>DCR1B_CHICK (Q5QJC3) DNA cross-link repair 1B protein (chSNM1B)|
          Length = 457

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 43/104 (41%), Positives = 57/104 (54%)
 Frame = +2

Query: 161 SGGSQVYFLTHLHLDHTRGLGASGGWRHGPLYCSPATARLLPIRFPGVDASLLRPVXXXX 340
           +GG++++FL+H+H DHT GL ++  W   PLYCSP TARLL  R   V    +RP+    
Sbjct: 21  AGGARLFFLSHMHSDHTVGLSST--WSR-PLYCSPLTARLLHHRLK-VPTRWIRPLEVGQ 76

Query: 341 XXXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFRSDIGCMLY 472
                           + VT L A HCPGS+MFLF    G +LY
Sbjct: 77  SHAVGE---------EVTVTLLDANHCPGSVMFLFEGAFGTILY 111

>DCR1B_MOUSE (Q8C7W7) DNA cross-link repair 1B protein|
          Length = 541

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 40/104 (38%), Positives = 55/104 (52%)
 Frame = +2

Query: 161 SGGSQVYFLTHLHLDHTRGLGASGGWRHGPLYCSPATARLLPIRFPGVDASLLRPVXXXX 340
           +G ++++FLTH+H DHT GL ++  W   PLYCSP TA LL  R   V    +R +    
Sbjct: 21  AGSARLFFLTHMHCDHTVGLSST--WAR-PLYCSPITACLLHRRLQ-VSKHWIRALEVGE 76

Query: 341 XXXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFRSDIGCMLY 472
                          ++ VT + A HCPGS+MFLF    G +LY
Sbjct: 77  SHVLPLDEIGQE---TMTVTLIDANHCPGSVMFLFEGYFGTILY 117

>DCR1B_HUMAN (Q9H816) DNA cross-link repair 1B protein (hSNM1B)|
          Length = 532

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 40/104 (38%), Positives = 54/104 (51%)
 Frame = +2

Query: 161 SGGSQVYFLTHLHLDHTRGLGASGGWRHGPLYCSPATARLLPIRFPGVDASLLRPVXXXX 340
           +G ++++FL+H+H DHT GL  S  W   PLYCSP TA LL  R   V    ++ +    
Sbjct: 21  AGTARLFFLSHMHSDHTVGL--SSTWAR-PLYCSPITAHLLH-RHLQVSKQWIQALEVGE 76

Query: 341 XXXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFRSDIGCMLY 472
                          ++ VT L A HCPGS+MFLF    G +LY
Sbjct: 77  SHVLPLDEIGQ---ETMTVTLLDANHCPGSVMFLFEGYFGTILY 117

>DCR1C_RAT (Q5XIX3) Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C|
           protein) (SNM1-like protein)
          Length = 698

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 42/121 (34%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
 Frame = +2

Query: 143 VSVDKFSGGS---QVYFLTHLHLDHTRGLGASGGWRHGP------LYCSPATARLLPIRF 295
           +S+D+F   +   + YFL+H H DH +GL A    R         LYCSP T  LL +  
Sbjct: 14  ISIDRFDRENLKARAYFLSHCHKDHMKGLRAPSMKRRLECSLKVFLYCSPVTKELL-LTS 72

Query: 296 PGVD--ASLLRPVXXXXXXXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFRSDIGCML 469
           P      + +  +              SG    + VT LPA HCPGS+MFLF+   G +L
Sbjct: 73  PKYKFWENRIIAIEIETPTQVSLVDEASGEKEEVVVTLLPAGHCPGSVMFLFQGSNGTVL 132

Query: 470 Y 472
           Y
Sbjct: 133 Y 133

>SNM1_ARATH (Q38961) DNA cross-link repair protein SNM1 (AtSNM1)|
          Length = 484

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 35/94 (37%), Positives = 45/94 (47%)
 Frame = +2

Query: 167 GSQVYFLTHLHLDHTRGLGASGGWRHGPLYCSPATARLLPIRFPGVDASLLRPVXXXXXX 346
           G   YFLTH H DH  GL  +  W HGP+YCS  T+RLL +    V+ S + P+      
Sbjct: 168 GCSAYFLTHFHADHYIGL--TKAWSHGPIYCSSLTSRLLRLSL-SVNPSSIHPLELDVEY 224

