ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bast43e04 |
|---|---|
| Clone Library Name | barley_pub |
>CDC2C_ANTMA (Q38774) Cell division control protein 2 homolog C (EC 2.7.11.22)| (EC 2.7.11.23) Length = 305 Score = 101 bits (252), Expect = 4e-22 Identities = 50/60 (83%), Positives = 56/60 (93%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 341 M+ YEKLEKVGEGTYGKVYKA EK+TG++VALKKTRL D+EGVPPTALREVSLL+MLSQ Sbjct: 1 MEKYEKLEKVGEGTYGKVYKALEKSTGQVVALKKTRLEMDEEGVPPTALREVSLLQMLSQ 60
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 101 bits (252), Expect = 4e-22 Identities = 50/61 (81%), Positives = 56/61 (91%) Frame = +3 Query: 159 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 AMD + KLEKVGEGTYGKVY+A EK+TG+IVALKKTRL ED+EGVPPT LREVSLLRMLS Sbjct: 10 AMDAFVKLEKVGEGTYGKVYRAMEKSTGKIVALKKTRLHEDEEGVPPTTLREVSLLRMLS 69 Query: 339 Q 341 + Sbjct: 70 R 70
>CDC2B_ARATH (P25859) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) Length = 309 Score = 99.0 bits (245), Expect = 3e-21 Identities = 47/59 (79%), Positives = 54/59 (91%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ YEKLEKVGEGTYGKVYKA EK TG++VALKKTRL D+EG+PPTALRE+SLL+MLS Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLS 59
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 84.0 bits (206), Expect = 9e-17 Identities = 38/56 (67%), Positives = 47/56 (83%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 MD YEK+EK+GEGTYG VYKAR+K T +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 84.0 bits (206), Expect = 9e-17 Identities = 38/56 (67%), Positives = 47/56 (83%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 MD YEK+EK+GEGTYG VYKAR+K T +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 83.6 bits (205), Expect = 1e-16 Identities = 41/53 (77%), Positives = 49/53 (92%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 Y+KLEK+GEGTYGKVYKA+EKATGR+VALKK RL +D+GVP TALRE+SLL+ Sbjct: 10 YQKLEKLGEGTYGKVYKAKEKATGRMVALKKIRL--EDDGVPSTALREISLLK 60
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 83.2 bits (204), Expect = 1e-16 Identities = 38/58 (65%), Positives = 48/58 (82%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 MD Y K+EK+GEGTYG VYK R KATG++VA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKEL 58
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 83.2 bits (204), Expect = 1e-16 Identities = 38/58 (65%), Positives = 48/58 (82%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 MD Y K+EK+GEGTYG VYK R KATG++VA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKEL 58
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 82.8 bits (203), Expect = 2e-16 Identities = 37/56 (66%), Positives = 48/56 (85%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M+ YEK+EK+GEGTYG VYKAR++AT +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLK 56
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 82.4 bits (202), Expect = 3e-16 Identities = 38/58 (65%), Positives = 48/58 (82%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ +EK+EK+GEGTYG VYK R + TG+IVA+KK RL DDEGVP TA+RE+SLL+ L Sbjct: 1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKEL 58
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 81.6 bits (200), Expect = 4e-16 Identities = 37/59 (62%), Positives = 49/59 (83%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ YEK+EK+GEGTYG VYKA +KAT +ALKK RL ++DEGVP TA+RE+SLL+ ++ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMN 59
>CDC2_SCHPO (P04551) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinse) Length = 297 Score = 81.6 bits (200), Expect = 4e-16 Identities = 37/56 (66%), Positives = 48/56 (85%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M+ Y+K+EK+GEGTYG VYKAR K +GRIVA+KK RL ++ EGVP TA+RE+SLL+ Sbjct: 1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLK 56
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 81.3 bits (199), Expect = 6e-16 Identities = 38/58 (65%), Positives = 49/58 (84%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 MD+++K+EK+GEGTYG VYKAR K TG++VALKK RL + EGVP TA+RE+SLL+ L Sbjct: 1 MDVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKEL 58
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 81.3 bits (199), Expect = 6e-16 Identities = 36/56 (64%), Positives = 47/56 (83%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M+ YEK+EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 81.3 bits (199), Expect = 6e-16 Identities = 36/56 (64%), Positives = 47/56 (83%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M+ YEK+EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 80.9 bits (198), Expect = 7e-16 Identities = 36/56 (64%), Positives = 47/56 (83%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M+ YEK+EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLK 56
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 80.5 bits (197), Expect = 1e-15 Identities = 38/58 (65%), Positives = 47/58 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 MD Y K+EK+GEGTYG VYK KATG+IVA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MDEYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKEL 58
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 80.1 bits (196), Expect = 1e-15 Identities = 37/58 (63%), Positives = 47/58 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 MD Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKEL 58
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 79.7 bits (195), Expect = 2e-15 Identities = 37/59 (62%), Positives = 48/59 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ ++K+EK+GEGTYG VYKAR K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 79.7 bits (195), Expect = 2e-15 Identities = 36/58 (62%), Positives = 47/58 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL 58
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 79.7 bits (195), Expect = 2e-15 Identities = 36/58 (62%), Positives = 47/58 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL 58
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 79.7 bits (195), Expect = 2e-15 Identities = 36/58 (62%), Positives = 47/58 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG VYK R K TG++VA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL 58
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 79.7 bits (195), Expect = 2e-15 Identities = 36/56 (64%), Positives = 46/56 (82%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M+ YEK EK+GEGTYG VY+AR+K T +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 1 MEQYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 79.3 bits (194), Expect = 2e-15 Identities = 37/58 (63%), Positives = 48/58 (82%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL 58
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 79.3 bits (194), Expect = 2e-15 Identities = 37/58 (63%), Positives = 48/58 (82%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL 58
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 79.3 bits (194), Expect = 2e-15 Identities = 37/58 (63%), Positives = 48/58 (82%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL 58
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 79.3 bits (194), Expect = 2e-15 Identities = 37/58 (63%), Positives = 48/58 (82%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG VYK R K+TG++VA+KK RL ++EGVP TA+REVSLL+ L Sbjct: 1 MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQEL 58
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 79.0 bits (193), Expect = 3e-15 Identities = 36/58 (62%), Positives = 49/58 (84%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 MD+++K+EK+GEGTYG VYKA+ + TG++VALKK RL + EGVP TA+RE+SLL+ L Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKEL 58
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 79.0 bits (193), Expect = 3e-15 Identities = 37/59 (62%), Positives = 48/59 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ ++K+EK+GEGTYG VYKAR + TG IVALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELN 59
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 78.6 bits (192), Expect = 4e-15 Identities = 36/59 (61%), Positives = 48/59 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 78.6 bits (192), Expect = 4e-15 Identities = 36/59 (61%), Positives = 48/59 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 78.6 bits (192), Expect = 4e-15 Identities = 36/59 (61%), Positives = 48/59 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 78.6 bits (192), Expect = 4e-15 Identities = 36/59 (61%), Positives = 48/59 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 78.6 bits (192), Expect = 4e-15 Identities = 36/59 (61%), Positives = 48/59 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ ++K+EK+GEGTYG VYKA+ K TG +VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 78.6 bits (192), Expect = 4e-15 Identities = 37/58 (63%), Positives = 46/58 (79%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL 58
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 78.6 bits (192), Expect = 4e-15 Identities = 37/58 (63%), Positives = 46/58 (79%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL 58
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 78.6 bits (192), Expect = 4e-15 Identities = 37/58 (63%), Positives = 46/58 (79%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL 58
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 78.6 bits (192), Expect = 4e-15 Identities = 37/58 (63%), Positives = 46/58 (79%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKEL 58
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 78.2 bits (191), Expect = 5e-15 Identities = 36/58 (62%), Positives = 47/58 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG VYK R + TG+IVA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKEL 58
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 78.2 bits (191), Expect = 5e-15 Identities = 35/58 (60%), Positives = 46/58 (79%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG VYK R K TG++V +KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKEL 58
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 78.2 bits (191), Expect = 5e-15 Identities = 36/58 (62%), Positives = 47/58 (81%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG VYK R + TG+IVA+KK RL ++EGVP TA+RE+SLL+ L Sbjct: 1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKEL 58
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 78.2 bits (191), Expect = 5e-15 Identities = 37/58 (63%), Positives = 46/58 (79%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M YEKLEK+GEGTYG V+KA+ + T IVALK+ RL +DDEGVP +ALRE+ LL+ L Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKEL 58
