P RFA Sbjct: 378 ALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVW-PNPEVFDPSRFA 436 Query: 1419 DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVI 1598 ++ + +F PF GG R CIG+ FA+ E K+ ++ L RF P+ + P + Sbjct: 437 P---DSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLARL 493 Query: 1599 TLQPQHGAQIRLKKI 1643 L+ ++G + LKK+ Sbjct: 494 VLKSKNGIYLHLKKL 508
>P11707:CP3A6_RABIT Cytochrome P450 3A6 - Oryctolagus cuniculus (Rabbit)| Length = 501 Score = 139 bits (349), Expect = 5e-32 Identities = 109/409 (26%), Positives = 197/409 (48%), Gaps = 10/409 (2%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK+ + G P +++ DP++++ +L + + F +RS + ++ E E Sbjct: 64 KKYGKMWGLFDGRQPLMVITDPDMIKTVLVKECYSVFTNRRSFGPVGFMKKAVSISEDED 123 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+P F K+K MLP+ + + ++ A+ VD+ F + DV Sbjct: 124 WKRVRTLLSPTFTSGKLKEMLPIIAQYGDVLVKNLRQE--AEKGKPVDLKEIFGAYSMDV 181 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSERLIQA--FQTLFIPGYWF---FPTKNNRRMRAIDR 887 I+ T+FG N + RL++ F L + F P + + Sbjct: 182 ITGTSFGVNIDSLRNPQDPFVKNVRRLLKFSFFDPLLLSITLFPFLTPIFEALHISMFPK 241 Query: 888 EIRMILRGIIGK-KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDI--IQECK 1058 ++ L+ + K K+ +K+ S Q++ + + +++DI + + Sbjct: 242 DVMDFLKTSVEKIKDDRLKDKQKRRVDFLQLMINS---QNSKEIDSHKALDDIEVVAQSI 298 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIF 1235 + FAG ETTS L++ + +L+ HP+ Q+K +EE+ + +++L +++ + M+ Sbjct: 299 IILFAGYETTSSTLSFIMHLLATHPDVQQKLQEEIDTLLPNKELATYDTLVKMEYLDMVV 358 Query: 1236 YEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 E LRLYP L R K +++ G P G +M+P +H DP W + EF PERF Sbjct: 359 NETLRLYPIAGRLERVCKKDVDINGTFIPKGTIVMMPTYALHRDPQHW-TEPDEFRPERF 417 Query: 1416 ADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + + P + PFG GPR C+G FAL K+AL ++Q FSF+L Sbjct: 418 SKKNKDNIN-PYIYHPFGAGPRNCLGMRFALMNIKLALVRLMQNFSFKL 465
>P49430:THAS_RAT Thromboxane-A synthase - Rattus norvegicus (Rat)| Length = 533 Score = 138 bits (347), Expect = 9e-32 Identities = 106/442 (23%), Positives = 194/442 (43%), Gaps = 41/442 (9%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIG-RLLANGLANHEGEK 542 + +G + + G +++ DP++++E+L F +F + ++ + +L+A+ + + Sbjct: 72 ERYGPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGLEPKLIADSVLMLRDRR 131 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R L AF EK+ M P+ S CE +++ ++S ++ ++ C + T +V Sbjct: 132 WEEVRGALMSAFSPEKLNEMTPLISQACELLLSHLKHSAASGDAFDIQRC--YCCFTTNV 189 Query: 723 ISRTAFGSNF-----------QEGMKIFQLQGELSE-RLIQAFQTLFIPGYWFFPTKNNR 866 ++ AFG Q ++F LI +F ++ +P P KN Sbjct: 190 VASVAFGIEVNSQDAPEDPFVQHCQRVFAFSTPRPLLALILSFPSIMVPLARILPNKNRD 249 Query: 867 RMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKAN--------- 1019 + ++R +I +++ +M +A Sbjct: 250 ELNGF---FNTLIRNVIALRDKQTAEERRGDFLQMVLDAQRSMSSVGVEAFDMVTEALSS 306 Query: 1020 ---LG--------------LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEK 1148 +G L++++I + LF AG E T+ L++ +L+ HPE QE+ Sbjct: 307 AECMGDPPQRCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQER 366 Query: 1149 AREEV-LHYFGRTTPDFESLSR-LKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYP 1322 +EV L P++ +L L + M+ E LR+YPP TR + E+ G P Sbjct: 367 LLKEVDLFMEKHPAPEYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCEVLGQHIP 426 Query: 1323 AGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNF 1502 AG L + + +HHDP+ W + F+PERF + ++P + PFG GPR C+G Sbjct: 427 AGSVLEIAVGALHHDPEHW-PNPETFDPERFT-AEARLQQKPFTYLPFGAGPRSCLGVRL 484 Query: 1503 ALQEAKMALSTILQRFSFELSP 1568 L K+ L +L +F FE P Sbjct: 485 GLLVVKLTLLQVLHKFRFEACP 506
>Q9V771:C6A23_DROME Probable cytochrome P450 6a23 - Drosophila melanogaster (Fruit fly)| Length = 502 Score = 138 bits (347), Expect = 9e-32 Identities = 123/464 (26%), Positives = 204/464 (43%), Gaps = 20/464 (4%) Frame = +3 Query: 312 PGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRS- 488 P HIA +T + + +F T ++ D ELV+ +L F HF + Sbjct: 47 PKKRHIAMIFRDYYTKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIF 106 Query: 489 -TRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSA 665 I L+ L + EG+KW R L P F K+K M P+ EEM + + Sbjct: 107 YNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTT 166 Query: 666 QGLCEVDVCPEFQNLTGDVISRTAFGSN---FQEGMKIFQLQGE--LSERLIQAFQTLFI 830 +++ T DVI AFG N Q F G+ + ER I Sbjct: 167 GEGQVLEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLI 226 Query: 831 PGYWFFPTKNNRRMRA------IDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSN 992 G+ K +RR+R ++ I+R I + R + Sbjct: 227 FGF----PKLSRRLRLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRHDFMDSLIEMYE--- 279 Query: 993 MQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHY 1172 ++ G GLS +I+ + +F+ AG ET+S + + L L++ + Q++ R E+ + Sbjct: 280 -KEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNV 338 Query: 1173 FGRTTPDF--ESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKY--PAGVNLM 1340 + +F E + +K + + E LR YP + LTR T KY G ++ Sbjct: 339 LSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVV 398 Query: 1341 LPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAK 1520 +P L IH+DP+I+ + +F PERF D + AA+ + PFG GPR CIG F L +A Sbjct: 399 IPALGIHYDPEIY-PEPEKFKPERFTDE-AIAARPSCTWLPFGEGPRNCIGLRFGLMQAC 456 Query: 1521 MALSTILQRFSFELS-PSYIHAPYTV--ITLQPQHGAQIRLKKI 1643 + L+ +++ + F +S + I + V I L ++G ++++K+ Sbjct: 457 VGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVEKL 500
>Q9DBW0:CP4V3_MOUSE Cytochrome P450 4V3 - Mus musculus (Mouse)| Length = 525 Score = 137 bits (346), Expect = 1e-31 Identities = 119/474 (25%), Positives = 196/474 (41%), Gaps = 24/474 (5%) Frame = +3 Query: 291 ARSQPMPPGSHHIAPRVLPMFTNAIK-----EHGKVSFTWFGPTPRVMVPDPELVREILS 455 AR+ P+ + ++ P F I H + W GP P V + E V IL+ Sbjct: 54 ARAYPLVGHALYMKPNNAEFFQQLIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILT 113 Query: 456 NKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEM 635 + + L GL G KW R++L P FH ++ L V + + Sbjct: 114 SSKQIDKSFLYKFLQPWLGLGLLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANIL 173 Query: 636 ITRWENSMSAQGLCEVDVCPEFQNLTG-DVISRTAFGSNF-------QEGMKIFQLQGEL 791 + + E ++ + C + L D+I TA G N E ++ ++ Sbjct: 174 VNKLEKHVNQEAFN----CFFYITLCALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDM 229 Query: 792 SERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXX 971 R ++ F W+ K R + + + +I ++ + K Sbjct: 230 IYRRMKMPWLWF--DLWYLVFKEGRDHKRGLKCLHTFTNNVIAERVKERKAEEDWTGAGR 287 Query: 972 XXXXXSNMQQS--------NGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSM 1127 N +++ + LS EDI +E F F G +TT+ + W+L +L Sbjct: 288 GPIPSKNKRKAFLDLLLSVTDEEGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGT 347 Query: 1128 HPEWQEKAREEVLHYFGRT--TPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAME 1301 +PE Q K +E+ FGR+ E L +LK + + E LR++P + R + E Sbjct: 348 NPEVQRKVDQELDEVFGRSHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCE 407 Query: 1302 LGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPR 1481 +GG K G ++ +H DP + D EF PERF ++ + P A+ PF GPR Sbjct: 408 VGGYKVTKGTEAIIIPYALHRDPRYF-PDPEEFRPERFFPE-NSQGRHPYAYVPFSAGPR 465 Query: 1482 ICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYT-VITLQPQHGAQIRLKK 1640 CIGQ FA+ E K L+ IL++F E + + L+P +G I+LK+ Sbjct: 466 NCIGQKFAVMEEKTILACILRQFWVESNQKREELGLAGDLILRPNNGIWIKLKR 519
>P36423:THAS_MOUSE Thromboxane-A synthase - Mus musculus (Mouse)| Length = 533 Score = 137 bits (345), Expect = 2e-31 Identities = 104/467 (22%), Positives = 201/467 (43%), Gaps = 44/467 (9%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIG-RLLANGLANHEGEK 542 + +G + + G V++ +P++++++L F +F + ++ + +++A+ + + Sbjct: 72 ERYGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGLEPKMVADSVLLLRDRR 131 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R L +F EK+ M P+ S CE ++ + +++ + C + T DV Sbjct: 132 WEEVRGALMSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAFNIQRC--YCCYTIDV 189 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSER------------LIQAFQTLFIPGYWFFPTKNNR 866 ++ AFG+ + R LI +F ++ +P P KN Sbjct: 190 VASVAFGTQVDSQNSPEDPFVQHCRRASTFCIPRPLLVLILSFPSIMVPLARILPNKNRD 249 Query: 867 RMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKA---------- 1016 + ++R +I +++ +M + Sbjct: 250 ELNGF---FNTLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSS 306 Query: 1017 ----------------NLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEK 1148 + ++++I+ + LF AG E + L++ +L+ HP+ QE+ Sbjct: 307 SECTKEPPQRCHPTSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQER 366 Query: 1149 AREEVLHYFGR-TTPDFESLSR-LKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYP 1322 +EV + G+ P++ SL L + M+ E LR+YPP TR + E+ G + P Sbjct: 367 LLKEVDLFMGKHPAPEYHSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQRIP 426 Query: 1323 AGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNF 1502 AG L + + +HHDP+ W + F+PERF + +RP + PFG GPR C+G Sbjct: 427 AGTVLEIAVGALHHDPEHW-PNPETFDPERFT-AEARLQRRPFTYLPFGAGPRSCLGVRL 484 Query: 1503 ALQEAKMALSTILQRFSFELSPSYIHAPYTV---ITLQPQHGAQIRL 1634 L K+ + +L +F FE SP P + L P++G I++ Sbjct: 485 GLLVVKLTILQVLHKFRFEASPE-TQVPLQLESKSALGPKNGVYIKI 530
>Q9VCW1:CP6D4_DROME Probable cytochrome P450 6d4 - Drosophila melanogaster (Fruit fly)| Length = 515 Score = 137 bits (345), Expect = 2e-31 Identities = 115/440 (26%), Positives = 196/440 (44%), Gaps = 29/440 (6%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHF---GKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAF 578 P V++ D +L R +L+ F F G L AN + + G+ W R +L+P F Sbjct: 78 PAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSAN-IFSLRGQSWRSMRHMLSPCF 136 Query: 579 HHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG---SN 749 K+K M ++M+ + + +G EVD+ QN D+I+ T FG ++ Sbjct: 137 TSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYAIDIIASTIFGLDVNS 196 Query: 750 FQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPT----------KNNRRMRAID----- 884 F+ F+ L+ R F +F + P+ KN + + Sbjct: 197 FENPDNKFRKLVSLA-RANNRFNAMFGMMIFLVPSIAQFLFRIGFKNPVGLAMLQIVKET 255 Query: 885 ---REIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQEC 1055 RE I+R + + ++N + K +S+E I + Sbjct: 256 VEYREKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPDGHIKT---ISLEAITAQA 312 Query: 1056 KLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD--FESLSRLKIVTM 1229 +FY AG ETT +T+ L+ +PE ++ ++EV + ++SL++++ + + Sbjct: 313 FIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDSLNKMEFLDL 372 Query: 1230 IFYEVLRLYPPITFLTRRTYKAMELGGIKY--PAGVNLMLPILFIHHDPDIWGKDAREFN 1403 E +R YP + L R + + + P G +++ + IHHD + + D ++ Sbjct: 373 CVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYF-PDPETYD 431 Query: 1404 PERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE-LSPSYIH 1580 PERF++ N P AF PFG GPRICI Q +K+A+ ILQ F+ E +S S I Sbjct: 432 PERFSEESRNY--NPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIE 489 Query: 1581 APYTVITLQPQHGAQIRLKK 1640 + I L P+HG ++RL K Sbjct: 490 FENSGIALIPKHGVRVRLSK 509
>Q64581:CP3AI_RAT Cytochrome P450 3A18 - Rattus norvegicus (Rat)| Length = 497 Score = 136 bits (343), Expect = 3e-31 Identities = 108/414 (26%), Positives = 187/414 (45%), Gaps = 16/414 (3%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK+ + GP P + + DPE+++ +L + + F +R + + E E+ Sbjct: 66 KKYGKIWGFYEGPQPFLAIMDPEIIKMVLVKECYSVFTNRRCFGPMGFMKKAITMSEDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R IL+P F K+K M P+ + ++ A+G +++ F + DV Sbjct: 126 WKRLRTILSPTFTSGKLKEMFPLMRQYGDTLLKNLRRE-EAKGE-PINMKDIFGAYSMDV 183 Query: 723 ISRTAFGSNF-----------QEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRR 869 I+ T+FG N Q+ KI + Q + F + + P Sbjct: 184 ITGTSFGVNVDSLNNPQDPFVQKAKKILKFQ------IFDPFLLSVVLFPFLTPIYEMLN 237 Query: 870 MRAIDREIRMILRGIIG--KKERAIKNXXXXXXXXXXXXXXSNMQQSNGK-ANLGLSIED 1040 R+ + + KK R N N Q S G+ + LS + Sbjct: 238 FSIFPRQSMNFFKKFVKTMKKNRLDSNQKNRVDFLQLMM---NTQNSKGQESQKALSDLE 294 Query: 1041 IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSRLK 1217 + + +F F G + TS +++ + L+ P Q+K + E+ P +++L ++ Sbjct: 295 MAAQAIIFIFGGYDATSTSISFIMYELATRPNVQKKLQNEIDRALPNKAPVTYDALMEME 354 Query: 1218 IVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDARE 1397 + M+ E LRLYP T L R + K +E+ G+ P G + +PI +H +P+ W + E Sbjct: 355 YLDMVVNESLRLYPIATRLDRVSKKDVEINGVFIPKGTVVTIPIYPLHRNPEYW-LEPEE 413 Query: 1398 FNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 FNPERF+ + + P + PFG GPR CIG FAL K+A+ +LQ F+ + Sbjct: 414 FNPERFSKE-NKGSIDPYVYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFNIQ 466
>Q9VA27:CP4C3_DROME Cytochrome P450 4c3 - Drosophila melanogaster (Fruit fly)| Length = 535 Score = 135 bits (341), Expect = 4e-31 Identities = 108/422 (25%), Positives = 185/422 (43%), Gaps = 29/422 (6%) Frame = +3 Query: 381 VSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRR 560 ++ W G PRV++ +PE V IL+++ + L GL KW R+ Sbjct: 97 INRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWLGEGLLTSTDRKWHSRRK 156 Query: 561 ILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAF 740 IL PAFH + + + VF+ + + + ++ ++ P T D++ TA Sbjct: 157 ILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAF---NLFPYVTLCTLDIVCETAM 213 Query: 741 GSNFQEGMKIFQLQGELSE---------RLIQAFQT-LFIPGYWFFPTKNNRRMR----- 875 G +I+ SE ++Q+ Q +++ + F ++ Sbjct: 214 ------GRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYIN 267 Query: 876 AIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSI------- 1034 + M++R K E AI ++ + A L L I Sbjct: 268 TLHGFSNMVIRE--RKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKEGT 325 Query: 1035 ----EDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG---RTTPD 1193 EDI +E F F G +TTS ++WTL +L HPE+QE+ EE+ FG T Sbjct: 326 VLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPAT 385 Query: 1194 FESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPD 1373 ++L ++ + + LRL+P + + R + + +GG PAG ++ +H +P Sbjct: 386 MKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPR 445 Query: 1374 IWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFS 1553 ++ K +FNP+ F + A + P A+ PF GPR CIGQ FA+ E K +ST+L+++ Sbjct: 446 VFPK-PEQFNPDNFLPE-NCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYK 503 Query: 1554 FE 1559 E Sbjct: 504 IE 505
>Q9V7G5:C4AA1_DROME Probable cytochrome P450 4aa1 - Drosophila melanogaster (Fruit fly)| Length = 514 Score = 135 bits (341), Expect = 4e-31 Identities = 112/437 (25%), Positives = 194/437 (44%), Gaps = 14/437 (3%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRI-GRLLANGLANHEGEKWA 548 +G + W P V +PE ++ ILS+K H K R+ L +GL G KW+ Sbjct: 84 YGSLVRIWVLLFPFFAVLEPEDLQVILSSK-KHTNKVFFYRLMHNFLGDGLITSSGSKWS 142 Query: 549 KHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVIS 728 HRR++ PAFHH +++ + F + + +EN + E+++ N D+++ Sbjct: 143 NHRRLIQPAFHHNLLEKFIDTFVDASQSL---YENLDAEAVGTEINIAKYVNNCVLDILN 199 Query: 729 RTAFGSNFQE-GMKIFQL------QGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDR 887 G ++ G + + QG++ L + G + + N + + Sbjct: 200 EAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMANDELNQ-KK 258 Query: 888 EIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFY 1067 + R +I ++ + N + +S N + EDI+ E F Sbjct: 259 RLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISES----NRDFTEEDIVNEACTFM 314 Query: 1068 FAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF--GRTTPDFESLSRLKIVTMIFYE 1241 AG ++ + +TL +L+ +PE Q++ E+ F P L ++ + M E Sbjct: 315 LAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKE 374 Query: 1242 VLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFAD 1421 LRLYP + + R+ + + L PAG N+ + H I+ D +F PERF+ Sbjct: 375 ALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIY-PDPEKFQPERFSP 433 Query: 1422 GISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSP----SYIHAPY 1589 ++ + P AF PF GPR CIG FA+ E K +S +L+ S++L P + I A + Sbjct: 434 E-NSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLR--SYQLLPVTGKTTIAATF 490 Query: 1590 TVITLQPQHGAQIRLKK 1640 ITL+ G +RLK+ Sbjct: 491 R-ITLRASGGLWVRLKE 506
>O09158:CP3AP_MOUSE Cytochrome P450 3A25 - Mus musculus (Mouse)| Length = 503 Score = 135 bits (339), Expect = 8e-31 Identities = 105/409 (25%), Positives = 187/409 (45%), Gaps = 11/409 (2%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK+ + GP P + + DPE+++ +L + + F +R + + E E+ Sbjct: 66 KKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFMKKAITISEDEE 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMS-AQGLCEVDVCPEFQNLTGD 719 W + R +L+P F K+K M P+ + ++ + + D+ F + D Sbjct: 126 WKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDI---FGAYSMD 182 Query: 720 VISRTAFGSNFQ-----EGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAID 884 VI+ T+FG N + + + + L ++ F I + P Sbjct: 183 VITGTSFGVNVDSLNNPQDPFVQKAKKILKFKIFDPFLLSIILFPFLTPIYEMLNFSIFP 242 Query: 885 REIRMILRGIIG--KKERAIKNXXXXXXXXXXXXXXSNMQQSNGK-ANLGLSIEDIIQEC 1055 R+ + + KKER N N Q S G+ + LS ++ + Sbjct: 243 RDSMNFFKKFVKRMKKERLASNQKNRVDFLQLMM---NTQNSKGQESQKALSDLEMAAQA 299 Query: 1056 KLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSRLKIVTMI 1232 +F F G + TS ++ + L+ HP+ Q+K ++E+ P +++L ++ + M+ Sbjct: 300 VIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMV 359 Query: 1233 FYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 E LRLYP L R + K +E+ G+ P G +M+PI +H +P+ W + +EF PER Sbjct: 360 VNESLRLYPIAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYW-PEPQEFCPER 418 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 F+ + P + PFG GPR CIG FAL K+A+ +LQ F+ + Sbjct: 419 FSKE-NKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQ 466
>Q64406:CP3AF_CAVPO Cytochrome P450 3A15 - Cavia porcellus (Guinea pig)| Length = 503 Score = 134 bits (338), Expect = 1e-30 Identities = 110/429 (25%), Positives = 190/429 (44%), Gaps = 21/429 (4%) Frame = +3 Query: 333 PRVLPMFTNAI--------------KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FG 467 P+ LP+F N + K++G + + GP P + + +P++++ +L + + Sbjct: 41 PKPLPLFGNVLSYRKGMWSFDIECRKKYGNMWGLYDGPQPVLAITEPDMIKAVLVKECYS 100 Query: 468 HFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRW 647 F +RS + ++ E E+W + R L+P F K+K M P+ + ++ Sbjct: 101 VFTNRRSLVPVGFMKKSVSLSEDEEWKRIRTQLSPNFTSGKLKEMFPIIKQYGDVLVKNL 160 Query: 648 ENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQA-FQTL 824 A+ V + F D+I TAFG N + +L + F + Sbjct: 161 RQE--AEKGKPVQLKEIFGAYGMDIIIATAFGVNVDSLNNPHDPFVSKANKLFRFDFLSP 218 Query: 825 FIPGYWFFPTKNNR-RMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQ 1001 F+ FP M +I R L+ ++ +N + Sbjct: 219 FLLSTVMFPFLTQLYEMLSISIFPRDSLKFFTKFVKKTKENHLESNKKQRVNFLQMMLNS 278 Query: 1002 SNGK---ANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHY 1172 N K ++ LS +I+ + +F FAG ET+S L+ + L+ HP+ Q+K +E+ Sbjct: 279 QNFKDTESHKALSDVEILAQSIIFIFAGYETSSSTLSCIMYSLATHPDVQKKLHQEIDKT 338 Query: 1173 F-GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPI 1349 + P ++ + ++ + M+ E LRLYP + R + K E+ G+ +P G +M+P Sbjct: 339 LPNKAFPTYDVMMEMEYLDMVVNETLRLYPVANRIERMSKKDFEINGMSFPKGTLVMIPS 398 Query: 1350 LFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMAL 1529 +H D W + EF PERF+ + P + PFG GPR CIG+ AL K+AL Sbjct: 399 FALHRDSKYW-PEPDEFRPERFSKK-NKENIDPYIYMPFGNGPRNCIGRRMALMNLKLAL 456 Query: 1530 STILQRFSF 1556 +LQ FSF Sbjct: 457 IRLLQNFSF 465
>O17624:C13B1_CAEEL Putative cytochrome P450 cyp-13B1 - Caenorhabditis elegans| Length = 527 Score = 134 bits (338), Expect = 1e-30 Identities = 107/423 (25%), Positives = 192/423 (45%), Gaps = 28/423 (6%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRI--GRLLAN------GL 521 ++ GKV + G P ++V D ++++E+ KF +F ++ST G L + L Sbjct: 61 QKFGKVFGYYEGAVPVLVVSDMDMLQELFLKKFDNFYARKSTNHIHGNLECSKSEPRINL 120 Query: 522 ANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEF 701 G +W + R + +P F + +K++ V M+ + ++ F Sbjct: 121 FTSRGARWKRLRALASPGFSVKALKQVHDVMEDSAINMVDLMAKHEDGKPF---NIHAYF 177 Query: 702 QNLTGDVISRTAFGSNFQE-----GMKIFQLQGELSERLIQAFQTLFIPGYWFFPTK--- 857 Q T DVISR A G E G++I + + R++ + T+ P + + Sbjct: 178 QEFTYDVISRLAMGQPNSELFNNSGVEIVKSIFMRTHRVLPWYFTVLFPQFEHLVKRMFY 237 Query: 858 NNRRMRAIDREIRMIL-----RGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANL 1022 N+ ++ D E +++ I ++E K + + Sbjct: 238 NHAAVQGGDIEKLLLICKKTVESRIQEREENAKLGFENAENDFIDMFLNYYSEQVEDIEF 297 Query: 1023 GLSIE------DIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRT 1184 G ++E D+I C +F AG +TT+ L + +L+ HPE + A+EEV G Sbjct: 298 GSTVEKKVTAEDVIGACFVFLLAGFDTTANSLAYASYLLAKHPEKMKLAQEEVDTVVGSE 357 Query: 1185 TPDFESLSRLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLMLPILFIH 1361 ++ +++LK + + E LRLYP F +R K LG I GV + ++ +H Sbjct: 358 NVSYDDMTKLKYLDAVVRESLRLYPVAWFACSRECVKPTTLGDIYIDKGVKIEADVMSLH 417 Query: 1362 HDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTIL 1541 +IWG++A +F PER+ + +++ ++ PFG GPR C+G L EAK AL+ +L Sbjct: 418 RSKEIWGENADDFVPERW---LEPSSRHTMSWIPFGAGPRQCVGMRLGLSEAKTALAHLL 474 Query: 1542 QRF 1550 +R+ Sbjct: 475 RRY 477
>Q9VGB3:CP133_DROME Probable cytochrome P450 313a3 - Drosophila melanogaster (Fruit fly)| Length = 492 Score = 134 bits (336), Expect = 2e-30 Identities = 111/430 (25%), Positives = 189/430 (43%), Gaps = 17/430 (3%) Frame = +3 Query: 336 RVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREI-LSNKFGHFGKQRSTRIGRLLA 512 R + + T + +G W GPTP V+ DP++ EI LS + + S + Sbjct: 53 RKMSIRTKYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTG 112 Query: 513 NGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVC 692 +GL + E KW R+ LNPAF + LP+F++ + ++ + +S+ QG E V Sbjct: 113 DGLLSLEASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVA-FLDSLVGQG--EKKVR 169 Query: 693 PEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLF--IPGYWFFPTKNNR 866 + + + ++T G++ ++ ++ ++++++T I P +N+ Sbjct: 170 DDIVRWSFRIATQTTVGTDVKKDASF------KNDSVLKSYETFMKIIVMNVLLPFTHNK 223 Query: 867 ---------RMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKAN 1019 +A+ + + G I K+ K + NG+ Sbjct: 224 IFSTLGGFETQKALAKSNVNKMIGTIVDKKLMTKPESGSQPEITSVINKAIELHRNGE-- 281 Query: 1020 LGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF---GRTTP 1190 +S E++ EC F A ETT + LI+L+M PE Q+ +E+ F G Sbjct: 282 --MSREEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEV 339 Query: 1191 DFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELG-GIKYPAGVNLMLPILFIHHD 1367 ++ L R+ + + E LRL P + F R T + L G+ P GV + + I H + Sbjct: 340 TYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRN 399 Query: 1368 PDIWGKDAREFNPERFA-DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQ 1544 D WG D FNP+ F D + + + P A+ PF G R CIG + L +K+ALS IL+ Sbjct: 400 RDHWGTDPSSFNPDHFLPDNVRD--RHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILR 457 Query: 1545 RFSFELSPSY 1574 S Y Sbjct: 458 NCKVSTSFRY 467
>P24557:THAS_HUMAN Thromboxane-A synthase - Homo sapiens (Human)| Length = 533 Score = 133 bits (335), Expect = 2e-30 Identities = 107/464 (23%), Positives = 205/464 (44%), Gaps = 41/464 (8%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIG-RLLANGLANHEGEK 542 K +G + + G +++ +P++++++L F +F + ++ + + +A+ + ++ Sbjct: 72 KLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRDKR 131 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R L AF EK+ M+P+ S C+ ++ + + ++ C + N T DV Sbjct: 132 WEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRC--YCNYTTDV 189 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSER------------LIQAFQTLFIPGYWFFPTKNN- 863 ++ FG+ + +R L+ +F ++ +P P KN Sbjct: 190 VASVPFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRD 249 Query: 864 ----------------RRMRAIDREIRMILRGIIGKKERA----IKNXXXXXXXXXXXXX 983 R +A + R L+ ++ + A +++ Sbjct: 250 ELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGC 309 Query: 984 XSNMQQSNGKANLG--LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKARE 1157 N + + + + L++++I+ + +F AG E + L++ +L+ +P+ QEK Sbjct: 310 KPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLR 369 Query: 1158 EVLHYFGR-TTPDFESLSR-LKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGV 1331 EV + + P+F SL L + M+ E LR+YPP TR + E+ G + PAG Sbjct: 370 EVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA 429 Query: 1332 NLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQ 1511 L + + +HHDP+ W FNPERF + RP + PFG GPR C+G L Sbjct: 430 VLEMAVGALHHDPEHW-PSPETFNPERFT-AEARQQHRPFTYLPFGAGPRSCLGVRLGLL 487 Query: 1512 EAKMALSTILQRFSFELSPSYIHAPYTV---ITLQPQHGAQIRL 1634 E K+ L +L +F F+ P P + L P++G I++ Sbjct: 488 EVKLTLLHVLHKFRFQACPE-TQVPLQLESKSALGPKNGVYIKI 530
>Q64409:CP3AH_CAVPO Cytochrome P450 3A17 - Cavia porcellus (Guinea pig)| Length = 503 Score = 133 bits (334), Expect = 3e-30 Identities = 110/429 (25%), Positives = 187/429 (43%), Gaps = 21/429 (4%) Frame = +3 Query: 333 PRVLPMFTNAI--------------KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FG 467 P+ LP+F N + K++G + + GP P + + +P++++ +L + + Sbjct: 41 PKPLPLFGNVLSYRKGIWNFDIECHKKYGNMWGLYDGPRPVLSITEPDMIKAVLVKECYS 100 Query: 468 HFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRW 647 F +RS + L+ + E+W + R L+ F K+K M P+ + ++ Sbjct: 101 VFTNRRSIFPAGFMKKALSISKDEEWKRIRTQLSQNFTSGKLKEMFPIIKQYGDVLVKNL 160 Query: 648 ENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQA-FQTL 824 A+ V + F + D+I TAFG N + +L + F + Sbjct: 161 RQE--AEKGKPVQLKEIFGAYSMDIIIATAFGVNVDSLNNPHDPFVSKASKLFRFDFLSP 218 Query: 825 FIPGYWFFPTKNNR-RMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQ 1001 F+ FP M I R L +R +N ++ Sbjct: 219 FLLSVVIFPFLTQLYEMLNISIFPRDSLNFFTKFVKRTKENHLESNEKQRVNFLQMMLKS 278 Query: 1002 SNGK---ANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHY 1172 N K ++ LS +I+ + F AG ETTS L + + L+ HP+ Q+K ++E+ Sbjct: 279 QNFKDTESHKALSDVEILAQSIFFIVAGYETTSSTLCFIMYSLATHPDVQKKLQQEIDKT 338 Query: 1173 F-GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPI 1349 + P ++ + ++ + M+ E LRLYP + R + K E+ G+ +P G +M+P Sbjct: 339 LPNKAFPTYDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKDFEINGMSFPKGTGVMIPS 398 Query: 1350 LFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMAL 1529 +H D W + EF PERF+ + P + PFG GPR CIG AL K+AL Sbjct: 399 FALHRDSKYW-PEPDEFRPERFSKK-NKENIDPYIYMPFGNGPRNCIGMRMALMNLKLAL 456 Query: 1530 STILQRFSF 1556 +LQ FSF Sbjct: 457 IRLLQNFSF 465
>P33269:CP4D1_DROME Cytochrome P450 4d1 - Drosophila melanogaster (Fruit fly)| Length = 512 Score = 132 bits (333), Expect = 4e-30 Identities = 117/470 (24%), Positives = 194/470 (41%), Gaps = 38/470 (8%) Frame = +3 Query: 309 PPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRS 488 PP H + ++ K+ +V W GP V++ +P+ V +L + Sbjct: 53 PP--HEMVKKIFEFMETYSKD--QVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEY 108 Query: 489 TRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQ 668 + L GL G KW K R+I+ PAFH + + + + VF +++ E Sbjct: 109 KALEPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKH 168 Query: 669 GLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTL-------- 824 G + T D I TA G + Q +QA +T+ Sbjct: 169 GESGFSLYDWINLCTMDTICETAMGVSINA-------QSNADSEYVQAVKTISMVLHKRM 221 Query: 825 ------FIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXX 986 F Y P + +A++ + + I+ ++E I+ Sbjct: 222 FNILYRFDLTYMLTPLARAEK-KALNVLHQFTEKIIVQRREELIREG------------- 267 Query: 987 SNMQQSNGKANLG--------------------LSIEDIIQECKLFYFAGMETTSVLLTW 1106 S+ + SN A++G LS DI +E F F G +TTS L + Sbjct: 268 SSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMF 327 Query: 1107 TLIVLSMHPEWQEKAREEVLHYFG--RTTP-DFESLSRLKIVTMIFYEVLRLYPPITFLT 1277 ++ HPE Q+K EE+ G ++TP +E L++L V + E LR+YP + L Sbjct: 328 FFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLG 387 Query: 1278 RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAK-RPAA 1454 R+ + E+ G PAG N+ + L++ +++ + F PERF D ++ A K P A Sbjct: 388 RKVLEDCEINGKLIPAGTNIGISPLYLGRREELFS-EPNSFKPERF-DVVTTAEKLNPYA 445 Query: 1455 FFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITL 1604 + PF GPR CIGQ FA+ E K ++ +L+ + + P + L Sbjct: 446 YIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAEL 495
>Q964T2:CP9E2_BLAGE Cytochrome P450 9e2 - Blattella germanica (German cockroach)| Length = 533 Score = 132 bits (332), Expect = 5e-30 Identities = 119/441 (26%), Positives = 198/441 (44%), Gaps = 56/441 (12%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQR---STRIGRLLANGLANHEGEKWAKHRRILNPAF 578 P +++ DPEL++ + F +F R S + L N G +W + R L+PAF Sbjct: 84 PVLVLRDPELIKMVTVKDFEYFLDHRAPISEEAEPMFGKNLFNLRGHRWKEMRSTLSPAF 143 Query: 579 HHEKIKRMLPVFSACCEEM------ITRWENS------MSAQG-LCEVDVCPEFQNLTGD 719 K+K M + S C +++ +R +N + +G L V++ + T D Sbjct: 144 TSSKMKNMFVLVSECGKQLGEFLMECSRDKNKKTEGCKIEREGDLLTVELKDLYTRYTND 203 Query: 720 VISRTAFGSN-----------FQEGMKIFQLQGE---------LSERLIQAFQTLFIPG- 836 VI+ +AFG FQ G + G S RL++ F+ Sbjct: 204 VIATSAFGIGCDSLKNPKNEFFQMGKDVTNFGGIRQFIFLGYLFSPRLMKYLNLKFLSSK 263 Query: 837 ------YWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQ 998 + T + R+ + I R + L ++ KE +K+ Sbjct: 264 ATEFFRFLVHNTMDTRKTKGIIRPDMIHL--LMQAKEGTLKS------------------ 303 Query: 999 QSNGKANLGLSI------EDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREE 1160 + NG+ N ++ +D+ + LF+FAG +T S LL + +L+ +P+ Q + ++E Sbjct: 304 EENGETNGKIASKPKWDDDDLTAQAVLFFFAGFDTASTLLCFMSHLLATNPDVQNRLQDE 363 Query: 1161 VLHYF----GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELG---GIKY 1319 + G+ T +E++ +K + M+ E LRLYPP F R+ K L Sbjct: 364 IDQSLEENDGKLT--YEAIHSMKYLDMVVSESLRLYPPAIFTDRKCVKNYRLPMEPSYTL 421 Query: 1320 PAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQN 1499 G + +PI IHHDP + + +F+PERF+D + K P + PFG GPR CIG Sbjct: 422 EPGDAVWIPIYAIHHDPKYY-PNPEKFDPERFSDENKDNIK-PFTYLPFGSGPRNCIGNR 479 Query: 1500 FALQEAKMALSTILQRFSFEL 1562 FAL E+K+AL +L RF+ ++ Sbjct: 480 FALMESKIALVHLLCRFNLKV 500
>Q9PVE8:C330_FUNHE Cytochrome P450 3A30 - Fundulus heteroclitus (Killifish) (Mummichog)| Length = 496 Score = 132 bits (331), Expect = 6e-30 Identities = 101/406 (24%), Positives = 182/406 (44%), Gaps = 7/406 (1%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GKV + G P + V DPE+++ +L + F +R+ R+ L + ++ E ++ Sbjct: 65 KKYGKVWGIYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNFRLNGPLYDAVSIAEDDQ 124 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+P+F ++K M + +I + +D+ F + + DV Sbjct: 125 WKRIRSVLSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKDE--PLDLKEFFGSYSMDV 182 Query: 723 ISRTAFGSNFQE-GMKIFQLQGELSERLIQAFQTLFIPGYWFFP----TKNNRRMRAIDR 887 ++ TAF + + + L F FFP + + Sbjct: 183 VTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLAVAFFPFLGPILEKFELSFFPK 242 Query: 888 EIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFY 1067 + + K + + + + S + + L+ +I+ + +F Sbjct: 243 SVTDFFYASLEKIKSNREASQQKSRVDFLQLMIDSQKNSGAQQDKSLTDHEILSQSMIFI 302 Query: 1068 FAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSRLKIVTMIFYEV 1244 FAG ET+S LT+ L+ +PE +K +EE+ F P ++ L ++ + + E Sbjct: 303 FAGYETSSSSLTFLAYNLATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINES 362 Query: 1245 LRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADG 1424 LRL+P L R A+E+ G+ P + +M+P +H DP+IW + F PERF+ Sbjct: 363 LRLFPIAARLERVAKAAVEINGVVIPKDMVVMIPTWPLHRDPEIW-PEPEAFKPERFSKK 421 Query: 1425 ISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + P + PFG GPR CIG FAL K+A+ ILQ++SF + Sbjct: 422 NKDNID-PYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>Q8AXY5:C356_FUNHE Cytochrome P450 3A56 - Fundulus heteroclitus (Killifish) (Mummichog)| Length = 496 Score = 131 bits (330), Expect = 8e-30 Identities = 102/406 (25%), Positives = 181/406 (44%), Gaps = 7/406 (1%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GKV + G P + V DPE+++ +L + F +R+ + L + L+ E ++ Sbjct: 65 KKYGKVWGIYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNFHLNGPLYDALSVAEDDQ 124 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+P+F ++K M + +I + +D+ F + + DV Sbjct: 125 WKRIRSVLSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKDE--PLDLKEFFGSYSMDV 182 Query: 723 ISRTAFGSNFQE-GMKIFQLQGELSERLIQAFQTLFIPGYWFFP----TKNNRRMRAIDR 887 ++ TAF + + + L F FFP + + Sbjct: 183 VTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLAVAFFPFLGPILEKFELSFFPK 242 Query: 888 EIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFY 1067 + + K + + + + S + + L+ +I+ + +F Sbjct: 243 SVTDFFYASLEKIKSNREASQQKSRVDFLQLMIDSQKNSGAQQDKSLTDHEILSQSMIFI 302 Query: 1068 FAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSRLKIVTMIFYEV 1244 FAG ET+S LT+ L+ +PE +K +EE+ F P ++ L ++ + + E Sbjct: 303 FAGYETSSSSLTFLAYNLATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINES 362 Query: 1245 LRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADG 1424 LRL+P L R A+E+ GI P + +M+P +H DP+IW + F PERF+ Sbjct: 363 LRLFPIAARLERVAKAAVEINGIVIPKDMVVMIPTWPLHRDPEIW-PEPEAFKPERFSKK 421 Query: 1425 ISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + P + PFG GPR CIG FAL K+A+ ILQ++SF + Sbjct: 422 NKDNID-PYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>O16805:CP4D1_DROSI Cytochrome P450 4d1 - Drosophila simulans (Fruit fly)| Length = 512 Score = 130 bits (326), Expect = 2e-29 Identities = 116/470 (24%), Positives = 193/470 (41%), Gaps = 38/470 (8%) Frame = +3 Query: 309 PPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRS 488 PP H + ++ K+ +V W GP V++ +P+ V +L + Sbjct: 53 PP--HEMVKKIFEFMETYSKD--QVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEY 108 Query: 489 TRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQ 668 + L GL G KW K R+I+ PAFH + + + + VF +++ E Sbjct: 109 KALEPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVDVFEKGSRDLLRNMEQDRLKH 168 Query: 669 GLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTL-------- 824 G + T D I TA G + Q +QA +T+ Sbjct: 169 GDSGFSLYDWINLCTMDTICETAMGVSINA-------QSNADSEYVQAVKTISMVLHKRM 221 Query: 825 ------FIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXX 986 F Y P + +A++ + + I+ ++E I+ Sbjct: 222 FNILYRFDLTYMLTPLARAEK-KALNVLHQFTEKIIVQRREELIREG------------- 267 Query: 987 SNMQQSNGKANLG--------------------LSIEDIIQECKLFYFAGMETTSVLLTW 1106 S+ + S A++G LS DI +E F F G +TTS L + Sbjct: 268 SSQESSKDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMF 327 Query: 1107 TLIVLSMHPEWQEKAREEVLHYFG--RTTP-DFESLSRLKIVTMIFYEVLRLYPPITFLT 1277 ++ HPE Q+K EE+ G ++TP +E L++L V + E LR+YP + L Sbjct: 328 FFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLG 387 Query: 1278 RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAK-RPAA 1454 R+ + E+ G PAG N+ + L++ +++ + F PERF D ++ A K P A Sbjct: 388 RKVLEDCEINGKLIPAGTNIGISPLYLGRREELFS-EPNSFKPERF-DVVTTAEKLNPYA 445 Query: 1455 FFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITL 1604 + PF GPR CIGQ FA+ E K ++ +L+ + + P + L Sbjct: 446 YIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAEL 495
>Q6ZWL3:CP4V2_HUMAN Cytochrome P450 4V2 - Homo sapiens (Human)| Length = 525 Score = 129 bits (325), Expect = 3e-29 Identities = 109/434 (25%), Positives = 182/434 (41%), Gaps = 18/434 (4%) Frame = +3 Query: 393 WFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNP 572 W GP P V + + E V IL++ + L GL G KW R++L P Sbjct: 93 WVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTP 152 Query: 573 AFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTG-DVISRTAFGSN 749 FH ++ L + + ++ + E ++ + C + L D+I TA G N Sbjct: 153 TFHFTILEDFLDIMNEQANILVKKLEKHINQEAFN----CFFYITLCALDIICETAMGKN 208 Query: 750 F----QEGMKIFQLQGELSERLIQAFQTLFI-PGYWFFPTKNNRRMRAIDREIRMILRGI 914 + + + +SE + + + ++ W+ K + + + + Sbjct: 209 IGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSV 268 Query: 915 IGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLG--------LSIEDIIQECKLFYF 1070 I ++ + N +++ L LS EDI +E F F Sbjct: 269 IAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMF 328 Query: 1071 AGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTT--PDFESLSRLKIVTMIFYEV 1244 G +TT+ + W+L +L +PE Q+K E+ FG++ E L +L+ + + E Sbjct: 329 EGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKET 388 Query: 1245 LRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADG 1424 LRL+P + R + E+ G + G ++ +H DP + + EF PERF Sbjct: 389 LRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFP- 446 Query: 1425 ISNAAKR-PAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYT-VI 1598 NA R P A+ PF GPR CIGQ FA+ E K LS IL+ F E + + Sbjct: 447 -ENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQL 505 Query: 1599 TLQPQHGAQIRLKK 1640 L+P +G I+LK+ Sbjct: 506 ILRPSNGIWIKLKR 519
