>AVP_PHAAU (P21616) Pyrophosphate-energized vacuolar membrane proton pump (EC|
           3.6.1.1) (Pyrophosphate-energized inorganic
           pyrophosphatase) (H(+)-PPase) (Vacuolar
           H(+)-pyrophosphatase)
          Length = 764

 Score =  107 bits (266), Expect = 2e-23
 Identities = 62/143 (43%), Positives = 76/143 (53%)
 Frame = +3

Query: 69  GARAMGFSAADAVIPACAVIGIAFALWQWFLVAXVKVSAYAPAGNGVHGRPVFRTXXXXX 248
           GA  +     + +IP CAVIGIAFAL+QW LV+ VK+SA   A      +  +       
Sbjct: 1   GAAILPDLGTEILIPVCAVIGIAFALFQWLLVSKVKLSAVRDASPNAAAKNGYNDYLIEE 60

Query: 249 XXXXXXXXXXXXXXXXXXXXXXPAAVARCAEIQNAISVGAXSFLFTQYKYLAAFTVIFAV 428
                                    V +CAEIQNAIS GA SFLFT+YKY+  F V FA+
Sbjct: 61  EEGINDHN----------------VVVKCAEIQNAISEGATSFLFTEYKYVGIFMVAFAI 104

Query: 429 VIFLFLGSVHRFSTASQPCQYTK 497
           +IFLFLGSV  FST+ Q C Y K
Sbjct: 105 LIFLFLGSVEGFSTSPQACSYDK 127

>AVP1_ARATH (P31414) Pyrophosphate-energized vacuolar membrane proton pump 1|
           (EC 3.6.1.1) (Pyrophosphate-energized inorganic
           pyrophosphatase 1) (H(+)-PPase 1) (Vacuolar proton
           pyrophosphatase 1) (Vacuolar proton pyrophosphatase 3)
          Length = 770

 Score =  100 bits (249), Expect = 2e-21
 Identities = 57/137 (41%), Positives = 77/137 (56%), Gaps = 6/137 (4%)
 Frame = +3

Query: 99  DAVIPACAVIGIAFALWQWFLVAXVKV------SAYAPAGNGVHGRPVFRTXXXXXXXXX 260
           + ++P CAVIGIAF+L+QW++V+ VK+      S+   A NG +G   +           
Sbjct: 13  EILVPICAVIGIAFSLFQWYVVSRVKLTSDLGASSSGGANNGKNGYGDY----------- 61

Query: 261 XXXXXXXXXXXXXXXXXXPAAVARCAEIQNAISVGAXSFLFTQYKYLAAFTVIFAVVIFL 440
                              + VA+CAEIQ AIS GA SFLFT+YKY+  F + FA VIF+
Sbjct: 62  --------LIEEEEGVNDQSVVAKCAEIQTAISEGATSFLFTEYKYVGVFMIFFAAVIFV 113

Query: 441 FLGSVHRFSTASQPCQY 491
           FLGSV  FST ++PC Y
Sbjct: 114 FLGSVEGFSTDNKPCTY 130

>AVP_HORVU (Q06572) Pyrophosphate-energized vacuolar membrane proton pump (EC|
           3.6.1.1) (Pyrophosphate-energized inorganic
           pyrophosphatase) (H(+)-PPase)
          Length = 762

 Score =  100 bits (249), Expect = 2e-21
 Identities = 61/144 (42%), Positives = 76/144 (52%), Gaps = 5/144 (3%)
 Frame = +3

Query: 81  MGFSAADAVIPACAVIGIAFALWQWFLVAXVKV-----SAYAPAGNGVHGRPVFRTXXXX 245
           +G    + +IP C VIGI FA+ QWF+V+ VKV     SA A A NG +G  +       
Sbjct: 4   LGELGTEILIPVCGVIGIVFAVAQWFIVSKVKVTPGAASAAAGAKNG-YGDYLIEEEEGL 62

Query: 246 XXXXXXXXXXXXXXXXXXXXXXXPAAVARCAEIQNAISVGAXSFLFTQYKYLAAFTVIFA 425
                                     V +CAEIQ AIS GA SFLFT Y+Y+  F V+FA
Sbjct: 63  NDHN---------------------VVVKCAEIQTAISEGATSFLFTMYQYVGMFMVVFA 101

