ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bast47d06 |
|---|---|
| Clone Library Name | barley_pub |
>TOP3B_HUMAN (O95985) DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA| topoisomerase III beta-1) Length = 862 Score = 194 bits (494), Expect = 7e-50 Identities = 96/154 (62%), Positives = 117/154 (75%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 V + E T PDYL+E+ELI+LMEK+GIGTDASIPVHINNI +RNYV V +GRRL PT L Sbjct: 481 VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL 540 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKI 362 G L+ GY IDA+L LP IRS +E+Q+ LIA+GKAD+ QV+ H L+ F RK+ YFV I Sbjct: 541 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI 600 Query: 363 ENMDTLFEAQFSPLADSGRLLSKCGKCGRYMKYI 464 MD L E FSPLA +G+ LS+CGKC R+MKYI Sbjct: 601 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYI 634
>TOP3B_MOUSE (Q9Z321) DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA| topoisomerase III beta-1) Length = 862 Score = 194 bits (493), Expect = 9e-50 Identities = 96/154 (62%), Positives = 118/154 (76%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 V + E T+ PDYL+E+ELI+LMEK+GIGTDASIPVHINNI +RNYV V +GRRL PT L Sbjct: 481 VKMLEKQTSPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL 540 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKI 362 G L+ GY IDA+L LP IRS +E+Q+ LIA+GKAD+ QV+ H L+ F RK+ YFV I Sbjct: 541 GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYHQVLGHTLDIFKRKFHYFVDSI 600 Query: 363 ENMDTLFEAQFSPLADSGRLLSKCGKCGRYMKYI 464 MD L E FSPLA +G+ LS+CGKC R+MKYI Sbjct: 601 AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYI 634
>TOP3B_DROME (O96651) DNA topoisomerase 3-beta (EC 5.99.1.2) (DNA topoisomerase| III beta) Length = 875 Score = 191 bits (485), Expect = 8e-49 Identities = 90/154 (58%), Positives = 118/154 (76%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 V + E T PDYL+ESELI+LME++GIGTDASIPVHINNI +RNYV + GR+L+PT L Sbjct: 476 VRLIESQTGPPDYLTESELITLMEEHGIGTDASIPVHINNICQRNYVHIENGRKLMPTTL 535 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKI 362 G L+ GYQ ID +L LP +R+ +E+ +TLIA+G A+ V++H ++ F K+ YFVK I Sbjct: 536 GIVLVHGYQKIDPELVLPTMRTEVERMLTLIAQGSANFQDVLRHAIKIFKLKFMYFVKNI 595 Query: 363 ENMDTLFEAQFSPLADSGRLLSKCGKCGRYMKYI 464 ++MD LFE FSPLA+SG+ S+CGKC RYMKYI Sbjct: 596 DSMDALFEVSFSPLAESGKAHSRCGKCRRYMKYI 629
>TOP3A_DROME (Q9NG98) DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase| III alpha) Length = 1250 Score = 97.8 bits (242), Expect = 1e-20 Identities = 54/139 (38%), Positives = 80/139 (57%), Gaps = 2/139 (1%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 V ++EG+TTAP L+E++LI+LMEK+GIGTDA+ HIN I ER Y+ V LVP + Sbjct: 498 VSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYIGVLDKGFLVPGVI 557 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKI 362 G L GY ++ L P +R+ E + LI +G+ D V+ + ++ + Y KI Sbjct: 558 GMGLYEGYDAMELALAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQQITDKI 617 Query: 363 ENMDTLFEAQF--SPLADS 413 MD A+ +P A+S Sbjct: 618 TAMDAKISARINETPAANS 636
>TOP3A_MOUSE (O70157) DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase| III alpha) Length = 1003 Score = 94.7 bits (234), Expect = 1e-19 Identities = 45/124 (36%), Positives = 78/124 (62%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 V++ +G T+ P L+E++LI+LMEK+GIGTDA+ HI I R YV + + +R +P L Sbjct: 505 VEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTSDKRFLPGHL 564 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKI 362 G L+ GY + ++ PD+R+ +E + LI +GK D QV++ ++++ + + V K Sbjct: 565 GMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKFQVLRQQVQKYKQVFIEAVAKA 624 Query: 363 ENMD 374 + +D Sbjct: 625 KKLD 628
>TOP3A_HUMAN (Q13472) DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase| III alpha) Length = 1001 Score = 90.9 bits (224), Expect = 1e-18 Identities = 51/161 (31%), Positives = 87/161 (54%), Gaps = 10/161 (6%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 V++ +G T+ P L+E++LI+LMEK+GIGTDA+ HI I R YV + +R +P L Sbjct: 505 VEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHL 564 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKI 362 G L+ GY + ++ PD+R+ +E + LI GK D V++ ++++ + + V K Sbjct: 565 GMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKKDKFVVLRQQVQKYKQVFIEAVAKA 624 Query: 363 ENMDTLFEAQF---SPLADSGRL-------LSKCGKCGRYM 455 + +D F + LA + + KC +C + M Sbjct: 625 KKLDEALAQYFGNGTELAQQEDIYPAMPEPIRKCPQCNKDM 665
>TOP3_CAEEL (O61660) DNA topoisomerase 3 (EC 5.99.1.2) (DNA topoisomerase III)| Length = 759 Score = 80.9 bits (198), Expect = 2e-15 Identities = 47/128 (36%), Positives = 74/128 (57%), Gaps = 1/128 (0%) Frame = +3 Query: 9 IYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGT 188 I +G T APD+L+E++LISLM+K GIGTDA+ HI I R Y+ V +L+P+ LG Sbjct: 480 IGDGKTQAPDFLTEADLISLMDKYGIGTDATHAEHIEKIKTREYIGVRPDGKLIPSFLGL 539 Query: 189 TLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKY-SYFVKKIE 365 L+ GY + + PD+R+ +E + I G+ Q VL++ + KY + FV+ Sbjct: 540 ALVDGYDDMGFAMSKPDLRANLEIGLKEICDGRRQK----QEVLDEQIGKYRAIFVESER 595 Query: 366 NMDTLFEA 389 + L ++ Sbjct: 596 KIGVLSQS 603
