ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bast60b07 |
|---|---|
| Clone Library Name | barley_pub |
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 102 bits (254), Expect = 5e-22 Identities = 65/157 (41%), Positives = 89/157 (56%), Gaps = 10/157 (6%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH--STHNLAHG 179 D KLLVY+Y+PNGSL+ +LHG R G + W R+R AL A+ GL++LH + H Sbjct: 760 DCKLLVYEYMPNGSLADVLHGDR-KGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVHR 818 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTR--------AGAGGYRAPEVVDTRRPTF 335 +VKSSN+LL DY A ++DF + + S ++ AG+ GY APE V T R Sbjct: 819 DVKSSNILLDSDY-GAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNE 877 Query: 336 KADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWV 446 K+D+YS TGK PT + L G D+ +WV Sbjct: 878 KSDIYSFGVVLLELVTGKQPTDSEL---GDKDMAKWV 911
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 95.5 bits (236), Expect = 6e-20 Identities = 61/162 (37%), Positives = 89/162 (54%), Gaps = 8/162 (4%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN--LAH 176 KD LL+Y+Y+PNGSL +LHGS+G + W+ R R A+ A++GL +LH + + H Sbjct: 759 KDTNLLLYEYMPNGSLGELLHGSKGG---HLQWETRHRVAVEAAKGLCYLHHDCSPLILH 815 Query: 177 GNVKSSNVLLRLDYDAAALSDFCLHPIFAPS------STRAGAGGYRAPEVVDTRRPTFK 338 +VKS+N+LL D++ A ++DF L S+ AG+ GY APE T + K Sbjct: 816 RDVKSNNILLDSDFE-AHVADFGLAKFLVDGAASECMSSIAGSYGYIAPEYAYTLKVDEK 874 Query: 339 ADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 +DVYS GK P EG +D+ RWV++ E Sbjct: 875 SDVYSFGVVLLELIAGKKPVGEFGEG---VDIVRWVRNTEEE 913
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 90.9 bits (224), Expect = 1e-18 Identities = 57/161 (35%), Positives = 91/161 (56%), Gaps = 7/161 (4%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN--LAH 176 + EKLL+YDYLPN SL +LH S+ + ++W R + AL +RGLA+LH+ + H Sbjct: 440 RGEKLLIYDYLPNISLHDLLHESKPR-KPALNWARRHKIALGIARGLAYLHTGQEVPIIH 498 Query: 177 GNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS-----TRAGAGGYRAPEVVDTRRPTFKA 341 GN++S NVL+ D+ A L++F L I + ++A + GY+APE+ ++ ++ Sbjct: 499 GNIRSKNVLVD-DFFFARLTEFGLDKIMVQAVADEIVSQAKSDGYKAPELHKMKKCNPRS 557 Query: 342 DVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 DVY+ GK P + G+ +DLP V++ V E Sbjct: 558 DVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLE 598
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 90.5 bits (223), Expect = 2e-18 Identities = 60/161 (37%), Positives = 85/161 (52%), Gaps = 8/161 (4%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHST--HNLAHG 179 +E+LLVY+Y+ GSL +LH G +DW AR + A+ A+RGLA LH + ++ H Sbjct: 925 EERLLVYEYMKYGSLETVLHEKTKKGGIFLDWSARKKIAIGAARGLAFLHHSCIPHIIHR 984 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFA------PSSTRAGAGGYRAPEVVDTRRPTFKA 341 ++KSSNVLL D+ A +SDF + + + ST AG GY PE + R T K Sbjct: 985 DMKSSNVLLDQDF-VARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKG 1043 Query: 342 DVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 DVYS +GK P G+ +L W + + RE Sbjct: 1044 DVYSYGVILLELLSGKKPIDPEEFGEDN-NLVGWAKQLYRE 1083
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 87.0 bits (214), Expect = 2e-17 Identities = 59/161 (36%), Positives = 81/161 (50%), Gaps = 7/161 (4%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHST--HNLAH 176 K++KLL+Y Y+ NGSL LH + G +DW R+R A A+ GLA+LH + ++ H Sbjct: 809 KNDKLLIYSYMDNGSLDYWLH-EKVDGPPSLDWKTRLRIARGAAEGLAYLHQSCEPHILH 867 Query: 177 GNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTR-----AGAGGYRAPEVVDTRRPTFKA 341 ++KSSN+LL D A L+DF L + P T G GY PE T+K Sbjct: 868 RDIKSSNILLS-DTFVAHLADFGLARLILPYDTHVTTDLVGTLGYIPPEYGQASVATYKG 926 Query: 342 DVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 DVYS TG+ P + G+ DL WV + E Sbjct: 927 DVYSFGVVLLELLTGRRPMDV-CKPRGSRDLISWVLQMKTE 966
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 86.7 bits (213), Expect = 3e-17 Identities = 58/137 (42%), Positives = 79/137 (57%), Gaps = 9/137 (6%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHS--THNLAHG 179 D++LLVY+Y+P GSL LH SG+ P+DW+ RM+ A A+RGL +LH T + + Sbjct: 171 DQRLLVYEYMPQGSLEDHLH-VLPSGKKPLDWNTRMKIAAGAARGLEYLHDRMTPPVIYR 229 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPS------STRA-GAGGYRAPEVVDTRRPTFK 338 ++K SN+LL DY LSDF L + PS STR G GY AP+ T + TFK Sbjct: 230 DLKCSNILLGEDYQ-PKLSDFGLAKV-GPSGDKTHVSTRVMGTYGYCAPDYAMTGQLTFK 287 Query: 339 ADVYSXXXXXXXXXTGK 389 +D+YS TG+ Sbjct: 288 SDIYSFGVVLLELITGR 304
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 86.3 bits (212), Expect = 4e-17 Identities = 59/151 (39%), Positives = 84/151 (55%), Gaps = 10/151 (6%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN----LA 173 +E+LLVY+Y+ GSL +LH + +G ++W AR + A+ A+RGLA LH HN + Sbjct: 955 EERLLVYEYMKYGSLEDVLHDRKKTG-IKLNWPARRKIAIGAARGLAFLH--HNCIPHII 1011 Query: 174 HGNVKSSNVLLRLDYDAAALSDFCLHPIFAPS------STRAGAGGYRAPEVVDTRRPTF 335 H ++KSSNVLL + +A +SDF + + + ST AG GY PE + R + Sbjct: 1012 HRDMKSSNVLLDENLEAR-VSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCST 1070 Query: 336 KADVYSXXXXXXXXXTGKSPTHASLEGDGTL 428 K DVYS TGK PT ++ GD L Sbjct: 1071 KGDVYSYGVVLLELLTGKQPTDSADFGDNNL 1101
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 85.1 bits (209), Expect = 8e-17 Identities = 59/151 (39%), Positives = 83/151 (54%), Gaps = 10/151 (6%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN----LA 173 +E+LLVY+Y+ GSL +LH + G ++W AR + A+ A+RGLA LH HN + Sbjct: 955 EERLLVYEYMKYGSLEDVLHDRKKIG-IKLNWPARRKIAIGAARGLAFLH--HNCIPHII 1011 Query: 174 HGNVKSSNVLLRLDYDAAALSDFCLHPIFAPS------STRAGAGGYRAPEVVDTRRPTF 335 H ++KSSNVLL + +A +SDF + + + ST AG GY PE + R + Sbjct: 1012 HRDMKSSNVLLDENLEAR-VSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCST 1070 Query: 336 KADVYSXXXXXXXXXTGKSPTHASLEGDGTL 428 K DVYS TGK PT ++ GD L Sbjct: 1071 KGDVYSYGVVLLELLTGKQPTDSADFGDNNL 1101
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 84.7 bits (208), Expect = 1e-16 Identities = 62/164 (37%), Positives = 85/164 (51%), Gaps = 11/164 (6%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSR-GSGRTPMDWDARMRSALSASRGLAHLHSTHN----L 170 +E+LLVY+++ GSL +LHG R G R + W+ R + A A++GL LH HN + Sbjct: 905 EERLLVYEFMQYGSLEEVLHGPRTGEKRRILGWEERKKIAKGAAKGLCFLH--HNCIPHI 962 Query: 171 AHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPS------STRAGAGGYRAPEVVDTRRPT 332 H ++KSSNVLL D +A +SDF + + + ST AG GY PE + R T Sbjct: 963 IHRDMKSSNVLLDQDMEAR-VSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCT 1021 Query: 333 FKADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 K DVYS +GK PT GD +L W + RE Sbjct: 1022 AKGDVYSIGVVMLEILSGKRPTDKEEFGD--TNLVGWSKMKARE 1063
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 84.7 bits (208), Expect = 1e-16 Identities = 60/162 (37%), Positives = 87/162 (53%), Gaps = 9/162 (5%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHG-SRGSGRTPMDWDARMRSALSASRGLAHLHST--HNLAH 176 +E+LLVY+Y+ GSL +LH S G ++W AR + A+ A+RGLA LH + ++ H Sbjct: 926 EERLLVYEYMKWGSLETVLHEKSSKKGGIYLNWAARKKIAIGAARGLAFLHHSCIPHIIH 985 Query: 177 GNVKSSNVLLRLDYDAAALSDFCLHPIFAPS------STRAGAGGYRAPEVVDTRRPTFK 338 ++KSSNVLL D++A +SDF + + + ST AG GY PE + R T K Sbjct: 986 RDMKSSNVLLDEDFEAR-VSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAK 1044 Query: 339 ADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 DVYS +GK P G+ +L W + + RE Sbjct: 1045 GDVYSYGVILLELLSGKKPIDPGEFGEDN-NLVGWAKQLYRE 1085
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 83.2 bits (204), Expect = 3e-16 Identities = 55/149 (36%), Positives = 82/149 (55%), Gaps = 8/149 (5%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHS--THNLAHG 179 DE+LLVY+++ GSL +LH + +G ++W R + A+ ++RGLA LH + ++ H Sbjct: 950 DERLLVYEFMKYGSLEDVLHDPKKAG-VKLNWSTRRKIAIGSARGLAFLHHNCSPHIIHR 1008 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPS------STRAGAGGYRAPEVVDTRRPTFKA 341 ++KSSNVLL + +A +SDF + + + ST AG GY PE + R + K Sbjct: 1009 DMKSSNVLLDENLEAR-VSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKG 1067 Query: 342 DVYSXXXXXXXXXTGKSPTHASLEGDGTL 428 DVYS TGK PT + GD L Sbjct: 1068 DVYSYGVVLLELLTGKRPTDSPDFGDNNL 1096
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 82.4 bits (202), Expect = 5e-16 Identities = 53/138 (38%), Positives = 75/138 (54%), Gaps = 7/138 (5%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTH--NLAHG 179 +EKLLVY+Y+ NGSL L G +DW R++ A+ A+RGLA LH ++ H Sbjct: 984 EEKLLVYEYMVNGSLDHWLRNQTGMLEV-LDWSKRLKIAVGAARGLAFLHHGFIPHIIHR 1042 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAP-----SSTRAGAGGYRAPEVVDTRRPTFKAD 344 ++K+SN+LL D++ ++DF L + + S+ AG GY PE + R T K D Sbjct: 1043 DIKASNILLDGDFEPK-VADFGLARLISACESHVSTVIAGTFGYIPPEYGQSARATTKGD 1101 Query: 345 VYSXXXXXXXXXTGKSPT 398 VYS TGK PT Sbjct: 1102 VYSFGVILLELVTGKEPT 1119
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 81.3 bits (199), Expect = 1e-15 Identities = 55/161 (34%), Positives = 80/161 (49%), Gaps = 7/161 (4%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHS--THNLAH 176 K+++LL+Y Y+ NGSL LH R G + W R+R A A++GL +LH ++ H Sbjct: 800 KNDRLLIYSYMENGSLDYWLH-ERNDGPALLKWKTRLRIAQGAAKGLLYLHEGCDPHILH 858 Query: 177 GNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTR-----AGAGGYRAPEVVDTRRPTFKA 341 ++KSSN+LL +++ + L+DF L + +P T G GY PE T+K Sbjct: 859 RDIKSSNILLDENFN-SHLADFGLARLMSPYETHVSTDLVGTLGYIPPEYGQASVATYKG 917 Query: 342 DVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 DVYS T K P + G DL WV + E Sbjct: 918 DVYSFGVVLLELLTDKRPVD-MCKPKGCRDLISWVVKMKHE 957
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 79.0 bits (193), Expect = 6e-15 Identities = 53/160 (33%), Positives = 84/160 (52%), Gaps = 8/160 (5%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHS--THNLAHGN 182 E+LLVY Y+ NGS+++ L R + P+DW R R AL ++RGLA+LH + H + Sbjct: 358 ERLLVYPYMANGSVASCLR-ERPESQPPLDWPKRQRIALGSARGLAYLHDHCDPKIIHRD 416 Query: 183 VKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRA-----GAGGYRAPEVVDTRRPTFKADV 347 VK++N+LL +++ A + DF L + T G G+ APE + T + + K DV Sbjct: 417 VKAANILLDEEFE-AVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDV 475 Query: 348 YSXXXXXXXXXTGKSPTH-ASLEGDGTLDLPRWVQSVVRE 464 + TG+ A L D + L WV+ +++E Sbjct: 476 FGYGVMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKE 515
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 75.9 bits (185), Expect = 5e-14 Identities = 58/155 (37%), Positives = 83/155 (53%), Gaps = 7/155 (4%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTH-NLAHGN 182 + +LLVY+++P GSL L RG P+ W R++ AL A++GLA LHS+ + + + Sbjct: 145 EHRLLVYEFMPRGSLENHLF-RRGLYFQPLSWKLRLKVALGAAKGLAFLHSSETRVIYRD 203 Query: 183 VKSSNVLLRLDYDAAALSDFCL---HPIFAPS--STRA-GAGGYRAPEVVDTRRPTFKAD 344 K+SN+LL +Y+ A LSDF L PI S STR G GY APE + T T K+D Sbjct: 204 FKTSNILLDSEYN-AKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATGHLTTKSD 262 Query: 345 VYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQ 449 VYS +G+ + G +L W + Sbjct: 263 VYSFGVVLLELLSGRRAVDKN-RPSGERNLVEWAK 296
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 74.7 bits (182), Expect = 1e-13 Identities = 57/154 (37%), Positives = 79/154 (51%), Gaps = 8/154 (5%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH--STHNLAHG 179 +EKLLVY+Y+P G+LS L G P+ W R+ AL +RG+ +LH + + H Sbjct: 657 NEKLLVYEYMPQGTLSRHLFEWSEEGLKPLLWKQRLTLALDVARGVEYLHGLAHQSFIHR 716 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPS-----STR-AGAGGYRAPEVVDTRRPTFKA 341 ++K SN+LL D A ++DF L + AP TR AG GY APE T R T K Sbjct: 717 DLKPSNILLGDDM-RAKVADFGLVRL-APEGKGSIETRIAGTFGYLAPEYAVTGRVTTKV 774 Query: 342 DVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRW 443 DVYS TG+ S + + ++ L W Sbjct: 775 DVYSFGVILMELITGRKSLDES-QPEESIHLVSW 807
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 73.9 bits (180), Expect = 2e-13 Identities = 53/123 (43%), Positives = 74/123 (60%), Gaps = 7/123 (5%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTH-NLAHGN 182 + +LLVY+++P GSL L RGS P+ W R++ AL A++GLA LH+ ++ + + Sbjct: 146 EHRLLVYEFMPRGSLENHLF-RRGSYFQPLSWTLRLKVALGAAKGLAFLHNAETSVIYRD 204 Query: 183 VKSSNVLLRLDYDAAALSDFCL---HPIFAPS--STR-AGAGGYRAPEVVDTRRPTFKAD 344 K+SN+LL +Y+ A LSDF L P S STR G GY APE + T T K+D Sbjct: 205 FKTSNILLDSEYN-AKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATGHLTTKSD 263 Query: 345 VYS 353 VYS Sbjct: 264 VYS 266
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 73.2 bits (178), Expect = 3e-13 Identities = 52/124 (41%), Positives = 75/124 (60%), Gaps = 7/124 (5%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTH-NLAHG 179 ++ +LLVY+++ GSL L RG+ P+ W+ R+R AL A+RGLA LH+ + + Sbjct: 144 EEHRLLVYEFMTRGSLENHLF-RRGTFYQPLSWNTRVRMALGAARGLAFLHNAQPQVIYR 202 Query: 180 NVKSSNVLLRLDYDAAALSDFCL---HPIFAPS--STRA-GAGGYRAPEVVDTRRPTFKA 341 + K+SN+LL +Y+ A LSDF L P+ S STR G GY APE + T + K+ Sbjct: 203 DFKASNILLDSNYN-AKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATGHLSVKS 261 Query: 342 DVYS 353 DVYS Sbjct: 262 DVYS 265
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 72.4 bits (176), Expect = 5e-13 Identities = 52/159 (32%), Positives = 78/159 (49%), Gaps = 8/159 (5%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN--LAH 176 K+ L++Y Y+ NGSL +LH + P+DW R A+ + GLA+LH + + H Sbjct: 883 KEYGLILYTYMENGSLHDILHETNPP--KPLDWSTRHNIAVGTAHGLAYLHFDCDPAIVH 940 Query: 177 GNVKSSNVLLRLDYDAAALSDFCLHPIF------APSSTRAGAGGYRAPEVVDTRRPTFK 338 ++K N+LL D + +SDF + + PS+T G GY APE T + + Sbjct: 941 RDIKPMNILLDSDLEPH-ISDFGIAKLLDQSATSIPSNTVQGTIGYMAPENAFTTVKSRE 999 Query: 339 ADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSV 455 +DVYS T K S G+ D+ WV+SV Sbjct: 1000 SDVYSYGVVLLELITRKKALDPSFNGE--TDIVGWVRSV 1036
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 72.0 bits (175), Expect = 7e-13 Identities = 50/139 (35%), Positives = 75/139 (53%), Gaps = 9/139 (6%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHS--THNLAHG 179 D+++LVY ++ NGSL L+G S R +DW R+ AL A+RGLA+LH+ ++ H Sbjct: 663 DQQILVYPFMSNGSLLDRLYGE-ASKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIHR 721 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAP-------SSTRAGAGGYRAPEVVDTRRPTFK 338 +VKSSN+LL A ++DF +AP S G GY PE T++ + K Sbjct: 722 DVKSSNILLDQSM-CAKVADFGFSK-YAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEK 779 Query: 339 ADVYSXXXXXXXXXTGKSP 395 +DV+S +G+ P Sbjct: 780 SDVFSFGVVLLEIVSGREP 798
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 70.5 bits (171), Expect = 2e-12 Identities = 55/162 (33%), Positives = 82/162 (50%), Gaps = 9/162 (5%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN--LAHG 179 D++LLVY+++P GSL LH + +DW+ RM+ A A++GL LH N + + Sbjct: 154 DQRLLVYEFMPLGSLEDHLH-DLPPDKEALDWNMRMKIAAGAAKGLEFLHDKANPPVIYR 212 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPS------STRA-GAGGYRAPEVVDTRRPTFK 338 + KSSN+LL + LSDF L + P+ STR G GY APE T + T K Sbjct: 213 DFKSSNILLDEGFH-PKLSDFGLAKL-GPTGDKSHVSTRVMGTYGYCAPEYAMTGQLTVK 270 Query: 339 ADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 +DVYS TG+ + + G +L W + + + Sbjct: 271 SDVYSFGVVFLELITGRKAIDSEMP-HGEQNLVAWARPLFND 311
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 70.5 bits (171), Expect = 2e-12 Identities = 50/140 (35%), Positives = 76/140 (54%), Gaps = 10/140 (7%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHS--THNLAHG 179 D+++LVY ++ NGSL L+G R +DW R+ AL A+RGLA+LH+ ++ H Sbjct: 662 DQQILVYPFMSNGSLLDRLYGEPAK-RKILDWPTRLSIALGAARGLAYLHTFPGRSVIHR 720 Query: 180 NVKSSNVLLRLDYD-AAALSDFCLHPIFAP-------SSTRAGAGGYRAPEVVDTRRPTF 335 +VKSSN+L LD+ A ++DF +AP S G GY PE T++ + Sbjct: 721 DVKSSNIL--LDHSMCAKVADFGFSK-YAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSE 777 Query: 336 KADVYSXXXXXXXXXTGKSP 395 K+DV+S +G+ P Sbjct: 778 KSDVFSFGVVLLEIVSGREP 797
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 69.3 bits (168), Expect = 5e-12 Identities = 52/155 (33%), Positives = 78/155 (50%), Gaps = 8/155 (5%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHS-THNLAHGNV 185 E LLVY+++P GSL + L P WD R++ + A+RGLA LHS + + + Sbjct: 164 ELLLVYEFMPKGSLESHLFRRND----PFPWDLRIKIVIGAARGLAFLHSLQREVIYRDF 219 Query: 186 KSSNVLLRLDYDAAALSDFCLHPIFAPSSTRA-------GAGGYRAPEVVDTRRPTFKAD 344 K+SN+LL +YD A LSDF L + P+ ++ G GY APE + T K+D Sbjct: 220 KASNILLDSNYD-AKLSDFGLAKL-GPADEKSHVTTRIMGTYGYAAPEYMATGHLYVKSD 277 Query: 345 VYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQ 449 V++ TG + H + G L W++ Sbjct: 278 VFAFGVVLLEIMTGLT-AHNTKRPRGQESLVDWLR 311
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 67.0 bits (162), Expect = 2e-11 Identities = 47/144 (32%), Positives = 74/144 (51%), Gaps = 9/144 (6%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH--STHNLAHGN 182 E+LLVY+++ +GSL LHG + + ++W R+ A+ A+RG+ +LH + + H + Sbjct: 575 ERLLVYEFMAHGSLYQHLHGKDPNLKKRLNWARRVTIAVQAARGIEYLHGYACPPVIHRD 634 Query: 183 VKSSNVLLRLDYDAAALSDFCLHPIFAP-------SSTRAGAGGYRAPEVVDTRRPTFKA 341 +KSSN+L+ D++ A ++DF L I P S AG GY PE T K+ Sbjct: 635 IKSSNILIDEDHN-ARVADFGL-SILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKS 692 Query: 342 DVYSXXXXXXXXXTGKSPTHASLE 413 DVYS +G+ E Sbjct: 693 DVYSFGVVLLEILSGRKAIDMQFE 716
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 65.1 bits (157), Expect = 9e-11 Identities = 50/154 (32%), Positives = 72/154 (46%), Gaps = 6/154 (3%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 D LVY Y+PNGSL L S G P+ W R + A + G+ LH H++ H ++ Sbjct: 256 DNLCLVYAYMPNGSLLDRL--SCLDGTPPLSWHTRCKVAQGTANGIRFLHENHHI-HRDI 312 Query: 186 KSSNVLLRLDYDAAALSDFCLHPIFA------PSSTRAGAGGYRAPEVVDTRRPTFKADV 347 KS+N+LL D+ A +SDF L A +S G Y APE + T K+D+ Sbjct: 313 KSANILLDKDF-TAKISDFGLARASARLAQTVMTSRIVGTTAYMAPEAL-RGEITPKSDI 370 Query: 348 YSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQ 449 YS TG + + E LD+ ++ Sbjct: 371 YSFGVVLLELITGLAAVDENREPQLLLDIKEEIE 404
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 61.2 bits (147), Expect = 1e-09 Identities = 43/133 (32%), Positives = 69/133 (51%), Gaps = 8/133 (6%) Frame = +3 Query: 15 LLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN--LAHGNVK 188 +L+Y+Y+ N +L L G R + W+ R++ +L A++GL +LH+ + H +VK Sbjct: 643 VLIYEYMANENLGDYLAGKRSF---ILSWEERLKISLDAAQGLEYLHNGCKPPIVHRDVK 699 Query: 189 SSNVLLRLDYDAAALSDFCLHPIFAP------SSTRAGAGGYRAPEVVDTRRPTFKADVY 350 +N+LL A ++DF L F+ S+ AG+ GY PE TR+ K+DVY Sbjct: 700 PTNILLNEKLQAK-MADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMNEKSDVY 758 Query: 351 SXXXXXXXXXTGK 389 S TG+ Sbjct: 759 SLGVVLLEVITGQ 771
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 61.2 bits (147), Expect = 1e-09 Identities = 45/136 (33%), Positives = 68/136 (50%), Gaps = 8/136 (5%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH--STHNLAHG 179 DEK+L+Y+YL N SL + L G + R+ ++W+ R +RGL +LH S + H Sbjct: 595 DEKMLIYEYLENLSLDSYLFGK--TRRSKLNWNERFDITNGVARGLLYLHQDSRFRIIHR 652 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRA------GAGGYRAPEVVDTRRPTFKA 341 ++K SN+LL + +SDF + IF T A G GY +PE + K+ Sbjct: 653 DLKVSNILLDKNM-IPKISDFGMARIFERDETEANTMKVVGTYGYMSPEYAMYGIFSEKS 711 Query: 342 DVYSXXXXXXXXXTGK 389 DV+S +GK Sbjct: 712 DVFSFGVIVLEIVSGK 727
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 60.5 bits (145), Expect = 2e-09 Identities = 51/154 (33%), Positives = 72/154 (46%), Gaps = 6/154 (3%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 D+ LVY Y+PNGSL L S G P+ W R + A A+ G+ LH H++ H ++ Sbjct: 256 DDLCLVYVYMPNGSLLDRL--SCLDGTPPLSWHMRCKIAQGAANGINFLHENHHI-HRDI 312 Query: 186 KSSNVLLRLDYDAAALSDFCL---HPIFAP---SSTRAGAGGYRAPEVVDTRRPTFKADV 347 KS+N+LL + A +SDF L FA +S G Y APE + T K+D+ Sbjct: 313 KSANILLDEAF-TAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEAL-RGEITPKSDI 370 Query: 348 YSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQ 449 YS TG E LD+ ++ Sbjct: 371 YSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIE 404
