ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baak0b05 |
|---|---|
| Clone Library Name | barley_pub |
>KSG9_ARATH (Q39012) Shaggy-related protein kinase iota (EC 2.7.11.1)| (ASK-iota) Length = 407 Score = 265 bits (677), Expect = 4e-71 Identities = 124/137 (90%), Positives = 134/137 (97%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GGKNGEPK+TISYMAERVVGTGSFGIVFQAKCLETGE+VAIKKVLQDRRYKNRELQLMR Sbjct: 58 GGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNRELQLMRP 117 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 MDHPNV+SLKHCFFSTTSRDELFLNLVMEYVPETLYRVL+HY+++NQRMP+ YVKLY YQ Sbjct: 118 MDHPNVISLKHCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQ 177 Query: 362 LFRGLAYVHTVPGVCHR 412 +FRGLAY+HTVPGVCHR Sbjct: 178 IFRGLAYIHTVPGVCHR 194
>KSG7_ARATH (Q39011) Shaggy-related protein kinase eta (EC 2.7.11.1) (ASK-eta)| (BRASSINOSTEROID-INSENSITIVE 2) (ULTRACURVATA1) Length = 380 Score = 265 bits (676), Expect = 5e-71 Identities = 126/137 (91%), Positives = 133/137 (97%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GGKNGEPK+TISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMR Sbjct: 28 GGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRV 87 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 MDHPNVV LKHCFFSTTS+DELFLNLVMEYVPE+LYRVLKHYS+ANQRMPL+YVKLYMYQ Sbjct: 88 MDHPNVVCLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQ 147 Query: 362 LFRGLAYVHTVPGVCHR 412 +FRGLAY+H V GVCHR Sbjct: 148 IFRGLAYIHNVAGVCHR 164
>KSG6_ARATH (Q39010) Shaggy-related protein kinase dzeta (EC 2.7.11.1)| (ASK-dzeta) Length = 412 Score = 263 bits (673), Expect = 1e-70 Identities = 124/137 (90%), Positives = 133/137 (97%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GGKNGEPK+TISYMAERVVGTGSFGIVFQAKCLETGE+VAIKKVLQDRRYKNRELQLMR Sbjct: 60 GGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNRELQLMRL 119 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 MDHPNVVSLKHCFFSTT+RDELFLNLVMEYVPETLYRVLKHY+++NQRMP+ YVKLY YQ Sbjct: 120 MDHPNVVSLKHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQ 179 Query: 362 LFRGLAYVHTVPGVCHR 412 +FRGLAY+HT PGVCHR Sbjct: 180 IFRGLAYIHTAPGVCHR 196
>KSG5_ARATH (Q8VZD5) Shaggy-related protein kinase epsilon (EC 2.7.11.1)| (ASK-epsilon) Length = 410 Score = 240 bits (613), Expect = 1e-63 Identities = 113/137 (82%), Positives = 125/137 (91%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GGKNG+PK+TISYMAER+VG GSFGIVFQAKCLETGETVAIKKVLQD+RYKNRELQ MR Sbjct: 62 GGKNGQPKQTISYMAERIVGQGSFGIVFQAKCLETGETVAIKKVLQDKRYKNRELQTMRL 121 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 +DHPNVVSLKHCFFSTT +DEL+LNLV+EYVPET+YRV KHYS ANQRMP+IYVKLY YQ Sbjct: 122 LDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQ 181 Query: 362 LFRGLAYVHTVPGVCHR 412 + R LAY+H GVCHR Sbjct: 182 ICRALAYIHGGVGVCHR 198
>KSG1_ARATH (P43288) Shaggy-related protein kinase alpha (EC 2.7.11.1)| (ASK-alpha) Length = 405 Score = 240 bits (612), Expect = 1e-63 Identities = 111/137 (81%), Positives = 126/137 (91%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GG+NG+PK+TISYMAERVVG GSFG+VFQAKCLETGETVAIKKVLQDRRYKNRELQ MR Sbjct: 57 GGRNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNRELQTMRL 116 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 +DHPNVVSLKHCFFSTT +DEL+LNLV+EYVPET++RV+KHY+ NQRMPLIYVKLY YQ Sbjct: 117 LDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQ 176 Query: 362 LFRGLAYVHTVPGVCHR 412 +FR L+Y+H GVCHR Sbjct: 177 IFRALSYIHRCIGVCHR 193
>KSG3_ARATH (P43289) Shaggy-related protein kinase gamma (EC 2.7.11.1)| (ASK-gamma) Length = 409 Score = 239 bits (611), Expect = 2e-63 Identities = 110/137 (80%), Positives = 126/137 (91%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GG+NG+PK+TISYMAERVVG GSFG+VFQAKCLETGETVAIKKVLQDRRYKNRELQ MR Sbjct: 61 GGRNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNRELQTMRL 120 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 +DHPNVVSLKHCFFSTT +DEL+LNLV+EYVPET++RV+KHY+ NQRMPL+YVKLY YQ Sbjct: 121 LDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQ 180 Query: 362 LFRGLAYVHTVPGVCHR 412 +FR L+Y+H GVCHR Sbjct: 181 IFRSLSYIHRCIGVCHR 197
>MSK1_MEDSA (P51137) Glycogen synthase kinase-3 homolog MsK-1 (EC 2.7.11.1)| Length = 411 Score = 239 bits (610), Expect = 2e-63 Identities = 110/137 (80%), Positives = 126/137 (91%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GG+NG+PK+TISYMAERVVG GSFG+VFQAKCLETGETVAIKKVLQD+RYKNRELQ MR Sbjct: 63 GGRNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDKRYKNRELQTMRL 122 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 +DHPNVVSLKHCFFSTT +DEL+LNLV+EYVPET++RV+KHYS NQRMP+IYVKLY YQ Sbjct: 123 LDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYSKLNQRMPMIYVKLYTYQ 182 Query: 362 LFRGLAYVHTVPGVCHR 412 +FR L+Y+H GVCHR Sbjct: 183 IFRALSYIHRCIGVCHR 199
>MSK3_MEDSA (P51139) Glycogen synthase kinase-3 homolog MsK-3 (EC 2.7.11.1)| Length = 411 Score = 234 bits (598), Expect = 5e-62 Identities = 109/137 (79%), Positives = 124/137 (90%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GGKNG+PK+TISYMAERVVG GSFG+VFQAKCLETGETVAIKKVLQD+RYKNRELQ MR Sbjct: 62 GGKNGQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDKRYKNRELQTMRL 121 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 +DHPNVVSLKHCFFSTT +DEL+LNLV+EYVPET+ RV++HY+ NQRMP+IYVKLY YQ Sbjct: 122 LDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVSRVIRHYNKMNQRMPMIYVKLYSYQ 181 Query: 362 LFRGLAYVHTVPGVCHR 412 + R LAY+H GVCHR Sbjct: 182 ICRALAYIHNSIGVCHR 198
>MSK2_MEDSA (P51138) Glycogen synthase kinase-3 homolog MsK-2 (EC 2.7.11.1)| Length = 411 Score = 231 bits (589), Expect = 6e-61 Identities = 107/137 (78%), Positives = 123/137 (89%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GGKNG+PK+TISYMAER VG GSFG+VFQAKCLETGETVAIKKVLQD+RYKNRELQ MR Sbjct: 62 GGKNGQPKQTISYMAERAVGQGSFGVVFQAKCLETGETVAIKKVLQDKRYKNRELQTMRL 121 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 +DHPNVV+LKHCFFSTT +DEL+LNLV+E+VPET++RV++HYS NQRMPLIYVKLY YQ Sbjct: 122 LDHPNVVTLKHCFFSTTEKDELYLNLVLEFVPETVHRVIRHYSKMNQRMPLIYVKLYSYQ 181 Query: 362 LFRGLAYVHTVPGVCHR 412 + R LAY+H GV HR Sbjct: 182 ICRSLAYIHNCVGVSHR 198
>MSK1_TOBAC (Q40518) Shaggy-related protein kinase NtK-1 (EC 2.7.11.1)| Length = 409 Score = 231 bits (588), Expect = 8e-61 Identities = 105/137 (76%), Positives = 124/137 (90%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GG++G+PK+TISYMAER+VG GSFG+VFQAKCLETGETVAIKKVLQD+RYKNRELQ MR Sbjct: 61 GGRHGQPKQTISYMAERIVGQGSFGVVFQAKCLETGETVAIKKVLQDKRYKNRELQTMRL 120 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 +DHPNVV LKHCFFSTT +DE++LNLV+EYVPET++RV+KHY+ NQRMPLI VKLY YQ Sbjct: 121 LDHPNVVCLKHCFFSTTEKDEVYLNLVLEYVPETVHRVIKHYNKLNQRMPLILVKLYTYQ 180 Query: 362 LFRGLAYVHTVPGVCHR 412 +FR L+Y+H GVCHR Sbjct: 181 IFRALSYIHHTIGVCHR 197
>KSG8_ARATH (Q96287) Shaggy-related protein kinase theta (EC 2.7.11.1)| (ASK-theta) Length = 472 Score = 219 bits (559), Expect = 2e-57 Identities = 101/137 (73%), Positives = 120/137 (87%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GG++G+PK+TISYMA+RVVGTGSFG+VFQAKCLETGE VAIKKVLQD+RYKNRELQ+MR Sbjct: 126 GGRDGKPKQTISYMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYKNRELQIMRL 185 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 DHPNVV L+H FFSTT +DEL+LNLV+EYVPET+YR KHY+ NQ MP+I+V+LY YQ Sbjct: 186 QDHPNVVRLRHSFFSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQHMPIIFVQLYTYQ 245 Query: 362 LFRGLAYVHTVPGVCHR 412 + R L Y+H V GVCHR Sbjct: 246 ICRALNYLHRVVGVCHR 262
>KSGT_BRANA (O04160) Shaggy-related protein kinase theta (EC 2.7.11.1)| (ASK-theta) Length = 468 Score = 219 bits (557), Expect = 3e-57 Identities = 101/137 (73%), Positives = 120/137 (87%) Frame = +2 Query: 2 GGKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRS 181 GG++G+PK+TISYMA+RVVGTGSFG+VFQAKCLETGE VAIKKVLQD+RYKNRELQ+MR Sbjct: 122 GGRDGKPKQTISYMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYKNRELQIMRL 181 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 DHPNVV L+H FFSTT +DEL+LNLV+E+VPET+YR LKHY+ NQ MP+I V+LY YQ Sbjct: 182 QDHPNVVRLRHSFFSTTDKDELYLNLVLEFVPETVYRALKHYTKMNQHMPIILVQLYTYQ 241 Query: 362 LFRGLAYVHTVPGVCHR 412 + R L Y+H V GVCHR Sbjct: 242 ICRALNYLHRVVGVCHR 258
>KSG2_ARATH (O23145) Shaggy-related protein kinase beta (EC 2.7.11.1)| (ASK-beta) Length = 431 Score = 203 bits (517), Expect = 1e-52 Identities = 94/136 (69%), Positives = 112/136 (82%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G N + +TISY AE V+GTGSFG+VFQAKCLET E VAIKKVLQD+RYKNRELQ+MR + Sbjct: 91 GLNDQKDKTISYRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQDKRYKNRELQIMRML 150 Query: 185 DHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQL 364 DHPNVV LKH FFSTT +DEL+LNLV+EYVPET+YR + Y+ NQ MPLIY++LY YQ+ Sbjct: 151 DHPNVVELKHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQHMPLIYIQLYTYQI 210 Query: 365 FRGLAYVHTVPGVCHR 412 R + Y+H V GVCHR Sbjct: 211 CRAMNYLHQVVGVCHR 226
>KSG4_ARATH (Q9FVS6) Shaggy-related protein kinase delta (EC 2.7.11.1)| (ASK-delta) Length = 420 Score = 200 bits (509), Expect = 1e-51 Identities = 92/136 (67%), Positives = 114/136 (83%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G+NG+ ++T+SY+AE VVGTGSFG+VFQAKC ETGE VAIKKVLQD+RYKNRELQ+M+ + Sbjct: 71 GRNGQSRQTVSYIAEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNRELQIMQML 130 Query: 185 DHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQL 364 DHPNVV LKH F+S T +E++LNLV+E+VPET+ R + YS NQ MPLIYVKLY YQ+ Sbjct: 131 DHPNVVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQI 190 Query: 365 FRGLAYVHTVPGVCHR 412 RGLAY+H G+CHR Sbjct: 191 CRGLAYLHNCCGLCHR 206
>KSG10_ARATH (Q39019) Shaggy-related protein kinase kappa (EC 2.7.11.1)| (ASK-kappa) (AtK-1) Length = 421 Score = 199 bits (506), Expect = 2e-51 Identities = 91/136 (66%), Positives = 114/136 (83%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G+NG+ ++T+SY++E VVGTGSFG+VFQAKC ETGE VAIKKVLQD+RYKNRELQ+M+ + Sbjct: 72 GRNGQSRQTVSYISEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNRELQIMQML 131 Query: 185 DHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQL 364 DHPN V+LKH FFS T +E++LNLV+E+VPET+ RV + YS NQ MPLIYVKLY YQ+ Sbjct: 132 DHPNAVALKHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQI 191 Query: 365 FRGLAYVHTVPGVCHR 412 R LAY+H G+CHR Sbjct: 192 CRALAYIHNSFGLCHR 207
>GSK3B_RAT (P18266) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) (Factor A) (FA) Length = 420 Score = 174 bits (441), Expect = 9e-44 Identities = 80/137 (58%), Positives = 111/137 (81%), Gaps = 1/137 (0%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G+ + + +SY +V+G GSFG+V+QAK ++GE VAIKKVLQD+R+KNRELQ+MR + Sbjct: 45 GQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKL 104 Query: 185 DHPNVVSLKHCFFST-TSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 DH N+V L++ F+S+ +DE++LNLV++YVPET+YRV +HYS A Q +P+IYVKLYMYQ Sbjct: 105 DHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQ 164 Query: 362 LFRGLAYVHTVPGVCHR 412 LFR LAY+H+ G+CHR Sbjct: 165 LFRSLAYIHSF-GICHR 180
>GSK3B_MOUSE (Q9WV60) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 174 bits (441), Expect = 9e-44 Identities = 80/137 (58%), Positives = 111/137 (81%), Gaps = 1/137 (0%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G+ + + +SY +V+G GSFG+V+QAK ++GE VAIKKVLQD+R+KNRELQ+MR + Sbjct: 45 GQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKL 104 Query: 185 DHPNVVSLKHCFFST-TSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 DH N+V L++ F+S+ +DE++LNLV++YVPET+YRV +HYS A Q +P+IYVKLYMYQ Sbjct: 105 DHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQ 164 Query: 362 LFRGLAYVHTVPGVCHR 412 LFR LAY+H+ G+CHR Sbjct: 165 LFRSLAYIHSF-GICHR 180
>GSK3B_HUMAN (P49841) Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3| beta) Length = 420 Score = 174 bits (441), Expect = 9e-44 Identities = 80/137 (58%), Positives = 111/137 (81%), Gaps = 1/137 (0%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G+ + + +SY +V+G GSFG+V+QAK ++GE VAIKKVLQD+R+KNRELQ+MR + Sbjct: 45 GQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKL 104 Query: 185 DHPNVVSLKHCFFST-TSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 DH N+V L++ F+S+ +DE++LNLV++YVPET+YRV +HYS A Q +P+IYVKLYMYQ Sbjct: 105 DHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQ 164 Query: 362 LFRGLAYVHTVPGVCHR 412 LFR LAY+H+ G+CHR Sbjct: 165 LFRSLAYIHSF-GICHR 180
>GSK3A_RAT (P18265) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) (Factor A) (FA) Length = 483 Score = 167 bits (424), Expect = 8e-42 Identities = 79/137 (57%), Positives = 109/137 (79%), Gaps = 1/137 (0%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G+ E + ++Y +V+G GSFG+V+QA+ ET E VAIKKVLQD+R+KNRELQ+MR + Sbjct: 108 GQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKL 167 Query: 185 DHPNVVSLKHCFFST-TSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 DH N+V L++ F+S+ +DEL+LNLV+EYVPET+YRV +H++ A +P+IYVK+YMYQ Sbjct: 168 DHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLIIPIIYVKVYMYQ 227 Query: 362 LFRGLAYVHTVPGVCHR 412 LFR LAY+H+ GVCHR Sbjct: 228 LFRSLAYIHS-QGVCHR 243
>GSK3A_HUMAN (P49840) Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3| alpha) Length = 483 Score = 167 bits (424), Expect = 8e-42 Identities = 78/137 (56%), Positives = 109/137 (79%), Gaps = 1/137 (0%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G+ E + ++Y +V+G GSFG+V+QA+ ET E VAIKKVLQD+R+KNRELQ+MR + Sbjct: 108 GQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKL 167 Query: 185 DHPNVVSLKHCFFST-TSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 DH N+V L++ F+S+ +DEL+LNLV+EYVPET+YRV +H++ A +P++YVK+YMYQ Sbjct: 168 DHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQ 227 Query: 362 LFRGLAYVHTVPGVCHR 412 LFR LAY+H+ GVCHR Sbjct: 228 LFRSLAYIHS-QGVCHR 243
>SGG_DROME (P18431) Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white 3)| Length = 1067 Score = 166 bits (420), Expect = 2e-41 Identities = 76/137 (55%), Positives = 108/137 (78%), Gaps = 1/137 (0%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G+ + + +SY +V+G GSFG+VFQAK +TGE VAIKKVLQDRR+KNRELQ+MR + Sbjct: 596 GQGTDRVQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKL 655 Query: 185 DHPNVVSLKHCFFST-TSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 +H N+V L + F+S+ RDE+FLNLV+EY+PET+Y+V + Y+ Q +P+ +++LYMYQ Sbjct: 656 EHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQ 715 Query: 362 LFRGLAYVHTVPGVCHR 412 LFR LAY+H++ G+CHR Sbjct: 716 LFRSLAYIHSL-GICHR 731
>GSK3H_DROME (P83101) Putative glycogen synthase kinase-3 homolog (EC 2.7.11.26)| (GSK-3) (Protein gasket) Length = 501 Score = 156 bits (394), Expect = 2e-38 Identities = 75/128 (58%), Positives = 101/128 (78%), Gaps = 1/128 (0%) Frame = +2 Query: 32 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSMDHPNVVSLK 211 ISY +VVG GSFG+VFQAK + + E VAIKKVLQDRR+KNRELQ+MR + H N+++LK Sbjct: 31 ISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMRKLRHDNIITLK 90 Query: 212 HCFFST-TSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 FFS+ RDE++LNLVME++PETLY+V + Y+ A Q +P+ +V+LYMYQL R + Y+H Sbjct: 91 WFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMGYLH 150 Query: 389 TVPGVCHR 412 ++ G CHR Sbjct: 151 SL-GFCHR 157
>GSK3H_DICDI (P51136) Glycogen synthase kinase-3 homolog (EC 2.7.11.26) (GSK-3)| Length = 467 Score = 154 bits (390), Expect = 7e-38 Identities = 73/127 (57%), Positives = 102/127 (80%) Frame = +2 Query: 32 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSMDHPNVVSLK 211 + Y+ E V+G GSFG+V QA +T E VAIKKVLQD+RYKNRELQ+M+ ++H N+VSLK Sbjct: 54 VCYITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLK 113 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + F+ T+ DE++LNLV+EYVP+T+YRV +HYS + Q +P I+VKLY+YQL R + Y+H+ Sbjct: 114 NSFY-TSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHS 172 Query: 392 VPGVCHR 412 + G+CHR Sbjct: 173 L-GICHR 178
>MRK1_YEAST (P50873) Serine/threonine-protein kinase MRK1 (EC 2.7.11.1)| Length = 501 Score = 148 bits (373), Expect = 7e-36 Identities = 66/127 (51%), Positives = 91/127 (71%) Frame = +2 Query: 32 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSMDHPNVVSLK 211 ISY VVG GSFG+V +ET + VAIKKVLQDRRYKNREL+ M+ + HPN V L+ Sbjct: 162 ISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQ 221 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + F+ DE++LNLV++Y+P++LY+ L+H+ N +MP + +K Y YQLF+ L Y+H Sbjct: 222 YYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHN 281 Query: 392 VPGVCHR 412 VP +CHR Sbjct: 282 VPRICHR 288
>GSK3_SCHPO (Q10452) Protein kinase gsk3 (EC 2.7.11.1) (Protein kinaae skp1)| Length = 387 Score = 145 bits (365), Expect = 6e-35 Identities = 70/137 (51%), Positives = 100/137 (72%), Gaps = 1/137 (0%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G GE K+ +SY + +VVG+GSFG+V Q +E+ AIK+VLQD+R+KNRELQ+MR M Sbjct: 22 GSTGEVKQ-LSYTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKNRELQIMRIM 80 Query: 185 DHPNVVSLKHCFFST-TSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 HPN+V L +++T + DE++LNLV+E++PET+YR + Y+ MP++ VKLY+YQ Sbjct: 81 KHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQ 140 Query: 362 LFRGLAYVHTVPGVCHR 412 L R LAY+H G+CHR Sbjct: 141 LLRSLAYIH-ASGICHR 156
>MDS1_YEAST (P38615) Serine/threonine-protein kinase MDS1/RIM11 (EC 2.7.11.1)| Length = 370 Score = 139 bits (349), Expect = 4e-33 Identities = 62/127 (48%), Positives = 91/127 (71%) Frame = +2 Query: 32 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSMDHPNVVSLK 211 IS+ VVG GSFG+VF ET E VAIKKVLQD+R+KNREL++M+ + H N++ LK Sbjct: 37 ISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLK 96 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + F+ S+DE++LNL++EY+P++LY+ L+H+ + M + +K YM+QLF+ L Y+H Sbjct: 97 YFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHH 156 Query: 392 VPGVCHR 412 VCHR Sbjct: 157 FANVCHR 163
>GSK31_SCHPO (Q9URT9) Protein kinase gsk31 (EC 2.7.11.1)| Length = 381 Score = 137 bits (345), Expect = 1e-32 Identities = 71/138 (51%), Positives = 101/138 (73%), Gaps = 2/138 (1%) Frame = +2 Query: 5 GKNGEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRSM 184 G GE K+TISY RV+G+GSFG+V QAK + T +A+K+VLQD+RYKNRELQ+MR++ Sbjct: 15 GTTGE-KKTISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKNRELQIMRAI 73 Query: 185 DHPNVVSLKHCFFST--TSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMY 358 HPN++ L FF T S+DE L L++EY+PET++ ++ Y+ + +P + +KLY + Sbjct: 74 SHPNIIKL-IAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAF 132 Query: 359 QLFRGLAYVHTVPGVCHR 412 QLFR LAY+H+ GVCHR Sbjct: 133 QLFRALAYLHST-GVCHR 149
>MCK1_YEAST (P21965) Protein kinase MCK1 (EC 2.7.11.1) (Meiosis and centromere| regulatory kinase) Length = 375 Score = 95.1 bits (235), Expect = 7e-20 Identities = 52/126 (41%), Positives = 77/126 (61%), Gaps = 5/126 (3%) Frame = +2 Query: 50 RVVGTGSFGIVFQAKCLETGET----VAIKKVLQDRRYKNRELQLMRSMDHPNVVSLKHC 217 R +G G+FG V QA + + AIKKV YK+RELQ++R DHPN+V L++ Sbjct: 39 RKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYF 98 Query: 218 FFSTTSRD-ELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 F + +D +++ +L ME +PETL + Y MPL +++LY YQ+ RG+ Y+H + Sbjct: 99 FTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGL 158 Query: 395 PGVCHR 412 GVCHR Sbjct: 159 -GVCHR 163
