>DHBE_BACSU (P40871) 2,3-dihydroxybenzoate-AMP ligase (EC 6.3.2.-)|
           (Dihydroxybenzoic acid-activating enzyme)
          Length = 539

 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 24/61 (39%), Positives = 35/61 (57%)
 Frame = +2

Query: 224 AAVYADRTSVICGGTAFTWRHTHDRCVRLSAALQALGVARNDVVSVLAPNTXALYEMHFA 403
           AA Y DR ++ CG T +++R    R  RL+A  Q LG+ + D V V  PN    +E+ FA
Sbjct: 35  AAKYGDRIAITCGNTHWSYRELDTRADRLAAGFQKLGIQQMDRVVVQLPNIKEFFEVIFA 94

Query: 404 V 406
           +
Sbjct: 95  L 95

>4CL3_ARATH (Q9S777) 4-coumarate--CoA ligase 3 (EC 6.2.1.12) (4CL 3) (At4CL3)|
           (4-coumaroyl-CoA synthase 3)
          Length = 561

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
 Frame = +2

Query: 149 IAMDSLPKRDA-NHVPLSPVTFLPRAAAVYADRTSVICGGT--AFTWRHTHDRCVRLSAA 319
           I    LP  D  NH+PL    F   ++   +D+  +I G T  ++T+  TH  C R+++ 
Sbjct: 34  IFRSKLPDIDIPNHLPLHTYCFEKLSSV--SDKPCLIVGSTGKSYTYGETHLICRRVASG 91

Query: 320 LQALGVARNDVVSVLAPNTXALYEMHFAVPMAG 418
           L  LG+ + DV+ +L  N+           M G
Sbjct: 92  LYKLGIRKGDVIMILLQNSAEFVFSFMGASMIG 124

>4CL2_SOYBN (P31687) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)|
           (4-coumaroyl-CoA synthase 2) (Clone 4CL16)
          Length = 562

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
 Frame = +2

Query: 179 ANHVPLSPVTFLPRAAAVYADRTSVICGGTA--FTWRHTHDRCVRLSAALQALGVARNDV 352
           +NH+PL    F  +  + +A R  +I G  +  FT+  TH    +++A L  LG+ + DV
Sbjct: 37  SNHLPLHSYCF--QNLSQFAHRPCLIVGPASKTFTYADTHLISSKIAAGLSNLGILKGDV 94

Query: 353 VSVLAPNTXALYEMHFAVPMAG 418
           V +L  N+        A+ M G
Sbjct: 95  VMILLQNSADFVFSFLAISMIG 116

>4CL2_ARATH (Q9S725) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (At4Cl2)|
           (4-coumaroyl-CoA synthase 2)
          Length = 556

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
 Frame = +2

Query: 182 NHVPLSPVTFLPRAAAVYADRTSVICG--GTAFTWRHTHDRCVRLSAALQALGVARNDVV 355
           NH+PL    F     + +A +  +I G  G  +T+   H    +L+A L  LGV ++DVV
Sbjct: 34  NHLPLHDYIF--ENISEFAAKPCLINGPTGEVYTYADVHVTSRKLAAGLHNLGVKQHDVV 91

Query: 356 SVLAPNT 376
            +L PN+
Sbjct: 92  MILLPNS 98

>4CL2_ORYSA (Q42982) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)|
           (4-coumaroyl-CoA synthase 2)
          Length = 569

 Score = 36.2 bits (82), Expect = 0.032
 Identities = 28/92 (30%), Positives = 35/92 (38%), Gaps = 1/92 (1%)
 Frame = +2

Query: 146 SIAMDSLPKRDA-NHVPLSPVTFLPRAAAVYADRTSVICGGTAFTWRHTHDRCVRLSAAL 322
           ++    LP  D  +H+PL    F   A    A        G  +T+  T   C R +AAL
Sbjct: 26  TVFRSKLPDIDIPSHLPLHEYCFARAAELPDAPCLIAAATGRTYTFAETRLLCRRAAAAL 85

