ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bast65h03 |
|---|---|
| Clone Library Name | barley_pub |
>ALDR_MOUSE (P45376) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 135 bits (341), Expect = 2e-32 Identities = 64/112 (57%), Positives = 77/112 (68%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P++GLGTW+S PG V +AV A+ GYRHIDCAQVY NEKE+G AL++ E V R+D Sbjct: 12 MPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQD 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 LFI SKLWCT H V A TL DLQ DY+DLYL+HWP K G + P Sbjct: 72 LFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFP 123
>ALDR_RAT (P07943) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 135 bits (340), Expect = 3e-32 Identities = 64/112 (57%), Positives = 77/112 (68%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P++GLGTW+S PG V +AV A+ GYRHIDCAQVY NEKE+G AL++ E V R+D Sbjct: 12 MPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQD 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 LFI SKLWCT H V A TL DLQ DY+DLYL+HWP K G + P Sbjct: 72 LFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFP 123
>AK1A1_MOUSE (Q9JII6) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 132 bits (333), Expect = 2e-31 Identities = 64/108 (59%), Positives = 78/108 (72%), Gaps = 1/108 (0%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG-VTTRK 179 +P +GLGTW+SEPG V A+ A+ AGYRHIDCA VYGNE EIG ALK+ G R+ Sbjct: 13 MPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPRE 72 Query: 180 DLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 +LF+TSKLW T H PEDV AL TL DLQ +Y+DLYL+HWP ++G Sbjct: 73 ELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 120
>ALDR_BOVIN (P16116) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 315 Score = 130 bits (328), Expect = 6e-31 Identities = 62/112 (55%), Positives = 74/112 (66%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P +GLGTW+S PG V +AV A+ GYRHIDCA VY NE E+G AL+ E V R+D Sbjct: 12 MPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEQVVKRED 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 LFI SKLWCT H + V A TL DL+ DY+DLYL+HWP K G F P Sbjct: 72 LFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKDFFP 123
>AK1A1_HUMAN (P14550) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 130 bits (326), Expect = 1e-30 Identities = 63/108 (58%), Positives = 77/108 (71%), Gaps = 1/108 (0%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG-VTTRK 179 +P +GLGTW+SEPG V AV A+ GYRHIDCA +YGNE EIG ALK+ G R+ Sbjct: 13 MPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPRE 72 Query: 180 DLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 +LF+TSKLW T H PEDV AL TL DLQ +Y+DLYL+HWP ++G Sbjct: 73 ELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 120
>AK1A1_RAT (P51635) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (3-DG-reducing enzyme) Length = 324 Score = 129 bits (325), Expect = 1e-30 Identities = 62/108 (57%), Positives = 77/108 (71%), Gaps = 1/108 (0%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG-VTTRK 179 +P +GLGTW+SEPG V A+ A+ GYRHIDCA VYGNE EIG ALK+ G R+ Sbjct: 13 MPLIGLGTWKSEPGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKESVGAGKAVPRE 72 Query: 180 DLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 +LF+TSKLW T H PEDV A+ TL DLQ +Y+DLYL+HWP ++G Sbjct: 73 ELFVTSKLWNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAFERG 120
>ALDR_HORVU (P23901) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 320 Score = 129 bits (324), Expect = 2e-30 Identities = 61/113 (53%), Positives = 77/113 (68%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P+VGLGTW++ A +AGYRH+D A YG EKE+G LK + G+ RKD Sbjct: 24 MPAVGLGTWRAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAGID-RKD 82 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 LF+TSK+WCTN APE V AL+ TL+DLQ DY+DLY +HWP R+K GA PE Sbjct: 83 LFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAHMPPE 135
>ALDR_RABIT (P15122) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 129 bits (323), Expect = 2e-30 Identities = 60/112 (53%), Positives = 76/112 (67%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P +GLGTW+S PG V +AV A+ GYRHIDCA VY NE E+G AL++ E V R++ Sbjct: 12 MPILGLGTWKSPPGQVTEAVKTAIDLGYRHIDCAHVYQNENEVGVALQEKLKEQVVKREE 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 LFI SKLWCT+H V A TL DL+ DY+DLYL+HWP K G+ + P Sbjct: 72 LFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGSEYFP 123
>YDG7_SCHPO (Q10494) Probable oxidoreductase C26F1.07 in chromosome I (EC| 1.-.-.-) Length = 321 Score = 129 bits (323), Expect = 2e-30 Identities = 59/107 (55%), Positives = 76/107 (71%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP +GLGTW+SEP +AV A++ GYRHID A +YGNE E+G +K E RKD Sbjct: 24 IPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK----ESGVPRKD 79 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 +++TSKLWC HAPE VP AL+ TL+DL+ DY+D YL+HWP+ K G Sbjct: 80 IWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTG 126
>AK1E1_MOUSE (Q9DCT1) Aldo-keto reductase family 1 member E1 (EC 1.1.1.-)| Length = 301 Score = 128 bits (321), Expect = 4e-30 Identities = 57/107 (53%), Positives = 71/107 (66%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP+VGLGTW++ PG V DAV A+ GYRH DCA +Y NE E+G + + EGV R+D Sbjct: 4 IPTVGLGTWKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKRED 63 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 LF+ SKLWCT H V A TL+ L DY+DLYL+HWP+ K G Sbjct: 64 LFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFKPG 110
>AK1A1_PIG (P50578) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 127 bits (320), Expect = 5e-30 Identities = 61/108 (56%), Positives = 76/108 (70%), Gaps = 1/108 (0%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG-VTTRK 179 +P +GLGTW+SEPG V A+ A+ GYRHIDCA +YGNE EIG AL + G R+ Sbjct: 13 MPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIYGNELEIGEALTETVGPGKAVPRE 72 Query: 180 DLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 +LF+TSKLW T H PEDV AL TL DLQ +Y+DLYL+HWP ++G Sbjct: 73 ELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 120
>ALDR_HUMAN (P15121) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 127 bits (318), Expect = 9e-30 Identities = 60/112 (53%), Positives = 74/112 (66%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P +GLGTW+S PG V +AV A+ GYRHIDCA VY NE E+G A+++ E V R++ Sbjct: 12 MPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREE 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 LFI SKLWCT H V A TL DL+ DY+DLYL+HWP K G F P Sbjct: 72 LFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 123
>AK1A1_CRIGR (O70473) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (Fragment) Length = 228 Score = 125 bits (315), Expect = 2e-29 Identities = 61/105 (58%), Positives = 74/105 (70%), Gaps = 1/105 (0%) Frame = +3 Query: 12 VGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG-VTTRKDLF 188 +GLGTW+S PG V A+ A+ GYRHIDCA VYGNE EIG ALK+ G R++LF Sbjct: 2 IGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELF 61 Query: 189 ITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 +TSKLW T H PEDV AL TL DLQ +Y+DLYL+HWP ++G Sbjct: 62 VTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFERG 106
>ALDR_PIG (P80276) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 125 bits (314), Expect = 3e-29 Identities = 58/107 (54%), Positives = 72/107 (67%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P +GLGTW+S PG V +AV A+ GYRHIDCA VY NE E+G L++ V R+D Sbjct: 12 MPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKLQGQVVKRED 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 LFI SKLWCT+H V A TL+DL+ DY+DLYL+HWP K G Sbjct: 72 LFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPG 118
>ALD1_MOUSE (P21300) Aldose reductase-related protein 1 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (VAS deferens androgen-dependent protein) (MVDP) (Aldo-keto reductase family 1 member B7) Length = 315 Score = 123 bits (308), Expect = 1e-28 Identities = 60/113 (53%), Positives = 73/113 (64%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P VGLGTW+S PG V +AV AA+ AGYRHIDCA VY NE E+G A+++ E R+D Sbjct: 12 MPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAVKRED 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 LFI SKLW T V A TL DL+ DY+DLYLVHWP + G P+ Sbjct: 72 LFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNALLPK 124
>XYL1_CANSH (Q9P430) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 323 Score = 122 bits (306), Expect = 2e-28 Identities = 53/105 (50%), Positives = 76/105 (72%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +PS+G G W+ + D VY A+KAGYR D A+ YGNE+E+G +K+ DEG+ TR++ Sbjct: 17 MPSIGFGCWKLDKSTAADQVYNAIKAGYRLFDGAEDYGNEQEVGEGVKRAIDEGIVTREE 76 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 +F+TSKLW H P++V AL+ TL+DL+ DYVDL+L+H+PI K Sbjct: 77 IFLTSKLWNNYHDPKNVETALNKTLKDLKVDYVDLFLIHFPIAFK 121
>XYL1_CANTE (O74237) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 322 Score = 119 bits (299), Expect = 1e-27 Identities = 53/105 (50%), Positives = 74/105 (70%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +PS+G G W+ G+ VY A+KAGYR D A+ YGNEKE+G +K+ DEG+ R++ Sbjct: 16 MPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGDGVKRAIDEGLVKREE 75 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 +F+TSKLW H P++V AL+ TL DL+ DYVDL+L+H+PI K Sbjct: 76 IFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFK 120
