Clone Information

BLAST Search Result

Clone Name	baet91d04
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	IMA1B_ORYSA (Q9SLX0) Importin alpha-1b subunit	278	4e-75
2	IMA1A_ORYSA (Q71VM4) Importin alpha-1a subunit	261	8e-70
3	IMA1_ARATH (Q96321) Importin alpha-1 subunit (Karyopherin alpha-...	254	6e-68
4	IMA_LYCES (O22478) Importin alpha subunit (Karyopherin alpha sub...	251	5e-67
5	IMA2_ARATH (O04294) Importin alpha-2 subunit (Karyopherin alpha-...	237	1e-62
6	IMA5_HUMAN (O15131) Importin alpha-6 subunit (Karyopherin alpha-...	200	2e-51
7	IMA7_MOUSE (O35345) Importin alpha-7 subunit (Karyopherin alpha-...	200	2e-51
8	IMA7_HUMAN (O60684) Importin alpha-7 subunit (Karyopherin alpha-6)	199	4e-51
9	IMA1_SCHPO (O14063) Importin alpha subunit (Karyopherin alpha su...	194	7e-50
10	IMA1_HUMAN (P52294) Importin alpha-1 subunit (Karyopherin alpha-...	192	5e-49
11	IMA1_RAT (P83953) Importin alpha-1 subunit (Karyopherin alpha-1 ...	191	1e-48
12	IMA1_MOUSE (Q60960) Importin alpha-1 subunit (Karyopherin alpha-...	191	1e-48
13	IMA1_YEAST (Q02821) Importin alpha subunit (Karyopherin alpha su...	182	4e-46
14	IMA_DROME (P52295) Importin alpha subunit (Karyopherin alpha sub...	158	6e-39
15	IMA2_MOUSE (P52293) Importin alpha-2 subunit (Karyopherin alpha-...	157	1e-38
16	IMA1_XENLA (P52170) Importin alpha-1 subunit (Karyopherin alpha-...	155	5e-38
17	IMA2_HUMAN (P52292) Importin alpha-2 subunit (Karyopherin alpha-...	154	8e-38
18	IMA2_XENLA (P52171) Importin alpha-2 subunit (Karyopherin alpha-...	153	2e-37
19	IMA4_MOUSE (O35343) Importin alpha-4 subunit (Karyopherin alpha-...	150	2e-36
20	IMA4_HUMAN (O00629) Importin alpha-4 subunit (Karyopherin alpha-...	150	2e-36
21	IMA3_MOUSE (O35344) Importin alpha-3 subunit (Karyopherin alpha-...	144	1e-34
22	IMA3_HUMAN (O00505) Importin alpha-3 subunit (Karyopherin alpha-...	144	1e-34
23	IMA3_CAEEL (Q19969) Importin alpha-3 subunit (Karyopherin alpha-...	144	1e-34
24	IMA2_CAEEL (P91276) Importin alpha-2 subunit (Karyopherin alpha-...	130	2e-30
25	IMA2_ORYSA (Q9FYP9) Importin alpha-2 subunit	78	1e-14
26	SPAG6_MOUSE (Q9JLI7) Sperm-associated antigen 6 (PF16 protein ho...	45	1e-04
27	SPAG6_HUMAN (O75602) Sperm-associated antigen 6 (PF16 protein ho...	44	3e-04
28	IMA1_CAEEL (Q22560) Importin alpha-1 subunit (Karyopherin alpha-...	36	0.043
29	GDS1_BOVIN (Q04173) Rap1 GTPase-GDP dissociation stimulator 1 (S...	33	0.28
30	PUB14_ARATH (Q8VZ40) E3 ubiquitin ligase PUB14 (EC 6.3.2.-) (Pro...	33	0.36
31	GDS1A_XENLA (O93614) Rap1 GTPase-GDP dissociation stimulator 1-A...	33	0.36
32	PLAK_XENLA (P30998) Junction plakoglobin (Desmoplakin III)	32	0.62
33	IMB1_YEAST (Q06142) Importin beta-1 subunit (Karyopherin beta-1 ...	32	0.80
34	SEC6_YEAST (P32844) Exocyst complex component SEC6	32	1.0
35	IMB1_SCHPO (O13864) Importin beta-1 subunit (Karyopherin beta-1 ...	31	1.4
36	PSMR1_HALSA (Q9HNP9) Proteasome-activating nucleotidase 1 (Prote...	31	1.8
37	PLAK_HUMAN (P14923) Junction plakoglobin (Desmoplakin-3) (Desmop...	30	2.3
38	PLAK_RAT (Q6P0K8) Junction plakoglobin	30	2.3
39	PLAK_PIG (Q8WNW3) Junction plakoglobin	30	2.3
40	PLAK_MOUSE (Q02257) Junction plakoglobin (Desmoplakin-3) (Desmop...	30	2.3
41	PLAK_BOVIN (Q8SPJ1) Junction plakoglobin (Desmoplakin III)	30	2.3
42	YL112_MIMIV (Q5UPI6) Putative ankyrin repeat protein L112	30	2.3
43	DHE2_NEUCR (P00365) NAD-specific glutamate dehydrogenase (EC 1.4...	30	3.1
44	TAGH_LACLA (Q9CH26) Teichoic acids export ATP-binding protein ta...	30	4.0
45	AEP3_KLULA (Q6CIF3) ATPase expression protein 3	30	4.0
46	GCN2_YEAST (P15442) Serine/threonine-protein kinase GCN2 (EC 2.7...	30	4.0
47	NANA_STAAW (Q8NYC7) N-acetylneuraminate lyase (EC 4.1.3.3) (N-ac...	29	6.8
48	NANA_STAAS (Q6GCF6) N-acetylneuraminate lyase (EC 4.1.3.3) (N-ac...	29	6.8
49	NANA_STAAR (Q6GK01) N-acetylneuraminate lyase (EC 4.1.3.3) (N-ac...	29	6.8
50	NANA_STAAN (P99123) N-acetylneuraminate lyase (EC 4.1.3.3) (N-ac...	29	6.8
51	NANA_STAAM (P63949) N-acetylneuraminate lyase (EC 4.1.3.3) (N-ac...	29	6.8
52	NANA_STAAC (Q5HJ53) N-acetylneuraminate lyase (EC 4.1.3.3) (N-ac...	29	6.8
53	DEGP7_ARATH (Q8RY22) Protease Do-like 7 (EC 3.4.21.-)	28	8.9
54	SPA3N_MOUSE (Q91WP6) Serine protease inhibitor A3N precursor (Se...	28	8.9
55	VE2_HPV14 (P36783) Regulatory protein E2	28	8.9

>IMA1B_ORYSA (Q9SLX0) Importin alpha-1b subunit|
          Length = 534

 Score =  278 bits (712), Expect = 4e-75
 Identities = 139/149 (93%), Positives = 144/149 (96%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           HSQDEEVLTDACWALSYLSDGTNDKIQ+VIESGVFPRLVELL+HPSASVLIPALRTVGNI
Sbjct: 258 HSQDEEVLTDACWALSYLSDGTNDKIQAVIESGVFPRLVELLMHPSASVLIPALRTVGNI 317

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTGDD+QTQ VID+QALPCLLNLLT NHKKSIKKEACWTISNITAGNR+QIQAVI ANII
Sbjct: 318 VTGDDMQTQCVIDHQALPCLLNLLTNNHKKSIKKEACWTISNITAGNREQIQAVINANII 377

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
            PLVHLLQ AEFDIKKEAAWAISNATSGG
Sbjct: 378 APLVHLLQTAEFDIKKEAAWAISNATSGG 406



 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 44/143 (30%), Positives = 72/143 (50%), Gaps = 4/143 (2%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+D  + V+ESG  P  V+LL  PS  V   A+  +GN+         
Sbjct: 141 EAAWALTNIASGTSDNTKVVVESGAVPIFVKLLSSPSEDVREQAVWALGNVAGDSPKCRD 200

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAG----NRDQIQAVIQANIIGPLVH 375
            V+ +  L  LL  L  + K S+ + A WT+SN   G    N +Q++  + A     L  
Sbjct: 201 LVLASGGLYPLLQQLNEHAKLSMLRNATWTLSNFCRGKPQPNFEQVKPALSA-----LQR 255

Query: 376 LLQGAEFDIKKEAAWAISNATSG 444
           L+   + ++  +A WA+S  + G
Sbjct: 256 LIHSQDEEVLTDACWALSYLSDG 278

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>IMA1A_ORYSA (Q71VM4) Importin alpha-1a subunit|
          Length = 526

 Score =  261 bits (666), Expect = 8e-70
 Identities = 132/149 (88%), Positives = 139/149 (93%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           HS DEEVLTDACWALSYLSDGTNDKIQ+VIE+GV PRLVELLLHPS SVLIPALRTVGNI
Sbjct: 252 HSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNI 311

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTGDD QTQ +ID+QALPCLL+LLT N KKSIKKEACWTISNITAGN+DQIQAVI A II
Sbjct: 312 VTGDDAQTQCIIDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGII 371

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
           GPLV+LLQ AEFDIKKEAAWAISNATSGG
Sbjct: 372 GPLVNLLQTAEFDIKKEAAWAISNATSGG 400



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 53/192 (27%), Positives = 79/192 (41%), Gaps = 45/192 (23%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVI--ESGVFPRLVELLLHPSASVLIPALRTVGN 177
           S  ++V   A WAL  ++ G + K + ++     + P L +L  H   S+L  A  T+ N
Sbjct: 169 SSSDDVREQAVWALGNVA-GDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNATWTLSN 227

Query: 178 IVTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANI 357
              G   Q        ALP L  L+ +N ++ +  +ACW +S ++ G  D+IQAVI+A +
Sbjct: 228 FCRGKP-QPSFEQTRPALPALARLIHSNDEE-VLTDACWALSYLSDGTNDKIQAVIEAGV 285

Query: 358 IGPLVHLL-------------------------------------------QGAEFDIKK 408
              LV LL                                           Q  +  IKK
Sbjct: 286 CPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQCIIDHQALPCLLSLLTQNLKKSIKK 345

Query: 409 EAAWAISNATSG 444
           EA W ISN T+G
Sbjct: 346 EACWTISNITAG 357



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 41/139 (29%), Positives = 67/139 (48%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT++  + VI+ G  P  V+LL   S  V   A+  +GN+         
Sbjct: 135 EAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRD 194

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQG 387
            V+ N AL  LL  L  + K S+ + A WT+SN   G + Q         +  L  L+  
Sbjct: 195 LVLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRG-KPQPSFEQTRPALPALARLIHS 253

Query: 388 AEFDIKKEAAWAISNATSG 444
            + ++  +A WA+S  + G
Sbjct: 254 NDEEVLTDACWALSYLSDG 272



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 39/134 (29%), Positives = 69/134 (51%), Gaps = 3/134 (2%)
 Frame = +1

Query: 52  LSDGTNDKIQSVIESGVFPRLVELLLHPSASVL-IPALRTVGNIVTGDDLQTQ*VIDNQA 228
           LS   +  I+ VI+SGV PR V+ L       L   A   + NI +G    T+ VID+ A
Sbjct: 100 LSIERSPPIEEVIQSGVVPRFVQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGA 159

