ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bast61f02 |
|---|---|
| Clone Library Name | barley_pub |
>MDR1_ARATH (Q9ZR72) Multidrug resistance protein 1 (P-glycoprotein 1) (AtPgp1)| Length = 1286 Score = 204 bits (519), Expect = 4e-53 Identities = 105/136 (77%), Positives = 111/136 (81%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 LIG+SSAAL+FNT+QH FWD VGENLTKRVREKML+AVL+NEMAWFD E N SA IAARL Sbjct: 747 LIGLSSAALVFNTLQHSFWDIVGENLTKRVREKMLSAVLKNEMAWFDQEENESARIAARL 806 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMF 360 ALDA NVRSAIGDRISVIVQN+ALMLVACTAGFVLQWR TVLQKMF Sbjct: 807 ALDANNVRSAIGDRISVIVQNTALMLVACTAGFVLQWRLALVLVAVFPVVVAATVLQKMF 866 Query: 361 MKGFSGDLEGAHAKAT 408 M GFSGDLE AHAK T Sbjct: 867 MTGFSGDLEAAHAKGT 882
>MDR11_ARATH (Q9LJX0) Multidrug resistance protein 11 (P-glycoprotein 19)| Length = 1252 Score = 112 bits (279), Expect = 3e-25 Identities = 58/135 (42%), Positives = 82/135 (60%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 IG A+ +QH F+ +GENLT RVR ML+A+LRNE+ WFD + + S+ IAARLA Sbjct: 735 IGAGLYAVGAYLIQHYFFSIMGENLTTRVRRMMLSAILRNEVGWFDEDEHNSSLIAARLA 794 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFM 363 DA +V+SAI +RISVI+QN +L + F+++WR Q++ + Sbjct: 795 TDAADVKSAIAERISVILQNMTSLLTSFIVAFIVEWRVSLLILGTFPLLVLANFAQQLSL 854 Query: 364 KGFSGDLEGAHAKAT 408 KGF+GD AHAK + Sbjct: 855 KGFAGDTAKAHAKTS 869 Score = 41.6 bits (96), Expect = 5e-04 Identities = 22/80 (27%), Positives = 39/80 (48%) Frame = +1 Query: 55 WDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 W GE +R+K L AVL+ ++ +FD +A + I ++ D V+ AI +++ Sbjct: 108 WMYSGERQVAALRKKYLEAVLKQDVGFFDTDAR-TGDIVFSVSTDTLLVQDAISEKVGNF 166 Query: 235 VQNSALMLVACTAGFVLQWR 294 + + L GFV W+ Sbjct: 167 IHYLSTFLAGLVVGFVSAWK 186
>MDR12_ARATH (Q9C7F2) Multidrug resistance protein 12 (P-glycoprotein 14)| Length = 1247 Score = 100 bits (248), Expect = 1e-21 Identities = 48/123 (39%), Positives = 72/123 (58%) Frame = +1 Query: 40 VQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGD 219 +QH F+ +GE LT RVR + +A+L NE+ WFD++ N + + + LA DA VRSAI D Sbjct: 743 LQHYFYTLMGERLTSRVRLSLFSAILSNEIGWFDLDENNTGSLTSILAADATLVRSAIAD 802 Query: 220 RISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGFSGDLEGAHA 399 R+S IVQN +L + A F WR ++ +++F+KGF GD A++ Sbjct: 803 RLSTIVQNLSLTITALALAFFYSWRVAAVVTACFPLLIAASLTEQLFLKGFGGDYTRAYS 862 Query: 400 KAT 408 +AT Sbjct: 863 RAT 865 Score = 42.0 bits (97), Expect = 3e-04 Identities = 24/80 (30%), Positives = 40/80 (50%) Frame = +1 Query: 55 WDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 W GE T R+R L ++L ++ +FD EA S I ++ DA V+ AIGD+ + Sbjct: 115 WMQTGERQTARLRINYLKSILAKDITFFDTEARDSNFIF-HISSDAILVQDAIGDKTGHV 173 Query: 235 VQNSALMLVACTAGFVLQWR 294 ++ + GF+ W+ Sbjct: 174 LRYLCQFIAGFVIGFLSVWQ 193
>MDR15_ARATH (Q9C7F8) Putative multidrug resistance protein 15 (P-glycoprotein 13)| Length = 1245 Score = 99.0 bits (245), Expect = 2e-21 Identities = 47/123 (38%), Positives = 72/123 (58%) Frame = +1 Query: 40 VQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGD 219 +QH F+ +GE LT RVR + +A+L NE+ WFD++ N + + + LA DA VRSA+ D Sbjct: 741 LQHYFYTLMGERLTSRVRLSLFSAILSNEIGWFDLDENNTGSLTSILAADATLVRSALAD 800 Query: 220 RISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGFSGDLEGAHA 399 R+S IVQN +L + A F WR ++ +++F+KGF GD A++ Sbjct: 801 RLSTIVQNLSLTVTALALAFFYSWRVAAVVTACFPLLIAASLTEQLFLKGFGGDYTRAYS 860 Query: 400 KAT 408 +AT Sbjct: 861 RAT 863 Score = 42.7 bits (99), Expect = 2e-04 Identities = 23/80 (28%), Positives = 42/80 (52%) Frame = +1 Query: 55 WDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 W GE T R+R L ++L ++ +FD EA S ++ ++ DA V+ AIGD+ + Sbjct: 114 WMQTGERQTARLRINYLKSILAKDITFFDTEARDS-NLIFHISSDAILVQDAIGDKTDHV 172 Query: 235 VQNSALMLVACTAGFVLQWR 294 ++ + + GF+ W+ Sbjct: 173 LRYLSQFIAGFVIGFLSVWQ 192
>MDR2_ARATH (Q8LPK2) Multidrug resistance protein 2 (P-glycoprotein 2)| Length = 1233 Score = 98.6 bits (244), Expect = 3e-21 Identities = 47/131 (35%), Positives = 77/131 (58%) Frame = +1 Query: 13 SSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 S L+ T++H+ + T+GE LT RVRE M A+L+NE+ WFD N S+ +A+RL DA Sbjct: 720 SVITLIVYTIEHICFGTMGERLTLRVRENMFRAILKNEIGWFDEVDNTSSMLASRLESDA 779 Query: 193 QNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGF 372 +++ + DR ++++QN L++ + F+L WR + +K+FM+G+ Sbjct: 780 TLLKTIVVDRSTILLQNLGLVVTSFIIAFILNWRLTLVVLATYPLVISGHISEKLFMQGY 839 Query: 373 SGDLEGAHAKA 405 GDL A+ KA Sbjct: 840 GGDLNKAYLKA 850
>MDR14_ARATH (Q9M3B9) Multidrug resistance protein 14 (P-glycoprotein 20)| Length = 1408 Score = 97.4 bits (241), Expect = 7e-21 Identities = 47/133 (35%), Positives = 77/133 (57%) Frame = +1 Query: 10 MSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALD 189 M ++ N +QH ++ +GE +T+RVR M +A+LRNE+ WFD E N+ ++ RLA D Sbjct: 886 MGIVTVVANFLQHFYFGIMGEKMTERVRRMMFSAMLRNEVGWFDDEENSPDTLSMRLAND 945 Query: 190 AQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKG 369 A VR+A +R+S+ +Q+S ++VA G +L WR + QK+++ G Sbjct: 946 ATFVRAAFSNRLSIFIQDSFAVIVALLIGLLLGWRLALVALATLPILTLSAIAQKLWLAG 1005 Query: 370 FSGDLEGAHAKAT 408 FS ++ H KA+ Sbjct: 1006 FSKGIQEMHRKAS 1018
>MDR6_ARATH (Q8LPT1) Multidrug resistance protein 6 (P-glycoprotein 6)| Length = 1407 Score = 96.7 bits (239), Expect = 1e-20 Identities = 46/133 (34%), Positives = 77/133 (57%) Frame = +1 Query: 10 MSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALD 189 M ++ N +QH ++ +GE +T+RVR M +A+LRNE+ W+D E N+ ++ RLA D Sbjct: 885 MGIVTVVANFLQHFYFGIMGEKMTERVRRMMFSAMLRNEVGWYDEEENSPDTLSMRLAND 944 Query: 190 AQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKG 369 A VR+A +R+S+ +Q+S ++VA G +L WR + QK+++ G Sbjct: 945 ATFVRAAFSNRLSIFIQDSFAVIVAILIGLLLGWRLALVALATLPVLTLSAIAQKLWLAG 1004 Query: 370 FSGDLEGAHAKAT 408 FS ++ H KA+ Sbjct: 1005 FSKGIQEMHRKAS 1017
>MDR19_ARATH (Q9LSJ6) Putative multidrug resistance protein 19 (P-glycoprotein 17)| Length = 1240 Score = 92.0 bits (227), Expect = 3e-19 Identities = 43/97 (44%), Positives = 67/97 (69%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G++ + L N QH + +GE LTKR+RE+ML+ +L E+ WFD++ N+S I +RLA Sbjct: 720 VGLAIFSFLVNISQHYGFAYMGEYLTKRIREQMLSKILTFEVNWFDIDDNSSGAICSRLA 779 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 DA VRS +GDR+S++VQ + +++AC G V+ WR Sbjct: 780 KDANVVRSMVGDRMSLLVQTISAVIIACIIGLVIAWR 816 Score = 52.4 bits (124), Expect = 3e-07 Identities = 20/80 (25%), Positives = 44/80 (55%) Frame = +1 Query: 55 WDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 W GE R+REK L AVLR ++ +FD+ +++ + ++ D+ ++ + +++ Sbjct: 102 WTRTGERQAARMREKYLRAVLRQDVGYFDLHVTSTSDVITSISSDSLVIQDFLSEKLPNF 161 Query: 235 VQNSALMLVACTAGFVLQWR 294 + N++ + + F+L WR Sbjct: 162 LMNASAFVASYIVSFILMWR 181
>MDR13_ARATH (Q9LHD1) Multidrug resistance protein 13 (P-glycoprotein 15)| Length = 1240 Score = 90.1 bits (222), Expect = 1e-18 Identities = 43/97 (44%), Positives = 65/97 (67%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G++ + L N QH + +GE LTKR+RE+ML+ VL E+ WFD + N+S I +RLA Sbjct: 720 VGLAVLSFLINISQHYNFAYMGEYLTKRIRERMLSKVLTFEVGWFDRDENSSGAICSRLA 779 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 DA VRS +GDR++++VQ + + +A T G V+ WR Sbjct: 780 KDANVVRSLVGDRMALVVQTVSAVTIAFTMGLVIAWR 816 Score = 52.8 bits (125), Expect = 2e-07 Identities = 21/80 (26%), Positives = 46/80 (57%) Frame = +1 Query: 55 WDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 W GE T R+REK L AVLR ++ +FD+ +++ + ++ D+ ++ + +++ Sbjct: 102 WTRTGERQTARMREKYLRAVLRQDVGYFDLHVTSTSDVITSVSSDSFVIQDVLSEKLPNF 161 Query: 235 VQNSALMLVACTAGFVLQWR 294 + +++ + + GF+L WR Sbjct: 162 LMSASTFVGSYIVGFILLWR 181