>ALDX_SPOSA (P27800) Aldehyde reductase 1 (EC 1.1.1.2) (Aldehyde reductase I)| (Alcohol dehydrogenase [NADP+]) (ALR) Length = 322 Score = 117 bits (294), Expect = 5e-27 Identities = 54/99 (54%), Positives = 70/99 (70%) Frame = +3 Query: 12 VGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKDLFI 191 VG GTWQ+ PG VG V A++ GYRH+D A+VY N+ E+G A+K E R+DLFI Sbjct: 15 VGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK----EAGVKREDLFI 70 Query: 192 TSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPI 308 TSKLW +H PE V ALD TL++L +Y+DLYL+HWP+ Sbjct: 71 TSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPV 109
>ALD2_CRIGR (O08782) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Aldo-keto reductase) Length = 315 Score = 116 bits (290), Expect = 2e-26 Identities = 57/113 (50%), Positives = 73/113 (64%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P VGLGTWQS PG V +AV A+ AGYRHIDCA Y NE E+G A+++ E R+D Sbjct: 12 MPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEKIKEKAVRRED 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 LFI SKLW T + + A TL DL+ DY+DLYL+HWP ++ G P+ Sbjct: 72 LFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPK 124
>XYL1_PICGU (O94735) NADPH-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 317 Score = 115 bits (289), Expect = 2e-26 Identities = 51/105 (48%), Positives = 71/105 (67%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +PSVG G W+ + D +Y A+K GYR D A+ YGNEKE+G + + DEG+ R + Sbjct: 11 MPSVGFGCWKVDNATCADTIYNAIKVGYRLFDGAEDYGNEKEVGDGINRALDEGLVARDE 70 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 LF+ SKLW + H P++V ALD TL DL+ DY+DL+L+H+PI K Sbjct: 71 LFVVSKLWNSFHDPKNVEKALDKTLSDLKVDYLDLFLIHFPIAFK 115
>XYL1_PICST (P31867) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 115 bits (288), Expect = 3e-26 Identities = 51/105 (48%), Positives = 71/105 (67%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P+VG G W+ + + +Y A+K GYR D A+ Y NEK +G +KK DEG+ R+D Sbjct: 12 MPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAIDEGIVKRED 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 LF+TSKLW H P++V AL+ TL DLQ DYVDL+L+H+P+ K Sbjct: 72 LFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFK 116
>ALD2_MOUSE (P45377) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Fibroblast growth factor-regulated protein) (FR-1 protein) Length = 315 Score = 114 bits (286), Expect = 5e-26 Identities = 56/113 (49%), Positives = 73/113 (64%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P VGLGTW+S P V +AV AA+ AGYRHIDCA Y NE E+G A+++ E R+D Sbjct: 12 MPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVQRED 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 LFI SKLW T + + A TL DL+ DY+DLYL+HWP ++ G P+ Sbjct: 72 LFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPK 124
>XYL1_PACTA (P78736) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 112 bits (280), Expect = 2e-25 Identities = 55/105 (52%), Positives = 69/105 (65%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP++G+G W+ E D VYAA+K GYR DCA YGNEKE+G + + +G+ RKD Sbjct: 14 IPAIGMGCWKLENAA--DMVYAAIKEGYRLFDCACDYGNEKEVGEGINRAIKDGLVKRKD 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 LFITSKLW HA E+V AL +L D DY DLYL+H+PI K Sbjct: 72 LFITSKLWNNFHAKENVKKALMKSLSDFNLDYFDLYLMHFPISFK 116
>AK1BA_HUMAN (O60218) Aldo-keto reductase family 1 member B10 (EC 1.1.1.-)| (Aldose reductase-like) (ARL-1) (Small intestine reductase) (SI reductase) (Aldose reductase-related protein) (ARP) (hARP) Length = 316 Score = 112 bits (280), Expect = 2e-25 Identities = 56/113 (49%), Positives = 72/113 (63%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P VGLGTW+S G V +AV A+ AGYRHIDCA VY NE E+G A+++ E R+D Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 LFI SKLW T V A + TL+DL+ Y+D+YL+HWP K G P+ Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPK 125
>DHB5_MOUSE (P70694) Estradiol 17 beta-dehydrogenase 5 (EC 1.1.1.-)| (17-beta-HSD 5) Length = 323 Score = 112 bits (279), Expect = 3e-25 Identities = 53/116 (45%), Positives = 75/116 (64%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEP---GVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP +G GT+ + +A A+ AG+RHID A +Y NEKE+G A++ +G Sbjct: 16 IPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+D+F TSK+WCT H PE V V L+ +L+ LQ DYVDLYL+H+P+ MK G + P+ Sbjct: 76 REDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKPGENYLPK 131
>XYL1_CANTR (O13283) NAD(P)H-dependent D-xylose reductase I,II (EC 1.1.1.-)| (XR) Length = 324 Score = 111 bits (277), Expect = 5e-25 Identities = 51/105 (48%), Positives = 68/105 (64%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P VG G W+ D +Y A+K GYR D A+ YGNEKE+G + + EG+ R++ Sbjct: 18 MPLVGFGCWKVTNATAADQIYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEGLVKREE 77 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 LFITSKLW H P++V AL+ TL DL DYVDL+L+H+PI K Sbjct: 78 LFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFK 122
>XYL2_CANTR (P87039) NADPH-dependent D-xylose reductase II,III (EC 1.1.1.-)| (XR) Length = 324 Score = 110 bits (276), Expect = 7e-25 Identities = 51/105 (48%), Positives = 68/105 (64%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P VG G W+ D +Y A+K GYR D A+ YGNEKE+G + + EG+ R++ Sbjct: 18 MPLVGFGCWKVNNETAADQIYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEGLVKREE 77 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 LFITSKLW H P++V AL+ TL DL DYVDL+L+H+PI K Sbjct: 78 LFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFK 122
>XYL1_KLULA (P49378) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 329 Score = 110 bits (275), Expect = 9e-25 Identities = 50/105 (47%), Positives = 69/105 (65%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P VGLG W+ V D +Y A+K GYR D AQ Y NEKE+G + + EG+ R+D Sbjct: 16 MPLVGLGCWKMPNDVCADQIYEAIKIGYRLFDGAQDYANEKEVGQGVNRAIKEGLVKRED 75 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 L + SKLW + H P++VP AL+ TL DLQ DYVD++ +H+P+ K Sbjct: 76 LVVVSKLWNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFK 120
>GRE3_YEAST (P38715) NADPH-dependent aldose reductase GRE3 (EC 1.1.1.21)| (NADPH-dependent aldo-keto reductase GRE3) (NADPH-dependent methylglyoxal reductase GRE3) (EC 1.1.1.-) (Xylose reductase) (EC 1.1.1.-) (Genes de respuesta a estres protein 3) Length = 327 Score = 110 bits (274), Expect = 1e-24 Identities = 50/105 (47%), Positives = 69/105 (65%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P VGLG W+ + V + +Y A+K GYR D A YGNEKE+G ++K EG+ +RKD Sbjct: 13 MPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVSRKD 72 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 +F+ SKLW H P+ V +AL TL D+ DY+DLY +H+PI K Sbjct: 73 IFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFK 117
>GCY_YEAST (P14065) GCY protein (EC 1.1.1.-)| Length = 312 Score = 109 bits (272), Expect = 2e-24 Identities = 55/104 (52%), Positives = 72/104 (69%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP +GLGTWQS+ AV A+K GYRHID A +Y NE ++G A+K D GV R++ Sbjct: 20 IPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK---DSGV-PREE 75 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRM 314 +F+T+KLWCT H + VALD +L+ L DYVDLYL+HWP R+ Sbjct: 76 IFVTTKLWCTQH--HEPEVALDQSLKRLGLDYVDLYLMHWPARL 117
>XYL1_CANPA (Q6Y0Z3) NADH-dependent D-xylose reductase (EC 1.1.1.175) (XR)| Length = 324 Score = 108 bits (270), Expect = 3e-24 Identities = 51/105 (48%), Positives = 69/105 (65%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP VG G W+ V D +Y A+K+GYR D A+ Y NE+E+G +K+ EG+ R++ Sbjct: 18 IPLVGFGCWKLTNDVASDQIYRAIKSGYRLFDGAEDYANEQEVGEGIKRAIKEGIVKREE 77 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 LFITSKLW + H ++V VAL TL DL DYVDL+ +H+PI K Sbjct: 78 LFITSKLWNSFHDKKNVEVALMKTLSDLNLDYVDLFYIHFPIAQK 122
>PE2R_RABIT (P80508) Prostaglandin-E(2) 9-reductase (EC 1.1.1.189)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 107 bits (267), Expect = 7e-24 Identities = 53/115 (46%), Positives = 73/115 (63%), Gaps = 3/115 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP +G GT+ E A+ A A+ AG+RHID A Y NEKE+G A++ +G Sbjct: 16 IPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRSKIADGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 R+D+F TSKLWCT H PE V +L+ +L++LQ DYVDLY++H+P +K G P Sbjct: 76 REDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGVEIIP 130
>AK1C1_MACFU (Q95JH6) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 106 bits (264), Expect = 2e-23 Identities = 50/116 (43%), Positives = 75/116 (64%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 +P +G GT+ A+ A A++AG+RHID A +Y NE+ +G A++ +G Sbjct: 16 MPVLGFGTYAPAEVPKNKAIEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKIADGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+D+F TSKLWC +H PE V AL+ +L++LQ DYVDLYL+H+P+ +K G P+ Sbjct: 76 REDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLKPGEELIPK 131
>AK1C1_PONPY (Q5REQ0) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 105 bits (262), Expect = 3e-23 Identities = 51/116 (43%), Positives = 76/116 (65%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 +P +G GT+ A+ A A++AG+RHID A +Y NE+++G A++ +G Sbjct: 16 MPVLGFGTYAPPEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+D+F TSKLWC +H PE V AL+ +L++LQ DYVDLYLVH+P+ +K G P+ Sbjct: 76 REDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLVHFPVSVKPGEEVIPK 131
