ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bast12d07 |
|---|---|
| Clone Library Name | barley_pub |
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 110 bits (274), Expect = 1e-24 Identities = 51/92 (55%), Positives = 70/92 (76%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKK-VKLD 179 G REF E+ET+G I+HRNLV L G+ + LL Y++M+ GSL D+LH P K VKL+ Sbjct: 920 GDREFMAEMETIGKIKHRNLVPLLGYCKVGDERLLVYEFMKYGSLEDVLHDPKKAGVKLN 979 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W TR +IA+G+A+GLA+LHH+C+P I+HRD+K Sbjct: 980 WSTRRKIAIGSARGLAFLHHNCSPHIIHRDMK 1011
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 106 bits (264), Expect = 2e-23 Identities = 51/87 (58%), Positives = 66/87 (75%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E++T+G IRHR++V L G+ + + NLL Y+YM NGSL +LLHG SK L W+TR Sbjct: 734 FTAEIQTLGRIRHRHIVRLLGYVANKDTNLLLYEYMPNGSLGELLHG-SKGGHLQWETRH 792 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 R+AV AA+GL YLHHDC+P I+HRDVK Sbjct: 793 RVAVEAAKGLCYLHHDCSPLILHRDVK 819
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 106 bits (264), Expect = 2e-23 Identities = 50/91 (54%), Positives = 60/91 (65%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDW 182 G+ E+ET+G +RHRNL+ L F L L+ Y YMENGSL D+LH + LDW Sbjct: 854 GSVSMVREIETIGKVRHRNLIKLEEFWLRKEYGLILYTYMENGSLHDILHETNPPKPLDW 913 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 TR IAVG A GLAYLH DC+P IVHRD+K Sbjct: 914 STRHNIAVGTAHGLAYLHFDCDPAIVHRDIK 944
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 105 bits (261), Expect = 4e-23 Identities = 50/92 (54%), Positives = 66/92 (71%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKK-VKLD 179 G REF E+ET+G I+HRNLV L G+ LL Y+YM+ GSL D+LH K +KL+ Sbjct: 925 GDREFTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYGSLEDVLHDRKKTGIKLN 984 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W R +IA+GAA+GLA+LHH+C P I+HRD+K Sbjct: 985 WPARRKIAIGAARGLAFLHHNCIPHIIHRDMK 1016
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 104 bits (260), Expect = 5e-23 Identities = 50/92 (54%), Positives = 66/92 (71%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSK-KVKLD 179 G REF E+ET+G I+HRNLV L G+ LL Y+YM+ GSL D+LH K +KL+ Sbjct: 925 GDREFTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYGSLEDVLHDRKKIGIKLN 984 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W R +IA+GAA+GLA+LHH+C P I+HRD+K Sbjct: 985 WPARRKIAIGAARGLAFLHHNCIPHIIHRDMK 1016
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 103 bits (256), Expect = 1e-22 Identities = 50/93 (53%), Positives = 65/93 (69%), Gaps = 2/93 (2%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKK--VKL 176 G REF E+ET+G I+HRNLV L G+ LL Y+YM+ GSL +LH +KK + L Sbjct: 895 GDREFMAEMETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKYGSLETVLHEKTKKGGIFL 954 Query: 177 DWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 DW R +IA+GAA+GLA+LHH C P I+HRD+K Sbjct: 955 DWSARKKIAIGAARGLAFLHHSCIPHIIHRDMK 987
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 99.0 bits (245), Expect = 3e-21 Identities = 48/94 (51%), Positives = 65/94 (69%), Gaps = 3/94 (3%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGP---SKKVK 173 G REF E+ET+G I+HRNLV L G+ LL Y++M+ GSL ++LHGP K+ Sbjct: 875 GDREFMAEMETLGKIKHRNLVPLLGYCKIGEERLLVYEFMQYGSLEEVLHGPRTGEKRRI 934 Query: 174 LDWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 L W+ R +IA GAA+GL +LHH+C P I+HRD+K Sbjct: 935 LGWEERKKIAKGAAKGLCFLHHNCIPHIIHRDMK 968
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 99.0 bits (245), Expect = 3e-21 Identities = 49/94 (52%), Positives = 64/94 (68%), Gaps = 3/94 (3%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKK---VK 173 G REF E+ET+G I+HRNLV L G+ LL Y+YM+ GSL +LH S K + Sbjct: 896 GDREFMAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKWGSLETVLHEKSSKKGGIY 955 Query: 174 LDWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 L+W R +IA+GAA+GLA+LHH C P I+HRD+K Sbjct: 956 LNWAARKKIAIGAARGLAFLHHSCIPHIIHRDMK 989
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 98.2 bits (243), Expect = 5e-21 Identities = 51/88 (57%), Positives = 63/88 (71%), Gaps = 1/88 (1%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKK-VKLDWDTR 191 F E+ET+G+IRH+++V L S + LL Y+YM NGSL D+LHG K V L W R Sbjct: 734 FAAEVETLGTIRHKSIVRLWCCCSSGDCKLLVYEYMPNGSLADVLHGDRKGGVVLGWPER 793 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 LRIA+ AA+GL+YLHHDC P IVHRDVK Sbjct: 794 LRIALDAAEGLSYLHHDCVPPIVHRDVK 821
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 96.7 bits (239), Expect = 1e-20 Identities = 52/93 (55%), Positives = 60/93 (64%), Gaps = 4/93 (4%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH----GPSKKVKL 176 REFE E+ET+ +H NLV L GF N LL Y YMENGSL LH GP+ L Sbjct: 773 REFEAEVETLSRAQHPNLVLLRGFCFYKNDRLLIYSYMENGSLDYWLHERNDGPAL---L 829 Query: 177 DWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W TRLRIA GAA+GL YLH C+P I+HRD+K Sbjct: 830 KWKTRLRIAQGAAKGLLYLHEGCDPHILHRDIK 862
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 95.9 bits (237), Expect = 2e-20 Identities = 51/93 (54%), Positives = 60/93 (64%), Gaps = 4/93 (4%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH----GPSKKVKL 176 REF+ E+ET+ +H NLV L G+ N LL Y YM+NGSL LH GP L Sbjct: 782 REFQAEVETLSRAQHPNLVHLLGYCNYKNDKLLIYSYMDNGSLDYWLHEKVDGPPS---L 838 Query: 177 DWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 DW TRLRIA GAA+GLAYLH C P I+HRD+K Sbjct: 839 DWKTRLRIARGAAEGLAYLHQSCEPHILHRDIK 871
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 95.9 bits (237), Expect = 2e-20 Identities = 46/92 (50%), Positives = 61/92 (66%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG-PSKKVKLD 179 G +F+TE+E + HRNL+ L GF ++P LL Y YM NGS+ L P + LD Sbjct: 327 GELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCLRERPESQPPLD 386 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W R RIA+G+A+GLAYLH C+P+I+HRDVK Sbjct: 387 WPKRQRIALGSARGLAYLHDHCDPKIIHRDVK 418
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 94.4 bits (233), Expect = 7e-20 Identities = 48/92 (52%), Positives = 62/92 (67%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVK-LD 179 G REF E+ET+G ++H NLVSL G+ LL Y+YM NGSL L + ++ LD Sbjct: 954 GNREFMAEMETLGKVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSLDHWLRNQTGMLEVLD 1013 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W RL+IAVGAA+GLA+LHH P I+HRD+K Sbjct: 1014 WSKRLKIAVGAARGLAFLHHGFIPHIIHRDIK 1045
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 91.7 bits (226), Expect = 4e-19 Identities = 47/92 (51%), Positives = 62/92 (67%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG-PSKKVKLD 179 G REF+ EL + +I+H NLV L G+ + +L Y +M NGSL D L+G P+K+ LD Sbjct: 632 GTREFDNELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLYGEPAKRKILD 691 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W TRL IA+GAA+GLAYLH ++HRDVK Sbjct: 692 WPTRLSIALGAARGLAYLHTFPGRSVIHRDVK 723
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 90.5 bits (223), Expect = 1e-18 Identities = 47/92 (51%), Positives = 61/92 (66%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVK-LD 179 G REF+ EL + +I+H NLV L G+ + +L Y +M NGSL D L+G + K K LD Sbjct: 633 GTREFDNELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLYGEASKRKILD 692 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W TRL IA+GAA+GLAYLH ++HRDVK Sbjct: 693 WPTRLSIALGAARGLAYLHTFPGRSVIHRDVK 724
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 87.8 bits (216), Expect = 6e-18 Identities = 41/91 (45%), Positives = 56/91 (61%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDW 182 G F+ EL +G I H NLV + GF + LL +Y+ENGSL ++L + LDW Sbjct: 570 GKEVFQAELSVIGRINHMNLVRIWGFCSEGSHRLLVSEYVENGSLANILFSEGGNILLDW 629 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + R IA+G A+GLAYLHH+C ++H DVK Sbjct: 630 EGRFNIALGVAKGLAYLHHECLEWVIHCDVK 660
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 86.7 bits (213), Expect = 1e-17 Identities = 46/92 (50%), Positives = 58/92 (63%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG-PSKKVKLD 179 G REF E+ T+ H NLV L GF + LL Y+YM GSL D LH PS K LD Sbjct: 141 GIREFVVEVLTLSLADHPNLVKLIGFCAEGDQRLLVYEYMPQGSLEDHLHVLPSGKKPLD 200 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W+TR++IA GAA+GL YLH P +++RD+K Sbjct: 201 WNTRMKIAAGAARGLEYLHDRMTPPVIYRDLK 232
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 83.2 bits (204), Expect = 2e-16 Identities = 42/91 (46%), Positives = 57/91 (62%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDW 182 G +EF E++ + + H NL SL G+ N +L Y+YM N +L D L G + L W Sbjct: 610 GYKEFRAEVDLLMRVHHTNLTSLVGYCNEINHMVLIYEYMANENLGDYLAGKRSFI-LSW 668 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + RL+I++ AAQGL YLH+ C P IVHRDVK Sbjct: 669 EERLKISLDAAQGLEYLHNGCKPPIVHRDVK 699
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 79.7 bits (195), Expect = 2e-15 Identities = 41/92 (44%), Positives = 57/92 (61%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG-PSKKVKLD 179 G REF E+ + + H NLV+L G+ + LL Y++M GSL D LH P K LD Sbjct: 124 GNREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEFMPLGSLEDHLHDLPPDKEALD 183 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W+ R++IA GAA+GL +LH NP +++RD K Sbjct: 184 WNMRMKIAAGAAKGLEFLHDKANPPVIYRDFK 215
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 77.4 bits (189), Expect = 9e-15 Identities = 37/92 (40%), Positives = 60/92 (65%), Gaps = 2/92 (2%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG--PSKKVKLD 179 ++EF EL+ + + H +L++L G+ + LL Y++M +GSL+ LHG P+ K +L+ Sbjct: 545 SKEFHNELDLLSRLNHAHLLNLLGYCEDGSERLLVYEFMAHGSLYQHLHGKDPNLKKRLN 604 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W R+ IAV AA+G+ YLH P ++HRD+K Sbjct: 605 WARRVTIAVQAARGIEYLHGYACPPVIHRDIK 636
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 77.0 bits (188), Expect = 1e-14 Identities = 37/91 (40%), Positives = 55/91 (60%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDW 182 G EF E+ + ++H NLV + G + + +L Y+Y+EN SL L G +++ KL+W Sbjct: 565 GTDEFMNEVTLIARLQHINLVQVLGCCIEGDEKMLIYEYLENLSLDSYLFGKTRRSKLNW 624 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + R I G A+GL YLH D RI+HRD+K Sbjct: 625 NERFDITNGVARGLLYLHQDSRFRIIHRDLK 655
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 70.9 bits (172), Expect = 8e-13 Identities = 38/92 (41%), Positives = 58/92 (63%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWD-LLHGPSKKVKLD 179 G RE+ E+ +G + H NLV L G+ L LL Y++M GSL + L + L Sbjct: 115 GHREWLAEINYLGQLDHPNLVKLIGYCLEEEHRLLVYEFMTRGSLENHLFRRGTFYQPLS 174 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W+TR+R+A+GAA+GLA+L H+ P++++RD K Sbjct: 175 WNTRVRMALGAARGLAFL-HNAQPQVIYRDFK 205
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 67.4 bits (163), Expect = 9e-12 Identities = 38/85 (44%), Positives = 50/85 (58%), Gaps = 2/85 (2%) Frame = +3 Query: 27 LETVGSIRHRNLVSLHGFSLSPNGN-LLFYDYMENGSLWDLLH-GPSKKVKLDWDTRLRI 200 + +G IRH NLV L F G LL YDY+ N SL DLLH +K L+W R +I Sbjct: 418 IRQLGRIRHENLVPLRAFYQGKRGEKLLIYDYLPNISLHDLLHESKPRKPALNWARRHKI 477 Query: 201 AVGAAQGLAYLHHDCNPRIVHRDVK 275 A+G A+GLAYLH I+H +++ Sbjct: 478 ALGIARGLAYLHTGQEVPIIHGNIR 502
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 67.0 bits (162), Expect = 1e-11 Identities = 34/89 (38%), Positives = 51/89 (57%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 ++F+ E++ + + +H NLV L GFS + L Y YM NGSL D L L W T Sbjct: 228 QQFDQEIKVMATCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRLSCLDGTPPLSWHT 287 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 R ++A G A G+ +LH + + +HRD+K Sbjct: 288 RCKVAQGTANGIRFLHENHH---IHRDIK 313
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 65.5 bits (158), Expect = 3e-11 Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 2/93 (2%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKK--VKL 176 G EF++E+ + +RHR+LV+L G+ L N LL Y+YM G+L L S++ L Sbjct: 627 GFAEFKSEIAVLTKVRHRHLVTLLGYCLDGNEKLLVYEYMPQGTLSRHLFEWSEEGLKPL 686 Query: 177 DWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W RL +A+ A+G+ YLH + +HRD+K Sbjct: 687 LWKQRLTLALDVARGVEYLHGLAHQSFIHRDLK 719
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 64.7 bits (156), Expect = 6e-11 Identities = 35/89 (39%), Positives = 50/89 (56%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 ++F+ E++ + +H NLV L GFS + L Y YM NGSL D L L W Sbjct: 228 QQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHM 287 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 R +IA GAA G+ +LH + + +HRD+K Sbjct: 288 RCKIAQGAANGINFLHENHH---IHRDIK 313
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 64.3 bits (155), Expect = 8e-11 Identities = 36/92 (39%), Positives = 54/92 (58%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVK-LD 179 G +E+ E+ +G HR+LV L G+ L LL Y++M GSL + L + L Sbjct: 115 GHQEWLAEVNYLGQFSHRHLVKLIGYCLEDEHRLLVYEFMPRGSLENHLFRRGLYFQPLS 174 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W RL++A+GAA+GLA+L H R+++RD K Sbjct: 175 WKLRLKVALGAAKGLAFL-HSSETRVIYRDFK 205
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 63.5 bits (153), Expect = 1e-10 Identities = 36/92 (39%), Positives = 53/92 (57%), Gaps = 1/92 (1%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWD-LLHGPSKKVKLD 179 G +E+ E+ +G H NLV L G+ L LL Y++M GSL + L S L Sbjct: 116 GHQEWLAEVNYLGQFSHPNLVKLIGYCLEDEHRLLVYEFMPRGSLENHLFRRGSYFQPLS 175 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W RL++A+GAA+GLA+L H+ +++RD K Sbjct: 176 WTLRLKVALGAAKGLAFL-HNAETSVIYRDFK 206
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 62.4 bits (150), Expect = 3e-10 Identities = 34/91 (37%), Positives = 51/91 (56%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDW 182 G E+ +E+ +G + HRNLV L G+ LL Y++M GSL H + W Sbjct: 133 GFAEWRSEVNFLGMLSHRNLVKLLGYCREDKELLLVYEFMPKGSLES--HLFRRNDPFPW 190 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 D R++I +GAA+GLA+L H +++RD K Sbjct: 191 DLRIKIVIGAARGLAFL-HSLQREVIYRDFK 220
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 61.2 bits (147), Expect = 6e-10 Identities = 31/88 (35%), Positives = 50/88 (56%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 EF E+ + ++H N+V+ G + + +YM G+L D+L P +K+ + + Sbjct: 1405 EFRAEMAFLSELKHSNIVTFIGACIKKPNICIVTEYMRMGNLRDVLKNPD--IKITFANK 1462 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 L++ GAA G+ YL H NP IVHRD+K Sbjct: 1463 LKLLYGAAMGIDYL-HSSNPMIVHRDIK 1489 Score = 45.4 bits (106), Expect = 4e-05 Identities = 28/89 (31%), Positives = 50/89 (56%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R F E++ + S+RH N+V S + ++M GSL+DLL G ++ + Sbjct: 826 RSFFEEVKIMTSLRHPNVVLFMAASTKSPNMCIVMEFMSLGSLYDLL-GNELIPEIPYAL 884 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 ++++A A++G+ +LH + IVHRD+K Sbjct: 885 KIKMAYQASKGMHFLH---SSGIVHRDLK 910