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 59.3 bits (142), Expect = 5e-09 Identities = 50/158 (31%), Positives = 75/158 (47%), Gaps = 8/158 (5%) Frame = +3 Query: 12 KLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH--STHNLAHGNV 185 +LLV +Y+ NGSL+ +L G +DW+ R AL ++GLA+LH + H +V Sbjct: 602 RLLVSEYVENGSLANILFSE--GGNILLDWEGRFNIALGVAKGLAYLHHECLEWVIHCDV 659 Query: 186 KSSNVLLRLDYDAAALSDFCLHPIFAPSSTR------AGAGGYRAPEVVDTRRPTFKADV 347 K N+LL ++ ++DF L + + G GY APE V + T K DV Sbjct: 660 KPENILLDQAFE-PKITDFGLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSLPITAKVDV 718 Query: 348 YSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVR 461 YS TG T S GT ++ ++ +VR Sbjct: 719 YSYGVVLLELLTG---TRVSELVGGTDEVHSMLRKLVR 753
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 56.2 bits (134), Expect = 4e-08 Identities = 44/125 (35%), Positives = 59/125 (47%), Gaps = 13/125 (10%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-STHNLAHGNVKSS 194 LVY +LPNGSL LH + +P+ W R+ L +R + LH + +L HG++KSS Sbjct: 286 LVYGFLPNGSLEDQLH-LQTQACSPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSS 344 Query: 195 NVLL--RL-----DYDAAALSDFC-----LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFK 338 NVLL RL D+ A S F A +ST G Y E + T R Sbjct: 345 NVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVD 404 Query: 339 ADVYS 353 D +S Sbjct: 405 TDTFS 409
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 54.7 bits (130), Expect = 1e-07 Identities = 43/125 (34%), Positives = 58/125 (46%), Gaps = 13/125 (10%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-STHNLAHGNVKSS 194 LVY +LPNGSL LH + P+ W R+ L +R + LH + +L HG++KSS Sbjct: 286 LVYGFLPNGSLEDRLH-CQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSS 344 Query: 195 NVLL--RL-----DYDAAALSDFC-----LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFK 338 NVLL RL D+ A S F + A + T G Y E + T R Sbjct: 345 NVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVD 404 Query: 339 ADVYS 353 D +S Sbjct: 405 TDTFS 409
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 52.0 bits (123), Expect = 8e-07 Identities = 51/153 (33%), Positives = 68/153 (44%), Gaps = 19/153 (12%) Frame = +3 Query: 9 EKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLA--HG 179 EKL LVY Y+ NG+L L + G+ TP+ W R+ + ++ + +LH+T A G Sbjct: 248 EKLCLVYPYMSNGTLFDRLQCTNGT--TPLSWHVRISVLIGIAKAIQYLHNTQPCAVICG 305 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAP-----SSTRAGAGG------YRAPEVVDTRR 326 NV S+N+LL D L+DF F P SST GG Y E + R Sbjct: 306 NVSSANILLD-DQLQPKLTDFAA-AHFRPNLEQQSSTINMTGGGRKHLWYMPEEYIRQGR 363 Query: 327 PTFKADVYSXXXXXXXXXTG-----KSPTHASL 410 + K DVYS TG P H L Sbjct: 364 LSVKTDVYSFGIVIMEVLTGCKVVLDDPKHVQL 396
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 52.0 bits (123), Expect = 8e-07 Identities = 38/117 (32%), Positives = 60/117 (51%), Gaps = 5/117 (4%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN-LAHGNVKSS 194 +V +YL GSL +LH S R +D R+ A ++G+ +LH+ + + H ++KS Sbjct: 623 IVTEYLSRGSLYRLLHKS--GAREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSP 680 Query: 195 NVLLRLDYDAAALSDFCLHPI----FAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 N+L+ Y + DF L + F S + AG + APEV+ K+DVYS Sbjct: 681 NLLVDKKY-TVKVCDFGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDVYS 736
>BMR1A_HUMAN (P36894) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen) Length = 532 Score = 50.1 bits (118), Expect = 3e-06 Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 20/132 (15%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHS-------THNLAH 176 L+ DY NGSL L + +D A ++ A SA+ GL HLH+ +AH Sbjct: 307 LITDYHENGSLYDFLKCAT------LDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAH 360 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVDTR---- 323 ++KS N+L++ D A + + + P +TR G Y APEV+D Sbjct: 361 RDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEVLDESLNKN 420 Query: 324 --RPTFKADVYS 353 +P AD+YS Sbjct: 421 HFQPYIMADIYS 432
>BMR1A_MOUSE (P36895) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) Length = 532 Score = 49.7 bits (117), Expect = 4e-06 Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 20/132 (15%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHS-------THNLAH 176 L+ DY NGSL L + +D A ++ A SA+ GL HLH+ +AH Sbjct: 307 LITDYHENGSLYDFLKCAT------LDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAH 360 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVDTR---- 323 ++KS N+L++ D A + + + P +TR G Y APEV+D Sbjct: 361 RDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDIPLNTRVGTKRYMAPEVLDESLNKN 420 Query: 324 --RPTFKADVYS 353 +P AD+YS Sbjct: 421 HFQPYIMADIYS 432
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 49.7 bits (117), Expect = 4e-06 Identities = 46/168 (27%), Positives = 66/168 (39%), Gaps = 19/168 (11%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTP-MDWDARMRSALSASRGLAHLHSTHN--LAHGNVK 188 LVY + GSL A L + P + W R +L +RG+ LH+ L HG++K Sbjct: 289 LVYQLMKGGSLEARLRAHKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIK 348 Query: 189 SSNVLLRLDYDAAALSDFCLHPIFA--------PSSTRA--------GAGGYRAPEVVDT 320 +N+LL D CL P P S A G Y PE + Sbjct: 349 PANILL----------DQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNF 398 Query: 321 RRPTFKADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 R+ + DVYS TG+ T E + +L +V+ R+ Sbjct: 399 RQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQ 446
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 49.3 bits (116), Expect = 5e-06 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 2/114 (1%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN-LAHGNVKSS 194 L+ +YL GSL L+G + + +R AL ++ LA+LHS + H ++K Sbjct: 81 LLMEYLEEGSLHNYLYGD---DKWEYTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQ 137 Query: 195 NVLLRLDYDAAALSDFCLHPIFAPSST-RAGAGGYRAPEVVDTRRPTFKADVYS 353 N+LL ++ + DF L + + T G Y APE + + T K DVYS Sbjct: 138 NMLLYNQHEDLKICDFGLATDMSNNKTDMQGTLRYMAPEAIKHLKYTAKCDVYS 191
>TOPK_BRARE (Q6DHU8) T-lymphokine-activated killer cell-originated protein| kinase homolog (EC 2.7.12.2) (PDZ-binding kinase) Length = 339 Score = 48.5 bits (114), Expect = 8e-06 Identities = 35/147 (23%), Positives = 65/147 (44%), Gaps = 7/147 (4%) Frame = +3 Query: 12 KLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKS 191 K L ++ SL+ ++ R G D + AL +RGL +LH+ L HG++KS Sbjct: 114 KCLAMEFGGEQSLNDLIEKRREEGLQAFPVDTIEKVALHVARGLLYLHNEKKLLHGDMKS 173 Query: 192 SNVLLRLDYDAAALSDFCLH-------PIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVY 350 NV+++ D+++ + D + + P + G ++ E ++ T KAD++ Sbjct: 174 CNVVIKGDFESIKICDVGVSLPLDENMQVSDPKAHYIGTEPWKPKEALEDGVITDKADIF 233 Query: 351 SXXXXXXXXXTGKSPTHASLEGDGTLD 431 + T P L+ +G D Sbjct: 234 AYGLTLWEMMTLSVPHLEMLDTEGDED 260
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 48.5 bits (114), Expect = 8e-06 Identities = 38/130 (29%), Positives = 61/130 (46%), Gaps = 4/130 (3%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRG-SGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSS 194 ++ +Y +G L +L R + R +DW + S G+ +LH H + H ++KS Sbjct: 231 IIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIAS------GMNYLH-LHKIIHRDLKSP 283 Query: 195 NVLLRLDYDAAALSDFCLHPIFAPSSTR---AGAGGYRAPEVVDTRRPTFKADVYSXXXX 365 NVL+ DA +SDF + ST+ AG + APEV+ + K D++S Sbjct: 284 NVLVT-HTDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVV 342 Query: 366 XXXXXTGKSP 395 TG+ P Sbjct: 343 LWELLTGEIP 352
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 48.1 bits (113), Expect = 1e-05 Identities = 38/130 (29%), Positives = 61/130 (46%), Gaps = 4/130 (3%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRG-SGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSS 194 ++ +Y +G L +L R + R +DW + S G+ +LH H + H ++KS Sbjct: 231 IIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIAS------GMNYLH-LHKIIHRDLKSP 283 Query: 195 NVLLRLDYDAAALSDFCLHPIFAPSSTR---AGAGGYRAPEVVDTRRPTFKADVYSXXXX 365 NVL+ DA +SDF + ST+ AG + APEV+ + K D++S Sbjct: 284 NVLVT-HTDAVKISDFGTSKELSDKSTKMSFAGTVAWLAPEVIRNEPVSEKVDIWSFGVV 342 Query: 366 XXXXXTGKSP 395 TG+ P Sbjct: 343 LWELLTGEIP 352
>AMHR2_RAT (Q62893) Anti-Muellerian hormone type-2 receptor precursor (EC| 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) (C14) Length = 557 Score = 48.1 bits (113), Expect = 1e-05 Identities = 45/143 (31%), Positives = 58/143 (40%), Gaps = 30/143 (20%) Frame = +3 Query: 15 LLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTH--------NL 170 LLV + P GSL L + DW + +R ALS + GLA LH + Sbjct: 274 LLVLELYPKGSLCHYLT------QYTSDWGSSLRMALSLAEGLAFLHGERWQDGQYKPGI 327 Query: 171 AHGNVKSSNVLLRLDYDAA--------ALSDFCLHPIFAPSSTR-------AGAGGYRAP 305 AH ++ S NVL+R D A L P AP+ R AG Y AP Sbjct: 328 AHRDLSSQNVLIREDRSCAIGDLGLALVLPGLAQPPALAPTQPRGPAAILEAGTQRYMAP 387 Query: 306 EVVDTR-------RPTFKADVYS 353 E++D +ADVYS Sbjct: 388 ELLDKTLDLQDWGTALQRADVYS 410
>TGFR2_RAT (P38438) TGF-beta receptor type-2 precursor (EC 2.7.11.30)| (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor) Length = 567 Score = 47.4 bits (111), Expect = 2e-05 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 22/112 (19%) Frame = +3 Query: 84 RTPMDWDARMRSALSASRGLAHLHSTHN--------LAHGNVKSSNVLLRLDYDAAALSD 239 R + W+ + S +RG+AHLHS H + H ++KSSN+L++ D L D Sbjct: 339 RHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDL-TCCLCD 397 Query: 240 FCLHPIFAP--------SSTRAGAGGYRAPEVVDTR-----RPTFK-ADVYS 353 F L P +S + G Y APEV+++R +FK DVYS Sbjct: 398 FGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENMESFKQTDVYS 449
>TGFR2_HUMAN (P37173) TGF-beta receptor type-2 precursor (EC 2.7.11.30)| (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor) Length = 567 Score = 47.4 bits (111), Expect = 2e-05 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 22/112 (19%) Frame = +3 Query: 84 RTPMDWDARMRSALSASRGLAHLHSTHN--------LAHGNVKSSNVLLRLDYDAAALSD 239 R + W+ + S +RG+AHLHS H + H ++KSSN+L++ D L D Sbjct: 339 RHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDL-TCCLCD 397 Query: 240 FCLHPIFAP--------SSTRAGAGGYRAPEVVDTR-----RPTFK-ADVYS 353 F L P +S + G Y APEV+++R +FK DVYS Sbjct: 398 FGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENAESFKQTDVYS 449
>PKNK_MYCTU (P95078) Probable serine/threonine-protein kinase pknK (EC| 2.7.11.1) Length = 1110 Score = 47.4 bits (111), Expect = 2e-05 Identities = 42/138 (30%), Positives = 59/138 (42%), Gaps = 6/138 (4%) Frame = +3 Query: 18 LVYDYLPNGSLSAML--HGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKS 191 +V Y SL ++ HG P+DW + + + L H L H +VK Sbjct: 101 IVMPYHAKNSLETLIRRHG-------PLDWRETLSIGVKLAGALEAAHRVGTL-HRDVKP 152 Query: 192 SNVLLRLDYDAAALSDFCLHPIFAPSSTR----AGAGGYRAPEVVDTRRPTFKADVYSXX 359 N+LL DY L+DF + I T AG+ + APEV++ PT +DVYS Sbjct: 153 GNILLT-DYGEPQLTDFGIARIAGGFETATGVIAGSPAFTAPEVLEGASPTPASDVYSLG 211 Query: 360 XXXXXXXTGKSPTHASLE 413 TG HA+ E Sbjct: 212 ATLFCALTG----HAAYE 225
>TGFR2_MOUSE (Q62312) TGF-beta receptor type-2 precursor (EC 2.7.11.30)| (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor) Length = 592 Score = 47.4 bits (111), Expect = 2e-05 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 22/112 (19%) Frame = +3 Query: 84 RTPMDWDARMRSALSASRGLAHLHSTHN--------LAHGNVKSSNVLLRLDYDAAALSD 239 R + W+ + S +RG+AHLHS H + H ++KSSN+L++ D L D Sbjct: 364 RHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDL-TCCLCD 422 Query: 240 FCLHPIFAP--------SSTRAGAGGYRAPEVVDTRR-----PTFK-ADVYS 353 F L P +S + G Y APEV+++R +FK DVYS Sbjct: 423 FGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYS 474
>CLA4_ASHGO (Q9HFW2) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 793 Score = 47.4 bits (111), Expect = 2e-05 Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 6/137 (4%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGS--GRTPMDWDARMRSALSASRGLAHLHSTHNLAH 176 +D+ +V +Y+ GSL+ ++ S GS +PM +GL LH H + H Sbjct: 584 EDDLWVVMEYMEGGSLTDVIENSIGSDASESPMTEPQIAYIVRETCQGLKFLHDKH-IIH 642 Query: 177 GNVKSSNVLLRLDYDAAALSDF--C--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKAD 344 ++KS NVLL + ++DF C L + +T G + APEVV R K D Sbjct: 643 RDIKSDNVLLDT-HGRVKITDFGFCAKLTDKRSKRATMVGTPYWMAPEVVKQREYDEKVD 701 Query: 345 VYSXXXXXXXXXTGKSP 395 V+S G+ P Sbjct: 702 VWSLGIMTIEMLEGEPP 718
>PKNK_MYCBO (Q7TXA9) Probable serine/threonine-protein kinase pknK (EC| 2.7.11.1) Length = 1110 Score = 47.0 bits (110), Expect = 2e-05 Identities = 42/138 (30%), Positives = 59/138 (42%), Gaps = 6/138 (4%) Frame = +3 Query: 18 LVYDYLPNGSLSAML--HGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKS 191 +V Y SL ++ HG P+DW + + + L H L H +VK Sbjct: 101 IVMPYHAKNSLETLIRRHG-------PLDWRETLSIGVKLAGALEAAHRVGTL-HRDVKP 152 Query: 192 SNVLLRLDYDAAALSDFCLHPIFAPSSTR----AGAGGYRAPEVVDTRRPTFKADVYSXX 359 N+LL DY L+DF + I T AG+ + APEV++ PT +DVYS Sbjct: 153 GNILLT-DYGEPQLTDFGIARIAGGFETATGVIAGSPAFTAPEVLEGASPTPASDVYSLG 211 Query: 360 XXXXXXXTGKSPTHASLE 413 TG HA+ E Sbjct: 212 ATLFCVLTG----HAAYE 225
>TOPK_HUMAN (Q96KB5) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3) Length = 322 Score = 46.6 bits (109), Expect = 3e-05 Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 8/142 (5%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 L +Y SL+ ++ + + P ++ AL+ +RGL +LH L HG++KSSN Sbjct: 113 LAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSN 172 Query: 198 VLLRLDYDAAALSDFCLH-------PIFAPSSTRAGAGGYRAPEVVDTRRP-TFKADVYS 353 V+++ D++ + D + + P + G ++ E V+ T KAD+++ Sbjct: 173 VVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVITDKADIFA 232 Query: 354 XXXXXXXXXTGKSPTHASLEGD 419 T P H +L D Sbjct: 233 FGLTLWEMMTLSIP-HINLSND 253
>PK1_NPVLD (P41720) Serine/threonine-protein kinase 1 (EC 2.7.11.1)| Length = 274 Score = 46.2 bits (108), Expect = 4e-05 Identities = 43/148 (29%), Positives = 62/148 (41%), Gaps = 6/148 (4%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRS------ALSASRGLAHLHSTHNL 170 E LLV DY+P+G L + M + R+R A L LH HN+ Sbjct: 82 EHLLVMDYIPDGDLFDL-----------MQTEPRLREPEISLIAYQLIDALQALHK-HNV 129 Query: 171 AHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVY 350 H +VK NVL R ++ + D+ L I ST G Y +PE ++ D + Sbjct: 130 VHNDVKLENVLYR-RFEQIYVCDYGLCKIAGSPSTFEGTVDYFSPEKINKHAAAVHFDWW 188 Query: 351 SXXXXXXXXXTGKSPTHASLEGDGTLDL 434 + TGK P L+ D +LD+ Sbjct: 189 AVGVLLYEISTGKHP--FKLDQDESLDV 214
>STE11_YEAST (P23561) Serine/threonine-protein kinase STE11 (EC 2.7.11.1)| Length = 738 Score = 46.2 bits (108), Expect = 4e-05 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 7/130 (5%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +Y+P GS+S+ML+ P + G+A+LH N+ H ++K +N+L+ Sbjct: 555 EYVPGGSVSSMLNNYG-----PFEESLITNFTRQILIGVAYLHKK-NIIHRDIKGANILI 608 Query: 207 RLDYDAAALSDFC----LHPIFAPSSTRAGAGG---YRAPEVVDTRRPTFKADVYSXXXX 365 + ++DF L P+ + RA G + +PEVV T KAD++S Sbjct: 609 DIK-GCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCV 667 Query: 366 XXXXXTGKSP 395 TGK P Sbjct: 668 VIEMFTGKHP 677
>TAOK2_RAT (Q9JLS3) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1235 Score = 45.8 bits (107), Expect = 5e-05 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LHS HN+ H +VK+ N+LL + L DF I AP+++ G + APE Sbjct: 135 ALQGLAYLHS-HNMIHRDVKAGNILLS-EPGLVKLGDFGSASIMAPANSFVGTPYWMAPE 192 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K DV+S Sbjct: 193 VILAMDEGQYDGKVDVWS 210
>TAOK2_HUMAN (Q9UL54) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C) Length = 1235 Score = 45.8 bits (107), Expect = 5e-05 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LHS HN+ H +VK+ N+LL + L DF I AP+++ G + APE Sbjct: 135 ALQGLAYLHS-HNMIHRDVKAGNILLS-EPGLVKLGDFGSASIMAPANSFVGTPYWMAPE 192 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K DV+S Sbjct: 193 VILAMDEGQYDGKVDVWS 210
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 45.8 bits (107), Expect = 5e-05 Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 1/132 (0%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVK 188 E ++ +Y NGSL ++ SR S T + + GL +LH + H ++K Sbjct: 94 ELYILLEYCANGSLRRLI--SRSS--TGLSENESKTYVTQTLLGLKYLHG-EGVIHRDIK 148 Query: 189 SSNVLLRLDYDAAALSDFCLHPIFAPSS-TRAGAGGYRAPEVVDTRRPTFKADVYSXXXX 365 ++N+LL D + L+DF + I S+ T AG + APE++ R + +D++S Sbjct: 149 AANILLSAD-NTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGAT 207 Query: 366 XXXXXTGKSPTH 401 T P H Sbjct: 208 VVEMLTKNPPYH 219
>GUC2C_PIG (P55204) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1073 Score = 45.8 bits (107), Expect = 5e-05 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 1/112 (0%) Frame = +3 Query: 21 VYDYLPNGSLSAMLHGSRG-SGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 V +Y GSL +L+ + T MDW+ ++ ++G+++LHS+ HG +KS+N Sbjct: 560 VIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSSKTEVHGRLKSTN 619 Query: 198 VLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 ++ ++DF + I AP + APE + + K DVYS Sbjct: 620 CVVD-SRMVVKITDFGCNSILAPKKDL-----WTAPEHLRRASVSQKGDVYS 665
>TAOK2_MOUSE (Q6ZQ29) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1055 Score = 45.8 bits (107), Expect = 5e-05 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LHS HN+ H +VK+ N+LL + L DF I AP+++ G + APE Sbjct: 135 ALQGLAYLHS-HNMIHRDVKAGNILLS-EPGLVKLGDFGSASIMAPANSFVGTPYWMAPE 192 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K DV+S Sbjct: 193 VILAMDEGQYDGKVDVWS 210
>SHK1_SCHPO (P50527) Serine/threonine-protein kinase pak1/shk1 (EC 2.7.11.1)| Length = 658 Score = 45.4 bits (106), Expect = 7e-05 Identities = 39/136 (28%), Positives = 63/136 (46%), Gaps = 5/136 (3%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSAS-RGLAHLHSTHNLAHG 179 K E +V +Y+ GSL+ ++ + S + ++ + + GL HLH + + H Sbjct: 453 KSELWMVMEYMRGGSLTEVVTNNTLS-------EGQIAAICKETLEGLQHLHE-NGIVHR 504 Query: 180 NVKSSNVLLRLDYDAAALSDF--C--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADV 347 ++KS N+LL L D L+DF C + +T G + APEVV + FK DV Sbjct: 505 DIKSDNILLSLQGDIK-LTDFGFCAQIDSNMTKRTTMVGTPYWMAPEVVTRKEYGFKVDV 563 Query: 348 YSXXXXXXXXXTGKSP 395 +S G+ P Sbjct: 564 WSLGIMAIEMVEGEPP 579
>TOPK_MOUSE (Q9JJ78) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) Length = 330 Score = 45.4 bits (106), Expect = 7e-05 Identities = 23/74 (31%), Positives = 39/74 (52%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 L +Y SL+ ++ +P +R AL +RGL +LH L HG++KSSN Sbjct: 112 LAMEYGGEKSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQEKKLLHGDIKSSN 171 Query: 198 VLLRLDYDAAALSD 239 V+++ D++ + D Sbjct: 172 VVIKGDFETIKICD 185
>BMPR2_MOUSE (O35607) Bone morphogenetic protein receptor type-2 precursor (EC| 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3) Length = 1038 Score = 45.4 bits (106), Expect = 7e-05 Identities = 42/125 (33%), Positives = 59/125 (47%), Gaps = 22/125 (17%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAML--HGSRGSGRTPMDWDARMRSALSASRGLAHLHS-------- 158 E LLV +Y PNGSL L H S DW + R A S +RGLA+LH+ Sbjct: 274 EYLLVMEYYPNGSLCKYLSLHTS--------DWVSSCRLAHSVTRGLAYLHTELPRGDHY 325 Query: 159 THNLAHGNVKSSNVLLRLDYDAAALSDFCL------HPIFAPSS------TRAGAGGYRA 302 ++H ++ S NVL++ D A +SDF L + + P + G Y A Sbjct: 326 KPAISHRDLNSRNVLVKND-GACVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMA 384 Query: 303 PEVVD 317 PEV++ Sbjct: 385 PEVLE 389
