ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bast73h02 |
|---|---|
| Clone Library Name | barley_pub |
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 213 bits (541), Expect = 2e-55 Identities = 102/114 (89%), Positives = 109/114 (95%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 286 M+KYEPVREIG+GNFGVAKLMRN++TRELVAMKFIERG RIDENVFREIVNHRSLRHPNI Sbjct: 1 MEKYEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGNRIDENVFREIVNHRSLRHPNI 60 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 IRFKEVV+T HL IVMEYAAGGELFERIC+A RFHEDEARYFFQQLVCGVS+C Sbjct: 61 IRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYC 114
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 203 bits (517), Expect = 1e-52 Identities = 95/114 (83%), Positives = 108/114 (94%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 286 M+KYE VR+IGSGNFGVA+LMRNR+TRELVA+K IERG+RIDENV+REI+NHRSLRHPNI Sbjct: 1 MEKYEAVRDIGSGNFGVARLMRNRETRELVAVKCIERGHRIDENVYREIINHRSLRHPNI 60 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 IRFKEV+LTPTHL IVME+AAGGELF+RICD RF EDEARYFFQQL+CGVS+C Sbjct: 61 IRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYC 114
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 197 bits (502), Expect = 8e-51 Identities = 92/114 (80%), Positives = 106/114 (92%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 286 M+KYE +++IGSGNFGVA+LMRNR+T+ELVAMK+I RG +IDENV REI+NHRSLRHPNI Sbjct: 1 MEKYELLKDIGSGNFGVARLMRNRETKELVAMKYIPRGLKIDENVAREIINHRSLRHPNI 60 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 IRFKEVVLTPTHL IVMEYAAGGELF+RIC A RF EDE+RYFFQQL+CGVS+C Sbjct: 61 IRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYC 114
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 194 bits (494), Expect = 7e-50 Identities = 89/114 (78%), Positives = 107/114 (93%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 286 M++YE +++IG+GNFGVA+LMRN++T+ELVAMK+I RG +IDENV REI+NHRSLRHPNI Sbjct: 1 MERYELLKDIGAGNFGVARLMRNKETKELVAMKYIPRGLKIDENVAREIINHRSLRHPNI 60 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 IRFKEVV+TPTHL IVMEYAAGGELF+RIC+A RF EDEARYFFQQL+CGVS+C Sbjct: 61 IRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYC 114
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 190 bits (483), Expect = 1e-48 Identities = 86/114 (75%), Positives = 105/114 (92%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 286 MDKY+ V+++G+GNFGVA+L+R++DT+ELVAMK+IERG +IDENV REI+NHRSL+HPNI Sbjct: 1 MDKYDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRKIDENVAREIINHRSLKHPNI 60 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 IRFKEV+LTPTHL IVMEYA+GGELF+RIC A RF E EARYFFQQL+CGV +C Sbjct: 61 IRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYC 114
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 190 bits (482), Expect = 2e-48 Identities = 90/114 (78%), Positives = 104/114 (91%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 286 MDKYE V++IG+GNFGVA+LM+ ++++ELVAMK+IERG +IDENV REI+NHRSLRHPNI Sbjct: 1 MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPKIDENVAREIINHRSLRHPNI 60 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 IRFKEVVLTPTHL I MEYAAGGELFERIC A RF EDEARYFFQQL+ GVS+C Sbjct: 61 IRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYC 114
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 187 bits (474), Expect = 1e-47 Identities = 88/113 (77%), Positives = 103/113 (91%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNII 289 D+YE V+EIGSGNFGVA+LMRNR + +LVA+K+I+RG +IDENV REI+NHRSLRHPNII Sbjct: 20 DRYELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGEKIDENVQREIINHRSLRHPNII 79 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 RFKEV+LTPTHL IVMEYA+GGELFERIC A RF EDEAR+FFQQL+ GVS+C Sbjct: 80 RFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYC 132
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 186 bits (472), Expect = 2e-47 Identities = 88/114 (77%), Positives = 103/114 (90%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 286 M++YE +++IGSGNFGVAKL+R+ T+EL A+KFIERG +IDENV REI+NHRSLRHPNI Sbjct: 1 MERYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQKIDENVQREIMNHRSLRHPNI 60 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 +RFKEVVLTPTHL IVMEYAAGGELFERIC A RF EDEAR+FFQQL+ GVS+C Sbjct: 61 VRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYC 114
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 186 bits (471), Expect = 3e-47 Identities = 88/113 (77%), Positives = 102/113 (90%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNII 289 D+YE VR+IGSGNFGVA+LMR+R T ELVA+K+IERG +ID+NV REI+NHRSL+HPNII Sbjct: 31 DRYELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGEKIDDNVQREIINHRSLKHPNII 90 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 RFKEV+LTPTHL IVMEYA+GGELFERIC RF EDEARYFFQQL+ GVS+C Sbjct: 91 RFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYC 143
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 185 bits (470), Expect = 4e-47 Identities = 88/113 (77%), Positives = 103/113 (91%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNII 289 D+YE VR+IGSGNFGVA+LMR+R +LVA+K+IERG +IDENV REI+NHRSLRHPNII Sbjct: 21 DRYELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGDKIDENVQREIINHRSLRHPNII 80 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 RFKEV+LTPTHL IVMEYA+GGELFERIC+A RF EDEAR+FFQQL+ GVS+C Sbjct: 81 RFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYC 133
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 181 bits (460), Expect = 6e-46 Identities = 87/114 (76%), Positives = 102/114 (89%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 286 M++YE +R+IGSGNFGVAKL+R+ T L A+KFIERG +IDE+V REI+NHRSL+HPNI Sbjct: 1 MERYEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIERGLKIDEHVQREIMNHRSLKHPNI 60 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 IRFKEVVLTPTHL IVMEYAAGGELFERIC+A RF EDEAR+FFQQL+ GVS+C Sbjct: 61 IRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYC 114
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 181 bits (460), Expect = 6e-46 Identities = 84/113 (74%), Positives = 103/113 (91%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNII 289 ++YE ++E+G+GNFGVA+L+R++ ++ELVA+K+IERG +IDENV REI+NHRSLRHPNII Sbjct: 3 ERYEALKELGAGNFGVARLVRDKRSKELVAVKYIERGKKIDENVQREIINHRSLRHPNII 62 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 RFKEV LTPTHL IVMEYAAGGELFE+IC A RF EDEARYFFQQL+ GVS+C Sbjct: 63 RFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYC 115
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 167 bits (422), Expect = 1e-41 Identities = 79/104 (75%), Positives = 94/104 (90%) Frame = +2 Query: 137 GSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNIIRFKEVVLTP 316 GSGNFGVAKL+R+ T+E A+KFIERG++IDE+V REI+NHRSL+HPNIIRFKEVVLTP Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIERGHKIDEHVQREIMNHRSLKHPNIIRFKEVVLTP 60 Query: 317 THLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 THL IVMEYA+GGELF+RIC+A RF EDE R+FFQQL+ GVS+C Sbjct: 61 THLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYC 104
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 93.6 bits (231), Expect = 2e-19 Identities = 53/126 (42%), Positives = 72/126 (57%), Gaps = 4/126 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFRE 250 SR S + Y+ R +G G+FG K+ + T VA+K + R ++E V RE Sbjct: 31 SRSGVESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRRE 90 Query: 251 IVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 I R HP+IIR EV+ TPT + +VMEY GELF+ I + R EDEAR FFQQ++ Sbjct: 91 IKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQII 150 Query: 431 CGVSFC 448 GV +C Sbjct: 151 SGVEYC 156
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 93.2 bits (230), Expect = 3e-19 Identities = 50/116 (43%), Positives = 70/116 (60%), Gaps = 4/116 (3%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENVFREIVNHRSLRHP 280 KYE R IG G F K RN DT + VA+K + + R+ + + REI + +RHP Sbjct: 10 KYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHP 69 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 NI+R EV+ +P+ + IV+E+ GGELF+RI R E E+R +FQQLV V+ C Sbjct: 70 NIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHC 125
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 90.1 bits (222), Expect = 2e-18 Identities = 50/113 (44%), Positives = 72/113 (63%), Gaps = 5/113 (4%) Frame = +2 Query: 125 VRE-IGSGNFGVAKLMRNRDTRELVAMKFIERGYR----IDENVFREIVNHRSLRHPNII 289 +RE +G G+FG KL + T++ VA+KFI R + V REI + LRHP+II Sbjct: 36 IRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPHII 95 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 + +V+ TPT + +V+EYA GGELF+ I + R EDE R FFQQ++C + +C Sbjct: 96 KLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYC 147
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 89.4 bits (220), Expect = 4e-18 Identities = 46/116 (39%), Positives = 69/116 (59%), Gaps = 4/116 (3%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG----YRIDENVFREIVNHRSLRHP 280 KYE R IG G F + +N + E VA+K +++ +R+ E + REI + ++HP Sbjct: 19 KYELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHP 78 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 N++R EV+ + + IV+EY GGELFE I R E+EAR +FQQL+ V +C Sbjct: 79 NVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYC 134
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 86.7 bits (213), Expect = 2e-17 Identities = 46/132 (34%), Positives = 72/132 (54%), Gaps = 4/132 (3%) Frame = +2 Query: 65 RKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN-- 238 R+ + + + KYE R +G GNFG K ++ + A+K I++ D N Sbjct: 3 RRQEEEKKAEKGMRLGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFS 62 Query: 239 --VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARY 412 + REI + L+HP+I+R EV+ + T + +VME GGELF+RI + E + R Sbjct: 63 LQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRK 122 Query: 413 FFQQLVCGVSFC 448 FQQL+ G+S+C Sbjct: 123 MFQQLIDGISYC 134
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 85.5 bits (210), Expect = 6e-17 Identities = 47/118 (39%), Positives = 68/118 (57%), Gaps = 4/118 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLR 274 + Y+ + +G G+FG K+ + T VA+K + R ++E V REI R Sbjct: 17 LPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 76 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 HP+IIR EV+ T + + +VMEY GELF+ I + R EDEAR FFQQ++ GV +C Sbjct: 77 HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYC 134
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 84.0 bits (206), Expect = 2e-16 Identities = 50/139 (35%), Positives = 75/139 (53%), Gaps = 3/139 (2%) Frame = +2 Query: 41 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 220 +SR + + S S E+ + Y +R IG GNF KL R+ T VA+K I++ Sbjct: 34 SSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKT 93 Query: 221 YRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRF 391 + +FRE+ + L HPNI++ EV+ T L +VMEYA+ GE+F+ + R Sbjct: 94 QLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRM 153 Query: 392 HEDEARYFFQQLVCGVSFC 448 E EAR F+Q+V V +C Sbjct: 154 KEKEARAKFRQIVSAVHYC 172
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 84.0 bits (206), Expect = 2e-16 Identities = 50/139 (35%), Positives = 75/139 (53%), Gaps = 3/139 (2%) Frame = +2 Query: 41 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 220 +SR + + S S E+ + Y +R IG GNF KL R+ T VA+K I++ Sbjct: 34 SSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKT 93 Query: 221 YRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRF 391 + +FRE+ + L HPNI++ EV+ T L +VMEYA+ GE+F+ + R Sbjct: 94 QLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRM 153 Query: 392 HEDEARYFFQQLVCGVSFC 448 E EAR F+Q+V V +C Sbjct: 154 KEKEARAKFRQIVSAVHYC 172
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 83.6 bits (205), Expect = 2e-16 Identities = 46/130 (35%), Positives = 72/130 (55%), Gaps = 4/130 (3%) Frame = +2 Query: 71 TSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDEN 238 T+ + + R + Y +G G FG K+ ++ T VA+K + R + Sbjct: 3 TAEKQKHDGRVRIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGK 62 Query: 239 VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFF 418 + REI N + RHP+II+ +V+ TP+ + +VMEY +GGELF+ IC R E E+R F Sbjct: 63 IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 122 Query: 419 QQLVCGVSFC 448 QQ++ GV +C Sbjct: 123 QQILSGVDYC 132
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 83.6 bits (205), Expect = 2e-16 Identities = 46/130 (35%), Positives = 72/130 (55%), Gaps = 4/130 (3%) Frame = +2 Query: 71 TSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDEN 238 T+ + + R + Y +G G FG K+ ++ T VA+K + R + Sbjct: 3 TAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGK 62 Query: 239 VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFF 418 + REI N + RHP+II+ +V+ TP+ + +VMEY +GGELF+ IC R E E+R F Sbjct: 63 IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 122 Query: 419 QQLVCGVSFC 448 QQ++ GV +C Sbjct: 123 QQILSGVDYC 132
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 83.2 bits (204), Expect = 3e-16 Identities = 43/109 (39%), Positives = 65/109 (59%), Gaps = 4/109 (3%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 301 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 81 Query: 302 VVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 V+ TP+ + +VMEY +GGELF+ IC R E E+R FQQ++ GV +C Sbjct: 82 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYC 130
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 83.2 bits (204), Expect = 3e-16 Identities = 43/109 (39%), Positives = 65/109 (59%), Gaps = 4/109 (3%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 301 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 81 Query: 302 VVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 V+ TP+ + +VMEY +GGELF+ IC R E E+R FQQ++ GV +C Sbjct: 82 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYC 130
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 82.8 bits (203), Expect = 4e-16 Identities = 51/142 (35%), Positives = 79/142 (55%), Gaps = 3/142 (2%) Frame = +2 Query: 32 SAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 211 S P+S+ + S S + E+ + Y ++ IG GNF KL R+ T + VA+K I Sbjct: 26 SKPSSKSNMIRGRNSATSAD-EQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKII 84 Query: 212 ERGYRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA 382 ++ + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + Sbjct: 85 DKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAH 144 Query: 383 XRFHEDEARYFFQQLVCGVSFC 448 R E EAR F+Q+V V +C Sbjct: 145 GRMKEKEARAKFRQIVSAVQYC 166
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 82.8 bits (203), Expect = 4e-16 Identities = 51/142 (35%), Positives = 79/142 (55%), Gaps = 3/142 (2%) Frame = +2 Query: 32 SAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 211 S P+S+ + S S + E+ + Y ++ IG GNF KL R+ T + VA+K I Sbjct: 26 SKPSSKSNMLRGRNSATSAD-EQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKII 84 Query: 212 ERGYRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA 382 ++ + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + Sbjct: 85 DKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAH 144 Query: 383 XRFHEDEARYFFQQLVCGVSFC 448 R E EAR F+Q+V V +C Sbjct: 145 GRMKEKEARAKFRQIVSAVQYC 166
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 82.0 bits (201), Expect = 6e-16 Identities = 51/142 (35%), Positives = 79/142 (55%), Gaps = 3/142 (2%) Frame = +2 Query: 32 SAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 211 S P+S+ + S S + E+ + Y ++ IG GNF KL R+ T + VA+K I Sbjct: 26 SKPSSKSNMLRGRNSATSAD-EQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKII 84 Query: 212 ERGYRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA 382 ++ + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + Sbjct: 85 DKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAH 144 Query: 383 XRFHEDEARYFFQQLVCGVSFC 448 R E EAR F+Q+V V +C Sbjct: 145 GRMKEKEARAKFRQIVLHVQYC 166
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 82.0 bits (201), Expect = 6e-16 Identities = 44/109 (40%), Positives = 63/109 (57%), Gaps = 4/109 (3%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 301 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 302 VVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 V+ TPT +VMEY +GGELF+ IC R E EAR FQQ++ V +C Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYC 130
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 82.0 bits (201), Expect = 6e-16 Identities = 44/109 (40%), Positives = 63/109 (57%), Gaps = 4/109 (3%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 301 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 302 VVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 V+ TPT +VMEY +GGELF+ IC R E EAR FQQ++ V +C Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 82.0 bits (201), Expect = 6e-16 Identities = 44/109 (40%), Positives = 63/109 (57%), Gaps = 4/109 (3%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 301 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 302 VVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 V+ TPT +VMEY +GGELF+ IC R E EAR FQQ++ V +C Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 82.0 bits (201), Expect = 6e-16 Identities = 44/109 (40%), Positives = 63/109 (57%), Gaps = 4/109 (3%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 301 +G G FG K+ ++ T VA+K + R + + REI N + RHP+II+ + Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 302 VVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 V+ TPT +VMEY +GGELF+ IC R E EAR FQQ++ V +C Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYC 130