Query: 229 LPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQAN--IIGPLVHLLQGAEFDI 402
           +P  + LL ++    ++++A W + N+ AG+  + + ++ AN  ++  L  L +  +  +
Sbjct: 160 VPIFVKLLGSS-SDDVREQAVWALGNV-AGDSPKCRDLVLANGALLPLLAQLNEHTKLSM 217

Query: 403 KKEAAWAISNATSG 444
            + A W +SN   G
Sbjct: 218 LRNATWTLSNFCRG 231

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>IMA1_ARATH (Q96321) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)|
           (KAP alpha)
          Length = 532

 Score =  254 bits (650), Expect = 6e-68
 Identities = 126/149 (84%), Positives = 137/149 (91%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           HS DEEVLTDACWALSYLSDGTNDKIQ+VI++GV P+LVELLLH S SVLIPALRTVGNI
Sbjct: 252 HSDDEEVLTDACWALSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNI 311

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTGDD+QTQ VI++ ALPCL NLLT NHKKSIKKEACWTISNITAGN+DQIQ V++AN+I
Sbjct: 312 VTGDDIQTQCVINSGALPCLANLLTQNHKKSIKKEACWTISNITAGNKDQIQTVVEANLI 371

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
            PLV LLQ AEFDIKKEAAWAISNATSGG
Sbjct: 372 SPLVSLLQNAEFDIKKEAAWAISNATSGG 400



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 4/143 (2%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+D  + VI+    P  V+LL  PS  V   A+  +GN+         
Sbjct: 135 EAAWALTNIASGTSDHTKVVIDHNAVPIFVQLLASPSDDVREQAVWALGNVAGDSPRCRD 194

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAG----NRDQIQAVIQANIIGPLVH 375
            V+   AL  LLN L  + K S+ + A WT+SN   G    + DQ++  + A     L  
Sbjct: 195 LVLGCGALLPLLNQLNEHAKLSMLRNATWTLSNFCRGKPQPHFDQVKPALPA-----LER 249

Query: 376 LLQGAEFDIKKEAAWAISNATSG 444
           L+   + ++  +A WA+S  + G
Sbjct: 250 LIHSDDEEVLTDACWALSYLSDG 272



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
 Frame = +1

Query: 331 IQAVIQANIIGPLVHLLQGAEFD-IKKEAAWAISNATSG 444
           I+ VI A ++   V  L+  ++  I+ EAAWA++N  SG
Sbjct: 108 IEEVISAGVVPRFVEFLKKEDYPAIQFEAAWALTNIASG 146

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>IMA_LYCES (O22478) Importin alpha subunit (Karyopherin alpha subunit) (KAP|
           alpha)
          Length = 527

 Score =  251 bits (642), Expect = 5e-67
 Identities = 126/150 (84%), Positives = 138/150 (92%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           HS DEEVLTDACWALSYLSDGTNDKIQ+VIE+GV  RLVELLLH S SVLIPALRTVGNI
Sbjct: 253 HSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCSRLVELLLHSSPSVLIPALRTVGNI 312

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTGDD+QTQ +ID+ ALPCL+NLLT N+KKSIKKEACWTISNITAGNR+QIQ VI+A II
Sbjct: 313 VTGDDIQTQVMIDHHALPCLVNLLTQNYKKSIKKEACWTISNITAGNRNQIQIVIEAGII 372

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGGH 450
            PLV+LLQ AEF+IKKEAAWAISNATSGG+
Sbjct: 373 APLVYLLQNAEFEIKKEAAWAISNATSGGN 402



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 2/141 (1%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT++  + VI+ G  P  + LL  PS  V   A+  +GNI         
Sbjct: 136 EAAWALTNIASGTSENTKVVIDYGSVPIFIRLLSSPSDDVREQAVWALGNIAGDSPKYRD 195

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANI--IGPLVHLL 381
            V+ + AL  LL       K S+ + A WT+SN   G    +    +A +  +G L+H  
Sbjct: 196 LVLGHGALVALLAQFNEQAKLSMLRNATWTLSNFCRGKPQPLFEQTKAALPTLGRLIH-- 253

Query: 382 QGAEFDIKKEAAWAISNATSG 444
              + ++  +A WA+S  + G
Sbjct: 254 -SNDEEVLTDACWALSYLSDG 273



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 43/136 (31%), Positives = 69/136 (50%), Gaps = 5/136 (3%)
 Frame = +1

Query: 52  LSDGTNDKIQSVIESGVFPRLVELLLHPSASVL-IPALRTVGNIVTGDDLQTQ*VIDNQA 228
           LS   N  I+ VI+SGV PR VE L       L   A   + NI +G    T+ VID  +
Sbjct: 101 LSIERNPPIEEVIQSGVVPRFVEFLARDDYPQLQFEAAWALTNIASGTSENTKVVIDYGS 160

Query: 229 LPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLL----QGAEF 396
           +P  + LL ++    ++++A W + NI AG+  + + ++  +  G LV LL    + A+ 
Sbjct: 161 VPIFIRLL-SSPSDDVREQAVWALGNI-AGDSPKYRDLVLGH--GALVALLAQFNEQAKL 216

Query: 397 DIKKEAAWAISNATSG 444
            + + A W +SN   G
Sbjct: 217 SMLRNATWTLSNFCRG 232

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>IMA2_ARATH (O04294) Importin alpha-2 subunit (Karyopherin alpha-2 subunit)|
           (KAP alpha)
          Length = 531

 Score =  237 bits (604), Expect = 1e-62
 Identities = 119/148 (80%), Positives = 130/148 (87%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           S DEEVLTDACWALSYLSD +NDKIQ+VIE+GV PRL++LL H S SVLIPALRT+GNIV
Sbjct: 256 SMDEEVLTDACWALSYLSDNSNDKIQAVIEAGVVPRLIQLLGHSSPSVLIPALRTIGNIV 315

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIG 363
           TGDDLQTQ V+D QALPCLLNLL  N+KKSIKKEACWTISNITAGN DQIQAVI A II 
Sbjct: 316 TGDDLQTQMVLDQQALPCLLNLLKNNYKKSIKKEACWTISNITAGNADQIQAVIDAGIIQ 375

Query: 364 PLVHLLQGAEFDIKKEAAWAISNATSGG 447
            LV +LQ AEF++KKEAAW ISNATSGG
Sbjct: 376 SLVWVLQSAEFEVKKEAAWGISNATSGG 403



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 40/138 (28%), Positives = 66/138 (47%), Gaps = 4/138 (2%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT++    +IESG  P  ++LL   S  V   A+  +GN+         
Sbjct: 138 EAAWALTNIASGTSENTNVIIESGAVPIFIQLLSSASEDVREQAVWALGNVAGDSPKCRD 197

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNR----DQIQAVIQANIIGPLVH 375
            V+   A+  LL+    N K S+ + A WT+SN   G      +Q Q  +       L  
Sbjct: 198 LVLSYGAMTPLLSQFNENTKLSMLRNATWTLSNFCRGKPPPAFEQTQPALPV-----LER 252

Query: 376 LLQGAEFDIKKEAAWAIS 429
           L+Q  + ++  +A WA+S
Sbjct: 253 LVQSMDEEVLTDACWALS 270



 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 2/133 (1%)
 Frame = +1

Query: 52  LSDGTNDKIQSVIESGVFPRLVELLLHPSASVL-IPALRTVGNIVTGDDLQTQ*VIDNQA 228
           LS   N  I  V++SGV PR+V+ L       L   A   + NI +G    T  +I++ A
Sbjct: 103 LSIEQNPPINEVVQSGVVPRVVKFLSRDDFPKLQFEAAWALTNIASGTSENTNVIIESGA 162

Query: 229 LPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLV-HLLQGAEFDIK 405
           +P  + LL ++  + ++++A W + N+   +      V+    + PL+    +  +  + 
Sbjct: 163 VPIFIQLL-SSASEDVREQAVWALGNVAGDSPKCRDLVLSYGAMTPLLSQFNENTKLSML 221

Query: 406 KEAAWAISNATSG 444
           + A W +SN   G
Sbjct: 222 RNATWTLSNFCRG 234

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>IMA5_HUMAN (O15131) Importin alpha-6 subunit (Karyopherin alpha-5 subunit)|
          Length = 536

 Score =  200 bits (508), Expect = 2e-51
 Identities = 102/148 (68%), Positives = 121/148 (81%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           S D +VL D CWALSYLSDG NDKIQ+VI+SGV  RLVELL+H    V+ PALR VGNIV
Sbjct: 263 SSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIV 322

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIG 363
           TGDD+QTQ +++  ALPCLL+LL ++ K+SI+KEACWT+SNITAGNR QIQAVI ANI  
Sbjct: 323 TGDDIQTQVILNCSALPCLLHLL-SSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFP 381

Query: 364 PLVHLLQGAEFDIKKEAAWAISNATSGG 447
            L+ +LQ AEF  +KEAAWAI+NATSGG
Sbjct: 382 VLIEILQKAEFRTRKEAAWAITNATSGG 409



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 41/140 (29%), Positives = 72/140 (51%), Gaps = 1/140 (0%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT    + VIE+G  P  ++LL      V   A+  +GNI  GD+ + +
Sbjct: 144 EAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNI-AGDNAECR 202

Query: 208 -*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQ 384
             V++ + LP LL LLT +++ +  + A W +SN+  G          +  +  L  LL 
Sbjct: 203 DFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLF 262

Query: 385 GAEFDIKKEAAWAISNATSG 444
            ++ D+  +  WA+S  + G
Sbjct: 263 SSDPDVLADVCWALSYLSDG 282

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>IMA7_MOUSE (O35345) Importin alpha-7 subunit (Karyopherin alpha-6 subunit)|
           (Importin alpha S2)
          Length = 533

 Score =  200 bits (508), Expect = 2e-51
 Identities = 102/148 (68%), Positives = 122/148 (82%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           S D ++L DACWALSYLSDG N+KIQ+VI+SGV  RLVELL+H    V  PALR VGNIV
Sbjct: 260 SSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIV 319

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIG 363
           TGDD+QTQ +++  ALPCLL+LL+++ K+SI+KEACWTISNITAGNR QIQAVI ANI  
Sbjct: 320 TGDDIQTQVILNCSALPCLLHLLSSS-KESIRKEACWTISNITAGNRAQIQAVIDANIFP 378

Query: 364 PLVHLLQGAEFDIKKEAAWAISNATSGG 447
            L+ +LQ AEF  +KEAAWAI+NATSGG
Sbjct: 379 VLIEILQKAEFRTRKEAAWAITNATSGG 406



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 41/139 (29%), Positives = 70/139 (50%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+ + + VIE+G  P  +ELL      V   A+  +GNI     L   
Sbjct: 141 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSLCRD 200

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQG 387
            V++   L  LL LLT + + ++ + A W +SN+  G     +    +  +  L  LL  
Sbjct: 201 YVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFS 260

Query: 388 AEFDIKKEAAWAISNATSG 444
           ++ D+  +A WA+S  + G
Sbjct: 261 SDSDLLADACWALSYLSDG 279

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>IMA7_HUMAN (O60684) Importin alpha-7 subunit (Karyopherin alpha-6)|
          Length = 536

 Score =  199 bits (505), Expect = 4e-51
 Identities = 102/148 (68%), Positives = 121/148 (81%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           S D ++L DACWALSYLSDG N+KIQ+VI+SGV  RLVELL+H    V  PALR VGNIV
Sbjct: 263 SSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIV 322