>RIPK2_HUMAN (O43353) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containi Length = 540 Score = 45.4 bits (106), Expect = 7e-05 Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 13/139 (9%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHS-THNLAHGNVKSS 194 +V +Y+PNGSL+ +LH R + + W R R + G+ +LH+ T L H ++K+ Sbjct: 93 IVTEYMPNGSLNELLH--RKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQ 150 Query: 195 NVLLRLDYDAAALSDFCLHP------IFAPSSTRAGAGG---YRAPEVVD---TRRPTFK 338 N+LL ++ ++DF L + SS A GG Y PE + R + K Sbjct: 151 NILLDNEFH-VKIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYMPPENYEPGQKSRASIK 209 Query: 339 ADVYSXXXXXXXXXTGKSP 395 D+YS + K P Sbjct: 210 HDIYSYAVITWEVLSRKQP 228
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 45.4 bits (106), Expect = 7e-05 Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 3/115 (2%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 ++ +Y+ G+L L+ + + +R AL SRG+ +LHS + H ++KS+N Sbjct: 162 IITEYMSQGNLRMYLNKKEPYS---LSIETVLRLALDISRGMEYLHS-QGVIHRDLKSNN 217 Query: 198 VLLRLDYDAAALSDF---CLHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 +LL D ++DF CL + G + APE++ + T K DVYS Sbjct: 218 LLLN-DEMRVKVADFGTSCLETQCREAKGNMGTYRWMAPEMIKEKPYTRKVDVYS 271
>TAOK2_XENLA (Q6GPK9) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1025 Score = 45.4 bits (106), Expect = 7e-05 Identities = 32/92 (34%), Positives = 47/92 (51%), Gaps = 3/92 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LH+ HN+ H +VK+ N+LL + L DF I AP+++ G + APE Sbjct: 135 ALQGLAYLHN-HNMIHRDVKAGNILL-TEPGLVKLGDFGSASIMAPANSFVGTPYWMAPE 192 Query: 309 VV---DTRRPTFKADVYSXXXXXXXXXTGKSP 395 V+ D + K DV+S K P Sbjct: 193 VILAMDEGQYDGKVDVWSLGITSIELAERKPP 224
>ACV1B_RAT (P80202) Activin receptor type 1B precursor (EC 2.7.11.30)| (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) Length = 505 Score = 45.1 bits (105), Expect = 9e-05 Identities = 37/114 (32%), Positives = 52/114 (45%), Gaps = 14/114 (12%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 LV DY +GSL L+ R + + ++ ALSA+ GLAHLH +AH Sbjct: 280 LVSDYHEHGSLFDYLN------RYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAH 333 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVD 317 ++KS N+L++ D A D I + R G Y APEV+D Sbjct: 334 RDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLD 387
>ACV1B_MOUSE (Q61271) Activin receptor type 1B precursor (EC 2.7.11.30)| (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) Length = 505 Score = 45.1 bits (105), Expect = 9e-05 Identities = 37/114 (32%), Positives = 52/114 (45%), Gaps = 14/114 (12%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 LV DY +GSL L+ R + + ++ ALSA+ GLAHLH +AH Sbjct: 280 LVSDYHEHGSLFDYLN------RYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAH 333 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVD 317 ++KS N+L++ D A D I + R G Y APEV+D Sbjct: 334 RDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLD 387
>ACV1B_HUMAN (P36896) Activin receptor type 1B precursor (EC 2.7.11.30)| (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) (Activin receptor-like kinase 4) (ALK-4) Length = 505 Score = 45.1 bits (105), Expect = 9e-05 Identities = 37/114 (32%), Positives = 52/114 (45%), Gaps = 14/114 (12%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 LV DY +GSL L+ R + + ++ ALSA+ GLAHLH +AH Sbjct: 280 LVSDYHEHGSLFDYLN------RYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAH 333 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVD 317 ++KS N+L++ D A D I + R G Y APEV+D Sbjct: 334 RDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLD 387
>ACV1C_HUMAN (Q8NER5) Activin receptor type 1C precursor (EC 2.7.11.30)| (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7) Length = 493 Score = 45.1 bits (105), Expect = 9e-05 Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 20/132 (15%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 LV +Y GSL L+ R + ++ ALS + GLAHLH +AH Sbjct: 268 LVSEYHEQGSLYDYLN------RNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAH 321 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVDTRR--- 326 ++KS N+L++ D A D L+ I P + + G Y APE++D Sbjct: 322 RDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVN 381 Query: 327 --PTFK-ADVYS 353 +FK AD+YS Sbjct: 382 IFESFKRADIYS 393
>TAO1B_XENLA (Q7ZYJ0) Serine/threonine-protein kinase TAO1-B (EC 2.7.11.1)| (Thousand and one amino acid protein 1-B) Length = 1001 Score = 45.1 bits (105), Expect = 9e-05 Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LHS HNL H ++K+ N+LL + L+DF I +P+++ G + APE Sbjct: 135 ALQGLAYLHS-HNLIHRDIKAGNILL-TEPGQVKLADFGSASIVSPANSFVGTPYWMAPE 192 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K DV+S Sbjct: 193 VILAMDEGQYDGKVDVWS 210
>TAO1A_XENLA (Q6NU21) Serine/threonine-protein kinase TAO1-A (EC 2.7.11.1)| (Thousand and one amino acid protein 1-A) Length = 1001 Score = 44.7 bits (104), Expect = 1e-04 Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LHS HNL H ++K+ N+LL + L+DF I +P+++ G + APE Sbjct: 135 ALQGLAYLHS-HNLIHRDIKAGNILL-TEPGQVKLADFGSASIASPANSFVGTPYWMAPE 192 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K DV+S Sbjct: 193 VILAMDEGQYDGKVDVWS 210
>M3K14_HUMAN (Q99558) Mitogen-activated protein kinase kinase kinase 14 (EC| 2.7.11.25) (NF-kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK) Length = 947 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/84 (41%), Positives = 41/84 (48%), Gaps = 9/84 (10%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDF----CLHPIFAPSSTRA----- 281 A GL +LHS + HG+VK+ NVLL D AAL DF CL P S Sbjct: 499 ALEGLEYLHS-RRILHGDVKADNVLLSSDGSHAALCDFGHAVCLQPDGLGKSLLTGDYIP 557 Query: 282 GAGGYRAPEVVDTRRPTFKADVYS 353 G + APEVV R K DV+S Sbjct: 558 GTETHMAPEVVLGRSCDAKVDVWS 581
>ACV1C_RAT (P70539) Activin receptor type 1C precursor (EC 2.7.11.30)| (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7) Length = 493 Score = 44.3 bits (103), Expect = 2e-04 Identities = 40/132 (30%), Positives = 60/132 (45%), Gaps = 20/132 (15%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 LV +Y GSL L+ R + ++ ALS + GLAHLH +AH Sbjct: 268 LVSEYHEQGSLYDYLN------RNIVTVAGMVKLALSIASGLAHLHMEIVGTQGKPAIAH 321 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVDTRR--- 326 ++KS N+L++ D A D ++ I P + + G Y APE++D Sbjct: 322 RDIKSKNILVKKCDTCAIADLGLAVKHDSIMNTIDIPQNPKVGTKRYMAPEMLDDTMNVN 381 Query: 327 --PTFK-ADVYS 353 +FK AD+YS Sbjct: 382 IFESFKRADIYS 393
>ACV1C_MOUSE (Q8K348) Activin receptor type 1C precursor (EC 2.7.11.30)| (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7) Length = 493 Score = 44.3 bits (103), Expect = 2e-04 Identities = 40/132 (30%), Positives = 60/132 (45%), Gaps = 20/132 (15%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 LV +Y GSL L+ R + ++ ALS + GLAHLH +AH Sbjct: 268 LVSEYHEQGSLYDYLN------RNIVTVAGMVKLALSIASGLAHLHMEIVGTQGKPAIAH 321 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVDTRR--- 326 ++KS N+L++ D A D ++ I P + + G Y APE++D Sbjct: 322 RDIKSKNILVKKCDTCAIADLGLAVKHDSIMNTIDIPQNPKVGTKRYMAPEMLDDTMNLS 381 Query: 327 --PTFK-ADVYS 353 +FK AD+YS Sbjct: 382 IFESFKRADIYS 393
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 44.3 bits (103), Expect = 2e-04 Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 6/132 (4%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTP---MDWDARMRSALSASRGLAHLHSTHNLAHGNVK 188 ++ ++ G L +L R TP +DW ++ + G+ +LH H + H ++K Sbjct: 221 ILMEFCAQGQLYEVLRAGRPV--TPSLLVDW------SMGIAGGMNYLH-LHKIIHRDLK 271 Query: 189 SSNVLLRLDYDAAALSDFCLHPIFAPSSTR---AGAGGYRAPEVVDTRRPTFKADVYSXX 359 S N+L+ D D +SDF + ST+ AG + APEV+ + K D++S Sbjct: 272 SPNMLITYD-DVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFG 330 Query: 360 XXXXXXXTGKSP 395 TG+ P Sbjct: 331 VVLWELLTGEIP 342
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 44.3 bits (103), Expect = 2e-04 Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 6/132 (4%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTP---MDWDARMRSALSASRGLAHLHSTHNLAHGNVK 188 ++ ++ G L +L R TP +DW ++ + G+ +LH H + H ++K Sbjct: 221 ILMEFCAQGQLYEVLRAGRPV--TPSLLVDW------SMGIAGGMNYLH-LHKIIHRDLK 271 Query: 189 SSNVLLRLDYDAAALSDFCLHPIFAPSSTR---AGAGGYRAPEVVDTRRPTFKADVYSXX 359 S N+L+ D D +SDF + ST+ AG + APEV+ + K D++S Sbjct: 272 SPNMLITYD-DVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFG 330 Query: 360 XXXXXXXTGKSP 395 TG+ P Sbjct: 331 VVLWELLTGEIP 342
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 44.3 bits (103), Expect = 2e-04 Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 6/132 (4%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTP---MDWDARMRSALSASRGLAHLHSTHNLAHGNVK 188 ++ ++ G L +L R TP +DW ++ + G+ +LH H + H ++K Sbjct: 188 ILMEFCAQGQLYEVLRAGRPV--TPSLLVDW------SMGIAGGMNYLH-LHKIIHRDLK 238 Query: 189 SSNVLLRLDYDAAALSDFCLHPIFAPSSTR---AGAGGYRAPEVVDTRRPTFKADVYSXX 359 S N+L+ D D +SDF + ST+ AG + APEV+ + K D++S Sbjct: 239 SPNMLITYD-DVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFG 297 Query: 360 XXXXXXXTGKSP 395 TG+ P Sbjct: 298 VVLWELLTGEIP 309
>BMR1B_MOUSE (P36898) Bone morphogenetic protein receptor type IB precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6) Length = 502 Score = 44.3 bits (103), Expect = 2e-04 Identities = 42/133 (31%), Positives = 63/133 (47%), Gaps = 21/133 (15%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH----STHN---LAH 176 L+ DY NGSL L T +D + ++ A S+ GL HLH ST +AH Sbjct: 277 LITDYHENGSLYDYLKS------TTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAH 330 Query: 177 GNVKSSNVLLRLDYDAAALSDFCL--------HPIFAPSSTRAGAGGYRAPEVVD--TRR 326 ++KS N+L++ + ++D L + + P +TR G Y PEV+D R Sbjct: 331 RDLKSKNILVKKN-GTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNR 389 Query: 327 PTFK----ADVYS 353 F+ AD+YS Sbjct: 390 NHFQSYIMADMYS 402
>BMR1B_HUMAN (O00238) Bone morphogenetic protein receptor type IB precursor (EC| 2.7.11.30) (CDw293 antigen) Length = 502 Score = 44.3 bits (103), Expect = 2e-04 Identities = 42/133 (31%), Positives = 63/133 (47%), Gaps = 21/133 (15%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH----STHN---LAH 176 L+ DY NGSL L T +D + ++ A S+ GL HLH ST +AH Sbjct: 277 LITDYHENGSLYDYLKS------TTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAH 330 Query: 177 GNVKSSNVLLRLDYDAAALSDFCL--------HPIFAPSSTRAGAGGYRAPEVVD--TRR 326 ++KS N+L++ + ++D L + + P +TR G Y PEV+D R Sbjct: 331 RDLKSKNILVKKN-GTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNR 389 Query: 327 PTFK----ADVYS 353 F+ AD+YS Sbjct: 390 NHFQSYIMADMYS 402
>BMR1B_CHICK (Q05438) Bone morphogenetic protein receptor type IB precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6) (RPK-1) Length = 502 Score = 44.3 bits (103), Expect = 2e-04 Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 21/133 (15%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH----STHN---LAH 176 L+ DY NGSL L T +D ++ A S+ GL HLH ST +AH Sbjct: 277 LITDYHENGSLYDYLKS------TTLDTKGMLKLAYSSVSGLCHLHTGIFSTQGKPAIAH 330 Query: 177 GNVKSSNVLLRLDYDAAALSDFCL--------HPIFAPSSTRAGAGGYRAPEVVD--TRR 326 ++KS N+L++ + ++D L + + P +TR G Y PEV+D R Sbjct: 331 RDLKSKNILVKKN-GTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNR 389 Query: 327 PTFK----ADVYS 353 F+ AD+YS Sbjct: 390 NHFQSYIMADMYS 402
>BMPR2_HUMAN (Q13873) Bone morphogenetic protein receptor type-2 precursor (EC| 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) Length = 1038 Score = 43.9 bits (102), Expect = 2e-04 Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 22/125 (17%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAML--HGSRGSGRTPMDWDARMRSALSASRGLAHLHS-------- 158 E LLV +Y PNGSL L H S DW + R A S +RGLA+LH+ Sbjct: 274 EYLLVMEYYPNGSLCKYLSLHTS--------DWVSSCRLAHSVTRGLAYLHTELPRGDHY 325 Query: 159 THNLAHGNVKSSNVLLRLDYDAAALSDFCL------HPIFAPSS------TRAGAGGYRA 302 ++H ++ S NVL++ D +SDF L + + P + G Y A Sbjct: 326 KPAISHRDLNSRNVLVKND-GTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMA 384 Query: 303 PEVVD 317 PEV++ Sbjct: 385 PEVLE 389
>AMHR2_HUMAN (Q16671) Anti-Muellerian hormone type-2 receptor precursor (EC| 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) Length = 573 Score = 43.9 bits (102), Expect = 2e-04 Identities = 38/124 (30%), Positives = 53/124 (42%), Gaps = 23/124 (18%) Frame = +3 Query: 15 LLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTH--------NL 170 LLV + P GSL L + DW + +R ALS ++GLA LH + Sbjct: 276 LLVLELHPKGSLCHYLT------QYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKPGI 329 Query: 171 AHGNVKSSNVLLRLDYDAA--------ALSDFCLHPIFAPSSTR-------AGAGGYRAP 305 AH ++ S NVL+R D A L P + P+ + AG Y AP Sbjct: 330 AHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYMAP 389 Query: 306 EVVD 317 E++D Sbjct: 390 ELLD 393
>STE7_YEAST (P06784) Serine/threonine-protein kinase STE7 (EC 2.7.12.2)| Length = 515 Score = 43.9 bits (102), Expect = 2e-04 Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 11/164 (6%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHG-----SRGSGRTPMDWDARM---RSALSASRGLAHLHST 161 +E +++ +Y GSL +L RG+ + W + + A GL HL+ Sbjct: 265 NEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQ 324 Query: 162 HNLAHGNVKSSNVLLRLDYDAAALSDFCLHP--IFAPSSTRAGAGGYRAPEVVDTRRPTF 335 + + H ++K SNVL+ L DF + I + + T G Y +PE + + Sbjct: 325 YKIIHRDIKPSNVLIN-SKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSI 383 Query: 336 KADVYSXXXXXXXXXTGKSPTHASLE-GDGTLDLPRWVQSVVRE 464 K DV+S TG+ P + DG LDL +Q +V E Sbjct: 384 KGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDL---LQRIVNE 424
>PAK1_CAEEL (Q17850) Serine/threonine-protein kinase pak-1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK1) (CePAK) Length = 572 Score = 43.9 bits (102), Expect = 2e-04 Identities = 42/140 (30%), Positives = 63/140 (45%), Gaps = 10/140 (7%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSAS------RGLAHLHSTHN 167 DE +V +YL GSL T + + +M + A+ + L LHS H Sbjct: 363 DELWVVMEYLAGGSL------------TDVVTECQMEDGIIAAVCREVLQALEFLHSRH- 409 Query: 168 LAHGNVKSSNVLLRLDYDAAALSDF--C--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTF 335 + H ++KS N+LL +D + L+DF C L P +T G + APEVV ++ Sbjct: 410 VIHRDIKSDNILLGMD-GSVKLTDFGFCAQLSPEQRKRTTMVGTPYWMAPEVVTRKQYGP 468 Query: 336 KADVYSXXXXXXXXXTGKSP 395 K DV+S G+ P Sbjct: 469 KVDVWSLGIMAIEMVEGEPP 488
>GUC2C_HUMAN (P25092) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR) Length = 1073 Score = 43.9 bits (102), Expect = 2e-04 Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 1/112 (0%) Frame = +3 Query: 21 VYDYLPNGSLSAMLHGSRG-SGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 V +Y GSL +L+ + T MDW+ ++ ++G+++LHS+ HG +KS+N Sbjct: 560 VIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSSKTEVHGRLKSTN 619 Query: 198 VLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 ++ ++DF + I P + APE + + K DVYS Sbjct: 620 CVVD-SRMVVKITDFGCNSILPPKKDL-----WTAPEHLRQANISQKGDVYS 665
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 43.5 bits (101), Expect = 3e-04 Identities = 25/62 (40%), Positives = 32/62 (51%) Frame = +3 Query: 21 VYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNV 200 +Y Y+ NGSL L G GS P+ W R+ + +LH + H NVKSSNV Sbjct: 285 IYPYMANGSLQDRLQGQGGS--DPLPWPQRVSICSGLLCAVEYLHGL-EIIHSNVKSSNV 341 Query: 201 LL 206 LL Sbjct: 342 LL 343
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 43.5 bits (101), Expect = 3e-04 Identities = 35/119 (29%), Positives = 58/119 (48%), Gaps = 10/119 (8%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +Y+ G+L +L S P+ W R+ AL +RGL +LHS + H ++ S N L+ Sbjct: 130 EYMNGGTLEQLL-----SSPEPLSWPVRLHLALDIARGLRYLHS-KGVFHRDLTSKNCLV 183 Query: 207 RLDYD--AAALSDFCLH---PIFAPSSTR-----AGAGGYRAPEVVDTRRPTFKADVYS 353 R + A + DF L P++ + + G+ + APEV+ KADV++ Sbjct: 184 RREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFA 242
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 43.5 bits (101), Expect = 3e-04 Identities = 39/131 (29%), Positives = 58/131 (44%), Gaps = 8/131 (6%) Frame = +3 Query: 33 LPNGSLSAMLHGSRGSGRTPMDWDARMRSALSAS--RGLAHLHSTHNLAHGNVKSSNVLL 206 +P GSLS++L G P+ + S + +GL +LH H + H ++K NVL+ Sbjct: 448 VPGGSLSSLLRSVWG----PLKDNESTISFYTRQILQGLGYLHDNH-IVHRDIKGDNVLI 502 Query: 207 RLDYDAAALSDF----CLHPIFAPSSTRAGAGGYRAPEVVD--TRRPTFKADVYSXXXXX 368 +SDF L I + T G Y APE++D R AD++S Sbjct: 503 NTFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTV 562 Query: 369 XXXXTGKSPTH 401 TG+ P H Sbjct: 563 IEMATGRPPFH 573
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 43.5 bits (101), Expect = 3e-04 Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 DE +V +YL GSL+ ++ T MD + L LHS + + H ++ Sbjct: 338 DELWVVMEYLAGGSLTDVVT------ETCMDEGQIAAVCRECLQALEFLHS-NQVIHRDI 390 Query: 186 KSSNVLLRLDYDAAALSD--FC--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 KS N+LL +D + L+D FC + P + ST G + APEVV + K D++S Sbjct: 391 KSDNILLGMD-GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWS 449 Query: 354 XXXXXXXXXTGKSP 395 G+ P Sbjct: 450 LGIMAIEMIEGEPP 463
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 43.5 bits (101), Expect = 3e-04 Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 DE +V +YL GSL+ ++ T MD + L LHS + + H ++ Sbjct: 338 DELWVVMEYLAGGSLTDVVT------ETCMDEGQIAAVCRECLQALEFLHS-NQVIHRDI 390 Query: 186 KSSNVLLRLDYDAAALSD--FC--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 KS N+LL +D + L+D FC + P + ST G + APEVV + K D++S Sbjct: 391 KSDNILLGMD-GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWS 449 Query: 354 XXXXXXXXXTGKSP 395 G+ P Sbjct: 450 LGIMAIEMIEGEPP 463
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 43.5 bits (101), Expect = 3e-04 Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 DE +V +YL GSL+ ++ T MD + L LHS + + H ++ Sbjct: 337 DELWVVMEYLAGGSLTDVVT------ETCMDEGQIAAVCRECLQALEFLHS-NQVIHRDI 389 Query: 186 KSSNVLLRLDYDAAALSD--FC--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 KS N+LL +D + L+D FC + P + ST G + APEVV + K D++S Sbjct: 390 KSDNILLGMD-GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWS 448 Query: 354 XXXXXXXXXTGKSP 395 G+ P Sbjct: 449 LGIMAIEMIEGEPP 462
>M3K14_MOUSE (Q9WUL6) Mitogen-activated protein kinase kinase kinase 14 (EC| 2.7.11.25) (NF-kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) Length = 942 Score = 43.5 bits (101), Expect = 3e-04 Identities = 33/84 (39%), Positives = 41/84 (48%), Gaps = 9/84 (10%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDF----CLHPIFAPSSTRA----- 281 A GL +LH T + HG+VK+ NVLL D AAL DF CL P S Sbjct: 501 ALEGLEYLH-TRRILHGDVKADNVLLSSDGSRAALCDFGHALCLQPDGLGKSLLTGDYIP 559 Query: 282 GAGGYRAPEVVDTRRPTFKADVYS 353 G + APEVV + K D++S Sbjct: 560 GTETHMAPEVVMGKPCDAKVDIWS 583
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 43.5 bits (101), Expect = 3e-04 Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 4/135 (2%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGS-RGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 KD L+ +Y+ +G L +L R + T + +M S L +LH N+ H Sbjct: 169 KDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQM------SEALLYLHGK-NIIHR 221 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPS---STRAGAGGYRAPEVVDTRRPTFKADVY 350 ++K N+LL + D +SDF + APS ST G Y PE+V +R DV+ Sbjct: 222 DIKPENILLHFN-DTIKISDFGWS-VHAPSNRRSTLCGTMDYLPPEIVQSRPYDKNVDVW 279 Query: 351 SXXXXXXXXXTGKSP 395 S G P Sbjct: 280 SLGILMYEFLCGAPP 294
