ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bast55d09 |
|---|---|
| Clone Library Name | barley_pub |
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 166 bits (421), Expect = 2e-41 Identities = 81/95 (85%), Positives = 90/95 (94%) Frame = +2 Query: 164 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 343 AMD + KLEKVGEGTYGKVY+A EK+TG+IVALKKTRL ED+EGVPPT LREVSLLRMLS Sbjct: 10 AMDAFVKLEKVGEGTYGKVYRAMEKSTGKIVALKKTRLHEDEEGVPPTTLREVSLLRMLS 69 Query: 344 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +DPHVVRLLD+KQGQNKEG+T+LYLVFEYMDTDLK Sbjct: 70 RDPHVVRLLDVKQGQNKEGKTVLYLVFEYMDTDLK 104
>CDC2C_ANTMA (Q38774) Cell division control protein 2 homolog C (EC 2.7.11.22)| (EC 2.7.11.23) Length = 305 Score = 133 bits (335), Expect = 2e-31 Identities = 69/95 (72%), Positives = 81/95 (85%), Gaps = 1/95 (1%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEKLEKVGEGTYGKVYKA EK+TG++VALKKTRL D+EGVPPTALREVSLL+MLSQ Sbjct: 1 MEKYEKLEKVGEGTYGKVYKALEKSTGQVVALKKTRLEMDEEGVPPTALREVSLLQMLSQ 60 Query: 347 DPHVVRLLDLKQGQ-NKEGQTILYLVFEYMDTDLK 448 +VVRLL ++ K G+ +LYLVFEY+DTDLK Sbjct: 61 SLYVVRLLSVEHVDCAKNGKPLLYLVFEYLDTDLK 95
>CDC2B_ARATH (P25859) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) Length = 309 Score = 124 bits (310), Expect = 2e-28 Identities = 64/99 (64%), Positives = 80/99 (80%), Gaps = 5/99 (5%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEKLEKVGEGTYGKVYKA EK TG++VALKKTRL D+EG+PPTALRE+SLL+MLS Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLST 60 Query: 347 DPHVVRLLDLK-----QGQNKEGQTILYLVFEYMDTDLK 448 +VVRLL ++ +++ ++ LYLVFEY+DTDLK Sbjct: 61 SIYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLK 99
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 107 bits (268), Expect = 1e-23 Identities = 59/91 (64%), Positives = 72/91 (79%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y+KLEK+GEGTYGKVYKA+EKATGR+VALKK RL +D+GVP TALRE+SLL+ + P+ Sbjct: 10 YQKLEKLGEGTYGKVYKAKEKATGRMVALKKIRL--EDDGVPSTALREISLLKEVPH-PN 66 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 VV L D+ QN+ LYLVFEY+D DLK Sbjct: 67 VVSLFDVLHCQNR-----LYLVFEYLDQDLK 92
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 105 bits (263), Expect = 4e-23 Identities = 54/94 (57%), Positives = 70/94 (74%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD YEK+EK+GEGTYG VYKAR+K T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ + + LYLVFEY+D DLK Sbjct: 60 HGNIVRLQDVVHSEKR-----LYLVFEYLDLDLK 88
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 105 bits (261), Expect = 7e-23 Identities = 53/94 (56%), Positives = 70/94 (74%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD YEK+EK+GEGTYG VYKAR+K T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V+L D+ + + LYLVFEY+D DLK Sbjct: 60 HSNIVKLQDVVHSEKR-----LYLVFEYLDLDLK 88
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 105 bits (261), Expect = 7e-23 Identities = 55/94 (58%), Positives = 71/94 (75%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L Q Sbjct: 1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKEL-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+VVRLLD+ ++K LYLVFE++ DLK Sbjct: 60 HPNVVRLLDVLMQESK-----LYLVFEFLSMDLK 88
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 104 bits (260), Expect = 1e-22 Identities = 53/94 (56%), Positives = 71/94 (75%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK+EK+GEGTYG VYKAR++AT +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ + + LYLVFEY+D DLK Sbjct: 60 HRNIVRLQDVVHSEKR-----LYLVFEYLDLDLK 88
>CDC2_SCHPO (P04551) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinse) Length = 297 Score = 103 bits (257), Expect = 2e-22 Identities = 53/97 (54%), Positives = 73/97 (75%), Gaps = 3/97 (3%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y+K+EK+GEGTYG VYKAR K +GRIVA+KK RL ++ EGVP TA+RE+SLL+ ++ Sbjct: 1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVND 60 Query: 347 D---PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 + + VRLLD+ ++K LYLVFE++D DLK Sbjct: 61 ENNRSNCVRLLDILHAESK-----LYLVFEFLDMDLK 92
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 103 bits (256), Expect = 3e-22 Identities = 52/94 (55%), Positives = 70/94 (74%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK+EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ + + LYLVFEY+D DLK Sbjct: 60 HRNIVRLQDVVHSEKR-----LYLVFEYLDLDLK 88
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 103 bits (256), Expect = 3e-22 Identities = 52/94 (55%), Positives = 70/94 (74%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK+EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ + + LYLVFEY+D DLK Sbjct: 60 HGNIVRLQDVVHSEKR-----LYLVFEYLDLDLK 88
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 102 bits (255), Expect = 4e-22 Identities = 53/94 (56%), Positives = 72/94 (76%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ ++K+EK+GEGTYG VYKAR + TG IVALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V+LLD+ +NK LYLVFE+++ DLK Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLNQDLK 88
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 102 bits (255), Expect = 4e-22 Identities = 53/94 (56%), Positives = 71/94 (75%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ ++K+EK+GEGTYG VYKAR K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V+LLD+ +NK LYLVFE++ DLK Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLHQDLK 88
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 102 bits (255), Expect = 4e-22 Identities = 52/94 (55%), Positives = 70/94 (74%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK+EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ + + LYLVFEY+D DLK Sbjct: 60 HRNIVRLQDVVHSEKR-----LYLVFEYLDLDLK 88
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 102 bits (254), Expect = 5e-22 Identities = 52/94 (55%), Positives = 72/94 (76%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD+++K+EK+GEGTYG VYKA+ + TG++VALKK RL + EGVP TA+RE+SLL+ L + Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++VRLLD+ + K LYLVFE++ DLK Sbjct: 60 HPNIVRLLDVVHNERK-----LYLVFEFLSQDLK 88
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 102 bits (254), Expect = 5e-22 Identities = 52/94 (55%), Positives = 70/94 (74%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD Y K+EK+GEGTYG VYK R KATG++VA+KK RL ++EGVP TA+RE+SLL+ L Q Sbjct: 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKEL-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V LLD+ ++ LYL+FE++ DLK Sbjct: 60 HPNIVCLLDVLMQDSR-----LYLIFEFLSMDLK 88
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 101 bits (252), Expect = 8e-22 Identities = 52/94 (55%), Positives = 71/94 (75%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V+LLD+ +NK LYLVFE++ DLK Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLHQDLK 88
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 101 bits (252), Expect = 8e-22 Identities = 52/94 (55%), Positives = 71/94 (75%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V+LLD+ +NK LYLVFE++ DLK Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLHQDLK 88
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 101 bits (252), Expect = 8e-22 Identities = 52/94 (55%), Positives = 71/94 (75%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V+LLD+ +NK LYLVFE++ DLK Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLHQDLK 88
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 101 bits (252), Expect = 8e-22 Identities = 52/94 (55%), Positives = 71/94 (75%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V+LLD+ +NK LYLVFE++ DLK Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFEFLHQDLK 88
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 101 bits (251), Expect = 1e-21 Identities = 52/94 (55%), Positives = 72/94 (76%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+VVRLLD+ +++ LYL+FE++ DLK Sbjct: 60 HPNVVRLLDVLMQESR-----LYLIFEFLSMDLK 88
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 101 bits (251), Expect = 1e-21 Identities = 52/94 (55%), Positives = 72/94 (76%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+VVRLLD+ +++ LYL+FE++ DLK Sbjct: 60 HPNVVRLLDVLMQESR-----LYLIFEFLSMDLK 88
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 101 bits (251), Expect = 1e-21 Identities = 52/94 (55%), Positives = 72/94 (76%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+VVRLLD+ +++ LYL+FE++ DLK Sbjct: 60 HPNVVRLLDVLMQESR-----LYLIFEFLSMDLK 88
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 101 bits (251), Expect = 1e-21 Identities = 52/94 (55%), Positives = 72/94 (76%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L + Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+VVRLLD+ +++ LYL+FE++ DLK Sbjct: 60 HPNVVRLLDVLMQESR-----LYLIFEFLSMDLK 88
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 101 bits (251), Expect = 1e-21 Identities = 51/94 (54%), Positives = 70/94 (74%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK+EK+GEGTYG VYKA +KAT +ALKK RL ++DEGVP TA+RE+SLL+ ++ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ + + +YLVFEY+D DLK Sbjct: 61 G-NIVRLHDVVHSEKR-----IYLVFEYLDLDLK 88
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 101 bits (251), Expect = 1e-21 Identities = 51/94 (54%), Positives = 72/94 (76%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD+++K+EK+GEGTYG VYKAR K TG++VALKK RL + EGVP TA+RE+SLL+ L + Sbjct: 1 MDVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++++LLD+ + K LY+VFE++ DLK Sbjct: 60 HPNIIKLLDVVHREKK-----LYMVFEFLTQDLK 88
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 101 bits (251), Expect = 1e-21 Identities = 51/94 (54%), Positives = 70/94 (74%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD Y K+EK+GEGTYG VYK R KATG++VA+KK RL ++EGVP TA+RE+SLL+ L Q Sbjct: 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKEL-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V LLD+ ++ LYL+FE++ D+K Sbjct: 60 HPNIVCLLDVLMQDSR-----LYLIFEFLSMDVK 88
>CDC2_EMENI (Q00646) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 323 Score = 100 bits (249), Expect = 2e-21 Identities = 54/95 (56%), Positives = 71/95 (74%), Gaps = 1/95 (1%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKA-TGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 343 M+ Y+K+EK+GEGTYG VYKARE RIVALKK RL +DEGVP TA+RE+SLL+ ++ Sbjct: 1 MENYQKIEKIGEGTYGVVYKARELTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMN 60 Query: 344 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 DP++VRLL++ + LYLVFE++D DLK Sbjct: 61 -DPNIVRLLNIVHADGHK----LYLVFEFLDLDLK 90
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 100 bits (248), Expect = 2e-21 Identities = 52/94 (55%), Positives = 70/94 (74%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V+LLD+ +NK LYLVFE + DLK Sbjct: 61 -PNIVKLLDVIHTENK-----LYLVFELLHQDLK 88
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 99.8 bits (247), Expect = 3e-21 Identities = 52/94 (55%), Positives = 69/94 (73%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD Y K+EK+GEGTYG VYK KATG+IVA+KK RL ++EGVP TA+RE+SLL+ L Q Sbjct: 1 MDEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKEL-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V LLD+ ++ LYL+FE++ DLK Sbjct: 60 HPNIVCLLDVLMQDSR-----LYLIFEFLSMDLK 88
>CDC2_AJECA (P54119) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 324 Score = 99.0 bits (245), Expect = 5e-21 Identities = 53/95 (55%), Positives = 70/95 (73%), Gaps = 1/95 (1%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKA-TGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 343 M+ Y+K+EK+GEGTYG VYKAR+ RIVALKK RL +DEGVP TA+RE+SLL+ + Sbjct: 1 MENYQKIEKIGEGTYGVVYKARDLTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEM- 59 Query: 344 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 DP++VRLL++ + LYLVFE++D DLK Sbjct: 60 HDPNIVRLLNIVHADGHK----LYLVFEFLDLDLK 90
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 98.6 bits (244), Expect = 7e-21 Identities = 50/94 (53%), Positives = 68/94 (72%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK EK+GEGTYG VY+AR+K T +ALKK RL ++DEGVP TA+RE+SLL+ + Sbjct: 1 MEQYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ + + +YLVFEY+D DLK Sbjct: 61 G-NIVRLHDVIHSEKR-----IYLVFEYLDLDLK 88
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 98.2 bits (243), Expect = 9e-21 Identities = 51/94 (54%), Positives = 69/94 (73%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ ++K+EK+GEGTYG VYKA+ K TG VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V+L D+ +NK LYLVFE++ DLK Sbjct: 61 -PNIVKLHDVIHTENK-----LYLVFEFLHQDLK 88
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 97.4 bits (241), Expect = 2e-20 Identities = 49/94 (52%), Positives = 69/94 (73%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ +EK+EK+GEGTYG VYK R + TG+IVA+KK RL DDEGVP TA+RE+SLL+ L Sbjct: 1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 + ++V L D+ +N+ +YL+FE++ DLK Sbjct: 61 E-NIVCLEDVLMEENR-----IYLIFEFLSMDLK 88
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 96.3 bits (238), Expect = 3e-20 Identities = 49/94 (52%), Positives = 67/94 (71%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK+EK+GEGTYG VYK + + T +ALKK RL ++DEGVP TA+RE+SLL+ + Q Sbjct: 1 MEQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-Q 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ + +YLVFEY+D DLK Sbjct: 60 HRNIVRLQDVVHKEK-----CIYLVFEYLDLDLK 88
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 95.9 bits (237), Expect = 5e-20 Identities = 48/94 (51%), Positives = 68/94 (72%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L + Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-R 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V L D+ ++ LYL+FE++ DLK Sbjct: 60 HPNIVSLQDVLMQDSR-----LYLIFEFLSMDLK 88
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 95.9 bits (237), Expect = 5e-20 Identities = 48/94 (51%), Positives = 68/94 (72%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L + Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-R 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V L D+ ++ LYL+FE++ DLK Sbjct: 60 HPNIVSLQDVLMQDSR-----LYLIFEFLSMDLK 88
