>UBP21_MOUSE (Q9QZL6) Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 21) (Ubiquitin-specific
           processing protease 21) (Deubiquitinating enzyme 21)
          Length = 566

 Score = 33.5 bits (75), Expect = 0.15
 Identities = 19/49 (38%), Positives = 28/49 (57%)
 Frame = +3

Query: 6   KVINPTMFDQVLRNFTPDVPAGTSARPRQEHAQEFLSYAMDRMHDELLR 152
           + +NPT F  V + + P   +G S    Q+ AQEFL   M+R+H E+ R
Sbjct: 276 EAVNPTRFRAVFQKYVPSF-SGYS----QQDAQEFLKLLMERLHLEINR 319

>UBP21_HUMAN (Q9UK80) Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 21)
           (Ubiquitin-specific-processing protease 21)
           (Deubiquitinating enzyme 21) (NEDD8-specific protease)
          Length = 565

 Score = 33.5 bits (75), Expect = 0.15
 Identities = 19/49 (38%), Positives = 28/49 (57%)
 Frame = +3

Query: 6   KVINPTMFDQVLRNFTPDVPAGTSARPRQEHAQEFLSYAMDRMHDELLR 152
           + +NPT F  V + + P   +G S    Q+ AQEFL   M+R+H E+ R
Sbjct: 276 EAVNPTRFRAVFQKYVPSF-SGYS----QQDAQEFLKLLMERLHLEINR 319

>UBP7_YEAST (P40453) Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 7)
           (Ubiquitin-specific-processing protease 7)
           (Deubiquitinating enzyme 7)
          Length = 1071

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 17/43 (39%), Positives = 23/43 (53%)
 Frame = +3

Query: 18  PTMFDQVLRNFTPDVPAGTSARPRQEHAQEFLSYAMDRMHDEL 146
           PT F +V+    PD+         Q+  QEFL   +DR+HDEL
Sbjct: 681 PTGFLKVINQLRPDLKIPDD----QQDTQEFLMILLDRLHDEL 719

>UBP3_YEAST (Q01477) Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 3)
           (Ubiquitin-specific-processing protease 3)
           (Deubiquitinating enzyme 3)
          Length = 912

 Score = 32.0 bits (71), Expect = 0.45
 Identities = 15/41 (36%), Positives = 29/41 (70%), Gaps = 1/41 (2%)
 Frame = +3

Query: 90  QEHAQEFLSYAMDRMHDELL-RLNGNGLNSKEGMVVSSDDD 209
           QE A+EFL++ +D++H+EL+  ++G   N  + M+ S +D+
Sbjct: 583 QEDAEEFLTHLLDQLHEELISAIDGLTDNEIQNMLQSINDE 623

>UBP10_HUMAN (Q14694) Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 10)
           (Ubiquitin-specific-processing protease 10)
           (Deubiquitinating enzyme 10)
          Length = 798

 Score = 31.2 bits (69), Expect = 0.76
 Identities = 14/42 (33%), Positives = 26/42 (61%)
 Frame = +3

Query: 75  SARPRQEHAQEFLSYAMDRMHDELLRLNGNGLNSKEGMVVSS 200
           S + RQE A+E+L + ++ +H+E+L L      S E + +S+
Sbjct: 516 SEKGRQEDAEEYLGFILNGLHEEMLNLKKLLSPSNEKLTISN 557

>UBP2_HUMAN (O75604) Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 2)
           (Ubiquitin-specific-processing protease 2)
           (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific
           protease)
          Length = 605

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 17/67 (25%), Positives = 34/67 (50%)
 Frame = +3

Query: 9   VINPTMFDQVLRNFTPDVPAGTSARPRQEHAQEFLSYAMDRMHDELLRLNGNGLNSKEGM 188
           V++P+ F   ++ + P           Q+ AQEFL + +D +H+E+ R+     ++ E +
Sbjct: 333 VVSPSEFKTQIQRYAPRFVGYN-----QQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENL 387