>AK1C1_MACFA (Q95JH7) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 105 bits (262), Expect = 3e-23 Identities = 50/116 (43%), Positives = 75/116 (64%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 +P +G GT+ A+ A A++AG+RHID A +Y NE+ +G A++ +G Sbjct: 16 MPVLGFGTYAPAEVPKNKALEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKIADGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+D+F TSKLWC +H PE V AL+ +L++LQ DYVDLYL+H+P+ +K G P+ Sbjct: 76 REDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLKPGEELIPK 131
>AK1C1_HUMAN (Q04828) Aldo-keto reductase family 1 member C1 (EC 1.1.1.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (High-affinity hepatic bile acid-binding protei Length = 323 Score = 105 bits (261), Expect = 4e-23 Identities = 50/116 (43%), Positives = 76/116 (65%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 +P +G GT+ A+ A A++AG+RHID A +Y NE+++G A++ +G Sbjct: 16 MPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+D+F TSKLWC +H PE V AL+ +L++LQ DYVDLYL+H+P+ +K G P+ Sbjct: 76 REDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPK 131
>AKC1H_RAT (P51652) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (HSD1) Length = 323 Score = 104 bits (260), Expect = 5e-23 Identities = 49/116 (42%), Positives = 76/116 (65%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP +G GT+ +E + ++ + A+ G+RHIDC+ +Y NE+EIG A+ ++G Sbjct: 16 IPVLGFGTYATEENLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKIEDGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+D+F TSKLW T+H PE V +L+ +L+ L DYVDLYL+H+P+ +K G P+ Sbjct: 76 REDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGDELLPQ 131
>PGFS2_BOVIN (P52897) Prostaglandin-F synthase 2 (EC 1.1.1.188) (PGF synthase 2)| (PGF 2) (Prostaglandin-D2 11 reductase 2) (PGFSII) Length = 323 Score = 104 bits (259), Expect = 6e-23 Identities = 50/116 (43%), Positives = 76/116 (65%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP +G GT+ E +A+ A A++ G+RH+D A +Y NE+++G A++ +G Sbjct: 16 IPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKIADGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+D+F TSKLWC + PE V AL+ +LQ+LQ DYVDLY++H P+ +K G F P+ Sbjct: 76 REDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLKPGNKFVPK 131
>PGFS1_BOVIN (P05980) Prostaglandin-F synthase 1 (EC 1.1.1.188) (PGF synthase 1)| (PGF 1) (Prostaglandin-D2 11 reductase 1) (PGFSI) Length = 323 Score = 104 bits (259), Expect = 6e-23 Identities = 50/116 (43%), Positives = 76/116 (65%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP +G GT+ E +A+ A A++ G+RH+D A +Y NE+++G A++ +G Sbjct: 16 IPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKIADGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+D+F TSKLWC + PE V AL+ +LQ+LQ DYVDLY++H P+ +K G F P+ Sbjct: 76 REDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLKPGNKFVPK 131
>CRO_RANTE (P02532) Rho crystallin| Length = 323 Score = 104 bits (259), Expect = 6e-23 Identities = 48/115 (41%), Positives = 71/115 (61%), Gaps = 3/115 (2%) Frame = +3 Query: 3 IPSVGLGTWQSE---PGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 +P +GLGT+ S + +AV A+ GYRHIDCA + GNE IG ++ +G Sbjct: 16 MPILGLGTYASPHVPKSLAEEAVKIAIDVGYRHIDCAFITGNEMHIGNGIRSKISDGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 R+D+F T KLWCT +PE V L+ +L+D+ DY+DL+L+HWP+ +K +P Sbjct: 76 REDIFYTGKLWCTYFSPEMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASDP 130
>AK1D1_RAT (P31210) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 103 bits (256), Expect = 1e-22 Identities = 53/116 (45%), Positives = 71/116 (61%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTWQSE---PGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP +GLGT+ PG AV A+ GYRHID A VY NE E+G A+++ EG Sbjct: 18 IPIIGLGTYSDPRPVPGKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIREKVAEGKVK 77 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+++F KLW T+H PE V AL+ TLQ L+ DY+DLY++ P+ K G F P+ Sbjct: 78 REEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFKPGEEFYPK 133
>CRO_RANCA (P17264) Rho crystallin| Length = 323 Score = 102 bits (254), Expect = 2e-22 Identities = 46/115 (40%), Positives = 71/115 (61%), Gaps = 3/115 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEP---GVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 +P +GLGT+ + + +AV A+ GYRHIDCA + GNE IG ++ +G Sbjct: 16 MPILGLGTYAAPDVPKSLAEEAVKTAIDVGYRHIDCAFITGNEMHIGNGIRSKISDGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 R+D+F T KLWCT +P+ V L+ +L+D+ DY+DL+L+HWP+ +K +P Sbjct: 76 REDIFYTGKLWCTYFSPDMVRKGLERSLRDVGMDYLDLFLMHWPVSLKPSGASDP 130
>AK1D1_HUMAN (P51857) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 102 bits (253), Expect = 3e-22 Identities = 54/117 (46%), Positives = 70/117 (59%), Gaps = 5/117 (4%) Frame = +3 Query: 3 IPSVGLGTWQSEP-----GVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 IP +GLGT+ SEP G +V A+ GYRHID A +Y NE E+G A+++ EG Sbjct: 18 IPIIGLGTY-SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGK 76 Query: 168 TTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 R+D+F KLW TNH PE V L+ TL+ LQ DYVDLY++ P+ K G P Sbjct: 77 VRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYP 133
>AK1C2_HUMAN (P52895) Aldo-keto reductase family 1 member C2 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) ( Length = 323 Score = 102 bits (253), Expect = 3e-22 Identities = 49/116 (42%), Positives = 75/116 (64%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTW---QSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 +P +G GT+ + +AV A++AG+ HID A VY NE+++G A++ +G Sbjct: 16 MPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+D+F TSKLW +H PE V AL+ +L++LQ DYVDLYL+H+P+ +K G P+ Sbjct: 76 REDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPK 131
>AKC1H_MOUSE (Q8K023) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 100 bits (250), Expect = 7e-22 Identities = 48/116 (41%), Positives = 75/116 (64%), Gaps = 3/116 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP +G GT+ +E + ++ + A+ G+ HIDC+ +Y NE+EIG A+ ++G Sbjct: 16 IPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKIEDGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNPE 341 R+D+F TSKLW T+H PE V +L+ +L+ L DYVDLYL+H+P+ +K G P+ Sbjct: 76 REDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELLPK 131
>AK1CD_MOUSE (Q8VC28) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| Length = 323 Score = 100 bits (250), Expect = 7e-22 Identities = 52/110 (47%), Positives = 72/110 (65%), Gaps = 3/110 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKA---GYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP++G GT++ + ++ AA A GYRH+D A Y E+EIG A++ GV Sbjct: 16 IPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 R+DLFIT+KLWCT PE V AL+ +L+ LQ DYVDLY++H+P+ MK G Sbjct: 76 REDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSG 125
>AK1C4_MACFA (Q95JH5) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 100 bits (249), Expect = 9e-22 Identities = 49/111 (44%), Positives = 74/111 (66%), Gaps = 4/111 (3%) Frame = +3 Query: 3 IPSVGLGTWQSEPGV----VGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVT 170 +P +G GT+ + P V V + A++AG+RHID A +Y NE+++G A++ +G Sbjct: 16 MPVLGFGTY-APPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSV 74 Query: 171 TRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 R+D+F TSKLWCT P+ V AL+ +L+ LQ DYVDLYL+H+P+ +K G Sbjct: 75 KREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPG 125
>AK1C4_MACFU (Q95JH4) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 99.0 bits (245), Expect = 3e-21 Identities = 48/111 (43%), Positives = 74/111 (66%), Gaps = 4/111 (3%) Frame = +3 Query: 3 IPSVGLGTWQSEPGV----VGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVT 170 +P +G G++ + P V V + A++AG+RHID A +Y NE+++G A++ +G Sbjct: 16 MPVLGFGSY-APPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSV 74 Query: 171 TRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 R+D+F TSKLWCT P+ V AL+ +L+ LQ DYVDLYL+H+P+ +K G Sbjct: 75 KREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPG 125
>AK1C4_HUMAN (P17516) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (HAKRA) Length = 323 Score = 98.6 bits (244), Expect = 3e-21 Identities = 48/110 (43%), Positives = 71/110 (64%), Gaps = 3/110 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 +P +G GT+ AV A++AG+RHID A +Y NE+++G A++ +G Sbjct: 16 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 R+D+F TSKLWCT P+ V AL+ +L+ LQ DYVDLYL+H+P+ +K G Sbjct: 76 REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 125
>YPR1_YEAST (Q12458) Putative reductase 1 (EC 1.1.1.-)| Length = 312 Score = 98.2 bits (243), Expect = 4e-21 Identities = 53/105 (50%), Positives = 71/105 (67%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP +G GTW+S +V AA+KAGYRHID A +Y NE+E+G A+K D GV R++ Sbjct: 20 IPVLGFGTWRSVDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIK---DSGV-PREE 75 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 +FIT+KLW T D AL+ +L+ L DYVDLYL+HWP+ +K Sbjct: 76 IFITTKLWGTEQ--RDPEAALNKSLKRLGLDYVDLYLMHWPVPLK 118