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 95.9 bits (237), Expect = 5e-20 Identities = 49/90 (54%), Positives = 65/90 (72%) Frame = +2 Query: 179 EKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHV 358 E +EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ + Q ++ Sbjct: 2 ENVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-QHRNI 60 Query: 359 VRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 VRL D+ + LYLVFEY+D DLK Sbjct: 61 VRLQDVVHSDKR-----LYLVFEYLDLDLK 85
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 95.5 bits (236), Expect = 6e-20 Identities = 50/95 (52%), Positives = 68/95 (71%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D Y +++ +GEGTYG VY+A ++ATG+IVALKK RL DEG+P TALREVS+L+ + Sbjct: 21 DRYNRMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQEI-HH 79 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKSS 454 P++V LLD+ K LYL+FEY+D DLK + Sbjct: 80 PNIVNLLDVICADGK-----LYLIFEYVDHDLKKA 109
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 95.5 bits (236), Expect = 6e-20 Identities = 52/94 (55%), Positives = 68/94 (72%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG V KA+ + TG IVALK+ RL +DEGVP TA+RE+SLL+ L + Sbjct: 1 MEKYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++VRL D+ + K L LVFEY+D DLK Sbjct: 60 HPNIVRLHDVIHTERK-----LTLVFEYLDQDLK 88
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 94.4 bits (233), Expect = 1e-19 Identities = 48/94 (51%), Positives = 68/94 (72%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG VYK R + TG+IVA+KK RL ++EGVP TA+RE+SLL+ L + Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKEL-R 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V L D+ ++ LYL+FE++ DLK Sbjct: 60 HPNIVSLQDVLMQDSR-----LYLIFEFLSMDLK 88
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 94.4 bits (233), Expect = 1e-19 Identities = 47/94 (50%), Positives = 67/94 (71%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG VYK R K TG++V +KK RL ++EGVP TA+RE+SLL+ L + Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKEL-R 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V L D+ ++ LYL+FE++ DLK Sbjct: 60 HPNIVSLQDVLMQDSR-----LYLIFEFLSMDLK 88
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 94.4 bits (233), Expect = 1e-19 Identities = 48/94 (51%), Positives = 68/94 (72%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG VYK R + TG+IVA+KK RL ++EGVP TA+RE+SLL+ L + Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKEL-R 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V L D+ ++ LYL+FE++ DLK Sbjct: 60 HPNIVSLQDVLMQDSR-----LYLIFEFLSMDLK 88
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 93.6 bits (231), Expect = 2e-19 Identities = 48/94 (51%), Positives = 66/94 (70%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-H 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V L D+ + LYL+FE++ DLK Sbjct: 60 HPNIVCLQDVLMQDAR-----LYLIFEFLSMDLK 88
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 93.2 bits (230), Expect = 3e-19 Identities = 51/94 (54%), Positives = 65/94 (69%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ K L LVFE+ D DLK Sbjct: 60 HKNIVRLHDVLHSDKK-----LTLVFEFCDQDLK 88
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 93.2 bits (230), Expect = 3e-19 Identities = 51/94 (54%), Positives = 65/94 (69%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ K L LVFE+ D DLK Sbjct: 60 HKNIVRLHDVLHSDKK-----LTLVFEFCDQDLK 88
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 93.2 bits (230), Expect = 3e-19 Identities = 51/94 (54%), Positives = 65/94 (69%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ K L LVFE+ D DLK Sbjct: 60 HKNIVRLHDVLHSDKK-----LTLVFEFCDQDLK 88
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 93.2 bits (230), Expect = 3e-19 Identities = 51/94 (54%), Positives = 65/94 (69%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ K L LVFE+ D DLK Sbjct: 60 HKNIVRLHDVLHSDKK-----LTLVFEFCDQDLK 88
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 93.2 bits (230), Expect = 3e-19 Identities = 49/94 (52%), Positives = 68/94 (72%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 +D +++ EK+GEGTYG VYKAR +TG+ VALKK RL + EGVP TA+RE+SLL+ L + Sbjct: 5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL-K 63 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+VV+L D+ N LY++FEY++ DLK Sbjct: 64 HPNVVQLFDVVISGNN-----LYMIFEYLNMDLK 92
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 92.8 bits (229), Expect = 4e-19 Identities = 51/94 (54%), Positives = 65/94 (69%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ K L LVFE+ D DLK Sbjct: 60 HKNIVRLHDVLHSDKK-----LTLVFEFCDQDLK 88
>CDC28_YEAST (P00546) Cell division control protein 28 (EC 2.7.11.22)| Length = 298 Score = 92.8 bits (229), Expect = 4e-19 Identities = 52/94 (55%), Positives = 67/94 (71%), Gaps = 3/94 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATG---RIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 Y++LEKVGEGTYG VYKA + G R+VALKK RL +DEGVP TA+RE+SLL+ L + Sbjct: 8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKEL-K 66 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 D ++VRL D+ + LYLVFE++D DLK Sbjct: 67 DDNIVRLYDIVHSDAHK----LYLVFEFLDLDLK 96
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 92.8 bits (229), Expect = 4e-19 Identities = 50/94 (53%), Positives = 65/94 (69%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M Y+K+EK+GEGTYG V+K R + T IVALK+ RL EDDEGVP +ALRE+ LL+ L + Sbjct: 1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL+D+ K L LVFE+ D DLK Sbjct: 60 HKNIVRLIDVLHSDKK-----LTLVFEHCDQDLK 88
>CDC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.11.22)| Length = 317 Score = 92.0 bits (227), Expect = 7e-19 Identities = 50/92 (54%), Positives = 67/92 (72%), Gaps = 1/92 (1%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKARE-KATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 352 Y++ EKVGEGTYG VYKA + K R+VALKK RL +DEGVP TA+RE+SLL+ + +D Sbjct: 7 YQRQEKVGEGTYGVVYKALDTKHNNRVVALKKIRLESEDEGVPSTAIREISLLKEM-KDD 65 Query: 353 HVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++VRL D+ + + LYLVFE++D DLK Sbjct: 66 NIVRLYDIIHSDSHK----LYLVFEFLDLDLK 93
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 91.3 bits (225), Expect = 1e-18 Identities = 47/91 (51%), Positives = 67/91 (73%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE+ EK+GEGTYG VYKAR+ +T VALK+ RL ++EGVP TA+RE+SLL+ L + + Sbjct: 5 YERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHE-N 63 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +V+LLD+ +++ L +VFEY+D DLK Sbjct: 64 IVKLLDVCHSEHR-----LTIVFEYLDLDLK 89
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 90.1 bits (222), Expect = 2e-18 Identities = 48/91 (52%), Positives = 67/91 (73%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y++LEK+GEG+YG VY+AR+ T IVALK+ RL +EGVP TA+RE+S+L+ L + + Sbjct: 5 YQRLEKIGEGSYGVVYRARDITTDVIVALKRIRLESVEEGVPCTAIREISILKELRHE-N 63 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +VRLLD+ +N+ L LVFEYM+ DLK Sbjct: 64 IVRLLDVCHSENR-----LNLVFEYMEMDLK 89
>CC2H2_TRYBB (P54665) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 345 Score = 89.0 bits (219), Expect = 6e-18 Identities = 50/93 (53%), Positives = 65/93 (69%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D Y ++EKVGEG+YG VYK + TGR VA+K+ L +D GVP TA+REVSLLR L+ Sbjct: 44 DRYSRIEKVGEGSYGIVYKCHDNFTGRTVAMKRIPLIVNDGGVPSTAVREVSLLRELNH- 102 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+VVRLLD+ + K L L+FEYM+ DL+ Sbjct: 103 PYVVRLLDVVLHEAK-----LLLIFEYMEQDLQ 130
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 87.8 bits (216), Expect = 1e-17 Identities = 45/91 (49%), Positives = 68/91 (74%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE+L+K+GEG+YG V++AR+ TG IVA+K+ RL +++EGVP TA+RE+S+L+ L + + Sbjct: 5 YERLQKIGEGSYGVVFRARDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKELRHE-N 63 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +VRLLD+ + + L LVFE M+ DLK Sbjct: 64 IVRLLDVCHSEKR-----LTLVFECMEMDLK 89
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 87.0 bits (214), Expect = 2e-17 Identities = 47/91 (51%), Positives = 65/91 (71%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y++LEK+GEGTY VYK + + TG IVALK R+ + DEG P TA+RE+SL++ L + P+ Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRI-DADEGTPSTAIREISLMKEL-RHPN 60 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++ L D+ Q +NK L LVFEYM+ DLK Sbjct: 61 IMSLSDVLQTENK-----LMLVFEYMEKDLK 86
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 87.0 bits (214), Expect = 2e-17 Identities = 46/91 (50%), Positives = 64/91 (70%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 + KLEK+GEGTYG VYK + + T +VA+KK RL +DEGVP TA+RE+SLL+ L Q P+ Sbjct: 22 FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKEL-QHPN 80 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 VV L + +N+ L+L+FE++ DLK Sbjct: 81 VVGLEAVIMQENR-----LFLIFEFLSFDLK 106
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 86.3 bits (212), Expect = 4e-17 Identities = 49/94 (52%), Positives = 63/94 (67%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M Y K+EK+GEGTYG VYKA+ G I ALKK R+ E+DEG+P TA+RE+SLL+ L Sbjct: 1 MRRYHKMEKIGEGTYGVVYKAQNNH-GEICALKKIRVEEEDEGIPSTAIREISLLKEL-H 58 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V L D+ + L LVFEY+D DLK Sbjct: 59 HPNIVWLRDVIHSEK-----CLTLVFEYLDQDLK 87
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 86.3 bits (212), Expect = 4e-17 Identities = 49/94 (52%), Positives = 63/94 (67%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M Y K+EK+GEGTYG VYKA+ G I ALKK R+ E+DEG+P TA+RE+SLL+ L Sbjct: 1 MRRYHKMEKIGEGTYGVVYKAQNNH-GEICALKKIRVEEEDEGIPSTAIREISLLKEL-H 58 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P++V L D+ + L LVFEY+D DLK Sbjct: 59 HPNIVWLRDVIHSEK-----CLTLVFEYLDQDLK 87
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 84.7 bits (208), Expect = 1e-16 Identities = 44/100 (44%), Positives = 65/100 (65%), Gaps = 5/100 (5%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R +D ++ + +GEGTYG+VYKAR+K TG +VALKK RL + EG P TA+RE+ +LR L Sbjct: 700 RCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQL 759 Query: 341 SQDPHVVRLLDLKQGQN-----KEGQTILYLVFEYMDTDL 445 + ++ + ++ + K+ + YLVFEYMD DL Sbjct: 760 THQ-SIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDL 798
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 84.7 bits (208), Expect = 1e-16 Identities = 44/100 (44%), Positives = 65/100 (65%), Gaps = 5/100 (5%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R +D ++ + +GEGTYG+VYKAR+K TG +VALKK RL + EG P TA+RE+ +LR L Sbjct: 700 RCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQL 759 Query: 341 SQDPHVVRLLDLKQGQN-----KEGQTILYLVFEYMDTDL 445 + ++ + ++ + K+ + YLVFEYMD DL Sbjct: 760 THQ-SIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDL 798
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 84.3 bits (207), Expect = 1e-16 Identities = 46/91 (50%), Positives = 64/91 (70%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +++LEK+GEGTY VYK R +ATG +VALK+ L + +EG P TA+RE+SL++ L + + Sbjct: 8 FQQLEKLGEGTYATVYKGRNRATGALVALKEISL-DSEEGTPSTAIREISLMKELDHE-N 65 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +V L D+ +NK L LVFEYMD DLK Sbjct: 66 IVTLYDVIHTENK-----LTLVFEYMDKDLK 91
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 84.0 bits (206), Expect = 2e-16 Identities = 46/100 (46%), Positives = 64/100 (64%), Gaps = 5/100 (5%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R +D ++ + +GEGTYG+VYKAR+K TG +VALKK RL + EG P TA+RE+ +LR L Sbjct: 722 RCVDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQL 781 Query: 341 SQDPHVVRLLDLKQGQN-----KEGQTILYLVFEYMDTDL 445 VV + ++ + K+ + YLVFEYMD DL Sbjct: 782 IH-RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDL 820
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 84.0 bits (206), Expect = 2e-16 Identities = 45/91 (49%), Positives = 64/91 (70%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +++LEK+GEGTY VYK R + TG++VALK+ L + +EG P TA+RE+SL++ L + + Sbjct: 7 FQQLEKLGEGTYATVYKGRNRTTGQLVALKEINL-DSEEGTPSTAIREISLMKELKHE-N 64 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +V L D+ +NK L LVFEYMD DLK Sbjct: 65 IVTLYDVIHTENK-----LNLVFEYMDKDLK 90
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 83.2 bits (204), Expect = 3e-16 Identities = 46/91 (50%), Positives = 63/91 (69%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +++LEK+G GTY VYK K+TG VALK+ +L + +EG P TA+RE+SL++ L D + Sbjct: 6 FKQLEKLGNGTYATVYKGLNKSTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHD-N 63 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +VRL D+ +NK L LVFEYMD DLK Sbjct: 64 IVRLYDVIHTENK-----LTLVFEYMDNDLK 89
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 82.8 bits (203), Expect = 4e-16 Identities = 46/91 (50%), Positives = 62/91 (68%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +++LEKVG GTY VYK K TG VALK+ +L + +EG P TA+RE+SL++ L D + Sbjct: 7 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHD-N 64 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +VRL D+ +NK L LVFE+MD DLK Sbjct: 65 IVRLFDVIHTENK-----LTLVFEFMDNDLK 90
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 82.4 bits (202), Expect = 5e-16 Identities = 45/94 (47%), Positives = 65/94 (69%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y LEK+GEGTYG VYKA + + G ALKK RL ++DEG+P TA+RE+S+L+ L + Sbjct: 1 MEKYHGLEKIGEGTYGVVYKA-QNSDGESFALKKIRLEKEDEGIPSTAIREISILKEL-R 58 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V+L D+ + + L LVFE++D DLK Sbjct: 59 HSNIVKLYDVIHAKKR-----LILVFEHLDQDLK 87
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 82.4 bits (202), Expect = 5e-16 Identities = 45/94 (47%), Positives = 65/94 (69%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y LEK+GEGTYG VYKA + + G ALKK RL ++DEG+P TA+RE+S+L+ L + Sbjct: 1 MEKYHGLEKIGEGTYGVVYKA-QNSDGESFALKKIRLEKEDEGIPSTAIREISILKEL-R 58 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V+L D+ + + L LVFE++D DLK Sbjct: 59 HSNIVKLYDVIHAKKR-----LILVFEHLDQDLK 87
>CDK6_MOUSE (Q64261) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) (CRK2) Length = 326 Score = 82.0 bits (201), Expect = 7e-16 Identities = 46/98 (46%), Positives = 66/98 (67%), Gaps = 3/98 (3%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKARE-KATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 337 RA YE + ++GEG YGKV+KAR+ K GR VALK+ R+ +EG+P + +REV++LR Sbjct: 8 RADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIREVAVLRH 67 Query: 338 LS--QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 L + P+VVRL D+ + +T L LVFE++D DL Sbjct: 68 LETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDL 105