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIG 363
           TGDD+QTQ +++  ALPCLL+LL ++ K+SI+KEACWTISNITAGNR QIQAVI ANI  
Sbjct: 323 TGDDIQTQVILNCSALPCLLHLL-SSPKESIRKEACWTISNITAGNRAQIQAVIDANIFP 381

Query: 364 PLVHLLQGAEFDIKKEAAWAISNATSGG 447
            L+ +LQ AEF  +KEAAWAI+NATSGG
Sbjct: 382 VLIEILQKAEFRTRKEAAWAITNATSGG 409



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 40/139 (28%), Positives = 70/139 (50%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+ + + VIE+G  P  +ELL      V   A+  +GNI     +   
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRD 203

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQG 387
            V++   L  LL LLT + + ++ + A W +SN+  G     +    +  +  L  LL  
Sbjct: 204 YVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFS 263

Query: 388 AEFDIKKEAAWAISNATSG 444
           ++ D+  +A WA+S  + G
Sbjct: 264 SDSDLLADACWALSYLSDG 282

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>IMA1_SCHPO (O14063) Importin alpha subunit (Karyopherin alpha subunit)|
           (Serine-rich RNA polymerase I suppressor protein) (Cell
           untimely torn protein 15)
          Length = 542

 Score =  194 bits (494), Expect = 7e-50
 Identities = 98/149 (65%), Positives = 123/149 (82%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           ++ DE+VL DA WA+SYLSDG N+KIQ++I++G+  RLVELL+HPSA V  PALR+VGNI
Sbjct: 258 YTLDEDVLVDALWAISYLSDGANEKIQAIIDAGIPRRLVELLMHPSAQVQTPALRSVGNI 317

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTGDD+QTQ +I+  AL  LL+LL ++ +  ++KEACWTISNITAGN  QIQ VI+ANII
Sbjct: 318 VTGDDVQTQVIINCGALSALLSLL-SSPRDGVRKEACWTISNITAGNSSQIQYVIEANII 376

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
            PL+HLL  A+F I+KEA WAISNATSGG
Sbjct: 377 PPLIHLLTTADFKIQKEACWAISNATSGG 405



 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 39/141 (27%), Positives = 70/141 (49%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ G++++   V+E+   P  V LL      V   A+  +GNI     +   
Sbjct: 140 EASWALTNVASGSSNQTHVVVEANAVPVFVSLLSSSEQDVREQAVWALGNIAGDSPMCRD 199

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQG 387
            V+    L  LLN++ +N + S+ + + WT+SN+  G   Q      + +I  L  L+  
Sbjct: 200 HVLQCGVLEPLLNIIESNRRLSMLRNSTWTLSNMCRGKNPQPDWNSISQVIPVLSKLIYT 259

Query: 388 AEFDIKKEAAWAISNATSGGH 450
            + D+  +A WAIS  + G +
Sbjct: 260 LDEDVLVDALWAISYLSDGAN 280



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 40/136 (29%), Positives = 58/136 (42%)
 Frame = +1

Query: 52  LSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ*VIDNQAL 231
           LS  TN  IQ VI++GV PR VE L H +                               
Sbjct: 106 LSKETNPPIQKVIDAGVVPRFVEFLSHEN------------------------------- 134

Query: 232 PCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGAEFDIKKE 411
               NLL        K EA W ++N+ +G+ +Q   V++AN +   V LL  +E D++++
Sbjct: 135 ----NLL--------KFEASWALTNVASGSSNQTHVVVEANAVPVFVSLLSSSEQDVREQ 182

Query: 412 AAWAISNATSGGHMIR 459
           A WA+ N      M R
Sbjct: 183 AVWALGNIAGDSPMCR 198

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>IMA1_HUMAN (P52294) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)|
           (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein
           interactor 1) (NPI-1)
          Length = 538

 Score =  192 bits (487), Expect = 5e-49
 Identities = 100/146 (68%), Positives = 118/146 (80%)
 Frame = +1

Query: 10  DEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTG 189
           D +VL DACWALSYLSDG NDKIQ+VI++GV  RLVELL+H    V+ PALR VGNIVTG
Sbjct: 267 DTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 326

Query: 190 DDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPL 369
           DD+QTQ +++  AL  LL+LL ++ K+SIKKEACWTISNITAGNR QIQ VI ANI   L
Sbjct: 327 DDIQTQVILNCSALQSLLHLL-SSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPAL 385

Query: 370 VHLLQGAEFDIKKEAAWAISNATSGG 447
           + +LQ AEF  +KEAAWAI+NATSGG
Sbjct: 386 ISILQTAEFRTRKEAAWAITNATSGG 411



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 36/139 (25%), Positives = 68/139 (48%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           ++ W L+ ++ G + + + VI++G  P  +ELL      V   A+  +GNI     +   
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD 205

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQG 387
            V+D   LP LL L +  ++ ++ + A W +SN+  G     +    +  +  L  LL  
Sbjct: 206 YVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFV 265

Query: 388 AEFDIKKEAAWAISNATSG 444
           ++ D+  +A WA+S  + G
Sbjct: 266 SDTDVLADACWALSYLSDG 284



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 20/63 (31%), Positives = 35/63 (55%)
 Frame = +1

Query: 271 SIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGAEFDIKKEAAWAISNATSGGH 450
           +++ E+ W ++NI +GN  Q + VIQA  +   + LL     D++++A WA+ N      
Sbjct: 142 TLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDST 201

Query: 451 MIR 459
           M R
Sbjct: 202 MCR 204



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 1/144 (0%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           S  E +  +ACW +S ++ G   +IQ+VI++ +FP L+ +                    
Sbjct: 349 SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISI-------------------- 388

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITA-GNRDQIQAVIQANII 360
               LQT                    +   +KEA W I+N T+ G+ +QI+ +++   I
Sbjct: 389 ----LQTA-------------------EFRTRKEAAWAITNATSGGSAEQIKYLVELGCI 425

Query: 361 GPLVHLLQGAEFDIKKEAAWAISN 432
            PL  LL   +  I + A   + N
Sbjct: 426 KPLCDLLTVMDSKIVQVALNGLEN 449

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>IMA1_RAT (P83953) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)|
           (Importin alpha 5)
          Length = 538

 Score =  191 bits (484), Expect = 1e-48
 Identities = 99/146 (67%), Positives = 118/146 (80%)
 Frame = +1

Query: 10  DEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTG 189
           D +VL DACWALSYLSDG NDKIQ+VI++GV  RLVELL+H    V+ PALR VGNIVTG
Sbjct: 267 DTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 326

Query: 190 DDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPL 369
           DD+QTQ +++  AL  LL+LL ++ K+SIKKEACWTISNITAGNR QIQ VI AN+   L
Sbjct: 327 DDIQTQVILNCSALQSLLHLL-SSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPAL 385

Query: 370 VHLLQGAEFDIKKEAAWAISNATSGG 447
           + +LQ AEF  +KEAAWAI+NATSGG
Sbjct: 386 ISILQTAEFRTRKEAAWAITNATSGG 411



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 36/139 (25%), Positives = 68/139 (48%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           ++ W L+ ++ G + + + VI++G  P  +ELL      V   A+  +GNI     +   
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD 205

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQG 387
            V+D   LP LL L +  ++ ++ + A W +SN+  G     +    +  +  L  LL  
Sbjct: 206 YVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFV 265

Query: 388 AEFDIKKEAAWAISNATSG 444
           ++ D+  +A WA+S  + G
Sbjct: 266 SDTDVLADACWALSYLSDG 284



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 20/63 (31%), Positives = 35/63 (55%)
 Frame = +1

Query: 271 SIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGAEFDIKKEAAWAISNATSGGH 450
           +++ E+ W ++NI +GN  Q + VIQA  +   + LL     D++++A WA+ N      
Sbjct: 142 TLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDST 201

Query: 451 MIR 459
           M R
Sbjct: 202 MCR 204



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 1/144 (0%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           S  E +  +ACW +S ++ G   +IQ+VI++ +FP L+ +                    
Sbjct: 349 SPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISI-------------------- 388

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITA-GNRDQIQAVIQANII 360
               LQT                    +   +KEA W I+N T+ G+ +QI+ +++   I
Sbjct: 389 ----LQTA-------------------EFRTRKEAAWAITNATSGGSAEQIKYLVELGCI 425

Query: 361 GPLVHLLQGAEFDIKKEAAWAISN 432
            PL  LL   +  I + A   + N
Sbjct: 426 KPLCDLLTVMDAKIVQVALNGLEN 449

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>IMA1_MOUSE (Q60960) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)|
           (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein
           interactor 1) (Importin alpha S1)
          Length = 538

 Score =  191 bits (484), Expect = 1e-48
 Identities = 99/146 (67%), Positives = 118/146 (80%)
 Frame = +1

Query: 10  DEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTG 189
           D +VL DACWALSYLSDG NDKIQ+VI++GV  RLVELL+H    V+ PALR VGNIVTG
Sbjct: 267 DTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 326

Query: 190 DDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPL 369
           DD+QTQ +++  AL  LL+LL ++ K+SIKKEACWTISNITAGNR QIQ VI AN+   L
Sbjct: 327 DDIQTQVILNCSALQSLLHLL-SSPKESIKKEACWTISNITAGNRAQIQTVIDANMFPAL 385

Query: 370 VHLLQGAEFDIKKEAAWAISNATSGG 447
           + +LQ AEF  +KEAAWAI+NATSGG
Sbjct: 386 ISILQTAEFRTRKEAAWAITNATSGG 411



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 35/139 (25%), Positives = 69/139 (49%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           ++ W L+ ++ G + + ++VI++G  P  +ELL      V   A+  +GNI     +   
Sbjct: 146 ESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD 205

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQG 387
            V++   LP LL L +  ++ ++ + A W +SN+  G     +    +  +  L  LL  
Sbjct: 206 YVLNCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFV 265

Query: 388 AEFDIKKEAAWAISNATSG 444
           ++ D+  +A WA+S  + G
Sbjct: 266 SDTDVLADACWALSYLSDG 284



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 20/63 (31%), Positives = 35/63 (55%)
 Frame = +1

Query: 271 SIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGAEFDIKKEAAWAISNATSGGH 450
           +++ E+ W ++NI +GN  Q + VIQA  +   + LL     D++++A WA+ N      
Sbjct: 142 TLQFESAWVLTNIASGNSLQTRNVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDST 201

Query: 451 MIR 459
           M R
Sbjct: 202 MCR 204



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 1/144 (0%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           S  E +  +ACW +S ++ G   +IQ+VI++ +FP L+ +                    
Sbjct: 349 SPKESIKKEACWTISNITAGNRAQIQTVIDANMFPALISI-------------------- 388

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITA-GNRDQIQAVIQANII 360
               LQT                    +   +KEA W I+N T+ G+ +QI+ +++   I
Sbjct: 389 ----LQTA-------------------EFRTRKEAAWAITNATSGGSAEQIKYLVELGCI 425

Query: 361 GPLVHLLQGAEFDIKKEAAWAISN 432
            PL  LL   +  I + A   + N
Sbjct: 426 KPLCDLLTVMDAKIVQVALNGLEN 449

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>IMA1_YEAST (Q02821) Importin alpha subunit (Karyopherin alpha subunit)|
           (Serine-rich RNA polymerase I suppressor protein)
          Length = 542

