>O00754:MA2B1_HUMAN Lysosomal alpha-mannosidase precursor - Homo sapiens (Human)|
          Length = 1011
 Score =  253 bits (646), Expect = 1e-66
 Identities = 154/380 (40%), Positives = 220/380 (57%), Gaps = 5/380 (1%)
 Frame = +1

Query: 94   QKYKYYVGQDGYGNDPQASGAYIFRPKDVVPIKTDGQVPPMILRGPILDEVHQQINSWIY 273
            Q + +Y    G     QASGAYIFRP    P+         +++ P++ EVHQ  ++W  
Sbjct: 639  QTFFWYNASIGDNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCS 698

Query: 274  QITRVYKGKDYVETEFIVGPIPVDDENGKELSTEIITSMATNKTFYTDSSGRDFIKRIRD 453
            Q+ R+Y G+ ++E E+ VGPIPV D  GKE+ +   T + T   FYTDS+GR+ ++R RD
Sbjct: 699  QVVRLYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRD 758

Query: 454  YRSEWKIEVNQPVAGNYYPINLGIYVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRLL 633
            YR  WK+   +PVAGNYYP+N  IY+ DGN +L++L DRS GGSS++DG +ELM+HRRLL
Sbjct: 759  YRPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLL 818

Query: 634  NDDGRGVAEALDEKVCLDDQCEGLVIEGKYYLKID-PQGDGARWRRTFGQELYSP-LLLA 807
             DDGRGV+E L E         G  + G++ + +D  Q   A  R    QE+ +P ++LA
Sbjct: 819  KDDGRGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLA 872

Query: 808  FAEQDGGNWANSHVSSFSAMDPTYSLPENVALLTLEELEDGSVLLRLAHLYEAGEH--KD 981
                   N      + FS +     LP +V LLTL       VLLRL H +  GE   ++
Sbjct: 873  PGGGAAYNLGAPPRTQFSGL--RRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRN 930

Query: 982  LSALASVDLKRVFPDKKVGKIIETSLSANQERAAMEKKRLKWKV-AGPPPKENVARGGPV 1158
            LSA  +++L+ +F    + ++ ET+L ANQ R A    RLKW    GP P +   +   +
Sbjct: 931  LSAPVTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGPTPHQTPYQ---L 985

Query: 1159 DPSKLVVELAPMEIRTFVIS 1218
            DP+ + +E  PMEIRTF+ S
Sbjct: 986  DPANITLE--PMEIRTFLAS 1003

>Q8VHC8:MA2B1_CAVPO Lysosomal alpha-mannosidase precursor - Cavia porcellus (Guinea pig)|
          Length = 1007

 Score =  251 bits (640), Expect = 6e-66
 Identities = 159/412 (38%), Positives = 228/412 (55%), Gaps = 10/412 (2%)
 Frame = +1

Query: 13   YLKLQYDA-AGALSHYSDSKTRVEANFEQKYKYYVGQDGYGNDPQASGAYIFRPKDVVPI 189
            YL+  +    G LS       ++     Q + +Y    G     QASGAYIFRP    P 
Sbjct: 605  YLRASFHPDTGLLSMIEVLDRKLTLPVNQAFFWYNASVGDKRSSQASGAYIFRPSQQWPF 664

Query: 190  KTDGQVPPMILRGPILDEVHQQINSWIYQITRVYKGKDYVETEFIVGPIPVDDENGKELS 369
                     +++  ++ EVHQ   +W  Q+ R+Y G+ ++E E+ VGPIPV D+ GKE+ 
Sbjct: 665  PVSHLARTRLVKTALVQEVHQNFTAWCSQVVRLYSGQRHLELEWTVGPIPVGDKWGKEII 724

Query: 370  TEIITSMATNKTFYTDSSGRDFIKRIRDYRSEWKIEVNQPVAGNYYPINLGIYVEDGNKE 549
            +   T + T   F+TDS+GR+ ++R RDYR  WK+   +PVAGNYYP+N  IY+ DG  +
Sbjct: 725  SRFDTPLETGGVFFTDSNGREVLERRRDYRPSWKLNQTEPVAGNYYPVNSRIYITDGKMQ 784

Query: 550  LSILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAEALDEKVCLDDQCEGLVIEGKYYL 729
            L++L DRS GGSS+ DG +ELM+HRRLL DDGRGV EAL E         G  + G++ L
Sbjct: 785  LTVLTDRSQGGSSMSDGSLELMVHRRLLKDDGRGVGEALQE------PGSGGWVRGRHLL 838

Query: 730  KIDPQGDGARWRRTFGQ-ELYSPLLLAFAEQDGGNWANSHVSS-----FSAMDPTYSLPE 891
             +D   + A   R   + EL +P L+  A   G ++ + H  +     FS +     LP 
Sbjct: 839  LLDTAREAAAEHRLLAEKELLAPQLV-LAPGQGPSYHHDHHEAVPRKQFSGL--RRQLPP 895

Query: 892  NVALLTLEELEDGSVLLRLAHLYEAGE--HKDLSALASVDLKRVFPDKKVGKIIETSLSA 1065
            +V LLTL      ++LLRL H +  GE   ++LS   ++DL+ +F    + ++ ET+L+A
Sbjct: 896  SVRLLTLARWGPDTLLLRLEHQFALGEDSSRNLSLPVTLDLQDLFSTFTITRLQETTLAA 955