Query: 323 QALGVARNDVVSVLAPNTXALYEMHFAVPMAG 418
             LGV   D V VL  N        FA    G
Sbjct: 86  HRLGVGHGDRVMVLLQNCVEFAVAFFAASFLG 117

>TYCC_BREPA (O30409) Tyrocidine synthetase 3 (Tyrocidine synthetase III)|
           [Includes: ATP-dependent asparagine adenylase (AsnA)
           (Asparagine activase); ATP-dependent glutamine adenylase
           (GlnA) (Glutamine activase); ATP-dependent tyrosine
           adenylase (TyrA) (Ty
          Length = 6486

 Score = 36.2 bits (82), Expect = 0.032
 Identities = 17/59 (28%), Positives = 33/59 (55%)
 Frame = +2

Query: 242 RTSVICGGTAFTWRHTHDRCVRLSAALQALGVARNDVVSVLAPNTXALYEMHFAVPMAG 418
           + +V+CG    T++   +R  +L+ AL+  G+A   +VS++A ++  L     AV  +G
Sbjct: 480 KAAVVCGEDTLTYQELMERSAQLANALREKGIASGSIVSIMAEHSLELIVAIMAVLRSG 538

>PPS2_BACSU (P39846) Peptide synthetase 2|
          Length = 2560

 Score = 34.7 bits (78), Expect = 0.094
 Identities = 15/54 (27%), Positives = 29/54 (53%)
 Frame = +2

Query: 203  VTFLPRAAAVYADRTSVICGGTAFTWRHTHDRCVRLSAALQALGVARNDVVSVL 364
            V+   +  A Y +  +V+CG +  T+R  +++  R +A L   GV   D+V ++
Sbjct: 1503 VSLFEKQVAQYPEHIAVVCGHSQLTYRDLNEKAERAAAMLIKQGVRTGDIVGLM 1556

>PABL_STRGR (P33585) Protein Y (ORF-3) (Fragment)|
          Length = 307

 Score = 33.9 bits (76), Expect = 0.16
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)
 Frame = +2

Query: 212 LPR--AAAVY--ADRTSVICGGTAFTWRHTHDRCVRLSAALQALGVARNDVVSVLAPNTX 379
           LPR  A AV+   D  +++ G  A TW         L+  LQ  GV   DVV++  PN+ 
Sbjct: 26  LPRVFADAVHRGGDAVALVDGEYALTWSAWRTAVDALARGLQESGVVSGDVVALHLPNSW 85

Query: 380 ALYEMHFAVPMAG 418
               +H A    G
Sbjct: 86  EYLTLHLAAASVG 98

>Y1549_MYCTU (Q10777) Hypothetical protein Rv1549/MT1599.1|
          Length = 175

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 17/53 (32%), Positives = 23/53 (43%)
 Frame = +2

Query: 260 GGTAFTWRHTHDRCVRLSAALQALGVARNDVVSVLAPNTXALYEMHFAVPMAG 418
           G    TWR    +  R++A L  LGV R D VS++  N    Y +       G
Sbjct: 64  GNQTMTWRDYAAQVRRVAAGLAGLGVRRGDTVSLMMANRIEFYPLDVGAQHVG 116

>LGRA_BREPA (Q70LM7) Linear gramicidin synthetase subunit A [Includes:|
            ATP-dependent valine/leucine adenylase (Val/LeuA)
            (Valine/leucine activase); ATP-dependent glycine
            adenylase (GlyA) (Glycine activase)]
          Length = 2273

 Score = 32.7 bits (73), Expect = 0.36
 Identities = 19/65 (29%), Positives = 35/65 (53%)
 Frame = +2

Query: 224  AAVYADRTSVICGGTAFTWRHTHDRCVRLSAALQALGVARNDVVSVLAPNTXALYEMHFA 403
            AA   D+T+++      T+R  ++R  +L+  L+  GV  +D+V ++A  +  +    FA
Sbjct: 1230 AAATPDKTALVFREQRVTYRELNERVNQLAHTLREKGVQPDDLVMLMAERSVEMMVAIFA 1289

