>AVT1_YEAST (P47082) Vacuolar amino acid transporter 1|
          Length = 602

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 19/45 (42%), Positives = 27/45 (60%)
 Frame = +1

Query: 250 ITAVIGSGVLSLAWGVAQLGWVAGPVCMLCFAVVTYVSASLLSDC 384
           I  +IG G+L+L  G+   GWV G   +  FA+ T+ +A LLS C
Sbjct: 218 INVLIGIGLLALPLGLKYAGWVIGLTMLAIFALATFCTAELLSRC 262

>PACC_ASPFU (Q4WY67) pH-response transcription factor pacC/RIM101|
          Length = 676

 Score = 32.3 bits (72), Expect = 0.46
 Identities = 16/55 (29%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
 Frame = -3

Query: 320 PATHPSCATPQ--ASDSTPDPITAVMMCAAHVHSVPVRGGLPSSSHRPSITWREC 162
           P++ P+  TP   ++ + P  +TA    A    S P   G P S  + S  W+ C
Sbjct: 33  PSSQPAATTPAPVSTSTPPASVTATAAAATAAVSAPQANGTPPSDEQLSCLWQGC 87

>S36A1_HUMAN (Q7Z2H8) Proton-coupled amino acid transporter 1 (Proton/amino acid|
           transporter 1) (Solute carrier family 36 member 1)
          Length = 476

 Score = 32.3 bits (72), Expect = 0.46
 Identities = 15/47 (31%), Positives = 23/47 (48%)
 Frame = +1

Query: 244 HIITAVIGSGVLSLAWGVAQLGWVAGPVCMLCFAVVTYVSASLLSDC 384
           H++   IG+G+L L   V   G V GP+ +L   +V      +L  C
Sbjct: 55  HLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKC 101

>MSHR_CALGO (Q864H6) Melanocyte-stimulating hormone receptor (MSH-R)|
           (Melanotropin receptor) (Melanocortin receptor 1)
           (MC1-R)
          Length = 344

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 11/21 (52%), Positives = 11/21 (52%), Gaps = 3/21 (14%)
 Frame = +2

Query: 275 CCRWPGAWRSWDG---WPGRC 328
           C RWPG W    G   WPG C
Sbjct: 315 CSRWPGCWAEGGGDSVWPGSC 335

>S36A1_RAT (Q924A5) Proton-coupled amino acid transporter 1 (Proton/amino acid|
           transporter 1) (Solute carrier family 36 member 1)
           (Lysosomal amino acid transporter 1) (LYAAT-1) (Neutral
           amino acid/proton symporter)
          Length = 475

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 14/47 (29%), Positives = 23/47 (48%)
 Frame = +1

Query: 244 HIITAVIGSGVLSLAWGVAQLGWVAGPVCMLCFAVVTYVSASLLSDC 384
           H++   IG+G+L L   V   G + GP+ +L   +V      +L  C
Sbjct: 54  HLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKC 100

>S36A1_MOUSE (Q8K4D3) Proton-coupled amino acid transporter 1 (Proton/amino acid|
           transporter 1) (Solute carrier family 36 member 1)
          Length = 475

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 14/47 (29%), Positives = 23/47 (48%)
 Frame = +1

Query: 244 HIITAVIGSGVLSLAWGVAQLGWVAGPVCMLCFAVVTYVSASLLSDC 384
           H++   IG+G+L L   V   G + GP+ +L   +V      +L  C
Sbjct: 54  HLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVKC 100

>LSHB_EQUBU (O46641) Lutropin/choriogonadotropin beta chain precursor|
           (LSH-B/CG-B) (Lutenizing hormone beta subunit)
          Length = 169

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 17/45 (37%), Positives = 20/45 (44%)
 Frame = -3

Query: 323 GPATHPSCATPQASDSTPDPITAVMMCAAHVHSVPVRGGLPSSSH 189
           GP  HP    PQAS S+ DP +  +       S P  G    SSH
Sbjct: 122 GPRDHPLACAPQASSSSKDPPSQPLTST----STPTPGASNRSSH 162

