>IF5_PHAVU (P48724) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 443

 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 18/44 (40%), Positives = 30/44 (68%), Gaps = 1/44 (2%)
 Frame = -2

Query: 367 IIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFV-KALEPFVKWL 239
           ++++LYD DVL E+ I+LW++KG     + S + K  +PF+ WL
Sbjct: 390 VLKTLYDADVLEEEAIVLWYQKGLKGDNKNSKIWKNAQPFIDWL 433

>IF5Z_ARATH (Q9S825) Probable eukaryotic translation initiation factor 5-2|
           (eIF-5 2)
          Length = 437

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 18/44 (40%), Positives = 31/44 (70%), Gaps = 1/44 (2%)
 Frame = -2

Query: 367 IIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFV-KALEPFVKWL 239
           ++++LYDQD++ E+ +L W+ KG     + S V K ++PFV+WL
Sbjct: 383 VLKALYDQDIIEEEVVLDWYEKGLTGADKSSPVWKNVKPFVEWL 426

>IF5_HUMAN (P55010) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 431

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 4/54 (7%)
 Frame = -2

Query: 388 LMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKAL----EPFVKWL 239
           L+   P I++ +YD D+L E+ I+ W  K S +   +   K +    EPF+KWL
Sbjct: 329 LISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWL 382

>IF5_RAT (Q07205) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 429

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 4/54 (7%)
 Frame = -2

Query: 388 LMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKAL----EPFVKWL 239
           L+   P I++ +YD D+L E+ I+ W  K S +   +   K +    EPF+KWL
Sbjct: 327 LISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWL 380

>IF5_MOUSE (P59325) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 429

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 4/54 (7%)
 Frame = -2

Query: 388 LMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKAL----EPFVKWL 239
           L+   P I++ +YD D+L E+ I+ W  K S +   +   K +    EPF+KWL
Sbjct: 327 LISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWL 380

>IF5_MAIZE (P55876) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 451

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 18/49 (36%), Positives = 29/49 (59%)
 Frame = -2

Query: 385 MKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKALEPFVKWL 239
           +K  P ++++LYD D+L E+TI+ W+            VK  +PFV+WL
Sbjct: 391 LKEVPVVLKALYDGDILDEETIVDWYNDAVAAGKDSQVVKNAKPFVEWL 439

>IF5Y_ARATH (Q9C8F1) Probable eukaryotic translation initiation factor 5-1|
           (eIF-5 1)
          Length = 439

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 17/43 (39%), Positives = 27/43 (62%)
 Frame = -2

Query: 367 IIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKALEPFVKWL 239
           +I+ LYD+D+L ED I+ W+ KG         +K + PF++WL
Sbjct: 390 VIKGLYDEDILDEDVIVEWYNKGVKS---SPVLKNVTPFIEWL 429

>IF5_CAEEL (Q22918) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 436

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
 Frame = -2

Query: 388 LMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKAL----EPFVKWL 239
           L+     II+SLYD+DV  ED+++ W  K S++   +SF K +    +P + WL
Sbjct: 316 LLSKSAHIIKSLYDEDVCEEDSLISWGEKPSSKYVSKSFAKKIIENSQPVLNWL 369

>EI2BE_RABIT (P47823) Translation initiation factor eIF-2B epsilon subunit|
           (eIF-2B GDP-GTP exchange factor)
          Length = 721

 Score = 34.3 bits (77), Expect = 0.074
 Identities = 17/46 (36%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
 Frame = -2

Query: 370 EIIRSLYDQDVLAEDTILLWF-RKGSNQKGRQ-SFVKALEPFVKWL 239
           +++   Y  ++LAE+TIL WF ++    KGRQ    + L+ F++WL
Sbjct: 665 KVLMGFYQLEILAEETILSWFGQRDVTDKGRQLRKNQQLQRFIQWL 710

>EI2BE_HUMAN (Q13144) Translation initiation factor eIF-2B epsilon subunit|
           (eIF-2B GDP-GTP exchange factor)
          Length = 721

 Score = 34.3 bits (77), Expect = 0.074
 Identities = 16/46 (34%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
 Frame = -2

Query: 370 EIIRSLYDQDVLAEDTILLWF-RKGSNQKGRQ-SFVKALEPFVKWL 239
           +++ + Y  ++LAE+TIL WF ++ +  KG+Q    + L+ F++WL
Sbjct: 665 KVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWL 710