>DDBX_BOVIN (P52898) Dihydrodiol dehydrogenase 3 (EC 1.-.-.-) (Prostaglandin F| synthase) Length = 323 Score = 97.8 bits (242), Expect = 6e-21 Identities = 48/115 (41%), Positives = 73/115 (63%), Gaps = 3/115 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP +G GT+ +A+ A++AG+RHID A +Y NE+++G A++ +G Sbjct: 16 IPVLGFGTFAPREVPKSEALEVTKFAIEAGFRHIDSAHLYQNEEQVGQAIRSKIADGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 R+D+F TSKLW T+ PE V AL+ +L +LQ DYVDLY++H+P+ +K G P Sbjct: 76 REDIFYTSKLWSTSLRPELVRPALEKSLNNLQLDYVDLYIIHFPVALKPGETLFP 130
>AK1C3_PONPY (Q5R7C9) Aldo-keto reductase family 1 member C3 homolog (EC| 1.-.-.-) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (Prostaglandin F synthase) Length = 323 Score = 97.8 bits (242), Expect = 6e-21 Identities = 49/116 (42%), Positives = 73/116 (62%), Gaps = 4/116 (3%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVG----DAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVT 170 +P +G GT+ + P V + A++AG+RHID A +Y NE+++G A++ +G Sbjct: 16 MPVLGFGTY-APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSV 74 Query: 171 TRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 R+D+F TSKLW T H PE V AL+ +L+ Q DYVDLYL+H P+ +K G +P Sbjct: 75 KREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSP 130
>AK1C3_HUMAN (P42330) Aldo-keto reductase family 1 member C3 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (3-alpha-HSD type II, brain) (Prost Length = 323 Score = 97.8 bits (242), Expect = 6e-21 Identities = 49/116 (42%), Positives = 73/116 (62%), Gaps = 4/116 (3%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVG----DAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVT 170 +P +G GT+ + P V + A++AG+RHID A +Y NE+++G A++ +G Sbjct: 16 MPVLGFGTY-APPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSV 74 Query: 171 TRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 R+D+F TSKLW T H PE V AL+ +L+ Q DYVDLYL+H P+ +K G +P Sbjct: 75 KREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSP 130
>S6PD_MALDO (P28475) NADP-dependent D-sorbitol-6-phosphate dehydrogenase (EC| 1.1.1.200) (Aldose-6-phosphate reductase [NADPH]) (NADP-S6PDH) Length = 310 Score = 97.4 bits (241), Expect = 8e-21 Identities = 46/108 (42%), Positives = 69/108 (63%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P +GLG W+ E + + + A+K GYRH DCA Y +E ++G AL + F G+ R++ Sbjct: 12 MPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFKTGLVKREE 71 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 326 LFIT+K+W ++H V A +L+ LQ DY+DLYLVH+P+ K A Sbjct: 72 LFITTKIWNSDHG--HVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNA 117
>AK1D1_MOUSE (Q8VCX1) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 325 Score = 96.3 bits (238), Expect = 2e-20 Identities = 52/116 (44%), Positives = 69/116 (59%), Gaps = 4/116 (3%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKA----GYRHIDCAQVYGNEKEIGFALKKVFDEGVT 170 IP +GLGT+ S+P V Y AVK GYRHID A VY NE E+G A+++ EG Sbjct: 18 IPLIGLGTY-SDPRPVPGKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREKIAEGKV 76 Query: 171 TRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 R+++F KLW T H P V AL+ TL+ L+ DY+DLY++ P+ K G P Sbjct: 77 KREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFKPGKEIYP 132
>XYL1_TRIRE (Q876L8) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 324 Score = 96.3 bits (238), Expect = 2e-20 Identities = 48/105 (45%), Positives = 62/105 (59%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P VG G W+ + V D VY A+KAGYR D A YGNEKE G + + +G+ R+D Sbjct: 14 MPQVGFGLWKVDNAVCADTVYNAIKAGYRLFDGACDYGNEKECGEGVARAIKDGLVKRED 73 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 LFI SKLW T H + V L D Q DY DL+LVH+P ++ Sbjct: 74 LFIVSKLWQTFHDEDKVEPITRRQLADWQIDYFDLFLVHFPAALE 118
>6DCS_SOYBN (P26690) NAD(P)H dependent 6'-deoxychalcone synthase (EC 2.3.1.170)| Length = 315 Score = 95.9 bits (237), Expect = 2e-20 Identities = 44/90 (48%), Positives = 62/90 (68%) Frame = +3 Query: 54 DAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPEDV 233 +A+ AVK GYRH D A YG+E+ +G ALK+ G+ +R+DLF+TSKLW T + P V Sbjct: 40 EAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLV 99 Query: 234 PVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 AL +L+ LQ +Y+DLYL+HWP+ + G Sbjct: 100 LPALRKSLKTLQLEYLDLYLIHWPLSSQPG 129
>DIDH_RAT (P23457) 3-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.213)| (3-alpha-HSD) (Hydroxyprostaglandin dehydrogenase) Length = 322 Score = 94.0 bits (232), Expect = 8e-20 Identities = 47/115 (40%), Positives = 69/115 (60%), Gaps = 3/115 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYA---AVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP +G GT E + + A A+ G+RH D A +Y E+E+G A++ ++G Sbjct: 16 IPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRSKIEDGTVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGAGFNP 338 R+D+F TSKLW T H PE V L+ TL+ Q DYVDLY++H+P+ ++ G F P Sbjct: 76 REDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQPGDIFFP 130
>AK1D1_RABIT (Q9TV64) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 92.8 bits (229), Expect = 2e-19 Identities = 49/112 (43%), Positives = 66/112 (58%), Gaps = 5/112 (4%) Frame = +3 Query: 3 IPSVGLGTWQSEP-----GVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 IP +GLGT+ SEP G +V A+ GYRHID A +Y NE E+G ++ EG Sbjct: 18 IPIIGLGTY-SEPKTTPKGSCATSVKIAIDTGYRHIDGAYIYQNEHEVGETFREKIAEGK 76 Query: 168 TTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 R+D+F KLW TNH P V L+ TL+ L+ DY+DLY++ P+ K G Sbjct: 77 VRREDIFYCGKLWATNHDPVMVRPTLERTLKVLKLDYIDLYIIEIPMAFKPG 128
>DTDH_MUCMU (Q01213) 4-dihydromethyl-trisporate dehydrogenase (EC 1.1.1.-)| (4-dihydromethyl-TA dehydrogenase) Length = 321 Score = 91.7 bits (226), Expect = 4e-19 Identities = 43/105 (40%), Positives = 63/105 (60%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P G G W+ + + VY A+K GYR D A YGNE E+G + K +EG+ R+D Sbjct: 15 MPIRGFGCWKIDTKDCEETVYQAIKTGYRLFDGACDYGNEVEVGRGINKAINEGLVKRED 74 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 LFI +KLW T H+ + V D L+D +Y DLYL+H+P+ ++ Sbjct: 75 LFIVTKLWNTFHSKKHVRALFDRQLKDTGLEYFDLYLIHFPVPLQ 119
>P100_LEIMA (P22045) Probable reductase (EC 1.1.-.-)| Length = 284 Score = 91.3 bits (225), Expect = 5e-19 Identities = 49/102 (48%), Positives = 63/102 (61%), Gaps = 1/102 (0%) Frame = +3 Query: 3 IPSVGLGTWQSEPG-VVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRK 179 +P GLG WQS G V +AV A+ AGYRHID A +Y NE+ +G L+ GV R+ Sbjct: 17 MPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGLRA---SGVP-RE 72 Query: 180 DLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 D+FIT+KLW T E A + + Q L DY+DLYL+HWP Sbjct: 73 DVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP 114
>AK1CD_MESAU (P82809) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| (Morphine 6-dehydrogenase) (EC 1.1.1.218) Length = 322 Score = 89.7 bits (221), Expect = 2e-18 Identities = 45/110 (40%), Positives = 67/110 (60%), Gaps = 3/110 (2%) Frame = +3 Query: 3 IPSVGLGTWQS---EPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT 173 IP++G GT++ +A A+ GYRHID A Y E+EIG A++ G+ Sbjct: 16 IPALGFGTYKPIEVPKSKAMEAANLAIGVGYRHIDTAYAYQIEEEIGQAIQSNIKAGIVK 75 Query: 174 RKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 R+D+FIT+KLWCT PE V +L+ LQ ++VDL+++H+P+ MK G Sbjct: 76 REDMFITTKLWCTCFQPELVRPSLEKXXXKLQLEHVDLFIMHYPVPMKAG 125
>DKGA_YERPE (Q8ZI40) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 87.0 bits (214), Expect = 1e-17 Identities = 48/102 (47%), Positives = 63/102 (61%), Gaps = 1/102 (0%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P +GLG WQ+ AV A++ GYR ID A +Y NE+ +G ALK R + Sbjct: 15 MPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKALK----AAAVARDE 70 Query: 183 LFITSKLWCTN-HAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 LFIT+KLW + H P+ AL+ +LQ LQ DYVDLYL+HWP Sbjct: 71 LFITTKLWNDDQHNPQQ---ALETSLQKLQLDYVDLYLIHWP 109
>DKGB_ECO57 (Q8X7Z7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 86.7 bits (213), Expect = 1e-17 Identities = 44/101 (43%), Positives = 65/101 (64%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP+ GLGT++ + VV +V A++ GYR ID AQ+Y NE +G A+ E R + Sbjct: 3 IPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAAVGLAIA----ESGVPRHE 58 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 L+IT+K+W N + + + +L +LQ L+TDYVDL L+HWP Sbjct: 59 LYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWP 99
>DKGB_YERPE (Q8ZH36) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 85.9 bits (211), Expect = 2e-17 Identities = 44/101 (43%), Positives = 65/101 (64%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP GLGT++ + +V D+V A+ GYR ID AQ+Y NE +G A++ E R + Sbjct: 3 IPVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAIQ----ESGINRDE 58 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 LFIT+K+W N + + + +L ++Q L+TDYVDL L+HWP Sbjct: 59 LFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP 99
>DKGB_ECOLI (P30863) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 85.9 bits (211), Expect = 2e-17 Identities = 44/101 (43%), Positives = 65/101 (64%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP+ GLGT++ + VV +V A++ GYR ID AQ+Y NE +G A+ E R + Sbjct: 3 IPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAAVGQAIA----ESGVPRHE 58 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 L+IT+K+W N + + + +L +LQ L+TDYVDL L+HWP Sbjct: 59 LYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWP 99