 Score =  182 bits (462), Expect = 4e-46
 Identities = 97/149 (65%), Positives = 114/149 (76%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           +S D E L DACWA+SYLSDG  + IQ+VI+  +  RLVELL H S  V  PALR VGNI
Sbjct: 267 YSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNI 326

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTG+DLQTQ VI+   LP L  LL ++ K++IKKEACWTISNITAGN +QIQAVI AN+I
Sbjct: 327 VTGNDLQTQVVINAGVLPAL-RLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLI 385

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
            PLV LL+ AE+  KKEA WAISNA+SGG
Sbjct: 386 PPLVKLLEVAEYKTKKEACWAISNASSGG 414



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 39/147 (26%), Positives = 73/147 (49%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           +Q E +  +A WAL+ ++ GT+ + + V+++   P  ++LL   S  V   A+  +GN+ 
Sbjct: 142 NQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVA 201

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIG 363
                    V+   A+  +L L  +N K S+ + A WT+SN+  G + Q    + +  + 
Sbjct: 202 GDSTDYRDYVLQCNAMEPILGLFNSN-KPSLIRTATWTLSNLCRGKKPQPDWSVVSQALP 260

Query: 364 PLVHLLQGAEFDIKKEAAWAISNATSG 444
            L  L+   + +   +A WAIS  + G
Sbjct: 261 TLAKLIYSMDTETLVDACWAISYLSDG 287



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 41/146 (28%), Positives = 69/146 (47%)
 Frame = +1

Query: 16  EVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDD 195
           EV   A WAL  ++  + D    V++      ++ L      S++  A  T+ N+  G  
Sbjct: 188 EVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKK 247

Query: 196 LQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVH 375
            Q    + +QALP L  L+ +   +++  +ACW IS ++ G ++ IQAVI   I   LV 
Sbjct: 248 PQPDWSVVSQALPTLAKLIYSMDTETLV-DACWAISYLSDGPQEAIQAVIDVRIPKRLVE 306

Query: 376 LLQGAEFDIKKEAAWAISNATSGGHM 453
           LL      ++  A  A+ N  +G  +
Sbjct: 307 LLSHESTLVQTPALRAVGNIVTGNDL 332

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>IMA_DROME (P52295) Importin alpha subunit (Karyopherin alpha subunit)|
           (Pendulin)
          Length = 522

 Score =  158 bits (400), Expect = 6e-39
 Identities = 83/148 (56%), Positives = 107/148 (72%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           SQD +VL DACWALSY++D  N KIQ+V++S   PRLV+LL     S+++PALR+VGNIV
Sbjct: 251 SQDIQVLADACWALSYVTDDDNTKIQAVVDSDAVPRLVKLLQMDEPSIIVPALRSVGNIV 310

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIG 363
           TG D QT  VI +  LP  L LL  ++K +I KEA WT+SNITAGN+ QIQAVIQA I  
Sbjct: 311 TGTDQQTDVVIASGGLP-RLGLLLQHNKSNIVKEAAWTVSNITAGNQKQIQAVIQAGIFQ 369

Query: 364 PLVHLLQGAEFDIKKEAAWAISNATSGG 447
            L  +L+  +F  +KEAAWA++N T+ G
Sbjct: 370 QLRTVLEKGDFKAQKEAAWAVTNTTTSG 397



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 35/137 (25%), Positives = 59/137 (43%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+D+ + VIE    P  V LL   S ++   A+  +GNI         
Sbjct: 132 EAAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSKSMNLAEQAVWALGNIAGDGAAARD 191

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQG 387
            VI +  +  +L L+      S  +   W +SN+               ++  L  LL  
Sbjct: 192 IVIHHNVIDGILPLINNETPLSFLRNIVWLMSNLCRNKNPSPPFDQVKRLLPVLSQLLLS 251

Query: 388 AEFDIKKEAAWAISNAT 438
            +  +  +A WA+S  T
Sbjct: 252 QDIQVLADACWALSYVT 268



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 24/83 (28%), Positives = 42/83 (50%)
 Frame = +1

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           +I +  +P  +  L   +   ++ EA W ++NI +G  DQ + VI+ N +   V LLQ  
Sbjct: 108 MIGHGIVPICIRFLQNTNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSK 167

Query: 391 EFDIKKEAAWAISNATSGGHMIR 459
             ++ ++A WA+ N    G   R
Sbjct: 168 SMNLAEQAVWALGNIAGDGAAAR 190

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>IMA2_MOUSE (P52293) Importin alpha-2 subunit (Karyopherin alpha-2 subunit)|
           (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore
           targeting complex 58 kDa subunit) (PTAC58) (Importin
           alpha P1)
          Length = 529

 Score =  157 bits (398), Expect = 1e-38
 Identities = 82/149 (55%), Positives = 107/149 (71%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           H  D EVL D+CWA+SYL+DG N++I+ V++ GV P+LV+LL      ++ PALR +GNI
Sbjct: 261 HHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNI 320

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTG D QTQ VID  AL    +LL TN K +I+KEA WT+SNITAG +DQIQ V+   ++
Sbjct: 321 VTGTDEQTQKVIDAGALAVFPSLL-TNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV 379

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
             LV +L  A+F  +KEAAWAI+N TSGG
Sbjct: 380 PFLVGVLSKADFKTQKEAAWAITNYTSGG 408



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 38/143 (26%), Positives = 67/143 (46%), Gaps = 4/143 (2%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           ++ WAL+ ++ GT+++ ++V++ G  P  + LL  P A +   A+  +GNI         
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRD 198

Query: 208 *VIDNQALPCLLNLLTTNHKKSIK----KEACWTISNITAGNRDQIQAVIQANIIGPLVH 375
            VI + A+  LL LL      ++     +   WT+SN+               I+  LV 
Sbjct: 199 LVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVR 258

Query: 376 LLQGAEFDIKKEAAWAISNATSG 444
           LL   + ++  ++ WAIS  T G
Sbjct: 259 LLHHNDPEVLADSCWAISYLTDG 281

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>IMA1_XENLA (P52170) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)|
          Length = 521

 Score =  155 bits (392), Expect = 5e-38
 Identities = 76/149 (51%), Positives = 103/149 (69%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           H  D+++L+D CWA+SYL+DG+ND+I  V+++G+  RL++L+  P  S++ P+LRTVGNI
Sbjct: 253 HHDDKDILSDTCWAMSYLTDGSNDRIDVVVKTGIVDRLIQLMYSPELSIVTPSLRTVGNI 312

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTG D QTQ  ID   L  L  LL  + K SI+KEA W ISNI AG   QIQ +I   ++
Sbjct: 313 VTGTDKQTQAAIDAGVLSVLPQLL-RHQKPSIQKEAAWAISNIAAGPAPQIQQMITCGLL 371

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
            PLV LL   +F  +KEA WA++N TSGG
Sbjct: 372 SPLVDLLNKGDFKAQKEAVWAVTNYTSGG 400



 Score = 65.1 bits (157), Expect = 9e-11
 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 2/143 (1%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+D+ +SV++ G  P  + L+  P   +   A+  +GNI     L   
Sbjct: 135 EAAWALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPLYRD 194

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNR--DQIQAVIQANIIGPLVHLL 381
            +I+   +P LL L+         +   W +SN+         + AV+Q  I+  L  L+
Sbjct: 195 ALINCNVIPPLLALVNPQTPLGYLRNITWMLSNLCRNKNPYPPMSAVLQ--ILPVLTQLM 252

Query: 382 QGAEFDIKKEAAWAISNATSGGH 450
              + DI  +  WA+S  T G +
Sbjct: 253 HHDDKDILSDTCWAMSYLTDGSN 275



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 40/133 (30%), Positives = 68/133 (51%), Gaps = 2/133 (1%)
 Frame = +1

Query: 40  ALSYLSDGTNDKIQSVIESGVFPRLVELLL-HPSASVLIPALRTVGNIVTGDDLQTQ*VI 216
           A   LS   N  +  +IE+G+ P+LVE L  H ++++   A   + NI +G   QT+ V+
Sbjct: 96  ARKMLSRERNPPLNDIIEAGLIPKLVEFLSRHDNSTLQFEAAWALTNIASGTSDQTKSVV 155

Query: 217 DNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQ-GAE 393
           D  A+P  ++L+++ H   I ++A W + NI         A+I  N+I PL+ L+     
Sbjct: 156 DGGAIPAFISLISSPH-LHISEQAVWALGNIAGDGPLYRDALINCNVIPPLLALVNPQTP 214

Query: 394 FDIKKEAAWAISN 432
               +   W +SN
Sbjct: 215 LGYLRNITWMLSN 227

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>IMA2_HUMAN (P52292) Importin alpha-2 subunit (Karyopherin alpha-2 subunit)|
           (SRP1-alpha) (RAG cohort protein 1)
          Length = 529

 Score =  154 bits (390), Expect = 8e-38
 Identities = 80/149 (53%), Positives = 105/149 (70%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           H  D EVL D CWA+SYL+DG N++I  V+++GV P+LV+LL      ++ PALR +GNI
Sbjct: 261 HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNI 320

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTG D QTQ VID  AL    +LL TN K +I+KEA WT+SNITAG +DQIQ V+   ++
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLL-TNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV 379

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
             LV +L  A+F  +KEA WA++N TSGG
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTNYTSGG 408



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 39/143 (27%), Positives = 66/143 (46%), Gaps = 4/143 (2%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           ++ WAL+ ++ GT+++ ++V++ G  P  + LL  P A +   A+  +GNI     +   
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRD 198

Query: 208 *VIDNQALPCLLNLLTTNHKKSIK----KEACWTISNITAGNRDQIQAVIQANIIGPLVH 375
            VI   A+  LL LL      S+     +   WT+SN+               I+  LV 
Sbjct: 199 LVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVR 258

Query: 376 LLQGAEFDIKKEAAWAISNATSG 444
           LL   + ++  +  WAIS  T G
Sbjct: 259 LLHHDDPEVLADTCWAISYLTDG 281

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>IMA2_XENLA (P52171) Importin alpha-2 subunit (Karyopherin alpha-2 subunit)|
          Length = 522

 Score =  153 bits (387), Expect = 2e-37
 Identities = 75/147 (51%), Positives = 104/147 (70%)
 Frame = +1

Query: 7   QDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVT 186
           +D+++L+D CWA+SYL+DG+ND+I  V+++G+  RL++L+  P  S+L P+LRTVGNIVT
Sbjct: 255 EDKDILSDTCWAMSYLTDGSNDRIDVVVKTGLVERLIQLMYSPELSILTPSLRTVGNIVT 314

Query: 187 GDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGP 366
           G D QTQ  ID   L  L  LL  + K SI+KEA W +SNI AG   QIQ +I   ++ P
Sbjct: 315 GTDKQTQAAIDAGVLSVLPQLL-RHQKPSIQKEAAWALSNIAAGPAPQIQQMITCGLLSP 373

Query: 367 LVHLLQGAEFDIKKEAAWAISNATSGG 447
           LV LL+  +F  +KEA WA++N TSGG
Sbjct: 374 LVDLLKKGDFKAQKEAVWAVTNYTSGG 400