>CDK6_HUMAN (Q00534) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) Length = 326 Score = 81.6 bits (200), Expect = 9e-16 Identities = 46/98 (46%), Positives = 66/98 (67%), Gaps = 3/98 (3%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKARE-KATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 337 RA YE + ++GEG YGKV+KAR+ K GR VALK+ R+ +EG+P + +REV++LR Sbjct: 8 RADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRH 67 Query: 338 LS--QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 L + P+VVRL D+ + +T L LVFE++D DL Sbjct: 68 LETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDL 105
>CD2L7_CAEEL (P46551) Putative cell division cycle 2-related protein kinase 7| (EC 2.7.11.22) Length = 730 Score = 81.6 bits (200), Expect = 9e-16 Identities = 44/95 (46%), Positives = 60/95 (63%), Gaps = 5/95 (5%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y L+++GEGTYG+VYKA TG VALK+ RL + EG P TA+RE+ +LR L + Sbjct: 311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQL-HHKN 369 Query: 356 VVRLL-----DLKQGQNKEGQTILYLVFEYMDTDL 445 +VRL+ D+ + K + YLVFEY+D DL Sbjct: 370 IVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDL 404
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 81.3 bits (199), Expect = 1e-15 Identities = 45/94 (47%), Positives = 63/94 (67%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P TA+RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTAIREISILKELKH 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V+L D+ + + L LVFE++D DLK Sbjct: 60 S-NIVKLYDVIHTKKR-----LILVFEHLDQDLK 87
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 81.3 bits (199), Expect = 1e-15 Identities = 45/94 (47%), Positives = 63/94 (67%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P TA+RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTAIREISILKELKH 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V+L D+ + + L LVFE++D DLK Sbjct: 60 S-NIVKLYDVIHTKKR-----LILVFEHLDQDLK 87
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 80.5 bits (197), Expect = 2e-15 Identities = 43/91 (47%), Positives = 63/91 (69%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +++LEK+GEGTY VYK R + G++VALK+ L + +EG P TA+RE+SL++ L + + Sbjct: 8 FQQLEKLGEGTYATVYKGRNRTNGQLVALKEINL-DSEEGTPSTAIREISLMKELDHE-N 65 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +V L D+ +NK L LVFE+MD DLK Sbjct: 66 IVTLYDVIHTENK-----LTLVFEFMDKDLK 91
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 80.1 bits (196), Expect = 3e-15 Identities = 49/94 (52%), Positives = 61/94 (64%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y KLEK+GEGTY VYK R K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKDL-K 246 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V L D+ L LVFEY+D DLK Sbjct: 247 HANIVTLHDIVHTDKS-----LTLVFEYLDKDLK 275
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 80.1 bits (196), Expect = 3e-15 Identities = 49/94 (52%), Positives = 61/94 (64%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y KLEK+GEGTY VYK R K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKDL-K 246 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V L D+ L LVFEY+D DLK Sbjct: 247 HANIVTLHDIVHTDKS-----LTLVFEYLDKDLK 275
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 80.1 bits (196), Expect = 3e-15 Identities = 49/94 (52%), Positives = 61/94 (64%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y KLEK+GEGTY VYK R K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKDL-K 246 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V L D+ L LVFEY+D DLK Sbjct: 247 HANIVTLHDIVHTDKS-----LTLVFEYLDKDLK 275
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 79.7 bits (195), Expect = 3e-15 Identities = 44/94 (46%), Positives = 62/94 (65%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P T +RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTTIREISILKELKH 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V+L D+ + + L LVFE++D DLK Sbjct: 60 S-NIVKLYDVIHTKKR-----LVLVFEHLDQDLK 87
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 79.7 bits (195), Expect = 3e-15 Identities = 44/94 (46%), Positives = 62/94 (65%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P T +RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTTIREISILKELKH 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V+L D+ + + L LVFE++D DLK Sbjct: 60 S-NIVKLYDVIHTKKR-----LVLVFEHLDQDLK 87
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 79.7 bits (195), Expect = 3e-15 Identities = 44/91 (48%), Positives = 62/91 (68%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +++LEK+G GTY VYK K TG VALK+ +L + +EG P TA+RE+SL++ L + + Sbjct: 7 FKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHE-N 64 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +VRL D+ +NK L LVFE+MD DLK Sbjct: 65 IVRLYDVIHTENK-----LTLVFEFMDNDLK 90
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 79.3 bits (194), Expect = 4e-15 Identities = 53/122 (43%), Positives = 69/122 (56%), Gaps = 7/122 (5%) Frame = +2 Query: 104 LQHQNQGAAAPMXXXXXXLRAMDL-------YEKLEKVGEGTYGKVYKAREKATGRIVAL 262 LQ +N G P+ D+ Y KL+K+GEGTY V+K R K T +VAL Sbjct: 90 LQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVAL 149 Query: 263 KKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTD 442 K+ RL E +EG P TA+REVSLL+ L + ++V L DL L LVFEY+D+D Sbjct: 150 KEIRL-EHEEGAPCTAIREVSLLKDL-KHANIVTLHDLIHTDRS-----LTLVFEYLDSD 202 Query: 443 LK 448 LK Sbjct: 203 LK 204
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 79.3 bits (194), Expect = 4e-15 Identities = 53/122 (43%), Positives = 69/122 (56%), Gaps = 7/122 (5%) Frame = +2 Query: 104 LQHQNQGAAAPMXXXXXXLRAMDL-------YEKLEKVGEGTYGKVYKAREKATGRIVAL 262 LQ +N G P+ D+ Y KL+K+GEGTY V+K R K T +VAL Sbjct: 90 LQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVAL 149 Query: 263 KKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTD 442 K+ RL E +EG P TA+REVSLL+ L + ++V L DL L LVFEY+D+D Sbjct: 150 KEIRL-EHEEGAPCTAIREVSLLKDL-KHANIVTLHDLIHTDRS-----LTLVFEYLDSD 202 Query: 443 LK 448 LK Sbjct: 203 LK 204
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 79.0 bits (193), Expect = 6e-15 Identities = 43/91 (47%), Positives = 62/91 (68%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +++LE++G GTY VYK K TG VALK+ +L + +EG P TA+RE+SL++ L + + Sbjct: 9 FKQLERLGNGTYATVYKGLNKTTGLYVALKEVKL-DSEEGTPSTAIREISLMKELKHE-N 66 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 +VRL D+ +NK L LVFE+MD DLK Sbjct: 67 IVRLYDVIHTENK-----LTLVFEFMDNDLK 92
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 78.6 bits (192), Expect = 8e-15 Identities = 41/97 (42%), Positives = 66/97 (68%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R++ +EKL ++GEGTYG VY+AR+ T IVALKK R+ ++ +G+P ++LRE++LL L Sbjct: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL 93 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 + P++V L ++ G + E ++LV Y + DL S Sbjct: 94 -RHPNIVELKEVVVGNHLES---IFLVMGYCEQDLAS 126
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 78.2 bits (191), Expect = 1e-14 Identities = 47/94 (50%), Positives = 62/94 (65%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 ++ Y KL+K+GEGTY V+K R K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKNL-K 196 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V L DL L LVFEY+D+DLK Sbjct: 197 HANIVTLHDLIHTDRS-----LTLVFEYLDSDLK 225
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 78.2 bits (191), Expect = 1e-14 Identities = 38/94 (40%), Positives = 63/94 (67%), Gaps = 2/94 (2%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS--QD 349 YE + ++G G YG VYKAR+ +G+ VALK R+ ++ G+P + +REV+LL+ L Sbjct: 9 YEPVAEIGVGAYGTVYKARDLQSGKFVALKNVRVQTNENGLPLSTVREVTLLKRLEHFDH 68 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 P++V+L+D+ + +T + LVFE++D DLK+ Sbjct: 69 PNIVKLMDVCASARTDRETKVTLVFEHVDQDLKT 102
>CDK9_HUMAN (P50750) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4) Length = 372 Score = 77.8 bits (190), Expect = 1e-14 Identities = 40/93 (43%), Positives = 63/93 (67%), Gaps = 3/93 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YEKL K+G+GT+G+V+KAR + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 356 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDL 445 VV L+++ K + +YLVF++ + DL Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDL 110
>CTK1_YEAST (Q03957) CTD kinase subunit alpha (EC 2.7.11.23) (CTD kinase 58 kDa| subunit) (CTDK-I alpha subunit) Length = 528 Score = 77.8 bits (190), Expect = 1e-14 Identities = 41/95 (43%), Positives = 61/95 (64%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R+ +Y ++ +VGEGTYGKVYKA+ T ++VALKK RL + EG P T++RE+ LL+ Sbjct: 178 RSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSF 237 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 P+V + ++ E Q +Y++FEY D DL Sbjct: 238 DH-PNVSTIKEIM----VESQKTVYMIFEYADNDL 267
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 77.8 bits (190), Expect = 1e-14 Identities = 47/105 (44%), Positives = 64/105 (60%) Frame = +2 Query: 134 PMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTAL 313 P+ ++ Y KL+K+GEGTY VYK + K T +VALK+ RL E +EG P TA+ Sbjct: 151 PVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAI 209 Query: 314 REVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 REVSLL+ L + ++V L D+ + L LVFEY+D DLK Sbjct: 210 REVSLLKDL-KHANIVTLHDIIHTEKS-----LTLVFEYLDKDLK 248
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 77.4 bits (189), Expect = 2e-14 Identities = 46/94 (48%), Positives = 62/94 (65%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 ++ Y KL+K+GEGTY VYK + K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAIREVSLLKDL-K 219 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V L D+ + L LVFEY+D DLK Sbjct: 220 HANIVTLHDIIHTEKS-----LTLVFEYLDKDLK 248
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 77.4 bits (189), Expect = 2e-14 Identities = 46/94 (48%), Positives = 62/94 (65%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 ++ Y KL+K+GEGTY VYK + K T +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAIREVSLLKDL-K 219 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V L D+ + L LVFEY+D DLK Sbjct: 220 HANIVTLHDIIHTEKS-----LTLVFEYLDKDLK 248
>CDK9_CHICK (Q5ZKN1) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 77.0 bits (188), Expect = 2e-14 Identities = 39/93 (41%), Positives = 63/93 (67%), Gaps = 3/93 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 356 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDL 445 VV L+++ K + +YLVF++ + DL Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDL 110
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 76.6 bits (187), Expect = 3e-14 Identities = 45/97 (46%), Positives = 63/97 (64%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R D Y K E +GEGTYG V+KA + TG VA+KK RL + EGV TALRE+ LL+ L Sbjct: 14 RVADRYLKREVLGEGTYGVVFKAVDTKTGNTVAIKKIRLGKYKEGVNFTALREIKLLKEL 73 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 +D +++ L+D + L+LVFE+M+TDL++ Sbjct: 74 -KDSNIIELIDAFPYKGN-----LHLVFEFMETDLEA 104
>CDK9_RAT (Q641Z4) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 76.6 bits (187), Expect = 3e-14 Identities = 39/93 (41%), Positives = 63/93 (67%), Gaps = 3/93 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 356 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDL 445 VV L+++ K + +YLVF++ + DL Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDL 110
>CDK9_MOUSE (Q99J95) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 76.6 bits (187), Expect = 3e-14 Identities = 39/93 (41%), Positives = 63/93 (67%), Gaps = 3/93 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 356 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDL 445 VV L+++ K + +YLVF++ + DL Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDL 110
>CDK9_BOVIN (Q5EAB2) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 76.6 bits (187), Expect = 3e-14 Identities = 39/93 (41%), Positives = 63/93 (67%), Gaps = 3/93 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 356 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDL 445 VV L+++ K + +YLVF++ + DL Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDL 110
>YP62_CAEEL (Q09437) Putative serine/threonine-protein kinase B0495.2 (EC| 2.7.11.1) Length = 719 Score = 76.6 bits (187), Expect = 3e-14 Identities = 36/97 (37%), Positives = 63/97 (64%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R +D YE + +V EGT+G VY+ ++K T IVALK+ ++ ++ EG P TALRE+++L Sbjct: 351 RNIDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKA 410 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 P++V + ++ G N + +Y+ E+++ D+KS Sbjct: 411 GNHPNIVNVKEILLGSNMDK---IYMAMEFVEHDMKS 444
>CDC21_PEA (P19026) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34) (Fragment) Length = 148 Score = 76.6 bits (187), Expect = 3e-14 Identities = 40/77 (51%), Positives = 55/77 (71%) Frame = +2 Query: 218 VYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQNKE 397 VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ + Q ++VRL D+ + + Sbjct: 2 VYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM-QHRNIVRLQDVVHSEKR- 59 Query: 398 GQTILYLVFEYMDTDLK 448 LYLVFEY+D DLK Sbjct: 60 ----LYLVFEYLDLDLK 72
>BUR1_EMENI (Q96VK3) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) (Pitalre-like kinase A) Length = 544 Score = 76.6 bits (187), Expect = 3e-14 Identities = 44/93 (47%), Positives = 65/93 (69%), Gaps = 3/93 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +E L K+GEGT+G+VYKAR K G IVALKK + + +G P TALRE+ LL+MLS + Sbjct: 25 FEFLGKLGEGTFGEVYKARAKRDGSIVALKKILMHNERDGFPITALREIKLLKMLSH-TN 83 Query: 356 VVRLLDLKQGQNK-EG--QTILYLVFEYMDTDL 445 +++L ++ ++K EG + +Y+VF YM+ DL Sbjct: 84 IMQLREMAVERSKGEGRKKPSMYMVFPYMEHDL 116