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 80.9 bits (198), Expect = 1e-15 Identities = 50/139 (35%), Positives = 75/139 (53%), Gaps = 3/139 (2%) Frame = +2 Query: 41 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 220 +SR+ + S S E+ + Y + IG GNF KL R+ T VA+K I++ Sbjct: 35 SSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKT 94 Query: 221 YRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRF 391 + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + R Sbjct: 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRM 154 Query: 392 HEDEARYFFQQLVCGVSFC 448 E EAR F+Q+V V +C Sbjct: 155 KEKEARAKFRQIVSAVQYC 173
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 80.9 bits (198), Expect = 1e-15 Identities = 50/139 (35%), Positives = 75/139 (53%), Gaps = 3/139 (2%) Frame = +2 Query: 41 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 220 +SR+ + S S E+ + Y + IG GNF KL R+ T VA+K I++ Sbjct: 35 SSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKT 94 Query: 221 YRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRF 391 + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + R Sbjct: 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRM 154 Query: 392 HEDEARYFFQQLVCGVSFC 448 E EAR F+Q+V V +C Sbjct: 155 KEKEARAKFRQIVSAVQYC 173
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 80.9 bits (198), Expect = 1e-15 Identities = 50/139 (35%), Positives = 75/139 (53%), Gaps = 3/139 (2%) Frame = +2 Query: 41 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 220 +SR+ + S S E+ + Y + IG GNF KL R+ T VA+K I++ Sbjct: 35 SSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKT 94 Query: 221 YRID---ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRF 391 + +FRE+ + L HPNI++ EV+ T L +VMEYA+GGE+F+ + R Sbjct: 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRM 154 Query: 392 HEDEARYFFQQLVCGVSFC 448 E EAR F+Q+V V +C Sbjct: 155 KEKEARAKFRQIVSAVQYC 173
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 80.9 bits (198), Expect = 1e-15 Identities = 45/115 (39%), Positives = 68/115 (59%), Gaps = 4/115 (3%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 283 Y+ R +G GNF V KL R+R T+ VA+K I++ R+D E ++RE+ + L HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDSSNLEKIYREVQLMKLLNHPN 85 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 II+ +V+ T L IV E+A GE+F+ + E+EAR F Q++ V +C Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYC 140
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 80.5 bits (197), Expect = 2e-15 Identities = 45/115 (39%), Positives = 68/115 (59%), Gaps = 4/115 (3%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 283 Y+ R +G GNF V KL R+R T+ VA+K I++ R+D E ++RE+ + L HPN Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDSSNLEKIYREVQLMKLLNHPN 85 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 II+ +V+ T L IV E+A GE+F+ + E+EAR F Q++ V +C Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYC 140
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 79.3 bits (194), Expect = 4e-15 Identities = 45/121 (37%), Positives = 69/121 (57%), Gaps = 3/121 (2%) Frame = +2 Query: 95 ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID---ENVFREIVNHR 265 E+ + Y ++ IG GNF KL R+ T VA+K I++ + +FRE+ + Sbjct: 49 EQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK 108 Query: 266 SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 L HPNI++ EV+ T L ++MEYA+GGE+F+ + R E EAR F+Q+V V + Sbjct: 109 ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 168 Query: 446 C 448 C Sbjct: 169 C 169
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 79.3 bits (194), Expect = 4e-15 Identities = 45/121 (37%), Positives = 69/121 (57%), Gaps = 3/121 (2%) Frame = +2 Query: 95 ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID---ENVFREIVNHR 265 E+ + Y ++ IG GNF KL R+ T VA+K I++ + +FRE+ + Sbjct: 49 EQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK 108 Query: 266 SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 L HPNI++ EV+ T L ++MEYA+GGE+F+ + R E EAR F+Q+V V + Sbjct: 109 ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 168 Query: 446 C 448 C Sbjct: 169 C 169
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 78.6 bits (192), Expect = 7e-15 Identities = 44/115 (38%), Positives = 67/115 (58%), Gaps = 4/115 (3%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 283 Y+ R +G GNF V KL R+R T+ VA+K I++ R+D E ++RE+ + L HP+ Sbjct: 26 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDPSNLEKIYREVQIMKLLNHPH 84 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 II+ +V+ T L IV E+A GE+F+ + E EAR F Q++ V +C Sbjct: 85 IIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYC 139
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 78.6 bits (192), Expect = 7e-15 Identities = 43/115 (37%), Positives = 70/115 (60%), Gaps = 4/115 (3%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 283 Y+ +G GNF V KL R+R T+ VA+K I++ ++D E ++RE+ + L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKS-QLDAVNLEKIYREVQIMKMLDHPH 78 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 II+ +V+ T + L +V EYA GE+F+ + + R +E EAR F Q++ V +C Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYC 133
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 78.2 bits (191), Expect = 9e-15 Identities = 42/109 (38%), Positives = 63/109 (57%), Gaps = 4/109 (3%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIER----GYRIDENVFREIVNHRSLRHPNIIRFKE 301 +G G FG K+ + T+ VA+K + R + + REI N RHP+IIR + Sbjct: 93 LGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHIIRLYQ 152 Query: 302 VVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 V+ TP+ + ++ME+ +GGELF+ I R EAR FFQQ++ GV +C Sbjct: 153 VISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYC 201
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 78.2 bits (191), Expect = 9e-15 Identities = 44/115 (38%), Positives = 68/115 (59%), Gaps = 4/115 (3%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 283 Y+ R +G GNF V KL R+R T+ VA+K I++ R+D E ++RE+ + L HP+ Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKT-RLDSSNLEKIYREVQLMKLLNHPH 85 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 II+ +V+ T L IV E+A GE+F+ + E+EAR F Q++ V +C Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYC 140
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 77.8 bits (190), Expect = 1e-14 Identities = 43/115 (37%), Positives = 70/115 (60%), Gaps = 4/115 (3%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 283 Y+ +G GNF V KL R+R T+ VA+K I++ ++D E ++RE+ + L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKS-QLDAVNLEKIYREVQIMKMLDHPH 78 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 II+ +V+ T + L +V EYA GE+F+ + + R +E EAR F Q++ V +C Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYC 133
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 77.8 bits (190), Expect = 1e-14 Identities = 43/115 (37%), Positives = 70/115 (60%), Gaps = 4/115 (3%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPN 283 Y+ +G GNF V KL R+R T+ VA+K I++ ++D E ++RE+ + L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKS-QLDAVNLEKIYREVQIMKMLDHPH 78 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 II+ +V+ T + L +V EYA GE+F+ + + R +E EAR F Q++ V +C Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYC 133
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 77.0 bits (188), Expect = 2e-14 Identities = 44/116 (37%), Positives = 69/116 (59%), Gaps = 4/116 (3%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN----VFREIVNHRSLRHP 280 +Y+ ++ +G G+FG KL ++ T + VA+K I R + V REI R LRHP Sbjct: 51 RYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHP 110 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 +II+ +V+ + + +V+E+A G ELF+ I + EDEAR FFQQ++ V +C Sbjct: 111 HIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYC 165
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 76.6 bits (187), Expect = 3e-14 Identities = 46/118 (38%), Positives = 65/118 (55%), Gaps = 4/118 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG----YRIDENVFREIVNHRSLR 274 M +YE + +G G F R+ T + VA+K I++ + E + REI R LR Sbjct: 9 MLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLR 68 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 HPNI+ EV+ T + + VME+ GGELF ++ + ED AR +FQQLV V FC Sbjct: 69 HPNIVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYFQQLVRAVDFC 125
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 76.6 bits (187), Expect = 3e-14 Identities = 44/116 (37%), Positives = 69/116 (59%), Gaps = 4/116 (3%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN----VFREIVNHRSLRHP 280 +Y+ ++ +G G+FG KL ++ T + VA+K I R + V REI R LRHP Sbjct: 52 RYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHP 111 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 +II+ +V+ + + +V+E+A G ELF+ I + EDEAR FFQQ++ V +C Sbjct: 112 HIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYC 166
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 76.3 bits (186), Expect = 3e-14 Identities = 43/117 (36%), Positives = 63/117 (53%), Gaps = 5/117 (4%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER-----GYRIDENVFREIVNHRSLRH 277 KYE + +G G F R+R T + VA+K + + + N+ REI R L H Sbjct: 20 KYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSH 79 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 PNI++ EV+ T + + ME+ GGELF +I R ED +R +FQQL+ V +C Sbjct: 80 PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYC 136
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 75.1 bits (183), Expect = 8e-14 Identities = 44/120 (36%), Positives = 68/120 (56%), Gaps = 4/120 (3%) Frame = +2 Query: 101 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN----VFREIVNHRS 268 S + Y+ V+ +G G+FG KL + T + VA+K I + + + REI R Sbjct: 34 SRVGNYQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRL 93 Query: 269 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 LRHP+II+ +V+ + + +V+EYA G ELF+ I + E EAR FFQQ++ V +C Sbjct: 94 LRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVEYC 152
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 75.1 bits (183), Expect = 8e-14 Identities = 43/115 (37%), Positives = 66/115 (57%), Gaps = 4/115 (3%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN----VFREIVNHRSLRHPN 283 Y+ V+ +G G+FG KL + T + VA+K I + + + REI R LRHP+ Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 114 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 II+ +V+ + + +V+EYA G ELF+ I + E EAR FFQQ++ V +C Sbjct: 115 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYC 168
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 73.6 bits (179), Expect = 2e-13 Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 4/116 (3%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE----NVFREIVNHRSLRHP 280 +YE +G G +G K R + +VA+K I + DE ++ REI SL HP Sbjct: 54 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHP 113 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 +II EV + I+MEYA+ GEL++ I + R E E R+FF+Q+V V +C Sbjct: 114 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYC 169
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 73.6 bits (179), Expect = 2e-13 Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 4/116 (3%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE----NVFREIVNHRSLRHP 280 +YE +G G +G K R + +VA+K I + DE ++ REI SL HP Sbjct: 55 RYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHP 114 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 +II EV + I+MEYA+ GEL++ I + R E E R+FF+Q+V V +C Sbjct: 115 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYC 170
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 72.8 bits (177), Expect = 4e-13 Identities = 42/115 (36%), Positives = 64/115 (55%), Gaps = 2/115 (1%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSLRHP 280 ++ ++ V+ +G G +G +L NR T E VA+K ++ D EN+ +EI +R L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAADCPENIKKEICINRMLSHT 65 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 NI+RF + +EY GGELF+RI E +A+ FFQQL+ GV + Sbjct: 66 NIVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEY 120
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 72.8 bits (177), Expect = 4e-13 Identities = 42/112 (37%), Positives = 61/112 (54%), Gaps = 7/112 (6%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENVFREIVNHR---SLRHPNIIR 292 +G G F + ++ TR VA+K + R ++E REI R L HP+IIR Sbjct: 20 LGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRLFIDLIHPHIIR 79 Query: 293 FKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 EV++TP + +VMEY G+L + I + R EDEAR FQQ++ V +C Sbjct: 80 VYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVEYC 131
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 72.4 bits (176), Expect = 5e-13 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 8/126 (6%) Frame = +2 Query: 92 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE--------RGYRIDENVFR 247 R+ D YE E+GSG F + + R + T + A KFI+ RG +E + R Sbjct: 5 RQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREE-IER 63 Query: 248 EIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQL 427 E+ R +RHPNII ++ T + +++E +GGELF+ + + EDEA F +Q+ Sbjct: 64 EVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQI 123 Query: 428 VCGVSF 445 + GV + Sbjct: 124 LDGVHY 129
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 72.0 bits (175), Expect = 6e-13 Identities = 49/146 (33%), Positives = 76/146 (52%), Gaps = 14/146 (9%) Frame = +2 Query: 50 EIATHRKTSNR-SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR 226 E+ +K R R R ++ YE ++E+G G G KL R+ TREL+A+K I + R Sbjct: 112 EVKETKKIRKRFDRFSGRKYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTER 171 Query: 227 -----------IDENVFREIVNHRSLRHPNIIRFKEVVLTP--THLGIVMEYAAGGELFE 367 E V REI + HPN++R +EV+ P T + +V+EY +GGE+ Sbjct: 172 RPKLGRANASSQKEKVRREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPW 231 Query: 368 RICDAXRFHEDEARYFFQQLVCGVSF 445 CD+ EAR +F+ +V G+ + Sbjct: 232 TDCDSPVLSISEARQYFRDVVLGLEY 257
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 71.6 bits (174), Expect = 8e-13 Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 7/125 (5%) Frame = +2 Query: 92 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID-------ENVFRE 250 R+ + D Y+ E+GSG F V K R + T A KFI++ E++ RE Sbjct: 5 RQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIERE 64 Query: 251 IVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 + + +RHPN+I EV T + +++E AGGELF+ + + E+EA F +Q++ Sbjct: 65 VSILKEIRHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQIL 124 Query: 431 CGVSF 445 GV + Sbjct: 125 SGVYY 129
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 71.2 bits (173), Expect = 1e-12 Identities = 42/113 (37%), Positives = 64/113 (56%), Gaps = 3/113 (2%) Frame = +2 Query: 95 ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID---ENVFREIVNHR 265 E+ + Y ++ IG GNF KL R+ T VA+K I++ + +FRE+ + Sbjct: 49 EQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK 108 Query: 266 SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQ 424 L HPNI++ EV+ T L ++MEYA+GGE+F+ + R E EAR F+Q Sbjct: 109 ILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQ 161
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 71.2 bits (173), Expect = 1e-12 Identities = 40/115 (34%), Positives = 65/115 (56%), Gaps = 2/115 (1%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSLRHP 280 ++ ++ V+ +G G +G +L NR T E VA+K ++ D EN+ +EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAADCPENIKKEICINKMLNHE 65 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 N+++F + +EY +GGELF+RI E EA+ FFQQL+ GV + Sbjct: 66 NVVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVY 120
>NEK3_HUMAN (P51956) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) (HSPK 36) Length = 506 Score = 70.5 bits (171), Expect = 2e-12 Identities = 43/116 (37%), Positives = 64/116 (55%), Gaps = 4/116 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE--RGYRIDENVFREIVNHRSLRHP 280 MD Y +R IG G+FG A L+++ + ++ AMK I + + +N +E V ++HP Sbjct: 1 MDDYMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHP 60 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICD--AXRFHEDEARYFFQQLVCGVS 442 NI+ FKE HL IVMEY GG+L ++I F ED +F Q+ GV+ Sbjct: 61 NIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVN 116
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 70.5 bits (171), Expect = 2e-12 Identities = 42/126 (33%), Positives = 66/126 (52%), Gaps = 8/126 (6%) Frame = +2 Query: 92 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE--------RGYRIDENVFR 247 R+ D YE E+GSG F + + + + T A KFI+ RG +E + R Sbjct: 5 RQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREE-IER 63 Query: 248 EIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQL 427 E+ R +RHPNII +V T + +++E +GGELF+ + + EDEA F +Q+ Sbjct: 64 EVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQI 123 Query: 428 VCGVSF 445 + GV + Sbjct: 124 LDGVHY 129
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 70.5 bits (171), Expect = 2e-12 Identities = 42/126 (33%), Positives = 66/126 (52%), Gaps = 8/126 (6%) Frame = +2 Query: 92 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE--------RGYRIDENVFR 247 R+ D YE E+GSG F + + + + T A KFI+ RG +E + R Sbjct: 5 RQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREE-IER 63 Query: 248 EIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQL 427 E+ R +RHPNII +V T + +++E +GGELF+ + + EDEA F +Q+ Sbjct: 64 EVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQI 123 Query: 428 VCGVSF 445 + GV + Sbjct: 124 LDGVHY 129
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 69.7 bits (169), Expect = 3e-12 Identities = 39/113 (34%), Positives = 62/113 (54%), Gaps = 3/113 (2%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRHPNI 286 YE E+G G F + L N+ T++ A+K I E G ++N+ E+ + + HPNI Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNI 67 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 I KE+ TP L +VME GGELF++I + + E +A +++V V + Sbjct: 68 IALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGY 120