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 40/143 (27%), Positives = 68/143 (47%), Gaps = 2/143 (1%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+D+ +SV++ G  P  + L+  P   +   A+  +GNI     L   
Sbjct: 135 EAAWALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPLYRD 194

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNR--DQIQAVIQANIIGPLVHLL 381
            +I    +P LL L+         +   WT+SN+         + AV+Q  I+  L  L+
Sbjct: 195 ALISCNVIPPLLTLVNPQTPLGYLRNITWTLSNLCRNKNPYPPMSAVLQ--ILPVLTQLM 252

Query: 382 QGAEFDIKKEAAWAISNATSGGH 450
              + DI  +  WA+S  T G +
Sbjct: 253 LHEDKDILSDTCWAMSYLTDGSN 275



 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 2/143 (1%)
 Frame = +1

Query: 10  DEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELL-LHPSASVLIPALRTVGNIVT 186
           +E  L     A   LS   N  +  +IE+G+ P+LVE L  H ++++   A   + NI +
Sbjct: 86  NENELRSTQAARKMLSKERNPPLNDIIEAGLIPKLVEFLSYHNNSTLQFEAAWALTNIAS 145

Query: 187 GDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGP 366
           G   QT+ V+D  A+P  ++L+++ H   I ++A W + NI         A+I  N+I P
Sbjct: 146 GTSDQTKSVVDGGAIPAFISLISSPH-LHISEQAVWALGNIAGDGPLYRDALISCNVIPP 204

Query: 367 LVHLLQ-GAEFDIKKEAAWAISN 432
           L+ L+         +   W +SN
Sbjct: 205 LLTLVNPQTPLGYLRNITWTLSN 227

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>IMA4_MOUSE (O35343) Importin alpha-4 subunit (Karyopherin alpha-4 subunit)|
           (Importin alpha Q1)
          Length = 521

 Score =  150 bits (378), Expect = 2e-36
 Identities = 80/149 (53%), Positives = 99/149 (66%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           H  D  +L D  WALSYL+D  N++IQ VI+SG+ P LV LL H    V   ALR VGNI
Sbjct: 252 HHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNI 311

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTG D QTQ V++  AL     LL T+ K+ I KEA W +SNITAGN+ Q+QAVI AN++
Sbjct: 312 VTGTDEQTQVVLNCDALSHFPALL-THPKEKINKEAVWFLSNITAGNQQQVQAVIDANLV 370

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
             ++HLL   +F  +KEAAWAISN T  G
Sbjct: 371 PMIIHLLDKGDFGTQKEAAWAISNLTISG 399



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 26/83 (31%), Positives = 46/83 (55%)
 Frame = +1

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           +I +  LP L++ L  +   S++ EA W ++NI +G  +Q QAV+Q+N +   + LL   
Sbjct: 110 LIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSP 169

Query: 391 EFDIKKEAAWAISNATSGGHMIR 459
             ++ ++A WA+ N    G   R
Sbjct: 170 HQNVCEQAVWALGNIIGDGPQCR 192



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 2/133 (1%)
 Frame = +1

Query: 40  ALSYLSDGTNDKIQSVIESGVFPRLVELLLHP-SASVLIPALRTVGNIVTGDDLQTQ*VI 216
           A   LS   N  I  +I+SG+ P LV  L    + S+   A   + NI +G   QTQ V+
Sbjct: 95  ARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVV 154

Query: 217 DNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQ-GAE 393
            + A+P  L LL + H +++ ++A W + NI          VI   ++ PL+  +     
Sbjct: 155 QSNAVPLFLRLLHSPH-QNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIP 213

Query: 394 FDIKKEAAWAISN 432
               +   W + N
Sbjct: 214 ITFLRNVTWVMVN 226



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 42/181 (23%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+++ Q+V++S   P  + LL  P  +V   A+  +GNI+        
Sbjct: 134 EAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRD 193

Query: 208 *VIDNQALPCLLNLLTTN------------------HKK--------------------- 270
            VI    +  LL+ ++ +                  HK                      
Sbjct: 194 YVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHH 253

Query: 271 ---SIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGAEFDIKKEAAWAISNATS 441
              +I  +  W +S +T    +QIQ VI + I+  LV LL   E  ++  A  A+ N  +
Sbjct: 254 TDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVT 313

Query: 442 G 444
           G
Sbjct: 314 G 314

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>IMA4_HUMAN (O00629) Importin alpha-4 subunit (Karyopherin alpha-4 subunit)|
           (Qip1 protein)
          Length = 521

 Score =  150 bits (378), Expect = 2e-36
 Identities = 80/149 (53%), Positives = 99/149 (66%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           H  D  +L D  WALSYL+D  N++IQ VI+SG+ P LV LL H    V   ALR VGNI
Sbjct: 252 HHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNI 311

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTG D QTQ V++  AL     LL T+ K+ I KEA W +SNITAGN+ Q+QAVI AN++
Sbjct: 312 VTGTDEQTQVVLNCDALSHFPALL-THPKEKINKEAVWFLSNITAGNQQQVQAVIDANLV 370

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
             ++HLL   +F  +KEAAWAISN T  G
Sbjct: 371 PMIIHLLDKGDFGTQKEAAWAISNLTISG 399



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 26/83 (31%), Positives = 46/83 (55%)
 Frame = +1

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           +I +  LP L++ L  +   S++ EA W ++NI +G  +Q QAV+Q+N +   + LL   
Sbjct: 110 LIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSP 169

Query: 391 EFDIKKEAAWAISNATSGGHMIR 459
             ++ ++A WA+ N    G   R
Sbjct: 170 HQNVCEQAVWALGNIIGDGPQCR 192



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 2/133 (1%)
 Frame = +1

Query: 40  ALSYLSDGTNDKIQSVIESGVFPRLVELLLHP-SASVLIPALRTVGNIVTGDDLQTQ*VI 216
           A   LS   N  I  +I+SG+ P LV  L    + S+   A   + NI +G   QTQ V+
Sbjct: 95  ARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVV 154

Query: 217 DNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQ-GAE 393
            + A+P  L LL + H +++ ++A W + NI          VI   ++ PL+  +     
Sbjct: 155 QSNAVPLFLRLLHSPH-QNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIP 213

Query: 394 FDIKKEAAWAISN 432
               +   W + N
Sbjct: 214 ITFLRNVTWVMVN 226



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 42/181 (23%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+++ Q+V++S   P  + LL  P  +V   A+  +GNI+        
Sbjct: 134 EAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRD 193

Query: 208 *VIDNQALPCLLNLLTTN------------------HKK--------------------- 270
            VI    +  LL+ ++ +                  HK                      
Sbjct: 194 YVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHH 253

Query: 271 ---SIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGAEFDIKKEAAWAISNATS 441
              +I  +  W +S +T    +QIQ VI + I+  LV LL   E  ++  A  A+ N  +
Sbjct: 254 TDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVT 313

Query: 442 G 444
           G
Sbjct: 314 G 314

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>IMA3_MOUSE (O35344) Importin alpha-3 subunit (Karyopherin alpha-3 subunit)|
           (Importin alpha Q2)
          Length = 521

 Score =  144 bits (363), Expect = 1e-34
 Identities = 79/146 (54%), Positives = 97/146 (66%)
 Frame = +1

Query: 10  DEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTG 189
           D  +L D  WALSYL+DG N++IQ VI+SGV P LV LL H    V   ALR VGNIVTG
Sbjct: 255 DINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTG 314

Query: 190 DDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPL 369
            D QTQ V++   L    NLL ++ K+ I KEA W +SNITAGN+ Q+QAVI A +I  +
Sbjct: 315 TDEQTQVVLNCDVLSHFPNLL-SHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373

Query: 370 VHLLQGAEFDIKKEAAWAISNATSGG 447
           +H L   +F  +KEAAWAISN T  G
Sbjct: 374 IHQLAKGDFGTQKEAAWAISNLTISG 399



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 35/141 (24%), Positives = 63/141 (44%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+ + Q+V++S   P  + LL  P  +V   A+  +GNI+        
Sbjct: 134 EAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRD 193

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQG 387
            VI    +  LL+ +  +   +  +   W I N+               I+  L  L+  
Sbjct: 194 YVISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYH 253

Query: 388 AEFDIKKEAAWAISNATSGGH 450
            + +I  +  WA+S  T GG+
Sbjct: 254 TDINILVDTVWALSYLTDGGN 274



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 2/133 (1%)
 Frame = +1

Query: 40  ALSYLSDGTNDKIQSVIESGVFPRLVELLLHP-SASVLIPALRTVGNIVTGDDLQTQ*VI 216
           A   LS   N  I  +I+SG+ P LV+ L    + S+   A   + NI +G   QTQ V+
Sbjct: 95  ARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVV 154

Query: 217 DNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQ-GAE 393
            + A+P  L LL + H +++ ++A W + NI          VI   ++ PL+  +     
Sbjct: 155 QSNAVPLFLRLLHSPH-QNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIP 213

Query: 394 FDIKKEAAWAISN 432
               +   W I N
Sbjct: 214 ITFLRNVTWVIVN 226



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 26/83 (31%), Positives = 44/83 (53%)
 Frame = +1

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           +I +  LP L+  L  +   S++ EA W ++NI +G   Q QAV+Q+N +   + LL   
Sbjct: 110 LIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSP 169

Query: 391 EFDIKKEAAWAISNATSGGHMIR 459
             ++ ++A WA+ N    G   R
Sbjct: 170 HQNVCEQAVWALGNIIGDGPQCR 192

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>IMA3_HUMAN (O00505) Importin alpha-3 subunit (Karyopherin alpha-3 subunit)|
           (SRP1-gamma)
          Length = 521

 Score =  144 bits (363), Expect = 1e-34
 Identities = 79/146 (54%), Positives = 97/146 (66%)
 Frame = +1

Query: 10  DEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTG 189
           D  +L D  WALSYL+DG N++IQ VI+SGV P LV LL H    V   ALR VGNIVTG
Sbjct: 255 DINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTG 314

Query: 190 DDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPL 369
            D QTQ V++   L    NLL ++ K+ I KEA W +SNITAGN+ Q+QAVI A +I  +
Sbjct: 315 TDEQTQVVLNCDVLSHFPNLL-SHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373

Query: 370 VHLLQGAEFDIKKEAAWAISNATSGG 447
           +H L   +F  +KEAAWAISN T  G
Sbjct: 374 IHQLAKGDFGTQKEAAWAISNLTISG 399



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 35/141 (24%), Positives = 64/141 (45%)
 Frame = +1

Query: 28  DACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ 207
           +A WAL+ ++ GT+ + Q+V++S   P  + LL  P  +V   A+  +GNI+        
Sbjct: 134 EAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRD 193

Query: 208 *VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQG 387
            VI    +  LL+ ++ +   +  +   W I N+               I+  L  L+  
Sbjct: 194 YVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYH 253

Query: 388 AEFDIKKEAAWAISNATSGGH 450
            + +I  +  WA+S  T GG+
Sbjct: 254 TDINILVDTVWALSYLTDGGN 274



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 2/133 (1%)
 Frame = +1

Query: 40  ALSYLSDGTNDKIQSVIESGVFPRLVELLLHP-SASVLIPALRTVGNIVTGDDLQTQ*VI 216
           A   LS   N  I  +I+SG+ P LV+ L    + S+   A   + NI +G   QTQ V+
Sbjct: 95  ARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVV 154