>ANGL2_MOUSE (Q9R045) Angiopoietin-related protein 2 precursor|
           (Angiopoietin-like 2)
          Length = 493

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 13/34 (38%), Positives = 19/34 (55%)
 Frame = -3

Query: 227 SVPVRGGLPSSSHRPSITWRECCTAIAPAPRRSS 126
           ++P    LPSS+ +PS  WR+C  A+      SS
Sbjct: 257 TMPALTSLPSSTDKPSGPWRDCLQALEDGHSTSS 290

>PYRB_METAC (Q8THL2) Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartate|
           transcarbamylase) (ATCase)
          Length = 308

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 20/58 (34%), Positives = 25/58 (43%)
 Frame = -3

Query: 266 PITAVMMCAAHVHSVPVRGGLPSSSHRPSITWRECCTAIAPAPRRSSHWAKIRAAFTG 93
           P+      AA   SVPV  G   S H P+ T+ +  T      RR SH   +R A  G
Sbjct: 109 PLDGSARMAAEFASVPVINGGDGSVHHPTQTFLDLYTI-----RRESHLEDLRIAMAG 161

>AVT7_YEAST (P40501) Vacuolar amino acid transporter 7|
          Length = 490

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 13/56 (23%), Positives = 29/56 (51%)
 Frame = +1

Query: 217 TGTEWTCAAHIITAVIGSGVLSLAWGVAQLGWVAGPVCMLCFAVVTYVSASLLSDC 384
           T +  +  A+++  ++G+G L++ +     G + G +  L  AV + +   +LS C
Sbjct: 4   TSSALSSTANLVKTIVGAGTLAIPYSFKSDGVLVGVILTLLAAVTSGLGLFVLSKC 59

>ANGL2_HUMAN (Q9UKU9) Angiopoietin-related protein 2 precursor|
           (Angiopoietin-like 2)
          Length = 493

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 13/34 (38%), Positives = 19/34 (55%)
 Frame = -3

Query: 227 SVPVRGGLPSSSHRPSITWRECCTAIAPAPRRSS 126
           ++P    LPSS+ +PS  WR+C  A+      SS
Sbjct: 257 TMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSS 290

>MSHR_CALJA (Q864H7) Melanocyte-stimulating hormone receptor (MSH-R)|
           (Melanotropin receptor) (Melanocortin receptor 1)
           (MC1-R)
          Length = 344

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 10/21 (47%), Positives = 10/21 (47%), Gaps = 3/21 (14%)
 Frame = +2

Query: 275 CCRWPGAWRSWDG---WPGRC 328
           C  WPG W    G   WPG C
Sbjct: 315 CSSWPGCWAEGGGDSVWPGSC 335

>MSHR_CALGE (Q864H8) Melanocyte-stimulating hormone receptor (MSH-R)|
           (Melanotropin receptor) (Melanocortin receptor 1)
           (MC1-R)
          Length = 344

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 10/21 (47%), Positives = 10/21 (47%), Gaps = 3/21 (14%)
 Frame = +2

Query: 275 CCRWPGAWRSWDG---WPGRC 328
           C  WPG W    G   WPG C
Sbjct: 315 CSSWPGCWAEGGGDSVWPGSC 335

>MURB_ANASP (Q8YM74) UDP-N-acetylenolpyruvoylglucosamine reductase (EC|
           1.1.1.158) (UDP-N-acetylmuramate dehydrogenase)
          Length = 331

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 10/21 (47%), Positives = 14/21 (66%)
 Frame = +1

Query: 250 ITAVIGSGVLSLAWGVAQLGW 312
           +T   G  + SLAW +A+LGW
Sbjct: 123 VTIAAGESIPSLAWEIAKLGW 143

>P73_HUMAN (O15350) Tumor protein p73 (p53-like transcription factor)|
           (p53-related protein)
          Length = 636

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 19/59 (32%), Positives = 22/59 (37%)
 Frame = -3

Query: 320 PATHPSCATPQASDSTPDPITAVMMCAAHVHSVPVRGGLPSSSHRPSITWRECCTAIAP 144
           P  H S ATP      P       M   H H+VP  G + SS    S+     CT   P
Sbjct: 434 PPPHSSAATPNLGPVGPG------MLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPP 486