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 76.6 bits (187), Expect = 3e-14 Identities = 44/95 (46%), Positives = 65/95 (68%), Gaps = 1/95 (1%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPT-ALREVSLLRMLS 343 M+ Y LEK+GEGTYG VYKA + + G ALKK RL ++DEG+P T ++RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKA-QNSDGESFALKKIRLEKEDEGIPSTVSIREISILKEL- 58 Query: 344 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 + ++V+L D+ + + L LVFE++D DLK Sbjct: 59 RHSNIVKLYDVIHAKKR-----LILVFEHLDQDLK 88
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 75.9 bits (185), Expect = 5e-14 Identities = 46/94 (48%), Positives = 61/94 (64%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 ++ Y KL+K+GEGTY V+K R K +VALK+ RL E +EG P TA+REVSLL+ L + Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLMENLVALKEIRL-EHEEGAPCTAIREVSLLKNL-K 196 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++V L DL L LVFEY+D+DLK Sbjct: 197 HANIVTLHDLIHTDRS-----LTLVFEYLDSDLK 225
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 75.9 bits (185), Expect = 5e-14 Identities = 41/93 (44%), Positives = 63/93 (67%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEKL K+GEG+YG V+K R K++G++VA+KK EDD V ALRE+ +L+ L + Sbjct: 1 MEKYEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 P++V L+++ + + K ++LVFEY D L Sbjct: 60 HPNLVNLIEVFRRKRK-----MHLVFEYCDHTL 87
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 75.9 bits (185), Expect = 5e-14 Identities = 41/90 (45%), Positives = 61/90 (67%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK+ K+GEG+YG V+K R K TG+IVA+KK EDD + ALRE+ +L+ L + Sbjct: 1 MEKYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 P++V L+++ + + K L+LVFEY D Sbjct: 60 HPNLVNLMEVFRRKRK-----LHLVFEYCD 84
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 75.5 bits (184), Expect = 6e-14 Identities = 45/92 (48%), Positives = 61/92 (66%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D YEKLEK+GEG+Y VYK + K G++VALK RL +++EG P TA+RE SLL+ L + Sbjct: 133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRL-QEEEGTPFTAIREASLLKGL-KH 190 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 ++V L D+ + L LVFEY+ TDL Sbjct: 191 ANIVLLHDIIHTKE-----TLTLVFEYVHTDL 217
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 75.5 bits (184), Expect = 6e-14 Identities = 45/92 (48%), Positives = 61/92 (66%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D YEKLEK+GEG+Y VYK + K G++VALK RL +++EG P TA+RE SLL+ L + Sbjct: 133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRL-QEEEGTPFTAIREASLLKGL-KH 190 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 ++V L D+ + L LVFEY+ TDL Sbjct: 191 ANIVLLHDIIHTKE-----TLTLVFEYVHTDL 217
>BUR1_NEUCR (Q871M9) Serine/threonine-protein kinase bur-1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 545 Score = 75.1 bits (183), Expect = 8e-14 Identities = 42/94 (44%), Positives = 63/94 (67%), Gaps = 4/94 (4%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE L K+GEGT+G+V++AR + TG +VALKK + + +G P TALRE+ LL++LS + Sbjct: 26 YEVLGKLGEGTFGEVHRARSRKTGALVALKKIIMHNERDGFPITALREIKLLKLLSH-KN 84 Query: 356 VVRL----LDLKQGQNKEGQTILYLVFEYMDTDL 445 V+RL ++ +K + I+Y+V YMD DL Sbjct: 85 VLRLEEMAIEHPPRTDKRTRPIVYMVTPYMDHDL 118
>KP58_DROME (Q9VPC0) Serine/threonine-protein kinase PITSLRE (EC 2.7.11.22)| (Cell division cycle 2-like) Length = 952 Score = 74.7 bits (182), Expect = 1e-13 Identities = 36/97 (37%), Positives = 67/97 (69%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ L + Sbjct: 553 RSVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTL-LK 611 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 Q P++V + ++ G N + +++V +Y++ DLKS Sbjct: 612 GQHPNIVTVREIVVGSNMDK---IFIVMDYVEHDLKS 645
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 74.7 bits (182), Expect = 1e-13 Identities = 40/80 (50%), Positives = 55/80 (68%) Frame = +2 Query: 209 YGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQ 388 YG VYKAR+ T +ALKK RL ++DEGVP TA+RE+SLL+ + + ++V L D+ + Sbjct: 2 YGVVYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHE-NIVNLKDVVHRE 60 Query: 389 NKEGQTILYLVFEYMDTDLK 448 + LYLVFEY+D DLK Sbjct: 61 KR-----LYLVFEYLDLDLK 75
>CD2L1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1) Length = 795 Score = 74.7 bits (182), Expect = 1e-13 Identities = 36/97 (37%), Positives = 67/97 (69%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ + + Sbjct: 433 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTI-LK 491 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 +Q P++V + ++ G N + +Y+V Y++ DLKS Sbjct: 492 AQHPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKS 525
>CD2L1_MOUSE (P24788) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 784 Score = 74.7 bits (182), Expect = 1e-13 Identities = 36/97 (37%), Positives = 67/97 (69%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ + + Sbjct: 422 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTI-LK 480 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 +Q P++V + ++ G N + +Y+V Y++ DLKS Sbjct: 481 AQHPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKS 514
>CDK4_PIG (P79432) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 303 Score = 74.7 bits (182), Expect = 1e-13 Identities = 42/101 (41%), Positives = 63/101 (62%), Gaps = 5/101 (4%) Frame = +2 Query: 164 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPED---DEGVPPTALREVSLLR 334 A YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR Sbjct: 2 ATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALLR 61 Query: 335 MLS--QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 L + P+VVRL+D+ + +T + LVFE++D DL++ Sbjct: 62 RLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRT 102
>BUR1_YARLI (Q6C842) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 706 Score = 74.7 bits (182), Expect = 1e-13 Identities = 41/93 (44%), Positives = 63/93 (67%), Gaps = 3/93 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y+ L K+GEGT+G+V++A + T R VALKK L + EG P TALRE+ +L++L + + Sbjct: 38 YKPLGKIGEGTFGEVFRAEQITTKRHVALKKILLHSEKEGFPVTALREIRILKLLRHE-N 96 Query: 356 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDL 445 V+ L+DL + Q+K+ + +Y+V YMD DL Sbjct: 97 VIPLVDLAVERGDQSKKERGCVYMVTPYMDHDL 129
>CD2L2_HUMAN (Q9UQ88) PITSLRE serine/threonine-protein kinase CDC2L2 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11) Length = 780 Score = 74.7 bits (182), Expect = 1e-13 Identities = 36/97 (37%), Positives = 67/97 (69%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ + + Sbjct: 418 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTI-LK 476 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 +Q P++V + ++ G N + +Y+V Y++ DLKS Sbjct: 477 AQHPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKS 510
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 74.3 bits (181), Expect = 1e-13 Identities = 40/90 (44%), Positives = 61/90 (67%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK+ K+GEG+YG V+K R + TG+IVA+KK EDD + ALRE+ +L+ L + Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 P++V LL++ + + + L+LVFEY D Sbjct: 60 HPNLVNLLEVFRRKRR-----LHLVFEYCD 84
>BUR1_GIBZE (Q4I5U9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 473 Score = 74.3 bits (181), Expect = 1e-13 Identities = 41/95 (43%), Positives = 63/95 (66%), Gaps = 5/95 (5%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE L K+GEGT+G+V++AR + TG +VALKK + + +G P TALRE+ LL++LS + Sbjct: 37 YELLGKLGEGTFGEVHRARLRKTGALVALKKIIMHHEKDGFPITALREIKLLKLLSH-KN 95 Query: 356 VVRLLDL-----KQGQNKEGQTILYLVFEYMDTDL 445 ++RL D+ + +K + I+Y+ YMD DL Sbjct: 96 ILRLEDMAIEHPTRQTDKRKKPIVYMATPYMDHDL 130
>CD2L1_RAT (P46892) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 436 Score = 73.9 bits (180), Expect = 2e-13 Identities = 35/97 (36%), Positives = 67/97 (69%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T++RE++ + + Sbjct: 74 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPLTSIREINTI-LK 132 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 +Q P++V + ++ G N + +Y+V Y++ DLKS Sbjct: 133 AQHPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKS 166
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 73.9 bits (180), Expect = 2e-13 Identities = 41/93 (44%), Positives = 61/93 (65%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEKL K GEG+YG V+K R K +G++VA+KK EDD V ALRE+ +L+ L + Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 P++V L+++ + + K ++LVFEY D L Sbjct: 60 HPNLVNLIEVFRRKRK-----MHLVFEYCDHTL 87
>CDK9_CAEEL (Q9TVL3) Probable cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 478 Score = 73.6 bits (179), Expect = 2e-13 Identities = 41/101 (40%), Positives = 62/101 (61%), Gaps = 5/101 (4%) Frame = +2 Query: 158 LRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 337 +R + YEKL K+G+GT+G+V+KAR K TGR+VALKK + + EG P TALREV +L Sbjct: 79 IRDVSTYEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQ 138 Query: 338 LSQDPHVVRLLDLKQGQN-----KEGQTILYLVFEYMDTDL 445 L + P++ L+++ ++ + + YLV DL Sbjct: 139 L-KHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDL 178
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 73.2 bits (178), Expect = 3e-13 Identities = 39/90 (43%), Positives = 61/90 (67%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK+ K+GEG+YG V+K R + TG+IVA+K+ EDD + ALRE+ +L+ L + Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 P++V LL++ + + + L+LVFEY D Sbjct: 60 HPNLVNLLEVFRRKRR-----LHLVFEYCD 84
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 73.2 bits (178), Expect = 3e-13 Identities = 43/94 (45%), Positives = 64/94 (68%), Gaps = 3/94 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLSQ 346 YEKL+ +GEG + VYKAR+K T RIVA+KK +L E ++G+ TALRE+ LL+ LS Sbjct: 18 YEKLDFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEANDGINRTALREIKLLQELSH 77 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+++ LLD ++ + LVF++M+TDL+ Sbjct: 78 -PNIIGLLDAFGHKSN-----ISLVFDFMETDLE 105
>BUR1_ASPFU (Q4WTN5) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 580 Score = 73.2 bits (178), Expect = 3e-13 Identities = 41/93 (44%), Positives = 62/93 (66%), Gaps = 3/93 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +E L K+GEGT+G+VYKAR K G IVALKK + + +G P TALRE+ LL+MLS + Sbjct: 25 FEFLGKLGEGTFGEVYKARSKKDGSIVALKKILMHNEKDGFPITALREIKLLKMLSH-RN 83 Query: 356 VVRLLDLKQGQNK---EGQTILYLVFEYMDTDL 445 +++L ++ ++K + +Y+V YM+ DL Sbjct: 84 ILQLKEMAVERSKGDGRKKPSMYMVTPYMEHDL 116
>CDK9_XENTR (Q6GLD8) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 376 Score = 73.2 bits (178), Expect = 3e-13 Identities = 37/97 (38%), Positives = 63/97 (64%), Gaps = 7/97 (7%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE+L K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 356 VVRLLDL-------KQGQNKEGQTILYLVFEYMDTDL 445 VV L+++ Q + ++LVF++ + DL Sbjct: 78 VVNLIEICRTKISPTANQYNRCKGTIFLVFDFCEHDL 114
>CDK9B_XENLA (Q7ZX42) Cell division protein kinase 9-B (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-B) Length = 376 Score = 73.2 bits (178), Expect = 3e-13 Identities = 37/97 (38%), Positives = 63/97 (64%), Gaps = 7/97 (7%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE+L K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 356 VVRLLDL-------KQGQNKEGQTILYLVFEYMDTDL 445 VV L+++ Q + ++LVF++ + DL Sbjct: 78 VVHLIEICRNKISPTANQYNRCKGTIFLVFDFCEHDL 114
>CDK9A_XENLA (Q4V862) Cell division protein kinase 9-A (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-A) Length = 376 Score = 73.2 bits (178), Expect = 3e-13 Identities = 37/97 (38%), Positives = 63/97 (64%), Gaps = 7/97 (7%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE+L K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L + + Sbjct: 19 YERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE-N 77 Query: 356 VVRLLDL-------KQGQNKEGQTILYLVFEYMDTDL 445 VV L+++ Q + ++LVF++ + DL Sbjct: 78 VVNLIEICRTKVSPTANQYNRCKGTIFLVFDFCEHDL 114
>CDK4_HUMAN (P11802) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 72.8 bits (177), Expect = 4e-13 Identities = 41/101 (40%), Positives = 62/101 (61%), Gaps = 5/101 (4%) Frame = +2 Query: 164 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPE---DDEGVPPTALREVSLLR 334 A YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR Sbjct: 2 ATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLR 61 Query: 335 MLS--QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 L + P+VVRL+D+ + + + LVFE++D DL++ Sbjct: 62 RLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
>CDK4_RAT (P35426) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 72.4 bits (176), Expect = 5e-13 Identities = 40/97 (41%), Positives = 60/97 (61%), Gaps = 5/97 (5%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDE---GVPPTALREVSLLRMLS- 343 YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR L Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEA 65 Query: 344 -QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 + P+VVRL+D+ + + LVFE++D DL++ Sbjct: 66 FEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRT 102
>CDK4_MOUSE (P30285) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) (CRK3) Length = 303 Score = 72.4 bits (176), Expect = 5e-13 Identities = 40/97 (41%), Positives = 60/97 (61%), Gaps = 5/97 (5%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDE---GVPPTALREVSLLRMLS- 343 YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR L Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEA 65 Query: 344 -QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 + P+VVRL+D+ + + LVFE++D DL++ Sbjct: 66 FEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRT 102
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 71.6 bits (174), Expect = 9e-13 Identities = 41/93 (44%), Positives = 58/93 (62%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M YEK +++GEGTYG V KA + R VALKK + +D+G+P T++RE+++L L + Sbjct: 1 MTRYEKKQQLGEGTYGVVCKAWDTVCNRYVALKKIKQEREDDGIPVTSVREIAVLLEL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 P+VV L D+ LYLVFE+ D DL Sbjct: 60 HPNVVDLYDIYLEDK-----FLYLVFEFCDEDL 87
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 71.2 bits (173), Expect = 1e-12 Identities = 42/94 (44%), Positives = 63/94 (67%), Gaps = 3/94 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLSQ 346 YEKL+ +GEG + VYKAR+K T +IVA+KK +L E +G+ TALRE+ LL+ LS Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+++ LLD ++ + LVF++M+TDL+ Sbjct: 72 -PNIIGLLDAFGHKSN-----ISLVFDFMETDLE 99