>Q9VYQ7:CP311_DROME Probable cytochrome P450 311a1 - Drosophila melanogaster (Fruit fly)| Length = 483 Score = 129 bits (325), Expect = 3e-29 Identities = 103/389 (26%), Positives = 177/389 (45%), Gaps = 10/389 (2%) Frame = +3 Query: 504 LLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEV 683 L+ NGL G W + RR+L PAF + ++ P E ++ R + A EV Sbjct: 106 LIGNGLLISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGA--FLEV 163 Query: 684 DVCPEFQNLTGDVISRTAFGSNFQ----EGMKIFQLQGELSERLIQAFQTLFIPGYWFFP 851 P F L D I T+ G+ + I Q S+ L + + W F Sbjct: 164 TE-PLFACLL-DAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIF- 220 Query: 852 TKNNRRMRAIDREIRMI---LRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANL 1022 + + R +D ++++I + +I K+ + + + + + G++ Sbjct: 221 -QRTQLWRDLDEQLQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLDTLLLAKFEGQS-- 277 Query: 1023 GLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFES 1202 LS +I E F FAG++TT+ +++ L L+ PE Q + R+E+ T D ++ Sbjct: 278 -LSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLDA 336 Query: 1203 LSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWG 1382 L+ L + + EVLRLY + R+T ++ E+GG Y AGV L + + + HD + + Sbjct: 337 LNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYY- 395 Query: 1383 KDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 D F PER+ A ++ PF GGP +CIG+ ++L K+ + +++ F EL Sbjct: 396 PDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMEL 455 Query: 1563 SPSYIHAPYTV---ITLQPQHGAQIRLKK 1640 SP AP + + L+ Q G + K Sbjct: 456 SPE--QAPLRLEAQMVLKAQQGINVSFLK 482
>Q5RCN6:CP4V2_PONPY Cytochrome P450 4V2 - Pongo pygmaeus (Orangutan)| Length = 525 Score = 129 bits (323), Expect = 5e-29 Identities = 109/434 (25%), Positives = 181/434 (41%), Gaps = 18/434 (4%) Frame = +3 Query: 393 WFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNP 572 W GP P V + + E V IL++ + L GL G KW R++L P Sbjct: 93 WVGPVPMVALYNAENVEVILTSSRQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTP 152 Query: 573 AFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTG-DVISRTAFGSN 749 FH ++ L + + ++ + E ++ + C + L D+I TA G N Sbjct: 153 TFHFTILEDFLDIMNEQANILVKKLEKHVNQEAFN----CFFYITLCALDIICETAMGKN 208 Query: 750 F----QEGMKIFQLQGELSERLIQAFQTLFI-PGYWFFPTKNNRRMRAIDREIRMILRGI 914 + + + +S+ + Q + ++ W+ K + + + Sbjct: 209 IGAQSNDDSEYVRAVYRMSQMIFQRIKMPWLWLDLWYLMFKEGWEHEKGLKILHTFTNNV 268 Query: 915 IGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLG--------LSIEDIIQECKLFYF 1070 I ++ + N +++ L LS EDI +E F F Sbjct: 269 IAERANEMNADEDCRGVGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMF 328 Query: 1071 AGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTT--PDFESLSRLKIVTMIFYEV 1244 G +TT+ + W+L +L +PE Q+K E+ FG++ E L +L+ + + E Sbjct: 329 EGHDTTAAAINWSLYLLGCNPEVQQKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKET 388 Query: 1245 LRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADG 1424 LRL+P + R + E+ G + G ++ +H DP + + EF PERF Sbjct: 389 LRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFP- 446 Query: 1425 ISNAAKR-PAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYT-VI 1598 NA R P A+ PF GPR CIGQ FA+ E K LS IL+ F E + + Sbjct: 447 -ENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQL 505 Query: 1599 TLQPQHGAQIRLKK 1640 L+P +G I+LK+ Sbjct: 506 ILRPSNGIWIKLKR 519
>O18596:C4D10_DROMT Cytochrome P450 4d10 - Drosophila mettleri (Fruit fly)| Length = 513 Score = 129 bits (323), Expect = 5e-29 Identities = 108/400 (27%), Positives = 181/400 (45%), Gaps = 22/400 (5%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 L +GL G KW + R+I+ PAFH ++ +F +I +W+ ++ D Sbjct: 122 LNDGLLLSGGRKWHRRRKIITPAFHFRILESYDEIFDRQTRLLIHKWQQTLGHS----FD 177 Query: 687 VCPEFQNLTGDVISRTAFG----------SNFQEGMKIFQLQGELSERLIQAFQTLFIPG 836 + + T DVI TA G S++ +K + L +R+ F + Sbjct: 178 LGHDVHLFTLDVICETAMGVSTNAQTNADSDYVRAVKT--ISTVLHKRMFNIFYRFDLT- 234 Query: 837 YWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQ------ 998 Y P R RA++ + + I+ ++E ++ S M Sbjct: 235 YMLTPLAWAER-RALNVLHKFTEKIIVQRREELLRGGVTQTTDGADVGAKSKMVFLDILL 293 Query: 999 QSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG 1178 QSN + L+ DI +E F F G +TTS +T+ ++++PE Q K EE++ G Sbjct: 294 QSNID-DKPLTNLDIREEVDTFMFEGHDTTSSGITFFFYNIALYPECQRKCVEEIVSVLG 352 Query: 1179 RTTPD---FESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPI 1349 + T ++ L+ L + + E LR+YP + L R+ + E+ G PAG N+ + Sbjct: 353 KDTETPVTYDLLNNLNYMDLCIKETLRMYPSVPLLGRKVLQECEINGKIIPAGTNIGISP 412 Query: 1350 LFIHHDPDIWGKDAREFNPERFADGISNAAK-RPAAFFPFGGGPRICIGQNFALQEAKMA 1526 LF+ DI + F PERF D +++A K P A+ PF GPR CIGQ FA+ E K Sbjct: 413 LFLGRSEDI-SSEPNTFKPERF-DVVTSAEKLNPHAYIPFSAGPRNCIGQKFAMLEIKAI 470 Query: 1527 LSTILQRFSFELSPSYIHAPYTV--ITLQPQHGAQIRLKK 1640 + +L+ + E + +P + + L+ + +LKK Sbjct: 471 AANVLRHYEIEFVGNAEESPVLIAELILRTKDPLMFKLKK 510
>Q98T91:C340_ORYLA Cytochrome P450 3A40 - Oryzias latipes (Medaka fish) (Japanese| ricefish) Length = 502 Score = 128 bits (321), Expect = 9e-29 Identities = 106/417 (25%), Positives = 181/417 (43%), Gaps = 18/417 (4%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANHEGEK 542 K++GK + G P + + DP ++ +L + + F +R+ R+ L + ++ E ++ Sbjct: 66 KKYGKTWGIYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNFRLNGPLYDAVSIAEDDQ 125 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + R +L+P+F ++K M + +I + + E+ F + DV Sbjct: 126 WKRIRSVLSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKDEPLEMK--EYFGPYSMDV 183 Query: 723 ISRTAFG--------------SNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWF--FPT 854 ++ TAF +N ++ +K L F + + F FP+ Sbjct: 184 VTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLAVAFFPFLGPILEKFEFSLFPS 243 Query: 855 KNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSI 1034 A R+I K N S NG + GLS Sbjct: 244 SVMDFFFAALRKI----------KANHENNKQKSRIDFLQLMIDSQKNNQNGLQDKGLSD 293 Query: 1035 EDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSR 1211 +I+ + +F FAG ETTS LT+ L+ +PE +K ++E+ F P + L Sbjct: 294 HEILSQAMIFIFAGYETTSSSLTFLAYNLATNPEVMKKLQKEIDATFPNKAPVQYVPLME 353 Query: 1212 LKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDA 1391 ++ + + E LRLYP L R +E+ G+ P + +M+P +H DP++W + Sbjct: 354 MEYLDCVVNESLRLYPIAARLERVAKATVEVNGLVIPKDMVVMVPTWPLHRDPELW-PEP 412 Query: 1392 REFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 +F PERF+ + P + PFG GPR CIG FAL K+A+ ILQ + F + Sbjct: 413 EKFKPERFSKENKDTFD-PYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSV 468
>Q964R1:CP6J1_BLAGE Cytochrome P450 6j1 - Blattella germanica (German cockroach)| Length = 501 Score = 127 bits (319), Expect = 2e-28 Identities = 116/402 (28%), Positives = 180/402 (44%), Gaps = 15/402 (3%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQR---STRIGRLLANGLANHEGEKWAKHRRILNPAF 578 P ++V D E+V+ IL +F + + L AN + G+KW R L P F Sbjct: 85 PALLVNDLEIVKNILVKDSRNFIDRMVKVDESLSPLNANAIFALRGQKWKHVRTSLTPTF 144 Query: 579 HHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQE 758 K+K M + C ++++ E A+ V V + T DV + AFG E Sbjct: 145 TTGKMKNMFYLVDKCGQQLVLFIEKFAKAEN--PVAVKDAVERFTMDVTAMCAFGI---E 199 Query: 759 GMKIFQLQGELSERLIQAFQTLFIPGY-----WFFP-TKNNRRMRAIDREIRMILRGIIG 920 + + E S L + FQ F +F P +N R++ +D EI +R I+ Sbjct: 200 CNSLQDPKAEFSNLLHRIFQLSFTSAVANLATFFAPWVQNFFRLKLMDSEIEDRIRDIVW 259 Query: 921 KKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLL 1100 + + +++ L +D + + F AG T+S+ L Sbjct: 260 RAVHLREKTGEKRNDLLDYLMELRTSETSK-----LDGDDFVAQAFGFLVAGFHTSSMTL 314 Query: 1101 TWTLIVLSMHPEWQEKAREEVL----HYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPIT 1268 T+ L LS+H + Q AR E+ H+ + T + S+ +K + M+ E LR YP I Sbjct: 315 TFALYELSVHQDIQTTARTEIKDVLEHHKKKVT--YYSIKDMKYLDMVVNETLRKYPAIP 372 Query: 1269 FLTRRTYKAMELG-GIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKR 1445 FL RR + L + PAG + +P+ +HHD + A+ F+PERF++ N Sbjct: 373 FLDRRCQEDYPLTQDLMLPAGTGVYIPVYALHHDSKYFPSPAK-FDPERFSE--KNKQNI 429 Query: 1446 PA-AFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSP 1568 P A+ PFG GPR CIG F + K AL IL +FE+SP Sbjct: 430 PHFAYMPFGEGPRNCIGMRFGSMQVKAALIHILS--NFEVSP 469
>Q9VGB5:CP135_DROME Probable cytochrome P450 313a5 - Drosophila melanogaster (Fruit fly)| Length = 487 Score = 127 bits (319), Expect = 2e-28 Identities = 108/444 (24%), Positives = 198/444 (44%), Gaps = 29/444 (6%) Frame = +3 Query: 336 RVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREIL-----SNKFGHFGKQRSTRIG 500 R + + T K +GK TW G TP ++ +P+++ +I SN+ K S+ +G Sbjct: 52 RKIRLRTILFKIYGKTVLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLG 111 Query: 501 RLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCE 680 GL + W + R++L P+F + + +PV + ++T + + Sbjct: 112 L----GLLTLKNNHWNERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGG---D 164 Query: 681 VDVCPEFQNLTGDVISRTAFG------SNFQEGMKIFQLQGELSERLIQAFQTL--FIPG 836 +++ PE + + ++ G +N+Q G L+++++ L IP Sbjct: 165 INLLPELNKWSFKIAAQITMGDEVRNQANYQNG------------NLLESYKALNNLIPI 212 Query: 837 YWFFPTKNN-----------RRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXX 983 P N RR+ A + ++ II KK + N Sbjct: 213 GVVMPWLRNKYLGKLFSYEKRRLEAATQS-NAFIKDIIDKKLSSTDNSSEPAL------- 264 Query: 984 XSNMQQSNGKANLG-LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREE 1160 + + +G LS +D++ E FA +T S+ + LI+++M P++Q+ EE Sbjct: 265 ---IDRILNLVRIGELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEE 321 Query: 1161 VLHYF---GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELG-GIKYPAG 1328 + F G L +L + + +E +RL P + L R+T +++L G P G Sbjct: 322 LAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEG 381 Query: 1329 VNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFAL 1508 V LM+ I H + DIWG A FNP+ F + A+ P ++ PF G + C+G +L Sbjct: 382 VTLMIDIFHTHRNKDIWGPQANAFNPDNFLPE-NKRARPPYSYLPFSKGKKTCLGWKLSL 440 Query: 1509 QEAKMALSTILQRFSFELSPSYIH 1580 AK+AL+ IL+ ++ LS ++++ Sbjct: 441 ISAKLALAKILR--NYMLSTTFLY 462
>Q9VHP4:CP313_DROME Probable cytochrome P450 313b1 - Drosophila melanogaster (Fruit fly)| Length = 502 Score = 126 bits (317), Expect = 3e-28 Identities = 108/441 (24%), Positives = 195/441 (44%), Gaps = 29/441 (6%) Frame = +3 Query: 315 GSHHIAPRVLPMFTNAIKEHGKVSF-TWFGPTPRVMVPDPELVREILSNKF----GHFGK 479 G + P + + + K F +W G + + + DP V +IL++ G F + Sbjct: 44 GLQMMNPETFLQYMDGLSRQFKAPFISWMGTSCFLYINDPHSVEQILNSTHCTNKGDFYR 103 Query: 480 QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSM 659 S+ IG +GL +W KHRR++NPAF + + LP+F+A E ++ + E Sbjct: 104 FMSSAIG----DGLFTSSSPRWHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEG 159 Query: 660 SAQGLCEVDVCPEFQNLTGDVISRTAFGS--NFQE--GMKIFQLQGELSERLIQAFQTLF 827 G +++ + + + +T G NFQ + IF+ L+E ++ + Sbjct: 160 VQHGK-RLEIYQILKKIVLEAACQTTMGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLS-- 216 Query: 828 IPGYWFFPTKNNRR--MRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQ 1001 W +P RR + + +++ IL G I E+ ++ + + Sbjct: 217 ---PWLYPDLIYRRSGLFRLQQKVVGILFGFI---EQLLEPIVSVVAANSNPDQQRSEME 270 Query: 1002 SNGKANL-------------GLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQ 1142 GK+ LS +D+ E + A ETTS L +T++ L+MHP +Q Sbjct: 271 MRGKSKAIFIEQVREHVERGQLSWQDVRDEANVTIAATFETTSTALYFTILCLAMHPCYQ 330 Query: 1143 EKAREEVLHYFGRTTP-DFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMEL----G 1307 EK +E++ + + E L RL+ M+ E +RL+ P+ + R + ++L G Sbjct: 331 EKLHKELVTELPPSGDINLEQLQRLEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDG 390 Query: 1308 GIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRIC 1487 P G + + I + D +WG +R +NP+ G+ + + AF PF G R+C Sbjct: 391 EFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNPDAHF-GLDSPQRHAFAFVPFTKGLRMC 449 Query: 1488 IGQNFALQEAKMALSTILQRF 1550 IG +A K+ L+ I + + Sbjct: 450 IGYRYAQMLMKLLLARIFRSY 470
>O42563:CP3AR_ONCMY Cytochrome P450 3A27 - Oncorhynchus mykiss (Rainbow trout) (Salmo| gairdneri) Length = 518 Score = 126 bits (316), Expect = 4e-28 Identities = 103/431 (23%), Positives = 186/431 (43%), Gaps = 28/431 (6%) Frame = +3 Query: 354 TNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNK-FGHFGKQRSTRIGRLLANGLANH 530 T +++G++ + G P + + D +++ +L + + F +R+ + L + L+ Sbjct: 63 TECFQKYGRIWGIYDGRQPVLCIMDKSMIKTVLIKECYNIFTNRRNFHLNGELFDALSVA 122 Query: 531 EGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNL 710 E + W + R +L+P+F ++K M + +++ + EV F Sbjct: 123 EDDTWRRIRSVLSPSFTSGRLKEMFGIMKQHSSTLLSGMKKQADKDQTIEVKEF--FGPY 180 Query: 711 TGDVISRTAFG--------------SNFQEGMK------------IFQLQGELSERLIQA 812 + DV++ TAF SN ++ +K +F G + E++ Sbjct: 181 SMDVVTSTAFSVDIDSLNNPSDPFVSNVKKMLKFDLFNPLFLLVALFPFTGPILEKM--- 237 Query: 813 FQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSN 992 + FFPT A+ L I ++ + Sbjct: 238 -------KFSFFPT-------AVTDFFYASLAKIKSGRDTGNSTNRVDFLQLMIDSQKGS 283 Query: 993 MQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHY 1172 ++ + GL+ +I+ + +F FAG ET+S +++ L+ + K +EE+ Sbjct: 284 DTKTGEEQTKGLTDHEILSQAMIFIFAGYETSSSTMSFLAYNLATNHHVMTKLQEEIDTV 343 Query: 1173 FGRTTP-DFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPI 1349 F P +E+L ++ + + E LRLYP L R K +E+ GI P +++P Sbjct: 344 FPNKAPIQYEALMQMDYLDCVLNESLRLYPIAPRLERVAKKTVEINGIVIPKDCIVLVPT 403 Query: 1350 LFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMAL 1529 +H DP+IW D EF PERF+ + + P + PFG GPR CIG FAL K+A+ Sbjct: 404 WTLHRDPEIW-SDPEEFKPERFSKE-NKESIDPYTYMPFGAGPRNCIGMRFALIMIKLAM 461 Query: 1530 STILQRFSFEL 1562 ILQ F+F + Sbjct: 462 VEILQSFTFSV 472
>Q9V769:C6A22_DROME Cytochrome P450 6a22 - Drosophila melanogaster (Fruit fly)| Length = 499 Score = 126 bits (316), Expect = 4e-28 Identities = 120/430 (27%), Positives = 193/430 (44%), Gaps = 18/430 (4%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHF---GKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAF 578 P V+V D EL ++IL F +F G + R L + L +G KW R+ ++P F Sbjct: 79 PVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGH-LFRIDGPKWRPLRQKMSPTF 137 Query: 579 HHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEV-DVCPEFQNLTGDVISRTAFG---S 746 K+K M P EE+ T+ ++ +C + ++ T DVI R AFG + Sbjct: 138 TSAKMKYMFPTVCEVGEEL-TQVCGELADNAMCGILEIGDLMARYTSDVIGRCAFGVECN 196 Query: 747 NFQEGMKIFQLQGE--LSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIG 920 + F + G SER FI F RMR I ++I GI+ Sbjct: 197 GLRNPEAEFAIMGRRAFSERRHCKLVDGFIES--FPEVARFLRMRQIHQDITDFYVGIV- 253 Query: 921 KKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLL 1100 +E + M+Q L+IE++ + +F+ AG +T++ L Sbjct: 254 -RETVKQREEQGIVRSDFMNLLIEMKQRGE-----LTIEEMAAQAFIFFAAGFDTSASTL 307 Query: 1101 TWTLIVLSMHPEWQEKAREEVLHYFGRTTPDF--ESLSRLKIVTMIFYEVLRLYP---PI 1265 + L L+ P Q K REE+ +F +S+ L+ + ++ E LR YP + Sbjct: 308 GFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQL 367 Query: 1266 TFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKR 1445 T ++R Y A G L++P+ IHHDP ++ + +F PERF A+R Sbjct: 368 TRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALY-PEPHKFIPERFL--ADQLAQR 424 Query: 1446 P-AAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSP---SYIHAPYTVITLQPQ 1613 P AA+ PFG GPR CIG F + + L ++L+ F F + P I + I L P Sbjct: 425 PTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPA 484 Query: 1614 HGAQIRLKKI 1643 +G ++++++ Sbjct: 485 NGIYLKVQQL 494
>Q9VL92:CP4E3_DROME Cytochrome P450 4e3 - Drosophila melanogaster (Fruit fly)| Length = 526 Score = 125 bits (315), Expect = 5e-28 Identities = 112/436 (25%), Positives = 200/436 (45%), Gaps = 25/436 (5%) Frame = +3 Query: 339 VLPMFTNAIKEHGKVSFT-WFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRL--- 506 +L F + ++GK +F W G + +++ +P+ + IL+++ Q+ST L Sbjct: 55 ILSTFFDWWYDYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLI---QKSTIYDLLHPW 111 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 L +GL G KW KHR+++ P+FH ++ V + + +T+ + + + + +D Sbjct: 112 LGHGLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTI--ID 169 Query: 687 VCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLF--IPGYWFFPTKN 860 LT DVI TA G + ++QAF+ + I F P K Sbjct: 170 FQEHANYLTLDVICDTAMGVPINA-------MEQRDSSIVQAFRDMCYNINMRAFHPFKR 222 Query: 861 NRRMRAIDREIRMILR----------GIIGKKERAIKNXXXXXXXXXXXXXXS----NMQ 998 + R+ ++ E + II K+ A++N + Sbjct: 223 SNRVFSLTPEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTL 282 Query: 999 QSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG 1178 S+ L+ ++I +E F F G +TT+ +++++ +LS HP+ Q K E G Sbjct: 283 LSSTIDGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMG 342 Query: 1179 RT---TPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPI 1349 + F+ ++++K + + E R+YP + F+ R K ++ G P G L L + Sbjct: 343 HDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLAL 402 Query: 1350 LFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAF--FPFGGGPRICIGQNFALQEAKM 1523 + + ++ I+ KD F PERF + ++PA F PF GPR CIGQ FAL E K Sbjct: 403 ILLGYNDRIF-KDPHHFRPERFEE------EKPAPFEYLPFSAGPRNCIGQKFALLELKT 455 Query: 1524 ALSTILQRFSFELSPS 1571 +S +++ SFE+ P+ Sbjct: 456 VISKVVR--SFEVLPA 469
>P79152:CP3AJ_CAPAE Cytochrome P450 3A19 - Capra aegagrus (Wild goat)| Length = 218 Score = 125 bits (314), Expect = 6e-28 Identities = 65/178 (36%), Positives = 105/178 (58%), Gaps = 5/178 (2%) Frame = +3 Query: 1038 DIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRL 1214 +++ + +F F G ETTS L++ + L+ HP+ Q+K +EE+ F + P +++L ++ Sbjct: 5 ELVAQTTIFIFGGYETTSTSLSFIIYELATHPDVQQKLQEEIDATFPNKAPPTYDALVQM 64 Query: 1215 KIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAR 1394 + + M+ E LR++P L R K +E+ G+ P G +M+P+ +H++P+ W + Sbjct: 65 EYLDMVVNETLRMFPIAGRLERLCKKDVEIHGVSIPKGTTVMVPLFVLHNNPEFW-PEPE 123 Query: 1395 EFNPERFA----DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 EF PERF+ DGI+ P + PFG GPR C+G FAL K+AL ILQ FSF Sbjct: 124 EFRPERFSKKNKDGIN-----PYVYLPFGTGPRNCVGMRFALMNIKLALVRILQNFSF 176
>Q9V6H1:CP9H1_DROME Probable cytochrome P450 9h1 - Drosophila melanogaster (Fruit fly)| Length = 518 Score = 125 bits (313), Expect = 8e-28 Identities = 114/410 (27%), Positives = 184/410 (44%), Gaps = 26/410 (6%) Frame = +3 Query: 420 VPDPELVREILSNKFGHFGKQRSTRIG---RLLANGLANHEGEKWAKHRRILNPAFHHEK 590 V DPEL++ I +F HF S +L+ L + +W + R IL PAF K Sbjct: 86 VRDPELIKLIGIKEFDHFVNHNSMHNNIQESILSKSLISLRDGRWKEMRNILTPAFTGSK 145 Query: 591 IKRMLPVFSACCEEMITRWENSM--SAQGLCEVDVCPEFQNLTGDVISRTAFG---SNFQ 755 ++ M + +C EE + + + S E+++ F DVI+ AFG ++F+ Sbjct: 146 MRIMYDLIQSCSEEGVIHIQEQLELSQDASIELEMKDYFTRFANDVIATVAFGISINSFR 205 Query: 756 EGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNN-RRMRAIDREIRMILRGIIGKKER 932 F G+ R I A+ + Y FP R++ +D + ++ R Sbjct: 206 RKDNEFFRIGQAMSR-ISAWSVVKAMLYALFPRLMKVLRIQVLDTKNIDYFSSLVTAAMR 264 Query: 933 AIKNXXXXXXXXXXXXXXSNMQQ-----SNGKANLGLS---IEDIIQECKLFYFAGMETT 1088 + + Q+ K L S +D++ +C LF+FAG E Sbjct: 265 YRQEHKVVRPDMIHLLMEAKQQRLADLSDKSKDELYYSEFTADDLLAQCLLFFFAGFEII 324 Query: 1089 SVLLTWTLIVLSMHPEWQEKAREEVL--HYFGRTTP-DFESLSRLKIVTMIFYEVLRLYP 1259 S L + L ++P Q++ EE++ H + P ++ L+++K + M+ E LR +P Sbjct: 325 SSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQPLTYDKLTKMKYLDMVVLEALRKWP 384 Query: 1260 PITFLTRRTYKAMEL----GGIKYPA--GVNLMLPILFIHHDPDIWGKDAREFNPERFAD 1421 P R + ++L G + A G L +PI +HHDP+ + +D FNPERFAD Sbjct: 385 PSISTDRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHHDPENF-EDPEFFNPERFAD 443 Query: 1422 GISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPS 1571 G A + PFG GPR CIG AL E K + +L +F+L P+ Sbjct: 444 G---HALESRVYMPFGVGPRNCIGNRMALMELKSIVYQLL--LNFKLLPA 488
>Q9Y6A2:CP46A_HUMAN Cytochrome P450 46A1 - Homo sapiens (Human)| Length = 500 Score = 124 bits (312), Expect = 1e-27 Identities = 122/446 (27%), Positives = 195/446 (43%), Gaps = 18/446 (4%) Frame = +3 Query: 327 IAPRVLP-MFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILS----NKFGHFGKQRST 491 + RVL +F + K++G V V+V PE V++ L NK + T Sbjct: 55 VGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQT 114 Query: 492 RIG-RLLANGLANH-EGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSA 665 G RL GL + E+W K RR+++ AF + ++ F+ E+++ E A Sbjct: 115 VFGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILE--AKA 172 Query: 666 QGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELS-------ERLIQAFQTL 824 G V + D++++ AFG E + Q LS E + + TL Sbjct: 173 DGQTPVSMQDMLTYTAMDILAKAAFG---METSMLLGAQKPLSQAVKLMLEGITASRNTL 229 Query: 825 --FIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQ 998 F+PG K R +R R +R + R + ++ A+K +++ Sbjct: 230 AKFLPG----KRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVP---------ADIL 276 Query: 999 QSNGKANLGLSIED-IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF 1175 KA G ++ ++ F+ AG ET++ L +T++ LS PE + + EV Sbjct: 277 TQILKAEEGAQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVI 336 Query: 1176 G-RTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPIL 1352 G + DFE L RL+ ++ + E LRLYPP R + + G++ P L+ Sbjct: 337 GSKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFST- 395 Query: 1353 FIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALS 1532 ++ D + +D FNP+RF G A K +FPF G R CIGQ FA E K+ ++ Sbjct: 396 YVMGRMDTYFEDPLTFNPDRFGPG---APKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMA 452 Query: 1533 TILQRFSFELSPSYIHAPYTVITLQP 1610 +LQR F L P TL+P Sbjct: 453 KLLQRLEFRLVPGQRFGLQEQATLKP 478
>Q9VS79:CP4D8_DROME Cytochrome P450 4d8 - Drosophila melanogaster (Fruit fly)| Length = 463 Score = 124 bits (311), Expect = 1e-27 Identities = 120/456 (26%), Positives = 199/456 (43%), Gaps = 30/456 (6%) Frame = +3 Query: 363 IKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRI-GRLLANGLANHEGE 539 + + G + W +M D EL ++LS++ H K ++ G+ L NGL +G+ Sbjct: 20 VLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQ-EHLVKHPVYKVLGQWLGNGLLLSDGK 78 Query: 540 KWAKHRRILNPAFHHEKIKRMLPVF---SACCEEMITRWENSMSAQGLCEVDVCPEFQNL 710 W + R+I+ P FH +++ + VF S C + + + N + DV Sbjct: 79 VWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNT------FDVYRSICAA 132 Query: 711 TGDVISRTAFGSNF----QEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNR---R 869 D+I+ TA G+ E + E + L F ++++ F + R Sbjct: 133 ALDIIAETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWR 192 Query: 870 MRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSN----------MQQSNGKAN 1019 + R ++ +I K+ +A+++ S M +G+ Sbjct: 193 QTQLIRTMQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDGRP- 251 Query: 1020 LGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG--RTTP- 1190 L+ ++I +E F F G +TT+ L++ L LS HPE Q K EE++ G R+ P Sbjct: 252 --LTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPV 309 Query: 1191 DFESLSRLKIVTMIFYEVLRLYPPITFLTRR-----TYKAMELGGIKYPAGVNLMLPILF 1355 L LK + + E LR+YPP+ + R+ Y G PAG +++ I Sbjct: 310 SIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFG 369 Query: 1356 IHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALST 1535 +H P+ + + EF PER +G A P PF GPR CIGQ FA E KM L+ Sbjct: 370 VHRQPETF-PNPDEFIPERHENGSRVA---PFKMIPFSAGPRNCIGQKFAQLEMKMMLAK 425 Query: 1536 ILQRFSFELSPSYIHAPYTV-ITLQPQHGAQIRLKK 1640 I++ +EL P V I L+ + G Q+ ++K Sbjct: 426 IVR--EYELLPMGQRVECIVNIVLRSETGFQLGMRK 459
>Q9VB31:C6A18_DROME Probable cytochrome P450 6a18 - Drosophila melanogaster (Fruit fly)| Length = 507 Score = 123 bits (309), Expect = 2e-27 Identities = 117/439 (26%), Positives = 198/439 (45%), Gaps = 27/439 (6%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHF---GKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAF 578 P V D EL ++IL F +F G + + + A+ L N +G +W R L+ F Sbjct: 82 PAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAH-LFNLDGPQWRLLRSKLSSTF 140 Query: 579 HHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEV-DVCPEFQNLTGDVISRTAFGSNFQ 755 K+K M P + EE + +S + +V D+ F T DVI AFG Sbjct: 141 TSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARF---TVDVIGTCAFG---- 193 Query: 756 EGMKIFQLQGELSE-------RLIQAFQTLFIPGYWFFPTKNNRRM------RAIDREIR 896 +K L+ E +E L+ + + G RR+ I + Sbjct: 194 --IKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQ 251 Query: 897 MILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAG 1076 I++ + +E+ NM NG+ GL++++I+ + +F+ AG Sbjct: 252 RIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAG 311 Query: 1077 METTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDF--ESLSRLKIVTMIFYEVLR 1250 +T+S + + L L+ +P Q+K R E+ + F E + LK + + E LR Sbjct: 312 FDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLR 371 Query: 1251 LYPPITFLTRRTYKAMELGG---IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFAD 1421 Y + + R K + G AG ++++P IHHDP I+ + EF PERF+ Sbjct: 372 HYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIY-PEPNEFRPERFSP 430 Query: 1422 GISNAAKRPA-AFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF---ELSPSYI-HAP 1586 +AKRP+ A+ PFG GPR CIG F +A++ L+ +++ F+F +P + P Sbjct: 431 --EESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDP 488 Query: 1587 YTVITLQPQHGAQIRLKKI 1643 ++ I L + G Q++++ I Sbjct: 489 HSAILLGIKGGIQLKVEAI 507
>Q9V4T5:CP4E1_DROME Probable cytochrome P450 4e1 - Drosophila melanogaster (Fruit fly)| Length = 531 Score = 123 bits (308), Expect = 3e-27 Identities = 118/427 (27%), Positives = 179/427 (41%), Gaps = 23/427 (5%) Frame = +3 Query: 339 VLPMFTNAIKEHGKVSFT-WFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN 515 +L F E+GK +F W G +MV +P+ + ILS++ L Sbjct: 55 ILNRFFGWWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGL 114 Query: 516 GLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMS--AQGLCEVDV 689 GL G KW KHR+++ PAFH +L F E T++ + + A G D Sbjct: 115 GLLTSTGSKWHKHRKMITPAFHFN----ILQDFHEVMNENSTKFIDQLKKVADGGNIFDF 170 Query: 690 CPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQ--TLFIPGYWFFPTKNN 863 E LT DVI TA G + S ++QAF+ T I F P K N Sbjct: 171 QEEAHYLTLDVICDTAMGVSINA-------MENRSSSVVQAFKDITYTIKMRAFSPWKRN 223 Query: 864 RRMRAIDRE----------IRMILRGIIGKKERAIKNXXXXXXXXXXXXXXS----NMQQ 1001 + + E ++ II K+ K+ + Sbjct: 224 KYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLL 283 Query: 1002 SNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR 1181 S+ L+ +++ +E F F G +TT+ + + + +LS HP+ QEK E G Sbjct: 284 SSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGA 343 Query: 1182 T----TPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPI 1349 + F+ +S +K + + E RLYP + F+ R T K + G P G L L + Sbjct: 344 SGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGL 403 Query: 1350 LFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMAL 1529 L + ++ ++ KD +F PERF P + PF GPR CIGQ FAL E K + Sbjct: 404 LMLGYNDRVF-KDPHKFQPERF----DREKPGPFEYVPFSAGPRNCIGQKFALLEIKTVV 458 Query: 1530 STILQRF 1550 S I++ F Sbjct: 459 SKIIRNF 465
>P33270:CP6A2_DROME Cytochrome P450 6a2 - Drosophila melanogaster (Fruit fly)| Length = 506 Score = 122 bits (307), Expect = 4e-27 Identities = 104/406 (25%), Positives = 178/406 (43%), Gaps = 20/406 (4%) Frame = +3 Query: 393 WFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGR--LLANGLANHEGEKWAKHRRIL 566 +F P + D +L + IL F +F + GR L L N +G+KW R+ L Sbjct: 74 YFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLDGKKWKDMRQRL 133 Query: 567 NPAFHHEKIKRMLPVFSACCEEMI-TRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG 743 P F K+K M P EE + E +AQ +++ T DVI AFG Sbjct: 134 TPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFG 193 Query: 744 ---SNFQEGMKIFQLQGE--LSERLIQAFQTLFIPGYWFFPTKNNR-RMRAIDREIRM-- 899 + + + F+ G+ ++ T+F+ + FP +R RMR + ++ Sbjct: 194 IECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFV---FSFPKLASRLRMRMMPEDVHQFF 250 Query: 900 --ILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFA 1073 ++ I +ER + NG+ G+ I ++ + +FY A Sbjct: 251 MRLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVA 310 Query: 1074 GMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF----GRTTPDFESLSRLKIVTMIFYE 1241 G ET+S +++ L L+ + + Q++ R E+ G+ T +ES+ + + + E Sbjct: 311 GFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLT--YESIKAMTYLNQVISE 368 Query: 1242 VLRLYPPITFLTRRTYKAMELGG---IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 LRLY + L R+ + G + G +++P H D D++ + F+PER Sbjct: 369 TLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLY-PNPETFDPER 427 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 F+ AA+ + PFG GPR CIG F +A++ L+ I+ RF Sbjct: 428 FSPE-KVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRF 472
>O08336:CYPE_BACSU Probable bifunctional P-450:NADPH-P450 reductase 2 [Includes:| Cytochrome P450 102 - Bacillus subtilis Length = 1054 Score = 122 bits (306), Expect = 5e-27 Identities = 103/364 (28%), Positives = 156/364 (42%), Gaps = 8/364 (2%) Frame = +3 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W K RIL P+F + +K + ++I +W + E+DV + LT D Sbjct: 98 WQKAHRILLPSFSQKAMKGYHSMMLDIATQLIQKWSRLNPNE---EIDVADDMTRLTLDT 154 Query: 723 ISRTAFGSNFQEGMK------IFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAID 884 I F F + I + L E + Q+ + L + TK + + I+ Sbjct: 155 IGLCGFNYRFNSFYRDSQHPFITSMLRALKEAMNQS-KRLGLQDKMMVKTKLQFQ-KDIE 212 Query: 885 REIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLF 1064 ++ R I +K +N + + L E+I + F Sbjct: 213 VMNSLVDRMIAERKANPDENIKDLLSLM--------LYAKDPVTGETLDDENIRYQIITF 264 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIFYEV 1244 AG ETTS LL++ + L HPE +KA+EE TP+++ + +LK + M+ E Sbjct: 265 LIAGHETTSGLLSFAIYCLLTHPEKLKKAQEEADRVLTDDTPEYKQIQQLKYIRMVLNET 324 Query: 1245 LRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILF--IHHDPDIWGKDAREFNPERFA 1418 LRLYP + + LGG +YP + +L +H D + WG DA +F PERF Sbjct: 325 LRLYPTAPAFSLYAKEDTVLGG-EYPISKGQPVTVLIPKLHRDQNAWGPDAEDFRPERFE 383 Query: 1419 DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVI 1598 D S A+ PFG G R CIG FALQEA M L +L+ F Y + Sbjct: 384 DPSSIPHH---AYKPFGNGQRACIGMQFALQEATMVLGLVLKHFELINHTGYELKIKEAL 440 Query: 1599 TLQP 1610 T++P Sbjct: 441 TIKP 444
>Q27593:CP6A8_DROME Cytochrome P450 6a8 - Drosophila melanogaster (Fruit fly)| Length = 506 Score = 122 bits (306), Expect = 5e-27 Identities = 109/407 (26%), Positives = 183/407 (44%), Gaps = 19/407 (4%) Frame = +3 Query: 393 WFGPTPRVMVPDPELVREILSNKFGHFGKQRS--TRIGRLLANGLANHEGEKWAKHRRIL 566 +F +P V D EL ++IL F +F + ++ L N +G +W R L Sbjct: 77 FFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKL 136 Query: 567 NPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEV-DVCPEFQNLTGDVISRTAFG 743 + F K+K M P + E +T + + E+ D+ F T DVI AFG Sbjct: 137 SSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARF---TVDVIGTCAFG 193 Query: 744 ---SNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAI-------DREI 893 ++ ++ F G+ S L+ + G+ K R++ + + Sbjct: 194 IQCNSLRDEKAEFLYFGKRS--LVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYS 251 Query: 894 RMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFA 1073 R++ + +++ IK M NG GL++E+++ + +F+ A Sbjct: 252 RIVTETVAVREKEHIKRNDFMDMLIELKNQ-KEMTLENGDVVRGLTMEEVLAQAFVFFIA 310 Query: 1074 GMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDF--ESLSRLKIVTMIFYEVL 1247 G ET+S + + L L+ +P+ Q+K R EV + +F E LK + + E L Sbjct: 311 GFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETL 370 Query: 1248 RLYPPITFLTRRTYKAMELGG---IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFA 1418 RLY + L R K + G AG ++++P IHHDP I+ + EF PERF+ Sbjct: 371 RLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIY-PEPFEFRPERFS 429 Query: 1419 DGISNAAKRPA-AFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 +A RP+ A+ PFG GPR CIG F +A++ L+ +++ F F Sbjct: 430 P--EESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKF 474
>Q9V773:C6A20_DROME Probable cytochrome P450 6a20 - Drosophila melanogaster (Fruit fly)| Length = 501 Score = 122 bits (306), Expect = 5e-27 Identities = 111/407 (27%), Positives = 179/407 (43%), Gaps = 16/407 (3%) Frame = +3 Query: 414 VMVPDPELVREILSNKFGHF---GKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHH 584 V+V D + + +L +F F G + R L AN L N +G+KW R+ L P F Sbjct: 82 VVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSAN-LVNIDGQKWKTLRQKLTPTFTS 140 Query: 585 EKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG----SNF 752 K+K M P +E+I + + SA +++ T DVI AFG S Sbjct: 141 GKMKTMFPTILTVGDELIRVFGETASADS-DSMEITNVVARFTADVIGSCAFGLDCHSLS 199 Query: 753 QEGMKIFQL-QGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGII-GKK 926 K Q+ ++ER L + G K RM+A +E+ II Sbjct: 200 DPKAKFVQMGTTAITERRHGKSMDLLLFGAPELAAK--LRMKATVQEVEDFYMNIIRDTV 257 Query: 927 ERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTW 1106 + +KN ++ NG GL+ +I + +F+ AG ET+S + + Sbjct: 258 DYRVKN-NVKRHDFVDMLIEMKLKFDNGDKENGLTFNEIAAQAFIFFLAGFETSSTTMGF 316 Query: 1107 TLIVLSMHPEWQEKAREEV----LHYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFL 1274 L L+ H + Q+K R E+ + G+ D++S+ + + + E +R P + L Sbjct: 317 ALYELACHQDIQDKLRTEINTVLKQHNGKL--DYDSMREMTYLEKVIDETMRKRPVVGHL 374 Query: 1275 TRRTYKAMELGGIKY--PAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRP 1448 R + + KY G +++P L IHHDP+ + + +F PERF + +RP Sbjct: 375 IRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFY-PEPEKFIPERFDE--DQVQQRP 431 Query: 1449 A-AFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAP 1586 A F PFG GPR CIG F + + ++ ++ F FE P+ P Sbjct: 432 ACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTKTVVP 478
>Q9VG82:CP9F2_DROME Probable cytochrome P450 9f2 - Drosophila melanogaster (Fruit fly)| Length = 516 Score = 121 bits (304), Expect = 9e-27 Identities = 113/443 (25%), Positives = 201/443 (45%), Gaps = 34/443 (7%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQRST----------RIGRLLANGLANHEGEKWAKHR 557 P +MV DP+L+++I F HF R+ + L + L + +W R Sbjct: 79 PLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDARWKDMR 138 Query: 558 RILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTA 737 L+PAF K+++M + + +E + + S E+D+ T DVI+ TA Sbjct: 139 STLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVIASTA 198 Query: 738 FG---SNFQEGMKIFQLQGE--LSERLIQAFQTLFIPGYWFFPTKNNRRMRAI---DRE- 890 FG ++F++ F G+ + +Q+ + + FF K ++ + DR+ Sbjct: 199 FGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFML-----FFALKGLNKILKVELFDRKS 253 Query: 891 ----IRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECK 1058 +R++L + ++E I +++ A S DI+ +C Sbjct: 254 TQYFVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQT-EKTKASAVREWSDRDIVAQCF 312 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHY---FGRTTPDFESLSRLKIVTM 1229 +F+FAG ET++VL+ +T L + + Q++ EEV +E++ +K + Sbjct: 313 VFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYLDQ 372 Query: 1230 IFYEVLRLYPPITFLTRRTYK--AMELGG--IKYPAGVNLMLPILFIHHDPDIWGKDARE 1397 + EVLR +P + R K ++ G ++ G + LP H DP + ++ + Sbjct: 373 VVNEVLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYF-ENPMK 431 Query: 1398 FNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYI 1577 F+PERF+D + + +P +FPFG G R CIG FAL EAK + +L+ + F + Sbjct: 432 FDPERFSDE-NKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSC 490 Query: 1578 HAPYTVIT----LQPQHGAQIRL 1634 P +IT L P+ G I+L Sbjct: 491 -IPLELITSGFQLSPKGGFWIKL 512