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 43.5 bits (101), Expect = 3e-04 Identities = 47/162 (29%), Positives = 68/162 (41%), Gaps = 14/162 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASR---GLAHLHSTHNLA 173 KD V ++L G L ++ + GR + R+ A+ GL LHS + Sbjct: 420 KDHLFFVMEFLNGGDL---MYHIQDKGRFEL-----YRATFYAAEIMCGLQFLHSK-GII 470 Query: 174 HGNVKSSNVLLRLDYDAAALSDF--CLHPIFAPS--STRAGAGGYRAPEVVDTRRPTFKA 341 + ++K NVLL D ++DF C IF S ST G Y APE++ + TF Sbjct: 471 YRDLKLDNVLLDRD-GHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSV 529 Query: 342 DVYSXXXXXXXXXTGKSPTHASLEGD-------GTLDLPRWV 446 D +S G+SP H E + T PRW+ Sbjct: 530 DWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 571
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 43.1 bits (100), Expect = 3e-04 Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 7/133 (5%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRG----SGRTPMDWDARMRSALSASRGLAHLHSTHN--LAHG 179 LV +Y GSL +LHG+ + M W L S+G+A+LHS L H Sbjct: 102 LVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSW------CLQCSQGVAYLHSMQPKALIHR 155 Query: 180 NVKSSNVLLRLDYDAAALSDF-CLHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSX 356 ++K N+LL + DF I + G+ + APEV + + K DV+S Sbjct: 156 DLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSW 215 Query: 357 XXXXXXXXTGKSP 395 T + P Sbjct: 216 GIILWEVITRRKP 228
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 43.1 bits (100), Expect = 3e-04 Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 DE +V +YL GSL+ ++ T MD + L LHS + + H ++ Sbjct: 351 DELWVVMEYLAGGSLTDVVT------ETCMDEGQIAAVCRECLQALDFLHS-NQVIHRDI 403 Query: 186 KSSNVLLRLDYDAAALSD--FC--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 KS N+LL +D + L+D FC + P + ST G + APEVV + K D++S Sbjct: 404 KSDNILLGMD-GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWS 462 Query: 354 XXXXXXXXXTGKSP 395 G+ P Sbjct: 463 LGIMAIEMVEGEPP 476
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 43.1 bits (100), Expect = 3e-04 Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 DE +V +YL GSL+ ++ T MD + L LHS + + H ++ Sbjct: 351 DELWVVMEYLAGGSLTDVVT------ETCMDEGQIAAVCRECLQALDFLHS-NQVIHRDI 403 Query: 186 KSSNVLLRLDYDAAALSD--FC--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 KS N+LL +D + L+D FC + P + ST G + APEVV + K D++S Sbjct: 404 KSDNILLGMD-GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWS 462 Query: 354 XXXXXXXXXTGKSP 395 G+ P Sbjct: 463 LGIMAIEMVEGEPP 476
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 43.1 bits (100), Expect = 3e-04 Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 DE +V +YL GSL+ ++ T MD + L LHS + + H ++ Sbjct: 351 DELWVVMEYLAGGSLTDVVT------ETCMDEGQIAAVCRECLQALDFLHS-NQVIHRDI 403 Query: 186 KSSNVLLRLDYDAAALSD--FC--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 KS N+LL +D + L+D FC + P + ST G + APEVV + K D++S Sbjct: 404 KSDNILLGMD-GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWS 462 Query: 354 XXXXXXXXXTGKSP 395 G+ P Sbjct: 463 LGIMAIEMVEGEPP 476
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 43.1 bits (100), Expect = 3e-04 Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 DE +V +YL GSL+ ++ T MD + L LHS + + H ++ Sbjct: 351 DELWVVMEYLAGGSLTDVVT------ETCMDEGQIAAVCRECLQALDFLHS-NQVIHRDI 403 Query: 186 KSSNVLLRLDYDAAALSD--FC--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 KS N+LL +D + L+D FC + P + ST G + APEVV + K D++S Sbjct: 404 KSDNILLGMD-GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWS 462 Query: 354 XXXXXXXXXTGKSP 395 G+ P Sbjct: 463 LGIMAIEMVEGEPP 476
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 43.1 bits (100), Expect = 3e-04 Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 DE +V +YL GSL+ ++ T MD + L LHS + + H ++ Sbjct: 336 DELWVVMEYLAGGSLTDVVT------ETCMDEGQIAAVCRECLQALDFLHS-NQVIHRDI 388 Query: 186 KSSNVLLRLDYDAAALSD--FC--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 KS N+LL +D + L+D FC + P + ST G + APEVV + K D++S Sbjct: 389 KSDNILLGMD-GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWS 447 Query: 354 XXXXXXXXXTGKSP 395 G+ P Sbjct: 448 LGIMAIEMVEGEPP 461
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 43.1 bits (100), Expect = 3e-04 Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 7/133 (5%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRG----SGRTPMDWDARMRSALSASRGLAHLHSTHN--LAHG 179 LV +Y GSL +LHG+ + M W L S+G+A+LHS L H Sbjct: 102 LVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSW------CLQCSQGVAYLHSMQPKALIHR 155 Query: 180 NVKSSNVLLRLDYDAAALSDF-CLHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSX 356 ++K N+LL + DF I + G+ + APEV + + K DV+S Sbjct: 156 DLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSW 215 Query: 357 XXXXXXXXTGKSP 395 T + P Sbjct: 216 GIILWEVITRRKP 228
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 42.7 bits (99), Expect = 5e-04 Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 7/138 (5%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 +DE L ++ +++P GS+S++L G P + L GL +LH+ H + H Sbjct: 142 EDETLNILLEFVPGGSISSLLEKF---GAFPESVVRTYTNQLLL--GLEYLHN-HAIMHR 195 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYR------APEVVDTRRPTFKA 341 ++K +N+L+ + L+DF A +T +GA + APEV+ +F A Sbjct: 196 DIKGANILVD-NQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFSA 254 Query: 342 DVYSXXXXXXXXXTGKSP 395 D++S TGK+P Sbjct: 255 DIWSVGCTVIEMVTGKAP 272
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 42.7 bits (99), Expect = 5e-04 Identities = 37/137 (27%), Positives = 64/137 (46%), Gaps = 11/137 (8%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH--STHNLAHGNVKS 191 LV +Y G LS L G R ++W A+ +RG+ +LH + + H ++KS Sbjct: 191 LVMEYAAGGPLSRALAGRRVPPHVLVNW------AVQIARGMHYLHCEALVPVIHRDLKS 244 Query: 192 SNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGY--RAPEVVDTRRPTFKAD 344 +N+LL +++ ++DF L + ++ + AG Y APEV+ + +D Sbjct: 245 NNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVIKASTFSKGSD 304 Query: 345 VYSXXXXXXXXXTGKSP 395 V+S TG+ P Sbjct: 305 VWSFGVLLWELLTGEVP 321
>TGFR1_MOUSE (Q64729) TGF-beta receptor type-1 precursor (EC 2.7.11.30)| (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (ESK2) Length = 503 Score = 42.7 bits (99), Expect = 5e-04 Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 14/114 (12%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 LV DY +GSL L+ R + + ++ ALS + GLAHLH +AH Sbjct: 278 LVSDYHEHGSLFDYLN------RYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAH 331 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVD 317 ++KS N+L++ D A D I + R G Y APEV+D Sbjct: 332 RDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLD 385
>TGFR1_HUMAN (P36897) TGF-beta receptor type-1 precursor (EC 2.7.11.30)| (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5) Length = 503 Score = 42.7 bits (99), Expect = 5e-04 Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 14/114 (12%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 LV DY +GSL L+ R + + ++ ALS + GLAHLH +AH Sbjct: 278 LVSDYHEHGSLFDYLN------RYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAH 331 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVD 317 ++KS N+L++ D A D I + R G Y APEV+D Sbjct: 332 RDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLD 385
>MOS_CHICK (P10741) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) Length = 349 Score = 42.7 bits (99), Expect = 5e-04 Identities = 35/130 (26%), Positives = 62/130 (47%), Gaps = 18/130 (13%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSR-----------GSGRTPMDWDARMRSALSASRGLAHLHSTH 164 ++ +Y+ N +L +++G+R G GR + + + GLA LHS Sbjct: 141 IIMEYVGNVTLHHVIYGTRDAWRQGEEEEGGCGRKALSMAEAVCYSCDIVTGLAFLHS-Q 199 Query: 165 NLAHGNVKSSNVLLRLDYDAAALSDF-CLHPIFAPSST------RAGAGGYRAPEVVDTR 323 + H ++K +N+L+ ++ A + DF C + S + G +RAPE++ Sbjct: 200 GIVHLDLKPANILIT-EHGACKIGDFGCSQRLEEGLSQSHHVCQQGGTYTHRAPELLKGE 258 Query: 324 RPTFKADVYS 353 R T KAD+YS Sbjct: 259 RVTAKADIYS 268
>TGFR1_RAT (P80204) TGF-beta receptor type-1 precursor (EC 2.7.11.30)| (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) Length = 501 Score = 42.7 bits (99), Expect = 5e-04 Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 14/114 (12%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 LV DY +GSL L+ R + + ++ ALS + GLAHLH +AH Sbjct: 276 LVSDYHEHGSLFDYLN------RYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAH 329 Query: 177 GNVKSSNVLLR-------LDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVD 317 ++KS N+L++ D A D I + R G Y APEV+D Sbjct: 330 RDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLD 383
>OXSR1_PIG (Q863I2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 529 Score = 42.7 bits (99), Expect = 5e-04 Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 13/146 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHG--SRGSGRTPMDWDARMRSAL-SASRGLAHLHSTHNLA 173 KDE LV L GS+ ++ ++G ++ + +A + + L GL +LH + Sbjct: 85 KDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEATIATILREVLEGLEYLHKNGQI- 143 Query: 174 HGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS---------TRAGAGGYRAPEVVD-TR 323 H +VK+ N+LL D + ++DF + A T G + APEV++ R Sbjct: 144 HRDVKAGNILLGED-GSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVR 202 Query: 324 RPTFKADVYSXXXXXXXXXTGKSPTH 401 FKAD++S TG +P H Sbjct: 203 GYDFKADIWSFGITAIELATGAAPYH 228
>RIPK2_MOUSE (P58801) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 539 Score = 42.7 bits (99), Expect = 5e-04 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 13/139 (9%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTH-NLAHGNVKSS 194 +V +Y+PNGSL+ +LH R + + W R R + G+ +LH+ + L H ++K+ Sbjct: 93 IVTEYMPNGSLNELLH--RKTEYPDIAWPLRFRILHEIALGVNYLHNMNPPLLHHDLKTQ 150 Query: 195 NVLLRLDYDAAALSDFCLHP--IFAPSSTR----AGAGG---YRAPEVVD---TRRPTFK 338 N+LL ++ ++DF L + + S +R A GG Y PE + R + K Sbjct: 151 NILLDNEFH-VKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSRASVK 209 Query: 339 ADVYSXXXXXXXXXTGKSP 395 D+YS + K P Sbjct: 210 HDIYSYAVIMWEVLSRKQP 228
>GRK1_CAEBR (Q622Z7) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 640 Score = 42.7 bits (99), Expect = 5e-04 Identities = 40/134 (29%), Positives = 53/134 (39%), Gaps = 3/134 (2%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGN 182 KD LV + G L L+ G D A + GL HLH H L + + Sbjct: 272 KDALCLVLTLMNGGDLKFHLYNLMPGG---FDEKRVQFYAAEITLGLQHLHLEHIL-YRD 327 Query: 183 VKSSNVLLRLDYDAAALSDFCLHPIFA---PSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 +K N+LL D+ +SD L P R G GY APE+V R T+ D + Sbjct: 328 LKPENILLD-DFGHVRISDLGLAVELKDNEPIKGRVGTVGYMAPEIVKNERYTYGVDWWG 386 Query: 354 XXXXXXXXXTGKSP 395 GK+P Sbjct: 387 VGCLIYEMIEGKAP 400
>AVR2B_PIG (Q66T47) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 512 Score = 42.0 bits (97), Expect = 8e-04 Identities = 40/136 (29%), Positives = 60/136 (44%), Gaps = 21/136 (15%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHST--------- 161 E L+ + GSL+ L G+ + W+ A + SRGL++LH Sbjct: 260 ELWLITAFHDKGSLTDYLKGNI------ITWNELCHVAETMSRGLSYLHEDVPWCRGEGH 313 Query: 162 -HNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSST------RAGAGGYRAPEVVD- 317 ++AH + KS NVLL+ D A L+DF L F P + G Y APEV++ Sbjct: 314 KPSIAHRDFKSKNVLLKSDL-TAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEG 372 Query: 318 ----TRRPTFKADVYS 353 R + D+Y+ Sbjct: 373 AINFQRNAFLRIDMYA 388
>ANPRB_ANGJA (P55202) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1050 Score = 42.0 bits (97), Expect = 8e-04 Identities = 39/127 (30%), Positives = 57/127 (44%), Gaps = 15/127 (11%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 +V +Y P GSL +L + +DW R +G+ LH+++ +HGN+KSSN Sbjct: 598 IVTEYCPRGSLQDILENESIN----LDWMFRYSLINDIVKGMNFLHNSYIGSHGNLKSSN 653 Query: 198 -------VLLRLDYDAAALSDFC----LHPIFAPSSTRAGAGGYRAPE-VVDTRRP---T 332 VL DY A+ C H ++A + APE ++ R P T Sbjct: 654 CVVDSRFVLKITDYGLASFRSSCENEDSHALYAKKL-------WTAPELLIYDRHPPQGT 706 Query: 333 FKADVYS 353 K DVYS Sbjct: 707 QKGDVYS 713
>BYR1_SCHPO (P10506) Protein kinase byr1 (EC 2.7.12.2) (MAPK kinase) (MAPKK)| Length = 340 Score = 42.0 bits (97), Expect = 8e-04 Identities = 40/148 (27%), Positives = 71/148 (47%), Gaps = 4/148 (2%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGN 182 K+ L +Y+ GSL A+L R G P+D ++ +++ +GL +L++ ++ H + Sbjct: 132 KNNISLCMEYMDCGSLDAIL---REGGPIPLDILGKIINSMV--KGLIYLYNVLHIIHRD 186 Query: 183 VKSSNVLLRLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSX 356 +K SNV++ L DF + + + + T G Y +PE + + T K+D++S Sbjct: 187 LKPSNVVVN-SRGEIKLCDFGVSGELVNSVAQTFVGTSTYMSPERIRGGKYTVKSDIWSL 245 Query: 357 XXXXXXXXTGKSPTHASLEGD--GTLDL 434 T + P S D G LDL Sbjct: 246 GISIIELATQELPWSFSNIDDSIGILDL 273
>PBS2_YEAST (P08018) MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B| resistance protein 2) (Suppressor of fluoride sensitivity 4) Length = 668 Score = 42.0 bits (97), Expect = 8e-04 Identities = 33/130 (25%), Positives = 56/130 (43%), Gaps = 7/130 (5%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +Y+ GSL + S G A + +A+ GL L HN+ H +VK +N+L Sbjct: 436 EYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVI--HGLKELKEQHNIIHRDVKPTNILC 493 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRP-----TFKADVYSXXXX 365 + L DF + + + + + T G Y APE + + P T ++D++S Sbjct: 494 SANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLS 553 Query: 366 XXXXXTGKSP 395 G+ P Sbjct: 554 ILEMALGRYP 563
>MOS_PIG (P50118) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 345 Score = 42.0 bits (97), Expect = 8e-04 Identities = 35/140 (25%), Positives = 64/140 (45%), Gaps = 14/140 (10%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRG---------SGRTPMDWDARMRSALSASRGLAHLHSTHNL 170 ++ ++ N +L +++G+ G S ++ + ++ +L GL LHS + Sbjct: 140 IIMEFGGNVTLHQVIYGATGCPEEDGPPCSAGEQLNLEKCLKYSLDVVSGLLFLHS-QGI 198 Query: 171 AHGNVKSSNVLLRLDYDAAALSDF-CLHPI----FAPSSTRAGAGGYRAPEVVDTRRPTF 335 H ++K +N+L+ + D +SDF C + F P G +RAPE++ T Sbjct: 199 VHLDLKPANILIS-EQDVCKISDFGCSERLEDLRFRPRHHLGGTYTHRAPELLKGEPVTP 257 Query: 336 KADVYSXXXXXXXXXTGKSP 395 KAD+YS T + P Sbjct: 258 KADIYSFAITLWQMTTRQVP 277
>OXSR1_PONPY (Q5R495) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 41.6 bits (96), Expect = 0.001 Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 13/146 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHG--SRGSGRTPMDWDARMRSAL-SASRGLAHLHSTHNLA 173 KDE LV L GS+ ++ ++G ++ + ++ + + L GL +LH + Sbjct: 85 KDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQI- 143 Query: 174 HGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS---------TRAGAGGYRAPEVVD-TR 323 H +VK+ N+LL D + ++DF + A T G + APEV++ R Sbjct: 144 HRDVKAGNILLGED-GSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVR 202 Query: 324 RPTFKADVYSXXXXXXXXXTGKSPTH 401 FKAD++S TG +P H Sbjct: 203 GYDFKADIWSFGITAIELATGAAPYH 228
>OXSR1_HUMAN (O95747) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 41.6 bits (96), Expect = 0.001 Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 13/146 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHG--SRGSGRTPMDWDARMRSAL-SASRGLAHLHSTHNLA 173 KDE LV L GS+ ++ ++G ++ + ++ + + L GL +LH + Sbjct: 85 KDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQI- 143 Query: 174 HGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS---------TRAGAGGYRAPEVVD-TR 323 H +VK+ N+LL D + ++DF + A T G + APEV++ R Sbjct: 144 HRDVKAGNILLGED-GSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVR 202 Query: 324 RPTFKADVYSXXXXXXXXXTGKSPTH 401 FKAD++S TG +P H Sbjct: 203 GYDFKADIWSFGITAIELATGAAPYH 228
>AVR2B_RAT (P38445) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 513 Score = 41.6 bits (96), Expect = 0.001 Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 16/119 (13%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHST--------- 161 E L+ + GSL+ L G+ + W+ A + SRGL++LH Sbjct: 261 ELWLITAFHDKGSLTDYLKGNI------ITWNELCHVAETMSRGLSYLHEDVPWCRGEGH 314 Query: 162 -HNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSST------RAGAGGYRAPEVVD 317 ++AH + KS NVLL+ D A L+DF L F P + G Y APEV++ Sbjct: 315 KPSIAHRDFKSKNVLLKSDL-TAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLE 372
>GUC2C_RAT (P23897) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1072 Score = 41.6 bits (96), Expect = 0.001 Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 1/112 (0%) Frame = +3 Query: 21 VYDYLPNGSLSAMLHGSRG-SGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 V +Y GSL +L+ + T MDW+ ++ ++G+++LHS+ HG +KS+N Sbjct: 559 VVEYCERGSLREVLNDTISYPDGTFMDWEFKISVLNDIAKGMSYLHSSKIEVHGRLKSTN 618 Query: 198 VLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 ++ ++DF + I P + APE + + K DVYS Sbjct: 619 CVVD-SRMVVKITDFGCNSILPPKKDL-----WTAPEHLRQATISQKGDVYS 664
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 41.6 bits (96), Expect = 0.001 Identities = 38/137 (27%), Positives = 64/137 (46%), Gaps = 11/137 (8%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTH--NLAHGNVKS 191 LV +Y GSL+ +L +G+ P D + A+ +RG+ +LH+ ++ H ++KS Sbjct: 215 LVMEYARGGSLNRIL-----AGKIPPD--VLVNWAIQIARGMNYLHNEAPMSIIHRDLKS 267 Query: 192 SNVLL-------RLDYDAAALSDFCLHPIFAPSSTRAGAGGY--RAPEVVDTRRPTFKAD 344 SNVL+ L ++DF L + + AG Y PEV+ + +D Sbjct: 268 SNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSAAGTYAWMPPEVISVSTYSKFSD 327 Query: 345 VYSXXXXXXXXXTGKSP 395 V+S TG++P Sbjct: 328 VWSYGVLLWELITGETP 344
>LIMK2_HUMAN (P53671) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 41.6 bits (96), Expect = 0.001 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 KD+KL L+ +Y+ G+L L P W ++R A + G+A+LHS + H Sbjct: 397 KDKKLNLLTEYIEGGTLKDFLRSM-----DPFPWQQKVRFAKGIASGMAYLHSM-CIIHR 450 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRA 281 ++ S N L++LD ++DF L + RA Sbjct: 451 DLNSHNCLIKLD-KTVVVADFGLSRLIVEERKRA 483
>AVR2B_HUMAN (Q13705) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 512 Score = 41.6 bits (96), Expect = 0.001 Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 16/119 (13%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHST--------- 161 E L+ + GSL+ L G+ + W+ A + SRGL++LH Sbjct: 260 ELWLITAFHDKGSLTDYLKGNI------ITWNELCHVAETMSRGLSYLHEDVPWCRGEGH 313 Query: 162 -HNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSST------RAGAGGYRAPEVVD 317 ++AH + KS NVLL+ D A L+DF L F P + G Y APEV++ Sbjct: 314 KPSIAHRDFKSKNVLLKSDL-TAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLE 371
>AVR2B_BOVIN (Q95126) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 512 Score = 41.6 bits (96), Expect = 0.001 Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 16/119 (13%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHST--------- 161 E L+ + GSL+ L G+ + W+ A + SRGL++LH Sbjct: 260 ELWLITAFHDKGSLTDYLKGNI------ITWNELCHVAETMSRGLSYLHEDVPWCRGEGH 313 Query: 162 -HNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSST------RAGAGGYRAPEVVD 317 ++AH + KS NVLL+ D A L+DF L F P + G Y APEV++ Sbjct: 314 KPSIAHRDFKSKNVLLKSDL-TAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLE 371
>AVR2B_MOUSE (P27040) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 536 Score = 41.6 bits (96), Expect = 0.001 Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 16/119 (13%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHST--------- 161 E L+ + GSL+ L G+ + W+ A + SRGL++LH Sbjct: 284 ELWLITAFHDKGSLTDYLKGNI------ITWNELCHVAETMSRGLSYLHEDVPWCRGEGH 337 Query: 162 -HNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSST------RAGAGGYRAPEVVD 317 ++AH + KS NVLL+ D A L+DF L F P + G Y APEV++ Sbjct: 338 KPSIAHRDFKSKNVLLKSDL-TAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLE 395