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 71.2 bits (173), Expect = 1e-12 Identities = 42/94 (44%), Positives = 63/94 (67%), Gaps = 3/94 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLSQ 346 YEKL+ +GEG + VYKAR+K T +IVA+KK +L E +G+ TALRE+ LL+ LS Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+++ LLD ++ + LVF++M+TDL+ Sbjct: 72 -PNIIGLLDAFGHKSN-----ISLVFDFMETDLE 99
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 70.9 bits (172), Expect = 2e-12 Identities = 38/88 (43%), Positives = 60/88 (68%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YEK+ K+GEG+YG V+K R + TG+IVA+K+ EDD + ALRE+ +L+ L + Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQL-K 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEY 430 P++V LL++ + + + L+LVFEY Sbjct: 60 HPNLVSLLEVFRRKRR-----LHLVFEY 82
>CDC2H_CRIFA (Q01917) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 474 Score = 70.1 bits (170), Expect = 3e-12 Identities = 39/91 (42%), Positives = 55/91 (60%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y + K+GEGTYG VYK E TGR+VA K+ + DDEG+P A+RE+ LL+ L + + Sbjct: 7 YRHVVKLGEGTYGMVYKGTEIQTGRVVAFKRMVVTSDDEGIPGAAIREICLLKELRHN-N 65 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 VV L ++ K + ++FE D DLK Sbjct: 66 VVELFEVLFDPPK-----ITMIFELCDCDLK 91
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 70.1 bits (170), Expect = 3e-12 Identities = 40/93 (43%), Positives = 59/93 (63%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ +E L VGEG YG V K R K T IVA+KK + E++E V T LRE+ +LR L Q Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + +++LK+ + G+ LYLVFEY++ ++ Sbjct: 70 E----NIVELKEAFRRRGK--LYLVFEYVEKNM 96
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 69.3 bits (168), Expect = 5e-12 Identities = 40/90 (44%), Positives = 58/90 (64%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YE L VGEG+YG V K R K TGRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + ++V LL++ + + + YLVFE++D Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVD 84
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 69.3 bits (168), Expect = 5e-12 Identities = 40/90 (44%), Positives = 58/90 (64%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YE L VGEG+YG V K R K TGRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + ++V LL++ + + + YLVFE++D Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVD 84
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 69.3 bits (168), Expect = 5e-12 Identities = 40/90 (44%), Positives = 58/90 (64%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YE L VGEG+YG V K R K TGRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + ++V LL++ + + + YLVFE++D Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVD 84
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 68.6 bits (166), Expect = 8e-12 Identities = 41/93 (44%), Positives = 62/93 (66%), Gaps = 3/93 (3%) Frame = +2 Query: 179 EKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLSQD 349 EKL+ +GEG + VYKAR+K T +IVA+KK +L E +G+ TALRE+ LL+ LS Sbjct: 5 EKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH- 63 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 P+++ LLD ++ + LVF++M+TDL+ Sbjct: 64 PNIIGLLDAFGHKSN-----ISLVFDFMETDLE 91
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 67.8 bits (164), Expect = 1e-11 Identities = 39/90 (43%), Positives = 58/90 (64%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YE L VGEG+YG V K R K +GRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + ++V LL++ + + + YLVFE++D Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVD 84
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 67.8 bits (164), Expect = 1e-11 Identities = 39/90 (43%), Positives = 58/90 (64%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YE L VGEG+YG V K R K +GRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + ++V LL++ + + + YLVFE++D Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVD 84
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 67.8 bits (164), Expect = 1e-11 Identities = 39/90 (43%), Positives = 58/90 (64%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ YE L VGEG+YG V K R K +GRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + ++V LL++ + + + YLVFE++D Sbjct: 61 E-NLVNLLEVCKKKKR-----WYLVFEFVD 84
>CDK9_SCHPO (Q96WV9) Serine/threonine-protein kinase cdk9 (EC 2.7.11.1)| (Cyclin-dependent kinase cdk9) Length = 591 Score = 66.6 bits (161), Expect = 3e-11 Identities = 32/93 (34%), Positives = 59/93 (63%), Gaps = 3/93 (3%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y +EK+GEGT+G+VYK++ + G++ ALK+ + + EG P TA+RE+ +L+ + + + Sbjct: 36 YHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKHE-N 94 Query: 356 VVRLLDL---KQGQNKEGQTILYLVFEYMDTDL 445 ++ L D+ + + + +Y+V YMD DL Sbjct: 95 IIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDL 127
>CDK7_DICDI (P54685) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (MO15 homolog) Length = 362 Score = 65.5 bits (158), Expect = 7e-11 Identities = 42/98 (42%), Positives = 60/98 (61%), Gaps = 4/98 (4%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTR----LPEDDEGVPPTALREVSLLR 334 MD Y +GEGTYG V +A KATG+IVA+KK R + D+G+ +A+RE+ +L+ Sbjct: 1 MDKYNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQ 60 Query: 335 MLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 L D +VV LLD+ ++ +YLVFE M DL+ Sbjct: 61 ELKHD-NVVNLLDIFAHKSN-----VYLVFELMQWDLQ 92
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 65.1 bits (157), Expect = 9e-11 Identities = 35/97 (36%), Positives = 57/97 (58%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R + Y ++G+G YG V+KA ++ TG +VA+KK D+ RE++LL+ Sbjct: 8 RIVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEF 67 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLKS 451 P+++ LLD+ + +N +YLVFE+MDTDL + Sbjct: 68 GDHPNIISLLDVIRAENDRD---IYLVFEFMDTDLNA 101
>MK15_RAT (Q9Z2A6) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 547 Score = 65.1 bits (157), Expect = 9e-11 Identities = 35/87 (40%), Positives = 52/87 (59%) Frame = +2 Query: 191 KVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLL 370 ++G+G YG V+KA ++ TG +VA+KK D+ RE+ LLR P+++RLL Sbjct: 19 RLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIMLLREFGGHPNIIRLL 78 Query: 371 DLKQGQNKEGQTILYLVFEYMDTDLKS 451 D+ +N +YLVFE MDTDL + Sbjct: 79 DVIPAKNDRD---IYLVFESMDTDLNA 102
>CDK7_CARAU (P51953) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 344 Score = 63.9 bits (154), Expect = 2e-10 Identities = 35/70 (50%), Positives = 49/70 (70%), Gaps = 3/70 (4%) Frame = +2 Query: 173 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLS 343 LYEKL+ +GEG + VYKAR+K T IVA+KK ++ E +G+ TALRE+ LL+ LS Sbjct: 11 LYEKLDFLGEGQFATVYKARDKTTNTIVAIKKIKVGHRTEAKDGINRTALREIKLLQELS 70 Query: 344 QDPHVVRLLD 373 P+++ LLD Sbjct: 71 H-PNIIGLLD 79
>MK15_MOUSE (Q80Y86) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 549 Score = 63.2 bits (152), Expect = 3e-10 Identities = 34/87 (39%), Positives = 52/87 (59%) Frame = +2 Query: 191 KVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLL 370 ++G+G YG V+KA ++ TG +VA+KK D+ RE+ LL+ P+++RLL Sbjct: 19 RLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLL 78 Query: 371 DLKQGQNKEGQTILYLVFEYMDTDLKS 451 D+ +N +YLVFE MDTDL + Sbjct: 79 DVIPAKNDRD---IYLVFESMDTDLNA 102
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 62.0 bits (149), Expect = 7e-10 Identities = 35/91 (38%), Positives = 56/91 (61%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y K +KVGEGTY VY + +TGR +A+K+ + E +G+ +A+REV L+ + Q P+ Sbjct: 7 YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEM-QHPN 65 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 V+ L+D+ + L LV E++ TDL+ Sbjct: 66 VIELIDIFMAYDN-----LNLVLEFLPTDLE 91
>AL2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) Length = 384 Score = 61.6 bits (148), Expect = 1e-09 Identities = 41/94 (43%), Positives = 55/94 (58%) Frame = +2 Query: 164 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 343 A Y LEK+GEG+Y VYK + G++VALK + +EGVP TA+RE SLL+ L Sbjct: 48 AASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISM-NAEEGVPFTAIREASLLKGL- 105 Query: 344 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + ++V L D+ + L VFEYM TDL Sbjct: 106 KHANIVLLHDIIHTKE-----TLTFVFEYMHTDL 134
>CRK1_SCHPO (Q12126) Serine/threonine-protein kinase crk1 (EC 2.7.11.23)| (Mitotic catastrophe suppressor 6) Length = 335 Score = 61.2 bits (147), Expect = 1e-09 Identities = 34/91 (37%), Positives = 57/91 (62%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y K KVGEGTY V+ R+K T R VA+KK ++ + +G+ +ALRE+ LR S+ + Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRE-SRHDN 69 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 V+ L+D+ ++ L ++ E++D+DL+ Sbjct: 70 VIELVDVFSTKSN-----LNIILEFLDSDLE 95
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 60.5 bits (145), Expect = 2e-09 Identities = 37/93 (39%), Positives = 54/93 (58%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G+P ALRE+ L+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIED 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 +VV+L + G + L FE+M +DL Sbjct: 61 SQYVVQL----KAVFPHGAGFV-LAFEFMLSDL 88
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 60.5 bits (145), Expect = 2e-09 Identities = 37/93 (39%), Positives = 55/93 (59%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G+P ALRE+ L+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEMED 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + +VV+L + + G L FE+M +DL Sbjct: 61 NQYVVQLKAV--FPHSAG---FVLAFEFMLSDL 88
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 60.5 bits (145), Expect = 2e-09 Identities = 37/93 (39%), Positives = 54/93 (58%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G+P ALRE+ L+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIED 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 +VV+L + G + L FE+M +DL Sbjct: 61 SQYVVQL----KAVFPHGAGFV-LAFEFMLSDL 88
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 58.9 bits (141), Expect = 6e-09 Identities = 38/93 (40%), Positives = 54/93 (58%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G P ALRE+ L+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + +VV+ LK G + L FE+M +DL Sbjct: 61 NQYVVQ---LKAVFPHGGGFV--LAFEFMLSDL 88
>CCRK_MACMU (Q5EDC3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 243 Score = 58.9 bits (141), Expect = 6e-09 Identities = 38/93 (40%), Positives = 54/93 (58%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G P ALRE+ L+ + Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMGD 60 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + +VV+ LK G + L FE+M +DL Sbjct: 61 NQYVVQ---LKAVFPHGGGFV--LAFEFMLSDL 88
>CDKL3_MOUSE (Q8BLF2) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 595 Score = 58.2 bits (139), Expect = 1e-08 Identities = 34/90 (37%), Positives = 56/90 (62%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M++YE L KVGEG+YG V K + K TGRIVA+ K + ++ V A RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKDTGRIVAI-KIFYEKPEKSVNKIATREIKFLKQFRH 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + ++V L+++ + + K ++LVFE++D Sbjct: 60 E-NLVNLIEVFRQKKK-----IHLVFEFID 83
>CDKL3_RAT (Q9JM01) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIATRE) Length = 593 Score = 58.2 bits (139), Expect = 1e-08 Identities = 34/90 (37%), Positives = 56/90 (62%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M++YE L KVGEG+YG V K + K TGRIVA+ K + ++ V A RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKDTGRIVAI-KIFYEKPEKSVNKIATREIKFLKQFRH 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + ++V L+++ + + K ++LVFE++D Sbjct: 60 E-NLVNLIEVFRQKKK-----IHLVFEFID 83
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 57.8 bits (138), Expect = 1e-08 Identities = 33/90 (36%), Positives = 56/90 (62%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M++YE L KVGEG+YG V K + K TG+IVA+ K ++ V A+RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLKQFHH 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + ++V L+++ + + K ++LVFE++D Sbjct: 60 E-NLVNLIEVFRQKKK-----IHLVFEFID 83
>CDKL3_HUMAN (Q8IVW4) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIAMRE) Length = 592 Score = 57.8 bits (138), Expect = 1e-08 Identities = 33/90 (36%), Positives = 56/90 (62%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M++YE L KVGEG+YG V K + K TG+IVA+ K ++ V A+RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLKQFHH 59 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + ++V L+++ + + K ++LVFE++D Sbjct: 60 E-NLVNLIEVFRQKKK-----IHLVFEFID 83
>BUR1_CANAL (Q9Y7W4) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 746 Score = 55.8 bits (133), Expect = 5e-08 Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 8/98 (8%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE +EK+G+GT+G V KA+ K G +VA+K+ EG P TA+RE+++L+ L+ + Sbjct: 44 YEVIEKLGQGTFGVVQKAKSKKDGSLVAIKQLINHSAKEGFPITAMREITILKQLNH-KN 102 Query: 356 VVRLLDL-----KQGQNKEGQTI---LYLVFEYMDTDL 445 ++ + D+ K + T+ Y V YM +DL Sbjct: 103 ILTIQDMIFEEPKMSNRTDIITMRGSFYTVTPYMSSDL 140
>ERK1_CANAL (P28869) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) (MAPK 1) Length = 417 Score = 55.5 bits (132), Expect = 7e-08 Identities = 45/151 (29%), Positives = 73/151 (48%), Gaps = 11/151 (7%) Frame = +2 Query: 26 HQITRLARQPTREREREKARICAMATLQHQNQGAAAPMXXXXXX-----------LRAMD 172 HQ+ + +Q +++ + A+ A A Q Q Q AAA D Sbjct: 8 HQLQQQHQQQMLQQQAQ-AQAQAQAQAQQQQQAAAAAAAANAAATTSSSSPRQVSFNVSD 66 Query: 173 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 352 Y+ LE VGEG YG V A K + + VA+KK P + + LRE+ LL+ + + Sbjct: 67 HYQILEIVGEGAYGIVCSAIHKPSQQKVAIKKIE-PFERSMLCLRTLRELKLLKHFNHE- 124 Query: 353 HVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 +++ +L +++ N E +YL+ E M+TDL Sbjct: 125 NIISILAIQRPINYESFNEIYLIQELMETDL 155
>BUR1_DEBHA (Q6BV06) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 608 Score = 55.5 bits (132), Expect = 7e-08 Identities = 35/98 (35%), Positives = 59/98 (60%), Gaps = 8/98 (8%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE ++K+G+GT+G V KAR T +VALK+ EG P TA+RE+++L+ L+ + Sbjct: 39 YEIIQKLGQGTFGVVQKARNIKTKELVALKQLINHSAKEGFPITAMREITILKKLNH-KN 97 Query: 356 VVRLLDL--KQGQNKEGQTIL------YLVFEYMDTDL 445 +++++D+ ++ + Q IL Y V YM +DL Sbjct: 98 ILKIIDMIYEEPKISNPQDILHQRGCFYTVSPYMCSDL 135