Query: 189 VVSSDDD 209
               DD+
Sbjct: 388 DHLPDDE 394

>UBP10_MOUSE (P52479) Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 10)
           (Ubiquitin-specific-processing protease 10)
           (Deubiquitinating enzyme 10)
          Length = 792

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 11/32 (34%), Positives = 22/32 (68%)
 Frame = +3

Query: 60  VPAGTSARPRQEHAQEFLSYAMDRMHDELLRL 155
           + +  S + RQE A+E+L + ++ +H+E+L L
Sbjct: 505 IKSSLSEKGRQEDAEEYLGFILNGLHEEMLSL 536

>PO2F1_RAT (P31503) POU domain, class 2, transcription factor 1|
           (Octamer-binding transcription factor 1) (Oct-1) (OTF-1)
           (NF-A1) (Fragment)
          Length = 632

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 16/52 (30%), Positives = 28/52 (53%)
 Frame = -2

Query: 211 SSSSEETTIPSFEFKPLPLSLNSSSCILSMA*LRNSWACSCLGRADVPAGTS 56
           +SS+ ET+       PLP  L +S  +++ + L+ + A +  G A +PA  S
Sbjct: 426 ASSASETSTTQTTSTPLPSPLGASQVMVTASGLQTAAAAALQGAAQLPANAS 477

>CAC1H_HUMAN (O95180) Voltage-dependent T-type calcium channel alpha-1H subunit|
            (Voltage-gated calcium channel alpha subunit Cav3.2)
            (Low-voltage-activated calcium channel alpha1 3.2
            subunit)
          Length = 2353

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 14/30 (46%), Positives = 18/30 (60%)
 Frame = -2

Query: 217  QASSSSEETTIPSFEFKPLPLSLNSSSCIL 128
            QAS  +E  T+PSF F+PL L + S    L
Sbjct: 2253 QASCRAEHLTVPSFAFEPLDLGVPSGDPFL 2282

>UBP12_YEAST (P39538) Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 12)
           (Ubiquitin-specific-processing protease 12)
           (Deubiquitinating enzyme 12)
          Length = 1254

 Score = 29.3 bits (64), Expect = 2.9
 Identities = 16/65 (24%), Positives = 31/65 (47%)
 Frame = +3

Query: 18  PTMFDQVLRNFTPDVPAGTSARPRQEHAQEFLSYAMDRMHDELLRLNGNGLNSKEGMVVS 197
           P+MF   + +F         +   Q+ +QEFL++ +D +H++L R+       K  +   
Sbjct: 440 PSMFKSTIGHFN-----SMFSGYMQQDSQEFLAFLLDSLHEDLNRIIKKEYTEKPSLSPG 494

Query: 198 SDDDD 212
            D +D
Sbjct: 495 DDVND 499

>UBP2_MOUSE (O88623) Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 2)
           (Ubiquitin-specific-processing protease 2)
           (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific
           protease)
          Length = 353

 Score = 28.9 bits (63), Expect = 3.8
 Identities = 17/67 (25%), Positives = 33/67 (49%)
 Frame = +3

Query: 9   VINPTMFDQVLRNFTPDVPAGTSARPRQEHAQEFLSYAMDRMHDELLRLNGNGLNSKEGM 188
           V++P+ F   ++ + P           Q+ AQEFL + +D +H+E+ R+      S E +
Sbjct: 81  VVSPSEFKTQIQRYAPRFMGYN-----QQDAQEFLRFLLDGLHNEVNRVAARPKASPETL 135

Query: 189 VVSSDDD 209
               D++
Sbjct: 136 DHLPDEE 142

>CAC1H_MOUSE (O88427) Voltage-dependent T-type calcium channel alpha-1H subunit|
            (Voltage-gated calcium channel alpha subunit Cav3.2)
          Length = 2365

 Score = 28.9 bits (63), Expect = 3.8
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = -2