>Q9V4U7:C6A14_DROME Probable cytochrome P450 6a14 - Drosophila melanogaster (Fruit fly)| Length = 509 Score = 120 bits (300), Expect = 3e-26 Identities = 106/417 (25%), Positives = 190/417 (45%), Gaps = 24/417 (5%) Frame = +3 Query: 387 FTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGR--LLANGLANHEGEKWAKHRR 560 +T+F T ++ D + +++++ F +F + + R L L EGE+W R Sbjct: 73 YTFFKRT--ALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLFALEGEEWRAMRH 130 Query: 561 ILNPAFHHEKIKRM----LPVFSACCEEMITRWENSMSAQGLCEV-DVCPEFQNLTGDVI 725 L P F KIK+M + V + M + + +G E+ D+C F T DVI Sbjct: 131 KLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGNVEIKDLCARF---TTDVI 187 Query: 726 SRTAFG---SNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMR---AIDR 887 AFG ++ Q+ F+ +G E + + + + F + R++R D Sbjct: 188 GSCAFGLECNSLQDPSAEFRQKGR--EIFTRRRHSTLVQSFIFTNARLARKLRIKVLPDD 245 Query: 888 EIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGK------ANLGLSIEDIIQ 1049 + + + + +KN Q K + GL++E + Sbjct: 246 LTQFFMSTVKNTVDYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAA 305 Query: 1050 ECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP---DFESLSRLKI 1220 + +F+ AG ET+S ++ L L++ P+ Q++ REE+ +++ L+++ Sbjct: 306 QAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTY 365 Query: 1221 VTMIFYEVLRLYPPITFLTRRTYKAMEL--GGIKYPAGVNLMLPILFIHHDPDIWGKDAR 1394 + + E LR +P + L R T K ++ I G+ ++P+ IHHDP+I+ + Sbjct: 366 LDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIY-PEPE 424 Query: 1395 EFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELS 1565 +F+P RF D + P A+ PFG GPR CIG F +AK+ L ++L+RF F +S Sbjct: 425 KFDPSRF-DPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVS 480
>Q9WVK8:CP46A_MOUSE Cytochrome P450 46A1 - Mus musculus (Mouse)| Length = 500 Score = 119 bits (297), Expect = 6e-26 Identities = 113/438 (25%), Positives = 193/438 (44%), Gaps = 17/438 (3%) Frame = +3 Query: 348 MFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILS----NKFGHFGKQRSTRIG-RLLA 512 +F + K++G V V+V PE V++ L NK + T G RL Sbjct: 63 VFLDWAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFG 122 Query: 513 NGLANH-EGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDV 689 GL + + +W K R++++ AF + ++ F+ E+++ E A G V + Sbjct: 123 QGLVSECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILE--AKADGQTPVSM 180 Query: 690 CPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTL---------FIPGYW 842 T D++++ AFG E + Q LS+ + + + F+PG Sbjct: 181 QDMLTCATIDILAKAAFG---METSMLLGAQKPLSQAVKVMLEGISASRNTLAKFMPG-- 235 Query: 843 FFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANL 1022 K R +R R +R + + + ++ A+K +++ KA Sbjct: 236 --KRKQLREIRESIRLLRQVGKDWVQRRREALKRGEDMP---------ADILTQILKAEE 284 Query: 1023 GLSIEDIIQECKL-FYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG-RTTPDF 1196 G ++++ + + F+ AG ET++ L +T++ LS PE + + EV G + D+ Sbjct: 285 GAQDDEVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDY 344 Query: 1197 ESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDI 1376 E L RL+ ++ + E LRLYPP R + + G++ P L+ ++ D Sbjct: 345 EDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFST-YVMGRMDT 403 Query: 1377 WGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 + +D FNP+RF G A K +FPF G R CIGQ FA E K+ ++ +LQR F Sbjct: 404 YFEDPLTFNPDRFGPG---APKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEF 460 Query: 1557 ELSPSYIHAPYTVITLQP 1610 L P TL+P Sbjct: 461 RLVPGQRFGLQEQATLKP 478
>O46051:C4D14_DROME Probable cytochrome P450 4d14 - Drosophila melanogaster (Fruit fly)| Length = 507 Score = 118 bits (296), Expect = 7e-26 Identities = 110/432 (25%), Positives = 185/432 (42%), Gaps = 22/432 (5%) Frame = +3 Query: 339 VLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANG 518 + M I E GK T M D +++ I+S++ + + L +G Sbjct: 56 IFDMQFRLIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDG 115 Query: 519 LANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPE 698 L +G+KW + R+I+ PAFH + ++ + VF M+ + + A G +++ P Sbjct: 116 LLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYD--RADGKTVINMFPV 173 Query: 699 FQNLTGDVISRTAFG--------SNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPT 854 D+I+ TA G F + L+ER + Q L F+P Sbjct: 174 ACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPK 233 Query: 855 KNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLG--- 1025 ++ A+ + + +I ++ R + +++ Q A L Sbjct: 234 LLDKLNDAV-KNMHDFTNSVITER-RELLQKAIADGGDADAALLNDVGQKRRMALLDVLL 291 Query: 1026 --------LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG- 1178 LS +DI +E F F G +TT+ + +T +L+ HPE Q + +EV G Sbjct: 292 KSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGD 351 Query: 1179 -RTTP-DFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPIL 1352 ++ P + L LK + + E LRL+P + + R + L G PA N+++ I Sbjct: 352 DKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILIY 411 Query: 1353 FIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALS 1532 DPD + D +F P+RF+ P A+ PF GPR CIGQ FA+ E K +S Sbjct: 412 HAQRDPDYF-PDPEKFIPDRFSMERKGEIS-PFAYTPFSAGPRNCIGQKFAMLEMKSTIS 469 Query: 1533 TILQRFSFELSP 1568 +++ FEL P Sbjct: 470 KMVRH--FELLP 479
>Q9VMT5:C28D1_DROME Probable cytochrome P450 28d1 - Drosophila melanogaster (Fruit fly)| Length = 502 Score = 118 bits (295), Expect = 1e-25 Identities = 106/407 (26%), Positives = 176/407 (43%), Gaps = 20/407 (4%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHF-----GKQRSTRIGRLLANGLANHEGEKWAKHRRILNP 572 P++MV PE +I + F F K ++ +LAN GE W + R + P Sbjct: 82 PQLMVTTPEYAHKIYVSDFRSFHDNEMAKFTDSKTDPILANNPFVLTGEAWKERRAEVTP 141 Query: 573 AFHHEKIKRMLPVFSACCE---EMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG 743 ++K PV C+ E I R AQGL D+C + T +VIS G Sbjct: 142 GLSANRVKAAYPVSLRVCKKFVEYIRRQSLMAPAQGLNAKDLCLCY---TTEVISDCVLG 198 Query: 744 SNFQEGMKIFQLQGELSERLI-QAFQTLF---IPGYWFFPTKNNRRMRAIDREIRMILRG 911 + Q +++R+ Q+F +F + W P + +++ Sbjct: 199 ISAQSFTDNPTPMVGMTKRVFEQSFGFIFYTVVANLWP-PITKFYSVSLFAKDVAAFFYD 257 Query: 912 IIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTS 1091 ++ K + + +Q+ G L+ ++ F G ETT+ Sbjct: 258 LMQKCIQVRRESPAAQQRDDFLNYMLQLQEKKG-----LNAAELTSHTMTFLTDGFETTA 312 Query: 1092 VLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITF 1271 +LT TL+ L+ +P+ Q K REE+ G FE +S L +E LR++ P+ Sbjct: 313 QVLTHTLLFLARNPKEQMKLREEI----GTAELTFEQISELPFTEACIHETLRIFSPVLA 368 Query: 1272 LTRRTYKAMELGG-----IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNA 1436 + + EL +K G +++P+ +HHDP + ++ + F PERF + I+ Sbjct: 369 ARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHDPQYY-EEPQSFKPERFLN-INGG 426 Query: 1437 AKR---PAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSP 1568 AK+ FF FG GPRIC G F+L + K AL I++ F +++P Sbjct: 427 AKKYRDQGLFFGFGDGPRICPGMRFSLTQIKAALVEIVRNFDIKVNP 473
>P14779:CPXB_BACME Bifunctional P-450:NADPH-P450 reductase - Bacillus megaterium| Length = 1049 Score = 117 bits (293), Expect = 2e-25 Identities = 103/373 (27%), Positives = 162/373 (43%), Gaps = 11/373 (2%) Frame = +3 Query: 528 HEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQN 707 HE + W K IL P+F + +K + +++ +WE + + ++V + Sbjct: 93 HE-KNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADE---HIEVPEDMTR 148 Query: 708 LTGDVISRTAFGSNFQEGMK---------IFQLQGELSERLIQAFQTLFIPGYWFFPTKN 860 LT D I F F + + + E +L +A P Y +N Sbjct: 149 LTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPD--DPAY----DEN 202 Query: 861 NRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIED 1040 R+ + + + ++ II ++ + + + + + L E+ Sbjct: 203 KRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHM--------LNGKDPETGEPLDDEN 254 Query: 1041 IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLKI 1220 I + F AG ETTS LL++ L L +P +KA EE P ++ + +LK Sbjct: 255 IRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKY 314 Query: 1221 VTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYP--AGVNLMLPILFIHHDPDIWGKDAR 1394 V M+ E LRL+P + + LGG +YP G LM+ I +H D IWG D Sbjct: 315 VGMVLNEALRLWPTAPAFSLYAKEDTVLGG-EYPLEKGDELMVLIPQLHRDKTIWGDDVE 373 Query: 1395 EFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSY 1574 EF PERF + +A AF PFG G R CIGQ FAL EA + L +L+ F FE +Y Sbjct: 374 EFRPERFE---NPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNY 430 Query: 1575 IHAPYTVITLQPQ 1613 +TL+P+ Sbjct: 431 ELDIKETLTLKPE 443
>Q9V4U9:C6A13_DROME Probable cytochrome P450 6a13 - Drosophila melanogaster (Fruit fly)| Length = 493 Score = 117 bits (293), Expect = 2e-25 Identities = 103/397 (25%), Positives = 175/397 (44%), Gaps = 10/397 (2%) Frame = +3 Query: 405 TPRVMVPDPELVREILSNKFGHF---GKQRSTRIGRLLANGLANHEGEKWAKHRRILNPA 575 T + + D EL+R+I+ F F G + R L N L +G +W R+ L Sbjct: 77 TKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTGN-LLFLDGPEWRWLRQNLTQV 135 Query: 576 FHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG---S 746 F K+K M P E++ + + D+C F T DVI AFG + Sbjct: 136 FTSGKMKFMFPNMVEVGEKLTQACR--LQVGEIEAKDLCARF---TTDVIGSCAFGLECN 190 Query: 747 NFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKK 926 + Q+ F+ G + + ++ + + F + R++R R R + Sbjct: 191 SLQDPESQFRRMGRSVTQ--EPLHSVLVQAFMFAQPELARKLRF--RLFRPEVSEFFLDT 246 Query: 927 ERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTW 1106 R + M+ LS E I + +F+ AG +T+S +++ Sbjct: 247 VRQTLDYRRRENIHRNDLIQLLMELGEEGVKDALSFEQIAAQALVFFLAGFDTSSTTMSF 306 Query: 1107 TLIVLSMHPEWQEKAREEVLHYFGRTTPD--FESLSRLKIVTMIFYEVLRLYPPITFLTR 1280 L L+++P+ QE+ R EVL R ++S+ + + + E LR YP + L R Sbjct: 307 CLYELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLR 366 Query: 1281 RTYKAMEL--GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAA 1454 R+ K ++ + G +++P+ IHHDP+++ D +F+P RF + A+ P A Sbjct: 367 RSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELY-PDPEKFDPSRF-EPEEIKARHPFA 424 Query: 1455 FFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELS 1565 + PFG GPR CIG+ F + K+ L +L+ F F S Sbjct: 425 YLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRS 461
>Q92113:CP17A_SQUAC Cytochrome P450 17A1 - Squalus acanthias (Spiny dogfish)| Length = 509 Score = 117 bits (292), Expect = 2e-25 Identities = 104/425 (24%), Positives = 174/425 (40%), Gaps = 16/425 (3%) Frame = +3 Query: 348 MFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANG--- 518 +F K +G + GP V++ + + +E+L K F + S LL+ G Sbjct: 57 LFQKLQKTYGNLFSLMMGPHYAVVINNHQHAKEVLLKKGKIFAGRPSMVTTDLLSRGGKD 116 Query: 519 -LANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQ----GLCEV 683 G W HR+++ A H + SA E+MI + SM + Sbjct: 117 IAFGKYGPAWKFHRKLVLSALH------LFGDGSAGIEKMICQEATSMCSTFERLNNAAH 170 Query: 684 DVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQ--AFQTLF--IPGYWFFP 851 D+ P+ +VI F S +++ FQ + S+ ++ A +L P FFP Sbjct: 171 DMMPDVTRAVTNVICLLCFNSTYEKEDPEFQTMRKYSQGIVNTVAKDSLIDIFPWLQFFP 230 Query: 852 TKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKAN-LGL 1028 +N ++ IL+ + + N + +N + GL Sbjct: 231 NENLHTLKQCIATRDSILQKKFEDHKANYSSDSANDLFNILLKAKMNAENNNSSVHEAGL 290 Query: 1029 SIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG-RTTPDFESL 1205 + + ++ + AG+ET+S W +I L HPE Q+K +EE+ G TP Sbjct: 291 TDDHMVMTVADIFGAGVETSSTAFAWMIIYLIHHPEVQKKIQEEIDSNIGFERTPKMSDK 350 Query: 1206 SRLKIVTMIFYEVLRLYPPITFLTRRTYKA-MELGGIKYPAGVNLMLPILFIHHDPDIWG 1382 + + +E+LR+ P L A +G P G +++ + IHHD W Sbjct: 351 GNMNFLNATIHEILRIQPVSPLLIPHVALADSSIGDYTIPKGTRVIINLWAIHHDEKEW- 409 Query: 1383 KDAREFNPERFADGISN-AAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 K+ F+P RF D ++ PFG G R+C+G+ A E + S ILQRF+ + Sbjct: 410 KNPDAFDPGRFLDEDGKYVCSSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQRFTVQ 469 Query: 1560 LSPSY 1574 + P Y Sbjct: 470 VPPGY 474
>Q9GMC8:CP17A_FELCA Cytochrome P450 17A1 - Felis silvestris catus (Cat)| Length = 508 Score = 115 bits (288), Expect = 6e-25 Identities = 107/424 (25%), Positives = 185/424 (43%), Gaps = 25/424 (5%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF-GKQRSTRIGRLLAN----GLANH 530 K++G + G VMV D +L +E+L K F G+ + L N A+H Sbjct: 58 KKYGPIYSFRLGTKTTVMVGDHQLAKEVLVKKGKEFSGRPHVVTLDILSDNQKGIAFADH 117 Query: 531 EGEKWAKHRRILNPAFH-----HEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCP 695 G W HR++ F +++++++ C E+ +N G P Sbjct: 118 -GASWQMHRKLALATFALFKDGDQRLEKII------CREISLLCDNLAMQDGQSIDLYLP 170 Query: 696 EFQNLTGDVISRTAFGSNFQEG---MKIFQLQGEL------SERLIQAFQTLFIPGYWFF 848 F +T ++I F S+F+ G +KI Q E + L+ F L I F Sbjct: 171 LFLAVT-NIICLICFNSSFKNGDPALKIIQNYNEGILKTLGKDNLVDIFPVLKI-----F 224 Query: 849 PTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLG- 1025 P K +M+ + +LR I+ K + N N + ++ Sbjct: 225 PNKTLEKMKNYVKNRDELLREILEKHKENFSNDSITNMLDVLIQARMNSDNNGAASDQDS 284 Query: 1026 --LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRT-TPDF 1196 LS + I+ + AG+ETT+ ++ WT+ L HP+ +K +EE+ G + TP Sbjct: 285 KLLSDKHILTTIGDIFGAGVETTTSVVRWTVAFLLHHPQLYKKLQEEIDQNIGFSRTPTM 344 Query: 1197 ESLSRLKIVTMIFYEVLRLYPPI-TFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPD 1373 ++L ++ EVLR+ P T + + +G G N+++ + +HH+ Sbjct: 345 SDRNQLILLEATIREVLRIRPVAPTLIPHKAIMDSSIGEFAVDKGTNVIINLWALHHNEK 404 Query: 1374 IWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 W + +F PERF D + P+ ++ PFG GPR C+G++ A QE + ++ +LQRF Sbjct: 405 EWYRPD-QFMPERFLDPTRSQLISPSLSYLPFGAGPRSCLGESLARQEVFLFMAWLLQRF 463 Query: 1551 SFEL 1562 E+ Sbjct: 464 DLEV 467
>P82711:C6A19_DROME Probable cytochrome P450 6a19 - Drosophila melanogaster (Fruit fly)| Length = 503 Score = 115 bits (288), Expect = 6e-25 Identities = 114/437 (26%), Positives = 185/437 (42%), Gaps = 27/437 (6%) Frame = +3 Query: 414 VMVPDPELVREILSNKFGHFGKQRSTRIGR--LLANGLANHEGEKWAKHRRILNPAFHHE 587 +++ D + V+ +L F F + + L N LA EG+KW R+ L F Sbjct: 82 IVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLATIEGQKWKNLRQKLTHTFTSA 141 Query: 588 KIKRMLPVFSACCEEMITRWEN--SMSAQGLCEVDVCPEFQNLTGDVISRTAFGSN---- 749 K+K M +EMI + S S+Q L D+ F T DVI AFG Sbjct: 142 KMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRF---TSDVIGICAFGLKCNSL 198 Query: 750 -------FQEGMKIFQLQ--GELSERLIQAFQTLFIP-GYWFF-PTKNNRRMRAIDREIR 896 Q G + + G L + LI L + G+ F P+ M+ + I Sbjct: 199 RDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPSVQKFYMKIVQDTID 258 Query: 897 MILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAG 1076 ++ + + + Q G GL+ ++ + +F+ AG Sbjct: 259 YRMKRKVTRND------------FMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAG 306 Query: 1077 METTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP--DFESLSRLKIVTMIFYEVLR 1250 E S + +TL L+ + + Q+K R E+ R +++S+ L + + E LR Sbjct: 307 FEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLR 366 Query: 1251 LYPPITFLTRRTYKAMELGGIKY--PAGVNLMLPILFIHHDPDIWGKDAREFNPERFADG 1424 +P + L R K + KY AG +++ L IHHDP+ + + +F PERF + Sbjct: 367 KHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFY-PEPEKFIPERFDE- 424 Query: 1425 ISNAAKRPA-AFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSP-SYIHAPYTV- 1595 KRP AF PFG GPR CIG F + + L+ ++ F FEL P + + YT+ Sbjct: 425 -EQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTIN 483 Query: 1596 -ITLQPQHGAQIRLKKI 1643 + L + G + + K+ Sbjct: 484 NLLLGSEGGIHLNITKV 500
>Q9VLZ7:C4D21_DROME Probable cytochrome P450 4d21 - Drosophila melanogaster (Fruit fly)| Length = 511 Score = 115 bits (288), Expect = 6e-25 Identities = 114/457 (24%), Positives = 187/457 (40%), Gaps = 28/457 (6%) Frame = +3 Query: 351 FTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANH 530 F + ++GK W + D + ILS+ + L +GL Sbjct: 60 FGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLS 119 Query: 531 EGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNL 710 G KW R++L PAFH + ++ + + M+ + +N A G VD+ Sbjct: 120 TGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNY--ADGKTCVDLFKFVSLE 177 Query: 711 TGDVISRTAFG--------SNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNR 866 DV + TA G NF + + S+RL W FP Sbjct: 178 ALDVTTETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRY----NWLFPLAAPL 233 Query: 867 RMRAIDREIRMI--LRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKA-------- 1016 R + ++I ++ + ++ RAI + GKA Sbjct: 234 VYRRLQKDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDD--DIGGKAKMTLLDIL 291 Query: 1017 ------NLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG 1178 N LS DI +E +F FAG +TT+ ++ L +S HP+ QE EE++ G Sbjct: 292 LQATIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLG 351 Query: 1179 RTTPDFE----SLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLP 1346 PD L LK + + E +RL+PP+ L R + +++G I P +++L Sbjct: 352 -PDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLM 410 Query: 1347 ILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMA 1526 +++ DP+ + D F PER+ D + + P A+ PF GP+ CIGQ FA + K Sbjct: 411 PYYVYRDPEYF-PDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKAL 469 Query: 1527 LSTILQRFSFELSPSYIHAPYTVITLQPQHGAQIRLK 1637 +S +++ + + + A YT I L G + LK Sbjct: 470 ISKVIRHYELLPLGADLKATYTFI-LSSSTGNNVGLK 505
>Q27606:CP4E2_DROME Cytochrome P450 4e2 - Drosophila melanogaster (Fruit fly)| Length = 526 Score = 115 bits (287), Expect = 8e-25 Identities = 124/512 (24%), Positives = 206/512 (40%), Gaps = 56/512 (10%) Frame = +3 Query: 273 SRFNAEARSQPMPPGSHHIAPR---VLPMFTNAIKEHGKVSFT-WFGPTPRVMVPDPELV 440 ++FN R P+ +H + +L + ++GK +F W G V+V + + Sbjct: 31 NKFNGP-RGLPLMGNAHQMGKNPSEILDTVFSWWHQYGKDNFVFWIGTYSNVLVTSSKYL 89 Query: 441 REILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSA 620 ILS++ L GL G KW KHR+++ PAFH ++ V + Sbjct: 90 EFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNE 149 Query: 621 CCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSER 800 + I + + + D + LT DVI TA G + S Sbjct: 150 NSTKFIKHLKTVAAGDNI--FDFQEQAHYLTLDVICDTAMGVSINA-------MENRSSS 200 Query: 801 LIQAFQTLF--IPGYWFFPTKNNRRMRAI---------------DREIRMILRGIIGKKE 929 ++QAF+ + I F P K N + + D +I + I K Sbjct: 201 IVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRIEAHKS 260 Query: 930 RAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWT 1109 A+ + S L+ +++ +E F F G +TT+ +++ Sbjct: 261 GAVSTNAGDEFTRKKMAFLDTLLSSTIDGR-PLNSKELYEEVSTFMFEGHDTTTSGVSFA 319 Query: 1110 LIVLSMHPEWQEKAREEVLHYFGRTT----PDFESLSRLKIVTMIFYEVLRLYPPITFLT 1277 + +LS H + Q K +E G + F+ +S++K + + E R+YP + F+ Sbjct: 320 VYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIG 379 Query: 1278 RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAF 1457 R T K + G P G L L ++ + ++ ++ KD +F PERF P + Sbjct: 380 RFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVF-KDPHKFRPERF----ELEKPGPFEY 434 Query: 1458 FPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPS---------YIHA--------- 1583 PF GPR CIGQ FAL E K +S I++ +FE+ P+ YI Sbjct: 435 VPFSAGPRNCIGQKFALLEIKTVVSKIIR--NFEVLPALDELVSKDGYISTTIGLPDAER 492 Query: 1584 ----PY---------TVITLQPQHGAQIRLKK 1640 PY V+TL+ ++G IRLK+ Sbjct: 493 KKRDPYRHKYDPILSAVLTLKSENGLYIRLKE 524
>Q9V4T3:C4AD1_DROME Probable cytochrome P450 4ad1 - Drosophila melanogaster (Fruit fly)| Length = 516 Score = 115 bits (287), Expect = 8e-25 Identities = 106/445 (23%), Positives = 188/445 (42%), Gaps = 36/445 (8%) Frame = +3 Query: 414 VMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKI 593 +M+ DP ++ ILS+ + + + + L +GL G +W KH+++ PAF I Sbjct: 83 MMLSDPAEIQNILSSSSLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAI 142 Query: 594 KRMLPVFSACCEEMITRWENSMSAQGL---------CEVDVCPEFQNLTG-DVISRTAFG 743 + L V + + + + Q + C +D+ E N TG D S Sbjct: 143 EGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCE--NATGQDSSSLNGET 200 Query: 744 SNFQEGMK-IFQLQGELSERLIQAFQTLF-IPGYWFFPTKNNRRMRAIDREIRMILRGII 917 S+ +K + + E + +++ F LF + Y+ ++ RA+ +R L II Sbjct: 201 SDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSYYM------KQRRALSL-LRSELNRII 253 Query: 918 GKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVL 1097 ++ + ++ + L +II+E F F G + + Sbjct: 254 SQRRHQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIFTGHDPIAAA 313 Query: 1098 LTWTLIVLSMHPEWQEKAREEVLHYFGRT---TPDFESLSRLKIVTMIFYEVLRLYPPIT 1268 +++TL LS H E Q+KA EE FG D L ++ + +I E LRLYP + Sbjct: 314 ISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVP 373 Query: 1269 FLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRP 1448 + R +++ G K +++ ++ + ++ + D F PERF + N Sbjct: 374 LIARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEKYFD-DPCTFRPERFENPTGNVGIEA 432 Query: 1449 AAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTV----------- 1595 PF GPR CI + FA+ + K LS +L+R FE+ P+ P + Sbjct: 433 FKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRR--FEILPAVDGLPPGINDHSREDCVPQ 490 Query: 1596 ----------ITLQPQHGAQIRLKK 1640 +TL+ ++G QIRL+K Sbjct: 491 SEYDPVLNIRVTLKSENGIQIRLRK 515
>Q9W130:CP9C1_DROME Cytochrome P450 9c1 - Drosophila melanogaster (Fruit fly)| Length = 522 Score = 114 bits (284), Expect = 2e-24 Identities = 100/408 (24%), Positives = 175/408 (42%), Gaps = 27/408 (6%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQRST-----RIGRLLANGLANHEGEKWAKHRRILNP 572 P + DPEL+R++ F F R +++ L + +W + R L P Sbjct: 81 PLYYLSDPELIRQVGIKNFDTFTNHRKGITEGFNDTSVISKSLLSLRDRRWKQMRSTLTP 140 Query: 573 AFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG--- 743 F KI++M + C E + + + A G E+++ F T DVI+ AFG Sbjct: 141 TFTSLKIRQMFELIHFCNVEAVDFVQRQLDA-GTSELELKDFFTRYTNDVIATAAFGIQV 199 Query: 744 SNFQE-GMKIFQLQGELSERL----IQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILR 908 ++F++ + F + +SE ++ + +P M +D +++ Sbjct: 200 NSFKDPNNEFFSIGQRISEFTFWGGLKVMLYILMPKLMKALRVPVMDMNNVDYFKKLVFG 259 Query: 909 GIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKA-----NLGLSIEDIIQECKLFYFA 1073 + +KE++I Q+ + ++ + +D++ +C LF+ A Sbjct: 260 AMKYRKEQSIVRPDMIHLLMEAQRQFKAEQEGSAESAAQQDKAEFNDDDLLAQCLLFFSA 319 Query: 1074 GMETTSVLLTWTLIVLSMHPEWQEKAREEVL---HYFGRTTPDFESLSRLKIVTMIFYEV 1244 G ET + L++T L M+PE QEK E+L G D+++L +K + + E Sbjct: 320 GFETVATCLSFTSYELMMNPEVQEKLLAEILAVKEQLGEKPLDYDTLMGMKYLNCVVSES 379 Query: 1245 LRLYPPITFLTRRTYKAMELGGIKYPAGVNLM------LPILFIHHDPDIWGKDAREFNP 1406 LR +PP + R +L + VNL + + +HHDPD + + +F P Sbjct: 380 LRKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDDLVHINVGALHHDPDNF-PEPEQFRP 438 Query: 1407 ERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 ERF D R + PFG G R CIG AL E K + ++ R+ Sbjct: 439 ERF-DEEHKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLIFQLVLRY 485
>Q27698:CP6D1_MUSDO Cytochrome P450 6d1 - Musca domestica (House fly)| Length = 516 Score = 114 bits (284), Expect = 2e-24 Identities = 132/502 (26%), Positives = 207/502 (41%), Gaps = 47/502 (9%) Frame = +3 Query: 276 RFNAEARSQPMPPGS-----HHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELV 440 R E+ +P GS H P L M K H KV + P ++V D EL Sbjct: 26 RLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELA 85 Query: 441 REILSNKFGHF---GKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPV 611 R+IL+ F F G + + AN L EG+ W R L P+F K+K M Sbjct: 86 RQILTTDFNSFHDRGLYVDEKNDPMSAN-LFVMEGQSWRTLRMKLAPSFSSGKLKGMFET 144 Query: 612 FSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG---SNFQEGMKIFQLQ 782 +++ + +++ D+I FG +F F++ Sbjct: 145 VDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRV- 203 Query: 783 GELSERLIQAFQTLFIPGY-----WFFP--TKNNRRMRAIDR---EIRMILRGIIGKKER 932 LS+RL ++ + + + P K R+ A D +R I++ I +E Sbjct: 204 --LSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREE 261 Query: 933 AIKNXXXXXXXXXXXXXXSNMQQSNGKA---------NL-GLSIEDIIQECKLFYFAGME 1082 + N K NL +SI+ I LFY AG E Sbjct: 262 KGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSE 321 Query: 1083 TTSVLLTWTLIVLSMHPEWQEKAREEV--------LHYFGRTTPDFESLSRLKIVTMIFY 1238 TT+ ++T+ L+M+PE +KA+ EV L GR T +E++ +K + + Sbjct: 322 TTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLT--YEAIQDMKYLDLCVM 379 Query: 1239 EVLRLYPPITFLTRRTYKAMELGGIKY--PAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 E R YP + FL R+ + ++ K P +++ +L IH DP + + ++ PER Sbjct: 380 ETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQP-EDYRPER 438 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSP------SY 1574 FAD + PAA+ PFG GPR CI Q + +K+AL+ IL F+ + P + Sbjct: 439 FAD--ESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKF 496 Query: 1575 IHAPYTVITLQPQHGAQIRLKK 1640 AP L P +G + L K Sbjct: 497 HSAP----VLVPVNGLNVGLSK 514
>Q9VFP1:CP6D5_DROME Probable cytochrome P450 6d5 - Drosophila melanogaster (Fruit fly)| Length = 508 Score = 113 bits (283), Expect = 2e-24 Identities = 106/439 (24%), Positives = 186/439 (42%), Gaps = 30/439 (6%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQRSTRIGRL---LANGLANHEGEKWAKHRRILNPAF 578 P ++V D +L ++L F F R + ++ L EG W R L P+F Sbjct: 76 PALLVRDAQLAHDVLVKDFASF-HDRGVYVDEKNDPMSASLFQMEGASWRALRNKLTPSF 134 Query: 579 HHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG---SN 749 K+K M + ++++ + A G E+++ D+I+ T FG + Sbjct: 135 TSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIFGLDVDS 194 Query: 750 FQEGMKIFQLQGELSER-----LIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGI 914 F + FQ+ + R +I+ + PG F K + A +R +R + Sbjct: 195 FADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLEKFFVKIGWKQEATER-MRELSNRT 253 Query: 915 IGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANL-----------GLSIEDIIQECKL 1061 + +E+ N N + N N+ +S + I + L Sbjct: 254 VDLREQ---NNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFL 310 Query: 1062 FYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLH----YFGRTTPDFESLSRLKIVTM 1229 FY AG ETT+ ++TL L+ +PE EKA+E+V + G+ T ++++S +K + Sbjct: 311 FYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLT--YDAISDMKYLEA 368 Query: 1230 IFYEVLRLYPPITFLTRRTYKAMELGGIKY--PAGVNLMLPILFIHHDPDIWGKDAREFN 1403 E R YP + L R K + K G +++ ++ +H D + + D + Sbjct: 369 CILETARKYPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYF-PDPLAYK 427 Query: 1404 PERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHA 1583 PER+ + + + AA+ PFG GPR+CIG K+A++ +L F E+ Sbjct: 428 PERYLENGKDYTQ--AAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEI 485 Query: 1584 PYTV--ITLQPQHGAQIRL 1634 + V I L P+ G +RL Sbjct: 486 EFGVYGIPLMPKSGVPVRL 504
>P27786:CP17A_MOUSE Cytochrome P450 17A1 - Mus musculus (Mouse)| Length = 507 Score = 111 bits (278), Expect = 9e-24 Identities = 121/481 (25%), Positives = 199/481 (41%), Gaps = 32/481 (6%) Frame = +3 Query: 264 PENSRFNAE-ARSQPMPP--GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVP 425 P++ NA+ RS P P GS PR M N K ++G + G T V+V Sbjct: 18 PKSKTPNAKFPRSLPFLPLVGSLPFLPRRGHMHANFFKLQEKYGPIYSLRLGTTTAVIVG 77 Query: 426 DPELVREILSNKFGHF-GKQRSTRIGRLLANGLA---NHEGEKWAKHRRILNPAFH---- 581 +L RE+L K F G+ + +G L G W HR+++ F Sbjct: 78 HYQLAREVLVKKGKEFSGRPQMVTLGLLSDQGKGVAFADSSSSWQLHRKLVFSTFSLFRD 137 Query: 582 HEKIKRML-PVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQE 758 +K+++M+ ++ C+ ++T S L V ++I F +F+ Sbjct: 138 DQKLEKMICQEANSLCDLILTYDGESRDLSTLIFKSVI--------NIICTICFNISFEN 189 Query: 759 GMKIFQLQGELSERLIQAFQTL----FIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKK 926 I +E ++ P FP KN ++ + L + K Sbjct: 190 KDPILTTIQTFTEGIVDVLGHSDLVDIFPWLKIFPNKNLEMIKEHTKIREKTLVEMFEKC 249 Query: 927 ERAIKNXXXXXXXXXXXXXXSNMQQSN---GKANLGLSIEDIIQECKLFYFAGMETTSVL 1097 + + N + +N G+ S + I+ + AG+ETTS + Sbjct: 250 KEKFNSESLSSLTDILIQAKMNAENNNTGEGQDPSVFSDKHILVTVGDIFGAGIETTSSV 309 Query: 1098 LTWTLIVLSMHPEWQEKAREEVLHYFGRT-TPDFESLSRLKIVTMIFYEVLRLYPPITFL 1274 L W L L +PE + K ++E+ Y G + TP F + L ++ EVLR+ P L Sbjct: 310 LNWILAFLVHNPEVKRKIQKEIDQYVGFSRTPSFNDRTHLLMLEATIREVLRIRPVAPLL 369 Query: 1275 TRRTYKA---MELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKR 1445 +KA +G P ++++ + +HHD + W + R F PERF D + Sbjct: 370 I--PHKANIDSSIGEFAIPKDTHVIINLWALHHDKNEWDQPDR-FMPERFLDPTGSHLIT 426 Query: 1446 PA-AFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELS-----PSYIHAPYTVITLQ 1607 P ++ PFG GPR CIG+ A QE + ++ +LQRF F++S P + P V + Sbjct: 427 PTPSYLPFGAGPRSCIGEALARQELFIFMALLLQRFDFDVSDDKQLPCLVGDPKVVFLID 486 Query: 1608 P 1610 P Sbjct: 487 P 487
>Q9W011:C4D20_DROME Probable cytochrome P450 4d20 - Drosophila melanogaster (Fruit fly)| Length = 510 Score = 111 bits (278), Expect = 9e-24 Identities = 112/440 (25%), Positives = 176/440 (40%), Gaps = 24/440 (5%) Frame = +3 Query: 321 HHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIG 500 H A ++ ++GK W + D + ILS+ Q + Sbjct: 50 HLGAENIIGWVGEKFDKYGKTFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLR 109 Query: 501 RLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCE 680 L +GL G KW R+I AFH + ++ + + M+ A G Sbjct: 110 PFLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRK--VADGKTA 167 Query: 681 VDVCPEFQNLTGDVISRTAFG--SNFQEGMKIFQLQGELSERLIQAFQTL-FIPGY-WFF 848 VD+ DVI+ A G N Q ++ S IQ + F Y W F Sbjct: 168 VDMLKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLF 227 Query: 849 PTKNNRRMRAIDREIRMI---LRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKA- 1016 P R + +IR++ +I ++ ++ + + + A Sbjct: 228 PLAAPLLHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMAL 287 Query: 1017 ----------NLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVL 1166 N LS DI +E F F G +TTS ++ L ++ HPE Q++ EE+ Sbjct: 288 LDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQ 347 Query: 1167 HYFGRTTPDFES------LSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAG 1328 G PD + L LK + + E +RLYPP+ + R K +E+G PA Sbjct: 348 RVLG---PDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPAN 404 Query: 1329 VNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFAL 1508 ++ L + + H D + + D F PERF + A+ PF GP+ CIGQ FA+ Sbjct: 405 TSIYLVLYYAHRDANYF-PDPLSFRPERFLED-QEQGHNTFAYVPFSAGPKNCIGQKFAV 462 Query: 1509 QEAKMALSTILQRFSFELSP 1568 E K+ +S +L RF +EL P Sbjct: 463 LEMKVLISKVL-RF-YELLP 480
>P24458:CP52E_CANMA Cytochrome P450 52A5 - Candida maltosa (Yeast)| Length = 523 Score = 111 bits (277), Expect = 1e-23 Identities = 112/447 (25%), Positives = 183/447 (40%), Gaps = 32/447 (7%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWA 548 H T G V+ DPE ++ +L+ +F F R LL +G+ +GE W Sbjct: 87 HHSFYMTVAGMLKIVLTVDPENIKAVLATQFNDFALGARHAHFDPLLGDGIFTLDGEGWK 146 Query: 549 KHRRILNPAFHHEKI---KRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGD 719 R +L P F E+I K + P +++ + Q L F T D Sbjct: 147 HSRAMLRPQFAREQIAHVKALEPHVQVLAKQIKLNKGETFDLQEL--------FFRFTVD 198 Query: 720 VISRTAFGSN----FQEGMKI---FQLQGELSERLIQAFQT----LFIPGY--WFFPTKN 860 + FG + + E + + + G E +AF T L Y F+ N Sbjct: 199 TATEFLFGESVHSLYDEKLGVPPPNNIPGR--ENFAKAFNTSQHYLATRTYSQMFYFLTN 256 Query: 861 NRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIED 1040 + R + ++ + + + K A ++ ++Q+ L + + Sbjct: 257 PKEFRDCNAKVHKLAQYFVNKALDASEDEVAEKSKGGYVFLYELVKQTRDPKVLQDQLLN 316 Query: 1041 IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP------DFES 1202 I+ AG +TT+ LL++ + L+ +P+ K REE+ FG FE+ Sbjct: 317 IM-------VAGRDTTAGLLSFAMFELARNPKIWNKLREEIEVNFGLGEEARVDEISFET 369 Query: 1203 LSRLKIVTMIFYEVLRLYP--PITFLTRRTYKAMELGGIK-------YPAGVNLMLPILF 1355 L + + + + E LR+YP P+ F T + GG K P G +++ + Sbjct: 370 LKKCEYLKAVLNETLRMYPSVPVNFRTATRDTTLPRGGGKDGTSPIFVPKGSSVVYTVYK 429 Query: 1356 IHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALST 1535 H + +GKDA EF PER+ + + K A+ PF GGPRIC+GQ FAL EA ++ Sbjct: 430 THRLEEYYGKDAYEFRPERWFE--PSTRKLGWAYVPFNGGPRICLGQQFALTEASYVITR 487 Query: 1536 ILQRFSFELSPSYIHAPYTVITLQPQH 1616 + Q F S + P I L H Sbjct: 488 LAQMFEHLESKDETYPPNKCIHLTMNH 514
>P77900:CP132_MYCTU Putative cytochrome P450 132 - Mycobacterium tuberculosis| Length = 461 Score = 111 bits (277), Expect = 1e-23 Identities = 101/424 (23%), Positives = 176/424 (41%), Gaps = 19/424 (4%) Frame = +3 Query: 414 VMVPDPELVREILSN------KFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPA 575 V + P+ V +L K +G R+T LL + EG+ WA+HR LN Sbjct: 57 VSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGLNLLTD-----EGDSWARHRGALNST 111 Query: 576 FHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQ 755 F ++ ++ + ++ + G + D+ T V++ F +F Sbjct: 112 FARRHLRGLVGLMIDPIADV-----TAARVPG-AQFDMHQSMVETTLRVVANALFSQDFG 165 Query: 756 EGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGI-IGKKER 932 + Q +L+ R ++ + L G W + D I I G+ + R Sbjct: 166 P---LVQSMHDLATRGLRRAEKLERLGLWGLMPRT-----VYDTLIWCIYSGVHLPPPLR 217 Query: 933 AIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSI-----------EDIIQECKLFYFAGM 1079 ++ + + A+L L++ + + E F AG Sbjct: 218 EMQEITLTLDRAINSVIDRRLAEPTNSADL-LNVLLSADGGIWPRQRVRDEALTFMLAGH 276 Query: 1080 ETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIFYEVLRLYP 1259 ETT+ ++W +++++P+ ++ E+ G P + L +L T E R + Sbjct: 277 ETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFS 336 Query: 1260 PITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAA 1439 + + R + G + G +++PI IHHDP W D F+P RF + Sbjct: 337 SVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRF---LRCPT 392 Query: 1440 KRP-AAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQPQH 1616 RP A+ PFGGG RICIGQ+FAL E + + + Q F+F+L+P Y +TL+P+H Sbjct: 393 DRPRCAYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKH 452 Query: 1617 GAQI 1628 G + Sbjct: 453 GVHV 456
>P59954:CP132_MYCBO Putative cytochrome P450 132 - Mycobacterium bovis| Length = 461 Score = 110 bits (276), Expect = 2e-23 Identities = 100/424 (23%), Positives = 174/424 (41%), Gaps = 19/424 (4%) Frame = +3 Query: 414 VMVPDPELVREILSN------KFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPA 575 V + P+ V +L K +G R+T LL + EG+ WA+HR LN Sbjct: 57 VSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGLNLLTD-----EGDSWARHRGALNST 111 Query: 576 FHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQ 755 F ++ ++ + ++ + D+ T V++ F +F Sbjct: 112 FARRHLRGLVGLMIDPIADVTAALVPG------AQFDMHQSMVETTLRVVANALFSQDFG 165 Query: 756 EGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGI-IGKKER 932 + Q +L+ R ++ + L G W + D I I G+ + R Sbjct: 166 P---LVQSMHDLATRGLRRAEKLERLGLWGLMPRT-----VYDTLIWCIYSGVHLPPPLR 217 Query: 933 AIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSI-----------EDIIQECKLFYFAGM 1079 ++ + + A+L L++ + + E F AG Sbjct: 218 EMQEITLTLDRAINSVIDRRLAEPTNSADL-LNVLLSADGGIWPRQRVRDEALTFMLAGH 276 Query: 1080 ETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIFYEVLRLYP 1259 ETT+ ++W +++++P+ ++ E+ G P + L +L T E R + Sbjct: 277 ETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFS 336 Query: 1260 PITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAA 1439 + + R + G + G +++PI IHHDP W D F+P RF + Sbjct: 337 SVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRF---LRCPT 392 Query: 1440 KRP-AAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQPQH 1616 RP A+ PFGGG RICIGQ+FAL E + + + Q F+F+L+P Y +TL+P+H Sbjct: 393 DRPRCAYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKH 452 Query: 1617 GAQI 1628 G + Sbjct: 453 GVHV 456
>Q9VMS9:C4AC1_DROME Probable cytochrome P450 4ac1 - Drosophila melanogaster (Fruit fly)| Length = 509 Score = 110 bits (275), Expect = 2e-23 Identities = 103/389 (26%), Positives = 173/389 (44%), Gaps = 11/389 (2%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 L +GL KW R+ L PAFH ++ L +F C++ + E ++ A+ L Sbjct: 127 LGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKNLDAE-LELNQ 185 Query: 687 VCPEFQNLTGDVISRTAFG---SNFQEGMKIFQLQGELSERLIQAF-QTLFIPGYWFFPT 854 V P F T + I TA G + EG + + + E LIQ L ++FF Sbjct: 186 VIPPF---TLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYFFVY 242 Query: 855 KNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQS--NGKANLGL 1028 + R+ R + II +K + + M + +A+ + Sbjct: 243 GDYRKHLQNLRIVHDFSSRIIERKRQQFQQKQLGEVDEFGRKQRYAMLDTLLAAEADGQI 302 Query: 1029 SIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLS 1208 + I E F F G +TTS L +TL++L++H + Q+K EEV + + D Sbjct: 303 DHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVEN-LPEDSDDISMFQ 361 Query: 1209 RLKIVTM--IFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWG 1382 K+V + + E LR++P + F+ R+ + + G+ P + + I I DP + Sbjct: 362 FNKLVYLECVIKESLRMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFP 421 Query: 1383 KDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 K F P+RF + + P A+ PF G R CIGQ FA+ E K+ L+ +++ +F+L Sbjct: 422 KPDL-FQPDRFLPE-NTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIR--NFKL 477 Query: 1563 SPSYIHAPYTV---ITLQPQHGAQIRLKK 1640 P+ T I L+ Q +++L K Sbjct: 478 LPATQLEDLTFENGIVLRTQENIKVKLSK 506