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 41.2 bits (95), Expect = 0.001 Identities = 34/132 (25%), Positives = 59/132 (44%), Gaps = 6/132 (4%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 ++ +++P GS+S++L P GL +LH+ H + H ++K +N Sbjct: 149 ILLEFVPGGSISSLLEKFG-----PFPESVVRTYTRQLLLGLEYLHN-HAIMHRDIKGAN 202 Query: 198 VLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYR------APEVVDTRRPTFKADVYSXX 359 +L+ + L+DF A +T GA + APEV+ +F AD++S Sbjct: 203 ILVD-NKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFSADIWSVG 261 Query: 360 XXXXXXXTGKSP 395 TGK+P Sbjct: 262 CTVIEMVTGKAP 273
>FUZ7_USTMA (Q99078) Dual specificity protein kinase FUZ7 (EC 2.7.12.2)| Length = 435 Score = 41.2 bits (95), Expect = 0.001 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 2/102 (1%) Frame = +3 Query: 120 ALSASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHP--IFAPSSTRAGAGG 293 A++ S GL +L+ H + H +VK SN+L+ + DF + I + + T G Sbjct: 211 AVAVSHGLTYLYDVHRIIHRDVKPSNILVN-GAGQIKICDFGVSGELINSIADTFVGTST 269 Query: 294 YRAPEVVDTRRPTFKADVYSXXXXXXXXXTGKSPTHASLEGD 419 Y +PE + + + K+DV+S G+ P + E D Sbjct: 270 YMSPERIQGDQYSVKSDVWSLGVSIIDVALGRFPFAENEEDD 311
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 41.2 bits (95), Expect = 0.001 Identities = 28/99 (28%), Positives = 52/99 (52%), Gaps = 3/99 (3%) Frame = +3 Query: 108 RMRSALSASRGLAHLHSTHNL-AHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSST--R 278 +++ A+ G+ +LHS++ + H ++K +N+L+ ++ ++DF I ++T R Sbjct: 1462 KLKLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDEHFNVK-IADFGFARIKEDNTTMTR 1520 Query: 279 AGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 G + APEV+ + KADV+S TGK P Sbjct: 1521 CGTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEP 1559
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 41.2 bits (95), Expect = 0.001 Identities = 33/119 (27%), Positives = 58/119 (48%), Gaps = 10/119 (8%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +Y+ G+L +L S P+ W R+ AL ++GL +LH+ + H ++ S N L+ Sbjct: 125 EYMNGGTLEQLL-----SSPEPLSWPVRLHLALDIAQGLRYLHA-KGVFHRDLTSKNCLV 178 Query: 207 RLDYD--AAALSDFCLH---PIFAPSSTR-----AGAGGYRAPEVVDTRRPTFKADVYS 353 R + A + DF L P++ + + G+ + APEV+ KADV++ Sbjct: 179 RREDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFA 237
>OXSR1_MOUSE (Q6P9R2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 40.8 bits (94), Expect = 0.002 Identities = 40/146 (27%), Positives = 66/146 (45%), Gaps = 13/146 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHG--SRGSGRTPMDWDARMRSAL-SASRGLAHLHSTHNLA 173 KDE LV L GS+ ++ ++G ++ + + + + L GL +LH + Sbjct: 85 KDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKNGQI- 143 Query: 174 HGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS---------TRAGAGGYRAPEVVD-TR 323 H +VK+ N+LL D + ++DF + A T G + APEV++ R Sbjct: 144 HRDVKAGNILLGED-GSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVR 202 Query: 324 RPTFKADVYSXXXXXXXXXTGKSPTH 401 FKAD++S TG +P H Sbjct: 203 GYDFKADIWSFGITAIELATGAAPYH 228
>GRK1_CAEEL (Q09537) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 642 Score = 40.8 bits (94), Expect = 0.002 Identities = 38/134 (28%), Positives = 53/134 (39%), Gaps = 3/134 (2%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGN 182 KD LV + G L L+ G D A + GL HLHS + + + Sbjct: 273 KDALCLVLTLMNGGDLKFHLYNLMPGG---FDEKRVQFYAAEITLGLQHLHS-ERILYRD 328 Query: 183 VKSSNVLLRLDYDAAALSDFCLHPIFA---PSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 +K N+LL D+ +SD L P R G GY APE+V R ++ D + Sbjct: 329 LKPENILLD-DFGHVRISDLGLAVEIKDNEPIKGRVGTVGYMAPEIVKNERYSYGVDWWG 387 Query: 354 XXXXXXXXXTGKSP 395 GK+P Sbjct: 388 VGCLIYEMIEGKAP 401
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 40.8 bits (94), Expect = 0.002 Identities = 37/137 (27%), Positives = 63/137 (45%), Gaps = 11/137 (8%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN--LAHGNVKS 191 LV +Y G+LS +L G R ++W A+ +RG+ +LH+ + H ++KS Sbjct: 172 LVMEYARGGALSRVLAGRRVPPHVLVNW------AVQVARGMNYLHNDAPVPIIHRDLKS 225 Query: 192 SNVLL-------RLDYDAAALSDFCLHPIFAPSSTRAGAGGY--RAPEVVDTRRPTFKAD 344 N+L+ L ++DF L + ++ + AG Y APEV+ + +D Sbjct: 226 INILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSD 285 Query: 345 VYSXXXXXXXXXTGKSP 395 V+S TG+ P Sbjct: 286 VWSFGVLLWELLTGEVP 302
>LIMK2_MOUSE (O54785) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 40.8 bits (94), Expect = 0.002 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 KD+KL L+ +Y+ G+L L P W ++R A S G+A+LHS + H Sbjct: 397 KDKKLNLLTEYIEGGTLKDFLRSV-----DPFPWQQKVRFAKGISSGMAYLHSM-CIIHR 450 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTR 278 ++ S N L++LD ++DF L + R Sbjct: 451 DLNSHNCLIKLD-KTVVVADFGLSRLIVEERKR 482
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/119 (27%), Positives = 58/119 (48%), Gaps = 10/119 (8%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +Y+ G+L +L S P+ W R+ AL ++GL +LH+ + H ++ S N L+ Sbjct: 125 EYMNGGTLEQLL-----SSPEPLSWPVRLHLALDIAQGLRYLHA-KGVFHRDLTSKNCLV 178 Query: 207 RLDYD--AAALSDFCLH---PIFAPSSTR-----AGAGGYRAPEVVDTRRPTFKADVYS 353 R + A + DF L P++ + + G+ + APEV+ KADV++ Sbjct: 179 RREDRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPEVLRGELYDEKADVFA 237
>TAOK3_PONPY (Q5R4F3) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 40.8 bits (94), Expect = 0.002 Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A GLA+LHS H L H ++K+ N+LL + L+DF + +P+++ G + APE Sbjct: 131 ALHGLAYLHS-HALIHRDIKAGNILLT-EPGQVKLADFGSASVASPANSFVGTPYWMAPE 188 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K DV+S Sbjct: 189 VILAMDEGQYDGKVDVWS 206
>AVR2B_XENLA (P27041) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 511 Score = 40.4 bits (93), Expect = 0.002 Identities = 39/119 (32%), Positives = 53/119 (44%), Gaps = 16/119 (13%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHST--------H 164 E L+ + GSL+ L G+ S W+ + +RGLA+LH H Sbjct: 259 ELWLITAFHDKGSLTDYLKGNLVS------WNELCHITETMARGLAYLHEDVPRCKGEGH 312 Query: 165 N--LAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSST------RAGAGGYRAPEVVD 317 +AH + KS NVLLR D A L+DF L F P + G Y APEV++ Sbjct: 313 KPAIAHRDFKSKNVLLRNDL-TAILADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLE 370
>TAOK3_HUMAN (Q9H2K8) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK-inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen H Length = 898 Score = 40.4 bits (93), Expect = 0.002 Identities = 35/124 (28%), Positives = 53/124 (42%), Gaps = 13/124 (10%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A GLA+LHS H L H ++K+ N+LL + L+DF + +P+++ G + APE Sbjct: 131 ALHGLAYLHS-HALIHRDIKAGNILLT-EPGQVKLADFGSASMASPANSFVGTPYWMAPE 188 Query: 309 VV---DTRRPTFKADVYSXXXXXXXXXTGKSPT----------HASLEGDGTLDLPRWVQ 449 V+ D + K D++S K P H + TL W Sbjct: 189 VILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTD 248 Query: 450 SVVR 461 S R Sbjct: 249 SFRR 252
>M3K5_HUMAN (Q99683) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1374 Score = 40.4 bits (93), Expect = 0.002 Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 8/131 (6%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSAS--RGLAHLHSTHNLAHGNVKSSNV 200 + +P GSLSA+L G P+ + + + GL +LH + + H ++K NV Sbjct: 755 EQVPGGSLSALLRSKWG----PLKDNEQTIGFYTKQILEGLKYLHD-NQIVHRDIKGDNV 809 Query: 201 LLRLDYDAAALSDF----CLHPIFAPSSTRAGAGGYRAPEVVD--TRRPTFKADVYSXXX 362 L+ +SDF L I + T G Y APE++D R AD++S Sbjct: 810 LINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGC 869 Query: 363 XXXXXXTGKSP 395 TGK P Sbjct: 870 TIIEMATGKPP 880
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 40.4 bits (93), Expect = 0.002 Identities = 44/147 (29%), Positives = 62/147 (42%), Gaps = 13/147 (8%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSA-------LSASRGLAHLHSTH 164 D L+V ++ +G+L + RGSG DAR L L ++HS H Sbjct: 90 DRLLIVMEFADSGNLDEQIK-LRGSG------DARYFQEHEALFLFLQLCLALDYIHS-H 141 Query: 165 NLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPS------STRAGAGGYRAPEVVDTRR 326 + H ++KS+NVLL L DF + + ST G Y APE+ + +R Sbjct: 142 KMLHRDIKSANVLLT-STGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNKR 200 Query: 327 PTFKADVYSXXXXXXXXXTGKSPTHAS 407 KADV+S K P AS Sbjct: 201 YNKKADVWSLGVLLYEIMGMKKPFSAS 227
>CLA4_CANAL (O14427) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 971 Score = 40.4 bits (93), Expect = 0.002 Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 10/140 (7%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSAS------RGLAHLHSTHN 167 +E ++ +Y+ GSL+ ++ + D ++ A+ +GL HLH H Sbjct: 750 NELWVIMEYMQGGSLTEIIENN----------DFKLNEKQIATICFETLKGLQHLHKKH- 798 Query: 168 LAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPS----STRAGAGGYRAPEVVDTRRPTF 335 + H ++KS NVLL Y ++DF +T G + APEVV + Sbjct: 799 IIHRDIKSDNVLLDA-YGNVKITDFGFCAKLTDQRNKRATMVGTPYWMAPEVVKQKEYDE 857 Query: 336 KADVYSXXXXXXXXXTGKSP 395 K DV+S G+ P Sbjct: 858 KVDVWSLGIMTIEMIEGEPP 877
>STK39_RAT (O88506) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (Pancreatic serine/threonine-protein kinase) (PS/TK) (PSTK1) Length = 553 Score = 40.4 bits (93), Expect = 0.002 Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 13/146 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHG--SRGSGRTPMDWDARMRSALS-ASRGLAHLHSTHNLA 173 KDE LV L GS+ ++ +RG + + +A + + L GL +LH + Sbjct: 140 KDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQI- 198 Query: 174 HGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS---------TRAGAGGYRAPEVVD-TR 323 H ++K+ N+LL D + ++DF + A T G + APEV++ R Sbjct: 199 HRDLKAGNILLGED-GSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVR 257 Query: 324 RPTFKADVYSXXXXXXXXXTGKSPTH 401 FKAD++S TG +P H Sbjct: 258 GYDFKADMWSFGITAIELATGAAPYH 283
>STK39_MOUSE (Q9Z1W9) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) Length = 556 Score = 40.4 bits (93), Expect = 0.002 Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 13/146 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHG--SRGSGRTPMDWDARMRSALS-ASRGLAHLHSTHNLA 173 KDE LV L GS+ ++ +RG + + +A + + L GL +LH + Sbjct: 143 KDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQI- 201 Query: 174 HGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS---------TRAGAGGYRAPEVVD-TR 323 H ++K+ N+LL D + ++DF + A T G + APEV++ R Sbjct: 202 HRDLKAGNILLGED-GSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVR 260 Query: 324 RPTFKADVYSXXXXXXXXXTGKSPTH 401 FKAD++S TG +P H Sbjct: 261 GYDFKADMWSFGITAIELATGAAPYH 286
>MOS_HUMAN (P00540) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 346 Score = 40.4 bits (93), Expect = 0.002 Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 7/102 (6%) Frame = +3 Query: 111 MRSALSASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDF-CLHPIF------APS 269 ++ +L GL LHS ++ H ++K +N+L+ + D +SDF C + PS Sbjct: 179 LKYSLDVVNGLLFLHS-QSIVHLDLKPANILIS-EQDVCKISDFGCSEKLEDLLCFQTPS 236 Query: 270 STRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 G +RAPE++ T KAD+YS T ++P Sbjct: 237 YPLGGTYTHRAPELLKGEGVTPKADIYSFAITLWQMTTKQAP 278
>TAOK1_RAT (O88664) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 40.4 bits (93), Expect = 0.002 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LHS H + H ++K+ N+LL + L+DF + +P+++ G + APE Sbjct: 135 ALQGLAYLHS-HTMIHRDIKAGNILLT-EPGQVKLADFGSASMASPANSFVGTPYWMAPE 192 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K DV+S Sbjct: 193 VILAMDEGQYDGKVDVWS 210
>TAOK1_MOUSE (Q5F2E8) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 40.4 bits (93), Expect = 0.002 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LHS H + H ++K+ N+LL + L+DF + +P+++ G + APE Sbjct: 135 ALQGLAYLHS-HTMIHRDIKAGNILLT-EPGQVKLADFGSASMASPANSFVGTPYWMAPE 192 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K DV+S Sbjct: 193 VILAMDEGQYDGKVDVWS 210
>TAOK1_HUMAN (Q7L7X3) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B) Length = 1001 Score = 40.4 bits (93), Expect = 0.002 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LHS H + H ++K+ N+LL + L+DF + +P+++ G + APE Sbjct: 135 ALQGLAYLHS-HTMIHRDIKAGNILLT-EPGQVKLADFGSASMASPANSFVGTPYWMAPE 192 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K DV+S Sbjct: 193 VILAMDEGQYDGKVDVWS 210
>M3K5_MOUSE (O35099) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1380 Score = 40.4 bits (93), Expect = 0.002 Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 8/131 (6%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSAS--RGLAHLHSTHNLAHGNVKSSNV 200 + +P GSLSA+L G P+ + + + GL +LH + + H ++K NV Sbjct: 762 EQVPGGSLSALLRSKWG----PLKDNEQTIGFYTKQILEGLKYLHD-NQIVHRDIKGDNV 816 Query: 201 LLRLDYDAAALSDF----CLHPIFAPSSTRAGAGGYRAPEVVD--TRRPTFKADVYSXXX 362 L+ +SDF L I + T G Y APE++D R AD++S Sbjct: 817 LINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGC 876 Query: 363 XXXXXXTGKSP 395 TGK P Sbjct: 877 TIIEMATGKPP 887
>TAOK3_XENLA (Q6DD27) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 896 Score = 40.4 bits (93), Expect = 0.002 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LHS HN+ H ++K+ N+LL + L+DF +P+++ G + APE Sbjct: 131 ALQGLAYLHS-HNMIHRDIKAGNILL-TEPGQVKLADFGSASKSSPANSFVGTPYWMAPE 188 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K D++S Sbjct: 189 VILAMDEGQYDGKIDIWS 206
>STK39_HUMAN (Q9UEW8) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT) Length = 547 Score = 40.4 bits (93), Expect = 0.002 Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 13/146 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHG--SRGSGRTPMDWDARMRSALS-ASRGLAHLHSTHNLA 173 KDE LV L GS+ ++ +RG + + +A + + L GL +LH + Sbjct: 133 KDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQI- 191 Query: 174 HGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS---------TRAGAGGYRAPEVVD-TR 323 H ++K+ N+LL D + ++DF + A T G + APEV++ R Sbjct: 192 HRDLKAGNILLGED-GSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVR 250 Query: 324 RPTFKADVYSXXXXXXXXXTGKSPTH 401 FKAD++S TG +P H Sbjct: 251 GYDFKADMWSFGITAIELATGAAPYH 276
>GUC2C_CAVPO (P70106) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (Guanylyl cyclase C) Length = 1076 Score = 40.4 bits (93), Expect = 0.002 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 1/112 (0%) Frame = +3 Query: 21 VYDYLPNGSLSAMLHGSRG-SGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 V +Y GSL +L+ + T M W+ ++ ++G+++LHS+ HG +KS+N Sbjct: 563 VIEYCERGSLREVLNETISYPDGTIMGWEFKISVLYDIAKGMSYLHSSKIEVHGRLKSTN 622 Query: 198 VLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 ++ ++DF + I P + APE + + K DVYS Sbjct: 623 CVVD-SRMVVKITDFGYNSILPPKKDL-----WTAPEHLRQASTSQKGDVYS 668
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 40.4 bits (93), Expect = 0.002 Identities = 39/134 (29%), Positives = 56/134 (41%), Gaps = 3/134 (2%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGN 182 KD LV + G L ++ G ++ AR +A A GL HLH + + + Sbjct: 379 KDALCLVLTIMNGGDLKFHIYNMGGEPGFELE-RARFYAAEVAC-GLQHLHK-QGIVYRD 435 Query: 183 VKSSNVLLRLDYDAAALSDFCLH---PIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYS 353 K N+LL D+ +SD L P R G GY APEV+D + F D +S Sbjct: 436 CKPENILLD-DHGHVRISDLGLAVEIPEGEMVRGRVGTVGYMAPEVIDNEKYAFSPDWFS 494 Query: 354 XXXXXXXXXTGKSP 395 G++P Sbjct: 495 FGCLLYEMIEGQAP 508
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 40.0 bits (92), Expect = 0.003 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 14/162 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASR---GLAHLHSTHNLA 173 KD V ++L G L M H + GR + R+ A+ GL LHS + Sbjct: 418 KDHLFFVMEFLNGGDL--MFH-IQDKGRFEL-----YRATFYAAEIICGLQFLHSK-GII 468 Query: 174 HGNVKSSNVLLRLDYDAAALSDF--CLHPIFAP--SSTRAGAGGYRAPEVVDTRRPTFKA 341 + ++K NV+L D ++DF C IF +ST G Y APE++ + +F Sbjct: 469 YRDLKLDNVMLDRD-GHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSV 527 Query: 342 DVYSXXXXXXXXXTGKSPTHASLEGD-------GTLDLPRWV 446 D +S G+SP H E + T PRW+ Sbjct: 528 DWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 569
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 40.0 bits (92), Expect = 0.003 Identities = 42/161 (26%), Positives = 67/161 (41%), Gaps = 13/161 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHN--LAH 176 KD V ++L G L ++ + GR + R+ A+ + L HN + + Sbjct: 418 KDHLFFVMEFLNGGDL---MYHIQDKGRFEL-----YRATFYAAEIVCGLQFLHNKGIIY 469 Query: 177 GNVKSSNVLLRLDYDAAALSDF--CLHPIFAP--SSTRAGAGGYRAPEVVDTRRPTFKAD 344 ++K NV+L D ++DF C IF +ST G Y APE++ + +F D Sbjct: 470 RDLKLDNVMLDQD-GHIKIADFGMCKENIFGEKQASTFCGTPDYIAPEILQGLKYSFSVD 528 Query: 345 VYSXXXXXXXXXTGKSPTHASLEGD-------GTLDLPRWV 446 +S G+SP H E + T PRW+ Sbjct: 529 WWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 569
>ACVL1_MOUSE (Q61288) Serine/threonine-protein kinase receptor R3 precursor (EC| 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I) Length = 502 Score = 40.0 bits (92), Expect = 0.003 Identities = 36/115 (31%), Positives = 54/115 (46%), Gaps = 15/115 (13%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 L+ Y +GSL L R ++ +R A+SA+ GLAHLH +AH Sbjct: 274 LITHYHEHGSLYDFLQ------RQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAH 327 Query: 177 GNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS--------TRAGAGGYRAPEVVD 317 ++KS NVL++ + ++D L + + SS R G Y APEV+D Sbjct: 328 RDLKSRNVLVKSNLQ-CCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLD 381
>STK24_HUMAN (Q9Y6E0) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 40.0 bits (92), Expect = 0.003 Identities = 39/141 (27%), Positives = 63/141 (44%), Gaps = 5/141 (3%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 KD KL ++ +YL GS +L P+D +GL +LHS + H Sbjct: 103 KDTKLWIIMEYLGGGSALDLLEPG------PLDETQIATILREILKGLDYLHSEKKI-HR 155 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPS----STRAGAGGYRAPEVVDTRRPTFKADV 347 ++K++NVLL ++ L+DF + + +T G + APEV+ KAD+ Sbjct: 156 DIKAANVLLS-EHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADI 214 Query: 348 YSXXXXXXXXXTGKSPTHASL 410 +S G+ P H+ L Sbjct: 215 WSLGITAIELARGE-PPHSEL 234
>ACVL1_RAT (P80203) Serine/threonine-protein kinase receptor R3 precursor (EC| 2.7.11.30) (SKR3) (TGF-B superfamily receptor type I) (TSR-I) Length = 504 Score = 40.0 bits (92), Expect = 0.003 Identities = 36/115 (31%), Positives = 54/115 (46%), Gaps = 15/115 (13%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 L+ Y +GSL L R ++ +R A+SA+ GLAHLH +AH Sbjct: 276 LITHYHEHGSLYDFLQ------RQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAH 329 Query: 177 GNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS--------TRAGAGGYRAPEVVD 317 ++KS NVL++ + ++D L + + SS R G Y APEV+D Sbjct: 330 RDLKSRNVLVKSNLQ-CCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLD 383
>MP2K2_MOUSE (Q63932) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 401 Score = 39.7 bits (91), Expect = 0.004 Identities = 31/125 (24%), Positives = 60/125 (48%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L ++ R P D ++ +++ RGLA+L H + H +VK SN+L+ Sbjct: 148 EHMDGGSLDQVLKEAK---RIPEDILGKV--SIAVLRGLAYLREKHQIMHRDVKPSNILV 202 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++D++S Sbjct: 203 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELA 261 Query: 381 TGKSP 395 G+ P Sbjct: 262 IGRYP 266