Query: 1066 NQERAAMEKKRLKWKV-AGPPPKENVARGGPVDPSKLVVELAPMEIRTFVIS 1218
            NQ RA+    RLKW     P  +  V R   +DPS   + L PMEIRTFV S
Sbjct: 956  NQLRAS--ASRLKWTTEIDPISRPAVPR---LDPSS--ITLQPMEIRTFVAS 1000

>Q60HE9:MA2B1_MACFA Lysosomal alpha-mannosidase precursor - Macaca fascicularis (Crab|
            eating macaque) (Cynomolgus monkey)
          Length = 1012

 Score =  249 bits (635), Expect = 2e-65
 Identities = 154/398 (38%), Positives = 223/398 (56%), Gaps = 5/398 (1%)
 Frame = +1

Query: 40   GALSHYSDSKTRVEANFEQKYKYYVGQDGYGNDPQASGAYIFRPKDVVPIKTDGQVPPMI 219
            G L    +   R+     Q + +Y    G     QASGAYIFRP    P+         +
Sbjct: 622  GLLMEIMNMNQRLLLPVRQTFFWYNASIGDNESDQASGAYIFRPNQQKPLPVSRWAQIRL 681

Query: 220  LRGPILDEVHQQINSWIYQITRVYKGKDYVETEFIVGPIPVDDENGKELSTEIITSMATN 399
            ++ P++ EVHQ  ++W  Q+ R+Y G+ ++E E+ VGPIPV D  GKE+ +   T + T 
Sbjct: 682  VKTPLVQEVHQNFSAWCSQVVRLYPGRRHLELEWSVGPIPVGDTWGKEVISRFDTPLETK 741

Query: 400  KTFYTDSSGRDFIKRIRDYRSEWKIEVNQPVAGNYYPINLGIYVEDGNKELSILVDRSVG 579
              FYTDS+GR+ ++R RDYR  WK+   +PVAGNYYP+N  IY+ DG  +L++L DRS G
Sbjct: 742  GRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRIYITDGKMQLTVLTDRSQG 801

Query: 580  GSSIKDGQIELMLHRRLLNDDGRGVAEALDEKVCLDDQCEGLVIEGKYYLKID-PQGDGA 756
            GSS++DG +ELM+HRRLL DD RGV+E L E         G  + G++ + +D  Q   A
Sbjct: 802  GSSLRDGSLELMVHRRLLKDDERGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAA 855

Query: 757  RWRRTFGQELYSP-LLLAFAEQDGGNWANSHVSSFSAMDPTYSLPENVALLTLEELEDGS 933
              R    QE+ +P ++LA       N      + FS +     LP +V LLTL       
Sbjct: 856  GHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGL--RRELPPSVHLLTLASWGPEM 913

Query: 934  VLLRLAHLYEAGEH--KDLSALASVDLKRVFPDKKVGKIIETSLSANQERAAMEKKRLKW 1107
            +LLRL H +  GE   ++LSA  +++L+ +F    + ++ ET+L ANQ R A    RLKW
Sbjct: 914  LLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKW 971

Query: 1108 KV-AGPPPKENVARGGPVDPSKLVVELAPMEIRTFVIS 1218
                GP P +   +   +DP+ + +E  PMEIRTF+ S
Sbjct: 972  TTNTGPTPHQTPYQ---LDPANITLE--PMEIRTFLAS 1004

>Q29451:MA2B1_BOVIN Lysosomal alpha-mannosidase precursor - Bos taurus (Bovine)|
          Length = 999

 Score =  248 bits (632), Expect = 5e-65
 Identities = 149/407 (36%), Positives = 225/407 (55%), Gaps = 5/407 (1%)
 Frame = +1

Query: 13   YLKLQYDA-AGALSHYSDSKTRVEANFEQKYKYYVGQDGYGNDPQASGAYIFRPKDVVPI 189
            YL+ ++D   G L    + +  +     Q + +Y    G     QASGAYIFRP    P+
Sbjct: 600  YLRARFDPNTGLLMELENLEQNLLLPVRQAFYWYNASTGNNLSSQASGAYIFRPNQNKPL 659

Query: 190  KTDGQVPPMILRGPILDEVHQQINSWIYQITRVYKGKDYVETEFIVGPIPVDDENGKELS 369
                     +++  ++ EVHQ  ++W  Q+ R+Y  + ++E E+ VGPIPV D  GKE+ 
Sbjct: 660  FVSHWAQTHLVKASLVQEVHQNFSAWCSQVVRLYPRQRHLELEWTVGPIPVGDGWGKEVI 719

Query: 370  TEIITSMATNKTFYTDSSGRDFIKRIRDYRSEWKIEVNQPVAGNYYPINLGIYVEDGNKE 549
            +   T++AT   FYTDS+GR+ ++R R+YR  WK+   +PVAGNYYP+N  IY+ DGN +
Sbjct: 720  SRFDTALATRGLFYTDSNGREILERRRNYRPTWKLNQTEPVAGNYYPVNSRIYITDGNMQ 779