>KOM8_YEAST (Q12222) Probable serine/threonine-protein kinase YOL128C (EC| 2.7.11.1) Length = 375 Score = 76.3 bits (186), Expect = 3e-14 Identities = 44/126 (34%), Positives = 77/126 (61%), Gaps = 8/126 (6%) Frame = +2 Query: 56 VGTGSFGIVFQA----KCLETGETVAIKKVLQDRRYKNRELQLMRSMDHPNVVSLKHCFF 223 +G GSFG V Q+ +E AIK+V++ + ++ EL++++++ HPN+V+L+ F Sbjct: 47 IGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSPKVQSLELEILQNIRHPNLVTLEFFFE 106 Query: 224 S-TTSRDELFL---NLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 S T++D L N VMEY+P+TL + Y + +MP ++KLY +Q+ R L +H+ Sbjct: 107 SHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHS 166 Query: 392 VPGVCH 409 + +CH Sbjct: 167 M-SICH 171
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 71.6 bits (174), Expect = 8e-13 Identities = 43/125 (34%), Positives = 72/125 (57%), Gaps = 6/125 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPN 196 S+ +G G++G+V++AK TGETVA+KK+ D + RE+ L++ ++HPN Sbjct: 3 SFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHPN 62 Query: 197 VVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 +V L H T ++ L LV E++ + L R + + +PL VK Y++QL +GL Sbjct: 63 IVKL-HDVIHTENK----LYLVFEFLHQDLKRFMDSSTVTGISLPL--VKSYLFQLLQGL 115 Query: 377 AYVHT 391 A+ H+ Sbjct: 116 AFCHS 120
>MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (EC 2.7.11.24)| (MAP kinase 4) (AtMPK4) Length = 376 Score = 70.1 bits (170), Expect = 2e-12 Identities = 43/127 (33%), Positives = 72/127 (56%), Gaps = 6/127 (4%) Frame = +2 Query: 50 RVVGTGSFGIVFQAKCLETGETVAIKKV------LQDRRYKNRELQLMRSMDHPNVVSLK 211 R +G G++GIV A ETGE VAIKK+ + D + RE++L++ MDH NV+++K Sbjct: 47 RPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHENVIAVK 106 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + + +V E + L+++++ +NQ + + + ++YQL RGL YVH+ Sbjct: 107 DIIKPPQRENFNDVYIVYELMDTDLHQIIR----SNQPLTDDHCRFFLYQLLRGLKYVHS 162 Query: 392 VPGVCHR 412 V HR Sbjct: 163 A-NVLHR 168
>MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK2 (EC| 2.7.11.24) Length = 371 Score = 69.7 bits (169), Expect = 3e-12 Identities = 46/127 (36%), Positives = 70/127 (55%), Gaps = 6/127 (4%) Frame = +2 Query: 50 RVVGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNVVSLK 211 R VG G++GIV A ET E VAIKK+ D + RE++L+R MDH NV+S+K Sbjct: 41 RSVGRGAYGIVCAAVNAETREEVAIKKIGNAFDNRIDAKRTLREIKLLRHMDHENVMSIK 100 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + + +V E + L+++++ +NQ M + + ++YQL RGL YVH+ Sbjct: 101 DIIRPPQKENFNHVYIVSELMDTDLHQIIR----SNQPMTDDHCRYFVYQLLRGLKYVHS 156 Query: 392 VPGVCHR 412 V HR Sbjct: 157 A-NVLHR 162
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 68.2 bits (165), Expect = 9e-12 Identities = 42/130 (32%), Positives = 70/130 (53%), Gaps = 5/130 (3%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ-----DRRYKNRELQLMRSMDHPNVV 202 Y R +G G++G V K E+GE VAIK++ + D RE++ ++ ++H NV+ Sbjct: 4 YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVI 63 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 LK R+ L + EY+ E LY+++K + N+ P ++ MYQ+ +GLA+ Sbjct: 64 KLKEVI-----RENDHLYFIFEYMKENLYQLMK---DRNKLFPESVIRNIMYQILQGLAF 115 Query: 383 VHTVPGVCHR 412 +H G HR Sbjct: 116 IHK-HGFFHR 124
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 68.2 bits (165), Expect = 9e-12 Identities = 42/130 (32%), Positives = 70/130 (53%), Gaps = 5/130 (3%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ-----DRRYKNRELQLMRSMDHPNVV 202 Y R +G G++G V K E+GE VAIK++ + D RE++ ++ ++H NV+ Sbjct: 4 YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVI 63 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 LK R+ L + EY+ E LY+++K + N+ P ++ MYQ+ +GLA+ Sbjct: 64 KLKEVI-----RENDHLYFIFEYMKENLYQLMK---DRNKLFPESVIRNIMYQILQGLAF 115 Query: 383 VHTVPGVCHR 412 +H G HR Sbjct: 116 IHK-HGFFHR 124
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 67.4 bits (163), Expect = 1e-11 Identities = 37/118 (31%), Positives = 67/118 (56%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++AK ETG+ VA+KK+ D + RE+ L++ + HPN+V L Sbjct: 10 IGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRL--- 66 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 +E L LV E++ + L + + S +PL +K Y++QL +G+++ H+ Sbjct: 67 --LDVVHNERKLYLVFEFLSQDLKKYMD--STPGSELPLHLIKSYLFQLLQGVSFCHS 120
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 67.4 bits (163), Expect = 1e-11 Identities = 42/130 (32%), Positives = 70/130 (53%), Gaps = 5/130 (3%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ-----DRRYKNRELQLMRSMDHPNVV 202 Y + +G G++G V K E+GE VAIK++ + D RE++ ++ ++H NV+ Sbjct: 4 YTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVI 63 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 LK R+ L V EY+ E LY+++K + N+ P ++ MYQ+ +GLA+ Sbjct: 64 KLKEVI-----RENDHLYFVFEYMKENLYQLMK---DRNKLFPESVIRNIMYQILQGLAF 115 Query: 383 VHTVPGVCHR 412 +H G HR Sbjct: 116 IHK-HGFFHR 124
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 67.4 bits (163), Expect = 1e-11 Identities = 39/118 (33%), Positives = 69/118 (58%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++AK TGE VA+KK+ D + RE+ L++ ++HPN+V L Sbjct: 10 IGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + E L LV E++ + L + + ++A +PL +K Y++QL +GLA+ H+ Sbjct: 70 IHT-----ENKLYLVFEFLHQDLKKFMD--ASALTGLPLPLIKSYLFQLLQGLAFCHS 120
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 67.0 bits (162), Expect = 2e-11 Identities = 39/118 (33%), Positives = 69/118 (58%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++AK TGE VA+KK+ D + RE+ L++ ++HPN+V L Sbjct: 10 IGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + E L LV E++ + L + + ++A +PL +K Y++QL +GLA+ H+ Sbjct: 70 IHT-----ENKLYLVFEFLHQDLKKFMD--ASAVTGIPLPLIKSYLFQLLQGLAFCHS 120
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 67.0 bits (162), Expect = 2e-11 Identities = 39/118 (33%), Positives = 69/118 (58%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++AK TGE VA+KK+ D + RE+ L++ ++HPN+V L Sbjct: 10 IGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + E L LV E++ + L + + ++A +PL +K Y++QL +GLA+ H+ Sbjct: 70 IHT-----ENKLYLVFEFLHQDLKKFMD--ASALTGIPLPLIKSYLFQLLQGLAFCHS 120
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 67.0 bits (162), Expect = 2e-11 Identities = 39/118 (33%), Positives = 69/118 (58%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++AK TGE VA+KK+ D + RE+ L++ ++HPN+V L Sbjct: 10 IGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + E L LV E++ + L + + ++A +PL +K Y++QL +GLA+ H+ Sbjct: 70 IHT-----ENKLYLVFEFLHQDLKKFMD--ASALTGIPLPLIKSYLFQLLQGLAFCHS 120
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 66.6 bits (161), Expect = 3e-11 Identities = 41/130 (31%), Positives = 70/130 (53%), Gaps = 5/130 (3%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ-----DRRYKNRELQLMRSMDHPNVV 202 Y R +G G++G V + +E+GE +AIKK+ + + RE++ ++ ++H NVV Sbjct: 4 YTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANVV 63 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 LK R+ L + EY+ E LY+++K N+ P ++ MYQ+ +GLA+ Sbjct: 64 KLKEVI-----RENDHLYFIFEYMKENLYQLIK---ERNKLFPESAIRNIMYQILQGLAF 115 Query: 383 VHTVPGVCHR 412 +H G HR Sbjct: 116 IHK-HGFFHR 124
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 66.2 bits (160), Expect = 3e-11 Identities = 40/120 (33%), Positives = 71/120 (59%), Gaps = 8/120 (6%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++AK TGE VA+KK+ D + RE+ L++ ++HPN+V L Sbjct: 10 IGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNAN--QRMPLIYVKLYMYQLFRGLAYVHT 391 + ++L+L V E L++ LK + +A+ +PL +K Y++QL +GLA+ H+ Sbjct: 70 IH---TENKLYL------VFELLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAFCHS 120
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 65.9 bits (159), Expect = 4e-11 Identities = 38/118 (32%), Positives = 69/118 (58%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ TGE VA+KK+ D + RE+ L++ ++HPN+V L Sbjct: 10 IGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + E L LV E++ + L + + ++A +PL +K Y++QL +GLA+ H+ Sbjct: 70 IHT-----ENKLYLVFEFLHQDLKKFMD--ASALTGIPLPLIKSYLFQLLQGLAFCHS 120
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 65.1 bits (157), Expect = 7e-11 Identities = 40/126 (31%), Positives = 71/126 (56%), Gaps = 7/126 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG V++ ++ GETVA+KKV + K+ E+ L++++DHPN+V + Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGS 74 Query: 218 FFSTTSRDELFLNLVMEYVPE-TLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 + + S L +++EY +L + K++ ++P V LY +Q+ +GL Y+H Sbjct: 75 YQTNDS-----LCIILEYCENGSLRSICKNFG----KIPENLVALYTFQVLQGLLYLHN- 124 Query: 395 PGVCHR 412 GV HR Sbjct: 125 QGVIHR 130
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 65.1 bits (157), Expect = 7e-11 Identities = 39/130 (30%), Positives = 70/130 (53%), Gaps = 5/130 (3%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ-----DRRYKNRELQLMRSMDHPNVV 202 Y + +G G++G V + +E+GE +AIKK+ + + RE++ ++ ++H N+V Sbjct: 4 YTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIV 63 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 LK R+ L + EY+ E LY+++K N+ P ++ MYQ+ +GLA+ Sbjct: 64 KLKEVI-----RENDHLYFIFEYMKENLYQLIK---ERNKLFPESAIRNIMYQILQGLAF 115 Query: 383 VHTVPGVCHR 412 +H G HR Sbjct: 116 IHK-HGFFHR 124
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 65.1 bits (157), Expect = 7e-11 Identities = 39/130 (30%), Positives = 70/130 (53%), Gaps = 5/130 (3%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ-----DRRYKNRELQLMRSMDHPNVV 202 Y + +G G++G V + +E+GE +AIKK+ + + RE++ ++ ++H N+V Sbjct: 4 YTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIV 63 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 LK R+ L + EY+ E LY+++K N+ P ++ MYQ+ +GLA+ Sbjct: 64 KLKEVI-----RENDHLYFIFEYMKENLYQLIK---ERNKLFPESAIRNIMYQILQGLAF 115 Query: 383 VHTVPGVCHR 412 +H G HR Sbjct: 116 IHK-HGFFHR 124
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 64.7 bits (156), Expect = 1e-10 Identities = 40/118 (33%), Positives = 69/118 (58%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ ETGE VA+KK+ D + RE+ L++ ++HPN+V L Sbjct: 10 IGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + E L LV E++ + L + + SN + + L VK Y++QL +GLA+ H+ Sbjct: 70 IHT-----ENKLYLVFEFLNQDLKKFMDG-SNIS-GISLALVKSYLFQLLQGLAFCHS 120
>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC 2.7.11.24)| (MAP kinase 5) (AtMPK5) Length = 376 Score = 64.3 bits (155), Expect = 1e-10 Identities = 39/127 (30%), Positives = 70/127 (55%), Gaps = 6/127 (4%) Frame = +2 Query: 50 RVVGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNVVSLK 211 R +G G++G V A ET E +AIKK+ + D + RE++L+R ++H NVV +K Sbjct: 47 RPIGRGAYGFVCAAVDSETHEEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIK 106 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 D + + +V E + L+++++ +NQ + + + ++YQ+ RGL Y+H+ Sbjct: 107 DIIRPPKKEDFVDVYIVFELMDTDLHQIIR----SNQSLNDDHCQYFLYQILRGLKYIHS 162 Query: 392 VPGVCHR 412 V HR Sbjct: 163 A-NVLHR 168
>MPK6_ARATH (Q39026) Mitogen-activated protein kinase homolog 6 (EC 2.7.11.24)| (MAP kinase 6) (AtMPK6) Length = 395 Score = 63.9 bits (154), Expect = 2e-10 Identities = 38/125 (30%), Positives = 68/125 (54%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNVVSLKHC 217 +G G++GIV A ET E+VAIKK+ D + RE++L+R MDH N+V+++ Sbjct: 69 IGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDI 128 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 + + E + L+++++ +NQ + + + ++YQ+ RGL Y+H+ Sbjct: 129 IPPPLRNAFNDVYIAYELMDTDLHQIIR----SNQALSEEHCQYFLYQILRGLKYIHSA- 183 Query: 398 GVCHR 412 V HR Sbjct: 184 NVLHR 188
>MMK1_MEDSA (Q07176) Mitogen-activated protein kinase homolog MMK1 (EC| 2.7.11.24) (MAP kinase MSK7) (MAP kinase ERK1) Length = 387 Score = 63.9 bits (154), Expect = 2e-10 Identities = 41/125 (32%), Positives = 68/125 (54%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNVVSLKHC 217 +G G++GIV A ET E VA+KK+ D + RE++L+R MDH NVV+++ Sbjct: 61 IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRD- 119 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 + E+F ++ + Y E + L +NQ + + + ++YQ+ RGL Y+H+ Sbjct: 120 -IVPPPQREVFNDVYIAY--ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSA- 175 Query: 398 GVCHR 412 V HR Sbjct: 176 NVLHR 180
>MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (PMEK1) Length = 384 Score = 63.9 bits (154), Expect = 2e-10 Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 8/133 (6%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNR--------ELQLMRSMDHP 193 Y+ + +G G++GIV + ET E VAIKK+ + ++NR EL+L+R + H Sbjct: 32 YVPIKPIGRGAYGIVCSSVNRETNEKVAIKKI--NNAFENRIDALRTLRELKLLRHLRHE 89 Query: 194 NVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRG 373 NV++LK R + LV E + L++++K ++Q + + + +++QL RG Sbjct: 90 NVIALKDVMMPIQRRSFKDVYLVYELMDTDLHQIIK----SSQTLSNDHCQYFLFQLLRG 145 Query: 374 LAYVHTVPGVCHR 412 L Y+H+ + HR Sbjct: 146 LKYLHSA-NILHR 157
>MAPK_PEA (Q06060) Mitogen-activated protein kinase homolog D5 (EC 2.7.11.24)| Length = 394 Score = 63.5 bits (153), Expect = 2e-10 Identities = 41/125 (32%), Positives = 68/125 (54%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNVVSLKHC 217 +G G++GIV A ET E VA+KK+ D + RE++L+R MDH NVV+++ Sbjct: 68 IGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLREIKLVRHMDHENVVAIRD- 126 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 + E+F ++ + Y E + L +NQ + + + ++YQ+ RGL Y+H+ Sbjct: 127 -IVPPPQREVFNDVYIAY--ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSA- 182 Query: 398 GVCHR 412 V HR Sbjct: 183 NVLHR 187
>CDK9_CAEEL (Q9TVL3) Probable cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 478 Score = 63.5 bits (153), Expect = 2e-10 Identities = 41/122 (33%), Positives = 63/122 (51%), Gaps = 11/122 (9%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSL-KH 214 +G G+FG VF+A+C TG VA+KK+L + + RE++++ + HPN+ L + Sbjct: 91 IGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEV 150 Query: 215 CFFSTT----SRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 C +T S+D LVM L +L SN RM L+++K M L GL Sbjct: 151 CSAKSTGTTGSKDRATFYLVMALCAHDLAGLL---SNPKIRMSLVHIKTMMKHLMSGLNK 207 Query: 383 VH 388 +H Sbjct: 208 LH 209
>STY1_SCHPO (Q09892) Mitogen-activated protein kinase sty1 (EC 2.7.11.24) (MAP| kinase sty1) (MAP kinase spc1) Length = 349 Score = 63.5 bits (153), Expect = 2e-10 Identities = 45/136 (33%), Positives = 71/136 (52%), Gaps = 8/136 (5%) Frame = +2 Query: 29 TISYMAERVVGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSM 184 T Y + +G G+FG+V AK TG VA+KK VL R Y REL+L++ + Sbjct: 17 TTRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTY--RELKLLKHL 74 Query: 185 DHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQL 364 H N++SL F S + V E + L+R+L ++ + +++ ++YQ+ Sbjct: 75 RHENIISLSDIFISPFED----IYFVTELLGTDLHRLL-----TSRPLETQFIQYFLYQI 125 Query: 365 FRGLAYVHTVPGVCHR 412 RGL +VH+ GV HR Sbjct: 126 LRGLKFVHSA-GVIHR 140
>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3 (EC| 2.7.11.24) (P43) Length = 372 Score = 63.5 bits (153), Expect = 2e-10 Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 8/133 (6%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNR--------ELQLMRSMDHP 193 Y+ + +G G++GIV + ET E VAIKK+ + ++NR EL+L+R + H Sbjct: 32 YVPIKPIGRGAYGIVCSSVNRETNEKVAIKKI--NNAFENRIDALRTLRELKLLRHLRHE 89 Query: 194 NVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRG 373 NV++LK R + LV E + L++++K ++Q + + + +++QL RG Sbjct: 90 NVIALKDVMMPIHRRSFKDVYLVYELMDTDLHQIIK----SSQTLSNDHCQYFLFQLLRG 145 Query: 374 LAYVHTVPGVCHR 412 L Y+H+ + HR Sbjct: 146 LKYLHSA-NILHR 157
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 63.2 bits (152), Expect = 3e-10 Identities = 38/118 (32%), Positives = 65/118 (55%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ T ET+A+KK+ ++ + RE+ L++ M H N+V L+ Sbjct: 10 IGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSNIVKLQDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 S E L LV EY+ L + + S + L +K Y+YQ+ RG+AY H+ Sbjct: 70 VHS-----EKRLYLVFEYLDLDLKKHMD--STPDFSKDLHMIKTYLYQILRGIAYCHS 120
>MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (EC 2.7.11.24)| (MAP kinase 2) (AtMPK2) Length = 376 Score = 63.2 bits (152), Expect = 3e-10 Identities = 40/131 (30%), Positives = 71/131 (54%), Gaps = 6/131 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNV 199 Y+ + +G G++G+V + E+ E VAIKK+ D REL+L+R + H NV Sbjct: 32 YVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRHENV 91 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+LK + R + LV E + L++++K ++Q + + + +++QL RGL Sbjct: 92 VALKDVMMANHKRSFKDVYLVYELMDTDLHQIIK----SSQVLSNDHCQYFLFQLLRGLK 147 Query: 380 YVHTVPGVCHR 412 Y+H+ + HR Sbjct: 148 YIHSA-NILHR 157
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 62.8 bits (151), Expect = 4e-10 Identities = 38/132 (28%), Positives = 74/132 (56%), Gaps = 7/132 (5%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKK------VLQDRRYKNRELQLMRSMDHPNV 199 Y +G G++G+V A+ TG+ VAIKK V+ + + REL++++ H N+ Sbjct: 54 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNI 113 Query: 200 VSLKHCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 +++K T E + +V++ + L++++ +++Q + L +V+ ++YQL RGL Sbjct: 114 IAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII----HSSQPLTLEHVRYFLYQLLRGL 169 Query: 377 AYVHTVPGVCHR 412 Y+H+ V HR Sbjct: 170 KYMHSAQ-VIHR 180
>MK07_MOUSE (Q9WVS8) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase) Length = 806 Score = 62.8 bits (151), Expect = 4e-10 Identities = 38/132 (28%), Positives = 74/132 (56%), Gaps = 7/132 (5%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKK------VLQDRRYKNRELQLMRSMDHPNV 199 Y +G G++G+V A+ TG+ VAIKK V+ + + REL++++ H N+ Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNI 114 Query: 200 VSLKHCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 +++K T E + +V++ + L++++ +++Q + L +V+ ++YQL RGL Sbjct: 115 IAIKDILKPTVPYGEFRSVYVVLDLMESDLHQII----HSSQPLTLEHVRYFLYQLLRGL 170 Query: 377 AYVHTVPGVCHR 412 Y+H+ V HR Sbjct: 171 KYMHSAQ-VIHR 181
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 62.8 bits (151), Expect = 4e-10 Identities = 43/132 (32%), Positives = 68/132 (51%), Gaps = 7/132 (5%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNV 199 Y + VG+G++G V A TG VAIKK+ + + REL+L++ M H NV Sbjct: 27 YQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86 Query: 200 VSLKHCFFSTTSRDELF-LNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 + L F S D+ LVM ++ L +++KH + + R ++ +YQ+ +GL Sbjct: 87 IGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLMKHETLSEDR-----IQFLVYQMLKGL 141 Query: 377 AYVHTVPGVCHR 412 Y+H GV HR Sbjct: 142 KYIHAA-GVIHR 152
