>CATB_MOUSE (P10605) Cathepsin B precursor (EC 3.4.22.1) (Cathepsin B1)|
           [Contains: Cathepsin B light chain; Cathepsin B heavy
           chain]
          Length = 339

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 34/86 (39%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +3

Query: 216 IQEDIIQTVNDHPNAGWTAGHNPYFANYTIEQFKHILGVK---PTPPGLLAGVPIKTHPK 386
           + +D+I  +N   N  W AG N  F N  I   K + G     P  PG +A        +
Sbjct: 26  LSDDLINYINKQ-NTTWQAGRN--FYNVDISYLKKLCGTVLGGPKLPGRVA------FGE 76

Query: 387 SADLPKGFDARTQWSSCSTIGNILDQ 464
             DLP+ FDAR QWS+C TIG I DQ
Sbjct: 77  DIDLPETFDAREQWSNCPTIGQIRDQ 102

>CYSP_SCHMA (P25792) Cathepsin B-like cysteine proteinase precursor (EC|
           3.4.22.-) (Antigen Sm31)
          Length = 340

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
 Frame = +3

Query: 216 IQEDIIQTVNDHPNAGWTAGHNPYFANYTIEQFKHILGVKPTPPGL--LAGVPIKTHPKS 389
           + +DII  +N+HPNAGW A  +  F  ++++  +  +G +   P L       +  +  +
Sbjct: 29  LSDDIISYINEHPNAGWRAEKSNRF--HSLDDARIQMGARREEPDLRRKRRPTVDHNDWN 86

Query: 390 ADLPKGFDARTQWSSCSTIGNILDQ 464
            ++P  FD+R +W  C +I  I DQ
Sbjct: 87  VEIPSNFDSRKKWPGCKSIATIRDQ 111

>CATB_RAT (P00787) Cathepsin B precursor (EC 3.4.22.1) (Cathepsin B1) (RSG-2)|
           [Contains: Cathepsin B light chain; Cathepsin B heavy
           chain]
          Length = 339

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 31/83 (37%), Positives = 40/83 (48%)
 Frame = +3

Query: 216 IQEDIIQTVNDHPNAGWTAGHNPYFANYTIEQFKHILGVKPTPPGLLAGVPIKTHPKSAD 395
           + +D+I  +N   N  W AG N  F N  I   K + G     P L   V      +  +
Sbjct: 26  LSDDMINYINKQ-NTTWQAGRN--FYNVDISYLKKLCGTVLGGPNLPERVGFS---EDIN 79

Query: 396 LPKGFDARTQWSSCSTIGNILDQ 464
           LP+ FDAR QWS+C TI  I DQ
Sbjct: 80  LPESFDAREQWSNCPTIAQIRDQ 102

>CYSP_SCHJA (P43157) Cathepsin B-like cysteine proteinase precursor (EC|
           3.4.22.-) (Antigen Sj31)
          Length = 342

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 21/85 (24%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
 Frame = +3

Query: 216 IQEDIIQTVNDHPNAGWTAGHNPYFANYTIEQFKHILGVKPTPPGLLAG--VPIKTHPKS 389
           + +++I  +N+HP+AGW A  +  F  ++++  + ++G +     +       +  H  +
Sbjct: 30  LSDEMISFINEHPDAGWKADKSDRF--HSLDDARILMGARKEDAEMKRNRRPTVDHHDLN 87

Query: 390 ADLPKGFDARTQWSSCSTIGNILDQ 464
            ++P  FD+R +W  C +I  I DQ
Sbjct: 88  VEIPSQFDSRKKWPHCKSISQIRDQ 112

>CATB_HUMAN (P07858) Cathepsin B precursor (EC 3.4.22.1) (Cathepsin B1) (APP|
           secretase) (APPS) [Contains: Cathepsin B light chain;
           Cathepsin B heavy chain]
          Length = 339

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
 Frame = +3

Query: 216 IQEDIIQTVNDHPNAGWTAGHNPYFANYTIEQFKHILGV---KPTPPGLLAGVPIKTHPK 386
           + ++++  VN   N  W AGHN  F N  +   K + G     P PP  +         +
Sbjct: 26  LSDELVNYVNKR-NTTWQAGHN--FYNVDMSYLKRLCGTFLGGPKPPQRVM------FTE 76

Query: 387 SADLPKGFDARTQWSSCSTIGNILDQ 464
              LP  FDAR QW  C TI  I DQ
Sbjct: 77  DLKLPASFDAREQWPQCPTIKEIRDQ 102