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 60.5 bits (145), Expect = 1e-09 Identities = 32/90 (35%), Positives = 49/90 (54%), Gaps = 1/90 (1%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKV-KLDWD 185 + F TE+E + RH N+V G+ L Y ++ NGSL D LH ++ L W Sbjct: 254 QSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWP 313 Query: 186 TRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 RL I +G A+ + +LH D +P ++H D+K Sbjct: 314 QRLDILLGTARAIQFLHQD-SPSLIHGDIK 342
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 60.5 bits (145), Expect = 1e-09 Identities = 32/90 (35%), Positives = 49/90 (54%), Gaps = 1/90 (1%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVK-LDWD 185 + F TE+E + RH N+V G+ L Y ++ NGSL D LH ++ L W Sbjct: 254 QSFLTEVEQLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLHLQTQACSPLSWP 313 Query: 186 TRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 RL I +G A+ + +LH D +P ++H D+K Sbjct: 314 QRLDILLGTARAIQFLHQD-SPSLIHGDIK 342
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 60.1 bits (144), Expect = 1e-09 Identities = 34/88 (38%), Positives = 49/88 (55%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 EF E+ + +RH N+V G P + +Y+ GSL+ LLH + +LD R Sbjct: 592 EFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKSGAREQLDERRR 651 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 L +A A+G+ YLH+ NP IVHRD+K Sbjct: 652 LSMAYDVAKGMNYLHNR-NPPIVHRDLK 678
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 57.0 bits (136), Expect = 1e-08 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 2/91 (2%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 ++ E E++ + ++H N+++LHG S L ++ E GSL + LHG KVK + Sbjct: 55 KDIEKEVKQLSRVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFLHG---KVKPAYSL 111 Query: 189 --RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + A A+GLAYLH ++HRDVK Sbjct: 112 AHAMSWARQCAEGLAYLHAMTPKPLIHRDVK 142
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 55.1 bits (131), Expect = 5e-08 Identities = 26/88 (29%), Positives = 49/88 (55%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 + E E E + + HRN++ +G L P + +Y GSL+D ++ ++ ++D D Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINS-NRSEEMDMDHI 107 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + A A+G+ YLH + +++HRD+K Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLK 135
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 54.3 bits (129), Expect = 8e-08 Identities = 29/87 (33%), Positives = 47/87 (54%), Gaps = 3/87 (3%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKK---VKLDWDTRL 194 EL+ + SIRH N+++L+G+S+ L Y M+ GSL L + L W R Sbjct: 262 ELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQQRF 321 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 I++G A+G+ +LH ++H D+K Sbjct: 322 SISLGTARGIYFLHTARGTPLIHGDIK 348
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 53.5 bits (127), Expect = 1e-07 Identities = 25/88 (28%), Positives = 49/88 (55%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 + E E E + + HRN++ +G L P + +Y GSL+D ++ ++ ++D + Sbjct: 49 KIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINS-NRSEEMDMEHI 107 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + A A+G+ YLH + +++HRD+K Sbjct: 108 MTWATDVAKGMHYLHMEAPVKVIHRDLK 135
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 51.6 bits (122), Expect = 5e-07 Identities = 29/89 (32%), Positives = 46/89 (51%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 + F EL + + H N+V L+G L+P L +Y E GSL+++LHG Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLHGAEPLPYYTAAH 129 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + + +QG+AYLH ++HRD+K Sbjct: 130 AMSWCLQCSQGVAYLHSMQPKALIHRDLK 158
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 51.6 bits (122), Expect = 5e-07 Identities = 29/89 (32%), Positives = 46/89 (51%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 + F EL + + H N+V L+G L+P L +Y E GSL+++LHG Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLHGAEPLPYYTAAH 129 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + + +QG+AYLH ++HRD+K Sbjct: 130 AMSWCLQCSQGVAYLHSMQPKALIHRDLK 158
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 51.2 bits (121), Expect = 7e-07 Identities = 24/77 (31%), Positives = 40/77 (51%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 + F +ELE + RH +++ L + L Y YM NG+L+D L + L W Sbjct: 220 KRFLSELEVLLLFRHPHILELAAYFTETEKLCLVYPYMSNGTLFDRLQCTNGTTPLSWHV 279 Query: 189 RLRIAVGAAQGLAYLHH 239 R+ + +G A+ + YLH+ Sbjct: 280 RISVLIGIAKAIQYLHN 296
>LIMK2_RAT (P53670) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 50.1 bits (118), Expect = 1e-06 Identities = 29/88 (32%), Positives = 44/88 (50%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 + F TE++ + S+ H N++ G L +Y+E G+L D L W Sbjct: 371 KTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRNVDP---FPWQQ 427 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 ++R A G A G+AYLH C I+HRD+ Sbjct: 428 KVRFAKGIASGMAYLHSMC---IIHRDL 452
>LIMK2_HUMAN (P53671) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 50.1 bits (118), Expect = 1e-06 Identities = 29/88 (32%), Positives = 44/88 (50%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 + F TE++ + S+ H N++ G L +Y+E G+L D L W Sbjct: 371 KTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDP---FPWQQ 427 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 ++R A G A G+AYLH C I+HRD+ Sbjct: 428 KVRFAKGIASGMAYLHSMC---IIHRDL 452
>BMR1A_MOUSE (P36895) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) Length = 532 Score = 49.3 bits (116), Expect = 3e-06 Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGN----LLFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETE+ +RH N++ + G+ L DY ENGSL+D L K LD Sbjct: 274 ETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFL----KCATLDTR 329 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 L++A AA GL +LH + P I HRD+K Sbjct: 330 ALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLK 364
>BMR1A_HUMAN (P36894) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen) Length = 532 Score = 49.3 bits (116), Expect = 3e-06 Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGN----LLFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETE+ +RH N++ + G+ L DY ENGSL+D L K LD Sbjct: 274 ETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFL----KCATLDTR 329 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 L++A AA GL +LH + P I HRD+K Sbjct: 330 ALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLK 364
>BMR1B_MOUSE (P36898) Bone morphogenetic protein receptor type IB precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6) Length = 502 Score = 49.3 bits (116), Expect = 3e-06 Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGN----LLFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETE+ +RH N++ + G+ L DY ENGSL+D L K LD Sbjct: 244 ETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYL----KSTTLDAK 299 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 + L++A + GL +LH + P I HRD+K Sbjct: 300 SMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLK 334
>BMR1B_HUMAN (O00238) Bone morphogenetic protein receptor type IB precursor (EC| 2.7.11.30) (CDw293 antigen) Length = 502 Score = 49.3 bits (116), Expect = 3e-06 Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGN----LLFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETE+ +RH N++ + G+ L DY ENGSL+D L K LD Sbjct: 244 ETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYL----KSTTLDAK 299 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 + L++A + GL +LH + P I HRD+K Sbjct: 300 SMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLK 334
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 48.9 bits (115), Expect = 3e-06 Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 4/92 (4%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLL--HGPSKKVKLDW 182 ++F+ E+E + ++H+N+V + G L+ + ++YM NG L + L + P++ L Sbjct: 454 QDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQ 513 Query: 183 DTRLRIAVGAAQGLAYL--HHDCNPRIVHRDV 272 L+IA+ ++G+ YL HH VHRD+ Sbjct: 514 LEFLQIALQISEGMQYLSAHH-----YVHRDL 540
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 48.9 bits (115), Expect = 3e-06 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 2/86 (2%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPS--KKVKLDWDTRLR 197 E G+++H N+++L G L+P L +Y G+L +L G V ++W Sbjct: 145 EARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNW----- 199 Query: 198 IAVGAAQGLAYLHHDCNPRIVHRDVK 275 AV A+G+ YLH+D I+HRD+K Sbjct: 200 -AVQVARGMNYLHNDAPVPIIHRDLK 224
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 48.9 bits (115), Expect = 3e-06 Identities = 24/77 (31%), Positives = 38/77 (49%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 + F +ELE + H N++ L + L Y YM NG+L+D L L W Sbjct: 207 KRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHI 266 Query: 189 RLRIAVGAAQGLAYLHH 239 R+ I +G ++ + YLH+ Sbjct: 267 RIGILIGISKAIHYLHN 283
>LIMK2_MOUSE (O54785) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 48.9 bits (115), Expect = 3e-06 Identities = 28/88 (31%), Positives = 44/88 (50%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 + F TE++ + S+ H N++ G L +Y+E G+L D L W Sbjct: 371 KTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSVDP---FPWQQ 427 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 ++R A G + G+AYLH C I+HRD+ Sbjct: 428 KVRFAKGISSGMAYLHSMC---IIHRDL 452
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 48.5 bits (114), Expect = 4e-06 Identities = 30/89 (33%), Positives = 41/89 (46%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R F+ EL+ H N++ + GF + + Y YM NGSL D L G L W Sbjct: 252 RFFQAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQGGSDPLPWPQ 311 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 R+ I G + YLH I+H +VK Sbjct: 312 RVSICSGLLCAVEYLH---GLEIIHSNVK 337
>LIMK2_CHICK (P53666) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 642 Score = 48.1 bits (113), Expect = 6e-06 Identities = 28/88 (31%), Positives = 43/88 (48%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 + F TE++ + S+ H N++ G L +Y+E G+L D L W Sbjct: 371 KTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRNADP---FPWQQ 427 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 ++ A G A G+AYLH C I+HRD+ Sbjct: 428 KVSFAKGIASGMAYLHSMC---IIHRDL 452
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 48.1 bits (113), Expect = 6e-06 Identities = 30/86 (34%), Positives = 48/86 (55%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLR 197 E E+ + I H N++ + G + + + L +Y+E GSL + L+G K + + +R Sbjct: 52 EREITHLSEIDHENVIRVIGRASNGKKDYLLMEYLEEGSLHNYLYG-DDKWEYTVEQAVR 110 Query: 198 IAVGAAQGLAYLHHDCNPRIVHRDVK 275 A+ A+ LAYLH P IVHRD+K Sbjct: 111 WALQCAKALAYLHSLDRP-IVHRDIK 135
>RIPK2_MOUSE (P58801) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 539 Score = 47.4 bits (111), Expect = 1e-05 Identities = 28/84 (33%), Positives = 43/84 (51%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E E + R ++ + G P + +YM NGSL +LLH ++ + W R RI Sbjct: 66 EAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDIAWPLRFRIL 125 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 A G+ YL H+ NP ++H D+K Sbjct: 126 HEIALGVNYL-HNMNPPLLHHDLK 148
>BMR1B_CHICK (Q05438) Bone morphogenetic protein receptor type IB precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6) (RPK-1) Length = 502 Score = 47.4 bits (111), Expect = 1e-05 Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGN----LLFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETE+ +RH N++ + G+ L DY ENGSL+D L K LD Sbjct: 244 ETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYL----KSTTLDTK 299 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 L++A + GL +LH P I HRD+K Sbjct: 300 GMLKLAYSSVSGLCHLHTGIFSTQGKPAIAHRDLK 334
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 46.6 bits (109), Expect = 2e-05 Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 2/90 (2%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGN--LLFYDYMENGSLWDLLHGPSKKVKLDWD 185 +F E + + +RHR +V L G P L+ +YM+NGSL + L P K K + + Sbjct: 259 KFVLEAKIMHKLRHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEYLKTPDGK-KTNLN 317 Query: 186 TRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + + ++G+AYL + ++VHRD++ Sbjct: 318 QMVHMMAEISEGMAYLESE---KVVHRDLR 344
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 45.8 bits (107), Expect = 3e-05 Identities = 27/83 (32%), Positives = 40/83 (48%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + +RH N++ G + +YM G+L LL P L W RL +A Sbjct: 95 EVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEP---LSWPVRLHLA 151 Query: 204 VGAAQGLAYLHHDCNPRIVHRDV 272 + AQGL YLH + HRD+ Sbjct: 152 LDIAQGLRYLH---AKGVFHRDL 171
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 45.8 bits (107), Expect = 3e-05 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 3/89 (3%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSK---KVKLDWD 185 F E++ + H+N+V G P + +YM GSL+++LH P+ KVK + Sbjct: 150 FIREVQNLKKGNHQNIVMFIGACYKPA--CIITEYMAGGSLYNILHNPNSSTPKVKYSFP 207 Query: 186 TRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L++A A GL +LH + IVHRD+ Sbjct: 208 LVLKMATDMALGLLHLH---SITIVHRDL 233
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 45.8 bits (107), Expect = 3e-05 Identities = 27/83 (32%), Positives = 40/83 (48%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + +RH N++ G + +YM G+L LL P L W RL +A Sbjct: 95 EVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEP---LSWPVRLHLA 151 Query: 204 VGAAQGLAYLHHDCNPRIVHRDV 272 + AQGL YLH + HRD+ Sbjct: 152 LDIAQGLRYLH---AKGVFHRDL 171
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 45.4 bits (106), Expect = 4e-05 Identities = 26/83 (31%), Positives = 41/83 (49%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + +RH N++ G + +YM G+L LL P L W RL +A Sbjct: 100 EVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEP---LSWPVRLHLA 156 Query: 204 VGAAQGLAYLHHDCNPRIVHRDV 272 + A+GL YLH + + HRD+ Sbjct: 157 LDIARGLRYLH---SKGVFHRDL 176
>ACVL1_RAT (P80203) Serine/threonine-protein kinase receptor R3 precursor (EC| 2.7.11.30) (SKR3) (TGF-B superfamily receptor type I) (TSR-I) Length = 504 Score = 45.1 bits (105), Expect = 5e-05 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETE+ +RH N++ ++ + L Y E+GSL+D L ++ L+ Sbjct: 243 ETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFL----QRQTLEPQ 298 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 LR+AV AA GLA+LH + P I HRD+K Sbjct: 299 LALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLK 333
>TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) Length = 617 Score = 45.1 bits (105), Expect = 5e-05 Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLS-PNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 F E+ + + H ++ G L+ P+ + Y+ GSL+ LLH +K LD ++ Sbjct: 505 FCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLH--EQKRILDLQSK 562 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L IAV A+G+ YLH+ P I+HRD+ Sbjct: 563 LIIAVDVARGMEYLHNLTQP-IIHRDL 588
