ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bast42f11 |
|---|---|
| Clone Library Name | barley_pub |
>KPK1_PHAVU (P15792) Protein kinase PVPK-1 (EC 2.7.11.1)| Length = 609 Score = 88.2 bits (217), Expect = 7e-18 Identities = 53/139 (38%), Positives = 73/139 (52%), Gaps = 3/139 (2%) Frame = +1 Query: 19 IDLPSARAARVLGRGAMGTVFLVAADA---EYALKVFDRRSHAPGXXXXXXXXXXWEVSV 189 +++ R + LG G +G+V+L +A+KV ++ A E + Sbjct: 224 LEMRHFRLLKKLGCGDIGSVYLAELSGTRTSFAMKVMNKTELANRKKLLRAQT---EREI 280 Query: 190 LSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVS 369 L L HP LP+L ET M +C GGDL+ LR+ QP + FS AVRFY AE++ Sbjct: 281 LQSLDHPFLPTLYTHFETEIFSCLVMEFCPGGDLHALRQRQPGKYFSEHAVRFYVAEVLL 340 Query: 370 ALADLHAAGIAYRDLKPEN 426 +L LH GI YRDLKPEN Sbjct: 341 SLEYLHMLGIIYRDLKPEN 359
>G11A_ORYSA (P47997) Protein kinase G11A (EC 2.7.11.1)| Length = 589 Score = 85.1 bits (209), Expect = 6e-17 Identities = 52/139 (37%), Positives = 72/139 (51%), Gaps = 3/139 (2%) Frame = +1 Query: 19 IDLPSARAARVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSV 189 + L + + LG G +G+V+L + +A+KV D+ S A E + Sbjct: 190 LGLSHFKLLKKLGCGDIGSVYLSELSGTKSYFAMKVMDKASLASRKKLLRAQT---EKEI 246 Query: 190 LSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVS 369 L L HP LP+L ET M +C GGDL+ LR+ Q + F AV+FY AE++ Sbjct: 247 LQCLDHPFLPTLYTHFETDKFSCLVMEFCPGGDLHTLRQRQRGKYFPEQAVKFYVAEILL 306 Query: 370 ALADLHAAGIAYRDLKPEN 426 A+ LH GI YRDLKPEN Sbjct: 307 AMEYLHMLGIIYRDLKPEN 325
>KPK7_ARATH (Q05999) Putative serine/threonine-protein kinase PK7 (EC 2.7.11.1)| Length = 578 Score = 83.2 bits (204), Expect = 2e-16 Identities = 49/128 (38%), Positives = 66/128 (51%), Gaps = 3/128 (2%) Frame = +1 Query: 52 LGRGAMGTVFL---VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPS 222 LG G +G V+L + +A+KV ++ + A E +L L HP LP+ Sbjct: 188 LGGGDIGNVYLAELIGTGVSFAVKVMEKAAIAARKKLVRAQT---EKEILQSLDHPFLPT 244 Query: 223 LLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIA 402 L ET M +C GGDL+ LR+ Q + F A RFY AE++ A+ LH GI Sbjct: 245 LYSHFETEMNSCLVMEFCPGGDLHSLRQKQRGKYFPEQAARFYVAEVLLAMEYLHMLGII 304 Query: 403 YRDLKPEN 426 YRDLKPEN Sbjct: 305 YRDLKPEN 312
>PHOT1_ARATH (O48963) Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl| protein 1) (Root phototropism protein 1) Length = 996 Score = 77.0 bits (188), Expect = 2e-14 Identities = 53/139 (38%), Positives = 67/139 (48%), Gaps = 3/139 (2%) Frame = +1 Query: 19 IDLPSARAARVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSV 189 I L + + LG G G+V LV D +A+K D+ A E + Sbjct: 658 IGLKHFKPVKPLGSGDTGSVHLVELVGTDQLFAMKAMDK---AVMLNRNKVHRARAEREI 714 Query: 190 LSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVS 369 L L HP LP+L +T + Y GG+L L QP +V AVRFYAA++V Sbjct: 715 LDLLDHPFLPALYASFQTKTHICLITDYYPGGELFMLLDRQPRKVLKEDAVRFYAAQVVV 774 Query: 370 ALADLHAAGIAYRDLKPEN 426 AL LH GI YRDLKPEN Sbjct: 775 ALEYLHCQGIIYRDLKPEN 793
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 73.2 bits (178), Expect = 2e-13 Identities = 51/144 (35%), Positives = 68/144 (47%), Gaps = 3/144 (2%) Frame = +1 Query: 4 TGVMDIDLPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXX 174 +GV + L + +VLG+G G V L A YA+K+ + Sbjct: 256 SGVKKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLT-- 313 Query: 175 WEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYA 354 E VL HP L SL +T D L + M Y GG+L +R+F+ RFY Sbjct: 314 -ESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGEL--FWHLSHERIFTEDRTRFYG 370 Query: 355 AELVSALADLHAAGIAYRDLKPEN 426 AE++SAL LH+ GI YRDLK EN Sbjct: 371 AEIISALGYLHSQGIIYRDLKLEN 394
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 72.8 bits (177), Expect = 3e-13 Identities = 47/139 (33%), Positives = 66/139 (47%), Gaps = 3/139 (2%) Frame = +1 Query: 19 IDLPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSV 189 + L + + LG G G+V LV YA+K ++ E + Sbjct: 572 VGLHHFKPIKPLGSGDTGSVHLVELKGTGELYAMKAMEKTMMLNRNKAHRACI---EREI 628 Query: 190 LSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVS 369 +S L HP LP+L +T + +C GG+L L QP ++ + + RFYAAE+V Sbjct: 629 ISLLDHPFLPTLYASFQTSTHVCLITDFCPGGELFALLDRQPMKILTEDSARFYAAEVVI 688 Query: 370 ALADLHAAGIAYRDLKPEN 426 L LH GI YRDLKPEN Sbjct: 689 GLEYLHCLGIVYRDLKPEN 707
>NRC2_NEUCR (O42626) Serine/threonine-protein kinase nrc-2 (EC 2.7.11.1)| (Nonrepressible conidiation protein 2) Length = 623 Score = 72.0 bits (175), Expect = 5e-13 Identities = 42/130 (32%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +++G+G +G V+LV YA+KV ++ E +L+ HP + Sbjct: 246 KLIGKGDVGKVYLVKEKKSGRLYAMKVLSKKEMIKRNKIKRALA---EQEILATSNHPFI 302 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L ++ D L M YC+GG+ + +P + RFYAAE+ +AL LH G Sbjct: 303 VTLYHSFQSEDYLYLCMEYCSGGEFFRALQTRPGKCIPEDDARFYAAEVTAALEYLHLMG 362 Query: 397 IAYRDLKPEN 426 YRDLKPEN Sbjct: 363 FIYRDLKPEN 372
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 71.2 bits (173), Expect = 9e-13 Identities = 50/130 (38%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 152 KLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLT---ESRVLKNTRHPFL 208 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 SL +T D L + M Y GG+L +RVFS RFY AE+VSAL LH+ Sbjct: 209 TSLKYSFQTKDRLCFVMEYVNGGEL--FFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266 Query: 397 IAYRDLKPEN 426 I YRDLK EN Sbjct: 267 IVYRDLKLEN 276
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 71.2 bits (173), Expect = 9e-13 Identities = 50/130 (38%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 152 KLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLT---ESRVLKNTRHPFL 208 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 SL +T D L + M Y GG+L +RVFS RFY AE+VSAL LH+ Sbjct: 209 TSLKYSFQTKDRLCFVMEYVNGGEL--FFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266 Query: 397 IAYRDLKPEN 426 I YRDLK EN Sbjct: 267 IVYRDLKLEN 276
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 71.2 bits (173), Expect = 9e-13 Identities = 50/130 (38%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 152 KLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLT---ESRVLKNTRHPFL 208 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 SL +T D L + M Y GG+L +RVFS RFY AE+VSAL LH+ Sbjct: 209 TSLKYSFQTKDRLCFVMEYVNGGEL--FFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266 Query: 397 IAYRDLKPEN 426 I YRDLK EN Sbjct: 267 IVYRDLKLEN 276
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 70.5 bits (171), Expect = 2e-12 Identities = 48/143 (33%), Positives = 71/143 (49%), Gaps = 3/143 (2%) Frame = +1 Query: 7 GVMDIDLPSARAARVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXW 177 GV D +L ++G+G+ G V V YA+KV ++ Sbjct: 116 GVADFEL-----LNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLS--- 167 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E ++L ++ HP L +L +T D L + + Y GG+L Q D+ F+ VR+Y A Sbjct: 168 ERNILQKINHPFLVNLNYSFQTEDKLYFILDYVNGGEL--FYHLQKDKKFTEDRVRYYGA 225 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 E+V AL LH +G+ YRDLKPEN Sbjct: 226 EIVLALEHLHLSGVIYRDLKPEN 248
>SGK1_RABIT (Q9XT18) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 70.1 bits (170), Expect = 2e-12 Identities = 47/130 (36%), Positives = 65/130 (50%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G+ G V L A +A YA+KV +++ +L + HP L Sbjct: 102 KVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSE--RNVLLKNVKHPFL 159 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T D L + + Y GG+L Q +R F RFYAAE+ SAL LH+ Sbjct: 160 VGLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLN 217 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 218 IVYRDLKPEN 227
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 70.1 bits (170), Expect = 2e-12 Identities = 47/130 (36%), Positives = 65/130 (50%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G+ G V L A +A YA+KV +++ +L + HP L Sbjct: 102 KVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSE--RNVLLKNVKHPFL 159 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T D L + + Y GG+L Q +R F RFYAAE+ SAL LH+ Sbjct: 160 VGLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLN 217 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 218 IVYRDLKPEN 227
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 69.7 bits (169), Expect = 3e-12 Identities = 43/139 (30%), Positives = 68/139 (48%), Gaps = 3/139 (2%) Frame = +1 Query: 19 IDLPSARAARVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSV 189 ++ S R+LG+G +G V+L+ + +ALKV ++ E + Sbjct: 319 VEPQSFEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLT---EQEI 375 Query: 190 LSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVS 369 L+ HP + +L +T D L M YC GG+ + + + + +FYA+E+V+ Sbjct: 376 LATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVA 435 Query: 370 ALADLHAAGIAYRDLKPEN 426 AL LH G YRDLKPEN Sbjct: 436 ALEYLHLLGFIYRDLKPEN 454
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 69.7 bits (169), Expect = 3e-12 Identities = 51/151 (33%), Positives = 70/151 (46%), Gaps = 12/151 (7%) Frame = +1 Query: 10 VMDIDLPSARAA---------RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXX 153 +M++ + ARA ++LG+G G V LV A YA+K+ + Sbjct: 135 MMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEV 194 Query: 154 XXXXXXXWEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSP 333 E VL HP L +L +T D L + M Y GGDL +RVF+ Sbjct: 195 AHTVT---ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGDL--FFHLSRERVFTE 249 Query: 334 AAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 RFY AE+VSAL LH+ + YRD+K EN Sbjct: 250 DRARFYGAEIVSALEYLHSTDVVYRDIKLEN 280
>SGK1_MOUSE (Q9WVC6) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 69.7 bits (169), Expect = 3e-12 Identities = 47/130 (36%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G+ G V L AE YA+KV +++ +L + HP L Sbjct: 102 KVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSE--RNVLLKNVKHPFL 159 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T D L + + Y GG+L Q +R F RFYAAE+ SAL LH+ Sbjct: 160 VGLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLN 217 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 218 IVYRDLKPEN 227
>SGK1_HUMAN (O00141) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 69.7 bits (169), Expect = 3e-12 Identities = 47/130 (36%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G+ G V L AE YA+KV +++ +L + HP L Sbjct: 102 KVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSE--RNVLLKNVKHPFL 159 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T D L + + Y GG+L Q +R F RFYAAE+ SAL LH+ Sbjct: 160 VGLHFSFQTADKLYFVLDYINGGEL--FYHLQRERCFLEPRARFYAAEIASALGYLHSLN 217 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 218 IVYRDLKPEN 227
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 69.3 bits (168), Expect = 4e-12 Identities = 46/130 (35%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFL---VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG G+ TV L +A EYA+K+ ++R E V+SRL HP Sbjct: 89 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFF 145 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L + + L + + Y G+L L+ + F RFY AE+VSAL LH G Sbjct: 146 VKLYFTFQDDEKLYFGLSYAKNGEL--LKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 203 Query: 397 IAYRDLKPEN 426 I +RDLKPEN Sbjct: 204 IIHRDLKPEN 213
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 69.3 bits (168), Expect = 4e-12 Identities = 46/130 (35%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFL---VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG G+ TV L +A EYA+K+ ++R E V+SRL HP Sbjct: 89 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFF 145 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L + + L + + Y G+L L+ + F RFY AE+VSAL LH G Sbjct: 146 VKLYFTFQDDEKLYFGLSYAKNGEL--LKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 203 Query: 397 IAYRDLKPEN 426 I +RDLKPEN Sbjct: 204 IIHRDLKPEN 213
>KAPC_ASCSU (P49673) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 337 Score = 69.3 bits (168), Expect = 4e-12 Identities = 50/128 (39%), Positives = 65/128 (50%), Gaps = 3/128 (2%) Frame = +1 Query: 52 LGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPS 222 +G G+ G V+LV A++ +ALK R E +LSRL+HP + Sbjct: 35 IGTGSFGRVYLVQHRASEQYFALKKMAIREVVSMRQTEHVHS---EKRLLSRLSHPFIVK 91 Query: 223 LLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIA 402 + + L Y AGG+L RA R FS + RFYAAE+V AL LH+ IA Sbjct: 92 MYCASWDKYNLYMLFEYLAGGELFSYLRAS--RTFSNSMARFYAAEIVCALQYLHSKNIA 149 Query: 403 YRDLKPEN 426 YRDLKPEN Sbjct: 150 YRDLKPEN 157
>KAD5_SCHPO (Q09831) Probable serine/threonine-protein kinase C4G8.05 (EC| 2.7.11.1) Length = 566 Score = 69.3 bits (168), Expect = 4e-12 Identities = 42/129 (32%), Positives = 62/129 (48%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 +LG+G +G V+LV YA+KV ++ E +L+ HP + Sbjct: 200 LLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFA---EQHILATSNHPFIV 256 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 +L ++ + L M YC GG+ + +P R S +FY AE+ +AL LH G Sbjct: 257 TLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLMGF 316 Query: 400 AYRDLKPEN 426 YRDLKPEN Sbjct: 317 IYRDLKPEN 325
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 69.3 bits (168), Expect = 4e-12 Identities = 46/130 (35%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFL---VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG G+ TV L +A EYA+K+ ++R E V+SRL HP Sbjct: 86 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTR---ERDVMSRLDHPFF 142 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L + + L + + Y G+L L+ + F RFY AE+VSAL LH G Sbjct: 143 VKLYFTFQDDEKLYFGLSYAKNGEL--LKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 200 Query: 397 IAYRDLKPEN 426 I +RDLKPEN Sbjct: 201 IIHRDLKPEN 210
>KN8R_YEAST (P53739) Probable serine/threonine-protein kinase YNR047W (EC| 2.7.11.1) Length = 893 Score = 68.9 bits (167), Expect = 5e-12 Identities = 44/130 (33%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R+LG+G +G VFLV + YALKV + E +L+ HP + Sbjct: 500 RLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLT---EQEILATSNHPFI 556 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L ++ D L M YC GG+ + + + RFYA+E+ +AL LH G Sbjct: 557 VTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLG 616 Query: 397 IAYRDLKPEN 426 YRDLKPEN Sbjct: 617 FIYRDLKPEN 626
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 68.2 bits (165), Expect = 8e-12 Identities = 51/153 (33%), Positives = 70/153 (45%), Gaps = 12/153 (7%) Frame = +1 Query: 4 TGVMDIDLPSARAA---------RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGX 147 T M++ + ARA ++LG+G G V LV A YA+K+ + Sbjct: 133 TEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKD 192 Query: 148 XXXXXXXXXWEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVF 327 E VL HP L +L +T D L + M Y GG+L +RVF Sbjct: 193 EVAHTVT---ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGEL--FFHLSRERVF 247 Query: 328 SPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 + RFY AE+VSAL LH+ + YRD+K EN Sbjct: 248 TEERARFYGAEIVSALEYLHSRDVVYRDIKLEN 280
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 68.2 bits (165), Expect = 8e-12 Identities = 46/130 (35%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 161 KLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTLT---ESRVLQNTKHPFL 217 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L +T D L + M Y GG+L +RVF+ RFY AE+VSAL LH+ Sbjct: 218 TALKYAFQTSDRLCFVMEYANGGEL--FFHLSRERVFTEDRARFYGAEIVSALEYLHSRN 275 Query: 397 IAYRDLKPEN 426 + YRD+K EN Sbjct: 276 VVYRDIKLEN 285
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 67.8 bits (164), Expect = 1e-11 Identities = 46/133 (34%), Positives = 67/133 (50%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV + YA+KV + + E ++L+ ++H Sbjct: 108 KVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKAT----LKVRDRQRTKLERNILAHISH 163 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL AL LH Sbjct: 164 PFIVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEDDVKFYLAELTLALEHLH 221 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 222 SLGIVYRDLKPEN 234 Score = 28.1 bits (61), Expect = 9.0 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 1/102 (0%) Frame = +1 Query: 124 RRSHAPGXXXXXXXXXXWEVSVLSRLAHPH-LPSLLGRAETPDLLAWAMPYCAGGDLNEL 300 RR +A EV +L R +H + L E + C GG+L + Sbjct: 477 RRKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLD- 535 Query: 301 RRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 + + S V A L++A+ LH+ +A+RDL N Sbjct: 536 KLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAAN 577
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 67.8 bits (164), Expect = 1e-11 Identities = 46/130 (35%), Positives = 61/130 (46%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 160 KLLGKGTFGKVILVREKATGLYYAMKILRKEVIIAKDEVAHTLT---ESRVLQNTKHPFL 216 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T D L + M Y GG+L +RVF+ RFY AE+VSAL LH+ Sbjct: 217 TGLKYAFQTSDRLCFVMEYANGGEL--FFHLSRERVFTEDRARFYGAEIVSALEYLHSRN 274 Query: 397 IAYRDLKPEN 426 + YRD+K EN Sbjct: 275 VVYRDIKLEN 284
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 67.8 bits (164), Expect = 1e-11 Identities = 48/131 (36%), Positives = 67/131 (51%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSR-LAHPH 213 +V+G+G G V L ++ YA+KV ++S E SVL + + HP Sbjct: 99 KVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMA---ERSVLLKNVRHPF 155 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L L +TP+ L + + Y GG+L Q +R F RFYAAE+ SA+ LH+ Sbjct: 156 LVGLRYSFQTPEKLYFVLDYVNGGEL--FFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213 Query: 394 GIAYRDLKPEN 426 I YRDLKPEN Sbjct: 214 NIIYRDLKPEN 224
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 67.8 bits (164), Expect = 1e-11 Identities = 49/130 (37%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 RVLG+G+ G V L YA+KV + +S+ HP L Sbjct: 359 RVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARN--HPFL 416 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +TPD L + M + GGDL + Q R F A RFYAAE++SAL LH G Sbjct: 417 TQLFCCFQTPDRLFFVMEFVNGGDL--MFHIQKSRRFDEARARFYAAEIISALMFLHEKG 474 Query: 397 IAYRDLKPEN 426 I YRDLK +N Sbjct: 475 IIYRDLKLDN 484
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 67.8 bits (164), Expect = 1e-11 Identities = 49/130 (37%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 RVLG+G+ G V L YA+KV + +S+ HP L Sbjct: 359 RVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARN--HPFL 416 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +TPD L + M + GGDL + Q R F A RFYAAE++SAL LH G Sbjct: 417 TQLFCCFQTPDRLFFVMEFVNGGDL--MFHIQKSRRFDEARARFYAAEIISALMFLHEKG 474 Query: 397 IAYRDLKPEN 426 I YRDLK +N Sbjct: 475 IIYRDLKLDN 484
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 67.4 bits (163), Expect = 1e-11 Identities = 46/130 (35%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 156 KLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVT---ESRVLQNTRHPFL 212 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L +T D L + M Y GG+L +RVF+ RFY AE+VSAL LH+ Sbjct: 213 TALKYAFQTHDRLCFVMEYANGGEL--FFHLSRERVFTEDRARFYGAEIVSALEYLHSRD 270 Query: 397 IAYRDLKPEN 426 + YRD+K EN Sbjct: 271 VVYRDIKLEN 280