Query: 217 DNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQ-GAE 393
            + A+P  L LL + H +++ ++A W + NI          VI   ++ PL+  +     
Sbjct: 155 QSNAVPLFLRLLRSPH-QNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIP 213

Query: 394 FDIKKEAAWAISN 432
               +   W I N
Sbjct: 214 ITFLRNVTWVIVN 226



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 26/83 (31%), Positives = 45/83 (54%)
 Frame = +1

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           +I +  LP L+  L  +   S++ EA W ++NI +G   Q QAV+Q+N +   + LL+  
Sbjct: 110 LIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSP 169

Query: 391 EFDIKKEAAWAISNATSGGHMIR 459
             ++ ++A WA+ N    G   R
Sbjct: 170 HQNVCEQAVWALGNIIGDGPQCR 192

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>IMA3_CAEEL (Q19969) Importin alpha-3 subunit (Karyopherin alpha-3 subunit)|
          Length = 514

 Score =  144 bits (362), Expect = 1e-34
 Identities = 78/149 (52%), Positives = 96/149 (64%)
 Frame = +1

Query: 1   HSQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNI 180
           H QD  +L D  WALSYL+DG N+ IQ VIE+ V   LV LL H    V   ALR VGNI
Sbjct: 245 HHQDTNILIDTVWALSYLTDGGNEHIQMVIEAQVVTHLVPLLGHVDVKVQTAALRAVGNI 304

Query: 181 VTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANII 360
           VTG D QTQ V+D+  L  +  LL  ++K+ I KEA W +SNITAGN+ Q+Q V  A I+
Sbjct: 305 VTGTDEQTQLVLDSGVLRFMPGLL-AHYKEKINKEAVWFVSNITAGNQQQVQDVFDAGIM 363

Query: 361 GPLVHLLQGAEFDIKKEAAWAISNATSGG 447
             ++HLL   +F  +KEAAWAISN T  G
Sbjct: 364 PMIIHLLDRGDFPTQKEAAWAISNVTISG 392



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 34/149 (22%), Positives = 66/149 (44%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           S D  +  +A WAL+ ++ GT+++ Q+V+ +G  P  ++LL   + +V   ++  +GNI+
Sbjct: 119 STDPNLQFEAAWALTNIASGTSEQTQAVVNAGAVPLFLQLLSCGNLNVCEQSVWALGNII 178

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIG 363
                     ++   L  LL  +         +   W I N+           +   I+ 
Sbjct: 179 GDGPHFRDYCLELGILQPLLQFINPEIPIGFLRNVTWVIVNLCRCKDPAPSPAVVRTILP 238

Query: 364 PLVHLLQGAEFDIKKEAAWAISNATSGGH 450
            L  L+   + +I  +  WA+S  T GG+
Sbjct: 239 ALSLLIHHQDTNILIDTVWALSYLTDGGN 267



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 38/144 (26%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIV 183
           S   E LT    A   LS   N  I  +I SG+ P LV+ L     ++   A   + NI 
Sbjct: 77  SDPAEQLTAVQQARKMLSTDRNPPIDDLIGSGILPVLVQCLSSTDPNLQFEAAWALTNIA 136

Query: 184 TGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIG 363
           +G   QTQ V++  A+P  L LL+  +  ++ +++ W + NI           ++  I+ 
Sbjct: 137 SGTSEQTQAVVNAGAVPLFLQLLSCGN-LNVCEQSVWALGNIIGDGPHFRDYCLELGILQ 195

Query: 364 PLVHLLQ-GAEFDIKKEAAWAISN 432
           PL+  +         +   W I N
Sbjct: 196 PLLQFINPEIPIGFLRNVTWVIVN 219



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 23/83 (27%), Positives = 44/83 (53%)
 Frame = +1

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           +I +  LP L+  L++    +++ EA W ++NI +G  +Q QAV+ A  +   + LL   
Sbjct: 104 LIGSGILPVLVQCLSSTDP-NLQFEAAWALTNIASGTSEQTQAVVNAGAVPLFLQLLSCG 162

Query: 391 EFDIKKEAAWAISNATSGGHMIR 459
             ++ +++ WA+ N    G   R
Sbjct: 163 NLNVCEQSVWALGNIIGDGPHFR 185



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = +1

Query: 331 IQAVIQANIIGPLVHLLQGAEFDIKKEAAWAISNATSG 444
           I  +I + I+  LV  L   + +++ EAAWA++N  SG
Sbjct: 101 IDDLIGSGILPVLVQCLSSTDPNLQFEAAWALTNIASG 138

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>IMA2_CAEEL (P91276) Importin alpha-2 subunit (Karyopherin alpha-2 subunit)|
          Length = 531

 Score =  130 bits (326), Expect = 2e-30
 Identities = 65/146 (44%), Positives = 96/146 (65%)
 Frame = +1

Query: 10  DEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTG 189
           D +V  DACWA+SYL+DG +++I+   ESGV P +V      + +++ PALRT+GN+ TG
Sbjct: 274 DRQVRQDACWAVSYLTDGPDEQIELARESGVLPHVVAFFKE-AENLVAPALRTLGNVATG 332

Query: 190 DDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPL 369
           +D  TQ VID  +L  +L L+      SI KE CW +SNI AG + QIQAV+ AN++  L
Sbjct: 333 NDSLTQAVIDLGSLDEILPLMEKTRSSSIVKECCWLVSNIIAGTQKQIQAVLDANLLPVL 392

Query: 370 VHLLQGAEFDIKKEAAWAISNATSGG 447
           +++L+  +   + EA+WA+SN   GG
Sbjct: 393 INVLKSGDHKCQFEASWALSNLAQGG 418



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 6/152 (3%)
 Frame = +1

Query: 7   QDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVT 186
           ++E V  +A WAL+ +  G+ ++  + +E+GV   L+ L +H SA +   AL  V NI  
Sbjct: 144 ENERVQYEAAWALTNIVSGSTEQTIAAVEAGVTIPLIHLSVHQSAQISEQALWAVANIAG 203

Query: 187 GDDLQTQ*VIDNQALPCLLNL------LTTNHKKSIKKEACWTISNITAGNRDQIQAVIQ 348
                   VI    +  L++L      L  +H ++I     W  SN+           + 
Sbjct: 204 DSSQLRDYVIKCHGVEALMHLMEKVDQLGDSHVRTI----AWAFSNMCRHKNPHAPLEVL 259

Query: 349 ANIIGPLVHLLQGAEFDIKKEAAWAISNATSG 444
             +   LV L+Q  +  ++++A WA+S  T G
Sbjct: 260 RVLSKGLVKLVQHTDRQVRQDACWAVSYLTDG 291



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 24/83 (28%), Positives = 45/83 (54%)
 Frame = +1

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           VI    L  L+  L+  +++ ++ EA W ++NI +G+ +Q  A ++A +  PL+HL    
Sbjct: 128 VIHCGLLQALVQALSVENER-VQYEAAWALTNIVSGSTEQTIAAVEAGVTIPLIHLSVHQ 186

Query: 391 EFDIKKEAAWAISNATSGGHMIR 459
              I ++A WA++N       +R
Sbjct: 187 SAQISEQALWAVANIAGDSSQLR 209



 Score = 35.4 bits (80), Expect = 0.073
 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
 Frame = +1

Query: 4   SQDEEVLTDACWALSYLSD-GTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTV 171
           S D +   +A WALS L+  GTN ++ +++E  V P L + LL  +  +L   L T+
Sbjct: 398 SGDHKCQFEASWALSNLAQGGTNRQVVAMLEDNVVPALCQALLQTNTDMLNNTLETL 454



 Score = 28.5 bits (62), Expect = 8.9
 Identities = 14/38 (36%), Positives = 20/38 (52%)
 Frame = +1

Query: 331 IQAVIQANIIGPLVHLLQGAEFDIKKEAAWAISNATSG 444
           I  VI   ++  LV  L      ++ EAAWA++N  SG
Sbjct: 125 IDEVIHCGLLQALVQALSVENERVQYEAAWALTNIVSG 162

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>IMA2_ORYSA (Q9FYP9) Importin alpha-2 subunit|
          Length = 528

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 45/149 (30%), Positives = 82/149 (55%), Gaps = 7/149 (4%)
 Frame = +1

Query: 7   QDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLV-ELLLHPSASVLIPALRTVGNIV 183
           +DEE+ T+  W + YLS  ++  I  ++ S V   L+  L    +  +LIP LR +GN++
Sbjct: 275 EDEELATEVAWVVVYLSALSDRGISLIVRSSVPQLLIGRLFSSENLQLLIPVLRGLGNLI 334

Query: 184 TGDDLQTQ*VID------NQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVI 345
             DD     V+       +QAL  L+  L ++++  ++KE+ W +SNI AG+ +  + + 
Sbjct: 335 AADDYMVDSVLTVGHNIIDQALSGLIKCLKSDNRV-LRKESSWALSNIAAGSFEHKKLIF 393

Query: 346 QANIIGPLVHLLQGAEFDIKKEAAWAISN 432
            +     L+ L+   +FDI++EAA+ + N
Sbjct: 394 ASEATPVLIRLVTSMQFDIRREAAYTLGN 422



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
 Frame = +1

Query: 76  IQSVIESGVFPRLVELLLHPSASV-LIPALRTVGNIVTGDDLQTQ*VIDNQALPCLLNLL 252
           + + I++G  P LV+ L   S+   L+ A   + NI  G+  +T+ ++   ALP L+  L
Sbjct: 128 VDTAIKAGAVPLLVQYLSFGSSDEQLLEAAWCLTNIAAGEPEETKSLLP--ALPLLIAHL 185

Query: 253 TTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGAEFDIKKEAAWAISN 432
                  + ++  W I N+     +    ++    + PL  L+  ++    + AAWA+SN
Sbjct: 186 GEKSSTLVAEQCAWAIGNVAGEGAELRSTLLAQGALRPLTRLMFSSKGSTARTAAWAMSN 245

Query: 433 ATSG 444
              G
Sbjct: 246 LIKG 249



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 21/78 (26%), Positives = 40/78 (51%)
 Frame = +1

Query: 226 ALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGAEFDIK 405
           A+P L+  L+         EA W ++NI AG  ++ ++++ A  +  + HL + +   + 
Sbjct: 136 AVPLLVQYLSFGSSDEQLLEAAWCLTNIAAGEPEETKSLLPALPL-LIAHLGEKSSTLVA 194

Query: 406 KEAAWAISNATSGGHMIR 459
           ++ AWAI N    G  +R
Sbjct: 195 EQCAWAIGNVAGEGAELR 212

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>SPAG6_MOUSE (Q9JLI7) Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme|
           central apparatus protein)
          Length = 507

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 36/134 (26%), Positives = 62/134 (46%)
 Frame = +1

Query: 31  ACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ* 210
           A  AL  L++  +D  ++V++  + P+LV  L   +      A   +  +        Q 
Sbjct: 61  AALALGRLANYNDDLAEAVVKGDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA 120

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           ++D  AL  L+  L  +    +K+ A W +  I   N +  QAV+ A  I  LV  +Q  
Sbjct: 121 IVDCGALDTLVICLE-DFDPGVKEAAAWALGYIARHNTELSQAVVDAGAIPLLVLCIQEP 179