Query: 550  LSILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAEALDEKVCLDDQCEGLVIEGKYYL 729
            L++L DRS GGSS++DG +ELM+HRRLL DD RGV E L++      +  GL + G++ +
Sbjct: 780  LTVLTDRSQGGSSLRDGSLELMVHRRLLKDDARGVGEPLNK------EGSGLWVRGRHLV 833

Query: 730  KID-PQGDGARWRRTFGQELYSPLLLAFAEQDGGNWANSHVSSFSAMDPTYSLPENVALL 906
             +D  +   AR R     E+ +P ++  A+  G  +                LP +V LL
Sbjct: 834  LLDKKETAAARHRLQAEMEVLAPQVV-LAQGGGARYRLEKAPRTQFSGLRRELPPSVRLL 892

Query: 907  TLEELEDGSVLLRLAHLYEAGEH--KDLSALASVDLKRVFPDKKVGKIIETSLSANQERA 1080
            TL      ++LLRL H +  GE   ++LS+  ++DL  +F    +  + ET+L+ANQ  A
Sbjct: 893  TLARWGPETLLLRLEHQFAVGEDSGRNLSSPVTLDLTNLFSAFTITNLRETTLAANQLLA 952

Query: 1081 AMEKKRLKWKV-AGPPPKENVARGGPVDPSKLVVELAPMEIRTFVIS 1218
                 RL+W    GP P  + +R     P    + L PMEIRTF+ S
Sbjct: 953  --YASRLQWTTDTGPTPHPSPSR-----PVSATITLQPMEIRTFLAS 992

>O46432:MA2B1_FELCA Lysosomal alpha-mannosidase precursor - Felis silvestris catus (Cat)|
          Length = 1007

 Score =  246 bits (627), Expect = 2e-64
 Identities = 152/383 (39%), Positives = 220/383 (57%), Gaps = 8/383 (2%)
 Frame = +1

Query: 94   QKYKYYVGQDGYGNDPQASGAYIFRPKDVVPIKTDGQVPPMILRGPILDEVHQQINSWIY 273
            Q + +Y    G     Q SGAYIFRP    P+         +++ P++ EVHQ  ++W  
Sbjct: 637  QAFYWYNASVGNNLSTQVSGAYIFRPNQEKPLMVSHWAQTRLVKTPLVQEVHQNFSAWCS 696

Query: 274  QITRVYKGKDYVETEFIVGPIPVDDENGKELSTEIITSMATNKTFYTDSSGRDFIKRIRD 453
            Q+ R+Y+G+ ++E E+ VGPIPV D  GKE+ +   T + T   FYTDS+GR+ ++R RD
Sbjct: 697  QVVRLYRGQRHLELEWTVGPIPVGDGWGKEIISRFDTVLETKGLFYTDSNGREILERRRD 756

Query: 454  YRSEWKIEVNQPVAGNYYPINLGIYVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRLL 633
            YR  WK+   + VAGNYYP+N  IY+ DGN +L++L DRS GGSS++DG +ELM+HRRLL
Sbjct: 757  YRPTWKLNQTETVAGNYYPVNSRIYIRDGNMQLTVLTDRSQGGSSLRDGSMELMVHRRLL 816

Query: 634  NDDGRGVAEALDEKVCLDDQCEGLVIEGKYYLKIDPQGDGARWRRTFGQ-ELYSPLLLAF 810
             DDGRGV EAL     L+D   G  + G++ + +D     A   R   + E+ +P ++  
Sbjct: 817  KDDGRGVGEAL-----LEDGL-GRWVRGRHLVLLDKVRTAATGHRLQAEKEVLTPQVVLA 870

Query: 811  AEQDGGNWANSHV-----SSFSAMDPTYSLPENVALLTLEELEDGSVLLRLAHLYEAGEH 975
                 G  A  H+       FS +     LP +V LLTL   +  ++LLRL H +  GE 
Sbjct: 871  P----GGGAPYHLKVAPRKQFSGL--RRELPPSVHLLTLARWDQKTLLLRLEHQFAVGED 924

Query: 976  K-DLSALASVDLKRVFPDKKVGKIIETSLSANQERAAMEKKRLKWKV-AGPPPKENVARG 1149
              +LS+  ++DL  +F    +  + ET+L ANQ RA+    RLKW    GP P  + +R 
Sbjct: 925  SGNLSSPVTLDLTDLFSAFTITYLQETTLVANQLRAS--ASRLKWTPNTGPTPLPSPSR- 981

Query: 1150 GPVDPSKLVVELAPMEIRTFVIS 1218
              +DP+   + L PMEIRTF+ S
Sbjct: 982  --LDPA--TITLQPMEIRTFLAS 1000

>O09159:MA2B1_MOUSE Lysosomal alpha-mannosidase precursor - Mus musculus (Mouse)|
          Length = 1013

 Score =  232 bits (591), Expect = 3e-60
 Identities = 148/407 (36%), Positives = 221/407 (54%), Gaps = 5/407 (1%)
 Frame = +1

Query: 13   YLKLQYDAA-GALSHYSDSKTRVEANFEQKYKYYVGQDGYGNDPQASGAYIFRPKDVVPI 189
            Y++  +D+  G L    + +  +     Q + +Y    G     QASGAYIFRP    PI
Sbjct: 612  YMRATFDSGTGLLMKIENLEQNLSLPVSQGFFWYNASVGDEESSQASGAYIFRPNVGKPI 671