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 67.0 bits (162), Expect = 2e-11 Identities = 49/130 (37%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 RVLG+G+ G V L YA+KV + +S+ HP L Sbjct: 358 RVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLARN--HPFL 415 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +TPD L + M + GGDL + Q R F A RFYAAE++SAL LH G Sbjct: 416 TQLFCCFQTPDRLFFVMEFVNGGDL--MFHIQKSRRFDEARARFYAAEIISALMFLHDKG 473 Query: 397 IAYRDLKPEN 426 I YRDLK +N Sbjct: 474 IIYRDLKLDN 483
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 66.6 bits (161), Expect = 2e-11 Identities = 48/133 (36%), Positives = 66/133 (49%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLV----AADAE--YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV +DA YA+KV + + E +L + H Sbjct: 72 KVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKAT----LKVRDRVRTKMERDILVEVNH 127 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL AL LH Sbjct: 128 PFIVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKFYLAELALALDHLH 185 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 186 SLGIIYRDLKPEN 198 Score = 35.4 bits (80), Expect = 0.056 Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 1/114 (0%) Frame = +1 Query: 88 AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWA 264 A + E+A+K+ D+ P E+ +L R HP++ +L + + Sbjct: 443 ATNMEFAVKIIDKSKRDPTE----------EIEILLRYGQHPNIITLKDVYDDGKYVYVV 492 Query: 265 MPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L L + + FS + + LHA G+ +RDLKP N Sbjct: 493 TELMKGGEL--LDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSN 544
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 66.6 bits (161), Expect = 2e-11 Identities = 48/133 (36%), Positives = 66/133 (49%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLV----AADAE--YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV +DA YA+KV + + E +L + H Sbjct: 72 KVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKAT----LKVRDRVRTKMERDILVEVNH 127 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL AL LH Sbjct: 128 PFIVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKFYLAELALALDHLH 185 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 186 SLGIIYRDLKPEN 198 Score = 35.4 bits (80), Expect = 0.056 Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 1/114 (0%) Frame = +1 Query: 88 AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWA 264 A + E+A+K+ D+ P E+ +L R HP++ +L + + Sbjct: 443 ATNMEFAVKIIDKSKRDPTE----------EIEILLRYGQHPNIITLKDVYDDGKYVYVV 492 Query: 265 MPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L L + + FS + + LHA G+ +RDLKP N Sbjct: 493 TELMKGGEL--LDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSN 544
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 66.6 bits (161), Expect = 2e-11 Identities = 47/133 (35%), Positives = 65/133 (48%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV A YA+KV + + E +L+ + H Sbjct: 63 KVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKAT----LKVRDRVRSKMERDILAEVNH 118 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL AL LH Sbjct: 119 PFIVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKFYLAELALALDHLH 176 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 177 SLGIIYRDLKPEN 189 Score = 44.7 bits (104), Expect = 9e-05 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Frame = +1 Query: 88 AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWA 264 A D EYA+K+ D+ P E+ +L R HP++ +L + + Sbjct: 436 ATDTEYAVKIIDKSKRDPSE----------EIEILLRYGQHPNIITLKDVYDDGKFVYLV 485 Query: 265 MPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 M GG+L L R R FS + + LH+ G+ +RDLKP N Sbjct: 486 MELMRGGEL--LDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSN 537
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 66.2 bits (160), Expect = 3e-11 Identities = 47/133 (35%), Positives = 64/133 (48%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV A YA+KV + + E +L+ + H Sbjct: 63 KVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKAT----LKVRDRVRSKMERDILAEVNH 118 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL AL LH Sbjct: 119 PFIVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKFYLAELALALDHLH 176 Query: 388 AAGIAYRDLKPEN 426 GI YRDLKPEN Sbjct: 177 GLGIIYRDLKPEN 189 Score = 44.7 bits (104), Expect = 9e-05 Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 1/114 (0%) Frame = +1 Query: 88 AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWA 264 A DAEYA+K+ D+ P E+ +L R HP++ +L + + Sbjct: 436 ATDAEYAVKIIDKSKRDPSE----------EIEILLRYGQHPNIITLKDVYDDGKYVYLV 485 Query: 265 MPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 M GG+L L R R FS + + LH+ G+ +RDLKP N Sbjct: 486 MELMRGGEL--LDRILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPSN 537
>SGK2_MOUSE (Q9QZS5) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 367 Score = 65.9 bits (159), Expect = 4e-11 Identities = 44/130 (33%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G G V L ++ YA+KV ++S +L + HP L Sbjct: 39 KVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAE--RNVLLKNVRHPFL 96 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +TP+ L + + Y GG+L Q +R F RFY AE+ SA+ LH+ Sbjct: 97 VGLRYSFQTPEKLYFVLDYVNGGEL--FFHLQRERRFLEPRARFYTAEVASAIGYLHSLN 154 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 155 IIYRDLKPEN 164
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 65.5 bits (158), Expect = 5e-11 Identities = 48/131 (36%), Positives = 65/131 (49%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPH 213 +VLG+G+ G V L D YA+KV + + E +L+ A HP Sbjct: 307 KVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMT---EKRILALAANHPF 363 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L +L +TPD L + M Y GGDL + + Q R F + FYAAE+ AL LH Sbjct: 364 LTALHSCFQTPDRLFFVMEYVNGGDL--MFQIQKARRFEASRAAFYAAEVTLALQFLHTH 421 Query: 394 GIAYRDLKPEN 426 G+ YRDLK +N Sbjct: 422 GVIYRDLKLDN 432
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 65.5 bits (158), Expect = 5e-11 Identities = 49/131 (37%), Positives = 63/131 (48%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A A YA+K+ + E VL HP L Sbjct: 154 KLLGKGTFGKVILVKEKATAAYYAMKILKKEVIVAKDEVAHTLT---ENRVLQNSRHPSL 210 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA-A 393 +L +T D L + M Y GG+L +RVFS RFY AE+VSAL LH+ Sbjct: 211 TALKYSFQTHDRLCFVMEYANGGEL--FFHLSRERVFSEDRARFYGAEIVSALDYLHSEK 268 Query: 394 GIAYRDLKPEN 426 + YRDLK EN Sbjct: 269 EVVYRDLKLEN 279
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 65.5 bits (158), Expect = 5e-11 Identities = 47/133 (35%), Positives = 63/133 (47%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV A YA+KV + S E +L + H Sbjct: 77 KVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKAS----LKVRDRVRTKMERDILVEVNH 132 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGD+ R + +F+ V+FY AEL AL LH Sbjct: 133 PFIVKLHYAFQTEGKLYLILDFLRGGDV--FTRLSKEVLFTEEDVKFYLAELALALDHLH 190 Query: 388 AAGIAYRDLKPEN 426 GI YRDLKPEN Sbjct: 191 QLGIVYRDLKPEN 203 Score = 33.1 bits (74), Expect = 0.28 Identities = 27/110 (24%), Positives = 44/110 (40%), Gaps = 1/110 (0%) Frame = +1 Query: 100 EYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYC 276 E+A+K+ D+ P E+ +L R HP++ +L + + Sbjct: 451 EFAVKIIDKSKRDPSE----------EIEILMRYGQHPNIITLKDVFDDGRYVYLVTDLM 500 Query: 277 AGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L L R + FS + + LH G+ +RDLKP N Sbjct: 501 KGGEL--LDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSN 548
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 65.1 bits (157), Expect = 7e-11 Identities = 48/138 (34%), Positives = 67/138 (48%), Gaps = 4/138 (2%) Frame = +1 Query: 25 LPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLS 195 L + RVLG G G V+L+ + YA+K ++ A E S+LS Sbjct: 333 LKEFKQIRVLGTGTFGKVYLIQNTKDGCYYAMKCLNK---AYVVQLKQVEHLNSEKSILS 389 Query: 196 RLAHPHLPSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSA 372 + HP + +L + L Y AGG++ LR++ FS + +FYAAE+V A Sbjct: 390 SIHHPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMK---FSNSTAKFYAAEIVLA 446 Query: 373 LADLHAAGIAYRDLKPEN 426 L LH I YRDLKPEN Sbjct: 447 LEFLHKQNIVYRDLKPEN 464
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 64.7 bits (156), Expect = 9e-11 Identities = 46/133 (34%), Positives = 65/133 (48%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV A+ YA+KV + + E +L+ + H Sbjct: 66 KVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKAT----LKVRDRVRTKMERDILADVHH 121 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL L LH Sbjct: 122 PFVVRLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKFYLAELALGLDHLH 179 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 180 SLGIIYRDLKPEN 192 Score = 37.4 bits (85), Expect = 0.015 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 1/110 (0%) Frame = +1 Query: 100 EYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYC 276 EYA+KV D+ P E+ +L R HP++ +L E + + Sbjct: 441 EYAVKVIDKSKRDPSE----------EIEILRRYGQHPNIITLKDVYEECNSIYLVTELM 490 Query: 277 AGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L L R + FS + + LH+ G+ +RDLKP N Sbjct: 491 RGGEL--LDRILRQKFFSEREACSVLFTVCKTVEYLHSQGVVHRDLKPSN 538
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 64.7 bits (156), Expect = 9e-11 Identities = 48/130 (36%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +VLG+G+ G V L D YA+KV ++ + L+R HP+L Sbjct: 411 KVLGKGSFGKVMLAELKGKDEVYAVKVL-KKDVILQDDDVDCTMTEKRILALAR-KHPYL 468 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T D L + M Y GGDL + + Q R F RFYAAE+ SAL LH G Sbjct: 469 TQLYCCFQTKDRLFFVMEYVNGGDL--MFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHG 526 Query: 397 IAYRDLKPEN 426 + YRDLK +N Sbjct: 527 VIYRDLKLDN 536
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 64.7 bits (156), Expect = 9e-11 Identities = 46/133 (34%), Positives = 65/133 (48%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV A+ YA+KV + + E +L+ + H Sbjct: 66 KVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKAT----LKVRDRVRTKMERDILADVHH 121 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL L LH Sbjct: 122 PFVVRLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKFYLAELALGLDHLH 179 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 180 SLGIIYRDLKPEN 192 Score = 38.1 bits (87), Expect = 0.009 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 1/110 (0%) Frame = +1 Query: 100 EYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYC 276 EYA+KV D+ P E+ +L R HP++ +L + + + Sbjct: 441 EYAVKVIDKTKRDPSE----------EIEILRRYGQHPNIIALKDVYKEGNSIYVVTELM 490 Query: 277 AGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L L R + FS + + +LH+ G+ +RDLKP N Sbjct: 491 RGGEL--LDRILRQKFFSEREASSVLFTVCKTVENLHSQGVVHRDLKPSN 538
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 64.7 bits (156), Expect = 9e-11 Identities = 48/130 (36%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +VLG+G+ G V L D YA+KV ++ + L+R HP+L Sbjct: 412 KVLGKGSFGKVMLAELKGKDEVYAVKVL-KKDVILQDDDVDCTMTEKRILALAR-KHPYL 469 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T D L + M Y GGDL + + Q R F RFYAAE+ SAL LH G Sbjct: 470 TQLYCCFQTKDRLFFVMEYVNGGDL--MFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHG 527 Query: 397 IAYRDLKPEN 426 + YRDLK +N Sbjct: 528 VIYRDLKLDN 537
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 64.7 bits (156), Expect = 9e-11 Identities = 48/130 (36%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +VLG+G+ G V L D YA+KV ++ + L+R HP+L Sbjct: 412 KVLGKGSFGKVMLAELKGKDEVYAVKVL-KKDVILQDDDVDCTMTEKRILALAR-KHPYL 469 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T D L + M Y GGDL + + Q R F RFYAAE+ SAL LH G Sbjct: 470 TQLYCCFQTKDRLFFVMEYVNGGDL--MFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHG 527 Query: 397 IAYRDLKPEN 426 + YRDLK +N Sbjct: 528 VIYRDLKLDN 537
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 64.7 bits (156), Expect = 9e-11 Identities = 48/131 (36%), Positives = 62/131 (47%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 154 KLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT---ENRVLQNSRHPFL 210 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA-A 393 +L +T D L + M Y GG+L +RVFS RFY AE+VSAL LH+ Sbjct: 211 TALKYSFQTHDRLCFVMEYANGGEL--FFHLSRERVFSEDRARFYGAEIVSALDYLHSEK 268 Query: 394 GIAYRDLKPEN 426 + YRDLK EN Sbjct: 269 NVVYRDLKLEN 279
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 64.7 bits (156), Expect = 9e-11 Identities = 48/131 (36%), Positives = 62/131 (47%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 154 KLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT---ENRVLQNSRHPFL 210 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA-A 393 +L +T D L + M Y GG+L +RVFS RFY AE+VSAL LH+ Sbjct: 211 TALKYSFQTHDRLCFVMEYANGGEL--FFHLSRERVFSEDRARFYGAEIVSALDYLHSEK 268 Query: 394 GIAYRDLKPEN 426 + YRDLK EN Sbjct: 269 NVVYRDLKLEN 279
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 64.7 bits (156), Expect = 9e-11 Identities = 48/131 (36%), Positives = 62/131 (47%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 154 KLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT---ENRVLQNSRHPFL 210 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA-A 393 +L +T D L + M Y GG+L +RVFS RFY AE+VSAL LH+ Sbjct: 211 TALKYSFQTHDRLCFVMEYANGGEL--FFHLSRERVFSEDRARFYGAEIVSALDYLHSEK 268 Query: 394 GIAYRDLKPEN 426 + YRDLK EN Sbjct: 269 NVVYRDLKLEN 279
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 64.7 bits (156), Expect = 9e-11 Identities = 48/131 (36%), Positives = 62/131 (47%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 175 KLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT---ENRVLQNSRHPFL 231 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA-A 393 +L +T D L + M Y GG+L +RVFS RFY AE+VSAL LH+ Sbjct: 232 TALKYSFQTHDRLCFVMEYANGGEL--FFHLSRERVFSEDRARFYGAEIVSALDYLHSEK 289 Query: 394 GIAYRDLKPEN 426 + YRDLK EN Sbjct: 290 NVVYRDLKLEN 300
>SGK2_RAT (Q8R4U9) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) (Fragment) Length = 302 Score = 64.3 bits (155), Expect = 1e-10 Identities = 43/130 (33%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G G V L ++ YA+KV ++S +L + HP L Sbjct: 22 KVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAE--RNVLLKNVRHPFL 79 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +TP+ L + + Y GG+L Q + F RFY AE+ SA+ LH+ Sbjct: 80 VGLRYSFQTPEKLYFVLDYVNGGEL--FFHLQREHRFLEPRARFYTAEVASAIGYLHSLN 137 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 138 IIYRDLKPEN 147
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 64.3 bits (155), Expect = 1e-10 Identities = 47/131 (35%), Positives = 62/131 (47%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++LG+G G V LV A YA+K+ + E VL HP L Sbjct: 155 KLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT---ENRVLQNSRHPFL 211 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA-A 393 +L +T D L + M Y GG+L +R+FS RFY AE+VSAL LH+ Sbjct: 212 TALKYSFQTHDRLCFVMEYANGGEL--FFHLSRERIFSEDRARFYGAEIVSALDYLHSEK 269 Query: 394 GIAYRDLKPEN 426 + YRDLK EN Sbjct: 270 NVVYRDLKLEN 280
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 63.2 bits (152), Expect = 3e-10 Identities = 45/133 (33%), Positives = 63/133 (47%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE------YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV YA+KV + + E +L+ + H Sbjct: 66 KVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKAT----LKVRDRVRTKMERDILADVNH 121 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL L LH Sbjct: 122 PFVVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKFYLAELALGLDHLH 179 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 180 SLGIIYRDLKPEN 192 Score = 39.3 bits (90), Expect = 0.004 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Frame = +1 Query: 88 AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWA 264 A + EYA+KV D+ P E+ +L R HP++ +L + + Sbjct: 439 ATNMEYAVKVIDKSKRDPSE----------EIEILLRYGQHPNIITLKDVYDDSKHVYLV 488 Query: 265 MPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L L + + FS F + + LH+ G+ +RDLKP N Sbjct: 489 TELMRGGEL--LDKILRQKFFSEREASFVLYTISKTVEYLHSQGVVHRDLKPSN 540
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 63.2 bits (152), Expect = 3e-10 Identities = 45/133 (33%), Positives = 63/133 (47%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE------YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV YA+KV + + E +L+ + H Sbjct: 66 KVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKAT----LKVRDRVRTKMERDILADVNH 121 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL L LH Sbjct: 122 PFVVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKFYLAELALGLDHLH 179 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 180 SLGIIYRDLKPEN 192 Score = 38.5 bits (88), Expect = 0.007 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Frame = +1 Query: 88 AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWA 264 A + EYA+KV D+ P E+ +L R HP++ +L + + Sbjct: 439 ATNMEYAVKVIDKSKRDPSE----------EIEILLRYGQHPNIITLKDVYDDGKHVYLV 488 Query: 265 MPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L L + + FS F + + LH+ G+ +RDLKP N Sbjct: 489 TELMRGGEL--LDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSN 540
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 63.2 bits (152), Expect = 3e-10 Identities = 45/133 (33%), Positives = 63/133 (47%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE------YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV YA+KV + + E +L+ + H Sbjct: 66 KVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKAT----LKVRDRVRTKMERDILADVNH 121 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL L LH Sbjct: 122 PFVVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKFYLAELALGLDHLH 179 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 180 SLGIIYRDLKPEN 192 Score = 38.9 bits (89), Expect = 0.005 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Frame = +1 Query: 88 AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWA 264 A + EYA+KV D+ P E+ +L R HP++ +L + + Sbjct: 428 ATNMEYAVKVIDKSKRDPSE----------EIEILLRYGQHPNIITLKDVYDDGKHVYLV 477 Query: 265 MPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L L + + FS F + + LH+ G+ +RDLKP N Sbjct: 478 TELMRGGEL--LDKILRQKFFSEREASFVLHTISKTVEYLHSQGVVHRDLKPSN 529
>GRK1_CAEEL (Q09537) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 642 Score = 63.2 bits (152), Expect = 3e-10 Identities = 49/140 (35%), Positives = 62/140 (44%), Gaps = 4/140 (2%) Frame = +1 Query: 19 IDLPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSV 189 +D + R RVLG+G G V A YALK +++ E + Sbjct: 198 VDKHTFRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLN---EKQI 254 Query: 190 LSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLN-ELRRAQPDRVFSPAAVRFYAAELV 366 L R+ P + SL ET D L + GGDL L P F V+FYAAE+ Sbjct: 255 LQRINSPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGG-FDEKRVQFYAAEIT 313 Query: 367 SALADLHAAGIAYRDLKPEN 426 L LH+ I YRDLKPEN Sbjct: 314 LGLQHLHSERILYRDLKPEN 333