Query: 347 XXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFR 448
                         I VT + A HCPG+ +  FR
Sbjct: 225 TIN----------GIKVTLIEANHCPGAALIHFR 248

>DCR1C_CHICK (Q5QJC2) Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C|
           protein) (chSNM1C) (SNM1-like protein)
          Length = 714

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 41/120 (34%), Positives = 56/120 (46%), Gaps = 10/120 (8%)
 Frame = +2

Query: 143 VSVDKFSGGS---QVYFLTHLHLDHTRGLGASGGWRH------GPLYCSPATARLLPIRF 295
           +S+D+F   +   + YFL+H H DH +GL A    R         LYCSP T  LL    
Sbjct: 14  LSIDRFDYDNLRARAYFLSHCHKDHMKGLRAPALRRRLQSSLKVKLYCSPVTKELLLTNS 73

Query: 296 P-GVDASLLRPVXXXXXXXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFRSDIGCMLY 472
                 + +  +              +G    I VT LPA HCPGS+MFLF+ + G +LY
Sbjct: 74  KYAFWENHIVALEVETPTQISLVDETTGEKEDIEVTLLPAGHCPGSVMFLFQGENGTVLY 133

>DCR1C_MOUSE (Q8K4J0) Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C|
           protein) (mArt protein) (SNM1-like protein)
          Length = 705

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 42/121 (34%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
 Frame = +2

Query: 143 VSVDKFSGGS---QVYFLTHLHLDHTRGLGASGGWRHGP------LYCSPATARLLPIRF 295
           +S+D+F   +   + YFL+H H DH +GL A    R         LYCSP T  LL +  
Sbjct: 14  ISIDRFDRENLKARAYFLSHCHKDHMKGLRAPSLKRRLECSLKVFLYCSPVTKELL-LTS 72

Query: 296 PGVD--ASLLRPVXXXXXXXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFRSDIGCML 469
           P      + +  +              SG    + VT LPA HCPGS+MFLF+   G +L
Sbjct: 73  PKYRFWENRIITIEIETPTQISLVDEASGEKEEVVVTLLPAGHCPGSVMFLFQGSNGTVL 132

Query: 470 Y 472
           Y
Sbjct: 133 Y 133

>DCR1C_PONPY (Q5R6Z9) Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C|
           protein)
          Length = 692

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 44/121 (36%), Positives = 58/121 (47%), Gaps = 11/121 (9%)
 Frame = +2

Query: 143 VSVDKFSGGS---QVYFLTHLHLDHTRGLGASGGWRHGP------LYCSPATARLLPIRF 295
           +S+D+F   +   + YFL+H H DH +GL A    R         LYCSP T  LL +  
Sbjct: 14  ISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELL-LTS 72

Query: 296 PGVDASLLRPVXXXXXXXXXXXXPN--SGRPVSIHVTALPALHCPGSLMFLFRSDIGCML 469
           P       R +             +  SG    I VT LPA HCPGS+MFLF+ + G +L
Sbjct: 73  PKYRFWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTVL 132

Query: 470 Y 472
           Y
Sbjct: 133 Y 133

>DCR1C_HUMAN (Q96SD1) Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C|
           protein) (SNM1-like protein) (A-SCID protein) (hSNM1C)
          Length = 692

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 44/121 (36%), Positives = 58/121 (47%), Gaps = 11/121 (9%)
 Frame = +2

Query: 143 VSVDKFSGGS---QVYFLTHLHLDHTRGLGASGGWRHGP------LYCSPATARLLPIRF 295
           +S+D+F   +   + YFL+H H DH +GL A    R         LYCSP T  LL +  
Sbjct: 14  ISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELL-LTS 72

Query: 296 PGVDASLLRPVXXXXXXXXXXXXPN--SGRPVSIHVTALPALHCPGSLMFLFRSDIGCML 469
           P       R +             +  SG    I VT LPA HCPGS+MFLF+ + G +L
Sbjct: 73  PKYRFWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTVL 132