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 77.8 bits (190), Expect = 6e-15 Identities = 36/59 (61%), Positives = 47/59 (79%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ ++K+EK+GEGTYG VYKA+ K TG VALKK RL + EGVP TA+RE+SLL+ L+ Sbjct: 1 MESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELN 59
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 77.0 bits (188), Expect = 1e-14 Identities = 34/56 (60%), Positives = 45/56 (80%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M+ YEK+EK+GEGTYG VYK + + T +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 1 MEQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLK 56
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 76.6 bits (187), Expect = 1e-14 Identities = 36/58 (62%), Positives = 45/58 (77%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M Y+K+EK+GEGTYG V+K R + T IVALK+ RL EDDEGVP +ALRE+ LL+ L Sbjct: 1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKEL 58
>CDC2_EMENI (Q00646) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 323 Score = 76.3 bits (186), Expect = 2e-14 Identities = 38/60 (63%), Positives = 48/60 (80%), Gaps = 1/60 (1%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKA-TGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 M+ Y+K+EK+GEGTYG VYKARE RIVALKK RL +DEGVP TA+RE+SLL+ ++ Sbjct: 1 MENYQKIEKIGEGTYGVVYKARELTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMN 60
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 75.5 bits (184), Expect = 3e-14 Identities = 36/58 (62%), Positives = 46/58 (79%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y K+EK+GEGTYG V KA+ + TG IVALK+ RL +DEGVP TA+RE+SLL+ L Sbjct: 1 MEKYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKEL 58
>CDC2_AJECA (P54119) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 324 Score = 74.7 bits (182), Expect = 5e-14 Identities = 37/57 (64%), Positives = 46/57 (80%), Gaps = 1/57 (1%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKA-TGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M+ Y+K+EK+GEGTYG VYKAR+ RIVALKK RL +DEGVP TA+RE+SLL+ Sbjct: 1 MENYQKIEKIGEGTYGVVYKARDLTHPNRIVALKKIRLEAEDEGVPSTAIREISLLK 57
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 74.7 bits (182), Expect = 5e-14 Identities = 33/52 (63%), Positives = 43/52 (82%) Frame = +3 Query: 174 EKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 E +EK+GEGTYG VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 2 ENVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLK 53
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 73.9 bits (180), Expect = 9e-14 Identities = 35/58 (60%), Positives = 46/58 (79%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 +D +++ EK+GEGTYG VYKAR +TG+ VALKK RL + EGVP TA+RE+SLL+ L Sbjct: 5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL 62
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 73.6 bits (179), Expect = 1e-13 Identities = 34/55 (61%), Positives = 45/55 (81%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 D Y +++ +GEGTYG VY+A ++ATG+IVALKK RL DEG+P TALREVS+L+ Sbjct: 21 DRYNRMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQ 75
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 72.8 bits (177), Expect = 2e-13 Identities = 34/55 (61%), Positives = 44/55 (80%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YE+ EK+GEGTYG VYKAR+ +T VALK+ RL ++EGVP TA+RE+SLL+ L Sbjct: 5 YERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKEL 59
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 72.4 bits (176), Expect = 3e-13 Identities = 33/55 (60%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 + KLEK+GEGTYG VYK + + T +VA+KK RL +DEGVP TA+RE+SLL+ L Sbjct: 22 FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKEL 76
>CDC28_YEAST (P00546) Cell division control protein 28 (EC 2.7.11.22)| Length = 298 Score = 72.0 bits (175), Expect = 3e-13 Identities = 37/58 (63%), Positives = 45/58 (77%), Gaps = 3/58 (5%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATG---RIVALKKTRLPEDDEGVPPTALREVSLLRML 335 Y++LEKVGEGTYG VYKA + G R+VALKK RL +DEGVP TA+RE+SLL+ L Sbjct: 8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKEL 65
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 72.0 bits (175), Expect = 3e-13 Identities = 33/61 (54%), Positives = 46/61 (75%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 R +D ++ + +GEGTYG+VYKAR+K TG +VALKK RL + EG P TA+RE+ +LR L Sbjct: 700 RCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQL 759 Query: 336 S 338 + Sbjct: 760 T 760
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 72.0 bits (175), Expect = 3e-13 Identities = 33/60 (55%), Positives = 45/60 (75%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 R +D ++ + +GEGTYG+VYKAR+K TG +VALKK RL + EG P TA+RE+ +LR L Sbjct: 722 RCVDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQL 781
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 72.0 bits (175), Expect = 3e-13 Identities = 33/61 (54%), Positives = 46/61 (75%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 R +D ++ + +GEGTYG+VYKAR+K TG +VALKK RL + EG P TA+RE+ +LR L Sbjct: 700 RCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQL 759 Query: 336 S 338 + Sbjct: 760 T 760
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 71.6 bits (174), Expect = 4e-13 Identities = 31/55 (56%), Positives = 47/55 (85%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YE+L+K+GEG+YG V++AR+ TG IVA+K+ RL +++EGVP TA+RE+S+L+ L Sbjct: 5 YERLQKIGEGSYGVVFRARDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKEL 59
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 70.9 bits (172), Expect = 8e-13 Identities = 35/58 (60%), Positives = 44/58 (75%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M Y K+EK+GEGTYG VYKA+ G I ALKK R+ E+DEG+P TA+RE+SLL+ L Sbjct: 1 MRRYHKMEKIGEGTYGVVYKAQNNH-GEICALKKIRVEEEDEGIPSTAIREISLLKEL 57
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 70.9 bits (172), Expect = 8e-13 Identities = 35/58 (60%), Positives = 44/58 (75%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M Y K+EK+GEGTYG VYKA+ G I ALKK R+ E+DEG+P TA+RE+SLL+ L Sbjct: 1 MRRYHKMEKIGEGTYGVVYKAQNNH-GEICALKKIRVEEEDEGIPSTAIREISLLKEL 57
>CDK9_CAEEL (Q9TVL3) Probable cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 478 Score = 70.9 bits (172), Expect = 8e-13 Identities = 34/61 (55%), Positives = 45/61 (73%) Frame = +3 Query: 153 LRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 332 +R + YEKL K+G+GT+G+V+KAR K TGR+VALKK + + EG P TALREV +L Sbjct: 79 IRDVSTYEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQ 138 Query: 333 L 335 L Sbjct: 139 L 139
>CDC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.11.22)| Length = 317 Score = 70.5 bits (171), Expect = 1e-12 Identities = 35/54 (64%), Positives = 43/54 (79%), Gaps = 1/54 (1%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKARE-KATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 Y++ EKVGEGTYG VYKA + K R+VALKK RL +DEGVP TA+RE+SLL+ Sbjct: 7 YQRQEKVGEGTYGVVYKALDTKHNNRVVALKKIRLESEDEGVPSTAIREISLLK 60
>CC2H2_TRYBB (P54665) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 345 Score = 68.6 bits (166), Expect = 4e-12 Identities = 34/58 (58%), Positives = 43/58 (74%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 D Y ++EKVGEG+YG VYK + TGR VA+K+ L +D GVP TA+REVSLLR L+ Sbjct: 44 DRYSRIEKVGEGSYGIVYKCHDNFTGRTVAMKRIPLIVNDGGVPSTAVREVSLLRELN 101
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 68.2 bits (165), Expect = 5e-12 Identities = 32/55 (58%), Positives = 44/55 (80%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 Y++LEK+GEG+YG VY+AR+ T IVALK+ RL +EGVP TA+RE+S+L+ L Sbjct: 5 YQRLEKIGEGSYGVVYRARDITTDVIVALKRIRLESVEEGVPCTAIREISILKEL 59
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 68.2 bits (165), Expect = 5e-12 Identities = 33/58 (56%), Positives = 44/58 (75%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y LEK+GEGTYG VYKA + + G ALKK RL ++DEG+P TA+RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKA-QNSDGESFALKKIRLEKEDEGIPSTAIREISILKEL 57
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 68.2 bits (165), Expect = 5e-12 Identities = 33/58 (56%), Positives = 44/58 (75%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y LEK+GEGTYG VYKA + + G ALKK RL ++DEG+P TA+RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKA-QNSDGESFALKKIRLEKEDEGIPSTAIREISILKEL 57
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 67.4 bits (163), Expect = 8e-12 Identities = 36/58 (62%), Positives = 43/58 (74%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y KLEK+GEGTY VYK R K T +VALK+ RL E +EG P TA+REVSLL+ L Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKDL 245
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 67.4 bits (163), Expect = 8e-12 Identities = 36/58 (62%), Positives = 43/58 (74%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y KLEK+GEGTY VYK R K T +VALK+ RL E +EG P TA+REVSLL+ L Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKDL 245
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 67.4 bits (163), Expect = 8e-12 Identities = 36/58 (62%), Positives = 43/58 (74%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y KLEK+GEGTY VYK R K T +VALK+ RL E +EG P TA+REVSLL+ L Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKDL 245
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 67.4 bits (163), Expect = 8e-12 Identities = 33/58 (56%), Positives = 43/58 (74%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P TA+RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTAIREISILKEL 57
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 67.4 bits (163), Expect = 8e-12 Identities = 33/58 (56%), Positives = 43/58 (74%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P TA+RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTAIREISILKEL 57
>CDK9_HUMAN (P50750) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4) Length = 372 Score = 67.4 bits (163), Expect = 8e-12 Identities = 30/55 (54%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YEKL K+G+GT+G+V+KAR + TG+ VALKK + + EG P TALRE+ +L++L Sbjct: 19 YEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLL 73
>BUR1_ASPFU (Q4WTN5) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 580 Score = 67.0 bits (162), Expect = 1e-11 Identities = 33/56 (58%), Positives = 42/56 (75%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 +E L K+GEGT+G+VYKAR K G IVALKK + + +G P TALRE+ LL+MLS Sbjct: 25 FEFLGKLGEGTFGEVYKARSKKDGSIVALKKILMHNEKDGFPITALREIKLLKMLS 80