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 62.8 bits (151), Expect = 3e-10 Identities = 45/133 (33%), Positives = 65/133 (48%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG+G+ G VFLV ++ YA+KV + + E +L+ + H Sbjct: 84 KVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKAT----LKVRDRVRTKIERDILADVNH 139 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + + GGDL R + +F+ V+FY AEL L LH Sbjct: 140 PFVVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKFYLAELALGLDHLH 197 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 198 SLGIIYRDLKPEN 210 Score = 35.4 bits (80), Expect = 0.056 Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 1/110 (0%) Frame = +1 Query: 100 EYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYC 276 EYA+KV D+ P E+ +L R HP++ +L + + Sbjct: 460 EYAVKVIDKSKRDPSE----------EIEILLRYGQHPNIITLKDVYDDGKYVYLVTELM 509 Query: 277 AGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L L + + FS + + LH+ G+ +RDLKP N Sbjct: 510 RGGEL--LDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSN 557
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 62.4 bits (150), Expect = 4e-10 Identities = 47/131 (35%), Positives = 63/131 (48%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA-HPH 213 +VLG+G+ G V L D YA+K+ + E +LS A HP Sbjct: 382 KVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMC---EKRILSLAAKHPF 438 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L +L +T D L + M Y GGDL + + Q R F + RFYAAE+ AL LH Sbjct: 439 LTALHSSFQTSDRLFFVMEYVNGGDL--MFQIQRARKFDESRARFYAAEVTCALQFLHRN 496 Query: 394 GIAYRDLKPEN 426 + YRDLK +N Sbjct: 497 DVIYRDLKLDN 507
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 62.4 bits (150), Expect = 4e-10 Identities = 50/140 (35%), Positives = 65/140 (46%), Gaps = 4/140 (2%) Frame = +1 Query: 19 IDLPSARAARVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSV 189 I L +VLG+G+ G V L D YA+KV + E + Sbjct: 398 ISLHDFNFIKVLGKGSFGKVMLAEKKGTDEVYAIKVLKKDVIIQDDDVECTMT---EKRI 454 Query: 190 LSRLA-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELV 366 L+ A HP L +L +T + L + M Y GGDL + + Q R F RFYAAE+ Sbjct: 455 LALSAKHPFLTALHSSFQTKERLFFVMEYVNGGDL--MFQIQRARKFDEPRARFYAAEVT 512 Query: 367 SALADLHAAGIAYRDLKPEN 426 AL LH GI YRDLK +N Sbjct: 513 LALMFLHRHGIIYRDLKLDN 532
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 62.0 bits (149), Expect = 6e-10 Identities = 47/130 (36%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +VLG+G+ G V L D YA+KV ++ + L+R HP+L Sbjct: 412 KVLGKGSFGKVMLAELKGKDEVYAVKVL-KKDVILQDDDVDCTMTEKRILALAR-KHPYL 469 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T D L + M Y GGDL + + Q R F FYAAE+ SAL LH G Sbjct: 470 TQLYCCFQTKDRLFFVMEYVNGGDL--MFQIQRSRKFDEPRSGFYAAEVTSALMFLHQHG 527 Query: 397 IAYRDLKPEN 426 + YRDLK +N Sbjct: 528 VIYRDLKLDN 537
>SGK3_MOUSE (Q9ERE3) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 61.2 bits (147), Expect = 1e-09 Identities = 43/130 (33%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G+ G V L + YA+KV ++ +L + HP L Sbjct: 166 KVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAE--RNVLLKNVKHPFL 223 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T + L + + + GG+L Q +R F RFYAAE+ SAL LH+ Sbjct: 224 VGLHYSFQTTEKLYFVLDFVNGGEL--FFHLQRERSFPEPRARFYAAEIASALGYLHSIK 281 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 282 IVYRDLKPEN 291
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 61.2 bits (147), Expect = 1e-09 Identities = 44/130 (33%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV ++ YA+KV +++ + +LSR+ HP + Sbjct: 205 QTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERY---ILSRVQHPFI 261 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L G + L M + GG+L L R F +FYAAE++ AL LH Sbjct: 262 TILWGTFQDAKNLFMVMDFAEGGELFSLLRKC--HRFPEKVAKFYAAEVILALDYLHHNQ 319 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 320 IVYRDLKPEN 329
>SGK3_HUMAN (Q96BR1) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) Length = 496 Score = 60.8 bits (146), Expect = 1e-09 Identities = 43/130 (33%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G+ G V L + YA+KV ++ +L + HP L Sbjct: 166 KVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAE--RNVLLKNVKHPFL 223 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T + L + + + GG+L Q +R F RFYAAE+ SAL LH+ Sbjct: 224 VGLHYSFQTTEKLYFVLDFVNGGEL--FFHLQRERSFPEHRARFYAAEIASALGYLHSIK 281 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 282 IVYRDLKPEN 291
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 60.8 bits (146), Expect = 1e-09 Identities = 45/130 (34%), Positives = 66/130 (50%), Gaps = 4/130 (3%) Frame = +1 Query: 49 VLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 V+G+G+ G V V E +A+KV + + E ++L ++HP + Sbjct: 158 VIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKS---EKTILQCISHPFIV 214 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLN-ELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L +T D L + + GG+L L+R + FS V+ YAAE+VSAL LH Sbjct: 215 NLHYAFQTKDKLYMVLDFVNGGELFFHLKR---EGRFSEPRVKIYAAEIVSALDHLHKQD 271 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 272 IVYRDLKPEN 281
>PKH3_ASHGO (Q753D9) Serine/threonine-protein kinase PKH3 (EC 2.7.11.1)| Length = 726 Score = 60.8 bits (146), Expect = 1e-09 Identities = 40/128 (31%), Positives = 63/128 (49%), Gaps = 3/128 (2%) Frame = +1 Query: 52 LGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPS 222 LG G+ TV+ V ++ +YA+K+ +R +++L + HP + Sbjct: 16 LGHGSYSTVYRVVERSSQHQYAIKICSKRHIIGENKVKYVTIEKNTLNLLGQANHPGIIK 75 Query: 223 LLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIA 402 L + L + M GG+L +L R Q RVFS A R Y +LV + +H+ G+ Sbjct: 76 LYYTFHDQENLYFVMDLAPGGELLQLLRRQ--RVFSEAWARHYMCQLVDTVEYIHSMGVI 133 Query: 403 YRDLKPEN 426 +RDLKPEN Sbjct: 134 HRDLKPEN 141
>GRK1_CAEBR (Q622Z7) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 640 Score = 60.8 bits (146), Expect = 1e-09 Identities = 48/140 (34%), Positives = 61/140 (43%), Gaps = 4/140 (2%) Frame = +1 Query: 19 IDLPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSV 189 +D + R RVLG+G G V A YALK +++ E + Sbjct: 197 VDKHTFRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLN---EKQI 253 Query: 190 LSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLN-ELRRAQPDRVFSPAAVRFYAAELV 366 L ++ P + SL ET D L + GGDL L P F V+FYAAE+ Sbjct: 254 LQKVNSPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGG-FDEKRVQFYAAEIT 312 Query: 367 SALADLHAAGIAYRDLKPEN 426 L LH I YRDLKPEN Sbjct: 313 LGLQHLHLEHILYRDLKPEN 332
>KS6B1_RAT (P67999) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 60.5 bits (145), Expect = 2e-09 Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 RVLG+G G VF V +A+KV + E ++L + H Sbjct: 95 RVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKA--ERNILEEVKH 152 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L+ +T L + Y +GG+L + + + +F FY AE+ AL LH Sbjct: 153 PFIVDLIYAFQTGGKLYLILEYLSGGEL--FMQLEREGIFMEDTACFYLAEISMALGHLH 210 Query: 388 AAGIAYRDLKPEN 426 GI YRDLKPEN Sbjct: 211 QKGIIYRDLKPEN 223
>KS6B1_RABIT (P67998) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 60.5 bits (145), Expect = 2e-09 Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 RVLG+G G VF V +A+KV + E ++L + H Sbjct: 95 RVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKA--ERNILEEVKH 152 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L+ +T L + Y +GG+L + + + +F FY AE+ AL LH Sbjct: 153 PFIVDLIYAFQTGGKLYLILEYLSGGEL--FMQLEREGIFMEDTACFYLAEISMALGHLH 210 Query: 388 AAGIAYRDLKPEN 426 GI YRDLKPEN Sbjct: 211 QKGIIYRDLKPEN 223
>KS6B1_MOUSE (Q8BSK8) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 60.5 bits (145), Expect = 2e-09 Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 RVLG+G G VF V +A+KV + E ++L + H Sbjct: 95 RVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKA--ERNILEEVKH 152 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L+ +T L + Y +GG+L + + + +F FY AE+ AL LH Sbjct: 153 PFIVDLIYAFQTGGKLYLILEYLSGGEL--FMQLEREGIFMEDTACFYLAEISMALGHLH 210 Query: 388 AAGIAYRDLKPEN 426 GI YRDLKPEN Sbjct: 211 QKGIIYRDLKPEN 223
>KS6B1_HUMAN (P23443) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (p70-alpha) Length = 525 Score = 60.5 bits (145), Expect = 2e-09 Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 RVLG+G G VF V +A+KV + E ++L + H Sbjct: 95 RVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKA--ERNILEEVKH 152 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L+ +T L + Y +GG+L + + + +F FY AE+ AL LH Sbjct: 153 PFIVDLIYAFQTGGKLYLILEYLSGGEL--FMQLEREGIFMEDTACFYLAEISMALGHLH 210 Query: 388 AAGIAYRDLKPEN 426 GI YRDLKPEN Sbjct: 211 QKGIIYRDLKPEN 223
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 60.5 bits (145), Expect = 2e-09 Identities = 43/130 (33%), Positives = 65/130 (50%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G+ G V V YALK R+S+ E +VL+R+ P + Sbjct: 351 KVIGKGSFGKVMQVRKKDTQKVYALKAI-RKSYIVSKSEVTHTLA--ERTVLARVDCPFI 407 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L ++P+ L + + + GG+L Q + F + RFY AEL+ AL +LH Sbjct: 408 VPLKFSFQSPEKLYFVLAFINGGEL--FYHLQKEGRFDLSRARFYTAELLCALDNLHKLD 465 Query: 397 IAYRDLKPEN 426 + YRDLKPEN Sbjct: 466 VVYRDLKPEN 475
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 60.5 bits (145), Expect = 2e-09 Identities = 47/130 (36%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAA---DAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R LG G+ G V LV + YA+KV ++ E +L + HP L Sbjct: 74 RTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTND---ERRMLKLVEHPFL 130 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + G + + M Y GG+L L R + R +P A +FYAAE++ AL LHA Sbjct: 131 IRMWGTFQDARNIFMVMDYIEGGELFSLLR-KSQRFPNPVA-KFYAAEVILALEYLHAHN 188 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 189 IIYRDLKPEN 198
>PCK1_SCHPO (P36582) Protein kinase C-like 1 (EC 2.7.11.13)| Length = 988 Score = 59.7 bits (143), Expect = 3e-09 Identities = 44/130 (33%), Positives = 58/130 (44%), Gaps = 4/130 (3%) Frame = +1 Query: 49 VLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLG+G G V L YA+KV + + V ++ HP L Sbjct: 669 VLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHVFEVANKEKHPFLL 728 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLN-ELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L +T + + M Y GGDL ++R Q FS RFY AE+ AL H G Sbjct: 729 NLFASFQTSTRVYFVMEYILGGDLMVHIQRQQ----FSVKRARFYGAEVCLALKYFHENG 784 Query: 397 IAYRDLKPEN 426 IAYRDLK +N Sbjct: 785 IAYRDLKLDN 794
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 59.3 bits (142), Expect = 4e-09 Identities = 45/130 (34%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R LG G+ G V L+ ++ YALK + + E +LS ++HP + Sbjct: 92 RTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTND---ERRMLSIVSHPFI 148 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + G + + M Y GG+L L R + R +P A +FYAAE+ AL LH+ Sbjct: 149 IRMWGTFQDSQQVFMVMDYIEGGELFSLLR-KSQRFPNPVA-KFYAAEVCLALEYLHSKD 206 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 207 IIYRDLKPEN 216
>ARBK1_RAT (P26817) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 58.9 bits (141), Expect = 5e-09 Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVF---LVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R++GRG G V+ YA+K D++ +S++S P + Sbjct: 195 RIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFI 254 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + TPD L++ + GGDL+ VFS A +RFYAAE++ L +H Sbjct: 255 VCMSYAFHTPDKLSFILDLMNGGDLHY--HLSQHGVFSEADMRFYAAEIILGLEHMHNRF 312 Query: 397 IAYRDLKPEN 426 + YRDLKP N Sbjct: 313 VVYRDLKPAN 322
>ARBK1_MOUSE (Q99MK8) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 58.9 bits (141), Expect = 5e-09 Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVF---LVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R++GRG G V+ YA+K D++ +S++S P + Sbjct: 195 RIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFI 254 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + TPD L++ + GGDL+ VFS A +RFYAAE++ L +H Sbjct: 255 VCMSYAFHTPDKLSFILDLMNGGDLHY--HLSQHGVFSEADMRFYAAEIILGLEHMHNRF 312 Query: 397 IAYRDLKPEN 426 + YRDLKP N Sbjct: 313 VVYRDLKPAN 322
>ARBK1_BOVIN (P21146) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 58.9 bits (141), Expect = 5e-09 Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVF---LVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R++GRG G V+ YA+K D++ +S++S P + Sbjct: 195 RIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFI 254 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + TPD L++ + GGDL+ VFS A +RFYAAE++ L +H Sbjct: 255 VCMSYAFHTPDKLSFILDLMNGGDLHY--HLSQHGVFSEADMRFYAAEIILGLEHMHNRF 312 Query: 397 IAYRDLKPEN 426 + YRDLKP N Sbjct: 313 VVYRDLKPAN 322
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 58.5 bits (140), Expect = 6e-09 Identities = 38/130 (29%), Positives = 61/130 (46%), Gaps = 4/130 (3%) Frame = +1 Query: 49 VLGRGAMGTVFL----VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++G GA VF D E A+K ++++ A E+ +L L H ++ Sbjct: 21 LIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGK-----EIKILKELKHENI 75 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L E + + M YC GGDL + A R S +R + ++ A+ LH+ G Sbjct: 76 VALYDFQEMANSVYLVMEYCNGGDLADYLHAM--RTLSEDTIRLFLQQIAGAMRLLHSKG 133 Query: 397 IAYRDLKPEN 426 I +RDLKP+N Sbjct: 134 IIHRDLKPQN 143
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 58.2 bits (139), Expect = 8e-09 Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 3/144 (2%) Frame = +1 Query: 4 TGVMDIDLPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXX 174 +GV+ ID +V+G+GA G V+ V YA+KV R+ H Sbjct: 126 SGVVGID--DFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVM-RKDHIMEKNHAEYMKA- 181 Query: 175 WEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYA 354 E +L+++ HP + L +T L + + GG L + +F R Y Sbjct: 182 -ERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHL--FFQLYHQGLFREDLARVYT 238 Query: 355 AELVSALADLHAAGIAYRDLKPEN 426 AE+VSA++ LH GI +RDLKPEN Sbjct: 239 AEIVSAVSHLHEKGIMHRDLKPEN 262
>ARBK1_HUMAN (P25098) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein coupled receptor kinase 2) Length = 689 Score = 58.2 bits (139), Expect = 8e-09 Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R++GRG G V+ YA+K D++ +S++S P + Sbjct: 195 RIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFI 254 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + TPD L++ + GGDL+ VFS A +RFYAAE++ L +H Sbjct: 255 VCMSYAFHTPDKLSFILDLMNGGDLHY--HLSQHGVFSEADMRFYAAEIILGLEHMHNRF 312 Query: 397 IAYRDLKPEN 426 + YRDLKP N Sbjct: 313 VVYRDLKPAN 322
>ULK2_MOUSE (Q9QY01) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2) Length = 1037 Score = 57.8 bits (138), Expect = 1e-08 Identities = 37/130 (28%), Positives = 64/130 (49%), Gaps = 4/130 (3%) Frame = +1 Query: 49 VLGRGAMGTVFL----VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++G GA VF D E A+K ++++ + E+ +L L H ++ Sbjct: 14 LVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGK-----EIKILKELQHENI 68 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L E P+ + M YC GGDL + +A+ S +R + ++ +A+ LH+ G Sbjct: 69 VALYDVQELPNSVFLVMEYCNGGDLADYLQAK--GTLSEDTIRVFLHQIAAAMRILHSKG 126 Query: 397 IAYRDLKPEN 426 I +RDLKP+N Sbjct: 127 IIHRDLKPQN 136
>ULK2_HUMAN (Q8IYT8) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) Length = 1036 Score = 57.8 bits (138), Expect = 1e-08 Identities = 37/130 (28%), Positives = 64/130 (49%), Gaps = 4/130 (3%) Frame = +1 Query: 49 VLGRGAMGTVFL----VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++G GA VF D E A+K ++++ + E+ +L L H ++ Sbjct: 14 LVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGK-----EIKILKELQHENI 68 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L E P+ + M YC GGDL + +A+ S +R + ++ +A+ LH+ G Sbjct: 69 VALYDVQELPNSVFLVMEYCNGGDLADYLQAK--GTLSEDTIRVFLHQIAAAMRILHSKG 126 Query: 397 IAYRDLKPEN 426 I +RDLKP+N Sbjct: 127 IIHRDLKPQN 136
>PSK1_SCHPO (Q12706) Serine/threonine-protein kinase psk1 (EC 2.7.11.22)| Length = 436 Score = 57.8 bits (138), Expect = 1e-08 Identities = 46/132 (34%), Positives = 55/132 (41%), Gaps = 6/132 (4%) Frame = +1 Query: 49 VLGRGAMGTVFLVAAD------AEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHP 210 VLGRG+ G V LV A+ LK A G E +L + HP Sbjct: 96 VLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKN-----ERQILEEVRHP 150 Query: 211 HLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA 390 + L + D L + Y GG+L R+ V FY AEL AL LH Sbjct: 151 FICRLYYAFQDHDRLYLILQYAPGGEL--FSHLAEQRMLPEDVVAFYTAELTLALIHLHK 208 Query: 391 AGIAYRDLKPEN 426 GI YRDLKPEN Sbjct: 209 LGIVYRDLKPEN 220
>PKN3_MYXXA (Q9XBQ0) Serine/threonine-protein kinase pkn3 (EC 2.7.11.1)| Length = 547 Score = 57.8 bits (138), Expect = 1e-08 Identities = 47/135 (34%), Positives = 64/135 (47%), Gaps = 5/135 (3%) Frame = +1 Query: 37 RAARVLGRGAMGTVFL---VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 R ++G G MG VF ++ D LKV H E SRL H Sbjct: 19 RVEALIGEGGMGKVFRARQLSLDKVVVLKVL---RHTLLSDERTVARFQREAKAASRLNH 75 Query: 208 PHLPSLLGRAETPD-LLAWAMPYCAGGDLNE-LRRAQPDRVFSPAAVRFYAAELVSALAD 381 P+ S+L + D L AM Y AG DL++ L R P + V ++++SAL+D Sbjct: 76 PNSISVLDFGQAEDGALFIAMEYVAGQDLHQILSREWP---LNEGRVVRIVSQVLSALSD 132 Query: 382 LHAAGIAYRDLKPEN 426 H AG+ +RDLKPEN Sbjct: 133 AHGAGVIHRDLKPEN 147
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 57.4 bits (137), Expect = 1e-08 Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 4/130 (3%) Frame = +1 Query: 49 VLGRGAMGTVFL----VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 ++G GA VF D E A+K ++++ A E+ +L L H ++ Sbjct: 21 LIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGK-----EIKILKELKHENI 75 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L E + + M YC GGDL + R S VR + ++ A+ LH+ G Sbjct: 76 VALYDFQEMANSVYLVMEYCNGGDLADYLHTM--RTLSEDTVRLFLQQIAGAMRLLHSKG 133 Query: 397 IAYRDLKPEN 426 I +RDLKP+N Sbjct: 134 IIHRDLKPQN 143
>PKN1_RAT (Q63433) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protease-activated kinase 1) (PAK-1) Length = 946 Score = 57.4 bits (137), Expect = 1e-08 Identities = 43/129 (33%), Positives = 60/129 (46%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLGRG G V L + +A+K + ++ ++R HP L Sbjct: 624 VLGRGHFGKVLLSEFHSSGELFAIKALKKGDIVARDEVESLMCEKRILATVTRAGHPFLV 683 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 +L G +TP+ + + M Y AGGDL + D VFS FY+A +V L LH I Sbjct: 684 NLFGCFQTPEHVCFVMEYSAGGDL--MLHIHSD-VFSEPRAGFYSACVVLGLQFLHEHKI 740 Query: 400 AYRDLKPEN 426 YRDLK +N Sbjct: 741 VYRDLKLDN 749
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 57.4 bits (137), Expect = 1e-08 Identities = 45/130 (34%), Positives = 66/130 (50%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAA-DAE--YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G+ G V V D + YALK R+++ E +VL+R+ P + Sbjct: 348 KVIGKGSFGKVMQVRKKDTQKIYALKAL-RKAYIVSKCEVTHTLA--ERTVLARVDCPFI 404 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L ++P+ L + + GG+L Q + FS A RFY AEL+ AL LH Sbjct: 405 VPLKFSFQSPEKLYLVLAFINGGEL--FYHLQHEGRFSLARSRFYIAELLCALDSLHKLD 462 Query: 397 IAYRDLKPEN 426 + YRDLKPEN Sbjct: 463 VIYRDLKPEN 472