Query: 470 Y 472
           Y
Sbjct: 133 Y 133

>PSO2_SCHPO (Q10264) DNA cross-link repair protein pso2/snm1 (EC 3.1.-.-)|
          Length = 560

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 38/106 (35%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
 Frame = +2

Query: 146 SVDKFSGGS----QVYFLTHLHLDHTRGLGASGGWRHGPLYCSPATARLLPIRFPGVDAS 313
           +VD F+ G+    + YFL+H H DH  GL     W+HGP+YCS  T  LL I    VD  
Sbjct: 196 AVDAFAYGAIDGVEAYFLSHFHSDHYGGLTPK--WKHGPIYCSEVTGNLL-INVMHVDEQ 252

Query: 314 LLRPVXXXXXXXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFRS 451
            ++ +            P +   ++++V  L A HCPGS MF+F +
Sbjct: 253 YVKRL--------KLNQPYNIMGITVYV--LDANHCPGSAMFVFET 288

>DCR1C_BRARE (Q5RGE5) Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C|
           protein)
          Length = 639

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/128 (31%), Positives = 57/128 (44%), Gaps = 18/128 (14%)
 Frame = +2

Query: 143 VSVDKFSGGS---QVYFLTHLHLDHTRGLGASGGWRHGPL-------------YCSPATA 274
           +S+D+F   +   + YFL+H H DH +GL        GPL             YCS  T 
Sbjct: 14  ISLDRFDRENLHARAYFLSHCHKDHMKGL-------KGPLLKRKLKFSLTVKLYCSYVTK 66

Query: 275 RLLPI--RFPGVDASLLRPVXXXXXXXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFR 448
            LL    R+   +  ++ P+             ++G    + VT L A HCPGS+MFLF 
Sbjct: 67  ELLLSNPRYAFWEDHIV-PLELDSPTSISLIDESTGETEDVVVTLLSAGHCPGSVMFLFE 125

Query: 449 SDIGCMLY 472
              G +LY
Sbjct: 126 GAKGTVLY 133

>DCR1A_MOUSE (Q9JIC3) DNA cross-link repair 1A protein|
          Length = 1026

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 32/101 (31%), Positives = 41/101 (40%)
 Frame = +2

Query: 167 GSQVYFLTHLHLDHTRGLGASGGWRHGPLYCSPATARLLPIRFPGVDASLLRPVXXXXXX 346
           G   YFLTH H DH  GL         P+YCS  T  LL  +   V    +R +      
Sbjct: 710 GCTAYFLTHFHSDHYAGLSKDFT---RPVYCSEITGNLLKKKLR-VQEQYIRQLPMDTEC 765

Query: 347 XXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFRSDIGCML 469
                        S+ V  L A HCPG+ M LF+   G ++
Sbjct: 766 VVD----------SVKVVLLDANHCPGATMILFQLPNGAVI 796

>DCR1A_HUMAN (Q6PJP8) DNA cross-link repair 1A protein (hSNM1) (hSNM1A)|
          Length = 1040

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 30/93 (32%), Positives = 38/93 (40%)
 Frame = +2

Query: 167 GSQVYFLTHLHLDHTRGLGASGGWRHGPLYCSPATARLLPIRFPGVDASLLRPVXXXXXX 346
           G   YFLTH H DH  GL     +   P+YCS  T  LL  +   V    + P+      
Sbjct: 724 GCTAYFLTHFHSDHYAGLSKHFTF---PVYCSEITGNLLKNKL-HVQEQYIHPLPLDTEC 779

Query: 347 XXXXXXPNSGRPVSIHVTALPALHCPGSLMFLF 445
                         + V  L A HCPG++M LF
Sbjct: 780 IVN----------GVKVVLLDANHCPGAVMILF 802

>PSO2_YEAST (P30620) DNA cross-link repair protein PSO2/SNM1 (EC 3.1.-.-)|
          Length = 661

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
 Frame = +2

Query: 179 YFLTHLHLDHTRGLGASGGWRHGP-------LYCSPATARLLPIRFP-GVDASLLRPVXX 334
           YFL+H H DH  GL  S  W +         LYCS  TA L+ ++F   +D   + P+  
Sbjct: 244 YFLSHFHSDHYIGLKKS--WNNPDENPIKKTLYCSKITAILVNLKFKIPMDEIQILPMNK 301