>TOP3_YEAST (P13099) DNA topoisomerase 3 (EC 5.99.1.2) (DNA topoisomerase III)| Length = 656 Score = 77.8 bits (190), Expect = 1e-14 Identities = 47/122 (38%), Positives = 70/122 (57%), Gaps = 5/122 (4%) Frame = +3 Query: 18 GSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYV---QVNTGRRLVPTALGT 188 G+T P ++ESELI LM+ NGIGTDA+I HI+ I RNYV +V L PT LG Sbjct: 523 GTTAPPKPMTESELILLMDTNGIGTDATIAEHIDKIQVRNYVRSEKVGKETYLQPTTLGV 582 Query: 189 TLIRGYQCI--DADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKI 362 +L+ G++ I + P R +EQ + I +G A V++ ++E++ RKY + Sbjct: 583 SLVHGFEAIGLEDSFAKPFQRREMEQDLKKICEGHASKTDVVKDIVEKY-RKYWHKTNAC 641 Query: 363 EN 368 +N Sbjct: 642 KN 643
>TOP3_SCHPO (O60126) DNA topoisomerase 3 (EC 5.99.1.2) (DNA topoisomerase III)| Length = 622 Score = 76.3 bits (186), Expect = 4e-14 Identities = 43/116 (37%), Positives = 67/116 (57%), Gaps = 7/116 (6%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGR-----RL 167 +D+ + ST++P Y++E ELI+LM+ NGIGTDA++ HI + ER YV R Sbjct: 477 LDMMDSSTSSPSYITEPELIALMDANGIGTDATMAEHIEKVQEREYVIKRKKRGQGVTEF 536 Query: 168 VPTALGTTLIRGYQCIDAD--LCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQF 329 VP++LG L +GY I + L P +R +E Q+ I G+ + ++ +L QF Sbjct: 537 VPSSLGVALAKGYDEIGLEWSLTKPFLRKEMEVQLKNIENGQLNRNVLVHMILTQF 592
>TOP1_FERIS (O34204) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 699 Score = 54.3 bits (129), Expect = 2e-07 Identities = 38/147 (25%), Positives = 68/147 (46%) Frame = +3 Query: 15 EGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTL 194 E TT PD +E+ L+ +E GIG ++ I + +R YV V + L+PT LG + Sbjct: 476 EAQTTPPDRYTEASLVKTLEMEGIGRPSTYATIIQTLLDRGYV-VKKRKTLIPTILGFVV 534 Query: 195 IRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMD 374 + D+ + +E+++ + GK D +V++ L++F + + +D Sbjct: 535 NHYLEQRFPDIVDKGFTAEMEKELDEVENGKKDWKEVVKSFLKEFNKDLERAKNEFFAID 594 Query: 375 TLFEAQFSPLADSGRLLSKCGKCGRYM 455 F+ + SG K GK G Y+ Sbjct: 595 --FDTDITCEDCSGNYKLKVGKYGLYL 619
>TOP1_BACHD (Q9KA23) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 690 Score = 50.1 bits (118), Expect = 3e-06 Identities = 36/153 (23%), Positives = 72/153 (47%), Gaps = 5/153 (3%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P +E+ L+ ME+ GIG ++ ++ I +R YV ++ RR VPT LG ++ Sbjct: 454 TQPPPRYTEARLVKTMEELGIGRPSTYAPTLDTIQKRGYVALDE-RRFVPTELGEIVLEL 512 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLF 383 ++ + + +E + I +GK +++I + F + ++++ ++ Sbjct: 513 MTEFFPEILDVEFTAKMEDDLDSIEEGKQQWIKIIDDFYKGFEERLKVAEEEMKEVEIKD 572 Query: 384 EAQFSPLADSGRLLSKCG-----KCGRYMKYIS 467 E +G + KCG K GRY K+++ Sbjct: 573 E-------PTGEMCEKCGHEMVYKMGRYGKFMA 598
>TOP1_ARCFU (O28469) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 663 Score = 47.0 bits (110), Expect = 2e-05 Identities = 38/147 (25%), Positives = 66/147 (44%), Gaps = 3/147 (2%) Frame = +3 Query: 15 EGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTL 194 E T P S S LI +MEK +GT ++ I + R Y+ N R P+ ++ Sbjct: 453 EKETKPPGRYSASSLIKMMEKLNLGTKSTRHEIIQKLVSRRYIHGNPFR---PSETAFSV 509 Query: 195 IRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVI---QHVLEQFMRKYSYFVKKIE 365 I + + LPD+ + +E ++ LIA+GK +V+ + +L Q +R Y +K+ Sbjct: 510 INVLKETAETITLPDMTAKLENEMDLIAEGKKREPEVVDESREMLLQILRAIDY--RKLS 567 Query: 366 NMDTLFEAQFSPLADSGRLLSKCGKCG 446 +++ KC +CG Sbjct: 568 K-------DLREGVKKDKIVGKCPECG 587
>TOP1_CAMJE (Q9PLZ2) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 700 Score = 46.6 bits (109), Expect = 3e-05 Identities = 35/144 (24%), Positives = 68/144 (47%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SE+ L+ +E GIG ++ I+ ++ R+YV ++ ++L+P+ + + Sbjct: 449 TEPPSRYSEAGLVKKLESLGIGRPSTYAPTISILTSRDYVTIDK-KQLIPSDVAFNVTEV 507 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLF 383 + +D+ S +E + IA+ KAD + ++ FMRK KI + T+ Sbjct: 508 LEKNFSDIVDSKFTSNLENTLDEIAEDKADWQETLKEFYYPFMRKIEEGKTKIASQKTVT 567 Query: 384 EAQFSPLADSGRLLSKCGKCGRYM 455 + S G L + G+ G ++ Sbjct: 568 KLGESCPDCGGELAIRKGRFGEFV 591
>TOP1_LACLA (Q9CG80) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 710 Score = 45.4 bits (106), Expect = 7e-05 Identities = 38/151 (25%), Positives = 71/151 (47%), Gaps = 5/151 (3%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SE+ LI +E+NG+G ++ + I +R YV++ + +R PT LG + + Sbjct: 470 TQPPARYSEATLIKTLEENGVGRPSTYAPTLETIQKRYYVRL-SAKRFEPTELGEIVNKL 528 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLF 383 ++ + + +E+ + + +GK ++V+ +QF Y F K++EN + Sbjct: 529 IVEFFPNIVNTEFTAEMEKDLDEVEEGKRQWIEVV----DQF---YKPFAKELENAEEGM 581 Query: 384 EAQFSPLADSGRLLSKCG-----KCGRYMKY 461 E +G CG K GR+ K+ Sbjct: 582 EKIQIKDEPAGFDCDVCGSPMVIKLGRFGKF 612