>CDK9_CHICK (Q5ZKN1) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 66.6 bits (161), Expect = 1e-11 Identities = 29/55 (52%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLL 73
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 66.6 bits (161), Expect = 1e-11 Identities = 30/60 (50%), Positives = 46/60 (76%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 R++ +EKL ++GEGTYG VY+AR+ T IVALKK R+ ++ +G+P ++LRE++LL L Sbjct: 34 RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL 93
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 66.2 bits (160), Expect = 2e-11 Identities = 33/57 (57%), Positives = 43/57 (75%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 D YEKLEK+GEG+Y VYK + K G++VALK RL +++EG P TA+RE SLL+ L Sbjct: 133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRL-QEEEGTPFTAIREASLLKGL 188
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 66.2 bits (160), Expect = 2e-11 Identities = 33/57 (57%), Positives = 43/57 (75%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 D YEKLEK+GEG+Y VYK + K G++VALK RL +++EG P TA+RE SLL+ L Sbjct: 133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRL-QEEEGTPFTAIREASLLKGL 188
>CDK9_RAT (Q641Z4) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 66.2 bits (160), Expect = 2e-11 Identities = 29/55 (52%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLL 73
>CDK9_MOUSE (Q99J95) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 66.2 bits (160), Expect = 2e-11 Identities = 29/55 (52%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLL 73
>CDK9_BOVIN (Q5EAB2) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 66.2 bits (160), Expect = 2e-11 Identities = 29/55 (52%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YEKL K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L Sbjct: 19 YEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFPITALREIKILQLL 73
>BUR1_EMENI (Q96VK3) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) (Pitalre-like kinase A) Length = 544 Score = 66.2 bits (160), Expect = 2e-11 Identities = 33/56 (58%), Positives = 42/56 (75%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 +E L K+GEGT+G+VYKAR K G IVALKK + + +G P TALRE+ LL+MLS Sbjct: 25 FEFLGKLGEGTFGEVYKARAKRDGSIVALKKILMHNERDGFPITALREIKLLKMLS 80
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 65.9 bits (159), Expect = 2e-11 Identities = 32/58 (55%), Positives = 42/58 (72%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P T +RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTTIREISILKEL 57
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 65.9 bits (159), Expect = 2e-11 Identities = 32/58 (55%), Positives = 42/58 (72%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y LEK+GEGTYG VYKA+ G ALKK RL ++DEG+P T +RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTTIREISILKEL 57
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 65.5 bits (158), Expect = 3e-11 Identities = 39/86 (45%), Positives = 50/86 (58%), Gaps = 7/86 (8%) Frame = +3 Query: 99 LQHQNQGAAAPMXXXXXXLRAMDL-------YEKLEKVGEGTYGKVYKAREKATGRIVAL 257 LQ +N G P+ D+ Y KL+K+GEGTY V+K R K T +VAL Sbjct: 90 LQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVAL 149 Query: 258 KKTRLPEDDEGVPPTALREVSLLRML 335 K+ RL E +EG P TA+REVSLL+ L Sbjct: 150 KEIRL-EHEEGAPCTAIREVSLLKDL 174
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 65.5 bits (158), Expect = 3e-11 Identities = 39/86 (45%), Positives = 50/86 (58%), Gaps = 7/86 (8%) Frame = +3 Query: 99 LQHQNQGAAAPMXXXXXXLRAMDL-------YEKLEKVGEGTYGKVYKAREKATGRIVAL 257 LQ +N G P+ D+ Y KL+K+GEGTY V+K R K T +VAL Sbjct: 90 LQLENPGLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVAL 149 Query: 258 KKTRLPEDDEGVPPTALREVSLLRML 335 K+ RL E +EG P TA+REVSLL+ L Sbjct: 150 KEIRL-EHEEGAPCTAIREVSLLKDL 174
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 65.5 bits (158), Expect = 3e-11 Identities = 31/55 (56%), Positives = 42/55 (76%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 Y++LEK+GEGTY VYK + + TG IVALK R+ + DEG P TA+RE+SL++ L Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRI-DADEGTPSTAIREISLMKEL 56
>CDK9_XENTR (Q6GLD8) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 376 Score = 65.5 bits (158), Expect = 3e-11 Identities = 28/55 (50%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YE+L K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L Sbjct: 19 YERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLL 73
>CDK9B_XENLA (Q7ZX42) Cell division protein kinase 9-B (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-B) Length = 376 Score = 65.5 bits (158), Expect = 3e-11 Identities = 28/55 (50%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YE+L K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L Sbjct: 19 YERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLL 73
>CDK9A_XENLA (Q4V862) Cell division protein kinase 9-A (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-A) Length = 376 Score = 65.5 bits (158), Expect = 3e-11 Identities = 28/55 (50%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YE+L K+G+GT+G+V+KA+ + TG+ VALKK + + EG P TALRE+ +L++L Sbjct: 19 YERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLL 73
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 64.7 bits (156), Expect = 5e-11 Identities = 34/69 (49%), Positives = 45/69 (65%) Frame = +3 Query: 129 PMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTAL 308 P+ ++ Y KL+K+GEGTY VYK + K T +VALK+ RL E +EG P TA+ Sbjct: 151 PVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAI 209 Query: 309 REVSLLRML 335 REVSLL+ L Sbjct: 210 REVSLLKDL 218
>CD2L7_CAEEL (P46551) Putative cell division cycle 2-related protein kinase 7| (EC 2.7.11.22) Length = 730 Score = 64.7 bits (156), Expect = 5e-11 Identities = 30/55 (54%), Positives = 39/55 (70%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 Y L+++GEGTYG+VYKA TG VALK+ RL + EG P TA+RE+ +LR L Sbjct: 311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQL 365
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 64.3 bits (155), Expect = 7e-11 Identities = 33/58 (56%), Positives = 43/58 (74%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 ++ Y KL+K+GEGTY VYK + K T +VALK+ RL E +EG P TA+REVSLL+ L Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAIREVSLLKDL 218
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 64.3 bits (155), Expect = 7e-11 Identities = 33/58 (56%), Positives = 43/58 (74%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 ++ Y KL+K+GEGTY VYK + K T +VALK+ RL E +EG P TA+REVSLL+ L Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRL-EHEEGAPCTAIREVSLLKDL 218
>BUR1_NEUCR (Q871M9) Serine/threonine-protein kinase bur-1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 545 Score = 64.3 bits (155), Expect = 7e-11 Identities = 30/56 (53%), Positives = 43/56 (76%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 YE L K+GEGT+G+V++AR + TG +VALKK + + +G P TALRE+ LL++LS Sbjct: 26 YEVLGKLGEGTFGEVHRARSRKTGALVALKKIIMHNERDGFPITALREIKLLKLLS 81
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 64.3 bits (155), Expect = 7e-11 Identities = 30/55 (54%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 +++LEK+GEGTY VYK R +ATG +VALK+ L + +EG P TA+RE+SL++ L Sbjct: 8 FQQLEKLGEGTYATVYKGRNRATGALVALKEISL-DSEEGTPSTAIREISLMKEL 61
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 64.3 bits (155), Expect = 7e-11 Identities = 33/58 (56%), Positives = 43/58 (74%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 ++ Y KL+K+GEGTY V+K R K T +VALK+ RL E +EG P TA+REVSLL+ L Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRL-EHEEGAPCTAIREVSLLKNL 195
>CTK1_YEAST (Q03957) CTD kinase subunit alpha (EC 2.7.11.23) (CTD kinase 58 kDa| subunit) (CTDK-I alpha subunit) Length = 528 Score = 63.9 bits (154), Expect = 9e-11 Identities = 30/58 (51%), Positives = 43/58 (74%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 R+ +Y ++ +VGEGTYGKVYKA+ T ++VALKK RL + EG P T++RE+ LL+ Sbjct: 178 RSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQ 235
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 63.9 bits (154), Expect = 9e-11 Identities = 29/55 (52%), Positives = 43/55 (78%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 +++LEK+GEGTY VYK R + TG++VALK+ L + +EG P TA+RE+SL++ L Sbjct: 7 FQQLEKLGEGTYATVYKGRNRTTGQLVALKEINL-DSEEGTPSTAIREISLMKEL 60
>BUR1_GIBZE (Q4I5U9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 473 Score = 63.5 bits (153), Expect = 1e-10 Identities = 30/56 (53%), Positives = 43/56 (76%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 YE L K+GEGT+G+V++AR + TG +VALKK + + +G P TALRE+ LL++LS Sbjct: 37 YELLGKLGEGTFGEVHRARLRKTGALVALKKIIMHHEKDGFPITALREIKLLKLLS 92
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 63.5 bits (153), Expect = 1e-10 Identities = 30/58 (51%), Positives = 42/58 (72%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YEKL K+GEG+YG V+K R K++G++VA+KK EDD V ALRE+ +L+ L Sbjct: 1 MEKYEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQL 58
>CDC2H_CRIFA (Q01917) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 474 Score = 63.2 bits (152), Expect = 2e-10 Identities = 29/55 (52%), Positives = 38/55 (69%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 Y + K+GEGTYG VYK E TGR+VA K+ + DDEG+P A+RE+ LL+ L Sbjct: 7 YRHVVKLGEGTYGMVYKGTEIQTGRVVAFKRMVVTSDDEGIPGAAIREICLLKEL 61
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 63.2 bits (152), Expect = 2e-10 Identities = 30/58 (51%), Positives = 41/58 (70%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YEK+ K+GEG+YG V+K R K TG+IVA+KK EDD + ALRE+ +L+ L Sbjct: 1 MEKYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQL 58
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 62.4 bits (150), Expect = 3e-10 Identities = 32/59 (54%), Positives = 44/59 (74%), Gaps = 1/59 (1%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPT-ALREVSLLRML 335 M+ Y LEK+GEGTYG VYKA + + G ALKK RL ++DEG+P T ++RE+S+L+ L Sbjct: 1 MEKYHGLEKIGEGTYGVVYKA-QNSDGESFALKKIRLEKEDEGIPSTVSIREISILKEL 58
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 62.0 bits (149), Expect = 4e-10 Identities = 29/58 (50%), Positives = 41/58 (70%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YEK+ K+GEG+YG V+K R + TG+IVA+KK EDD + ALRE+ +L+ L Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQL 58