>MDR20_ARATH (Q9LSJ5) Putative multidrug resistance protein 20 (P-glycoprotein| 18) Length = 1225 Score = 88.2 bits (217), Expect = 4e-18 Identities = 42/97 (43%), Positives = 62/97 (63%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G++ L N QH + +GE LTKR+RE+ML +L E+ WFD + N+S I +RLA Sbjct: 705 VGLALFTFLSNISQHYGFAYMGEYLTKRIRERMLGKILTFEVNWFDKDENSSGAICSRLA 764 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 DA VRS +GDR+S++VQ + + + C G V+ WR Sbjct: 765 KDANMVRSLVGDRMSLLVQTISAVSITCAIGLVISWR 801 Score = 53.1 bits (126), Expect = 2e-07 Identities = 22/98 (22%), Positives = 54/98 (55%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 L+ ++ A+ + ++ W GE ++REK L AVLR ++ +FD+ +++ + + Sbjct: 72 LVYVACASWVICFIEGYCWTRTGERQAAKMREKYLKAVLRQDVGYFDLHVTSTSDVITSV 131 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 + D+ ++ + +++ + N++ + + GF+L WR Sbjct: 132 SSDSLVIQDFLSEKLPNFLMNTSAFVASYIVGFLLLWR 169
>MDR10_ARATH (Q9SGY1) Multidrug resistance protein 10 (P-glycoprotein 10)| Length = 1316 Score = 87.8 bits (216), Expect = 6e-18 Identities = 47/147 (31%), Positives = 78/147 (53%), Gaps = 16/147 (10%) Frame = +1 Query: 13 SSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 S ++ +T++H + +GE LT RVR+KM +A+LRNE+ WFD N S+ +A+RL DA Sbjct: 776 SVITVIVHTIEHTTFGIMGERLTLRVRQKMFSAILRNEIGWFDKVDNTSSMLASRLESDA 835 Query: 193 QNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTV--------- 345 +R+ + DR +++++N L++ A F+L WR + Sbjct: 836 TLLRTIVVDRSTILLENLGLVVTAFIISFILNWRLTLVVLATYPLIISGHISEVKRSFLR 895 Query: 346 -------LQKMFMKGFSGDLEGAHAKA 405 QK+FM+G+ G+L A+ KA Sbjct: 896 FYILFFGRQKIFMQGYGGNLSKAYLKA 922
>MDR18_ARATH (Q9LSJ8) Multidrug resistance protein 18 (P-glycoprotein 16)| Length = 1228 Score = 87.4 bits (215), Expect = 7e-18 Identities = 45/123 (36%), Positives = 70/123 (56%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G++ + Q + +GE LTKR+RE+ML+ +L E+ WFD E N+S I +RLA Sbjct: 707 GLALFTFFTSISQQYSFSYMGEYLTKRIREQMLSKILTFEVNWFDEEENSSGAICSRLAK 766 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 DA VRS +G+R+S++VQ + ++VACT G V+ WR +Q++ +K Sbjct: 767 DANVVRSLVGERMSLLVQTISTVMVACTIGLVIAWRFTIVMISVQPVIIVCYYIQRVLLK 826 Query: 367 GFS 375 S Sbjct: 827 NMS 829 Score = 51.2 bits (121), Expect = 6e-07 Identities = 21/80 (26%), Positives = 46/80 (57%) Frame = +1 Query: 55 WDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 W GE ++RE+ L AVLR ++ +FD+ +++ I ++ D+ ++ + +++ I Sbjct: 89 WTRTGERQAAKMRERYLRAVLRQDVGYFDLHVTSTSDIITSVSSDSLVIQDFLSEKLPNI 148 Query: 235 VQNSALMLVACTAGFVLQWR 294 + N++ + + GF+L WR Sbjct: 149 LMNASAFVGSYIVGFMLLWR 168
>MDR21_ARATH (Q9LSJ2) Putative multidrug resistance protein 21 (P-glycoprotein 22)| Length = 1262 Score = 85.9 bits (211), Expect = 2e-17 Identities = 39/97 (40%), Positives = 64/97 (65%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G++ L + +Q + +GE LTKR+RE +L+ +L E++WFD + N+S I +RLA Sbjct: 742 VGLAVLCFLISIIQQYSFAYMGEYLTKRIRENILSKLLTFEVSWFDEDENSSGSICSRLA 801 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 DA VRS +G+R+S++VQ + + VACT G + W+ Sbjct: 802 KDANVVRSLVGERVSLLVQTISAVSVACTLGLAISWK 838 Score = 55.8 bits (133), Expect = 2e-08 Identities = 23/98 (23%), Positives = 54/98 (55%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 L+ ++ A+L+ V+ W GE R+REK L AVLR ++ +FD+ +++ + + Sbjct: 104 LLYVAGASLVICFVEGYCWTRTGERQASRMREKYLRAVLRQDVGYFDLHVTSTSDVITSV 163 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 + D ++ + +++ + +++ + + GF++ WR Sbjct: 164 SSDTLVIQDVLSEKLPNFLMSASAFVASYIVGFIMLWR 201
>MDR17_ARATH (Q9M1Q9) Multidrug resistance protein 17 (P-glycoprotein 21)| Length = 1292 Score = 70.1 bits (170), Expect = 1e-12 Identities = 41/131 (31%), Positives = 60/131 (45%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 L+G++S + Q +F+ G L +R+R V+R E+ WFD N+S I ARL Sbjct: 778 LLGVASMVVF--PAQTIFFSIAGCKLVQRIRSMCFEKVVRMEVGWFDETENSSGAIGARL 835 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMF 360 + DA VR +GD ++ VQN A + FV W+ + F Sbjct: 836 SADAATVRGLVGDALAQTVQNLASVTAGLVIAFVASWQLAFIVLAMLPLIGLNGYIYMKF 895 Query: 361 MKGFSGDLEGA 393 M GFS D + A Sbjct: 896 MVGFSADAKEA 906 Score = 42.0 bits (97), Expect = 3e-04 Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 4/98 (4%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G AALL Q W GE R+R L +LR ++A+FD+E N + + R++ Sbjct: 133 LGTLVAALL----QVSGWMISGERQAGRIRSLYLQTILRQDIAFFDVETN-TGEVVGRMS 187 Query: 184 LDAQNVRSAIGDRISVIVQNSALML----VACTAGFVL 285 D ++ A+G+++ +Q + + +A T G++L Sbjct: 188 GDTVLIQDAMGEKVGKAIQLVSTFIGGFVIAFTEGWLL 225
>MDR22_ARATH (Q9LHK4) Putative multidrug resistance protein 22 (P-glycoprotein 8)| Length = 1241 Score = 69.3 bits (168), Expect = 2e-12 Identities = 33/97 (34%), Positives = 58/97 (59%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 I ++ ++ N +QH + +GE L +R+R KML + E AWFD+E N ++ I +RL Sbjct: 724 ISLTFLSITLNLLQHYSFAKMGERLMQRLRLKMLEKIFTFEPAWFDVEENFTSEICSRLN 783 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 + V+S + DRIS++VQ + + +A G ++ W+ Sbjct: 784 NEVSIVKSLVADRISLLVQTISGVTIAMIIGLLISWK 820 Score = 37.7 bits (86), Expect = 0.007 Identities = 16/80 (20%), Positives = 37/80 (46%) Frame = +1 Query: 55 WDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 W E ++R L AVLR E+++FD + + S I ++ D ++ + +++ + Sbjct: 102 WSKTSERQVMKIRRTYLEAVLRQEVSFFDSDISTS-EIIHTISTDTSLIQQLLSEKVPIF 160 Query: 235 VQNSALMLVACTAGFVLQWR 294 + + ++ + WR Sbjct: 161 LMHISVFITGLVFSAYFSWR 180
>MDR4_ARATH (O80725) Multidrug resistance protein 4 (P-glycoprotein 4)| Length = 1286 Score = 69.3 bits (168), Expect = 2e-12 Identities = 38/130 (29%), Positives = 60/130 (46%) Frame = +1 Query: 19 AALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQN 198 A+++ Q F+ G L +R+R V+ E+ WFD N+S I ARL+ DA Sbjct: 772 ASIIAYPAQTFFFAIAGCKLVQRIRSMCFEKVVHMEVGWFDEPENSSGTIGARLSADAAT 831 Query: 199 VRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGFSG 378 +R +GD ++ VQN + +L F+ W+ L FMKGFS Sbjct: 832 IRGLVGDSLAQTVQNLSSILAGLIIAFLACWQLAFVVLAMLPLIALNGFLYMKFMKGFSA 891 Query: 379 DLEGAHAKAT 408 D + + +A+ Sbjct: 892 DAKKMYGEAS 901 Score = 44.3 bits (103), Expect = 7e-05 Identities = 27/96 (28%), Positives = 47/96 (48%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 IG +AA L Q W GE R+R L +LR ++A+FD++ N + + R++ Sbjct: 114 IGTFAAAFL----QLSGWMISGERQAARIRSLYLKTILRQDIAFFDIDTN-TGEVVGRMS 168 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQW 291 D ++ A+G+++ +Q A + FV W Sbjct: 169 GDTVLIQDAMGEKVGKAIQLLATFVGGFVIAFVRGW 204
>MDR8_ARATH (Q9FWX7) Multidrug resistance protein 8 (P-glycoprotein 11)| Length = 1278 Score = 68.6 bits (166), Expect = 3e-12 Identities = 37/135 (27%), Positives = 60/135 (44%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 + + +L+ + Q + G L +R+R + E+AWFD N+S + ARL+ Sbjct: 757 VALGVTSLIVSPTQMYLFAVAGGKLIRRIRSMCFEKAVHMEVAWFDEPQNSSGTMGARLS 816 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFM 363 DA +R+ +GD +S+ VQN A F W +Q FM Sbjct: 817 ADATLIRALVGDALSLAVQNVASAASGLIIAFTASWELALIILVMLPLIGINGFVQVKFM 876 Query: 364 KGFSGDLEGAHAKAT 408 KGFS D + + +A+ Sbjct: 877 KGFSADAKSKYEEAS 891 Score = 43.5 bits (101), Expect = 1e-04 Identities = 24/96 (25%), Positives = 45/96 (46%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G AA L Q W GE R+R L +LR ++ +FD+E N + + R++ Sbjct: 111 LGTLGAAFL----QVACWMITGERQAARIRSTYLKTILRQDIGFFDVETN-TGEVVGRMS 165 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQW 291 D ++ A+G+++ +Q + + F+ W Sbjct: 166 GDTVLIQDAMGEKVGKFIQLVSTFVGGFVLAFIKGW 201