>NTF4_TOBAC (Q40532) Mitogen-activated protein kinase homolog NTF4 (EC| 2.7.11.24) (P45) Length = 393 Score = 62.8 bits (151), Expect = 4e-10 Identities = 41/125 (32%), Positives = 67/125 (53%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNVVSLKHC 217 +G G++GIV A ET E VAIKK+ D + RE++L+R MDH N+V+++ Sbjct: 66 IGKGAYGIVCSALNSETNEHVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDI 125 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 + E F ++ + Y E + L +NQ + + + ++YQ+ RGL Y+H+ Sbjct: 126 I--PPPQREAFNDVYIAY--ELMDTDLHQIIRSNQGLSEEHCQYFLYQILRGLKYIHSA- 180 Query: 398 GVCHR 412 V HR Sbjct: 181 NVLHR 185
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 62.4 bits (150), Expect = 5e-10 Identities = 38/118 (32%), Positives = 66/118 (55%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ T ET+A+KK+ ++ + RE+ L++ M H N+V L+ Sbjct: 10 IGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHGNIVRLQDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 S E L LV EY+ L + + +Q L VK+++YQ+ RG+AY H+ Sbjct: 70 VHS-----EKRLYLVFEYLDLDLKKHMDSCPEFSQDPRL--VKMFLYQILRGIAYCHS 120
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 62.4 bits (150), Expect = 5e-10 Identities = 39/124 (31%), Positives = 65/124 (52%), Gaps = 6/124 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNV 199 Y E +G G++G+V++A+ T ET+A+KK+ ++ + RE+ L++ M H N+ Sbjct: 4 YEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHHGNI 63 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V L S E + LV EY+ L + + + LI K Y+YQ+ RG+A Sbjct: 64 VRLHDVIHS-----EKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLI--KSYLYQILRGVA 116 Query: 380 YVHT 391 Y H+ Sbjct: 117 YCHS 120
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 62.4 bits (150), Expect = 5e-10 Identities = 39/117 (33%), Positives = 62/117 (52%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++GIV +AK ETGE VA+K++ D + RE+ L++ + HPN+V L Sbjct: 10 LGEGTYGIVNKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKELKHPNIVRLHDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + E L LV EY+ + L K+ + +K +MYQL +G+A+ H Sbjct: 70 IHT-----ERKLTLVFEYLDQDL---KKYLDECGGEISKPTIKSFMYQLLKGVAFCH 118
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 62.4 bits (150), Expect = 5e-10 Identities = 45/124 (36%), Positives = 67/124 (54%), Gaps = 7/124 (5%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKV-LQDRRYKN---RELQLMRSMDHPNVVS 205 Y +G G++G V++AK TG VA+KK+ L+D + RE+ L++ + HPNVVS Sbjct: 10 YQKLEKLGEGTYGKVYKAKEKATGRMVALKKIRLEDDGVPSTALREISLLKEVPHPNVVS 69 Query: 206 L---KHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 L HC + L LV EY+ + L K Y ++ + +K Y+YQL +GL Sbjct: 70 LFDVLHC--------QNRLYLVFEYLDQDL----KKYMDSVPALCPQLIKSYLYQLLKGL 117 Query: 377 AYVH 388 AY H Sbjct: 118 AYSH 121
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 62.0 bits (149), Expect = 6e-10 Identities = 40/131 (30%), Positives = 69/131 (52%), Gaps = 6/131 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNV 199 Y+ + +G G++G+V + ET E VAIKK+ D REL+L+R + H NV Sbjct: 32 YVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLRHVRHENV 91 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 ++LK + LV E + L++++K ++Q + + K +++QL RGL Sbjct: 92 IALKDVMLPANRSSFKDVYLVYELMDTDLHQIIK----SSQSLSDDHCKYFLFQLLRGLK 147 Query: 380 YVHTVPGVCHR 412 Y+H+ + HR Sbjct: 148 YLHSA-NILHR 157
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 61.6 bits (148), Expect = 8e-10 Identities = 42/132 (31%), Positives = 68/132 (51%), Gaps = 7/132 (5%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNV 199 Y + VG+G++G V A TG VAIKK+ + + REL+L++ M H NV Sbjct: 27 YQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86 Query: 200 VSLKHCFFSTTSRDELF-LNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 + L F + D+ LVM ++ L +++KH + + R ++ +YQ+ +GL Sbjct: 87 IGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHETLSEDR-----IQFLVYQMLKGL 141 Query: 377 AYVHTVPGVCHR 412 Y+H GV HR Sbjct: 142 KYIHAA-GVIHR 152
>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (MAP kinase 1) (AtMPK1) Length = 370 Score = 61.6 bits (148), Expect = 8e-10 Identities = 40/133 (30%), Positives = 71/133 (53%), Gaps = 8/133 (6%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN--------RELQLMRSMDHP 193 YM + +G G++G+V + +T E VAIKK+ Y+N REL+L+R + H Sbjct: 32 YMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKI--HNVYENRIDALRTLRELKLLRHLRHE 89 Query: 194 NVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRG 373 NV++LK + LV E + L++++K ++Q + + + +++QL RG Sbjct: 90 NVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIK----SSQVLSNDHCQYFLFQLLRG 145 Query: 374 LAYVHTVPGVCHR 412 L Y+H+ + HR Sbjct: 146 LKYIHSA-NILHR 157
>MPK3_ARATH (Q39023) Mitogen-activated protein kinase homolog 3 (EC 2.7.11.24)| (MAP kinase 3) (AtMPK3) Length = 370 Score = 61.2 bits (147), Expect = 1e-09 Identities = 35/125 (28%), Positives = 67/125 (53%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNVVSLKHC 217 +G G++GIV ET E VA+KK+ D + RE++L+R +DH N+++++ Sbjct: 44 IGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDAKRTLREIKLLRHLDHENIIAIRDV 103 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 R + + E + L+++++ +NQ + + + ++YQL RGL Y+H+ Sbjct: 104 VPPPLRRQFSDVYISTELMDTDLHQIIR----SNQSLSEEHCQYFLYQLLRGLKYIHSA- 158 Query: 398 GVCHR 412 + HR Sbjct: 159 NIIHR 163
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 61.2 bits (147), Expect = 1e-09 Identities = 41/132 (31%), Positives = 68/132 (51%), Gaps = 7/132 (5%) Frame = +2 Query: 17 EPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMR 178 +P+ Y+ R +G G++GIV++A TGE VAIKK+ R K RE+ L++ Sbjct: 6 DPRIVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQ 65 Query: 179 SM-DHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYM 355 DHPN++SL + RD + LV E++ L V++ + ++V+ Sbjct: 66 EFGDHPNIISLLDVIRAENDRD---IYLVFEFMDTDLNAVIR----KGGLLQDVHVRSIF 118 Query: 356 YQLFRGLAYVHT 391 YQL R ++H+ Sbjct: 119 YQLLRATRFLHS 130
>ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) Length = 415 Score = 60.8 bits (146), Expect = 1e-09 Identities = 38/131 (29%), Positives = 69/131 (52%), Gaps = 6/131 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKV------LQDRRYKNRELQLMRSMDHPNV 199 Y + +G G++G+V AK TGE VAIKK+ L+D + RE+ L+R H N+ Sbjct: 31 YSIVKCIGHGAYGVVCSAKDNLTGEKVAIKKISKAFDNLKDTKRTLREIHLLRHFKHENL 90 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 +S+K + + +V E + L++++ + Q + + + ++YQ+ RGL Sbjct: 91 ISIKDILKPNSKEQFEDVYIVSELMDTDLHQII----TSPQPLSDDHCQYFVYQMLRGLK 146 Query: 380 YVHTVPGVCHR 412 ++H+ V HR Sbjct: 147 HIHSA-NVLHR 156
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 60.8 bits (146), Expect = 1e-09 Identities = 40/118 (33%), Positives = 63/118 (53%), Gaps = 6/118 (5%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKH 214 VVG G++G+V + + ET E VAIKK + REL+++R++ N+V LK Sbjct: 18 VVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKE 77 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F R +L+ LV EYV + + +L+ N +P VK Y+YQL + + + H Sbjct: 78 AF---RRRGKLY--LVFEYVEKNMLELLEEMPNG---VPPEKVKSYIYQLIKAIHWCH 127
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 60.5 bits (145), Expect = 2e-09 Identities = 35/118 (29%), Positives = 66/118 (55%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ TG+ VA+KK+ D + RE+ L++ + HPN++ L Sbjct: 10 IGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKHPNIIKL--- 66 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 R++ L +V E++ + L R + S+ +PL VK Y+ QL G+++ H+ Sbjct: 67 -LDVVHREKK-LYMVFEFLTQDLKRHMD--SSPTSELPLPVVKSYLAQLLEGVSFCHS 120
>HOG1_CANAL (Q92207) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 377 Score = 60.5 bits (145), Expect = 2e-09 Identities = 44/134 (32%), Positives = 68/134 (50%), Gaps = 6/134 (4%) Frame = +2 Query: 29 TISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDH 190 T Y VG G+FG+V A TG+ VA+KKV++ + REL+L++ + H Sbjct: 20 TNRYTELNPVGMGAFGLVCSAVDRLTGQNVAVKKVMKPFSTSVLAKRTYRELKLLKHLKH 79 Query: 191 PNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFR 370 N+++L F S D F+N E L+R+L Q +++ + YQ+ R Sbjct: 80 ENLITLDDIFISPL-EDIYFVN---ELQGTDLHRLLNSRPLEKQ-----FIQYFTYQIMR 130 Query: 371 GLAYVHTVPGVCHR 412 GL Y+H+ GV HR Sbjct: 131 GLKYIHSA-GVIHR 143
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 60.1 bits (144), Expect = 2e-09 Identities = 42/125 (33%), Positives = 65/125 (52%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G VF+AK +T E VA+K+V D + RE+ L++ + H N+V L Sbjct: 10 IGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 S L LV E+ + L K++ + N + VK +MYQL +GLA+ H+ Sbjct: 70 LHSDKK-----LTLVFEFCDQDLK---KYFDSCNGDLDPEIVKSFMYQLLKGLAFCHS-R 120 Query: 398 GVCHR 412 V HR Sbjct: 121 NVLHR 125
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 3) Length = 651 Score = 60.1 bits (144), Expect = 2e-09 Identities = 43/145 (29%), Positives = 76/145 (52%), Gaps = 13/145 (8%) Frame = +2 Query: 17 EPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVL------------QDRRYKNR 160 E +I + ++G G+FG V+ L++GE +AIK+VL R Sbjct: 61 EEAPSIRWRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEE 120 Query: 161 ELQLMRSMDHPNVVSLKHCFFSTTSRDELFLNLVMEYVP-ETLYRVLKHYSNANQRMPLI 337 E+QL++++ HPN+V + T R+ LN++ME+VP ++ +L+ + + + + ++ Sbjct: 121 EVQLLKNLSHPNIVR-----YLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIM 175 Query: 338 YVKLYMYQLFRGLAYVHTVPGVCHR 412 Y K QL GL Y+H G+ HR Sbjct: 176 YTK----QLLLGLEYLHN-NGIMHR 195
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 60.1 bits (144), Expect = 2e-09 Identities = 35/125 (28%), Positives = 67/125 (53%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPN+V C Sbjct: 10 IGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIV----C 65 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 +D L L+ E++ + + L + Q + + VK Y+YQ+ +G+ + H+ Sbjct: 66 LLDVLMQDSR-LYLIFEFLSMDVKKYLDSIP-SGQYIDTMLVKSYLYQILQGIVFCHS-R 122 Query: 398 GVCHR 412 GV HR Sbjct: 123 GVLHR 127
>MK06_RAT (P27704) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (p55-MAPK) Length = 720 Score = 59.7 bits (143), Expect = 3e-09 Identities = 45/148 (30%), Positives = 77/148 (52%), Gaps = 15/148 (10%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVL----QDRRYKNRELQLMRSMDHPNVVS 205 YM + +G G G+VF A + + VAIKK++ Q ++ RE++++R +DH N+V Sbjct: 20 YMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVK 79 Query: 206 LKHCFFSTTSR--DEL-------FLNLVMEYVPETLYRVLKHYSNANQRMPLI--YVKLY 352 + + S+ D++ + +V EY+ L VL ++ PL+ + +L+ Sbjct: 80 VFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVL-------EQGPLLEEHARLF 132 Query: 353 MYQLFRGLAYVHTVPGVCHRGCETTKCF 436 MYQL RGL Y+H+ V HR + F Sbjct: 133 MYQLLRGLKYIHSA-NVLHRDLKPANLF 159
>MK06_MOUSE (Q61532) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) Length = 720 Score = 59.7 bits (143), Expect = 3e-09 Identities = 45/148 (30%), Positives = 77/148 (52%), Gaps = 15/148 (10%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVL----QDRRYKNRELQLMRSMDHPNVVS 205 YM + +G G G+VF A + + VAIKK++ Q ++ RE++++R +DH N+V Sbjct: 20 YMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVK 79 Query: 206 LKHCFFSTTSR--DEL-------FLNLVMEYVPETLYRVLKHYSNANQRMPLI--YVKLY 352 + + S+ D++ + +V EY+ L VL ++ PL+ + +L+ Sbjct: 80 VFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVL-------EQGPLLEEHARLF 132 Query: 353 MYQLFRGLAYVHTVPGVCHRGCETTKCF 436 MYQL RGL Y+H+ V HR + F Sbjct: 133 MYQLLRGLKYIHSA-NVLHRDLKPANLF 159
>MK06_HUMAN (Q16659) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) Length = 721 Score = 59.7 bits (143), Expect = 3e-09 Identities = 45/148 (30%), Positives = 77/148 (52%), Gaps = 15/148 (10%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVL----QDRRYKNRELQLMRSMDHPNVVS 205 YM + +G G G+VF A + + VAIKK++ Q ++ RE++++R +DH N+V Sbjct: 20 YMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVK 79 Query: 206 LKHCFFSTTSR--DEL-------FLNLVMEYVPETLYRVLKHYSNANQRMPLI--YVKLY 352 + + S+ D++ + +V EY+ L VL ++ PL+ + +L+ Sbjct: 80 VFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVL-------EQGPLLEEHARLF 132 Query: 353 MYQLFRGLAYVHTVPGVCHRGCETTKCF 436 MYQL RGL Y+H+ V HR + F Sbjct: 133 MYQLLRGLKYIHSA-NVLHRDLKPANLF 159
>MK12_BRARE (O42376) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Stress-activated protein kinase 3) Length = 363 Score = 59.7 bits (143), Expect = 3e-09 Identities = 45/134 (33%), Positives = 67/134 (50%), Gaps = 9/134 (6%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSMDHP 193 Y + VGTG++G V A TG VAIKK + R Y REL+L++ M H Sbjct: 25 YKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPFQSDLFAKRAY--RELRLLKHMKHD 82 Query: 194 NVVSLKHCFFSTTSRDELF-LNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFR 370 NV+ L F + S D LVM ++ L +++K + +R V+ +YQ+ + Sbjct: 83 NVIGLVDVFTADLSLDRFHDFYLVMPFMGTDLGKLMKMERLSEER-----VQYLVYQMLK 137 Query: 371 GLAYVHTVPGVCHR 412 GL Y+H G+ HR Sbjct: 138 GLKYIHAA-GIIHR 150
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 59.3 bits (142), Expect = 4e-09 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKHC 217 +G GS+G+VF+ + +TG+ VAIKK L+ ++ RE+++++ + HPN+V+L Sbjct: 10 IGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F R + L+LV EY T+ L Y +P VK +Q + + + H Sbjct: 70 F-----RRKRRLHLVFEYCDHTVLHELDRYQRG---VPEHLVKSITWQTLQAVNFCH 118
>NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF6 (EC| 2.7.11.24) (P43) Length = 371 Score = 59.3 bits (142), Expect = 4e-09 Identities = 39/125 (31%), Positives = 67/125 (53%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNVVSLKHC 217 VG G++G+V A ET E VAIKK+ D + RE++L+ MDH N++ +K Sbjct: 44 VGRGAYGMVCCATNSETKEEVAIKKIGNAFENRIDAKRTLREIKLLSHMDHENIIKIKDI 103 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 + + +V E + L+++++ ++Q + + + ++YQL RGL YVH+ Sbjct: 104 VRPPDREEFNDVYIVYELMDTDLHQIIR----SSQALTDDHCQYFLYQLLRGLKYVHSA- 158 Query: 398 GVCHR 412 V HR Sbjct: 159 NVLHR 163
>HOG1_ZYGRO (O93982) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 380 Score = 59.3 bits (142), Expect = 4e-09 Identities = 45/127 (35%), Positives = 65/127 (51%), Gaps = 8/127 (6%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSMDHPNVVSLK 211 VG G+FG+V A G+ VAIKK VL R Y REL+L++ + H N++ L+ Sbjct: 29 VGMGAFGLVCSATDTLAGQPVAIKKIMKPFSTAVLAKRTY--RELKLLKHLRHENLICLQ 86 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 F S + V E L+R+L+ Q +V+ ++YQ+ RGL YVH+ Sbjct: 87 DIFLSPLED----IYFVTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGLKYVHS 137 Query: 392 VPGVCHR 412 GV HR Sbjct: 138 A-GVIHR 143
>MK13_RAT (Q9WTY9) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 59.3 bits (142), Expect = 4e-09 Identities = 44/135 (32%), Positives = 69/135 (51%), Gaps = 9/135 (6%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSMDH 190 +Y+A VG+G++G V A TGE VAIKK + R Y REL L++ M H Sbjct: 24 TYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAY--RELLLLKHMHH 81 Query: 191 PNVVSLKHCFFSTTS-RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLF 367 NV+ L + TS R+ LVM ++ L +++ + + V+ +YQ+ Sbjct: 82 ENVIGLLDVYTPATSVRNFQDFYLVMPFMQTDLQKIMGMEFSEEK------VQYLVYQML 135 Query: 368 RGLAYVHTVPGVCHR 412 +GL Y+H+ G+ HR Sbjct: 136 KGLKYIHSA-GIVHR 149
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 59.3 bits (142), Expect = 4e-09 Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++ K T ET+A+KK+ ++ + RE+ L++ M H N+V L+ Sbjct: 10 IGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQ-- 67 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 E + LV EY+ L KH ++ VK ++YQ+ RG+AY H+ Sbjct: 68 ---DVVHKEKCIYLVFEYLDLDL---KKHMDSSPDFKNHRIVKSFLYQILRGIAYCHS 119
>NEK7_MOUSE (Q9ES74) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 59.3 bits (142), Expect = 4e-09 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 8/142 (5%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKV----LQDRRYKN---RELQLMRSMDHP 193 ++ E+ +G G F V++A CL G VA+KKV L D + + +E+ L++ ++HP Sbjct: 33 NFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHP 92 Query: 194 NVVSLKHCFFSTTSRDELFLNLVMEYVPE-TLYRVLKHYSNANQRMPLIYVKLYMYQLFR 370 NV+ F LN+V+E L R++KH+ + +P V Y QL Sbjct: 93 NVIKYYASFIEDNE-----LNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCS 147 Query: 371 GLAYVHTVPGVCHRGCETTKCF 436 L ++H+ V HR + F Sbjct: 148 ALDHMHS-RRVMHRDIKPANVF 168
>NEK7_HUMAN (Q8TDX7) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 59.3 bits (142), Expect = 4e-09 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 8/142 (5%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKV----LQDRRYKN---RELQLMRSMDHP 193 ++ E+ +G G F V++A CL G VA+KKV L D + + +E+ L++ ++HP Sbjct: 33 NFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHP 92 Query: 194 NVVSLKHCFFSTTSRDELFLNLVMEYVPE-TLYRVLKHYSNANQRMPLIYVKLYMYQLFR 370 NV+ F LN+V+E L R++KH+ + +P V Y QL Sbjct: 93 NVIKYYASFIEDNE-----LNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCS 147 Query: 371 GLAYVHTVPGVCHRGCETTKCF 436 L ++H+ V HR + F Sbjct: 148 ALEHMHS-RRVMHRDIKPANVF 168
>HOG1_YEAST (P32485) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) (Osmosensing protein HOG1) Length = 435 Score = 58.9 bits (141), Expect = 5e-09 Identities = 45/127 (35%), Positives = 65/127 (51%), Gaps = 8/127 (6%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSMDHPNVVSLK 211 VG G+FG+V A T + VAIKK VL R Y REL+L++ + H N++ L+ Sbjct: 29 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTY--RELKLLKHLRHENLICLQ 86 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 F S + V E L+R+L+ Q +V+ ++YQ+ RGL YVH+ Sbjct: 87 DIFLSPLED----IYFVTELQGTDLHRLLQTRPLEKQ-----FVQYFLYQILRGLKYVHS 137 Query: 392 VPGVCHR 412 GV HR Sbjct: 138 A-GVIHR 143
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 58.9 bits (141), Expect = 5e-09 Identities = 35/117 (29%), Positives = 63/117 (53%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKHC 217 +G GS+G+VF+ + +TG+ VAIKK ++ ++ RE+++++ + HPN+V+L Sbjct: 10 IGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQLKHPNLVNLMEV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F R + L+LV EY T+ L Y +P VK ++Q + + + H Sbjct: 70 F-----RRKRKLHLVFEYCDHTVLNELDRYPRG---VPEHMVKSIIWQTLQAVNFCH 118
>MK12_HUMAN (P53778) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 58.9 bits (141), Expect = 5e-09 Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 7/126 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKHC 217 VG+G++G V A TG VAIKK+ + + REL+L++ M H NV+ L Sbjct: 33 VGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDV 92 Query: 218 FFSTTSRDELF-LNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 F + D+ LVM ++ L +++KH R ++ +YQ+ +GL Y+H Sbjct: 93 FTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDR-----IQFLVYQMLKGLRYIHAA 147 Query: 395 PGVCHR 412 G+ HR Sbjct: 148 -GIIHR 152
>MK13_MOUSE (Q9Z1B7) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 58.5 bits (140), Expect = 7e-09 Identities = 44/135 (32%), Positives = 69/135 (51%), Gaps = 9/135 (6%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSMDH 190 +Y+A VG+G++G V A TGE VAIKK + R Y REL L++ M H Sbjct: 24 TYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAY--RELLLLKHMHH 81 Query: 191 PNVVSLKHCFFSTTS-RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLF 367 NV+ L F +S R LVM ++ L +++ + ++ V+ +YQ+ Sbjct: 82 ENVIGLLDVFTPASSLRSFHDFYLVMPFMQTDLQKIMGMEFSEDK------VQYLVYQML 135 Query: 368 RGLAYVHTVPGVCHR 412 +GL Y+H+ G+ HR Sbjct: 136 KGLKYIHSA-GIVHR 149