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 69.3 bits (168), Expect = 4e-12 Identities = 40/116 (34%), Positives = 71/116 (61%), Gaps = 5/116 (4%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE----NVFREIVNHRSLRHPN 283 Y+ + +G G+F V KL R+ T E VA+K I++ ++D ++F+E+ + ++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKT-KLDTLATGHLFQEVRCMKLVQHPN 74 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR-FHEDEARYFFQQLVCGVSFC 448 I+R EV+ T T L +++E GG++F+ I +ED A+ +F Q+V +S+C Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYC 130
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 69.3 bits (168), Expect = 4e-12 Identities = 40/116 (34%), Positives = 71/116 (61%), Gaps = 5/116 (4%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE----NVFREIVNHRSLRHPN 283 Y+ + +G G+F V KL R+ T E VA+K I++ ++D ++F+E+ + ++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKT-KLDTLATGHLFQEVRCMKLVQHPN 74 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR-FHEDEARYFFQQLVCGVSFC 448 I+R EV+ T T L +++E GG++F+ I +ED A+ +F Q+V +S+C Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYC 130
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 69.3 bits (168), Expect = 4e-12 Identities = 40/116 (34%), Positives = 71/116 (61%), Gaps = 5/116 (4%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE----NVFREIVNHRSLRHPN 283 Y+ + +G G+F V KL R+ T E VA+K I++ ++D ++F+E+ + ++HPN Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKT-KLDTLATGHLFQEVRCMKLVQHPN 74 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR-FHEDEARYFFQQLVCGVSFC 448 I+R EV+ T T L +++E GG++F+ I +ED A+ +F Q+V +S+C Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYC 130
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 69.3 bits (168), Expect = 4e-12 Identities = 40/125 (32%), Positives = 66/125 (52%), Gaps = 7/125 (5%) Frame = +2 Query: 92 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID-------ENVFRE 250 R+ + D Y+ E+GSG F V K R + T A KFI++ E++ RE Sbjct: 5 RQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIERE 64 Query: 251 IVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 + + ++HPN+I EV T + +++E AGGELF+ + + E+EA F +Q++ Sbjct: 65 VSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQIL 124 Query: 431 CGVSF 445 GV + Sbjct: 125 NGVYY 129
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 68.9 bits (167), Expect = 5e-12 Identities = 39/115 (33%), Positives = 65/115 (56%), Gaps = 2/115 (1%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSLRHP 280 ++ ++ V+ +G G +G +L NR T E VA+K ++ ID EN+ +EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCPENIKKEICINKMLNHE 65 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 N+++F + +EY +GGELF+RI E +A+ FF QL+ GV + Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVY 120
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 68.2 bits (165), Expect = 9e-12 Identities = 38/115 (33%), Positives = 65/115 (56%), Gaps = 2/115 (1%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSLRHP 280 ++ ++ V+ +G G +G +L NR T E VA+K ++ +D EN+ +EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHE 65 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 N+++F + +EY +GGELF+RI E +A+ FF QL+ GV + Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 120
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 67.8 bits (164), Expect = 1e-11 Identities = 39/115 (33%), Positives = 65/115 (56%), Gaps = 2/115 (1%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSLRHP 280 ++ ++ V+ +G G +G +L NR T E VA+K ++ ID EN+ +EI ++ L H Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCPENIKKEICINKMLSHE 65 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 N+++F + +EY +GGELF+RI E +A+ FF QL+ GV + Sbjct: 66 NVVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVY 120
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 67.8 bits (164), Expect = 1e-11 Identities = 47/131 (35%), Positives = 67/131 (51%), Gaps = 2/131 (1%) Frame = +2 Query: 59 THRKTSNRSRER-ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE 235 +HRK + R + + KY+ IG G+F + +R TR+ A+K IE YR Sbjct: 76 SHRKKVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREGR 135 Query: 236 NVFR-EIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARY 412 V E+ R +RH NII+ EV T + +VME A GGELF+RI F E +A Sbjct: 136 EVCESELCVLRRVRHTNIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATR 195 Query: 413 FFQQLVCGVSF 445 Q ++ GV + Sbjct: 196 VLQMVLDGVKY 206
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 67.4 bits (163), Expect = 2e-11 Identities = 42/119 (35%), Positives = 62/119 (52%), Gaps = 15/119 (12%) Frame = +2 Query: 134 IGSGNFGVAKLMRNR----------DTRELVAMKFIERG-----YRIDENVFREIVNHRS 268 +G G FG KL + D + VA+K I+R YR + ++REI + Sbjct: 47 LGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKH 106 Query: 269 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 L HPNI++ +EV+ ++GIV+EYA GGE ++ I R E A F QL+ GV + Sbjct: 107 LSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHY 165
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 67.0 bits (162), Expect = 2e-11 Identities = 41/109 (37%), Positives = 56/109 (51%), Gaps = 4/109 (3%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSLRHPNIIRFKE 301 IG G FG K + T VA+K + RG EI N + L HP+I R Sbjct: 30 IGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHPHITRLFR 89 Query: 302 VVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 V+ TP+ + +VME +GGELF I E+R +FQQ++ GVS+C Sbjct: 90 VISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYC 138
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 67.0 bits (162), Expect = 2e-11 Identities = 41/112 (36%), Positives = 63/112 (56%), Gaps = 2/112 (1%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-ERGYRIDEN-VFREIVNHRSLRHPNII 289 YE ++GSG F L + R + LVA+K I ++ R E V EI R + HPNI+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIV 74 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 ++V +P+HL + ME GGELF+RI + + E +A + Q++ VS+ Sbjct: 75 ALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSY 126
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 67.0 bits (162), Expect = 2e-11 Identities = 41/112 (36%), Positives = 63/112 (56%), Gaps = 2/112 (1%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-ERGYRIDEN-VFREIVNHRSLRHPNII 289 YE ++GSG F L + R + LVA+K I ++ R E V EI R + HPNI+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIV 74 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 ++V +P+HL + ME GGELF+RI + + E +A + Q++ VS+ Sbjct: 75 ALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSY 126
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 66.6 bits (161), Expect = 3e-11 Identities = 39/125 (31%), Positives = 67/125 (53%), Gaps = 4/125 (3%) Frame = +2 Query: 86 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVF----REI 253 R R + Y + +G G G+ KL + T + VA+K + R ++ E+V REI Sbjct: 40 RGRHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNRE-KLSESVLMKVEREI 98 Query: 254 VNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVC 433 + + HP++++ +V +L +V+E+ +GGELF+ + R EAR FF+Q+V Sbjct: 99 AILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVS 158 Query: 434 GVSFC 448 + FC Sbjct: 159 ALDFC 163
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 66.2 bits (160), Expect = 3e-11 Identities = 36/128 (28%), Positives = 64/128 (50%), Gaps = 7/128 (5%) Frame = +2 Query: 68 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR 247 K + + ++ G +E +R +G G FG ++ +DT+ + AMK + + + +N Sbjct: 395 KWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIA 454 Query: 248 EIVNHRSL-------RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEA 406 + R++ P I+ K TPT L +V +Y +GGELF + RF ED A Sbjct: 455 HTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRA 514 Query: 407 RYFFQQLV 430 +++ +LV Sbjct: 515 KFYIAELV 522
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 66.2 bits (160), Expect = 3e-11 Identities = 39/133 (29%), Positives = 67/133 (50%), Gaps = 7/133 (5%) Frame = +2 Query: 68 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR------- 226 ++ N +++ D Y+ E+GSG F + K R + T A KFI++ Sbjct: 7 RSPNMETFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV 66 Query: 227 IDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEA 406 E + RE+ R + HPNII +V T + +++E +GGELF+ + E+EA Sbjct: 67 CREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEA 126 Query: 407 RYFFQQLVCGVSF 445 F +Q++ GV++ Sbjct: 127 TSFIKQILDGVNY 139
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 66.2 bits (160), Expect = 3e-11 Identities = 41/112 (36%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-ERGYRIDEN-VFREIVNHRSLRHPNII 289 YE +GSG F L + R + LVA+K I ++ R E V EI R + HPNI+ Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIV 74 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 ++V +P+HL + ME GGELF+RI + + E +A + Q++ VS+ Sbjct: 75 ALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSY 126
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 66.2 bits (160), Expect = 3e-11 Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 18/123 (14%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVF------------------REIVN 259 +G G+ G +L RN T + A+K I + NV REI+ Sbjct: 25 LGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIII 84 Query: 260 HRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGV 439 + L HPN++R +V T T L +V+EYA GELF + + E EA FF+Q++ GV Sbjct: 85 MKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGV 144 Query: 440 SFC 448 S+C Sbjct: 145 SYC 147
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 65.9 bits (159), Expect = 5e-11 Identities = 41/114 (35%), Positives = 59/114 (51%), Gaps = 1/114 (0%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR-HPN 283 +D EP +G G+F V + R R + + A+K + R R++EN RE+ R + HPN Sbjct: 410 LDLREPA--LGQGSFSVCRRCRQRQSGQEFAVKILSR--RLEENTQREVAALRLCQSHPN 465 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 ++ EV+ H +V+E GGEL E I F E EA + LV VSF Sbjct: 466 VVNLHEVLHDQLHTYLVLELLRGGELLEHIRKKRLFSESEASQILRSLVSAVSF 519 Score = 40.8 bits (94), Expect = 0.002 Identities = 28/128 (21%), Positives = 59/128 (46%), Gaps = 9/128 (7%) Frame = +2 Query: 74 SNRSRERERSGMDKYEPVREIGSGNFGVAKLMRN---RDTRELVAMKFIERGYRIDENVF 244 +N + E+ ++ + ++ +G+G +G L+R D +L AMK + + + Sbjct: 19 ANLTGHEEKVSVENFALLKVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAALVQRAKT 78 Query: 245 REIVN-HRSL-----RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEA 406 +E RS+ + P ++ T L ++++Y +GGE+F + F E E Sbjct: 79 QEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEV 138 Query: 407 RYFFQQLV 430 R + ++V Sbjct: 139 RVYGGEIV 146
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 65.9 bits (159), Expect = 5e-11 Identities = 37/113 (32%), Positives = 65/113 (57%), Gaps = 1/113 (0%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR-EIVNHRSLRHPNI 286 D +E E+G G + + + T++ A+K +++ +D+ + R EI L HPNI Sbjct: 40 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--TVDKKIVRTEIGVLLRLSHPNI 97 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 I+ KE+ TPT + +V+E GGELF+RI + + E +AR +Q++ V++ Sbjct: 98 IKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAVAY 150
>NEK3_MOUSE (Q9R0A5) Serine/threonine-protein kinase Nek3 (EC 2.7.11.1)| (NimA-related protein kinase 3) Length = 511 Score = 64.7 bits (156), Expect = 1e-10 Identities = 42/114 (36%), Positives = 58/114 (50%), Gaps = 2/114 (1%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRHPNI 286 MD Y +R IG G+FG A L+ + + AMK I + +E V ++HPNI Sbjct: 1 MDNYTVLRVIGQGSFGRALLVLQESSNQTFAMKEIRLLKSDTQTSRKEAVLLAKMKHPNI 60 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICD--AXRFHEDEARYFFQQLVCGVS 442 + FKE +L IVMEY GG+L +RI F ED +F Q+ GV+ Sbjct: 61 VAFKESFEAEGYLYIVMEYCDGGDLMQRIKQQKGNLFPEDTILNWFIQICLGVN 114
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 64.7 bits (156), Expect = 1e-10 Identities = 36/115 (31%), Positives = 64/115 (55%), Gaps = 4/115 (3%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVF----REIVNHRSLRHPN 283 Y + +G G G+ KL + T + VA+K + R ++ E+V REI + + HP+ Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNRE-KLSESVLMKVEREIAILKLIEHPH 77 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 +++ +V +L +V+E+ +GGELF+ + R EAR FF+Q++ + FC Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFC 132
>SRK1_SCHPO (O94547) Serine/threonine-protein kinase srk1 (EC 2.7.11.1)| (Sty1-regulated kinase 1) Length = 580 Score = 64.7 bits (156), Expect = 1e-10 Identities = 40/128 (31%), Positives = 68/128 (53%), Gaps = 14/128 (10%) Frame = +2 Query: 104 GMDKYEPVREIGSGNFG-VAKLMRNRDTRELVAMKFIERGYRIDE-------------NV 241 G+++Y ++++G G F V K + NR T E VA+K ++R + N+ Sbjct: 120 GLEQYTLLQKMGDGAFSNVYKAIHNR-TGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNI 178 Query: 242 FREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQ 421 +E+ R ++HPNII+ E + TP + +V+E A GGELF +I F ED +R+ Sbjct: 179 LKEVQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVIT 238 Query: 422 QLVCGVSF 445 Q+ + + Sbjct: 239 QVAHAIRY 246
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 64.7 bits (156), Expect = 1e-10 Identities = 43/112 (38%), Positives = 59/112 (52%), Gaps = 1/112 (0%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR-EIVNHRSLRHPNII 289 KY+ IG G+F + +R TR+ A+K IE YR V E+ R +RH NII Sbjct: 96 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANII 155 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 + EV T + +VME A GGELF+RI F E +A Q ++ GV + Sbjct: 156 QLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRY 207
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 64.7 bits (156), Expect = 1e-10 Identities = 43/112 (38%), Positives = 59/112 (52%), Gaps = 1/112 (0%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR-EIVNHRSLRHPNII 289 KY+ IG G+F + +R TR+ A+K IE YR V E+ R +RH NII Sbjct: 96 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANII 155 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 + EV T + +VME A GGELF+RI F E +A Q ++ GV + Sbjct: 156 QLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRY 207
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 64.3 bits (155), Expect = 1e-10 Identities = 40/136 (29%), Positives = 68/136 (50%), Gaps = 16/136 (11%) Frame = +2 Query: 86 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-------------- 223 R++E + Y VR++GSG +G L R + A+K I++ Sbjct: 45 RKKEGKIGESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIEC 104 Query: 224 --RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE 397 +I E ++ EI +SL HPNII+ +V + +V E+ GGELFE+I + +F E Sbjct: 105 DDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDE 164 Query: 398 DEARYFFQQLVCGVSF 445 +A +Q++ G+ + Sbjct: 165 CDAANIMKQILSGICY 180
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 64.3 bits (155), Expect = 1e-10 Identities = 40/136 (29%), Positives = 68/136 (50%), Gaps = 16/136 (11%) Frame = +2 Query: 86 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-------------- 223 R++E + Y VR++GSG +G L R + A+K I++ Sbjct: 45 RKKEGKIGESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIEC 104 Query: 224 --RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE 397 +I E ++ EI +SL HPNII+ +V + +V E+ GGELFE+I + +F E Sbjct: 105 DDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDE 164 Query: 398 DEARYFFQQLVCGVSF 445 +A +Q++ G+ + Sbjct: 165 CDAANIMKQILSGICY 180
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 63.9 bits (154), Expect = 2e-10 Identities = 39/112 (34%), Positives = 61/112 (54%), Gaps = 2/112 (1%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE--NVFREIVNHRSLRHPNII 289 YE IG+G F KL + T E+VA+K +++ + V EI +SLRH +I Sbjct: 11 YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSDLPRVKTEIDALKSLRHQHIC 70 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 + V+ T + +V+EY GGELF+ I R E+E R F+Q++ V++ Sbjct: 71 QLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAY 122
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 63.9 bits (154), Expect = 2e-10 Identities = 32/118 (27%), Positives = 62/118 (52%), Gaps = 4/118 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR----IDENVFREIVNHRSLR 274 ++ +E R +G G FG L R R+++ ++A+K + + ++ + RE+ LR Sbjct: 137 LEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLR 196 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 HPNI+R + + ++++YA GGELF + RF + + + +QL + +C Sbjct: 197 HPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYC 254
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 63.9 bits (154), Expect = 2e-10 Identities = 32/119 (26%), Positives = 62/119 (52%), Gaps = 4/119 (3%) Frame = +2 Query: 86 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR 265 ++ E+ G+ +E + +G G+FG +R +DT E+ AMK + + + ++ N ++ R Sbjct: 110 KKSEKVGVADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSER 169 Query: 266 S----LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 + + HP ++ T L +++Y GGELF + +F ED RY+ ++V Sbjct: 170 NILQKINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIV 228
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 63.9 bits (154), Expect = 2e-10 Identities = 40/120 (33%), Positives = 63/120 (52%), Gaps = 6/120 (5%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENV----FREIVNHRSLR 274 M+KY + ++G G +G+ +NR+T E+VA+K I DE V REI + L+ Sbjct: 1 MEKYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSE-DEGVPCTAIREISLLKELK 59 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICD--AXRFHEDEARYFFQQLVCGVSFC 448 HPNI+R +V+ T L +V EY + ++ D + + F QL+ GV+FC Sbjct: 60 HPNIVRLHDVIHTERKLTLVFEYL--DQDLKKYLDECGGEISKPTIKSFMYQLLKGVAFC 117