>MDR5_ARATH (Q9SYI3) Putative multidrug resistance protein 5 (P-glycoprotein 5)| Length = 1230 Score = 68.6 bits (166), Expect = 3e-12 Identities = 39/136 (28%), Positives = 66/136 (48%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 L+G++ A +++ T +LF G L +R+R V+ E+ WFD N+S + ARL Sbjct: 711 LLGVA-AVIVYPTTNYLF-AIAGGRLIRRIRSMCFEKVVHMEVGWFDEPGNSSGAMGARL 768 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMF 360 + DA +R+ +GD + + V+N A ++ F W +Q F Sbjct: 769 SADAALIRTLVGDSLCLSVKNVASLVTGLIIAFTASWEVAIIILVIIPFIGINGYIQIKF 828 Query: 361 MKGFSGDLEGAHAKAT 408 MKGFS D + + +A+ Sbjct: 829 MKGFSADAKAKYEEAS 844 Score = 38.9 bits (89), Expect = 0.003 Identities = 22/97 (22%), Positives = 44/97 (45%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 L+ + AL +Q W GE R+R L +LR ++ +FD+E + + R+ Sbjct: 78 LVYLGLGALGAAFLQVACWMITGERQAARIRSLYLKTILRQDIGFFDVEM-TTGEVVGRM 136 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQW 291 + D + A+G+++ +Q + + F+ W Sbjct: 137 SGDTVLILDAMGEKVGKFIQLISTFVGGFVIAFLRGW 173
>MDR16_ARATH (Q9FWX8) Multidrug resistance protein 16 (P-glycoprotein 12)| Length = 1229 Score = 67.4 bits (163), Expect = 8e-12 Identities = 36/135 (26%), Positives = 61/135 (45%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 + + +L+ + Q + G L +R++ + E++WFD N+S + ARL+ Sbjct: 708 VALGVTSLIVSPSQMYLFAVAGGKLIRRIQSMCFEKAVHMEVSWFDEPENSSGTMGARLS 767 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFM 363 DA +R+ +GD +S+ VQN+A F W LQ FM Sbjct: 768 TDAALIRALVGDALSLAVQNAASAASGLIIAFTASWELALIILVMLPLIGINGFLQVKFM 827 Query: 364 KGFSGDLEGAHAKAT 408 KGFS D + + +A+ Sbjct: 828 KGFSADAKSKYEEAS 842 Score = 43.1 bits (100), Expect = 2e-04 Identities = 23/96 (23%), Positives = 45/96 (46%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G AA L Q W GE ++R L +LR ++ +FD+E N + + R++ Sbjct: 54 LGRLGAAFL----QVACWMITGERQAAKIRSNYLKTILRQDIGFFDVETN-TGEVVGRMS 108 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQW 291 D +++ A+G+++ +Q + + F W Sbjct: 109 GDTVHIQDAMGEKVGKFIQLVSTFVGGFALAFAKGW 144
>MDR7_ARATH (Q9FHF1) Multidrug resistance protein 7 (P-glycoprotein 7)| Length = 1248 Score = 66.2 bits (160), Expect = 2e-11 Identities = 37/135 (27%), Positives = 60/135 (44%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 + + L+ +Q+ + G L KR+R VL +++WFD N+S I ARL+ Sbjct: 730 VALGLTDLIVIPLQNYLFAIAGAKLIKRIRSLSFDRVLHQDISWFDDTKNSSGVIGARLS 789 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFM 363 DA V+S +GD + +I+QN A ++ A F W Q F+ Sbjct: 790 TDASTVKSIVGDVLGLIMQNMATIIGAFIIAFTANWLLALMALLVAPVMFFQGYYQIKFI 849 Query: 364 KGFSGDLEGAHAKAT 408 GF G + +A+ Sbjct: 850 TGFGAKARGKYEEAS 864 Score = 39.3 bits (90), Expect = 0.002 Identities = 18/77 (23%), Positives = 39/77 (50%) Frame = +1 Query: 55 WDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 W GE + R+R L +LR ++ +FD E N + + R++ D ++ ++G+++ Sbjct: 100 WMVTGERQSTRIRRLYLKTILRQDIGFFDTETN-TGEVIGRMSGDTILIQDSMGEKVGKF 158 Query: 235 VQNSALMLVACTAGFVL 285 Q + + T F++ Sbjct: 159 TQLVSSFVGGFTVAFIV 175
>MDR49_DROME (Q00449) Multidrug resistance protein homolog 49 (EC 3.6.3.44)| (P-glycoprotein 49) Length = 1302 Score = 64.7 bits (156), Expect = 5e-11 Identities = 31/97 (31%), Positives = 54/97 (55%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G+ A L N +Q + T G +T R+R++ ++ ++A+FD E N+ + +RLA Sbjct: 783 VGIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLA 842 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 D NV+ A G R+ ++Q A ++V GFV W+ Sbjct: 843 SDCSNVQGATGARVGTMLQAVATLVVGMVVGFVFSWQ 879 Score = 45.1 bits (105), Expect = 4e-05 Identities = 25/98 (25%), Positives = 52/98 (53%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 L+G S A L T+ + + N R+R+ L A+LR ++AW+D ++ ++ A+++ Sbjct: 123 LVG-SVAMFLLITLAIDLANRIALNQIDRIRKLFLEAMLRQDIAWYD--TSSGSNFASKM 179 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 D ++ IG++I ++V ++ + FV W+ Sbjct: 180 TEDLDKLKEGIGEKIVIVVFLIMTFVIGIVSAFVYGWK 217
>MDR1_HUMAN (P08183) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| 1) (CD243 antigen) Length = 1280 Score = 63.5 bits (153), Expect = 1e-10 Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 4/127 (3%) Frame = +1 Query: 40 VQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGD 219 +Q + GE LTKR+R + ++LR +++WFD N + + RLA DA V+ AIG Sbjct: 772 LQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGS 831 Query: 220 RISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGFS----GDLE 387 R++VI QN A + F+ W+ V++ + G + +LE Sbjct: 832 RLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELE 891 Query: 388 GAHAKAT 408 GA AT Sbjct: 892 GAGKIAT 898 Score = 50.1 bits (118), Expect = 1e-06 Identities = 29/133 (21%), Positives = 52/133 (39%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ + L+ +Q FW ++R++ A++R E+ WFD+ + + RL Sbjct: 120 GIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWFDV--HDVGELNTRLTD 177 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 D + IGD+I + Q+ A GF W+ + + Sbjct: 178 DVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILS 237 Query: 367 GFSGDLEGAHAKA 405 F+ A+AKA Sbjct: 238 SFTDKELLAYAKA 250
>MDR3_ARATH (Q9SYI2) Putative multidrug resistance protein 3 (P-glycoprotein 3)| Length = 1229 Score = 62.8 bits (151), Expect = 2e-10 Identities = 34/130 (26%), Positives = 61/130 (46%) Frame = +1 Query: 19 AALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQN 198 A+L+ + + G L +R+R V+ E+ WFD N+S I +RL+ DA Sbjct: 714 ASLIVYPMHTYLFAVAGGRLIQRIRVMCFEKVVHMEVGWFDDPENSSGTIGSRLSADAAL 773 Query: 199 VRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGFSG 378 +++ +GD +S+ V+N+A + F W+ LQ F+KGF+ Sbjct: 774 IKTLVGDSLSLSVKNAAAAVSGLIIAFTASWKLAVIILVMIPLIGINGYLQIKFIKGFTA 833 Query: 379 DLEGAHAKAT 408 D + + +A+ Sbjct: 834 DAKAKYEEAS 843 Score = 41.6 bits (96), Expect = 5e-04 Identities = 25/96 (26%), Positives = 44/96 (45%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G AA L Q W GE R+R L +LR ++ +FD+E ++ + R++ Sbjct: 78 LGTLGAAFL----QVACWMITGERQAARIRSLYLKTILRQDIGFFDVE-TSTGEVVGRMS 132 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQW 291 D + A+G+++ +Q A + FV W Sbjct: 133 GDTVLILEAMGEKVGKFIQLIATFVGGFVLAFVKGW 168
>MDR2_RAT (Q08201) Multidrug resistance protein 2 (EC 3.6.3.44)| (P-glycoprotein 2) (P-glycoprotein 3) Length = 1278 Score = 62.4 bits (150), Expect = 2e-10 Identities = 34/133 (25%), Positives = 54/133 (40%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ LL +Q FW +++R+K A+LR EM WFD++ + + RL Sbjct: 119 GLGGGVLLAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEMGWFDIK--GTTELNTRLTD 176 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 D + IGD++ + Q A GF+ W+ T + + Sbjct: 177 DISKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAITAILGLSTAVWAKILS 236 Query: 367 GFSGDLEGAHAKA 405 FS A+AKA Sbjct: 237 TFSDKELAAYAKA 249 Score = 61.6 bits (148), Expect = 4e-10 Identities = 30/85 (35%), Positives = 48/85 (56%) Frame = +1 Query: 40 VQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGD 219 +Q + GE LT R+R A+LR +M+WFD N++ ++ RLA DA V+ A G Sbjct: 770 LQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGT 829 Query: 220 RISVIVQNSALMLVACTAGFVLQWR 294 R+++I QN+A + F+ W+ Sbjct: 830 RLALIAQNTANLGTGIIISFIYGWQ 854
>MDR2_MOUSE (P21440) Multidrug resistance protein 2 (EC 3.6.3.44)| (P-glycoprotein 2) Length = 1276 Score = 62.0 bits (149), Expect = 3e-10 Identities = 34/133 (25%), Positives = 54/133 (40%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ L+ +Q FW K++R+K A+LR EM WFD++ + + RL Sbjct: 119 GLGGGVLVAAYIQVSFWTLAAGRQIKKIRQKFFHAILRQEMGWFDIK--GTTELNTRLTD 176 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 D + IGD++ + Q A GF+ W+ T + + Sbjct: 177 DVSKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLVIMAISPILGLSTAVWAKILS 236 Query: 367 GFSGDLEGAHAKA 405 FS A+AKA Sbjct: 237 TFSDKELAAYAKA 249 Score = 60.8 bits (146), Expect = 7e-10 Identities = 30/97 (30%), Positives = 52/97 (53%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G+ + +Q + GE LT R+R A+LR +M+WFD N++ ++ RLA Sbjct: 756 LGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLA 815 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 DA V+ A G ++++I QN+A + F+ W+ Sbjct: 816 TDAAQVQGATGTKLALIAQNTANLGTGIIISFIYGWQ 852