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 62.0 bits (149), Expect = 4e-10 Identities = 28/55 (50%), Positives = 42/55 (76%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 +++LEK+GEGTY VYK R + G++VALK+ L + +EG P TA+RE+SL++ L Sbjct: 8 FQQLEKLGEGTYATVYKGRNRTNGQLVALKEINL-DSEEGTPSTAIREISLMKEL 61
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 62.0 bits (149), Expect = 4e-10 Identities = 32/58 (55%), Positives = 42/58 (72%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 ++ Y KL+K+GEGTY V+K R K +VALK+ RL E +EG P TA+REVSLL+ L Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLMENLVALKEIRL-EHEEGAPCTAIREVSLLKNL 195
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 61.6 bits (148), Expect = 5e-10 Identities = 30/58 (51%), Positives = 40/58 (68%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YEKL K GEG+YG V+K R K +G++VA+KK EDD V ALRE+ +L+ L Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQL 58
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 60.8 bits (146), Expect = 8e-10 Identities = 28/58 (48%), Positives = 41/58 (70%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YEK+ K+GEG+YG V+K R + TG+IVA+K+ EDD + ALRE+ +L+ L Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQL 58
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 60.8 bits (146), Expect = 8e-10 Identities = 28/58 (48%), Positives = 41/58 (70%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YEK+ K+GEG+YG V+K R + TG+IVA+K+ EDD + ALRE+ +L+ L Sbjct: 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQL 58
>CDK6_MOUSE (Q64261) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) (CRK2) Length = 326 Score = 60.8 bits (146), Expect = 8e-10 Identities = 31/61 (50%), Positives = 44/61 (72%), Gaps = 1/61 (1%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKARE-KATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 332 RA YE + ++GEG YGKV+KAR+ K GR VALK+ R+ +EG+P + +REV++LR Sbjct: 8 RADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIREVAVLRH 67 Query: 333 L 335 L Sbjct: 68 L 68
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 60.5 bits (145), Expect = 1e-09 Identities = 33/60 (55%), Positives = 40/60 (66%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 R D Y K E +GEGTYG V+KA + TG VA+KK RL + EGV TALRE+ LL+ L Sbjct: 14 RVADRYLKREVLGEGTYGVVFKAVDTKTGNTVAIKKIRLGKYKEGVNFTALREIKLLKEL 73
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 60.5 bits (145), Expect = 1e-09 Identities = 31/58 (53%), Positives = 39/58 (67%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YE L VGEG+YG V K R K TGRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58
>CDK6_HUMAN (Q00534) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) Length = 326 Score = 60.5 bits (145), Expect = 1e-09 Identities = 31/61 (50%), Positives = 44/61 (72%), Gaps = 1/61 (1%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKARE-KATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 332 RA YE + ++GEG YGKV+KAR+ K GR VALK+ R+ +EG+P + +REV++LR Sbjct: 8 RADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRH 67 Query: 333 L 335 L Sbjct: 68 L 68
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 60.5 bits (145), Expect = 1e-09 Identities = 31/58 (53%), Positives = 39/58 (67%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YE L VGEG+YG V K R K TGRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 60.5 bits (145), Expect = 1e-09 Identities = 31/58 (53%), Positives = 39/58 (67%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YE L VGEG+YG V K R K TGRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 60.1 bits (144), Expect = 1e-09 Identities = 32/59 (54%), Positives = 43/59 (72%), Gaps = 3/59 (5%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLS 338 YEKL+ +GEG + VYKAR+K T RIVA+KK +L E ++G+ TALRE+ LL+ LS Sbjct: 18 YEKLDFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEANDGINRTALREIKLLQELS 76
>YP62_CAEEL (Q09437) Putative serine/threonine-protein kinase B0495.2 (EC| 2.7.11.1) Length = 719 Score = 60.1 bits (144), Expect = 1e-09 Identities = 27/57 (47%), Positives = 42/57 (73%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R +D YE + +V EGT+G VY+ ++K T IVALK+ ++ ++ EG P TALRE+++L Sbjct: 351 RNIDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINML 407
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 59.7 bits (143), Expect = 2e-09 Identities = 29/55 (52%), Positives = 40/55 (72%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 +++LEKVG GTY VYK K TG VALK+ +L + +EG P TA+RE+SL++ L Sbjct: 7 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKEL 60
>BUR1_YARLI (Q6C842) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 706 Score = 59.3 bits (142), Expect = 2e-09 Identities = 28/55 (50%), Positives = 40/55 (72%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 Y+ L K+GEGT+G+V++A + T R VALKK L + EG P TALRE+ +L++L Sbjct: 38 YKPLGKIGEGTFGEVFRAEQITTKRHVALKKILLHSEKEGFPVTALREIRILKLL 92
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 58.9 bits (141), Expect = 3e-09 Identities = 30/58 (51%), Positives = 39/58 (67%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YE L VGEG+YG V K R K +GRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 58.9 bits (141), Expect = 3e-09 Identities = 30/58 (51%), Positives = 39/58 (67%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YE L VGEG+YG V K R K +GRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 58.9 bits (141), Expect = 3e-09 Identities = 30/58 (51%), Positives = 39/58 (67%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ YE L VGEG+YG V K R K +GRIVA+KK +DD+ V A+RE+ LL+ L Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQL 58
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 58.9 bits (141), Expect = 3e-09 Identities = 28/55 (50%), Positives = 41/55 (74%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 +++LEK+G GTY VYK K+TG VALK+ +L + +EG P TA+RE+SL++ L Sbjct: 6 FKQLEKLGNGTYATVYKGLNKSTGVYVALKEVKL-DSEEGTPSTAIREISLMKEL 59
>KP58_DROME (Q9VPC0) Serine/threonine-protein kinase PITSLRE (EC 2.7.11.22)| (Cell division cycle 2-like) Length = 952 Score = 58.5 bits (140), Expect = 4e-09 Identities = 25/57 (43%), Positives = 43/57 (75%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ L Sbjct: 553 RSVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTL 609
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 58.5 bits (140), Expect = 4e-09 Identities = 28/55 (50%), Positives = 40/55 (72%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 +++LEK+G GTY VYK K TG VALK+ +L + +EG P TA+RE+SL++ L Sbjct: 7 FKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKEL 60
>CDK7_CARAU (P51953) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 344 Score = 58.5 bits (140), Expect = 4e-09 Identities = 31/60 (51%), Positives = 42/60 (70%), Gaps = 3/60 (5%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLS 338 LYEKL+ +GEG + VYKAR+K T IVA+KK ++ E +G+ TALRE+ LL+ LS Sbjct: 11 LYEKLDFLGEGQFATVYKARDKTTNTIVAIKKIKVGHRTEAKDGINRTALREIKLLQELS 70
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 58.2 bits (139), Expect = 5e-09 Identities = 31/59 (52%), Positives = 42/59 (71%), Gaps = 3/59 (5%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLS 338 YEKL+ +GEG + VYKAR+K T +IVA+KK +L E +G+ TALRE+ LL+ LS Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 58.2 bits (139), Expect = 5e-09 Identities = 31/59 (52%), Positives = 42/59 (71%), Gaps = 3/59 (5%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLS 338 YEKL+ +GEG + VYKAR+K T +IVA+KK +L E +G+ TALRE+ LL+ LS Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 57.8 bits (138), Expect = 7e-09 Identities = 27/55 (49%), Positives = 40/55 (72%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 +++LE++G GTY VYK K TG VALK+ +L + +EG P TA+RE+SL++ L Sbjct: 9 FKQLERLGNGTYATVYKGLNKTTGLYVALKEVKL-DSEEGTPSTAIREISLMKEL 62
>CD2L1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1) Length = 795 Score = 57.4 bits (137), Expect = 9e-09 Identities = 24/57 (42%), Positives = 43/57 (75%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ + Sbjct: 433 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTI 489
>CDK9_SCHPO (Q96WV9) Serine/threonine-protein kinase cdk9 (EC 2.7.11.1)| (Cyclin-dependent kinase cdk9) Length = 591 Score = 57.4 bits (137), Expect = 9e-09 Identities = 23/55 (41%), Positives = 40/55 (72%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 Y +EK+GEGT+G+VYK++ + G++ ALK+ + + EG P TA+RE+ +L+ + Sbjct: 36 YHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSI 90
>CD2L1_MOUSE (P24788) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 784 Score = 57.4 bits (137), Expect = 9e-09 Identities = 24/57 (42%), Positives = 43/57 (75%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ + Sbjct: 422 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTI 478
>CD2L2_HUMAN (Q9UQ88) PITSLRE serine/threonine-protein kinase CDC2L2 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11) Length = 780 Score = 57.4 bits (137), Expect = 9e-09 Identities = 24/57 (42%), Positives = 43/57 (75%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T+LRE++ + Sbjct: 418 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTI 474
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 57.0 bits (136), Expect = 1e-08 Identities = 26/55 (47%), Positives = 39/55 (70%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 M YEK +++GEGTYG V KA + R VALKK + +D+G+P T++RE+++L Sbjct: 1 MTRYEKKQQLGEGTYGVVCKAWDTVCNRYVALKKIKQEREDDGIPVTSVREIAVL 55
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 56.6 bits (135), Expect = 1e-08 Identities = 25/55 (45%), Positives = 39/55 (70%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 YE + ++G G YG VYKAR+ +G+ VALK R+ ++ G+P + +REV+LL+ L Sbjct: 9 YEPVAEIGVGAYGTVYKARDLQSGKFVALKNVRVQTNENGLPLSTVREVTLLKRL 63
>CD2L1_RAT (P46892) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 436 Score = 56.6 bits (135), Expect = 1e-08 Identities = 23/57 (40%), Positives = 43/57 (75%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R+++ ++ L ++ EGTYG VY+A++K T IVALK+ ++ ++ EG P T++RE++ + Sbjct: 74 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPLTSIREINTI 130
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 55.8 bits (133), Expect = 3e-08 Identities = 26/42 (61%), Positives = 33/42 (78%) Frame = +3 Query: 204 YGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 YG VYKAR+ T +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 2 YGVVYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLK 43