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 63.9 bits (154), Expect = 2e-10 Identities = 32/118 (27%), Positives = 62/118 (52%), Gaps = 4/118 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR----IDENVFREIVNHRSLR 274 ++ +E R +G G FG L R R+++ ++A+K + + ++ + RE+ LR Sbjct: 137 LEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLR 196 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 HPNI+R + + ++++YA GGELF + RF + + + +QL + +C Sbjct: 197 HPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYC 254
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 63.9 bits (154), Expect = 2e-10 Identities = 38/134 (28%), Positives = 68/134 (50%), Gaps = 14/134 (10%) Frame = +2 Query: 86 RERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-------------- 223 R++E + Y VR++GSG +G L + ++ A+K I++ Sbjct: 46 RKKEGKIGESYFKVRKLGSGAYGEVLLCKEKNGHSEKAIKVIKKSQFDKGRYNDDNKNIE 105 Query: 224 RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE 403 + E ++ EI +SL HPNII+ +V + +V E+ GGELFE+I + +F E + Sbjct: 106 KFHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECD 165 Query: 404 ARYFFQQLVCGVSF 445 A +Q++ G+ + Sbjct: 166 AANIMKQILSGICY 179
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 63.5 bits (153), Expect = 2e-10 Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 1/106 (0%) Frame = +2 Query: 128 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR-HPNIIRFKEV 304 + +G G+F + + ++ + + A+K I + R++ N +EI + HPNI++ EV Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISK--RMEANTQKEITALKLCEGHPNIVKLHEV 487 Query: 305 VLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVS 442 H +VME GGELFERI F E EA Y ++LV VS Sbjct: 488 FHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVS 533 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/131 (25%), Positives = 68/131 (51%), Gaps = 10/131 (7%) Frame = +2 Query: 68 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMR---NRDTRELVAMKFIERGYRIDE- 235 +T+N + ER G++ +E ++ +G+G +G L+R DT +L AMK +++ + + Sbjct: 33 RTANLTGHAERVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKA 92 Query: 236 ------NVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE 397 R+++ H + + P ++ T T L ++++Y GGELF + RF E Sbjct: 93 KTTEHTRTERQVLEH-TRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTE 151 Query: 398 DEARYFFQQLV 430 E + + ++V Sbjct: 152 HEVQIYVGEIV 162
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 63.5 bits (153), Expect = 2e-10 Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 1/106 (0%) Frame = +2 Query: 128 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR-HPNIIRFKEV 304 + +G G+F + + ++ + + A+K I + R++ N +EI + HPNI++ EV Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISK--RMEANTQKEITALKLCEGHPNIVKLHEV 487 Query: 305 VLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVS 442 H +VME GGELFERI F E EA Y ++LV VS Sbjct: 488 FHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVS 533 Score = 55.1 bits (131), Expect = 8e-08 Identities = 33/131 (25%), Positives = 67/131 (51%), Gaps = 10/131 (7%) Frame = +2 Query: 68 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMR---NRDTRELVAMKFIERGYRIDE- 235 +T+N + E+ G++ +E ++ +G+G +G L+R DT +L AMK +++ + + Sbjct: 33 RTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKA 92 Query: 236 ------NVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE 397 R+++ H + P ++ T T L ++++Y GGELF + RF E Sbjct: 93 KTTEHTRTERQVLEH-IRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTE 151 Query: 398 DEARYFFQQLV 430 E + + ++V Sbjct: 152 HEVQIYVGEIV 162
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 63.5 bits (153), Expect = 2e-10 Identities = 36/113 (31%), Positives = 64/113 (56%), Gaps = 1/113 (0%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR-EIVNHRSLRHPNI 286 D +E E+G G + + + T++ A+K +++ +D+ + R EI L HPNI Sbjct: 40 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--TVDKKIVRTEIGVLLRLSHPNI 97 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 I+ KE+ TPT + +V+E GGELF+RI + + E +A +Q++ V++ Sbjct: 98 IKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAY 150
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 63.5 bits (153), Expect = 2e-10 Identities = 36/113 (31%), Positives = 64/113 (56%), Gaps = 1/113 (0%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR-EIVNHRSLRHPNI 286 D +E E+G G + + + T++ A+K +++ +D+ + R EI L HPNI Sbjct: 44 DFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--TVDKKIVRTEIGVLLRLSHPNI 101 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 I+ KE+ TPT + +V+E GGELF+RI + + E +A +Q++ V++ Sbjct: 102 IKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAY 154
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 63.5 bits (153), Expect = 2e-10 Identities = 43/147 (29%), Positives = 72/147 (48%), Gaps = 9/147 (6%) Frame = +2 Query: 32 SAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 211 SA +S+ T ++ R S DKY +E+G+G++ + K +N+ T + VA+K Sbjct: 172 SATSSQNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIF 231 Query: 212 ERGYRIDE---NVFREIVN-HRSLRHPNIIRFKEVVLTPTHLG-----IVMEYAAGGELF 364 D+ FRE N ++HPNI+ + + P +V+E GELF Sbjct: 232 HAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELF 291 Query: 365 ERICDAXRFHEDEARYFFQQLVCGVSF 445 ERI +DE++ F+QL+ G+ + Sbjct: 292 ERIVRKTCLRQDESKALFKQLLTGLKY 318
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 63.5 bits (153), Expect = 2e-10 Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 M++YE V +IG G +GV R+R T E +A+K I + + REI + ++H Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHED--EARYFFQQLVCGVSFC 448 NI+R ++VV + L +V EY +L + + + F +D + + F Q++CG+++C Sbjct: 61 RNIVRLQDVVHSEKRLYLVFEY-LDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYC 118
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 63.5 bits (153), Expect = 2e-10 Identities = 38/143 (26%), Positives = 71/143 (49%), Gaps = 6/143 (4%) Frame = +2 Query: 38 PASREIATHRKTSNR--SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI 211 PA E+AT +T+ + S R +D +E R +G G FG L R +++ +VA+K + Sbjct: 15 PAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVL 74 Query: 212 ERGY----RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICD 379 + ++ + REI L+HPNI+R + +++EYA GEL++ + Sbjct: 75 FKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQK 134 Query: 380 AXRFHEDEARYFFQQLVCGVSFC 448 + + E ++L +++C Sbjct: 135 SEKLDEQRTATIIEELADALTYC 157
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 63.2 bits (152), Expect = 3e-10 Identities = 38/125 (30%), Positives = 65/125 (52%), Gaps = 4/125 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 259 ++ + R M+++E V+ +G G FG L++ + T AMK +++ + + V + Sbjct: 139 AKPKHRVTMNEFEYVKLLGKGTFGKVILVKEKATAAYYAMKILKKEVIVAKDEVAHTLTE 198 Query: 260 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 +R L RHP++ K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 199 NRVLQNSRHPSLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 258 Query: 431 CGVSF 445 + + Sbjct: 259 SALDY 263
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 63.2 bits (152), Expect = 3e-10 Identities = 38/112 (33%), Positives = 61/112 (54%), Gaps = 2/112 (1%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE--NVFREIVNHRSLRHPNII 289 YE IG+G F KL + T E+VA+K +++ + + EI ++LRH +I Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHIC 70 Query: 290 RFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 + V+ T + +V+EY GGELF+ I R E+E R F+Q+V V++ Sbjct: 71 QLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAY 122
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 62.8 bits (151), Expect = 4e-10 Identities = 40/114 (35%), Positives = 57/114 (50%), Gaps = 1/114 (0%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR-HPN 283 +D EP +G G+F V + R R + + A+K + R R++ N RE+ R + HPN Sbjct: 410 LDLREPA--LGQGSFSVCRRCRQRQSGQEFAVKILSR--RLEANTQREVAALRLCQSHPN 465 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 ++ EV H +V+E GGEL E I F E EA + LV VSF Sbjct: 466 VVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSF 519 Score = 43.1 bits (100), Expect = 3e-04 Identities = 29/128 (22%), Positives = 60/128 (46%), Gaps = 9/128 (7%) Frame = +2 Query: 74 SNRSRERERSGMDKYEPVREIGSGNFGVAKLMRN---RDTRELVAMKFIERGYRIDENVF 244 +N + E+ ++ +E ++ +G+G +G L+R D +L AMK + + + Sbjct: 19 ANLTGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKT 78 Query: 245 REIVN-HRSL-----RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEA 406 +E RS+ + P ++ T L ++++Y +GGE+F + F E E Sbjct: 79 QEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEV 138 Query: 407 RYFFQQLV 430 R + ++V Sbjct: 139 RVYGGEIV 146
>STK36_HUMAN (Q9NRP7) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 62.8 bits (151), Expect = 4e-10 Identities = 40/116 (34%), Positives = 64/116 (55%), Gaps = 3/116 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE---NVFREIVNHRSLRH 277 M+KY + IG G+FG R + + ++VA+KFI + R ++ N+ REI R LRH Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 PNI+ + T + +V +YA GELF+ + D + ED+ + QLV + + Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYY 115
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 62.8 bits (151), Expect = 4e-10 Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 M++YE V +IG G +GV R+R T E +A+K I + + REI + ++H Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHED--EARYFFQQLVCGVSFC 448 NI+R ++VV + L +V EY +L + + + F +D + + F Q++CG+++C Sbjct: 61 RNIVRLQDVVHSEKRLYLVFEY-LDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYC 118
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 62.8 bits (151), Expect = 4e-10 Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 M++YE V +IG G +GV R+R T E +A+K I + + REI + ++H Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHED--EARYFFQQLVCGVSFC 448 NI+R ++VV + L +V EY +L + + + F +D + + F Q++CG+++C Sbjct: 61 RNIVRLQDVVHSEKRLYLVFEY-LDLDLKKFMDSSPEFAKDQRQIKMFLYQILCGIAYC 118
>KCC2_SCHPO (O42844) Calcium/calmodulin-dependent protein kinase type II (EC| 2.7.11.17) (CAM kinase II) Length = 504 Score = 62.4 bits (150), Expect = 5e-10 Identities = 40/125 (32%), Positives = 65/125 (52%), Gaps = 13/125 (10%) Frame = +2 Query: 104 GMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIVNHRSL 271 G++KY+ + +G G F + D +E VA+K I R Y ++ + VF+E+ R + Sbjct: 61 GLEKYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVI-RKYEMNKKQRQGVFKEVNIMRRV 119 Query: 272 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQL-------- 427 +H N++ + V T +VME A GGELF +I + F E+ AR+ Q+ Sbjct: 120 KHKNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEAVKHLH 179 Query: 428 -VCGV 439 VCG+ Sbjct: 180 DVCGI 184
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 62.0 bits (149), Expect = 7e-10 Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 7/116 (6%) Frame = +2 Query: 104 GMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR--- 274 G D + P++ IG G FG L+R +DT + AMK + + + V R + Sbjct: 262 GPDDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQT 321 Query: 275 ----HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 P I+ + TP L +V +Y AGGELF + + RF E+ A+++ +L+ Sbjct: 322 SAADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELL 377
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 62.0 bits (149), Expect = 7e-10 Identities = 33/105 (31%), Positives = 60/105 (57%), Gaps = 1/105 (0%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSLRHPNIIRFKEVVL 310 +GSG F L++ R T +L A+K I++ D ++ EI + ++H NI+ +++ Sbjct: 29 LGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYE 88 Query: 311 TPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 + TH +VM+ +GGELF+RI + + E +A QQ++ V + Sbjct: 89 STTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKY 133
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 62.0 bits (149), Expect = 7e-10 Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 8/134 (5%) Frame = +2 Query: 68 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE--------RGY 223 ++ N +++ D Y+ E+GSG F + K R + T A KFI+ RG Sbjct: 7 RSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV 66 Query: 224 RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE 403 +E + RE+ R + H N+I +V T + +++E +GGELF+ + E+E Sbjct: 67 SREE-IEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEE 125 Query: 404 ARYFFQQLVCGVSF 445 A F +Q++ GV++ Sbjct: 126 ATSFIKQILDGVNY 139
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 62.0 bits (149), Expect = 7e-10 Identities = 33/105 (31%), Positives = 60/105 (57%), Gaps = 1/105 (0%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSLRHPNIIRFKEVVL 310 +GSG F L++ R T +L A+K I++ D ++ EI + ++H NI+ +++ Sbjct: 29 LGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYE 88 Query: 311 TPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 + TH +VM+ +GGELF+RI + + E +A QQ++ V + Sbjct: 89 STTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKY 133
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 62.0 bits (149), Expect = 7e-10 Identities = 33/105 (31%), Positives = 60/105 (57%), Gaps = 1/105 (0%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSLRHPNIIRFKEVVL 310 +GSG F L++ R T +L A+K I++ D ++ EI + ++H NI+ +++ Sbjct: 29 LGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDIYE 88 Query: 311 TPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 + TH +VM+ +GGELF+RI + + E +A QQ++ V + Sbjct: 89 STTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKY 133
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 62.0 bits (149), Expect = 7e-10 Identities = 38/121 (31%), Positives = 64/121 (52%), Gaps = 5/121 (4%) Frame = +2 Query: 98 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSL- 271 R G+D +E +R +G G+FG L R ++T EL A+K +++ + D++V + R L Sbjct: 349 RFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILS 408 Query: 272 ---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVS 442 HP + + TP L VME+ GG+L I + RF E AR++ +++ + Sbjct: 409 LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALM 468 Query: 443 F 445 F Sbjct: 469 F 469
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 62.0 bits (149), Expect = 7e-10 Identities = 38/121 (31%), Positives = 64/121 (52%), Gaps = 5/121 (4%) Frame = +2 Query: 98 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSL- 271 R G+D +E +R +G G+FG L R ++T EL A+K +++ + D++V + R L Sbjct: 349 RFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILS 408 Query: 272 ---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVS 442 HP + + TP L VME+ GG+L I + RF E AR++ +++ + Sbjct: 409 LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALM 468 Query: 443 F 445 F Sbjct: 469 F 469
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 61.6 bits (148), Expect = 9e-10 Identities = 39/118 (33%), Positives = 65/118 (55%), Gaps = 2/118 (1%) Frame = +2 Query: 98 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--ENVFREIVNHRSL 271 R ++ + + +G G +G KL+ NR T E VAMK ++ D +V +E+ + L Sbjct: 16 REFVEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKML 75 Query: 272 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 + +I+RF + I +EYAAGGELF+RI + EA+ +F QL+ G+++ Sbjct: 76 QDKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNY 133
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 61.6 bits (148), Expect = 9e-10 Identities = 40/129 (31%), Positives = 64/129 (49%), Gaps = 10/129 (7%) Frame = +2 Query: 89 ERERSGMDKYEPVREIGSGNFGVAKL-----MRNRDTRELVAMKFIERGYRIDE-----N 238 +R+ + Y +G G FG KL + + + VA+K I R + Sbjct: 37 QRKHATFGPYIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIK 96 Query: 239 VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFF 418 ++REI + L HPNII +EV+ ++GIV+E+ +GGE ++ I R E A F Sbjct: 97 IYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLF 156 Query: 419 QQLVCGVSF 445 QL+ GV++ Sbjct: 157 AQLISGVNY 165
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 61.2 bits (147), Expect = 1e-09 Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 4/109 (3%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN----VFREIVNHRSLRHPNIIRFKE 301 +GSG ++L ++R+T +L +K I + + + E+V R + HPN+++ + Sbjct: 16 LGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPNVLQLID 75 Query: 302 VVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 V+ L +V+EY GGELF+ + F E + F Q++CG+ +C Sbjct: 76 VISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYC 124
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 61.2 bits (147), Expect = 1e-09 Identities = 37/121 (30%), Positives = 64/121 (52%), Gaps = 5/121 (4%) Frame = +2 Query: 98 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-RIDENVFREIVNHRSL- 271 R G+D +E +R +G G+FG L R ++T +L A+K +++ +D++V + R L Sbjct: 348 RLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILS 407 Query: 272 ---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVS 442 HP + + TP L VME+ GG+L I + RF E AR++ +++ + Sbjct: 408 LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALM 467 Query: 443 F 445 F Sbjct: 468 F 468
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 61.2 bits (147), Expect = 1e-09 Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 2/114 (1%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-RIDENVFR-EIVNHRSLRHPN 283 ++Y+ R IG GNF V K R T A+K I++ R E++ + E+ R ++HPN Sbjct: 81 ERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN 140 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 I+ E + PT L +VME GG+LF+ I ++ E +A L + + Sbjct: 141 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKY 194
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 61.2 bits (147), Expect = 1e-09 Identities = 40/142 (28%), Positives = 67/142 (47%), Gaps = 12/142 (8%) Frame = +2 Query: 59 THRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR---- 226 T T S + S + ++ +G G+ G +L ++ T A+K I + Sbjct: 2 TVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNG 61 Query: 227 --------IDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA 382 + N+ REIV + L HPN++ +V T +L +++EYA GELF + D Sbjct: 62 NHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDH 121 Query: 383 XRFHEDEARYFFQQLVCGVSFC 448 E EA F+Q++ G+S+C Sbjct: 122 GPLPEREAINCFRQIIIGISYC 143