>MDR3_HUMAN (P21439) Multidrug resistance protein 3 (EC 3.6.3.44) (P-glycoprotein| 3) Length = 1279 Score = 61.6 bits (148), Expect = 4e-10 Identities = 30/85 (35%), Positives = 48/85 (56%) Frame = +1 Query: 40 VQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGD 219 +Q + GE LT+R+R A+LR +M+WFD N++ ++ RLA DA V+ A G Sbjct: 771 LQGFTFGKAGEILTRRLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGT 830 Query: 220 RISVIVQNSALMLVACTAGFVLQWR 294 R+++I QN A + F+ W+ Sbjct: 831 RLALIAQNIANLGTGIIISFIYGWQ 855 Score = 59.3 bits (142), Expect = 2e-09 Identities = 32/133 (24%), Positives = 54/133 (40%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ + L+ +Q FW +++R+K A+LR E+ WFD+ N + + RL Sbjct: 122 GLGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEIGWFDI--NDTTELNTRLTD 179 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 D + IGD++ + Q A GF+ W+ + + Sbjct: 180 DISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILS 239 Query: 367 GFSGDLEGAHAKA 405 FS A+AKA Sbjct: 240 AFSDKELAAYAKA 252
>MDR1_RAT (P43245) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| 1) (CD243 antigen) Length = 1277 Score = 61.2 bits (147), Expect = 6e-10 Identities = 32/83 (38%), Positives = 49/83 (59%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 ++GM S F Q + GE LTKR+R + ++LR +++WFD N + + RL Sbjct: 759 VMGMISFVTYF--FQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDHKNTTGSLTTRL 816 Query: 181 ALDAQNVRSAIGDRISVIVQNSA 249 A DA NV+ A+G R++V+ QN A Sbjct: 817 ASDASNVKGAMGSRLAVVTQNVA 839 Score = 50.1 bits (118), Expect = 1e-06 Identities = 27/133 (20%), Positives = 52/133 (39%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ + L+ +Q W ++R+K A++ E+ WFD+ N + + RL Sbjct: 119 GIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFDV--NDAGELNTRLTD 176 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 D + IGD++ + Q+ GF+ W+ + + + Sbjct: 177 DVSKINDGIGDKLGMFFQSITTFSAGFIIGFISGWKLTLVILAVSPLIGLSSAMWAKVLT 236 Query: 367 GFSGDLEGAHAKA 405 F+ A+AKA Sbjct: 237 SFTNKELQAYAKA 249
>MDR1_MOUSE (P06795) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| 1) (CD243 antigen) Length = 1276 Score = 60.8 bits (146), Expect = 7e-10 Identities = 29/76 (38%), Positives = 46/76 (60%) Frame = +1 Query: 67 GENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIVQNS 246 GE LTKRVR + ++LR +++WFD N++ + RLA DA +V+ A+G R++V+ QN Sbjct: 779 GEILTKRVRYMVFKSMLRQDISWFDDHKNSTGSLTTRLASDASSVKGAMGARLAVVTQNV 838 Query: 247 ALMLVACTAGFVLQWR 294 A + V W+ Sbjct: 839 ANLGTGVILSLVYGWQ 854 Score = 50.8 bits (120), Expect = 7e-07 Identities = 29/133 (21%), Positives = 52/133 (39%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ + L+ +Q W ++R+K A++ E+ WFD+ + + RL Sbjct: 119 GIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFDV--HDVGELNTRLTD 176 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 D + IGD+I + Q+ L GF+ W+ + L + Sbjct: 177 DVSKINDGIGDKIGMFFQSITTFLAGFIIGFISGWKLTLVILAVSPLIGLSSALWAKVLT 236 Query: 367 GFSGDLEGAHAKA 405 F+ A+AKA Sbjct: 237 SFTNKELQAYAKA 249
>MDR3_CRIGR (P23174) Multidrug resistance protein 3 (EC 3.6.3.44) (P-glycoprotein| 3) Length = 1281 Score = 59.3 bits (142), Expect = 2e-09 Identities = 30/97 (30%), Positives = 51/97 (52%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G+ + +Q + GE LT R+R A+LR +M+WFD N++ ++ RLA Sbjct: 761 LGLGVLSFFTFFLQGFTFGKAGEILTTRLRSMAFKAMLRQDMSWFDDYKNSTGALSTRLA 820 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 D V+ A G R+++I QN+A + F+ W+ Sbjct: 821 TDRAQVQGATGTRLALIAQNTANLGTGIIISFIYGWQ 857 Score = 57.8 bits (138), Expect = 6e-09 Identities = 32/133 (24%), Positives = 52/133 (39%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ L+ +Q FW K++R+ A+LR EM WFD++ + + RL Sbjct: 122 GLGGGVLVAAYIQVSFWTLAAGRQIKKIRQNFFHAILRQEMGWFDIK--GTTELNTRLTD 179 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 D + IGD++ + Q A GF+ W+ + + Sbjct: 180 DISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILS 239 Query: 367 GFSGDLEGAHAKA 405 FS A+AKA Sbjct: 240 TFSDKELAAYAKA 252
>MDR3_MOUSE (P21447) Multidrug resistance protein 3 (EC 3.6.3.44) (P-glycoprotein| 3) (MDR1A) Length = 1276 Score = 58.5 bits (140), Expect = 4e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 4/140 (2%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 ++G+ S F +Q + GE LTKR+R + ++LR +++WFD N + + RL Sbjct: 757 ILGIISFITFF--LQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRL 814 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMF 360 A DA V+ A G R++VI QN A + + W+ V++ Sbjct: 815 ANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKM 874 Query: 361 MKGFS----GDLEGAHAKAT 408 + G + +LEG+ AT Sbjct: 875 LSGQALKDKKELEGSGKIAT 894 Score = 48.1 bits (113), Expect = 5e-06 Identities = 29/133 (21%), Positives = 50/133 (37%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ + L+ +Q FW ++R+K A++ E+ WFD+ + + RL Sbjct: 116 GIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDV--HDVGELNTRLTD 173 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 D + IGD+I + Q A GF W+ + + Sbjct: 174 DVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILS 233 Query: 367 GFSGDLEGAHAKA 405 F+ A+AKA Sbjct: 234 SFTDKELHAYAKA 246
>MDR1_CRIGR (P21448) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| 1) (CD243 antigen) Length = 1276 Score = 58.2 bits (139), Expect = 5e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 4/140 (2%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 ++G+ S F +Q + GE LTKR+R + ++LR +++WFD N + + RL Sbjct: 758 ILGVISFITFF--LQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDNPKNTTGALTTRL 815 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMF 360 A DA V+ A G R++VI QN A + + W+ V++ Sbjct: 816 ANDAGQVKGATGARLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKM 875 Query: 361 MKGFS----GDLEGAHAKAT 408 + G + +LEG+ AT Sbjct: 876 LSGQALKDKKELEGSGKIAT 895 Score = 48.1 bits (113), Expect = 5e-06 Identities = 29/133 (21%), Positives = 50/133 (37%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ + L+ +Q FW ++R+K A++ E+ WFD+ + + RL Sbjct: 117 GIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDV--HDVGELNTRLTD 174 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 D + IGD+I + Q A GF W+ + + Sbjct: 175 DVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILS 234 Query: 367 GFSGDLEGAHAKA 405 F+ A+AKA Sbjct: 235 SFTDKELQAYAKA 247
>MDR2_CRIGR (P21449) Multidrug resistance protein 2 (EC 3.6.3.44) (P-glycoprotein| 2) Length = 1276 Score = 57.0 bits (136), Expect = 1e-08 Identities = 28/76 (36%), Positives = 44/76 (57%) Frame = +1 Query: 67 GENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIVQNS 246 GE LTKR+R + ++LR +++WFD N++ + RLA DA NV+ A+ R++ I QN Sbjct: 779 GEILTKRLRYMVFKSMLRQDISWFDDHRNSTGALTTRLASDAANVKGAMSSRLAGITQNV 838 Query: 247 ALMLVACTAGFVLQWR 294 A + V W+ Sbjct: 839 ANLGTGIIISLVYGWQ 854 Score = 56.2 bits (134), Expect = 2e-08 Identities = 31/133 (23%), Positives = 55/133 (41%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ + L+ +Q FW ++R+K A++ E+ WFD+ + + RL Sbjct: 119 GIGAGVLIVAYIQVSFWCLAAGRQINKIRQKFFHAIMNQEIGWFDV--HDIGELNTRLTD 176 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMK 366 D + IGD+I + Q+ A L A GF+ W+ + + + Sbjct: 177 DVSKINDGIGDKIGMFFQSIATFLAAFIVGFISGWKLTLVILAVSPLIGLSSAMWAKVLT 236 Query: 367 GFSGDLEGAHAKA 405 F+ A+AKA Sbjct: 237 SFTNKELQAYAKA 249