>MK11_HUMAN (Q15759) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress-activated protein kinase 2) Length = 372 Score = 58.5 bits (140), Expect = 7e-09 Identities = 43/131 (32%), Positives = 68/131 (51%), Gaps = 10/131 (7%) Frame = +2 Query: 50 RVVGTGSFGIVFQAKCLETGETVAIKKV------LQDRRYKNRELQLMRSMDHPNVVSLK 211 R VG+G++G V A + VA+KK+ L R REL+L++ + H NV+ L Sbjct: 28 RPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLL 87 Query: 212 HCFFSTTSRDELF-LNLVMEYVPETLYRVLKHYSNANQRMPLI---YVKLYMYQLFRGLA 379 F TS ++ + LV + L ++K + A+Q L +V+ +YQL RGL Sbjct: 88 DVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQAGAHQGARLALDEHVQFLVYQLLRGLK 147 Query: 380 YVHTVPGVCHR 412 Y+H+ G+ HR Sbjct: 148 YIHSA-GIIHR 157
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 58.5 bits (140), Expect = 7e-09 Identities = 39/140 (27%), Positives = 75/140 (53%), Gaps = 13/140 (9%) Frame = +2 Query: 32 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNR------------ELQLM 175 IS+ +++G G+FG V+ L++GE +A+K+VL + ++ E++L+ Sbjct: 67 ISWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLL 126 Query: 176 RSMDHPNVVSLKHCFFSTTSRDELFLNLVMEYVP-ETLYRVLKHYSNANQRMPLIYVKLY 352 +++ HPN+V + T R++ LN+++E+VP ++ +L+ + P V+ Y Sbjct: 127 KNLSHPNIVR-----YLGTVREDDTLNILLEFVPGGSISSLLEKFG----PFPESVVRTY 177 Query: 353 MYQLFRGLAYVHTVPGVCHR 412 QL GL Y+H + HR Sbjct: 178 TRQLLLGLEYLHN-HAIMHR 196
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 58.5 bits (140), Expect = 7e-09 Identities = 35/123 (28%), Positives = 62/123 (50%), Gaps = 6/123 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNV 199 Y+ +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPNV Sbjct: 4 YLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNV 63 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V L E L LV E++ L + L + P++ VK Y+YQ+ G+ Sbjct: 64 VRLLDVLM-----QESKLYLVFEFLSMDLKKYLDSIPSGQFMDPML-VKSYLYQILEGIL 117 Query: 380 YVH 388 + H Sbjct: 118 FCH 120
>HOG1_DEBHA (Q9UV50) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 387 Score = 58.2 bits (139), Expect = 9e-09 Identities = 43/127 (33%), Positives = 66/127 (51%), Gaps = 8/127 (6%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSMDHPNVVSLK 211 VG G+FG+V A TG+ VA+KK VL R Y REL+L++ + H N+++L Sbjct: 29 VGMGAFGLVCSAIDKLTGQNVAVKKIMKPFLTSVLAKRTY--RELKLLKHLRHENLITLD 86 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 F S + V E L+R+L ++ + +++ + YQ+ RGL YVH+ Sbjct: 87 DIFLSPLED----IYFVTELQGTDLHRLL-----TSRPLEKQFIQYFTYQILRGLKYVHS 137 Query: 392 VPGVCHR 412 GV HR Sbjct: 138 A-GVIHR 143
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 58.2 bits (139), Expect = 9e-09 Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNV 199 +Y+ +G G++ VF+ + T VA+K++ + RE+ L++++ H N+ Sbjct: 141 TYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANI 200 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+L + S L LV EY+ L + L H N M + VK++M+QL RGLA Sbjct: 201 VTLHDLIHTDRS-----LTLVFEYLDSDLKQYLDHCGNL---MSMHNVKIFMFQLLRGLA 252 Query: 380 YVH 388 Y H Sbjct: 253 YCH 255
>MK04_HUMAN (P31152) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) Length = 557 Score = 58.2 bits (139), Expect = 9e-09 Identities = 45/137 (32%), Positives = 69/137 (50%), Gaps = 10/137 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKV-LQDRR---YKNRELQLMRSMDHPNVVSLKHCFF 223 +G G G+V A VA+KK+ L D R + RE++++R +DH N+V + Sbjct: 26 LGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMKHALREIKIIRRLDHDNIVKVYEVLG 85 Query: 224 --STTSRDELF----LNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYV 385 T + ELF +V EY+ L R+L+ + A + + KL+MYQL RGL Y+ Sbjct: 86 PKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLAEE-----HAKLFMYQLLRGLKYI 140 Query: 386 HTVPGVCHRGCETTKCF 436 H+ V HR + F Sbjct: 141 HSA-NVLHRDLKPANIF 156
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 58.2 bits (139), Expect = 9e-09 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKHC 217 +G GS+G+VF+ + +TG+ VAIK+ L+ ++ RE+++++ + HPN+VSL Sbjct: 10 IGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVSLLEV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F R + L+LV EY T+ L Y +P VK +Q + + + H Sbjct: 70 F-----RRKRRLHLVFEYCHHTVLHELDRYQRG---VPEPLVKNITWQTLQAVNFCH 118
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 58.2 bits (139), Expect = 9e-09 Identities = 35/123 (28%), Positives = 65/123 (52%), Gaps = 6/123 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNV 199 Y ++ +G G++G+V +A VA+KK+ Q+R RE+ ++ + HPNV Sbjct: 4 YEKKQQLGEGTYGVVCKAWDTVCNRYVALKKIKQEREDDGIPVTSVREIAVLLELKHPNV 63 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V L + ++ FL LV E+ E LY+ + + + ++P+ + +YQ+ +GLA Sbjct: 64 VDLYDIYL-----EDKFLYLVFEFCDEDLYQ----FMSRSSKIPINETRSIVYQILQGLA 114 Query: 380 YVH 388 + H Sbjct: 115 FCH 117
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 58.2 bits (139), Expect = 9e-09 Identities = 32/118 (27%), Positives = 63/118 (53%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPN+V C Sbjct: 10 IGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIV----C 65 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 +D L L+ E++ L + L + Q + + VK Y+YQ+ +G+ + H+ Sbjct: 66 LLDVLMQDSR-LYLIFEFLSMDLKKYLDSIP-SGQYIDTMLVKSYLYQILQGIVFCHS 121
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 58.2 bits (139), Expect = 9e-09 Identities = 34/124 (27%), Positives = 64/124 (51%), Gaps = 6/124 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNV 199 Y+ +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPN+ Sbjct: 4 YIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 VSL+ + L L+ E++ L + L Q M VK Y+YQ+ +G+ Sbjct: 64 VSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIP-PGQFMDSSLVKSYLYQILQGIV 117 Query: 380 YVHT 391 + H+ Sbjct: 118 FCHS 121
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 58.2 bits (139), Expect = 9e-09 Identities = 33/118 (27%), Positives = 62/118 (52%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPN+VSL+ Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + L L+ E++ L + L Q M VK Y+YQ+ +G+ + H+ Sbjct: 70 LMQDSR-----LYLIFEFLSMDLKKYLDSIP-PGQYMDSSLVKSYLYQILQGIVFCHS 121
>PMK1_CAEEL (Q17446) Mitogen-activated protein kinase pmk-1 (EC 2.7.11.24) (p38| MAP kinase 1) (Stress-activated protein kinase pmk-1) Length = 377 Score = 57.8 bits (138), Expect = 1e-08 Identities = 42/130 (32%), Positives = 68/130 (52%), Gaps = 11/130 (8%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKK-------VLQDRRYKNRELQLMRSMDHPNVVSLKH 214 +GTG++G V A+C +G VAIKK ++ RR REL+L+R M H N++ L Sbjct: 41 IGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARR-TYRELRLLRCMCHENIIDLLD 99 Query: 215 CFFSTTS----RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 F + D F++++M L +LK QR+ +++ +YQ+ RGL Y Sbjct: 100 VFTPNENVNDIEDVYFVSMLM---GADLSNILK-----IQRLNDDHIQFLVYQILRGLKY 151 Query: 383 VHTVPGVCHR 412 +H+ + HR Sbjct: 152 IHSA-DIIHR 160
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 57.8 bits (138), Expect = 1e-08 Identities = 37/120 (30%), Positives = 66/120 (55%), Gaps = 8/120 (6%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ T ET+A+KK+ ++ + RE+ L++ M H N+V L+ Sbjct: 10 IGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHGNIVRLQDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSN--ANQRMPLIYVKLYMYQLFRGLAYVHT 391 S E L LV EY+ L + + + + RM +K ++YQ+ RG+AY H+ Sbjct: 70 VHS-----EKRLYLVFEYLDLDLKKHMDSCPDFAKDPRM----IKRFLYQILRGIAYCHS 120
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 57.8 bits (138), Expect = 1e-08 Identities = 35/118 (29%), Positives = 64/118 (54%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ T ET+A+KK+ ++ + RE+ L++ M H N+V L+ Sbjct: 10 IGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 S E L LV EY+ L + + S+ +K+++YQ+ G+AY H+ Sbjct: 70 VHS-----EKRLYLVFEYLDLDLKKFMD--SSPEFAKDQRQIKMFLYQILCGIAYCHS 120
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 57.8 bits (138), Expect = 1e-08 Identities = 33/118 (27%), Positives = 62/118 (52%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPN+VSL+ Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + L L+ E++ L + L Q M VK Y+YQ+ +G+ + H+ Sbjct: 70 LMQDSR-----LYLIFEFLSMDLKKYLDSIP-PGQFMDSSLVKSYLYQILQGIVFCHS 121
>HOG1_CANGA (Q6FIU2) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 57.4 bits (137), Expect = 2e-08 Identities = 45/127 (35%), Positives = 64/127 (50%), Gaps = 8/127 (6%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSMDHPNVVSLK 211 VG G+FG+V A T + VAIKK VL R Y REL+L++ + H N++ L+ Sbjct: 29 VGMGAFGLVCSATDTLTNQQVAIKKIMKPFATAVLAKRTY--RELKLLKHLRHENLICLQ 86 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 F S + V E L+R+L+ Q +V+ + YQ+ RGL YVH+ Sbjct: 87 DIFLSPLED----IYFVTELQGTDLHRLLQTRPLEKQ-----FVQYFHYQILRGLKYVHS 137 Query: 392 VPGVCHR 412 GV HR Sbjct: 138 A-GVVHR 143
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 6/123 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNV 199 Y+ +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPNV Sbjct: 4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNV 63 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V L E L L+ E++ L + L + P++ VK Y+YQ+ G+ Sbjct: 64 VRLLDVLM-----QESRLYLIFEFLSMDLKKYLDSIPSGQYMDPML-VKSYLYQILEGIY 117 Query: 380 YVH 388 + H Sbjct: 118 FCH 120
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 6/123 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNV 199 Y+ +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPNV Sbjct: 4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNV 63 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V L E L L+ E++ L + L + P++ VK Y+YQ+ G+ Sbjct: 64 VRLLDVLM-----QESRLYLIFEFLSMDLKKYLDSIPSGQYMDPML-VKSYLYQILEGIY 117 Query: 380 YVH 388 + H Sbjct: 118 FCH 120
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 6/123 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNV 199 Y+ +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPNV Sbjct: 4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNV 63 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V L E L L+ E++ L + L + P++ VK Y+YQ+ G+ Sbjct: 64 VRLLDVLM-----QESRLYLIFEFLSMDLKKYLDSIPSGQYMDPML-VKSYLYQILEGIY 117 Query: 380 YVH 388 + H Sbjct: 118 FCH 120
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 6/123 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNV 199 Y+ +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPNV Sbjct: 4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNV 63 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V L E L L+ E++ L + L + P++ VK Y+YQ+ G+ Sbjct: 64 VRLLDVLM-----QESRLYLIFEFLSMDLKKYLDSIPSGQYMDPML-VKSYLYQILEGIY 117 Query: 380 YVH 388 + H Sbjct: 118 FCH 120
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 57.4 bits (137), Expect = 2e-08 Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKHC 217 +G GS+G+VF+ + +TG+ VAIK+ L+ ++ RE+++++ + HPN+V+L Sbjct: 10 IGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVNLLEV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F R + L+LV EY T+ L Y +P VK +Q + + + H Sbjct: 70 F-----RRKRRLHLVFEYCDHTVLHELDRYQRG---VPEPLVKNITWQTLQAVNFCH 118
>WIN1_SCHPO (O74304) MAP kinase kinase kinase win1 (EC 2.7.11.25)| Length = 1436 Score = 57.4 bits (137), Expect = 2e-08 Identities = 41/137 (29%), Positives = 76/137 (55%), Gaps = 9/137 (6%) Frame = +2 Query: 29 TISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNR--------ELQLMRSM 184 TI + ++G+GSFG V++A L+TG+ +A+K+V + +R E+ ++ Sbjct: 1117 TIRWQQGGLIGSGSFGTVYRAVNLDTGDLMAVKEVALHKPRISRPMIKRIKGEMLVLELF 1176 Query: 185 DHPNVVSLKHCFFSTTSRDELFLNLVMEYVP-ETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 DHPNVVS + R++ +N+ ME +L+ L++ ++ + +++Y+ Q Sbjct: 1177 DHPNVVSY---YGIEVHREK--VNIFMELCQGSSLFEFLRYGRIEDE----LVIQVYVLQ 1227 Query: 362 LFRGLAYVHTVPGVCHR 412 L GLAY+H+ GV H+ Sbjct: 1228 LLEGLAYIHSC-GVSHQ 1243
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 57.4 bits (137), Expect = 2e-08 Identities = 38/123 (30%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNV 199 +Y+ +G G++ VF+ + T VA+K++ + RE+ L++ + H N+ Sbjct: 120 TYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANI 179 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+L + S L LV EY+ L + L H N M + VK++M+QL RGLA Sbjct: 180 VTLHDLIHTDRS-----LTLVFEYLDSDLKQYLDHCGNL---MNMHNVKIFMFQLLRGLA 231 Query: 380 YVH 388 Y H Sbjct: 232 YCH 234
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 57.4 bits (137), Expect = 2e-08 Identities = 38/123 (30%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNV 199 +Y+ +G G++ VF+ + T VA+K++ + RE+ L++ + H N+ Sbjct: 120 TYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANI 179 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+L + S L LV EY+ L + L H N M + VK++M+QL RGLA Sbjct: 180 VTLHDLIHTDRS-----LTLVFEYLDSDLKQYLDHCGNL---MNMHNVKIFMFQLLRGLA 231 Query: 380 YVH 388 Y H Sbjct: 232 YCH 234
>HOG1_ASHGO (Q750A9) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 57.0 bits (136), Expect = 2e-08 Identities = 44/127 (34%), Positives = 65/127 (51%), Gaps = 8/127 (6%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSMDHPNVVSLK 211 VG G+FG+V A T + VAIKK VL R Y REL+L++ + H N++ L+ Sbjct: 29 VGMGAFGLVCSAVDTYTQQPVAIKKIMKPFSTAVLAKRTY--RELKLLKHLRHENLICLE 86 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 F S + V E L+R+L+ Q +++ ++YQ+ RGL YVH+ Sbjct: 87 DIFLSPLED----IYFVTELQGTDLHRLLQTRPLEKQ-----FLQYFLYQILRGLKYVHS 137 Query: 392 VPGVCHR 412 GV HR Sbjct: 138 A-GVIHR 143
>MK14C_DROME (P83100) Putative mitogen-activated protein kinase 14C (EC| 2.7.11.24) (MAP kinase p38c) Length = 356 Score = 57.0 bits (136), Expect = 2e-08 Identities = 38/131 (29%), Positives = 66/131 (50%), Gaps = 6/131 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVL------QDRRYKNRELQLMRSMDHPNV 199 Y R +G GSFG V + + T A+K+++ +D + RE++L++ M+H NV Sbjct: 20 YEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHMNHRNV 79 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 +SL + F + Y+ L H + ++RM +++ +YQ+ RGL Sbjct: 80 ISLLNVFHPPAHN---MMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILRGLK 136 Query: 380 YVHTVPGVCHR 412 Y+H+ GV HR Sbjct: 137 YIHSA-GVVHR 146
>CRK1_SCHPO (Q12126) Serine/threonine-protein kinase crk1 (EC 2.7.11.23)| (Mitotic catastrophe suppressor 6) Length = 335 Score = 57.0 bits (136), Expect = 2e-08 Identities = 40/126 (31%), Positives = 68/126 (53%), Gaps = 7/126 (5%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-------RELQLMRSMDHP 193 +Y+ ER VG G++ +VF + ET VAIKK+ + ++K+ RE++ +R H Sbjct: 10 TYVKERKVGEGTYAVVFLGRQKETNRRVAIKKI-KVGQFKDGIDISALREIKFLRESRHD 68 Query: 194 NVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRG 373 NV+ L FST S LN+++E++ L ++K Q ++K +M L RG Sbjct: 69 NVIELVD-VFSTKSN----LNIILEFLDSDLEMLIKDKFIVFQP---AHIKSWMVMLLRG 120 Query: 374 LAYVHT 391 L ++H+ Sbjct: 121 LHHIHS 126
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 57.0 bits (136), Expect = 2e-08 Identities = 40/125 (32%), Positives = 64/125 (51%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G VF+AK ET E VA+K+V D + RE+ L++ + H N+V L Sbjct: 10 IGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 S L LV E+ + L K++ + N + VK +++QL +GL + H+ Sbjct: 70 LHSDKK-----LTLVFEFCDQDLK---KYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS-R 120 Query: 398 GVCHR 412 V HR Sbjct: 121 NVLHR 125
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 57.0 bits (136), Expect = 2e-08 Identities = 40/125 (32%), Positives = 64/125 (51%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G VF+AK ET E VA+K+V D + RE+ L++ + H N+V L Sbjct: 10 IGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 S L LV E+ + L K++ + N + VK +++QL +GL + H+ Sbjct: 70 LHSDKK-----LTLVFEFCDQDLK---KYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS-R 120 Query: 398 GVCHR 412 V HR Sbjct: 121 NVLHR 125
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 57.0 bits (136), Expect = 2e-08 Identities = 40/125 (32%), Positives = 64/125 (51%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G VF+AK ET E VA+K+V D + RE+ L++ + H N+V L Sbjct: 10 IGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 S L LV E+ + L K++ + N + VK +++QL +GL + H+ Sbjct: 70 LHSDKK-----LTLVFEFCDQDLK---KYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS-R 120 Query: 398 GVCHR 412 V HR Sbjct: 121 NVLHR 125
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 57.0 bits (136), Expect = 2e-08 Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A T ET+A+KK+ ++ + RE+ L++ M+H N+V L Sbjct: 10 IGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNHGNIVRLHDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 S E + LV EY+ L + + + LI K Y+YQ+ G+AY H+ Sbjct: 70 VHS-----EKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLI--KSYLYQILHGVAYCHS 120
>CDKL3_RAT (Q9JM01) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIATRE) Length = 593 Score = 56.6 bits (135), Expect = 3e-08 Identities = 36/124 (29%), Positives = 63/124 (50%), Gaps = 5/124 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQD-----RRYKNRELQLMRSMDHPNVVSLKHCF 220 VG GS+G V + K +TG VAIK + + RE++ ++ H N+V+L F Sbjct: 10 VGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKIATREIKFLKQFRHENLVNLIEVF 69 Query: 221 FSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVPG 400 R + ++LV E++ T+ L+HY + + L + Y++Q+ R + Y+H Sbjct: 70 -----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRL---RKYLFQILRAIEYLHN-NN 120 Query: 401 VCHR 412 + HR Sbjct: 121 IIHR 124
>CDKL3_MOUSE (Q8BLF2) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 595 Score = 56.6 bits (135), Expect = 3e-08 Identities = 36/124 (29%), Positives = 63/124 (50%), Gaps = 5/124 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQD-----RRYKNRELQLMRSMDHPNVVSLKHCF 220 VG GS+G V + K +TG VAIK + + RE++ ++ H N+V+L F Sbjct: 10 VGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKIATREIKFLKQFRHENLVNLIEVF 69 Query: 221 FSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVPG 400 R + ++LV E++ T+ L+HY + + L + Y++Q+ R + Y+H Sbjct: 70 -----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRL---RKYLFQILRAIEYLHN-NN 120 Query: 401 VCHR 412 + HR Sbjct: 121 IIHR 124
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 56.6 bits (135), Expect = 3e-08 Identities = 39/117 (33%), Positives = 60/117 (51%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++GIV++A+ +T E VA+KKV D+ RE+ L+ + HPN+V LK Sbjct: 45 IGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEV 104 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + +F LVM Y + L +L+ N VK + Q+ RGL Y+H Sbjct: 105 VVG-NHLESIF--LVMGYCEQDLASLLE---NMPTPFSEAQVKCIVLQVLRGLQYLH 155