Query: 391 EFDIKKEAAWAISN 432
           E  +K+ AA A+S+
Sbjct: 180 EIALKRIAASALSD 193



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 29/144 (20%), Positives = 64/144 (44%), Gaps = 2/144 (1%)
 Frame = +1

Query: 7   QDEEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVT 186
           +DE V  +AC  +  ++  T +  Q ++ +G    +++ +     ++ +P +  +G +  
Sbjct: 263 KDEYVKKNACTLIREIAKHTPELSQLIVNAGGVAAVIDCIGSCKGNIRLPGIMMLGYVAA 322

Query: 187 GDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGP 366
             +     VI ++ +P L   L+   +  IK  A W +  +     +  +AV   N +  
Sbjct: 323 HSENLAMAVIISKGVPQLSICLSEEPEDHIKAAAAWALGQLGRHTPEHARAVAVTNTLPV 382

Query: 367 LVHLLQGAEF--DIKKEAAWAISN 432
           L+ L    E   D++ ++  AI N
Sbjct: 383 LLSLYMSPESSEDLQLKSKKAIKN 406



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 27/125 (21%), Positives = 58/125 (46%)
 Frame = +1

Query: 31  ACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ* 210
           A  ALS +S  + +  Q+V+++G    L +++L+P A +    L  +  I        + 
Sbjct: 187 AASALSDISKHSPELAQTVVDAGAIAHLAQMILNPDAKLKRQVLSALSQIAKHSVDLAEM 246

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           V++ +  P +L  L  +  + +KK AC  I  I     +  Q ++ A  +  ++  +   
Sbjct: 247 VVEAEIFPVVLTCL-KDKDEYVKKNACTLIREIAKHTPELSQLIVNAGGVAAVIDCIGSC 305

Query: 391 EFDIK 405
           + +I+
Sbjct: 306 KGNIR 310

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>SPAG6_HUMAN (O75602) Sperm-associated antigen 6 (PF16 protein homolog) (Sperm|
           flagellar protein) (Repro-SA-1)
          Length = 509

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 35/134 (26%), Positives = 62/134 (46%)
 Frame = +1

Query: 31  ACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ* 210
           A  AL  L++  +D  ++V++  + P+LV  L   +      A   +  +        Q 
Sbjct: 61  AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA 120

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           ++D  AL  L+  L  +    +K+ A W +  I   N +  QAV+ A  +  LV  +Q  
Sbjct: 121 IVDCGALDTLVICLE-DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179

Query: 391 EFDIKKEAAWAISN 432
           E  +K+ AA A+S+
Sbjct: 180 EIALKRIAASALSD 193



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 24/114 (21%), Positives = 52/114 (45%)
 Frame = +1

Query: 31  ACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ* 210
           A  ALS ++  + +  Q+V+++G    L +++L+P A +    L  +  +        + 
Sbjct: 187 AASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEM 246

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLV 372
           V++ +  P +L  L  +  + +KK A   I  I     +  Q V+ A  +  ++
Sbjct: 247 VVEAEIFPVVLTCL-KDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVI 299

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>IMA1_CAEEL (Q22560) Importin alpha-1 subunit (Karyopherin alpha-1 subunit)|
          Length = 524

 Score = 36.2 bits (82), Expect = 0.043
 Identities = 19/94 (20%), Positives = 46/94 (48%)
 Frame = +1

Query: 169 VGNIVTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQ 348
           + +I+      T+ +ID   L  L   +  ++   + +E C+ ISNI       I  +I 
Sbjct: 305 INSIIQATGYFTEEMIDAGLLEVLKGFVNVSY---MSQEVCFIISNICVEGEQTIDKLIS 361

Query: 349 ANIIGPLVHLLQGAEFDIKKEAAWAISNATSGGH 450
           + ++  +  +++ +E+  ++EAA+ I +  +  +
Sbjct: 362 SGVLREVARVMEASEYRSRREAAFVICHCCASAN 395

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>GDS1_BOVIN (Q04173) Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21|
           stimulatory GDP/GTP exchange protein) (SMG GDS protein)
           (Exchange factor smgGDS)
          Length = 558

 Score = 33.5 bits (75), Expect = 0.28
 Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
 Frame = +1

Query: 88  IESGVFPRLVELLLHPSASVLIPALRTVGNI-VTGDDLQTQ*VIDNQALPCLLNLLTTNH 264
           +++G+   LV+LL      VL+   R +GNI      LQ Q +I+   +P L+ LL  + 
Sbjct: 86  VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQ-LINMGVIPTLVKLLGIHC 144

Query: 265 KKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGAEFDIKKEAAWAI 426
           +K+   E C       A      +     NI   LV L +      K+E  + +
Sbjct: 145 QKAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMVFEV 198

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>PUB14_ARATH (Q8VZ40) E3 ubiquitin ligase PUB14 (EC 6.3.2.-) (Prototypical U-box|
           domain protein 14)
          Length = 632

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 33/134 (24%), Positives = 62/134 (46%)
 Frame = +1

Query: 31  ACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGDDLQTQ* 210
           A   L  L+    D    + E+G  P LVELL  P       ++  + N+   +  +   
Sbjct: 365 AAGELRLLAKRNVDNRVCIAEAGAIPLLVELLSSPDPRTQEHSVTALLNLSINEGNKGA- 423

Query: 211 VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLLQGA 390
           ++D  A+  ++ +L  N     ++ A  T+ +++  + +++ A+  A  I  L+ LL+  
Sbjct: 424 IVDAGAITDIVEVL-KNGSMEARENAAATLFSLSVIDENKV-AIGAAGAIQALISLLEEG 481

Query: 391 EFDIKKEAAWAISN 432
               KK+AA AI N
Sbjct: 482 TRRGKKDAATAIFN 495

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>GDS1A_XENLA (O93614) Rap1 GTPase-GDP dissociation stimulator 1-A (RalB-binding|
           protein-A) (Rap1gds1-A protein) (smgGDS-A) (XsmgGDS-A)
          Length = 607

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 9/107 (8%)
 Frame = +1

Query: 88  IESGVFPRLVELLLHPSASVLIPALRTVGNI---------VTGDDLQTQ*VIDNQALPCL 240
           +E+G+ P LV+LL      VL+   R +GNI             +   Q V+D+    C 
Sbjct: 86  VEAGLIPPLVQLLHSKDQEVLLQTGRALGNICYDNHEGRRAVDQEGGAQIVVDHLRSMC- 144

Query: 241 LNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLVHLL 381
              LT    + +    C  + N ++ N      +IQ  +I  LV LL
Sbjct: 145 --TLTDPSSEKLMTVFCGMLMNYSSENDSLQTQLIQMGVIPILVDLL 189

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>PLAK_XENLA (P30998) Junction plakoglobin (Desmoplakin III)|
          Length = 738

 Score = 32.3 bits (72), Expect = 0.62
 Identities = 40/145 (27%), Positives = 70/145 (48%), Gaps = 2/145 (1%)
 Frame = +1

Query: 13  EEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGD 192
           E++L      L  LS   ++K  +++E+G    L + L   S  ++   L T+ N+   D
Sbjct: 321 EKLLWTTSRVLKVLSVCPSNK-PAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNL--SD 377

Query: 193 DLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLV 372
               Q  +DN  L  L+N L+++   ++   A  T+SN+T  N      V Q+N +  L+
Sbjct: 378 VATKQEGLDN-VLKILVNQLSSDDV-NVLTCATGTLSNLTCNNGRNKTLVTQSNGVESLI 435

Query: 373 HLLQGA--EFDIKKEAAWAISNATS 441
           H +  A  + DI + A  A+ + TS
Sbjct: 436 HTILRASDKDDIAEPAVCAMRHLTS 460

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>IMB1_YEAST (Q06142) Importin beta-1 subunit (Karyopherin beta-1 subunit)|
           (Importin 95)
          Length = 861

 Score = 32.0 bits (71), Expect = 0.80
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 6/75 (8%)
 Frame = +1

Query: 157 ALRTVGNIVTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQ 336
           A+   G+I+ G D   +    +QALP +LNL+  +    +K+   W I  I     + I 
Sbjct: 389 AVMAFGSIMDGPDKVQRTYYVHQALPSILNLM-NDQSLQVKETTAWCIGRIADSVAESID 447

Query: 337 ------AVIQANIIG 363
                  V+QA +IG
Sbjct: 448 PQQHLPGVVQACLIG 462

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>SEC6_YEAST (P32844) Exocyst complex component SEC6|
          Length = 805

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 16/60 (26%), Positives = 32/60 (53%)
 Frame = -3

Query: 186 SDDVTHRAQSWNENRSRRVQEKLHKPRKNARFNHRLDLVISSIRQVRESPAGISEHLLVL 7
           SD +T R ++W    S  ++++++       +NH+ D+   SI    E P G+ E+L+ +
Sbjct: 496 SDLLTKRQKNWISKISEEIKKQIN-------YNHKYDIDPESITPEDECPGGLVEYLIAV 548

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>IMB1_SCHPO (O13864) Importin beta-1 subunit (Karyopherin beta-1 subunit)|
           (Importin 95)
          Length = 863

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
 Frame = +1

Query: 157 ALRTVGNIVTGDDLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQ 336
           A+   G+++ G ++     + NQALP L+N++  +    +K    W +  I++   D I 
Sbjct: 386 AVMAFGSVLEGPNVAMLTPLVNQALPVLINMM-VDPVIFVKDTTAWALGQISSFVADAIN 444

Query: 337 AVIQANIIGPLVH-LLQGAEFD--IKKEAAWAISN 432
             I    + P+V  LLQG   +  I     WA  N
Sbjct: 445 PEIH---LSPMVSALLQGLTDNPRIVANCCWAFMN 476

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>PSMR1_HALSA (Q9HNP9) Proteasome-activating nucleotidase 1 (Proteasome|
           regulatory subunit 1)
          Length = 411

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 15/37 (40%), Positives = 21/37 (56%)
 Frame = -3

Query: 240 ETGKRLVINDSLSLQIITSDDVTHRAQSWNENRSRRV 130
           E G R+ INDS S+Q +  D+   RAQ+   + S  V
Sbjct: 113 EVGDRVAINDSFSVQRVLDDETDARAQAMEVDESPSV 149

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>PLAK_HUMAN (P14923) Junction plakoglobin (Desmoplakin-3) (Desmoplakin III)|
          Length = 743

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 2/145 (1%)
 Frame = +1

Query: 13  EEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGD 192
           E++L      L  LS   ++K  +++E+G    L + L   S  ++   L T+ N+    
Sbjct: 323 EKLLWTTSRVLKVLSVCPSNK-PAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNL---S 378

Query: 193 DLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLV 372
           D+ T+       L  L+N L+ +   ++   A  T+SN+T  N      V Q + +  L+
Sbjct: 379 DVATKQEGLESVLKILVNQLSVDDV-NVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI 437

Query: 373 H--LLQGAEFDIKKEAAWAISNATS 441
           H  L  G + DI + A  A+ + TS
Sbjct: 438 HAILRAGDKDDITEPAVCALRHLTS 462

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>PLAK_RAT (Q6P0K8) Junction plakoglobin|
          Length = 745