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 61.2 bits (147), Expect = 1e-09 Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 2/114 (1%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-RIDENVFR-EIVNHRSLRHPN 283 ++Y+ R IG GNF V K R T A+K I++ R E++ + E+ R ++HPN Sbjct: 404 ERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN 463 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 I+ E + PT L +VME GG+LF+ I ++ E +A L + + Sbjct: 464 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKY 517
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 61.2 bits (147), Expect = 1e-09 Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 1/106 (0%) Frame = +2 Query: 128 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR-HPNIIRFKEV 304 + +G G+F + + ++ T + A+K I + R++ N REI + HPN+++ EV Sbjct: 420 KPLGEGSFSICRKCLHKKTSQEYAVKIISK--RMEANTQREITALKLCEGHPNVVKLHEV 477 Query: 305 VLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVS 442 H +VME GGEL ERI F E EA + ++LV VS Sbjct: 478 YHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRLVSAVS 523
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 60.8 bits (146), Expect = 1e-09 Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 2/114 (1%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY-RIDENVFR-EIVNHRSLRHPN 283 ++Y+ R IG GNF V K R T A+K I++ R E++ + E+ R ++HPN Sbjct: 388 ERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN 447 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 I+ E + PT L +VME GG+LF+ I ++ E +A L + + Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKY 501
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 60.8 bits (146), Expect = 1e-09 Identities = 37/127 (29%), Positives = 65/127 (51%), Gaps = 4/127 (3%) Frame = +2 Query: 77 NRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREI 253 + S+ + + M+++E ++ +G G FG L++ + T AMK +++ + + V + Sbjct: 138 SHSKPKHKVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTL 197 Query: 254 VNHRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQ 424 +R L RHP + K T L VMEYA GGELF + F ED AR++ + Sbjct: 198 TENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERIFSEDRARFYGAE 257 Query: 425 LVCGVSF 445 +V + + Sbjct: 258 IVSALDY 264
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 60.8 bits (146), Expect = 1e-09 Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 5/116 (4%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER----GYRID-ENVFREIVNHRSLRH 277 KY + +G+G FGV + +N +T E VA+K + + G ++ E ++ E+ + L H Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHH 95 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 PNI+ FK+ + I+ + A GGELF+RI +F E++A +++ V + Sbjct: 96 PNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKY 151
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 60.8 bits (146), Expect = 1e-09 Identities = 33/129 (25%), Positives = 64/129 (49%), Gaps = 4/129 (3%) Frame = +2 Query: 74 SNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENV 241 S S+ ++ +D +E R +G G FG L R + +R +VA+K + + ++ + Sbjct: 68 SQGSQNKQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQL 127 Query: 242 FREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQ 421 REI L+HPNI++ + +++EYA GEL++ + + F E + Sbjct: 128 RREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIME 187 Query: 422 QLVCGVSFC 448 +L +++C Sbjct: 188 ELSDALTYC 196
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 60.5 bits (145), Expect = 2e-09 Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 4/125 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 259 ++ + R M+++E ++ +G G FG L++ + T AMK +++ + + V + Sbjct: 139 AKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTE 198 Query: 260 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 +R L RHP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 199 NRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 258 Query: 431 CGVSF 445 + + Sbjct: 259 SALDY 263
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 60.5 bits (145), Expect = 2e-09 Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 4/125 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 259 ++ + R M+++E ++ +G G FG L++ + T AMK +++ + + V + Sbjct: 139 AKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTE 198 Query: 260 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 +R L RHP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 199 NRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 258 Query: 431 CGVSF 445 + + Sbjct: 259 SALDY 263
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 60.5 bits (145), Expect = 2e-09 Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 4/125 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 259 ++ + R M+++E ++ +G G FG L++ + T AMK +++ + + V + Sbjct: 139 AKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTE 198 Query: 260 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 +R L RHP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 199 NRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 258 Query: 431 CGVSF 445 + + Sbjct: 259 SALDY 263
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 60.5 bits (145), Expect = 2e-09 Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 3/116 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE---NVFREIVNHRSLRH 277 M+KY + IG G+FG R + + ++VA+KFI + R ++ N+ REI R LRH Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 PNI+ + T + +V +YA GEL + + D + ED+ + QLV + + Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAE-GELLQILEDDGKLPEDQVQAIAAQLVSALYY 115
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 60.5 bits (145), Expect = 2e-09 Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 4/125 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 259 ++ + R M+++E ++ +G G FG L++ + T AMK +++ + + V + Sbjct: 160 AKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTE 219 Query: 260 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 +R L RHP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 220 NRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 279 Query: 431 CGVSF 445 + + Sbjct: 280 SALDY 284
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 60.5 bits (145), Expect = 2e-09 Identities = 34/117 (29%), Positives = 62/117 (52%), Gaps = 4/117 (3%) Frame = +2 Query: 104 GMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR--- 274 G+D +E ++ +G G FG +R ++T E+ AMK + + + +++N + R + Sbjct: 130 GIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKI 189 Query: 275 -HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVS 442 HP I++ K T L +V+++ GG LF ++ F ED AR + ++V VS Sbjct: 190 DHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVS 246
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 60.5 bits (145), Expect = 2e-09 Identities = 30/117 (25%), Positives = 63/117 (53%), Gaps = 4/117 (3%) Frame = +2 Query: 92 RERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR-- 265 + +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + Sbjct: 35 QNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRI 94 Query: 266 --SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 ++ P ++R + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 95 LQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 60.5 bits (145), Expect = 2e-09 Identities = 33/126 (26%), Positives = 62/126 (49%), Gaps = 4/126 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENVFRE 250 S+ R+ +D +E R +G G FG L R + +R +VA+K + + ++ + RE Sbjct: 69 SQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRRE 128 Query: 251 IVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 I L+HPNI++ + +++EYA GEL++ + + F E ++L Sbjct: 129 IEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELS 188 Query: 431 CGVSFC 448 + +C Sbjct: 189 DALMYC 194
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 60.1 bits (144), Expect = 2e-09 Identities = 35/120 (29%), Positives = 62/120 (51%) Frame = +2 Query: 89 ERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRS 268 +R ++ + + + +G+G+ +L ++ T +L A+K I Y ++ EI+ R Sbjct: 3 KRHKNTIGVWRLGKTLGTGSTSCVRLAKHAKTGDLAAIKIIPIRYA---SIGMEILMMRL 59 Query: 269 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 LRHPNI+R +V H+ + +EY GELF I E EA ++ Q++ V+ C Sbjct: 60 LRHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHC 119
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 60.1 bits (144), Expect = 2e-09 Identities = 33/116 (28%), Positives = 62/116 (53%), Gaps = 4/116 (3%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLRH 277 D++E +R +G G+FG L+R+++T AMK + + + I+N + ++ Sbjct: 41 DQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDF 100 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 P +++ + ++L +VMEY GGE+F R+ RF E A ++ Q+V V + Sbjct: 101 PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQY 156
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 60.1 bits (144), Expect = 2e-09 Identities = 30/114 (26%), Positives = 62/114 (54%), Gaps = 4/114 (3%) Frame = +2 Query: 101 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 268 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 38 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 269 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 + P ++R + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 98 VNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 60.1 bits (144), Expect = 2e-09 Identities = 36/146 (24%), Positives = 72/146 (49%), Gaps = 7/146 (4%) Frame = +2 Query: 32 SAPASR---EIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAM 202 SAP + E+A+ +K N ++ + ++ +E R +G G FG L R + ++ ++A+ Sbjct: 104 SAPENNPEEELASKQK--NEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILAL 161 Query: 203 KFIERGYR----IDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFER 370 K + + ++ + RE+ LRHPNI+R T + +++EYA G ++ Sbjct: 162 KVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRE 221 Query: 371 ICDAXRFHEDEARYFFQQLVCGVSFC 448 + +F E + +L +S+C Sbjct: 222 LQKLSKFDEQRTATYITELANALSYC 247
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 60.1 bits (144), Expect = 2e-09 Identities = 30/114 (26%), Positives = 62/114 (54%), Gaps = 4/114 (3%) Frame = +2 Query: 101 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 268 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 85 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 144 Query: 269 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 + P ++R + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 145 VNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 198
>STK36_MOUSE (Q69ZM6) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1268 Score = 59.7 bits (143), Expect = 3e-09 Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 3/116 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDE---NVFREIVNHRSLRH 277 M+KY + IG G+FG R + + ++VA+KFI + R ++ N+ REI R L H Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLWH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 PNI+ + T + +V +YA GELF+ + D + ED+ + QLV + + Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYY 115
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 59.7 bits (143), Expect = 3e-09 Identities = 34/117 (29%), Positives = 61/117 (52%), Gaps = 4/117 (3%) Frame = +2 Query: 104 GMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR--- 274 G++ +E ++ +G G FG +R +DT E+ AMK + + +++N + R + Sbjct: 136 GIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKI 195 Query: 275 -HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVS 442 HP I++ K T L +V+++ GG LF ++ F ED AR + ++V VS Sbjct: 196 DHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVS 252
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 59.7 bits (143), Expect = 3e-09 Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 5/111 (4%) Frame = +2 Query: 128 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENV-----FREIVNHRSLRHPNIIR 292 R +G+G+FGV + R T E VA+K + + NV + E+ + L HPNI+ Sbjct: 51 RTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVS 110 Query: 293 FKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 FK+ + IV + A GGELF+RI +F E +A Q++ V + Sbjct: 111 FKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEY 161
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 59.3 bits (142), Expect = 4e-09 Identities = 34/99 (34%), Positives = 55/99 (55%), Gaps = 2/99 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN--VFREIVNHRSLRHP 280 ++KY+ + IG GNF V K +R T + A+K I++ + + E+ R ++HP Sbjct: 391 LEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHP 450 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE 397 NII E + T T L +VME GG+LF+ I + ++ E Sbjct: 451 NIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTE 489
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 59.3 bits (142), Expect = 4e-09 Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 4/125 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNH 262 S+ R + M+ ++ ++ +G G FG L+R + T AMK + + I ++ V Sbjct: 141 SKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTE 200 Query: 263 ----RSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 ++ RHP + K T L VMEYA GG+LF + F ED AR++ ++V Sbjct: 201 SRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIV 260 Query: 431 CGVSF 445 + + Sbjct: 261 SALEY 265
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 59.3 bits (142), Expect = 4e-09 Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 4/125 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNH 262 ++ R + M+ ++ ++ +G G FG L+R + T AMK + + I ++ V Sbjct: 141 NKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTE 200 Query: 263 ----RSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 ++ RHP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 201 SRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIV 260 Query: 431 CGVSF 445 + + Sbjct: 261 SALEY 265
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 59.3 bits (142), Expect = 4e-09 Identities = 38/143 (26%), Positives = 67/143 (46%), Gaps = 4/143 (2%) Frame = +2 Query: 29 CSAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKF 208 C +P+ + + S+ R + M+ ++ ++ +G G FG L+R + T AMK Sbjct: 124 CGSPSDSSTTEEMEVAV-SKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKI 182 Query: 209 IERGYRIDENVFREIVNH----RSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERIC 376 + + I ++ V ++ RHP + K T L VMEYA GGELF + Sbjct: 183 LRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLS 242 Query: 377 DAXRFHEDEARYFFQQLVCGVSF 445 F E+ AR++ ++V + + Sbjct: 243 RERVFTEERARFYGAEIVSALEY 265
>ATG1_NEUCR (Q7RX99) Serine/threonine-protein kinase atg-1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 932 Score = 59.3 bits (142), Expect = 4e-09 Identities = 33/104 (31%), Positives = 59/104 (56%), Gaps = 3/104 (2%) Frame = +2 Query: 59 THRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY---RI 229 T +S+R ++ + + +EIG G+F L R++ T LVA+K +E ++ Sbjct: 5 TSASSSSRRTKQNYDAIGSFVIDQEIGKGSFAKVYLGRHKVTGALVAVKSVELARLNKKL 64 Query: 230 DENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGEL 361 EN++ EI ++LRHP+I+ + V + TH+ ++MEY G+L Sbjct: 65 KENLYGEIQILKTLRHPHIVALHDCVESSTHINLIMEYCELGDL 108
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 59.3 bits (142), Expect = 4e-09 Identities = 30/114 (26%), Positives = 62/114 (54%), Gaps = 4/114 (3%) Frame = +2 Query: 101 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 268 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 38 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 269 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 + P ++R + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 98 VEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 59.3 bits (142), Expect = 4e-09 Identities = 30/114 (26%), Positives = 62/114 (54%), Gaps = 4/114 (3%) Frame = +2 Query: 101 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 268 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 38 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 269 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 + P ++R + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 98 VEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 59.3 bits (142), Expect = 4e-09 Identities = 30/114 (26%), Positives = 62/114 (54%), Gaps = 4/114 (3%) Frame = +2 Query: 101 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 268 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 38 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 269 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 + P ++R + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 98 VEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 59.3 bits (142), Expect = 4e-09 Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 M KY+ + +IG G +G RNRDT E+VA+K + E + + REI + L+H Sbjct: 1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEA--RYFFQQLVCGVSFC 448 NI+R +V+ + L +V E+ + ++ D+ D A R F QL+ G++FC Sbjct: 61 KNIVRLIDVLHSDKKLTLVFEHC--DQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFC 117
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 58.9 bits (141), Expect = 6e-09 Identities = 44/131 (33%), Positives = 66/131 (50%), Gaps = 7/131 (5%) Frame = +2 Query: 74 SNRSRERERSGMD-----KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER--GYRID 232 SNR ++ R D KY+ IG GNF + +R T++ A+K I+R G + Sbjct: 61 SNRKVKKYRDKFDPRVTAKYDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDRVQGKEVF 120 Query: 233 ENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARY 412 E+ E+ R ++H II+ EV T + +VME A GGELF+RI F E +A Sbjct: 121 ES---EVAVLRRVKHSYIIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATR 177 Query: 413 FFQQLVCGVSF 445 ++ GV + Sbjct: 178 VLNMVLDGVKY 188