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 55.1 bits (131), Expect = 9e-08 Identities = 34/104 (32%), Positives = 55/104 (52%) Frame = +2 Query: 134 PMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTAL 313 P + Y+ + VGEG YG V A K +G+ VA+KK P D L Sbjct: 9 PTGSRKISFNVSEQYDIQDVVGEGAYGVVCSAIHKPSGQKVAIKKI-TPFDHSMFCLRTL 67 Query: 314 REVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 RE+ LLR + + +++ +LD+++ +N E +YL+ E M+TD+ Sbjct: 68 REMKLLRYFNHE-NIISILDIQKPRNYESFNEVYLIQELMETDM 110
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 53.5 bits (127), Expect = 3e-07 Identities = 32/87 (36%), Positives = 53/87 (60%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 ++++ LEK+GEG+YG VYKA K TG+IVA+K+ + D + + ++E+S+++ Sbjct: 28 EVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEI----IKEISIMQQ-CDS 82 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEY 430 PHVV K + T L++V EY Sbjct: 83 PHVV-----KYYGSYFKNTDLWIVMEY 104
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 52.8 bits (125), Expect = 4e-07 Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 1/92 (1%) Frame = +2 Query: 173 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 352 +Y+ L+ VG G YG V A + TG VA+KK P E A RE+ LL+ + + Sbjct: 26 VYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHE- 84 Query: 353 HVVRLLDL-KQGQNKEGQTILYLVFEYMDTDL 445 +V+ LLD+ ++ + T YLV +M TDL Sbjct: 85 NVIGLLDVFTPDESLDDFTDFYLVMPFMGTDL 116
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 52.4 bits (124), Expect = 6e-07 Identities = 34/92 (36%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Frame = +2 Query: 173 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 352 +Y+ L+ VG G YG V A + TG VA+KK P E A RE+ LL+ + + Sbjct: 26 VYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHE- 84 Query: 353 HVVRLLDL-KQGQNKEGQTILYLVFEYMDTDL 445 +V+ LLD+ + + T YLV +M TDL Sbjct: 85 NVIGLLDVFTPDETLDDFTDFYLVMPFMGTDL 116
>ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) Length = 415 Score = 52.4 bits (124), Expect = 6e-07 Identities = 31/90 (34%), Positives = 49/90 (54%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y ++ +G G YG V A++ TG VA+KK D+ LRE+ LLR + + Sbjct: 31 YSIVKCIGHGAYGVVCSAKDNLTGEKVAIKKISKAFDNLKDTKRTLREIHLLRHFKHE-N 89 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 ++ + D+ + +KE +Y+V E MDTDL Sbjct: 90 LISIKDILKPNSKEQFEDVYIVSELMDTDL 119
>KSS1_YEAST (P14681) Mitogen-activated protein kinase KSS1 (EC 2.7.11.24) (MAP| kinase KSS1) (Kinase suppressor of SST2) Length = 368 Score = 51.6 bits (122), Expect = 1e-06 Identities = 30/91 (32%), Positives = 51/91 (56%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y+ ++ +GEG YG V A K +G VA+KK + P + +RE+ LLR + + Sbjct: 13 YKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQ-PFSKKLFVTRTIREIKLLRYFHEHEN 71 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 ++ +LD + + + +YLV E M+TDL+ Sbjct: 72 IISILDKVRPVSIDKLNAVYLVEELMETDLQ 102
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 51.6 bits (122), Expect = 1e-06 Identities = 31/94 (32%), Positives = 52/94 (55%), Gaps = 4/94 (4%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKT----RLPEDDEGVPPTALREVSLLRMLS 343 ++ +++G+G YG V+KA +K + VALKK R P D + REV L+ Sbjct: 13 FDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQ----RTFREVMFLQEFG 68 Query: 344 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + P+V++L ++ + N +YL FE+M+ DL Sbjct: 69 KHPNVIKLYNIFRADNDRD---IYLAFEFMEADL 99
>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC 2.7.11.24)| (MAP kinase 5) (AtMPK5) Length = 376 Score = 51.6 bits (122), Expect = 1e-06 Identities = 32/87 (36%), Positives = 47/87 (54%) Frame = +2 Query: 185 LEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVR 364 + +G G YG V A + T +A+KK D++ LRE+ LLR L + +VV Sbjct: 46 IRPIGRGAYGFVCAAVDSETHEEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHE-NVVV 104 Query: 365 LLDLKQGQNKEGQTILYLVFEYMDTDL 445 + D+ + KE +Y+VFE MDTDL Sbjct: 105 IKDIIRPPKKEDFVDVYIVFELMDTDL 131
>BUR1_CANGA (Q6FQ83) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 667 Score = 51.2 bits (121), Expect = 1e-06 Identities = 24/67 (35%), Positives = 48/67 (71%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y++ EK+G+GT+G+VYK T R VA+K+ + ++++ P TA RE+++L+ L+ + Sbjct: 60 YKEEEKLGQGTFGEVYKGLHLQTQRKVAMKRIIVNQENDLFPITAQREITILKRLNH-KN 118 Query: 356 VVRLLDL 376 +++LL++ Sbjct: 119 IIKLLEM 125
>BUR1_YEAST (P23293) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) (Suppressor of GPA1-Vall50 mutation protein 1) (Bypass UAS requirement protein 1) Length = 657 Score = 51.2 bits (121), Expect = 1e-06 Identities = 30/98 (30%), Positives = 53/98 (54%), Gaps = 8/98 (8%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y + EK+G+GT+G+VYK T R VA+KK + + + P TA RE+++L+ L+ + Sbjct: 60 YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNH-KN 118 Query: 356 VVRLL--------DLKQGQNKEGQTILYLVFEYMDTDL 445 +++L+ D+ + Y++ YM DL Sbjct: 119 IIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADL 156
>MK12_HUMAN (P53778) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 50.4 bits (119), Expect = 2e-06 Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = +2 Query: 173 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 352 +Y L+ VG G YG V A + TG VA+KK P E A RE+ LL+ + + Sbjct: 26 VYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHE- 84 Query: 353 HVVRLLDL-KQGQNKEGQTILYLVFEYMDTDL 445 +V+ LLD+ + + T YLV +M TDL Sbjct: 85 NVIGLLDVFTPDETLDDFTDFYLVMPFMGTDL 116
>SRK1_SCHPO (O94547) Serine/threonine-protein kinase srk1 (EC 2.7.11.1)| (Sty1-regulated kinase 1) Length = 580 Score = 50.4 bits (119), Expect = 2e-06 Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 11/141 (7%) Frame = +2 Query: 47 RQPTREREREKARICAMA-TLQHQNQGAAAPMXXXXXXLRAMDLYEKLEKVGEGTYGKVY 223 +QPT E+E +KA +A + ++ G P+ + ++ Y L+K+G+G + VY Sbjct: 86 KQPTNEKEYDKAIEALVAKAIVEEHSGQQFPVY------KGLEQYTLLQKMGDGAFSNVY 139 Query: 224 KAREKATGRIVALK---------KTRLPEDDEGVPP-TALREVSLLRMLSQDPHVVRLLD 373 KA TG VA+K R P +GV L+EV ++R + + P++++LL+ Sbjct: 140 KAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKEVQIMRRV-KHPNIIQLLE 198 Query: 374 LKQGQNKEGQTILYLVFEYMD 436 Q YLV E D Sbjct: 199 FIQTPE-----YYYLVLELAD 214
>BUR1_ASHGO (Q75D46) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 753 Score = 50.1 bits (118), Expect = 3e-06 Identities = 25/67 (37%), Positives = 48/67 (71%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y++ +K+G+GT+G+VY+ AT R VA+KK + +++ P TA RE+++L+ L+ + Sbjct: 56 YKEEKKLGQGTFGEVYRGVHLATQRQVAMKKILVKTENDLFPITAQREITILKRLNH-RN 114 Query: 356 VVRLLDL 376 VV+L+++ Sbjct: 115 VVQLIEM 121
>M4K1_HUMAN (Q92918) Mitogen-activated protein kinase kinase kinase kinase 1| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) Length = 833 Score = 49.7 bits (117), Expect = 4e-06 Identities = 23/55 (41%), Positives = 39/55 (70%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 334 D Y+ L+++G GTYG+V+KAR+K +G +VALK ++ DD+ T +E+ +L+ Sbjct: 15 DHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDD--VSTLQKEILILK 67
>MK12_BRARE (O42376) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Stress-activated protein kinase 3) Length = 363 Score = 49.7 bits (117), Expect = 4e-06 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D Y+ L++VG G YG V A ++ TG VA+KK P + A RE+ LL+ + D Sbjct: 23 DRYKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPFQSDLFAKRAYRELRLLKHMKHD 82 Query: 350 PHVVRLLDLKQGQ-NKEGQTILYLVFEYMDTDL 445 +V+ L+D+ + + YLV +M TDL Sbjct: 83 -NVIGLVDVFTADLSLDRFHDFYLVMPFMGTDL 114
>CDC2_PETHY (P43290) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) (Fragment) Length = 90 Score = 49.7 bits (117), Expect = 4e-06 Identities = 27/53 (50%), Positives = 37/53 (69%) Frame = +2 Query: 290 EGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDLK 448 EGVP TA+RE+SLL+ + Q ++VRL D+ + + LYLVFEY+D DLK Sbjct: 1 EGVPSTAIREISLLKEM-QHANIVRLQDVVHSEKR-----LYLVFEYLDLDLK 47
>MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (EC 2.7.11.24)| (MAP kinase 4) (AtMPK4) Length = 376 Score = 49.7 bits (117), Expect = 4e-06 Identities = 30/87 (34%), Positives = 46/87 (52%) Frame = +2 Query: 185 LEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVR 364 L +G G YG V A TG VA+KK D+ LRE+ LL+ + + +V+ Sbjct: 46 LRPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHE-NVIA 104 Query: 365 LLDLKQGQNKEGQTILYLVFEYMDTDL 445 + D+ + +E +Y+V+E MDTDL Sbjct: 105 VKDIIKPPQRENFNDVYIVYELMDTDL 131
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 49.7 bits (117), Expect = 4e-06 Identities = 28/86 (32%), Positives = 51/86 (59%), Gaps = 1/86 (1%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPE-DDEGVPPTALREVSLLRMLSQDP 352 YE E +G+GTYGKV +A E+ +GR+VA+K R + DE RE+ ++ L+ P Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNH-P 113 Query: 353 HVVRLLDLKQGQNKEGQTILYLVFEY 430 H++ + ++ + ++K + ++ EY Sbjct: 114 HIISIYEVFENKDK-----IVIIMEY 134
>WEE1_RAT (Q63802) Wee1-like protein kinase (EC 2.7.10.2)| Length = 646 Score = 49.3 bits (116), Expect = 5e-06 Identities = 25/63 (39%), Positives = 37/63 (58%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 + +LEK+G G +G V+K ++ G I A+K+++ P ALREV +L Q PH Sbjct: 298 FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPH 357 Query: 356 VVR 364 VVR Sbjct: 358 VVR 360
>WEE1_MOUSE (P47810) Wee1-like protein kinase (EC 2.7.10.2)| Length = 646 Score = 49.3 bits (116), Expect = 5e-06 Identities = 25/63 (39%), Positives = 37/63 (58%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 + +LEK+G G +G V+K ++ G I A+K+++ P ALREV +L Q PH Sbjct: 298 FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPH 357 Query: 356 VVR 364 VVR Sbjct: 358 VVR 360
>MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (EC 2.7.11.24)| (MAP kinase 2) (AtMPK2) Length = 376 Score = 49.3 bits (116), Expect = 5e-06 Identities = 31/90 (34%), Positives = 47/90 (52%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y ++ +G G YG V + + + VA+KK ++ LRE+ LLR L + + Sbjct: 32 YVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRHE-N 90 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 VV L D+ +K +YLV+E MDTDL Sbjct: 91 VVALKDVMMANHKRSFKDVYLVYELMDTDL 120
>MHK_ARATH (P43294) Serine/threonine-protein kinase MHK (EC 2.7.11.22)| Length = 443 Score = 49.3 bits (116), Expect = 5e-06 Identities = 35/92 (38%), Positives = 54/92 (58%), Gaps = 2/92 (2%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALK--KTRLPEDDEGVPPTALREVSLLRMLSQD 349 Y+ LE++G+GT G VYKA T +VA+K K + +E V LREV LR L+ Sbjct: 12 YKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECV---NLREVKALRKLNH- 67 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 PH+++L ++ + N+ L+ +FE MD +L Sbjct: 68 PHIIKLKEIVREHNE-----LFFIFECMDHNL 94
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 48.9 bits (115), Expect = 6e-06 Identities = 28/86 (32%), Positives = 51/86 (59%), Gaps = 1/86 (1%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPE-DDEGVPPTALREVSLLRMLSQDP 352 YE E +G+GTYGKV +A E+ +GR+VA+K R + DE RE+ ++ L+ P Sbjct: 56 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNH-P 114 Query: 353 HVVRLLDLKQGQNKEGQTILYLVFEY 430 H++ + ++ + ++K + ++ EY Sbjct: 115 HIISIYEVFENKDK-----IVIIMEY 135
>PIT1_SCHPO (O14132) Sporulation protein kinase pit1 (EC 2.7.11.1)| Length = 650 Score = 48.9 bits (115), Expect = 6e-06 Identities = 30/92 (32%), Positives = 50/92 (54%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 ++Y + KVG+GT+G VY A K + V K+ + + T LREV L LS++ Sbjct: 34 EVYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSEN 93 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 ++V + DL Q + L++V E++D +L Sbjct: 94 ENIVNIFDLYIDQFR----CLHIVMEFLDCNL 121
>MK14A_DROME (O62618) Mitogen-activated protein kinase 14A (EC 2.7.11.24) (MAP| kinase p38a) (p38 MAPK) (Dp38) (D-p38a) Length = 366 Score = 48.9 bits (115), Expect = 6e-06 Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 4/98 (4%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D+Y+ L+ VG G YG+V KA + T VA+KK P RE+ LL+ + + Sbjct: 23 DIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHE 82 Query: 350 PHVVRLLDLKQGQNKEGQ----TILYLVFEYMDTDLKS 451 +V+ LLD+ G +YLV MD DL + Sbjct: 83 -NVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNN 119
>CPK1_CRYNE (Q8NK05) Mitogen-activated protein kinase CPK1 (EC 2.7.11.24)| (Stress-activated protein kinase CPK1) Length = 366 Score = 48.9 bits (115), Expect = 6e-06 Identities = 34/90 (37%), Positives = 48/90 (53%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y+ E VGEG YG V +G VA+K+ P D LRE+ LLR + + Sbjct: 16 YKLEEIVGEGAYGLVVAGTHLPSGTQVAIKRIT-PFDHTMFCQRTLREIKLLRHFHHE-N 73 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 ++ +LDL Q ++ E +YLV E M+TDL Sbjct: 74 IISILDLIQPESYEVFNEVYLVQELMETDL 103
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 48.5 bits (114), Expect = 8e-06 Identities = 30/90 (33%), Positives = 47/90 (52%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y ++ +G G YG V + + T VA+KK ++ LRE+ LLR + + + Sbjct: 32 YVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLRHVRHE-N 90 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 V+ L D+ N+ +YLV+E MDTDL Sbjct: 91 VIALKDVMLPANRSSFKDVYLVYELMDTDL 120
>MYO3A_MOUSE (Q8K3H5) Myosin IIIA (EC 2.7.11.1)| Length = 1613 Score = 48.1 bits (113), Expect = 1e-05 Identities = 29/86 (33%), Positives = 47/86 (54%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D +E +E +G+GTYGKV+K K +G+ A+K + + + E ++LR LS Sbjct: 19 DTWEIIETIGKGTYGKVFKVLNKKSGQKAAVK---ILDPIHDIDEEIEAEYNILRTLSDH 75 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFE 427 P+VVR + ++K L+LV E Sbjct: 76 PNVVRFYGIYFKKDKINGDKLWLVLE 101
>FUS3_YEAST (P16892) Mitogen-activated protein kinase FUS3 (EC 2.7.11.24) (MAP| kinase FUS3) Length = 353 Score = 48.1 bits (113), Expect = 1e-05 Identities = 28/84 (33%), Positives = 46/84 (54%) Frame = +2 Query: 194 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 373 +GEG YG V A K TG IVA+KK P D LRE+ +L+ + +++ + + Sbjct: 19 LGEGAYGVVCSATHKPTGEIVAIKKIE-PFDKPLFALRTLREIKILKHFKHE-NIITIFN 76 Query: 374 LKQGQNKEGQTILYLVFEYMDTDL 445 +++ + E +Y++ E M TDL Sbjct: 77 IQRPDSFENFNEVYIIQELMQTDL 100