>Q9VYT8:C28C1_DROME Probable cytochrome P450 28c1 - Drosophila melanogaster (Fruit fly)| Length = 505 Score = 110 bits (275), Expect = 2e-23 Identities = 69/190 (36%), Positives = 101/190 (53%), Gaps = 7/190 (3%) Frame = +3 Query: 1020 LGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV-LHYFGRTTPDF 1196 L LS ED+ F F G++TTS + L++L +P+ Q + EE+ L G PD Sbjct: 283 LDLSEEDMASHAMTFMFDGLDTTSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDL 342 Query: 1197 ESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGG------IKYPAGVNLMLPILFI 1358 ++L L ++ F E LR+YP + ++ K EL G +K G ++M+PI + Sbjct: 343 DALIDLPYLSACFNESLRIYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIYAL 402 Query: 1359 HHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTI 1538 H+DPD++ + F PERF DG K+ F FG GPR C+G L AK AL+ I Sbjct: 403 HNDPDLY-PEPDVFRPERFLDGGLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAALAAI 461 Query: 1539 LQRFSFELSP 1568 +QRF +SP Sbjct: 462 VQRFEVVVSP 471
>Q9Y758:CP52M_DEBHA Cytochrome P450 52A13 - Debaryomyces hansenii (Yeast) (Torulaspora| hansenii) Length = 519 Score = 110 bits (274), Expect = 3e-23 Identities = 109/439 (24%), Positives = 177/439 (40%), Gaps = 30/439 (6%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHH 584 P ++ DPE ++ +L+ +F F R LL +G+ +G W + R +L P F Sbjct: 96 PVIITRDPENMKAVLATQFNDFALGTRHAHFKPLLGDGIFTLDGNGWKQSRSMLRPQFSR 155 Query: 585 EKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQE-- 758 E++ + + E + R + +++ F LT D + FG + Sbjct: 156 EQVAHVQAL-----EPHLQRLAKHIRLADGETINIQDLFFKLTVDTATEFLFGQSVYSLK 210 Query: 759 -------GMKIFQLQGELSERLIQAFQTLFIPGY--WFFPTKNNRRMRAIDREIRMILRG 911 + F + + A L Y F+ NN R +++ R Sbjct: 211 DAAINDPPTEDFDGRSSFANSFNTAQTYLGTRAYLQMFYFIVNNSDFRKCCKQVHDFTRF 270 Query: 912 IIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTS 1091 + K ++Q+ L + +I+ AG +TT+ Sbjct: 271 YVQKGLDMTPEELEKKSENGYVFLYELVKQTRDPKVLQDQLLNIL-------LAGRDTTA 323 Query: 1092 VLLTWTLIVLSMHPEWQEKAREEVLHYFGR------TTPDFESLSRLKIVTMIFYEVLRL 1253 LL++T L+ HP K +EE+ FG+ + FESL + + + + E+LRL Sbjct: 324 GLLSFTFFELARHPRVFNKLKEEIYEAFGKGDDARVSEITFESLKKCEYLKWVMNEMLRL 383 Query: 1254 YP--PITFLTRRTYKAMELGG-------IKYPAGVNLMLPILFIHHDPDIWGKDAREFNP 1406 YP P+ F + GG I G + + H + +GKDA EF P Sbjct: 384 YPSVPVNFRVATKRTTLPRGGGPDGNSPIYVGKGTTVAYSVYSTHRMEEYYGKDADEFKP 443 Query: 1407 ERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF-SFELSPS--YI 1577 ER+A+ + K A+ PF GGPRIC+GQ FAL EA ++ +LQ F EL Y Sbjct: 444 ERWAE----SRKLGWAYVPFNGGPRICLGQQFALTEASYIVTRLLQMFDKLELHDDRPYP 499 Query: 1578 HAPYTVITLQPQHGAQIRL 1634 A +T+ Q G + L Sbjct: 500 PAKSVHLTMCHQDGVYVSL 518
>O57525:CP17A_RANDY Cytochrome P450 17A1 - Rana dybowskii (Dybovsky's frog) (Korean brown| frog) Length = 519 Score = 110 bits (274), Expect = 3e-23 Identities = 112/437 (25%), Positives = 186/437 (42%), Gaps = 24/437 (5%) Frame = +3 Query: 324 HIAPRVLP--MFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRI 497 H+ ++ P +F N K++G + G V+V + E RE+L K FG + T Sbjct: 56 HLGKKLPPHILFCNLQKKYGSLYSFMMGSHYVVVVNNHEDAREVLLKKGKTFGGRPRT-- 113 Query: 498 GRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVF---SACCEEMITRWENSMSAQ 668 + + +G+ A FH + + L +F + E++I+R A Sbjct: 114 ---VTTDILTRDGKDIAFADYSPTWKFHRKMVHSALCMFGEGTVAIEQIISR-----EAA 165 Query: 669 GLCE---------VDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQ--AF 815 LC+ +D+ PE +V+ F + ++ G F+ + S+ ++ A Sbjct: 166 SLCQTLTSFQRIPLDMAPELIRAVTNVVCSLCFNTRYKRGDAEFETMLKYSKGIVDTVAK 225 Query: 816 QTL--FIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXS 989 +L P FP K+ +R +L+ I + + A Sbjct: 226 DSLVDIFPWLQIFPNKDLDILRQSVAARDQLLQKKINEHKDAFCGETVKDLVDALLKAKL 285 Query: 990 NMQQSNGKAN--LGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREE- 1160 NM+ +N + +GL+ + I+ + AG+ETTS +L W + L +PE Q+K +EE Sbjct: 286 NMENNNSNVSQDVGLTEDHILMTVGDIFGAGVETTSTVLKWAVAYLLHYPEVQKKIQEEL 345 Query: 1161 -VLHYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRT-YKAMELGGIKYPAGVN 1334 V FGR P L EVLR+ P L K +G P Sbjct: 346 DVKVGFGRY-PLLSDRKILHYTEAAISEVLRIRPVSPLLIPHVALKESSIGEYTIPKEAR 404 Query: 1335 LMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFALQ 1511 +++ + +HHD W + F+P+RF D N P+ +F PFG G R+C+G+ A Sbjct: 405 VVINLWSLHHDEKEW-VNPHLFSPDRFLDENGNRVYSPSPSFLPFGAGIRVCLGEALAKM 463 Query: 1512 EAKMALSTILQRFSFEL 1562 E + LS ILQRF+ E+ Sbjct: 464 EVFLFLSWILQRFTLEV 480
>Q9V9L1:CP6W1_DROME Probable cytochrome P450 6w1 - Drosophila melanogaster (Fruit fly)| Length = 514 Score = 109 bits (273), Expect = 3e-23 Identities = 94/404 (23%), Positives = 170/404 (42%), Gaps = 21/404 (5%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGK---QRSTRIGRLLANGLANHEGEKWAKHRRILNPAF 578 P +++ D EL++ ++ KF +F Q L L W + R ++P F Sbjct: 79 PALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDALGYKNLFFARSPGWRELRTKISPVF 138 Query: 579 HHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG---SN 749 KIK+M P+ + + E S + D+C F T D+I+ AFG + Sbjct: 139 TSGKIKQMYPLMVKIGKNLQDSAERLGSGTEVQVKDLCSRF---TTDLIATIAFGVEANA 195 Query: 750 FQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGK-- 923 Q+ F L + F + + R++ RE +R + Sbjct: 196 LQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPALASLARVKLFSRETTKFIRSSVNYVL 255 Query: 924 KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLT 1103 KER + GK + + ++ ++ + +F AG ET++ +T Sbjct: 256 KERERTGEKRNDLIDILLALKREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMT 315 Query: 1104 WTLIVLSMHPEWQEKAREEVLHYFG-RTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTR 1280 TL L+ + Q++ R+E++ +FG +E + + ++ + E LR YP + ++ R Sbjct: 316 MTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIER 375 Query: 1281 RTYKAME--------LGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNA 1436 + E ++ P G+++ + + +H DP W D +++PERF N+ Sbjct: 376 ECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYW-PDPEKYDPERF-----NS 429 Query: 1437 AKRP----AAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 + R A+ PFG GPR CIG L ++K+ L IL+ F Sbjct: 430 SNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRF 473
>Q12588:CP52J_CANMA Cytochrome P450 52A10 - Candida maltosa (Yeast)| Length = 519 Score = 109 bits (273), Expect = 3e-23 Identities = 115/423 (27%), Positives = 174/423 (41%), Gaps = 32/423 (7%) Frame = +3 Query: 414 VMVPDPELVREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEK 590 + DPE ++ +L+ +F + QR + LL G+ +G W R +L P F ++ Sbjct: 97 IATKDPENIKAMLATQFNEYTLGQRLNFLAPLLGKGIFTLDGNGWKHSRAMLRPQFSRDQ 156 Query: 591 I---KRMLPVFSACCEEMITRWENSMSAQGLC---EVDVCPEFQNLTGDVISRT---AFG 743 I K + P F + +I Q L VD EF L G+ +S + G Sbjct: 157 IGHVKMLEPHFQLLKKHIIKNKGTFFDIQELFFRFTVDSATEF--LFGESVSSLKDESIG 214 Query: 744 SNFQE----GMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIR--MIL 905 + +E G K F S+ + +TL YW + + +R I + I Sbjct: 215 YDQEEIDFAGRKDFAEAFNKSQVYLST-RTLLQLLYWLVNSADFKRCNKIVHKFSDYYIK 273 Query: 906 RGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMET 1085 + + E K+ + + N+ L AG +T Sbjct: 274 KALTATPEELEKHSSYIFLYELAKQTRDPIVLRDQSLNILL--------------AGRDT 319 Query: 1086 TSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD------FESLSRLKIVTMIFYEVL 1247 T+ LL++ + L +PE K R+E+ H FG + FE L + + + E L Sbjct: 320 TAGLLSFAVFELGRNPEVWSKLRQEIGHKFGLDSYSRVEDISFELLKLCEYLKAVLNETL 379 Query: 1248 RLYPPITFLTRRTYKAMEL---GG------IKYPAGVNLMLPILFIHHDPDIWGKDAREF 1400 RLYP + R K L GG I G +M + + D +GKDA EF Sbjct: 380 RLYPSVPRNARFAAKNTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYGKDANEF 439 Query: 1401 NPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF-SFELSPSYI 1577 PER+ + K AF PF GGPRIC+GQ FAL EA L+ ++Q F + ELSP Sbjct: 440 RPERWFE--PEVRKLGWAFLPFNGGPRICLGQQFALTEASYVLARLIQSFETLELSPEAA 497 Query: 1578 HAP 1586 + P Sbjct: 498 YPP 500
>Q59990:CP120_SYNY3 Putative cytochrome P450 120 - Synechocystis sp. (strain PCC 6803)| Length = 444 Score = 109 bits (272), Expect = 4e-23 Identities = 116/462 (25%), Positives = 187/462 (40%), Gaps = 15/462 (3%) Frame = +3 Query: 297 SQPMPPGSHHIAPRVLPMFTNAIK-----EHGKVSFTWFGPT--PRVMVPDPELVREILS 455 S P+PPG LP + + GK FGP R+ + + L+ Sbjct: 10 SLPIPPGDFG-----LPWLGETLNFLNDGDFGKKRQQQFGPIFKTRLFGKNVIFISGALA 64 Query: 456 NKFGHFGKQR--------STRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPV 611 N+F +Q STRI L N LA GE R+IL AF + LP Sbjct: 65 NRFLFTKEQETFQATWPLSTRI-LLGPNALATQMGEIHRSRRKILYQAFLPRTLDSYLPK 123 Query: 612 FSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGEL 791 + + +W + EV P+ + +T DV + G + ++F Sbjct: 124 MDGIVQGYLEQWGKAN------EVIWYPQLRRMTFDVAATLFMGEKVSQNPQLFPW---- 173 Query: 792 SERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXX 971 F+T +I G + P + + R +L + + E+ IK Sbjct: 174 -------FET-YIQGLFSLPIPLPNTLFGKSQRARALL---LAELEKIIKARQQQPPSEE 222 Query: 972 XXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKA 1151 + + N LS+ ++ + L FAG ET + L+ ++L H + +E+ Sbjct: 223 DALGI--LLAARDDNNQPLSLPELKDQILLLLFAGHETLTSALSSFCLLLGQHSDIRERV 280 Query: 1152 REEVLHYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGV 1331 R+E E+L ++ + + EVLRL PP+ R + + G +P G Sbjct: 281 RQEQNKLQLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGGFRELIQDCQFQGFHFPKGW 340 Query: 1332 NLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQ 1511 + I H DPD++ D +F+PERF S P A PFGGG R C+G+ FA Sbjct: 341 LVSYQISQTHADPDLY-PDPEKFDPERFTPDGSATHNPPFAHVPFGGGLRECLGKEFARL 399 Query: 1512 EAKMALSTILQRFSFELSPSYIHAPYTVITLQPQHGAQIRLK 1637 E K+ + ++Q+F + L P V+T P+ +R+K Sbjct: 400 EMKLFATRLIQQFDWTLLPG--QNLELVVTPSPRPKDNLRVK 439
>O08394:CYPD_BACSU Probable bifunctional P-450:NADPH-P450 reductase 1 [Includes:| Cytochrome P450 102 - Bacillus subtilis Length = 1061 Score = 108 bits (271), Expect = 6e-23 Identities = 113/415 (27%), Positives = 167/415 (40%), Gaps = 16/415 (3%) Frame = +3 Query: 414 VMVPDPELVREILSNKFGHFGKQRSTRIGRLLA---NGLAN---HEGEKWAKHRRILNPA 575 ++V ELV+E+ + F K + ++ A +GL HE W K IL P Sbjct: 52 IVVSGHELVKEVCDEE--RFDKSIEGALEKVRAFSGDGLFTSWTHE-PNWRKAHNILMPT 108 Query: 576 FHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQ 755 F +K ++I +W + VDV + LT D I F F Sbjct: 109 FSQRAMKDYHEKMVDIAVQLIQKWARLNPNEA---VDVPGDMTRLTLDTIGLCGFNYRFN 165 Query: 756 EGMK------IFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGII 917 + I + L E + Q Q L + TK R+ R ++ + Sbjct: 166 SYYRETPHPFINSMVRALDEAMHQ-MQRLDVQDKLMVRTK---------RQFRYDIQTMF 215 Query: 918 GKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVL 1097 + I + + + L E+I + F AG ETTS L Sbjct: 216 SLVDSIIAERRANGDQDEKDLLARMLNVEDPETGEKLDDENIRFQIITFLIAGHETTSGL 275 Query: 1098 LTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLT 1277 L++ L HP+ +KA EEV P ++ + L + MI E LRL+P + Sbjct: 276 LSFATYFLLKHPDKLKKAYEEVDRVLTDAAPTYKQVLELTYIRMILNESLRLWPTAPAFS 335 Query: 1278 RRTYKAMELGGIKYPAGVNLMLPILF--IHHDPDIWGKDAREFNPERF--ADGISNAAKR 1445 + +GG K+P N + +L +H D D WGKDA EF PERF D + + Sbjct: 336 LYPKEDTVIGG-KFPITTNDRISVLIPQLHRDRDAWGKDAEEFRPERFEHQDQVPH---- 390 Query: 1446 PAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQP 1610 A+ PFG G R CIG FAL EA + L IL+ F+ +Y +TL+P Sbjct: 391 -HAYKPFGNGQRACIGMQFALHEATLVLGMILKYFTLIDHENYELDIKQTLTLKP 444
>Q27594:CP6A9_DROME Cytochrome P450 6a9 - Drosophila melanogaster (Fruit fly)| Length = 504 Score = 108 bits (271), Expect = 6e-23 Identities = 103/410 (25%), Positives = 185/410 (45%), Gaps = 18/410 (4%) Frame = +3 Query: 387 FTWFGPTPRVMVPDPELVREILSNKFGHF---GKQRSTRIGRLLANGLANHEGEKWAKHR 557 F WF P ++V D L + IL +F F G +T L + L +G+KW R Sbjct: 75 FYWF-QRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPL-SGQLFLLDGQKWKSMR 132 Query: 558 RILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEV-DVCPEFQNLTGDVISRT 734 L+ F K+K M P E I + +M + EV D+ F T DVI Sbjct: 133 SKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARF---TTDVIGTC 189 Query: 735 AFG---SNFQEGMKIFQLQGE--LSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDRE--- 890 AFG S+ ++ F++ G + E+ FI + + + ++ + E Sbjct: 190 AFGIECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQNLARRLHMKITLEEAEHFF 249 Query: 891 IRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYF 1070 +R++ + +++ I+ S + +S ++ L+IE++ + +F+ Sbjct: 250 LRIVRETVAFREKNNIRRNDFMDQLIDLKN--SPLTKSESGESVNLTIEEMAAQAFVFFG 307 Query: 1071 AGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD--FESLSRLKIVTMIFYEV 1244 AG ET+S + + L L+ H + Q++ R+E G+ + +ES+ + + + E Sbjct: 308 AGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISET 367 Query: 1245 LRLYPPITFLTRRTYKAMELGGI-KY--PAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 LRLY + L R + E+ G KY G+ +++P +H D ++ + FNP+ F Sbjct: 368 LRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYA-NPNTFNPDNF 426 Query: 1416 ADGISNAAKRPAA-FFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + +R + + PFG GPR CIG F +A+ L+ ++ RF F + Sbjct: 427 SP--ERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSV 474
>Q12589:CP52K_CANMA Cytochrome P450 52A11 - Candida maltosa (Yeast)| Length = 519 Score = 108 bits (271), Expect = 6e-23 Identities = 122/445 (27%), Positives = 184/445 (41%), Gaps = 37/445 (8%) Frame = +3 Query: 414 VMVPDPELVREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEK 590 + DPE ++ +L+ +F F QR + LL G+ +GE W R +L P F ++ Sbjct: 97 IATKDPENIKAMLATQFNDFTLGQRLSYFAPLLGKGIFTLDGEGWKHSRAMLRPQFSRDQ 156 Query: 591 I---KRMLPVFSACCEEMITRWENSMSAQGLC---EVDVCPEFQNLTGDVISRT---AFG 743 + K + P F + +I + Q L VD EF L G+ +S + G Sbjct: 157 VGHVKMLEPHFQLLKKHIIKNKGSFFDIQELFFRFTVDSATEF--LFGESVSSLKDESIG 214 Query: 744 SNFQE----GMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIR--MIL 905 + +E G K F S+ + L + YW + + +R I + I Sbjct: 215 YDQEEIDFAGRKDFAEAFNKSQVYLSTRSLLQLL-YWLVNSSDFKRCNKIVHKFSDYYIK 273 Query: 906 RGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMET 1085 + + E K+ + + N+ L AG +T Sbjct: 274 KALTATPEELEKHSSYIFLYELAKQTRDPIVLRDQSLNILL--------------AGRDT 319 Query: 1086 TSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD-------FESLSRLKIVTMIFYEV 1244 T+ LL++ + L +PE K REE+ FG PD FE L + + + E Sbjct: 320 TAGLLSFAVFELGRNPEVWSKLREEIGDKFG-LDPDSRIEDISFELLKLCEYLKAVINET 378 Query: 1245 LRLYPPIT----FLTRRTYKAMELGG-------IKYPAGVNLMLPILFIHHDPDIWGKDA 1391 LRLYP + F T + GG I G +M + + D +GKDA Sbjct: 379 LRLYPSVPRNGRFAAANT--TLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYGKDA 436 Query: 1392 REFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF-SFELSP 1568 EF PER+ + K AF PF GGPRIC+GQ FAL EA L ++Q F + ELSP Sbjct: 437 NEFRPERWFE--PEVRKLGWAFLPFNGGPRICLGQQFALTEASYVLVRLIQSFETLELSP 494 Query: 1569 S--YIHAPYTVITLQPQHGAQIRLK 1637 Y A T +T+ GA +R++ Sbjct: 495 DAPYPPAKLTHLTMCLFDGAPVRIE 519
>O73853:CP17A_ICTPU Cytochrome P450 17A1 - Ictalurus punctatus (Channel catfish)| Length = 514 Score = 108 bits (271), Expect = 6e-23 Identities = 105/425 (24%), Positives = 183/425 (43%), Gaps = 21/425 (4%) Frame = +3 Query: 351 FTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF-GKQRSTRIGRLLANGLAN 527 F K++G + G ++V + +E+L K F G+ R+ L +G Sbjct: 58 FQQLQKKYGDIYSLDMGSNRVIIVNNHHHAKEVLLRKGKIFAGRPRTVTTDILTRDGKDI 117 Query: 528 HEGE---KWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEV----- 683 G+ W HR+I++ A M +A E++I R +SM CE+ Sbjct: 118 AFGDYSATWKFHRKIVHGALC------MFGEGTASIEKIICREASSM-----CEILTNLQ 166 Query: 684 ----DVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQ--AFQTL--FIPGY 839 D+ PE +V+ F S+++ G F+ + S+ ++ A +L P Sbjct: 167 SSAADLAPELTRAVTNVVCTLCFSSSYKRGDPEFEAMLKYSQGIVDTVAKDSLVDIFPWL 226 Query: 840 WFFPTKNNRRMR-AIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKA 1016 FP ++ R +R + +++ + K N S+ + Sbjct: 227 QLFPNEDLRILRRCVSIRDKLLQKKYEEHKADFSDNIQRDLFDALLRAKNSSENNNTSTQ 286 Query: 1017 NLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTT-PD 1193 ++GL+ + ++ + AG+ETT+ +L W+++ L HP+ Q K +EE+ GR P Sbjct: 287 DVGLTDDHLLMTVGDIFGAGVETTTTVLKWSILYLIHHPQVQRKIQEELDAKIGRDRHPQ 346 Query: 1194 FESLSRLKIVTMIFYEVLRLYPPITFLTRR-TYKAMELGGIKYPAGVNLMLPILFIHHDP 1370 L + EVLR+ P L +G G +++ + +HHD Sbjct: 347 VNDRGNLPYLEATIREVLRIRPVSPLLIPHVALSDANIGEYTVQKGTRVIVNLWSLHHDE 406 Query: 1371 DIWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFALQEAKMALSTILQR 1547 W K+ FNPERF + N+ P+ ++ PFG G R+C+G+ A E + LS ILQR Sbjct: 407 KEW-KNPELFNPERFLNEEGNSLCCPSLSYLPFGAGVRVCLGEALAKLELFLFLSWILQR 465 Query: 1548 FSFEL 1562 F+ E+ Sbjct: 466 FTLEV 470
>Q9VMT6:C28D2_DROME Probable cytochrome P450 28d2 - Drosophila melanogaster (Fruit fly)| Length = 501 Score = 108 bits (271), Expect = 6e-23 Identities = 99/409 (24%), Positives = 172/409 (42%), Gaps = 22/409 (5%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQR-----STRIGRLLANGLANHEGEKWAKHRRILNP 572 P+++V PE + +I + F F + + +L N G++W + R + P Sbjct: 82 PQLLVMCPEYIHKIYATDFRSFHNNEWRNFVNKKTDMILGNNPFVLTGDEWKERRSEIMP 141 Query: 573 AFHHEKIKRMLPVFSACCE---EMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG 743 A ++K + PV + C+ E I R + +++GL +D+ + T +V+S G Sbjct: 142 ALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEGLDAMDLSLCY---TTEVVSDCGLG 198 Query: 744 SNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAI------DREIRMIL 905 + Q L + + + F T F ++ T +++R ++E + Sbjct: 199 VSAQS---FTDTPTPLLKMIKRVFNTSFEFIFYSVVTNLWQKVRKFYSVPFFNKETEVFF 255 Query: 906 RGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMET 1085 II R I +Q K GL ++I+ F G ET Sbjct: 256 LDII---RRCITLRLEKPEQQRDDFLNYMLQLQEKK---GLHTDNILINTMTFILDGFET 309 Query: 1086 TSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPI 1265 T+++L +++L +PE Q+K R+E+ G F+ +S L + YE LRL+ P Sbjct: 310 TALVLAHIMLMLGRNPEEQDKVRKEI----GSADLTFDQMSELPHLDACIYETLRLFSPQ 365 Query: 1266 TFLTRRTYKAMELGG-----IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGIS 1430 + + E + G + +P+ +HHDP + +D F PERF + Sbjct: 366 VAARKLVTEPFEFANKNGRTVHLKPGDVVTIPVKALHHDPQYY-EDPLTFKPERFLESNG 424 Query: 1431 NAAKR---PAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSP 1568 K + FG GPR C G FAL + K AL IL+ F +++P Sbjct: 425 GGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIKVNP 473
>Q9Y757:CP52L_DEBHA Cytochrome P450 52A12 - Debaryomyces hansenii (Yeast) (Torulaspora| hansenii) Length = 519 Score = 108 bits (270), Expect = 8e-23 Identities = 112/465 (24%), Positives = 188/465 (40%), Gaps = 39/465 (8%) Frame = +3 Query: 357 NAIKEH----GKVSFTW-FGPTPRVMVPDPELVREILSNKFGHFGK-QRSTRIGRLLANG 518 N IKE GK +F++ TP + +PE ++ +L+ +F F R + LL +G Sbjct: 72 NFIKERFETVGKDTFSFRIAGTPVISTKNPENIKALLATQFSDFALGTRHAQFKPLLGDG 131 Query: 519 LANHEGEKWAKHRRILNPAFHHEKI---KRMLPVFSACCEEMITRWENSMSAQGLCEVDV 689 + +G W R +L P F E++ K + P + + + Q L Sbjct: 132 IFTLDGSGWKHSRAMLRPQFAREQVAHVKSLEPHIQMLAKHVRRAKGGAFDVQSL----- 186 Query: 690 CPEFQNLTGDVISRTAFGSNFQE------GMKIFQLQGELSERLIQAFQTLFI------- 830 F LT D + FG + + GM + + +AF T + Sbjct: 187 ---FFRLTVDSATEFLFGESVESLQDESIGMAKDAVDFDGKAGFAEAFNTAQVYLSIRSL 243 Query: 831 --PGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQS 1004 Y+ NN+ R+ + ++ + K + ++Q+ Sbjct: 244 AQKAYFLV---NNKEFRSSNEKVHKFADYYVQKALNSSPEELEKHSQDGYIFLYELVKQT 300 Query: 1005 NGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRT 1184 L + +I+ AG +TT+ LL++T L+ +P+ K +EE+ FG+ Sbjct: 301 RDPHVLRDQLLNIL-------LAGRDTTAGLLSFTFYELARNPQVWLKLKEEIYEKFGKG 353 Query: 1185 TP------DFESLSRLKIVTMIFYEVLRLYP--PITFLTRRTYKAMELGG-------IKY 1319 FESL + + + + EVLRLYP P F + ++ GG I Sbjct: 354 DDARLEDITFESLKKCEYLKALLNEVLRLYPSVPQNFRVAQKDTSLPRGGGPNRDQPIFI 413 Query: 1320 PAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQN 1499 G + + +H D +GKD+ F PER+ + K AF PF GGPRIC+GQ Sbjct: 414 AKGQTVTYTVYAMHRDEQFYGKDSEVFRPERWFE--PETRKLGWAFLPFNGGPRICLGQQ 471 Query: 1500 FALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQPQHGAQIRL 1634 FAL EA ++ + Q F S + P L H +++++ Sbjct: 472 FALTEASYVIARLAQLFPNLASHDDEYPPRKASHLTMCHQSEVKI 516
>Q9SAB6:C71AI_ARATH Cytochrome P450 71A18 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 108 bits (270), Expect = 8e-23 Identities = 102/423 (24%), Positives = 179/423 (42%), Gaps = 24/423 (5%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANG----LANHEGE 539 +G + FG P ++V E EIL F + ++ L NG + GE Sbjct: 64 YGPLMLLHFGRVPILVVSSSEAAHEILKTHDLKFANRPKSKAVHGLMNGGRDVVFGPYGE 123 Query: 540 KWAKHRRILNPAFHHEKIKRMLPVFSACCEE----MITRWEN---SMSAQGLCEVDVCPE 698 W R++ + + +M+ F EE M+ + E S SA+ L E+ Sbjct: 124 YW---RQMKSVCILNLLTNKMVASFEKVREEEVNAMMEKLEKASCSSSAENLSEL----- 175 Query: 699 FQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTL-------FIPGYWFFPTK 857 F LT DV SR + G + E + G L +R+ Q + L ++P + Sbjct: 176 FVTLTSDVTSRVSLGKKYWED----ETAGGLKKRVRQIMELLREFPIGDYVPALAWIDRI 231 Query: 858 N--NRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLS 1031 N N ++ + R ++ ++ + A ++ N + ++ Sbjct: 232 NGFNSKIVEVSRAYSDLMEKVVQEHLEAGEHKADFVNILLSIEKEKNNGFKVQRNDIKFM 291 Query: 1032 IEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV---LHYFGRTTPDFES 1202 I D+ + G+ T+S LL W + L +PE +K + E+ + G + E Sbjct: 292 ILDM-------FIGGISTSSTLLEWIMTELIRNPECMKKLQNEIRSTIRPHGSYIKEKE- 343 Query: 1203 LSRLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIW 1379 + ++ + + EV R++PP+ L R + +++ G AG +++ IH DP IW Sbjct: 344 VENMRYLKAVIKEVFRVHPPLPLILPRLLTEDVKVKGYDIAAGTEVLINAWSIHRDPAIW 403 Query: 1380 GKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 G DA EF PER D + + + PFG G RIC G N A+ ++ L+ ++ RF + Sbjct: 404 GPDAEEFKPERHLDSTLDYHGQDLKYIPFGSGRRICPGINLAMGLVEVTLANLVGRFDWS 463 Query: 1560 LSP 1568 + P Sbjct: 464 VDP 466
>Q9V4I1:CP9B2_DROME Cytochrome P450 9b2 - Drosophila melanogaster (Fruit fly)| Length = 505 Score = 108 bits (269), Expect = 1e-22 Identities = 102/437 (23%), Positives = 191/437 (43%), Gaps = 23/437 (5%) Frame = +3 Query: 336 RVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRS--TRIGRLL 509 R L F ++H V F + TP + + DPEL++++ F HF + T RL Sbjct: 57 RQLTEFYERTRQHKLVGF-FNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLF 115 Query: 510 ANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPV----FSACCEEMITRWENSMSAQGLC 677 + L+ ++W R L P F K++ M + F+ C + + + + +G Sbjct: 116 NDMLSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGF- 174 Query: 678 EVDVCPEFQNLTGDVISRTAFG---SNFQEGMKIFQLQGE--LSERLIQAFQTLF---IP 833 EVD+ L+ D+I+ TAFG +++ F G+ + R +Q F+ + +P Sbjct: 175 EVDMKVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQFFKFMLSTLVP 234 Query: 834 GYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGK 1013 + +D R+++ + +++ I + ++ + Sbjct: 235 KLFSLLKLTIFDSAKVDYFARLVVEAMQYREKHNITRPDMIQL----------LMEAKNE 284 Query: 1014 ANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHY---FGRT 1184 + + ++I+ +C +F+FA E S L+ T L +P+ QE+ EE++ Sbjct: 285 SEDKWTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGA 344 Query: 1185 TPDFESLSRLKIVTMIFYEVLR---LYPPITFLTRRTYKAMELGGIK---YPAGVNLMLP 1346 ++++ ++ + M+ E LR L L + Y + G K + G + +P Sbjct: 345 PLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIP 404 Query: 1347 ILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMA 1526 I +H D D + + R+F+P+RF++ P + PFG GPR CIG +AL + K Sbjct: 405 ISGLHLD-DRYFPEPRKFDPDRFSEE-RKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGM 462 Query: 1527 LSTILQRFSFELSPSYI 1577 L +L + E SP I Sbjct: 463 LFNLLLHYKIEASPRTI 479
>Q964R0:CP6K1_BLAGE Cytochrome P450 6k1 - Blattella germanica (German cockroach)| Length = 524 Score = 108 bits (269), Expect = 1e-22 Identities = 100/418 (23%), Positives = 172/418 (41%), Gaps = 37/418 (8%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQRSTRI--GRLLANGLANHEGEKWAKHRRILNPAFH 581 P +++ DP +++ +L F F + ++ L + L G W R L+P F Sbjct: 85 PAILIKDPNIIKHVLVKDFNAFSDRHASAAESDTLGSQNLFTLNGAPWKYLRVKLSPTFT 144 Query: 582 HEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG------ 743 ++K+M P+ +C +++ + + + + ++V DVIS AFG Sbjct: 145 SGRMKKMYPLVESCAKQLQDYLKENCNTKA---IEVKETTAKYATDVISTCAFGIESNSL 201 Query: 744 ----SNFQE-GMKIFQLQGELSERLIQAFQTLFIPGY-------------------WFFP 851 + F+E G KIF+ R + F PG F+ Sbjct: 202 KDPNAEFREFGRKIFEF---TRYRTFEVMALFFSPGLVKFLNGNFFTKETTEFLRKVFWD 258 Query: 852 TKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLS 1031 T N R I R+ M L + K S++ + G Sbjct: 259 TINFRESNKISRDDFMDLLIQLKNKGTIDNEDGEVTEKVDKIDKDSHLFEFTG------- 311 Query: 1032 IEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTT--PDFESL 1205 ++++ + LF+ AG ET + L++TL LS+ P+ Q + R E+ + P +E + Sbjct: 312 -DNLVSQPALFFTAGFETNATTLSFTLYELSLQPDLQNRLRSEIAGVMKTSNGKPTYEDV 370 Query: 1206 SRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGG--IKYPAGVNLMLPILFIHHDPDIW 1379 + + M+ E LR YPP+ L R + ++ G + + + +L +H DP + Sbjct: 371 FGMPYLHMVVSETLRKYPPLPLLDRVCLQDYKVPGTDLIIERDTPVFIALLGLHRDPQYY 430 Query: 1380 GKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 R ++PERF++ N +R A + PFG GP CIG F K AL +L F Sbjct: 431 PNPER-YDPERFSE--ENKRQRKAYTYLPFGEGPHNCIGLRFGYMAVKTALVHMLAEF 485
>Q12586:CP52I_CANMA Cytochrome P450 52A9 - Candida maltosa (Yeast)| Length = 521 Score = 108 bits (269), Expect = 1e-22 Identities = 118/440 (26%), Positives = 186/440 (42%), Gaps = 33/440 (7%) Frame = +3 Query: 414 VMVPDPELVREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEK 590 ++ DPE ++ IL+ +F F +R LL G+ +GE W R +L P F E+ Sbjct: 99 LVTKDPENIKAILATQFEDFSLGKRLDFFKPLLGYGIFTLDGEGWKHSRAMLRPQFAREQ 158 Query: 591 I---KRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQ-- 755 + K + P F + + +I Q L F T D + FG + + Sbjct: 159 VGHVKLIEPHFQSLKKHIIKNKGQFFDIQEL--------FFRFTVDSATEFLFGESVESL 210 Query: 756 --EGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKE 929 E + Q + R + F F + T RAI + ++ G KK Sbjct: 211 KDESIGYDQQDFDFDGR--KNFAEAFNKAQEYLGT------RAILQLFYWLVNGADFKKS 262 Query: 930 RA-IKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIED-----IIQECKL-FYFAGMETT 1088 A + +++ +G L ++ ++++ L AG +TT Sbjct: 263 VAEVHKFTDYYVQKALDATPEELEKHSGYIFLYELVQQTRDPKVLRDQSLNILLAGRDTT 322 Query: 1089 SVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP------DFESLSRLKIVTMIFYEVLR 1250 + LL++ L L+ +PE + REE+ FG FESL + + + + E LR Sbjct: 323 AGLLSFALFELARNPEVWSRLREEIGDKFGLDEDATIEGISFESLKQCEYLKAVVNECLR 382 Query: 1251 LYP--PITFLTRRTYKAMELGG-------IKYPAGVNLMLPILFIHHDPDIWGKDAREFN 1403 +YP P F + + GG I G + I H DP +G DAR FN Sbjct: 383 MYPSVPRNFRIATKHTTLPRGGGPDGKDPIFIKKGAVVSYGINSTHLDPMYYGPDARLFN 442 Query: 1404 PERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF-SFELSPSYIH 1580 P+R++ K AF PF GGPRIC+GQ FAL EA L ++Q F EL+P+ ++ Sbjct: 443 PDRWSK--PETKKLGWAFLPFNGGPRICLGQQFALTEASYVLVRMIQNFKELELTPNTVY 500 Query: 1581 AP--YTVITLQPQHGAQIRL 1634 P T +T+ GA I++ Sbjct: 501 PPRRLTNLTMSLYDGAYIKV 520
>O44221:CP4E5_DROMT Cytochrome P450 4e5, mitochondrial precursor - Drosophila mettleri| (Fruit fly) Length = 522 Score = 107 bits (268), Expect = 1e-22 Identities = 106/431 (24%), Positives = 180/431 (41%), Gaps = 20/431 (4%) Frame = +3 Query: 339 VLPMFTNAIKEHGKVSFT-WFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN 515 +L F ++ K +F W G ++V +P+ + I+++ + L Sbjct: 54 ILNTFFEFWHKYNKDNFRIWIGYYANILVSNPKHLEVIMNSTTLIEKLDIYDMLHPWLGE 113 Query: 516 GLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCP 695 GL +G KW KHR+++ P FH ++ V + + I R + + + +D Sbjct: 114 GLLTSKGSKWHKHRKMITPTFHFNILQDFHQVMNENSAKFIKRLKEVSAGDNI--IDFQD 171 Query: 696 EFQNLTGDVISRTAFGSNFQ--------EGMKIFQLQGELSERLIQAFQTL--------F 827 E LT D I TA G + +K F+ + ++AF+ L F Sbjct: 172 ETHYLTLDAICDTAMGVTINAIEKRDTVDVVKAFKDMCHIIN--MRAFRPLQRSDFLYRF 229 Query: 828 IPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSN 1007 P Y + K + ++ +I I + I + A K + + Sbjct: 230 SPEYATY-AKTLKTLKDFTNDI--IAKRIKVHRTAAAKTNQEGSEFSRKKMLPDTLLSAT 286 Query: 1008 GKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTT 1187 L+ ++I +E F F G +TT+ + + +LS PE Q K EE G Sbjct: 287 IDGR-PLNQQEIYEEVSTFMFEGHDTTTSGVAFAGYILSRFPEEQRKLYEEQQAVMGNEL 345 Query: 1188 ---PDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFI 1358 F+ +S +K + + E R+YP + F+ R T K + G P G L L I+ + Sbjct: 346 NRDATFQEISAMKYLDLFIKEAQRVYPSVPFIGRYTDKDYNIHGTIMPKGTTLNLGIIVL 405 Query: 1359 HHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTI 1538 +D ++ ++ F PERF P + PF GPR CIGQ FAL E K +S + Sbjct: 406 GYDDRVF-EEPHRFYPERF----EKQKPGPFEYVPFSAGPRNCIGQKFALLELKTVISKL 460 Query: 1539 LQRFSFELSPS 1571 ++ +FE+ P+ Sbjct: 461 VR--TFEVLPA 469
>P11715:CP17A_RAT Cytochrome P450 17A1 - Rattus norvegicus (Rat)| Length = 507 Score = 107 bits (268), Expect = 1e-22 Identities = 110/448 (24%), Positives = 189/448 (42%), Gaps = 24/448 (5%) Frame = +3 Query: 294 RSQPMPP--GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSN 458 RS P P GS PR M N K ++G + G T V++ +L RE+L Sbjct: 29 RSLPSLPLVGSLPFLPRRGHMHVNFFKLQEKYGPIYSLRLGTTTTVIIGHYQLAREVLIK 88 Query: 459 KFGHFGKQRSTRIGRLLAN---GLANHE-GEKWAKHRRILNPAFH----HEKIKRML-PV 611 K F + LL++ G+A + G W HR+++ F +K+++++ Sbjct: 89 KGKEFSGRPQMVTQSLLSDQGKGVAFADAGSSWHLHRKLVFSTFSLFKDGQKLEKLICQE 148 Query: 612 FSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGEL 791 + C+ M+ + S+ P F ++T ++I F ++++ Sbjct: 149 AKSLCDMMLAHDKESIDLS-------TPIFMSVT-NIICAICFNISYEKNDPKLTAIKTF 200 Query: 792 SERLIQAFQTL----FIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXX 959 +E ++ A P FP K ++ + +L GI K + Sbjct: 201 TEGIVDATGDRNLVDIFPWLTIFPNKGLEVIKGYAKVRNEVLTGIFEKCREKFDSQSISS 260 Query: 960 XXXXXXXXXSNMQQSN---GKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMH 1130 N +N G+ S I+ + AG+ETT+ +L W L L + Sbjct: 261 LTDILIQAKMNSDNNNSCEGRDPDVFSDRHILATVGDIFGAGIETTTTVLKWILAFLVHN 320 Query: 1131 PEWQEKAREEVLHYFGRT-TPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMEL 1304 PE ++K ++E+ Y G + TP F S L ++ EVLR+ P L + + Sbjct: 321 PEVKKKIQKEIDQYVGFSRTPTFNDRSHLLMLEATIREVLRIRPVAPMLIPHKANVDSSI 380 Query: 1305 GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPR 1481 G P ++++ + +HHD + W + +F PERF D + P ++ PFG GPR Sbjct: 381 GEFTVPKDTHVVVNLWALHHDENEWDQPD-QFMPERFLDPTGSHLITPTQSYLPFGAGPR 439 Query: 1482 ICIGQNFALQEAKMALSTILQRFSFELS 1565 CIG+ A QE + + +LQRF ++S Sbjct: 440 SCIGEALARQELFVFTALLLQRFDLDVS 467
>P58048:C71B8_ARATH Cytochrome P450 71B8 - Arabidopsis thaliana (Mouse-ear cress)| Length = 506 Score = 107 bits (268), Expect = 1e-22 Identities = 102/461 (22%), Positives = 181/461 (39%), Gaps = 22/461 (4%) Frame = +3 Query: 246 LFTGDIPENSRFNAEARSQPMPPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVP 425 LF +P + P+ H + + F EHG V FG P V++ Sbjct: 19 LFKKLLPSKWKLPPGPTGLPIIGNLHQLGRLLHSSFHKLSLEHGPVMLLRFGVVPMVVIS 78 Query: 426 DPELVREILSNKFGHFGKQRSTRIGRLLANGLANHE---------GEKWAKHRRILN-PA 575 E +++L ++ + +L+ANGL GE W + ++++ Sbjct: 79 SKEAAKQVLKSR-----DLETCSRPKLVANGLFTRNFKDIAFAQYGEDWREMKKLVGLEL 133 Query: 576 FHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQ 755 F+ +K K + + ++ + S Q L VD+ F + T +I R +FG NF+ Sbjct: 134 FNPKKHKFFRYIREEEGDLLVKKLSKSSQTQTL--VDLRKAFFSFTAGIIFRVSFGQNFR 191 Query: 756 EGMKIFQLQGELSERLIQ---------AFQTLFIPGYWFFPTKNNRRMRAIDREIRMILR 908 E I + E L+Q AF F G + + + + I++ + + Sbjct: 192 ECDFIDM---DRLEELVQESETNVFSFAFTDFFPTGLGWLVDRISGQHSRIEKAFSKLTK 248 Query: 909 GIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETT 1088 + +K + +S + ++ + +I G+ Sbjct: 249 FFQHVIDEELKIGQSQDHSNLVSSMLDMINRSTEYGSFKITSDHLIAMMTDIVLGGVNAG 308 Query: 1089 SVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDF--ESLSRLKIVTMIFYEVLRLYPP 1262 ++ + WT+ L+ HP +K REE+ G E L +++ + ++ E RL+PP Sbjct: 309 TITMIWTMTELTRHPRVMKKLREEIRATLGPNKERITEEDLEKVEYLKLVIKETFRLHPP 368 Query: 1263 ITFLT-RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAA 1439 FL R+ +E+ G P ++ + I DP W + EFNPERFA+ N Sbjct: 369 GPFLLPRQVMSDIEIQGYHIPKNAHIKISTYAIGRDPKCW-TNPEEFNPERFANTSINYK 427 Query: 1440 KRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + PFG G R C G + ++ L IL F + L Sbjct: 428 GQHYELLPFGAGRRSCPGMTLGITILELGLLNILYYFDWSL 468
>Q9V3S0:CP4G1_DROME Cytochrome P450 4g1 - Drosophila melanogaster (Fruit fly)| Length = 556 Score = 107 bits (267), Expect = 2e-22 Identities = 117/483 (24%), Positives = 187/483 (38%), Gaps = 56/483 (11%) Frame = +3 Query: 270 NSRFNAEARSQPMPP-----GSHHIAP-----RVLPMFTNAIKEHGKVSFTWFGPTPRVM 419 NSR + P PP G H+A +L + + ++G+ W G V Sbjct: 47 NSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGLGYLNKYGETMKAWLGNVLLVF 106 Query: 420 VPDPELVREILSNKFGHFGKQRSTRIGR-LLANGLANHEGEKWAKHRRILNPAFHHEKIK 596 + +P + ILS H K R + +GL G W HR+++ P FH +K Sbjct: 107 LTNPSDIELILSGH-QHLTKAEEYRYFKPWFGDGLLISNGHHWRHHRKMIAPTFHQSILK 165 Query: 597 RMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG-SNFQEGMKIF 773 +P F + ++ R M + DV T D++ TA G EG K F Sbjct: 166 SFVPTFVDHSKAVVAR----MGLEAGKSFDVHDYMSQTTVDILLSTAMGVKKLPEGNKSF 221 Query: 774 QL--------------QGELSERL--IQAFQTL---------FIPGYWFFPTKNNRR--- 869 + Q +L RL I F L I G K+ + Sbjct: 222 EYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVKDRKENFQ 281 Query: 870 --MRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXX-----SNMQQSNGKANLGL 1028 RAI EI + K+ +++ M + ++ Sbjct: 282 EESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEW 341 Query: 1029 SIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP---DFE 1199 + +DI+ E F G +TTS ++ L ++ +H + Q K E FG F Sbjct: 342 NEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCTFA 401 Query: 1200 SLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKY--PAGVNLMLPILFIHHDPD 1373 +K + + E LRLYPP+ + RR ++L Y P G +++ +H PD Sbjct: 402 DTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPD 461 Query: 1374 IWGK----DAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTIL 1541 I+ D F PER A+ + +F PF GPR C+G+ +A+ + K+ LSTI+ Sbjct: 462 IYPNPTKFDPDNFLPERMAN------RHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIV 515 Query: 1542 QRF 1550 + + Sbjct: 516 RNY 518
>Q91Z85:CP17A_PERLE Cytochrome P450 17A1 - Peromyscus leucopus (White-footed mouse)| Length = 509 Score = 107 bits (266), Expect = 2e-22 Identities = 113/452 (25%), Positives = 199/452 (44%), Gaps = 29/452 (6%) Frame = +3 Query: 294 RSQPMPP--GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSN 458 RS P P GS PR M N K ++G + G P V++ +L RE+L Sbjct: 29 RSLPFLPLVGSLPFLPRHGHMHVNFFKLQEKYGPIYSLRLGTIPTVIIGQYQLAREVLIK 88 Query: 459 KFGHF-GKQRSTRIGRLLAN---GLANHEGEK-WAKHRRILNPAF--HHEKIKRMLPVF- 614 K F G+ + +G LL+N G+A + + W HR++ +F + +R+ + Sbjct: 89 KGKEFSGRPQMVTLG-LLSNQGKGIAFADSDDAWQLHRKLALSSFALFRDGDQRLETIIC 147 Query: 615 ---SACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQG 785 S+ C+ ++T E S+ P F ++T ++I F ++++ I Sbjct: 148 QEASSLCDLLLTHNEESVDLSQ-------PIFMSVT-NIICAICFSTSYENRDPILTTIQ 199 Query: 786 ELSERLIQAFQTL----FIPGYWFFPTKNNRRMRAIDREIRM---ILRGIIGKKERAIKN 944 +E ++ P FP N+ + I R +++ +L ++ K + N Sbjct: 200 TFTEGILNCLDNENLVDIFPWLTIFP---NKTLEKIKRHVKVRDEVLIDMLEKCKEKFNN 256 Query: 945 XXXXXXXXXXXXXXSNMQQSNGKANLG-LSIEDIIQECKLFYFAGMETTSVLLTWTLIVL 1121 N +N + G S I+ F+ AG+ETT+ +L W + L Sbjct: 257 DSISNLTDILIQAKMNADNNNTTDHQGSFSDSHILSTVGDFFGAGIETTTSVLCWIVAFL 316 Query: 1122 SMHPEWQEKAREEVLHYFGRT-TPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKA- 1295 +PE ++K ++E+ G + TP F + L ++ EVLR+ P L +KA Sbjct: 317 LHNPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLRIRPVAPMLI--PHKAN 374 Query: 1296 --MELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPF 1466 +G P ++++ + +HH+ W + R F PERF D + P+ ++ PF Sbjct: 375 IDSSIGEFTIPKDTHVVINLWALHHNEKEWDQPDR-FMPERFLDATGSHLITPSLSYLPF 433 Query: 1467 GGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 G GPR CIG+ A Q + ++ +LQRF ++ Sbjct: 434 GAGPRACIGEVLARQVLFLYVACLLQRFDLDV 465