>DKGA_ECOLI (Q46857) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 85.5 bits (210), Expect = 3e-17 Identities = 46/103 (44%), Positives = 64/103 (62%), Gaps = 1/103 (0%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P +GLG WQ+ V A+ A++ GYR ID A Y NE+ +G ALK R++ Sbjct: 15 MPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALK----NASVNREE 70 Query: 183 LFITSKLWCTNH-APEDVPVALDGTLQDLQTDYVDLYLVHWPI 308 LFIT+KLW +H P + AL +L+ LQ DY+DLYL+HWP+ Sbjct: 71 LFITTKLWNDDHKRPRE---ALLDSLKKLQLDYIDLYLMHWPV 110
>XYL1_ASPNG (Q9P8R5) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 319 Score = 85.5 bits (210), Expect = 3e-17 Identities = 43/105 (40%), Positives = 58/105 (55%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P VG G W+ D +Y A+K GYR D A YGNE E G + + +G+ R++ Sbjct: 14 MPLVGFGLWKVNNDTCADQIYHAIKEGYRLFDGACDYGNEVEAGQGIARAIKDGLVKREE 73 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMK 317 LFI SKLW + H + V L D DY DLY+VH+PI +K Sbjct: 74 LFIVSKLWNSFHDGDRVEPICRKQLADWGIDYFDLYIVHFPISLK 118
>DKGA_CORSC (P06632) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 85.1 bits (209), Expect = 4e-17 Identities = 45/101 (44%), Positives = 60/101 (59%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP +G G ++ P AV A++ GYRHID A +YGNE+ +G A+ G+ R D Sbjct: 13 IPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIAA---SGIA-RDD 68 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 LFIT+KLW H ++ A+ +L L D VDLYLVHWP Sbjct: 69 LFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP 109
>DKGA_ECO57 (Q8XBT6) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 84.0 bits (206), Expect = 9e-17 Identities = 45/103 (43%), Positives = 63/103 (61%), Gaps = 1/103 (0%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P +GLG WQ+ V A+ A++ GYR D A Y NE+ +G ALK R++ Sbjct: 15 MPQLGLGVWQASNEEVITAIQKALEVGYRSFDTAAAYKNEEGVGKALK----NASVNREE 70 Query: 183 LFITSKLWCTNH-APEDVPVALDGTLQDLQTDYVDLYLVHWPI 308 LFIT+KLW +H P + AL +L+ LQ DY+DLYL+HWP+ Sbjct: 71 LFITTKLWNDDHNRPRE---ALLDSLKKLQLDYIDLYLMHWPV 110
>DKGB_SALTY (Q8ZRM7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 83.2 bits (204), Expect = 1e-16 Identities = 42/101 (41%), Positives = 65/101 (64%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP+ GLGT++ + VV +V A++ GYR +D AQ+Y NE +G A+ E R + Sbjct: 3 IPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIA----ESGVPRNE 58 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 L+IT+K+W N + + + +L +L+ L+TDYVDL L+HWP Sbjct: 59 LYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWP 99
>DKGB_SALTI (Q8Z988) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 83.2 bits (204), Expect = 1e-16 Identities = 42/101 (41%), Positives = 65/101 (64%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 IP+ GLGT++ + VV +V A++ GYR +D AQ+Y NE +G A+ E R + Sbjct: 3 IPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIA----ESGVPRNE 58 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 L+IT+K+W N + + + +L +L+ L+TDYVDL L+HWP Sbjct: 59 LYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWP 99
>ARA1_YEAST (P38115) D-arabinose dehydrogenase [NAD(P)+] heavy chain (EC| 1.1.1.117) Length = 344 Score = 82.8 bits (203), Expect = 2e-16 Identities = 46/108 (42%), Positives = 68/108 (62%), Gaps = 2/108 (1%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVG--DAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTR 176 IP++GLGT + AV AA+KAGYRHID A Y E +G A+K++ ++G R Sbjct: 33 IPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKR 92 Query: 177 KDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKK 320 +DLFIT+K+W ++V +L+ +L+ L +YVDL L HWP+ +K Sbjct: 93 EDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEK 138
>DKGA_SALTY (Q8ZM06) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 82.8 bits (203), Expect = 2e-16 Identities = 44/102 (43%), Positives = 63/102 (61%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P +GLG W++ V A++ A++ GYR ID A Y NE+ +G ALK R++ Sbjct: 15 MPQLGLGVWKASNEEVIAAIHKALEVGYRSIDTATAYQNEEGVGKALK----AASVAREE 70 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPI 308 LFIT+KLW N + AL +L+ LQ DY+DLYL+HWP+ Sbjct: 71 LFITTKLW--NDDQKRPREALQESLKKLQLDYLDLYLMHWPV 110
>DKGA_SALTI (P58744) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 82.8 bits (203), Expect = 2e-16 Identities = 44/102 (43%), Positives = 63/102 (61%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P +GLG W++ V A++ A++ GYR ID A Y NE+ +G ALK R++ Sbjct: 15 MPQLGLGVWKASNEEVIAAIHKALEVGYRSIDTATAYQNEEGVGKALK----AASVAREE 70 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPI 308 LFIT+KLW N + AL +L+ LQ DY+DLYL+HWP+ Sbjct: 71 LFITTKLW--NDDQKRPREALQESLKKLQLDYLDLYLMHWPV 110
>NADO1_ORYSA (Q7G764) Probable NAD(P)H-dependent oxidoreductase 1 (EC 1.1.1.-)| Length = 321 Score = 82.4 bits (202), Expect = 3e-16 Identities = 47/114 (41%), Positives = 69/114 (60%), Gaps = 7/114 (6%) Frame = +3 Query: 3 IPSVGLGT-----WQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG- 164 +P VG+GT SE A+ A++ GYRH D A++Y E +G A+ + G Sbjct: 16 MPRVGMGTAAFPFTSSEDTTA--AMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGL 73 Query: 165 VTTRKDLFITSKLWCTN-HAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 + +R D+F+TSK+WC++ HA VP A + TL++L DYVDL LVHWP+ + G Sbjct: 74 IASRADVFVTSKIWCSDLHAGRVVPAARE-TLRNLGMDYVDLLLVHWPVSLTPG 126
>AFR_PIG (P82125) 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) (AF| reductase) (Fragments) Length = 206 Score = 81.3 bits (199), Expect = 6e-16 Identities = 44/108 (40%), Positives = 58/108 (53%), Gaps = 1/108 (0%) Frame = +3 Query: 3 IPSVGLGTWQSEPG-VVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRK 179 IP +GLGTWQ+ PG V +AV A+ GYRH D A +Y NE E+G ++ DEGV R+ Sbjct: 2 IPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRRE 61 Query: 180 DLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKG 323 DLFI SK + Y+DL +HWP++ K G Sbjct: 62 DLFIVSK----------------------KXXYLDLXNIHWPMQFKPG 87
>NADO2_ORYSA (Q7G765) Probable NAD(P)H-dependent oxidoreductase 2 (EC 1.-.-.-)| Length = 322 Score = 78.6 bits (192), Expect = 4e-15 Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 7/115 (6%) Frame = +3 Query: 3 IPSVGLGT-----WQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG- 164 +P +G+GT SE A+ A++ GYRH D A++Y E + A+ + G Sbjct: 18 MPRIGMGTAAFPFTSSEETTA--ALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGL 75 Query: 165 VTTRKDLFITSKLWCTN-HAPEDVPVALDGTLQDLQTDYVDLYLVHWPIRMKKGA 326 V +R D+F+TSKLWC++ HA VP A + TL++L DYVDL LVHWP + G+ Sbjct: 76 VASRADVFVTSKLWCSDLHAGRVVPAARE-TLRNLGMDYVDLLLVHWPATVAPGS 129
>YJ66_YEAST (P47137) Probable oxidoreductase YJR096W (EC 1.-.-.-)| Length = 282 Score = 77.0 bits (188), Expect = 1e-14 Identities = 41/109 (37%), Positives = 61/109 (55%), Gaps = 3/109 (2%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDE--GVTTR 176 IPS+ LGT+ + VY VK GYRH D A +YGNEKE+G + K +E G R Sbjct: 14 IPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNEDPGNHKR 73 Query: 177 KDLFITSKLWCTNHAPEDVPVALDGTLQDLQ-TDYVDLYLVHWPIRMKK 320 +++F T+KLW + + + A+ L ++ Y+DL L+H P+ K Sbjct: 74 EEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPLEGSK 122
>MORA_PSEPU (Q02198) Morphine 6-dehydrogenase (EC 1.1.1.218) (Naloxone| reductase) Length = 295 Score = 73.2 bits (178), Expect = 2e-13 Identities = 38/103 (36%), Positives = 63/103 (61%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKD 182 +P++GLG + + A+ +A+ +GYR ID A+ Y NE ++G ++ + GV R + Sbjct: 15 MPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGEGIR---NSGVD-RAE 70 Query: 183 LFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWPIR 311 +F+T+KL+ ++ E A D +L L DYVDLYL+HWP + Sbjct: 71 MFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWPTK 113
>YOF5_CAEEL (Q09632) Probable oxidoreductase ZK1290.5 in chromosome II (EC| 1.-.-.-) Length = 321 Score = 68.6 bits (166), Expect = 4e-12 Identities = 40/102 (39%), Positives = 63/102 (61%), Gaps = 1/102 (0%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVYAAVK-AGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRK 179 +P +GLGT S G DAV ++K GYR ID A+ YG EK++G A+K R+ Sbjct: 13 MPLIGLGTTHSG-GYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAVKNC----SVPRE 67 Query: 180 DLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 ++F+++KLW + ++V A + + LQTDY+D+Y++H P Sbjct: 68 EMFLSTKLWPVD-CGDEVYNAFQTSCEKLQTDYLDMYMIHMP 108
>DKGB_CORSS (P15339) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 276 Score = 58.2 bits (139), Expect = 5e-09 Identities = 35/99 (35%), Positives = 54/99 (54%), Gaps = 2/99 (2%) Frame = +3 Query: 15 GLGTW--QSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKDLF 188 GLGT+ + + GV A+ AA+ +GYR +D A Y NE E+G A++ R +L Sbjct: 18 GLGTYNLRGDEGVA--AMVAAIDSGYRLLDTAVNYENESEVGRAVRA----SSVDRDELI 71 Query: 189 ITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 + SK+ H + ++ G+L L D +DL L+HWP Sbjct: 72 VASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP 110
>YEAE_ECOLI (P76234) Hypothetical protein yeaE| Length = 284 Score = 56.6 bits (135), Expect = 1e-08 Identities = 37/108 (34%), Positives = 58/108 (53%), Gaps = 8/108 (7%) Frame = +3 Query: 3 IPSVGLGTWQ-----SEPGVVGDAVYAAVKAGYRHIDCAQVY---GNEKEIGFALKKVFD 158 +P+VG GTW S+ A+ A ++ G ID A++Y G EK +G AL + Sbjct: 14 LPAVGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGL-- 71 Query: 159 EGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 302 R+ +F+ SK++ N + A + +L+ L TDY+DLYL+HW Sbjct: 72 -----REKVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHW 114