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 57.4 bits (137), Expect = 1e-08 Identities = 44/130 (33%), Positives = 59/130 (45%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAA-DAE--YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +++G+G G V+LV D E YA+KV ++ + S P + Sbjct: 270 KLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSAADSPFI 329 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L +TP L Y AGG+L Q F +FY AEL+ AL LH G Sbjct: 330 VALRFSFQTPKDLYLVTDYMAGGEL--FWHLQKSVRFPEERAKFYIAELLLALQALHKRG 387 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 388 IVYRDLKPEN 397
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 57.4 bits (137), Expect = 1e-08 Identities = 45/137 (32%), Positives = 61/137 (44%), Gaps = 3/137 (2%) Frame = +1 Query: 25 LPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLS 195 LP +VLG+G+ G V LV + YA+K + + + S Sbjct: 372 LPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLILAS 431 Query: 196 RLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSAL 375 + P L L +T + L + M Y GGDL + Q + F A RFYA E+V AL Sbjct: 432 QC--PFLCQLFCSFQTNEYLFFVMEYLNGGDL--MHHIQQIKKFDEARTRFYACEIVVAL 487 Query: 376 ADLHAAGIAYRDLKPEN 426 LH I YRDLK +N Sbjct: 488 QFLHTNNIIYRDLKLDN 504
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 57.0 bits (136), Expect = 2e-08 Identities = 45/130 (34%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R LG G+ G V L+ + YA+KV + E +LS + HP + Sbjct: 91 RTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVV---RLKQVEHTNDERLMLSIVTHPFI 147 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + G + + M Y GG+L L R + R +P A +FYAAE+ AL LH+ Sbjct: 148 IRMWGTFQDAQQIFMIMDYIEGGELFSLLR-KSQRFPNPVA-KFYAAEVCLALEYLHSKD 205 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 206 IIYRDLKPEN 215
>PKN1_MOUSE (P70268) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) Length = 946 Score = 57.0 bits (136), Expect = 2e-08 Identities = 43/129 (33%), Positives = 61/129 (47%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLGRG G V L ++ +A+K + ++ ++R HP L Sbjct: 624 VLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLV 683 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 +L G +TP+ + + M Y AGGDL + D VFS FY+A +V L LH I Sbjct: 684 NLFGCFQTPEHVCFVMEYSAGGDL--MLHIHSD-VFSEPRAVFYSACVVLGLQFLHEHKI 740 Query: 400 AYRDLKPEN 426 YRDLK +N Sbjct: 741 VYRDLKLDN 749
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 57.0 bits (136), Expect = 2e-08 Identities = 42/133 (31%), Positives = 58/133 (43%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAA------DAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 RVLG+G G VF V YA+KV + E ++L + H Sbjct: 71 RVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRA--ERNILESVKH 128 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + L +T L + +GG+L + + +F FY AE+ AL LH Sbjct: 129 PFIVELAYAFQTGGKLYLILECLSGGEL--FTHLEREGIFLEDTACFYLAEITLALGHLH 186 Query: 388 AAGIAYRDLKPEN 426 + GI YRDLKPEN Sbjct: 187 SQGIIYRDLKPEN 199
>ARBK2_RAT (P26819) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 56.6 bits (135), Expect = 2e-08 Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVF---LVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R++GRG G V+ YA+K D++ +S++S P + Sbjct: 195 RIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNERIMLSLVSTGDCPFI 254 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + TPD L + + GGD++ VFS +RFYA+E++ L +H Sbjct: 255 VCMTYAFHTPDKLCFILDLMNGGDMHY--HLSQHGVFSEKEMRFYASEIILGLEHMHTCF 312 Query: 397 IAYRDLKPEN 426 + YRDLKP N Sbjct: 313 VVYRDLKPAN 322
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 56.6 bits (135), Expect = 2e-08 Identities = 43/129 (33%), Positives = 60/129 (46%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLG+G G V L +E YA+KV + V +R HP L Sbjct: 688 VLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANRERHPFLV 747 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 +L +T + + M + +GGDL + Q ++ FS +FYAAE+ AL H GI Sbjct: 748 NLHSCFQTETRIYFVMDFVSGGDL--MLHIQQEQ-FSRRRAQFYAAEVCLALKYFHDNGI 804 Query: 400 AYRDLKPEN 426 YRDLK +N Sbjct: 805 IYRDLKLDN 813
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 56.6 bits (135), Expect = 2e-08 Identities = 41/130 (31%), Positives = 58/130 (44%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +VLG+G G V L ++D YA+K+ + E VL HP L Sbjct: 184 KVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLT---ENRVLYACVHPFL 240 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L + + + M + GG+L Q + FS A RFY +E++ AL LH Sbjct: 241 TLLKYSFQAQYHICFVMEFANGGEL--FTHLQRCKTFSEARTRFYGSEIILALGYLHHRN 298 Query: 397 IAYRDLKPEN 426 I YRD+K EN Sbjct: 299 IVYRDMKLEN 308
>KPC1_NEUCR (P87253) Protein kinase C-like (EC 2.7.11.13)| Length = 1142 Score = 56.2 bits (134), Expect = 3e-08 Identities = 46/146 (31%), Positives = 63/146 (43%), Gaps = 4/146 (2%) Frame = +1 Query: 1 GTGVMDIDLPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXX 171 GTG M I L VLG+G G V L YA+KV + Sbjct: 807 GTG-MRIGLDHFNFLAVLGKGNFGKVMLAETKKSRKLYAIKVLKKEFIIENDEVESIRSE 865 Query: 172 XWEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLN-ELRRAQPDRVFSPAAVRF 348 + +R HP L +L +T + + M Y +GGDL ++R +F +F Sbjct: 866 KRVFLIANRERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQRG----MFGTKRAQF 921 Query: 349 YAAELVSALADLHAAGIAYRDLKPEN 426 YAAE+ AL H G+ YRDLK +N Sbjct: 922 YAAEVCLALKYFHENGVIYRDLKLDN 947
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 56.2 bits (134), Expect = 3e-08 Identities = 47/133 (35%), Positives = 59/133 (44%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG GA G VFLV A YA+KV + + V L R A Sbjct: 37 KVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQA- 95 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P L +L +T L + Y +GG++ + F A VR Y E+V AL LH Sbjct: 96 PFLVTLHYAFQTDAKLHLILDYVSGGEM--FTHLYQRQYFKEAEVRVYGGEIVLALEHLH 153 Query: 388 AAGIAYRDLKPEN 426 GI YRDLK EN Sbjct: 154 KLGIIYRDLKLEN 166 Score = 35.4 bits (80), Expect = 0.056 Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%) Frame = +1 Query: 280 GGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA-AGIAYRDLKPEN 426 GG+L L + R+FS + LVSA++ +H AG+ +RDLKPEN Sbjct: 488 GGEL--LEHIRKKRLFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPEN 535
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 56.2 bits (134), Expect = 3e-08 Identities = 47/133 (35%), Positives = 59/133 (44%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG GA G VFLV A YA+KV + + V L R A Sbjct: 37 KVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQA- 95 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P L +L +T L + Y +GG++ + F A VR Y E+V AL LH Sbjct: 96 PFLVTLHYAFQTDAKLHLILDYVSGGEM--FTHLYQRQYFKEAEVRVYGGEIVLALEHLH 153 Query: 388 AAGIAYRDLKPEN 426 GI YRDLK EN Sbjct: 154 KLGIIYRDLKLEN 166 Score = 34.3 bits (77), Expect = 0.13 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 2/111 (1%) Frame = +1 Query: 100 EYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL-AHPHLPSLLGRAETPDLLAWAMPYC 276 E+A+K+ RR A EV+ L +HP++ +L + Sbjct: 436 EFAVKILSRRLEA---------NTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELL 486 Query: 277 AGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA-AGIAYRDLKPEN 426 GG+L L + R FS + LVSA++ +H AG+ +RDLKPEN Sbjct: 487 RGGEL--LEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPEN 535
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 55.8 bits (133), Expect = 4e-08 Identities = 43/130 (33%), Positives = 59/130 (45%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAA-DAE--YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R+LG+G G V+ V D + YA+KV ++ + + + P + Sbjct: 415 RLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFI 474 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +TP L Y +GG+L Q + FS +FY AELV AL LH Sbjct: 475 VGLKFSFQTPTDLYLVTDYMSGGEL--FWHLQKEGRFSEDRAKFYIAELVLALEHLHDND 532 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 533 IVYRDLKPEN 542
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 55.8 bits (133), Expect = 4e-08 Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVF---LVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R++GRG G V+ YA+K D++ +S++S P + Sbjct: 195 RIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFI 254 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + TPD L + + GGDL+ VFS +RFYA E++ L +H Sbjct: 255 VCMTYAFHTPDKLCFILDLMNGGDLHY--HLSQHGVFSEKEMRFYATEIILGLEHMHNRF 312 Query: 397 IAYRDLKPEN 426 + YRDLKP N Sbjct: 313 VVYRDLKPAN 322
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 55.8 bits (133), Expect = 4e-08 Identities = 43/134 (32%), Positives = 56/134 (41%), Gaps = 4/134 (2%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 R RVLG+G G V A YA K +++ E +L ++ Sbjct: 310 RMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLI---EKQILQKINS 366 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLN-ELRRAQPDRVFSPAAVRFYAAELVSALADL 384 P + +L ET D L + GGDL + + F RFYAAE+ L L Sbjct: 367 PFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFELERARFYAAEVACGLQHL 426 Query: 385 HAAGIAYRDLKPEN 426 H GI YRD KPEN Sbjct: 427 HKQGIVYRDCKPEN 440
>GRK7_PIG (Q8WP15) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 55.5 bits (132), Expect = 5e-08 Identities = 41/130 (31%), Positives = 57/130 (43%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 RVLG+G G V V YA K D++ E +L +++ P + Sbjct: 195 RVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKSGEKMALS---EKEILEKVSSPFV 251 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 SL E+ L M GGDL + +R V FY+A++ + LH+ G Sbjct: 252 VSLAYAFESKSHLCLVMSLMNGGDLKFHIYSVGERGLDMNRVIFYSAQMTCGVLHLHSLG 311 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 312 IVYRDLKPEN 321
>ARBK1_MESAU (Q64682) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 55.5 bits (132), Expect = 5e-08 Identities = 39/130 (30%), Positives = 59/130 (45%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVF---LVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R++GRG G V+ YA+K D++ +S++S P + Sbjct: 195 RIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFI 254 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + TPD L++ + GGDL+ VFS A +R YAAE++ L +H Sbjct: 255 VCMSYAFRTPDNLSFILDLMNGGDLHY--HLSQHGVFSEADMRSYAAEIILGLEHMHNRF 312 Query: 397 IAYRDLKPEN 426 + YRDLKP N Sbjct: 313 VVYRDLKPAN 322
>ARBK2_HUMAN (P35626) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 55.5 bits (132), Expect = 5e-08 Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVF---LVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R++GRG G V+ YA+K D++ +S++S P + Sbjct: 195 RIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFI 254 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 + TPD L + + GGDL+ VFS +RFYA E++ L +H Sbjct: 255 VCMTYAFHTPDKLCFILDLMNGGDLHY--HLSQHGVFSEKEMRFYATEIILGLEHVHNRF 312 Query: 397 IAYRDLKPEN 426 + YRDLKP N Sbjct: 313 VVYRDLKPAN 322
>KPCI_MOUSE (Q62074) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) Length = 586 Score = 55.1 bits (131), Expect = 7e-08 Identities = 50/147 (34%), Positives = 64/147 (43%), Gaps = 7/147 (4%) Frame = +1 Query: 7 GVMDIDLPSARAARVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXW 177 G+ D DL RV+GRG+ V LV D YA+KV + W Sbjct: 240 GLQDFDL-----LRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKE------LVNDDEDIDW 288 Query: 178 ---EVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVR 345 E V + + HP L L +T L + + Y GGDL + Q R R Sbjct: 289 VQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDL--MFHMQRQRKLPEEHAR 346 Query: 346 FYAAELVSALADLHAAGIAYRDLKPEN 426 FY+AE+ AL LH GI YRDLK +N Sbjct: 347 FYSAEISLALNYLHERGIIYRDLKLDN 373
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 55.1 bits (131), Expect = 7e-08 Identities = 42/130 (32%), Positives = 54/130 (41%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +VLG+G G V L YA+K+ + E VL R HP L Sbjct: 197 KVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLT---ENRVLQRCKHPFL 253 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L + L + M + GG+L + FS RFY AE+V AL LH Sbjct: 254 TELKYSFQEQHYLCFVMQFANGGEL--FTHVRKCGTFSEPRARFYGAEIVLALGYLHRCD 311 Query: 397 IAYRDLKPEN 426 I YRD+K EN Sbjct: 312 IVYRDMKLEN 321
>KPCI_PONPY (Q5R4K9) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| Length = 587 Score = 55.1 bits (131), Expect = 7e-08 Identities = 50/147 (34%), Positives = 64/147 (43%), Gaps = 7/147 (4%) Frame = +1 Query: 7 GVMDIDLPSARAARVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXW 177 G+ D DL RV+GRG+ V LV D YA+KV + W Sbjct: 241 GLQDFDL-----LRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKE------LVNDDEDIDW 289 Query: 178 ---EVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVR 345 E V + + HP L L +T L + + Y GGDL + Q R R Sbjct: 290 VQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDL--MFHMQRQRKLPEEHAR 347 Query: 346 FYAAELVSALADLHAAGIAYRDLKPEN 426 FY+AE+ AL LH GI YRDLK +N Sbjct: 348 FYSAEISLALNYLHERGIIYRDLKLDN 374
>KPCI_HUMAN (P41743) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota) Length = 587 Score = 55.1 bits (131), Expect = 7e-08 Identities = 50/147 (34%), Positives = 64/147 (43%), Gaps = 7/147 (4%) Frame = +1 Query: 7 GVMDIDLPSARAARVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXW 177 G+ D DL RV+GRG+ V LV D YA+KV + W Sbjct: 241 GLQDFDL-----LRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKE------LVNDDEDIDW 289 Query: 178 ---EVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVR 345 E V + + HP L L +T L + + Y GGDL + Q R R Sbjct: 290 VQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDL--MFHMQRQRKLPEEHAR 347 Query: 346 FYAAELVSALADLHAAGIAYRDLKPEN 426 FY+AE+ AL LH GI YRDLK +N Sbjct: 348 FYSAEISLALNYLHERGIIYRDLKLDN 374
>KPC1_YEAST (P24583) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1151 Score = 54.7 bits (130), Expect = 9e-08 Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAA---DAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +VLG+G G V L + D A+KV + + + ++ HP L Sbjct: 828 KVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFL 887 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L +T + + +AM + GGDL + Q R+ S +FYAAE++ AL H G Sbjct: 888 TNLYCSFQTENRIYFAMEFIGGGDL--MWHVQNQRL-SVRRAKFYAAEVLLALKYFHDNG 944 Query: 397 IAYRDLKPEN 426 + YRDLK EN Sbjct: 945 VIYRDLKLEN 954
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 54.7 bits (130), Expect = 9e-08 Identities = 44/133 (33%), Positives = 54/133 (40%), Gaps = 3/133 (2%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 R RVLG+G G V A YA K +++ E +L ++ Sbjct: 187 RQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALN---EKQILEKVNS 243 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 + SL ET D L + GGDL F A FYAAE+ L DLH Sbjct: 244 RFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLH 303 Query: 388 AAGIAYRDLKPEN 426 I YRDLKPEN Sbjct: 304 RERIVYRDLKPEN 316
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 54.7 bits (130), Expect = 9e-08 Identities = 44/133 (33%), Positives = 54/133 (40%), Gaps = 3/133 (2%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 R RVLG+G G V A YA K +++ E +L ++ Sbjct: 187 RQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALN---EKQILEKVNS 243 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 + SL ET D L + GGDL F A FYAAE+ L DLH Sbjct: 244 RFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLH 303 Query: 388 AAGIAYRDLKPEN 426 I YRDLKPEN Sbjct: 304 RERIVYRDLKPEN 316
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 54.7 bits (130), Expect = 9e-08 Identities = 44/133 (33%), Positives = 54/133 (40%), Gaps = 3/133 (2%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 R RVLG+G G V A YA K +++ E +L ++ Sbjct: 187 RQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALN---EKQILEKVNS 243 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 + SL ET D L + GGDL F A FYAAE+ L DLH Sbjct: 244 RFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLH 303 Query: 388 AAGIAYRDLKPEN 426 I YRDLKPEN Sbjct: 304 RERIVYRDLKPEN 316
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 54.7 bits (130), Expect = 9e-08 Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 3/131 (2%) Frame = +1 Query: 43 ARVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPH 213 A+ LG GA G V L+ A+K+ D + H EV + L H Sbjct: 25 AQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRK-----EVCIQKMLQDKH 79 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 + G+ + + Y AGG+L + R +PD + Y +L+S L LH Sbjct: 80 ILRFFGKRSQGSVEYIFLEYAAGGELFD--RIEPDVGMPQHEAQRYFTQLLSGLNYLHQR 137 Query: 394 GIAYRDLKPEN 426 GIA+RDLKPEN Sbjct: 138 GIAHRDLKPEN 148
>KPC1_TRIRE (Q99014) Protein kinase C-like (EC 2.7.11.13)| Length = 1139 Score = 54.7 bits (130), Expect = 9e-08 Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 4/146 (2%) Frame = +1 Query: 1 GTGVMDIDLPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXX 171 GTG I L VLG+G G V L +A+KV + Sbjct: 804 GTGAR-IGLDHFNFLAVLGKGNFGKVMLAETKRSKRLFAIKVLKKEFIIENDEVESIKSE 862 Query: 172 XWEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLN-ELRRAQPDRVFSPAAVRF 348 + +R HP L +L +T + + M Y +GGDL ++R Q F +F Sbjct: 863 KRVFLIANRERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQRGQ----FGTKRAQF 918 Query: 349 YAAELVSALADLHAAGIAYRDLKPEN 426 YAAE+ AL H G+ YRDLK +N Sbjct: 919 YAAEVCLALKYFHENGVIYRDLKLDN 944
>PKAB_STRCO (P54740) Serine/threonine protein kinase pkaB (EC 2.7.11.1)| Length = 417 Score = 54.7 bits (130), Expect = 9e-08 Identities = 44/130 (33%), Positives = 61/130 (46%), Gaps = 1/130 (0%) Frame = +1 Query: 40 AARVLGRGAMGTVFL-VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 A ++LGRG+ GTV+L D A+K+ R A E + L L HPH+ Sbjct: 11 AHQILGRGSAGTVWLGEGPDGPVAIKLL-REDLASDQELVSRFVQ--ERTALLGLDHPHV 67 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 S+ + LA M G DL R +R +P A A++ LA HAAG Sbjct: 68 VSVRDLVVDGNDLALVMDLVRGTDLRT--RLDRERRLAPEAAVAVVADVADGLAAAHAAG 125 Query: 397 IAYRDLKPEN 426 + +RD+KPEN Sbjct: 126 VVHRDVKPEN 135
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 54.7 bits (130), Expect = 9e-08 Identities = 40/127 (31%), Positives = 58/127 (45%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPSL 225 R+LG+G+ G V + A D E K ++ + EV++L + H H+ L Sbjct: 120 RILGKGSFGIV-IEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHL 178 Query: 226 LGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAY 405 ETP + M C G+L E+ + FS R+ L SA+A LH I + Sbjct: 179 EQVFETPKKMYLVMELCEDGELKEILDRKGH--FSENETRWIIQSLASAIAYLHNNDIVH 236 Query: 406 RDLKPEN 426 RDLK EN Sbjct: 237 RDLKLEN 243