>P16496:CP52C_CANMA Cytochrome P450 52A3 - Candida maltosa (Yeast)| Length = 523 Score = 106 bits (265), Expect = 3e-22 Identities = 110/433 (25%), Positives = 176/433 (40%), Gaps = 32/433 (7%) Frame = +3 Query: 414 VMVPDPELVREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEK 590 V DPE ++ +L+ +F F R LL +G+ +GE W R +L P F E+ Sbjct: 101 VFTVDPENIKAVLATQFNDFALGARHAHFDPLLGDGIFTLDGEGWKLSRAMLRPQFAREQ 160 Query: 591 I---KRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSN---- 749 I K + P +++ + Q L F T D + FG + Sbjct: 161 IAHVKALEPHVQILAKQIKLNKGKTFDLQEL--------FFRFTVDTATEFLFGESVHSL 212 Query: 750 FQEGMKI---FQLQGELSERLIQAFQT----LFIPGYW--FFPTKNNRRMRAIDREIRMI 902 + E + I + G E +AF T L Y F+ N + R + ++ + Sbjct: 213 YDEKLGIPAPNDIPGR--ENFAEAFNTSQHYLATRTYSQIFYWLTNPKEFRDCNAKVHKL 270 Query: 903 LRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGME 1082 + + A + ++Q+ L + +I+ AG + Sbjct: 271 AQYFVNTALNATEKEVEEKSKGGYVFLYELVKQTRDPKVLQDQLLNIM-------VAGRD 323 Query: 1083 TTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP------DFESLSRLKIVTMIFYEV 1244 TT+ LL++ + L+ +P+ K REEV FG FE+L + + + + E Sbjct: 324 TTAGLLSFAMFELARNPKIWNKLREEVEVNFGLGDEARVDEISFETLKKCEYLKAVLNET 383 Query: 1245 LRLYP--PITFLTRRTYKAMELGGIK-------YPAGVNLMLPILFIHHDPDIWGKDARE 1397 LR+YP PI F T + GG K P G +++ + H +G+DA E Sbjct: 384 LRMYPSVPINFRTATRDTTLPRGGGKDGNSPIFVPKGSSVVYSVYKTHRLKQFYGEDAYE 443 Query: 1398 FNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYI 1577 F PER+ + + K A+ PF GGPRIC+GQ FAL EA ++ + Q F S Sbjct: 444 FRPERWFE--PSTRKLGWAYLPFNGGPRICLGQQFALTEASYVIARLAQMFEHLESKDET 501 Query: 1578 HAPYTVITLQPQH 1616 + P I L H Sbjct: 502 YPPNKCIHLTMNH 514
>P70687:CP17A_MESAU Cytochrome P450 17A1 - Mesocricetus auratus (Golden hamster)| Length = 511 Score = 106 bits (265), Expect = 3e-22 Identities = 108/456 (23%), Positives = 198/456 (43%), Gaps = 23/456 (5%) Frame = +3 Query: 264 PENSRFNAEARSQPMPPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVR 443 P++ F S P P H P V F +++G + G T V++ +L + Sbjct: 28 PKSLPFLPLVGSLPFIPRHGH--PHV--NFFKLQEKYGPIYSLRLGSTTTVIIGQYQLAK 83 Query: 444 EILSNKFGHF-GKQRSTRIGRLLANGLA---NHEGEKWAKHRRILNPAFH-----HEKIK 596 E+L K F G+ +G L G G W HR++ +F ++K++ Sbjct: 84 EVLVKKGKEFSGRPHMVTLGLLSDQGKGIAFADSGGSWQLHRKLALSSFALFRDGNQKLE 143 Query: 597 RML-PVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIF 773 +++ S+ C+ ++T E S+ P F ++T ++I FG +++ I Sbjct: 144 KIICQKASSLCDFLLTHNEESIDLSE-------PIFNSIT-NIICIICFGISYENRDPIL 195 Query: 774 QLQGELSERLIQAFQTLFI----PGYWFFPTKNNRRMRAIDREIRM---ILRGIIGKKER 932 +E ++ + + P FP N+ + I + +++ +L GI+ K + Sbjct: 196 ATIKSFTEGILNSLGNDHLVDIFPWLTIFP---NKTVDMIKKNVKIRDEVLSGILEKCKE 252 Query: 933 AIKNXXXXXXXXXXXXXXSNMQQSN---GKANLGLSIEDIIQECKLFYFAGMETTSVLLT 1103 + +N +N G+ + S I+ + AG+ETT+ +L+ Sbjct: 253 KFNSDSISSLMDLLIQAKTNADNNNTSEGQGSNAFSDMHILATIADIFGAGIETTASVLS 312 Query: 1104 WTLIVLSMHPEWQEKAREEVLHYFGRT-TPDFESLSRLKIVTMIFYEVLRLYPPITFLT- 1277 W + L +PE ++K ++E+ G + TP F + L ++ EVLR+ P L Sbjct: 313 WIIAFLLHNPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLRIRPVAPMLIP 372 Query: 1278 RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-A 1454 R M +G P +++ + +HH W + R F PERF D + P+ + Sbjct: 373 HRANSDMSIGEFSIPKFTPVIINLWALHHSEKEWDQPDR-FMPERFLDPTGSHLITPSLS 431 Query: 1455 FFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + PFG G R CIG+ A QE + ++ +LQRF ++ Sbjct: 432 YLPFGAGARSCIGEVLARQELFLFMAHLLQRFDLDV 467
>Q9VVN6:CP312_DROME Probable cytochrome P450 312a1 - Drosophila melanogaster (Fruit fly)| Length = 510 Score = 106 bits (264), Expect = 4e-22 Identities = 110/460 (23%), Positives = 189/460 (41%), Gaps = 31/460 (6%) Frame = +3 Query: 273 SRFNAEARSQPMPP-----GSHHI-----APRVLPMFTNAIKEH--GKVSFTWFGPTPRV 416 SR + P PP G HI P L T I EH + W G + Sbjct: 25 SRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRRATEMINEHLHDHRAKLWMGTKLYL 84 Query: 417 MVPDPELVREILSNKFGHFGKQRSTRI-GRLLANGLANHEGEKWAKHRRILNPAFHHEKI 593 + +P+ ++ + S + K R+ L GL EKW+ R+I+ PAF++ I Sbjct: 85 VDCNPKDIQALCSAQ-QLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRKIVMPAFNYTMI 143 Query: 594 KRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNF--QEGMK 767 K+ + VF ++T + A+ ++D T D I TA G + Q K Sbjct: 144 KQFVAVFEKQSRILLTNV--AKFAESGDQIDFLQLISCFTLDTICETALGVSVGSQSSAK 201 Query: 768 IFQLQGELSERLI--QAFQTLFIPGYWFFP-TKNNRRMRAIDREIRMILRGIIGKKERAI 938 L S +I + + +F + F T + +R + + + + GII K+ I Sbjct: 202 SEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFTEGIIQKRIDEI 261 Query: 939 KNXXXXXXXXXXXXXXSNMQQ----------SNGKANLGLSIEDIIQECKLFYFAGMETT 1088 +++ S G L+++DI +E F G + T Sbjct: 262 NQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLT 321 Query: 1089 SVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD---FESLSRLKIVTMIFYEVLRLYP 1259 + L + + +++HPE Q++ REEV G+ + E + +L+ + E LR+YP Sbjct: 322 ATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYP 381 Query: 1260 PITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAA 1439 R+ + P G ++++ +++ D + D F P+R+A G + Sbjct: 382 SGPLTARKATANCTINDFFIPKGSDVIISPIYMGRCKDFF-PDPMVFKPDRWAIG-AEPK 439 Query: 1440 KRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 F PF G R C+GQ +A+ KM L+ +L+ F FE Sbjct: 440 IEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFE 479
>O65438:C71AR_ARATH Cytochrome P450 71A27 - Arabidopsis thaliana (Mouse-ear cress)| Length = 499 Score = 106 bits (264), Expect = 4e-22 Identities = 104/437 (23%), Positives = 181/437 (41%), Gaps = 17/437 (3%) Frame = +3 Query: 303 PMPPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQ 482 P+ H + P + +G + FG P ++V P++ +I+ F + Sbjct: 41 PVIGNLHQLGPNPHRYLHSLSLRYGPLMLLHFGRVPVLVVSCPDVTNDIMKTHDLKFANR 100 Query: 483 RSTRIGRLLANG----LANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEE----MI 638 ++ + G + GE W + + H +M+ F EE M Sbjct: 101 PKSKAINIFMEGGRDIIFGPYGEDWKSMKSL---GVVHLLNNKMVRSFENLREEEIKVMT 157 Query: 639 TRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQE---GMKIFQLQGELSERLIQ 809 + E + S+ V++ LT D+I R G + E G+ I L SE + Sbjct: 158 EKLEEASSSSS--SVNLSKLLMTLTNDIICRITLGRKYNEEEGGIDIKNLVMTSSEFFGK 215 Query: 810 AFQTLFIPGY-WF-FPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXX 983 F FIP W + + + +M+ I+ ++ L ++ + A Sbjct: 216 FFFGDFIPSLAWIDWISGIDDKMKDINNKLDCFLDSMVQEHVDADHKEPSDFIDMLL--- 272 Query: 984 XSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV 1163 + Q + D+I K +F+G TT+ L WT+ L HPE +K ++E+ Sbjct: 273 ---LIQKDKTKRFKFDRSDLILILKDMFFSGTATTASQLEWTMTELMRHPECMKKLQDEI 329 Query: 1164 ----LHYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGV 1331 H T + E ++ L V E LRL+P L R + ++L G AG Sbjct: 330 NSFSTHNLNVTEKEVEKMNYLHCVIK---EGLRLHPSGPLLFRLPSEDVQLKGYDISAGT 386 Query: 1332 NLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQ 1511 ++++ + +P IWG DA E+ PER + + F PFG G R+C G F+L Sbjct: 387 HVIINAWALQRNPAIWGLDANEYRPERHFWYEFGFQRTDSKFVPFGAGRRLCPGIGFSLV 446 Query: 1512 EAKMALSTILQRFSFEL 1562 +K+AL+ +++RF++ L Sbjct: 447 LSKLALANLVKRFNWRL 463
>Q9V776:CP317_DROME Probable cytochrome P450 317a1 - Drosophila melanogaster (Fruit fly)| Length = 518 Score = 105 bits (263), Expect = 5e-22 Identities = 94/404 (23%), Positives = 180/404 (44%), Gaps = 18/404 (4%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQR--STRIGRLLANGLANHEGEKWAKHRRILNPAFH 581 PR ++ D EL+R+I+ F +F + + L+ L GE W + R+ L+P+ Sbjct: 87 PRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPLSGDLYALRGESWKEMRQKLDPSLE 146 Query: 582 HEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEG 761 +++ + E+++ +++ +Q V + + +++ FG N ++ Sbjct: 147 GDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRRYVLSSLAKCVFGLNAEQ- 205 Query: 762 MKIFQLQG--ELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRM-------ILRGI 914 K + L+ +++E + + + ++ N RM + R + +L I Sbjct: 206 RKTYPLEDFEQMTELALNSHKHGYLMNLMMIRFPNFCRMLRMRRTPKQAEEYFIKLLTSI 265 Query: 915 IGKKERAIKNXXXXXXXXXXXXXXSNMQ-QSNGKANLGLSIE-DIIQECKLFYFAGMETT 1088 + ++E + K + Q LG ++ ++ +F AG E T Sbjct: 266 VEQRETSGKPQKDYLQLLIDVKALEFITYQYEADKELGAHLQNELAAHADVFLKAGYEQT 325 Query: 1089 SVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDF--ESLSRLKIVTMIFYEVLRLYPP 1262 + L++ L L++HPE Q + REEV R E + L + + E LR++P Sbjct: 326 ANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVINETLRMHPI 385 Query: 1263 ITFLTRRT---YKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISN 1433 ++ RRT Y + + L++P IHHDPDI+ D EF P+R++ G + Sbjct: 386 TPYILRRTLNDYAVPDHPKYILVKELFLIIPTHAIHHDPDIY-PDPEEFKPDRWS-GPRD 443 Query: 1434 AAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELS 1565 + + +F FG G R CIG FA + ++AL+ +L + F L+ Sbjct: 444 SLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSLN 487
>O65788:C71B2_ARATH Cytochrome P450 71B2 - Arabidopsis thaliana (Mouse-ear cress)| Length = 502 Score = 105 bits (263), Expect = 5e-22 Identities = 107/463 (23%), Positives = 192/463 (41%), Gaps = 31/463 (6%) Frame = +3 Query: 267 ENSRFNA--EARSQPMPPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELV 440 + S+FN S P+ HH+A F ++G + F G P V++ E Sbjct: 25 KTSKFNLPPSPSSLPIIGNLHHLAGLPHRCFHKLSIKYGPLVFLRLGSVPVVVISSSEAA 84 Query: 441 REIL-SNKFGHFGKQRSTRIGRLLANGLANHE----GEKWAKHRRI-LNPAFHHEKIKRM 602 +L +N + ++ G+L + G + GE W + R++ + F +K++ Sbjct: 85 EAVLKTNDLECCSRPKTVGSGKL-SYGFKDITFAPYGEYWREVRKLAVIELFSSKKVQSF 143 Query: 603 LPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQ 782 + + ++ + S Q VD+ F +LT +I R A G NF E + Q Sbjct: 144 RYIREEEVDFVVKKVSESALKQS--PVDLSKTFFSLTASIICRVALGQNFNESGFVID-Q 200 Query: 783 GELSERLIQAFQTL-------FIPGY------WFFPTKNNRRMRAIDREIRMILRGII-- 917 + E + ++ + L F PG W F + ++++ + +E+ + +I Sbjct: 201 DRIEELVTESAEALGTFTFSDFFPGGLGRFVDWLF--QRHKKINKVFKELDAFYQHVIDD 258 Query: 918 -----GKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGME 1082 G+K + I + N KA I+ + + AG++ Sbjct: 259 HLKPEGRKNQDIVTLILDMIDKQEDSDSFKLNMDNLKA--------IVMDV---FLAGID 307 Query: 1083 TTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDF--ESLSRLKIVTMIFYEVLRLY 1256 T++V + W + L +P +KA+E + G E L +++ + I E RL+ Sbjct: 308 TSAVTMIWAMTELIRNPRVMKKAQESIRTTLGLKKERITEEDLGKVEYLNHILKETFRLH 367 Query: 1257 PPITFLT-RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISN 1433 P + F+ R T +++ G P + L + I DP W D EFNPERFA+ + Sbjct: 368 PALPFVVPRETMSHIKIQGYDIPPKTQIQLNVWTIGRDPKRWN-DPEEFNPERFANSSVD 426 Query: 1434 AAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + PFG G RIC G A+ ++AL +L F + + Sbjct: 427 FRGQHFDLLPFGSGRRICPGMPMAIASVELALMNLLYYFDWSM 469
>Q9V674:CP6G1_DROME Cytochrome P450 6g1 - Drosophila melanogaster (Fruit fly)| Length = 524 Score = 105 bits (262), Expect = 6e-22 Identities = 99/406 (24%), Positives = 174/406 (42%), Gaps = 24/406 (5%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQ--RSTRIGRLLA-NGLANHEGEKWAKHRRILNPAF 578 P +++ D EL++ IL F F + R G L N L W R L P F Sbjct: 82 PGLIIRDIELIKSILIKDFNRFHNRYARCDPHGDPLGYNNLFFVRDAHWKGIRTKLTPVF 141 Query: 579 HHEKIKRMLPVFSACCEEM---ITRWENSMSAQGLCEV-DVCPEFQNLTGDVISRTAFG- 743 K+K+M + +++ + R S + E+ ++C +F D I+ AFG Sbjct: 142 TSGKVKQMYTLMQEIGKDLELALQRRGEKNSGSFITEIKEICAQFST---DSIATIAFGI 198 Query: 744 --SNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGII 917 ++ + F+ G A F ++ + R++ + +R I Sbjct: 199 RANSLENPNAEFRNYGRKMFTFTVARAKDFFVAFFLPKLVSLMRIQFFTADFSHFMRSTI 258 Query: 918 GK--KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTS 1091 G +ER K + + + ++ + +F+ AG ET+S Sbjct: 259 GHVMEERERSGLLRNDLIDVLVSLRKEAAAEPSKPHYAKNQDFLVAQAGVFFTAGFETSS 318 Query: 1092 VLLTWTLIVLSMHPEWQEKAREEVLHYF--GRTTPDFESLSRLKIVTMIFYEVLRLYPPI 1265 +++ L ++ HPE Q++ R+E+ G + +E + L+ + M+ EVLR+YP + Sbjct: 319 STMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEVLRMYPVL 378 Query: 1266 TFLTRRTYKAME---------LGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFA 1418 FL R Y+++E G + +PI +HHDP W + +F+PERF+ Sbjct: 379 PFLDRE-YESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYW-TNPSQFDPERFS 436 Query: 1419 DGISNAAKRPA-AFFPFGGGPRICIGQNFALQEAKMALSTILQRFS 1553 +N A A+ PFG GP CIG L ++K+ L ++L+ S Sbjct: 437 P--ANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHS 480
>P13527:CP6A1_MUSDO Cytochrome P450 6A1 - Musca domestica (House fly)| Length = 509 Score = 105 bits (262), Expect = 6e-22 Identities = 102/407 (25%), Positives = 169/407 (41%), Gaps = 19/407 (4%) Frame = +3 Query: 393 WFGPTPRVMVPDPELVREILSNKFGHFGKQRS--TRIGRLLANGLANHEGEKWAKHRRIL 566 + G P +V D EL + +L F +F + L L EGEKW R L Sbjct: 76 FLGHKPAAVVLDKELRKRVLIKDFSNFANRGLYYNEKDDPLTGHLVMVEGEKWRSLRTKL 135 Query: 567 NPAFHHEKIKRM----LPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRT 734 +P F K+K M L V E M + E S E+D+ DVI Sbjct: 136 SPTFTAGKMKYMYNTVLEVGQRLLEVMYEKLEVSS------ELDMRDILARFNTDVIGSV 189 Query: 735 AFG---SNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRR-MRAIDREIRMI 902 AFG ++ + F G S + L + FP + + MR + ++ Sbjct: 190 AFGIECNSLRNPHDRFLAMGRKSIE-VPRHNALIMAFIDSFPELSRKLGMRVLPEDVHQF 248 Query: 903 LRGIIGKK-ERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGM 1079 I + + KN N +S K GL+ ++ + +F+ G Sbjct: 249 FMSSIKETVDYREKNNIRRNDFLDLVLDLKNNPESISKLG-GLTFNELAAQVFVFFLGGF 307 Query: 1080 ETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD---FESLSRLKIVTMIFYEVLR 1250 ET+S + + L L+ + + Q++ REEV F + D +++L + + + E LR Sbjct: 308 ETSSSTMGFALYELAQNQQLQDRLREEVNEVFDQFKEDNISYDALMNIPYLDQVLNETLR 367 Query: 1251 LYP-----PITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 YP +T T Y P G + +P+L IH+DP+++ + EF+PERF Sbjct: 368 KYPVGVGSALTRQTLNDYVVPHNPKYVLPKGTLVFIPVLGIHYDPELY-PNPEEFDPERF 426 Query: 1416 ADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 + + + + FG GPR CIG F ++++ L+ +++ F F Sbjct: 427 SPEMVKQ-RDSVDWLGFGDGPRNCIGMRFGKMQSRLGLALVIRHFRF 472
>P58045:C71AE_ARATH Cytochrome P450 71A14 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 105 bits (262), Expect = 6e-22 Identities = 98/413 (23%), Positives = 174/413 (42%), Gaps = 16/413 (3%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANG----LANHEGE 539 +G + FG P ++V ++ +++ + ++ + NG + + GE Sbjct: 64 YGPLMLLHFGRVPVLVVSSSDVAHDLMKTHDLKVANRPQLKVVEKIFNGGREMVFSPYGE 123 Query: 540 KWAKHRRI-LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTG 716 W + + + + + +K++ V EM+ R E + S +++ LT Sbjct: 124 YWRQIKSVCIVNLLNKKKVQSFEKVREEEISEMMERVEKASSDSS--PLNLSELLLTLTS 181 Query: 717 DVISRTAFGSNF--QEGMKIFQLQGELSERLIQAFQT-LFIPGYWFFPTKNNRRMRAIDR 887 DV SR + G + +E M F++Q L+ F +IP + ++R +D Sbjct: 182 DVTSRVSLGRKYSKEESMSDFKIQMRKITELVGGFPVGEYIPCLAWID-----KLRGVDE 236 Query: 888 EIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIE--DIIQECKL 1061 + + + E+ ++ + + N G+ I DI Sbjct: 237 KAEEVSKAFGDLMEKVLQEHLDATDKPTLDFVDVLLSLERHERN-GVQIRRSDIKFLILD 295 Query: 1062 FYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-----TTPDFESLSRLKIVT 1226 + AG ETT LL W + L HPE +K ++E+ + + D E + LK V Sbjct: 296 MFLAGTETTYALLEWIMTELIRHPECMKKLQDEIRAKATKLILYISEEDVEDMKYLKAVV 355 Query: 1227 MIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFN 1403 EVLRL+PP+ L R + ++L G AG +++ I D WG DA EF Sbjct: 356 K---EVLRLHPPLPLLVPRELSEDIKLKGYDIAAGTQVIINAWAIQRDTMTWGIDAEEFR 412 Query: 1404 PERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 PER D + + F PFG G RIC G FA+ ++ L+ ++ RF++ + Sbjct: 413 PERHLDSLVDFRGTNFEFIPFGSGRRICPGIGFAMALVEVTLANLVNRFNWRM 465
>Q9GQM9:CP6L1_BLAGE Cytochrome P450 6l1 - Blattella germanica (German cockroach)| Length = 503 Score = 105 bits (261), Expect = 8e-22 Identities = 105/450 (23%), Positives = 186/450 (41%), Gaps = 31/450 (6%) Frame = +3 Query: 315 GSHHIAPRVL--------------PMFTNAIKE----HGKVSFTWFGPTPRVMVPDPELV 440 G HH+AP+ L +F + E H + F FG P ++V DP L+ Sbjct: 33 GVHHVAPQPLVGSMLRLLTFSVSPAVFIQGVHEAAGSHPYIGFYIFG-RPALLVRDPSLL 91 Query: 441 REILSNKFGHFGKQRSTRIGRLLANGLANH---EGEKWAKHRRILNPAFHHEKIK----R 599 + IL F +F + ++ G AN +G +W + R + F ++K R Sbjct: 92 QHILVKDFSNFTDRLTSSNKHKDPVGAANLFCIKGNRWRQIRACITHTFSTARLKIMFSR 151 Query: 600 MLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQL 779 +L S + ++ R ++ + L + + S T + S Q ++ Sbjct: 152 VLNSASVTRDYILERGNQPINVKDLFVRTSLDSMCSTLFGIESSTLYNSEAQFLHYGHKM 211 Query: 780 QGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXX 959 R ++A F P + + I I +++ + Sbjct: 212 MRWTPYRALEALAHFFSPELLNVFDTRLFECESTEFLINAFSEAITEREKTGL------- 264 Query: 960 XXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEW 1139 S +Q K + +S +++ + LF+ AG ETTS + + + L++HPE Sbjct: 265 --YCSDLVDSLIQLK--KQLIDVSEHEVLGQAMLFFAAGFETTSSAMAFAMYELALHPEI 320 Query: 1140 QEKAREEVLH----YFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELG 1307 Q++ R E+ + G+ T +E + ++ + M+ EVLR YPP++F+ R + Sbjct: 321 QDRLRTEIQEVTACHGGQVT--YEGVKKMSYLDMVVSEVLRKYPPMSFIDRVCLHDYHIP 378 Query: 1308 G--IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPR 1481 G + G + + +L +H D I+ D +FNPERF + + P ++ PFG GPR Sbjct: 379 GTDVVIEKGTPIFVSLLGLHRD-SIFYPDPEDFNPERF-NKEKKSGVHPFSYIPFGDGPR 436 Query: 1482 ICIGQNFALQEAKMALSTILQRFSFELSPS 1571 CIG L K+ + +LQ E S Sbjct: 437 NCIGLRLGLMSVKLVIIMLLQSLRVETHES 466
>P10615:CP52A_CANTR Cytochrome P450 52A1 - Candida tropicalis (Yeast)| Length = 543 Score = 104 bits (260), Expect = 1e-21 Identities = 120/448 (26%), Positives = 184/448 (41%), Gaps = 39/448 (8%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHH 584 P + DPE V+ IL+ +F F R + LL +G+ +G W R +L P F Sbjct: 116 PLIETKDPENVKAILATQFNDFSLGTRHDFLYSLLGDGIFTLDGAGWKHSRTMLRPQFAR 175 Query: 585 EKI---KRMLPVFSACCEEMITRWENSMSAQGL---CEVDVCPEF------QNLTGDVIS 728 E++ K + P + + + Q L VD EF ++L + + Sbjct: 176 EQVSHVKLLEPHMQVLFKHIRKHHGQTFDIQELFFRLTVDSATEFLLGESAESLRDESVG 235 Query: 729 RTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAI-----DREI 893 T +F +G F S+ QA++ L YW R+ AI D + Sbjct: 236 LTPTTKDF-DGRNEFADAFNYSQTN-QAYRFLLQQMYWILNGSEFRKSIAIVHKFADHYV 293 Query: 894 RMILRGI---IGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLF 1064 + L + KKE + +Q+ L + +I+ Sbjct: 294 QKALELTDEDLEKKEGYV-------------FLFELAKQTRDPKVLRDQLLNIL------ 334 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP------DFESLSRLKIVT 1226 AG +TT+ LL++ LS +PE K REE+ + FG FE+L + + Sbjct: 335 -VAGRDTTAGLLSFLFFELSRNPEIFAKLREEIENKFGLGQDARVEEISFETLKSCEYLK 393 Query: 1227 MIFYEVLRLYP--PITFLTRRTYKAMELGG-------IKYPAGVNLMLPILFIHHDPDIW 1379 + E LR+YP P F + GG I G +M IL H D DI+ Sbjct: 394 AVINETLRIYPSVPHNFRVATRNTTLPRGGGEGGLSPIAIKKGQVVMYTILATHRDKDIY 453 Query: 1380 GKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF-SF 1556 G+DA F PER+ + K A+ PF GGPRIC+GQ FAL EA +LQ F + Sbjct: 454 GEDAYVFRPERWFE--PETRKLGWAYVPFNGGPRICLGQQFALTEASYVTVRLLQEFGNL 511 Query: 1557 ELSPSYIHAP--YTVITLQPQHGAQIRL 1634 + P+ + P +TL GA++++ Sbjct: 512 KQDPNTEYPPKLQNTLTLSLFEGAEVQM 539
>Q9T0K0:C71AJ_ARATH Cytochrome P450 71A19 - Arabidopsis thaliana (Mouse-ear cress)| Length = 490 Score = 104 bits (260), Expect = 1e-21 Identities = 103/421 (24%), Positives = 178/421 (42%), Gaps = 24/421 (5%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTR-IGRLLANG----LANHEG 536 +G + FG TP ++V ++ +IL + T+ I ++L G A + G Sbjct: 64 YGPLMLLHFGRTPVLIVSSADVAHDILKTYDVICANRPKTKVIDKILRGGRDVAFAPY-G 122 Query: 537 EKWAKHRRI-LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLT 713 E W + + I + ++ ++ + + MI + EN+ S V++ F LT Sbjct: 123 EYWKQMKSICIQNLLSNKMVRSYKKIREDEIKLMIEKVENASSCSPPSPVNLSQLFMTLT 182 Query: 714 GDVISRTAFGSNF---QEGMKIFQLQGELSERLIQAFQTL--------FIPGY-WFFPTK 857 D+I R A G + ++G+ + E +++AF L +IP W + Sbjct: 183 NDIICRAALGRKYSSKEDGIDV--------ENIVRAFSALVGEFPIGEYIPSLSWIDKIR 234 Query: 858 N-NRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSI 1034 + +M +D+ L ++ + E A K+ + + K+ L L I Sbjct: 235 GQDHKMEEVDKRFDEFLERVVKEHEDANKDTRSDLVDTL-------LTIQSDKSALKLII 287 Query: 1035 EDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR----TTPDFES 1202 D+ + AG T+ L W + L +P+ +K +EE+ + T + E Sbjct: 288 WDM-------FLAGTATSLSFLEWAMTELMRNPKVMKKLQEEIRSSSRQGLFVTEKEAEK 340 Query: 1203 LSRLKIVTMIFYEVLRLYPPITFLTRRTYKA-MELGGIKYPAGVNLMLPILFIHHDPDIW 1379 + L+ V E LRL PP + R + + L G PAG +++ I D W Sbjct: 341 MDYLQAVIK---EALRLRPPAPLMVPRVFSEDVTLKGYNIPAGTQVIINAWAIQRDTTTW 397 Query: 1380 GKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 G DA EF PER D I + + F PFG G RIC G F + L+ I++RF++ Sbjct: 398 GIDAEEFRPERHLDSILDFQGQDFKFIPFGSGKRICPGIGFTSALIGVTLANIVKRFNWR 457 Query: 1560 L 1562 + Sbjct: 458 M 458
>Q964Q7:CP6D3_MUSDO Cytochrome P450 6d3 - Musca domestica (House fly)| Length = 520 Score = 103 bits (257), Expect = 2e-21 Identities = 112/447 (25%), Positives = 184/447 (41%), Gaps = 36/447 (8%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHF---GKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAF 578 P +++ D EL R+IL++ F F G + + AN A EG+ W R L P+F Sbjct: 75 PALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFAL-EGQSWRTLRMKLTPSF 133 Query: 579 HHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQE 758 K+K M +++ N + +D+ D+I FG Sbjct: 134 SSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDS 193 Query: 759 GMKIFQLQGELSERL-----------IQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMIL 905 LS+R +Q P T+ + + R ++ Sbjct: 194 FTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVK 253 Query: 906 RGIIGKKERAI--KNXXXXXXXXXXXXXXS-------NMQQSNGKANLGLSIEDIIQECK 1058 R I ++E + K+ S N +S +SI+ I Sbjct: 254 RTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSF 313 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV--------LHYFGRTTPDFESLSRL 1214 LFY AG ETT+ ++T+ L+M+PE +KA+ EV + GR T +E++ + Sbjct: 314 LFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRIT--YEAIQDM 371 Query: 1215 KIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPA--GVNLMLPILFIHHDPDIWGKD 1388 K + + E R YP + FL R+ + ++ K+ N+++ +L +H D + + Sbjct: 372 KYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYF-PE 430 Query: 1389 AREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSP 1568 + PERFAD + AA+ PFG GPR CI Q + K+AL+ IL F+ E P Sbjct: 431 PLAYKPERFADETKDYDA--AAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMP 488 Query: 1569 SYIHAPY---TVITLQPQHGAQIRLKK 1640 + A + T L P +G ++ L K Sbjct: 489 -HKEAEFQFNTAPVLVPVNGLRVGLSK 514
>P21595:CP56_YEAST Cytochrome P450-DIT2 - Saccharomyces cerevisiae (Baker's yeast)| Length = 489 Score = 103 bits (257), Expect = 2e-21 Identities = 104/421 (24%), Positives = 184/421 (43%), Gaps = 16/421 (3%) Frame = +3 Query: 360 AIKEHGKVSFTWFGPTPRVMVPDPELVREILSNK--FGHFGKQRSTRIGRLLA---NGLA 524 +++++G V F +FG ++V E + +I ++ F G Q+ L A + + Sbjct: 62 SMEKYGAVKF-FFGSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAYTGDNVI 120 Query: 525 NHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQ 704 + G W +R + H P+F + + T +N + +G + + P Q Sbjct: 121 SAYGAVWRNYRNAVTNGLQHFDDA---PIFKNA-KILCTLIKNRL-LEGQTSIPMGPLSQ 175 Query: 705 NLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAID 884 + D IS+ A G +F + + E LI+ + +F P + FP + + + Sbjct: 176 RMALDNISQVALGFDFGA---LTHEKNAFHEHLIRIKKQIFHPFFLTFPFLDVLPIPSRK 232 Query: 885 REIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKA--NLGLSIEDIIQECK 1058 + + ++ +E +K + +A N + + + Sbjct: 233 KAFK----DVVSFRELLVKRVQDELVNNYKFEQTTFAASDLIRAHNNEIIDYKQLTDNIV 288 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHP-EWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIF 1235 + AG E +L +L +L+ + EWQEK R+EV G T P + L+ L ++ Sbjct: 289 IILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVN---GITDP--KGLADLPLLNAFL 343 Query: 1236 YEVLRLYPPI-TFLTRRTYKAMELGG-IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPE 1409 +EV+R+YPP+ T + R T K +LG I P GV + HDP WG A +F PE Sbjct: 344 FEVVRMYPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPE 403 Query: 1410 RFADGIS------NAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPS 1571 R+ I AK A F GG R C+G+ AL E +++L+ +L++F + L P Sbjct: 404 RWGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPE 463 Query: 1572 Y 1574 + Sbjct: 464 W 464
>Q95328:CP17A_HORSE Cytochrome P450 17A1 - Equus caballus (Horse)| Length = 508 Score = 103 bits (257), Expect = 2e-21 Identities = 101/422 (23%), Positives = 183/422 (43%), Gaps = 23/422 (5%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANG-----LANH 530 K++G + G VMV +L +E+L K F + +L++ A+H Sbjct: 58 KKYGPIYSLRMGTKTTVMVGHYQLAKEVLIKKGKEFSGRPQVATLNILSDNQKGVAFADH 117 Query: 531 EGEKWAKHRRILNPAFH-----HEKIKRML-PVFSACCEEMITRWENSMSAQGLCEVDVC 692 G W HR+++ AF ++K+++++ S C+ + T+ ++ Sbjct: 118 -GAPWQLHRKLVRAAFALFKDGNQKLEKIICHETSLLCDLLATQNGQTIDLSS------- 169 Query: 693 PEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQ----TLFIPGYWFFPTKN 860 P F +T +VI F S++ +G + + +++ + P FP K+ Sbjct: 170 PLFLAVT-NVICWICFNSSYMKGDPALETMQNYHKGILETLEKDNVVDIFPALKIFPNKS 228 Query: 861 NRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLG---LS 1031 +MR +L I K + + N +N + LS Sbjct: 229 LEKMRHCVNIRNELLSKIFEKHKENFNSDSITSMLDLLIQAKKNSDNNNTGPDQDSKLLS 288 Query: 1032 IEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRT-TPDFESLS 1208 + I+ + AG+ETT+ ++ W + L P+ ++K +EE+ G + TP + Sbjct: 289 DKHILATIGDIFGAGVETTTSVVKWIVAFLLHDPQLKKKIQEEIDQNVGFSRTPTLSDRN 348 Query: 1209 RLKIVTMIFYEVLRLYPPITFLTRRTYKAM---ELGGIKYPAGVNLMLPILFIHHDPDIW 1379 RL ++ EVLR+ P L +KA+ +G G N+++ + +HH+ W Sbjct: 349 RLLLLEATIREVLRIRPVAPMLI--PHKALVDSSIGEFAVDDGTNVIINLWALHHNEKEW 406 Query: 1380 GKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 + R F PERF D + P+ ++ PFG GPR CIG+ A QE + + +LQRF+ Sbjct: 407 HQPDR-FMPERFLDPTGSQLISPSLSYLPFGAGPRSCIGELLARQELFLFTAWLLQRFNL 465 Query: 1557 EL 1562 E+ Sbjct: 466 EV 467
>P12394:CP17A_CHICK Cytochrome P450 17A1 - Gallus gallus (Chicken)| Length = 508 Score = 103 bits (257), Expect = 2e-21 Identities = 104/419 (24%), Positives = 174/419 (41%), Gaps = 23/419 (5%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANG-----LANHEG 536 +G + W G V+V + RE+L K F + T LL+ G A++ G Sbjct: 65 YGSLYGLWMGSHYVVVVNSYQHAREVLLKKGKAFAGRPRTVTTDLLSRGGKDIAFASY-G 123 Query: 537 EKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCE---------VDV 689 W R++++ A M S E++I R A LCE +D+ Sbjct: 124 PLWKFQRKLVHAALS------MFGEGSVALEKIICR-----EAASLCETLGAAQDMALDM 172 Query: 690 CPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQ--AFQTL--FIPGYWFFPTK 857 PE +V+ F S+++ G F+ E S+ ++ A ++L P FP + Sbjct: 173 APELTRAVTNVVCSLCFNSSYRRGDPEFEAMLEYSQGIVDTVAKESLVDIFPWLQIFPNR 232 Query: 858 NNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIE 1037 + ++ + +L+ + + A N + +N GL + Sbjct: 233 DLALLKRCLKVRDQLLQQKFTEHKEAFCGDTVRDLMDALLQVRLNAE-NNSPLEPGLELT 291 Query: 1038 D--IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTT-PDFESLS 1208 D ++ + AG+ETT+ +L W ++ L +PE Q+K +EE+ G P Sbjct: 292 DDHLLMTVGDIFGAGVETTTTVLKWAVLYLLHYPEVQKKIQEEMDQKIGLARHPHLSDRP 351 Query: 1209 RLKIVTMIFYEVLRLYPPITFLTRRTYKA-MELGGIKYPAGVNLMLPILFIHHDPDIWGK 1385 L + E LR+ P L A +G P G +++ + +HHD W K Sbjct: 352 LLPYLEATISEGLRIRPVSPLLIPHVSLADTSIGEYSIPKGARVVINLWSVHHDEKEWDK 411 Query: 1386 DAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 EFNP RF D P+ ++ PFG G R+C+G+ A E + L+ +LQRF+ E Sbjct: 412 P-EEFNPGRFLDEQGQHIHSPSPSYLPFGAGIRVCLGEVLAKMELFLFLAWVLQRFTLE 469
>Q9VRB3:CP6V1_DROME Probable cytochrome P450 6v1 - Drosophila melanogaster (Fruit fly)| Length = 520 Score = 102 bits (255), Expect = 4e-21 Identities = 109/428 (25%), Positives = 182/428 (42%), Gaps = 43/428 (10%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQ------RSTRIGRLLANGLANHEGEKWAKHRRILN 569 P +++ D +LVR +L F F + RS ++G L L + +W + R L Sbjct: 83 PALLIRDLQLVRTVLVEDFVSFSNRFAKCDGRSDKMGAL---SLFLAKQPEWREIRTRLA 139 Query: 570 PAFHHEKIKRMLPVFSAC-CE-----EMITRWENSMSAQGLCEV---DVCPEFQNLTGDV 722 PAF K+K+M + C+ + +TR A+ V DVC + D+ Sbjct: 140 PAFAGAKLKQMFSLMEEIGCDLEWYLKRLTRDLRRGDAERGAIVSIKDVCDLYNT---DM 196 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSE--------------RLIQAFQTLFIPGYWFFPTKN 860 I+ AFG ++ + L+ SE R+I F ++P P Sbjct: 197 IASIAFG------LRSYSLRNTQSEIGSHCQDLFRPNVRRIIDLFVIFYLPK--LVPLLR 248 Query: 861 NRRMRAIDRE-IRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIE 1037 + E +R +++ +I ++ER +++QQ K++ + Sbjct: 249 PKLFTEPHAEFLRRVIQLVIEERERGGDLRNDLIEMLLTLKKEADLQQD--KSHFTHHRD 306 Query: 1038 DIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-----GRTTPDFES 1202 + + F AG+ET S +++ L L+ P Q + R E+ F GR T +E+ Sbjct: 307 FLAAQAASFEVAGIETCSASMSFALYELAKQPLMQSRLRREIREAFASNPNGRLT--YEA 364 Query: 1203 LSRLKIVTMIFYEVLRLYPPITFLTR--------RTYKAMELGGIKYPAGVNLMLPILFI 1358 ++R++ + M+ E LR YP + L R R Y G+ + + L I Sbjct: 365 VARMEFLDMVVEETLRKYPIVPLLERECTPINKKRFYSLRPHAECYTRRGMPVFISNLAI 424 Query: 1359 HHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTI 1538 HHDP W D F+PERF+ + A + P ++ PFG GPR CIG L + K+ L Sbjct: 425 HHDPKYW-PDPDRFDPERFS-AANKALQAPMSYMPFGAGPRNCIGMQIGLLQIKLGLVYF 482 Query: 1539 LQRFSFEL 1562 L + E+ Sbjct: 483 LHQHRVEI 490
>Q9CX98:CP2U1_MOUSE Cytochrome P450 2U1 - Mus musculus (Mouse)| Length = 530 Score = 102 bits (255), Expect = 4e-21 Identities = 90/359 (25%), Positives = 146/359 (40%), Gaps = 14/359 (3%) Frame = +3 Query: 528 HEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQN 707 H G W + RR + H + + L + EE E +M G P N Sbjct: 155 HYGPIWKQQRRFSHSTLRHFGLGK-LSLEPRIIEEFAYVKE-AMQKHGEAPFSPFPIISN 212 Query: 708 LTGDVISRTAFGSNFQEGMKIFQLQGELSERLI------QAFQTLFIPGYWFFPTKNNRR 869 ++I FG F K F+ + R + Q F P +++ P + Sbjct: 213 AVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINICPWFYYLPFGPFKE 272 Query: 870 MRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQ 1049 +R I+R+I L+ II + + ++ +M++ G + ED Sbjct: 273 LRQIERDISCFLKNIIREHQESLDASNPQDFIDMYLL---HMEEEQGASRRSSFDEDY-- 327 Query: 1050 ECKLFYF------AGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG-RTTPDFESLS 1208 LFY AG +TT+ L W L+ +S++P+ Q+K EE+ G P + Sbjct: 328 ---LFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQKKVHEEIERVIGCDRAPSLTDKA 384 Query: 1209 RLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGK 1385 ++ EV RL + + T + L G P G +++ + +H DP IW K Sbjct: 385 QMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGFTIPKGTVVLINLWSVHRDPAIWEK 444 Query: 1386 DAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 +F P RF D KR F PFG G R+C+G+ A E + +++Q F+F L Sbjct: 445 -PDDFCPHRFLDDQGQLLKR-ETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQTFTFAL 501
>P51590:CP2J3_RAT Cytochrome P450 2J3 - Rattus norvegicus (Rat)| Length = 502 Score = 102 bits (255), Expect = 4e-21 Identities = 91/409 (22%), Positives = 167/409 (40%), Gaps = 10/409 (2%) Frame = +3 Query: 363 IKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLL--ANGLANHEG 536 +K++G V F P V+V L++EI + +F + T + + L NGL G Sbjct: 72 VKKYGNVLSLDFANIPSVVVTGMPLIKEIFTQMEHNFLNRPVTLLRKHLFNKNGLIFSSG 131 Query: 537 EKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTG 716 + W + RR + + + +E ++ +G D Sbjct: 132 QTWKEQRRFALMTLRNFGLGKKS--LEQRIQEEAYHLVEAIKDEGGLPFDPHFNINKAVS 189 Query: 717 DVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPT------KNNRRMRA 878 ++I FG F+ FQ L + + ++ Y FP +++ + + Sbjct: 190 NIICSVTFGERFEYHDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRILQYLPGSHQTLFS 249 Query: 879 IDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECK 1058 R++++ + II R + M + K + E++I Sbjct: 250 NWRKLKLFISDIIKNHRR---DWDPDEPRDFIDAFLKEMAKYPDKTTTSFNEENLICSTL 306 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIF 1235 +FAG ETTS L W L+ ++++PE QEK + E+ G+ P+ + + Sbjct: 307 DLFFAGTETTSTTLRWALLCMALYPEVQEKMQAEIDRVIGQGRQPNLADRDSMPYTNAVI 366 Query: 1236 YEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 +EV R+ I F + R L G P G ++ + +H DP W FNPE Sbjct: 367 HEVQRIGNIIPFNVPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWA-TPDTFNPEH 425 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 F + + K+ +F PF G R C+G+ A E + +++++Q+F+F+ Sbjct: 426 FLE--NGQFKKRESFLPFSMGKRACLGEQLARSELFIFITSLIQKFTFK 472
>Q6EIG3:CP26B_DANRE Cytochrome P450 26B1 - Danio rerio (Zebrafish) (Brachydanio rerio)| Length = 511 Score = 102 bits (255), Expect = 4e-21 Identities = 107/435 (24%), Positives = 179/435 (41%), Gaps = 13/435 (2%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFG----HFGKQRSTRIGRLLANGLANHE 533 +++G V T P + V E VR++L + + + ST +G N LAN Sbjct: 78 QKYGNVFKTHLLGRPLIRVTGAENVRKVLMGEHSLVTVDWPQSTSTLLG---PNSLANSI 134 Query: 534 GEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLT 713 G+ K R+I F HE ++ LP +E + W ++ ++V E Q L+ Sbjct: 135 GDIHRKRRKIFAKVFSHEALESYLPKIQQVIQETLRVWSSNPDP-----INVYRESQRLS 189 Query: 714 GDVISRTAFGSNFQEGMK--IFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDR 887 ++ R G E +F E E + L GY + +RA D Sbjct: 190 FNMAVRVLLGFRIPEEEMHCLFSTFQEFVENVFSLPIDLPFSGY-------RKGIRARDS 242 Query: 888 EIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFY 1067 + I E+AI+ + +S + N L+++++ + Sbjct: 243 LQKSI--------EKAIREKPLHTQGKDYTDALDVLLESAKENNTELTMQELKESTIELI 294 Query: 1068 FAGMETTSVLLTWTLIVLSMHPEWQEKAREEV-----LH--YFGRTTPDFESLSRLKIVT 1226 FA TT+ T ++ L HP EK REE+ LH + +S+ LK + Sbjct: 295 FAAFATTASASTSLVMQLLRHPAVLEKLREELRSCGLLHDGCLCQGELRLDSIISLKYLD 354 Query: 1227 MIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNP 1406 + EVLRL+ P++ R + EL G++ P G ++M I H ++ KD F+P Sbjct: 355 CVIKEVLRLFAPVSGGYRIATQTFELDGVQVPKGWSVMYSIRDTHDTSAVF-KDVEAFDP 413 Query: 1407 ERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAP 1586 +RF+ S + + PFGGG R C+G+ A K+ + FELS Sbjct: 414 DRFSPERSEDREGRFHYLPFGGGVRSCLGKQLATLFLKLLAVELAGGSRFELSTRTFPRM 473 Query: 1587 YTVITLQPQHGAQIR 1631 +V + P G +++ Sbjct: 474 ISVPVVHPTDGLRVK 488
>Q9Y8G7:C505_FUSOX Bifunctional P-450:NADPH-P450 reductase - Fusarium oxysporum| Length = 1066 Score = 102 bits (255), Expect = 4e-21 Identities = 117/467 (25%), Positives = 196/467 (41%), Gaps = 23/467 (4%) Frame = +3 Query: 285 AEARSQPMPPGSHHIAPRVLPMFTNAIKEHGKVSFTW-------FGPTPRVMVPDPELVR 443 AE+ P PPG + + + +N + + +++ T+ G + V L+ Sbjct: 2 AESVPIPEPPG-YPLIGNLGEFTSNPLSDLNRLADTYGPIFRLRLGAKAPIFVSSNSLIN 60 Query: 444 EILSNK-FGHFGKQRSTRIGRLLANGL--ANHEGEKWAKHRRILNPAFHHEKIKRMLPVF 614 E+ K F K +++ + +GL A + W K RIL PAF I+ M P Sbjct: 61 EVCDEKRFKKTLKSVLSQVREGVHDGLFTAFEDEPNWGKAHRILVPAFGPLSIRGMFPEM 120 Query: 615 SACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTA----FGSNFQEGMKIF-QL 779 ++ ++ +D F L D ++ A F S ++E + F + Sbjct: 121 HDIATQLCMKFARHGPRT---PIDTSDNFTRLALDTLALCAMDFRFYSYYKEELHPFIEA 177 Query: 780 QGE-LSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIR--MILRGIIGKKERAIKNXX 950 G+ L+E + + F P + + RA + + + L + + A + Sbjct: 178 MGDFLTESGNRNRRPPFAPNFLY---------RAANEKFYGDIALMKSVADEVVAARKAS 228 Query: 951 XXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMH 1130 + + G+ LS E+I + F AG ETTS L++ + L + Sbjct: 229 PSDRKDLLAAMLNGVDPQTGEK---LSDENITNQLITFLIAGHETTSGTLSFAMYQLLKN 285 Query: 1131 PEWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGG 1310 PE K ++EV GR E L++L ++ + E LRL PIT LGG Sbjct: 286 PEAYSKVQKEVDEVVGRGPVLVEHLTKLPYISAVLRETLRLNSPITAFGLEAIDDTFLGG 345 Query: 1311 IKYPAGVNLMLPILFI--HHDPDIWGKDAREFNPERFADGISNAAKR--PAAFFPFGGGP 1478 KY ++ L H DP ++G DA +F PER D + P + PFG G Sbjct: 346 -KYLVKKGEIVTALLSRGHVDPVVYGNDADKFIPERMLDDEFARLNKEYPNCWKPFGNGK 404 Query: 1479 RICIGQNFALQEAKMALSTILQRFSFELS-PSYIHAPYTVITLQPQH 1616 R CIG+ FA QE+ +A+ + Q F+F ++ P+Y +T++P H Sbjct: 405 RACIGRPFAWQESLLAMVVLFQNFNFTMTDPNYALEIKQTLTIKPDH 451
