ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bast09d12 |
|---|---|
| Clone Library Name | barley_pub |
>G11A_ORYSA (P47997) Protein kinase G11A (EC 2.7.11.1)| Length = 589 Score = 159 bits (401), Expect = 3e-39 Identities = 77/110 (70%), Positives = 89/110 (80%) Frame = +2 Query: 89 DPRWKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDK 268 D RW+A+ R DG LG+ F+LL++LGCGDIG+VYLSELS G +FAMKVMDK Sbjct: 174 DSRWEAIQMIRTRDGILGLSHFKLLKKLGCGDIGSVYLSELS-----GTKSYFAMKVMDK 228 Query: 269 ASLESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ASL SR+KL RA+TE+EILQ LDHPFLPTLY HFETDKF+CLVMEFCPGG Sbjct: 229 ASLASRKKLLRAQTEKEILQCLDHPFLPTLYTHFETDKFSCLVMEFCPGG 278
>KPK1_PHAVU (P15792) Protein kinase PVPK-1 (EC 2.7.11.1)| Length = 609 Score = 146 bits (368), Expect = 2e-35 Identities = 73/110 (66%), Positives = 85/110 (77%) Frame = +2 Query: 89 DPRWKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDK 268 D RW+A+ A R DG L M FRLL++LGCGDIG+VYL+ELS G FAMKVM+K Sbjct: 208 DIRWEAIQAVRTRDGMLEMRHFRLLKKLGCGDIGSVYLAELS-----GTRTSFAMKVMNK 262 Query: 269 ASLESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L +R+KL RA+TEREILQ LDHPFLPTLY HFET+ F+CLVMEFCPGG Sbjct: 263 TELANRKKLLRAQTEREILQSLDHPFLPTLYTHFETEIFSCLVMEFCPGG 312
>KPK7_ARATH (Q05999) Putative serine/threonine-protein kinase PK7 (EC 2.7.11.1)| Length = 578 Score = 125 bits (314), Expect = 4e-29 Identities = 68/138 (49%), Positives = 87/138 (63%), Gaps = 1/138 (0%) Frame = +2 Query: 8 SAASDWSNXXXXXXXXXXXXXXXXXXXDPRWKAVLAARAGDGP-LGMGDFRLLRRLGCGD 184 S SD S+ D RW A+ R+ G L DF+L+++LG GD Sbjct: 133 SIGSDVSDESSSSGLSNAAYKPHRDNNDKRWVAIQEVRSRVGSSLEAKDFKLIKKLGGGD 192 Query: 185 IGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQLLDHPFLPTLYA 364 IG VYL+EL G FA+KVM+KA++ +R+KL RA+TE+EILQ LDHPFLPTLY+ Sbjct: 193 IGNVYLAEL-----IGTGVSFAVKVMEKAAIAARKKLVRAQTEKEILQSLDHPFLPTLYS 247 Query: 365 HFETDKFACLVMEFCPGG 418 HFET+ +CLVMEFCPGG Sbjct: 248 HFETEMNSCLVMEFCPGG 265
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 101 bits (251), Expect = 8e-22 Identities = 50/107 (46%), Positives = 67/107 (62%) Frame = +2 Query: 98 WKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASL 277 WKA+ +A +G+ F+ ++ LG GD G+V+L EL G +AMK M+K + Sbjct: 559 WKAIKKIQASGETVGLHHFKPIKPLGSGDTGSVHLVELK-----GTGELYAMKAMEKTMM 613 Query: 278 ESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +R K RA EREI+ LLDHPFLPTLYA F+T CL+ +FCPGG Sbjct: 614 LNRNKAHRACIEREIISLLDHPFLPTLYASFQTSTHVCLITDFCPGG 660
>PHOT1_ARATH (O48963) Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl| protein 1) (Root phototropism protein 1) Length = 996 Score = 99.0 bits (245), Expect = 4e-21 Identities = 51/109 (46%), Positives = 66/109 (60%) Frame = +2 Query: 92 PRWKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKA 271 P W A+ P+G+ F+ ++ LG GD G+V+L EL G FAMK MDKA Sbjct: 643 PPWIAIQKVLESGEPIGLKHFKPVKPLGSGDTGSVHLVEL-----VGTDQLFAMKAMDKA 697 Query: 272 SLESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + +R K+ RA EREIL LLDHPFLP LYA F+T CL+ ++ PGG Sbjct: 698 VMLNRNKVHRARAEREILDLLDHPFLPALYASFQTKTHICLITDYYPGG 746
>NRC2_NEUCR (O42626) Serine/threonine-protein kinase nrc-2 (EC 2.7.11.1)| (Nonrepressible conidiation protein 2) Length = 623 Score = 72.0 bits (175), Expect = 5e-13 Identities = 37/94 (39%), Positives = 55/94 (58%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 +G F ++ +G GD+G VYL + K G +AMKV+ K + R K+ RA E+ Sbjct: 237 VGPQSFDKIKLIGKGDVGKVYLVKEKKSGRL-----YAMKVLSKKEMIKRNKIKRALAEQ 291 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 EIL +HPF+ TLY F+++ + L ME+C GG Sbjct: 292 EILATSNHPFIVTLYHSFQSEDYLYLCMEYCSGG 325
>KAD5_SCHPO (Q09831) Probable serine/threonine-protein kinase C4G8.05 (EC| 2.7.11.1) Length = 566 Score = 72.0 bits (175), Expect = 5e-13 Identities = 39/97 (40%), Positives = 54/97 (55%) Frame = +2 Query: 128 DGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAE 307 D +G F + LG GD+G VYL K G ++AMKV+ K + R K RA Sbjct: 187 DVEVGPSSFEKVFLLGKGDVGRVYLVREKKSG-----KFYAMKVLSKQEMIKRNKSKRAF 241 Query: 308 TEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 E+ IL +HPF+ TLY F++D++ L ME+C GG Sbjct: 242 AEQHILATSNHPFIVTLYHSFQSDEYLYLCMEYCMGG 278
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 70.9 bits (172), Expect = 1e-12 Identities = 38/89 (42%), Positives = 51/89 (57%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F +R LG GD+G VYL FA+KV++K + R+K+ R TE+EIL Sbjct: 324 FEKIRLLGQGDVGKVYLMRERDTNQI-----FALKVLNKHEMIKRKKIKRVLTEQEILAT 378 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 DHPF+ TLY F+T + L ME+C GG Sbjct: 379 SDHPFIVTLYHSFQTKDYLYLCMEYCMGG 407
>KN8R_YEAST (P53739) Probable serine/threonine-protein kinase YNR047W (EC| 2.7.11.1) Length = 893 Score = 68.6 bits (166), Expect = 6e-12 Identities = 36/94 (38%), Positives = 53/94 (56%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 +G F +R LG GD+G V+L K +A+KV+ K + R K+ R TE+ Sbjct: 491 VGPQSFEKIRLLGQGDVGKVFLVREKKTNRV-----YALKVLSKDEMIKRNKIKRVLTEQ 545 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 EIL +HPF+ TLY F+++ + L ME+C GG Sbjct: 546 EILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGG 579
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 62.4 bits (150), Expect = 4e-10 Identities = 36/89 (40%), Positives = 57/89 (64%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F LL+ LG G G V+L KG AG+ +AMKV+ KA+L+ R ++ R++ ER+IL Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQL--YAMKVLKKATLKVRDRV-RSKMERDILAE 115 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++HPF+ L+ F+T+ L+++F GG Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGG 144 Score = 30.0 bits (66), Expect = 2.3 Identities = 19/58 (32%), Positives = 30/58 (51%) Frame = +2 Query: 245 FAMKVMDKASLESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +A+K++DK+ K +E +L+ HP + TL ++ KF LVME GG Sbjct: 441 YAVKIIDKS------KRDPSEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGG 492
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 60.8 bits (146), Expect = 1e-09 Identities = 36/89 (40%), Positives = 55/89 (61%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F LL+ LG G G V+L G AG+ +AMKV+ KASL+ R ++ R + ER+IL Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQL--YAMKVLKKASLKVRDRV-RTKMERDILVE 129 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++HPF+ L+ F+T+ L+++F GG Sbjct: 130 VNHPFIVKLHYAFQTEGKLYLILDFLRGG 158
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 60.1 bits (144), Expect = 2e-09 Identities = 35/89 (39%), Positives = 56/89 (62%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F LL+ LG G G V+L G AG+ +AMKV+ KA+L+ R ++ R++ ER+IL Sbjct: 59 FELLKVLGQGSYGKVFLVRKVTGSDAGQL--YAMKVLKKATLKVRDRV-RSKMERDILAE 115 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++HPF+ L+ F+T+ L+++F GG Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGG 144 Score = 28.9 bits (63), Expect = 5.0 Identities = 18/58 (31%), Positives = 30/58 (51%) Frame = +2 Query: 245 FAMKVMDKASLESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +A+K++DK+ K +E +L+ HP + TL ++ K+ LVME GG Sbjct: 441 YAVKIIDKS------KRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVMELMRGG 492
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 58.5 bits (140), Expect = 6e-09 Identities = 37/92 (40%), Positives = 53/92 (57%), Gaps = 2/92 (2%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSR-AETEREIL 325 +F LL+ LG G G V+L + K GG +AMKV+ KA+L R K TER +L Sbjct: 32 NFELLKVLGTGAYGKVFL--VRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVL 89 Query: 326 QLLDH-PFLPTLYAHFETDKFACLVMEFCPGG 418 +L+ PFL TL+ F+TD L++++ GG Sbjct: 90 ELVRQAPFLVTLHYAFQTDAKLHLILDYVSGG 121
>PKN3_HUMAN (Q6P5Z2) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 889 Score = 58.2 bits (139), Expect = 8e-09 Identities = 36/98 (36%), Positives = 50/98 (51%), Gaps = 3/98 (3%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P + DFR L LG G G V L + G ++A+K + K + SR ++ E Sbjct: 553 PPRLQDFRCLAVLGRGHFGKVLLVQFK-----GTGKYYAIKALKKQEVLSRDEIESLYCE 607 Query: 314 REILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 + IL+ + HPFL +L A F+T AC V EF PGG Sbjct: 608 KRILEAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGG 645
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 58.2 bits (139), Expect = 8e-09 Identities = 34/89 (38%), Positives = 52/89 (58%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F LL+ LG G G V+L +G +G +AMKV+ KA+L+ R + R + ER IL Sbjct: 104 FELLKVLGQGSFGKVFLVRKVRGRDSGHV--YAMKVLKKATLKVRDR-QRTKLERNILAH 160 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + HPF+ L+ F+T+ L+++F GG Sbjct: 161 ISHPFIVKLHYAFQTEGKLYLILDFLRGG 189
>PKN1_RAT (Q63433) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protease-activated kinase 1) (PAK-1) Length = 946 Score = 58.2 bits (139), Expect = 8e-09 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 3/98 (3%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 PL + DF+ L LG G G V LSE G FA+K + K + +R ++ E Sbjct: 613 PLTLEDFKFLAVLGRGHFGKVLLSEFHSSGEL-----FAIKALKKGDIVARDEVESLMCE 667 Query: 314 REILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 + IL + HPFL L+ F+T + C VME+ GG Sbjct: 668 KRILATVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGG 705
>PKN1_MOUSE (P70268) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) Length = 946 Score = 58.2 bits (139), Expect = 8e-09 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 3/98 (3%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 PL + DF+ L LG G G V LSE G FA+K + K + +R ++ E Sbjct: 613 PLTLEDFKFLAVLGRGHFGKVLLSEFRSSGEL-----FAIKALKKGDIVARDEVESLMCE 667 Query: 314 REILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 + IL + HPFL L+ F+T + C VME+ GG Sbjct: 668 KRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGG 705
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 57.8 bits (138), Expect = 1e-08 Identities = 30/90 (33%), Positives = 51/90 (56%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 +F+ +R LG G G VYL + +K G ++AMK ++KA + +++ +E+ IL Sbjct: 335 EFKQIRVLGTGTFGKVYLIQNTKDGC-----YYAMKCLNKAYVVQLKQVEHLNSEKSILS 389 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + HPF+ LY F+ +K L+ E+ GG Sbjct: 390 SIHHPFIVNLYQAFQDEKKLYLLFEYVAGG 419
>PKN1_HUMAN (Q16512) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha) Length = 942 Score = 57.8 bits (138), Expect = 1e-08 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 3/98 (3%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 PL + DF+ L LG G G V LSE G FA+K + K + +R ++ E Sbjct: 609 PLTLEDFKFLAVLGRGHFGKVLLSEFRPSGEL-----FAIKALKKGDIVARDEVESLMCE 663 Query: 314 REILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 + IL + HPFL L+ F+T + C VME+ GG Sbjct: 664 KRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGG 701
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 57.8 bits (138), Expect = 1e-08 Identities = 32/89 (35%), Positives = 47/89 (52%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F LR LG G G V L + GG +AMK+++K + +++ E+ ILQ Sbjct: 43 FERLRTLGMGSFGRVMLVRHQETGGH-----YAMKILNKQKVVKMKQVEHILNEKRILQA 97 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +D PFL L F+ + + LVME+ PGG Sbjct: 98 IDFPFLVKLQFSFKDNSYLYLVMEYVPGG 126
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 57.8 bits (138), Expect = 1e-08 Identities = 37/92 (40%), Positives = 54/92 (58%), Gaps = 2/92 (2%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSR-AETEREIL 325 +F LL+ LG G G V+L + G AG+ +AMKV+ KA+L R K TER +L Sbjct: 32 NFALLKVLGTGAYGKVFLVRKTGGHDAGKL--YAMKVLRKAALVQRAKTQEHTRTERSVL 89 Query: 326 QLLDH-PFLPTLYAHFETDKFACLVMEFCPGG 418 +L+ PFL TL+ F+TD L++++ GG Sbjct: 90 ELVRQAPFLVTLHYAFQTDAKLHLILDYVSGG 121
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 57.8 bits (138), Expect = 1e-08 Identities = 34/89 (38%), Positives = 55/89 (61%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F LL+ LG G G V+L + K G+ +AMKV+ KA+L+ R ++ R + ER+IL Sbjct: 68 FELLKVLGQGSFGKVFL--VKKISGSDARQLYAMKVLKKATLKVRDRV-RTKMERDILVE 124 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++HPF+ L+ F+T+ L+++F GG Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGG 153
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 57.8 bits (138), Expect = 1e-08 Identities = 34/89 (38%), Positives = 55/89 (61%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F LL+ LG G G V+L + K G+ +AMKV+ KA+L+ R ++ R + ER+IL Sbjct: 68 FELLKVLGQGSFGKVFL--VKKISGSDARQLYAMKVLKKATLKVRDRV-RTKMERDILVE 124 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++HPF+ L+ F+T+ L+++F GG Sbjct: 125 VNHPFIVKLHYAFQTEGKLYLILDFLRGG 153
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 57.8 bits (138), Expect = 1e-08 Identities = 35/96 (36%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSR-AETE 313 +G+ +F LL+ LG G G V+L G AG+ +AMKV+ KA++ + K + TE Sbjct: 34 VGIENFELLKVLGTGAYGKVFLVRKVSGHDAGKL--YAMKVLKKATIVQKAKTTEHTRTE 91 Query: 314 REILQ-LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R++L+ + PFL TL+ F+TD L++++ GG Sbjct: 92 RQVLEHIRQSPFLVTLHYAFQTDTKLHLILDYINGG 127
>PKN3_MOUSE (Q8K045) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 878 Score = 57.4 bits (137), Expect = 1e-08 Identities = 41/115 (35%), Positives = 56/115 (48%), Gaps = 5/115 (4%) Frame = +2 Query: 89 DPRWKAV--LAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVM 262 DPR V LAA + P + DFR L LG G G V L + G ++A+K + Sbjct: 525 DPRPAVVPALAALSTRKPPRLQDFRCLAVLGRGHFGKVLLVQYK-----GTGKYYAIKAL 579 Query: 263 DKASLESRRKLSRAETEREILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 K + R ++ E+ IL+ + HPFL +L A +T AC V EF PGG Sbjct: 580 KKQEVLGRDEIDSLYCEKRILETVGRTGHPFLLSLLACLQTSSHACFVTEFLPGG 634
>MAST1_RAT (Q810W7) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 56.6 bits (135), Expect = 2e-08 Identities = 32/95 (33%), Positives = 50/95 (52%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P G DF ++ + G G VYL FAMK ++K +L R ++ +A E Sbjct: 370 PPGESDFDTIKLISNGAYGAVYLVR-----HRDTRQRFAMKKINKQNLILRNQIQQAFVE 424 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R+IL ++PF+ ++ FET + C+VME+ GG Sbjct: 425 RDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGG 459
>MAST1_HUMAN (Q9Y2H9) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 56.6 bits (135), Expect = 2e-08 Identities = 32/95 (33%), Positives = 50/95 (52%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P G DF ++ + G G VYL FAMK ++K +L R ++ +A E Sbjct: 368 PPGENDFDTIKLISNGAYGAVYLVR-----HRDTRQRFAMKKINKQNLILRNQIQQAFVE 422 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R+IL ++PF+ ++ FET + C+VME+ GG Sbjct: 423 RDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGG 457
>MAST1_MOUSE (Q9R1L5) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1566 Score = 56.6 bits (135), Expect = 2e-08 Identities = 32/95 (33%), Positives = 50/95 (52%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P G DF ++ + G G VYL FAMK ++K +L R ++ +A E Sbjct: 369 PPGESDFDTIKLISNGAYGAVYLVR-----HRDTRQRFAMKKINKQNLILRNQIQQAFVE 423 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R+IL ++PF+ ++ FET + C+VME+ GG Sbjct: 424 RDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGG 458