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 56.6 bits (135), Expect = 3e-08 Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 6/118 (5%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKH 214 ++G G++G+V++A TG+ VA+KKV DR + RE+ +++ + HPN+V+L Sbjct: 28 ILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQEIHHPNIVNLLD 87 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + L L+ EYV L + L+ A L K +YQL GL++ H Sbjct: 88 VICADGK-----LYLIFEYVDHDLKKALEKRGGAFTGTTL---KKIIYQLLEGLSFCH 137
>CDK9_CHICK (Q5ZKN1) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 56.6 bits (135), Expect = 3e-08 Identities = 39/120 (32%), Positives = 64/120 (53%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG VF+AK +TG+ VA+KKVL + + RE+++++ + H NVV+L Sbjct: 25 IGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 218 FFSTTS---RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + S R + + LV ++ L +L SN + + L +K M L GL Y+H Sbjct: 85 CRTKASPYNRCKGSIYLVFDFCEHDLAGLL---SNTHVKFTLSEIKKVMQMLLNGLYYIH 141
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 56.6 bits (135), Expect = 3e-08 Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 7/119 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ T ET+A+KK+ ++ + RE+ L++ M H N+V L+ Sbjct: 10 IGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRM-PLIYVKLYMYQLFRGLAYVHT 391 S E L LV EY+ L KH ++ + + VK+++YQ+ G+AY H+ Sbjct: 70 VHS-----EKRLYLVFEYLDLDL---KKHMDSSPEFVKDPRQVKMFLYQILCGIAYCHS 120
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 56.6 bits (135), Expect = 3e-08 Identities = 39/143 (27%), Positives = 74/143 (51%), Gaps = 13/143 (9%) Frame = +2 Query: 23 KRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNR------------EL 166 K I + +++G G+FG V+ L++GE +A+K+VL ++ E+ Sbjct: 63 KPPIRWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEV 122 Query: 167 QLMRSMDHPNVVSLKHCFFSTTSRDELFLNLVMEYVP-ETLYRVLKHYSNANQRMPLIYV 343 +L++++ HPN+V + T R++ LN+++E+VP ++ +L+ + P V Sbjct: 123 KLLKNLSHPNIVR-----YLGTVREDETLNILLEFVPGGSISSLLEKFG----AFPESVV 173 Query: 344 KLYMYQLFRGLAYVHTVPGVCHR 412 + Y QL GL Y+H + HR Sbjct: 174 RTYTNQLLLGLEYLHN-HAIMHR 195
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 56.6 bits (135), Expect = 3e-08 Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++ + TG+ V +KK+ + + RE+ L++ + HPN+VSL+ Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + L L+ E++ L + L Q M VK Y+YQ+ +G+ + H+ Sbjct: 70 LMQDSR-----LYLIFEFLSMDLKKYLDSIP-PGQYMDSSLVKSYLYQILQGIVFCHS 121
>CDKL3_HUMAN (Q8IVW4) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIAMRE) Length = 592 Score = 56.2 bits (134), Expect = 3e-08 Identities = 37/125 (29%), Positives = 66/125 (52%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDR------RYKNRELQLMRSMDHPNVVSLKHC 217 VG GS+G V + K TG+ VAI K+ +R + RE++ ++ H N+V+L Sbjct: 10 VGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLKQFHHENLVNLIEV 68 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 F R + ++LV E++ T+ L+HY + + L + Y++Q+ R + Y+H+ Sbjct: 69 F-----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRL---RKYLFQILRAIDYLHS-N 119 Query: 398 GVCHR 412 + HR Sbjct: 120 NIIHR 124
>MK13_HUMAN (O15264) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 365 Score = 56.2 bits (134), Expect = 3e-08 Identities = 42/135 (31%), Positives = 69/135 (51%), Gaps = 9/135 (6%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSMDH 190 +Y++ VG+G++G V A +GE VAIKK + R Y REL L++ M H Sbjct: 24 TYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAY--RELLLLKHMQH 81 Query: 191 PNVVSLKHCFFSTTS-RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLF 367 NV+ L F +S R+ LVM ++ L +++ + + ++ +YQ+ Sbjct: 82 ENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGMEFSEEK------IQYLVYQML 135 Query: 368 RGLAYVHTVPGVCHR 412 +GL Y+H+ GV HR Sbjct: 136 KGLKYIHSA-GVVHR 149
>PMK2_CAEEL (Q8MXI4) Mitogen-activated protein kinase pmk-2 (EC 2.7.11.24) (p38| MAP kinase 2) (Stress-activated protein kinase pmk-2) Length = 419 Score = 56.2 bits (134), Expect = 3e-08 Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 9/134 (6%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSMDHPNV 199 Y + + +G G++G+V A+ TG+ VAIKK + + REL+L+R++ H NV Sbjct: 49 YNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNV 108 Query: 200 VSLKHCFFSTTSRDELFLN---LVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFR 370 + + F T D LN V + L ++K QR+ ++L +YQ+ R Sbjct: 109 LEMIDVF--TPDPDASSLNNVYFVSVLMGSDLQNIMK-----IQRLTDEQIQLLIYQVLR 161 Query: 371 GLAYVHTVPGVCHR 412 GL Y+H+ G+ HR Sbjct: 162 GLKYIHSA-GIIHR 174
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 56.2 bits (134), Expect = 3e-08 Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 7/119 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ T ET+A+KK+ ++ + RE+ L++ M H N+V L+ Sbjct: 10 IGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRM-PLIYVKLYMYQLFRGLAYVHT 391 S E L LV EY+ L KH ++ + + VK+++YQ+ G+AY H+ Sbjct: 70 VHS-----EKRLYLVFEYLDLDL---KKHMDSSPEFVKDPRQVKMFLYQILCGIAYCHS 120
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 56.2 bits (134), Expect = 3e-08 Identities = 37/125 (29%), Positives = 66/125 (52%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDR------RYKNRELQLMRSMDHPNVVSLKHC 217 VG GS+G V + K TG+ VAI K+ +R + RE++ ++ H N+V+L Sbjct: 10 VGEGSYGTVMKCKHKNTGQIVAI-KIFYERPEQSVNKIAMREIKFLKQFHHENLVNLIEV 68 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 F R + ++LV E++ T+ L+HY + + L + Y++Q+ R + Y+H+ Sbjct: 69 F-----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRL---RKYLFQILRAIDYLHS-N 119 Query: 398 GVCHR 412 + HR Sbjct: 120 NIIHR 124
>JNK_SUBDO (Q966Y3) Stress-activated protein kinase JNK (EC 2.7.11.24)| Length = 361 Score = 56.2 bits (134), Expect = 3e-08 Identities = 42/126 (33%), Positives = 69/126 (54%), Gaps = 7/126 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVL---QDRRYKNR---ELQLMRSMDHPNVVSLKHC 217 +G+G+ G+V A T E +AIKK++ Q+ Y R EL+LM+ +DH N++ LK+ Sbjct: 28 IGSGAQGVVCSAFDTVTQEKIAIKKLVKPFQNETYAKRAFRELRLMKMVDHKNIIGLKNL 87 Query: 218 FFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 F S D+ + +VME + L RV+ + RM + +YQL G+ ++H+ Sbjct: 88 FTPAKSLDDFQDVYIVMELMDANLCRVI-GIELDHDRMSYL-----LYQLLCGIKHLHSA 141 Query: 395 PGVCHR 412 G+ HR Sbjct: 142 -GIIHR 146
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 56.2 bits (134), Expect = 3e-08 Identities = 34/114 (29%), Positives = 64/114 (56%), Gaps = 6/114 (5%) Frame = +2 Query: 68 SFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHCFFST 229 ++G+V++A+ +ET E +A+KK+ ++ + RE+ L++ M H N+V+LK Sbjct: 1 AYGVVYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLK-----D 55 Query: 230 TSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 E L LV EY+ L + + +Q + + VK+++ Q+ RG+AY H+ Sbjct: 56 VVHREKRLYLVFEYLDLDLKKHMDSCPEFSQDLHM--VKMFLCQILRGVAYCHS 107
>CDK9A_XENLA (Q4V862) Cell division protein kinase 9-A (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-A) Length = 376 Score = 56.2 bits (134), Expect = 3e-08 Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 13/124 (10%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG VF+AK +TG+ VA+KKVL + + RE+++++ + H NVV+L Sbjct: 25 IGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 218 FFSTTS-------RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 + S R + + LV ++ L +L SNA+ + L +K M L GL Sbjct: 85 CRTKVSPTANQYNRCKGTIFLVFDFCEHDLAGLL---SNAHVKFTLSEIKKVMQMLLNGL 141 Query: 377 AYVH 388 Y+H Sbjct: 142 YYIH 145
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 55.8 bits (133), Expect = 4e-08 Identities = 37/123 (30%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNV 199 +Y+ +G G++ VF+ + VA+K++ + RE+ L++++ H N+ Sbjct: 141 TYVKLDKLGEGTYATVFKGRSKLMENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANI 200 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+L + S L LV EY+ L + L H N M + VK++M+QL RGLA Sbjct: 201 VTLHDLIHTDRS-----LTLVFEYLDSDLKQYLDHCGNL---MSMHNVKIFMFQLLRGLA 252 Query: 380 YVH 388 Y H Sbjct: 253 YCH 255
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 55.8 bits (133), Expect = 4e-08 Identities = 38/127 (29%), Positives = 65/127 (51%), Gaps = 15/127 (11%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKH 214 ++G G++G V++A+ +TGE VA+KKV D + RE++++R + H +VV++K Sbjct: 732 IIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKE 791 Query: 215 CFFSTT-----SRDELFLNLVMEYVPETLYRVLK----HYSNANQRMPLIYVKLYMYQLF 367 +D+ LV EY+ L +L+ H+S ++K +M QL Sbjct: 792 IVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED-------HIKSFMKQLM 844 Query: 368 RGLAYVH 388 GL Y H Sbjct: 845 EGLEYCH 851
>MK13_PANTR (Q9N272) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) Length = 365 Score = 55.8 bits (133), Expect = 4e-08 Identities = 42/135 (31%), Positives = 69/135 (51%), Gaps = 9/135 (6%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKK--------VLQDRRYKNRELQLMRSMDH 190 +Y++ VG+G++G V A +GE VAIKK + R Y REL L++ M H Sbjct: 24 TYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAY--RELLLLKHMQH 81 Query: 191 PNVVSLKHCFFSTTS-RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLF 367 NV+ L F +S R+ LVM ++ L +++ + + ++ +YQ+ Sbjct: 82 ENVIGLLDVFTPASSLRNFHDFYLVMXFMQTDLQKIMXMEFSEEK------IQYLVYQML 135 Query: 368 RGLAYVHTVPGVCHR 412 +GL Y+H+ GV HR Sbjct: 136 KGLKYIHSA-GVVHR 149
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 55.8 bits (133), Expect = 4e-08 Identities = 43/134 (32%), Positives = 68/134 (50%), Gaps = 7/134 (5%) Frame = +2 Query: 32 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYK-------NRELQLMRSMDH 190 + Y + +G G+F V+ A+ L+TG++VAIK + ++R K RE+ MR + H Sbjct: 10 LRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRH 69 Query: 191 PNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFR 370 PN+V L H +T S+ + VME+V + S R + + Y QL R Sbjct: 70 PNIVEL-HEVMATKSK----IYFVMEHVKGG--ELFNKVSTGKLREDV--ARKYFQQLVR 120 Query: 371 GLAYVHTVPGVCHR 412 + + H+ GVCHR Sbjct: 121 AVDFCHS-RGVCHR 133
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 55.8 bits (133), Expect = 4e-08 Identities = 32/117 (27%), Positives = 61/117 (52%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++ TG+ VA+KK+ + + RE+ L++ + HPN+V C Sbjct: 10 IGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIV----C 65 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 +D L L+ E++ L + L + Q + + VK Y+YQ+ +G+ + H Sbjct: 66 LLDVLMQDSR-LYLIFEFLSMDLKKYLDSIP-SGQYLEAMLVKSYLYQILQGIIFCH 120
>CDK9_XENTR (Q6GLD8) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 376 Score = 55.8 bits (133), Expect = 4e-08 Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 13/124 (10%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG VF+AK +TG+ VA+KKVL + + RE+++++ + H NVV+L Sbjct: 25 IGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 218 FFSTTS-------RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 + S R + + LV ++ L +L SNA+ + L +K M L GL Sbjct: 85 CRTKISPTANQYNRCKGTIFLVFDFCEHDLAGLL---SNAHVKFTLSEIKKVMQMLLNGL 141 Query: 377 AYVH 388 Y+H Sbjct: 142 YYIH 145
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 55.8 bits (133), Expect = 4e-08 Identities = 33/124 (26%), Positives = 64/124 (51%), Gaps = 6/124 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNV 199 Y+ +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPN+ Sbjct: 4 YIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 VSL+ + L L+ E++ L + L Q M VK Y++Q+ +G+ Sbjct: 64 VSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIP-PGQFMDSSLVKSYLHQILQGIV 117 Query: 380 YVHT 391 + H+ Sbjct: 118 FCHS 121
>YP62_CAEEL (Q09437) Putative serine/threonine-protein kinase B0495.2 (EC| 2.7.11.1) Length = 719 Score = 55.5 bits (132), Expect = 6e-08 Identities = 35/131 (26%), Positives = 72/131 (54%), Gaps = 7/131 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------REL-QLMRSMDHPNVVSLKH 214 V G+FG+V++ K T E VA+K++ ++ + RE+ L+++ +HPN+V++K Sbjct: 362 VDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGNHPNIVNVKE 421 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 ++ D+++ + ME+V + +L S N+R + K + QL G+ ++H + Sbjct: 422 ILLG-SNMDKIY--MAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIEHMHKL 478 Query: 395 PGVCHRGCETT 427 + HR +T+ Sbjct: 479 -WILHRDLKTS 488
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 55.5 bits (132), Expect = 6e-08 Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%) Frame = +2 Query: 2 GGKNGEPKRTIS-YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------- 157 GG + KR Y+ V+G G++G+VF+A +TG TVAIKK+ + +YK Sbjct: 6 GGDDAGVKRVADRYLKREVLGEGTYGVVFKAVDTKTGNTVAIKKI-RLGKYKEGVNFTAL 64 Query: 158 RELQLMRSMDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLI 337 RE++L++ + N++ L F + L+LV E++ L V++ + N + Sbjct: 65 REIKLLKELKDSNIIELIDAFPYKGN-----LHLVFEFMETDLEAVIR---DRNIVLSPA 116 Query: 338 YVKLYMYQLFRGLAYVH 388 K Y+ + +GLA+ H Sbjct: 117 DTKSYIQMMLKGLAFCH 133
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 55.5 bits (132), Expect = 6e-08 Identities = 36/126 (28%), Positives = 65/126 (51%), Gaps = 14/126 (11%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKH 214 ++G G++G V++A+ +TGE VA+KKV D + RE++++R + H +++++K Sbjct: 710 IIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKE 769 Query: 215 CFFSTT-----SRDELFLNLVMEYVPETLYRVLKH---YSNANQRMPLIYVKLYMYQLFR 370 +D+ LV EY+ L +L+ + N N ++K +M QL Sbjct: 770 IVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNEN------HIKSFMRQLME 823 Query: 371 GLAYVH 388 GL Y H Sbjct: 824 GLDYCH 829
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 55.5 bits (132), Expect = 6e-08 Identities = 40/125 (32%), Positives = 63/125 (50%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G VF+AK ET E VA+K+V D + RE+ L++ + H N+V L Sbjct: 10 IGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 S L LV E+ + L K++ + N + VK ++QL +GL + H+ Sbjct: 70 LHSDKK-----LTLVFEFCDQDLK---KYFDSCNGDLDPEIVKSLLFQLLKGLGFCHS-R 120 Query: 398 GVCHR 412 V HR Sbjct: 121 NVLHR 125
>CDK9_RAT (Q641Z4) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 55.5 bits (132), Expect = 6e-08 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG VF+AK +TG+ VA+KKVL + + RE+++++ + H NVV+L Sbjct: 25 IGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 218 FFSTTS---RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + S R + + LV ++ L +L SN + L +K M L GL Y+H Sbjct: 85 CRTKASPYNRCKGSIYLVFDFCEHDLAGLL---SNVLVKFTLSEIKRVMQMLLNGLYYIH 141
>CDK9_MOUSE (Q99J95) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 55.5 bits (132), Expect = 6e-08 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG VF+AK +TG+ VA+KKVL + + RE+++++ + H NVV+L Sbjct: 25 IGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 218 FFSTTS---RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + S R + + LV ++ L +L SN + L +K M L GL Y+H Sbjct: 85 CRTKASPYNRCKGSIYLVFDFCEHDLAGLL---SNVLVKFTLSEIKRVMQMLLNGLYYIH 141
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 55.5 bits (132), Expect = 6e-08 Identities = 36/119 (30%), Positives = 66/119 (55%), Gaps = 7/119 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ T ET+A+KK+ ++ + RE+ L++ M H N+V L+ Sbjct: 7 IGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQDV 66 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRM-PLIYVKLYMYQLFRGLAYVHT 391 S + L LV EY+ L KH ++ + + VK+++YQ+ G+AY H+ Sbjct: 67 VHS-----DKRLYLVFEYLDLDL---KKHMDSSPEFIKDPRQVKMFLYQMLCGIAYCHS 117
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 55.5 bits (132), Expect = 6e-08 Identities = 36/126 (28%), Positives = 65/126 (51%), Gaps = 14/126 (11%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKH 214 ++G G++G V++A+ +TGE VA+KKV D + RE++++R + H +++++K Sbjct: 710 IIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKE 769 Query: 215 CFFSTT-----SRDELFLNLVMEYVPETLYRVLKH---YSNANQRMPLIYVKLYMYQLFR 370 +D+ LV EY+ L +L+ + N N ++K +M QL Sbjct: 770 IVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNEN------HIKSFMRQLME 823 Query: 371 GLAYVH 388 GL Y H Sbjct: 824 GLDYCH 829
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 55.1 bits (131), Expect = 8e-08 Identities = 31/118 (26%), Positives = 62/118 (52%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++ + TG+ VA+KK+ + + RE+ L++ + HPN+V L+ Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHPNIVCLQDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 + L L+ E++ L + L + Q + VK Y+YQ+ +G+ + H+ Sbjct: 70 LM-----QDARLYLIFEFLSMDLKKYLDTIP-SGQYLDRSRVKSYLYQILQGIVFCHS 121
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 55.1 bits (131), Expect = 8e-08 Identities = 43/138 (31%), Positives = 68/138 (49%), Gaps = 12/138 (8%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQD--------RRYKNRELQLMRSMDH 190 +Y + VG G++G V +A T VAIKK+ + R Y REL+L++ MDH Sbjct: 23 TYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTY--RELRLLKHMDH 80 Query: 191 PNVVSLKHCFFSTTSRDEL----FLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMY 358 NV+ L F D L + +V + L +++ Q++ +V+ +Y Sbjct: 81 ENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIR-----TQKLSDDHVQFLVY 135 Query: 359 QLFRGLAYVHTVPGVCHR 412 Q+ RGL Y+H+ GV HR Sbjct: 136 QILRGLKYIHSA-GVIHR 152
>CDK9_BOVIN (Q5EAB2) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 55.1 bits (131), Expect = 8e-08 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG VF+AK +TG+ VA+KKVL + + RE+++++ + H NVV+L Sbjct: 25 IGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 218 FFSTTS---RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + S R + + LV ++ L +L SN + L +K M L GL Y+H Sbjct: 85 CRTKASPYNRCKGSIYLVFDFCEHDLAGLL---SNVLVKFTLSEIKRVMQMLLNGLYYIH 141
>MK14A_CYPCA (Q90336) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (cp38a) Length = 361 Score = 55.1 bits (131), Expect = 8e-08 Identities = 43/136 (31%), Positives = 69/136 (50%), Gaps = 9/136 (6%) Frame = +2 Query: 32 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQD--------RRYKNRELQLMRSMD 187 + Y VG+G++G V A +TG VA+KK+ + R Y REL+L++ M Sbjct: 23 VRYQNLSPVGSGAYGTVCSAYDEKTGLKVAVKKLSRPFQSIIHAKRTY--RELRLLKHMK 80 Query: 188 HPNVVSLKHCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQL 364 H NV+ L F TS +E + LV + L ++K Q++ +V+ +YQ+ Sbjct: 81 HENVIGLLDVFTPATSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQI 135 Query: 365 FRGLAYVHTVPGVCHR 412 RGL Y+H+ + HR Sbjct: 136 LRGLKYIHSA-DIIHR 150
>MK11_MOUSE (Q9WUI1) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B) Length = 364 Score = 55.1 bits (131), Expect = 8e-08 Identities = 40/128 (31%), Positives = 67/128 (52%), Gaps = 7/128 (5%) Frame = +2 Query: 50 RVVGTGSFGIVFQAKCLETGETVAIKKV------LQDRRYKNRELQLMRSMDHPNVVSLK 211 R VG+G++G V A + VA+KK+ L R REL+L++ + H NV+ L Sbjct: 28 RPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLL 87 Query: 212 HCFFSTTSRDELF-LNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F TS ++ + LV + L ++K + +++ +V+ +YQL RGL Y+H Sbjct: 88 DVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDE-----HVQFLVYQLLRGLKYIH 142 Query: 389 TVPGVCHR 412 + G+ HR Sbjct: 143 SA-GIIHR 149