>ACVL1_MOUSE (Q61288) Serine/threonine-protein kinase receptor R3 precursor (EC| 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I) Length = 502 Score = 45.1 bits (105), Expect = 5e-05 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETE+ +RH N++ ++ + L Y E+GSL+D L ++ L+ Sbjct: 241 ETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFL----QRQTLEPQ 296 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 LR+AV AA GLA+LH + P I HRD+K Sbjct: 297 LALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLK 331
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 45.1 bits (105), Expect = 5e-05 Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLS-PNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 F E+ + + H ++ G L+ P+ + Y+ GSL+ LLH +K LD ++ Sbjct: 607 FCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLH--EQKRILDLQSK 664 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L IAV A+G+ YLH+ P I+HRD+ Sbjct: 665 LIIAVDVAKGMEYLHNLTQP-IIHRDL 690
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 44.7 bits (104), Expect = 6e-05 Identities = 26/91 (28%), Positives = 52/91 (57%), Gaps = 2/91 (2%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH--GPSKKVKLDW 182 R+ + E++ + +++H N+V+ G L N +F +++ GS+ +++ GP ++ Sbjct: 1106 RKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRFGPLPEMVFCK 1165 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 T+ + QG+AYLH +C +VHRD+K Sbjct: 1166 YTKQIL-----QGVAYLHENC---VVHRDIK 1188
>RIPK2_HUMAN (O43353) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containi Length = 540 Score = 44.7 bits (104), Expect = 6e-05 Identities = 27/84 (32%), Positives = 42/84 (50%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E E + R ++ + G P + +YM NGSL +LLH ++ + W R RI Sbjct: 66 EAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRIL 125 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 A G+ YL H+ P ++H D+K Sbjct: 126 HEIALGVNYL-HNMTPPLLHHDLK 148
>LIMK1_DROME (Q8IR79) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (dLIMK)| Length = 1257 Score = 44.3 bits (103), Expect = 8e-05 Identities = 26/88 (29%), Positives = 46/88 (52%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R F E+ + + HR+++ G + +Y+ G L +L+H P++ L W Sbjct: 441 RNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQV--LPWPQ 498 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 R+R+A A G++YLH + I+HRD+ Sbjct: 499 RVRLARDIACGMSYLH---SMNIIHRDL 523
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 44.3 bits (103), Expect = 8e-05 Identities = 27/87 (31%), Positives = 45/87 (51%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 +F E E + + H LV L+G L L +++ME+G L D L S++ +T Sbjct: 407 DFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLR--SQRGLFAAETL 464 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L + + +G+AYL C ++HRD+ Sbjct: 465 LGMCLDVCEGMAYLEKAC---VIHRDL 488
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 44.3 bits (103), Expect = 8e-05 Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLS-PNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 F E+ + + H +V G L P+ + Y+ GSL+ LLH +K LD ++ Sbjct: 504 FCREVSILCQLNHPCVVQFVGACLDDPSQFAIVTQYISGGSLFSLLH--EQKRILDLQSK 561 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L IAV A+G+ YLH P I+HRD+ Sbjct: 562 LIIAVDVAKGMEYLHSLTQP-IIHRDL 587
>ACV1B_RAT (P80202) Activin receptor type 1B precursor (EC 2.7.11.30)| (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) Length = 505 Score = 44.3 bits (103), Expect = 8e-05 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ +RH N++ NG L DY E+GSL+D L+ + + + Sbjct: 247 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLN----RYTVTIE 302 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 +++A+ AA GLA+LH + P I HRD+K Sbjct: 303 GMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLK 337
>ACV1B_MOUSE (Q61271) Activin receptor type 1B precursor (EC 2.7.11.30)| (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) Length = 505 Score = 44.3 bits (103), Expect = 8e-05 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ +RH N++ NG L DY E+GSL+D L+ + + + Sbjct: 247 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLN----RYTVTIE 302 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 +++A+ AA GLA+LH + P I HRD+K Sbjct: 303 GMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLK 337
>ACV1B_HUMAN (P36896) Activin receptor type 1B precursor (EC 2.7.11.30)| (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) (Activin receptor-like kinase 4) (ALK-4) Length = 505 Score = 44.3 bits (103), Expect = 8e-05 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ +RH N++ NG L DY E+GSL+D L+ + + + Sbjct: 247 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLN----RYTVTIE 302 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 +++A+ AA GLA+LH + P I HRD+K Sbjct: 303 GMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLK 337
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 44.3 bits (103), Expect = 8e-05 Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLS-PNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 F E+ + + H +V G L P+ + Y+ GSL+ LLH +K LD ++ Sbjct: 505 FCREVSILCQLNHPCVVQFVGACLDDPSQFAIVTQYISGGSLFSLLH--EQKRILDLQSK 562 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L IAV A+G+ YLH P I+HRD+ Sbjct: 563 LIIAVDVAKGMEYLHSLTQP-IIHRDL 588
>ACVL1_HUMAN (P37023) Serine/threonine-protein kinase receptor R3 precursor (EC| 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I) Length = 503 Score = 43.9 bits (102), Expect = 1e-04 Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETE+ +RH N++ ++ + L Y E+GSL+D L ++ L+ Sbjct: 242 ETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFL----QRQTLEPH 297 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 LR+AV AA GLA+LH + P I HRD K Sbjct: 298 LALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDFK 332
>GUC2D_RAT (P51839) Olfactory guanylyl cyclase GC-D precursor (EC 4.6.1.2)| (Guanylate cyclase, olfactory) Length = 1110 Score = 43.9 bits (102), Expect = 1e-04 Identities = 21/71 (29%), Positives = 38/71 (53%) Frame = +3 Query: 27 LETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIAV 206 L + +RH N+ + G + P + + ++ GSL DLL ++ ++LDW + + + Sbjct: 601 LRKMREMRHENVTAFLGLFVGPEVSAMVLEHCARGSLEDLLR--NEDLRLDWTFKASLLL 658 Query: 207 GAAQGLAYLHH 239 +GL YLHH Sbjct: 659 DLIRGLRYLHH 669
>TRK1_LYMST (O76997) Putative neurotrophin receptor LTRK 1 precursor (EC| 2.7.10.1) Length = 794 Score = 43.5 bits (101), Expect = 1e-04 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 14/102 (13%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSL--WDLLHGPSKKVKLDW 182 R+FE E E + +I H N+V+ +G + ++ +++MENG L + +HGP D Sbjct: 550 RDFEREAEMLATIEHANIVTFYGVCTESDQWMMIFEFMENGDLNKYLRMHGPDAAFLKDR 609 Query: 183 DTR------------LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 D+ ++I + A + YL VHRD+ Sbjct: 610 DSMDSDEGQLTREQLMKIVLQIASAMEYL---ALQHFVHRDL 648
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 43.5 bits (101), Expect = 1e-04 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 2/91 (2%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLL--HGPSKKVKLDW 182 ++F E+E GS +H+NL L+GF L +Y+ G L+ L +GP + + Sbjct: 143 KQFRREVEIQGSFKHKNLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASY 202 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 A L Y+H + I+HRD+K Sbjct: 203 -----FVYQMANALDYMH---SKNILHRDIK 225
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 43.5 bits (101), Expect = 1e-04 Identities = 26/87 (29%), Positives = 45/87 (51%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 +F E E + + H LV L+G L L +++ME+G L D L +++ +T Sbjct: 402 DFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLR--TQRGLFAAETL 459 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L + + +G+AYL C ++HRD+ Sbjct: 460 LGMCLDVCEGMAYLEEAC---VIHRDL 483
>TGFR1_MOUSE (Q64729) TGF-beta receptor type-1 precursor (EC 2.7.11.30)| (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (ESK2) Length = 503 Score = 43.1 bits (100), Expect = 2e-04 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ +RH N++ NG L DY E+GSL+D L+ + V + Sbjct: 245 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTV----E 300 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 +++A+ A GLA+LH + P I HRD+K Sbjct: 301 GMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLK 335
>TGFR1_HUMAN (P36897) TGF-beta receptor type-1 precursor (EC 2.7.11.30)| (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5) Length = 503 Score = 43.1 bits (100), Expect = 2e-04 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ +RH N++ NG L DY E+GSL+D L+ + V + Sbjct: 245 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTV----E 300 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 +++A+ A GLA+LH + P I HRD+K Sbjct: 301 GMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLK 335
>TGFR1_RAT (P80204) TGF-beta receptor type-1 precursor (EC 2.7.11.30)| (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) Length = 501 Score = 43.1 bits (100), Expect = 2e-04 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ +RH N++ NG L DY E+GSL+D L+ + V + Sbjct: 243 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTV----E 298 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 +++A+ A GLA+LH + P I HRD+K Sbjct: 299 GMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLK 333
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 43.1 bits (100), Expect = 2e-04 Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 3/89 (3%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSK---KVKLDWDT 188 ET+++ + ++H N+++ G + +Y +G L+++L K ++ +DW T Sbjct: 202 ETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWST 261 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 G A G+ YLH +I+HRD+K Sbjct: 262 ------GIASGMNYLHLH---KIIHRDLK 281
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 43.1 bits (100), Expect = 2e-04 Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 3/89 (3%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSK---KVKLDWDT 188 ET+++ + ++H N+++ G + +Y +G L+++L K ++ +DW T Sbjct: 202 ETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWST 261 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 G A G+ YLH +I+HRD+K Sbjct: 262 ------GIASGMNYLHLH---KIIHRDLK 281
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 42.7 bits (99), Expect = 2e-04 Identities = 26/84 (30%), Positives = 45/84 (53%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E + +++H N+ +L G L+ L+ +Y GSL +L G K+ D + A Sbjct: 189 EAKLFWALKHENIAALRGVCLNTKLCLVM-EYARGGSLNRILAG-----KIPPDVLVNWA 242 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + A+G+ YLH++ I+HRD+K Sbjct: 243 IQIARGMNYLHNEAPMSIIHRDLK 266
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 42.4 bits (98), Expect = 3e-04 Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDW 182 A+ F E + +RH NLV L G + G L + +YM GSL D L + V L Sbjct: 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSV-LGG 288 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 D L+ ++ + + YL + VHRD+ Sbjct: 289 DCLLKFSLDVCEAMEYLEGN---NFVHRDL 315
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 42.4 bits (98), Expect = 3e-04 Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDW 182 A+ F E + +RH NLV L G + G L + +YM GSL D L + V L Sbjct: 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSV-LGG 288 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 D L+ ++ + + YL + VHRD+ Sbjct: 289 DCLLKFSLDVCEAMEYLEGN---NFVHRDL 315
>VAB1_CAEEL (O61460) Ephrin receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase Eph receptor) (Variable abnormal protein 1) Length = 1122 Score = 42.4 bits (98), Expect = 3e-04 Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 1/75 (1%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKK-VKLDWDT 188 EF TE +G H N++ L G S ++ +YM NGSL L ++ K+ W+ Sbjct: 761 EFLTEATIMGQFSHPNVIRLIGVVTSAEPVMIVAEYMANGSLDQFLRNTDQRGEKVHWEK 820 Query: 189 RLRIAVGAAQGLAYL 233 + G A G+ YL Sbjct: 821 ITEMLYGIASGMKYL 835
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 42.4 bits (98), Expect = 3e-04 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPN-----GNLLFYDYMENGSLWDLLHGPSKKV 170 +++ E++ + ++RH N++ L G + + G L +MENGSL LL + Sbjct: 55 SKKISREVKAMVNLRHENVLLLLGVTENLEWDYVYGPALVTGFMENGSLSGLLQPSCPR- 113 Query: 171 KLDWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W R+ G+ YLH NP ++HRD+K Sbjct: 114 --PWPLLCRLLEEVVLGMCYLH-SLNPSLLHRDLK 145
>ACVR1_HUMAN (Q04771) Activin receptor type-1 precursor (EC 2.7.11.30) (Activin| receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (Activin receptor-like kinase 2) (ALK-2) (TGF-B superfamily receptor type I) (TSR-I) Length = 509 Score = 42.4 bits (98), Expect = 3e-04 Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETEL +RH N++ ++ + L Y E GSL+D L + LD Sbjct: 248 ETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYL----QLTTLDTV 303 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 + LRI + A GLA+LH + P I HRD+K Sbjct: 304 SCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLK 338
>ACVR1_BOVIN (Q28041) Activin receptor type-1 precursor (EC 2.7.11.30) (Activin| receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) Length = 509 Score = 42.4 bits (98), Expect = 3e-04 Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETEL +RH N++ ++ + L Y E GSL+D L + LD Sbjct: 248 ETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYL----QLTTLDTV 303 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 + LRI + A GLA+LH + P I HRD+K Sbjct: 304 SCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLK 338
>ACVL1_PONPY (Q5RAN0) Serine/threonine-protein kinase receptor R3 precursor (EC| 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) Length = 503 Score = 42.4 bits (98), Expect = 3e-04 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETE+ +RH N++ ++ + L Y E+GSL+D L ++ L+ Sbjct: 242 ETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFL----QRQTLEPH 297 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 LR+ V AA GLA+LH + P I HRD K Sbjct: 298 LALRLTVSAACGLAHLHVEIFGTQGKPAIAHRDFK 332
>WIS4_SCHPO (O14299) MAP kinase kinase kinase wis4 (EC 2.7.11.25) (MAP kinase| kinase kinase wak1) (MAP kinase kinase kinase wik1) Length = 1401 Score = 42.0 bits (97), Expect = 4e-04 Identities = 26/90 (28%), Positives = 49/90 (54%), Gaps = 2/90 (2%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLL-HGPSKKVKLDWDT 188 + E+ + + H N+V+ +G + +F ++ + GSL DLL HG +++ + Sbjct: 1082 QIHNEMTVLERLNHPNVVTYYGVEVHREKVYIFMEFCQGGSLADLLAHG-----RIEDEN 1136 Query: 189 RLRI-AVGAAQGLAYLHHDCNPRIVHRDVK 275 L++ V +GLAY+H + I+HRD+K Sbjct: 1137 VLKVYVVQLLEGLAYIH---SQHILHRDIK 1163