>CATB_BOVIN (P07688) Cathepsin B precursor (EC 3.4.22.1) [Contains: Cathepsin B|
           light chain; Cathepsin B heavy chain]
          Length = 335

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
 Frame = +3

Query: 216 IQEDIIQTVNDHPNAGWTAGHNPYFANYTIEQFKHILGVKPTPPGLLAGVPIKTHPKSAD 395
           + ++++  VN   N  W AGHN  F N  +   K + G       +L G  +      A 
Sbjct: 26  LSDELVNFVNKQ-NTTWKAGHN--FYNVDLSYVKKLCGA------ILGGPKLPQRDAFAA 76

Query: 396 ---LPKGFDARTQWSSCSTIGNILDQ 464
              LP+ FDAR QW +C TI  I DQ
Sbjct: 77  DVVLPESFDAREQWPNCPTIKEIRDQ 102

>CATB_CHICK (P43233) Cathepsin B precursor (EC 3.4.22.1) (Cathepsin B1)|
           [Contains: Cathepsin B light chain; Cathepsin B heavy
           chain]
          Length = 340

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 27/83 (32%), Positives = 35/83 (42%)
 Frame = +3

Query: 216 IQEDIIQTVNDHPNAGWTAGHNPYFANYTIEQFKHILGVKPTPPGLLAGVPIKTHPKSAD 395
           +  D++  +N     G  AGHN  F N  +   K + G     P     V      +  D
Sbjct: 26  LSSDLVNHINKLNTTG-RAGHN--FHNTDMSYVKKLCGTFLGGPKAPERVDFA---EDMD 79

Query: 396 LPKGFDARTQWSSCSTIGNILDQ 464
           LP  FD R QW +C TI  I DQ
Sbjct: 80  LPDTFDTRKQWPNCPTISEIRDQ 102

>CPR4_CAEEL (P43508) Cathepsin B-like cysteine proteinase 4 precursor (EC|
           3.4.22.-) (Cysteine protease-related 4)
          Length = 335

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 26/60 (43%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
 Frame = +3

Query: 300 TIEQFKHILG----VKPTPPGLLAGVPIKTHPKSAD-LPKGFDARTQWSSCSTIGNILDQ 464
           TIEQ K  L     V P  P     V +  H  + D +P  FDARTQW +C +I NI DQ
Sbjct: 48  TIEQVKKRLMRTEFVAPHTPD----VEVVKHDINEDTIPATFDARTQWPNCMSINNIRDQ 103

>CPR6_CAEEL (P43510) Cathepsin B-like cysteine proteinase 6 precursor (EC|
           3.4.22.-) (Cysteine protease-related 6)
          Length = 379

 Score = 36.2 bits (82), Expect = 0.043
 Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
 Frame = +3

Query: 222 EDIIQTVNDHPNAGWTAGHNPYFANYTIEQFKH---ILGVKPTPPGLLAGVPI-KTHPKS 389
           +D+I  VN++ N  WTA     F++   E  K    ++GV      +     + KT    
Sbjct: 44  DDLIDYVNENQNL-WTAKKQRRFSSVYGENDKAKWGLMGVNHVRLSVKGKQHLSKTKDLD 102

Query: 390 ADLPKGFDARTQWSSCSTIGNILDQ 464
            D+P+ FD+R  W  C +I  I DQ
Sbjct: 103 LDIPESFDSRDNWPKCDSIKVIRDQ 127

>CPR5_CAEEL (P43509) Cathepsin B-like cysteine proteinase 5 precursor (EC|
           3.4.22.-) (Cysteine protease-related 5)
          Length = 344

 Score = 35.4 bits (80), Expect = 0.073
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
 Frame = +3

Query: 234 QTVNDHPNAG---WTAGHNPYFANYTIEQFKHILGVKPTPPGLLAGVPIKTHPKSADLPK 404
           Q + D+ N+    WTAGH         ++   +  + P     +    +     S  +P 
Sbjct: 30  QALIDYVNSAQKLWTAGHQVIPKEKITKKLMDVKYLVPHKDEDIVATEV-----SDAIPD 84

Query: 405 GFDARTQWSSCSTIGNILDQ 464
            FDAR QW +C +I NI DQ
Sbjct: 85  HFDARDQWPNCMSINNIRDQ 104

>CPR1_CAEEL (P25807) Gut-specific cysteine proteinase precursor (EC 3.4.22.-)|
          Length = 329

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 14/25 (56%), Positives = 17/25 (68%)
 Frame = +3