Query: 190  KTDGQVPPMILRGPILDEVHQQINSWIYQITRVYKGKDYVETEFIVGPIPVDDENGKELS 369
                     +++  ++ EVHQ  ++W  Q+ R+YKG+ ++E E+ VGPIPV D+ GKE+ 
Sbjct: 672  PVSRWAQISLVKTALVQEVHQNFSAWCSQVIRLYKGQRHLELEWTVGPIPVRDDWGKEVI 731

Query: 370  TEIITSMATNKTFYTDSSGRDFIKRIRDYRSEWKIEVNQPVAGNYYPINLGIYVEDGNKE 549
            +   T M T   F+TDS+GR+ +KR  DYR  W +   +PVAGNYYP+N  IY+ DG  +
Sbjct: 732  SRFDTPMKTKGQFFTDSNGREILKRRDDYRPTWTLNQTEPVAGNYYPVNTRIYITDGQMQ 791

Query: 550  LSILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAEALDEKVCLDDQCEGLVIEGKYYL 729
            L++L DRS GGSS++DG +ELM+HRRLL DD RGV+E L E    D       + G++ +
Sbjct: 792  LTVLTDRSQGGSSLQDGSLELMVHRRLLVDDDRGVSEPLLETDTGDK------VRGRHLV 845

Query: 730  KIDPQGD-GARWRRTFGQELYSP-LLLAFAEQDGGNWANSHVSSFSAMDPTYSLPENVAL 903
             +    D  AR R    QE+ +P ++L+       +   +  + FS +     LP  V L
Sbjct: 846  LLSSVSDAAARHRLLAEQEVLAPQVVLSLGGSSPYHSRATPKTQFSGL--RQELPPQVHL 903

Query: 904  LTLEELEDGSVLLRLAHLYEAGEHKD--LSALASVDLKRVFPDKKVGKIIETSLSANQER 1077
            LTL       +LLRL H +   E  D  LS+  +++++ +F    +  + ET+L+ANQ  
Sbjct: 904  LTLARWGPKMLLLRLEHQFALKEDSDRNLSSPVTLNVQNLFQTFTINYLQETTLAANQPL 963

Query: 1078 AAMEKKRLKWKVAGPPPKENVARGGPVDPSKLVVELAPMEIRTFVIS 1218
            +     RLKW     P   +      +DP+   V L PMEIRTF+ S
Sbjct: 964  S--RASRLKWMTNTGP--TSFPEPSKLDPTS--VTLKPMEIRTFLAS 1004

>P34098:MANA_DICDI Lysosomal alpha-mannosidase precursor - Dictyostelium discoideum|
            (Slime mold)
          Length = 1005

 Score =  188 bits (478), Expect = 4e-47
 Identities = 114/375 (30%), Positives = 199/375 (53%), Gaps = 9/375 (2%)
 Frame = +1

Query: 13   YLKLQYDAA-GALSHYSDSKTRVEANFEQKYKYYVGQDGYGNDPQASGAYIFRPKDVVPI 189
            Y+ +Q+ +  G++   ++  + V ++  Q+Y +Y    G  +  Q SGAYIFRP +    
Sbjct: 606  YINVQFSSQDGSILSITNKTSGVTSSITQEYIWYNPSVGNDDSAQCSGAYIFRPVEDFAY 665

Query: 190  KTDGQVPPM-ILRGPILDEVHQQINSWIYQITRVYKGKDYVETEFIVGPIPVDDENGKEL 366
              +   P + I+RG I   + +  ++ + Q  R+Y   D++E E I+GPI + D  GKE+
Sbjct: 666  PYNNATPSVSIIRGEISSSIRRFWSNEMVQTFRLYSNADHLEVEEIIGPIDISDGIGKEI 725

Query: 367  STEIITSMATNKTFYTDSSGRDFIKRIRDYRSEWKIEVNQPVAGNYYPINLGIYVEDGNK 546
             +   T++ T++T+Y+DS G +  KRI +YR  W + V QP +GNY P+N   Y++D N+
Sbjct: 726  VSRYTTTLVTDQTWYSDSQGMEMQKRITNYRPSWNLTVVQPTSGNYVPVNAIAYIQDPNQ 785

Query: 547  EL--SILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAEALDEKVCLDDQCEGLVIEGK 720
             L  +I+ DRS G +S++DGQ+++M+HRR L DDGRGV + ++E           ++   
Sbjct: 786  SLQFTIVTDRSRGCASLRDGQLDMMMHRRTLKDDGRGVGQPMNEST--------QIVTTS 837

Query: 721  YYLKIDPQGDGARWRRTFGQELYSPLLLAF--AEQDGGNWANSHVSSFSAMDPTYSLPEN 894
              +  D         R     L  PLL  F   +Q   +W + +   +S +     LP  
Sbjct: 838  KLIFHDISSYAQSHYRPAALSLSHPLLPMFTTTQQSSNDWNSQYQGVYSPLTSASPLPNG 897

Query: 895  VALLTLEEL--EDGSVLLRLAHLYEA-GEHKDLSALASVDLKRVFPDKKVGKIIETSLSA 1065
            + + TL+ L  +D ++LLR+ ++Y+  G+        ++DL  +F    +    E +L+ 
Sbjct: 898  LKIQTLQWLDNQDNTILLRIENIYQIDGQDSQDPQTITLDLSTIFSTITITSATEMNLTG 957