Query: 335 XXXXXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFR 448
                            +I V  L A HCPG+++ LF+
Sbjct: 302 RFWITD-----------TISVVTLDANHCPGAIIMLFQ 328

>DCR1A_CHICK (Q5QJC4) DNA cross-link repair 1A protein (chSNM1A)|
          Length = 972

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 1/94 (1%)
 Frame = +2

Query: 167 GSQVYFLTHLHLDHTRGLGASGGWRHGPLYCSPATARLLPIRFPGVDASL-LRPVXXXXX 343
           G   YFLTH H DH  GL  +  +   PLYC+  T  L+  +    +  + + P+     
Sbjct: 653 GCTAYFLTHFHSDHYCGLTKNFVF---PLYCNKITGNLVKSKLRVKEQYINVLPMDTECI 709

Query: 344 XXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLF 445
                          I V  L A HCPG+ M LF
Sbjct: 710 VN------------GIKVLLLDANHCPGATMILF 731

>Y514_SYNY3 (Q55470) Hypothetical protein sll0514|
          Length = 554

 Score = 34.3 bits (77), Expect = 0.17
 Identities = 31/104 (29%), Positives = 40/104 (38%), Gaps = 1/104 (0%)
 Frame = +2

Query: 164 GGSQVYFLTHLHLDHTRGLGA-SGGWRHGPLYCSPATARLLPIRFPGVDASLLRPVXXXX 340
           G   + F +H H DH  GL      + H P+  S  T RLLP+ +P         V    
Sbjct: 58  GTVDLVFCSHAHRDHGLGLWQFHQQFPHIPILASEVTQRLLPLNWPDEFVPPFCRVLPWR 117

Query: 341 XXXXXXXXPNSGRPVSIHVTALPALHCPGSLMFLFRSDIGCMLY 472
                   P    P  + V  LPA H PG+ + L     G  LY
Sbjct: 118 S-------PQEVLP-GLTVELLPAGHLPGAALILLEYHNGDRLY 153

>PHNP_ECOLI (P16692) Protein phnP|
          Length = 252

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 16/33 (48%), Positives = 23/33 (69%), Gaps = 2/33 (6%)
 Frame = +2

Query: 128 MDEGLVSV-DKFSGGS-QVYFLTHLHLDHTRGL 220
           +D GL  + D++S GS Q + LTH H+DH +GL
Sbjct: 53  IDAGLHDLADRWSPGSFQQFLLTHYHMDHVQGL 85

>LRFN2_MOUSE (Q80TG9) Leucine-rich repeat and fibronectin type-III|
           domain-containing protein 2 precursor
          Length = 788

 Score = 29.6 bits (65), Expect = 4.1
 Identities = 10/13 (76%), Positives = 11/13 (84%)
 Frame = -1

Query: 249 GPWRQPPDAPRPR 211
           GPWR PP APRP+
Sbjct: 639 GPWRLPPPAPRPK 651

>SHAN1_HUMAN (Q9Y566) SH3 and multiple ankyrin repeat domains protein 1 (Shank1)|
            (Somatostatin receptor-interacting protein)
            (SSTR-interacting protein) (SSTRIP)
          Length = 2161

 Score = 23.5 bits (49), Expect(2) = 7.9
 Identities = 10/13 (76%), Positives = 10/13 (76%)
 Frame = +2

Query: 212  RGLGASGGWRHGP 250
            R LGASGG R GP
Sbjct: 1760 RALGASGGLRPGP 1772



 Score = 23.5 bits (49), Expect(2) = 7.9
 Identities = 12/26 (46%), Positives = 15/26 (57%)
 Frame = +1

Query: 31   GLVSPIPFPLPRKTKTPPKIRGRRTG 108
            G  +P P P P +  TP K+RGR  G
Sbjct: 1739 GSSTPGP-PYPPQLMTPSKLRGRALG 1763


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,229,791
Number of Sequences: 219361
Number of extensions: 721217
Number of successful extensions: 2767
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 2610
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2740
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3130907202
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)