>EI2BE_CANAL (P87163) Translation initiation factor eIF-2B epsilon subunit|
           (eIF-2B GDP-GTP exchange factor) (Guanine nucleotide
           exchange factor subunit GCD6) (GCD complex subunit GCD6)
           (Fragment)
          Length = 189

 Score = 33.5 bits (75), Expect = 0.13
 Identities = 15/42 (35%), Positives = 23/42 (54%)
 Frame = -2

Query: 364 IRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKALEPFVKWL 239
           ++S YD +V+ E+ IL W+  G N + R    K    F+ WL
Sbjct: 136 VKSFYDMEVVEEENILKWWNDGENDEVRTLAAK----FITWL 173

>IF5_YEAST (P38431) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 405

 Score = 33.5 bits (75), Expect = 0.13
 Identities = 16/54 (29%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
 Frame = -2

Query: 388 LMKLFPEIIRSLYDQDVLAEDTILLWFRKGSN----QKGRQSFVKALEPFVKWL 239
           L+ L P+I+  LY+ D+++E+ I+ +  K S     ++  +   +A +PF+ WL
Sbjct: 339 LIPLLPKILVQLYNNDIISEEEIMRFGTKSSKKFVPKEVSKKVRRAAKPFITWL 392

>EI2BE_RAT (Q64350) Translation initiation factor eIF-2B epsilon subunit|
           (eIF-2B GDP-GTP exchange factor)
          Length = 716

 Score = 33.5 bits (75), Expect = 0.13
 Identities = 17/52 (32%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
 Frame = -2

Query: 388 LMKLFPEIIRSLYDQDVLAEDTILLWF-RKGSNQKGRQ-SFVKALEPFVKWL 239
           L+    +++ + Y  ++LAE+TIL WF ++    KG+Q    + L+ F++WL
Sbjct: 654 LVPSLAKVLMAFYQLEILAEETILSWFSQRDITDKGQQLRKNQQLQRFIQWL 705

>IF4G1_HUMAN (Q04637) Eukaryotic translation initiation factor 4 gamma 1|
            (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220)
          Length = 1600

 Score = 33.1 bits (74), Expect = 0.17
 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 6/51 (11%)
 Frame = -2

Query: 373  PEIIR----SLYDQDVLAEDTILLW--FRKGSNQKGRQSFVKALEPFVKWL 239
            P ++R    +LYD+DV+ ED    W   +  + Q+G+   +K++  F KWL
Sbjct: 1540 PNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWL 1590

>IF4G1_RABIT (P41110) Eukaryotic translation initiation factor 4 gamma 1|
            (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220)
          Length = 1402

 Score = 31.2 bits (69), Expect = 0.63
 Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
 Frame = -2

Query: 358  SLYDQDVLAEDTILLW--FRKGSNQKGRQSFVKALEPFVKWL 239
            +LYD+DV+ E+    W   +  + Q+G+   +K++  F KWL
Sbjct: 1350 ALYDEDVVKEEAFYSWESSKDPAEQQGKGVALKSVTAFFKWL 1391

>IF4G1_MOUSE (Q6NZJ6) Eukaryotic translation initiation factor 4 gamma 1|
            (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1)
          Length = 1600

 Score = 30.8 bits (68), Expect = 0.82
 Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
 Frame = -2

Query: 358  SLYDQDVLAEDTILLW--FRKGSNQKGRQSFVKALEPFVKWL 239
            +LYD+DV+ ED    W   +  + Q+G+   +K++  F  WL
Sbjct: 1548 ALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFNWL 1589

>EI2BE_YEAST (P32501) Translation initiation factor eIF-2B epsilon subunit|
           (eIF-2B GDP-GTP exchange factor) (Guanine nucleotide
           exchange factor subunit GCD6) (GCD complex subunit GCD6)
          Length = 712

 Score = 30.8 bits (68), Expect = 0.82
 Identities = 16/47 (34%), Positives = 23/47 (48%)
 Frame = -2

Query: 379 LFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKALEPFVKWL 239
           LF  ++ SLYD D++ ED I  W+   S         K    +V+WL
Sbjct: 655 LFSALV-SLYDNDIIEEDVIYKWWDNVSTDPRYDEVKKLTVKWVEWL 700

>IF5_DROME (Q9VXK6) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 464

 Score = 30.0 bits (66), Expect = 1.4
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 4/54 (7%)
 Frame = -2

Query: 388 LMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKALE----PFVKWL 239
           LM     I +  YD D+L E  IL W +K S +   ++    +     PFV WL
Sbjct: 352 LMSKVAGIFKLFYDLDILDEAVILEWAQKVSKRHVSKNIAAEIHEKAMPFVLWL 405