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 56.2 bits (134), Expect = 3e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSR-AETE 313 +G+ +F LL+ LG G G V+L G AG+ +AMKV+ KA++ + K + TE Sbjct: 43 VGIENFELLKVLGTGAYGKVFLVRKISGHDAGKL--YAMKVLKKATIVQKAKTTEHTRTE 100 Query: 314 REILQ-LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R++L+ + PFL TL+ F+T+ L++++ GG Sbjct: 101 RQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGG 136
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 55.8 bits (133), Expect = 4e-08 Identities = 35/100 (35%), Positives = 56/100 (56%) Frame = +2 Query: 119 RAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLS 298 +AG F LL+ LG G G V+L +G +AMKV+ KA+L+ R ++ Sbjct: 51 KAGSEKADPSQFELLKVLGQGSFGKVFLVRKVTRPDSGHL--YAMKVLKKATLKVRDRV- 107 Query: 299 RAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R + ER+IL ++HPF+ L+ F+T+ L+++F GG Sbjct: 108 RTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGG 147
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 55.5 bits (132), Expect = 5e-08 Identities = 35/100 (35%), Positives = 56/100 (56%) Frame = +2 Query: 119 RAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLS 298 +AG F LL+ LG G G V+L +G +AMKV+ KA+L+ R ++ Sbjct: 51 KAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHL--YAMKVLKKATLKVRDRV- 107 Query: 299 RAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R + ER+IL ++HPF+ L+ F+T+ L+++F GG Sbjct: 108 RTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGG 147
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 55.5 bits (132), Expect = 5e-08 Identities = 29/104 (27%), Positives = 53/104 (50%) Frame = +2 Query: 107 VLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESR 286 + AR G + DF++LR LG G G V+L G ++AMKV+ K + Sbjct: 72 IAQARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGR-----YYAMKVLKKEIVVRL 126 Query: 287 RKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +++ ER +L ++ HPF+ ++ F+ + ++M++ GG Sbjct: 127 KQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGG 170
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 55.1 bits (131), Expect = 7e-08 Identities = 34/103 (33%), Positives = 50/103 (48%) Frame = +2 Query: 110 LAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRR 289 +A G + M DF L+ LG G G V L G ++AMK++ K + ++ Sbjct: 143 VAMSKGHPKVTMNDFDYLKLLGKGTFGKVILVREKATGR-----YYAMKILRKEVIIAKD 197 Query: 290 KLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +++ TE +LQ HPFL L F+T C VME+ GG Sbjct: 198 EVAHTLTESRVLQNTKHPFLTALKYAFQTSDRLCFVMEYANGG 240
>MAST2_MOUSE (Q60592) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1734 Score = 54.7 bits (130), Expect = 9e-08 Identities = 29/90 (32%), Positives = 49/90 (54%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF ++ + G G V+L FAMK ++K +L R ++ +A ER+IL Sbjct: 452 DFETIKLISNGAYGAVFLVRHKS-----TRQRFAMKKINKQNLILRNQIQQAFVERDILT 506 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++PF+ +++ FET + C+VME+ GG Sbjct: 507 FAENPFVVSMFCSFETKRHLCMVMEYVEGG 536
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 54.7 bits (130), Expect = 9e-08 Identities = 33/92 (35%), Positives = 48/92 (52%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M +F L+ LG G G V L K GR ++AMK++ K + ++ +++ TE + Sbjct: 148 MNEFEYLKLLGKGTFGKVILV---KEKATGR--YYAMKILKKEVIVAKDEVAHTLTENRV 202 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ HPFL L F+T C VME+ GG Sbjct: 203 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGG 234
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 54.7 bits (130), Expect = 9e-08 Identities = 33/92 (35%), Positives = 48/92 (52%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M +F L+ LG G G V L K GR ++AMK++ K + ++ +++ TE + Sbjct: 168 MNEFEYLKLLGKGTFGKVILV---KEKATGR--YYAMKILKKEVIVAKDEVAHTLTENRV 222 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ HPFL L F+T C VME+ GG Sbjct: 223 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGG 254
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 54.7 bits (130), Expect = 9e-08 Identities = 35/100 (35%), Positives = 56/100 (56%) Frame = +2 Query: 119 RAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLS 298 +AG F LL+ LG G G V+L + K +AMKV+ KA+L+ R ++ Sbjct: 51 KAGSEKADPSHFELLKVLGQGSFGKVFL--VRKVTRPDNGHLYAMKVLKKATLKVRDRV- 107 Query: 299 RAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R + ER+IL ++HPF+ L+ F+T+ L+++F GG Sbjct: 108 RTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGG 147
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 54.7 bits (130), Expect = 9e-08 Identities = 33/99 (33%), Positives = 58/99 (58%), Gaps = 2/99 (2%) Frame = +2 Query: 128 DGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLS-RA 304 D + + DF+++R LG G G V+L AG+ +AMKV++K ++ +RK + Sbjct: 253 DEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKL--YAMKVLNKITVVQKRKTAEHT 310 Query: 305 ETEREILQLLD-HPFLPTLYAHFETDKFACLVMEFCPGG 418 +TER +L+ + +PFL +L+ F++ LV++F GG Sbjct: 311 KTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGG 349
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 54.7 bits (130), Expect = 9e-08 Identities = 33/92 (35%), Positives = 48/92 (52%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M +F L+ LG G G V L K GR ++AMK++ K + ++ +++ TE + Sbjct: 147 MNEFEYLKLLGKGTFGKVILV---KEKATGR--YYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ HPFL L F+T C VME+ GG Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGG 233
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 54.7 bits (130), Expect = 9e-08 Identities = 33/92 (35%), Positives = 48/92 (52%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M +F L+ LG G G V L K GR ++AMK++ K + ++ +++ TE + Sbjct: 147 MNEFEYLKLLGKGTFGKVILV---KEKATGR--YYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ HPFL L F+T C VME+ GG Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGG 233
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 54.7 bits (130), Expect = 9e-08 Identities = 33/92 (35%), Positives = 48/92 (52%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M +F L+ LG G G V L K GR ++AMK++ K + ++ +++ TE + Sbjct: 147 MNEFEYLKLLGKGTFGKVILV---KEKATGR--YYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ HPFL L F+T C VME+ GG Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGG 233
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 54.7 bits (130), Expect = 9e-08 Identities = 33/96 (34%), Positives = 56/96 (58%), Gaps = 2/96 (2%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSR-AETE 313 +G+ +F LL+ LG G G V+L G G+ +AMKV+ KA++ + K + TE Sbjct: 44 VGIENFELLKVLGTGAYGKVFLVRKISGHDTGKL--YAMKVLKKATIVQKAKTTEHTRTE 101 Query: 314 REILQ-LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R++L+ + PFL TL+ F+T+ L++++ GG Sbjct: 102 RQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGG 137
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 54.3 bits (129), Expect = 1e-07 Identities = 37/105 (35%), Positives = 52/105 (49%) Frame = +2 Query: 104 AVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLES 283 AV ARA + M DF L+ LG G G V L G ++AMK++ K + + Sbjct: 139 AVSKARA---KVTMNDFDYLKLLGKGTFGKVILVREKATGR-----YYAMKILRKEVIIA 190 Query: 284 RRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + +++ TE +LQ HPFL L F+T C VME+ GG Sbjct: 191 KDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGG 235
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 54.3 bits (129), Expect = 1e-07 Identities = 37/105 (35%), Positives = 52/105 (49%) Frame = +2 Query: 104 AVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLES 283 AV ARA + M DF L+ LG G G V L G ++AMK++ K + + Sbjct: 139 AVSKARA---KVTMNDFDYLKLLGKGTFGKVILVREKATGR-----YYAMKILRKEVIIA 190 Query: 284 RRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + +++ TE +LQ HPFL L F+T C VME+ GG Sbjct: 191 KDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGG 235
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 54.3 bits (129), Expect = 1e-07 Identities = 29/93 (31%), Positives = 49/93 (52%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G+ DF L+ LG G G V+L + + ++A+KV++K + +++ ER Sbjct: 197 GIQDFNFLQTLGTGSFGRVHLVQSNHN-----RLYYAIKVLEKKKIVDMKQIEHTCDERY 251 Query: 320 ILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 IL + HPF+ L+ F+ K +VM+F GG Sbjct: 252 ILSRVQHPFITILWGTFQDAKNLFMVMDFAEGG 284
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 54.3 bits (129), Expect = 1e-07 Identities = 31/90 (34%), Positives = 52/90 (57%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF LL +G G G V ++ K G FAMKV+ K ++ +R++++ ++E+ ILQ Sbjct: 152 DFELLNVIGKGSFGKVM--QVKK---KGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQ 206 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + HPF+ L+ F+T +V++F GG Sbjct: 207 CISHPFIVNLHYAFQTKDKLYMVLDFVNGG 236
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 54.3 bits (129), Expect = 1e-07 Identities = 35/100 (35%), Positives = 55/100 (55%) Frame = +2 Query: 119 RAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLS 298 + G DF LL+ LG G G V+L A + +AMKV+ KA+L+ R ++ Sbjct: 51 KEGSEKADQSDFVLLKVLGQGSFGKVFLVRKITPPDANQL--YAMKVLKKATLKVRDRV- 107 Query: 299 RAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R + ER+IL + HPF+ L+ F+T+ L+++F GG Sbjct: 108 RTKMERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGG 147
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 53.9 bits (128), Expect = 1e-07 Identities = 37/105 (35%), Positives = 52/105 (49%) Frame = +2 Query: 104 AVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLES 283 AV ARA + M DF L+ LG G G V L G ++AMK++ K + + Sbjct: 139 AVNKARA---KVTMNDFDYLKLLGKGTFGKVILVREKATGR-----YYAMKILRKEVIIA 190 Query: 284 RRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + +++ TE +LQ HPFL L F+T C VME+ GG Sbjct: 191 KDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGG 235
>CBK1_KLULA (P31034) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 718 Score = 53.9 bits (128), Expect = 1e-07 Identities = 29/94 (30%), Positives = 52/94 (55%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF ++ +G G G V L + G +AMK + K+ + ++ +L+ + ER Sbjct: 298 LSLDDFNSVKVIGKGAFGEVRLVQKKDTGKI-----YAMKTLLKSEMYNKDQLAHVKAER 352 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++L D P++ +LY F+ ++ L+MEF PGG Sbjct: 353 DVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGG 386
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 53.5 bits (127), Expect = 2e-07 Identities = 31/92 (33%), Positives = 47/92 (51%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M DF L+ LG G G V L G ++AMK++ K + ++ +++ TE + Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASG-----KYYAMKILKKEVIIAKDEVAHTLTESRV 199 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L+ HPFL +L F+T C VME+ GG Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGG 231
>CBK1_PNECA (Q6TGC6) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 507 Score = 53.5 bits (127), Expect = 2e-07 Identities = 29/94 (30%), Positives = 51/94 (54%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF ++ +G G G V L + G +AMK + K+ + + +L+ + ER Sbjct: 121 LSLNDFHTVKVIGKGAFGEVRLVQKIDTGKI-----YAMKTLLKSEMFKKDQLAHVKAER 175 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++L D P++ +LY F+ ++ L+MEF PGG Sbjct: 176 DVLAESDSPWVVSLYYSFQDSQYLYLIMEFLPGG 209
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 53.5 bits (127), Expect = 2e-07 Identities = 34/103 (33%), Positives = 50/103 (48%) Frame = +2 Query: 110 LAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRR 289 +A G + M DF L+ LG G G V L G ++AMK++ K + ++ Sbjct: 142 VAMSKGRPKVTMNDFDYLKLLGKGTFGKVILVREKATG-----LYYAMKILRKEVIIAKD 196 Query: 290 KLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +++ TE +LQ HPFL L F+T C VME+ GG Sbjct: 197 EVAHTLTESRVLQNTKHPFLTGLKYAFQTSDRLCFVMEYANGG 239
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 53.5 bits (127), Expect = 2e-07 Identities = 31/92 (33%), Positives = 47/92 (51%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M DF L+ LG G G V L G ++AMK++ K + ++ +++ TE + Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASG-----KYYAMKILKKEVIIAKDEVAHTLTESRV 199 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L+ HPFL +L F+T C VME+ GG Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGG 231
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 53.5 bits (127), Expect = 2e-07 Identities = 31/92 (33%), Positives = 47/92 (51%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M DF L+ LG G G V L G ++AMK++ K + ++ +++ TE + Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASG-----KYYAMKILKKEVIIAKDEVAHTLTESRV 199 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L+ HPFL +L F+T C VME+ GG Sbjct: 200 LKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGG 231
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 53.5 bits (127), Expect = 2e-07 Identities = 27/92 (29%), Positives = 48/92 (52%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 + DF ++ LG G G V + + ++AMK++DK + +++ E+ I Sbjct: 42 LDDFERIKTLGTGSFGRVMIVQHKP-----TKDYYAMKILDKQKVVKLKQVEHTLNEKRI 96 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ + PFL +L HF+ + +V+E+ PGG Sbjct: 97 LQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGG 128
>CBK1_YARLI (Q6CFS5) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 588 Score = 53.5 bits (127), Expect = 2e-07 Identities = 29/94 (30%), Positives = 50/94 (53%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 + + DF ++ +G G G V L + G +AMK M K ++ + + + + ER Sbjct: 202 MALEDFVTVKVIGKGAFGEVRLVQKRDNGKI-----YAMKTMLKKEMDMKEQWAHVKAER 256 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++L D P++ +LY F+ D + L+MEF PGG Sbjct: 257 DVLADSDSPWIVSLYFSFQDDLYLYLIMEFLPGG 290
>MAST2_HUMAN (Q6P0Q8) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1798 Score = 53.5 bits (127), Expect = 2e-07 Identities = 28/90 (31%), Positives = 49/90 (54%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF ++ + G G V+L FAMK ++K +L R ++ +A ER+IL Sbjct: 511 DFETIKLISNGAYGAVFLVRHKS-----TRQRFAMKKINKQNLILRNQIQQAFVERDILT 565 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++PF+ +++ F+T + C+VME+ GG Sbjct: 566 FAENPFVVSMFCSFDTKRHLCMVMEYVEGG 595
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 53.5 bits (127), Expect = 2e-07 Identities = 33/96 (34%), Positives = 55/96 (57%), Gaps = 2/96 (2%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSR-AETE 313 +G+ +F LL+ LG G G V+L G G+ +AMKV+ KA++ + K + TE Sbjct: 44 VGIENFELLKVLGTGAYGKVFLVRKISGHDTGKL--YAMKVLKKATIVQKAKTTEHTRTE 101 Query: 314 REILQ-LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R++L+ PFL TL+ F+T+ L++++ GG Sbjct: 102 RQVLEHTRQSPFLVTLHYAFQTETKLHLILDYINGG 137
>CBK1_CANGA (Q6FP74) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 773 Score = 53.1 bits (126), Expect = 2e-07 Identities = 29/94 (30%), Positives = 51/94 (54%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF ++ +G G G V L + G +AMK + K+ + + +L+ + ER Sbjct: 365 LSLEDFHTVQVIGKGAFGEVRLVQKKDTGKI-----YAMKTLLKSEMYKKDQLAHVKAER 419 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++L D P++ +LY F+ ++ L+MEF PGG Sbjct: 420 DVLAGTDSPWIVSLYYSFQDAQYLYLIMEFLPGG 453
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 53.1 bits (126), Expect = 2e-07 Identities = 28/92 (30%), Positives = 48/92 (52%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 + DF ++ LG G G V L + + G ++AMK++DK + +++ E+ I Sbjct: 78 LDDFDRIKTLGTGSFGRVMLVKHKQSGN-----YYAMKILDKQKVVKLKQVEHTLNEKRI 132 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ +D PFL + F+ + +V+EF GG Sbjct: 133 LQAIDFPFLVNMTFSFKDNSNLYMVLEFISGG 164