>NTF4_TOBAC (Q40532) Mitogen-activated protein kinase homolog NTF4 (EC| 2.7.11.24) (P45) Length = 393 Score = 47.8 bits (112), Expect = 1e-05 Identities = 28/84 (33%), Positives = 44/84 (52%) Frame = +2 Query: 194 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 373 +G+G YG V A T VA+KK D++ LRE+ LLR + + ++V + D Sbjct: 66 IGKGAYGIVCSALNSETNEHVAIKKIANAFDNKIDAKRTLREIKLLRHMDHE-NIVAIRD 124 Query: 374 LKQGQNKEGQTILYLVFEYMDTDL 445 + +E +Y+ +E MDTDL Sbjct: 125 IIPPPQREAFNDVYIAYELMDTDL 148
>MK07_MOUSE (Q9WVS8) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase) Length = 806 Score = 47.8 bits (112), Expect = 1e-05 Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D YE +E +G G YG V AR + TG+ VA+KK D LRE+ +L+ D Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112 Query: 350 PHVVRLLDLKQGQNKEGQ-TILYLVFEYMDTDL 445 +++ + D+ + G+ +Y+V + M++DL Sbjct: 113 -NIIAIKDILKPTVPYGEFRSVYVVLDLMESDL 144
>STK3_MOUSE (Q9JI10) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) Length = 497 Score = 47.8 bits (112), Expect = 1e-05 Identities = 28/87 (32%), Positives = 53/87 (60%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 ++++ LEK+GEG+YG V+KA K +G++VA+K+ + D + + ++E+S+++ Sbjct: 25 EVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEI----IKEISIMQQ-CDS 79 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEY 430 P+VV K + T L++V EY Sbjct: 80 PYVV-----KYYGSYFKNTDLWIVMEY 101
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 47.8 bits (112), Expect = 1e-05 Identities = 26/69 (37%), Positives = 41/69 (59%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y LE +GEG++G+VYK R K + ++VALK E RE+ ++R L + Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGL-R 59 Query: 347 DPHVVRLLD 373 P++V +LD Sbjct: 60 HPNIVHMLD 68
>STK36_HUMAN (Q9NRP7) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 47.8 bits (112), Expect = 1e-05 Identities = 26/69 (37%), Positives = 41/69 (59%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y LE +GEG++G+VYK R K + ++VALK E RE+ ++R L + Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGL-R 59 Query: 347 DPHVVRLLD 373 P++V +LD Sbjct: 60 HPNIVHMLD 68
>MMK1_MEDSA (Q07176) Mitogen-activated protein kinase homolog MMK1 (EC| 2.7.11.24) (MAP kinase MSK7) (MAP kinase ERK1) Length = 387 Score = 47.8 bits (112), Expect = 1e-05 Identities = 29/84 (34%), Positives = 44/84 (52%) Frame = +2 Query: 194 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 373 +G+G YG V A T VA+KK D++ LRE+ LLR + + +VV + D Sbjct: 61 IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHE-NVVAIRD 119 Query: 374 LKQGQNKEGQTILYLVFEYMDTDL 445 + +E +Y+ +E MDTDL Sbjct: 120 IVPPPQREVFNDVYIAYELMDTDL 143
>STK3_HUMAN (Q13188) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1) Length = 491 Score = 47.8 bits (112), Expect = 1e-05 Identities = 28/87 (32%), Positives = 53/87 (60%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 ++++ LEK+GEG+YG V+KA K +G++VA+K+ + D + + ++E+S+++ Sbjct: 25 EVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEI----IKEISIMQQ-CDS 79 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEY 430 P+VV K + T L++V EY Sbjct: 80 PYVV-----KYYGSYFKNTDLWIVMEY 101
>BUR1_KLULA (Q6CRA9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 645 Score = 47.8 bits (112), Expect = 1e-05 Identities = 23/77 (29%), Positives = 49/77 (63%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y + EK+G+GT+G+V+K T R VA+K+ + + + P TA RE+++L+ ++ + Sbjct: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH-KN 113 Query: 356 VVRLLDLKQGQNKEGQT 406 +V+L+++ ++ +T Sbjct: 114 IVKLIEIVYDESPTPKT 130
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 47.8 bits (112), Expect = 1e-05 Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D YE +E +G G YG V AR + TG+ VA+KK D LRE+ +L+ D Sbjct: 52 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 111 Query: 350 PHVVRLLDLKQGQNKEGQ-TILYLVFEYMDTDL 445 +++ + D+ + G+ +Y+V + M++DL Sbjct: 112 -NIIAIKDILRPTVPYGEFKSVYVVLDLMESDL 143
>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3 (EC| 2.7.11.24) (P43) Length = 372 Score = 47.4 bits (111), Expect = 2e-05 Identities = 30/90 (33%), Positives = 47/90 (52%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y ++ +G G YG V + + T VA+KK ++ LRE+ LLR L + + Sbjct: 32 YVPIKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTLRELKLLRHLRHE-N 90 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 V+ L D+ ++ +YLV+E MDTDL Sbjct: 91 VIALKDVMMPIHRRSFKDVYLVYELMDTDL 120
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 47.4 bits (111), Expect = 2e-05 Identities = 30/95 (31%), Positives = 53/95 (55%), Gaps = 2/95 (2%) Frame = +2 Query: 158 LRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 337 L +D ++ EK+G G + +VYK R + +G+++ LK +LP + LREV L+ Sbjct: 46 LARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRS----NTLREVQLMNR 101 Query: 338 LSQDPHVVRLLD--LKQGQNKEGQTILYLVFEYMD 436 L + P+++R + + QGQ L+ + EYM+ Sbjct: 102 L-RHPNILRFMGVCVHQGQ-------LHALTEYMN 128
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/94 (34%), Positives = 55/94 (58%), Gaps = 4/94 (4%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALK----KTRLPEDDEGVPPTALREVSLLRMLS 343 Y+ L+ +GEG++GKV A+ TG+ VALK KT D +G RE+S LR+L Sbjct: 53 YQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQG---RVEREISYLRLL- 108 Query: 344 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + PH+++L D+ + +++ + +V E+ +L Sbjct: 109 RHPHIIKLYDVIKSKDE-----IIMVIEFAGKEL 137
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 47.4 bits (111), Expect = 2e-05 Identities = 30/95 (31%), Positives = 53/95 (55%), Gaps = 2/95 (2%) Frame = +2 Query: 158 LRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 337 L +D ++ EK+G G + +VYK R + +G+++ LK +LP + LREV L+ Sbjct: 46 LARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRS----NTLREVQLMNR 101 Query: 338 LSQDPHVVRLLD--LKQGQNKEGQTILYLVFEYMD 436 L + P+++R + + QGQ L+ + EYM+ Sbjct: 102 L-RHPNILRFMGVCVHQGQ-------LHALTEYMN 128
>MPS1_YEAST (P54199) Serine/threonine-protein kinase MPS1 (EC 2.7.12.2)| (Regulatory cell proliferation kinase 1) Length = 764 Score = 47.4 bits (111), Expect = 2e-05 Identities = 30/90 (33%), Positives = 43/90 (47%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YEK+E +G G +VYK + R+ ALK+ D+ E+ LL L Sbjct: 440 YEKIELLGRGGSSRVYKVKGSGN-RVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKR 498 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 V++LLD + G +LYL+ E D DL Sbjct: 499 VIQLLDYEMGDG-----LLYLIMECGDHDL 523
>ATG1_NEUCR (Q7RX99) Serine/threonine-protein kinase atg-1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 932 Score = 47.0 bits (110), Expect = 2e-05 Identities = 26/83 (31%), Positives = 45/83 (54%) Frame = +2 Query: 188 EKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRL 367 +++G+G++ KVY R K TG +VA+K L ++ + E+ +L+ L + PH+V L Sbjct: 28 QEIGKGSFAKVYLGRHKVTGALVAVKSVELARLNKKLKENLYGEIQILKTL-RHPHIVAL 86 Query: 368 LDLKQGQNKEGQTILYLVFEYMD 436 D E T + L+ EY + Sbjct: 87 HDC-----VESSTHINLIMEYCE 104
>MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (PMEK1) Length = 384 Score = 47.0 bits (110), Expect = 2e-05 Identities = 30/90 (33%), Positives = 46/90 (51%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y ++ +G G YG V + + T VA+KK ++ LRE+ LLR L + + Sbjct: 32 YVPIKPIGRGAYGIVCSSVNRETNEKVAIKKINNAFENRIDALRTLRELKLLRHLRHE-N 90 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 V+ L D+ + +YLV+E MDTDL Sbjct: 91 VIALKDVMMPIQRRSFKDVYLVYELMDTDL 120
>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (MAP kinase 1) (AtMPK1) Length = 370 Score = 47.0 bits (110), Expect = 2e-05 Identities = 31/90 (34%), Positives = 46/90 (51%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 Y ++ +G G YG V + T VA+KK ++ LRE+ LLR L + + Sbjct: 32 YMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLRHLRHE-N 90 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 V+ L D+ +K +YLV+E MDTDL Sbjct: 91 VIALKDVMMPIHKMSFKDVYLVYELMDTDL 120
>STK36_MOUSE (Q69ZM6) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1268 Score = 47.0 bits (110), Expect = 2e-05 Identities = 26/69 (37%), Positives = 41/69 (59%) Frame = +2 Query: 167 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 346 M+ Y LE +GEG++G+VYK R+K + ++VALK E RE+ ++R L Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGL-W 59 Query: 347 DPHVVRLLD 373 P++V +LD Sbjct: 60 HPNIVHMLD 68
>MK13_RAT (Q9WTY9) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 46.6 bits (109), Expect = 3e-05 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = +2 Query: 194 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 373 VG G YG V A +K TG VA+KK P E A RE+ LL+ + + +V+ LLD Sbjct: 31 VGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHE-NVIGLLD 89 Query: 374 L-KQGQNKEGQTILYLVFEYMDTDLK 448 + + YLV +M TDL+ Sbjct: 90 VYTPATSVRNFQDFYLVMPFMQTDLQ 115
>MK13_MOUSE (Q9Z1B7) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 46.6 bits (109), Expect = 3e-05 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = +2 Query: 194 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 373 VG G YG V A +K TG VA+KK P E A RE+ LL+ + + +V+ LLD Sbjct: 31 VGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHE-NVIGLLD 89 Query: 374 L-KQGQNKEGQTILYLVFEYMDTDLK 448 + + YLV +M TDL+ Sbjct: 90 VFTPASSLRSFHDFYLVMPFMQTDLQ 115
>MAPK_PEA (Q06060) Mitogen-activated protein kinase homolog D5 (EC 2.7.11.24)| Length = 394 Score = 46.6 bits (109), Expect = 3e-05 Identities = 28/84 (33%), Positives = 44/84 (52%) Frame = +2 Query: 194 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 373 +G+G YG V A T VA+KK D++ LRE+ L+R + + +VV + D Sbjct: 68 IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLVRHMDHE-NVVAIRD 126 Query: 374 LKQGQNKEGQTILYLVFEYMDTDL 445 + +E +Y+ +E MDTDL Sbjct: 127 IVPPPQREVFNDVYIAYELMDTDL 150
>NEK2_HUMAN (P51955) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21) Length = 445 Score = 46.6 bits (109), Expect = 3e-05 Identities = 33/92 (35%), Positives = 48/92 (52%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 RA D YE L +G G+YG+ K R K+ G+I+ K+ E + EV+LLR L Sbjct: 4 RAED-YEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLREL 62 Query: 341 SQDPHVVRLLDLKQGQNKEGQTILYLVFEYMD 436 + P++VR D + T LY+V EY + Sbjct: 63 -KHPNIVRYYDRIIDRT---NTTLYIVMEYCE 90
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 46.6 bits (109), Expect = 3e-05 Identities = 31/94 (32%), Positives = 55/94 (58%), Gaps = 4/94 (4%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALK----KTRLPEDDEGVPPTALREVSLLRMLS 343 Y+ ++ +GEG++GKV A+ TG+ VALK KT D +G RE+S LR+L Sbjct: 52 YQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQG---RVEREISYLRLL- 107 Query: 344 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + PH+++L D+ + +++ + +V E+ +L Sbjct: 108 RHPHIIKLYDVIKSKDE-----IIMVIEFAGKEL 136
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 46.6 bits (109), Expect = 3e-05 Identities = 38/88 (43%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPE--DDEGVPPTALREVSLLRMLSQD 349 YE LEK+GEG KVYKA+ RIVA+K R PE DE RE LS Sbjct: 10 YEILEKIGEGGMAKVYKAKCHLLNRIVAIKILR-PEFAADENFVKKFKRESQAAASLSH- 67 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFEYM 433 P++V + D+ Q EG I Y+V EY+ Sbjct: 68 PNIVGIYDVGQ----EGD-IYYIVMEYV 90
>NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF6 (EC| 2.7.11.24) (P43) Length = 371 Score = 46.6 bits (109), Expect = 3e-05 Identities = 27/87 (31%), Positives = 47/87 (54%) Frame = +2 Query: 185 LEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVR 364 ++ VG G YG V A T VA+KK ++ LRE+ LL + + ++++ Sbjct: 41 IQPVGRGAYGMVCCATNSETKEEVAIKKIGNAFENRIDAKRTLREIKLLSHMDHE-NIIK 99 Query: 365 LLDLKQGQNKEGQTILYLVFEYMDTDL 445 + D+ + ++E +Y+V+E MDTDL Sbjct: 100 IKDIVRPPDREEFNDVYIVYELMDTDL 126
>MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK2 (EC| 2.7.11.24) Length = 371 Score = 46.6 bits (109), Expect = 3e-05 Identities = 31/87 (35%), Positives = 44/87 (50%) Frame = +2 Query: 185 LEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVR 364 + VG G YG V A T VA+KK D+ LRE+ LLR + + +V+ Sbjct: 40 IRSVGRGAYGIVCAAVNAETREEVAIKKIGNAFDNRIDAKRTLREIKLLRHMDHE-NVMS 98 Query: 365 LLDLKQGQNKEGQTILYLVFEYMDTDL 445 + D+ + KE +Y+V E MDTDL Sbjct: 99 IKDIIRPPQKENFNHVYIVSELMDTDL 125
>CDC22_PEA (P28567) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 151 Score = 46.2 bits (108), Expect = 4e-05 Identities = 28/75 (37%), Positives = 45/75 (60%), Gaps = 12/75 (16%) Frame = +2 Query: 257 ALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLDL---------KQGQ---NKEG 400 ALK+ R+ + EG P TA+RE+ +L+ L + +V++L ++ QG+ NK Sbjct: 1 ALKEIRMDNEREGFPITAIREIKILKKLHHE-NVIKLKEIVTSPGPEKDDQGRPDGNKYK 59 Query: 401 QTILYLVFEYMDTDL 445 + +Y+VFEYMD DL Sbjct: 60 RLAIYMVFEYMDHDL 74
>NEK2_MOUSE (O35942) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) Length = 443 Score = 46.2 bits (108), Expect = 4e-05 Identities = 30/87 (34%), Positives = 45/87 (51%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE L +G G+YG+ K R K+ G+I+ K+ E + EV+LLR L + P+ Sbjct: 8 YEVLHSIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEVEKQMLVSEVNLLREL-KHPN 66 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMD 436 +VR D + T LY+V EY + Sbjct: 67 IVRYYDRIIDRT---NTTLYIVMEYCE 90
>WEE1_HUMAN (P30291) Wee1-like protein kinase (EC 2.7.10.2) (WEE1hu)| Length = 646 Score = 46.2 bits (108), Expect = 4e-05 Identities = 24/63 (38%), Positives = 36/63 (57%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 + +LEK+G G +G V+K ++ G I A+K+++ P ALREV +L Q H Sbjct: 299 FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSH 358 Query: 356 VVR 364 VVR Sbjct: 359 VVR 361
>MK13_PANTR (Q9N272) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) Length = 365 Score = 46.2 bits (108), Expect = 4e-05 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = +2 Query: 194 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 373 VG G YG V A +K +G VA+KK P E A RE+ LL+ + Q +V+ LLD Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHM-QHENVIGLLD 89 Query: 374 L-KQGQNKEGQTILYLVFEYMDTDLK 448 + + YLV +M TDL+ Sbjct: 90 VFTPASSLRNFHDFYLVMXFMQTDLQ 115
>MK13_HUMAN (O15264) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 365 Score = 46.2 bits (108), Expect = 4e-05 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = +2 Query: 194 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 373 VG G YG V A +K +G VA+KK P E A RE+ LL+ + Q +V+ LLD Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHM-QHENVIGLLD 89 Query: 374 L-KQGQNKEGQTILYLVFEYMDTDLK 448 + + YLV +M TDL+ Sbjct: 90 VFTPASSLRNFYDFYLVMPFMQTDLQ 115