>RGYR_PYRAE (Q8ZXT5) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1228 Score = 45.1 bits (105), Expect = 9e-05 Identities = 30/101 (29%), Positives = 55/101 (54%), Gaps = 2/101 (1%) Frame = +3 Query: 42 LSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRR--LVPTALGTTLIRGYQCI 215 LS++++++LM + GIG ++ + +++R YV V TGR ++PT G + R + Sbjct: 1122 LSQADVLALMRQRGIGRPSTYAHILQVLAKRYYVYV-TGRTKLMIPTKRGREIFRFLKEA 1180 Query: 216 DADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRK 338 L D IEQ + I GKA + +VI + ++F ++ Sbjct: 1181 FGKLVSEDRTRLIEQYMDAIEVGKARYEEVIAELYDEFRKE 1221
>TOP1_BACSU (P39814) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 691 Score = 44.7 bits (104), Expect = 1e-04 Identities = 34/150 (22%), Positives = 70/150 (46%), Gaps = 2/150 (1%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P +E+ L+ +E+ GIG ++ ++ I R YV ++ +R VPT LG ++ Sbjct: 454 TQPPPRYTEARLVKTLEERGIGRPSTYAPTLDTIQRRGYVALD-NKRFVPTELGQIVLDL 512 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLF 383 ++ + + +E+ + + +G + +++I + F ++ VKK E+ Sbjct: 513 IMEFFPEIINVEFTAKMERDLDHVEEGNTEWVKIIDNFYTDFEKR----VKKAESEMKEV 568 Query: 384 EAQFSPLADSGRLLSK--CGKCGRYMKYIS 467 E + + L S K GRY K+++ Sbjct: 569 EIEPEYAGEDCELCSSPMVYKMGRYGKFLA 598
>RGYR_ARCFU (O29238) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1054 Score = 43.9 bits (102), Expect = 2e-04 Identities = 25/89 (28%), Positives = 48/89 (53%) Frame = +3 Query: 45 SESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRGYQCIDAD 224 ++SE+I +M++ GIG ++ ++ + RNYV G R++PT LG + R A Sbjct: 957 TQSEIIQMMKERGIGRPSTYATIVDRLFMRNYVVEKYG-RMIPTKLGIDVFRFLVRRYAK 1015 Query: 225 LCLPDIRSFIEQQITLIAKGKADHLQVIQ 311 D +E ++ I +G+ D+L+ ++ Sbjct: 1016 FVSEDRTRDLESRMDAIERGELDYLKALE 1044
>TOP1_PSEAE (Q9HZJ5) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 868 Score = 43.5 bits (101), Expect = 3e-04 Identities = 40/145 (27%), Positives = 68/145 (46%), Gaps = 1/145 (0%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SE+ L+ +EK GIG ++ I+ I ER YV + RR +G + Sbjct: 476 TKPPARYSEASLVKELEKRGIGRPSTYAAIISTIQERGYVTTH-NRRFYAEKMGDIVTDR 534 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLF 383 A+L + +E+ + +A+G+ D +H+L++F Y F KK+E + Sbjct: 535 LNESFANLMDYGFTAGMEEHLDDVAQGERDW----KHLLDEF---YGDFKKKLEVAEV-- 585 Query: 384 EAQFSPLADSGRLLS-KCGKCGRYM 455 ++ A+ L + C +CGR M Sbjct: 586 -SEKGMRANQPTLTNIPCRECGRPM 609
>TOP1_AQUAE (O66893) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 540 Score = 42.7 bits (99), Expect = 5e-04 Identities = 28/108 (25%), Positives = 50/108 (46%) Frame = +3 Query: 15 EGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTL 194 E T P +E LI +EK GIG ++ + + ER YV+V + LVPT + + Sbjct: 428 ERKTQPPPRYTEGTLIKTLEKLGIGRPSTYATIVKTLKERGYVEVKK-KALVPTEIAFQV 486 Query: 195 IRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRK 338 + L + +E+++ L+ +GK + V+ +E+ K Sbjct: 487 VEFLMERFPTLMDYKFTAQMEEKLDLVEEGKLNWKSVVYEFMEKIFGK 534
>TOP1_BORBU (O51768) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 848 Score = 42.4 bits (98), Expect = 6e-04 Identities = 29/98 (29%), Positives = 47/98 (47%) Frame = +3 Query: 15 EGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTL 194 E T AP +E+ L+ MEK GIG ++ I+ + ER Y L+PT G + Sbjct: 472 EHETKAPFRYTEASLVQKMEKEGIGRPSTYSTIISTLLEREYA-FKLNNTLMPTIKGAAV 530 Query: 195 IRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVI 308 I + L + S +E+++ IA GK D ++ + Sbjct: 531 INLLEKYFPVLIELNFTSNMEEKLDKIAIGKLDKIKYL 568
>RGYR_PYRFU (P95479) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1214 Score = 41.2 bits (95), Expect = 0.001 Identities = 22/98 (22%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Frame = +3 Query: 45 SESELISLMEKNGIGTDASIPVHINNISERNYV-QVNTGRRLVPTALGTTLIRGYQCIDA 221 ++ ++I+LM++ GIG ++ + + +R YV + + ++LVPT G + Sbjct: 1113 TQGDVIALMKERGIGRPSTYAKIVQTLLQRGYVIETKSKKKLVPTEKGIKVYHYLVSKYK 1172 Query: 222 DLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMR 335 DL + +E+ + ++ + KA++ +V+ + E+ +R Sbjct: 1173 DLVSEERTRQLEKLMDMVEEAKANYQEVLNELYEEILR 1210
>TOP1_SYNY3 (P73810) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 898 Score = 41.2 bits (95), Expect = 0.001 Identities = 28/103 (27%), Positives = 47/103 (45%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 +D T P +E+ L+ +E G+G ++ I I +R YVQ+ + + L PT Sbjct: 472 IDTVGHETQPPARYTEASLVKTLESEGVGRPSTYASIIGTIIDRGYVQMRS-KALTPTFT 530 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQ 311 ++ + DL S +EQ++ IA GK L +Q Sbjct: 531 AFAVVSLLESHFPDLVDTGFTSRMEQKLDEIAIGKTQWLPYLQ 573
>RGYR_PYRAB (Q9UZ86) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1214 Score = 40.8 bits (94), Expect = 0.002 Identities = 26/98 (26%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Frame = +3 Query: 45 SESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGR-RLVPTALGTTLIRGYQCIDA 221 ++ ++I+LM++ GIG ++ + + +R YV GR +LVPT G + + Sbjct: 1113 TQGDVIALMKERGIGRPSTYAKIVQTLLQRGYVIETKGRKKLVPTEKGIKVYQYLVSKYK 1172 Query: 222 DLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMR 335 DL + +E+ + I + KAD+ +V++ + E+ R Sbjct: 1173 DLVSEERTRQLEKIMDEIEEAKADYQEVLRELHEEIKR 1210