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 42.0 bits (97), Expect = 4e-04 Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 1/90 (1%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDW 182 A+ F E + +RH NLV L G + G L + +YM GSL D L + V L Sbjct: 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSV-LGG 288 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 D L+ ++ + + YL + VHRD+ Sbjct: 289 DCLLKFSLDVLEAMEYLEGN---NFVHRDL 315
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 41.6 bits (96), Expect = 5e-04 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 2/91 (2%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDL--LHGPSKKVKLDW 182 ++F E+E S+ H NL +G+ L +Y+ NG ++ L LHGP + L Sbjct: 147 KQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDI-LAS 205 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 D +I A L Y+H I+HRD+K Sbjct: 206 DYIYQI----ANALDYMH---KKNIIHRDIK 229
>SSK2_YEAST (P53599) MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of| sensor kinase 2) Length = 1579 Score = 41.6 bits (96), Expect = 5e-04 Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 1/85 (1%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLL-HGPSKKVKLDWDTRLRI 200 E+ + + H N+VS +G + + +F +Y E GSL LL HG +++ + T++ Sbjct: 1315 EMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHG---RIEDEMVTQV-Y 1370 Query: 201 AVGAAQGLAYLHHDCNPRIVHRDVK 275 + +GLAYLH IVHRDVK Sbjct: 1371 TLQLLEGLAYLHES---GIVHRDVK 1392
>JAK1_MOUSE (P52332) Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1)| (JAK-1) Length = 1153 Score = 41.2 bits (95), Expect = 7e-04 Identities = 25/89 (28%), Positives = 48/89 (53%), Gaps = 2/89 (2%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGN--LLFYDYMENGSLWDLLHGPSKKVKLDWD 185 + + E+E + ++ H N+V G + GN L +++ +GSL + L P K K++ Sbjct: 920 DLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPSGSLKEYL--PKNKNKINLK 977 Query: 186 TRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 +L+ A+ +G+ YL + + VHRD+ Sbjct: 978 QQLKYAIQICKGMDYLG---SRQYVHRDL 1003
>GUC2F_HUMAN (P51841) Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2)| (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F) Length = 1108 Score = 41.2 bits (95), Expect = 7e-04 Identities = 22/70 (31%), Positives = 36/70 (51%) Frame = +3 Query: 30 ETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIAVG 209 E + +RH N+ L GF + ++ GSL D+L ++ VKLDW + + + Sbjct: 596 EMMKDLRHENINPLLGFFYDSGMFAIVTEFCSRGSLEDIL--TNQDVKLDWMFKSSLLLD 653 Query: 210 AAQGLAYLHH 239 +G+ YLHH Sbjct: 654 LIKGMKYLHH 663
>JAK2_RAT (Q62689) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHG--FSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDW 182 R+FE E+E + S++H N+V G +S L +Y+ GSL D L K ++D Sbjct: 893 RDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQ--KHKERIDH 950 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L+ +G+ YL R +HRD+ Sbjct: 951 KKLLQYTSQICKGMEYLG---TKRYIHRDL 977
>JAK2_MOUSE (Q62120) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1129 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHG--FSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDW 182 R+FE E+E + S++H N+V G +S L +Y+ GSL D L K ++D Sbjct: 893 RDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQ--KHKERIDH 950 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L+ +G+ YL R +HRD+ Sbjct: 951 KKLLQYTSQICKGMEYLG---TKRYIHRDL 977
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 40.8 bits (94), Expect = 0.001 Identities = 24/89 (26%), Positives = 47/89 (52%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 ++F++E+ + + H N+V P + +YM G+L L+ + L +T Sbjct: 130 QQFKSEVALLSRLFHPNIVQFIAACKKPPVYCIITEYMSQGNLRMYLN-KKEPYSLSIET 188 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 LR+A+ ++G+ YLH + ++HRD+K Sbjct: 189 VLRLALDISRGMEYLH---SQGVIHRDLK 214
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 40.8 bits (94), Expect = 0.001 Identities = 23/77 (29%), Positives = 40/77 (51%) Frame = +3 Query: 45 IRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIAVGAAQGL 224 +RH +V L G + L +YME G +L+H ++ + + RI V A +G+ Sbjct: 70 LRHSRVVKLLGIIIEEGNYSLVMEYMEKG---NLMHVLKTQIDVPLSLKGRIIVEAIEGM 126 Query: 225 AYLHHDCNPRIVHRDVK 275 YLH + ++H+D+K Sbjct: 127 CYLH---DKGVIHKDLK 140
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 40.8 bits (94), Expect = 0.001 Identities = 27/87 (31%), Positives = 46/87 (52%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + ++H LV L+ ++ + +YMENGSL D L PS +KL+ + L Sbjct: 284 FLAEANLMKQLQHPRLVRLYAV-VTQEPIYIITEYMENGSLVDFLKTPS-GIKLNVNKLL 341 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A+G+A++ +HRD++ Sbjct: 342 DMAAQIAEGMAFIEEQ---NYIHRDLR 365
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 40.8 bits (94), Expect = 0.001 Identities = 25/87 (28%), Positives = 41/87 (47%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 +F E + + + H LV L+G + + ++MENG L D L +K +L Sbjct: 310 DFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLR--ERKGQLQKALL 367 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L + +G+AYL C +HRD+ Sbjct: 368 LSMCQDICEGMAYLERSC---YIHRDL 391
>JAK1_HUMAN (P23458) Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1)| (JAK-1) Length = 1142 Score = 40.4 bits (93), Expect = 0.001 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 2/89 (2%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGN--LLFYDYMENGSLWDLLHGPSKKVKLDWD 185 + + E+E + ++ H N+V G GN L +++ +GSL + L P K K++ Sbjct: 909 DLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYL--PKNKNKINLK 966 Query: 186 TRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 +L+ AV +G+ YL + + VHRD+ Sbjct: 967 QQLKYAVQICKGMDYLG---SRQYVHRDL 992
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 40.4 bits (93), Expect = 0.001 Identities = 24/84 (28%), Positives = 41/84 (48%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E + ++H N+++L G L L ++ G L +L G ++ D + A Sbjct: 191 EAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGK----RIPPDILVNWA 246 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 V A+G+ YLH + I+HRD+K Sbjct: 247 VQIARGMNYLHDEAIVPIIHRDLK 270
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 40.4 bits (93), Expect = 0.001 Identities = 27/87 (31%), Positives = 46/87 (52%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + ++H+ LV L+ ++ + +YMENGSL D L PS +KL + L Sbjct: 284 FLAEANLMKQLQHQRLVRLYAV-VTQEPIYIITEYMENGSLVDFLKTPS-GIKLTINKLL 341 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A+G+A++ +HRD++ Sbjct: 342 DMAAQIAEGMAFIE---ERNYIHRDLR 365
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 40.4 bits (93), Expect = 0.001 Identities = 27/87 (31%), Positives = 46/87 (52%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + ++H+ LV L+ ++ + +YMENGSL D L PS +KL + L Sbjct: 284 FLAEANLMKQLQHQRLVRLYAV-VTQEPIYIITEYMENGSLVDFLKTPS-GIKLTINKLL 341 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A+G+A++ +HRD++ Sbjct: 342 DMAAQIAEGMAFIE---ERNYIHRDLR 365
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 40.4 bits (93), Expect = 0.001 Identities = 26/88 (29%), Positives = 42/88 (47%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 E E E+ + IRH N+++LH + +L + + G L+D L ++K L D Sbjct: 60 EIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFL---AEKESLTEDEA 116 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + G+ YLH + RI H D+K Sbjct: 117 TQFLKQILDGVHYLH---SKRIAHFDLK 141
>ACV1C_HUMAN (Q8NER5) Activin receptor type 1C precursor (EC 2.7.11.30)| (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7) Length = 493 Score = 40.0 bits (92), Expect = 0.002 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ +RH N++ NG L +Y E GSL+D L+ V Sbjct: 235 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVA---- 290 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 +++A+ A GLA+LH + P I HRD+K Sbjct: 291 GMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIK 325
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 40.0 bits (92), Expect = 0.002 Identities = 27/87 (31%), Positives = 45/87 (51%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + ++H+ LV L+ ++ + +YMENGSL D L PS +KL + L Sbjct: 284 FLAEANLMKQLQHKRLVRLYAV-VTEEPIYIITEYMENGSLVDFLKTPS-GIKLTINKLL 341 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A +G+A+L +HRD++ Sbjct: 342 DMAAQIVEGMAFLE---ERNYIHRDLR 365
>JAK2_HUMAN (O60674) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 40.0 bits (92), Expect = 0.002 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHG--FSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDW 182 R+FE E+E + S++H N+V G +S L +Y+ GSL D L K ++D Sbjct: 893 RDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQ--KHKERIDH 950 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L+ +G+ YL R +HRD+ Sbjct: 951 IKLLQYTSQICKGMEYLG---TKRYIHRDL 977
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 40.0 bits (92), Expect = 0.002 Identities = 27/89 (30%), Positives = 40/89 (44%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 ++F E+E S+RH NL L+G+ L +Y+ NG L+ L G S + Sbjct: 152 KQFRREVEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRS---HFNDVV 208 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 A L Y+H I+HRD+K Sbjct: 209 ASYYVYQMADALDYMH---ERNILHRDIK 234
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 40.0 bits (92), Expect = 0.002 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDW 182 A+ F E + +RH NLV L G + L + +YM GSL D L + V L Sbjct: 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGLYIVTEYMAKGSLVDYLRSRGRSV-LGG 288 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 D L+ ++ + + YL + VHRD+ Sbjct: 289 DCLLKFSLDVCEAMEYLEAN---NFVHRDL 315
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 40.0 bits (92), Expect = 0.002 Identities = 26/88 (29%), Positives = 42/88 (47%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 E E E+ + IRH N+++LH + +L + + G L+D L ++K L D Sbjct: 60 EIEREVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFL---AEKESLTEDEA 116 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + G+ YLH + RI H D+K Sbjct: 117 TQFLKQILDGVHYLH---SKRIAHFDLK 141
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 40.0 bits (92), Expect = 0.002 Identities = 26/88 (29%), Positives = 42/88 (47%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 E E E+ + IRH N+++LH + +L + + G L+D L ++K L D Sbjct: 60 EIEREVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFL---AEKESLTEDEA 116 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + G+ YLH + RI H D+K Sbjct: 117 TQFLKQILDGVHYLH---SKRIAHFDLK 141
>ACV1C_RAT (P70539) Activin receptor type 1C precursor (EC 2.7.11.30)| (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7) Length = 493 Score = 39.7 bits (91), Expect = 0.002 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ +RH N++ NG L +Y E GSL+D L+ V Sbjct: 235 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVA---- 290 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 +++A+ A GLA+LH + P I HRD+K Sbjct: 291 GMVKLALSIASGLAHLHMEIVGTQGKPAIAHRDIK 325
>ACV1C_MOUSE (Q8K348) Activin receptor type 1C precursor (EC 2.7.11.30)| (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7) Length = 493 Score = 39.7 bits (91), Expect = 0.002 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ +RH N++ NG L +Y E GSL+D L+ V Sbjct: 235 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVA---- 290 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 +++A+ A GLA+LH + P I HRD+K Sbjct: 291 GMVKLALSIASGLAHLHMEIVGTQGKPAIAHRDIK 325
>SSK22_YEAST (P25390) Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP| kinase kinase kinase SSK22) (Suppressor of sensor kinase 22) Length = 1331 Score = 39.3 bits (90), Expect = 0.003 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLL-HGPSKKVKLDWDTRLRI 200 E+ + + H N+V +G + + +F +Y E GSL LL HG +++ + T++ Sbjct: 1083 EMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHG---RIEDEMVTQV-Y 1138 Query: 201 AVGAAQGLAYLHHDCNPRIVHRDVK 275 +GLAYLH +VHRD+K Sbjct: 1139 TFELLEGLAYLHQS---GVVHRDIK 1160
>ACVR1_RAT (P80201) Activin receptor type-1 precursor (EC 2.7.11.30) (Activin| receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) Length = 509 Score = 39.3 bits (90), Expect = 0.003 Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETEL +RH N++ ++ + L Y E GSL+D L + LD Sbjct: 248 ETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYL----QLTTLDTV 303 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 + LRI + A GLA+LH + I HRD+K Sbjct: 304 SCLRIVLSIASGLAHLHIEIFGTQGKSAIAHRDLK 338
>ACVR1_MOUSE (P37172) Activin receptor type-1 precursor (EC 2.7.11.30) (Activin| receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) (TSK-7L) Length = 509 Score = 39.3 bits (90), Expect = 0.003 Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 9/95 (9%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL----LFYDYMENGSLWDLLHGPSKKVKLDWD 185 ETEL +RH N++ ++ + L Y E GSL+D L + LD Sbjct: 248 ETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYL----QLTTLDTV 303 Query: 186 TRLRIAVGAAQGLAYLHHDC-----NPRIVHRDVK 275 + LRI + A GLA+LH + I HRD+K Sbjct: 304 SCLRIVLSIASGLAHLHIEIFGTQGKSAIAHRDLK 338
>SRK1_SCHPO (O94547) Serine/threonine-protein kinase srk1 (EC 2.7.11.1)| (Sty1-regulated kinase 1) Length = 580 Score = 39.3 bits (90), Expect = 0.003 Identities = 22/84 (26%), Positives = 38/84 (45%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + ++H N++ L F +P L + + G +L H + D + Sbjct: 181 EVQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGG---ELFHQIVRLTYFSEDLSRHVI 237 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 A + YLH DC +VHRD+K Sbjct: 238 TQVAHAIRYLHEDCG--VVHRDIK 259
>ACK1_HUMAN (Q07912) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine| kinase non-receptor protein 2) Length = 1036 Score = 38.9 bits (89), Expect = 0.003 Identities = 29/87 (33%), Positives = 44/87 (50%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 +F E+ + S+ HRNL+ L+G L+P ++ + GSL D L L T Sbjct: 173 DFIREVNAMHSLDHRNLIRLYGVVLTPPMKMV-TELAPLGSLLDRLRKHQGHFLL--GTL 229 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 R AV A+G+ YL + R +HRD+ Sbjct: 230 SRYAVQVAEGMGYLE---SKRFIHRDL 253
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 38.9 bits (89), Expect = 0.003 Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLS--PNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 F+ E+ + +RH N+V G + + + + ++M GSL L ++ + Sbjct: 1332 FQNEVGILSKLRHPNVVQFLGACTAGGEDHHCIVTEWMGGGSLRQFLTDHFNLLEQNPHI 1391 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 RL++A+ A+G+ YL H P I+HRD+ Sbjct: 1392 RLKLALDIAKGMNYL-HGWTPPILHRDL 1418
