>PLC_LISMO (P34024) 1-phosphatidylinositol phosphodiesterase precursor (EC|
           4.6.1.13) (Phosphatidylinositol diacylglycerol-lyase)
           (Phosphatidylinositol-specific phospholipase C) (PI-PLC)
          Length = 317

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 27/90 (30%), Positives = 54/90 (60%), Gaps = 1/90 (1%)
 Frame = +3

Query: 162 KTWMAELGPERLRVHQVVWPGTHNSATAEIGVPF-VTRPFAQCQSLSVYDQLATGCRLLD 338
           K WM+ L P+   +  +  PGTH++ +    + + +T+P AQ Q++S+Y QL  G R +D
Sbjct: 46  KQWMSAL-PDTTNLAALSIPGTHDTMSYNGDITWTLTKPLAQTQTMSLYQQLEAGIRYID 104

Query: 339 VRVQKDRRVCHGPLVASYTVDVVIDDVRRF 428
           +R + +  + HGP+  + ++  V++ + +F
Sbjct: 105 IRAKDNLNIYHGPIFLNASLSGVLETITQF 134

>PLC_BACTU (P08954) 1-phosphatidylinositol phosphodiesterase precursor (EC|
           4.6.1.13) (Phosphatidylinositol diacylglycerol-lyase)
           (Phosphatidylinositol-specific phospholipase C) (PI-PLC)
          Length = 329

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
 Frame = +3

Query: 168 WMAELGPERLRVHQVVWPGTHNSATAEIGVPFVTRPFAQCQSLSVYDQLATGCRLLDV-- 341
           WM  + P+ + + ++  PGTH+S T ++  P + + +   Q      Q+  G R+ D+  
Sbjct: 44  WMQPI-PDNIPLARISIPGTHDSGTFKLQNP-IKQVWGMTQEYDFRYQMDHGARIFDIRG 101

Query: 342 RVQKDRRVC--HGPLVASYTVDVVIDDVRRF 428
           R+  D  +   HGPL    T+   I++ ++F
Sbjct: 102 RLTDDNTIVLHHGPLYLYVTLHEFINEAKQF 132

>PLC_BACCE (P14262) 1-phosphatidylinositol phosphodiesterase precursor (EC|
           4.6.1.13) (Phosphatidylinositol diacylglycerol-lyase)
           (Phosphatidylinositol-specific phospholipase C) (PI-PLC)
          Length = 329

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
 Frame = +3

Query: 168 WMAELGPERLRVHQVVWPGTHNSATAEIGVPFVTRPFAQCQSLSVYDQLATGCRLLDV-- 341
           WM  + P+ + + ++  PGTH+S T ++  P + + +   Q      Q+  G R+ D+  
Sbjct: 44  WMQPI-PDSIPLARISIPGTHDSGTFKLQNP-IKQVWGMTQEYDFRYQMDHGARIFDIRG 101

Query: 342 RVQKDRRVC--HGPLVASYTVDVVIDDVRRF 428
           R+  D  +   HGPL    T+   I++ ++F
Sbjct: 102 RLTDDNTIVLHHGPLYLYVTLHEFINEAKQF 132

>GA2L2_HUMAN (Q8NHY3) GAS2-like protein 2 (Growth arrest-specific 2-like 2)|
           (GAS2-related protein on chromosome 17) (GAR17 protein)
          Length = 880

 Score = 34.3 bits (77), Expect = 0.16
 Identities = 15/35 (42%), Positives = 23/35 (65%)
 Frame = -2

Query: 202 TRSRSGPSSAIHVLRSAGRWPDPGKSWPEADRRLA 98
           TRS   P S +++ R AG+WP+PG  + +A + LA
Sbjct: 625 TRSGVIPRSGVYIPRLAGQWPEPGGPYDKAIQELA 659

>GA2L2_MOUSE (Q5SSG4) GAS2-like protein 2 (Growth arrest-specific 2-like 2)|
          Length = 860

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = -2

Query: 202 TRSRSGPSSAIHVLRSAGRWPDPGKSWPEADRRL 101
           TRS++ P S ++V    GRWP+PG  + +  R L
Sbjct: 610 TRSQAIPRSGVYVPSLGGRWPEPGGPYDKVIREL 643

>MUTS_THET8 (Q56239) DNA mismatch repair protein mutS|
          Length = 818

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
 Frame = -1

Query: 290 LALREGAGDE-GHADLGRGGVVGARPHHLVHPQPL--RPELRHPRLAVRRPVAGP---WE 129
           LALR   G    +A   +GG +  RP  L  P      PE     L V  P+ G    + 
Sbjct: 222 LALRRAQGALLAYARATQGGALSVRPFRLYDPGAFVRLPEASLKALEVFEPLRGQDTLFG 281