>TOP1P_XYLFA (Q9PHK2) DNA topoisomerase I, plasmid (EC 5.99.1.2) (Omega-protein)| (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 660 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%) Frame = +3 Query: 9 IYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALG- 185 + E T P + +++ L+ +E GIG A+ ++NI R YV+ + L PT G Sbjct: 442 LLEKKTKPPSHYTQATLVKKLESEGIGRPATYAAIMDNIVSRGYVKTEK-KYLFPTETGE 500 Query: 186 ---TTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYS 344 +L+ ++ +D IE+ + IA+G++ + VI V +Q + S Sbjct: 501 LIVDSLVGKFEFLDLGFTRE-----IEESLDRIAQGESGYKAVIAKVHDQLNMELS 551
>TOP1_ECOLI (P06612) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 865 Score = 40.4 bits (93), Expect = 0.002 Identities = 27/105 (25%), Positives = 48/105 (45%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SE+ L+ +EK GIG ++ I+ I +R YV+V RR +G + Sbjct: 471 TKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVE-NRRFYAEKMGEIVTDR 529 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRK 338 + +L D + +E + +A +A+ V+ H F ++ Sbjct: 530 LEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQ 574
>TOP1_METJA (Q59046) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 761 Score = 40.4 bits (93), Expect = 0.002 Identities = 33/148 (22%), Positives = 64/148 (43%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 + I T P + + +I +EK G+GT A+ I+ + +R YV ++ G L T L Sbjct: 459 ITITRKETQPPKRYTVASIIKELEKRGLGTKATRAEIIDKLIKRGYV-IDDG-SLKVTDL 516 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKI 362 G ++I + ++ + +E+++ I K V+ ++ + F KK Sbjct: 517 GISVIETLKRFCPEIIDEKMTRDLEEKLEKIQFRKIKKDDVLDEAEKRLRKILEEFKKKE 576 Query: 363 ENMDTLFEAQFSPLADSGRLLSKCGKCG 446 E++ +++ KC KCG Sbjct: 577 EDIGIYLIKNLDATNKKAKIVGKCPKCG 604
>RGYR_PYRHO (O58530) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] [Contains: Pho r-Gyr intein] Length = 1624 Score = 40.4 bits (93), Expect = 0.002 Identities = 24/98 (24%), Positives = 51/98 (52%), Gaps = 1/98 (1%) Frame = +3 Query: 45 SESELISLMEKNGIGTDASIPVHINNISERNYVQVNTG-RRLVPTALGTTLIRGYQCIDA 221 ++ ++I+LM++ GIG ++ + + +R YV G ++LVPT G + + Sbjct: 1524 TQGDVIALMKERGIGRPSTYAKIVQTLLQRGYVIETKGKKKLVPTEKGIKVYQYLITKYK 1583 Query: 222 DLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMR 335 DL + +E+ + ++ + KAD+ V+ + E+ R Sbjct: 1584 DLVSEERTRQLEKIMDMVEEAKADYQDVLNELYEEIKR 1621
>TOP1_VIBCH (Q9KRB2) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 876 Score = 40.0 bits (92), Expect = 0.003 Identities = 28/104 (26%), Positives = 49/104 (47%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P +E+ L+ +EK GIG ++ I+ I +R YV+V+ RR +G + Sbjct: 478 TKPPARYTEAALVKELEKRGIGRPSTYASIISTIQDRGYVKVDQ-RRFFAEKMGEIVTDR 536 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMR 335 DL D + +E+++ IA+G+ + V+ F R Sbjct: 537 LDENFDDLMNYDFTARMEEKLDQIAEGEVNWTAVLDEFFADFSR 580
>TOP1_HAEIN (P43012) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 868 Score = 40.0 bits (92), Expect = 0.003 Identities = 37/144 (25%), Positives = 61/144 (42%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P +E+ L+ +EK GIG ++ I+ I ER YV+ RR +G + Sbjct: 477 TKPPARFTEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTE-NRRFYAEKMGEIVTDR 535 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLF 383 +L D + +E + IA G + + L QF + +S + K E + Sbjct: 536 LNESFGELMNYDFTANMEDTLDKIASGSVNW----KTELNQFFKDFSSQLSKAELDELEG 591 Query: 384 EAQFSPLADSGRLLSKCGKCGRYM 455 + + L ++ KC CGR M Sbjct: 592 GMRPNSLVETD---IKCPTCGRNM 612
>TOP1_PYRFU (O73954) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) [Contains: Endonuclease PI-PfuI (EC 3.1.-.-) (Pfu topA intein)] Length = 1060 Score = 39.7 bits (91), Expect = 0.004 Identities = 34/146 (23%), Positives = 64/146 (43%), Gaps = 5/146 (3%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P S + +I ME G+GT A+ + + +R Y++ ++ P LG +I Sbjct: 844 TKPPARYSPAAVIKKMEDLGLGTKATRAQILETLYQRGYIEGKKSIKVTP--LGMKVIET 901 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKK-----IEN 368 + ++ ++ E+++ LI +GK +VI+ + + F KK +E Sbjct: 902 LEKYVPEIISVELTREFEKKMELIMEGKLTKEEVIEEAKIRLTKILEEFKKKELEIGLEL 961 Query: 369 MDTLFEAQFSPLADSGRLLSKCGKCG 446 + + PL ++ KC KCG Sbjct: 962 AKIVVGEEKPPL-----IVGKCPKCG 982
>TOP1_PYRHO (O58356) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 686 Score = 39.7 bits (91), Expect = 0.004 Identities = 33/147 (22%), Positives = 65/147 (44%), Gaps = 6/147 (4%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P S + +I ME G+GT A+ + + +R Y++ ++ P LG +I Sbjct: 471 TKPPARYSPAAVIKKMEDLGLGTKATRAQILETLYQRGYIEGKKSIKVTP--LGMKVIET 528 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMD--- 374 + ++ ++ E+++ LI +G+ +VI+ E+ + F K+ + Sbjct: 529 LEKYVPEIISVELTREFEKKMELIMEGRLTKEEVIEEAKERLTKILEEFKKRELEIGIEL 588 Query: 375 ---TLFEAQFSPLADSGRLLSKCGKCG 446 + E + PL ++ KC KCG Sbjct: 589 AKIVVGEDEVKPL-----VVGKCPKCG 610