>AVR2A_SHEEP (Q28560) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 38.9 bits (89), Expect = 0.003 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFS---LSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ ++ ++H N++ G S + +L L + E GSL D L K + W+ Sbjct: 232 EYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFL----KANVVSWN 287 Query: 186 TRLRIAVGAAQGLAYLHHDC-------NPRIVHRDVK 275 IA A+GLAYLH D P I HRD+K Sbjct: 288 ELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIK 324
>AVR2A_RAT (P38444) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 38.9 bits (89), Expect = 0.003 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFS---LSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ ++ ++H N++ G S + +L L + E GSL D L K + W+ Sbjct: 232 EYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFL----KANVVSWN 287 Query: 186 TRLRIAVGAAQGLAYLHHDC-------NPRIVHRDVK 275 IA A+GLAYLH D P I HRD+K Sbjct: 288 ELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIK 324
>AVR2A_MOUSE (P27038) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 38.9 bits (89), Expect = 0.003 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFS---LSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ ++ ++H N++ G S + +L L + E GSL D L K + W+ Sbjct: 232 EYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFL----KANVVSWN 287 Query: 186 TRLRIAVGAAQGLAYLHHDC-------NPRIVHRDVK 275 IA A+GLAYLH D P I HRD+K Sbjct: 288 ELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIK 324
>AVR2A_HUMAN (P27037) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) (ACTRIIA) Length = 513 Score = 38.9 bits (89), Expect = 0.003 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFS---LSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ ++ ++H N++ G S + +L L + E GSL D L K + W+ Sbjct: 232 EYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFL----KANVVSWN 287 Query: 186 TRLRIAVGAAQGLAYLHHDC-------NPRIVHRDVK 275 IA A+GLAYLH D P I HRD+K Sbjct: 288 ELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIK 324
>AVR2A_BOVIN (Q28043) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 38.9 bits (89), Expect = 0.003 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFS---LSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDWD 185 E E+ ++ ++H N++ G S + +L L + E GSL D L K + W+ Sbjct: 232 EYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFL----KANVVSWN 287 Query: 186 TRLRIAVGAAQGLAYLHHDC-------NPRIVHRDVK 275 IA A+GLAYLH D P I HRD+K Sbjct: 288 ELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIK 324
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 38.9 bits (89), Expect = 0.003 Identities = 29/88 (32%), Positives = 42/88 (47%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 E E + + + R ++ ++G P G L +YME GSL LL L WD R Sbjct: 65 ELLEEAKKMEMAKFRYILPVYGICREPVG--LVMEYMETGSLEKLLASEP----LPWDLR 118 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 RI A G+ +L H P ++H D+K Sbjct: 119 FRIIHETAVGMNFL-HCMAPPLLHLDLK 145
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 38.9 bits (89), Expect = 0.003 Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 4/88 (4%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG----PSKKVKLDWDTR 191 E++ + S+RH N+++ H + + + M +G+L + + P+ K+ W + Sbjct: 62 EIDILKSVRHPNIITFHDAWYNETEFVFITELMTSGTLREYIRKLTPLPNIKIVKRWCRQ 121 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + +GLAYLH P I+HRD+K Sbjct: 122 I------LKGLAYLHGH-EPPIIHRDIK 142
>M4K5_MOUSE (Q8BPM2) Mitogen-activated protein kinase kinase kinase kinase 5| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) Length = 847 Score = 38.5 bits (88), Expect = 0.005 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH--GPSKKVKLDWDTR 191 + E+ V +H N+V+ G LS + +Y GSL D+ H GP ++++ + R Sbjct: 63 QQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSEMQIAYVCR 122 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + QGLAYLH +HRD+K Sbjct: 123 ETL-----QGLAYLH---TKGKMHRDIK 142
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 38.5 bits (88), Expect = 0.005 Identities = 26/85 (30%), Positives = 41/85 (48%) Frame = +3 Query: 21 TELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRI 200 +E+ T+ + H N+V GF N LF +Y+ GS+ L+ + D + Sbjct: 1227 SEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIR---MYGRFDEPLIKHL 1283 Query: 201 AVGAAQGLAYLHHDCNPRIVHRDVK 275 +GLAYLH + I+HRD+K Sbjct: 1284 TTQVLKGLAYLH---SKGILHRDMK 1305
>M4K5_HUMAN (Q9Y4K4) Mitogen-activated protein kinase kinase kinase kinase 5| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5) (Kinase homologous to SPS1/STE20) (KHS) Length = 846 Score = 38.5 bits (88), Expect = 0.005 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH--GPSKKVKLDWDTR 191 + E+ V +H N+V+ G LS + +Y GSL D+ H GP ++++ + R Sbjct: 63 QQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCR 122 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + QGLAYLH +HRD+K Sbjct: 123 ETL-----QGLAYLH---TKGKMHRDIK 142
>AMHR2_RAT (Q62893) Anti-Muellerian hormone type-2 receptor precursor (EC| 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) (C14) Length = 557 Score = 38.1 bits (87), Expect = 0.006 Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 6/67 (8%) Frame = +3 Query: 90 PNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIAVGAAQGLAYLHHD------CNP 251 P+G LL + GSL L + DW + LR+A+ A+GLA+LH + P Sbjct: 270 PSGPLLVLELYPKGSLCHYL----TQYTSDWGSSLRMALSLAEGLAFLHGERWQDGQYKP 325 Query: 252 RIVHRDV 272 I HRD+ Sbjct: 326 GIAHRDL 332
>MYLK2_RABIT (P07313) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 607 Score = 38.1 bits (87), Expect = 0.006 Identities = 22/84 (26%), Positives = 45/84 (53%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E+E + + HRNL+ L+ +P+ +LF +Y+E G L++ + + + DT + + Sbjct: 341 EIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHL-TEVDTMVFVR 399 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 G+ ++H R++H D+K Sbjct: 400 -QICDGILFMH---KMRVLHLDLK 419
>MYLK2_HUMAN (Q9H1R3) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 595 Score = 38.1 bits (87), Expect = 0.006 Identities = 22/84 (26%), Positives = 45/84 (53%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E+E + + HRNL+ L+ +P+ +LF +Y+E G L++ + + + DT + + Sbjct: 329 EIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHL-TEVDTMVFVR 387 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 G+ ++H R++H D+K Sbjct: 388 -QICDGILFMH---KMRVLHLDLK 407
>TAOK2_XENLA (Q6GPK9) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1025 Score = 38.1 bits (87), Expect = 0.006 Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + +RH N + G L + L +Y GS DLL K ++ + IA Sbjct: 76 EVKFLQKLRHPNTIEYKGCYLREHTAWLVMEYCL-GSASDLLEVHKKPLQ-----EMEIA 129 Query: 204 V---GAAQGLAYLHHDCNPRIVHRDVK 275 GA QGLAYLH N ++HRDVK Sbjct: 130 AITHGALQGLAYLH---NHNMIHRDVK 153
>M3K8_RAT (Q63562) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (Tumor progression locus 2) (TPL-2) Length = 467 Score = 38.1 bits (87), Expect = 0.006 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 2/87 (2%) Frame = +3 Query: 21 TELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH--GPSKKVKLDWDTRL 194 +++E RH N+ L+G L + LF + E GS+ + L GP ++ ++ W T+ Sbjct: 177 SDVEIQACFRHENIAELYGAVLWGDTVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTK- 235 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +GL +LH + +++H D+K Sbjct: 236 ----HVLKGLDFLH---SKKVIHHDIK 255
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 37.7 bits (86), Expect = 0.008 Identities = 26/84 (30%), Positives = 41/84 (48%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + ++H N+V+L+ F N L +Y G L D LH L DT +R+ Sbjct: 63 EIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMR---TLSEDT-IRLF 118 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + G L H + I+HRD+K Sbjct: 119 LQQIAGAMRLLH--SKGIIHRDLK 140
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 37.7 bits (86), Expect = 0.008 Identities = 27/86 (31%), Positives = 40/86 (46%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLR 197 E E+ + I+H N+V+L SPN L + G L+D + + D T +R Sbjct: 67 ENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126 Query: 198 IAVGAAQGLAYLHHDCNPRIVHRDVK 275 + A + YLH IVHRD+K Sbjct: 127 QVLDA---VYYLH---RMGIVHRDLK 146
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 37.7 bits (86), Expect = 0.008 Identities = 27/86 (31%), Positives = 40/86 (46%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLR 197 E E+ + I+H N+V+L SPN L + G L+D + + D T +R Sbjct: 67 ENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126 Query: 198 IAVGAAQGLAYLHHDCNPRIVHRDVK 275 + A + YLH IVHRD+K Sbjct: 127 QVLDA---VYYLH---RMGIVHRDLK 146
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 37.7 bits (86), Expect = 0.008 Identities = 23/83 (27%), Positives = 40/83 (48%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + + H N++ G + +Y+ +G+L LL + L W R+++A Sbjct: 101 EVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLL---DSNLHLPWTVRVKLA 157 Query: 204 VGAAQGLAYLHHDCNPRIVHRDV 272 A GL+YLH I HRD+ Sbjct: 158 YDIAVGLSYLHF---KGIFHRDL 177
>RIPK5_XENLA (Q67E01) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 916 Score = 37.7 bits (86), Expect = 0.008 Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 8/84 (9%) Frame = +3 Query: 48 RHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGP--------SKKVKLDWDTRLRIA 203 +H LV LHG +++ Y Y S+ LL K L +TRL+IA Sbjct: 695 KHERLVDLHG-------SVIDYSYGGGSSIAVLLITERLHRDLYVGLKTGLSLETRLQIA 747 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + +G+ +LH N +VHRD+K Sbjct: 748 LDVVEGIRFLH---NQGVVHRDIK 768
>GUC2F_BOVIN (O02740) Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2)| (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F) Length = 1103 Score = 37.7 bits (86), Expect = 0.008 Identities = 21/70 (30%), Positives = 35/70 (50%) Frame = +3 Query: 30 ETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIAVG 209 E + +RH N+ L GF + ++ SL D+L ++ VKLDW + + + Sbjct: 596 EMMKDLRHENINPLVGFFYDSGVFAIVTEFCSRRSLEDILM--NQDVKLDWMFKSSLLLD 653 Query: 210 AAQGLAYLHH 239 +G+ YLHH Sbjct: 654 LIKGMKYLHH 663
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 37.7 bits (86), Expect = 0.008 Identities = 28/88 (31%), Positives = 42/88 (47%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 REF +E +G H N++ L G ++ ++MENGSL L K+ + Sbjct: 681 REFLSEASIMGQFEHPNVIHLEGVVTKSRPVMIVTEFMENGSLDSFLR--QKEGQFSVLQ 738 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 + + G A G+ YL D N VHRD+ Sbjct: 739 LVGMLRGIAAGMRYL-SDMN--YVHRDL 763
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 37.7 bits (86), Expect = 0.008 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLS-----PNGNLLFYDYMENGSLWDLLHGPSKKV 170 +++ E++ + ++R+ N++ L G + +G L +MENGSL LL + Sbjct: 55 SKKISWEVKAMVNLRNENVLLLLGVTEDLQWDFVSGQALVTRFMENGSLAGLLQPECPR- 113 Query: 171 KLDWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W R+ G+ YL H +P ++HRD+K Sbjct: 114 --PWPLLCRLLQEVVLGMCYL-HSLDPPLLHRDLK 145
>ACK2_BOVIN (O02742) Activated CDC42 kinase 2 (EC 2.7.10.2) (ACK-2)| Length = 747 Score = 37.7 bits (86), Expect = 0.008 Identities = 29/87 (33%), Positives = 43/87 (49%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 +F E+ + S+ HRNL+ L+G L+P ++ + GSL D L L T Sbjct: 173 DFIREVNAMHSLDHRNLIRLYGVVLTPPMKMV-TELAPLGSLLDRLRKHQGHFLL--GTL 229 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 R AV A+G+ YL R +HRD+ Sbjct: 230 SRYAVQVAEGMGYLE---AKRFIHRDL 253
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 37.7 bits (86), Expect = 0.008 Identities = 23/83 (27%), Positives = 40/83 (48%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + + H N++ G + +Y+ +G+L LL + L W R+++A Sbjct: 101 EMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLL---DSNLYLPWTVRVKLA 157 Query: 204 VGAAQGLAYLHHDCNPRIVHRDV 272 A GL+YLH I HRD+ Sbjct: 158 YDIAVGLSYLHF---KGIFHRDL 177
>FLR4_CAEEL (Q9NLA1) Serine/threonine-protein kinase flr-4 (EC 2.7.11.1)| (Fluoride resistant protein 4) Length = 570 Score = 37.7 bits (86), Expect = 0.008 Identities = 22/75 (29%), Positives = 38/75 (50%) Frame = +3 Query: 51 HRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIAVGAAQGLAY 230 + +V+ G N + +Y+ GS+ DLL K L DT ++ + + L Y Sbjct: 105 NNRIVNFLGIYADSNQMYIMSEYLPRGSVKDLL----VKETLGEDTAIKYLMETVEALDY 160 Query: 231 LHHDCNPRIVHRDVK 275 LH+ +P ++HRD+K Sbjct: 161 LHN-LSPPVIHRDIK 174
>M3K8_MOUSE (Q07174) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 37.7 bits (86), Expect = 0.008 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 2/87 (2%) Frame = +3 Query: 21 TELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH--GPSKKVKLDWDTRL 194 +++E RH N+ L+G L + LF + E GS+ + L GP ++ ++ W T+ Sbjct: 177 SDVEIQACFRHENIAELYGAVLWGDTVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTK- 235 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +GL +LH + +++H D+K Sbjct: 236 ----HILKGLDFLH---SKKVIHHDIK 255
>M3K8_HUMAN (P41279) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 37.7 bits (86), Expect = 0.008 Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 2/87 (2%) Frame = +3 Query: 21 TELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH--GPSKKVKLDWDTRL 194 +++E RH N+ L+G L LF + E GS+ + L GP ++ ++ W T+ Sbjct: 177 SDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTK- 235 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +GL +LH + +++H D+K Sbjct: 236 ----HVLKGLDFLH---SKKVIHHDIK 255
>TOPK_MOUSE (Q9JJ78) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) Length = 330 Score = 37.4 bits (85), Expect = 0.010 Identities = 25/87 (28%), Positives = 47/87 (54%), Gaps = 3/87 (3%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDWDTR--L 194 E + + ++ H N++ F+ + +G+L L +Y SL DL+ +K + L Sbjct: 84 EAKILKNLNHPNIIGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVIL 143 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 R+A+ A+GL YLH + +++H D+K Sbjct: 144 RVALHMARGLKYLHQE--KKLLHGDIK 168
>RIPK5_XENTR (Q67E00) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 918 Score = 37.4 bits (85), Expect = 0.010 Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 8/84 (9%) Frame = +3 Query: 48 RHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGP--------SKKVKLDWDTRLRIA 203 +H LV LHG +++ Y Y S+ LL K L +TRL+IA Sbjct: 697 KHERLVDLHG-------SVIDYSYGGGSSIAVLLITERLHRDLYVGLKTGLSLETRLQIA 749 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + +G+ +LH N +VHRD+K Sbjct: 750 LDVVEGIRFLH---NQGLVHRDIK 770
>ANPRB_RAT (P16067) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 37.4 bits (85), Expect = 0.010 Identities = 21/77 (27%), Positives = 37/77 (48%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R+ EL+ + ++ +L G + P + +Y GSL D+L S + LDW Sbjct: 562 RQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDS--INLDWMF 619 Query: 189 RLRIAVGAAQGLAYLHH 239 R + +G+A+LH+ Sbjct: 620 RYSLINDLVKGMAFLHN 636