>MAML1_HUMAN (Q92585) Mastermind-like protein 1 (Mam-1)|
          Length = 1016

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 21/70 (30%), Positives = 31/70 (44%)
 Frame = -3

Query: 347  TAKQSMHTGPATHPSCATPQASDSTPDPITAVMMCAAHVHSVPVRGGLPSSSHRPSITWR 168
            TA  S H     H   ++PQ S + P+   A M  AA V S+            P ++ +
Sbjct: 861  TAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSL-----------LPPVSAQ 909

Query: 167  ECCTAIAPAP 138
            +  +A APAP
Sbjct: 910  QRTSAPAPAP 919

>TOP1_AERPE (Q9YB01) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)|
           (Omega-protein) (Relaxing enzyme) (Untwisting enzyme)
           (Swivelase)
          Length = 673

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
 Frame = -3

Query: 263 ITAVMMCAAHVHSVP-VRGGLPSSSHRPSITWRECCTAIAPAPRRSSHWAKIRAAFTGRD 87
           ++   +C+ H+ +   +R  LP+ +   S T RE   AIA    R+  W +  AA   RD
Sbjct: 606 VSGYRLCSHHMEAFDRLRKALPNLASTISSTPREALEAIARGRSRAGAWVRDVAALALRD 665

>LSHB_EQUAS (P19794) Lutropin/choriogonadotropin beta chain precursor|
           (LSH-B/CG-B) (Lutenizing hormone beta subunit)
          Length = 169

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 16/45 (35%), Positives = 18/45 (40%)
 Frame = -3

Query: 323 GPATHPSCATPQASDSTPDPITAVMMCAAHVHSVPVRGGLPSSSH 189
           GP  HP    PQ S S  DP +  +       S P  G    SSH
Sbjct: 122 GPRDHPLACAPQTSSSCKDPPSQPLTST----STPTPGASRRSSH 162

>KR101_HUMAN (P60331) Keratin-associated protein 10-1 (Keratin-associated|
           protein 10.1) (High sulfur keratin-associated protein
           10.1) (Keratin-associated protein 18-1)
           (Keratin-associated protein 18.1)
          Length = 282

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 17/62 (27%), Positives = 24/62 (38%), Gaps = 1/62 (1%)
 Frame = -3

Query: 311 HPSCATPQ-ASDSTPDPITAVMMCAAHVHSVPVRGGLPSSSHRPSITWRECCTAIAPAPR 135
           HP+C T      +   P+    +C   +  VPV  G  +S  + S     CCT     P 
Sbjct: 170 HPACCTSSPCQQACCVPVRCKPVCCKPICCVPVCSGASTSCCQQSSCQPACCTTSCCRPS 229

Query: 134 RS 129
            S
Sbjct: 230 SS 231

>ICP0_HHV2H (P28284) Trans-acting transcriptional protein ICP0 (VMW118 protein)|
          Length = 825

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 16/49 (32%), Positives = 23/49 (46%)
 Frame = -3

Query: 272 PDPITAVMMCAAHVHSVPVRGGLPSSSHRPSITWRECCTAIAPAPRRSS 126
           P P++ V   +A V S P  GGLP SS R +         +   PR ++
Sbjct: 379 PGPLSFVSSSSAQVSSGPGGGGLPQSSGRAARPRAAVAPRVRSPPRAAA 427

>Y1709_RALSO (Q8XYP9) UPF0209 protein RSc1709|
          Length = 657

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
 Frame = +1

Query: 262 IGSGVLSLAWGVAQLGWVAGP-VCMLCFA 345
           +G+GV    W  AQ GWVA P +C    A
Sbjct: 379 VGAGVPQGGWWFAQAGWVAPPDICRAALA 407


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,204,430
Number of Sequences: 219361
Number of extensions: 1059592
Number of successful extensions: 3666
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 3432
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3658
length of database: 80,573,946
effective HSP length: 101
effective length of database: 58,418,485
effective search space used: 2278320915
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)