Query: 390 ADLPKGFDARTQWSSCSTIGNILDQ 464
           A +P  FD+RTQWS C +I  I DQ
Sbjct: 83  ASVPATFDSRTQWSECKSIKLIRDQ 107

>CYSP1_OSTOS (P25802) Cathepsin B-like cysteine proteinase 1 precursor (EC|
           3.4.22.-)
          Length = 341

 Score = 32.3 bits (72), Expect = 0.62
 Identities = 11/24 (45%), Positives = 19/24 (79%)
 Frame = +3

Query: 393 DLPKGFDARTQWSSCSTIGNILDQ 464
           D+P+ +D R QW++CS++ +I DQ
Sbjct: 90  DIPESYDPRIQWANCSSLFHIPDQ 113

>CATB_COTJA (P81494) Cathepsin B (EC 3.4.22.1) (Cathepsin B1) (Fragments)|
          Length = 48

 Score = 32.0 bits (71), Expect = 0.80
 Identities = 13/23 (56%), Positives = 15/23 (65%)
 Frame = +3

Query: 396 LPKGFDARTQWSSCSTIGNILDQ 464
           LP  FD+R QW +C TI  I DQ
Sbjct: 1   LPDTFDSRKQWPNCPTISEIRDQ 23

>PI5PA_RAT (Q9JMC1) Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC|
            3.1.3.56) (Proline-rich inositol polyphosphate
            5-phosphatase)
          Length = 1001

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 24/82 (29%), Positives = 31/82 (37%), Gaps = 8/82 (9%)
 Frame = +2

Query: 185  SSQGRAFPRNHPGRHHSDGQRPSQCRVDG-----WTQPLLCKLHY*AIQAYPGSEANASG 349
            S Q R  PR  P R HS G R S           W  P         + A      +  G
Sbjct: 909  SPQSRQLPRVAPDRGHSSGSRGSSEEGPSGPPGPWAFPPAVPRSLGLLPALRLETVDPGG 968

Query: 350  LARWRPNQ---NPSKISRSPEG 406
               W P+Q   +P+ +S SP+G
Sbjct: 969  GGSWGPDQEAPDPNSLSPSPQG 990

>GMH3_SCHPO (Q10359) Alpha-1,2-galactosyltransferase gmh3 (EC 2.4.1.-)|
          Length = 332

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
 Frame = +3

Query: 228 IIQTVNDHPNAGWT--AGHNPYFANYTIEQFKHILGVKPTPPGLLAGVPIKTHPKSADLP 401
           IIQT+N HP+A W      +    N  +   +HIL        L+   P+   P SADL 
Sbjct: 146 IIQTMNKHPHAKWIWWLDQDALILNTELSIQEHILSPDVLVEKLMKNEPM-ISPFSADLE 204

Query: 402 KGFDARTQWSSCSTIGNILDQ 464
           +   +     S  ++G ++ Q
Sbjct: 205 RLTPSSYTVDSARSLGLLISQ 225

>NKX25_MOUSE (P42582) Homeobox protein Nkx-2.5 (Homeobox protein NK-2 homolog E)|
           (Cardiac-specific homeobox) (Homeobox protein CSX)
          Length = 318

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 16/41 (39%), Positives = 20/41 (48%)
 Frame = +2

Query: 260 RVDGWTQPLLCKLHY*AIQAYPGSEANASGLARWRPNQNPS 382
           R++    P  C L     +AY G EA ASGLA  R    P+
Sbjct: 35  RLEATLAPASCMLAAFKPEAYSGPEAAASGLAELRAEMGPA 75

>PCX1_FUGRU (Q98UF7) Pecanex-like protein 1 (Pecanex homolog)|
          Length = 1703

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = +3

Query: 315 KHILGVKPTPPGLLAGVPIKTHPKSADLPKG 407
           +H  G  PTPP  L G P++     AD P G
Sbjct: 194 RHNAGSNPTPPTSLIGSPLRYALHEADRPSG 224

>SYM_BLOFL (Q7VRX4) Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA|
           ligase) (MetRS)
          Length = 545

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%)
 Frame = -2

Query: 332 HSQDMLELLNSVVCKV---GVVSSRPPGIGMVVDRLNDVFLDD 213
           HS++  ELLNS+  K+   G + SR   I  + D  N++FL D
Sbjct: 97  HSEENYELLNSIYTKLKKSGFIKSR--FISQLYDAQNNIFLPD 137


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,640,532
Number of Sequences: 219361
Number of extensions: 971083
Number of successful extensions: 2992
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 2938
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2990
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3014947676
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)