>ANPRB_MOUSE (Q6VVW5) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 37.4 bits (85), Expect = 0.010 Identities = 21/77 (27%), Positives = 37/77 (48%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R+ EL+ + ++ +L G + P + +Y GSL D+L S + LDW Sbjct: 562 RQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDS--INLDWMF 619 Query: 189 RLRIAVGAAQGLAYLHH 239 R + +G+A+LH+ Sbjct: 620 RYSLINDLVKGMAFLHN 636
>ANPRB_HUMAN (P20594) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 37.4 bits (85), Expect = 0.010 Identities = 21/77 (27%), Positives = 37/77 (48%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R+ EL+ + ++ +L G + P + +Y GSL D+L S + LDW Sbjct: 562 RQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDS--INLDWMF 619 Query: 189 RLRIAVGAAQGLAYLHH 239 R + +G+A+LH+ Sbjct: 620 RYSLINDLVKGMAFLHN 636
>ANPRB_BOVIN (P46197) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 37.4 bits (85), Expect = 0.010 Identities = 21/77 (27%), Positives = 37/77 (48%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R+ EL+ + ++ +L G + P + +Y GSL D+L S + LDW Sbjct: 562 RQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDS--INLDWMF 619 Query: 189 RLRIAVGAAQGLAYLHH 239 R + +G+A+LH+ Sbjct: 620 RYSLINDLVKGMAFLHN 636
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 37.4 bits (85), Expect = 0.010 Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 11/101 (10%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH----------- 152 A E +RH N++ L G L L ++ G+L L Sbjct: 165 AESVRREARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAAANAAPDPRAP 224 Query: 153 GPSKKVKLDWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 GP + ++ + AV A+G+ YLH + I+HRD+K Sbjct: 225 GPRRARRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLK 265
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 37.4 bits (85), Expect = 0.010 Identities = 23/83 (27%), Positives = 40/83 (48%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + + H N++ G + +Y+ +G+L LL + L W R+++A Sbjct: 101 EMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLL---DSDLYLPWTVRVKLA 157 Query: 204 VGAAQGLAYLHHDCNPRIVHRDV 272 A GL+YLH I HRD+ Sbjct: 158 YDIAVGLSYLHF---KGIFHRDL 177
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 37.0 bits (84), Expect = 0.013 Identities = 24/83 (28%), Positives = 38/83 (45%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++T+ +RH L+ LH + + M G+L L P + L L A Sbjct: 273 EIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRA-LRLPPLLGFA 331 Query: 204 VGAAQGLAYLHHDCNPRIVHRDV 272 A+G++YL R+VHRD+ Sbjct: 332 CQVAEGMSYLEEQ---RVVHRDL 351
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/87 (31%), Positives = 42/87 (48%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F+ E+ + RH N++ G+S P + + E SL+ LH + K + + Sbjct: 124 FKNEVGVLRKTRHVNILLFMGYSTKPQ-LAIVTQWCEGSSLYHHLH--IIETKFEMIKLI 180 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 IA AQG+ YLH I+HRD+K Sbjct: 181 DIARQTAQGMDYLH---AKSIIHRDLK 204
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/87 (31%), Positives = 42/87 (48%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F+ E+ + RH N++ G+S P + + E SL+ LH + K + + Sbjct: 60 FKNEVGVLRKTRHVNILLFMGYSTKPQ-LAIVTQWCEGSSLYHHLH--IIETKFEMIKLI 116 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 IA AQG+ YLH I+HRD+K Sbjct: 117 DIARQTAQGMDYLH---AKSIIHRDLK 140
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 37.0 bits (84), Expect = 0.013 Identities = 21/89 (23%), Positives = 45/89 (50%), Gaps = 3/89 (3%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG---PSKKVKLDWDT 188 ET+++ + ++H N+++ G + ++ G L+++L + + +DW Sbjct: 192 ETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDW-- 249 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 ++G A G+ YLH +I+HRD+K Sbjct: 250 ----SMGIAGGMNYLHLH---KIIHRDLK 271
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 37.0 bits (84), Expect = 0.013 Identities = 21/89 (23%), Positives = 45/89 (50%), Gaps = 3/89 (3%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG---PSKKVKLDWDT 188 ET+++ + ++H N+++ G + ++ G L+++L + + +DW Sbjct: 192 ETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDW-- 249 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 ++G A G+ YLH +I+HRD+K Sbjct: 250 ----SMGIAGGMNYLHLH---KIIHRDLK 271
>SPEG_RAT (Q63638) Striated muscle-specific serine/threonine protein kinase (EC| 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1) Length = 3259 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/91 (29%), Positives = 41/91 (45%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDW 182 G R E E + ++ H L+SLH ++P +L + N +LL G S + + Sbjct: 2995 GKRRVLQEYEVLRTLHHERLMSLHEAYITPRYLVLIAESCGNR---ELLCGLSDRFRYSE 3051 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 D V QGL YLH ++H D+K Sbjct: 3052 DDVATYVVQLLQGLDYLH---GRHVLHLDIK 3079
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/87 (31%), Positives = 42/87 (48%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F+ E+ + RH N++ G+S P + + E SL+ LH + K + + Sbjct: 108 FKNEVGVLRKTRHVNILLFMGYSTKPQ-LAIVTQWCEGSSLYHHLH--IIETKFEMIKLI 164 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 IA AQG+ YLH I+HRD+K Sbjct: 165 DIARQTAQGMDYLH---AKSIIHRDLK 188
>RIPK5_CHICK (Q6XUX0) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 930 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 8/83 (9%) Frame = +3 Query: 51 HRNLVSLHGFSLSPNGNLLFYDYMENGSL-----WDLLHGP---SKKVKLDWDTRLRIAV 206 H LV LHG +++ Y Y S+ + LH K L+ +TRL+IA+ Sbjct: 708 HERLVDLHG-------SVIDYGYGGGSSIAVLLIMERLHRDLYTGLKAGLELETRLQIAL 760 Query: 207 GAAQGLAYLHHDCNPRIVHRDVK 275 +G+ YLH + +VHRD+K Sbjct: 761 DVVEGIRYLH---SQGLVHRDIK 780
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/87 (31%), Positives = 42/87 (48%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F+ E+ + RH N++ G+S P + + E SL+ LH + K + + Sbjct: 498 FKNEVGVLRKTRHVNILLFMGYSTKPQ-LAIVTQWCEGSSLYHHLH--IIETKFEMIKLI 554 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 IA AQG+ YLH I+HRD+K Sbjct: 555 DIARQTAQGMDYLH---AKSIIHRDLK 578
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/87 (31%), Positives = 42/87 (48%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F+ E+ + RH N++ G+S P + + E SL+ LH + K + + Sbjct: 538 FKNEVGVLRKTRHVNILLFMGYSTKPQ-LAIVTQWCEGSSLYHHLH--IIETKFEMIKLI 594 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 IA AQG+ YLH I+HRD+K Sbjct: 595 DIARQTAQGMDYLH---AKSIIHRDLK 618
>LIMK1_RAT (P53669) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 37.0 bits (84), Expect = 0.013 Identities = 23/88 (26%), Positives = 41/88 (46%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R F E++ + + H N++ G +Y++ G+L ++ S + W Sbjct: 379 RTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIK--SMDSQYPWSQ 436 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 R+ A A G+AYLH + I+HRD+ Sbjct: 437 RVSFAKDIASGMAYLH---SMNIIHRDL 461
>LIMK1_HUMAN (P53667) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 37.0 bits (84), Expect = 0.013 Identities = 23/88 (26%), Positives = 41/88 (46%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R F E++ + + H N++ G +Y++ G+L ++ S + W Sbjct: 379 RTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIK--SMDSQYPWSQ 436 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 R+ A A G+AYLH + I+HRD+ Sbjct: 437 RVSFAKDIASGMAYLH---SMNIIHRDL 461
>AMHR2_HUMAN (Q16671) Anti-Muellerian hormone type-2 receptor precursor (EC| 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) Length = 573 Score = 37.0 bits (84), Expect = 0.013 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 6/66 (9%) Frame = +3 Query: 93 NGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIAVGAAQGLAYLHHD------CNPR 254 +G LL + GSL L + DW + LR+A+ AQGLA+LH + P Sbjct: 273 SGPLLVLELHPKGSLCHYL----TQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKPG 328 Query: 255 IVHRDV 272 I HRD+ Sbjct: 329 IAHRDL 334
>TAOK3_CHICK (Q9I9E0) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Kinase from chicken) Length = 898 Score = 37.0 bits (84), Expect = 0.013 Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH---GPSKKVKLDWDTRL 194 E++ + ++H N + G L + L +Y GS D+L P ++V++ Sbjct: 72 EVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCL-GSASDMLEVHKKPLQEVEI-----A 125 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 I GA QGLAYLH C +HRD+K Sbjct: 126 AITHGALQGLAYLHSHCK---IHRDIK 149
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 37.0 bits (84), Expect = 0.013 Identities = 24/84 (28%), Positives = 37/84 (44%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E+ + ++ H N+V HGF + +Y NGSL L+ S L + Sbjct: 70 EISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSS--TGLSENESKTYV 127 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 GL YLH + ++HRD+K Sbjct: 128 TQTLLGLKYLHGE---GVIHRDIK 148
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/87 (31%), Positives = 42/87 (48%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F+ E+ + RH N++ G+S P + + E SL+ LH + K + + Sbjct: 538 FKNEVGVLRKTRHVNILLFMGYSTKPQ-LAIVTQWCEGSSLYHHLH--IIETKFEMIKLI 594 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 IA AQG+ YLH I+HRD+K Sbjct: 595 DIARQTAQGMDYLH---AKSIIHRDLK 618
>SPEG_MOUSE (Q62407) Striated muscle-specific serine/threonine protein kinase (EC| 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1) Length = 3262 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/91 (29%), Positives = 41/91 (45%) Frame = +3 Query: 3 GAREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDW 182 G R E E + ++ H L+SLH ++P +L + N +LL G S + + Sbjct: 2998 GKRRVLQEYEVLRTLHHERLMSLHEAYITPRYLVLIAESCGNR---ELLCGLSDRFRYSE 3054 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 D V QGL YLH ++H D+K Sbjct: 3055 DDVATYVVQLLQGLDYLH---GHHVLHLDIK 3082
>GUC2G_MOUSE (Q6TL19) Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl| cyclase receptor G) (mGC-G) Length = 1100 Score = 37.0 bits (84), Expect = 0.013 Identities = 18/64 (28%), Positives = 29/64 (45%) Frame = +3 Query: 45 IRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIAVGAAQGL 224 ++H N+V G P + Y + GSL D++ ++ DW +L A GL Sbjct: 610 LKHENIVPFFGVCTEPPNICIVTQYCKKGSLQDVMRNSDHEI--DWIFKLSFAYDIVNGL 667 Query: 225 AYLH 236 +LH Sbjct: 668 LFLH 671
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 37.0 bits (84), Expect = 0.013 Identities = 22/84 (26%), Positives = 40/84 (47%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E + + +RH +V L G + L +YME G +L+H ++ + RI Sbjct: 63 EAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKG---NLMHVLKAEMSTPLSVKGRII 119 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + +G+ YLH ++H+D+K Sbjct: 120 LEIIEGMCYLH---GKGVIHKDLK 140
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 37.0 bits (84), Expect = 0.013 Identities = 21/89 (23%), Positives = 45/89 (50%), Gaps = 3/89 (3%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG---PSKKVKLDWDT 188 ET+++ + ++H N+++ G + ++ G L+++L + + +DW Sbjct: 159 ETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDW-- 216 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 ++G A G+ YLH +I+HRD+K Sbjct: 217 ----SMGIAGGMNYLHLH---KIIHRDLK 238
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 37.0 bits (84), Expect = 0.013 Identities = 22/87 (25%), Positives = 42/87 (48%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 +F E + + ++H NLV L+G + +YM++GSL + L K + + Sbjct: 565 DFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLL 624 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L + + ++G+ YL +HRD+ Sbjct: 625 LDMCIQVSKGMTYLERH---NYIHRDL 648
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 36.6 bits (83), Expect = 0.017 Identities = 23/88 (26%), Positives = 38/88 (43%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 + E+E ++H N++ L+ + L +Y G L+ L K KLD Sbjct: 87 QLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKEL---QKSEKLDEQRT 143 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 I A L Y H + +++HRD+K Sbjct: 144 ATIIEELADALTYCH---DKKVIHRDIK 168
>ACK1_MOUSE (O54967) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1)| (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2) Length = 1055 Score = 36.6 bits (83), Expect = 0.017 Identities = 29/87 (33%), Positives = 44/87 (50%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 +F E+ + S+ HRNL+ L+G L+ ++ + GSL D L L T Sbjct: 173 DFIREVNAMHSLDHRNLIRLYGVVLTLPMKMV-TELAPLGSLLDRLRKHQGHFLL--GTL 229 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 R AV A+G+AYL + R +HRD+ Sbjct: 230 SRYAVQVAEGMAYLE---SKRFIHRDL 253
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 36.6 bits (83), Expect = 0.017 Identities = 23/85 (27%), Positives = 45/85 (52%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLR 197 ++E++ + +RH+++++L+ + + + M GSL +LL +KV L L Sbjct: 233 QSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKV-LPVSELLD 291 Query: 198 IAVGAAQGLAYLHHDCNPRIVHRDV 272 IA A+G+ YL + +HRD+ Sbjct: 292 IAWQVAEGMCYLE---SQNYIHRDL 313
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 36.6 bits (83), Expect = 0.017 Identities = 27/87 (31%), Positives = 43/87 (49%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F+ E+ + RH N++ G P+ ++ + E SL+ +H K KL+ T + Sbjct: 470 FKNEVAMLKKTRHCNILLFMGCVSKPSLAIVT-QWCEGSSLYKHVHVSETKFKLN--TLI 526 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 I AQG+ YLH I+HRD+K Sbjct: 527 DIGRQVAQGMDYLH---AKNIIHRDLK 550
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 36.6 bits (83), Expect = 0.017 Identities = 24/88 (27%), Positives = 40/88 (45%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R F E++ + + H N++ G +Y++ G+L L+ S W Sbjct: 386 RTFLKEVKVMRCLEHPNVLKFIGVLYKEKRLNFITEYIKGGTLRGLIK--SMDSHYPWSQ 443 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 R+ A A G+AYLH + I+HRD+ Sbjct: 444 RVSFAKDIAAGMAYLH---SMNIIHRDL 468
>GUC2F_RAT (P51842) Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2)| (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F) Length = 1108 Score = 36.6 bits (83), Expect = 0.017 Identities = 21/70 (30%), Positives = 33/70 (47%) Frame = +3 Query: 30 ETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIAVG 209 E + +RH N+ L GF + ++ SL D+L VKLDW + + + Sbjct: 596 EMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDIL--TQDDVKLDWMFKSSLLLD 653 Query: 210 AAQGLAYLHH 239 +G+ YLHH Sbjct: 654 LIKGMKYLHH 663
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 36.6 bits (83), Expect = 0.017 Identities = 26/84 (30%), Positives = 41/84 (48%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + ++H N+V+L+ F N L +Y G L D LH L DT +R+ Sbjct: 63 EIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLH---TMRTLSEDT-VRLF 118 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + G L H + I+HRD+K Sbjct: 119 LQQIAGAMRLLH--SKGIIHRDLK 140