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 58.9 bits (141), Expect = 6e-09 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 6/120 (5%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID---ENVFREIVNHRSLRH 277 MD ++ V +IG G +GV +NR+T +LVA+K I ++ REI + L+H Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE---DEARYFFQQLVCGVSFC 448 PNI+R +VV L +V E+ + + ++ D+ E + + QL+ GVSFC Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLS--QDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 58.9 bits (141), Expect = 6e-09 Identities = 32/111 (28%), Positives = 56/111 (50%) Frame = +2 Query: 95 ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLR 274 E + + Y+ +++IG G+FG L +R T V +K ++ D N+ RE+ HR Sbjct: 34 ELTEVGNYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKN---DPNIVREVFYHRQFD 90 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQL 427 P I + EV++T + + + +EY G EL++ + R E F Q+ Sbjct: 91 FPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQI 141
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 58.9 bits (141), Expect = 6e-09 Identities = 30/114 (26%), Positives = 62/114 (54%), Gaps = 4/114 (3%) Frame = +2 Query: 101 SGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----S 268 +G++ +E + +G+G+FG L++++ T + AMK +++ + +N + + Sbjct: 38 AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 269 LRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 + P ++R + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 98 VNFPFLVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 58.9 bits (141), Expect = 6e-09 Identities = 29/112 (25%), Positives = 62/112 (55%), Gaps = 4/112 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 274 +D++E ++ +G+G+FG L+++++T AMK +++ + +N + ++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 P +++ + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 100 FPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 58.5 bits (140), Expect = 7e-09 Identities = 34/118 (28%), Positives = 62/118 (52%), Gaps = 5/118 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVNHRSL---- 271 +D + + +G G+FG L RDT A+K +++ + D++V ++ + L Sbjct: 312 VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGT 371 Query: 272 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 +HP + T +HL VMEY GG+L I ++ RF E+ AR++ +++ G+ F Sbjct: 372 KHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKF 429
>NEK1_MOUSE (P51954) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) Length = 1203 Score = 58.5 bits (140), Expect = 7e-09 Identities = 37/112 (33%), Positives = 61/112 (54%), Gaps = 5/112 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID---ENVFREIVNHRSLRH 277 M+KY +++IG G+FG A L+++ + +K I D + RE+ +++H Sbjct: 1 MEKYVRLQKIGEGSFGKAVLVKSTEDGRHYVIKEINISRMSDKERQESRREVAVLANMKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERI--CDAXRFHEDEARYFFQQL 427 PNI+++KE L IVM+Y GG+LF+RI F ED+ +F Q+ Sbjct: 61 PNIVQYKESFEENGSLYIVMDYCEGGDLFKRINAQKGALFQEDQILDWFVQI 112
>ATG1_COLLN (P87248) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Colletotrichum lindemuthianum kinase 1) Length = 675 Score = 58.5 bits (140), Expect = 7e-09 Identities = 45/158 (28%), Positives = 72/158 (45%), Gaps = 27/158 (17%) Frame = +2 Query: 53 IATHRKTSNRSRERERSG---MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY 223 +A TS S R R G + ++ EIG G+F +++++ VA+K +E G Sbjct: 1 MADRLPTSTSSGRRRRDGDASIGEFVIGGEIGKGSFAQVYSGHHKNSKAAVAIKSVEMGR 60 Query: 224 ---RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR-- 388 ++ EN++ EI ++LRHP+I+ + V + TH+ +VMEY G+L I R Sbjct: 61 LNNKLRENLYGEIQILKTLRHPHIVALHDCVESATHINLVMEYCELGDLSFFIKKRDRHG 120 Query: 389 -------------------FHEDEARYFFQQLVCGVSF 445 HE R+F QQL + F Sbjct: 121 TNAATEDMARKYPVTPGSGLHEVVTRHFLQQLASALKF 158
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 58.5 bits (140), Expect = 7e-09 Identities = 38/144 (26%), Positives = 71/144 (49%), Gaps = 8/144 (5%) Frame = +2 Query: 38 PASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER 217 P ++E + + E G+ ++P++ +GSG+ G L+ + T EL AMK +E+ Sbjct: 551 PHNKESTSWKAIKKIQASGETVGLHHFKPIKPLGSGDTGSVHLVELKGTGELYAMKAMEK 610 Query: 218 GYRIDEN------VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERI-- 373 ++ N + REI++ L HP + T TH+ ++ ++ GGELF + Sbjct: 611 TMMLNRNKAHRACIEREIIS--LLDHPFLPTLYASFQTSTHVCLITDFCPGGELFALLDR 668 Query: 374 CDAXRFHEDEARYFFQQLVCGVSF 445 ED AR++ ++V G+ + Sbjct: 669 QPMKILTEDSARFYAAEVVIGLEY 692
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 58.5 bits (140), Expect = 7e-09 Identities = 29/112 (25%), Positives = 62/112 (55%), Gaps = 4/112 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 274 +D++E ++ +G+G+FG L+++++T AMK +++ + +N + ++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 P +++ + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 58.5 bits (140), Expect = 7e-09 Identities = 29/112 (25%), Positives = 62/112 (55%), Gaps = 4/112 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 274 +D++E ++ +G+G+FG L+++++T AMK +++ + +N + ++ Sbjct: 39 LDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVN 98 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 P +++ + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 99 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 150
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 58.5 bits (140), Expect = 7e-09 Identities = 36/119 (30%), Positives = 63/119 (52%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 M++YE V +IG G +GV R+R T E +A+K I + + REI + ++H Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE--ARYFFQQLVCGVSFC 448 NI+R ++VV + L +V EY +L + + F +D + F Q++ G+++C Sbjct: 61 GNIVRLQDVVHSEKRLYLVFEY-LDLDLKKHMDSCPEFSQDPRLVKMFLYQILRGIAYC 118
>ST32A_MOUSE (Q8BGW6) Serine/threonine-protein kinase 32A (EC 2.7.11.1)| Length = 398 Score = 58.2 bits (139), Expect = 9e-09 Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 4/123 (3%) Frame = +2 Query: 89 ERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIV 256 E E D +E +R IG G+FG ++R DT+++ AMK++ + ++ NVF+E+ Sbjct: 14 ENEDVNFDHFEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQ 73 Query: 257 NHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCG 436 + L HP ++ + +V++ GG+L + F ED + F +L Sbjct: 74 IMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELAMA 133 Query: 437 VSF 445 + + Sbjct: 134 LDY 136
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 58.2 bits (139), Expect = 9e-09 Identities = 38/119 (31%), Positives = 60/119 (50%), Gaps = 9/119 (7%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID--------ENVFREIVNHRSL 271 Y REIG+G F +L + D ++ A+KF+ + + + EI H+ Sbjct: 10 YHIGREIGTGAFASVRLCYD-DNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLC 68 Query: 272 R-HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 H NII F P +V+E+A GG+LF++I ED A+++F QL+ G+SF Sbjct: 69 NGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISF 127
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 57.8 bits (138), Expect = 1e-08 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 7/121 (5%) Frame = +2 Query: 89 ERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRS 268 E R G + + +R IG G FG L+R DT + AMK I + + + + R+ Sbjct: 293 EHVRYGPEDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERN 352 Query: 269 L-------RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQL 427 + P I+ K T + L ++ +Y +GGELF + RF E A+++ +L Sbjct: 353 ILVRTSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAEL 412 Query: 428 V 430 V Sbjct: 413 V 413
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 57.8 bits (138), Expect = 1e-08 Identities = 36/116 (31%), Positives = 66/116 (56%), Gaps = 3/116 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG-YRIDENV-FREIVNHRSLRHP 280 M++Y +R++G G +G + ++ ++ ELVA+K ++R Y DE + RE+ + + L H Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 60 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR-FHEDEARYFFQQLVCGVSF 445 N+I+ KEV+ HL + EY L++ + D + F E R Q++ G++F Sbjct: 61 NVIKLKEVIRENDHLYFIFEYMK-ENLYQLMKDRNKLFPESVIRNIMYQILQGLAF 115
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 57.8 bits (138), Expect = 1e-08 Identities = 36/119 (30%), Positives = 62/119 (52%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 M KYE + +IG G +G +NRDT E+VA+K + + + + REI + L+H Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE--ARYFFQQLVCGVSFC 448 NI+R +V+ + L +V E+ + ++ D+ D + F QL+ G++FC Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFC--DQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFC 117
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 57.8 bits (138), Expect = 1e-08 Identities = 27/126 (21%), Positives = 65/126 (51%), Gaps = 4/126 (3%) Frame = +2 Query: 80 RSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVN 259 R + +D +E ++ +G+G+FG +++++ T++ AMK +++ + +N Sbjct: 33 RRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLN 92 Query: 260 HR----SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQL 427 + +++ P ++ + ++L +V+EY GGE+F + RF E +R++ Q+ Sbjct: 93 EKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQI 152 Query: 428 VCGVSF 445 V + Sbjct: 153 VLAFEY 158
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 57.8 bits (138), Expect = 1e-08 Identities = 34/116 (29%), Positives = 64/116 (55%), Gaps = 3/116 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENV--FREIVNHRSLRHP 280 M++Y +R++G G +G L R+ ++ EL+A+K ++R + E RE+ + + L H Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR-FHEDEARYFFQQLVCGVSF 445 N+++ KEV+ HL + EY L++ I + + F E R Q++ G++F Sbjct: 61 NVVKLKEVIRENDHLYFIFEYMK-ENLYQLIKERNKLFPESAIRNIMYQILQGLAF 115
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 57.8 bits (138), Expect = 1e-08 Identities = 36/116 (31%), Positives = 66/116 (56%), Gaps = 3/116 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG-YRIDENV-FREIVNHRSLRHP 280 M++Y +R++G G +G + ++ ++ ELVA+K ++R Y DE + RE+ + + L H Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 60 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR-FHEDEARYFFQQLVCGVSF 445 N+I+ KEV+ HL + EY L++ + D + F E R Q++ G++F Sbjct: 61 NVIKLKEVIRENDHLYFIFEYMK-ENLYQLMKDRNKLFPESVIRNIMYQILQGLAF 115
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 57.8 bits (138), Expect = 1e-08 Identities = 28/112 (25%), Positives = 63/112 (56%), Gaps = 4/112 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 274 +D+++ ++ +G+G+FG L++++++ AMK +++ + +N + ++ Sbjct: 40 LDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 P +++ + ++L +VMEY AGGE+F + RF E AR++ Q+V Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 57.4 bits (137), Expect = 2e-08 Identities = 39/116 (33%), Positives = 65/116 (56%), Gaps = 6/116 (5%) Frame = +2 Query: 119 EPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENV----FREIVNHRSLRHPNI 286 E V +IG G +GV R+R T E +A+K I R + DE V REI + ++H NI Sbjct: 2 ENVEKIGEGTYGVVYKARDRVTNETIALKKI-RLEQEDEGVPSTAIREISLLKEMQHRNI 60 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHED--EARYFFQQLVCGVSFC 448 +R ++VV + L +V EY +L + + + F +D + + F Q++CG+++C Sbjct: 61 VRLQDVVHSDKRLYLVFEY-LDLDLKKHMDSSPEFIKDPRQVKMFLYQMLCGIAYC 115
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 57.4 bits (137), Expect = 2e-08 Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 4/125 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 259 S+ R + M+ ++ ++ +G G FG L+R + T AMK + + I + V + Sbjct: 145 SKGRPKVTMNDFDYLKLLGKGTFGKVILVREKATGLYYAMKILRKEVIIAKDEVAHTLTE 204 Query: 260 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 R L +HP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 205 SRVLQNTKHPFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIV 264 Query: 431 CGVSF 445 + + Sbjct: 265 SALEY 269
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 57.4 bits (137), Expect = 2e-08 Identities = 42/174 (24%), Positives = 76/174 (43%), Gaps = 39/174 (22%) Frame = +2 Query: 44 SREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER-- 217 S+ +T + S+ + R + ++ + +G G+ G +L +N +T +L A+K + + Sbjct: 57 SQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKK 116 Query: 218 ----------------GYRIDENVF---------------------REIVNHRSLRHPNI 286 + NV REIV + + H N+ Sbjct: 117 AFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNV 176 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 + EV + L +V+EY GGELF+ + + E EA ++F+Q+V GVS+C Sbjct: 177 MALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYC 230
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 57.4 bits (137), Expect = 2e-08 Identities = 33/140 (23%), Positives = 69/140 (49%), Gaps = 4/140 (2%) Frame = +2 Query: 41 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 220 + +E A+ +KT + + + ++ ++ R +G G FG L R R ++ ++A+K + + Sbjct: 101 SEKEQASLQKTEDTKKRQWT--LEDFDIGRPLGKGKFGNVYLARERQSKFILALKVLFKT 158 Query: 221 Y----RIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR 388 ++ + RE+ LRHPNI+R T + +++EYA G ++ + + Sbjct: 159 QLEKANVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK 218 Query: 389 FHEDEARYFFQQLVCGVSFC 448 F E + +L +S+C Sbjct: 219 FDEQRTATYITELANALSYC 238
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 2/99 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN--VFREIVNHRSLRHP 280 ++KY + IG GNF V K +R T + A+K I++ + + E+ R ++HP Sbjct: 390 LEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHP 449 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE 397 NII E + T T L +VME GG+LF+ I + ++ E Sbjct: 450 NIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTE 488
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 57.4 bits (137), Expect = 2e-08 Identities = 29/112 (25%), Positives = 61/112 (54%), Gaps = 4/112 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 274 +D++E ++ +G+G+FG L+++ +T AMK +++ + +N + ++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 P +++ + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 57.4 bits (137), Expect = 2e-08 Identities = 29/112 (25%), Positives = 61/112 (54%), Gaps = 4/112 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 274 +D++E ++ +G+G+FG L+++ +T AMK +++ + +N + ++ Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 P +++ + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 57.4 bits (137), Expect = 2e-08 Identities = 33/116 (28%), Positives = 64/116 (55%), Gaps = 4/116 (3%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY---RID-ENVFREIVNHRSLRH 277 ++Y+ ++ +G G+FG L R++ T A+K I + + + D E++ RE+ + L H Sbjct: 67 EQYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDH 126 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 NI++ E + +V + GGELF+ I RF+E +A +Q++ G+++ Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITY 182
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 57.4 bits (137), Expect = 2e-08 Identities = 36/134 (26%), Positives = 70/134 (52%), Gaps = 3/134 (2%) Frame = +2 Query: 53 IATHRKTSNRSRERERSGMDKYEPVRE-IGSGNFGVAKLMRNRDTRELVAMKFIERGYRI 229 +A S+ S +++ + K +E +G+G F L + T +L A+K I + Sbjct: 1 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK 60 Query: 230 --DENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE 403 + ++ EI R ++H NI+ +++ +P HL +VM+ +GGELF+RI + + E + Sbjct: 61 GKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKD 120 Query: 404 ARYFFQQLVCGVSF 445 A +Q++ V + Sbjct: 121 ASTLIRQVLDAVYY 134
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 57.4 bits (137), Expect = 2e-08 Identities = 36/134 (26%), Positives = 70/134 (52%), Gaps = 3/134 (2%) Frame = +2 Query: 53 IATHRKTSNRSRERERSGMDKYEPVRE-IGSGNFGVAKLMRNRDTRELVAMKFIERGYRI 229 +A S+ S +++ + K +E +G+G F L + T +L A+K I + Sbjct: 1 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK 60 Query: 230 --DENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE 403 + ++ EI R ++H NI+ +++ +P HL +VM+ +GGELF+RI + + E + Sbjct: 61 GKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKD 120 Query: 404 ARYFFQQLVCGVSF 445 A +Q++ V + Sbjct: 121 ASTLIRQVLDAVYY 134
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 57.0 bits (136), Expect = 2e-08 Identities = 34/116 (29%), Positives = 64/116 (55%), Gaps = 3/116 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVF--REIVNHRSLRHP 280 M++Y ++++G G +G L R+ ++ EL+A+K ++R + E RE+ + + L H Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR-FHEDEARYFFQQLVCGVSF 445 NI++ KEV+ HL + EY L++ I + + F E R Q++ G++F Sbjct: 61 NIVKLKEVIRENDHLYFIFEYMK-ENLYQLIKERNKLFPESAIRNIMYQILQGLAF 115
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 57.0 bits (136), Expect = 2e-08 Identities = 34/116 (29%), Positives = 64/116 (55%), Gaps = 3/116 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVF--REIVNHRSLRHP 280 M++Y ++++G G +G L R+ ++ EL+A+K ++R + E RE+ + + L H Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR-FHEDEARYFFQQLVCGVSF 445 NI++ KEV+ HL + EY L++ I + + F E R Q++ G++F Sbjct: 61 NIVKLKEVIRENDHLYFIFEYMK-ENLYQLIKERNKLFPESAIRNIMYQILQGLAF 115
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 57.0 bits (136), Expect = 2e-08 Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 3/100 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMK-FIER--GYRIDENVFREIVNHRSLRH 277 M+KYE + +IG G++GV RNRDT ++VA+K F+E I + REI + L+H Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE 397 PN++ EV L +V EY CD HE Sbjct: 61 PNLVNLLEVFRRKRRLHLVFEY----------CDHTVLHE 90
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 57.0 bits (136), Expect = 2e-08 Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 3/100 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAM-KFIER--GYRIDENVFREIVNHRSLRH 277 M+KYE + +IG G++GV RNRDT ++VA+ KF+E I + REI + L+H Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE 397 PN++ EV L +V EY CD HE Sbjct: 61 PNLVNLLEVFRRKRRLHLVFEY----------CDHTVLHE 90