Query: 426 VVIFLFLGSVHRFSTASQPCQYTK 497
            +IFLFLGS+  FST  QPC Y+K
Sbjct: 102 AIIFLFLGSIEGFSTKGQPCTYSK 125

>HPPA2_RHOPA (Q8KY01) Pyrophosphate-energized proton pump (EC 3.6.1.1)|
           (Pyrophosphate-energized inorganic pyrophosphatase)
           (H+-PPase) (Membrane-bound proton-translocating
           pyrophosphatase)
          Length = 725

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 20/46 (43%), Positives = 27/46 (58%)
 Frame = +3

Query: 318 AAVARCAEIQNAISVGAXSFLFTQYKYLAAFTVIFAVVIFLFLGSV 455
           A  AR  EI  AI  GA ++L  QYK +A    + A++IF FLG +
Sbjct: 33  AGNARMQEIAGAIQQGAAAYLARQYKTIAIVGAVLAILIFFFLGGL 78

>HPPA_CLOTE (Q898Q9) Pyrophosphate-energized proton pump (EC 3.6.1.1)|
           (Pyrophosphate-energized inorganic pyrophosphatase)
           (H+-PPase) (Membrane-bound proton-translocating
           pyrophosphatase)
          Length = 673

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 19/40 (47%), Positives = 25/40 (62%)
 Frame = +3

Query: 330 RCAEIQNAISVGAXSFLFTQYKYLAAFTVIFAVVIFLFLG 449
           R  EI   I  GA +FL T+YKYL  F VI  V++ +F+G
Sbjct: 35  RMQEIAGHIHDGAMAFLKTEYKYLTGFIVIVTVILAIFVG 74

>HPPA_LEPIN (Q8F641) Pyrophosphate-energized proton pump (EC 3.6.1.1)|
           (Pyrophosphate-energized inorganic pyrophosphatase)
           (H+-PPase) (Membrane-bound proton-translocating
           pyrophosphatase)
          Length = 704

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 17/36 (47%), Positives = 23/36 (63%)
 Frame = +3

Query: 339 EIQNAISVGAXSFLFTQYKYLAAFTVIFAVVIFLFL 446
           EI +AIS GA +FL  +YK ++ F    AV+I L L
Sbjct: 45  EISSAISEGAMAFLVREYKVISLFIAFMAVLIVLLL 80

>HPPA_LEPIC (Q72Q29) Pyrophosphate-energized proton pump (EC 3.6.1.1)|
           (Pyrophosphate-energized inorganic pyrophosphatase)
           (H+-PPase) (Membrane-bound proton-translocating
           pyrophosphatase)
          Length = 704

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 17/36 (47%), Positives = 23/36 (63%)
 Frame = +3

Query: 339 EIQNAISVGAXSFLFTQYKYLAAFTVIFAVVIFLFL 446
           EI +AIS GA +FL  +YK ++ F    AV+I L L
Sbjct: 45  EISSAISEGAMAFLVREYKVISLFIAFMAVLIVLLL 80

>HPPA_PYRAE (Q8ZWI8) Pyrophosphate-energized proton pump (EC 3.6.1.1)|
           (Pyrophosphate-energized inorganic pyrophosphatase)
           (H+-PPase) (Membrane-bound proton-translocating
           pyrophosphatase)
          Length = 721

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 17/40 (42%), Positives = 24/40 (60%)
 Frame = +3

Query: 342 IQNAISVGAXSFLFTQYKYLAAFTVIFAVVIFLFLGSVHR 461
           I  AI+ GA ++LF QY+ LA   VI AV+I + +    R
Sbjct: 41  ISQAIATGARAYLFRQYRTLAVLLVILAVLILVAIDMPRR 80

>KLH21_HUMAN (Q9UJP4) Kelch-like protein 21|
          Length = 539

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 26/74 (35%), Positives = 29/74 (39%), Gaps = 12/74 (16%)
 Frame = -2

Query: 233 RPEHWPAVYAVAR----RRVGGHLHLGDKEPLPER--------EGNADHGARRYDRVGRG 90
           R  HWP +    R    RR     H+ + EPL  R            D  A RYDR  RG
Sbjct: 213 RAAHWPQLLEAVRLPFVRRFYLLAHV-EAEPLVARCPPCLRLLREARDFQAARYDRHDRG 271