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 54.7 bits (130), Expect = 9e-08 Identities = 37/127 (29%), Positives = 60/127 (47%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPSL 225 RVLGRGA G L + +L V+ + E+ +L+ L H ++ + Sbjct: 56 RVLGRGAFGEATLYRRTEDDSLVVW-KEVDLTRLSEKERRDALNEIVILALLQHDNIIAY 114 Query: 226 LGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAY 405 L + YC GG+L + Q D++F V +Y ++VSA++ +H AGI + Sbjct: 115 YNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILH 174 Query: 406 RDLKPEN 426 RD+K N Sbjct: 175 RDIKTLN 181
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 54.7 bits (130), Expect = 9e-08 Identities = 37/127 (29%), Positives = 60/127 (47%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPSL 225 RVLGRGA G L + +L V+ + E+ +L+ L H ++ + Sbjct: 56 RVLGRGAFGEATLYRRTEDDSLVVW-KEVDLTRLSEKERRDALNEIVILALLQHDNIIAY 114 Query: 226 LGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAY 405 L + YC GG+L + Q D++F V +Y ++VSA++ +H AGI + Sbjct: 115 YNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILH 174 Query: 406 RDLKPEN 426 RD+K N Sbjct: 175 RDIKTLN 181
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 54.7 bits (130), Expect = 9e-08 Identities = 32/83 (38%), Positives = 47/83 (56%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E+ L L H H+ L ET + + + YC GG+L + +Q DR+ S R Sbjct: 57 EIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQ-DRL-SEEETRVVFR 114 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 ++VSA+A +H+ G A+RDLKPEN Sbjct: 115 QIVSAVAYVHSQGYAHRDLKPEN 137
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 54.7 bits (130), Expect = 9e-08 Identities = 45/149 (30%), Positives = 70/149 (46%), Gaps = 8/149 (5%) Frame = +1 Query: 4 TGVMDIDLPSARAARVLGRGAMGTVFLVA---ADAEYALKVFDR-----RSHAPGXXXXX 159 +GV+ I+ +V+G+GA G V+ V YA+KV + ++HA Sbjct: 132 SGVVGIE--DFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKA-- 187 Query: 160 XXXXXWEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAA 339 E +L+++ HP + L +T L + + GG L + +F Sbjct: 188 ------ERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHL--FFQLYHQGLFREDL 239 Query: 340 VRFYAAELVSALADLHAAGIAYRDLKPEN 426 R Y AE+VSA++ LH GI +RDLKPEN Sbjct: 240 ARVYTAEIVSAVSHLHEKGIMHRDLKPEN 268
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 54.7 bits (130), Expect = 9e-08 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV A + YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN---EKRILQAVEFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 54.7 bits (130), Expect = 9e-08 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV A + YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN---EKRILQAVEFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 54.7 bits (130), Expect = 9e-08 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV A + YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN---EKRILQAVEFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>SSK2_YEAST (P53599) MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of| sensor kinase 2) Length = 1579 Score = 54.7 bits (130), Expect = 9e-08 Identities = 32/83 (38%), Positives = 44/83 (53%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E+SVL L HP++ S G D + M YC GG L L + R+ + Y Sbjct: 1315 EMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAAL--LEHGRIEDEMVTQVYTL 1372 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 +L+ LA LH +GI +RD+KPEN Sbjct: 1373 QLLEGLAYLHESGIVHRDVKPEN 1395
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 54.7 bits (130), Expect = 9e-08 Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 3/144 (2%) Frame = +1 Query: 4 TGVMDIDLPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXX 174 TG + L + LG+G G V+LV ALK +++ G Sbjct: 89 TGFRNYSLDDFEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGNVEKQFRR-- 146 Query: 175 WEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYA 354 EV + S L H ++ L G D + + Y G+L +L R Q + F+ + Y Sbjct: 147 -EVEIQSNLRHTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQ--KRFTESTASSYI 203 Query: 355 AELVSALADLHAAGIAYRDLKPEN 426 ++ AL LH I +RD+KPEN Sbjct: 204 YQMSEALLYLHGKNIIHRDIKPEN 227
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 54.3 bits (129), Expect = 1e-07 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV A + YA+K+ D++ E +L + P L Sbjct: 94 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 150 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 151 VRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 207 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 208 DLIYRDLKPEN 218
>KPCZ_RAT (P09217) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 54.3 bits (129), Expect = 1e-07 Identities = 51/149 (34%), Positives = 64/149 (42%), Gaps = 7/149 (4%) Frame = +1 Query: 1 GTGVMDIDLPSARAARVLGRGAMGTVFLVAA---DAEYALKVFDRRSHAPGXXXXXXXXX 171 G G+ D DL RV+GRG+ V LV D YA+KV + Sbjct: 246 GLGLQDFDL-----IRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKE------LVHDDEDI 294 Query: 172 XW---EVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAA 339 W E V + + +P L L +T L + Y GGDL + Q R Sbjct: 295 DWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDL--MFHMQRQRKLPEEH 352 Query: 340 VRFYAAELVSALADLHAAGIAYRDLKPEN 426 RFYAAE+ AL LH GI YRDLK +N Sbjct: 353 ARFYAAEICIALNFLHERGIIYRDLKLDN 381
>KPCZ_MOUSE (Q02956) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 54.3 bits (129), Expect = 1e-07 Identities = 51/149 (34%), Positives = 64/149 (42%), Gaps = 7/149 (4%) Frame = +1 Query: 1 GTGVMDIDLPSARAARVLGRGAMGTVFLVAA---DAEYALKVFDRRSHAPGXXXXXXXXX 171 G G+ D DL RV+GRG+ V LV D YA+KV + Sbjct: 246 GLGLQDFDL-----IRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKE------LVHDDEDI 294 Query: 172 XW---EVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAA 339 W E V + + +P L L +T L + Y GGDL + Q R Sbjct: 295 DWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDL--MFHMQRQRKLPEEH 352 Query: 340 VRFYAAELVSALADLHAAGIAYRDLKPEN 426 RFYAAE+ AL LH GI YRDLK +N Sbjct: 353 ARFYAAEICIALNFLHERGIIYRDLKLDN 381
>KPCZ_HUMAN (Q05513) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 54.3 bits (129), Expect = 1e-07 Identities = 51/149 (34%), Positives = 64/149 (42%), Gaps = 7/149 (4%) Frame = +1 Query: 1 GTGVMDIDLPSARAARVLGRGAMGTVFLVAA---DAEYALKVFDRRSHAPGXXXXXXXXX 171 G G+ D DL RV+GRG+ V LV D YA+KV + Sbjct: 246 GLGLQDFDL-----IRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKE------LVHDDEDI 294 Query: 172 XW---EVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAA 339 W E V + + +P L L +T L + Y GGDL + Q R Sbjct: 295 DWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDL--MFHMQRQRKLPEEH 352 Query: 340 VRFYAAELVSALADLHAAGIAYRDLKPEN 426 RFYAAE+ AL LH GI YRDLK +N Sbjct: 353 ARFYAAEICIALNFLHERGIIYRDLKLDN 381
>GAD8_SCHPO (Q9P7J8) Serine/threonine-protein kinase gad8 (EC 2.7.11.1)| Length = 569 Score = 54.3 bits (129), Expect = 1e-07 Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G+ G V V YALK +++H E +VL+++ +P + Sbjct: 234 KVVGKGSFGKVMQVRKRDTSRIYALKTM-KKAHIVSRSEVDHTLA--ERTVLAQVNNPFI 290 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L ++P L + + GG+L Q + F +FY AEL+ AL LH Sbjct: 291 VPLKFSFQSPGKLYLVLAFVNGGEL--FHHLQREGCFDTYRAKFYIAELLVALECLHEFN 348 Query: 397 IAYRDLKPEN 426 + YRDLKPEN Sbjct: 349 VIYRDLKPEN 358
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 54.3 bits (129), Expect = 1e-07 Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 9/135 (6%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSR--LAHPH 213 VLG+G+ G V L D YA+K+ + E +++ + LA P Sbjct: 325 VLGKGSFGKVVLAERKGTDELYAIKILKK--------DVIIQDDDVECTMIEKRVLALPD 376 Query: 214 LPSLLGRA----ETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALAD 381 P L + +T D L + M Y GGDL + R Q + F FYAAE+ L Sbjct: 377 KPPFLVQLHSCFQTMDRLYFVMEYVNGGDL--MYRIQQEGKFKEPVAAFYAAEIAIGLFY 434 Query: 382 LHAAGIAYRDLKPEN 426 LH GI YRDLK +N Sbjct: 435 LHTQGIVYRDLKLDN 449
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 54.3 bits (129), Expect = 1e-07 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV A + YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 54.3 bits (129), Expect = 1e-07 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV A + YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 54.3 bits (129), Expect = 1e-07 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV + YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y AGG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 54.3 bits (129), Expect = 1e-07 Identities = 43/131 (32%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV A + YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 54.3 bits (129), Expect = 1e-07 Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 6/132 (4%) Frame = +1 Query: 49 VLGRGAMGTVFLVAA------DAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHP 210 VLG+G G VF V YA+KV + E ++L + HP Sbjct: 72 VLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRA--ERNILESVKHP 129 Query: 211 HLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA 390 + L +T L + +GG+L + + +F FY AE+ AL LH+ Sbjct: 130 FIVELAYAFQTGGKLYLILECLSGGEL--FTHLEREGIFLEDTACFYLAEITLALGHLHS 187 Query: 391 AGIAYRDLKPEN 426 GI YRDLKPEN Sbjct: 188 HGIIYRDLKPEN 199
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 54.3 bits (129), Expect = 1e-07 Identities = 32/74 (43%), Positives = 39/74 (52%) Frame = +1 Query: 205 HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADL 384 HP+L L +T L + M Y GGDL + Q FS RFY AE++S L L Sbjct: 373 HPYLCHLFCTFQTESHLFFVMEYLNGGDL--MFHIQESGRFSEERARFYGAEIISGLKFL 430 Query: 385 HAAGIAYRDLKPEN 426 H GI YRDLK +N Sbjct: 431 HKKGIIYRDLKLDN 444
>KPC1_ASPNG (Q00078) Protein kinase C-like (EC 2.7.11.13)| Length = 1096 Score = 54.3 bits (129), Expect = 1e-07 Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 4/130 (3%) Frame = +1 Query: 49 VLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLG+G G V L + YA+KV + + ++ HP L Sbjct: 776 VLGKGNFGKVMLAETKSTKRLYAIKVLKKEFIIENDEVESTKSEKRVFMIANKERHPFLL 835 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLN-ELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L +T + + M Y +GGDL ++R Q F +FYAAE++ AL H G Sbjct: 836 NLHACFQTETRVYFVMEYISGGDLMLHIQRGQ----FGLKRAQFYAAEVLLALKYFHENG 891 Query: 397 IAYRDLKPEN 426 + YRDLK +N Sbjct: 892 VIYRDLKLDN 901
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 53.9 bits (128), Expect = 2e-07 Identities = 49/147 (33%), Positives = 65/147 (44%), Gaps = 7/147 (4%) Frame = +1 Query: 7 GVMDIDLPSARAARVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXW 177 G++D DL RV+GRG+ V LV + YA+KV + W Sbjct: 242 GLIDFDL-----LRVIGRGSYAKVLLVRLKKTERIYAMKVVKKE------LVNDDEDIDW 290 Query: 178 ---EVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVR 345 E V + + HP L L +T L + + Y GGDL + Q R R Sbjct: 291 VQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDL--MFHMQRQRKLPEEHAR 348 Query: 346 FYAAELVSALADLHAAGIAYRDLKPEN 426 FY+AE+ AL LH GI YRDLK +N Sbjct: 349 FYSAEISLALNYLHERGIIYRDLKLDN 375
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 53.9 bits (128), Expect = 2e-07 Identities = 41/128 (32%), Positives = 58/128 (45%), Gaps = 3/128 (2%) Frame = +1 Query: 52 LGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPS 222 LGRGA V+ YALKV + E+ VL RL+HP++ Sbjct: 48 LGRGATSIVYRCKQKGTQKPYALKVLKK--------TVDKKIVRTEIGVLLRLSHPNIIK 99 Query: 223 LLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIA 402 L ETP ++ + GG+L + R +S R +++ A+A LH GI Sbjct: 100 LKEIFETPTEISLVLELVTGGELFD--RIVEKGYYSERDARDAVKQILEAVAYLHENGIV 157 Query: 403 YRDLKPEN 426 +RDLKPEN Sbjct: 158 HRDLKPEN 165
>PKN1_HUMAN (Q16512) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha) Length = 942 Score = 53.9 bits (128), Expect = 2e-07 Identities = 42/129 (32%), Positives = 59/129 (45%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLGRG G V L + +A+K + ++ ++ HP L Sbjct: 620 VLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLV 679 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 +L G +TP+ + + M Y AGGDL + D VFS FY+A +V L LH I Sbjct: 680 NLFGCFQTPEHVCFVMEYSAGGDL--MLHIHSD-VFSEPRAIFYSACVVLGLQFLHEHKI 736 Query: 400 AYRDLKPEN 426 YRDLK +N Sbjct: 737 VYRDLKLDN 745
>KPC1_COCHE (O42632) Protein kinase C-like (EC 2.7.11.13)| Length = 1174 Score = 53.9 bits (128), Expect = 2e-07 Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 4/146 (2%) Frame = +1 Query: 1 GTGVMDIDLPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXX 171 GTG I L VLG+G G V L YA+KV + Sbjct: 839 GTGKR-IGLDHFNFLAVLGKGNFGKVMLAETKTTKQLYAIKVLKKEFIIENDEVESTRSE 897 Query: 172 XWEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLN-ELRRAQPDRVFSPAAVRF 348 + ++ HP L +L +T + + M Y +GGDL ++R Q F +F Sbjct: 898 KRVFLIANKERHPFLLNLHACFQTETRVYFVMEYISGGDLMLHIQRGQ----FGTKRAQF 953 Query: 349 YAAELVSALADLHAAGIAYRDLKPEN 426 YAAE+ AL H G+ YRDLK +N Sbjct: 954 YAAEVCLALKYFHENGVIYRDLKLDN 979
>PRKY_HUMAN (O43930) Serine/threonine-protein kinase PRKY (EC 2.7.11.1)| Length = 277 Score = 53.9 bits (128), Expect = 2e-07 Identities = 48/142 (33%), Positives = 59/142 (41%), Gaps = 8/142 (5%) Frame = +1 Query: 25 LPSARAARVLGRGAMGTVFLV---AADAEYALKVFD-----RRSHAPGXXXXXXXXXXWE 180 L A +G G G V LV A +ALKV RR E Sbjct: 46 LQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHN--------E 97 Query: 181 VSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAE 360 SVL ++HP L L L M Y GG+L R + FS FY+AE Sbjct: 98 KSVLKEVSHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGH--FSSTTGLFYSAE 155 Query: 361 LVSALADLHAAGIAYRDLKPEN 426 ++ A+ LH+ I YRDLKPEN Sbjct: 156 IICAIEYLHSKEIVYRDLKPEN 177
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 53.9 bits (128), Expect = 2e-07 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 3/131 (2%) Frame = +1 Query: 43 ARVLGRGAMGTV---FLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPH 213 +R LG G+ V V + A+KV D++ ++ + R HP+ Sbjct: 65 SRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR--HPN 122 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 + LL ET + M C GG+L + + + A R Y +L+SA+ LH A Sbjct: 123 ITQLLDILETENSYYLVMELCPGGNL--MHKIYEKKRLDEAEARRYIRQLISAVEHLHRA 180 Query: 394 GIAYRDLKPEN 426 G+ +RDLK EN Sbjct: 181 GVVHRDLKIEN 191
>PKD1_DICDI (P34100) Developmentally-regulated protein kinase 1 (EC 2.7.11.1)| (Fragment) Length = 416 Score = 53.5 bits (127), Expect = 2e-07 Identities = 28/83 (33%), Positives = 44/83 (53%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E++++ ++HP++ TP + + M Y DL RA ++ F+ + A Sbjct: 84 EINIMLNISHPYIVKTYSTFNTPTKIHFIMEYAGKKDLFHHLRA--NKCFTEQTTKLIVA 141 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 E+V A+ LHA I YRDLKPEN Sbjct: 142 EIVLAIEYLHAENIIYRDLKPEN 164
>KDC1_DROME (P16911) Protein kinase DC1 (EC 2.7.11.1)| Length = 376 Score = 53.5 bits (127), Expect = 2e-07 Identities = 43/129 (33%), Positives = 57/129 (44%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLG G+ GTV LV + YA K+ + E VL+ P L Sbjct: 50 VLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLV---RLKQVAHVHNEKHVLNAARFPFLI 106 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L+ + D L +P GG+L R R F+ RFYAA++ AL +H + Sbjct: 107 YLVDSTKCFDYLYLILPLVNGGELFSYHRRV--RKFNEKHARFYAAQVALALEYMHKMHL 164 Query: 400 AYRDLKPEN 426 YRDLKPEN Sbjct: 165 MYRDLKPEN 173
>KBN8_YEAST (P38070) Probable serine/threonine-protein kinase YBR028C (EC| 2.7.11.1) Length = 525 Score = 53.5 bits (127), Expect = 2e-07 Identities = 31/83 (37%), Positives = 40/83 (48%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E S+LS + HP++ L L + Y GG+L + V FYAA Sbjct: 202 ERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGEL--FYHLKEHGTLDETTVSFYAA 259 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 E+ AL LH G+ YRDLKPEN Sbjct: 260 EISCALRFLHTKGVVYRDLKPEN 282
>PKN2_HUMAN (Q16513) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 984 Score = 53.5 bits (127), Expect = 2e-07 Identities = 43/138 (31%), Positives = 59/138 (42%), Gaps = 3/138 (2%) Frame = +1 Query: 22 DLPSARAARVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVL 192 +L R VLGRG G V L + +A+K + + Sbjct: 653 NLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETV 712 Query: 193 SRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSA 372 + + HP L +L +T + + + M Y AGGDL + D P AV FYAA +V Sbjct: 713 NSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MMHIHTDVFSEPRAV-FYAACVVLG 769 Query: 373 LADLHAAGIAYRDLKPEN 426 L LH I YRDLK +N Sbjct: 770 LQYLHEHKIVYRDLKLDN 787
>PKN2_RAT (O08874) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) (Protease-activated kinase 2) (PAK-2) (Fragment) Length = 842 Score = 53.5 bits (127), Expect = 2e-07 Identities = 43/138 (31%), Positives = 59/138 (42%), Gaps = 3/138 (2%) Frame = +1 Query: 22 DLPSARAARVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVL 192 +L R VLGRG G V L + +A+K + + Sbjct: 517 NLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETV 576 Query: 193 SRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSA 372 + + HP L +L +T + + + M Y AGGDL + D P AV FYAA +V Sbjct: 577 NSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MMHIHTDVFSEPRAV-FYAACVVLG 633 Query: 373 LADLHAAGIAYRDLKPEN 426 L LH I YRDLK +N Sbjct: 634 LQYLHEHKIVYRDLKLDN 651
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 53.5 bits (127), Expect = 2e-07 Identities = 35/84 (41%), Positives = 44/84 (52%), Gaps = 1/84 (1%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYA 354 E ++L + HP + SL + L Y GG+L LR A F+ FYA Sbjct: 322 ERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGK---FTSQTSNFYA 378 Query: 355 AELVSALADLHAAGIAYRDLKPEN 426 AE+VSAL LH+ I YRDLKPEN Sbjct: 379 AEIVSALEYLHSLQIVYRDLKPEN 402
>STK35_HUMAN (Q8TDR2) Serine/threonine-protein kinase 35 (EC 2.7.11.1)| (CLP-36-interacting kinase) (Clik1) (PDLIM1-interacting kinase 1) Length = 401 Score = 53.1 bits (126), Expect = 3e-07 Identities = 30/69 (43%), Positives = 42/69 (60%), Gaps = 1/69 (1%) Frame = +1 Query: 223 LLGRAETPDLLAWAMPYCAGGDLNE-LRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 +LG AE P L + M +C GGDLN+ + +PD PA + + +L SA+A LH I Sbjct: 168 ILGYAEEPCYLWFVMEFCEGGDLNQYVLSRRPD----PATNKSFMLQLTSAIAFLHKNHI 223 Query: 400 AYRDLKPEN 426 +RDLKP+N Sbjct: 224 VHRDLKPDN 232
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 53.1 bits (126), Expect = 3e-07 Identities = 34/83 (40%), Positives = 42/83 (50%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E +VL + HP L LL L M + GG+L R + FS A FYA Sbjct: 94 EKAVLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGR--FSSVASVFYAT 151 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 E+V A+ LH+ I YRDLKPEN Sbjct: 152 EIVCAIEYLHSKEIVYRDLKPEN 174
>PKN2_MOUSE (Q8BWW9) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 983 Score = 53.1 bits (126), Expect = 3e-07 Identities = 43/137 (31%), Positives = 58/137 (42%), Gaps = 3/137 (2%) Frame = +1 Query: 25 LPSARAARVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLS 195 L R VLGRG G V L + +A+K + ++ Sbjct: 653 LQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 712 Query: 196 RLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSAL 375 + HP L +L +T + + + M Y AGGDL + D P AV FYAA +V L Sbjct: 713 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDL--MMHIHTDVFSEPRAV-FYAACVVLGL 769 Query: 376 ADLHAAGIAYRDLKPEN 426 LH I YRDLK +N Sbjct: 770 QYLHEHKIVYRDLKLDN 786