Query: 217  QASSSSEETTIPSFEFKPLPLSLNSSSCIL 128
            QAS  +E  T+P+F F+PL +      C L
Sbjct: 2266 QASCRAEHLTVPNFAFEPLDMGGPGGDCFL 2295

>RPOP_AGABT (P33539) Probable DNA-directed RNA polymerase (EC 2.7.7.6)|
          Length = 1102

 Score = 28.9 bits (63), Expect = 3.8
 Identities = 8/25 (32%), Positives = 21/25 (84%)
 Frame = +3

Query: 75  SARPRQEHAQEFLSYAMDRMHDELL 149
           S+ P++++ Q+F +YA++++ D+L+
Sbjct: 762 SSNPKEDYPQDFYTYALEKIRDKLI 786

>CAC1H_RAT (Q9EQ60) Voltage-dependent T-type calcium channel alpha-1H subunit|
            (Voltage-gated calcium channel alpha subunit Cav3.2)
          Length = 2359

 Score = 28.9 bits (63), Expect = 3.8
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = -2

Query: 217  QASSSSEETTIPSFEFKPLPLSLNSSSCIL 128
            QAS  +E  T+P+F F+PL +      C L
Sbjct: 2260 QASCRAEHLTVPNFAFEPLDMGGPGGDCFL 2289

>LSP2_DROME (Q24388) Larval serum protein 2 precursor (LSP-2) (Hexamerin 2)|
          Length = 701

 Score = 28.1 bits (61), Expect = 6.5
 Identities = 10/28 (35%), Positives = 17/28 (60%)
 Frame = -3

Query: 141 HHAFYPWHNLETLGHVLVLAEQMFQPVH 58
           HH+FY  HN E + HV +  +++   +H
Sbjct: 313 HHSFYHEHNYEHIEHVEMYTQRVMDWIH 340

>MUC5A_HUMAN (P98088) Mucin-5AC (Mucin 5 subtype AC, tracheobronchial)|
           (Tracheobronchial mucin) (TBM) (Major airway
           glycoprotein) (Fragment)
          Length = 1233

 Score = 27.7 bits (60), Expect = 8.4
 Identities = 11/19 (57%), Positives = 12/19 (63%)
 Frame = +2

Query: 59  CTGWNICSAKTRTCPRVSK 115
           C G N+ S   RTCPRV K
Sbjct: 454 CEGNNVISLSPRTCPRVEK 472

>UBP12_SCHPO (O60079) Probable ubiquitin carboxyl-terminal hydrolase 12 (EC|
           3.1.2.15) (Ubiquitin thioesterase 12)
           (Ubiquitin-specific processing protease 12)
           (Deubiquitinating enzyme 12)
          Length = 979

 Score = 27.7 bits (60), Expect = 8.4
 Identities = 11/30 (36%), Positives = 20/30 (66%)
 Frame = +3

Query: 90  QEHAQEFLSYAMDRMHDELLRLNGNGLNSK 179
           Q+ +QEFL++ +D +H++L R+      SK
Sbjct: 400 QQDSQEFLAFLLDGLHEDLNRIYQKPYTSK 429

>UBP1_SCHPO (Q9USM5) Probable ubiquitin carboxyl-terminal hydrolase 1 (EC|
           3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific
           processing protease 1) (Deubiquitinating enzyme 1)
          Length = 849

 Score = 27.7 bits (60), Expect = 8.4
 Identities = 9/23 (39%), Positives = 19/23 (82%)
 Frame = +3

Query: 87  RQEHAQEFLSYAMDRMHDELLRL 155
           RQ+ +QEF+++ +D +H++L R+
Sbjct: 368 RQQDSQEFIAFFLDGLHEDLNRI 390


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,421,156
Number of Sequences: 219361
Number of extensions: 592121
Number of successful extensions: 1673
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 1655
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1672
length of database: 80,573,946
effective HSP length: 48
effective length of database: 70,044,618
effective search space used: 1681070832
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)