Query: 128 VLARGRQAPGQRLLLA 81
           VL   R APG+RLL A
Sbjct: 282 VLDETRTAPGRRLLQA 297

>MUTS_THET2 (P61671) DNA mismatch repair protein mutS|
          Length = 811

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
 Frame = -1

Query: 290 LALREGAGDE-GHADLGRGGVVGARPHHLVHPQPL--RPELRHPRLAVRRPVAGP---WE 129
           LALR   G    +A   +GG +  RP  L  P      PE     L V  P+ G    + 
Sbjct: 215 LALRRAQGALLAYARATQGGALSVRPFRLYDPGAFVRLPEASLKALEVFEPLRGQDTLFG 274

Query: 128 VLARGRQAPGQRLLLA 81
           VL   R APG+RLL A
Sbjct: 275 VLDETRTAPGRRLLQA 290

>PURL_THEMA (Q9X0X3) Phosphoribosylformylglycinamidine synthase II (EC 6.3.5.3)|
           (FGAM synthase II)
          Length = 603

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 19/47 (40%), Positives = 24/47 (51%)
 Frame = -1

Query: 263 EGHADLGRGGVVGARPHHLVHPQPLRPELRHPRLAVRRPVAGPWEVL 123
           EG  DLG GGV+ A    LV    L   +   R+ +R P   PWE+L
Sbjct: 232 EGAQDLGAGGVLSA-TSELVAKGNLGAIVHLDRVPLREPDMEPWEIL 277

>WNK4_HUMAN (Q96J92) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein|
            kinase with no lysine 4) (Protein kinase,
            lysine-deficient 4)
          Length = 1243

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 16/42 (38%), Positives = 21/42 (50%)
 Frame = -1

Query: 314  ELVVDGERLALREGAGDEGHADLGRGGVVGARPHHLVHPQPL 189
            E + + +R A   GAG E   D G+   VG  P  L HP P+
Sbjct: 1068 EALAESDRAAEGLGAGVEEEGDDGKEPQVGGSPQPLSHPSPV 1109

>XKR5_MOUSE (Q5GH66) XK-related protein 5|
          Length = 676

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 27/112 (24%), Positives = 49/112 (43%)
 Frame = +3

Query: 3   ELARADRMAAIGAFFSGQVNRVKEVASQQQALARRLSASGQDFPGSGHRPADRKTWMAEL 182
           E+   ++ +   +FFS     + ++A +  +++R  +A G D PG    P    +   +L
Sbjct: 386 EVGLGEQRSGESSFFSHHHWLLLKLALKTGSVSRINAALGGDSPGCSCPPLLGSSQHCDL 445

Query: 183 GPERLRVHQVVWPGTHNSATAEIGVPFVTRPFAQCQSLSVYDQLATGCRLLD 338
             + L  HQ +     +  T E G  +V  P A+ +SL     L+    L D
Sbjct: 446 QRKPLFSHQDLPSSPCDPLTLEKGSEYVGAPKAEMESLETSSYLSFASELED 497

>VNUA_PRVKA (P33485) Probable nuclear antigen|
          Length = 1733

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 34/98 (34%), Positives = 39/98 (39%), Gaps = 10/98 (10%)
 Frame = -1

Query: 275  GAGDEGHADLGRGGVVGARPHHLVHPQPLRPELRHPRLAVRRPVAGPWEVLAR-----GR 111
            G G+EG   +G GG+ GA P H V  Q             RR  AG      R     GR
Sbjct: 1049 GRGEEGRG-VGPGGLAGAGPVHAVAHQ-------------RRHGAGDEGDRVRGLPPLGR 1094

Query: 110  QAPGQRLL----LARHFLDAVDLPREEGAYG-GHPVRA 12
              PG R+       RH L+A       GA G G P RA
Sbjct: 1095 AGPGDRVAEREQRGRHLLEAGGPEGGRGAGGRGQPERA 1132

>MUTS_THECA (Q9ZIX6) DNA mismatch repair protein mutS|
          Length = 817

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 5/64 (7%)
 Frame = -1

Query: 257 HADLGRGGVVGARPHHLVHPQPL--RPELRHPRLAVRRPVAGP---WEVLARGRQAPGQR 93
           +A   +GG +  RP  L  P  +   PE     L V  P+ G    + VL   R APG+R
Sbjct: 232 YARATQGGALSVRPFRLYDPGAIVRLPEASLKALEVFEPLRGQDTLFGVLDETRTAPGRR 291

Query: 92  LLLA 81
           LL A
Sbjct: 292 LLQA 295

>END4_BACHK (Q6HDN3) Probable endonuclease 4 (EC 3.1.21.2) (Endonuclease IV)|
           (Endodeoxyribonuclease IV)
          Length = 298

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 15/46 (32%), Positives = 22/46 (47%)
 Frame = -1

Query: 275 GAGDEGHADLGRGGVVGARPHHLVHPQPLRPELRHPRLAVRRPVAG 138
           GAG + H ++G G +     HH+VH     P+L H    +  P  G
Sbjct: 224 GAGKDRHENIGFGHIGYKALHHIVH----HPQLTHVPKILETPYVG 265

>END4_BACCZ (Q634Q3) Probable endonuclease 4 (EC 3.1.21.2) (Endonuclease IV)|
           (Endodeoxyribonuclease IV)
          Length = 298

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 15/46 (32%), Positives = 22/46 (47%)
 Frame = -1