Query: 404  VPMAG 418
            V  AG
Sbjct: 1290 VLKAG 1294

>4CL4_ARATH (Q9LU36) 4-coumarate--CoA ligase 4 (EC 6.2.1.12) (4CL 4) (At4CL4)|
           (4-coumaroyl-CoA synthase 4) (4-coumarate CoA ligase
           isoform 5)
          Length = 570

 Score = 32.3 bits (72), Expect = 0.47
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
 Frame = +2

Query: 182 NHVPLSPVTFLPRAAAVYADR--TSVICGGTA--FTWRHTHDRCVRLSAALQALGVARND 349
           NH+PL+   F   +     D   T +I G T    T+        R++A +  LG+   D
Sbjct: 40  NHLPLTDYVFQRFSGDGDGDSSTTCIIDGATGRILTYADVQTNMRRIAAGIHRLGIRHGD 99

Query: 350 VVSVLAPNTXALYEMHFAVPMAG 418
           VV +L PN+        AV   G
Sbjct: 100 VVMLLLPNSPEFALSFLAVAYLG 122

>4CL1_ARATH (Q42524) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1) (At4CL1)|
           (4-coumaroyl-CoA synthase 1)
          Length = 561

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
 Frame = +2

Query: 182 NHVPLSPVTFLPRAAAVYADRTSVICG--GTAFTWRHTHDRCVRLSAALQALGVARNDVV 355
           NH+ L    F  +  + +A +  +I G  G  +T+   H    +++A    LGV +NDVV
Sbjct: 36  NHLSLHDYIF--QNISEFATKPCLINGPTGHVYTYSDVHVISRQIAANFHKLGVNQNDVV 93

Query: 356 SVLAPN 373
            +L PN
Sbjct: 94  MLLLPN 99

>SRFAB_BACSU (Q04747) Surfactin synthetase subunit 2|
          Length = 3587

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 15/60 (25%), Positives = 29/60 (48%)
 Frame = +2

Query: 239  DRTSVICGGTAFTWRHTHDRCVRLSAALQALGVARNDVVSVLAPNTXALYEMHFAVPMAG 418
            D ++V  GG   T+R   ++  +L+  L+A G    D+V+++   +  +      V  AG
Sbjct: 1511 DHSAVKAGGNLLTYRELDEQANQLAHHLRAQGAGNEDIVAIVMDRSAEVMVSILGVMKAG 1570

>ACSA_XANAC (Q8PF09) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA|
           ligase) (Acyl-activating enzyme)
          Length = 647

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 7/63 (11%)
 Frame = +2

Query: 203 VTFLPRAAAVYADRTSVI-------CGGTAFTWRHTHDRCVRLSAALQALGVARNDVVSV 361
           V  L R  A   D+T+++             T+R  ++R  +L  AL+ LGV + D V++
Sbjct: 77  VNCLDRQLATRGDKTALLFEPDSPDAASYPVTYRELYERVCKLGNALRNLGVKKGDRVTI 136

Query: 362 LAP 370
             P
Sbjct: 137 YLP 139

>PRPE_ECOLI (P77495) Propionate--CoA ligase (EC 6.2.1.17) (Propionyl-CoA|
           synthetase)
          Length = 628

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 14/33 (42%), Positives = 20/33 (60%)
 Frame = +2

Query: 272 FTWRHTHDRCVRLSAALQALGVARNDVVSVLAP 370
           FT+R  HD    +++ L++LGV R D V V  P
Sbjct: 84  FTFRQLHDEVNAVASMLRSLGVQRGDRVLVYMP 116

>SYV_GLOVI (Q7NCQ9) Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase)|
           (ValRS)
          Length = 897

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 21/73 (28%), Positives = 34/73 (46%)
 Frame = -1

Query: 288 VWRQVKAVPPQMTEVRSA*TAAARGRKVTGLSGTWLASRLGKLSMAIDQKLIDSSRVKDQ 109
           +W   + V   + E+  A   AA    +T L   W+  RLG+ +  ID+ L+    + + 
Sbjct: 594 IWNASRFVLMNLDELTPAALGAADPGSLT-LEDRWILGRLGQTARQIDE-LLGRYALGEA 651