>GS69_BACSU (P80874) General stress protein 69 (EC 1.1.1.-) (GSP69) (AKR11B)| Length = 331 Score = 47.0 bits (110), Expect = 1e-05 Identities = 35/112 (31%), Positives = 53/112 (47%), Gaps = 14/112 (12%) Frame = +3 Query: 12 VGLGTWQSEPGVVG--------DAVYAAVKAGYRHIDCAQVYG---NEKEIGFALKKVF- 155 +GLGTW + G + + AA+ G ID A YG +E+ +G A+K+ Sbjct: 16 IGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVGKAIKEYGK 75 Query: 156 -DEGVTTRKDLFITSKLWCTNHAPED-VPVALDGTLQDLQTDYVDLYLVHWP 305 D+ + K HA + ++ +L+ LQTDY+DLY VHWP Sbjct: 76 RDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLYQVHWP 127
>YDJG_ECOLI (P77256) Hypothetical oxidoreductase ydjG (EC 1.-.-.-)| Length = 326 Score = 41.6 bits (96), Expect = 5e-04 Identities = 35/122 (28%), Positives = 52/122 (42%), Gaps = 25/122 (20%) Frame = +3 Query: 12 VGLGTWQSEPG----------VVGDAVYAAVKAGYRHIDCAQVYG---NEKEIGFALKKV 152 +GLGTW G + D + A + G ID A Y +E +G ALKK+ Sbjct: 16 MGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIVGQALKKL 75 Query: 153 FDEGVTT----------RKDLF--ITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLV 296 E V + LF + + N +PE + + +LQ L DY+D+Y+ Sbjct: 76 PREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAASLQRLGIDYIDIYMT 135 Query: 297 HW 302 HW Sbjct: 136 HW 137
>IOLS_BACSU (P46336) Protein iolS (EC 1.1.1.-) (Vegetative protein 147)| (VEG147) (AKR11A) Length = 310 Score = 41.6 bits (96), Expect = 5e-04 Identities = 26/95 (27%), Positives = 52/95 (54%), Gaps = 11/95 (11%) Frame = +3 Query: 54 DAVYAAVKAGYRHIDCAQVYG---NEKEIGFALKKVFDEGVTTRKDLFITSKL------- 203 + V A++ G +D A +YG +E+ IG L++ R+D+ I +K Sbjct: 39 ELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLREF------NREDVVIATKAAHRKQGN 92 Query: 204 -WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 + +++P+ + ++D +L+ L TDY+DL+ +H+P Sbjct: 93 DFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFP 127
>KCAB1_RABIT (Q9XT31) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 419 Score = 40.0 bits (92), Expect = 0.001 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D V A ++G D A+VY K L + + Sbjct: 101 VSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKKKG 159 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+KL+ A + + L G+LQ LQ +YVD+ + P Sbjct: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP 212
>KCAB1_HUMAN (Q14722) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 419 Score = 40.0 bits (92), Expect = 0.001 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D V A ++G D A+VY K L + + Sbjct: 101 VSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKKKG 159 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+KL+ A + + L G+LQ LQ +YVD+ + P Sbjct: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP 212
>YCCK_BACSU (P46905) Hypothetical oxidoreductase yccK (EC 1.-.-.-)| Length = 310 Score = 40.0 bits (92), Expect = 0.001 Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 11/95 (11%) Frame = +3 Query: 54 DAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPEDV 233 D V A+ G ID A +YG + + V + GV R +L I +K H D Sbjct: 40 DLVRTALDGGVNFIDTAFIYGLGRSEELIGEVVQERGV--RNELIIATK---GAHKEVDG 94 Query: 234 PVALDGT-----------LQDLQTDYVDLYLVHWP 305 + LD + L+ L+TDY+DLY VH+P Sbjct: 95 SIELDNSREFLRSEVEKSLKRLKTDYIDLYYVHFP 129
>KCAB1_MUSPU (Q28528) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 408 Score = 40.0 bits (92), Expect = 0.001 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D V A ++G D A+VY K L + + Sbjct: 90 VSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKKKG 148 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+KL+ A + + L G+LQ LQ +YVD+ + P Sbjct: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP 201
>KCAB1_RAT (P63144) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 40.0 bits (92), Expect = 0.001 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D V A ++G D A+VY K L + + Sbjct: 83 VSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKKKG 141 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+KL+ A + + L G+LQ LQ +YVD+ + P Sbjct: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP 194
>KCAB1_MOUSE (P63143) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 40.0 bits (92), Expect = 0.001 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D V A ++G D A+VY K L + + Sbjct: 83 VSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKKKG 141 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+KL+ A + + L G+LQ LQ +YVD+ + P Sbjct: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP 194
>KCAB1_BOVIN (Q4PJK1) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 40.0 bits (92), Expect = 0.001 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D V A ++G D A+VY K L + + Sbjct: 83 VSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKKKG 141 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+KL+ A + + L G+LQ LQ +YVD+ + P Sbjct: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP 194
>KCAB1_CHICK (Q9PWR1) Voltage-gated potassium channel beta-1 subunit (K(+)| channel beta-1 subunit) (Kv-beta-1) Length = 401 Score = 37.7 bits (86), Expect = 0.007 Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 15/116 (12%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAV-----YAAVKAGYRHIDCAQVYGNEKE---IGFALKKVFD 158 + +GLGTW + G + D V A ++G D A+VY K +G LKK Sbjct: 83 VSCLGLGTWVTFGGQISDEVAEQLMTIAYESGVNLFDTAEVYAAGKAEVILGNILKK--- 139 Query: 159 EGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 +G R L IT+KL+ A + + L +LQ LQ +YVD+ + P Sbjct: 140 KG-WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLRASLQRLQLEYVDVVFANRP 194
>TAS_SHIFL (P0A9T5) Protein tas| Length = 346 Score = 37.7 bits (86), Expect = 0.007 Identities = 16/29 (55%), Positives = 22/29 (75%) Frame = +3 Query: 225 EDVPVALDGTLQDLQTDYVDLYLVHWPIR 311 +++ AL +L+ LQTDY+DLY VHWP R Sbjct: 108 KNIREALHDSLKRLQTDYLDLYQVHWPQR 136
>TAS_ECOLI (P0A9T4) Protein tas| Length = 346 Score = 37.7 bits (86), Expect = 0.007 Identities = 16/29 (55%), Positives = 22/29 (75%) Frame = +3 Query: 225 EDVPVALDGTLQDLQTDYVDLYLVHWPIR 311 +++ AL +L+ LQTDY+DLY VHWP R Sbjct: 108 KNIREALHDSLKRLQTDYLDLYQVHWPQR 136
>ALKE_BABBO (P40690) Aldo-keto reductase (Fragment)| Length = 285 Score = 36.2 bits (82), Expect = 0.021 Identities = 14/29 (48%), Positives = 21/29 (72%) Frame = +3 Query: 225 EDVPVALDGTLQDLQTDYVDLYLVHWPIR 311 +++ A+DG+L L TDY+DL +HWP R Sbjct: 29 DNILKAVDGSLSRLNTDYIDLLQLHWPDR 57
>DHGP_ASPNG (P55804) NADP(+)-dependent glycerol dehydrogenase (EC 1.1.1.72)| (Fragments) Length = 99 Score = 35.8 bits (81), Expect = 0.027 Identities = 13/22 (59%), Positives = 17/22 (77%) Frame = +3 Query: 264 LQTDYVDLYLVHWPIRMKKGAG 329 L+ DY+DL+LVHWPI +K G Sbjct: 20 LKVDYIDLFLVHWPIAAEKAIG 41
>KCAB_ORYSA (Q40648) Probable voltage-gated potassium channel beta subunit| (K(+) channel beta subunit) Length = 328 Score = 35.0 bits (79), Expect = 0.046 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 7/83 (8%) Frame = +3 Query: 78 AGYRHIDCAQVYGNEKEIGFALKKVFDEGVTTRKDLFITSKLWCTNHAPED-------VP 236 AG D A+VY N + + + D G R D+ +++KL+ P D + Sbjct: 43 AGVNFFDNAEVYANGRAEEIMGQAMRDLG-WRRSDVVVSTKLFWGGQGPNDKGLSRKHIV 101 Query: 237 VALDGTLQDLQTDYVDLYLVHWP 305 L G+L+ L DYVD+ H P Sbjct: 102 EGLRGSLKRLDMDYVDVVYCHRP 124
>KCAB3_XENLA (Q9PTM4) Voltage-gated potassium channel beta-3 subunit (K(+)| channel beta-3 subunit) (Kv-beta-3) Length = 401 Score = 35.0 bits (79), Expect = 0.046 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 15/110 (13%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAVY-----AAVKAGYRHIDCAQVYGN---EKEIGFALKKVFD 158 + +GLGTW + + D V A + G D A+VY E+ +G LKK Sbjct: 83 VSCLGLGTWVTFGSQISDEVAENLMTVAYEHGVNLFDTAEVYAAGRAERTLGKILKKK-- 140 Query: 159 EGVTTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDL 287 R +T+K++ A + + L G+L+ LQ DYVD+ Sbjct: 141 --EWRRSSYVVTTKIYWGGQAETERGLSRKHIIEGLRGSLERLQLDYVDI 188
>AAD6_YEAST (P43547) Putative aryl-alcohol dehydrogenase AAD6 (EC 1.1.1.-)| Length = 212 Score = 35.0 bits (79), Expect = 0.046 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 16/99 (16%) Frame = +3 Query: 54 DAVYAAVKAGYRHIDCAQVYGNEKE---IG--FALKKVFDEGVTTRKDLFIT-------- 194 DA Y +AG ID A Y NE+ IG +K+ D+ V K F T Sbjct: 60 DAFY---EAGGNFIDTANNYQNEQSEAWIGEWMVSRKLRDQIVIATK--FTTDYKKYDVG 114 Query: 195 ---SKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 302 S +C NH + V++ +L+ LQTD++D+ VHW Sbjct: 115 GGKSANYCGNHK-RSLHVSVRDSLRKLQTDWIDILYVHW 152
>YQKF_BACSU (P54569) Hypothetical oxidoreductase yqkF (EC 1.-.-.-)| Length = 306 Score = 34.7 bits (78), Expect = 0.060 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 15/114 (13%) Frame = +3 Query: 3 IPSVGLGTWQ--SEPGVVGDAVYAAVKAGYRHIDCAQVYG---NEKEIGFALKKVFDEGV 167 I VGLG +E + A++ G ++D A +Y NE+ +G A++ Sbjct: 13 ISEVGLGCMSLGTEKNKALSILDEAIELGINYLDTADLYDRGRNEEIVGDAIQN------ 66 Query: 168 TTRKDLFITSKL----------WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVH 299 R D+ + +K W + + + A+ +L L+TDY+DLY +H Sbjct: 67 -RRHDIILATKAGNRWDDGSEGWYWDPSKAYIKEAVKKSLTRLKTDYIDLYQLH 119