>Q9V4I0:CP9B1_DROME Cytochrome P450 9b1 - Drosophila melanogaster (Fruit fly)| Length = 505 Score = 102 bits (254), Expect = 5e-21 Identities = 97/410 (23%), Positives = 178/410 (43%), Gaps = 22/410 (5%) Frame = +3 Query: 405 TPRVMVPDPELVREILSNKFGHFGKQRSTRIG--RLLANGLANHEGEKWAKHRRILNPAF 578 TP + + DP+L+++I F HF ++ I RL+ + L + W R +L P F Sbjct: 79 TPMIQINDPQLIKKICVKDFDHFPNHQTLNIPNERLVNDMLNVMRDQHWRNMRSVLTPVF 138 Query: 579 HHEKIKRMLPVFS---ACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG-- 743 K++ M + + A C E + + + + E+D+ L+ DVI+ TAFG Sbjct: 139 TSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKVLCNKLSNDVIATTAFGLK 198 Query: 744 -SNFQEGMKIFQLQGE---LSERL--IQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMIL 905 ++F + F G+ S L ++ L P + F ++ +R+++ Sbjct: 199 VNSFDDPENEFHTIGKTLAFSRGLPFLKFMMCLLAPKVFNFFKLTIFDSTNVEYFVRLVV 258 Query: 906 RGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMET 1085 + +++ I + ++ ++ + ++I+ +C +F+FA E Sbjct: 259 DAMQYREKHNITRPDMIQL----------LMEAKKESKDNWTDDEIVAQCFIFFFAAFEN 308 Query: 1086 TSVLLTWTLIVLSMHPEWQEKAREEVLHY---FGRTTPDFESLSRLKIVTMIFYEVLR-- 1250 S L+ T L + + QE+ EEV +++ + + M+ E LR Sbjct: 309 NSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAPLTYDAAQEMTYMDMVISESLRKW 368 Query: 1251 -LYPPITFLTRRTYKAMELGGIK---YPAGVNLMLPILFIHHDPDIWGKDAREFNPERFA 1418 L L + Y + G K + AG N+ +PI +H D + + R F+PERF+ Sbjct: 369 TLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQR-FDPERFS 427 Query: 1419 DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSP 1568 + P + PFG GPR CIG +A+ +AK L ++ + E SP Sbjct: 428 ERRKKDLI-PYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKIEASP 476
>Q64410:CP17A_CAVPO Cytochrome P450 17A1 - Cavia porcellus (Guinea pig)| Length = 508 Score = 102 bits (254), Expect = 5e-21 Identities = 114/497 (22%), Positives = 200/497 (40%), Gaps = 33/497 (6%) Frame = +3 Query: 219 QGIGGTRYRLFTGDIPENSRFNAEARSQPMPPGSHHIAPRVLPMFTNAIKEHGKVSFTWF 398 QG GT+Y +P S P P S H+ F K++G + Sbjct: 20 QGSSGTKYPKSLPSLPV-------VGSLPFLPKSGHMHVN----FFKLQKKYGPIYSFRL 68 Query: 399 GPTPRVMVPDPELVREILSNKFGHF-GKQRSTRIGRLLANGLA---NHEGEKWAKHRRIL 566 G T V++ +L RE+L K F G+ +T + L NG W HRR++ Sbjct: 69 GSTTTVVIGHHQLARELLIKKGKEFSGRPLTTTVALLSDNGKGIAFADSSATWQLHRRLV 128 Query: 567 NPAFH-----HEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISR 731 +F +K++ ++ C+E+ + + G + D+ ++I Sbjct: 129 LSSFSLFRDGEQKLENII------CQELSALCDFLATCDGQVK-DLSSSIFMTVVNIICM 181 Query: 732 TAFGSNFQEGMKIFQLQGELSERLIQAFQTLFI------------PGYWFFPTKNNRRMR 875 F +++EG ++ I+ F T F+ P FP K +R Sbjct: 182 ICFSVSYKEG--------DMELVTIRRFTTGFVNSLSDDNLVDIFPWLKIFPNKTLEMIR 233 Query: 876 AIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGK----ANLGLSIEDI 1043 +L I+ + + ++ N +N +NL S + I Sbjct: 234 KYTEIRGAMLSKILKECKEKFRSDSVSNLIDLLIQAKVNENNNNSSLDQDSNL-FSDKHI 292 Query: 1044 IQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRT-TPDFESLSRLKI 1220 + + AG+ET+S ++ W + L +P+ ++K +EE+ H G + TP F + L + Sbjct: 293 LTTLGDIFGAGVETSSSVVLWVIAFLLHNPQVKKKIQEEIDHNVGFSRTPTFSDRNHLLM 352 Query: 1221 VTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDARE 1397 + EVLR+ P L + +G N+++ + +HH+ W + + Sbjct: 353 LEATIREVLRIRPVAPILIPHKANTDSSIGEFAIDKDTNVLVNLWALHHNEQEWDRPD-Q 411 Query: 1398 FNPERFADGISNAAKRPAA-FFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELS--- 1565 F PERF D + P++ + PFG GPR C+G+ A QE + + +LQ+F E+ Sbjct: 412 FMPERFLDPTGSQIIVPSSSYLPFGAGPRSCVGEALARQEIFLITAWLLQKFDLEVPEGG 471 Query: 1566 --PSYIHAPYTVITLQP 1610 PS P V + P Sbjct: 472 QLPSLEGIPKIVFLIDP 488
>Q27902:CP6B4_PAPGL Cytochrome P450 6B4 - Papilio glaucus (Tiger swallowtail butterfly)| Length = 500 Score = 102 bits (253), Expect = 7e-21 Identities = 98/423 (23%), Positives = 172/423 (40%), Gaps = 36/423 (8%) Frame = +3 Query: 405 TPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHH 584 TP +++ D ++++ ++ F F + L + + +G++W R+ P F Sbjct: 77 TPCLLLRDLDVIKHVMIKDFDLFNDRGVEFSEEGLGLNIFHADGDRWRVLRQCFTPLFTS 136 Query: 585 EKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGM 764 K+K ML + S ++ I E + E + P + T I+ AFG E Sbjct: 137 GKLKNMLNLMSDRGDKFIKMVEKFCDKEP--EQQIIPLVRKFTMASITTCAFGMELDE-- 192 Query: 765 KIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKN 944 E+ E L + +F Y EI M+ GI+ K +I + Sbjct: 193 -------EMIETLDKLDSLIFTTSY--------------GNEIDMMYPGILKKLNSSIFS 231 Query: 945 XXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECK---------------------- 1058 ++Q GK + D+I E + Sbjct: 232 KMIAPFFDNLTKTI--IEQRGGKPTNRKDLMDLILELRQKKAIEPMKKTHDEQVTTLELT 289 Query: 1059 ---------LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD--FESL 1205 +FY AG ET++ +++ L L+ +P+ QEK EV R + +++L Sbjct: 290 DSVIAAQTFIFYAAGYETSASTMSFLLFELAENPDIQEKVIAEVDETLKRHNGEITYDTL 349 Query: 1206 SRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGG--IKYPAGVNLMLPILFIHHDPDIW 1379 S + +T +F+E LR YP L R + G + G +++ IH+DP + Sbjct: 350 SEMTYLTQVFHETLRKYPVADILLRNAKADYAVPGTNVTLKKGQTVVVSGFGIHYDPKYY 409 Query: 1380 GKDAREFNPERFA-DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 D +F+PERF+ + + N + P A+ PFG G R C+G F + ++ + +L +F F Sbjct: 410 -PDPEKFDPERFSPENVRN--RHPCAYIPFGAGQRKCLGMRFGQWQVQVCIIKLLSKFRF 466 Query: 1557 ELS 1565 E S Sbjct: 467 EPS 469
>P30437:CP17A_ONCMY Cytochrome P450 17A1 - Oncorhynchus mykiss (Rainbow trout) (Salmo| gairdneri) Length = 514 Score = 102 bits (253), Expect = 7e-21 Identities = 107/437 (24%), Positives = 183/437 (41%), Gaps = 24/437 (5%) Frame = +3 Query: 330 APRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF-GKQRSTRIGRL 506 AP VL F +++G GP ++V + +E+L K F G+ R+ L Sbjct: 54 APHVL--FQKLQQKYGHTYSLMMGPHTVILVNHHQHAKEVLLKKGKIFAGRPRTVTTDLL 111 Query: 507 LANG----LANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWE----NSMS 662 +G A++ G W HR+ ++ A M SA E++I R +++ Sbjct: 112 TRDGKDIAFADY-GATWRFHRKTVHGALC------MFGEGSASIEKIICREALSLCDTLR 164 Query: 663 AQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQ--AFQTL--FI 830 G +D+ PE +V+ F S++ G F+ + S+ ++ A +L Sbjct: 165 ESGSASLDLSPELTRAVTNVVCSLCFSSSYCRGDPEFEAMLQFSQGIVDTVAKDSLVDIF 224 Query: 831 PGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNG 1010 P FP + R ++ + I ++ KK K+ ++S Sbjct: 225 PWLQVFPNADLRLLK----QCVSIRDKLLQKKYEEHKSDYSDHEQRDLLDALLRAKRSAE 280 Query: 1011 KAN--------LGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVL 1166 N +GLS + ++ + AG+ETTS +L W + L HP+ Q++ +EE+ Sbjct: 281 NNNTAEITMETVGLSEDHLLMTVGDIFGAGVETTSTVLKWAIAYLIHHPQVQQRIQEELD 340 Query: 1167 HYFGRT-TPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKA-MELGGIKYPAGVNLM 1340 G TP L + EVLR+ P L + +G G ++ Sbjct: 341 SVVGGDRTPQLSDRGSLPYLEATIREVLRIRPVAPLLIPHVAQTDTSIGKFTVRKGARII 400 Query: 1341 LPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFALQEA 1517 + + +HHD W K+ F+P RF + P+ ++ PFG G R+C+G+ A E Sbjct: 401 INLWSLHHDEKEW-KNPEMFDPGRFLNEEGTGLCIPSPSYLPFGAGVRVCLGEALAKMEI 459 Query: 1518 KMALSTILQRFSFELSP 1568 + LS ILQR + +SP Sbjct: 460 FLFLSWILQRLTMTVSP 476
>P93530:C71D6_SOLCH Cytochrome P450 71D6 - Solanum chacoense (Chaco potato)| Length = 501 Score = 101 bits (252), Expect = 9e-21 Identities = 108/456 (23%), Positives = 189/456 (41%), Gaps = 27/456 (5%) Frame = +3 Query: 276 RFNAEARSQPMPPGS---------HHIAP-RVLPMFTNAIKEHGKVSFTWFGPTPRVMVP 425 +++ ++++ +PPG HH+A R + + K++G + G V+V Sbjct: 21 KYSKNSQTKKLPPGPWKLPFIGSMHHLAGGRPHRVLRDLAKKYGPLMHLQLGEVSAVVVT 80 Query: 426 DPELVREILSNKFGHFGKQRSTRIGRLLANGLANHE---------GEKWAKHRRILNPAF 578 P++ +E+L F + +LLA + ++ GE W + R+I Sbjct: 81 SPDMAKEVLKTHDIAFASRP-----KLLAMDIICYDRCDIAFSPYGEYWKQMRKICVTEV 135 Query: 579 HHEKIKRMLPVFSACCEEMITRWENSMSAQGLCE-VDVCPEFQNLTGDVISRTAFGSNFQ 755 K R S C+E++ ++ S+ E V+ T + R+AFG + Sbjct: 136 LSAKSVRSFS--SIRCDEVVRLIDSIQSSSSSGELVNFKERVIWFTSSMTCRSAFGQLPK 193 Query: 756 EGMKIFQLQGELSERLIQAFQTLFI-PGYWFFPT--KNNRRMRAIDREIRMILRGIIGKK 926 E +L E+ RL + F I P Y F + R++ + R++ I+ +I + Sbjct: 194 EQDMFIKLIREVI-RLAEGFDVADIFPSYKFLHVFGRAKRKLLNVHRKVDAIVEDVINEH 252 Query: 927 ERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIE-DIIQECKLFYFA-GMETTSVLL 1100 ++ + + +L I D I+ + FA G ET+S Sbjct: 253 KKNFATRKNDDHALGGENLIDVLLKLMNDKSLQFPINNDNIKAIIIDMFAAGTETSSTTT 312 Query: 1101 TWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLT 1277 W ++ + +P KA+ EV F + T D + LK + ++ E +RL+ PI L Sbjct: 313 VWAMVEMLKNPRVLAKAQAEVREAFRNKVTFDENDVEDLKYLKLVIKETMRLHAPIPLLV 372 Query: 1278 -RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAA 1454 R K E+ G P +M+ + + DP W D F PERF + Sbjct: 373 PRECRKETEINGYTIPVKTKVMVNVWALGRDPKYWD-DVECFKPERFEQCSIDFIGNNFE 431 Query: 1455 FFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + PFGGG RIC G +F L + L+ +L F ++L Sbjct: 432 YLPFGGGRRICPGTSFGLANDYLPLAQLLCHFDWKL 467
>Q9VMS7:C4AC3_DROME Probable cytochrome P450 4ac3 - Drosophila melanogaster (Fruit fly)| Length = 509 Score = 101 bits (252), Expect = 9e-21 Identities = 92/364 (25%), Positives = 154/364 (42%), Gaps = 16/364 (4%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 L +GL +KW R+ L PAFH ++ L +F ++ I + ++ + L Sbjct: 127 LGDGLLISIDQKWHTRRKTLTPAFHFNILQSFLSIFKEESKKFIKILDKNVGFE-LELNQ 185 Query: 687 VCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIP---------GY 839 + P+F T + I TA G + +G + I F+ +F + Sbjct: 186 IIPQF---TLNNICETALGVKLDD-----MSEGNEYRKAIHDFEIVFNQRMCNPLMFFNW 237 Query: 840 WFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQS--NGK 1013 +FF + ++ I R I GII +K + K M + + Sbjct: 238 YFFLFGDYKKYSRILRTIHGFSSGIIQRKRQQFKQKQLGQVDEFGKKQRYAMLDTLLAAE 297 Query: 1014 ANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD 1193 A + + I E F F G +TTS L +TL++L++H + QE+ EE+ D Sbjct: 298 AEGKIDHQGICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQDL----PED 353 Query: 1194 FESLSRLKIVTMIFYEV-----LRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFI 1358 + +S + +I E LRL+P + R + + G+ P + + I I Sbjct: 354 IDEVSMFQFNELIHLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDI 413 Query: 1359 HHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTI 1538 D + K +F PERF ++ + P AF PF GPR CIGQ F + E K+ L+ + Sbjct: 414 MRDARHFPKP-NQFLPERFLPE-NSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAV 471 Query: 1539 LQRF 1550 ++ F Sbjct: 472 IRNF 475
>Q9V675:CP6G2_DROME Probable cytochrome P450 6g2 - Drosophila melanogaster (Fruit fly)| Length = 519 Score = 101 bits (251), Expect = 1e-20 Identities = 105/445 (23%), Positives = 192/445 (43%), Gaps = 36/445 (8%) Frame = +3 Query: 408 PRVMVPDPELVREILSNKFGHFGKQRSTRIGR---LLANGLANHEGEKWAKHRRILNPAF 578 P +++ DPE+VR IL F F + S+ + L + + + W + R L+P F Sbjct: 81 PALLLRDPEMVRNILVKDFAGFSNRYSSSDPKGDPLGSQNIFFLKNPAWKEVRLKLSPFF 140 Query: 579 HHEKIKRMLPVFSACCEEMITRWENS------MSAQGLCEVDVCPEFQNLTGDVISRTAF 740 ++K+M P+ + M L ++C + T DVI+ A+ Sbjct: 141 TGNRLKQMFPLIEEVGASLDAHLRQQPLHNERMRCFDLEAKELCALY---TTDVIATVAY 197 Query: 741 G---SNFQEGMKIFQLQGE--LSERLIQAFQ---TLFIPGYWFFPTKNNRRMRAIDREIR 896 G ++F + F+ G L++A + F+P F R + + E Sbjct: 198 GVSANSFTDPKCEFRRHGRSVFEFNLLRAAEFTLVFFLPHLVPFV-----RFKVVPAEAT 252 Query: 897 MILRG----IIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNG-KANLGLSIEDIIQECKL 1061 LR ++ ++E++ + + + +++G K + ++ + L Sbjct: 253 RFLRKTINYVMSEREKSGQKRNDLIDILIEFRRSTQLAKASGIKDQFVFEGDILVAQAVL 312 Query: 1062 FYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV----LHYFGRTTPDFESLSRLKIVTM 1229 F+ AG E++S + + + L+ + Q++ REE+ + G+ T + + L+ + M Sbjct: 313 FFTAGFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVESGGQVT--LKMIESLEFMQM 370 Query: 1230 IFYEVLRLYPPITFLTRRTYKAMELGGIKY------PAGVNLMLPILFIHHDPDIWGKDA 1391 I EVLR+YPP+ FL R + + P G+ + +P +H DP + + Sbjct: 371 ILLEVLRMYPPLPFLDRECTSGRDYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQP- 429 Query: 1392 REFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPS 1571 R+F PERF+ + P + PFG GP CIG+ F +AK+ L +L+ S Sbjct: 430 RKFLPERFSPE-NRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSER 488 Query: 1572 YIHA----PYTVITLQPQHGAQIRL 1634 H P +IT Q + G +RL Sbjct: 489 TPHRMQLDPKAIIT-QAKGGIHLRL 512
>Q95036:CP6B5_PAPGL Cytochrome P450 6B5 - Papilio glaucus (Tiger swallowtail butterfly)| Length = 476 Score = 101 bits (251), Expect = 1e-20 Identities = 97/423 (22%), Positives = 172/423 (40%), Gaps = 36/423 (8%) Frame = +3 Query: 405 TPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHH 584 TP +++ D ++++ ++ F F + L + + +G++W R+ P F Sbjct: 77 TPCLLLRDLDVIKHVMIKDFDLFNDRGVEFSEEGLGLNIFHADGDRWRVLRQCFTPLFTS 136 Query: 585 EKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGM 764 K+K ML + S ++ I E + E + P + T I+ AFG E Sbjct: 137 GKLKNMLNLMSDRGDKFIKMVEKICDKEP--EQQIIPLVRKFTMASITTCAFGMELDE-- 192 Query: 765 KIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKN 944 E+ E L + +F Y EI M+ GI+ K ++ + Sbjct: 193 -------EMIETLDKLDSLIFTTSY--------------GNEIDMMYPGILKKLNSSLFS 231 Query: 945 XXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECK---------------------- 1058 ++Q GK + D+I E + Sbjct: 232 KMIAPFFDNLTKTI--IEQRGGKPTNRKDLMDLILELRQKKAIEPMKKTHDEQVTTLELT 289 Query: 1059 ---------LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD--FESL 1205 +FY AG ET++ +++ L L+ +P+ QEK EV R + +++L Sbjct: 290 DSVIAAQTFIFYAAGYETSASTMSFLLFELAENPDIQEKVIAEVDETLKRHNGEITYDTL 349 Query: 1206 SRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGG--IKYPAGVNLMLPILFIHHDPDIW 1379 S + +T +F+E LR YP L R + G + G +++ IH+DP + Sbjct: 350 SEMTYLTQVFHETLRKYPVADILLRNAKADYAVPGTNVTLKKGQTVVVSGFGIHYDPKYY 409 Query: 1380 GKDAREFNPERFA-DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 D +F+PERF+ + + N + P A+ PFG G R C+G F + ++ + +L +F F Sbjct: 410 -PDPEKFDPERFSPENVRN--RHPCAYIPFGAGQRKCLGMRFGQWQVQVCIIKLLSKFRF 466 Query: 1557 ELS 1565 E S Sbjct: 467 EPS 469
>P30608:CP52F_CANTR Cytochrome P450 52A6 - Candida tropicalis (Yeast)| Length = 524 Score = 101 bits (251), Expect = 1e-20 Identities = 104/418 (24%), Positives = 167/418 (39%), Gaps = 33/418 (7%) Frame = +3 Query: 432 ELVREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKI---KR 599 E ++ +L+ +F F R LL +G+ +GE W R +L P F ++I K Sbjct: 108 ENIKAVLATQFTDFSLGTRHAHFYPLLGDGIFTLDGEGWKHSRAMLRPQFARDQIGHVKA 167 Query: 600 MLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSN----FQEGMK 767 + P +++ + Q L F T D + FG + + E + Sbjct: 168 LEPHIQILAKQIKLNKGKTFDIQEL--------FFRFTVDTATEFLFGESVHSLYDEKLG 219 Query: 768 IFQLQGELSERLIQAFQTLFIPGYWFFPTK----------NNRRMRAIDREIRMILRGII 917 I E+ R F T F + T+ N + R + ++ + + + Sbjct: 220 I-PTPNEIPGR--DNFATAFNTSQHYLATRTYSQTFYFLTNPKEFRDCNAKVHYLAKYFV 276 Query: 918 GKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVL 1097 K ++Q+ L + +I+ AG +TT+ L Sbjct: 277 NKALNFTPEEIEEKSKSGYVFLYELVKQTRDPKVLQDQLLNIM-------VAGRDTTAGL 329 Query: 1098 LTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD------FESLSRLKIVTMIFYEVLRLYP 1259 L++ + L+ HPE K REE+ FG FESL R + + I E LR+YP Sbjct: 330 LSFAMFELARHPEIWSKLREEIEVNFGVGEESRVEEITFESLKRCEYLKAILNETLRMYP 389 Query: 1260 --PITFLTRRTYKAMELGG-------IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 P+ T + GG I P G + + H + +GKDA +F PER Sbjct: 390 SVPVNSRTATRDTTLPRGGGPNGTDPIFIPKGSTVAYIVYKTHRLEEYYGKDADDFRPER 449 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAP 1586 + + + K A+ PF GGPRIC+GQ FAL EA ++ ++Q F SP + P Sbjct: 450 WFE--PSTKKLGWAYVPFNGGPRICLGQQFALTEASYVITRLVQMFETVSSPPDVEYP 505
>P30607:CP52B_CANTR Cytochrome P450 52A2 - Candida tropicalis (Yeast)| Length = 522 Score = 101 bits (251), Expect = 1e-20 Identities = 111/432 (25%), Positives = 184/432 (42%), Gaps = 29/432 (6%) Frame = +3 Query: 426 DPELVREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKI--- 593 +P+ ++ IL+ +F F R + LL +G+ +G W R +L P F E++ Sbjct: 104 EPDNIKAILATQFNDFSLGTRHSHFAPLLGDGIFTLDGAGWKHSRSMLRPQFAREQVSHV 163 Query: 594 KRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIF 773 K + P + + + Q L F LT D + FG + E ++ Sbjct: 164 KLLEPHMQVFFKHIRKHHGQTFDIQEL--------FFRLTVDSATEFLFGESV-ESLRDE 214 Query: 774 QLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERA-IKNXX 950 + G L++ L + F + + ++N RA+ +++ IL G K+ A + Sbjct: 215 SI-GMLNDALDFDGKAGFADAFNY--SQNYLASRALMQQMYWILNGKKFKECNAKVHKFA 271 Query: 951 XXXXXXXXXXXXSNMQQSNGKANLGLSIED-----IIQECKL-FYFAGMETTSVLLTWTL 1112 +++ +G L ++ ++++ L AG +TT+ LL++ Sbjct: 272 DYYVEKALELTPDQLEKQDGYVFLYELVKQTRDRQVLRDQLLNILVAGRDTTAGLLSFVF 331 Query: 1113 IVLSMHPEWQEKAREEVLHYFGRTTP------DFESLSRLKIVTMIFYEVLRLYP--PIT 1268 L+ P K REE+ FG FESL + + + E LRLYP P Sbjct: 332 FELARTPRVANKLREEIEDKFGLGQDARVEEISFESLKSCEYLKAVLNECLRLYPSVPQN 391 Query: 1269 FLTRRTYKAMELGGIK-------YPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGI 1427 F + GG K G +M + H + I+G+DA EF PER+ + Sbjct: 392 FRVATRNTTLPRGGGKDGLSPVLVRKGQTVMYSVYAAHRNKQIYGEDALEFRPERWFE-- 449 Query: 1428 SNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFS-FELSPSYIHAPYTV--I 1598 K AF PF GGPRIC+GQ FAL EA +LQ FS + P+ ++P + + Sbjct: 450 PETKKLGWAFLPFNGGPRICLGQQFALTEASYVTVRLLQEFSHLTMDPNTEYSPKKMSHL 509 Query: 1599 TLQPQHGAQIRL 1634 T+ GA I++ Sbjct: 510 TMSLFDGANIQM 521
>Q9VQD2:CP391_DROME Probable cytochrome P450 309a1 - Drosophila melanogaster (Fruit fly)| Length = 529 Score = 101 bits (251), Expect = 1e-20 Identities = 106/423 (25%), Positives = 168/423 (39%), Gaps = 22/423 (5%) Frame = +3 Query: 357 NAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQ-RSTRIG-----RLLANG 518 N K+ + T+ P+++V DP L EIL +KF HF S+ +G + +A Sbjct: 90 NKYKDKYRTVGTFITRQPQLLVLDPALAHEILVDKFSHFRDTITSSFVGHNPDDKYVAGS 149 Query: 519 LANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQG-LCEV-DVC 692 G+KW + R ++K ++ +++ E + QG + E D+ Sbjct: 150 PFFSAGDKWKRLRSENVGGLTPSRLKMAYSIWEQSGRKLVEYIERARREQGDIIETRDLA 209 Query: 693 PEFQ-NLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRR 869 F N D I GS + +I Q ++ AF ++ + N+ Sbjct: 210 YRFTANAMADFIWGIDAGSLSGKVGEIGDFQKTSTDWSAHAFSSMI---------RFNKT 260 Query: 870 MRAIDREIRMILRGIIGKKERAIK-------NXXXXXXXXXXXXXXSNMQQSNGKANLGL 1028 + AI +R + N S++ Q + N Sbjct: 261 LVAIFVRKLFSMRFFTKATDEFFLRLTQDAVNLRQGGSGEGRTDYLSHLIQLQQRGN--- 317 Query: 1029 SIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESL 1205 SI D + + G ET+ +L L LS H E QEK R E+L ++ + Sbjct: 318 SIHDSVGHALTVHLDGFETSGAVLYHMLYSLSEHHEEQEKLRSEILEALASEGQISYDQI 377 Query: 1206 SRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELG-----GIKYPAGVNLMLPILFIHHDP 1370 + L + F E LRL PI F R K ++ + GV +M+P HHD Sbjct: 378 NNLPYLDQCFNESLRLTTPIGFFMRICTKPTQINLGDDKTLDLEPGVTVMVPAYQYHHDN 437 Query: 1371 DIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 DI+ +A EF P+RF +G ++ + F PFG GPRIC+G K A+ IL + Sbjct: 438 DIY-PEASEFRPDRFENGAASVLTKRGCFLPFGDGPRICLGMRVGQLSVKTAIVHILSNY 496 Query: 1551 SFE 1559 E Sbjct: 497 QVE 499
>Q9LTL8:C71BO_ARATH Cytochrome P450 71B24 - Arabidopsis thaliana (Mouse-ear cress)| Length = 498 Score = 101 bits (251), Expect = 1e-20 Identities = 81/307 (26%), Positives = 140/307 (45%), Gaps = 13/307 (4%) Frame = +3 Query: 681 VDVCPEFQNLTGDVISRTAFGSNFQEGM-----KIFQLQGELSERLIQAFQTLFIPGY-W 842 VD+ L G +I R+AFG F EG KI L E+ + + LF G W Sbjct: 163 VDLSQTLFGLVGSIIFRSAFGQRFDEGNHVNAEKIEDLMFEVQKLGALSNSDLFPGGLGW 222 Query: 843 F--FPTKNNRRMRAIDREIRMILRGIIGKK-ERAIKNXXXXXXXXXXXXXXSNMQQSNGK 1013 F F + +N+++ + E+ +L II + +I+ +Q G Sbjct: 223 FVDFVSGHNKKLHKVFVEVDTLLNHIIDDHLKNSIEEITHDRPDIIDSLLDMIRKQEQGD 282 Query: 1014 ANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG---RT 1184 + L+I+++ + Y AG++T+++ + W + L +P +K ++E+ G Sbjct: 283 S-FKLTIDNLKGIIQDIYLAGVDTSAITMIWAMAELVKNPRVMKKVQDEIRTCIGIKQNE 341 Query: 1185 TPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPAGVNLMLPILFIH 1361 + + + +L+ + ++ E LRL+P L R T +++ G P+ L++ + I Sbjct: 342 KIEEDDVDKLQYLKLVVKETLRLHPAAPLLLPRETMSQIKIQGYNIPSKTILLVNVWSIG 401 Query: 1362 HDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTIL 1541 DP W K+ EFNPERF D + PFG G RIC G FA+ ++ L +L Sbjct: 402 RDPKHW-KNPEEFNPERFIDCPIDYKGNSFEMLPFGSGRRICPGIAFAIATVELGLLNLL 460 Query: 1542 QRFSFEL 1562 F + L Sbjct: 461 YHFDWRL 467
>O65786:C71B4_ARATH Cytochrome P450 71B4 - Arabidopsis thaliana (Mouse-ear cress)| Length = 504 Score = 101 bits (251), Expect = 1e-20 Identities = 104/449 (23%), Positives = 181/449 (40%), Gaps = 28/449 (6%) Frame = +3 Query: 300 QPMPPGS---------HHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREIL 452 Q +PPG H + + + K+HG V G P V++ E E L Sbjct: 30 QNLPPGPAKLPIIGNLHQLQGLLHKCLHDLSKKHGPVMHLRLGFAPMVVISSSEAAEEAL 89 Query: 453 SNKFGHFGKQRSTRIGRLLAN-----GLANHEGEKWAKHRRI-LNPAFHHEKIKRMLPVF 614 + T R+ + G + G++W + R++ + F +K++ + Sbjct: 90 KTHDLECCSRPITMASRVFSRNGKDIGFGVY-GDEWRELRKLSVREFFSVKKVQSFKYIR 148 Query: 615 SACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNF-------QEGMK-- 767 + MI + + S Q VD+ LT +I RTAFG +F QE +K Sbjct: 149 EEENDLMIKKLKELASKQS--PVDLSKILFGLTASIIFRTAFGQSFFDNKHVDQESIKEL 206 Query: 768 IFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNX 947 +F+ ++ R F T + + F + ++R+ + + I+ Sbjct: 207 MFESLSNMTFRFSDFFPTAGLKWFIGFVSGQHKRLYNVFNRVDTFFNHIVDDHHSKKATQ 266 Query: 948 XXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSM 1127 N QQ A+ L+++ + Y AG++T+++ L W + L Sbjct: 267 DRPDMVDAILDMIDNEQQY---ASFKLTVDHLKGVLSNIYHAGIDTSAITLIWAMAELVR 323 Query: 1128 HPEWQEKAREEVLHYFGRTTPDF---ESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKA 1295 +P +KA++E+ G E L +L+ + ++ E LRL+P L R T Sbjct: 324 NPRVMKKAQDEIRTCIGIKQEGRIMEEDLDKLQYLKLVVKETLRLHPAAPLLLPRETMAD 383 Query: 1296 MELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGG 1475 +++ G P L++ I DP+ W K+ EFNPERF D + PFG G Sbjct: 384 IKIQGYDIPQKRALLVNAWSIGRDPESW-KNPEEFNPERFIDCPVDYKGHSFELLPFGSG 442 Query: 1476 PRICIGQNFALQEAKMALSTILQRFSFEL 1562 RIC G A+ ++ L +L F + + Sbjct: 443 RRICPGIAMAIATIELGLLNLLYFFDWNM 471
>P16141:CP52D_CANMA Cytochrome P450 52A4 - Candida maltosa (Yeast)| Length = 538 Score = 100 bits (250), Expect = 2e-20 Identities = 108/398 (27%), Positives = 167/398 (41%), Gaps = 23/398 (5%) Frame = +3 Query: 426 DPELVREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRM 602 DPE V+ IL+ +F F R + LL +G+ +G W R +L P F E++ + Sbjct: 120 DPENVKAILATQFNDFSLGTRHDFLYSLLGDGIFTLDGAGWKHSRAMLRPQFAREQVAHV 179 Query: 603 LPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQ 782 + +++ +QG D+ F LT D + FG + E ++ + Sbjct: 180 ----KLLEPHVQVLFKHVRKSQGKT-FDIQELFFRLTVDSSTEFLFGGSV-ESLRDASIG 233 Query: 783 GELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGI-IGKKERAIKNXXXXX 959 S + I A + F + + T N R + ++ IL G K + + Sbjct: 234 MVPSTKNI-AGREEFADAFNYSQTYNAYRF--LLQQFYWILNGSKFNKSIKTVHKFADFY 290 Query: 960 XXXXXXXXXSNMQQSNGKA---NLGLSIED--IIQECKL-FYFAGMETTSVLLTWTLIVL 1121 ++++ G L D ++++ L AG +TT+ LL++ L Sbjct: 291 VQKALSLTDDDLEKQEGYVFLYELAKQTRDPKVLRDQLLNILVAGRDTTAGLLSFLFFEL 350 Query: 1122 SMHPEWQEKAREEVLHYFGRTTP------DFESLSRLKIVTMIFYEVLRLYP--PITFLT 1277 S +P EK +EE+ + FG FESL + + E LR+YP P F Sbjct: 351 SRNPTVFEKLKEEIHNRFGAKEDARVEEITFESLKLCEYLKACVNEALRVYPSVPHNFRV 410 Query: 1278 RRTYKAMELGG-------IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNA 1436 + GG I G N+M I H DP I+G+DA F PER+ + Sbjct: 411 ATRNTTLPRGGGKDGMSPIAIKKGQNVMYTISATHRDPSIYGEDANVFRPERWFE--PET 468 Query: 1437 AKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF 1550 K A+ PF GGPRIC+GQ FAL EA +LQ F Sbjct: 469 RKLGWAYVPFNGGPRICLGQQFALTEASYVTVRLLQEF 506
>Q9V558:CP4P1_DROME Cytochrome P450 4p1 - Drosophila melanogaster (Fruit fly)| Length = 513 Score = 100 bits (249), Expect = 2e-20 Identities = 95/393 (24%), Positives = 164/393 (41%), Gaps = 17/393 (4%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 L GL G+KW R++L P FH + + +F ++ + ++E + D Sbjct: 125 LRTGLLTSTGKKWHARRKMLTPTFHFNILNQFQEIFKTESQKFLLQFEGQDEVT-ITLHD 183 Query: 687 VCPEFQNLTGDVISRTAFGSNFQE----GMKIFQLQGELSERLIQAFQTLFIPGYWFFPT 854 V P F T + I TA G E G + + ++ E I+ + G F Sbjct: 184 VIPRF---TLNSICETAMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLLWGDKLFEM 240 Query: 855 KNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSI 1034 + + + II K+ +K+ + ++ L + Sbjct: 241 FAAKDFASALDVVHRFSSEIIAKRRDLLKDELDKSSSTADDDGFVSKKRFAMLDTLIYAE 300 Query: 1035 ED-------IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR--TT 1187 +D I +E F G +TTS+ L + L+ +S++P+ QE +E+ + + Sbjct: 301 KDGLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLSN 360 Query: 1188 PDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELG-GIKYPAGVNLMLPILFIHH 1364 D L++LK + E RL+P + + R + EL G+ P G + + + IH Sbjct: 361 LDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHR 420 Query: 1365 DPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFALQEAKMALSTIL 1541 + W EF PERF N R A+ PF G R CIG+ +A+QE K + +L Sbjct: 421 NAKYWDSP-EEFRPERFLP--ENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLL 477 Query: 1542 QRFSF--ELSPSYIHAPYTVITLQPQHGAQIRL 1634 ++F + P I +T ITL+ Q +++L Sbjct: 478 KQFKVLKAIDPQKI-VFHTGITLRTQDKIRVKL 509
>Q9NR63:CP26B_HUMAN Cytochrome P450 26B1 - Homo sapiens (Human)| Length = 512 Score = 100 bits (249), Expect = 2e-20 Identities = 105/438 (23%), Positives = 179/438 (40%), Gaps = 16/438 (3%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQ--RSTRIGRLLANGLANHEGE 539 +++G V T P + V E VR+IL + + RSTR+ L N ++N G+ Sbjct: 78 EKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRM-LLGPNTVSNSIGD 136 Query: 540 KWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGD 719 R++ + F HE ++ LP ++ + W + A ++V E Q LT Sbjct: 137 IHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEA-----INVYQEAQKLTFR 191 Query: 720 VISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRM 899 + R G F + E L + +Q F+ + P +D Sbjct: 192 MAIRVLLG---------FSIPEEDLGHLFEVYQQ-FVDNVFSLP---------VDLPFSG 232 Query: 900 ILRGIIGKK------ERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKL 1061 RGI ++ E+AI+ + +S+ + ++++++ Sbjct: 233 YRRGIQARQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLE 292 Query: 1062 FYFAGMETTSVLLTWTLIVLSMHPEWQEKAREE-----VLHYFG---RTTPDFESLSRLK 1217 FA TT+ T ++ L HP EK R+E +LH G T ++LS L+ Sbjct: 293 LIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLR 352 Query: 1218 IVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDARE 1397 + + EV+RL+ PI+ R + EL G + P G ++M I H ++ KD Sbjct: 353 YLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVF-KDVNV 411 Query: 1398 FNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYI 1577 F+P+RF+ S + PFGGG R C+G++ A K+ + FEL+ Sbjct: 412 FDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTF 471 Query: 1578 HAPYTVITLQPQHGAQIR 1631 V L P G ++ Sbjct: 472 PRITLVPVLHPVDGLSVK 489
>Q8HYN1:CP17A_PANTR Cytochrome P450 17A1 - Pan troglodytes (Chimpanzee)| Length = 508 Score = 100 bits (249), Expect = 2e-20 Identities = 107/439 (24%), Positives = 189/439 (43%), Gaps = 23/439 (5%) Frame = +3 Query: 315 GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQR 485 GS PR M N K ++G + G V+V +L +E+L K F + Sbjct: 38 GSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRP 97 Query: 486 STRIGRLLAN---GLANHE-GEKWAKHRRILNPAFH-----HEKIKRMLPVFSACCEEMI 638 + +N G+A + G W HRR+ F +K+++++ C+E+ Sbjct: 98 QMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKII------CQEIS 151 Query: 639 TRWENSMSAQGLCEVDVC-PEFQNLTGDVISRTAFGSNFQEG---MKIFQLQGE-LSERL 803 T + + G +D+ P F +T +VIS F ++++ G + I Q E + + L Sbjct: 152 TLCDMLATHNGQ-SIDISFPVFVAVT-NVISLICFNTSYKNGDPELNIIQNYNEGIIDNL 209 Query: 804 IQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXX 983 + +P FP K ++++ + +L I+ + ++ Sbjct: 210 SKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQA 269 Query: 984 XSNMQQSNGKANLG---LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAR 1154 N N + LS I+ + AG+ETT+ ++ WTL L +P+ ++K Sbjct: 270 KMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLY 329 Query: 1155 EEVLHYFGRT-TPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPAG 1328 EE+ G + TP +RL ++ EVLRL P L + +G G Sbjct: 330 EEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKG 389 Query: 1329 VNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFA 1505 +++ + +HH+ W + +F PERF + P+ ++ PFG GPR CIG+ A Sbjct: 390 TQVIINLWALHHNEKEWHQPD-QFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILA 448 Query: 1506 LQEAKMALSTILQRFSFEL 1562 QE + ++ +LQRF E+ Sbjct: 449 RQELFLIMAWLLQRFDLEV 467
>P05093:CP17A_HUMAN Cytochrome P450 17A1 - Homo sapiens (Human)| Length = 508 Score = 100 bits (248), Expect = 3e-20 Identities = 106/439 (24%), Positives = 189/439 (43%), Gaps = 23/439 (5%) Frame = +3 Query: 315 GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQR 485 GS PR M N K ++G + G V+V +L +E+L K F + Sbjct: 38 GSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRP 97 Query: 486 STRIGRLLAN---GLANHE-GEKWAKHRRILNPAFH-----HEKIKRMLPVFSACCEEMI 638 + +N G+A + G W HRR+ F +K+++++ C+E+ Sbjct: 98 QMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKII------CQEIS 151 Query: 639 TRWENSMSAQGLCEVDVC-PEFQNLTGDVISRTAFGSNFQEG---MKIFQLQGE-LSERL 803 T + + G +D+ P F +T +VIS F ++++ G + + Q E + + L Sbjct: 152 TLCDMLATHNGQ-SIDISFPVFVAVT-NVISLICFNTSYKNGDPELNVIQNYNEGIIDNL 209 Query: 804 IQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXX 983 + +P FP K ++++ + +L I+ + ++ Sbjct: 210 SKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQA 269 Query: 984 XSNMQQSNGKANLG---LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAR 1154 N N + LS I+ + AG+ETT+ ++ WTL L +P+ ++K Sbjct: 270 KMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLY 329 Query: 1155 EEVLHYFGRT-TPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPAG 1328 EE+ G + TP +RL ++ EVLRL P L + +G G Sbjct: 330 EEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKG 389 Query: 1329 VNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFA 1505 +++ + +HH+ W + +F PERF + P+ ++ PFG GPR CIG+ A Sbjct: 390 TEVIINLWALHHNEKEWHQPD-QFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILA 448 Query: 1506 LQEAKMALSTILQRFSFEL 1562 QE + ++ +LQRF E+ Sbjct: 449 RQELFLIMAWLLQRFDLEV 467
>Q9V774:C6A21_DROME Probable cytochrome P450 6a21 - Drosophila melanogaster (Fruit fly)| Length = 504 Score = 100 bits (248), Expect = 3e-20 Identities = 100/407 (24%), Positives = 179/407 (43%), Gaps = 15/407 (3%) Frame = +3 Query: 387 FTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGR--LLANGLANHEGEKWAKHRR 560 F WF P V V + L ++IL +F F + L+ L +G+KW R Sbjct: 75 FYWFR-RPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWRTMRN 133 Query: 561 ILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAF 740 L+ F K+K M P E + +++ + EV T DVI AF Sbjct: 134 KLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVREL--LARFTTDVIGTCAF 191 Query: 741 G---SNFQEGMKIFQLQGE--LSERLIQAFQTLFIPGYWFFPTKNNRRMRA--IDREIRM 899 G S+ ++ F+ G L+E+ + F+ + + + +M A I+R Sbjct: 192 GIECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLHMKMTAEPIERFFMR 251 Query: 900 ILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGM 1079 I+R + +E+ M +G++ + L+IE+I + +F+ AG Sbjct: 252 IVRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSGES-VNLTIEEIAAQAFVFFAAGF 310 Query: 1080 ETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPD--FESLSRLKIVTMIFYEVLRL 1253 ET+S + + L L+ + + Q + R+E + + +ES+ L + + E LRL Sbjct: 311 ETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRL 370 Query: 1254 YPPITFLTRRTYKAMELGGI-KY--PAGVNLMLPILFIHHDPDIWGKDAREFNPERFADG 1424 Y + L R + E+ G KY G+ +++P +H D ++ + FNP+ F+ Sbjct: 371 YTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYA-NPNTFNPDNFSP- 428 Query: 1425 ISNAAKRPAA-FFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 +R + + PFG GPR CIG F +A++ L+ +++ F F + Sbjct: 429 -ERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSV 474
>P43083:CP52V_CANAP Cytochrome P450 52E1 - Candida apicola (Yeast)| Length = 519 Score = 99.8 bits (247), Expect = 4e-20 Identities = 64/173 (36%), Positives = 86/173 (49%), Gaps = 12/173 (6%) Frame = +3 Query: 1071 AGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRT---TPDFESLSRLKIVTMIFYE 1241 AG +TT+ LL++ L +PE + RE VL FG T TP FE L + K++ + E Sbjct: 312 AGRDTTAGLLSFITYYLGAYPEVYAELREAVLSEFGSTDVETPTFEQLKQCKVLQNVIRE 371 Query: 1242 VLRLYP--PITFLTRRTYKAMELGG-------IKYPAGVNLMLPILFIHHDPDIWGKDAR 1394 VLRL+P P+ F + GG + P G N+ + DIWG DA Sbjct: 372 VLRLHPNVPLNFRQAIVDTKLPTGGGPNGDQPVFVPKGQNVFYSTYSMQRRTDIWGPDAT 431 Query: 1395 EFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFS 1553 F P+R+ + A + PF GGPRIC+GQ FAL EA + I Q FS Sbjct: 432 TFRPDRWNEP-REALASGWDYIPFNGGPRICLGQQFALTEASYTIVRICQEFS 483 Score = 33.9 bits (76), Expect = 2.4 Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 4/112 (3%) Frame = +3 Query: 426 DPELVREILSNKFGHF--GKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKR 599 +PE ++ +L+ F + G + G LL NG+ G+ W R +L P F E++ Sbjct: 98 EPENIKTVLATSFKDYSLGFRYDIMYG-LLGNGIFTLSGDGWKHSRALLRPQFSREQVSH 156 Query: 600 MLPVFSACCEEMITRWENSMS--AQGLCEVDVCPEFQNLTGDVISRTAFGSN 749 + E M T ++ +G VD + NLT D + FG + Sbjct: 157 L--------ESMRTHINLMINNHFKGGQVVDAQALYHNLTIDTATEFLFGES 200
>P95099:CP136_MYCTU Putative cytochrome P450 136 - Mycobacterium tuberculosis| Length = 492 Score = 99.8 bits (247), Expect = 4e-20 Identities = 62/180 (34%), Positives = 91/180 (50%), Gaps = 1/180 (0%) Frame = +3 Query: 1038 DIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLK 1217 DI+ A +T++ T L+ HPEWQ++ R+E + G D ESL +L+ Sbjct: 292 DIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRH-GDGPLDIESLEQLE 350 Query: 1218 IVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDARE 1397 + ++ E +RL P+ + R+T + EL G P G N++ H P+IW D Sbjct: 351 SLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIW-TDPLT 409 Query: 1398 FNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELS-PSY 1574 F+PERF + + + AF PFGGG CIG F E K L +L+R+ ELS P Y Sbjct: 410 FDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDY 469
>Q9STL0:C71AN_ARATH Cytochrome P450 71A23 - Arabidopsis thaliana (Mouse-ear cress)| Length = 483 Score = 99.4 bits (246), Expect = 5e-20 Identities = 94/408 (23%), Positives = 172/408 (42%), Gaps = 12/408 (2%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLA----NGLANHEGE 539 +G + FG P ++ E R++L F + ++I L N + GE Sbjct: 60 YGPLMLLHFGSVPVIVASTAEAARDVLKTHDRVFASRPRSKIFEKLLYKSRNMASAPYGE 119 Query: 540 KWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGD 719 W R++ + + H +M+ F +E IT ++ V++ +LT D Sbjct: 120 YW---RQMKSVSVLHLLSNKMVRSFQDVRQEEITLMMETIRKSSSKPVNLSKILSSLTND 176 Query: 720 VISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTLFIPGY--WFFPTK----NNRRMRAI 881 VI R A G + G EL +RL++ T I Y W T R+ Sbjct: 177 VICRVALGRKYGVGTDF----KELIDRLMRQLGTFTIGSYVPWLAWTDWVSGLEARLEKT 232 Query: 882 DREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKL 1061 + +L I+ E + + +S G LSI+ I+ + Sbjct: 233 ANDFDKLLERIVQDHE----DGDGDKTDFVDVLLAAQRDKSFGFDIDRLSIKAIVLDA-- 286 Query: 1062 FYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIFY 1238 + G +T+S L+ W + L HP +K +EEV G+++ + + ++ + + Sbjct: 287 -FVGGTDTSSTLVEWEMTELLRHPTCLKKLQEEVRTICKGKSSVSEDDIQGMEYLKAVVK 345 Query: 1239 EVLRLYPPITFLT-RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF 1415 E LRL+PP+ + ++ + + L PAG +++ + + + WG DA EF PER Sbjct: 346 EALRLHPPVPLMVPHQSTQDVRLRDNHIPAGTQVIVNLWAVGREAATWGPDANEFRPERH 405 Query: 1416 ADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 + S+ + PFG G R+C G +FA+ ++ L+ ++ F ++ Sbjct: 406 LESPSDFRGQDFELIPFGAGRRMCPGISFAVVLNEVVLANLVHGFDWQ 453