>ABCBB_HUMAN (O95342) Bile salt export pump (ATP-binding cassette sub-family B| member 11) Length = 1321 Score = 57.0 bits (136), Expect = 1e-08 Identities = 32/97 (32%), Positives = 49/97 (50%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 + M +L +Q + GE LTKR+R+ A+L ++AWFD N+ + RLA Sbjct: 803 VAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLA 862 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 DA V+ A G +I +IV + + VA F W+ Sbjct: 863 TDASQVQGAAGSQIGMIVNSFTNVTVAMIIAFSFSWK 899 Score = 45.8 bits (107), Expect = 2e-05 Identities = 22/96 (22%), Positives = 44/96 (45%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G++ A L+ +Q FW +++R+ ++R E+ WFD N+ + R + Sbjct: 147 GIAVAVLITGYIQICFWVIAAARQIQKMRKFYFRRIMRMEIGWFD--CNSVGELNTRFSD 204 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 D + AI D++++ +Q + GF W+ Sbjct: 205 DINKINDAIADQMALFIQRMTSTICGFLLGFFRGWK 240
>ABCBB_RABIT (Q9N0V3) Bile salt export pump (ATP-binding cassette sub-family B| member 11) (Sister of P-glycoprotein) Length = 1321 Score = 56.2 bits (134), Expect = 2e-08 Identities = 34/113 (30%), Positives = 52/113 (46%) Frame = +1 Query: 67 GENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIVQNS 246 GE LTKR+R+ A+L ++ WFD N+ + RLA DA V+ A G +I ++V + Sbjct: 824 GELLTKRLRKFGFRAMLGQDIGWFDDLRNSPGALTTRLATDASQVQGATGSQIGMMVNSF 883 Query: 247 ALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGFSGDLEGAHAKA 405 + VA F+ W+ LQ + GF+ + A KA Sbjct: 884 TNVTVAMIIAFLFSWKLTLGIVCFFPFLALSGALQTKMLTGFASRDKQALEKA 936 Score = 37.0 bits (84), Expect = 0.011 Identities = 17/96 (17%), Positives = 40/96 (41%) Frame = +1 Query: 7 GMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLAL 186 G+ A L +Q FW + +++R+ ++R + W D N+ + ++ Sbjct: 147 GIGIAVLTTGYIQICFWGIAAAHQIQKMRKSYFRKIMRMGIGWVD--CNSVGKLNTPFSV 204 Query: 187 DAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 D + + D++++ +Q + GF W+ Sbjct: 205 DFNKINDSSADQLAIFIQGMTSPIFGFLVGFSQWWK 240
>ABCBB_MOUSE (Q9QY30) Bile salt export pump (ATP-binding cassette sub-family B| member 11) (Sister of P-glycoprotein) Length = 1321 Score = 56.2 bits (134), Expect = 2e-08 Identities = 30/103 (29%), Positives = 48/103 (46%) Frame = +1 Query: 67 GENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIVQNS 246 GE LTKR+R+ A+LR ++ WFD N + RLA DA V+ A G ++ ++V + Sbjct: 824 GELLTKRLRKFGFKAMLRQDIGWFDDLKNNPGVLTTRLATDASQVQGATGSQVGMMVNSF 883 Query: 247 ALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGFS 375 + VA F+ W+ +Q + GF+ Sbjct: 884 TNIFVAVLIAFLFNWKLSLVISVFFPFLALSGAVQTKMLTGFA 926
>ABCBB_RAT (O70127) Bile salt export pump (ATP-binding cassette sub-family B| member 11) (Sister of P-glycoprotein) Length = 1321 Score = 53.5 bits (127), Expect = 1e-07 Identities = 31/113 (27%), Positives = 50/113 (44%) Frame = +1 Query: 67 GENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIVQNS 246 GE LTKR+R+ A+L ++ WFD N + RLA DA V+ A G ++ ++V + Sbjct: 824 GELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGVLTTRLATDASQVQGATGSQVGMMVNSF 883 Query: 247 ALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGFSGDLEGAHAKA 405 ++ A F W+ +Q + GF+ + A KA Sbjct: 884 TNIIAALLIAFFFSWKLSLIITIFFPFLALSGAVQTKMLTGFASQDKQALEKA 936
>MDR1_CAEEL (P34712) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| A) Length = 1321 Score = 52.8 bits (125), Expect = 2e-07 Identities = 28/95 (29%), Positives = 47/95 (49%) Frame = +1 Query: 10 MSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALD 189 +++A + + + F E+LT+ +R K+ VL + +FD NAS I+ RLA D Sbjct: 803 LAAAQGICSFLMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQNASGKISTRLATD 862 Query: 190 AQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 N+R+AI R S ++ M+ F W+ Sbjct: 863 VPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGWQ 897 Score = 44.3 bits (103), Expect = 7e-05 Identities = 21/77 (27%), Positives = 39/77 (50%) Frame = +1 Query: 64 VGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIVQN 243 V E + R+R + + ++LR E++WFD N S +A +L + + V+ GD+I + Q Sbjct: 163 VAEQMNNRLRREFVKSILRQEISWFD--TNHSGTLATKLFDNLERVKEGTGDKIGMAFQY 220 Query: 244 SALMLVACTAGFVLQWR 294 + + F W+ Sbjct: 221 LSQFITGFIVAFTHSWQ 237
>MDR1_LEIEN (Q06034) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| 1) Length = 1280 Score = 52.0 bits (123), Expect = 3e-07 Identities = 25/117 (21%), Positives = 54/117 (46%) Frame = +1 Query: 40 VQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGD 219 + H F+ GE+LT ++R + ++R ++ +FD+ + +A L+ D + V G Sbjct: 776 ILHGFYGYAGEHLTTKIRVLLFRQIMRQDINFFDIPGRDAGTLAGMLSGDCEAVHQLWGP 835 Query: 220 RISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGFSGDLEG 390 I + VQ ++ GF+ QW+ ++ +++ + G++ EG Sbjct: 836 SIGLKVQTMCIIASGLVVGFIYQWKLALVALACMPLMIGCSLTRRLMINGYTKSREG 892 Score = 44.7 bits (104), Expect = 5e-05 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%) Frame = +1 Query: 22 ALLFNTVQHLF-WDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQN 198 A+L H+ W R+R AVLR ++ W D ++ + AR+ D + Sbjct: 124 AMLIACAGHVMCWTVAACRQVARIRLLFFRAVLRQDIGWHD--EHSPGALTARMTGDTRV 181 Query: 199 VRSAIGDRISVIVQNSALMLVACTAGFVLQW 291 +++ I D++S + N ++ ++ AGFV W Sbjct: 182 IQNGINDKLSQGIMNGSMGVIGYIAGFVFSW 212
>MDR9_ARATH (Q9M0M2) Multidrug resistance protein 9 (P-glycoprotein 9)| Length = 1323 Score = 51.6 bits (122), Expect = 4e-07 Identities = 35/150 (23%), Positives = 55/150 (36%), Gaps = 27/150 (18%) Frame = +1 Query: 40 VQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAH------------------ 165 V + F+ G L KR+R V+ E++WFD AN+ + Sbjct: 745 VPNYFFGIAGGKLIKRIRSMCFDKVVHQEISWFDDTANSRYYNFIYIINRRILYVLILIF 804 Query: 166 ---------IAARLALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXX 318 + + DA VRS +GD +++IVQN A + F W Sbjct: 805 ICVLLPPVRLERECSTDASTVRSLVGDALALIVQNIATVTTGLIIAFTANWILALIVLAL 864 Query: 319 XXXXXXXTVLQKMFMKGFSGDLEGAHAKAT 408 Q F+ GFS D + + +A+ Sbjct: 865 SPFIVIQGYAQTKFLTGFSADAKAMYEEAS 894 Score = 36.2 bits (82), Expect = 0.019 Identities = 19/77 (24%), Positives = 37/77 (48%) Frame = +1 Query: 55 WDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 W GE + +R L +LR ++ +FD E N + + R++ D ++ A+G+++ Sbjct: 98 WMVTGERQSATIRGLYLKTILRQDIGYFDTETN-TGEVIGRMSGDTILIQDAMGEKVGKF 156 Query: 235 VQNSALMLVACTAGFVL 285 Q +L GF + Sbjct: 157 TQ----LLCTFLGGFAI 169
>MDR65_DROME (Q00748) Multidrug resistance protein homolog 65 (EC 3.6.3.44)| (P-glycoprotein 65) Length = 1302 Score = 45.8 bits (107), Expect = 2e-05 Identities = 25/97 (25%), Positives = 51/97 (52%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 +G++ L +Q ++ G LT R+R A++ E+ WFD E N+ ++ARL+ Sbjct: 780 LGLAFLTGLVCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENNSVGALSARLS 839 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 +A +++ AIG +S ++Q + + + + W+ Sbjct: 840 GEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWK 876
>MDR3_CAEEL (P34713) Multidrug resistance protein 3 (EC 3.6.3.44)| (P-glycoprotein C) Length = 1268 Score = 41.6 bits (96), Expect = 5e-04 Identities = 20/78 (25%), Positives = 39/78 (50%) Frame = +1 Query: 61 TVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIVQ 240 T+ E +R+K L +VLR + WFD + +++ + ++ IGD++ V+V Sbjct: 122 TLCERRLHCIRKKYLKSVLRQDAKWFD--ETTIGGLTQKMSSGIEKIKDGIGDKVGVLVG 179 Query: 241 NSALMLVACTAGFVLQWR 294 A + + GF + W+ Sbjct: 180 GVATFISGVSIGFYMCWQ 197 Score = 39.7 bits (91), Expect = 0.002 Identities = 18/75 (24%), Positives = 38/75 (50%) Frame = +1 Query: 67 GENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIVQNS 246 GE ++ R+R + +++ + ++FD + + +RLA DA NV++AI R++ ++ Sbjct: 776 GETMSGRLRMDVFRNIMQQDASYFDDSRHNVGSLTSRLATDAPNVQAAIDQRLAEVLTGI 835 Query: 247 ALMLVACTAGFVLQW 291 + F W Sbjct: 836 VSLFCGVGVAFYYGW 850
>STE6_YEAST (P12866) Mating factor A secretion protein STE6 (Multiple drug| resistance protein homolog) (P-glycoprotein) Length = 1290 Score = 41.2 bits (95), Expect = 6e-04 Identities = 21/98 (21%), Positives = 47/98 (47%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 ++G+++A +FN + D E +R +++ + R M WF E N ++ I+A + Sbjct: 766 VLGVAAADGIFNFAKGFLLDCCSEYWVMDLRNEVMEKLTRKNMDWFSGENNKASEISALV 825 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 D +++RS + + +S + + + V W+ Sbjct: 826 LNDLRDLRSLVSEFLSAMTSFVTVSTIGLIWALVSGWK 863