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 52.8 bits (125), Expect = 3e-07 Identities = 30/92 (32%), Positives = 46/92 (50%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M DF L+ LG G G V L + + +A+K++ K + +R +++ TE + Sbjct: 190 MEDFDFLKVLGKGTFGKVILCKEKR-----TQKLYAIKILKKDVIIAREEVAHTLTENRV 244 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ HPFL L F+ + C VM+F GG Sbjct: 245 LQRCKHPFLTELKYSFQEQHYLCFVMQFANGG 276
>CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 719 Score = 52.8 bits (125), Expect = 3e-07 Identities = 29/94 (30%), Positives = 51/94 (54%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF ++ +G G G V L + G +AMK + K+ + + +L+ + ER Sbjct: 305 LSLEDFHTVKVIGKGAFGEVRLVQKKDTGKI-----YAMKTLLKSEMYKKDQLAHVKAER 359 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++L D P++ +LY F+ ++ L+MEF PGG Sbjct: 360 DVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGG 393
>KS6B1_RAT (P67999) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 52.8 bits (125), Expect = 3e-07 Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK-LSRAETEREILQ 328 F LLR LG G G V+ ++ K GA FAMKV+ KA + K + + ER IL+ Sbjct: 91 FELLRVLGKGGYGKVF--QVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILE 148 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + HPF+ L F+T L++E+ GG Sbjct: 149 EVKHPFIVDLIYAFQTGGKLYLILEYLSGG 178
>KS6B1_RABIT (P67998) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 52.8 bits (125), Expect = 3e-07 Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK-LSRAETEREILQ 328 F LLR LG G G V+ ++ K GA FAMKV+ KA + K + + ER IL+ Sbjct: 91 FELLRVLGKGGYGKVF--QVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILE 148 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + HPF+ L F+T L++E+ GG Sbjct: 149 EVKHPFIVDLIYAFQTGGKLYLILEYLSGG 178
>KS6B1_MOUSE (Q8BSK8) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 52.8 bits (125), Expect = 3e-07 Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK-LSRAETEREILQ 328 F LLR LG G G V+ ++ K GA FAMKV+ KA + K + + ER IL+ Sbjct: 91 FELLRVLGKGGYGKVF--QVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILE 148 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + HPF+ L F+T L++E+ GG Sbjct: 149 EVKHPFIVDLIYAFQTGGKLYLILEYLSGG 178
>KS6B1_HUMAN (P23443) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (p70-alpha) Length = 525 Score = 52.8 bits (125), Expect = 3e-07 Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK-LSRAETEREILQ 328 F LLR LG G G V+ ++ K GA FAMKV+ KA + K + + ER IL+ Sbjct: 91 FELLRVLGKGGYGKVF--QVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILE 148 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + HPF+ L F+T L++E+ GG Sbjct: 149 EVKHPFIVDLIYAFQTGGKLYLILEYLSGG 178
>CBK1_YEAST (P53894) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1) (Cell| wall biosynthesis kinase) Length = 756 Score = 52.8 bits (125), Expect = 3e-07 Identities = 29/94 (30%), Positives = 51/94 (54%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF ++ +G G G V L + G +AMK + K+ + + +L+ + ER Sbjct: 347 LSLEDFHTVKVIGKGAFGEVRLVQKKDTGKI-----YAMKTLLKSEMYKKDQLAHVKAER 401 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++L D P++ +LY F+ ++ L+MEF PGG Sbjct: 402 DVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGG 435
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 52.4 bits (124), Expect = 4e-07 Identities = 29/93 (31%), Positives = 47/93 (50%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G+ DF + LG G G V L + ++AMK++DK + +++ E+ Sbjct: 39 GLEDFERKKTLGTGSFGRVMLVKHK-----ATEQYYAMKILDKQKVVKLKQIEHTLNEKR 93 Query: 320 ILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ILQ ++ PFL L F+ + +VME+ PGG Sbjct: 94 ILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGG 126
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 52.4 bits (124), Expect = 4e-07 Identities = 29/93 (31%), Positives = 47/93 (50%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G+ DF + LG G G V L + ++AMK++DK + +++ E+ Sbjct: 39 GLEDFERKKTLGTGSFGRVMLVKHK-----ATEQYYAMKILDKQKVVKLKQIEHTLNEKR 93 Query: 320 ILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ILQ ++ PFL L F+ + +VME+ PGG Sbjct: 94 ILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGG 126
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 52.4 bits (124), Expect = 4e-07 Identities = 29/93 (31%), Positives = 47/93 (50%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G+ DF + LG G G V L + ++AMK++DK + +++ E+ Sbjct: 39 GLEDFERKKTLGTGSFGRVMLVKHK-----ATEQYYAMKILDKQKVVKLKQIEHTLNEKR 93 Query: 320 ILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ILQ ++ PFL L F+ + +VME+ PGG Sbjct: 94 ILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGG 126
>MAST3_HUMAN (O60307) Microtubule-associated serine/threonine-protein kinase 3| (EC 2.7.11.1) Length = 1309 Score = 52.4 bits (124), Expect = 4e-07 Identities = 28/90 (31%), Positives = 48/90 (53%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF ++ + G G VYL FA+K ++K +L R ++ + ER+IL Sbjct: 366 DFETIKLISNGAYGAVYLVR-----HRDTRQRFAIKKINKQNLILRNQIQQVFVERDILT 420 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++PF+ +++ FET + C+VME+ GG Sbjct: 421 FAENPFVVSMFCSFETRRHLCMVMEYVEGG 450
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 52.4 bits (124), Expect = 4e-07 Identities = 33/96 (34%), Positives = 51/96 (53%) Frame = +2 Query: 131 GPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAET 310 G +G+ DF +L+ +G G G VY ++ K + +AMKVM K + + + Sbjct: 133 GVVGIEDFEVLKVVGQGAFGKVY--QVRK---KDTSEIYAMKVMRKDKIVEKNHAEYMKA 187 Query: 311 EREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ER+IL +DHPF+ L F+T LV++F GG Sbjct: 188 ERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGG 223
>CBK1_DEBHA (Q6BLJ9) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 716 Score = 52.4 bits (124), Expect = 4e-07 Identities = 29/94 (30%), Positives = 51/94 (54%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF ++ +G G G V L + G +AMK + K+ + + +L+ + ER Sbjct: 310 LSLEDFNTVKVIGKGAFGEVRLVQKRDTGKI-----YAMKTLLKSEMYKKDQLAHVKAER 364 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++L D P++ +LY F+ ++ L+MEF PGG Sbjct: 365 DVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGG 398
>PKN2_HUMAN (Q16513) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 984 Score = 52.0 bits (123), Expect = 6e-07 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 3/93 (3%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DFR LG G G V L+E FA+K + K + +R ++ E+ I + Sbjct: 656 DFRCCAVLGRGHFGKVLLAEYKNTN-----EMFAIKALKKGDIVARDEVDSLMCEKRIFE 710 Query: 329 LLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ HPFL L+A F+T + C VME+ GG Sbjct: 711 TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGG 743
>CEK1_SCHPO (P38938) Serine/threonine-protein kinase cek1 (EC 2.7.11.1)| Length = 1338 Score = 52.0 bits (123), Expect = 6e-07 Identities = 31/110 (28%), Positives = 60/110 (54%), Gaps = 1/110 (0%) Frame = +2 Query: 92 PRWKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKA 271 PR ++ A + P + D+++L+ + G G+VYL++ G +FA+K++ K+ Sbjct: 570 PRIHTIVPNSAPEHP-SINDYKILKPISKGAFGSVYLAQKRTTGD-----YFAIKILKKS 623 Query: 272 SLESRRKLSRAETEREILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ ++ ++ ER IL + PF+ LY F++ + LVME+ GG Sbjct: 624 NMIAKNQVINVRAERAILMSQGESPFVAKLYYTFQSKDYLYLVMEYLNGG 673
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 52.0 bits (123), Expect = 6e-07 Identities = 29/93 (31%), Positives = 47/93 (50%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G+ DF + LG G G V L + ++AMK++DK + +++ E+ Sbjct: 39 GLEDFERKKTLGTGSFGRVMLVKHK-----ATEQYYAMKILDKQKVVKLKQIEHTLNEKR 93 Query: 320 ILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ILQ ++ PFL L F+ + +VME+ PGG Sbjct: 94 ILQAVNFPFLVRLEFSFKDNSNLYMVMEYVPGG 126
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 52.0 bits (123), Expect = 6e-07 Identities = 29/92 (31%), Positives = 47/92 (51%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 + F ++ LG G G V L + + G FAMK++DK + +++ E+ I Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNH-----FAMKILDKQKVVKLKQIEHTLNEKRI 94 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ ++ PFL L F+ + +VME+ PGG Sbjct: 95 LQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGG 126
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 52.0 bits (123), Expect = 6e-07 Identities = 29/92 (31%), Positives = 47/92 (51%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 + F ++ LG G G V L + + G FAMK++DK + +++ E+ I Sbjct: 39 LDQFERIKTLGTGSFGRVMLVKHKETGNH-----FAMKILDKQKVVKLKQIEHTLNEKRI 93 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ ++ PFL L F+ + +VME+ PGG Sbjct: 94 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGG 125
>PSK1_SCHPO (Q12706) Serine/threonine-protein kinase psk1 (EC 2.7.11.22)| Length = 436 Score = 52.0 bits (123), Expect = 6e-07 Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 1/97 (1%) Frame = +2 Query: 131 GPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK-LSRAE 307 G + DF+ L LG G G V L + G FA K + KAS+ R K L + + Sbjct: 84 GKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRL-----FAQKQLKKASIVLRAKGLEQTK 138 Query: 308 TEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ER+IL+ + HPF+ LY F+ L++++ PGG Sbjct: 139 NERQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGG 175
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 52.0 bits (123), Expect = 6e-07 Identities = 31/96 (32%), Positives = 49/96 (51%) Frame = +2 Query: 131 GPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAET 310 G +G+ DF +++ +G G G VY + + +AMKVM K + + + Sbjct: 127 GVVGIDDFEVMKVVGKGAFGKVYQVRKKE-----TSEIYAMKVMRKDHIMEKNHAEYMKA 181 Query: 311 EREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ER+IL +DHPF+ L F+T LV++F GG Sbjct: 182 ERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGG 217
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 51.6 bits (122), Expect = 7e-07 Identities = 29/94 (30%), Positives = 46/94 (48%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 +G+ DF LL +G G G V G +AMKV+ K + ++ +ER Sbjct: 115 VGVADFELLNLVGKGSFGKVIQVRKKDTGEV-----YAMKVLSKKHIVEHNEVEHTLSER 169 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ILQ ++HPFL L F+T+ ++++ GG Sbjct: 170 NILQKINHPFLVNLNYSFQTEDKLYFILDYVNGG 203
>PKN2_RAT (O08874) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) (Protease-activated kinase 2) (PAK-2) (Fragment) Length = 842 Score = 51.6 bits (122), Expect = 7e-07 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 3/93 (3%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DFR LG G G V L+E FA+K + K + +R ++ E+ I + Sbjct: 520 DFRCCAVLGRGHFGKVLLAEYKHTN-----EMFAIKALKKGDIVARDEVDSLMCEKRIFE 574 Query: 329 LLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ HPFL L+A F+T + C VME+ GG Sbjct: 575 TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGG 607
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 51.6 bits (122), Expect = 7e-07 Identities = 29/93 (31%), Positives = 47/93 (50%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G+ DF + LG G G V L + ++AMK++DK + +++ E+ Sbjct: 39 GLEDFERKKTLGTGSFGRVMLVKHK-----ATEQYYAMKILDKQKVVKLKQIEHTLNEKR 93 Query: 320 ILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ILQ ++ PFL L F+ + +VME+ PGG Sbjct: 94 ILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGG 126
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 51.6 bits (122), Expect = 7e-07 Identities = 29/93 (31%), Positives = 47/93 (50%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G+ DF + LG G G V L + ++AMK++DK + +++ E+ Sbjct: 39 GLEDFERKKTLGTGSFGRVMLVKHK-----ATEQYYAMKILDKQKVVKLKQIEHTLNEKR 93 Query: 320 ILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ILQ ++ PFL L F+ + +VME+ PGG Sbjct: 94 ILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGG 126
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 51.6 bits (122), Expect = 7e-07 Identities = 32/89 (35%), Positives = 52/89 (58%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F LL+ LG G G V+L + +AMKV+ KA+L+ R ++ R + ER+IL Sbjct: 80 FELLKVLGQGSFGKVFLVRKITPPDSNHL--YAMKVLKKATLKVRDRV-RTKIERDILAD 136 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++HPF+ L+ F+T+ L+++F GG Sbjct: 137 VNHPFVVKLHYAFQTEGKLYLILDFLRGG 165
>PKN2_MOUSE (Q8BWW9) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 983 Score = 51.6 bits (122), Expect = 7e-07 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 3/93 (3%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DFR LG G G V L+E FA+K + K + +R ++ E+ I + Sbjct: 655 DFRCCAVLGRGHFGKVLLAEYKHTN-----EMFAIKALKKGDIVARDEVDSLMCEKRIFE 709 Query: 329 LLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ HPFL L+A F+T + C VME+ GG Sbjct: 710 TVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGG 742
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 51.6 bits (122), Expect = 7e-07 Identities = 29/93 (31%), Positives = 47/93 (50%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G+ DF + LG G G V L + ++AMK++DK + +++ E+ Sbjct: 86 GLEDFERKKTLGTGSFGRVMLVKHK-----ATEQYYAMKILDKQKVVKLKQIEHTLNEKR 140 Query: 320 ILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ILQ ++ PFL L F+ + +VME+ PGG Sbjct: 141 ILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGG 173
>RIM15_YEAST (P43565) Serine/threonine-protein kinase RIM15 (EC 2.7.11.1)| Length = 1770 Score = 51.2 bits (121), Expect = 9e-07 Identities = 28/91 (30%), Positives = 53/91 (58%), Gaps = 1/91 (1%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 D+ +L+ + G G+VYL+ G +FA+KV+ K+ + ++ +++ ++ER I+ Sbjct: 793 DYDILKPISKGAYGSVYLARKKLTGD-----YFAIKVLRKSDMIAKNQVTNVKSERAIMM 847 Query: 329 LL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 + D P++ L+A F+ LVME+ PGG Sbjct: 848 VQSDKPYVARLFASFQNKDNLFLVMEYLPGG 878
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 51.2 bits (121), Expect = 9e-07 Identities = 28/92 (30%), Positives = 48/92 (52%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 + F ++ LG G G V L + ++ G +AMK++DK + +++ E+ I Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHTETGNH-----YAMKILDKQKVVKLKQIEHTLNEKRI 94 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ ++ PFL L F+ + +VME+ PGG Sbjct: 95 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGG 126
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 51.2 bits (121), Expect = 9e-07 Identities = 33/89 (37%), Positives = 52/89 (58%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F LL+ LG G G V+L A + +AMKV+ KA+L+ R ++ R + ER+IL Sbjct: 62 FVLLKVLGQGSFGKVFLVRKITPPDANQL--YAMKVLKKATLKVRDRV-RTKMERDILAD 118 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + HPF+ L+ F+T+ L+++F GG Sbjct: 119 VHHPFVVRLHYAFQTEGKLYLILDFLRGG 147
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 50.8 bits (120), Expect = 1e-06 Identities = 28/92 (30%), Positives = 47/92 (51%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 + F ++ LG G G V L + + G +AMK++DK + +++ E+ I Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHKETGNH-----YAMKILDKQKVVKLKQIEHTLNEKRI 94 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ ++ PFL L F+ + +VME+ PGG Sbjct: 95 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGG 126