>AAD14_YEAST (P42884) Putative aryl-alcohol dehydrogenase AAD14 (EC 1.1.1.-)| Length = 376 Score = 34.7 bits (78), Expect = 0.060 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 14/97 (14%) Frame = +3 Query: 54 DAVYAAVKAGYRHIDCAQVYGNEKE---IG--FALKKVFDEGVTTRKDLFITSKL----- 203 DA Y +AG ID A Y NE+ IG A +K+ D+ V K K Sbjct: 60 DAFY---EAGGNCIDTANSYQNEESEIWIGEWMASRKLRDQIVIATKFTGDYKKYEVGGG 116 Query: 204 ----WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 302 +C NH + V++ +L+ LQTD++D+ +HW Sbjct: 117 KSANYCGNHK-RSLHVSVRDSLRKLQTDWIDILYIHW 152
>AAD4_YEAST (Q07747) Probable aryl-alcohol dehydrogenase AAD4 (EC 1.1.1.-)| Length = 329 Score = 33.9 bits (76), Expect = 0.10 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 14/97 (14%) Frame = +3 Query: 54 DAVYAAVKAGYRHIDCAQVYGNEKE---IGFALK--KVFDEGVTTRKDLFITSKL----- 203 DA Y +AG ID A Y NE+ IG +K K+ D+ V K K Sbjct: 14 DAFY---EAGGNCIDTANSYQNEESEIWIGEWMKSRKLRDQIVIATKFTGDYKKYEVGGG 70 Query: 204 ----WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 302 +C NH + V++ +L+ LQTD++D+ VHW Sbjct: 71 KSANYCGNHK-HSLHVSVRDSLRKLQTDWIDILYVHW 106
>KCAB2_XENLA (Q9PTM5) Voltage-gated potassium channel beta-2 subunit (K(+)| channel beta-2 subunit) (Kv-beta-2) Length = 367 Score = 33.5 bits (75), Expect = 0.13 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGD-----AVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D + A G D A+VY K L + + Sbjct: 49 VSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKKKG 107 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+K++ A + + L +L+ LQ DYVD+ + P Sbjct: 108 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLDYVDVVFANRP 160
>Y2320_MYCBO (P63485) Hypothetical protein Mb2320| Length = 323 Score = 33.1 bits (74), Expect = 0.18 Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 14/115 (12%) Frame = +3 Query: 3 IPSVGLGTWQ-----------SEPGVVGDAVYAAVKAGYRHIDCAQVYG---NEKEIGFA 140 + +GLGTWQ G D V A G D A++YG +E+ +G A Sbjct: 12 VSRIGLGTWQFGSREWGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLGKSERILGEA 71 Query: 141 LKKVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 L R ++ + SK++ P + + + LQ + + LY +H P Sbjct: 72 LG-------DDRTEVVVASKVFPVAPFPAVIKNRERASARRLQLNRIPLYQIHQP 119
>Y2298_MYCTU (P63484) Hypothetical protein Rv2298/MT2355| Length = 323 Score = 33.1 bits (74), Expect = 0.18 Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 14/115 (12%) Frame = +3 Query: 3 IPSVGLGTWQ-----------SEPGVVGDAVYAAVKAGYRHIDCAQVYG---NEKEIGFA 140 + +GLGTWQ G D V A G D A++YG +E+ +G A Sbjct: 12 VSRIGLGTWQFGSREWGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLGKSERILGEA 71 Query: 141 LKKVFDEGVTTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 L R ++ + SK++ P + + + LQ + + LY +H P Sbjct: 72 LG-------DDRTEVVVASKVFPVAPFPAVIKNRERASARRLQLNRIPLYQIHQP 119
>YAKC_SCHPO (Q09923) Aldo-keto reductase yakc [NADP+] (EC 1.1.1.-)| Length = 340 Score = 32.0 bits (71), Expect = 0.39 Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 13/90 (14%) Frame = +3 Query: 69 AVKAGYRHIDCAQVYG---NEKEIGFALKKVFDEGVTTRKDLFITSKLW----------C 209 A G D + +YG NE+ IG K+ RK++F+ +K Sbjct: 42 AADLGCTFWDSSDMYGFGANEECIGRWFKQT-----GRRKEIFLATKFGYEKNPETGELS 96 Query: 210 TNHAPEDVPVALDGTLQDLQTDYVDLYLVH 299 N+ P+ + ALD +L+ L D +DLY VH Sbjct: 97 LNNEPDYIEKALDLSLKRLGIDCIDLYYVH 126
>KCAB2_RAT (P62483) Voltage-gated potassium channel beta-2 subunit (K(+)| channel beta-2 subunit) (Kv-beta-2) Length = 367 Score = 32.0 bits (71), Expect = 0.39 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGD-----AVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D + A G D A+VY K L + + Sbjct: 49 VSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKKKG 107 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+K++ A + + L +L+ LQ +YVD+ + P Sbjct: 108 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>KCAB2_MOUSE (P62482) Voltage-gated potassium channel beta-2 subunit (K(+)| channel beta-2 subunit) (Kv-beta-2) (Neuroimmune protein F5) Length = 367 Score = 32.0 bits (71), Expect = 0.39 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGD-----AVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D + A G D A+VY K L + + Sbjct: 49 VSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKKKG 107 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+K++ A + + L +L+ LQ +YVD+ + P Sbjct: 108 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>KCAB2_HUMAN (Q13303) Voltage-gated potassium channel beta-2 subunit (K(+)| channel beta-2 subunit) (Kv-beta-2) (HKvbeta2) Length = 367 Score = 32.0 bits (71), Expect = 0.39 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGD-----AVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D + A G D A+VY K L + + Sbjct: 49 VSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKKKG 107 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+K++ A + + L +L+ LQ +YVD+ + P Sbjct: 108 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>KCAB2_BOVIN (Q27955) Voltage-gated potassium channel beta-2 subunit (K(+)| channel beta-2 subunit) (Kv-beta-2) Length = 367 Score = 32.0 bits (71), Expect = 0.39 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 12/113 (10%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGD-----AVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV 167 + +GLGTW + G + D + A G D A+VY K L + + Sbjct: 49 VSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKKKG 107 Query: 168 TTRKDLFITSKLWCTNHAPED-------VPVALDGTLQDLQTDYVDLYLVHWP 305 R L IT+K++ A + + L +L+ LQ +YVD+ + P Sbjct: 108 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>YCSN_BACSU (P42972) Hypothetical oxidoreductase ycsN (EC 1.-.-.-)| Length = 300 Score = 32.0 bits (71), Expect = 0.39 Identities = 23/114 (20%), Positives = 47/114 (41%), Gaps = 18/114 (15%) Frame = +3 Query: 18 LGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGVTT----RKDL 185 L W + + + G D A +YG G+ +K+F + R+++ Sbjct: 22 LNEWNYSDAELLSLIEWCIDHGITTFDHADIYG-----GYTCEKLFGNALALSPGLRENI 76 Query: 186 FITSKLWCTNHAPE--------------DVPVALDGTLQDLQTDYVDLYLVHWP 305 + +K +PE + +++ +L +L+TDY+D+ L+H P Sbjct: 77 ELVTKCGIVLESPERPAHRSHHYNTSKSHILASVEQSLMNLRTDYIDMLLIHRP 130
>AAD3_YEAST (P25612) Putative aryl-alcohol dehydrogenase AAD3 (EC 1.1.1.-)| Length = 363 Score = 32.0 bits (71), Expect = 0.39 Identities = 13/33 (39%), Positives = 22/33 (66%) Frame = +3 Query: 204 WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 302 +C NH + V++ +L+ LQTD++D+ VHW Sbjct: 118 YCGNHK-RSLHVSVRDSLRKLQTDWIDILYVHW 149
>AAD10_YEAST (P47182) Putative aryl-alcohol dehydrogenase AAD10 (EC 1.1.1.-)| Length = 288 Score = 31.6 bits (70), Expect = 0.51 Identities = 13/33 (39%), Positives = 22/33 (66%) Frame = +3 Query: 204 WCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 302 +C NH + V++ +L+ LQTD++D+ VHW Sbjct: 33 FCGNHK-RSLHVSVRDSLRKLQTDWIDILYVHW 64
>ABCC9_MOUSE (P70170) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1546 Score = 31.2 bits (69), Expect = 0.67 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 5/54 (9%) Frame = +3 Query: 174 RKDLFITSKLWCTNHAP-----EDVPVALDGTLQDLQTDYVDLYLVHWPIRMKK 320 R + +T KL HA +D V +GTL+D+QT V+LY HW M + Sbjct: 861 RTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELY-EHWKTLMNR 913
>ABCC9_RAT (Q63563) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1545 Score = 31.2 bits (69), Expect = 0.67 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 5/54 (9%) Frame = +3 Query: 174 RKDLFITSKLWCTNHAP-----EDVPVALDGTLQDLQTDYVDLYLVHWPIRMKK 320 R + +T KL HA +D V +GTL+D+QT V+LY HW M + Sbjct: 860 RTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELY-EHWKTLMNR 912
>ABCC9_RABIT (P82451) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1549 Score = 30.8 bits (68), Expect = 0.87 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 5/51 (9%) Frame = +3 Query: 183 LFITSKLWCTNHAP-----EDVPVALDGTLQDLQTDYVDLYLVHWPIRMKK 320 + +T KL HA +D V +GTL+D+QT V+LY HW M + Sbjct: 867 VLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELY-EHWKTLMNR 916
>ABCC9_HUMAN (O60706) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1549 Score = 30.8 bits (68), Expect = 0.87 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 5/51 (9%) Frame = +3 Query: 183 LFITSKLWCTNHAP-----EDVPVALDGTLQDLQTDYVDLYLVHWPIRMKK 320 + +T KL HA +D V +GTL+D+QT V+LY HW M + Sbjct: 867 VLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELY-EHWKTLMNR 916
>NORA_ASPPA (Q00258) Norsolorinic acid reductase (EC 1.1.1.-)| Length = 388 Score = 30.4 bits (67), Expect = 1.1 Identities = 14/29 (48%), Positives = 21/29 (72%) Frame = +3 Query: 213 NHAPEDVPVALDGTLQDLQTDYVDLYLVH 299 NHA + + +++ +LQ LQTDY+DL VH Sbjct: 121 NHA-KSLRLSVKASLQKLQTDYIDLLYVH 148
>NORA_ASPFL (Q00049) Norsolorinic acid reductase (EC 1.1.1.-)| Length = 388 Score = 30.4 bits (67), Expect = 1.1 Identities = 14/29 (48%), Positives = 21/29 (72%) Frame = +3 Query: 213 NHAPEDVPVALDGTLQDLQTDYVDLYLVH 299 NHA + + +++ +LQ LQTDY+DL VH Sbjct: 121 NHA-KSLRLSVKASLQKLQTDYIDLLYVH 148
>VIE1_MCMVS (P11210) Immediate-early protein 1 (IE1) (Immediate-early| phosphoprotein PP89) Length = 595 Score = 30.0 bits (66), Expect = 1.5 Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 3/85 (3%) Frame = +3 Query: 66 AAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV-TTRKDLFITSKL--WCTNHAPEDVP 236 A+V A RH+D +VY ++K K+ + G T R DL + L + + E+ Sbjct: 17 ASVNAHGRHLDENRVYPSDKVPAHVANKILESGTETVRCDLTLEDMLGDYEYDDPTEEEK 76 Query: 237 VALDGTLQDLQTDYVDLYLVHWPIR 311 + +D + D D+ + H +R Sbjct: 77 ILMDRIADHVGNDNSDMAIKHAAVR 101