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 53.1 bits (126), Expect = 3e-07 Identities = 47/143 (32%), Positives = 63/143 (44%), Gaps = 7/143 (4%) Frame = +1 Query: 19 IDLPSARAARVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWE 180 + L + RVLG GA G VFLV A YA+KV ++ + E Sbjct: 256 VSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKT--E 313 Query: 181 VSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 VL + +P L SL ++ L + + GG+L F + VR Y A Sbjct: 314 RVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGEL--FTHLYHSENFEESRVRVYIA 371 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 E+V AL LH GI YRD+K EN Sbjct: 372 EVVLALEQLHQLGIIYRDIKLEN 394
>GRK4_MOUSE (O70291) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 574 Score = 53.1 bits (126), Expect = 3e-07 Identities = 45/133 (33%), Positives = 53/133 (39%), Gaps = 3/133 (2%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 R RVLG+G G V A YA K +++ E +L +L Sbjct: 187 RQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALN---EKRILEKLHS 243 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 + SL ET D L + GGDL D F FYAAEL L DL Sbjct: 244 RFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGDPGFEEPRAVFYAAELCCGLEDLQ 303 Query: 388 AAGIAYRDLKPEN 426 I YRDLKPEN Sbjct: 304 RKRIVYRDLKPEN 316
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 53.1 bits (126), Expect = 3e-07 Identities = 39/128 (30%), Positives = 59/128 (46%), Gaps = 3/128 (2%) Frame = +1 Query: 52 LGRGAMGTVFL---VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPS 222 LGRGA V+L YA+KV ++ EV +L ++ HP++ + Sbjct: 14 LGRGAFSIVYLGENKQTKQRYAIKVINKSE----LGKDYEKNLKMEVDILKKVNHPNIIA 69 Query: 223 LLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIA 402 L +TP+ L M GG+L + + +S A ++VSA+ LH I Sbjct: 70 LKELFDTPEKLYLVMELVTGGELFD--KIVEKGSYSEADAANLVKKIVSAVGYLHGLNIV 127 Query: 403 YRDLKPEN 426 +RDLKPEN Sbjct: 128 HRDLKPEN 135
>GRK5_BOVIN (P43249) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 53.1 bits (126), Expect = 3e-07 Identities = 40/130 (30%), Positives = 51/130 (39%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R RVLG+G G V A + R E +L ++ + Sbjct: 187 RQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSRFV 246 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L ET D L + GGDL + F FYAAE++ L DLH Sbjct: 247 VNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHHEN 306 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 307 IVYRDLKPEN 316
>SSK22_YEAST (P25390) Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP| kinase kinase kinase SSK22) (Suppressor of sensor kinase 22) Length = 1331 Score = 53.1 bits (126), Expect = 3e-07 Identities = 30/83 (36%), Positives = 42/83 (50%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E++VL L HP++ G D + M YC GG L L R+ + Y Sbjct: 1083 EMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASL--LDHGRIEDEMVTQVYTF 1140 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 EL+ LA LH +G+ +RD+KPEN Sbjct: 1141 ELLEGLAYLHQSGVVHRDIKPEN 1163
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 53.1 bits (126), Expect = 3e-07 Identities = 31/83 (37%), Positives = 47/83 (56%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E+ L L H H+ L ET + + + YC GG+L + +Q DR+ S R Sbjct: 57 EIDALKSLRHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQ-DRL-SEEETRVVFR 114 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 +++SA+A +H+ G A+RDLKPEN Sbjct: 115 QILSAVAYVHSQGYAHRDLKPEN 137
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 52.8 bits (125), Expect = 3e-07 Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 3/132 (2%) Frame = +1 Query: 40 AARVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 A R++G+G G V+LV + + + S E ++L R + P Sbjct: 304 ALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTSLDESP 363 Query: 220 SLLGRA---ETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA 390 ++G +T L Y +GG+L Q + F +FY AELV AL LH Sbjct: 364 FIVGLKFSFQTASDLYLITDYMSGGEL--FWHLQHEGRFPEQRAKFYIAELVLALEHLHK 421 Query: 391 AGIAYRDLKPEN 426 I YRDLKPEN Sbjct: 422 HDIIYRDLKPEN 433
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 52.8 bits (125), Expect = 3e-07 Identities = 44/132 (33%), Positives = 58/132 (43%), Gaps = 6/132 (4%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL--AHPH 213 VLG+G+ G V L +D YA+K+ + +++ R PH Sbjct: 341 VLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPH 400 Query: 214 -LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA 390 L L +TPD L + M Y GGDL + Q F FYAAE+ L LH Sbjct: 401 FLTQLHSTFQTPDRLYFVMEYVTGGDL--MYHIQQLGKFKEPHAAFYAAEIAIGLFFLHN 458 Query: 391 AGIAYRDLKPEN 426 GI YRDLK +N Sbjct: 459 QGIIYRDLKLDN 470
>CTRO_MOUSE (P49025) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2055 Score = 52.8 bits (125), Expect = 3e-07 Identities = 42/139 (30%), Positives = 64/139 (46%), Gaps = 6/139 (4%) Frame = +1 Query: 28 PSARAARV---LGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSV 189 PSAR V +G G V +V A YA+K+ +++ E ++ Sbjct: 92 PSARDFEVRSLVGCGHFAEVQVVREKATGDVYAMKIMKKKALLAQEQVSFFEE---ERNI 148 Query: 190 LSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVS 369 LSR P +P L + + L M Y GGD L D++ + ++FY AEL+ Sbjct: 149 LSRSTSPWIPQLQYAFQDKNNLYLVMEYQPGGDFLSLLNRYEDQL-DESMIQFYLAELIL 207 Query: 370 ALADLHAAGIAYRDLKPEN 426 A+ +H G +RD+KPEN Sbjct: 208 AVHSVHQMGYVHRDIKPEN 226
>KPCZ_RABIT (O19111) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 591 Score = 52.8 bits (125), Expect = 3e-07 Identities = 50/149 (33%), Positives = 63/149 (42%), Gaps = 7/149 (4%) Frame = +1 Query: 1 GTGVMDIDLPSARAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXX 171 G G+ D DL RV+GRG+ V LV YA+KV + Sbjct: 245 GLGLQDFDL-----IRVIGRGSYAKVLLVRLKKNGQVYAMKVVKKE------LVHDDEDI 293 Query: 172 XW---EVSVLSRLA-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAA 339 W E V + + +P L L +T L + Y GGDL + Q R Sbjct: 294 DWVQTEKHVFEQASGNPFLVGLHSCFQTTSRLFLVIEYVNGGDL--MFHMQRQRKLPEEH 351 Query: 340 VRFYAAELVSALADLHAAGIAYRDLKPEN 426 RFYAAE+ AL LH GI YRDLK +N Sbjct: 352 ARFYAAEICIALNFLHERGIIYRDLKLDN 380
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 52.8 bits (125), Expect = 3e-07 Identities = 44/132 (33%), Positives = 58/132 (43%), Gaps = 6/132 (4%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL--AHPH 213 VLG+G+ G V L +D YA+K+ + +++ R PH Sbjct: 356 VLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPH 415 Query: 214 -LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA 390 L L +TPD L + M Y GGDL + Q F FYAAE+ L LH Sbjct: 416 FLTQLHSTFQTPDRLYFVMEYVTGGDL--MYHIQQLGKFKEPHAAFYAAEIAIGLFFLHN 473 Query: 391 AGIAYRDLKPEN 426 GI YRDLK +N Sbjct: 474 QGIIYRDLKLDN 485
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 52.8 bits (125), Expect = 3e-07 Identities = 44/132 (33%), Positives = 58/132 (43%), Gaps = 6/132 (4%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL--AHPH 213 VLG+G+ G V L +D YA+K+ + +++ R PH Sbjct: 356 VLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPH 415 Query: 214 -LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA 390 L L +TPD L + M Y GGDL + Q F FYAAE+ L LH Sbjct: 416 FLTQLHSTFQTPDRLYFVMEYVTGGDL--MYHIQQLGKFKEPHAAFYAAEIAIGLFFLHN 473 Query: 391 AGIAYRDLKPEN 426 GI YRDLK +N Sbjct: 474 QGIIYRDLKLDN 485
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 52.8 bits (125), Expect = 3e-07 Identities = 44/132 (33%), Positives = 58/132 (43%), Gaps = 6/132 (4%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL--AHPH 213 VLG+G+ G V L +D YA+K+ + +++ R PH Sbjct: 356 VLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPH 415 Query: 214 -LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA 390 L L +TPD L + M Y GGDL + Q F FYAAE+ L LH Sbjct: 416 FLTQLHSTFQTPDRLYFVMEYVTGGDL--MYHIQQLGKFKEPHAAFYAAEIAIGLFFLHN 473 Query: 391 AGIAYRDLKPEN 426 GI YRDLK +N Sbjct: 474 QGIIYRDLKLDN 485
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 52.8 bits (125), Expect = 3e-07 Identities = 44/132 (33%), Positives = 58/132 (43%), Gaps = 6/132 (4%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL--AHPH 213 VLG+G+ G V L +D YA+K+ + +++ R PH Sbjct: 356 VLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPH 415 Query: 214 -LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHA 390 L L +TPD L + M Y GGDL + Q F FYAAE+ L LH Sbjct: 416 FLTQLHSTFQTPDRLYFVMEYVTGGDL--MYHIQQLGKFKEPHAAFYAAEIAIGLFFLHN 473 Query: 391 AGIAYRDLKPEN 426 GI YRDLK +N Sbjct: 474 QGIIYRDLKLDN 485
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 52.8 bits (125), Expect = 3e-07 Identities = 33/83 (39%), Positives = 42/83 (50%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E SVL ++HP L L L M Y GG+L R + FS FY+A Sbjct: 97 EKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGR--FSSTTGLFYSA 154 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 E++ A+ LH+ I YRDLKPEN Sbjct: 155 EIICAIEYLHSKEIVYRDLKPEN 177
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 52.8 bits (125), Expect = 3e-07 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 3/131 (2%) Frame = +1 Query: 43 ARVLGRGAMGTV---FLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPH 213 +R LG G+ V V + A+KV D++ ++ + R HP+ Sbjct: 65 SRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR--HPN 122 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 + LL ET + M C GG+L + + + + R Y +L+SA+ LH A Sbjct: 123 ITQLLDILETENSYYLVMELCPGGNL--MHKIYEKKRLEESEARRYIRQLISAVEHLHRA 180 Query: 394 GIAYRDLKPEN 426 G+ +RDLK EN Sbjct: 181 GVVHRDLKIEN 191
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 52.8 bits (125), Expect = 3e-07 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 3/131 (2%) Frame = +1 Query: 43 ARVLGRGAMGTV---FLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPH 213 +R LG G+ V V + A+KV D++ ++ + R HP+ Sbjct: 65 SRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR--HPN 122 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 + LL ET + M C GG+L + + + + R Y +L+SA+ LH A Sbjct: 123 ITQLLDILETENSYYLVMELCPGGNL--MHKIYEKKRLEESEARRYIRQLISAVEHLHRA 180 Query: 394 GIAYRDLKPEN 426 G+ +RDLK EN Sbjct: 181 GVVHRDLKIEN 191
>GRK7_HUMAN (Q8WTQ7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 52.4 bits (124), Expect = 4e-07 Identities = 40/130 (30%), Positives = 55/130 (42%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 RVLG+G G V V YA K D++ E +L +++ P + Sbjct: 195 RVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALL---EKEILEKVSSPFI 251 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 SL E+ L M GGDL R + V FY+A++ + LH G Sbjct: 252 VSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQIACGMLHLHELG 311 Query: 397 IAYRDLKPEN 426 I YRD+KPEN Sbjct: 312 IVYRDMKPEN 321
>CTRO_HUMAN (O14578) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2027 Score = 52.4 bits (124), Expect = 4e-07 Identities = 30/83 (36%), Positives = 44/83 (53%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E ++LSR P +P L + + L M Y GGDL L D++ ++FY A Sbjct: 145 ERNILSRSTSPWIPQLQYAFQDKNHLYLVMEYQPGGDLLSLLNRYEDQL-DENLIQFYLA 203 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 EL+ A+ +H G +RD+KPEN Sbjct: 204 ELILAVHSVHLMGYVHRDIKPEN 226
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 52.4 bits (124), Expect = 4e-07 Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV + YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>GRK7_SPETR (Q9Z2G7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 548 Score = 52.0 bits (123), Expect = 6e-07 Identities = 41/130 (31%), Positives = 54/130 (41%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAA---DAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 RVLG+G G V V YA K D++ E +L ++ P + Sbjct: 190 RVLGKGGFGEVCAVQVRNTGKMYACKKLDKKRLKKKGGEKMALL---EKEILEKVNSPFI 246 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 SL E+ L M GGDL R + + V FY A++ + LH G Sbjct: 247 VSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLAMSRVIFYTAQMTCGVLHLHGLG 306 Query: 397 IAYRDLKPEN 426 I YRDLKPEN Sbjct: 307 IVYRDLKPEN 316
>NEK4_MOUSE (Q9Z1J2) Serine/threonine-protein kinase Nek4 (EC 2.7.11.1)| (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) Length = 792 Score = 52.0 bits (123), Expect = 6e-07 Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAA---DAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 RV+GRG+ G V LV +Y +K + R+ E +LS+L HP++ Sbjct: 10 RVVGRGSYGEVTLVKHRRDGKQYVIKKLNLRN----ASSRERRAAEQEAQLLSQLKHPNI 65 Query: 217 PSLLGRAETPD-LLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 + E D LL M +C GGDL + Q ++ + V + ++ AL LH Sbjct: 66 VTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPESQVVEWFVQIAMALQYLHEK 125 Query: 394 GIAYRDLKPEN 426 I +RDLK +N Sbjct: 126 HILHRDLKTQN 136
>GRK5_RAT (Q62833) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 52.0 bits (123), Expect = 6e-07 Identities = 39/130 (30%), Positives = 50/130 (38%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R RVLG+G G V A + R E +L ++ + Sbjct: 187 RQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQFV 246 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L ET D L + GGDL + F FYAAE++ L DLH Sbjct: 247 VNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHREN 306 Query: 397 IAYRDLKPEN 426 YRDLKPEN Sbjct: 307 TVYRDLKPEN 316
>GRK5_MOUSE (Q8VEB1) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 52.0 bits (123), Expect = 6e-07 Identities = 39/130 (30%), Positives = 50/130 (38%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R RVLG+G G V A + R E +L ++ + Sbjct: 187 RQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQFV 246 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L ET D L + GGDL + F FYAAE++ L DLH Sbjct: 247 VNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHREN 306 Query: 397 IAYRDLKPEN 426 YRDLKPEN Sbjct: 307 TVYRDLKPEN 316
>GRK5_HUMAN (P34947) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 52.0 bits (123), Expect = 6e-07 Identities = 39/130 (30%), Positives = 50/130 (38%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R RVLG+G G V A + R E +L ++ + Sbjct: 187 RQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQFV 246 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L ET D L + GGDL + F FYAAE++ L DLH Sbjct: 247 VNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHREN 306 Query: 397 IAYRDLKPEN 426 YRDLKPEN Sbjct: 307 TVYRDLKPEN 316
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 52.0 bits (123), Expect = 6e-07 Identities = 37/133 (27%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHA---PGXXXXXXXXXXWEVSVLSRLAH 207 R LG GA G V LV ++A+K+ + + P E ++ L+H Sbjct: 178 RKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSH 237 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + + + PD + + + GGDL L R +++ S + Y ++ A+ LH Sbjct: 238 PCVVRMHDIVDKPDSVYMVLEFMRGGDL--LNRIISNKLLSEDISKLYFYQMCHAVKYLH 295 Query: 388 AAGIAYRDLKPEN 426 GI +RDLKP+N Sbjct: 296 DRGITHRDLKPDN 308
>KAPC_ENCCU (Q8SRK8) Probable cAMP-dependent protein kinase catalytic subunit| (EC 2.7.11.11) Length = 322 Score = 52.0 bits (123), Expect = 6e-07 Identities = 44/133 (33%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE----YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL-AHP 210 +V+G GA G V LV + +A+K+ D E+S+L R+ P Sbjct: 11 KVVGVGAFGKVHLVRLKSSPTSVFAMKMLD---FGEILRQRLADQLENEISILKRIYGCP 67 Query: 211 HLPSLLGRAETPDLLAWAMPYCAGGDLNE-LRRAQPDRVFSPAAVRFYAAELVSALADLH 387 + L + M Y GG+L L++ F RFYAAE++SAL +H Sbjct: 68 FVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGR---FDEQMARFYAAEIISALRFIH 124 Query: 388 AAGIAYRDLKPEN 426 GI YRDLKPEN Sbjct: 125 GRGILYRDLKPEN 137
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 52.0 bits (123), Expect = 6e-07 Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL-AHPH 213 ++LG+G+ G VFL + +A+K + E VLS HP Sbjct: 384 KMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMV---EKRVLSLAWEHPF 440 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + +T + L + M Y GGDL + Q F + FYAAE++ L LH+ Sbjct: 441 LTHMFCTFQTKENLFFVMEYLNGGDL--MYHIQSCHKFDLSRATFYAAEIILGLQFLHSK 498 Query: 394 GIAYRDLKPEN 426 GI YRDLK +N Sbjct: 499 GIVYRDLKLDN 509
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 52.0 bits (123), Expect = 6e-07 Identities = 29/83 (34%), Positives = 45/83 (54%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E+S++ RL+HP++ L T + +AM + GG+L + S R Y Sbjct: 70 EISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGEL--FNKISKHGRLSEDLSRRYFQ 127 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 +L+SA+ HA G+ +RDLKPEN Sbjct: 128 QLISAVGYCHARGVYHRDLKPEN 150
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 52.0 bits (123), Expect = 6e-07 Identities = 42/131 (32%), Positives = 58/131 (44%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 52.0 bits (123), Expect = 6e-07 Identities = 42/131 (32%), Positives = 58/131 (44%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 52.0 bits (123), Expect = 6e-07 Identities = 42/131 (32%), Positives = 58/131 (44%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 52.0 bits (123), Expect = 6e-07 Identities = 42/131 (32%), Positives = 58/131 (44%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV YA+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 52.0 bits (123), Expect = 6e-07 Identities = 44/130 (33%), Positives = 59/130 (45%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+G+G+ G V L D YA+KV R+ ++ LS P L Sbjct: 375 KVIGKGSFGKVLLAERRGTDELYAVKVL-RKDVIIQTDDMELPMNEKKILALSGRP-PFL 432 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 S+ +T D L + M YC GGDL + Q F + FYA E+ AL LH Sbjct: 433 VSMHSCFQTMDRLFFVMEYCKGGDL--MYHMQQYGRFKESVAIFYAVEVAIALFFLHERD 490 Query: 397 IAYRDLKPEN 426 I YRDLK +N Sbjct: 491 IIYRDLKLDN 500
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 51.6 bits (122), Expect = 8e-07 Identities = 40/133 (30%), Positives = 56/133 (42%), Gaps = 3/133 (2%) Frame = +1 Query: 37 RAARVLGRGAMGTVFL---VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 R R LG G MG V+L V+ + A+KV HA E +LS + H Sbjct: 14 RVLRPLGSGGMGEVYLGEQVSLGRKVAIKVLHHDLHAQAGMAERFKR---EARLLSAVEH 70 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P + ++ E+ D M + G L ++ P P +L LA +H Sbjct: 71 PAVVRIVDFGESGDHACLVMEFVEGESLYDVLTPGP---MPPGRALPLLQQLAEGLAAIH 127 Query: 388 AAGIAYRDLKPEN 426 GI +RDLKPEN Sbjct: 128 DKGIIHRDLKPEN 140
>WIN1_SCHPO (O74304) MAP kinase kinase kinase win1 (EC 2.7.11.25)| Length = 1436 Score = 51.6 bits (122), Expect = 8e-07 Identities = 35/127 (27%), Positives = 58/127 (45%), Gaps = 1/127 (0%) Frame = +1 Query: 49 VLGRGAMGTVF-LVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPSL 225 ++G G+ GTV+ V D + V + H P E+ VL HP++ S Sbjct: 1125 LIGSGSFGTVYRAVNLDTGDLMAVKEVALHKPRISRPMIKRIKGEMLVLELFDHPNVVSY 1184 Query: 226 LGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAY 405 G + + M C G L E R R+ ++ Y +L+ LA +H+ G+++ Sbjct: 1185 YGIEVHREKVNIFMELCQGSSLFEFLRY--GRIEDELVIQVYVLQLLEGLAYIHSCGVSH 1242 Query: 406 RDLKPEN 426 +D+KPEN Sbjct: 1243 QDVKPEN 1249