>LIMK2_RAT (P53670) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 39.7 bits (91), Expect = 0.004 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 KD+KL L+ +Y+ G+L L P W ++R A + G+A+LHS + H Sbjct: 397 KDKKLNLLTEYIEGGTLKDFLRNV-----DPFPWQQKVRFAKGIASGMAYLHSM-CIIHR 450 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTR 278 ++ S N L++LD ++DF L + R Sbjct: 451 DLNSHNCLIKLD-KTVVVADFGLSRLIVEERKR 482
>CLA4_YEAST (P48562) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 842 Score = 39.7 bits (91), Expect = 0.004 Identities = 39/139 (28%), Positives = 61/139 (43%), Gaps = 9/139 (6%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGS--RGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 D+ +V +++ GSL+ ++ S + +P+ +GL LH H + H Sbjct: 634 DDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKH-IIHR 692 Query: 180 NVKSSNVLLRLDYDAAA---LSDF--C--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFK 338 ++KS NVLL D A ++DF C L + +T G + APEVV R K Sbjct: 693 DIKSDNVLL----DTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEK 748 Query: 339 ADVYSXXXXXXXXXTGKSP 395 DV+S G+ P Sbjct: 749 IDVWSLGIMTIEMLEGEPP 767
>LIMK1_DROME (Q8IR79) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (dLIMK)| Length = 1257 Score = 39.7 bits (91), Expect = 0.004 Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 4/102 (3%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 KD+KL +V +Y+ G L ++H + W R+R A + G+++LHS N+ H Sbjct: 467 KDKKLHMVTEYVAGGCLKELIHDPA----QVLPWPQRVRLARDIACGMSYLHSM-NIIHR 521 Query: 180 NVKSSNVLLRLDYDAAALSDFCL-HPIFAP--SSTRAGAGGY 296 ++ S N L+R D + ++DF L + AP S GGY Sbjct: 522 DLNSMNCLVRED-RSVIVADFGLARSVDAPRLPSGNMTPGGY 562
>WIS1_SCHPO (P33886) Protein kinase wis1 (EC 2.7.12.2) (Protein kinase sty2)| Length = 605 Score = 39.7 bits (91), Expect = 0.004 Identities = 36/132 (27%), Positives = 55/132 (41%), Gaps = 9/132 (6%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +Y+ GS+ + G D R+A + +GL L HN+ H +VK +NVL+ Sbjct: 396 EYMDAGSMDKLYAGGI------KDEGVLARTAYAVVQGLKTLKEEHNIIHRDVKPTNVLV 449 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRP-------TFKADVYSXX 359 + L DF + + + + S T G Y APE + P T +ADV+S Sbjct: 450 NSN-GQVKLCDFGVSGNLVASISKTNIGCQSYMAPERIRVGGPTNGVLTYTVQADVWSLG 508 Query: 360 XXXXXXXTGKSP 395 G P Sbjct: 509 LTILEMALGAYP 520
>MP2K2_RAT (P36506) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 400 Score = 39.7 bits (91), Expect = 0.004 Identities = 31/125 (24%), Positives = 60/125 (48%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L ++ R P D ++ +++ RGLA+L H + H +VK SN+L+ Sbjct: 148 EHMDGGSLDQVLKEAK---RIPEDILGKV--SIAVLRGLAYLREKHQIMHRDVKPSNILV 202 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++D++S Sbjct: 203 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELA 261 Query: 381 TGKSP 395 G+ P Sbjct: 262 IGRYP 266
>MP2K2_HUMAN (P36507) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 400 Score = 39.7 bits (91), Expect = 0.004 Identities = 31/125 (24%), Positives = 60/125 (48%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L ++ R P + ++ +++ RGLA+L H + H +VK SN+L+ Sbjct: 148 EHMDGGSLDQVLKEAK---RIPEEILGKV--SIAVLRGLAYLREKHQIMHRDVKPSNILV 202 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y APE + + ++D++S Sbjct: 203 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELA 261 Query: 381 TGKSP 395 G+ P Sbjct: 262 VGRYP 266
>TAOK3_RAT (Q53UA7) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK-inhibitory kinase) (Axotomy-related gene 357 protein) Length = 898 Score = 39.7 bits (91), Expect = 0.004 Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 13/124 (10%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LH H+L H ++K+ N+LL + L+DF + +P+++ G + APE Sbjct: 131 ALQGLAYLHF-HSLIHRDIKAGNILL-TEPGQVKLADFGSASMASPANSFVGTPYWMAPE 188 Query: 309 VV---DTRRPTFKADVYSXXXXXXXXXTGKSPT----------HASLEGDGTLDLPRWVQ 449 V+ D + K D++S K P H + TL W Sbjct: 189 VILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSREWTD 248 Query: 450 SVVR 461 S R Sbjct: 249 SFRR 252
>TAOK3_MOUSE (Q8BYC6) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 39.7 bits (91), Expect = 0.004 Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 13/124 (10%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LH H+L H ++K+ N+LL + L+DF + +P+++ G + APE Sbjct: 131 ALQGLAYLHF-HSLIHRDIKAGNILL-TEPGQVKLADFGSASMASPANSFVGTPYWMAPE 188 Query: 309 VV---DTRRPTFKADVYSXXXXXXXXXTGKSPT----------HASLEGDGTLDLPRWVQ 449 V+ D + K D++S K P H + TL W Sbjct: 189 VILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSREWTD 248 Query: 450 SVVR 461 S R Sbjct: 249 SFRR 252
>TAOK3_CHICK (Q9I9E0) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Kinase from chicken) Length = 898 Score = 39.3 bits (90), Expect = 0.005 Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 3/78 (3%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPE 308 A +GLA+LHS H H ++K+ N+LL + L+DF I +P+++ G + APE Sbjct: 131 ALQGLAYLHS-HCKIHRDIKAGNILLT-EPGQVKLADFGSASIVSPANSFVGTPYWMAPE 188 Query: 309 VV---DTRRPTFKADVYS 353 V+ D + K DV+S Sbjct: 189 VILAMDEGQYDGKVDVWS 206
>STK24_MOUSE (Q99KH8) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| Length = 431 Score = 39.3 bits (90), Expect = 0.005 Identities = 39/141 (27%), Positives = 63/141 (44%), Gaps = 5/141 (3%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 KD KL ++ +YL GS +L P+D +GL +LHS + H Sbjct: 91 KDTKLWIIMEYLGGGSALDLLEPG------PLDEIQIATILREILKGLDYLHSEKKI-HR 143 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPS----STRAGAGGYRAPEVVDTRRPTFKADV 347 ++K++NVLL ++ L+DF + + +T G + APEV+ KAD+ Sbjct: 144 DIKAANVLLS-EHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADI 202 Query: 348 YSXXXXXXXXXTGKSPTHASL 410 +S G+ P H+ L Sbjct: 203 WSLGITAIELAKGE-PPHSEL 222
>ACVR1_RAT (P80201) Activin receptor type-1 precursor (EC 2.7.11.30) (Activin| receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) Length = 509 Score = 39.3 bits (90), Expect = 0.005 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 14/91 (15%) Frame = +3 Query: 87 TPMDWDARMRSALSASRGLAHLH-------STHNLAHGNVKSSNVLLR-------LDYDA 224 T +D + +R LS + GLAHLH +AH ++KS N+L++ D Sbjct: 298 TTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKSAIAHRDLKSKNILVKKNGQCCIADLGL 357 Query: 225 AALSDFCLHPIFAPSSTRAGAGGYRAPEVVD 317 A + + + ++ R G Y APEV+D Sbjct: 358 AVMHSQSTNQLDVGNNPRVGTKRYMAPEVLD 388
>ACVR1_MOUSE (P37172) Activin receptor type-1 precursor (EC 2.7.11.30) (Activin| receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) (TSK-7L) Length = 509 Score = 39.3 bits (90), Expect = 0.005 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 14/91 (15%) Frame = +3 Query: 87 TPMDWDARMRSALSASRGLAHLH-------STHNLAHGNVKSSNVLLR-------LDYDA 224 T +D + +R LS + GLAHLH +AH ++KS N+L++ D Sbjct: 298 TTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKSAIAHRDLKSKNILVKKNGQCCIADLGL 357 Query: 225 AALSDFCLHPIFAPSSTRAGAGGYRAPEVVD 317 A + + + ++ R G Y APEV+D Sbjct: 358 AVMHSQSTNQLDVGNNPRVGTKRYMAPEVLD 388
>DSOR1_DROME (Q24324) Dual specificity mitogen-activated protein kinase kinase| dSOR1 (EC 2.7.12.2) (Downstream of RAF) (MAPKK) Length = 396 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +Y+ GSL +L + +GR P R+ L+ +GL++L H + H +VK SN+L+ Sbjct: 163 EYMDGGSLDLIL---KRAGRIPESILGRI--TLAVLKGLSYLRDNHAIIHRDVKPSNILV 217 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 + + DF + I + +++ G Y +PE + + ++D++S Sbjct: 218 NSSGE-IKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMA 276 Query: 381 TGKSP 395 G P Sbjct: 277 IGMYP 281
>ST17A_RABIT (Q9GM70) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) (rDRAK1) Length = 397 Score = 38.9 bits (89), Expect = 0.007 Identities = 37/134 (27%), Positives = 53/134 (39%), Gaps = 5/134 (3%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVK 188 E +LV +Y G +S R D MR L G+ LH TH++ H ++K Sbjct: 116 EMILVLEYAAGGEISDQCVADRDEAFNEKDVQRLMRQILE---GVHFLH-THDVVHLDLK 171 Query: 189 SSNVLLRLDYDAAALS--DFCLHPIFAPSSTR---AGAGGYRAPEVVDTRRPTFKADVYS 353 N+LL + + DF L I S G Y APE++ + D++S Sbjct: 172 PQNILLTSESPLGDIKIVDFGLSRIVKNSEELREIMGTPEYVAPEILSYDPISMATDMWS 231 Query: 354 XXXXXXXXXTGKSP 395 TG SP Sbjct: 232 IGVLTYVMLTGISP 245
>STE20_YEAST (Q03497) Serine/threonine-protein kinase STE20 (EC 2.7.11.1)| Length = 939 Score = 38.9 bits (89), Expect = 0.007 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAML-HGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 K + ++ +Y+ GSL+ ++ H G+ A R LS GL LHS + H Sbjct: 687 KGDLWVIMEYMEGGSLTDVVTHCILTEGQI----GAVCRETLS---GLEFLHSK-GVLHR 738 Query: 180 NVKSSNVLLRLDYDAAALSD--FC--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADV 347 ++KS N+LL ++ D L+D FC ++ + +T G + APEVV + K D+ Sbjct: 739 DIKSDNILLSMEGD-IKLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDI 797 Query: 348 YSXXXXXXXXXTGKSP 395 +S G+ P Sbjct: 798 WSLGIMIIEMIEGEPP 813
>ACVR1_HUMAN (Q04771) Activin receptor type-1 precursor (EC 2.7.11.30) (Activin| receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (Activin receptor-like kinase 2) (ALK-2) (TGF-B superfamily receptor type I) (TSR-I) Length = 509 Score = 38.9 bits (89), Expect = 0.007 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 14/91 (15%) Frame = +3 Query: 87 TPMDWDARMRSALSASRGLAHLH-------STHNLAHGNVKSSNVLLR-------LDYDA 224 T +D + +R LS + GLAHLH +AH ++KS N+L++ D Sbjct: 298 TTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGL 357 Query: 225 AALSDFCLHPIFAPSSTRAGAGGYRAPEVVD 317 A + + + ++ R G Y APEV+D Sbjct: 358 AVMHSQSTNQLDVGNNPRVGTKRYMAPEVLD 388
>ACVR1_BOVIN (Q28041) Activin receptor type-1 precursor (EC 2.7.11.30) (Activin| receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) Length = 509 Score = 38.9 bits (89), Expect = 0.007 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 14/91 (15%) Frame = +3 Query: 87 TPMDWDARMRSALSASRGLAHLH-------STHNLAHGNVKSSNVLLR-------LDYDA 224 T +D + +R LS + GLAHLH +AH ++KS N+L++ D Sbjct: 298 TTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGL 357 Query: 225 AALSDFCLHPIFAPSSTRAGAGGYRAPEVVD 317 A + + + ++ R G Y APEV+D Sbjct: 358 AVMHSQSTNQLDVGNNPRVGTKRYMAPEVLD 388
>M4K4_MOUSE (P97820) Mitogen-activated protein kinase kinase kinase kinase 4| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase) Length = 1233 Score = 38.9 bits (89), Expect = 0.007 Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 4/107 (3%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 D+ LV ++ GS++ ++ ++G+ DW A + + RGLAHLH H++ H ++ Sbjct: 98 DQLWLVMEFCGAGSITDLVKNTKGN-TLKEDWIAYISREIL--RGLAHLH-IHHVIHRDI 153 Query: 186 KSSNVLLRLDYDAAALSDF----CLHPIFAPSSTRAGAGGYRAPEVV 314 K NVLL + + L DF L +T G + APEV+ Sbjct: 154 KGQNVLLTENAE-VKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVI 199
>M4K4_HUMAN (O95819) Mitogen-activated protein kinase kinase kinase kinase 4| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase) Length = 1239 Score = 38.9 bits (89), Expect = 0.007 Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 4/107 (3%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 D+ LV ++ GS++ ++ ++G+ DW A + + RGLAHLH H++ H ++ Sbjct: 99 DQLWLVMEFCGAGSITDLVKNTKGN-TLKEDWIAYISREIL--RGLAHLH-IHHVIHRDI 154 Query: 186 KSSNVLLRLDYDAAALSDF----CLHPIFAPSSTRAGAGGYRAPEVV 314 K NVLL + + L DF L +T G + APEV+ Sbjct: 155 KGQNVLLTENAE-VKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVI 200
>YQG4_CAEEL (Q09499) Putative serine/threonine-protein kinase C41C4.4 precursor| (EC 2.7.11.1) Length = 983 Score = 38.9 bits (89), Expect = 0.007 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 13/88 (14%) Frame = +3 Query: 129 ASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDA----AALSDFCLHPIFAP---------S 269 A+ GLAHLH++ + H ++K NVL+ + A +SDF L P + Sbjct: 636 ATDGLAHLHAS-KIVHRDMKPQNVLITMASQRGEMRAVISDFGLCKRVQPGKNSISRGIA 694 Query: 270 STRAGAGGYRAPEVVDTRRPTFKADVYS 353 S AG G+ APEV+ + ++ D++S Sbjct: 695 SGLAGTDGWIAPEVLISASTSYPVDIFS 722
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 38.9 bits (89), Expect = 0.007 Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 11/145 (7%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 LV +Y G L+ LH R + +R L G L + + H ++K N Sbjct: 90 LVMEYCNGGDLADYLHAMRTLS------EDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQN 143 Query: 198 VLLRLDYDAAA--------LSDFCLHPIFAPS---STRAGAGGYRAPEVVDTRRPTFKAD 344 +LL A ++DF + +T G+ Y APEV+ ++ KAD Sbjct: 144 ILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKAD 203 Query: 345 VYSXXXXXXXXXTGKSPTHASLEGD 419 ++S TGK+P AS D Sbjct: 204 LWSIGTIVYQCLTGKAPFQASSPQD 228
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 38.5 bits (88), Expect = 0.009 Identities = 45/162 (27%), Positives = 67/162 (41%), Gaps = 14/162 (8%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASR---GLAHLHSTHNLA 173 KD V ++L G L M H + GR + R+ A+ GL LH + Sbjct: 418 KDHLFFVMEFLNGGDL--MFH-IQDKGRFEL-----YRATFYAAEIICGLQFLHGK-GII 468 Query: 174 HGNVKSSNVLLRLDYDAAALSDF--CLHPIFAPS--STRAGAGGYRAPEVVDTRRPTFKA 341 + ++K NV+L D ++DF C IF + ST G Y APE++ + +F Sbjct: 469 YRDLKLDNVMLDKD-GHIKIADFGMCKENIFGENRASTFCGTPDYIAPEILQGLKYSFSV 527 Query: 342 DVYSXXXXXXXXXTGKSPTHASLEGD-------GTLDLPRWV 446 D +S G+SP H E + T PRW+ Sbjct: 528 DWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 569
>SKM1_YEAST (Q12469) Serine/threonine-protein kinase SKM1 (EC 2.7.11.1)| (Protein kinase 75490 D) Length = 655 Score = 38.5 bits (88), Expect = 0.009 Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 9/139 (6%) Frame = +3 Query: 6 DEKL-LVYDYLPNGSLS----AMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNL 170 DE+L ++ +Y+ G L+ A+ + G +P++ + +GL LH+ + Sbjct: 445 DEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNK-KI 503 Query: 171 AHGNVKSSNVLLRLDYDAAALSDF--CLHPIFAPS--STRAGAGGYRAPEVVDTRRPTFK 338 H ++KS N+LL ++DF C+ S +T G + APE+V+ + K Sbjct: 504 IHRDIKSDNILLN-SQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEK 562 Query: 339 ADVYSXXXXXXXXXTGKSP 395 DV+S G+ P Sbjct: 563 VDVWSLGIMLIEMIEGEPP 581
>MOS_CERAE (P10650) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 346 Score = 38.5 bits (88), Expect = 0.009 Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 7/109 (6%) Frame = +3 Query: 90 PMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDF-CLHPIF-- 260 P+ ++ +L GL LHS ++ H ++K +N+L+ + D +SDF C + Sbjct: 172 PLTLGKCLKYSLDVVNGLLFLHS-QSIVHLDLKPANILIS-EQDVCKISDFGCSEKLEDL 229 Query: 261 ----APSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 P G +RAPE++ T KAD+YS T ++P Sbjct: 230 LCFQTPLYPLGGTYTHRAPELLKGEGVTPKADIYSFAITLWQMTTKQAP 278
>STK25_HUMAN (O00506) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 38.1 bits (87), Expect = 0.011 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 4/91 (4%) Frame = +3 Query: 135 RGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPS----STRAGAGGYRA 302 +GL +LHS + H ++K++NVLL D L+DF + + +T G + A Sbjct: 126 KGLDYLHSERKI-HRDIKAANVLLSEQGDVK-LADFGVAGQLTDTQIKRNTFVGTPFWMA 183 Query: 303 PEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 PEV+ FKAD++S G+ P Sbjct: 184 PEVIKQSAYDFKADIWSLGITAIELAKGEPP 214
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 38.1 bits (87), Expect = 0.011 Identities = 42/144 (29%), Positives = 57/144 (39%), Gaps = 5/144 (3%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 LV + + G+L +L R PM A + GLA H L H +VK N Sbjct: 94 LVMELIEGGTLRELL-----IERGPMPPHAVVAVLRPVLGGLAAAHRA-GLVHRDVKPEN 147 Query: 198 VLLRLDYDAAALSDFCLHPIFAPSSTRA-----GAGGYRAPEVVDTRRPTFKADVYSXXX 362 +L+ D D L+DF L A +S + G Y +PE V ++DVYS Sbjct: 148 ILISDDGDVK-LADFGLVRAVAAASITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGV 206 Query: 363 XXXXXXTGKSPTHASLEGDGTLDL 434 TG H GD L + Sbjct: 207 LVYELLTG----HTPFTGDSALSI 226
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 38.1 bits (87), Expect = 0.011 Identities = 42/144 (29%), Positives = 57/144 (39%), Gaps = 5/144 (3%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 LV + + G+L +L R PM A + GLA H L H +VK N Sbjct: 94 LVMELIEGGTLRELL-----IERGPMPPHAVVAVLRPVLGGLAAAHRA-GLVHRDVKPEN 147 Query: 198 VLLRLDYDAAALSDFCLHPIFAPSSTRA-----GAGGYRAPEVVDTRRPTFKADVYSXXX 362 +L+ D D L+DF L A +S + G Y +PE V ++DVYS Sbjct: 148 ILISDDGDVK-LADFGLVRAVAAASITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGV 206 Query: 363 XXXXXXTGKSPTHASLEGDGTLDL 434 TG H GD L + Sbjct: 207 LVYELLTG----HTPFTGDSALSI 226
>MP2K2_CYPCA (Q90321) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 397 Score = 38.1 bits (87), Expect = 0.011 Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L +R R P + ++ +++ RGL +L H + H +VK SN+L+ Sbjct: 145 EHMDGGSLDQVLKEAR---RIPEEILGKV--SIAVLRGLVYLREKHQIMHRDVKPSNILV 199 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++DV+S Sbjct: 200 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDVWSMGLSLVELA 258 Query: 381 TGKSP 395 G+ P Sbjct: 259 IGRFP 263
>LIMK2_CHICK (P53666) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 642 Score = 38.1 bits (87), Expect = 0.011 Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 1/83 (1%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 KD+KL L+ +Y+ G+L L + P W ++ A + G+A+LHS + H Sbjct: 397 KDKKLNLLTEYIEGGTLKDFLRNA-----DPFPWQQKVSFAKGIASGMAYLHSM-CIIHR 450 Query: 180 NVKSSNVLLRLDYDAAALSDFCL 248 ++ S N L++LD ++DF L Sbjct: 451 DLNSHNCLIKLD-KTVVVADFGL 472
>MP2K2_CHICK (Q90891) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 398 Score = 38.1 bits (87), Expect = 0.011 Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L ++ R P + ++ +++ RGLA+L H + H +VK SN+L+ Sbjct: 146 EHMDGGSLDQVLKEAK---RIPEEILGKV--SIAVLRGLAYLREKHQIMHRDVKPSNILV 200 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++D++S Sbjct: 201 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELS 259 Query: 381 TGKSP 395 G+ P Sbjct: 260 IGRYP 264
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 38.1 bits (87), Expect = 0.011 Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 3/112 (2%) Frame = +3 Query: 138 GLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSST---RAGAGGYRAPE 308 GL LH + + ++K N+LL D+ +SD L T R G GY APE Sbjct: 298 GLEDLHR-ERIVYRDLKPENILLD-DHGHIRISDLGLTVHVPEGQTIKGRVGTVGYMAPE 355 Query: 309 VVDTRRPTFKADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 VV R TF D ++ G+SP + ++ R V+ V E Sbjct: 356 VVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEE 407
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 38.1 bits (87), Expect = 0.011 Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 4/135 (2%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAML-HGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 K + ++ +Y+ GSL+ ++ H G+ + R L +GL LHS + H Sbjct: 1021 KGDLWVIMEYMEGGSLTDIVTHSVMTEGQIGVV----CRETL---KGLKFLHSK-GVIHR 1072 Query: 180 NVKSSNVLLRLDYDAAALS-DFC--LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVY 350 ++KS N+LL +D + FC ++ I + T G + APE+V + K DV+ Sbjct: 1073 DIKSDNILLNMDGNIKITDFGFCAQINEINSKRITMVGTPYWMAPEIVSRKEYGPKVDVW 1132 Query: 351 SXXXXXXXXXTGKSP 395 S G+ P Sbjct: 1133 SLGIMIIEMLEGEPP 1147
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 38.1 bits (87), Expect = 0.011 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 5/91 (5%) Frame = +3 Query: 138 GLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRA-----GAGGYRA 302 GLA H + H ++K N+L+ D ++DF L + ++ + G Y A Sbjct: 127 GLASAHRA-GVVHRDIKPENILIN-DRGHVQITDFGLAKAASQATLSSTGMLLGTAAYLA 184 Query: 303 PEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 PE+++ + T + D+YS TGK P Sbjct: 185 PEMIENNQATAQGDLYSVGIMAWEMLTGKVP 215