>ARK71_RAT (P38918) Aflatoxin B1 aldehyde reductase member 1 (EC 1.-.-.-)| (AFB1-AR) (rAFAR1) Length = 327 Score = 29.6 bits (65), Expect = 1.9 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 6/89 (6%) Frame = +3 Query: 57 AVYAAVKAGYRHIDCAQVYGNEK------EIGFALKKVFDEGVTTRKDLFITSKLWCTNH 218 +V A ++ G+ ID A VY N + ++G L + + K + ++ Sbjct: 27 SVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCKVKIATK----AAPMFGKTL 82 Query: 219 APEDVPVALDGTLQDLQTDYVDLYLVHWP 305 P DV L+ +L+ LQ VDL+ +H+P Sbjct: 83 KPADVRFQLETSLKRLQCPRVDLFYLHFP 111
>AAD_PHACH (Q01752) Aryl-alcohol dehydrogenase [NADP+] (EC 1.1.1.91) (AAD)| Length = 385 Score = 29.6 bits (65), Expect = 1.9 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 16/112 (14%) Frame = +3 Query: 15 GLGTWQSEPGV-VGDAVYAAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEG------VTT 173 G+GT E + DA Y AG ID A VY +E F + + G V T Sbjct: 46 GMGTMDKEASFKLLDAFY---NAGGNFIDTANVYQDETSEEFIGEWMEARGNRDQMVVAT 102 Query: 174 RKDLF---------ITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHW 302 + L I K ++ + + +++ +L+ L+T Y+D++ VH+ Sbjct: 103 KYSLVYKRGASFEEIPQKTQYVGNSLKSMHISVHDSLRKLRTSYIDIFYVHF 154
>DLX4_HUMAN (Q92988) Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1)| Length = 240 Score = 29.6 bits (65), Expect = 1.9 Identities = 11/26 (42%), Positives = 18/26 (69%) Frame = -1 Query: 265 RSWSVPSSATGTSSGAWLVHHSLEVM 188 ++ ++P+S G S GAW HHS +V+ Sbjct: 209 KAGTLPTSGYGNSFGAWYQHHSSDVL 234
>YAJO_ECOLI (P77735) Hypothetical oxidoreductase yajO (EC 1.-.-.-)| Length = 324 Score = 28.9 bits (63), Expect = 3.3 Identities = 27/110 (24%), Positives = 45/110 (40%), Gaps = 12/110 (10%) Frame = +3 Query: 6 PSVGLGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYGN---EKEIGFALKKVFDEGVTTR 176 P G W + A++ G D A Y + E+ +G AL+ R Sbjct: 26 PDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDF-----ARR 80 Query: 177 KDLFITSKLWCTNHAPEDVPVAL---------DGTLQDLQTDYVDLYLVH 299 +D+ + +K++ H D+P L D +L+ L DYVD+ +H Sbjct: 81 EDVVVATKVF---HRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIH 127
>CROB_LEPLU (P49261) Rho beta-crystallin (Fragments)| Length = 89 Score = 28.9 bits (63), Expect = 3.3 Identities = 11/20 (55%), Positives = 15/20 (75%) Frame = +3 Query: 3 IPSVGLGTWQSEPGVVGDAV 62 +P +GLGTWQ+ PG V A+ Sbjct: 1 MPILGLGTWQAPPGKVEKAI 20 Score = 27.7 bits (60), Expect = 7.4 Identities = 9/18 (50%), Positives = 15/18 (83%) Frame = +3 Query: 264 LQTDYVDLYLVHWPIRMK 317 ++ DY+DLYL+H+P+ K Sbjct: 20 IKLDYLDLYLIHFPMGFK 37
>VIE3_MCMVS (P29832) Immediate-early protein 3 (IE3)| Length = 611 Score = 28.5 bits (62), Expect = 4.3 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 3/81 (3%) Frame = +3 Query: 66 AAVKAGYRHIDCAQVYGNEKEIGFALKKVFDEGV-TTRKDLFITSKL--WCTNHAPEDVP 236 A+V A RH+D +VY ++K K+ + G T R DL + L + + E+ Sbjct: 17 ASVNAHGRHLDENRVYPSDKVPAHVANKILESGTETVRCDLTLEDMLGDYEYDDPTEEEK 76 Query: 237 VALDGTLQDLQTDYVDLYLVH 299 + +D + D D+ + H Sbjct: 77 ILMDRIADHVGNDNSDMAIKH 97
>LGRC_BREPA (Q70LM5) Linear gramicidin synthetase subunit C [Includes:| ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tr Length = 7756 Score = 28.1 bits (61), Expect = 5.6 Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 2/44 (4%) Frame = -1 Query: 247 SSATGTSSGAWLVHHSLEVMKRSFRVVTPSS--NTFLRANPISF 122 S +TGT G VH + + + R +P S + FL+A+ +SF Sbjct: 620 SGSTGTPKGVLAVHRGVVRLGQKTRTTSPISEADVFLQASTVSF 663
>TOC34_PEA (Q41009) Translocase of chloroplast 34 (EC 3.6.5.-) (34 kDa| chloroplast outer envelope protein) (GTP-binding protein OEP34) (GTP-binding protein IAP34) Length = 310 Score = 28.1 bits (61), Expect = 5.6 Identities = 13/40 (32%), Positives = 25/40 (62%), Gaps = 5/40 (12%) Frame = -3 Query: 191 DEKIFPSGYALVEHLLESESDLFL-----VAVDLSTVDVP 87 DEK+ P+G A + HL+++ +++ L + VD + +D P Sbjct: 221 DEKVLPNGIAWIPHLVQTITEVALNKSESIFVDKNLIDGP 260
>POLR_TYMVC (P28477) RNA replicase polyprotein (EC 2.7.7.48)| Length = 1844 Score = 28.1 bits (61), Expect = 5.6 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 4/45 (8%) Frame = -1 Query: 262 SWSVPSSATGTSSGAWLVHHSLEVM----KRSFRVVTPSSNTFLR 140 S+ +P+S GTS H ++E SF+ TPSS F++ Sbjct: 52 SYGIPTSGLGTSHHPHAAHKTIETFLLCTHWSFQATTPSSVMFMK 96
>POLR_TYMVA (P20128) RNA replicase polyprotein (EC 2.7.7.48)| Length = 1844 Score = 28.1 bits (61), Expect = 5.6 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 4/45 (8%) Frame = -1 Query: 262 SWSVPSSATGTSSGAWLVHHSLEVM----KRSFRVVTPSSNTFLR 140 S+ +P+S GTS H ++E SF+ TPSS F++ Sbjct: 52 SYGIPTSGLGTSHHPHAAHKTIETFLLCTHWSFQATTPSSVMFMK 96
>POLR_TYMV (P10358) RNA replicase polyprotein (EC 2.7.7.48)| Length = 1844 Score = 28.1 bits (61), Expect = 5.6 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 4/45 (8%) Frame = -1 Query: 262 SWSVPSSATGTSSGAWLVHHSLEVM----KRSFRVVTPSSNTFLR 140 S+ +P+S GTS H ++E SF+ TPSS F++ Sbjct: 52 SYGIPTSGLGTSHHPHAAHKTIETFLLCTHWSFQATTPSSVMFMK 96
>BACH2_MOUSE (P97303) Transcription regulator protein BACH2 (BTB and CNC homolog| 2) Length = 716 Score = 28.1 bits (61), Expect = 5.6 Identities = 14/33 (42%), Positives = 18/33 (54%) Frame = +3 Query: 18 LGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYG 116 L T EPG++GD +Y V+ I C Q YG Sbjct: 433 LATEHQEPGLMGDGMYNQVRP---QIKCEQSYG 462
>BACH2_HUMAN (Q9BYV9) Transcription regulator protein BACH2 (BTB and CNC homolog| 2) Length = 841 Score = 28.1 bits (61), Expect = 5.6 Identities = 14/33 (42%), Positives = 18/33 (54%) Frame = +3 Query: 18 LGTWQSEPGVVGDAVYAAVKAGYRHIDCAQVYG 116 L T EPG++GD +Y V+ I C Q YG Sbjct: 557 LATEHQEPGLMGDGMYNQVRP---QIKCEQSYG 586
>ARK72_MOUSE (Q8CG76) Aflatoxin B1 aldehyde reductase member 2 (EC 1.-.-.-)| Length = 367 Score = 27.7 bits (60), Expect = 7.4 Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 6/106 (5%) Frame = +3 Query: 6 PSVGLGTWQSEPGVVGDAVYAAVKA----GYRHIDCAQVY--GNEKEIGFALKKVFDEGV 167 P+ LGT + + A A+V+A G+ +D A +Y G + I L G Sbjct: 46 PATVLGTMEMGRRMDASASAASVRAFLERGHSELDTAFMYCDGQSENILGGLGLGLGSGD 105 Query: 168 TTRKDLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLYLVHWP 305 T K + + P+ V L+ +L+ LQ VDL+ +H P Sbjct: 106 CTVKIATKANPWEGKSLKPDSVRSQLETSLKRLQCPRVDLFYLHAP 151
>PTPRK_HUMAN (Q15262) Receptor-type tyrosine-protein phosphatase kappa precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) Length = 1439 Score = 27.7 bits (60), Expect = 7.4 Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 12/84 (14%) Frame = +3 Query: 27 WQSEPGVVGDAVYAAVKAGYRHIDCAQVYG------------NEKEIGFALKKVFDEGVT 170 W +E V+ +A + ++GY ID QV + E+ F + + Sbjct: 160 WPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATF-QCIA 218 Query: 171 TRKDLFITSKLWCTNHAPEDVPVA 242 T +D + +KLW ED+PVA Sbjct: 219 TGRDA-VHNKLWLQRRNGEDIPVA 241
>GLT12_DROME (Q8IA44) Putative polypeptide N-acetylgalactosaminyltransferase 12| (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) (pp-GaNTase 12) Length = 563 Score = 27.7 bits (60), Expect = 7.4 Identities = 13/37 (35%), Positives = 19/37 (51%) Frame = +3 Query: 180 DLFITSKLWCTNHAPEDVPVALDGTLQDLQTDYVDLY 290 +L ++ K+WCT VP + G LQ DY+ Y Sbjct: 315 ELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRY 351
>PTPRK_MOUSE (P35822) Receptor-type tyrosine-protein phosphatase kappa precursor| (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) Length = 1457 Score = 27.7 bits (60), Expect = 7.4 Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 12/84 (14%) Frame = +3 Query: 27 WQSEPGVVGDAVYAAVKAGYRHIDCAQVYG------------NEKEIGFALKKVFDEGVT 170 W +E V+ +A + ++GY ID QV + E+ F + + Sbjct: 159 WPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATF-QCIA 217 Query: 171 TRKDLFITSKLWCTNHAPEDVPVA 242 T +D + +KLW ED+PVA Sbjct: 218 TGRDA-VHNKLWLQRRNGEDIPVA 240
>PAR1_XENLA (P47749) Proteinase-activated receptor 1 precursor (PAR-1)| (Thrombin receptor) Length = 420 Score = 27.3 bits (59), Expect = 9.6 Identities = 13/34 (38%), Positives = 17/34 (50%) Frame = -1 Query: 334 LKPAPFFIRIGQCTRYRST*SVCRSWSVPSSATG 233 L P ++ QC RY + CR S P S+TG Sbjct: 361 LDPLIYYYASSQCQRYLYSLLCCRKVSEPGSSTG 394
>NADC_ECOLI (P30011) Nicotinate-nucleotide pyrophosphorylase [carboxylating]| (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) Length = 296 Score = 27.3 bits (59), Expect = 9.6 Identities = 13/37 (35%), Positives = 22/37 (59%) Frame = -3 Query: 335 VEAGAFLHPDRPVHEV*IHVVGLQVLERAVQRHRDVL 225 VE ++LHPD PV + V L+ L+ A++ D++ Sbjct: 199 VEKASWLHPDAPVE---VEVENLEELDEALKAGADII 232
>STCJ_EMENI (Q00681) Putative sterigmatocystin biosynthesis fatty acid synthase| alpha subunit Length = 1559 Score = 27.3 bits (59), Expect = 9.6 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Frame = +3 Query: 30 QSEPGVV-GDAVYAAVKAGYRHIDCAQVYGNEKEIGFAL 143 Q P V+ GDA+ AA KAG +I + YG++ + AL Sbjct: 1506 QGAPSVLHGDALAAAQKAGLDNIQLSLSYGDDCVVAVAL 1544 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 41,066,653 Number of Sequences: 219361 Number of extensions: 706572 Number of successful extensions: 2531 Number of sequences better than 10.0: 142 Number of HSP's better than 10.0 without gapping: 2407 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2485 length of database: 80,573,946 effective HSP length: 89 effective length of database: 61,050,817 effective search space used: 1465219608 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