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 55.5 bits (132), Expect = 3e-08 Identities = 30/60 (50%), Positives = 38/60 (63%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 341 M+ +E L VGEG YG V K R K T IVA+KK + E++E V T LRE+ +LR L Q Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 55.5 bits (132), Expect = 3e-08 Identities = 30/58 (51%), Positives = 41/58 (70%), Gaps = 3/58 (5%) Frame = +3 Query: 174 EKLEKVGEGTYGKVYKAREKATGRIVALKKTRL---PEDDEGVPPTALREVSLLRMLS 338 EKL+ +GEG + VYKAR+K T +IVA+KK +L E +G+ TALRE+ LL+ LS Sbjct: 5 EKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 62
>CDC21_PEA (P19026) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34) (Fragment) Length = 148 Score = 54.7 bits (130), Expect = 6e-08 Identities = 24/39 (61%), Positives = 32/39 (82%) Frame = +3 Query: 213 VYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 VYKAR++ T +ALKK RL ++DEGVP TA+RE+SLL+ Sbjct: 2 VYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLK 40
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 54.3 bits (129), Expect = 7e-08 Identities = 27/56 (48%), Positives = 37/56 (66%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G+P ALRE+ L+ Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQ 56
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 54.3 bits (129), Expect = 7e-08 Identities = 27/56 (48%), Positives = 37/56 (66%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G+P ALRE+ L+ Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQ 56
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 54.3 bits (129), Expect = 7e-08 Identities = 27/56 (48%), Positives = 37/56 (66%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G+P ALRE+ L+ Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQ 56
>BUR1_CANAL (Q9Y7W4) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 746 Score = 54.3 bits (129), Expect = 7e-08 Identities = 25/56 (44%), Positives = 39/56 (69%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 YE +EK+G+GT+G V KA+ K G +VA+K+ EG P TA+RE+++L+ L+ Sbjct: 44 YEVIEKLGQGTFGVVQKAKSKKDGSLVAIKQLINHSAKEGFPITAMREITILKQLN 99
>CDK4_RAT (P35426) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 53.1 bits (126), Expect = 2e-07 Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 3/58 (5%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDE---GVPPTALREVSLLRML 335 YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR L Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRL 63
>CDK4_MOUSE (P30285) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) (CRK3) Length = 303 Score = 53.1 bits (126), Expect = 2e-07 Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 3/58 (5%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDE---GVPPTALREVSLLRML 335 YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR L Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRL 63
>CCRK_MACMU (Q5EDC3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 243 Score = 52.8 bits (125), Expect = 2e-07 Identities = 27/56 (48%), Positives = 36/56 (64%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G P ALRE+ L+ Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQ 56
>CDK4_PIG (P79432) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 303 Score = 52.8 bits (125), Expect = 2e-07 Identities = 28/62 (45%), Positives = 38/62 (61%), Gaps = 3/62 (4%) Frame = +3 Query: 159 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPED---DEGVPPTALREVSLLR 329 A YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR Sbjct: 2 ATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALLR 61 Query: 330 ML 335 L Sbjct: 62 RL 63
>CDK4_HUMAN (P11802) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 52.8 bits (125), Expect = 2e-07 Identities = 28/62 (45%), Positives = 38/62 (61%), Gaps = 3/62 (4%) Frame = +3 Query: 159 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPE---DDEGVPPTALREVSLLR 329 A YE + ++G G YG VYKAR+ +G VALK R+P G+P + +REV+LLR Sbjct: 2 ATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLR 61 Query: 330 ML 335 L Sbjct: 62 RL 63
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 52.8 bits (125), Expect = 2e-07 Identities = 27/56 (48%), Positives = 36/56 (64%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 MD Y L ++GEG +G V+KA+ TG IVALKK L ++G P ALRE+ L+ Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQ 56
>AL2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) Length = 384 Score = 52.4 bits (124), Expect = 3e-07 Identities = 29/59 (49%), Positives = 38/59 (64%) Frame = +3 Query: 159 AMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 A Y LEK+GEG+Y VYK + G++VALK + +EGVP TA+RE SLL+ L Sbjct: 48 AASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISM-NAEEGVPFTAIREASLLKGL 105
>CRK1_SCHPO (Q12126) Serine/threonine-protein kinase crk1 (EC 2.7.11.23)| (Mitotic catastrophe suppressor 6) Length = 335 Score = 51.6 bits (122), Expect = 5e-07 Identities = 25/53 (47%), Positives = 35/53 (66%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 Y K KVGEGTY V+ R+K T R VA+KK ++ + +G+ +ALRE+ LR Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLR 63
>BUR1_DEBHA (Q6BV06) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 608 Score = 50.8 bits (120), Expect = 8e-07 Identities = 25/56 (44%), Positives = 38/56 (67%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 YE ++K+G+GT+G V KAR T +VALK+ EG P TA+RE+++L+ L+ Sbjct: 39 YEIIQKLGQGTFGVVQKARNIKTKELVALKQLINHSAKEGFPITAMREITILKKLN 94
>CDK7_DICDI (P54685) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (MO15 homolog) Length = 362 Score = 50.4 bits (119), Expect = 1e-06 Identities = 28/62 (45%), Positives = 40/62 (64%), Gaps = 4/62 (6%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTR----LPEDDEGVPPTALREVSLLR 329 MD Y +GEGTYG V +A KATG+IVA+KK R + D+G+ +A+RE+ +L+ Sbjct: 1 MDKYNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQ 60 Query: 330 ML 335 L Sbjct: 61 EL 62
>M4K1_HUMAN (Q92918) Mitogen-activated protein kinase kinase kinase kinase 1| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) Length = 833 Score = 49.7 bits (117), Expect = 2e-06 Identities = 23/55 (41%), Positives = 39/55 (70%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 D Y+ L+++G GTYG+V+KAR+K +G +VALK ++ DD+ T +E+ +L+ Sbjct: 15 DHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDD--VSTLQKEILILK 67
>CDKL3_MOUSE (Q8BLF2) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 595 Score = 49.3 bits (116), Expect = 2e-06 Identities = 26/56 (46%), Positives = 36/56 (64%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M++YE L KVGEG+YG V K + K TGRIVA+ K + ++ V A RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKDTGRIVAI-KIFYEKPEKSVNKIATREIKFLK 55
>CDKL3_RAT (Q9JM01) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIATRE) Length = 593 Score = 49.3 bits (116), Expect = 2e-06 Identities = 26/56 (46%), Positives = 36/56 (64%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M++YE L KVGEG+YG V K + K TGRIVA+ K + ++ V A RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKDTGRIVAI-KIFYEKPEKSVNKIATREIKFLK 55
>CDKL3_HUMAN (Q8IVW4) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIAMRE) Length = 592 Score = 48.9 bits (115), Expect = 3e-06 Identities = 25/56 (44%), Positives = 36/56 (64%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M++YE L KVGEG+YG V K + K TG+IVA+ K ++ V A+RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLK 55
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 48.9 bits (115), Expect = 3e-06 Identities = 25/56 (44%), Positives = 36/56 (64%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 M++YE L KVGEG+YG V K + K TG+IVA+ K ++ V A+RE+ L+ Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLK 55
>STK4_HUMAN (Q13043) Serine/threonine-protein kinase 4 (EC 2.7.11.1)| (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 48.5 bits (114), Expect = 4e-06 Identities = 22/55 (40%), Positives = 40/55 (72%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 ++++ LEK+GEG+YG VYKA K TG+IVA+K+ + D + + ++E+S+++ Sbjct: 28 EVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEI----IKEISIMQ 78
>BUR1_CANGA (Q6FQ83) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 667 Score = 48.1 bits (113), Expect = 5e-06 Identities = 22/56 (39%), Positives = 40/56 (71%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 Y++ EK+G+GT+G+VYK T R VA+K+ + ++++ P TA RE+++L+ L+ Sbjct: 60 YKEEEKLGQGTFGEVYKGLHLQTQRKVAMKRIIVNQENDLFPITAQREITILKRLN 115
>BUR1_ASHGO (Q75D46) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 753 Score = 47.8 bits (112), Expect = 7e-06 Identities = 22/56 (39%), Positives = 40/56 (71%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 Y++ +K+G+GT+G+VY+ AT R VA+KK + +++ P TA RE+++L+ L+ Sbjct: 56 YKEEKKLGQGTFGEVYRGVHLATQRQVAMKKILVKTENDLFPITAQREITILKRLN 111
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 47.8 bits (112), Expect = 7e-06 Identities = 23/53 (43%), Positives = 35/53 (66%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 Y K +KVGEGTY VY + +TGR +A+K+ + E +G+ +A+REV L+ Sbjct: 7 YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQ 59
>BUR1_YEAST (P23293) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) (Suppressor of GPA1-Vall50 mutation protein 1) (Bypass UAS requirement protein 1) Length = 657 Score = 46.2 bits (108), Expect = 2e-05 Identities = 23/56 (41%), Positives = 37/56 (66%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 Y + EK+G+GT+G+VYK T R VA+KK + + + P TA RE+++L+ L+ Sbjct: 60 YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLN 115
>M4K1_MOUSE (P70218) Mitogen-activated protein kinase kinase kinase kinase 1| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK) Length = 827 Score = 45.4 bits (106), Expect = 3e-05 Identities = 21/53 (39%), Positives = 37/53 (69%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 Y+ L+++G GTYG+V+KAR+K + +VALK ++ DD+ T +E+ +L+ Sbjct: 17 YDLLQRLGGGTYGEVFKARDKVSKDLVALKMVKMEPDDD--VATLQKEILMLK 67
>STK3_HUMAN (Q13188) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1) Length = 491 Score = 45.1 bits (105), Expect = 4e-05 Identities = 19/55 (34%), Positives = 40/55 (72%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 ++++ LEK+GEG+YG V+KA K +G++VA+K+ + D + + ++E+S+++ Sbjct: 25 EVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEI----IKEISIMQ 75