>TOP1_HELPY (P55991) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 736 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/144 (22%), Positives = 65/144 (45%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SE+ LI ++E GIG ++ I+ + R+Y++V +++ +I Sbjct: 448 TEPPARYSEASLIKVLESLGIGRPSTYAPTISLLQNRDYIKVEK-KQISALESAFKVIEI 506 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLF 383 + ++ + +E+++ IA+ KAD+ QV++ FM K K I + Sbjct: 507 LEKHFEEIVDSKFSASLEEELDNIAQNKADYQQVLKDFYYPFMDKIEAGKKNIISQKVHE 566 Query: 384 EAQFSPLADSGRLLSKCGKCGRYM 455 + S G L+ K + G ++ Sbjct: 567 KTGQSCPKCGGELVKKNSRYGEFI 590
>TOP1_HELPJ (Q9ZMV7) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 736 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/144 (22%), Positives = 65/144 (45%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SE+ LI ++E GIG ++ I+ + R+Y++V +++ +I Sbjct: 448 TEPPARYSEASLIKVLESLGIGRPSTYAPTISLLQNRDYIKVEK-KQISALESAFKVIEI 506 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLF 383 + ++ + +E+++ IA+ KAD+ QV++ FM K K I + Sbjct: 507 LEKHFEEIVDSKFSASLEEELDNIAQNKADYQQVLKDFYYPFMDKIEAGKKNIISQKVHE 566 Query: 384 EAQFSPLADSGRLLSKCGKCGRYM 455 + S G L+ K + G ++ Sbjct: 567 KTGQSCPKCGGELVKKNSRYGEFI 590
>TOP1_METTH (O27661) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 718 Score = 38.1 bits (87), Expect = 0.011 Identities = 32/144 (22%), Positives = 65/144 (45%) Frame = +3 Query: 15 EGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTL 194 E T P +E+ LI +E+ G+GT ++ I + +R Y++ G+++ + LG + Sbjct: 466 ERETKPPARYNEASLIRELERRGLGTKSTRADIIAKLYDRKYIE---GKKIRVSPLGENI 522 Query: 195 IRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMD 374 I + ++ E+++ I +GK +VI + + S EN+ Sbjct: 523 IDTLTRYCEKIISEELTRQFERELEDIMRGKISKDRVIDEAITEVR---SILSDIEENLR 579 Query: 375 TLFEAQFSPLADSGRLLSKCGKCG 446 + + + DS R++ +C CG Sbjct: 580 DIGKELYRAYQDS-RVVGECPACG 602
>TOP1_RICCN (Q92IH1) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 776 Score = 38.1 bits (87), Expect = 0.011 Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 18/162 (11%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALG---TTL 194 T P SE+ L+ +E+ GIG ++ ++ + +R YV + +R +P LG T Sbjct: 463 TEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEK-KRFIPEELGRLVTVF 521 Query: 195 IRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQV-----------IQHVLEQFMRKY 341 + G+ + D + +E ++ IA GK + I+ V EQ + + Sbjct: 522 LVGFFKKYVEY---DFTAGLENELDAIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEI 578 Query: 342 SYFVKKIENMDTLF----EAQFSPLADSGRLLSKCGKCGRYM 455 +V+K + LF E++ P ++G L K GK G ++ Sbjct: 579 ISYVQKALDYH-LFGENKESKICPSCNTGELSLKLGKFGAFL 619
>TOP1_BUCAP (Q8K9P7) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 853 Score = 38.1 bits (87), Expect = 0.011 Identities = 28/107 (26%), Positives = 49/107 (45%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SES L+ +EK GIG ++ I I E+ Y+++ + +G LI Sbjct: 461 TKPPPRFSESSLVRELEKKGIGRPSTYATIITKIKEKGYLKIKK-NKFYAAKIGEILITR 519 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYS 344 + +DL D + +E+ + + +D L +H+L F +S Sbjct: 520 LKKNFSDLVDYDFTARMEKNLDQV----SDKLINWKHLLNSFFDNFS 562
>TOP1_SALTY (P0A2I1) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 865 Score = 37.7 bits (86), Expect = 0.015 Identities = 26/105 (24%), Positives = 48/105 (45%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SE+ L+ +EK GIG ++ I+ I +R YV+V RR +G + Sbjct: 471 TKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVE-NRRFYAEKMGEIVTDR 529 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRK 338 + +L D + +E + +A +A+ V+ + F ++ Sbjct: 530 LEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQ 574
>TOP1_SALTI (P0A2I2) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 865 Score = 37.7 bits (86), Expect = 0.015 Identities = 26/105 (24%), Positives = 48/105 (45%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SE+ L+ +EK GIG ++ I+ I +R YV+V RR +G + Sbjct: 471 TKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVE-NRRFYAEKMGEIVTDR 529 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRK 338 + +L D + +E + +A +A+ V+ + F ++ Sbjct: 530 LEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDNFFSDFTQQ 574
>TOP1_PYRAB (Q9UYS8) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 685 Score = 37.7 bits (86), Expect = 0.015 Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 7/148 (4%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P S + +I ME GIGT A+ + + +R Y++ ++ P LG +I Sbjct: 471 TKPPARYSPAAVIKKMEDLGIGTKATRAQILETLYQRGYIEGKKSIKVTP--LGMKVIET 528 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQH-------VLEQFMRKYSYFVKKI 362 + ++ ++ E+++ LI +GK +VI+ +LE+F ++ ++ Sbjct: 529 LEKYVPEIISVELTREFERKMDLIMQGKLTKEEVIEEAKVKLTKILEEFKKRELEIGLEL 588 Query: 363 ENMDTLFEAQFSPLADSGRLLSKCGKCG 446 + + + + + ++ KC KCG Sbjct: 589 ARI-VVGDVKDEIKEEKPIVVGKCPKCG 615