Query: 1066 NQERAAMEKKRLKWK 1110
             Q+ + +   RLKWK
Sbjct: 958  VQKLSNL--SRLKWK 970

>O54782:MA2B2_MOUSE Epididymis-specific alpha-mannosidase precursor - Mus musculus|
            (Mouse)
          Length = 1018

 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 93/333 (27%), Positives = 150/333 (45%), Gaps = 28/333 (8%)
 Frame = +1

Query: 307  VETEFIVGPIPVDDENGKELSTEIITSMATNKTFYTDSSGRDFIKRIRDYRSEWKIEVNQ 486
            +E ++ VGP+ ++ E     S+++     + +  Y+D++G    +R       +K   + 
Sbjct: 710  IEQQYRVGPLDLNREAILRTSSDL----NSQQVLYSDNNGYQMQRR------PYKAFKSN 759

Query: 487  PVAGNYYPINLGIYVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAEAL 666
            P+  NYYP+    ++ED    L +L +R  G SS  +GQ+E+MLHRRL N+    +A  L
Sbjct: 760  PIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQGNGQVEVMLHRRLWNN----LAWDL 815

Query: 667  DEKVCLDDQCEGLVIEGKYYLKIDPQGDGARWRRTFGQEL-YSP--LLLAFAEQD----- 822
               + L+D     ++    +L + P+          G  L + P  LL   A+++     
Sbjct: 816  KYNLTLNDTS---IVHPVLWLMLGPKSTMTALHPRSGVALQHGPVVLLKELADEETPVHG 872

Query: 823  -GGNW-----ANSHVSSFSAMDPTYSLPENVALLTLE-------ELEDGSVLLRLAHLYE 963
                W      N H+   S    TYS      L  L+       +     VLLRL HLYE
Sbjct: 873  PHNPWPVTLPPNLHLQILSVPGWTYSRSHAQHLRNLQRGHPEKPQANLQRVLLRLRHLYE 932

Query: 964  AGEHKDLSALASVDLKRVFPDKKVGKII---ETSLSANQERAAMEKKRLKWKVAGPPPKE 1134
            AGE   LS  A+VDLK V   + +G ++   E SL+   +   ++  R  W       K 
Sbjct: 933  AGEDPVLSRPATVDLKVVL--RGLGSVVAVEERSLTGTWDVQMLQ--RWHWST-----KT 983

Query: 1135 NVARGGPVDPSK----LVVELAPMEIRTFVISF 1221
            +  +G P  P +     ++ + P EIRTF I F
Sbjct: 984  DHLKGHPTSPPRPPGGSIITVYPKEIRTFFIKF 1016

>Q28949:MA2B2_PIG Epididymis-specific alpha-mannosidase precursor - Sus scrofa (Pig)|
          Length = 995

 Score = 88.6 bits (218), Expect = 6e-17
 Identities = 94/331 (28%), Positives = 147/331 (44%), Gaps = 26/331 (7%)
 Frame = +1

Query: 307  VETEFIVGPIPVDDENGKELSTEIITSMATNKTFYTDSSGRDFIKRIRDYRSEWKIEVNQ 486
            +E E+ VGP+    E   E+     TS+ T    Y+D++G    +R       ++ + N 
Sbjct: 685  IEQEYRVGPL----ELNHEVVLRTSTSLNTGLVLYSDNNGYQMQRRT------YRHDRNN 734

Query: 487  PVAGNYYPINLGIYVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAEAL 666
             V+ NYYP+    +++DG   L +L +++ G SS  +GQ+E+MLHRRL N     +   L
Sbjct: 735  SVSLNYYPMAQSAFIQDGGSRLVLLSEQAHGVSSQGNGQVEVMLHRRLWNKLEWTLQYNL 794

Query: 667  DEKVCLDDQCEGLVIEGKYYLKIDPQGDGARWRRTFGQELYSPLLLAFAEQDGGNWANS- 843
               V         V+    +L + P+      R+  G EL    ++ F E  GG   N  
Sbjct: 795  THDVT-------SVVRPVLWLLLGPRTLTTGLRQRSGLELQHRPVVLFREL-GGTVQNGP 846

Query: 844  --------------HVSSFSAMDPTYSLPENVALLTLE-------ELEDGSVLLRLAHLY 960
                          H+   S     YS    V L  L+       + +   VLLRL HLY
Sbjct: 847  GPRKQEPVTLPPSLHLQILSIPGWKYSSNHTVHLKNLQKGHYRRAKADFRRVLLRLHHLY 906

Query: 961  EAGEHKDLSALASVDLKRVFPDKKVGKII---ETSLSANQERAAMEKKRLKWKVAGPPPK 1131
            EAGEH+ LS   +++L+ V   + +G ++   E SL+   +  ++   R  WK       
Sbjct: 907  EAGEHQALSRPVTLNLQSVL--RGLGSVVAVEERSLTGTWDVNSLH--RWSWKTEDGHHH 962

Query: 1132 ENVARGGPVDPSK-LVVELAPMEIRTFVISF 1221
               +R  P+ P +   V + P EIRTF I F
Sbjct: 963  RGSSR-RPLPPLRGPNVTIHPKEIRTFFIHF 992