>LIMK1_HUMAN (P53667) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 38.1 bits (87), Expect = 0.011 Identities = 34/136 (25%), Positives = 61/136 (44%), Gaps = 19/136 (13%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 KD++L + +Y+ G+L ++ S + W R+ A + G+A+LHS N+ H Sbjct: 405 KDKRLNFITEYIKGGTLRGIIK----SMDSQYPWSQRVSFAKDIASGMAYLHSM-NIIHR 459 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTR------------------AGAGGYRAP 305 ++ S N L+R + ++DF L + T+ G + AP Sbjct: 460 DLNSHNCLVR-ENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAP 518 Query: 306 EVVDTRRPTFKADVYS 353 E+++ R K DV+S Sbjct: 519 EMINGRSYDEKVDVFS 534
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 38.1 bits (87), Expect = 0.011 Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 11/137 (8%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTH--NLAHGNVKS 191 LV ++ G L+ +L G R ++W A+ +RG+ +LH + H ++KS Sbjct: 218 LVMEFARGGPLNRVLSGKRIPPDILVNW------AVQIARGMNYLHDEAIVPIIHRDLKS 271 Query: 192 SNVLLRLDYDAAALS-------DFCLHPIFAPSSTRAGAGGY--RAPEVVDTRRPTFKAD 344 SN+L+ + LS DF L + ++ + AG Y APEV+ + +D Sbjct: 272 SNILILQKVENGDLSNKILKITDFGLAREWHRTTKMSAAGTYAWMAPEVIRASMFSKGSD 331 Query: 345 VYSXXXXXXXXXTGKSP 395 V+S TG+ P Sbjct: 332 VWSYGVLLWELLTGEVP 348
>M3K8_RAT (Q63562) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (Tumor progression locus 2) (TPL-2) Length = 467 Score = 38.1 bits (87), Expect = 0.011 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Frame = +3 Query: 135 RGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCL-----HPIFAPSSTRAGAGGYR 299 +GL LHS + H ++K SN++ A L DF L ++ P R G Y Sbjct: 239 KGLDFLHSK-KVIHHDIKPSNIVFMST--KAVLVDFGLSVQMTEDVYLPKDLR-GTEIYM 294 Query: 300 APEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 +PEV+ R + KAD+YS TG P Sbjct: 295 SPEVILCRGHSTKADIYSLGATLIHMQTGTPP 326
>M3K8_MOUSE (Q07174) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 38.1 bits (87), Expect = 0.011 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Frame = +3 Query: 135 RGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCL-----HPIFAPSSTRAGAGGYR 299 +GL LHS + H ++K SN++ A L DF L ++ P R G Y Sbjct: 239 KGLDFLHSK-KVIHHDIKPSNIVFMST--KAVLVDFGLSVKMTEDVYLPKDLR-GTEIYM 294 Query: 300 APEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 +PEV+ R + KAD+YS TG P Sbjct: 295 SPEVILCRGHSTKADIYSLGATLIHMQTGTPP 326
>BUB1_SCHPO (O94751) Checkpoint serine/threonine-protein kinase bub1 (EC| 2.7.11.1) Length = 1044 Score = 38.1 bits (87), Expect = 0.011 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 2/89 (2%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGS--GRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 D L+ DY P GS+ +++ S + MD + ++ R + LH TH + HG Sbjct: 802 DTSHLLMDYRPQGSILDLVNSMHNSTFSSSGMDEILVVFFSIEFLRIIEALH-THKIIHG 860 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAP 266 ++K+ N LLRL+ ++D PI++P Sbjct: 861 DLKADNALLRLE----TVADSEWSPIYSP 885
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 38.1 bits (87), Expect = 0.011 Identities = 38/135 (28%), Positives = 55/135 (40%), Gaps = 9/135 (6%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRT---PMDWDARMRSALSASRGLAHLHST--HNLAHGN 182 L+ ++ GSL LHG + M W A + GLA+LH+ L H + Sbjct: 87 LIMEFAEGGSLHNFLHGKVKPAYSLAHAMSW------ARQCAEGLAYLHAMTPKPLIHRD 140 Query: 183 VKSSNVLLRLDYDAAALSDFCLHPIFAPSST----RAGAGGYRAPEVVDTRRPTFKADVY 350 VK N+LL + DF A ST G+ + APEV + + T K D++ Sbjct: 141 VKPLNLLLTNKGRNLKICDF---GTVADKSTMMTNNRGSAAWMAPEVFEGSKYTEKCDIF 197 Query: 351 SXXXXXXXXXTGKSP 395 S + K P Sbjct: 198 SWAIVLWEVLSRKQP 212
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 37.7 bits (86), Expect = 0.015 Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 11/145 (7%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 LV +Y G L+ LH R + +R L G L + + H ++K N Sbjct: 90 LVMEYCNGGDLADYLHTMRTLS------EDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQN 143 Query: 198 VLLRLDYDAAA--------LSDFCLHPIFAPS---STRAGAGGYRAPEVVDTRRPTFKAD 344 +LL A ++DF + +T G+ Y APEV+ ++ KAD Sbjct: 144 ILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKAD 203 Query: 345 VYSXXXXXXXXXTGKSPTHASLEGD 419 ++S TGK+P AS D Sbjct: 204 LWSIGTIVYQCLTGKAPFQASSPQD 228
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 3) Length = 651 Score = 37.7 bits (86), Expect = 0.015 Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 6/136 (4%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNV 185 D ++ +++P GS+S++L GS P+ + L GL +LH+ + + H ++ Sbjct: 144 DSLNILMEFVPGGSISSLLE-KFGSFPEPVIIMYTKQLLL----GLEYLHN-NGIMHRDI 197 Query: 186 KSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYR------APEVVDTRRPTFKADV 347 K +N+L+ + L+DF +T GA + APEV+ +F AD+ Sbjct: 198 KGANILVD-NKGCIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVILQTGHSFSADI 256 Query: 348 YSXXXXXXXXXTGKSP 395 +S TGK P Sbjct: 257 WSVGCTVIEMATGKPP 272
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 37.7 bits (86), Expect = 0.015 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 3/129 (2%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 LV D++ G L L+ +G R + AR+ +A S ++HLH + H ++K N Sbjct: 215 LVLDFINGGHLFFQLY-HQGLFREDL---ARVYTAEIVS-AVSHLHEK-GIMHRDLKPEN 268 Query: 198 VLLRLDYDAAALSDFCLHPIFAP---SSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXX 368 +L+ +D L+DF L F S++ G Y APE+V + AD +S Sbjct: 269 ILMDVD-GHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILL 327 Query: 369 XXXXTGKSP 395 TGK P Sbjct: 328 YEMLTGKPP 336
>TYK2_HUMAN (P29597) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1187 Score = 37.7 bits (86), Expect = 0.015 Identities = 24/66 (36%), Positives = 35/66 (53%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVK 188 E ++V +Y+ +G L L RG PM W +M A + L++L + NL HGNV Sbjct: 682 ENIMVTEYVEHGPLDVWLRRERG--HVPMAW--KMVVAQQLASALSYLENK-NLVHGNVC 736 Query: 189 SSNVLL 206 N+LL Sbjct: 737 GRNILL 742
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 37.7 bits (86), Expect = 0.015 Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 3/112 (2%) Frame = +3 Query: 138 GLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSST---RAGAGGYRAPE 308 GL LH + + ++K N+LL D+ +SD L T R G GY APE Sbjct: 298 GLEDLHR-ERIVYRDLKPENILLD-DHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPE 355 Query: 309 VVDTRRPTFKADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 VV R TF D ++ G+SP + ++ R V+ V E Sbjct: 356 VVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEE 407
>M3K8_HUMAN (P41279) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 37.7 bits (86), Expect = 0.015 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Frame = +3 Query: 135 RGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCL-----HPIFAPSSTRAGAGGYR 299 +GL LHS + H ++K SN++ A L DF L ++ P R G Y Sbjct: 239 KGLDFLHSK-KVIHHDIKPSNIVFMST--KAVLVDFGLSVQMTEDVYFPKDLR-GTEIYM 294 Query: 300 APEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 +PEV+ R + KAD+YS TG P Sbjct: 295 SPEVILCRGHSTKADIYSLGATLIHMQTGTPP 326
>MP2K1_CRIGR (Q63980) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 393 Score = 37.7 bits (86), Expect = 0.015 Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L + +GR P ++ +++ +GL +L H + H +VK SN+L+ Sbjct: 144 EHMDGGSLDQVL---KKAGRIPEQILGKV--SIAVIKGLTYLREKHKIMHRDVKPSNILV 198 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++D++S Sbjct: 199 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 257 Query: 381 TGKSP 395 G+ P Sbjct: 258 VGRYP 262
>MP2K1_RAT (Q01986) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 37.7 bits (86), Expect = 0.015 Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L + +GR P ++ +++ +GL +L H + H +VK SN+L+ Sbjct: 143 EHMDGGSLDQVL---KKAGRIPEQILGKV--SIAVIKGLTYLREKHKIMHRDVKPSNILV 197 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++D++S Sbjct: 198 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 256 Query: 381 TGKSP 395 G+ P Sbjct: 257 VGRYP 261
>MP2K1_RABIT (P29678) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 37.7 bits (86), Expect = 0.015 Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L + +GR P ++ +++ +GL +L H + H +VK SN+L+ Sbjct: 143 EHMDGGSLDQVL---KKAGRIPEQILGKV--SIAVIKGLTYLREKHKIMHRDVKPSNILV 197 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++D++S Sbjct: 198 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 256 Query: 381 TGKSP 395 G+ P Sbjct: 257 VGRYP 261
>MP2K1_MOUSE (P31938) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 37.7 bits (86), Expect = 0.015 Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L + +GR P ++ +++ +GL +L H + H +VK SN+L+ Sbjct: 143 EHMDGGSLDQVL---KKAGRIPEQILGKV--SIAVIKGLTYLREKHKIMHRDVKPSNILV 197 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++D++S Sbjct: 198 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 256 Query: 381 TGKSP 395 G+ P Sbjct: 257 VGRYP 261
>MP2K1_HUMAN (Q02750) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 37.7 bits (86), Expect = 0.015 Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L + +GR P ++ +++ +GL +L H + H +VK SN+L+ Sbjct: 143 EHMDGGSLDQVL---KKAGRIPEQILGKV--SIAVIKGLTYLREKHKIMHRDVKPSNILV 197 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++D++S Sbjct: 198 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 256 Query: 381 TGKSP 395 G+ P Sbjct: 257 VGRYP 261
>NRKB_TRYBB (Q03428) Putative serine/threonine-protein kinase B (EC 2.7.11.1)| Length = 431 Score = 37.7 bits (86), Expect = 0.015 Identities = 40/141 (28%), Positives = 60/141 (42%), Gaps = 7/141 (4%) Frame = +3 Query: 6 DEKLLVYDYLPNGSLSAMLHG-SRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGN 182 D L+V ++ +G+L + G R + +A + L L ++HS H + H + Sbjct: 90 DRLLIVMEFADSGNLDEQIKPWGTGDARYFQEHEA-LFLFLQLCLALDYIHS-HKMLHRD 147 Query: 183 VKSSNVLLRLDYDAAALSDFCLHPIFAPS------STRAGAGGYRAPEVVDTRRPTFKAD 344 +KS+NVLL L DF + + ST G Y APE+ + R KAD Sbjct: 148 IKSANVLLT-STGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNLRYNKKAD 206 Query: 345 VYSXXXXXXXXXTGKSPTHAS 407 V+S K P AS Sbjct: 207 VWSLGVLLYEIMGMKKPFSAS 227
>ANPRB_RAT (P16067) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 37.4 bits (85), Expect = 0.019 Identities = 48/164 (29%), Positives = 69/164 (42%), Gaps = 16/164 (9%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 +V +Y P GSL +L + +DW R +G+A LH++ +HG++KSSN Sbjct: 594 IVTEYCPRGSLQDILENDSIN----LDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSN 649 Query: 198 -------VLLRLDYDAAALSDFC----LHPIFAPSSTRAGAGGYRAPEVVD-TRRPTF-- 335 VL DY A+ H ++A + APE++ PT Sbjct: 650 CVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKL-------WTAPELLSGNPLPTTGM 702 Query: 336 -KADVYSXXXXXXXXXTGKSPTHASLEGDGTLDL-PRWVQSVVR 461 KADVYS P + LEG LDL P+ + VR Sbjct: 703 QKADVYSFAIILQEIALRSGPFY--LEG---LDLSPKEIVQKVR 741
>ANPRB_MOUSE (Q6VVW5) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 37.4 bits (85), Expect = 0.019 Identities = 48/164 (29%), Positives = 69/164 (42%), Gaps = 16/164 (9%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 +V +Y P GSL +L + +DW R +G+A LH++ +HG++KSSN Sbjct: 594 IVTEYCPRGSLQDILENDSIN----LDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSN 649 Query: 198 -------VLLRLDYDAAALSDFC----LHPIFAPSSTRAGAGGYRAPEVVD-TRRPTF-- 335 VL DY A+ H ++A + APE++ PT Sbjct: 650 CVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKL-------WTAPELLSGNPLPTTGM 702 Query: 336 -KADVYSXXXXXXXXXTGKSPTHASLEGDGTLDL-PRWVQSVVR 461 KADVYS P + LEG LDL P+ + VR Sbjct: 703 QKADVYSFAIILQEIALRSGPFY--LEG---LDLSPKEIVQKVR 741
>ANPRB_BOVIN (P46197) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 37.4 bits (85), Expect = 0.019 Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 15/127 (11%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 +V +Y P GSL +L + +DW R +G+A LH++ +HG++KSSN Sbjct: 594 IVTEYCPRGSLQDILENDSIN----LDWMFRYSLINDLVKGMAFLHNSIIASHGSLKSSN 649 Query: 198 -------VLLRLDYDAAALSDFC----LHPIFAPSSTRAGAGGYRAPEVVD-TRRPTF-- 335 VL DY A+ H ++A + APE++ PT Sbjct: 650 CVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKL-------WTAPELLSGNPLPTTGM 702 Query: 336 -KADVYS 353 KADVYS Sbjct: 703 QKADVYS 709
>SULU_CAEEL (P46549) Serine/threonine-protein kinase SULU (EC 2.7.11.1)| (Protein kinase 18) Length = 982 Score = 37.4 bits (85), Expect = 0.019 Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Frame = +3 Query: 141 LAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTRAGAGGYRAPEVV-- 314 L +LHS + H ++K+ N+LL D+ L+DF + P+ T G + APEV+ Sbjct: 141 LRYLHSLKRI-HRDIKAGNILLS-DHAIVKLADFGSASLVDPAQTFIGTPFFMAPEVILA 198 Query: 315 -DTRRPTFKADVYS 353 D T +AD++S Sbjct: 199 MDEGHYTDRADIWS 212
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 37.4 bits (85), Expect = 0.019 Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 5/135 (3%) Frame = +3 Query: 30 YLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLLR 209 Y+P SL + + R P+ + A GLA +H+ L H + K SN++L Sbjct: 94 YIPGPSLRKAV-----TERGPLYGNNLRTLAAGLVEGLAAIHAC-GLVHRDFKPSNIVLA 147 Query: 210 LDYDAAALSDFCL-HPIFAPSSTRAGAG----GYRAPEVVDTRRPTFKADVYSXXXXXXX 374 D + DF + P+ + T++GA Y +PE D + +DV+S Sbjct: 148 AD--GPRVIDFGVARPLDSSVMTQSGAVIGTLAYMSPEQTDGSQVGPASDVFSLGTVLAF 205 Query: 375 XXTGKSPTHASLEGD 419 TG+SP A G+ Sbjct: 206 AATGRSPFMADSIGE 220
>MP2K1_SERCA (Q91447) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment) Length = 388 Score = 37.4 bits (85), Expect = 0.019 Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L + +GR P ++ +++ +GL +L H + H +VK SN+L+ Sbjct: 137 EHMDGGSLDQVL---KKAGRIPEQILGKV--SIAVIKGLTYLREKHKIMHRDVKPSNILV 191 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++D++S Sbjct: 192 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 250 Query: 381 TGKSP 395 G+ P Sbjct: 251 IGRYP 255
>ACVL1_HUMAN (P37023) Serine/threonine-protein kinase receptor R3 precursor (EC| 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I) Length = 503 Score = 37.4 bits (85), Expect = 0.019 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 15/115 (13%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 L+ Y +GSL L R ++ +R A+SA+ GLAHLH +AH Sbjct: 275 LITHYHEHGSLYDFLQ------RQTLEPHLALRLAVSAACGLAHLHVEIFGTQGKPAIAH 328 Query: 177 GNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS--------TRAGAGGYRAPEVVD 317 + KS NVL++ + ++D L + + S R G Y APEV+D Sbjct: 329 RDFKSRNVLVKSNLQ-CCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLD 382
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 37.4 bits (85), Expect = 0.019 Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 3/112 (2%) Frame = +3 Query: 138 GLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSST---RAGAGGYRAPE 308 GL LH + + ++K N+LL D+ +SD L T R G GY APE Sbjct: 298 GLEDLHR-ERIVYRDLKPENILLD-DHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPE 355 Query: 309 VVDTRRPTFKADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 VV R TF D ++ G+SP + ++ R V+ V E Sbjct: 356 VVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEE 407
>STK25_MOUSE (Q9Z2W1) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 37.4 bits (85), Expect = 0.019 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 4/91 (4%) Frame = +3 Query: 135 RGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPS----STRAGAGGYRA 302 +GL +LHS + H ++K++NVLL D ++DF + + +T G + A Sbjct: 126 KGLDYLHSERKI-HRDIKAANVLLSEQGDVK-MADFGVAGQLTDTQIKRNTFVGTPFWMA 183 Query: 303 PEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 PEV+ FKAD++S G+ P Sbjct: 184 PEVIKQSAYDFKADIWSLGITAIELAKGEPP 214
>ANPRB_HUMAN (P20594) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 37.0 bits (84), Expect = 0.025 Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 15/127 (11%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 +V +Y P GSL +L + +DW R +G+A LH++ +HG++KSSN Sbjct: 594 IVTEYCPRGSLQDILENDSIN----LDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSN 649 Query: 198 -------VLLRLDYDAAALSDFC----LHPIFAPSSTRAGAGGYRAPEVVD-TRRPTF-- 335 VL DY A+ H ++A + APE++ PT Sbjct: 650 CVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKL-------WTAPELLSGNPLPTTGM 702 Query: 336 -KADVYS 353 KADVYS Sbjct: 703 QKADVYS 709
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 37.0 bits (84), Expect = 0.025 Identities = 39/129 (30%), Positives = 59/129 (45%), Gaps = 3/129 (2%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 LV D++ G L L+ +G R + AR+ +A S ++HLH + H ++K N Sbjct: 209 LVLDFINGGHLFFQLY-HQGLFREDL---ARVYTAEIVS-AVSHLHEK-GIMHRDLKPEN 262 Query: 198 VLLRLDYDAAALSDFCLHPIFAP---SSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXX 368 +L+ D L+DF L F S++ G Y APE+V + AD +S Sbjct: 263 ILMDTD-GHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILL 321 Query: 369 XXXXTGKSP 395 TGK P Sbjct: 322 YEMLTGKPP 330
>GCY3E_DROME (Q07553) Guanylate cyclase 32E precursor (EC 4.6.1.2)| Length = 1163 Score = 37.0 bits (84), Expect = 0.025 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 10/83 (12%) Frame = +3 Query: 135 RGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFA------PSSTRAGAGGY 296 +G+ +LH + ++HGN++SSN L+ + +SDF LH + A S Sbjct: 637 KGMIYLHDSEIISHGNLRSSNCLIDSRW-VCQISDFGLHELKAGQEEPNKSELELKRALC 695 Query: 297 RAPEVV-DTRRP---TFKADVYS 353 APE++ D RP + K DVYS Sbjct: 696 MAPELLRDAYRPGRGSQKGDVYS 718
>SHK2_SCHPO (Q10056) Serine/threonine-protein kinase shk2 (EC 2.7.11.1)| Length = 589 Score = 37.0 bits (84), Expect = 0.025 Identities = 33/117 (28%), Positives = 58/117 (49%), Gaps = 5/117 (4%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARM-RSALSASRGLAHLHSTHNLAHGNVKSS 194 +V +Y+ GSL+ ++ S+ + +A++ R L +G+ HLH+ N+ H ++KS Sbjct: 387 VVMEYMNAGSLTDIIEKSKLT-------EAQIARICLETCKGIQHLHA-RNIIHRDIKSD 438 Query: 195 NVLLRLDYDAAALSDFCLHPIFAPSS----TRAGAGGYRAPEVVDTRRPTFKADVYS 353 NVLL + ++DF + + T G + APEVV K D++S Sbjct: 439 NVLLD-NSGNIKITDFGFCARLSNRTNKRVTMVGTPYWMAPEVVKQNEYGTKVDIWS 494
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 37.0 bits (84), Expect = 0.025 Identities = 31/117 (26%), Positives = 58/117 (49%), Gaps = 8/117 (6%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +Y+ +G+L +L + + W R++ A + GL++LH + H ++ S N L+ Sbjct: 131 EYINSGNLEQLLDSN-----LYLPWTVRVKLAYDIAVGLSYLH-FKGIFHRDLTSKNCLI 184 Query: 207 RLDYD--AAALSDFCLHPIFAPSSTRA------GAGGYRAPEVVDTRRPTFKADVYS 353 + D + +A ++DF L +S + G+ + APEV+ KADV+S Sbjct: 185 KRDENGYSAVVADFGLAEKIPDASIGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFS 241
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 37.0 bits (84), Expect = 0.025 Identities = 32/117 (27%), Positives = 59/117 (50%), Gaps = 8/117 (6%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +Y+ +G+L +L + + W R++ A + GL++LH + H ++ S N L+ Sbjct: 131 EYINSGNLEQLLDSN-----LHLPWTVRVKLAYDIAVGLSYLH-FKGIFHRDLTSKNCLI 184 Query: 207 RLDYD--AAALSDFCLH---PIFAPSSTR---AGAGGYRAPEVVDTRRPTFKADVYS 353 + D + +A ++DF L P + S + G+ + APEV+ KADV+S Sbjct: 185 KRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFS 241
>KAND_SCHPO (Q10078) Putative serine/threonine-protein kinase C3H1.13 (EC| 2.7.11.1) Length = 344 Score = 37.0 bits (84), Expect = 0.025 Identities = 34/112 (30%), Positives = 50/112 (44%), Gaps = 19/112 (16%) Frame = +3 Query: 156 STHNLA---HGNVKSSNVLLRLDYDAAALSDF---CLHPIFAPSSTRAGA---------- 287 S +NL HG++K N+LL + L+DF CL PIFA +++ A A Sbjct: 183 SNNNLVSYIHGDIKPDNLLLHENSREIVLTDFGSICLVPIFASNNSEAIAIQDKASENCT 242 Query: 288 GGYRAPEVVDTRRP---TFKADVYSXXXXXXXXXTGKSPTHASLEGDGTLDL 434 +RAPE+ + T KAD++S SP + G+L L Sbjct: 243 MPFRAPELFHVKAGSTITEKADIWSFGCTLYTIMFHASPFEREVSQGGSLAL 294