>TOP1_PASMU (Q9CN30) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 868 Score = 37.7 bits (86), Expect = 0.015 Identities = 40/144 (27%), Positives = 63/144 (43%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SE+ L+ +EK GIG ++ I+ I ER YV+V RR +G + Sbjct: 477 TKPPARFSEAALVKELEKRGIGRPSTYAAIISTIQERGYVRVE-NRRFYAEKMGEIVTDR 535 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLF 383 L D + +E + IA G+ + + L QF + +S + + E +D L Sbjct: 536 LNQSFTALMNYDFTANMENILDQIANGEKNW----KTELNQFFKDFSQQLSQAE-LDEL- 589 Query: 384 EAQFSPLADSGRLLSKCGKCGRYM 455 E P + ++ C CGR M Sbjct: 590 EGGMKPNSLVPTDIN-CPTCGRKM 612
>RGYR_METJA (Q58907) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] [Contains: Mja r-Gyr intein] Length = 1613 Score = 37.4 bits (85), Expect = 0.019 Identities = 24/100 (24%), Positives = 53/100 (53%), Gaps = 5/100 (5%) Frame = +3 Query: 48 ESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGR-RLVPTALG----TTLIRGYQC 212 E E++ LM++ GIG ++ I + +R YV + + +L+PT LG LI Y Sbjct: 1515 EGEVVKLMKERGIGRPSTYAQIIKKLLDRGYVVKSKDKNKLIPTKLGIEVYNYLINNYPH 1574 Query: 213 IDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFM 332 + ++ ++ +++ I G+ D+++V++ + E+ + Sbjct: 1575 LISEERTRELEEIMDK----IENGEVDYIEVLKALHEEIL 1610
>RGYR2_SULTO (Q975P6) Reverse gyrase 2 [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1233 Score = 36.2 bits (82), Expect = 0.043 Identities = 20/92 (21%), Positives = 50/92 (54%), Gaps = 1/92 (1%) Frame = +3 Query: 45 SESELISLMEKNGIGTDASIPVHINNISERNYV-QVNTGRRLVPTALGTTLIRGYQCIDA 221 +++EL++ M++ IG ++ I+ I +R YV + ++L+PT LG + + + Sbjct: 1134 TQAELVAEMKRKEIGRPSTYATIISTILKRGYVIESKKTKKLIPTQLGKEVNKYLNQKFS 1193 Query: 222 DLCLPDIRSFIEQQITLIAKGKADHLQVIQHV 317 + + Q + ++ +GK D++Q+++ + Sbjct: 1194 SFVSEERTRNLLQLMDMVEQGKQDYIQILKDI 1225
>TOP1_AERPE (Q9YB01) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 673 Score = 36.2 bits (82), Expect = 0.043 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 7/127 (5%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 VD+ + P L ++ L+ ME IGT+ + I + +R Y++ R+ T L Sbjct: 458 VDVRVEWSQTPVRLDKASLLRWMESVNIGTEGTRARIIETLYKRGYLE--GSRKSEVTPL 515 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQV-------IQHVLEQFMRKY 341 G + Q + +L PD+ E I I G+ +V I +LE F+ + Sbjct: 516 GEAVAVIIQTLFPELSKPDLTRRFESMIEDIRSGRRTRQEVIDMSKKTISKLLESFLDRL 575 Query: 342 SYFVKKI 362 V++I Sbjct: 576 DTAVREI 582
>TOP1_RICPR (Q9ZDK2) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 776 Score = 36.2 bits (82), Expect = 0.043 Identities = 37/165 (22%), Positives = 71/165 (43%), Gaps = 21/165 (12%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALG---TTL 194 T P SE+ L+ +E+ GIG ++ ++ + +R YV + +R +P LG T Sbjct: 463 TEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEK-KRFIPEELGRLVTVF 521 Query: 195 IRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMD 374 + G+ + D + +E ++ IA GK + + L F R +++ ++ + Sbjct: 522 LVGFFKKYVEY---DFTAGLENELDEIAAGKLEW----KTALNNFWRGFNHNIESVNEQK 574 Query: 375 T--------------LF----EAQFSPLADSGRLLSKCGKCGRYM 455 LF E++ P +G+L K GK G ++ Sbjct: 575 ITEIINYLQKALDYHLFGEDKESKVCPSCKTGQLSLKLGKFGAFL 619
>TOP1_SYNP7 (P34185) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 883 Score = 35.4 bits (80), Expect = 0.073 Identities = 33/128 (25%), Positives = 53/128 (41%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P +E+ L+ ++E GIG ++ I I +R Y Q+ L PT + Sbjct: 479 TQPPARYTEASLVKMLENEGIGRPSTYASIIGTIVDRGYAQL-VSNTLTPTFTAFAVTAL 537 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLF 383 + DL + +EQ + I+ G+ D L L QF R + +E L Sbjct: 538 LEQHFPDLVDTSFSARMEQSLDDISNGEVDWLP----YLSQFYRG----DRGLEEQVKLR 589 Query: 384 EAQFSPLA 407 E++ P A Sbjct: 590 ESEIDPAA 597
>TOP1_MYCGA (Q9JN65) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 719 Score = 35.4 bits (80), Expect = 0.073 Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 4/124 (3%) Frame = +3 Query: 15 EGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTL 194 E T P +++ LI +E GIG ++ ++ + +RNY ++ GR T LG L Sbjct: 493 EHQTKPPARFTQATLIEALETEGIGRPSTYSTILDIVLKRNYAELVNGRYYKTTDLGQKL 552 Query: 195 IRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFM----RKYSYFVKKI 362 + + +E + IA+G + + +Q F + VKK+ Sbjct: 553 AFELDKNFPTIINKEFTKNMETTLDEIAQGTVNDVSYLQAFWNDFSEVLNEAKTNIVKKV 612 Query: 363 ENMD 374 E ++ Sbjct: 613 EYIE 616
>TOP1_BUCAI (P57371) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 861 Score = 35.4 bits (80), Expect = 0.073 Identities = 24/107 (22%), Positives = 52/107 (48%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P SE+ L+ +EK GIG ++ + I +R YV++ + +G L Sbjct: 468 TKPPPRFSEASLVRELEKKGIGRPSTYSAITSKIQDRGYVKIKK-NKFYAEKMGEILTIR 526 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYS 344 + ++L + + +E+++ +A+ K +++L+ F +K+S Sbjct: 527 LKKSFSNLIDYNFTAHMEKKLDQVAENKV----TWRYLLDDFFKKFS 569