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 36.6 bits (83), Expect = 0.017 Identities = 27/87 (31%), Positives = 40/87 (45%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + + +RH LV L+ +S + +YM GSL D L G K L + Sbjct: 303 FLQEAQVMKKLRHEKLVQLYAM-VSEEPIYIVIEYMSKGSLLDFLKGEMGKY-LRLPQLV 360 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A G+AY+ VHRD++ Sbjct: 361 EMAAQIASGMAYVE---RMNYVHRDLR 384
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 36.6 bits (83), Expect = 0.017 Identities = 25/87 (28%), Positives = 39/87 (44%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 +F +E +G H N++ L G ++ +YMENG+L L K + Sbjct: 660 DFLSEASIMGQFSHHNIIPLEGVVSKYKPMMIITEYMENGALDKFLR--EKDGEFSVLQL 717 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDV 272 + + G A G+ YL N VHRD+ Sbjct: 718 VGMLRGIASGMKYL---ANMNYVHRDL 741
>AVR2B_XENLA (P27041) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 511 Score = 36.6 bits (83), Expect = 0.017 Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 13/99 (13%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL-----LFYDYMENGSLWDLLHGPSKKVKLDW 182 E E+ T ++H NL+ NL L + + GSL D L G + W Sbjct: 229 EKEIFTTPGMKHENLLEFIAAE-KRGSNLEMELWLITAFHDKGSLTDYLKGNL----VSW 283 Query: 183 DTRLRIAVGAAQGLAYLHHDC--------NPRIVHRDVK 275 + I A+GLAYLH D P I HRD K Sbjct: 284 NELCHITETMARGLAYLHEDVPRCKGEGHKPAIAHRDFK 322
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 36.6 bits (83), Expect = 0.017 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 5/95 (5%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGN-----LLFYDYMENGSLWDLLHGPSKKV 170 ++ E++ + S+ + ++ L G N + L +MENGSL LL + Sbjct: 54 SKAISREVKAMASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENGSLSGLLQSQCPR- 112 Query: 171 KLDWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 W R+ G+ YLH D NP ++HRD+K Sbjct: 113 --PWPLLCRLLKEVVLGMFYLH-DQNPVLLHRDLK 144
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 36.2 bits (82), Expect = 0.022 Identities = 23/88 (26%), Positives = 39/88 (44%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 + E+E +RH N++ L+G+ + L DY G L+ L K + D Sbjct: 184 QLRREVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFREL---QKCTRFDDQRS 240 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 A+ L Y H + +++HRD+K Sbjct: 241 AMYIKQLAEALLYCH---SKKVIHRDIK 265
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 36.2 bits (82), Expect = 0.022 Identities = 27/87 (31%), Positives = 41/87 (47%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + + +RH+ LV L+ +S + +YM GSL D L G K L + Sbjct: 306 FLQEAQVMKKLRHKKLVQLYAV-VSEEPIYIVIEYMSKGSLLDFLKGEMGKY-LRLPQLV 363 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A G+AY+ VHRD++ Sbjct: 364 DMAAQIASGMAYVE---RMNYVHRDLR 387
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 36.2 bits (82), Expect = 0.022 Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Frame = +3 Query: 45 IRHRNLVSLHGFSLSPNGNL-LFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIAVGAAQG 221 +RH+N+V G S S G L +F + + GSL LL +K + T QG Sbjct: 423 LRHKNIVRYLG-SASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQG 481 Query: 222 LAYLHHDCNPRIVHRDVK 275 L YLH + IVHRD+K Sbjct: 482 LGYLHDN---HIVHRDIK 496
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 36.2 bits (82), Expect = 0.022 Identities = 22/88 (25%), Positives = 40/88 (45%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R F E++ + + H N++ G +Y++ G+L ++ + W Sbjct: 379 RTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKNMDSQYP--WSQ 436 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 R+ A A G+AYLH + I+HRD+ Sbjct: 437 RVSFAKDIASGMAYLH---SMNIIHRDL 461
>GUC2D_HUMAN (Q02846) Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2)| (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC) Length = 1103 Score = 36.2 bits (82), Expect = 0.022 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 10/84 (11%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPN---------GNL-LFYDYMENGSLWDLLHGPSKK 167 +T + +RH N+ G L+ GNL + ++ GSL DLL ++ Sbjct: 578 KTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDLL--AQRE 635 Query: 168 VKLDWDTRLRIAVGAAQGLAYLHH 239 +KLDW + + + +G+ YLHH Sbjct: 636 IKLDWMFKSSLLLDLIKGIRYLHH 659
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 36.2 bits (82), Expect = 0.022 Identities = 24/83 (28%), Positives = 39/83 (46%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++T+ +RHRN+V + L + E GSL D + +K LD T + I Sbjct: 55 EIKTMKLLRHRNIVQFYETFFENGETYLVMELCEGGSLMDYV---KQKGPLDDSTAVHIL 111 Query: 204 VGAAQGLAYLHHDCNPRIVHRDV 272 + Y+H + I+HRD+ Sbjct: 112 RQLIAAVKYIHDE---NILHRDL 131
>SKM1_YEAST (Q12469) Serine/threonine-protein kinase SKM1 (EC 2.7.11.1)| (Protein kinase 75490 D) Length = 655 Score = 36.2 bits (82), Expect = 0.022 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 7/91 (7%) Frame = +3 Query: 24 ELETVGSIRHRNLVS-LHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLR- 197 EL + R N+V+ L + + + +YME G L D+L ++ + + L Sbjct: 422 ELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNE 481 Query: 198 -----IAVGAAQGLAYLHHDCNPRIVHRDVK 275 I QGL +LH N +I+HRD+K Sbjct: 482 NQMAYIVKETCQGLKFLH---NKKIIHRDIK 509
>AVR2B_RAT (P38445) Activin receptor type 2B precursor (EC 2.7.11.30) (Activin| receptor type IIB) (ACTR-IIB) Length = 513 Score = 36.2 bits (82), Expect = 0.022 Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 13/99 (13%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNL-----LFYDYMENGSLWDLLHGPSKKVKLDW 182 E E+ + ++H NL+ NL L + + GSL D L G + W Sbjct: 230 EREIFSTPGMKHENLLQFIAAEKRGCSNLEVELWLITAFHDKGSLTDYLKGNI----ITW 285 Query: 183 DTRLRIAVGAAQGLAYLHHDC--------NPRIVHRDVK 275 + +A ++GL+YLH D P I HRD K Sbjct: 286 NELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFK 324
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 36.2 bits (82), Expect = 0.022 Identities = 25/86 (29%), Positives = 41/86 (47%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLR 197 E E+ + S++H +++ L +P L + E+G L ++L +K + Sbjct: 161 EREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEIL---DRKGHFSENETRW 217 Query: 198 IAVGAAQGLAYLHHDCNPRIVHRDVK 275 I A +AYLH N IVHRD+K Sbjct: 218 IIQSLASAIAYLH---NNDIVHRDLK 240
>MYLK2_RAT (P20689) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 609 Score = 36.2 bits (82), Expect = 0.022 Identities = 21/84 (25%), Positives = 45/84 (53%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E+E + + HRNL+ L+ + + +LF +Y+E G L++ + ++ + DT + + Sbjct: 343 EIEVMNQLNHRNLIQLYSAIETSHEIILFMEYIEGGELFERIVDEDYQL-TEVDTMVFVR 401 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 G+ ++H R++H D+K Sbjct: 402 -QICDGILFMH---KMRVLHLDLK 421
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 36.2 bits (82), Expect = 0.022 Identities = 25/86 (29%), Positives = 39/86 (45%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + +RH++LV L+ + +YM GSL D L + V L T + Sbjct: 280 FLDEAGVMKKLRHKHLVQLYAICSDREPIYIVTEYMSGGSLLDYL-SKGEGVNLQLPTLI 338 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDV 272 +A A G+A+L +HRD+ Sbjct: 339 DMAAQVASGMAFLEAQ---GYIHRDL 361
>RIPK5_RAT (Q6XUX2) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 927 Score = 36.2 bits (82), Expect = 0.022 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 8/84 (9%) Frame = +3 Query: 48 RHRNLVSLHGFSLSPNGNLLFYDYMENGS-----LWDLLHGP---SKKVKLDWDTRLRIA 203 +H LV LHG +++ Y+Y S + + LH K L +TRL+IA Sbjct: 704 KHERLVDLHG-------SVIDYNYGGGSSVAVLLIMERLHRDLYTGLKAGLSLETRLQIA 756 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + +G+ +LH + +VHRD+K Sbjct: 757 LDVVEGIRFLH---SQGLVHRDIK 777
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 36.2 bits (82), Expect = 0.022 Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 2/86 (2%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLL--HGPSKKVKLDWDTRLR 197 E+ + + H N+V GF + +F +Y+ GS+ L +GP ++ + + +R Sbjct: 880 EISMIADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSR-- 937 Query: 198 IAVGAAQGLAYLHHDCNPRIVHRDVK 275 GL+YLH + I+HRD+K Sbjct: 938 ---QVLYGLSYLH---SKGIIHRDLK 957
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 36.2 bits (82), Expect = 0.022 Identities = 26/83 (31%), Positives = 39/83 (46%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E+E + S+RH L+ LH + + M G+L L G S+ L L A Sbjct: 277 EIEALKSLRHERLIRLHAICSLGEPVYIVTELMGKGNLQVYL-GSSEGKALSLPHLLGFA 335 Query: 204 VGAAQGLAYLHHDCNPRIVHRDV 272 A+G++YL R+VHRD+ Sbjct: 336 CQVAEGMSYLE---ERRVVHRDL 355
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 36.2 bits (82), Expect = 0.022 Identities = 24/86 (27%), Positives = 39/86 (45%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + RH LV+L+ + +YM GSL D L + L ++ + Sbjct: 324 FLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRY-LHFEDLI 382 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDV 272 IA A G+ YL + +++HRD+ Sbjct: 383 YIATQVASGMEYLE---SKQLIHRDL 405
>GUC2D_CANFA (O19179) Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2)| (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC) (Guanylate cyclase E) (GC-E) Length = 1109 Score = 36.2 bits (82), Expect = 0.022 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 10/84 (11%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGN----------LLFYDYMENGSLWDLLHGPSKK 167 +T + +RH N+V G L G + ++ GSL DLL + Sbjct: 582 KTAFSKLRELRHENVVLYLGLFLGSGGAGGSAAGEGVLAVVSEHCARGSLHDLL--AQRD 639 Query: 168 VKLDWDTRLRIAVGAAQGLAYLHH 239 +KLDW + + + +G+ YLHH Sbjct: 640 IKLDWMFKSSLLLDLIKGMRYLHH 663
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 35.8 bits (81), Expect = 0.029 Identities = 23/88 (26%), Positives = 39/88 (44%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 + E+E +RH N++ L+G+ L +Y G+++ L K K D Sbjct: 168 QLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL---QKLSKFDEQRT 224 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 A L+Y H + R++HRD+K Sbjct: 225 ATYITELANALSYCH---SKRVIHRDIK 249
>GCY3E_DROME (Q07553) Guanylate cyclase 32E precursor (EC 4.6.1.2)| Length = 1163 Score = 35.8 bits (81), Expect = 0.029 Identities = 21/76 (27%), Positives = 36/76 (47%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R EL+ + +RH N+++ G S ++F Y GSL D+L ++ + LD Sbjct: 570 RSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVL--ANEDLHLDHMF 627 Query: 189 RLRIAVGAAQGLAYLH 236 + +G+ YLH Sbjct: 628 ISSLVSDILKGMIYLH 643
>TAOK2_MOUSE (Q6ZQ29) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1055 Score = 35.8 bits (81), Expect = 0.029 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E+ + +RH N + G L + L +Y GS DLL K ++ + IA Sbjct: 76 EVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCL-GSASDLLEVHKKPLQ-----EVEIA 129 Query: 204 V---GAAQGLAYLHHDCNPRIVHRDVK 275 GA QGLAYLH + ++HRDVK Sbjct: 130 AVTHGALQGLAYLH---SHNMIHRDVK 153
>RIPK5_PANTR (Q4VSN5) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 930 Score = 35.8 bits (81), Expect = 0.029 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 8/84 (9%) Frame = +3 Query: 48 RHRNLVSLHGFSLSPNGNLLFYDYMENGSL-----WDLLHGP---SKKVKLDWDTRLRIA 203 +H LV LHG +++ Y+Y S+ + LH K L +TRL+IA Sbjct: 707 KHERLVDLHG-------SVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIA 759 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + +G+ +LH + +VHRD+K Sbjct: 760 LDVVEGIRFLH---SQGLVHRDIK 780
>TAOK2_RAT (Q9JLS3) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1235 Score = 35.8 bits (81), Expect = 0.029 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E+ + +RH N + G L + L +Y GS DLL K ++ + IA Sbjct: 76 EVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCL-GSASDLLEVHKKPLQ-----EVEIA 129 Query: 204 V---GAAQGLAYLHHDCNPRIVHRDVK 275 GA QGLAYLH + ++HRDVK Sbjct: 130 AVTHGALQGLAYLH---SHNMIHRDVK 153
>TAOK2_HUMAN (Q9UL54) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C) Length = 1235 Score = 35.8 bits (81), Expect = 0.029 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E+ + +RH N + G L + L +Y GS DLL K ++ + IA Sbjct: 76 EVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCL-GSASDLLEVHKKPLQ-----EVEIA 129 Query: 204 V---GAAQGLAYLHHDCNPRIVHRDVK 275 GA QGLAYLH + ++HRDVK Sbjct: 130 AVTHGALQGLAYLH---SHNMIHRDVK 153
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 35.8 bits (81), Expect = 0.029 Identities = 23/88 (26%), Positives = 39/88 (44%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 + E+E +RH N++ L+G+ L +Y G+++ L K K D Sbjct: 177 QLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL---QKLSKFDEQRT 233 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 A L+Y H + R++HRD+K Sbjct: 234 ATYITELANALSYCH---SKRVIHRDIK 258
>LRRK2_MOUSE (Q5S006) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 2527 Score = 35.8 bits (81), Expect = 0.029 Identities = 29/89 (32%), Positives = 42/89 (47%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R EL + + H +L+SL + P +L + GSL LL K L Sbjct: 1915 RLLRQELVVLCHLHHPSLISLLAAGIRPR--MLVMELASKGSLDRLLQ--QDKASLTRTL 1970 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + RIA+ A GL YLH + I++RD+K Sbjct: 1971 QHRIALHVADGLRYLH---SAMIIYRDLK 1996
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 35.8 bits (81), Expect = 0.029 Identities = 29/89 (32%), Positives = 42/89 (47%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R EL + + H +L+SL + P +L + GSL LL K L Sbjct: 1915 RLLRQELVVLCHLHHPSLISLLAAGIRPR--MLVMELASKGSLDRLLQ--QDKASLTRTL 1970 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 + RIA+ A GL YLH + I++RD+K Sbjct: 1971 QHRIALHVADGLRYLH---SAMIIYRDLK 1996
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 35.8 bits (81), Expect = 0.029 Identities = 27/87 (31%), Positives = 41/87 (47%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + + +RH LV L+ +S + +YM GSL D L G + K L + Sbjct: 309 FLQEAQVMKKLRHEKLVQLYAV-VSEEPIYIVTEYMSKGSLLDFLKGETGKY-LRLPQLV 366 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A G+AY+ VHRD++ Sbjct: 367 DMAAQIASGMAYVE---RMNYVHRDLR 390
>RIPK5_HUMAN (Q6XUX3) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) Length = 929 Score = 35.8 bits (81), Expect = 0.029 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 8/84 (9%) Frame = +3 Query: 48 RHRNLVSLHGFSLSPNGNLLFYDYMENGSL-----WDLLHGP---SKKVKLDWDTRLRIA 203 +H LV LHG +++ Y+Y S+ + LH K L +TRL+IA Sbjct: 706 KHERLVDLHG-------SVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIA 758 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + +G+ +LH + +VHRD+K Sbjct: 759 LDVVEGIRFLH---SQGLVHRDIK 779
>RIPK5_CANFA (Q4VSN4) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 931 Score = 35.8 bits (81), Expect = 0.029 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 8/84 (9%) Frame = +3 Query: 48 RHRNLVSLHGFSLSPNGNLLFYDYMENGSL-----WDLLHGP---SKKVKLDWDTRLRIA 203 +H LV LHG +++ Y+Y S+ + LH K L +TRL+IA Sbjct: 708 KHERLVDLHG-------SVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIA 760 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + +G+ +LH + +VHRD+K Sbjct: 761 LDVVEGIRFLH---SQGLVHRDIK 781