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 50.8 bits (120), Expect = 1e-06 Identities = 30/89 (33%), Positives = 45/89 (50%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F L+ LG G G V L + G +AMK++DK + +++ E+ ILQ Sbjct: 42 FERLKTLGTGSYGRVMLVRHRETGNH-----YAMKILDKQKVVRLKQVEHTLNEKRILQA 96 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ PFL L F+ + LVME+ PGG Sbjct: 97 INFPFLVKLQFSFKDNSNLYLVMEYVPGG 125
>ORB6_SCHPO (O13310) Serine/threonine-protein kinase orb6 (EC 2.7.11.1)| Length = 469 Score = 50.4 bits (119), Expect = 2e-06 Identities = 30/94 (31%), Positives = 49/94 (52%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF ++ +G G G V L + G +AMK + K + R +L+ + ER Sbjct: 88 LSLEDFSTIKVIGKGAFGEVRLVQKLDTGKI-----YAMKSLLKTEMFKRDQLAHVKAER 142 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++L D P++ +LY F+ + L+MEF PGG Sbjct: 143 DLLVESDSPWVVSLYYAFQDSLYLYLIMEFLPGG 176
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 50.4 bits (119), Expect = 2e-06 Identities = 28/89 (31%), Positives = 46/89 (51%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F ++ LG G G V L + + G +AMK++DK + +++ E+ ILQ Sbjct: 43 FDRIKTLGTGSFGRVMLVKHKESGNH-----YAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ PFL L F+ + +VME+ PGG Sbjct: 98 VNFPFLVKLEFSFKDNSNLYMVMEYVPGG 126
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 50.4 bits (119), Expect = 2e-06 Identities = 28/92 (30%), Positives = 47/92 (51%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 + F ++ LG G G V L + + G +AMK++DK + +++ E+ I Sbjct: 40 LDQFERIKTLGTGSFGRVMLVKHMETGNH-----YAMKILDKQKVVKLKQIEHTLNEKRI 94 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ ++ PFL L F+ + +VME+ PGG Sbjct: 95 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGG 126
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 50.1 bits (118), Expect = 2e-06 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ +F ++ LG G G V L+EL G+ +A+KV+ K + + TE+ Sbjct: 403 LGLDEFNFIKVLGKGSFGKVMLAELK-----GKDEVYAVKVLKKDVILQDDDVDCTMTEK 457 Query: 317 EILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 IL L HP+L LY F+T VME+ GG Sbjct: 458 RILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGG 492
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 50.1 bits (118), Expect = 2e-06 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ +F ++ LG G G V L+EL G+ +A+KV+ K + + TE+ Sbjct: 403 LGLDEFNFIKVLGKGSFGKVMLAELK-----GKDEVYAVKVLKKDVILQDDDVDCTMTEK 457 Query: 317 EILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 IL L HP+L LY F+T VME+ GG Sbjct: 458 RILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGG 492
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 50.1 bits (118), Expect = 2e-06 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ +F ++ LG G G V L+EL G+ +A+KV+ K + + TE+ Sbjct: 403 LGLDEFNFIKVLGKGSFGKVMLAELK-----GKDEVYAVKVLKKDVILQDDDVDCTMTEK 457 Query: 317 EILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 IL L HP+L LY F+T VME+ GG Sbjct: 458 RILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGG 492
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 50.1 bits (118), Expect = 2e-06 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ +F ++ LG G G V L+EL G+ +A+KV+ K + + TE+ Sbjct: 402 LGLDEFNFIKVLGKGSFGKVMLAELK-----GKDEVYAVKVLKKDVILQDDDVDCTMTEK 456 Query: 317 EILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 IL L HP+L LY F+T VME+ GG Sbjct: 457 RILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGG 491
>PCK1_SCHPO (P36582) Protein kinase C-like 1 (EC 2.7.11.13)| Length = 988 Score = 50.1 bits (118), Expect = 2e-06 Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 3/95 (3%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 + DF L LG G+ G V L+E ++A+KV+ K ++ +L +TE+ + Sbjct: 661 LDDFTFLAVLGKGNFGKVMLAEYKVN-----KKFYAIKVLKKEAILKNEELESLKTEKHV 715 Query: 323 LQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ + HPFL L+A F+T VME+ GG Sbjct: 716 FEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGG 750
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 50.1 bits (118), Expect = 2e-06 Identities = 29/92 (31%), Positives = 46/92 (50%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M +F ++ LG G G V L + A ++AMK++ K + ++ +++ TE + Sbjct: 147 MNEFEYVKLLGKGTFGKVILVKEK-----ATAAYYAMKILKKEVIVAKDEVAHTLTENRV 201 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ HP L L F+T C VME+ GG Sbjct: 202 LQNSRHPSLTALKYSFQTHDRLCFVMEYANGG 233
>DMPK_MOUSE (P54265) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 631 Score = 50.1 bits (118), Expect = 2e-06 Identities = 31/108 (28%), Positives = 56/108 (51%) Frame = +2 Query: 95 RWKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKAS 274 +W +AAR + L DF +L+ +G G V + ++ + G +AMK+M+K Sbjct: 52 QWVEPIAARLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQV-----YAMKIMNKWD 106 Query: 275 LESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + R ++S ER++L D ++ L+ F+ + + LVME+ GG Sbjct: 107 MLKRGEVSCFREERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGG 154
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 49.7 bits (117), Expect = 3e-06 Identities = 33/102 (32%), Positives = 54/102 (52%) Frame = +2 Query: 113 AARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK 292 +A + D +G++RLL+ +G G+ V L+ G A+K++DK L S Sbjct: 40 SATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKE-----VAVKIIDKTQLNSS-S 93 Query: 293 LSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L + E I+++L+HP + L+ ET+K LVME+ GG Sbjct: 94 LQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGG 135
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 49.7 bits (117), Expect = 3e-06 Identities = 28/89 (31%), Positives = 46/89 (51%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F ++ LG G G V L + + G +AMK++DK + +++ E+ ILQ Sbjct: 43 FDRIKTLGTGSFGRVMLVKHKETGNH-----YAMKILDKQKVVKLKQIEHTLNEKRILQA 97 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ PFL L F+ + +VME+ PGG Sbjct: 98 VNFPFLVKLEFSFKDNSNLYMVMEYVPGG 126
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 49.7 bits (117), Expect = 3e-06 Identities = 33/102 (32%), Positives = 54/102 (52%) Frame = +2 Query: 113 AARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK 292 +A + D +G++RLL+ +G G+ V L+ G A+K++DK L S Sbjct: 40 SATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKE-----VAVKIIDKTQLNSS-S 93 Query: 293 LSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L + E I+++L+HP + L+ ET+K LVME+ GG Sbjct: 94 LQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGG 135
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 49.7 bits (117), Expect = 3e-06 Identities = 33/102 (32%), Positives = 54/102 (52%) Frame = +2 Query: 113 AARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK 292 +A + D +G++RLL+ +G G+ V L+ G A+K++DK L S Sbjct: 40 SATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKE-----VAVKIIDKTQLNSS-S 93 Query: 293 LSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L + E I+++L+HP + L+ ET+K LVME+ GG Sbjct: 94 LQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGG 135
>ST38L_HUMAN (Q9Y2H1) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 49.3 bits (116), Expect = 4e-06 Identities = 28/94 (29%), Positives = 49/94 (52%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF L+ +G G G V L + G +AMK++ K+ + + +++ ER Sbjct: 85 LGLDDFESLKVIGRGAFGEVRLVQKKDTGHI-----YAMKILRKSDMLEKEQVAHIRAER 139 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +IL D ++ ++ F+ + L+MEF PGG Sbjct: 140 DILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGG 173
>CTRO_HUMAN (O14578) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2027 Score = 49.3 bits (116), Expect = 4e-06 Identities = 31/90 (34%), Positives = 44/90 (48%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF + +GCG V + G +AMKVM K +L ++ ++S E ER IL Sbjct: 96 DFEVRSLVGCGHFAEVQVVREKATGDI-----YAMKVMKKKALLAQEQVSFFEEERNILS 150 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 P++P L F+ LVME+ PGG Sbjct: 151 RSTSPWIPQLQYAFQDKNHLYLVMEYQPGG 180
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 49.3 bits (116), Expect = 4e-06 Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 4/102 (3%) Frame = +2 Query: 125 GDGPL---GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKL 295 GDGP+ + F LL+ LG G G V L EL G+ ++AMK + K + Sbjct: 363 GDGPVKKFALPHFNLLKVLGKGSFGKVMLVELK-----GKNEFYAMKCLKKDVILEDDDT 417 Query: 296 SRAETEREILQLLDH-PFLPTLYAHFETDKFACLVMEFCPGG 418 ER +L L PFL L+ F+T+++ VME+ GG Sbjct: 418 ECTYIERRVLILASQCPFLCQLFCSFQTNEYLFFVMEYLNGG 459
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 48.9 bits (115), Expect = 5e-06 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ +F +R LG G G V L+ + + G +A+KV+ K + + TE+ Sbjct: 349 LGIDNFEFIRVLGKGSFGKVMLARVKETGDL-----YAVKVLKKDVILLDDDVECTMTEK 403 Query: 317 EILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 IL L +HPFL L+ F+T VMEF GG Sbjct: 404 RILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGG 438
>KPCI_PONPY (Q5R4K9) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| Length = 587 Score = 48.9 bits (115), Expect = 5e-06 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF LLR +G G V L L K +AMKV+ K + + +TE+ Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKTDRI-----YAMKVVKKELVNDDEDIDWVQTEK 294 Query: 317 EIL-QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + Q +HPFL L++ F+T+ V+E+ GG Sbjct: 295 HVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGG 329
>KPCI_HUMAN (P41743) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota) Length = 587 Score = 48.9 bits (115), Expect = 5e-06 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF LLR +G G V L L K +AMKV+ K + + +TE+ Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKTDRI-----YAMKVVKKELVNDDEDIDWVQTEK 294 Query: 317 EIL-QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + Q +HPFL L++ F+T+ V+E+ GG Sbjct: 295 HVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGG 329
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 48.9 bits (115), Expect = 5e-06 Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 1/103 (0%) Frame = +2 Query: 113 AARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK 292 + G +G F LLR LG G G V+ +G G+ +AMKV+ KA + K Sbjct: 54 SVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKI--YAMKVLRKAKIVRNAK 111 Query: 293 -LSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + ER IL+ + HPF+ L F+T L++E GG Sbjct: 112 DTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGG 154
>KPCZ_RABIT (O19111) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 591 Score = 48.9 bits (115), Expect = 5e-06 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF L+R +G G V L L K G +AMKV+ K + + +TE+ Sbjct: 246 LGLQDFDLIRVIGRGSYAKVLLVRLKKNGQV-----YAMKVVKKELVHDDEDIDWVQTEK 300 Query: 317 EIL-QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + Q +PFL L++ F+T LV+E+ GG Sbjct: 301 HVFEQASGNPFLVGLHSCFQTTSRLFLVIEYVNGG 335
>KPCI_MOUSE (Q62074) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) Length = 586 Score = 48.9 bits (115), Expect = 5e-06 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF LLR +G G V L L K +AMKV+ K + + +TE+ Sbjct: 239 LGLQDFDLLRVIGRGSYAKVLLVRLKKTDRI-----YAMKVVKKELVNDDEDIDWVQTEK 293 Query: 317 EIL-QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + Q +HPFL L++ F+T+ V+E+ GG Sbjct: 294 HVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGG 328
>CTRO_MOUSE (P49025) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2055 Score = 48.5 bits (114), Expect = 6e-06 Identities = 30/90 (33%), Positives = 44/90 (48%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF + +GCG V + G +AMK+M K +L ++ ++S E ER IL Sbjct: 96 DFEVRSLVGCGHFAEVQVVREKATGDV-----YAMKIMKKKALLAQEQVSFFEEERNILS 150 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 P++P L F+ LVME+ PGG Sbjct: 151 RSTSPWIPQLQYAFQDKNNLYLVMEYQPGG 180
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 48.5 bits (114), Expect = 6e-06 Identities = 30/92 (32%), Positives = 41/92 (44%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 M DF L+ LG G G V L +A+K++ K + R +++ TE + Sbjct: 177 MDDFDFLKVLGQGTFGKVILCREKSSDKL-----YAIKIIRKEMVVDRSEVAHTLTENRV 231 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L HPFL L F+ C VMEF GG Sbjct: 232 LYACVHPFLTLLKYSFQAQYHICFVMEFANGG 263
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 48.1 bits (113), Expect = 8e-06 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G+ +F +R LG G G V L+ + + G +A+KV+ K + + TE+ Sbjct: 351 GIDNFEFIRVLGKGSFGKVMLARIKETGEL-----YAVKVLKKDVILQDDDVECTMTEKR 405 Query: 320 ILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 IL L +HPFL L+ F+T VMEF GG Sbjct: 406 ILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGG 439
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 48.1 bits (113), Expect = 8e-06 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G+ +F +R LG G G V L+ + + G +A+KV+ K + + TE+ Sbjct: 351 GIDNFEFIRVLGKGSFGKVMLARIKETGEL-----YAVKVLKKDVILQDDDVECTMTEKR 405 Query: 320 ILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 IL L +HPFL L+ F+T VMEF GG Sbjct: 406 ILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGG 439
>STK38_MOUSE (Q91VJ4) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 48.1 bits (113), Expect = 8e-06 Identities = 29/94 (30%), Positives = 47/94 (50%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF L+ +G G G V L + G +AMK++ KA + + ++ ER Sbjct: 84 LGLEDFESLKVIGRGAFGEVRLVQKKDTGHV-----YAMKILRKADMLEKEQVGHIRAER 138 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +IL D ++ ++ F+ L+MEF PGG Sbjct: 139 DILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGG 172
>STK38_HUMAN (Q15208) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 48.1 bits (113), Expect = 8e-06 Identities = 29/94 (30%), Positives = 47/94 (50%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF L+ +G G G V L + G +AMK++ KA + + ++ ER Sbjct: 84 LGLEDFESLKVIGRGAFGEVRLVQKKDTGHV-----YAMKILRKADMLEKEQVGHIRAER 138 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +IL D ++ ++ F+ L+MEF PGG Sbjct: 139 DILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGG 172
>ST38L_MOUSE (Q7TSE6) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 48.1 bits (113), Expect = 8e-06 Identities = 28/94 (29%), Positives = 48/94 (51%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF L+ + G G V L + G +AMK++ KA + + +++ ER Sbjct: 85 LGLDDFESLKVIARGAFGEVRLVQKKDTGHI-----YAMKILRKADMLEKEQVAHIRAER 139 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +IL D ++ ++ F+ + L+MEF PGG Sbjct: 140 DILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGG 173
>COT1_NEUCR (P38679) Serine/threonine-protein kinase cot-1 (EC 2.7.11.1)| (Colonial temperature-sensitive 1) Length = 598 Score = 47.8 bits (112), Expect = 1e-05 Identities = 27/90 (30%), Positives = 46/90 (51%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 +++ ++ +G G G V L + G +AMK + K + + +L+ ER+IL Sbjct: 213 NYQTIKIIGKGAFGEVKLVQKKADGKV-----YAMKSLIKTEMFKKDQLAHVRAERDILA 267 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 D P++ LY F+ F ++MEF PGG Sbjct: 268 ESDSPWVVKLYTTFQDANFLYMLMEFLPGG 297