>STK3_MOUSE (Q9JI10) Serine/threonine-protein kinase 3 (EC 2.7.11.1)| (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) Length = 497 Score = 45.1 bits (105), Expect = 4e-05 Identities = 19/55 (34%), Positives = 40/55 (72%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 ++++ LEK+GEG+YG V+KA K +G++VA+K+ + D + + ++E+S+++ Sbjct: 25 EVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEI----IKEISIMQ 75
>MINK1_HUMAN (Q8N4C8) Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated| protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK) Length = 1332 Score = 44.7 bits (104), Expect = 6e-05 Identities = 22/57 (38%), Positives = 36/57 (63%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 ++E +E VG GTYG+VYK R TG++ A+K + ED+E +E+++L+ S Sbjct: 24 IFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEE---EEIKQEINMLKKYS 77
>BUR1_KLULA (Q6CRA9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 645 Score = 44.7 bits (104), Expect = 6e-05 Identities = 20/56 (35%), Positives = 37/56 (66%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 Y + EK+G+GT+G+V+K T R VA+K+ + + + P TA RE+++L+ ++ Sbjct: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMN 110
>MINK1_MOUSE (Q9JM52) Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated| protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK) Length = 1308 Score = 44.7 bits (104), Expect = 6e-05 Identities = 22/57 (38%), Positives = 36/57 (63%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 ++E +E VG GTYG+VYK R TG++ A+K + ED+E +E+++L+ S Sbjct: 24 IFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEE---EEIKQEINMLKKYS 77
>M4K4_HUMAN (O95819) Mitogen-activated protein kinase kinase kinase kinase 4| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase) Length = 1239 Score = 44.3 bits (103), Expect = 8e-05 Identities = 19/40 (47%), Positives = 28/40 (70%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDE 287 ++E +E VG GTYG+VYK R TG++ A+K + ED+E Sbjct: 24 IFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEE 63
>M4K2_MOUSE (Q61161) Mitogen-activated protein kinase kinase kinase kinase 2| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein) Length = 821 Score = 44.3 bits (103), Expect = 8e-05 Identities = 22/55 (40%), Positives = 35/55 (63%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 D +E L++VG GTYG VYKAR+ T + A+K +L D+ + +E+++LR Sbjct: 14 DRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDD--ISSLQQEITILR 66
>M4K2_HUMAN (Q12851) Mitogen-activated protein kinase kinase kinase kinase 2| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-pro Length = 819 Score = 44.3 bits (103), Expect = 8e-05 Identities = 22/55 (40%), Positives = 35/55 (63%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 D +E L++VG GTYG VYKAR+ T + A+K +L D+ + +E+++LR Sbjct: 13 DRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDD--ISSLQQEITILR 65
>SRK1_SCHPO (O94547) Serine/threonine-protein kinase srk1 (EC 2.7.11.1)| (Sty1-regulated kinase 1) Length = 580 Score = 43.5 bits (101), Expect = 1e-04 Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 11/107 (10%) Frame = +3 Query: 42 RQPTREREREKARICAMA-TLQHQNQGAAAPMXXXXXXLRAMDLYEKLEKVGEGTYGKVY 218 +QPT E+E +KA +A + ++ G P+ + ++ Y L+K+G+G + VY Sbjct: 86 KQPTNEKEYDKAIEALVAKAIVEEHSGQQFPVY------KGLEQYTLLQKMGDGAFSNVY 139 Query: 219 KAREKATGRIVALK---------KTRLPEDDEGVPP-TALREVSLLR 329 KA TG VA+K R P +GV L+EV ++R Sbjct: 140 KAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKEVQIMR 186
>M4K5_HUMAN (Q9Y4K4) Mitogen-activated protein kinase kinase kinase kinase 5| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) (Kinase homologous to SPS1/STE20) (KHS) Length = 846 Score = 42.7 bits (99), Expect = 2e-04 Identities = 21/39 (53%), Positives = 27/39 (69%), Gaps = 1/39 (2%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL-PEDD 284 YE +++VG GTYG VYKAR TG + A+K +L P DD Sbjct: 20 YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDD 58
>M4K5_MOUSE (Q8BPM2) Mitogen-activated protein kinase kinase kinase kinase 5| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) Length = 847 Score = 42.7 bits (99), Expect = 2e-04 Identities = 21/39 (53%), Positives = 27/39 (69%), Gaps = 1/39 (2%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL-PEDD 284 YE +++VG GTYG VYKAR TG + A+K +L P DD Sbjct: 20 YELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDD 58
>MIG15_CAEEL (Q23356) Serine/threonine-protein kinase mig-15 (EC 2.7.11.1)| (Abnormal cell migration protein 15) Length = 1096 Score = 42.7 bits (99), Expect = 2e-04 Identities = 18/40 (45%), Positives = 27/40 (67%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDE 287 ++E +E VG GTYG+VYK R T ++ A+K + ED+E Sbjct: 20 IFELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEE 59
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 42.4 bits (98), Expect = 3e-04 Identities = 21/61 (34%), Positives = 35/61 (57%) Frame = +3 Query: 153 LRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 332 L +D ++ EK+G G + +VYK R + +G+++ LK +LP + LREV L+ Sbjct: 46 LARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRS----NTLREVQLMNR 101 Query: 333 L 335 L Sbjct: 102 L 102
>STK36_MOUSE (Q69ZM6) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1268 Score = 42.4 bits (98), Expect = 3e-04 Identities = 22/58 (37%), Positives = 34/58 (58%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y LE +GEG++G+VYK R+K + ++VALK E RE+ ++R L Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGL 58
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 42.4 bits (98), Expect = 3e-04 Identities = 21/61 (34%), Positives = 35/61 (57%) Frame = +3 Query: 153 LRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 332 L +D ++ EK+G G + +VYK R + +G+++ LK +LP + LREV L+ Sbjct: 46 LARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRS----NTLREVQLMNR 101 Query: 333 L 335 L Sbjct: 102 L 102
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 42.0 bits (97), Expect = 4e-04 Identities = 23/57 (40%), Positives = 35/57 (61%), Gaps = 1/57 (1%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPE-DDEGVPPTALREVSLLRMLS 338 YE E +G+GTYGKV +A E+ +GR+VA+K R + DE RE+ ++ L+ Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLN 111
>TNIK_MOUSE (P83510) Traf2 and NCK-interacting kinase (EC 2.7.11.1) (Fragments)| Length = 916 Score = 42.0 bits (97), Expect = 4e-04 Identities = 21/57 (36%), Positives = 35/57 (61%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 ++E +E VG GTYG+VYK R TG++ A+K + D+E +E+++L+ S Sbjct: 24 IFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEE---EEIKQEINMLKKYS 77
>TNIK_HUMAN (Q9UKE5) TRAF2 and NCK-interacting kinase (EC 2.7.11.1)| Length = 1360 Score = 42.0 bits (97), Expect = 4e-04 Identities = 21/57 (36%), Positives = 35/57 (61%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 ++E +E VG GTYG+VYK R TG++ A+K + D+E +E+++L+ S Sbjct: 24 IFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEE---EEIKQEINMLKKYS 77
>E2AK1_HUMAN (Q9BQI3) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 630 Score = 42.0 bits (97), Expect = 4e-04 Identities = 22/57 (38%), Positives = 34/57 (59%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R ++ +E+L +G+G YG+VYK R K G+ A+KK + + V LREV +L Sbjct: 162 RYLNEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVL 218
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 42.0 bits (97), Expect = 4e-04 Identities = 22/58 (37%), Positives = 33/58 (56%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y LE +GEG++G+VYK R K + ++VALK E RE+ ++R L Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGL 58
>STK36_HUMAN (Q9NRP7) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 42.0 bits (97), Expect = 4e-04 Identities = 22/58 (37%), Positives = 33/58 (56%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 M+ Y LE +GEG++G+VYK R K + ++VALK E RE+ ++R L Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGL 58
>CDK8_DROME (Q9VT57) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (DmCdk8) Length = 454 Score = 41.6 bits (96), Expect = 5e-04 Identities = 26/52 (50%), Positives = 33/52 (63%), Gaps = 2/52 (3%) Frame = +3 Query: 186 KVGEGTYGKVYKAREKAT--GRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 KVG GTYG VYKA+ K T G+ ALK+ D G+ +A RE++LLR L Sbjct: 26 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLREL 73
>E2AK1_RABIT (P33279) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 626 Score = 41.6 bits (96), Expect = 5e-04 Identities = 26/87 (29%), Positives = 42/87 (48%) Frame = +3 Query: 66 REKARICAMATLQHQNQGAAAPMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGR 245 RE+ R A H + + + R ++ +E+L +G+G YG+VYK R K G+ Sbjct: 135 RERVRQDPCADNSHIQKIRSREVALEAQTSRYLNEFEELSILGKGGYGRVYKVRNKLDGQ 194 Query: 246 IVALKKTRLPEDDEGVPPTALREVSLL 326 A+KK + + LREV +L Sbjct: 195 YYAIKKILIKGATKTDCMKVLREVKVL 221
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 41.2 bits (95), Expect = 6e-04 Identities = 18/33 (54%), Positives = 25/33 (75%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTR 269 YE E +G+GTYGKV +A E+ +GR+VA+K R Sbjct: 56 YELQETLGKGTYGKVKRATERFSGRVVAIKSIR 88
>M4K3_MOUSE (Q99JP0) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) (Fragments) Length = 681 Score = 40.8 bits (94), Expect = 8e-04 Identities = 19/42 (45%), Positives = 28/42 (66%), Gaps = 1/42 (2%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL-PEDDEGV 293 +E ++++G GTYG VYKAR TG + A+K +L P +D V Sbjct: 16 FELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAV 57
>LIMK1_DROME (Q8IR79) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (dLIMK)| Length = 1257 Score = 40.8 bits (94), Expect = 8e-04 Identities = 20/51 (39%), Positives = 33/51 (64%) Frame = +3 Query: 183 EKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 EK+GEG +GKV+K + +G ++ LK+ L DE ++EV++LR+L Sbjct: 405 EKLGEGFFGKVFKVTHRQSGEVMVLKE--LHRADEEAQRNFIKEVAVLRLL 453
>M4K3_RAT (Q924I2) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) (Fragment) Length = 862 Score = 40.8 bits (94), Expect = 8e-04 Identities = 19/42 (45%), Positives = 28/42 (66%), Gaps = 1/42 (2%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL-PEDDEGV 293 +E ++++G GTYG VYKAR TG + A+K +L P +D V Sbjct: 5 FELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAV 46
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 40.8 bits (94), Expect = 8e-04 Identities = 21/61 (34%), Positives = 34/61 (55%) Frame = +3 Query: 153 LRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRM 332 L +D + EK+G G + +VYK R + +G+++ LK +LP + LREV L+ Sbjct: 51 LARVDDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSN----RGNTLREVQLMNR 106 Query: 333 L 335 L Sbjct: 107 L 107