>MST4_MOUSE (Q99JT2) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) Length = 416 Score = 36.6 bits (83), Expect = 0.033 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 K KL ++ +YL GS +L P D +GL +LHS + H Sbjct: 91 KGSKLWIIMEYLGGGSALDLLRAG------PFDEFQIATMLKEILKGLDYLHSEKKI-HR 143 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPS----STRAGAGGYRAPEVVDTRRPTFKADV 347 ++K++NVLL D L+DF + + +T G + APEV+ KAD+ Sbjct: 144 DIKAANVLLSEQGDVK-LADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADI 202 Query: 348 YSXXXXXXXXXTGKSP 395 +S G+ P Sbjct: 203 WSLGITAIELAKGEPP 218
>MST4_HUMAN (Q9P289) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase) Length = 416 Score = 36.6 bits (83), Expect = 0.033 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 K KL ++ +YL GS +L P D +GL +LHS + H Sbjct: 91 KGSKLWIIMEYLGGGSALDLLRAG------PFDEFQIATMLKEILKGLDYLHSEKKI-HR 143 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPS----STRAGAGGYRAPEVVDTRRPTFKADV 347 ++K++NVLL D L+DF + + +T G + APEV+ KAD+ Sbjct: 144 DIKAANVLLSEQGDVK-LADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADI 202 Query: 348 YSXXXXXXXXXTGKSP 395 +S G+ P Sbjct: 203 WSLGITAIELAKGEPP 218
>STK3_MOUSE (Q9JI10) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) Length = 497 Score = 36.6 bits (83), Expect = 0.033 Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 4/130 (3%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 +V +Y GS+S ++ R T + ++S L +GL +LH + H ++K+ N Sbjct: 97 IVMEYCGAGSVSDIIR-LRNKTLTEDEIATILKSTL---KGLEYLHFMRKI-HRDIKAGN 151 Query: 198 VLLRLDYDAAALSDFC----LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXX 365 +LL + A L+DF L A +T G + APEV+ AD++S Sbjct: 152 ILLNTE-GHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 210 Query: 366 XXXXXTGKSP 395 GK P Sbjct: 211 SIEMAEGKPP 220
>TYK2_MOUSE (Q9R117) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1180 Score = 36.6 bits (83), Expect = 0.033 Identities = 23/66 (34%), Positives = 35/66 (53%) Frame = +3 Query: 9 EKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVK 188 E ++V +++ +G L L RG + PM W +M A + L++L NL HGNV Sbjct: 675 ENIIVTEFVEHGPLDVWLRRQRG--QVPMTW--KMVVAQQLASALSYLEDK-NLVHGNVC 729 Query: 189 SSNVLL 206 N+LL Sbjct: 730 GRNILL 735
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 36.2 bits (82), Expect = 0.043 Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 4/130 (3%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 +V +Y GS+S ++ R T + ++S L +GL +LH + H ++K+ N Sbjct: 100 IVMEYCGAGSVSDIIR-LRNKTLTEDEIATILQSTL---KGLEYLHFMRKI-HRDIKAGN 154 Query: 198 VLLRLDYDAAALSDFC----LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXX 365 +LL + A L+DF L A +T G + APEV+ AD++S Sbjct: 155 ILLNTE-GHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 213 Query: 366 XXXXXTGKSP 395 GK P Sbjct: 214 AIEMAEGKPP 223
>MOS_XENLA (P12965) Serine/threonine-protein kinase mos (EC 2.7.11.1)| (pp39-mos) Length = 359 Score = 36.2 bits (82), Expect = 0.043 Identities = 35/125 (28%), Positives = 53/125 (42%), Gaps = 13/125 (10%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 ++ +Y G+L ++G P+ + MR A + GL LH + H ++K +N Sbjct: 140 IIMEYTGTGTLHQRIYGRS----PPLGAEICMRYARHVADGLRFLHRD-GVVHLDLKPAN 194 Query: 198 VLLRLDYDAAALSDFCLHPIFAPSSTRAGA----------GG---YRAPEVVDTRRPTFK 338 VLL D + DF AG GG +RAPE++ T K Sbjct: 195 VLLAPG-DLCKIGDFGCSQRLREGDEAAGGEPCCTQLRHVGGTYTHRAPELLKGEPVTAK 253 Query: 339 ADVYS 353 AD+YS Sbjct: 254 ADIYS 258
>MP2K3_MOUSE (O09110) Dual specificity mitogen-activated protein kinase kinase 3| (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3) Length = 347 Score = 36.2 bits (82), Expect = 0.043 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 7/85 (8%) Frame = +3 Query: 120 ALSASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTR---AGAG 290 A+S R L HLHS ++ H +VK SNVL+ + + DF + S + AG Sbjct: 170 AVSIVRALEHLHSKLSVIHRDVKPSNVLINKE-GHVKMCDFGISGYLVDSVAKTMDAGCK 228 Query: 291 GYRAPEVV----DTRRPTFKADVYS 353 Y APE + + + K+DV+S Sbjct: 229 PYMAPERINPELNQKGYNVKSDVWS 253
>MP2K3_HUMAN (P46734) Dual specificity mitogen-activated protein kinase kinase 3| (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3) Length = 347 Score = 36.2 bits (82), Expect = 0.043 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 7/85 (8%) Frame = +3 Query: 120 ALSASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPSSTR---AGAG 290 A+S R L HLHS ++ H +VK SNVL+ + + DF + S + AG Sbjct: 170 AVSIVRALEHLHSKLSVIHRDVKPSNVLINKE-GHVKMCDFGISGYLVDSVAKTMDAGCK 228 Query: 291 GYRAPEVV----DTRRPTFKADVYS 353 Y APE + + + K+DV+S Sbjct: 229 PYMAPERINPELNQKGYNVKSDVWS 253
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 36.2 bits (82), Expect = 0.043 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 5/135 (3%) Frame = +3 Query: 6 DEK--LLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 DEK L+ +YL NG L L GR+ + + L ++H N+ H Sbjct: 178 DEKRVYLLMEYLVNGELYKHL-----KGRSHFNDVVASYYVYQMADALDYMHE-RNILHR 231 Query: 180 NVKSSNVLLRLDYDAAALSDF---CLHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVY 350 ++K N+++ + + L+DF + P + T G Y +PE++ +R K DV+ Sbjct: 232 DIKPENIIIGFN-NTIKLTDFGWSVITPKGSKRKTLCGTVDYLSPELIRSREYNEKVDVW 290 Query: 351 SXXXXXXXXXTGKSP 395 + G P Sbjct: 291 ALGVLTYELLVGSPP 305
>TSSK6_MOUSE (Q925K9) Testis-specific serine/threonine-protein kinase 6 (EC| 2.7.11.1) (TSSK-6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK) Length = 273 Score = 36.2 bits (82), Expect = 0.043 Identities = 33/118 (27%), Positives = 48/118 (40%), Gaps = 5/118 (4%) Frame = +3 Query: 57 MLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALS 236 +L + +GR P ++ R S G H+L H ++K NVLL D ++ Sbjct: 97 LLQAVQRNGRIP---GSQARELFSQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKIT 153 Query: 237 DFCL----HPIFAPSSTRAGAGGYRAPEV-VDTRRPTFKADVYSXXXXXXXXXTGKSP 395 DF H S+T G+ Y +PEV + K DV+S TG P Sbjct: 154 DFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSLGVVLYVMVTGCMP 211
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 36.2 bits (82), Expect = 0.043 Identities = 31/117 (26%), Positives = 56/117 (47%), Gaps = 8/117 (6%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +Y+ +G+L +L + W R++ A + GL++LH + H ++ S N L+ Sbjct: 131 EYINSGNLEQLLDSD-----LYLPWTVRVKLAYDIAVGLSYLH-FKGIFHRDLTSKNCLI 184 Query: 207 RLDYD--AAALSDFCLHPIFAPSS------TRAGAGGYRAPEVVDTRRPTFKADVYS 353 + D + +A ++DF L +S G+ + APEV+ KADV+S Sbjct: 185 KRDENGYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRDEPYNEKADVFS 241
>LIMK1_RAT (P53669) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 36.2 bits (82), Expect = 0.043 Identities = 34/136 (25%), Positives = 61/136 (44%), Gaps = 19/136 (13%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 KD++L + +Y+ G+L ++ S + W R+ A + G+A+LHS N+ H Sbjct: 405 KDKRLNFITEYIKGGTLRGIIK----SMDSQYPWSQRVSFAKDIASGMAYLHSM-NIIHR 459 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPSS------------------TRAGAGGYRAP 305 ++ S N L+R + + ++DF L + T G + AP Sbjct: 460 DLNSHNCLVRENRN-VVVADFGLARLMIDEKGQSEDLRSLKKPDRKKRYTVVGNPYWMAP 518 Query: 306 EVVDTRRPTFKADVYS 353 E+++ R K DV+S Sbjct: 519 EMINGRSYDEKVDVFS 534
>GRK5_BOVIN (P43249) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 35.8 bits (81), Expect = 0.056 Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 4/135 (2%) Frame = +3 Query: 3 KDEKLLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGN 182 KD LV + G L ++ G + + + A GL LH N+ + + Sbjct: 256 KDALCLVLTIMNGGDLKFHIYNMGNPG---FEEERALFYAAEILCGLEDLHH-ENIVYRD 311 Query: 183 VKSSNVLLRLDYDAAALSDFCLHPIFAPSST----RAGAGGYRAPEVVDTRRPTFKADVY 350 +K N+LL DY +SD L + P R G GY APEV++ +R D + Sbjct: 312 LKPENILLD-DYGHIRISDLGL-AVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYW 369 Query: 351 SXXXXXXXXXTGKSP 395 G+SP Sbjct: 370 GLGCLIYEMIEGQSP 384
>ANPRA_HUMAN (P16066) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1061 Score = 35.8 bits (81), Expect = 0.056 Identities = 34/126 (26%), Positives = 51/126 (40%), Gaps = 14/126 (11%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 ++ +Y P GSL +L +DW R +G+ LH+ +HGN+KSSN Sbjct: 610 ILTEYCPRGSLQDILENES----ITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSN 665 Query: 198 -------VLLRLDYDAAALSDFCL---HPIFAPSSTRAGAGGYRAPEVVDTRRPTFK--- 338 VL DY + D H ++A + APE++ P + Sbjct: 666 CVVDGRFVLKITDYGLESFRDLDPEQGHTVYAKKL-------WTAPELLRMASPPVRGSQ 718 Query: 339 -ADVYS 353 DVYS Sbjct: 719 AGDVYS 724
>MP2K5_RAT (Q62862) Dual specificity mitogen-activated protein kinase kinase 5| (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5) Length = 448 Score = 35.8 bits (81), Expect = 0.056 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 2/119 (1%) Frame = +3 Query: 114 RSALSASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPS--STRAGA 287 R A++ +GL +L S + H +VK SN+L+ L DF + S T G Sbjct: 262 RIAVAVVKGLTYLWSL-KILHRDVKPSNMLVNTS-GQVKLCDFGVSTQLVNSIAKTYVGT 319 Query: 288 GGYRAPEVVDTRRPTFKADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 Y APE + + +DV+S G+ P + G+L + +Q +V E Sbjct: 320 NAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDE 378
>MOS_MSVMH (P07331) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 35.8 bits (81), Expect = 0.056 Identities = 34/138 (24%), Positives = 65/138 (47%), Gaps = 12/138 (8%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSG-----RTPMDWDARMRSALSASRGLAHLHSTHNLAHGN 182 ++ ++ N +L +++G+ S R + ++ +L GL LHS ++ H + Sbjct: 171 IIMEFGGNVTLHQVIYGATRSPEPLSCREQLSLGKCLKYSLDVVNGLLFLHS-QSILHLD 229 Query: 183 VKSSNVLLRLDYDAAALSDF-C---LHPIFAPSSTRAGAGG---YRAPEVVDTRRPTFKA 341 +K +N+L+ + D +SDF C L + ++ GG ++APE++ T KA Sbjct: 230 LKPANILIS-EQDVCKISDFGCSQKLQDLRCRQASPHHIGGTYTHQAPEILKGEIATPKA 288 Query: 342 DVYSXXXXXXXXXTGKSP 395 D+YS T + P Sbjct: 289 DIYSFGITLWQMTTREVP 306
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 35.8 bits (81), Expect = 0.056 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 5/77 (6%) Frame = +3 Query: 138 GLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALS--DFCLHPIFAPSS---TRAGAGGYRA 302 G+ +LH HN+ H ++K N+LL + + DF L F+ + R G Y A Sbjct: 177 GICYLHK-HNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKLRDRLGTAYYIA 235 Query: 303 PEVVDTRRPTFKADVYS 353 PEV+ ++ K DV+S Sbjct: 236 PEVL-RKKYNEKCDVWS 251
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 35.8 bits (81), Expect = 0.056 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 5/77 (6%) Frame = +3 Query: 138 GLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALS--DFCLHPIFAPSS---TRAGAGGYRA 302 G+ +LH HN+ H ++K N+LL + + DF L F+ + R G Y A Sbjct: 177 GICYLHK-HNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKLRDRLGTAYYIA 235 Query: 303 PEVVDTRRPTFKADVYS 353 PEV+ ++ K DV+S Sbjct: 236 PEVL-RKKYNEKCDVWS 251
>PKND_MYCTU (O05871) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 664 Score = 35.8 bits (81), Expect = 0.056 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 5/99 (5%) Frame = +3 Query: 123 LSASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCL-----HPIFAPSSTRAGA 287 ++A+ AH + + H +VK N+L+ D A L DF + P + T G Sbjct: 122 IAAALDAAH---ANGVTHRDVKPENILVTAS-DFAYLVDFGIARAASDPGLTQTGTAVGT 177 Query: 288 GGYRAPEVVDTRRPTFKADVYSXXXXXXXXXTGKSPTHA 404 Y APE T++AD+Y+ TG P A Sbjct: 178 YNYMAPERFTGDEVTYRADIYALACVLGECLTGAPPYRA 216
>PKAB_STRCO (P54740) Serine/threonine protein kinase pkaB (EC 2.7.11.1)| Length = 417 Score = 35.8 bits (81), Expect = 0.056 Identities = 31/110 (28%), Positives = 46/110 (41%), Gaps = 12/110 (10%) Frame = +3 Query: 102 DARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLLRLD-------YDAAALSDFCLHPIF 260 +A + + GLA H+ + H +VK NVLL + A L+DF + + Sbjct: 105 EAAVAVVADVADGLAAAHAA-GVVHRDVKPENVLLDMQGPLGPGGSHPALLTDFGVAKLI 163 Query: 261 -APSSTRA----GAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 P TRA G Y APE+V+ P D+Y+ G +P Sbjct: 164 DTPRRTRATKIIGTPDYLAPEIVEGLPPRAAVDIYALATVLYELLAGFTP 213
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 35.8 bits (81), Expect = 0.056 Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 19/136 (13%) Frame = +3 Query: 3 KDEKL-LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHG 179 K+++L + +Y+ G+L ++ S + W R+ A + G+A+LHS N+ H Sbjct: 412 KEKRLNFITEYIKGGTLRGLIK----SMDSHYPWSQRVSFAKDIAAGMAYLHSM-NIIHR 466 Query: 180 NVKSSNVLLRLDYDAAALSDFCLHPIFAPSS------------------TRAGAGGYRAP 305 ++ S N L+R + + ++DF L + T G + AP Sbjct: 467 DLNSHNCLVR-ENKSVVVADFGLARLMVDEKNQPEHLQNLKKPDRKKRYTVVGNPYWMAP 525 Query: 306 EVVDTRRPTFKADVYS 353 E+++ R K D++S Sbjct: 526 EMINGRSYDEKVDIFS 541
>MP2K1_XENLA (Q05116) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 394 Score = 35.8 bits (81), Expect = 0.056 Identities = 28/125 (22%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +3 Query: 27 DYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSNVLL 206 +++ GSL +L + +G+ P ++ +++ +GL +L H + H +VK SN+L+ Sbjct: 143 EHMDGGSLDQVL---KKAGKIPEKILGKV--SIAVIKGLTYLREKHKIMHRDVKPSNILV 197 Query: 207 RLDYDAAALSDFCL--HPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXXXXXXX 380 L DF + I + +++ G Y +PE + + ++D++S Sbjct: 198 N-SRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA 256 Query: 381 TGKSP 395 G+ P Sbjct: 257 IGRYP 261
>ACVL1_PONPY (Q5RAN0) Serine/threonine-protein kinase receptor R3 precursor (EC| 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) Length = 503 Score = 35.8 bits (81), Expect = 0.056 Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 15/115 (13%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLH-------STHNLAH 176 L+ Y +GSL L R ++ +R +SA+ GLAHLH +AH Sbjct: 275 LITHYHEHGSLYDFLQ------RQTLEPHLALRLTVSAACGLAHLHVEIFGTQGKPAIAH 328 Query: 177 GNVKSSNVLLRLDYDAAALSDFCLHPIFAPSS--------TRAGAGGYRAPEVVD 317 + KS NVL++ + ++D L + + S R G Y APEV+D Sbjct: 329 RDFKSRNVLVKSNLQ-CCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLD 382
>STK3_HUMAN (Q13188) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1) Length = 491 Score = 35.8 bits (81), Expect = 0.056 Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 4/130 (3%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSSN 197 +V +Y GS+S ++ R +T ++ D S +GL +LH + H ++K+ N Sbjct: 97 IVMEYCGAGSVSDII---RLRNKTLIE-DEIATILKSTLKGLEYLHFMRKI-HRDIKAGN 151 Query: 198 VLLRLDYDAAALSDFC----LHPIFAPSSTRAGAGGYRAPEVVDTRRPTFKADVYSXXXX 365 +LL + A L+DF L A +T G + APEV+ AD++S Sbjct: 152 ILLNTE-GHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 210 Query: 366 XXXXXTGKSP 395 GK P Sbjct: 211 SIEMAEGKPP 220
>NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a) Length = 692 Score = 35.8 bits (81), Expect = 0.056 Identities = 26/116 (22%), Positives = 54/116 (46%), Gaps = 3/116 (2%) Frame = +3 Query: 15 LLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSS 194 ++ +Y P G+L+ + S ++ + + + L H+H TH + H ++K+ Sbjct: 77 MIAMEYAPGGTLAEFIQKRCNS---LLEEETILHFFVQILLALHHVH-THLILHRDLKTQ 132 Query: 195 NVLLRLDYDAAALSDFCLHPIFAPSS---TRAGAGGYRAPEVVDTRRPTFKADVYS 353 N+LL + DF + I + S T G Y +PE+ + + K+D+++ Sbjct: 133 NILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWA 188
>MOS_MSVTS (P10421) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 342 Score = 35.8 bits (81), Expect = 0.056 Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 11/137 (8%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSG-----RTPMDWDARMRSALSASRGLAHLHSTHNLAHGN 182 ++ ++ N +L +++G+ S R + ++ +L GL LHS ++ H + Sbjct: 140 IIMEFGGNVTLHQVIYGATRSPEPLSCREQLSLGKCLKYSLDVVNGLLFLHS-QSILHLD 198 Query: 183 VKSSNVLLRLDYDAAALSDF-C---LHPIFAPSSTRAGAGGY--RAPEVVDTRRPTFKAD 344 +K +N+L+ + D +SDF C L + S G Y +APE++ T KAD Sbjct: 199 LKPANILIS-EQDVCKISDFGCSQKLQDLRCRQSPHHIGGTYTHQAPEILKGEIATPKAD 257 Query: 345 VYSXXXXXXXXXTGKSP 395 +YS T + P Sbjct: 258 IYSFGITLWQMTTREVP 274
>MOS_MOUSE (P00536) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 390 Score = 35.8 bits (81), Expect = 0.056 Identities = 33/138 (23%), Positives = 63/138 (45%), Gaps = 12/138 (8%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSG-----RTPMDWDARMRSALSASRGLAHLHSTHNLAHGN 182 ++ ++ N +L +++G+ S R + ++ +L GL LHS ++ H + Sbjct: 187 IIMEFGGNVTLHQVIYGATRSPEPLSCREQLSLGKCLKYSLDVVNGLLFLHS-QSILHLD 245 Query: 183 VKSSNVLLRLDYDAAALSDF-CLHPIFAPSSTRA------GAGGYRAPEVVDTRRPTFKA 341 +K +N+L+ + D +SDF C + +A G ++APE++ T KA Sbjct: 246 LKPANILIS-EQDVCKISDFGCSQKLQVLRCRQASPHHIGGTYTHQAPEILKGEIATPKA 304 Query: 342 DVYSXXXXXXXXXTGKSP 395 D+YS T + P Sbjct: 305 DIYSFGITLWQMTTREVP 322
>NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) Length = 698 Score = 35.8 bits (81), Expect = 0.056 Identities = 26/116 (22%), Positives = 54/116 (46%), Gaps = 3/116 (2%) Frame = +3 Query: 15 LLVYDYLPNGSLSAMLHGSRGSGRTPMDWDARMRSALSASRGLAHLHSTHNLAHGNVKSS 194 ++ +Y P G+L+ + S ++ + + + L H+H TH + H ++K+ Sbjct: 77 MIAMEYAPGGTLAEFIQKRCNS---LLEEETILHFFVQILLALHHVH-THLILHRDLKTQ 132 Query: 195 NVLLRLDYDAAALSDFCLHPIFAPSS---TRAGAGGYRAPEVVDTRRPTFKADVYS 353 N+LL + DF + I + S T G Y +PE+ + + K+D+++ Sbjct: 133 NILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWA 188
>MOS_MSVMM (P00537) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 376 Score = 35.8 bits (81), Expect = 0.056 Identities = 34/138 (24%), Positives = 65/138 (47%), Gaps = 12/138 (8%) Frame = +3 Query: 18 LVYDYLPNGSLSAMLHGSRGSG-----RTPMDWDARMRSALSASRGLAHLHSTHNLAHGN 182 ++ ++ N +L +++G+ S R + ++ +L GL LHS ++ H + Sbjct: 171 IIMEFGGNVTLHQVIYGATRSPEPLSCREQLSLGKCLKYSLDVVNGLLFLHS-QSILHLD 229 Query: 183 VKSSNVLLRLDYDAAALSDF-C---LHPIFAPSSTRAGAGG---YRAPEVVDTRRPTFKA 341 +K +N+L+ + D +SDF C L + ++ GG ++APE++ T KA Sbjct: 230 LKPANILIS-EQDVCKISDFGCSQKLQDLRCRQASPHHIGGTYTHQAPEILKGEIATPKA 288 Query: 342 DVYSXXXXXXXXXTGKSP 395 D+YS T + P Sbjct: 289 DIYSFGITLWQMTTREVP 306
>MOS_MSVMO (P00538) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 35.4 bits (80), Expect = 0.073 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 7/102 (6%) Frame = +3 Query: 111 MRSALSASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDF-C---LHPIFAPSSTR 278 ++ +L GL LHS ++ H ++K +N+L+ + D +SDF C L + ++ Sbjct: 207 LKYSLDVVNGLLFLHS-QSILHLDLKPANILIS-EQDVCKISDFGCSQKLQDLRGRQASP 264 Query: 279 AGAGG---YRAPEVVDTRRPTFKADVYSXXXXXXXXXTGKSP 395 GG ++APE++ T KAD+YS T + P Sbjct: 265 PHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVP 306
>MP2K5_MOUSE (Q9WVS7) Dual specificity mitogen-activated protein kinase kinase 5| (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5) Length = 448 Score = 35.4 bits (80), Expect = 0.073 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 2/119 (1%) Frame = +3 Query: 114 RSALSASRGLAHLHSTHNLAHGNVKSSNVLLRLDYDAAALSDFCLHPIFAPS--STRAGA 287 R A++ +GL +L S + H +VK SN+L+ L DF + S T G Sbjct: 262 RIAVAVVKGLTYLWSL-KILHRDVKPSNMLVNTG-GQVKLCDFGVSTQLVNSIAKTYVGT 319 Query: 288 GGYRAPEVVDTRRPTFKADVYSXXXXXXXXXTGKSPTHASLEGDGTLDLPRWVQSVVRE 464 Y APE + + +DV+S G+ P + G+L + +Q +V E Sbjct: 320 NAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDE 378 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 54,041,640 Number of Sequences: 219361 Number of extensions: 926146 Number of successful extensions: 4748 Number of sequences better than 10.0: 395 Number of HSP's better than 10.0 without gapping: 4405 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4618 length of database: 80,573,946 effective HSP length: 102 effective length of database: 58,199,124 effective search space used: 3026354448 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