>SSK2_YEAST (P53599) MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of| sensor kinase 2) Length = 1579 Score = 54.7 bits (130), Expect = 1e-07 Identities = 38/136 (27%), Positives = 67/136 (49%), Gaps = 8/136 (5%) Frame = +2 Query: 29 TISYMAERVVGTGSFGIVFQAKCLETGETVAIKKV-LQDRRYKNR-------ELQLMRSM 184 ++ + +G G+FG V+ A L+ GE +A+K++ +QD + + E+ ++ + Sbjct: 1263 SMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEIL 1322 Query: 185 DHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQL 364 +HPN+VS + RD+ +N+ MEY L + M ++Y QL Sbjct: 1323 NHPNIVSY---YGVEVHRDK--VNIFMEYCEGGSLAALLEHGRIEDEM---VTQVYTLQL 1374 Query: 365 FRGLAYVHTVPGVCHR 412 GLAY+H G+ HR Sbjct: 1375 LEGLAYLHE-SGIVHR 1389
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 54.7 bits (130), Expect = 1e-07 Identities = 37/124 (29%), Positives = 63/124 (50%), Gaps = 5/124 (4%) Frame = +2 Query: 32 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPN 196 ++Y +G G++ V++ + TGE VA+K + D RE+ LM+ + HPN Sbjct: 1 MNYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPN 60 Query: 197 VVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 ++SL S + E L LV EY+ + L + + Y N +P VK + QL +G+ Sbjct: 61 IMSL-----SDVLQTENKLMLVFEYMEKDLKKYMDTYGNQG-ALPPSQVKNFTQQLLKGI 114 Query: 377 AYVH 388 ++ H Sbjct: 115 SFCH 118
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 54.7 bits (130), Expect = 1e-07 Identities = 39/126 (30%), Positives = 62/126 (49%), Gaps = 7/126 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDH-PNVVSLKH 214 VG G++G V++A TG+ VA+KK + RE+ L+R + P+VV L Sbjct: 20 VGEGTYGKVYRAMEKSTGKIVALKKTRLHEDEEGVPPTTLREVSLLRMLSRDPHVVRLLD 79 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 + L LV EY+ L + ++ + + + + VK MYQL +G+A+ H Sbjct: 80 VKQGQNKEGKTVLYLVFEYMDTDLKKYIRSFKQTGESIAPMNVKSLMYQLCKGVAFCHG- 138 Query: 395 PGVCHR 412 GV HR Sbjct: 139 HGVLHR 144
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 54.7 bits (130), Expect = 1e-07 Identities = 34/117 (29%), Positives = 62/117 (52%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKHC 217 +G GS+G+VF+ + +G+ VAIKK ++ R+ RE+++++ + HPN+V+L Sbjct: 10 IGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQLKHPNLVNLIEV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F R + ++LV EY TL L+ N + +K ++Q + L + H Sbjct: 70 F-----RRKRKMHLVFEYCDHTLLNELERNPNG---VSDGVIKSVLWQTLQALNFCH 118
>MK15_RAT (Q9Z2A6) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 547 Score = 54.3 bits (129), Expect = 1e-07 Identities = 38/125 (30%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSM-DHPN 196 Y+ +R +G G++GIV++A TGE VAIKK+ D + RE+ L+R HPN Sbjct: 14 YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIMLLREFGGHPN 73 Query: 197 VVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 ++ L + RD + LV E + L V++ + + I+ + YQL R Sbjct: 74 IIRLLDVIPAKNDRD---IYLVFESMDTDLNAVIQ----KGRLLEDIHKRCIFYQLLRAT 126 Query: 377 AYVHT 391 ++H+ Sbjct: 127 KFIHS 131
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 54.3 bits (129), Expect = 1e-07 Identities = 38/134 (28%), Positives = 64/134 (47%), Gaps = 6/134 (4%) Frame = +2 Query: 29 TISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDH 190 T Y + +G G++G+V++A+ T TVA+K++ D + RE+ L++ + H Sbjct: 2 TSRYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRH 61 Query: 191 PNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFR 370 N+V L S E L +V EY+ L K+ N + ++ +M L R Sbjct: 62 ENIVKLLDVCHS-----EHRLTIVFEYLDLDL---KKYLDRENGNLDAATIQHFMRDLLR 113 Query: 371 GLAYVHTVPGVCHR 412 G+A+ H V HR Sbjct: 114 GVAFCHQ-RSVLHR 126
>MK04_RAT (Q63454) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) (MNK2) (Fragment) Length = 274 Score = 54.3 bits (129), Expect = 1e-07 Identities = 44/136 (32%), Positives = 66/136 (48%), Gaps = 10/136 (7%) Frame = +2 Query: 59 GTGSFGIVFQAKCLETGETVAIKK-VLQDRR---YKNRELQLMRSMDHPNVVSLKHCFFS 226 G G G+V A VA+KK VL D R + RE++++R +DH N+V + Sbjct: 1 GCGGNGLVLSATDSRACRKVAVKKIVLSDARSMKHALREIKIIRRLDHDNIVKVYEVLGP 60 Query: 227 TTS--RDELF----LNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 S + ELF +V EY+ L +L+ + + + KL+MYQL RGL Y+H Sbjct: 61 KGSDLQGELFKFSVAYIVQEYMETDLACLLEQGTLTEE-----HAKLFMYQLLRGLKYIH 115 Query: 389 TVPGVCHRGCETTKCF 436 + V HR + F Sbjct: 116 SA-NVLHRDLKPANIF 130
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 54.3 bits (129), Expect = 1e-07 Identities = 34/116 (29%), Positives = 58/116 (50%), Gaps = 5/116 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNVVSLKHCF 220 +G G++ V++ + TG+ VA+K++ D RE+ LM+ + H N+V+L Sbjct: 13 LGEGTYATVYKGRNRTTGQLVALKEINLDSEEGTPSTAIREISLMKELKHENIVTLYDVI 72 Query: 221 FSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + LNLV EY+ + L + + N + VK +MYQL RG+ + H Sbjct: 73 HTENK-----LNLVFEYMDKDLKKFMDTNGNKGA-LETKQVKWFMYQLLRGILFCH 122
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 54.3 bits (129), Expect = 1e-07 Identities = 38/125 (30%), Positives = 63/125 (50%), Gaps = 6/125 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G VF+ + +T E VA+K+V D + RE+ L++ + H N+V L Sbjct: 10 IGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLIDV 69 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 S L LV E+ + L K++ + N + + + +M QL RGLA+ H+ Sbjct: 70 LHSDKK-----LTLVFEHCDQDL---KKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHS-H 120 Query: 398 GVCHR 412 V HR Sbjct: 121 NVLHR 125
>CDK9B_XENLA (Q7ZX42) Cell division protein kinase 9-B (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-B) Length = 376 Score = 54.3 bits (129), Expect = 1e-07 Identities = 39/124 (31%), Positives = 64/124 (51%), Gaps = 13/124 (10%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG VF+AK +TG+ VA+KKVL + + RE+++++ + H NVV L Sbjct: 25 IGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVHLIEI 84 Query: 218 FFSTTS-------RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 + S R + + LV ++ L +L SNA+ + + +K M L GL Sbjct: 85 CRNKISPTANQYNRCKGTIFLVFDFCEHDLAGLL---SNAHVKFTVAEIKKVMQMLLNGL 141 Query: 377 AYVH 388 Y+H Sbjct: 142 YYIH 145
>CDK9_HUMAN (P50750) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4) Length = 372 Score = 53.9 bits (128), Expect = 2e-07 Identities = 38/120 (31%), Positives = 63/120 (52%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG VF+A+ +TG+ VA+KKVL + + RE+++++ + H NVV+L Sbjct: 25 IGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 218 FFSTTS---RDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + S R + + LV ++ L +L SN + L +K M L GL Y+H Sbjct: 85 CRTKASPYNRCKGSIYLVFDFCEHDLAGLL---SNVLVKFTLSEIKRVMQMLLNGLYYIH 141
>MK14A_BRARE (Q9DGE2) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (zp38a) Length = 361 Score = 53.9 bits (128), Expect = 2e-07 Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 9/136 (6%) Frame = +2 Query: 32 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQD--------RRYKNRELQLMRSMD 187 + Y VG+G++G V A +TG VA+KK+ + R Y REL+L++ M Sbjct: 23 VQYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTY--RELRLLKHMR 80 Query: 188 HPNVVSLKHCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQL 364 H NV+ L F TS E + LV + L ++K Q++ +V+ +YQ+ Sbjct: 81 HENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQI 135 Query: 365 FRGLAYVHTVPGVCHR 412 RGL Y+H+ + HR Sbjct: 136 LRGLKYIHSA-DIIHR 150
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 53.9 bits (128), Expect = 2e-07 Identities = 34/117 (29%), Positives = 62/117 (52%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ GE A+KK+ + + RE+ L++ + HPN+V L+ Sbjct: 10 IGEGTYGVVYKAQN-NHGEICALKKIRVEEEDEGIPSTAIREISLLKELHHPNIVWLRDV 68 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 S E L LV EY+ + L ++L + + K ++YQ+ RG++Y H Sbjct: 69 IHS-----EKCLTLVFEYLDQDLKKLL---DACDGGLEPTTAKSFLYQILRGISYCH 117
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 53.9 bits (128), Expect = 2e-07 Identities = 34/117 (29%), Positives = 62/117 (52%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++A+ GE A+KK+ + + RE+ L++ + HPN+V L+ Sbjct: 10 IGEGTYGVVYKAQN-NHGEICALKKIRVEEEDEGIPSTAIREISLLKELHHPNIVWLRDV 68 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 S E L LV EY+ + L ++L + + K ++YQ+ RG++Y H Sbjct: 69 IHS-----EKCLTLVFEYLDQDLKKLL---DACDGGLEPTTAKSFLYQILRGISYCH 117
>NEK6_RAT (P59895) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 53.9 bits (128), Expect = 2e-07 Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 8/141 (5%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKV----LQDRRYKN---RELQLMRSMDHPN 196 + E+ +G G F V++A CL +TVA+KKV + D + + +E+ L++ ++HPN Sbjct: 45 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN 104 Query: 197 VVSLKHCFFSTTSRDELFLNLVMEYVPE-TLYRVLKHYSNANQRMPLIYVKLYMYQLFRG 373 ++ F LN+V+E L +++K++ + +P V Y QL Sbjct: 105 IIKYLDSFIEDNE-----LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSA 159 Query: 374 LAYVHTVPGVCHRGCETTKCF 436 + ++H+ V HR + F Sbjct: 160 VEHMHS-RRVMHRDIKPANVF 179
>NEK6_MOUSE (Q9ES70) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 53.9 bits (128), Expect = 2e-07 Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 8/141 (5%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKV----LQDRRYKN---RELQLMRSMDHPN 196 + E+ +G G F V++A CL +TVA+KKV + D + + +E+ L++ ++HPN Sbjct: 45 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN 104 Query: 197 VVSLKHCFFSTTSRDELFLNLVMEYVPE-TLYRVLKHYSNANQRMPLIYVKLYMYQLFRG 373 ++ F LN+V+E L +++K++ + +P V Y QL Sbjct: 105 IIKYLDSFIEDNE-----LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSA 159 Query: 374 LAYVHTVPGVCHRGCETTKCF 436 + ++H+ V HR + F Sbjct: 160 VEHMHS-RRVMHRDIKPANVF 179
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 53.9 bits (128), Expect = 2e-07 Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 8/141 (5%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKV----LQDRRYKN---RELQLMRSMDHPN 196 + E+ +G G F V++A CL +TVA+KKV + D + + +E+ L++ ++HPN Sbjct: 45 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPN 104 Query: 197 VVSLKHCFFSTTSRDELFLNLVMEYVPE-TLYRVLKHYSNANQRMPLIYVKLYMYQLFRG 373 ++ F LN+V+E L +++K++ + +P V Y QL Sbjct: 105 IIKYLDSFIEDNE-----LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSA 159 Query: 374 LAYVHTVPGVCHRGCETTKCF 436 + ++H+ V HR + F Sbjct: 160 VEHMHS-RRVMHRDIKPANVF 179
>JNK1_CAEEL (Q8WQG9) Stress-activated protein kinase jnk-1 (EC 2.7.11.24)| Length = 463 Score = 53.9 bits (128), Expect = 2e-07 Identities = 43/136 (31%), Positives = 71/136 (52%), Gaps = 11/136 (8%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN--------RELQLMRSMDHP 193 Y R++G+G+ GIV A E VAIKK+ R ++N REL+LM ++H Sbjct: 119 YQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKL--SRPFQNVTHAKRAYRELKLMSLVNHK 176 Query: 194 NVVSLKHCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKL--YMYQL 364 N++ + +CF DE L +VME + L +V+ +M L + +L +YQ+ Sbjct: 177 NIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVI--------QMDLDHERLSYLLYQM 228 Query: 365 FRGLAYVHTVPGVCHR 412 G+ ++H+ G+ HR Sbjct: 229 LCGIRHLHSA-GIIHR 243
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 53.5 bits (127), Expect = 2e-07 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 11/107 (10%) Frame = +2 Query: 11 NGEPKRTIS---YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-------- 157 +G+P+ ++ Y+ R +G GSFG+V QA+ L T E VAIK +L+ N Sbjct: 35 SGQPESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLY 94 Query: 158 RELQLMRSMDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVL 298 EL +++ + HPN+VS K F S+D+ ++ + E R+L Sbjct: 95 EELSILQKLSHPNIVSFKDWF---ESKDKFYIVTQLATGGELFDRIL 138
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 53.5 bits (127), Expect = 2e-07 Identities = 40/143 (27%), Positives = 74/143 (51%), Gaps = 15/143 (10%) Frame = +2 Query: 29 TISYMAERVVGTGSFGIVFQAKCLETGETVAIKKV--------LQDRRYK------NREL 166 T +M ++G G++G VF A + TGE +A+K+V D+ K N E+ Sbjct: 822 TFKWMKGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEI 881 Query: 167 QLMRSMDHPNVVSLKHCFFSTTSRDELFLNLVMEYVP-ETLYRVLKHYSNANQRMPLIYV 343 ++ +DH N+V ++ F T D +++ +EYV ++ R L++Y +++ V Sbjct: 882 SMIADLDHLNIV--QYLGFEKTETD---ISIFLEYVSGGSIGRCLRNYGPFEEQL----V 932 Query: 344 KLYMYQLFRGLAYVHTVPGVCHR 412 + Q+ GL+Y+H+ G+ HR Sbjct: 933 RFVSRQVLYGLSYLHS-KGIIHR 954
>MK14_MOUSE (P47811) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 53.5 bits (127), Expect = 2e-07 Identities = 46/146 (31%), Positives = 73/146 (50%), Gaps = 14/146 (9%) Frame = +2 Query: 17 EPKRTISYMAERV-----VGTGSFGIVFQAKCLETGETVAIKKVLQD--------RRYKN 157 E +TI + ER VG+G++G V A +TG VA+KK+ + R Y Sbjct: 11 ELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTY-- 68 Query: 158 RELQLMRSMDHPNVVSLKHCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPL 334 REL+L++ M H NV+ L F S +E + LV + L ++K Q++ Sbjct: 69 RELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTD 123 Query: 335 IYVKLYMYQLFRGLAYVHTVPGVCHR 412 +V+ +YQ+ RGL Y+H+ + HR Sbjct: 124 DHVQFLIYQILRGLKYIHSA-DIIHR 148
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 53.5 bits (127), Expect = 2e-07 Identities = 35/123 (28%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNV 199 +Y+ +G G++ V++ + T VA+K++ + RE+ L++ + H N+ Sbjct: 191 TYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANI 250 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+L + S L LV EY+ + L + + N M + VKL++YQ+ RGLA Sbjct: 251 VTLHDIVHTDKS-----LTLVFEYLDKDLKQYMDDCGNI---MSMHNVKLFLYQILRGLA 302 Query: 380 YVH 388 Y H Sbjct: 303 YCH 305
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 53.5 bits (127), Expect = 2e-07 Identities = 35/123 (28%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNV 199 +Y+ +G G++ V++ + T VA+K++ + RE+ L++ + H N+ Sbjct: 191 TYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANI 250 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+L + S L LV EY+ + L + + N M + VKL++YQ+ RGLA Sbjct: 251 VTLHDIVHTDKS-----LTLVFEYLDKDLKQYMDDCGNI---MSMHNVKLFLYQILRGLA 302 Query: 380 YVH 388 Y H Sbjct: 303 YCH 305
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 53.1 bits (126), Expect = 3e-07 Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 6/118 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++GIV++A+ TG+ VA+KK+ + + RE+ L++++ HPNVV L Sbjct: 14 IGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDV 73 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHT 391 S + L ++ EY+ L +++ + +K YM+Q+ + + HT Sbjct: 74 VISGNN-----LYMIFEYLNMDLKKLMDKKKDVFTPQ---LIKSYMHQILDAVGFCHT 123
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 53.1 bits (126), Expect = 3e-07 Identities = 35/126 (27%), Positives = 66/126 (52%), Gaps = 6/126 (4%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKH 214 +VG GS+G+V + + ++G VAIKK L+ ++ RE++L++ + H N+V+L Sbjct: 9 LVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLE 68 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 + + LV E+V T+ LK + N + V+ Y++Q+ G+ + H+ Sbjct: 69 -----VCKKKKRWYLVFEFVDHTILDDLKLFPNG---LDYQVVQKYLFQIINGIGFCHS- 119 Query: 395 PGVCHR 412 + HR Sbjct: 120 HNIIHR 125
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 53.1 bits (126), Expect = 3e-07 Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 5/116 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNVVSLKHCF 220 +G G++ V++ + TG VA+K++ D RE+ LM+ +DH N+V+L Sbjct: 14 LGEGTYATVYKGRNRATGALVALKEISLDSEEGTPSTAIREISLMKELDHENIVTLYDVI 73 Query: 221 FSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + E L LV EY+ + L + ++ + + L VK +M+QL +G+ + H Sbjct: 74 HT-----ENKLTLVFEYMDKDLKKYMEVHGQ-QSALDLKVVKSFMFQLLKGIMFCH 123
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 53.1 bits (126), Expect = 3e-07 Identities = 35/126 (27%), Positives = 66/126 (52%), Gaps = 6/126 (4%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKH 214 +VG GS+G+V + + ++G VAIKK L+ ++ RE++L++ + H N+V+L Sbjct: 9 LVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLE 68 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 + + LV E+V T+ LK + N + V+ Y++Q+ G+ + H+ Sbjct: 69 -----VCKKKKRWYLVFEFVDHTILDDLKLFPNG---LDYQVVQKYLFQIINGIGFCHS- 119 Query: 395 PGVCHR 412 + HR Sbjct: 120 HNIIHR 125
>MHK_ARATH (P43294) Serine/threonine-protein kinase MHK (EC 2.7.11.22)| Length = 443 Score = 53.1 bits (126), Expect = 3e-07 Identities = 37/124 (29%), Positives = 64/124 (51%), Gaps = 5/124 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRY-----KNRELQLMRSMDHPNVVSLKHCF 220 +G G+ G V++A LET E VA+KK+ + Y RE++ +R ++HP+++ LK Sbjct: 18 LGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKALRKLNHPHIIKLKEI- 76 Query: 221 FSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVPG 400 +ELF + E + LY ++K ++ +M Q+ +GLA++H G Sbjct: 77 --VREHNELF--FIFECMDHNLYHIMKERERPFSEGE---IRSFMSQMLQGLAHMHK-NG 128 Query: 401 VCHR 412 HR Sbjct: 129 YFHR 132
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 53.1 bits (126), Expect = 3e-07 Identities = 35/126 (27%), Positives = 66/126 (52%), Gaps = 6/126 (4%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKH 214 +VG GS+G+V + + +TG VAIKK L+ ++ RE++L++ + H N+V+L Sbjct: 9 LVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLE 68 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 + + LV E+V T+ L+ + N + V+ Y++Q+ G+ + H+ Sbjct: 69 -----VCKKKKRWYLVFEFVDHTILDDLELFPNG---LDYQVVQKYLFQIINGIGFCHS- 119 Query: 395 PGVCHR 412 + HR Sbjct: 120 HNIIHR 125
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 53.1 bits (126), Expect = 3e-07 Identities = 35/126 (27%), Positives = 66/126 (52%), Gaps = 6/126 (4%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKH 214 +VG GS+G+V + + +TG VAIKK L+ ++ RE++L++ + H N+V+L Sbjct: 9 LVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLE 68 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 + + LV E+V T+ L+ + N + V+ Y++Q+ G+ + H+ Sbjct: 69 -----VCKKKKRWYLVFEFVDHTILDDLELFPNG---LDYQVVQKYLFQIINGIGFCHS- 119 Query: 395 PGVCHR 412 + HR Sbjct: 120 HNIIHR 125
>MK14_RAT (P70618) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 53.1 bits (126), Expect = 3e-07 Identities = 41/128 (32%), Positives = 66/128 (51%), Gaps = 9/128 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQD--------RRYKNRELQLMRSMDHPNVVSLK 211 VG+G++G V A +TG VA+KK+ + R Y REL+L++ M H NV+ L Sbjct: 29 VGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTY--RELRLLKHMKHENVIGLL 86 Query: 212 HCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F S +E + LV + L ++K Q++ +V+ +YQ+ RGL Y+H Sbjct: 87 DVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRGLKYIH 141 Query: 389 TVPGVCHR 412 + + HR Sbjct: 142 SA-DIIHR 148
>MK15_MOUSE (Q80Y86) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 549 Score = 53.1 bits (126), Expect = 3e-07 Identities = 37/125 (29%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSM-DHPN 196 Y+ +R +G G++GIV++A TGE VAIKK+ D + RE+ L++ HPN Sbjct: 14 YLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHPN 73 Query: 197 VVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGL 376 ++ L + RD + LV E + L V++ + + I+ + YQL R Sbjct: 74 IIRLLDVIPAKNDRD---IYLVFESMDTDLNAVIQ----KGRLLKDIHKRCIFYQLLRAT 126 Query: 377 AYVHT 391 ++H+ Sbjct: 127 KFIHS 131