>MK12_BRARE (O42376) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Stress-activated protein kinase 3) Length = 363 Score = 40.8 bits (94), Expect = 8e-04 Identities = 22/55 (40%), Positives = 31/55 (56%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 D Y+ L++VG G YG V A ++ TG VA+KK P + A RE+ LL+ Sbjct: 23 DRYKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPFQSDLFAKRAYRELRLLK 77
>M4K3_HUMAN (Q8IVH8) Mitogen-activated protein kinase kinase kinase kinase 3| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) (Germinal center kinase-related protein kinase) (GLK) Length = 894 Score = 40.8 bits (94), Expect = 8e-04 Identities = 19/42 (45%), Positives = 28/42 (66%), Gaps = 1/42 (2%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL-PEDDEGV 293 +E ++++G GTYG VYKAR TG + A+K +L P +D V Sbjct: 16 FELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAV 57
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 40.4 bits (93), Expect = 0.001 Identities = 22/54 (40%), Positives = 29/54 (53%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 +Y+ L+ VG G YG V A + TG VA+KK P E A RE+ LL+ Sbjct: 26 VYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLK 79
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 40.4 bits (93), Expect = 0.001 Identities = 22/54 (40%), Positives = 29/54 (53%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 +Y+ L+ VG G YG V A + TG VA+KK P E A RE+ LL+ Sbjct: 26 VYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLK 79
>PMYT1_HUMAN (Q99640) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 499 Score = 40.0 bits (92), Expect = 0.001 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 9/100 (9%) Frame = +3 Query: 3 LPQPPPHQ----ITRLARQPTR-----EREREKARICAMATLQHQNQGAAAPMXXXXXXL 155 LP PPP + I+RL T + R R A TLQ + P Sbjct: 51 LPPPPPAKGSIPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQS- 109 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLP 275 +++L ++G G+YG+V+K R K GR+ A+K++ P Sbjct: 110 -----FQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSP 144
>STK24_MOUSE (Q99KH8) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| Length = 431 Score = 40.0 bits (92), Expect = 0.001 Identities = 16/43 (37%), Positives = 31/43 (72%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGV 293 +L+ KLEK+G+G++G+V+K + T ++VA+K L E ++ + Sbjct: 22 ELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEI 64
>STK24_HUMAN (Q9Y6E0) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 40.0 bits (92), Expect = 0.001 Identities = 16/43 (37%), Positives = 31/43 (72%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGV 293 +L+ KLEK+G+G++G+V+K + T ++VA+K L E ++ + Sbjct: 34 ELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEI 76
>ERK1_CANAL (P28869) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) (MAPK 1) Length = 417 Score = 40.0 bits (92), Expect = 0.001 Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 11/114 (9%) Frame = +3 Query: 21 HQITRLARQPTREREREKARICAMATLQHQNQGAAAPMXXXXXX-----------LRAMD 167 HQ+ + +Q +++ + A+ A A Q Q Q AAA D Sbjct: 8 HQLQQQHQQQMLQQQAQ-AQAQAQAQAQQQQQAAAAAAAANAAATTSSSSPRQVSFNVSD 66 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 Y+ LE VGEG YG V A K + + VA+KK P + + LRE+ LL+ Sbjct: 67 HYQILEIVGEGAYGIVCSAIHKPSQQKVAIKKIE-PFERSMLCLRTLRELKLLK 119
>KIC1_YEAST (P38692) Serine/threonine-protein kinase KIC1 (EC 2.7.11.1) (Kinase| that interacts with CDC31) (N-rich kinase 1) Length = 1080 Score = 40.0 bits (92), Expect = 0.001 Identities = 21/58 (36%), Positives = 30/58 (51%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 341 L+++ E +G G +G VYK TGR+ A+K L D + V RE+ L L Q Sbjct: 22 LFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQ-REIQFLASLKQ 78
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 39.7 bits (91), Expect = 0.002 Identities = 22/55 (40%), Positives = 30/55 (54%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 D YE +E +G G YG V AR + TG+ VA+KK D LRE+ +L+ Sbjct: 52 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILK 106
>MK07_MOUSE (Q9WVS8) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase) Length = 806 Score = 39.7 bits (91), Expect = 0.002 Identities = 22/55 (40%), Positives = 30/55 (54%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 D YE +E +G G YG V AR + TG+ VA+KK D LRE+ +L+ Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILK 107
>E2AK1_MOUSE (Q9Z2R9) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 619 Score = 39.3 bits (90), Expect = 0.002 Identities = 21/57 (36%), Positives = 33/57 (57%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R ++ +E+L +G+G YG+VYK R K G+ A+KK + + LREV +L Sbjct: 162 RYLNEFEELAILGKGGYGRVYKVRNKLDGQHYAIKKILIKSATKTDCMKVLREVKVL 218
>STK10_MOUSE (O55098) Serine/threonine-protein kinase 10 (EC 2.7.11.1)| (Lymphocyte-oriented kinase) Length = 966 Score = 39.3 bits (90), Expect = 0.002 Identities = 16/41 (39%), Positives = 27/41 (65%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDE 287 D++E + ++G+G +GKVYKA+ K TG + A K ++E Sbjct: 34 DVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEE 74
>E2AK1_RAT (Q63185) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2- Length = 620 Score = 39.3 bits (90), Expect = 0.002 Identities = 21/57 (36%), Positives = 33/57 (57%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R ++ +E+L +G+G YG+VYK R K G+ A+KK + + LREV +L Sbjct: 162 RYLNEFEELAILGKGGYGRVYKVRNKLDGQHYAIKKILIKSATKTDCMKVLREVKVL 218
>GCN2_ARATH (Q9LX30) Probable serine/threonine-protein kinase GCN2 (EC| 2.7.11.1) Length = 1241 Score = 38.9 bits (89), Expect = 0.003 Identities = 21/60 (35%), Positives = 35/60 (58%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 R ++ +E+L+ +G+G +G V + K GR A+KK RL + + V +REV+ L L Sbjct: 420 RYLNDFEELKPLGQGGFGHVVLCKNKLDGRQYAVKKIRLKDKEIPVNSRIVREVATLSRL 479
>WEE1_RAT (Q63802) Wee1-like protein kinase (EC 2.7.10.2)| Length = 646 Score = 38.9 bits (89), Expect = 0.003 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 341 + +LEK+G G +G V+K ++ G I A+K+++ P ALREV +L Q Sbjct: 298 FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQ 354
>WEE1_MOUSE (P47810) Wee1-like protein kinase (EC 2.7.10.2)| Length = 646 Score = 38.9 bits (89), Expect = 0.003 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 341 + +LEK+G G +G V+K ++ G I A+K+++ P ALREV +L Q Sbjct: 298 FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQ 354
>WEE1_HUMAN (P30291) Wee1-like protein kinase (EC 2.7.10.2) (WEE1hu)| Length = 646 Score = 38.9 bits (89), Expect = 0.003 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 341 + +LEK+G G +G V+K ++ G I A+K+++ P ALREV +L Q Sbjct: 299 FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQ 355
>MK14A_DROME (O62618) Mitogen-activated protein kinase 14A (EC 2.7.11.24) (MAP| kinase p38a) (p38 MAPK) (Dp38) (D-p38a) Length = 366 Score = 38.9 bits (89), Expect = 0.003 Identities = 21/55 (38%), Positives = 29/55 (52%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 D+Y+ L+ VG G YG+V KA + T VA+KK P RE+ LL+ Sbjct: 23 DIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLK 77
>MYO3B_HUMAN (Q8WXR4) Myosin IIIB (EC 2.7.11.1)| Length = 1341 Score = 38.9 bits (89), Expect = 0.003 Identities = 16/32 (50%), Positives = 22/32 (68%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALK 260 D +E +E +G+GTYGKVYK K G + A+K Sbjct: 25 DTWEIIETIGKGTYGKVYKVTNKRDGSLAAVK 56
>MST4_MOUSE (Q99JT2) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) Length = 416 Score = 38.5 bits (88), Expect = 0.004 Identities = 15/43 (34%), Positives = 31/43 (72%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGV 293 +L+ KLE++G+G++G+V+K + T ++VA+K L E ++ + Sbjct: 22 ELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEI 64
>MST4_HUMAN (Q9P289) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase) Length = 416 Score = 38.5 bits (88), Expect = 0.004 Identities = 15/43 (34%), Positives = 31/43 (72%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGV 293 +L+ KLE++G+G++G+V+K + T ++VA+K L E ++ + Sbjct: 22 ELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEI 64
>MK15_RAT (Q9Z2A6) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 547 Score = 38.5 bits (88), Expect = 0.004 Identities = 19/48 (39%), Positives = 29/48 (60%) Frame = +3 Query: 186 KVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 ++G+G YG V+KA ++ TG +VA+KK D+ RE+ LLR Sbjct: 19 RLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIMLLR 66
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 38.5 bits (88), Expect = 0.004 Identities = 21/56 (37%), Positives = 33/56 (58%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 Y + +G G+YG VYKA K T ++VA+K+ D+E + E+SLL+ L+ Sbjct: 25 YHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEE--LNDIMAEISLLKNLN 78
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 38.5 bits (88), Expect = 0.004 Identities = 19/52 (36%), Positives = 32/52 (61%) Frame = +3 Query: 183 EKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLS 338 EK+G G + +V+K R +A+G+++ALK L + + L+EV L+ LS Sbjct: 62 EKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANM----LKEVQLMNRLS 109
>MK12_HUMAN (P53778) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 38.5 bits (88), Expect = 0.004 Identities = 22/54 (40%), Positives = 28/54 (51%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 +Y L+ VG G YG V A + TG VA+KK P E A RE+ LL+ Sbjct: 26 VYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLK 79
>CD2L6_MOUSE (Q8BWD8) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) Length = 501 Score = 38.5 bits (88), Expect = 0.004 Identities = 28/63 (44%), Positives = 36/63 (57%), Gaps = 3/63 (4%) Frame = +3 Query: 156 RAMDLYEKLE-KVGEGTYGKVYKAREK--ATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R DL+E KVG GTYG VYKAR K + ALK+ + G+ +A RE++LL Sbjct: 15 RVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALL 70 Query: 327 RML 335 R L Sbjct: 71 REL 73
>WIS1_SCHPO (P33886) Protein kinase wis1 (EC 2.7.12.2) (Protein kinase sty2)| Length = 605 Score = 38.5 bits (88), Expect = 0.004 Identities = 18/32 (56%), Positives = 24/32 (75%) Frame = +3 Query: 177 KLEKVGEGTYGKVYKAREKATGRIVALKKTRL 272 KLE++G+G YG VYKA + TG +ALK+ RL Sbjct: 322 KLEELGKGNYGVVYKALHQPTGVTMALKEIRL 353
>CD2L6_HUMAN (Q9BWU1) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11) Length = 502 Score = 38.5 bits (88), Expect = 0.004 Identities = 28/63 (44%), Positives = 36/63 (57%), Gaps = 3/63 (4%) Frame = +3 Query: 156 RAMDLYEKLE-KVGEGTYGKVYKAREK--ATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R DL+E KVG GTYG VYKAR K + ALK+ + G+ +A RE++LL Sbjct: 15 RVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALL 70 Query: 327 RML 335 R L Sbjct: 71 REL 73