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 2/145 (1%)
 Frame = +1

Query: 13  EEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGD 192
           E++L      L  LS   ++K  +++E+G    L + L   S  ++   L T+ N+    
Sbjct: 325 EKLLWTTSRVLKVLSVCPSNK-PAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNL---S 380

Query: 193 DLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLV 372
           D+ T+       L  L+N L+ +   ++   A  T+SN+T  N      V Q + +  L+
Sbjct: 381 DVATKQEGLENVLKILVNQLSVDDV-NVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI 439

Query: 373 H--LLQGAEFDIKKEAAWAISNATS 441
           H  L  G + DI + A  A+ + TS
Sbjct: 440 HAILRAGDKDDITEPAVCALRHLTS 464

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>PLAK_PIG (Q8WNW3) Junction plakoglobin|
          Length = 745

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 2/145 (1%)
 Frame = +1

Query: 13  EEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGD 192
           E++L      L  LS   ++K  +++E+G    L + L   S  ++   L T+ N+    
Sbjct: 325 EKLLWTTSRVLKVLSVCPSNK-PAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNL---S 380

Query: 193 DLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLV 372
           D+ T+       L  L+N L+ +   ++   A  T+SN+T  N      V Q + +  L+
Sbjct: 381 DVATKQEGLESVLKILVNQLSVDDV-NVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI 439

Query: 373 H--LLQGAEFDIKKEAAWAISNATS 441
           H  L  G + DI + A  A+ + TS
Sbjct: 440 HAILRAGDKDDITEPAVCALRHLTS 464

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>PLAK_MOUSE (Q02257) Junction plakoglobin (Desmoplakin-3) (Desmoplakin III)|
          Length = 745

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 2/145 (1%)
 Frame = +1

Query: 13  EEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGD 192
           E++L      L  LS   ++K  +++E+G    L + L   S  ++   L T+ N+    
Sbjct: 325 EKLLWTTSRVLKVLSVCPSNK-PAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNL---S 380

Query: 193 DLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLV 372
           D+ T+       L  L+N L+ +   ++   A  T+SN+T  N      V Q + +  L+
Sbjct: 381 DVATKQEGLESVLKILVNQLSVDDV-NVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI 439

Query: 373 H--LLQGAEFDIKKEAAWAISNATS 441
           H  L  G + DI + A  A+ + TS
Sbjct: 440 HAILRAGDKDDITEPAVCALRHLTS 464

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>PLAK_BOVIN (Q8SPJ1) Junction plakoglobin (Desmoplakin III)|
          Length = 745

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 2/145 (1%)
 Frame = +1

Query: 13  EEVLTDACWALSYLSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIPALRTVGNIVTGD 192
           E++L      L  LS   ++K  +++E+G    L + L   S  ++   L T+ N+    
Sbjct: 325 EKLLWTTSRVLKVLSVCPSNK-PAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNL---S 380

Query: 193 DLQTQ*VIDNQALPCLLNLLTTNHKKSIKKEACWTISNITAGNRDQIQAVIQANIIGPLV 372
           D+ T+       L  L+N L+ +   ++   A  T+SN+T  N      V Q + +  L+
Sbjct: 381 DVATKQEGLESVLKILVNQLSVDDV-NVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI 439

Query: 373 H--LLQGAEFDIKKEAAWAISNATS 441
           H  L  G + DI + A  A+ + TS
Sbjct: 440 HAILRAGDKDDITEPAVCALRHLTS 464

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>YL112_MIMIV (Q5UPI6) Putative ankyrin repeat protein L112|
          Length = 457

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 13/29 (44%), Positives = 18/29 (62%)
 Frame = +1

Query: 367 LVHLLQGAEFDIKKEAAWAISNATSGGHM 453
           +V  L G   D +KE  WAI++A  GGH+
Sbjct: 236 VVEYLIGLGVDPRKEKCWAITSACQGGHL 264

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>DHE2_NEUCR (P00365) NAD-specific glutamate dehydrogenase (EC 1.4.1.2) (NAD-GDH)|
          Length = 1050

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
 Frame = -3

Query: 252  QEVQETG-KRLVINDSLSLQIITSDDVTHRAQSWNENRSRR 133
            +E ++TG  R V++D LSL I + D+   R++ W+  + RR
Sbjct: 942  REHEQTGLPRSVLSDKLSLAITSLDEDLQRSELWDNEKIRR 982

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>TAGH_LACLA (Q9CH26) Teichoic acids export ATP-binding protein tagH (EC|
           3.6.3.40)
          Length = 466

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 13/30 (43%), Positives = 21/30 (70%)
 Frame = -3

Query: 159 SWNENRSRRVQEKLHKPRKNARFNHRLDLV 70
           S N ++SRRVQ ++ +  KN + NH+L L+
Sbjct: 280 SQNPSKSRRVQREVTEELKNKKDNHKLSLM 309

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>AEP3_KLULA (Q6CIF3) ATPase expression protein 3|
          Length = 593

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 3/51 (5%)
 Frame = +1

Query: 13  EEVLTDACWALSYLSDGTNDKIQ---SVIESGVFPRLVELLLHPSASVLIP 156
           EEVL+D      Y+   T+ K     S ++ G+ P+L++ LLHPS   + P
Sbjct: 159 EEVLSDIQEFEDYIGLLTHTKFHHKGSSLQDGIIPKLLKNLLHPSNLRIAP 209

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>GCN2_YEAST (P15442) Serine/threonine-protein kinase GCN2 (EC 2.7.11.1)|
          Length = 1590

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 19/47 (40%), Positives = 25/47 (53%)
 Frame = -3

Query: 279  LDAFLVIGSQEVQETGKRLVINDSLSLQIITSDDVTHRAQSWNENRS 139
            LD FL +  QE   TG + +INDSL+L      D     + W+EN S
Sbjct: 1412 LDEFLTLYQQE---TGNKSLINDSLTL-----GDKADEFKRWDENSS 1450

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>NANA_STAAW (Q8NYC7) N-acetylneuraminate lyase (EC 4.1.3.3) (N-acetylneuraminic|
           acid aldolase) (N-acetylneuraminate pyruvate-lyase)
           (Sialic acid lyase) (Sialate lyase) (Sialic acid
           aldolase)
          Length = 293

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = +1

Query: 52  LSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIP 156
           L   +ND I++V+  G++P L E+L H      +P
Sbjct: 235 LQHDSNDIIETVLSMGIYPTLKEILRHRGIDAGLP 269

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>NANA_STAAS (Q6GCF6) N-acetylneuraminate lyase (EC 4.1.3.3) (N-acetylneuraminic|
           acid aldolase) (N-acetylneuraminate pyruvate-lyase)
           (Sialic acid lyase) (Sialate lyase) (Sialic acid
           aldolase)
          Length = 293

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = +1

Query: 52  LSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIP 156
           L   +ND I++V+  G++P L E+L H      +P
Sbjct: 235 LQHDSNDIIETVLSMGIYPTLKEILRHRGIDAGLP 269

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>NANA_STAAR (Q6GK01) N-acetylneuraminate lyase (EC 4.1.3.3) (N-acetylneuraminic|
           acid aldolase) (N-acetylneuraminate pyruvate-lyase)
           (Sialic acid lyase) (Sialate lyase) (Sialic acid
           aldolase)
          Length = 293

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = +1

Query: 52  LSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIP 156
           L   +ND I++V+  G++P L E+L H      +P
Sbjct: 235 LQHDSNDIIETVLSMGIYPTLKEILRHRGIDAGLP 269

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>NANA_STAAN (P99123) N-acetylneuraminate lyase (EC 4.1.3.3) (N-acetylneuraminic|
           acid aldolase) (N-acetylneuraminate pyruvate-lyase)
           (Sialic acid lyase) (Sialate lyase) (Sialic acid
           aldolase)
          Length = 293

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = +1

Query: 52  LSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIP 156
           L   +ND I++V+  G++P L E+L H      +P
Sbjct: 235 LQHDSNDIIETVLSMGIYPTLKEILRHRDIDAGLP 269

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>NANA_STAAM (P63949) N-acetylneuraminate lyase (EC 4.1.3.3) (N-acetylneuraminic|
           acid aldolase) (N-acetylneuraminate pyruvate-lyase)
           (Sialic acid lyase) (Sialate lyase) (Sialic acid
           aldolase)
          Length = 293

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = +1

Query: 52  LSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIP 156
           L   +ND I++V+  G++P L E+L H      +P
Sbjct: 235 LQHDSNDIIETVLSMGIYPTLKEILRHRDIDAGLP 269

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>NANA_STAAC (Q5HJ53) N-acetylneuraminate lyase (EC 4.1.3.3) (N-acetylneuraminic|
           acid aldolase) (N-acetylneuraminate pyruvate-lyase)
           (Sialic acid lyase) (Sialate lyase) (Sialic acid
           aldolase)
          Length = 293

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = +1

Query: 52  LSDGTNDKIQSVIESGVFPRLVELLLHPSASVLIP 156
           L   +ND I++V+  G++P L E+L H      +P
Sbjct: 235 LQHDSNDIIETVLSMGIYPTLKEILRHRGIDAGLP 269

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>DEGP7_ARATH (Q8RY22) Protease Do-like 7 (EC 3.4.21.-)|
          Length = 1097

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 12/40 (30%), Positives = 24/40 (60%)
 Frame = -1

Query: 167 VRRAGMRTEAEGCKRSSTSRGKTPDSITDWILSLVPSDRY 48
           +RR G+R+E E   R ++  G+T   + D ++   P+D++
Sbjct: 279 IRRLGLRSETEQVVRHASPTGETGMLVVDSVVPSGPADKH 318

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>SPA3N_MOUSE (Q91WP6) Serine protease inhibitor A3N precursor (Serpin A3N)|
          Length = 418

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 25/107 (23%), Positives = 51/107 (47%), Gaps = 5/107 (4%)
 Frame = -3

Query: 330 LVPVTSCDV*DSPACFFLDAFLVIGSQEVQETGKR---LVINDSLSLQIITSDDVTHRAQ 160
           +VP+ S +   +P  +F D  L     E++ TG      ++ D   +Q + +       +
Sbjct: 238 IVPMMSMEDLTTP--YFRDEELSCTVVELKYTGNASALFILPDQGRMQQVEASLQPETLR 295

Query: 159 SWNENRSRRVQEKLHKPRKNARFNHRLDLVIS--SIRQVRESPAGIS 25
            W  +   R+ ++LH P+ +   ++ L+ V+S   IR+V  + A +S
Sbjct: 296 KWKNSLKPRMIDELHLPKFSISTDYSLEDVLSKLGIREVFSTQADLS 342

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>VE2_HPV14 (P36783) Regulatory protein E2|
          Length = 483

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 14/38 (36%), Positives = 22/38 (57%)
 Frame = -1

Query: 143 EAEGCKRSSTSRGKTPDSITDWILSLVPSDRYERAQQA 30
           E+ G +  S +  KTP + TD    L P+D  +++QQA
Sbjct: 205 ESPGGQADSNTSSKTPTTATDSTSRLSPADSRKQSQQA 242


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,527,730
Number of Sequences: 219361
Number of extensions: 1307787
Number of successful extensions: 4127
Number of sequences better than 10.0: 55
Number of HSP's better than 10.0 without gapping: 3761
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3976
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3014947676
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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full-length cDNA and EST

Clone Information

BLAST Search Result