>Q24451:MAN2_DROME Alpha-mannosidase 2 - Drosophila melanogaster (Fruit fly)|
          Length = 1108

 Score = 84.7 bits (208), Expect = 8e-16
 Identities = 57/180 (31%), Positives = 91/180 (50%), Gaps = 1/180 (0%)
 Frame = +1

Query: 148  SGAYIFRPKDVVPIKTDGQVPPMILRGPILDEVHQQINSWIYQITRVYKGKDYVETEFIV 327
            SGAY+F P         GQ   ++ +G +   V   + S ++Q T +  G   +     +
Sbjct: 787  SGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQ-TIMRGGAPEIRNLVDI 845

Query: 328  GPIPVDDENGKELSTEIITSMATNKTFYTDSSGRDFIKRIRDYRSEWKIEVNQPVAGNYY 507
            G +     +  E+   + T + +   FYTD +G  FIKR R  +         P+  NYY
Sbjct: 846  GSL-----DNTEIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKL--------PLQANYY 892

Query: 508  PINLGIYVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAE-ALDEKVCL 684
            PI  G+++ED N  L++L  + +GGSS+  G++E+M  RRL +DD RG+ +  LD K  L
Sbjct: 893  PIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVL 952

>Q5RDJ3:MA2B2_PONPY Epididymis-specific alpha-mannosidase precursor - Pongo pygmaeus|
            (Orangutan)
          Length = 1009

 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 104/403 (25%), Positives = 164/403 (40%), Gaps = 45/403 (11%)
 Frame = +1

Query: 148  SGAYIFRP-KDVVPIKTDGQVPPMILRGPILDEVHQQI------NSWIYQI----TRVYK 294
            S  Y+F P K  VP      V   I+ G ++ E+ Q         ++ Y I    T V +
Sbjct: 632  SDNYLFTPGKAAVPAWE--AVEMEIVAGQLVTEIRQYFYRNMTARNYTYAIRSRLTHVPQ 689

Query: 295  GKD------YVETEFIVGPIPVDDENGKELSTEIITSMATNKTFYTDSSGRDFIKRIRDY 456
            G D       +E E+  GP+    E  +E      T++ + +  Y+D++G    +R    
Sbjct: 690  GHDGELLCHRIEQEYQAGPL----ELNREAVLRTSTNLNSQQVIYSDNNGYQMQRR---- 741

Query: 457  RSEWKIEVNQPVAGNYYPINLGIYVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRLLN 636
               +   VN  +A NYYP+    ++EDG   L +L +R+ G SS  +GQ+E+MLHRRL N
Sbjct: 742  --PYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWN 799

Query: 637  DDGRGVAEALDEKVCLDDQCEGLVIEGKYYLKIDPQGDGARWRRTFGQELYSPLLLAFAE 816
            +        L   + L+D     ++    +L +         R+     L    ++ F +
Sbjct: 800  N----FDWDLGYNLTLNDTS---IVHPVLWLLLGSWSLTTALRQRSAMALQHRPVVLFGD 852

Query: 817  QDGGN--------------WANSHVSSFSAMDPTYSLPENVALLTLEELEDGS------- 933
              G                  N H+   S     YS         L +   G        
Sbjct: 853  LAGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHAQNLRKGNRGEVQADLHR 912

Query: 934  VLLRLAHLYEAGEHKDLSALASVDLKRVFPDKKVGKII---ETSLSANQERAAMEKKRLK 1104
            VLLRL HLYE GE   LS   +V+L+ V   + +G ++   E SL+   + + +   R  
Sbjct: 913  VLLRLHHLYEVGEDPVLSQPVTVNLEAVL--QALGSVVAVEERSLTGTWDVSMLH--RWS 968

Query: 1105 WKVAGPPPKENVARGGPVDPSK----LVVELAPMEIRTFVISF 1221
            W+           RG    PS+     ++ + P EIRTF I F
Sbjct: 969  WRTG-----SGRRRGDTTSPSRPPGGPIITVHPKEIRTFFIHF 1006

>Q9Y2E5:MA2B2_HUMAN Epididymis-specific alpha-mannosidase precursor - Homo sapiens|
            (Human)
          Length = 1009

 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 106/406 (26%), Positives = 164/406 (40%), Gaps = 48/406 (11%)
 Frame = +1

Query: 148  SGAYIFRP-KDVVPIKTDGQVPPMILRGPILDEVHQQI------NSWIYQI----TRVYK 294
            S  Y+F P K  VP      V   I+ G ++ E+ Q         ++ Y I    T V +
Sbjct: 632  SDNYLFTPGKAAVPAWE--AVEMEIVAGQLVTEIRQYFYRNMTAQNYTYAIRSRLTHVPQ 689

Query: 295  GKD------YVETEFIVGPIPVDDENGKELSTEIITSMATNKTFYTDSSGRDFIKRIRDY 456
            G D       +E E+  GP+    E  +E      T++ + +  Y+D++G    +R    
Sbjct: 690  GHDGELLCHRIEQEYQAGPL----ELNREAVLRTSTNLNSQQVIYSDNNGYQMQRR---- 741

Query: 457  RSEWKIEVNQPVAGNYYPINLGIYVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRL-- 630
               +   VN  +A NYYP+    ++EDG   L +L +R+ G SS  +GQ+E+MLHRRL  
Sbjct: 742  --PYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWN 799