>STK25_MOUSE (Q9Z2W1) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 38.1 bits (87), Expect = 0.005 Identities = 15/43 (34%), Positives = 30/43 (69%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGV 293 +L+ KL+++G+G++G+VYK + T +VA+K L E ++ + Sbjct: 18 ELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEI 60
>STK25_HUMAN (O00506) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 38.1 bits (87), Expect = 0.005 Identities = 15/43 (34%), Positives = 30/43 (69%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGV 293 +L+ KL+++G+G++G+VYK + T +VA+K L E ++ + Sbjct: 18 ELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEI 60
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 38.1 bits (87), Expect = 0.005 Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 4/59 (6%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALK----KTRLPEDDEGVPPTALREVSLLRML 335 Y+ L+ +GEG++GKV A+ TG+ VALK KT D +G RE+S LR+L Sbjct: 53 YQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQG---RVEREISYLRLL 108
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 38.1 bits (87), Expect = 0.005 Identities = 18/36 (50%), Positives = 26/36 (72%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTR 269 M+ ++ L+ +G+GT+GKV REKATGR A+K R Sbjct: 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILR 184
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 38.1 bits (87), Expect = 0.005 Identities = 18/36 (50%), Positives = 26/36 (72%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTR 269 M+ ++ L+ +G+GT+GKV REKATGR A+K R Sbjct: 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILR 184
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 38.1 bits (87), Expect = 0.005 Identities = 18/36 (50%), Positives = 26/36 (72%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTR 269 M+ ++ L+ +G+GT+GKV REKATGR A+K R Sbjct: 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILR 184
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 38.1 bits (87), Expect = 0.005 Identities = 17/33 (51%), Positives = 25/33 (75%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALK 260 M+ +E L+ +G+GT+GKV +EKATGR A+K Sbjct: 148 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMK 180
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 38.1 bits (87), Expect = 0.005 Identities = 17/33 (51%), Positives = 25/33 (75%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALK 260 M+ +E L+ +G+GT+GKV +EKATGR A+K Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMK 179
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 38.1 bits (87), Expect = 0.005 Identities = 17/33 (51%), Positives = 25/33 (75%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALK 260 M+ +E L+ +G+GT+GKV +EKATGR A+K Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMK 179
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 38.1 bits (87), Expect = 0.005 Identities = 17/33 (51%), Positives = 25/33 (75%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALK 260 M+ +E L+ +G+GT+GKV +EKATGR A+K Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMK 179
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 38.1 bits (87), Expect = 0.005 Identities = 17/33 (51%), Positives = 25/33 (75%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALK 260 M+ +E L+ +G+GT+GKV +EKATGR A+K Sbjct: 168 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMK 200
>PMYT1_MOUSE (Q9ESG9) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 490 Score = 38.1 bits (87), Expect = 0.005 Identities = 14/35 (40%), Positives = 25/35 (71%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLP 275 +++L ++G G+YG+V+K R K GR+ A+K+ P Sbjct: 101 FQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRYMSP 135
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 38.1 bits (87), Expect = 0.005 Identities = 18/36 (50%), Positives = 26/36 (72%) Frame = +3 Query: 162 MDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTR 269 M+ ++ L+ +G+GT+GKV REKATGR A+K R Sbjct: 154 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILR 189
>E2AK1_SCHPO (O13889) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor 1) Length = 704 Score = 37.7 bits (86), Expect = 0.007 Identities = 19/34 (55%), Positives = 23/34 (67%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL 272 +E+LE +G+G YG VYKAR K G ALKK L Sbjct: 224 FEELELLGKGGYGSVYKARNKFDGVEYALKKIPL 257
>NAK1_SCHPO (O75011) Serine/threonine-protein kinase nak1 (EC 2.7.11.1) (N-rich| kinase 1) Length = 652 Score = 37.7 bits (86), Expect = 0.007 Identities = 23/57 (40%), Positives = 31/57 (54%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRMLSQ 341 Y KLE VG G+YG VY+ T VA+K L D++ V +EV++L L Q Sbjct: 10 YTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQ-KEVAVLSELKQ 65
>ATG1_NEUCR (Q7RX99) Serine/threonine-protein kinase atg-1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 932 Score = 37.7 bits (86), Expect = 0.007 Identities = 16/51 (31%), Positives = 30/51 (58%) Frame = +3 Query: 183 EKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 +++G+G++ KVY R K TG +VA+K L ++ + E+ +L+ L Sbjct: 28 QEIGKGSFAKVYLGRHKVTGALVAVKSVELARLNKKLKENLYGEIQILKTL 78
>PDK1B_XENLA (Q6NU98) Serine/threonine-protein kinase pdik1l-B (EC 2.7.11.1)| Length = 339 Score = 37.7 bits (86), Expect = 0.007 Identities = 23/50 (46%), Positives = 32/50 (64%), Gaps = 2/50 (4%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTR--LPEDDEGVPPTALRE 314 Y+ + +VG G+YG VY+A + TG+ VA+KK R PE+ E ALRE Sbjct: 8 YDLIREVGRGSYGLVYEALVRRTGQRVAVKKIRCQAPENVE----LALRE 53
>M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1) Length = 1607 Score = 37.7 bits (86), Expect = 0.007 Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 1/46 (2%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL-PEDDEGVPPTA 305 +++ K+GEG YGKVY TG ++A+K+ R P D + + TA Sbjct: 1342 WQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETA 1387
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 37.7 bits (86), Expect = 0.007 Identities = 26/75 (34%), Positives = 40/75 (53%), Gaps = 3/75 (4%) Frame = +3 Query: 108 QNQGAAAPMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALK---KTRLPE 278 +N+GA A +D +E +G+G +G VY AREK + IVALK K+++ Sbjct: 59 ENKGATALQGSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQI-- 116 Query: 279 DDEGVPPTALREVSL 323 + EGV RE+ + Sbjct: 117 EKEGVEHQLRREIEI 131
>M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Length = 1597 Score = 37.7 bits (86), Expect = 0.007 Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 1/46 (2%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTRL-PEDDEGVPPTA 305 +++ K+GEG YGKVY TG ++A+K+ R P D + + TA Sbjct: 1332 WQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETA 1377
>STK10_HUMAN (O94804) Serine/threonine-protein kinase 10 (EC 2.7.11.1)| (Lymphocyte-oriented kinase) Length = 968 Score = 37.7 bits (86), Expect = 0.007 Identities = 15/41 (36%), Positives = 27/41 (65%) Frame = +3 Query: 165 DLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDE 287 +++E + ++G+G +GKVYKA+ K TG + A K ++E Sbjct: 34 EVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEE 74
>CDK8_HUMAN (P49336) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (Protein kinase K35) Length = 464 Score = 37.7 bits (86), Expect = 0.007 Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 3/63 (4%) Frame = +3 Query: 156 RAMDLYEKLE-KVGEGTYGKVYKAREK--ATGRIVALKKTRLPEDDEGVPPTALREVSLL 326 R DL+E KVG GTYG VYKA+ K + ALK+ + G+ +A RE++LL Sbjct: 15 RVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALL 70 Query: 327 RML 335 R L Sbjct: 71 REL 73
>NEK2_HUMAN (P51955) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21) Length = 445 Score = 37.4 bits (85), Expect = 0.009 Identities = 23/60 (38%), Positives = 32/60 (53%) Frame = +3 Query: 156 RAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLRML 335 RA D YE L +G G+YG+ K R K+ G+I+ K+ E + EV+LLR L Sbjct: 4 RAED-YEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLREL 62
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 37.4 bits (85), Expect = 0.009 Identities = 24/59 (40%), Positives = 35/59 (59%), Gaps = 4/59 (6%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALK----KTRLPEDDEGVPPTALREVSLLRML 335 Y+ ++ +GEG++GKV A+ TG+ VALK KT D +G RE+S LR+L Sbjct: 52 YQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQG---RVEREISYLRLL 107
>HIPPO_DROME (Q8T0S6) Serine/threonine-protein kinase hippo (EC 2.7.11.1)| Length = 669 Score = 37.4 bits (85), Expect = 0.009 Identities = 18/54 (33%), Positives = 34/54 (62%) Frame = +3 Query: 168 LYEKLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEGVPPTALREVSLLR 329 +++ + K+GEG+YG VYKA K + IVA+K + D + ++E+S+++ Sbjct: 41 VFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEI----IKEISIMQ 90
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 37.4 bits (85), Expect = 0.009 Identities = 16/38 (42%), Positives = 24/38 (63%) Frame = +3 Query: 177 KLEKVGEGTYGKVYKAREKATGRIVALKKTRLPEDDEG 290 K E +G GTYGKV+ A TG ++A+K+ +P+ G Sbjct: 827 KGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTING 864
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 37.4 bits (85), Expect = 0.009 Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 3/77 (3%) Frame = +3 Query: 102 QHQNQGAAAPMXXXXXXLRAMDLYEKLEKVGEGTYGKVYKAREKATGRIVALK---KTRL 272 ++++QG+ A +D +E +G+G +G VY AREK + IVALK K+++ Sbjct: 59 ENKSQGSTASQGSQNKQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQI 118 Query: 273 PEDDEGVPPTALREVSL 323 + EGV RE+ + Sbjct: 119 --EKEGVEHQLRREIEI 133
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 37.4 bits (85), Expect = 0.009 Identities = 19/33 (57%), Positives = 22/33 (66%) Frame = +3 Query: 171 YEKLEKVGEGTYGKVYKAREKATGRIVALKKTR 269 YE LEK+GEG KVYKA+ RIVA+K R Sbjct: 10 YEILEKIGEGGMAKVYKAKCHLLNRIVAIKILR 42 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.310 0.130 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,876,230 Number of Sequences: 219361 Number of extensions: 539929 Number of successful extensions: 3820 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 3331 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3747 length of database: 80,573,946 effective HSP length: 89 effective length of database: 61,050,817 effective search space used: 1465219608 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits)