>MDR_PLAFF (P13568) Multidrug resistance protein (EC 3.6.3.44) (Chloroquine| resistance protein) Length = 1419 Score = 38.9 bits (89), Expect = 0.003 Identities = 18/87 (20%), Positives = 44/87 (50%) Frame = +1 Query: 19 AALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQN 198 A + T+++ + + +GE + K ++ ++ +L EM++FD + N ++A + D Sbjct: 840 AMFISETLKNYYNNKIGEKVEKTMKRRLFENILYQEMSFFDQDKNTPGVLSAHINRDVHL 899 Query: 199 VRSAIGDRISVIVQNSALMLVACTAGF 279 +++ + + I + L LV+ F Sbjct: 900 LKTGLVNNIVIFSHFIMLFLVSMVMSF 926
>PMD1_SCHPO (P36619) Leptomycin B resistance protein pmd1| Length = 1362 Score = 37.7 bits (86), Expect = 0.007 Identities = 16/76 (21%), Positives = 36/76 (47%) Frame = +1 Query: 67 GENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIVQNS 246 GE + +R+R+ L A+L + +FD + I R+ D ++ +G+++ ++ Sbjct: 168 GERIARRIRQDYLHAILSQNIGYFD--RLGAGEITTRITTDTNFIQDGLGEKVGLVFFAI 225 Query: 247 ALMLVACTAGFVLQWR 294 A + F+ W+ Sbjct: 226 ATFVSGFVIAFIRHWK 241 Score = 27.3 bits (59), Expect = 8.9 Identities = 13/57 (22%), Positives = 25/57 (43%) Frame = +1 Query: 70 ENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIVQ 240 E + +R+R + +LR ++ +FD N I L+ Q++ G + Q Sbjct: 865 EAVLQRIRYHLFRTLLRQDVEFFDRSENTVGAITTSLSTKIQSLEGLSGPTLGTFFQ 921
>RPOB_VIBF1 (Q5E238) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1341 Score = 35.8 bits (81), Expect = 0.025 Identities = 20/62 (32%), Positives = 34/62 (54%) Frame = +1 Query: 49 LFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRIS 228 LF+D V E + + +++ LR E A FD+EAN ++ A + A+++R D I+ Sbjct: 223 LFFDKVFEVKDQTLMMELIPERLRGETATFDIEANGKVYVEAGRRITARHIRQLTKDDIT 282 Query: 229 VI 234 I Sbjct: 283 HI 284
>MDLB_BUCBP (Q89A96) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 578 Score = 35.8 bits (81), Expect = 0.025 Identities = 18/91 (19%), Positives = 44/91 (48%) Frame = +1 Query: 22 ALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNV 201 A + N Q++ ++ + + +++R ++++ L+ + FD +R+ D + + Sbjct: 76 AAILNYHQNIIFNKISLTVIQKLRYDVMSSTLQLPIKMFDQRP--IGQFISRITNDTETI 133 Query: 202 RSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 + I + QN L+L+ F+L+WR Sbjct: 134 KELYDTVIKSLFQNIILILITLITMFILEWR 164
>TAGB_DICDI (P54683) Prestalk-specific protein tagB precursor (EC 3.4.21.-)| Length = 1905 Score = 35.8 bits (81), Expect = 0.025 Identities = 28/127 (22%), Positives = 52/127 (40%) Frame = +1 Query: 28 LFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRS 207 LF V V E + R++ K+ A++ +M +F + N SA + L +D +RS Sbjct: 1133 LFTNVGSWISGIVNEKMVMRLQNKVFRALIAQDMGFF--QRNNSALLMNVLIVDTPMLRS 1190 Query: 208 AIGDRISVIVQNSALMLVACTAGFVLQWRXXXXXXXXXXXXXXXTVLQKMFMKGFSGDLE 387 A+ + I ++ + F + W+ T +Q F K + L Sbjct: 1191 ALTGILLSIATGVCKLVGSLVFIFTISWKLSLAFFAAVPILGLVTQIQSQFTKRLTRQLL 1250 Query: 388 GAHAKAT 408 ++KA+ Sbjct: 1251 FHNSKAS 1257
>RPOB_YERPS (Q66FQ2) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 32.7 bits (73), Expect = 0.21 Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 6/87 (6%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL F T Q L F V E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNFTTAQILDLFFEKVVFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKARRITA 271 Query: 193 QNVRSAIG---DRISVIVQNSALMLVA 264 +++R DRI V V+ A +VA Sbjct: 272 RHIRQLEKDGIDRIEVPVEYIAGKVVA 298
>RPOB_YERPE (Q8ZAP5) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 32.7 bits (73), Expect = 0.21 Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 6/87 (6%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL F T Q L F V E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNFTTAQILDLFFEKVVFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKARRITA 271 Query: 193 QNVRSAIG---DRISVIVQNSALMLVA 264 +++R DRI V V+ A +VA Sbjct: 272 RHIRQLEKDGIDRIEVPVEYIAGKVVA 298
>LMRA_LACLA (Q9CHL8) Multidrug resistance ABC transporter ATP-binding and| permease protein (EC 3.6.3.44) Length = 590 Score = 32.0 bits (71), Expect = 0.36 Identities = 24/97 (24%), Positives = 49/97 (50%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 IG ++ + + V +F ++V +NL RV +KM+ ++ +FD + +++RLA Sbjct: 83 IGSAAVSAIAAIVLGIFGESVVKNLRTRVWDKMIHLPVK----YFDEVK--TGEMSSRLA 136 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 D V++ I + I + L++ + +QWR Sbjct: 137 NDTTQVKNLIANSIPQAFTSILLLVGSIVFMLQMQWR 173
>ABCB8_HUMAN (Q9NUT2) ATP-binding cassette sub-family B member 8, mitochondrial| precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1) Length = 735 Score = 32.0 bits (71), Expect = 0.36 Identities = 15/49 (30%), Positives = 28/49 (57%) Frame = +1 Query: 64 VGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSA 210 VGE + +R + +++LR + +FD AN + + +RL D Q +S+ Sbjct: 219 VGERMAVDMRRALFSSLLRQNITFFD--ANKTGQLVSRLTTDVQEFKSS 265
>LMRA_LACLC (P97046) Multidrug resistance ABC transporter ATP-binding and| permease protein (EC 3.6.3.44) Length = 590 Score = 31.6 bits (70), Expect = 0.47 Identities = 24/97 (24%), Positives = 49/97 (50%) Frame = +1 Query: 4 IGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLA 183 IG ++ + + V +F ++V +NL RV +KM+ ++ +FD + +++RLA Sbjct: 83 IGSAAVSAIAAIVLGIFGESVVKNLRTRVWDKMIHLPVK----YFDEVK--TGEMSSRLA 136 Query: 184 LDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 D V++ I + I + L++ + +QWR Sbjct: 137 NDTTQVKNLIANSIPQAFTSILLLVGSIIFMLQMQWR 173
>RPOB_HAEIN (P43738) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1343 Score = 31.6 bits (70), Expect = 0.47 Identities = 19/74 (25%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +1 Query: 40 VQHLFWDTVGENLT-KRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIG 216 + +LF+D + + ++ ++ LR E A FD+EAN ++ + A+++++ Sbjct: 220 ILNLFFDKITFEIAGDKLLMTLVPERLRGETASFDIEANGKVYVERGRRITARHIKALEK 279 Query: 217 DRISVIVQNSALML 258 D IS +V S +L Sbjct: 280 DNISQVVVPSEYIL 293
>RPOB_HAEI8 (Q4QN33) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1343 Score = 31.6 bits (70), Expect = 0.47 Identities = 19/74 (25%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +1 Query: 40 VQHLFWDTVGENLT-KRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIG 216 + +LF+D + + ++ ++ LR E A FD+EAN ++ + A+++++ Sbjct: 220 ILNLFFDKITFEIAGDKLLMTLVPERLRGETASFDIEANGKVYVERGRRITARHIKALEK 279 Query: 217 DRISVIVQNSALML 258 D IS +V S +L Sbjct: 280 DNISQVVVPSEYIL 293
>ABCBA_HUMAN (Q9NRK6) ATP-binding cassette sub-family B member 10, mitochondrial| precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2) Length = 738 Score = 31.6 bits (70), Expect = 0.47 Identities = 15/65 (23%), Positives = 34/65 (52%) Frame = +1 Query: 34 NTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAI 213 N ++ T G+ + R+R + +++LR E+A+FD + + RL+ D + ++ Sbjct: 229 NAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFD--KTRTGELINRLSSDTALLGRSV 286 Query: 214 GDRIS 228 + +S Sbjct: 287 TENLS 291
>RPOB_PHOLL (Q7N9A4) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 31.2 bits (69), Expect = 0.61 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Frame = +1 Query: 52 FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGD---R 222 F T+ E R++ ++ LR E A FD+EAN ++ + A+++R D R Sbjct: 225 FSKTIFEIRDNRLQMTLVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDEVNR 284 Query: 223 ISVIVQNSALMLVA 264 I V V+ A +VA Sbjct: 285 IEVPVEYIAGKVVA 298
>RPOB_ERWCT (Q6DAN0) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 30.4 bits (67), Expect = 1.0 Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQ--HLFWDTVGENLT-KRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL ++T Q LF+D + + +++ ++ LR E A FD+EAN +I + A Sbjct: 212 ALGYSTAQILDLFFDKIVYEINGNKLQMDLVPERLRGETASFDIEANGKVYIEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D I I Sbjct: 272 RHIRQLEKDSIERI 285