>SRG53_CAEEL (O16974) Serpentine receptor class gamma-53 (Protein srg-53)|
          Length = 295

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 12/64 (18%)
 Frame = -1

Query: 179 LYPMFVEAVDITFYFSHV-------SIAVICCR-----LRHYCTRIWKERYLLCRVLVVT 36
           LY  + ++ D++F+ S+V       S   ICC      +     R W   YLL   L++ 
Sbjct: 72  LYEFYNKSFDVSFFLSNVFFHVQSASTICICCHRLSTAIFDNSNRFWSRFYLLVYALIIL 131

Query: 35  WIFM 24
           + F+
Sbjct: 132 YSFL 135

>SIL1_DEBHA (Q6BTV5) Nucleotide exchange factor SIL1 precursor|
          Length = 427

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 15/49 (30%), Positives = 22/49 (44%)
 Frame = -2

Query: 355 LYDQDVLAEDTILLWFRKGSNQKGRQSFVKALEPFVKWLXXXXXXX*KG 209
           L D  V +ED   L+F K S    +   +K  + F++WL        KG
Sbjct: 338 LADSGVASEDQFKLYFNKLSEVHSQDKSLKPSKAFMEWLSKEAELRSKG 386

>IF4G3_HUMAN (O43432) Eukaryotic translation initiation factor 4 gamma 3|
            (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II)
            (eIF4GII)
          Length = 1585

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
 Frame = -2

Query: 355  LYDQDVLAEDTILLW--FRKGSNQKGRQSFVKALEPFVKWL 239
            LYD++V++ED    W   +  + Q G+   +K++  F  WL
Sbjct: 1535 LYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWL 1575

>HV1D_HUMAN (P01760) Ig heavy chain V-I region WOL|
          Length = 124

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = -1

Query: 218 IKRPGSCFKMSISLYPMFVEA-VDITFYFSHVSIAVICCR 102
           +K PGS  ++S+SL P F +A ++++  FS  +    C R
Sbjct: 59  VKNPGSVVRVSVSLKPSFNQAHMELSSLFSEDTAVYYCAR 98

>IF4G3_MOUSE (Q80XI3) Eukaryotic translation initiation factor 4 gamma 3|
            (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II)
            (eIF4GII)
          Length = 1579

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
 Frame = -2

Query: 355  LYDQDVLAEDTILLW--FRKGSNQKGRQSFVKALEPFVKWL 239
            LYD++V++ED    W   +  + Q G+   +K++  F  WL
Sbjct: 1529 LYDEEVISEDAFYKWESSKDPAEQAGKGVALKSVTAFFTWL 1569

>TTC8_HUMAN (Q8TAM2) Tetratricopeptide repeat protein 8 (TPR repeat protein 8)|
           (Bardet-Biedl syndrome 8 protein)
          Length = 531

 Score = 27.3 bits (59), Expect = 9.1
 Identities = 12/40 (30%), Positives = 21/40 (52%)
 Frame = -1

Query: 197 FKMSISLYPMFVEAVDITFYFSHVSIAVICCRLRHYCTRI 78
           F+ ++SL     EA D+ +   HV++ +    L H C R+
Sbjct: 399 FERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRL 438

>JHD3B_MOUSE (Q91VY5) JmjC domain-containing histone demethylation protein 3B|
           (EC 1.14.11.-) (Jumonji domain-containing protein 2B)
          Length = 1086

 Score = 27.3 bits (59), Expect = 9.1
 Identities = 9/24 (37%), Positives = 14/24 (58%)
 Frame = -3

Query: 87  YPDLEGTLPTLSCTSCYMDIYAKC 16
           Y   +GT P +SC  C + ++A C
Sbjct: 736 YVGEDGTSPLISCAHCCLQVHASC 759

>Y1060_SYNY3 (P72637) UPF0182 protein sll1060|
          Length = 1032

 Score = 27.3 bits (59), Expect = 9.1
 Identities = 12/26 (46%), Positives = 17/26 (65%)
 Frame = -2

Query: 373 PEIIRSLYDQDVLAEDTILLWFRKGS 296
           PE I +L +QD +  + I LW R+GS
Sbjct: 922 PEQIEALVNQDPVISERISLWNRRGS 947


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,880,770
Number of Sequences: 219361
Number of extensions: 1033041
Number of successful extensions: 2253
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 2225
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2253
length of database: 80,573,946
effective HSP length: 105
effective length of database: 57,541,041
effective search space used: 1380984984
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)