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 51.6 bits (122), Expect = 8e-07 Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL-AHPH 213 ++LG+G+ G VFL + +A+K + E VLS HP Sbjct: 384 KMLGKGSFGKVFLAEFKRTNQFFAIKALKKDVVLMDDDVECTMV---EKRVLSLAWEHPF 440 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + +T + L + M Y GGDL + Q F + FYAAE++ L LH+ Sbjct: 441 LTHMFCTFQTKENLFFVMEYLNGGDL--MYHIQSCHKFDLSRATFYAAEVILGLQFLHSK 498 Query: 394 GIAYRDLKPEN 426 GI YRDLK +N Sbjct: 499 GIVYRDLKLDN 509
>RK_BOVIN (P28327) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 561 Score = 51.6 bits (122), Expect = 8e-07 Identities = 41/129 (31%), Positives = 52/129 (40%), Gaps = 2/129 (1%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPSL 225 RVLGRG G VF A L + + E +L+++ + SL Sbjct: 191 RVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSL 250 Query: 226 LGRAETPDLLAWAMPYCAGGDLN-ELRRAQPDRV-FSPAAVRFYAAELVSALADLHAAGI 399 ET L M GGD+ + D F FY A++VS L LH I Sbjct: 251 AYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNI 310 Query: 400 AYRDLKPEN 426 YRDLKPEN Sbjct: 311 IYRDLKPEN 319
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 51.6 bits (122), Expect = 8e-07 Identities = 40/128 (31%), Positives = 57/128 (44%), Gaps = 3/128 (2%) Frame = +1 Query: 52 LGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPS 222 LGRGA V+ YALKV + E+ VL RL+HP++ Sbjct: 48 LGRGATSIVYRCKQKGTQKPYALKVLKK--------TVDKKIVRTEIGVLLRLSHPNIIK 99 Query: 223 LLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIA 402 L ETP ++ + GG+L + R +S +++ A+A LH GI Sbjct: 100 LKEIFETPTEISLVLELVTGGELFD--RIVEKGYYSERDAADAVKQILEAVAYLHENGIV 157 Query: 403 YRDLKPEN 426 +RDLKPEN Sbjct: 158 HRDLKPEN 165
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 51.6 bits (122), Expect = 8e-07 Identities = 40/128 (31%), Positives = 57/128 (44%), Gaps = 3/128 (2%) Frame = +1 Query: 52 LGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPS 222 LGRGA V+ YALKV + E+ VL RL+HP++ Sbjct: 52 LGRGATSIVYRCKQKGTQKPYALKVLKK--------TVDKKIVRTEIGVLLRLSHPNIIK 103 Query: 223 LLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIA 402 L ETP ++ + GG+L + R +S +++ A+A LH GI Sbjct: 104 LKEIFETPTEISLVLELVTGGELFD--RIVEKGYYSERDAADAVKQILEAVAYLHENGIV 161 Query: 403 YRDLKPEN 426 +RDLKPEN Sbjct: 162 HRDLKPEN 169
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 51.6 bits (122), Expect = 8e-07 Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVF---LVAADAEYALKVFDR-RSHAPGXXXXXXXXXXWEVSVLSRLAHPH 213 R++GRG G V+ YA+K D+ R +V + + P Sbjct: 195 RIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGEMLALNERNMLQAVSTGIDCPF 254 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 + + TPD L + + GGDL+ +FS ++FYAAE++ L +H Sbjct: 255 IVCMTYAFHTPDKLCFILDLMNGGDLHY--HLSQHGIFSEDEMKFYAAEVILGLEHMHKR 312 Query: 394 GIAYRDLKPEN 426 I YRDLKP N Sbjct: 313 CIVYRDLKPAN 323
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 51.2 bits (121), Expect = 1e-06 Identities = 47/134 (35%), Positives = 61/134 (45%), Gaps = 7/134 (5%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG GA G VFLV A YA+KV + + E VL + Sbjct: 43 KVLGTGAYGKVFLVRKVSGHDAGKLYAMKVLKKATIVQKAKTTEHTRT--ERQVLEHIRQ 100 Query: 208 -PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADL 384 P L +L +T L + Y GG+L +Q +R FS V+ Y E+V AL L Sbjct: 101 SPFLVTLHYAFQTDTKLHLILDYINGGEL-FTHLSQRER-FSENEVQIYIGEIVLALEHL 158 Query: 385 HAAGIAYRDLKPEN 426 H GI YRD+K EN Sbjct: 159 HKLGIIYRDIKLEN 172 Score = 41.2 bits (95), Expect = 0.001 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 1/110 (0%) Frame = +1 Query: 100 EYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL-AHPHLPSLLGRAETPDLLAWAMPYC 276 EYA+K+ +R A E++ L HP++ L M Sbjct: 441 EYAVKIISKRMEA---------NTQREITALKLCEGHPNVVKLHEVYHDQLHTFLVMELL 491 Query: 277 AGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L L R Q + FS LVSA++ +H G+ +RDLKPEN Sbjct: 492 KGGEL--LERIQKKQHFSETEASHIMRRLVSAVSHMHDVGVVHRDLKPEN 539
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 51.2 bits (121), Expect = 1e-06 Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV YA+K+ D++ E +L + P L Sbjct: 85 KTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLN---EKRILQAIDFPFL 141 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 ++ + L + + +GG++ + LRR FS RFYAA++V A LH+ Sbjct: 142 VNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGR---FSEPHSRFYAAQIVLAFEYLHSL 198 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 199 DLIYRDLKPEN 209
>GRK4_RAT (P70507) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 575 Score = 51.2 bits (121), Expect = 1e-06 Identities = 44/133 (33%), Positives = 53/133 (39%), Gaps = 3/133 (2%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 R RVLG+G G V A YA K +++ E +L +L Sbjct: 187 RQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALN---EKRILEKLHS 243 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 + SL ET D L + GGDL + F FYAAEL L DL Sbjct: 244 RFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGNPGFEEQRAVFYAAELCCGLEDLQ 303 Query: 388 AAGIAYRDLKPEN 426 I YRDLKPEN Sbjct: 304 RERIVYRDLKPEN 316
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 51.2 bits (121), Expect = 1e-06 Identities = 41/131 (31%), Positives = 59/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V +V YA+K+ D++ E +L + P L Sbjct: 49 KTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLN---EKRILQAIQFPFL 105 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 SL + L + Y GG++ + LR+ FS RFYAA++V A LH Sbjct: 106 VSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGR---FSEPHSRFYAAQIVLAFEYLHYL 162 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 163 DLIYRDLKPEN 173
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 50.8 bits (120), Expect = 1e-06 Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE--YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL------ 201 R +G GA +V L D YA+K F + HA W + S + Sbjct: 14 REIGTGAFASVRLCYDDNAKIYAVK-FVNKKHA----TSCMNAGVWARRMASEIQLHKLC 68 Query: 202 -AHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALA 378 H ++ AE P + + GGDL + + +PD +FY A+L+ ++ Sbjct: 69 NGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFD--KIEPDVGIDEDVAQFYFAQLMEGIS 126 Query: 379 DLHAAGIAYRDLKPEN 426 +H+ G+A+RDLKPEN Sbjct: 127 FMHSKGVAHRDLKPEN 142
>ATG1_YARLI (Q6C7U0) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 710 Score = 50.8 bits (120), Expect = 1e-06 Identities = 43/147 (29%), Positives = 62/147 (42%), Gaps = 22/147 (14%) Frame = +1 Query: 52 LGRGAMGTVFL---VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPS 222 LGRG+ TV+ VA+ + A+K R E+S+L ++ HPH+ Sbjct: 13 LGRGSFATVYKGEHVASGSPVAIKSVLRAK----LNRKLLENLGSEISILKQMKHPHVVE 68 Query: 223 LLGRAETPDLLAWAMPYCAGGDLN-------ELRRAQP------------DRVFSPAAVR 345 LL ETP M YC+ GDL+ EL P R VR Sbjct: 69 LLDFQETPTHFHLVMEYCSLGDLSFFLKKKKELSETLPLVASLLRRYPSNTRGLHEELVR 128 Query: 346 FYAAELVSALADLHAAGIAYRDLKPEN 426 + +L +AL L + +RD+KP+N Sbjct: 129 HFVHQLSAALEFLRQKNLVHRDIKPQN 155
>PKAA_STRCO (P54739) Serine/threonine protein kinase pkaA (EC 2.7.11.1)| Length = 543 Score = 50.8 bits (120), Expect = 1e-06 Identities = 47/140 (33%), Positives = 60/140 (42%), Gaps = 15/140 (10%) Frame = +1 Query: 52 LGRGAMGTVFLV----AADAE----------YALKVFDRRSHAPGXXXXXXXXXXWEVSV 189 LGRGA GTV+ A AE A+KV + E SV Sbjct: 14 LGRGATGTVWRARQRETAGAEAAVAGQPGETVAIKVLKEELASDADIVMRFLR---ERSV 70 Query: 190 LSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNE-LRRAQPDRVFSPAAVRFYAAELV 366 L RL HP++ + +LLA M G DL+ LR P +P A A++ Sbjct: 71 LLRLTHPNIVRVRDLVVEGELLALVMDLIDGPDLHRYLRENGP---LTPVAAALLTAQIA 127 Query: 367 SALADLHAAGIAYRDLKPEN 426 ALA HA G+ +RDLKP N Sbjct: 128 DALAASHADGVVHRDLKPAN 147
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 50.4 bits (119), Expect = 2e-06 Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV +A+K+ D++ E +L + P L Sbjct: 46 KTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 102 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 103 VKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 159 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 160 DLIYRDLKPEN 170
>CHK1_CAEEL (Q9N3Z3) Serine/threonine-protein kinase chk-1 (EC 2.7.11.1)| Length = 503 Score = 50.4 bits (119), Expect = 2e-06 Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 4/134 (2%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVA----ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLA 204 R + LG GA G V L+ + A+K + + + + V S + Sbjct: 25 RVVQTLGEGAFGEVLLIVNTKNPEVAAAMKKINIANKSKDFIDNIRKEYLLQKRV-SAVG 83 Query: 205 HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADL 384 H ++ ++G P + Y GG+L + + +PD SP +FY +L+ L + Sbjct: 84 HDNVIRMIGMRNDPQFYYLFLEYADGGELFD--KIEPDCGMSPVFAQFYFKQLICGLKFI 141 Query: 385 HAAGIAYRDLKPEN 426 H + +RD+KPEN Sbjct: 142 HDNDVVHRDIKPEN 155
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 50.4 bits (119), Expect = 2e-06 Identities = 28/83 (33%), Positives = 47/83 (56%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E++VL R++HP++ +L E+P L AM GG+L + R ++ Sbjct: 61 EIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFD--RIMERGSYTEKDASHLVG 118 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 +++ A++ LH+ GI +RDLKPEN Sbjct: 119 QVLGAVSYLHSLGIVHRDLKPEN 141
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 50.4 bits (119), Expect = 2e-06 Identities = 28/83 (33%), Positives = 47/83 (56%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E++VL R++HP++ +L E+P L AM GG+L + R ++ Sbjct: 61 EIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFD--RIMERGSYTEKDASHLVG 118 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 +++ A++ LH+ GI +RDLKPEN Sbjct: 119 QVLGAVSYLHSLGIVHRDLKPEN 141
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 50.4 bits (119), Expect = 2e-06 Identities = 28/83 (33%), Positives = 47/83 (56%) Frame = +1 Query: 178 EVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAA 357 E++VL R++HP++ +L E+P L AM GG+L + R ++ Sbjct: 61 EIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFD--RIMERGSYTEKDASHLVG 118 Query: 358 ELVSALADLHAAGIAYRDLKPEN 426 +++ A++ LH+ GI +RDLKPEN Sbjct: 119 QVLGAVSYLHSLGIVHRDLKPEN 141
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 50.4 bits (119), Expect = 2e-06 Identities = 37/127 (29%), Positives = 59/127 (46%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPSL 225 RVLG GA G L + +L V+ A E+ +LS L H ++ + Sbjct: 38 RVLGHGAYGEATLYRRTEDDSLVVWKEVGLARLSEKERRDALN-EIVILSLLQHDNIIAY 96 Query: 226 LGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAY 405 + L + YC GG+L + Q ++F V +Y ++VSA++ +H AGI + Sbjct: 97 YNHFLDSNTLLIELEYCNGGNLFDKIVHQKAQLFQEETVLWYLFQIVSAVSCIHKAGILH 156 Query: 406 RDLKPEN 426 RD+K N Sbjct: 157 RDIKTLN 163
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 50.4 bits (119), Expect = 2e-06 Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV +A+K+ D++ E +L + P L Sbjct: 47 KTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLN---EKRILQAVNFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS RFYAA++V LH+ Sbjct: 104 VKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHSL 160 Query: 394 GIAYRDLKPEN 426 + YRDLKPEN Sbjct: 161 DLIYRDLKPEN 171
>ROCK2_BOVIN (Q28021) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 50.4 bits (119), Expect = 2e-06 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH-PH 213 +V+GRGA G V LV A+ YA+K+ + WE + A+ P Sbjct: 96 KVIGRGAFGEVQLVRHKASQKVYAMKLLSKFE----MIKRSDSAFFWEERDIMAFANSPW 151 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQ--PDRVFSPAAVRFYAAELVSALADLH 387 + L + L M Y GGDL L P++ +FY AE+V AL +H Sbjct: 152 VVQLFCAFQDDKYLYMVMEYMPGGDLVNLMSNYDVPEKW-----AKFYTAEVVLALDAIH 206 Query: 388 AAGIAYRDLKPEN 426 + G+ +RD+KP+N Sbjct: 207 SMGLIHRDVKPDN 219
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 50.4 bits (119), Expect = 2e-06 Identities = 46/134 (34%), Positives = 61/134 (45%), Gaps = 7/134 (5%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG GA G VFLV A YA+KV + + E VL + Sbjct: 52 KVLGTGAYGKVFLVRKISGHDAGKLYAMKVLKKATIVQKAKTTEHTRT--ERQVLEHIRQ 109 Query: 208 -PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADL 384 P L +L +T L + Y GG+L +Q +R F+ V+ Y E+V AL L Sbjct: 110 SPFLVTLHYAFQTETKLHLILDYINGGEL-FTHLSQRER-FTEHEVQIYVGEIVLALEHL 167 Query: 385 HAAGIAYRDLKPEN 426 H GI YRD+K EN Sbjct: 168 HKLGIIYRDIKLEN 181 Score = 39.3 bits (90), Expect = 0.004 Identities = 20/49 (40%), Positives = 30/49 (61%) Frame = +1 Query: 280 GGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L E R + + FS + +LVSA++ +H G+ +RDLKPEN Sbjct: 567 GGELFE--RIKRKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPEN 613
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 50.1 bits (118), Expect = 2e-06 Identities = 36/109 (33%), Positives = 52/109 (47%) Frame = +1 Query: 100 EYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCA 279 EYALK+ ++S G EVS+L R+ HP++ L+ + P L M Sbjct: 431 EYALKII-KKSKCRGKEHMIQN----EVSILRRVKHPNIVLLIEEMDVPTELYLVMELVK 485 Query: 280 GGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GGDL + + A+ Y L SA+ LH+ I +RD+KPEN Sbjct: 486 GGDLFDAITSTSKYTERDASGMLY--NLASAIKYLHSLNIVHRDIKPEN 532
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 50.1 bits (118), Expect = 2e-06 Identities = 36/109 (33%), Positives = 52/109 (47%) Frame = +1 Query: 100 EYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCA 279 EYALK+ ++S G EVS+L R+ HP++ L+ + P L M Sbjct: 108 EYALKII-KKSKCRGKEHMIQN----EVSILRRVKHPNIVLLIEEMDVPTELYLVMELVK 162 Query: 280 GGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GGDL + + A+ Y L SA+ LH+ I +RD+KPEN Sbjct: 163 GGDLFDAITSTSKYTERDASGMLY--NLASAIKYLHSLNIVHRDIKPEN 209
>PKN3_HUMAN (Q6P5Z2) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 889 Score = 50.1 bits (118), Expect = 2e-06 Identities = 43/137 (31%), Positives = 55/137 (40%), Gaps = 3/137 (2%) Frame = +1 Query: 25 LPSARAARVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLS 195 L R VLGRG G V LV YA+K ++ + + Sbjct: 556 LQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVG 615 Query: 196 RLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSAL 375 HP L SLL +T + + GGDL + + D VF RFY A +V L Sbjct: 616 CTGHPFLLSLLACFQTSSHACFVTEFVPGGDL--MMQIHED-VFPEPQARFYVACVVLGL 672 Query: 376 ADLHAAGIAYRDLKPEN 426 LH I YRDLK +N Sbjct: 673 QFLHEKKIIYRDLKLDN 689
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 50.1 bits (118), Expect = 2e-06 Identities = 40/130 (30%), Positives = 57/130 (43%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 R LG G+ G V LV YA+K+ +++ E +L + P L Sbjct: 47 RTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILN---EKRILQAIDFPFL 103 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L + L M Y GG++ R Q FS FYAA++V A+ LH+ Sbjct: 104 VKLQFSFKDNSYLYLVMEYVPGGEM--FSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD 161 Query: 397 IAYRDLKPEN 426 + +RDLKPEN Sbjct: 162 LIHRDLKPEN 171
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 50.1 bits (118), Expect = 2e-06 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH-PH 213 +V+GRGA G V LV A+ YA+K+ + WE + A+ P Sbjct: 87 KVIGRGAFGEVQLVRHKASQKVYAMKLLSKFE----MIKRSDSAFFWEERDIMAFANSPW 142 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQ--PDRVFSPAAVRFYAAELVSALADLH 387 + L + L M Y GGDL L P++ +FY AE+V AL +H Sbjct: 143 VVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKW-----AKFYTAEVVLALDAIH 197 Query: 388 AAGIAYRDLKPEN 426 + G+ +RD+KP+N Sbjct: 198 SMGLIHRDVKPDN 210
>ROCK2_MOUSE (P70336) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 50.1 bits (118), Expect = 2e-06 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH-PH 213 +V+GRGA G V LV A+ YA+K+ + WE + A+ P Sbjct: 96 KVIGRGAFGEVQLVRHKASQKVYAMKLLSKFE----MIKRSDSAFFWEERDIMAFANSPW 151 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQ--PDRVFSPAAVRFYAAELVSALADLH 387 + L + L M Y GGDL L P++ +FY AE+V AL +H Sbjct: 152 VVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKW-----AKFYTAEVVLALDAIH 206 Query: 388 AAGIAYRDLKPEN 426 + G+ +RD+KP+N Sbjct: 207 SMGLIHRDVKPDN 219
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 50.1 bits (118), Expect = 2e-06 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH-PH 213 +V+GRGA G V LV A+ YA+K+ + WE + A+ P Sbjct: 96 KVIGRGAFGEVQLVRHKASQKVYAMKLLSKFE----MIKRSDSAFFWEERDIMAFANSPW 151 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQ--PDRVFSPAAVRFYAAELVSALADLH 387 + L + L M Y GGDL L P++ +FY AE+V AL +H Sbjct: 152 VVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKW-----AKFYTAEVVLALDAIH 206 Query: 388 AAGIAYRDLKPEN 426 + G+ +RD+KP+N Sbjct: 207 SMGLIHRDVKPDN 219
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 49.7 bits (117), Expect = 3e-06 Identities = 44/133 (33%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG GA G VFLV YA+KV + + +V +R + Sbjct: 53 KVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHTRQS- 111 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 P L +L +T L + Y GG+L +Q +R F+ V+ Y E+V AL LH Sbjct: 112 PFLVTLHYAFQTETKLHLILDYINGGEL-FTHLSQRER-FTEHEVQIYVGEIVLALEHLH 169 Query: 388 AAGIAYRDLKPEN 426 GI YRD+K EN Sbjct: 170 KLGIIYRDIKLEN 182 Score = 39.7 bits (91), Expect = 0.003 Identities = 20/49 (40%), Positives = 30/49 (61%) Frame = +1 Query: 280 GGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L E R + + FS + +LVSA++ +H G+ +RDLKPEN Sbjct: 503 GGELFE--RIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPEN 549
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 49.7 bits (117), Expect = 3e-06 Identities = 36/109 (33%), Positives = 52/109 (47%) Frame = +1 Query: 100 EYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPSLLGRAETPDLLAWAMPYCA 279 EYALK+ ++S G EVS+L R+ HP++ L+ + P L M Sbjct: 415 EYALKII-KKSKCRGKEHMIQN----EVSILRRVKHPNIVLLIEEMDVPTELYLVMELVK 469 Query: 280 GGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GGDL + + A+ Y L SA+ LH+ I +RD+KPEN Sbjct: 470 GGDLFDAITSTNKYTERDASGMLY--NLASAIKYLHSLNIVHRDIKPEN 516
>RAD53_YEAST (P22216) Serine/threonine-protein kinase RAD53 (EC 2.7.11.1)| (Serine-protein kinase 1) Length = 821 Score = 49.7 bits (117), Expect = 3e-06 Identities = 36/129 (27%), Positives = 60/129 (46%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 V+G+GA TV +A+K+ +R E+ VL +L HP + Sbjct: 203 VVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTR-----ELEVLQKLNHPRIV 257 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L G E + M + +GGDL + A A R + ++++A+ +H+ GI Sbjct: 258 RLKGFYEDTESYYMVMEFVSGGDLMDFVAAHG--AVGEDAGREISRQILTAIKYIHSMGI 315 Query: 400 AYRDLKPEN 426 ++RDLKP+N Sbjct: 316 SHRDLKPDN 324
>UNC51_CAEEL (Q23023) Serine/threonine-protein kinase unc-51 (EC 2.7.11.1)| (Uncoordinated protein 51) Length = 856 Score = 49.7 bits (117), Expect = 3e-06 Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 4/130 (3%) Frame = +1 Query: 49 VLGRGAMGTVF----LVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +LG GA V+ + D A+K +++ + + LS L H +L Sbjct: 14 LLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKNLLTKEIKI--LKELSSLKHENL 71 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 LL ETP + M +C GGDL + Q + ++ + ++ AL ++ G Sbjct: 72 VGLLKCTETPTHVYLVMEFCNGGDLADY--LQQKTTLNEDTIQHFVVQIAHALEAINKKG 129 Query: 397 IAYRDLKPEN 426 I +RDLKP+N Sbjct: 130 IVHRDLKPQN 139