>Q42716:C71A8_MENPI Cytochrome P450 71A8 - Mentha piperita (Peppermint)| Length = 502 Score = 99.4 bits (246), Expect = 5e-20 Identities = 107/448 (23%), Positives = 174/448 (38%), Gaps = 26/448 (5%) Frame = +3 Query: 297 SQPMPPGSHHIAPRVLPMFTNAI--------------KEHGKVSFTWFGPTPRVMVPDPE 434 + P S +PR LP+ N + ++HG + G V Sbjct: 41 NSPKNKNSSPPSPRKLPILGNLLQLGSLPHHNLRSMARKHGPIMLLHLGSVRPVS--SRR 98 Query: 435 LVREILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRI-LNPAFHHEKIKRMLPV 611 R N + R +R L G GE W + + I + +++++ V Sbjct: 99 RPRGNHENSRSRLRRPRGSRSAALQLQGRVGGYGEYWRQLKTICVVQLLSNKRVQSFRSV 158 Query: 612 FSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNF----QEGMKIFQL 779 E ++ + +S V++ F LT DV+ R+A G + + G K ++ Sbjct: 159 REEETELLMKKIGDSSG-----NVNLSHMFTQLTNDVVCRSAIGRKYGAGDENGEKFLEI 213 Query: 780 QGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXX 959 E E L F+P W+ R+ DR + I + + E+ I Sbjct: 214 LREFLELLGAISIGDFVPSLWWI-----NRINGFDRRVDRIAKEMDEFLEKVIHERLENP 268 Query: 960 XXXXXXXXXSNMQQSNGKANLGLSIE-DIIQECKLFYFA-GMETTSVLLTWTLIVLSMHP 1133 + + + G+SI+ D I+ L FA G +TT+V+L W + L HP Sbjct: 269 AAKAEENFVDILLEIYRNNSAGVSIDRDSIKAIILDVFAAGTDTTAVVLEWAMTELLRHP 328 Query: 1134 EWQEKAREEVLHYF----GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKA-M 1298 E +K + EV T D E + LK V E +R + PI L R + + Sbjct: 329 EIMKKLQSEVRQVVKDKHNITDDDIEKMHYLKAVMK---ETMRFHTPIPLLVPRVARNDV 385 Query: 1299 ELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGP 1478 E+ G P G +M+ I DP W + +F PERF + + PFG G Sbjct: 386 EVMGYDVPVGTMVMINAWAIGRDPTSWD-EPEKFRPERFLNSSVDFKGLDFELIPFGAGR 444 Query: 1479 RICIGQNFALQEAKMALSTILQRFSFEL 1562 R C G F + + L+ ++Q+F +EL Sbjct: 445 RGCPGTTFPMATLEFTLANLMQKFDWEL 472
>Q04552:CP6B1_PAPPO Cytochrome P450 6B1 - Papilio polyxenes (Black swallowtail butterfly)| Length = 498 Score = 99.0 bits (245), Expect = 6e-20 Identities = 93/403 (23%), Positives = 160/403 (39%), Gaps = 16/403 (3%) Frame = +3 Query: 405 TPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHH 584 TP V++ D ++++ +L F F + L + + +G++W R P F Sbjct: 77 TPSVLLRDLDIIKHVLIKDFESFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTS 136 Query: 585 EKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGM 764 K+K MLP+ S + I + Q E + Q T I+ FG N EGM Sbjct: 137 GKLKSMLPLMSQVGDRFINSIDEVSQTQP--EQSIHNLVQKFTMTNIAACVFGLNLDEGM 194 Query: 765 --KIFQLQGELSERLIQAFQTLFIPGYW------FFPTKNNRRMRAIDREIRMILRGIIG 920 + L + A + PG FP ++ + + + + +G Sbjct: 195 LKTLEDLDKHIFTVNYSAELDMMYPGILKKLNGSLFPKVVSKFFDNLTKNVLEMRKGTPS 254 Query: 921 KKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLL 1100 ++ I S ++ L L+ I + +FY AG ET++ + Sbjct: 255 YQKDMID--LIQELREKKTLELSRKHENEDVKALELTDGVISAQMFIFYMAGYETSATTM 312 Query: 1101 TWTLIVLSMHPEWQEKAREEVLHYFGRTTPD--FESLSRLKIVTMIFYEVLRLYPPITFL 1274 T+ L+ +P+ Q+K E+ R + +E LS + ++ +F E LR YP F Sbjct: 313 TYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLSEMTYLSKVFDETLRKYPVADFT 372 Query: 1275 TRRTYKAMELGG--IKYPAGVNLMLPILFIHHDPDIWGK----DAREFNPERFADGISNA 1436 R G I G +++ I +DP + D FNPE D Sbjct: 373 QRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENVKD----- 427 Query: 1437 AKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELS 1565 + P A+ PF GPR C+G FA ++++ + +L ++ E S Sbjct: 428 -RHPCAYLPFSAGPRNCLGMRFAKWQSEVCIMKVLSKYRVEPS 469
>Q4V8D1:CP2U1_RAT Cytochrome P450 2U1 - Rattus norvegicus (Rat)| Length = 530 Score = 99.0 bits (245), Expect = 6e-20 Identities = 101/414 (24%), Positives = 165/414 (39%), Gaps = 17/414 (4%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANG---LANHEGEK 542 +G + + G V++ D + VRE L + F + + +L + H G Sbjct: 100 YGNIFSFFIGHRLVVVLSDFQSVREALVQQAEVFSDRPRMPLISILTKEKGIVFAHYGPI 159 Query: 543 WAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDV 722 W + RR + H + + L + EE + M G P N ++ Sbjct: 160 WKQQRRFSHSTLRHFGLGK-LSLEPRIIEEF-AYVKAEMQKHGEAPFSPFPVISNAVSNI 217 Query: 723 ISRTAFGSNFQEGMKIFQLQGELSERLI------QAFQTLFIPGYWFFPTKNNRRMRAID 884 I FG F K F+ + R + Q F P +++ P + +R I+ Sbjct: 218 ICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINLCPWFYYLPFGPFKELRQIE 277 Query: 885 REIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLF 1064 R+I L+ II + + ++ + Q+ K G + + E LF Sbjct: 278 RDITCFLKNIIKEHQESLDANNPQDFIDMYLL---HTQEEKDKCK-GTNFD----EDYLF 329 Query: 1065 YF------AGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIV 1223 Y AG +TT+ L W L+ +S++P Q+K EE+ GR P +++ Sbjct: 330 YIIGDLFIAGTDTTTNSLLWCLLYMSLNPGVQKKVHEEIERVIGRDRAPSLTDKAQMPYT 389 Query: 1224 TMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREF 1400 EV RL + + T + L G P G ++ + IH DP IW K +F Sbjct: 390 EATIMEVQRLSMVVPLAIPHMTSEKTVLQGYSIPKGTVVLPNLWSIHRDPVIWEK-PDDF 448 Query: 1401 NPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 P RF D KR F PFG G R+C+G+ A E + +++Q F+F L Sbjct: 449 CPHRFLDDQGQLLKR-ETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFAL 501
>O49340:C71AC_ARATH Cytochrome P450 71A12 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 99.0 bits (245), Expect = 6e-20 Identities = 101/419 (24%), Positives = 170/419 (40%), Gaps = 24/419 (5%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANG----LANHEGE 539 +G + FG P ++V E +E+L F + ++ L NG + GE Sbjct: 64 YGPLMLLHFGRVPILVVSSGEAAQEVLKTHDLKFANRPRSKAVHGLMNGGRDVVFGPYGE 123 Query: 540 KWAKHRRILNPAFHHEKIKRMLPVFSACCEE----MITRWE---NSMSAQGLCEVDVCPE 698 W R++ + + +M+ F EE MI + E +S S++ L E+ Sbjct: 124 YW---RQMKSVCILNLLTNKMVASFEKIREEELNEMIKKLEKASSSSSSENLSEL----- 175 Query: 699 FQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTL-------FIPGYWFFPTK 857 F L DV SR A G E + +L +R+ Q + L ++P + Sbjct: 176 FVTLPSDVTSRIALGRKHSED----ETARDLKKRVRQIMELLGEFPIGDYVPALAWID-- 229 Query: 858 NNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIE 1037 R+ + I+ + +G ++ ++ +S + Sbjct: 230 ---RINGFNARIKEVSQGFSDLMDKVVQEHLEAGNHKEDFVDILLSIESEKSIGFQAQRD 286 Query: 1038 DIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVL-----HYFGRTTPDFES 1202 DI + G T+S LL W + L +P +K ++E+ H D E+ Sbjct: 287 DIKFMILDMFIGGTSTSSTLLEWIMTELIRNPNVMKKLQDEIRSTIRPHGSYIKEKDVEN 346 Query: 1203 LSRLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIW 1379 + LK V EV R++PP+ L R + +++ G AG +++ I DP IW Sbjct: 347 MKYLKAVIK---EVFRVHPPLPLILPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDPAIW 403 Query: 1380 GKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 G DA EF PER D + + F PFG G RIC G N AL ++ ++ ++ RF + Sbjct: 404 GPDAEEFKPERHLDSTLDYHGKDLNFIPFGSGRRICPGINLALGLVEVTVANLVGRFDW 462
>Q0IIF9:CP2U1_BOVIN Cytochrome P450 2U1 - Bos taurus (Bovine)| Length = 543 Score = 98.6 bits (244), Expect = 8e-20 Identities = 90/395 (22%), Positives = 159/395 (40%), Gaps = 12/395 (3%) Frame = +3 Query: 414 VMVPDPELVREILSNKFGHFGKQRSTRIGRLLANG---LANHEGEKWAKHRRILNPAFHH 584 V++ D VRE L + F + + ++ G + H G W + R+ + H Sbjct: 128 VVLNDFHSVREALVQQAEVFSDRPRVPLTSIMTKGKGIVFAHYGPVWRQQRKFSHSTLRH 187 Query: 585 EKIKRMLPVFSACCEEMITRW-ENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEG 761 + + L + EE R+ + M G + P N ++I FG F Sbjct: 188 FGLGK-LSLEPKIIEEF--RYVKEEMQKHGDAPFNPFPIVNNAVSNIICSLCFGRRFDYT 244 Query: 762 MKIFQLQGELSERLIQAF---QTLFI---PGYWFFPTKNNRRMRAIDREIRMILRGIIGK 923 F+ R ++ Q L + ++ P + +R I++++ + L+ II Sbjct: 245 NSEFKQMLNFMSRALEVCLNTQLLLVNICSWLYYLPFGPFKELRQIEKDLTLFLKKIIKD 304 Query: 924 KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLT 1103 ++ +++N +N G + + + AG +TT+ L Sbjct: 305 HRESLDVENPQDFIDMYLLHVEEEKKNN--SNSGFDEDYLFYIIGDLFIAGTDTTTNSLL 362 Query: 1104 WTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIFYEVLRLYPPITF-LT 1277 W L+ +S+HP QEK EE+ G P +++ EV RL + + Sbjct: 363 WCLLYMSLHPNIQEKIHEEIARVIGADRAPSLTDKAQMPYTEATIMEVQRLSTVVPLSIP 422 Query: 1278 RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAF 1457 T + L G P G ++ + +H DP IW K +F P+RF D K+ F Sbjct: 423 HMTSEKTVLQGFTIPKGTIILPNLWSVHRDPAIWEK-PNDFYPDRFLDDQGQLIKK-ETF 480 Query: 1458 FPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 PFG G R+C+G+ A E + +++Q F+F L Sbjct: 481 IPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFVL 515
>Q64403:CP2DG_CAVPO Cytochrome P450 2D16 - Cavia porcellus (Guinea pig)| Length = 500 Score = 98.6 bits (244), Expect = 8e-20 Identities = 66/214 (30%), Positives = 100/214 (46%), Gaps = 7/214 (3%) Frame = +3 Query: 990 NMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLH 1169 N + S NL L + D+ + AGM TTSV L+W L+++ +HP+ Q +EE+ Sbjct: 288 NSESSFNDENLRLLVSDL-------FGAGMVTTSVTLSWALLLMILHPDVQRHVQEEIDE 340 Query: 1170 YFGRTT-PDFESLSRLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLML 1343 G+ P+ + + + +EV R + + T + E+ G P G L Sbjct: 341 VIGQVRCPEMADQAHMPFTNAVIHEVQRFADIVPMGVPHMTSRDTEVQGFLIPKGTMLFT 400 Query: 1344 PILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKM 1523 + + D +W K F+P F D KR A F PF GPRIC+G+ A E + Sbjct: 401 NLSSVLKDETVWEKPLH-FHPGHFLDAEGRFVKREA-FMPFSAGPRICLGEPLARMELFL 458 Query: 1524 ALSTILQRFSFEL-----SPSYIHAPYTVITLQP 1610 +++LQRFSF + PS APY V+ P Sbjct: 459 FFTSLLQRFSFSVPEGQPRPSDRGAPYLVVLPSP 492
>Q9SCN2:C71BU_ARATH Cytochrome P450 71B31 - Arabidopsis thaliana (Mouse-ear cress)| Length = 498 Score = 98.6 bits (244), Expect = 8e-20 Identities = 102/461 (22%), Positives = 174/461 (37%), Gaps = 22/461 (4%) Frame = +3 Query: 246 LFTGDIPENSRFNAEARSQPMPPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVP 425 LF +P + P+ H + + EHG V +G P + Sbjct: 17 LFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFS 76 Query: 426 DPELVREILSNKFGHFGKQRSTRIGRLLANGLANHE---------GEKWAKHRRILN-PA 575 E +E+L + +L+ANGL H GE+W + ++ + Sbjct: 77 SNEAAKEVLKTH-----DLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLEL 131 Query: 576 FHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQ 755 F +K K + + ++ + N Q L VD+ + T +I R AFG NF+ Sbjct: 132 FSPKKHKSFRYIREEEGDLLVKKISNYAQTQTL--VDLRKSLFSYTASIIFREAFGQNFR 189 Query: 756 EGM-----KIFQLQGELSERLIQ-AFQTLFIPGYWFFPTK---NNRRMRAIDREIRMILR 908 E K+ +L E + AF F G + + + RM ++ Sbjct: 190 ECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFE 249 Query: 909 GIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETT 1088 +I + +K + + +L ++ + +I AG+ Sbjct: 250 DVI---DELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAG 306 Query: 1089 SVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDF--ESLSRLKIVTMIFYEVLRLYPP 1262 +V + WT+ L+ HP +K +EE+ G E L +++ + ++ E RL+PP Sbjct: 307 TVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPP 366 Query: 1263 ITFLT-RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAA 1439 L R T +E+ G P ++ + I DP W + EFNPERF + N Sbjct: 367 APLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRW-TNPEEFNPERFLNTSINYK 425 Query: 1440 KRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + PFG G R C G + ++ L IL F + L Sbjct: 426 GQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSL 466
>Q9T0K2:C71AK_ARATH Cytochrome P450 71A20 - Arabidopsis thaliana (Mouse-ear cress)| Length = 495 Score = 98.6 bits (244), Expect = 8e-20 Identities = 100/419 (23%), Positives = 173/419 (41%), Gaps = 22/419 (5%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRI-GRLLANG----LANHEG 536 +G + FG TP ++V ++ +++ + T++ ++L+ G A + G Sbjct: 61 YGPLMLLHFGRTPVLIVSSADVAHDVMKTHDLVCANRPKTKVVDKILSGGRDVAFAPY-G 119 Query: 537 EKWAKHRRI-LNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLT 713 E W + + I + +++ ++ + + MI + E + + V++ LT Sbjct: 120 EYWRQMKSICIQNLLNNKMVRSYEKIREEEIKRMIEKLEKASCSSSPSPVNLSQILMTLT 179 Query: 714 GDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTL--------FIPGY-WFFPTKN-N 863 D+I R A G + G K G E +++ F L +IP W + + Sbjct: 180 NDIICRVALGRKYS-GKK----DGIDVENIVRTFAALLGEFPVGEYIPSLSWIDRIRGLD 234 Query: 864 RRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSN-GKANLGLSIED 1040 +M +D+ L ++ + E A K Q K+ L L I D Sbjct: 235 HKMEVVDKRFDEFLERVVKEHEEADKETRSDLVDKLLTIQSDKTGQFELEKSALKLIIWD 294 Query: 1041 IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR----TTPDFESLS 1208 + + AG TT L W + L +P+ +K +EE+ + T + E ++ Sbjct: 295 M-------FLAGTATTLSFLEWAMTELMRNPKVMKKLQEEIRSSSPQDLFVTEKEAEKMN 347 Query: 1209 RLKIVTMIFYEVLRLYPPITFLTRRTYKA-MELGGIKYPAGVNLMLPILFIHHDPDIWGK 1385 L+ V E LRL PP L R ++L G PAG +++ I D WG Sbjct: 348 YLQAVIK---EALRLRPPAPLLVPRVLSEDVKLKGYNIPAGTQVIVNAWAIQRDTTTWGT 404 Query: 1386 DAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 DA EF PER D + + F PFG G RIC G F + L+ I++RF++ + Sbjct: 405 DAEEFKPERHLDTNLDFQGQDFKFIPFGSGKRICPGIGFTSALIGVTLANIVKRFNWRM 463
>Q9LIP4:C71BX_ARATH Cytochrome P450 71B36 - Arabidopsis thaliana (Mouse-ear cress)| Length = 500 Score = 98.2 bits (243), Expect = 1e-19 Identities = 108/453 (23%), Positives = 182/453 (40%), Gaps = 30/453 (6%) Frame = +3 Query: 294 RSQPMPPGS------HHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILS 455 R P PPG H + K++G V FG P V+V E +++L Sbjct: 30 RKPPSPPGFPIIGNLHQLGELPHQSLWRLSKKYGHVMLLKFGSIPTVVVSSSETAKQVLK 89 Query: 456 NKFGHFGKQRSTRIGRLLANGLANHE----GEKWAKHRRI-LNPAFHHEKIKRMLPVFSA 620 H + S R L+ + + W + RRI + F ++++ P+ Sbjct: 90 IHDLHCCSRPSLAGPRALSYNYLDIAFSPFDDYWKELRRICVQELFSVKRVQSFQPIKED 149 Query: 621 CCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSER 800 +++I S S QG V++ +F +LT V + FG NFQ + L + E+ Sbjct: 150 EVKKLIDSVSESAS-QGT-PVNLSEKFTSLTVRVTCKATFGVNFQGTV----LNSDRFEK 203 Query: 801 LIQAFQTLFIPGYW---FFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXX 971 LI LF+ + +FP I L G+ G++ER+++ Sbjct: 204 LIHDTY-LFLGSFSASDYFPNGG---------WIIDWLTGLHGQRERSVRALDAFYEQMF 253 Query: 972 XXXXXSNMQQSNGKANLGLSIED---IIQECKL-----------FYFAGMETTSVLLTWT 1109 N + +L L +E +I KL G+ T+++ +TW Sbjct: 254 DLHKQGNKEGVEDFVDLLLRLEKEETVIGYGKLTRNHIKAILMNVLIGGIGTSAITMTWA 313 Query: 1110 LIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSRLKIVTMIFYEVLRLYPPITFLT-RR 1283 + L +P +K + E+ + G+ + + + +L + M+ E RL+PP FL R+ Sbjct: 314 MTELMRNPRVMKKVQSEIRNQIGKKSMITLDDIDQLHYLKMVINETWRLHPPSPFLIPRQ 373 Query: 1284 TYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFP 1463 EL P L + + I DPD W KD EF PERF + +A + P Sbjct: 374 VMSEFELNDYVIPVKTRLYVNVWAIGRDPDTW-KDPEEFLPERFVNSSIDAKGQHFELLP 432 Query: 1464 FGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 FG G R+C + L+ +L F +++ Sbjct: 433 FGSGRRMCPAMYMGTTMVEFGLANMLYHFDWKI 465
>O49342:C71AD_ARATH Cytochrome P450 71A13 - Arabidopsis thaliana (Mouse-ear cress)| Length = 497 Score = 98.2 bits (243), Expect = 1e-19 Identities = 100/414 (24%), Positives = 174/414 (42%), Gaps = 17/414 (4%) Frame = +3 Query: 372 HGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANG----LANHEGE 539 +G + FG P ++V E +E+L F + ++ L NG + GE Sbjct: 64 YGPLMLLHFGRVPILVVSSGEAAQEVLKTHDHKFANRPRSKAVHGLMNGGRDVVFAPYGE 123 Query: 540 KWAKHRRILNPAFHHEKIKRMLPVFSACCEE----MITRWE---NSMSAQGLCEVDVCPE 698 W R++ + + +M+ F E+ MI + E +S S++ L E+ Sbjct: 124 YW---RQMKSVCILNLLTNKMVESFEKVREDEVNAMIEKLEKASSSSSSENLSEL----- 175 Query: 699 FQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTL--FIPGYWFFPTKNNRRM 872 F L DV SR A G E + +L +R+ Q + L F G + + Sbjct: 176 FITLPSDVTSRVALGRKHSED----ETARDLKKRVRQIMELLGEFPIGEYVPILAWIDGI 231 Query: 873 RAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQE 1052 R + +I+ + RG ++ ++ + + + + DI Sbjct: 232 RGFNNKIKEVSRGFSDLMDKVVQEHLEASNDKADFVDILLSIEKDKNSGFQVQRNDIKFM 291 Query: 1053 CKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEV---LHYFGRTTPDFESLSRLKIV 1223 + G TTS LL WT+ L P+ +K ++E+ + G + E + +K + Sbjct: 292 ILDMFIGGTSTTSTLLEWTMTELIRSPKSMKKLQDEIRSTIRPHGSYIKEKE-VENMKYL 350 Query: 1224 TMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREF 1400 + EVLRL+P + L R + +++ G AG +++ I D IWG DA EF Sbjct: 351 KAVIKEVLRLHPSLPMILPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDTAIWGPDAEEF 410 Query: 1401 NPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 PER D + + + PFG G RIC G N AL A++ ++ ++ RF + + Sbjct: 411 KPERHLDSGLDYHGKNLNYIPFGSGRRICPGINLALGLAEVTVANLVGRFDWRV 464
>O46054:C4AE1_DROME Cytochrome P450 4ae1 - Drosophila melanogaster (Fruit fly)| Length = 496 Score = 98.2 bits (243), Expect = 1e-19 Identities = 101/396 (25%), Positives = 163/396 (41%), Gaps = 19/396 (4%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 L +GL G++W R+I+ P FH +++ + VF ++ R + G V+ Sbjct: 113 LGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRT--LSYGNEVVN 170 Query: 687 VCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSE------RLIQAFQTLFIPGYWFF 848 + P D+I+ TA G N QG SE L T F+ + F Sbjct: 171 IYPLVGLAALDIITETAMGVN-------VDAQGADSEVVHAVKDLTNILATRFMRPHLLF 223 Query: 849 P-------TKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSN 1007 P R+ +A + GII ++ R + + ++ Sbjct: 224 PHLFRLCWPSGFRKQQAGVICLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLLRAT 283 Query: 1008 GKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-- 1181 L+ + I E F F G +TT+ +++ L +LS H Q+K EE+ ++G+ Sbjct: 284 VDGQ-PLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDL 342 Query: 1182 ----TTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPI 1349 DF +L L V E LRLYPPI + R K + + P G N+++ + Sbjct: 343 FRGVILSDFATLPYLSCVVK---ESLRLYPPIPAVARCLEKDLVIDEGYIPVGTNVVVLL 399 Query: 1350 LFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMAL 1529 + D I+ D F PER G P ++ PF GPR CIGQ FAL E K + Sbjct: 400 WQLLRDEAIF-TDPLVFQPERHL-GEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMV 457 Query: 1530 STILQRFSFELSPSYIHAPYTVITLQPQHGAQIRLK 1637 + +++ + L P I L+ + G + L+ Sbjct: 458 TKVIRHYQL-LPMGADVEPSIKIVLRSKSGVNVGLR 492
>Q29497:CP17A_SHEEP Cytochrome P450 17A1 - Ovis aries (Sheep)| Length = 509 Score = 97.8 bits (242), Expect = 1e-19 Identities = 112/472 (23%), Positives = 196/472 (41%), Gaps = 33/472 (6%) Frame = +3 Query: 294 RSQPMPP--GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSN 458 RS P P GS PR N K ++G + G VM+ +L RE+L Sbjct: 29 RSLPSLPLVGSLPFLPRRGQQHENFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLK 88 Query: 459 KFGHF-GKQRSTRIGRLLAN----GLANHEGEKWAKHRRILNPAFH-----HEKIKRML- 605 K F G+ + + L N A+H G W HR+++ AF + K+++++ Sbjct: 89 KGKEFSGRPKVATLDILSDNQKGIAFADH-GAHWQLHRKLVLNAFALFKDGNLKLEKIIN 147 Query: 606 PVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQE---GMKIFQ 776 + C+ + T+ S +D+ ++IS F +F+ +K Q Sbjct: 148 QEANVLCDFLATQHGQS--------IDLSEPLSLAVTNIISFICFNFSFKNEDPALKAIQ 199 Query: 777 -LQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXX 953 + + E L + P FP+K +M+ +L I+ K + + Sbjct: 200 NVNDGILEVLGKEVLLDIFPALKIFPSKAMEKMKGCVETRNELLSEILEKCQENFTSDSI 259 Query: 954 XXXXXXXXXXXSNMQQSNGKANLG---LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLS 1124 N +N LS ++ + AG+ETT+ ++ W + L Sbjct: 260 TNLLHILMQAKVNADNNNTGPEQDSKLLSNRHMLATIADIFGAGVETTTSVIKWIVAYLL 319 Query: 1125 MHPEWQEKAREEVLHYFG-RTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAM- 1298 HP +++ ++ + G TP +RL ++ EVLR+ P L +KA+ Sbjct: 320 HHPSLKKRIQDSIDQNIGFNRTPTISDRNRLVLLEATIREVLRIRPVAPMLI--PHKAII 377 Query: 1299 --ELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFG 1469 +G + G ++++ + +HH+ W + F PERF D P+ ++ PFG Sbjct: 378 DSSIGDLTIDKGTDVVVNLWALHHNEKEW-QQPDLFMPERFLDPTGTQLISPSLSYLPFG 436 Query: 1470 GGPRICIGQNFALQEAKMALSTILQRFSFELS-----PSYIHAPYTVITLQP 1610 GPR C+G+ A QE + +S +LQRF+ E+ PS P V+ ++P Sbjct: 437 AGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDDGKLPSLEGNPSLVLQIKP 488
>Q9LIP5:C71BW_ARATH Cytochrome P450 71B35 - Arabidopsis thaliana (Mouse-ear cress)| Length = 500 Score = 97.8 bits (242), Expect = 1e-19 Identities = 107/462 (23%), Positives = 186/462 (40%), Gaps = 31/462 (6%) Frame = +3 Query: 270 NSRFNAEARSQPMPPGS------HHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDP 431 N + + + R P PPG H I K++G V G P V+V Sbjct: 21 NHKKHPKYRQFPCPPGFPIIGNLHQIGELPHQTLWKLSKKYGPVMHLMLGRVPTVVVSSS 80 Query: 432 ELVREILSNKFGHFGKQRSTRIGRLLANGLANHE----GEKWAKHRRI-LNPAFHHEKIK 596 + R++L H + S R L+ + + W + R++ + F +++ Sbjct: 81 DTARQVLRVHDLHCCTRPSLSGPRELSYNYLDIAFSPYDDYWKEVRKLCVQELFSTKQVH 140 Query: 597 RMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGM---- 764 + P+ ++MI S S + V++ + LT V+ RTAFG +F+ + Sbjct: 141 SIQPIKDEEVKKMIDSIAESASQKN--PVNLNNKCLELTVSVVCRTAFGVSFEGTVLNSD 198 Query: 765 KIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKN 944 + ++ E E L FIP + ID +L G+ G++ER+ ++ Sbjct: 199 RFNKIVREALEMLGSFSAADFIPYVGWI----------ID-----VLTGLQGRRERSKRD 243 Query: 945 XXXXXXXXXXXXXXSNMQQSNGKANLGLSIED---IIQECKL-----------FYFAGME 1082 + + +L L +E ++ KL AG++ Sbjct: 244 LNAFFEQMFDLHKEGKKEGNEDFVDLLLRLEKEEAVLGNDKLTRNHIKAILLDVLLAGID 303 Query: 1083 TTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG-RTTPDFESLSRLKIVTMIFYEVLRLYP 1259 T+++ +TW + L+ +P +K + E+ G R+ FE + +L+ + M+ E RL+P Sbjct: 304 TSAITMTWAMTELARNPRVMKKVQSEIRTQMGNRSMISFEDMDQLEYLKMVIKETWRLHP 363 Query: 1260 PITFLT-RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNA 1436 L R ++ G P L + + I DPD W KD F PERF D +A Sbjct: 364 TTPLLLPREAMSEFDINGYTIPVKTRLHVNVWAIGRDPDTW-KDPEVFLPERFMDNNIDA 422 Query: 1437 AKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + PFGGG RIC + L+ +L F ++L Sbjct: 423 KGQHFELLPFGGGRRICPAIYMGTTMVEFGLANLLYHFDWKL 464
>Q9LTL2:C71BP_ARATH Cytochrome P450 71B25 - Arabidopsis thaliana (Mouse-ear cress)| Length = 501 Score = 97.8 bits (242), Expect = 1e-19 Identities = 98/437 (22%), Positives = 177/437 (40%), Gaps = 17/437 (3%) Frame = +3 Query: 303 PMPPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQ 482 P+ H + V K+HG V G P V++ E E L + Sbjct: 40 PIVGNLHQLQGMVHRCLHELSKKHGPVMHLQLGFVPLVLISSSEAAEEALKTHDIECCTR 99 Query: 483 RSTRIGRLLANGLAN----HEGEKWAKHRRI-LNPAFHHEKIKRMLPVFSACCEEMITRW 647 +T R+ + N ++W + R++ + F +K++ V M+ + Sbjct: 100 PNTNAARVFSRNNKNIGLGAYSDEWRELRKVAVREYFSVKKVQSFRYVREEENHLMVKKL 159 Query: 648 ENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGM-----KIFQLQGELSERLIQA 812 + Q VD+ L + R FG +F + KI +L E + L Sbjct: 160 RDLALKQS--PVDLSKTLFCLAASTVFRPVFGQSFSDNKHFSEEKIEELVFEAQKSLTFK 217 Query: 813 FQTLF-IPGY-WF--FPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXX 980 F LF IPG WF F + ++ + + E+ L +I ++ + Sbjct: 218 FSDLFPIPGLGWFIGFVSGQHKGLHKVFIEVDNFLNHMIDDHQKQNQPQDRSDIVGSLLD 277 Query: 981 XXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREE 1160 N +Q + L+I+ + + + AG++T+++ + W + L +P +K ++E Sbjct: 278 MIHNQEQDK---SFKLTIDHLKGITQDIFLAGIDTSAITMIWAMAELVNNPRVMKKVQDE 334 Query: 1161 VLHYFG--RTTPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPAGV 1331 + G + + E + +L+ + ++ E LRL+P L R T +++ G P Sbjct: 335 IRSCIGIKKERIEEEDVGKLQYLKLVIKETLRLHPAAPLLLPRETMADIKIQGYDIPRKT 394 Query: 1332 NLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQ 1511 L++ + DP W K+ EFNPERF D + F PFG G R C G A+ Sbjct: 395 LLLVSAWSLGRDPKYW-KNPEEFNPERFIDCPVDYKGHSFEFLPFGSGRRFCPGMASAIA 453 Query: 1512 EAKMALSTILQRFSFEL 1562 ++ L +L F ++L Sbjct: 454 TIELTLLNLLYFFDWKL 470
>O81970:C71A9_SOYBN Cytochrome P450 71A9 - Glycine max (Soybean)| Length = 499 Score = 97.8 bits (242), Expect = 1e-19 Identities = 110/468 (23%), Positives = 186/468 (39%), Gaps = 29/468 (6%) Frame = +3 Query: 246 LFTGDIPENSRFNAEARSQPMPPGSHHIAPRVLPMFTNAIK--------------EHGKV 383 LFT + + R + + +PPG PR LP N + +HG + Sbjct: 13 LFTLSLVKQLRKPTAEKRRLLPPG-----PRKLPFIGNLHQLGTLPHQSLQYLSNKHGPL 67 Query: 384 SFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANH---EGEKWAKH 554 F G P ++V E+ REI N F + S L G GE W + Sbjct: 68 MFLQLGSIPTLVVSSAEMAREIFKNHDSVFSGRPSLYAANRLGYGSTVSFAPYGEYWREM 127 Query: 555 RRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRT 734 R+I+ KR+ + EE+ + + G V++ +LT +++ R Sbjct: 128 RKIM--ILELLSPKRVQSFEAVRFEEVKLLLQTIALSHG--PVNLSELTLSLTNNIVCRI 183 Query: 735 AFGSNFQEGM----KIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMI 902 A G + G K+ ++ E L F F P + + ++ + I Sbjct: 184 ALGKRNRSGADDANKVSEMLKETQAMLGGFFPVDFFPRLGWL-----NKFSGLENRLEKI 238 Query: 903 LRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQ------QSNGKANLGLSIEDIIQECKLF 1064 R + ++ IK ++ Q + + ++ + I Sbjct: 239 FREMDNFYDQVIKEHIADNSSERSGAEHEDVVDVLLRVQKDPNQAIAITDDQIKGVLVDI 298 Query: 1065 YFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRLKIVTMIFYE 1241 + AG +T S + W + L +P+ ++A+EEV G+ + LS+L + + E Sbjct: 299 FVAGTDTASATIIWIMSELIRNPKAMKRAQEEVRDLVTGKEMVEEIDLSKLLYIKSVVKE 358 Query: 1242 VLRLYPPITFLT-RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFA 1418 VLRL+PP L R + + G + PA +++ I DP W ++ EF PERF Sbjct: 359 VLRLHPPAPLLVPREITENCTIKGFEIPAKTRVLVNAKSIAMDPCCW-ENPNEFLPERFL 417 Query: 1419 DGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + + PFG G R C G NFA+ ++AL+ +L RF +EL Sbjct: 418 VSPIDFKGQHFEMLPFGVGRRGCPGVNFAMPVVELALANLLFRFDWEL 465
>Q9STK7:C71AQ_ARATH Cytochrome P450 71A26 - Arabidopsis thaliana (Mouse-ear cress)| Length = 489 Score = 97.4 bits (241), Expect = 2e-19 Identities = 99/440 (22%), Positives = 173/440 (39%), Gaps = 19/440 (4%) Frame = +3 Query: 303 PMPPGS------HHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKF 464 P PPG H + + +G + FG P ++V EL R++L Sbjct: 33 PSPPGLPLIGNLHQLGRHPHRSLCSLSHRYGPLMLLHFGRVPVLVVSSAELARDVLKTHD 92 Query: 465 GHFGKQRSTRIGRLLANGLANHE------GEKWAKHRRILNPAFHHEKIKRMLPVFSACC 626 F + ++I L H+ GE W R++ + H +M+ F Sbjct: 93 RVFASRPRSKIFEKLLYD--KHDVASAPYGEYW---RQMKSVCVLHLFSNKMVRSFREVR 147 Query: 627 EEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLI 806 EE I+ + V++ +LT DVI + A G + G F+ EL ERL Sbjct: 148 EEEISLMMEKIRKSISLPVNLSKILVSLTNDVICKVALGRKYG-GETDFK---ELMERLN 203 Query: 807 QAFQTLFIPGY-----WFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXX 971 + T + Y W +R +D ++ + ER +++ Sbjct: 204 KLLGTFSVGSYVPWLAWI------DWIRGLDCQLEKTANDVDKFFERVVQDHVDGNRDMT 257 Query: 972 XXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKA 1151 Q + ++ I + G +T+S L+ W + L HP+ ++ Sbjct: 258 DFVDVLLAIQRDKTVGFEINRVSIKAIVMNVFVGGTDTSSTLMEWAMTELLRHPKCLKRL 317 Query: 1152 REEVLHYF-GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPA 1325 +EEV +++ E + + + + E LRL+PP+ + + + + LG PA Sbjct: 318 QEEVRTICKDKSSVSEEEIQNMSYLKAVIKEALRLHPPLPLMVPHESTQDVRLGDHHIPA 377 Query: 1326 GVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFA 1505 G +++ I + WG D EF PER D + + PFG G RIC +FA Sbjct: 378 GTQVLINAWAIGREAATWGPDVEEFRPERHLDSSVDYRGQAFELIPFGSGRRICPAISFA 437 Query: 1506 LQEAKMALSTILQRFSFELS 1565 + ++ L+ ++ RF + LS Sbjct: 438 VVLNEVVLANLVHRFDWRLS 457
>Q29488:CP2DH_MACFA Cytochrome P450 2D17 - Macaca fascicularis (Crab eating macaque)| (Cynomolgus monkey) Length = 497 Score = 97.1 bits (240), Expect = 2e-19 Identities = 58/194 (29%), Positives = 96/194 (49%), Gaps = 2/194 (1%) Frame = +3 Query: 987 SNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVL 1166 + M+++ G + E++ + AGM TTS L W L+++ +HP+ Q + ++E+ Sbjct: 277 AEMEKAKGNPESSFNEENLRMVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEID 336 Query: 1167 HYFGRTT-PDFESLSRLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLM 1340 G+ P+ +R+ T + +EV R + +T T + +EL G P G L Sbjct: 337 DVIGQVRRPEMGDQARMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIELQGFLIPKGTTLF 396 Query: 1341 LPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAK 1520 + + D +W K R F+PE F D + K P AF PF G R C+G+ A E Sbjct: 397 TNLSSVLKDEAVWEKPFR-FHPEHFLDAQGHFVK-PEAFLPFSAGRRACLGEPLARMELF 454 Query: 1521 MALSTILQRFSFEL 1562 + + +LQRFSF + Sbjct: 455 LFFTCLLQRFSFSV 468
>P12938:CP2D3_RAT Cytochrome P450 2D3 - Rattus norvegicus (Rat)| Length = 500 Score = 97.1 bits (240), Expect = 2e-19 Identities = 60/193 (31%), Positives = 96/193 (49%), Gaps = 2/193 (1%) Frame = +3 Query: 990 NMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLH 1169 N + S ANL L + D+ + AGM TTS+ LTW L+++ +HP+ Q + ++E+ Sbjct: 288 NPESSFNDANLRLVVNDL-------FGAGMVTTSITLTWALLLMILHPDVQCRVQQEIDE 340 Query: 1170 YFGRTT-PDFESLSRLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLML 1343 G+ P+ + + + +EV R + L +T + +E+ G P G L+ Sbjct: 341 VIGQVRHPEMADQAHMPFTNAVIHEVQRFADIVPMNLPHKTSRDIEVQGFLIPKGTTLIP 400 Query: 1344 PILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKM 1523 + + D +W K R F+PE F D N K AF PF G R C+G+ A E + Sbjct: 401 NLSSVLKDETVWEKPLR-FHPEHFLDAQGNFVKH-EAFMPFSAGRRACLGEPLARMELFL 458 Query: 1524 ALSTILQRFSFEL 1562 + +LQRFSF + Sbjct: 459 FFTCLLQRFSFSV 471
>Q9N0U7:CP17A_CAPHI Cytochrome P450 17A1 - Capra hircus (Goat)| Length = 509 Score = 97.1 bits (240), Expect = 2e-19 Identities = 111/472 (23%), Positives = 196/472 (41%), Gaps = 33/472 (6%) Frame = +3 Query: 294 RSQPMPP--GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSN 458 RS P P GS PR N K ++G + G VM+ +L RE+L Sbjct: 29 RSLPSLPLVGSLLFLPRRGQQHENFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLK 88 Query: 459 KFGHF-GKQRSTRIGRLLAN----GLANHEGEKWAKHRRILNPAFH-----HEKIKRML- 605 K F G+ + + L N A+H G W HR+++ AF + K+++++ Sbjct: 89 KGKEFSGRPKVATLDILSDNQKGIAFADH-GAHWQLHRKLVLNAFALFKDGNLKLEKIIN 147 Query: 606 PVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQE---GMKIFQ 776 + C+ + T+ S +D+ ++IS F +F+ +K Q Sbjct: 148 QEANVLCDFLATQHGQS--------IDLSEPLSLAVTNIISFICFNFSFKNEDPALKAIQ 199 Query: 777 -LQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXX 953 + + E L + P FP+K +M+ +L I+ K + + Sbjct: 200 NVNDGILEVLSKEILLDIFPALKIFPSKAMEKMKGCVETRNELLNEILEKCQENFTSDSI 259 Query: 954 XXXXXXXXXXXSNMQQSNGKANLG---LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLS 1124 N +N + LS ++ + AG+ETT+ ++ W + L Sbjct: 260 TNLLHILMQAKVNADNNNAGPDQDSKLLSNRHMLATIADIFGAGVETTTSVIKWIVAYLL 319 Query: 1125 MHPEWQEKAREEVLHYFG-RTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAM- 1298 HP +++ ++ + G TP + L ++ EVLR+ P L +KA+ Sbjct: 320 HHPSLKKRIQDSIDQNIGFNRTPTISDRNCLVLLEATIREVLRIRPVAPMLI--PHKAII 377 Query: 1299 --ELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFG 1469 +G + G ++++ + +HH+ W + F PERF D P+ ++ PFG Sbjct: 378 DSSIGDLTIDKGTDVVVNLWALHHNEKEW-QQPDLFMPERFLDPTGTQLISPSLSYLPFG 436 Query: 1470 GGPRICIGQNFALQEAKMALSTILQRFSFELS-----PSYIHAPYTVITLQP 1610 GPR C+G+ A QE + +S +LQRF+ E+ PS P V+ ++P Sbjct: 437 AGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDDGKLPSLEGNPSLVLQIKP 488
>P05185:CP17A_BOVIN Cytochrome P450 17A1 - Bos taurus (Bovine)| Length = 509 Score = 97.1 bits (240), Expect = 2e-19 Identities = 107/454 (23%), Positives = 189/454 (41%), Gaps = 31/454 (6%) Frame = +3 Query: 294 RSQPMPP--GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSN 458 RS P P GS PR N K ++G + G VM+ +L RE+L Sbjct: 29 RSLPSLPLVGSLPFLPRRGQQHKNFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLK 88 Query: 459 KFGHF-GKQRSTRIGRLLAN----GLANHEGEKWAKHRRILNPAFH-----HEKIKRML- 605 K F G+ + + L N A+H G W HR++ AF + K+++++ Sbjct: 89 KGKEFSGRPKVATLDILSDNQKGIAFADH-GAHWQLHRKLALNAFALFKDGNLKLEKIIN 147 Query: 606 PVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQE---GMKIFQ 776 + C+ + T+ + +D+ ++IS F +F+ +K Q Sbjct: 148 QEANVLCDFLATQHGEA--------IDLSEPLSLAVTNIISFICFNFSFKNEDPALKAIQ 199 Query: 777 ------LQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAI 938 L+ E L+ F L I FP+K +M+ + +L I+ K + Sbjct: 200 NVNDGILEVLSKEVLLDIFPVLKI-----FPSKAMEKMKGCVQTRNELLNEILEKCQENF 254 Query: 939 KNXXXXXXXXXXXXXXSNMQQSNGKANLG---LSIEDIIQECKLFYFAGMETTSVLLTWT 1109 + N +N + LS ++ + AG+ETT+ ++ W Sbjct: 255 SSDSITNLLHILIQAKVNADNNNAGPDQDSKLLSNRHMLATIGDIFGAGVETTTSVIKWI 314 Query: 1110 LIVLSMHPEWQEKAREEVLHYFG-RTTPDFESLSRLKIVTMIFYEVLRLYPPI-TFLTRR 1283 + L HP +++ ++++ G TP +RL ++ EVLR+ P T + + Sbjct: 315 VAYLLHHPSLKKRIQDDIDQIIGFNRTPTISDRNRLVLLEATIREVLRIRPVAPTLIPHK 374 Query: 1284 TYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFF 1460 +G + G ++++ + +HH W + F PERF D P+ ++ Sbjct: 375 AVIDSSIGDLTIDKGTDVVVNLWALHHSEKEW-QHPDLFMPERFLDPTGTQLISPSLSYL 433 Query: 1461 PFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 PFG GPR C+G+ A QE + +S +LQRF+ E+ Sbjct: 434 PFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEI 467
>Q9GMC7:CP17A_BISBI Cytochrome P450 17A1 - Bison bison (American bison)| Length = 509 Score = 97.1 bits (240), Expect = 2e-19 Identities = 107/454 (23%), Positives = 189/454 (41%), Gaps = 31/454 (6%) Frame = +3 Query: 294 RSQPMPP--GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSN 458 RS P P GS PR N K ++G + G VM+ +L RE+L Sbjct: 29 RSLPSLPLVGSLPFLPRRGQQHKNFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLK 88 Query: 459 KFGHF-GKQRSTRIGRLLAN----GLANHEGEKWAKHRRILNPAFH-----HEKIKRML- 605 K F G+ + + L N A+H G W HR++ AF + K+++++ Sbjct: 89 KGKEFSGRPKVATLDILSDNQKGIAFADH-GAHWQLHRKLALNAFALFKDGNLKLEKIIN 147 Query: 606 PVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQE---GMKIFQ 776 + C+ + T+ + +D+ ++IS F +F+ +K Q Sbjct: 148 QEANVLCDFLATQHGEA--------IDLSEPLSLAVTNIISFICFNFSFKNEDPALKAIQ 199 Query: 777 ------LQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAI 938 L+ E L+ F L I FP+K +M+ + +L I+ K + Sbjct: 200 NVNDGILEVLSKEVLLDIFPVLKI-----FPSKAMEKMKGYVQTRNELLNEILEKCQENF 254 Query: 939 KNXXXXXXXXXXXXXXSNMQQSNGKANLG---LSIEDIIQECKLFYFAGMETTSVLLTWT 1109 + N +N + LS ++ + AG+ETT+ ++ W Sbjct: 255 SSDSITNLLHILIQAKVNADNNNAGPDQDSKLLSSRHMLATIGDIFGAGVETTTSVIKWI 314 Query: 1110 LIVLSMHPEWQEKAREEVLHYFG-RTTPDFESLSRLKIVTMIFYEVLRLYPPI-TFLTRR 1283 + L HP +++ ++++ G TP +RL ++ EVLR+ P T + + Sbjct: 315 VAYLLHHPSLKKRIQDDIDQIIGFNRTPAISDRNRLVLLEATIREVLRIRPVAPTLIPHK 374 Query: 1284 TYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFF 1460 +G + G ++++ + +HH W + F PERF D P+ ++ Sbjct: 375 AVIDSSIGDLTIDKGTDVVVNLWALHHSEKEW-QHPDLFMPERFLDPTGTQLISPSLSYL 433 Query: 1461 PFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 PFG GPR C+G+ A QE + +S +LQRF+ E+ Sbjct: 434 PFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEI 467
>O48922:C98A2_SOYBN Cytochrome P450 98A2 - Glycine max (Soybean)| Length = 509 Score = 97.1 bits (240), Expect = 2e-19 Identities = 103/440 (23%), Positives = 176/440 (40%), Gaps = 21/440 (4%) Frame = +3 Query: 294 RSQPMPPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF 473 R P+ + I P F + +G + WFG T V+V + EL +E+L Sbjct: 33 RPWPVVGNLYDIKPVRFRCFAEWAQSYGPIISVWFGSTLNVIVSNSELAKEVLKEHDQLL 92 Query: 474 G-KQRSTRIGRLLANG---LANHEGEKWAKHRRILN-PAFHHEKIKRMLPVFSACCEEMI 638 + RS + +G + G + K R++ F ++++ + P+ M+ Sbjct: 93 ADRHRSRSAAKFSRDGKDLIWADYGPHYVKVRKVCTLELFSPKRLEALRPIREDEVTSMV 152 Query: 639 TR-WENSMSAQGLCEVDVCPEFQNLTG-DVISRTAFGSNFQEGMKIFQLQGELSERLIQA 812 + + S + L + + + + + I+R AFG F + QG + +++ Sbjct: 153 DSVYNHCTSTENLGKGILLRKHLGVVAFNNITRLAFGKRFVNSEGVMDEQGVEFKAIVEN 212 Query: 813 FQTL--------FIPGY-WFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXX 965 L IP W FP + + R R+ + E K+ Sbjct: 213 GLKLGASLAMAEHIPWLRWMFPLEEGAFAKHGARRDRLTRAIMAEHTEARKKSGGAKQHF 272 Query: 966 XXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQE 1145 + + +GL + D+I AGM+TT++ + W + L +P Q+ Sbjct: 273 VDALLTLQDKYDLSEDTIIGL-LWDMIT-------AGMDTTAISVEWAMAELIRNPRVQQ 324 Query: 1146 KAREEVLHYFG----RTTPDFESLSRLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGG 1310 K +EE+ G T DF +L L+ VT E +RL+PP L R +++GG Sbjct: 325 KVQEELDRVIGLERVMTEADFSNLPYLQCVTK---EAMRLHPPTPLMLPHRANANVKVGG 381 Query: 1311 IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICI 1490 P G N+ + + + DP +W KD EF PERF + + PFG G R+C Sbjct: 382 YDIPKGSNVHVNVWAVARDPAVW-KDPLEFRPERFLEEDVDMKGHDFRLLPFGSGRRVCP 440 Query: 1491 GQNFALQEAKMALSTILQRF 1550 G + A L +L F Sbjct: 441 GAQLGINLAASMLGHLLHHF 460
>Q9STK8:C71AP_ARATH Cytochrome P450 71A25 - Arabidopsis thaliana (Mouse-ear cress)| Length = 490 Score = 97.1 bits (240), Expect = 2e-19 Identities = 101/439 (23%), Positives = 179/439 (40%), Gaps = 14/439 (3%) Frame = +3 Query: 288 EARSQPMPPGS------HHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREI 449 + ++ P PPG H + + + +G + G P ++V ++ +EI Sbjct: 27 KGKTPPSPPGLPLIGNLHQLGRHTHRSLCDLSRRYGPLMLLHLGRVPVLIVSSADMAQEI 86 Query: 450 LSNKFGHFGKQRSTRIG-RLLANG---LANHEGEKWAKHRRILNPAFHHEKIKRMLPVFS 617 L F + +++ +LL N + GE W R++ + H +M+ F Sbjct: 87 LKTHDQAFANRPRSKLSQKLLYNNRDVASAPYGEYW---RQMKSVCVIHLLSNKMVRSFR 143 Query: 618 ACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSE 797 EE IT + +V + LT DVI R A G + +L LSE Sbjct: 144 DVREEEITLMMAKIRKSSSLPFNVSKVLECLTNDVICRVALGRKYGGETDFKKLTDRLSE 203 Query: 798 RLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXX 977 L F+P + +R D ++ + + + E+ +++ Sbjct: 204 LLGTFSIGSFVPWLAWVDW-----IRGWDAQLDKMGKDLDDFFEKVVQDHEDGDRRDGTD 258 Query: 978 XXXSNMQQSNGKANLGLSIEDI-IQECKLFYFAGMETTS-VLLTWTLIVLSMHPEWQEKA 1151 + ++ K+ G IE + I+ L F G TS LL W + L HP+ + Sbjct: 259 LIDALLRVKREKSP-GFEIERVSIKAITLDVFVGGSDTSFTLLEWAMTELLRHPKSLNRL 317 Query: 1152 REEVLHYF-GRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPA 1325 +EEV G++ + + +K + + E LRL+PP + + + ++L PA Sbjct: 318 QEEVRTICKGKSRVSEDDIQGMKYLKAVIKEALRLHPPFPMMAPHESTEDVKLRDYHIPA 377 Query: 1326 GVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFA 1505 G +M+ I + WG DA EF PER D + + PFG G RIC +FA Sbjct: 378 GTQVMMNAWAIGREVATWGPDAEEFKPERHLDTSVDFRGQNFELLPFGAGRRICPAVSFA 437 Query: 1506 LQEAKMALSTILQRFSFEL 1562 + ++ L+ ++ F ++L Sbjct: 438 VVLNEVVLANLVHGFDWKL 456