Query: 108 ARSMGGLIRSDVC 70
           ARS+   I  D C
Sbjct: 652 ARSLYEFIWDDFC 664

>4CL1_TOBAC (O24145) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)|
           (4-coumaroyl-CoA synthase 1)
          Length = 547

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 16/66 (24%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
 Frame = +2

Query: 185 HVPLSPVTFLPRAAAVYADRTSVICGGT--AFTWRHTHDRCVRLSAALQALGVARNDVVS 358
           H+PL    F     + ++ R  +I G     +T+      C +++  L  LG+ + D + 
Sbjct: 29  HLPLHSYCF--ENISEFSSRPCLINGANDQIYTYAEVELTCRKVAVGLNKLGIQQKDTIM 86

Query: 359 VLAPNT 376
           +L PN+
Sbjct: 87  ILLPNS 92

>ACSA_NOSLI (Q93LL2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA|
           ligase) (Acyl-activating enzyme) (Fragment)
          Length = 337

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 6/59 (10%)
 Frame = +2

Query: 212 LPRAAAVYADRTSVICGG------TAFTWRHTHDRCVRLSAALQALGVARNDVVSVLAP 370
           L R  A   D+ ++I  G      +  T+R  H R  +L+ A++ +GV + D V +  P
Sbjct: 22  LDRHLATRGDQVAIIWEGDDPNADSKVTYRELHARVCQLANAMRGMGVQKGDRVCIYLP 80

>METK_PICTO (Q6L123) S-adenosylmethionine synthetase (EC 2.5.1.6) (Methionine|
           adenosyltransferase) (AdoMet synthetase)
          Length = 402

 Score = 28.9 bits (63), Expect = 5.2
 Identities = 15/29 (51%), Positives = 18/29 (62%)
 Frame = -3

Query: 403 REVHLVERXGVGREHGDDVVPGNAERLQR 317
           REV +VER G+G  H D V  G AE + R
Sbjct: 22  REVEIVERKGIG--HPDSVADGIAEAVSR 48

>ACSA_YERPE (Q8D1G8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA|
           ligase) (Acyl-activating enzyme)
          Length = 652

 Score = 28.9 bits (63), Expect = 5.2
 Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 6/59 (10%)
 Frame = +2

Query: 212 LPRAAAVYADRTSVICGGT------AFTWRHTHDRCVRLSAALQALGVARNDVVSVLAP 370
           L R  A   D+T++I  G         T++  H    + +  L++LGV + DVV++  P
Sbjct: 82  LDRHLAERGDQTAIIWEGDDPNQSKTVTYKQLHHDVCQFANVLKSLGVKKGDVVAIYMP 140

>ACSA_XANCP (Q8P3L1) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA|
           ligase) (Acyl-activating enzyme)
          Length = 647

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
 Frame = +2

Query: 203 VTFLPRAAAVYADRTSVICGGTA-------FTWRHTHDRCVRLSAALQALGVARNDVVSV 361
           V  L R  A   D+T+++    +        T+R  ++R  +L  AL+ LGV + D V++
Sbjct: 77  VNCLDRQLATRGDKTALLFEPDSPDSPSYPVTYRELYERVCKLGNALRNLGVKKGDRVTI 136

Query: 362 LAP 370
             P
Sbjct: 137 YLP 139

>ACSA_RALSO (Q8XY11) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA|
           ligase) (Acyl-activating enzyme)
          Length = 660

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
 Frame = +2

Query: 236 ADRTSVIC----GGTA-FTWRHTHDRCVRLSAALQALGVARNDVVSVLAP 370
           AD+ +VI     G  A  T+R  H R  R +  L+ALG+ + D V +  P
Sbjct: 97  ADKVAVIFEADDGSVARITYRELHARVCRFANGLKALGIRKGDRVVIYMP 146

>ACSA_XYLFT (Q87C00) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA|
           ligase) (Acyl-activating enzyme)
          Length = 647

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 16/63 (25%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
 Frame = +2