>Y4GM_RHISN (P55469) Probable ABC transporter ATP-binding protein y4gM| Length = 586 Score = 30.4 bits (67), Expect = 1.0 Identities = 17/58 (29%), Positives = 30/58 (51%) Frame = +1 Query: 40 VQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAI 213 VQ +F G N+ + ++ VLR ++++ + S+ + RL +AQ VRS I Sbjct: 86 VQSIFLSKAGNNIIAHTQRRLFEHVLRQGLSFYSI--YPSSELLVRLTNNAQAVRSVI 141
>RPOB_SHISS (Q3YUZ7) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 30.0 bits (66), Expect = 1.4 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F + E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D + +I Sbjct: 272 RHIRQLEKDDVKLI 285
>RPOB_SHIFL (P0A8V5) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 30.0 bits (66), Expect = 1.4 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F + E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D + +I Sbjct: 272 RHIRQLEKDDVKLI 285
>RPOB_SHIDS (Q32AF9) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 30.0 bits (66), Expect = 1.4 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F + E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D + +I Sbjct: 272 RHIRQLEKDDVKLI 285
>RPOB_SHIBS (Q31U10) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 30.0 bits (66), Expect = 1.4 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F + E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D + +I Sbjct: 272 RHIRQLEKDDVKLI 285
>RPOB_PASMU (Q9CK91) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 30.0 bits (66), Expect = 1.4 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL--FWD-TVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F+D V E ++ ++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDIFFDKVVFEISNNKLLMTLVPERLRGETATFDIEANGKVYVERGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R+ D+I+ + Sbjct: 272 RHIRALEKDQITQV 285
>RPOB_ECOLI (P0A8V2) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 30.0 bits (66), Expect = 1.4 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F + E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D + +I Sbjct: 272 RHIRQLEKDDVKLI 285
>RPOB_ECOL6 (P0A8V3) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 30.0 bits (66), Expect = 1.4 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F + E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D + +I Sbjct: 272 RHIRQLEKDDVKLI 285
>RPOB_ECO57 (P0A8V4) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 30.0 bits (66), Expect = 1.4 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F + E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D + +I Sbjct: 272 RHIRQLEKDDVKLI 285
>MDL1_CANAL (P97998) ATP-dependent permease MDL1| Length = 685 Score = 30.0 bits (66), Expect = 1.4 Identities = 19/83 (22%), Positives = 39/83 (46%), Gaps = 8/83 (9%) Frame = +1 Query: 61 TVGENLTKRVREKMLTAVLRNEMAWFDMEAN----ASAHIAARLALDAQNVRSA----IG 216 +VGE L R+R ++ + +L + +FD+ + + + +R+A D Q + + I Sbjct: 182 SVGERLVARLRSRLFSKILAQDAYFFDLGPSKTGMKTGDLISRIASDTQIISKSLSMNIS 241 Query: 217 DRISVIVQNSALMLVACTAGFVL 285 D I I+ + + C + L Sbjct: 242 DGIRAIISGCVGLSMMCYVSWKL 264
>MSBA_FRANO (Q47908) Lipid A export ATP-binding/permease protein msbA| Length = 593 Score = 30.0 bits (66), Expect = 1.4 Identities = 18/98 (18%), Positives = 44/98 (44%) Frame = +1 Query: 1 LIGMSSAALLFNTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARL 180 ++G + + + V F ++G+ + + R+ + ++ ++FD +++ I +RL Sbjct: 75 MVGFIALRSVGSFVSQYFIGSLGQKVVYKFRKDIYKRLMDLPASFFDK--HSTGQIISRL 132 Query: 181 ALDAQNVRSAIGDRISVIVQNSALMLVACTAGFVLQWR 294 + V A I +VQ+ ++ FV W+ Sbjct: 133 LYNVDQVTEATSTAIITVVQDGTFVIGLIVVMFVSSWQ 170
>RPOB_SALTY (P06173) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 29.6 bits (65), Expect = 1.8 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F V E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D I I Sbjct: 272 RHIRQLEKDDIKHI 285
>RPOB_SALTI (Q8Z320) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 29.6 bits (65), Expect = 1.8 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F V E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D I I Sbjct: 272 RHIRQLEKDDIKHI 285
>RPOB_SALPA (Q5PK93) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 29.6 bits (65), Expect = 1.8 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F V E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D I I Sbjct: 272 RHIRQLEKDDIKHI 285
>RPOB_SALCH (Q57H69) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 29.6 bits (65), Expect = 1.8 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL---FWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F V E +++ +++ LR E A FD+EAN ++ + A Sbjct: 212 ALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D I I Sbjct: 272 RHIRQLEKDDIKHI 285
>ABCBA_MOUSE (Q9JI39) ATP-binding cassette sub-family B member 10, mitochondrial| precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein) Length = 715 Score = 29.6 bits (65), Expect = 1.8 Identities = 14/65 (21%), Positives = 35/65 (53%) Frame = +1 Query: 34 NTVQHLFWDTVGENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAI 213 N ++ + G+++ R+R + +++LR E+A+FD + + RL+ D + ++ Sbjct: 194 NGIRVYLMQSSGQSIVNRLRTSLFSSILRQEVAFFD--KTRTGELINRLSSDTALLGRSV 251 Query: 214 GDRIS 228 + +S Sbjct: 252 TENLS 256
>CENPC_MOUSE (P49452) Centromere protein C 1 (CENP-C) (Centromere autoantigen C)| Length = 906 Score = 29.6 bits (65), Expect = 1.8 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 5/70 (7%) Frame = -2 Query: 386 SRSPEKPFMNIFCSTVAPTTS-GKTARSTSARRHCRTNPAVHATSISAEFCTMTEM---- 222 SRS KP I + + + R R + T+P VH S + E+ + T+M Sbjct: 575 SRSQRKPLKIIEADPTQKSLAISRPKRGCKYRNNVMTSPNVHLKSHTEEYTSKTQMESAS 634 Query: 221 RSPMAERTFW 192 S M++R+ W Sbjct: 635 NSEMSKRSVW 644
>AROA_CAMJE (P52312) 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19)| (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) Length = 428 Score = 28.9 bits (63), Expect = 3.0 Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 7/84 (8%) Frame = +1 Query: 22 ALLFNTVQHLFWDTVGENLTKRVREKMLTAV-LRNEMAWFDMEANASAHIAARLA----- 183 A L T+ ++T+GE RV L + +++ +AW EA A A IA LA Sbjct: 275 AKLEMTITQNDFETIGEI---RVESSKLNGIEVKDNIAWLIDEAPALA-IAFALAKGKSS 330 Query: 184 -LDAQNVRSAIGDRISVIVQNSAL 252 ++A+ +R DRI+V+V+N L Sbjct: 331 LINAKELRVKESDRIAVMVENLKL 354
>ILVD_SYNY3 (P74689) Dihydroxy-acid dehydratase (EC 4.2.1.9) (DAD)| Length = 561 Score = 28.9 bits (63), Expect = 3.0 Identities = 13/37 (35%), Positives = 19/37 (51%) Frame = -1 Query: 141 VEPGHLVAEHRREHLLAHAFGQVLADRVPEEVLHGVE 31 ++PGH E A GQ A ++ EE L+G+E Sbjct: 149 IKPGHYAGEDLTVVSAFEAVGQYSAGKIDEETLYGIE 185
>SYI_HALSA (Q9HN97) Isoleucyl-tRNA synthetase (EC 6.1.1.5) (Isoleucine--tRNA| ligase) (IleRS) Length = 1070 Score = 28.9 bits (63), Expect = 3.0 Identities = 32/101 (31%), Positives = 40/101 (39%), Gaps = 23/101 (22%) Frame = -1 Query: 234 DDGD------AVPDGGAHVLGVQREPGGYVRAGVGLHVEPGHLVAEHRREHLLAHAFGQV 73 +DGD PDG VL V E V + G +VA+H L+ ++ Sbjct: 239 EDGDYQQVRATTPDGETDVLYVASECVEDVLSAGGY--SDHEIVADHSGSDLIGWSYTPP 296 Query: 72 LADRVP---------EEVLHG--VEEQRRG------GHADE 1 LAD VP EV HG VE R G GH +E Sbjct: 297 LADAVPANPTDADGTHEVYHGDWVEADRTGLVHSAPGHGEE 337
>RPOB_MANSM (Q65W41) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 28.5 bits (62), Expect = 4.0 Identities = 13/40 (32%), Positives = 23/40 (57%) Frame = +1 Query: 115 LRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 LR E A FD+EAN ++ + A+++R+ D ++ I Sbjct: 246 LRGETASFDIEANGKVYVERGRRITARHIRTLEKDNVTKI 285
>ZAN_MOUSE (O88799) Zonadhesin precursor| Length = 5376 Score = 28.5 bits (62), Expect = 4.0 Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 1/35 (2%) Frame = -1 Query: 234 DDGDAVPDGGAHVLGVQREPGGYVRA-GVGLHVEP 133 DDGD + G + G PGGY G LH++P Sbjct: 65 DDGDWIRTTGPSLTGTSGPPGGYPNGEGYYLHMDP 99