>P29980:CPXN_ANASP Probable cytochrome P450 110 - Anabaena sp. (strain PCC 7120)| Length = 459 Score = 96.7 bits (239), Expect = 3e-19 Identities = 100/433 (23%), Positives = 188/433 (43%), Gaps = 12/433 (2%) Frame = +3 Query: 366 KEHGKV-SFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLAN--GLANHEG 536 K++G + S G V++ +P+ ++EI + F R + L L +G Sbjct: 33 KKYGNIFSMQLAGIGSFVILGEPQALQEIFTQD-SRFDVGRGNTLAEPLIGRTSLMLMDG 91 Query: 537 EKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTG 716 ++ + R++L P FH E+++ ++ + W+ + Q L+ Sbjct: 92 DRHRRERKLLMPPFHGERLQAYAQQICLITNQIASEWQIGQPFVARSAM------QKLSL 145 Query: 717 DVISRTAFG----SNFQEGMKIFQLQGELSERLIQAFQTLFIPGY---WFFPTKNNRRMR 875 +VI + FG +Q+ +F +++ +++ LF+ W T + M+ Sbjct: 146 EVIIQIVFGLADGERYQQIKPLFTDWLNMTDSPLRS-SMLFLKSLQKDWGTWTPWGQ-MK 203 Query: 876 AIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQEC 1055 R I +L+ I +K R +N S M + + ++ E++ E Sbjct: 204 HKQRSIYDLLQAEIEEK-RTKENEQRGDVL-------SLMMAARDENGQAMTDEELKDEL 255 Query: 1056 KLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTPDFESLSRLKIVTMIF 1235 FAG ETT+ + W + + QEK ++E L G P+ +++L +T + Sbjct: 256 LTILFAGHETTATTIAWAFYQILKNVNVQEKLQQE-LDRLG-ANPNPMEIAQLPYLTAVS 313 Query: 1236 YEVLRLYPPI-TFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 E LR+YP + T R T ++ + G + LM I IH+ D++ + ++F PER Sbjct: 314 QETLRMYPVLPTLFPRITKSSINIAGYQLEPDTTLMASIYLIHYREDLY-PNPQQFRPER 372 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSY-IHAPY 1589 F + P+ + PFGGG R C+G AL E K+ ++T+L + L+ ++ Sbjct: 373 FIE----RQYSPSEYIPFGGGSRRCLGYALALLEIKLVIATVLSNYQLALAEDKPVNVQR 428 Query: 1590 TVITLQPQHGAQI 1628 TL P G ++ Sbjct: 429 RGFTLAPDGGVRV 441
>O81974:C71D8_SOYBN Cytochrome P450 71D8 - Glycine max (Soybean)| Length = 504 Score = 96.7 bits (239), Expect = 3e-19 Identities = 87/416 (20%), Positives = 167/416 (40%), Gaps = 16/416 (3%) Frame = +3 Query: 363 IKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLANHE--- 533 ++++G + G ++V P++ E++ HF ++ + + G + Sbjct: 64 VRKYGPLMHLQLGEISTLVVSSPKMAMEMMKTHDVHFVQRPQLLAPQFMVYGATDIAFAP 123 Query: 534 -GEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNL 710 G+ W + R+I K + FS ++ + S+ + +D+ + +L Sbjct: 124 YGDYWRQIRKICTLELLSAK---RVQSFSHIRQDENKKLIQSIHSSAGSPIDLSGKLFSL 180 Query: 711 TGDVISRTAFGSNFQEGMKIFQLQ--------GELSERLIQAFQTLFIPGYWFFPTKNNR 866 G +SR AFG + + L G + + + + L + T+ Sbjct: 181 LGTTVSRAAFGKENDDQDEFMSLVRKAITMTGGFEVDDMFPSLKPLHLL------TRQKA 234 Query: 867 RMRAIDREIRMILRGIIGK---KERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIE 1037 ++ + + IL I+ K K +K + +G + +++E Sbjct: 235 KVEHVHQRADKILEDILRKHMEKRTRVKEGNGSEAEQEDLVDVLLRLKESGSLEVPMTME 294 Query: 1038 DIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYF-GRTTPDFESLSRL 1214 +I + AG +T++ L W + + +P+ +EKA+ E+ F G+ L L Sbjct: 295 NIKAVIWNIFAAGTDTSASTLEWAMSEMMKNPKVKEKAQAELRQIFKGKEIIRETDLEEL 354 Query: 1215 KIVTMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAR 1394 + + E LRL+PP + R + + G + P +M+ I DP W DA Sbjct: 355 SYLKSVIKETLRLHPPSQLIPRECIISTNIDGYEIPIKTKVMINTWAIGRDPQYWS-DAD 413 Query: 1395 EFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 F PERF D + + PFG G R+C G F L + L+ +L F++EL Sbjct: 414 RFIPERFNDSSIDFKGNSFEYIPFGAGRRMCPGMTFGLASITLPLALLLYHFNWEL 469
>Q92109:CP1A3_ONCMY Cytochrome P450 1A3 - Oncorhynchus mykiss (Rainbow trout) (Salmo| gairdneri) Length = 522 Score = 96.3 bits (238), Expect = 4e-19 Identities = 101/470 (21%), Positives = 182/470 (38%), Gaps = 34/470 (7%) Frame = +3 Query: 333 PRVLPMFTNAIKEH--------------GKVSFTWFGPTPRVMVPDPELVREILSNKFGH 470 P+ LP+ N ++ H G V G P V++ E VR+ L + Sbjct: 48 PKPLPIIGNMLEVHNNPHLSLTAMSERYGSVFQIQIGMRPVVVLSGNETVRQALIKQGED 107 Query: 471 FGKQRSTRIGRLLANG----LANHEGEKWAKHRRILNPAFHH-EKIKRMLPVFSACCEEM 635 F + + + +G + + W R++ A ++ P +S EE Sbjct: 108 FAGRSDLYSFKFINDGKSLAFSTDKAGVWRARRKLAMSALRSFATLEGTTPEYSCALEEH 167 Query: 636 ITRWENSMSAQGLCEVDVCPEFQNL------TGDVISRTAFGSNF----QEGMKIFQLQG 785 + + + Q +DV F +VI FG + QE + + + Sbjct: 168 VLKEGEYLVKQLTSVMDVSGSFDPFRHIVVSVANVICGMCFGRRYSHDDQELLGLVNMSD 227 Query: 786 ELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXX 965 E + + FIP + P + +R I+ ++ I+ + + Sbjct: 228 EFGQVVGSGNPADFIPILRYLPNRTMKRFMDINDRFNNFVQKIVSEHYESYDKDNIRDIT 287 Query: 966 XXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQE 1145 + ++ + AN+ +S E I+ + AG +T S L+W ++ L +PE QE Sbjct: 288 DSLIDHCED-RKLDENANIQVSDEKIVGIVNDLFGAGFDTISTALSWAVVYLVAYPETQE 346 Query: 1146 KAREEVLHYFGR-TTPDFESLSRLKIVTMIFYEVLR--LYPPITFLTRRTYKAMELGGIK 1316 + +E+ G TP L ++ E+ R + P T + T K L G Sbjct: 347 RLHQELKEKVGMIRTPRLSDKINLPLLEAFILEIFRHSSFLPFT-IPHCTIKDTSLNGYF 405 Query: 1317 YPAGVNLMLPILFIHHDPDIWGKDAREFNPERF--ADGISNAAKRPAAFFPFGGGPRICI 1490 P + + ++HDP++W K+ FNP+RF ADG FG G R CI Sbjct: 406 IPKDTCVFINQWQVNHDPELW-KEPSSFNPDRFLSADGTELNKLEGEKVLVFGMGKRRCI 464 Query: 1491 GQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQPQHGAQIRLKK 1640 G+ E + L+ +LQR F+ P + + + P++G ++ K+ Sbjct: 465 GEAIGRNEVYLFLAILLQRLRFQEKPGH------PLDMTPEYGLTMKHKR 508
>Q8HYN0:CP17A_PAPCY Cytochrome P450 17A1 - Papio cynocephalus (Yellow baboon)| Length = 508 Score = 96.3 bits (238), Expect = 4e-19 Identities = 105/438 (23%), Positives = 187/438 (42%), Gaps = 22/438 (5%) Frame = +3 Query: 315 GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF-GKQ 482 GS PR M N K ++G + G V+V +L +E+L K F G+ Sbjct: 38 GSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRP 97 Query: 483 RSTRIGRLLAN--GLANHE-GEKWAKHRRILNPAFH-----HEKIKRMLPVFSACCEEMI 638 + T + L N G+A + G W HRR+ F +K+++++ C+E+ Sbjct: 98 QVTTLDILSNNRKGIAFADYGAHWQLHRRLAMATFALFKDGDQKLEKII------CQEIS 151 Query: 639 TRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAF- 815 T + + G P F +T +VIS F +++ G ++ +E +I + Sbjct: 152 TLCDMLATHNGQTIDISFPVFVAIT-NVISLICFNISYKNGDPELKIVHNYNEGIIDSLG 210 Query: 816 -QTL--FIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXX 986 ++L P FP K +++ + +L I + ++ Sbjct: 211 KESLVDLFPWLKVFPNKTLEKLKRHVKTRNDLLTKIFENYKEKFRSDSITNMLDVLMQAK 270 Query: 987 SNMQQSNGKANLG---LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKARE 1157 N N + LS I+ + AG+ETT+ ++ W + L +P+ ++K E Sbjct: 271 MNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWIVAFLLHNPQVKKKLYE 330 Query: 1158 EVLHYFGRT-TPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPAGV 1331 E+ G + TP +RL ++ EVLR+ P L + +G G Sbjct: 331 EIDQNVGFSRTPTISDRNRLLLLEATIREVLRIRPVAPMLIPHKANVDSSIGEFAVDKGT 390 Query: 1332 NLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNFAL 1508 ++++ + +HH+ W + +F PERF + P+ ++ PFG GPR CIG+ A Sbjct: 391 HVIINLWALHHNEKEWHQPD-QFMPERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILAR 449 Query: 1509 QEAKMALSTILQRFSFEL 1562 QE + ++ +LQRF E+ Sbjct: 450 QELFLIMAWLLQRFDLEV 467
>O22307:C71DB_LOTJA Cytochrome P450 71D11 - Lotus japonicus| Length = 490 Score = 96.3 bits (238), Expect = 4e-19 Identities = 96/413 (23%), Positives = 171/413 (41%), Gaps = 14/413 (3%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLAN----HE 533 K++G + G ++V E +E++ F + + ++ G + Sbjct: 49 KKYGPLMHLQLGEVIFIIVSSAEYAKEVMKTHDVTFASRPRSLFTDIVFYGSTDIGFSPY 108 Query: 534 GEKWAKHRRILN-PAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNL 710 G+ W + R+I N ++++ + P+ + +I R ++++ V++ +L Sbjct: 109 GDYWRQVRKICNVELLSMKRVQSLWPIREEEVKNLIQR----IASEEGSVVNLSQAIDSL 164 Query: 711 TGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQT--LFIPGYWFFPTKNNRRMRA-- 878 + SR+AFG + E + E+ +L F LF W +N RMR+ Sbjct: 165 IFTITSRSAFGKRYMEQEEFISCVREVM-KLAGGFNIADLFPSAKWL---ENLTRMRSKF 220 Query: 879 --IDREIRMILRGIIG--KKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDII 1046 + +++ IL II K K + S+ + L+I +I Sbjct: 221 EYLHQKMDRILETIIDDHKANSRTKEGQVEGGEEDLIDVLLKYENSSTDQDFHLTIRNIK 280 Query: 1047 QECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP-DFESLSRLKIV 1223 + AG ET++ + WT+ + P +KA++EV F R D + LK + Sbjct: 281 AILFDIFIAGSETSATTINWTMAEMMKDPILLKKAQDEVREIFQRRGKVDETCIYELKYL 340 Query: 1224 TMIFYEVLRLYPPITFLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFN 1403 EVLRL+PP + R +A E+ G PA +++ I D W + R F Sbjct: 341 KAFINEVLRLHPPGPLVFRECRQACEINGYHIPAKSTVLVNTFAIGTDSKYWAEPER-FC 399 Query: 1404 PERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 PERF D + PFG G RIC G N+ + ++ L+ +L F + L Sbjct: 400 PERFIDSSIDYKGTNFEHLPFGAGRRICPGINYGMANVELVLALLLYHFDWTL 452
>Q9LVD2:C71BA_ARATH Cytochrome P450 71B10 - Arabidopsis thaliana (Mouse-ear cress)| Length = 502 Score = 96.3 bits (238), Expect = 4e-19 Identities = 106/465 (22%), Positives = 180/465 (38%), Gaps = 42/465 (9%) Frame = +3 Query: 294 RSQPMPPGS------HHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILS 455 R P PPG H + K++G V G P V+V PE +++L Sbjct: 29 RQPPSPPGLPIIGNLHQLGELPHQSLCKLSKKYGPVMLLKLGRVPTVIVSTPETAKQVLK 88 Query: 456 NKFGHFGKQRSTRIGRLLANGLAN----HEGEKWAKHRRI-LNPAFHHEKIKRMLPVFSA 620 + H + S R L+ + + W + R++ + F +++I + P+ A Sbjct: 89 DYDLHCCSRPSLEGTRKLSYNYLDIAFSRFDDYWKELRKLCVEELFCNKRINSIQPIKEA 148 Query: 621 CCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGM----KIFQLQGE 788 E++I S S + L V++ F +L +VI + FG NFQ + K L E Sbjct: 149 EMEKLIDSIAESASQKTL--VNLSDTFLSLNVNVICKAVFGVNFQGTVLNNDKFQDLVHE 206 Query: 789 LSERLIQAFQTLFIP--GY---WFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXX 953 E L + F P G+ WF G+ ++ER++++ Sbjct: 207 ALEMLGSFSASDFFPYVGWIVDWF--------------------TGLHARRERSVRDLDA 246 Query: 954 XXXXXXXXXXXSNMQQSNGK-ANLGLSIEDIIQECKLFY----------------FAGME 1082 N ++S +L L +E +E L Y G+ Sbjct: 247 FYEQMIDLHLQKNREESEDDFVDLLLRLEK--EEAVLGYGKLTRNHIKAILMNILLGGIN 304 Query: 1083 TTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP----DFESLSRLKIVTMIFYEVLR 1250 T+++ +TW + L +P +K + E+ G+ + ++ L + M+ E R Sbjct: 305 TSAITMTWAMAELIRNPRVMKKVQSEIRAQIGKNNKTRIISLDEINHLSYLNMVIKETCR 364 Query: 1251 LYPPITFLT-RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGI 1427 L+P L R ++ G L + + I DP+IW KD EF PERF D Sbjct: 365 LHPVAPLLVPREVISEFKINGYTIQPKTRLHVNVWAIGRDPEIW-KDPEEFLPERFMDCD 423 Query: 1428 SNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 + + PFG G RIC + + L+ +L F ++L Sbjct: 424 IDVKGQDYELLPFGSGRRICPAVYMGITTVEFGLANLLYHFDWKL 468
>Q9SAE1:C71BR_ARATH Cytochrome P450 71B27 - Arabidopsis thaliana (Mouse-ear cress)| Length = 503 Score = 95.9 bits (237), Expect = 5e-19 Identities = 105/452 (23%), Positives = 185/452 (40%), Gaps = 20/452 (4%) Frame = +3 Query: 267 ENSRFNAEAR--SQPMPPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELV 440 +N++FN S P+ HH+ + ++G V G P V++ E Sbjct: 25 KNTKFNLPPSPPSLPIIGNLHHLTGLPHRCYHKLSIKYGPVILLHLGFVPVVVISLSEAA 84 Query: 441 REIL-SNKFGHFGKQRSTRIGRLLANGLANHE----GEKWAKHRRI-LNPAFHHEKIKRM 602 +L ++ + ++ G+L + G + E W + R++ + F +K++ Sbjct: 85 EAVLKTHDLECCSRPKTVGTGKL-SYGFKDISFVPYSEYWREMRKLAVTELFSLKKVQSY 143 Query: 603 LPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQ 782 + E M+ + S Q VD+ F +LT +I R A G NF E I + Sbjct: 144 RYIRGEEIEFMVKKLSESALKQS--PVDLGSTFFSLTASIIFRVALGRNFHESGSIIDQE 201 Query: 783 GELSERLIQAFQTLFIPGYW--FFPTKNNRRMRAIDR---EIRMILRGIIGKKERAIKNX 947 G E L+ A T + FFP+ R + + R I + + + I + Sbjct: 202 G--IEELVTAATTAIGSFTFSDFFPSGLGRFLDCLFRTQTNINKVSEKLDAFYQHVIDDH 259 Query: 948 XXXXXXXXXXXXXSNM----QQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLI 1115 + M ++ K + L++++I + AG++T ++ + W + Sbjct: 260 LKPSTLDSSGDIVALMLDMIKKKGHKDDFKLNVDNIKAVLMNIFLAGIDTGAITMIWAMT 319 Query: 1116 VLSMHPEWQEKAREEVLHYFG--RTTPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRT 1286 L P ++A+E + G R E L + + I E LRL+PP+ FL R T Sbjct: 320 ELVKKPLVMKRAQENIRGVLGLKRDRITEEDLCKFDCLKHIVKETLRLHPPVPFLVPRET 379 Query: 1287 YKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPF 1466 +++ G P + + + I DP W D EF PERFA+ + + F PF Sbjct: 380 ISHIKIQGYDIPPKTQIQVNVWTIGRDPKRW-TDPEEFRPERFANTCVDFRGQHFDFLPF 438 Query: 1467 GGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 G G RIC + A+ ++ L +L F + L Sbjct: 439 GSGRRICPAISMAIATVELGLMNLLDFFDWRL 470
>O42231:CP1A1_LIZAU Cytochrome P450 1A1 - Liza aurata (Golden grey mullet)| Length = 521 Score = 95.5 bits (236), Expect = 7e-19 Identities = 108/486 (22%), Positives = 189/486 (38%), Gaps = 22/486 (4%) Frame = +3 Query: 249 FTGDIPENSRFNAEARSQPMPPGSHHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPD 428 F +IPE + P+ + R T K +G V G P V++ Sbjct: 34 FQANIPEGLSRLPGPKPLPIIGNVLEVGSRPYLSLTEMSKRYGNVFQIQIGMRPVVVLSG 93 Query: 429 PELVREILSNKFGHFGKQRSTRIGRLLANG----LANHEGEKWAKHRRILNPAFHH-EKI 593 E VR+ L + F + R ++ G + + W R++ A + Sbjct: 94 NETVRQALIKQGDEFAGRPDLYSFRFISEGKSLAFSTDQAGVWRARRKLAYSALRSFSTL 153 Query: 594 KRMLPVFSACCEE--------MITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSN 749 + P +S EE +I + + M A G D +VI FG Sbjct: 154 EGTTPEYSCVLEEHISKEAEYLIKQLDTVMKADG--SFDPFRYIVVSVANVICGMCFGRR 211 Query: 750 F----QEGMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGII 917 + +E + + L E + + FIP + P K ++ I+ ++ I+ Sbjct: 212 YDHHDRELLSLVNLSDEFGQVVGSGNPADFIPILQYLPNKTMKKFVNINDRFISFVQKIV 271 Query: 918 GKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVL 1097 + A N ++ + AN+ +S E ++ + AG++T S Sbjct: 272 SE-HYATFNKDNIRDITDSLIDHCEDRKLDENANVQMSDEKVVGIVNDLFGAGLDTISTA 330 Query: 1098 LTWTLIVLSMHPEWQEKAREEVLHYFG-RTTPDFESLSRLKIVTMIFYEVLR--LYPPIT 1268 L+W+++ L +PE QE+ +E+ G TP + L ++ E+ R + P T Sbjct: 331 LSWSVMYLVAYPEIQERLYQELKENVGLDRTPVLSDRNNLPLLEAFILEIFRHSSFLPFT 390 Query: 1269 FLTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERF--ADGISNAAK 1442 + T K L G P + + I+HDP++W K+ FNP+RF ADG Sbjct: 391 -IPHCTTKDTSLNGYYIPKDTCVFINQWQINHDPELW-KEPSSFNPDRFLSADGTEVNKV 448 Query: 1443 RPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFELSPSYIHAPYTVITLQPQHGA 1622 FG G R CIG+ A E M L+ ++Q+ F + P + + P++G Sbjct: 449 DGEKVMVFGLGKRRCIGEVIARNEVYMFLAILIQKLHF------YNLPGEPLDMTPEYGL 502 Query: 1623 QIRLKK 1640 ++ K+ Sbjct: 503 TMKHKR 508
>Q8HYM9:CP17A_MACMU Cytochrome P450 17A1 - Macaca mulatta (Rhesus macaque)| Length = 508 Score = 95.5 bits (236), Expect = 7e-19 Identities = 108/440 (24%), Positives = 188/440 (42%), Gaps = 24/440 (5%) Frame = +3 Query: 315 GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF-GKQ 482 GS PR M N K ++G + G V+V +L +E+L K F G+ Sbjct: 38 GSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRP 97 Query: 483 RSTRIGRLLAN--GLANHE-GEKWAKHRRILNPAFH-----HEKIKRMLPVFSACCEEMI 638 + T + L N G+A + G W HRR+ F +K+++++ C+E+ Sbjct: 98 QVTTLDILSNNRKGIAFADYGAHWQLHRRLAMATFALFKDGDQKLEKII------CQEIS 151 Query: 639 TRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAF- 815 T + + G P F +T +VIS F +++ G ++ +E +I + Sbjct: 152 TLCDMLATHNGQTIDISFPVFVAIT-NVISLICFNISYKNGDPELKIVHNYNEGIIDSLG 210 Query: 816 -QTL--FIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXX 986 ++L P FP K +++ + +L I + K Sbjct: 211 KESLVDLFPWLKVFPNKTLEKLKRHVKTRNDLLTKIFENYKE--KFHSDSITNMLDVLMQ 268 Query: 987 SNMQQSNGKANLG-----LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKA 1151 + M NG A LS I+ + AG+ETT+ ++ W + L +P+ ++K Sbjct: 269 AKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWIVAFLLHNPQVKKKL 328 Query: 1152 REEVLHYFGRT-TPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPA 1325 EE+ G + TP +RL ++ EVLR+ P L + +G Sbjct: 329 YEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRIRPVAPMLIPHKANVDSSIGEFAVDK 388 Query: 1326 GVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNF 1502 G ++++ + +HH+ W + +F PERF + P+ ++ PFG GPR CIG+ Sbjct: 389 GTHVIINLWALHHNEKEWHQPD-QFMPERFLNPAGTQLISPSLSYLPFGAGPRSCIGEIL 447 Query: 1503 ALQEAKMALSTILQRFSFEL 1562 A QE + ++ +LQRF E+ Sbjct: 448 ARQELFLIMAWLLQRFDLEV 467
>Q2XVA1:CP17A_MACFA Cytochrome P450 17A1 - Macaca fascicularis (Crab eating macaque)| (Cynomolgus monkey) Length = 508 Score = 95.5 bits (236), Expect = 7e-19 Identities = 108/440 (24%), Positives = 188/440 (42%), Gaps = 24/440 (5%) Frame = +3 Query: 315 GSHHIAPRVLPMFTNAIK---EHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHF-GKQ 482 GS PR M N K ++G + G V+V +L +E+L K F G+ Sbjct: 38 GSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRP 97 Query: 483 RSTRIGRLLAN--GLANHE-GEKWAKHRRILNPAFH-----HEKIKRMLPVFSACCEEMI 638 + T + L N G+A + G W HRR+ F +K+++++ C+E+ Sbjct: 98 QVTTLDILSNNRKGIAFADYGAHWQLHRRLAMATFALFKDGDQKLEKII------CQEIS 151 Query: 639 TRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAF- 815 T + + G P F +T +VIS F +++ G ++ +E +I + Sbjct: 152 TLCDMLATHNGQTIDISFPVFVAIT-NVISLICFNISYKNGDPELKIVHNYNEGIIDSLG 210 Query: 816 -QTL--FIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXX 986 ++L P FP K +++ + +L I + K Sbjct: 211 KESLVDLFPWLKVFPNKTLEKLKRHVKTRNDLLTKIFENYKE--KFHSDSITNMLDVLMQ 268 Query: 987 SNMQQSNGKANLG-----LSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKA 1151 + M NG A LS I+ + AG+ETT+ ++ W + L +P+ ++K Sbjct: 269 AKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWIVAFLLHNPQVKKKL 328 Query: 1152 REEVLHYFGRT-TPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPA 1325 EE+ G + TP +RL ++ EVLR+ P L + +G Sbjct: 329 YEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRIRPVAPMLIPHKANVDSSIGEFAVDK 388 Query: 1326 GVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPA-AFFPFGGGPRICIGQNF 1502 G ++++ + +HH+ W + +F PERF + P+ ++ PFG GPR CIG+ Sbjct: 389 GTHVIINLWALHHNEKEWHQPD-QFMPERFLNPAGTQLISPSLSYLPFGAGPRSCIGEIL 447 Query: 1503 ALQEAKMALSTILQRFSFEL 1562 A QE + ++ +LQRF E+ Sbjct: 448 ARQELFLIMAWLLQRFDLEV 467
>O48923:C71DA_SOYBN Cytochrome P450 71D10 - Glycine max (Soybean)| Length = 510 Score = 95.5 bits (236), Expect = 7e-19 Identities = 95/446 (21%), Positives = 185/446 (41%), Gaps = 27/446 (6%) Frame = +3 Query: 306 MPPGSHHIAPRVLPMF----------------TNAIKEHGKVSFTWFGPTPRVMVPDPEL 437 +PPG PR LP+ N ++G + G ++V PE+ Sbjct: 43 LPPG-----PRTLPLIGNIHQIVGSLPVHYYLKNLADKYGPLMHLKLGEVSNIIVTSPEM 97 Query: 438 VREILSNKFGHFGKQRSTRIGRLLA-NG---LANHEGEKWAKHRRILN-PAFHHEKIKRM 602 +EI+ +F + + R+++ NG + + G+ W + R+I ++++ Sbjct: 98 AQEIMKTHDLNFSDRPDFVLSRIVSYNGSGIVFSQHGDYWRQLRKICTVELLTAKRVQSF 157 Query: 603 LPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTGDVISRTAFG--SNFQEGMKIFQ 776 + E++ + + S +G ++ ++T + +R AFG S +Q+ +F Sbjct: 158 RSIREEEVAELVKKIAATASEEGGSIFNLTQSIYSMTFGIAARAAFGKKSRYQQ---VFI 214 Query: 777 LQGELSERLIQAFQT--LFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXX 950 L+ F L+ F ++ + R +L+ II + + ++ Sbjct: 215 SNMHKQLMLLGGFSVADLYPSSRVFQMMGATGKLEKVHRVTDRVLQDIIDEHKNRNRSSE 274 Query: 951 XXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMH 1130 Q+ + +I+ +IQ+ + G ET+S ++ W + L + Sbjct: 275 EREAVEDLVDVLLKFQKESEFRLTDDNIKAVIQD---IFIGGGETSSSVVEWGMSELIRN 331 Query: 1131 PEWQEKAREEVLH-YFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAM-EL 1304 P E+A+ EV Y + D L +L + I E +RL+PP+ L R + ++ Sbjct: 332 PRVMEEAQAEVRRVYDSKGYVDETELHQLIYLKSIIKETMRLHPPVPLLVPRVSRERCQI 391 Query: 1305 GGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRI 1484 G + P+ +++ I +P WG + F PERF + + F PFG G RI Sbjct: 392 NGYEIPSKTRIIINAWAIGRNPKYWG-ETESFKPERFLNSSIDFRGTDFEFIPFGAGRRI 450 Query: 1485 CIGQNFALQEAKMALSTILQRFSFEL 1562 C G FA+ ++ L+ +L F ++L Sbjct: 451 CPGITFAIPNIELPLAQLLYHFDWKL 476
>Q9LIP3:C71BY_ARATH Cytochrome P450 71B37 - Arabidopsis thaliana (Mouse-ear cress)| Length = 500 Score = 95.5 bits (236), Expect = 7e-19 Identities = 109/458 (23%), Positives = 186/458 (40%), Gaps = 35/458 (7%) Frame = +3 Query: 294 RSQPMPPGS------HHIAPRVLPMFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILS 455 R P PPG H + + K++G V FG P V+V E ++ L Sbjct: 30 RKPPSPPGFPIIGNLHQLGELPHQSLWSLSKKYGPVMLLKFGSIPTVVVSSSETAKQALK 89 Query: 456 NKFGHFGKQRSTRIGRLLANG----LANHEGEKWAKHRRI-LNPAFHHEKIKRMLPVFSA 620 + + S R L+ + + + W + RR+ + F +++ + P+ Sbjct: 90 IHDLNCCSRPSLAGPRALSYNYLDIVFSPFNDYWKELRRMCVQELFSPKQVHLIQPIR-- 147 Query: 621 CCEEMITRWENSMS--AQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELS 794 EE + + NS S A V++ + +LT VI + AFG +FQ + L + Sbjct: 148 --EEEVKKLMNSFSESAAQKTPVNLSEKLASLTVGVICKAAFGVSFQGTV----LNSDNF 201 Query: 795 ERLIQ-AFQTLFIPGYW---FFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXX 962 ++LI AF LF+ + +FP I L G+ G++ER+++ Sbjct: 202 DKLIHDAF--LFLGSFSASDYFPNVG---------WIIDWLTGLQGQRERSVRGLDAFYE 250 Query: 963 XXXXXXXXSNMQQSNGKANLGLSIEDIIQECKLFY----------------FAGMETTSV 1094 N + +L L +E +E L Y G+ T+++ Sbjct: 251 QMFDLHKQGNKEGVEDFVDLLLKLEK--EETVLGYGKLTRNHIKAVLMNVLLGGIGTSAI 308 Query: 1095 LLTWTLIVLSMHPEWQEKAREEVLHYFG-RTTPDFESLSRLKIVTMIFYEVLRLYPPITF 1271 +TW + L +P +K + E+ + G ++ + + +L + M+ E RL+PP Sbjct: 309 TMTWAMTELMRNPRVMKKVQSEIRNQIGGKSMICLDDIDQLHYLKMVINETWRLHPPAPL 368 Query: 1272 LT-RRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRP 1448 L R E+ G PA L + + I DPD W KD EF PERF + +A + Sbjct: 369 LVPREVMSEFEINGYTIPAKTRLYVNVWGIGRDPDTW-KDPEEFLPERFVNSNIDAKGQN 427 Query: 1449 AAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSFEL 1562 PFG G R+C + L+ +L F ++L Sbjct: 428 FELLPFGSGRRMCPAMYMGTTMVEFGLANLLYHFDWKL 465
>Q12573:CP52W_CANAP Cytochrome P450 52E2 - Candida apicola (Yeast)| Length = 519 Score = 95.1 bits (235), Expect = 9e-19 Identities = 61/173 (35%), Positives = 84/173 (48%), Gaps = 12/173 (6%) Frame = +3 Query: 1071 AGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTT---PDFESLSRLKIVTMIFYE 1241 AG +TT+ LL++T L +PE ++ RE V+ FG P FE L + K++ + E Sbjct: 312 AGRDTTAALLSFTTYYLGAYPEVYDELREAVIADFGSADAEPPTFEQLKQCKVLQNVIRE 371 Query: 1242 VLRLYP--PITFLTRRTYKAMELGG-------IKYPAGVNLMLPILFIHHDPDIWGKDAR 1394 VLRL+P P+ F GG I P G + + + IWG D+ Sbjct: 372 VLRLHPNVPLNFREAIADTTFPTGGGPNGDQPIFVPKGQKVFYATYVMQRNAGIWGPDST 431 Query: 1395 EFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFS 1553 F P+R+ + A + PF GGPRIC+GQ FAL EA L I Q FS Sbjct: 432 SFRPDRWNEP-REALASGWDYIPFNGGPRICLGQQFALTEASYTLVRICQEFS 483 Score = 36.2 bits (82), Expect = 0.48 Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 4/141 (2%) Frame = +3 Query: 339 VLPMFTNAIKEHGK-VSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQ-RSTRIGRLLA 512 +L FT+ +E G+ +F + +PE ++ +L+ F + R + LL Sbjct: 68 LLEWFTHRFEEFGRRTAFQSVAGQLWIGTIEPENIKTMLATSFKDYSLGFRYNAMYGLLG 127 Query: 513 NGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMS--AQGLCEVD 686 NG+ G+ W R +L P F E++ + E M T ++ +G VD Sbjct: 128 NGIFTLSGDGWKNSRALLRPQFSREQVSHL--------ESMRTHINMMINNHFKGGQVVD 179 Query: 687 VCPEFQNLTGDVISRTAFGSN 749 + NLT D + FG + Sbjct: 180 AQVLYHNLTIDTATEFLFGES 200
>P30610:CP52H_CANTR Cytochrome P450 52A8 - Candida tropicalis (Yeast)| Length = 517 Score = 95.1 bits (235), Expect = 9e-19 Identities = 109/431 (25%), Positives = 176/431 (40%), Gaps = 32/431 (7%) Frame = +3 Query: 438 VREILSNKFGHFGK-QRSTRIGRLLANGLANHEGEKWAKHRRILNPAFHHEKIKRML--- 605 ++ +L+ +F F +R T LL +G+ +G+ W R +L P F E++ + Sbjct: 103 IKALLATQFSDFSLGKRHTLFKPLLGDGIFTLDGQGWKHSRAMLRPQFAREQVAHVTSLE 162 Query: 606 PVFSACCEEMITRWENSMSAQGLC---EVDVCPEF------QNLTGDVISRTAFGSNFQE 758 P F + M+ Q L VD EF +L + I +F Sbjct: 163 PHFQLLKKHMVKNKGGFFDIQELFFRFTVDSATEFLFGESVHSLKDETIGSYQDDIDFV- 221 Query: 759 GMKIFQLQGELSERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAI 938 G K F ++ + A +TL Y+ NN+ R ++ + + + A Sbjct: 222 GRKDFAESFNKAQEYL-AIRTLVQDFYYLV---NNQEFRDCNKLVHKFTNYYVQRALDAT 277 Query: 939 KNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECKL-FYFAGMETTSVLLTWTLI 1115 ++Q+ G +++++ L AG +T++ LL++ + Sbjct: 278 PEELEKQSGYVFLYEL--VKQTRGP--------NVLRDQSLNILLAGRDTSAGLLSFAVF 327 Query: 1116 VLSMHPEWQEKAREEVLHYFGRTTPD------FESLSRLKIVTMIFYEVLRLYP--PITF 1271 L+ +P K RE+V FG FESL R + E LR+YP P F Sbjct: 328 ELARNPHIWAKLREDVESQFGLGEQSRIEEITFESLKRCGYLKAFLNETLRVYPSVPRNF 387 Query: 1272 LTRRTYKAMELGG-------IKYPAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGIS 1430 + GG + G + I H DP +G DA EF PER+ + Sbjct: 388 RIATKNTTLPRGGGSDGNSPVLVKKGEAVSYGINSTHLDPVYYGDDAAEFRPERWNE--P 445 Query: 1431 NAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRF-SFELSPSYIHAP--YTVIT 1601 + K A+ PF GGPRIC+GQ FAL EA L + Q F + EL P ++ P T +T Sbjct: 446 STRKLGWAYLPFNGGPRICLGQQFALTEAGYVLVRLAQSFDTLELKPPVVYPPKRLTNLT 505 Query: 1602 LQPQHGAQIRL 1634 + Q G +++ Sbjct: 506 MSLQDGTIVKI 516
>Q9V559:CP4P3_DROME Probable cytochrome P450 4p3 - Drosophila melanogaster (Fruit fly)| Length = 515 Score = 95.1 bits (235), Expect = 9e-19 Identities = 64/203 (31%), Positives = 103/203 (50%), Gaps = 5/203 (2%) Frame = +3 Query: 1041 IIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTTP--DFESLSRL 1214 I +E F G +TTS+ L + L+ +S++PE QEK +E+ + L++L Sbjct: 312 ICEEVDTLMFEGYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANIDDELNILNIGQLNKL 371 Query: 1215 KIVTMIFYEVLRLYPPITFLTRRTYKAMELG-GIKYPAGVNLMLPILFIHHDPDIWGKDA 1391 K + E +RL+P + + R T + EL G+ P G + + + IH +P+ W Sbjct: 372 KNLEYFIKETMRLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYWDSP- 430 Query: 1392 REFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF--ELS 1565 EF PERF S + A+ PF G R CIGQ FA+QE K + +L++F E+ Sbjct: 431 EEFRPERFLPENSQN-RHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEID 489 Query: 1566 PSYIHAPYTVITLQPQHGAQIRL 1634 P I T +TL+ ++ ++L Sbjct: 490 PKTI-VFQTGLTLRTKNQIHVKL 511 Score = 32.0 bits (71), Expect = 9.1 Identities = 22/84 (26%), Positives = 38/84 (45%) Frame = +3 Query: 507 LANGLANHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVD 686 L GL G+KW R++L+P FH + + +F + + +++ + A + + Sbjct: 125 LRTGLLTSTGKKWHARRKMLSPTFHFNILNQFQEIFITESLKFLEQFKGNDEAI-ISLNE 183 Query: 687 VCPEFQNLTGDVISRTAFGSNFQE 758 V P F T + I TA G E Sbjct: 184 VIPRF---TLNSICETAMGVKLDE 204
>P51589:CP2J2_HUMAN Cytochrome P450 2J2 - Homo sapiens (Human)| Length = 502 Score = 95.1 bits (235), Expect = 9e-19 Identities = 88/408 (21%), Positives = 168/408 (41%), Gaps = 10/408 (2%) Frame = +3 Query: 363 IKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLL--ANGLANHEG 536 +K++G + G V++ L++E L + +FG + T + + NGL G Sbjct: 72 VKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSG 131 Query: 537 EKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTG 716 + W + RR A + + + +E ++ + D + N Sbjct: 132 QAWKEQRRFTLTALRNFGLGKKS--LEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVS 189 Query: 717 DVISRTAFGSNFQEGMKIFQLQGELSERL--IQAFQTLFI----PGYWFFPTKNNRRMRA 878 ++I FG F+ FQ +L + + ++A +T + P F ++ + + Sbjct: 190 NIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLFS 249 Query: 879 IDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGLSIEDIIQECK 1058 +++++ + +I K K+ M + G E++I Sbjct: 250 NWKKLKLFVSHMIDKHR---KDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEENLICSTL 306 Query: 1059 LFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGR-TTPDFESLSRLKIVTMIF 1235 +FAG ETTS L W L+ ++++PE QEK + E+ G+ P + + + Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVI 366 Query: 1236 YEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWGKDAREFNPER 1412 +EV R+ I + R L G P G ++ + +H DP W FNP+ Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWA-TPDTFNPDH 425 Query: 1413 FADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALSTILQRFSF 1556 F + + K+ AF PF G R C+G+ A E + ++++Q+F+F Sbjct: 426 FLE--NGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTF 471
>Q2XNC9:CP2D6_PANPA Cytochrome P450 2D6 - Pan paniscus (Pygmy chimpanzee) (Bonobo)| Length = 497 Score = 95.1 bits (235), Expect = 9e-19 Identities = 58/193 (30%), Positives = 96/193 (49%), Gaps = 2/193 (1%) Frame = +3 Query: 990 NMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLH 1169 N + S NL + + D+ + AGM TTS L W L+++ +HP+ Q + ++E+ Sbjct: 285 NPESSFNDENLRIVVADL-------FSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDD 337 Query: 1170 YFGRTT-PDFESLSRLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLML 1343 G+ P+ +R+ T + +EV R + +T T + +E+ G + P G L Sbjct: 338 VIGQVRRPEMGDQARMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLFT 397 Query: 1344 PILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKM 1523 + + D +W K R F+PE F D + K P AF PF G R C+G+ A E + Sbjct: 398 NLSSVLKDEAVWEKPFR-FHPEHFLDAQGHFVK-PEAFLPFSAGRRACLGEPLARMELFL 455 Query: 1524 ALSTILQRFSFEL 1562 +++LQ FSF + Sbjct: 456 FFTSLLQHFSFSV 468
>P00185:CP1A1_RAT Cytochrome P450 1A1 - Rattus norvegicus (Rat)| Length = 524 Score = 95.1 bits (235), Expect = 9e-19 Identities = 97/425 (22%), Positives = 169/425 (39%), Gaps = 20/425 (4%) Frame = +3 Query: 354 TNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLAN-- 527 T +++G V G TP V++ +++ L + F + L+ANG + Sbjct: 68 TKLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVKQGDDFKGRPDLYSFTLIANGQSMTF 127 Query: 528 --HEGEKWAKHRRILNPAFHHEKIKRMLPVFSAC---------CEEMITRWENSMSAQGL 674 G WA RR+ A I + S+C E +I++++ M+ G Sbjct: 128 NPDSGPLWAARRRLAQNALKSFSIASDPTLASSCYLEEHVSKEAEYLISKFQKLMAEVG- 186 Query: 675 CEVDVCPEFQNLTGDVISRTAFGSNF----QEGMKIFQLQGELSERLIQAFQTLFIPGYW 842 D +VI FG + QE + I L E E + FIP Sbjct: 187 -HFDPFKYLVVSVANVICAICFGRRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPILR 245 Query: 843 FFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANL 1022 + P + + ++++ ++ +I + R + + ++ + AN+ Sbjct: 246 YLPNSSLDAFKDLNKKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQD-RRLDENANV 304 Query: 1023 GLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTT-PDFE 1199 LS + +I + AG +T + ++W+L+ L +P Q K +EE+ GR P Sbjct: 305 QLSDDKVITIVFDLFGAGFDTITTAISWSLMYLVTNPRIQRKIQEELDTVIGRDRQPRLS 364 Query: 1200 SLSRLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDI 1376 +L + E R + F + T + L G P G + + ++HD ++ Sbjct: 365 DRPQLPYLEAFILETFRHSSFVPFTIPHSTIRDTSLNGFYIPKGHCVFVNQWQVNHDQEL 424 Query: 1377 WGKDAREFNPERFADGISNAAKRPAA-FFPFGGGPRICIGQNFALQEAKMALSTILQRFS 1553 WG D EF PERF K + FG G R CIG+ E + L+ +LQ+ Sbjct: 425 WG-DPNEFRPERFLTSSGTLDKHLSEKVILFGLGKRKCIGETIGRLEVFLFLAILLQQME 483 Query: 1554 FELSP 1568 F +SP Sbjct: 484 FNVSP 488
>P00184:CP1A1_MOUSE Cytochrome P450 1A1 - Mus musculus (Mouse)| Length = 524 Score = 95.1 bits (235), Expect = 9e-19 Identities = 99/423 (23%), Positives = 171/423 (40%), Gaps = 18/423 (4%) Frame = +3 Query: 354 TNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGRLLANGLAN-- 527 T +++G V G TP V++ +++ L + F + L+ NG + Sbjct: 68 TRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGKSMTF 127 Query: 528 --HEGEKWAKHRRILNPAFHHEKIKRMLPVFSAC-CEEMITRWEN---SMSAQGLCEVDV 689 G WA RR+ A I S+C EE +++ N S + + EV Sbjct: 128 NPDSGPVWAARRRLAQNALKSFSIASDPTSASSCYLEEHVSKEANYLVSKLQKVMAEVGH 187 Query: 690 CPEFQNLT---GDVISRTAFGSNF----QEGMKIFQLQGELSERLIQAFQTLFIPGYWFF 848 ++ L +VI FG + QE + I L E E + FIP + Sbjct: 188 FDPYKYLVVSVANVICAICFGQRYDHDDQELLSIVNLSNEFGEVTGSGYPADFIPVLRYL 247 Query: 849 PTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQQSNGKANLGL 1028 P + + ++ + ++ +I + R + + ++ + AN+ L Sbjct: 248 PNSSLDAFKDLNDKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQD-RKLDENANVQL 306 Query: 1029 SIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFGRTT-PDFESL 1205 S + +I + AG +T + ++W+L+ L +P Q K +EE+ GR P Sbjct: 307 SDDKVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRDRQPRLSDR 366 Query: 1206 SRLKIVTMIFYEVLRLYPPITF-LTRRTYKAMELGGIKYPAGVNLMLPILFIHHDPDIWG 1382 +L + E R + F + T + L G P G + + ++HD ++WG Sbjct: 367 PQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHDRELWG 426 Query: 1383 KDAREFNPERFADGISNAAKRPAAFFP-FGGGPRICIGQNFALQEAKMALSTILQRFSFE 1559 D EF PERF KR + FG G R CIG+ E + L+ +LQ+ F+ Sbjct: 427 -DPNEFRPERFLTPSGTLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQQIEFK 485 Query: 1560 LSP 1568 +SP Sbjct: 486 VSP 488
>O81971:C71D9_SOYBN Cytochrome P450 71D9 - Glycine max (Soybean)| Length = 496 Score = 95.1 bits (235), Expect = 9e-19 Identities = 97/430 (22%), Positives = 169/430 (39%), Gaps = 10/430 (2%) Frame = +3 Query: 303 PMPPGSHHIAPRVLP--MFTNAIKEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFG 476 P+ H++ LP + ++G + G ++V PE +E++ F Sbjct: 43 PIIGNMHNLVGSPLPHHRLRDLSAKYGSLMHLKLGEVSTIVVSSPEYAKEVMKTHDHIFA 102 Query: 477 KQRSTRIGRLLA---NGLA-NHEGEKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITR 644 + ++ G+A G+ W + R+I A KR+ F EE++T Sbjct: 103 SRPYVLAAEIMDYDFKGVAFTPYGDYWRQLRKIF--ALELLSSKRVQS-FQPIREEVLTS 159 Query: 645 WENSMSAQGLCEVDVCPEFQNLTGDVISRTAFGSNFQEGMKIFQLQGELSERLIQAFQTL 824 + M+ +V+V E + + +RTA GS + K+ + E ++ Sbjct: 160 FIKRMATIEGSQVNVTKEVISTVFTITARTALGSKSRHHQKLISVVTEAAKISGGFDLGD 219 Query: 825 FIPGYWFFPTKNNRR--MRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXXXXXXSNMQ 998 P F + + + + ++ I++ II + A + Sbjct: 220 LYPSVKFLQHMSGLKPKLEKLHQQADQIMQNIINEHREAKSSATGDQGEEEVLLDVLL-- 277 Query: 999 QSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAREEVLHYFG 1178 K GLS E I + G +T+S +TW + + +P EK + EV F Sbjct: 278 ----KKEFGLSDESIKAVIWDIFGGGSDTSSATITWAMAEMIKNPRTMEKVQTEVRRVFD 333 Query: 1179 RT-TPDFESLSRLKIVTMIFYEVLRLYPPITFLT-RRTYKAMELGGIKYPAGVNLMLPIL 1352 + P+ LK + + E LRL+PP L R +A E+ G PA +++ Sbjct: 334 KEGRPNGSGTENLKYLKSVVSETLRLHPPAPLLLPRECGQACEINGYHIPAKSRVIVNAW 393 Query: 1353 FIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRICIGQNFALQEAKMALS 1532 I DP +W +A F PERF + F PFG G R+C G F L + L+ Sbjct: 394 AIGRDPRLW-TEAERFYPERFIERSIEYKSNSFEFIPFGAGRRMCPGLTFGLSNVEYVLA 452 Query: 1533 TILQRFSFEL 1562 ++ F ++L Sbjct: 453 MLMYHFDWKL 462
>Q9W223:CP6D2_DROME Probable cytochrome P450 6d2 - Drosophila melanogaster (Fruit fly)| Length = 512 Score = 94.7 bits (234), Expect = 1e-18 Identities = 104/448 (23%), Positives = 181/448 (40%), Gaps = 47/448 (10%) Frame = +3 Query: 366 KEHGKVSFTWFGPTPRVMVPDPELVREILSNKFGHFGKQRSTRIGR---LLANGLANHEG 536 + GK+ + +++ D +L R+I+++ F F R + L+ L N G Sbjct: 62 RHEGKIVGIYMLNKRSILIRDAQLARQIMTSDFASF-HDRGVYVDEDKDPLSANLFNLRG 120 Query: 537 EKWAKHRRILNPAFHHEKIKRMLPVFSACCEEMITRWENSMSAQGLCEVDVCPEFQNLTG 716 W R+ L P+F KIK M ++++ E ++ EV++ Sbjct: 121 ASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSD--EVEIKDVMTTYAV 178 Query: 717 DVISRTAFG----------SNFQE----------------GMKIF------QLQGELS-- 794 D+I FG + F+E M +F +L L Sbjct: 179 DIIGSVIFGLEIDSFRNPKNEFREISSSTSRDESLLLKIHNMSMFICPPIAKLMNRLGYE 238 Query: 795 ERLIQAFQTLFIPGYWFFPTKNNRRMRAIDREIRMILRGIIGKKERAIKNXXXXXXXXXX 974 R++ + + + F N R + IR+ G IG+ + + + Sbjct: 239 SRILTSLRDMMKRTIEFREEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWD---------- 288 Query: 975 XXXXSNMQQSNGKANLGLSIEDIIQECKLFYFAGMETTSVLLTWTLIVLSMHPEWQEKAR 1154 ++ + +SIE I + LFY AG E+T+ +TL LSM+PE ++A+ Sbjct: 289 -------METAQEQLKSMSIEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQ 341 Query: 1155 EEV--------LHYFGRTTPDFESLSRLKIVTMIFYEVLRLYPPITFLTRRTYKAMELGG 1310 EEV L R T +E++ LK + + E +R YP + FL R + + G Sbjct: 342 EEVDAVLMKHNLKPKDRFT--YEAVQDLKFLDICIMETIRKYPGLPFLNRECTEDYPVPG 399 Query: 1311 IKY--PAGVNLMLPILFIHHDPDIWGKDAREFNPERFADGISNAAKRPAAFFPFGGGPRI 1484 + G +++ + + DP ++ + ++P RF +N AA+ PFG GPR Sbjct: 400 TNHIIAKGTPILISLFGMQRDP-VYFPNPNGYDPHRFDS--NNMNYDQAAYMPFGEGPRH 456 Query: 1485 CIGQNFALQEAKMALSTILQRFSFELSP 1568 CI +K+A++ IL F SP Sbjct: 457 CIALRMGKVNSKVAVAKILANFDLVQSP 484 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 312,041,595 Number of extensions: 6875658 Number of successful extensions: 21117 Number of sequences better than 10.0: 770 Number of HSP's gapped: 19894 Number of HSP's successfully gapped: 909 Length of query: 622 Length of database: 100,686,439 Length adjustment: 119 Effective length of query: 503 Effective length of database: 68,045,334 Effective search space: 34226803002 Effective search space used: 34226803002 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