Query: 89  EAHRARPREPAGKA 48
              R RPR   G A
Sbjct: 272 PCPRMRPRPSTGLA 285

>OPSG_GECGE (P35358) Green-sensitive opsin P521 (Green photoreceptor pigment)|
          Length = 365

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +3

Query: 6   TTCHISNPLSLSVSCFSRWFPGARAMGFSAADAVIPACAVIGIAFA-LWQW 155
           ++C I+   SL++  + RWF   +  G    D+ +   A+IGI F+ +W W
Sbjct: 133 SSCGITGLWSLAIISWERWFVVCKPFGNIKFDSKL---AIIGIVFSWVWAW 180

>PALST_EUGGR (P84739) Photoactivated adenylate cyclase alpha-subunit-like|
           protein ST-
          Length = 1019

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 2/54 (3%)
 Frame = -2

Query: 209 YAVARRRVGGHLHLGDKEPLPEREGNADH--GARRYDRVGRGEAHRARPREPAG 54
           Y   R  +G   H  D   +P R G   H  G RR+ R G G   R  P  P G
Sbjct: 787 YPGPRMGIGCANHQEDHLRVPRRPGPGRHEEGGRRHQRPGPGRPRRGHPFLPQG 840

>HAP1_MOUSE (O35668) Huntingtin-associated protein 1 (HAP-1)|
          Length = 628

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 13/29 (44%), Positives = 17/29 (58%)
 Frame = -2

Query: 128 DHGARRYDRVGRGEAHRARPREPAGKARH 42
           D+G+R  DR   G++HR R   PAG   H
Sbjct: 384 DYGSRPRDRQEDGKSHRQRSSMPAGSVTH 412

>COLI_MACNE (P01201) Corticotropin-lipotropin precursor (Pro-opiomelanocortin)|
           (POMC) [Contains: NPP; Melanotropin gamma (Gamma-MSH);
           Potential peptide; Corticotropin (Adrenocorticotropic
           hormone) (ACTH); Melanotropin alpha (Alpha-MSH);
           Corticotropin-like
          Length = 264

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 5/52 (9%)
 Frame = -2

Query: 167 GDKEPLPEREGNADHGARRYDRVGR-----GEAHRARPREPAGKARHGKREG 27
           GD++PL E       G  R+DR GR     G AH+ R    AG+ R    EG
Sbjct: 65  GDEQPLTENPRKYVMGHFRWDRFGRRNSSSGSAHQKREDVAAGEDRGLLPEG 116

>PXDC2_XENLA (Q6DE92) Plexin domain-containing protein 2 precursor|
          Length = 513

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 15/39 (38%), Positives = 21/39 (53%)
 Frame = -2

Query: 251 LTVLVLRPEHWPAVYAVARRRVGGHLHLGDKEPLPEREG 135
           L ++  RP  WPA+     RR  GH    + EP+ E+EG
Sbjct: 471 LFLIERRPSRWPAMKF---RRGSGHPAYAEVEPIGEKEG 506

>OPSR_ANOCA (P41592) Red-sensitive opsin (Red cone photoreceptor pigment)|
          Length = 369

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 20/53 (37%), Positives = 26/53 (49%)
 Frame = +3

Query: 6   TTCHISNPLSLSVSCFSRWFPGARAMGFSAADAVIPACAVIGIAFALWQWFLV 164
           +TC IS   SL+V  + RW    +  G    DA +   AV GI F+ W W  V
Sbjct: 137 STCGISALWSLAVISWERWVVVCKPFGNVKFDAKL---AVAGIVFS-WVWSAV 185

>ATG18_ASHGO (Q75F47) Autophagy-related protein 18|
          Length = 537

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 13/31 (41%), Positives = 18/31 (58%)
 Frame = +3

Query: 6   TTCHISNPLSLSVSCFSRWFPGARAMGFSAA 98
           T C I  PL+L +S +   F G+R M  SA+
Sbjct: 452 TICTIGEPLTLDISDYPELFSGSRTMAQSAS 482


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,237,192
Number of Sequences: 219361
Number of extensions: 992577
Number of successful extensions: 3357
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3246
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3355
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3523384522
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)