>RGYR1_AQUAE (O67037) Reverse gyrase 1 [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1146 Score = 35.4 bits (80), Expect = 0.073 Identities = 28/109 (25%), Positives = 56/109 (51%), Gaps = 5/109 (4%) Frame = +3 Query: 45 SESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRGYQCIDA- 221 ++ L+ M++ GIG ++ ++ + ER YV G L+PT LG + Y+ + + Sbjct: 1043 TQGSLVEEMKRRGIGRPSTYATIVSKLLERGYVIERHG-FLIPTKLGKQV---YEFLKSR 1098 Query: 222 DLCLP----DIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVK 356 + +P + +E+ + + +GK D+LQ VL++ +K + F K Sbjct: 1099 EKIMPFVSEEFTRKLEELMDKVEEGKEDYLQ----VLDELYKKVNEFEK 1143
>RGYR1_SULSO (Q97ZZ8) Reverse gyrase 1 [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1242 Score = 34.7 bits (78), Expect = 0.12 Identities = 22/96 (22%), Positives = 53/96 (55%), Gaps = 2/96 (2%) Frame = +3 Query: 45 SESELISLMEKNGIGTDASIPVHINNISERNY-VQVNTGRRLVPTALGTTLIRGYQCIDA 221 +E ELIS M+ IG ++ V I+ + +R Y ++ ++++PT LG ++ Y + Sbjct: 1143 TEGELISEMKSKQIGRPSTYAVIISTLKKRRYIIESKNLKKIIPTKLGMA-VKEYLMENY 1201 Query: 222 DLCLPDIRSF-IEQQITLIAKGKADHLQVIQHVLEQ 326 + + R+ + +++ + +GK D+L +++ + + Sbjct: 1202 KQIVSEKRTVKLLEKMNEVEEGKVDYLVLLKELYNE 1237
>RGYR2_AQUAE (O67226) Reverse gyrase 2 [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1159 Score = 34.7 bits (78), Expect = 0.12 Identities = 21/91 (23%), Positives = 46/91 (50%) Frame = +3 Query: 45 SESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRGYQCIDAD 224 ++ LI M++ G+G ++ + + ER+YV G L+PT LG + + Sbjct: 1055 TQGTLIQEMKRRGLGRPSTYAQIVQTLLERHYVVEEKG-FLIPTDLGREVYEYLTKHFPE 1113 Query: 225 LCLPDIRSFIEQQITLIAKGKADHLQVIQHV 317 ++ +E+ + I +G+ D+++V++ V Sbjct: 1114 WTSEELTRKLEEAMDKIERGELDYMEVLKEV 1144
>RGYR_PYRKO (Q6F598) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] [Contains: Pko r-Gyr intein] Length = 1711 Score = 34.3 bits (77), Expect = 0.16 Identities = 23/101 (22%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Frame = +3 Query: 45 SESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGR-RLVPTALGTTLIRGYQCIDA 221 ++ ++I+LM++ IG ++ + + R YV GR +L+PT G + Sbjct: 1610 TQGDIIALMKERKIGRPSTYAKIVETLMRRGYVVETKGRKKLLPTEKGIKVYHYLVSKYR 1669 Query: 222 DLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYS 344 DL + +E+ + I +G D+++V+ + + R S Sbjct: 1670 DLVSEERTRELEEIMDRIEEGIEDYIKVLGELYSEIQRYVS 1710
>TOP1_THEMA (P46799) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 633 Score = 33.9 bits (76), Expect = 0.21 Identities = 26/109 (23%), Positives = 49/109 (44%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 V I E T +E L+ ME+ GIG ++ I + R Y++ G L PT + Sbjct: 432 VKIEEQETKPKPRYTEGSLVKEMERLGIGRPSTYASTIKLLLNRGYIKKIRG-YLYPTIV 490 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQF 329 G+ ++ + +D+ + +E+ + + +GK V++ E F Sbjct: 491 GSVVMDYLEKKYSDVVSVSFTAEMEKDLDEVEQGKKTDKIVLREFYESF 539
>TOP1_XYLFT (Q87AQ6) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 815 Score = 33.5 bits (75), Expect = 0.28 Identities = 21/96 (21%), Positives = 45/96 (46%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P +E+ L+ +E+ GIG ++ I + R YV + GR PT +G + + Sbjct: 469 TQPPPRYTEAALVKALEEYGIGRPSTYASIIQTLLFRKYVDME-GRSFRPTDIGRAVSKF 527 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQ 311 D + +E ++ I++G+ + + +++ Sbjct: 528 LSSHFTQYVDYDFTAHLEDELDAISRGEEEWIPLMK 563
>TOP1_XYLFA (Q9PEV8) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 815 Score = 32.3 bits (72), Expect = 0.62 Identities = 21/96 (21%), Positives = 45/96 (46%) Frame = +3 Query: 24 TTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRG 203 T P +E+ L+ +E+ GIG ++ I + R YV + GR PT +G + + Sbjct: 469 TQPPPRYTEAALVKALEEYGIGRPSTYASIIQTLLFRKYVDME-GRSFRPTDIGRAVSKF 527 Query: 204 YQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQ 311 D + +E ++ I++G+ + + +++ Sbjct: 528 LASHFTRYVDYDFTAHLEDELDAISRGEEEWIPLMK 563
>TOP1_MYCLE (O69548) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 947 Score = 32.0 bits (71), Expect = 0.80 Identities = 17/52 (32%), Positives = 28/52 (53%) Frame = +3 Query: 21 STTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPT 176 +T P +E+ L+ +E+ GIG ++ I + +R YVQ G LVP+ Sbjct: 508 ATNPPARYTEASLVKALEELGIGRPSTYSSIIKTVQDRGYVQ-KKGSALVPS 558
>RGYR2_SULSO (Q97ZF5) Reverse gyrase 2 [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1166 Score = 32.0 bits (71), Expect = 0.80 Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 2/110 (1%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRR--LVPT 176 V+I +GS+ LS S++ISLM+ GIG ++ I N+ + Y+ V++ R+ L+ T Sbjct: 1046 VNITKGSSE--QLLSYSDVISLMKSKGIGRPSTYAKTIENLMKHGYI-VSSKRKSYLIAT 1102 Query: 177 ALGTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQ 326 G ++ + DL S + ++ IA K + V+ + + Sbjct: 1103 NRGISVYQFLSSKFYDLVSESTTSRLMTKLDDIALSKLNASTVLLEIFSE 1152
>TOP1_MYCGE (P47368) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 709 Score = 31.6 bits (70), Expect = 1.0 Identities = 28/122 (22%), Positives = 51/122 (41%) Frame = +3 Query: 3 VDIYEGSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTAL 182 + + E T P +++ LI +EK+ IG ++ + ER Y + R T L Sbjct: 486 ISVNEHKTNPPPRYTQASLIEELEKSNIGRPSTYNTMASVNLERGYANL-VNRFFYITEL 544 Query: 183 GTTLIRGYQCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKI 362 G + ++ + +E+ + IA+ K ++ Q L+QF + VK Sbjct: 545 GEKVNNELSKHFGNVINKEFTKKMEKSLDEIAENKVNY----QEFLKQFWTNFKSDVKLA 600 Query: 363 EN 368 EN Sbjct: 601 EN 602