Query: 631  -----------LNDDGR------------GVAEALDEKVCLDDQCEGLVIEGKYYLKIDP 741
                       LND                +  AL ++  L  Q   +V+ G      D 
Sbjct: 800  NFDWDLGYNLTLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFG------DL 853

Query: 742  QGDGARWRRTFGQE---LYSPLLLAFAEQDGGNWANSHVSSFSAMDPTYSLPENVALLTL 912
             G   +      QE   L   L L      G  ++++H      +   +       L   
Sbjct: 854  AGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRR- 912

Query: 913  EELEDGSVLLRLAHLYEAGEHKDLSALASVDLKRVFPDKKVGKII---ETSLSANQERAA 1083
                   VLLRL HLYE GE   LS   +V+L+ V   + +G ++   E SL+   + + 
Sbjct: 913  -------VLLRLYHLYEVGEDPVLSQPVTVNLQAVL--QALGSVVAVEERSLTGTWDLSM 963

Query: 1084 MEKKRLKWKVAGPPPKENVARGGPVDPSKLVVELAPMEIRTFVISF 1221
            +   R  W+  GP             P   ++ + P EIRTF I F
Sbjct: 964  LH--RWSWR-TGPGRHRGDTTSPSRPPGGPIITVHPKEIRTFFIHF 1006

>P27046:MA2A1_MOUSE Alpha-mannosidase 2 - Mus musculus (Mouse)|
          Length = 1150

 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 58/232 (25%), Positives = 109/232 (46%), Gaps = 10/232 (4%)
 Frame = +1

Query: 13   YLKLQYDAAGALSHYSDSKTRVEANFEQKYKYYVGQDGYGNDPQASGAYIFRPKDVVPIK 192
            +L + +D +G +      +   +   + ++ +Y    G  N    SGAY+F P       
Sbjct: 765  FLAIWFDRSGLMEKVRRKEDSRQHELKVQFLWY----GTTNKRDKSGAYLFLP------- 813

Query: 193  TDGQVPPMI-LRGPIL----DEVHQQINSWIYQIT---RVYKGKDYVETEFIVGPIP-VD 345
             DGQ  P + LR P +      ++  +  ++  +T   R+Y  +        V  I  + 
Sbjct: 814  -DGQGQPYVSLRPPFVRVTRGRIYSDVTCFLEHVTHKVRLYNIQGIEGQSMEVSNIVNIR 872

Query: 346  DENGKELSTEIITSMATNKTFYTDSSGRDFIKRIRDYRSEWKIEVNQPVAGNYYPINLGI 525
            + + +E+   I + +     +YTD +G     +I+  R+  K+    P+  N YP+    
Sbjct: 873  NVHNREIVMRISSKINNQNRYYTDLNGY----QIQPRRTMSKL----PLQANVYPMCTMA 924

Query: 526  YVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAEAL-DEKV 678
            Y++D    L++L  +S+G SS+  GQIE+ + RRL+ DD RG+ + + D K+
Sbjct: 925  YIQDAEHRLTLLSAQSLGASSMASGQIEVFMDRRLMQDDNRGLGQGVHDNKI 976

>Q16706:MA2A1_HUMAN Alpha-mannosidase 2 - Homo sapiens (Human)|
          Length = 1144

 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 51/231 (22%), Positives = 106/231 (45%), Gaps = 11/231 (4%)
 Frame = +1

Query: 13   YLKLQYDAAGALSHYSDSKTRVEANFEQKYKYYVGQDGYGNDPQASGAYIFRPKDVVPIK 192
            ++ L++D  G +      +         ++ +Y    G       SGAY+F P       
Sbjct: 764  FVLLRFDQTGLMKQMMTKEDGKHHEVNVQFSWY----GTTIKRDKSGAYLFLP------- 812

Query: 193  TDGQVPPMILRGPIL-----DEVHQQINSWIYQIT---RVY--KGKDYVETEFIVGPIPV 342
             DG   P +   P         ++ ++  +   +T   R+Y  +G +    E +   + +
Sbjct: 813  -DGNAKPYVYTTPPFVRVTHGRIYSEVTCFFDHVTHRVRLYHIQGIEGQSVE-VSNIVDI 870

Query: 343  DDENGKELSTEIITSMATNKTFYTDSSGRDFIKRIRDYRSEWKIEVNQ-PVAGNYYPINL 519
                 +E++ +I + + +   FYTD +G         Y+ + ++ +++ P+  N YP+  
Sbjct: 871  RKVYNREIAMKISSDIKSQNRFYTDLNG---------YQIQPRMTLSKLPLQANVYPMTT 921

Query: 520  GIYVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAEALDE 672
              Y++D    L++L  +S+G SS+  GQIE+++ RRL+ DD RG+ + + +
Sbjct: 922  MAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQD 972

>P49641:MA2A2_HUMAN Alpha-mannosidase IIx - Homo sapiens (Human)|
          Length = 1139

 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 25/62 (40%), Positives = 44/62 (70%)
 Frame = +1

Query: 487  PVAGNYYPINLGIYVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAEAL 666
            P+  N+YP+ +  Y++D  K L++   +++G SS+KDGQ+E++L RRL+ DD RG+ + L
Sbjct: 906  PLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGL 965