>SPK1_SCHPO (P27638) Mitogen-activated protein kinase spk1 (EC 2.7.11.24) (MAP| kinase spk1) (MAPK) Length = 372 Score = 45.8 bits (107), Expect = 5e-05 Identities = 30/90 (33%), Positives = 48/90 (53%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 YE + +G+G YG V A K +G VA+KK P + LRE+ LLR + + Sbjct: 39 YEMINLIGQGAYGVVCAALHKPSGLKVAVKKIH-PFNHPVFCLRTLREIKLLRHFRHE-N 96 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 ++ +LD+ + + +Y+V E M+TDL Sbjct: 97 IISILDILPPPSYQELEDVYIVQELMETDL 126
>MYO3A_HUMAN (Q8NEV4) Myosin IIIA (EC 2.7.11.1)| Length = 1616 Score = 45.8 bits (107), Expect = 5e-05 Identities = 28/86 (32%), Positives = 45/86 (52%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D +E E +G+GTYGKV+K K G+ A+K + + + E ++L+ LS Sbjct: 19 DTWEITETIGKGTYGKVFKVLNKKNGQKAAVK---ILDPIHDIDEEIEAEYNILKALSDH 75 Query: 350 PHVVRLLDLKQGQNKEGQTILYLVFE 427 P+VVR + ++K L+LV E Sbjct: 76 PNVVRFYGIYFKKDKVNGDKLWLVLE 101
>CDK8_DROME (Q9VT57) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (DmCdk8) Length = 454 Score = 45.8 bits (107), Expect = 5e-05 Identities = 33/87 (37%), Positives = 49/87 (56%), Gaps = 2/87 (2%) Frame = +2 Query: 191 KVGEGTYGKVYKAREKAT--GRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVR 364 KVG GTYG VYKA+ K T G+ ALK+ D G+ +A RE++LLR L +V+ Sbjct: 26 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQ-NVIT 80 Query: 365 LLDLKQGQNKEGQTILYLVFEYMDTDL 445 L+ + N ++L+ +Y + DL Sbjct: 81 LIRVFLSHNDRK---VFLLIDYAEHDL 104
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 45.8 bits (107), Expect = 5e-05 Identities = 30/95 (31%), Positives = 52/95 (54%), Gaps = 2/95 (2%) Frame = +2 Query: 158 LRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 337 L +D + EK+G G + +VYK R + +G+++ LK +LP + LREV L+ Sbjct: 51 LARVDDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSN----RGNTLREVQLMNR 106 Query: 338 LSQDPHVVRLLD--LKQGQNKEGQTILYLVFEYMD 436 L + P+++R + + QGQ L+ + EYM+ Sbjct: 107 L-RHPNILRFMGVCVHQGQ-------LHALTEYMN 133
>WEE1A_XENLA (P47817) Wee1-like protein kinase (EC 2.7.10.2)| Length = 555 Score = 45.4 bits (106), Expect = 7e-05 Identities = 31/99 (31%), Positives = 44/99 (44%), Gaps = 22/99 (22%) Frame = +2 Query: 182 KLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVV 361 ++EK+G G +G V+K ++ G A+K+++ P ALREV +L PHVV Sbjct: 212 EIEKIGAGEFGSVFKCVKRLDGCFYAIKRSKKPLAGSTDEQLALREVYAHAVLGHHPHVV 271 Query: 362 R----------------------LLDLKQGQNKEGQTIL 412 R L DL NKEGQ +L Sbjct: 272 RYYSAWAEDDHMIIQNEYCNGGSLQDLIVDNNKEGQFVL 310
>MPK6_ARATH (Q39026) Mitogen-activated protein kinase homolog 6 (EC 2.7.11.24)| (MAP kinase 6) (AtMPK6) Length = 395 Score = 45.4 bits (106), Expect = 7e-05 Identities = 27/84 (32%), Positives = 43/84 (51%) Frame = +2 Query: 194 VGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLD 373 +G+G YG V A T VA+KK D++ LRE+ LLR + + ++V + D Sbjct: 69 IGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHE-NIVAIRD 127 Query: 374 LKQGQNKEGQTILYLVFEYMDTDL 445 + + +Y+ +E MDTDL Sbjct: 128 IIPPPLRNAFNDVYIAYELMDTDL 151
>PMYT1_MOUSE (Q9ESG9) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 490 Score = 45.4 bits (106), Expect = 7e-05 Identities = 23/64 (35%), Positives = 35/64 (54%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +++L ++G G+YG+V+K R K GR+ A+K+ P L EV + Q PH Sbjct: 101 FQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRYMSPFRGPKDRTRKLAEVGGHEKVGQHPH 160 Query: 356 VVRL 367 VRL Sbjct: 161 CVRL 164
>PDK1L_BRARE (Q32PP3) Serine/threonine-protein kinase pdik1l (EC 2.7.11.1)| Length = 341 Score = 45.4 bits (106), Expect = 7e-05 Identities = 38/101 (37%), Positives = 56/101 (55%), Gaps = 10/101 (9%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL--PEDDEGVPPTALREV-SLLRMLSQ 346 YE +++VG G+YG VY+A + TG VA++K R PE+ E ALRE +L + SQ Sbjct: 8 YELIQEVGRGSYGVVYEAVVRQTGARVAVEKIRCHSPENVE----LALREFWALSSIQSQ 63 Query: 347 DPHVVRLLD-------LKQGQNKEGQTILYLVFEYMDTDLK 448 P+V+ L + L Q + + LYL E ++T LK Sbjct: 64 HPNVIHLEECVLQRDALAQRMSHGSSSSLYL--ELVETSLK 102
>M4K1_MOUSE (P70218) Mitogen-activated protein kinase kinase kinase kinase 1| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK) Length = 827 Score = 45.4 bits (106), Expect = 7e-05 Identities = 21/53 (39%), Positives = 37/53 (69%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 334 Y+ L+++G GTYG+V+KAR+K + +VALK ++ DD+ T +E+ +L+ Sbjct: 17 YDLLQRLGGGTYGEVFKARDKVSKDLVALKMVKMEPDDD--VATLQKEILMLK 67
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 45.4 bits (106), Expect = 7e-05 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 4/98 (4%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 + Y+ L+ VG+G YG+V KA + T VA+KK P RE+ LL+ + + Sbjct: 22 ETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHE 81 Query: 350 PHVVRLLDL----KQGQNKEGQTILYLVFEYMDTDLKS 451 +V+ LLD+ + + + +Y+V MD DL + Sbjct: 82 -NVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNN 118
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 45.1 bits (105), Expect = 9e-05 Identities = 31/94 (32%), Positives = 53/94 (56%), Gaps = 4/94 (4%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVAL----KKTRLPEDDEGVPPTALREVSLLRMLS 343 Y+ ++ +GEG++GKV A TG+ VAL KK D +G RE+S LR+L Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQG---RIEREISYLRLL- 110 Query: 344 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + PH+++L D+ + +++ + +V EY +L Sbjct: 111 RHPHIIKLYDVIKSKDE-----IIMVIEYAGNEL 139
>MINK1_MOUSE (Q9JM52) Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated| protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK) Length = 1308 Score = 45.1 bits (105), Expect = 9e-05 Identities = 22/62 (35%), Positives = 38/62 (61%) Frame = +2 Query: 173 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 352 ++E +E VG GTYG+VYK R TG++ A+K + ED+E +E+++L+ S Sbjct: 24 IFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEE---EEIKQEINMLKKYSHHR 80 Query: 353 HV 358 ++ Sbjct: 81 NI 82
>MINK1_HUMAN (Q8N4C8) Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated| protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK) Length = 1332 Score = 45.1 bits (105), Expect = 9e-05 Identities = 22/62 (35%), Positives = 38/62 (61%) Frame = +2 Query: 173 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDP 352 ++E +E VG GTYG+VYK R TG++ A+K + ED+E +E+++L+ S Sbjct: 24 IFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEE---EEIKQEINMLKKYSHHR 80 Query: 353 HV 358 ++ Sbjct: 81 NI 82
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/94 (32%), Positives = 53/94 (56%), Gaps = 4/94 (4%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVAL----KKTRLPEDDEGVPPTALREVSLLRMLS 343 Y+ ++ +GEG++GKV A TG+ VAL KK D +G RE+S LR+L Sbjct: 39 YQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQG---RIEREISYLRLL- 94 Query: 344 QDPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + PH+++L D+ + +++ + +V EY +L Sbjct: 95 RHPHIIKLYDVIKSKDE-----IIMVIEYAGNEL 123
>PMYT1_HUMAN (Q99640) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 499 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/96 (32%), Positives = 47/96 (48%) Frame = +2 Query: 176 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPH 355 +++L ++G G+YG+V+K R K GR+ A+K++ P L EV + Q P Sbjct: 110 FQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPC 169 Query: 356 VVRLLDLKQGQNKEGQTILYLVFEYMDTDLKSSSAA 463 VR L+Q + G ILYL E L+ A Sbjct: 170 CVR---LEQAWEEGG--ILYLQTELCGPSLQQHCEA 200
>CD2L6_HUMAN (Q9BWU1) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11) Length = 502 Score = 44.7 bits (104), Expect = 1e-04 Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 5/100 (5%) Frame = +2 Query: 161 RAMDLYEKLE-KVGEGTYGKVYKAREK--ATGRIVALKKTRLPEDDEGVPPTALREVSLL 331 R DL+E KVG GTYG VYKAR K + ALK+ + G+ +A RE++LL Sbjct: 15 RVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALL 70 Query: 332 RMLSQDPHVVRL--LDLKQGQNKEGQTILYLVFEYMDTDL 445 R L + P+V+ L + L K ++L+F+Y + DL Sbjct: 71 REL-KHPNVIALQKVFLSHSDRK-----VWLLFDYAEHDL 104
>M4K2_HUMAN (Q12851) Mitogen-activated protein kinase kinase kinase kinase 2| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-pro Length = 819 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/64 (39%), Positives = 40/64 (62%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D +E L++VG GTYG VYKAR+ T + A+K +L D+ + +E+++LR + Sbjct: 13 DRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDD--ISSLQQEITILRE-CRH 69 Query: 350 PHVV 361 P+VV Sbjct: 70 PNVV 73
>E2AK1_HUMAN (Q9BQI3) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 630 Score = 44.7 bits (104), Expect = 1e-04 Identities = 26/67 (38%), Positives = 40/67 (59%) Frame = +2 Query: 161 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 340 R ++ +E+L +G+G YG+VYK R K G+ A+KK + + V LREV +L L Sbjct: 162 RYLNEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGL 221 Query: 341 SQDPHVV 361 Q P++V Sbjct: 222 -QHPNIV 227
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 44.7 bits (104), Expect = 1e-04 Identities = 35/121 (28%), Positives = 57/121 (47%) Frame = +2 Query: 74 EKARICAMATLQHQNQGAAAPMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGRI 253 +K +I A ++ Q+ AA + D Y +++G G Y V +A+ K TG+ Sbjct: 167 KKPQISATSS-QNATTSAAIRKLNKTRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQ 225 Query: 254 VALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEYM 433 VA+K ++D+ RE + + M Q P++V LLD + Q YLV E + Sbjct: 226 VAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKI 285 Query: 434 D 436 D Sbjct: 286 D 286
>LIMK1_DROME (Q8IR79) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (dLIMK)| Length = 1257 Score = 44.7 bits (104), Expect = 1e-04 Identities = 27/82 (32%), Positives = 47/82 (57%) Frame = +2 Query: 188 EKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVVRL 367 EK+GEG +GKV+K + +G ++ LK+ L DE ++EV++LR+L HV++ Sbjct: 405 EKLGEGFFGKVFKVTHRQSGEVMVLKE--LHRADEEAQRNFIKEVAVLRLLDH-RHVLKF 461 Query: 368 LDLKQGQNKEGQTILYLVFEYM 433 + + K L++V EY+ Sbjct: 462 IGVLYKDKK-----LHMVTEYV 478
>M4K2_MOUSE (Q61161) Mitogen-activated protein kinase kinase kinase kinase 2| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein) Length = 821 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/64 (39%), Positives = 40/64 (62%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D +E L++VG GTYG VYKAR+ T + A+K +L D+ + +E+++LR + Sbjct: 14 DRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDD--ISSLQQEITILRE-CRH 70 Query: 350 PHVV 361 P+VV Sbjct: 71 PNVV 74
>CD2L6_MOUSE (Q8BWD8) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) Length = 501 Score = 44.7 bits (104), Expect = 1e-04 Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 5/100 (5%) Frame = +2 Query: 161 RAMDLYEKLE-KVGEGTYGKVYKAREK--ATGRIVALKKTRLPEDDEGVPPTALREVSLL 331 R DL+E KVG GTYG VYKAR K + ALK+ + G+ +A RE++LL Sbjct: 15 RVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALL 70 Query: 332 RMLSQDPHVVRL--LDLKQGQNKEGQTILYLVFEYMDTDL 445 R L + P+V+ L + L K ++L+F+Y + DL Sbjct: 71 REL-KHPNVIALQKVFLSHSDRK-----VWLLFDYAEHDL 104
>HIPK4_RAT (Q4V793) Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)| Length = 616 Score = 44.7 bits (104), Expect = 1e-04 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 1/93 (1%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQD 349 D Y+ +E +G+GT+G+V K ++TG +VA+K + + L+ + +R L D Sbjct: 9 DCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRSRIIKNELKLLRCVRGLDPD 68 Query: 350 -PHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 HV+R L+ K YLVFE ++ +L Sbjct: 69 EAHVIRFLEFFHDALK-----FYLVFELLEQNL 96
>HIPK4_MACFA (Q8WP28) Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)| Length = 616 Score = 44.7 bits (104), Expect = 1e-04 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS-Q 346 D Y+ +E +G+GT+G+V K ++TG +VA+K + + L+ + +R L + Sbjct: 9 DCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLHCMRGLDPE 68 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + HV+R L+ K YLVFE ++ +L Sbjct: 69 EAHVIRFLEFFHDALK-----FYLVFELLEQNL 96
>HIPK4_HUMAN (Q8NE63) Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)| Length = 616 Score = 44.7 bits (104), Expect = 1e-04 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = +2 Query: 170 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS-Q 346 D Y+ +E +G+GT+G+V K ++TG +VA+K + + L+ + +R L + Sbjct: 9 DCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLHCMRGLDPE 68 Query: 347 DPHVVRLLDLKQGQNKEGQTILYLVFEYMDTDL 445 + HV+R L+ K YLVFE ++ +L Sbjct: 69 EAHVIRFLEFFHDALK-----FYLVFELLEQNL 96
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 44.3 bits (103), Expect = 2e-04 Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 3/109 (2%) Frame = +2 Query: 113 QNQGAAAPMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALK---KTRLPE 283 +N+GA A +D +E +G+G +G VY AREK + IVALK K+++ Sbjct: 59 ENKGATALQGSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQI-- 116 Query: 284 DDEGVPPTALREVSLLRMLSQDPHVVRLLDLKQGQNKEGQTILYLVFEY 430 + EGV RE+ + L + P++++L + Q + +YL+ EY Sbjct: 117 EKEGVEHQLRREIEIQAHL-KHPNILQLYNYFYDQQR-----IYLILEY 159
>E2AK1_RABIT (P33279) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 626 Score = 44.3 bits (103), Expect = 2e-04 Identities = 30/97 (30%), Positives = 48/97 (49%) Frame = +2 Query: 71 REKARICAMATLQHQNQGAAAPMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGR 250 RE+ R A H + + + R ++ +E+L +G+G YG+VYK R K G+ Sbjct: 135 RERVRQDPCADNSHIQKIRSREVALEAQTSRYLNEFEELSILGKGGYGRVYKVRNKLDGQ 194 Query: 251 IVALKKTRLPEDDEGVPPTALREVSLLRMLSQDPHVV 361 A+KK + + LREV +L L Q P++V Sbjct: 195 YYAIKKILIKGATKTDCMKVLREVKVLAGL-QHPNIV 230 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.314 0.138 0.434 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,566,470 Number of Sequences: 219361 Number of extensions: 730722 Number of successful extensions: 4745 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4020 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4511 length of database: 80,573,946 effective HSP length: 102 effective length of database: 58,199,124 effective search space used: 3026354448 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits)