>TOP1_BACAN (P40114) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 870 Score = 31.2 bits (69), Expect = 1.4 Identities = 24/112 (21%), Positives = 49/112 (43%) Frame = +3 Query: 27 TAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRGY 206 TA + + L LM+ IGT A+ I + E+N++ + G +++ T +G I + Sbjct: 477 TAGRKIDDEHLKELMKGKRIGTVATEAAFIPVLHEKNFIDIEKG-KIITTPIGRAFIEQF 535 Query: 207 QCIDADLCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQFMRKYSYFVKKI 362 ++ + T +G ++ + E F+ + + FV+KI Sbjct: 536 ----------PVQQIKDPLYTAEMEGMIHRIEKNEMSYENFIAQTNAFVQKI 577
>POLG_PEMVC (Q01500) Genome polyprotein [Contains: P1 proteinase (N-terminal| protein); Helper component proteinase (EC 3.4.22.45) (HC-pro); Protein P3; 6 kDa protein 1 (6K1); Cytoplasmic inclusion protein (EC 3.6.1.-) (CI); 6 kDa protein 2 (6K2); Viral ge Length = 3068 Score = 30.4 bits (67), Expect = 2.3 Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 6/51 (11%) Frame = +3 Query: 315 VLEQFMRKYSYFVKKIENMDTLFEAQFSPLADSGRLLS------KCGKCGR 449 VLE++M Y + K+ +LF A+ DSG +L+ K G+C R Sbjct: 206 VLEEWMNDYVLNLSKVSTWGSLFHAESLKRGDSGLILNARALRGKFGRCSR 256
>TOP1_MYCTU (P0A620) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 934 Score = 30.4 bits (67), Expect = 2.3 Identities = 17/52 (32%), Positives = 27/52 (51%) Frame = +3 Query: 21 STTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPT 176 +T P +E+ L+ +E+ GIG ++ I I +R YV G LVP+ Sbjct: 510 ATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVH-KKGSALVPS 560
>TOP1_MYCBO (P0A621) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 934 Score = 30.4 bits (67), Expect = 2.3 Identities = 17/52 (32%), Positives = 27/52 (51%) Frame = +3 Query: 21 STTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPT 176 +T P +E+ L+ +E+ GIG ++ I I +R YV G LVP+ Sbjct: 510 ATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVH-KKGSALVPS 560
>PENK_CAVPO (P47969) Proenkephalin A precursor [Contains: Synenkephalin;| Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe] Length = 268 Score = 30.4 bits (67), Expect = 2.3 Identities = 19/64 (29%), Positives = 33/64 (51%) Frame = +3 Query: 267 TLIAKGKADHLQVIQHVLEQFMRKYSYFVKKIENMDTLFEAQFSPLADSGRLLSKCGKCG 446 +L GK D ++ FM++Y F+KK+ D L+ + A+ G +L+K + G Sbjct: 83 SLRESGKQDESHLLSKKYGGFMKRYGGFMKKV---DELYPVEPEEEANGGEILTK--RYG 137 Query: 447 RYMK 458 +MK Sbjct: 138 GFMK 141
>RGYR_SULSH (P74759) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1166 Score = 30.0 bits (66), Expect = 3.1 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Frame = +3 Query: 18 GSTTAPDYLSESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRR--LVPTALGTT 191 G ++ LS S++ISLM+ GIG ++ I N+ Y+ V++ R+ L+ T G Sbjct: 1049 GKGSSEQLLSYSDVISLMKSKGIGRPSTYAKTIENLVRHGYI-VSSKRKSYLIATNRG-- 1105 Query: 192 LIRGYQCIDA 221 I YQ + + Sbjct: 1106 -ISAYQFLSS 1114
>RGYR_THETN (Q8R979) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1117 Score = 29.6 bits (65), Expect = 4.0 Identities = 19/94 (20%), Positives = 46/94 (48%) Frame = +3 Query: 45 SESELISLMEKNGIGTDASIPVHINNISERNYVQVNTGRRLVPTALGTTLIRGYQCIDAD 224 +++ LI M+K IG ++ ++ + +R Y+ + +RL TALG + + Sbjct: 1016 TQASLIEEMQKRNIGRPSTYAKIVDILFKRKYIIEDVYKRLRTTALGRKVYSYLSERYMN 1075 Query: 225 LCLPDIRSFIEQQITLIAKGKADHLQVIQHVLEQ 326 + +E+ + + G+ D+ V++++ E+ Sbjct: 1076 YINEETTRQLEKLMESVETGEKDYQSVLKNLYEE 1109
>PENK_MESAU (P50175) Proenkephalin A precursor [Contains: Synenkephalin;| Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe] Length = 268 Score = 29.3 bits (64), Expect = 5.2 Identities = 19/58 (32%), Positives = 30/58 (51%) Frame = +3 Query: 285 KADHLQVIQHVLEQFMRKYSYFVKKIENMDTLFEAQFSPLADSGRLLSKCGKCGRYMK 458 K D ++ FM++Y F+KK MD L+ + A+ G +L+K K G +MK Sbjct: 89 KQDESHLLAKKYGGFMKRYGGFMKK---MDELYPVEPEEEANGGEILAK--KYGGFMK 141
>SYM_HAEDU (Q7VMC9) Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA| ligase) (MetRS) Length = 684 Score = 28.5 bits (62), Expect = 8.9 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 7/86 (8%) Frame = +3 Query: 195 IRGYQ----CIDADLCLPDIRSFIEQQIT---LIAKGKADHLQVIQHVLEQFMRKYSYFV 353 +RG+Q C D P + + +Q IT LIAK KADH+ Q F +S Sbjct: 40 MRGHQVYFVCADDAHGTPIMLNAAKQGITPEQLIAKAKADHIADFQSFNISFDNYHSTHS 99 Query: 354 KKIENMDTLFEAQFSPLADSGRLLSK 431 ++ N+ T A + L D G + ++ Sbjct: 100 EENRNITT---AMYKTLRDKGLIKTR 122 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 66,541,242 Number of Sequences: 219361 Number of extensions: 1296124 Number of successful extensions: 3340 Number of sequences better than 10.0: 66 Number of HSP's better than 10.0 without gapping: 3288 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3335 length of database: 80,573,946 effective HSP length: 103 effective length of database: 57,979,763 effective search space used: 3014947676 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