Query: 667  DE 672
             +
Sbjct: 966  KD 967

>P15917:LEF_BACAN Lethal factor precursor - Bacillus anthracis|
          Length = 809

 Score = 33.9 bits (76), Expect = 1.6
 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
 Frame = +1

Query: 928  GSVLLRLAHLYEAGEHKDLSALASVDLKRVFPDKKVGKII--------ETSLSAN----- 1068
            GS L    +LYE     +L+A    DL     + K+ + I        + S+S+N     
Sbjct: 461  GSTLYNKIYLYENMNINNLTATLGADLVDSTDNTKINRGIFNEFKKNFKYSISSNYMIVD 520

Query: 1069 -QERAAMEKKRLKWKVAGPPPKENVARGGPVDPSKLVVE 1182
              ER A++ +RLKW++   P      R G ++  KL+++
Sbjct: 521  INERPALDNERLKWRIQLSPD----TRAGYLENGKLILQ 555

>Q91830:RAG2_XENLA V(D)J recombination-activating protein 2 - Xenopus laevis (African|
           clawed frog)
          Length = 520

 Score = 33.1 bits (74), Expect = 2.8
 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
 Frame = +1

Query: 667 DEKVCLDDQCEGLVIEGKYYLKIDPQGDGAR--WRRTFGQELYSPLLLAFAEQDGGNWAN 840
           DE    +D  +   + G Y++K  P  D  R  W   +  EL  P ++ F  +DGG+W +
Sbjct: 391 DEDTYNEDDEDDESVTG-YWIKCCPDCDMDRNTWEPFYSTELNKPSMI-FCSKDGGHWVH 448

Query: 841 SHVSSFSAMDPTYSLPENVALLTLEELE 924
           S     S     Y    N+     E +E
Sbjct: 449 SQCMDLSETMLKYLSQNNIKYFCNEHVE 476

>Q9KQN9:MINC_VIBCH Probable septum site-determining protein minC - Vibrio cholerae|
          Length = 220

 Score = 33.1 bits (74), Expect = 2.8
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
 Frame = +1

Query: 508 PINLG--IYVEDGNKELSILVDRSVGGSSIKDGQIELMLHRRLLNDDGRGVAEALDEK-- 675
           P+  G  IY +DG  +L IL   S G   I DG I +    R     GR +A A  ++  
Sbjct: 119 PVRSGQQIYAKDG--DLVILSHVSAGAEVIADGSIHIYGTLR-----GRAIAGASGQREA 171

Query: 676 --VCLDDQCEGLVIEGKYYL 729
             +C D Q E + I G+Y+L
Sbjct: 172 RIICHDLQAELISIAGRYWL 191

>Q5VZT2:CJ113_HUMAN Putative uncharacterized protein C10orf113 - Homo sapiens (Human)|
          Length = 145

 Score = 32.7 bits (73), Expect = 3.6
 Identities = 15/30 (50%), Positives = 16/30 (53%)
 Frame = +1

Query: 754 ARWRRTFGQELYSPLLLAFAEQDGGNWANS 843
           ARW R     LY P + A  E D GNWA S
Sbjct: 78  ARWLRRVSFSLYKPPIQAAPEPDPGNWAKS 107

>Q3Z9C5:SYV_DEHE1 Valyl-tRNA synthetase - Dehalococcoides ethenogenes (strain 195)|
          Length = 880

 Score = 32.0 bits (71), Expect = 6.1
 Identities = 20/84 (23%), Positives = 35/84 (41%)
 Frame = +1

Query: 256 INSWIYQITRVYKGKDYVETEFIVGPIPVDDENGKELSTEIITSMATNKTFYTDSSGRDF 435
           I   ++   R Y  K   ET+ IV P P  DE   +   E I                + 
Sbjct: 690 ITEELWSYLRPYLPKSLGETDIIVAPFPQADETCFDEQAESIMGSLV-----------EV 738

Query: 436 IKRIRDYRSEWKIEVNQPVAGNYY 507
           ++ +R+ R+E  +E+++ +  N Y
Sbjct: 739 VRSLRNLRAEHNVEISRYIQANIY 762

>Q0VKX2:ATPA_ALCBS ATP synthase subunit alpha - Alcanivorax borkumensis (strain SK2 /|
           ATCC 700651 / DSM 11573)
          Length = 514

 Score = 31.6 bits (70), Expect = 8.0
 Identities = 15/42 (35%), Positives = 26/42 (61%)
 Frame = +1

Query: 466 WKIEVNQPVAGNYYPINLGIYVEDGNKELSILVDRSVGGSSI 591
           W+ EVN+PV   Y  I+  + +  G +EL I+ DR +G +++
Sbjct: 139 WRREVNEPVQTGYKSIDAMVPIGRGQREL-IIGDRQIGKTAV 179


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 245,531,353
Number of extensions: 5555184
Number of successful extensions: 14642
Number of sequences better than 10.0: 21
Number of HSP's gapped: 14615
Number of HSP's successfully gapped: 23
Length of query: 453
Length of database: 100,686,439
Length adjustment: 117
Effective length of query: 336
Effective length of database: 68,593,924
Effective search space: 23047558464
Effective search space used: 23047558464
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)