Query: 203 VTFLPRAAAVYADRTSVI-------CGGTAFTWRHTHDRCVRLSAALQALGVARNDVVSV 361
           V  L R   +  D+T+++          +  T+R  ++R  +L  AL+ LG+ + D V++
Sbjct: 77  VNCLDRHLTLRGDKTALLFEPDAPDAPSSRITYRELYERVCQLGNALRHLGIEKGDRVTI 136

Query: 362 LAP 370
             P
Sbjct: 137 YLP 139

>4CL2_PETCR (P14913) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)|
           (4-coumaroyl-CoA synthase 1)
          Length = 544

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 16/66 (24%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
 Frame = +2

Query: 185 HVPLSPVTFLPRAAAVYADRTSVICGGTAFTWRHTHDRCV--RLSAALQALGVARNDVVS 358
           H+PL    F     +   D++ +I G T  T+ ++    +  ++++ L  LG+ + D + 
Sbjct: 25  HLPLHTYCF--ENISKVGDKSCLINGATGETFTYSQVELLSRKVASGLNKLGIQQGDTIM 82

Query: 359 VLAPNT 376
           +L PN+
Sbjct: 83  LLLPNS 88

>4CL1_PETCR (P14912) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)|
           (4-coumaroyl-CoA synthase 1)
          Length = 544

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 16/66 (24%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
 Frame = +2

Query: 185 HVPLSPVTFLPRAAAVYADRTSVICGGTAFTWRHTHDRCV--RLSAALQALGVARNDVVS 358
           H+PL    F     +   D++ +I G T  T+ ++    +  ++++ L  LG+ + D + 
Sbjct: 25  HLPLHTYCF--ENISKVGDKSCLINGATGETFTYSQVELLSRKVASGLNKLGIQQGDTIM 82

Query: 359 VLAPNT 376
           +L PN+
Sbjct: 83  LLLPNS 88

>MENE_BACC1 (Q72YK9) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA|
           synthetase) (o-succinylbenzoyl-CoA synthetase)
          Length = 481

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 18/70 (25%), Positives = 32/70 (45%)
 Frame = +2

Query: 209 FLPRAAAVYADRTSVICGGTAFTWRHTHDRCVRLSAALQALGVARNDVVSVLAPNTXALY 388
           +L + A +  DRT++       T+   H++ V +   L  +GV R   V+VL  N   + 
Sbjct: 7   WLMQRAFLTPDRTAIEIEEEKVTFMQLHEKVVSVCEHLTHIGVKRGQKVAVLMKNGMEMI 66

Query: 389 EMHFAVPMAG 418
            +  A+   G
Sbjct: 67  TVIHALSYVG 76

>ACSA_RALEU (P31638) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA|
           ligase) (Acyl-activating enzyme)
          Length = 660

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 12/35 (34%), Positives = 19/35 (54%)
 Frame = +2

Query: 266 TAFTWRHTHDRCVRLSAALQALGVARNDVVSVLAP 370
           T  T+R  H +  R +  L+ALG+ + D V +  P
Sbjct: 112 TRVTYRELHGKVCRFANGLKALGIRKGDRVVIYMP 146

>MENE_BACHK (Q6HC29) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA|
           synthetase) (o-succinylbenzoyl-CoA synthetase)
          Length = 482

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 18/70 (25%), Positives = 32/70 (45%)
 Frame = +2

Query: 209 FLPRAAAVYADRTSVICGGTAFTWRHTHDRCVRLSAALQALGVARNDVVSVLAPNTXALY 388
           +L + A +  DRT++       T+   H++ V +   L  +GV R   V+VL  N   + 
Sbjct: 8   WLKQRAFLTPDRTAIEIEEEKVTFMQLHEKVVSVCEHLTHVGVKRGQKVAVLMKNGMEMI 67

Query: 389 EMHFAVPMAG 418
            +  A+   G
Sbjct: 68  TVIHALSYVG 77


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,955,299
Number of Sequences: 219361
Number of extensions: 806993
Number of successful extensions: 2245
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 2204
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2245
length of database: 80,573,946
effective HSP length: 100
effective length of database: 58,637,846
effective search space used: 2286875994
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)