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 47.8 bits (112), Expect = 1e-05 Identities = 27/92 (29%), Positives = 46/92 (50%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 + F ++ LG G G V L + + G +AMK++DK + +++ E+ I Sbjct: 40 LDQFDRIKTLGTGSFGRVMLVKHKESGNH-----YAMKILDKQKVVKLKQIEHTLNEKRI 94 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LQ ++ PFL L F+ + +VME+ GG Sbjct: 95 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGG 126
>GRK1_CAEEL (Q09537) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 642 Score = 47.8 bits (112), Expect = 1e-05 Identities = 29/95 (30%), Positives = 48/95 (50%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FRL R LG G G V ++ G +A+K ++K ++ R + + E Sbjct: 197 PVDKHTFRLYRVLGKGGFGEVCACQVRASG-----KMYALKKLEKKRVKKRHAETLSLNE 251 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ILQ ++ PF+ +L +ET CLV+ GG Sbjct: 252 KQILQRINSPFVVSLAYAYETKDALCLVLTLMNGG 286
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 47.8 bits (112), Expect = 1e-05 Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 3/97 (3%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 +G+ DF L LG G+ G V L+EL +A+KV+ K + ++ ++E+ Sbjct: 678 IGLEDFTFLSVLGKGNFGKVMLAELKS-----EKQLYAIKVLKKEFILENDEVESTKSEK 732 Query: 317 EILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 + + + HPFL L++ F+T+ VM+F GG Sbjct: 733 RVFLVANRERHPFLVNLHSCFQTETRIYFVMDFVSGG 769
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 47.8 bits (112), Expect = 1e-05 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF LLR +G G V L L K +AMKV+ K + + +TE+ Sbjct: 241 LGLIDFDLLRVIGRGSYAKVLLVRLKKTERI-----YAMKVVKKELVNDDEDIDWVQTEK 295 Query: 317 EIL-QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + Q +HPFL L++ F+T+ V+E+ GG Sbjct: 296 HVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGG 330
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 47.4 bits (111), Expect = 1e-05 Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 2/103 (1%) Frame = +2 Query: 116 ARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLE--SRR 289 A D +G++RLL+ +G G+ V L+ G A+K++DK L S + Sbjct: 44 ASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGRE-----VAIKIIDKTQLNPTSLQ 98 Query: 290 KLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 KL R E I+++L+HP + L+ ET+K L+ME+ GG Sbjct: 99 KLFR---EVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGG 138
>GRK1_CAEBR (Q622Z7) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 640 Score = 47.4 bits (111), Expect = 1e-05 Identities = 29/95 (30%), Positives = 48/95 (50%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FRL R LG G G V ++ G +A+K ++K ++ R + + E Sbjct: 196 PVDKHTFRLYRVLGKGGFGEVCACQVRASG-----KMYALKKLEKKRVKKRHAETLSLNE 250 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ILQ ++ PF+ +L +ET CLV+ GG Sbjct: 251 KQILQKVNSPFVVSLAYAYETKDALCLVLTLMNGG 285
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 47.4 bits (111), Expect = 1e-05 Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 2/103 (1%) Frame = +2 Query: 116 ARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLE--SRR 289 A D +G++RLL+ +G G+ V L+ G A+K++DK L S + Sbjct: 44 ASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGRE-----VAIKIIDKTQLNPTSLQ 98 Query: 290 KLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 KL R E I+++L+HP + L+ ET+K L+ME+ GG Sbjct: 99 KLFR---EVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGG 138
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 47.4 bits (111), Expect = 1e-05 Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 2/103 (1%) Frame = +2 Query: 116 ARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLE--SRR 289 A D +G++RLL+ +G G+ V L+ G A+K++DK L S + Sbjct: 44 ASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGRE-----VAIKIIDKTQLNPTSLQ 98 Query: 290 KLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 KL R E I+++L+HP + L+ ET+K L+ME+ GG Sbjct: 99 KLFR---EVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGG 138
>KPC1_TRIRE (Q99014) Protein kinase C-like (EC 2.7.11.13)| Length = 1139 Score = 47.4 bits (111), Expect = 1e-05 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 3/97 (3%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 +G+ F L LG G+ G V L+E + FA+KV+ K + ++ ++E+ Sbjct: 809 IGLDHFNFLAVLGKGNFGKVMLAETKRSKRL-----FAIKVLKKEFIIENDEVESIKSEK 863 Query: 317 EILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 + + + HPFL L+A F+T+ VME+ GG Sbjct: 864 RVFLIANRERHPFLTNLHACFQTETRVYFVMEYISGG 900
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 47.4 bits (111), Expect = 1e-05 Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 1/103 (0%) Frame = +2 Query: 113 AARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK 292 A++ G L + DF ++ LG G G V L+E G +A+K++ K + Sbjct: 365 ASKVPGGTLSIHDFTFMKVLGKGSFGKVMLAERK-----GTDEVYAIKILKKDVIVQDDD 419 Query: 293 LSRAETEREILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 + E+ IL L HPFL L++ F+T VME+ GG Sbjct: 420 VECTMCEKRILSLAAKHPFLTALHSSFQTSDRLFFVMEYVNGG 462
>KPC1_NEUCR (P87253) Protein kinase C-like (EC 2.7.11.13)| Length = 1142 Score = 47.4 bits (111), Expect = 1e-05 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 3/97 (3%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 +G+ F L LG G+ G V L+E K +A+KV+ K + ++ +E+ Sbjct: 812 IGLDHFNFLAVLGKGNFGKVMLAETKKS-----RKLYAIKVLKKEFIIENDEVESIRSEK 866 Query: 317 EILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 + + + HPFL L+A F+T+ VME+ GG Sbjct: 867 RVFLIANRERHPFLTNLHACFQTETRVYFVMEYISGG 903
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 47.0 bits (110), Expect = 2e-05 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = +2 Query: 116 ARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKL 295 +R+ + + DF ++ LG G G V L+E G +A+KV+ K + + Sbjct: 391 SRSHHSRISLHDFNFIKVLGKGSFGKVMLAEKK-----GTDEVYAIKVLKKDVIIQDDDV 445 Query: 296 SRAETEREILQL-LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 TE+ IL L HPFL L++ F+T + VME+ GG Sbjct: 446 ECTMTEKRILALSAKHPFLTALHSSFQTKERLFFVMEYVNGG 487
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 47.0 bits (110), Expect = 2e-05 Identities = 27/90 (30%), Positives = 46/90 (51%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 +F L+ LG G G V L A +A+K++ K + + +++ TE +L+ Sbjct: 265 NFEFLKVLGKGTFGKVILCREK-----ATAKLYAIKILKKEVIIQKDEVAHTLTESRVLK 319 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +HPFL +L F+T+ C VM++ GG Sbjct: 320 STNHPFLISLKYSFQTNDRLCFVMQYVNGG 349
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 47.0 bits (110), Expect = 2e-05 Identities = 31/94 (32%), Positives = 45/94 (47%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF + R+LG G G VY K G A+K ++K + L + + E Sbjct: 95 LSLKDFEVGRKLGKGKFGKVYCVRHKKSGFI-----CALKAIEKNEILQFNLLKQLKREV 149 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +I +DHP + LYAHF +K L+ME G Sbjct: 150 DIQLGMDHPNIIKLYAHFHDEKRVYLLMEHSING 183
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 46.6 bits (109), Expect = 2e-05 Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 1/99 (1%) Frame = +2 Query: 125 GDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLE-SRRKLSR 301 G +G F LL LG G G V+ +G G+ +AMKV+ KA + S + + Sbjct: 58 GPERIGPHCFELLSVLGKGGYGKVFQVRKVQGTNLGKI--YAMKVLRKAKIVCSAKDTAH 115 Query: 302 AETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ER IL+ + HPF+ L F+T L++E GG Sbjct: 116 TRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGG 154
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 46.6 bits (109), Expect = 2e-05 Identities = 32/97 (32%), Positives = 48/97 (49%), Gaps = 1/97 (1%) Frame = +2 Query: 131 GPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAET 310 G + DF ++ LG G G V L+E G +A+KV+ K ++ + T Sbjct: 296 GKCSLLDFNFIKVLGKGSFGKVMLAEKK-----GTDEIYAIKVLKKDAIIQDDDVDCTMT 350 Query: 311 EREILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 E+ IL L +HPFL L++ F+T VME+ GG Sbjct: 351 EKRILALAANHPFLTALHSCFQTPDRLFFVMEYVNGG 387
>MASTL_HUMAN (Q96GX5) Microtubule-associated serine/threonine-protein| kinase-like (EC 2.7.11.1) Length = 879 Score = 46.6 bits (109), Expect = 2e-05 Identities = 29/95 (30%), Positives = 49/95 (51%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P + +F +++ + G G VYL + KGG +A+KV+ KA + ++ + + E Sbjct: 29 PPSIEEFSIVKPISRGAFGKVYLGQ--KGGKL-----YAVKVVKKADMINKNMTHQVQAE 81 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R+ L L PF+ LY ++ LVME+ GG Sbjct: 82 RDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGG 116
>KPCZ_RAT (P09217) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 46.2 bits (108), Expect = 3e-05 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF L+R +G G V L L K +AMKV+ K + + +TE+ Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKNDQI-----YAMKVVKKELVHDDEDIDWVQTEK 301 Query: 317 EIL-QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + Q +PFL L++ F+T LV+E+ GG Sbjct: 302 HVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGG 336
>KPCZ_MOUSE (Q02956) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 46.2 bits (108), Expect = 3e-05 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF L+R +G G V L L K +AMKV+ K + + +TE+ Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKNDQI-----YAMKVVKKELVHDDEDIDWVQTEK 301 Query: 317 EIL-QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + Q +PFL L++ F+T LV+E+ GG Sbjct: 302 HVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGG 336
>KPCZ_HUMAN (Q05513) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 46.2 bits (108), Expect = 3e-05 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 LG+ DF L+R +G G V L L K +AMKV+ K + + +TE+ Sbjct: 247 LGLQDFDLIRVIGRGSYAKVLLVRLKKNDQI-----YAMKVVKKELVHDDEDIDWVQTEK 301 Query: 317 EIL-QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + Q +PFL L++ F+T LV+E+ GG Sbjct: 302 HVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGG 336
>PRKY_HUMAN (O43930) Serine/threonine-protein kinase PRKY (EC 2.7.11.1)| Length = 277 Score = 46.2 bits (108), Expect = 3e-05 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Frame = +2 Query: 116 ARAGDGPL-GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRK 292 AR+ + P + D L +G G G V+L + +FA+KVM + R++ Sbjct: 36 ARSPEAPAYRLQDCDALVTMGTGTFGRVHLVKEKTA-----KHFFALKVMSIPDVIRRKQ 90 Query: 293 LSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 E+ +L+ + HPFL L+ + ++F ++ME+ PGG Sbjct: 91 EQHVHNEKSVLKEVSHPFLIRLFWTWHEERFLYMLMEYVPGG 132
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 46.2 bits (108), Expect = 3e-05 Identities = 36/111 (32%), Positives = 61/111 (54%), Gaps = 2/111 (1%) Frame = +2 Query: 92 PRWKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKA 271 PR + + + + P +G++RL + +G G+ V +L++ GR A+K++DK Sbjct: 41 PRCRNSITSATDEQP-HIGNYRLQKTIGKGNFAKV---KLARHVLTGRE--VAVKIIDKT 94 Query: 272 SLE--SRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L S +KL R E I+++L+HP + L+ ET+K LVME+ GG Sbjct: 95 QLNPTSLQKLFR---EVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGG 142
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 46.2 bits (108), Expect = 3e-05 Identities = 36/111 (32%), Positives = 61/111 (54%), Gaps = 2/111 (1%) Frame = +2 Query: 92 PRWKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKA 271 PR + + + + P +G++RL + +G G+ V +L++ GR A+K++DK Sbjct: 41 PRCRNSITSATDEQP-HIGNYRLQKTIGKGNFAKV---KLARHVLTGRE--VAVKIIDKT 94 Query: 272 SLE--SRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L S +KL R E I+++L+HP + L+ ET+K LVME+ GG Sbjct: 95 QLNPTSLQKLFR---EVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGG 142
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 46.2 bits (108), Expect = 3e-05 Identities = 28/94 (29%), Positives = 50/94 (53%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 + + D R++ LG G G V L + + G + R+ FA+K M K+ + R+ +E+ Sbjct: 618 INLTDLRVIATLGVGGFGRVELVQTN--GDSSRS--FALKQMKKSQIVETRQQQHIMSEK 673 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 EI+ + F+ L+ F+ K+ ++ME C GG Sbjct: 674 EIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGG 707
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 46.2 bits (108), Expect = 3e-05 Identities = 28/94 (29%), Positives = 50/94 (53%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 + + D R++ LG G G V L + + G + R+ FA+K M K+ + R+ +E+ Sbjct: 772 INLTDLRVIATLGVGGFGRVELVQTN--GDSSRS--FALKQMKKSQIVETRQQQHIMSEK 827 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 EI+ + F+ L+ F+ K+ ++ME C GG Sbjct: 828 EIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGG 861
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 46.2 bits (108), Expect = 3e-05 Identities = 29/95 (30%), Positives = 46/95 (48%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FR+ R LG G G V ++ G +A K ++K ++ R+ S E Sbjct: 303 PITYKTFRMYRVLGKGGFGEVCACQVRATG-----KMYACKKLEKKRIKKRKGESMVLIE 357 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ILQ ++ PF+ L +ET CLV+ GG Sbjct: 358 KQILQKINSPFVVNLAYAYETKDALCLVLTIMNGG 392
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 46.2 bits (108), Expect = 3e-05 Identities = 36/111 (32%), Positives = 61/111 (54%), Gaps = 2/111 (1%) Frame = +2 Query: 92 PRWKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKA 271 PR + + + + P +G++RL + +G G+ V +L++ GR A+K++DK Sbjct: 41 PRCRNSITSATDEQP-HIGNYRLQKTIGKGNFAKV---KLARHVLTGRE--VAVKIIDKT 94 Query: 272 SLE--SRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L S +KL R E I+++L+HP + L+ ET+K LVME+ GG Sbjct: 95 QLNPTSLQKLFR---EVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGG 142
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 46.2 bits (108), Expect = 3e-05 Identities = 26/90 (28%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF L +G G G V+L + +FA+KVM + ++ E+ +L+ Sbjct: 48 DFDTLATVGTGTFGRVHLVKEKTA-----KHFFALKVMSIPDVIRLKQEQHVHNEKSVLK 102 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + HPFL L+ + ++F ++ME+ PGG Sbjct: 103 EVSHPFLIRLFWTWHDERFLYMLMEYVPGG 132
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 45.8 bits (107), Expect = 4e-05 Identities = 31/90 (34%), Positives = 42/90 (46%) Frame = +2 Query: 146 GDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREIL 325 G FR+LR LG G +G VYL E G A+KV+ R + E +L Sbjct: 11 GRFRVLRPLGSGGMGEVYLGEQVSLGRK-----VAIKVLHHDLHAQAGMAERFKREARLL 65 Query: 326 QLLDHPFLPTLYAHFETDKFACLVMEFCPG 415 ++HP + + E+ ACLVMEF G Sbjct: 66 SAVEHPAVVRIVDFGESGDHACLVMEFVEG 95
>KPC1_YEAST (P24583) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1151 Score = 45.8 bits (107), Expect = 4e-05 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 + + +F LL+ LG G+ G V LS K R A+KV+ K ++ + A E+ Sbjct: 819 VSLDNFVLLKVLGKGNFGKVILS---KSKNTDRL--CAIKVLKKDNIIQNHDIESARAEK 873 Query: 317 EILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ L HPFL LY F+T+ MEF GG Sbjct: 874 KVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGG 910
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 45.8 bits (107), Expect = 4e-05 Identities = 30/94 (31%), Positives = 45/94 (47%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF + R LG G G VYL+ L + A+KV+ K+ +E + E Sbjct: 38 LTVDDFEIGRPLGKGKFGNVYLARLKESHFI-----VALKVLFKSQIEKEGLEHQLRREI 92 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 EI L HP + LY +F + L++E+ P G Sbjct: 93 EIQAHLQHPNILRLYNYFHDARRVYLILEYAPRG 126