>MK03_HUMAN (P27361) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) Length = 379 Score = 53.1 bits (126), Expect = 3e-07 Identities = 42/164 (25%), Positives = 75/164 (45%), Gaps = 27/164 (16%) Frame = +2 Query: 2 GGKNGEPKRTIS----------------------YMAERVVGTGSFGIVFQAKCLETGET 115 GG GEP+RT Y + +G G++G+V A Sbjct: 8 GGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTR 67 Query: 116 VAIKKV--LQDRRYKNR---ELQLMRSMDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPE 280 VAIKK+ + + Y R E+Q++ H NV+ ++ ++T + +V + + Sbjct: 68 VAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMET 127 Query: 281 TLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVPGVCHR 412 LY++LK +Q++ ++ ++YQ+ RGL Y+H+ V HR Sbjct: 128 DLYKLLK-----SQQLSNDHICYFLYQILRGLKYIHSA-NVLHR 165
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 53.1 bits (126), Expect = 3e-07 Identities = 36/123 (29%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNV 199 +Y+ +G G++ V++ K T VA+K++ + RE+ L++ + H N+ Sbjct: 164 TYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANI 223 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+L + S L LV EY+ + L + L N + + VKL+++QL RGLA Sbjct: 224 VTLHDIIHTEKS-----LTLVFEYLDKDLKQYLDDCGNV---INMHNVKLFLFQLLRGLA 275 Query: 380 YVH 388 Y H Sbjct: 276 YCH 278
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 53.1 bits (126), Expect = 3e-07 Identities = 36/123 (29%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNV 199 +Y+ +G G++ V++ K T VA+K++ + RE+ L++ + H N+ Sbjct: 164 TYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANI 223 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+L + S L LV EY+ + L + L N + + VKL+++QL RGLA Sbjct: 224 VTLHDIIHTEKS-----LTLVFEYLDKDLKQYLDDCGNV---INMHNVKLFLFQLLRGLA 275 Query: 380 YVH 388 Y H Sbjct: 276 YCH 278
>BUR1_EMENI (Q96VK3) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) (Pitalre-like kinase A) Length = 544 Score = 53.1 bits (126), Expect = 3e-07 Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 13/124 (10%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG V++A+ G VA+KK+L RE++L++ + H N++ L+ Sbjct: 31 LGEGTFGEVYKARAKRDGSIVALKKILMHNERDGFPITALREIKLLKMLSHTNIMQLREM 90 Query: 218 FFSTT---SRDELFLNLVMEYVPETLYRVLK----HYSNANQRMPLIYVKLYMYQLFRGL 376 + R + + +V Y+ L +L+ H+S A +K YM QL GL Sbjct: 91 AVERSKGEGRKKPSMYMVFPYMEHDLSGLLENPEVHFSEAQ-------IKCYMIQLLEGL 143 Query: 377 AYVH 388 Y+H Sbjct: 144 KYLH 147
>BUR1_NEUCR (Q871M9) Serine/threonine-protein kinase bur-1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 545 Score = 52.8 bits (125), Expect = 4e-07 Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 10/131 (7%) Frame = +2 Query: 26 RTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMD 187 R Y +G G+FG V +A+ +TG VA+KK++ RE++L++ + Sbjct: 22 RIADYEVLGKLGEGTFGEVHRARSRKTGALVALKKIIMHNERDGFPITALREIKLLKLLS 81 Query: 188 HPNVVSLKHCFFS----TTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYM 355 H NV+ L+ T R + +V Y+ L +L N + R VK Y+ Sbjct: 82 HKNVLRLEEMAIEHPPRTDKRTRPIVYMVTPYMDHDLSGLL---DNPSVRFTEPQVKCYL 138 Query: 356 YQLFRGLAYVH 388 QL GL Y+H Sbjct: 139 LQLLEGLKYLH 149
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 52.8 bits (125), Expect = 4e-07 Identities = 38/129 (29%), Positives = 67/129 (51%), Gaps = 7/129 (5%) Frame = +2 Query: 47 ERVVGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRSM-DHPNVVS 205 ++ +G G++GIV++A + ETVA+KK+ D + RE+ ++ HPNV+ Sbjct: 16 QKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIK 75 Query: 206 LKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYV 385 L + F + RD + L E++ L+ V+K S ++ + M QLFR + ++ Sbjct: 76 LYNIFRADNDRD---IYLAFEFMEADLHNVIKKGSILKD----VHKQYIMCQLFRAIRFL 128 Query: 386 HTVPGVCHR 412 H+ V HR Sbjct: 129 HS-GNVLHR 136
>MK04_MOUSE (Q6P5G0) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) Length = 583 Score = 52.8 bits (125), Expect = 4e-07 Identities = 44/137 (32%), Positives = 66/137 (48%), Gaps = 10/137 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKK-VLQDRR---YKNRELQLMRSMDHPNVVSLKHCFF 223 +G G G+V A VA+KK VL D R + RE++++R +DH N+V + Sbjct: 26 LGFGVNGLVLSATDSRACRKVAVKKIVLSDARSMKHALREIKIIRRLDHDNIVKVYEVLG 85 Query: 224 STTS--RDELF----LNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYV 385 S + ELF +V EY+ L +L+ + + KL+MYQL RGL Y+ Sbjct: 86 PKGSDLQGELFKFSVAYIVQEYMETDLACLLEQGTLTED-----HAKLFMYQLLRGLKYI 140 Query: 386 HTVPGVCHRGCETTKCF 436 H+ V HR + F Sbjct: 141 HSA-NVLHRDLKPANIF 156
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 52.8 bits (125), Expect = 4e-07 Identities = 35/126 (27%), Positives = 66/126 (52%), Gaps = 6/126 (4%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKH 214 +VG GS+G+V + + +TG VAIKK L+ ++ RE++L++ + H N+V+L Sbjct: 9 LVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLE 68 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 + + LV E+V T+ L+ + N + V+ Y++Q+ G+ + H+ Sbjct: 69 -----VCKKKKRWYLVFEFVDHTILDDLELFPNG---LDYQVVQKYLFQIINGIGFCHS- 119 Query: 395 PGVCHR 412 + HR Sbjct: 120 HNIIHR 125
>CDK8_HUMAN (P49336) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (Protein kinase K35) Length = 464 Score = 52.8 bits (125), Expect = 4e-07 Identities = 37/120 (30%), Positives = 66/120 (55%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLE--TGETVAIKKVLQDRRYKN--RELQLMRSMDHPNVVSLKHCFF 223 VG G++G V++AK + + A+K++ + RE+ L+R + HPNV+SL+ F Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFL 86 Query: 224 STTSRDELFLNLVMEYVPETLYRVLKHY--SNANQR---MPLIYVKLYMYQLFRGLAYVH 388 S R + L+ +Y L+ ++K + S AN++ +P VK +YQ+ G+ Y+H Sbjct: 87 SHADRK---VWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLH 143
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 52.8 bits (125), Expect = 4e-07 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 7/126 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDR------RYKNRELQLMRSM-DHPNVVSLKH 214 +G G+ GIVF+AK +ETGE VA+KKV R RE++ ++ M D+ VV LK Sbjct: 10 IGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEMEDNQYVVQLKA 69 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 F + L E++ L V++H A + + VK Y+ L +G+++ H Sbjct: 70 VFPHSAG-----FVLAFEFMLSDLAEVVRH---AQRPLAQAQVKSYLQMLLKGVSFCH-A 120 Query: 395 PGVCHR 412 + HR Sbjct: 121 NNIVHR 126
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/123 (29%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNV 199 +Y+ +G G++ V++ K T VA+K++ + RE+ L++ + H N+ Sbjct: 164 TYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANI 223 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+L + S L LV EY+ + L + L N + + VKL+++QL RGLA Sbjct: 224 VTLHDIIHTEKS-----LTLVFEYLDKDLKQYLDDCGNI---INMHNVKLFLFQLLRGLA 275 Query: 380 YVH 388 Y H Sbjct: 276 YCH 278
>ERKA_DROME (P40417) Mitogen-activated protein kinase ERK-A (EC 2.7.11.24)| (Extracellular-regulated kinase A) (Protein rolled) Length = 376 Score = 52.8 bits (125), Expect = 4e-07 Identities = 37/131 (28%), Positives = 69/131 (52%), Gaps = 6/131 (4%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKV--LQDRRYKNR---ELQLMRSMDHPNVV 202 Y+ +G G++G+V A T + VAIKK+ + + Y R E+ ++ H N++ Sbjct: 38 YIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQRTLREITILTRFKHENII 97 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPET-LYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 ++ S D++ +++ + ET LY++LK QR+ ++ ++YQ+ RGL Sbjct: 98 DIRD-ILRVDSIDQMRDVYIVQCLMETDLYKLLK-----TQRLSNDHICYFLYQILRGLK 151 Query: 380 YVHTVPGVCHR 412 Y+H+ V HR Sbjct: 152 YIHSA-NVLHR 161
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 52.8 bits (125), Expect = 4e-07 Identities = 37/133 (27%), Positives = 66/133 (49%), Gaps = 8/133 (6%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNR--------ELQLMRSMDHP 193 Y+ + +G G+FG+V QAK ETGE VA+K +++ N+ EL +++ + HP Sbjct: 37 YVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHP 96 Query: 194 NVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRG 373 N+V+ K F S+D+ ++ + E R+LK + I V ++ Sbjct: 97 NIVAFKDWF---ESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILV-----EILSA 148 Query: 374 LAYVHTVPGVCHR 412 + Y+H+ + HR Sbjct: 149 VKYMHS-QNIVHR 160
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 52.4 bits (124), Expect = 5e-07 Identities = 37/129 (28%), Positives = 64/129 (49%), Gaps = 7/129 (5%) Frame = +2 Query: 23 KRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-------RELQLMRS 181 K + Y E+ VG G++ +V+ TG +AIK++ + +K+ RE++ ++ Sbjct: 2 KVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEI-KTSEFKDGLDMSAIREVKYLQE 60 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 M HPNV+ L F + + LNLV+E++P L V+K S +K +M Sbjct: 61 MQHPNVIELIDIFMAYDN-----LNLVLEFLPTDLEVVIKDKSIL---FTPADIKAWMLM 112 Query: 362 LFRGLAYVH 388 RG+ + H Sbjct: 113 TLRGVYHCH 121
>CD2L7_CAEEL (P46551) Putative cell division cycle 2-related protein kinase 7| (EC 2.7.11.22) Length = 730 Score = 52.4 bits (124), Expect = 5e-07 Identities = 43/132 (32%), Positives = 62/132 (46%), Gaps = 13/132 (9%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G V++A TGE VA+K+V + + RE++++R + H N+V L Sbjct: 317 IGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDI 376 Query: 218 FFSTTSRDEL-----FLNLVMEYVPETLYRVL--KHYSNANQRMPLIYVKLYMYQLFRGL 376 S DEL LV EYV L +L K + N+ K QL GL Sbjct: 377 VIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFK----QLLEGL 432 Query: 377 AYVHTVPGVCHR 412 AY+H G HR Sbjct: 433 AYIHNT-GFLHR 443
>MK14A_DROME (O62618) Mitogen-activated protein kinase 14A (EC 2.7.11.24) (MAP| kinase p38a) (p38 MAPK) (Dp38) (D-p38a) Length = 366 Score = 52.4 bits (124), Expect = 5e-07 Identities = 43/133 (32%), Positives = 64/133 (48%), Gaps = 8/133 (6%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQD--------RRYKNRELQLMRSMDHP 193 Y + VG+G++G V +A T VAIKK+ + R Y REL+L++ MDH Sbjct: 25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTY--RELRLLKHMDHE 82 Query: 194 NVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRG 373 NV+ L F + L N Y+ L + Q + +V+ +YQ+ RG Sbjct: 83 NVIGLLDIFHPHPANGSL-ENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRG 141 Query: 374 LAYVHTVPGVCHR 412 L Y+H+ GV HR Sbjct: 142 LKYIHSA-GVIHR 153
>MK01_XENLA (P26696) Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Myelin| xP42 protein kinase) (Myelin basic protein kinase) (MBP kinase) (M phase MAP kinase) Length = 361 Score = 52.4 bits (124), Expect = 5e-07 Identities = 33/124 (26%), Positives = 62/124 (50%), Gaps = 5/124 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKV--LQDRRYKNR---ELQLMRSMDHPNVVSLKHCF 220 +G G++G+V A C VAIKK+ + + Y R E++++ H N++ + Sbjct: 34 IGEGAYGMVCSAHCNINKVRVAIKKISPFEHQTYCQRTLREIKILLRFKHENIIGINDII 93 Query: 221 FSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVPG 400 + T + +V + + LY++LK +N ++ ++YQ+ RGL Y+H+ Sbjct: 94 RAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSND-----HICYFLYQILRGLKYIHSA-N 147 Query: 401 VCHR 412 V HR Sbjct: 148 VLHR 151
>MK14_PANTR (Q95NE7) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) Length = 359 Score = 52.4 bits (124), Expect = 5e-07 Identities = 46/146 (31%), Positives = 73/146 (50%), Gaps = 14/146 (9%) Frame = +2 Query: 17 EPKRTISYMAERV-----VGTGSFGIVFQAKCLETGETVAIKKVLQD--------RRYKN 157 E +TI + ER VG+G++G V A +TG VA+KK+ + R Y Sbjct: 11 ELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTY-- 68 Query: 158 RELQLMRSMDHPNVVSLKHCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPL 334 REL+L++ M H NV+ L F S +E + LV + L ++K Q++ Sbjct: 69 RELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTD 123 Query: 335 IYVKLYMYQLFRGLAYVHTVPGVCHR 412 +V+ +YQ+ RGL Y+H+ + HR Sbjct: 124 DHVQFLIYQILRGLKYIHSA-DIIHR 148
>MK14_HUMAN (Q16539) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting prote Length = 359 Score = 52.4 bits (124), Expect = 5e-07 Identities = 46/146 (31%), Positives = 73/146 (50%), Gaps = 14/146 (9%) Frame = +2 Query: 17 EPKRTISYMAERV-----VGTGSFGIVFQAKCLETGETVAIKKVLQD--------RRYKN 157 E +TI + ER VG+G++G V A +TG VA+KK+ + R Y Sbjct: 11 ELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTY-- 68 Query: 158 RELQLMRSMDHPNVVSLKHCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPL 334 REL+L++ M H NV+ L F S +E + LV + L ++K Q++ Sbjct: 69 RELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTD 123 Query: 335 IYVKLYMYQLFRGLAYVHTVPGVCHR 412 +V+ +YQ+ RGL Y+H+ + HR Sbjct: 124 DHVQFLIYQILRGLKYIHSA-DIIHR 148
>MK14_CANFA (O02812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) Length = 359 Score = 52.4 bits (124), Expect = 5e-07 Identities = 46/146 (31%), Positives = 73/146 (50%), Gaps = 14/146 (9%) Frame = +2 Query: 17 EPKRTISYMAERV-----VGTGSFGIVFQAKCLETGETVAIKKVLQD--------RRYKN 157 E +TI + ER VG+G++G V A +TG VA+KK+ + R Y Sbjct: 11 ELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTY-- 68 Query: 158 RELQLMRSMDHPNVVSLKHCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPL 334 REL+L++ M H NV+ L F S +E + LV + L ++K Q++ Sbjct: 69 RELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK-----CQKLTD 123 Query: 335 IYVKLYMYQLFRGLAYVHTVPGVCHR 412 +V+ +YQ+ RGL Y+H+ + HR Sbjct: 124 DHVQFLIYQILRGLKYIHSA-DIIHR 148
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 52.4 bits (124), Expect = 5e-07 Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNV 199 +Y+ +G G++ V++ + T VA+K++ + RE+ L++ + H N+ Sbjct: 191 TYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANI 250 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V+L + S L LV EY+ + L + + + M + VKL++YQ+ RGLA Sbjct: 251 VTLHDIVHTDKS-----LTLVFEYLDKDLKQYM---DDCGSIMSMHNVKLFLYQILRGLA 302 Query: 380 YVH 388 Y H Sbjct: 303 YCH 305
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 52.0 bits (123), Expect = 6e-07 Identities = 39/134 (29%), Positives = 70/134 (52%), Gaps = 4/134 (2%) Frame = +2 Query: 23 KRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYK----NRELQLMRSMDH 190 ++++ Y ++V+G GS+G+V++A T + VAIK+V+ + + E+ L+++++H Sbjct: 20 EKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNH 79 Query: 191 PNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFR 370 N+V H F R L +++EY R L S ++ + K Y+ Q Sbjct: 80 NNIVKY-HGFI----RKSYELYILLEYCANGSLRRL--ISRSSTGLSENESKTYVTQTLL 132 Query: 371 GLAYVHTVPGVCHR 412 GL Y+H GV HR Sbjct: 133 GLKYLHG-EGVIHR 145
>SKY1_YEAST (Q03656) Serine/threonine-protein kinase SKY1 (EC 2.7.11.1) (SRPK)| Length = 742 Score = 52.0 bits (123), Expect = 6e-07 Identities = 43/146 (29%), Positives = 69/146 (47%), Gaps = 14/146 (9%) Frame = +2 Query: 14 GEPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNR---ELQLMR-- 178 GEP + Y+ R +G G F V+ AK + VA+K V D+ Y E++L++ Sbjct: 150 GEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDEIKLLQRV 209 Query: 179 ---------SMDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMP 331 SM +++ L F+ + + + +V E + E L ++K Y + +P Sbjct: 210 NDADNTKEDSMGANHILKLLD-HFNHKGPNGVHVVMVFEVLGENLLALIKKYEHRG--IP 266 Query: 332 LIYVKLYMYQLFRGLAYVHTVPGVCH 409 LIYVK QL GL Y+H G+ H Sbjct: 267 LIYVKQISKQLLLGLDYMHRRCGIIH 292
>CDK8_DROME (Q9VT57) Cell division protein kinase 8 (EC 2.7.11.22) (EC| 2.7.11.23) (DmCdk8) Length = 454 Score = 52.0 bits (123), Expect = 6e-07 Identities = 36/121 (29%), Positives = 64/121 (52%), Gaps = 9/121 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLET--GETVAIKKVLQDRRYKN--RELQLMRSMDHPNVVSLKHCFF 223 VG G++G V++AK ET G+ A+K++ + RE+ L+R + H NV++L F Sbjct: 27 VGRGTYGHVYKAKWKETSDGKEYALKQIDGTGLSMSACREIALLRELKHQNVITLIRVFL 86 Query: 224 STTSRDELFLNLVMEYVPETLYRVLKHYSNANQR-----MPLIYVKLYMYQLFRGLAYVH 388 S R + L+++Y L+ ++K + A +P VK +YQ+ G+ Y+H Sbjct: 87 SHNDRK---VFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLH 143 Query: 389 T 391 + Sbjct: 144 S 144
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 52.0 bits (123), Expect = 6e-07 Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSM---DHPNVVSL 208 +G G++G V++A+ L++G+ VA+K V RE+ L++ + DHPN+V L Sbjct: 15 IGVGAYGTVYKARDLQSGKFVALKNVRVQTNENGLPLSTVREVTLLKRLEHFDHPNIVKL 74 Query: 209 KHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 S + E + LV E+V + L L +PL +K M Q GL ++H Sbjct: 75 MDVCASARTDRETKVTLVFEHVDQDLKTYLSKVPPPG--LPLETIKDLMKQFLSGLEFLH 132
>PLK3_HUMAN (Q9H4B4) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Proliferation-related kinase) Length = 646 Score = 52.0 bits (123), Expect = 6e-07 Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 7/139 (5%) Frame = +2 Query: 17 EPKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-------RELQLM 175 +P+ +Y+ R++G G F ++A ETG A+K + Q R K E++L Sbjct: 55 DPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELH 114 Query: 176 RSMDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYM 355 R + H ++V H F +FL L + L H A + V+ Y+ Sbjct: 115 RDLQHRHIVRFSH-HFEDADNIYIFLELCSR-------KSLAHIWKARHTLLEPEVRYYL 166 Query: 356 YQLFRGLAYVHTVPGVCHR 412 Q+ GL Y+H G+ HR Sbjct: 167 RQILSGLKYLHQ-RGILHR 184
>CCRK_MACMU (Q5EDC3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 243 Score = 52.0 bits (123), Expect = 6e-07 Identities = 42/126 (33%), Positives = 63/126 (50%), Gaps = 7/126 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDR------RYKNRELQLMRSM-DHPNVVSLKH 214 +G G+ GIVF+AK +ETGE VA+KKV R RE++ ++ M D+ VV LK Sbjct: 10 IGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMGDNQYVVQLKA 69 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 F L E++ L V++H A + + VK Y+ L +G+A+ H Sbjct: 70 VFPHGGG-----FVLAFEFMLSDLAEVVRH---AQRPLAQAQVKSYLQMLLKGVAFCH-A 120 Query: 395 PGVCHR 412 + HR Sbjct: 121 NNIVHR 126
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 52.0 bits (123), Expect = 6e-07 Identities = 39/130 (30%), Positives = 62/130 (47%), Gaps = 5/130 (3%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN---RELQLMRSMDHPNVVSL 208 Y R +G+G+FG+ + T E VA+K + + + + RE+ RS+ HPN++ Sbjct: 33 YELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGEKIDDNVQREIINHRSLKHPNIIRF 92 Query: 209 KHCFFSTTSRDELFLNLVMEYVP--ETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 K + T L +VMEY E R+ K N R + + QL G++Y Sbjct: 93 KEVILTPT-----HLAIVMEYASGGELFERICK-----NVRFSEDEARYFFQQLISGVSY 142 Query: 383 VHTVPGVCHR 412 H++ VCHR Sbjct: 143 CHSMQ-VCHR 151
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 52.0 bits (123), Expect = 6e-07 Identities = 42/126 (33%), Positives = 63/126 (50%), Gaps = 7/126 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDR------RYKNRELQLMRSM-DHPNVVSLKH 214 +G G+ GIVF+AK +ETGE VA+KKV R RE++ ++ M D+ VV LK Sbjct: 10 IGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLKA 69 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 F L E++ L V++H A + + VK Y+ L +G+A+ H Sbjct: 70 VFPHGGG-----FVLAFEFMLSDLAEVVRH---AQRPLAQAQVKSYLQMLLKGVAFCH-A 120 Query: 395 PGVCHR 412 + HR Sbjct: 121 NNIVHR 126
>ORB6_SCHPO (O13310) Serine/threonine-protein kinase orb6 (EC 2.7.11.1)| Length = 469 Score = 52.0 bits (123), Expect = 6e-07 Identities = 40/129 (31%), Positives = 67/129 (51%), Gaps = 8/129 (6%) Frame = +2 Query: 50 RVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNREL-------QLMRSMDHPNVVSL 208 +V+G G+FG V + L+TG+ A+K +L+ +K +L L+ D P VVSL Sbjct: 97 KVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLVESDSPWVVSL 156 Query: 209 KHCFFSTTSRDELFLNLVMEYVP-ETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYV 385 + F +D L+L L+ME++P L +L +Y ++ + + YM + +A V Sbjct: 157 YYAF-----QDSLYLYLIMEFLPGGDLMTMLINYDTFSEDV----TRFYMAECVLAIADV 207 Query: 386 HTVPGVCHR 412 H + G HR Sbjct: 208 HRM-GYIHR 215