Query: 275 GAGDEGHADLGRGGVVGARPHHLVHPQPLRPELRHPRLAVRRPVAG 138
           GAG + H ++G G +     HH+VH     P+L H    +  P  G
Sbjct: 224 GAGKDRHENIGFGHIGYKALHHIVH----HPQLTHVPKILETPYVG 265

>END4_BACCR (Q818H3) Probable endonuclease 4 (EC 3.1.21.2) (Endonuclease IV)|
           (Endodeoxyribonuclease IV)
          Length = 298

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 15/46 (32%), Positives = 22/46 (47%)
 Frame = -1

Query: 275 GAGDEGHADLGRGGVVGARPHHLVHPQPLRPELRHPRLAVRRPVAG 138
           GAG + H ++G G +     HH+VH     P+L H    +  P  G
Sbjct: 224 GAGKDRHENIGFGHIGYKALHHIVH----HPQLMHVPKILETPYVG 265

>END4_BACAN (Q81LV1) Probable endonuclease 4 (EC 3.1.21.2) (Endonuclease IV)|
           (Endodeoxyribonuclease IV)
          Length = 298

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 15/46 (32%), Positives = 22/46 (47%)
 Frame = -1

Query: 275 GAGDEGHADLGRGGVVGARPHHLVHPQPLRPELRHPRLAVRRPVAG 138
           GAG + H ++G G +     HH+VH     P+L H    +  P  G
Sbjct: 224 GAGKDRHENIGFGHIGYKALHHIVH----HPQLTHVPKILETPYVG 265

>MTMR1_MOUSE (Q9Z2C4) Myotubularin-related protein 1 (EC 3.1.3.-)|
          Length = 669

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 13/28 (46%), Positives = 16/28 (57%)
 Frame = -1

Query: 314 ELVVDGERLALREGAGDEGHADLGRGGV 231
           E +  G R ALR G GD+ HAD  R  +
Sbjct: 477 EWISFGHRFALRVGHGDDNHADADRSPI 504

>ATX7_MOUSE (Q8R4I1) Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog)|
          Length = 867

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
 Frame = -1

Query: 284 LREGAGDE--GHADLGRGGVVGARPHHLVHPQPLRPELRHPRLAVRRPVA 141
           + E A D+  G      GG   AR      PQPL+P+ +HP L  RRP A
Sbjct: 1   MSERAADDVRGEPRRAAGGAAAARQQQQ-QPQPLQPQRQHPPL--RRPRA 47

>CO2_PANTR (Q8SQ74) Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase)|
           [Contains: Complement C2b fragment; Complement C2a
           fragment]
          Length = 752

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
 Frame = -2

Query: 229 WVPGHT-TWCTRSRSGPSSAIHVLRSAGRWPDPGKSWPEADRRLASACC 86
           W PG   T+       PS A  + +S+G+W  PG     A R L+ A C
Sbjct: 41  WAPGSLLTYSCPQGLYPSPASRLCKSSGQWQTPG-----ATRSLSKAVC 84

>CO2_HUMAN (P06681) Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase)|
           [Contains: Complement C2b fragment; Complement C2a
           fragment]
          Length = 752

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
 Frame = -2

Query: 229 WVPGHT-TWCTRSRSGPSSAIHVLRSAGRWPDPGKSWPEADRRLASACC 86
           W PG   T+       PS A  + +S+G+W  PG     A R L+ A C
Sbjct: 41  WAPGSLLTYSCPQGLYPSPASRLCKSSGQWQTPG-----ATRSLSKAVC 84

>CO2_GORGO (Q863A0) Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase)|
           [Contains: Complement C2b fragment; Complement C2a
           fragment]
          Length = 752

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
 Frame = -2

Query: 229 WVPGHT-TWCTRSRSGPSSAIHVLRSAGRWPDPGKSWPEADRRLASACC 86
           W PG   T+       PS A  + +S+G+W  PG     A R L+ A C
Sbjct: 41  WAPGSLLTYSCPQGLYPSPASRLCKSSGQWQTPG-----ATRSLSKAVC 84

>DAPB_BRAJA (Q89WK2) Dihydrodipicolinate reductase (EC 1.3.1.26) (DHPR)|
          Length = 271

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 27/85 (31%), Positives = 36/85 (42%)
 Frame = -1

Query: 317 GELVVDGERLALREGAGDEGHADLGRGGVVGARPHHLVHPQPLRPELRHPRLAVRRPVAG 138
           G  ++ G+  A   G   + HAD GR G+ GAR    +    LR        +V     G
Sbjct: 167 GTALMLGQAAAAGRGISLDEHADRGRDGITGARKPGNIGFASLRGGTAAGDHSV--SFLG 224

Query: 137 PWEVLARGRQAPGQRLLLARHFLDA 63
           P+E L    QA   R+L A   L A
Sbjct: 225 PFERLTLSHQAE-DRMLFAHGALKA 248


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,475,136
Number of Sequences: 219361
Number of extensions: 956438
Number of successful extensions: 3636
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 3522
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3635
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3014947676
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)