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 35.8 bits (81), Expect = 0.029 Identities = 25/89 (28%), Positives = 47/89 (52%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWD 185 A+ F E + ++HRNLV L G L +G + +++ G+L + L + + + Sbjct: 229 AQAFLDETAVMTKLQHRNLVRLLGVILH-HGLYIVMEHVSKGNLVNFLRTRGRAL-VSTS 286 Query: 186 TRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L+ A+ A+G+ YL + ++VHRD+ Sbjct: 287 QLLQFALHVAEGMEYLE---SKKLVHRDL 312
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 35.8 bits (81), Expect = 0.029 Identities = 23/88 (26%), Positives = 39/88 (44%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 + E+E +RH N++ L+G+ L +Y G+++ L K K D Sbjct: 170 QLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL---QKLSKFDEQRT 226 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 A L+Y H + R++HRD+K Sbjct: 227 ATYITELANALSYCH---SKRVIHRDIK 251
>RIPK5_MOUSE (Q6XUX1) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 927 Score = 35.8 bits (81), Expect = 0.029 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 8/84 (9%) Frame = +3 Query: 48 RHRNLVSLHGFSLSPNGNLLFYDYMENGS-----LWDLLHGP---SKKVKLDWDTRLRIA 203 +H LV LHG +++ Y+Y S + + LH K L +TRL+IA Sbjct: 704 KHERLVDLHG-------SVIDYNYGGGSSVAVLLIMERLHRDLYTGLKAGLTLETRLQIA 756 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + +G+ +LH + +VHRD+K Sbjct: 757 LDVVEGIRFLH---SQGLVHRDIK 777
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 35.8 bits (81), Expect = 0.029 Identities = 23/84 (27%), Positives = 39/84 (46%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + ++ H N+V G + + + +Y ENGSL + K+ + Sbjct: 56 EIDLLKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRSICKNFG---KIPENLVALYT 112 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 QGL YLH N ++HRD+K Sbjct: 113 FQVLQGLLYLH---NQGVIHRDIK 133
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 35.8 bits (81), Expect = 0.029 Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH---GPSKKVKLD 179 R+F +E +G H N++ L G ++ +YMENGSL L G ++L Sbjct: 39 RDFLSEASIMGQFDHPNIIRLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQL- 97 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 + I G A G+ YL + VHRD+ Sbjct: 98 ----VGILRGIASGMKYL---SDMSYVHRDL 121
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 35.8 bits (81), Expect = 0.029 Identities = 23/88 (26%), Positives = 39/88 (44%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTR 191 + E+E +RH N++ L+G+ + L DY G L+ L K + D Sbjct: 184 QLRREVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFREL---QKCTRFDDQRS 240 Query: 192 LRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 A+ L Y H + +++HRD+K Sbjct: 241 ALYIKQLAEALLYCH---SKKVIHRDIK 265
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 35.8 bits (81), Expect = 0.029 Identities = 25/89 (28%), Positives = 47/89 (52%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWD 185 A+ F E + ++HRNLV L G L +G + +++ G+L + L + + + Sbjct: 268 AQAFLDETAVMTKLQHRNLVRLLGVILH-HGLYIVMEHVSKGNLVNFLRTRGRAL-VSTS 325 Query: 186 TRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 L+ A+ A+G+ YL + ++VHRD+ Sbjct: 326 QLLQFALHVAEGMEYLE---SKKLVHRDL 351
>STK36_HUMAN (Q9NRP7) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 35.8 bits (81), Expect = 0.029 Identities = 28/89 (31%), Positives = 42/89 (47%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R + E+E + +RH N+V + + ++ DY E G L+ +L K L D Sbjct: 46 RNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGK---LPEDQ 101 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 IA L YLH + RI+HRD+K Sbjct: 102 VQAIAAQLVSALYYLH---SHRILHRDMK 127
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 35.4 bits (80), Expect = 0.038 Identities = 27/87 (31%), Positives = 40/87 (45%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + + +RH LV L+ +S + +YM GSL D L G K L + Sbjct: 306 FLQEAQVMKKLRHEKLVQLYAV-VSEEPIYIVIEYMSKGSLLDFLKGEMGKY-LRLPQLV 363 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A G+AY+ VHRD++ Sbjct: 364 DMAAQIASGMAYVE---RMNYVHRDLR 387
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 35.4 bits (80), Expect = 0.038 Identities = 27/87 (31%), Positives = 40/87 (45%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + + +RH LV L+ +S + +YM GSL D L G K L + Sbjct: 306 FLQEAQVMKKLRHEKLVQLYAV-VSEEPIYIVIEYMSKGSLLDFLKGEMGKY-LRLPQLV 363 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A G+AY+ VHRD++ Sbjct: 364 DMAAQIASGMAYVE---RMNYVHRDLR 387
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 35.4 bits (80), Expect = 0.038 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 3/91 (3%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH---GPSKKVKLD 179 REF +E +G H N++ L G + ++ ++MENG+L L G ++L Sbjct: 659 REFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQL- 717 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 + + G A G+ YL VHRD+ Sbjct: 718 ----VGMLRGIASGMRYL---AEMSYVHRDL 741
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 35.4 bits (80), Expect = 0.038 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 3/91 (3%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH---GPSKKVKLD 179 R+F +E +G H N++ L G + ++ ++MENGSL L G ++L Sbjct: 666 RDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDSFLRQNDGQFTVIQL- 724 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 + + G A G+ YL + VHRD+ Sbjct: 725 ----VGMLRGIAAGMKYL---ADMNYVHRDL 748
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 35.4 bits (80), Expect = 0.038 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 3/91 (3%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH---GPSKKVKLD 179 R+F +E +G H N++ L G + ++ ++MENGSL L G ++L Sbjct: 683 RDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDSFLRQNDGQFTVIQL- 741 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 + + G A G+ YL + VHRD+ Sbjct: 742 ----VGMLRGIAAGMKYL---ADMNYVHRDL 765
>ULK2_HUMAN (Q8IYT8) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) Length = 1036 Score = 35.4 bits (80), Expect = 0.038 Identities = 25/84 (29%), Positives = 38/84 (45%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + ++H N+V+L+ PN L +Y G L D L K L DT Sbjct: 56 EIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQA---KGTLSEDTIRVFL 112 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 A + LH + I+HRD+K Sbjct: 113 HQIAAAMRILH---SKGIIHRDLK 133
>HOG1_CANAL (Q92207) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 377 Score = 35.4 bits (80), Expect = 0.038 Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG-PSKKVKLDW 182 A+ EL+ + ++H NL++L +SP ++ F + ++ L LL+ P +K + + Sbjct: 64 AKRTYRELKLLKHLKHENLITLDDIFISPLEDIYFVNELQGTDLHRLLNSRPLEKQFIQY 123 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 T +GL Y+H + ++HRD+K Sbjct: 124 FT-----YQIMRGLKYIH---SAGVIHRDLK 146
>AVR2A_XENLA (P27039) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type II) (ACTR-II) Length = 514 Score = 35.4 bits (80), Expect = 0.038 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 13/99 (13%) Frame = +3 Query: 18 ETELETVGSIRHRNLVSLHGFSLSPNGNLLFYD------YMENGSLWDLLHGPSKKVKLD 179 E E+ ++ ++H N+ L+ G L D + E GSL D L K + Sbjct: 233 EYEIYSLPGMKHENI--LYFIGAEKRGTNLDTDLWLITAFHEKGSLTDYL----KANVVS 286 Query: 180 WDTRLRIAVGAAQGLAYLHHDC-------NPRIVHRDVK 275 W+ IA A+GL++LH D P + HRD+K Sbjct: 287 WNELCLIAETMARGLSHLHEDIPGLKDGHKPAVAHRDIK 325
>CLA4_CANAL (O14427) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 971 Score = 35.4 bits (80), Expect = 0.038 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 1/85 (1%) Frame = +3 Query: 24 ELETVGSIRHRNLVS-LHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRI 200 E+ + +H+N+V+ L + + N + +YM+ GSL +++ + KL+ I Sbjct: 726 EILVMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIE--NNDFKLNEKQIATI 783 Query: 201 AVGAAQGLAYLHHDCNPRIVHRDVK 275 +GL +LH I+HRD+K Sbjct: 784 CFETLKGLQHLH---KKHIIHRDIK 805
>RIPK5_BOVIN (Q4TVR5) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 928 Score = 35.4 bits (80), Expect = 0.038 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 8/84 (9%) Frame = +3 Query: 48 RHRNLVSLHGFSLSPNGNLLFYDYMENGSL-----WDLLHGP---SKKVKLDWDTRLRIA 203 +H LV LHG +++ Y Y S+ + LH K L +TRL+IA Sbjct: 705 KHERLVDLHG-------SVIDYSYGGGSSIAVLLIMERLHRDLYTGLKAGLALETRLQIA 757 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 + +G+ +LH + +VHRDVK Sbjct: 758 LDVVEGIRFLH---SQGLVHRDVK 778
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 35.4 bits (80), Expect = 0.038 Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVK-LDWD 185 ++F E + + +RH L+ L+ + + M++GSL + L + K + L Sbjct: 286 KDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQ 345 Query: 186 TRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 T + +A A G+AYL + +HRD+ Sbjct: 346 TLIDMAAQIAAGMAYLE---SQNYIHRDL 371
>ULK2_MOUSE (Q9QY01) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2) Length = 1037 Score = 35.4 bits (80), Expect = 0.038 Identities = 25/84 (29%), Positives = 38/84 (45%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 E++ + ++H N+V+L+ PN L +Y G L D L K L DT Sbjct: 56 EIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQA---KGTLSEDTIRVFL 112 Query: 204 VGAAQGLAYLHHDCNPRIVHRDVK 275 A + LH + I+HRD+K Sbjct: 113 HQIAAAMRILH---SKGIIHRDLK 133
>PR2_DROME (Q9I7F7) Tyrosine-protein kinase PR2 (EC 2.7.10.2)| Length = 1337 Score = 35.4 bits (80), Expect = 0.038 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 1/88 (1%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVK-LDWDT 188 EF E + SI H N+V L+G L+ + +L + SL + L +V L T Sbjct: 177 EFLKEAAIMHSIEHENIVRLYGVVLATDSLMLVTELAHLRSLLECLKDSGLRVSFLTIPT 236 Query: 189 RLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 A+ G+ YL R++HRD+ Sbjct: 237 LCEFALQICNGMRYLE---QKRLIHRDL 261
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 35.0 bits (79), Expect = 0.050 Identities = 27/87 (31%), Positives = 40/87 (45%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + + +RH LV L+ +S + +YM GSL D L G K L + Sbjct: 306 FLQEAQVMKKLRHEKLVQLYAV-VSEEPIYIVTEYMSKGSLLDFLKGEMGKY-LRLPQLV 363 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A G+AY+ VHRD++ Sbjct: 364 DMAAQIASGMAYVE---RMNYVHRDLR 387
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 35.0 bits (79), Expect = 0.050 Identities = 27/87 (31%), Positives = 40/87 (45%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + + +RH LV L+ +S + +YM GSL D L G K L + Sbjct: 306 FLQEAQVMKKLRHEKLVQLYAV-VSEEPIYIVTEYMSKGSLLDFLKGEMGKY-LRLPQLV 363 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A G+AY+ VHRD++ Sbjct: 364 DMAAQIASGMAYVE---RMNYVHRDLR 387
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 35.0 bits (79), Expect = 0.050 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 3/91 (3%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH---GPSKKVKLD 179 REF +E +G H N++ L G + ++ ++MENG+L L G ++L Sbjct: 659 REFLSEASIMGQFEHPNIIRLEGVVTNSVPVMILTEFMENGALDSFLRLNDGQFTVIQL- 717 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 + + G A G+ YL VHRD+ Sbjct: 718 ----VGMLRGIASGMRYL---AEMSYVHRDL 741
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 35.0 bits (79), Expect = 0.050 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 3/91 (3%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH---GPSKKVKLD 179 R+F +E +G H N++ L G ++ ++MENGSL L G ++L Sbjct: 665 RDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL- 723 Query: 180 WDTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 + + G A G+ YL + VHRD+ Sbjct: 724 ----VGMLRGIAAGMKYL---ADMNYVHRDL 747
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 35.0 bits (79), Expect = 0.050 Identities = 27/87 (31%), Positives = 40/87 (45%) Frame = +3 Query: 15 FETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRL 194 F E + + +RH LV L+ +S + +YM GSL D L G K L + Sbjct: 306 FLQEAQVMKKLRHEKLVQLYAV-VSEEPIYIVTEYMSKGSLLDFLKGEMGKY-LRLPQLV 363 Query: 195 RIAVGAAQGLAYLHHDCNPRIVHRDVK 275 +A A G+AY+ VHRD++ Sbjct: 364 DMAAQIASGMAYVE---RMNYVHRDLR 387
>HOG1_DEBHA (Q9UV50) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 387 Score = 35.0 bits (79), Expect = 0.050 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Frame = +3 Query: 6 AREFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHG-PSKKVKLDW 182 A+ EL+ + +RH NL++L LSP ++ F ++ L LL P +K + + Sbjct: 64 AKRTYRELKLLKHLRHENLITLDDIFLSPLEDIYFVTELQGTDLHRLLTSRPLEKQFIQY 123 Query: 183 DTRLRIAVGAAQGLAYLHHDCNPRIVHRDVK 275 T +GL Y+H + ++HRD+K Sbjct: 124 FT-----YQILRGLKYVH---SAGVIHRDLK 146
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 35.0 bits (79), Expect = 0.050 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R+F E +G H N++ L G ++ +YMENGSL L K D Sbjct: 665 RDFLGEASIMGQFDHPNIIRLEGVVTKSKPEMIVTEYMENGSLDSFLR------KHDAQF 718 Query: 189 RLRIAVGAAQGLAY-LHHDCNPRIVHRDV 272 + VG +G+A + + + VHRD+ Sbjct: 719 TVIQLVGMLRGIASGMKYLSDMGYVHRDL 747
>ANPRB_ANGJA (P55202) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1050 Score = 35.0 bits (79), Expect = 0.050 Identities = 20/77 (25%), Positives = 36/77 (46%) Frame = +3 Query: 9 REFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDT 188 R+ EL+ + ++ +L G + P + +Y GSL D+L S + LDW Sbjct: 566 RQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENES--INLDWMF 623 Query: 189 RLRIAVGAAQGLAYLHH 239 R + +G+ +LH+ Sbjct: 624 RYSLINDIVKGMNFLHN 640
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 35.0 bits (79), Expect = 0.050 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 7/94 (7%) Frame = +3 Query: 12 EFETELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLH-------GPSKKV 170 +F E + RH+N+V G SL L+ + M G + L PS V Sbjct: 557 DFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLV 616 Query: 171 KLDWDTRLRIAVGAAQGLAYLHHDCNPRIVHRDV 272 D L++A AQG YL + +HRD+ Sbjct: 617 MRD---LLQLAQDIAQGCHYLEEN---HFIHRDI 644
>ANPRA_RAT (P18910) Atrial natriuretic peptide receptor A precursor (ANP-A)| (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor) Length = 1057 Score = 35.0 bits (79), Expect = 0.050 Identities = 19/72 (26%), Positives = 34/72 (47%) Frame = +3 Query: 24 ELETVGSIRHRNLVSLHGFSLSPNGNLLFYDYMENGSLWDLLHGPSKKVKLDWDTRLRIA 203 EL+ + +++ +L G P + +Y GSL D+L S + LDW R + Sbjct: 579 ELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENES--ITLDWMFRYSLT 636 Query: 204 VGAAQGLAYLHH 239 +G+ +LH+ Sbjct: 637 NDIVKGMLFLHN 648 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 46,869,907 Number of Sequences: 219361 Number of extensions: 980340 Number of successful extensions: 3235 Number of sequences better than 10.0: 463 Number of HSP's better than 10.0 without gapping: 3083 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3163 length of database: 80,573,946 effective HSP length: 67 effective length of database: 65,876,759 effective search space used: 1581042216 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