>NEK4_HUMAN (P51957) Serine/threonine-protein kinase Nek4 (EC 2.7.11.1)| (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2) Length = 841 Score = 49.7 bits (117), Expect = 3e-06 Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAA---DAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 RV+G+G+ G V LV +Y +K + R+ E +LS+L HP++ Sbjct: 10 RVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRN----ASSRERRAAEQEAQLLSQLKHPNI 65 Query: 217 PSLLGRAETPD-LLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 + E D LL M +C GGDL + Q ++ V + ++ AL LH Sbjct: 66 VTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEK 125 Query: 394 GIAYRDLKPEN 426 I +RDLK +N Sbjct: 126 HILHRDLKTQN 136
>PKN3_MOUSE (Q8K045) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 878 Score = 49.7 bits (117), Expect = 3e-06 Identities = 43/137 (31%), Positives = 55/137 (40%), Gaps = 3/137 (2%) Frame = +1 Query: 25 LPSARAARVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLS 195 L R VLGRG G V LV YA+K ++ + + Sbjct: 545 LQDFRCLAVLGRGHFGKVLLVQYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRILETVG 604 Query: 196 RLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSAL 375 R HP L SLL +T + + GGDL + + D VF FY A +V L Sbjct: 605 RTGHPFLLSLLACLQTSSHACFVTEFLPGGDL--MAQIHED-VFPEPQACFYLACVVLGL 661 Query: 376 ADLHAAGIAYRDLKPEN 426 LH I YRDLK +N Sbjct: 662 QFLHEKRIIYRDLKLDN 678
>COT1_NEUCR (P38679) Serine/threonine-protein kinase cot-1 (EC 2.7.11.1)| (Colonial temperature-sensitive 1) Length = 598 Score = 49.7 bits (117), Expect = 3e-06 Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +++G+GA G V LV A+ YA+K + E +L+ P + Sbjct: 218 KIIGKGAFGEVKLVQKKADGKVYAMKSLIKTEMFKKDQLAHVRA---ERDILAESDSPWV 274 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L + + L M + GGDL + +FS RFY AE+V A+ +H G Sbjct: 275 VKLYTTFQDANFLYMLMEFLPGGDLMTMLIKY--EIFSEDITRFYIAEIVLAIDAVHKLG 332 Query: 397 IAYRDLKPEN 426 +RD+KP+N Sbjct: 333 FIHRDIKPDN 342
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 49.3 bits (116), Expect = 4e-06 Identities = 42/130 (32%), Positives = 61/130 (46%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +VLG+G+ G V L ++ YA+K+ + +++ + P L Sbjct: 354 KVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEK--PPFL 411 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L +T D L + M Y GGDL + Q + P AV FYAAE+ + L LH G Sbjct: 412 VQLHSCFQTMDRLFFVMEYVNGGDLM-FQIQQFGKFKEPVAV-FYAAEIAAGLFFLHTKG 469 Query: 397 IAYRDLKPEN 426 I YRDLK +N Sbjct: 470 ILYRDLKLDN 479
>MRCKG_MOUSE (Q80UW5) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 49.3 bits (116), Expect = 4e-06 Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+GRGA G V +V +A+K+ + E VL + + Sbjct: 75 KVIGRGAFGEVAVVRQRGSGQIFAMKMLHKWEMLKRAETACFRE---ERDVLVKGDSRWV 131 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L + + L M Y AGGDL L DR+ P +FY AE+V A+ LH G Sbjct: 132 TALHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRL-PPELAQFYLAEMVLAIHSLHQLG 190 Query: 397 IAYRDLKPEN 426 +RD+KP+N Sbjct: 191 YVHRDVKPDN 200
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 49.3 bits (116), Expect = 4e-06 Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG GA G V L + A+K+ D + A E+ + L H ++ Sbjct: 13 QTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAADCPENIKK-----EICINKMLNHENV 67 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPD-RVFSPAAVRFYAAELVSALADLHAA 393 G + YC+GG+L + R +PD + P A RF+ +L++ + LH+ Sbjct: 68 VKFYGHRREGATQYLFLEYCSGGELFD--RIEPDIGMPEPEAQRFFQ-QLIAGVVYLHSM 124 Query: 394 GIAYRDLKPEN 426 GI +RDLKPEN Sbjct: 125 GITHRDLKPEN 135
>KGP1A_RABIT (O77676) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 49.3 bits (116), Expect = 4e-06 Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 4/129 (3%) Frame = +1 Query: 52 LGRGAMGTVFLVAADAE----YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 LG G G V LV +E +A+K+ +R E ++ + Sbjct: 365 LGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRS---EKQIMQGAHSDFIV 421 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L + L M C GG+L + R + F + RFY A +V A A LH+ GI Sbjct: 422 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGS--FEDSTTRFYTACVVEAFAYLHSKGI 479 Query: 400 AYRDLKPEN 426 YRDLKPEN Sbjct: 480 IYRDLKPEN 488
>KGP1A_HUMAN (Q13976) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 49.3 bits (116), Expect = 4e-06 Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 4/129 (3%) Frame = +1 Query: 52 LGRGAMGTVFLVAADAE----YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 LG G G V LV +E +A+K+ +R E ++ + Sbjct: 365 LGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRS---EKQIMQGAHSDFIV 421 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L + L M C GG+L + R + F + RFY A +V A A LH+ GI Sbjct: 422 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGS--FEDSTTRFYTACVVEAFAYLHSKGI 479 Query: 400 AYRDLKPEN 426 YRDLKPEN Sbjct: 480 IYRDLKPEN 488
>KGP1A_BOVIN (P00516) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 49.3 bits (116), Expect = 4e-06 Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 4/129 (3%) Frame = +1 Query: 52 LGRGAMGTVFLVAADAE----YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 LG G G V LV +E +A+K+ +R E ++ + Sbjct: 365 LGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRS---EKQIMQGAHSDFIV 421 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L + L M C GG+L + R + F + RFY A +V A A LH+ GI Sbjct: 422 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGS--FEDSTTRFYTACVVEAFAYLHSKGI 479 Query: 400 AYRDLKPEN 426 YRDLKPEN Sbjct: 480 IYRDLKPEN 488
>KGP1B_MOUSE (Q9Z0Z0) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 49.3 bits (116), Expect = 4e-06 Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 4/129 (3%) Frame = +1 Query: 52 LGRGAMGTVFLVAADAE----YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 LG G G V LV +E +A+K+ +R E ++ + Sbjct: 381 LGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRS---EKQIMQGAHSDFIV 437 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L + L M C GG+L + R + F + RFY A +V A A LH+ GI Sbjct: 438 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGS--FEDSTTRFYTACVVEAFAYLHSKGI 495 Query: 400 AYRDLKPEN 426 YRDLKPEN Sbjct: 496 IYRDLKPEN 504
>KGP1B_HUMAN (P14619) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 49.3 bits (116), Expect = 4e-06 Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 4/129 (3%) Frame = +1 Query: 52 LGRGAMGTVFLVAADAE----YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 LG G G V LV +E +A+K+ +R E ++ + Sbjct: 381 LGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRS---EKQIMQGAHSDFIV 437 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L + L M C GG+L + R + F + RFY A +V A A LH+ GI Sbjct: 438 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGS--FEDSTTRFYTACVVEAFAYLHSKGI 495 Query: 400 AYRDLKPEN 426 YRDLKPEN Sbjct: 496 IYRDLKPEN 504
>KGP1B_BOVIN (P21136) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 49.3 bits (116), Expect = 4e-06 Identities = 40/129 (31%), Positives = 55/129 (42%), Gaps = 4/129 (3%) Frame = +1 Query: 52 LGRGAMGTVFLVAADAE----YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 LG G G V LV +E +A+K+ +R E ++ + Sbjct: 381 LGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRS---EKQIMQGAHSDFIV 437 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L + L M C GG+L + R + F + RFY A +V A A LH+ GI Sbjct: 438 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGS--FEDSTTRFYTACVVEAFAYLHSKGI 495 Query: 400 AYRDLKPEN 426 YRDLKPEN Sbjct: 496 IYRDLKPEN 504
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 48.9 bits (115), Expect = 5e-06 Identities = 45/134 (33%), Positives = 60/134 (44%), Gaps = 7/134 (5%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA------ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 +VLG GA G VFLV YA+KV + + E VL + Sbjct: 53 KVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRT--ERQVLEHIRQ 110 Query: 208 -PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADL 384 P L +L +T L + Y GG+L +Q +R F+ V+ Y E+V AL L Sbjct: 111 SPFLVTLHYAFQTETKLHLILDYINGGEL-FTHLSQRER-FTEHEVQIYVGEIVLALEHL 168 Query: 385 HAAGIAYRDLKPEN 426 H GI YRD+K EN Sbjct: 169 HKLGIIYRDIKLEN 182 Score = 39.7 bits (91), Expect = 0.003 Identities = 20/49 (40%), Positives = 30/49 (61%) Frame = +1 Query: 280 GGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIAYRDLKPEN 426 GG+L E R + + FS + +LVSA++ +H G+ +RDLKPEN Sbjct: 503 GGELFE--RIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPEN 549
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 48.9 bits (115), Expect = 5e-06 Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLG+G+ G V L + YA+K+ + +++L + P L Sbjct: 343 VLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDK--PPFLT 400 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L +T D L + M Y GGDL Q + P AV FYAAE+ L LH GI Sbjct: 401 QLHSCFQTVDRLYFVMEYVNGGDLM-YHIQQVGKFKEPQAV-FYAAEISIGLFFLHKRGI 458 Query: 400 AYRDLKPEN 426 YRDLK +N Sbjct: 459 IYRDLKLDN 467
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 48.9 bits (115), Expect = 5e-06 Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLG+G+ G V L + YA+K+ + +++L + P L Sbjct: 343 VLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDK--PPFLT 400 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L +T D L + M Y GGDL Q + P AV FYAAE+ L LH GI Sbjct: 401 QLHSCFQTVDRLYFVMEYVNGGDLM-YHIQQVGKFKEPQAV-FYAAEISIGLFFLHKRGI 458 Query: 400 AYRDLKPEN 426 YRDLK +N Sbjct: 459 IYRDLKLDN 467
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 48.9 bits (115), Expect = 5e-06 Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLG+G+ G V L + YA+K+ + +++L + P L Sbjct: 343 VLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDK--PPFLT 400 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L +T D L + M Y GGDL Q + P AV FYAAE+ L LH GI Sbjct: 401 QLHSCFQTVDRLYFVMEYVNGGDLM-YHIQQVGKFKEPQAV-FYAAEISIGLFFLHKRGI 458 Query: 400 AYRDLKPEN 426 YRDLK +N Sbjct: 459 IYRDLKLDN 467
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 48.9 bits (115), Expect = 5e-06 Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 4/131 (3%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG G+ G V LV YA+K+ D++ E +L + P L Sbjct: 46 KTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVV---RLKQVEHTLNEKRILQAINFPFL 102 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDL-NELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 L + L M Y GG++ + LRR FS FYAA++V A LH+ Sbjct: 103 VKLQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGR---FSEPQACFYAAQVVLAFQYLHSL 159 Query: 394 GIAYRDLKPEN 426 + +RDLKPEN Sbjct: 160 DLIHRDLKPEN 170
>GRK4_HUMAN (P32298) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) (ITI1) Length = 578 Score = 48.9 bits (115), Expect = 5e-06 Identities = 43/133 (32%), Positives = 52/133 (39%), Gaps = 3/133 (2%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAE---YALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAH 207 R RVLG+G G V A YA K ++ E +L ++ Sbjct: 188 RHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALN---EKRILEKVQS 244 Query: 208 PHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 + SL ET D L + GGDL + F FYAAEL L DL Sbjct: 245 RFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQ 304 Query: 388 AAGIAYRDLKPEN 426 I YRDLKPEN Sbjct: 305 RERIVYRDLKPEN 317
>CHK1_CAEBR (Q61RA2) Serine/threonine-protein kinase chk-1 (EC 2.7.11.1)| Length = 493 Score = 48.9 bits (115), Expect = 5e-06 Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 1/131 (0%) Frame = +1 Query: 37 RAARVLGRGAMGTVFLVAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSV-LSRLAHPH 213 R R LG GA G V L+ + + V ++ + + LS++ H + Sbjct: 27 RVIRTLGEGAFGEVLLIVNNKNPDMAVAMKKMQITTQANTNNIRKEFLIQQKLSKVGHDN 86 Query: 214 LPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAA 393 +G + Y GG+L + + +PD A +FY +L+ L +H Sbjct: 87 FIRAIGMRTENGFHFLFLEYADGGELFD--KIEPDHGMPTAIAQFYFRQLIEGLKYIHDC 144 Query: 394 GIAYRDLKPEN 426 I +RD+KPEN Sbjct: 145 DIVHRDIKPEN 155
>DBF20_YEAST (P32328) Serine/threonine-protein kinase DBF20 (EC 2.7.11.1)| Length = 564 Score = 48.9 bits (115), Expect = 5e-06 Identities = 38/128 (29%), Positives = 56/128 (43%), Gaps = 3/128 (2%) Frame = +1 Query: 52 LGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLPS 222 +G+G G V+L +D ALK+ +++ E +L+ L Sbjct: 175 VGQGGYGQVYLAKKKDSDEICALKILNKKLL---FKLNETNHVLTERDILTTTRSDWLVK 231 Query: 223 LLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGIA 402 LL + P+ L AM + GGD L R+ RFY +E+ A+ LH G Sbjct: 232 LLYAFQDPESLYLAMEFVPGGDFRTL--LINTRILKSGHARFYISEMFCAVNALHELGYT 289 Query: 403 YRDLKPEN 426 +RDLKPEN Sbjct: 290 HRDLKPEN 297
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 48.5 bits (114), Expect = 6e-06 Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 7/133 (5%) Frame = +1 Query: 49 VLGRGAMGTVFLVAADA---EYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 +LG G+ TV ++ EYA+KV D+R + +LS+ HP Sbjct: 104 ILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILSK--HPGFI 161 Query: 220 SLLGRAETPDLLAWAMPYCAGGDL----NELRRAQPDRVFSPAAVRFYAAELVSALADLH 387 L + L + + G+L N+L R F+ ++YAA +V ++ +H Sbjct: 162 KLFYTFQDAHNLYFVLSLARNGELLDYINKLGR------FNEICAQYYAALIVDSIDYMH 215 Query: 388 AAGIAYRDLKPEN 426 G+ +RDLKPEN Sbjct: 216 GRGVIHRDLKPEN 228
>MRCKG_HUMAN (Q6DT37) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 48.5 bits (114), Expect = 6e-06 Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 +V+GRGA G V +V +A+K+ + E VL + + Sbjct: 75 KVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFRE---ERDVLVKGDSRWV 131 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 +L + + L M Y AGGDL L DR+ P +FY AE+V A+ LH G Sbjct: 132 TTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRL-PPELAQFYLAEMVLAIHSLHQLG 190 Query: 397 IAYRDLKPEN 426 +RD+KP+N Sbjct: 191 YVHRDVKPDN 200
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 48.5 bits (114), Expect = 6e-06 Identities = 41/141 (29%), Positives = 57/141 (40%), Gaps = 4/141 (2%) Frame = +1 Query: 16 DIDLPSARAARVLGRGAMGTVFLVAADAE----YALKVFDRRSHAPGXXXXXXXXXXWEV 183 DI+L R LG G G V LV + + +ALK + E Sbjct: 617 DINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMS---EK 673 Query: 184 SVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAEL 363 ++ + L + L M C GG+L + R + + F + RFY A + Sbjct: 674 EIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGN--FDDSTTRFYTACV 731 Query: 364 VSALADLHAAGIAYRDLKPEN 426 V A LH+ I YRDLKPEN Sbjct: 732 VEAFDYLHSRNIIYRDLKPEN 752
>RAN1_SCHPO (P08092) Negative regulator of sexual conjugation and meiosis (EC| 2.7.11.1) Length = 470 Score = 48.5 bits (114), Expect = 6e-06 Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 4/136 (2%) Frame = +1 Query: 31 SARAARVLGRGAMGTVFL---VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRL 201 S R ++G GA G V+ + YA+K + G E+++ +R+ Sbjct: 17 SLRFVSIIGAGAYGVVYKAEDIYDGTLYAVKALCK----DGLNEKQKKLQARELALHARV 72 Query: 202 A-HPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALA 378 + HP++ +L ET D + + YC GDL + + ++ +L+SA+ Sbjct: 73 SSHPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQLISAVE 132 Query: 379 DLHAAGIAYRDLKPEN 426 H+ GI +RDLKPEN Sbjct: 133 HCHSVGIYHRDLKPEN 148
>LATS2_HUMAN (Q9NRM7) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase) Length = 1088 Score = 48.5 bits (114), Expect = 6e-06 Identities = 39/130 (30%), Positives = 55/130 (42%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFL---VAADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG GA G V L V A YA+K ++ E +L+ + + Sbjct: 672 KTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKA---ERDILAEADNEWV 728 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L + D L + M Y GGD+ L VF RFY AEL A+ +H G Sbjct: 729 VKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRM--EVFPEHLARFYIAELTLAIESVHKMG 786 Query: 397 IAYRDLKPEN 426 +RD+KP+N Sbjct: 787 FIHRDIKPDN 796
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 48.5 bits (114), Expect = 6e-06 Identities = 41/141 (29%), Positives = 57/141 (40%), Gaps = 4/141 (2%) Frame = +1 Query: 16 DIDLPSARAARVLGRGAMGTVFLVAADAE----YALKVFDRRSHAPGXXXXXXXXXXWEV 183 DI+L R LG G G V LV + + +ALK + E Sbjct: 771 DINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMS---EK 827 Query: 184 SVLSRLAHPHLPSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAEL 363 ++ + L + L M C GG+L + R + + F + RFY A + Sbjct: 828 EIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGN--FDDSTTRFYTACV 885 Query: 364 VSALADLHAAGIAYRDLKPEN 426 V A LH+ I YRDLKPEN Sbjct: 886 VEAFDYLHSRNIIYRDLKPEN 906
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 48.1 bits (113), Expect = 8e-06 Identities = 42/129 (32%), Positives = 58/129 (44%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLG+G+ G V L + YA+K+ + ++++ + P L Sbjct: 343 VLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALMDK--PPFLT 400 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L +T D L + M Y GGDL Q + P AV FYAAE+ L LH GI Sbjct: 401 QLHSCFQTVDRLYFVMEYVNGGDLM-YHIQQVGKFKEPQAV-FYAAEISIGLFFLHKRGI 458 Query: 400 AYRDLKPEN 426 YRDLK +N Sbjct: 459 IYRDLKLDN 467
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 48.1 bits (113), Expect = 8e-06 Identities = 43/129 (33%), Positives = 57/129 (44%), Gaps = 3/129 (2%) Frame = +1 Query: 49 VLGRGAMGTVFLV---AADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHLP 219 VLG+G+ G V L + YA+K+ + +++L + P L Sbjct: 343 VLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDK--PPFLT 400 Query: 220 SLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAGI 399 L +T D L + M Y GGDL Q + P AV FYAAE+ L LH GI Sbjct: 401 QLHSCFQTVDRLYFVMEYVNGGDLM-YHIQQVGKFKEPQAV-FYAAEISIGLFFLHKRGI 458 Query: 400 AYRDLKPEN 426 YRDLK N Sbjct: 459 IYRDLKLNN 467
>LATS2_MOUSE (Q7TSJ6) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) Length = 1042 Score = 48.1 bits (113), Expect = 8e-06 Identities = 38/130 (29%), Positives = 54/130 (41%), Gaps = 3/130 (2%) Frame = +1 Query: 46 RVLGRGAMGTVFLVA---ADAEYALKVFDRRSHAPGXXXXXXXXXXWEVSVLSRLAHPHL 216 + LG GA G V L A YA+K ++ E +L+ + + Sbjct: 630 KTLGIGAFGEVCLACKLDTHALYAMKTLRKKDVLNRNQVAHVKA---ERDILAEADNEWV 686 Query: 217 PSLLGRAETPDLLAWAMPYCAGGDLNELRRAQPDRVFSPAAVRFYAAELVSALADLHAAG 396 L + D L + M Y GGD+ L VF RFY AEL A+ +H G Sbjct: 687 VKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRM--EVFPEHLARFYIAELTLAIESVHKMG 744 Query: 397 IAYRDLKPEN 426 +RD+KP+N Sbjct: 745 FIHRDIKPDN 754 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,134,206 Number of Sequences: 219361 Number of extensions: 604019 Number of successful extensions: 5496 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 3771 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5007 length of database: 80,573,946 effective HSP length: 101 effective length of database: 58,418,485 effective search space used: 2336739400 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