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 57.0 bits (136), Expect = 2e-08 Identities = 37/125 (29%), Positives = 60/125 (48%), Gaps = 4/125 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DENVFREIVN 259 S+ + M+ ++ ++ +G G FG L+R + T AMK + + I + V + Sbjct: 146 SKGHPKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTLTE 205 Query: 260 HRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 R L +HP + K T L VMEYA GGELF + F ED AR++ ++V Sbjct: 206 SRVLQNTKHPFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIV 265 Query: 431 CGVSF 445 + + Sbjct: 266 SALEY 270
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 57.0 bits (136), Expect = 2e-08 Identities = 33/128 (25%), Positives = 67/128 (52%), Gaps = 4/128 (3%) Frame = +2 Query: 74 SNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID-ENVFRE 250 ++ + +R++ M+ ++ ++ +G G FG L + + T++L A+K +++ I E V Sbjct: 179 TSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHT 238 Query: 251 IVNHRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQ 421 + +R L +HP + K +L VM++A GGELF + F E AR++ Sbjct: 239 LTENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGA 298 Query: 422 QLVCGVSF 445 ++V + + Sbjct: 299 EIVLALGY 306
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 57.0 bits (136), Expect = 2e-08 Identities = 36/116 (31%), Positives = 66/116 (56%), Gaps = 3/116 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG-YRIDENV-FREIVNHRSLRHP 280 M++Y ++++G G +G + ++ ++ ELVA+K ++R Y DE + RE+ + + L H Sbjct: 1 MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 60 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR-FHEDEARYFFQQLVCGVSF 445 N+I+ KEV+ HL V EY L++ + D + F E R Q++ G++F Sbjct: 61 NVIKLKEVIRENDHLYFVFEYMK-ENLYQLMKDRNKLFPESVIRNIMYQILQGLAF 115
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 57.0 bits (136), Expect = 2e-08 Identities = 29/120 (24%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = +2 Query: 83 SRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNH 262 S + + +D ++ ++ +G+G+FG L+++++T AMK +++ + +N Sbjct: 32 SPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 91 Query: 263 R----SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 + ++ P +++ + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 92 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 56.6 bits (135), Expect = 3e-08 Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 5/112 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE---RGYRIDENVFREIVNHRSLRH 277 M+KY +++IG G+FG A L+++ + +K I + E RE+ +++H Sbjct: 1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERI--CDAXRFHEDEARYFFQQL 427 PNI++++E L IVM+Y GG+LF+RI F ED+ +F Q+ Sbjct: 61 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQI 112
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 56.6 bits (135), Expect = 3e-08 Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 4/115 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRH--- 277 +D ++ ++ IG G+FG +R +DT+++ A+K I + Y + ++ + R++ Sbjct: 344 IDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVD 403 Query: 278 -PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGV 439 P I+ K +P L V+ + GGELF + RF AR++ +L+C + Sbjct: 404 CPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCAL 458
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 56.6 bits (135), Expect = 3e-08 Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 3/117 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAM-KFIER--GYRIDENVFREIVNHRSLRH 277 M+KYE + +IG G++GV RN+DT ++VA+ KF+E I + REI + L+H Sbjct: 1 MEKYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQLKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 PN++ EV L +V EY L E E + Q + V+FC Sbjct: 61 PNLVNLMEVFRRKRKLHLVFEYCDHTVLNELDRYPRGVPEHMVKSIIWQTLQAVNFC 117
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 56.6 bits (135), Expect = 3e-08 Identities = 36/119 (30%), Positives = 63/119 (52%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 MD+YE V +IG G +GV R++ T E +A+K I + + REI + ++H Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE--ARYFFQQLVCGVSFC 448 NI+R ++VV + L +V EY +L + + F +D + F Q++ G+++C Sbjct: 61 GNIVRLQDVVHSEKRLYLVFEY-LDLDLKKHMDSCPDFAKDPRMIKRFLYQILRGIAYC 118
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 56.2 bits (134), Expect = 4e-08 Identities = 29/116 (25%), Positives = 62/116 (53%), Gaps = 4/116 (3%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLRH 277 D++E ++ +G+G++G L+R+R+T AMK +++ + +N + ++ Sbjct: 40 DQFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRILQAINF 99 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 P +++ + ++L +VMEY GGE+F + RF E +A ++ Q+V + Sbjct: 100 PFLVKLQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGRFSEPQACFYAAQVVLAFQY 155
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 56.2 bits (134), Expect = 4e-08 Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 4/138 (2%) Frame = +2 Query: 44 SREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY 223 S + + T N S ++ + ++ +E ++ +G G FG L R + T +L A+K +++ Sbjct: 243 SEQFSVQGTTCNSSGVKKVT-LENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEV 301 Query: 224 RIDENVFREIVNH----RSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRF 391 I ++ + +S HP +I K T L VM+Y GGELF + F Sbjct: 302 IIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIF 361 Query: 392 HEDEARYFFQQLVCGVSF 445 ED R++ +++ + + Sbjct: 362 TEDRTRFYGAEIISALGY 379
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 56.2 bits (134), Expect = 4e-08 Identities = 31/118 (26%), Positives = 56/118 (47%), Gaps = 4/118 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENVFREIVNHRSLR 274 +D +E R +G G FG L R + + +VA+K + + ++ + REI L Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 HPNI+R + +++EYA GEL++ + + F E ++L + +C Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYC 191
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 56.2 bits (134), Expect = 4e-08 Identities = 43/163 (26%), Positives = 66/163 (40%), Gaps = 39/163 (23%) Frame = +2 Query: 44 SREIATHRKTSNRSRERERSGMDK---------YEPVREIGSGNFGVAKLMRNRDTRELV 196 SRE A T+++SR GM K +E V +G+G+ G KL ++R T E+ Sbjct: 87 SRENAPKPNTTSQSRVSSSQGMPKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVC 146 Query: 197 AMKFIERGYRI------------------------------DENVFREIVNHRSLRHPNI 286 A+K + R + D+ RE + L HP+I Sbjct: 147 AVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHI 206 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYF 415 R E+ H ++ EY +GG+L + I E +AR F Sbjct: 207 CRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKF 249
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 56.2 bits (134), Expect = 4e-08 Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 3/117 (2%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMK-FIER--GYRIDENVFREIVNHRSLRH 277 M+KYE + +IG G++GV RNRDT ++VA+K F+E I + REI + L+H Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 PN++ EV L +V EY L E E + Q + V+FC Sbjct: 61 PNLVSLLEVFRRKRRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFC 117
>ST32A_HUMAN (Q8WU08) Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1)| Length = 396 Score = 56.2 bits (134), Expect = 4e-08 Identities = 31/123 (25%), Positives = 61/123 (49%), Gaps = 4/123 (3%) Frame = +2 Query: 89 ERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIV 256 E E D +E +R IG G+FG +++ DT+++ AMK++ + ++ NVF+E+ Sbjct: 14 ENEDVNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQ 73 Query: 257 NHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCG 436 + L HP ++ + +V++ GG+L + F E+ + F +LV Sbjct: 74 IMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEETVKLFICELVMA 133 Query: 437 VSF 445 + + Sbjct: 134 LDY 136
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 56.2 bits (134), Expect = 4e-08 Identities = 37/118 (31%), Positives = 58/118 (49%), Gaps = 12/118 (10%) Frame = +2 Query: 128 REIGSGNFGVAKL---------MRNRDTRELVAMKFIERGYRIDEN-VFREIVNHRSL-- 271 R IG+G FG KL +R T ++V + + + RE+ + L Sbjct: 496 RTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNCQTSRLMREVAILKGLGN 555 Query: 272 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 HP+I+++ + V T H GIV++Y GGELF+ I R + A F QL+ GV++ Sbjct: 556 NHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLISGVAY 613
>SPEG_BRARE (Q696W0) Striated muscle preferentially expressed protein kinase (EC| 2.7.11.1) Length = 2995 Score = 56.2 bits (134), Expect = 4e-08 Identities = 35/140 (25%), Positives = 64/140 (45%), Gaps = 2/140 (1%) Frame = +2 Query: 32 SAPASREIATHRKTSNRSRERERSGMDK--YEPVREIGSGNFGVAKLMRNRDTRELVAMK 205 S+P +S +S R G+ + Y + E G FGV + R T ++ K Sbjct: 2652 SSPTPETPTGQAVSSTKSETTLRQGVPQKPYSFLDEKARGRFGVIRDCRENATGKMFIAK 2711 Query: 206 FIERGYRIDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAX 385 I + + + +E +SLR I+ E +TP +L ++ EY +G E+ + + D Sbjct: 2712 IIPYDQQTKQTIIKEYEILKSLRCERIMALHEAYITPRYLVLITEYCSGKEILQNLIDRF 2771 Query: 386 RFHEDEARYFFQQLVCGVSF 445 + ED+ F Q++ G+ + Sbjct: 2772 CYSEDDVVGFIVQILQGLEY 2791
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 56.2 bits (134), Expect = 4e-08 Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 5/109 (4%) Frame = +2 Query: 128 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYR-----IDENVFREIVNHRSLRHPNIIR 292 R++G G+F + + T E VA+K I++ + +N+ RE + +RHPNI + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 293 FKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGV 439 +++ T +VME GG L +I + R E EAR + +QL+ V Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAV 174
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 56.2 bits (134), Expect = 4e-08 Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 5/109 (4%) Frame = +2 Query: 128 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYR-----IDENVFREIVNHRSLRHPNIIR 292 R++G G+F + + T E VA+K I++ + +N+ RE + +RHPNI + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 293 FKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGV 439 +++ T +VME GG L +I + R E EAR + +QL+ V Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAV 174
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 56.2 bits (134), Expect = 4e-08 Identities = 33/114 (28%), Positives = 60/114 (52%), Gaps = 4/114 (3%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY----RIDENVFREIVNHRSLRHPN 283 +E + +G G FG L + + T +VA+K + + +I++ V REI +LRH N Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 I+R + +++E+A GEL++ + A RF E+ A + Q+ +S+ Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSY 202
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 55.8 bits (133), Expect = 5e-08 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 4/143 (2%) Frame = +2 Query: 29 CSAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKF 208 CS + + + + +R M+ ++ ++ +G G FG L+R + + + AMK Sbjct: 119 CSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI 178 Query: 209 IERGYRI-DENVFREIVNHRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERIC 376 +++ I + V + R L RHP + K T L VMEY GGELF + Sbjct: 179 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS 238 Query: 377 DAXRFHEDEARYFFQQLVCGVSF 445 F ED R++ ++V + + Sbjct: 239 RERVFSEDRTRFYGAEIVSALDY 261
>KCC1_METAN (O14408) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| Length = 382 Score = 55.8 bits (133), Expect = 5e-08 Identities = 36/113 (31%), Positives = 63/113 (55%), Gaps = 2/113 (1%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI-ERGYRIDEN-VFREIVNHRSLRHPNI 286 KY+ R +G+G +GV + + VA+K I ++ + +E V+ E+ + L HP+I Sbjct: 22 KYKFGRTLGAGTYGVVREADGPSGK--VAIKIILKKNVKGNEKMVYAELDMLQRLTHPHI 79 Query: 287 IRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 ++F + + IV + A GGELF+RICD +F E +A +Q++ V + Sbjct: 80 VKFVDWFESRDKFYIVTQLATGGELFDRICDQGKFTEVDASQTIRQIMTAVDY 132
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 55.8 bits (133), Expect = 5e-08 Identities = 40/120 (33%), Positives = 60/120 (50%), Gaps = 6/120 (5%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIE---RGYRIDENVFREIVNHRSLRH 277 MD ++ V +IG G +GV RN+ T +LVA+K I + REI + L+H Sbjct: 1 MDVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE---DEARYFFQQLVCGVSFC 448 PNII+ +VV L +V E+ + +R D+ E + + QL+ GVSFC Sbjct: 61 PNIIKLLDVVHREKKLYMVFEFLT--QDLKRHMDSSPTSELPLPVVKSYLAQLLEGVSFC 118
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 55.8 bits (133), Expect = 5e-08 Identities = 35/120 (29%), Positives = 59/120 (49%), Gaps = 6/120 (5%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYR---IDENVFREIVNHRSLRH 277 M+ ++ V +IG G +GV RNR+T E+VA+K I + REI + L H Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE---ARYFFQQLVCGVSFC 448 PNI++ +V+ T L +V E+ + ++ D + + QL+ G++FC Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFL--NQDLKKFMDGSNISGISLALVKSYLFQLLQGLAFC 118
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 55.8 bits (133), Expect = 5e-08 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 4/143 (2%) Frame = +2 Query: 29 CSAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKF 208 CS + + + + +R M+ ++ ++ +G G FG L+R + + + AMK Sbjct: 119 CSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI 178 Query: 209 IERGYRI-DENVFREIVNHRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERIC 376 +++ I + V + R L RHP + K T L VMEY GGELF + Sbjct: 179 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS 238 Query: 377 DAXRFHEDEARYFFQQLVCGVSF 445 F ED R++ ++V + + Sbjct: 239 RERVFSEDRTRFYGAEIVSALDY 261
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 55.8 bits (133), Expect = 5e-08 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 4/143 (2%) Frame = +2 Query: 29 CSAPASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKF 208 CS + + + + +R M+ ++ ++ +G G FG L+R + + + AMK Sbjct: 119 CSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI 178 Query: 209 IERGYRI-DENVFREIVNHRSL---RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERIC 376 +++ I + V + R L RHP + K T L VMEY GGELF + Sbjct: 179 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS 238 Query: 377 DAXRFHEDEARYFFQQLVCGVSF 445 F ED R++ ++V + + Sbjct: 239 RERVFSEDRTRFYGAEIVSALDY 261
>KPC1_CANAL (P43057) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1097 Score = 55.5 bits (132), Expect = 6e-08 Identities = 30/133 (22%), Positives = 65/133 (48%), Gaps = 7/133 (5%) Frame = +2 Query: 68 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFR 247 K+ R + + G+D ++ + +G GNFG L +R T +L A+K +++ + ++ + Sbjct: 754 KSGKSKRRKRKVGLDDFQFLAVLGKGNFGKVMLAESRHTSKLCAIKVLKKDFIVENDEAE 813 Query: 248 EIVNHRSL-------RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEA 406 + + + + HP ++ T + VMEY +GG+L I RF A Sbjct: 814 SVKSEKRVFLTANKEMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHI-QKNRFTAKRA 872 Query: 407 RYFFQQLVCGVSF 445 +++ +++ G+ + Sbjct: 873 KFYACEVLLGLKY 885
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 55.5 bits (132), Expect = 6e-08 Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 6/135 (4%) Frame = +2 Query: 59 THRKTSNRSRERE-RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-D 232 T +S+RSR R + + ++ +G G+FG L + T E+ A+K +++ I D Sbjct: 383 TRSPSSDRSRSHHSRISLHDFNFIKVLGKGSFGKVMLAEKKGTDEVYAIKVLKKDVIIQD 442 Query: 233 ENVFREIVNHR----SLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHED 400 ++V + R S +HP + T L VMEY GG+L +I A +F E Sbjct: 443 DDVECTMTEKRILALSAKHPFLTALHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEP 502 Query: 401 EARYFFQQLVCGVSF 445 AR++ ++ + F Sbjct: 503 RARFYAAEVTLALMF 517
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 55.5 bits (132), Expect = 6e-08 Identities = 30/116 (25%), Positives = 59/116 (50%), Gaps = 10/116 (8%) Frame = +2 Query: 128 REIGSGNFGVAKLMRNRDTRELVAMKFIERG----------YRIDENVFREIVNHRSLRH 277 R++GSG +G+ +L+ + T + AMK +++ + + V E ++L H Sbjct: 178 RKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSH 237 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 P ++R ++V P + +V+E+ GG+L RI ED ++ +F Q+ V + Sbjct: 238 PCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKY 293
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 55.5 bits (132), Expect = 6e-08 Identities = 37/133 (27%), Positives = 65/133 (48%), Gaps = 8/133 (6%) Frame = +2 Query: 71 TSNRSRERERSG---MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRI-DEN 238 TS+RS + G + + ++ +G G+FG L + T E+ A+K +++ + D++ Sbjct: 360 TSSRSASKVPGGTLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDD 419 Query: 239 VFREIVNHRSL----RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEA 406 V + R L +HP + T L VMEY GG+L +I A +F E A Sbjct: 420 VECTMCEKRILSLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRA 479 Query: 407 RYFFQQLVCGVSF 445 R++ ++ C + F Sbjct: 480 RFYAAEVTCALQF 492
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 55.5 bits (132), Expect = 6e-08 Identities = 29/117 (24%), Positives = 59/117 (50%), Gaps = 4/117 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSL----R 274 +D Y+ ++ +G+G FG L R+R + + AMK + I + N R++ R Sbjct: 271 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIR 330 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 HP +I + ++L ++ +Y GGELF + +A +F + ++ ++V + + Sbjct: 331 HPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEY 387
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 55.1 bits (131), Expect = 8e-08 Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 M KYE + +IG G +G +NR+T E+VA+K + + + + REI + L+H Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE--ARYFFQQLVCGVSFC 448 NI+R +V+ + L +V E+ + ++ D+ D + F QL+ G+ FC Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFC--DQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFC 117