>MASTL_MOUSE (Q8C0P0) Microtubule-associated serine/threonine-protein| kinase-like (EC 2.7.11.1) Length = 865 Score = 45.8 bits (107), Expect = 4e-05 Identities = 28/95 (29%), Positives = 49/95 (51%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P + +F +++ + G G VYL + KGG +A+KV+ KA + ++ + + E Sbjct: 28 PPSIEEFTIVKPISRGAFGKVYLGQ--KGGKL-----YAVKVVKKADMVNKNMTHQVQAE 80 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R+ L L PF+ LY ++ L+ME+ GG Sbjct: 81 RDALALSKSPFVVHLYYSLQSASNIYLIMEYLIGG 115
>GRK7_PIG (Q8WP15) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 45.8 bits (107), Expect = 4e-05 Identities = 28/90 (31%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 +FR+L + G G++ V + K +A K +DK L+ + A +E+EIL+ Sbjct: 193 EFRVLGKGGFGEVCAVQVKNTGK--------MYACKKLDKKRLKKKSGEKMALSEKEILE 244 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + PF+ +L FE+ CLVM GG Sbjct: 245 KVSSPFVVSLAYAFESKSHLCLVMSLMNGG 274
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 45.4 bits (106), Expect = 5e-05 Identities = 30/92 (32%), Positives = 44/92 (47%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 + DF + R LG G G VYL+ L + A+KV+ K+ +E + E EI Sbjct: 13 INDFEIGRPLGRGKFGRVYLARLKENHFI-----VALKVLFKSEIEKEGLEHQLRREVEI 67 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L H + LY +F D L++E+ PGG Sbjct: 68 QAHLQHRNILRLYNYFYDDTRIYLILEYAPGG 99
>KPC1_ASPNG (Q00078) Protein kinase C-like (EC 2.7.11.13)| Length = 1096 Score = 45.4 bits (106), Expect = 5e-05 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 3/97 (3%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 +G+ F L LG G+ G V L+E +A+KV+ K + ++ ++E+ Sbjct: 766 IGLDHFNFLAVLGKGNFGKVMLAETKS-----TKRLYAIKVLKKEFIIENDEVESTKSEK 820 Query: 317 EILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 + + + HPFL L+A F+T+ VME+ GG Sbjct: 821 RVFMIANKERHPFLLNLHACFQTETRVYFVMEYISGG 857
>KGP1_DROME (Q03042) cGMP-dependent protein kinase, isozyme 1 (EC 2.7.11.12)| (CGK) Length = 768 Score = 45.4 bits (106), Expect = 5e-05 Identities = 28/94 (29%), Positives = 44/94 (46%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + D ++ LG G G V EL K R FA+K + K + ++ +ER Sbjct: 452 LKLTDLEVVSTLGIGGFGRV---ELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSER 508 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 I+ PF+ LY F +K+ +++E C GG Sbjct: 509 HIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGG 542
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 45.1 bits (105), Expect = 7e-05 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF L + LG G G V+L+E K +FA+K + K + + E+ Sbjct: 375 LKIEDFILHKMLGKGSFGKVFLAEFKKTN-----QFFAIKALKKDVVLMDDDVECTMVEK 429 Query: 317 EILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 +L L +HPFL ++ F+T + VME+ GG Sbjct: 430 RVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGG 464
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 45.1 bits (105), Expect = 7e-05 Identities = 28/91 (30%), Positives = 49/91 (53%), Gaps = 1/91 (1%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREIL- 325 DF L+ +G G+ G V L++ G ++A+KV+ K S+ +++ S ER +L Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGA-----FYAVKVLQKKSILKKKEQSHIMAERSVLL 148 Query: 326 QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + + HPFL L F+T + V+++ GG Sbjct: 149 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGG 179
>GRK7_SPETR (Q9Z2G7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 548 Score = 44.7 bits (104), Expect = 9e-05 Identities = 28/90 (31%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 +FR+L + G G++ V + K +A K +DK L+ + A E+EIL+ Sbjct: 188 EFRVLGKGGFGEVCAVQVRNTGK--------MYACKKLDKKRLKKKGGEKMALLEKEILE 239 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ PF+ +L FE+ CLVM GG Sbjct: 240 KVNSPFIVSLAYAFESKTHLCLVMSLMNGG 269
>ST32A_HUMAN (Q8WU08) Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1)| Length = 396 Score = 44.7 bits (104), Expect = 9e-05 Identities = 26/89 (29%), Positives = 45/89 (50%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F +LR +G G G V + + + +AMK M+K R ++ E +I+Q Sbjct: 23 FEILRAIGKGSFGKVCIVQKND-----TKKMYAMKYMNKQKCVERNEVRNVFKELQIMQG 77 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L+HPFL L+ F+ ++ +V++ GG Sbjct: 78 LEHPFLVNLWYSFQDEEDMFMVVDLLLGG 106
>KGP2_MOUSE (Q61410) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 44.7 bits (104), Expect = 9e-05 Identities = 26/90 (28%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 + ++ LG G G V L ++ A FAMK + K + ++ +E+ IL+ Sbjct: 452 NLEIIATLGVGGFGRVELVKVKNENVA-----FAMKCIRKKHIVDTKQQEHVYSEKRILE 506 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L PF+ LY F+ +K+ +++E C GG Sbjct: 507 ELCSPFIVKLYRTFKDNKYVYMLLEACLGG 536
>KGP2_HUMAN (Q13237) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 44.7 bits (104), Expect = 9e-05 Identities = 26/90 (28%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 + ++ LG G G V L ++ A FAMK + K + ++ +E+ IL+ Sbjct: 452 NLEIIATLGVGGFGRVELVKVKNENVA-----FAMKCIRKKHIVDTKQQEHVYSEKRILE 506 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L PF+ LY F+ +K+ +++E C GG Sbjct: 507 ELCSPFIVKLYRTFKDNKYVYMLLEACLGG 536
>GRK7_HUMAN (Q8WTQ7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 44.7 bits (104), Expect = 9e-05 Identities = 28/90 (31%), Positives = 44/90 (48%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 +FR+L + G G++ V + K +A K +DK L+ + A E+EIL+ Sbjct: 193 EFRVLGKGGFGEVCAVQVKNTGK--------MYACKKLDKKRLKKKGGEKMALLEKEILE 244 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + PF+ +L FE+ CLVM GG Sbjct: 245 KVSSPFIVSLAYAFESKTHLCLVMSLMNGG 274
>MRCKA_HUMAN (Q5VT25) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha Length = 1732 Score = 44.7 bits (104), Expect = 9e-05 Identities = 29/107 (27%), Positives = 51/107 (47%) Frame = +2 Query: 98 WKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASL 277 W ++ L DF +L+ +G G G V + +L FAMK+++K + Sbjct: 59 WAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKV-----FAMKILNKWEM 113 Query: 278 ESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R + + ER++L D+ ++ TL+ F+ D LVM++ GG Sbjct: 114 LKRAETACFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGG 160
>SGK2_RAT (Q8R4U9) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) (Fragment) Length = 302 Score = 44.3 bits (103), Expect = 1e-04 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREIL- 325 DF L+ +G G+ G V L++ G ++A+KV+ K S+ ++ S ER +L Sbjct: 17 DFDFLKVIGKGNYGKVLLAKRKSDGA-----FYAVKVLQKKSILKNKEQSHIMAERNVLL 71 Query: 326 QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + + HPFL L F+T + V+++ GG Sbjct: 72 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGG 102
>KGP2_RAT (Q64595) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 44.3 bits (103), Expect = 1e-04 Identities = 26/90 (28%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 + ++ LG G G V L ++ A FAMK + K + ++ +E+ IL+ Sbjct: 452 NLEIIATLGVGGFGRVELVKVKNENIA-----FAMKCIRKKHIVDTKQQEHVYSEKRILE 506 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L PF+ LY F+ +K+ +++E C GG Sbjct: 507 ELCSPFIVKLYRTFKDNKYVYMLLEACLGG 536
>KPC1_COCHE (O42632) Protein kinase C-like (EC 2.7.11.13)| Length = 1174 Score = 44.3 bits (103), Expect = 1e-04 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 +G+ F L LG G+ G V L+E +A+KV+ K + ++ +E+ Sbjct: 844 IGLDHFNFLAVLGKGNFGKVMLAETKT-----TKQLYAIKVLKKEFIIENDEVESTRSEK 898 Query: 317 EILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 + + + HPFL L+A F+T+ VME+ GG Sbjct: 899 RVFLIANKERHPFLLNLHACFQTETRVYFVMEYISGG 935
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 44.3 bits (103), Expect = 1e-04 Identities = 29/90 (32%), Positives = 42/90 (46%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF + R LG G G VYL+ + A+KV+ K+ LE + E EI Sbjct: 139 DFEIGRPLGKGKFGNVYLARERESKFI-----LALKVLFKSQLEKAGVEHQLRREVEIQS 193 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L HP + LY +F L++++ PGG Sbjct: 194 HLRHPNILRLYGYFHDASRVYLILDYAPGG 223
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 44.3 bits (103), Expect = 1e-04 Identities = 29/90 (32%), Positives = 42/90 (46%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF + R LG G G VYL+ + A+KV+ K+ LE + E EI Sbjct: 139 DFEIGRPLGKGKFGNVYLARERESKFI-----LALKVLFKSQLEKAGVEHQLRREVEIQS 193 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L HP + LY +F L++++ PGG Sbjct: 194 HLRHPNILRLYGYFHDASRVYLILDYAPGG 223
>SID2_SCHPO (Q09898) Serine/threonine-protein kinase sid2 (EC 2.7.11.1)| Length = 607 Score = 44.3 bits (103), Expect = 1e-04 Identities = 28/91 (30%), Positives = 45/91 (49%) Frame = +2 Query: 146 GDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREIL 325 GDF+ + ++G G G+V+L+ A+K+M+K+ L ++ TER+IL Sbjct: 206 GDFQTITQVGQGGYGSVWLARKRD-----TKEIVALKIMNKSVLHKMDEIRHVLTERDIL 260 Query: 326 QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + +L L F+ L MEF PGG Sbjct: 261 TTANSEWLVRLLYAFQDTSNIYLAMEFVPGG 291
>SGK3_MOUSE (Q9ERE3) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 44.3 bits (103), Expect = 1e-04 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREIL- 325 DF L+ +G G G V L++ G ++A+KV+ K + +R++ ER +L Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDG-----KFYAVKVLQKKIVLNRKEQKHIMAERNVLL 215 Query: 326 QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + + HPFL L+ F+T + V++F GG Sbjct: 216 KNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG 246
>SGK3_HUMAN (Q96BR1) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) Length = 496 Score = 44.3 bits (103), Expect = 1e-04 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREIL- 325 DF L+ +G G G V L++ G ++A+KV+ K + +R++ ER +L Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDG-----KFYAVKVLQKKIVLNRKEQKHIMAERNVLL 215 Query: 326 QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + + HPFL L+ F+T + V++F GG Sbjct: 216 KNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG 246
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 44.3 bits (103), Expect = 1e-04 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF L + LG G G V+L+E + +FA+K + K + + E+ Sbjct: 375 LKIDDFILHKMLGKGSFGKVFLAEFKRTN-----QFFAIKALKKDVVLMDDDVECTMVEK 429 Query: 317 EILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 +L L +HPFL ++ F+T + VME+ GG Sbjct: 430 RVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGG 464
>ST32A_MOUSE (Q8BGW6) Serine/threonine-protein kinase 32A (EC 2.7.11.1)| Length = 398 Score = 43.9 bits (102), Expect = 2e-04 Identities = 26/89 (29%), Positives = 44/89 (49%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F +LR +G G G V + + +AMK M+K R ++ E +I+Q Sbjct: 23 FEILRAIGKGSFGKVCIVRKND-----TKKMYAMKYMNKQKCVERNEVRNVFKELQIMQG 77 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L+HPFL L+ F+ ++ +V++ GG Sbjct: 78 LEHPFLVNLWYSFQDEEDMFMVVDLLLGG 106
>KAPL_APLCA (P21901) Spermatozoon-associated protein kinase (EC 2.7.11.1) (SAK)| (C-APL-B) Length = 351 Score = 43.9 bits (102), Expect = 2e-04 Identities = 26/90 (28%), Positives = 44/90 (48%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 ++ L+R LG G G V LS+ GG +A+K+++K + +++ E+ IL Sbjct: 41 NYTLIRTLGSGSFGRVMLSQ---HGGDNPQKCYAIKILNKEKVVKMKQVEHTMNEKRILL 97 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + PF+ F+ +VMEF GG Sbjct: 98 SIGSPFVVRCLNAFKDTTNLYMVMEFVNGG 127
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 43.9 bits (102), Expect = 2e-04 Identities = 28/90 (31%), Positives = 44/90 (48%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF++ LG G VY +E G A+K++DK ++ + R + E +I Sbjct: 11 DFKVGNLLGKGSFAGVYRAESIHTGLE-----VAIKMIDKKAMYKAGMVQRVQNEVKIHC 65 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L HP + LY +FE + + LV+E C G Sbjct: 66 QLKHPSVLELYNYFEDNNYVYLVLEMCHNG 95
>DMPK_HUMAN (Q09013) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 639 Score = 43.9 bits (102), Expect = 2e-04 Identities = 28/103 (27%), Positives = 52/103 (50%) Frame = +2 Query: 110 LAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRR 289 + R + L DF +L+ +G G V + ++ + G +AMK+M+K + R Sbjct: 67 IVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQV-----YAMKIMNKWDMLKRG 121 Query: 290 KLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++S ER++L D ++ L+ F+ + + LVME+ GG Sbjct: 122 EVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGG 164
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 43.9 bits (102), Expect = 2e-04 Identities = 28/90 (31%), Positives = 43/90 (47%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF++ LG G VY +E G A+K++DK ++ + R + E +I Sbjct: 11 DFKVGNLLGKGSFAGVYRAESIHTGLE-----VAIKMIDKKAMYKAGMVQRVQNEVKIHC 65 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L HP + LY +FE + LV+E C G Sbjct: 66 QLKHPSILELYNYFEDSNYVYLVLEMCHNG 95
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 43.9 bits (102), Expect = 2e-04 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 2/94 (2%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLE--SRRKLSRAETER 316 +G++RLLR +G G+ V L+ G A+K++DK L S +KL R E Sbjct: 56 VGNYRLLRTIGKGNFAKVKLARHILTGRE-----VAIKIIDKTQLNPSSLQKLFR---EV 107 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 I++ L+HP + L+ ET+K LVME+ G Sbjct: 108 RIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAG 141
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 43.9 bits (102), Expect = 2e-04 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 2/94 (2%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLE--SRRKLSRAETER 316 +G++RLLR +G G+ V L+ G A+K++DK L S +KL R E Sbjct: 56 VGNYRLLRTIGKGNFAKVKLARHILTGRE-----VAIKIIDKTQLNPSSLQKLFR---EV 107 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 I++ L+HP + L+ ET+K LVME+ G Sbjct: 108 RIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAG 141
>MRCKA_RAT (O54874) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) Length = 1732 Score = 43.9 bits (102), Expect = 2e-04 Identities = 29/107 (27%), Positives = 50/107 (46%) Frame = +2 Query: 98 WKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASL 277 W ++ L DF +L+ +G G G V + +L FAMK+++K + Sbjct: 59 WAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKV-----FAMKILNKWEM 113 Query: 278 ESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R + + ER++L D ++ TL+ F+ D LVM++ GG Sbjct: 114 LKRAETACFREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGG 160
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 43.5 bits (101), Expect = 2e-04 Identities = 30/94 (31%), Positives = 42/94 (44%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L + DF L ++LG G G VY G A+KVM+K + + E Sbjct: 99 LSLDDFELGKKLGKGKFGKVYCVRHRSTGYI-----CALKVMEKEEIIKYNLQKQFRREV 153 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 EI L+HP L Y +F +K L+ME+ G Sbjct: 154 EIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNG 187
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 43.5 bits (101), Expect = 2e-04 Identities = 34/107 (31%), Positives = 46/107 (42%), Gaps = 6/107 (5%) Frame = +2 Query: 116 ARAGDGPLG------MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASL 277 ARAG PL + DF + + LG G G VY + G A+K M+K + Sbjct: 91 ARAGGVPLSKLQNLKLADFEIGKVLGKGKFGRVYCVRHIESGFV-----CALKAMEKKDI 145 Query: 278 ESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + E EI L HP L LY +F +K L+ME+ G Sbjct: 146 IQYNIEKQFRREVEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNG 192