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 51.6 bits (122), Expect = 8e-07 Identities = 43/135 (31%), Positives = 66/135 (48%), Gaps = 10/135 (7%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAI-----KKVLQDRRYKN---RELQLMRSMDHP 193 Y +++G G+F VF A+ TG++VA+ KK+L + N RE+ +MR + HP Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHP 80 Query: 194 NVVSLKHCFFSTTSRDELFLNLVMEYVP--ETLYRVLKHYSNANQRMPLIYVKLYMYQLF 367 N+V L H +T S+ + ME+V E ++ KH R+ + Y QL Sbjct: 81 NIVKL-HEVMATKSK----IFFAMEFVKGGELFNKISKH-----GRLSEDLSRRYFQQLI 130 Query: 368 RGLAYVHTVPGVCHR 412 + Y H GV HR Sbjct: 131 SAVGYCH-ARGVYHR 144
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 51.6 bits (122), Expect = 8e-07 Identities = 31/117 (26%), Positives = 59/117 (50%), Gaps = 6/117 (5%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G++G+V++ K T VA+KK+ + + RE+ L++ + HPNVV L+ Sbjct: 28 IGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLE-- 85 Query: 218 FFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 E L L+ E++ L R + ++ +PL +K Y +Q+ + + + H Sbjct: 86 ---AVIMQENRLFLIFEFLSFDLKRYMDQLGK-DEYLPLETLKSYTFQILQAMCFCH 138
>TAOK2_XENLA (Q6GPK9) Serine/threonine-protein kinase TAO2 (EC 2.7.11.1)| (Thousand and one amino acid protein 2) Length = 1025 Score = 51.6 bits (122), Expect = 8e-07 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 7/120 (5%) Frame = +2 Query: 50 RVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-------RELQLMRSMDHPNVVSL 208 R +G GSFG V+ A+ + E VAIKK+ + N +E++ ++ + HPN + Sbjct: 32 REIGHGSFGAVYFARDIRNNEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQKLRHPNTIEY 91 Query: 209 KHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 K C+ E LVMEY + +L+ + Q M + + + +GLAY+H Sbjct: 92 KGCYLR-----EHTAWLVMEYCLGSASDLLEVHKKPLQEMEIAAI---THGALQGLAYLH 143
>CDPK3_PLAYO (Q7RAV5) Calcium-dependent protein kinase 3 (EC 2.7.11.1)| Length = 538 Score = 51.6 bits (122), Expect = 8e-07 Identities = 38/130 (29%), Positives = 67/130 (51%), Gaps = 6/130 (4%) Frame = +2 Query: 41 MAERVVGTGSFGIVFQA--KCLETGETVAI--KKVLQDRRYKNRELQLMRSMDHPNVVSL 208 ++E +G G++G V++A K L+ V + KK L++ +E+ +M+++DHPNV+ L Sbjct: 113 LSEEPLGKGTYGCVYKATDKLLKIQRAVKVVSKKKLKNIPRFRQEIDIMKNLDHPNVIKL 172 Query: 209 KHCFFSTTSRDELFLNLVMEYVP--ETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 F DE + L+M+ E +++K S +Y M Q+F L Y Sbjct: 173 LETF-----EDEEQIYLIMDLCTGGELFDKIIKKGSFVE-----MYASFIMKQIFSVLNY 222 Query: 383 VHTVPGVCHR 412 +H + +CHR Sbjct: 223 LH-IRNICHR 231
>SUR1_CAEEL (P39745) Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP| kinase sur-1) Length = 444 Score = 51.6 bits (122), Expect = 8e-07 Identities = 35/130 (26%), Positives = 67/130 (51%), Gaps = 5/130 (3%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKV--LQDRRYKNR---ELQLMRSMDHPNVV 202 Y+ +G G++G+V A T + VAIKK+ + + + R E++++ H N++ Sbjct: 96 YVNLSYIGEGAYGMVASALDTITRDRVAIKKISPFEHQTFCQRTLREIKILNRFKHENII 155 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 +++ S T + +V + LY++LK Q++ +V ++YQ+ RGL Y Sbjct: 156 NIQEIIRSETVDSLKDIYIVQCLMETDLYKLLK-----TQKLSNDHVCYFLYQILRGLKY 210 Query: 383 VHTVPGVCHR 412 +H+ V HR Sbjct: 211 IHSA-NVLHR 219
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 51.6 bits (122), Expect = 8e-07 Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 6/116 (5%) Frame = +2 Query: 59 GTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKHCF 220 G GS+G+VF+ + +G+ VA+KK ++ ++ RE+++++ + HPN+V+L F Sbjct: 11 GEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPNLVNLIEVF 70 Query: 221 FSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 R + ++LV EY TL L+ N + +K ++Q + L + H Sbjct: 71 -----RRKRKMHLVFEYCDHTLLNELERNPNG---VADGVIKSVLWQTLQALNFCH 118
>BUR1_ASPFU (Q4WTN5) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 580 Score = 51.2 bits (121), Expect = 1e-06 Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNVVSLKHC 217 +G G+FG V++A+ + G VA+KK+L RE++L++ + H N++ LK Sbjct: 31 LGEGTFGEVYKARSKKDGSIVALKKILMHNEKDGFPITALREIKLLKMLSHRNILQLKEM 90 Query: 218 FFSTT---SRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + R + + +V Y+ L +L++ + N P +K YM QL GL Y+H Sbjct: 91 AVERSKGDGRKKPSMYMVTPYMEHDLSGLLENPA-VNFTEP--QIKCYMLQLLEGLKYLH 147
>CD2L6_HUMAN (Q9BWU1) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11) Length = 502 Score = 51.2 bits (121), Expect = 1e-06 Identities = 35/120 (29%), Positives = 67/120 (55%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGET--VAIKKVLQDRRYKN--RELQLMRSMDHPNVVSLKHCFF 223 VG G++G V++A+ + + A+K++ + RE+ L+R + HPNV++L+ F Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFL 86 Query: 224 STTSRDELFLNLVMEYVPETLYRVLKHY--SNANQR---MPLIYVKLYMYQLFRGLAYVH 388 S + R + L+ +Y L+ ++K + S AN++ +P VK +YQ+ G+ Y+H Sbjct: 87 SHSDRK---VWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLH 143
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 51.2 bits (121), Expect = 1e-06 Identities = 31/116 (26%), Positives = 61/116 (52%), Gaps = 5/116 (4%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRSMDHPNVVSLKHCF 220 +G G++ V++ + G+ VA+K++ D RE+ LM+ +DH N+V+L Sbjct: 14 LGEGTYATVYKGRNRTNGQLVALKEINLDSEEGTPSTAIREISLMKELDHENIVTLYDVI 73 Query: 221 FSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 + E L LV E++ + L + ++ + N + L VK +++QL +G+ + H Sbjct: 74 HT-----ENKLTLVFEFMDKDLKKYMEAHGNQG-ALDLKIVKSFIFQLLKGIMFCH 123
>MK09_CHICK (P79996) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) Length = 382 Score = 51.2 bits (121), Expect = 1e-06 Identities = 41/134 (30%), Positives = 71/134 (52%), Gaps = 9/134 (6%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN--------RELQLMRSMDHP 193 Y + +G+G+ GIV A G VA+KK+ R ++N REL L++ ++H Sbjct: 26 YQQLKPIGSGAQGIVCAAFDTVLGINVAVKKL--SRPFQNQTHAKRAYRELVLLKCVNHK 83 Query: 194 NVVSLKHCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFR 370 N++SL + F S +E + LVME + L +V+ H ++RM + +YQ+ Sbjct: 84 NIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVI-HMELDHERMSYL-----LYQMLC 137 Query: 371 GLAYVHTVPGVCHR 412 G+ ++H+ G+ HR Sbjct: 138 GIKHLHSA-GIIHR 150
>MK03_RAT (P21708) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 51.2 bits (121), Expect = 1e-06 Identities = 35/130 (26%), Positives = 66/130 (50%), Gaps = 5/130 (3%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKV--LQDRRYKNR---ELQLMRSMDHPNVV 202 Y + +G G++G+V A VAIKK+ + + Y R E+Q++ H NV+ Sbjct: 43 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLGFRHENVI 102 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 ++ + T + +V + + LY++LK +Q++ ++ ++YQ+ RGL Y Sbjct: 103 GIRDILRAPTLEAMRDVYIVQDLMETDLYKLLK-----SQQLSNDHICYFLYQILRGLKY 157 Query: 383 VHTVPGVCHR 412 +H+ V HR Sbjct: 158 IHSA-NVLHR 166
>CD2L6_MOUSE (Q8BWD8) Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)| (CDC2-related protein kinase 6) Length = 501 Score = 51.2 bits (121), Expect = 1e-06 Identities = 35/120 (29%), Positives = 67/120 (55%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGET--VAIKKVLQDRRYKN--RELQLMRSMDHPNVVSLKHCFF 223 VG G++G V++A+ + + A+K++ + RE+ L+R + HPNV++L+ F Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFL 86 Query: 224 STTSRDELFLNLVMEYVPETLYRVLKHY--SNANQR---MPLIYVKLYMYQLFRGLAYVH 388 S + R + L+ +Y L+ ++K + S AN++ +P VK +YQ+ G+ Y+H Sbjct: 87 SHSDRK---VWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLH 143
>BUR1_YARLI (Q6C842) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 706 Score = 51.2 bits (121), Expect = 1e-06 Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%) Frame = +2 Query: 29 TISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDH 190 T SY +G G+FG VF+A+ + T VA+KK+L + RE+++++ + H Sbjct: 35 TESYKPLGKIGEGTFGEVFRAEQITTKRHVALKKILLHSEKEGFPVTALREIRILKLLRH 94 Query: 191 PNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFR 370 NV+ L + + V P + + N + ++ ++K YM QL Sbjct: 95 ENVIPLVDLAVERGDQSKKERGCVYMVTPYMDHDLAGLLGNQSVQLSPAHIKCYMLQLLE 154 Query: 371 GLAYVH 388 G+ Y+H Sbjct: 155 GIGYLH 160
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 51.2 bits (121), Expect = 1e-06 Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 5/123 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKV-LQDRRYKN----RELQLMRSMDHPNV 199 SY +G GS+ V++ K G+ VA+K + LQ+ RE L++ + H N+ Sbjct: 134 SYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANI 193 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 V L + + L LV EYV L + ++ + + VKL+++QL RGL+ Sbjct: 194 VLLHDIIHTKET-----LTLVFEYVHTDLCQYMEQHPGG---LHPDNVKLFLFQLLRGLS 245 Query: 380 YVH 388 Y+H Sbjct: 246 YIH 248
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 50.8 bits (120), Expect = 1e-06 Identities = 34/126 (26%), Positives = 65/126 (51%), Gaps = 6/126 (4%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVLQD------RRYKNRELQLMRSMDHPNVVSLKH 214 +VG GS+G+V + + ++G VAIKK L+ ++ RE++L++ + H N+V+L Sbjct: 9 LVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLE 68 Query: 215 CFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTV 394 + + LV E+V T+ L+ + N V+ Y++Q+ G+ + H+ Sbjct: 69 -----VCKKKKRWYLVFEFVDHTILDDLELFPNGLDDQ---VVQKYLFQIINGIGFCHS- 119 Query: 395 PGVCHR 412 + HR Sbjct: 120 HNIIHR 125
>NLK_MOUSE (O54949) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) Length = 515 Score = 50.8 bits (120), Expect = 1e-06 Identities = 36/137 (26%), Positives = 69/137 (50%), Gaps = 6/137 (4%) Frame = +2 Query: 20 PKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKV------LQDRRYKNRELQLMRS 181 P++ + +R +G G+FG+V+ G+ VA+KK+ L + REL+++ Sbjct: 120 PQQQLDIEPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCF 179 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 H NV+S + +V E + L++++ + Q + +VK+++YQ Sbjct: 180 FKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIV----SPQPLSSDHVKVFLYQ 235 Query: 362 LFRGLAYVHTVPGVCHR 412 + RGL Y+H+ G+ HR Sbjct: 236 ILRGLKYLHSA-GILHR 251
>NLK_HUMAN (Q9UBE8) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) (LAK1 protein) Length = 515 Score = 50.8 bits (120), Expect = 1e-06 Identities = 36/137 (26%), Positives = 69/137 (50%), Gaps = 6/137 (4%) Frame = +2 Query: 20 PKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKV------LQDRRYKNRELQLMRS 181 P++ + +R +G G+FG+V+ G+ VA+KK+ L + REL+++ Sbjct: 120 PQQQLDIEPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCF 179 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQ 361 H NV+S + +V E + L++++ + Q + +VK+++YQ Sbjct: 180 FKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIV----SPQPLSSDHVKVFLYQ 235 Query: 362 LFRGLAYVHTVPGVCHR 412 + RGL Y+H+ G+ HR Sbjct: 236 ILRGLKYLHSA-GILHR 251
>BUR1_GIBZE (Q4I5U9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 473 Score = 50.8 bits (120), Expect = 1e-06 Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 11/122 (9%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRSMDHPNV-----V 202 +G G+FG V +A+ +TG VA+KK++ RE++L++ + H N+ + Sbjct: 43 LGEGTFGEVHRARLRKTGALVALKKIIMHHEKDGFPITALREIKLLKLLSHKNILRLEDM 102 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 +++H T R + + + Y+ L +L N + + +K YM QL GL Y Sbjct: 103 AIEHPTRQTDKRKKPIVYMATPYMDHDLSGLL---DNPSVQFKEPQIKCYMLQLLEGLRY 159 Query: 383 VH 388 +H Sbjct: 160 LH 161
>JAK2_HUMAN (O60674) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 50.8 bits (120), Expect = 1e-06 Identities = 38/121 (31%), Positives = 62/121 (51%), Gaps = 9/121 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCL----ETGETVAIKKVLQDR----RYKNRELQLMRSMDHPNVVSLK 211 +G G+FG V + TGE VA+KK+ R RE+++++S+ H N+V K Sbjct: 855 LGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYK 914 Query: 212 HCFFSTTSRDELFLNLVMEYVPETLYRVLKHY-SNANQRMPLIYVKLYMYQLFRGLAYVH 388 +S R+ L L+MEY+P Y L+ Y +R+ I + Y Q+ +G+ Y+ Sbjct: 915 GVCYSAGRRN---LKLIMEYLP---YGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLG 968 Query: 389 T 391 T Sbjct: 969 T 969
>MK03_MOUSE (Q63844) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 50.8 bits (120), Expect = 1e-06 Identities = 35/130 (26%), Positives = 66/130 (50%), Gaps = 5/130 (3%) Frame = +2 Query: 38 YMAERVVGTGSFGIVFQAKCLETGETVAIKKV--LQDRRYKNR---ELQLMRSMDHPNVV 202 Y + +G G++G+V A VAIKK+ + + Y R E+Q++ H NV+ Sbjct: 43 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVI 102 Query: 203 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAY 382 ++ + T + +V + + LY++LK +Q++ ++ ++YQ+ RGL Y Sbjct: 103 GIRDILRAPTLEAMRDVYIVQDLMETDLYKLLK-----SQQLSNDHICYFLYQILRGLKY 157 Query: 383 VHTVPGVCHR 412 +H+ V HR Sbjct: 158 IHSA-NVLHR 166
>NEK4_MOUSE (Q9Z1J2) Serine/threonine-protein kinase Nek4 (EC 2.7.11.1)| (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) Length = 792 Score = 50.8 bits (120), Expect = 1e-06 Identities = 48/146 (32%), Positives = 67/146 (45%), Gaps = 7/146 (4%) Frame = +2 Query: 20 PKRTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKV------LQDRRYKNRELQLMRS 181 P+ YM RVVG GS+G V K G+ IKK+ ++RR +E QL+ Sbjct: 2 PQAAYCYM--RVVGRGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQ 59 Query: 182 MDHPNVVSLKHCFFSTTSRDELFLNLVMEYVP-ETLYRVLKHYSNANQRMPLIYVKLYMY 358 + HPN+V+ K S D L L +VM + LYR LK Q +P V + Sbjct: 60 LKHPNIVTYKE---SWEGGDGL-LYIVMGFCEGGDLYRKLK--EQKGQLLPESQVVEWFV 113 Query: 359 QLFRGLAYVHTVPGVCHRGCETTKCF 436 Q+ L Y+H + HR +T F Sbjct: 114 QIAMALQYLHE-KHILHRDLKTQNVF 138
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 50.4 bits (119), Expect = 2e-06 Identities = 32/120 (26%), Positives = 60/120 (50%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN---------RELQLMRSMDHPNVVSL 208 +G G F V++A+ T + VAIKK+ R + RE++L++ + HPN++ L Sbjct: 10 LGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGL 69 Query: 209 KHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F ++ ++LV +++ L ++K S + ++K YM +GL Y+H Sbjct: 70 LDAFGHKSN-----ISLVFDFMETDLEVIIKDNSLV---LTPSHIKAYMLMTLQGLEYLH 121
>CDK6_HUMAN (Q00534) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) Length = 326 Score = 50.4 bits (119), Expect = 2e-06 Identities = 44/139 (31%), Positives = 66/139 (47%), Gaps = 11/139 (7%) Frame = +2 Query: 8 KNGEPKRTISYMAERVVGTGSFGIVFQAKCLETG-ETVAIKKVLQDRRYKNRELQLMRSM 184 K+G + Y +G G++G VF+A+ L+ G VA+K+V + L +R + Sbjct: 3 KDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREV 62 Query: 185 ---------DHPNVVSL-KHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPL 334 +HPNVV L C S T R E L LV E+V + L L +P Sbjct: 63 AVLRHLETFEHPNVVRLFDVCTVSRTDR-ETKLTLVFEHVDQDLTTYLDKVPEPG--VPT 119 Query: 335 IYVKLYMYQLFRGLAYVHT 391 +K M+QL RGL ++H+ Sbjct: 120 ETIKDMMFQLLRGLDFLHS 138
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 50.4 bits (119), Expect = 2e-06 Identities = 36/132 (27%), Positives = 68/132 (51%), Gaps = 5/132 (3%) Frame = +2 Query: 53 VVGTGSFGIVFQAKCLETGETVAIKKVL----QDRRYKNRELQLMRSMDHPNVVSLKHCF 220 V+G G FG + ETGE + +K+++ + +R +E+++MR ++HPNV+ F Sbjct: 344 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLK----F 399 Query: 221 FSTTSRDELFLNLVMEYVP-ETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVHTVP 397 +D+ LN + EY+ TL ++K N + + P + + G+AY+H++ Sbjct: 400 IGVLYKDKR-LNFITEYIKGGTLRGIIK---NMDSQYPWSQRVSFAKDIASGMAYLHSM- 454 Query: 398 GVCHRGCETTKC 433 + HR + C Sbjct: 455 NIIHRDLNSHNC 466
>CPK1_CRYNE (Q8NK05) Mitogen-activated protein kinase CPK1 (EC 2.7.11.24)| (Stress-activated protein kinase CPK1) Length = 366 Score = 50.4 bits (119), Expect = 2e-06 Identities = 36/131 (27%), Positives = 65/131 (49%), Gaps = 5/131 (3%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKV-----LQDRRYKNRELQLMRSMDHPNV 199 +Y E +VG G++G+V L +G VAIK++ + RE++L+R H N+ Sbjct: 15 TYKLEEIVGEGAYGLVVAGTHLPSGTQVAIKRITPFDHTMFCQRTLREIKLLRHFHHENI 74 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLA 379 +S+ + + LV E + L+RV++ +Q + + + ++YQ RGL Sbjct: 75 ISILDLIQPESYEVFNEVYLVQELMETDLHRVIR-----SQELSDDHCQYFVYQTLRGLK 129 Query: 380 YVHTVPGVCHR 412 +H+ V HR Sbjct: 130 ALHSA-DVLHR 139
>MK14_XENLA (P47812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2) Length = 361 Score = 50.4 bits (119), Expect = 2e-06 Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 9/128 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQD--------RRYKNRELQLMRSMDHPNVVSLK 211 VG+G++G V + T +A+KK+ + R Y REL+L++ M H NV+ L Sbjct: 31 VGSGAYGSVCSSFDTRTALRIAVKKLSRPFQSIIHAKRTY--RELRLLKHMKHENVIGLL 88 Query: 212 HCFFSTTSRDEL-FLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F S +E + LV + L ++K Q++ +V+ +YQ+ RGL Y+H Sbjct: 89 DVFSPAKSFEEFNDVYLVTHLMGADLNNIVK-----CQKLTDDHVQFLIYQILRGLKYIH 143 Query: 389 TVPGVCHR 412 + G+ HR Sbjct: 144 SA-GIIHR 150
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 50.4 bits (119), Expect = 2e-06 Identities = 32/120 (26%), Positives = 60/120 (50%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN---------RELQLMRSMDHPNVVSL 208 +G G F V++A+ T + VAIKK+ R + RE++L++ + HPN++ L Sbjct: 18 LGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGL 77 Query: 209 KHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F ++ ++LV +++ L ++K S + ++K YM +GL Y+H Sbjct: 78 LDAFGHKSN-----ISLVFDFMETDLEVIIKDNSLV---LTPSHIKAYMLMTLQGLEYLH 129
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 50.4 bits (119), Expect = 2e-06 Identities = 32/120 (26%), Positives = 60/120 (50%), Gaps = 9/120 (7%) Frame = +2 Query: 56 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN---------RELQLMRSMDHPNVVSL 208 +G G F V++A+ T + VAIKK+ R + RE++L++ + HPN++ L Sbjct: 18 LGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGL 77 Query: 209 KHCFFSTTSRDELFLNLVMEYVPETLYRVLKHYSNANQRMPLIYVKLYMYQLFRGLAYVH 388 F ++ ++LV +++ L ++K S + ++K YM +GL Y+H Sbjct: 78 LDAFGHKSN-----ISLVFDFMETDLEVIIKDNSLV---LTPSHIKAYMLMTLQGLEYLH 129
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 50.4 bits (119), Expect = 2e-06 Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 6/124 (4%) Frame = +2 Query: 35 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKV-LQDRRYKN----RELQLMRSMDHPNV 199 SY +G GS+ V++ K G+ VA+K + LQ+ RE L++ + H N+ Sbjct: 134 SYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANI 193 Query: 200 VSLKHCFFSTTSRDELFLNLVMEYVPETLYRVL-KHYSNANQRMPLIYVKLYMYQLFRGL 376 V L + + L LV EYV L + + KH + VKL+++QL RGL Sbjct: 194 VLLHDIIHTKET-----LTLVFEYVHTDLCQYMDKHPGGLHPDN----VKLFLFQLLRGL 244 Query: 377 AYVH 388 +Y+H Sbjct: 245 SYIH 248 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 66,289,207 Number of Sequences: 219361 Number of extensions: 1304243 Number of successful extensions: 4894 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4173 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4335 length of database: 80,573,946 effective HSP length: 101 effective length of database: 58,418,485 effective search space used: 2570413340 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