>RPOA_CHLTR (Q46449) DNA-directed RNA polymerase alpha chain (EC 2.7.7.6) (RNAP| alpha subunit) (Transcriptase alpha chain) (RNA polymerase alpha subunit) Length = 377 Score = 28.5 bits (62), Expect = 4.0 Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 9/114 (7%) Frame = -1 Query: 390 AFQVTGEALHEHLLQHG----GANXXXXXXXXXXXEAPLQDEPGGACDEHKRRVLH-DDG 226 +F +TG LHE++ G N + PLQD GG C + R + D Sbjct: 69 SFSMTG-VLHEYMAVEGIIEDVTNIVLNLKGSLLKKYPLQDCEGGRCSQKLRATISIDAS 127 Query: 225 DAVPDGGAHVLGVQREPGGYVRAGVGLHVEPGHLVAEHRR----EHLLAHAFGQ 76 D GG + + G ++ G V P H++ R E +L AFG+ Sbjct: 128 DLAAAGGQKEVTL----GDLLQEGTFEAVNPEHVIFTVTRPMQLEVMLRVAFGR 177
>RPOA_CHLTA (Q3KLJ0) DNA-directed RNA polymerase alpha chain (EC 2.7.7.6) (RNAP| alpha subunit) (Transcriptase alpha chain) (RNA polymerase alpha subunit) Length = 377 Score = 28.5 bits (62), Expect = 4.0 Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 9/114 (7%) Frame = -1 Query: 390 AFQVTGEALHEHLLQHG----GANXXXXXXXXXXXEAPLQDEPGGACDEHKRRVLH-DDG 226 +F +TG LHE++ G N + PLQD GG C + R + D Sbjct: 69 SFSMTG-VLHEYMAVEGIIEDVTNIVLNLKGSLLKKYPLQDCEGGRCSQKLRATISIDAS 127 Query: 225 DAVPDGGAHVLGVQREPGGYVRAGVGLHVEPGHLVAEHRR----EHLLAHAFGQ 76 D GG + + G ++ G V P H++ R E +L AFG+ Sbjct: 128 DLAAAGGQKEVTL----GDLLQEGTFEAVNPEHVIFTVTRPMQLEVMLRVAFGR 177
>RPOB_PHOPR (Q6LLW2) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1341 Score = 28.1 bits (61), Expect = 5.2 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNTVQHL--FWDTVG-ENLTKRVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL + T Q L F+D V E K + +++ LR E A FD+EAN ++ + A Sbjct: 212 ALDYTTEQILDMFFDKVSFEVQGKSLVMELVPERLRGETASFDIEANGKVYVEQGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 +++R D + I Sbjct: 272 RHIRQLGKDGVDQI 285
>ALGK_PSEAE (P96956) Alginate biosynthesis protein algK precursor| Length = 475 Score = 28.1 bits (61), Expect = 5.2 Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 4/55 (7%) Frame = -1 Query: 228 GDAVPDGGAHVL---GVQREPGGYVRAGVGLHVEPGHLVAEHRR-EHLLAHAFGQ 76 GD+ A L Q P R G L +PG AEHR E LL+ AF Q Sbjct: 76 GDSAQQAKAEKLYREAAQTSPRARARLGKWLAAKPGASDAEHREAERLLSQAFEQ 130
>TSP4_HUMAN (P35443) Thrombospondin-4 precursor| Length = 961 Score = 28.1 bits (61), Expect = 5.2 Identities = 15/52 (28%), Positives = 24/52 (46%) Frame = -2 Query: 398 ACAPSRSPEKPFMNIFCSTVAPTTSGKTARSTSARRHCRTNPAVHATSISAE 243 AC P+ + C P +G R A R+CR NP ++ S++A+ Sbjct: 387 ACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCR-NPELNPCSVNAQ 437
>RPOB_HAEDU (Q7VKL7) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 27.7 bits (60), Expect = 6.8 Identities = 14/40 (35%), Positives = 23/40 (57%) Frame = +1 Query: 115 LRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVI 234 LR E A FD+EAN ++ + A+++R+ D I+ I Sbjct: 246 LRGETAAFDIEANGKIYVERGRRITARHIRTLEKDGITQI 285
>RPOB_BUCAP (P41184) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 27.7 bits (60), Expect = 6.8 Identities = 18/74 (24%), Positives = 42/74 (56%), Gaps = 3/74 (4%) Frame = +1 Query: 22 ALLFNT--VQHLFWDTVGENLTK-RVREKMLTAVLRNEMAWFDMEANASAHIAARLALDA 192 AL +NT + +LF++ N+ +++ ++++ LR E A FD++ N ++ + A Sbjct: 212 ALNYNTEEILNLFFEKNIFNINNNKIQLELVSERLRGETASFDIKKNGKIYVKKGRRITA 271 Query: 193 QNVRSAIGDRISVI 234 ++++ D+I+ I Sbjct: 272 KHIQELKKDKINSI 285
>Y1369_HAEIN (P45182) Hypothetical protein HI1369| Length = 839 Score = 27.7 bits (60), Expect = 6.8 Identities = 13/26 (50%), Positives = 18/26 (69%), Gaps = 1/26 (3%) Frame = -2 Query: 374 EKPFMNIFCST-VAPTTSGKTARSTS 300 +KP M +FCST V+P GKT +T+ Sbjct: 43 KKPLMLLFCSTFVSPFVMGKTIETTN 68
>DPOL_HHV6U (P28857) DNA polymerase (EC 2.7.7.7)| Length = 1012 Score = 27.7 bits (60), Expect = 6.8 Identities = 17/50 (34%), Positives = 27/50 (54%) Frame = +1 Query: 88 VREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIGDRISVIV 237 VR ML++VL EMA + A + RLA + + + +GDRI ++ Sbjct: 882 VRHLMLSSVLSKEMAAYKQPNLAHLSVIRRLAQRKEEIPN-VGDRIMYVL 930
>GSH1_VIBPA (Q87LS2) Glutamate--cysteine ligase (EC 6.3.2.2)| (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS) Length = 522 Score = 27.7 bits (60), Expect = 6.8 Identities = 19/65 (29%), Positives = 30/65 (46%) Frame = -1 Query: 198 VLGVQREPGGYVRAGVGLHVEPGHLVAEHRREHLLAHAFGQVLADRVPEEVLHGVEEQRR 19 +L + +E GG + G L ++ RE LAH + D + EV VE+QR+ Sbjct: 449 LLELTKELGGLGKVGCALGMK--------FREENLAHGYQHYSQDIMETEVASSVEKQRK 500 Query: 18 GGHAD 4 +D Sbjct: 501 AEESD 505
>KAD_DEIRA (Q9RSK7) Adenylate kinase (EC 2.7.4.3) (ATP-AMP transphosphorylase)| Length = 197 Score = 27.7 bits (60), Expect = 6.8 Identities = 12/25 (48%), Positives = 16/25 (64%) Frame = +3 Query: 9 HVLRGAALQHRAAPLLGHGRREPDQ 83 HV RG AL +A PL+ G+ PD+ Sbjct: 44 HVARGTALGQQAGPLMEAGQLVPDE 68
>RPOB_WIGBR (Q8D233) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (RNAP| beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1342 Score = 27.3 bits (59), Expect = 8.9 Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = +1 Query: 40 VQHLFWDTVGENLTKR-VREKMLTAVLRNEMAWFDMEANASAHIAARLALDAQNVRSAIG 216 + ++F++ V + K+ + +++ LR E A FD+ N +I + A+++R+ Sbjct: 219 ILNIFFEKVNFFIRKKNLLMELIPKRLRGETALFDICENGITYIKKGRRITAKHIRNLEN 278 Query: 217 DRISVI 234 D+IS I Sbjct: 279 DKISQI 284
>MED3_YEAST (P40356) RNA polymerase II mediator complex subunit 3| (Poly-glutamine domain protein 1) (Hyper-recombination suppressor protein 1) Length = 397 Score = 27.3 bits (59), Expect = 8.9 Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 4/55 (7%) Frame = -2 Query: 359 NIFCSTVAPTTSGKTARS----TSARRHCRTNPAVHATSISAEFCTMTEMRSPMA 207 N CST ++ +A + T+A H NP HA S+S T T +P+A Sbjct: 130 NAVCSTATVVSTNHSAAASTPTTTATPHA--NPITHAHSLSNPNSTATMQHNPLA 182
>APLP2_MOUSE (Q06335) Amyloid-like protein 2 precursor (CDEI box-binding| protein) (CDEBP) Length = 695 Score = 27.3 bits (59), Expect = 8.9 Identities = 17/60 (28%), Positives = 29/60 (48%) Frame = -1 Query: 201 HVLGVQREPGGYVRAGVGLHVEPGHLVAEHRREHLLAHAFGQVLADRVPEEVLHGVEEQR 22 HVL V E +++ V H+ H++ E R + L +A + EE+ ++EQR Sbjct: 457 HVLAVDPEKAAQMKSQVMTHL---HVIEERRNQSLTLLYKVPYVAQEIQEEIDELLQEQR 513
>SYA_PSEAE (Q9I553) Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine--tRNA ligase)| (AlaRS) Length = 874 Score = 27.3 bits (59), Expect = 8.9 Identities = 24/70 (34%), Positives = 28/70 (40%), Gaps = 5/70 (7%) Frame = -1 Query: 243 VLHDDGDAVPDGGAH-----VLGVQREPGGYVRAGVGLHVEPGHLVAEHRREHLLAHAFG 79 V D D GGAH V GG V+A V V + H HLL A Sbjct: 515 VRFDVRDTTKAGGAHLHHGVVARGNLSVGGAVKAEVDASVRQATAL-NHSATHLLHAALR 573 Query: 78 QVLADRVPEE 49 QVL D V ++ Sbjct: 574 QVLGDHVQQK 583
>ERG7_MOUSE (Q8BLN5) Lanosterol synthase (EC 5.4.99.7)| (Oxidosqualene--lanosterol cyclase) (2,3-epoxysqualene--lanosterol cyclase) (OSC) Length = 733 Score = 27.3 bits (59), Expect = 8.9 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 2/34 (5%) Frame = +3 Query: 21 GAALQHRAAPLLGHGRREPDQTRAREDAH--GGA 116 G AL + A +LG G +PD RAR H GGA Sbjct: 154 GTALNYVALRILGIGPDDPDLVRARNVLHKKGGA 187
>ANC2_CAEEL (P34514) Anaphase-promoting complex subunit 2 (APC2) (Cyclosome| subunit 2) Length = 728 Score = 27.3 bits (59), Expect = 8.9 Identities = 16/54 (29%), Positives = 24/54 (44%) Frame = -1 Query: 240 LHDDGDAVPDGGAHVLGVQREPGGYVRAGVGLHVEPGHLVAEHRREHLLAHAFG 79 L DD D P+ + ++ + GY R + H G + AE R H + FG Sbjct: 635 LEDDEDVEPEENSDMVDALEQYWGYTRNFIANHAPNGEVKAE--RMHRVYRMFG 686 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,626,212 Number of Sequences: 219361 Number of extensions: 829509 Number of successful extensions: 3293 Number of sequences better than 10.0: 96 Number of HSP's better than 10.0 without gapping: 3172 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3271 length of database: 80,573,946 effective HSP length: 111 effective length of database: 56,224,875 effective search space used: 1349397000 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