>ST32B_MOUSE (Q9JJX8) Serine/threonine-protein kinase 32B (EC 2.7.11.1)| Length = 414 Score = 43.5 bits (101), Expect = 2e-04 Identities = 26/89 (29%), Positives = 45/89 (50%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F++LR +G G G V + + +AMK M+K R ++ E +I+Q Sbjct: 23 FQILRAIGKGSFGKVCIVQKRD-----TKKMYAMKYMNKQKCVERDEVRNVFRELQIMQG 77 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L+HPFL L+ F+ ++ +V++ GG Sbjct: 78 LEHPFLVNLWYSFQDEEDMFMVVDLLLGG 106
>ST32B_HUMAN (Q9NY57) Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2)| Length = 414 Score = 43.1 bits (100), Expect = 3e-04 Identities = 26/89 (29%), Positives = 45/89 (50%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F++LR +G G G V + + +AMK M+K R ++ E +I+Q Sbjct: 23 FQILRAIGKGSFGKVCIVQKRD-----TKKMYAMKYMNKQKCIERDEVRNVFRELQIMQG 77 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L+HPFL L+ F+ ++ +V++ GG Sbjct: 78 LEHPFLVNLWYSFQDEEDMFMVVDLLLGG 106
>MRCKG_HUMAN (Q6DT37) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 43.1 bits (100), Expect = 3e-04 Identities = 28/107 (26%), Positives = 52/107 (48%) Frame = +2 Query: 98 WKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASL 277 W + ++ + L DF +L+ +G G G V + G FAMK++ K + Sbjct: 53 WASPFVSKVKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQI-----FAMKMLHKWEM 107 Query: 278 ESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R + + ER++L D ++ TL+ F+ +++ LVM++ GG Sbjct: 108 LKRAETACFREERDVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGG 154
>SGK2_MOUSE (Q9QZS5) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 367 Score = 43.1 bits (100), Expect = 3e-04 Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREIL- 325 DF L+ +G G+ G V L++ G ++A+KV+ K S+ ++ + ER +L Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGA-----FYAVKVLQKKSILKNKEQNHIMAERNVLL 88 Query: 326 QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + + HPFL L F+T + V+++ GG Sbjct: 89 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGG 119
>ROCK2_BOVIN (Q28021) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 43.1 bits (100), Expect = 3e-04 Identities = 25/90 (27%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 D+ +++ +G G G V L +AMK++ K + R + ER+I+ Sbjct: 91 DYDVVKVIGRGAFGEVQLVRHKASQKV-----YAMKLLSKFEMIKRSDSAFFWEERDIMA 145 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + P++ L+ F+ DK+ +VME+ PGG Sbjct: 146 FANSPWVVQLFCAFQDDKYLYMVMEYMPGG 175
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 43.1 bits (100), Expect = 3e-04 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Frame = +2 Query: 140 GMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 G DF L+ +G G G VYL +AMKV+ K + R++++ ER+ Sbjct: 262 GPDDFVPLKLIGKGTFGQVYLVRKKDTERV-----YAMKVLSKKVIVRRKEVAHTVGERD 316 Query: 320 IL---QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 IL D PF+ L F+T K LV ++ GG Sbjct: 317 ILVQTSAADSPFIVALRFSFQTPKDLYLVTDYMAGG 352
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 42.7 bits (99), Expect = 3e-04 Identities = 29/83 (34%), Positives = 42/83 (50%) Frame = +2 Query: 167 RLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQLLDHPF 346 +LG G G VY KG +A+K K L++ ++R E EI++ LDHP Sbjct: 76 KLGQGTYGCVY-----KGIDKVTNQLYAIKEEKKDRLKN---INRFFQEIEIMKKLDHPN 127 Query: 347 LPTLYAHFETDKFACLVMEFCPG 415 + LY +E D + L+ME C G Sbjct: 128 IVKLYETYENDNYIYLIMELCSG 150
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 42.7 bits (99), Expect = 3e-04 Identities = 29/92 (31%), Positives = 43/92 (46%) Frame = +2 Query: 143 MGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREI 322 +G F + + LG G G VYL++ K G A+K + K+ L + + E EI Sbjct: 86 IGMFEIGKPLGKGKFGRVYLAKEKKTGFI-----VALKTLHKSELVQSKIEKQVRREIEI 140 Query: 323 LQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L H + LY HF +K L++EF G Sbjct: 141 QSNLRHKNILRLYGHFHDEKRIYLILEFAGRG 172
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 42.7 bits (99), Expect = 3e-04 Identities = 29/83 (34%), Positives = 42/83 (50%) Frame = +2 Query: 167 RLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQLLDHPF 346 +LG G G VY KG +A+K K L++ ++R E EI++ LDHP Sbjct: 76 KLGQGTYGCVY-----KGIDKVTNQLYAIKEEKKDRLKN---INRFFQEIEIMKKLDHPN 127 Query: 347 LPTLYAHFETDKFACLVMEFCPG 415 + LY +E D + L+ME C G Sbjct: 128 IVKLYETYENDNYIYLIMELCSG 150
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 42.7 bits (99), Expect = 3e-04 Identities = 30/90 (33%), Positives = 41/90 (45%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF + R LG G G VYL+ + A+KV+ KA LE + E EI Sbjct: 132 DFEIGRPLGKGKFGNVYLAREKQSKFI-----LALKVLFKAQLEKAGVEHQLRREVEIQS 186 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L HP + LY +F L++E+ P G Sbjct: 187 HLRHPNILRLYGYFHDATRVYLILEYAPLG 216
>DBF20_YEAST (P32328) Serine/threonine-protein kinase DBF20 (EC 2.7.11.1)| Length = 564 Score = 42.7 bits (99), Expect = 3e-04 Identities = 28/90 (31%), Positives = 44/90 (48%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF++L ++G G G VYL++ A+K+++K L + + TER+IL Sbjct: 168 DFQILTQVGQGGYGQVYLAKKKDSDEI-----CALKILNKKLLFKLNETNHVLTERDILT 222 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +L L F+ + L MEF PGG Sbjct: 223 TTRSDWLVKLLYAFQDPESLYLAMEFVPGG 252
>RK_BOVIN (P28327) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 561 Score = 42.7 bits (99), Expect = 3e-04 Identities = 30/95 (31%), Positives = 44/95 (46%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+G F R LG G G V+ ++ G +A K ++K L+ R+ A E Sbjct: 181 PMGEDWFLDFRVLGRGGFGEVFACQMKATGKL-----YACKKLNKKRLKKRKGYQGAMVE 235 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++IL + F+ +L FET CLVM GG Sbjct: 236 KKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGG 270
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 42.7 bits (99), Expect = 3e-04 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 + + DFRLL +G G V +E +A+K++ K + +TE+ Sbjct: 248 VSLNDFRLLTVIGRGSYAKVVQAE-----HVSTRQIYAIKIIKKEMFNEDEDIDWVQTEK 302 Query: 317 EILQLL-DHPFLPTLYAHFETDKFACLVMEFCPGG 418 + + ++PFL L++ F+T+ V+EF PGG Sbjct: 303 SVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGG 337
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 42.7 bits (99), Expect = 3e-04 Identities = 25/57 (43%), Positives = 34/57 (59%) Frame = +2 Query: 248 AMKVMDKASLESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 A+K+MDK +L S L R +TE E L+ L H + LY ET +V+E+CPGG Sbjct: 38 AIKIMDKNTLGS--DLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGG 92
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 42.7 bits (99), Expect = 3e-04 Identities = 24/57 (42%), Positives = 34/57 (59%) Frame = +2 Query: 248 AMKVMDKASLESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 A+K+MDK +L S L R +TE + L+ L H + LY ET +V+E+CPGG Sbjct: 38 AIKIMDKNALGS--DLPRVKTEIDALKSLRHQHICQLYHVLETKNKIFMVLEYCPGG 92
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 42.4 bits (98), Expect = 4e-04 Identities = 24/90 (26%), Positives = 42/90 (46%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF+ + LG G TV L+ + +A+K+++K + K+ ER+++ Sbjct: 84 DFKFGKILGEGSFSTVVLAR-----ELATSREYAIKILEKRHIIKENKVPYVTRERDVMS 138 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LDHPF LY F+ D+ + + G Sbjct: 139 RLDHPFFVKLYFTFQDDEKLYFGLSYAKNG 168
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 42.4 bits (98), Expect = 4e-04 Identities = 24/90 (26%), Positives = 42/90 (46%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF+ + LG G TV L+ + +A+K+++K + K+ ER+++ Sbjct: 84 DFKFGKILGEGSFSTVVLAR-----ELATSREYAIKILEKRHIIKENKVPYVTRERDVMS 138 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LDHPF LY F+ D+ + + G Sbjct: 139 RLDHPFFVKLYFTFQDDEKLYFGLSYAKNG 168
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 42.4 bits (98), Expect = 4e-04 Identities = 29/90 (32%), Positives = 42/90 (46%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF + R LG G G VYL+ K A+KV+ K+ +E + E EI Sbjct: 76 DFEIGRPLGKGKFGNVYLAREKKSHFI-----VALKVLFKSQIEKEGVEHQLRREIEIQA 130 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L HP + LY +F + L++E+ P G Sbjct: 131 HLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
>NEK11_MOUSE (Q8C0Q4) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 628 Score = 42.4 bits (98), Expect = 4e-04 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 2/88 (2%) Frame = +2 Query: 158 LLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLE--SRRKLSRAETEREILQL 331 L ++LG G GTVYL K P +KV+ + S+ + + +A E ++L Sbjct: 32 LQQKLGSGSFGTVYLVSDKKA-----KPGEELKVLKEISVGELNPNETVQANVEAQLLSR 86 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPG 415 L HP + +A F + C++ E+C G Sbjct: 87 LHHPAIVRFHASFMEQETFCIITEYCEG 114
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 42.4 bits (98), Expect = 4e-04 Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 5/94 (5%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLS-ELSKGGGAGRAPWFAMKVMDKASL----ESRRKLSRAETER 316 + ++R LG G V L+ E++ G W+A+K+++K + +R + E Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSG------KWYAIKIINKRKILLTSSEKRATEMFQREI 220 Query: 317 EILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +IL+ L HP + + FE D +VME+ GG Sbjct: 221 DILKSLHHPGVVQCHEIFENDDELFIVMEYVEGG 254
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 42.4 bits (98), Expect = 4e-04 Identities = 24/90 (26%), Positives = 42/90 (46%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF+ + LG G TV L+ + +A+K+++K + K+ ER+++ Sbjct: 81 DFKFGKILGEGSFSTVVLAR-----ELATSREYAIKILEKRHIIKENKVPYVTRERDVMS 135 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 LDHPF LY F+ D+ + + G Sbjct: 136 RLDHPFFVKLYFTFQDDEKLYFGLSYAKNG 165
>KPC1_CANAL (P43057) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1097 Score = 42.4 bits (98), Expect = 4e-04 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 +G+ DF+ L LG G+ G V L+E + A+KV+ K + + ++E+ Sbjct: 765 VGLDDFQFLAVLGKGNFGKVMLAE-----SRHTSKLCAIKVLKKDFIVENDEAESVKSEK 819 Query: 317 EILQLLD---HPFLPTLYAHFETDKFACLVMEFCPGG 418 + + HPFL L+ F+T+ VME+ GG Sbjct: 820 RVFLTANKEMHPFLLNLHCCFQTENRIYFVMEYISGG 856
>MRCKG_MOUSE (Q80UW5) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 42.4 bits (98), Expect = 4e-04 Identities = 28/107 (26%), Positives = 54/107 (50%) Frame = +2 Query: 98 WKAVLAARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASL 277 W + + + L DF +L+ +G G G V + + G+G+ FAMK++ K + Sbjct: 53 WASPFVTKVKELRLQRDDFEILKVIGRGAFGEV---AVVRQRGSGQI--FAMKMLHKWEM 107 Query: 278 ESRRKLSRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 R + + ER++L D ++ L+ F+ +++ LVM++ GG Sbjct: 108 LKRAETACFREERDVLVKGDSRWVTALHYAFQDEEYLYLVMDYYAGG 154
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 42.0 bits (97), Expect = 6e-04 Identities = 24/90 (26%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 D+ +++ +G G G V L +AMK++ K + R + ER+I+ Sbjct: 82 DYDVVKVIGRGAFGEVQLVRHKASQKV-----YAMKLLSKFEMIKRSDSAFFWEERDIMA 136 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + P++ L+ F+ D++ +VME+ PGG Sbjct: 137 FANSPWVVQLFCAFQDDRYLYMVMEYMPGG 166
>ROCK2_MOUSE (P70336) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 42.0 bits (97), Expect = 6e-04 Identities = 24/90 (26%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 D+ +++ +G G G V L +AMK++ K + R + ER+I+ Sbjct: 91 DYDVVKVIGRGAFGEVQLVRHKASQKV-----YAMKLLSKFEMIKRSDSAFFWEERDIMA 145 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + P++ L+ F+ D++ +VME+ PGG Sbjct: 146 FANSPWVVQLFCAFQDDRYLYMVMEYMPGG 175
>GRK5_RAT (Q62833) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 42.0 bits (97), Expect = 6e-04 Identities = 28/95 (29%), Positives = 45/95 (47%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FR R LG G G V ++ G +A K ++K ++ R+ S A E Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATG-----KMYACKRLEKKRIKKRKGESMALNE 234 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++IL+ ++ F+ L +ET CLV+ GG Sbjct: 235 KQILEKVNSQFVVNLAYAYETKDALCLVLTIMNGG 269
>GRK5_MOUSE (Q8VEB1) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 42.0 bits (97), Expect = 6e-04 Identities = 28/95 (29%), Positives = 45/95 (47%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FR R LG G G V ++ G +A K ++K ++ R+ S A E Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATG-----KMYACKRLEKKRIKKRKGESMALNE 234 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++IL+ ++ F+ L +ET CLV+ GG Sbjct: 235 KQILEKVNSQFVVNLAYAYETKDALCLVLTIMNGG 269
>GRK5_HUMAN (P34947) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 42.0 bits (97), Expect = 6e-04 Identities = 28/95 (29%), Positives = 45/95 (47%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FR R LG G G V ++ G +A K ++K ++ R+ S A E Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATG-----KMYACKRLEKKRIKKRKGESMALNE 234 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++IL+ ++ F+ L +ET CLV+ GG Sbjct: 235 KQILEKVNSQFVVNLAYAYETKDALCLVLTIMNGG 269
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 42.0 bits (97), Expect = 6e-04 Identities = 29/96 (30%), Positives = 47/96 (48%) Frame = +2 Query: 131 GPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAET 310 GP+ +G + + LG G+ V L G A+K++DK+ L++ L + Sbjct: 13 GPVRVGFYDIEGTLGKGNFAVVKL-----GRHRTTKTEVAIKIIDKSQLDAVN-LEKIYR 66 Query: 311 EREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 E +I+++LDHP + LY ET LV E+ G Sbjct: 67 EVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNG 102
>GRK5_BOVIN (P43249) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 41.6 bits (96), Expect = 7e-04 Identities = 28/95 (29%), Positives = 45/95 (47%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FR R LG G G V ++ G +A K ++K ++ R+ S A E Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATG-----KMYACKRLEKKRIKKRKGESMALNE 234 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++IL+ ++ F+ L +ET CLV+ GG Sbjct: 235 KQILEKVNSRFVVNLAYAYETKDALCLVLTIMNGG 269
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 41.6 bits (96), Expect = 7e-04 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 1/91 (1%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF L LG G G V L+EL ++A+K + K + + ER++L Sbjct: 314 DFHFLAVLGKGSFGKVLLAELRD-----TTYYYAIKCLKKDVVLEDDDVDSTLIERKVLA 368 Query: 329 L-LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L HP+L L+ F+T+ VME+ GG Sbjct: 369 LGTKHPYLCHLFCTFQTESHLFFVMEYLNGG 399
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 41.6 bits (96), Expect = 7e-04 Identities = 24/90 (26%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 D+ +++ +G G G V L +AMK++ K + R + ER+I+ Sbjct: 75 DYEVVKVIGRGAFGEVQLVRHKSTRKV-----YAMKLLSKFEMIKRSDSAFFWEERDIMA 129 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + P++ L+ F+ D++ +VME+ PGG Sbjct: 130 FANSPWVVQLFYAFQDDRYLYMVMEYMPGG 159
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 41.6 bits (96), Expect = 7e-04 Identities = 24/90 (26%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 D+ +++ +G G G V L +AMK++ K + R + ER+I+ Sbjct: 75 DYEVVKVIGRGAFGEVQLVRHKSTRKV-----YAMKLLSKFEMIKRSDSAFFWEERDIMA 129 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + P++ L+ F+ D++ +VME+ PGG Sbjct: 130 FANSPWVVQLFYAFQDDRYLYMVMEYMPGG 159