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 55.1 bits (131), Expect = 8e-08 Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 M KYE + +IG G +G +NR+T E+VA+K + + + + REI + L+H Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE--ARYFFQQLVCGVSFC 448 NI+R +V+ + L +V E+ + ++ D+ D + F QL+ G+ FC Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFC--DQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFC 117
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 55.1 bits (131), Expect = 8e-08 Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 M KYE + +IG G +G +NR+T E+VA+K + + + + REI + L+H Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDE--ARYFFQQLVCGVSFC 448 NI+R +V+ + L +V E+ + ++ D+ D + F QL+ G+ FC Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFC--DQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFC 117
>ST32B_HUMAN (Q9NY57) Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2)| Length = 414 Score = 55.1 bits (131), Expect = 8e-08 Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 4/123 (3%) Frame = +2 Query: 89 ERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIV 256 E E D ++ +R IG G+FG +++ RDT+++ AMK++ + I+ NVFRE+ Sbjct: 14 ENEEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQ 73 Query: 257 NHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCG 436 + L HP ++ + +V++ GG+L + F E + + +L Sbjct: 74 IMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALA 133 Query: 437 VSF 445 + + Sbjct: 134 LEY 136
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 55.1 bits (131), Expect = 8e-08 Identities = 27/112 (24%), Positives = 61/112 (54%), Gaps = 4/112 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHR----SLR 274 +D ++ ++ +G+G+FG L++++++ AMK +++ + +N + ++ Sbjct: 40 LDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 99 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 P +++ + ++L +VMEY GGE+F + RF E AR++ Q+V Sbjct: 100 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 151
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 55.1 bits (131), Expect = 8e-08 Identities = 31/116 (26%), Positives = 65/116 (56%), Gaps = 4/116 (3%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY---RID-ENVFREIVNHRSLRH 277 ++Y+ ++ +G G+FG L +++ T A+K I + + + D +++ RE+ + L H Sbjct: 67 EQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH 126 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 NI++ E + +V + +GGELF+ I RF+E +A +Q++ G+++ Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITY 182
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 55.1 bits (131), Expect = 8e-08 Identities = 31/116 (26%), Positives = 65/116 (56%), Gaps = 4/116 (3%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY---RID-ENVFREIVNHRSLRH 277 ++Y+ ++ +G G+FG L +++ T A+K I + + + D +++ RE+ + L H Sbjct: 67 EQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH 126 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 NI++ E + +V + +GGELF+ I RF+E +A +Q++ G+++ Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITY 182
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 55.1 bits (131), Expect = 8e-08 Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 5/109 (4%) Frame = +2 Query: 128 REIGSGNFGVAKLMRNRDTRELVAMKFIERGYR-----IDENVFREIVNHRSLRHPNIIR 292 R++G G+F + + T E VA+K I++ + +N+ RE + +RHPNI + Sbjct: 66 RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQ 125 Query: 293 FKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGV 439 +++ T +VME GG L +I + R E EAR + +QL+ V Sbjct: 126 LLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAV 174
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 54.7 bits (130), Expect = 1e-07 Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 29/142 (20%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID------------------ 232 +++Y EIG G++GV KL N + AMK + + I Sbjct: 162 LNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGARPAPG 221 Query: 233 ---------ENVFREIVNHRSLRHPNIIRFKEVVLTPT--HLGIVMEYAAGGELFERICD 379 E V++EI + L HPN+++ EV+ P HL +V E G + E + Sbjct: 222 GCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPT 280 Query: 380 AXRFHEDEARYFFQQLVCGVSF 445 ED+AR++FQ L+ G+ + Sbjct: 281 LKPLSEDQARFYFQDLIKGIEY 302
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 54.7 bits (130), Expect = 1e-07 Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 29/142 (20%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID------------------ 232 +++Y EIG G++GV KL N + AMK + + I Sbjct: 162 LNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPG 221 Query: 233 ---------ENVFREIVNHRSLRHPNIIRFKEVVLTPT--HLGIVMEYAAGGELFERICD 379 E V++EI + L HPN+++ EV+ P HL +V E G + E + Sbjct: 222 GCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPT 280 Query: 380 AXRFHEDEARYFFQQLVCGVSF 445 ED+AR++FQ L+ G+ + Sbjct: 281 LKPLSEDQARFYFQDLIKGIEY 302
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 54.7 bits (130), Expect = 1e-07 Identities = 33/140 (23%), Positives = 72/140 (51%), Gaps = 4/140 (2%) Frame = +2 Query: 41 ASREIATHRKTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERG 220 + +E + +KT + S++R+ + ++ ++ R +G G FG L R + ++ ++A+K + + Sbjct: 103 SEKEQTSIQKTED-SKKRQWT-LEDFDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKV 160 Query: 221 YR----IDENVFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR 388 ++ + RE+ LRHPNI+R T + +++EYA G ++ + + Sbjct: 161 QLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK 220 Query: 389 FHEDEARYFFQQLVCGVSFC 448 F E + +L +S+C Sbjct: 221 FDEQRTATYITELANALSYC 240
>MYLK_HUMAN (Q15746) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin (Kinase-related protein) (KRP)] Length = 1914 Score = 54.7 bits (130), Expect = 1e-07 Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%) Frame = +2 Query: 95 ERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER-GYRIDENVFREIVNHRSL 271 E+ D Y+ +GSG FG + + TR++ A KF + + EN+ +EI L Sbjct: 1457 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCL 1516 Query: 272 RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDA-XRFHEDEARYFFQQLVCGVSF 445 HP +++ + ++ +V+E +GGELFERI D E E + +Q+ GV + Sbjct: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEY 1575
>ST32B_MOUSE (Q9JJX8) Serine/threonine-protein kinase 32B (EC 2.7.11.1)| Length = 414 Score = 54.7 bits (130), Expect = 1e-07 Identities = 30/123 (24%), Positives = 60/123 (48%), Gaps = 4/123 (3%) Frame = +2 Query: 89 ERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID----ENVFREIV 256 E E D ++ +R IG G+FG +++ RDT+++ AMK++ + ++ NVFRE+ Sbjct: 14 ENEEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCVERDEVRNVFRELQ 73 Query: 257 NHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCG 436 + L HP ++ + +V++ GG+L + F E + + +L Sbjct: 74 IMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALA 133 Query: 437 VSF 445 + + Sbjct: 134 LEY 136
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 54.7 bits (130), Expect = 1e-07 Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 29/142 (20%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRID------------------ 232 +++Y EIG G++GV KL N + AMK + + I Sbjct: 161 LNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPG 220 Query: 233 ---------ENVFREIVNHRSLRHPNIIRFKEVVLTPT--HLGIVMEYAAGGELFERICD 379 E V++EI + L HPN+++ EV+ P HL +V E G + E + Sbjct: 221 GCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPT 279 Query: 380 AXRFHEDEARYFFQQLVCGVSF 445 ED+AR++FQ L+ G+ + Sbjct: 280 LKPLSEDQARFYFQDLIKGIEY 301
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 54.7 bits (130), Expect = 1e-07 Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 4/120 (3%) Frame = +2 Query: 98 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSL-- 271 R + +++ +R +G+G FG L++N AMK + + Y + + + +S+ Sbjct: 330 RERLKEFKQIRVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILS 389 Query: 272 --RHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 HP I+ + L ++ EY AGGE+F + + +F A+++ ++V + F Sbjct: 390 SIHHPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEF 449
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 54.7 bits (130), Expect = 1e-07 Identities = 34/119 (28%), Positives = 63/119 (52%), Gaps = 5/119 (4%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 MD+YE V +IG G +GV R++ T E +A+K I + + REI + ++H Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHED--EARYFFQQLVCGVSFC 448 NI++ ++VV + L +V EY +L + + F +D + + Q++ G+++C Sbjct: 61 SNIVKLQDVVHSEKRLYLVFEY-LDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYC 118
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 54.3 bits (129), Expect = 1e-07 Identities = 29/115 (25%), Positives = 60/115 (52%), Gaps = 4/115 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSLRH--- 277 +D ++ ++ IG G+FG +R +DT+++ A+K + + Y + + + R++ Sbjct: 341 IDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVD 400 Query: 278 -PNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGV 439 P I+ K +P L +V+ + GGELF + RF +R++ +L+C + Sbjct: 401 CPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCAL 455
>NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) Length = 698 Score = 54.3 bits (129), Expect = 1e-07 Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 6/114 (5%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN---VFREIVNHRSLRH 277 M+KYE +R +G G FG+ L + ++LV +K I E E + L H Sbjct: 1 MEKYERIRVVGRGAFGIVHLCLRKADQKLVILKQIPVEQMTKEERQAAQNECQVLKLLNH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERI---CDAXRFHEDEARYFFQQLV 430 PN+I + E L L I MEYA GG L E I C++ E+ +FF Q++ Sbjct: 61 PNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSL-LEEETILHFFVQIL 113
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 54.3 bits (129), Expect = 1e-07 Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%) Frame = +2 Query: 116 YEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDENVFREIVNHRSL----RHPN 283 +E +R +G G+ G LMR RDT ++ A+K + + I + ++ + + HP Sbjct: 324 FEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPF 383 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERI--CDAXRFHEDEARYFFQQLVCGVSF 445 I+ T +L + MEY GGE F + + E++A+++ ++V + + Sbjct: 384 IVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEY 439
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 54.3 bits (129), Expect = 1e-07 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 8/119 (6%) Frame = +2 Query: 98 RSGMDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY--------RIDENVFREI 253 +S YE +R +GSG F V KL ++ + A+K I + R E REI Sbjct: 161 KSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREI 220 Query: 254 VNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLV 430 +SL HP +++ E+ L IVMEY GG+L + + E + + +QL+ Sbjct: 221 DILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLL 279
>NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a) Length = 692 Score = 53.9 bits (128), Expect = 2e-07 Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 6/114 (5%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN---VFREIVNHRSLRH 277 M+KYE +R +G G FG+ L + ++LV +K I E E + L H Sbjct: 1 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEYAAGGELFERI---CDAXRFHEDEARYFFQQLV 430 PN+I + E L L I MEYA GG L E I C++ E+ +FF Q++ Sbjct: 61 PNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSL-LEEETILHFFVQIL 113
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 53.9 bits (128), Expect = 2e-07 Identities = 43/145 (29%), Positives = 65/145 (44%), Gaps = 6/145 (4%) Frame = +2 Query: 32 SAPASREIATHRKTSNRSRERERSGM-DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKF 208 + P+ + HR SN + + KY +E+G G FG + +L A K Sbjct: 52 TGPSLKPRQVHRPESNTILGKPFEDIRGKYTLGKELGRGQFGCVYQCTENSSGQLYACKS 111 Query: 209 IERGYRIDENVFREIVNH-RSLRH----PNIIRFKEVVLTPTHLGIVMEYAAGGELFERI 373 I + + +N +I + L+H PNI+ FK V + +VME AGGELF+RI Sbjct: 112 ILKRKLVSKNDKEDIKREIQILQHLSGQPNIVEFKGVFEDRQSVHLVMELCAGGELFDRI 171 Query: 374 CDAXRFHEDEARYFFQQLVCGVSFC 448 + E A +Q+V V C Sbjct: 172 IAQGHYSERAAATICRQIVNVVHVC 196
>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3 (EC| 2.7.11.24) (P43) Length = 372 Score = 53.9 bits (128), Expect = 2e-07 Identities = 40/120 (33%), Positives = 61/120 (50%), Gaps = 9/120 (7%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY--RIDE-NVFREIVNHRSLRHPN 283 KY P++ IG G +G+ NR+T E VA+K I + RID RE+ R LRH N Sbjct: 31 KYVPIKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTLRELKLLRHLRHEN 90 Query: 284 IIRFKEVVLTPTH------LGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 +I K+V++ P H + +V E +L + I + D +YF QL+ G+ + Sbjct: 91 VIALKDVMM-PIHRRSFKDVYLVYE-LMDTDLHQIIKSSQTLSNDHCQYFLFQLLRGLKY 148
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 53.9 bits (128), Expect = 2e-07 Identities = 37/118 (31%), Positives = 57/118 (48%), Gaps = 7/118 (5%) Frame = +2 Query: 113 KYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGY--RIDE-NVFREIVNHRSLRHPN 283 KY P++ IG G +GV NR+T E VA+K I + R+D RE+ R +RH N Sbjct: 31 KYVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLRHVRHEN 90 Query: 284 IIRFKEVVLTPTHLGIVMEYAA----GGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 +I K+V+L Y +L + I + +D +YF QL+ G+ + Sbjct: 91 VIALKDVMLPANRSSFKDVYLVYELMDTDLHQIIKSSQSLSDDHCKYFLFQLLRGLKY 148
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 53.9 bits (128), Expect = 2e-07 Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 4/117 (3%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIERGYRIDEN-VFREIVNHRSLR--- 274 MD ++ ++ +G G FG L R + + +L A+K I + +D + V + +R L Sbjct: 177 MDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACV 236 Query: 275 HPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSF 445 HP + K H+ VME+A GGELF + F E R++ +++ + + Sbjct: 237 HPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGY 293
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 53.9 bits (128), Expect = 2e-07 Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 3/109 (2%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI--ERGYRIDENVFREIVNHRSLRHPN 283 D Y+ +G+G F L ++ T++LVA+K I E + ++ EI ++HPN Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPN 77 Query: 284 IIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHE-DEARYFFQQL 427 I+ ++ + HL ++M+ +GGELF+RI + + E D +R FQ L Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVL 126
>KCC1_EMENI (Q00771) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CMPK) Length = 414 Score = 53.9 bits (128), Expect = 2e-07 Identities = 39/129 (30%), Positives = 69/129 (53%), Gaps = 3/129 (2%) Frame = +2 Query: 68 KTSNRSRERERSGMDKYEPVREIGSGNFGVAKLMRNRDTRE-LVAMKFI-ERGYRIDEN- 238 K S + E+ + ++ R +G+G +G+ +R D VA+K I +R R +E Sbjct: 9 KLSGQPESYEKKSLYRFG--RTLGAGTYGI---VREADCSSGKVAVKIILKRNVRGNERM 63 Query: 239 VFREIVNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFF 418 V+ E+ + L HP+I+ F + + IV + A GGELF+RIC+ +F E +A Sbjct: 64 VYDELDLLQKLNHPHIVHFVDWFESKDKFYIVTQLATGGELFDRICEYGKFTEKDASQTI 123 Query: 419 QQLVCGVSF 445 +Q++ V++ Sbjct: 124 RQVLDAVNY 132
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 53.9 bits (128), Expect = 2e-07 Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 4/108 (3%) Frame = +2 Query: 134 IGSGNFGVAKLMRNRDTRELVAMKFI-ERGYRIDENVFREIVNHRSLRHPNIIRFKEVVL 310 +G G +GV R+R TR +A+K I ER R + + EI HR LRH NI+R+ Sbjct: 377 LGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSAS 436 Query: 311 TPTHLGIVMEYAAGG---ELFERICDAXRFHEDEARYFFQQLVCGVSF 445 +L I ME GG L + + +E ++ +Q++ G+ + Sbjct: 437 QGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGY 484
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 53.5 bits (127), Expect = 2e-07 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 3/116 (2%) Frame = +2 Query: 110 DKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFIER---GYRIDENVFREIVNHRSLRHP 280 D+Y+ E+G G F V + T + A K I R + + RE R L+HP Sbjct: 12 DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71 Query: 281 NIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXRFHEDEARYFFQQLVCGVSFC 448 NI+R + + +V + GGELFE I + E +A + QQ++ V+ C Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHC 127
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 53.5 bits (127), Expect = 2e-07 Identities = 36/127 (28%), Positives = 60/127 (47%), Gaps = 13/127 (10%) Frame = +2 Query: 107 MDKYEPVREIGSGNFGVAKLMRNRDTRELVAMKFI---ERGYRIDENVFREIVNHRSLRH 277 M KYE + +IG G +G +NR+T E+VA+K + + + + REI + L+H Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60 Query: 278 PNIIRFKEVVLTPTHLGIVMEY----------AAGGELFERICDAXRFHEDEARYFFQQL 427 NI+R +V+ + L +V E+ + G+L I + F QL Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSLLF----------QL 110 Query: 428 VCGVSFC 448 + G+ FC Sbjct: 111 LKGLGFC 117
>ST17A_HUMAN (Q9UEE5) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) Length = 414 Score = 53.5 bits (127), Expect = 2e-07 Identities = 43/134 (32%), Positives = 67/134 (50%), Gaps = 9/134 (6%) Frame = +2 Query: 71 TSNRSRERERSGMDKYE--PVREIGSGNFGVAKLMRNRDTRELVAMKFIER---GYRIDE 235 T R+ R D Y P RE+G G F V + +D+ + A KF+ + G Sbjct: 44 TEIRAVVRTEPFQDGYSLCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRM 103 Query: 236 NVFREI-VNHRSLRHPNIIRFKEVVLTPTHLGIVMEYAAGGELFERICDAXR---FHEDE 403 + EI V + +P +I EV T + + +V+EYAAGGE+F++ C A R F E + Sbjct: 104 EIIHEIAVLELAQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQ-CVADREEAFKEKD 162 Query: 404 ARYFFQQLVCGVSF 445 + +Q++ GV F Sbjct: 163 VQRLMRQILEGVHF 176 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 52,931,108 Number of Sequences: 219361 Number of extensions: 1129899 Number of successful extensions: 7399 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6437 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6817 length of database: 80,573,946 effective HSP length: 102 effective length of database: 58,199,124 effective search space used: 2735358828 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