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 41.6 bits (96), Expect = 7e-04 Identities = 24/90 (26%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 D+ +++ +G G G V L +AMK++ K + R + ER+I+ Sbjct: 75 DYEVVKVIGRGAFGEVQLVRHKSTRKV-----YAMKLLSKFEMIKRSDSAFFWEERDIMA 129 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + P++ L+ F+ D++ +VME+ PGG Sbjct: 130 FANSPWVVQLFYAFQDDRYLYMVMEYMPGG 159
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 41.6 bits (96), Expect = 7e-04 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 1/100 (1%) Frame = +2 Query: 122 AGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSR 301 +G G + DF L LG G G V L+E G +A+K++ K + + Sbjct: 315 SGMGVVRASDFNFLSVLGKGSFGKVMLAEKK-----GTDELYAIKILKKDVIIQDDDVEC 369 Query: 302 AETEREILQLLDHP-FLPTLYAHFETDKFACLVMEFCPGG 418 TE+ +L L P FL L++ F+T VMEF GG Sbjct: 370 TMTEKRVLGLPSKPAFLTALHSCFQTMDRLFFVMEFVNGG 409
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 41.6 bits (96), Expect = 7e-04 Identities = 24/90 (26%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 D+ +++ +G G G V L +AMK++ K + R + ER+I+ Sbjct: 75 DYEVVKVIGRGAFGEVQLVRHKSTRKV-----YAMKLLSKFEMIKRSDSAFFWEERDIMA 129 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + P++ L+ F+ D++ +VME+ PGG Sbjct: 130 FANSPWVVQLFYAFQDDRYLYMVMEYMPGG 159
>NEK11_HUMAN (Q8NG66) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 645 Score = 41.6 bits (96), Expect = 7e-04 Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 3/89 (3%) Frame = +2 Query: 158 LLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLE--SRRKLSRAETEREILQL 331 L ++LG G GTVYL K +KV+ + S+ + + +A E ++L Sbjct: 31 LQQKLGSGSFGTVYLVSDKKAKRGEE-----LKVLKEISVGELNPNETVQANLEAQLLSK 85 Query: 332 LDHPFLPTLYAHF-ETDKFACLVMEFCPG 415 LDHP + +A F E D F C++ E+C G Sbjct: 86 LDHPAIVKFHASFVEQDNF-CIITEYCEG 113
>NEK11_MACFA (Q8WNU8) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 637 Score = 41.6 bits (96), Expect = 7e-04 Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 3/89 (3%) Frame = +2 Query: 158 LLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLE--SRRKLSRAETEREILQL 331 L ++LG G GTVYL K +KV+ + S+ + + +A E ++L Sbjct: 31 LQQKLGSGSFGTVYLVSDKKAKRGEE-----LKVLKEISVGELNPNETVQANLEAQLLSK 85 Query: 332 LDHPFLPTLYAHF-ETDKFACLVMEFCPG 415 LDHP + +A F E D F C++ E+C G Sbjct: 86 LDHPAIVKFHASFVEQDNF-CIITEYCEG 113
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 41.2 bits (95), Expect = 0.001 Identities = 29/96 (30%), Positives = 47/96 (48%) Frame = +2 Query: 131 GPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAET 310 GP+ +G + + LG G+ V L G A+K++DK+ L++ L + Sbjct: 13 GPVRVGFYDIEGTLGKGNFAVVKL-----GRHRITKTEVAIKIIDKSQLDAVN-LEKIYR 66 Query: 311 EREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 E +I+++LDHP + LY ET LV E+ G Sbjct: 67 EVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNG 102
>ARBK2_RAT (P26819) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 41.2 bits (95), Expect = 0.001 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 3/97 (3%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L M DF + R +G G G VY + G +AMK +DK ++ ++ + A ER Sbjct: 186 LSMNDFSVHRIIGRGGFGEVYGCRKADTG-----KMYAMKCLDKKRVKMKQGETLALNER 240 Query: 317 EILQLL---DHPFLPTLYAHFETDKFACLVMEFCPGG 418 +L L+ D PF+ + F T C +++ GG Sbjct: 241 IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGG 277
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 41.2 bits (95), Expect = 0.001 Identities = 29/96 (30%), Positives = 47/96 (48%) Frame = +2 Query: 131 GPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAET 310 GP+ +G + + LG G+ V L G A+K++DK+ L++ L + Sbjct: 13 GPVRVGFYDIEGTLGKGNFAVVKL-----GRHRITKTEVAIKIIDKSQLDAVN-LEKIYR 66 Query: 311 EREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 E +I+++LDHP + LY ET LV E+ G Sbjct: 67 EVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNG 102
>ST32C_HUMAN (Q86UX6) Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE)| (YANK3) Length = 486 Score = 41.2 bits (95), Expect = 0.001 Identities = 26/89 (29%), Positives = 44/89 (49%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F++LR +G G G V + + +AMK M+K R ++ E EILQ Sbjct: 93 FQILRAIGKGSFGKVCIVQKRD-----TEKMYAMKYMNKQQCIERDEVRNVFRELEILQE 147 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++H FL L+ F+ ++ +V++ GG Sbjct: 148 IEHVFLVNLWYSFQDEEDMFMVVDLLLGG 176
>RK_HUMAN (Q15835) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 563 Score = 41.2 bits (95), Expect = 0.001 Identities = 27/90 (30%), Positives = 42/90 (46%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DFR+L + G G++ + K +A K ++K L+ R+ A E++IL Sbjct: 192 DFRVLGKGGFGEVSACQMKATGK--------LYACKKLNKKRLKKRKGYQGAMVEKKILM 243 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + F+ +L FET CLVM GG Sbjct: 244 KVHSRFIVSLAYAFETKADLCLVMTIMNGG 273
>ST32C_MOUSE (Q8QZV4) Serine/threonine-protein kinase 32C (EC 2.7.11.1)| Length = 488 Score = 41.2 bits (95), Expect = 0.001 Identities = 26/89 (29%), Positives = 44/89 (49%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 F++LR +G G G V + + +AMK M+K R ++ E EILQ Sbjct: 94 FQILRAIGKGSFGKVCIVQKRD-----TEKMYAMKYMNKQQCIERDEVRNVFRELEILQE 148 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++H FL L+ F+ ++ +V++ GG Sbjct: 149 IEHVFLVNLWYSFQDEEDMFMVVDLLLGG 177
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 41.2 bits (95), Expect = 0.001 Identities = 24/90 (26%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 D+ +++ +G G G V L +AMK++ K + R + ER+I+ Sbjct: 91 DYDVVKVIGRGAFGEVQLVRHKASQKV-----YAMKLLSKFEMIKRSDSAFFWEERDIMA 145 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + P++ L+ F+ D++ +VME+ PGG Sbjct: 146 FANSPWVVQLFYAFQDDRYLYMVMEYMPGG 175
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 41.2 bits (95), Expect = 0.001 Identities = 26/90 (28%), Positives = 45/90 (50%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 +++L R LG G G V ++E + G A+K++++ +++ + E +IL+ Sbjct: 41 NYKLGRTLGIGSFGRVKIAEHALTGHK-----VAIKILNRRKIKNMEMEEKVRREIKILR 95 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 L HP + LY ET LVME+ G Sbjct: 96 LFMHPHIIRLYEVIETPTDIYLVMEYVNSG 125
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 41.2 bits (95), Expect = 0.001 Identities = 27/95 (28%), Positives = 46/95 (48%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FR R LG G G V ++ G +A K ++K ++ R+ + A E Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATG-----KMYACKKLEKKRIKKRKGEAMALNE 234 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++IL+ ++ F+ +L +ET CLV+ GG Sbjct: 235 KQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGG 269
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 41.2 bits (95), Expect = 0.001 Identities = 27/95 (28%), Positives = 46/95 (48%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FR R LG G G V ++ G +A K ++K ++ R+ + A E Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATG-----KMYACKKLEKKRIKKRKGEAMALNE 234 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++IL+ ++ F+ +L +ET CLV+ GG Sbjct: 235 KQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGG 269
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 41.2 bits (95), Expect = 0.001 Identities = 27/95 (28%), Positives = 46/95 (48%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FR R LG G G V ++ G +A K ++K ++ R+ + A E Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATG-----KMYACKKLEKKRIKKRKGEAMALNE 234 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++IL+ ++ F+ +L +ET CLV+ GG Sbjct: 235 KQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGG 269
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 41.2 bits (95), Expect = 0.001 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L M DF + R +G G G VY + G +AMK +DK ++ ++ A ER Sbjct: 186 LTMNDFSVHRIIGRGGFGEVYGCRKADTG-----KMYAMKCLDKKRIKMKQGEMLALNER 240 Query: 317 EILQL----LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 +LQ +D PF+ + F T C +++ GG Sbjct: 241 NMLQAVSTGIDCPFIVCMTYAFHTPDKLCFILDLMNGG 278
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 41.2 bits (95), Expect = 0.001 Identities = 28/101 (27%), Positives = 46/101 (45%) Frame = +2 Query: 116 ARAGDGPLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKL 295 A AG G L +G+F + +G G G V +G A+K++++ ++ + Sbjct: 12 ALAGTGHLKIGNFVIKETIGKGAFGAV-----KRGTHIQTGYDVAIKILNRGRMKGLGTV 66 Query: 296 SRAETEREILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ E + LQ L HP + L+ T LVME GG Sbjct: 67 NKTRNEIDNLQKLTHPHITRLFRVISTPSDIFLVMELVSGG 107
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DF ++ +G G G V L+E G +A+KV+ K + + E++IL Sbjct: 370 DFNFVKVIGKGSFGKVLLAERR-----GTDELYAVKVLRKDVIIQTDDMELPMNEKKILA 424 Query: 329 LLDHP-FLPTLYAHFETDKFACLVMEFCPGG 418 L P FL ++++ F+T VME+C GG Sbjct: 425 LSGRPPFLVSMHSCFQTMDRLFFVMEYCKGG 455
>GRK4_RAT (P70507) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 575 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/95 (29%), Positives = 44/95 (46%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FR R LG G G V ++ G +A K ++K ++ R+ + A E Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATG-----KMYACKKLEKKRIKKRKGEAMALNE 234 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + IL+ L F+ +L +ET CLV+ GG Sbjct: 235 KRILEKLHSRFVVSLAYTYETKDALCLVLTIMNGG 269
>ATG1_YEAST (P53104) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Autophagy protein 3) (Cytoplasm to vacuole targeting protein 10) Length = 897 Score = 40.8 bits (94), Expect = 0.001 Identities = 25/91 (27%), Positives = 45/91 (49%) Frame = +2 Query: 146 GDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREIL 325 G++ + +G G TVY L+ + ++ A+K + +A L++++ L E E IL Sbjct: 22 GNYTAEKEIGKGSFATVYRGHLT----SDKSQHVAIKEVSRAKLKNKKLLENLEIEIAIL 77 Query: 326 QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + + HP + L T L+ME+C G Sbjct: 78 KKIKHPHIVGLIDCERTSTDFYLIMEYCALG 108
>GRK4_MOUSE (O70291) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 574 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/95 (29%), Positives = 44/95 (46%) Frame = +2 Query: 134 PLGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETE 313 P+ FR R LG G G V ++ G +A K ++K ++ R+ + A E Sbjct: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATG-----KMYACKKLEKKRIKKRKGEAMALNE 234 Query: 314 REILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + IL+ L F+ +L +ET CLV+ GG Sbjct: 235 KRILEKLHSRFVVSLAYTYETKDALCLVLTIMNGG 269
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 40.8 bits (94), Expect = 0.001 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 3/97 (3%) Frame = +2 Query: 137 LGMGDFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETER 316 L M DF + R +G G G VY + G +AMK +DK ++ ++ + A ER Sbjct: 186 LTMNDFSVHRIIGRGGFGEVYGCRKADTG-----KMYAMKCLDKKRIKMKQGETLALNER 240 Query: 317 EILQLL---DHPFLPTLYAHFETDKFACLVMEFCPGG 418 +L L+ D PF+ + F T C +++ GG Sbjct: 241 IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGG 277
>RAN1_SCHPO (P08092) Negative regulator of sexual conjugation and meiosis (EC| 2.7.11.1) Length = 470 Score = 40.8 bits (94), Expect = 0.001 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Frame = +2 Query: 143 MGD-FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETERE 319 +GD R + +G G G VY +E G +A+K + K L ++K +A Sbjct: 14 LGDSLRFVSIIGAGAYGVVYKAEDIYDGTL-----YAVKALCKDGLNEKQKKLQARELAL 68 Query: 320 ILQLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++ HP++ TL+ ET+ +V+++CP G Sbjct: 69 HARVSSHPYIITLHRVLETEDAIYVVLQYCPNG 101
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 40.4 bits (93), Expect = 0.002 Identities = 37/111 (33%), Positives = 47/111 (42%), Gaps = 9/111 (8%) Frame = +2 Query: 113 AARAGDGPLGMG--------DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDK 268 A RA PLG DF L LG G G V L E FA+KV+ K Sbjct: 327 APRASTLPLGSSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKT-----TKELFAIKVLKK 381 Query: 269 ASLESRRKLSRAETEREILQLLDHP-FLPTLYAHFETDKFACLVMEFCPGG 418 + + TE+ +L L + P FL L++ F+T VMEF GG Sbjct: 382 DVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGG 432
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 40.4 bits (93), Expect = 0.002 Identities = 24/90 (26%), Positives = 44/90 (48%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 D+ + +G G G V L + G + A+K+M + ++ + E+ +L+ Sbjct: 45 DWDTIATVGTGTFGRVNLVKEKTG-----RQYCALKIMSIPDVIRLKQEQHVQNEKAVLK 99 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 ++HPFL L ++F ++MEF PGG Sbjct: 100 EINHPFLIKLLWTGHDNRFLYMLMEFVPGG 129
>STK10_MOUSE (O55098) Serine/threonine-protein kinase 10 (EC 2.7.11.1)| (Lymphocyte-oriented kinase) Length = 966 Score = 40.4 bits (93), Expect = 0.002 Identities = 28/89 (31%), Positives = 43/89 (48%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 + ++ LG G G VY ++ + G A KV++ S E +L E EIL Sbjct: 36 WEIVGELGDGAFGKVYKAKNKETGALAAA-----KVIETKSEE---ELEDYIVEIEILAT 87 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 DHP++ L + D +++EFCPGG Sbjct: 88 CDHPYIVKLLGAYYYDGKLWIMIEFCPGG 116
>SGK1_RABIT (Q9XT18) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 40.4 bits (93), Expect = 0.002 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREIL- 325 DF L+ +G G G V L+ ++A+KV+ K ++ +++ +ER +L Sbjct: 97 DFHFLKVIGKGSFGKVLLARHK-----AEEAFYAVKVLQKKAILKKKEEKHIMSERNVLL 151 Query: 326 QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + + HPFL L+ F+T V+++ GG Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGG 182
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 40.4 bits (93), Expect = 0.002 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREIL- 325 DF L+ +G G G V L+ ++A+KV+ K ++ +++ +ER +L Sbjct: 97 DFHFLKVIGKGSFGKVLLARHK-----AEEAFYAVKVLQKKAILKKKEEKHIMSERNVLL 151 Query: 326 QLLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + + HPFL L+ F+T V+++ GG Sbjct: 152 KNVKHPFLVGLHFSFQTADKLYFVLDYINGG 182
>RK_RAT (Q63651) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 564 Score = 40.4 bits (93), Expect = 0.002 Identities = 27/90 (30%), Positives = 41/90 (45%) Frame = +2 Query: 149 DFRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQ 328 DFR+L + G G++ + K +A K ++K L+ R+ A E+ IL Sbjct: 192 DFRVLGKGGFGEVSACQMKATGK--------MYACKKLNKKRLKKRKGYQGAIVEKRILA 243 Query: 329 LLDHPFLPTLYAHFETDKFACLVMEFCPGG 418 + F+ +L FET CLVM GG Sbjct: 244 KVHSRFIVSLAYAFETKTDLCLVMTIMNGG 273
>STK10_HUMAN (O94804) Serine/threonine-protein kinase 10 (EC 2.7.11.1)| (Lymphocyte-oriented kinase) Length = 968 Score = 40.4 bits (93), Expect = 0.002 Identities = 28/89 (31%), Positives = 43/89 (48%) Frame = +2 Query: 152 FRLLRRLGCGDIGTVYLSELSKGGGAGRAPWFAMKVMDKASLESRRKLSRAETEREILQL 331 + ++ LG G G VY ++ + G A KV++ S E +L E EIL Sbjct: 36 WEIVGELGDGAFGKVYKAKNKETGALAAA-----KVIETKSEE---ELEDYIVEIEILAT 87 Query: 332 LDHPFLPTLYAHFETDKFACLVMEFCPGG 418 DHP++ L + D +++EFCPGG Sbjct: 88 CDHPYIVKLLGAYYHDGKLWIMIEFCPGG 116 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.313 0.140 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,201,007 Number of Sequences: 219361 Number of extensions: 297976 Number of successful extensions: 1385 Number of sequences better than 10.0: 472 Number of HSP's better than 10.0 without gapping: 1320 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1335 length of database: 80,573,946 effective HSP length: 100 effective length of database: 58,637,846 effective search space used: 2228238148 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits)
